LOCUS 001_Delta_SP_beta_auf_Barbe 4081204 bp DNA circular CON 12-JAN-2021 DEFINITION Bacillus subtilis subsp. subtilis str. 168 complete genome. ACCESSION NC_000964 DBLINK BioProject: PRJNA76 BioSample: SAMEA3138188 KEYWORDS RefSeq; complete genome. SOURCE Bacillus subtilis subsp. subtilis str. 168 ORGANISM Bacillus subtilis subsp. subtilis str. 168 Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus. REFERENCE 1 AUTHORS Borriss,R., Danchin,A., Harwood,C.R., Medigue,C., Rocha,E.P.C., Sekowska,A. and Vallenet,D. TITLE Bacillus subtilis, the model Gram-positive bacterium: 20 years of annotation refinement JOURNAL Microb Biotechnol 11 (1), 3-17 (2018) PUBMED 29280348 REFERENCE 2 (bases 1 to 4215606) AUTHORS Belda,E., Sekowska,A., Le, Fevre,F., Morgat,A., Mornico,D., Ouzounis,C., Vallenet,D., Medigue,C. and Danchin,A. TITLE An updated metabolic view of the Bacillus subtilis 168 genome JOURNAL Microbiology (Reading, Engl.) 159 (Pt 4), 757-770 (2013) PUBMED 23429746 REFERENCE 3 (bases 1 to 4215606) AUTHORS Barbe,V., Cruveiller,S., Kunst,F., Lenoble,P., Meurice,G., Sekowska,A., Vallenet,D., Wang,T., Moszer,I., Medigue,C. and Danchin,A. TITLE From a consortium sequence to a unified sequence: the Bacillus subtilis 168 reference genome a decade later JOURNAL Microbiology (Reading, Engl.) 155 (Pt 6), 1758-1775 (2009) PUBMED 19383706 REFERENCE 4 (bases 1 to 4215606) AUTHORS Kunst,F., Ogasawara,N., Moszer,I., Albertini,A.M., Alloni,G., Azevedo,V., Bertero,M.G., Bessieres,P., Bolotin,A., Borchert,S., Borriss,R., Boursier,L., Brans,A., Braun,M., Brignell,S.C., Bron,S., Brouillet,S., Bruschi,C.V., Caldwell,B., Capuano,V., Carter,N.M., Choi,S.K., Cordani,J.J., Connerton,I.F., Cummings,N.J., Daniel,R.A., Denziot,F., Devine,K.M., Dusterhoft,A., Ehrlich,S.D., Emmerson,P.T., Entian,K.D., Errington,J., Fabret,C., Ferrari,E., Foulger,D., Fritz,C., Fujita,M., Fujita,Y., Fuma,S., Galizzi,A., Galleron,N., Ghim,S.Y., Glaser,P., Goffeau,A., Golightly,E.J., Grandi,G., Guiseppi,G., Guy,B.J., Haga,K., Haiech,J., Harwood,C.R., Henaut,A., Hilbert,H., Holsappel,S., Hosono,S., Hullo,M.F., Itaya,M., Jones,L., Joris,B., Karamata,D., Kasahara,Y., Klaerr-Blanchard,M., Klein,C., Kobayashi,Y., Koetter,P., Koningstein,G., Krogh,S., Kumano,M., Kurita,K., Lapidus,A., Lardinois,S., Lauber,J., Lazarevic,V., Lee,S.M., Levine,A., Liu,H., Masuda,S., Mauel,C., Medigue,C., Medina,N., Mellado,R.P., Mizuno,M., Moestl,D., Nakai,S., Noback,M., Noone,D., O'Reilly,M., Ogawa,K., Ogiwara,A., Oudega,B., Park,S.H., Parro,V., Pohl,T.M., Portelle,D., Porwollik,S., Prescott,A.M., Presecan,E., Pujic,P., Purnelle,B., Rapoport,G., Rey,M., Reynolds,S., Rieger,M., Rivolta,C., Rocha,E., Roche,B., Rose,M., Sadaie,Y., Sato,T., Scanlan,E., Schleich,S., Schroeter,R., Scoffone,F., Sekiguchi,J., Sekowska,A., Seror,S.J., Serror,P., Shin,B.S., Soldo,B., Sorokin,A., Tacconi,E., Takagi,T., Takahashi,H., Takemaru,K., Takeuchi,M., Tamakoshi,A., Tanaka,T., Terpstra,P., Togoni,A., Tosato,V., Uchiyama,S., Vandebol,M., Vannier,F., Vassarotti,A., Viari,A., Wambutt,R., Wedler,H., Weitzenegger,T., Winters,P., Wipat,A., Yamamoto,H., Yamane,K., Yasumoto,K., Yata,K., Yoshida,K., Yoshikawa,H.F., Zumstein,E., Yoshikawa,H. and Danchin,A. TITLE The complete genome sequence of the gram-positive bacterium Bacillus subtilis JOURNAL Nature 390 (6657), 249-256 (1997) PUBMED 9384377 REFERENCE 5 (bases 1 to 4215606) CONSRTM NCBI Genome Project TITLE Direct Submission JOURNAL Submitted (17-SEP-2018) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA REFERENCE 6 (bases 1 to 4215606) AUTHORS Genoscope and -,C.E.A. CONSRTM AMAbiotics and Genoscope TITLE Direct Submission JOURNAL Submitted (24-JAN-2013) A. Danchin, AMAbiotics, Bldg G1, 2, rue Gaston Cremieux, 91000 EVRY antoine.danchin@normalesup.org Bldg G1 Genoscope / CEA (Commissariat a l'energie atomique et aux energies alternatives): BP 191 91006 EVRY cedex - FRANCE (E-mail: seqref@genoscope.cns.fr - Web: www.genoscope.cns.fr) REFERENCE 7 (bases 1 to 4215606) AUTHORS Genoscope and -,C.E.A. CONSRTM Institut Pasteur and Genoscope TITLE Direct Submission JOURNAL Submitted (29-JAN-2009) Genoscope - Centre National de Sequencage : BP 191 91006 EVRY cedex - FRANCE (E-mail : seqref@genoscope.cns.fr - Web : www.genoscope.cns.fr) REFERENCE 8 (bases 1 to 4215606) AUTHORS Kunst,F., Ogasawara,N., Yoshikawa,H. and Danchin,A. TITLE Direct Submission JOURNAL Submitted (18-NOV-1997) I. Moszer, A. Danchin, Genetique des Genomes Bacteriens, Institut Pasteur, 28 rue du Docteur Roux, 75724 Paris Cedex 15, FRANCE. E-mail: moszer@pasteur.fr, antoine.danchin@normalesup.org Phone: +33 (0)1 45 68 84 41, Fax: +33 (0)1 45 68 89 48 COMMENT ##gff-version-START## gff-version :: 3 ##gff-version-END## FEATURES Location/Qualifiers S_feature 1..148 /Source="Nicolas_S_feature" /locus_tag="new_1_148" /HighExp="T0.30H, C30, T1.0H, T1.30H, T-0.40H, T0.0H, T2.0H, S2, T-1.10H, T2.30H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="NA" /TUshortPSig="NA" /TUlongSig="NA" /TUlongPSig="NA" /label="S1" S_feature complement(24..297) /Source="Nicolas_S_feature" /locus_tag="new_24_297_c" /HighExp="S8, C30, Etha, S3, S7, S4, Cold, BT, S5, LoTm" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.178448" /TUshortSig="SigK, SigEF" /TUshortPSig="0.621, 0.992" /TUlongSig="NA" /TUlongPSig="NA" /label="S2" promotor_-35 120..124 /Source="Nicolas_upshift_promotors" /id="U1" /multdbtbs="SigA" /comp="M16" /sig="SigA" /pcomp="0.843156843156843" /psig=1 /xcortree=2521 /SigmaFactorBS="tgtccgctttgtggataagattgtgacaacCATTGcaagctc tcgtttatTTTGGTATTATATTTGTGTTttaactcttgattactaatcctacctttcc t" /listShort="S3, dnaA, S5, dnaN, yaaA, recF" /listLong="yaaB, gyrB, S6, gyrA" /label="promotor_-35" promotor_-10 140..159 /Source="Nicolas_upshift_promotors" /id="U1" /multdbtbs="SigA" /comp="M16" /sig="SigA" /pcomp="0.843156843156843" /psig=1 /xcortree=2521 /SigmaFactorBS="tgtccgctttgtggataagattgtgacaacCATTGcaagctc tcgtttatTTTGGTATTATATTTGTGTTttaactcttgattactaatcctacctttcc t" /listShort="S3, dnaA, S5, dnaN, yaaA, recF" /listLong="yaaB, gyrB, S6, gyrA" /label="promotor_-10" S_feature 150..409 /Source="Nicolas_S_feature" /locus_tag="new_150_409" /HighExp="Heat, G180, LPhT, G150, dia15, Oxctl, S1, G135, LBGstat, HPh" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S3" upshifts 150 /Source="Nicolas_upshifts" /id="U1" /multdbtbs="SigA" /comp="M16" /sig="SigA" /pcomp="0.843156843156843" /psig=1 /xcortree=2521 /SigmaFactorBS="tgtccgctttgtggataagattgtgacaacCATTGcaagctc tcgtttatTTTGGTATTATATTTGTGTTttaactcttgattactaatcctacctttcc t" /listShort="S3, dnaA, S5, dnaN, yaaA, recF" /listLong="yaaB, gyrB, S6, gyrA" promotor_-10 complement(285..304) /Source="Nicolas_upshift_promotors" /id="U2" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.621378621378621" /psig="0.621378621378621" /xcortree=272 /SigmaFactorBS="aacacaaaaaaagagcaaatggcgcttaccaTTCGTACACat taaatgttgaaAACATATAATATAGTAGATAaatagcttttcgacaaatttcacaact t" /listShort="S2" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(297) /Source="Nicolas_upshifts" /id="U2" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.621378621378621" /psig="0.621378621378621" /xcortree=272 /SigmaFactorBS="aacacaaaaaaagagcaaatggcgcttaccaTTCGTACACat taaatgttgaaAACATATAATATAGTAGATAaatagcttttcgacaaatttcacaact t" /listShort="S2" /GFF_Attribute="listLong" S_feature complement(299..1067) /Source="Nicolas_S_feature" /locus_tag="new_299_1067_c" /HighExp="S4, LoTm, S3, C30, S5, S7, S6, T5.0H, S8, M9-stat" /AntisenseName="dnaA" /AntisenseCor="-0.57810076860528403" /AntisenseRegPval="-24.7" /CDS_PredictionProba="NA" /TUshortSig="SigEF" /TUshortPSig="0.992" /TUlongSig="NA" /TUlongPSig="NA" /label="S4" promotor_-35 complement(318..326) /Source="Nicolas_upshift_promotors" /id="U2" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.621378621378621" /psig="0.621378621378621" /xcortree=272 /SigmaFactorBS="aacacaaaaaaagagcaaatggcgcttaccaTTCGTACACat taaatgttgaaAACATATAATATAGTAGATAaatagcttttcgacaaatttcacaact t" /listShort="S2" /GFF_Attribute="listLong" /label="promotor_-35" CDS 410..1750 /gene="dnaA" /locus_tag="BSU_00010" /old_locus_tag="BSU00010" /function="16.9: Replicate" /experiment="publication(s) with functional evidences, PMID:2167836, 2846289, 12682299, 16120674, 1779750, 28166228" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 2167836, 2846289, 12682299, 16120674, 1779750, 28166228; Product type f : factor" /codon_start=1 /transl_table=11 /product="chromosomal replication initiator informational ATPase" /protein_id="NP_387882.1" /db_xref="EnsemblGenomes-Gn:BSU00010" /db_xref="EnsemblGenomes-Tr:CAB11777" /db_xref="GOA:P05648" /db_xref="InterPro:IPR001957" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR010921" /db_xref="InterPro:IPR013159" /db_xref="InterPro:IPR013317" /db_xref="InterPro:IPR018312" /db_xref="InterPro:IPR020591" /db_xref="InterPro:IPR024633" /db_xref="InterPro:IPR027417" /db_xref="PDB:4TPS" /db_xref="SubtiList:BG10065" /db_xref="UniProtKB/Swiss-Prot:P05648" /translation="MENILDLWNQALAQIEKKLSKPSFETWMKSTKAHSLQGDTLTIT APNEFARDWLESRYLHLIADTIYELTGEELSIKFVIPQNQDVEDFMPKPQVKKAVKED TSDFPQNMLNPKYTFDTFVIGSGNRFAHAASLAVAEAPAKAYNPLFIYGGVGLGKTHL MHAIGHYVIDHNPSAKVVYLSSEKFTNEFINSIRDNKAVDFRNRYRNVDVLLIDDIQF LAGKEQTQEEFFHTFNTLHEESKQIVISSDRPPKEIPTLEDRLRSRFEWGLITDITPP DLETRIAILRKKAKAEGLDIPNEVMLYIANQIDSNIRELEGALIRVVAYSSLINKDIN ADLAAEALKDIIPSSKPKVITIKEIQRVVGQQFNIKLEDFKAKKRTKSVAFPRQIAMY LSREMTDSSLPKIGEEFGGRDHTTVIHAHEKISKLLADDEQLQQHVKEIKEQLK*" gene 410..1750 /gene="dnaA" /locus_tag="BSU_00010" /old_locus_tag="BSU00010" promotor_-10 complement(1040..1058) /Source="Nicolas_upshift_promotors" /id="U3" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.992007992007992" /psig="0.992007992007992" /xcortree=1004 /SigmaFactorBS="ttcttcgtgtaatgtgttaaatgtatggaaaaattcttcctg ggtttGTTCTTtccccgctaaaaattGAATATCATCTATCAAAAGcacatcaacattt c" /listShort="S4, S2" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1066) /Source="Nicolas_upshifts" /id="U3" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.992007992007992" /psig="0.992007992007992" /xcortree=1004 /SigmaFactorBS="ttcttcgtgtaatgtgttaaatgtatggaaaaattcttcctg ggtttGTTCTTtccccgctaaaaattGAATATCATCTATCAAAAGcacatcaacattt c" /listShort="S4, S2" /GFF_Attribute="listLong" promotor_-35 complement(1074..1079) /Source="Nicolas_upshift_promotors" /id="U3" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.992007992007992" /psig="0.992007992007992" /xcortree=1004 /SigmaFactorBS="ttcttcgtgtaatgtgttaaatgtatggaaaaattcttcctg ggtttGTTCTTtccccgctaaaaattGAATATCATCTATCAAAAGcacatcaacattt c" /listShort="S4, S2" /GFF_Attribute="listLong" /label="promotor_-35" S_feature 1751..1938 /Source="Nicolas_S_feature" /locus_tag="new_1751_1938" /HighExp="G150, Heat, G180, G135, Paraq, Oxctl, dia0, LBGstat, S1, Lbexp" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S5" CDS 1939..3075 /gene="dnaN" /locus_tag="BSU_00020" /old_locus_tag="BSU00020" /EC_number="2.7.7.7" /function="16.9: Replicate" /experiment="publication(s) with functional evidences, PMID:2846289, 11395445, 12682299, 20453097, 23228104, 28878042" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 2846289, 11395445, 12682299, 20453097, 23228104, 28878042; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="DNA polymerase III (beta subunit)" /protein_id="NP_387883.1" /db_xref="EnsemblGenomes-Gn:BSU00020" /db_xref="EnsemblGenomes-Tr:CAB11778" /db_xref="GOA:P05649" /db_xref="InterPro:IPR001001" /db_xref="InterPro:IPR022634" /db_xref="InterPro:IPR022635" /db_xref="InterPro:IPR022637" /db_xref="PDB:4TR6" /db_xref="SubtiList:BG10066" /db_xref="UniProtKB/Swiss-Prot:P05649" /translation="MKFTIQKDRLVESVQDVLKAVSSRTTIPILTGIKIVASDDGVSF TGSDSDISIESFIPKEEGDKEIVTIEQPGSIVLQARFFSEIVKKLPMATVEIEVQNQY LTIIRSGKAEFNLNGLDADEYPHLPQIEEHHAIQIPTDLLKNLIRQTVFAVSTSETRP ILTGVNWKVEQSELLCTATDSHRLALRKAKLDIPEDRSYNVVIPGKSLTELSKILDDN QELVDIVITETQVLFKAKNVLFFSRLLDGNYPDTTSLIPQDSKTEIIVNTKEFLQAID RASLLAREGRNNVVKLSAKPAESIEISSNSPEIGKVVEAIVADQIEGEELNISFSPKY MLDALKVLEGAEIRVSFTGAMRPFLIRTPNDETIVQLILPVRTY*" gene 1939..3075 /gene="dnaN" /locus_tag="BSU_00020" /old_locus_tag="BSU00020" downshifts 3059 /Source="Nicolas_upshifts" /id="D1" /incds=0 /nref=29 /ntot=161 /MaxReadThrough="5.22584" /MaxDrop="4.17087" /score="21.887269" /energy="-14.2" /TU="U1" /idTUdmin="U1" /TUdmin="-572" /isTUend="FALSE" promotor_-35 3140..3144 /Source="Nicolas_upshift_promotors" /id="U4" /multdbtbs="SigA" /comp="M16" /sig="SigA" /pcomp="0.826173826173826" /psig="0.999000999001" /xcortree=2587 /SigmaFactorBS="ttctattcggtatctgctccgacaagttttcCCTTTccctaa ttcgttttttTTTAGTACAATTAGATATTAgtgatatttgaaagaggtcgatataatg g" /listShort="yaaA, recF, yaaB, gyrB, S6, gyrA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3161..3180 /Source="Nicolas_upshift_promotors" /id="U4" /multdbtbs="SigA" /comp="M16" /sig="SigA" /pcomp="0.826173826173826" /psig="0.999000999001" /xcortree=2587 /SigmaFactorBS="ttctattcggtatctgctccgacaagttttcCCTTTccctaa ttcgttttttTTTAGTACAATTAGATATTAgtgatatttgaaagaggtcgatataatg g" /listShort="yaaA, recF, yaaB, gyrB, S6, gyrA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3169 /Source="Nicolas_upshifts" /id="U4" /multdbtbs="SigA" /comp="M16" /sig="SigA" /pcomp="0.826173826173826" /psig="0.999000999001" /xcortree=2587 /SigmaFactorBS="ttctattcggtatctgctccgacaagttttcCCTTTccctaa ttcgttttttTTTAGTACAATTAGATATTAgtgatatttgaaagaggtcgatataatg g" /listShort="yaaA, recF, yaaB, gyrB, S6, gyrA" /GFF_Attribute="listLong" CDS 3206..3421 /gene="rlbA" /locus_tag="BSU_00030" /old_locus_tag="BSU00030" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:24637032, 24939895" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 24637032, 24939895; Product type f: factor" /codon_start=1 /transl_table=11 /product="RNA binding protein involved in ribosome maturation" /protein_id="NP_387884.1" /db_xref="EnsemblGenomes-Gn:BSU00030" /db_xref="EnsemblGenomes-Tr:CAB11779" /db_xref="GOA:P05650" /db_xref="InterPro:IPR002942" /db_xref="InterPro:IPR014330" /db_xref="InterPro:IPR036986" /db_xref="SubtiList:BG10067" /db_xref="UniProtKB/Swiss-Prot:P05650" /translation="MANPISIDTEMITLGQFLKLADVIQSGGMAKWFLSEHEVLVNDE PDNRRGRKLYVGDVVEIEGFGSFQVVN*" gene 3206..3421 /gene="rlbA" /locus_tag="BSU_00030" /old_locus_tag="BSU00030" CDS 3437..4549 /gene="recF" /locus_tag="BSU_00040" /old_locus_tag="BSU00040" /function="16.6: Maintain" /function="16.9: Replicate" /experiment="publication(s) with functional evidences, PMID:15186413, 16061691, 16385024, 22342069" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15186413, 16061691, 16385024, 22342069; Product type f: factor" /codon_start=1 /transl_table=11 /product="RecA filament-DNA complex stabilisation, ssDNA and dsDNA binding, ATP binding" /protein_id="NP_387885.1" /db_xref="EnsemblGenomes-Gn:BSU00040" /db_xref="EnsemblGenomes-Tr:CAB11780" /db_xref="GOA:P05651" /db_xref="InterPro:IPR001238" /db_xref="InterPro:IPR003395" /db_xref="InterPro:IPR018078" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG10068" /db_xref="UniProtKB/Swiss-Prot:P05651" /translation="MYIQNLELTSYRNYDHAELQFENKVNVIIGENAQGKTNLMEAIY VLSMAKSHRTSNDKELIRWDKDYAKIEGRVMKQNGAIPMQLVISKKGKKGKVNHIEQQ KLSQYVGALNTIMFAPEDLNLVKGSPQVRRRFLDMEIGQVSPVYLHDLSLYQKILSQR NHFLKQLQTRKQTDRTMLDVLTDQLVEVAAKVVVKRLQFTAQLEKWAQPIHAGISRGL EELTLKYHTALDVSDPLDLSKIGDSYQEAFSKLREKEIERGVTLSGPHRDDVLFYVNG RDVQTYGSQGQQRTTALSLKLAEIDLIHEEIGEYPILLLDDVLSELDDYRQSHLLHTI QGRVQTFVTTTSVDGIDHETLRQAGMFRVQNGALVK*" gene 3437..4549 /gene="recF" /locus_tag="BSU_00040" /old_locus_tag="BSU00040" misc_feature 3635..3654 /Source="Nicolas_upshift_promotors" /id="U5" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.992007992007992" /psig=1 /xcortree=2750 /SigmaFactorBS="cggacatcaaatgacaaagaacttatacggtgggacaaagac TATGCTAAAATAGAGGGAAGagtgatgaagcaaaacggggcgatcccgatgcagctcg t" /listShort="yaaB, gyrB, S6, gyrA" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 3653 /Source="Nicolas_upshifts" /id="U5" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.992007992007992" /psig=1 /xcortree=2750 /SigmaFactorBS="cggacatcaaatgacaaagaacttatacggtgggacaaagac TATGCTAAAATAGAGGGAAGagtgatgaagcaaaacggggcgatcccgatgcagctcg t" /listShort="yaaB, gyrB, S6, gyrA" /GFF_Attribute="listLong" CDS 4567..4812 /gene="remB" /locus_tag="BSU_00050" /old_locus_tag="BSU00050" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:19363116" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 19363116; Product type r: regulator" /codon_start=1 /transl_table=11 /product="regulator of extracellular matrix formation" /protein_id="NP_387886.2" /db_xref="EnsemblGenomes-Gn:BSU00050" /db_xref="EnsemblGenomes-Tr:CAB11781" /db_xref="InterPro:IPR007169" /db_xref="SubtiList:BG10069" /db_xref="UniProtKB/Swiss-Prot:P37525" /translation="MYIHLGDDFVVSTRDIVGIFDFKANMSPIVEEFLKKQKHKVVPS VNGTPKSIVVTVQNIYYSPLSSSTLKKRAQFMFEIDS*" gene 4567..4812 /gene="remB" /locus_tag="BSU_00050" /old_locus_tag="BSU00050" CDS 4867..6783 /gene="gyrB" /locus_tag="BSU_00060" /old_locus_tag="BSU00060" /EC_number="5.99.1.3" /function="16.2: Construct biomass (Anabolism)" /function="16.9: Replicate" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:12682299, 12767818, 17320901" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12682299, 12767818, 17320901; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="DNA gyrase (subunit B)" /protein_id="NP_387887.1" /db_xref="EnsemblGenomes-Gn:BSU00060" /db_xref="EnsemblGenomes-Tr:CAB11782" /db_xref="GOA:P05652" /db_xref="InterPro:IPR001241" /db_xref="InterPro:IPR002288" /db_xref="InterPro:IPR003594" /db_xref="InterPro:IPR006171" /db_xref="InterPro:IPR011557" /db_xref="InterPro:IPR013506" /db_xref="InterPro:IPR013759" /db_xref="InterPro:IPR013760" /db_xref="InterPro:IPR014721" /db_xref="InterPro:IPR018522" /db_xref="InterPro:IPR020568" /db_xref="InterPro:IPR034160" /db_xref="InterPro:IPR036890" /db_xref="SubtiList:BG10070" /db_xref="UniProtKB/Swiss-Prot:P05652" /translation="MEQQQNSYDENQIQVLEGLEAVRKRPGMYIGSTNSKGLHHLVWE IVDNSIDEALAGYCTDINIQIEKDNSITVVDNGRGIPVGIHEKMGRPAVEVIMTVLHA GGKFDGSGYKVSGGLHGVGASVVNALSTELDVTVHRDGKIHRQTYKRGVPVTDLEIIG ETDHTGTTTHFVPDPEIFSETTEYDYDLLANRVRELAFLTKGVNITIEDKREGQERKN EYHYEGGIKSYVEYLNRSKEVVHEEPIYIEGEKDGITVEVALQYNDSYTSNIYSFTNN INTYEGGTHEAGFKTGLTRVINDYARKKGLIKENDPNLSGDDVREGLTAIISIKHPDP QFEGQTKTKLGNSEARTITDTLFSTAMETFMLENPDAAKKIVDKGLMAARARMAAKKA RELTRRKSALEISNLPGKLADCSSKDPSISELYIVEGDSAGGSAKQGRDRHFQAILPL RGKILNVEKARLDKILSNNEVRSMITALGTGIGEDFNLEKARYHKVVIMTDADVDGAH IRTLLLTFFYRYMRQIIENGYVYIAQPPLYKVQQGKRVEYAYNDKELEELLKTLPQTP KPGLQRYKGLGEMNATQLWETTMDPSSRTLLQVTLEDAMDADETFEMLMGDKVEPRRN FIEANARYVKNLDI*" gene 4867..6783 /gene="gyrB" /locus_tag="BSU_00060" /old_locus_tag="BSU00060" promotor_-10 complement(6412..6430) /Source="Nicolas_upshift_promotors" /id="U6" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1200 /SigmaFactorBS="cggcggctgcgcaatgtacacgtAGCCATtttcgataatttg gcGCATATATCTGTAAAAGAAcgttaacagcagtgttctgatgtgcgcgccgtcaaca t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(6414) /Source="Nicolas_upshifts" /id="U6" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1200 /SigmaFactorBS="cggcggctgcgcaatgtacacgtAGCCATtttcgataatttg gcGCATATATCTGTAAAAGAAcgttaacagcagtgttctgatgtgcgcgccgtcaaca t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(6446..6451) /Source="Nicolas_upshift_promotors" /id="U6" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1200 /SigmaFactorBS="cggcggctgcgcaatgtacacgtAGCCATtttcgataatttg gcGCATATATCTGTAAAAGAAcgttaacagcagtgttctgatgtgcgcgccgtcaaca t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" S_feature 6784..6993 /Source="Nicolas_S_feature" /locus_tag="new_6784_6993" /HighExp="Cold, H2O2, G180, Oxctl, G135, G150, Sw, dia15, LBGexp, Paraq" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="1, 0.999" /TUlongSig="SigA" /TUlongPSig=1 /label="S6" CDS 6994..9459 /gene="gyrA" /locus_tag="BSU_00070" /old_locus_tag="BSU00070" /EC_number="5.99.1.3" /function="16.3: Control" /function="16.2: Construct biomass (Anabolism)" /function="16.9: Replicate" /experiment="publication(s) with functional evidences, PMID:12682299, 12767818, 17320901, 27557712" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12682299, 12767818, 17320901, 27557712; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="DNA gyrase (subunit A)" /protein_id="NP_387888.1" /db_xref="EnsemblGenomes-Gn:BSU00070" /db_xref="EnsemblGenomes-Tr:CAB11783" /db_xref="GOA:P05653" /db_xref="InterPro:IPR002205" /db_xref="InterPro:IPR005743" /db_xref="InterPro:IPR006691" /db_xref="InterPro:IPR013757" /db_xref="InterPro:IPR013758" /db_xref="InterPro:IPR013760" /db_xref="InterPro:IPR024946" /db_xref="InterPro:IPR035516" /db_xref="PDB:4DDQ" /db_xref="SubtiList:BG10071" /db_xref="UniProtKB/Swiss-Prot:P05653" /translation="MSEQNTPQVREINISQEMRTSFLDYAMSVIVSRALPDVRDGLKP VHRRILYAMNDLGMTSDKPYKKSARIVGEVIGKYHPHGDSAVYESMVRMAQDFNYRYM LVDGHGNFGSVDGDSAAAMRYTEARMSKISMEILRDITKDTIDYQDNYDGSEREPVVM PSRFPNLLVNGAAGIAVGMATNIPPHQLGEIIDGVLAVSENPDITIPELMEVIPGPDF PTAGQILGRSGIRKAYESGRGSITIRAKAEIEQTSSGKERIIVTELPYQVNKAKLIEK IADLVRDKKIEGITDLRDESDRTGMRIVIEIRRDANANVILNNLYKQTALQTSFGINL LALVDGQPKVLTLKQCLEHYLDHQKVVIRRRTAYELRKAEARAHILEGLRVALDHLDA VISLIRNSQTAEIARTGLIEQFSLTEKQAQAILDMRLQRLTGLEREKIEEEYQSLVKL IAELKDILANEYKVLEIIREELTEIKERFNDERRTEIVTSGLETIEDEDLIERENIVV TLTHNGYVKRLPASTYRSQKRGGKGVQGMGTNEDDFVEHLISTSTHDTILFFSNKGKV YRAKGYEIPEYGRTAKGIPIINLLEVEKGEWINAIIPVTEFNAELYLFFTTKHGVSKR TSLSQFANIRNNGLIALSLREDDELMGVRLTDGTKQIIIGTKNGLLIRFPETDVREMG RTAAGVKGITLTDDDVVVGMEILEEESHVLIVTEKGYGKRTPAEEYRTQSRGGKGLKT AKITENNGQLVAVKATKGEEDLMIITASGVLIRMDINDISITGRVTQGVRLIRMAEEE HVATVALVEKNEEDENEEEQEEV*" gene 6994..9459 /gene="gyrA" /locus_tag="BSU_00070" /old_locus_tag="BSU00070" promotor_-35 9373..9376 /Source="Nicolas_upshift_promotors" /id="U7" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.418581418581419" /psig="0.9000999000999" /xcortree=2642 /SigmaFactorBS="tggacatcaatgatatctccatcaccggacgtgtcactcaag gtgtgcgtctcatcagaATGGcagaagaagagcatgtTGCTACAGTAGCTTTAGTtga g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 9374 /Source="Nicolas_upshifts" /id="U7" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.418581418581419" /psig="0.9000999000999" /xcortree=2642 /SigmaFactorBS="tggacatcaatgatatctccatcaccggacgtgtcactcaag gtgtgcgtctcatcagaATGGcagaagaagagcatgtTGCTACAGTAGCTTTAGTtga g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 9393..9410 /Source="Nicolas_upshift_promotors" /id="U7" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.418581418581419" /psig="0.9000999000999" /xcortree=2642 /SigmaFactorBS="tggacatcaatgatatctccatcaccggacgtgtcactcaag gtgtgcgtctcatcagaATGGcagaagaagagcatgtTGCTACAGTAGCTTTAGTtga g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" downshifts 9440 /Source="Nicolas_upshifts" /id="D2" /incds=0 /nref=251 /ntot=261 /MaxReadThrough="3.73971" /MaxDrop="8.1288" /score="33.5021066" /energy="-14.1" /TU="NA" /idTUdmin="U4" /TUdmin=0 /isTUend="TRUE" promotor_-35 9504..9510 /Source="Nicolas_upshift_promotors" /id="U8" /multdbtbs="SigA" /comp="M17" /sig="SigA" /pcomp="0.798201798201798" /psig=1 /xcortree=2622 /SigmaFactorBS="cagctgaaatagctgcgcttttttgtgtcataaccCTTTACA gtcataaaaattaTGGTATAATCATTTCTGTTGtctttttaaagacacaagcatgacc a" /listShort="S7, rrnO-16S" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 9524..9543 /Source="Nicolas_upshift_promotors" /id="U8" /multdbtbs="SigA" /comp="M17" /sig="SigA" /pcomp="0.798201798201798" /psig=1 /xcortree=2622 /SigmaFactorBS="cagctgaaatagctgcgcttttttgtgtcataaccCTTTACA gtcataaaaattaTGGTATAATCATTTCTGTTGtctttttaaagacacaagcatgacc a" /listShort="S7, rrnO-16S" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 9529..9614 /Source="Nicolas_S_feature" /locus_tag="new_9529_9614" /HighExp="LBGstat, H2O2, Paraq, Oxctl, UNK1, LBGexp, LPhT, MG-0.2, MG 25, G180" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S7" upshifts 9529 /Source="Nicolas_upshifts" /id="U8" /multdbtbs="SigA" /comp="M17" /sig="SigA" /pcomp="0.798201798201798" /psig=1 /xcortree=2622 /SigmaFactorBS="cagctgaaatagctgcgcttttttgtgtcataaccCTTTACA gtcataaaaattaTGGTATAATCATTTCTGTTGtctttttaaagacacaagcatgacc a" /listShort="S7, rrnO-16S" /GFF_Attribute="listLong" promotor_-35 9600..9607 /Source="Nicolas_upshift_promotors" /id="U9" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.889110889110889" /psig=1 /xcortree=2634 /SigmaFactorBS="cacaagcatgaccattatgactagtaaaaactttttcaaaaa agTATTGACCtagttaactaaaaaTGTTACTATTAAGTAGTCGCtttgagagaagcac a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 9616 /Source="Nicolas_upshifts" /id="U9" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.889110889110889" /psig=1 /xcortree=2634 /SigmaFactorBS="cacaagcatgaccattatgactagtaaaaactttttcaaaaa agTATTGACCtagttaactaaaaaTGTTACTATTAAGTAGTCGCtttgagagaagcac a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 9622..9641 /Source="Nicolas_upshift_promotors" /id="U9" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.889110889110889" /psig=1 /xcortree=2634 /SigmaFactorBS="cacaagcatgaccattatgactagtaaaaactttttcaaaaa agTATTGACCtagttaactaaaaaTGTTACTATTAAGTAGTCGCtttgagagaagcac a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" rRNA 9810..11364 /gene="rrnO-16S" /locus_tag="BSU_rRNA_1" /product="ribosomal RNA-16S" /note="Evidence 1a: Function from experimental evidences in the studied strain; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene 9810..11364 /gene="rrnO-16S" /locus_tag="BSU_rRNA_1" tRNA 11464..11540 /gene="trnO-Ile" /locus_tag="BSU_tRNA_5" /product="tRNA-Ile" /inference="profile:tRNAscan:1.23" /note="Evidence 2a: Function from experimental evidences in other organisms; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene 11464..11540 /gene="trnO-Ile" /locus_tag="BSU_tRNA_5" tRNA 11552..11627 /gene="trnO-Ala" /locus_tag="BSU_tRNA_6" /product="tRNA-Ala" /inference="profile:tRNAscan:1.23" /note="transfer RNA-Ala(UGC); Evidence 2a: Function from experimental evidences in other organisms; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene 11552..11627 /gene="trnO-Ala" /locus_tag="BSU_tRNA_6" rRNA 11709..14636 /gene="rrnO-23S" /locus_tag="BSU_rRNA_2" /product="ribosomal RNA-23S" /note="Evidence 1a: Function from experimental evidences in the studied strain; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene 11709..14636 /gene="rrnO-23S" /locus_tag="BSU_rRNA_2" rRNA 14692..14810 /gene="rrnO-5S" /locus_tag="BSU_rRNA_3" /product="ribosomal RNA-5S" /note="Evidence 1a: Function from experimental evidences in the studied strain; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene 14692..14810 /gene="rrnO-5S" /locus_tag="BSU_rRNA_3" S_feature 14811..15868 /Source="Nicolas_S_feature" /locus_tag="new_14811_15868" /HighExp="G180, T0.0H, T0.30H, G135, T-0.40H, LBGstat, Cold, Paraq, C30, Oxctl" /AntisenseName="yaaC" /AntisenseCor="-4.5985764709218099E-2" /AntisenseRegPval="-0.3" /CDS_PredictionProba="NA" /TUshortSig="NA" /TUshortPSig="NA" /TUlongSig="NA" /TUlongPSig="NA" /label="S8" CDS complement(14847..15794) /gene="yaaC" /locus_tag="BSU_00080" /old_locus_tag="BSU00080" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 22333191" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_387889.1" /db_xref="EnsemblGenomes-Gn:BSU00080" /db_xref="EnsemblGenomes-Tr:CAB11784" /db_xref="InterPro:IPR026988" /db_xref="SubtiList:BG10072" /db_xref="UniProtKB/Swiss-Prot:P37526" /translation="MTYHEWKDLALFYSVESTQKFLEKVYILNGINDAKKNSFKNSER FIYFLKHAESFYKQAAYSPLEIKPILLFYGMAQLIKACLITRDPHYPSHTSVLAHGVT TRKRKKQNYCFSDDEVKIQRNGLCVHFMKHLFGQSDIVDERYTMKKLLMAIPELSDIF YFQQKERFMTKVEKDKNEIFVPEEVVINYKMSDSRFAEYMSHHYQWSFTKKNEHGLLF EISPQDKEPWTSTSLLFDMEKNQYYIPSQREQFLRLPEMTIHYLILYNVGMIARYETE WWYELLTQHISDDYVLIQQFLLVSEKKFPKYASQFLLHF*" gene complement(14847..15794) /gene="yaaC" /locus_tag="BSU_00080" /old_locus_tag="BSU00080" promotor_-35 15847..15854 /Source="Nicolas_upshift_promotors" /id="U10" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.721278721278721" /psig=1 /xcortree=2668 /SigmaFactorBS="ctttccgttatctaaatatttcaactctttcccgcttCCTTG ACAtgctcttggctagtTGATAATCTACATATAATATtttgccgaaaagagggggatt t" /listShort="guaB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 15869..15888 /Source="Nicolas_upshift_promotors" /id="U10" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.721278721278721" /psig=1 /xcortree=2668 /SigmaFactorBS="ctttccgttatctaaatatttcaactctttcccgcttCCTTG ACAtgctcttggctagtTGATAATCTACATATAATATtttgccgaaaagagggggatt t" /listShort="guaB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 15870 /Source="Nicolas_upshifts" /id="U10" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.721278721278721" /psig=1 /xcortree=2668 /SigmaFactorBS="ctttccgttatctaaatatttcaactctttcccgcttCCTTG ACAtgctcttggctagtTGATAATCTACATATAATATtttgccgaaaagagggggatt t" /listShort="guaB" /GFF_Attribute="listLong" upshifts complement(15875) /Source="Nicolas_upshifts" /id="U11" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.89010989010989" /psig="0.89010989010989" /xcortree=947 /SigmaFactorBS="tgaaaatttactttcccacaTTAGTAAatccccctcttttCG GCAAAATATTatatgtagattatcaactagccaagagcatgtcaaggaagcgggaaag a" /listShort="yaaC" /GFF_Attribute="listLong" promotor_-10 complement(15884..15895) /Source="Nicolas_upshift_promotors" /id="U11" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.89010989010989" /psig="0.89010989010989" /xcortree=947 /SigmaFactorBS="tgaaaatttactttcccacaTTAGTAAatccccctcttttCG GCAAAATATTatatgtagattatcaactagccaagagcatgtcaaggaagcgggaaag a" /listShort="yaaC" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 complement(15909..15915) /Source="Nicolas_upshift_promotors" /id="U11" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.89010989010989" /psig="0.89010989010989" /xcortree=947 /SigmaFactorBS="tgaaaatttactttcccacaTTAGTAAatccccctcttttCG GCAAAATATTatatgtagattatcaactagccaagagcatgtcaaggaagcgggaaag a" /listShort="yaaC" /GFF_Attribute="listLong" /label="promotor_-35" CDS 15915..17381 /gene="guaB" /locus_tag="BSU_00090" /old_locus_tag="BSU00090" /EC_number="1.1.1.205" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:12682299, 1722815, 17611193, 1979163, 3125411, 8917437" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12682299, 1722815, 17611193, 1979163, 3125411, 8917437; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="inosine-monophosphate dehydrogenase" /protein_id="NP_387890.1" /db_xref="EnsemblGenomes-Gn:BSU00090" /db_xref="EnsemblGenomes-Tr:CAB11785" /db_xref="GOA:P21879" /db_xref="InterPro:IPR000644" /db_xref="InterPro:IPR001093" /db_xref="InterPro:IPR005990" /db_xref="InterPro:IPR013785" /db_xref="InterPro:IPR015875" /db_xref="SubtiList:BG10073" /db_xref="UniProtKB/Swiss-Prot:P21879" /translation="MWESKFSKEGLTFDDVLLVPAKSEVLPRDVDLSVELTKTLKLNI PVISAGMDTVTESAMAIAMARQGGLGIIHKNMSIEQQAEQVDKVKRSERGVITNPFFL TPDHQVFDAEHLMGKYRISGVPIVNNEEDQKLVGIITNRDLRFISDYSMKISDVMTKE ELVTASVGTTLDEAEKILQKHKIEKLPLVDDQNKLKGLITIKDIEKVIEFPNSSKDIH GRLIVGAAVGVTGDTMTRVKKLVEANVDVIVIDTAHGHSQGVLNTVTKIRETYPELNI IAGNVATAEATRALIEAGADVVKVGIGPGSICTTRVVAGVGVPQITAIYDCATEARKH GKTIIADGGIKFSGDITKALAAGGHAVMLGSLLAGTSESPGETEIYQGRRFKVYRGMG SVAAMEKGSKDRYFQEENKKFVPEGIEGRTPYKGPVEETVYQLVGGLRSGMGYCGSKD LRALREEAQFIRMTGAGLRESHPHDVQITKESPNYTIS*" gene 15915..17381 /gene="guaB" /locus_tag="BSU_00090" /old_locus_tag="BSU00090" downshifts complement(15919) /Source="Nicolas_upshifts" /id="D3" /incds=0 /nref=33 /ntot=102 /MaxReadThrough="1.81989" /MaxDrop="4.44626" /score="-6.76739893" /energy="-12.2" /TU="NA" /idTUdmin="U12" /TUdmin=0 /isTUend="TRUE" promotor_no_box complement(15945..16045) /Source="Nicolas_upshift_promotors" /id="U12" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.922077922077922" /psig="0.016983016983017" /xcortree=82 /SigmaFactorBS="atatttagctttaacgtttttgtaagttctacagataaatcc acatcacgcggaagtacctcagactttgctggtacaagcagcacatcgtcgaacgtta a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_no_box" upshifts complement(15985) /Source="Nicolas_upshifts" /id="U12" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.922077922077922" /psig="0.016983016983017" /xcortree=82 /SigmaFactorBS="atatttagctttaacgtttttgtaagttctacagataaatcc acatcacgcggaagtacctcagactttgctggtacaagcagcacatcgtcgaacgtta a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" S_feature complement(17238..17833) /Source="Nicolas_S_feature" /locus_tag="new_17238_17833_c" /HighExp="Etha, Gly, C30, Salt, S8, S6, HiTm, S7, Sw, C90" /AntisenseName="dacA" /AntisenseCor="-0.39306815699287101" /AntisenseRegPval="-10.6" /CDS_PredictionProba="NA" /TUshortSig="SigB" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S9" downshifts 17369 /Source="Nicolas_upshifts" /id="D4" /incds=0 /nref=243 /ntot=277 /MaxReadThrough="3.34899" /MaxDrop="7.78161" /score="26.7620012" /energy="-10.6" /TU="NA" /idTUdmin="U10" /TUdmin="-14" /isTUend="TRUE" promotor_-35 17427..17431 /Source="Nicolas_upshift_promotors" /id="U13" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.948051948051948" /psig=1 /xcortree=2602 /SigmaFactorBS="aaattaaaaacatttgacagggtctctgactctgTCTATttt ttttatactgatTATGATAAAATTTATACTGTtgtgcattgaaaatgtccttaacggc t" /listShort="S10, dacA, S11, S12, pdxS, pdxT, NA, serS" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 17447..17466 /Source="Nicolas_upshift_promotors" /id="U13" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.948051948051948" /psig=1 /xcortree=2602 /SigmaFactorBS="aaattaaaaacatttgacagggtctctgactctgTCTATttt ttttatactgatTATGATAAAATTTATACTGTtgtgcattgaaaatgtccttaacggc t" /listShort="S10, dacA, S11, S12, pdxS, pdxT, NA, serS" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 17453..17533 /Source="Nicolas_S_feature" /locus_tag="new_17453_17533" /HighExp="C30, LBGstat, G180, G150, LBGexp, G135, Lbexp, Oxctl, dia0, MG 25" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S10" upshifts 17453 /Source="Nicolas_upshifts" /id="U13" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.948051948051948" /psig=1 /xcortree=2602 /SigmaFactorBS="aaattaaaaacatttgacagggtctctgactctgTCTATttt ttttatactgatTATGATAAAATTTATACTGTtgtgcattgaaaatgtccttaacggc t" /listShort="S10, dacA, S11, S12, pdxS, pdxT, NA, serS" /GFF_Attribute="listLong" CDS 17534..18865 /gene="dacA" /locus_tag="BSU_00100" /old_locus_tag="BSU00100" /EC_number="3.4.16.4" /experiment="publication(s) with functional evidences, PMID:8370539, 9864321, 10383963, 21378199" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8370539, 9864321, 10383963, 21378199; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5)" /protein_id="NP_387891.1" /db_xref="EnsemblGenomes-Gn:BSU00100" /db_xref="EnsemblGenomes-Tr:CAB11786" /db_xref="GOA:P08750" /db_xref="InterPro:IPR001967" /db_xref="InterPro:IPR012338" /db_xref="InterPro:IPR012907" /db_xref="InterPro:IPR015956" /db_xref="InterPro:IPR018044" /db_xref="InterPro:IPR037167" /db_xref="SubtiList:BG10074" /db_xref="UniProtKB/Swiss-Prot:P08750" /translation="MNIKKCKQLLMSLVVLTLAVTCLAPMSKAKAASDPIDINASAAI MIEASSGKILYSKNADKRLPIASMTKMMTEYLLLEAIDQGKVKWDQTYTPDDYVYEIS QDNSLSNVPLRKDGKYTVKELYQATAIYSANAAAIAIAEIVAGSETKFVEKMNAKAKE LGLTDYKFVNATGLENKDLHGHQPEGTSVNEESEVSAKDMAVLADHLITDYPEILETS SIAKTKFREGTDDEMDMPNWNFMLKGLVSEYKKATVDGLKTGSTDSAGSCFTGTAERN GMRVITVVLNAKGNLHTGRFDETKKMFDYAFDNFSMKEIYAEGDQVKGHKTISVDKGK EKEVGIVTNKAFSLPVKNGEEKNYKAKVTLNKDNLTAPVKKGTKVGKLTAEYTGDEKD YGFLNSDLAGVDLVTKENVEKANWFVLTMRSIGGFFAGIWGSIVDTVTGWF*" gene 17534..18865 /gene="dacA" /locus_tag="BSU_00100" /old_locus_tag="BSU00100" promotor_-10 complement(17822..17840) /Source="Nicolas_upshift_promotors" /id="U14" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=212 /SigmaFactorBS="tactgtgtatttcccgtctttccgaagaggaaCGTTTGAtaa gctgttatcttGGGAAATTTCATACACATAgtcatcaggcgtataggtttggtcccat t" /listShort="S9" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(17833) /Source="Nicolas_upshifts" /id="U14" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=212 /SigmaFactorBS="tactgtgtatttcccgtctttccgaagaggaaCGTTTGAtaa gctgttatcttGGGAAATTTCATACACATAgtcatcaggcgtataggtttggtcccat t" /listShort="S9" /GFF_Attribute="listLong" promotor_-35 complement(17855..17861) /Source="Nicolas_upshift_promotors" /id="U14" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=212 /SigmaFactorBS="tactgtgtatttcccgtctttccgaagaggaaCGTTTGAtaa gctgttatcttGGGAAATTTCATACACATAgtcatcaggcgtataggtttggtcccat t" /listShort="S9" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 18747 /Source="Nicolas_upshifts" /id="D5" /incds=1 /nref=1 /ntot=20 /MaxReadThrough="6.76335" /MaxDrop="2.1925" /score="26.7620012" /energy="-10.6" /TU="U13" /idTUdmin="U10" /TUdmin=1364 /isTUend="FALSE" S_feature 18866..18974 /Source="Nicolas_S_feature" /locus_tag="new_18866_18974" /HighExp="C30, MG 15, MG 10, MG-0.1, MG 25, BMM, ferm, Cold, MG 60, MG-0.2" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S11" promotor_-35 18944..18947 /Source="Nicolas_upshift_promotors" /id="U15" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.61038961038961" /psig="0.998001998001998" /xcortree=2311 /SigmaFactorBS="gaaaaaacccaatttttaataaaaaatgATTTtcaaagcgct aaaaACCGAATAAAATAGTATATAtgcatatgaattattggatttctaggatacaata a" /listShort="S12, pdxS, pdxT, NA, serS" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 18962..18981 /Source="Nicolas_upshift_promotors" /id="U15" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.61038961038961" /psig="0.998001998001998" /xcortree=2311 /SigmaFactorBS="gaaaaaacccaatttttaataaaaaatgATTTtcaaagcgct aaaaACCGAATAAAATAGTATATAtgcatatgaattattggatttctaggatacaata a" /listShort="S12, pdxS, pdxT, NA, serS" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 18976..19061 /Source="Nicolas_S_feature" /locus_tag="new_18976_19061" /HighExp="BMM, MG 25, SMM, MG 15, UNK1, MG 10, GM 150, MG-0.1, MG 150, MG 90" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="0.998, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S12" upshifts 18976 /Source="Nicolas_upshifts" /id="U15" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.61038961038961" /psig="0.998001998001998" /xcortree=2311 /SigmaFactorBS="gaaaaaacccaatttttaataaaaaatgATTTtcaaagcgct aaaaACCGAATAAAATAGTATATAtgcatatgaattattggatttctaggatacaata a" /listShort="S12, pdxS, pdxT, NA, serS" /GFF_Attribute="listLong" CDS 19062..19946 /gene="pdxS" /locus_tag="BSU_00110" /old_locus_tag="BSU00110" /EC_number="4.3.3.6" /EC_number="4.-.-.-" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:14762015, 15771487, 15911615, 16157873, 17144654" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 14762015, 15771487, 15911615, 16157873, 17144654; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="glutamine amidotransferase for pyridoxal phosphate synthesis; pyridoxal 5'-phosphate synthase complex, synthase subunit" /protein_id="NP_387892.1" /db_xref="EnsemblGenomes-Gn:BSU00110" /db_xref="EnsemblGenomes-Tr:CAB11787" /db_xref="GOA:P37527" /db_xref="InterPro:IPR001852" /db_xref="InterPro:IPR011060" /db_xref="InterPro:IPR013785" /db_xref="InterPro:IPR033755" /db_xref="PDB:2NV1" /db_xref="PDB:2NV2" /db_xref="SubtiList:BG10075" /db_xref="UniProtKB/Swiss-Prot:P37527" /translation="MAQTGTERVKRGMAEMQKGGVIMDVINAEQAKIAEEAGAVAVMA LERVPADIRAAGGVARMADPTIVEEVMNAVSIPVMAKARIGHIVEARVLEAMGVDYID ESEVLTPADEEFHLNKNEYTVPFVCGCRDLGEATRRIAEGASMLRTKGEPGTGNIVEA VRHMRKVNAQVRKVVAMSEDELMTEAKNLGAPYELLLQIKKDGKLPVVNFAAGGVATP ADAALMMQLGADGVFVGSGIFKSDNPAKFAKAIVEATTHFTDYKLIAELSKELGTAMK GIEISNLLPEQRMQERGW*" gene 19062..19946 /gene="pdxS" /locus_tag="BSU_00110" /old_locus_tag="BSU00110" S_feature complement(19194..19923) /Source="Nicolas_S_feature" /locus_tag="new_19194_19923_c" /HighExp="S6, S8, S7, S5, S4, C30, S3, BT, C90, Gly" /AntisenseName="pdxS" /AntisenseCor="-0.65390240445415004" /AntisenseRegPval="-33.5" /CDS_PredictionProba="NA" /TUshortSig="SigEF" /TUshortPSig="0.996" /TUlongSig="NA" /TUlongPSig="NA" /label="S13" promotor_-10 complement(19911..19929) /Source="Nicolas_upshift_promotors" /id="U16" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.996003996003996" /psig="0.996003996003996" /xcortree=1195 /SigmaFactorBS="cacctattgttaacatgtcagcagcgctcctatGTTCTTacc agccgcgttcttGCATACGCTGTTCTGGAAGtaagtttgagatttcaatccctttcat t" /listShort="S13" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(19923) /Source="Nicolas_upshifts" /id="U16" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.996003996003996" /psig="0.996003996003996" /xcortree=1195 /SigmaFactorBS="cacctattgttaacatgtcagcagcgctcctatGTTCTTacc agccgcgttcttGCATACGCTGTTCTGGAAGtaagtttgagatttcaatccctttcat t" /listShort="S13" /GFF_Attribute="listLong" promotor_-35 complement(19945..19950) /Source="Nicolas_upshift_promotors" /id="U16" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.996003996003996" /psig="0.996003996003996" /xcortree=1195 /SigmaFactorBS="cacctattgttaacatgtcagcagcgctcctatGTTCTTacc agccgcgttcttGCATACGCTGTTCTGGAAGtaagtttgagatttcaatccctttcat t" /listShort="S13" /GFF_Attribute="listLong" /label="promotor_-35" CDS 19968..20558 /gene="pdxT" /locus_tag="BSU_00120" /old_locus_tag="BSU00120" /EC_number="3.5.1.2" /EC_number="4.3.3.6" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:14585832, 14762015, 15771487, 17144654, 18271580, 26735940" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 14585832, 14762015, 15771487, 17144654, 18271580, 26735940; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="glutamine amidotransferase for pyridoxal phosphate synthesis; pyridoxal 5'-phosphate synthase complex, glutamine amidotransferase subunit PdxT" /protein_id="NP_387893.1" /db_xref="EnsemblGenomes-Gn:BSU00120" /db_xref="EnsemblGenomes-Tr:CAB11788" /db_xref="GOA:P37528" /db_xref="InterPro:IPR002161" /db_xref="InterPro:IPR021196" /db_xref="InterPro:IPR029062" /db_xref="PDB:1R9G" /db_xref="PDB:2NV0" /db_xref="PDB:2NV2" /db_xref="SubtiList:BG10076" /db_xref="UniProtKB/Swiss-Prot:P37528" /translation="MLTIGVLGLQGAVREHIHAIEACGAAGLVVKRPEQLNEVDGLIL PGGESTTMRRLIDTYQFMEPLREFAAQGKPMFGTCAGLIILAKEIAGSDNPHLGLLNV VVERNSFGRQVDSFEADLTIKGLDEPFTGVFIRAPHILEAGENVEVLSEHNGRIVAAK QGQFLGCSFHPELTEDHRVTQLFVEMVEEYKQKALV*" gene 19968..20558 /gene="pdxT" /locus_tag="BSU_00120" /old_locus_tag="BSU00120" misc_RNA 20611..20823 /gene="tboS" /locus_tag="BSU_misc_RNA_1" /product="T-box riboswitch specific of serine tRNA ligase" /experiment="publication(s) with functional evidences, PMID:1317842, 9098041, 12165569, 12547201" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1317842, 9098041, 12165569, 12547201; Product type n: RNA" /function="16.3: Control" gene 20611..20823 /gene="tboS" /locus_tag="BSU_misc_RNA_1" downshifts 20788 /Source="Nicolas_upshifts" /id="D6" /incds=0 /nref=9 /ntot=80 /MaxReadThrough="7.14793" /MaxDrop="4.37654" /score="41.1243331" /energy="-23.3" /TU="U13,U15" /idTUdmin="U13" /TUdmin="-1347" /isTUend="FALSE" CDS 20880..22157 /gene="serS" /locus_tag="BSU_00130" /old_locus_tag="BSU00130" /EC_number="6.1.1.11" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:10546897, 12682299, 14732487" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10546897, 12682299, 14732487; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="seryl-tRNA synthetase" /protein_id="NP_387894.1" /db_xref="EnsemblGenomes-Gn:BSU00130" /db_xref="EnsemblGenomes-Tr:CAB11789" /db_xref="GOA:P37464" /db_xref="InterPro:IPR002314" /db_xref="InterPro:IPR002317" /db_xref="InterPro:IPR006195" /db_xref="InterPro:IPR010978" /db_xref="InterPro:IPR015866" /db_xref="InterPro:IPR033729" /db_xref="SubtiList:BG10077" /db_xref="UniProtKB/Swiss-Prot:P37464" /translation="MLDTKMLRANFQEIKAKLVHKGEDLTDFDKFEALDDRRRELIGK VEELKGKRNEVSQQVAVLKREKKDADHIIKEMREVGEEIKKLDEELRTVEAELDTILL SIPNIPHESVPVGETEDDNVEVRKWGEKPSFAYEPKPHWDIADELGILDFERAAKVTG SRFVFYKGLGARLERALYNFMLDLHVDEYNYTEVIPPYMVNRASMTGTGQLPKFEEDA FKIREEDYFLIPTAEVPITNMHRDEILSGDSLPINYAAFSACFRSEAGSAGRDTRGLI RQHQFNKVELVKFVKPEDSYEELEKLTNQAERVLQLLELPYRVMSMCTGDLGFTAAKK YDIEVWIPSQDTYREISSCSNFEAFQARRANIRFRREAKGKPEHVHTLNGSGLAVGRT VAAILENYQQEDGSVVIPKVLRPYMGNREVMKP*" gene 20880..22157 /gene="serS" /locus_tag="BSU_00130" /old_locus_tag="BSU00130" downshifts 22135 /Source="Nicolas_upshifts" /id="D7" /incds=0 /nref=234 /ntot=255 /MaxReadThrough="0.83411" /MaxDrop="7.38039" /score="17.6549558" /energy="-13.3" /TU="NA" /idTUdmin="U13" /TUdmin=0 /isTUend="TRUE" promotor_-35 22246..22253 /Source="Nicolas_upshift_promotors" /id="U17" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.861138861138861" /psig=1 /xcortree=2413 /SigmaFactorBS="cggcattttcataaaaacaaaaaaagtttttaaaaatgCTTG ACCAcacgagaacatacgTGATATAGTTAGTCTTGTCGatacggaggaatacccaagt c" /listShort="trnSL-Ser1, S14, S15" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 22268..22287 /Source="Nicolas_upshift_promotors" /id="U17" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.861138861138861" /psig=1 /xcortree=2413 /SigmaFactorBS="cggcattttcataaaaacaaaaaaagtttttaaaaatgCTTG ACCAcacgagaacatacgTGATATAGTTAGTCTTGTCGatacggaggaatacccaagt c" /listShort="trnSL-Ser1, S14, S15" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 22268 /Source="Nicolas_upshifts" /id="U17" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.861138861138861" /psig=1 /xcortree=2413 /SigmaFactorBS="cggcattttcataaaaacaaaaaaagtttttaaaaatgCTTG ACCAcacgagaacatacgTGATATAGTTAGTCTTGTCGatacggaggaatacccaagt c" /listShort="trnSL-Ser1, S14, S15" /GFF_Attribute="listLong" tRNA 22292..22384 /gene="trnSL-Ser1" /locus_tag="BSU_tRNA_7" /product="tRNA-Ser" /inference="profile:tRNAscan:1.23" /note="transfer RNA-Ser(UGA); Evidence 2a: Function from experimental evidences in other organisms; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene 22292..22384 /gene="trnSL-Ser1" /locus_tag="BSU_tRNA_7" downshifts 22407 /Source="Nicolas_upshifts" /id="D8" /incds=0 /nref=168 /ntot=196 /MaxReadThrough="5.02201" /MaxDrop="8.36635" /score="29.7083093" /energy="-12.4" /TU="U17" /idTUdmin="U13" /TUdmin=272 /isTUend="FALSE" S_feature 22452..22529 /Source="Nicolas_S_feature" /locus_tag="new_22452_22529" /HighExp="Cold, H2O2, G180, Paraq, Oxctl, C30, G150, G135, BMM, Heat" /AntisenseName="dck" /AntisenseCor="0.61769771609764101" /AntisenseRegPval="-29" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S14" CDS complement(22496..23149) /gene="dck" /locus_tag="BSU_00140" /old_locus_tag="BSU00140" /EC_number="2.7.1.76" /EC_number="2.7.1.74" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:6251049, 11078735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 6251049, 11078735; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="deoxyadenosine/deoxycytidine kinase" /protein_id="NP_387895.1" /db_xref="EnsemblGenomes-Gn:BSU00140" /db_xref="EnsemblGenomes-Tr:CAB11790" /db_xref="GOA:P37529" /db_xref="InterPro:IPR002624" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR031314" /db_xref="SubtiList:BG10078" /db_xref="UniProtKB/Swiss-Prot:P37529" /translation="MKEHHIPKNSIITVAGTVGVGKSTLTKTLAKRLGFKTSLEEVDH NPYLEKFYHDFERWSFHLQIYFLAERFKEQKTIFEAGGGFVQDRSIYEDTGIFAKMHA DKGTMSKVDYKTYTSLFEAMVMTPYFPHPDVLIYLEGDLENILNRIEQRGREMELQTS RSYWEEMHTRYENWISGFNACPVLKLRIEDYDLLNDENSIENIVDQIASVIHDNQKK* " gene complement(22496..23149) /gene="dck" /locus_tag="BSU_00140" /old_locus_tag="BSU00140" promotor_-35 22515..22521 /Source="Nicolas_upshift_promotors" /id="U18" /multdbtbs="-" /comp="M8" /sig="Sig-" /pcomp="0.474525474525474" /psig="0.474525474525474" /xcortree=1189 /SigmaFactorBS="agaaaaagtgaatctcgactgagattcactttttttgattat caTGAATAActgaagcaatttgATCTACAATATTttcaatcgagttttcgtcgttcag a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" downshifts complement(22520) /Source="Nicolas_upshifts" /id="D9" /incds=0 /nref=88 /ntot=213 /MaxReadThrough="1.96668" /MaxDrop="4.49235" /score="14.5948578" /energy="-11" /TU="NA" /idTUdmin="U19" /TUdmin="-1" /isTUend="TRUE" S_feature 22531..23167 /Source="Nicolas_S_feature" /locus_tag="new_22531_23167" /HighExp="G180, G135, Cold, C30, Paraq, H2O2, Oxctl, G150, S5, S6" /AntisenseName="dck" /AntisenseCor="0.15155468296621499" /AntisenseRegPval="-1.9" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S15" upshifts 22531 /Source="Nicolas_upshifts" /id="U18" /multdbtbs="-" /comp="M8" /sig="Sig-" /pcomp="0.474525474525474" /psig="0.474525474525474" /xcortree=1189 /SigmaFactorBS="agaaaaagtgaatctcgactgagattcactttttttgattat caTGAATAActgaagcaatttgATCTACAATATTttcaatcgagttttcgtcgttcag a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 22535..22546 /Source="Nicolas_upshift_promotors" /id="U18" /multdbtbs="-" /comp="M8" /sig="Sig-" /pcomp="0.474525474525474" /psig="0.474525474525474" /xcortree=1189 /SigmaFactorBS="agaaaaagtgaatctcgactgagattcactttttttgattat caTGAATAActgaagcaatttgATCTACAATATTttcaatcgagttttcgtcgttcag a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" CDS complement(23146..23769) /gene="dgk" /locus_tag="BSU_00150" /old_locus_tag="BSU00150" /EC_number="2.7.1.113" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:11078735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11078735; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="deoxyguanosine kinase" /protein_id="NP_387896.1" /db_xref="EnsemblGenomes-Gn:BSU00150" /db_xref="EnsemblGenomes-Tr:CAB11791" /db_xref="GOA:P37530" /db_xref="InterPro:IPR002624" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR031314" /db_xref="SubtiList:BG10079" /db_xref="UniProtKB/Swiss-Prot:P37530" /translation="MNTAPFIAIEGPIGAGKTTLATMLSQKFGFPMINEIVEDNPYLD KFYDNIKEWSFQLEMFFLCHRYKQLEDTSDHFLKKGQPVIADYHIYKNVIFAERTLSP HQLEKYKKIYHLLTDDLPKPNFIIYIKASLPTLLHRIEKRGRPFEKKIETSYLEQLIS DYEVAIKQLQEADPELTVLTVDGDSKDFVLNKSDFERIAAHVKELIV*" gene complement(23146..23769) /gene="dgk" /locus_tag="BSU_00150" /old_locus_tag="BSU00150" promotor_-10 complement(23810..23829) /Source="Nicolas_upshift_promotors" /id="U19" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.948051948051948" /psig=1 /xcortree=2605 /SigmaFactorBS="gtcaaaaagacgtttcgataatttggaaacgtcttttttTCA TGggggcacccaagggtTGTGATACAATATGAAGGTCggtaactgacgcacgtttttc a" /listShort="dgk, dck" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(23828) /Source="Nicolas_upshifts" /id="U19" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.948051948051948" /psig=1 /xcortree=2605 /SigmaFactorBS="gtcaaaaagacgtttcgataatttggaaacgtcttttttTCA TGggggcacccaagggtTGTGATACAATATGAAGGTCggtaactgacgcacgtttttc a" /listShort="dgk, dck" /GFF_Attribute="listLong" promotor_-35 complement(23845..23849) /Source="Nicolas_upshift_promotors" /id="U19" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.948051948051948" /psig=1 /xcortree=2605 /SigmaFactorBS="gtcaaaaagacgtttcgataatttggaaacgtcttttttTCA TGggggcacccaagggtTGTGATACAATATGAAGGTCggtaactgacgcacgtttttc a" /listShort="dgk, dck" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(23868..25151) /gene="sleL" /locus_tag="BSU_00160" /old_locus_tag="BSU00160" /EC_number="3.2.1.-" /function="16.8: Protect" /function="16.13: Shape" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1c: Function from experimental evidences in the studied genus; PubMedId: 11011148, 11737650, 12177332, 10419957, 18456807, 18835992, 19933362, 28333204; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="spore peptidoglycan N-acetylglucosaminidase" /protein_id="NP_387897.1" /db_xref="EnsemblGenomes-Gn:BSU00160" /db_xref="EnsemblGenomes-Tr:CAB11792" /db_xref="GOA:P37531" /db_xref="InterPro:IPR001223" /db_xref="InterPro:IPR011583" /db_xref="InterPro:IPR017853" /db_xref="InterPro:IPR018392" /db_xref="InterPro:IPR036779" /db_xref="SubtiList:BG10080" /db_xref="UniProtKB/Swiss-Prot:P37531" /translation="MVKQGDTLSAIASQYRTTTNDITETNEIPNPDSLVVGQTIVIPI AGQFYDVKRGDTLTSIARQFNTTAAELARVNRIQLNTVLQIGFRLYIPPAPKRDIESN AYLEPRGNQVSENLQQAAREASPYLTYLGAFSFQAQRNGTLVAPPLTNLRSITESQNT TLMMIITNLENQAFSDELGRILLNDETVKRRLLNEIVENARRYGFRDIHFDFEYLRPQ DREAYNQFLREARDLFHREGLEISTALAPKTSATQQGRWYEAHDYRAHGEIVDFVVLM TYEWGYSGGPPQAVSPIGPVRDVIEYALTEMPANKIVMGQNLYGYDWTLPYTAGGTPA RAVSPQQAIVIADQNNASIQYDQTAQAPFFRYTDAENRRHEVWFEDARSIQAKFNLIK ELNLRGISYWKLGLSFPQNWLLLSDQFNVVKKTFR*" gene complement(23868..25151) /gene="sleL" /locus_tag="BSU_00160" /old_locus_tag="BSU00160" downshifts complement(23905) /Source="Nicolas_upshifts" /id="D10" /incds=0 /nref=40 /ntot=61 /MaxReadThrough="1.17442" /MaxDrop="6.30997" /score="3.66560192" /energy="-8.4" /TU="NA" /idTUdmin="U20" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(25182..25200) /Source="Nicolas_upshift_promotors" /id="U20" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1152 /SigmaFactorBS="tttcgcagaaattacgacggaagaacaaattatagaaaaata AACATGatcagcgcttttcttTCATACATTGATAGCGATAtgaaaggaggcgtttttc a" /listShort="yaaH" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(25203) /Source="Nicolas_upshifts" /id="U20" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1152 /SigmaFactorBS="tttcgcagaaattacgacggaagaacaaattatagaaaaata AACATGatcagcgcttttcttTCATACATTGATAGCGATAtgaaaggaggcgtttttc a" /listShort="yaaH" /GFF_Attribute="listLong" promotor_-35 complement(25216..25221) /Source="Nicolas_upshift_promotors" /id="U20" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1152 /SigmaFactorBS="tttcgcagaaattacgacggaagaacaaattatagaaaaata AACATGatcagcgcttttcttTCATACATTGATAGCGATAtgaaaggaggcgtttttc a" /listShort="yaaH" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(25221..25766) /gene="yaaI" /locus_tag="BSU_00170" /old_locus_tag="BSU00170" /EC_number="3.-.-.-" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 2521622; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative amidase (isochorismatase family)" /protein_id="NP_387898.1" /db_xref="EnsemblGenomes-Gn:BSU00170" /db_xref="EnsemblGenomes-Tr:CAB11793" /db_xref="GOA:P37532" /db_xref="InterPro:IPR000868" /db_xref="InterPro:IPR036380" /db_xref="SubtiList:BG10081" /db_xref="UniProtKB/Swiss-Prot:P37532" /translation="MSKADKALLIVDMINNFEFDMGETLAKKTEKIVPHILSLKEHAR QNEWPIIYINDHYGLWQADIKNIQQECTNERSKDIITKIAPVDADYFLIKPKHSAFYE TALHTLLTELQVRHIIITGIAGNICVLFTANDAYMREYSITIPKDCIASNSDEDNEFA LTMMENVLFAEITTEEQIIEK*" gene complement(25221..25766) /gene="yaaI" /locus_tag="BSU_00170" /old_locus_tag="BSU00170" promotor_-35 25632..25636 /Source="Nicolas_upshift_promotors" /id="U21" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.78921078921079" /psig="0.99000999000999" /xcortree=1810 /SigmaFactorBS="taatgatcattgatgtaaataatcggccattcattTTGTCtc gcgtgctcctttAATGATAAAATATGAGGAACgattttttctgtttttttagcgaggg t" /listShort="S16, tadA, S17, scr, S18" /listLong="dnaX, yaaK, recR, yaaL, bofA, S19, rrnA-16S" /label="promotor_-35" promotor_-10 25651..25670 /Source="Nicolas_upshift_promotors" /id="U21" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.78921078921079" /psig="0.99000999000999" /xcortree=1810 /SigmaFactorBS="taatgatcattgatgtaaataatcggccattcattTTGTCtc gcgtgctcctttAATGATAAAATATGAGGAACgattttttctgtttttttagcgaggg t" /listShort="S16, tadA, S17, scr, S18" /listLong="dnaX, yaaK, recR, yaaL, bofA, S19, rrnA-16S" /label="promotor_-10" S_feature 25655..25851 /Source="Nicolas_S_feature" /locus_tag="new_25655_25851" /HighExp="Diami, dia5, H2O2, dia15, T0.30H, T-0.40H, HiOs, T-1.10H, Salt, T0.0H" /AntisenseName="yaaI" /AntisenseCor="9.6546810160837798E-2" /AntisenseRegPval="-0.9" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.99" /TUlongSig="NA" /TUlongPSig="NA" /label="S16" upshifts 25657 /Source="Nicolas_upshifts" /id="U21" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.78921078921079" /psig="0.99000999000999" /xcortree=1810 /SigmaFactorBS="taatgatcattgatgtaaataatcggccattcattTTGTCtc gcgtgctcctttAATGATAAAATATGAGGAACgattttttctgtttttttagcgaggg t" /listShort="S16, tadA, S17, scr, S18" /listLong="dnaX, yaaK, recR, yaaL, bofA, S19, rrnA-16S" promotor_-10 complement(25791..25809) /Source="Nicolas_upshift_promotors" /id="U22" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=248 /SigmaFactorBS="aaagttcatcttgtgtcataaggataagctctcttttcaaAG TTTTTtcattgcctaaaaaGGCTACATATTAACTATAActgaaacggaaaggagactg t" /listShort="yaaI, yaaH" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(25810) /Source="Nicolas_upshifts" /id="U22" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=248 /SigmaFactorBS="aaagttcatcttgtgtcataaggataagctctcttttcaaAG TTTTTtcattgcctaaaaaGGCTACATATTAACTATAActgaaacggaaaggagactg t" /listShort="yaaI, yaaH" /GFF_Attribute="listLong" promotor_-35 complement(25824..25830) /Source="Nicolas_upshift_promotors" /id="U22" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=248 /SigmaFactorBS="aaagttcatcttgtgtcataaggataagctctcttttcaaAG TTTTTtcattgcctaaaaaGGCTACATATTAACTATAActgaaacggaaaggagactg t" /listShort="yaaI, yaaH" /GFF_Attribute="listLong" /label="promotor_-35" CDS 25852..26337 /gene="tadA" /locus_tag="BSU_00180" /old_locus_tag="BSU00180" /EC_number="3.5.4.33" /function="10.3: tRNA and rRNA base modification" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 15677468, 16014871, 16415880, 16700551, 23658230; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="tRNA specific adenosine A34 deaminase" /protein_id="NP_387899.1" /db_xref="EnsemblGenomes-Gn:BSU00180" /db_xref="EnsemblGenomes-Tr:CAB11794" /db_xref="GOA:P21335" /db_xref="InterPro:IPR002125" /db_xref="InterPro:IPR016192" /db_xref="InterPro:IPR016193" /db_xref="InterPro:IPR028883" /db_xref="SubtiList:BG10082" /db_xref="UniProtKB/Swiss-Prot:P21335" /translation="MTQDELYMKEAIKEAKKAEEKGEVPIGAVLVINGEIIARAHNLR ETEQRSIAHAEMLVIDEACKALGTWRLEGATLYVTLEPCPMCAGAVVLSRVEKVVFGA FDPKGGCSGTLMNLLQEERFNHQAEVVSGVLEEECGGMLSAFFRELRKKKKAARKNLS E*" gene 25852..26337 /gene="tadA" /locus_tag="BSU_00180" /old_locus_tag="BSU00180" promotor_-35 26341..26347 /Source="Nicolas_upshift_promotors" /id="U23" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.403596403596404" /psig="0.899100899100899" /xcortree=1436 /SigmaFactorBS="aacttgtctgaatagtacGGTTGCAatttttaggggaaACAG ATATACTTAAGTGTGCatcgtaatagatgcaacataaaatttgatatttattttgccg t" /listShort="S17, scr, S18" /listLong="dnaX, yaaK, recR, yaaL, bofA, S19, rrnA-16S" /label="promotor_-35" promotor_-10 26361..26380 /Source="Nicolas_upshift_promotors" /id="U23" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.403596403596404" /psig="0.899100899100899" /xcortree=1436 /SigmaFactorBS="aacttgtctgaatagtacGGTTGCAatttttaggggaaACAG ATATACTTAAGTGTGCatcgtaatagatgcaacataaaatttgatatttattttgccg t" /listShort="S17, scr, S18" /listLong="dnaX, yaaK, recR, yaaL, bofA, S19, rrnA-16S" /label="promotor_-10" misc_RNA 26379..26732 /gene="scr" /locus_tag="BSU_misc_RNA_2" /product="small cytoplasmic RNA (scRNA, 4.5S RNA), signal recognition particle-like (SRP) component" /experiment="publication(s) with functional evidences, PMID:1372600, 1689715" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1372600, 1689715" gene 26379..26732 /gene="scr" /locus_tag="BSU_misc_RNA_2" S_feature 26383..26532 /Source="Nicolas_S_feature" /locus_tag="new_26383_26532" /HighExp="T1.0H, T5.0H, T1.30H, T3.30H, T3.0H, T2.30H, T4.0H, S8, T-1.10H, Sw" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="0.899, 0.99" /TUlongSig="NA" /TUlongPSig="NA" /label="S17" upshifts 26383 /Source="Nicolas_upshifts" /id="U23" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.403596403596404" /psig="0.899100899100899" /xcortree=1436 /SigmaFactorBS="aacttgtctgaatagtacGGTTGCAatttttaggggaaACAG ATATACTTAAGTGTGCatcgtaatagatgcaacataaaatttgatatttattttgccg t" /listShort="S17, scr, S18" /listLong="dnaX, yaaK, recR, yaaL, bofA, S19, rrnA-16S" S_feature 26636..26731 /Source="Nicolas_S_feature" /locus_tag="new_26636_26731" /HighExp="S8, Sw, B60, B36, T2.30H, T3.30H, T1.0H, BC, T4.0H, T3.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="0.899, 0.99" /TUlongSig="NA" /TUlongPSig="NA" /label="S18" downshifts 26688 /Source="Nicolas_upshifts" /id="D11" /incds=0 /nref=273 /ntot=278 /MaxReadThrough="4.46774" /MaxDrop="8.31255" /score="23.257527" /energy="-10.3" /TU="U21,U23" /idTUdmin="U21" /TUdmin="-89" /isTUend="FALSE" promotor_-35 26752..26755 /Source="Nicolas_upshift_promotors" /id="U24" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.863136863136863" /psig=1 /xcortree=2612 /SigmaFactorBS="attaggtgagttttttgttatgtaaaaagagctTTTGgaatc gaaacaaggTTCATGTATAATGGGAATGAtgaataacggaggagggcaaacccgtgag t" /listShort="dnaX, yaaK, recR, yaaL, bofA" /listLong="S19, rrnA-16S" /label="promotor_-35" promotor_-10 26770..26789 /Source="Nicolas_upshift_promotors" /id="U24" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.863136863136863" /psig=1 /xcortree=2612 /SigmaFactorBS="attaggtgagttttttgttatgtaaaaagagctTTTGgaatc gaaacaaggTTCATGTATAATGGGAATGAtgaataacggaggagggcaaacccgtgag t" /listShort="dnaX, yaaK, recR, yaaL, bofA" /listLong="S19, rrnA-16S" /label="promotor_-10" upshifts 26779 /Source="Nicolas_upshifts" /id="U24" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.863136863136863" /psig=1 /xcortree=2612 /SigmaFactorBS="attaggtgagttttttgttatgtaaaaagagctTTTGgaatc gaaacaaggTTCATGTATAATGGGAATGAtgaataacggaggagggcaaacccgtgag t" /listShort="dnaX, yaaK, recR, yaaL, bofA" /listLong="S19, rrnA-16S" CDS 26814..28505 /gene="dnaX" /locus_tag="BSU_00190" /old_locus_tag="BSU00190" /EC_number="2.7.7.7" /function="16.9: Replicate" /experiment="publication(s) with functional evidences, PMID:9341154, 10844689, 12466528, 12974630, 14757052, 15927750, 25850333, 26786318" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9341154, 10844689, 12466528, 12974630, 14757052, 15927750, 25850333, 26786318; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="DNA polymerase III subunit tau subunit" /protein_id="NP_387900.2" /db_xref="EnsemblGenomes-Gn:BSU00190" /db_xref="EnsemblGenomes-Tr:CAB11795" /db_xref="GOA:P09122" /db_xref="InterPro:IPR001270" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR008921" /db_xref="InterPro:IPR012763" /db_xref="InterPro:IPR022754" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG10083" /db_xref="UniProtKB/Swiss-Prot:P09122" /translation="MSYQALYRVFRPQRFEDVVGQEHITKTLQNALLQKKFSHAYLFS GPRGTGKTSAAKIFAKAVNCEHAPVDEPCNECAACKGITNGSISDVIEIDAASNNGVD EIRDIRDKVKFAPSAVTYKVYIIDEVHMLSIGAFNALLKTLEEPPEHCIFILATTEPH KIPLTIISRCQRFDFKRITSQAIVGRMNKIVDAEQLQVEEGSLEIIASAADGGMRDAL SLLDQAISFSGDILKVEDALLITGAVSQLYIGKLAKSLHDKNVSDALETLNELLQQGK DPAKLIEDMIFYFRDMLLYKTAPGLEGVLEKVKVDETFRELSEQIPAQALYEMIDILN KSHQEMKWTNHPRIFFEVAVVKICQTSHQSAADLPEVDMLMKKIQQLEQEVERLKTTG IKAAAESPKKEAPRVPKGGKSNYKAPVGRIHEILKEATRPDLDLLRNSWGKLLAHLKQ QNKVSHAALLNDSEPVAAGSAAFVLKFKYEIHCKMVAEDNNGVRTNLEQILESMLGKR MDLIGVPEAQWGKIREEFLEDHQQENEGSNEPAEEDPLIAEAKKLVGADLIEIKD*" gene 26814..28505 /gene="dnaX" /locus_tag="BSU_00190" /old_locus_tag="BSU00190" promotor_-35 28346..28353 /Source="Nicolas_upshift_promotors" /id="U25" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.761238761238761" /psig="0.999000999001" /xcortree=1923 /SigmaFactorBS="atgctcggaaaaagaatggatttGATTGGCGttccagaagca caaTGGGGTAAAATAAGAGAAGAatttttagaagatcatcagcaggaaaatgaaggat c" /listShort="yaaK, recR, yaaL, bofA" /listLong="S19, rrnA-16S" /label="promotor_-35" promotor_-10 28368..28387 /Source="Nicolas_upshift_promotors" /id="U25" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.761238761238761" /psig="0.999000999001" /xcortree=1923 /SigmaFactorBS="atgctcggaaaaagaatggatttGATTGGCGttccagaagca caaTGGGGTAAAATAAGAGAAGAatttttagaagatcatcagcaggaaaatgaaggat c" /listShort="yaaK, recR, yaaL, bofA" /listLong="S19, rrnA-16S" /label="promotor_-10" upshifts 28383 /Source="Nicolas_upshifts" /id="U25" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.761238761238761" /psig="0.999000999001" /xcortree=1923 /SigmaFactorBS="atgctcggaaaaagaatggatttGATTGGCGttccagaagca caaTGGGGTAAAATAAGAGAAGAatttttagaagatcatcagcaggaaaatgaaggat c" /listShort="yaaK, recR, yaaL, bofA" /listLong="S19, rrnA-16S" CDS 28529..28852 /gene="ebfC" /locus_tag="BSU_00200" /old_locus_tag="BSU00200" /function="16.9: Replicate" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 16740939, 19208644, 19594923, 20639362, 22333191, 22544270; Product type f : factor" /codon_start=1 /transl_table=11 /product="nucleoid associated protein" /protein_id="NP_387901.1" /db_xref="EnsemblGenomes-Gn:BSU00200" /db_xref="EnsemblGenomes-Tr:CAB11796" /db_xref="GOA:P24281" /db_xref="InterPro:IPR004401" /db_xref="InterPro:IPR036894" /db_xref="SubtiList:BG10084" /db_xref="UniProtKB/Swiss-Prot:P24281" /translation="MRGGMGNMQKMMKQMQKMQKDMAKAQEELAEKVVEGTAGGGMVT VKANGQKEILDVIIKEEVVDPEDIDMLQDLVLAATNEALKKVDEITNETMGQFTKGMN MPGLF*" gene 28529..28852 /gene="ebfC" /locus_tag="BSU_00200" /old_locus_tag="BSU00200" CDS 28867..29463 /gene="recR" /locus_tag="BSU_00210" /old_locus_tag="BSU00210" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:12065426, 24285298, 24891441" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12065426, 24285298, 24891441; Product type f: factor" /codon_start=1 /transl_table=11 /product="recA filament-DNA complex stabilisation factor" /protein_id="NP_387902.1" /db_xref="EnsemblGenomes-Gn:BSU00210" /db_xref="EnsemblGenomes-Tr:CAB11797" /db_xref="GOA:P24277" /db_xref="InterPro:IPR000093" /db_xref="InterPro:IPR006171" /db_xref="InterPro:IPR015967" /db_xref="InterPro:IPR023170" /db_xref="InterPro:IPR023627" /db_xref="InterPro:IPR023628" /db_xref="InterPro:IPR034137" /db_xref="SubtiList:BG10085" /db_xref="UniProtKB/Swiss-Prot:P24277" /translation="MQYPEPISKLIDSFMKLPGIGPKTAVRLAFFVLGMKEDVVLDFA KALVNAKRNLTYCSVCGHITDQDPCYICEDTRRDKSVICVVQDPKDVIAMEKMKEYNG QYHVLHGAISPMDGIGPEDIKIPELLKRLQDDQVTEVILATNPNIEGEATAMYISRLL KPSGIKLSRIAHGLPVGGDLEYADEVTLSKALEGRREL*" gene 28867..29463 /gene="recR" /locus_tag="BSU_00210" /old_locus_tag="BSU00210" CDS 29481..29705 /gene="yaaL" /locus_tag="BSU_00220" /old_locus_tag="BSU00220" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_387903.1" /db_xref="EnsemblGenomes-Gn:BSU00220" /db_xref="EnsemblGenomes-Tr:CAB11798" /db_xref="InterPro:IPR019644" /db_xref="SubtiList:BG10086" /db_xref="UniProtKB/Swiss-Prot:P37533" /translation="MGFLRKKTLRREFDEKLTEQLFKQKEEWNRQKKLVEKSLEPSAE VLYELKVAEAKYFFYLREAKQRNLKISRWK*" gene 29481..29705 /gene="yaaL" /locus_tag="BSU_00220" /old_locus_tag="BSU00220" promotor_-35 29708..29713 /Source="Nicolas_upshift_promotors" /id="U26" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1161 /SigmaFactorBS="aagcgaagcagcgaaatttaaaaatcagccggtggaagtaag tGGTCTAaactcctggatcttcTCATAAGCTTGTACTAGAAcaagcgaaggagatgag a" /listShort="bofA, S19" /listLong="rrnA-16S" /label="promotor_-35" upshifts 29725 /Source="Nicolas_upshifts" /id="U26" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1161 /SigmaFactorBS="aagcgaagcagcgaaatttaaaaatcagccggtggaagtaag tGGTCTAaactcctggatcttcTCATAAGCTTGTACTAGAAcaagcgaaggagatgag a" /listShort="bofA, S19" /listLong="rrnA-16S" promotor_-10 29729..29747 /Source="Nicolas_upshift_promotors" /id="U26" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1161 /SigmaFactorBS="aagcgaagcagcgaaatttaaaaatcagccggtggaagtaag tGGTCTAaactcctggatcttcTCATAAGCTTGTACTAGAAcaagcgaaggagatgag a" /listShort="bofA, S19" /listLong="rrnA-16S" /label="promotor_-10" CDS 29772..30035 /gene="bofA" /locus_tag="BSU_00230" /old_locus_tag="BSU00230" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:15087499, 17557826" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15087499, 17557826; Product type r: regulator" /codon_start=1 /transl_table=11 /product="inhibitor of the pro-sigma(K) processing machinery" /protein_id="NP_387904.2" /db_xref="EnsemblGenomes-Gn:BSU00230" /db_xref="EnsemblGenomes-Tr:CAB11799" /db_xref="GOA:P24282" /db_xref="InterPro:IPR010001" /db_xref="SubtiList:BG10087" /db_xref="UniProtKB/Swiss-Prot:P24282" /translation="MEPIFIIGIILGLVILLFLSGSAAKPLKWIGITAVKFVAGALLL VCVNMFGGSLGIHVPINLVTTAISGILGIPGIAALVVIKQFII*" gene 29772..30035 /gene="bofA" /locus_tag="BSU_00230" /old_locus_tag="BSU00230" promotor_-35 30048..30055 /Source="Nicolas_upshift_promotors" /id="U27" /multdbtbs="SigA" /comp="M17" /sig="SigA" /pcomp="0.999000999001" /psig=1 /xcortree=2620 /SigmaFactorBS="ttaagcaatttatcatttaattgatattatgtATTGACTTag acaactgaaggTGTTATTCTAATATACGTCGctgatgacgaacagcttttttgaaaag a" /listShort="S19, rrnA-16S" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 30069..30088 /Source="Nicolas_upshift_promotors" /id="U27" /multdbtbs="SigA" /comp="M17" /sig="SigA" /pcomp="0.999000999001" /psig=1 /xcortree=2620 /SigmaFactorBS="ttaagcaatttatcatttaattgatattatgtATTGACTTag acaactgaaggTGTTATTCTAATATACGTCGctgatgacgaacagcttttttgaaaag a" /listShort="S19, rrnA-16S" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 30076..30278 /Source="Nicolas_S_feature" /locus_tag="new_30076_30278" /HighExp="LBGstat, Diami, C30, H2O2, Oxctl, HPh, BMM, GM 120, Paraq, T0.30H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigEF" /TUshortPSig="1, 1" /TUlongSig="SigA, SigA, SigA, SigA" /TUlongPSig="0.999, 1, 0.899, 0.99" /label="S19" upshifts 30076 /Source="Nicolas_upshifts" /id="U27" /multdbtbs="SigA" /comp="M17" /sig="SigA" /pcomp="0.999000999001" /psig=1 /xcortree=2620 /SigmaFactorBS="ttaagcaatttatcatttaattgatattatgtATTGACTTag acaactgaaggTGTTATTCTAATATACGTCGctgatgacgaacagcttttttgaaaag a" /listShort="S19, rrnA-16S" /GFF_Attribute="listLong" rRNA 30279..31832 /gene="rrnA-16S" /locus_tag="BSU_rRNA_4" /product="ribosomal RNA-16S" /note="Evidence 1a: Function from experimental evidences in the studied strain; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene 30279..31832 /gene="rrnA-16S" /locus_tag="BSU_rRNA_4" tRNA 31932..32008 /gene="trnA-Ile" /locus_tag="BSU_tRNA_8" /product="tRNA-Ile" /inference="profile:tRNAscan:1.23" /note="transfer RNA-Ile(GAU); Evidence 2a: Function from experimental evidences in other organisms; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene 31932..32008 /gene="trnA-Ile" /locus_tag="BSU_tRNA_8" tRNA 32020..32095 /gene="trnA-Ala" /locus_tag="BSU_tRNA_9" /product="tRNA-Ala" /inference="profile:tRNAscan:1.23" /note="transfer RNA-Ala(UGC); Evidence 2a: Function from experimental evidences in other organisms; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene 32020..32095 /gene="trnA-Ala" /locus_tag="BSU_tRNA_9" rRNA 32177..35103 /gene="rrnA-23S" /locus_tag="BSU_rRNA_5" /product="ribosomal RNA-23S" /note="Evidence 1a: Function from experimental evidences in the studied strain; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene 32177..35103 /gene="rrnA-23S" /locus_tag="BSU_rRNA_5" S_feature 35104..35236 /Source="Nicolas_S_feature" /locus_tag="new_35104_35236" /HighExp="LBGstat, G135, Oxctl, C30, HPh, Paraq, G180, LPh, T0.30H, H2O2" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="NA" /TUshortPSig="NA" /TUlongSig="NA" /TUlongPSig="NA" /label="S20" rRNA 35237..35355 /gene="rrnA-5S" /locus_tag="BSU_rRNA_26" /product="ribosomal RNA-5S" /note="Evidence 1a: Function from experimental evidences in the studied strain; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene 35237..35355 /gene="rrnA-5S" /locus_tag="BSU_rRNA_26" S_feature 35356..35458 /Source="Nicolas_S_feature" /locus_tag="new_35356_35458" /HighExp="Oxctl, Paraq, H2O2, LBGstat, C30, G180, Cold, G135, Heat, BMM" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="NA" /TUshortPSig="NA" /TUlongSig="NA" /TUlongPSig="NA" /label="S21" promotor_-35 35419..35427 /Source="Nicolas_upshift_promotors" /id="U28" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.715284715284715" /psig="0.715284715284715" /xcortree=1057 /SigmaFactorBS="cgagaaaatcaaacaaataCAAACACCGagggcttatatagC CCATATACTGATTTAAAGTttcaaaaaggtctaaatagtgtatacaatatccgtttta a" /listShort="csfB, xpaC, yaaN, S22, yaaO, tmk" /listLong="yaaQ, yaaR, holB, yaaT" /label="promotor_-35" promotor_-10 35441..35460 /Source="Nicolas_upshift_promotors" /id="U28" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.715284715284715" /psig="0.715284715284715" /xcortree=1057 /SigmaFactorBS="cgagaaaatcaaacaaataCAAACACCGagggcttatatagC CCATATACTGATTTAAAGTttcaaaaaggtctaaatagtgtatacaatatccgtttta a" /listShort="csfB, xpaC, yaaN, S22, yaaO, tmk" /listLong="yaaQ, yaaR, holB, yaaT" /label="promotor_-10" upshifts 35460 /Source="Nicolas_upshifts" /id="U28" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.715284715284715" /psig="0.715284715284715" /xcortree=1057 /SigmaFactorBS="cgagaaaatcaaacaaataCAAACACCGagggcttatatagC CCATATACTGATTTAAAGTttcaaaaaggtctaaatagtgtatacaatatccgtttta a" /listShort="csfB, xpaC, yaaN, S22, yaaO, tmk" /listLong="yaaQ, yaaR, holB, yaaT" CDS 35531..35725 /gene="csfB" /locus_tag="BSU_00240" /old_locus_tag="BSU00240" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:8759874, 15044948, 21935351, 26929302" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8759874, 15044948, 21935351, 26929302; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="forespore-specific anti-sigma factor" /protein_id="NP_387905.1" /db_xref="EnsemblGenomes-Gn:BSU00240" /db_xref="EnsemblGenomes-Tr:CAB11800" /db_xref="GOA:P37534" /db_xref="InterPro:IPR019700" /db_xref="SubtiList:BG10088" /db_xref="UniProtKB/Swiss-Prot:P37534" /translation="MDETVKLNHTCVICDQEKNRGIHLYTKFICLDCERKVISTSTSD PDYAFYVKKLKSIHTPPLYS*" gene 35531..35725 /gene="csfB" /locus_tag="BSU_00240" /old_locus_tag="BSU00240" downshifts 35709 /Source="Nicolas_upshifts" /id="D12" /incds=0 /nref=79 /ntot=215 /MaxReadThrough="5.37774" /MaxDrop="4.42494" /score="22.3916007" /energy="-6.7" /TU="U28" /idTUdmin="U27" /TUdmin=3938 /isTUend="FALSE" promotor_-35 35770..35779 /Source="Nicolas_upshift_promotors" /id="U29" /multdbtbs="SigW" /comp="M9" /sig="SigWXY" /pcomp="0.984015984015984" /psig="0.984015984015984" /xcortree=1675 /SigmaFactorBS="tctttttttgtactcttaataataaaaagaagaTGAAACTTG TttaaggattgaACGTAGTAGATAATAAtattaaaactgagtatagacacaggagtcg a" /listShort="xpaC, yaaN, S22, yaaO, tmk, yaaQ, yaaR, holB, yaaT, yabA, yabB, yazA, yabC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 35791..35806 /Source="Nicolas_upshift_promotors" /id="U29" /multdbtbs="SigW" /comp="M9" /sig="SigWXY" /pcomp="0.984015984015984" /psig="0.984015984015984" /xcortree=1675 /SigmaFactorBS="tctttttttgtactcttaataataaaaagaagaTGAAACTTG TttaaggattgaACGTAGTAGATAATAAtattaaaactgagtatagacacaggagtcg a" /listShort="xpaC, yaaN, S22, yaaO, tmk, yaaQ, yaaR, holB, yaaT, yabA, yabB, yazA, yabC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 35797 /Source="Nicolas_upshifts" /id="U29" /multdbtbs="SigW" /comp="M9" /sig="SigWXY" /pcomp="0.984015984015984" /psig="0.984015984015984" /xcortree=1675 /SigmaFactorBS="tctttttttgtactcttaataataaaaagaagaTGAAACTTG TttaaggattgaACGTAGTAGATAATAAtattaaaactgagtatagacacaggagtcg a" /listShort="xpaC, yaaN, S22, yaaO, tmk, yaaQ, yaaR, holB, yaaT, yabA, yabB, yazA, yabC" /GFF_Attribute="listLong" CDS 35845..36459 /gene="xpaC" /locus_tag="BSU_00250" /old_locus_tag="BSU00250" /function="16.11: Scavenge (Catabolism)" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 23155385; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative phosphatase" /protein_id="NP_387906.1" /db_xref="EnsemblGenomes-Gn:BSU00250" /db_xref="EnsemblGenomes-Tr:CAB11801" /db_xref="GOA:P37467" /db_xref="InterPro:IPR018770" /db_xref="SubtiList:BG10089" /db_xref="UniProtKB/Swiss-Prot:P37467" /translation="MQRFFHFLVWSLTSSATFVFIGILSFFGLNQSIFLSIVYGLASG AAVYIAGIWNARRLFLKKHELTGREYAYIKKNLEEARQKMVRLRKALFQAKSIQMFKQ NAEMLRIVRRIYLLTKKEPKRFYQAERFFYQTLDSVVELTEKYAFLSSHPKKSKELSM SLSETRITLTELTKRLEEDLTQAMGDEIDELQFELDAAKHSLKK*" gene 35845..36459 /gene="xpaC" /locus_tag="BSU_00250" /old_locus_tag="BSU00250" CDS 36478..37638 /gene="yaaN" /locus_tag="BSU_00260" /old_locus_tag="BSU00260" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 12533473, 20713661" /codon_start=1 /transl_table=11 /product="putative toxic compound resistance protein" /protein_id="NP_387907.1" /db_xref="EnsemblGenomes-Gn:BSU00260" /db_xref="EnsemblGenomes-Tr:CAB11802" /db_xref="InterPro:IPR008863" /db_xref="SubtiList:BG10090" /db_xref="UniProtKB/Swiss-Prot:P37535" /translation="MNRDQSDLHIDELLADPFGGNIEIPGSEAVKAEKEQVRLVDVLP EENKEKAIQLAGQIDHKNMQSIVLYGSQAQSKLLNFSHDMINHVQKKDVGEIGEILGE LMKKLEQVNPDDLQSKKKGFLARMFGRVSSSLQEVLSKYQKTSVQIDRISLKLEHSKN ALISDNKLLEQLYEKNKEYFAALNVYIAAGELKLEELKTKTIPELKQQAESSDHNQMA VQEVNDLIQFADRLDKRVHDLLLSRQITIQSAPQIRLIQNTNQALAEKIQSSIVTAIP LWKNQVAIALTLLRQRNAVDAQQKVSDTTNELLLKNAELLKTNTIETARANERGLVDI DTLKKVQESLISTLEETLTIQEEGRIKRRQAEEELMMMEGDLKQKLITIKER*" gene 36478..37638 /gene="yaaN" /locus_tag="BSU_00260" /old_locus_tag="BSU00260" S_feature 37639..37719 /Source="Nicolas_S_feature" /locus_tag="new_37639_37719" /HighExp="T0.0H, T-0.40H, T0.30H, T-1.10H, T-1.40H, Salt, T1.0H, G150, Diami, G135" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigWXY, SigK" /TUshortPSig="0.984, 0.715" /TUlongSig="NA" /TUlongPSig="NA" /label="S22" CDS 37720..39162 /gene="yaaO" /locus_tag="BSU_00270" /old_locus_tag="BSU00270" /EC_number="4.1.1.-" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 9723923, 20876533, 24529384; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative decarboxylase" /protein_id="NP_387908.1" /db_xref="EnsemblGenomes-Gn:BSU00270" /db_xref="EnsemblGenomes-Tr:CAB11803" /db_xref="GOA:P37536" /db_xref="InterPro:IPR000310" /db_xref="InterPro:IPR008286" /db_xref="InterPro:IPR015421" /db_xref="InterPro:IPR015422" /db_xref="InterPro:IPR015424" /db_xref="InterPro:IPR036633" /db_xref="SubtiList:BG10091" /db_xref="UniProtKB/Swiss-Prot:P37536" /translation="MNTPLYKALIQHARRNSHSFHVPGHHNGDVFFDDAKSIFDPLLT IDVTELAGLDDLHHPSGVIKEAQELASQLYGSAESFFLVNGTTVGNLAMILSVCEPGD TILVQRNCHKSVFHAVDLSGAEPVYLAPDVDSAMHVPTHVPLGTIKEALEAYPDAKGL VLTNPTYYGHSADLTEIITEAHHYGIPVLVDEAHGAHFILGEPFPVSALKMGADIVVQ SAHKTLPAMTMGSYLHLNSSCRINRDRVAEYLNRLQSSSPSYPIMASLDIARAYVQHI IEEQKLSDILQRIETLKQTFDSLTNAEAVNPANPLIITDPLKLTIRSKRGHSGYTLQS ILERANIFTELADENQVLLVLPLGGKRRINAEIIRSIDEEIEKTPPDQTFVSAEWGVQ PVTVLPYPKKVLHSFKKEYVSFEEAAGRLNAEDIIPYPPGIPMIMAGERITKESVQKL SRLISMKTHVQGNMKIKEKQLLVYIEEEKS*" gene 37720..39162 /gene="yaaO" /locus_tag="BSU_00270" /old_locus_tag="BSU00270" promotor_-35 39082..39088 /Source="Nicolas_upshift_promotors" /id="U30" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.513486513486514" /psig="0.513486513486514" /xcortree=105 /SigmaFactorBS="gaaagtgtgcaaaagctcagccgcttgatcAGCATGAaaacg catgttcaaGGGAATATGAAAATCAAAGagaaacaactacttgtttatatagaagagg a" /listShort="tmk" /listLong="yaaQ, yaaR, holB, yaaT, yabA, yabB, yazA, yabC" /label="promotor_-35" promotor_-10 39103..39121 /Source="Nicolas_upshift_promotors" /id="U30" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.513486513486514" /psig="0.513486513486514" /xcortree=105 /SigmaFactorBS="gaaagtgtgcaaaagctcagccgcttgatcAGCATGAaaacg catgttcaaGGGAATATGAAAATCAAAGagaaacaactacttgtttatatagaagagg a" /listShort="tmk" /listLong="yaaQ, yaaR, holB, yaaT, yabA, yabB, yazA, yabC" /label="promotor_-10" upshifts 39112 /Source="Nicolas_upshifts" /id="U30" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.513486513486514" /psig="0.513486513486514" /xcortree=105 /SigmaFactorBS="gaaagtgtgcaaaagctcagccgcttgatcAGCATGAaaacg catgttcaaGGGAATATGAAAATCAAAGagaaacaactacttgtttatatagaagagg a" /listShort="tmk" /listLong="yaaQ, yaaR, holB, yaaT, yabA, yabB, yazA, yabC" CDS 39159..39797 /gene="tmk" /locus_tag="BSU_00280" /old_locus_tag="BSU00280" /EC_number="2.7.4.9" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:9696781, 12682299, 18523102" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9696781, 12682299, 18523102; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="thymidylate kinase" /protein_id="NP_387909.2" /db_xref="EnsemblGenomes-Gn:BSU00280" /db_xref="EnsemblGenomes-Tr:CAB11804" /db_xref="GOA:P37537" /db_xref="InterPro:IPR018094" /db_xref="InterPro:IPR018095" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG10092" /db_xref="UniProtKB/Swiss-Prot:P37537" /translation="MSGLFITFEGPEGAGKTTVLQEIKNILTAEGLQVMATREPGGID IAEQIREVILNENNILMDPKTEALLYAAARRQHLVEKVKPALEQGFIVLCDRFIDSSL AYQGYARGLGIDEVLSINEFAIGDMMPHVTVYFSIDPEEGLKRIYANGSREKNRLDLE KLDFHTKVQEGYQELMKRFPERFHSVDAGQSKDLVVQDVLKVIDEALKKIQL*" gene 39159..39797 /gene="tmk" /locus_tag="BSU_00280" /old_locus_tag="BSU00280" promotor_-35 39792..39799 /Source="Nicolas_upshift_promotors" /id="U31" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.478521478521479" /psig="0.964035964035964" /xcortree=91 /SigmaFactorBS="tgatcgatgaagcgttgaaaaaaattcaaTTGTGACCtgttt cccaataGTTGATATAATAATGTAAACgagatcacgttgtttccaatctaaaggaggc c" /listShort="yaaQ, yaaR, holB, yaaT, yabA, yabB, yazA, yabC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 39812..39831 /Source="Nicolas_upshift_promotors" /id="U31" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.478521478521479" /psig="0.964035964035964" /xcortree=91 /SigmaFactorBS="tgatcgatgaagcgttgaaaaaaattcaaTTGTGACCtgttt cccaataGTTGATATAATAATGTAAACgagatcacgttgtttccaatctaaaggaggc c" /listShort="yaaQ, yaaR, holB, yaaT, yabA, yabB, yazA, yabC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 39823 /Source="Nicolas_upshifts" /id="U31" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.478521478521479" /psig="0.964035964035964" /xcortree=91 /SigmaFactorBS="tgatcgatgaagcgttgaaaaaaattcaaTTGTGACCtgttt cccaataGTTGATATAATAATGTAAACgagatcacgttgtttccaatctaaaggaggc c" /listShort="yaaQ, yaaR, holB, yaaT, yabA, yabB, yazA, yabC" /GFF_Attribute="listLong" CDS 39871..40200 /gene="darA" /locus_tag="BSU_00290" /old_locus_tag="BSU00290" /experiment="publication(s) with functional evidences, PMID:10913081, 25433025" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10913081, 25433025; Product type rc: receptor" /codon_start=1 /transl_table=11 /product="signal transduction receptor, cyclic di-AMP binding" /protein_id="NP_387910.1" /db_xref="EnsemblGenomes-Gn:BSU00290" /db_xref="EnsemblGenomes-Tr:CAB11805" /db_xref="InterPro:IPR010375" /db_xref="InterPro:IPR011322" /db_xref="InterPro:IPR015867" /db_xref="PDB:4RLE" /db_xref="SubtiList:BG10093" /db_xref="UniProtKB/Swiss-Prot:P37538" /translation="MKLIVAVVQDQDSNRLLKTLTDHNFRVTKLATTGGFLKSGNTTF MIGVEDIRVNKALSLIKENGQKRDQMIAPVSPMGGNADSYVPYPVEVEVGGATVFVLP VDEFHQF*" gene 39871..40200 /gene="darA" /locus_tag="BSU_00290" /old_locus_tag="BSU00290" CDS 40213..40653 /gene="yaaR" /locus_tag="BSU_00300" /old_locus_tag="BSU00300" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 22333191, 22720735" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_387911.1" /db_xref="EnsemblGenomes-Gn:BSU00300" /db_xref="EnsemblGenomes-Tr:CAB11806" /db_xref="InterPro:IPR005585" /db_xref="InterPro:IPR024042" /db_xref="SubtiList:BG10094" /db_xref="UniProtKB/Swiss-Prot:P37539" /translation="MKINKDIRTFIDNKQIPSVKTSEITASFKTSMENQSSKMKLDQL TRLLSDIEAFGKRLTKSRNFKDLARFKGLVKRFVKEAVDSGLSHETSKSFDLYGNSRT LGLVKEIDDKLIQLTEEMMDQEKPAIDLLERIGEIKGLLINLYT*" gene 40213..40653 /gene="yaaR" /locus_tag="BSU_00300" /old_locus_tag="BSU00300" CDS 40665..41654 /gene="holB" /locus_tag="BSU_00310" /old_locus_tag="BSU00310" /EC_number="2.7.7.7" /function="16.9: Replicate" /experiment="publication(s) with functional evidences, PMID:8509334, 12060778, 12682299, 22333191, 23525462" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8509334, 12060778, 12682299, 22333191, 23525462; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="DNA polymerase III clamp loader delta' subunit" /protein_id="NP_387912.1" /db_xref="EnsemblGenomes-Gn:BSU00310" /db_xref="EnsemblGenomes-Tr:CAB11807" /db_xref="GOA:P37540" /db_xref="InterPro:IPR004622" /db_xref="InterPro:IPR015199" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG10095" /db_xref="UniProtKB/Swiss-Prot:P37540" /translation="MAISWKEMNELQPRVMKLLYNSIEKDRLSHAYLFEGKKGTGKLD AALLLAKSFFCLEGGAEPCESCRNCKRIESGNHPDLHLVQPDGLSIKKAQIQALQEEF SKTGLESHKKLYIISHADQMTANAANSLLKFLEEPNKDTMAVLITEQPQRLLDTIISR CQTLPFQPLQPKAIEDRLIEQDVSPHMARLLANMTNNVAEAVELSRNDEFAESRAKVI KLYEVLHQRKGHAFFFIQDQWMPFFKEKTHQEMGLDMLLLIYRDVLSIQIGNEDKLIY QDLFQSIKQHALQSTQQSVTNQILAVLEAKKRLHSNVNVQGLMEHLVLMLQEG*" gene 40665..41654 /gene="holB" /locus_tag="BSU_00310" /old_locus_tag="BSU00310" CDS 41657..42484 /gene="ricT" /locus_tag="BSU_00320" /old_locus_tag="BSU00320" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:12270811, 23490197, 26434553, 27501195, 28295778" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12270811, 23490197, 26434553, 27501195, 28295778; Product type r: regulator" /codon_start=1 /transl_table=11 /product="subunit of a sporulation, competence and biofilmformation regulatory complex of RNaseY (RicAFT complex /FAD / two [4Fe-4S]2+)" /protein_id="NP_387913.1" /db_xref="EnsemblGenomes-Gn:BSU00320" /db_xref="EnsemblGenomes-Tr:CAB11808" /db_xref="GOA:P37541" /db_xref="InterPro:IPR007557" /db_xref="SubtiList:BG10096" /db_xref="UniProtKB/Swiss-Prot:P37541" /translation="MYNVIGVRFKKAGKIYYFDPNGFHIEHDSCVIVETVRGVEYGQV VIANKQVDEHDVVLPLRKVIRVADDRDLLIVEENKQEALSAFDICQKKVIEHGLDMKL VDVEFTFDRNKVIFYFTADGRVDFRELVKDLASIFKTRIELRQIGVRDEAKMLGGIGP CGRMLCCSTFLGDFEPVSIKMAKDQNLSLNPTKISGLCGRLMCCLKYENDEYETAKEQ LPDIGEMITTANGPAKVVGLNILERVLQVELINREKVIEYTWEELLEEGVVSAQTTD* " gene 41657..42484 /gene="ricT" /locus_tag="BSU_00320" /old_locus_tag="BSU00320" CDS 42499..42858 /gene="dnaH" /locus_tag="BSU_00330" /old_locus_tag="BSU00330" /function="16.9: Replicate" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:15927750, 16461910, 19737352, 21895792, 23909787, 28166228" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15927750, 16461910, 19737352, 21895792, 23909787, 28166228; Product type f : factor" /codon_start=1 /transl_table=11 /product="subunit of the DNA replication complex" /protein_id="NP_387914.1" /db_xref="EnsemblGenomes-Gn:BSU00330" /db_xref="EnsemblGenomes-Tr:CAB11809" /db_xref="GOA:P37542" /db_xref="InterPro:IPR010377" /db_xref="PDB:5DOL" /db_xref="SubtiList:BG10097" /db_xref="UniProtKB/Swiss-Prot:P37542" /translation="MDKKELFDTVINLEEQIGSLYRQLGDLKQHIGEMIEENHHLQLE NKHLRKRLDDTTQQIEKFKADKKESKTQKTEQTDIGEGYDNLARLYQEGFHICNVHYG SVRKEDCLFCLSFLNKK*" gene 42499..42858 /gene="dnaH" /locus_tag="BSU_00330" /old_locus_tag="BSU00330" CDS 42917..43660 /gene="trmNF" /locus_tag="BSU_00340" /old_locus_tag="BSU00340" /EC_number="2.1.1.223" /function="10.3: tRNA and rRNA base modification" /function="16.3: Control" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 22905870, 24809820; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase" /protein_id="NP_387915.1" /db_xref="EnsemblGenomes-Gn:BSU00340" /db_xref="EnsemblGenomes-Tr:CAB11810" /db_xref="GOA:P37543" /db_xref="InterPro:IPR007848" /db_xref="InterPro:IPR029063" /db_xref="SubtiList:BG10098" /db_xref="UniProtKB/Swiss-Prot:P37543" /translation="MVSLHDDERLDYLLAEDMKIIQSPTVFAFSLDAVLLSKFAYVPI QKGKIVDLCTGNGIVPLLLSTRSKADILGVEIQERLHDMAVRSVEYNKLDDQIQIIHD DLKNMPEKLGHNRYDVVTCNPPYFKTPKQTEQNMNEHLRIARHEIHCTLEDVISVSSK LLKQGGKAALVHRPGRLLEIFELMKAYQIEPKRVQFVYPKQGKEANTILVEGIKGGRP DLKILPPLFVYDEQNEYTKEIRTILYGDK*" gene 42917..43660 /gene="trmNF" /locus_tag="BSU_00340" /old_locus_tag="BSU00340" CDS 43647..43946 /gene="yazA" /locus_tag="BSU_00350" /old_locus_tag="BSU00350" /function="16.6: Maintain" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 11483577; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative UvrC-Intron-type (URI) endonuclease" /protein_id="NP_387916.1" /db_xref="EnsemblGenomes-Gn:BSU00350" /db_xref="EnsemblGenomes-Tr:CAB11811" /db_xref="InterPro:IPR000305" /db_xref="InterPro:IPR035901" /db_xref="SubtiList:BG12700" /db_xref="UniProtKB/Swiss-Prot:O31414" /translation="METNNHFFYVVKCKDNSWYAGYTNDLHKRVKTHNDGKGAKYTKV RRPVELIFAESFSTKREAMQAEYYFKKLTRKKKELYIEEKRNSKEAVYVKAPNEL*" gene 43647..43946 /gene="yazA" /locus_tag="BSU_00350" /old_locus_tag="BSU00350" CDS 43921..44799 /gene="rsmI" /locus_tag="BSU_00360" /old_locus_tag="BSU00360" /EC_number="2.1.1.198" /function="16.8: Protect" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 16014871, 19965768, 25893373; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="16S rRNA 2'-O-ribose C1402 methyltransferase" /protein_id="NP_387917.1" /db_xref="EnsemblGenomes-Gn:BSU00360" /db_xref="EnsemblGenomes-Tr:CAB11812" /db_xref="GOA:P37544" /db_xref="InterPro:IPR000878" /db_xref="InterPro:IPR008189" /db_xref="InterPro:IPR014776" /db_xref="InterPro:IPR014777" /db_xref="InterPro:IPR018063" /db_xref="InterPro:IPR035996" /db_xref="SubtiList:BG10099" /db_xref="UniProtKB/Swiss-Prot:P37544" /translation="MLRRQMSFNGKSDMGILYLVPTPIGNLEDMTFRAIDTLKSVDAI AAEDTRQTKKLCHVYEIETPLVSYHEHNKESSGHKIIEWLKSGKNIALVSDAGLPTIS DPGAEIVKDFTDIGGYVVPLPGANAALTALIASGIVPQPFFFYGFLNRQKKEKKKELE ALKKRQETIIFYEAPHRLKETLSAMAEILGDREIAVTRELTKKYEEFIRGTISEVIGW ANEDQIRGEFCLVVEGSNNEEVDEEEQWWETLTAKEHVEHYISKGATSKEAIKKAAVD RNVPKREVYDAYHIKQ*" gene 43921..44799 /gene="rsmI" /locus_tag="BSU_00360" /old_locus_tag="BSU00360" downshifts 44772 /Source="Nicolas_upshifts" /id="D13" /incds=0 /nref=23 /ntot=177 /MaxReadThrough="3.33195" /MaxDrop="3.72723" /score="5.97354542" /energy="-10.2" /TU="U29,U31" /idTUdmin="U29" /TUdmin="-23" /isTUend="FALSE" CDS complement(44848..45138) /gene="abrB" /locus_tag="BSU_00370" /old_locus_tag="BSU00370" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:10754235, 10809710, 11101881, 11101897, 16159768, 16223496, 16702211, 25308864, 25381239, 18676675, 22183144, 23196984, 24832089, 24847778, 25288929" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10754235, 10809710, 11101881, 11101897, 16159768, 16223496, 16702211, 25308864, 25381239, 18676675, 22183144, 23196984, 24832089, 24847778, 25288929; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator for transition state genes (AbrB-SurF)" /protein_id="NP_387918.1" /db_xref="EnsemblGenomes-Gn:BSU00370" /db_xref="EnsemblGenomes-Tr:CAB11813" /db_xref="GOA:P08874" /db_xref="InterPro:IPR007159" /db_xref="PDB:1YFB" /db_xref="PDB:1YSF" /db_xref="PDB:1Z0R" /db_xref="PDB:2K1N" /db_xref="PDB:2MJG" /db_xref="PDB:2RO4" /db_xref="SubtiList:BG10100" /db_xref="UniProtKB/Swiss-Prot:P08874" /translation="MFMKSTGIVRKVDELGRVVIPIELRRTLGIAEKDALEIYVDDEK IILKKYKPNMTCQVTGEVSDDNLKLAGGKLVLSKEGAEQIISEIQNQLQNLK*" gene complement(44848..45138) /gene="abrB" /locus_tag="BSU_00370" /old_locus_tag="BSU00370" downshifts complement(44850) /Source="Nicolas_upshifts" /id="D14" /incds=0 /nref=216 /ntot=263 /MaxReadThrough="2.17237" /MaxDrop="7.75729" /score="20.9582436" /energy="-10.2" /TU="U32" /idTUdmin="U32" /TUdmin="-23" /isTUend="FALSE" downshifts 45169 /Source="Nicolas_upshifts" /id="D15" /incds=0 /nref=1 /ntot=15 /MaxReadThrough="2.53543" /MaxDrop="4.31699" /score="13.7153159" /energy="-14.4" /TU="NA" /idTUdmin="U29" /TUdmin=374 /isTUend="FALSE" promotor_-10 complement(45205..45224) /Source="Nicolas_upshift_promotors" /id="U32" /multdbtbs="SigA,SigA" /comp="M19" /sig="SigA" /pcomp="0.608391608391608" /psig=1 /xcortree=2122 /SigmaFactorBS="tataagaactaattcttacaatcaatagtaaacaaaaTGATT GACgattattggaaacCTTGTTATGCTATGAAGGTAaggattttgtcgaataatgacg a" /listShort="abrB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(45222) /Source="Nicolas_upshifts" /id="U32" /multdbtbs="SigA,SigA" /comp="M19" /sig="SigA" /pcomp="0.608391608391608" /psig=1 /xcortree=2122 /SigmaFactorBS="tataagaactaattcttacaatcaatagtaaacaaaaTGATT GACgattattggaaacCTTGTTATGCTATGAAGGTAaggattttgtcgaataatgacg a" /listShort="abrB" /GFF_Attribute="listLong" S_feature complement(45224..45399) /Source="Nicolas_S_feature" /locus_tag="new_45224_45399_c" /HighExp="C30, H2O2, G180, Etha, S0, GM 25, Gly, G135, MG 25, MG-0.2" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.993" /TUlongSig="NA" /TUlongPSig="NA" /label="S23" promotor_-35 complement(45238..45245) /Source="Nicolas_upshift_promotors" /id="U32" /multdbtbs="SigA,SigA" /comp="M19" /sig="SigA" /pcomp="0.608391608391608" /psig=1 /xcortree=2122 /SigmaFactorBS="tataagaactaattcttacaatcaatagtaaacaaaaTGATT GACgattattggaaacCTTGTTATGCTATGAAGGTAaggattttgtcgaataatgacg a" /listShort="abrB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(45395..45414) /Source="Nicolas_upshift_promotors" /id="U33" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.603396603396603" /psig="0.993006993006993" /xcortree=2123 /SigmaFactorBS="aaatctttaatgaaaataaaaaaaGTCTGTTCgtgtcgaatt ttgTCGTATATAATCAAATGAAAtaaaaaactttggttcgaaagtcttgatttaaaag g" /listShort="S23" /listLong="abrB" /label="promotor_-10" upshifts complement(45399) /Source="Nicolas_upshifts" /id="U33" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.603396603396603" /psig="0.993006993006993" /xcortree=2123 /SigmaFactorBS="aaatctttaatgaaaataaaaaaaGTCTGTTCgtgtcgaatt ttgTCGTATATAATCAAATGAAAtaaaaaactttggttcgaaagtcttgatttaaaag g" /listShort="S23" /listLong="abrB" promotor_-35 complement(45428..45435) /Source="Nicolas_upshift_promotors" /id="U33" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.603396603396603" /psig="0.993006993006993" /xcortree=2123 /SigmaFactorBS="aaatctttaatgaaaataaaaaaaGTCTGTTCgtgtcgaatt ttgTCGTATATAATCAAATGAAAtaaaaaactttggttcgaaagtcttgatttaaaag g" /listShort="S23" /listLong="abrB" /label="promotor_-35" promotor_-35 45499..45503 /Source="Nicolas_upshift_promotors" /id="U34" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.803196803196803" /psig="0.999000999001" /xcortree=2569 /SigmaFactorBS="ttttaattattctttttcagggcgtatgtatatatTCTTGat cttaaaggctaaGATGGTATCATAGATAAAGGataaatataaataatattcatatatg a" /listShort="S24, metS, yabD, S26, yabE" /listLong="S27, rnmV, ksgA" /label="promotor_-35" promotor_-10 45518..45537 /Source="Nicolas_upshift_promotors" /id="U34" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.803196803196803" /psig="0.999000999001" /xcortree=2569 /SigmaFactorBS="ttttaattattctttttcagggcgtatgtatatatTCTTGat cttaaaggctaaGATGGTATCATAGATAAAGGataaatataaataatattcatatatg a" /listShort="S24, metS, yabD, S26, yabE" /listLong="S27, rnmV, ksgA" /label="promotor_-10" S_feature 45524..45632 /Source="Nicolas_S_feature" /locus_tag="new_45524_45632" /HighExp="LBGtran, Heat, dia5, dia15, LBGexp, Lbexp, dia0, H2O2, Diami, BMM" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S24" upshifts 45524 /Source="Nicolas_upshifts" /id="U34" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.803196803196803" /psig="0.999000999001" /xcortree=2569 /SigmaFactorBS="ttttaattattctttttcagggcgtatgtatatatTCTTGat cttaaaggctaaGATGGTATCATAGATAAAGGataaatataaataatattcatatatg a" /listShort="S24, metS, yabD, S26, yabE" /listLong="S27, rnmV, ksgA" CDS 45633..47627 /gene="metS" /locus_tag="BSU_00380" /old_locus_tag="BSU00380" /EC_number="6.1.1.10" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1c: Function from experimental evidences in the studied genus; PubMedId: 11233169, 12682299, 12792655; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="methionyl-tRNA synthetase" /protein_id="NP_387919.1" /db_xref="EnsemblGenomes-Gn:BSU00380" /db_xref="EnsemblGenomes-Tr:CAB11814" /db_xref="GOA:P37465" /db_xref="InterPro:IPR001412" /db_xref="InterPro:IPR002547" /db_xref="InterPro:IPR004495" /db_xref="InterPro:IPR009080" /db_xref="InterPro:IPR012340" /db_xref="InterPro:IPR013155" /db_xref="InterPro:IPR014729" /db_xref="InterPro:IPR014758" /db_xref="InterPro:IPR015413" /db_xref="InterPro:IPR023457" /db_xref="InterPro:IPR033911" /db_xref="SubtiList:BG10101" /db_xref="UniProtKB/Swiss-Prot:P37465" /translation="MPQENNTFYITTPIYYPSGKLHIGHAYTTVAGDAMARYKRLKGF DVRYLTGTDEHGQKIQQKAEQENITPQEYVDRAAADIQKLWKQLEISNDDFIRTTEKR HKVVIEKVFQKLLDNGDIYLDEYEGWYSIPDETFYTETQLVDIERNEKGEVIGGKSPD SGHPVELIKEESYFFRMGKYADRLLKYYEENPTFIQPESRKNEMINNFIKPGLEDLAV SRTTFDWGVKVPENPKHVVYVWIDALFNYLTALGYDTENDELYQKYWPADVHLVGKEI VRFHTIYWPIMLMALDLPLPKQVFAHGWLLMKDGKMSKSKGNVVDPVTLIERYGLDEL RYYLLREVPFGSDGVFTPEGFVERINYDLANDLGNLLNRTVAMINKYFDGQIGSYKGA VTEFDHTLTSVAEETVKAYEKAMENMEFSVALSTLWQLISRTNKYIDETAPWVLAKDP AKEEELRSVMYHLAESLRISAVLLQPFLTKTPEKMFEQLGITDESLKAWDSITAFGQL KDTKVQKGEPLFPRLEAEEEIAYIKGKMQGSAPAKEETKEEEPQEVDRLPEITIDQFM DVELRVAEVIEAEPVKKADRLLKLQLDLGFEKRQVVSGIAKHYTPEELVGKKLVCVTN LKPVKLRGELSQGMILAGEADGVLKVVSIDQSLPKGTRIK*" gene 45633..47627 /gene="metS" /locus_tag="BSU_00380" /old_locus_tag="BSU00380" promotor_-10 complement(46381..46400) /Source="Nicolas_upshift_promotors" /id="U35" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.938061938061938" /psig=1 /xcortree=1824 /SigmaFactorBS="cgactaaatgaacatcggcaggccaatatTTTTGataaagct catcattTTCTGTATCATAACCGAGTGccgttaaatagttaaatagtgcgtcaatcca a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(46389) /Source="Nicolas_upshifts" /id="U35" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.938061938061938" /psig=1 /xcortree=1824 /SigmaFactorBS="cgactaaatgaacatcggcaggccaatatTTTTGataaagct catcattTTCTGTATCATAACCGAGTGccgttaaatagttaaatagtgcgtcaatcca a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(46416..46420) /Source="Nicolas_upshift_promotors" /id="U35" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.938061938061938" /psig=1 /xcortree=1824 /SigmaFactorBS="cgactaaatgaacatcggcaggccaatatTTTTGataaagct catcattTTCTGTATCATAACCGAGTGccgttaaatagttaaatagtgcgtcaatcca a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 47611 /Source="Nicolas_upshifts" /id="D16" /incds=0 /nref=18 /ntot=206 /MaxReadThrough="4.8491" /MaxDrop="2.9167" /score="13.7153159" /energy="-14.4" /TU="U34" /idTUdmin="U34" /TUdmin="-2288" /isTUend="FALSE" S_feature complement(47673..50019) /Source="Nicolas_S_feature" /locus_tag="new_47673_50019_c" /HighExp="T0.30H, T1.0H, T1.30H, Salt, C30, T2.0H, T-0.40H, T0.0H, T2.30H, T-1.10H" /AntisenseName="yabE" /AntisenseCor="-0.28154713646185298" /AntisenseRegPval="-5.6" /CDS_PredictionProba="NA" /TUshortSig="SigWXY" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S25" CDS 47706..48473 /gene="dayD" /locus_tag="BSU_00390" /old_locus_tag="BSU00390" /EC_number="3.1.-.-" /function="16.11: Scavenge (Catabolism)" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 10747959, 16014871, 16461678, 19332551; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="D-amino acyl-tRNA deacylase" /protein_id="NP_387920.1" /db_xref="EnsemblGenomes-Gn:BSU00390" /db_xref="EnsemblGenomes-Tr:CAB11815" /db_xref="GOA:P37545" /db_xref="InterPro:IPR001130" /db_xref="InterPro:IPR015991" /db_xref="InterPro:IPR018228" /db_xref="InterPro:IPR032466" /db_xref="SubtiList:BG10102" /db_xref="UniProtKB/Swiss-Prot:P37545" /translation="MLFDTHAHLNAEQYDTDLEEVIERAKAEKVERIVVVGFDRPTIT RAMEMIEEYDFIYAAIGWHPVDAIDMTEEDLAWIKELSAHEKVVAIGEMGLDYHWDKS PKDIQKEVFRNQIALAKEVNLPIIIHNRDATEDVVTILKEEGAEAVGGIMHCFTGSAE VARECMKMNFYLSFGGPVTFKNAKKPKEVVKEIPNDRLLIETDCPFLTPHPFRGKRNE PSYVKYVAEQIAELKEMTFEEIASITTENAKRLFRIN*" gene 47706..48473 /gene="dayD" /locus_tag="BSU_00390" /old_locus_tag="BSU00390" S_feature 48474..48554 /Source="Nicolas_S_feature" /locus_tag="new_48474_48554" /HighExp="Heat, C30, LBGtran, LBGstat, C90, Etha, M40t45, LPhT, MG 15, Gly" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S26" promotor_-35 48531..48536 /Source="Nicolas_upshift_promotors" /id="U36" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.943056943056943" /psig="0.943056943056943" /xcortree=438 /SigmaFactorBS="taagagcttgtcccttacagcgtttttctataaaaGTTCTAc atgctttcttctccTCATAGGATAGGTTTGTCGacaagtctttcttccgtttctcagt g" /listShort="yabE, S27, rnmV, ksgA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 48552..48570 /Source="Nicolas_upshift_promotors" /id="U36" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.943056943056943" /psig="0.943056943056943" /xcortree=438 /SigmaFactorBS="taagagcttgtcccttacagcgtttttctataaaaGTTCTAc atgctttcttctccTCATAGGATAGGTTTGTCGacaagtctttcttccgtttctcagt g" /listShort="yabE, S27, rnmV, ksgA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 48556 /Source="Nicolas_upshifts" /id="U36" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.943056943056943" /psig="0.943056943056943" /xcortree=438 /SigmaFactorBS="taagagcttgtcccttacagcgtttttctataaaaGTTCTAc atgctttcttctccTCATAGGATAGGTTTGTCGacaagtctttcttccgtttctcagt g" /listShort="yabE, S27, rnmV, ksgA" /GFF_Attribute="listLong" promotor_-35 48581..48584 /Source="Nicolas_upshift_promotors" /id="U37" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.705294705294705" /psig="0.843156843156843" /xcortree=440 /SigmaFactorBS="aggataggtttgtcgacaagtctttCTTCcgtttctcagtgt aTTTCAGGATAATGAAGAGGAcactgagcttttgggagaaagagaagggagggttgac a" /listShort="yabE, S27" /listLong="rnmV, ksgA" /label="promotor_-35" promotor_-10 48599..48618 /Source="Nicolas_upshift_promotors" /id="U37" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.705294705294705" /psig="0.843156843156843" /xcortree=440 /SigmaFactorBS="aggataggtttgtcgacaagtctttCTTCcgtttctcagtgt aTTTCAGGATAATGAAGAGGAcactgagcttttgggagaaagagaagggagggttgac a" /listShort="yabE, S27" /listLong="rnmV, ksgA" /label="promotor_-10" upshifts 48616 /Source="Nicolas_upshifts" /id="U37" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.705294705294705" /psig="0.843156843156843" /xcortree=440 /SigmaFactorBS="aggataggtttgtcgacaagtctttCTTCcgtttctcagtgt aTTTCAGGATAATGAAGAGGAcactgagcttttgggagaaagagaagggagggttgac a" /listShort="yabE, S27" /listLong="rnmV, ksgA" CDS 48629..49942 /gene="yabE" /locus_tag="BSU_00400" /old_locus_tag="BSU00400" /function="16.13: Shape" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15774001, 19047346; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative cell wall shaping enzyme" /protein_id="NP_387921.1" /db_xref="EnsemblGenomes-Gn:BSU00400" /db_xref="EnsemblGenomes-Tr:CAB11816" /db_xref="GOA:P37546" /db_xref="InterPro:IPR007137" /db_xref="InterPro:IPR010611" /db_xref="InterPro:IPR011098" /db_xref="InterPro:IPR036908" /db_xref="SubtiList:BG10103" /db_xref="UniProtKB/Swiss-Prot:P37546" /translation="MGEREGRVDSLLDTLYNLSEEKEAFFITQKMKKLFSVKLSKSKV ILVAACLLLAGSGTAYAAHELTKQSVSVSINGKKKHIRTHANTVGDLLETLDIKTRDE DKITPAKQTKITADMDVVYEAAKPVKLTINGEEKTLWSTAKTVGALLDEQDVDVKEQD QIDPAIDTDISKDMKINIEPAFQVTVNDAGKQKKIWTTSTTVADFLKQQKMNIKDEDK IKPALDAKLTKGKADITITRIEKVTDVVEEKIAFDVKKQEDASLEKGKEKVVQKGKEG KLKKHFEVVKENGKEVSRELVKEETAEQSKDKVIAVGTKQSSPKFETVSASGDSKTVV SRSNESTGKVMTVSSTAYTASCSGCSGHTATGVNLKNNPNAKVIAVDPNVIPLGSKVH VEGYGYAIAADTGSAIKGNKIDVFFPEKSSAYRWGNKTVKIKILN*" gene 48629..49942 /gene="yabE" /locus_tag="BSU_00400" /old_locus_tag="BSU00400" promotor_-35 48649..48656 /Source="Nicolas_upshift_promotors" /id="U38" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.926073926073926" /psig=1 /xcortree=2420 /SigmaFactorBS="taatgaagaggacactgagcttttgggagaaagagaagggag GGTTGACAgccttttagatactCTATATAATCTCTCCGAGGAgaaggaggcgtttttc a" /listShort="yabE, S27, rnmV, ksgA" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 48667 /Source="Nicolas_upshifts" /id="U38" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.926073926073926" /psig=1 /xcortree=2420 /SigmaFactorBS="taatgaagaggacactgagcttttgggagaaagagaagggag GGTTGACAgccttttagatactCTATATAATCTCTCCGAGGAgaaggaggcgtttttc a" /listShort="yabE, S27, rnmV, ksgA" /GFF_Attribute="listLong" promotor_-10 48671..48690 /Source="Nicolas_upshift_promotors" /id="U38" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.926073926073926" /psig=1 /xcortree=2420 /SigmaFactorBS="taatgaagaggacactgagcttttgggagaaagagaagggag GGTTGACAgccttttagatactCTATATAATCTCTCCGAGGAgaaggaggcgtttttc a" /listShort="yabE, S27, rnmV, ksgA" /GFF_Attribute="listLong" /label="promotor_-10" downshifts 49903 /Source="Nicolas_upshifts" /id="D17" /incds=0 /nref=87 /ntot=220 /MaxReadThrough="5.02755" /MaxDrop="4.87493" /score="27.529638" /energy="-11.3" /TU="U36,U37,U38" /idTUdmin="U34" /TUdmin=4 /isTUend="TRUE" promotor_-35 49965..49969 /Source="Nicolas_upshift_promotors" /id="U39" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.928071928071928" /psig=1 /xcortree=2584 /SigmaFactorBS="taaaatcttaaattagtatatacttatgtattcagaggGTTT TgcgccctctgtttttTTCGTTATAATAGACAAAGTgcattttctgcttattagacgc t" /listShort="S27, rnmV, ksgA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 49985..50004 /Source="Nicolas_upshift_promotors" /id="U39" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.928071928071928" /psig=1 /xcortree=2584 /SigmaFactorBS="taaaatcttaaattagtatatacttatgtattcagaggGTTT TgcgccctctgtttttTTCGTTATAATAGACAAAGTgcattttctgcttattagacgc t" /listShort="S27, rnmV, ksgA" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 49987..50086 /Source="Nicolas_S_feature" /locus_tag="new_49987_50086" /HighExp="LoTm, H2O2, G180, G135, G150, Paraq, Oxctl, C30, dia15, BMM" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA, SigA, SigEF" /TUshortPSig="1, 1, 0.843, 0.943" /TUlongSig="SigA" /TUlongPSig="0.999" /label="S27" upshifts 49987 /Source="Nicolas_upshifts" /id="U39" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.928071928071928" /psig=1 /xcortree=2584 /SigmaFactorBS="taaaatcttaaattagtatatacttatgtattcagaggGTTT TgcgccctctgtttttTTCGTTATAATAGACAAAGTgcattttctgcttattagacgc t" /listShort="S27, rnmV, ksgA" /GFF_Attribute="listLong" promotor_-10 complement(50011..50026) /Source="Nicolas_upshift_promotors" /id="U40" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=2365 /SigmaFactorBS="ttatttcctccaagacaaaataaaaacttttgtatattcaTG AAACTTTTtcttatatcgaGCGTCTAATAAGCAGAaaatgcactttgtctattataac g" /listShort="S25" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(50027) /Source="Nicolas_upshifts" /id="U40" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=2365 /SigmaFactorBS="ttatttcctccaagacaaaataaaaacttttgtatattcaTG AAACTTTTtcttatatcgaGCGTCTAATAAGCAGAaaatgcactttgtctattataac g" /listShort="S25" /GFF_Attribute="listLong" promotor_-35 complement(50038..50047) /Source="Nicolas_upshift_promotors" /id="U40" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=2365 /SigmaFactorBS="ttatttcctccaagacaaaataaaaacttttgtatattcaTG AAACTTTTtcttatatcgaGCGTCTAATAAGCAGAaaatgcactttgtctattataac g" /listShort="S25" /GFF_Attribute="listLong" /label="promotor_-35" misc_feature 50083..50099 /Source="Nicolas_upshift_promotors" /id="U41" /multdbtbs="-" /comp="M11" /sig="Sig-" /pcomp="0.48051948051948" /psig="0.48051948051948" /xcortree=100 /SigmaFactorBS="aaaaagtttcatgaatatacaaaagtttttattttgtcttgg aggaAATAATGAAAATTAAAGagatcattgtggtcgaggggcgtgacgatacggcccg c" /listShort="rnmV, ksgA" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" CDS 50087..50647 /gene="rnmV" /locus_tag="BSU_00410" /old_locus_tag="BSU00410" /EC_number="3.1.26.8" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:11233981, 11976317, 12794188, 16077031" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11233981, 11976317, 12794188, 16077031; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="ribonuclease M5" /protein_id="NP_387922.1" /db_xref="EnsemblGenomes-Gn:BSU00410" /db_xref="EnsemblGenomes-Tr:CAB11817" /db_xref="GOA:P37547" /db_xref="InterPro:IPR004466" /db_xref="InterPro:IPR006171" /db_xref="InterPro:IPR025156" /db_xref="InterPro:IPR034141" /db_xref="SubtiList:BG10104" /db_xref="UniProtKB/Swiss-Prot:P37547" /translation="MKIKEIIVVEGRDDTARIKLAVDADTIETNGSAIDDHVIDQIRL AQKTRGVIILTDPDFPGEKIRKTISEAVPGCKHAFLPKHLAKPKNKRGIGVEHASVES IRACLENVHEEMEAQPSDISAEDLIHAGLIGGPAAKCRRERLGDLLKIGYTNGKQLQK RLQMFQIKKSDFMSALDTVMREEQNE*" gene 50087..50647 /gene="rnmV" /locus_tag="BSU_00410" /old_locus_tag="BSU00410" upshifts 50097 /Source="Nicolas_upshifts" /id="U41" /multdbtbs="-" /comp="M11" /sig="Sig-" /pcomp="0.48051948051948" /psig="0.48051948051948" /xcortree=100 /SigmaFactorBS="aaaaagtttcatgaatatacaaaagtttttattttgtcttgg aggaAATAATGAAAATTAAAGagatcattgtggtcgaggggcgtgacgatacggcccg c" /listShort="rnmV, ksgA" /GFF_Attribute="listLong" CDS 50640..51518 /gene="rsmA" /locus_tag="BSU_00420" /old_locus_tag="BSU00420" /EC_number="2.1.1.-" /function="16.6: Maintain" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1c: Function from experimental evidences in the studied genus; PubMedId: 99430, 6801425, 11327780, 1690648, 22391551; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="dimethyladenosine 16S ribosomal RNA transferase" /protein_id="NP_387923.1" /db_xref="EnsemblGenomes-Gn:BSU00420" /db_xref="EnsemblGenomes-Tr:CAB11818" /db_xref="GOA:P37468" /db_xref="InterPro:IPR001737" /db_xref="InterPro:IPR011530" /db_xref="InterPro:IPR020596" /db_xref="InterPro:IPR020598" /db_xref="InterPro:IPR023165" /db_xref="InterPro:IPR029063" /db_xref="SubtiList:BG10105" /db_xref="UniProtKB/Swiss-Prot:P37468" /translation="MNKDIATPIRTKEILKKYGFSFKKSLGQNFLIDTNILNRIVDHA EVTEKTGVIEIGPGIGALTEQLAKRAKKVVAFEIDQRLLPILKDTLSPYENVTVIHQD VLKADVKSVIEEQFQDCDEIMVVANLPYYVTTPIIMKLLEEHLPLKGIVVMLQKEVAE RMAADPSSKEYGSLSIAVQFYTEAKTVMIVPKTVFVPQPNVDSAVIRLILRDGPAVDV ENESFFFQLIKASFAQRRKTLLNNLVNNLPEGKAQKSTIEQVLEETNIDGKRRGESLS IEEFAALSNGLYKALF*" gene 50640..51518 /gene="rsmA" /locus_tag="BSU_00420" /old_locus_tag="BSU00420" downshifts 51483 /Source="Nicolas_upshifts" /id="D18" /incds=0 /nref=152 /ntot=229 /MaxReadThrough="3.0815" /MaxDrop="4.58632" /score="20.4155562" /energy="-9.4" /TU="NA" /idTUdmin="U36" /TUdmin=0 /isTUend="TRUE" promotor_-35 51533..51542 /Source="Nicolas_upshift_promotors" /id="U42" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1303 /SigmaFactorBS="ttgtataaagcccttttctaaaagggctttttgttTTGCGCA CCAcatggactgccgcTACATAGGCTAGAGAAGGACctttcattcaatgataagaaaa a" /listShort="S28, yabG" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 51556..51575 /Source="Nicolas_upshift_promotors" /id="U42" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1303 /SigmaFactorBS="ttgtataaagcccttttctaaaagggctttttgttTTGCGCA CCAcatggactgccgcTACATAGGCTAGAGAAGGACctttcattcaatgataagaaaa a" /listShort="S28, yabG" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 51558..51679 /Source="Nicolas_S_feature" /locus_tag="new_51558_51679" /HighExp="S7, S6, S8, BT, S5, B36, G/S, Pyr, B60, Etha" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigK" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S28" upshifts 51558 /Source="Nicolas_upshifts" /id="U42" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1303 /SigmaFactorBS="ttgtataaagcccttttctaaaagggctttttgttTTGCGCA CCAcatggactgccgcTACATAGGCTAGAGAAGGACctttcattcaatgataagaaaa a" /listShort="S28, yabG" /GFF_Attribute="listLong" CDS 51680..52552 /gene="prtG" /locus_tag="BSU_00430" /old_locus_tag="BSU00430" /function="16.13: Shape" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:10714992, 11040425, 16751597, 19060142, 19833771" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10714992, 11040425, 16751597, 19060142, 19833771; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="sporulation-specific protease" /protein_id="NP_387924.1" /db_xref="EnsemblGenomes-Gn:BSU00430" /db_xref="EnsemblGenomes-Tr:CAB11819" /db_xref="GOA:P37548" /db_xref="InterPro:IPR008764" /db_xref="SubtiList:BG10106" /db_xref="UniProtKB/Swiss-Prot:P37548" /translation="MQFQIGDMVARKSYQMDVLFRIIGIEQTSKGNSIAILHGDEVRL IADSDFSDLVAVKKDEQMMRKKKDESRMNESLELLRQDYKLLREKQEYYATSQYQHQE HYFHMPGKVLHLDGDEAYLKKCLNVYKKIGVPVYGIHCHEKKMSASIEVLLDKYRPDI LVITGHDAYSKQKGGIDDLNAYRHSKHFVETVQTARKKIPHLDQLVIFAGACQSHFES LIRAGANFASSPSRVNIHALDPVYIVAKISFTPFMERINVWEVLRNTLTREKGLGGIE TRGVLRIGMPYKSN*" gene 51680..52552 /gene="prtG" /locus_tag="BSU_00430" /old_locus_tag="BSU00430" downshifts 52539 /Source="Nicolas_upshifts" /id="D19" /incds=0 /nref=15 /ntot=32 /MaxReadThrough="2.30424" /MaxDrop="7.1507" /score="26.6672651" /energy="-11.5" /TU="NA" /idTUdmin="U42" /TUdmin=0 /isTUend="TRUE" S_feature 52649..52719 /Source="Nicolas_S_feature" /locus_tag="new_52649_52719" /HighExp="S8, S5, S7, S6, S4, BT, LoTm, G/S, nit, T5.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="NA" /TUshortPSig="NA" /TUlongSig="NA" /TUlongPSig="NA" /label="S29" promotor_-35 52710..52717 /Source="Nicolas_upshift_promotors" /id="U43" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.93906093906094" /psig=1 /xcortree=3089 /SigmaFactorBS="aaataattttattgacaacgtcttattaacgttgatataatt taaatttTATTTGACaaaaatgggctcgTGTTGTACAATAAATGTAGTgaggtggatg c" /listShort="veg, S30, sspF" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 52721 /Source="Nicolas_upshifts" /id="U43" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.93906093906094" /psig=1 /xcortree=3089 /SigmaFactorBS="aaataattttattgacaacgtcttattaacgttgatataatt taaatttTATTTGACaaaaatgggctcgTGTTGTACAATAAATGTAGTgaggtggatg c" /listShort="veg, S30, sspF" /GFF_Attribute="listLong" promotor_-10 52731..52750 /Source="Nicolas_upshift_promotors" /id="U43" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.93906093906094" /psig=1 /xcortree=3089 /SigmaFactorBS="aaataattttattgacaacgtcttattaacgttgatataatt taaatttTATTTGACaaaaatgggctcgTGTTGTACAATAAATGTAGTgaggtggatg c" /listShort="veg, S30, sspF" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-10 complement(52740..52754) /Source="Nicolas_upshift_promotors" /id="U44" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.996003996003996" /psig="0.000999000999001" /xcortree=718 /SigmaFactorBS="attcccatcaagcgatcttttaatatcggacaacgtcttcGC CATtgcatccaCCTCACTACATTTATtgtacaacacgagcccatttttgtcaaataaa a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(52747) /Source="Nicolas_upshifts" /id="U44" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.996003996003996" /psig="0.000999000999001" /xcortree=718 /SigmaFactorBS="attcccatcaagcgatcttttaatatcggacaacgtcttcGC CATtgcatccaCCTCACTACATTTATtgtacaacacgagcccatttttgtcaaataaa a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(52763..52767) /Source="Nicolas_upshift_promotors" /id="U44" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.996003996003996" /psig="0.000999000999001" /xcortree=718 /SigmaFactorBS="attcccatcaagcgatcttttaatatcggacaacgtcttcGC CATtgcatccaCCTCACTACATTTATtgtacaacacgagcccatttttgtcaaataaa a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" CDS 52763..53023 /gene="veg" /locus_tag="BSU_00440" /old_locus_tag="BSU00440" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 12761295, 22720735, 23378512; Producttype ph: phenotype" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_387925.1" /db_xref="EnsemblGenomes-Gn:BSU00440" /db_xref="EnsemblGenomes-Tr:CAB11820" /db_xref="GOA:P37466" /db_xref="InterPro:IPR009366" /db_xref="SubtiList:BG10107" /db_xref="UniProtKB/Swiss-Prot:P37466" /translation="MAKTLSDIKRSLDGNLGKRLTLKANGGRRKTIERSGILAETYPS VFVIQLDQDENSFERVSYSYADILTETVELTFNDDAASSVAF*" gene 52763..53023 /gene="veg" /locus_tag="BSU_00440" /old_locus_tag="BSU00440" downshifts 52935 /Source="Nicolas_upshifts" /id="D20" /incds=1 /nref=4 /ntot=158 /MaxReadThrough="8.09861" /MaxDrop="2.7867" /score="12.4853319" /energy="-9.9" /TU="U43" /idTUdmin="U42" /TUdmin=396 /isTUend="FALSE" downshifts 53022 /Source="Nicolas_upshifts" /id="D21" /incds=0 /nref=191 /ntot=264 /MaxReadThrough="5.88511" /MaxDrop="6.03144" /score="12.4853319" /energy="-9.9" /TU="U43" /idTUdmin="U43" /TUdmin="-331" /isTUend="FALSE" promotor_-35 53088..53094 /Source="Nicolas_upshift_promotors" /id="U45" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp="0.96003996003996" /psig="0.96003996003996" /xcortree=844 /SigmaFactorBS="ttttgttttgcccttttttggtttccaataattttaaCGAAA GTtccatctgatttaACAAAAGATAAAacagtcacatattatcgtgacgtgcacgaat g" /listShort="S30, sspF" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 53108..53119 /Source="Nicolas_upshift_promotors" /id="U45" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp="0.96003996003996" /psig="0.96003996003996" /xcortree=844 /SigmaFactorBS="ttttgttttgcccttttttggtttccaataattttaaCGAAA GTtccatctgatttaACAAAAGATAAAacagtcacatattatcgtgacgtgcacgaat g" /listShort="S30, sspF" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 53111..53182 /Source="Nicolas_S_feature" /locus_tag="new_53111_53182" /HighExp="S8, Cold, S6, S7, ferm, S5, nit, Etha, G135, LoTm" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigGF, SigA" /TUshortPSig="0.96, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S30" upshifts 53111 /Source="Nicolas_upshifts" /id="U45" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp="0.96003996003996" /psig="0.96003996003996" /xcortree=844 /SigmaFactorBS="ttttgttttgcccttttttggtttccaataattttaaCGAAA GTtccatctgatttaACAAAAGATAAAacagtcacatattatcgtgacgtgcacgaat g" /listShort="S30, sspF" /GFF_Attribute="listLong" CDS 53183..53368 /gene="sspF" /locus_tag="BSU_00450" /old_locus_tag="BSU00450" /function="16.5: Explore" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:7959056, 8982008, 11092849" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7959056, 8982008, 11092849; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="small acid-soluble spore protein (alpha/beta-type SASP)" /protein_id="NP_387926.1" /db_xref="EnsemblGenomes-Gn:BSU00450" /db_xref="EnsemblGenomes-Tr:CAB11821" /db_xref="GOA:P37549" /db_xref="InterPro:IPR001448" /db_xref="InterPro:IPR018126" /db_xref="SubtiList:BG10108" /db_xref="UniProtKB/Swiss-Prot:P37549" /translation="MGRRRGVMSDEFKYELAKDLGFYDTVKNGGWGEIRARDAGNMVK RAIEIAEQQMAQNQNNR*" gene 53183..53368 /gene="sspF" /locus_tag="BSU_00450" /old_locus_tag="BSU00450" downshifts 53353 /Source="Nicolas_upshifts" /id="D22" /incds=0 /nref=54 /ntot=153 /MaxReadThrough="2.67408" /MaxDrop="6.21058" /score="38.1065567" /energy="-12.6" /TU="NA" /idTUdmin="U43" /TUdmin=0 /isTUend="TRUE" S_feature complement(53363..55717) /Source="Nicolas_S_feature" /locus_tag="new_53363_55717_c" /HighExp="S5, S4, S6, T5.0H, S3, S8, S7, T4.0H, T3.30H, C30" /AntisenseName="ispE" /AntisenseCor="-0.66604185700913698" /AntisenseRegPval="-35.1" /CDS_PredictionProba="NA" /TUshortSig="SigEF" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S31" promotor_-35 53446..53450 /Source="Nicolas_upshift_promotors" /id="U46" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.745254745254745" /psig=1 /xcortree=2586 /SigmaFactorBS="ttttggatataaatacataatgggctgaatatggataTGTTC atcctgtacttcaaaTGTGATACAATGTTCATACTtatgtttagatggagaagtaggt g" /listShort="ispE, purR, yabJ, S32" /listLong="spoVG" /label="promotor_-35" promotor_-10 53466..53485 /Source="Nicolas_upshift_promotors" /id="U46" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.745254745254745" /psig=1 /xcortree=2586 /SigmaFactorBS="ttttggatataaatacataatgggctgaatatggataTGTTC atcctgtacttcaaaTGTGATACAATGTTCATACTtatgtttagatggagaagtaggt g" /listShort="ispE, purR, yabJ, S32" /listLong="spoVG" /label="promotor_-10" upshifts 53469 /Source="Nicolas_upshifts" /id="U46" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.745254745254745" /psig=1 /xcortree=2586 /SigmaFactorBS="ttttggatataaatacataatgggctgaatatggataTGTTC atcctgtacttcaaaTGTGATACAATGTTCATACTtatgtttagatggagaagtaggt g" /listShort="ispE, purR, yabJ, S32" /listLong="spoVG" CDS 53516..54385 /gene="ispE" /locus_tag="BSU_00460" /old_locus_tag="BSU00460" /EC_number="2.7.1.148" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 11361082, 12682299, 12771135, 17458547, 23840410; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase" /protein_id="NP_387927.1" /db_xref="EnsemblGenomes-Gn:BSU00460" /db_xref="EnsemblGenomes-Tr:CAB11822" /db_xref="GOA:P37550" /db_xref="InterPro:IPR004424" /db_xref="InterPro:IPR006204" /db_xref="InterPro:IPR013750" /db_xref="InterPro:IPR014721" /db_xref="InterPro:IPR020568" /db_xref="InterPro:IPR036554" /db_xref="SubtiList:BG10109" /db_xref="UniProtKB/Swiss-Prot:P37550" /translation="MRILEKAPAKINLSLDVTRKRPDGYHEVEMIMTTIDLADRIELT ELAEDEVRVSSHNRFVPDDQRNLAYQAAKLIKDRYNVKKGVSIMITKVIPVAAGLAGG SSDAAATLRGLNRLWNLNLSAETLAELGAEIGSDVSFCVYGGTALATGRGEKIKHIST PPHCWVILAKPTIGVSTAEVYRALKLDGIEHPDVQGMIEAIEEKSFQKMCSRLGNVLE SVTLDMHPEVAMIKNQMKRFGADAVLMSGSGPTVFGLVQYESKVQRIYNGLRGFCDQV YAVRMIGEQNALD*" gene 53516..54385 /gene="ispE" /locus_tag="BSU_00460" /old_locus_tag="BSU00460" CDS 54441..55298 /gene="purR" /locus_tag="BSU_00470" /old_locus_tag="BSU00470" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:11591660, 12837783, 12837784, 15629952, 16163456, 27329548" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11591660, 12837783, 12837784, 15629952, 16163456, 27329548; Product type r : regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator of the purine biosynthesis operon (PurR-pRpp)" /protein_id="NP_387928.1" /db_xref="EnsemblGenomes-Gn:BSU00470" /db_xref="EnsemblGenomes-Tr:CAB11823" /db_xref="GOA:P37551" /db_xref="InterPro:IPR000836" /db_xref="InterPro:IPR010078" /db_xref="InterPro:IPR015265" /db_xref="InterPro:IPR029057" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="PDB:1O57" /db_xref="PDB:1P4A" /db_xref="SubtiList:BG10110" /db_xref="UniProtKB/Swiss-Prot:P37551" /translation="MKFRRSGRLVDLTNYLLTHPHELIPLTFFSERYESAKSSISEDL TIIKQTFEQQGIGTLLTVPGAAGGVKYIPKMKQAEAEEFVQTLGQSLANPERILPGGY VYLTDILGKPSVLSKVGKLFASVFAEREIDVVMTVATKGIPLAYAAASYLNVPVVIVR KDNKVTEGSTVSINYVSGSSNRIQTMSLAKRSMKTGSNVLIIDDFMKAGGTINGMINL LDEFNANVAGIGVLVEAEGVDERLVDEYMSLLTLSTINMKEKSIEIQNGNFLRFFKDN LLKNGETES*" gene 54441..55298 /gene="purR" /locus_tag="BSU_00470" /old_locus_tag="BSU00470" CDS 55295..55672 /gene="ridA" /locus_tag="BSU_00480" /old_locus_tag="BSU00480" /EC_number="3.5.99.10" /function="16.6: Maintain" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 2113912, 12515541, 14729707, 10557275, 10919400, 10368157, 20562306, 23815688; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="aminoacrylate/iminopropionate hydrolase/deaminase" /protein_id="NP_387929.1" /db_xref="EnsemblGenomes-Gn:BSU00480" /db_xref="EnsemblGenomes-Tr:CAB11824" /db_xref="GOA:P37552" /db_xref="InterPro:IPR006056" /db_xref="InterPro:IPR006175" /db_xref="InterPro:IPR019897" /db_xref="InterPro:IPR035959" /db_xref="PDB:1QD9" /db_xref="SubtiList:BG10111" /db_xref="UniProtKB/Swiss-Prot:P37552" /translation="MTKAVHTKHAPAAIGPYSQGIIVNNMFYSSGQIPLTPSGEMVNG DIKEQTHQVFSNLKAVLEEAGASFETVVKATVFIADMEQFAEVNEVYGQYFDTHKPAR SCVEVARLPKDALVEIEVIALVK*" gene 55295..55672 /gene="ridA" /locus_tag="BSU_00480" /old_locus_tag="BSU00480" downshifts 55662 /Source="Nicolas_upshifts" /id="D23" /incds=0 /nref=172 /ntot=226 /MaxReadThrough="3.8891" /MaxDrop="4.63425" /score="22.9159767" /energy="-12.3" /TU="U46" /idTUdmin="U46" /TUdmin="-155" /isTUend="FALSE" promotor_-10 complement(55706..55724) /Source="Nicolas_upshift_promotors" /id="U47" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1146 /SigmaFactorBS="ttttgaaaaaataggatatagttacacaattagGTCATAaag ctttcatttcggGCATAAGGTAAATAAAAAAgtgatcccggctctcccagaatcactt t" /listShort="S31" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 55707..55815 /Source="Nicolas_S_feature" /locus_tag="new_55707_55815" /HighExp="S8, S7, Etha, B36, LoTm, C30, Sw, B60, G135, G180" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S32" upshifts complement(55718) /Source="Nicolas_upshifts" /id="U47" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1146 /SigmaFactorBS="ttttgaaaaaataggatatagttacacaattagGTCATAaag ctttcatttcggGCATAAGGTAAATAAAAAAgtgatcccggctctcccagaatcactt t" /listShort="S31" /GFF_Attribute="listLong" promotor_-35 complement(55740..55745) /Source="Nicolas_upshift_promotors" /id="U47" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1146 /SigmaFactorBS="ttttgaaaaaataggatatagttacacaattagGTCATAaag ctttcatttcggGCATAAGGTAAATAAAAAAgtgatcccggctctcccagaatcactt t" /listShort="S31" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 55795..55803 /Source="Nicolas_upshift_promotors" /id="U48" /multdbtbs="SigH" /comp="M1" /sig="SigH" /pcomp=1 /psig=1 /xcortree=524 /SigmaFactorBS="actatatcctattttttcaaaaaatattttaaaaacgaGCAG GATTTcagaaaaaatCGTGGAATTGATACACTAAtgcttttatatagggaaaaggtgg t" /listShort="spoVG, S33, gcaD, prs" /listLong="ctc, pth, yabK, S34, mfd, S35, spoVT" /label="promotor_-35" promotor_-10 55814..55832 /Source="Nicolas_upshift_promotors" /id="U48" /multdbtbs="SigH" /comp="M1" /sig="SigH" /pcomp=1 /psig=1 /xcortree=524 /SigmaFactorBS="actatatcctattttttcaaaaaatattttaaaaacgaGCAG GATTTcagaaaaaatCGTGGAATTGATACACTAAtgcttttatatagggaaaaggtgg t" /listShort="spoVG, S33, gcaD, prs" /listLong="ctc, pth, yabK, S34, mfd, S35, spoVT" /label="promotor_-10" upshifts 55817 /Source="Nicolas_upshifts" /id="U48" /multdbtbs="SigH" /comp="M1" /sig="SigH" /pcomp=1 /psig=1 /xcortree=524 /SigmaFactorBS="actatatcctattttttcaaaaaatattttaaaaacgaGCAG GATTTcagaaaaaatCGTGGAATTGATACACTAAtgcttttatatagggaaaaggtgg t" /listShort="spoVG, S33, gcaD, prs" /listLong="ctc, pth, yabK, S34, mfd, S35, spoVT" CDS 55866..56159 /gene="spoVG" /locus_tag="BSU_00490" /old_locus_tag="BSU00490" /function="16.3: Control" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:9733708, 10348850, 10648512, 16428420, 27048798" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9733708, 10348850, 10648512, 16428420, 27048798; Product type r: regulator" /codon_start=1 /transl_table=11 /product="regulator required for spore cortex synthesis (stage V sporulation)" /protein_id="NP_387930.1" /db_xref="EnsemblGenomes-Gn:BSU00490" /db_xref="EnsemblGenomes-Tr:CAB11825" /db_xref="GOA:P28015" /db_xref="InterPro:IPR007170" /db_xref="InterPro:IPR036751" /db_xref="PDB:2IA9" /db_xref="SubtiList:BG10112" /db_xref="UniProtKB/Swiss-Prot:P28015" /translation="MEVTDVRLRRVNTDGRMRAIASITLDHEFVVHDIRVIDGNNGLF VAMPSKRTPDGEFRDITHPINSSTRGKIQDAVLNEYHRLGDTEALEFEEAGAS*" gene 55866..56159 /gene="spoVG" /locus_tag="BSU_00490" /old_locus_tag="BSU00490" downshifts 56148 /Source="Nicolas_upshifts" /id="D24" /incds=0 /nref=263 /ntot=285 /MaxReadThrough="5.11673" /MaxDrop="7.2673" /score="19.392304" /energy="-22.3" /TU="U48" /idTUdmin="U46" /TUdmin=331 /isTUend="FALSE" S_feature 56193..56304 /Source="Nicolas_S_feature" /locus_tag="new_56193_56304" /HighExp="B60, B36, M9-stat, S2, BT, LoTm, Etha, Lbstat, T0.30H, T4.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigH" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S33" promotor_-35 56286..56290 /Source="Nicolas_upshift_promotors" /id="U49" /multdbtbs="SigA" /comp="M16" /sig="SigA" /pcomp="0.895104895104895" /psig="0.996003996003996" /xcortree=2611 /SigmaFactorBS="agttgcactcaatagaaaattcttgcacttcatgaagtctCC TTGaaatcagaagatattTAGGATATATTTTTCTATGGataaaagggatattggaggc c" /listShort="gcaD, prs, ctc, pth, yabK, S34, mfd, S35, spoVT" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 56306..56325 /Source="Nicolas_upshift_promotors" /id="U49" /multdbtbs="SigA" /comp="M16" /sig="SigA" /pcomp="0.895104895104895" /psig="0.996003996003996" /xcortree=2611 /SigmaFactorBS="agttgcactcaatagaaaattcttgcacttcatgaagtctCC TTGaaatcagaagatattTAGGATATATTTTTCTATGGataaaagggatattggaggc c" /listShort="gcaD, prs, ctc, pth, yabK, S34, mfd, S35, spoVT" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 56306 /Source="Nicolas_upshifts" /id="U49" /multdbtbs="SigA" /comp="M16" /sig="SigA" /pcomp="0.895104895104895" /psig="0.996003996003996" /xcortree=2611 /SigmaFactorBS="agttgcactcaatagaaaattcttgcacttcatgaagtctCC TTGaaatcagaagatattTAGGATATATTTTTCTATGGataaaagggatattggaggc c" /listShort="gcaD, prs, ctc, pth, yabK, S34, mfd, S35, spoVT" /GFF_Attribute="listLong" CDS 56352..57722 /gene="glmU" /locus_tag="BSU_00500" /old_locus_tag="BSU00500" /EC_number="2.3.1.157" /EC_number="2.7.7.23" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:1328164, 8522540, 9648743, 11124906, 20495944, 23485416, 24915076" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1328164, 8522540, 9648743, 11124906, 20495944, 23485416, 24915076; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="bifunctional glucosamine-1-phosphate N-acetyltransferase/UDP-N-acetylglucosamine pyrophosphorylase" /protein_id="NP_387931.1" /db_xref="EnsemblGenomes-Gn:BSU00500" /db_xref="EnsemblGenomes-Tr:CAB11826" /db_xref="GOA:P14192" /db_xref="InterPro:IPR001451" /db_xref="InterPro:IPR005835" /db_xref="InterPro:IPR005882" /db_xref="InterPro:IPR011004" /db_xref="InterPro:IPR018357" /db_xref="InterPro:IPR029044" /db_xref="SubtiList:BG10113" /db_xref="UniProtKB/Swiss-Prot:P14192" /translation="MDKRFAVVLAAGQGTRMKSKLYKVLHPVCGKPMVEHVVDEALKL SLSKLVTIVGHGAEEVKKQLGDKSEYALQAKQLGTAHAVKQAQPFLADEKGVTIVICG DTPLLTAETMEQMLKEHTQREAKATILTAVAEDPTGYGRIIRSENGAVQKIVEHKDAS EEERLVTEINTGTYCFDNEALFRAIDQVSNDNAQGEYYLPDVIEILKNEGETVAAYQT GNFQETLGVNDRVALSQAEQFMKERINKRHMQNGVTLIDPMNTYISPDAVIGSDTVIY PGTVIKGEVQIGEDTIIGPHTEIMNSAIGSRTVIKQSVVNHSKVGNDVNIGPFAHIRP DSVIGNEVKIGNFVEIKKTQFGDRSKASHLSYVGDAEVGTDVNLGCGSITVNYDGKNK YLTKIEDGAFIGCNSNLVAPVTVGEGAYVAAGSTVTEDVPGKALAIARARQVNKDDYV KNIHKK*" gene 56352..57722 /gene="glmU" /locus_tag="BSU_00500" /old_locus_tag="BSU00500" downshifts complement(57697) /Source="Nicolas_upshifts" /id="D25" /incds=0 /nref=5 /ntot=84 /MaxReadThrough="2.39379" /MaxDrop="3.65636" /score="-7.65702938" /energy="-13.8" /TU="NA" /idTUdmin="U47" /TUdmin="-4312" /isTUend="FALSE" CDS 57745..58698 /gene="prs" /locus_tag="BSU_00510" /old_locus_tag="BSU00510" /EC_number="2.7.6.1" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:2169413, 3038693, 8522540, 22083279, 25890046" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 2169413, 3038693, 8522540, 22083279, 25890046; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="phosphoribosylpyrophosphate synthetase" /protein_id="NP_387932.1" /db_xref="EnsemblGenomes-Gn:BSU00510" /db_xref="EnsemblGenomes-Tr:CAB11827" /db_xref="GOA:P14193" /db_xref="InterPro:IPR000836" /db_xref="InterPro:IPR000842" /db_xref="InterPro:IPR005946" /db_xref="InterPro:IPR029057" /db_xref="InterPro:IPR029099" /db_xref="PDB:1DKR" /db_xref="PDB:1DKU" /db_xref="PDB:1IBS" /db_xref="SubtiList:BG10114" /db_xref="UniProtKB/Swiss-Prot:P14193" /translation="MSNQYGDKNLKIFSLNSNPELAKEIADIVGVQLGKCSVTRFSDG EVQINIEESIRGCDCYIIQSTSDPVNEHIMELLIMVDALKRASAKTINIVIPYYGYAR QDRKARSREPITAKLFANLLETAGATRVIALDLHAPQIQGFFDIPIDHLMGVPILGEY FEGKNLEDIVIVSPDHGGVTRARKLADRLKAPIAIIDKRRPRPNVAEVMNIVGNIEGK TAILIDDIIDTAGTITLAANALVENGAKEVYACCTHPVLSGPAVERINNSTIKELVVT NSIKLPEEKKIERFKQLSVGPLLAEAIIRVHEQQSVSYLFS*" gene 57745..58698 /gene="prs" /locus_tag="BSU_00510" /old_locus_tag="BSU00510" promotor_-35 58711..58717 /Source="Nicolas_upshift_promotors" /id="U50" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=265 /SigmaFactorBS="agcaatcagtcagctatctgttcagctaaaccatttttcgaG GTTTAAatccttatcgttatGGGTATTGTTTGTAATAGGacaactaaaacgacaagag g" /listShort="ctc, pth, yabK, S34, mfd, S35, spoVT" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 58730 /Source="Nicolas_upshifts" /id="U50" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=265 /SigmaFactorBS="agcaatcagtcagctatctgttcagctaaaccatttttcgaG GTTTAAatccttatcgttatGGGTATTGTTTGTAATAGGacaactaaaacgacaagag g" /listShort="ctc, pth, yabK, S34, mfd, S35, spoVT" /GFF_Attribute="listLong" promotor_-10 58732..58750 /Source="Nicolas_upshift_promotors" /id="U50" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=265 /SigmaFactorBS="agcaatcagtcagctatctgttcagctaaaccatttttcgaG GTTTAAatccttatcgttatGGGTATTGTTTGTAATAGGacaactaaaacgacaagag g" /listShort="ctc, pth, yabK, S34, mfd, S35, spoVT" /GFF_Attribute="listLong" /label="promotor_-10" CDS 58783..59397 /gene="ctc" /locus_tag="BSU_00520" /old_locus_tag="BSU00520" /function="16.2: Construct biomass (Anabolism)" /function="16.6: Maintain" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:8522540, 9669336, 10369900, 12432960, 17198710" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8522540, 9669336, 10369900, 12432960, 17198710; Product type f: factor" /codon_start=1 /transl_table=11 /product="ribosomal protein BL25 (Ctc), binding 5S RNA" /protein_id="NP_387933.1" /db_xref="EnsemblGenomes-Gn:BSU00520" /db_xref="EnsemblGenomes-Tr:CAB11828" /db_xref="GOA:P14194" /db_xref="InterPro:IPR001021" /db_xref="InterPro:IPR011035" /db_xref="InterPro:IPR020056" /db_xref="InterPro:IPR020057" /db_xref="InterPro:IPR029751" /db_xref="InterPro:IPR037121" /db_xref="SubtiList:BG10115" /db_xref="UniProtKB/Swiss-Prot:P14194" /translation="MATLTAKERTDFTRSSLRNIRTSGHVPGIIYGKDTGNKPVSLDS VELIKTLRDEGKNAVITLEVSGEKHSVMVTDLQTDPLKNEITHADFQVVNMSEDIEVE VPIHLTGEAIGVKNGGVLQQPLYALTVKAKPKAIPQTIEADISSLDVNEVLTIADLPA GGDYSFNHESDEVVASILPPQQQEAAEVDEEESADAQPEGENEQ*" gene 58783..59397 /gene="ctc" /locus_tag="BSU_00520" /old_locus_tag="BSU00520" downshifts 59381 /Source="Nicolas_upshifts" /id="D26" /incds=0 /nref=120 /ntot=249 /MaxReadThrough="8.65206" /MaxDrop="5.4784" /score="1.94770319" /energy="-11.2" /TU="U49,U50" /idTUdmin="U48" /TUdmin=682 /isTUend="FALSE" CDS 59504..60070 /gene="pth" /locus_tag="BSU_00530" /old_locus_tag="BSU00530" /EC_number="3.1.1.29" /function="16.8: Protect" /function="16.11: Scavenge (Catabolism)" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:8635758, 12100553, 12682299" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8635758, 12100553, 12682299; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="peptidyl-tRNA hydrolase" /protein_id="NP_387934.1" /db_xref="EnsemblGenomes-Gn:BSU00530" /db_xref="EnsemblGenomes-Tr:CAB11829" /db_xref="GOA:P37470" /db_xref="InterPro:IPR001328" /db_xref="InterPro:IPR018171" /db_xref="InterPro:IPR036416" /db_xref="SubtiList:BG10116" /db_xref="UniProtKB/Swiss-Prot:P37470" /translation="MLVIAGLGNPGKNYENTRHNVGFMVIDQLAKEWNIELNQNKFNG LYGTGFVSGKKVLLVKPLTYMNLSGECLRPLMDYYDVDNEDLTVIYDDLDLPTGKIRL RTKGSAGGHNGIKSLIQHLGTSEFDRIRIGIGRPVNGMKVVDYVLGSFTKEEAPEIEE AVDKSVKACEASLSKPFLEVMNEFNAKV*" gene 59504..60070 /gene="pth" /locus_tag="BSU_00530" /old_locus_tag="BSU00530" misc_feature 59683..59686 /Source="Nicolas_upshift_promotors" /id="U51" /multdbtbs="-" /comp="M11" /sig="Sig-" /pcomp="0.210789210789211" /psig="0.210789210789211" /xcortree=737 /SigmaFactorBS="taacggattatacggaaccggatttgtttccggcaaaaaggt tctacttgttaaACCGcttacatatatgaatttatcaggagaatgtttgcggccttta a" /listShort="yabK, S34, mfd, S35, spoVT" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 59689 /Source="Nicolas_upshifts" /id="U51" /multdbtbs="-" /comp="M11" /sig="Sig-" /pcomp="0.210789210789211" /psig="0.210789210789211" /xcortree=737 /SigmaFactorBS="taacggattatacggaaccggatttgtttccggcaaaaaggt tctacttgttaaACCGcttacatatatgaatttatcaggagaatgtttgcggccttta a" /listShort="yabK, S34, mfd, S35, spoVT" /GFF_Attribute="listLong" CDS 60130..60360 /gene="fin" /locus_tag="BSU_00540" /old_locus_tag="BSU00540" /experiment="publication(s) with functional evidences, PMID:21037003, 28598017" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 21037003, 28598017; Product type f: factor" /codon_start=1 /transl_table=11 /product="protein required for the switch from F to G during sporulation (anti sigma F)" /protein_id="NP_387935.1" /db_xref="EnsemblGenomes-Gn:BSU00540" /db_xref="EnsemblGenomes-Tr:CAB11830" /db_xref="GOA:P37553" /db_xref="InterPro:IPR020115" /db_xref="PDB:5MSL" /db_xref="SubtiList:BG10117" /db_xref="UniProtKB/Swiss-Prot:P37553" /translation="MALHYYCRHCGVKVGSLESSMVSTDSLGFQHLTNEERNDMISYK ENGDVHVLTICEDCQEALDRNPHYHEYHTFIQ*" gene 60130..60360 /gene="fin" /locus_tag="BSU_00540" /old_locus_tag="BSU00540" S_feature 60361..60429 /Source="Nicolas_S_feature" /locus_tag="new_60361_60429" /HighExp="Etha, S5, S4, S7, S8, S6, S3, H2O2, Diami, G180" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="Sig-, SigB, SigA" /TUshortPSig="0.211, 1, 0.996" /TUlongSig="SigH" /TUlongPSig=1 /label="S34" CDS 60430..63963 /gene="mfd" /locus_tag="BSU_00550" /old_locus_tag="BSU00550" /function="16.6: Maintain" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:8594198, 9535092, 11065368, 16950921, 22248542, 25713353, 27399782, 27435260" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8594198, 9535092, 11065368, 16950921, 22248542, 25713353, 27399782, 27435260; Product type f: factor" /codon_start=1 /transl_table=11 /product="transcription-repair coupling factor" /protein_id="NP_387936.1" /db_xref="EnsemblGenomes-Gn:BSU00550" /db_xref="EnsemblGenomes-Tr:CAB11831" /db_xref="GOA:P37474" /db_xref="InterPro:IPR001650" /db_xref="InterPro:IPR003711" /db_xref="InterPro:IPR004576" /db_xref="InterPro:IPR005118" /db_xref="InterPro:IPR011545" /db_xref="InterPro:IPR014001" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR036101" /db_xref="SubtiList:BG10118" /db_xref="UniProtKB/Swiss-Prot:P37474" /translation="MDNIQTFIKESDDFKSIINGLHEGLKEQLLAGLSGSARSVFTSA LANETNKPIFLITHNLYQAQKVTDDLTSLLEDRSVLLYPVNELISSEIAVASPELRAQ RLDVINRLTNGEAPIVVAPVAAIRRMLPPVEVWKSSQMLIQVGHDIEPDQLASRLVEV GYERSDMVSAPGEFSIRGGIIDIYPLTSENPVRIELFDTEVDSIRSFNSDDQRSIETL TSINIGPAKELIIRPEEKARAMEKIDSGLAASLKKLKADKQKEILHANISHDKERLSE GQTDQELVKYLSYFYEKPASLLDYTPDNTLLILDEVSRIHEMEEQLQKEEAEFITNLL EEGKILHDIRLSFSFQKIVAEQKRPLLYYSLFLRHVHHTSPQNIVNVSGRQMQSFHGQ MNVLAGEMERFKKSNFTVVFLGANKERTQKLSSVLADYDIEAAMTDSKKALVQGQVYI MEGELQSGFELPLMKLAVITEEELFKNRVKKKPRKQKLTNAERIKSYSELQIGDYVVH INHGIGKYLGIETLEINGIHKDYLNIHYQGSDKLYVPVEQIDQVQKYVGSEGKEPKLY KLGGSEWKRVKKKVETSVQDIADDLIKLYAEREASKGYAFSPDHEMQREFESAFPYQE TEDQLRSIHEIKKDMERERPMDRLLCGDVGYGKTEVAIRAAFKAIGDGKQVALLVPTT ILAQQHYETIKERFQDYPINIGLLSRFRTRKEANETIKGLKNGTVDIVIGTHRLLSKD VVYKDLGLLIIDEEQRFGVTHKEKIKQIKANVDVLTLTATPIPRTLHMSMLGVRDLSV IETPPENRFPVQTYVVEYNGALVREAIERELARGGQVYFLYNRVEDIERKADEISMLV PDAKVAYAHGKMTENELETVMLSFLEGESDVLVSTTIIETGVDIPNVNTLIVFDADKM GLSQLYQLRGRVGRSNRVAYAYFTYRRDKVLTEVAEKRLQAIKEFTELGSGFKIAMRD LTIRGAGNLLGAQQHGFIDSVGFDLYSQMLKEAIEERKGDTAKTEQFETEIDVELDAY IPETYIQDGKQKIDMYKRFRSVATIEEKNELQDEMIDRFGNYPKEVEYLFTVAEMKVY ARQERVELIKQDKDAVRLTISEEASAEIDGQKLFELGNQYGRQIGLGMEGKKLKISIQ TKGRSADEWLDTVLGMLKGLKDVKKQTISST*" gene 60430..63963 /gene="mfd" /locus_tag="BSU_00550" /old_locus_tag="BSU00550" promotor_-35 63981..63987 /Source="Nicolas_upshift_promotors" /id="U52" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=914 /SigmaFactorBS="agcaaaccatttcatcaacgtaaattttgttactctctggTG TATATtacatttgatgtgACGGATACTAATttcaagcgaggcggaaggtacataaagt a" /listShort="S35, spoVT" /GFF_Attribute="listLong" /label="promotor_-35" S_feature 64001..64098 /Source="Nicolas_S_feature" /locus_tag="new_64001_64098" /HighExp="S5, S7, S8, S6, S4, Etha, S3, H2O2, G135, G180" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigGF, Sig-, SigB, SigA" /TUshortPSig="1, 0.211, 1, 0.996" /TUlongSig="SigH" /TUlongPSig=1 /label="S35" promotor_-10 64001..64012 /Source="Nicolas_upshift_promotors" /id="U52" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=914 /SigmaFactorBS="agcaaaccatttcatcaacgtaaattttgttactctctggTG TATATtacatttgatgtgACGGATACTAATttcaagcgaggcggaaggtacataaagt a" /listShort="S35, spoVT" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 64001 /Source="Nicolas_upshifts" /id="U52" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=914 /SigmaFactorBS="agcaaaccatttcatcaacgtaaattttgttactctctggTG TATATtacatttgatgtgACGGATACTAATttcaagcgaggcggaaggtacataaagt a" /listShort="S35, spoVT" /GFF_Attribute="listLong" CDS 64099..64635 /gene="spoVT" /locus_tag="BSU_00560" /old_locus_tag="BSU00560" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:8755877, 15063493, 15939023, 16159768, 18996130, 22522895, 27790204" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8755877, 15063493, 15939023, 16159768, 18996130, 22522895, 27790204; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator of sporulation / germination" /protein_id="NP_387937.1" /db_xref="EnsemblGenomes-Gn:BSU00560" /db_xref="EnsemblGenomes-Tr:CAB11832" /db_xref="GOA:P37554" /db_xref="InterPro:IPR007159" /db_xref="InterPro:IPR014213" /db_xref="PDB:2RO5" /db_xref="PDB:2W1R" /db_xref="PDB:2W1T" /db_xref="SubtiList:BG10119" /db_xref="UniProtKB/Swiss-Prot:P37554" /translation="MKATGIVRRIDDLGRVVIPKEIRRTLRIREGDPLEIFVDRDGEV ILKKYSPISELGDFAKEYADALYDSLGHSVLICDRDVYIAVSGSSKKDYLNKSISEML ERTMDQRSSVLESDAKSVQLVNGIDEDMNSYTVGPIVANGDPIGAVVIFSKDQTMGEV EHKAVETAAGFLARQMEQ*" gene 64099..64635 /gene="spoVT" /locus_tag="BSU_00560" /old_locus_tag="BSU00560" downshifts 64639 /Source="Nicolas_upshifts" /id="D27" /incds=0 /nref=236 /ntot=260 /MaxReadThrough="1.92082" /MaxDrop="6.20706" /score="-2.69593259" /energy="-11.6" /TU="NA" /idTUdmin="U49" /TUdmin=0 /isTUend="TRUE" misc_feature 64735..64754 /Source="Nicolas_upshift_promotors" /id="U53" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.946053946053946" /psig=1 /xcortree=1839 /SigmaFactorBS="gacgctgttctttttcatgcgtgccgaaaaaggaatccaagg gttgggaTGTGGTATAATAACCTCGTTtttatttgtgccgcggtaatacgtgaaccgt a" /listShort="yabM, yabN, yabO, yabP, yabQ, divIC, yabR" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 64746 /Source="Nicolas_upshifts" /id="U53" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.946053946053946" /psig=1 /xcortree=1839 /SigmaFactorBS="gacgctgttctttttcatgcgtgccgaaaaaggaatccaagg gttgggaTGTGGTATAATAACCTCGTTtttatttgtgccgcggtaatacgtgaaccgt a" /listShort="yabM, yabN, yabO, yabP, yabQ, divIC, yabR" /GFF_Attribute="listLong" CDS 64817..66415 /gene="yabM" /locus_tag="BSU_00570" /old_locus_tag="BSU00570" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative exporter" /protein_id="NP_387938.1" /db_xref="EnsemblGenomes-Gn:BSU00570" /db_xref="EnsemblGenomes-Tr:CAB11833" /db_xref="GOA:P37555" /db_xref="InterPro:IPR002797" /db_xref="InterPro:IPR024923" /db_xref="InterPro:IPR029303" /db_xref="SubtiList:BG10120" /db_xref="UniProtKB/Swiss-Prot:P37555" /translation="MDDSIGVKRHWIWQGAFVLILAGVITKILSAVYRVPFQNIVGDV GFYIYQQVYPFLGIAVMLSTSGFPVIISKLMNDYSEKNHHTILKISALFLSLIGILLF LCLYLGAVPIALFMGDSHLAVLIQVAAYAFLLFPFVALLRGGFQGRHEMLPSALSQMT EQFLRVAVLLGLSFWLVKKGASLYTAGAAAASGSLAGSLVALIILGFFWFKTKRDNQT DRQNENVITTKELTKKLLLYSVTICVSSLLLLFIQLVDALNLYALLSGGEASEEAKCL KGIYDRGQPLLQLGSVFAVSIATSLVPYISMAVKNKELKIMKEKITSSLKLCLVLGTG ASAGLICILKPVNIMLFQNGEGTGALQVFSCSILFASLAVTAAAVLQGAGYTVFPAIA VGAGVAVKWVLNTLLVPRYGIEGASLATAASFAAVAGLNLYQLRQKEWLDKLRGVLIP IIGSALLMSAVLLAYTRLWTFLFPATGRGAAVIESLSAVAIGGAVFIYCMMRLGIFTD EELNSVPFGSKLSKFMRRREQNGG*" gene 64817..66415 /gene="yabM" /locus_tag="BSU_00570" /old_locus_tag="BSU00570" promotor_-35 66286..66293 /Source="Nicolas_upshift_promotors" /id="U54" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.739260739260739" /psig="0.798201798201798" /xcortree=108 /SigmaFactorBS="gattgagagtctttctgctgttgcCATTGGTGgcgcggtgtt tattTATTGTATGATGAGATTGGGaatatttacagatgaagagctgaacagtgtgcca t" /listShort="yabN, yabO, yabP, yabQ" /listLong="divIC, yabR" /label="promotor_-35" promotor_-10 66308..66327 /Source="Nicolas_upshift_promotors" /id="U54" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.739260739260739" /psig="0.798201798201798" /xcortree=108 /SigmaFactorBS="gattgagagtctttctgctgttgcCATTGGTGgcgcggtgtt tattTATTGTATGATGAGATTGGGaatatttacagatgaagagctgaacagtgtgcca t" /listShort="yabN, yabO, yabP, yabQ" /listLong="divIC, yabR" /label="promotor_-10" upshifts 66322 /Source="Nicolas_upshifts" /id="U54" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.739260739260739" /psig="0.798201798201798" /xcortree=108 /SigmaFactorBS="gattgagagtctttctgctgttgcCATTGGTGgcgcggtgtt tattTATTGTATGATGAGATTGGGaatatttacagatgaagagctgaacagtgtgcca t" /listShort="yabN, yabO, yabP, yabQ" /listLong="divIC, yabR" CDS 66405..67874 /gene="yabN" /locus_tag="BSU_00580" /old_locus_tag="BSU00580" /function="16.6: Maintain" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 11178267; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative fusion methylase and nucleotide pyrophosphohydrolase" /protein_id="NP_387939.1" /db_xref="EnsemblGenomes-Gn:BSU00580" /db_xref="EnsemblGenomes-Tr:CAB11834" /db_xref="GOA:P37556" /db_xref="InterPro:IPR000878" /db_xref="InterPro:IPR004518" /db_xref="InterPro:IPR011551" /db_xref="InterPro:IPR014777" /db_xref="InterPro:IPR024180" /db_xref="InterPro:IPR035013" /db_xref="InterPro:IPR035996" /db_xref="SubtiList:BG10121" /db_xref="UniProtKB/Swiss-Prot:P37556" /translation="MAGKITVVGLGAGDMDQLTIGIHKLLTKADTLYVRTKDHPLIEE LEKETKNIRFFDDIYEKHDQFEAVYEEIADILFEAARREDVVYAVPGHPFVAEKTVQL LTERQEKENVQVKVAGGQSFLDATFNVLQIDPIEGFQFVDAGTLSADELELRHHLIIC QVYDQMTASEVKLTLMEKLPDDYEVVIVTAAGSRGEEIRTVPLFELDRNVALNNLTSV YIPPIKEEKLLYHEFSTFRSIIRELRGPNGCPWDKKQTHQSLKQYMIEECYELLEAID EEDTDHMIEELGDVLLQVLLHAQIGEDEGYFTIDDVIKGISEKMVRRHPHVFKDVKVQ DENDVLANWEDIKKAEKNTSESSLLDSVPKTLPALSKAAKLQKKAAKVGFDWEDVSDI WEKVSEEMKEFSSEVSEAPHEHNLKAEFGDILFALVNVARFYKIEPEEALTMTNDKFR RRFSYIEETAKEEGVELADMSLEDMDKLWNEAKETERRS*" gene 66405..67874 /gene="yabN" /locus_tag="BSU_00580" /old_locus_tag="BSU00580" promotor_-35 67046..67053 /Source="Nicolas_upshift_promotors" /id="U55" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2822 /SigmaFactorBS="tggaccgcaatgtcgctttgaacaaCTTAACAAgtgtgtata ttccGCCGATTAAAGAAGAGAAGctgctttatcacgaattctccacgttccgaagcat c" /listShort="yabO, yabP, yabQ, divIC, yabR" /listLong="trnSL-Met1" /label="promotor_-35" promotor_-10 67067..67085 /Source="Nicolas_upshift_promotors" /id="U55" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2822 /SigmaFactorBS="tggaccgcaatgtcgctttgaacaaCTTAACAAgtgtgtata ttccGCCGATTAAAGAAGAGAAGctgctttatcacgaattctccacgttccgaagcat c" /listShort="yabO, yabP, yabQ, divIC, yabR" /listLong="trnSL-Met1" /label="promotor_-10" upshifts 67081 /Source="Nicolas_upshifts" /id="U55" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2822 /SigmaFactorBS="tggaccgcaatgtcgctttgaacaaCTTAACAAgtgtgtata ttccGCCGATTAAAGAAGAGAAGctgctttatcacgaattctccacgttccgaagcat c" /listShort="yabO, yabP, yabQ, divIC, yabR" /listLong="trnSL-Met1" promotor_no_box complement(67469..67569) /Source="Nicolas_upshift_promotors" /id="U56" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.984015984015984" /psig="0.001998001998002" /xcortree=37 /SigmaFactorBS="cgtcttcccagtcaaaaccgaccttcgctgcttttttctgca atttagctgctttcgaaagagctggaagggttttcggtacgctgtctagtaatgatga t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_no_box" upshifts complement(67509) /Source="Nicolas_upshifts" /id="U56" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.984015984015984" /psig="0.001998001998002" /xcortree=37 /SigmaFactorBS="cgtcttcccagtcaaaaccgaccttcgctgcttttttctgca atttagctgctttcgaaagagctggaagggttttcggtacgctgtctagtaatgatga t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" CDS 67877..68137 /gene="hslR" /locus_tag="BSU_00590" /old_locus_tag="BSU00590" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 10675343, 10675344, 19013177; Product type f: factor" /codon_start=1 /transl_table=11 /product="ribosomal RNA binding protein involved in 50S recycling; heat shock protein" /protein_id="NP_387940.1" /db_xref="EnsemblGenomes-Gn:BSU00590" /db_xref="EnsemblGenomes-Tr:CAB11835" /db_xref="GOA:P37557" /db_xref="InterPro:IPR002942" /db_xref="InterPro:IPR025490" /db_xref="InterPro:IPR036986" /db_xref="SubtiList:BG10122" /db_xref="UniProtKB/Swiss-Prot:P37557" /translation="MRLDKFLKVSRLIKRRTLAKEVADQGRISINGNQAKASSDVKPG DELTVRFGQKLVTVQVNELKDTTKKEEAANMYTILKEEKLGE*" gene 67877..68137 /gene="hslR" /locus_tag="BSU_00590" /old_locus_tag="BSU00590" promotor_-35 68142..68147 /Source="Nicolas_upshift_promotors" /id="U57" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp="0.983016983016983" /psig="0.983016983016983" /xcortree=1397 /SigmaFactorBS="aaaaactcggcgaataggcttGTTCTAaaaaaaccccccacc TCATACAATGCAGTAATAAtgctaaaagtatcgaggatatgggggctgaatagatgaa t" /listShort="yabP, yabQ, divIC, yabR" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 68163..68181 /Source="Nicolas_upshift_promotors" /id="U57" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp="0.983016983016983" /psig="0.983016983016983" /xcortree=1397 /SigmaFactorBS="aaaaactcggcgaataggcttGTTCTAaaaaaaccccccacc TCATACAATGCAGTAATAAtgctaaaagtatcgaggatatgggggctgaatagatgaa t" /listShort="yabP, yabQ, divIC, yabR" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 68181 /Source="Nicolas_upshifts" /id="U57" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp="0.983016983016983" /psig="0.983016983016983" /xcortree=1397 /SigmaFactorBS="aaaaactcggcgaataggcttGTTCTAaaaaaaccccccacc TCATACAATGCAGTAATAAtgctaaaagtatcgaggatatgggggctgaatagatgaa t" /listShort="yabP, yabQ, divIC, yabR" /GFF_Attribute="listLong" downshifts complement(68213) /Source="Nicolas_upshifts" /id="D28" /incds=0 /nref=3 /ntot=19 /MaxReadThrough="1.93659" /MaxDrop="3.17193" /score="-0.425236437" /energy="-13.9" /TU="NA" /idTUdmin="U62" /TUdmin=3014 /isTUend="FALSE" CDS 68216..68518 /gene="spcP" /locus_tag="BSU_00600" /old_locus_tag="BSU00600" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:10869437, 11283287, 15231775, 21904870, 22720735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10869437, 11283287, 15231775, 21904870, 22720735; Product type f: factor" /codon_start=1 /transl_table=11 /product="spore protein involved in the shaping of the spore coat" /protein_id="NP_387941.1" /db_xref="EnsemblGenomes-Gn:BSU00600" /db_xref="EnsemblGenomes-Tr:CAB11836" /db_xref="GOA:P37558" /db_xref="InterPro:IPR012504" /db_xref="InterPro:IPR022476" /db_xref="SubtiList:BG10123" /db_xref="UniProtKB/Swiss-Prot:P37558" /translation="MNSYYDQKGSSSVPEQHDVTMKGRKHLDISGVKHVESFDNEEFL LETVMGMLSVRGQNLQMKNLDVEKGIVSIKGRVFDLVYLDEQQGDKAKGFFSKLFK*" gene 68216..68518 /gene="spcP" /locus_tag="BSU_00600" /old_locus_tag="BSU00600" CDS 68515..69150 /gene="spcQ" /locus_tag="BSU_00610" /old_locus_tag="BSU00610" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:10869437, 11283287, 15849754, 16850406" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10869437, 11283287, 15849754, 16850406; Product type f: factor" /codon_start=1 /transl_table=11 /product="membrane protein of the forespore" /protein_id="NP_387942.1" /db_xref="EnsemblGenomes-Gn:BSU00610" /db_xref="EnsemblGenomes-Tr:CAB11837" /db_xref="GOA:P37559" /db_xref="InterPro:IPR014242" /db_xref="InterPro:IPR019074" /db_xref="SubtiList:BG10124" /db_xref="UniProtKB/Swiss-Prot:P37559" /translation="MTLTTQFYTMLAMSGMGLWLGASLDTYRLFVIRAKTARWLLFIH DILFWIMQGLLFFYVLLHVNEGEFRIYIFLAVLLGVATYQSLCKRIYIKILKFVIYLV VSVYQFFKKLIQHVLFRPIVWTCGAIIWLAAFLFKKTYSLIGFLLLCLYKIVMVLCFP IRFIAKQCLKLLPVKMRLTFRRYFEKGAGFLKKKKKLLITIRTTITRFLKR*" gene 68515..69150 /gene="spcQ" /locus_tag="BSU_00610" /old_locus_tag="BSU00610" promotor_-35 69020..69029 /Source="Nicolas_upshift_promotors" /id="U58" /multdbtbs="SigW,SigX" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1706 /SigmaFactorBS="tgtgttttccgatccgttttatcgcgaaacaatgttTGAAAC TTCTtcctgtgaaaatGCGTCTAACTTTTAGAcgttattttgaaaaaggtgcaggatt t" /listShort="divIC, yabR, trnSL-Met1, trnSL-Glu1, S36" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 69042..69057 /Source="Nicolas_upshift_promotors" /id="U58" /multdbtbs="SigW,SigX" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1706 /SigmaFactorBS="tgtgttttccgatccgttttatcgcgaaacaatgttTGAAAC TTCTtcctgtgaaaatGCGTCTAACTTTTAGAcgttattttgaaaaaggtgcaggatt t" /listShort="divIC, yabR, trnSL-Met1, trnSL-Glu1, S36" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 69044 /Source="Nicolas_upshifts" /id="U58" /multdbtbs="SigW,SigX" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1706 /SigmaFactorBS="tgtgttttccgatccgttttatcgcgaaacaatgttTGAAAC TTCTtcctgtgaaaatGCGTCTAACTTTTAGAcgttattttgaaaaaggtgcaggatt t" /listShort="divIC, yabR, trnSL-Met1, trnSL-Glu1, S36" /GFF_Attribute="listLong" promotor_-35 69076..69084 /Source="Nicolas_upshift_promotors" /id="U59" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp=1 /psig=1 /xcortree=532 /SigmaFactorBS="tctaacttttagacgttattttgaaaaaggtGCAGGATTTct caaaaagaAGAAGAAACTATTGATAACcataagaacgaccatcacacggtttttgaag a" /listShort="divIC, yabR" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 69095..69113 /Source="Nicolas_upshift_promotors" /id="U59" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp=1 /psig=1 /xcortree=532 /SigmaFactorBS="tctaacttttagacgttattttgaaaaaggtGCAGGATTTct caaaaagaAGAAGAAACTATTGATAACcataagaacgaccatcacacggtttttgaag a" /listShort="divIC, yabR" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 69105 /Source="Nicolas_upshifts" /id="U59" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp=1 /psig=1 /xcortree=532 /SigmaFactorBS="tctaacttttagacgttattttgaaaaaggtGCAGGATTTct caaaaagaAGAAGAAACTATTGATAACcataagaacgaccatcacacggtttttgaag a" /listShort="divIC, yabR" /GFF_Attribute="listLong" CDS 69168..69545 /gene="divIC" /locus_tag="BSU_00620" /old_locus_tag="BSU00620" /function="16.13: Shape" /function="16.9: Replicate" /experiment="publication(s) with functional evidences, PMID:10844672, 11283287, 11994149, 12682299, 16936019, 20870765, 22720735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10844672, 11283287, 11994149, 12682299, 16936019, 20870765, 22720735; Product type f: factor" /codon_start=1 /transl_table=11 /product="cell-division initiation protein" /protein_id="NP_387943.1" /db_xref="EnsemblGenomes-Gn:BSU00620" /db_xref="EnsemblGenomes-Tr:CAB11838" /db_xref="GOA:P37471" /db_xref="InterPro:IPR007060" /db_xref="SubtiList:BG10125" /db_xref="UniProtKB/Swiss-Prot:P37471" /translation="MNFSRERTITEIQNDYKEQVERQNQLKKRRRKGLYRRLTVFGAL VFLTAIVLASSVWSQTSSLSAKEEKKEQLEKELKSLKTKQTDLKEEISKLKDEDYVTE LARRDLFMSGDGEIIFNVEKKSK*" gene 69168..69545 /gene="divIC" /locus_tag="BSU_00620" /old_locus_tag="BSU00620" CDS 69626..70012 /gene="yabR" /locus_tag="BSU_00630" /old_locus_tag="BSU00630" /EC_number="2.7.-.-" /function="16.11: Scavenge (Catabolism)" /function="16.6: Maintain" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 9862121, 15066026, 16014871, 22720735; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative RNA degradation protein; polyribonucleotide nucleotidyltransferase or phosphorylase" /protein_id="NP_387944.1" /db_xref="EnsemblGenomes-Gn:BSU00630" /db_xref="EnsemblGenomes-Tr:CAB11839" /db_xref="GOA:P37560" /db_xref="InterPro:IPR003029" /db_xref="InterPro:IPR012340" /db_xref="InterPro:IPR022967" /db_xref="SubtiList:BG10126" /db_xref="UniProtKB/Swiss-Prot:P37560" /translation="MSIEVGSKLQGKITGITNFGAFVELPGGSTGLVHISEVADNYVK DINDHLKVGDQVEVKVINVEKDGKIGLSIKKAKDRPQARPRNDFRPKESFEQKMNKFL KDSEDRLSSLKRNTESKRGGRGARRG*" gene 69626..70012 /gene="yabR" /locus_tag="BSU_00630" /old_locus_tag="BSU00630" downshifts 70006 /Source="Nicolas_upshifts" /id="D29" /incds=0 /nref=247 /ntot=274 /MaxReadThrough="3.67278" /MaxDrop="8.3221" /score="23.2738869" /energy="-12.5" /TU="U58" /idTUdmin="U53" /TUdmin="-1" /isTUend="TRUE" promotor_-35 70120..70127 /Source="Nicolas_upshift_promotors" /id="U60" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.85914085914086" /psig=1 /xcortree=2412 /SigmaFactorBS="gaaaattacaacattaaagtttctGTTGACGAaagagacaaa cctTTGTATTATATAACTTGTGCttagaagcacaaaacaatatggcggtgtagctcag c" /listShort="trnSL-Met1, trnSL-Glu1, S36, spoIIE, yabS, yabT" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 70141..70160 /Source="Nicolas_upshift_promotors" /id="U60" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.85914085914086" /psig=1 /xcortree=2412 /SigmaFactorBS="gaaaattacaacattaaagtttctGTTGACGAaagagacaaa cctTTGTATTATATAACTTGTGCttagaagcacaaaacaatatggcggtgtagctcag c" /listShort="trnSL-Met1, trnSL-Glu1, S36, spoIIE, yabS, yabT" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 70156 /Source="Nicolas_upshifts" /id="U60" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.85914085914086" /psig=1 /xcortree=2412 /SigmaFactorBS="gaaaattacaacattaaagtttctGTTGACGAaagagacaaa cctTTGTATTATATAACTTGTGCttagaagcacaaaacaatatggcggtgtagctcag c" /listShort="trnSL-Met1, trnSL-Glu1, S36, spoIIE, yabS, yabT" /GFF_Attribute="listLong" tRNA 70181..70257 /gene="trnSL-Met1" /locus_tag="BSU_tRNA_10" /product="tRNA-Met" /inference="profile:tRNAscan:1.23" /note="methionine transfer RNA (CAU); Evidence 2a: Function from experimental evidences in other organisms; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene 70181..70257 /gene="trnSL-Met1" /locus_tag="BSU_tRNA_10" tRNA 70267..70338 /gene="trnSL-Glu1" /locus_tag="BSU_tRNA_11" /product="tRNA-Glu" /inference="profile:tRNAscan:1.23" /note="glutamate transfer RNA (UUC); Evidence 2a: Functionfrom experimental evidences in other organisms; Producttype n: RNA" /function="16.2: Construct biomass (Anabolism)" gene 70267..70338 /gene="trnSL-Glu1" /locus_tag="BSU_tRNA_11" downshifts 70337 /Source="Nicolas_upshifts" /id="D30" /incds=0 /nref=2 /ntot=58 /MaxReadThrough="4.83761" /MaxDrop="5.55326" /score="25.2769629" /energy="-10.8" /TU="U58,U60" /idTUdmin="U58" /TUdmin="-198" /isTUend="FALSE" S_feature 70382..70493 /Source="Nicolas_S_feature" /locus_tag="new_70382_70493" /HighExp="Cold, G180, C30, G135, G150, Oxctl, Paraq, H2O2, Heat, BMM" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigWXY" /TUshortPSig="1, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S36" misc_feature 70489..70508 /Source="Nicolas_upshift_promotors" /id="U61" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.632367632367632" /psig="0.99000999000999" /xcortree=442 /SigmaFactorBS="cgtcgaagatttctttggtattgttaccttcttttgacaaaa tcctatctgtgcTTTCGCTATAATGACAGGCAacgaatataacaggtgggagatgaga g" /listShort="spoIIE, yabS, yabT, tilS" /listLong="hprT, S38, ftsH" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 70495 /Source="Nicolas_upshifts" /id="U61" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.632367632367632" /psig="0.99000999000999" /xcortree=442 /SigmaFactorBS="cgtcgaagatttctttggtattgttaccttcttttgacaaaa tcctatctgtgcTTTCGCTATAATGACAGGCAacgaatataacaggtgggagatgaga g" /listShort="spoIIE, yabS, yabT, tilS" /listLong="hprT, S38, ftsH" CDS 70538..73021 /gene="spoIIE" /locus_tag="BSU_00640" /old_locus_tag="BSU00640" /EC_number="3.1.3.16" /function="16.3: Control" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:10747015, 12180929, 15126482, 15866939, 15978076, 28358838" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10747015, 12180929, 15126482, 15866939, 15978076, 28358838; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="SpoIIAA-phosphate serine phosphatase" /protein_id="NP_387945.1" /db_xref="EnsemblGenomes-Gn:BSU00640" /db_xref="EnsemblGenomes-Tr:CAB11840" /db_xref="GOA:P37475" /db_xref="InterPro:IPR001932" /db_xref="InterPro:IPR014221" /db_xref="InterPro:IPR036457" /db_xref="PDB:3T91" /db_xref="PDB:3T9Q" /db_xref="PDB:5UCG" /db_xref="SubtiList:BG10127" /db_xref="UniProtKB/Swiss-Prot:P37475" /translation="MEKAERRVNGPMAGQALEKLQSFFNRGTKLVTHHLHSLFFYKGF IYVVIGFLLGRAFILSEVLPFALPFFGAMLLIRRDKAFYAVLAVLAGALTISPKHSLL ILAALLAFFVFSKVAAFITDDRVKALPIVVFFSMAAARAGFVYAQNGVFTTYDYVMAI VEAGLSFILTLIFLQSLPIFTVKKVKQSLKIEEIICFMILIASVLTGLAGLSYQGMQA EHILARYVVLSFSFIGGASIGCTVGVVTGLILGLANIGNLYQMSLLAFSGLLGGLLKE GKKAGAAIGLIVGSLLISLYGEGSAGLMTTLYESLIAVCLFLLTPQSITRKVARYIPG TVEHLQEQQQYARKIRDVTAQKVDQFSNVFHALSESFATFYQASDEQTDDSEVDLFLS KITEHSCQTCYKKNRCWVQNFDKTYDLMKQVMLETEEKEYASNRRLKKEFQQYCSKSK QVEELIEDELAHHHAHLTLKKKVQDSRRLVAEQLLGVSEVMADFSREIKREREQHFLQ EEQIIEALQHFGIEIQHVEIYSLEQGNIDIEMTIPFSGHGESEKIIAPMLSDILEEQI LVKAEQHSPHPNGYSHVAFGSTKSYRVSTGAAHAAKGGGLVSGDSYSMMELGARKYAA AISDGMGNGARAHFESNETIKLLEKILESGIDEKIAIKTINSILSLRTTDEIYSTLDL SIIDLQDASCKFLKVGSTPSFIKRGDQVMKVQASNLPIGIINEFDVEVVSEQLKAGDL LIMMSDGIFEGPKHVENHDLWMKRKMKGLKTNDPQEIADLLMEEVIRTRSGQIEDDMT VVVVRIDHNTPKWASIPVPAIFQNKQEIS*" gene 70538..73021 /gene="spoIIE" /locus_tag="BSU_00640" /old_locus_tag="BSU00640" downshifts 70579 /Source="Nicolas_upshifts" /id="D31" /incds=0 /nref=1 /ntot=20 /MaxReadThrough="5.5737" /MaxDrop="3.93473" /score="25.2769629" /energy="-10.8" /TU="U60,U61" /idTUdmin="U58" /TUdmin=44 /isTUend="FALSE" S_feature complement(71190..71799) /Source="Nicolas_S_feature" /locus_tag="new_71190_71799_c" /HighExp="S8, S6, S4, S5, S3, S7, M9-stat, T5.0H, LoTm, Pyr" /AntisenseName="spoIIE" /AntisenseCor="0.685558251745638" /AntisenseRegPval="-38" /CDS_PredictionProba="NA" /TUshortSig="SigEF" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S37" downshifts complement(71216) /Source="Nicolas_upshifts" /id="D32" /incds=1 /nref=2 /ntot=11 /MaxReadThrough="2.2425" /MaxDrop="4.29972" /score="-0.425236437" /energy="-13.9" /TU="NA" /idTUdmin="U62" /TUdmin=11 /isTUend="TRUE" promotor_-10 complement(71772..71790) /Source="Nicolas_upshift_promotors" /id="U62" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1071 /SigmaFactorBS="cttttttcagccttcggtttgatgcatattctttttcctctg tttcaAGCATAacttgtttcattaagTCATATGTTTTATCAAAGTtctgtacccagca c" /listShort="S37" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(71798) /Source="Nicolas_upshifts" /id="U62" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1071 /SigmaFactorBS="cttttttcagccttcggtttgatgcatattctttttcctctg tttcaAGCATAacttgtttcattaagTCATATGTTTTATCAAAGTtctgtacccagca c" /listShort="S37" /GFF_Attribute="listLong" promotor_-35 complement(71806..71811) /Source="Nicolas_upshift_promotors" /id="U62" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1071 /SigmaFactorBS="cttttttcagccttcggtttgatgcatattctttttcctctg tttcaAGCATAacttgtttcattaagTCATATGTTTTATCAAAGTtctgtacccagca c" /listShort="S37" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 72003..72009 /Source="Nicolas_upshift_promotors" /id="U63" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=158 /SigmaFactorBS="ccttgttgctgaacagcttttaggcgtttctgAGGTTATggc cgacttttctcGGGAAATAAAAAGAGAGCGagaacaacactttctgcaggaagagcaa a" /listShort="yabS" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 72024..72042 /Source="Nicolas_upshift_promotors" /id="U63" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=158 /SigmaFactorBS="ccttgttgctgaacagcttttaggcgtttctgAGGTTATggc cgacttttctcGGGAAATAAAAAGAGAGCGagaacaacactttctgcaggaagagcaa a" /listShort="yabS" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 72031 /Source="Nicolas_upshifts" /id="U63" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=158 /SigmaFactorBS="ccttgttgctgaacagcttttaggcgtttctgAGGTTATggc cgacttttctcGGGAAATAAAAAGAGAGCGagaacaacactttctgcaggaagagcaa a" /listShort="yabS" /GFF_Attribute="listLong" promotor_-35 73041..73044 /Source="Nicolas_upshift_promotors" /id="U64" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.842157842157842" /psig="0.842157842157842" /xcortree=1198 /SigmaFactorBS="aacaagaaatttcataacgcttccgtataaatcaaaTTTCtt ctggcgaagatgggaATATATGAATCTGAGAATcctcgtattctccaggaggaatgaa t" /listShort="yabS, yabT, tilS, hprT, S38, ftsH" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 73062..73079 /Source="Nicolas_upshift_promotors" /id="U64" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.842157842157842" /psig="0.842157842157842" /xcortree=1198 /SigmaFactorBS="aacaagaaatttcataacgcttccgtataaatcaaaTTTCtt ctggcgaagatgggaATATATGAATCTGAGAATcctcgtattctccaggaggaatgaa t" /listShort="yabS, yabT, tilS, hprT, S38, ftsH" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 73065 /Source="Nicolas_upshifts" /id="U64" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.842157842157842" /psig="0.842157842157842" /xcortree=1198 /SigmaFactorBS="aacaagaaatttcataacgcttccgtataaatcaaaTTTCtt ctggcgaagatgggaATATATGAATCTGAGAATcctcgtattctccaggaggaatgaa t" /listShort="yabS, yabT, tilS, hprT, S38, ftsH" /GFF_Attribute="listLong" CDS 73106..73843 /gene="yabS" /locus_tag="BSU_00650" /old_locus_tag="BSU00650" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_387946.1" /db_xref="EnsemblGenomes-Gn:BSU00650" /db_xref="EnsemblGenomes-Tr:CAB11841" /db_xref="InterPro:IPR002035" /db_xref="InterPro:IPR036465" /db_xref="SubtiList:BG10128" /db_xref="UniProtKB/Swiss-Prot:P37561" /translation="MNNGHLNQILLITDGCSNHGEDPLAMAAFAKEQGITVNVIGIME ENQIDPEAMKEVEGIALAGGGVHQVVYASQLSQTVQMVTKKAMTQTLQGVVNQELKQI LGKNVEMEELSPEKRGEVMEVVDELGETVHLQVLVLVDTSASMAPKLPTVKEALIDLS VSLNSRIGNNEFAMCIFPGKKQEVELVLNWTPKLQSLSTLFAKLSTGGITPTGPAIRE ATLQFEKIRSRRGMLADDERRFDEFGM*" gene 73106..73843 /gene="yabS" /locus_tag="BSU_00650" /old_locus_tag="BSU00650" CDS 73809..74825 /gene="prkT" /locus_tag="BSU_00660" /old_locus_tag="BSU00660" /EC_number="2.7.11.1" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:23634894, 24731262, 25278935" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 23634894, 24731262, 25278935; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="serine/threonine-protein kinase" /protein_id="NP_387947.2" /db_xref="EnsemblGenomes-Gn:BSU00660" /db_xref="EnsemblGenomes-Tr:CAB11842" /db_xref="GOA:P37562" /db_xref="InterPro:IPR000719" /db_xref="InterPro:IPR011009" /db_xref="InterPro:IPR017441" /db_xref="SubtiList:BG10129" /db_xref="UniProtKB/Swiss-Prot:P37562" /translation="MMNDALTSLACSLKPGTTIKGKWNGNTYTLRKQLGKGANGIVYL AETSDGHVALKVSDDSLSITSEVNVLKSFSKAQSVTMGPSFFDTDDAYIPSANTKVSF YAMEYIKGPLLLKYVSDKGAEWIPVLMIQLLSSLSVLHQQGWIFGDLKPDNLIVTGPP ARIRCIDVGGTTKEGRAIKEYTEFYDRGYWGYGTRKAEPSYDLFAVAMIMINSVHKKE FKKTNQPKEQLRSLIEGNPLLQKYKKALFSALNGDYQSADEMKKDMLDAGQKAAQRKQ PIKASPQPATRQRQQKPRQGKITKTRYTPKQKPAKSGGLFETTLIVISVLALYFAYII FFLI*" gene 73809..74825 /gene="prkT" /locus_tag="BSU_00660" /old_locus_tag="BSU00660" promotor_-35 74357..74363 /Source="Nicolas_upshift_promotors" /id="U65" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=159 /SigmaFactorBS="aaggaaggccgggcgataaaagagtatacggaGTTTTATgac agaggctattggGGGTATGGAACAAGAAAGGcagagccatcctatgatctgttcgcag t" /GFF_Attribute="listShort" /listLong="tilS, hprT, S38, ftsH" /label="promotor_-35" promotor_-10 74379..74397 /Source="Nicolas_upshift_promotors" /id="U65" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=159 /SigmaFactorBS="aaggaaggccgggcgataaaagagtatacggaGTTTTATgac agaggctattggGGGTATGGAACAAGAAAGGcagagccatcctatgatctgttcgcag t" /GFF_Attribute="listShort" /listLong="tilS, hprT, S38, ftsH" /label="promotor_-10" upshifts 74385 /Source="Nicolas_upshifts" /id="U65" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=159 /SigmaFactorBS="aaggaaggccgggcgataaaagagtatacggaGTTTTATgac agaggctattggGGGTATGGAACAAGAAAGGcagagccatcctatgatctgttcgcag t" /GFF_Attribute="listShort" /listLong="tilS, hprT, S38, ftsH" promotor_-35 74855..74862 /Source="Nicolas_upshift_promotors" /id="U66" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.723276723276723" /psig=1 /xcortree=1948 /SigmaFactorBS="atggtgcaaactgcagagcctatgcttctTCTTTGCTtggag gggttgaaAGTGTTAGGATATGAATATCtttaaaatacctgctcattgtgaggaggac a" /listShort="tilS, hprT, S38, ftsH, S39, S40, coaX, hslO, yacD" /listLong="cysK, pabB, pabA, pabC, sul, folB, folK, yazB, dusB, S42, lysS, S43, rrnJ-16S" /label="promotor_-35" promotor_-10 74876..74895 /Source="Nicolas_upshift_promotors" /id="U66" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.723276723276723" /psig=1 /xcortree=1948 /SigmaFactorBS="atggtgcaaactgcagagcctatgcttctTCTTTGCTtggag gggttgaaAGTGTTAGGATATGAATATCtttaaaatacctgctcattgtgaggaggac a" /listShort="tilS, hprT, S38, ftsH, S39, S40, coaX, hslO, yacD" /listLong="cysK, pabB, pabA, pabC, sul, folB, folK, yazB, dusB, S42, lysS, S43, rrnJ-16S" /label="promotor_-10" upshifts 74886 /Source="Nicolas_upshifts" /id="U66" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.723276723276723" /psig=1 /xcortree=1948 /SigmaFactorBS="atggtgcaaactgcagagcctatgcttctTCTTTGCTtggag gggttgaaAGTGTTAGGATATGAATATCtttaaaatacctgctcattgtgaggaggac a" /listShort="tilS, hprT, S38, ftsH, S39, S40, coaX, hslO, yacD" /listLong="cysK, pabB, pabA, pabC, sul, folB, folK, yazB, dusB, S42, lysS, S43, rrnJ-16S" CDS 74929..76347 /gene="tilS" /locus_tag="BSU_00670" /old_locus_tag="BSU00670" /EC_number="6.3.4.19" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:12682299, 14527414, 16039592, 17005971, 22720735, 24001521" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12682299, 14527414, 16039592, 17005971, 22720735, 24001521; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="tRNA(ile2) lysidine synthetase" /protein_id="NP_387948.1" /db_xref="EnsemblGenomes-Gn:BSU00670" /db_xref="EnsemblGenomes-Tr:CAB11843" /db_xref="GOA:P37563" /db_xref="InterPro:IPR011063" /db_xref="InterPro:IPR012094" /db_xref="InterPro:IPR012795" /db_xref="InterPro:IPR012796" /db_xref="InterPro:IPR014729" /db_xref="InterPro:IPR015262" /db_xref="InterPro:IPR020825" /db_xref="SubtiList:BG10130" /db_xref="UniProtKB/Swiss-Prot:P37563" /translation="MKSVKDFLNKHNLTLKGATIIVGVSGGPDSMALLHALHTLCGRS ANVIAAHVDHRFRGAESEEDMRFVQAYCKAEQLVCETAQINVTAYAQEKGLNKQAAAR DCRYQFFEEIMSKHQADYLALAHHGDDQVETMLMKLAKGTLGTGLAGMQPVRRFGTGR IIRPFLTITKEEILHYCHENGLSYRTDESNAKDDYTRNRFRKTVLPFLKQESPDVHKR FQKVSEALTEDEQFLQSLTKDEMNKVITSQSNTSVEINSSQLLALPMPLQRRGVQLIL NYLYENVPSSFSAHHIQQFLDWAENGGPSGVLDFPKGLKVVKSYQTCLFTFEQWQCKN VPFEYQISGAADETAVLPNGYLIEARHYADSPEEHGNAVFITSEKKVRFPLTIRTRKA GDRIKLKGMNGSKKVKDIFIDKKLPLQERDNWPIVTDASGEIIWIPGLKKSIFEDLVI PNSDRIVLQYRQHEKCRGQAKS*" gene 74929..76347 /gene="tilS" /locus_tag="BSU_00670" /old_locus_tag="BSU00670" promotor_-35 75724..75731 /Source="Nicolas_upshift_promotors" /id="U67" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.721278721278721" /psig="0.999000999001" /xcortree=1885 /SigmaFactorBS="aaatcaattcctctcaattgcttgccctcccgatgCCTTTAC AaagaagaggagttcAACTAATATTAAACTATCTTtatgaaaacgttccatcatcctt t" /listShort="hprT, S38, ftsH, S39, S40, coaX, hslO, yacD" /listLong="cysK, pabB, pabA, pabC, sul, folB, folK, yazB, dusB, S42, lysS, S43, rrnJ-16S" /label="promotor_-35" promotor_-10 75746..75765 /Source="Nicolas_upshift_promotors" /id="U67" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.721278721278721" /psig="0.999000999001" /xcortree=1885 /SigmaFactorBS="aaatcaattcctctcaattgcttgccctcccgatgCCTTTAC AaagaagaggagttcAACTAATATTAAACTATCTTtatgaaaacgttccatcatcctt t" /listShort="hprT, S38, ftsH, S39, S40, coaX, hslO, yacD" /listLong="cysK, pabB, pabA, pabC, sul, folB, folK, yazB, dusB, S42, lysS, S43, rrnJ-16S" /label="promotor_-10" upshifts 75749 /Source="Nicolas_upshifts" /id="U67" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.721278721278721" /psig="0.999000999001" /xcortree=1885 /SigmaFactorBS="aaatcaattcctctcaattgcttgccctcccgatgCCTTTAC AaagaagaggagttcAACTAATATTAAACTATCTTtatgaaaacgttccatcatcctt t" /listShort="hprT, S38, ftsH, S39, S40, coaX, hslO, yacD" /listLong="cysK, pabB, pabA, pabC, sul, folB, folK, yazB, dusB, S42, lysS, S43, rrnJ-16S" downshifts complement(76342) /Source="Nicolas_upshifts" /id="D33" /incds=0 /nref=2 /ntot=142 /MaxReadThrough="2.51342" /MaxDrop="2.96272" /score="12.3455896" /energy="-9.1" /TU="NA" /idTUdmin="U68" /TUdmin="-11" /isTUend="TRUE" CDS 76344..76886 /gene="hprT" /locus_tag="BSU_00680" /old_locus_tag="BSU00680" /EC_number="2.4.2.8" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:3110131, 6408059, 24001521" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 3110131, 6408059, 24001521; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="hypoxanthine-guanine phosphoribosyltransferase" /protein_id="NP_387949.1" /db_xref="EnsemblGenomes-Gn:BSU00680" /db_xref="EnsemblGenomes-Tr:CAB11844" /db_xref="GOA:P37472" /db_xref="InterPro:IPR000836" /db_xref="InterPro:IPR005904" /db_xref="InterPro:IPR029057" /db_xref="SubtiList:BG10131" /db_xref="UniProtKB/Swiss-Prot:P37472" /translation="MMKHDIEKVLISEEEIQKKVKELGAELTSEYQDTFPLAIGVLKG ALPFMADLIKHIDTYLEMDFMDVSSYGNSTVSSGEVKIIKDLDTSVEGRDILIIEDII DSGLTLSYLVELFRYRKAKSIKIVTLLDKPSGRKADIKADFVGFEVPDAFVVGYGLDY AERYRNLPYIGVLKPAVYES*" gene 76344..76886 /gene="hprT" /locus_tag="BSU_00680" /old_locus_tag="BSU00680" upshifts complement(76749) /Source="Nicolas_upshifts" /id="U68" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.988011988011988" /psig="0.002997002997003" /xcortree=41 /SigmaFactorBS="aacccactacaaacgcgtcaggaacttcaaaacCGACaaagt ctgctttgatgtCCGCTtttcttccgctcggtttatccaaaagggtaacaatcttaat t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 complement(76751..76755) /Source="Nicolas_upshift_promotors" /id="U68" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.988011988011988" /psig="0.002997002997003" /xcortree=41 /SigmaFactorBS="aacccactacaaacgcgtcaggaacttcaaaacCGACaaagt ctgctttgatgtCCGCTtttcttccgctcggtttatccaaaagggtaacaatcttaat t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 complement(76773..76776) /Source="Nicolas_upshift_promotors" /id="U68" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.988011988011988" /psig="0.002997002997003" /xcortree=41 /SigmaFactorBS="aacccactacaaacgcgtcaggaacttcaaaacCGACaaagt ctgctttgatgtCCGCTtttcttccgctcggtttatccaaaagggtaacaatcttaat t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" S_feature 76887..76983 /Source="Nicolas_S_feature" /locus_tag="new_76887_76983" /HighExp="Diami, H2O2, dia5, G135, dia15, G150, Paraq, C90, G180, Salt" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA, SigEF" /TUshortPSig="0.999, 1, 0.842" /TUlongSig="SigB, SigA" /TUlongPSig="1, 0.99" /label="S38" CDS 76984..78897 /gene="ftsH" /locus_tag="BSU_00690" /old_locus_tag="BSU00690" /EC_number="3.4.24.-" /function="16.9: Replicate" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:9076729, 9084181, 9287010, 9352926, 10851010, 10913836, 12533473, 24001521, 22720735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9076729, 9084181, 9287010, 9352926, 10851010, 10913836, 12533473, 24001521, 22720735; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="ATP-dependent cytoplasmic membrane protease" /protein_id="NP_387950.1" /db_xref="EnsemblGenomes-Gn:BSU00690" /db_xref="EnsemblGenomes-Tr:CAB11845" /db_xref="GOA:P37476" /db_xref="InterPro:IPR000642" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR003959" /db_xref="InterPro:IPR003960" /db_xref="InterPro:IPR005936" /db_xref="InterPro:IPR011546" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR037219" /db_xref="SubtiList:BG10132" /db_xref="UniProtKB/Swiss-Prot:P37476" /translation="MNRVFRNTIFYLLILLVVIGVVSYFQTSNPKTENMSYSTFIKNL DDGKVDSVSVQPVRGVYEVKGQLKNYDKDQYFLTHVPEGKGADQIFNALKKTDVKVEP AQETSGWVTFLTTIIPFVIIFILFFFLLNQAQGGGSRVMNFGKSKAKLYTEEKKRVKF KDVAGADEEKQELVEVVEFLKDPRKFAELGARIPKGVLLVGPPGTGKTLLAKACAGEA GVPFFSISGSDFVEMFVGVGASRVRDLFENAKKNAPCLIFIDEIDAVGRQRGAGLGGG HDEREQTLNQLLVEMDGFSANEGIIIIAATNRADILDPALLRPGRFDRQITVDRPDVI GREAVLKVHARNKPLDETVNLKSIAMRTPGFSGADLENLLNEAALVAARQNKKKIDAR DIDEATDRVIAGPAKKSRVISKKERNIVAYHEGGHTVIGLVLDEADMVHKVTIVPRGQ AGGYAVMLPREDRYFQTKPELLDKIVGLLGGRVAEEIIFGEVSTGAHNDFQRATNIAR RMVTEFGMSEKLGPLQFGQSQGGQVFLGRDFNNEQNYSDQIAYEIDQEIQRIIKECYE RAKQILTENRDKLELIAQTLLKVETLDAEQIKHLIDHGTLPERNFSDDEKNDDVKVNI LTKTEEKKDDTKE*" gene 76984..78897 /gene="ftsH" /locus_tag="BSU_00690" /old_locus_tag="BSU00690" downshifts 78895 /Source="Nicolas_upshifts" /id="D34" /incds=0 /nref=187 /ntot=269 /MaxReadThrough="5.00908" /MaxDrop="8.91482" /score="38.4132386" /energy="-12.9" /TU="U66,U67" /idTUdmin="U64" /TUdmin=0 /isTUend="TRUE" misc_feature complement(78934..78938) /Source="Nicolas_upshift_promotors" /id="U69" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.955044955044955" /psig="0.000999000999001" /xcortree=66 /SigmaFactorBS="aaatcgataccagaattggatgattgtaaaagccgcagctga gccaatcatttacataaaaaaaCTGCCagcgtcagccggcagtttttttagaaagaaa g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" S_feature 78940..79025 /Source="Nicolas_S_feature" /locus_tag="new_78940_79025" /HighExp="H2O2, G180, G135, dia15, Paraq, G150, Oxctl, Diami, Cold, LBGexp" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="0.999, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S39" upshifts complement(78942) /Source="Nicolas_upshifts" /id="U69" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.955044955044955" /psig="0.000999000999001" /xcortree=66 /SigmaFactorBS="aaatcgataccagaattggatgattgtaaaagccgcagctga gccaatcatttacataaaaaaaCTGCCagcgtcagccggcagtttttttagaaagaaa g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 79002..79009 /Source="Nicolas_upshift_promotors" /id="U70" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.531468531468531" /psig=1 /xcortree=1864 /SigmaFactorBS="gcggcttttacaatcatccaattctggtatcgattTGTTTAC AaatgagccgctgaTCGTGTATGGTATTGTAGAAtgtttgtaaaaagtaaagtagaga a" /listShort="S40, coaX, hslO, yacD, cysK" /listLong="pabB, pabA, pabC, sul, folB, folK, yazB, dusB, S42, lysS, S43, rrnJ-16S" /label="promotor_-35" promotor_-10 79023..79042 /Source="Nicolas_upshift_promotors" /id="U70" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.531468531468531" /psig=1 /xcortree=1864 /SigmaFactorBS="gcggcttttacaatcatccaattctggtatcgattTGTTTAC AaatgagccgctgaTCGTGTATGGTATTGTAGAAtgtttgtaaaaagtaaagtagaga a" /listShort="S40, coaX, hslO, yacD, cysK" /listLong="pabB, pabA, pabC, sul, folB, folK, yazB, dusB, S42, lysS, S43, rrnJ-16S" /label="promotor_-10" S_feature 79027..79091 /Source="Nicolas_S_feature" /locus_tag="new_79027_79091" /HighExp="dia5, H2O2, dia15, Paraq, Diami, G180, LBGexp, Oxctl, G135, G150" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA, SigA" /TUshortPSig="1, 0.999, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S40" upshifts 79027 /Source="Nicolas_upshifts" /id="U70" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.531468531468531" /psig=1 /xcortree=1864 /SigmaFactorBS="gcggcttttacaatcatccaattctggtatcgattTGTTTAC AaatgagccgctgaTCGTGTATGGTATTGTAGAAtgtttgtaaaaagtaaagtagaga a" /listShort="S40, coaX, hslO, yacD, cysK" /listLong="pabB, pabA, pabC, sul, folB, folK, yazB, dusB, S42, lysS, S43, rrnJ-16S" CDS 79092..79868 /gene="coaX" /locus_tag="BSU_00700" /old_locus_tag="BSU00700" /EC_number="2.7.1.33" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:15795230, 16905099, 24784177" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15795230, 16905099, 24784177; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="pantothenate kinase type III" /protein_id="NP_387951.2" /db_xref="EnsemblGenomes-Gn:BSU00700" /db_xref="EnsemblGenomes-Tr:CAB11846" /db_xref="GOA:P37564" /db_xref="InterPro:IPR004619" /db_xref="SubtiList:BG10133" /db_xref="UniProtKB/Swiss-Prot:P37564" /translation="MLLVIDVGNTNTVLGVYHDGKLEYHWRIETSRHKTEDEFGMILR SLFDHSGLMFEQIDGIIISSVVPPIMFALERMCTKYFHIEPQIVGPGMKTGLNIKYDN PKEVGADRIVNAVAAIHLYGNPLIVVDFGTATTYCYIDENKQYMGGAIAPGITISTEA LYSRAAKLPRIEITRPDNIIGKNTVSAMQSGILFGYVGQVEGIVKRMKWQAKQEPKVI ATGGLAPLIANESDCIDIVDPFLTLKGLELIYERNRVGSV*" gene 79092..79868 /gene="coaX" /locus_tag="BSU_00700" /old_locus_tag="BSU00700" CDS 79880..80755 /gene="hslO" /locus_tag="BSU_00710" /old_locus_tag="BSU00710" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 11323724, 15023991; Product type f: factor" /codon_start=1 /transl_table=11 /product="disulfide bond chaperone (heat shock protein HSP33)" /protein_id="NP_387952.1" /db_xref="EnsemblGenomes-Gn:BSU00710" /db_xref="EnsemblGenomes-Tr:CAB11847" /db_xref="GOA:P37565" /db_xref="InterPro:IPR000397" /db_xref="InterPro:IPR016153" /db_xref="InterPro:IPR016154" /db_xref="PDB:1VZY" /db_xref="SubtiList:BG10134" /db_xref="UniProtKB/Swiss-Prot:P37565" /translation="MDYLVKALAYDGKVRAYAARTTDMVNEGQRRHGTWPTASAALGR TMTASLMLGAMLKGDDKLTVKIEGGGPIGAIVADANAKGEVRAYVSNPQVHFDLNEQG KLDVRRAVGTNGTLSVVKDLGLREFFTGQVEIVSGELGDDFTYYLVSSEQVPSSVGVG VLVNPDNTILAAGGFIIQLMPGTDDETITKIEQRLSQVEPISKLIQKGLTPEEILEEV LGEKPEILETMPVRFHCPCSKERFETAILGLGKKEIQDMIEEDGQAEAVCHFCNEKYL FTKEELEGLRDQTTR*" gene 79880..80755 /gene="hslO" /locus_tag="BSU_00710" /old_locus_tag="BSU00710" CDS 80802..81695 /gene="yacD" /locus_tag="BSU_00720" /old_locus_tag="BSU00720" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15187182, 15856219; Product type f: factor" /codon_start=1 /transl_table=11 /product="putative protein chaperone accessory lipoproteinfactor" /protein_id="NP_387953.1" /db_xref="EnsemblGenomes-Gn:BSU00720" /db_xref="EnsemblGenomes-Tr:CAB11848" /db_xref="GOA:P37566" /db_xref="InterPro:IPR000297" /db_xref="InterPro:IPR023058" /db_xref="InterPro:IPR027304" /db_xref="SubtiList:BG10135" /db_xref="UniProtKB/Swiss-Prot:P37566" /translation="MKSRTIWTIILGALLVCCIAVAYTLTKSQAGASSSGESIATIGG KSVTREEWLKEMEDQYGKSTLEDMINVRVVEQLAKKNKLKISKSEVDREFLLIKAVNN SFYEDEHTTEKEWKDQIRYNILLEDLLTRDIDISNKELESFYNKNKELYQFDDSYRIR HIVVKDEEEAREVLKELKGGSSFEAVAAERSTDRYTSPYGGDLGFVTEASDNIPSAYI EEAKTLKEDEWSQEPIKVSNGYAIIQLKEKLKARTFSFDEVKDQIRRQIAMDQLGDKA TVKTLWKEADVSWFYGEKSTK*" gene 80802..81695 /gene="yacD" /locus_tag="BSU_00720" /old_locus_tag="BSU00720" promotor_-35 81425..81430 /Source="Nicolas_upshift_promotors" /id="U71" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.995004995004995" /psig="0.995004995004995" /xcortree=1220 /SigmaFactorBS="catcaccatacggcggagatttaggttttgtcacagaGGCAT CagacaacattccatcaGCATACATTGAAGAGGCGAaaacactcaaagaggatgaatg g" /listShort="cysK" /listLong="pabB, pabA, pabC, sul, folB, folK, yazB, dusB, S42, lysS" /label="promotor_-35" promotor_-10 81447..81465 /Source="Nicolas_upshift_promotors" /id="U71" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.995004995004995" /psig="0.995004995004995" /xcortree=1220 /SigmaFactorBS="catcaccatacggcggagatttaggttttgtcacagaGGCAT CagacaacattccatcaGCATACATTGAAGAGGCGAaaacactcaaagaggatgaatg g" /listShort="cysK" /listLong="pabB, pabA, pabC, sul, folB, folK, yazB, dusB, S42, lysS" /label="promotor_-10" upshifts 81448 /Source="Nicolas_upshifts" /id="U71" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.995004995004995" /psig="0.995004995004995" /xcortree=1220 /SigmaFactorBS="catcaccatacggcggagatttaggttttgtcacagaGGCAT CagacaacattccatcaGCATACATTGAAGAGGCGAaaacactcaaagaggatgaatg g" /listShort="cysK" /listLong="pabB, pabA, pabC, sul, folB, folK, yazB, dusB, S42, lysS" promotor_-35 81694..81701 /Source="Nicolas_upshift_promotors" /id="U72" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.844155844155844" /psig=1 /xcortree=1740 /SigmaFactorBS="tcttggttttatggggaaaaaagtactaagtGATTGACAaaa aattttgaaatTGATAGATTATATACATAATaccaatacaaatagtcggaaattgagg t" /listShort="cysK, pabB, pabA, pabC, sul" /listLong="folB, folK, yazB, dusB, S42, lysS, S43, rrnJ-16S" /label="promotor_-35" promotor_-10 81716..81735 /Source="Nicolas_upshift_promotors" /id="U72" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.844155844155844" /psig=1 /xcortree=1740 /SigmaFactorBS="tcttggttttatggggaaaaaagtactaagtGATTGACAaaa aattttgaaatTGATAGATTATATACATAATaccaatacaaatagtcggaaattgagg t" /listShort="cysK, pabB, pabA, pabC, sul" /listLong="folB, folK, yazB, dusB, S42, lysS, S43, rrnJ-16S" /label="promotor_-10" upshifts 81723 /Source="Nicolas_upshifts" /id="U72" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.844155844155844" /psig=1 /xcortree=1740 /SigmaFactorBS="tcttggttttatggggaaaaaagtactaagtGATTGACAaaa aattttgaaatTGATAGATTATATACATAATaccaatacaaatagtcggaaattgagg t" /listShort="cysK, pabB, pabA, pabC, sul" /listLong="folB, folK, yazB, dusB, S42, lysS, S43, rrnJ-16S" CDS 81771..82697 /gene="cysK" /locus_tag="BSU_00730" /old_locus_tag="BSU00730" /EC_number="2.5.1.47" /EC_number="4.4.1.1" /function="16.3: Control" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:11390694, 15760717, 16267287, 16513748, 17056751, 18974048" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11390694, 15760717, 16267287, 16513748, 17056751, 18974048; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="cysteine synthase" /protein_id="NP_387954.1" /db_xref="EnsemblGenomes-Gn:BSU00730" /db_xref="EnsemblGenomes-Tr:CAB11849" /db_xref="GOA:P37887" /db_xref="InterPro:IPR001216" /db_xref="InterPro:IPR001926" /db_xref="InterPro:IPR005856" /db_xref="InterPro:IPR005859" /db_xref="InterPro:IPR036052" /db_xref="SubtiList:BG10136" /db_xref="UniProtKB/Swiss-Prot:P37887" /translation="MVRVANSITELIGNTPIVKLNRLADENSADVYLKLEYMNPGSSV KDRIGLAMIEAAEKEGKLKAGNTIIEPTSGNTGIGLAMVAAAKGLKAILVMPDTMSME RRNLLRAYGAELVLTPGAEGMKGAIKKAEELAEKHGYFVPQQFNNPSNPEIHRQTTGK EIVEQFGDDQLDAFVAGIGTGGTITGAGEVLKEAYPSIKIYAVEPSDSPVLSGGKPGP HKIQGIGAGFVPDILNTEVYDEIFPVKNEEAFEYARRAAREEGILGGISSGAAIYAAL QVAKKLGKGKKVLAIIPSNGERYLSTPLYQFD*" gene 81771..82697 /gene="cysK" /locus_tag="BSU_00730" /old_locus_tag="BSU00730" downshifts 82690 /Source="Nicolas_upshifts" /id="D35" /incds=0 /nref=156 /ntot=259 /MaxReadThrough="5.90023" /MaxDrop="5.38596" /score="41.7897705" /energy="-11.4" /TU="U72" /idTUdmin="U70" /TUdmin=10 /isTUend="TRUE" promotor_-35 82744..82752 /Source="Nicolas_upshift_promotors" /id="U73" /multdbtbs="-" /comp="M2" /sig="SigI" /pcomp="0.787212787212787" /psig="0.787212787212787" /xcortree=1723 /SigmaFactorBS="aactcccggttcgccgggagtttttttatatttcgtGCATCA AATatgccatgtctgcGACGAATGTtattcttggaagagaaattcacttttttcacta a" /listShort="pabB" /listLong="pabA, pabC, sul, folB, folK, yazB, dusB, S42, lysS" /label="promotor_-35" promotor_-10 82766..82774 /Source="Nicolas_upshift_promotors" /id="U73" /multdbtbs="-" /comp="M2" /sig="SigI" /pcomp="0.787212787212787" /psig="0.787212787212787" /xcortree=1723 /SigmaFactorBS="aactcccggttcgccgggagtttttttatatttcgtGCATCA AATatgccatgtctgcGACGAATGTtattcttggaagagaaattcacttttttcacta a" /listShort="pabB" /listLong="pabA, pabC, sul, folB, folK, yazB, dusB, S42, lysS" /label="promotor_-10" upshifts 82768 /Source="Nicolas_upshifts" /id="U73" /multdbtbs="-" /comp="M2" /sig="SigI" /pcomp="0.787212787212787" /psig="0.787212787212787" /xcortree=1723 /SigmaFactorBS="aactcccggttcgccgggagtttttttatatttcgtGCATCA AATatgccatgtctgcGACGAATGTtattcttggaagagaaattcacttttttcacta a" /listShort="pabB" /listLong="pabA, pabC, sul, folB, folK, yazB, dusB, S42, lysS" promotor_-35 82796..82799 /Source="Nicolas_upshift_promotors" /id="U74" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.7992007992008" /psig="0.998001998001998" /xcortree=2267 /SigmaFactorBS="gcgacgaatgttattcttggaagagaaattcaCTTTtttcac taacaacaTTGCTTTACAATTAAAAACAagtaaaaaagaaaatagaggaatgatacaa a" /listShort="pabB, pabA, pabC, sul, folB, folK, yazB, dusB, S42, lysS" /listLong="S43, rrnJ-16S" /label="promotor_-35" promotor_-10 82814..82833 /Source="Nicolas_upshift_promotors" /id="U74" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.7992007992008" /psig="0.998001998001998" /xcortree=2267 /SigmaFactorBS="gcgacgaatgttattcttggaagagaaattcaCTTTtttcac taacaacaTTGCTTTACAATTAAAAACAagtaaaaaagaaaatagaggaatgatacaa a" /listShort="pabB, pabA, pabC, sul, folB, folK, yazB, dusB, S42, lysS" /listLong="S43, rrnJ-16S" /label="promotor_-10" upshifts 82824 /Source="Nicolas_upshifts" /id="U74" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.7992007992008" /psig="0.998001998001998" /xcortree=2267 /SigmaFactorBS="gcgacgaatgttattcttggaagagaaattcaCTTTtttcac taacaacaTTGCTTTACAATTAAAAACAagtaaaaaagaaaatagaggaatgatacaa a" /listShort="pabB, pabA, pabC, sul, folB, folK, yazB, dusB, S42, lysS" /listLong="S43, rrnJ-16S" CDS 82864..84276 /gene="pabB" /locus_tag="BSU_00740" /old_locus_tag="BSU00740" /EC_number="2.6.1.85" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 2123867, 9084182, 16605270, 17114263, 25288929; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="4-amino-4-deoxychorismate synthase (para-aminobenzoate synthase)" /protein_id="NP_387955.1" /db_xref="EnsemblGenomes-Gn:BSU00740" /db_xref="EnsemblGenomes-Tr:CAB11850" /db_xref="GOA:P28820" /db_xref="InterPro:IPR005801" /db_xref="InterPro:IPR006805" /db_xref="InterPro:IPR015890" /db_xref="InterPro:IPR019999" /db_xref="SubtiList:BG10137" /db_xref="UniProtKB/Swiss-Prot:P28820" /translation="MAQRRPAGKKIPFQKDSFLQQFEKLAQSRKHHVLLESARGGRYS IAGLDPIATVKGKDGITTIKHGDEMLFKEGDPLRAFHSWFKTLETETNHEFPDFQGGA IGFLSYDYARYIENFKMLSLDDLETPDIYFLVFDDIAVYDHQEESLWLITHVNGSDQE TADVKLSELEQMWLTELPAVTSREMKPETAGSFAAPFTEDGFSQAVEKIKQYIASGDV FQVNLSIRQSQSLSVHPYQIYKTLREVNPSPYMAYLETPDFQIICGSPELLVSKKGKL LETRPIAGTRSRGKTNEEDEALANELIHNEKERAEHVMLVDLERNDLGRVSRYGSVRV NEFMAIEKYSHVMHIVSNVQGELQDGYDAVDIIHAVFPGGTITGAPKVRTMEIIEELE PTRRGLYTGSIGWFGYNHDLQFNIVIRTIYATGGQAFMQSGAGVVIDSVPKHEYKESF KKAFAMQRALELSEEETKIR*" gene 82864..84276 /gene="pabB" /locus_tag="BSU_00740" /old_locus_tag="BSU00740" promotor_-35 83666..83668 /Source="Nicolas_upshift_promotors" /id="U75" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.416583416583417" /psig="0.621378621378621" /xcortree=608 /SigmaFactorBS="cctgatttccaaatcatttgcggatcgcctgaacTGCttgtc agcaaaaagggcAAGCTATTAGAGACGAGACcgattgcgggcacccgttccagaggga a" /GFF_Attribute="listShort" /listLong="pabA, pabC, sul, folB, folK, yazB, dusB, S42, lysS" /label="promotor_-35" promotor_-10 83686..83704 /Source="Nicolas_upshift_promotors" /id="U75" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.416583416583417" /psig="0.621378621378621" /xcortree=608 /SigmaFactorBS="cctgatttccaaatcatttgcggatcgcctgaacTGCttgtc agcaaaaagggcAAGCTATTAGAGACGAGACcgattgcgggcacccgttccagaggga a" /GFF_Attribute="listShort" /listLong="pabA, pabC, sul, folB, folK, yazB, dusB, S42, lysS" /label="promotor_-10" upshifts 83692 /Source="Nicolas_upshifts" /id="U75" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.416583416583417" /psig="0.621378621378621" /xcortree=608 /SigmaFactorBS="cctgatttccaaatcatttgcggatcgcctgaacTGCttgtc agcaaaaagggcAAGCTATTAGAGACGAGACcgattgcgggcacccgttccagaggga a" /GFF_Attribute="listShort" /listLong="pabA, pabC, sul, folB, folK, yazB, dusB, S42, lysS" promotor_-35 84033..84040 /Source="Nicolas_upshift_promotors" /id="U76" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.57942057942058" /psig="0.998001998001998" /xcortree=2212 /SigmaFactorBS="agtaagaacgatggaaattatagaagaACTTGAGCcgacacg ccgagGGCTTTATACTGGATCTATAggatggtttggatataatcacgatctgcagttt a" /listShort="pabA, pabC, sul, folB, folK, yazB, dusB, S42, lysS" /listLong="S43, rrnJ-16S" /label="promotor_-35" promotor_-10 84053..84072 /Source="Nicolas_upshift_promotors" /id="U76" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.57942057942058" /psig="0.998001998001998" /xcortree=2212 /SigmaFactorBS="agtaagaacgatggaaattatagaagaACTTGAGCcgacacg ccgagGGCTTTATACTGGATCTATAggatggtttggatataatcacgatctgcagttt a" /listShort="pabA, pabC, sul, folB, folK, yazB, dusB, S42, lysS" /listLong="S43, rrnJ-16S" /label="promotor_-10" upshifts 84066 /Source="Nicolas_upshifts" /id="U76" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.57942057942058" /psig="0.998001998001998" /xcortree=2212 /SigmaFactorBS="agtaagaacgatggaaattatagaagaACTTGAGCcgacacg ccgagGGCTTTATACTGGATCTATAggatggtttggatataatcacgatctgcagttt a" /listShort="pabA, pabC, sul, folB, folK, yazB, dusB, S42, lysS" /listLong="S43, rrnJ-16S" CDS 84290..84874 /gene="pabA" /locus_tag="BSU_00750" /old_locus_tag="BSU00750" /EC_number="2.6.1.85" /EC_number="4.1.3.27" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 9098056, 16605270, 17114263, 24847778; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="4-amino-4-deoxychorismate synthase; anthranilatesynthase (subunit II)" /protein_id="NP_387956.1" /db_xref="EnsemblGenomes-Gn:BSU00750" /db_xref="EnsemblGenomes-Tr:CAB11851" /db_xref="GOA:P28819" /db_xref="InterPro:IPR006221" /db_xref="InterPro:IPR017926" /db_xref="InterPro:IPR029062" /db_xref="SubtiList:BG10138" /db_xref="UniProtKB/Swiss-Prot:P28819" /translation="MILMIDNYDSFTYNLVQYLGELGEELVVKRNDSITIDEIEELSP DFLMISPGPCSPDEAGISLEAIKHFAGKIPIFGVCLGHQSIAQVFGGDVVRAERLMHG KTSDIEHDGKTIFEGLKNPLVATRYHSLIVKPETLPSCFTVTAQTKEGEIMAIRHNDL PIEGVQFHPESIMTSFGKEMLRNFIETYRKEVIA*" gene 84290..84874 /gene="pabA" /locus_tag="BSU_00750" /old_locus_tag="BSU00750" CDS 84874..85755 /gene="pabC" /locus_tag="BSU_00760" /old_locus_tag="BSU00760" /EC_number="4.1.3.38" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 10876155, 1644759, 22720735; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="4-amino-4-deoxychorismate pyruvate-lyase" /protein_id="NP_387957.1" /db_xref="EnsemblGenomes-Gn:BSU00760" /db_xref="EnsemblGenomes-Tr:CAB11852" /db_xref="GOA:P28821" /db_xref="InterPro:IPR001544" /db_xref="InterPro:IPR017824" /db_xref="InterPro:IPR018300" /db_xref="InterPro:IPR036038" /db_xref="SubtiList:BG10139" /db_xref="UniProtKB/Swiss-Prot:P28821" /translation="MIYVNGRYMEEKDAVLSPFDHGFLYGIGVFETFRLYEGCPFLLD WHIERLERALKDLQIEYTVSKHEILEMLDKLLKLNDIKDGNARVRLNISAGISDKGFV AQTYDKPTVLCFVNQLKPESLPLQKEGKVLSIRRNTPEGSFRLKSHHYLNNMYAKREI GNDPRVEGIFLTEDGAVAEGIISNVFWRKGRCIYTPSLDTGILDGVTRRFIIENAKDI GLELKTGRYELEALLTADEAWMTNSVLEIIPFTKIEEVNYGSQSGEATSALQLLYKKE IKNMIHEKGGRAWRSTQ*" gene 84874..85755 /gene="pabC" /locus_tag="BSU_00760" /old_locus_tag="BSU00760" CDS 85737..86594 /gene="folP" /locus_tag="BSU_00770" /old_locus_tag="BSU00770" /EC_number="2.5.1.15" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 2123867, 11007651; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="dihydropteroate synthase" /protein_id="NP_387958.1" /db_xref="EnsemblGenomes-Gn:BSU00770" /db_xref="EnsemblGenomes-Tr:CAB11853" /db_xref="GOA:P28822" /db_xref="InterPro:IPR000489" /db_xref="InterPro:IPR006390" /db_xref="InterPro:IPR011005" /db_xref="SubtiList:BG10140" /db_xref="UniProtKB/Swiss-Prot:P28822" /translation="MAQHTIDQTQVIHTKPSALSYKEKTLVMGILNVTPDSFSDGGKY DSLDKALLHAKEMIDDGAHIIDIGGESTRPGAECVSEDEEMSRVIPVIERITKELGVP ISVDTYKASVADEAVKAGASIINDIWGAKHDPKMASVAAEHNVPIVLMHNRPERNYND LLPDMLSDLMESVKIAVEAGVDEKNIILDPGIGFAKTYHDNLAVMNKLEIFSGLGYPV LLATSRKRFIGRVLDLPPEERAEGTGATVCLGIQKGCDIVRVHDVKQIARMAKMMDAM LNKGGVHHG*" gene 85737..86594 /gene="folP" /locus_tag="BSU_00770" /old_locus_tag="BSU00770" CDS 86587..86949 /gene="folB" /locus_tag="BSU_00780" /old_locus_tag="BSU00780" /EC_number="4.1.2.25" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 16188473, 17176045, 17388809; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="dihydroneopterin aldolase" /protein_id="NP_387959.1" /db_xref="EnsemblGenomes-Gn:BSU00780" /db_xref="EnsemblGenomes-Tr:CAB11854" /db_xref="GOA:P28823" /db_xref="InterPro:IPR006156" /db_xref="InterPro:IPR006157" /db_xref="SubtiList:BG10141" /db_xref="UniProtKB/Swiss-Prot:P28823" /translation="MDKVYVEGMEFYGYHGVFTEENKLGQRFKVDLTAELDLSKAGQT DDLEQTINYAELYHVCKDIVEGEPVKLVETLAERIAGTVLGKFQPVQQCTVKVIKPDP PIPGHYKSVAIEITRKKS*" gene 86587..86949 /gene="folB" /locus_tag="BSU_00780" /old_locus_tag="BSU00780" CDS 86946..87449 /gene="folK" /locus_tag="BSU_00790" /old_locus_tag="BSU00790" /EC_number="2.7.6.3" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 17029412; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="7,8-dihydro-6-hydroxymethylpterin pyrophosphokinase" /protein_id="NP_387960.1" /db_xref="EnsemblGenomes-Gn:BSU00790" /db_xref="EnsemblGenomes-Tr:CAB11855" /db_xref="GOA:P29252" /db_xref="InterPro:IPR000550" /db_xref="InterPro:IPR035907" /db_xref="SubtiList:BG10142" /db_xref="UniProtKB/Swiss-Prot:P29252" /translation="MNNIAYIALGSNIGDRETYLRQAVALLHQHAAVTVTKVSSIYET DPVGYEDQAQFLNMAVEIKTSLNPFELLELTQQIENELGRTREVRWGPRTADLDILLF NRENIETEQLIVPHPRMYERLFVLAPLAEICQQVEKEATSAETDQEGVRVWKQKSGVD EFVHSES*" gene 86946..87449 /gene="folK" /locus_tag="BSU_00790" /old_locus_tag="BSU00790" CDS 87401..87610 /gene="yazB" /locus_tag="BSU_00800" /old_locus_tag="BSU00800" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative transcriptional regulator" /protein_id="NP_387961.1" /db_xref="EnsemblGenomes-Gn:BSU00800" /db_xref="EnsemblGenomes-Tr:CAB11856" /db_xref="GOA:O31417" /db_xref="InterPro:IPR001387" /db_xref="InterPro:IPR010982" /db_xref="SubtiList:BG12701" /db_xref="UniProtKB/Swiss-Prot:O31417" /translation="MEAEIWGRRIRAFRKLKGYTQEGFAKALGISVSILGEIERGNRL PSAAIIQDAADVLNISADELAPPEK*" gene 87401..87610 /gene="yazB" /locus_tag="BSU_00800" /old_locus_tag="BSU00800" CDS 87634..88635 /gene="dusB" /locus_tag="BSU_00810" /old_locus_tag="BSU00810" /EC_number="1.-.-.-" /function="16.6: Maintain" /function="16.2: Construct biomass (Anabolism)" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 11983710, 15698474, 26112661; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="tRNA-dihydrouridine synthase B" /protein_id="NP_387962.1" /db_xref="EnsemblGenomes-Gn:BSU00810" /db_xref="EnsemblGenomes-Tr:CAB11857" /db_xref="GOA:P37567" /db_xref="InterPro:IPR001269" /db_xref="InterPro:IPR004652" /db_xref="InterPro:IPR013785" /db_xref="InterPro:IPR018517" /db_xref="InterPro:IPR024036" /db_xref="InterPro:IPR035587" /db_xref="SubtiList:BG10143" /db_xref="UniProtKB/Swiss-Prot:P37567" /translation="MFKIGDIQLKNRVVLAPMAGVCNSAFRLTVKEFGAGLVCAEMVS DKAILYNNARTMGMLYIDEREKPLSLQIFGGKKETLVEAAKFVDQNTTADIIDINMGC PVPKITKCDAGAKWLLDPDKIYEMVSAVVDAVNKPVTVKMRMGWDEDHIFAVKNAQAV ERAGGKAVALHGRTRVQMYEGTANWDIIKEVKQSVSIPVIGNGDVKTPQDAKRMLDET GVDGVMIGRAALGNPWMIYRTVQYLETGKLKEEPQVREKMAVCKLHLDRLIDLKGENV AVREMRKHAAWYLKGVKGNANVRNEINHCETREEFVQLLDAFTVEVEAKELQNAKVG* " gene 87634..88635 /gene="dusB" /locus_tag="BSU_00810" /old_locus_tag="BSU00810" S_feature complement(88050..89566) /Source="Nicolas_S_feature" /locus_tag="new_88050_89566_c" /HighExp="LoTm, C30, S6, S8, S5, S7, S3, S4, C90, G135" /AntisenseName="dusB" /AntisenseCor="-0.60218706634778196" /AntisenseRegPval="-27.2" /CDS_PredictionProba="NA" /TUshortSig="SigEF" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S41" S_feature 88636..88726 /Source="Nicolas_S_feature" /locus_tag="new_88636_88726" /HighExp="H2O2, G180, G150, Paraq, G135, Oxctl, Diami, C30, LBGexp, C90" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="0.998, 0.998" /TUlongSig="SigA, SigI, SigA, SigEF, SigA, SigA, SigA" /TUlongPSig="0.621, 0.787, 1, 0.995, 1, 0.999, 1" /label="S42" CDS 88727..90226 /gene="lysS" /locus_tag="BSU_00820" /old_locus_tag="BSU00820" /EC_number="6.1.1.6" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:12682299, 14623972, 20649968" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12682299, 14623972, 20649968; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="lysyl-tRNA synthetase" /protein_id="NP_387963.1" /db_xref="EnsemblGenomes-Gn:BSU00820" /db_xref="EnsemblGenomes-Tr:CAB11858" /db_xref="GOA:P37477" /db_xref="InterPro:IPR002313" /db_xref="InterPro:IPR004364" /db_xref="InterPro:IPR004365" /db_xref="InterPro:IPR006195" /db_xref="InterPro:IPR012340" /db_xref="InterPro:IPR018149" /db_xref="InterPro:IPR034762" /db_xref="SubtiList:BG10144" /db_xref="UniProtKB/Swiss-Prot:P37477" /translation="MSQEEHNHEELNDQLQVRRDKMNQLRDNGIDPFGARFERTHQSQ EVISAYQDLTKEELEEKAIEVTIAGRMMTKRGKGKAGFAHLQDLEGQIQIYVRKDSVG DDQYEIFKSSDLGDLIGVTGKVFKTNVGELSVKATSFELLTKALRPLPDKYHGLKDVE QRYRQRYLDLIVNPDSKHTFITRSKIIQAMRRYLDDHGYLEVETPTMHSIPGGASARP FITHHNALDIPLYMRIAIELHLKRLIVGGLEKVYEIGRVFRNEGVSTRHNPEFTMIEL YEAYADYKDIMSLTENLVAHIAQEVLGTTTIQYGEEQIDLKPEWKRIHMVDAVKEATG VDFWEEVTVEQAREYAKEHEVEIKDSMTVGHIINEFFEQKIEETLIQPTFIYGHPVEI SPLAKKNPEDPRFTDRFELFIVGREHANAFTELNDPIDQRERFEAQLKEREAGNDEAH LMDEDFVEALEYGMPPTGGLGIGIDRLVMLLTNAPSIRDVLLFPQMRQR*" gene 88727..90226 /gene="lysS" /locus_tag="BSU_00820" /old_locus_tag="BSU00820" promotor_-10 complement(89550..89568) /Source="Nicolas_upshift_promotors" /id="U77" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1081 /SigmaFactorBS="ttcttgggcgatatgagcgacaaggttttcagttaagCTCAT GatatctttatagtccGCATATGCTTCATATAACTcaatcattgtaaattcagggtta t" /listShort="S41" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(89566) /Source="Nicolas_upshifts" /id="U77" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1081 /SigmaFactorBS="ttcttgggcgatatgagcgacaaggttttcagttaagCTCAT GatatctttatagtccGCATATGCTTCATATAACTcaatcattgtaaattcagggtta t" /listShort="S41" /GFF_Attribute="listLong" promotor_-35 complement(89584..89589) /Source="Nicolas_upshift_promotors" /id="U77" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1081 /SigmaFactorBS="ttcttgggcgatatgagcgacaaggttttcagttaagCTCAT GatatctttatagtccGCATATGCTTCATATAACTcaatcattgtaaattcagggtta t" /listShort="S41" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 90207 /Source="Nicolas_upshifts" /id="D36" /incds=0 /nref=104 /ntot=219 /MaxReadThrough="4.49559" /MaxDrop="4.89484" /score="4.33485487" /energy="-18.1" /TU="U76" /idTUdmin="U74" /TUdmin=3 /isTUend="TRUE" promotor_-35 90302..90309 /Source="Nicolas_upshift_promotors" /id="U78" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.999000999001" /psig=1 /xcortree=2623 /SigmaFactorBS="gatgccgctctttttaaatcccttagtatttcttcaaaaaaa ctATTGCACTattatttactaggTGGTATATTATTATTCGTTGccgctaaacaaggcg a" /listShort="S43, rrnJ-16S, rrnJ-23S, rrnJ-5S, trnJ-Val, trnJ-Thr, trnJ-Lys, trnJ-Leu1, trnJ-Gly, trnJ-Leu2, trnJ-Arg, trnJ-Pro" /GFF_Attribute="listLong" /label="promotor_-35" S_feature 90318..90535 /Source="Nicolas_S_feature" /locus_tag="new_90318_90535" /HighExp="LBGstat, H2O2, Oxctl, Diami, dia15, Paraq, MG 25, Heat, MG 15, UNK1" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="SigA, SigA, SigA, SigA, SigA, SigA" /TUlongPSig="0.998, 0.998, 1, 1, 0.999, 1" /label="S43" upshifts 90318 /Source="Nicolas_upshifts" /id="U78" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.999000999001" /psig=1 /xcortree=2623 /SigmaFactorBS="gatgccgctctttttaaatcccttagtatttcttcaaaaaaa ctATTGCACTattatttactaggTGGTATATTATTATTCGTTGccgctaaacaaggcg a" /listShort="S43, rrnJ-16S, rrnJ-23S, rrnJ-5S, trnJ-Val, trnJ-Thr, trnJ-Lys, trnJ-Leu1, trnJ-Gly, trnJ-Leu2, trnJ-Arg, trnJ-Pro" /GFF_Attribute="listLong" promotor_-10 90323..90342 /Source="Nicolas_upshift_promotors" /id="U78" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.999000999001" /psig=1 /xcortree=2623 /SigmaFactorBS="gatgccgctctttttaaatcccttagtatttcttcaaaaaaa ctATTGCACTattatttactaggTGGTATATTATTATTCGTTGccgctaaacaaggcg a" /listShort="S43, rrnJ-16S, rrnJ-23S, rrnJ-5S, trnJ-Val, trnJ-Thr, trnJ-Lys, trnJ-Leu1, trnJ-Gly, trnJ-Leu2, trnJ-Arg, trnJ-Pro" /GFF_Attribute="listLong" /label="promotor_-10" downshifts complement(90368) /Source="Nicolas_upshifts" /id="D37" /incds=0 /nref=3 /ntot=51 /MaxReadThrough="3.16217" /MaxDrop="5.0092" /score="18.6635354" /energy="-16.9" /TU="NA" /idTUdmin="U77" /TUdmin="-2288" /isTUend="FALSE" rRNA 90536..92089 /gene="rrnJ-16S" /locus_tag="BSU_rRNA_6" /product="ribosomal RNA-16S" /note="Evidence 1a: Function from experimental evidences in the studied strain; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene 90536..92089 /gene="rrnJ-16S" /locus_tag="BSU_rRNA_6" rRNA 92254..95181 /gene="rrnJ-23S" /locus_tag="BSU_rRNA_7" /product="ribosomal RNA-23S" /note="Evidence 1a: Function from experimental evidences in the studied strain; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene 92254..95181 /gene="rrnJ-23S" /locus_tag="BSU_rRNA_7" rRNA 95237..95354 /gene="rrnJ-5S" /locus_tag="BSU_rRNA_8" /product="ribosomal RNA-5S" /note="Evidence 1a: Function from experimental evidences in the studied strain; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene 95237..95354 /gene="rrnJ-5S" /locus_tag="BSU_rRNA_8" tRNA 95375..95450 /gene="trnJ-Val" /locus_tag="BSU_tRNA_12" /product="tRNA-Val" /inference="profile:tRNAscan:1.23" /note="transfer RNA-Val(UAC); Evidence 2a: Function from experimental evidences in other organisms; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene 95375..95450 /gene="trnJ-Val" /locus_tag="BSU_tRNA_12" tRNA 95455..95530 /gene="trnJ-Thr" /locus_tag="BSU_tRNA_13" /product="tRNA-Thr" /inference="profile:tRNAscan:1.23" /note="transfer RNA-Thr(UGU); Evidence 2a: Function from experimental evidences in other organisms; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene 95455..95530 /gene="trnJ-Thr" /locus_tag="BSU_tRNA_13" tRNA 95567..95642 /gene="trnJ-Lys" /locus_tag="BSU_tRNA_14" /product="tRNA-Lys" /inference="profile:tRNAscan:1.23" /note="transfer RNA-Lys(UUU); Evidence 2a: Function from experimental evidences in other organisms; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene 95567..95642 /gene="trnJ-Lys" /locus_tag="BSU_tRNA_14" tRNA 95649..95731 /gene="trnJ-Leu1" /locus_tag="BSU_tRNA_15" /product="tRNA-Leu" /inference="profile:tRNAscan:1.23" /note="transfer RNA-Leu(UAG); Evidence 2a: Function from experimental evidences in other organisms; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene 95649..95731 /gene="trnJ-Leu1" /locus_tag="BSU_tRNA_15" tRNA 95772..95846 /gene="trnJ-Gly" /locus_tag="BSU_tRNA_16" /product="tRNA-Gly" /inference="profile:tRNAscan:1.23" /note="transfer RNA-Gly(GCC); Evidence 2a: Function from experimental evidences in other organisms; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene 95772..95846 /gene="trnJ-Gly" /locus_tag="BSU_tRNA_16" tRNA 95861..95946 /gene="trnJ-Leu2" /locus_tag="BSU_tRNA_17" /product="tRNA-Leu" /inference="profile:tRNAscan:1.23" /note="transfer RNA-Leu(UAA); Evidence 2a: Function from experimental evidences in other organisms; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene 95861..95946 /gene="trnJ-Leu2" /locus_tag="BSU_tRNA_17" tRNA 95956..96032 /gene="trnJ-Arg" /locus_tag="BSU_tRNA_18" /product="tRNA-Arg" /inference="profile:tRNAscan:1.23" /note="arginine transfer RNA(ACG); Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 27749819; Product type n : RNA" /function="16.2: Construct biomass (Anabolism)" gene 95956..96032 /gene="trnJ-Arg" /locus_tag="BSU_tRNA_18" tRNA 96060..96136 /gene="trnJ-Pro" /locus_tag="BSU_tRNA_19" /product="tRNA-Pro" /inference="profile:tRNAscan:1.23" /note="transfer RNA-Pro(UGG); Evidence 2a: Function from experimental evidences in other organisms; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene 96060..96136 /gene="trnJ-Pro" /locus_tag="BSU_tRNA_19" tRNA 96146..96221 /gene="trnJ-Ala" /locus_tag="BSU_tRNA_20" /product="tRNA-Ala" /inference="profile:tRNAscan:1.23" /note="transfer RNA-Ala(UGC); Evidence 2a: Function from experimental evidences in other organisms; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene 96146..96221 /gene="trnJ-Ala" /locus_tag="BSU_tRNA_20" rRNA 96392..97945 /gene="rrnW-16S" /locus_tag="BSU_rRNA_9" /product="ribosomal RNA-16S" /note="Evidence 1a: Function from experimental evidences in the studied strain; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene 96392..97945 /gene="rrnW-16S" /locus_tag="BSU_rRNA_9" rRNA 98110..101037 /gene="rrnW-23S" /locus_tag="BSU_rRNA_10" /product="ribosomal RNA-23S" /note="Evidence 1a: Function from experimental evidences in the studied strain; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene 98110..101037 /gene="rrnW-23S" /locus_tag="BSU_rRNA_10" rRNA 101093..101211 /gene="rrnW-5S" /locus_tag="BSU_rRNA_11" /product="ribosomal RNA-5S" /note="Evidence 1a: Function from experimental evidences in the studied strain; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene 101093..101211 /gene="rrnW-5S" /locus_tag="BSU_rRNA_11" S_feature 101212..101289 /Source="Nicolas_S_feature" /locus_tag="new_101212_101289" /HighExp="G135, G180, G150, Cold, Paraq, Oxctl, H2O2, C30, BMM, Lbexp" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="NA" /TUshortPSig="NA" /TUlongSig="NA" /TUlongPSig="NA" /label="S44" promotor_-35 101259..101262 /Source="Nicolas_upshift_promotors" /id="U79" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.37962037962038" /psig="0.947052947052947" /xcortree=1441 /SigmaFactorBS="gctgggttttttgtattttggtttattgGTATcataaaattc cacttAACTGTATAATATAATAACTttataccgaattttaaatcagcaatcaggtttt g" /listShort="ctsR, mcsA, mcsB, clpC" /listLong="radA, disA, S45, yacL, ispD, ispF, gltX, S46, cysE, cysS, mrnC, rlmB, yacP, sigH, S47, rpmGB, secE, S48, nusG, S49, rplK, S50, rplA, NA, rplJ, rplL, ybxB, S51, rpoB, rpoC, S52, rplGB, S53, rpsL, rpsG, fusA, S54, tufA, ybaC, S55, rpsJ, rplC, rplD, rplW, rplB, rpsS, rplV, rpsC, rplP, rpmC, rpsQ, rplNA, rplX, rplE, rpsNA, rpsH, rplF, rplR, rpsE, rpmD, rplO, secY, adk, mapA, ybzG, infA, rpmJ, rpsM, rpsK, S56, rpoA, rplQ, S57, ybxA, ybaE, ybaF, truA, NA, rplM, rpsI, S59, ybaJ" /label="promotor_-35" promotor_-10 101278..101297 /Source="Nicolas_upshift_promotors" /id="U79" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.37962037962038" /psig="0.947052947052947" /xcortree=1441 /SigmaFactorBS="gctgggttttttgtattttggtttattgGTATcataaaattc cacttAACTGTATAATATAATAACTttataccgaattttaaatcagcaatcaggtttt g" /listShort="ctsR, mcsA, mcsB, clpC" /listLong="radA, disA, S45, yacL, ispD, ispF, gltX, S46, cysE, cysS, mrnC, rlmB, yacP, sigH, S47, rpmGB, secE, S48, nusG, S49, rplK, S50, rplA, NA, rplJ, rplL, ybxB, S51, rpoB, rpoC, S52, rplGB, S53, rpsL, rpsG, fusA, S54, tufA, ybaC, S55, rpsJ, rplC, rplD, rplW, rplB, rpsS, rplV, rpsC, rplP, rpmC, rpsQ, rplNA, rplX, rplE, rpsNA, rpsH, rplF, rplR, rpsE, rpmD, rplO, secY, adk, mapA, ybzG, infA, rpmJ, rpsM, rpsK, S56, rpoA, rplQ, S57, ybxA, ybaE, ybaF, truA, NA, rplM, rpsI, S59, ybaJ" /label="promotor_-10" upshifts 101291 /Source="Nicolas_upshifts" /id="U79" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.37962037962038" /psig="0.947052947052947" /xcortree=1441 /SigmaFactorBS="gctgggttttttgtattttggtttattgGTATcataaaattc cacttAACTGTATAATATAATAACTttataccgaattttaaatcagcaatcaggtttt g" /listShort="ctsR, mcsA, mcsB, clpC" /listLong="radA, disA, S45, yacL, ispD, ispF, gltX, S46, cysE, cysS, mrnC, rlmB, yacP, sigH, S47, rpmGB, secE, S48, nusG, S49, rplK, S50, rplA, NA, rplJ, rplL, ybxB, S51, rpoB, rpoC, S52, rplGB, S53, rpsL, rpsG, fusA, S54, tufA, ybaC, S55, rpsJ, rplC, rplD, rplW, rplB, rpsS, rplV, rpsC, rplP, rpmC, rpsQ, rplNA, rplX, rplE, rpsNA, rpsH, rplF, rplR, rpsE, rpmD, rplO, secY, adk, mapA, ybzG, infA, rpmJ, rpsM, rpsK, S56, rpoA, rplQ, S57, ybxA, ybaE, ybaF, truA, NA, rplM, rpsI, S59, ybaJ" promotor_-35 101325..101331 /Source="Nicolas_upshift_promotors" /id="U80" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=150 /SigmaFactorBS="ctttataccgaattttaaatcagcaatcaGGTTTTGtggacc gggaaaaTGGAAATAATGAAGGATAGAgcgagaaagttgaaaattctcgagaaacggc t" /listShort="ctsR, mcsA, mcsB, clpC, radA, disA, S45, yacL, ispD, ispF" /listLong="gltX, S46, cysE, cysS, mrnC, rlmB, yacP, sigH, S47, rpmGB, secE, S48, nusG, S49, rplK, S50, rplA, NA, rplJ, rplL, ybxB, S51, rpoB, rpoC, S52, rplGB, S53, rpsL, rpsG, fusA, S54, tufA, ybaC" /label="promotor_-35" promotor_-10 101345..101364 /Source="Nicolas_upshift_promotors" /id="U80" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=150 /SigmaFactorBS="ctttataccgaattttaaatcagcaatcaGGTTTTGtggacc gggaaaaTGGAAATAATGAAGGATAGAgcgagaaagttgaaaattctcgagaaacggc t" /listShort="ctsR, mcsA, mcsB, clpC, radA, disA, S45, yacL, ispD, ispF" /listLong="gltX, S46, cysE, cysS, mrnC, rlmB, yacP, sigH, S47, rpmGB, secE, S48, nusG, S49, rplK, S50, rplA, NA, rplJ, rplL, ybxB, S51, rpoB, rpoC, S52, rplGB, S53, rpsL, rpsG, fusA, S54, tufA, ybaC" /label="promotor_-10" upshifts 101356 /Source="Nicolas_upshifts" /id="U80" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=150 /SigmaFactorBS="ctttataccgaattttaaatcagcaatcaGGTTTTGtggacc gggaaaaTGGAAATAATGAAGGATAGAgcgagaaagttgaaaattctcgagaaacggc t" /listShort="ctsR, mcsA, mcsB, clpC, radA, disA, S45, yacL, ispD, ispF" /listLong="gltX, S46, cysE, cysS, mrnC, rlmB, yacP, sigH, S47, rpmGB, secE, S48, nusG, S49, rplK, S50, rplA, NA, rplJ, rplL, ybxB, S51, rpoB, rpoC, S52, rplGB, S53, rpsL, rpsG, fusA, S54, tufA, ybaC" promotor_-35 101371..101378 /Source="Nicolas_upshift_promotors" /id="U81" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.736263736263736" /psig=1 /xcortree=2024 /SigmaFactorBS="atggaaataatgaaggatagagcgagaAAGTTGAAaattctc gagaaaCGGCTTATAGTAAGATTAAAgtcaaatatagtcaaagtcagtaaaggagggg g" /listShort="ctsR, mcsA, mcsB, clpC, radA, disA, S45, yacL, ispD, ispF" /listLong="gltX, S46, cysE, cysS, mrnC, rlmB, yacP, sigH, S47, rpmGB, secE, S48, nusG, S49, rplK, S50, rplA, NA, rplJ, rplL, ybxB, S51, rpoB, rpoC, S52, rplGB, S53, rpsL, rpsG, fusA, S54, tufA, ybaC, S55, rpsJ, rplC, rplD, rplW, rplB, rpsS, rplV, rpsC, rplP, rpmC, rpsQ, rplNA, rplX, rplE, rpsNA, rpsH, rplF, rplR, rpsE, rpmD, rplO, secY, adk, mapA, ybzG, infA, rpmJ, rpsM, rpsK, S56, rpoA, rplQ, S57, ybxA, ybaE, ybaF, truA, NA, rplM, rpsI, S59, ybaJ" /label="promotor_-35" promotor_-10 101392..101411 /Source="Nicolas_upshift_promotors" /id="U81" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.736263736263736" /psig=1 /xcortree=2024 /SigmaFactorBS="atggaaataatgaaggatagagcgagaAAGTTGAAaattctc gagaaaCGGCTTATAGTAAGATTAAAgtcaaatatagtcaaagtcagtaaaggagggg g" /listShort="ctsR, mcsA, mcsB, clpC, radA, disA, S45, yacL, ispD, ispF" /listLong="gltX, S46, cysE, cysS, mrnC, rlmB, yacP, sigH, S47, rpmGB, secE, S48, nusG, S49, rplK, S50, rplA, NA, rplJ, rplL, ybxB, S51, rpoB, rpoC, S52, rplGB, S53, rpsL, rpsG, fusA, S54, tufA, ybaC, S55, rpsJ, rplC, rplD, rplW, rplB, rpsS, rplV, rpsC, rplP, rpmC, rpsQ, rplNA, rplX, rplE, rpsNA, rpsH, rplF, rplR, rpsE, rpmD, rplO, secY, adk, mapA, ybzG, infA, rpmJ, rpsM, rpsK, S56, rpoA, rplQ, S57, ybxA, ybaE, ybaF, truA, NA, rplM, rpsI, S59, ybaJ" /label="promotor_-10" upshifts 101404 /Source="Nicolas_upshifts" /id="U81" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.736263736263736" /psig=1 /xcortree=2024 /SigmaFactorBS="atggaaataatgaaggatagagcgagaAAGTTGAAaattctc gagaaaCGGCTTATAGTAAGATTAAAgtcaaatatagtcaaagtcagtaaaggagggg g" /listShort="ctsR, mcsA, mcsB, clpC, radA, disA, S45, yacL, ispD, ispF" /listLong="gltX, S46, cysE, cysS, mrnC, rlmB, yacP, sigH, S47, rpmGB, secE, S48, nusG, S49, rplK, S50, rplA, NA, rplJ, rplL, ybxB, S51, rpoB, rpoC, S52, rplGB, S53, rpsL, rpsG, fusA, S54, tufA, ybaC, S55, rpsJ, rplC, rplD, rplW, rplB, rpsS, rplV, rpsC, rplP, rpmC, rpsQ, rplNA, rplX, rplE, rpsNA, rpsH, rplF, rplR, rpsE, rpmD, rplO, secY, adk, mapA, ybzG, infA, rpmJ, rpsM, rpsK, S56, rpoA, rplQ, S57, ybxA, ybaE, ybaF, truA, NA, rplM, rpsI, S59, ybaJ" CDS 101449..101913 /gene="ctsR" /locus_tag="BSU_00830" /old_locus_tag="BSU00830" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:2120829, 9852015, 11069659, 12618461, 16163393, 20852588, 24465625, 27388279" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 2120829, 9852015, 11069659, 12618461, 16163393, 20852588, 24465625, 27388279; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator of class III stress genes" /protein_id="NP_387964.1" /db_xref="EnsemblGenomes-Gn:BSU00830" /db_xref="EnsemblGenomes-Tr:CAB11859" /db_xref="GOA:P37568" /db_xref="InterPro:IPR008463" /db_xref="SubtiList:BG10145" /db_xref="UniProtKB/Swiss-Prot:P37568" /translation="MGHNISDIIEQYLKRVLDQNGKEILEIKRSEIADKFQCVPSQIN YVINTRFTSERGYIVESKRGGGGYIRIIKIKMNNEVVLINNIISQINTHLSQAASDDI ILRLLEDKVISEREAKMMVSVMDRSVLHIDLPERDELRARMMKAMLTSLKLK*" gene 101449..101913 /gene="ctsR" /locus_tag="BSU_00830" /old_locus_tag="BSU00830" misc_feature complement(101560..101564) /Source="Nicolas_upshift_promotors" /id="U82" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.811188811188811" /psig="0.0769230769230769" /xcortree=50 /SigmaFactorBS="caacaatatatcctctttcgcttgtaaatctggtgttgatga cataatttatttgggaaggaACGCAttgaaatttatctgcaatttcacttcgtttaat c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(101566) /Source="Nicolas_upshifts" /id="U82" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.811188811188811" /psig="0.0769230769230769" /xcortree=50 /SigmaFactorBS="caacaatatatcctctttcgcttgtaaatctggtgttgatga cataatttatttgggaaggaACGCAttgaaatttatctgcaatttcacttcgtttaat c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" CDS 101927..102484 /gene="mcsA" /locus_tag="BSU_00840" /old_locus_tag="BSU00840" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:16163393, 19189946, 24947607" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16163393, 19189946, 24947607; Product type f: factor" /codon_start=1 /transl_table=11 /product="activator of protein kinase McsB" /protein_id="NP_387965.1" /db_xref="EnsemblGenomes-Gn:BSU00840" /db_xref="EnsemblGenomes-Tr:CAB11860" /db_xref="GOA:P37569" /db_xref="InterPro:IPR001943" /db_xref="InterPro:IPR025542" /db_xref="InterPro:IPR029037" /db_xref="InterPro:IPR036876" /db_xref="SubtiList:BG10146" /db_xref="UniProtKB/Swiss-Prot:P37569" /translation="MICQECHERPATFHFTKVVNGEKIEVHICEQCAKENSDSYGISA NQGFSIHNLLSGLLNMDSSFQNAGTQMFSHSEQISACPKCGMTFQQFRKIGRFGCSEC YKTFHSNITPILRKVHSGNTVHAGKIPKRIGGNLHVRRQIDMLKKELESLIHQEEFEN AAHVRDQIRLLEQSLKSTDSEEEQE*" gene 101927..102484 /gene="mcsA" /locus_tag="BSU_00840" /old_locus_tag="BSU00840" CDS 102484..103575 /gene="mcsB" /locus_tag="BSU_00850" /old_locus_tag="BSU00850" /EC_number="2.7.3.3" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:16163393, 17380125, 19189946, 21622759, 25610436, 27749819" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16163393, 17380125, 19189946, 21622759, 25610436, 27749819; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="protein arginine kinase" /protein_id="NP_387966.1" /db_xref="EnsemblGenomes-Gn:BSU00850" /db_xref="EnsemblGenomes-Tr:CAB11861" /db_xref="GOA:P37570" /db_xref="InterPro:IPR000749" /db_xref="InterPro:IPR014746" /db_xref="InterPro:IPR022414" /db_xref="InterPro:IPR022415" /db_xref="InterPro:IPR023660" /db_xref="SubtiList:BG10147" /db_xref="UniProtKB/Swiss-Prot:P37570" /translation="MSLKHFIQDALSSWMKQKGPESDIVLSSRIRLARNFEHIRFPTR YSNEEASSIIQQFEDQFSEQEIPGIGKFVLIRMNDAQPLEKRVLVEKHLISPNLTESP FGGCLLSENEEVSVMLNEEDHIRIQCLFPGFQLLEAMKAANQVDDWIEEKVDYAFNEQ RGYLTSCPTNVGTGLRASVMMHLPALVLTRQINRIIPAINQLGLVVRGIYGEGSEAVG NIFQISNQITLGKSEQDIVEDLNSVAAQLIEQERSAREAIYQTSKIELEDRVYRSYGV LSNCRMIESKETAKCLSDVRLGIDLGIIKGLSSNILNELMILTQPGFLQQYSGGALRP NERDIRRAALIRERLHLEMNGKRQEDESI*" gene 102484..103575 /gene="mcsB" /locus_tag="BSU_00850" /old_locus_tag="BSU00850" CDS 103572..106004 /gene="clpC" /locus_tag="BSU_00860" /old_locus_tag="BSU00860" /function="16.6: Maintain" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:12354604, 15529410, 16525504, 26735940, 27749819" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12354604, 15529410, 16525504, 26735940, 27749819; Product type f: factor" /codon_start=1 /transl_table=11 /product="class III stress response-related ATPase, AAA+ superfamily" /protein_id="NP_387967.1" /db_xref="EnsemblGenomes-Gn:BSU00860" /db_xref="EnsemblGenomes-Tr:CAB11862" /db_xref="GOA:P37571" /db_xref="InterPro:IPR001270" /db_xref="InterPro:IPR001943" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR003959" /db_xref="InterPro:IPR004176" /db_xref="InterPro:IPR018368" /db_xref="InterPro:IPR019489" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR028299" /db_xref="InterPro:IPR036628" /db_xref="PDB:2K77" /db_xref="PDB:2Y1Q" /db_xref="PDB:2Y1R" /db_xref="PDB:3J3R" /db_xref="PDB:3J3S" /db_xref="PDB:3J3T" /db_xref="PDB:3J3U" /db_xref="PDB:3PXG" /db_xref="PDB:3PXI" /db_xref="PDB:5HBN" /db_xref="SubtiList:BG10148" /db_xref="UniProtKB/Swiss-Prot:P37571" /translation="MMFGRFTERAQKVLALAQEEALRLGHNNIGTEHILLGLVREGEG IAAKALQALGLGSEKIQKEVESLIGRGQEMSQTIHYTPRAKKVIELSMDEARKLGHSY VGTEHILLGLIREGEGVAARVLNNLGVSLNKARQQVLQLLGSNETGSSAAGTNSNANT PTLDSLARDLTAIAKEDSLDPVIGRSKEIQRVIEVLSRRTKNNPVLIGEPGVGKTAIA EGLAQQIINNEVPEILRDKRVMTLDMGTVVAGTKYRGEFEDRLKKVMDEIRQAGNIIL FIDELHTLIGAGGAEGAIDASNILKPSLARGELQCIGATTLDEYRKYIEKDAALERRF QPIQVDQPSVDESIQILQGLRDRYEAHHRVSITDDAIEAAVKLSDRYISDRFLPDKAI DLIDEAGSKVRLRSFTTPPNLKELEQKLDEVRKEKDAAVQSQEFEKAASLRDTEQRLR EQVEDTKKSWKEKQGQENSEVTVDDIAMVVSSWTGVPVSKIAQTETDKLLNMENILHS RVIGQDEAVVAVAKAVRRARAGLKDPKRPIGSFIFLGPTGVGKTELARALAESIFGDE ESMIRIDMSEYMEKHSTSRLVGSPPGYVGYDEGGQLTEKVRRKPYSVVLLDEIEKAHP DVFNILLQVLEDGRLTDSKGRTVDFRNTILIMTSNVGASELKRNKYVGFNVQDETQNH KDMKDKVMGELKRAFRPEFINRIDEIIVFHSLEKKHLTEIVSLMSDQLTKRLKEQDLS IELTDAAKAKVAEEGVDLEYGARPLRRAIQKHVEDRLSEELLRGNIHKGQHIVLDVED GEFVVKTTAKTN*" gene 103572..106004 /gene="clpC" /locus_tag="BSU_00860" /old_locus_tag="BSU00860" downshifts 105999 /Source="Nicolas_upshifts" /id="D38" /incds=0 /nref=57 /ntot=245 /MaxReadThrough="6.69446" /MaxDrop="4.4703" /score="-8.32149463" /energy="-11.7" /TU="U80,U81" /idTUdmin="U79" /TUdmin="-1" /isTUend="TRUE" CDS 106096..107472 /gene="radA" /locus_tag="BSU_00870" /old_locus_tag="BSU00870" /EC_number="2.1.1.63" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2b: Function from indirect experimental evidences (e.g. phenotypes); PubMedId: 10931349, 11810266, 15317759, 25616256; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="DNA repair protein; 6-O-methylguanine-DNA methyltransferase" /protein_id="NP_387968.1" /db_xref="EnsemblGenomes-Gn:BSU00870" /db_xref="EnsemblGenomes-Tr:CAB11863" /db_xref="GOA:P37572" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR004504" /db_xref="InterPro:IPR014721" /db_xref="InterPro:IPR020568" /db_xref="InterPro:IPR020588" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG10149" /db_xref="UniProtKB/Swiss-Prot:P37572" /translation="MAKTKSKFICQSCGYESPKWMGKCPGCGAWNTMVEEMIKKAPAN RRAAFSHSVQTVQKPSPITSIETSEEPRVKTQLGEFNRVLGGGVVKGSLVLIGGDPGI GKSTLLLQVSAQLSGSSNSVLYISGEESVKQTKLRADRLGINNPSLHVLSETDMEYIS SAIQEMNPSFVVVDSIQTVYQSDITSAPGSVSQVRECTAELMKIAKTKGIPIFIVGHV TKEGSIAGPRLLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEMGIFEMREEGLTE VLNPSEIFLEERSAGSAGSSITASMEGTRPILVEIQALISPTSFGNPRRMATGIDHNR VSLLMAVLEKRVGLLLQNQDAYLKVAGGVKLDEPAIDLAIVISIASSFRDTPPNPADC FIGEVGLTGEVRRVSRIEQRVKEAAKLGFKRMIIPAANLDGWTKPKGIEVIGVANVAE ALRTSLGG*" gene 106096..107472 /gene="radA" /locus_tag="BSU_00870" /old_locus_tag="BSU00870" promotor_-35 106551..106560 /Source="Nicolas_upshift_promotors" /id="U83" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1648 /SigmaFactorBS="ctcggcattaataatccgtcactgcatgttttatcTGAAACC GATatggagtatattTCGTCTGCTATACAAGagatgaatccatcgtttgtcgttgttg a" /listShort="disA, S45, yacL, ispD, ispF, gltX, S46, cysE, cysS, mrnC, rlmB, yacP" /listLong="sigH, S47, rpmGB, secE, S48, nusG, S49, rplK, S50, rplA, NA, rplJ, rplL, ybxB, S51, rpoB, rpoC, S52, rplGB, S53, rpsL, rpsG, fusA, S54, tufA, ybaC, S55, rpsJ, rplC, rplD, rplW, rplB, rpsS, rplV, rpsC, rplP, rpmC, rpsQ, rplNA, rplX, rplE, rpsNA, rpsH, rplF, rplR, rpsE, rpmD, rplO, secY, adk, mapA, ybzG, infA, rpmJ, rpsM, rpsK, S56, rpoA, rplQ, S57, ybxA, ybaE, ybaF, truA, NA, rplM, rpsI, S59, ybaJ" /label="promotor_-35" promotor_-10 106573..106588 /Source="Nicolas_upshift_promotors" /id="U83" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1648 /SigmaFactorBS="ctcggcattaataatccgtcactgcatgttttatcTGAAACC GATatggagtatattTCGTCTGCTATACAAGagatgaatccatcgtttgtcgttgttg a" /listShort="disA, S45, yacL, ispD, ispF, gltX, S46, cysE, cysS, mrnC, rlmB, yacP" /listLong="sigH, S47, rpmGB, secE, S48, nusG, S49, rplK, S50, rplA, NA, rplJ, rplL, ybxB, S51, rpoB, rpoC, S52, rplGB, S53, rpsL, rpsG, fusA, S54, tufA, ybaC, S55, rpsJ, rplC, rplD, rplW, rplB, rpsS, rplV, rpsC, rplP, rpmC, rpsQ, rplNA, rplX, rplE, rpsNA, rpsH, rplF, rplR, rpsE, rpmD, rplO, secY, adk, mapA, ybzG, infA, rpmJ, rpsM, rpsK, S56, rpoA, rplQ, S57, ybxA, ybaE, ybaF, truA, NA, rplM, rpsI, S59, ybaJ" /label="promotor_-10" upshifts 106576 /Source="Nicolas_upshifts" /id="U83" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1648 /SigmaFactorBS="ctcggcattaataatccgtcactgcatgttttatcTGAAACC GATatggagtatattTCGTCTGCTATACAAGagatgaatccatcgtttgtcgttgttg a" /listShort="disA, S45, yacL, ispD, ispF, gltX, S46, cysE, cysS, mrnC, rlmB, yacP" /listLong="sigH, S47, rpmGB, secE, S48, nusG, S49, rplK, S50, rplA, NA, rplJ, rplL, ybxB, S51, rpoB, rpoC, S52, rplGB, S53, rpsL, rpsG, fusA, S54, tufA, ybaC, S55, rpsJ, rplC, rplD, rplW, rplB, rpsS, rplV, rpsC, rplP, rpmC, rpsQ, rplNA, rplX, rplE, rpsNA, rpsH, rplF, rplR, rpsE, rpmD, rplO, secY, adk, mapA, ybzG, infA, rpmJ, rpsM, rpsK, S56, rpoA, rplQ, S57, ybxA, ybaE, ybaF, truA, NA, rplM, rpsI, S59, ybaJ" CDS 107476..108558 /gene="disA" /locus_tag="BSU_00880" /old_locus_tag="BSU00880" /function="16.3: Control" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:16713562, 21566650, 24939848, 25616256, 27074767, 27150552, 28511132, 28961460" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16713562, 21566650, 24939848, 25616256, 27074767, 27150552, 28511132, 28961460; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="diadenylate cyclase; DNA integrity scanning protein; cell cycle checkpoint DNA scanning protein" /protein_id="NP_387969.1" /db_xref="EnsemblGenomes-Gn:BSU00880" /db_xref="EnsemblGenomes-Tr:CAB11864" /db_xref="GOA:P37573" /db_xref="InterPro:IPR003390" /db_xref="InterPro:IPR010994" /db_xref="InterPro:IPR018906" /db_xref="InterPro:IPR023763" /db_xref="InterPro:IPR036888" /db_xref="SubtiList:BG10150" /db_xref="UniProtKB/Swiss-Prot:P37573" /translation="MEKEKKGAKHELDLSSILQFVAPGTPLRAGMENVLRANTGGLIV VGYNDKVKEVVDGGFHINTAFSPAHLYELAKMDGAIILSDSGQKILYANTQLMPDATI SSSETGMRHRTAERVAKQTGCLVIAISERRNVITLYQENMKYTLKDIGFILTKANQAI QTLEKYKTILDKTINALNALEFEELVTFSDVLSVMHRYEMVLRIKNEINMYIKELGTE GHLIKLQVIELITDMEEEAALFIKDYVKEKIKDPFVLLKELQDMSSYDLLDDSIVYKL LGYPASTNLDDYVLPRGYRLLNKIPRLPMPIVENVVEAFGVLPRIIEASAEELDEVEG IGEVRAQKIKKGLKRLQEKHYLDRQL*" gene 107476..108558 /gene="disA" /locus_tag="BSU_00880" /old_locus_tag="BSU00880" S_feature 108559..108673 /Source="Nicolas_S_feature" /locus_tag="new_108559_108673" /HighExp="Etha, Salt, Heat, dia15, Diami, M9-stat, B60, T-0.40H, T-1.10H, HiTm" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigWXY, SigA, SigB" /TUshortPSig="1, 1, 1" /TUlongSig="SigA" /TUlongPSig="0.947" /label="S45" CDS 108674..109774 /gene="yacL" /locus_tag="BSU_00890" /old_locus_tag="BSU00890" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 26999498; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative membrane protein possibly involved in RNA binding" /protein_id="NP_387970.1" /db_xref="EnsemblGenomes-Gn:BSU00890" /db_xref="EnsemblGenomes-Tr:CAB11865" /db_xref="GOA:Q06754" /db_xref="InterPro:IPR002716" /db_xref="InterPro:IPR002792" /db_xref="InterPro:IPR029060" /db_xref="SubtiList:BG10151" /db_xref="UniProtKB/Swiss-Prot:Q06754" /translation="MLKRIVQAFFIIFGGVVGIFLIPELFVLLNIQDIPLITNAYTSA AIGAIIFFLISIWGTEYVVNWVKWIEDSLLKAPVPDLLFGSLGLVFGLIIAYLIVNVI PLDNIPYRIFSTIIPVFLAFFLGYLGFQVGFKKKDELISLFSISARMQKKKGTADEEH EVQDKKLKILDTSVIIDGRIADICQTGFLEGVIVIPQFVLEELQHIADSSDVLKRNRG RRGLDILNRIQKELDIEVEIYEGDFEDIQEVDSKLVKLAKLTSGVVVTNDFNLNKVCE LQKVAVLNINDLANAVKPVVLPGEEMNVQVIKDGKEHNQGVAYLDDGTMIVVEEGRNY IGKHIDVLVTSVLQTAAGRMIFAKPKLLEKAL*" gene 108674..109774 /gene="yacL" /locus_tag="BSU_00890" /old_locus_tag="BSU00890" downshifts complement(109596) /Source="Nicolas_upshifts" /id="D39" /incds=1 /nref=1 /ntot=103 /MaxReadThrough="0.39171" /MaxDrop="2.87304" /score="-9.71423487" /energy="-11.8" /TU="NA" /idTUdmin="U82" /TUdmin="-8228" /isTUend="FALSE" CDS 109789..110487 /gene="ispD" /locus_tag="BSU_00900" /old_locus_tag="BSU00900" /EC_number="2.7.7.60" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:12682299, 15044829, 15379557, 16533036, 17081012, 17458547, 23840410, 27821871" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12682299, 15044829, 15379557, 16533036, 17081012, 17458547, 23840410, 27821871; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, nonmevalonate isoprenoid pathway" /protein_id="NP_387971.1" /db_xref="EnsemblGenomes-Gn:BSU00900" /db_xref="EnsemblGenomes-Tr:CAB11866" /db_xref="GOA:Q06755" /db_xref="InterPro:IPR001228" /db_xref="InterPro:IPR018294" /db_xref="InterPro:IPR029044" /db_xref="InterPro:IPR034683" /db_xref="PDB:5DDT" /db_xref="PDB:5DDV" /db_xref="PDB:5HS2" /db_xref="SubtiList:BG10152" /db_xref="UniProtKB/Swiss-Prot:Q06755" /translation="MSYDVVIPAAGQGKRMKAGRNKLFIELKGDPVIIHTLRVFDSHR QCDKIILVINEQEREHFQQLLSDYPFQTSIELVAGGDERQHSVYKGLKAVKQEKIVLV HDGARPFIKHEQIDELIAEAEQTGAAILAVPVKDTIKRVQDLQVSETIERSSLWAVQT PQAFRLSLLMKAHAEAERKGFLGTDDASLVEQMEGGSVRVVEGSYTNIKLTTPDDLTS AEAIMESESGNKHV*" gene 109789..110487 /gene="ispD" /locus_tag="BSU_00900" /old_locus_tag="BSU00900" CDS 110480..110956 /gene="ispF" /locus_tag="BSU_00910" /old_locus_tag="BSU00910" /EC_number="4.6.1.12" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:9622350, 11997478, 12270818, 12682299, 17458547, 23840410" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9622350, 11997478, 12270818, 12682299, 17458547, 23840410; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase" /protein_id="NP_387972.1" /db_xref="EnsemblGenomes-Gn:BSU00910" /db_xref="EnsemblGenomes-Tr:CAB11867" /db_xref="GOA:Q06756" /db_xref="InterPro:IPR003526" /db_xref="InterPro:IPR020555" /db_xref="InterPro:IPR036571" /db_xref="PDB:5IWX" /db_xref="PDB:5IWY" /db_xref="SubtiList:BG10153" /db_xref="UniProtKB/Swiss-Prot:Q06756" /translation="MFRIGQGFDVHQLVEGRPLIIGGIEIPYEKGLLGHSDADVLLHT VADACLGAVGEGDIGKHFPDTDPEFKDADSFKLLQHVWGIVKQKGYVLGNIDCTIIAQ KPKMLPYIEDMRKRIAEGLEADVSQVNVKATTTEKLGFTGRAEGIAAQATVLIQKG*" gene 110480..110956 /gene="ispF" /locus_tag="BSU_00910" /old_locus_tag="BSU00910" promotor_-35 110960..110967 /Source="Nicolas_upshift_promotors" /id="U84" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.606393606393606" /psig="0.999000999001" /xcortree=2679 /SigmaFactorBS="cagtactgatacaaaaaggctaacttGTTTTGATgccgggtc tatttGGTGGTAGAATAGATTCATAcatttttgcctgaggccatacatgacatgaaag g" /listShort="gltX, S46, cysE, cysS, mrnC, rlmB, yacP, sigH, S47, rpmGB, secE, S48, nusG" /listLong="S49, rplK, S50, rplA, NA, rplJ, rplL, ybxB, S51, rpoB, rpoC, S52, rplGB, S53, rpsL, rpsG, fusA, S54, tufA, ybaC, S55, rpsJ, rplC, rplD, rplW, rplB, rpsS, rplV, rpsC, rplP, rpmC, rpsQ, rplNA, rplX, rplE, rpsNA, rpsH, rplF, rplR, rpsE, rpmD, rplO, secY, adk, mapA, ybzG, infA, rpmJ, rpsM, rpsK, S56, rpoA, rplQ, S57, ybxA, ybaE, ybaF, truA, NA, rplM, rpsI, S59, ybaJ" /label="promotor_-35" promotor_-10 110981..111000 /Source="Nicolas_upshift_promotors" /id="U84" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.606393606393606" /psig="0.999000999001" /xcortree=2679 /SigmaFactorBS="cagtactgatacaaaaaggctaacttGTTTTGATgccgggtc tatttGGTGGTAGAATAGATTCATAcatttttgcctgaggccatacatgacatgaaag g" /listShort="gltX, S46, cysE, cysS, mrnC, rlmB, yacP, sigH, S47, rpmGB, secE, S48, nusG" /listLong="S49, rplK, S50, rplA, NA, rplJ, rplL, ybxB, S51, rpoB, rpoC, S52, rplGB, S53, rpsL, rpsG, fusA, S54, tufA, ybaC, S55, rpsJ, rplC, rplD, rplW, rplB, rpsS, rplV, rpsC, rplP, rpmC, rpsQ, rplNA, rplX, rplE, rpsNA, rpsH, rplF, rplR, rpsE, rpmD, rplO, secY, adk, mapA, ybzG, infA, rpmJ, rpsM, rpsK, S56, rpoA, rplQ, S57, ybxA, ybaE, ybaF, truA, NA, rplM, rpsI, S59, ybaJ" /label="promotor_-10" upshifts 110994 /Source="Nicolas_upshifts" /id="U84" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.606393606393606" /psig="0.999000999001" /xcortree=2679 /SigmaFactorBS="cagtactgatacaaaaaggctaacttGTTTTGATgccgggtc tatttGGTGGTAGAATAGATTCATAcatttttgcctgaggccatacatgacatgaaag g" /listShort="gltX, S46, cysE, cysS, mrnC, rlmB, yacP, sigH, S47, rpmGB, secE, S48, nusG" /listLong="S49, rplK, S50, rplA, NA, rplJ, rplL, ybxB, S51, rpoB, rpoC, S52, rplGB, S53, rpsL, rpsG, fusA, S54, tufA, ybaC, S55, rpsJ, rplC, rplD, rplW, rplB, rpsS, rplV, rpsC, rplP, rpmC, rpsQ, rplNA, rplX, rplE, rpsNA, rpsH, rplF, rplR, rpsE, rpmD, rplO, secY, adk, mapA, ybzG, infA, rpmJ, rpsM, rpsK, S56, rpoA, rplQ, S57, ybxA, ybaE, ybaF, truA, NA, rplM, rpsI, S59, ybaJ" CDS 111047..112498 /gene="gltX" /locus_tag="BSU_00920" /old_locus_tag="BSU00920" /EC_number="6.1.1.24" /EC_number="6.1.1.17" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:2120226, 3079749, 9342321, 10024179, 10546897, 12682299, 14741355" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 2120226, 3079749, 9342321, 10024179, 10546897, 12682299, 14741355; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="glutamyl-tRNA synthetase" /protein_id="NP_387973.1" /db_xref="EnsemblGenomes-Gn:BSU00920" /db_xref="EnsemblGenomes-Tr:CAB11868" /db_xref="GOA:P22250" /db_xref="InterPro:IPR000924" /db_xref="InterPro:IPR001412" /db_xref="InterPro:IPR004527" /db_xref="InterPro:IPR008925" /db_xref="InterPro:IPR014729" /db_xref="InterPro:IPR020058" /db_xref="InterPro:IPR020061" /db_xref="InterPro:IPR020751" /db_xref="InterPro:IPR020752" /db_xref="InterPro:IPR033910" /db_xref="SubtiList:BG10154" /db_xref="UniProtKB/Swiss-Prot:P22250" /translation="MGNEVRVRYAPSPTGHLHIGNARTALFNYLFARNQGGKFIIRVE DTDKKRNIEGGEQSQLNYLKWLGIDWDESVDVGGEYGPYRQSERNDIYKVYYEELLEK GLAYKCYCTEEELEKEREEQIARGEMPRYSGKHRDLTQEEQEKFIAEGRKPSIRFRVP EGKVIAFNDIVKGEISFESDGIGDFVIVKKDGTPTYNFAVAIDDYLMKMTHVLRGEDH ISNTPKQIMIYQAFGWDIPQFGHMTLIVNESRKKLSKRDESIIQFIEQYKELGYLPEA LFNFIGLLGWSPVGEEELFTKEQFIEIFDVNRLSKSPALFDMHKLKWVNNQYVKKLDL DQVVELTLPHLQKAGKVGTELSAEEQEWVRKLISLYHEQLSYGAEIVELTDLFFTDEI EYNQEAKAVLEEEQVPEVLSTFAAKLEELEEFTPDNIKASIKAVQKETGHKGKKLFMP IRVAVTGQTHGPELPQSIELIGKETAIQRLKNI*" gene 111047..112498 /gene="gltX" /locus_tag="BSU_00920" /old_locus_tag="BSU00920" promotor_-35 111976..111985 /Source="Nicolas_upshift_promotors" /id="U85" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1307 /SigmaFactorBS="agcagtttattgaaatttttgatgtaaatcgtttatcTAAAT CACCAgctttgtttgataTGCATAAGCTAAAATGGGTTaacaaccaatatgtgaagaa g" /listShort="S46, cysE, cysS, mrnC, rlmB, yacP" /listLong="sigH, S47, rpmGB, secE, S48, nusG, S49, rplK, S50, rplA, NA, rplJ, rplL, ybxB, S51, rpoB, rpoC, S52, rplGB, S53, rpsL, rpsG, fusA, S54, tufA" /label="promotor_-35" promotor_-10 111999..112018 /Source="Nicolas_upshift_promotors" /id="U85" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1307 /SigmaFactorBS="agcagtttattgaaatttttgatgtaaatcgtttatcTAAAT CACCAgctttgtttgataTGCATAAGCTAAAATGGGTTaacaaccaatatgtgaagaa g" /listShort="S46, cysE, cysS, mrnC, rlmB, yacP" /listLong="sigH, S47, rpmGB, secE, S48, nusG, S49, rplK, S50, rplA, NA, rplJ, rplL, ybxB, S51, rpoB, rpoC, S52, rplGB, S53, rpsL, rpsG, fusA, S54, tufA" /label="promotor_-10" upshifts 111999 /Source="Nicolas_upshifts" /id="U85" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1307 /SigmaFactorBS="agcagtttattgaaatttttgatgtaaatcgtttatcTAAAT CACCAgctttgtttgataTGCATAAGCTAAAATGGGTTaacaaccaatatgtgaagaa g" /listShort="S46, cysE, cysS, mrnC, rlmB, yacP" /listLong="sigH, S47, rpmGB, secE, S48, nusG, S49, rplK, S50, rplA, NA, rplJ, rplL, ybxB, S51, rpoB, rpoC, S52, rplGB, S53, rpsL, rpsG, fusA, S54, tufA" S_feature 112499..112799 /Source="Nicolas_S_feature" /locus_tag="new_112499_112799" /HighExp="S6, S8, S7, Diami, C90, LBGexp, G135, H2O2, dia5, HiTm" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.17844199999999999" /TUshortSig="SigK, SigA, SigWXY" /TUshortPSig="1, 0.999, 1" /TUlongSig="SigA, SigB, SigA" /TUlongPSig="1, 1, 0.947" /label="S46" CDS 112800..113453 /gene="cysE" /locus_tag="BSU_00930" /old_locus_tag="BSU00930" /EC_number="2.3.1.30" /function="16.2: Construct biomass (Anabolism)" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:7510287, 10737181, 10939241, 17056751, 18974048, 25731080" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7510287, 10737181, 10939241, 17056751, 18974048, 25731080; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="serine O-acetyltransferase" /protein_id="NP_387974.1" /db_xref="EnsemblGenomes-Gn:BSU00930" /db_xref="EnsemblGenomes-Tr:CAB11869" /db_xref="GOA:Q06750" /db_xref="InterPro:IPR001451" /db_xref="InterPro:IPR005881" /db_xref="InterPro:IPR010493" /db_xref="InterPro:IPR011004" /db_xref="InterPro:IPR018357" /db_xref="SubtiList:BG10155" /db_xref="UniProtKB/Swiss-Prot:Q06750" /translation="MFFRMLKEDIDTVFDQDPAARSYFEVILTYSGLHAIWAHRIAHA LYKRKFYFLARLISQVSRFFTGIEIHPGATIGRRFFIDHGMGVVIGETCEIGNNVTVF QGVTLGGTGKEKGKRHPTIKDDALIATGAKVLGSITVGEGSKIGAGSVVLHDVPDFST VVGIPGRVVVQNGKKVRRDLNHQDLPDPVADRFKSLEQQILELKAELEDRKERINQK* " gene 112800..113453 /gene="cysE" /locus_tag="BSU_00930" /old_locus_tag="BSU00930" CDS 113450..114850 /gene="cysS" /locus_tag="BSU_00940" /old_locus_tag="BSU00940" /EC_number="6.1.1.16" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:10024179, 10546897, 10931887, 12682299, 29079736" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10024179, 10546897, 10931887, 12682299, 29079736; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="dual cysteinyl-tRNA synthetase; cysteine persulfide synthase" /protein_id="NP_387975.1" /db_xref="EnsemblGenomes-Gn:BSU00940" /db_xref="EnsemblGenomes-Tr:CAB11870" /db_xref="GOA:Q06752" /db_xref="InterPro:IPR009080" /db_xref="InterPro:IPR014729" /db_xref="InterPro:IPR015273" /db_xref="InterPro:IPR015803" /db_xref="InterPro:IPR024909" /db_xref="InterPro:IPR032678" /db_xref="SubtiList:BG10156" /db_xref="UniProtKB/Swiss-Prot:Q06752" /translation="MTITLYNTLTRQKETFVPLEEGKVKMYVCGPTVYNYIHIGNARP AIVYDTVRNYLEYKGYDVQYVSNFTDVDDKLIKAANELGEDVPTISERFIKAYFEDVG ALGCRKADLHPRVMENMDAIIEFVDQLVKKGYAYESEGDVYFKTRAFEGYGKLSQQSI DELRSGARIRVGEKKEDALDFALWKAAKEGEISWDSPWGKGRPGWHIECSAMVKKYLG DQIDIHAGGQDLTFPHHENEIAQSEALTGKTFAKYWLHNGYINIDNEKMSKSLGNFVL VHDIIKQHDPQLLRFFMLSVHYRHPINYSEELLENTKSAFSRLKTAYSNLQHRLNSST NLTEDDDQWLEKVEEHRKAFEEEMDDDFNTANAISVLFDLAKHANYYLQKDHTADHVI TAFIEMFDRIVSVLGFSLGEQELLDQEIEDLIEKRNEARRNRDFALSDQIRDQLKSMN IILEDTAQGTRWKRGE*" gene 113450..114850 /gene="cysS" /locus_tag="BSU_00940" /old_locus_tag="BSU00940" CDS 114854..115285 /gene="mrnC" /locus_tag="BSU_00950" /old_locus_tag="BSU00950" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:16014871, 25634891, 27924926" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16014871, 25634891, 27924926; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="ribonuclease for 23S RNA maturation, mini-RNase III" /protein_id="NP_387976.1" /db_xref="EnsemblGenomes-Gn:BSU00950" /db_xref="EnsemblGenomes-Tr:CAB11871" /db_xref="GOA:O31418" /db_xref="InterPro:IPR000999" /db_xref="InterPro:IPR008226" /db_xref="InterPro:IPR036389" /db_xref="PDB:4OUN" /db_xref="SubtiList:BG12702" /db_xref="UniProtKB/Swiss-Prot:O31418" /translation="MLEFDTIKDSKQLNGLALAYIGDAIFEVYVRHHLLKQGFTKPND LHKKSSRIVSAKSQAEILFFLQNQSFFTEEEEAVLKRGRNAKSGTTPKNTDVQTYRYS TAFEALLGYLFLEKKEERLSQLVAEAIQFGTSGRKTNESAT*" gene 114854..115285 /gene="mrnC" /locus_tag="BSU_00950" /old_locus_tag="BSU00950" CDS 115269..116018 /gene="rlmB" /locus_tag="BSU_00960" /old_locus_tag="BSU00960" /EC_number="2.1.1.185" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 11698387, 12377117, 16014871; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="23S rRNA (Gm2251)-methyltransferase" /protein_id="NP_387977.1" /db_xref="EnsemblGenomes-Gn:BSU00960" /db_xref="EnsemblGenomes-Tr:CAB11872" /db_xref="GOA:Q06753" /db_xref="InterPro:IPR001537" /db_xref="InterPro:IPR004441" /db_xref="InterPro:IPR013123" /db_xref="InterPro:IPR029026" /db_xref="InterPro:IPR029028" /db_xref="InterPro:IPR029064" /db_xref="SubtiList:BG10157" /db_xref="UniProtKB/Swiss-Prot:Q06753" /translation="MSQQHDYVIGKNAVIETLKSDRKLYKLWMAENTVKGQAQQVIEL AKKQGITIQYVPRKKLDQMVTGQHQGVVAQVAAYEYAELDDLYKAAEEKNEQPFFLIL DELEDPHNLGSIMRTADAVGAHGIVIPKRRAVGLTTTVAKASTGAIEHIPVARVTNLA RTLEEMKERGIWVVGTDASAREDFRNMDGNMPLALVIGSEGKGMGRLVKEKCDFLIKL PMAGKVTSLNASVAAGLLMYEVYRKRNPVGE*" gene 115269..116018 /gene="rlmB" /locus_tag="BSU_00960" /old_locus_tag="BSU00960" CDS 116025..116537 /gene="raeA" /locus_tag="BSU_00970" /old_locus_tag="BSU00970" /function="16.11: Scavenge (Catabolism)" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:17114934, 23355615, 28363943" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 17114934, 23355615, 28363943; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="ribosome-dependent mRNA endonuclease" /protein_id="NP_387978.1" /db_xref="EnsemblGenomes-Gn:BSU00970" /db_xref="EnsemblGenomes-Tr:CAB11873" /db_xref="InterPro:IPR010298" /db_xref="PDB:5MQ8" /db_xref="PDB:5MQ9" /db_xref="SubtiList:BG10158" /db_xref="UniProtKB/Swiss-Prot:P37574" /translation="MDILLVDGYNMIGAWPQLKDLKANSFEEARDVLIQKMAEYQSYT GNRVIVVFDAHLVKGLEKKQTNHRVEVIFTKENETADERIEKLAQALNNIATQIHVAT SDYTEQWAIFGQGALRKSARELLREVETIERRIERRVRKITSEKPAGKIALSEEVLKT FEKWRRGDLD*" gene 116025..116537 /gene="raeA" /locus_tag="BSU_00970" /old_locus_tag="BSU00970" promotor_-35 116536..116543 /Source="Nicolas_upshift_promotors" /id="U86" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.71028971028971" /psig=1 /xcortree=3212 /SigmaFactorBS="aaacgtttgaaaagtggaggcggggagacttagattAAGTTG ACgcttttttgcccaaTACTGTATAATATTTCTATCtacgtgcgccggggggatcgga g" /listShort="sigH, S47, rpmGB, secE, S48, nusG" /listLong="S49, rplK, S50, rplA, NA, rplJ, rplL, ybxB, S51, rpoB, rpoC, S52, rplGB, S53, rpsL, rpsG, fusA, S54, tufA, ybaC, S55, rpsJ, rplC, rplD, rplW, rplB, rpsS, rplV, rpsC, rplP, rpmC, rpsQ, rplNA, rplX, rplE, rpsNA, rpsH, rplF, rplR, rpsE, rpmD, rplO, secY, adk, mapA, ybzG, infA, rpmJ, rpsM, rpsK, S56, rpoA, rplQ, S57, ybxA, ybaE, ybaF, truA, NA, rplM, rpsI, S59, ybaJ" /label="promotor_-35" promotor_-10 116558..116577 /Source="Nicolas_upshift_promotors" /id="U86" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.71028971028971" /psig=1 /xcortree=3212 /SigmaFactorBS="aaacgtttgaaaagtggaggcggggagacttagattAAGTTG ACgcttttttgcccaaTACTGTATAATATTTCTATCtacgtgcgccggggggatcgga g" /listShort="sigH, S47, rpmGB, secE, S48, nusG" /listLong="S49, rplK, S50, rplA, NA, rplJ, rplL, ybxB, S51, rpoB, rpoC, S52, rplGB, S53, rpsL, rpsG, fusA, S54, tufA, ybaC, S55, rpsJ, rplC, rplD, rplW, rplB, rpsS, rplV, rpsC, rplP, rpmC, rpsQ, rplNA, rplX, rplE, rpsNA, rpsH, rplF, rplR, rpsE, rpmD, rplO, secY, adk, mapA, ybzG, infA, rpmJ, rpsM, rpsK, S56, rpoA, rplQ, S57, ybxA, ybaE, ybaF, truA, NA, rplM, rpsI, S59, ybaJ" /label="promotor_-10" upshifts 116560 /Source="Nicolas_upshifts" /id="U86" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.71028971028971" /psig=1 /xcortree=3212 /SigmaFactorBS="aaacgtttgaaaagtggaggcggggagacttagattAAGTTG ACgcttttttgcccaaTACTGTATAATATTTCTATCtacgtgcgccggggggatcgga g" /listShort="sigH, S47, rpmGB, secE, S48, nusG" /listLong="S49, rplK, S50, rplA, NA, rplJ, rplL, ybxB, S51, rpoB, rpoC, S52, rplGB, S53, rpsL, rpsG, fusA, S54, tufA, ybaC, S55, rpsJ, rplC, rplD, rplW, rplB, rpsS, rplV, rpsC, rplP, rpmC, rpsQ, rplNA, rplX, rplE, rpsNA, rpsH, rplF, rplR, rpsE, rpmD, rplO, secY, adk, mapA, ybzG, infA, rpmJ, rpsM, rpsK, S56, rpoA, rplQ, S57, ybxA, ybaE, ybaF, truA, NA, rplM, rpsI, S59, ybaJ" CDS 116600..117256 /gene="sigH" /locus_tag="BSU_00980" /old_locus_tag="BSU00980" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:12169614, 16339734, 25288929, 26712348" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12169614, 16339734, 25288929, 26712348; Product type f: factor" /codon_start=1 /transl_table=11 /product="RNA polymerase sigma-30 factor (sigma(H))" /protein_id="NP_387979.1" /db_xref="EnsemblGenomes-Gn:BSU00980" /db_xref="EnsemblGenomes-Tr:CAB11874" /db_xref="GOA:P17869" /db_xref="InterPro:IPR000792" /db_xref="InterPro:IPR000943" /db_xref="InterPro:IPR007627" /db_xref="InterPro:IPR013249" /db_xref="InterPro:IPR013324" /db_xref="InterPro:IPR013325" /db_xref="InterPro:IPR014218" /db_xref="InterPro:IPR014284" /db_xref="InterPro:IPR016371" /db_xref="InterPro:IPR036388" /db_xref="SubtiList:BG10159" /db_xref="UniProtKB/Swiss-Prot:P17869" /translation="MNLQNNKGKFNKEQFCQLEDEQVIEKVHVGDSDALDYLITKYRN FVRAKARSYFLIGADREDIVQEGMIGLYKSIRDFKEDKLTSFKAFAELCITRQIITAI KTATRQKHIPLNSYASLDKPIFDEESDRTLLDVISGAKTLNPEEMIINQEEFDDIEMK MGELLSDLERKVLVLYLDGRSYQEISDELNRHVKSIDNALQRVKRKLEKYLEIREISL *" gene 116600..117256 /gene="sigH" /locus_tag="BSU_00980" /old_locus_tag="BSU00980" downshifts complement(117054) /Source="Nicolas_upshifts" /id="D40" /incds=1 /nref=1 /ntot=107 /MaxReadThrough="2.38622" /MaxDrop="2.50464" /score="-2.56993398" /energy="-10.3" /TU="NA" /idTUdmin="U87" /TUdmin=836 /isTUend="FALSE" S_feature 117257..117348 /Source="Nicolas_S_feature" /locus_tag="new_117257_117348" /HighExp="T4.0H, T3.30H, T3.0H, T2.30H, S1, S2, T5.0H, HiOs, T2.0H, T1.30H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="1, 0.999" /TUlongSig="SigK, SigWXY, SigA, SigB, SigA" /TUlongPSig="1, 1, 1, 1, 0.947" /label="S47" CDS 117349..117498 /gene="rpmGB" /locus_tag="BSU_00990" /old_locus_tag="BSU00990" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:12682299, 14586115, 19648245, 23002217, 27561249" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12682299, 14586115, 19648245, 23002217, 27561249; Product type f: factor" /codon_start=1 /transl_table=11 /product="ribosomal protein L33" /protein_id="NP_387980.1" /db_xref="EnsemblGenomes-Gn:BSU00990" /db_xref="EnsemblGenomes-Tr:CAB11875" /db_xref="GOA:Q06798" /db_xref="InterPro:IPR001705" /db_xref="InterPro:IPR011332" /db_xref="InterPro:IPR018264" /db_xref="SubtiList:BG10160" /db_xref="UniProtKB/Swiss-Prot:Q06798" /translation="MRKKITLACKTCGNRNYTTMKSSASAAERLEVKKYCSTCNSHTA HLETK*" gene 117349..117498 /gene="rpmGB" /locus_tag="BSU_00990" /old_locus_tag="BSU00990" CDS 117532..117711 /gene="secE" /locus_tag="BSU_01000" /old_locus_tag="BSU01000" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:11976315, 12682299, 16242710, 22304380, 22720735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11976315, 12682299, 16242710, 22304380, 22720735; Product type t : transporter" /codon_start=1 /transl_table=11 /product="preprotein translocase subunit" /protein_id="NP_387981.1" /db_xref="EnsemblGenomes-Gn:BSU01000" /db_xref="EnsemblGenomes-Tr:CAB11876" /db_xref="GOA:Q06799" /db_xref="InterPro:IPR001901" /db_xref="InterPro:IPR005807" /db_xref="InterPro:IPR022943" /db_xref="SubtiList:BG10161" /db_xref="UniProtKB/Swiss-Prot:Q06799" /translation="MRIMKFFKDVGKEMKKVSWPKGKELTRYTITVISTVIFFVIFFA LLDTGISQLIRLIVE*" gene 117532..117711 /gene="secE" /locus_tag="BSU_01000" /old_locus_tag="BSU01000" S_feature 117712..117889 /Source="Nicolas_S_feature" /locus_tag="new_117712_117889" /HighExp="Cold, G180, G150, H2O2, LoTm, Oxctl, G135, Paraq, LBGexp, Lbexp" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="1, 0.999" /TUlongSig="SigK, SigWXY, SigA, SigB, SigA" /TUlongPSig="1, 1, 1, 1, 0.947" /label="S48" downshifts complement(117883) /Source="Nicolas_upshifts" /id="D41" /incds=0 /nref=37 /ntot=175 /MaxReadThrough="1.57397" /MaxDrop="4.03552" /score="-2.56993398" /energy="-10.3" /TU="NA" /idTUdmin="U87" /TUdmin=7 /isTUend="TRUE" CDS 117890..118423 /gene="nusG" /locus_tag="BSU_01010" /old_locus_tag="BSU01010" /function="16.3: Control" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:11101662, 16014871, 16707701, 18852477, 26742846, 28507243" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11101662, 16014871, 16707701, 18852477, 26742846, 28507243; Product type f : factor" /codon_start=1 /transl_table=11 /product="RNA polymerase elongation pause factor" /protein_id="NP_387982.1" /db_xref="EnsemblGenomes-Gn:BSU01010" /db_xref="EnsemblGenomes-Tr:CAB11877" /db_xref="GOA:Q06795" /db_xref="InterPro:IPR001062" /db_xref="InterPro:IPR005824" /db_xref="InterPro:IPR006645" /db_xref="InterPro:IPR008991" /db_xref="InterPro:IPR014722" /db_xref="InterPro:IPR015869" /db_xref="InterPro:IPR036735" /db_xref="SubtiList:BG10162" /db_xref="UniProtKB/Swiss-Prot:Q06795" /translation="MEKNWYVVHTYSGYENKVKANLEKRVESMGMQDKIFRVVVPEEE ETDIKNGKKKVVKKKVFPGYVLVEIVMTDDSWYVVRNTPGVTGFVGSAGSGSKPTPLL PGEAETILKRMGMDERKTDIDFELKETVKVIDGPFANFTGSIEEIDYDKSKVKVFVNM FGRETPVELEFTQIDKL*" gene 117890..118423 /gene="nusG" /locus_tag="BSU_01010" /old_locus_tag="BSU01010" upshifts complement(117978) /Source="Nicolas_upshifts" /id="U87" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.98001998001998" /psig="0.002997002997003" /xcortree=29 /SigmaFactorBS="tttttgatatccgtttcttcttcttcgggtacgACTACAcgg aaaattttatcCTGCAtccccattgattcaacacgcttttccaagttggcttttactt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 complement(117981..117985) /Source="Nicolas_upshift_promotors" /id="U87" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.98001998001998" /psig="0.002997002997003" /xcortree=29 /SigmaFactorBS="tttttgatatccgtttcttcttcttcgggtacgACTACAcgg aaaattttatcCTGCAtccccattgattcaacacgcttttccaagttggcttttactt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 complement(118000..118005) /Source="Nicolas_upshift_promotors" /id="U87" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.98001998001998" /psig="0.002997002997003" /xcortree=29 /SigmaFactorBS="tttttgatatccgtttcttcttcttcgggtacgACTACAcgg aaaattttatcCTGCAtccccattgattcaacacgcttttccaagttggcttttactt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 118434..118441 /Source="Nicolas_upshift_promotors" /id="U88" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.787212787212787" /psig=1 /xcortree=2652 /SigmaFactorBS="agctggaatttacccaaatcgataaattgtaatgtgaaaaaa CTTGAAATtgctatatataaaTGATAATATAGCAAAGGTACgtcttggacttatccaa g" /listShort="S49, rplK, S50, rplA, NA, rplJ, rplL, ybxB, S51, rpoB, rpoC, S52, rplGB, S53, rpsL, rpsG, fusA, S54, tufA, ybaC" /listLong="S55, rpsJ, rplC, rplD, rplW, rplB, rpsS, rplV, rpsC, rplP, rpmC, rpsQ, rplNA, rplX, rplE, rpsNA, rpsH, rplF, rplR, rpsE, rpmD, rplO, secY, adk, mapA, ybzG, infA, rpmJ, rpsM, rpsK, S56, rpoA, rplQ, S57, ybxA, ybaE, ybaF, truA, NA, rplM, rpsI, S59, ybaJ" /label="promotor_-35" S_feature 118452..118590 /Source="Nicolas_S_feature" /locus_tag="new_118452_118590" /HighExp="T-1.40H, ferm, T-3.40H, T-5.40H, BI, B36, LoTm, SMM, T-2.40H, nit" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="SigA, SigK, SigA, SigWXY, SigA, SigB, SigA" /TUlongPSig="1, 1, 0.999, 1, 1, 1, 0.947" /label="S49" upshifts 118452 /Source="Nicolas_upshifts" /id="U88" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.787212787212787" /psig=1 /xcortree=2652 /SigmaFactorBS="agctggaatttacccaaatcgataaattgtaatgtgaaaaaa CTTGAAATtgctatatataaaTGATAATATAGCAAAGGTACgtcttggacttatccaa g" /listShort="S49, rplK, S50, rplA, NA, rplJ, rplL, ybxB, S51, rpoB, rpoC, S52, rplGB, S53, rpsL, rpsG, fusA, S54, tufA, ybaC" /listLong="S55, rpsJ, rplC, rplD, rplW, rplB, rpsS, rplV, rpsC, rplP, rpmC, rpsQ, rplNA, rplX, rplE, rpsNA, rpsH, rplF, rplR, rpsE, rpmD, rplO, secY, adk, mapA, ybzG, infA, rpmJ, rpsM, rpsK, S56, rpoA, rplQ, S57, ybxA, ybaE, ybaF, truA, NA, rplM, rpsI, S59, ybaJ" promotor_-10 118455..118474 /Source="Nicolas_upshift_promotors" /id="U88" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.787212787212787" /psig=1 /xcortree=2652 /SigmaFactorBS="agctggaatttacccaaatcgataaattgtaatgtgaaaaaa CTTGAAATtgctatatataaaTGATAATATAGCAAAGGTACgtcttggacttatccaa g" /listShort="S49, rplK, S50, rplA, NA, rplJ, rplL, ybxB, S51, rpoB, rpoC, S52, rplGB, S53, rpsL, rpsG, fusA, S54, tufA, ybaC" /listLong="S55, rpsJ, rplC, rplD, rplW, rplB, rpsS, rplV, rpsC, rplP, rpmC, rpsQ, rplNA, rplX, rplE, rpsNA, rpsH, rplF, rplR, rpsE, rpmD, rplO, secY, adk, mapA, ybzG, infA, rpmJ, rpsM, rpsK, S56, rpoA, rplQ, S57, ybxA, ybaE, ybaF, truA, NA, rplM, rpsI, S59, ybaJ" /label="promotor_-10" CDS 118591..119016 /gene="rplK" /locus_tag="BSU_01020" /old_locus_tag="BSU01020" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:11244072, 19653700, 20441189" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11244072, 19653700, 20441189; Product type s: structure" /codon_start=1 /transl_table=11 /product="ribosomal protein L11 (BL11)" /protein_id="NP_387983.2" /db_xref="EnsemblGenomes-Gn:BSU01020" /db_xref="EnsemblGenomes-Tr:CAB11878" /db_xref="GOA:Q06796" /db_xref="InterPro:IPR000911" /db_xref="InterPro:IPR006519" /db_xref="InterPro:IPR020783" /db_xref="InterPro:IPR020784" /db_xref="InterPro:IPR020785" /db_xref="InterPro:IPR036769" /db_xref="InterPro:IPR036796" /db_xref="PDB:3J3V" /db_xref="PDB:3J3W" /db_xref="PDB:3J9W" /db_xref="SubtiList:BG10163" /db_xref="UniProtKB/Swiss-Prot:Q06796" /translation="MAKKVVKVVKLQIPAGKANPAPPVGPALGQAGVNIMGFCKEFNA RTADQAGLIIPVEISVYEDRSFTFITKTPPAAVLLKKAAGIESGSGEPNRNKVATVKR DKVREIAETKMPDLNAADVEAAMRMVEGTARSMGIVIED*" gene 118591..119016 /gene="rplK" /locus_tag="BSU_01020" /old_locus_tag="BSU01020" S_feature 119017..119110 /Source="Nicolas_S_feature" /locus_tag="new_119017_119110" /HighExp="HPh, LPh, Lbexp, G180, LBGexp, G150, Heat, Cold, Fru, Oxctl" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="SigA, SigK, SigA, SigWXY, SigA, SigB, SigA" /TUlongPSig="1, 1, 0.999, 1, 1, 1, 0.947" /label="S50" CDS 119111..119809 /gene="rplA" /locus_tag="BSU_01030" /old_locus_tag="BSU01030" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 12682299, 16352840, 17981968, 22720735; Product type s: structure" /codon_start=1 /transl_table=11 /product="ribosomal protein L1 (BL1)" /protein_id="NP_387984.2" /db_xref="EnsemblGenomes-Gn:BSU01030" /db_xref="EnsemblGenomes-Tr:CAB11879" /db_xref="GOA:Q06797" /db_xref="InterPro:IPR002143" /db_xref="InterPro:IPR005878" /db_xref="InterPro:IPR016095" /db_xref="InterPro:IPR023673" /db_xref="InterPro:IPR023674" /db_xref="InterPro:IPR028364" /db_xref="PDB:3J3V" /db_xref="PDB:3J3W" /db_xref="SubtiList:BG10164" /db_xref="UniProtKB/Swiss-Prot:Q06797" /translation="MAKKGKKYVEAAKLVDRSKAYDVSEAVALVKKTNTAKFDATVEV AFRLGVDPRKNDQQIRGAVVLPNGTGKTQRVLVFAKGEKAKEAEAAGADFVGDTDYIN KIQQGWFDFDVIVATPDMMGEVGKIGRVLGPKGLMPNPKTGTVTFEVEKAIGEIKAGK VEYRVDKAGNIHVPIGKVSFEDEKLVENFTTMYDTILKAKPAAAKGVYVKNVAVTSTM GPGVKVDSSTFNVK*" gene 119111..119809 /gene="rplA" /locus_tag="BSU_01030" /old_locus_tag="BSU01030" downshifts complement(119783) /Source="Nicolas_upshifts" /id="D42" /incds=0 /nref=3 /ntot=95 /MaxReadThrough="3.54108" /MaxDrop="3.36566" /score="-2.56993398" /energy="-10.3" /TU="NA" /idTUdmin="U89" /TUdmin=0 /isTUend="TRUE" misc_RNA 119855..119995 /gene="ldlJ" /locus_tag="BSU_misc_RNA_3" /product="L10_leader" /experiment="publication(s) with functional evidences, PMID:26101249" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 26101249; Product type n: RNA" gene 119855..119995 /gene="ldlJ" /locus_tag="BSU_misc_RNA_3" upshifts complement(119871) /Source="Nicolas_upshifts" /id="U89" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.603396603396603" /psig="0.248751248751249" /xcortree=60 /SigmaFactorBS="gctgtgataatatacacctcggtaggataattaagcggttag gcccctactgtCTACGgtataaatgatattctattttacaacattttgaataatatca g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" misc_feature complement(119874..119878) /Source="Nicolas_upshift_promotors" /id="U89" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.603396603396603" /psig="0.248751248751249" /xcortree=60 /SigmaFactorBS="gctgtgataatatacacctcggtaggataattaagcggttag gcccctactgtCTACGgtataaatgatattctattttacaacattttgaataatatca g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" downshifts 119927 /Source="Nicolas_upshifts" /id="D43" /incds=1 /nref=1 /ntot=19 /MaxReadThrough="9.14839" /MaxDrop="2.9211" /score="20.0562348" /energy="-13.2" /TU="U88" /idTUdmin="U84" /TUdmin=1497 /isTUend="FALSE" CDS 120061..120561 /gene="rplJ" /locus_tag="BSU_01040" /old_locus_tag="BSU01040" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:9810686, 11341315, 12682299, 18247578, 26101249, 22720735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9810686, 11341315, 12682299, 18247578, 26101249, 22720735; Product type s : structure" /codon_start=1 /transl_table=11 /product="ribosomal protein L10 (BL5)" /protein_id="NP_387985.2" /db_xref="EnsemblGenomes-Gn:BSU01040" /db_xref="EnsemblGenomes-Tr:CAB11880" /db_xref="GOA:P42923" /db_xref="InterPro:IPR001790" /db_xref="InterPro:IPR002363" /db_xref="InterPro:IPR022973" /db_xref="PDB:3J9W" /db_xref="PDB:5NJT" /db_xref="SubtiList:BG11220" /db_xref="UniProtKB/Swiss-Prot:P42923" /translation="MSSAIETKKVVVEEIASKLKESKSTIIVDYRGLNVSEVTELRKQ LREANVEFKVYKNTMTRRAVEQAELNGLNDFLTGPNAIAFSTEDVVAPAKVLNDFAKN HEALEIKAGVIEGKVSTVEEVKALAELPSREGLLSMLLSVLQAPVRNLALAAKAVAEQ KEEQGA*" gene 120061..120561 /gene="rplJ" /locus_tag="BSU_01040" /old_locus_tag="BSU01040" CDS 120607..120978 /gene="rplL" /locus_tag="BSU_01050" /old_locus_tag="BSU01050" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:12682299, 6771249, 8755892, 26101249" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12682299, 6771249, 8755892, 26101249; Product type s: structure" /codon_start=1 /transl_table=11 /product="ribosomal protein L12 (BL9)" /protein_id="NP_387986.1" /db_xref="EnsemblGenomes-Gn:BSU01050" /db_xref="EnsemblGenomes-Tr:CAB11881" /db_xref="GOA:P02394" /db_xref="InterPro:IPR000206" /db_xref="InterPro:IPR008932" /db_xref="InterPro:IPR013823" /db_xref="InterPro:IPR014719" /db_xref="InterPro:IPR036235" /db_xref="SubtiList:BG10726" /db_xref="UniProtKB/Swiss-Prot:P02394" /translation="MALNIEEIIASVKEATVLELNDLVKAIEEEFGVTAAAPVAVAGG AAAGGAAEEQSEFDLILAGAGSQKIKVIKVVREITGLGLKEAKELVDNTPKPLKEGIA KEEAEELKAKLEEVGASVEVK*" gene 120607..120978 /gene="rplL" /locus_tag="BSU_01050" /old_locus_tag="BSU01050" downshifts 120894 /Source="Nicolas_upshifts" /id="D44" /incds=1 /nref=5 /ntot=149 /MaxReadThrough="8.89506" /MaxDrop="4.0945" /score="20.6066659" /energy="-11.7" /TU="U88" /idTUdmin="U84" /TUdmin=2464 /isTUend="FALSE" downshifts 120967 /Source="Nicolas_upshifts" /id="D45" /incds=0 /nref=25 /ntot=157 /MaxReadThrough="7.44654" /MaxDrop="4.0033" /score="20.6066659" /energy="-11.7" /TU="U88" /idTUdmin="U84" /TUdmin=2537 /isTUend="FALSE" CDS 121068..121673 /gene="rlmG" /locus_tag="BSU_01060" /old_locus_tag="BSU01060" /EC_number="2.1.1.174" /function="16.6: Maintain" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 17010380; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="23S rRNA m2G1835 methyltransferase" /protein_id="NP_387987.1" /db_xref="EnsemblGenomes-Gn:BSU01060" /db_xref="EnsemblGenomes-Tr:CAB11882" /db_xref="GOA:P37872" /db_xref="InterPro:IPR007848" /db_xref="InterPro:IPR029063" /db_xref="SubtiList:BG10727" /db_xref="UniProtKB/Swiss-Prot:P37872" /translation="MSEHYYSEKPSVKSNKQTWSFRLRNKDFTFTSDSGVFSKKEVDF GSRLLIDSFEEPEVEGGILDVGCGYGPIGLSLASDFKDRTIHMIDVNERAVELSNENA EQNGITNVKIYQSDLFSNVDSAQTFASILTNPPIRAGKKVVHAIFEKSAEHLKASGEL WIVIQKKQGAPSAIEKLEELFDEVSVVQKKKGYYIIKAKKV*" gene 121068..121673 /gene="rlmG" /locus_tag="BSU_01060" /old_locus_tag="BSU01060" promotor_-35 121668..121672 /Source="Nicolas_upshift_promotors" /id="U90" /multdbtbs="SigA" /comp="M16" /sig="SigA" /pcomp="0.586413586413586" /psig="0.997002997002997" /xcortree=2493 /SigmaFactorBS="gttcaaaaaaagaaaggctattatatcataaaagcaaaaaaa GTTTGactcggtattttaacTATGTTAATATTGTAAAATGccaatgtatatattttgc t" /listShort="S51, rpoB, rpoC, S52, rplGB, S53, rpsL, rpsG, fusA, S54, tufA, ybaC" /listLong="S55, rpsJ, rplC, rplD, rplW, rplB, rpsS, rplV, rpsC, rplP, rpmC, rpsQ, rplNA, rplX, rplE, rpsNA, rpsH, rplF, rplR, rpsE, rpmD, rplO, secY, adk, mapA, ybzG, infA, rpmJ, rpsM, rpsK, S56, rpoA, rplQ, S57, ybxA, ybaE, ybaF, truA, NA, rplM, rpsI, S59, ybaJ" /label="promotor_-35" S_feature 121686..121918 /Source="Nicolas_S_feature" /locus_tag="new_121686_121918" /HighExp="G180, G150, H2O2, G135, Cold, T-5.40H, LoTm, T-3.40H, Oxctl, Salt" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="0.997, 1" /TUlongSig="SigA, SigK, SigA, SigWXY, SigA, SigB, SigA" /TUlongPSig="1, 1, 0.999, 1, 1, 1, 0.947" /label="S51" upshifts 121686 /Source="Nicolas_upshifts" /id="U90" /multdbtbs="SigA" /comp="M16" /sig="SigA" /pcomp="0.586413586413586" /psig="0.997002997002997" /xcortree=2493 /SigmaFactorBS="gttcaaaaaaagaaaggctattatatcataaaagcaaaaaaa GTTTGactcggtattttaacTATGTTAATATTGTAAAATGccaatgtatatattttgc t" /listShort="S51, rpoB, rpoC, S52, rplGB, S53, rpsL, rpsG, fusA, S54, tufA, ybaC" /listLong="S55, rpsJ, rplC, rplD, rplW, rplB, rpsS, rplV, rpsC, rplP, rpmC, rpsQ, rplNA, rplX, rplE, rpsNA, rpsH, rplF, rplR, rpsE, rpmD, rplO, secY, adk, mapA, ybzG, infA, rpmJ, rpsM, rpsK, S56, rpoA, rplQ, S57, ybxA, ybaE, ybaF, truA, NA, rplM, rpsI, S59, ybaJ" promotor_-10 121688..121707 /Source="Nicolas_upshift_promotors" /id="U90" /multdbtbs="SigA" /comp="M16" /sig="SigA" /pcomp="0.586413586413586" /psig="0.997002997002997" /xcortree=2493 /SigmaFactorBS="gttcaaaaaaagaaaggctattatatcataaaagcaaaaaaa GTTTGactcggtattttaacTATGTTAATATTGTAAAATGccaatgtatatattttgc t" /listShort="S51, rpoB, rpoC, S52, rplGB, S53, rpsL, rpsG, fusA, S54, tufA, ybaC" /listLong="S55, rpsJ, rplC, rplD, rplW, rplB, rpsS, rplV, rpsC, rplP, rpmC, rpsQ, rplNA, rplX, rplE, rpsNA, rpsH, rplF, rplR, rpsE, rpmD, rplO, secY, adk, mapA, ybzG, infA, rpmJ, rpsM, rpsK, S56, rpoA, rplQ, S57, ybxA, ybaE, ybaF, truA, NA, rplM, rpsI, S59, ybaJ" /label="promotor_-10" CDS 121919..125500 /gene="rpoB" /locus_tag="BSU_01070" /old_locus_tag="BSU01070" /EC_number="2.7.7.6" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:10049799, 10744988, 12455702, 12682299, 15060052, 28163698" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10049799, 10744988, 12455702, 12682299, 15060052, 28163698; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="RNA polymerase (beta subunit)" /protein_id="NP_387988.2" /db_xref="EnsemblGenomes-Gn:BSU01070" /db_xref="EnsemblGenomes-Tr:CAB11883" /db_xref="GOA:P37870" /db_xref="InterPro:IPR007120" /db_xref="InterPro:IPR007121" /db_xref="InterPro:IPR007641" /db_xref="InterPro:IPR007642" /db_xref="InterPro:IPR007644" /db_xref="InterPro:IPR007645" /db_xref="InterPro:IPR010243" /db_xref="InterPro:IPR015712" /db_xref="InterPro:IPR019462" /db_xref="PDB:2LY7" /db_xref="SubtiList:BG10728" /db_xref="UniProtKB/Swiss-Prot:P37870" /translation="MTGQLVQYGRHRQRRSYARISEVLELPNLIEIQTSSYQWFLDEG LREMFQDISPIEDFTGNLSLEFIDYSLGEPKYPVEESKERDVTYSAPLRVKVRLINKE TGEVKDQDVFMGDFPIMTDTGTFIINGAERVIVSQLVRSPSVYFSGKVDKNGKKGFTA TVIPNRGAWLEYETDAKDVVYVRIDRTRKLPVTVLLRALGFGSDQEILDLIGENEYLR NTLDKDNTENSDKALLEIYERLRPGEPPTVENAKSLLDSRFFDPKRYDLANVGRYKIN KKLHIKNRLFNQRLAETLVDPETGEILAEKGQILDRRTLDKVLPYLENGIGFRKLYPN GGVVEDEVTLQSIKIFAPTDQEGEQVINVIGNAYIEEEIKNITPADIISSISYFFNLL HGVGDTDDIDHLGNRRLRSVGELLQNQFRIGLSRMERVVRERMSIQDTNTITPQQLIN IRPVIASIKEFFGSSQLSQFMDQTNPLAELTHKRRLSALGPGGLTRERAGMEVRDVHY SHYGRMCPIETPEGPNIGLINSLSSYAKVNRFGFIETPYRRVDPETGKVTGRIDYLTA DEEDNYVVAQANARLDDEGAFIDDSIVARFRGENTVVSRNRVDYMDVSPKQVVSAATA CIPFLENDDSNRALMGANMQRQAVPLMQPEAPFVGTGMEYVSGKDSGAAVICKHPGIV ERVEAKNVWVRRYEEVDGQKVKGNLDKYSLLKFVRSNQGTCYNQRPIVSVGDEVVKGE ILADGPSMELGELALGRNVMVGFMTWDGYNYEDAIIMSERLVKDDVYTSIHIEEYESE ARDTKLGPEEITRDIPNVGEDALRNLDDRGIIRIGAEVKDGDLLVGKVTPKGVTELTA EERLLHAIFGEKAREVRDTSLRVPHGGGGIIHDVKVFNREDGDELPPGVNQLVRVYIV QKRKISEGDKMAGRHGNKGVISKILPEEDMPYLPDGTPIDIMLNPLGVPSRMNIGQVL ELHMGMAARYLGIHIASPVFDGAREEDVWETLEEAGMSRDAKTVLYDGRTGEPFDNRV SVGIMYMIKLAHMVDDKLHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGA AYTLQEILTVKSDDVVGRVKTYEAIVKGDNVPEPGVPESFKVLIKELQSLGMDVKILS GDEEEIEMRDLEDEEDAKQADGLALSGDEEPEETASADVERDVVTKE*" gene 121919..125500 /gene="rpoB" /locus_tag="BSU_01070" /old_locus_tag="BSU01070" promotor_-10 complement(123504..123523) /Source="Nicolas_upshift_promotors" /id="U91" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=1252 /SigmaFactorBS="acgcggcgatatggcgtttcaATAAAGCCAAaacggtttact ttTGCATAAGATGATAGTGAGTtgatcaaaccgatgttcgggccctcaggcgtttcaa t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(123507) /Source="Nicolas_upshifts" /id="U91" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=1252 /SigmaFactorBS="acgcggcgatatggcgtttcaATAAAGCCAAaacggtttact ttTGCATAAGATGATAGTGAGTtgatcaaaccgatgttcgggccctcaggcgtttcaa t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(123537..123546) /Source="Nicolas_upshift_promotors" /id="U91" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=1252 /SigmaFactorBS="acgcggcgatatggcgtttcaATAAAGCCAAaacggtttact ttTGCATAAGATGATAGTGAGTtgatcaaaccgatgttcgggccctcaggcgtttcaa t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(124375..124379) /Source="Nicolas_upshift_promotors" /id="U92" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.96103896103896" /psig=0 /xcortree=63 /SigmaFactorBS="agatctccgtcttttacttctgccccaatacggatgattcCG CGGTCatcaagattgcgaaGCGCAtcttcaccgacgtttggaatatcgcgagtgattt c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(124380) /Source="Nicolas_upshifts" /id="U92" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.96103896103896" /psig=0 /xcortree=63 /SigmaFactorBS="agatctccgtcttttacttctgccccaatacggatgattcCG CGGTCatcaagattgcgaaGCGCAtcttcaccgacgtttggaatatcgcgagtgattt c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(124394..124400) /Source="Nicolas_upshift_promotors" /id="U92" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.96103896103896" /psig=0 /xcortree=63 /SigmaFactorBS="agatctccgtcttttacttctgccccaatacggatgattcCG CGGTCatcaagattgcgaaGCGCAtcttcaccgacgtttggaatatcgcgagtgattt c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" CDS 125562..129161 /gene="rpoC" /locus_tag="BSU_01080" /old_locus_tag="BSU01080" /EC_number="2.7.7.6" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:10672039, 10675340, 10910724, 11029421, 9795209, 10438769, 23070162, 22720735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10672039, 10675340, 10910724, 11029421, 9795209, 10438769, 23070162, 22720735; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="RNA polymerase (beta' subunit)" /protein_id="NP_387989.2" /db_xref="EnsemblGenomes-Gn:BSU01080" /db_xref="EnsemblGenomes-Tr:CAB11884" /db_xref="GOA:P37871" /db_xref="InterPro:IPR000722" /db_xref="InterPro:IPR006592" /db_xref="InterPro:IPR007066" /db_xref="InterPro:IPR007080" /db_xref="InterPro:IPR007081" /db_xref="InterPro:IPR007083" /db_xref="InterPro:IPR012754" /db_xref="SubtiList:BG10729" /db_xref="UniProtKB/Swiss-Prot:P37871" /translation="MLDVNNFEYMNIGLASPDKIRSWSFGEVKKPETINYRTLKPEKD GLFCERIFGPTKDWECHCGKYKRVRYKGVVCDRCGVEVTRAKVRRERMGHIELAAPVS HIWYFKGIPSRMGLVLDMSPRALEEVIYFASYVVTDPANTPLEKKQLLSEKEYRAYLD KYGNKFQASMGAEAIHKLLQDIDLVKEVDMLKEELKTSQGQRRTRAIKRLEVLEAFRN SGNKPSWMILDVLPVIPPELRPMVQLDGGRFATSDLNDLYRRVINRNNRLKRLLDLGA PSIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRFRQNLLGK RVDYSGRSVIVVGPHLKMYQCGLPKEMALELFKPFVMKELVEKGLAHNIKSAKRKIER VQPEVWDVLESVIKEHPVLLNRAPTLHRLGIQAFEPTLVEGRAIRLHPLVCTAYNADF DGDQMAVHVPLSAEAQAEARILMLAAQNILNPKDGKPVVTPSQDMVLGNYYLTLERAG AVGEGMVFKNTDEALLAYQNGYVHLHTRVAVAANSLKNVTFTEEQRSKLLITTVGKLV FNEILPESFPYMNEPTKSNIEEKTPDRFFLEKGADVKAVIAQQPINAPFKKGILGKII AEIFKRFHITETSKMLDRMKNLGFKYSTKAGITVGVSDIVVLDDKQEILEEAQSKVDN VMKQFRRGLITEEERYERVISIWSAAKDVIQGKLMKSLDELNPIYMMSDSGARGNASN FTQLAGMRGLMANPAGRIIELPIKSSFREGLTVLEYFISTHGARKGLADTALKTADSG YLTRRLVDVAQDVIIRETDCGTDRGILAKPLKEGTETIERLEERLIGRFARKQVKHPE TGEVLVNENELIDEDKALEIVEAGIEEVWIRSAFTCNTPHGVCKRCYGRNLATGSDVE VGEAVGIIAAQSIGEPGTQLTMRTFHTGGVAGDDITQGLPRIQELFEARNPKGQATIT EIDGTVVEINEVRDKQQEIVVQGAVETRSYTAPYNSRLKVAEGDKITRGQVLTEGSID PKELLKVTDLTTVQEYLLHEVQKVYRMQGVEIGDKHVEVMVRQMLRKVRVIDAGDTDV LPGTLLDIHQFTEANKKVLLEGNRPATGRPVLLGITKASLETDSFLSAASFQETTRVL TDAAIKGKRDELLGLKENVIIGKLVPAGTGMMKYRKVKPVSNVQPTDDMVPVE*" gene 125562..129161 /gene="rpoC" /locus_tag="BSU_01080" /old_locus_tag="BSU01080" downshifts complement(128626) /Source="Nicolas_upshifts" /id="D46" /incds=1 /nref=1 /ntot=76 /MaxReadThrough="3.40002" /MaxDrop="2.38911" /score="-2.05539956" /energy="-7.5" /TU="U93" /idTUdmin="U93" /TUdmin="-132" /isTUend="FALSE" upshifts complement(128780) /Source="Nicolas_upshifts" /id="U93" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.952047952047952" /psig="0.000999000999001" /xcortree=64 /SigmaFactorBS="caatgtacctggaagcacatcagtgtcaccggcatcaatcaC Gcgtactttgcgaagcatctggcgaaccattacttctacgtgtttatcaccgatttca a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" misc_feature complement(128798..128799) /Source="Nicolas_upshift_promotors" /id="U93" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.952047952047952" /psig="0.000999000999001" /xcortree=64 /SigmaFactorBS="caatgtacctggaagcacatcagtgtcaccggcatcaatcaC Gcgtactttgcgaagcatctggcgaaccattacttctacgtgtttatcaccgatttca a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" downshifts complement(129110) /Source="Nicolas_upshifts" /id="D47" /incds=0 /nref=98 /ntot=210 /MaxReadThrough="1.61828" /MaxDrop="4.90549" /score="-2.05539956" /energy="-7.5" /TU="NA" /idTUdmin="U95" /TUdmin=0 /isTUend="TRUE" S_feature 129162..129283 /Source="Nicolas_S_feature" /locus_tag="new_129162_129283" /HighExp="LoTm, HiOs, S3, SMMPr, Heat, S1, BC, Glu, S4, MG 45" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="0.997, 1" /TUlongSig="SigA, SigK, SigA, SigWXY, SigA, SigB, SigA" /TUlongPSig="1, 1, 0.999, 1, 1, 1, 0.947" /label="S52" promotor_-35 129265..129272 /Source="Nicolas_upshift_promotors" /id="U94" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.781218781218781" /psig=1 /xcortree=2650 /SigmaFactorBS="cactctatgagaagaacgaatctaaaaaatgtcataccttGT TGACATtcgtctcctagaaTGATAATATAACCAAGGTGCtcgaaataaacctgttact t" /listShort="rplGB, S53, rpsL, rpsG, fusA, S54, tufA, ybaC" /listLong="S55, rpsJ, rplC, rplD, rplW, rplB, rpsS, rplV, rpsC, rplP, rpmC, rpsQ, rplNA, rplX, rplE, rpsNA, rpsH, rplF, rplR, rpsE, rpmD, rplO, secY, adk, mapA, ybzG, infA, rpmJ, rpsM, rpsK, S56, rpoA, rplQ, S57, ybxA, ybaE, ybaF, truA, NA, rplM, rpsI, S59, ybaJ" /label="promotor_-35" upshifts 129285 /Source="Nicolas_upshifts" /id="U94" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.781218781218781" /psig=1 /xcortree=2650 /SigmaFactorBS="cactctatgagaagaacgaatctaaaaaatgtcataccttGT TGACATtcgtctcctagaaTGATAATATAACCAAGGTGCtcgaaataaacctgttact t" /listShort="rplGB, S53, rpsL, rpsG, fusA, S54, tufA, ybaC" /listLong="S55, rpsJ, rplC, rplD, rplW, rplB, rpsS, rplV, rpsC, rplP, rpmC, rpsQ, rplNA, rplX, rplE, rpsNA, rpsH, rplF, rplR, rpsE, rpmD, rplO, secY, adk, mapA, ybzG, infA, rpmJ, rpsM, rpsK, S56, rpoA, rplQ, S57, ybxA, ybaE, ybaF, truA, NA, rplM, rpsI, S59, ybaJ" promotor_-10 129286..129305 /Source="Nicolas_upshift_promotors" /id="U94" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.781218781218781" /psig=1 /xcortree=2650 /SigmaFactorBS="cactctatgagaagaacgaatctaaaaaatgtcataccttGT TGACATtcgtctcctagaaTGATAATATAACCAAGGTGCtcgaaataaacctgttact t" /listShort="rplGB, S53, rpsL, rpsG, fusA, S54, tufA, ybaC" /listLong="S55, rpsJ, rplC, rplD, rplW, rplB, rpsS, rplV, rpsC, rplP, rpmC, rpsQ, rplNA, rplX, rplE, rpsNA, rpsH, rplF, rplR, rpsE, rpmD, rplO, secY, adk, mapA, ybzG, infA, rpmJ, rpsM, rpsK, S56, rpoA, rplQ, S57, ybxA, ybaE, ybaF, truA, NA, rplM, rpsI, S59, ybaJ" /label="promotor_-10" misc_feature complement(129303..129307) /Source="Nicolas_upshift_promotors" /id="U95" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.909090909090909" /psig="0.023976023976024" /xcortree=67 /SigmaFactorBS="ggcctgtgatactttatcataagacataaacatatcctccaa agtaacaggtttatttcGAGCAccttggttatattatcattctaggagacgaatgtca a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(129306) /Source="Nicolas_upshifts" /id="U95" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.909090909090909" /psig="0.023976023976024" /xcortree=67 /SigmaFactorBS="ggcctgtgatactttatcataagacataaacatatcctccaa agtaacaggtttatttcGAGCAccttggttatattatcattctaggagacgaatgtca a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" CDS 129340..129588 /gene="rulS" /locus_tag="BSU_01090" /old_locus_tag="BSU01090" /function="16.8: Protect" /function="16.13: Shape" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:11574053, 11948165, 17468242, 7657605, 22355167, 23249744, 24204571, 22720735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11574053, 11948165, 17468242, 7657605, 22355167, 23249744, 24204571, 22720735; Product type s: structure" /codon_start=1 /transl_table=11 /product="K-turn RNA binding protein; alternative ribosomal protein L7A" /protein_id="NP_387990.1" /db_xref="EnsemblGenomes-Gn:BSU01090" /db_xref="EnsemblGenomes-Tr:CAB11885" /db_xref="GOA:P46350" /db_xref="InterPro:IPR000948" /db_xref="InterPro:IPR004038" /db_xref="InterPro:IPR023460" /db_xref="InterPro:IPR029064" /db_xref="PDB:3V7E" /db_xref="PDB:4LCK" /db_xref="PDB:4TZP" /db_xref="PDB:4TZV" /db_xref="PDB:4TZW" /db_xref="PDB:4TZZ" /db_xref="SubtiList:BG11365" /db_xref="UniProtKB/Swiss-Prot:P46350" /translation="MSYDKVSQAKSIIIGTKQTVKALKRGSVKEVVVAKDADPILTSS VVSLAEDQGISVSMVESMKKLGKACGIEVGAAAVAIIL*" gene 129340..129588 /gene="rulS" /locus_tag="BSU_01090" /old_locus_tag="BSU01090" S_feature 129589..129701 /Source="Nicolas_S_feature" /locus_tag="new_129589_129701" /HighExp="T-3.40H, M/G, T-1.40H, T-5.40H, Salt, Mal, T-0.40H, G/S, M9-exp, Diami" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA, SigA" /TUshortPSig="1, 0.997, 1" /TUlongSig="SigA, SigK, SigA, SigWXY, SigA, SigB, SigA" /TUlongPSig="1, 1, 0.999, 1, 1, 1, 0.947" /label="S53" CDS 129702..130118 /gene="rpsL" /locus_tag="BSU_01100" /old_locus_tag="BSU01100" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:11489846, 12682299, 16484214, 18252828, 19383706, 20007320" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11489846, 12682299, 16484214, 18252828, 19383706, 20007320; Product type s : structure" /codon_start=1 /transl_table=11 /product="ribosomal protein S12 (BS12)" /protein_id="NP_387991.2" /db_xref="EnsemblGenomes-Gn:BSU01100" /db_xref="EnsemblGenomes-Tr:CAB11886" /db_xref="GOA:P21472" /db_xref="InterPro:IPR005679" /db_xref="InterPro:IPR006032" /db_xref="InterPro:IPR012340" /db_xref="PDB:3J9W" /db_xref="PDB:5NJT" /db_xref="SubtiList:BG19009" /db_xref="UniProtKB/Swiss-Prot:P21472" /translation="MPTINQLIRKGRVSKVENSKSPALNKGYNSFKKEHTNVSSPQKR GVCTRVGTMTPKKPNSALRKYARVRLTNGIEVTAYIPGIGHNLQEHSVVLIRGGRVKD LPGVRYHIVRGALDTAGVENRAQGRSKYGTKKPKAK*" gene 129702..130118 /gene="rpsL" /locus_tag="BSU_01100" /old_locus_tag="BSU01100" CDS 130160..130630 /gene="rpsG" /locus_tag="BSU_01110" /old_locus_tag="BSU01110" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:8722036, 12682299, 19653700" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8722036, 12682299, 19653700; Product type s: structure" /codon_start=1 /transl_table=11 /product="ribosomal protein S7 (BS7)" /protein_id="NP_387992.2" /db_xref="EnsemblGenomes-Gn:BSU01110" /db_xref="EnsemblGenomes-Tr:CAB11887" /db_xref="GOA:P21469" /db_xref="InterPro:IPR000235" /db_xref="InterPro:IPR005717" /db_xref="InterPro:IPR020606" /db_xref="InterPro:IPR023798" /db_xref="InterPro:IPR036823" /db_xref="PDB:3J9W" /db_xref="PDB:5NJT" /db_xref="SubtiList:BG19006" /db_xref="UniProtKB/Swiss-Prot:P21469" /translation="MPRKGPVAKRDVLPDPIYNSKLVSRLINKMMIDGKKGKSQTILY KSFDIIKERTGNDAMEVFEQALKNIMPVLEVKARRVGGANYQVPVEVRPERRTTLGLR WLVNYARLRGEKTMEERLANEILDAANNTGAAVKKREDTHKMAEANKAFAHYRW*" gene 130160..130630 /gene="rpsG" /locus_tag="BSU_01110" /old_locus_tag="BSU01110" CDS 130684..132762 /gene="fusA" /locus_tag="BSU_01120" /old_locus_tag="BSU01120" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:815236, 815243, 1556067, 4629789, 19366171, 22720735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 815236, 815243, 1556067, 4629789, 19366171, 22720735; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="elongation factor G" /protein_id="NP_387993.2" /db_xref="EnsemblGenomes-Gn:BSU01120" /db_xref="EnsemblGenomes-Tr:CAB11888" /db_xref="GOA:P80868" /db_xref="InterPro:IPR000640" /db_xref="InterPro:IPR000795" /db_xref="InterPro:IPR004161" /db_xref="InterPro:IPR004540" /db_xref="InterPro:IPR005225" /db_xref="InterPro:IPR005517" /db_xref="InterPro:IPR009000" /db_xref="InterPro:IPR009022" /db_xref="InterPro:IPR014721" /db_xref="InterPro:IPR020568" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR031157" /db_xref="InterPro:IPR035647" /db_xref="InterPro:IPR035649" /db_xref="PDB:5VH6" /db_xref="SubtiList:BG11939" /db_xref="UniProtKB/Swiss-Prot:P80868" /translation="MAREFSLEKTRNIGIMAHIDAGKTTTTERILFYTGRIHKIGETH EGASQMDWMEQEQERGITITSAATTAQWKGYRVNIIDTPGHVDFTVEVERSLRVLDGA VAVLDAQSGVEPQTETVWRQATTYGVPRIVFVNKMDKIGADFLYSVGTLRDRLQANAH AIQLPIGAEDNFEGIIDLVENVAYFYEDDLGTRSDAKEIPEEYKEQAEELRNSLIEAV CELDEELMDKYLEGEEITIDELKAGIRKGTLNVEFYPVLVGSAFKNKGVQLVLDAVLD YLPAPTDVAAIKGTRPDTNEEIERHSSDEEPFSALAFKVMTDPYVGKLTFFRVYSGTL DSGSYVKNSTKGKRERVGRILQMHANSREEISTVYAGDIAAAVGLKDTTTGDTLCDEK DLVILESMEFPEPVIDVAIEPKSKADQDKMGIALAKLAEEDPTFRTQTNPETGQTIIS GMGELHLDIIVDRMKREFKVEANVGAPQVAYRETFRTGAKVEGKFVRQSGGRGQFGHV WIEFEPNEEGAGFEFENAIVGGVVPREYIPAVQAGLEDALENGVLAGFPLIDIKAKLF DGSYHDVDSNEMAFKVAASMALKNAVSKCNPVLLEPIMKVEVVIPEEYMGDIMGDITS RRGRVEGMEARGNAQVVRAMVPLAEMFGYATALRSNTQGRGTFTMHMDHYEEVPKSVA EEIIKKNKGE*" gene 130684..132762 /gene="fusA" /locus_tag="BSU_01120" /old_locus_tag="BSU01120" S_feature 132763..132881 /Source="Nicolas_S_feature" /locus_tag="new_132763_132881" /HighExp="T-5.40H, T-4.40H, UNK1, SMM, HiTm, T-3.40H, T-2.40H, SMMPr, MG 90, MG 15" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA, SigA" /TUshortPSig="1, 0.997, 1" /TUlongSig="SigA, SigK, SigA, SigWXY, SigA, SigB, SigA" /TUlongPSig="1, 1, 0.999, 1, 1, 1, 0.947" /label="S54" CDS 132882..134072 /gene="tufA" /locus_tag="BSU_01130" /old_locus_tag="BSU01130" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:10774755, 12682299, 7706132, 20133608, 22938038, 22720735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10774755, 12682299, 7706132, 20133608, 22938038, 22720735; Product type f : factor" /codon_start=1 /transl_table=11 /product="elongation factor Tu" /protein_id="NP_387994.1" /db_xref="EnsemblGenomes-Gn:BSU01130" /db_xref="EnsemblGenomes-Tr:CAB11889" /db_xref="GOA:P33166" /db_xref="InterPro:IPR000795" /db_xref="InterPro:IPR004160" /db_xref="InterPro:IPR004161" /db_xref="InterPro:IPR004541" /db_xref="InterPro:IPR005225" /db_xref="InterPro:IPR009000" /db_xref="InterPro:IPR009001" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR031157" /db_xref="InterPro:IPR033720" /db_xref="SubtiList:BG11056" /db_xref="UniProtKB/Swiss-Prot:P33166" /translation="MAKEKFDRSKSHANIGTIGHVDHGKTTLTAAITTVLHKKSGKGT AMAYDQIDGAPEERERGITISTAHVEYETETRHYAHVDCPGHADYVKNMITGAAQMDG AILVVSAADGPMPQTREHILLSKNVGVPYIVVFLNKCDMVDDEELLELVEMEVRDLLS EYDFPGDDVPVVKGSALKALEGDAEWEAKIFELMDAVDEYIPTPERDTEKPFMMPVED VFSITGRGTVATGRVERGQVKVGDEVEIIGLQEENKKTTVTGVEMFRKLLDYAEAGDN IGALLRGVSREEIQRGQVLAKPGTITPHSKFKAEVYVLSKEEGGRHTPFFSNYRPQFY FRTTDVTGIIHLPEGVEMVMPGDNTEMNVELISTIAIEEGTRFSIREGGRTVGSGVVS TITE*" gene 132882..134072 /gene="tufA" /locus_tag="BSU_01130" /old_locus_tag="BSU01130" downshifts 134067 /Source="Nicolas_upshifts" /id="D48" /incds=0 /nref=258 /ntot=269 /MaxReadThrough="4.84568" /MaxDrop="8.56168" /score="39.3984056" /energy="-12.9" /TU="U88,U90,U94" /idTUdmin="U88" /TUdmin="-1081" /isTUend="FALSE" misc_feature complement(134098..134101) /Source="Nicolas_upshift_promotors" /id="U96" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.917082917082917" /psig="0.001998001998002" /xcortree=68 /SigmaFactorBS="acccctcgaatatgatagatcctattatacaagaaaaagata agcaaacaaaaaacgagacCCACaggggtctcgtttaaaaccatactattactcagtg a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(134102) /Source="Nicolas_upshifts" /id="U96" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.917082917082917" /psig="0.001998001998002" /xcortree=68 /SigmaFactorBS="acccctcgaatatgatagatcctattatacaagaaaaagata agcaaacaaaaaacgagacCCACaggggtctcgtttaaaaccatactattactcagtg a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" misc_feature 134128..134147 /Source="Nicolas_upshift_promotors" /id="U97" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.846153846153846" /psig=1 /xcortree=1878 /SigmaFactorBS="tatggttttaaacgagacccctgtgggtctcgttttttgttt gcttatctttTTCTTGTATAATAGGATCTAtcatattcgaggggttaatatttatgat t" /listShort="ybaC" /listLong="S55, rpsJ, rplC, rplD, rplW, rplB, rpsS, rplV, rpsC, rplP, rpmC, rpsQ, rplNA, rplX, rplE, rpsNA, rpsH, rplF, rplR, rpsE, rpmD, rplO, secY, adk, mapA, ybzG, infA, rpmJ, rpsM, rpsK, S56, rpoA, rplQ, S57, ybxA, ybaE, ybaF, truA, NA, rplM, rpsI, S59, ybaJ" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 134136 /Source="Nicolas_upshifts" /id="U97" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.846153846153846" /psig=1 /xcortree=1878 /SigmaFactorBS="tatggttttaaacgagacccctgtgggtctcgttttttgttt gcttatctttTTCTTGTATAATAGGATCTAtcatattcgaggggttaatatttatgat t" /listShort="ybaC" /listLong="S55, rpsJ, rplC, rplD, rplW, rplB, rpsS, rplV, rpsC, rplP, rpmC, rpsQ, rplNA, rplX, rplE, rpsNA, rpsH, rplF, rplR, rpsE, rpmD, rplO, secY, adk, mapA, ybzG, infA, rpmJ, rpsM, rpsK, S56, rpoA, rplQ, S57, ybxA, ybaE, ybaF, truA, NA, rplM, rpsI, S59, ybaJ" CDS 134171..135127 /gene="ybaC" /locus_tag="BSU_01140" /old_locus_tag="BSU01140" /EC_number="3.4.11.5" /function="16.11: Scavenge (Catabolism)" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative proline iminopeptidase" /protein_id="NP_387995.2" /db_xref="EnsemblGenomes-Gn:BSU01140" /db_xref="EnsemblGenomes-Tr:CAB11890" /db_xref="GOA:P70981" /db_xref="InterPro:IPR002410" /db_xref="InterPro:IPR022742" /db_xref="InterPro:IPR029058" /db_xref="SubtiList:BG11988" /db_xref="UniProtKB/Swiss-Prot:P70981" /translation="MIPEKKSIAIMKELSIGNTKQMLMINGVDVKNPLLLFLHGGPGT PQIGYVRHYQKELEQYFTVVHWDQRGSGLSYSKRISHHSMTINHFIKDTIQVTQWLLA HFSKSKLYLAGHSWGSILALHVLQQRPDLFYTYYGISQVVNPQDEESTAYQHIREISE SKKASILSFLTRFIGAPPWKQDIQHLIYRFCVELTRGGFTHRHRQSLAVLFQMLTGNE YGVRNMHSFLNGLRFSKKHLTDELYRFNAFTSVPSIKVPCVFISGKHDLIVPAEISKQ YYQELEAPEKRWFQFENSAHTPHIEEPSLFANTLSRHARHHL*" gene 134171..135127 /gene="ybaC" /locus_tag="BSU_01140" /old_locus_tag="BSU01140" promotor_-35 135134..135141 /Source="Nicolas_upshift_promotors" /id="U98" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.633366633366633" /psig=1 /xcortree=2656 /SigmaFactorBS="gcacgacaccatttatgatagatcCTTGATAAataagaaaaa cccCTGTATAATAAAAAAAGTGTgcaaatcatgcatattttaaataagtcttgcaaca t" /listShort="S55, rpsJ, rplC, rplD, rplW, rplB, rpsS, rplV, rpsC, rplP, rpmC, rpsQ, rplNA, rplX, rplE, rpsNA, rpsH, rplF, rplR, rpsE, rpmD, rplO, secY, adk, mapA, ybzG, infA, rpmJ, rpsM, rpsK, S56, rpoA, rplQ, S57, ybxA, ybaE, ybaF, truA, NA, rplM, rpsI, S59, ybaJ" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 135155..135174 /Source="Nicolas_upshift_promotors" /id="U98" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.633366633366633" /psig=1 /xcortree=2656 /SigmaFactorBS="gcacgacaccatttatgatagatcCTTGATAAataagaaaaa cccCTGTATAATAAAAAAAGTGTgcaaatcatgcatattttaaataagtcttgcaaca t" /listShort="S55, rpsJ, rplC, rplD, rplW, rplB, rpsS, rplV, rpsC, rplP, rpmC, rpsQ, rplNA, rplX, rplE, rpsNA, rpsH, rplF, rplR, rpsE, rpmD, rplO, secY, adk, mapA, ybzG, infA, rpmJ, rpsM, rpsK, S56, rpoA, rplQ, S57, ybxA, ybaE, ybaF, truA, NA, rplM, rpsI, S59, ybaJ" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 135170..135363 /Source="Nicolas_S_feature" /locus_tag="new_135170_135363" /HighExp="T-1.40H, T-2.40H, T-1.10H, SMM, T-3.40H, T-4.40H, BI, BMM, H2O2, nit" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="SigA, SigA, SigA, SigA, SigA, SigA, SigWXY, SigA, SigA" /TUlongPSig="1, 1, 0.997, 1, 1, 0.999, 1, 1, 0.947" /label="S55" upshifts 135170 /Source="Nicolas_upshifts" /id="U98" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.633366633366633" /psig=1 /xcortree=2656 /SigmaFactorBS="gcacgacaccatttatgatagatcCTTGATAAataagaaaaa cccCTGTATAATAAAAAAAGTGTgcaaatcatgcatattttaaataagtcttgcaaca t" /listShort="S55, rpsJ, rplC, rplD, rplW, rplB, rpsS, rplV, rpsC, rplP, rpmC, rpsQ, rplNA, rplX, rplE, rpsNA, rpsH, rplF, rplR, rpsE, rpmD, rplO, secY, adk, mapA, ybzG, infA, rpmJ, rpsM, rpsK, S56, rpoA, rplQ, S57, ybxA, ybaE, ybaF, truA, NA, rplM, rpsI, S59, ybaJ" /GFF_Attribute="listLong" CDS 135364..135672 /gene="rpsJ" /locus_tag="BSU_01150" /old_locus_tag="BSU01150" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:12682299, 27964882" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12682299, 27964882; Product type s: structure" /codon_start=1 /transl_table=11 /product="ribosomal protein S10 (BS13); transcription antitermination factor" /protein_id="NP_387996.1" /db_xref="EnsemblGenomes-Gn:BSU01150" /db_xref="EnsemblGenomes-Tr:CAB11891" /db_xref="GOA:P21471" /db_xref="InterPro:IPR001848" /db_xref="InterPro:IPR018268" /db_xref="InterPro:IPR027486" /db_xref="InterPro:IPR036838" /db_xref="PDB:3J9W" /db_xref="PDB:5NJT" /db_xref="SubtiList:BG19008" /db_xref="UniProtKB/Swiss-Prot:P21471" /translation="MAKQKIRIRLKAYDHRILDQSAEKIVETAKRSGASVSGPIPLPT EKSVYTILRAVHKYKDSREQFEMRTHKRLIDIVNPTPQTVDALMRLDLPSGVDIEIKL *" gene 135364..135672 /gene="rpsJ" /locus_tag="BSU_01150" /old_locus_tag="BSU01150" CDS 135712..136341 /gene="rplC" /locus_tag="BSU_01160" /old_locus_tag="BSU01160" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:12682299, 17981968, 19154332, 23759864" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12682299, 17981968, 19154332, 23759864; Product type s: structure" /codon_start=1 /transl_table=11 /product="ribosomal protein L3 (BL3)" /protein_id="NP_387997.1" /db_xref="EnsemblGenomes-Gn:BSU01160" /db_xref="EnsemblGenomes-Tr:CAB11892" /db_xref="GOA:P42920" /db_xref="InterPro:IPR000597" /db_xref="InterPro:IPR009000" /db_xref="InterPro:IPR019926" /db_xref="InterPro:IPR019927" /db_xref="PDB:3J3V" /db_xref="PDB:3J3W" /db_xref="PDB:3J9W" /db_xref="PDB:5NJT" /db_xref="SubtiList:BG11218" /db_xref="UniProtKB/Swiss-Prot:P42920" /translation="MTKGILGRKIGMTQVFAENGDLIPVTVIEAAPNVVLQKKTAEND GYEAIQLGFDDKREKLSNKPEKGHVAKAETAPKRFVKELRGVEMDAYEVGQEVKVEIF SAGEIVDVTGVSKGKGFQGAIKRHGQSRGPMSHGSRYHRRPGSMGPVDPNRVFKGKLL PGRMGGEQITVQNLEIVKVDAERNLLLIKGNVPGAKKSLITVKSAVKSK*" gene 135712..136341 /gene="rplC" /locus_tag="BSU_01160" /old_locus_tag="BSU01160" CDS 136369..136992 /gene="rplD" /locus_tag="BSU_01170" /old_locus_tag="BSU01170" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 10898684, 12682299, 22720735; Product type s: structure" /codon_start=1 /transl_table=11 /product="ribosomal protein L4" /protein_id="NP_387998.1" /db_xref="EnsemblGenomes-Gn:BSU01170" /db_xref="EnsemblGenomes-Tr:CAB11893" /db_xref="GOA:P42921" /db_xref="InterPro:IPR002136" /db_xref="InterPro:IPR013005" /db_xref="InterPro:IPR023574" /db_xref="PDB:3J3V" /db_xref="PDB:3J3W" /db_xref="PDB:3J9W" /db_xref="PDB:5NJT" /db_xref="SubtiList:BG11219" /db_xref="UniProtKB/Swiss-Prot:P42921" /translation="MPKVALYNQNGSTAGDIELNASVFGIEPNESVVFDAILMQRASL RQGTHKVKNRSEVRGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYSYKLP KKVRRLAIKSVLSSKVIDNNIIVLEDLTLDTAKTKEMAAILKGLSVEKKALIVTADAN EAVALSARNIPGVTVVEANGINVLDVVNHEKLLITKAAVEKVEEVLA*" gene 136369..136992 /gene="rplD" /locus_tag="BSU_01170" /old_locus_tag="BSU01170" CDS 136992..137279 /gene="rplW" /locus_tag="BSU_01180" /old_locus_tag="BSU01180" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:12682299, 17981968, 23002217" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12682299, 17981968, 23002217; Product type s: structure" /codon_start=1 /transl_table=11 /product="ribosomal protein L23" /protein_id="NP_387999.2" /db_xref="EnsemblGenomes-Gn:BSU01180" /db_xref="EnsemblGenomes-Tr:CAB11894" /db_xref="GOA:P42924" /db_xref="InterPro:IPR001014" /db_xref="InterPro:IPR012678" /db_xref="InterPro:IPR013025" /db_xref="PDB:3J3V" /db_xref="PDB:3J3W" /db_xref="PDB:3J9W" /db_xref="PDB:5NJT" /db_xref="SubtiList:BG11221" /db_xref="UniProtKB/Swiss-Prot:P42924" /translation="MKDPRDVLKRPVITERSADLMTEKKYTFEVDVRANKTEVKDAVE SIFGVKVDKVNIMNYKGKSKRVGRYTGMTSRRRKAIVKLTADSKEIEIFEA*" gene 136992..137279 /gene="rplW" /locus_tag="BSU_01180" /old_locus_tag="BSU01180" CDS 137311..138144 /gene="rplB" /locus_tag="BSU_01190" /old_locus_tag="BSU01190" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:12682299, 23249812, 24637032" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12682299, 23249812, 24637032; Product type s: structure" /codon_start=1 /transl_table=11 /product="ribosomal protein L2 (BL2)" /protein_id="NP_388000.2" /db_xref="EnsemblGenomes-Gn:BSU01190" /db_xref="EnsemblGenomes-Tr:CAB11895" /db_xref="GOA:P42919" /db_xref="InterPro:IPR002171" /db_xref="InterPro:IPR005880" /db_xref="InterPro:IPR008991" /db_xref="InterPro:IPR012340" /db_xref="InterPro:IPR014722" /db_xref="InterPro:IPR014726" /db_xref="InterPro:IPR022666" /db_xref="InterPro:IPR022669" /db_xref="InterPro:IPR022671" /db_xref="PDB:3J3V" /db_xref="PDB:3J3W" /db_xref="PDB:3J9W" /db_xref="PDB:5NJT" /db_xref="SubtiList:BG11217" /db_xref="UniProtKB/Swiss-Prot:P42919" /translation="MAIKKYKPTSNGRRGMTTSDFAEITTDKPEKSLLAPLHKKGGRN NQGKLTVRHQGGGHKRQYRVIDFKRDKDGIPGRVATVEYDPNRSANIALINYADGEKR YILAPKGIQVGTEIMSGPEADIKVGNALPLINIPVGTVVHNIELKPGKGGQLVRSAGT SAQVLGKEGKYVLVRLNSGEVRMILSACRASIGQVGNEQHELINIGKAGRSRWKGIRP TVRGSVMNPNDHPHGGGEGRAPIGRKSPMSPWGKPTLGFKTRKKKNKSDKFIVRRRKN K*" gene 137311..138144 /gene="rplB" /locus_tag="BSU_01190" /old_locus_tag="BSU01190" downshifts complement(137447) /Source="Nicolas_upshifts" /id="D49" /incds=1 /nref=1 /ntot=47 /MaxReadThrough="3.39972" /MaxDrop="4.09052" /score="-4.16840603" /energy="-12.8" /TU="NA" /idTUdmin="U99" /TUdmin=1342 /isTUend="FALSE" CDS 138202..138480 /gene="rpsS" /locus_tag="BSU_01200" /old_locus_tag="BSU01200" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 12682299; Product type s : structure" /codon_start=1 /transl_table=11 /product="ribosomal protein S19 (BS19)" /protein_id="NP_388001.1" /db_xref="EnsemblGenomes-Gn:BSU01200" /db_xref="EnsemblGenomes-Tr:CAB11896" /db_xref="GOA:P21476" /db_xref="InterPro:IPR002222" /db_xref="InterPro:IPR005732" /db_xref="InterPro:IPR020934" /db_xref="InterPro:IPR023575" /db_xref="PDB:3J9W" /db_xref="PDB:5NJT" /db_xref="SubtiList:BG19011" /db_xref="UniProtKB/Swiss-Prot:P21476" /translation="MARSLKKGPFVDGHLMTKIEKLNETDKKQVVKTWSRRSTIFPQF IGHTIAVYDGRKHVPVFISEDMVGHKLGEFAPTRTYKGHASDDKKTRR*" gene 138202..138480 /gene="rpsS" /locus_tag="BSU_01200" /old_locus_tag="BSU01200" CDS 138497..138838 /gene="rplV" /locus_tag="BSU_01210" /old_locus_tag="BSU01210" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:7928988, 12682299, 23002217" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7928988, 12682299, 23002217; Product type s: structure" /codon_start=1 /transl_table=11 /product="ribosomal protein L22 (BL17)" /protein_id="NP_388002.1" /db_xref="EnsemblGenomes-Gn:BSU01210" /db_xref="EnsemblGenomes-Tr:CAB11897" /db_xref="GOA:P42060" /db_xref="InterPro:IPR001063" /db_xref="InterPro:IPR005727" /db_xref="InterPro:IPR018260" /db_xref="InterPro:IPR036394" /db_xref="PDB:3J3V" /db_xref="PDB:3J3W" /db_xref="PDB:3J9W" /db_xref="PDB:5NJT" /db_xref="SubtiList:BG11078" /db_xref="UniProtKB/Swiss-Prot:P42060" /translation="MQAKAVARTVRIAPRKARLVMDLIRGKQVGEAVSILNLTPRAAS PIIEKVLKSAIANAEHNYEMDANNLVISQAFVDEGPTLKRFRPRAMGRASQINKRTSH ITIVVSEKKEG*" gene 138497..138838 /gene="rplV" /locus_tag="BSU_01210" /old_locus_tag="BSU01210" CDS 138842..139498 /gene="rpsC" /locus_tag="BSU_01220" /old_locus_tag="BSU01220" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:12682299" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12682299; Product type s: structure" /codon_start=1 /transl_table=11 /product="ribosomal protein S3 (BS3)" /protein_id="NP_388003.2" /db_xref="EnsemblGenomes-Gn:BSU01220" /db_xref="EnsemblGenomes-Tr:CAB11898" /db_xref="GOA:P21465" /db_xref="InterPro:IPR001351" /db_xref="InterPro:IPR004044" /db_xref="InterPro:IPR004087" /db_xref="InterPro:IPR005704" /db_xref="InterPro:IPR009019" /db_xref="InterPro:IPR015946" /db_xref="InterPro:IPR018280" /db_xref="InterPro:IPR036419" /db_xref="PDB:3J9W" /db_xref="PDB:5NJT" /db_xref="SubtiList:BG19005" /db_xref="UniProtKB/Swiss-Prot:P21465" /translation="MGQKVNPVGLRIGVIRDWESKWYAGKDYADFLHEDLKIREYISK RLSDASVSKVEIERAANRVNITIHTAKPGMVIGKGGSEVEALRKALNSLTGKRVHINI LEIKRADLDAQLVADNIARQLENRVSFRRAQKQQIQRTMRAGAQGVKTMVSGRLGGAD IARSEYYSEGTVPLHTLRADIDYATSEADTTYGKLGVKVWIYRGEVLPTKKKNEEGGK *" gene 138842..139498 /gene="rpsC" /locus_tag="BSU_01220" /old_locus_tag="BSU01220" downshifts complement(138855) /Source="Nicolas_upshifts" /id="D50" /incds=0 /nref=1 /ntot=62 /MaxReadThrough="3.68388" /MaxDrop="2.1922" /score="-4.16840603" /energy="-12.8" /TU="U99" /idTUdmin="U99" /TUdmin="-66" /isTUend="FALSE" promotor_-10 complement(138936..138940) /Source="Nicolas_upshift_promotors" /id="U99" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.972027972027972" /psig="0.00999000999001" /xcortree=77 /SigmaFactorBS="tactttagaaacagaagcgtcagaaaggcgtttgctaatgta ttCACgaatttttaaatcttcGTGCAggaagtcagcgtaatctttaccagcgtaccac t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(138943) /Source="Nicolas_upshifts" /id="U99" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.972027972027972" /psig="0.00999000999001" /xcortree=77 /SigmaFactorBS="tactttagaaacagaagcgtcagaaaggcgtttgctaatgta ttCACgaatttttaaatcttcGTGCAggaagtcagcgtaatctttaccagcgtaccac t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(138957..138959) /Source="Nicolas_upshift_promotors" /id="U99" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.972027972027972" /psig="0.00999000999001" /xcortree=77 /SigmaFactorBS="tactttagaaacagaagcgtcagaaaggcgtttgctaatgta ttCACgaatttttaaatcttcGTGCAggaagtcagcgtaatctttaccagcgtaccac t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" CDS 139500..139934 /gene="rplP" /locus_tag="BSU_01230" /old_locus_tag="BSU01230" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:12682299, 16390447, 24335279" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12682299, 16390447, 24335279; Product type s: structure" /codon_start=1 /transl_table=11 /product="ribosomal protein L16" /protein_id="NP_388004.1" /db_xref="EnsemblGenomes-Gn:BSU01230" /db_xref="EnsemblGenomes-Tr:CAB11899" /db_xref="GOA:P14577" /db_xref="InterPro:IPR000114" /db_xref="InterPro:IPR016180" /db_xref="InterPro:IPR020798" /db_xref="InterPro:IPR036920" /db_xref="PDB:3J9W" /db_xref="PDB:5NJT" /db_xref="SubtiList:BG10755" /db_xref="UniProtKB/Swiss-Prot:P14577" /translation="MLLPKRVKYRREHRGKMRGRAKGGTEVHFGEFGIQALEASWITN RQIEAARIAMTRYMKRGGKVWIKIFPSKPYTAKPLEVRMGSGKGAPEGWVAVVKPGKV LFEISGVSEEVAREALRLASHKLPIKTKFVKREEIGGESNES*" gene 139500..139934 /gene="rplP" /locus_tag="BSU_01230" /old_locus_tag="BSU01230" CDS 139924..140124 /gene="rpmC" /locus_tag="BSU_01240" /old_locus_tag="BSU01240" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:12682299, 23002217" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12682299, 23002217; Product type s: structure" /codon_start=1 /transl_table=11 /product="ribosomal protein L29" /protein_id="NP_388005.1" /db_xref="EnsemblGenomes-Gn:BSU01240" /db_xref="EnsemblGenomes-Tr:CAB11900" /db_xref="GOA:P12873" /db_xref="InterPro:IPR001854" /db_xref="InterPro:IPR018254" /db_xref="InterPro:IPR036049" /db_xref="PDB:3J3V" /db_xref="PDB:3J3W" /db_xref="PDB:3J9W" /db_xref="PDB:5NJT" /db_xref="SubtiList:BG10756" /db_xref="UniProtKB/Swiss-Prot:P12873" /translation="MKANEIRDLTTAEIEQKVKSLKEELFNLRFQLATGQLENTARIR EVRKAIARMKTVIREREIAANK*" gene 139924..140124 /gene="rpmC" /locus_tag="BSU_01240" /old_locus_tag="BSU01240" CDS 140147..140410 /gene="rpsQ" /locus_tag="BSU_01250" /old_locus_tag="BSU01250" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:12682299" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12682299; Product type s: structure" /codon_start=1 /transl_table=11 /product="ribosomal protein S17 (BS16)" /protein_id="NP_388006.1" /db_xref="EnsemblGenomes-Gn:BSU01250" /db_xref="EnsemblGenomes-Tr:CAB11901" /db_xref="GOA:P12874" /db_xref="InterPro:IPR000266" /db_xref="InterPro:IPR012340" /db_xref="InterPro:IPR019979" /db_xref="InterPro:IPR019984" /db_xref="PDB:3J9W" /db_xref="PDB:5NJT" /db_xref="SubtiList:BG10757" /db_xref="UniProtKB/Swiss-Prot:P12874" /translation="MSERNQRKVYQGRVVSDKMDKTITVVVETYKKHTLYGKRVKYSK KFKAHDENNQAKIGDIVKIMETRPLSATKRFRLVEVVEEAVII*" gene 140147..140410 /gene="rpsQ" /locus_tag="BSU_01250" /old_locus_tag="BSU01250" CDS 140451..140819 /gene="rplNA" /locus_tag="BSU_01260" /old_locus_tag="BSU01260" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:8722036, 8805509, 12682299, 22829778" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8722036, 8805509, 12682299, 22829778; Product type s: structure" /codon_start=1 /transl_table=11 /product="ribosomal protein L14" /protein_id="NP_388007.1" /db_xref="EnsemblGenomes-Gn:BSU01260" /db_xref="EnsemblGenomes-Tr:CAB11902" /db_xref="GOA:P12875" /db_xref="InterPro:IPR000218" /db_xref="InterPro:IPR005745" /db_xref="InterPro:IPR019972" /db_xref="InterPro:IPR036853" /db_xref="PDB:3J3V" /db_xref="PDB:3J3W" /db_xref="PDB:3J9W" /db_xref="PDB:5NJT" /db_xref="SubtiList:BG10758" /db_xref="UniProtKB/Swiss-Prot:P12875" /translation="MIQQETRLKVADNSGAREVLTIKVLGGSGRKTANIGDVIVCTVK QATPGGVVKKGEVVKAVIVRTKSGARRSDGSYISFDENACVIIRDDKSPRGTRIFGPV ARELRENNFMKIVSLAPEVI*" gene 140451..140819 /gene="rplNA" /locus_tag="BSU_01260" /old_locus_tag="BSU01260" CDS 140857..141168 /gene="rplX" /locus_tag="BSU_01270" /old_locus_tag="BSU01270" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:11278078, 12682299" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11278078, 12682299; Product type s: structure" /codon_start=1 /transl_table=11 /product="ribosomal protein L24 (BL23)" /protein_id="NP_388008.1" /db_xref="EnsemblGenomes-Gn:BSU01270" /db_xref="EnsemblGenomes-Tr:CAB11903" /db_xref="GOA:P0CI78" /db_xref="InterPro:IPR003256" /db_xref="InterPro:IPR005824" /db_xref="InterPro:IPR005825" /db_xref="InterPro:IPR008991" /db_xref="InterPro:IPR014722" /db_xref="PDB:3J3V" /db_xref="PDB:3J3W" /db_xref="PDB:3J9W" /db_xref="PDB:5NJT" /db_xref="SubtiList:BG10759" /db_xref="UniProtKB/Swiss-Prot:P0CI78" /translation="MHVKKGDKVMVISGKDKGKQGTILAAFPKKDRVLVEGVNMVKKH SKPTQANPQGGISNQEAPIHVSNVMPLDPKTGEVTRVGYKVEDGKKVRVAKKSGQVLD K*" gene 140857..141168 /gene="rplX" /locus_tag="BSU_01270" /old_locus_tag="BSU01270" CDS 141195..141734 /gene="rplE" /locus_tag="BSU_01280" /old_locus_tag="BSU01280" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 12682299; Product type s : structure" /codon_start=1 /transl_table=11 /product="ribosomal protein L5 (BL6)" /protein_id="NP_388009.1" /db_xref="EnsemblGenomes-Gn:BSU01280" /db_xref="EnsemblGenomes-Tr:CAB11904" /db_xref="GOA:P12877" /db_xref="InterPro:IPR002132" /db_xref="InterPro:IPR020929" /db_xref="InterPro:IPR020930" /db_xref="InterPro:IPR022803" /db_xref="InterPro:IPR031309" /db_xref="InterPro:IPR031310" /db_xref="PDB:3J3V" /db_xref="PDB:3J9W" /db_xref="PDB:5NJT" /db_xref="SubtiList:BG10760" /db_xref="UniProtKB/Swiss-Prot:P12877" /translation="MNRLKEKYNKEIAPALMTKFNYDSVMQVPKIEKIVINMGVGDAV QNAKAIDSAVEELTFIAGQKPVVTRAKKSIAGFRLREGMPIGAKVTLRGERMYDFLDK LISVSLPRVRDFRGVSKKSFDGRGNYTLGIKEQLIFPEIDYDKVTKVRGMDIVIVTTA NTDEEARELLTQVGMPFQK*" gene 141195..141734 /gene="rplE" /locus_tag="BSU_01280" /old_locus_tag="BSU01280" CDS 141757..141942 /gene="rpsNA" /locus_tag="BSU_01290" /old_locus_tag="BSU01290" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:12682299, 17163968, 19648245, 20208344, 27561249" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12682299, 17163968, 19648245, 20208344, 27561249; Product type s: structure" /codon_start=1 /transl_table=11 /product="ribosomal protein S14" /protein_id="NP_388010.1" /db_xref="EnsemblGenomes-Gn:BSU01290" /db_xref="EnsemblGenomes-Tr:CAB11905" /db_xref="GOA:P12878" /db_xref="InterPro:IPR001209" /db_xref="InterPro:IPR018271" /db_xref="InterPro:IPR023053" /db_xref="PDB:3J9W" /db_xref="PDB:5NJT" /db_xref="SubtiList:BG10761" /db_xref="UniProtKB/Swiss-Prot:P12878" /translation="MAKKSMIAKQQRTPKFKVQEYTRCERCGRPHSVIRKFKLCRICF RELAYKGQIPGVKKASW*" gene 141757..141942 /gene="rpsNA" /locus_tag="BSU_01290" /old_locus_tag="BSU01290" CDS 141974..142372 /gene="rpsH" /locus_tag="BSU_01300" /old_locus_tag="BSU01300" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 12682299; Product type s : structure" /codon_start=1 /transl_table=11 /product="ribosomal protein S8 (BS8)" /protein_id="NP_388011.2" /db_xref="EnsemblGenomes-Gn:BSU01300" /db_xref="EnsemblGenomes-Tr:CAB11906" /db_xref="GOA:P12879" /db_xref="InterPro:IPR000630" /db_xref="InterPro:IPR035987" /db_xref="PDB:3J9W" /db_xref="PDB:5NJT" /db_xref="SubtiList:BG10762" /db_xref="UniProtKB/Swiss-Prot:P12879" /translation="MVMTDPIADMLTRIRNANMVRHEKLEIPASKLKREIAEILKREG FIRDVEFVEDSKQGIIRVFLKYGQNNERVITGLKRISKPGLRVYAKSNEVPRVLNGLG IAIISTSQGVLTDKEARAKQAGGEVLAYVW*" gene 141974..142372 /gene="rpsH" /locus_tag="BSU_01300" /old_locus_tag="BSU01300" downshifts complement(142375) /Source="Nicolas_upshifts" /id="D51" /incds=0 /nref=1 /ntot=74 /MaxReadThrough="2.68318" /MaxDrop="2.55712" /score="5.40276403" /energy="-15.9" /TU="NA" /idTUdmin="U99" /TUdmin="-3586" /isTUend="FALSE" CDS 142402..142941 /gene="rplF" /locus_tag="BSU_01310" /old_locus_tag="BSU01310" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 12682299, 25330043; Product type s: structure" /codon_start=1 /transl_table=11 /product="ribosomal protein L6 (BL8)" /protein_id="NP_388012.1" /db_xref="EnsemblGenomes-Gn:BSU01310" /db_xref="EnsemblGenomes-Tr:CAB11907" /db_xref="GOA:P46898" /db_xref="InterPro:IPR000702" /db_xref="InterPro:IPR002358" /db_xref="InterPro:IPR019906" /db_xref="InterPro:IPR020040" /db_xref="InterPro:IPR036789" /db_xref="PDB:3J3V" /db_xref="PDB:3J3W" /db_xref="PDB:3J9W" /db_xref="PDB:5NJT" /db_xref="SubtiList:BG11408" /db_xref="UniProtKB/Swiss-Prot:P46898" /translation="MSRVGKKLLEIPSDVTVTLNDNNTVAVKGPKGELTRTFHPDMEI KVEDNVLTVARPSDQKEHRALHGTTRSLLGNMVEGVSKGFERGLELVGVGYRASKSGN KLVLNVGYSHPVEIVPEEGIEIEVPSQTKVVVKGTDKERVGAIAANIRAVRSPEPYKG KGIRYEGEVVRRKEGKSAK*" gene 142402..142941 /gene="rplF" /locus_tag="BSU_01310" /old_locus_tag="BSU01310" CDS 142974..143336 /gene="rplR" /locus_tag="BSU_01320" /old_locus_tag="BSU01320" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 12682299; Product type s : structure" /codon_start=1 /transl_table=11 /product="ribosomal protein L18" /protein_id="NP_388013.2" /db_xref="EnsemblGenomes-Gn:BSU01320" /db_xref="EnsemblGenomes-Tr:CAB11908" /db_xref="GOA:P46899" /db_xref="InterPro:IPR004389" /db_xref="InterPro:IPR005484" /db_xref="PDB:3J3V" /db_xref="PDB:3J9W" /db_xref="PDB:5NJT" /db_xref="SubtiList:BG11409" /db_xref="UniProtKB/Swiss-Prot:P46899" /translation="MITKTSKNAARLKRHARVRAKLSGTAERPRLNVFRSNKHIYAQI IDDVNGVTLASASTLDKDLNVESTGDTSAATKVGELVAKRAAEKGISDVVFDRGGYLY HGRVKALADAAREAGLKF*" gene 142974..143336 /gene="rplR" /locus_tag="BSU_01320" /old_locus_tag="BSU01320" CDS 143361..143861 /gene="rpsE" /locus_tag="BSU_01330" /old_locus_tag="BSU01330" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:6211592, 12682299" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 6211592, 12682299; Product type s: structure" /codon_start=1 /transl_table=11 /product="ribosomal protein S5" /protein_id="NP_388014.1" /db_xref="EnsemblGenomes-Gn:BSU01330" /db_xref="EnsemblGenomes-Tr:CAB11909" /db_xref="GOA:P21467" /db_xref="InterPro:IPR000851" /db_xref="InterPro:IPR005324" /db_xref="InterPro:IPR005712" /db_xref="InterPro:IPR013810" /db_xref="InterPro:IPR014721" /db_xref="InterPro:IPR018192" /db_xref="InterPro:IPR020568" /db_xref="PDB:3J9W" /db_xref="PDB:5NJT" /db_xref="SubtiList:BG10442" /db_xref="UniProtKB/Swiss-Prot:P21467" /translation="MRRIDPSKLELEERLVTVNRVAKVVKGGRRFRFAALVVVGDKNG HVGFGTGKAQEVPEAIRKAVEDAKKNLIEVPMVGTTIPHEIIGRFGAGNILLKPASEG TGVIAGGPVRAVLELAGVADILSKSLGSNTPINMIRATLQGLSELKRAEDVAKLRGKS VEELLG*" gene 143361..143861 /gene="rpsE" /locus_tag="BSU_01330" /old_locus_tag="BSU01330" CDS 143875..144054 /gene="rpmD" /locus_tag="BSU_01340" /old_locus_tag="BSU01340" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 12682299; Product type s : structure" /codon_start=1 /transl_table=11 /product="ribosomal protein L30 (BL27)" /protein_id="NP_388015.1" /db_xref="EnsemblGenomes-Gn:BSU01340" /db_xref="EnsemblGenomes-Tr:CAB11910" /db_xref="GOA:P19947" /db_xref="InterPro:IPR005996" /db_xref="InterPro:IPR016082" /db_xref="InterPro:IPR018038" /db_xref="InterPro:IPR036919" /db_xref="PDB:3J3V" /db_xref="PDB:3J9W" /db_xref="PDB:5NJT" /db_xref="SubtiList:BG10443" /db_xref="UniProtKB/Swiss-Prot:P19947" /translation="MAKLEITLKRSVIGRPEDQRVTVRTLGLKKTNQTVVHEDNAAIR GMINKVSHLVSVKEQ*" gene 143875..144054 /gene="rpmD" /locus_tag="BSU_01340" /old_locus_tag="BSU01340" CDS 144085..144525 /gene="rplO" /locus_tag="BSU_01350" /old_locus_tag="BSU01350" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:12682299, 15855514, 23002217" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12682299, 15855514, 23002217; Product type s: structure" /codon_start=1 /transl_table=11 /product="ribosomal protein L15" /protein_id="NP_388016.1" /db_xref="EnsemblGenomes-Gn:BSU01350" /db_xref="EnsemblGenomes-Tr:CAB11911" /db_xref="GOA:P19946" /db_xref="InterPro:IPR001196" /db_xref="InterPro:IPR005749" /db_xref="InterPro:IPR021131" /db_xref="InterPro:IPR030878" /db_xref="InterPro:IPR036227" /db_xref="PDB:3J3V" /db_xref="PDB:3J3W" /db_xref="PDB:3J9W" /db_xref="PDB:5NJT" /db_xref="SubtiList:BG10444" /db_xref="UniProtKB/Swiss-Prot:P19946" /translation="MKLHELKPSEGSRKTRNRVGRGIGSGNGKTAGKGHKGQNARSGG GVRPGFEGGQMPLFQRLPKRGFTNINRKEYAVVNLDKLNGFAEGTEVTPELLLETGVI SKLNAGVKILGNGKLEKKLTVKANKFSASAKEAVEAAGGTAEVI*" gene 144085..144525 /gene="rplO" /locus_tag="BSU_01350" /old_locus_tag="BSU01350" CDS 144527..145822 /gene="secY" /locus_tag="BSU_01360" /old_locus_tag="BSU01360" /function="16.1: Circulate" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:9917412, 15341641, 15849754, 16850406, 23852076, 22720735, 27336478" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9917412, 15341641, 15849754, 16850406, 23852076, 22720735, 27336478; Product type t: transporter" /codon_start=1 /transl_table=11 /product="preprotein translocase subunit" /protein_id="NP_388017.1" /db_xref="EnsemblGenomes-Gn:BSU01360" /db_xref="EnsemblGenomes-Tr:CAB11912" /db_xref="GOA:P16336" /db_xref="InterPro:IPR002208" /db_xref="InterPro:IPR023201" /db_xref="InterPro:IPR026593" /db_xref="InterPro:IPR030659" /db_xref="SubtiList:BG10445" /db_xref="UniProtKB/Swiss-Prot:P16336" /translation="MFKTISNFMRVSDIRNKIIFTLLMLIVFRIGAFIPVPYVNAEAL QAQSQMGVFDLLNTFGGGALYQFSIFAMGITPYITASIIIQLLQMDVVPKFTEWSKQG EVGRRKLAQFTRYFTIVLGFIQALGMSYGFNNLANGMLIEKSGVSTYLIIALVLTGGT AFLMWLGEQITSHGVGNGISIIIFAGIVSSIPKTIGQIYETQFVGSNDQLFIHIVKVA LLVIAILAVIVGVIFIQQAVRKIAIQYAKGTGRSPAGGGQSTHLPLKVNPAGVIPVIF AVAFLITPRTIASFFGTNDVTKWIQNNFDNTHPVGMAIYVALIIAFTYFYAFVQVNPE QMADNLKKQGGYIPGVRPGKMTQDRITSILYRLTFVGSIFLAVISILPIFFIQFAGLP QSAQIGGTSLLIVVGVALETMKQLESQLVKRNYRGFMKN*" gene 144527..145822 /gene="secY" /locus_tag="BSU_01360" /old_locus_tag="BSU01360" CDS 145877..146530 /gene="adk" /locus_tag="BSU_01370" /old_locus_tag="BSU01370" /EC_number="2.7.4.3" /function="16.2: Construct biomass (Anabolism)" /function="16.7: Manage energy" /experiment="publication(s) with functional evidences, PMID:8061005, 8288548, 9056261, 9715904, 11106368, 16452168" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8061005, 8288548, 9056261, 9715904, 11106368, 16452168; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="adenylate kinase" /protein_id="NP_388018.1" /db_xref="EnsemblGenomes-Gn:BSU01370" /db_xref="EnsemblGenomes-Tr:CAB11913" /db_xref="GOA:P16304" /db_xref="InterPro:IPR000850" /db_xref="InterPro:IPR006259" /db_xref="InterPro:IPR007862" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR033690" /db_xref="PDB:1P3J" /db_xref="PDB:2EU8" /db_xref="PDB:2OO7" /db_xref="PDB:2ORI" /db_xref="PDB:2OSB" /db_xref="PDB:2P3S" /db_xref="PDB:2QAJ" /db_xref="PDB:3DKV" /db_xref="PDB:3DL0" /db_xref="PDB:4MKF" /db_xref="PDB:4MKG" /db_xref="PDB:4MKH" /db_xref="PDB:4QBF" /db_xref="PDB:4QBG" /db_xref="PDB:4TYP" /db_xref="PDB:4TYQ" /db_xref="SubtiList:BG10446" /db_xref="UniProtKB/Swiss-Prot:P16304" /translation="MNLVLMGLPGAGKGTQGERIVEDYGIPHISTGDMFRAAMKEETP LGLEAKSYIDKGELVPDEVTIGIVKERLGKDDCERGFLLDGFPRTVAQAEALEEILEE YGKPIDYVINIEVDKDVLMERLTGRRICSVCGTTYHLVFNPPKTPGICDKDGGELYQR ADDNEETVSKRLEVNMKQTQPLLDFYSEKGYLANVNGQQDIQDVYADVKDLLGGLKK* " gene 145877..146530 /gene="adk" /locus_tag="BSU_01370" /old_locus_tag="BSU01370" CDS 146527..147273 /gene="mapA" /locus_tag="BSU_01380" /old_locus_tag="BSU01380" /EC_number="3.4.11.18" /function="16.11: Scavenge (Catabolism)" /function="16.6: Maintain" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:16207374, 22720735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16207374, 22720735; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="methionine aminopeptidase" /protein_id="NP_388019.1" /db_xref="EnsemblGenomes-Gn:BSU01380" /db_xref="EnsemblGenomes-Tr:CAB11914" /db_xref="GOA:P19994" /db_xref="InterPro:IPR000994" /db_xref="InterPro:IPR001714" /db_xref="InterPro:IPR002467" /db_xref="InterPro:IPR036005" /db_xref="SubtiList:BG10447" /db_xref="UniProtKB/Swiss-Prot:P19994" /translation="MIICKTPRELGIMREAGRIVALTHEELKKHIKPGISTKELDQIA ERFIKKQGAIPSFKGYNGFRGSICVSVNEELVHGIPGSRVLKDGDIISIDIGAKLNGY HGDSAWTYPVGNISDDDKKLLEVTEESLYKGLQEAKPGERLSNISHAIQTYVENEQFS VVREYVGHGVGQDLHEDPQIPHYGPPNKGPRLKPGMVLAIEPMVNAGSRYVKTLADNW TVVTVDGKKCAHFEHTIAITETGFDILTRV*" gene 146527..147273 /gene="mapA" /locus_tag="BSU_01380" /old_locus_tag="BSU01380" CDS 147312..147536 /gene="ybzG" /locus_tag="BSU_01389" /old_locus_tag="BSU01389" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 17157877; Product type f: factor" /codon_start=1 /transl_table=11 /product="putative ribosome binding protein" /protein_id="YP_003097669.1" /db_xref="EnsemblGenomes-Gn:BSU01389" /db_xref="EnsemblGenomes-Tr:CAX52539" /db_xref="UniProtKB/Swiss-Prot:C0H3S8" /translation="MIGQKAWVNIGKTEFILLLVVGILTIINVLTADGEKRTFHSPKK KNINHLTLYDCVSPEVQNSINETGRVTNFF*" gene 147312..147536 /gene="ybzG" /locus_tag="BSU_01389" /old_locus_tag="BSU01389" CDS 147585..147803 /gene="infA" /locus_tag="BSU_01390" /old_locus_tag="BSU01390" /function="16.3: Control" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 9868784, 20477873, 22720735; Product type f: factor" /codon_start=1 /transl_table=11 /product="initiation factor IF-I" /protein_id="NP_388020.1" /db_xref="EnsemblGenomes-Gn:BSU01390" /db_xref="EnsemblGenomes-Tr:CAB11915" /db_xref="GOA:P20458" /db_xref="InterPro:IPR004368" /db_xref="InterPro:IPR006196" /db_xref="InterPro:IPR012340" /db_xref="InterPro:IPR022967" /db_xref="SubtiList:BG11043" /db_xref="UniProtKB/Swiss-Prot:P20458" /translation="MAKDDVIEVEGTIVETLPNAMFKVELENGHTVLAHVSGKIRMHF IRILPGDKVTVELSPYDLTRGRITYRYK*" gene 147585..147803 /gene="infA" /locus_tag="BSU_01390" /old_locus_tag="BSU01390" CDS 147837..147950 /gene="rpmJ" /locus_tag="BSU_01400" /old_locus_tag="BSU01400" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:1783905, 23002217, 24335279" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1783905, 23002217, 24335279; Product type f: factor" /codon_start=1 /transl_table=11 /product="ribosomal protein L36 (ribosomal protein B)" /protein_id="NP_388021.1" /db_xref="EnsemblGenomes-Gn:BSU01400" /db_xref="EnsemblGenomes-Tr:CAB11916" /db_xref="GOA:P20278" /db_xref="InterPro:IPR000473" /db_xref="InterPro:IPR035977" /db_xref="PDB:3J9W" /db_xref="PDB:5NJT" /db_xref="SubtiList:BG11042" /db_xref="UniProtKB/Swiss-Prot:P20278" /translation="MKVRPSVKPICEKCKVIRRKGKVMVICENPKHKQKQG*" gene 147837..147950 /gene="rpmJ" /locus_tag="BSU_01400" /old_locus_tag="BSU01400" CDS 147973..148338 /gene="rpsM" /locus_tag="BSU_01410" /old_locus_tag="BSU01410" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 12682299, 22720735; Product type s: structure" /codon_start=1 /transl_table=11 /product="ribosomal protein S13" /protein_id="NP_388022.2" /db_xref="EnsemblGenomes-Gn:BSU01410" /db_xref="EnsemblGenomes-Tr:CAB11917" /db_xref="GOA:P20282" /db_xref="InterPro:IPR001892" /db_xref="InterPro:IPR010979" /db_xref="InterPro:IPR018269" /db_xref="InterPro:IPR019980" /db_xref="InterPro:IPR027437" /db_xref="PDB:3J9W" /db_xref="PDB:5NJT" /db_xref="SubtiList:BG10730" /db_xref="UniProtKB/Swiss-Prot:P20282" /translation="MARIAGVDIPRDKRVVISLTYIFGIGRTTAQQVLKEAGVSEDTR VRDLTEEELGKIRDIIDKLKVEGDLRREVSLNIKRLIEIGSYRGIRHRRGLPVRGQNS KNNARTRKGPRRTVANKKK*" gene 147973..148338 /gene="rpsM" /locus_tag="BSU_01410" /old_locus_tag="BSU01410" CDS 148359..148754 /gene="rpsK" /locus_tag="BSU_01420" /old_locus_tag="BSU01420" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:10217780, 12682299, 22720735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10217780, 12682299, 22720735; Product type s: structure" /codon_start=1 /transl_table=11 /product="ribosomal protein S11 (BS11)" /protein_id="NP_388023.1" /db_xref="EnsemblGenomes-Gn:BSU01420" /db_xref="EnsemblGenomes-Tr:CAB11918" /db_xref="GOA:P04969" /db_xref="InterPro:IPR001971" /db_xref="InterPro:IPR018102" /db_xref="InterPro:IPR019981" /db_xref="InterPro:IPR036967" /db_xref="PDB:3J9W" /db_xref="PDB:5NJT" /db_xref="SubtiList:BG10731" /db_xref="UniProtKB/Swiss-Prot:P04969" /translation="MAAARKSNTRKRRVKKNIESGIAHIRSTFNNTIVTITDTHGNAI SWSSAGALGFRGSRKSTPFAAQMAAETAAKGSIEHGLKTLEVTVKGPGSGREAAIRAL QAAGLEVTAIRDVTPVPHNGCRPPKRRRV*" gene 148359..148754 /gene="rpsK" /locus_tag="BSU_01420" /old_locus_tag="BSU01420" S_feature 148755..148930 /Source="Nicolas_S_feature" /locus_tag="new_148755_148930" /HighExp="G135, dia5, Lbexp, S0, aero, dia0, T-4.40H, G150, Paraq, C30" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="SigA, SigA, SigA, SigA, SigA, SigA, SigWXY, SigA, SigA" /TUlongPSig="1, 1, 0.997, 1, 1, 0.999, 1, 1, 0.947" /label="S56" CDS 148931..149875 /gene="rpoA" /locus_tag="BSU_01430" /old_locus_tag="BSU01430" /EC_number="2.7.7.6" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:1484484, 6811591, 9594570, 10972808, 12682299, 22720735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1484484, 6811591, 9594570, 10972808, 12682299, 22720735; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="RNA polymerase (alpha subunit)" /protein_id="NP_388024.1" /db_xref="EnsemblGenomes-Gn:BSU01430" /db_xref="EnsemblGenomes-Tr:CAB11919" /db_xref="GOA:P20429" /db_xref="InterPro:IPR011260" /db_xref="InterPro:IPR011262" /db_xref="InterPro:IPR011263" /db_xref="InterPro:IPR011773" /db_xref="InterPro:IPR036603" /db_xref="InterPro:IPR036643" /db_xref="PDB:1Z3E" /db_xref="PDB:3GFK" /db_xref="PDB:3IHQ" /db_xref="SubtiList:BG10732" /db_xref="UniProtKB/Swiss-Prot:P20429" /translation="MIEIEKPKIETVEISDDAKFGKFVVEPLERGYGTTLGNSLRRIL LSSLPGAAVTSIQIDGVLHEFSTIEGVVEDVTTIILHIKKLALKIYSDEEKTLEIDVQ GEGTVTAADITHDSDVEILNPDLHIATLGENASFRVRLTAQRGRGYTPADANKRDDQP IGVIPIDSIYTPVSRVSYQVENTRVGQVANYDKLTLDVWTDGSTGPKEAIALGSKILT EHLNIFVGLTDEAQHAEIMVEKEEDQKEKVLEMTIEELDLSVRSYNCLKRAGINTVQE LANKTEEDMMKVRNLGRKSLEEVKAKLEELGLGLRKDD*" gene 148931..149875 /gene="rpoA" /locus_tag="BSU_01430" /old_locus_tag="BSU01430" CDS 149953..150315 /gene="rplQ" /locus_tag="BSU_01440" /old_locus_tag="BSU01440" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:6801428, 10717392, 12682299" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 6801428, 10717392, 12682299; Product type s: structure" /codon_start=1 /transl_table=11 /product="ribosomal protein L17 (BL15)" /protein_id="NP_388025.1" /db_xref="EnsemblGenomes-Gn:BSU01440" /db_xref="EnsemblGenomes-Tr:CAB11920" /db_xref="GOA:P20277" /db_xref="InterPro:IPR000456" /db_xref="InterPro:IPR036373" /db_xref="PDB:3J3V" /db_xref="PDB:3J3W" /db_xref="PDB:3J9W" /db_xref="PDB:5NJT" /db_xref="SubtiList:BG11041" /db_xref="UniProtKB/Swiss-Prot:P20277" /translation="MSYRKLGRTSAQRKAMLRDLTTDLIINERIETTETRAKELRSVV EKMITLGKRGDLHARRQAAAYIRNEVANEENNQDALQKLFSDIATRYEERQGGYTRIM KLGPRRGDGAPMAIIELV*" gene 149953..150315 /gene="rplQ" /locus_tag="BSU_01440" /old_locus_tag="BSU01440" downshifts 150317 /Source="Nicolas_upshifts" /id="D52" /incds=0 /nref=171 /ntot=259 /MaxReadThrough="7.50771" /MaxDrop="5.4374" /score="2.32634618" /energy="-10.5" /TU="U98" /idTUdmin="U98" /TUdmin="-5577" /isTUend="FALSE" S_feature 150362..150442 /Source="Nicolas_S_feature" /locus_tag="new_150362_150442" /HighExp="Cold, G180, G135, G150, H2O2, S0, C30, Oxctl, Paraq, Lbexp" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="SigA, SigA, SigA, SigA, SigA, SigA, SigWXY, SigA, SigA" /TUlongPSig="1, 1, 0.997, 1, 1, 0.999, 1, 1, 0.947" /label="S57" CDS 150443..151288 /gene="ecfA" /locus_tag="BSU_01450" /old_locus_tag="BSU01450" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 12110480, 21135102, 26052893; Product type t: transporter" /codon_start=1 /transl_table=11 /product="energizing coupling factor of ABC influx transporter (ATP-binding protein)" /protein_id="NP_388026.2" /db_xref="EnsemblGenomes-Gn:BSU01450" /db_xref="EnsemblGenomes-Tr:CAB11921" /db_xref="GOA:P40735" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR015856" /db_xref="InterPro:IPR017871" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR030947" /db_xref="SubtiList:BG11067" /db_xref="UniProtKB/Swiss-Prot:P40735" /translation="MNQNQLISVEDIVFRYRKDAERRALDGVSLQVYEGEWLAIVGHN GSGKSTLARALNGLILPESGDIEVAGIQLTEESVWEVRKKIGMVFQNPDNQFVGTTVR DDVAFGLENNGVPREEMIERVDWAVKQVNMQDFLDQEPHHLSGGQKQRVAIAGVIAAR PDIIILDEATSMLDPIGREEVLETVRHLKEQGMATVISITHDLNEAAKADRIIVMNGG KKYAEGPPEEIFKLNKELVRIGLDLPFSFQLSQLLRENGLALEENHLTQEGLVKELWT LQSKM*" gene 150443..151288 /gene="ecfA" /locus_tag="BSU_01450" /old_locus_tag="BSU01450" CDS 151303..152133 /gene="ecfAB" /locus_tag="BSU_01460" /old_locus_tag="BSU01460" /function="16.1: Circulate" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:12110480, 21135102, 26052893" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12110480, 21135102, 26052893; Product type t: transporter" /codon_start=1 /transl_table=11 /product="energizing coupling factor of ABC influx transporter (ATP-binding protein)" /protein_id="NP_388027.1" /db_xref="EnsemblGenomes-Gn:BSU01460" /db_xref="EnsemblGenomes-Tr:CAB11922" /db_xref="GOA:P70970" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR015856" /db_xref="InterPro:IPR017871" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR030946" /db_xref="SubtiList:BG11989" /db_xref="UniProtKB/Swiss-Prot:P70970" /translation="MKTPFERLALYDINASIKEGSYVAVIGHTGSGKSTLLQHLNGLL KPTKGQISLGSTVIQAGKKNKDLKKLRKKVGIVFQFPEHQLFEETVLKDISFGPMNFG VKKEDAEQKAREMLQLVGLSEELLDRSPFELSGGQMRRVAIAGVLAMDPEVLVLDEPT AGLDPRGRKEIMDMFYELHQRGNLTTILVTHSMEDAAAYADEMIVMHKGTIQASGSPR DLFLKGEEMAGWGLDLPETIKFQRHLEAALGVRFNEPMLTIEDAAAEIRALFQGEKTL *" gene 151303..152133 /gene="ecfAB" /locus_tag="BSU_01460" /old_locus_tag="BSU01460" CDS 152130..152927 /gene="ecfT" /locus_tag="BSU_01470" /old_locus_tag="BSU01470" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 15849754, 16850406, 18931129, 21135102, 26052893; Product type t : transporter" /codon_start=1 /transl_table=11 /product="component of the influx ECF transporters" /protein_id="NP_388028.2" /db_xref="EnsemblGenomes-Gn:BSU01470" /db_xref="EnsemblGenomes-Tr:CAB11923" /db_xref="GOA:P70972" /db_xref="InterPro:IPR003339" /db_xref="InterPro:IPR024919" /db_xref="SubtiList:BG11990" /db_xref="UniProtKB/Swiss-Prot:P70972" /translation="MMDSMIIGKYVPGTSLVHRLDPRTKLITIFLFVCIVFLANNVQT YALLGLFTIGVVSLTRVPFSFLMKGLKPIIWIVLFTFLLHILMTHEGPIIFQIGFFKV YEGGLVQGIFISLRFVYLILITTLLTLTTTPIEITDGMEQLLNPLKKLKLPVHELALM MSISLRFIPTLMEETDKIMKAQMARGVDFTSGPVKERVKAIVPLLVPLFVSAFKRAEE LAVAMEARGYQGGEGRTKYRKLVWTGKDTSVIVSLIVLAALLFFLRA*" gene 152130..152927 /gene="ecfT" /locus_tag="BSU_01470" /old_locus_tag="BSU01470" CDS 152937..153680 /gene="truA" /locus_tag="BSU_01480" /old_locus_tag="BSU01480" /EC_number="5.4.99.12" /function="16.6: Maintain" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 10529181, 15353568, 17114947, 17466622; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="tRNA pseudouridine (38-40) synthase" /protein_id="NP_388029.2" /db_xref="EnsemblGenomes-Gn:BSU01480" /db_xref="EnsemblGenomes-Tr:CAB11924" /db_xref="GOA:P70973" /db_xref="InterPro:IPR001406" /db_xref="InterPro:IPR020095" /db_xref="InterPro:IPR020097" /db_xref="InterPro:IPR020103" /db_xref="SubtiList:BG11992" /db_xref="UniProtKB/Swiss-Prot:P70973" /translation="MRLKCTISYDGHLFNGYQVQPGKRTVQDELEKALAVLHKSKDRI PVVSSGRTDSGVHAAGQVIHFDTPLSIPAERWPYALNALLPDDIAVKQAEIADDGFHA RFSAVKKEYRYFVYTEKHPDVFKRHYAYHFSYRLNVQDMREAAKHLIGTHDFTSFCAA KTEVQDKVRTIYELDWTETADGLQMRITGSGFLYNMVRIIAGTLLDAGIGKISPDEVK SMLEAKDREAAGRTAPGHGLYLWNVYYDN*" gene 152937..153680 /gene="truA" /locus_tag="BSU_01480" /old_locus_tag="BSU01480" S_feature complement(153039..153507) /Source="Nicolas_S_feature" /locus_tag="new_153039_153507_c" /HighExp="S6, S8, S7, C30, G135, BT, S5, C90, M/G, Pyr" /AntisenseName="truA" /AntisenseCor="-0.30232258010971202" /AntisenseRegPval="-6.4" /CDS_PredictionProba="NA" /TUshortSig="SigK" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S58" promotor_-35 153172..153177 /Source="Nicolas_upshift_promotors" /id="U100" /multdbtbs="-" /comp="M10" /sig="Sig-" /pcomp="0.478521478521479" /psig="0.478521478521479" /xcortree=2469 /SigmaFactorBS="cggctgagagatggccatatgCCTTAAatgcactgcttccgG ACGATATCGCAGTCAAAcaggcagaaattgcggatgatgggttccatgcacgatttag c" /listShort="NA, rplM, rpsI, S59, ybaJ" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 153192..153209 /Source="Nicolas_upshift_promotors" /id="U100" /multdbtbs="-" /comp="M10" /sig="Sig-" /pcomp="0.478521478521479" /psig="0.478521478521479" /xcortree=2469 /SigmaFactorBS="cggctgagagatggccatatgCCTTAAatgcactgcttccgG ACGATATCGCAGTCAAAcaggcagaaattgcggatgatgggttccatgcacgatttag c" /listShort="NA, rplM, rpsI, S59, ybaJ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 153211 /Source="Nicolas_upshifts" /id="U100" /multdbtbs="-" /comp="M10" /sig="Sig-" /pcomp="0.478521478521479" /psig="0.478521478521479" /xcortree=2469 /SigmaFactorBS="cggctgagagatggccatatgCCTTAAatgcactgcttccgG ACGATATCGCAGTCAAAcaggcagaaattgcggatgatgggttccatgcacgatttag c" /listShort="NA, rplM, rpsI, S59, ybaJ" /GFF_Attribute="listLong" promotor_-10 complement(153507..153526) /Source="Nicolas_upshift_promotors" /id="U101" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1250 /SigmaFactorBS="ttcacctcatcgggagaaatttttccaatacctgcatcaagC AAAGTACCCgcaataattctgACCATATTATATAAGAAACCgctgcctgtgatccgca t" /listShort="S58" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(153529) /Source="Nicolas_upshifts" /id="U101" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1250 /SigmaFactorBS="ttcacctcatcgggagaaatttttccaatacctgcatcaagC AAAGTACCCgcaataattctgACCATATTATATAAGAAACCgctgcctgtgatccgca t" /listShort="S58" /GFF_Attribute="listLong" promotor_-35 complement(153539..153548) /Source="Nicolas_upshift_promotors" /id="U101" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1250 /SigmaFactorBS="ttcacctcatcgggagaaatttttccaatacctgcatcaagC AAAGTACCCgcaataattctgACCATATTATATAAGAAACCgctgcctgtgatccgca t" /listShort="S58" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 153700..153706 /Source="Nicolas_upshift_promotors" /id="U102" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.754245754245754" /psig=1 /xcortree=2644 /SigmaFactorBS="ttactatgacaactaaaccaggtgtataatattttCTTGACA gagtctgcataaagTTATAAGATATCATATGGTAtgtatttcaaccccacgataagcc c" /listShort="NA, rplM, rpsI, S59, ybaJ" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 153721..153740 /Source="Nicolas_upshift_promotors" /id="U102" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.754245754245754" /psig=1 /xcortree=2644 /SigmaFactorBS="ttactatgacaactaaaccaggtgtataatattttCTTGACA gagtctgcataaagTTATAAGATATCATATGGTAtgtatttcaaccccacgataagcc c" /listShort="NA, rplM, rpsI, S59, ybaJ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 153725 /Source="Nicolas_upshifts" /id="U102" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.754245754245754" /psig=1 /xcortree=2644 /SigmaFactorBS="ttactatgacaactaaaccaggtgtataatattttCTTGACA gagtctgcataaagTTATAAGATATCATATGGTAtgtatttcaaccccacgataagcc c" /listShort="NA, rplM, rpsI, S59, ybaJ" /GFF_Attribute="listLong" misc_RNA 153737..153793 /gene="ldlM" /locus_tag="BSU_misc_RNA_4" /product="putative L13_leader" /note="Evidence 3: Putative function from multiple computational evidences; Product type n: RNA" gene 153737..153793 /gene="ldlM" /locus_tag="BSU_misc_RNA_4" CDS 153842..154279 /gene="rplM" /locus_tag="BSU_01490" /old_locus_tag="BSU01490" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:10781545, 12682299, 23504016, 22720735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10781545, 12682299, 23504016, 22720735; Product type s: structure" /codon_start=1 /transl_table=11 /product="ribosomal protein L13" /protein_id="NP_388030.2" /db_xref="EnsemblGenomes-Gn:BSU01490" /db_xref="EnsemblGenomes-Tr:CAB11925" /db_xref="GOA:P70974" /db_xref="InterPro:IPR005822" /db_xref="InterPro:IPR005823" /db_xref="InterPro:IPR023563" /db_xref="InterPro:IPR036899" /db_xref="PDB:3J3V" /db_xref="PDB:3J3W" /db_xref="PDB:3J9W" /db_xref="PDB:5NJT" /db_xref="SubtiList:BG11970" /db_xref="UniProtKB/Swiss-Prot:P70974" /translation="MRTTPMANASTIERKWLVVDAAGKTLGRLSSEVAAILRGKHKPT YTPHVDTGDHVIIINAEKIELTGKKLTDKIYYRHTQHPGGLKSRTALEMRTNYPEKML ELAIKGMLPKGSLGRQMFKKLNVYRGSEHPHEAQKPEVYELRG*" gene 153842..154279 /gene="rplM" /locus_tag="BSU_01490" /old_locus_tag="BSU01490" CDS 154300..154692 /gene="rpsI" /locus_tag="BSU_01500" /old_locus_tag="BSU01500" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 12682299, 19653700, 22720735; Product type s: structure" /codon_start=1 /transl_table=11 /product="ribosomal protein S9" /protein_id="NP_388031.1" /db_xref="EnsemblGenomes-Gn:BSU01500" /db_xref="EnsemblGenomes-Tr:CAB11926" /db_xref="GOA:P21470" /db_xref="InterPro:IPR000754" /db_xref="InterPro:IPR014721" /db_xref="InterPro:IPR020568" /db_xref="InterPro:IPR020574" /db_xref="InterPro:IPR023035" /db_xref="PDB:3J9W" /db_xref="PDB:5NJT" /db_xref="SubtiList:BG19007" /db_xref="UniProtKB/Swiss-Prot:P21470" /translation="MAQVQYYGTGRRKSSVARVRLVPGEGRIVVNNREISEHIPSAAL IEDIKQPLTLTETAGTYDVLVNVHGGGLSGQAGAIRHGIARALLEADPEYRTTLKRAG LLTRDARMKERKKYGLKGARRAPQFSKR*" gene 154300..154692 /gene="rpsI" /locus_tag="BSU_01500" /old_locus_tag="BSU01500" downshifts 154667 /Source="Nicolas_upshifts" /id="D53" /incds=0 /nref=262 /ntot=282 /MaxReadThrough="4.65387" /MaxDrop="8.11906" /score="30.5093496" /energy="-13.3" /TU="U98,U100,U102" /idTUdmin="U98" /TUdmin="-1227" /isTUend="FALSE" promotor_-35 154809..154816 /Source="Nicolas_upshift_promotors" /id="U103" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.97002997002997" /psig="0.999000999001" /xcortree=2051 /SigmaFactorBS="ctgaatggacgcttgacggggttaagcaaatTGTTTGTTtat aaacggtctcTTTGTAATAATCATGGTAGAtttcattcttattcaattggaagttcgg t" /listShort="S59, ybaJ" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 154830..154849 /Source="Nicolas_upshift_promotors" /id="U103" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.97002997002997" /psig="0.999000999001" /xcortree=2051 /SigmaFactorBS="ctgaatggacgcttgacggggttaagcaaatTGTTTGTTtat aaacggtctcTTTGTAATAATCATGGTAGAtttcattcttattcaattggaagttcgg t" /listShort="S59, ybaJ" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 154838..155119 /Source="Nicolas_S_feature" /locus_tag="new_154838_155119" /HighExp="H2O2, G180, G135, Paraq, Diami, dia15, Oxctl, Cold, Heat, G150" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA, Sig-, SigA" /TUshortPSig="0.999, 1, 0.479, 1" /TUlongSig="SigA, SigA, SigA, SigA, SigA, SigA, SigWXY, SigA, SigA" /TUlongPSig="1, 1, 0.997, 1, 1, 0.999, 1, 1, 0.947" /label="S59" upshifts 154838 /Source="Nicolas_upshifts" /id="U103" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.97002997002997" /psig="0.999000999001" /xcortree=2051 /SigmaFactorBS="ctgaatggacgcttgacggggttaagcaaatTGTTTGTTtat aaacggtctcTTTGTAATAATCATGGTAGAtttcattcttattcaattggaagttcgg t" /listShort="S59, ybaJ" /GFF_Attribute="listLong" misc_feature 155118..155137 /Source="Nicolas_upshift_promotors" /id="U104" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.625374625374625" /psig="0.804195804195804" /xcortree=3216 /SigmaFactorBS="gtttttatgaacttttttctaaatatgcaaagggaaagcgat atcaatctagaaataTTTGTTATACTCTATACATTaaagtaaggagaagattcatgaa t" /listShort="ybaJ" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 155121 /Source="Nicolas_upshifts" /id="U104" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.625374625374625" /psig="0.804195804195804" /xcortree=3216 /SigmaFactorBS="gtttttatgaacttttttctaaatatgcaaagggaaagcgat atcaatctagaaataTTTGTTATACTCTATACATTaaagtaaggagaagattcatgaa t" /listShort="ybaJ" /GFF_Attribute="listLong" CDS 155156..155923 /gene="ybaJ" /locus_tag="BSU_01510" /old_locus_tag="BSU01510" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 26582911; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative methyltransferase" /protein_id="NP_388032.2" /db_xref="EnsemblGenomes-Gn:BSU01510" /db_xref="EnsemblGenomes-Tr:CAB11927" /db_xref="GOA:P70976" /db_xref="InterPro:IPR013216" /db_xref="InterPro:IPR029063" /db_xref="SubtiList:BG11994" /db_xref="UniProtKB/Swiss-Prot:P70976" /translation="MNALVAHNSKAWDKKVETGNEWTVAVEQQVIEQAKKGNWDIRVT PMKDVPKDWFPPIKGLKVLCLASGGGQQGPVLAAAGADVTVLDNSEKQLNQDRMIAER DGLTIHTVKGSMDDLSVFNDESFDVIVHPVANVFVENVLPVWKEAYRVLKRNGILISG FVNPVVFLFDTELEQQGVLKVKHSIPYADPEDLPKHKVKKLIENNEALEFGHSLEDQI KGQIDAGFIVTGFYEDKGGFVLDQYIHTYSATRSVKV*" gene 155156..155923 /gene="ybaJ" /locus_tag="BSU_01510" /old_locus_tag="BSU01510" downshifts 155914 /Source="Nicolas_upshifts" /id="D54" /incds=0 /nref=215 /ntot=251 /MaxReadThrough="2.69346" /MaxDrop="6.09641" /score="4.42269359" /energy="-10.3" /TU="NA" /idTUdmin="U100" /TUdmin="-2" /isTUend="TRUE" promotor_-35 156053..156059 /Source="Nicolas_upshift_promotors" /id="U105" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=864 /SigmaFactorBS="ccttcatttgggcgaatttccaaccgaattcgGGCATTGttt catcatccaaaCCTCAAAATAATcggtaaaaggagagtgaatttatatggcagaagta c" /listShort="ybaK, cwlD" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 156074..156085 /Source="Nicolas_upshift_promotors" /id="U105" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=864 /SigmaFactorBS="ccttcatttgggcgaatttccaaccgaattcgGGCATTGttt catcatccaaaCCTCAAAATAATcggtaaaaggagagtgaatttatatggcagaagta c" /listShort="ybaK, cwlD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 156081 /Source="Nicolas_upshifts" /id="U105" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=864 /SigmaFactorBS="ccttcatttgggcgaatttccaaccgaattcgGGCATTGttt catcatccaaaCCTCAAAATAATcggtaaaaggagagtgaatttatatggcagaagta c" /listShort="ybaK, cwlD" /GFF_Attribute="listLong" CDS 156109..156552 /gene="ybaK" /locus_tag="BSU_01520" /old_locus_tag="BSU01520" /function="16.8: Protect" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 14679227, 16267290" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_388033.1" /db_xref="EnsemblGenomes-Gn:BSU01520" /db_xref="EnsemblGenomes-Tr:CAB11928" /db_xref="GOA:P50862" /db_xref="InterPro:IPR019667" /db_xref="SubtiList:BG11503" /db_xref="UniProtKB/Swiss-Prot:P50862" /translation="MAEVLSFMDVKRQKDFELEKNLLKELSLRQIIQSVKDCLEPLFP FLHDERDIITEGCIDFAIEAYLLGGRFGIFGYYGESMQSISARSAREEEELRMEFFDY LYNWIHEQYATFDKNTVYEAARKFIKDWWTAGFVQREKQCKLRMR*" gene 156109..156552 /gene="ybaK" /locus_tag="BSU_01520" /old_locus_tag="BSU01520" promotor_-35 156552..156557 /Source="Nicolas_upshift_promotors" /id="U106" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=973 /SigmaFactorBS="gttcaaagagaaaaacagtgtaagcttcgcatgcggtaATCA TAtttcccgaccctgtcCCATAGTTATGTAATAACGgacaagcgggaggggaagggat g" /listShort="cwlD" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 156573..156591 /Source="Nicolas_upshift_promotors" /id="U106" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=973 /SigmaFactorBS="gttcaaagagaaaaacagtgtaagcttcgcatgcggtaATCA TAtttcccgaccctgtcCCATAGTTATGTAATAACGgacaagcgggaggggaagggat g" /listShort="cwlD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 156574 /Source="Nicolas_upshifts" /id="U106" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=973 /SigmaFactorBS="gttcaaagagaaaaacagtgtaagcttcgcatgcggtaATCA TAtttcccgaccctgtcCCATAGTTATGTAATAACGgacaagcgggaggggaagggat g" /listShort="cwlD" /GFF_Attribute="listLong" CDS 156612..157325 /gene="cwlD" /locus_tag="BSU_01530" /old_locus_tag="BSU01530" /EC_number="3.5.1.28" /function="16.13: Shape" /function="16.8: Protect" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:14679227, 16267290" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 14679227, 16267290; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="N-acetylmuramoyl-L-alanine amidase" /protein_id="NP_388034.1" /db_xref="EnsemblGenomes-Gn:BSU01530" /db_xref="EnsemblGenomes-Tr:CAB11929" /db_xref="GOA:P50864" /db_xref="InterPro:IPR002508" /db_xref="InterPro:IPR014234" /db_xref="SubtiList:BG11514" /db_xref="UniProtKB/Swiss-Prot:P50864" /translation="MRKKLKWLSFLLGFIILLFLFKYQFSNNDSWKPWSLPLSGKIIY LDPGHGGPDGGAVGGKLLEKDVTLEVAFRVRDYLQEQGALVIMTRESDTDLAPEGTKG YSRRKAEDLRQRVKLINHSEAELYISIHLNAIPSQKWSGAQSFYYGKYAENEKVAKYI QDELRRNLENTTRKAKRIHGIYLMQNVTKPGALIEVGFLSNPSEATLLGKPKYQDKVA SSIYKGILRYFTEKGDPPE*" gene 156612..157325 /gene="cwlD" /locus_tag="BSU_01530" /old_locus_tag="BSU01530" upshifts 157370 /Source="Nicolas_upshifts" /id="U107" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.965034965034965" /psig="0.998001998001998" /xcortree=3187 /SigmaFactorBS="agaccctccggagtaatggagggttttcttgtggttctaagc ataagacacccgccatttatgTATGATATAATAATAATTGTaaacgaatacacaaaag g" /listShort="salA, S61, kbaA, S63, S64, rrnI-16S" /GFF_Attribute="listLong" misc_feature 157373..157392 /Source="Nicolas_upshift_promotors" /id="U107" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.965034965034965" /psig="0.998001998001998" /xcortree=3187 /SigmaFactorBS="agaccctccggagtaatggagggttttcttgtggttctaagc ataagacacccgccatttatgTATGATATAATAATAATTGTaaacgaatacacaaaag g" /listShort="salA, S61, kbaA, S63, S64, rrnI-16S" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" CDS 157421..158479 /gene="salA" /locus_tag="BSU_01540" /old_locus_tag="BSU01540" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:11790741, 15126467, 26094643" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11790741, 15126467, 26094643; Product type r: regulator" /codon_start=1 /transl_table=11 /product="phosphorylation-dependent (Y327) transcriptionalregulator" /protein_id="NP_388035.1" /db_xref="EnsemblGenomes-Gn:BSU01540" /db_xref="EnsemblGenomes-Tr:CAB11930" /db_xref="GOA:P50863" /db_xref="InterPro:IPR000808" /db_xref="InterPro:IPR019591" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR033756" /db_xref="InterPro:IPR034904" /db_xref="SubtiList:BG11494" /db_xref="UniProtKB/Swiss-Prot:P50863" /translation="MIREDEVRKLVGEMREPFLQRPLGELDAVKEIKIKPEKRHISVK VALAKTGTAEQMQIQQEIVNVLKGAGAETVGLRFEELPEETVAKFRAPSAEKKTLLNM DNPPVFLAVASGKGGVGKSTVSVNLAISLARLGKKVGLIDADIYGFSVPDMMGITVRP TIEGEKLLPVERFGVKVMSMGFFVEENAPVVWRGPMLGKMLNNFFHEVEWGEVDYIVL DLPPGTGDVALDVHTMLPSCKEIIVSTPHPTAAFVAARAGSMAIKTDHEVVGVIENMA YYESAKTGEREYVFGKGGGDKLAEELNVPLLGRIPLKQPDWDKDQFAPSVYDENHPIG EIYQDIAKKIDAKMSVQV*" gene 157421..158479 /gene="salA" /locus_tag="BSU_01540" /old_locus_tag="BSU01540" S_feature complement(158050..158514) /Source="Nicolas_S_feature" /locus_tag="new_158050_158514_c" /HighExp="S8, S7, S6, S5, C30, S4, C90, nit, ferm, Gly" /AntisenseName="salA" /AntisenseCor="-0.104183954485248" /AntisenseRegPval="-1.1000000000000001" /CDS_PredictionProba="NA" /TUshortSig="SigGF" /TUshortPSig="0.996" /TUlongSig="NA" /TUlongPSig="NA" /label="S60" downshifts 158465 /Source="Nicolas_upshifts" /id="D55" /incds=0 /nref=29 /ntot=155 /MaxReadThrough="5.44939" /MaxDrop="4.18382" /score="-4.46878413" /energy="-9.1" /TU="U107" /idTUdmin="U106" /TUdmin=1185 /isTUend="FALSE" S_feature 158510..159181 /Source="Nicolas_S_feature" /locus_tag="new_158510_159181" /HighExp="Lbtran, H2O2, Cold, Lbstat, dia5, M40t45, M0t90, M40t90, T0.30H, S1" /AntisenseName="gerD" /AntisenseCor="-0.24235509346425901" /AntisenseRegPval="-4.2" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.998" /TUlongSig="NA" /TUlongPSig="NA" /label="S61" CDS complement(158515..159072) /gene="gerD" /locus_tag="BSU_01550" /old_locus_tag="BSU01550" /function="16.13: Shape" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:17122337, 10618233, 10376819, 24530795" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 17122337, 10618233, 10376819, 24530795; Product type f: factor" /codon_start=1 /transl_table=11 /product="lipoprotein factor mediating clustering of germination proteins" /protein_id="NP_388036.1" /db_xref="EnsemblGenomes-Gn:BSU01550" /db_xref="EnsemblGenomes-Tr:CAB11931" /db_xref="GOA:P16450" /db_xref="SubtiList:BG10644" /db_xref="UniProtKB/Swiss-Prot:P16450" /translation="MSKAKTLLMSCFLLLSVTACAPKDQAADMDYDQTKKMVVDILKT DDGKKAIKELLNDDAMNEALVIDQDAIKGTIEKTLTSKKGEEFWKNIFEDTDFAEGFA KTLQTEHEKVIKKLMKDPDYQKMLMSVMQDPGMDKKYSQLAKSQEFRSYLEEVINETL SSPLYKKQFEDELKKAAKDTAKESE*" gene complement(158515..159072) /gene="gerD" /locus_tag="BSU_01550" /old_locus_tag="BSU01550" promotor_-10 complement(159104..159115) /Source="Nicolas_upshift_promotors" /id="U108" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp="0.996003996003996" /psig="0.996003996003996" /xcortree=925 /SigmaFactorBS="tattcatcccctcaaaaatcgcgaacagcgatattttgttaT GTATAAttccaaacagatgAATCATATTAAAggtaagacaagtatgtgaaaggagctt a" /listShort="gerD, S60" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(159116) /Source="Nicolas_upshifts" /id="U108" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp="0.996003996003996" /psig="0.996003996003996" /xcortree=925 /SigmaFactorBS="tattcatcccctcaaaaatcgcgaacagcgatattttgttaT GTATAAttccaaacagatgAATCATATTAAAggtaagacaagtatgtgaaaggagctt a" /listShort="gerD, S60" /GFF_Attribute="listLong" promotor_-35 complement(159129..159135) /Source="Nicolas_upshift_promotors" /id="U108" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp="0.996003996003996" /psig="0.996003996003996" /xcortree=925 /SigmaFactorBS="tattcatcccctcaaaaatcgcgaacagcgatattttgttaT GTATAAttccaaacagatgAATCATATTAAAggtaagacaagtatgtgaaaggagctt a" /listShort="gerD, S60" /GFF_Attribute="listLong" /label="promotor_-35" S_feature complement(159149..159778) /Source="Nicolas_S_feature" /locus_tag="new_159149_159778_c" /HighExp="S3, T5.0H, S4, S8, M9-stat, T4.0H, T3.30H, S7, T3.0H, S6" /AntisenseName="kbaA" /AntisenseCor="7.9344921760152495E-2" /AntisenseRegPval="-0.7" /CDS_PredictionProba="NA" /TUshortSig="SigEF" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S62" CDS 159182..159778 /gene="kbaA" /locus_tag="BSU_01560" /old_locus_tag="BSU01560" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:8576055, 15849754, 16850406" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8576055, 15849754, 16850406; Product type r: regulator" /codon_start=1 /transl_table=11 /product="inner membrane protein involved in activation ofthe KinB signaling pathway to sporulation" /protein_id="NP_388037.1" /db_xref="EnsemblGenomes-Gn:BSU01560" /db_xref="EnsemblGenomes-Tr:CAB11932" /db_xref="GOA:P16449" /db_xref="InterPro:IPR024164" /db_xref="SubtiList:BG10643" /db_xref="UniProtKB/Swiss-Prot:P16449" /translation="MKSRGLVRFFFSILAVGALITSIVGFALKWGEYRGLFLTFEAGQ IFSVLFWFIGVGMIFSVISQMGFFVFLTVHRFALEILRSSSLWNLLQLFFILFVAFDL MYVRFLFFGESGESLAGYAWLPVFLLIFGVITAYIKQKQSSKKTFVSSLFLMVVITAL EWFPALRVNDEDWLYLMLFPLMACNAFQLLMLPKFAAK*" gene 159182..159778 /gene="kbaA" /locus_tag="BSU_01560" /old_locus_tag="BSU01560" S_feature 159779..160673 /Source="Nicolas_S_feature" /locus_tag="new_159779_160673" /HighExp="Lbstat, Lbtran, M0t90, M40t90, H2O2, BC, Glucon, S7, M40t45, S1" /AntisenseName="ybaN" /AntisenseCor="-2.6735901031407501E-2" /AntisenseRegPval="-0.2" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.998" /TUlongSig="NA" /TUlongPSig="NA" /label="S63" CDS complement(159779..160543) /gene="pdaB" /locus_tag="BSU_01570" /old_locus_tag="BSU01570" /function="16.8: Protect" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:12662922, 15547282, 15598884" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12662922, 15547282, 15598884; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="polysaccharide deacetylase involved in sporulation" /protein_id="NP_388038.1" /db_xref="EnsemblGenomes-Gn:BSU01570" /db_xref="EnsemblGenomes-Tr:CAB11933" /db_xref="GOA:P50865" /db_xref="InterPro:IPR002509" /db_xref="InterPro:IPR011330" /db_xref="InterPro:IPR014132" /db_xref="SubtiList:BG11416" /db_xref="UniProtKB/Swiss-Prot:P50865" /translation="MNHFYVWHIKRVKQLIIILIAAFAAASFFYIQRAVPLPVFSTDT GPKAIYKGETDSKDISLTFDISWGDERAEPILNTLKANGIKNATFFLSASWAERHPDT VARIVKDGHQIGSMGYAYKNYANLESSEIKKDMNRAQTAFEKLGVKDIQLLRPPTGQF NKNVLKVAKQYNYTVVHYSVNSQDWTNPGVEKIIDNVTKQVSGGDIILLHASDSAKQT EEALPDIIHQLKEKGLKNVTVGDLIANSDAKSAEVK*" gene complement(159779..160543) /gene="pdaB" /locus_tag="BSU_01570" /old_locus_tag="BSU01570" promotor_-10 complement(160574..160592) /Source="Nicolas_upshift_promotors" /id="U109" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=979 /SigmaFactorBS="caacacccaatttaggctgtatgtgaagagacattttatcgG TTATAttcaattgtccatgcTCATAAGATGTAAAACAAGaatgatggacaagataagg a" /listShort="ybaN, S62" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(160594) /Source="Nicolas_upshifts" /id="U109" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=979 /SigmaFactorBS="caacacccaatttaggctgtatgtgaagagacattttatcgG TTATAttcaattgtccatgcTCATAAGATGTAAAACAAGaatgatggacaagataagg a" /listShort="ybaN, S62" /GFF_Attribute="listLong" promotor_-35 complement(160608..160613) /Source="Nicolas_upshift_promotors" /id="U109" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=979 /SigmaFactorBS="caacacccaatttaggctgtatgtgaagagacattttatcgG TTATAttcaattgtccatgcTCATAAGATGTAAAACAAGaatgatggacaagataagg a" /listShort="ybaN, S62" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 160651..160658 /Source="Nicolas_upshift_promotors" /id="U110" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp=1 /psig=1 /xcortree=2624 /SigmaFactorBS="gataaaatgtctcttcacatacagcctaaattgggtGTTGAC CTtttgataatatccgTGATATATTATTATTCGTCGctgataaacagctgacatcaac t" /listShort="S64, rrnI-16S, rrnI-23S, rrnI-5S, trnI-Asn, trnI-Thr, trnI-Gly, trnI-Arg, trnI-Pro, trnI-Ala, rrnH-16S, rrnH-23S, rrnH-5S, rrnG-16S" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 160673..160692 /Source="Nicolas_upshift_promotors" /id="U110" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp=1 /psig=1 /xcortree=2624 /SigmaFactorBS="gataaaatgtctcttcacatacagcctaaattgggtGTTGAC CTtttgataatatccgTGATATATTATTATTCGTCGctgataaacagctgacatcaac t" /listShort="S64, rrnI-16S, rrnI-23S, rrnI-5S, trnI-Asn, trnI-Thr, trnI-Gly, trnI-Arg, trnI-Pro, trnI-Ala, rrnH-16S, rrnH-23S, rrnH-5S, rrnG-16S" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 160675..160892 /Source="Nicolas_S_feature" /locus_tag="new_160675_160892" /HighExp="Diami, LBGstat, UNK1, H2O2, MG 15, Oxctl, MG-0.1, BMM, T-1.10H, Paraq" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="1, 0.998" /TUlongSig="NA" /TUlongPSig="NA" /label="S64" upshifts 160675 /Source="Nicolas_upshifts" /id="U110" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp=1 /psig=1 /xcortree=2624 /SigmaFactorBS="gataaaatgtctcttcacatacagcctaaattgggtGTTGAC CTtttgataatatccgTGATATATTATTATTCGTCGctgataaacagctgacatcaac t" /listShort="S64, rrnI-16S, rrnI-23S, rrnI-5S, trnI-Asn, trnI-Thr, trnI-Gly, trnI-Arg, trnI-Pro, trnI-Ala, rrnH-16S, rrnH-23S, rrnH-5S, rrnG-16S" /GFF_Attribute="listLong" rRNA 160893..162445 /gene="rrnI-16S" /locus_tag="BSU_rRNA_23" /product="ribosomal RNA-16S" /note="Evidence 1a: Function from experimental evidences in the studied strain; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene 160893..162445 /gene="rrnI-16S" /locus_tag="BSU_rRNA_23" rRNA 162610..165535 /gene="rrnI-23S" /locus_tag="BSU_rRNA_14" /product="ribosomal RNA-23S" /note="Evidence 1a: Function from experimental evidences in the studied strain; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene 162610..165535 /gene="rrnI-23S" /locus_tag="BSU_rRNA_14" rRNA 165591..165707 /gene="rrnI-5S" /locus_tag="BSU_rRNA_15" /product="ribosomal RNA-5S" /note="Evidence 2a: Function from experimental evidences in other organisms; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene 165591..165707 /gene="rrnI-5S" /locus_tag="BSU_rRNA_15" tRNA 165754..165825 /gene="trnI-Asn" /locus_tag="BSU_tRNA_23" /product="tRNA-Asn" /inference="profile:tRNAscan:1.23" /note="transfer RNA-Asn(GUU); Evidence 2a: Function from experimental evidences in other organisms; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene 165754..165825 /gene="trnI-Asn" /locus_tag="BSU_tRNA_23" tRNA 165830..165902 /gene="trnI-Thr" /locus_tag="BSU_tRNA_24" /product="tRNA-Thr" /inference="profile:tRNAscan:1.23" /note="transfer RNA-Thr(GGU); Evidence 2a: Function from experimental evidences in other organisms; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene 165830..165902 /gene="trnI-Thr" /locus_tag="BSU_tRNA_24" tRNA 165959..166033 /gene="trnI-Gly" /locus_tag="BSU_tRNA_25" /product="tRNA-Gly" /inference="profile:tRNAscan:1.23" /note="transfer RNA-Gly(GCC); Evidence 2a: Function from experimental evidences in other organisms; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene 165959..166033 /gene="trnI-Gly" /locus_tag="BSU_tRNA_25" tRNA 166064..166140 /gene="trnI-Arg" /locus_tag="BSU_tRNA_26" /product="tRNA-Arg" /inference="profile:tRNAscan:1.23" /note="transfer RNA-Arg(AGC); Evidence 2a: Function from experimental evidences in other organisms; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene 166064..166140 /gene="trnI-Arg" /locus_tag="BSU_tRNA_26" tRNA 166168..166244 /gene="trnI-Pro" /locus_tag="BSU_tRNA_27" /product="tRNA-Pro" /inference="profile:tRNAscan:1.23" /note="Evidence 2a: Function from experimental evidences in other organisms; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene 166168..166244 /gene="trnI-Pro" /locus_tag="BSU_tRNA_27" tRNA 166253..166328 /gene="trnI-Ala" /locus_tag="BSU_tRNA_28" /product="tRNA-Ala" /inference="profile:tRNAscan:1.23" /note="transfer RNA-Ala(UGC); Evidence 2a: Function from experimental evidences in other organisms; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene 166253..166328 /gene="trnI-Ala" /locus_tag="BSU_tRNA_28" rRNA 166500..168053 /gene="rrnH-16S" /locus_tag="BSU_rRNA_16" /product="ribosomal RNA-16S" /note="Evidence 1a: Function from experimental evidences in the studied strain; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene 166500..168053 /gene="rrnH-16S" /locus_tag="BSU_rRNA_16" rRNA 168218..171141 /gene="rrnH-23S" /locus_tag="BSU_rRNA_29" /product="ribosomal RNA-23S" /note="Evidence 1a: Function from experimental evidences in the studied strain; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene 168218..171141 /gene="rrnH-23S" /locus_tag="BSU_rRNA_29" rRNA 171197..171314 /gene="rrnH-5S" /locus_tag="BSU_rRNA_24" /product="ribosomal RNA-5S" /note="Evidence 1a: Function from experimental evidences in the studied strain; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene 171197..171314 /gene="rrnH-5S" /locus_tag="BSU_rRNA_24" rRNA 171498..173049 /gene="rrnG-16S" /locus_tag="BSU_rRNA_25" /product="ribosomal RNA-16S" /note="Evidence 1a: Function from experimental evidences in the studied strain; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene 171498..173049 /gene="rrnG-16S" /locus_tag="BSU_rRNA_25" rRNA 173214..176141 /gene="rrnG-23S" /locus_tag="BSU_rRNA_27" /product="ribosomal RNA-23S" /note="Evidence 1a: Function from experimental evidences in the studied strain; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene 173214..176141 /gene="rrnG-23S" /locus_tag="BSU_rRNA_27" rRNA 176197..176315 /gene="rrnG-5S" /locus_tag="BSU_rRNA_28" /product="ribosomal RNA-5S" /note="Evidence 1a: Function from experimental evidences in the studied strain; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene 176197..176315 /gene="rrnG-5S" /locus_tag="BSU_rRNA_28" S_feature 176316..176924 /Source="Nicolas_S_feature" /locus_tag="new_176316_176924" /HighExp="G180, G135, C30, Oxctl, Paraq, Cold, G150, H2O2, Heat, LBGstat" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="NA" /TUshortPSig="NA" /TUlongSig="NA" /TUlongPSig="NA" /label="S65" promotor_-35 176892..176896 /Source="Nicolas_upshift_promotors" /id="U111" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.95104895104895" /psig=1 /xcortree=2510 /SigmaFactorBS="tgagccatttttttcttcagcaatcaTCTTGcgtaattgata aaaaTTTATTATGATACTCTTTGTatgacaactccttgcctcaatacaatatactcaa c" /listShort="S66, ybaR" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 176912..176931 /Source="Nicolas_upshift_promotors" /id="U111" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.95104895104895" /psig=1 /xcortree=2510 /SigmaFactorBS="tgagccatttttttcttcagcaatcaTCTTGcgtaattgata aaaaTTTATTATGATACTCTTTGTatgacaactccttgcctcaatacaatatactcaa c" /listShort="S66, ybaR" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 176926..177082 /Source="Nicolas_S_feature" /locus_tag="new_176926_177082" /HighExp="LBGstat, G180, G135, dia15, C30, Oxctl, LPhT, G150, Heat, H2O2" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S66" upshifts 176926 /Source="Nicolas_upshifts" /id="U111" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.95104895104895" /psig=1 /xcortree=2510 /SigmaFactorBS="tgagccatttttttcttcagcaatcaTCTTGcgtaattgata aaaaTTTATTATGATACTCTTTGTatgacaactccttgcctcaatacaatatactcaa c" /listShort="S66, ybaR" /GFF_Attribute="listLong" CDS 177083..178519 /gene="ybaR" /locus_tag="BSU_01580" /old_locus_tag="BSU01580" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative permease" /protein_id="NP_388039.1" /db_xref="EnsemblGenomes-Gn:BSU01580" /db_xref="EnsemblGenomes-Tr:CAB11934" /db_xref="GOA:P55189" /db_xref="InterPro:IPR001902" /db_xref="InterPro:IPR002645" /db_xref="InterPro:IPR011547" /db_xref="InterPro:IPR018045" /db_xref="InterPro:IPR036513" /db_xref="SubtiList:BG11562" /db_xref="UniProtKB/Swiss-Prot:P55189" /translation="MNNSFTLKQQWFGNIRKDILAGILVALALIPEAIGFSIIAGVDP MVGLYASFCIAIIISIFGGRPGMISAATGSMAVVMVSLVADHGLQYLFAATILTGIIQ VILGISKIARLMKFIPRSVMIGFVNALAILIFSAQLPQFEGASWSMYAMLAGSLVIIY VLPRFTTAVPSPLVAIIVMTIIAVTFHVDVRTVGDMGNISSSLPHFLIPDVPFTFETL QIIFPYSIALAFVGLLESLLTAQIIDEMTDTDSDKNKESRGQGIANIVTGFFGGMAGC AMIGQSVINTKAGGRGRLSAFVAGAFLMFLIAVLSHVVVKIPMAALVAVMVMVSVGTF DWSSLKGLKKAPLTDSIVMVVTVVTVVVTDDLSKGVFVGVLLSAVFFVAKISKLKIVS HAEDQKLRTYQVKGQIFFASVTDLTNAFIYQEDIERVVIDLTEAHVWDDSGAAALDKI VAKFKEQGIEAELKGLNKASKSLMKQMA*" gene 177083..178519 /gene="ybaR" /locus_tag="BSU_01580" /old_locus_tag="BSU01580" downshifts 178508 /Source="Nicolas_upshifts" /id="D56" /incds=0 /nref=144 /ntot=228 /MaxReadThrough="2.81758" /MaxDrop="4.71162" /score="18.4600501" /energy="-12" /TU="NA" /idTUdmin="U111" /TUdmin="-2" /isTUend="TRUE" promotor_-35 178562..178567 /Source="Nicolas_upshift_promotors" /id="U112" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.653346653346653" /psig="0.707292707292707" /xcortree=1448 /SigmaFactorBS="aatgagatctgggcttttttatatAACATAcacttaagcagc ATTGATATAATAGAGAGAAGagaaattttaaataggggacttgcatatgatgcttcag a" /listShort="ybaS" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 178580..178599 /Source="Nicolas_upshift_promotors" /id="U112" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.653346653346653" /psig="0.707292707292707" /xcortree=1448 /SigmaFactorBS="aatgagatctgggcttttttatatAACATAcacttaagcagc ATTGATATAATAGAGAGAAGagaaattttaaataggggacttgcatatgatgcttcag a" /listShort="ybaS" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 178598 /Source="Nicolas_upshifts" /id="U112" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.653346653346653" /psig="0.707292707292707" /xcortree=1448 /SigmaFactorBS="aatgagatctgggcttttttatatAACATAcacttaagcagc ATTGATATAATAGAGAGAAGagaaattttaaataggggacttgcatatgatgcttcag a" /listShort="ybaS" /GFF_Attribute="listLong" CDS 178665..179585 /gene="ybaS" /locus_tag="BSU_01590" /old_locus_tag="BSU01590" /function="7: Transport and binding proteins" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative sodium dependent transporter" /protein_id="NP_388040.2" /db_xref="EnsemblGenomes-Gn:BSU01590" /db_xref="EnsemblGenomes-Tr:CAB11935" /db_xref="GOA:P55190" /db_xref="InterPro:IPR002657" /db_xref="InterPro:IPR004710" /db_xref="SubtiList:BG11563" /db_xref="UniProtKB/Swiss-Prot:P55190" /translation="MPLLTPTSVVLGVLLSQFLNGYEWAVPWIFAFITFAGSLSANFQ SLRHALSHPLPMILALFVLHIFMPLFAWGSGHLIFKGDPLTITGLTLAVVIPTGITSL IWAAMYKGNVGLTLSIILVDTVLSPLIVPLSLSLLAGAQVHMDVWGMMKGLIVMVVIP SFLGMLFNQMSSPERTAFVSSALSPFSKLCLMAVIAINSSAIAPYFKSIDLRFAGIAV TVFFIALTGYAAAWLIGKMMKRRQEEIVSLIFTGGMRNISAGAVLAVTFFPSQVAVPV VIGMLFQQILAALFGYMLNRFELKPMLQKA*" gene 178665..179585 /gene="ybaS" /locus_tag="BSU_01590" /old_locus_tag="BSU01590" downshifts 179566 /Source="Nicolas_upshifts" /id="D57" /incds=0 /nref=33 /ntot=224 /MaxReadThrough="1.3063" /MaxDrop="3.58628" /score="13.3102824" /energy="-10.5" /TU="NA" /idTUdmin="U112" /TUdmin=0 /isTUend="TRUE" CDS complement(179595..180347) /gene="eesA" /locus_tag="BSU_01600" /old_locus_tag="BSU01600" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:12354229, 2974033, 17725565, 22210890, 28283524" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12354229, 2974033, 17725565, 22210890, 28283524; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="iron-chelator (enterobactin family) esterase" /protein_id="NP_388041.2" /db_xref="EnsemblGenomes-Gn:BSU01600" /db_xref="EnsemblGenomes-Tr:CAB11936" /db_xref="GOA:P55192" /db_xref="InterPro:IPR000801" /db_xref="InterPro:IPR029058" /db_xref="SubtiList:BG11565" /db_xref="UniProtKB/Swiss-Prot:P55192" /translation="MKGSLSEHKAGNRRFTLYLPPSYSTDSGGFPAVYVQDGSSLFQN QIELLESAFQQQRLPELVLIGIEPENRLDEYTPWPAASLSDRFTDFGGMGYHYLSDIT NQFIPLIEENWNVTREPQSRGMIGASLGGLISMFAILKYPSMFGKIGSISGSYWYENA AETIHISSLKPGTARVFMSIGSEEGREKQSIQRHMLKKTKQVHQSLKEKGFTEDQLCL SIEKGAVHHHKYFCKQFINALEWLYGKNRSTL*" gene complement(179595..180347) /gene="eesA" /locus_tag="BSU_01600" /old_locus_tag="BSU01600" downshifts complement(179619) /Source="Nicolas_upshifts" /id="D58" /incds=0 /nref=15 /ntot=115 /MaxReadThrough="0.3819" /MaxDrop="4.57603" /score="25.9728338" /energy="-10.5" /TU="NA" /idTUdmin="U114" /TUdmin=1 /isTUend="TRUE" CDS complement(180344..181354) /gene="feuC" /locus_tag="BSU_01610" /old_locus_tag="BSU01610" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1c: Function from experimental evidences in the studied genus; PubMedId: 2651410, 15849754, 16850406, 27375568; Product type t: transporter" /codon_start=1 /transl_table=11 /product="iron-uptake protein" /protein_id="NP_388042.2" /db_xref="EnsemblGenomes-Gn:BSU01610" /db_xref="EnsemblGenomes-Tr:CAB11937" /db_xref="GOA:P40411" /db_xref="InterPro:IPR000522" /db_xref="InterPro:IPR035568" /db_xref="SubtiList:BG10837" /db_xref="UniProtKB/Swiss-Prot:P40411" /translation="MAKKYALFIALILVVSYFSLTSGSFSVRPAELLSTLFQIDPNPQ YEILLFDLRLPRVVMAAIIGLGLGIAGAVIQAITRNGLADPGILGINAGAGAGIVAFM LLFQGQKEVTSIAAAMGMPLFGLIGGLIAAILIYIFAWHRGNLDSGRIILVGIAINSG FSALSLFLSLKMDPQDYQMAMVWKNGSIWSANWTYITAVLPWMLLFIPILIGKSRLLD TIRFDEDTVRSLGISSNKEKTILLVACVAIISACVSVAGSMAFVGLIAPHISRRLAGV EHRYILPLSGLIGMLLVISADFAGKLFFQPAEVPAGIILAILGVPYFLYLLFKQKKGE NA*" gene complement(180344..181354) /gene="feuC" /locus_tag="BSU_01610" /old_locus_tag="BSU01610" CDS complement(181347..182351) /gene="feuB" /locus_tag="BSU_01620" /old_locus_tag="BSU01620" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 2651410, 15849754, 16850406, 17725565; Product type t: transporter" /codon_start=1 /transl_table=11 /product="ferri-bacillibactin permease" /protein_id="NP_388043.1" /db_xref="EnsemblGenomes-Gn:BSU01620" /db_xref="EnsemblGenomes-Tr:CAB11938" /db_xref="GOA:P40410" /db_xref="InterPro:IPR000522" /db_xref="InterPro:IPR035568" /db_xref="SubtiList:BG10836" /db_xref="UniProtKB/Swiss-Prot:P40410" /translation="MYSKQWTRIILITSPFAIALSLLLSILYGAKHLSTDIVFTSLIH FDPGNTDHQIIWHSRIPRAAGALLIGAALAVSGALMQGITRNYLASPSIMGVSDGSAF IITLCMVLLPQSSSIEMMIYSFIGSALGAVLVFGLAAMMPNGFTPVQLAIIGTVTSML LSSLSAAMSIYFQISQDLSFWYSARLHQMSPDFLKLAAPFFLIGIIMAISLSKKVTAV SLGDDISKSLGQKKKTIKIMAMLSVIILTGSAVALAGKIAFVGLVVPHITRFLVGSDY SRLIPCSCILGGIFLTLCDLASRFINYPFETPIEVVTSIIGVPFFLYLIKRKGGEQNG *" gene complement(181347..182351) /gene="feuB" /locus_tag="BSU_01620" /old_locus_tag="BSU01620" CDS complement(182370..183323) /gene="feuA" /locus_tag="BSU_01630" /old_locus_tag="BSU01630" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:8388528, 16889643, 17725565, 21802011, 22303020, 25355936" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8388528, 16889643, 17725565, 21802011, 22303020, 25355936; Product type lp : lipoprotein" /codon_start=1 /transl_table=11 /product="ferri-bacillibactin-binding lipoprotein" /protein_id="NP_388044.1" /db_xref="EnsemblGenomes-Gn:BSU01630" /db_xref="EnsemblGenomes-Tr:CAB11939" /db_xref="GOA:P40409" /db_xref="InterPro:IPR002491" /db_xref="PDB:2PHZ" /db_xref="PDB:2WHY" /db_xref="PDB:2WI8" /db_xref="PDB:2XUZ" /db_xref="PDB:2XV1" /db_xref="SubtiList:BG10835" /db_xref="UniProtKB/Swiss-Prot:P40409" /translation="MKKISLTLLILLLALTAAACGSKNESTASKASGTASEKKKIEYL DKTYEVTVPTDKIAITGSVESMEDAKLLDVHPQGAISFSGKFPDMFKDITDKAEPTGE KMEPNIEKILEMKPDVILASTKFPEKTLQKISTAGTTIPVSHISSNWKENMMLLAQLT GKEKKAKKIIADYEQDLKEIKTKINDKAKDSKALVIRIRQGNIYIYPEQVYFNSTLYG DLGLKAPNEVKAAKAQELSSLEKLSEMNPDHIFVQFSDDENADKPDALKDLEKNPIWK SLKAVKEDHVYVNSVDPLAQGGTAWSKVRFLKAAAEKLTQN*" gene complement(182370..183323) /gene="feuA" /locus_tag="BSU_01630" /old_locus_tag="BSU01630" promotor_-35 182683..182689 /Source="Nicolas_upshift_promotors" /id="U113" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=157 /SigmaFactorBS="gccttaaggcctaaatcaccgtatagtgtgGAGTTGAaatac acctgttcaGGGTAAATGTAAATGTTGCcttgtctgattctgatgacaagcgcttttg a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 182704..182722 /Source="Nicolas_upshift_promotors" /id="U113" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=157 /SigmaFactorBS="gccttaaggcctaaatcaccgtatagtgtgGAGTTGAaatac acctgttcaGGGTAAATGTAAATGTTGCcttgtctgattctgatgacaagcgcttttg a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 182713 /Source="Nicolas_upshifts" /id="U113" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=157 /SigmaFactorBS="gccttaaggcctaaatcaccgtatagtgtgGAGTTGAaatac acctgttcaGGGTAAATGTAAATGTTGCcttgtctgattctgatgacaagcgcttttg a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" misc_feature complement(183354..183373) /Source="Nicolas_upshift_promotors" /id="U114" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.52947052947053" /psig="0.984015984015984" /xcortree=2097 /SigmaFactorBS="gtccatgataaatcaggaatttgtccatggtgttatatctgt tcattcTCTATAATTCCAATTGATAAtagttatcaattgaacaggaggctctatagat g" /listShort="feuA, feuB, feuC, ybbA" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(183361) /Source="Nicolas_upshifts" /id="U114" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.52947052947053" /psig="0.984015984015984" /xcortree=2097 /SigmaFactorBS="gtccatgataaatcaggaatttgtccatggtgttatatctgt tcattcTCTATAATTCCAATTGATAAtagttatcaattgaacaggaggctctatagat g" /listShort="feuA, feuB, feuC, ybbA" /GFF_Attribute="listLong" CDS complement(183414..185003) /gene="btr" /locus_tag="BSU_01640" /old_locus_tag="BSU01640" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:16889643, 17725565, 17962296, 22210890" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16889643, 17725565, 17962296, 22210890; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional activator (AraC/XylS family) of synthesis and uptake of the siderophore bacillibactin" /protein_id="NP_388045.1" /db_xref="EnsemblGenomes-Gn:BSU01640" /db_xref="EnsemblGenomes-Tr:CAB11940" /db_xref="GOA:P40408" /db_xref="InterPro:IPR002491" /db_xref="InterPro:IPR009057" /db_xref="InterPro:IPR018060" /db_xref="InterPro:IPR018062" /db_xref="InterPro:IPR020449" /db_xref="SubtiList:BG10834" /db_xref="UniProtKB/Swiss-Prot:P40408" /translation="MQNAVIYQPVQIEYLKKTSDLFSEQQLADSFVLIFHLKGNGYIS IGTNTNPLQKKTLYVCPPNETFGFTPAADGHIDACIIRLLSYIKETGQDIFTPCTESE LAKLKLMNVSHIENLAVRLQELAALWNESSQLSQLKCVIEVQSLIYDLFTASLSDQTD THSAIEKTKHYIETHADTKITLAQLSQMAGISAKHYSESFKKWTGQSVTEFITKTRIT KAKRLMAKSNCKLKEIAHQTGYQDEFYFSRIFKKYTGCSPTSYMKKRRKKIAAYGRGT MGHLIPLHHIPFAAALHPKWTSYYYQHYSTDIPVQLSAYRFNEKWEENLYTLSQAEPD VIVSMDSISPEEQDRLNRIAEVMYLPSEESWRTHFLQTASFLKEESEAEKWLADYDQQ TTAAKKTLQHVQGLRFLFLRLHKQNFYLAHNRSVREVFFGDLGFSSATTADTPSEQAI SLENIANYQADCMMLFLFKEPETIAYYQQLQQTEAWQNLSAVRDNRVYLLSLDPWNEY SACGHERIVQQTVSLLSGDCP*" gene complement(183414..185003) /gene="btr" /locus_tag="BSU_01640" /old_locus_tag="BSU01640" promotor_-10 complement(185044..185063) /Source="Nicolas_upshift_promotors" /id="U115" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.506493506493506" /psig=1 /xcortree=2112 /SigmaFactorBS="tttttttcatgctaaaaacccacccgctttaTATAGGAAaac tttcatttattTGGTACAATTTTTATTGAAAatgattatcaattgaaagcttctgaaa a" /listShort="ybbB, feuA, feuB, feuC, ybbA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(185056) /Source="Nicolas_upshifts" /id="U115" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.506493506493506" /psig=1 /xcortree=2112 /SigmaFactorBS="tttttttcatgctaaaaacccacccgctttaTATAGGAAaac tttcatttattTGGTACAATTTTTATTGAAAatgattatcaattgaaagcttctgaaa a" /listShort="ybbB, feuA, feuB, feuC, ybbA" /GFF_Attribute="listLong" promotor_-35 complement(185078..185085) /Source="Nicolas_upshift_promotors" /id="U115" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.506493506493506" /psig=1 /xcortree=2112 /SigmaFactorBS="tttttttcatgctaaaaacccacccgctttaTATAGGAAaac tttcatttattTGGTACAATTTTTATTGAAAatgattatcaattgaaagcttctgaaa a" /listShort="ybbB, feuA, feuB, feuC, ybbA" /GFF_Attribute="listLong" /label="promotor_-35" downshifts complement(185165) /Source="Nicolas_upshifts" /id="D59" /incds=0 /nref=19 /ntot=58 /MaxReadThrough="1.28464" /MaxDrop="7.13916" /score="9.64466628" /energy="-10.1" /TU="NA" /idTUdmin="U116" /TUdmin=0 /isTUend="TRUE" CDS complement(185194..186438) /gene="ybbC" /locus_tag="BSU_01650" /old_locus_tag="BSU01650" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_388046.1" /db_xref="EnsemblGenomes-Gn:BSU01650" /db_xref="EnsemblGenomes-Tr:CAB11941" /db_xref="InterPro:IPR008302" /db_xref="SubtiList:BG10833" /db_xref="UniProtKB/Swiss-Prot:P40407" /translation="MRKTIFAFLTGLMMFGTITAASASPDSKNQTAKKPKVQTGIDTL LPDYKKQLKGKRIGLITNPAGVNTSLKSSVDILYENPDIKLTALFGPEHGVRGDAQAG DEVGSYIDEKTGVPVYSLYGKTKKPTPEMLKNVDILMFDIQDVGTRFYTYIYTMAYAM EAAKENGIPFMVLDRPNPQGGNHIEGPILEPEYASFVGLYPIPLKHGMTIGELASLFN KEFSIDADLTVVKMKHWKRKMDFDDTRLPFVLPSPNMPTVESTFVYPATGLIEGTNIS EGRGTTKPFELIGAPFIKSTELEETLNSLHLPGVTFRAASFTPTFSKHQGTLCHGVQL YVTDRDKFEAVKTGLSVIKTIHDLYPEDFEFLSTGSFDKLAGNGWIRTKIENGTSVEN IINSYEKTLQQFSKTRKKYLIY*" gene complement(185194..186438) /gene="ybbC" /locus_tag="BSU_01650" /old_locus_tag="BSU01650" downshifts complement(185215) /Source="Nicolas_upshifts" /id="D60" /incds=0 /nref=11 /ntot=122 /MaxReadThrough="7.66074" /MaxDrop="4.10379" /score="9.64466628" /energy="-10.1" /TU="U116" /idTUdmin="U116" /TUdmin="-50" /isTUend="FALSE" CDS complement(186452..188380) /gene="nagZ" /locus_tag="BSU_01660" /old_locus_tag="BSU01660" /EC_number="3.2.1.52" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:8063094, 20400549, 20826810, 23177201, 26963691" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8063094, 20400549, 20826810, 23177201, 26963691; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="N-acetylglucosaminidase lipoprotein" /protein_id="NP_388047.1" /db_xref="EnsemblGenomes-Gn:BSU01660" /db_xref="EnsemblGenomes-Tr:CAB11942" /db_xref="GOA:P40406" /db_xref="InterPro:IPR001764" /db_xref="InterPro:IPR002772" /db_xref="InterPro:IPR017853" /db_xref="InterPro:IPR019800" /db_xref="InterPro:IPR036881" /db_xref="InterPro:IPR036962" /db_xref="PDB:3BMX" /db_xref="PDB:3LK6" /db_xref="PDB:3NVD" /db_xref="PDB:4GYJ" /db_xref="PDB:4GYK" /db_xref="SubtiList:BG10832" /db_xref="UniProtKB/Swiss-Prot:P40406" /translation="MRPVFPLILSAVLFLSCFFGARQTEASASKRAIDANQIVNRMSL DEKLGQMLMPDFRNWQKEGESSPQALTKMNDEVASLVKKYQFGGIILFAENVKTTKQT VQLTDDYQKASPKIPLMLSIDQEGGIVTRLGEGTNFPGNMALGAARSRINAYQTGSII GKELSALGINTDFSPVVDINNNPDNPVIGVRSFSSNRELTSRLGLYTMKGLQRQDIAS ALKHFPGHGDTDVDSHYGLPLVSHGQERLREVELYPFQKAIDAGADMVMTAHVQFPAF DDTTYKSKLDGSDILVPATLSKKVMTGLLRQEMGFNGVIVTDALNMKAIADHFGQEEA VVMAVKAGVDIALMPASVTSLKEEQKFARVIQALKEAVKNGDIPEQQINNSVERIISL KIKRGMYPARNSDSTKEKIAKAKKIVGSKQHLKAEKKLAEKAVTVLKNEQHTLPFKPK KGSRILIVAPYEEQTASIEQTIHDLIKRKKIKPVSLSKMNFASQVFKTEHEKQVKEAD YIITGSYVVKNDPVVNDGVIDDTISDSSKWATVFPRAVMKAALQHNKPFVLMSLRNPY DAANFEEAKALIAVYGFKGYANGRYLQPNIPAGVMAIFGQAKPKGTLPVDIPSVTKPG NTLYPLGYGLNIKTGRPL*" gene complement(186452..188380) /gene="nagZ" /locus_tag="BSU_01660" /old_locus_tag="BSU01660" CDS complement(188408..189733) /gene="amiE" /locus_tag="BSU_01670" /old_locus_tag="BSU01670" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:16452451, 20400549" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16452451, 20400549; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="amidase hydrolyzing N-acetylmuramyl-L-Ala bond of MurNAc peptides" /protein_id="NP_388048.2" /db_xref="EnsemblGenomes-Gn:BSU01670" /db_xref="EnsemblGenomes-Tr:CAB11943" /db_xref="InterPro:IPR001466" /db_xref="InterPro:IPR012338" /db_xref="InterPro:IPR022849" /db_xref="SubtiList:BG11566" /db_xref="UniProtKB/Swiss-Prot:O05213" /translation="MKTKTLFIFSAILTLSIFAPNETFAQTAGNLIEPKIINAETAQF STKKLRKVDQMIERDIAAGFPGAVLVVVKDGRIIKKAAYGYSKKYEGSELLRRPAKMK TRTMFDLASNTKMYATNFALQRLVSQGKLDVYEKVSAYLPGFKDQPGDLIKGKDKIRV IDVLQHQSGLPSSFYFYTPEKAGKYYSQERDKTIEYLTKIPLDYQTGTKHVYSDIGYM LLGCIVEKLTGKPLDVYTEQELYKPLRLKHTLYNPLQKGFKPKQFAATERMGNTRDGV IQFPNIRTNTLQGEVHDEKAFYSMDGVSGHAGLFSNADDMAILLQVMLNKGSYRNISL FDQKTADLFTAPSATDPTFALGWRRNGSKSMEWMFGPHASENAYGHTGWTGTVTIIDP AYNLGIALLTNKKHTPVIDPEENPNVFEGDQFPTGSYGSVITAIYEAME*" gene complement(188408..189733) /gene="amiE" /locus_tag="BSU_01670" /old_locus_tag="BSU01670" CDS complement(189790..191157) /gene="murP" /locus_tag="BSU_01680" /old_locus_tag="BSU01680" /EC_number="2.7.1.192" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 15060041, 15849754, 16850406, 10627040, 20400549, 22960854; Product type t : transporter" /codon_start=1 /transl_table=11 /product="N-acetylmuramic acid PTS permease-MurP subunit" /protein_id="NP_388049.3" /db_xref="EnsemblGenomes-Gn:BSU01680" /db_xref="EnsemblGenomes-Tr:CAB11944" /db_xref="GOA:Q797S1" /db_xref="InterPro:IPR001996" /db_xref="InterPro:IPR003352" /db_xref="InterPro:IPR013013" /db_xref="InterPro:IPR018113" /db_xref="InterPro:IPR036878" /db_xref="SubtiList:BG11567" /db_xref="UniProtKB/Swiss-Prot:Q797S1" /translation="MSKENNYHHLAQKILELCGGKSNISSYTHCMTRLRITPYDESKA DAQALRKLDGVLGVVEAETLQIILGTGVVNHVTAAFSKLVSAEEGADVKEAAAKKKAD INRKNATPFKLFLRKIASIFIPLIPALVASGLITGITKAIIQAGWLSADSQIAIILTV IGSGLFTYLGILVGINASKEFGGTPALGALAGILIINPEIAKISLFGEELLPGRGGLI GVLFAAIFIAYTEQFIRRFIPQSLDIIVTPTVSLLITGIVTYVVFMPLGGFISDAITS GLLSILDIGGIAAGFILGATFLPLVVTGLHQGLTPVHMELINSIGNDPLLPILAMGGA GQVGAAFAVFVKTKKTTLRKAIAGGLPSGLLGIGEPLIFGVTLPLGRPFLTACLGAGI GGAFQAYFQVATIAIGVSGLPLSFLVLPSQIILYIVGLFISYAAGFLLTYAFGYKDEM ASQFD*" gene complement(189790..191157) /gene="murP" /locus_tag="BSU_01680" /old_locus_tag="BSU01680" CDS complement(191183..192034) /gene="murR" /locus_tag="BSU_01690" /old_locus_tag="BSU01690" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 20400549; Product type r : regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator MurR-N-acetylmuramic acid" /protein_id="NP_388050.1" /db_xref="EnsemblGenomes-Gn:BSU01690" /db_xref="EnsemblGenomes-Tr:CAB11945" /db_xref="GOA:Q45581" /db_xref="InterPro:IPR000281" /db_xref="InterPro:IPR001347" /db_xref="InterPro:IPR009057" /db_xref="InterPro:IPR035472" /db_xref="InterPro:IPR036388" /db_xref="PDB:2O3F" /db_xref="SubtiList:BG11569" /db_xref="UniProtKB/Swiss-Prot:Q45581" /translation="MATGGLAIIQSMKHKLPPSERKLADYILAHPHKAIESTVNEISA LANSSDAAVIRLCKSLGLKGFQDLKMRVAGDLAKPTFQGYRDIVPHEPLPSISEKTAG NAIQAIQDTSDLMDYKELERAVSLLLKAHTVHFIGLGASGIVAKDAQQKWLRIHKQAT AFTDTHLVASLIANADKDDIVFAISFSGETQEIVELFAMAKEKGITTISLTQFSQTSV SALADVPLYTAHSNEALIRSAATSSRLAQLFIIDVLFLGMAAEQYETTTGYIDKTRAA IQSMRIK*" gene complement(191183..192034) /gene="murR" /locus_tag="BSU_01690" /old_locus_tag="BSU01690" CDS complement(192051..192965) /gene="murQ" /locus_tag="BSU_01700" /old_locus_tag="BSU01700" /EC_number="4.2.1.126" /function="16.13: Shape" /function="16.11: Scavenge (Catabolism)" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 15983044, 20400549, 16452451; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="D-lactyl ether N-acetylmuramic-6-phosphate acid etherase" /protein_id="NP_388051.1" /db_xref="EnsemblGenomes-Gn:BSU01700" /db_xref="EnsemblGenomes-Tr:CAB11946" /db_xref="GOA:Q45582" /db_xref="InterPro:IPR001347" /db_xref="InterPro:IPR005486" /db_xref="InterPro:IPR005488" /db_xref="SubtiList:BG11570" /db_xref="UniProtKB/Swiss-Prot:Q45582" /translation="MSEPLNLHRLTTESRNSQTVEIHKANTLGILKMINNEDMKVAAA VQEVLPDIKTAVDCAYESFQNGGRLIYTGAGTSGRLGVMDAVECPPTYSVSPDQVIGI MAGGPEAFLQAAEGIEDSEEAGAEDLRNIQLTSNDTVIAIAASGRTPYAAGALRYARK VGAHTIALTCNENSAISKDADHSIEVVVGPEAITGSTRMKAATAHKMILNMISTAVMV KIGKVYENLMVDVNVSNKKLKERAISIIQSLTNASYDTARYTLEQADHHVKTAIVMLK TSTDQKQAQTLLDEANGFIDKAIEHYHP*" gene complement(192051..192965) /gene="murQ" /locus_tag="BSU_01700" /old_locus_tag="BSU01700" promotor_-10 complement(192996..193014) /Source="Nicolas_upshift_promotors" /id="U116" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.25974025974026" /psig="0.681318681318681" /xcortree=765 /SigmaFactorBS="agtgaaataaaatttcaaaaatttaaaaacatAGTTGAAAta tcataacagaaatGAATATACTGAATATTGAGatatatcattttaaaacagggggcat c" /listShort="murQ, ybbH, ybbF, ybbE, ybbD, ybbC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(193009) /Source="Nicolas_upshifts" /id="U116" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.25974025974026" /psig="0.681318681318681" /xcortree=765 /SigmaFactorBS="agtgaaataaaatttcaaaaatttaaaaacatAGTTGAAAta tcataacagaaatGAATATACTGAATATTGAGatatatcattttaaaacagggggcat c" /listShort="murQ, ybbH, ybbF, ybbE, ybbD, ybbC" /GFF_Attribute="listLong" promotor_-35 complement(193030..193037) /Source="Nicolas_upshift_promotors" /id="U116" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.25974025974026" /psig="0.681318681318681" /xcortree=765 /SigmaFactorBS="agtgaaataaaatttcaaaaatttaaaaacatAGTTGAAAta tcataacagaaatGAATATACTGAATATTGAGatatatcattttaaaacagggggcat c" /listShort="murQ, ybbH, ybbF, ybbE, ybbD, ybbC" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(193075..193557) /gene="ybbJ" /locus_tag="BSU_01710" /old_locus_tag="BSU01710" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative acyltransferase" /protein_id="NP_388052.2" /db_xref="EnsemblGenomes-Gn:BSU01710" /db_xref="EnsemblGenomes-Tr:CAB11947" /db_xref="GOA:Q45583" /db_xref="InterPro:IPR000182" /db_xref="InterPro:IPR016181" /db_xref="SubtiList:BG11571" /db_xref="UniProtKB/Swiss-Prot:Q45583" /translation="MTQDISLSFYKPEHLPELQSFTLTNDDKRFTSLPKEVLSQALGI QDRYPVVILKDDLPVGFFILHASKETLASYSNNPFALLLSSLSLTAVHHGKGYAKKAM LLLPAFVSGYFPWCDEIILAVNHLNIRAKHLYMKSGFLDKGRRRIGPLGEQLILHHFL *" gene complement(193075..193557) /gene="ybbJ" /locus_tag="BSU_01710" /old_locus_tag="BSU01710" CDS complement(193570..194025) /gene="ybbK" /locus_tag="BSU_01720" /old_locus_tag="BSU01720" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_388053.2" /db_xref="EnsemblGenomes-Gn:BSU01720" /db_xref="EnsemblGenomes-Tr:CAB11948" /db_xref="InterPro:IPR007553" /db_xref="SubtiList:BG11572" /db_xref="UniProtKB/Swiss-Prot:Q45584" /translation="MILVSSCLGGIECRYNGSHAASEKIRKLVDEKKAVMACPELLGG FSTPREPAEIIGGTGEDVLNGTAKIVTASGEDVTELYMEGAAKTLAYAKEINASAVIL KENSPSCGSGFIYNGTFSGKKITGSGVTAALLKQAGYRVISENELNDIL*" gene complement(193570..194025) /gene="ybbK" /locus_tag="BSU_01720" /old_locus_tag="BSU01720" promotor_-10 complement(194051..194070) /Source="Nicolas_upshift_promotors" /id="U117" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.7002997002997" /psig="0.992007992007992" /xcortree=3038 /SigmaFactorBS="ttttttattttcaaactttttaactccttttttaactgaaaa agccTCccaactaaagccatTTATTTTATGATAGAGACAAgcaaagcaagagaggaga a" /listShort="ybbK, ybbJ, murQ, ybbH, ybbF" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(194072) /Source="Nicolas_upshifts" /id="U117" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.7002997002997" /psig="0.992007992007992" /xcortree=3038 /SigmaFactorBS="ttttttattttcaaactttttaactccttttttaactgaaaa agccTCccaactaaagccatTTATTTTATGATAGAGACAAgcaaagcaagagaggaga a" /listShort="ybbK, ybbJ, murQ, ybbH, ybbF" /GFF_Attribute="listLong" promotor_-35 complement(194085..194086) /Source="Nicolas_upshift_promotors" /id="U117" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.7002997002997" /psig="0.992007992007992" /xcortree=3038 /SigmaFactorBS="ttttttattttcaaactttttaactccttttttaactgaaaa agccTCccaactaaagccatTTATTTTATGATAGAGACAAgcaaagcaagagaggaga a" /listShort="ybbK, ybbJ, murQ, ybbH, ybbF" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 194145..194152 /Source="Nicolas_upshift_promotors" /id="U118" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.853146853146853" /psig=1 /xcortree=2416 /SigmaFactorBS="tttgaaaataaaaaatttaattttcctCTTTACAAacagggg gtgacctGTATATAATAACTTTTGTCAgctcgacgagaacacaacggcccgttggtca a" /listShort="trnSL-Glu2, trnSL-Val1, trnSL-Thr1, trnSL-Tyr1, trnSL-Gln2, S67" /listLong="sigW, rsiW, S68, ybbP, ybbR, glmM, NA, S69, glmS" /label="promotor_-35" promotor_-10 194167..194186 /Source="Nicolas_upshift_promotors" /id="U118" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.853146853146853" /psig=1 /xcortree=2416 /SigmaFactorBS="tttgaaaataaaaaatttaattttcctCTTTACAAacagggg gtgacctGTATATAATAACTTTTGTCAgctcgacgagaacacaacggcccgttggtca a" /listShort="trnSL-Glu2, trnSL-Val1, trnSL-Thr1, trnSL-Tyr1, trnSL-Gln2, S67" /listLong="sigW, rsiW, S68, ybbP, ybbR, glmM, NA, S69, glmS" /label="promotor_-10" upshifts 194178 /Source="Nicolas_upshifts" /id="U118" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.853146853146853" /psig=1 /xcortree=2416 /SigmaFactorBS="tttgaaaataaaaaatttaattttcctCTTTACAAacagggg gtgacctGTATATAATAACTTTTGTCAgctcgacgagaacacaacggcccgttggtca a" /listShort="trnSL-Glu2, trnSL-Val1, trnSL-Thr1, trnSL-Tyr1, trnSL-Gln2, S67" /listLong="sigW, rsiW, S68, ybbP, ybbR, glmM, NA, S69, glmS" tRNA 194205..194279 /gene="trnSL-Glu2" /locus_tag="BSU_tRNA_75" /product="tRNA-Glu" /inference="profile:tRNAscan:1.23" /note="transfer RNA-Glu(UUC); Evidence 2a: Function from experimental evidences in other organisms; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene 194205..194279 /gene="trnSL-Glu2" /locus_tag="BSU_tRNA_75" tRNA 194283..194358 /gene="trnSL-Val1" /locus_tag="BSU_tRNA_78" /product="tRNA-Val" /inference="profile:tRNAscan:1.23" /note="transfer RNA-Val(UAC); Evidence 2a: Function from experimental evidences in other organisms; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene 194283..194358 /gene="trnSL-Val1" /locus_tag="BSU_tRNA_78" tRNA 194363..194435 /gene="trnSL-Thr1" /locus_tag="BSU_tRNA_76" /product="tRNA-Thr" /inference="profile:tRNAscan:1.23" /note="transfer RNA-Thr(UGU); Evidence 2a: Function from experimental evidences in other organisms; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene 194363..194435 /gene="trnSL-Thr1" /locus_tag="BSU_tRNA_76" tRNA 194458..194542 /gene="trnSL-Tyr1" /locus_tag="BSU_tRNA_77" /product="tRNA-Tyr" /inference="profile:tRNAscan:1.23" /note="transfer RNA-Tyr(GAU); Evidence 2a: Function from experimental evidences in other organisms; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene 194458..194542 /gene="trnSL-Tyr1" /locus_tag="BSU_tRNA_77" tRNA 194547..194621 /gene="trnSL-Gln2" /locus_tag="BSU_tRNA_74" /product="tRNA-Gln" /inference="profile:tRNAscan:1.23" /note="transfer RNA-Gln(UUG); Evidence 2a: Function from experimental evidences in other organisms; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene 194547..194621 /gene="trnSL-Gln2" /locus_tag="BSU_tRNA_74" downshifts 194624 /Source="Nicolas_upshifts" /id="D61" /incds=0 /nref=10 /ntot=91 /MaxReadThrough="4.25215" /MaxDrop="3.84626" /score="25.5087424" /energy="-11.4" /TU="U118" /idTUdmin="U118" /TUdmin="-176" /isTUend="FALSE" S_feature 194669..194786 /Source="Nicolas_S_feature" /locus_tag="new_194669_194786" /HighExp="Paraq, BMM, H2O2, Heat, G180, G135, Oxctl, G150, C30, Lbexp" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S67" promotor_-35 194787..194796 /Source="Nicolas_upshift_promotors" /id="U119" /multdbtbs="SigW" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1680 /SigmaFactorBS="ttcacgaattaccatctacaccctgccaaaaatttgataaac ttattttataaaaaaatTGAAACCTTTtgaaacgaagcTCGTATACATACAGACcggt g" /listShort="sigW, rsiW" /listLong="S68, ybbP, ybbR, glmM, NA, S69, glmS" /label="promotor_-35" upshifts 194788 /Source="Nicolas_upshifts" /id="U119" /multdbtbs="SigW" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1680 /SigmaFactorBS="ttcacgaattaccatctacaccctgccaaaaatttgataaac ttattttataaaaaaatTGAAACCTTTtgaaacgaagcTCGTATACATACAGACcggt g" /listShort="sigW, rsiW" /listLong="S68, ybbP, ybbR, glmM, NA, S69, glmS" promotor_-10 194808..194823 /Source="Nicolas_upshift_promotors" /id="U119" /multdbtbs="SigW" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1680 /SigmaFactorBS="ttcacgaattaccatctacaccctgccaaaaatttgataaac ttattttataaaaaaatTGAAACCTTTtgaaacgaagcTCGTATACATACAGACcggt g" /listShort="sigW, rsiW" /listLong="S68, ybbP, ybbR, glmM, NA, S69, glmS" /label="promotor_-10" CDS 194849..195412 /gene="sigW" /locus_tag="BSU_01730" /old_locus_tag="BSU01730" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:11866510, 15130127, 16629676, 21542858, 28319136, 22720735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11866510, 15130127, 16629676, 21542858, 28319136, 22720735; Product type r : regulator" /codon_start=1 /transl_table=11 /product="RNA polymerase ECF(extracytoplasmic function)-type sigma factor W" /protein_id="NP_388054.1" /db_xref="EnsemblGenomes-Gn:BSU01730" /db_xref="EnsemblGenomes-Tr:CAB11949" /db_xref="GOA:Q45585" /db_xref="InterPro:IPR000838" /db_xref="InterPro:IPR007627" /db_xref="InterPro:IPR013249" /db_xref="InterPro:IPR013324" /db_xref="InterPro:IPR013325" /db_xref="InterPro:IPR014284" /db_xref="InterPro:IPR014294" /db_xref="InterPro:IPR036388" /db_xref="PDB:5WUQ" /db_xref="PDB:5WUR" /db_xref="SubtiList:BG11573" /db_xref="UniProtKB/Swiss-Prot:Q45585" /translation="MEMMIKKRIKQVKKGDQDAFADIVDIYKDKIYQLCYRMLGNVHE AEDIAQEAFIRAYVNIDSFDINRKFSTWLYRIATNLTIDRIRKKKPDYYLDAEVAGTE GLTMYSQIVADGVLPEDAVVSLELSNTIQQKILKLPDKYRTVIVLKYIDELSLIEIGE ILNIPVGTVKTRIHRGREALRKQLRDL*" gene 194849..195412 /gene="sigW" /locus_tag="BSU_01730" /old_locus_tag="BSU01730" CDS 195426..196052 /gene="rsiW" /locus_tag="BSU_01740" /old_locus_tag="BSU01740" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:15130127, 28319136, 22720735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15130127, 28319136, 22720735; Product type r: regulator" /codon_start=1 /transl_table=11 /product="anti-sigma(W) factor" /protein_id="NP_388055.1" /db_xref="EnsemblGenomes-Gn:BSU01740" /db_xref="EnsemblGenomes-Tr:CAB11950" /db_xref="GOA:Q45588" /db_xref="InterPro:IPR027383" /db_xref="PDB:5WUQ" /db_xref="PDB:5WUR" /db_xref="SubtiList:BG11574" /db_xref="UniProtKB/Swiss-Prot:Q45588" /translation="MSCPEQIVQLMHMHLDGDILPKDEHVLNEHLETCEKCRKHFYEM EKSIALVRSTSHVEAPADFTANVMAKLPKEKKRASVKRWFRTHPVIAAAAVFIILMGG GFFNSWHNDHNFSVSKQPNLVVHNHTVTVPEGETVKGDVTVKNGKLIIKGKIDGDVTV VNGEKYMASAGQVTGQIEEINQLFDWTWYKMKSAGKSVLDAFNPNGEE*" gene 195426..196052 /gene="rsiW" /locus_tag="BSU_01740" /old_locus_tag="BSU01740" downshifts complement(195844) /Source="Nicolas_upshifts" /id="D62" /incds=1 /nref=2 /ntot=181 /MaxReadThrough="1.52124" /MaxDrop="3.24828" /score="0.305471631" /energy="-6.9" /TU="NA" /idTUdmin="U120" /TUdmin=0 /isTUend="TRUE" promotor_no_box complement(196002..196102) /Source="Nicolas_upshift_promotors" /id="U120" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.95904095904096" /psig="0.002997002997003" /xcortree=56 /SigmaFactorBS="tgtgccagccctctcagcccgcaaaaaaagagcaaagcggct aacgcgctttactcttctccgttcggattgaatgcatcgagtacacttttccccgcag a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_no_box" downshifts 196032 /Source="Nicolas_upshifts" /id="D63" /incds=0 /nref=251 /ntot=269 /MaxReadThrough="4.26924" /MaxDrop="8.34597" /score="7.39786279" /energy="-10.8" /TU="U119" /idTUdmin="U119" /TUdmin="-88" /isTUend="FALSE" upshifts complement(196042) /Source="Nicolas_upshifts" /id="U120" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.95904095904096" /psig="0.002997002997003" /xcortree=56 /SigmaFactorBS="tgtgccagccctctcagcccgcaaaaaaagagcaaagcggct aacgcgctttactcttctccgttcggattgaatgcatcgagtacacttttccccgcag a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 196101..196108 /Source="Nicolas_upshift_promotors" /id="U121" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.73026973026973" /psig=1 /xcortree=1886 /SigmaFactorBS="tctttttttgcgggctgagagggctggcaCATTTCACttgct aaatcgaaaTGTGGTATAATGGGCTCGCTatgtaaagtacatatgcgtaacacgtaaa a" /listShort="S68, ybbP, ybbR, glmM" /listLong="NA, S69, glmS" /label="promotor_-35" promotor_-10 196123..196142 /Source="Nicolas_upshift_promotors" /id="U121" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.73026973026973" /psig=1 /xcortree=1886 /SigmaFactorBS="tctttttttgcgggctgagagggctggcaCATTTCACttgct aaatcgaaaTGTGGTATAATGGGCTCGCTatgtaaagtacatatgcgtaacacgtaaa a" /listShort="S68, ybbP, ybbR, glmM" /listLong="NA, S69, glmS" /label="promotor_-10" S_feature 196132..196212 /Source="Nicolas_S_feature" /locus_tag="new_196132_196212" /HighExp="dia5, Diami, H2O2, dia15, G135, Cold, G180, Paraq, G150, Oxctl" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="SigWXY, SigA" /TUlongPSig="1, 1" /label="S68" upshifts 196132 /Source="Nicolas_upshifts" /id="U121" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.73026973026973" /psig=1 /xcortree=1886 /SigmaFactorBS="tctttttttgcgggctgagagggctggcaCATTTCACttgct aaatcgaaaTGTGGTATAATGGGCTCGCTatgtaaagtacatatgcgtaacacgtaaa a" /listShort="S68, ybbP, ybbR, glmM" /listLong="NA, S69, glmS" CDS 196213..197034 /gene="cdaA" /locus_tag="BSU_01750" /old_locus_tag="BSU01750" /EC_number="2.7.7.85" /function="16.13: Shape" /function="16.3: Control" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:19901023, 21566650, 23192352, 25605729, 25616256, 26240071, 28420751" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 19901023, 21566650, 23192352, 25605729, 25616256, 26240071, 28420751; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="diadenylate cyclase" /protein_id="NP_388056.2" /db_xref="EnsemblGenomes-Gn:BSU01750" /db_xref="EnsemblGenomes-Tr:CAB11951" /db_xref="GOA:Q45589" /db_xref="InterPro:IPR003390" /db_xref="InterPro:IPR014046" /db_xref="InterPro:IPR034701" /db_xref="InterPro:IPR036888" /db_xref="SubtiList:BG11577" /db_xref="UniProtKB/Swiss-Prot:Q45589" /translation="MAFEDIPFLQYLGNAVDILLVWYVIYKLIMVIRGTKAVQLLKGI VVIVLVRMASQYLGLSTLQWLMDQAITWGFLAIIIIFQPELRRALEQLGRGRFFSRSG TPVEEAQQKTIEAITKAINYMAKRRIGALLTIERDTGMGDYIETGIPLNAKVSSELLI NIFIPNTPLHDGAVIMKNNEIAAAACYLPLSESPFISKELGTRHRAAVGISEVTDSLT IIVSEETGGVSVAKNGDLHRELTEEALKEMLEAEFKKNTRDTSSNRWYWRGKKNG*" gene 196213..197034 /gene="cdaA" /locus_tag="BSU_01750" /old_locus_tag="BSU01750" CDS 197027..198478 /gene="cdaR" /locus_tag="BSU_01760" /old_locus_tag="BSU01760" /experiment="publication(s) with functional evidences, PMID:16236721, 17406245, 20094656, 21154411, 22720735, 23192352, 27074767" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16236721, 17406245, 20094656, 21154411, 22720735, 23192352, 27074767; Product type r: regulator" /codon_start=1 /transl_table=11 /product="regulator of diadenylate cyclase activity" /protein_id="NP_388057.2" /db_xref="EnsemblGenomes-Gn:BSU01760" /db_xref="EnsemblGenomes-Tr:CAB11952" /db_xref="GOA:O34659" /db_xref="InterPro:IPR012505" /db_xref="InterPro:IPR015943" /db_xref="SubtiList:BG12703" /db_xref="UniProtKB/Swiss-Prot:O34659" /translation="MDKFLNNRWAVKIIALLFALLLYVAVNSNQAPTPKKPGESFFPT STTDEATLTDIPVKAYYDDENYVVTGVPQTVNVTIKGSTSAVKKARQTKNFEIYADME HLKTGTHKVELKAKNVSDGLTISINPSVTTVTIQERTTKSFPVEVEYYNKSKMKKGYS PEQPIVSPKNVQITGSKNVIDNISLVKASVNLENADETIEKEAKVTVYDKDGNALPVD VEPSVIKITVPVTSPSKKVPFKIERTGSLPDGVSIANIESSPSEVTVYGSQDVLDSLE FIDGVSLDLSKINKDSDIEADIPLPDGVKKISPSKVTLHIEVDSEADQKFENVPIKTV GLSSSQNIEFLDPESQAIDVTAKGSPTNINKLKKSDIELYVNVSDLEDGEHSVKLEVN GPQNVTWSLGRKNAKIKLTSKKSNTSTNDNSSNTSGNQDTDKQTNDQKNNQQEDTKNT DKNNNDQNQDGNKDQNQDQDEDESTANSQSSSE*" gene 197027..198478 /gene="cdaR" /locus_tag="BSU_01760" /old_locus_tag="BSU01760" CDS 198497..199843 /gene="glmM" /locus_tag="BSU_01770" /old_locus_tag="BSU01770" /EC_number="5.4.2.10" /function="16.13: Shape" /function="16.2: Construct biomass (Anabolism)" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:10671448, 10913078, 12089032, 21154411, 26240071, 27074767" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10671448, 10913078, 12089032, 21154411, 26240071, 27074767; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="phosphoglucosamine mutase" /protein_id="NP_388058.1" /db_xref="EnsemblGenomes-Gn:BSU01770" /db_xref="EnsemblGenomes-Tr:CAB11953" /db_xref="GOA:O34824" /db_xref="InterPro:IPR005841" /db_xref="InterPro:IPR005843" /db_xref="InterPro:IPR005844" /db_xref="InterPro:IPR005845" /db_xref="InterPro:IPR005846" /db_xref="InterPro:IPR006352" /db_xref="InterPro:IPR016055" /db_xref="InterPro:IPR016066" /db_xref="InterPro:IPR036900" /db_xref="SubtiList:BG12704" /db_xref="UniProtKB/Swiss-Prot:O34824" /translation="MGKYFGTDGVRGVANSELTPELAFKVGRFGGYVLTKDKQRPKVL IGRDTRISGHMLEGALVAGLLSIGAEVMRLGVISTPGVSYLTKAMDAEAGVMISASHN PVQDNGIKFFGGDGFKLSDEQEAEIERLMDEPEDKLPRPVGADLGLVNDYFEGGQKYL QFLKQTADEDFTGIHVALDCANGATSSLATHLFADLDADVSTMGTSPNGLNINDGVGS THPEALSAFVKEKNADLGLAFDGDGDRLIAVDEKGNIVDGDQIMYICSKHLKSEGRLK DDTVVSTVMSNLGFYKALEKEGIKSVQTAVGDRYVVEAMKKDGYNVGGEQSGHLIFLD YNTTGDGLLSAIMLMNTLKATGKPLSELAAEMQKFPQLLVNVRVTDKYKVEENEKVKA VISEVEKEMNGDGRILVRPSGTEPLVRVMAEAKTKELCDEYVNRIVEVVRSEMGLE*" gene 198497..199843 /gene="glmM" /locus_tag="BSU_01770" /old_locus_tag="BSU01770" downshifts 199838 /Source="Nicolas_upshifts" /id="D64" /incds=0 /nref=126 /ntot=216 /MaxReadThrough="5.32721" /MaxDrop="5.02497" /score="13.5044076" /energy="-17.5" /TU="U121" /idTUdmin="U121" /TUdmin="-110" /isTUend="FALSE" promotor_-35 199862..199870 /Source="Nicolas_upshift_promotors" /id="U122" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.754245754245754" /psig="0.754245754245754" /xcortree=649 /SigmaFactorBS="tccggtcagaaatgggattagagtaacgaagtctattatcag agAGTGAACAAgacaagcgaggttTACATAAGATAATTGTGAGAcatacggcaaagtt g" /listShort="NA, S69, glmS" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 199878 /Source="Nicolas_upshifts" /id="U122" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.754245754245754" /psig="0.754245754245754" /xcortree=649 /SigmaFactorBS="tccggtcagaaatgggattagagtaacgaagtctattatcag agAGTGAACAAgacaagcgaggttTACATAAGATAATTGTGAGAcatacggcaaagtt g" /listShort="NA, S69, glmS" /GFF_Attribute="listLong" promotor_-10 199884..199903 /Source="Nicolas_upshift_promotors" /id="U122" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.754245754245754" /psig="0.754245754245754" /xcortree=649 /SigmaFactorBS="tccggtcagaaatgggattagagtaacgaagtctattatcag agAGTGAACAAgacaagcgaggttTACATAAGATAATTGTGAGAcatacggcaaagtt g" /listShort="NA, S69, glmS" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 199930..199935 /Source="Nicolas_upshift_promotors" /id="U123" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.623376623376623" /psig="0.999000999001" /xcortree=1722 /SigmaFactorBS="tgtgagacatacggcaaagttgcttaaaaaacaATTGACcgt ttatgccacatgTTGTAAAATCAAGCTTGTCTtgttcttattttctcaataggaaaag a" /listShort="NA, S69, glmS" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 199951..199970 /Source="Nicolas_upshift_promotors" /id="U123" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.623376623376623" /psig="0.999000999001" /xcortree=1722 /SigmaFactorBS="tgtgagacatacggcaaagttgcttaaaaaacaATTGACcgt ttatgccacatgTTGTAAAATCAAGCTTGTCTtgttcttattttctcaataggaaaag a" /listShort="NA, S69, glmS" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 199957 /Source="Nicolas_upshifts" /id="U123" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.623376623376623" /psig="0.999000999001" /xcortree=1722 /SigmaFactorBS="tgtgagacatacggcaaagttgcttaaaaaacaATTGACcgt ttatgccacatgTTGTAAAATCAAGCTTGTCTtgttcttattttctcaataggaaaag a" /listShort="NA, S69, glmS" /GFF_Attribute="listLong" misc_feature 200001..200017 /Source="Nicolas_upshift_promotors" /id="U124" /multdbtbs="-" /comp="M18" /sig="Sig-" /pcomp="0.497502497502497" /psig="0.497502497502497" /xcortree=336 /SigmaFactorBS="taaaatcaagcttgtcttgttcttattttctcaataggaaaa gaagaCGGGATTATTGCTTTACctataattatagcgcccgaactaagcgcccggaaaa a" /listShort="NA, S69, glmS" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 200014 /Source="Nicolas_upshifts" /id="U124" /multdbtbs="-" /comp="M18" /sig="Sig-" /pcomp="0.497502497502497" /psig="0.497502497502497" /xcortree=336 /SigmaFactorBS="taaaatcaagcttgtcttgttcttattttctcaataggaaaa gaagaCGGGATTATTGCTTTACctataattatagcgcccgaactaagcgcccggaaaa a" /listShort="NA, S69, glmS" /GFF_Attribute="listLong" misc_RNA 200017..200187 /gene="glmSA" /locus_tag="BSU_misc_RNA_5" /product="riboswitch and ribozyme (GlmS-glucosamine-6-P)" /experiment="publication(s) with functional evidences, PMID:16298301, 16484375, 16990543, 17114942, 17283212, 18079181, 19228039, 21317896, 21395279, 21936556, 25038539, 26240071, 28012261" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16298301, 16484375, 16990543, 17114942, 17283212, 18079181, 19228039, 21317896, 21395279, 21936556, 25038539, 26240071, 28012261; Product type n: RNA" gene 200017..200187 /gene="glmSA" /locus_tag="BSU_misc_RNA_5" S_feature 200188..200276 /Source="Nicolas_S_feature" /locus_tag="new_200188_200276" /HighExp="M40t90, M0t90, M9-stat, Lbstat, T2.30H, T2.0H, T3.0H, T1.30H, T1.0H, T3.30H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="Sig-, SigA, SigK" /TUshortPSig="0.498, 0.999, 0.754" /TUlongSig="SigA, SigWXY, SigA" /TUlongPSig="1, 1, 1" /label="S69" CDS 200277..202079 /gene="glmS" /locus_tag="BSU_01780" /old_locus_tag="BSU01780" /EC_number="2.6.1.16" /function="16.13: Shape" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 12682299, 15029187, 17114942, 17283212, 17322533, 23874669; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="L-glutamine-D-fructose-6-phosphate amidotransferase" /protein_id="NP_388059.1" /db_xref="EnsemblGenomes-Gn:BSU01780" /db_xref="EnsemblGenomes-Tr:CAB11954" /db_xref="GOA:P0CI73" /db_xref="InterPro:IPR001347" /db_xref="InterPro:IPR005855" /db_xref="InterPro:IPR017932" /db_xref="InterPro:IPR029055" /db_xref="InterPro:IPR035466" /db_xref="InterPro:IPR035490" /db_xref="SubtiList:BG10948" /db_xref="UniProtKB/Swiss-Prot:P0CI73" /translation="MCGIVGYIGQLDAKEILLKGLEKLEYRGYDSAGIAVANEQGIHV FKEKGRIADLREVVDANVEAKAGIGHTRWATHGEPSYLNAHPHQSALGRFTLVHNGVI ENYVQLKQEYLQDVELKSDTDTEVVVQVIEQFVNGGLETEEAFRKTLTLLKGSYAIAL FDNDNRETIFVAKNKSPLLVGLGDTFNVVASDAMAMLQVTNEYVELMDKEMVIVTDDQ VVIKNLDGDVITRASYIAELDASDIEKGTYPHYMLKETDEQPVVMRKIIQTYQDENGK LSVPGDIAAAVAEADRIYIIGCGTSYHAGLVGKQYIEMWANVPVEVHVASEFSYNMPL LSKKPLFIFLSQSGETADSRAVLVQVKALGHKALTITNVPGSTLSREADYTLLLHAGP EIAVASTKAYTAQIAVLAVLASVAADKNGINIGFDLVKELGIAANAMEALCDQKDEME MIAREYLTVSRNAFFIGRGLDYFVCVEGALKLKEISYIQAEGFAGGELKHGTIALIEQ GTPVFALATQEHVNLSIRGNVKEVAARGANTCIISLKGLDDADDRFVLPEVNPALAPL VSVVPLQLIAYYAALHRGCDVDKPRNLAKSVTVE*" gene 200277..202079 /gene="glmS" /locus_tag="BSU_01780" /old_locus_tag="BSU01780" S_feature complement(201802..202546) /Source="Nicolas_S_feature" /locus_tag="new_201802_202546_c" /HighExp="S8, S7, S6, S5, S4, BC, S3, Sw, C30, LoTm" /AntisenseName="glmS" /AntisenseCor="4.5056549205256403E-2" /AntisenseRegPval="-0.3" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.963" /TUlongSig="NA" /TUlongPSig="NA" /label="S70" downshifts 202065 /Source="Nicolas_upshifts" /id="D65" /incds=0 /nref=260 /ntot=277 /MaxReadThrough="3.18134" /MaxDrop="7.61794" /score="13.5044076" /energy="-17.5" /TU="NA" /idTUdmin="U122" /TUdmin=2 /isTUend="TRUE" CDS 202126..202266 /gene="ybbU" /locus_tag="BSU_01790" /old_locus_tag="BSU01790" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_009513939.1" /translation="MSKSERTSTVEKWIKEVDGTGPDYRSTMAIDLRCFLIRSVNQVK RH*" gene 202126..202266 /gene="ybbU" /locus_tag="BSU_01790" /old_locus_tag="BSU01790" CDS complement(202547..203458) /gene="alkA" /locus_tag="BSU_01800" /old_locus_tag="BSU01800" /EC_number="3.2.2.21" /function="16.8: Protect" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:7565865, 8376346, 16468998" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7565865, 8376346, 16468998; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="DNA-3-methyladenine glycosylase; prophage 1 region" /protein_id="NP_388061.1" /db_xref="EnsemblGenomes-Gn:BSU01800" /db_xref="EnsemblGenomes-Tr:CAB11956" /db_xref="GOA:P37878" /db_xref="InterPro:IPR000035" /db_xref="InterPro:IPR003265" /db_xref="InterPro:IPR011257" /db_xref="InterPro:IPR012904" /db_xref="InterPro:IPR023170" /db_xref="InterPro:IPR037046" /db_xref="SubtiList:BG10165" /db_xref="UniProtKB/Swiss-Prot:P37878" /translation="MTWHEVNDVIVITLPEIFDMNANLGYLTREKNECMYEIENNIIT KVIAIGEIRSLVQVSVINNKQMIVQFLNDSRPVEQWKREEIVKYIHEWFDLDNDLTPF YEMAKADPLLKMPARKFYGLRVIGIPDLFEALCWGVLGQQINLAFAYSLKKQFVEAFG DSIEWNGKKYWVFPPYERIARLTPTDLADIKMTVKKSEYIIGIARLMASGELSREKLM KMNFKDAEKNLIKIRGIGPWTANYVLMRCLRFPTAFPIDDVGLIHSIKILRNMNRKPT KDEILEISVPWKEWQSYATFYLWRVLY*" gene complement(202547..203458) /gene="alkA" /locus_tag="BSU_01800" /old_locus_tag="BSU01800" misc_feature complement(203505..203524) /Source="Nicolas_upshift_promotors" /id="U125" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.947052947052947" /psig="0.963036963036963" /xcortree=772 /SigmaFactorBS="aaaaaataaggtggttagaatgtaatagcaagataacaaaat gagtaaagatgattaTGTGATAAACTAATTTCAACcagcgtgagttttcttataatta t" /listShort="alkA, S70" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(203521) /Source="Nicolas_upshifts" /id="U125" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.947052947052947" /psig="0.963036963036963" /xcortree=772 /SigmaFactorBS="aaaaaataaggtggttagaatgtaatagcaagataacaaaat gagtaaagatgattaTGTGATAAACTAATTTCAACcagcgtgagttttcttataatta t" /listShort="alkA, S70" /GFF_Attribute="listLong" promotor_-35 203570..203576 /Source="Nicolas_upshift_promotors" /id="U126" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.515484515484515" /psig="0.994005994005994" /xcortree=376 /SigmaFactorBS="ttgttatcttgctattacattctaaccACCTTATttttttct atttatGAGGTTATAGTGTAGTTATCaagaatgctaaacgggagtagataaaaatggc c" /listShort="adaA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 203591..203610 /Source="Nicolas_upshift_promotors" /id="U126" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.515484515484515" /psig="0.994005994005994" /xcortree=376 /SigmaFactorBS="ttgttatcttgctattacattctaaccACCTTATttttttct atttatGAGGTTATAGTGTAGTTATCaagaatgctaaacgggagtagataaaaatggc c" /listShort="adaA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 203603 /Source="Nicolas_upshifts" /id="U126" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.515484515484515" /psig="0.994005994005994" /xcortree=376 /SigmaFactorBS="ttgttatcttgctattacattctaaccACCTTATttttttct atttatGAGGTTATAGTGTAGTTATCaagaatgctaaacgggagtagataaaaatggc c" /listShort="adaA" /GFF_Attribute="listLong" CDS 203729..204364 /gene="adaA" /locus_tag="BSU_01810" /old_locus_tag="BSU01810" /EC_number="2.1.1.63" /function="16.3: Control" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:1744039, 2120677, 7565865, 8376346" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1744039, 2120677, 7565865, 8376346; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="methylphosphotriester-DNA alkyltransferase and transcriptional regulator (AraC/XylS family)" /protein_id="NP_388062.1" /db_xref="EnsemblGenomes-Gn:BSU01810" /db_xref="EnsemblGenomes-Tr:CAB11957" /db_xref="GOA:P19219" /db_xref="InterPro:IPR004026" /db_xref="InterPro:IPR009057" /db_xref="InterPro:IPR016220" /db_xref="InterPro:IPR018060" /db_xref="InterPro:IPR018062" /db_xref="InterPro:IPR035451" /db_xref="SubtiList:BG10166" /db_xref="UniProtKB/Swiss-Prot:P19219" /translation="MPDSINNGHKESHDHRISNDAEMITDEKWQAIINNDAAYNNQFF YAVKSTGIFCKPSCKSRVPKKENVCIFPNTEQALRANFRPCKRCKPTNEKMPDSEWVD LITEYIDKNFTEKLTLESLADICHGSPYHMHRTFKKIKGITLVEYIQQVRVHAAKKYL IQTNKAIGDIAICVGIANAPYFITLFKKKTGQTPARFRQMSKMEETYNGNK*" gene 203729..204364 /gene="adaA" /locus_tag="BSU_01810" /old_locus_tag="BSU01810" CDS 204351..204890 /gene="adaB" /locus_tag="BSU_01820" /old_locus_tag="BSU01820" /EC_number="2.1.1.63" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:1744039, 2120677, 7565865, 8376346" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1744039, 2120677, 7565865, 8376346; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="O6-methylguanine-DNA methyltransferase; prophage1 region" /protein_id="NP_388063.1" /db_xref="EnsemblGenomes-Gn:BSU01820" /db_xref="EnsemblGenomes-Tr:CAB11958" /db_xref="GOA:P19220" /db_xref="InterPro:IPR001497" /db_xref="InterPro:IPR008332" /db_xref="InterPro:IPR014048" /db_xref="InterPro:IPR036217" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036631" /db_xref="SubtiList:BG10167" /db_xref="UniProtKB/Swiss-Prot:P19220" /translation="METNKPTLYWSLLMFKDWNFYIASTLKGLVFVGSQNKPIEELFE WARKRFPGSLLVEDDDKLEPYAVEITQYLEGKRKNFTVPVEYAGTQFQLAVWNALCEI PYGQTKSYSDIANDINKPAAVRAVGAAIGANPVLITVPCHRVIGKNGSLTGYRGGFEM KTLLLDLEKRASSEMDVPH*" gene 204351..204890 /gene="adaB" /locus_tag="BSU_01820" /old_locus_tag="BSU01820" S_feature 204891..204975 /Source="Nicolas_S_feature" /locus_tag="new_204891_204975" /HighExp="Sw, BC, S8, S6, S7, S3, G135, S4, G180, LPhT" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.77593299999999998" /TUshortSig="NA" /TUshortPSig="NA" /TUlongSig="NA" /TUlongPSig="NA" /label="S71" promotor_-35 204954..204961 /Source="Nicolas_upshift_promotors" /id="U127" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.886113886113886" /psig="0.976023976023976" /xcortree=2989 /SigmaFactorBS="ttcttttagaggaaagtaaagaccagtttactgataaACTTG ACAacttttaaaatttaGCATATCTTATACGTAACTTaataatcgatgcagatgttta t" /listShort="S72, S73, ndhF, ybcC, S74, ybcF, ybcH, ybcI, S75, ybzH" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 204976..204995 /Source="Nicolas_upshift_promotors" /id="U127" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.886113886113886" /psig="0.976023976023976" /xcortree=2989 /SigmaFactorBS="ttcttttagaggaaagtaaagaccagtttactgataaACTTG ACAacttttaaaatttaGCATATCTTATACGTAACTTaataatcgatgcagatgttta t" /listShort="S72, S73, ndhF, ybcC, S74, ybcF, ybcH, ybcI, S75, ybzH" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 204977..205210 /Source="Nicolas_S_feature" /locus_tag="new_204977_205210" /HighExp="HiOs, Heat, HiTm, MG 150, dia15, MG-0.2, Lbtran, GM-0.2, M9-stat, dia5" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.976" /TUlongSig="NA" /TUlongPSig="NA" /label="S72" upshifts 204977 /Source="Nicolas_upshifts" /id="U127" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.886113886113886" /psig="0.976023976023976" /xcortree=2989 /SigmaFactorBS="ttcttttagaggaaagtaaagaccagtttactgataaACTTG ACAacttttaaaatttaGCATATCTTATACGTAACTTaataatcgatgcagatgttta t" /listShort="S72, S73, ndhF, ybcC, S74, ybcF, ybcH, ybcI, S75, ybzH" /GFF_Attribute="listLong" downshifts 205167 /Source="Nicolas_upshifts" /id="D66" /incds=0 /nref=60 /ntot=223 /MaxReadThrough="6.74927" /MaxDrop="5.18296" /score="13.5044076" /energy="-17.5" /TU="U127" /idTUdmin="U126" /TUdmin=1344 /isTUend="FALSE" S_feature 205212..205408 /Source="Nicolas_S_feature" /locus_tag="new_205212_205408" /HighExp="Heat, G135, G180, UNK1, S8, C30, Gly, GM-0.2, G150, S7" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.976" /TUlongSig="NA" /TUlongPSig="NA" /label="S73" CDS 205409..206926 /gene="ndhF" /locus_tag="BSU_01830" /old_locus_tag="BSU01830" /EC_number="1.6.-.-" /function="16.10: Respire" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 10658656, 15849754, 16850406, 17015645, 6816592, 7565865; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="putative NADH dehydrogenase; prophage 1 region" /protein_id="NP_388064.1" /db_xref="EnsemblGenomes-Gn:BSU01830" /db_xref="EnsemblGenomes-Tr:CAB11959" /db_xref="GOA:P39755" /db_xref="InterPro:IPR001516" /db_xref="InterPro:IPR001750" /db_xref="SubtiList:BG10949" /db_xref="UniProtKB/Swiss-Prot:P39755" /translation="MLVSLSLSSLLTLFFIMLMASGISGLLFLHPRVPLSFVRIHIGI LALPLLVSLLILANSGVSGNVGPWHLDSLACLMTFFVLAIGFIIQRFSVRYLMGDRSY RKYFTLFTFTTGAASMTWLSGDLRLMVLFWGATLVGLTLLIRLNSAWQVASEAAKISG RLFLLSWFSLFFAMMWLFHATGQWQLSLVVTNESLAGLGEWERTGIQLLIVLAVIIPA AQWPFQRWLVESIVAPTPVSAIMHAGLVNAGGIILTRFSPLFHGGIASIILLLLASIS VLIGTGISLVQVDYKRQLVGSTIGQMGFMLIQCALGAYIAAIIHLILHGLFKATLFLQ AGSAVGRHEVSTRTNERTSYLWVMAGRILSLVIGVAFWLTAPGDGYHLISALILGWSL SVSWDQLVAFGEGRIGRIAGLTVLGGAALVYFIIHHLFYKWLHTTIFQSVQPPMSAVM IVVCLLLFGSALGTWVARHRSSVFFAVLYLWLVRLGEAKPKSVESHPDYLKQYIS*" gene 205409..206926 /gene="ndhF" /locus_tag="BSU_01830" /old_locus_tag="BSU01830" CDS 206941..209556 /gene="ybcC" /locus_tag="BSU_01845" /old_locus_tag="BSU01845" /function="18: Unknown function" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type f: factor" /codon_start=1 /transl_table=11 /product="conserved transmembrane protein coupled to NADH-ubiquinone oxidoreductase chain 5 homolog; prophage 1 region" /protein_id="NP_388065.2" /db_xref="EnsemblGenomes-Gn:BSU01845" /db_xref="EnsemblGenomes-Tr:CAB11960" /db_xref="InterPro:IPR018752" /db_xref="SubtiList:BG12706" /db_xref="UniProtKB/Swiss-Prot:O34688" /translation="MGITSVLTKDNVKKIDTDIDVQERDLNVFITSASRVIAPLWPIS TFAARNPWMGLENQPFDQVASWLKNTRDVDIYPSASMIRSAKNKGEIDEDFVEMGLQR WLDSHSYHIPRDVAERFCHAALKLDPLPSDLLSSHELEKLVSECSGLDHIENVFMQPL SSYIENQDGERLVNILDHHVIKWSKLYLDDSQAGWTMPNREEGFYRAWQHLIQYDPAL SKKQRERVKGWPKEAHLALQEALFALEIPESEIQTYLEGHLLSLPGWAGMMLWRSQQS SHEHALLTEYLAVRISMEWALIKPYLPLTNERSKKTISIAPLIAAWIHWGGLTLEEWS QMTASEQNEYLSFAYSFDEKLRKKLWLEAWEQTYTDRLSQKIISKQRETGREKSALAQ LAFCIDVRSEPFRRQLEKEGPFETIGIAGFFGVPIATCELGSKHSHASLPIIQKPQNK IKEFADEDVFKKYNQRKQAIHSLSHTFKTMKQNALSSLLLPELSGPWLTLQMAARSFV PRKAGRFIRNLREAWLRKPDTKLSLHHDATEAEIPVGFTDEEKVNYARQALKMMGLTE NIAPLVVICGHGSQSTNNPYSAALDCGACGGAAGGFNARVLAALCNLSEVREALLAEG IKIPEDTVFAAAEHNTTVDELHWLYVPELSEAAQEAFEQIEAVMPKVRHHVNAERLAQ LPNFQSKLKNPKAEANRFAEDWSEIRPEWGLARNAAFIIGKRELTQDCDLEGRAFLHN YDWKQDESGELLANIIVGPGTVAQWINLQYYASTVAPHYYGSGNKATQTVTAGLGVMQ GNASDLLAGLPWQSVMESDHEAYHSPLRLLILIQAPREYVERLLNHDSAFLQKVQNGW VRLASLDPEGCWESW*" gene 206941..209556 /gene="ybcC" /locus_tag="BSU_01845" /old_locus_tag="BSU01845" S_feature 209557..209632 /Source="Nicolas_S_feature" /locus_tag="new_209557_209632" /HighExp="Heat, G180, G135, C30, GM-0.2, UNK1, GM-0.1, BMM, G150, GM 5" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.976" /TUlongSig="NA" /TUlongPSig="NA" /label="S74" CDS 209633..210160 /gene="ybcF" /locus_tag="BSU_01860" /old_locus_tag="BSU01860" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative enzyme; prophage 1 region" /protein_id="NP_388067.1" /db_xref="EnsemblGenomes-Gn:BSU01860" /db_xref="EnsemblGenomes-Tr:CAB11962" /db_xref="GOA:O34823" /db_xref="InterPro:IPR036874" /db_xref="SubtiList:BG12708" /db_xref="UniProtKB/Swiss-Prot:O34823" /translation="MNVNQNKKVLFLTDIENGLEPILQEATNTSAENMLTIQSYGASI SHPYGEIMRSVIFAIYQEDVEEIFVVGTKDKKTSAGNGLTQLETMKDKIQTLDYLFQN CKPEFLGGTVDEWLNENSSDTIEKSVDMIRHHPLVPSYVKVRGLFVNHKGGKPSIAEV PDVKTGQAMPDHCLS*" gene 209633..210160 /gene="ybcF" /locus_tag="BSU_01860" /old_locus_tag="BSU01860" CDS 210224..210514 /gene="ybcH" /locus_tag="BSU_01870" /old_locus_tag="BSU01870" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function; prophage 1 region" /protein_id="NP_388068.1" /db_xref="EnsemblGenomes-Gn:BSU01870" /db_xref="EnsemblGenomes-Tr:CAB11963" /db_xref="SubtiList:BG12709" /db_xref="UniProtKB/Swiss-Prot:O34795" /translation="MSANLTDFVTKTIEEMNSFDRENMECIKKLIRKAIDFYHLKSYE EVEETHSGNVRFLHVHSMMEENMLSKMIVVTRNGKTDLDIEGVYEGYVVREY*" gene 210224..210514 /gene="ybcH" /locus_tag="BSU_01870" /old_locus_tag="BSU01870" CDS 210572..210946 /gene="ybcI" /locus_tag="BSU_01880" /old_locus_tag="BSU01880" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein; prophage 1 region" /protein_id="NP_388069.1" /db_xref="EnsemblGenomes-Gn:BSU01880" /db_xref="EnsemblGenomes-Tr:CAB11964" /db_xref="InterPro:IPR018745" /db_xref="SubtiList:BG12710" /db_xref="UniProtKB/Swiss-Prot:O34380" /translation="MKKSKGSIESEISKSITQWEKDYLGRGSVSVKTDILRDMIIVNL KGILTPAEYVVCGSKEGMLSIKQTRSELVESGIEGLKDIILKITGEKVKSFHTDLSSR TGERVMVFKLCNDLEKNLEKIL*" gene 210572..210946 /gene="ybcI" /locus_tag="BSU_01880" /old_locus_tag="BSU01880" S_feature 210947..211412 /Source="Nicolas_S_feature" /locus_tag="new_210947_211412" /HighExp="Heat, G135, G180, C30, S8, Etha, S7, GM-0.1, GM-0.2, BMM" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.976" /TUlongSig="NA" /TUlongPSig="NA" /label="S75" promotor_-10 complement(211327..211345) /Source="Nicolas_upshift_promotors" /id="U128" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=214 /SigmaFactorBS="aatccgttttttggatatatttaattaaaGGTTTATctctga ctaattccGTGAAATGAAACTGAAGACagcatatcaattttgttcaccgcttaaattt a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(211335) /Source="Nicolas_upshifts" /id="U128" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=214 /SigmaFactorBS="aatccgttttttggatatatttaattaaaGGTTTATctctga ctaattccGTGAAATGAAACTGAAGACagcatatcaattttgttcaccgcttaaattt a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(211360..211366) /Source="Nicolas_upshift_promotors" /id="U128" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=214 /SigmaFactorBS="aatccgttttttggatatatttaattaaaGGTTTATctctga ctaattccGTGAAATGAAACTGAAGACagcatatcaattttgttcaccgcttaaattt a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 211393..211400 /Source="Nicolas_upshift_promotors" /id="U129" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.531468531468531" /psig=1 /xcortree=2370 /SigmaFactorBS="tcagagataaacctttaattaaatatatccaaaaaacggATT GACATatcgaaatataaCGATATAATAATCGATATGGaaccaattgaagtattcaaag c" /listShort="ybzH, S76, ybcL" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 211413..211432 /Source="Nicolas_upshift_promotors" /id="U129" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.531468531468531" /psig=1 /xcortree=2370 /SigmaFactorBS="tcagagataaacctttaattaaatatatccaaaaaacggATT GACATatcgaaatataaCGATATAATAATCGATATGGaaccaattgaagtattcaaag c" /listShort="ybzH, S76, ybcL" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 211414 /Source="Nicolas_upshifts" /id="U129" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.531468531468531" /psig=1 /xcortree=2370 /SigmaFactorBS="tcagagataaacctttaattaaatatatccaaaaaacggATT GACATatcgaaatataaCGATATAATAATCGATATGGaaccaattgaagtattcaaag c" /listShort="ybzH, S76, ybcL" /GFF_Attribute="listLong" CDS 211429..211731 /gene="ybzH" /locus_tag="BSU_01889" /old_locus_tag="BSU01889" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative transcriptional regulator (ArsR family); prophage 1 region" /protein_id="YP_003097670.1" /db_xref="EnsemblGenomes-Gn:BSU01889" /db_xref="EnsemblGenomes-Tr:CAX52540" /db_xref="GOA:C0H3S9" /db_xref="InterPro:IPR001845" /db_xref="InterPro:IPR011991" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="UniProtKB/Swiss-Prot:C0H3S9" /translation="MEPIEVFKALSNESRLQILQWLKEPDRHFAPHEGIDMNTIGVCV SQITDKLKMTQSTASQYLTILLRAGLIKAERIGKYTYYKRDEEAIGKLADFLKTEI*" gene 211429..211731 /gene="ybzH" /locus_tag="BSU_01889" /old_locus_tag="BSU01889" downshifts 211724 /Source="Nicolas_upshifts" /id="D67" /incds=0 /nref=175 /ntot=256 /MaxReadThrough="5.31372" /MaxDrop="5.98354" /score="13.6598797" /energy="-10.8" /TU="U129" /idTUdmin="U127" /TUdmin=25 /isTUend="FALSE" S_feature 211769..211858 /Source="Nicolas_S_feature" /locus_tag="new_211769_211858" /HighExp="dia5, Diami, C30, Heat, dia15, T2.0H, S8, S1, Cold, S7" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S76" CDS 211859..213031 /gene="ybcL" /locus_tag="BSU_01890" /old_locus_tag="BSU01890" /function="16.1: Circulate" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15812018, 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative efflux transporter; prophage 1 region" /protein_id="NP_388070.1" /db_xref="EnsemblGenomes-Gn:BSU01890" /db_xref="EnsemblGenomes-Tr:CAB11965" /db_xref="GOA:O34663" /db_xref="InterPro:IPR011701" /db_xref="InterPro:IPR020846" /db_xref="InterPro:IPR036259" /db_xref="SubtiList:BG12711" /db_xref="UniProtKB/Swiss-Prot:O34663" /translation="MSNTWKIYILAIVSFLVGTSEYIISGILDQIAHTLGITLAAAGQ LITIFSLVYALSTPVLMALTASMDRRKLMMYALGLFVFGNVLAFVLPGYGWFIAARII MAMGAGVVVVTALTIAAKIASEGKQGSAIATVVMGFTASLIIGVPLGRMIAVALGWKS VFGAIALLGLIAMVVIFFTLPYTEGDKPVPLLQQLALFKKRKVAMGLSITFFWLGGYS VAYTYLSPYLLNISGINGKLLSGVLLIFGIASLVGSKFGGYSTDKWGVPFTLVGGMTL HIVTLILLSLVTHSYIGVLVILILWSFAAWSTGPTQQFHLATIEPEMSGVLLSMNQSM MQFAMAVGAGIGGVFVENVSLASITWVGALGVMIAIIASLLIFNSQPKQALKDINQ*" gene 211859..213031 /gene="ybcL" /locus_tag="BSU_01890" /old_locus_tag="BSU01890" promotor_-35 212376..212383 /Source="Nicolas_upshift_promotors" /id="U130" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.541458541458541" /psig="0.978021978021978" /xcortree=2180 /SigmaFactorBS="atttggagccattgctttgttgggattgatcgcaaTGGTCGT TattttctttactcTTCCGTATACTGAAGGGGATaagcctgtgcctttgcttcaacag c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 212397..212416 /Source="Nicolas_upshift_promotors" /id="U130" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.541458541458541" /psig="0.978021978021978" /xcortree=2180 /SigmaFactorBS="atttggagccattgctttgttgggattgatcgcaaTGGTCGT TattttctttactcTTCCGTATACTGAAGGGGATaagcctgtgcctttgcttcaacag c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 212401 /Source="Nicolas_upshifts" /id="U130" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.541458541458541" /psig="0.978021978021978" /xcortree=2180 /SigmaFactorBS="atttggagccattgctttgttgggattgatcgcaaTGGTCGT TattttctttactcTTCCGTATACTGAAGGGGATaagcctgtgcctttgcttcaacag c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" downshifts 213016 /Source="Nicolas_upshifts" /id="D68" /incds=0 /nref=8 /ntot=59 /MaxReadThrough="0.16425" /MaxDrop="4.4712" /score="19.9212489" /energy="-11" /TU="NA" /idTUdmin="U129" /TUdmin="-3" /isTUend="TRUE" CDS 213155..213469 /gene="ybcM" /locus_tag="BSU_01900" /old_locus_tag="BSU01900" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative enzyme" /protein_id="NP_388071.1" /db_xref="EnsemblGenomes-Gn:BSU01900" /db_xref="EnsemblGenomes-Tr:CAB11983" /db_xref="GOA:O31421" /db_xref="SubtiList:BG12712" /db_xref="UniProtKB/Swiss-Prot:O31421" /translation="MRFLKALPRRAEVQYDCLDRTLETQENVNLNIRVNVKEVATWGV NTCIISLKGLDNADDRFVLPEVNTALALFPLSIAADCLLMLPCISVVMSISSVMKSVT VE*" gene 213155..213469 /gene="ybcM" /locus_tag="BSU_01900" /old_locus_tag="BSU01900" misc_feature 213273..213274 /Source="Nicolas_upshift_promotors" /id="U131" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.908091908091908" /psig="0.014985014985015" /xcortree=18 /SigmaFactorBS="aacacaagagaacgtaaacctgaacatccgcgtaaacgtcaa ggaagttgCCacttggggagtaaacacttgcatcatctcgctgaaaggcctagacaat g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 213283 /Source="Nicolas_upshifts" /id="U131" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.908091908091908" /psig="0.014985014985015" /xcortree=18 /SigmaFactorBS="aacacaagagaacgtaaacctgaacatccgcgtaaacgtcaa ggaagttgCCacttggggagtaaacacttgcatcatctcgctgaaaggcctagacaat g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" downshifts 213349 /Source="Nicolas_upshifts" /id="D69" /incds=1 /nref=5 /ntot=15 /MaxReadThrough="0.469730000000001" /MaxDrop="5.4933" /score="-8.96893905" /energy="-9.8" /TU="NA" /idTUdmin="U131" /TUdmin=0 /isTUend="TRUE" promotor_-35 213850..213857 /Source="Nicolas_upshift_promotors" /id="U132" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.574425574425574" /psig="0.984015984015984" /xcortree=479 /SigmaFactorBS="atactaattaatgtaatttttaggataatatacaaaatccCC CTTACTtcgacaattgcaaTCTGGTATTATCGTATCGCAtgggagctatgtcaataga c" /listShort="S77, skfA, skfB, skfC, skfE, skfF, skfG, skfH, S78, S79, ybdG, ybdJ, ybdK, ybzI" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 213870 /Source="Nicolas_upshifts" /id="U132" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.574425574425574" /psig="0.984015984015984" /xcortree=479 /SigmaFactorBS="atactaattaatgtaatttttaggataatatacaaaatccCC CTTACTtcgacaattgcaaTCTGGTATTATCGTATCGCAtgggagctatgtcaataga c" /listShort="S77, skfA, skfB, skfC, skfE, skfF, skfG, skfH, S78, S79, ybdG, ybdJ, ybdK, ybzI" /GFF_Attribute="listLong" promotor_-10 213871..213890 /Source="Nicolas_upshift_promotors" /id="U132" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.574425574425574" /psig="0.984015984015984" /xcortree=479 /SigmaFactorBS="atactaattaatgtaatttttaggataatatacaaaatccCC CTTACTtcgacaattgcaaTCTGGTATTATCGTATCGCAtgggagctatgtcaataga c" /listShort="S77, skfA, skfB, skfC, skfE, skfF, skfG, skfH, S78, S79, ybdG, ybdJ, ybdK, ybzI" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 213878..213940 /Source="Nicolas_S_feature" /locus_tag="new_213878_213940" /HighExp="M9-stat, T5.0H, T3.0H, T2.30H, T4.0H, T3.30H, T1.30H, T1.0H, T0.0H, T0.30H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.984" /TUlongSig="NA" /TUlongPSig="NA" /label="S77" CDS 213941..214108 /gene="skfA" /locus_tag="BSU_01910" /old_locus_tag="BSU01910" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:15812018, 16816204, 17069462, 17184776, 26284661" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15812018, 16816204, 17069462, 17184776, 26284661; Product type f: factor" /codon_start=1 /transl_table=11 /product="sporulation killing factor A" /protein_id="NP_388072.1" /db_xref="EnsemblGenomes-Gn:BSU01910" /db_xref="EnsemblGenomes-Tr:CAB11984" /db_xref="GOA:O31422" /db_xref="InterPro:IPR030919" /db_xref="SubtiList:BG12713" /db_xref="UniProtKB/Swiss-Prot:O31422" /translation="MKRNQKEWESVSKKGLMKPGGTSIVKAAGCMGCWASKSIAMTRV CALPHPAMRAI*" gene 213941..214108 /gene="skfA" /locus_tag="BSU_01910" /old_locus_tag="BSU01910" downshifts complement(213954) /Source="Nicolas_upshifts" /id="D70" /incds=0 /nref=1 /ntot=70 /MaxReadThrough="0.99059" /MaxDrop="3.89647" /score="2.42246888" /energy="-3.5" /TU="NA" /idTUdmin="U134" /TUdmin=2289 /isTUend="FALSE" downshifts 214098 /Source="Nicolas_upshifts" /id="D71" /incds=0 /nref=24 /ntot=172 /MaxReadThrough="8.08284" /MaxDrop="7.24265" /score="-7.12226565" /energy="-13" /TU="U132" /idTUdmin="U131" /TUdmin=749 /isTUend="FALSE" CDS 214175..215407 /gene="skfB" /locus_tag="BSU_01920" /old_locus_tag="BSU01920" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:15812018, 16816204, 17069462, 17184776, 18307109, 23282011, 26284661" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15812018, 16816204, 17069462, 17184776, 18307109, 23282011, 26284661; Product type f: factor" /codon_start=1 /transl_table=11 /product="synthesis of sporulation killing factor A" /protein_id="NP_388073.2" /db_xref="EnsemblGenomes-Gn:BSU01920" /db_xref="EnsemblGenomes-Tr:CAB11985" /db_xref="GOA:O31423" /db_xref="InterPro:IPR000385" /db_xref="InterPro:IPR006638" /db_xref="InterPro:IPR007197" /db_xref="InterPro:IPR013785" /db_xref="InterPro:IPR023885" /db_xref="InterPro:IPR030915" /db_xref="InterPro:IPR034395" /db_xref="InterPro:IPR034481" /db_xref="SubtiList:BG12714" /db_xref="UniProtKB/Swiss-Prot:O31423" /translation="MSYDRVKDFDLPELAVHLQPHGAVMIDRKSMFYFRLSGRGAQLA FLLSKNKNLHKTARIWEIMKKEEMSADQLKEELSAHPFTEAWTEGLLDQPLHVSGSLD SYLPISCTLQLTNACNLSCSFCYASSGKPYPEELSSEQWILVMQKLAAHGVADITLTG GEAKLIKGFKELVVVASSLFTNVNVFSNGLNWRDEEVELLSHLGNVSVQISIDGMDNT HDQLRGRKGGFKESMNTIKKLSEANIPVIVAMTINESNADEVSDVVEQCANAGAFIFR AGKTLSVGRATEGFKALDIDFEEMVQIQLREARHKWGDRLNIIDWEHEESSFTTDFCT PGYLAWYIRADGYVTPCQLEDLPLGHILEDSMADIGSPARLLQLKCEAKNCKCIGKIE LSEPDLPFQKEVKAGIQE*" gene 214175..215407 /gene="skfB" /locus_tag="BSU_01920" /old_locus_tag="BSU01920" CDS 215404..216894 /gene="skfC" /locus_tag="BSU_01935" /old_locus_tag="BSU01935" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:15812018, 15849754, 16816204, 16850406, 17069462, 17184776, 26284661" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15812018, 15849754, 16816204, 16850406, 17069462, 17184776, 26284661; Product type t: transporter" /codon_start=1 /transl_table=11 /product="sporulation killing factor biosynthesis and export" /protein_id="YP_003097671.1" /db_xref="EnsemblGenomes-Gn:BSU01935" /db_xref="EnsemblGenomes-Tr:CAX52541" /db_xref="GOA:O31425" /db_xref="InterPro:IPR003675" /db_xref="UniProtKB/Swiss-Prot:O31425" /translation="MNSLSLVFWSILAVVGLLLFIKFKPPTIASLLLSKDEAKEISIQ FIKEFVGIDVENWDFYSVYWYDHDTVNKLHHLGILKKNRKVLYDVGLVESWRVRFVHQ NQSFVVGVNANREITFFYADVPKKTLSGKFEQVSPETLKQRLMASPDGLWSRANMTGT GKKEEDFREVSTYWYIAEAGDIRLKVTVELQGGRISYIGTEQEILTDQMSKVIRDEQV ESTFGVSGMLGSALAMILAILILVFMDVQTSIIFSLVLGLLIIICQSLTLKEDIQLTI VNAYDARMSVKTVSLLGILSTLLTGLLTGFVVFICSLAGNALAGDFGWKTFEQPIVQI FYGIGAGLISLGVTSLLFNLLEKKQYLRISPELSNRTVFLSGFTFRQGLNMSIQSSIG EEVIYRLLMIPVIWWMSGNILISIIVSSFLWAVMHQVTGYDPRWIRWLHLFIFGCFLG VLFIKFGFICVLVAHFIHNLVLVCMPLWQFKLQKHMHHDQPKHTSL*" gene 215404..216894 /gene="skfC" /locus_tag="BSU_01935" /old_locus_tag="BSU01935" promotor_-35 216301..216309 /Source="Nicolas_upshift_promotors" /id="U133" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=434 /SigmaFactorBS="caaaacggtcagtttattaggtattttgtctacacttcttAC AGGATTAttaacaggattTGTAGTATTTATATGTTCAttggcaggaaatgcgcttgct g" /listShort="skfE, skfF, skfG, skfH" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(216318..216337) /Source="Nicolas_upshift_promotors" /id="U134" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.996003996003996" /psig="0.996003996003996" /xcortree=1365 /SigmaFactorBS="gttgttcaaacgttttccatccaaaatcaccaGCAAGCGCAT ttcctgccaatgAACATATAAATACTACAAATcctgttaataatcctgtaagaagtgt a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-10 216321..216339 /Source="Nicolas_upshift_promotors" /id="U133" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=434 /SigmaFactorBS="caaaacggtcagtttattaggtattttgtctacacttcttAC AGGATTAttaacaggattTGTAGTATTTATATGTTCAttggcaggaaatgcgcttgct g" /listShort="skfE, skfF, skfG, skfH" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 216321 /Source="Nicolas_upshifts" /id="U133" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=434 /SigmaFactorBS="caaaacggtcagtttattaggtattttgtctacacttcttAC AGGATTAttaacaggattTGTAGTATTTATATGTTCAttggcaggaaatgcgcttgct g" /listShort="skfE, skfF, skfG, skfH" /GFF_Attribute="listLong" upshifts complement(216331) /Source="Nicolas_upshifts" /id="U134" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.996003996003996" /psig="0.996003996003996" /xcortree=1365 /SigmaFactorBS="gttgttcaaacgttttccatccaaaatcaccaGCAAGCGCAT ttcctgccaatgAACATATAAATACTACAAATcctgttaataatcctgtaagaagtgt a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(216350..216359) /Source="Nicolas_upshift_promotors" /id="U134" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.996003996003996" /psig="0.996003996003996" /xcortree=1365 /SigmaFactorBS="gttgttcaaacgttttccatccaaaatcaccaGCAAGCGCAT ttcctgccaatgAACATATAAATACTACAAATcctgttaataatcctgtaagaagtgt a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" CDS 216913..217632 /gene="skfE" /locus_tag="BSU_01950" /old_locus_tag="BSU01950" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:26284661" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 26284661; Product type t: transporter" /codon_start=1 /transl_table=11 /product="sporulation killing factor biosynthesis and export; ABC transporter (binding protein)" /protein_id="NP_388077.1" /db_xref="EnsemblGenomes-Gn:BSU01950" /db_xref="EnsemblGenomes-Tr:CAB11989" /db_xref="GOA:O31427" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG12718" /db_xref="UniProtKB/Swiss-Prot:O31427" /translation="MQLMQVQNLSKCYRNGDGVEHLSFSIQRGEIVALLGPNGAGKTT TIRCLTGLYKPDKGDILIEGSPPGDINVQKKVALIPDQPYLYPALTAAEHIQFRARGY HPGKKDVKERVYHALKEVHLEEKANQLCGQLSRGQKQRVVLAGAIVQDALLYILDEPT VGLDIPSKQWLSNWLKTKTDQGCSAFVSTHSLEFVIETADRVILIRDGKLMQDLYVPQ FEEQAEWRKEVIRLLGEWSDE*" gene 216913..217632 /gene="skfE" /locus_tag="BSU_01950" /old_locus_tag="BSU01950" CDS 217697..219040 /gene="skfF" /locus_tag="BSU_01960" /old_locus_tag="BSU01960" /function="16.11: Scavenge (Catabolism)" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:15812018, 15849754, 16816204, 16850406, 17069462, 17184776, 26284661" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15812018, 15849754, 16816204, 16850406, 17069462, 17184776, 26284661; Product type t: transporter" /codon_start=1 /transl_table=11 /product="sporulation killing factor biosynthesis and export; ABC transporter (permease)" /protein_id="NP_388078.2" /db_xref="EnsemblGenomes-Gn:BSU01960" /db_xref="EnsemblGenomes-Tr:CAB11990" /db_xref="GOA:O31428" /db_xref="InterPro:IPR030920" /db_xref="SubtiList:BG12719" /db_xref="UniProtKB/Swiss-Prot:O31428" /translation="MPFLIMLLFVGAIGFQVSFVSRSTTWDMSIAGWVLTGVFILYTA FGLFSNRLPSQMADIIWLYGTATSFSKVVYSVLFFSVTWKALLWIISAIFGDVLIVLL SGDHINLLGRSIIFVGLFFIAEVWLMSVSCARTVKKMKRVYVLVFLLMLGIYSICLYR FFFLQHSSGIWESIARFISGVGLVFDTLSPLYVVVFIGIITVSFMTIAFTSRQVEMKE SLVKEAEFWEEFQERQFGSGQIIQKPKTTWWGLQGLNGIWSFLWLELLLFKKYLFFHS IHTVMLSGVFYVVIFMYPEWFYLLFFLIVSAVMLSSYYSGIVRHSQSGTLHLFPGALW KKIIILELTNTVWLYILYCVSITFMAVGNLVYWYIYGLGIYIWFMTIRLFAFTHTNRN DIKLSLPQYYKSFFMALGLSGICLYVIHLLTADWYTLVVVVCIGSLSWCLFYRFR*" gene 217697..219040 /gene="skfF" /locus_tag="BSU_01960" /old_locus_tag="BSU01960" CDS 219087..219602 /gene="skfG" /locus_tag="BSU_01970" /old_locus_tag="BSU01970" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:15812018, 16816204, 17069462, 17184776, 26284661" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15812018, 16816204, 17069462, 17184776, 26284661; Product type ph : phenotype" /codon_start=1 /transl_table=11 /product="sporulation killing factor biosynthesis and export" /protein_id="NP_388079.2" /db_xref="EnsemblGenomes-Gn:BSU01970" /db_xref="EnsemblGenomes-Tr:CAB11991" /db_xref="GOA:O31429" /db_xref="InterPro:IPR016024" /db_xref="SubtiList:BG12720" /db_xref="UniProtKB/Swiss-Prot:O31429" /translation="MNSNGDKLSLSVQNLANTNEITIVQAIGELKKSGKDAIPVLVEA LKEEGSLCNIAAAVLGEFGEDASEAAEELSCLLKSHAEDTRMAAAISLMRIGKPSLPF VIKIAQESEGQSCFWASWCIAWIDPSCIEPKMYKCLKYEHEHPSGIVAPFAAEEALGK LIAFQLKDKED*" gene 219087..219602 /gene="skfG" /locus_tag="BSU_01970" /old_locus_tag="BSU01970" CDS 219607..220032 /gene="skfH" /locus_tag="BSU_01980" /old_locus_tag="BSU01980" /function="16.11: Scavenge (Catabolism)" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:15812018, 16816204, 17069462, 17184776, 26284661" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15812018, 16816204, 17069462, 17184776, 26284661; Product type ph : phenotype" /codon_start=1 /transl_table=11 /product="sibling killing effect; sporulation killing factor biosynthesis and export" /protein_id="NP_388080.2" /db_xref="EnsemblGenomes-Gn:BSU01980" /db_xref="EnsemblGenomes-Tr:CAB11992" /db_xref="GOA:O31430" /db_xref="InterPro:IPR012336" /db_xref="InterPro:IPR036249" /db_xref="SubtiList:BG12721" /db_xref="UniProtKB/Swiss-Prot:O31430" /translation="MKDEQMLTEWPSHLPWLNQSQNDFTFPSDTYLLLYFWSMSCPNC HQLTDKVLQDIKDMNVKVIGVHVPYIEEEKSMEVVLTYALDRGLAIPIVLDQNYEIVT TCHVQGIPSFCLLSQYGQIITKTMGDVGWDKMLKKIAGL*" gene 219607..220032 /gene="skfH" /locus_tag="BSU_01980" /old_locus_tag="BSU01980" S_feature 220033..220103 /Source="Nicolas_S_feature" /locus_tag="new_220033_220103" /HighExp="T4.0H, T5.0H, Pyr, T3.30H, S2, G/S, LoTm, T3.0H, M9-stat, T2.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.984" /TUlongSig="NA" /TUlongPSig="NA" /label="S78" downshifts 220060 /Source="Nicolas_upshifts" /id="D72" /incds=0 /nref=22 /ntot=127 /MaxReadThrough="4.07672" /MaxDrop="3.58139" /score="5.89945455" /energy="-8.8" /TU="U132" /idTUdmin="U133" /TUdmin=0 /isTUend="TRUE" S_feature 220105..220278 /Source="Nicolas_S_feature" /locus_tag="new_220105_220278" /HighExp="LoTm, T5.0H, T4.0H, T3.30H, Pyr, T-2.40H, T3.0H, T-5.40H, S2, LBGstat" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.984" /TUlongSig="NA" /TUlongPSig="NA" /label="S79" CDS 220279..221256 /gene="ybdG" /locus_tag="BSU_01990" /old_locus_tag="BSU01990" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative hydrolase/transferase" /protein_id="NP_388081.2" /db_xref="EnsemblGenomes-Gn:BSU01990" /db_xref="EnsemblGenomes-Tr:CAB11993" /db_xref="GOA:O31431" /db_xref="InterPro:IPR000073" /db_xref="InterPro:IPR029058" /db_xref="SubtiList:BG12722" /db_xref="UniProtKB/Swiss-Prot:O31431" /translation="MKTLWKVLKIVFVSLAALVLLVSVSVFIYHHFQLNKEAALLKGK GTVVDVDGKKMNVYQEGSGKDTFVFMSGSGIAAPAYEMKGLYSKFSKENKIAVVDRAG YGYSEVSHDDRDIDTVLEQTRKALMKSGNKPPYILMPHSISGIEAMYWAQKYPKEIKA IIAMDIGLPQQYVTYKLSGVDRLKVRGFHLLTSIGFHRFIPSAVYNPEVIRQSFLTDE EKEIYKAINFKQFFNADMEHELLQSYQNGSKSVNLPAPKETPVLILDAVSDQNRHSKY AIQNRKDYEAFAAQFNTADIKELRGTHSIYLYQPDQIYKLSMEFMRKVR*" gene 220279..221256 /gene="ybdG" /locus_tag="BSU_01990" /old_locus_tag="BSU01990" CDS 221258..221929 /gene="ybdJ" /locus_tag="BSU_02000" /old_locus_tag="BSU02000" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:11717295, 20035725" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11717295, 20035725; Product type r: regulator" /codon_start=1 /transl_table=11 /product="two-component system response regulator [YbdK]" /protein_id="NP_388082.1" /db_xref="EnsemblGenomes-Gn:BSU02000" /db_xref="EnsemblGenomes-Tr:CAB11994" /db_xref="GOA:O31432" /db_xref="InterPro:IPR001789" /db_xref="InterPro:IPR001867" /db_xref="InterPro:IPR011006" /db_xref="InterPro:IPR016032" /db_xref="InterPro:IPR036388" /db_xref="SubtiList:BG12723" /db_xref="UniProtKB/Swiss-Prot:O31432" /translation="MKGYRILIVEDDVMIGDLLQKILQREGYRVIWKTDGADVLSVIQ KVDLVIMDVMLPGEDGYQMSAKIKKLGLGIPVIFLSARNDMDSKLQGLQIGEDYMVKP FDPRELLLRMRNMLEHHYGTFTQIKHLYIDAVTKKVFNESLHDEVLFTAIERKIFFYL YENRDSILTKEHFFEYLWQLEDRNPNIVNVHIKKIRAKINDQAGEMIENIYGEGYRLN TVVKK*" gene 221258..221929 /gene="ybdJ" /locus_tag="BSU_02000" /old_locus_tag="BSU02000" promotor_-35 221823..221829 /Source="Nicolas_upshift_promotors" /id="U135" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.532467532467532" /psig="0.929070929070929" /xcortree=2962 /SigmaFactorBS="gatagaaacccgaatattgtcaATGTGCAtattaaaaaaatt AGAGCTAAAATCAATGATCAagcgggtgagatgattgaaaatatatatggagaagggt a" /listShort="ybdK, ybzI" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 221843..221862 /Source="Nicolas_upshift_promotors" /id="U135" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.532467532467532" /psig="0.929070929070929" /xcortree=2962 /SigmaFactorBS="gatagaaacccgaatattgtcaATGTGCAtattaaaaaaatt AGAGCTAAAATCAATGATCAagcgggtgagatgattgaaaatatatatggagaagggt a" /listShort="ybdK, ybzI" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 221861 /Source="Nicolas_upshifts" /id="U135" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.532467532467532" /psig="0.929070929070929" /xcortree=2962 /SigmaFactorBS="gatagaaacccgaatattgtcaATGTGCAtattaaaaaaatt AGAGCTAAAATCAATGATCAagcgggtgagatgattgaaaatatatatggagaagggt a" /listShort="ybdK, ybzI" /GFF_Attribute="listLong" CDS 221950..222912 /gene="ybdK" /locus_tag="BSU_02010" /old_locus_tag="BSU02010" /function="16.12: Sense" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:11717295, 20035725" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11717295, 20035725; Product type rc: receptor" /codon_start=1 /transl_table=11 /product="two-component system sensor histidine kinase [YbdJ]" /protein_id="NP_388083.1" /db_xref="EnsemblGenomes-Gn:BSU02010" /db_xref="EnsemblGenomes-Tr:CAB11995" /db_xref="GOA:O31433" /db_xref="InterPro:IPR003594" /db_xref="InterPro:IPR003660" /db_xref="InterPro:IPR003661" /db_xref="InterPro:IPR005467" /db_xref="InterPro:IPR036097" /db_xref="InterPro:IPR036890" /db_xref="SubtiList:BG12724" /db_xref="UniProtKB/Swiss-Prot:O31433" /translation="MLLFTAVISVPMLLLAVSVLMSVIYDSMFKPMNHGMPFHRSFAY PAMIVVFLISLLLLAFLFSKSIHSLLHKINLLNQTIRHLASDQRVPDKIEVKRADEIG ELIKSVNLLIERTTYRELELRQQEEIKKELLQKLRHDINTPLTALRLQLFYLEDQCHG QAVFESLYQQIEYISELTNEFNLYSAETLESSYIVNEEVRLNELLETAVKKWDYLYSM SGIELHYKPADQDVIWMSNTLWMERLFDNIFQNTLRHSKAKKMEVTIEHGDVFIRDDG IGFDRNESSEGLGLKIIEDTCRLLAITYELHTNDNGTGFLFSKE*" gene 221950..222912 /gene="ybdK" /locus_tag="BSU_02010" /old_locus_tag="BSU02010" promotor_-35 222924..222926 /Source="Nicolas_upshift_promotors" /id="U136" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.866133866133866" /psig="0.999000999001" /xcortree=2204 /SigmaFactorBS="aacggggttcttgttttcaaaagagtgaccccgctgatgTTT ttctttctcctataaAATTTATATAATAGGGAGAAagaaatggggtgaacatcatatg t" /listShort="ybzI" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 222942..222961 /Source="Nicolas_upshift_promotors" /id="U136" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.866133866133866" /psig="0.999000999001" /xcortree=2204 /SigmaFactorBS="aacggggttcttgttttcaaaagagtgaccccgctgatgTTT ttctttctcctataaAATTTATATAATAGGGAGAAagaaatggggtgaacatcatatg t" /listShort="ybzI" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 222945 /Source="Nicolas_upshifts" /id="U136" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.866133866133866" /psig="0.999000999001" /xcortree=2204 /SigmaFactorBS="aacggggttcttgttttcaaaagagtgaccccgctgatgTTT ttctttctcctataaAATTTATATAATAGGGAGAAagaaatggggtgaacatcatatg t" /listShort="ybzI" /GFF_Attribute="listLong" CDS 222971..223234 /gene="ybzI" /locus_tag="BSU_02019" /old_locus_tag="BSU02019" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="YP_003097672.1" /db_xref="EnsemblGenomes-Gn:BSU02019" /db_xref="EnsemblGenomes-Tr:CAX52542" /db_xref="UniProtKB/Swiss-Prot:C0H3T1" /translation="MNIICLKKSSKRLSTSQAVLVTDIADTGITAAAGADIIAATAAV RAKEDTTTVMAAVIVTNAGATAAVNPKKVLVPLLGQGFFYVTD*" gene 222971..223234 /gene="ybzI" /locus_tag="BSU_02019" /old_locus_tag="BSU02019" downshifts 223175 /Source="Nicolas_upshifts" /id="D73" /incds=0 /nref=120 /ntot=235 /MaxReadThrough="2.82444" /MaxDrop="4.652" /score="22.3698707" /energy="-12.1" /TU="U135" /idTUdmin="U136" /TUdmin="-6" /isTUend="TRUE" CDS complement(223219..223989) /gene="ybdM" /locus_tag="BSU_02030" /old_locus_tag="BSU02030" /EC_number="2.7.11.-" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 21304896; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative protein kinase" /protein_id="NP_388085.1" /db_xref="EnsemblGenomes-Gn:BSU02030" /db_xref="EnsemblGenomes-Tr:CAB11997" /db_xref="GOA:O31435" /db_xref="InterPro:IPR000719" /db_xref="InterPro:IPR011009" /db_xref="InterPro:IPR017441" /db_xref="SubtiList:BG12726" /db_xref="UniProtKB/Swiss-Prot:O31435" /translation="MALKLLKKLLFDRPLKNGVILNHQYKIEECLGMGGYGLVYLCTD ILAQTPYVLKQLRPTKAKKEKEKVRFQQEIKLLKNIHHPQIPGFIDEFIIDGQAYYVM QFIEGENIEELLFFRKQPFTELMALQLISQLLEIIEYLHDRLIFHSDIRTPNIIINDG RLCLIDFGLAKQLTPEEMEEIKVRKQDDFFDLGETLLFLLYSQYKGKKKKNGTWLEEL TLTKEVTLLLKRLLGIEEEYQHTASIREDLNRAIQSVT*" gene complement(223219..223989) /gene="ybdM" /locus_tag="BSU_02030" /old_locus_tag="BSU02030" CDS complement(224075..224932) /gene="ybdN" /locus_tag="BSU_02040" /old_locus_tag="BSU02040" /function="16.5: Explore" /function="16.13: Shape" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 16794953; Product type h: extrachromosomal origin" /codon_start=1 /transl_table=11 /product="putative phage protein; prophage region 1" /protein_id="NP_388086.1" /db_xref="EnsemblGenomes-Gn:BSU02040" /db_xref="EnsemblGenomes-Tr:CAB11998" /db_xref="SubtiList:BG12727" /db_xref="UniProtKB/Swiss-Prot:O31436" /translation="MVKKWLIQFAVMLSVLSTFTYSASAVGVTAITGNNSFDTAMPIG YWKYKNIDTTILEAGQDEAYFTFTANKGEKVYMRSTYQSAYTGMKIEIYDKNRIPVSQ GTEVINPNTFSSFIYANADAQNTTDTFYVKVSRGTYTGNMYFTLSIEDRIKSGSGTFQ FSGVAENKGNTSLSPSGSDSSVIKVDLTNQSGIPRDAIVTRVQTTATQTPSQGNTRHL IMTSENNEWSRALVNSSTSGSYDISLSDQLSVAKVWSFKYNTLATARSTMSNVKAKID YEYDVTKQF*" gene complement(224075..224932) /gene="ybdN" /locus_tag="BSU_02040" /old_locus_tag="BSU02040" downshifts complement(224097) /Source="Nicolas_upshifts" /id="D74" /incds=0 /nref=95 /ntot=184 /MaxReadThrough="1.56932" /MaxDrop="4.95806" /score="36.4950689" /energy="-11.9" /TU="NA" /idTUdmin="U137" /TUdmin="-4" /isTUend="TRUE" promotor_-10 complement(224146..224165) /Source="Nicolas_upshift_promotors" /id="U137" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.99000999000999" /psig="0.99000999000999" /xcortree=1343 /SigmaFactorBS="ttgtaaacagctcgacttcagggtcttatgatatctctttgt cggatcaactcAGTGTGGCAAaggtatggagtttTAAATATAATACATTAGCGAcagc c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 complement(224179..224188) /Source="Nicolas_upshift_promotors" /id="U137" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.99000999000999" /psig="0.99000999000999" /xcortree=1343 /SigmaFactorBS="ttgtaaacagctcgacttcagggtcttatgatatctctttgt cggatcaactcAGTGTGGCAAaggtatggagtttTAAATATAATACATTAGCGAcagc c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" upshifts complement(224181) /Source="Nicolas_upshifts" /id="U137" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.99000999000999" /psig="0.99000999000999" /xcortree=1343 /SigmaFactorBS="ttgtaaacagctcgacttcagggtcttatgatatctctttgt cggatcaactcAGTGTGGCAAaggtatggagtttTAAATATAATACATTAGCGAcagc c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 complement(224945..224964) /Source="Nicolas_upshift_promotors" /id="U138" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.754245754245754" /psig=1 /xcortree=2923 /SigmaFactorBS="ttttatcggcgaatataatgtatatattaacctcaaaaaaca ttTATTTACAcctaaatcgttattATGTATGATGGAAATAAAAGgaggttgtttgcat g" /listShort="ybdN" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(224970) /Source="Nicolas_upshifts" /id="U138" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.754245754245754" /psig=1 /xcortree=2923 /SigmaFactorBS="ttttatcggcgaatataatgtatatattaacctcaaaaaaca ttTATTTACAcctaaatcgttattATGTATGATGGAAATAAAAGgaggttgtttgcat g" /listShort="ybdN" /GFF_Attribute="listLong" promotor_-35 complement(224979..224986) /Source="Nicolas_upshift_promotors" /id="U138" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.754245754245754" /psig=1 /xcortree=2923 /SigmaFactorBS="ttttatcggcgaatataatgtatatattaacctcaaaaaaca ttTATTTACAcctaaatcgttattATGTATGATGGAAATAAAAGgaggttgtttgcat g" /listShort="ybdN" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 225000..225007 /Source="Nicolas_upshift_promotors" /id="U139" /multdbtbs="SigD" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2834 /SigmaFactorBS="ataataacgatttaggtgtaaataaatgttttttgagGTTAA TATatacattatattcGCCGATAAAAAAGAATAAGagagaatactcgggagggaattc a" /listShort="ybdO" /listLong="S80, ybxG" /label="promotor_-35" promotor_-10 225021..225039 /Source="Nicolas_upshift_promotors" /id="U139" /multdbtbs="SigD" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2834 /SigmaFactorBS="ataataacgatttaggtgtaaataaatgttttttgagGTTAA TATatacattatattcGCCGATAAAAAAGAATAAGagagaatactcgggagggaattc a" /listShort="ybdO" /listLong="S80, ybxG" /label="promotor_-10" upshifts 225023 /Source="Nicolas_upshifts" /id="U139" /multdbtbs="SigD" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2834 /SigmaFactorBS="ataataacgatttaggtgtaaataaatgttttttgagGTTAA TATatacattatattcGCCGATAAAAAAGAATAAGagagaatactcgggagggaattc a" /listShort="ybdO" /listLong="S80, ybxG" CDS 225064..226248 /gene="ybdO" /locus_tag="BSU_02050" /old_locus_tag="BSU02050" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15033535; Product type h: extrachromosomal origin" /codon_start=1 /transl_table=11 /product="putative phage protein; prophage region 1" /protein_id="NP_388087.1" /db_xref="EnsemblGenomes-Gn:BSU02050" /db_xref="EnsemblGenomes-Tr:CAB11999" /db_xref="InterPro:IPR032617" /db_xref="SubtiList:BG12728" /db_xref="UniProtKB/Swiss-Prot:O31437" /translation="MRLNRQFIRTQLIAQNILSKNAPAKRENATENPAAVLEKAYSRL KSQSSTGGINQFNYSKTSVSGNSGTFSKVYQSANDRTVTDTGEETVIQSQNPYESESD IRIKILDEKYSRMNAINKTKSDPLGYIKDKYQNSKSPYFRSDLSAAERQAAYDNETEW LFKGKAQNYNLQDAVFRNVTFHGEVEAENEKVYQRGQVNQQLQVLLNRNHIHIPEGTE LTFTITPIDYQVRVSGTDDQDLIKQIEQVLQSGDNSKELFLHIMKSQSSDSAQFSEEA YKKYQAAREMYEVTGYHLKDLEVIDGRYVTPEGRDLMDVYKEELEKDPVQKQTASYAI SYYRSELSKIAEAGYNAIPDFILSIDYSNGSLRDVGQSKSYGTGDTGWLEALKRQTGV NY*" gene 225064..226248 /gene="ybdO" /locus_tag="BSU_02050" /old_locus_tag="BSU02050" downshifts 226234 /Source="Nicolas_upshifts" /id="D75" /incds=0 /nref=107 /ntot=207 /MaxReadThrough="2.98334" /MaxDrop="4.9582" /score="-3.87053033" /energy="-8.3" /TU="U139" /idTUdmin="U139" /TUdmin="-181" /isTUend="FALSE" promotor_-35 226402..226408 /Source="Nicolas_upshift_promotors" /id="U140" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.430569430569431" /psig="0.999000999001" /xcortree=2998 /SigmaFactorBS="aacaaaggtgtttacctgaaaaaaacAATTGTAttttccaga gaaaTTTATTATGATGAAATAAGTaatttaggagattatataacaattttaagtttga a" /listShort="S80, ybxG" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 226422..226441 /Source="Nicolas_upshift_promotors" /id="U140" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.430569430569431" /psig="0.999000999001" /xcortree=2998 /SigmaFactorBS="aacaaaggtgtttacctgaaaaaaacAATTGTAttttccaga gaaaTTTATTATGATGAAATAAGTaatttaggagattatataacaattttaagtttga a" /listShort="S80, ybxG" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 226436..226565 /Source="Nicolas_S_feature" /locus_tag="new_226436_226565" /HighExp="Glu, LoTm, M9-stat, G135, GM-0.2, T-0.40H, Fru, UNK1, MG 120, GM-0.1" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.999" /TUlongSig="SigD" /TUlongPSig=1 /label="S80" upshifts 226436 /Source="Nicolas_upshifts" /id="U140" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.430569430569431" /psig="0.999000999001" /xcortree=2998 /SigmaFactorBS="aacaaaggtgtttacctgaaaaaaacAATTGTAttttccaga gaaaTTTATTATGATGAAATAAGTaatttaggagattatataacaattttaagtttga a" /listShort="S80, ybxG" /GFF_Attribute="listLong" CDS 226566..227954 /gene="ybxG" /locus_tag="BSU_02060" /old_locus_tag="BSU02060" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative amino acid permease" /protein_id="NP_388088.1" /db_xref="EnsemblGenomes-Gn:BSU02060" /db_xref="EnsemblGenomes-Tr:CAB12000" /db_xref="GOA:P54425" /db_xref="InterPro:IPR002293" /db_xref="InterPro:IPR004840" /db_xref="InterPro:IPR004841" /db_xref="SubtiList:BG11505" /db_xref="UniProtKB/Swiss-Prot:P54425" /translation="MANKELKRGLGARHIQMIALGGTIGVGLFMGSASTISWTGPSVL LAYAICGIFIFFIMRAMGEMLYVEPSTGSFATFGHQYIHPMAGYITAWSNWFQWIIVG MSEIIAVGSYTKYWFPDLPAWIPGIVAMVILGAANLISVKSFGEFEFWFAMIKIVTII LMIIAGIGIIFFGFGNGGDAIGLSNLWSHGGFFAGGFSGFFFALSLVIAAYQGVELIG ITAGEAKDPQNTLRNAIQSIIWRILIFYIGAIFVIVTVYPWDELNSLGSPFVSTFSKI GITAAAGIINFVVITAAMSGCNSGIFSAGRMLYTLGVNGQAPKFFKKISRNGVPLYGT IAVLIGLAVGVVLNYIAPPKIFVYVYSASVLPGMIPWFIILISHIGFRKAKGAALDKH PFKMPFAPFTNYLTIAFLLMVLVGMWFNDDTRISLIVGVIFLALVVISYYVFGIGKRT QANLTKSEQAAE*" gene 226566..227954 /gene="ybxG" /locus_tag="BSU_02060" /old_locus_tag="BSU02060" downshifts 227962 /Source="Nicolas_upshifts" /id="D76" /incds=0 /nref=121 /ntot=219 /MaxReadThrough="2.32902" /MaxDrop="5.72049" /score="28.6554212" /energy="-8.5" /TU="NA" /idTUdmin="U140" /TUdmin="-15" /isTUend="TRUE" promotor_-35 228000..228006 /Source="Nicolas_upshift_promotors" /id="U141" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=938 /SigmaFactorBS="aaaagagacattcacggatgtctctttttttatttttcgCGT ATGGattttccctatttTAGCAAGCTATAgggtaaagatagcagaaggaaaggtgttc a" /listShort="csgA, ybxH" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 228020..228031 /Source="Nicolas_upshift_promotors" /id="U141" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=938 /SigmaFactorBS="aaaagagacattcacggatgtctctttttttatttttcgCGT ATGGattttccctatttTAGCAAGCTATAgggtaaagatagcagaaggaaaggtgttc a" /listShort="csgA, ybxH" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 228021 /Source="Nicolas_upshifts" /id="U141" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=938 /SigmaFactorBS="aaaagagacattcacggatgtctctttttttatttttcgCGT ATGGattttccctatttTAGCAAGCTATAgggtaaagatagcagaaggaaaggtgttc a" /listShort="csgA, ybxH" /GFF_Attribute="listLong" CDS 228066..228314 /gene="csgA" /locus_tag="BSU_02070" /old_locus_tag="BSU02070" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:9016963" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9016963; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="sporulation-specific SASP protein" /protein_id="NP_388089.1" /db_xref="EnsemblGenomes-Gn:BSU02070" /db_xref="EnsemblGenomes-Tr:CAB12001" /db_xref="GOA:P54379" /db_xref="InterPro:IPR020255" /db_xref="SubtiList:BG11504" /db_xref="UniProtKB/Swiss-Prot:P54379" /translation="MDVTLGYLRESLSNHLENEVCQRICKKMLAKRYANEEEFVKDLD DNEMSFLNHVLEKEIKYAQNEQDQKRAKELNEVYELLL*" gene 228066..228314 /gene="csgA" /locus_tag="BSU_02070" /old_locus_tag="BSU02070" CDS 228331..228522 /gene="ybxH" /locus_tag="BSU_02080" /old_locus_tag="BSU02080" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_388090.1" /db_xref="EnsemblGenomes-Gn:BSU02080" /db_xref="EnsemblGenomes-Tr:CAB12002" /db_xref="InterPro:IPR035314" /db_xref="SubtiList:BG11506" /db_xref="UniProtKB/Swiss-Prot:P54426" /translation="MGAIERSGYTFQPEFSVVRQNGAIHVYHQGEFVEEIEFEFNGEY PDHDLIEELVNHYCFEHEI*" gene 228331..228522 /gene="ybxH" /locus_tag="BSU_02080" /old_locus_tag="BSU02080" downshifts 228504 /Source="Nicolas_upshifts" /id="D77" /incds=0 /nref=17 /ntot=40 /MaxReadThrough="0.194030000000001" /MaxDrop="4.779" /score="29.4617878" /energy="-15.6" /TU="NA" /idTUdmin="U141" /TUdmin="-1" /isTUend="TRUE" CDS complement(228549..229352) /gene="ybxI" /locus_tag="BSU_02090" /old_locus_tag="BSU02090" /EC_number="3.5.2.6" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:14742199" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 14742199; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="exported beta-lactamase" /protein_id="NP_388091.1" /db_xref="EnsemblGenomes-Gn:BSU02090" /db_xref="EnsemblGenomes-Tr:CAB12003" /db_xref="GOA:P54427" /db_xref="InterPro:IPR001460" /db_xref="InterPro:IPR002137" /db_xref="InterPro:IPR012338" /db_xref="PDB:5E2F" /db_xref="SubtiList:BG11507" /db_xref="UniProtKB/Swiss-Prot:P54427" /translation="MKKWIYVVLVLSIAGIGGFSVHAASSAHEKHLNVSKMNVDDEFK DTDGTFILHDLQKDQTFVYNRKRANQRQTPQSTFKVVNALIGLQVKAVRDEYDVKRWD GVKREFESWNRDHTLGSAMRESAIWYYQALARDIGEERMKTWLHTLSYGNEDISGGID QFWLQSSLTISPLEQETFLEKLAKEELPFDKPVMKIVKRMMIQEEGDHYTLYGKTGTR LTDMGLGWFVGFIKTEHGSYVFVTNVDDSGTKAKNITVDILKKYGLITS*" gene complement(228549..229352) /gene="ybxI" /locus_tag="BSU_02090" /old_locus_tag="BSU02090" promotor_-10 complement(229374..229392) /Source="Nicolas_upshift_promotors" /id="U142" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp=1 /psig=1 /xcortree=3196 /SigmaFactorBS="accaaatttaagcgctttttgattattttttAAAGGAAGAac aaacgaaaGAGAGAAAAGGTAGTTAATcaaaacgaaggggagaacaaaatgaaaaaat g" /listShort="ybxI" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(229382) /Source="Nicolas_upshifts" /id="U142" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp=1 /psig=1 /xcortree=3196 /SigmaFactorBS="accaaatttaagcgctttttgattattttttAAAGGAAGAac aaacgaaaGAGAGAAAAGGTAGTTAATcaaaacgaaggggagaacaaaatgaaaaaat g" /listShort="ybxI" /GFF_Attribute="listLong" promotor_-35 complement(229403..229411) /Source="Nicolas_upshift_promotors" /id="U142" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp=1 /psig=1 /xcortree=3196 /SigmaFactorBS="accaaatttaagcgctttttgattattttttAAAGGAAGAac aaacgaaaGAGAGAAAAGGTAGTTAATcaaaacgaaggggagaacaaaatgaaaaaat g" /listShort="ybxI" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 229466..229472 /Source="Nicolas_upshift_promotors" /id="U143" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=163 /SigmaFactorBS="taaatttggttttgcaaacaaatactgttactgGGTTTATag tcggaagataacGTGAAAATAGAGGGTAAAAaggaaggcagggtaagcggatgaatga g" /listShort="cypC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 229487..229505 /Source="Nicolas_upshift_promotors" /id="U143" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=163 /SigmaFactorBS="taaatttggttttgcaaacaaatactgttactgGGTTTATag tcggaagataacGTGAAAATAGAGGGTAAAAaggaaggcagggtaagcggatgaatga g" /listShort="cypC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 229493 /Source="Nicolas_upshifts" /id="U143" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=163 /SigmaFactorBS="taaatttggttttgcaaacaaatactgttactgGGTTTATag tcggaagataacGTGAAAATAGAGGGTAAAAaggaaggcagggtaagcggatgaatga g" /listShort="cypC" /GFF_Attribute="listLong" CDS 229525..230778 /gene="cypC" /locus_tag="BSU_02100" /old_locus_tag="BSU02100" /EC_number="1.11.2.4" /function="16.6: Maintain" /function="16.11: Scavenge (Catabolism)" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:10529095, 12519760, 21673922" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10529095, 12519760, 21673922; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="fatty acid beta-hydroxylating cytochrome P450" /protein_id="NP_388092.1" /db_xref="EnsemblGenomes-Gn:BSU02100" /db_xref="EnsemblGenomes-Tr:CAB12004" /db_xref="GOA:O31440" /db_xref="InterPro:IPR001128" /db_xref="InterPro:IPR002401" /db_xref="InterPro:IPR036396" /db_xref="PDB:1IZO" /db_xref="PDB:2ZQJ" /db_xref="PDB:2ZQX" /db_xref="SubtiList:BG12729" /db_xref="UniProtKB/Swiss-Prot:O31440" /translation="MNEQIPHDKSLDNSLTLLKEGYLFIKNRTERYNSDLFQARLLGK NFICMTGAEAAKVFYDTDRFQRQNALPKRVQKSLFGVNAIQGMDGSAHIHRKMLFLSL MTPPHQKRLAELMTEEWKAAVTRWEKADEVVLFEEAKEILCRVACYWAGVPLKETEVK ERADDFIDMVDAFGAVGPRHWKGRRARPRAEEWIEVMIEDARAGLLKTTSGTALHEMA FHTQEDGSQLDSRMAAIELINVLRPIVAISYFLVFSALALHEHPKYKEWLRSGNSRER EMFVQEVRRYYPFGPFLGALVKKDFVWNNCEFKKGTSVLLDLYGTNHDPRLWDHPDEF RPERFAEREENLFDMIPQGGGHAEKGHRCPGEGITIEVMKASLDFLVHQIEYDVPEQS LHYSLARMPSLPESGFVMSGIRRKS*" gene 229525..230778 /gene="cypC" /locus_tag="BSU_02100" /old_locus_tag="BSU02100" misc_feature 229837..229844 /Source="Nicolas_upshift_promotors" /id="U144" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.454545454545455" /psig="0.013986013986014" /xcortree=116 /SigmaFactorBS="atggcagcgcgcatatccatcggaagatgctttttctgtcat tgatgacaCCGCCGCAtcaaaaacgtttggctgagttgatgacagaggagtggaaagc a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 229847 /Source="Nicolas_upshifts" /id="U144" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.454545454545455" /psig="0.013986013986014" /xcortree=116 /SigmaFactorBS="atggcagcgcgcatatccatcggaagatgctttttctgtcat tgatgacaCCGCCGCAtcaaaaacgtttggctgagttgatgacagaggagtggaaagc a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" downshifts 230771 /Source="Nicolas_upshifts" /id="D78" /incds=0 /nref=5 /ntot=36 /MaxReadThrough="2.65245" /MaxDrop="6.12325" /score="-7.42298703" /energy="-14.7" /TU="NA" /idTUdmin="U143" /TUdmin=0 /isTUend="TRUE" CDS complement(230819..231079) /gene="ybyB" /locus_tag="BSU_02110" /old_locus_tag="BSU02110" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_388093.1" /db_xref="EnsemblGenomes-Gn:BSU02110" /db_xref="EnsemblGenomes-Tr:CAB12005" /db_xref="SubtiList:BG12754" /db_xref="UniProtKB/Swiss-Prot:O31441" /translation="MKQKLLLSGLAVSTVGITSYLLKDPSNRQKAREFIHSMKMKITK QPDMETFPVDKAGHPDPQDIEDNKMVSEGSMYPVQYYDEKKK*" gene complement(230819..231079) /gene="ybyB" /locus_tag="BSU_02110" /old_locus_tag="BSU02110" downshifts complement(230838) /Source="Nicolas_upshifts" /id="D79" /incds=0 /nref=155 /ntot=247 /MaxReadThrough="3.63752" /MaxDrop="7.83539" /score="8.86703843" /energy="-12.4" /TU="U145" /idTUdmin="U145" /TUdmin="-387" /isTUend="FALSE" promotor_-10 complement(231109..231127) /Source="Nicolas_upshift_promotors" /id="U145" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=227 /SigmaFactorBS="tactgttaattccaatgataaaaacacaacaGGTTTAGcaat ttccaaaacGGGAATGATACAGGAAACActattcttaaaatagaaaggagtatcacca t" /listShort="ybyB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(231118) /Source="Nicolas_upshifts" /id="U145" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=227 /SigmaFactorBS="tactgttaattccaatgataaaaacacaacaGGTTTAGcaat ttccaaaacGGGAATGATACAGGAAACActattcttaaaatagaaaggagtatcacca t" /listShort="ybyB" /GFF_Attribute="listLong" promotor_-35 complement(231141..231147) /Source="Nicolas_upshift_promotors" /id="U145" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=227 /SigmaFactorBS="tactgttaattccaatgataaaaacacaacaGGTTTAGcaat ttccaaaacGGGAATGATACAGGAAACActattcttaaaatagaaaggagtatcacca t" /listShort="ybyB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 231271..231278 /Source="Nicolas_upshift_promotors" /id="U146" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=2207 /SigmaFactorBS="atatacattgacttattatagatttcagtcaaaattcgataa aTATTGACAaagtaaagtaatcagAATAATAATATAATTAGCAAgagaatgtcatcat a" /listShort="ybeC" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 231288 /Source="Nicolas_upshifts" /id="U146" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=2207 /SigmaFactorBS="atatacattgacttattatagatttcagtcaaaattcgataa aTATTGACAaagtaaagtaatcagAATAATAATATAATTAGCAAgagaatgtcatcat a" /listShort="ybeC" /GFF_Attribute="listLong" promotor_-10 231294..231313 /Source="Nicolas_upshift_promotors" /id="U146" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=2207 /SigmaFactorBS="atatacattgacttattatagatttcagtcaaaattcgataa aTATTGACAaagtaaagtaatcagAATAATAATATAATTAGCAAgagaatgtcatcat a" /listShort="ybeC" /GFF_Attribute="listLong" /label="promotor_-10" CDS 231348..232967 /gene="ybeC" /locus_tag="BSU_02120" /old_locus_tag="BSU02120" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative H+/amino acid transporter" /protein_id="NP_388094.2" /db_xref="EnsemblGenomes-Gn:BSU02120" /db_xref="EnsemblGenomes-Tr:CAB12006" /db_xref="GOA:Q45577" /db_xref="InterPro:IPR002293" /db_xref="SubtiList:BG12730" /db_xref="UniProtKB/Swiss-Prot:Q45577" /translation="MNQLHRRMGTFSLMMVGLGSMIGSGWLFGAWRAAQIAGPAAIIS WVIGMVVILFIALSYSELGSMFPEAGGMVKYTQYSHGSFIGFIAGWANWIAIVSVIPV EAVASVQYMSSWPWEWAKWTSGLVKNGTLTGEGLAFASVLLLIYFLLNYWTVNLFSKA NSLITIFKIIIPGLTIGALLFVGFHGENFTGGQSIAPNGWASVLTAVATSGIVFAFNG FQSPINMAGEAKNPGKSIPIAVVGSLFVATVIYVLLQIAFIGAVNPSDIAHGWSHLNF NSPFADLAIALNINWLVIVLYADAFVSPSGTGITYTATTSRMIYGMEKNKYMPSIFGK LHPIYGVPRQAMFFNLIVSFIFLFLFRGWGVLAEIISVATLISYITGPITVMTLRRTG KDLYRPLRLKGLNVIAPLGFIFASLVLYWARWPLTGQVLFIILIGLPIYFYYQAKAKW KGFGRNFKAGVWMVFYLLAMMVISYLGSDKFGGLNVIHYGWDMVLIAMVSLVFYVWAL KSGYQTEYLKDAKEINSQLLNGQSEAAAGKE*" gene 231348..232967 /gene="ybeC" /locus_tag="BSU_02120" /old_locus_tag="BSU02120" downshifts 232950 /Source="Nicolas_upshifts" /id="D80" /incds=0 /nref=183 /ntot=273 /MaxReadThrough="0.8051" /MaxDrop="6.79949" /score="24.7668372" /energy="-12.2" /TU="NA" /idTUdmin="U146" /TUdmin="-21" /isTUend="TRUE" CDS complement(233014..233895) /gene="glpQA" /locus_tag="BSU_02130" /old_locus_tag="BSU02130" /EC_number="3.1.4.46" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:10913081, 21966272" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10913081, 21966272; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="secreted glycerophosphoryl diester phosphodiesterase" /protein_id="NP_388095.1" /db_xref="EnsemblGenomes-Gn:BSU02130" /db_xref="EnsemblGenomes-Tr:CAB12007" /db_xref="GOA:P37965" /db_xref="InterPro:IPR004129" /db_xref="InterPro:IPR017946" /db_xref="InterPro:IPR030395" /db_xref="PDB:5T91" /db_xref="PDB:5T9B" /db_xref="PDB:5T9C" /db_xref="SubtiList:BG10646" /db_xref="UniProtKB/Swiss-Prot:P37965" /translation="MRKNRILALFVLSLGLLSFMVTPVSAASKGNLLSPDRILTVAHR GASGYVPEHTILSYETAQKMKADFIELDLQMTKDGKLIVMHDEKLDRTTNGMGWVKDH TLADIKKLDAGSWFNEAYPEKAKPQYVGLKVPTLEEVLDRFGKHANYYIETKSPDTYP GMEEKLIASLQKHKLLGKHSKPGQVIIQSFSKESLVKVHQLQPNLPTVQLLEAKQMAS MTDAALEEIKTYAVGAGPDYKALNQENVRMIRSHGLLLHPYTVNNEADMHRLLDWGVT GVFTNYPDLFHKVKKGY*" gene complement(233014..233895) /gene="glpQA" /locus_tag="BSU_02130" /old_locus_tag="BSU02130" downshifts complement(233025) /Source="Nicolas_upshifts" /id="D81" /incds=0 /nref=61 /ntot=107 /MaxReadThrough="2.31368" /MaxDrop="7.76277" /score="9.56390732" /energy="-11.4" /TU="NA" /idTUdmin="U147" /TUdmin=0 /isTUend="TRUE" upshifts complement(233938) /Source="Nicolas_upshifts" /id="U147" /multdbtbs="SigA" /comp="M6" /sig="Sig-" /pcomp="0.738261738261738" /psig="0.0999000999001" /xcortree=4 /SigmaFactorBS="tttaagaaagacacataaaaGATTAATagttttccAACACGC CGTTTACATCcgttttttattatgaaagacaggtagtgcttatctataaggaggagaa a" /listShort="glpQ" /GFF_Attribute="listLong" promotor_-10 complement(233947..233963) /Source="Nicolas_upshift_promotors" /id="U147" /multdbtbs="SigA" /comp="M6" /sig="Sig-" /pcomp="0.738261738261738" /psig="0.0999000999001" /xcortree=4 /SigmaFactorBS="tttaagaaagacacataaaaGATTAATagttttccAACACGC CGTTTACATCcgttttttattatgaaagacaggtagtgcttatctataaggaggagaa a" /listShort="glpQ" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 complement(233972..233978) /Source="Nicolas_upshift_promotors" /id="U147" /multdbtbs="SigA" /comp="M6" /sig="Sig-" /pcomp="0.738261738261738" /psig="0.0999000999001" /xcortree=4 /SigmaFactorBS="tttaagaaagacacataaaaGATTAATagttttccAACACGC CGTTTACATCcgttttttattatgaaagacaggtagtgcttatctataaggaggagaa a" /listShort="glpQ" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(233994..235328) /gene="glpT" /locus_tag="BSU_02140" /old_locus_tag="BSU02140" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:8012593, 11929549, 15849754, 16850406" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8012593, 11929549, 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="sn-glycerol-3-phosphate permease" /protein_id="NP_388096.1" /db_xref="EnsemblGenomes-Gn:BSU02140" /db_xref="EnsemblGenomes-Tr:CAB12008" /db_xref="GOA:P37948" /db_xref="InterPro:IPR000849" /db_xref="InterPro:IPR005267" /db_xref="InterPro:IPR011701" /db_xref="InterPro:IPR020846" /db_xref="InterPro:IPR021159" /db_xref="InterPro:IPR036259" /db_xref="SubtiList:BG10645" /db_xref="UniProtKB/Swiss-Prot:P37948" /translation="MLNIFKPAPHIERLDDSKMDAAYKRLRLQVFIGIFIGYAGYYLL RKNFAFAIPYLQEQGFSKTELGLVLAAVSIAYGFSKFIMGMVSDRCNPRYFLATGLFL SAIVNILFVSMPWVTSSVTIMFIFMFINGWFQGMGWPPCGRTMAHWFSISERGTKMSI WNVAHNIGGGILAPLVTLGIAMFVTWKSVFFFPAIIAIIISFLIVLLVRDTPQSCGLP PIEEYRNDYPKHAFKNQEKELTTKEILFQYVLNNKFLWYIAFANVFVYFVRYGVVDWA PTYLTEAKGFSPEDSRWSYFLYEYAGIPGTILCGWISDRFFKSRRAPAGVLFMAGVFI AVLVYWLNPAGNPLVDNIALISIGFLIYGPVMLIGLQAIDLAPKKAAGTAAGLTGFFG YIGGSAFANAIMGFVVDRFNWNGGFIMLISSCILAIVFLALTWNTGKRAEHV*" gene complement(233994..235328) /gene="glpT" /locus_tag="BSU_02140" /old_locus_tag="BSU02140" promotor_-35 234976..234985 /Source="Nicolas_upshift_promotors" /id="U148" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1339 /SigmaFactorBS="cgttgataaacataaaaataaacatgatggtgacgctcGAAG TCACCCaaggcattgaaaCGAATAGAATATTAACGATTgctgataaaaataggcctgt c" /listShort="S81, ybeF, ybfA" /GFF_Attribute="listLong" /label="promotor_-35" S_feature 234998..235624 /Source="Nicolas_S_feature" /locus_tag="new_234998_235624" /HighExp="S6, S8, S7, S5, BT, B36, G/S, C30, Pyr, B60" /AntisenseName="glpT" /AntisenseCor="-5.0958691169636701E-2" /AntisenseRegPval="-0.4" /CDS_PredictionProba="NA" /TUshortSig="SigK" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S81" promotor_-10 234998..235017 /Source="Nicolas_upshift_promotors" /id="U148" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1339 /SigmaFactorBS="cgttgataaacataaaaataaacatgatggtgacgctcGAAG TCACCCaaggcattgaaaCGAATAGAATATTAACGATTgctgataaaaataggcctgt c" /listShort="S81, ybeF, ybfA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 234998 /Source="Nicolas_upshifts" /id="U148" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1339 /SigmaFactorBS="cgttgataaacataaaaataaacatgatggtgacgctcGAAG TCACCCaaggcattgaaaCGAATAGAATATTAACGATTgctgataaaaataggcctgt c" /listShort="S81, ybeF, ybfA" /GFF_Attribute="listLong" S_feature complement(235329..235401) /Source="Nicolas_S_feature" /locus_tag="new_235329_235401_c" /HighExp="G150, Oxctl, Paraq, S0, Diami, H2O2, Lbexp, dia5, dia0, T0.30H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="Sig-, SigA" /TUshortPSig="0.042, 0.935" /TUlongSig="NA" /TUlongPSig="NA" /label="S82" promotor_no_box complement(235361..235461) /Source="Nicolas_upshift_promotors" /id="U149" /multdbtbs="-" /comp="M21" /sig="Sig-" /pcomp="0.370629370629371" /psig="0.041958041958042" /xcortree=1566 /SigmaFactorBS="tagcttggatggagatgaggagagccaggaatccaacccctt ttgacaaggggtgttttctggctctttttgtttttcgggaaaggaggcacgccacaca t" /listShort="S82, glpT, glpQ" /GFF_Attribute="listLong" /label="promotor_no_box" upshifts complement(235401) /Source="Nicolas_upshifts" /id="U149" /multdbtbs="-" /comp="M21" /sig="Sig-" /pcomp="0.370629370629371" /psig="0.041958041958042" /xcortree=1566 /SigmaFactorBS="tagcttggatggagatgaggagagccaggaatccaacccctt ttgacaaggggtgttttctggctctttttgtttttcgggaaaggaggcacgccacaca t" /listShort="S82, glpT, glpQ" /GFF_Attribute="listLong" S_feature complement(235403..235489) /Source="Nicolas_S_feature" /locus_tag="new_235403_235489_c" /HighExp="G150, Oxctl, S0, Diami, Lbexp, dia5, Paraq, dia0, T0.30H, H2O2" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.935" /TUlongSig="NA" /TUlongPSig="NA" /label="S83" promotor_-10 complement(235479..235498) /Source="Nicolas_upshift_promotors" /id="U150" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.396603396603397" /psig="0.935064935064935" /xcortree=1567 /SigmaFactorBS="tattcacttccctaaggcccaatttgaaaattaccCGTTTAC AttcgctccggacTATGATAATTTAAGAAAGCGctatcatgataagttaatagcttgg a" /listShort="S83, S82, glpT, glpQ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(235493) /Source="Nicolas_upshifts" /id="U150" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.396603396603397" /psig="0.935064935064935" /xcortree=1567 /SigmaFactorBS="tattcacttccctaaggcccaatttgaaaattaccCGTTTAC AttcgctccggacTATGATAATTTAAGAAAGCGctatcatgataagttaatagcttgg a" /listShort="S83, S82, glpT, glpQ" /GFF_Attribute="listLong" promotor_-35 complement(235511..235518) /Source="Nicolas_upshift_promotors" /id="U150" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.396603396603397" /psig="0.935064935064935" /xcortree=1567 /SigmaFactorBS="tattcacttccctaaggcccaatttgaaaattaccCGTTTAC AttcgctccggacTATGATAATTTAAGAAAGCGctatcatgataagttaatagcttgg a" /listShort="S83, S82, glpT, glpQ" /GFF_Attribute="listLong" /label="promotor_-35" CDS 235625..235873 /gene="ybeF" /locus_tag="BSU_02150" /old_locus_tag="BSU02150" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_388097.1" /db_xref="EnsemblGenomes-Gn:BSU02150" /db_xref="EnsemblGenomes-Tr:CAB12009" /db_xref="GOA:O31442" /db_xref="InterPro:IPR020258" /db_xref="SubtiList:BG12731" /db_xref="UniProtKB/Swiss-Prot:O31442" /translation="MDELDIAFFILPLGIMLLSIVGTCICKNPYLMPMLSLVISLVLT FTIFNQSFLGWAVVYSLVSLALSYITLIVVRKRKESGN*" gene 235625..235873 /gene="ybeF" /locus_tag="BSU_02150" /old_locus_tag="BSU02150" promotor_-35 235897..235904 /Source="Nicolas_upshift_promotors" /id="U151" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.801198801198801" /psig="0.984015984015984" /xcortree=3080 /SigmaFactorBS="gtaaggaaaaggaaggaatcaggaaattaaaaagacctcact ttctaacatatCGTTGACTaaagcaactatatgtGATTATAATTGCTTTAGTCAacga t" /listShort="ybfA, ybfB" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 235904 /Source="Nicolas_upshifts" /id="U151" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.801198801198801" /psig="0.984015984015984" /xcortree=3080 /SigmaFactorBS="gtaaggaaaaggaaggaatcaggaaattaaaaagacctcact ttctaacatatCGTTGACTaaagcaactatatgtGATTATAATTGCTTTAGTCAacga t" /listShort="ybfA, ybfB" /GFF_Attribute="listLong" promotor_-10 235920..235939 /Source="Nicolas_upshift_promotors" /id="U151" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.801198801198801" /psig="0.984015984015984" /xcortree=3080 /SigmaFactorBS="gtaaggaaaaggaaggaatcaggaaattaaaaagacctcact ttctaacatatCGTTGACTaaagcaactatatgtGATTATAATTGCTTTAGTCAacga t" /listShort="ybfA, ybfB" /GFF_Attribute="listLong" /label="promotor_-10" CDS 235965..236882 /gene="ybfA" /locus_tag="BSU_02160" /old_locus_tag="BSU02160" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative transcriptional regulator with acetyltransferase domain" /protein_id="NP_388098.1" /db_xref="EnsemblGenomes-Gn:BSU02160" /db_xref="EnsemblGenomes-Tr:CAB12010" /db_xref="GOA:O31443" /db_xref="InterPro:IPR000182" /db_xref="InterPro:IPR000835" /db_xref="InterPro:IPR016181" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG12732" /db_xref="UniProtKB/Swiss-Prot:O31443" /translation="MKTRESSVGLKFRKFNRFYTNVLGFLNEHIYDSPFSLTETRILF EIYNTPNCTAKALQDKLGLDRGYVSRIVKQFEKEDLIYKQRSKDDARHHYIFVTETGK TIYKKLEEKANEQVELMLKVINQKEQHKLAEAMAEIEAILSQSLSARASEISIRDYFL SEDLQLLIEKQRQFYAEAHGWDDTFLAYLQETFDADIEKIWIAESGGKFAGSVGLVKH DEKTVQLRWFLVDADFRGRGLGTQLLEHLVAYCQDMKFDRIFLWTVSTMAEARPLYKK FGFRISEVKQEAPLWGQQLTEERWDLELS*" gene 235965..236882 /gene="ybfA" /locus_tag="BSU_02160" /old_locus_tag="BSU02160" CDS 236879..238129 /gene="ybfB" /locus_tag="BSU_02170" /old_locus_tag="BSU02170" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative carboxylate transporter" /protein_id="NP_388099.1" /db_xref="EnsemblGenomes-Gn:BSU02170" /db_xref="EnsemblGenomes-Tr:CAB12011" /db_xref="GOA:O31444" /db_xref="InterPro:IPR011701" /db_xref="InterPro:IPR020846" /db_xref="InterPro:IPR036259" /db_xref="SubtiList:BG12733" /db_xref="UniProtKB/Swiss-Prot:O31444" /translation="MKRLHYAWIIVSVTFLILLAVQGVRLSFGAFVEPWERQFSIDRS TISLISTVSFIVYGISQPVIGRLVDKWGARAVLAWSALLTGVSIFLTYLVTSPWQLFL LYGLGVSLGVGGASNVAASVLVVNWFSKKRGLAFGIMEAGFGAGQMLLVPGSLMLIHW FSWKLTVVVLGLLLIVIVFPAALLMLRNNPSEKNTEPIGGLAASEKETAPKTTALSVA GMFRMRQFWFLIFPFLICGFTTVGLMDTHLIPFSHDHGFSTTVTSAAVSLLAGFNIAG ILLSGIVADRWSSRKILCILYAVRALSIVILIYSHEPYLLLAFAILFGLVDFATVAPT QMLATQYFQNYSIGLMIGWLSLAHQIGSALGAYVPGVIYTVTGEYTLAFYLSIGMLVL ASVMNVMLREPAAVTRDSAAVVDK*" gene 236879..238129 /gene="ybfB" /locus_tag="BSU_02170" /old_locus_tag="BSU02170" downshifts 238119 /Source="Nicolas_upshifts" /id="D82" /incds=0 /nref=57 /ntot=187 /MaxReadThrough="1.17226" /MaxDrop="5.55429" /score="12.1347284" /energy="-9.5" /TU="NA" /idTUdmin="U151" /TUdmin=0 /isTUend="TRUE" CDS complement(238164..238448) /gene="ybfEc" /locus_tag="BSU_02180" /old_locus_tag="BSU02180" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /pseudo /codon_start=1 /transl_table=11 /product="conserved protein of unknown function (C-terminal end)" /db_xref="EnsemblGenomes-Gn:BSU02180" /db_xref="EnsemblGenomes-Tr:CAB12012" /db_xref="GOA:O31445" /db_xref="PSEUDO:CAB12012.2" /db_xref="SubtiList:BG12734" /db_xref="UniProtKB/Swiss-Prot:O31445" /translation="MNHCLHSNTLAKIVCTVTLITLYFYFFSTRFNELIELAVQMFFA LIGLFWVFIVSPFSRKVQISERFKQKSENARIVGMIDFVLEQKYKKSISE*" gene complement(238164..238448) /gene="ybfEc" /locus_tag="BSU_02180" /old_locus_tag="BSU02180" /pseudo downshifts complement(238217) /Source="Nicolas_upshifts" /id="D83" /incds=0 /nref=4 /ntot=189 /MaxReadThrough="2.49989" /MaxDrop="3.7302" /score="13.7144473" /energy="-12.6" /TU="U153" /idTUdmin="U153" /TUdmin="-22" /isTUend="TRUE" CDS complement(238354..238476) /gene="ybfEn" /locus_tag="BSU_02181" /old_locus_tag="BSU02181" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /pseudo /codon_start=1 /transl_table=11 /product="conserved protein of unknown function YbfE (N-terminal fragment)" /db_xref="PSEUDO:SOX90538.1" /translation="MLNQLKVFFSEPLLTFKHTCQNRMYCDINNVILLFFQHSF*" gene complement(238354..238476) /gene="ybfEn" /locus_tag="BSU_02181" /old_locus_tag="BSU02181" /pseudo S_feature complement(238449..238569) /Source="Nicolas_S_feature" /locus_tag="new_238449_238569_c" /HighExp="Lbexp, dia0, LBGexp, G150, Mt0, H2O2, dia5, M0t45, G135, HPh" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigEF, Sig-" /TUshortPSig="0.899, 0" /TUlongSig="NA" /TUlongPSig="NA" /label="S84" promotor_-10 complement(238554..238572) /Source="Nicolas_upshift_promotors" /id="U152" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.899100899100899" /psig="0.899100899100899" /xcortree=1463 /SigmaFactorBS="tactaagaaatactcaatttttatactttaagagaTGTATAt attgaatgtagaccaCCATACATATAAAGAAACAgaaacagcaactttattttagaac a" /listShort="S84, ybfE" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(238569) /Source="Nicolas_upshifts" /id="U152" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.899100899100899" /psig="0.899100899100899" /xcortree=1463 /SigmaFactorBS="tactaagaaatactcaatttttatactttaagagaTGTATAt attgaatgtagaccaCCATACATATAAAGAAACAgaaacagcaactttattttagaac a" /listShort="S84, ybfE" /GFF_Attribute="listLong" S_feature complement(238571..238643) /Source="Nicolas_S_feature" /locus_tag="new_238571_238643_c" /HighExp="Lbexp, dia0, LBGexp, HPh, G150, H2O2, dia5, Mt0, M0t45, G180" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="Sig-" /TUshortPSig=0 /TUlongSig="NA" /TUlongPSig="NA" /label="S85" promotor_-35 complement(238589..238594) /Source="Nicolas_upshift_promotors" /id="U152" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.899100899100899" /psig="0.899100899100899" /xcortree=1463 /SigmaFactorBS="tactaagaaatactcaatttttatactttaagagaTGTATAt attgaatgtagaccaCCATACATATAAAGAAACAgaaacagcaactttattttagaac a" /listShort="S84, ybfE" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(238644..239555) /gene="ybfF" /locus_tag="BSU_02190" /old_locus_tag="BSU02190" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_388101.1" /db_xref="EnsemblGenomes-Gn:BSU02190" /db_xref="EnsemblGenomes-Tr:CAB12013" /db_xref="GOA:O31446" /db_xref="SubtiList:BG12735" /db_xref="UniProtKB/Swiss-Prot:O31446" /translation="MKNDQIVFEKTKNIAHDINQMQNQQEIIDYLFRQDSLTLNQLKH YYSEPSLPLQFLVKVAVLCMFISMTLASFLFIQAKEVFTNTILSDISPAVFSIFTVIC IFMTYTKIIKKGNKNKGKASLNQRSEFYEKNKLINTILYKKYKMDQQNIQANKHTASD NEDSMNFSAVLNHVLTISKNDKELLGYLDTRDNAMLSQLKAYFSTRPFSLPHYMSLMF CGSIIVVYATSLFSGQINYIDIPHIFIFLLLIIFLKILIDLIKLLNISRKGQLHTVLH FAQRAEYLRMRGVIDFILTERYNKKIM*" gene complement(238644..239555) /gene="ybfF" /locus_tag="BSU_02190" /old_locus_tag="BSU02190" S_feature complement(239556..239643) /Source="Nicolas_S_feature" /locus_tag="new_239556_239643_c" /HighExp="LBGexp, Lbexp, G150, dia5, dia0, G135, Oxctl, H2O2, Mt0, Salt" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="Sig-" /TUshortPSig=0 /TUlongSig="NA" /TUlongPSig="NA" /label="S86" CDS complement(239644..241842) /gene="ybfG" /locus_tag="BSU_02200" /old_locus_tag="BSU02200" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative pepdidoglycan binding protein" /protein_id="NP_388102.1" /db_xref="EnsemblGenomes-Gn:BSU02200" /db_xref="EnsemblGenomes-Tr:CAB12014" /db_xref="GOA:O31447" /db_xref="InterPro:IPR002477" /db_xref="InterPro:IPR015020" /db_xref="InterPro:IPR017853" /db_xref="InterPro:IPR036365" /db_xref="InterPro:IPR036366" /db_xref="SubtiList:BG12736" /db_xref="UniProtKB/Swiss-Prot:O31447" /translation="MVDEMVLITQQWLNDTYSGKHGYNPVEESGKTGWDTIYGLTRAL QIELGISEPADNFGPTTQRLFKPLKRQAPDSKPSNMNFILQGALWCKGFNPGGFTGVF YEKTENAVKEFQKAAGLTTQDGIVTTLIMKALLDMSAFKLVSGGDSRIRQIQQNLNRD YNDYIGLMPCDGLYGRDTNKALIYALQKEEGMSTSVANGFFGNGTTSLCPTLTPGDSR TGFVLIVQYALYCNGKSFDPGEFDGKYGVGVVSAVKAFQEFMCLPQTGYADMPTIKAL LSSSGDTTRTASACDTATIITAEKAQTLRNNGYKTVGRYLTGNVRTSSGLTSKALTSK ELAVILDAGLKVFPIYQDGGYESSYFVKDQGTRDAYSAASAARRLGFPSGTTIYFAVD FDAYDYEVTDKIIPYFQEIKSAFTKMQTFSTAPKYEIGVYGPRNICIRTSEAGLTKYS FVANMSTGFSGNLGYPMPNNWAFDQFYEGTIGSGSGSIGIDKDGYSGRDSGASNVNPP SDPVYDARLRTLTDILSTIPALENLTSLANAMFEFDTTETIFTSPELDIILSTSLLAT IPSEGSPNTITITNGKPGAYITGLLGDTQTSLTASQIDSYQNLLNSLSLSVRNGYLEV YVNPTAESLNIQIKIYTPDIPVGDNVTTGLTTTITFKIKTYKGVPVTSPESELALDWP SYDQYLFPVVGVAALLLIGNMGSDLTNNKGVKVATALSAMLLAIFAYYTS*" gene complement(239644..241842) /gene="ybfG" /locus_tag="BSU_02200" /old_locus_tag="BSU02200" misc_feature complement(241877..241895) /Source="Nicolas_upshift_promotors" /id="U153" /multdbtbs="-" /comp="M12" /sig="Sig-" /pcomp=1 /psig=0 /xcortree=1523 /SigmaFactorBS="ctgttggagaacggatgtaaaatggatgcttaacggcatcca tttttttattttGTCCTACGTTTGCCACCTAtaaatgaacgcaatctaacaaaggagg a" /listShort="ybfG, S86, ybfF, S85, S84, ybfE" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(241889) /Source="Nicolas_upshifts" /id="U153" /multdbtbs="-" /comp="M12" /sig="Sig-" /pcomp=1 /psig=0 /xcortree=1523 /SigmaFactorBS="ctgttggagaacggatgtaaaatggatgcttaacggcatcca tttttttattttGTCCTACGTTTGCCACCTAtaaatgaacgcaatctaacaaaggagg a" /listShort="ybfG, S86, ybfF, S85, S84, ybfE" /GFF_Attribute="listLong" CDS complement(241917..242837) /gene="ybfH" /locus_tag="BSU_02210" /old_locus_tag="BSU02210" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative permease" /protein_id="NP_388103.1" /db_xref="EnsemblGenomes-Gn:BSU02210" /db_xref="EnsemblGenomes-Tr:CAB12015" /db_xref="GOA:O31448" /db_xref="InterPro:IPR000620" /db_xref="SubtiList:BG12737" /db_xref="UniProtKB/Swiss-Prot:O31448" /translation="MNIQRETSGHIAAIVTILIWGTTFISTKVLLADFSPMEILFYRF LMGFIALILVRPNMIPFRNWRQELLFAGAGLFGVTLYFLLENIALTYTYASNVGMIVS IIPMITAVLAHFLLEGEKLRLTFLIGFISALIGLLLITFNGNVVLRLNPLGDIMAAGA ALVFGGYSIFMKKLSAYEYHIIELTQRVFLYGLLFMVPALFLFDFHFDLSRFSSASNI LNMLFLGIGASALCFATWNYSVGVLGAVKSSAYIYMVPVITIAASVLILHENMTWIAL LGGALTLLGLYISELKPKAKLLENGCKMDA*" gene complement(241917..242837) /gene="ybfH" /locus_tag="BSU_02210" /old_locus_tag="BSU02210" CDS complement(242834..243661) /gene="ybfI" /locus_tag="BSU_02220" /old_locus_tag="BSU02220" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative transcriptional regulator (AraC/XylS family, cupin family)" /protein_id="NP_388104.1" /db_xref="EnsemblGenomes-Gn:BSU02220" /db_xref="EnsemblGenomes-Tr:CAB12016" /db_xref="GOA:O31449" /db_xref="InterPro:IPR003313" /db_xref="InterPro:IPR009057" /db_xref="InterPro:IPR018060" /db_xref="SubtiList:BG12738" /db_xref="UniProtKB/Swiss-Prot:O31449" /translation="MQNETRTLQLDPHLHIEAYRFKGIMQKFPNHFHDYYVIGFIEKG QRYLACQDQEYIINPGDLLLFNPRDTHSCEQIDGRTLDYRCINVMPDIMEKAVKEITG SGHLPYFSQHVLFRHELTASLQELHILISEEKQALRKEELFLHLLEELIRHYSDVTFL SSVPEPSDEVKMVCEFLEEHYAENVTLNDLSELTGWSKYHLLRSFTKQKGITPNSYME TIRINQAKKLLEQGVRPIDAAFQTGFSDQSHMTKFFKRQVGLTPKQYMKIFEKELHR* " gene complement(242834..243661) /gene="ybfI" /locus_tag="BSU_02220" /old_locus_tag="BSU02220" misc_feature complement(243688..243707) /Source="Nicolas_upshift_promotors" /id="U154" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.992007992007992" /psig="0.999000999001" /xcortree=583 /SigmaFactorBS="ctttctctattcctaaacagcaacatcatacaagaaatcccc caaaatCATGCTACACTTAATCCAAGaccaccacaccgacaggaggcatcccatgcaa a" /listShort="ybfI" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(243695) /Source="Nicolas_upshifts" /id="U154" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.992007992007992" /psig="0.999000999001" /xcortree=583 /SigmaFactorBS="ctttctctattcctaaacagcaacatcatacaagaaatcccc caaaatCATGCTACACTTAATCCAAGaccaccacaccgacaggaggcatcccatgcaa a" /listShort="ybfI" /GFF_Attribute="listLong" promotor_-35 243835..243838 /Source="Nicolas_upshift_promotors" /id="U155" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.767232767232767" /psig="0.999000999001" /xcortree=2313 /SigmaFactorBS="tttaaccctcaataataattttatcttttttaataaaAATTt atttttcaaatatTTCAGTTATAATGGTTTGGAacagataggaggggcaaagatgtat c" /listShort="purT" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 243853..243872 /Source="Nicolas_upshift_promotors" /id="U155" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.767232767232767" /psig="0.999000999001" /xcortree=2313 /SigmaFactorBS="tttaaccctcaataataattttatcttttttaataaaAATTt atttttcaaatatTTCAGTTATAATGGTTTGGAacagataggaggggcaaagatgtat c" /listShort="purT" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 243858 /Source="Nicolas_upshifts" /id="U155" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.767232767232767" /psig="0.999000999001" /xcortree=2313 /SigmaFactorBS="tttaaccctcaataataattttatcttttttaataaaAATTt atttttcaaatatTTCAGTTATAATGGTTTGGAacagataggaggggcaaagatgtat c" /listShort="purT" /GFF_Attribute="listLong" CDS 243892..245046 /gene="purT" /locus_tag="BSU_02230" /old_locus_tag="BSU02230" /EC_number="2.1.2.-" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:7496533" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7496533; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="phosphoribosylglycinamide formyltransferase 2" /protein_id="NP_388105.1" /db_xref="EnsemblGenomes-Gn:BSU02230" /db_xref="EnsemblGenomes-Tr:CAB12017" /db_xref="GOA:P39771" /db_xref="InterPro:IPR003135" /db_xref="InterPro:IPR005862" /db_xref="InterPro:IPR011054" /db_xref="InterPro:IPR011761" /db_xref="InterPro:IPR013815" /db_xref="InterPro:IPR016185" /db_xref="SubtiList:BG10924" /db_xref="UniProtKB/Swiss-Prot:P39771" /translation="MYQSKKVLLLGSGELGKEVVIEAQRLGVQTVAVDSYEHAPAMQV AHNSYVVDMLDPEQIRTIIEKENPDLIVPEVEAIATDELLKLEEEGFHVIPNARAAKL TMDREGIRRLAAETLGLATAGYEFANTYDEFIQAAAQIGFPCVVKPLMSSSGKGQSVC RSEADLESCWETAMEGGRVKNGRVIVEEFIPFESEITLLTVRAVNGTAFCEPIGHVQK DGDYIESWQPHDMTEQQIEEAKHIAKTITDELGGYGLFGVELFLAKDRVYFSEVSPRP HDTGLVTLVTQNLSEFALHVRAILGFPITEITQLSPGASRPLKAPEELADYTVEGLEN ALAVPKTQVRVFGKPITKAGRRMAVALSAADSVETARENAKKALDQLILK*" gene 243892..245046 /gene="purT" /locus_tag="BSU_02230" /old_locus_tag="BSU02230" downshifts 245027 /Source="Nicolas_upshifts" /id="D84" /incds=0 /nref=100 /ntot=189 /MaxReadThrough="2.6996" /MaxDrop="5.22319" /score="39.2561117" /energy="-15.1" /TU="NA" /idTUdmin="U155" /TUdmin=0 /isTUend="TRUE" promotor_-35 245107..245112 /Source="Nicolas_upshift_promotors" /id="U156" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.973026973026973" /psig="0.973026973026973" /xcortree=1104 /SigmaFactorBS="ttgtcatgggacaaggcctgtttttttctttctccgtaaaag ttttATCATAagaatcagaaacctGATTATAATGTAAAAGTCTtccatcgatacgggt g" /listShort="mpr, ybfJ" /listLong="S87, ybfK, S88, pssA, ybfM, psd" /label="promotor_-35" upshifts 245121 /Source="Nicolas_upshifts" /id="U156" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.973026973026973" /psig="0.973026973026973" /xcortree=1104 /SigmaFactorBS="ttgtcatgggacaaggcctgtttttttctttctccgtaaaag ttttATCATAagaatcagaaacctGATTATAATGTAAAAGTCTtccatcgatacgggt g" /listShort="mpr, ybfJ" /listLong="S87, ybfK, S88, pssA, ybfM, psd" promotor_-10 245127..245145 /Source="Nicolas_upshift_promotors" /id="U156" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.973026973026973" /psig="0.973026973026973" /xcortree=1104 /SigmaFactorBS="ttgtcatgggacaaggcctgtttttttctttctccgtaaaag ttttATCATAagaatcagaaacctGATTATAATGTAAAAGTCTtccatcgatacgggt g" /listShort="mpr, ybfJ" /listLong="S87, ybfK, S88, pssA, ybfM, psd" /label="promotor_-10" promotor_-35 245161..245168 /Source="Nicolas_upshift_promotors" /id="U157" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.390609390609391" /psig=1 /xcortree=760 /SigmaFactorBS="acctgattataatgtaaaagtcttccatcgatacgggtGGTT GACActaaaggagggagaTGACAAAATGAAATTAGTTCcaagattcagaaaacaatgg t" /listShort="mpr, ybfJ" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 245183..245202 /Source="Nicolas_upshift_promotors" /id="U157" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.390609390609391" /psig=1 /xcortree=760 /SigmaFactorBS="acctgattataatgtaaaagtcttccatcgatacgggtGGTT GACActaaaggagggagaTGACAAAATGAAATTAGTTCcaagattcagaaaacaatgg t" /listShort="mpr, ybfJ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 245183 /Source="Nicolas_upshifts" /id="U157" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.390609390609391" /psig=1 /xcortree=760 /SigmaFactorBS="acctgattataatgtaaaagtcttccatcgatacgggtGGTT GACActaaaggagggagaTGACAAAATGAAATTAGTTCcaagattcagaaaacaatgg t" /listShort="mpr, ybfJ" /GFF_Attribute="listLong" CDS 245190..246131 /gene="mpr" /locus_tag="BSU_02240" /old_locus_tag="BSU02240" /EC_number="3.4.21.-" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1c: Function from experimental evidences in the studied genus; PubMedId: 15205417, 15375126, 21819557, 25666135; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="extracellular glutamyl-endopeptidase" /protein_id="NP_388106.1" /db_xref="EnsemblGenomes-Gn:BSU02240" /db_xref="EnsemblGenomes-Tr:CAB12018" /db_xref="GOA:P39790" /db_xref="InterPro:IPR000126" /db_xref="InterPro:IPR001254" /db_xref="InterPro:IPR008256" /db_xref="InterPro:IPR009003" /db_xref="InterPro:IPR018114" /db_xref="InterPro:IPR028301" /db_xref="SubtiList:BG10690" /db_xref="UniProtKB/Swiss-Prot:P39790" /translation="MKLVPRFRKQWFAYLTVLCLALAAAVSFGVPAKAAENPQTSVSN TGKEADATKNQTSKADQVSAPYEGTGKTSKSLYGGQTELEKNIQTLQPSSIIGTDERT RISSTTSFPYRATVQLSIKYPNTSSTYGCTGFLVNPNTVVTAGHCVYSQDHGWASTIT AAPGRNGSSYPYGTYSGTMFYSVKGWTESKDTNYDYGAIKLNGSPGNTVGWYGYRTTN SSSPVGLSSSVTGFPCDKTFGTMWSDTKPIRSAETYKLTYTTDTYGCQSGSPVYRNYS DTGQTAIAIHTNGGSSYNLGTRVTNDVFNNIQYWANQ*" gene 245190..246131 /gene="mpr" /locus_tag="BSU_02240" /old_locus_tag="BSU02240" CDS 246094..246492 /gene="ybfJ" /locus_tag="BSU_02250" /old_locus_tag="BSU02250" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type lp: lipoprotein" /codon_start=1 /transl_table=11 /product="putative lipoprotein" /protein_id="NP_388107.1" /db_xref="EnsemblGenomes-Gn:BSU02250" /db_xref="EnsemblGenomes-Tr:CAB12019" /db_xref="InterPro:IPR013783" /db_xref="InterPro:IPR019730" /db_xref="SubtiList:BG12739" /db_xref="UniProtKB/Swiss-Prot:O31451" /translation="MYSTIFNIGQINKYSKLAIFMSILFLCGCSSQTHSSQKETTIPV TLHVEDAKGLPVEGVQVTIVKAPSSDEEPSTEIGEILGKTDKNGDIKWDTGRKGDYSV ALTKGETSVTHHISLTEDKKDHAIPLVFKE*" gene 246094..246492 /gene="ybfJ" /locus_tag="BSU_02250" /old_locus_tag="BSU02250" promotor_-10 complement(246186..246200) /Source="Nicolas_upshift_promotors" /id="U158" /multdbtbs="-" /comp="M1" /sig="Sig-" /pcomp="0.418581418581419" /psig="0.418581418581419" /xcortree=776 /SigmaFactorBS="gcagccccttagcatcctccacatgaagagtgacaGGAATAg tcgtttctttttgaGAAGAATGCGTCTGCgaactgcacccgcataaaaacaaaataga c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(246196) /Source="Nicolas_upshifts" /id="U158" /multdbtbs="-" /comp="M1" /sig="Sig-" /pcomp="0.418581418581419" /psig="0.418581418581419" /xcortree=776 /SigmaFactorBS="gcagccccttagcatcctccacatgaagagtgacaGGAATAg tcgtttctttttgaGAAGAATGCGTCTGCgaactgcacccgcataaaaacaaaataga c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(246216..246221) /Source="Nicolas_upshift_promotors" /id="U158" /multdbtbs="-" /comp="M1" /sig="Sig-" /pcomp="0.418581418581419" /psig="0.418581418581419" /xcortree=776 /SigmaFactorBS="gcagccccttagcatcctccacatgaagagtgacaGGAATAg tcgtttctttttgaGAAGAATGCGTCTGCgaactgcacccgcataaaaacaaaataga c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 246479 /Source="Nicolas_upshifts" /id="D85" /incds=0 /nref=19 /ntot=51 /MaxReadThrough="3.50775" /MaxDrop="5.06025" /score="29.4582027" /energy="-15.4" /TU="U156" /idTUdmin="U157" /TUdmin=0 /isTUend="TRUE" promotor_-35 246548..246555 /Source="Nicolas_upshift_promotors" /id="U159" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.833166833166833" /psig=1 /xcortree=2185 /SigmaFactorBS="ttttatttattgcaggaaaccaaacTATATACTggaaattta ttatgTGAGATAATAAGAAATAGGTattttttcttacgagacaaaaggggcgttatcc t" /listShort="S87, ybfK, S88, pssA, ybfM, psd" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 246570..246589 /Source="Nicolas_upshift_promotors" /id="U159" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.833166833166833" /psig=1 /xcortree=2185 /SigmaFactorBS="ttttatttattgcaggaaaccaaacTATATACTggaaattta ttatgTGAGATAATAAGAAATAGGTattttttcttacgagacaaaaggggcgttatcc t" /listShort="S87, ybfK, S88, pssA, ybfM, psd" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 246583..246657 /Source="Nicolas_S_feature" /locus_tag="new_246583_246657" /HighExp="Cold, LoTm, S0, aero, ferm, T-4.40H, nit, T-5.40H, T-0.40H, Paraq" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="SigEF" /TUlongPSig="0.973" /label="S87" upshifts 246583 /Source="Nicolas_upshifts" /id="U159" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.833166833166833" /psig=1 /xcortree=2185 /SigmaFactorBS="ttttatttattgcaggaaaccaaacTATATACTggaaattta ttatgTGAGATAATAAGAAATAGGTattttttcttacgagacaaaaggggcgttatcc t" /listShort="S87, ybfK, S88, pssA, ybfM, psd" /GFF_Attribute="listLong" CDS 246658..247548 /gene="cesB" /locus_tag="BSU_02260" /old_locus_tag="BSU02260" /EC_number="3.1.1.1" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:11389736, 24418394" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11389736, 24418394; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="enantioselective carboxylesterase" /protein_id="NP_388108.1" /db_xref="EnsemblGenomes-Gn:BSU02260" /db_xref="EnsemblGenomes-Tr:CAB12020" /db_xref="GOA:O31452" /db_xref="InterPro:IPR000073" /db_xref="InterPro:IPR029058" /db_xref="PDB:4CCY" /db_xref="SubtiList:BG12740" /db_xref="UniProtKB/Swiss-Prot:O31452" /translation="MIQDSMQFAAVESGLRFYQAYDQSLSLWPIESEAFYVSTRFGKT HIIASGPKDAPSLILLHGGLFSSAMWYPNIAAWSSQFRTYAVDIIGDKNKSIPSAAME TRADFAEWMKDVFDSLGLETAHLAGLSLGGSHIVNFLLRAPERVERAVVISPAEAFIS FHPDVYKYAAELTGARGAESYIKWITGDSYDLHPLLQRQIVAGVEWQDEQRSLKPTEN GFPYVFTDQELKSIQVPVLLMFGEHEAMYHQQMAFERASVLVPGIQAEIVKNAGHLLS LEQPEYVNQRVLSFLCGGIK*" gene 246658..247548 /gene="cesB" /locus_tag="BSU_02260" /old_locus_tag="BSU02260" promotor_-35 246892..246899 /Source="Nicolas_upshift_promotors" /id="U160" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp="0.867132867132867" /psig="0.867132867132867" /xcortree=2736 /SigmaFactorBS="ttttcagctctgcgatgtggtatccgaatatcgcagcgtgga gcAGTCAATTtcgtacatatgcgGTCGATATAATAGGAGACAaaaataaaagtatacc a" /listShort="S88, pssA, ybfM, psd" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 246908 /Source="Nicolas_upshifts" /id="U160" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp="0.867132867132867" /psig="0.867132867132867" /xcortree=2736 /SigmaFactorBS="ttttcagctctgcgatgtggtatccgaatatcgcagcgtgga gcAGTCAATTtcgtacatatgcgGTCGATATAATAGGAGACAaaaataaaagtatacc a" /listShort="S88, pssA, ybfM, psd" /GFF_Attribute="listLong" promotor_-10 246913..246931 /Source="Nicolas_upshift_promotors" /id="U160" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp="0.867132867132867" /psig="0.867132867132867" /xcortree=2736 /SigmaFactorBS="ttttcagctctgcgatgtggtatccgaatatcgcagcgtgga gcAGTCAATTtcgtacatatgcgGTCGATATAATAGGAGACAaaaataaaagtatacc a" /listShort="S88, pssA, ybfM, psd" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 247549..247743 /Source="Nicolas_S_feature" /locus_tag="new_247549_247743" /HighExp="Cold, LBGstat, Paraq, Oxctl, H2O2, dia15, G135, Diami, Lbexp, LBGexp" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigD, SigA" /TUshortPSig="0.867, 1" /TUlongSig="SigEF" /TUlongPSig="0.973" /label="S88" CDS 247744..248277 /gene="pssA" /locus_tag="BSU_02270" /old_locus_tag="BSU02270" /EC_number="2.7.8.8" /function="16.13: Shape" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:12682299, 14762009, 15743965, 15849754, 16850406" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12682299, 14762009, 15743965, 15849754, 16850406; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="phosphatidylserine synthase" /protein_id="NP_388109.1" /db_xref="EnsemblGenomes-Gn:BSU02270" /db_xref="EnsemblGenomes-Tr:CAB12021" /db_xref="GOA:P39823" /db_xref="InterPro:IPR000462" /db_xref="InterPro:IPR004533" /db_xref="SubtiList:BG11012" /db_xref="UniProtKB/Swiss-Prot:P39823" /translation="MNYIPCMITIGNFICGLLAIHSLLYHNIHSAVLFIFTGMFLDFF DGMAARKLNAVSDMGRELDSFADLVTFGVAPSMLAYSVALYTLPFIGILCALTYSICG MLRLSKFNIEQSKLPTFIGMPIPFAGMCLVILSFTYNPILLAIGTCGLSYLMVSKIKF PHFKKHAAENLESGRWN*" gene 247744..248277 /gene="pssA" /locus_tag="BSU_02270" /old_locus_tag="BSU02270" CDS 248268..248756 /gene="ybfM" /locus_tag="BSU_02280" /old_locus_tag="BSU02280" /function="16.8: Protect" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 12682299, 14762009, 15849754, 16850406; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative membrane phosphatase" /protein_id="NP_388110.1" /db_xref="EnsemblGenomes-Gn:BSU02280" /db_xref="EnsemblGenomes-Tr:CAB12022" /db_xref="GOA:O31453" /db_xref="InterPro:IPR032816" /db_xref="SubtiList:BG12741" /db_xref="UniProtKB/Swiss-Prot:O31453" /translation="MELVQQLIADYGYLAIFLMLVLGIVGLPIPDEVMMTVVGYFTHT DVLNYELSILISFVGALLGMLISYMIGRKAGRPFIDKYGKWVGLKEKRMMKVEKWMKK YGPYSLILGYFIPGVRHVTCYFSGIGKMDLKTYVAFAAIGAFLWCFVFITIGRVIGII HV*" gene 248268..248756 /gene="ybfM" /locus_tag="BSU_02280" /old_locus_tag="BSU02280" CDS 248749..249540 /gene="psd" /locus_tag="BSU_02290" /old_locus_tag="BSU02290" /EC_number="4.1.1.65" /function="16.2: Construct biomass (Anabolism)" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:12682299, 14762009, 9422599" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12682299, 14762009, 9422599; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="phosphatidylserine decarboxylase; 32 kDa precursor processed into a 29 kDa protein" /protein_id="NP_388111.1" /db_xref="EnsemblGenomes-Gn:BSU02290" /db_xref="EnsemblGenomes-Tr:CAB12023" /db_xref="GOA:P39822" /db_xref="InterPro:IPR003817" /db_xref="InterPro:IPR033177" /db_xref="InterPro:IPR033178" /db_xref="SubtiList:BG11013" /db_xref="UniProtKB/Swiss-Prot:P39822" /translation="MFNTAVKILYRSLIELTNHRLSSYLIKGFCESKISKPVIPLFSK HFRLNWDDVDGTAADYGSLSELFIRQINLERRPVSKEAHAVVSPVDGVVQTVGIINPN QTFTVKGKDYSFAELTGCKSADHQYNGGYFVVLYLSPRHYHRFHSPISCRYQKLAELG NRSYPVNQLGLKYGKDVLSKNYRFVYELNSGSRNVLMIPVGAMNINSIVQTNTRTELE IGEELGYFSFGSTVILVFEKDAFQPSAHLAEGQEVQVGELIGYEE*" gene 248749..249540 /gene="psd" /locus_tag="BSU_02290" /old_locus_tag="BSU02290" downshifts 249515 /Source="Nicolas_upshifts" /id="D86" /incds=0 /nref=101 /ntot=236 /MaxReadThrough="3.18138" /MaxDrop="4.25536" /score="-2.98360164" /energy="-8" /TU="U159" /idTUdmin="U160" /TUdmin=0 /isTUend="TRUE" CDS 249595..249873 /gene="ybfN" /locus_tag="BSU_02300" /old_locus_tag="BSU02300" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_388112.1" /db_xref="EnsemblGenomes-Gn:BSU02300" /db_xref="EnsemblGenomes-Tr:CAB12024" /db_xref="SubtiList:BG12742" /db_xref="UniProtKB/Swiss-Prot:O31454" /translation="MEKQIISWITDYQNTGDEAVLRQVREVCWPIVEAVLQEKVMDDE QANNLREKGIERFPFIISKYQADVQLPVETFLQNTYRFYFHQVMRESS*" gene 249595..249873 /gene="ybfN" /locus_tag="BSU_02300" /old_locus_tag="BSU02300" promotor_-35 249916..249925 /Source="Nicolas_upshift_promotors" /id="U161" /multdbtbs="SigW" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1688 /SigmaFactorBS="agcttctttcaacagagaagcttttttttgttggcaggaaaa GGAAACTTTTtctatatctatcTCGTAATGACTAGAGAacctagcagaaaaggagaga t" /listShort="ybfO, ybfP, S89, ybfQ" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 249934 /Source="Nicolas_upshifts" /id="U161" /multdbtbs="SigW" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1688 /SigmaFactorBS="agcttctttcaacagagaagcttttttttgttggcaggaaaa GGAAACTTTTtctatatctatcTCGTAATGACTAGAGAacctagcagaaaaggagaga t" /listShort="ybfO, ybfP, S89, ybfQ" /GFF_Attribute="listLong" promotor_-10 249938..249953 /Source="Nicolas_upshift_promotors" /id="U161" /multdbtbs="SigW" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1688 /SigmaFactorBS="agcttctttcaacagagaagcttttttttgttggcaggaaaa GGAAACTTTTtctatatctatcTCGTAATGACTAGAGAacctagcagaaaaggagaga t" /listShort="ybfO, ybfP, S89, ybfQ" /GFF_Attribute="listLong" /label="promotor_-10" CDS 249979..251319 /gene="ybfO" /locus_tag="BSU_02310" /old_locus_tag="BSU02310" /EC_number="3.-.-.-" /function="16.8: Protect" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative exported hydrolase" /protein_id="NP_388113.1" /db_xref="EnsemblGenomes-Gn:BSU02310" /db_xref="EnsemblGenomes-Tr:CAB12025" /db_xref="GOA:O31455" /db_xref="InterPro:IPR007815" /db_xref="SubtiList:BG12743" /db_xref="UniProtKB/Swiss-Prot:O31455" /translation="MKRMIVRMTLPLLIVCLAFSSFSASARAASEEKYWDHWIERHAQ PLDASNASNKDLRFLKKVLKGKRIVQLGETTHGAGEINATKVRMIKYLHEELGYDVLA FESGFPDTNASYLNMDQLTPKSTMKNSIYAVWHTEDVVELFDYMKEQKEKGDPLILTG FDIQSMKNSFNVAATQWVKAVDPEKAELLSQSENDFSTLVTDSNTFDEFSQKKEKLVK NYQKLIKFTKTHASELKENLPKEPKAYEMFMHSLQLRIDVMETYMLEEMKEKLEEYPE NIEDFSFFMRDRMMAEQFQWVADTLYPKKKIIVWGHNYHLRKQNTKMIKDWVQLNGPN MGDYLPERLKKQTYTIGIYAYSGASLDSSDNKTVKPVTSPPPSGSLEALLKAADRPAV FVDFLHTKNKKGTSWMYTPRTALYWGYMEEQMILKEQYDGVIWLEHITPSVIIK*" gene 249979..251319 /gene="ybfO" /locus_tag="BSU_02310" /old_locus_tag="BSU02310" downshifts 251319 /Source="Nicolas_upshifts" /id="D87" /incds=0 /nref=12 /ntot=60 /MaxReadThrough="3.64301" /MaxDrop="6.34998" /score="14.4442651" /energy="-13.3" /TU="U161" /idTUdmin="U162" /TUdmin="-1122" /isTUend="FALSE" upshifts 251385 /Source="Nicolas_upshifts" /id="U162" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.582417582417582" /psig="0.838161838161838" /xcortree=1579 /SigmaFactorBS="gtcccctgtggtaaacaggggatttttacatatcgcaaaaat aatcaaaacatataatccgtgATCCATTATTCTAAAACAGAaaggagattggagcgtg c" /listShort="ybfP, S89" /listLong="ybfQ" misc_feature 251388..251407 /Source="Nicolas_upshift_promotors" /id="U162" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.582417582417582" /psig="0.838161838161838" /xcortree=1579 /SigmaFactorBS="gtcccctgtggtaaacaggggatttttacatatcgcaaaaat aatcaaaacatataatccgtgATCCATTATTCTAAAACAGAaaggagattggagcgtg c" /listShort="ybfP, S89" /listLong="ybfQ" /label="promotor_single_box" /note="Geneious type: promotor_single_box" CDS 251427..252314 /gene="ybfP" /locus_tag="BSU_02320" /old_locus_tag="BSU02320" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative transcriptional regulator (AraC/XylS family)" /protein_id="NP_388114.1" /db_xref="EnsemblGenomes-Gn:BSU02320" /db_xref="EnsemblGenomes-Tr:CAB12026" /db_xref="GOA:O31456" /db_xref="InterPro:IPR008979" /db_xref="InterPro:IPR009057" /db_xref="InterPro:IPR018060" /db_xref="SubtiList:BG12744" /db_xref="UniProtKB/Swiss-Prot:O31456" /translation="MYYEKAVQKTINWIESHLHEQISNEDIVNVSSFSKFHFHRIFQK EVGMSVASYIRLRRLANAAAALLYTDHRIIDIALYYQFESQEAFTRTFKKMYHMPPGA YRTFMKRFTSKKEESYMEKKMKGWVLSGSHPFQFEMGIDRENVHQGKASGYLKSTMVQ DIGEFATMMQQFKADRYLGKRLRLSSFIKTKGVQHFASLWMRVDSAADDVLQFDNMSN RPITGTTNWNHYAIVLDVPENSAVISFGVQLSGPGQVWMDHVVFEEVDESVPSTNLEM PGELLDEPVNLSFEEELQK*" gene 251427..252314 /gene="ybfP" /locus_tag="BSU_02320" /old_locus_tag="BSU02320" S_feature 252315..252458 /Source="Nicolas_S_feature" /locus_tag="new_252315_252458" /HighExp="T0.30H, T-1.40H, T0.0H, T-1.10H, Salt, aero, ferm, T-0.40H, T-2.40H, B60" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigWXY" /TUshortPSig="0.838, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S89" promotor_-35 252430..252437 /Source="Nicolas_upshift_promotors" /id="U163" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.754245754245754" /psig=1 /xcortree=2069 /SigmaFactorBS="gcttggatatttttatcagtctgggcggatCTGTTCATcttt gcggcatttTCCTGTATGATATAGTAAGAgtgtgcatagcaactaactataattgaac a" /listShort="ybfQ" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 252451..252470 /Source="Nicolas_upshift_promotors" /id="U163" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.754245754245754" /psig=1 /xcortree=2069 /SigmaFactorBS="gcttggatatttttatcagtctgggcggatCTGTTCATcttt gcggcatttTCCTGTATGATATAGTAAGAgtgtgcatagcaactaactataattgaac a" /listShort="ybfQ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 252460 /Source="Nicolas_upshifts" /id="U163" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.754245754245754" /psig=1 /xcortree=2069 /SigmaFactorBS="gcttggatatttttatcagtctgggcggatCTGTTCATcttt gcggcatttTCCTGTATGATATAGTAAGAgtgtgcatagcaactaactataattgaac a" /listShort="ybfQ" /GFF_Attribute="listLong" CDS 252514..253482 /gene="ybfQ" /locus_tag="BSU_02330" /old_locus_tag="BSU02330" /function="16.11: Scavenge (Catabolism)" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 10939241, 22720735; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative enzyme with rhodanese domain" /protein_id="NP_388115.1" /db_xref="EnsemblGenomes-Gn:BSU02330" /db_xref="EnsemblGenomes-Tr:CAB12027" /db_xref="InterPro:IPR001763" /db_xref="InterPro:IPR020936" /db_xref="InterPro:IPR022111" /db_xref="InterPro:IPR036873" /db_xref="SubtiList:BG12745" /db_xref="UniProtKB/Swiss-Prot:O31457" /translation="MEKQYRVLLYYKYVPIEDPEAFREQHLAFCKELGLLGRILVSSE GINGTVSGTVEQTEKYMETMKADPRFADMVFKIDEAEGHAFKKIFVRHKKELVTLRLE DDVDPNETTGQHLKPAEFYEKMQDPNTIVIDARNDYEYDLGHFRGAVRPDIEAFRELP EWIEEHKDMLEGKKILTYCTGGVRCEKFSGWLVKQGFEDVAQLDGGIVTYGKDPEVQG KLWDGQCYVFDERISVPVNRVEHVIVGKDYFTGEPCERYVNCANPSCNKKMICTPENE YKYMRSCSHECRTNPRNLYVKEHNMTEEEVNARLAAIETEDHAAAE*" gene 252514..253482 /gene="ybfQ" /locus_tag="BSU_02330" /old_locus_tag="BSU02330" promotor_-10 complement(253336..253354) /Source="Nicolas_upshift_promotors" /id="U164" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.987012987012987" /psig="0.987012987012987" /xcortree=798 /SigmaFactorBS="attatgctctttcacatacaggtttcttgggttcgtgcGGCA TTcgtggctgcagctgcGCATATATTTATACTCATTttccggtgtgcatatcattttt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(253353) /Source="Nicolas_upshifts" /id="U164" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.987012987012987" /psig="0.987012987012987" /xcortree=798 /SigmaFactorBS="attatgctctttcacatacaggtttcttgggttcgtgcGGCA TTcgtggctgcagctgcGCATATATTTATACTCATTttccggtgtgcatatcattttt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(253370..253375) /Source="Nicolas_upshift_promotors" /id="U164" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.987012987012987" /psig="0.987012987012987" /xcortree=798 /SigmaFactorBS="attatgctctttcacatacaggtttcttgggttcgtgcGGCA TTcgtggctgcagctgcGCATATATTTATACTCATTttccggtgtgcatatcattttt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 253479 /Source="Nicolas_upshifts" /id="D88" /incds=0 /nref=238 /ntot=271 /MaxReadThrough="2.06825" /MaxDrop="7.49655" /score="4.11635522" /energy="-7.8" /TU="U163" /idTUdmin="U161" /TUdmin=4 /isTUend="TRUE" downshifts complement(253518) /Source="Nicolas_upshifts" /id="D89" /incds=0 /nref=59 /ntot=147 /MaxReadThrough="0.54212" /MaxDrop="6.33244" /score="2.56774646" /energy="-7.5" /TU="NA" /idTUdmin="U165" /TUdmin=11 /isTUend="TRUE" CDS complement(253518..254762) /gene="gltP" /locus_tag="BSU_02340" /old_locus_tag="BSU02340" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:7751298, 15849754, 16850406" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7751298, 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="proton/glutamate symport protein" /protein_id="NP_388116.1" /db_xref="EnsemblGenomes-Gn:BSU02340" /db_xref="EnsemblGenomes-Tr:CAB12028" /db_xref="GOA:P39817" /db_xref="InterPro:IPR001991" /db_xref="InterPro:IPR018107" /db_xref="InterPro:IPR033380" /db_xref="InterPro:IPR036458" /db_xref="SubtiList:BG11015" /db_xref="UniProtKB/Swiss-Prot:P39817" /translation="MKKLIAFQILIALAVGAVIGHFFPDFGMALRPVGDGFIRLIKMI VVPIVFSTIVIGAAGSGSMKKMGSLGIKTIIWFEVITTLVLGLGLLLANVLKPGVGLD LSHLAKKDIHELSGYTDKVVDFKQMILDIIPTNIIDVMARNDLLAVIFFAILFGVAAA GIGKASEPVMKFFESTAQIMFKLTQIVMVTAPIGVLALMAASVGQYGIELLLPMFKLV GTVFLGLFLILFVLFPLVGLIFQIKYFEVLKMIWDLFLIAFSTTSTETILPQLMDRME KYGCPKRVVSFVVPSGLSLNCDGSSLYLSVSCIFLAQAFQVDMTLSQQLLMMLVLVMT SKGIAAVPSGSLVVLLATANAVGLPAEGVAIIAGVDRVMDMARTGVNVPGHAIACIVV SKWEKAFRQKEWVSANSQTESI*" gene complement(253518..254762) /gene="gltP" /locus_tag="BSU_02340" /old_locus_tag="BSU02340" promotor_-10 complement(254796..254814) /Source="Nicolas_upshift_promotors" /id="U165" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.996003996003996" /psig="0.996003996003996" /xcortree=525 /SigmaFactorBS="tgaaagcgctgtcaaaataaaataacttgaaaAAAGGTGTTt gcatttgaaTCACGAATGATATGAATATgcctacattctatcgttctaaagggggatt c" /listShort="gltP" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(254805) /Source="Nicolas_upshifts" /id="U165" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.996003996003996" /psig="0.996003996003996" /xcortree=525 /SigmaFactorBS="tgaaagcgctgtcaaaataaaataacttgaaaAAAGGTGTTt gcatttgaaTCACGAATGATATGAATATgcctacattctatcgttctaaagggggatt c" /listShort="gltP" /GFF_Attribute="listLong" promotor_-35 complement(254825..254833) /Source="Nicolas_upshift_promotors" /id="U165" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.996003996003996" /psig="0.996003996003996" /xcortree=525 /SigmaFactorBS="tgaaagcgctgtcaaaataaaataacttgaaaAAAGGTGTTt gcatttgaaTCACGAATGATATGAATATgcctacattctatcgttctaaagggggatt c" /listShort="gltP" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(254833..254851) /Source="Nicolas_upshift_promotors" /id="U166" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.949050949050949" /psig="0.949050949050949" /xcortree=797 /SigmaFactorBS="taaaaaagtcccccctgctgcgggggactttttcgccAACAT AatgaaagcgctgtcaAAATAAAATAACTTGAAAAaaggtgtttgcatttgaatcacg a" /listShort="gltP" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(254849) /Source="Nicolas_upshifts" /id="U166" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.949050949050949" /psig="0.949050949050949" /xcortree=797 /SigmaFactorBS="taaaaaagtcccccctgctgcgggggactttttcgccAACAT AatgaaagcgctgtcaAAATAAAATAACTTGAAAAaaggtgtttgcatttgaatcacg a" /listShort="gltP" /GFF_Attribute="listLong" promotor_-35 complement(254867..254872) /Source="Nicolas_upshift_promotors" /id="U166" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.949050949050949" /psig="0.949050949050949" /xcortree=797 /SigmaFactorBS="taaaaaagtcccccctgctgcgggggactttttcgccAACAT AatgaaagcgctgtcaAAATAAAATAACTTGAAAAaaggtgtttgcatttgaatcacg a" /listShort="gltP" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(254907..256802) /gene="gamP" /locus_tag="BSU_02350" /old_locus_tag="BSU02350" /EC_number="2.7.1.193" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 10627040, 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="phosphotransferase system (PTS) glucosamine-specific enzyme IICBA component" /protein_id="NP_388117.1" /db_xref="EnsemblGenomes-Gn:BSU02350" /db_xref="EnsemblGenomes-Tr:CAB12029" /db_xref="GOA:P39816" /db_xref="InterPro:IPR001127" /db_xref="InterPro:IPR001996" /db_xref="InterPro:IPR003352" /db_xref="InterPro:IPR011055" /db_xref="InterPro:IPR011299" /db_xref="InterPro:IPR013013" /db_xref="InterPro:IPR018113" /db_xref="InterPro:IPR036878" /db_xref="SubtiList:BG11014" /db_xref="UniProtKB/Swiss-Prot:P39816" /translation="MFKKAFQILQQLGRALMTPVAVLPAAGLLLRFGDKDLLNIPIIK DAGGVVFDNLPLIFAVGVAIGLAGGEGVAGLAAVIGYLILTVTLDNMGKLLGLQPPYE GAEHLIDMGVFGGIIIGLLAAYLYKRFSSIELHPVLGFFSGKRFVPIITSVSSLVIGV IFSFVWPLIQNGINAASSLIADSTVGLFFYATIYRLLIPFGLHHIFYTPFYFMMGEYT DPSTGNTVTGDLTRFFAGDPTAGRFMMGDFPYMIFCLPAVALAIIHTARPEKKKMISG VMISAALTSMLTGITEPVEFSFLFVAPVLYLINSILAGVIFVVCDLFHVRHGYTFSGG GIDYVLNYGLSTNGWVVIPVGIVFAFIYYYLFRFAILKWNLKTPGRETDEDGQNEEKA PVAKDQLAFHVLQALGGQQNIANLDACITRLRVTVHQPSQVCKDELKRLGAVGVLEVN NNFQAIFGTKSDALKDDIKTIMAGGVPATAAALDTVTDKPLKPDSDETFIYPIKGETV SLGDVPDQVFSEKMMGEGFAIIPSEGKVVAPADGEIVSIFPTKHAIGFMSAGGTEILI HVGIDTVKLNGEGFEAHVTSGQAVKQGELLLTFDLNYIKQHAASAITPVIFTNTSEED LKHIQMK*" gene complement(254907..256802) /gene="gamP" /locus_tag="BSU_02350" /old_locus_tag="BSU02350" downshifts complement(254923) /Source="Nicolas_upshifts" /id="D90" /incds=0 /nref=56 /ntot=192 /MaxReadThrough="1.9947" /MaxDrop="6.51864" /score="5.87664177" /energy="-12.1" /TU="NA" /idTUdmin="U168" /TUdmin="-8" /isTUend="TRUE" misc_feature 256668..256687 /Source="Nicolas_upshift_promotors" /id="U167" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.701298701298701" /psig="0.975024975024975" /xcortree=2747 /SigmaFactorBS="cggcgaaaatcagcggaaggttatcgaatacaacgccgcccg cATCCTTTATAATAGGGATGTtcagtaaatccttgtctccgaaacggagcaaaagacc t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 256685 /Source="Nicolas_upshifts" /id="U167" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.701298701298701" /psig="0.975024975024975" /xcortree=2747 /SigmaFactorBS="cggcgaaaatcagcggaaggttatcgaatacaacgccgcccg cATCCTTTATAATAGGGATGTtcagtaaatccttgtctccgaaacggagcaaaagacc t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" CDS complement(256823..257572) /gene="gamA" /locus_tag="BSU_02360" /old_locus_tag="BSU02360" /EC_number="3.5.99.6" /function="16.11: Scavenge (Catabolism)" /function="16.13: Shape" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:23667565, 27002132" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 23667565, 27002132; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="glucosamine-6-phosphate deaminase" /protein_id="NP_388118.1" /db_xref="EnsemblGenomes-Gn:BSU02360" /db_xref="EnsemblGenomes-Tr:CAB12030" /db_xref="GOA:O31458" /db_xref="InterPro:IPR004547" /db_xref="InterPro:IPR006148" /db_xref="InterPro:IPR018321" /db_xref="SubtiList:BG12746" /db_xref="UniProtKB/Swiss-Prot:O31458" /translation="MKILIAEHYEELCKLSAAIIKEQIQAKKDAVLGLATGSTPVGLY KQLISDYQAGEIDFSKVTTFNLDEYAGLSPSHPQSYNHFMHEHLFQHINMQPDHIHIP QGDNPQLEAACKVYEDLIRQAGGIDVQILGIGANGHIGFNEPGSDFEDRTRVVKLSES TIQANARFFGGDPVLVPRLAISMGIKTIMEFSKHIVLLASGEEKADAIQKMAEGPVTT DVPASILQKHNHVTVIADYKAAQKLKSASFS*" gene complement(256823..257572) /gene="gamA" /locus_tag="BSU_02360" /old_locus_tag="BSU02360" S_feature 257545..257726 /Source="Nicolas_S_feature" /locus_tag="new_257545_257726" /HighExp="H2O2, T1.30H, G135, dia15, G150, G180, LBGstat, T2.0H, T0.30H, M9-stat" /AntisenseName="nagBB" /AntisenseCor="0.458837556034909" /AntisenseRegPval="-14.7" /CDS_PredictionProba="NA" /TUshortSig="NA" /TUshortPSig="NA" /TUlongSig="NA" /TUlongPSig="NA" /label="S90" S_feature complement(257573..257643) /Source="Nicolas_S_feature" /locus_tag="new_257573_257643_c" /HighExp="S1, Diami, MG 5, MG t5, dia5, MG 15, MG 10, LPhT, Paraq, G150" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S91" promotor_-10 complement(257632..257651) /Source="Nicolas_upshift_promotors" /id="U168" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.98901098901099" /psig=1 /xcortree=2202 /SigmaFactorBS="atccttcttttataacaaattttcagaaattaaTATTGACAg tttgataagggcggTGCTAAATTCGTAATGACAAgtatcataaattggtcataacaaa t" /listShort="S91, nagBB, nagP" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(257647) /Source="Nicolas_upshifts" /id="U168" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.98901098901099" /psig=1 /xcortree=2202 /SigmaFactorBS="atccttcttttataacaaattttcagaaattaaTATTGACAg tttgataagggcggTGCTAAATTCGTAATGACAAgtatcataaattggtcataacaaa t" /listShort="S91, nagBB, nagP" /GFF_Attribute="listLong" promotor_-35 complement(257667..257674) /Source="Nicolas_upshift_promotors" /id="U168" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.98901098901099" /psig=1 /xcortree=2202 /SigmaFactorBS="atccttcttttataacaaattttcagaaattaaTATTGACAg tttgataagggcggTGCTAAATTCGTAATGACAAgtatcataaattggtcataacaaa t" /listShort="S91, nagBB, nagP" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 257713..257720 /Source="Nicolas_upshift_promotors" /id="U169" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.662337662337662" /psig=1 /xcortree=1865 /SigmaFactorBS="gtcaatattaatttctgaaaatttgttataaaagaaggatac aaaTCTTTCATattgggagggcaAATGGTATTATGGTCTCAATgaaaaagaacggatt g" /listShort="ybgA, ybgB" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 257728 /Source="Nicolas_upshifts" /id="U169" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.662337662337662" /psig=1 /xcortree=1865 /SigmaFactorBS="gtcaatattaatttctgaaaatttgttataaaagaaggatac aaaTCTTTCATattgggagggcaAATGGTATTATGGTCTCAATgaaaaagaacggatt g" /listShort="ybgA, ybgB" /GFF_Attribute="listLong" promotor_-10 257733..257752 /Source="Nicolas_upshift_promotors" /id="U169" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.662337662337662" /psig=1 /xcortree=1865 /SigmaFactorBS="gtcaatattaatttctgaaaatttgttataaaagaaggatac aaaTCTTTCATattgggagggcaAATGGTATTATGGTCTCAATgaaaaagaacggatt g" /listShort="ybgA, ybgB" /GFF_Attribute="listLong" /label="promotor_-10" CDS 257791..258498 /gene="gamR" /locus_tag="BSU_02370" /old_locus_tag="BSU02370" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:23667565, 24673833" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 23667565, 24673833; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator-GlcN6P (GntR family)" /protein_id="NP_388119.1" /db_xref="EnsemblGenomes-Gn:BSU02370" /db_xref="EnsemblGenomes-Tr:CAB12031" /db_xref="GOA:O31459" /db_xref="InterPro:IPR000524" /db_xref="InterPro:IPR011663" /db_xref="InterPro:IPR028978" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG12747" /db_xref="UniProtKB/Swiss-Prot:O31459" /translation="MTALYSVIKFKIIELIKSGKYQANDQLPTESEFCEQYDVSRTTV RLALQQLELEGYIKRIQGKGTFVSAAKIQTPIPHKITSFAEQMRGLRSESKVLELVVI PADHSIAELLKMKENEPVNKLVRVRYAEGEPLQYHTSYIPWKAAPGLAQEECTGSLFE LLRTKYNIEISRGTESIEPILTDETISGHLLTNVGAPAFLSESLTYDKNEEVVEYAQI ITRGDRTKFTVEQSYHS*" gene 257791..258498 /gene="gamR" /locus_tag="BSU_02370" /old_locus_tag="BSU02370" promotor_-35 258464..258465 /Source="Nicolas_upshift_promotors" /id="U170" /multdbtbs="SigY" /comp="M9" /sig="Sig-" /pcomp="0.41958041958042" /psig="0.41958041958042" /xcortree=1684 /SigmaFactorBS="aatatgcgcaaattattacacggggagaccgaaCGaaattca ccgtagaaCAGTCATATCATTCAtaaagcaatgtgttttaagaagggaatggtggttc t" /listShort="ybgB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 258481..258495 /Source="Nicolas_upshift_promotors" /id="U170" /multdbtbs="SigY" /comp="M9" /sig="Sig-" /pcomp="0.41958041958042" /psig="0.41958041958042" /xcortree=1684 /SigmaFactorBS="aatatgcgcaaattattacacggggagaccgaaCGaaattca ccgtagaaCAGTCATATCATTCAtaaagcaatgtgttttaagaagggaatggtggttc t" /listShort="ybgB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 258491 /Source="Nicolas_upshifts" /id="U170" /multdbtbs="SigY" /comp="M9" /sig="Sig-" /pcomp="0.41958041958042" /psig="0.41958041958042" /xcortree=1684 /SigmaFactorBS="aatatgcgcaaattattacacggggagaccgaaCGaaattca ccgtagaaCAGTCATATCATTCAtaaagcaatgtgttttaagaagggaatggtggttc t" /listShort="ybgB" /GFF_Attribute="listLong" CDS 258532..258807 /gene="ybgB" /locus_tag="BSU_02380" /old_locus_tag="BSU02380" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 12897008, 23667565" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function (B. subtilis-specific)" /protein_id="NP_388120.1" /db_xref="EnsemblGenomes-Gn:BSU02380" /db_xref="EnsemblGenomes-Tr:CAB12032" /db_xref="GOA:O31460" /db_xref="InterPro:IPR012867" /db_xref="SubtiList:BG12748" /db_xref="UniProtKB/Swiss-Prot:O31460" /translation="MFLFTNGKVLWGAVIAAFILSIVFYPFLPTQMPIHYDVANSPDL TVNKLAGTVMLPVLMVVFAWARKINWQFVFAVYILLICHIVVLCLAL*" gene 258532..258807 /gene="ybgB" /locus_tag="BSU_02380" /old_locus_tag="BSU02380" promotor_-10 complement(258590..258608) /Source="Nicolas_upshift_promotors" /id="U171" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.977022977022977" /psig="0.977022977022977" /xcortree=112 /SigmaFactorBS="ggactgttcgcaacatcataatgaatcGGCATCTgcgtcggc agaaaaGGGTAAAATACAATTGAAAggatgaatgcagcaatcactgctccccacagca c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(258596) /Source="Nicolas_upshifts" /id="U171" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.977022977022977" /psig="0.977022977022977" /xcortree=112 /SigmaFactorBS="ggactgttcgcaacatcataatgaatcGGCATCTgcgtcggc agaaaaGGGTAAAATACAATTGAAAggatgaatgcagcaatcactgctccccacagca c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(258623..258629) /Source="Nicolas_upshift_promotors" /id="U171" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.977022977022977" /psig="0.977022977022977" /xcortree=112 /SigmaFactorBS="ggactgttcgcaacatcataatgaatcGGCATCTgcgtcggc agaaaaGGGTAAAATACAATTGAAAggatgaatgcagcaatcactgctccccacagca c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 258799 /Source="Nicolas_upshifts" /id="D91" /incds=0 /nref=20 /ntot=130 /MaxReadThrough="2.42422" /MaxDrop="3.75723" /score="4.58454735" /energy="-9.4" /TU="NA" /idTUdmin="U169" /TUdmin=0 /isTUend="TRUE" promotor_-35 258850..258854 /Source="Nicolas_upshift_promotors" /id="U172" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.641358641358641" /psig="0.998001998001998" /xcortree=2879 /SigmaFactorBS="gccagaataaaactggctgttttctttaatttcaGCTTCatc tgacaatgaatgTGGTGTATAATAGCTGATGAtcctaaagaatattctgaaatttata g" /listShort="S92, ilvE" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 258870..258889 /Source="Nicolas_upshift_promotors" /id="U172" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.641358641358641" /psig="0.998001998001998" /xcortree=2879 /SigmaFactorBS="gccagaataaaactggctgttttctttaatttcaGCTTCatc tgacaatgaatgTGGTGTATAATAGCTGATGAtcctaaagaatattctgaaatttata g" /listShort="S92, ilvE" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 258876 /Source="Nicolas_upshifts" /id="U172" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.641358641358641" /psig="0.998001998001998" /xcortree=2879 /SigmaFactorBS="gccagaataaaactggctgttttctttaatttcaGCTTCatc tgacaatgaatgTGGTGTATAATAGCTGATGAtcctaaagaatattctgaaatttata g" /listShort="S92, ilvE" /GFF_Attribute="listLong" S_feature 258887..259015 /Source="Nicolas_S_feature" /locus_tag="new_258887_259015" /HighExp="T2.30H, S5, T2.0H, T1.30H, M9-stat, T3.0H, T3.30H, S4, T1.0H, T-0.40H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.998" /TUlongSig="NA" /TUlongPSig="NA" /label="S92" CDS 259016..260086 /gene="ilvE" /locus_tag="BSU_02390" /old_locus_tag="BSU02390" /EC_number="2.6.1.42" /function="16.11: Scavenge (Catabolism)" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:12670965, 15060025, 15102328, 20332210, 23429746" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12670965, 15060025, 15102328, 20332210, 23429746; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="isoleucine-valine aminotransferase / aromatic amino acid aminotransferase" /protein_id="NP_388121.1" /db_xref="EnsemblGenomes-Gn:BSU02390" /db_xref="EnsemblGenomes-Tr:CAB12033" /db_xref="GOA:O31461" /db_xref="InterPro:IPR001544" /db_xref="InterPro:IPR005786" /db_xref="InterPro:IPR018300" /db_xref="InterPro:IPR033939" /db_xref="InterPro:IPR036038" /db_xref="SubtiList:BG12749" /db_xref="UniProtKB/Swiss-Prot:O31461" /translation="MNKLIEREKTVYYKEKPDPSSLGFGQYFTDYMFVMDYEEGIGWH HPRIAPYAPLTLDPSSSVFHYGQAVFEGLKAYRTDDGRVLLFRPDQNIKRLNRSCERM SMPPLDEELVLEALTQLVELEKDWVPKEKGTSLYIRPFVIATEPSLGVKASRSYTFMI VLSPVGSYYGDDQLKPVRIYVEDEYVRAVNGGVGFAKTAGNYAASLQAQRKANELGYD QVLWLDAIEKKYVEEVGSMNIFFVINGEAVTPALSGSILSGVTRASAIELIRSWGIPV REERISIDEVYAASARGELTEVFGTGTAAVVTPVGELNIHGKTVIVGDGQIGDLSKKL YETITDIQLGKVKGPFNWTVEV*" gene 259016..260086 /gene="ilvE" /locus_tag="BSU_02390" /old_locus_tag="BSU02390" downshifts 260075 /Source="Nicolas_upshifts" /id="D92" /incds=0 /nref=124 /ntot=245 /MaxReadThrough="1.34575" /MaxDrop="6.88046" /score="13.1364544" /energy="-9.4" /TU="NA" /idTUdmin="U172" /TUdmin=0 /isTUend="TRUE" CDS complement(260123..261535) /gene="ybgF" /locus_tag="BSU_02400" /old_locus_tag="BSU02400" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 7704263, 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative aminoacid permease" /protein_id="NP_388122.1" /db_xref="EnsemblGenomes-Gn:BSU02400" /db_xref="EnsemblGenomes-Tr:CAB12034" /db_xref="GOA:O31462" /db_xref="InterPro:IPR002293" /db_xref="InterPro:IPR004840" /db_xref="InterPro:IPR004841" /db_xref="SubtiList:BG12750" /db_xref="UniProtKB/Swiss-Prot:O31462" /translation="MNSAHNKNETTFQRSMKSRHLFMLSLGGVIGTGLFLSSGYTIQQ AGPAGTILAYLVGAGIVYLVMLCLGELSVAMPVTGAFHTYAAKYIGPGTGFTVAWLYW LTWTVALGSEFTAAGLLMQRWFPHTSVWMWSAVFALFIFLLNAFSVKFFAESEFWFSS IKVLAIVLFILLGGSAMFGIIPIKGGEAAPMLSNFTAEGGLFPNGFVPILMTMLSVNF AFSGTELIGIAAGESVDPDKTIPKAIKTTVWRLSLFFVGTIFVLSGLIPIQDAGVIKS PFVAVFDRVGVPYAADIMNFVILTAILSAANSGLYASSRMLWSLSKEKTLHPTFAKLT SKGTPFNALVFSMIGGILSLLSSVFAPDTVYVVLVSISGFAVVVVWMGIAASQFMFRK RYIEAGNKVTDLKYRTPLYPFVPIAAFLLCLASVVGIAFDPNQRIALYCGVPFMAICY AIYYVKNRKSQPAADMTHSK*" gene complement(260123..261535) /gene="ybgF" /locus_tag="BSU_02400" /old_locus_tag="BSU02400" downshifts complement(260140) /Source="Nicolas_upshifts" /id="D93" /incds=0 /nref=43 /ntot=166 /MaxReadThrough="0.37503" /MaxDrop="5.92001" /score="6.94246417" /energy="-9.4" /TU="NA" /idTUdmin="U173" /TUdmin="-11" /isTUend="TRUE" S_feature complement(261536..261647) /Source="Nicolas_S_feature" /locus_tag="new_261536_261647_c" /HighExp="BMM, S1, MG 45, MG 60, UNK1, MG t5, MG 10, MG 90, MG-0.2, M9-exp" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="SigA" /TUlongPSig="0.999" /label="S93" promotor_-10 complement(261620..261639) /Source="Nicolas_upshift_promotors" /id="U173" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.943056943056943" /psig=1 /xcortree=3071 /SigmaFactorBS="cgaaaatattcaagaaattgcggcttgggcccgctctttaaa aacaACTTGACTtatcggaatagtttGTATATTCTAACTTAAAGCCggttcgccggag t" /listShort="S93, ybgF" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(261647) /Source="Nicolas_upshifts" /id="U173" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.943056943056943" /psig=1 /xcortree=3071 /SigmaFactorBS="cgaaaatattcaagaaattgcggcttgggcccgctctttaaa aacaACTTGACTtatcggaatagtttGTATATTCTAACTTAAAGCCggttcgccggag t" /listShort="S93, ybgF" /GFF_Attribute="listLong" promotor_-35 complement(261654..261661) /Source="Nicolas_upshift_promotors" /id="U173" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.943056943056943" /psig=1 /xcortree=3071 /SigmaFactorBS="cgaaaatattcaagaaattgcggcttgggcccgctctttaaa aacaACTTGACTtatcggaatagtttGTATATTCTAACTTAAAGCCggttcgccggag t" /listShort="S93, ybgF" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(261656..262603) /gene="ybgG" /locus_tag="BSU_02410" /old_locus_tag="BSU02410" /EC_number="2.1.1.10" /function="16.6: Maintain" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 11267663, 15995196, 17264075; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="homocysteine methylase using (R,S)AdoMet" /protein_id="NP_388123.1" /db_xref="EnsemblGenomes-Gn:BSU02410" /db_xref="EnsemblGenomes-Tr:CAB12035" /db_xref="GOA:O31463" /db_xref="InterPro:IPR003726" /db_xref="InterPro:IPR017226" /db_xref="InterPro:IPR036589" /db_xref="SubtiList:BG12751" /db_xref="UniProtKB/Swiss-Prot:O31463" /translation="MNPIQHILDTYPLIVLDGAMATELERKGCNLNDSLWSAKILMEE PELIKQVHTDYFAAGADCAITASYQSTFEGFAARGLSEAEARRLIELSVSIAAEARDE FWSLEENRLNRPKPIIAASIGPYGAYLADGSEYRGNYAISEDELIEFHRPRMKALIEA GADVLACETIPCLTEAKAIVRLLKEFPETYAWISFSAKDGLHISDGTPAADCASWLDE HRQIAALGINCTPLQHIPSLIEELKKNTSKPIIVYPNSGEQYDPETKTWNGAACAESY GASARTWHEKGARLIGGCCRTKPENIQEIAAWARSLKTT*" gene complement(261656..262603) /gene="ybgG" /locus_tag="BSU_02410" /old_locus_tag="BSU02410" promotor_-10 complement(262641..262660) /Source="Nicolas_upshift_promotors" /id="U174" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.993006993006993" /psig="0.999000999001" /xcortree=3068 /SigmaFactorBS="agacatatgggctgaacacctttctctttttgcgttTATTGA CAaacacgtaagcctcCATTACGATTTTCATATCTTtttcaaaaaaatctgaaagaag g" /listShort="ybgG" /listLong="S93, ybgF" /label="promotor_-10" upshifts complement(262658) /Source="Nicolas_upshifts" /id="U174" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.993006993006993" /psig="0.999000999001" /xcortree=3068 /SigmaFactorBS="agacatatgggctgaacacctttctctttttgcgttTATTGA CAaacacgtaagcctcCATTACGATTTTCATATCTTtttcaaaaaaatctgaaagaag g" /listShort="ybgG" /listLong="S93, ybgF" promotor_-35 complement(262675..262682) /Source="Nicolas_upshift_promotors" /id="U174" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.993006993006993" /psig="0.999000999001" /xcortree=3068 /SigmaFactorBS="agacatatgggctgaacacctttctctttttgcgttTATTGA CAaacacgtaagcctcCATTACGATTTTCATATCTTtttcaaaaaaatctgaaagaag g" /listShort="ybgG" /listLong="S93, ybgF" /label="promotor_-35" CDS complement(262732..264168) /gene="glnT" /locus_tag="BSU_02420" /old_locus_tag="BSU02420" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2b: Function from indirect experimental evidences (e.g. phenotypes); PubMedId: 15849754, 15995196, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="glutamine transporter" /protein_id="NP_388124.2" /db_xref="EnsemblGenomes-Gn:BSU02420" /db_xref="EnsemblGenomes-Tr:CAB12036" /db_xref="GOA:O31464" /db_xref="InterPro:IPR001463" /db_xref="SubtiList:BG12752" /db_xref="UniProtKB/Swiss-Prot:O31464" /translation="MQQILEHIVGIANDLLWSKLLIVLLLSFGIYFTFRLKFLQVRML KEMVRVLREGAASRSKNSISPFQAFCISMAARVGTGNITGIAIAIALGGPGAIFWMWI IAIIGSASSFVESTLAQIYKVKDVNGFRGGPAYYMEKGLNKRWMGALFAVLITLSFGI VFNSVQSNTVSLAFENAFGTNRLTLGLILIAVFGTIIFGGVKRIAKLAESIVVVLAVL YIGVAFFVIFSNITQLPGVLALIVKNAFGFDQAAGGALGAALMQGVRRGIFSNEAGMG SAPNAAATATTSHPVKQGLIQAFGVLTDTLVICTSTAFIILFSDAYHTPGLSGIALTQ ASLSSHVGSWASGFLAILILLFGFCALIGNYYYGETNIGFLNKSKKLIFVYRIGVLAM IVFGCVAKVQLVWDLADLFMGLMVIVNLIAIFLLSKVVFTALKDYTRQKKAGKDPVFY KDVLKNHNGIECWPVSDTKTDTHNKQIS*" gene complement(262732..264168) /gene="glnT" /locus_tag="BSU_02420" /old_locus_tag="BSU02420" downshifts complement(262747) /Source="Nicolas_upshifts" /id="D94" /incds=0 /nref=3 /ntot=3 /MaxReadThrough="0.598370000000001" /MaxDrop="4.3935" /score="-7.90227391" /energy="-11.4" /TU="NA" /idTUdmin="U174" /TUdmin="-1078" /isTUend="FALSE" CDS complement(264191..265174) /gene="glsA" /locus_tag="BSU_02430" /old_locus_tag="BSU02430" /EC_number="3.5.1.2" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:15995196, 18459799, 20050917" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15995196, 18459799, 20050917; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="glutaminase" /protein_id="NP_388125.1" /db_xref="EnsemblGenomes-Gn:BSU02430" /db_xref="EnsemblGenomes-Tr:CAB12037" /db_xref="GOA:O31465" /db_xref="InterPro:IPR012338" /db_xref="InterPro:IPR015868" /db_xref="PDB:1MKI" /db_xref="PDB:2OSU" /db_xref="PDB:3AGF" /db_xref="PDB:3BRM" /db_xref="SubtiList:BG12753" /db_xref="UniProtKB/Swiss-Prot:O31465" /translation="MKELIKEHQKDINPALQLHDWVEYYRPFAANGQSANYIPALGKV NDSQLGICVLEPDGTMIHAGDWNVSFTMQSISKVISFIAACMSRGIPYVLDRVDVEPT GDAFNSIIRLEINKPGKPFNPMINAGALTIASILPGESAYEKLEFLYSVMETLIGKRP RIHEEVFRSEWETAHRNRALAYYLKETNFLEAEVEETLEVYLKQCAMESTTEDIALIG LILAHDGYHPIRHEQVIPKDVAKLAKALMLTCGMYNASGKYAAFVGVPAKSGVSGGIM ALVPPSARREQPFQSGCGIGIYGPAIDEYGNSLTGGMLLKHMAQEWELSIF*" gene complement(264191..265174) /gene="glsA" /locus_tag="BSU_02430" /old_locus_tag="BSU02430" promotor_-10 complement(265268..265285) /Source="Nicolas_upshift_promotors" /id="U175" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.71028971028971" /psig="0.97002997002997" /xcortree=1548 /SigmaFactorBS="tgcttattttcaaaatgtttttgtcgtATTTTGTAtgattct gtagtctcCATTATACAGTAATTATAccttccgctattatgaaagcgtttaacgcccc c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" misc_feature 265273..265292 /Source="Nicolas_upshift_promotors" /id="U176" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.908091908091908" /psig=1 /xcortree=1812 /SigmaFactorBS="tcaaaacgaaggctaagggggcgttaaacgctttcataatag cggaaggtataaTTACTGTATAATGGAGACTAcagaatcatacaaaatacgacaaaaa c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(265275) /Source="Nicolas_upshifts" /id="U175" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.71028971028971" /psig="0.97002997002997" /xcortree=1548 /SigmaFactorBS="tgcttattttcaaaatgtttttgtcgtATTTTGTAtgattct gtagtctcCATTATACAGTAATTATAccttccgctattatgaaagcgtttaacgcccc c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" upshifts 265279 /Source="Nicolas_upshifts" /id="U176" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.908091908091908" /psig=1 /xcortree=1812 /SigmaFactorBS="tcaaaacgaaggctaagggggcgttaaacgctttcataatag cggaaggtataaTTACTGTATAATGGAGACTAcagaatcatacaaaatacgacaaaaa c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(265301..265308) /Source="Nicolas_upshift_promotors" /id="U175" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.71028971028971" /psig="0.97002997002997" /xcortree=1548 /SigmaFactorBS="tgcttattttcaaaatgtttttgtcgtATTTTGTAtgattct gtagtctcCATTATACAGTAATTATAccttccgctattatgaaagcgtttaacgcccc c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" CDS 265476..266708 /gene="glnJ" /locus_tag="BSU_02440" /old_locus_tag="BSU02440" /EC_number="2.7.13.3" /function="16.3: Control" /function="16.12: Sense" /experiment="publication(s) with functional evidences, PMID:11717295, 15995196, 17001076, 21435182, 23461034, 25691471" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11717295, 15995196, 17001076, 21435182, 23461034, 25691471; Product type rc : receptor" /codon_start=1 /transl_table=11 /product="two-component sensor histidine kinase [GlnL] forglutamine degradation" /protein_id="NP_388126.2" /db_xref="EnsemblGenomes-Gn:BSU02440" /db_xref="EnsemblGenomes-Tr:CAB12038" /db_xref="GOA:P40758" /db_xref="InterPro:IPR003594" /db_xref="InterPro:IPR004358" /db_xref="InterPro:IPR005467" /db_xref="InterPro:IPR036890" /db_xref="SubtiList:BG10871" /db_xref="UniProtKB/Swiss-Prot:P40758" /translation="MLITVPLAGELKFYPLNEEFRVSFGAPVFFFFLSLLRHVPAVLP GFLTGAAVFIFRVFLELWGGGHNGLTPILYDQASGFFFYMTYACLFSILKANRFRERP IMLGFIGFMIEVVSDCVELTVQFLIFHTVVTPEKITDIAVIAISHTFIVMSFYSVLKL YETQSREKQTRQQHEHMLMIVSNLYEETVHLKKTLKTTEKVTNDSYQLYREMKGKDVQ LSGRILRLAGEIHEVKKDNQRIFAGLSKLISNESLRDYMRASDLLQLVIRMNEKYAEA LGKQIDFYCSIEGEHDEYHVFIVLSIINNLTANAVEAMDEEGMVSLRLRKPNESMVEF QVEDNGPGISEKIGDIVFDPGFTSKYDEFGTPSTGIGLSYVKEIVTELEGDITFDNQQ RGVVFAIRLPVRHLIQKG*" gene 265476..266708 /gene="glnJ" /locus_tag="BSU_02440" /old_locus_tag="BSU02440" CDS 266719..267663 /gene="glnL" /locus_tag="BSU_02450" /old_locus_tag="BSU02450" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:11717295, 15995196" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11717295, 15995196; Product type r: regulator" /codon_start=1 /transl_table=11 /product="two-component response regulator [GlnJ] for glutamine utilisation" /protein_id="NP_388127.1" /db_xref="EnsemblGenomes-Gn:BSU02450" /db_xref="EnsemblGenomes-Tr:CAB12039" /db_xref="GOA:P40759" /db_xref="InterPro:IPR001789" /db_xref="InterPro:IPR011006" /db_xref="InterPro:IPR013972" /db_xref="SubtiList:BG10872" /db_xref="UniProtKB/Swiss-Prot:P40759" /translation="MRFFIADDDRAVRSILRQIIEDEDLGEAAGEADDGSQVEGHMLQ FKQIDILLIDLLMPGRDGIETIRQIQNTYSGKIVMISQVEAKEMVGEAYSLGIEYFIH KPINRIEIVTVLQKVKERIELEHSIGAIQHSLSRLVNRTERKARPQQKSDSGLKEAGT FLLSELGMMGEGGAHDLMAVLQYLAEHEQSEPHEKQSPSLKQIFTQVAVRKLGTGASQ TEVNREMKASEQRIRRAIIHSLHHFASLGTTDFSNPKFETYASKFFDFPVVSQKMKEL QSKDAKPLAPARINMKKFIHVFFLEAKLLHETMKQRRI*" gene 266719..267663 /gene="glnL" /locus_tag="BSU_02450" /old_locus_tag="BSU02450" downshifts 267640 /Source="Nicolas_upshifts" /id="D95" /incds=0 /nref=45 /ntot=191 /MaxReadThrough="1.43757" /MaxDrop="3.64091" /score="2.73020459" /energy="-6.2" /TU="NA" /idTUdmin="U177" /TUdmin="-484" /isTUend="FALSE" promotor_-35 267760..267767 /Source="Nicolas_upshift_promotors" /id="U177" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.982017982017982" /psig="0.999000999001" /xcortree=370 /SigmaFactorBS="gccggacagtgatttaccgcttttttataaaatatcagaaaa taaagaTATTGACTtattgtttatttgTCTTACAATTAAACAAAAGGatatatgggaa g" /listShort="S94, ycbC" /GFF_Attribute="listLong" /label="promotor_-35" S_feature 267772..267889 /Source="Nicolas_S_feature" /locus_tag="new_267772_267889" /HighExp="Sw, BC, M40t90, Etha, MG-0.2, HiTm, HiOs, G135, UNK1, MG-0.1" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S94" upshifts 267772 /Source="Nicolas_upshifts" /id="U177" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.982017982017982" /psig="0.999000999001" /xcortree=370 /SigmaFactorBS="gccggacagtgatttaccgcttttttataaaatatcagaaaa taaagaTATTGACTtattgtttatttgTCTTACAATTAAACAAAAGGatatatgggaa g" /listShort="S94, ycbC" /GFF_Attribute="listLong" promotor_-10 267781..267800 /Source="Nicolas_upshift_promotors" /id="U177" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.982017982017982" /psig="0.999000999001" /xcortree=370 /SigmaFactorBS="gccggacagtgatttaccgcttttttataaaatatcagaaaa taaagaTATTGACTtattgtttatttgTCTTACAATTAAACAAAAGGatatatgggaa g" /listShort="S94, ycbC" /GFF_Attribute="listLong" /label="promotor_-10" CDS 267890..268816 /gene="kdgD" /locus_tag="BSU_02460" /old_locus_tag="BSU02460" /EC_number="4.2.1.41" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 12044674; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="5-dehydro-4-deoxyglucarate dehydratase" /protein_id="NP_388128.2" /db_xref="EnsemblGenomes-Gn:BSU02460" /db_xref="EnsemblGenomes-Tr:CAB12040" /db_xref="GOA:P42235" /db_xref="InterPro:IPR002220" /db_xref="InterPro:IPR013785" /db_xref="InterPro:IPR017655" /db_xref="SubtiList:BG11158" /db_xref="UniProtKB/Swiss-Prot:P42235" /translation="MSRIRKAPAGILGFPVAPFNTQGKLEEEALFQNIEFLLNEGLEA IFIACGSGEFQSLSQKEYEQMVEVAVSAAGGKVPVYTGVGGNLSTALDWAQLSEKKGA DGYLILPPYLVHGEQEGLYQYAKTIIESTDLNAILYQRDNAVLSVEQIKRLTECEQLV GVKDGVGNMDLNINLVYTIGDRLGWLNGMPMAEVTMPAYLPIGFHSYSSAISNYIPHI SRMFYDALKNGNDELVKELYRHVILPINDIRKQRKGYAVSLIKAGMEIMGLNVRNTAR PPVGPVEKDHYQQLEAILKQAADRFPKKAATV*" gene 267890..268816 /gene="kdgD" /locus_tag="BSU_02460" /old_locus_tag="BSU02460" CDS 268846..270312 /gene="gucD" /locus_tag="BSU_02470" /old_locus_tag="BSU02470" /EC_number="1.2.1.26" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 12044674, 17202142; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="2,5-dioxovalerate dehydrogenase (alpha-ketoglutaric semialdehyde dehydrogenase)" /protein_id="NP_388129.1" /db_xref="EnsemblGenomes-Gn:BSU02470" /db_xref="EnsemblGenomes-Tr:CAB12041" /db_xref="GOA:P42236" /db_xref="InterPro:IPR015590" /db_xref="InterPro:IPR016160" /db_xref="InterPro:IPR016161" /db_xref="InterPro:IPR016162" /db_xref="InterPro:IPR029510" /db_xref="SubtiList:BG11159" /db_xref="UniProtKB/Swiss-Prot:P42236" /translation="MSVITEQNTYLNFINGEWVKSQSGDMVKVENPADVNDIVGYVQN STAEDVERAVTAANEAKTAWRKLTGAERGQYLYKTADIMEQRLEEIAACATREMGKTL PEAKGETARGIAILRYYAGEGMRKTGDVIPSTDKDALMFTTRVPLGVVGVISPWNFPV AIPIWKMAPALVYGNTVVIKPATETAVTCAKIIACFEEAGLPAGVINLVTGPGSVVGQ GLAEHDGVNAVTFTGSNQVGKIIGQAALARGAKYQLEMGGKNPVIVADDADLEAAAEA VITGAFRSTGQKCTATSRVIVQSGIYERFKEKLLQRTKDITIGDSLKEDVWMGPIASK NQLDNCLSYIEKGKQEGASLLIGGEKLENGKYQNGYYVQPAIFDNVTSEMTIAQEEIF GPVIALIKVDSIEEALNIANDVKFGLSASIFTENIGRMLSFIDEIDAGLVRINAESAG VELQAPFGGMKQSSSHSREQGEAAKDFFTAIKTVFVKP*" gene 268846..270312 /gene="gucD" /locus_tag="BSU_02470" /old_locus_tag="BSU02470" CDS 270396..271763 /gene="gudP" /locus_tag="BSU_02480" /old_locus_tag="BSU02480" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:12044674, 15849754, 16850406" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12044674, 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="glucarate transporter" /protein_id="NP_388130.2" /db_xref="EnsemblGenomes-Gn:BSU02480" /db_xref="EnsemblGenomes-Tr:CAB12042" /db_xref="GOA:P42237" /db_xref="InterPro:IPR000849" /db_xref="InterPro:IPR004744" /db_xref="InterPro:IPR011701" /db_xref="InterPro:IPR020846" /db_xref="InterPro:IPR036259" /db_xref="SubtiList:BG11160" /db_xref="UniProtKB/Swiss-Prot:P42237" /translation="MKKDFASVTPAGKKTSVRWFIVFMLFLVTSINYADRATLSITGD SVQHDLGLDSVAMGYVFSAFGWAYVIGQLPGGWLLDRFGSKTIIALSIFFWSFFTLLQ GAIGFFSAGTAIILLFALRFLVGLSEAPSFPGNGRVVASWFPSSERGTASAFFNSAQY FAIVIFSPLMGWLTHSFGWHSVFVVMGIAGILLAVIWLKTVYEPKKHPKVNEAELAYI EQGGGLISMDDSKSKQETESKWPYIKQLLTNRMLIGVYIAQYCITTLTYFFLTWFPVY LVQARGMSILEAGFVASLPALCGFAGGVLGGIVSDILLKKGRSLTFARKVPIIAGMLL SCSMIVCNYTDSAWLVVVIMSLAFFGKGFGALGWAVVSDTSPKECAGLSGGLFNTFGN IASITTPIIIGYIVNATGSFNGALVFVGANAIAAILSYLLLVGPIKRVVLKKQEQDPD QSLPV*" gene 270396..271763 /gene="gudP" /locus_tag="BSU_02480" /old_locus_tag="BSU02480" CDS 271800..273167 /gene="gudD" /locus_tag="BSU_02490" /old_locus_tag="BSU02490" /EC_number="4.2.1.40" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 9772161, 12044674; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="glucarate dehydratase" /protein_id="NP_388131.2" /db_xref="EnsemblGenomes-Gn:BSU02490" /db_xref="EnsemblGenomes-Tr:CAB12043" /db_xref="GOA:P42238" /db_xref="InterPro:IPR013342" /db_xref="InterPro:IPR017653" /db_xref="InterPro:IPR029017" /db_xref="InterPro:IPR029065" /db_xref="InterPro:IPR034390" /db_xref="InterPro:IPR034598" /db_xref="InterPro:IPR036849" /db_xref="SubtiList:BG11161" /db_xref="UniProtKB/Swiss-Prot:P42238" /translation="MSSPIQEQVQKEKRSNIPSISEMKVIPVAGHDSMLLNLSGAHSP FFTRNIVILTDSSGNQGVGEVPGGEHIRRTLELSEPLVVGKSIGAYQAILQTVRKQFG DQDRGGRGNQTFDLRTTVHAVTALEAALLDLLGKFLQEPVAALLGEGKQRDEVKMLGY LFYIGDRNRTTLPYQSDEQSDCAWFRLRHEEALTPEAIVRLAESAQERYGFQDFKLKG GVLRGEEEIEAVTALSKRFPEARITLDPNGAWSLEEAIALCKGKQDVLAYAEDPCGDE NGYSAREVMAEFRRATGLPTATNMIATDWREMGHAIQLHAVDIPLADPHFWTMQGSVR VAQMCHDWGLTWGSHSNNHFDISLAMFTHVAAAAPGRITAIDTHWIWQDGQRLTKQPF EISSGCVKVPDKPGLGVDIDMEQVEKAHEIYRKMNLGARNDAIPMQFLISNWEFDRKR PCLVR*" gene 271800..273167 /gene="gudD" /locus_tag="BSU_02490" /old_locus_tag="BSU02490" promotor_-35 273181..273188 /Source="Nicolas_upshift_promotors" /id="U178" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.586413586413586" /psig="0.999000999001" /xcortree=2135 /SigmaFactorBS="gcgcccgtgtcttgtgcgataagtttgattgtaaaTATTGTC AtatccgctattttgTCTTACAATTGAACAACTgaagggagagttgttcgtgtacgaa g" /listShort="ycbG, garD" /listLong="S95, ycbJ, NA" /label="promotor_-35" promotor_-10 273203..273220 /Source="Nicolas_upshift_promotors" /id="U178" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.586413586413586" /psig="0.999000999001" /xcortree=2135 /SigmaFactorBS="gcgcccgtgtcttgtgcgataagtttgattgtaaaTATTGTC AtatccgctattttgTCTTACAATTGAACAACTgaagggagagttgttcgtgtacgaa g" /listShort="ycbG, garD" /listLong="S95, ycbJ, NA" /label="promotor_-10" upshifts 273206 /Source="Nicolas_upshifts" /id="U178" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.586413586413586" /psig="0.999000999001" /xcortree=2135 /SigmaFactorBS="gcgcccgtgtcttgtgcgataagtttgattgtaaaTATTGTC AtatccgctattttgTCTTACAATTGAACAACTgaagggagagttgttcgtgtacgaa g" /listShort="ycbG, garD" /listLong="S95, ycbJ, NA" CDS 273237..273938 /gene="garR" /locus_tag="BSU_02500" /old_locus_tag="BSU02500" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:12044674" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12044674; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator (GntR family)" /protein_id="NP_388132.2" /db_xref="EnsemblGenomes-Gn:BSU02500" /db_xref="EnsemblGenomes-Tr:CAB12044" /db_xref="GOA:P42239" /db_xref="InterPro:IPR000524" /db_xref="InterPro:IPR008920" /db_xref="InterPro:IPR011711" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG11162" /db_xref="UniProtKB/Swiss-Prot:P42239" /translation="MYEGLEDLKVDTVNRKTLAKQVIERIVHLLSSGQLRAGDKLPTE MELMDILHVSRPVLREALSSLETLGVITRKTRGGTYFNDKIGMQPFSVMLALATDNLP AIIEARMALELGLVTIAAEKINEEELQRLQKTIDDIANSTDNHYGEADKEFHRIIALS ANNPVVEGMIQSLLITHAKIDSQIPYRERDVTVEYHKKIYDALAKRDPYKAHYHMYEH LKFVRDKILKGMDEK*" gene 273237..273938 /gene="garR" /locus_tag="BSU_02500" /old_locus_tag="BSU02500" downshifts 273888 /Source="Nicolas_upshifts" /id="D96" /incds=0 /nref=1 /ntot=35 /MaxReadThrough="3.59234" /MaxDrop="2.3923" /score="4.10541728" /energy="-9.5" /TU="U178" /idTUdmin="U178" /TUdmin="-1694" /isTUend="FALSE" downshifts 273932 /Source="Nicolas_upshifts" /id="D97" /incds=0 /nref=1 /ntot=82 /MaxReadThrough="3.21794" /MaxDrop="2.49226" /score="4.10541728" /energy="-9.5" /TU="U178" /idTUdmin="U178" /TUdmin="-1650" /isTUend="FALSE" CDS 274029..275561 /gene="garD" /locus_tag="BSU_02510" /old_locus_tag="BSU02510" /EC_number="4.2.1.42" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 9772162; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="D-galactarate dehydratase" /protein_id="NP_388133.2" /db_xref="EnsemblGenomes-Gn:BSU02510" /db_xref="EnsemblGenomes-Tr:CAB12045" /db_xref="GOA:P42240" /db_xref="InterPro:IPR007392" /db_xref="InterPro:IPR013974" /db_xref="InterPro:IPR017654" /db_xref="SubtiList:BG11163" /db_xref="UniProtKB/Swiss-Prot:P42240" /translation="MAMNLRKNQAPLYIKVHEIDNTAIIVNDGGLPKGTVFSCGLVLE EDVPQGHKVALTDLNQGDEIVRYGEVIGFADETIKRGSWIREALVRMPAPPALDDLPL ANRVPQPRPPLEGYTFEGYRNADGSAGTKNILGITTSVQCVVGVLDYAVKRIKEELLP KYPNVDDVVPLHHQYGCGVAINAPDAVIPIRTIQNLAKHPNFGGEVMVIGLGCEKLLP ERIASENDDDILSLQDHRGFAAMIQSILEMAEERLIRLNSRTRVSCPVSDLVIGLQCG GSDAFSGVTANPAVGYAADLLVRAGATVLFSEVTEVRDAIHLLTPRAVSEEVGQSLIK EMKWYDSYLRRGDADRSANPSPGNKKGGLSNVVEKALGSVAKSGTSPISGVLGPGERA KQKGLLFAATPASDFVCGTLQLAAGMNLQVFTTGRGTPYGLAAAPVLKVSTRHSLSEH WADLIDINAGRIATGEASIEDVGWEIFRTILDVASGRKQTWADRWGLHNDLCLFNPAP VT*" gene 274029..275561 /gene="garD" /locus_tag="BSU_02510" /old_locus_tag="BSU02510" promotor_-35 275573..275576 /Source="Nicolas_upshift_promotors" /id="U179" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.927072927072927" /psig=1 /xcortree=422 /SigmaFactorBS="tcctgctccagtgacttgattcatgtttttATAGcggaaaga tggaatATGCTGTAAAATGAAAATCAgcgtataggaaacggaggggttacagcatggc a" /listShort="S95, ycbJ, NA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 275591..275610 /Source="Nicolas_upshift_promotors" /id="U179" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.927072927072927" /psig=1 /xcortree=422 /SigmaFactorBS="tcctgctccagtgacttgattcatgtttttATAGcggaaaga tggaatATGCTGTAAAATGAAAATCAgcgtataggaaacggaggggttacagcatggc a" /listShort="S95, ycbJ, NA" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 275603..275837 /Source="Nicolas_S_feature" /locus_tag="new_275603_275837" /HighExp="LoTm, Sw, BC, BI, B60, B36, T3.30H, T5.0H, T4.0H, T3.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.50265400000000005" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="SigA" /TUlongPSig="0.999" /label="S95" upshifts 275603 /Source="Nicolas_upshifts" /id="U179" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.927072927072927" /psig=1 /xcortree=422 /SigmaFactorBS="tcctgctccagtgacttgattcatgtttttATAGcggaaaga tggaatATGCTGTAAAATGAAAATCAgcgtataggaaacggaggggttacagcatggc a" /listShort="S95, ycbJ, NA" /GFF_Attribute="listLong" CDS 275838..276758 /gene="ycbJ" /locus_tag="BSU_02520" /old_locus_tag="BSU02520" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 12044674; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative phosphotransferase" /protein_id="NP_388134.1" /db_xref="EnsemblGenomes-Gn:BSU02520" /db_xref="EnsemblGenomes-Tr:CAB12046" /db_xref="GOA:P42242" /db_xref="InterPro:IPR002575" /db_xref="InterPro:IPR011009" /db_xref="SubtiList:BG11165" /db_xref="UniProtKB/Swiss-Prot:P42242" /translation="MTNLNEKQLITEIVGLARSQGLTVHSENAQLNETGMDFQVVFAK DDTGMPWVLRKPRRSDVVERASAEGITLAFLRANLTADVPDWRIHTPELIAYPMLKGT PAAGIDLEQKQYVWNMDHQPPSDDFVRTLADILAELHGTDQISAGQSGIEVIRPEDFR QMTADSMVDVKNKLGVSTTLWERWQKWVDDDAYWPGFSSLIHGDLHPPHILIDQNGRV TGLLDWTEAKVADPAKDFVLYQTIFGEKETARLLEYYDQAGGRIWAKMQEHISEMQAA YPVEIAKLALQTQQEEHINMALEALGVTSD*" gene 275838..276758 /gene="ycbJ" /locus_tag="BSU_02520" /old_locus_tag="BSU02520" promotor_-35 276760..276767 /Source="Nicolas_upshift_promotors" /id="U180" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.869130869130869" /psig=1 /xcortree=572 /SigmaFactorBS="gaagcacttggtgtaacatcggattaagAATTGACTtcgttt catgaaccGAGTATTATAAACTCTACAAataatagaacggattaacaatcgtgaggaa g" /listShort="NA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 276782..276801 /Source="Nicolas_upshift_promotors" /id="U180" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.869130869130869" /psig=1 /xcortree=572 /SigmaFactorBS="gaagcacttggtgtaacatcggattaagAATTGACTtcgttt catgaaccGAGTATTATAAACTCTACAAataatagaacggattaacaatcgtgaggaa g" /listShort="NA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 276792 /Source="Nicolas_upshifts" /id="U180" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.869130869130869" /psig=1 /xcortree=572 /SigmaFactorBS="gaagcacttggtgtaacatcggattaagAATTGACTtcgttt catgaaccGAGTATTATAAACTCTACAAataatagaacggattaacaatcgtgaggaa g" /listShort="NA" /GFF_Attribute="listLong" misc_RNA 276815..277062 /gene="tboW" /locus_tag="BSU_misc_RNA_6" /product="T-box riboswitch specific of tryptophan tRNA ligase" /experiment="publication(s) with functional evidences, PMID:1317842, 9098041, 10706627, 12165569, 12547201" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1317842, 9098041, 10706627, 12165569, 12547201; Product type n: RNA" gene 276815..277062 /gene="tboW" /locus_tag="BSU_misc_RNA_6" downshifts 277031 /Source="Nicolas_upshifts" /id="D98" /incds=0 /nref=225 /ntot=264 /MaxReadThrough="2.36361" /MaxDrop="6.52913" /score="36.5571172" /energy="-16.6" /TU="NA" /idTUdmin="U179" /TUdmin="-3" /isTUend="TRUE" CDS 277160..277321 /gene="rtpA" /locus_tag="BSU_02530" /old_locus_tag="BSU02530" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:10706627, 11557884, 12855807, 15099736, 15213402, 15743934, 16306262" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10706627, 11557884, 12855807, 15099736, 15213402, 15743934, 16306262; Product type r: regulator" /codon_start=1 /transl_table=11 /product="anti-TRAP regulator" /protein_id="NP_388135.1" /db_xref="EnsemblGenomes-Gn:BSU02530" /db_xref="EnsemblGenomes-Tr:CAB12047" /db_xref="GOA:O31466" /db_xref="InterPro:IPR031538" /db_xref="InterPro:IPR036410" /db_xref="PDB:2BX9" /db_xref="PDB:2KO8" /db_xref="PDB:2ZP8" /db_xref="PDB:2ZP9" /db_xref="SubtiList:BG12776" /db_xref="UniProtKB/Swiss-Prot:O31466" /translation="MVIATDDLEVACPKCERAGEIEGTPCPACSGKGVILTAQGYTLL DFIQKHLNK*" gene 277160..277321 /gene="rtpA" /locus_tag="BSU_02530" /old_locus_tag="BSU02530" promotor_no_box 277238..277338 /Source="Nicolas_upshift_promotors" /id="U181" /multdbtbs="-" /comp="M21" /sig="Sig-" /pcomp="0.544455544455544" /psig="0.010989010989011" /xcortree=1479 /SigmaFactorBS="ccggcctgcagcggaaaaggtgttattctgactgctcaagga tatacgcttctcgattttatccaaaagcatttgaataagtaaaggagaaaagctgagc t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_no_box" upshifts 277298 /Source="Nicolas_upshifts" /id="U181" /multdbtbs="-" /comp="M21" /sig="Sig-" /pcomp="0.544455544455544" /psig="0.010989010989011" /xcortree=1479 /SigmaFactorBS="ccggcctgcagcggaaaaggtgttattctgactgctcaagga tatacgcttctcgattttatccaaaagcatttgaataagtaaaggagaaaagctgagc t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" CDS 277342..278280 /gene="ycbK" /locus_tag="BSU_02540" /old_locus_tag="BSU02540" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 10706627, 15063849, 15849754, 16850406, 16879415, 17114263; Product type t : transporter" /codon_start=1 /transl_table=11 /product="putative tryptophan or indole exporter" /protein_id="NP_388136.1" /db_xref="EnsemblGenomes-Gn:BSU02540" /db_xref="EnsemblGenomes-Tr:CAB12048" /db_xref="GOA:P42243" /db_xref="InterPro:IPR000620" /db_xref="SubtiList:BG11166" /db_xref="UniProtKB/Swiss-Prot:P42243" /translation="MRAEEQSKIREAAAGTIFLLIGTVCFASKSIWIKWAYQMGAEPD AVLLYRQLLAVPLFWLIFLIYRPPMPDGKKKGDLWKACGAGVFCFFLSPLLDFIGLNH VSAMVERILLMSYPLFVFGFTACRDRKMSSIQDLFAVLAVMFGLFLALGGWNAELFQA NMIGAVFILLSSAVYAGYLVLSGHLVHQIGGIRLNAYGMTAAGAAMMLYTGIKSAAGM NTPMAAYPLSMYGLFAVIAVVTTVIPFVLMLEGIKRIGAQRAAAISMAGPILTIFYGA LFLGERLGLIQVIGCGGVFFVITGMEYRKLKTGKKE*" gene 277342..278280 /gene="ycbK" /locus_tag="BSU_02540" /old_locus_tag="BSU02540" downshifts 277386 /Source="Nicolas_upshifts" /id="D99" /incds=0 /nref=1 /ntot=7 /MaxReadThrough="3.05417" /MaxDrop="3.72787" /score="0.773303272" /energy="-9" /TU="NA" /idTUdmin="U181" /TUdmin=0 /isTUend="TRUE" misc_feature 278303..278322 /Source="Nicolas_upshift_promotors" /id="U182" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.699300699300699" /psig="0.998001998001998" /xcortree=2265 /SigmaFactorBS="tacaggaagctgaaaacaggaaaaaaagaataatttttataa aacacacacgtttTTCAATTACAATAAGTGTAAttacgtgtgtgttttttgattttgt a" /listShort="S96, ycbL, ycbM" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" S_feature 278308..278376 /Source="Nicolas_S_feature" /locus_tag="new_278308_278376" /HighExp="C90, dia5, Lbtran, Lbexp, LBGexp, SMM, dia0, dia15, BMM, T-3.40H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.998" /TUlongSig="NA" /TUlongPSig="NA" /label="S96" upshifts 278308 /Source="Nicolas_upshifts" /id="U182" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.699300699300699" /psig="0.998001998001998" /xcortree=2265 /SigmaFactorBS="tacaggaagctgaaaacaggaaaaaaagaataatttttataa aacacacacgtttTTCAATTACAATAAGTGTAAttacgtgtgtgttttttgattttgt a" /listShort="S96, ycbL, ycbM" /GFF_Attribute="listLong" CDS 278377..279057 /gene="ycbL" /locus_tag="BSU_02550" /old_locus_tag="BSU02550" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:11717295" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11717295; Product type r: regulator" /codon_start=1 /transl_table=11 /product="two-component response regulator [YcbM]" /protein_id="NP_388137.2" /db_xref="EnsemblGenomes-Gn:BSU02550" /db_xref="EnsemblGenomes-Tr:CAB12049" /db_xref="GOA:P42244" /db_xref="InterPro:IPR001789" /db_xref="InterPro:IPR001867" /db_xref="InterPro:IPR011006" /db_xref="InterPro:IPR016032" /db_xref="InterPro:IPR036388" /db_xref="SubtiList:BG11167" /db_xref="UniProtKB/Swiss-Prot:P42244" /translation="MLVEDDHSISEMVDHYLTKEGFGIVHAFDGEEGIRLFQQGSYDL VLLDIMLPKLNGMDFLKIIREKSNIPVLMISAKDGDVDKALGLGFGADDYIAKPFSMI ELTARVKAAIRRATQYSAEEPAVNKVIRIHQLAIDIDNVSVLKNGEPLQLTSTEWQLL CLFASNPKKVFTKEQIYRSVWNEEYFDDQNIINVHMRRLREKIEDDPSSPQYIKTLWG IGYKLGEF*" gene 278377..279057 /gene="ycbL" /locus_tag="BSU_02550" /old_locus_tag="BSU02550" CDS 279059..279994 /gene="ycbM" /locus_tag="BSU_02560" /old_locus_tag="BSU02560" /function="16.3: Control" /function="16.12: Sense" /experiment="publication(s) with functional evidences, PMID:11717295" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11717295; Product type rc: receptor" /codon_start=1 /transl_table=11 /product="two-component sensor histidine kinase [YcbL]" /protein_id="NP_388138.2" /db_xref="EnsemblGenomes-Gn:BSU02560" /db_xref="EnsemblGenomes-Tr:CAB12050" /db_xref="GOA:P42245" /db_xref="InterPro:IPR003594" /db_xref="InterPro:IPR003661" /db_xref="InterPro:IPR004358" /db_xref="InterPro:IPR005467" /db_xref="InterPro:IPR036097" /db_xref="InterPro:IPR036890" /db_xref="SubtiList:BG11168" /db_xref="UniProtKB/Swiss-Prot:P42245" /translation="MTVLWVAAVIALACLNVIQFIMKKKRDGNLAYTADQLSYMLSRD SAGQILLPTDDHALKDLLVNINLIVENRQQISAQFAKTEQSMKRMLTNMSHDLKTPLT VILGYIEAIQSDPNMPDEERERLLGKLRQKTNELIQMINSFFDLAKLESEDKEIPITK VHMNDICKRNILHYYDAVQSKGFQAAIDIPDTPVYAQANEEALDRILQNLLSNAIQYG AAGKLIGLTLSYDERNIAITVWDRGKGISETDQQRVFERLYTLEESRNKAFQGSGLGL TITKRLTEKMGGIISVQSKPYERTAFTITLKRMTY*" gene 279059..279994 /gene="ycbM" /locus_tag="BSU_02560" /old_locus_tag="BSU02560" CDS 280086..281009 /gene="ycbN" /locus_tag="BSU_02570" /old_locus_tag="BSU02570" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 12486040; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative ABC efflux transporter (ATP-binding protein)" /protein_id="NP_388139.2" /db_xref="EnsemblGenomes-Gn:BSU02570" /db_xref="EnsemblGenomes-Tr:CAB12051" /db_xref="GOA:P42246" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR017871" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG11169" /db_xref="UniProtKB/Swiss-Prot:P42246" /translation="MTYIVQTNGLTKTYQGKEVVSNVSMHIKKGEIYGFLGPNGAGKT TIMKMLTSLVKPTSGEIIILGNKFTHTSYEVLGNIGSMIEYPIFYENLTAEENLDLHC EYMGYHNKKAIQEVLDMVNLKQIDKKPVKTFSLGMKQRLGIARAILTKPDLLILDEPV NGLDPLGIKKIRQLFQVLSKEYGMTLLISSHLLGEIEQIADTIGVIRDGRLLEEVSME DVRGQNTEYIELVTPNQTRACFVLEKELQLTNFKILNEKTIRIYEAEASQAAISKALI LNDVDIESMNKKYTSLEDYFIKLINGNSISA*" gene 280086..281009 /gene="ycbN" /locus_tag="BSU_02570" /old_locus_tag="BSU02570" S_feature complement(280556..281740) /Source="Nicolas_S_feature" /locus_tag="new_280556_281740_c" /HighExp="Etha, Sw, Gly, B36, LoTm, B60, GM 150, Salt, C30, ferm" /AntisenseName="ycbO" /AntisenseCor="-0.38911425676406203" /AntisenseRegPval="-10.4" /CDS_PredictionProba="NA" /TUshortSig="SigB" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S97" CDS 281028..281714 /gene="ycbO" /locus_tag="BSU_02580" /old_locus_tag="BSU02580" /function="16.1: Circulate" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative Na+-driven exporter" /protein_id="NP_388140.3" /db_xref="EnsemblGenomes-Gn:BSU02580" /db_xref="EnsemblGenomes-Tr:CAB12052" /db_xref="GOA:P42247" /db_xref="InterPro:IPR032688" /db_xref="SubtiList:BG11170" /db_xref="UniProtKB/Swiss-Prot:P42247" /translation="MNLIRIELRKMKMGWYIRGALIANVIIMGFMWLISYSEKADGGV SFQSTDEAFLIIGTFVRAVFIVFGAVLIVKLVISEYKNKTILVMFTYPISRKKLLTAK LMIAGGLTFITILLSNILIAAGFFWLNSICHFIPGELTSEIISQQAVKMAVFAFGAAG TSLVPIFFGMRRHSVPATIISSVVIVMLISSTSPGFSISSVVYIPLSLAAFGLFFSYM AIRNADKQDA*" gene 281028..281714 /gene="ycbO" /locus_tag="BSU_02580" /old_locus_tag="BSU02580" CDS complement(281675..281809) /locus_tag="BSU_02585" /old_locus_tag="BSU02585" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_009513940.1" /translation="MARSIILKQEQTHNGKAGADSIGLLYILGAFVYASCLSAFLIAM *" gene complement(281675..281809) /locus_tag="BSU_02585" /old_locus_tag="BSU02585" downshifts 281709 /Source="Nicolas_upshifts" /id="D100" /incds=0 /nref=8 /ntot=120 /MaxReadThrough="1.13131" /MaxDrop="3.44039" /score="18.1873505" /energy="-11.4" /TU="NA" /idTUdmin="U184" /TUdmin="-1166" /isTUend="FALSE" CDS complement(281769..282155) /gene="ycbP" /locus_tag="BSU_02590" /old_locus_tag="BSU02590" /function="16.13: Shape" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406, 22582280; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative inner integral membrane protein" /protein_id="NP_388141.1" /db_xref="EnsemblGenomes-Gn:BSU02590" /db_xref="EnsemblGenomes-Tr:CAB12053" /db_xref="GOA:P42248" /db_xref="InterPro:IPR019649" /db_xref="SubtiList:BG11171" /db_xref="UniProtKB/Swiss-Prot:P42248" /translation="MTHVKALAIKGIMTIIVLYLVLGLGFGFTFGDTLLMTIVLGVIS YLLGDLYVLPKWNNMIATLADFGLAFLVIWLMGMPLSMGMTGGEVALAALFGAIVMAI GEYCFHFYMMSKEIGKKHYLETRTDS*" gene complement(281769..282155) /gene="ycbP" /locus_tag="BSU_02590" /old_locus_tag="BSU02590" downshifts complement(281785) /Source="Nicolas_upshifts" /id="D101" /incds=0 /nref=148 /ntot=217 /MaxReadThrough="6.64196" /MaxDrop="7.40353" /score="13.8182557" /energy="-15.6" /TU="U183" /idTUdmin="U185" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(282181..282199) /Source="Nicolas_upshift_promotors" /id="U183" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=164 /SigmaFactorBS="ctctccccagcagatttgcacccgcctccgaaaagaaataaG GTTTAActttttacatttgAGGAATTATACATAACAAAtcaaatgacaaaaggaggaa t" /listShort="ycbP, S97" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(282200) /Source="Nicolas_upshifts" /id="U183" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=164 /SigmaFactorBS="ctctccccagcagatttgcacccgcctccgaaaagaaataaG GTTTAActttttacatttgAGGAATTATACATAACAAAtcaaatgacaaaaggaggaa t" /listShort="ycbP, S97" /GFF_Attribute="listLong" promotor_-35 complement(282213..282219) /Source="Nicolas_upshift_promotors" /id="U183" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=164 /SigmaFactorBS="ctctccccagcagatttgcacccgcctccgaaaagaaataaG GTTTAActttttacatttgAGGAATTATACATAACAAAtcaaatgacaaaaggaggaa t" /listShort="ycbP, S97" /GFF_Attribute="listLong" /label="promotor_-35" S_feature complement(282233..283231) /Source="Nicolas_S_feature" /locus_tag="new_282233_283231_c" /HighExp="GM 150, T0.30H, C30, T1.30H, T1.0H, T-0.40H, T-3.40H, T2.0H, T2.30H, T-4.40H" /AntisenseName="cwlJ" /AntisenseCor="0.11463160303596701" /AntisenseRegPval="-1.2" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.975" /TUlongSig="NA" /TUlongPSig="NA" /label="S98" downshifts complement(282276) /Source="Nicolas_upshifts" /id="D102" /incds=0 /nref=3 /ntot=10 /MaxReadThrough="5.23914" /MaxDrop="3.14515" /score="13.8182557" /energy="-15.6" /TU="U185,U187" /idTUdmin="U185" /TUdmin="-491" /isTUend="FALSE" promotor_-35 282412..282417 /Source="Nicolas_upshift_promotors" /id="U184" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp="0.986013986013986" /psig="0.986013986013986" /xcortree=1108 /SigmaFactorBS="gtttttagatgaataaatttaaaaacttctcctgtccctccG TCATCacttctgaagtaatgAAATATGATGAAAAGAGATcaaggggaggtgacgtgat g" /listShort="cwlJ" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 282431 /Source="Nicolas_upshifts" /id="U184" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp="0.986013986013986" /psig="0.986013986013986" /xcortree=1108 /SigmaFactorBS="gtttttagatgaataaatttaaaaacttctcctgtccctccG TCATCacttctgaagtaatgAAATATGATGAAAAGAGATcaaggggaggtgacgtgat g" /listShort="cwlJ" /GFF_Attribute="listLong" promotor_-10 282433..282451 /Source="Nicolas_upshift_promotors" /id="U184" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp="0.986013986013986" /psig="0.986013986013986" /xcortree=1108 /SigmaFactorBS="gtttttagatgaataaatttaaaaacttctcctgtccctccG TCATCacttctgaagtaatgAAATATGATGAAAAGAGATcaaggggaggtgacgtgat g" /listShort="cwlJ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(282445) /Source="Nicolas_upshifts" /id="U185" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.999000999001" /psig=0 /xcortree=680 /SigmaFactorBS="aatcgacatccgcactcgttgctctcacgaccGCCATcacgt caCCTCCCCTTGATCTCttttcatcatatttcattacttcagaagtgatgacggaggg a" /listShort="ycbP" /GFF_Attribute="listLong" promotor_-10 complement(282447..282461) /Source="Nicolas_upshift_promotors" /id="U185" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.999000999001" /psig=0 /xcortree=680 /SigmaFactorBS="aatcgacatccgcactcgttgctctcacgaccGCCATcacgt caCCTCCCCTTGATCTCttttcatcatatttcattacttcagaagtgatgacggaggg a" /listShort="ycbP" /GFF_Attribute="listLong" /label="promotor_-10" downshifts complement(282467) /Source="Nicolas_upshifts" /id="D103" /incds=0 /nref=2 /ntot=5 /MaxReadThrough="5.64474" /MaxDrop="3.76775" /score="13.8182557" /energy="-15.6" /TU="U187" /idTUdmin="U185" /TUdmin="-682" /isTUend="FALSE" promotor_-35 complement(282469..282473) /Source="Nicolas_upshift_promotors" /id="U185" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.999000999001" /psig=0 /xcortree=680 /SigmaFactorBS="aatcgacatccgcactcgttgctctcacgaccGCCATcacgt caCCTCCCCTTGATCTCttttcatcatatttcattacttcagaagtgatgacggaggg a" /listShort="ycbP" /GFF_Attribute="listLong" /label="promotor_-35" CDS 282469..282897 /gene="cwlJ" /locus_tag="BSU_02600" /old_locus_tag="BSU02600" /function="16.5: Explore" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:9515903, 11466292, 11807087, 12177332, 16936016, 26190134, 28333204" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9515903, 11466292, 11807087, 12177332, 16936016, 26190134, 28333204; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="spore cortex cell wall hydrolase" /protein_id="NP_388142.2" /db_xref="EnsemblGenomes-Gn:BSU02600" /db_xref="EnsemblGenomes-Tr:CAB12054" /db_xref="GOA:P42249" /db_xref="InterPro:IPR011105" /db_xref="SubtiList:BG11172" /db_xref="UniProtKB/Swiss-Prot:P42249" /translation="MAVVRATSADVDLMARLLRAEAEGEGKQGMLLVGNVGINRLRAN CSDFKGLRTIRQMIYQPHAFEAVTHGYFYQRARDSERALARRSINGERRWPAKFSLWY FRPQGDCPAQWYNQPFVARFKSHCFYQPTAETCENVYNTF*" gene 282469..282897 /gene="cwlJ" /locus_tag="BSU_02600" /old_locus_tag="BSU02600" downshifts 282876 /Source="Nicolas_upshifts" /id="D104" /incds=0 /nref=44 /ntot=63 /MaxReadThrough="2.30044" /MaxDrop="5.89045" /score="18.1873505" /energy="-11.4" /TU="NA" /idTUdmin="U184" /TUdmin=1 /isTUend="TRUE" promotor_-35 282942..282948 /Source="Nicolas_upshift_promotors" /id="U186" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.535464535464535" /psig="0.973026973026973" /xcortree=1784 /SigmaFactorBS="ggacaccgttcaaattgaacggtgtttttctttgaaaagATG CAATgcaaaatattccTGTGAGATAATCAAAGAAAAaagagctgacggagatgacaga a" /listShort="ycbR" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 282961..282980 /Source="Nicolas_upshift_promotors" /id="U186" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.535464535464535" /psig="0.973026973026973" /xcortree=1784 /SigmaFactorBS="ggacaccgttcaaattgaacggtgtttttctttgaaaagATG CAATgcaaaatattccTGTGAGATAATCAAAGAAAAaagagctgacggagatgacaga a" /listShort="ycbR" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 282963 /Source="Nicolas_upshifts" /id="U186" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.535464535464535" /psig="0.973026973026973" /xcortree=1784 /SigmaFactorBS="ggacaccgttcaaattgaacggtgtttttctttgaaaagATG CAATgcaaaatattccTGTGAGATAATCAAAGAAAAaagagctgacggagatgacaga a" /listShort="ycbR" /GFF_Attribute="listLong" CDS 283003..283734 /gene="ycbR" /locus_tag="BSU_02610" /old_locus_tag="BSU02610" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_388143.2" /db_xref="EnsemblGenomes-Gn:BSU02610" /db_xref="EnsemblGenomes-Tr:CAB12055" /db_xref="InterPro:IPR002035" /db_xref="InterPro:IPR019303" /db_xref="InterPro:IPR036465" /db_xref="SubtiList:BG11173" /db_xref="UniProtKB/Swiss-Prot:P42250" /translation="MATIDLQKKSVKIVLEKKQLTKVTARVGLVLDITGSMRPLYKNG TVQNVVERILAVADQFDDNGLLDVWVYDNEFSRLKPVSEKDFSGYVDREILNNDRLHK FGRNDEPPVMKDVLRKYVTEEPSSYPAFIVFINDGGCKKSIKPIIEASSDKPVFWQFV GIGNGNFDFLNKLDTLEGRVIDNTNFLHIEEIDRISDDELYDALLAEFPFWLKEAKEK GIVREQEPPAEKPKKKGFFSRLFSK*" gene 283003..283734 /gene="ycbR" /locus_tag="BSU_02610" /old_locus_tag="BSU02610" promotor_-10 complement(283205..283224) /Source="Nicolas_upshift_promotors" /id="U187" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.932067932067932" /psig="0.975024975024975" /xcortree=2967 /SigmaFactorBS="tatttaaaatttcacgatcgacatagcccgaaaaatcctttt ctgaAACTGGCTttaatcgggaaaaTTCATTATCATACACCCATAcatccagcaaacc g" /listShort="S98, ycbP" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(283231) /Source="Nicolas_upshifts" /id="U187" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.932067932067932" /psig="0.975024975024975" /xcortree=2967 /SigmaFactorBS="tatttaaaatttcacgatcgacatagcccgaaaaatcctttt ctgaAACTGGCTttaatcgggaaaaTTCATTATCATACACCCATAcatccagcaaacc g" /listShort="S98, ycbP" /GFF_Attribute="listLong" promotor_-35 complement(283238..283245) /Source="Nicolas_upshift_promotors" /id="U187" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.932067932067932" /psig="0.975024975024975" /xcortree=2967 /SigmaFactorBS="tatttaaaatttcacgatcgacatagcccgaaaaatcctttt ctgaAACTGGCTttaatcgggaaaaTTCATTATCATACACCCATAcatccagcaaacc g" /listShort="S98, ycbP" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 283652 /Source="Nicolas_upshifts" /id="D105" /incds=1 /nref=9 /ntot=148 /MaxReadThrough="1.70712" /MaxDrop="3.61288" /score="25.6672471" /energy="-14.1" /TU="NA" /idTUdmin="U186" /TUdmin=7 /isTUend="TRUE" CDS 283816..283992 /gene="yczK" /locus_tag="BSU_02619" /old_locus_tag="BSU02619" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="YP_003097673.1" /db_xref="EnsemblGenomes-Gn:BSU02619" /db_xref="EnsemblGenomes-Tr:CAX52543" /db_xref="UniProtKB/Swiss-Prot:C0H3T2" /translation="MGGLQTTGYAENASFSQLSACFSSRLVREDLFLMFSAYNQFTLL HSRLTMISYNGDDQ*" gene 283816..283992 /gene="yczK" /locus_tag="BSU_02619" /old_locus_tag="BSU02619" promotor_-35 283944..283950 /Source="Nicolas_upshift_promotors" /id="U188" /multdbtbs="SigA" /comp="M6" /sig="Sig-" /pcomp="0.942057942057942" /psig="0.056943056943057" /xcortree=6 /SigmaFactorBS="gtttttaatgttcagcgcttacaatcagttcacactTCTTCA CagtcgtTTAACAATGATTTCCTATaatggagacgatcaatgaggagagaggggatct t" /listShort="phoD, tatAD, S99, tatCD" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 283957..283974 /Source="Nicolas_upshift_promotors" /id="U188" /multdbtbs="SigA" /comp="M6" /sig="Sig-" /pcomp="0.942057942057942" /psig="0.056943056943057" /xcortree=6 /SigmaFactorBS="gtttttaatgttcagcgcttacaatcagttcacactTCTTCA CagtcgtTTAACAATGATTTCCTATaatggagacgatcaatgaggagagaggggatct t" /listShort="phoD, tatAD, S99, tatCD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 283968 /Source="Nicolas_upshifts" /id="U188" /multdbtbs="SigA" /comp="M6" /sig="Sig-" /pcomp="0.942057942057942" /psig="0.056943056943057" /xcortree=6 /SigmaFactorBS="gtttttaatgttcagcgcttacaatcagttcacactTCTTCA CagtcgtTTAACAATGATTTCCTATaatggagacgatcaatgaggagagaggggatct t" /listShort="phoD, tatAD, S99, tatCD" /GFF_Attribute="listLong" CDS 284011..285762 /gene="phoD" /locus_tag="BSU_02620" /old_locus_tag="BSU02620" /EC_number="3.1.4.46" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:11719524, 12867413, 16698798, 19395490, 19616508, 21479178, 27780866" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11719524, 12867413, 16698798, 19395490, 19616508, 21479178, 27780866; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="secreted phosphodiesterase (endo-hydrolysis at non-specific sites throughout the cell wall teichoic acid polymer)" /protein_id="NP_388144.2" /db_xref="EnsemblGenomes-Gn:BSU02620" /db_xref="EnsemblGenomes-Tr:CAB12056" /db_xref="GOA:P42251" /db_xref="InterPro:IPR008963" /db_xref="InterPro:IPR018946" /db_xref="InterPro:IPR029052" /db_xref="InterPro:IPR032093" /db_xref="PDB:2YEQ" /db_xref="SubtiList:BG11174" /db_xref="UniProtKB/Swiss-Prot:P42251" /translation="MAYDSRFDEWVQKLKEESFQNNTFDRRKFIQGAGKIAGLSLGLT IAQSVGAFEVNAAPNFSSYPFTLGVASGDPLSDSVVLWTRLAPDPLNGGGMPKQAVPV KWEVAKDEHFRKIVRKGTEMAKPSLAHSVHVEADGLEPNKVYYYRFKTGHELSPVGKT KTLPAPGANVPQMTFAFASCQQYEHGYYTAYKHMAKEKLDLVFHLGDYIYEYGPNEYV SKTGNVRTHNSAEIITLQDYRNRHAQYRSDANLKAAHAAFPWVVTWDDHEVENNYANK IPEKGQSVEAFVLRRAAAYQAYYEHMPLRISSLPNGPDMQLYRHFTYGNLASFNVLDT RQYRDDQANNDGNKPPSDESRNPNRTLLGKEQEQWLFNNLGSSTAHWNVLAQQIFFAK WNFGTSASPIYSMDSWDGYPAQRERVINFIKSKNLNNVVVLTGDVHASWASNLHVDFE KTSSKIFGAEFVGTSITSGGNGADKRADTDQILKENPHIQFFNDYRGYVRCTVTPHQW KADYRVMPFVTEPGAAISTRASFVYQKDQTGLRKVSSTTIQGGVKQSDEVEEDRFFSH NKAHEKQMIKKRAKITN*" gene 284011..285762 /gene="phoD" /locus_tag="BSU_02620" /old_locus_tag="BSU02620" promotor_-10 complement(284065..284080) /Source="Nicolas_upshift_promotors" /id="U189" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp="0.875124875124875" /psig="0.875124875124875" /xcortree=1703 /SigmaFactorBS="gagaaagtcctgcaatcttccccgctcctTGAATAAATTtgc ggcggtcaaACGTATTGTTTTGAAAgctttcctctttcagtttctgtacccattcatc a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(284071) /Source="Nicolas_upshifts" /id="U189" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp="0.875124875124875" /psig="0.875124875124875" /xcortree=1703 /SigmaFactorBS="gagaaagtcctgcaatcttccccgctcctTGAATAAATTtgc ggcggtcaaACGTATTGTTTTGAAAgctttcctctttcagtttctgtacccattcatc a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(284093..284102) /Source="Nicolas_upshift_promotors" /id="U189" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp="0.875124875124875" /psig="0.875124875124875" /xcortree=1703 /SigmaFactorBS="gagaaagtcctgcaatcttccccgctcctTGAATAAATTtgc ggcggtcaaACGTATTGTTTTGAAAgctttcctctttcagtttctgtacccattcatc a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" CDS 285775..285987 /gene="tatAD" /locus_tag="BSU_02630" /old_locus_tag="BSU02630" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:12867413, 15554971, 16678787, 19049517, 21479530, 27984091" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12867413, 15554971, 16678787, 19049517, 21479530, 27984091; Product type t : transporter" /codon_start=1 /transl_table=11 /product="component of the twin-arginine pre-protein translocation pathway" /protein_id="NP_388145.2" /db_xref="EnsemblGenomes-Gn:BSU02630" /db_xref="EnsemblGenomes-Tr:CAB12057" /db_xref="GOA:O31467" /db_xref="InterPro:IPR003369" /db_xref="InterPro:IPR003998" /db_xref="InterPro:IPR006312" /db_xref="PDB:2L16" /db_xref="SubtiList:BG12777" /db_xref="UniProtKB/Swiss-Prot:O31467" /translation="MFSNIGIPGLILIFVIALIIFGPSKLPEIGRAAGRTLLEFKSAT KSLVSGDEKEEKSAELTAVKQDKNAG*" gene 285775..285987 /gene="tatAD" /locus_tag="BSU_02630" /old_locus_tag="BSU02630" S_feature 285988..286047 /Source="Nicolas_S_feature" /locus_tag="new_285988_286047" /HighExp="LPhT, BI, Paraq, C90, H2O2, M40t90, C30, M0t90, GM 60, GM 120" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="Sig-" /TUshortPSig="0.0569" /TUlongSig="NA" /TUlongPSig="NA" /label="S99" CDS 286048..286776 /gene="tatCD" /locus_tag="BSU_02640" /old_locus_tag="BSU02640" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:16698798, 19049517, 27984091" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16698798, 19049517, 27984091; Product type t: transporter" /codon_start=1 /transl_table=11 /product="component of the twin-arginine pre-protein translocation pathway" /protein_id="NP_388146.2" /db_xref="EnsemblGenomes-Gn:BSU02640" /db_xref="EnsemblGenomes-Tr:CAB12058" /db_xref="GOA:P42252" /db_xref="InterPro:IPR002033" /db_xref="InterPro:IPR019820" /db_xref="SubtiList:BG11175" /db_xref="UniProtKB/Swiss-Prot:P42252" /translation="MDKKETHLIGHLEELRRRIIVTLAAFFLFLITAFLFVQDIYDWL IRDLDGKLAVLGPSEILWVYMMLSGICAIAASIPVAAYQLWRFVAPALTKTERKVTLM YIPGLFALFLAGISFGYFVLFPIVLSFLTHLSSGHFETMFTADRYFRFMVNLSLPFGF LFEMPLVVMFLTRLGILNPYRLAKARKLSYFLLIVVSILITPPDFISDFLVMIPLLVL FEVSVTLSAFVYKKRMREETAAAA*" gene 286048..286776 /gene="tatCD" /locus_tag="BSU_02640" /old_locus_tag="BSU02640" downshifts complement(286056) /Source="Nicolas_upshifts" /id="D106" /incds=0 /nref=4 /ntot=146 /MaxReadThrough="1.2763" /MaxDrop="3.13944" /score="-9.00478071" /energy="-8.5" /TU="NA" /idTUdmin="U190" /TUdmin="-6" /isTUend="TRUE" CDS complement(286773..287420) /gene="pcp" /locus_tag="BSU_02650" /old_locus_tag="BSU02650" /EC_number="3.4.19.3" /function="16.6: Maintain" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:1362573, 28830929" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1362573, 28830929; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="pyrrolidone-carboxylate (pyroglutamate) peptidase" /protein_id="NP_388147.1" /db_xref="EnsemblGenomes-Gn:BSU02650" /db_xref="EnsemblGenomes-Tr:CAB12059" /db_xref="GOA:P28618" /db_xref="InterPro:IPR000816" /db_xref="InterPro:IPR016125" /db_xref="InterPro:IPR029762" /db_xref="InterPro:IPR033693" /db_xref="InterPro:IPR033694" /db_xref="InterPro:IPR036440" /db_xref="SubtiList:BG10873" /db_xref="UniProtKB/Swiss-Prot:P28618" /translation="MRKKVLITGFDPFDKETVNPSWEAAKRLNGFETEEAIITAEQIP TVFRSALDTLRQAIQKHQPDIVICVGQAGGRMQITPERVAINLADARIPDNEGHQPID EEISPDGPAAYWTRLPVKRMTAKMKEHGIPAAVSYTAGTFVCNYLFYGLMDHISRTSP HIRGGFIHIPYIPQQTIDKTAPSLSLDTIVRALRIAAVTAAQYDEDVKSPGGTLH*" gene complement(286773..287420) /gene="pcp" /locus_tag="BSU_02650" /old_locus_tag="BSU02650" promotor_-10 complement(287435..287454) /Source="Nicolas_upshift_promotors" /id="U190" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.487512487512487" /psig="0.957042957042957" /xcortree=559 /SigmaFactorBS="aaatgctccattatgattcactcctttacattatttTGATGa aaaacccataaatAAACAATAGAATAAAAGAAAaaggagatgggagaatgagaaaaaa a" /listShort="pcp" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 287448..287454 /Source="Nicolas_upshift_promotors" /id="U191" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.603396603396603" /psig="0.988011988011988" /xcortree=2718 /SigmaFactorBS="tttttctcattctcccatctcctttttcttttattctATTGT TTatttatgggtttttCATCAAAATAATGTAAAGGAgtgaatcataatggagcatttg c" /listShort="ycbU" /GFF_Attribute="listLong" /label="promotor_-35" upshifts complement(287449) /Source="Nicolas_upshifts" /id="U190" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.487512487512487" /psig="0.957042957042957" /xcortree=559 /SigmaFactorBS="aaatgctccattatgattcactcctttacattatttTGATGa aaaacccataaatAAACAATAGAATAAAAGAAAaaggagatgggagaatgagaaaaaa a" /listShort="pcp" /GFF_Attribute="listLong" promotor_-10 287469..287488 /Source="Nicolas_upshift_promotors" /id="U191" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.603396603396603" /psig="0.988011988011988" /xcortree=2718 /SigmaFactorBS="tttttctcattctcccatctcctttttcttttattctATTGT TTatttatgggtttttCATCAAAATAATGTAAAGGAgtgaatcataatggagcatttg c" /listShort="ycbU" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 complement(287469..287473) /Source="Nicolas_upshift_promotors" /id="U190" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.487512487512487" /psig="0.957042957042957" /xcortree=559 /SigmaFactorBS="aaatgctccattatgattcactcctttacattatttTGATGa aaaacccataaatAAACAATAGAATAAAAGAAAaaggagatgggagaatgagaaaaaa a" /listShort="pcp" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 287471 /Source="Nicolas_upshifts" /id="U191" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.603396603396603" /psig="0.988011988011988" /xcortree=2718 /SigmaFactorBS="tttttctcattctcccatctcctttttcttttattctATTGT TTatttatgggtttttCATCAAAATAATGTAAAGGAgtgaatcataatggagcatttg c" /listShort="ycbU" /GFF_Attribute="listLong" CDS 287499..288611 /gene="ycbU" /locus_tag="BSU_02660" /old_locus_tag="BSU02660" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative lyase (PLP-dependent)" /protein_id="NP_388148.2" /db_xref="EnsemblGenomes-Gn:BSU02660" /db_xref="EnsemblGenomes-Tr:CAB12060" /db_xref="GOA:P42253" /db_xref="InterPro:IPR000192" /db_xref="InterPro:IPR015421" /db_xref="InterPro:IPR015422" /db_xref="InterPro:IPR015424" /db_xref="InterPro:IPR020578" /db_xref="SubtiList:BG11176" /db_xref="UniProtKB/Swiss-Prot:P42253" /translation="MEHLPEQYRQLFPTLQTHTMLASCSQSALAEPVSRAIQDYYDSL LYKGTNWKEAIEKTEFARNEFAKLIGAEPDEVAIVPSVSDALVSVASSLTAFGKKHVV YTDMDFPAVPHVWQAHSDYTVSVIPSIDGVLPLEQYETHISDETVLTCVPHVHYRDGY VQDIKAIAEISQRKGSLLFVDAYQSAGHIPIDVKEWGVDMLAAGTRKYLLGIPGVAFL YVRKELADALKPKASAWFGRESGFDGAYAKVARRFQTGTPAFISVYAAAAALSLLNHI GVSHIRDHVKTICADAVQYAAEKGLQLAAAQGGIQPGMVAIRDERASETAGLLKKKKV ICAPRENVIRLAPHFYNTKEEMRHAIDEIAAKTIHK*" gene 287499..288611 /gene="ycbU" /locus_tag="BSU_02660" /old_locus_tag="BSU02660" upshifts complement(287845) /Source="Nicolas_upshifts" /id="U192" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.954045954045954" /psig="0.999000999001" /xcortree=2851 /SigmaFactorBS="tcaagcggcagcacgccgTCTATtgatggaatgacggaTACG GTATAATCGGAGTGTGcctgccaaacatgaggcaccgccggaaaatccatatctgtat a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 complement(287848..287867) /Source="Nicolas_upshift_promotors" /id="U192" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.954045954045954" /psig="0.999000999001" /xcortree=2851 /SigmaFactorBS="tcaagcggcagcacgccgTCTATtgatggaatgacggaTACG GTATAATCGGAGTGTGcctgccaaacatgaggcaccgccggaaaatccatatctgtat a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 complement(287883..287887) /Source="Nicolas_upshift_promotors" /id="U192" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.954045954045954" /psig="0.999000999001" /xcortree=2851 /SigmaFactorBS="tcaagcggcagcacgccgTCTATtgatggaatgacggaTACG GTATAATCGGAGTGTGcctgccaaacatgaggcaccgccggaaaatccatatctgtat a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 288605 /Source="Nicolas_upshifts" /id="D107" /incds=0 /nref=45 /ntot=226 /MaxReadThrough="1.10091" /MaxDrop="4.52742" /score="6.75687898" /energy="-14" /TU="NA" /idTUdmin="U191" /TUdmin=814 /isTUend="FALSE" CDS complement(288653..290092) /gene="lmrB" /locus_tag="BSU_02670" /old_locus_tag="BSU02670" /function="16.1: Circulate" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:15317768, 15849754, 16850406, 17483215" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15317768, 15849754, 16850406, 17483215; Product type t: transporter" /codon_start=1 /transl_table=11 /product="flavonoid efflux transporter; drug-export protein" /protein_id="NP_388149.1" /db_xref="EnsemblGenomes-Gn:BSU02670" /db_xref="EnsemblGenomes-Tr:CAB12061" /db_xref="GOA:O35018" /db_xref="InterPro:IPR004638" /db_xref="InterPro:IPR011701" /db_xref="InterPro:IPR020846" /db_xref="InterPro:IPR036259" /db_xref="SubtiList:BG12613" /db_xref="UniProtKB/Swiss-Prot:O35018" /translation="MILETTAKASQQYKVMPIMISLLLAGFIGMFSETALNIALTDLM KELNITAATVQWLTTGYLLVLGILVPVSGLLLQWFTTRQLFTVSLIFSILGTFIAALA PSFSFLLAARIVQALGTGLLLPLMFNTILVIFPPHKRGAAMGTIGLVIMFAPAIGPTF SGLVLEHLNWHWIFWISLPFLVLALVFGIAYMQNVSETTKPKIDVLSIILSTIGFGGI VFGFSNAGEGSGGWSSPTVIVSLIVGVVGLILFSIRQLTMKQPMMNLRAFKYPMFILG VIMVFICMMVILSSMLLLPMYLQGGLVLTAFASGLVLLPGGILNGFMSPVTGRLFDKY GPKWLVIPGFVIVTVVLWFFSNVTTTSTAVLIIILHTCLMIGISMIMMPAQTNGLNQL PREFYPDGTAIMNTLQQMAGAIGTAVAVSIMAAGQHDYMSTVKNPADPAVIPQALTAG VQHAFVFAMIVAIIGLIGAFFMKRVKVDH*" gene complement(288653..290092) /gene="lmrB" /locus_tag="BSU_02670" /old_locus_tag="BSU02670" downshifts complement(288660) /Source="Nicolas_upshifts" /id="D108" /incds=0 /nref=162 /ntot=245 /MaxReadThrough="0.65833" /MaxDrop="6.75228" /score="18.3484535" /energy="-14" /TU="U193" /idTUdmin="U193" /TUdmin="-23" /isTUend="FALSE" CDS complement(290132..290698) /gene="lmrA" /locus_tag="BSU_02680" /old_locus_tag="BSU02680" /function="16.8: Protect" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:12718394, 15317768, 17483215" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12718394, 15317768, 17483215; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional repressor of lmrAB and yxaGH operons (flavonoid and antibiotic resistance)" /protein_id="NP_388150.1" /db_xref="EnsemblGenomes-Gn:BSU02680" /db_xref="EnsemblGenomes-Tr:CAB12062" /db_xref="GOA:O34619" /db_xref="InterPro:IPR001647" /db_xref="InterPro:IPR009057" /db_xref="InterPro:IPR036271" /db_xref="SubtiList:BG12612" /db_xref="UniProtKB/Swiss-Prot:O34619" /translation="MSYGDSREKILSAATRLFQLQGYYGTGLNQIIKESGAPKGSLYY HFPGGKEQLAIEAVNEMKEYIRQKIADCMEACTDPAEGIQAFLKELSCQFSCTEDIEG LPVGLLAAETSLKSEPLREACHEAYKEWASVYEEKLRQTGCSESRAKEASTVVNAMIE GGILLSLTAKNSTPLLHISSCIPDLLKR*" gene complement(290132..290698) /gene="lmrA" /locus_tag="BSU_02680" /old_locus_tag="BSU02680" promotor_-10 complement(290736..290755) /Source="Nicolas_upshift_promotors" /id="U193" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.986013986013986" /psig=1 /xcortree=2398 /SigmaFactorBS="cttctttttttgtcttttcatacaatgaattttTCTTGACAa ttgatgattgaatCAAGATAATAGACCAGTCACtatatttttgattgcaattcagtaa g" /listShort="lmrA, lmrB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(290750) /Source="Nicolas_upshifts" /id="U193" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.986013986013986" /psig=1 /xcortree=2398 /SigmaFactorBS="cttctttttttgtcttttcatacaatgaattttTCTTGACAa ttgatgattgaatCAAGATAATAGACCAGTCACtatatttttgattgcaattcagtaa g" /listShort="lmrA, lmrB" /GFF_Attribute="listLong" promotor_-35 complement(290770..290777) /Source="Nicolas_upshift_promotors" /id="U193" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.986013986013986" /psig=1 /xcortree=2398 /SigmaFactorBS="cttctttttttgtcttttcatacaatgaattttTCTTGACAa ttgatgattgaatCAAGATAATAGACCAGTCACtatatttttgattgcaattcagtaa g" /listShort="lmrA, lmrB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 290852..290858 /Source="Nicolas_upshift_promotors" /id="U194" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.368631368631369" /psig="0.652347652347652" /xcortree=316 /SigmaFactorBS="acaaaaaatactgagagaaaagctgactgatcTTTTGACtga atagataaaatgTACAATGATTAATCATCAtatggatgtaaggagagaaatagatgaa a" /listShort="ansZ" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 290874..290891 /Source="Nicolas_upshift_promotors" /id="U194" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.368631368631369" /psig="0.652347652347652" /xcortree=316 /SigmaFactorBS="acaaaaaatactgagagaaaagctgactgatcTTTTGACtga atagataaaatgTACAATGATTAATCATCAtatggatgtaaggagagaaatagatgaa a" /listShort="ansZ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 290880 /Source="Nicolas_upshifts" /id="U194" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.368631368631369" /psig="0.652347652347652" /xcortree=316 /SigmaFactorBS="acaaaaaatactgagagaaaagctgactgatcTTTTGACtga atagataaaatgTACAATGATTAATCATCAtatggatgtaaggagagaaatagatgaa a" /listShort="ansZ" /GFF_Attribute="listLong" CDS 290915..292042 /gene="ansZ" /locus_tag="BSU_02690" /old_locus_tag="BSU02690" /EC_number="3.5.1.1" /function="16.6: Maintain" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:11914346, 17686772" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11914346, 17686772; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="L-asparaginase 2 (putative lipoprotein)" /protein_id="NP_388151.1" /db_xref="EnsemblGenomes-Gn:BSU02690" /db_xref="EnsemblGenomes-Tr:CAB12063" /db_xref="GOA:O34482" /db_xref="InterPro:IPR004550" /db_xref="InterPro:IPR006034" /db_xref="InterPro:IPR020827" /db_xref="InterPro:IPR027473" /db_xref="InterPro:IPR027474" /db_xref="InterPro:IPR027475" /db_xref="InterPro:IPR036152" /db_xref="InterPro:IPR037152" /db_xref="SubtiList:BG12755" /db_xref="UniProtKB/Swiss-Prot:O34482" /translation="MKKQRMLVLFTALLFVFTGCSHSPETKESPKEKAQTQKVSSASA SEKKDLPNIRILATGGTIAGADQSKTSTTEYKAGVVGVESLIEAVPEMKDIANVSGEQ IVNVGSTNIDNKILLKLAKRINHLLASDDVDGIVVTHGTDTLEETAYFLNLTVKSDKP VVIVGSMRPSTAISADGPSNLYNAVKVAGAPEAKGKGTLVVLNDRIASARYVTKTNTT TTDTFKSEEMGFVGTIADDIYFNNEITRKHTKDTDFSVSNLDELPQVDIIYGYQNDGS YLFDAAVKAGAKGIVFAGSGNGSLSDAAEKGADSAVKKGVTVVRSTRTGNGVVTPNQD YAEKDLLASNSLNPQKARMLLMLALTKTNDPQKIQAYFNEY*" gene 290915..292042 /gene="ansZ" /locus_tag="BSU_02690" /old_locus_tag="BSU02690" downshifts 292015 /Source="Nicolas_upshifts" /id="D109" /incds=0 /nref=3 /ntot=26 /MaxReadThrough="1.70459" /MaxDrop="4.27333" /score="23.2201078" /energy="-7.6" /TU="NA" /idTUdmin="U194" /TUdmin=0 /isTUend="TRUE" promotor_-35 292139..292145 /Source="Nicolas_upshift_promotors" /id="U195" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.455544455544456" /psig=1 /xcortree=3077 /SigmaFactorBS="tctgaatcttaaaatttctttaaaaataagccaaaattacCC TTTACttaattaatttggTAACGTAATATAATTGGAGAatttgttacaaaaaaaggag g" /listShort="estA, S100, yccF" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 292159..292178 /Source="Nicolas_upshift_promotors" /id="U195" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.455544455544456" /psig=1 /xcortree=3077 /SigmaFactorBS="tctgaatcttaaaatttctttaaaaataagccaaaattacCC TTTACttaattaatttggTAACGTAATATAATTGGAGAatttgttacaaaaaaaggag g" /listShort="estA, S100, yccF" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 292159 /Source="Nicolas_upshifts" /id="U195" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.455544455544456" /psig=1 /xcortree=3077 /SigmaFactorBS="tctgaatcttaaaatttctttaaaaataagccaaaattacCC TTTACttaattaatttggTAACGTAATATAATTGGAGAatttgttacaaaaaaaggag g" /listShort="estA, S100, yccF" /GFF_Attribute="listLong" CDS 292205..292843 /gene="estA" /locus_tag="BSU_02700" /old_locus_tag="BSU02700" /EC_number="3.1.1.3" /function="16.11: Scavenge (Catabolism)" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:8396026, 15812018, 18053819, 11029590, 24827611, 28963005" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8396026, 15812018, 18053819, 11029590, 24827611, 28963005; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="secreted alkaliphilic lipase" /protein_id="NP_388152.1" /db_xref="EnsemblGenomes-Gn:BSU02700" /db_xref="EnsemblGenomes-Tr:CAB12064" /db_xref="GOA:P37957" /db_xref="InterPro:IPR002918" /db_xref="InterPro:IPR029058" /db_xref="PDB:1I6W" /db_xref="PDB:1ISP" /db_xref="PDB:1R4Z" /db_xref="PDB:1R50" /db_xref="PDB:1T2N" /db_xref="PDB:1T4M" /db_xref="PDB:2QXT" /db_xref="PDB:2QXU" /db_xref="PDB:3D2A" /db_xref="PDB:3D2B" /db_xref="PDB:3D2C" /db_xref="PDB:3QMM" /db_xref="PDB:3QZU" /db_xref="PDB:5CRI" /db_xref="PDB:5CT4" /db_xref="PDB:5CT5" /db_xref="PDB:5CT6" /db_xref="PDB:5CT8" /db_xref="PDB:5CT9" /db_xref="PDB:5CTA" /db_xref="PDB:5CUR" /db_xref="SubtiList:BG10679" /db_xref="UniProtKB/Swiss-Prot:P37957" /translation="MKFVKRRIIALVTILMLSVTSLFALQPSAKAAEHNPVVMVHGIG GASFNFAGIKSYLVSQGWSRDKLYAVDFWDKTGTNYNNGPVLSRFVQKVLDETGAKKV DIVAHSMGGANTLYYIKNLDGGNKVANVVTLGGANRLTTGKALPGTDPNQKILYTSIY SSADMIVMNYLSRLDGARNVQIHGVGHIGLLYSSQVNSLIKEGLNGGGQNTN*" gene 292205..292843 /gene="estA" /locus_tag="BSU_02700" /old_locus_tag="BSU02700" downshifts 292829 /Source="Nicolas_upshifts" /id="D110" /incds=0 /nref=15 /ntot=117 /MaxReadThrough="4.54554" /MaxDrop="4.10395" /score="23.2201078" /energy="-7.6" /TU="U195" /idTUdmin="U194" /TUdmin=814 /isTUend="FALSE" S_feature 292874..293464 /Source="Nicolas_S_feature" /locus_tag="new_292874_293464" /HighExp="M9-tran, GM 150, LoTm, MG 150, GM 120, aero, T-1.40H, M/G, S2, GM 90" /AntisenseName="yczC" /AntisenseCor="3.5651747957185502E-2" /AntisenseRegPval="-0.3" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S100" CDS complement(292881..293264) /gene="yczC" /locus_tag="BSU_02710" /old_locus_tag="BSU02710" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 15849754, 16850406; Product type m:membrane component" /codon_start=1 /transl_table=11 /product="putative integral membrane protein of unknown function" /protein_id="NP_388153.1" /db_xref="EnsemblGenomes-Gn:BSU02710" /db_xref="EnsemblGenomes-Tr:CAB12065" /db_xref="GOA:O31469" /db_xref="InterPro:IPR010432" /db_xref="SubtiList:BG12778" /db_xref="UniProtKB/Swiss-Prot:O31469" /translation="MELAGFMLRACALLLDVIIAAAVILAAGFTFGDGSAGVIIVAIL MLIVYPLLMPLTNWKGTLGKKIIGLQIVRDETYKKISFPQAIVRYLIAWVHVFSRLIY LTAAFTKKKQTVHDMAAKTIVLKAE*" gene complement(292881..293264) /gene="yczC" /locus_tag="BSU_02710" /old_locus_tag="BSU02710" downshifts complement(292905) /Source="Nicolas_upshifts" /id="D111" /incds=0 /nref=4 /ntot=94 /MaxReadThrough="0.85389" /MaxDrop="2.7858" /score="15.0330092" /energy="-12.1" /TU="NA" /idTUdmin="U196" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(293294..293313) /Source="Nicolas_upshift_promotors" /id="U196" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.507492507492508" /psig="0.835164835164835" /xcortree=3082 /SigmaFactorBS="aacttttgtgatttaaggcttatcaccTATTCCCActttagg cccttcTTTTTTACAATCATTAGGTGtttatttaacattttaaggagtgtttctattg g" /listShort="yczC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(293301) /Source="Nicolas_upshifts" /id="U196" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.507492507492508" /psig="0.835164835164835" /xcortree=3082 /SigmaFactorBS="aacttttgtgatttaaggcttatcaccTATTCCCActttagg cccttcTTTTTTACAATCATTAGGTGtttatttaacattttaaggagtgtttctattg g" /listShort="yczC" /GFF_Attribute="listLong" promotor_-35 complement(293327..293334) /Source="Nicolas_upshift_promotors" /id="U196" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.507492507492508" /psig="0.835164835164835" /xcortree=3082 /SigmaFactorBS="aacttttgtgatttaaggcttatcaccTATTCCCActttagg cccttcTTTTTTACAATCATTAGGTGtttatttaacattttaaggagtgtttctattg g" /listShort="yczC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 293436..293439 /Source="Nicolas_upshift_promotors" /id="U197" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.916083916083916" /psig="0.999000999001" /xcortree=2575 /SigmaFactorBS="acattaccaaattcttttttagcccgaaacCAAGccctcaga agttattTTTGTTAAAATAGAAAAGTTacaacagaattcggagggtttattgtgggaa a" /listShort="yccF" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 293455..293474 /Source="Nicolas_upshift_promotors" /id="U197" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.916083916083916" /psig="0.999000999001" /xcortree=2575 /SigmaFactorBS="acattaccaaattcttttttagcccgaaacCAAGccctcaga agttattTTTGTTAAAATAGAAAAGTTacaacagaattcggagggtttattgtgggaa a" /listShort="yccF" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 293466 /Source="Nicolas_upshifts" /id="U197" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.916083916083916" /psig="0.999000999001" /xcortree=2575 /SigmaFactorBS="acattaccaaattcttttttagcccgaaacCAAGccctcaga agttattTTTGTTAAAATAGAAAAGTTacaacagaattcggagggtttattgtgggaa a" /listShort="yccF" /GFF_Attribute="listLong" CDS 293499..294575 /gene="yccF" /locus_tag="BSU_02720" /old_locus_tag="BSU02720" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_388154.1" /db_xref="EnsemblGenomes-Gn:BSU02720" /db_xref="EnsemblGenomes-Tr:CAB12066" /db_xref="GOA:O34478" /db_xref="InterPro:IPR004027" /db_xref="InterPro:IPR007889" /db_xref="InterPro:IPR036915" /db_xref="SubtiList:BG12756" /db_xref="UniProtKB/Swiss-Prot:O34478" /translation="MGKVKRNAPCPCGSGKKYKKCCGSKVVDFPAELAAKEAKQIQED LVEYAFTVHRESISGFINQHDFLSAMDRQTKDISVFNLGIWGIFFHPLAGEKTIFEEY LQKKGDSITRPKTREIVESWQSMTPALLLLKDLKEGIIHFEDVITAKQFEVEMDASNQ DLPPVGSLILGYPIHEAEKAEFFMQFTIFPVKRTEALISKVKKYADAAVKDGKTPEDF MKQEFNNVLFALLAEKDEEPQAEKAEVSTVEWANDLEKETAAAIEEGMSGEEYPTELI PAVIDIWKTFCEKKSPVIRKPEAFAAAVEYYVNAISLNGASVSQAKLAKKYGVSASTI SSRYKEIESTLQDEADRFAQALSS*" gene 293499..294575 /gene="yccF" /locus_tag="BSU_02720" /old_locus_tag="BSU02720" downshifts 294569 /Source="Nicolas_upshifts" /id="D112" /incds=0 /nref=60 /ntot=248 /MaxReadThrough="1.55048" /MaxDrop="5.18328" /score="33.0000484" /energy="-12.9" /TU="NA" /idTUdmin="U197" /TUdmin=2 /isTUend="TRUE" CDS complement(294615..295571) /gene="natK" /locus_tag="BSU_02730" /old_locus_tag="BSU02730" /function="16.3: Control" /function="16.12: Sense" /experiment="publication(s) with functional evidences, PMID:11717295, 17322186" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11717295, 17322186; Product type rc: receptor" /codon_start=1 /transl_table=11 /product="two-component sensor histidine kinase [NatR]" /protein_id="NP_388155.1" /db_xref="EnsemblGenomes-Gn:BSU02730" /db_xref="EnsemblGenomes-Tr:CAB12067" /db_xref="GOA:P70954" /db_xref="InterPro:IPR003594" /db_xref="InterPro:IPR032834" /db_xref="InterPro:IPR036890" /db_xref="SubtiList:BG11997" /db_xref="UniProtKB/Swiss-Prot:P70954" /translation="MITLFQCLYLILFSFICYQGAAAFSHSTAASWLAAALGAAAAGL YIWNTKRVWKHCSSGLCAWIAVIQVMSVGVVLIGTDIMPVLCVIAIFAGCEGLRIGQS ALQARLSDQIDKLTQAEQHANQMLIDVRSRNHDTMKHITAIKSAQPKADTQAYIQNWA DQYSQYDRFLKGENAYVAGVLYDFLEKARASNVSVSLHMHTPLSSLPFSPADQVSLVG NILENALDSAAEAREKAEIKLETSLRSGLYVLTCENSTPGMDPKVLDTIYQSFGRSTK NGAHEGMGTYIIQKLVKGAFGRLDFTYRHPIFRLEIKIPFQK*" gene complement(294615..295571) /gene="natK" /locus_tag="BSU_02730" /old_locus_tag="BSU02730" downshifts complement(294643) /Source="Nicolas_upshifts" /id="D113" /incds=0 /nref=1 /ntot=129 /MaxReadThrough="0.86926" /MaxDrop="2.67125" /score="14.02819" /energy="-12.9" /TU="NA" /idTUdmin="U198" /TUdmin=176 /isTUend="FALSE" CDS complement(295584..296285) /gene="natR" /locus_tag="BSU_02740" /old_locus_tag="BSU02740" /function="16.8: Protect" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:11717295, 17322186" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11717295, 17322186; Product type r: regulator" /codon_start=1 /transl_table=11 /product="two-component response regulator [NatK]" /protein_id="NP_388156.1" /db_xref="EnsemblGenomes-Gn:BSU02740" /db_xref="EnsemblGenomes-Tr:CAB12068" /db_xref="GOA:P70955" /db_xref="InterPro:IPR001789" /db_xref="InterPro:IPR007492" /db_xref="InterPro:IPR011006" /db_xref="SubtiList:BG11998" /db_xref="UniProtKB/Swiss-Prot:P70955" /translation="MVKVGLVDDYRVDLEKLEAIVSRMQDVEIVFSTDSAKEAYRRVK NGDIDLLLADIEMPHMSGYELADLIKSHSLDVDVIFVTGHGGYAVHAFDLNVHDYIMK PYYADRLAASFDRYLKKKTETSLNGRILIKQKSEMHVLQKKDIIFAERTGRSTTIVTT AEEVQTYQTLNDIKGDLPEKDFLRSHRSFIINIHYIKHFSAYTKHSFTVSFEGTSKKA MITKQQLDYFQNYYF*" gene complement(295584..296285) /gene="natR" /locus_tag="BSU_02740" /old_locus_tag="BSU02740" promotor_-10 complement(296309..296328) /Source="Nicolas_upshift_promotors" /id="U198" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.397602397602398" /psig="0.992007992007992" /xcortree=2173 /SigmaFactorBS="attagttggataaagttgtcgcgaagagTTCTttttatgtcg tgaaaTGGGATAGAATAAAGATGATtctatgtaactaggggaatgataatggtaaaag t" /listShort="natR, natK" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(296315) /Source="Nicolas_upshifts" /id="U198" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.397602397602398" /psig="0.992007992007992" /xcortree=2173 /SigmaFactorBS="attagttggataaagttgtcgcgaagagTTCTttttatgtcg tgaaaTGGGATAGAATAAAGATGATtctatgtaactaggggaatgataatggtaaaag t" /listShort="natR, natK" /GFF_Attribute="listLong" promotor_-35 complement(296344..296347) /Source="Nicolas_upshift_promotors" /id="U198" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.397602397602398" /psig="0.992007992007992" /xcortree=2173 /SigmaFactorBS="attagttggataaagttgtcgcgaagagTTCTttttatgtcg tgaaaTGGGATAGAATAAAGATGATtctatgtaactaggggaatgataatggtaaaag t" /listShort="natR, natK" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 296365..296368 /Source="Nicolas_upshift_promotors" /id="U199" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.356643356643357" /psig="0.844155844155844" /xcortree=1785 /SigmaFactorBS="cgacataaaaagaactcttcgcgacaactttATCCaactaat ccagctttTCGTATATAGTCATTACTAGaaataaagataagggagattgtgacatgat t" /listShort="natA, natB, yccK" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 296384..296403 /Source="Nicolas_upshift_promotors" /id="U199" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.356643356643357" /psig="0.844155844155844" /xcortree=1785 /SigmaFactorBS="cgacataaaaagaactcttcgcgacaactttATCCaactaat ccagctttTCGTATATAGTCATTACTAGaaataaagataagggagattgtgacatgat t" /listShort="natA, natB, yccK" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 296394 /Source="Nicolas_upshifts" /id="U199" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.356643356643357" /psig="0.844155844155844" /xcortree=1785 /SigmaFactorBS="cgacataaaaagaactcttcgcgacaactttATCCaactaat ccagctttTCGTATATAGTCATTACTAGaaataaagataagggagattgtgacatgat t" /listShort="natA, natB, yccK" /GFF_Attribute="listLong" CDS 296429..297169 /gene="natA" /locus_tag="BSU_02750" /old_locus_tag="BSU02750" /function="16.1: Circulate" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:10356997, 17322186" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10356997, 17322186; Product type t: transporter" /codon_start=1 /transl_table=11 /product="Na+ ABC efflux transporter (ATP-binding protein)" /protein_id="NP_388157.1" /db_xref="EnsemblGenomes-Gn:BSU02750" /db_xref="EnsemblGenomes-Tr:CAB12069" /db_xref="GOA:P46903" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR017871" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG11338" /db_xref="UniProtKB/Swiss-Prot:P46903" /translation="MITLTDCSRRFQDKKKVVKAVRDVSLTIEKGEVVGILGENGAGK TTMLRMIASLLEPSQGVITVDGFDTVKQPAEVKQRIGVLFGGETGLYDRMTAKENLQY FGRLYGLNRHEIKARIEDLSKRFGMRDYMNRRVGGFSKGMRQKVAIARALIHDPDIIL FDEPTTGLDITSSNIFREFIQQLKREQKTILFSSHIMEEVQALCDSVIMIHSGEVIYR GALESLYESERSEDLNYIFMSKLVRGIS*" gene 296429..297169 /gene="natA" /locus_tag="BSU_02750" /old_locus_tag="BSU02750" CDS 297170..298330 /gene="natB" /locus_tag="BSU_02760" /old_locus_tag="BSU02760" /function="16.8: Protect" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:10356997, 15849754, 16850406, 17322186" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10356997, 15849754, 16850406, 17322186; Product type t: transporter" /codon_start=1 /transl_table=11 /product="Na+ ABC efflux transporter (permease)" /protein_id="NP_388158.1" /db_xref="EnsemblGenomes-Gn:BSU02760" /db_xref="EnsemblGenomes-Tr:CAB12070" /db_xref="GOA:P46904" /db_xref="InterPro:IPR032688" /db_xref="SubtiList:BG11339" /db_xref="UniProtKB/Swiss-Prot:P46904" /translation="MLSHIYKKEMIDALRDRKTILLTILVPMIMMLGLVFFYESMLSD KGEQYTLAVGHSLPPALESKLNEIDEISVKTFAKPEEAVDEGKADAYLNVPKEFDSYV NSMTPFKVDVYGNSIDQGSSNAMQLVQSALDQYKNEIVQQRLTNKHIDQSVIQPFTIQ QKEADEEKGTSAIMLSAILPMLILTSIVSGAMPIALDIMAGEKDRKSIEALLLTPVSR NKVLVGKWLAVSTFGVASGVFALVFLILSTVLFTENLKTAFQLGDHMWSVIGASALII VLSALLISAMELFISIMSSSVKEAQSYMSLVVFLPVFPMFFIFSKAPNQFDLSYFLIP FLNLHALFKQLLFGMVDPATILSTSGTIAVLIAIFFLLARACFLKDKWVLPK*" gene 297170..298330 /gene="natB" /locus_tag="BSU_02760" /old_locus_tag="BSU02760" promotor_-35 298381..298389 /Source="Nicolas_upshift_promotors" /id="U200" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp=1 /psig=1 /xcortree=430 /SigmaFactorBS="ggagaaatacactttctcctttttgtatatcctgaaaaaaGA AGGAAAAtagaaaaaggaTATCTAATACAAAAAGTGAccctgcactatttttcatcaa a" /listShort="yccK" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 298401..298419 /Source="Nicolas_upshift_promotors" /id="U200" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp=1 /psig=1 /xcortree=430 /SigmaFactorBS="ggagaaatacactttctcctttttgtatatcctgaaaaaaGA AGGAAAAtagaaaaaggaTATCTAATACAAAAAGTGAccctgcactatttttcatcaa a" /listShort="yccK" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 298401 /Source="Nicolas_upshifts" /id="U200" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp=1 /psig=1 /xcortree=430 /SigmaFactorBS="ggagaaatacactttctcctttttgtatatcctgaaaaaaGA AGGAAAAtagaaaaaggaTATCTAATACAAAAAGTGAccctgcactatttttcatcaa a" /listShort="yccK" /GFF_Attribute="listLong" CDS 298466..299398 /gene="yccK" /locus_tag="BSU_02770" /old_locus_tag="BSU02770" /EC_number="1.-.-.-" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 17322186, 24330391; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative ion channel associated aldo-keto reductase" /protein_id="NP_388159.1" /db_xref="EnsemblGenomes-Gn:BSU02770" /db_xref="EnsemblGenomes-Tr:CAB12071" /db_xref="GOA:P46905" /db_xref="InterPro:IPR020471" /db_xref="InterPro:IPR023210" /db_xref="InterPro:IPR036812" /db_xref="SubtiList:BG11340" /db_xref="UniProtKB/Swiss-Prot:P46905" /translation="MDQTRTLGKTKLKVKRIGFGANAVGGHNLFPNLNDETGKDLVRT ALDGGVNFIDTAFIYGLGRSEELIGEVVQERGVRNELIIATKGAHKEVDGSIELDNSR EFLRSEVEKSLKRLKTDYIDLYYVHFPDGKTPLAEVAGTLKELKDEGKIKAIGASNLD YQQLQDFNADGYLEVFQAEYSLIQRDAEKELLPYCEKQGISFIPYFPLASGLLTGKFT QDTVFDDFRKDKPQFQGETFIHNLKKVDKLKAVAEEKQADTAHVALAWLLTRPAIDAI IPGAKRPEQLQDNLKTLNIELTEDEVNFISDIFK*" gene 298466..299398 /gene="yccK" /locus_tag="BSU_02770" /old_locus_tag="BSU02770" CDS complement(299438..300502) /gene="ycdA" /locus_tag="BSU_02780" /old_locus_tag="BSU02780" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1b: Function from experimental evidences in the studied species; PubMedId: 22496484; Product type lp: lipoprotein" /codon_start=1 /transl_table=11 /product="lipoprotein involved in swarming behaviour" /protein_id="NP_388160.1" /db_xref="EnsemblGenomes-Gn:BSU02780" /db_xref="EnsemblGenomes-Tr:CAB12072" /db_xref="GOA:O34538" /db_xref="InterPro:IPR029050" /db_xref="InterPro:IPR029051" /db_xref="InterPro:IPR031343" /db_xref="PDB:4R4G" /db_xref="SubtiList:BG12757" /db_xref="UniProtKB/Swiss-Prot:O34538" /translation="MFQKKTYAVFLILLLMMFTAACSGSKTSAEKKESETEKSSDIAQ VKIKDVSYTLPSKYDKSTSDDQLVLKVNVAVKNTGKDPLNVDSMDFTLYQGDTKMSDT DPEDYSEKLQGSTINADKSVEGNLFFVVDKGKQYELNYTPESYGDKKPKSVTFKIDGK DKKILATADKLQDSAKALSAYVDVLLFGKDNADFEKITGANKNEIVNDFNESAKDGYL SASGLSSTYADSKALDNIVNGIKEGLSKNSSIQAKTTSISKDEAIVEATVKPVDASSL SDRIEDKVKDYYSKNSSASYEEAVKYALQVYPEEFKKLGPASSEKTVEVKMKKNDIDQ WQLDMDDYRAAELVEAFIKE*" gene complement(299438..300502) /gene="ycdA" /locus_tag="BSU_02780" /old_locus_tag="BSU02780" downshifts complement(299439) /Source="Nicolas_upshifts" /id="D114" /incds=0 /nref=198 /ntot=222 /MaxReadThrough="0.57029" /MaxDrop="8.85093" /score="27.0612397" /energy="-13.7" /TU="NA" /idTUdmin="U201" /TUdmin=0 /isTUend="TRUE" S_feature complement(300503..300693) /Source="Nicolas_S_feature" /locus_tag="new_300503_300693_c" /HighExp="S5, S4, MG 45, MG 15, MG-0.2, MG 25, MG-0.1, MG 10, S3, MG t5" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.997" /TUlongSig="NA" /TUlongPSig="NA" /label="S101" CDS complement(300525..300656) /locus_tag="BSU_02785" /old_locus_tag="BSU02785" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_009513941.1" /translation="MTKEGGVSRKSGENREKRTDFFGYMMLIHSKRSISQRQKTPLS* " gene complement(300525..300656) /locus_tag="BSU_02785" /old_locus_tag="BSU02785" promotor_-10 complement(300678..300697) /Source="Nicolas_upshift_promotors" /id="U201" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.954045954045954" /psig="0.997002997002997" /xcortree=2915 /SigmaFactorBS="ttaccagaacatttttcaccaaaaataggatgatgaaccTAT TCAATataaaagctaataaTCTTAAAATTAATTCCGTTGtaactttttataggtccat t" /listShort="S101, ycdA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(300698) /Source="Nicolas_upshifts" /id="U201" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.954045954045954" /psig="0.997002997002997" /xcortree=2915 /SigmaFactorBS="ttaccagaacatttttcaccaaaaataggatgatgaaccTAT TCAATataaaagctaataaTCTTAAAATTAATTCCGTTGtaactttttataggtccat t" /listShort="S101, ycdA" /GFF_Attribute="listLong" promotor_-35 complement(300712..300719) /Source="Nicolas_upshift_promotors" /id="U201" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.954045954045954" /psig="0.997002997002997" /xcortree=2915 /SigmaFactorBS="ttaccagaacatttttcaccaaaaataggatgatgaaccTAT TCAATataaaagctaataaTCTTAAAATTAATTCCGTTGtaactttttataggtccat t" /listShort="S101, ycdA" /GFF_Attribute="listLong" /label="promotor_-35" CDS 300830..302248 /gene="ycdB" /locus_tag="BSU_02790" /old_locus_tag="BSU02790" /function="16.11: Scavenge (Catabolism)" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_388161.1" /db_xref="EnsemblGenomes-Gn:BSU02790" /db_xref="EnsemblGenomes-Tr:CAB12073" /db_xref="InterPro:IPR032599" /db_xref="SubtiList:BG12758" /db_xref="UniProtKB/Swiss-Prot:O34621" /translation="MKGAAFVKKEGLKQKALEIGRVPTHLKLEIEDYGGDDKRAHFCW ADPQDENTGIIVELGPDGELESLSRDIEPESGERLSEEKLEDIMRQFVETHHPGALSA FVREENDRAYGDKVRFSYVQMEAGLPLPMSGFMADVSLSGEIVYFRYYGEAGSIIKPK RVADVEEALAFIKKDVEFDLLFEVLHRSVYKNGDDQPHLVYEPEGRAITVPADLVQEE QAVDDDDDYREPESFPLPLFEGIREKADPDSMIGIENGFVKEREADLGDGRIGIVWRN PDDPVYQPADKSMDSWFKGRTHQVLKTIYNKETGKLEGVMSFMEKKGPLTVTLAECEK IALRFLFALFPNADQYFRIRYDEKDEEENAVAGFTFEAHCHGVPLRFGQIRICVSRQT GYITVYMGPDIDPNKLATIDPVPAISVEQAKSIFWQHFKVELGWEREYGDDEEHSYRL VYKPVYPHFIDAHTGEPVFSIW*" gene 300830..302248 /gene="ycdB" /locus_tag="BSU_02790" /old_locus_tag="BSU02790" promotor_-10 complement(302291..302309) /Source="Nicolas_upshift_promotors" /id="U202" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.685314685314685" /psig="0.96903096903097" /xcortree=2432 /SigmaFactorBS="agtgaagaaaggtccttttctattattgtCATTGTTTtttga gattctttCTGTTACTTTCATCACATActctcttctatatctgaggcaattgcgtgac t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(302299) /Source="Nicolas_upshifts" /id="U202" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.685314685314685" /psig="0.96903096903097" /xcortree=2432 /SigmaFactorBS="agtgaagaaaggtccttttctattattgtCATTGTTTtttga gattctttCTGTTACTTTCATCACATActctcttctatatctgaggcaattgcgtgac t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(302323..302330) /Source="Nicolas_upshift_promotors" /id="U202" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.685314685314685" /psig="0.96903096903097" /xcortree=2432 /SigmaFactorBS="agtgaagaaaggtccttttctattattgtCATTGTTTtttga gattctttCTGTTACTTTCATCACATActctcttctatatctgaggcaattgcgtgac t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" S_feature 302355..302434 /Source="Nicolas_S_feature" /locus_tag="new_302355_302434" /HighExp="ferm, M40t45, M0t45, Lbstat, S0, nit, LBGtran, Lbtran, G135, LBGstat" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.868" /TUlongSig="NA" /TUlongPSig="NA" /label="S102" upshifts 302355 /Source="Nicolas_upshifts" /id="U203" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.48051948051948" /psig="0.868131868131868" /xcortree=1586 /SigmaFactorBS="tgatgaaagtaacagaaagaatctcaaaaaacaatgacaata atagaaaaggacctttcttcACTTTAAatgaagaaaggtctTTTTATATAATAAACAG G" /listShort="S102, ycdC, S103" /listLong="rapJ" promotor_-35 302357..302363 /Source="Nicolas_upshift_promotors" /id="U203" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.48051948051948" /psig="0.868131868131868" /xcortree=1586 /SigmaFactorBS="tgatgaaagtaacagaaagaatctcaaaaaacaatgacaata atagaaaaggacctttcttcACTTTAAatgaagaaaggtctTTTTATATAATAAACAG G" /listShort="S102, ycdC, S103" /listLong="rapJ" /label="promotor_-35" promotor_-10 302378..302395 /Source="Nicolas_upshift_promotors" /id="U203" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.48051948051948" /psig="0.868131868131868" /xcortree=1586 /SigmaFactorBS="tgatgaaagtaacagaaagaatctcaaaaaacaatgacaata atagaaaaggacctttcttcACTTTAAatgaagaaaggtctTTTTATATAATAAACAG G" /listShort="S102, ycdC, S103" /listLong="rapJ" /label="promotor_-10" CDS 302435..303796 /gene="ycdC" /locus_tag="BSU_02800" /old_locus_tag="BSU02800" /function="16.11: Scavenge (Catabolism)" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_388162.1" /db_xref="EnsemblGenomes-Gn:BSU02800" /db_xref="EnsemblGenomes-Tr:CAB12074" /db_xref="InterPro:IPR032599" /db_xref="SubtiList:BG12759" /db_xref="UniProtKB/Swiss-Prot:O34772" /translation="MVNKQLKKKAQEIGNVPTHYELEIEDYDQKQKKYGQAYFIWKDP KDPEKHITVELRNDGALLTFSTTVHSETDKKLPDAELKLTALQFAAANHPGTFMNFHF QGKEERGQHIRFVYTKMELGLPIPNSGFLIDMTRSGQIVHFLYYGEGHKAEVPTEFVA KEKVVSHYLNTMSFELMYDVIDGEQEPRLVYEPILPGYSYPADVDEIVPDQHIADERI ENTAPLPPLQNKEEVDIFALLGFTSDMQKVSERDFGEQIGSTWRRGAAPERKDLSIGS YFETRNKNTIKMKTDKRTGKLKAALSFMDWRNNLQCSTEECQEIALQFLYALYPRAAE FFRVNPVRIDERGRVRNHFSVWYKGVPLRFGAARIIVNPETGLIDAFMAPDIEPEQLE AINHRPDVSAEEAKEAFLAAFDVKLEWQPDFTAGSDQHCKLVYKPVYPSYIDAHIRKK KRL*" gene 302435..303796 /gene="ycdC" /locus_tag="BSU_02800" /old_locus_tag="BSU02800" S_feature 303797..304377 /Source="Nicolas_S_feature" /locus_tag="new_303797_304377" /HighExp="ferm, M0t45, G135, G180, H2O2, M40t45, G150, Paraq, S0, nit" /AntisenseName="cwlK" /AntisenseCor="0.27553388443794402" /AntisenseRegPval="-5.3" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.868" /TUlongSig="NA" /TUlongPSig="NA" /label="S103" CDS complement(303804..304307) /gene="cwlK" /locus_tag="BSU_02810" /old_locus_tag="BSU02810" /EC_number="3.4.-.-" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:17588176" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 17588176; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="murein L,D:-endopeptidase" /protein_id="NP_388163.1" /db_xref="EnsemblGenomes-Gn:BSU02810" /db_xref="EnsemblGenomes-Tr:CAB12075" /db_xref="GOA:O34360" /db_xref="InterPro:IPR009045" /db_xref="SubtiList:BG12760" /db_xref="UniProtKB/Swiss-Prot:O34360" /translation="MNLPAKTFVILCILFLLDLCFSYIRHEWHSQNALQDMPVPSDLH PIVKQNADALKAAAANKGIDVVITEGFRSFKEQDELYKQGRTKKGNIVTYARGGESYH NYGLAIDFALQKKDGSIIWDMEYDGNQNGKSDWLEVVEIAKTLGFEWGGDWKRFKDYP HLEMIPN*" gene complement(303804..304307) /gene="cwlK" /locus_tag="BSU_02810" /old_locus_tag="BSU02810" S_feature complement(304308..304389) /Source="Nicolas_S_feature" /locus_tag="new_304308_304389_c" /HighExp="Cold, T0.30H, LBGstat, C30, T-0.40H, T1.0H, T1.30H, H2O2, T0.0H, T-1.10H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.946" /TUlongSig="NA" /TUlongPSig="NA" /label="S104" upshifts 304379 /Source="Nicolas_upshifts" /id="U204" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.992007992007992" /psig=1 /xcortree=2275 /SigmaFactorBS="tttctcaagatgtgctgaatgttaacgcttttaagtgattga ctctctctaaaagcgaacagcTATGATAAAATATAACATAAatagtagcaggaggaag g" /listShort="rapJ" /listLong="ycdF, ycdG, adcA, adcC, adcB" promotor_-10 complement(304381..304400) /Source="Nicolas_upshift_promotors" /id="U205" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.576423576423576" /psig="0.946053946053946" /xcortree=2433 /SigmaFactorBS="tgatggaatctttgctctcatcggtctgcctccttccTcctg ctactattTATGTTATATTTTATCATAGctgttcgcttttagagagagtcaatcactt a" /listShort="S104, cwlK" /GFF_Attribute="listLong" /label="promotor_-10" misc_feature 304382..304401 /Source="Nicolas_upshift_promotors" /id="U204" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.992007992007992" /psig=1 /xcortree=2275 /SigmaFactorBS="tttctcaagatgtgctgaatgttaacgcttttaagtgattga ctctctctaaaagcgaacagcTATGATAAAATATAACATAAatagtagcaggaggaag g" /listShort="rapJ" /listLong="ycdF, ycdG, adcA, adcC, adcB" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(304390) /Source="Nicolas_upshifts" /id="U205" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.576423576423576" /psig="0.946053946053946" /xcortree=2433 /SigmaFactorBS="tgatggaatctttgctctcatcggtctgcctccttccTcctg ctactattTATGTTATATTTTATCATAGctgttcgcttttagagagagtcaatcactt a" /listShort="S104, cwlK" /GFF_Attribute="listLong" promotor_-35 complement(304413) /Source="Nicolas_upshift_promotors" /id="U205" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.576423576423576" /psig="0.946053946053946" /xcortree=2433 /SigmaFactorBS="tgatggaatctttgctctcatcggtctgcctccttccTcctg ctactattTATGTTATATTTTATCATAGctgttcgcttttagagagagtcaatcactt a" /listShort="S104, cwlK" /GFF_Attribute="listLong" /label="promotor_-35" CDS 304430..305551 /gene="rapJ" /locus_tag="BSU_02820" /old_locus_tag="BSU02820" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:16816200" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16816200; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="response regulator aspartate phosphatase" /protein_id="NP_388164.1" /db_xref="EnsemblGenomes-Gn:BSU02820" /db_xref="EnsemblGenomes-Tr:CAB12076" /db_xref="GOA:O34327" /db_xref="InterPro:IPR011990" /db_xref="InterPro:IPR013026" /db_xref="InterPro:IPR019734" /db_xref="PDB:4GYO" /db_xref="SubtiList:BG12663" /db_xref="UniProtKB/Swiss-Prot:O34327" /translation="MRAKIPSEEVAVKLNEWYKLIRAFEADQAEALKQEIEYDLEDME ENQDLLLYFSLMEFRHRIMLDKLMPVKDSDTKPPFSDMLNEIESNQQKLTGLLEYYFY YFRGMYEFKQKNFILAIDHYKHAEEKLEYVEDEIEKAEFLFKVAEVYYHIKQTYFSMN YASQALDIYTKYELYGRRRVQCEFIIAGNLTDVYHHEKALTHLCSALEHARQLEEAYM IAAAYYNVGHCKYSLGDYKEAEGYFKTAAAIFEEHNFQQAVQAVFSLTHIYCKEGKYD KAVEAYDRGIKSAAEWEDDMYLTKFRLIHELYLGSGDLNVLTECFDLLESRQLLADAE DLLHDTAERFNQLEHYESAAFFYRRLMNIKKKLAEQRFQ*" gene 304430..305551 /gene="rapJ" /locus_tag="BSU_02820" /old_locus_tag="BSU02820" downshifts 305545 /Source="Nicolas_upshifts" /id="D115" /incds=0 /nref=88 /ntot=228 /MaxReadThrough="3.8438" /MaxDrop="5.06867" /score="32.2653577" /energy="-13.2" /TU="U204" /idTUdmin="U204" /TUdmin="-66" /isTUend="FALSE" promotor_-35 305592..305598 /Source="Nicolas_upshift_promotors" /id="U206" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=187 /SigmaFactorBS="tggcagagaactacaggttctctgctttttttgtgcTGTTTT CaactcggaaaaacaGGGTATTTTCCACTGCATAgtgagaaacagaggaggatatcaa g" /listShort="ycdF, ycdG, adcA, adcC, adcB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 305613..305631 /Source="Nicolas_upshift_promotors" /id="U206" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=187 /SigmaFactorBS="tggcagagaactacaggttctctgctttttttgtgcTGTTTT CaactcggaaaaacaGGGTATTTTCCACTGCATAgtgagaaacagaggaggatatcaa g" /listShort="ycdF, ycdG, adcA, adcC, adcB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 305616 /Source="Nicolas_upshifts" /id="U206" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=187 /SigmaFactorBS="tggcagagaactacaggttctctgctttttttgtgcTGTTTT CaactcggaaaaacaGGGTATTTTCCACTGCATAgtgagaaacagaggaggatatcaa g" /listShort="ycdF, ycdG, adcA, adcC, adcB" /GFF_Attribute="listLong" CDS 305658..306434 /gene="ycdF" /locus_tag="BSU_02830" /old_locus_tag="BSU02830" /EC_number="1.1.1.-" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 10220166, 11948145, 15805528; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative oxidoreductase" /protein_id="NP_388165.1" /db_xref="EnsemblGenomes-Gn:BSU02830" /db_xref="EnsemblGenomes-Tr:CAB12077" /db_xref="GOA:P80869" /db_xref="InterPro:IPR002347" /db_xref="InterPro:IPR020904" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG12761" /db_xref="UniProtKB/Swiss-Prot:P80869" /translation="MYKDLTGKTAIVTGSSKGIGKAIAERFGKEKMNVVVNYHSDPSG ADETLEIIKQNGGKAVSVEADVSKEEGIQALLDTALEHFGTLDVMVNNSGFNGVEAMP HEMSLEDWQRVIDVNVTGTFLGAKAALNHMMKNNIKGNVLNISSVHQQIPRPVNVQYS TSKGGIKMMTETLALNYADKGIRVNAIAPGTIATESNVDTKKEESRQKQLKKIPMKAF GKPEEVAAAAAWLVSEEASYVTGATLFVDGGMTLYPSQLE*" gene 305658..306434 /gene="ycdF" /locus_tag="BSU_02830" /old_locus_tag="BSU02830" downshifts complement(305665) /Source="Nicolas_upshifts" /id="D116" /incds=0 /nref=10 /ntot=23 /MaxReadThrough="0.31912" /MaxDrop="4.8095" /score="0.506500496" /energy="-5.8" /TU="NA" /idTUdmin="U205" /TUdmin="-1914" /isTUend="FALSE" CDS 306459..308144 /gene="ycdG" /locus_tag="BSU_02840" /old_locus_tag="BSU02840" /EC_number="3.2.1.10" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 11544224; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative oligo-carbohydrate hydrolase" /protein_id="NP_388166.1" /db_xref="EnsemblGenomes-Gn:BSU02840" /db_xref="EnsemblGenomes-Tr:CAB12078" /db_xref="GOA:O34364" /db_xref="InterPro:IPR006047" /db_xref="InterPro:IPR017853" /db_xref="SubtiList:BG12762" /db_xref="UniProtKB/Swiss-Prot:O34364" /translation="MKTDWWKDAVVYQIYPRSFQDSNGDGIGDLRGIISRLDYIKELG ADVIWICPIYPSPNVDYGYDVTNHKAIMDSYGTMDDFHELLDQVHQRGLKLVMDFVLN HTSVEHPWFKEAELDKNSKYRSYYYWRPGTKNGPPTDWLSNYGCPVWQYEEHTGEYYL HMNAVKQADLNWENPEVRQAVYDMMKFWLDKGVDGLRIDQLHLISKKEYLPSYEDYIN QQAEPKPFQPNGERIHDYLKEITDEVFSHYDVMSVGEVGSVTPEEGLKYTGTDKHELN MIFHFQHMELDQQPGKEHWDLKPLELSDLKSVLTKWQKKLEHQGWNTLFWCNHDQPRI VSRFGDDGEYRKASAKMLAAVIYFMKGTPYIYQGEEIGMTNAPFTRIEDYKDIQTINM YHKRVFEKGYDPNDVMRSILAKSRDHARTPMQWNSGKNAGFTDGTPWLKVNPNFTAIN VEEAQGDPDSVLNYYKKLISLRKQYADLMKGSFDLLLPDDPQLFVYMRENSKQQLLSV NNFSKEQAVFQWPKNCGKAQASLLLSNYNNDDLDDEMVFRPYESRVYLLDKTN*" gene 306459..308144 /gene="ycdG" /locus_tag="BSU_02840" /old_locus_tag="BSU02840" promotor_no_box 307399..307499 /Source="Nicolas_upshift_promotors" /id="U207" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.487512487512487" /psig="0.044955044955045" /xcortree=117 /SigmaFactorBS="agaagcttgaacatcaaggctggaatacattgttttggtgca accacgaccagccccggattgtgtccagattcggagacgatggggaataccgcaaagc a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_no_box" upshifts 307459 /Source="Nicolas_upshifts" /id="U207" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.487512487512487" /psig="0.044955044955045" /xcortree=117 /SigmaFactorBS="agaagcttgaacatcaaggctggaatacattgttttggtgca accacgaccagccccggattgtgtccagattcggagacgatggggaataccgcaaagc a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" downshifts 307525 /Source="Nicolas_upshifts" /id="D117" /incds=1 /nref=1 /ntot=1 /MaxReadThrough="7.77365" /MaxDrop="2.18547" /score="23.9074448" /energy="-10.2" /TU="U206" /idTUdmin="U204" /TUdmin=1914 /isTUend="FALSE" downshifts 308141 /Source="Nicolas_upshifts" /id="D118" /incds=0 /nref=13 /ntot=56 /MaxReadThrough="5.8252" /MaxDrop="5.18702" /score="23.9074448" /energy="-10.2" /TU="U206" /idTUdmin="U204" /TUdmin=2530 /isTUend="FALSE" promotor_-35 308235..308242 /Source="Nicolas_upshift_promotors" /id="U208" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.401598401598402" /psig="0.999000999001" /xcortree=669 /SigmaFactorBS="ggcgggaagaataaatgaaaatgaaatttatTCTTGCAAaac gtaatgacttcgGTTTATTATGATATAGGATTacaaaatcgttatcattttgatttaa a" /listShort="adcA, adcC, adcB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 308258..308277 /Source="Nicolas_upshift_promotors" /id="U208" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.401598401598402" /psig="0.999000999001" /xcortree=669 /SigmaFactorBS="ggcgggaagaataaatgaaaatgaaatttatTCTTGCAAaac gtaatgacttcgGTTTATTATGATATAGGATTacaaaatcgttatcattttgatttaa a" /listShort="adcA, adcC, adcB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 308264 /Source="Nicolas_upshifts" /id="U208" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.401598401598402" /psig="0.999000999001" /xcortree=669 /SigmaFactorBS="ggcgggaagaataaatgaaaatgaaatttatTCTTGCAAaac gtaatgacttcgGTTTATTATGATATAGGATTacaaaatcgttatcattttgatttaa a" /listShort="adcA, adcC, adcB" /GFF_Attribute="listLong" CDS 308332..309291 /gene="znuA" /locus_tag="BSU_02850" /old_locus_tag="BSU02850" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 9379902, 12426338, 14730579, 21813502; Product type lp: lipoprotein" /codon_start=1 /transl_table=11 /product="Zn(II)-binding lipoprotein" /protein_id="NP_388167.1" /db_xref="EnsemblGenomes-Gn:BSU02850" /db_xref="EnsemblGenomes-Tr:CAB12079" /db_xref="GOA:O34966" /db_xref="InterPro:IPR006127" /db_xref="InterPro:IPR006128" /db_xref="InterPro:IPR006129" /db_xref="PDB:2O1E" /db_xref="SubtiList:BG12763" /db_xref="UniProtKB/Swiss-Prot:O34966" /translation="MFKKWSGLFVIAACFLLVAACGNSSTKGSADSKGDKLHVVTTFY PMYEFTKQIVKDKGDVDLLIPSSVEPHDWEPTPKDIANIQDADLFVYNSEYMETWVPS AEKSMGQGHAVFVNASKGIDLMEGSEEEHEEHDHGEHEHSHAMDPHVWLSPVLAQKEV KNITAQIVKQDPDNKEYYEKNSKEYIAKLQDLDKLYRTTAKKAEKKEFITQHTAFGYL AKEYGLKQVPIAGLSPDQEPSAASLAKLKTYAKEHNVKVIYFEEIASSKVADTLASEI GAKTEVLNTLEGLSKEEQDKGLGYIDIMKQNLDALKDSLLVKS*" gene 308332..309291 /gene="znuA" /locus_tag="BSU_02850" /old_locus_tag="BSU02850" promotor_-35 308887..308893 /Source="Nicolas_upshift_promotors" /id="U209" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.461538461538462" /psig="0.998001998001998" /xcortree=670 /SigmaFactorBS="aacaaagaatactatgagaaaaatagtaaagaatatATTGCA AaactgcaggatctTGATAAACTATATCGTACAAccgcaaaaaaagcggagaaaaaag a" /listShort="adcC, adcB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 308907..308926 /Source="Nicolas_upshift_promotors" /id="U209" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.461538461538462" /psig="0.998001998001998" /xcortree=670 /SigmaFactorBS="aacaaagaatactatgagaaaaatagtaaagaatatATTGCA AaactgcaggatctTGATAAACTATATCGTACAAccgcaaaaaaagcggagaaaaaag a" /listShort="adcC, adcB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 308911 /Source="Nicolas_upshifts" /id="U209" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.461538461538462" /psig="0.998001998001998" /xcortree=670 /SigmaFactorBS="aacaaagaatactatgagaaaaatagtaaagaatatATTGCA AaactgcaggatctTGATAAACTATATCGTACAAccgcaaaaaaagcggagaaaaaag a" /listShort="adcC, adcB" /GFF_Attribute="listLong" downshifts 309263 /Source="Nicolas_upshifts" /id="D119" /incds=0 /nref=140 /ntot=250 /MaxReadThrough="6.07181" /MaxDrop="5.15011" /score="8.99106569" /energy="-15.9" /TU="U206,U208,U209" /idTUdmin="U206" /TUdmin="-1562" /isTUend="FALSE" CDS 309347..310042 /gene="znuC" /locus_tag="BSU_02860" /old_locus_tag="BSU02860" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:9379902, 9811636, 21813502" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9379902, 9811636, 21813502; Product type t: transporter" /codon_start=1 /transl_table=11 /product="Zn(II) transporter (ATP-binding protein)" /protein_id="NP_388168.1" /db_xref="EnsemblGenomes-Gn:BSU02860" /db_xref="EnsemblGenomes-Tr:CAB12080" /db_xref="GOA:O34946" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR017871" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG12764" /db_xref="UniProtKB/Swiss-Prot:O34946" /translation="MNLVSLKDIVFGYSHTPVLDKVSLDIESGEFVGITGPNGASKST LIKVMLGMLKPWEGTVTISKRNTEGKRLTIGYVPQQISSFNAGFPSTVLELVQSGRYT KGKWFKRLNEEDHLEVEKALKMVEMWDLRHRKIGDLSGGQKQKICIARMLASNPDLLM LDEPTTAVDYDSRKGFYEFMHHLVKNHNRTVVMVTHEQNEVQQFLDKVIRLERGEKGG WKCLTWNSCDELF*" gene 309347..310042 /gene="znuC" /locus_tag="BSU_02860" /old_locus_tag="BSU02860" CDS 310000..310842 /gene="znuB" /locus_tag="BSU_02870" /old_locus_tag="BSU02870" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:15849754, 16850406, 9379902, 9811636, 21813502" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15849754, 16850406, 9379902, 9811636, 21813502; Product type t: transporter" /codon_start=1 /transl_table=11 /product="high affinity Zn(II) ABC transporter (permease)" /protein_id="NP_388169.1" /db_xref="EnsemblGenomes-Gn:BSU02870" /db_xref="EnsemblGenomes-Tr:CAB12081" /db_xref="GOA:O34610" /db_xref="InterPro:IPR001626" /db_xref="InterPro:IPR035568" /db_xref="SubtiList:BG12765" /db_xref="UniProtKB/Swiss-Prot:O34610" /translation="MEMFDLEFMRRAFLAGGMIAVMAPILGVYLVLRRQALMADTLSH ISLSGVAIGFFLSTNITAASIVVVTIGAIGIEYMRRAYRTYSEVSIAILMAAGLSFAM FLISLSKGTANMSIDQYLFGSLVTVNQQQVYIISIITLLILLYFIVLRRPLYLLTFDE ATAKTSGINTNVLSLSFSIVTGLAISVIIPIIGVLLVSALLVLPAAFAIRIAKGFNMV FITAILISLFSVFTGLTSSYQLGTPPGPSITLLLIVLLLIGFAVQGVWTFIKKEAQRK KRSR*" gene 310000..310842 /gene="znuB" /locus_tag="BSU_02870" /old_locus_tag="BSU02870" downshifts 310829 /Source="Nicolas_upshifts" /id="D120" /incds=0 /nref=168 /ntot=266 /MaxReadThrough="2.4865" /MaxDrop="6.44929" /score="27.8218406" /energy="-13.6" /TU="NA" /idTUdmin="U206" /TUdmin=4 /isTUend="TRUE" CDS complement(310880..311875) /gene="yceB" /locus_tag="BSU_02880" /old_locus_tag="BSU02880" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 16428414; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative luciferase-like monooxygenase" /protein_id="NP_388170.2" /db_xref="EnsemblGenomes-Gn:BSU02880" /db_xref="EnsemblGenomes-Tr:CAB12082" /db_xref="GOA:O34504" /db_xref="InterPro:IPR011251" /db_xref="InterPro:IPR019949" /db_xref="InterPro:IPR036661" /db_xref="SubtiList:BG12766" /db_xref="UniProtKB/Swiss-Prot:O34504" /translation="MIHLSILDQAPVSKGESPVTTLQHSVELAQLSEQWGYKRYWFAE HHSTKGLASTAPEIMIARIAAQTNTIRVGSGGVLLPQYSPFKVAETFRQLEALYPNRI DLGVGRSPGGTTKTRLALTDGVKKSLTEFNRQLQDVSYFLTDSLPPDHPYAGIKAAPL IGTAPELWVLGLGENSARRAAHQGIGYVFGHFINPERGENAFRIYRESFRPSAHFSNP SALFTIFVICAKTDEEAEELALSQDLWLLRVGKGLDSRVPSIEEAKAHPYTASDKKLI EENRKRMVIGSPTTVKQQLLDLTGCYETNEIMVLCNVFDFEAKKESYERLAELFL*" gene complement(310880..311875) /gene="yceB" /locus_tag="BSU_02880" /old_locus_tag="BSU02880" promotor_-35 311831..311838 /Source="Nicolas_upshift_promotors" /id="U210" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.661338661338661" /psig="0.997002997002997" /xcortree=1949 /SigmaFactorBS="accgaatgctggagagttgtcacagggctttcTCCTTTAGaa acaggtgcctgaTCAAGTATGCTTAAATGAATcaaaaggccgcttcctttctgtctgt t" /listShort="S105" /listLong="S106, yceC, yceD, yceE, yceF, yceG, yceH" /label="promotor_-35" promotor_-10 311853..311872 /Source="Nicolas_upshift_promotors" /id="U210" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.661338661338661" /psig="0.997002997002997" /xcortree=1949 /SigmaFactorBS="accgaatgctggagagttgtcacagggctttcTCCTTTAGaa acaggtgcctgaTCAAGTATGCTTAAATGAATcaaaaggccgcttcctttctgtctgt t" /listShort="S105" /listLong="S106, yceC, yceD, yceE, yceF, yceG, yceH" /label="promotor_-10" S_feature 311859..312061 /Source="Nicolas_S_feature" /locus_tag="new_311859_312061" /HighExp="Diami, Etha, dia5, Salt, H2O2, dia15, Paraq, T-0.40H, T0.30H, G135" /AntisenseName="yceB" /AntisenseCor="0.84300534435872998" /AntisenseRegPval="-73.099999999999994" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.997" /TUlongSig="NA" /TUlongPSig="NA" /label="S105" upshifts 311859 /Source="Nicolas_upshifts" /id="U210" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.661338661338661" /psig="0.997002997002997" /xcortree=1949 /SigmaFactorBS="accgaatgctggagagttgtcacagggctttcTCCTTTAGaa acaggtgcctgaTCAAGTATGCTTAAATGAATcaaaaggccgcttcctttctgtctgt t" /listShort="S105" /listLong="S106, yceC, yceD, yceE, yceF, yceG, yceH" promotor_-10 complement(311907..311926) /Source="Nicolas_upshift_promotors" /id="U211" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.98901098901099" /psig="0.992007992007992" /xcortree=1952 /SigmaFactorBS="gctataaagtgcgcttcttaaacaaacCATTTGACgcgggca agtcattTTGCCTATTCTGGTGTCACCatctaaaaacagacagaaaggaagcggcctt t" /listShort="yceB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(311915) /Source="Nicolas_upshifts" /id="U211" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.98901098901099" /psig="0.992007992007992" /xcortree=1952 /SigmaFactorBS="gctataaagtgcgcttcttaaacaaacCATTTGACgcgggca agtcattTTGCCTATTCTGGTGTCACCatctaaaaacagacagaaaggaagcggcctt t" /listShort="yceB" /GFF_Attribute="listLong" promotor_-35 complement(311941..311948) /Source="Nicolas_upshift_promotors" /id="U211" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.98901098901099" /psig="0.992007992007992" /xcortree=1952 /SigmaFactorBS="gctataaagtgcgcttcttaaacaaacCATTTGACgcgggca agtcattTTGCCTATTCTGGTGTCACCatctaaaaacagacagaaaggaagcggcctt t" /listShort="yceB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 312045..312054 /Source="Nicolas_upshift_promotors" /id="U212" /multdbtbs="SigA,SigW" /comp="M9" /sig="SigWXY" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1676 /SigmaFactorBS="agttttttttcgaggtttttcgtcaattattcttaactttta CGAAACTTTGatataataacaaACGTATATATTAGTAAtttacggcttattttccttg t" /listShort="S106, yceC, yceD, yceE, yceF, yceG, yceH, yceI" /GFF_Attribute="listLong" /label="promotor_-35" S_feature 312063..312158 /Source="Nicolas_S_feature" /locus_tag="new_312063_312158" /HighExp="T0.0H, T-0.40H, T-1.10H, T0.30H, Salt, T1.0H, Etha, T-1.40H, T1.30H, T2.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigWXY" /TUshortPSig="0.999" /TUlongSig="SigA" /TUlongPSig="0.997" /label="S106" upshifts 312063 /Source="Nicolas_upshifts" /id="U212" /multdbtbs="SigA,SigW" /comp="M9" /sig="SigWXY" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1676 /SigmaFactorBS="agttttttttcgaggtttttcgtcaattattcttaactttta CGAAACTTTGatataataacaaACGTATATATTAGTAAtttacggcttattttccttg t" /listShort="S106, yceC, yceD, yceE, yceF, yceG, yceH, yceI" /GFF_Attribute="listLong" promotor_-10 312067..312082 /Source="Nicolas_upshift_promotors" /id="U212" /multdbtbs="SigA,SigW" /comp="M9" /sig="SigWXY" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1676 /SigmaFactorBS="agttttttttcgaggtttttcgtcaattattcttaactttta CGAAACTTTGatataataacaaACGTATATATTAGTAAtttacggcttattttccttg t" /listShort="S106, yceC, yceD, yceE, yceF, yceG, yceH, yceI" /GFF_Attribute="listLong" /label="promotor_-10" CDS 312159..312758 /gene="yceC" /locus_tag="BSU_02890" /old_locus_tag="BSU02890" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 24366250; Product type f: factor" /codon_start=1 /transl_table=11 /product="putative stress adaptation protein (tellurite resistance)" /protein_id="NP_388171.1" /db_xref="EnsemblGenomes-Gn:BSU02890" /db_xref="EnsemblGenomes-Tr:CAB12083" /db_xref="GOA:P81100" /db_xref="InterPro:IPR003325" /db_xref="SubtiList:BG12767" /db_xref="UniProtKB/Swiss-Prot:P81100" /translation="MAISLEKGQRIDLTKGKAGLSKLMVGLGWDPVSSGGGFFSKLLG GGGPNIDCDASVLMLENGKFTDKKNLIYFGNLKSRCGGVQHTGDNLTGDGAGDDEQIM IDLDKVPGNIDKLVFVVNIYDCVRRKQDFGMIQNAFIRVVDQSNHEEMLKYNLRDNYA GRTSLITAEIYRSGSEWKFAAVGEGTNDTRLEDIISRYV*" gene 312159..312758 /gene="yceC" /locus_tag="BSU_02890" /old_locus_tag="BSU02890" CDS 312780..313361 /gene="yceD" /locus_tag="BSU_02900" /old_locus_tag="BSU02900" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 22720735, 24366250; Product type f: factor" /codon_start=1 /transl_table=11 /product="putative stress adaptation protein (tellurite resistance)" /protein_id="NP_388172.1" /db_xref="EnsemblGenomes-Gn:BSU02900" /db_xref="EnsemblGenomes-Tr:CAB12084" /db_xref="GOA:P80875" /db_xref="InterPro:IPR003325" /db_xref="SubtiList:BG12768" /db_xref="UniProtKB/Swiss-Prot:P80875" /translation="MTISLAKGQKVDLTKTNPGLSKVVVGLGWDTNKYDGGHDFDLDS SVFLLDAAGKCASPNDFIFYNQLEGGNGSVVHSGDNLTGAGEGDDENVKVNLSAVPAN IDKISFVITIHDAEARSQNFGQVSNAFVRIVNEETNEELIRYDLAEDFSIETAIIAGE LYRHNGEWKFSAIGSGYQGGLARIATDYGLQVG*" gene 312780..313361 /gene="yceD" /locus_tag="BSU_02900" /old_locus_tag="BSU02900" CDS 313396..313974 /gene="yceE" /locus_tag="BSU_02910" /old_locus_tag="BSU02910" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 22720735, 24366250, 25355936; Product type f: factor" /codon_start=1 /transl_table=11 /product="putative stress adaptation protein (tellurite resistance)" /protein_id="NP_388173.1" /db_xref="EnsemblGenomes-Gn:BSU02910" /db_xref="EnsemblGenomes-Tr:CAB12085" /db_xref="GOA:O34384" /db_xref="InterPro:IPR003325" /db_xref="SubtiList:BG12769" /db_xref="UniProtKB/Swiss-Prot:O34384" /translation="MAIQLSKGQRIDLTKTNPGLTKAVIGLGWDTNKYSGGHDFDLDA SAFLVDAHDNCVNDLDFVFYNNLEHPSGGVIHTGDNRTGEGDGDDEQIIVDFSKIPAH IEKIGITVTIHDAEARSQNFGQVSNAFVRVVDEETQNELLRFDLGEDFSIETAVVVCE LYRHGGEWKFNAIGSGFSGGLAALCRNYGLQV*" gene 313396..313974 /gene="yceE" /locus_tag="BSU_02910" /old_locus_tag="BSU02910" CDS 314025..314798 /gene="yceF" /locus_tag="BSU_02920" /old_locus_tag="BSU02920" /function="16.8: Protect" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406, 22720735, 24366250; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative stress adaptation transporter (tellurite resistance)" /protein_id="NP_388174.1" /db_xref="EnsemblGenomes-Gn:BSU02920" /db_xref="EnsemblGenomes-Tr:CAB12086" /db_xref="GOA:O34447" /db_xref="InterPro:IPR005496" /db_xref="InterPro:IPR022493" /db_xref="SubtiList:BG12770" /db_xref="UniProtKB/Swiss-Prot:O34447" /translation="MDFLHHILSTYASFFDWKMWGEVLTDPVSWGLIGSLVVLEGLLS ADNALVLAVMVKHLPEKQRKKALTYGLFGAYIFRFIFIGLGMLLIKFWWIKVLGALYL AWLVIKHFWIGEKEEEADGMKKNSWMVRTFGIFWATVISVELMDLAFSVDSILAAFAV SEKVWVLLIGGMLGILMMRTVAKVFLVLIDKIPELENTAFVLIGIIALKMAGSAFHYE MPHSVFFIIIIAAFAVTLIIHYINKQKQVREQTAASKEE*" gene 314025..314798 /gene="yceF" /locus_tag="BSU_02920" /old_locus_tag="BSU02920" downshifts 314785 /Source="Nicolas_upshifts" /id="D121" /incds=0 /nref=46 /ntot=239 /MaxReadThrough="6.82513" /MaxDrop="4.0674" /score="4.0495978" /energy="-8.2" /TU="U212" /idTUdmin="U210" /TUdmin=2728 /isTUend="FALSE" CDS 314883..316496 /gene="yceG" /locus_tag="BSU_02930" /old_locus_tag="BSU02930" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 24366250; Product type f: factor" /codon_start=1 /transl_table=11 /product="putative toxic compound adaptation protein (tellurite resistance)" /protein_id="NP_388175.1" /db_xref="EnsemblGenomes-Gn:BSU02930" /db_xref="EnsemblGenomes-Tr:CAB12087" /db_xref="InterPro:IPR025647" /db_xref="SubtiList:BG12771" /db_xref="UniProtKB/Swiss-Prot:O34809" /translation="MRQEELTIHKALPADGDWKSLLFQPLPERDHYETAQGLSFSRLA GQILGTPIDETDYYNELYELSVNDRITILSETLDKTIEPETFQKLQHIHSINQKEKGL SVSRFVAFLDGEKLIAKHSNPLMHRHLRKALMTLLHTFADSHEKGLNHPDFRRVLLDV SKFSLNHLNPWLEKTDIEREMPKVVWYGDATKSQLYFLYYLMLVGCDVLLFHPAGTDQ LALVDPKQELGFTEKLPDVSELQPFPKEKPDRKSTVAYRSTKEIEHVLNHEESMLYKP WQFRDHTPVSVTLKTTYDELFLITKERAFIRPNFKADKHSIEIPNVFAKIMGVSKDNK EYWNRLHTLADYQETEMVRSFPFTEEIKSNYQFHYSHALDQEGNIDPDKLMASNVWQY KQLPAGVQTAIAKTISRMCRYPRLKALHQEQVKDVQIYLFKQTTNLPANLLKLIQMFD YAQTVPKLVLYHTEMSGGLTRSDAAALLFLNEIGIDIIIYNPPGHQDIEQFIEEDQYD IHWLDDMVFQQDYKEPSLVKRLFRTITQK*" gene 314883..316496 /gene="yceG" /locus_tag="BSU_02930" /old_locus_tag="BSU02930" CDS 316512..317603 /gene="yceH" /locus_tag="BSU_02940" /old_locus_tag="BSU02940" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 22720735, 24366250; Product type f: factor" /codon_start=1 /transl_table=11 /product="putative reactive oxygen species resistance protein" /protein_id="NP_388176.1" /db_xref="EnsemblGenomes-Gn:BSU02940" /db_xref="EnsemblGenomes-Tr:CAB12088" /db_xref="InterPro:IPR008863" /db_xref="SubtiList:BG12772" /db_xref="UniProtKB/Swiss-Prot:O34833" /translation="MTTENQNPLVLDKNEEISQQKADDIRLQLRQEPEVKRLAQQIDV KNQMELLEYGKEPAVEISKFSDRILGMMKTTSVTDSGTMLTQLGKIMDRFDKNDFDEP KGLMAKIFKRGGSMIEKIFKKYQTLGGEIEKIHVEISKYKDEMTKTNYTLDEMYENNI KYYMELEKYVVAGQMKLEEMQSILPSYEEKAASGNQLAQMQLDTLRNGIQALEERVYD LDMARMVALQTAPQIRLLQRGNAKLIGKINSAFIITIPIFKNGIIQAVTVKRQKLVAD SMSELDRRTNEMLKRNAENISSQSVEIARMAGRPSIDIETIESSWNTIVSGMQETKQI EEENKRLREDGARRIAQLQDNIKKAALQQ*" gene 316512..317603 /gene="yceH" /locus_tag="BSU_02940" /old_locus_tag="BSU02940" downshifts 317577 /Source="Nicolas_upshifts" /id="D122" /incds=0 /nref=85 /ntot=228 /MaxReadThrough="4.46836" /MaxDrop="4.05585" /score="-6.59172775" /energy="-17.5" /TU="U212" /idTUdmin="U212" /TUdmin="-1322" /isTUend="FALSE" promotor_-35 317657..317664 /Source="Nicolas_upshift_promotors" /id="U213" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.977022977022977" /psig="0.998001998001998" /xcortree=2427 /SigmaFactorBS="aagcggggtatttcaattacatcatttagtTAATGACAatgt gtaaagacagGTGTAAACTTAAACGGTAATcattttgcatatcagaggtgttggcaat g" /listShort="yceI" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 317679..317698 /Source="Nicolas_upshift_promotors" /id="U213" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.977022977022977" /psig="0.998001998001998" /xcortree=2427 /SigmaFactorBS="aagcggggtatttcaattacatcatttagtTAATGACAatgt gtaaagacagGTGTAAACTTAAACGGTAATcattttgcatatcagaggtgttggcaat g" /listShort="yceI" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 317687 /Source="Nicolas_upshifts" /id="U213" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.977022977022977" /psig="0.998001998001998" /xcortree=2427 /SigmaFactorBS="aagcggggtatttcaattacatcatttagtTAATGACAatgt gtaaagacagGTGTAAACTTAAACGGTAATcattttgcatatcagaggtgttggcaat g" /listShort="yceI" /GFF_Attribute="listLong" CDS 317725..318927 /gene="niaP" /locus_tag="BSU_02950" /old_locus_tag="BSU02950" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:15849754, 16850406, 18276644, 21953179" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15849754, 16850406, 18276644, 21953179; Product type t: transporter" /codon_start=1 /transl_table=11 /product="niacin permease" /protein_id="NP_388177.1" /db_xref="EnsemblGenomes-Gn:BSU02950" /db_xref="EnsemblGenomes-Tr:CAB12089" /db_xref="GOA:O34691" /db_xref="InterPro:IPR005829" /db_xref="InterPro:IPR011701" /db_xref="InterPro:IPR020846" /db_xref="InterPro:IPR036259" /db_xref="SubtiList:BG12773" /db_xref="UniProtKB/Swiss-Prot:O34691" /translation="MGKQQPISQRKLLGVAGLGWLFDAMDVGILSFIIAALHVEWNLS PEEMKWIGSVNSIGMAAGAFLFGLLADRIGRKKVFIITLLCFSIGSGISAFVTSLSAF LILRFVIGMGLGGELPVASTLVSEAVVPEKRGRVIVLLESFWAVGWLAAALISYFVIP SFGWQAALLLTALTAFYALYLRTSLPDSPKYESLSAKKRSMWENVKSVWARQYIRPTV MLSIVWFCVVFSYYGMFLWLPSVMLLKGFSMIQSFEYVLLMTLAQLPGYFSAAWLIEK AGRKWILVVYLIGTAGSAYFFGTADSLSLLLTAGVLLSFFNLGAWGVLYAYTPEQYPT AIRATGSGTTAAFGRIGGIFGPLLVGTLAARHISFSVIFSIFCIAILLAVACILIMGK ETKQTELE*" gene 317725..318927 /gene="niaP" /locus_tag="BSU_02950" /old_locus_tag="BSU02950" downshifts 318907 /Source="Nicolas_upshifts" /id="D123" /incds=0 /nref=8 /ntot=184 /MaxReadThrough="4.1968" /MaxDrop="3.48367" /score="13.0427769" /energy="-10.6" /TU="U213" /idTUdmin="U212" /TUdmin=8 /isTUend="TRUE" CDS complement(319180..320352) /gene="yceJ" /locus_tag="BSU_02960" /old_locus_tag="BSU02960" /function="16.8: Protect" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative carbohydrate transporter (possibly exporter)" /protein_id="NP_388178.1" /db_xref="EnsemblGenomes-Gn:BSU02960" /db_xref="EnsemblGenomes-Tr:CAB12090" /db_xref="GOA:O34724" /db_xref="InterPro:IPR001958" /db_xref="InterPro:IPR011701" /db_xref="InterPro:IPR020846" /db_xref="InterPro:IPR036259" /db_xref="SubtiList:BG12774" /db_xref="UniProtKB/Swiss-Prot:O34724" /translation="MNRIWLFFSVMFVIGTDTFLLSPLLPLLQDQFHVSTDLSGWMVS AYALGYALFAFIAGPISDRLNRKTVMLWGLAGFIVSTFLCGIAPSFAAMCLFRFAAGV SAAFVTPQIWASIPVIVQPSQIIKGMGIATAGLAASQMLGLPIGGFLASFTWHTPFFV LSACSLILLLILAAVMPGIRPSEPLARPSIVNPYRELFSLPKTSVILLAYFLFQTGNF ASFSFLGTWLSADYHLTVSQIGAAMLVLGLGNMLGSLIGSRVSEKLGMFKTLISGMLL MGALYFALPFFPNLFLVEAGFFLTFFTAGIIFPLMMGVFQSIAPNARGTIASLSNAAM YAGTTVGTSIAGFLYQSTQHFGAVTGFTAILFILSMTLYQTISKTGKRQSTARAQL*" gene complement(319180..320352) /gene="yceJ" /locus_tag="BSU_02960" /old_locus_tag="BSU02960" downshifts complement(319195) /Source="Nicolas_upshifts" /id="D124" /incds=0 /nref=1 /ntot=7 /MaxReadThrough="2.6211" /MaxDrop="2.7452" /score="9.21991741" /energy="-12.6" /TU="NA" /idTUdmin="U214" /TUdmin=0 /isTUend="TRUE" CDS complement(320421..320723) /gene="yceK" /locus_tag="BSU_02970" /old_locus_tag="BSU02970" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative transcriptional regulator (ArsR family)" /protein_id="NP_388179.1" /db_xref="EnsemblGenomes-Gn:BSU02970" /db_xref="EnsemblGenomes-Tr:CAB12091" /db_xref="GOA:O34464" /db_xref="InterPro:IPR001845" /db_xref="InterPro:IPR011991" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG12775" /db_xref="UniProtKB/Swiss-Prot:O34464" /translation="MYYSFMTMKQSDDQIRAQIFKALSDESRLAIIRTLYVSGKELSC GEVGEKCNIVKTTASYHFKTLREAGLTATRKDSRTKYVSLREDTFQTYLPGFLETL*" gene complement(320421..320723) /gene="yceK" /locus_tag="BSU_02970" /old_locus_tag="BSU02970" downshifts complement(320449) /Source="Nicolas_upshifts" /id="D125" /incds=0 /nref=221 /ntot=261 /MaxReadThrough="5.67096" /MaxDrop="6.89889" /score="2.01231069" /energy="-4.8" /TU="U214" /idTUdmin="U214" /TUdmin="-1254" /isTUend="FALSE" promotor_-10 complement(320706..320725) /Source="Nicolas_upshift_promotors" /id="U214" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.455544455544456" /psig="0.999000999001" /xcortree=635 /SigmaFactorBS="ccttcctcttatgacttcctgctcctttactggaaaaataAG TTGCTttttcaacacccaTTATGTATTATAGTTTCATGactatgaaacaatcagatga t" /listShort="yceK, yceJ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(320725) /Source="Nicolas_upshifts" /id="U214" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.455544455544456" /psig="0.999000999001" /xcortree=635 /SigmaFactorBS="ccttcctcttatgacttcctgctcctttactggaaaaataAG TTGCTttttcaacacccaTTATGTATTATAGTTTCATGactatgaaacaatcagatga t" /listShort="yceK, yceJ" /GFF_Attribute="listLong" promotor_-35 complement(320739..320745) /Source="Nicolas_upshift_promotors" /id="U214" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.455544455544456" /psig="0.999000999001" /xcortree=635 /SigmaFactorBS="ccttcctcttatgacttcctgctcctttactggaaaaataAG TTGCTttttcaacacccaTTATGTATTATAGTTTCATGactatgaaacaatcagatga t" /listShort="yceK, yceJ" /GFF_Attribute="listLong" /label="promotor_-35" misc_feature 320972..320991 /Source="Nicolas_upshift_promotors" /id="U215" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.555444555444555" /psig="0.99100899100899" /xcortree=2422 /SigmaFactorBS="gtttataaagaaatggtacagaataaaagagaatatgctgtt tgtgtgggaagttacataAATGTTACGGTAATAAAGATtgcttaatatggagggaaaa t" /listShort="opuAA, opuAB, opuAC" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 320972 /Source="Nicolas_upshifts" /id="U215" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.555444555444555" /psig="0.99100899100899" /xcortree=2422 /SigmaFactorBS="gtttataaagaaatggtacagaataaaagagaatatgctgtt tgtgtgggaagttacataAATGTTACGGTAATAAAGATtgcttaatatggagggaaaa t" /listShort="opuAA, opuAB, opuAC" /GFF_Attribute="listLong" CDS 321013..322269 /gene="opuAA" /locus_tag="BSU_02980" /old_locus_tag="BSU02980" /function="16.1: Circulate" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:7622480, 16225868, 16645306, 25012968" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7622480, 16225868, 16645306, 25012968; Product type t: transporter" /codon_start=1 /transl_table=11 /product="L-proline betaine and betonicine ABC transporter(ATP-binding protein)" /protein_id="NP_388180.2" /db_xref="EnsemblGenomes-Gn:BSU02980" /db_xref="EnsemblGenomes-Tr:CAB12092" /db_xref="GOA:P46920" /db_xref="InterPro:IPR000644" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR005892" /db_xref="InterPro:IPR017871" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG11370" /db_xref="UniProtKB/Swiss-Prot:P46920" /translation="MSVDEKPIKIKVEKVSKIFGKQTKKAVQMLANGKTKKEILKATG STVGVNQADFEVYDGEIFVIMGLSGSGKSTLVRMLNRLIEPTAGNIYIDGDMITNMSK DQLREVRRKKISMVFQKFALFPHRTILENTEYGLELQGVDKQERQQKALESLKLVGLE GFEHQYPDQLSGGMQQRVGLARALTNDPDILLMDEAFSALDPLIRKDMQDELLDLHDN VGKTIIFITHDLDEALRIGDRIVLMKDGNIVQIGTPEEILMNPSNEYVEKFVEDVDLS KVLTAGHIMKRAETVRIDKGPRVALTLMKNLGISSIYAVDKQKKLLGVIYASDAKKAA ESDLSLQDILNTEFTTVPENTYLTEIFDVVSDANIPIAVVDEKQRMKGIVVRGALIGA LAGNNEYINAEGTNEQTQDPSAQEVK*" gene 321013..322269 /gene="opuAA" /locus_tag="BSU_02980" /old_locus_tag="BSU02980" downshifts complement(321021) /Source="Nicolas_upshifts" /id="D126" /incds=0 /nref=108 /ntot=175 /MaxReadThrough="2.83797" /MaxDrop="5.18503" /score="2.01231069" /energy="-4.8" /TU="NA" /idTUdmin="U214" /TUdmin="-1826" /isTUend="FALSE" CDS 322271..323119 /gene="opuAB" /locus_tag="BSU_02990" /old_locus_tag="BSU02990" /function="16.1: Circulate" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:8752321, 15849754, 16225868, 16645306, 16850406, 25012968" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8752321, 15849754, 16225868, 16645306, 16850406, 25012968; Product type t : transporter" /codon_start=1 /transl_table=11 /product="L-proline betaine and betonicine ABC transporter(permease)" /protein_id="NP_388181.1" /db_xref="EnsemblGenomes-Gn:BSU02990" /db_xref="EnsemblGenomes-Tr:CAB12093" /db_xref="GOA:P46921" /db_xref="InterPro:IPR000515" /db_xref="InterPro:IPR035906" /db_xref="SubtiList:BG11371" /db_xref="UniProtKB/Swiss-Prot:P46921" /translation="MDRLPRIPLADIIDRFVDWITMTFGGFFDGIANGLAAFVNGIVT GLGFIPSILLTIIFAALAWWISTRGIALFTLIGFLLIDYLGYWDPMLQTLALVLTSVI ISIVVGVPIGIWASQKETVRRIVTPILDLMQTMPAFVYLLPAIFFFNIGVVPGVVASV IFAMPPTIRMTVLGIKQVPADLIEATEAFGSTTAQRLFKVQLPLATKTILAGINQSIM LALSMVVIAAMVGAPGLGSEVYSAVTQLKTGVGVEAGIAIVIVAITLDRITQNIKVKK KSRGNA*" gene 322271..323119 /gene="opuAB" /locus_tag="BSU_02990" /old_locus_tag="BSU02990" CDS 323119..324000 /gene="opuAC" /locus_tag="BSU_03000" /old_locus_tag="BSU03000" /function="16.1: Circulate" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:7622480, 16225868, 16645306, 25012968" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7622480, 16225868, 16645306, 25012968; Product type lp: lipoprotein" /codon_start=1 /transl_table=11 /product="L-proline betaine and betonicine ABC transporterABC transporter (glycine betaine-binding lipoprotein)" /protein_id="NP_388182.1" /db_xref="EnsemblGenomes-Gn:BSU03000" /db_xref="EnsemblGenomes-Tr:CAB12094" /db_xref="GOA:P46922" /db_xref="InterPro:IPR007210" /db_xref="PDB:2B4L" /db_xref="PDB:2B4M" /db_xref="PDB:3CHG" /db_xref="SubtiList:BG11372" /db_xref="UniProtKB/Swiss-Prot:P46922" /translation="MLKKIIGIGVSAMLALSLAACGSENDENASAAEQVNKTIIGIDP GSGIMSLTDKAMKDYDLNDWTLISASSAAMTATLKKSYDRKKPIIITGWTPHWMFSRY KLKYLDDPKQSYGSAEEIHTITRKGFSKEQPNAAKLLSQFKWTQDEMGEIMIKVEEGE KPAKVAAEYVNKHKDQIAEWTKGVQKVKGDKINLAYVAWDSEIASTNVIGKVLEDLGY EVTLTQVEAGPMWTAIATGSADASLSAWLPNTHKAYAAKYKGKYDDIGTSMTGVKMGL VVPQYMKNVNSIEDLKK*" gene 323119..324000 /gene="opuAC" /locus_tag="BSU_03000" /old_locus_tag="BSU03000" downshifts 323981 /Source="Nicolas_upshifts" /id="D127" /incds=0 /nref=254 /ntot=269 /MaxReadThrough="0.74967" /MaxDrop="8.21394" /score="33.6263027" /energy="-12.2" /TU="NA" /idTUdmin="U215" /TUdmin=0 /isTUend="TRUE" downshifts complement(324013) /Source="Nicolas_upshifts" /id="D128" /incds=0 /nref=2 /ntot=62 /MaxReadThrough="4.29566" /MaxDrop="3.9514" /score="29.8489328" /energy="-12.2" /TU="U216" /idTUdmin="U216" /TUdmin="-220" /isTUend="FALSE" CDS complement(324038..325189) /gene="amhX" /locus_tag="BSU_03010" /old_locus_tag="BSU03010" /EC_number="3.5.1.-" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 8768514; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative amidohydrolase" /protein_id="NP_388183.2" /db_xref="EnsemblGenomes-Gn:BSU03010" /db_xref="EnsemblGenomes-Tr:CAB12095" /db_xref="GOA:P54983" /db_xref="InterPro:IPR002933" /db_xref="InterPro:IPR011650" /db_xref="InterPro:IPR017439" /db_xref="InterPro:IPR036264" /db_xref="SubtiList:BG11789" /db_xref="UniProtKB/Swiss-Prot:P54983" /translation="MQKLSEEMKQTIMDIFEHLHANPEVSWKEYETTSFLKQKLEDLG CRTRTFSDCTGVVGEIGSGSPVVAVRADIDALWQEVNGTFRANHSCGHDSHMTMALGT LMLLKKQPELPKGTIRFIFQPAEEKGGGALKMIEEGVLDDIDYLYGVHVRPIQETQNG RCAPSILHGSSQHIEGTIIGEEAHGARPHLGKNSIEIAAFLVHKLGLIHIDPQIPHTV KMTKLQAGGESSNIIPGKASFSLDLRAQTNEAMEALIAETERACEAAAAAFGAKIELH KEHSLPAATQNKEAEAIMAEAITEIIGAERLDDPLVTTGGEDFHFYAVKVPNLKTTML GLGCGLQPGLHHPHMTFDRNAMFTGIHILANAVLKTFQKAESLAAANAS*" gene complement(324038..325189) /gene="amhX" /locus_tag="BSU_03010" /old_locus_tag="BSU03010" downshifts complement(324057) /Source="Nicolas_upshifts" /id="D129" /incds=0 /nref=2 /ntot=70 /MaxReadThrough="4.33606" /MaxDrop="3.5225" /score="29.8489328" /energy="-12.2" /TU="U216" /idTUdmin="U216" /TUdmin="-264" /isTUend="FALSE" S_feature complement(325190..325277) /Source="Nicolas_S_feature" /locus_tag="new_325190_325277_c" /HighExp="Etha, T1.30H, M9-stat, T2.30H, S1, T3.30H, T5.0H, T4.0H, Sw, T3.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S107" promotor_-35 325245..325252 /Source="Nicolas_upshift_promotors" /id="U217" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.758241758241758" /psig="0.999000999001" /xcortree=2902 /SigmaFactorBS="atttttaccttctttactttatttaTATTGAAAcaggaagat aggctGTATATAATATAGCACATATtgctactattcagaataattaatattttcaaac a" /listShort="ycgA" /listLong="ycgB, S108, amyE" /label="promotor_-35" promotor_-10 complement(325264..325283) /Source="Nicolas_upshift_promotors" /id="U216" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.632367632367632" /psig=1 /xcortree=2878 /SigmaFactorBS="tttcgatccatcccctctgtttgaaaatattaattATTCTGA atagtagcaataTGTGCTATATTATATACAGCctatcttcctgtttcaatataaataa a" /listShort="S107, amhX" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-10 325267..325286 /Source="Nicolas_upshift_promotors" /id="U217" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.758241758241758" /psig="0.999000999001" /xcortree=2902 /SigmaFactorBS="atttttaccttctttactttatttaTATTGAAAcaggaagat aggctGTATATAATATAGCACATATtgctactattcagaataattaatattttcaaac a" /listShort="ycgA" /listLong="ycgB, S108, amyE" /label="promotor_-10" upshifts complement(325277) /Source="Nicolas_upshifts" /id="U216" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.632367632367632" /psig=1 /xcortree=2878 /SigmaFactorBS="tttcgatccatcccctctgtttgaaaatattaattATTCTGA atagtagcaataTGTGCTATATTATATACAGCctatcttcctgtttcaatataaataa a" /listShort="S107, amhX" /GFF_Attribute="listLong" upshifts 325280 /Source="Nicolas_upshifts" /id="U217" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.758241758241758" /psig="0.999000999001" /xcortree=2902 /SigmaFactorBS="atttttaccttctttactttatttaTATTGAAAcaggaagat aggctGTATATAATATAGCACATATtgctactattcagaataattaatattttcaaac a" /listShort="ycgA" /listLong="ycgB, S108, amyE" promotor_-35 complement(325296..325302) /Source="Nicolas_upshift_promotors" /id="U216" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.632367632367632" /psig=1 /xcortree=2878 /SigmaFactorBS="tttcgatccatcccctctgtttgaaaatattaattATTCTGA atagtagcaataTGTGCTATATTATATACAGCctatcttcctgtttcaatataaataa a" /listShort="S107, amhX" /GFF_Attribute="listLong" /label="promotor_-35" CDS 325339..326772 /gene="ycgA" /locus_tag="BSU_03020" /old_locus_tag="BSU03020" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406, 21747963, 21764931; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative branched chain amino acid permease" /protein_id="NP_388184.2" /db_xref="EnsemblGenomes-Gn:BSU03020" /db_xref="EnsemblGenomes-Tr:CAB12096" /db_xref="GOA:P55908" /db_xref="InterPro:IPR018385" /db_xref="SubtiList:BG11999" /db_xref="UniProtKB/Swiss-Prot:P55908" /translation="MSMPAAETQPKKKRMTFKMPDAYVLLFMIAFICAIASYIVPAGE FDRVTKGDVTTAVPGSYHSIEQSPVRLISFFTSLQDGMVGSAPIIFLILFTGGTIAIL EKTGAINGLIYNVISKFRTKQLLFICIVGALFSILGTTGIVVNSVIGFIPIGLIVARS LKWDAVAGAAVIYIGCYAGFNSTILSPSPLGLSQSIAELPLFSGIGLRVVIYICFLLS SIIYIYLYTRKLKKSKDASVLGTDWFPAAGMGEAGKEEDQSVPFTVRHKLILAVAGLS LVGFLYGALKLGWSDSQMAATFIFISVLAGLIGGLAANDIAKTFITGCQSLVYGALIV GMARSISVILENGKLLDTVVNALASLLDGFSPIAGAIGMYIASALLHFLISSGSGEAV VFIPILAPLADLMGITRQVAVEAVMLGEGVVNCVNPTSGVLMAVLAASGIPYVKWLRF MVPLALIWFLIGLVFIVIGVMINWGPF*" gene 325339..326772 /gene="ycgA" /locus_tag="BSU_03020" /old_locus_tag="BSU03020" promotor_-35 326077..326085 /Source="Nicolas_upshift_promotors" /id="U218" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.98901098901099" /psig="0.98901098901099" /xcortree=498 /SigmaFactorBS="ggaacagattggttccctgcgGCAGGAATGggcgaagccggT AAAGAAGAAGATCAGTCAgtgccgtttaccgttcgccataagctgattttggctgtgg c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 326097..326115 /Source="Nicolas_upshift_promotors" /id="U218" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.98901098901099" /psig="0.98901098901099" /xcortree=498 /SigmaFactorBS="ggaacagattggttccctgcgGCAGGAATGggcgaagccggT AAAGAAGAAGATCAGTCAgtgccgtttaccgttcgccataagctgattttggctgtgg c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 326116 /Source="Nicolas_upshifts" /id="U218" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.98901098901099" /psig="0.98901098901099" /xcortree=498 /SigmaFactorBS="ggaacagattggttccctgcgGCAGGAATGggcgaagccggT AAAGAAGAAGATCAGTCAgtgccgtttaccgttcgccataagctgattttggctgtgg c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" downshifts 326754 /Source="Nicolas_upshifts" /id="D130" /incds=0 /nref=1 /ntot=74 /MaxReadThrough="3.53497" /MaxDrop="3.31444" /score="12.0135493" /energy="-15.6" /TU="U217" /idTUdmin="U218" /TUdmin=0 /isTUend="TRUE" promotor_-35 326815..326822 /Source="Nicolas_upshift_promotors" /id="U219" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.915084915084915" /psig="0.999000999001" /xcortree=1929 /SigmaFactorBS="ccggcttgtacggcgggcttttgagttatTCATTGCAgaagc gcaggctgtTATTGTAACATGTAAGCCATaagccattcgtaaaagtgcgggaggaagg t" /listShort="ycgB, S108, amyE" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 326837..326856 /Source="Nicolas_upshift_promotors" /id="U219" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.915084915084915" /psig="0.999000999001" /xcortree=1929 /SigmaFactorBS="ccggcttgtacggcgggcttttgagttatTCATTGCAgaagc gcaggctgtTATTGTAACATGTAAGCCATaagccattcgtaaaagtgcgggaggaagg t" /listShort="ycgB, S108, amyE" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 326846 /Source="Nicolas_upshifts" /id="U219" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.915084915084915" /psig="0.999000999001" /xcortree=1929 /SigmaFactorBS="ccggcttgtacggcgggcttttgagttatTCATTGCAgaagc gcaggctgtTATTGTAACATGTAAGCCATaagccattcgtaaaagtgcgggaggaagg t" /listShort="ycgB, S108, amyE" /GFF_Attribute="listLong" CDS 326888..327469 /gene="ycgB" /locus_tag="BSU_03030" /old_locus_tag="BSU03030" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 15849754, 16850406, 22720735; Producttype m: membrane component" /codon_start=1 /transl_table=11 /product="putative integral inner membrane protein of unknown function" /protein_id="NP_388185.2" /db_xref="EnsemblGenomes-Gn:BSU03030" /db_xref="EnsemblGenomes-Tr:CAB12097" /db_xref="SubtiList:BG12000" /db_xref="UniProtKB/Swiss-Prot:P55909" /translation="MNNLRNRLSGVNGKNKRVKEKEQKIWSEIGMIAGAFALLDVIIR GIMFEFPFKEWAASLVFLFIIILYYCIRAAASGMLMPRIDTKEELQKRVKQQRIESIA VAFAVVVLTMYDRGIPHTFFAWLKMILLFIVCGGVLFLLRYVIVKLAYRRAVKEEIKK KSSFLFGKRGKRSQFRAAFFIGTLICIHSAKLF*" gene 326888..327469 /gene="ycgB" /locus_tag="BSU_03030" /old_locus_tag="BSU03030" upshifts 327282 /Source="Nicolas_upshifts" /id="U220" /multdbtbs="-" /comp="M21" /sig="Sig-" /pcomp="0.288711288711289" /psig="0.241758241758242" /xcortree=1550 /SigmaFactorBS="tgtacgacagggggattccccatacattcttcgcttggctga aaatgattcttctttttatcgtCTGCGgcggcgttctgtttctgcttcggtatgtgat t" /listShort="S108, amyE" /GFF_Attribute="listLong" misc_feature 327286..327290 /Source="Nicolas_upshift_promotors" /id="U220" /multdbtbs="-" /comp="M21" /sig="Sig-" /pcomp="0.288711288711289" /psig="0.241758241758242" /xcortree=1550 /SigmaFactorBS="tgtacgacagggggattccccatacattcttcgcttggctga aaatgattcttctttttatcgtCTGCGgcggcgttctgtttctgcttcggtatgtgat t" /listShort="S108, amyE" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" promotor_-35 327445..327452 /Source="Nicolas_upshift_promotors" /id="U221" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.892107892107892" /psig="0.999000999001" /xcortree=365 /SigmaFactorBS="ctttttttataggaacattgatttgTATTCACTctgccaagt tgtttTGATAGAGTGATTGTGATAAttttaaatgtaagcgttaacaaaattctccagt c" /listShort="S108, amyE" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 327467..327486 /Source="Nicolas_upshift_promotors" /id="U221" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.892107892107892" /psig="0.999000999001" /xcortree=365 /SigmaFactorBS="ctttttttataggaacattgatttgTATTCACTctgccaagt tgtttTGATAGAGTGATTGTGATAAttttaaatgtaagcgttaacaaaattctccagt c" /listShort="S108, amyE" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 327480..327617 /Source="Nicolas_S_feature" /locus_tag="new_327480_327617" /HighExp="BC, M0t90, M40t90, S2, M9-stat, T4.0H, Sw, T3.30H, Lbtran, T3.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, Sig-, SigA" /TUshortPSig="0.999, 0.242, 0.999" /TUlongSig="SigA" /TUlongPSig="0.999" /label="S108" upshifts 327480 /Source="Nicolas_upshifts" /id="U221" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.892107892107892" /psig="0.999000999001" /xcortree=365 /SigmaFactorBS="ctttttttataggaacattgatttgTATTCACTctgccaagt tgtttTGATAGAGTGATTGTGATAAttttaaatgtaagcgttaacaaaattctccagt c" /listShort="S108, amyE" /GFF_Attribute="listLong" CDS 327618..329597 /gene="amyE" /locus_tag="BSU_03040" /old_locus_tag="BSU03040" /EC_number="3.2.1.1" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:3117969, 9353930" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 3117969, 9353930; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="alpha-amylase" /protein_id="NP_388186.2" /db_xref="EnsemblGenomes-Gn:BSU03040" /db_xref="EnsemblGenomes-Tr:CAB12098" /db_xref="GOA:P00691" /db_xref="InterPro:IPR006046" /db_xref="InterPro:IPR006047" /db_xref="InterPro:IPR013783" /db_xref="InterPro:IPR017853" /db_xref="InterPro:IPR031319" /db_xref="InterPro:IPR031965" /db_xref="PDB:1BAG" /db_xref="PDB:1UA7" /db_xref="SubtiList:BG10473" /db_xref="UniProtKB/Swiss-Prot:P00691" /translation="MFAKRFKTSLLPLFAGFLLLFHLVLAGPAAASAETANKSNELTA PSIKSGTILHAWNWSFNTLKHNMKDIHDAGYTAIQTSPINQVKEGNQGDKSMSNWYWL YQPTSYQIGNRYLGTEQEFKEMCAAAEEYGIKVIVDAVINHTTSDYAAISNEVKSIPN WTHGNTQIKNWSDRWDVTQNSLLGLYDWNTQNTQVQSYLKRFLDRALNDGADGFRFDA AKHIELPDDGSYGSQFWPNITNTSAEFQYGEILQDSASRDAAYANYMDVTASNYGHSI RSALKNRNLGVSNISHYASDVSADKLVTWVESHDTYANDDEESTWMSDDDIRLGWAVI ASRSGSTPLFFSRPEGGGNGVRFPGKSQIGDRGSALFEDQAITAVNRFHNVMAGQPEE LSNPNGNNQIFMNQRGSHGVVLANAGSSSVSINTATKLPDGRYDNKAGAGSFQVNDGK LTGTINARSVAVLYPDDIAKAPHVFLENYKTGVTHSFNDQLTITLRADANTTKAVYQI NNGPETAFKDGDQFTIGKGDPFGKTYTIMLKGTNSDGVTRTEKYSFVKRDPASAKTIG YQNPNHWSQVNAYIYKHDGSRVIELTGSWPGKPMTKNADGIYTLTLPADTDTTNAKVI FNNGSAQVPGQNQPGFDYVLNGLYNDSGLSGSLPH*" gene 327618..329597 /gene="amyE" /locus_tag="BSU_03040" /old_locus_tag="BSU03040" downshifts 329611 /Source="Nicolas_upshifts" /id="D131" /incds=0 /nref=57 /ntot=131 /MaxReadThrough="1.64783" /MaxDrop="6.55823" /score="-8.82332571" /energy="-3.4" /TU="U221" /idTUdmin="U219" /TUdmin=0 /isTUend="TRUE" promotor_-35 329677..329684 /Source="Nicolas_upshift_promotors" /id="U222" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.753246753246753" /psig=1 /xcortree=1599 /SigmaFactorBS="caatgatggtttcttttttgttcataaatcagacaaaacttt tCTCTTGCAaaagtttgtgaagTGTTGCACAATATAAATGTGaaatacttcacaaaca a" /listShort="ldh, lctP" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 329694 /Source="Nicolas_upshifts" /id="U222" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.753246753246753" /psig=1 /xcortree=1599 /SigmaFactorBS="caatgatggtttcttttttgttcataaatcagacaaaacttt tCTCTTGCAaaagtttgtgaagTGTTGCACAATATAAATGTGaaatacttcacaaaca a" /listShort="ldh, lctP" /GFF_Attribute="listLong" promotor_-10 329698..329717 /Source="Nicolas_upshift_promotors" /id="U222" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.753246753246753" /psig=1 /xcortree=1599 /SigmaFactorBS="caatgatggtttcttttttgttcataaatcagacaaaacttt tCTCTTGCAaaagtttgtgaagTGTTGCACAATATAAATGTGaaatacttcacaaaca a" /listShort="ldh, lctP" /GFF_Attribute="listLong" /label="promotor_-10" CDS 329774..330739 /gene="lctE" /locus_tag="BSU_03050" /old_locus_tag="BSU03050" /EC_number="1.1.1.27" /function="16.10: Respire" /experiment="publication(s) with functional evidences, PMID:10809684, 16207915, 19383131" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10809684, 16207915, 19383131; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="L-lactate dehydrogenase" /protein_id="NP_388187.2" /db_xref="EnsemblGenomes-Gn:BSU03050" /db_xref="EnsemblGenomes-Tr:CAB12099" /db_xref="GOA:P13714" /db_xref="InterPro:IPR001236" /db_xref="InterPro:IPR001557" /db_xref="InterPro:IPR011304" /db_xref="InterPro:IPR015955" /db_xref="InterPro:IPR018177" /db_xref="InterPro:IPR022383" /db_xref="InterPro:IPR036291" /db_xref="PDB:3PQD" /db_xref="PDB:3PQE" /db_xref="PDB:3PQF" /db_xref="SubtiList:BG19003" /db_xref="UniProtKB/Swiss-Prot:P13714" /translation="MMNKHVNKVALIGAGFVGSSYAFALINQGITDELVVIDVNKEKA MGDVMDLNHGKAFAPQPVKTSYGTYEDCKDADIVCICAGANQKPGETRLELVEKNLKI FKGIVSEVMASGFDGIFLVATNPVDILTYATWKFSGLPKERVIGSGTTLDSARFRFML SEYFGAAPQNVHAHIIGEHGDTELPVWSHANVGGVPVSELVEKNDAYKQEELDQIVDD VKNAAYHIIEKKGATYYGVAMSLARITKAILHNENSILTVSTYLDGQYGADDVYIGVP AVVNRGGIAGITELNLNEKEKEQFLHSAGVLKNILKPHFAEQKVN*" gene 329774..330739 /gene="lctE" /locus_tag="BSU_03050" /old_locus_tag="BSU03050" CDS 330771..332396 /gene="lctP" /locus_tag="BSU_03060" /old_locus_tag="BSU03060" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:10809684, 15849754, 16428414, 16850406" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10809684, 15849754, 16428414, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="L-lactate permease" /protein_id="NP_388188.2" /db_xref="EnsemblGenomes-Gn:BSU03060" /db_xref="EnsemblGenomes-Tr:CAB12100" /db_xref="GOA:P55910" /db_xref="InterPro:IPR003804" /db_xref="SubtiList:BG12001" /db_xref="UniProtKB/Swiss-Prot:P55910" /translation="MWEQLYDPFGNEYVSALVALTPILFFLLALTVLKMKGILAAFLT LAVSFFVSVWAFHMPVEKAISSVLLGIGSGLWPIGYIVLMAVWLYKIAVKTGKFTIIR SSIAGISPDQRLQLLLIGFCFNAFLEGAAGFGVPIAISAALLVELGFKPLKAAALCLI ANAASGAFGAIGIPVITGAQIGDLSALELSRTLMWTLPMISFLIPFLLVFLLDRMKGI KQTWPALLVVSGGYTAVQTLTMAVLGPELANILAALFSMGGLALFLRKWQPKEIYREE GAGDAGEKKAYRAADIAKAWSPFYILTAAITIWSLPAFKALFQEGGLLYQSTLLFKMP FLHQQIMKMPPIAPSAMPLDAVFKVDLLSATGTAILAAVIVTGLFSKKFSSRDAFASL KETGKELWVPIMTICFVMGFANLANFAGLSSSIGLALAKTGDLFPFVSPVLGWIGVFI TGSVVSNNALFGHLQVVTGAQIGAGSDLLLAANTAGGVMAKLVSPQSIAIAAAAVGQT GKESKLFKRTVAYSLILLLIICIWTFILARLGV*" gene 330771..332396 /gene="lctP" /locus_tag="BSU_03060" /old_locus_tag="BSU03060" downshifts 330777 /Source="Nicolas_upshifts" /id="D132" /incds=0 /nref=1 /ntot=16 /MaxReadThrough="8.56142" /MaxDrop="2.8862" /score="-8.82332571" /energy="-3.4" /TU="U222" /idTUdmin="U221" /TUdmin=1144 /isTUend="FALSE" downshifts 332383 /Source="Nicolas_upshifts" /id="D133" /incds=0 /nref=51 /ntot=118 /MaxReadThrough="2.31168" /MaxDrop="7.73065" /score="39.575264" /energy="-15.6" /TU="NA" /idTUdmin="U222" /TUdmin=0 /isTUend="TRUE" CDS complement(332441..333979) /gene="mdr" /locus_tag="BSU_03070" /old_locus_tag="BSU03070" /function="16.1: Circulate" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:9023234, 15489457, 15849754, 16850406, 21690368" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9023234, 15489457, 15849754, 16850406, 21690368; Product type t : transporter" /codon_start=1 /transl_table=11 /product="multidrug-efflux transporter" /protein_id="NP_388189.2" /db_xref="EnsemblGenomes-Gn:BSU03070" /db_xref="EnsemblGenomes-Tr:CAB12101" /db_xref="GOA:P96712" /db_xref="InterPro:IPR004638" /db_xref="InterPro:IPR011701" /db_xref="InterPro:IPR020846" /db_xref="InterPro:IPR036259" /db_xref="SubtiList:BG12002" /db_xref="UniProtKB/Swiss-Prot:P96712" /translation="MDTTTAKQASTKFVVLGLLLGILMSAMDNTIVATAMGNIVADLG SFDKFAWVTASYMVAVMAGMPIYGKLSDMYGRKRFFLFGLIFFLIGSALCGIAQTMNQ LIIFRAIQGIGGGALLPIAFTIIFDLFPPEKRGKMSGMFGAVFGLSSVLGPLLGAIIT DSISWHWVFYINVPIGALSLFFIIRYYKESLEHRKQKIDWGGAITLVVSIVCLMFALE LGGKTYDWNSIQIIGLFIVFAVFFIAFFIVERKAEEPIISFWMFKNRLFATAQILAFL YGGTFIILAVFIPIFVQAVYGSSATSAGFILTPMMIGSVIGSMIGGIFQTKASFRNLM LISVIAFFIGMLLLSNMTPDTARVWLTVFMMISGFGVGFNFSLLPAASMNDLEPRFRG TANSTNSFLRSFGMTLGVTIFGTVQTNVFTNKLNDAFSGMKGSAGSGAAQNIGDPQEI FQAGTRSQIPDAILNRIIDAMSSSITYVFLLALIPIVLAAVTILFMGKARVKTTAEMT KKAN*" gene complement(332441..333979) /gene="mdr" /locus_tag="BSU_03070" /old_locus_tag="BSU03070" downshifts complement(332459) /Source="Nicolas_upshifts" /id="D134" /incds=0 /nref=70 /ntot=182 /MaxReadThrough="1.04964" /MaxDrop="4.53635" /score="30.8374042" /energy="-15.6" /TU="NA" /idTUdmin="U225" /TUdmin=0 /isTUend="TRUE" promotor_no_box complement(333033..333133) /Source="Nicolas_upshift_promotors" /id="U223" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.495504495504495" /psig="0.002997002997003" /xcortree=1728 /SigmaFactorBS="attttagcggtatttattccgattttcgttcaggcggtctac ggcagctcggcgacaagcgcgggcttcattctgacgccgatgatgattggatcagtca t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_no_box" upshifts complement(333073) /Source="Nicolas_upshifts" /id="U223" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.495504495504495" /psig="0.002997002997003" /xcortree=1728 /SigmaFactorBS="attttagcggtatttattccgattttcgttcaggcggtctac ggcagctcggcgacaagcgcgggcttcattctgacgccgatgatgattggatcagtca t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 333993..333997 /Source="Nicolas_upshift_promotors" /id="U224" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.772227772227772" /psig="0.971028971028971" /xcortree=2583 /SigmaFactorBS="ttgttgtgtccatttgttctacctccTCTTActtttctatgt aagtTCTGATATCATGATAATAGTttgattgttgaatatctcgattatcaagataaac t" /listShort="ycgE, ycgF, ycgG" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 334013..334032 /Source="Nicolas_upshift_promotors" /id="U224" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.772227772227772" /psig="0.971028971028971" /xcortree=2583 /SigmaFactorBS="ttgttgtgtccatttgttctacctccTCTTActtttctatgt aagtTCTGATATCATGATAATAGTttgattgttgaatatctcgattatcaagataaac t" /listShort="ycgE, ycgF, ycgG" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 334027 /Source="Nicolas_upshifts" /id="U224" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.772227772227772" /psig="0.971028971028971" /xcortree=2583 /SigmaFactorBS="ttgttgtgtccatttgttctacctccTCTTActtttctatgt aagtTCTGATATCATGATAATAGTttgattgttgaatatctcgattatcaagataaac t" /listShort="ycgE, ycgF, ycgG" /GFF_Attribute="listLong" promotor_-10 complement(334059..334078) /Source="Nicolas_upshift_promotors" /id="U225" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.501498501498502" /psig="0.999000999001" /xcortree=2540 /SigmaFactorBS="ccaactcacttctggaatttcttGTTGACAactgacagtcct ccCTATAAAATCGAGTTTATCTtgataatcgagatattcaacaatcaaactattatca t" /listShort="mdr" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(334062) /Source="Nicolas_upshifts" /id="U225" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.501498501498502" /psig="0.999000999001" /xcortree=2540 /SigmaFactorBS="ccaactcacttctggaatttcttGTTGACAactgacagtcct ccCTATAAAATCGAGTTTATCTtgataatcgagatattcaacaatcaaactattatca t" /listShort="mdr" /GFF_Attribute="listLong" CDS 334092..334556 /gene="ycgE" /locus_tag="BSU_03080" /old_locus_tag="BSU03080" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative transcriptional regulator" /protein_id="NP_388190.2" /db_xref="EnsemblGenomes-Gn:BSU03080" /db_xref="EnsemblGenomes-Tr:CAB12102" /db_xref="GOA:O31472" /db_xref="InterPro:IPR000835" /db_xref="InterPro:IPR011991" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG12003" /db_xref="UniProtKB/Swiss-Prot:O31472" /translation="MSTRNSRSELEKTAVQLFRKLGTRTVLFHQAAAQALGLFPTDLK SADILNEAGPMTAGELGKKTGLSTGSVTALVDRLEKAGYVAREKDPNDRRRVVIVPLT ASKKHIKDLFRPLSESTMDLCREYTEEELELIFSFVGKAADIMEEELERLKQ*" gene 334092..334556 /gene="ycgE" /locus_tag="BSU_03080" /old_locus_tag="BSU03080" promotor_-35 complement(334093..334099) /Source="Nicolas_upshift_promotors" /id="U225" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.501498501498502" /psig="0.999000999001" /xcortree=2540 /SigmaFactorBS="ccaactcacttctggaatttcttGTTGACAactgacagtcct ccCTATAAAATCGAGTTTATCTtgataatcgagatattcaacaatcaaactattatca t" /listShort="mdr" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 334566..334571 /Source="Nicolas_upshift_promotors" /id="U226" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=970 /SigmaFactorBS="ttgaacgtctgaaacagtaagtgaatttgTGCATAgcttggc ccgttcccGAATAAATTGTACAAGTTAcataagagaagggagtacgggccggtgaaca t" /listShort="ycgF, ycgG" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 334587..334605 /Source="Nicolas_upshift_promotors" /id="U226" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=970 /SigmaFactorBS="ttgaacgtctgaaacagtaagtgaatttgTGCATAgcttggc ccgttcccGAATAAATTGTACAAGTTAcataagagaagggagtacgggccggtgaaca t" /listShort="ycgF, ycgG" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 334597 /Source="Nicolas_upshifts" /id="U226" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=970 /SigmaFactorBS="ttgaacgtctgaaacagtaagtgaatttgTGCATAgcttggc ccgttcccGAATAAATTGTACAAGTTAcataagagaagggagtacgggccggtgaaca t" /listShort="ycgF, ycgG" /GFF_Attribute="listLong" CDS 334630..335259 /gene="ycgF" /locus_tag="BSU_03090" /old_locus_tag="BSU03090" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative aminoacid export permease" /protein_id="NP_388191.1" /db_xref="EnsemblGenomes-Gn:BSU03090" /db_xref="EnsemblGenomes-Tr:CAB12103" /db_xref="GOA:P94381" /db_xref="InterPro:IPR001123" /db_xref="SubtiList:BG12004" /db_xref="UniProtKB/Swiss-Prot:P94381" /translation="MNIFLSYIVLGLSLSAPVGPVNAAQIDKGIKNGFWHAWIFGLGA MTADGLYMLFIYFGLSQFLTAPFVKTFLWLFGFFVLTYTGIETLKNVREPMDVRSSRG KPSYRKTFASGFLISLSNPLSILFWLGIYGSILAKTAEAYNMNQLLIYSSGIMIGILI WDFCMAITASTFRNLLHEKLLRGLTGIAGVSLLVFGFYFGYQGIKQLLG*" gene 334630..335259 /gene="ycgF" /locus_tag="BSU_03090" /old_locus_tag="BSU03090" promotor_-35 335270..335279 /Source="Nicolas_upshift_promotors" /id="U227" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=1281 /SigmaFactorBS="caaacagttattgggctgattcatgaaggACAGTCACCTgcc gcttccagttTTAATATAGTATCCAGATGAtactggaggtggatcaatggtgaatggg a" /listShort="ycgG" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 335293..335312 /Source="Nicolas_upshift_promotors" /id="U227" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=1281 /SigmaFactorBS="caaacagttattgggctgattcatgaaggACAGTCACCTgcc gcttccagttTTAATATAGTATCCAGATGAtactggaggtggatcaatggtgaatggg a" /listShort="ycgG" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 335301 /Source="Nicolas_upshifts" /id="U227" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=1281 /SigmaFactorBS="caaacagttattgggctgattcatgaaggACAGTCACCTgcc gcttccagttTTAATATAGTATCCAGATGAtactggaggtggatcaatggtgaatggg a" /listShort="ycgG" /GFF_Attribute="listLong" CDS 335329..336090 /gene="ycgG" /locus_tag="BSU_03100" /old_locus_tag="BSU03100" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function (similar to phage protein)" /protein_id="NP_388192.2" /db_xref="EnsemblGenomes-Gn:BSU03100" /db_xref="EnsemblGenomes-Tr:CAB12104" /db_xref="InterPro:IPR014988" /db_xref="SubtiList:BG12005" /db_xref="UniProtKB/Swiss-Prot:P94382" /translation="MVNGIYTKSFLERIQEELPEWQRIAFELLAETLGDDADTFPCIP GRQAFLTDQLRIAFAGDPRENRTAEELAPLLAEYGKISRDTGKYASLVVLFDTPEDLA EHYSIEAYEELFWRFLNRLSHQDEKEWPEDIPADPEHYKWEFCFDGEPYFILCATPGH EARRSRSFPFFMVTFQPRWVFDDLNGSTAFGRNMSRLIRSRLEAYDQAPIHPQLGWYG GKDNREWKQYFLRDDEKQVSKCPFSYLKNMFNKMK*" gene 335329..336090 /gene="ycgG" /locus_tag="BSU_03100" /old_locus_tag="BSU03100" S_feature complement(335729..336091) /Source="Nicolas_S_feature" /locus_tag="new_335729_336091_c" /HighExp="S8, S7, S5, S6, S4, nit, ferm, BT, Pyr, G/S" /AntisenseName="ycgG" /AntisenseCor="0.73875580854115197" /AntisenseRegPval="-46.9" /CDS_PredictionProba="NA" /TUshortSig="SigGF" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S109" downshifts 336087 /Source="Nicolas_upshifts" /id="D135" /incds=0 /nref=21 /ntot=174 /MaxReadThrough="1.53211" /MaxDrop="4.92685" /score="6.36985882" /energy="-8.6" /TU="NA" /idTUdmin="U227" /TUdmin="-6" /isTUend="TRUE" CDS complement(336092..337432) /gene="ycgH" /locus_tag="BSU_03110" /old_locus_tag="BSU03110" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative amino acid transporter" /protein_id="NP_388193.2" /db_xref="EnsemblGenomes-Gn:BSU03110" /db_xref="EnsemblGenomes-Tr:CAB12105" /db_xref="GOA:P94383" /db_xref="InterPro:IPR002293" /db_xref="InterPro:IPR004841" /db_xref="SubtiList:BG12006" /db_xref="UniProtKB/Swiss-Prot:P94383" /translation="MSQTKKDQPKGNLAWWQLSLIGVGCTIGTGFFLGSSIAIVKSGF SVLLSFLIAGIGTYFVFEQLAKLSAKQPEKGSFCAYARKAFGKWAGFSNGWVYWTSEM LITGSQLTAISLFTKHWFPQVPLWVFASIYAVLGLLIIFTGLSVFEKTENVLAVIKTA AIFMFIVIAILALCGILSGGNHGIHVPNKTSEFFPYGAMGLWTGLIYAFYAFGGIEVM GLMAVHLKKPEEASKSGKLMLATLAIIYIISIGLALLLVPLHTFTEQDSPFITSLKGY NLEIILDIFNGIFIIAGFSTLVASLFAVTTLLCTMADDGDAPKCFTLKEGKKICWPAL GLTFAGLVLSIILSLVLPKNIYEHMTTAAGLMLLYTWLFILFSSKKLTDPEGMGKTQI YLAMVLIAAAVSGTLFEKSSRPGFFVSIGFLVIIAIVTMIYQKKQGHKDRPASP*" gene complement(336092..337432) /gene="ycgH" /locus_tag="BSU_03110" /old_locus_tag="BSU03110" promotor_-10 complement(337459..337470) /Source="Nicolas_upshift_promotors" /id="U228" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=918 /SigmaFactorBS="ctgcttccttctccatgtaaaaagaggcaaaaatccgaTGTA TATaagctttggacagaTCACAATCTAACcttagataaaaggggttgaataaataatg a" /listShort="ycgH, S109" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(337469) /Source="Nicolas_upshifts" /id="U228" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=918 /SigmaFactorBS="ctgcttccttctccatgtaaaaagaggcaaaaatccgaTGTA TATaagctttggacagaTCACAATCTAACcttagataaaaggggttgaataaataatg a" /listShort="ycgH, S109" /GFF_Attribute="listLong" promotor_-35 complement(337485..337491) /Source="Nicolas_upshift_promotors" /id="U228" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=918 /SigmaFactorBS="ctgcttccttctccatgtaaaaagaggcaaaaatccgaTGTA TATaagctttggacagaTCACAATCTAACcttagataaaaggggttgaataaataatg a" /listShort="ycgH, S109" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 337511..337517 /Source="Nicolas_upshift_promotors" /id="U229" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=817 /SigmaFactorBS="ttgtgatctgtccaaagcttatatacatcggatttttgcctc ttttTACATGGagaaggaagcagacGCTCATACTAATgaaaaaaggagcaaaccaatg a" /listShort="ycgI" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 337525 /Source="Nicolas_upshifts" /id="U229" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=817 /SigmaFactorBS="ttgtgatctgtccaaagcttatatacatcggatttttgcctc ttttTACATGGagaaggaagcagacGCTCATACTAATgaaaaaaggagcaaaccaatg a" /listShort="ycgI" /GFF_Attribute="listLong" promotor_-10 337532..337543 /Source="Nicolas_upshift_promotors" /id="U229" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=817 /SigmaFactorBS="ttgtgatctgtccaaagcttatatacatcggatttttgcctc ttttTACATGGagaaggaagcagacGCTCATACTAATgaaaaaaggagcaaaccaatg a" /listShort="ycgI" /GFF_Attribute="listLong" /label="promotor_-10" CDS 337562..338158 /gene="ycgI" /locus_tag="BSU_03120" /old_locus_tag="BSU03120" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1b: Function from experimental evidences in the studied species; PubMedId: 16433904, 28898812; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="xenotiotic metabolite methyltransferase" /protein_id="NP_388194.3" /db_xref="EnsemblGenomes-Gn:BSU03120" /db_xref="EnsemblGenomes-Tr:CAB12106" /db_xref="InterPro:IPR018959" /db_xref="SubtiList:BG12007" /db_xref="UniProtKB/Swiss-Prot:O31473" /translation="MTQQYIVEPKKGLGLKLKKGQILKVVDVEGQQVADFVAYHAKDF YEHLDQGATIDANHSIHVKVNDHLYSNLYKPMLTLIEDTVGKHDLLLPACRPDMNRLL YGKQKDEFQDTCYDNMNRALEQFGVPKPHMHYPFAIFMNTVLDEKGNLSVETPLSNAG DYVRLRAEMDLIVAFSSCPIEKGKCNGDSVTSIRVEVS*" gene 337562..338158 /gene="ycgI" /locus_tag="BSU_03120" /old_locus_tag="BSU03120" promotor_-35 338166..338173 /Source="Nicolas_upshift_promotors" /id="U230" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.471528471528472" /psig="0.99100899100899" /xcortree=104 /SigmaFactorBS="gtgtgacatccatacgggttgaagtcagctgatctctctTGT TCACAgtgaatgaagaccTGTGCTATATTTAATAGGGAtacataacagtcatgattca t" /listShort="S110, nadE" /GFF_Attribute="listLong" /label="promotor_-35" S_feature 338187..338287 /Source="Nicolas_S_feature" /locus_tag="new_338187_338287" /HighExp="dia15, LBGtran, dia5, Etha, dia0, LBGexp, M0t45, Lbexp, Diami, Heat" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.991" /TUlongSig="NA" /TUlongPSig="NA" /label="S110" promotor_-10 338187..338206 /Source="Nicolas_upshift_promotors" /id="U230" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.471528471528472" /psig="0.99100899100899" /xcortree=104 /SigmaFactorBS="gtgtgacatccatacgggttgaagtcagctgatctctctTGT TCACAgtgaatgaagaccTGTGCTATATTTAATAGGGAtacataacagtcatgattca t" /listShort="S110, nadE" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 338187 /Source="Nicolas_upshifts" /id="U230" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.471528471528472" /psig="0.99100899100899" /xcortree=104 /SigmaFactorBS="gtgtgacatccatacgggttgaagtcagctgatctctctTGT TCACAgtgaatgaagaccTGTGCTATATTTAATAGGGAtacataacagtcatgattca t" /listShort="S110, nadE" /GFF_Attribute="listLong" downshifts complement(338283) /Source="Nicolas_upshifts" /id="D136" /incds=0 /nref=3 /ntot=24 /MaxReadThrough="1.2989" /MaxDrop="4.67402" /score="15.0992897" /energy="-14.1" /TU="NA" /idTUdmin="U233" /TUdmin=1562 /isTUend="FALSE" CDS 338288..339106 /gene="nadE" /locus_tag="BSU_03130" /old_locus_tag="BSU03130" /EC_number="6.3.1.5" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:7890752, 9271869, 12682299, 19204287" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7890752, 9271869, 12682299, 19204287; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="ammonium-dependent NAD+ synthetase" /protein_id="NP_388195.1" /db_xref="EnsemblGenomes-Gn:BSU03130" /db_xref="EnsemblGenomes-Tr:CAB12107" /db_xref="GOA:P08164" /db_xref="InterPro:IPR003694" /db_xref="InterPro:IPR014729" /db_xref="InterPro:IPR022310" /db_xref="InterPro:IPR022926" /db_xref="PDB:1EE1" /db_xref="PDB:1FYD" /db_xref="PDB:1IFX" /db_xref="PDB:1IH8" /db_xref="PDB:1KQP" /db_xref="PDB:1NSY" /db_xref="PDB:2NSY" /db_xref="SubtiList:BG10694" /db_xref="UniProtKB/Swiss-Prot:P08164" /translation="MSMQEKIMRELHVKPSIDPKQEIEDRVNFLKQYVKKTGAKGFVL GISGGQDSTLAGRLAQLAVESIREEGGDAQFIAVRLPHGTQQDEDDAQLALKFIKPDK SWKFDIKSTVSAFSDQYQQETGDQLTDFNKGNVKARTRMIAQYAIGGQEGLLVLGTDH AAEAVTGFFTKYGDGGADLLPLTGLTKRQGRTLLKELGAPERLYLKEPTADLLDEKPQ QSDETELGISYDEIDDYLEGKEVSAKVSEALEKRYSMTEHKRQVPASMFDDWWK*" gene 338288..339106 /gene="nadE" /locus_tag="BSU_03130" /old_locus_tag="BSU03130" downshifts 339088 /Source="Nicolas_upshifts" /id="D137" /incds=0 /nref=144 /ntot=271 /MaxReadThrough="2.68866" /MaxDrop="6.24927" /score="20.6612287" /energy="-14.1" /TU="U230" /idTUdmin="U230" /TUdmin="-65" /isTUend="FALSE" CDS complement(339156..339749) /gene="tmrB" /locus_tag="BSU_03140" /old_locus_tag="BSU03140" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:1624425, 7766032, 15131133, 27315722" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1624425, 7766032, 15131133, 27315722; Product type f: factor" /codon_start=1 /transl_table=11 /product="ATP-binding tunicamycin resistance protein" /protein_id="NP_388196.2" /db_xref="EnsemblGenomes-Gn:BSU03140" /db_xref="EnsemblGenomes-Tr:CAB12108" /db_xref="GOA:P12921" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG10456" /db_xref="UniProtKB/Swiss-Prot:P12921" /translation="MIIWINGAFGSGKTQTAFELHRRLNPSYVYDPEKMGFALRSMVP QEIAKDDFQSYPLWRAFNYSLLASLTDTYRGILIVPMTIVHPEYFNEIIGRLRQEGRI VHHFTLMASKETLLKRLRTRAEGKNSWAAKQIDRCVEGLSSPIFEDHIQTDNLSIQDV AENIAARAELPLDPDTRGSLRRFADRLMVKLNHIRIK*" gene complement(339156..339749) /gene="tmrB" /locus_tag="BSU_03140" /old_locus_tag="BSU03140" downshifts complement(339163) /Source="Nicolas_upshifts" /id="D138" /incds=0 /nref=10 /ntot=143 /MaxReadThrough="0.60282" /MaxDrop="3.74815" /score="15.0992897" /energy="-14.1" /TU="NA" /idTUdmin="U233" /TUdmin=682 /isTUend="FALSE" promotor_-10 complement(339764..339783) /Source="Nicolas_upshift_promotors" /id="U231" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.779220779220779" /psig="0.999000999001" /xcortree=3131 /SigmaFactorBS="gttaaaaccttccgcctttattgtttttccagctgactCTTC gatggaagggtcttTTTCTGTATGATAAATAGGAagggagaaatggcgatgatcattt g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(339779) /Source="Nicolas_upshifts" /id="U231" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.779220779220779" /psig="0.999000999001" /xcortree=3131 /SigmaFactorBS="gttaaaaccttccgcctttattgtttttccagctgactCTTC gatggaagggtcttTTTCTGTATGATAAATAGGAagggagaaatggcgatgatcattt g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(339798..339801) /Source="Nicolas_upshift_promotors" /id="U231" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.779220779220779" /psig="0.999000999001" /xcortree=3131 /SigmaFactorBS="gttaaaaccttccgcctttattgtttttccagctgactCTTC gatggaagggtcttTTTCTGTATGATAAATAGGAagggagaaatggcgatgatcattt g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" S_feature complement(339807..339955) /Source="Nicolas_S_feature" /locus_tag="new_339807_339955_c" /HighExp="S4, S3, S6, S5, S7, BT, S8, LoTm, T5.0H, B36" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigEF" /TUshortPSig="0.987" /TUlongSig="NA" /TUlongPSig="NA" /label="S111" promotor_-35 339857..339864 /Source="Nicolas_upshift_promotors" /id="U232" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.495504495504495" /psig="0.997002997002997" /xcortree=3017 /SigmaFactorBS="aaaggcggaaggttttaacgcttttttgcgtcgaagTATTAA AAtacctgcagaaaTGTTGTACAATGAATGTCATtcaggcaaaaatggctacaacaaa g" /listShort="S112, aroK" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 339877..339896 /Source="Nicolas_upshift_promotors" /id="U232" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.495504495504495" /psig="0.997002997002997" /xcortree=3017 /SigmaFactorBS="aaaggcggaaggttttaacgcttttttgcgtcgaagTATTAA AAtacctgcagaaaTGTTGTACAATGAATGTCATtcaggcaaaaatggctacaacaaa g" /listShort="S112, aroK" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 339879..339987 /Source="Nicolas_S_feature" /locus_tag="new_339879_339987" /HighExp="Diami, BMM, GM 15, GM 25, GM 120, GM 60, GM 10, G180, GM 45, M9-exp" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.997" /TUlongSig="NA" /TUlongPSig="NA" /label="S112" upshifts 339881 /Source="Nicolas_upshifts" /id="U232" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.495504495504495" /psig="0.997002997002997" /xcortree=3017 /SigmaFactorBS="aaaggcggaaggttttaacgcttttttgcgtcgaagTATTAA AAtacctgcagaaaTGTTGTACAATGAATGTCATtcaggcaaaaatggctacaacaaa g" /listShort="S112, aroK" /GFF_Attribute="listLong" promotor_-10 complement(339949..339967) /Source="Nicolas_upshift_promotors" /id="U233" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.987012987012987" /psig="0.987012987012987" /xcortree=1121 /SigmaFactorBS="tcttcggcgaaatcctcctaaggaatgaaattatataTTCAT TatatgcttatttagcGAATATTTATATAGATACCggctttaccggtcaagcttatag t" /listShort="S111" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 339955..339962 /Source="Nicolas_upshift_promotors" /id="U234" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.943056943056943" /psig="0.988011988011988" /xcortree=1750 /SigmaFactorBS="taagcttgaccggtaaagccggtatcTATATAAAtattcgct aaataaGCATATAATGAATATATAATttcattccttaggaggatttcgccgaagatga a" /listShort="aroK" /GFF_Attribute="listLong" /label="promotor_-35" upshifts complement(339965) /Source="Nicolas_upshifts" /id="U233" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.987012987012987" /psig="0.987012987012987" /xcortree=1121 /SigmaFactorBS="tcttcggcgaaatcctcctaaggaatgaaattatataTTCAT TatatgcttatttagcGAATATTTATATAGATACCggctttaccggtcaagcttatag t" /listShort="S111" /GFF_Attribute="listLong" promotor_-10 339977..339996 /Source="Nicolas_upshift_promotors" /id="U234" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.943056943056943" /psig="0.988011988011988" /xcortree=1750 /SigmaFactorBS="taagcttgaccggtaaagccggtatcTATATAAAtattcgct aaataaGCATATAATGAATATATAATttcattccttaggaggatttcgccgaagatga a" /listShort="aroK" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 complement(339983..339988) /Source="Nicolas_upshift_promotors" /id="U233" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.987012987012987" /psig="0.987012987012987" /xcortree=1121 /SigmaFactorBS="tcttcggcgaaatcctcctaaggaatgaaattatataTTCAT TatatgcttatttagcGAATATTTATATAGATACCggctttaccggtcaagcttatag t" /listShort="S111" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 339989 /Source="Nicolas_upshifts" /id="U234" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.943056943056943" /psig="0.988011988011988" /xcortree=1750 /SigmaFactorBS="taagcttgaccggtaaagccggtatcTATATAAAtattcgct aaataaGCATATAATGAATATATAATttcattccttaggaggatttcgccgaagatga a" /listShort="aroK" /GFF_Attribute="listLong" CDS 340025..340585 /gene="aroK" /locus_tag="BSU_03150" /old_locus_tag="BSU03150" /EC_number="2.7.1.71" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 170268, 7612934, 27339308; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="shikimate kinase" /protein_id="NP_388197.2" /db_xref="EnsemblGenomes-Gn:BSU03150" /db_xref="EnsemblGenomes-Tr:CAB12109" /db_xref="GOA:P37944" /db_xref="InterPro:IPR000623" /db_xref="InterPro:IPR023000" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR031322" /db_xref="SubtiList:BG10457" /db_xref="UniProtKB/Swiss-Prot:P37944" /translation="MNAKRAIPVRERNIVLIGFMGVGKTTIGQLVAKKLYRDFIDIDQ QIEKDFNMSIPEIFEKKGEDFFRKTEKEYILDICHHKRFKIVSLGGGSFKQEEIRNCC LENCLVLHLDLSWENWKQRADLLIESRPVLHNRSMDEMEQLFNERKVIYDKHNSKVAT DNLSPEEVADYIVETLKIGWDLYQPM*" gene 340025..340585 /gene="aroK" /locus_tag="BSU_03150" /old_locus_tag="BSU03150" downshifts 340562 /Source="Nicolas_upshifts" /id="D139" /incds=0 /nref=21 /ntot=239 /MaxReadThrough="2.07607" /MaxDrop="4.67156" /score="44.9099474" /energy="-13.1" /TU="NA" /idTUdmin="U232" /TUdmin=1 /isTUend="TRUE" CDS complement(340613..341374) /gene="ycgJ" /locus_tag="BSU_03160" /old_locus_tag="BSU03160" /EC_number="2.1.1.-" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1b: Function from experimental evidences in the studied species; PubMedId: 28898812; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="xenotiotic metabolite methyltransferase" /protein_id="NP_388198.2" /db_xref="EnsemblGenomes-Gn:BSU03160" /db_xref="EnsemblGenomes-Tr:CAB12110" /db_xref="GOA:O31474" /db_xref="InterPro:IPR013216" /db_xref="InterPro:IPR029063" /db_xref="PDB:1XXL" /db_xref="PDB:2GLU" /db_xref="SubtiList:BG12008" /db_xref="UniProtKB/Swiss-Prot:O31474" /translation="MTNETPFSKNAEMYRDEKVFAEGEDLGLMIKTAECRAEHRVLDI GAGAGHTALAFSPYVQECIGVDATKEMVEVASSFAQEKGVENVRFQQGTAESLPFPDD SFDIITCRYAAHHFSDVRKAVREVARVLKQDGRFLLVDHYAPEDPVLDEFVNHLNRLR DPSHVRESSLSEWQAMFSANQLAYQDIQKWNLPIQYDSWIKRGGTPADREKQIITHLN HASDEARDTFCITLNQNGQPISFCLKAILIQGIKR*" gene complement(340613..341374) /gene="ycgJ" /locus_tag="BSU_03160" /old_locus_tag="BSU03160" downshifts complement(340637) /Source="Nicolas_upshifts" /id="D140" /incds=0 /nref=3 /ntot=55 /MaxReadThrough="0.31391" /MaxDrop="3.85249" /score="18.9843263" /energy="-13.1" /TU="NA" /idTUdmin="U235" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(341406..341425) /Source="Nicolas_upshift_promotors" /id="U235" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.392607392607393" /psig="0.942057942057942" /xcortree=1808 /SigmaFactorBS="acctatcattttcatcatttttatatcTTGGACgaatcataa cagaaATTGCTAACATAATCCATATcatcatttacgaaaagaaggagctggttcaaat g" /listShort="ycgJ" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 341407..341414 /Source="Nicolas_upshift_promotors" /id="U236" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.662337662337662" /psig="0.983016983016983" /xcortree=1867 /SigmaFactorBS="cagctccttcttttcgtaaatgatgaTATGGATTatgttagc aatttcTGTTATGATTCGTCCAAGATataaaaatgatgaaaatgataggttcaaccta t" /listShort="ycgK, S113, cah, S114, ycgL" /GFF_Attribute="listLong" /label="promotor_-35" upshifts complement(341412) /Source="Nicolas_upshifts" /id="U235" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.392607392607393" /psig="0.942057942057942" /xcortree=1808 /SigmaFactorBS="acctatcattttcatcatttttatatcTTGGACgaatcataa cagaaATTGCTAACATAATCCATATcatcatttacgaaaagaaggagctggttcaaat g" /listShort="ycgJ" /GFF_Attribute="listLong" promotor_-10 341429..341448 /Source="Nicolas_upshift_promotors" /id="U236" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.662337662337662" /psig="0.983016983016983" /xcortree=1867 /SigmaFactorBS="cagctccttcttttcgtaaatgatgaTATGGATTatgttagc aatttcTGTTATGATTCGTCCAAGATataaaaatgatgaaaatgataggttcaaccta t" /listShort="ycgK, S113, cah, S114, ycgL" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 complement(341440..341445) /Source="Nicolas_upshift_promotors" /id="U235" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.392607392607393" /psig="0.942057942057942" /xcortree=1808 /SigmaFactorBS="acctatcattttcatcatttttatatcTTGGACgaatcataa cagaaATTGCTAACATAATCCATATcatcatttacgaaaagaaggagctggttcaaat g" /listShort="ycgJ" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 341441 /Source="Nicolas_upshifts" /id="U236" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.662337662337662" /psig="0.983016983016983" /xcortree=1867 /SigmaFactorBS="cagctccttcttttcgtaaatgatgaTATGGATTatgttagc aatttcTGTTATGATTCGTCCAAGATataaaaatgatgaaaatgataggttcaaccta t" /listShort="ycgK, S113, cah, S114, ycgL" /GFF_Attribute="listLong" CDS 341492..342466 /gene="ycgK" /locus_tag="BSU_03170" /old_locus_tag="BSU03170" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 10939241; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative transcriptional regulator (LysR family)" /protein_id="NP_388199.2" /db_xref="EnsemblGenomes-Gn:BSU03170" /db_xref="EnsemblGenomes-Tr:CAB12111" /db_xref="GOA:P94387" /db_xref="InterPro:IPR000847" /db_xref="InterPro:IPR005119" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG12009" /db_xref="UniProtKB/Swiss-Prot:P94387" /translation="MDIKVMEYAAEIARRQSFTKAAEHLHIAQPSLSQQIKKLEAELG LTLFHRSHGSVTLTPHGRRFIEKAEDIIRSRDDLLREMQERSQGIGHKLSIGIPAVTG RYLFPPLLKQFLARYPHVEVQLVEKDPVSLEKMTAKGEVDLSVLSLPIEDERLSITPL LTEPVVLAVPKEKQRWMPPELVALIEKALEEDEGRQPCVPIDMVRNVPFILLKEGFGF RRTVLDLCAESGFKPNAAFKTSHIETAQSLVANGLGVTMAPNMVRRDKDPGVIYLSIQ SAPSRTLVFVFLKNRYVSLTAQAFMELSRESLKQTFDEGCLGNKDENI*" gene 341492..342466 /gene="ycgK" /locus_tag="BSU_03170" /old_locus_tag="BSU03170" S_feature 342467..342537 /Source="Nicolas_S_feature" /locus_tag="new_342467_342537" /HighExp="Diami, dia5, dia15, S1, dia0, C90, LBGexp, Heat, Lbexp, GM 120" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.983" /TUlongSig="NA" /TUlongPSig="NA" /label="S113" CDS 342538..343494 /gene="cah" /locus_tag="BSU_03180" /old_locus_tag="BSU03180" /EC_number="3.1.1.41" /EC_number="3.1.1.72" /function="16.11: Scavenge (Catabolism)" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:12842474, 19837798, 21382014" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12842474, 19837798, 21382014; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="promiscuous acetyl xylan esterase-cephalosporin C deacetylase" /protein_id="NP_388200.1" /db_xref="EnsemblGenomes-Gn:BSU03180" /db_xref="EnsemblGenomes-Tr:CAB12112" /db_xref="GOA:P94388" /db_xref="InterPro:IPR008391" /db_xref="InterPro:IPR029058" /db_xref="PDB:1L7A" /db_xref="PDB:1ODS" /db_xref="PDB:1ODT" /db_xref="SubtiList:BG11919" /db_xref="UniProtKB/Swiss-Prot:P94388" /translation="MQLFDLPLDQLQTYKPEKTAPKDFSEFWKLSLEELAKVQAEPDL QPVDYPADGVKVYRLTYKSFGNARITGWYAVPDKEGPHPAIVKYHGYNASYDGEIHEM VNWALHGYATFGMLVRGQQSSEDTSISPHGHALGWMTKGILDKDTYYYRGVYLDAVRA LEVISSFDEVDETRIGVTGGSQGGGLTIAAAALSDIPKAAVADYPYLSNFERAIDVAL EQPYLEINSFFRRNGSPETEVQAMKTLSYFDIMNLADRVKVPVLMSIGLIDKVTPPST VFAAYNHLETKKELKVYRYFGHEYIPAFQTEKLAFFKQHLKG*" gene 342538..343494 /gene="cah" /locus_tag="BSU_03180" /old_locus_tag="BSU03180" promotor_-35 342953..342959 /Source="Nicolas_upshift_promotors" /id="U237" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=806 /SigmaFactorBS="ttcaccgcacggtcacgctttgggctggatgaCGAAAGGaat tcttgataaagATACATACTATTaccgcggtgtttatttggacgccgtccgcgcgctt g" /listShort="S114, ycgL" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 342974..342985 /Source="Nicolas_upshift_promotors" /id="U237" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=806 /SigmaFactorBS="ttcaccgcacggtcacgctttgggctggatgaCGAAAGGaat tcttgataaagATACATACTATTaccgcggtgtttatttggacgccgtccgcgcgctt g" /listShort="S114, ycgL" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 342981 /Source="Nicolas_upshifts" /id="U237" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=806 /SigmaFactorBS="ttcaccgcacggtcacgctttgggctggatgaCGAAAGGaat tcttgataaagATACATACTATTaccgcggtgtttatttggacgccgtccgcgcgctt g" /listShort="S114, ycgL" /GFF_Attribute="listLong" S_feature 343495..343573 /Source="Nicolas_S_feature" /locus_tag="new_343495_343573" /HighExp="dia5, dia15, Diami, dia0, B36, S1, MG 10, BT, B60, MG t5" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigGF, SigA" /TUshortPSig="0.998, 0.983" /TUlongSig="NA" /TUlongPSig="NA" /label="S114" promotor_-35 343548..343553 /Source="Nicolas_upshift_promotors" /id="U238" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.993006993006993" /psig="0.993006993006993" /xcortree=1193 /SigmaFactorBS="atatcatcaggcggtttttttctgcaaactgccGGAATGaga acagactggagacGAATAGATATGAAACAAAGaatcattgatgaattaaaacggatcg a" /listShort="ycgL, S115, ycgM, ycgN, S116, ycgO" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 343570..343588 /Source="Nicolas_upshift_promotors" /id="U238" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.993006993006993" /psig="0.993006993006993" /xcortree=1193 /SigmaFactorBS="atatcatcaggcggtttttttctgcaaactgccGGAATGaga acagactggagacGAATAGATATGAAACAAAGaatcattgatgaattaaaacggatcg a" /listShort="ycgL, S115, ycgM, ycgN, S116, ycgO" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 343575 /Source="Nicolas_upshifts" /id="U238" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.993006993006993" /psig="0.993006993006993" /xcortree=1193 /SigmaFactorBS="atatcatcaggcggtttttttctgcaaactgccGGAATGaga acagactggagacGAATAGATATGAAACAAAGaatcattgatgaattaaaacggatcg a" /listShort="ycgL, S115, ycgM, ycgN, S116, ycgO" /GFF_Attribute="listLong" CDS 343578..344360 /gene="ycgL" /locus_tag="BSU_03190" /old_locus_tag="BSU03190" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_388201.1" /db_xref="EnsemblGenomes-Gn:BSU03190" /db_xref="EnsemblGenomes-Tr:CAB12113" /db_xref="InterPro:IPR018775" /db_xref="SubtiList:BG12010" /db_xref="UniProtKB/Swiss-Prot:P94389" /translation="MKQRIIDELKRIEQSYGVKIVYAVESGSRAWGFPSQDSDYDVRF IYVPKKEWYFSIEQERDVIEEPIHDLLDISGWELRKTLRLFKKSNPPLLEWLSSDIVY YEAFTTAEQLRKLRTEAFKPEASVYHYINMARRNVKDYLQGQEVKIKKYFYVLRPILA CQWIEKHGTIPPMDFTVLMNELVAEPELKAEMETLLERKRRGEELDLEARIDVIHQFI ETEIERIMEAAKELKAEKKDMTSELNRLLLNTVEEVWKDGGS*" gene 343578..344360 /gene="ycgL" /locus_tag="BSU_03190" /old_locus_tag="BSU03190" downshifts 344325 /Source="Nicolas_upshifts" /id="D141" /incds=0 /nref=11 /ntot=63 /MaxReadThrough="3.94077" /MaxDrop="4.37398" /score="0.421649027" /energy="-5.9" /TU="U238" /idTUdmin="U236" /TUdmin=2 /isTUend="TRUE" S_feature 344370..344497 /Source="Nicolas_S_feature" /locus_tag="new_344370_344497" /HighExp="S5, S6, S8, S4, S7, B36, B60, BT, S3, S1" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigEF" /TUshortPSig="0.993" /TUlongSig="NA" /TUlongPSig="NA" /label="S115" promotor_-35 344474..344478 /Source="Nicolas_upshift_promotors" /id="U239" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.472527472527473" /psig="0.922077922077922" /xcortree=391 /SigmaFactorBS="cacaaaaataatcagaatctttgtattttgagaatATTGTga acgctggttttgTCCATTTACAATAAACTCATacaaatacttcttagattgcggggtg t" /listShort="ycgM, ycgN, S116, ycgO, S118, ycgP" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 344493..344512 /Source="Nicolas_upshift_promotors" /id="U239" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.472527472527473" /psig="0.922077922077922" /xcortree=391 /SigmaFactorBS="cacaaaaataatcagaatctttgtattttgagaatATTGTga acgctggttttgTCCATTTACAATAAACTCATacaaatacttcttagattgcggggtg t" /listShort="ycgM, ycgN, S116, ycgO, S118, ycgP" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 344499 /Source="Nicolas_upshifts" /id="U239" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.472527472527473" /psig="0.922077922077922" /xcortree=391 /SigmaFactorBS="cacaaaaataatcagaatctttgtattttgagaatATTGTga acgctggttttgTCCATTTACAATAAACTCATacaaatacttcttagattgcggggtg t" /listShort="ycgM, ycgN, S116, ycgO, S118, ycgP" /GFF_Attribute="listLong" CDS 344551..345462 /gene="putB" /locus_tag="BSU_03200" /old_locus_tag="BSU03200" /EC_number="1.5.5.2" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:17536821, 2118500, 21840319, 22139509, 26735940" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 17536821, 2118500, 21840319, 22139509, 26735940; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="proline oxidase" /protein_id="NP_388202.1" /db_xref="EnsemblGenomes-Gn:BSU03200" /db_xref="EnsemblGenomes-Tr:CAB12114" /db_xref="GOA:P94390" /db_xref="InterPro:IPR002872" /db_xref="InterPro:IPR008219" /db_xref="InterPro:IPR015659" /db_xref="InterPro:IPR029041" /db_xref="SubtiList:BG12011" /db_xref="UniProtKB/Swiss-Prot:P94390" /translation="MITRDFFLFLSKSGFLNKMARNWGSRVAAGKIIGGNDFNSSIPT IRQLNSQGLSVTVDHLGEFVNSAEVARERTEECIQTIATIADQELNSHVSLKMTSLGL DIDMDLVYENMTKILQTAEKHKIMVTIDMEDEVRCQKTLDIFKDFRKKYEHVSTVLQA YLYRTEKDIDDLDSLNPFLRLVKGAYKESEKVAFPEKSDVDENYKKIIRKQLLNGHYT AIATHDDKMIDFTKQLAKEHGIANDKFEFQMLYGMRSQTQLSLVKEGYNMRVYLPYGE DWYGYFMRRLAERPSNIAFAFKGMTKK*" gene 344551..345462 /gene="putB" /locus_tag="BSU_03200" /old_locus_tag="BSU03200" CDS 345479..347026 /gene="putC" /locus_tag="BSU_03210" /old_locus_tag="BSU03210" /EC_number="1.2.1.88" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:11418582, 17183215, 21840319, 22139509, 25355936" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11418582, 17183215, 21840319, 22139509, 25355936; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="1-pyrroline-5-carboxylate dehydrogenase" /protein_id="NP_388203.2" /db_xref="EnsemblGenomes-Gn:BSU03210" /db_xref="EnsemblGenomes-Tr:CAB12115" /db_xref="GOA:P94391" /db_xref="InterPro:IPR005932" /db_xref="InterPro:IPR015590" /db_xref="InterPro:IPR016160" /db_xref="InterPro:IPR016161" /db_xref="InterPro:IPR016162" /db_xref="InterPro:IPR029510" /db_xref="SubtiList:BG12012" /db_xref="UniProtKB/Swiss-Prot:P94391" /translation="MTTPYKHEPFTNFQDQNNVEAFKKALATVSEYLGKDYPLVINGE RVETEAKIVSINPADKEEVVGRVSKASQEHAEQAIQAAAKAFEEWRYTSPEERAAVLF RAAAKVRRRKHEFSALLVKEAGKPWNEADADTAEAIDFMEYYARQMIELAKGKPVNSR EGEKNQYVYTPTGVTVVIPPWNFLFAIMAGTTVAPIVTGNTVVLKPASATPVIAAKFV EVLEESGLPKGVVNFVPGSGAEVGDYLVDHPKTSLITFTGSREVGTRIFERAAKVQPG QQHLKRVIAEMGGKDTVVVDEDADIELAAQSIFTSAFGFAGQKCSAGSRAVVHEKVYD QVLERVIEITESKVTAKPDSADVYMGPVIDQGSYDKIMSYIEIGKQEGRLVSGGTGDD SKGYFIKPTIFADLDPKARLMQEEIFGPVVAFCKVSDFDEALEVANNTEYGLTGAVIT NNRKHIERAKQEFHVGNLYFNRNCTGAIVGYHPFGGFKMSGTDSKAGGPDYLALHMQA KTISEMF*" gene 345479..347026 /gene="putC" /locus_tag="BSU_03210" /old_locus_tag="BSU03210" promotor_-35 346450..346456 /Source="Nicolas_upshift_promotors" /id="U240" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.411588411588412" /psig="0.994005994005994" /xcortree=2488 /SigmaFactorBS="ggctttgcgggacaaaaatgctctgcaggttcACGTGCAgta gttcatgaaaAAGTGTATGATCAAGTATTAgagcgtgtcattgaaattacggaatcaa a" /listShort="S116, ycgO, S118, ycgP" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 346470..346489 /Source="Nicolas_upshift_promotors" /id="U240" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.411588411588412" /psig="0.994005994005994" /xcortree=2488 /SigmaFactorBS="ggctttgcgggacaaaaatgctctgcaggttcACGTGCAgta gttcatgaaaAAGTGTATGATCAAGTATTAgagcgtgtcattgaaattacggaatcaa a" /listShort="S116, ycgO, S118, ycgP" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 346478 /Source="Nicolas_upshifts" /id="U240" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.411588411588412" /psig="0.994005994005994" /xcortree=2488 /SigmaFactorBS="ggctttgcgggacaaaaatgctctgcaggttcACGTGCAgta gttcatgaaaAAGTGTATGATCAAGTATTAgagcgtgtcattgaaattacggaatcaa a" /listShort="S116, ycgO, S118, ycgP" /GFF_Attribute="listLong" promotor_-35 346561..346567 /Source="Nicolas_upshift_promotors" /id="U241" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.793206793206793" /psig=1 /xcortree=2403 /SigmaFactorBS="aaacctgacagtgcagatgtttatatgggaccTGTCATTgac caaggttctTATGATAAAATTATGAGCTAtattgagatcggaaaacaggaagggcgtt t" /listShort="S116, ycgO" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 346580..346599 /Source="Nicolas_upshift_promotors" /id="U241" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.793206793206793" /psig=1 /xcortree=2403 /SigmaFactorBS="aaacctgacagtgcagatgtttatatgggaccTGTCATTgac caaggttctTATGATAAAATTATGAGCTAtattgagatcggaaaacaggaagggcgtt t" /listShort="S116, ycgO" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 346589 /Source="Nicolas_upshifts" /id="U241" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.793206793206793" /psig=1 /xcortree=2403 /SigmaFactorBS="aaacctgacagtgcagatgtttatatgggaccTGTCATTgac caaggttctTATGATAAAATTATGAGCTAtattgagatcggaaaacaggaagggcgtt t" /listShort="S116, ycgO" /GFF_Attribute="listLong" misc_feature 347025..347029 /Source="Nicolas_upshift_promotors" /id="U242" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.315684315684316" /psig="0.248751248751249" /xcortree=3009 /SigmaFactorBS="cgggccggattacttggctctgcatatgcaagcaaaaacaat cagtgaaatgttctAAGCGggactaaatgggcatcctccctgcgggggtgtccatttc a" /listShort="S116, ycgO, S118, ycgP" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" S_feature 347027..347149 /Source="Nicolas_S_feature" /locus_tag="new_347027_347149" /HighExp="S1, T2.0H, T2.30H, Lbstat, aero, HiOs, BC, Sw, LPh, T3.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.52312199999999998" /TUshortSig="Sig-, SigA, SigA, SigA, SigEF" /TUshortPSig="0.249, 1, 0.994, 0.922, 0.993" /TUlongSig="NA" /TUlongPSig="NA" /label="S116" upshifts 347029 /Source="Nicolas_upshifts" /id="U242" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.315684315684316" /psig="0.248751248751249" /xcortree=3009 /SigmaFactorBS="cgggccggattacttggctctgcatatgcaagcaaaaacaat cagtgaaatgttctAAGCGggactaaatgggcatcctccctgcgggggtgtccatttc a" /listShort="S116, ycgO, S118, ycgP" /GFF_Attribute="listLong" CDS 347150..348571 /gene="putP" /locus_tag="BSU_03220" /old_locus_tag="BSU03220" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:11902719, 14976255, 15849754, 16850406, 21840319, 22139509, 24142252" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11902719, 14976255, 15849754, 16850406, 21840319, 22139509, 24142252; Product type t: transporter" /codon_start=1 /transl_table=11 /product="proline permease" /protein_id="NP_388204.2" /db_xref="EnsemblGenomes-Gn:BSU03220" /db_xref="EnsemblGenomes-Tr:CAB12116" /db_xref="GOA:P94392" /db_xref="InterPro:IPR001734" /db_xref="InterPro:IPR011851" /db_xref="InterPro:IPR018212" /db_xref="SubtiList:BG12013" /db_xref="UniProtKB/Swiss-Prot:P94392" /translation="MLLIGYFAYKRTSNLTDYMLGGRSLGPAVTALSAGAADMSGWLL MGLPGAMFSTGLSGAWIVIGLCLGAWANWLYVAPRLRTYTEKAGNSITIPGFLENRFG DQTKLLRLFSGIVILVFFTFYVSSGMVSGGVLFNSILGMDYHTGLWIVTGVVVAYTLF GGFLAVSWTDFVQGIIMFAALILVPIVTFFHTGGAGDTVAEIRSVDPDMFNIFKGTSV LGIISLFAWGLGYFGQPHIIVRFMAITSVKEIKRARRIGMGWMILSAVGAVLTGLGGI AYYHQRGMTLKDPETIFIQLGNILFHPIITGFLISAILAAIMSTISSQLLVTSSSLVE DLYKSMFRRSASDKELVFLGRLAVLAVSIVALVLAWEKNNTILGLVSYAWAGFGASFG PVVLLSLFWKRMTKWGALAGMIVGAATVIIWANAGLSDFLYEMIPGFAASLLSVFFVS ILTQAPSQAVTDQFNDYQDTMSQ*" gene 347150..348571 /gene="putP" /locus_tag="BSU_03220" /old_locus_tag="BSU03220" S_feature complement(347670..349525) /Source="Nicolas_S_feature" /locus_tag="new_347670_349525_c" /HighExp="T1.0H, T1.30H, T0.30H, T2.0H, T2.30H, T3.0H, T3.30H, C30, T4.0H, Lbstat" /AntisenseName="ycgP" /AntisenseCor="0.143781082577395" /AntisenseRegPval="-1.7" /CDS_PredictionProba="NA" /TUshortSig="SigD" /TUshortPSig="0.679" /TUlongSig="NA" /TUlongPSig="NA" /label="S117" downshifts 348551 /Source="Nicolas_upshifts" /id="D142" /incds=0 /nref=21 /ntot=160 /MaxReadThrough="5.09597" /MaxDrop="4.17771" /score="5.89792272" /energy="-15.9" /TU="U239,U240,U242" /idTUdmin="U238" /TUdmin=4 /isTUend="TRUE" S_feature 348596..348692 /Source="Nicolas_S_feature" /locus_tag="new_348596_348692" /HighExp="S1, LPh, T2.0H, HPh, aero, Lbstat, LoTm, T2.30H, Cold, HiOs" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="Sig-, SigA, SigA" /TUshortPSig="0.249, 0.994, 0.922" /TUlongSig="NA" /TUlongPSig="NA" /label="S118" promotor_-35 348663..348670 /Source="Nicolas_upshift_promotors" /id="U243" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.985014985014985" /psig=1 /xcortree=2392 /SigmaFactorBS="tttttcttttggaaacaaacgtattttttTCTATACAaaaag accccgtatGGATATGATTAAAGTAAAAAaagtataggagaaaaaggtatggaagagc t" /listShort="ycgP" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 348685..348704 /Source="Nicolas_upshift_promotors" /id="U243" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.985014985014985" /psig=1 /xcortree=2392 /SigmaFactorBS="tttttcttttggaaacaaacgtattttttTCTATACAaaaag accccgtatGGATATGATTAAAGTAAAAAaagtataggagaaaaaggtatggaagagc t" /listShort="ycgP" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 348694 /Source="Nicolas_upshifts" /id="U243" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.985014985014985" /psig=1 /xcortree=2392 /SigmaFactorBS="tttttcttttggaaacaaacgtattttttTCTATACAaaaag accccgtatGGATATGATTAAAGTAAAAAaagtataggagaaaaaggtatggaagagc t" /listShort="ycgP" /GFF_Attribute="listLong" CDS 348724..349959 /gene="putR" /locus_tag="BSU_03230" /old_locus_tag="BSU03230" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:21840319, 21964733, 22139509" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 21840319, 21964733, 22139509; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional activator of proline degradationoperon" /protein_id="NP_388205.2" /db_xref="EnsemblGenomes-Gn:BSU03230" /db_xref="EnsemblGenomes-Tr:CAB12117" /db_xref="GOA:P94393" /db_xref="InterPro:IPR025736" /db_xref="InterPro:IPR029016" /db_xref="SubtiList:BG12014" /db_xref="UniProtKB/Swiss-Prot:P94393" /translation="MEELLERVFSFSDVDKLIDFISYELQKPVILESADFFLLAYNSY YINHFDSANQQTIFSKKCPVQIFERFLKDGIIEKLKTEPEPFRVNKIESIGLNQRVVV SAKHKGEVMGYIWIQELDQNLTDEELDFLYETSFHVGKIIYKTNKLKQEKEEKAEDLI KRAIYQQFTSEKELRREAERINTVLPSMFSVVILHAANGDGEAVEDLKENIRSYLNLR DKVSHVLTIESNIVIVVASFSQKSSVSSAASEFINKLLTHFHFQKIPTPIYIGIGNEY NHLLKLGKSYTEALEVIKAAEITGNQENIPYEYAKLGIYRYLESIEQKNEFLEYENKD LALLKAKDEESSTELLKTLEIYLLNNCKTKPAAEQLFIHQNTLNYRIKQITEMTSIDL SDFRTRCQLYLDLMLMKKK*" gene 348724..349959 /gene="putR" /locus_tag="BSU_03230" /old_locus_tag="BSU03230" promotor_-10 complement(349518..349536) /Source="Nicolas_upshift_promotors" /id="U244" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp="0.679320679320679" /psig="0.679320679320679" /xcortree=1717 /SigmaFactorBS="tcaagtgcttctgtgtagctcttgccaagttttaatagGTGA TTATattcgtttccgatACCGATATAAATAGGGGTAggtattttttgaaagtgaaaat g" /listShort="S117" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(349535) /Source="Nicolas_upshifts" /id="U244" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp="0.679320679320679" /psig="0.679320679320679" /xcortree=1717 /SigmaFactorBS="tcaagtgcttctgtgtagctcttgccaagttttaatagGTGA TTATattcgtttccgatACCGATATAAATAGGGGTAggtattttttgaaagtgaaaat g" /listShort="S117" /GFF_Attribute="listLong" promotor_-35 complement(349550..349557) /Source="Nicolas_upshift_promotors" /id="U244" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp="0.679320679320679" /psig="0.679320679320679" /xcortree=1717 /SigmaFactorBS="tcaagtgcttctgtgtagctcttgccaagttttaatagGTGA TTATattcgtttccgatACCGATATAAATAGGGGTAggtattttttgaaagtgaaaat g" /listShort="S117" /GFF_Attribute="listLong" /label="promotor_-35" downshifts complement(349943) /Source="Nicolas_upshifts" /id="D143" /incds=0 /nref=1 /ntot=5 /MaxReadThrough="0.0291099999999993" /MaxDrop="3.08474" /score="-9.94728494" /energy="-16.9" /TU="NA" /idTUdmin="U245" /TUdmin=66 /isTUend="FALSE" CDS complement(349996..350853) /gene="ycgQ" /locus_tag="BSU_03240" /old_locus_tag="BSU03240" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_388206.1" /db_xref="EnsemblGenomes-Gn:BSU03240" /db_xref="EnsemblGenomes-Tr:CAB12118" /db_xref="GOA:P94394" /db_xref="InterPro:IPR015402" /db_xref="SubtiList:BG12015" /db_xref="UniProtKB/Swiss-Prot:P94394" /translation="MFRLLVLMGFTFFFYHLHASGNLTKYINMKYAYLSFIAIFLLAI LTAVQAYLFIKSPEKSGHHHDHDCGCGHDHEHDHEQNKPFYQRYLIYVVFLFPLVSGI FFPIATLDSSIVKTKGFSFKAMESGDHYSQTQYLRPDASLYYAQDSYDKQMKQLFNKY SSKKEISLTDDDFLKGMETIYNYPGEFLGRTIEFHGFAYKGNAINKNQLFVLRFGIIH CIADSGVYGMLVEFPKDMDIKDDEWIHIKGTLASEYYQPFKSTLPVVKVTDWNTIKKP DDPYVYRGF*" gene complement(349996..350853) /gene="ycgQ" /locus_tag="BSU_03240" /old_locus_tag="BSU03240" downshifts complement(350009) /Source="Nicolas_upshifts" /id="D144" /incds=0 /nref=48 /ntot=167 /MaxReadThrough="1.97725" /MaxDrop="4.53007" /score="-9.94728494" /energy="-16.9" /TU="NA" /idTUdmin="U245" /TUdmin=0 /isTUend="TRUE" CDS complement(350858..351742) /gene="ycgR" /locus_tag="BSU_03250" /old_locus_tag="BSU03250" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative permease" /protein_id="NP_388207.1" /db_xref="EnsemblGenomes-Gn:BSU03250" /db_xref="EnsemblGenomes-Tr:CAB12119" /db_xref="GOA:P94395" /db_xref="InterPro:IPR005524" /db_xref="SubtiList:BG12016" /db_xref="UniProtKB/Swiss-Prot:P94395" /translation="MTAQSSFLQLNSIFISILIEAIPFILIGVILSGIIQMFVSEEMI ARIMPKNRFLAVLFGALAGVLFPACECGIIPITRRLLLKGVPLHAGVAFMLTAPIINP IVLFSTYIAFGNRWSVVFYRGGLALAVSLIIGVILSYQFKDNQLLKPDEPGHHHHHHG TLLQKLGGTLRHAIDEFFSVGKYLIIGAFIAAAMQTYVKTSTLLAIGQNDVSSSLVMM GLAFVLSLCSEVDAFIASSFSSTFSLGSLIAFLVFGAMVDIKNLLMMLAAFKKRFVFL LITYIVVIVLAGSLLVKG*" gene complement(350858..351742) /gene="ycgR" /locus_tag="BSU_03250" /old_locus_tag="BSU03250" upshifts complement(351794) /Source="Nicolas_upshifts" /id="U245" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp="0.566433566433566" /psig="0.566433566433566" /xcortree=2523 /SigmaFactorBS="tttggaatcctaaccaaagTGAAACGATcctttcccctcctc CGTCAAACAAGCAGtgcctttttttctggtatcataagaaaggcagcttaacatgagc g" /listShort="ycgR, ycgQ" /GFF_Attribute="listLong" promotor_-10 complement(351799..351812) /Source="Nicolas_upshift_promotors" /id="U245" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp="0.566433566433566" /psig="0.566433566433566" /xcortree=2523 /SigmaFactorBS="tttggaatcctaaccaaagTGAAACGATcctttcccctcctc CGTCAAACAAGCAGtgcctttttttctggtatcataagaaaggcagcttaacatgagc g" /listShort="ycgR, ycgQ" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 complement(351827..351835) /Source="Nicolas_upshift_promotors" /id="U245" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp="0.566433566433566" /psig="0.566433566433566" /xcortree=2523 /SigmaFactorBS="tttggaatcctaaccaaagTGAAACGATcctttcccctcctc CGTCAAACAAGCAGtgcctttttttctggtatcataagaaaggcagcttaacatgagc g" /listShort="ycgR, ycgQ" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(351842..352696) /gene="ycgS" /locus_tag="BSU_03260" /old_locus_tag="BSU03260" /EC_number="3.7.1.-" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative aromatic hydrocarbon hydrolase" /protein_id="NP_388208.1" /db_xref="EnsemblGenomes-Gn:BSU03260" /db_xref="EnsemblGenomes-Tr:CAB12120" /db_xref="GOA:P94396" /db_xref="InterPro:IPR000073" /db_xref="InterPro:IPR029058" /db_xref="SubtiList:BG12017" /db_xref="UniProtKB/Swiss-Prot:P94396" /translation="MKRRVETITFDGGTLEYSVTGKGTPILVMHGGHSNCYEEFGYTA LIEQGYSIITPSRPGYGRTSKEIGKSLANACRFYVKLLDHLQIESVHVIAISAGGPSG ICFASHYPERVNTLTLQSAVTKEWLTPKDTEYKLGEILFRPPVEKWIWKLISSLNNAF PRLMFRAMSPQFSTLPFQRIKSLMNEKDIEAFRKMNSRQRSGEGFLIDLSQTAAVSLK DLQAIICPVLIMQSVYDGLVDLSHAHHAKEHIRGAVLCLLHSWGHLIWLGKEAAETGS ILLGFLES*" gene complement(351842..352696) /gene="ycgS" /locus_tag="BSU_03260" /old_locus_tag="BSU03260" promotor_-10 complement(352715..352734) /Source="Nicolas_upshift_promotors" /id="U246" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.715284715284715" /psig=1 /xcortree=1859 /SigmaFactorBS="gtatatcatatttcaagggcctttgtttattcatttcttcta cCTTGtggtcaattgctgaAAACTCTATAATAGGCAAAAaccaattgggtgaaacaga t" /listShort="ycgS, ycgR" /listLong="ycgQ" /label="promotor_-10" upshifts complement(352735) /Source="Nicolas_upshifts" /id="U246" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.715284715284715" /psig=1 /xcortree=1859 /SigmaFactorBS="gtatatcatatttcaagggcctttgtttattcatttcttcta cCTTGtggtcaattgctgaAAACTCTATAATAGGCAAAAaccaattgggtgaaacaga t" /listShort="ycgS, ycgR" /listLong="ycgQ" promotor_-35 complement(352749..352752) /Source="Nicolas_upshift_promotors" /id="U246" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.715284715284715" /psig=1 /xcortree=1859 /SigmaFactorBS="gtatatcatatttcaagggcctttgtttattcatttcttcta cCTTGtggtcaattgctgaAAACTCTATAATAGGCAAAAaccaattgggtgaaacaga t" /listShort="ycgS, ycgR" /listLong="ycgQ" /label="promotor_-35" misc_feature 352786..352805 /Source="Nicolas_upshift_promotors" /id="U247" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.762237762237762" /psig="0.993006993006993" /xcortree=2116 /SigmaFactorBS="ttcagcaattgaccacaaggtagaagaaatgaataaacaaag gcccttgaaaTATGATATACTTTGTATTGAtattcattctcaattaaaactttgatat a" /listShort="S119, ycgT, S120" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" promotor_-10 complement(352786..352804) /Source="Nicolas_upshift_promotors" /id="U248" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.966033966033966" /psig="0.966033966033966" /xcortree=774 /SigmaFactorBS="agccatccgtcctgcctcccgttcacatctatatcaaaGTTT TAattgagaatgaatatCAATACAAAGTATATCATAtttcaagggcctttgtttattc a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 352793..352857 /Source="Nicolas_S_feature" /locus_tag="new_352793_352857" /HighExp="B60, Lbexp, LBGexp, dia0, B36, HiOs, GM 15, GM 10, Salt, dia5" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.993" /TUlongSig="NA" /TUlongPSig="NA" /label="S119" upshifts 352794 /Source="Nicolas_upshifts" /id="U247" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.762237762237762" /psig="0.993006993006993" /xcortree=2116 /SigmaFactorBS="ttcagcaattgaccacaaggtagaagaaatgaataaacaaag gcccttgaaaTATGATATACTTTGTATTGAtattcattctcaattaaaactttgatat a" /listShort="S119, ycgT, S120" /GFF_Attribute="listLong" upshifts complement(352803) /Source="Nicolas_upshifts" /id="U248" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.966033966033966" /psig="0.966033966033966" /xcortree=774 /SigmaFactorBS="agccatccgtcctgcctcccgttcacatctatatcaaaGTTT TAattgagaatgaatatCAATACAAAGTATATCATAtttcaagggcctttgtttattc a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(352820..352825) /Source="Nicolas_upshift_promotors" /id="U248" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.966033966033966" /psig="0.966033966033966" /xcortree=774 /SigmaFactorBS="agccatccgtcctgcctcccgttcacatctatatcaaaGTTT TAattgagaatgaatatCAATACAAAGTATATCATAtttcaagggcctttgtttattc a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" CDS 352858..353868 /gene="ffoR" /locus_tag="BSU_03270" /old_locus_tag="BSU03270" /EC_number="1.18.1.-" /EC_number="1.8.1.-" /function="16.6: Maintain" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:16672620, 25826316" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16672620, 25826316; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="Fur-regulated NADPH:ferredoxin oxidoreductase" /protein_id="NP_388209.1" /db_xref="EnsemblGenomes-Gn:BSU03270" /db_xref="EnsemblGenomes-Tr:CAB12121" /db_xref="GOA:O31475" /db_xref="InterPro:IPR000103" /db_xref="InterPro:IPR022890" /db_xref="InterPro:IPR023753" /db_xref="InterPro:IPR036188" /db_xref="SubtiList:BG12018" /db_xref="UniProtKB/Swiss-Prot:O31475" /translation="MAENQEVYDVTIIGGGPIGLFTAFYCGMRELKTKVIEFLPKLGG KVSLFFPEKIIRDIGGIPGIAGKQLIEQLKEQAATFDPDIVLNQRVTGFERLDDGTIV LTGSEGKKHYTRTVILACGMGTLEVNEFDSEDAARYAGKNLHYGVEKLDAFKGKRVVI SGGGDTAVDWANELEPIAASVTVVHRREEFGGMESSVTKMKQSSVRVLTPYRLEQLNG DEEGIKSVTVCHTESGQRKDIEIDELIINHGFKIDLGPMMEWGLEIEEGRVKADRHMR TNLPGVFVAGDAAFYESKLRLIAGGFTEGPTAVNSAKAYLDPKAENMAMYSTHHKKLV HK*" gene 352858..353868 /gene="ffoR" /locus_tag="BSU_03270" /old_locus_tag="BSU03270" S_feature 353869..356316 /Source="Nicolas_S_feature" /locus_tag="new_353869_356316" /HighExp="B60, Lbexp, GM 10, GM 25, HiOs, GM 15, dia0, GM 45, LBGexp, H2O2" /AntisenseName="nasF" /AntisenseCor="-0.30348565853404702" /AntisenseRegPval="-6.4" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.993" /TUlongSig="NA" /TUlongPSig="NA" /label="S120" CDS complement(353900..355351) /gene="nasF" /locus_tag="BSU_03280" /old_locus_tag="BSU03280" /EC_number="2.1.1.107" /function="16.10: Respire" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:9765565, 10217486, 15028686" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9765565, 10217486, 15028686; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="uroporphyrin-III C-methyltransferase" /protein_id="NP_388210.1" /db_xref="EnsemblGenomes-Gn:BSU03280" /db_xref="EnsemblGenomes-Tr:CAB12122" /db_xref="GOA:P42437" /db_xref="InterPro:IPR000878" /db_xref="InterPro:IPR003043" /db_xref="InterPro:IPR006366" /db_xref="InterPro:IPR012409" /db_xref="InterPro:IPR014776" /db_xref="InterPro:IPR014777" /db_xref="InterPro:IPR035996" /db_xref="InterPro:IPR036108" /db_xref="SubtiList:BG11098" /db_xref="UniProtKB/Swiss-Prot:P42437" /translation="MIMKNGIVYFVGAGPGDPGLLTIKGKQALKEADVILYDRLANPK LLEFASPDCQFIYCGKLPNRHFMKQKEINALLVEKALNGLTVVRLKGGDPSVFGRVGE EADALHEHGIRYEMVPGITSGIAAPLYAGIPVTHRDFASSFAMITAHDKSLKGTPNLD WEGLARSVQTLVFYMGVKNLSYICQQLISYGKSPSVPVIVIQWGTWGRQRSVKGTLEN IQQKVQEHQITNPAIIVIGDIVNFQTHSWFESKPLIGRHLMVVTHGEDEDPLADKLRD SGADLIEWPKWRTENMPVNEEILRKIGTFEDVFFTSRRAVCEFFRALASQKIDIRQLT AKLSAASEQAKTELEKRGFLVTAIQPDSEKRLVVGSRHAVENMQKHESCSFYITHENV IDDRFTHMIQRTISESPLHMVICPNKLSVQQLINGGEQIGILPEPSASRPPIVCIGDD SAAGIYGFTAVQEQDELLAFIHNQHAEKKLLHT*" gene complement(353900..355351) /gene="nasF" /locus_tag="BSU_03280" /old_locus_tag="BSU03280" downshifts complement(353904) /Source="Nicolas_upshifts" /id="D145" /incds=0 /nref=131 /ntot=230 /MaxReadThrough="1.40657" /MaxDrop="6.58881" /score="10.9556399" /energy="-11.7" /TU="NA" /idTUdmin="U250" /TUdmin="-1" /isTUend="TRUE" CDS complement(355412..355732) /gene="nasE" /locus_tag="BSU_03290" /old_locus_tag="BSU03290" /EC_number="1.7.1.4" /function="16.2: Construct biomass (Anabolism)" /function="16.10: Respire" /experiment="publication(s) with functional evidences, PMID:10217486, 15028686, 9765565, 22103536" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10217486, 15028686, 9765565, 22103536; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="assimilatory nitrite reductase subunit" /protein_id="NP_388211.1" /db_xref="EnsemblGenomes-Gn:BSU03290" /db_xref="EnsemblGenomes-Tr:CAB12123" /db_xref="GOA:P42436" /db_xref="InterPro:IPR012748" /db_xref="InterPro:IPR017941" /db_xref="InterPro:IPR036922" /db_xref="SubtiList:BG11097" /db_xref="UniProtKB/Swiss-Prot:P42436" /translation="MVNKDVTKVCIGKIEELPEQLGKTVYIEDKELAVFKLSDGSIRA IENRCPHKGGVLAEGIVSGQYVFCPMHDWKISLEDGIVQEPDHGCVKTYETLIEGEHV YLVY*" gene complement(355412..355732) /gene="nasE" /locus_tag="BSU_03290" /old_locus_tag="BSU03290" promotor_-35 355583..355588 /Source="Nicolas_upshift_promotors" /id="U249" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.965034965034965" /psig="0.00899100899100899" /xcortree=84 /SigmaFactorBS="tgacgatgccttctgccaggacgccgcccttatgCGGACAgc ggttttcaatgGCGCGgatgcttccgtctgaaagcttgaaaaccgcgagctccttatc t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 355602..355606 /Source="Nicolas_upshift_promotors" /id="U249" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.965034965034965" /psig="0.00899100899100899" /xcortree=84 /SigmaFactorBS="tgacgatgccttctgccaggacgccgcccttatgCGGACAgc ggttttcaatgGCGCGgatgcttccgtctgaaagcttgaaaaccgcgagctccttatc t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 355609 /Source="Nicolas_upshifts" /id="U249" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.965034965034965" /psig="0.00899100899100899" /xcortree=84 /SigmaFactorBS="tgacgatgccttctgccaggacgccgcccttatgCGGACAgc ggttttcaatgGCGCGgatgcttccgtctgaaagcttgaaaaccgcgagctccttatc t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" upshifts complement(355641) /Source="Nicolas_upshifts" /id="U250" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.853146853146853" /psig="0.957042957042957" /xcortree=1590 /SigmaFactorBS="tcggaaaaattgaagaatTGCCTGAAcaattaggcaaaaCAG TGTATATTGAAGATAAGgagctcgcggttttcaagctttcagacggaagcatccgcgc c" /listShort="nasF" /GFF_Attribute="listLong" promotor_-10 complement(355643..355662) /Source="Nicolas_upshift_promotors" /id="U250" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.853146853146853" /psig="0.957042957042957" /xcortree=1590 /SigmaFactorBS="tcggaaaaattgaagaatTGCCTGAAcaattaggcaaaaCAG TGTATATTGAAGATAAGgagctcgcggttttcaagctttcagacggaagcatccgcgc c" /listShort="nasF" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 complement(355676..355683) /Source="Nicolas_upshift_promotors" /id="U250" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.853146853146853" /psig="0.957042957042957" /xcortree=1590 /SigmaFactorBS="tcggaaaaattgaagaatTGCCTGAAcaattaggcaaaaCAG TGTATATTGAAGATAAGgagctcgcggttttcaagctttcagacggaagcatccgcgc c" /listShort="nasF" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(355764..358181) /gene="nasD" /locus_tag="BSU_03300" /old_locus_tag="BSU03300" /EC_number="1.7.1.4" /function="16.2: Construct biomass (Anabolism)" /function="16.10: Respire" /experiment="publication(s) with functional evidences, PMID:10972836, 15028686, 9765565, 16428414, 22103536" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10972836, 15028686, 9765565, 16428414, 22103536; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="assimilatory nitrite reductase subunit" /protein_id="NP_388212.1" /db_xref="EnsemblGenomes-Gn:BSU03300" /db_xref="EnsemblGenomes-Tr:CAB12124" /db_xref="GOA:P42435" /db_xref="InterPro:IPR005117" /db_xref="InterPro:IPR006066" /db_xref="InterPro:IPR006067" /db_xref="InterPro:IPR007419" /db_xref="InterPro:IPR012744" /db_xref="InterPro:IPR017121" /db_xref="InterPro:IPR023753" /db_xref="InterPro:IPR036136" /db_xref="InterPro:IPR036188" /db_xref="SubtiList:BG11096" /db_xref="UniProtKB/Swiss-Prot:P42435" /translation="MGKKQLVLVGNGMAGVRAIEEILSVAKDEFQITIFGAEPHPNYN RILLSKVLQGDTDIKDITLNDWDWYEENNIQLYTNETVIKVDTENKTVITDADRIQPY DELILATGSVPFILPIPGADKKGVTAFRDIKDTDTMLAASKQYKKAAVIGGGLLGLEA ARGLLNLGMDVSVIHLAPFLMERQLDATAGRLLQNELEKQGMTFLLEKQTEEIVGDDR VEGLRFKDGTSIEADLVVMAVGIRPNTTLGAESGIPVNRGIIVNDYMQTEIPHIYAVG ECAEHRGIAYGLVAPLYEQAKVLAKHMCGIETKPYEGSVLSTQLKVSGVEVFSAGDFN ESEEKKAIKVFDEQDGIYKKIVLRGNQIVGAVLFGDSSEGNRLFSMIQKEADISETSK ISILQPLSQEAGTSITAAMSDDEIICGCNGVSKGAIIQAIQEKGCSSTDEIKACTGAS RSCGGCKPLVEEILQHTLGSDFDASAQKEAICGCTTLSRDEVVEEIKAKGLSHTREVM NVLGWKTPEGCSKCRPALNYYLGMINPTKYEDDRTSRFVNERMHANIQKDGTYSVVPR MYGGVTNSTDLRKIADVVDKYEIPLVKMTGGQRIDLIGVKKEDLPKVWEDLDMPSGYA YGKTLRTVKTCVGEQFCRFGTQDSMALGIALEKKFEGLNTPHKVKMAVSACPRNCAES GIKDLGVVGIDGGWELYVGGNGGTHLRAGDLLMKVKTNEEVLEYAGAYLQYYRETANY LERTSAWLERVGLSHVQSVLNDPEKRQELNGRMNETLSVHKDPWKDFLEDKQTSKELF ENVVTTS*" gene complement(355764..358181) /gene="nasD" /locus_tag="BSU_03300" /old_locus_tag="BSU03300" promotor_-10 complement(358206..358225) /Source="Nicolas_upshift_promotors" /id="U251" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.915084915084915" /psig="0.998001998001998" /xcortree=1620 /SigmaFactorBS="cttttcgtatattttgttacattttataacatgtatcTTAAA TAttcctttttgcTGTGCTACGCTGGAAAAAACatttgataaggagcggatcatctga t" /listShort="nasD, nasE, nasF" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(358220) /Source="Nicolas_upshifts" /id="U251" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.915084915084915" /psig="0.998001998001998" /xcortree=1620 /SigmaFactorBS="cttttcgtatattttgttacattttataacatgtatcTTAAA TAttcctttttgcTGTGCTACGCTGGAAAAAACatttgataaggagcggatcatctga t" /listShort="nasD, nasE, nasF" /GFF_Attribute="listLong" promotor_-35 complement(358237..358243) /Source="Nicolas_upshift_promotors" /id="U251" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.915084915084915" /psig="0.998001998001998" /xcortree=1620 /SigmaFactorBS="cttttcgtatattttgttacattttataacatgtatcTTAAA TAttcctttttgcTGTGCTACGCTGGAAAAAACatttgataaggagcggatcatctga t" /listShort="nasD, nasE, nasF" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(358303..360435) /gene="nasC" /locus_tag="BSU_03310" /old_locus_tag="BSU03310" /EC_number="1.7.99.4" /function="16.2: Construct biomass (Anabolism)" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:10972836, 15028686, 9765565" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10972836, 15028686, 9765565; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="assimilatory nitrate reductase (catalytic subunit)" /protein_id="NP_388213.2" /db_xref="EnsemblGenomes-Gn:BSU03310" /db_xref="EnsemblGenomes-Tr:CAB12125" /db_xref="GOA:P42434" /db_xref="InterPro:IPR006655" /db_xref="InterPro:IPR006656" /db_xref="InterPro:IPR006657" /db_xref="InterPro:IPR006963" /db_xref="InterPro:IPR009010" /db_xref="InterPro:IPR027467" /db_xref="SubtiList:BG11095" /db_xref="UniProtKB/Swiss-Prot:P42434" /translation="MTERLLRYFRDKQQDVQSEKTYDTQCPFCSMQCKMQLVEQTIVT RKKYTAIGIDNPTTQGRLCIKGMNAHQHALNSSRITRPLLKKNGEFMPVSWEEALNHI KDQVTMIQTEHGHDAMAVYGSASITNEEAYLLGKFARVGLQTKYIDYNGRLCMSAAAT AANQTFGADRGLTNPLSDIPHTRVIILAGTNIAECQPTIMPYFEKAKENGAYFIAIDP RETATTKIADLHLKIKPGTDAALANGLVKIIIDEQLINEDFIQSRTNGFEELKQHTDS LDLNDIAEQTSVSLVDIRKAAVKFAKETSGMLFTARGIEQQTDGTAAVKGFLNMVLIT GKIGKPYSGYGAITGQGNGQGAREHGQKADQLPGYRSIENEEHRAHIAKVWGIHQDEL PRKGVSAYEMMEKINDGDIKGLFLMCSNPAVSSPNANLVKKALRRLTFFVAIDLFISE TAKYADVILPASSYLEDEGTMTNVEGRVTLREASRPCPGEAKHDWQIICDLASALGKG RYFSYTSAEDIFNELREASRGGIADYSGISYGRLRREGGIHWPCPESDHPGTGRLFTE SFAHPDQKAALSVIPNEPPVPKEKPTADYPLYLTTGRVMSHYLTGVQTRKSAALAARH FESFMEIHPQTAATYNIEDRVLVKIESPRGSITVRSKLSEQIRKDTVFVPIHWADAQN VNDLIGEALDPACKMPGFKVCAVRIIPI*" gene complement(358303..360435) /gene="nasC" /locus_tag="BSU_03310" /old_locus_tag="BSU03310" CDS complement(360442..362757) /gene="nasB" /locus_tag="BSU_03320" /old_locus_tag="BSU03320" /EC_number="1.7.1.3" /function="16.2: Construct biomass (Anabolism)" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:7836289, 8799114, 9765565, 10940050, 10972836, 15028686, 24122235" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7836289, 8799114, 9765565, 10940050, 10972836, 15028686, 24122235; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="assimilatory nitrate reductase (electron transfer subunit NasB)" /protein_id="NP_388214.2" /db_xref="EnsemblGenomes-Gn:BSU03320" /db_xref="EnsemblGenomes-Tr:CAB12126" /db_xref="GOA:P42433" /db_xref="InterPro:IPR005117" /db_xref="InterPro:IPR007419" /db_xref="InterPro:IPR012744" /db_xref="InterPro:IPR017121" /db_xref="InterPro:IPR023753" /db_xref="InterPro:IPR036136" /db_xref="InterPro:IPR036188" /db_xref="SubtiList:BG11094" /db_xref="UniProtKB/Swiss-Prot:P42433" /translation="MKKQRLVLAGNGMAGIRCIEEVLKLNRHMFEIVIFGSEPHPNYN RILLSSVLQGEASLDDITLNSKDWYDKHGITLYTGETVIQIDTDQQQVITDRKRTLSY DKLIVATGSSPHILPIPGADKKGVYGFRTIEDCQALMNMAQHFQKAAVIGAGLLGLEA AVGLQHLGMDVSVIHHSAGIMQKQLDQTAARLLQTELEQKGLTFLLEKDTVSISGATK ADRIHFKDGSSLKADLIVMAAGVKPNIELAVSAGIKVNRGIIVNDFMQTSEPNIYAVG ECAEHNGTVYGLVAPLYEQGKALASHICGVPCEEYQGSAPSAALKIAGIDVWSAGKIQ EDERTTSIKIYDEQAGVYKKALFVDDKLAGVILFGDTRDKQRLLDSLLKQRDISIAKK QIIEPETSGPLFESMPSSETICQCNTVTKGAIEDAVHTNSLTTVEEVKHCTKATGSCG GCKPLVEDLLRYMTNSEYTKPASTPSFCSCTDFTEDDIIAELQRRPFTNPAEVMNQLD WKTKNGCSTCVPAIQYYLEMLYPGFVQPEPATEETCILIPQMYGGRTNAEQLRTIANI IEAYSIPDVSITHGQRLKLSGIKPADLPNMKKDLKMPVYTNEHRHALQSIKACTCGQN RSIQQLAAQIERQLEMLPLPAPISISLSCETDCTEAALQDVGAIRTQAGWDIHIGGVR GTHARSGALFCVTENEDSTAGMIKGLIQYYRETAHYLEGVHQWIDRLGIVHIREVLFE EDLRAQLLESLQTDLSLIQNPTVETGAYKKG*" gene complement(360442..362757) /gene="nasB" /locus_tag="BSU_03320" /old_locus_tag="BSU03320" promotor_no_box complement(362776..362876) /Source="Nicolas_upshift_promotors" /id="U252" /multdbtbs="SigA" /comp="M21" /sig="Sig-" /pcomp="0.241758241758242" /psig="0.410589410589411" /xcortree=313 /SigmaFactorBS="ttattttctggaaaagacatgtgtaagtttttgtgacacgtt taatgcgttaacaatgcattgtgacataatttttaataggagaaaacttacgagcttc g" /listShort="nasB, nasC, nasD, nasE, nasF" /GFF_Attribute="listLong" /label="promotor_no_box" upshifts complement(362816) /Source="Nicolas_upshifts" /id="U252" /multdbtbs="SigA" /comp="M21" /sig="Sig-" /pcomp="0.241758241758242" /psig="0.410589410589411" /xcortree=313 /SigmaFactorBS="ttattttctggaaaagacatgtgtaagtttttgtgacacgtt taatgcgttaacaatgcattgtgacataatttttaataggagaaaacttacgagcttc g" /listShort="nasB, nasC, nasD, nasE, nasF" /GFF_Attribute="listLong" promotor_-35 362859..362866 /Source="Nicolas_upshift_promotors" /id="U253" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.613386613386613" /psig="0.928071928071928" /xcortree=319 /SigmaFactorBS="ttaaacgtgtcacaaaaacttacacatGTCTTTTCcagaaaa taatggTCCTATATCCTTGATTCAGAaaatgtaaaataatgagggtctagaaagggga a" /listShort="nasA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 362880..362899 /Source="Nicolas_upshift_promotors" /id="U253" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.613386613386613" /psig="0.928071928071928" /xcortree=319 /SigmaFactorBS="ttaaacgtgtcacaaaaacttacacatGTCTTTTCcagaaaa taatggTCCTATATCCTTGATTCAGAaaatgtaaaataatgagggtctagaaagggga a" /listShort="nasA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 362892 /Source="Nicolas_upshifts" /id="U253" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.613386613386613" /psig="0.928071928071928" /xcortree=319 /SigmaFactorBS="ttaaacgtgtcacaaaaacttacacatGTCTTTTCcagaaaa taatggTCCTATATCCTTGATTCAGAaaatgtaaaataatgagggtctagaaagggga a" /listShort="nasA" /GFF_Attribute="listLong" CDS 362937..364142 /gene="nasA" /locus_tag="BSU_03330" /old_locus_tag="BSU03330" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 7868621, 12823818, 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative nitrate transporter" /protein_id="NP_388215.2" /db_xref="EnsemblGenomes-Gn:BSU03330" /db_xref="EnsemblGenomes-Tr:CAB12127" /db_xref="GOA:P42432" /db_xref="InterPro:IPR004737" /db_xref="InterPro:IPR011701" /db_xref="InterPro:IPR020846" /db_xref="InterPro:IPR036259" /db_xref="SubtiList:BG11093" /db_xref="UniProtKB/Swiss-Prot:P42432" /translation="MKLSELKTSGHPLTLLCSFLYFDVSFMIWVMLGALGVYISQDFG LSPFEKGLVVAVPILSGSVFRIILGILTDRIGPKKTAVIGMLVTMIPLLWGTFGGRSL TELYAIGILLGVAGASFAVALPMASRWYPPHLQGLAMGIAGAGNSGTLFATLFGPRLA EQFGWHIVMGIALIPLLIVFILFVSMAKDSPAQPSPQPLKSYLHVFGQKETWFFCLLY SVTFGGFVGLSSFLSIFFVDQYQLSKIHAGDFVTLCVAAGSFFRPVGGLISDRVGGTK VLSVLFVIVALCMAGVSSLPSLSMVIVLLFVGMMGLGMGNGAVFQLVPQRFRKEIGMV TGIVGAAGGIGGFFLPNILGSLKQMTGTYAIGFITFSCIALLAFALVLAAGYYWRKSW SAESSPADV*" gene 362937..364142 /gene="nasA" /locus_tag="BSU_03330" /old_locus_tag="BSU03330" downshifts 364127 /Source="Nicolas_upshifts" /id="D146" /incds=0 /nref=1 /ntot=3 /MaxReadThrough="2.02479" /MaxDrop="3.6823" /score="39.2612286" /energy="-11.9" /TU="NA" /idTUdmin="U253" /TUdmin=0 /isTUend="TRUE" promotor_-35 364186..364192 /Source="Nicolas_upshift_promotors" /id="U254" /multdbtbs="SigA" /comp="M17" /sig="SigA" /pcomp="0.362637362637363" /psig="0.998001998001998" /xcortree=667 /SigmaFactorBS="cacgcgtttgtgcgtgtcttttttattttctCTTGATTttca acagtgaaccGATCAAAATAAATAGTAATTattacgatttgttagtgagaggagtttt c" /listShort="folEB, yciB" /listLong="yczL, yciC" /label="promotor_-35" promotor_-10 364207..364226 /Source="Nicolas_upshift_promotors" /id="U254" /multdbtbs="SigA" /comp="M17" /sig="SigA" /pcomp="0.362637362637363" /psig="0.998001998001998" /xcortree=667 /SigmaFactorBS="cacgcgtttgtgcgtgtcttttttattttctCTTGATTttca acagtgaaccGATCAAAATAAATAGTAATTattacgatttgttagtgagaggagtttt c" /listShort="folEB, yciB" /listLong="yczL, yciC" /label="promotor_-10" upshifts 364215 /Source="Nicolas_upshifts" /id="U254" /multdbtbs="SigA" /comp="M17" /sig="SigA" /pcomp="0.362637362637363" /psig="0.998001998001998" /xcortree=667 /SigmaFactorBS="cacgcgtttgtgcgtgtcttttttattttctCTTGATTttca acagtgaaccGATCAAAATAAATAGTAATTattacgatttgttagtgagaggagtttt c" /listShort="folEB, yciB" /listLong="yczL, yciC" CDS 364259..365173 /gene="folEB" /locus_tag="BSU_03340" /old_locus_tag="BSU03340" /EC_number="3.5.4.16" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:12426338, 17032654, 19767425" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12426338, 17032654, 19767425; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="GTP cyclohydrolase I" /protein_id="NP_388216.2" /db_xref="EnsemblGenomes-Gn:BSU03340" /db_xref="EnsemblGenomes-Tr:CAB12128" /db_xref="GOA:P94398" /db_xref="InterPro:IPR003801" /db_xref="InterPro:IPR022838" /db_xref="SubtiList:BG12019" /db_xref="UniProtKB/Swiss-Prot:P94398" /translation="MNQHTLLPKKTERLQYFGSVSPIKGEKPVEKEKMKDLQNIRKDY FFDIQHVGVANVSHPVTITSAMMPAEQTTAANFTMTCNLPRNQKGINMSRLTELLQVY HQNGWILSFSSLQQFTKELAENMDTSSATVEVRFPWFFERKSPKLEKAGLMHADIFMS VTYRKDQPFKQRAGISAKVTTLCPCSKEISEYSAHNQRGTVSIWADIHPAASLPSDVK ADLLHAAESNASARLHPVLKRPDEKAVTETAYENPRFVEDLARLIAADLFELEWVSAF EIECRNEESIHLHDAYAKLCFSKEVDKI*" gene 364259..365173 /gene="folEB" /locus_tag="BSU_03340" /old_locus_tag="BSU03340" CDS 365170..365754 /gene="yciB" /locus_tag="BSU_03350" /old_locus_tag="BSU03350" /function="16.1: Circulate" /function="16.13: Shape" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 12426338, 20013255; Product type f: factor" /codon_start=1 /transl_table=11 /product="putative Zn(2+)-dependent division lipoprotein (schizosome)" /protein_id="NP_388217.2" /db_xref="EnsemblGenomes-Gn:BSU03350" /db_xref="EnsemblGenomes-Tr:CAB12129" /db_xref="GOA:C0SP99" /db_xref="InterPro:IPR005490" /db_xref="SubtiList:BG12020" /db_xref="UniProtKB/Swiss-Prot:C0SP99" /translation="MKLSLFIIAVLMPVILLSACSDHAEEHASINTKKTVENITDVRK TAKTSIDWTKPSGGEYPDIKQKHVWIDVNVKEQKAYIKEGSNTIYTMMISSGLDQTKD DATPKGTFYVEPERGEWFFSEGYQEGAEYWVSWKNHGEFLFHSVPMTKDQKVIKTEAE KLGTKASHGCIRLTIPDAKWVYENIPEHTKVVIS*" gene 365170..365754 /gene="yciB" /locus_tag="BSU_03350" /old_locus_tag="BSU03350" promotor_-35 365765..365772 /Source="Nicolas_upshift_promotors" /id="U255" /multdbtbs="SigA" /comp="M17" /sig="SigA" /pcomp="0.671328671328671" /psig=1 /xcortree=668 /SigmaFactorBS="aaaagtggtgatcagctgaattgaaaaccGTTGACAAaaagg aaaaaagaCCATACAATTTAAATCGTAAcaattacgttttatgataaatggcttatca t" /listShort="yczL, yciC, S121" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 365786..365805 /Source="Nicolas_upshift_promotors" /id="U255" /multdbtbs="SigA" /comp="M17" /sig="SigA" /pcomp="0.671328671328671" /psig=1 /xcortree=668 /SigmaFactorBS="aaaagtggtgatcagctgaattgaaaaccGTTGACAAaaagg aaaaaagaCCATACAATTTAAATCGTAAcaattacgttttatgataaatggcttatca t" /listShort="yczL, yciC, S121" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 365796 /Source="Nicolas_upshifts" /id="U255" /multdbtbs="SigA" /comp="M17" /sig="SigA" /pcomp="0.671328671328671" /psig=1 /xcortree=668 /SigmaFactorBS="aaaagtggtgatcagctgaattgaaaaccGTTGACAAaaagg aaaaaagaCCATACAATTTAAATCGTAAcaattacgttttatgataaatggcttatca t" /listShort="yczL, yciC, S121" /GFF_Attribute="listLong" CDS 365850..366035 /gene="yczL" /locus_tag="BSU_03359" /old_locus_tag="BSU03359" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_003097674.1" /db_xref="EnsemblGenomes-Gn:BSU03359" /db_xref="EnsemblGenomes-Tr:CAX52544" /db_xref="UniProtKB/Swiss-Prot:C0H3U7" /translation="MKSGKASIKDLAVGKGKDLRWGKGLNAVGVFTDLEIGRQREMSA KSCSTPLYIRRSIQFKS*" gene 365850..366035 /gene="yczL" /locus_tag="BSU_03359" /old_locus_tag="BSU03359" CDS 366063..367256 /gene="zinU" /locus_tag="BSU_03360" /old_locus_tag="BSU03360" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:2013568, 9811636, 12426338, 18344368, 19648245, 27060116, 27561249" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 2013568, 9811636, 12426338, 18344368, 19648245, 27060116, 27561249; Product type t: transporter" /codon_start=1 /transl_table=11 /product="zinc metallochaperone with NTPase activity" /protein_id="NP_388218.1" /db_xref="EnsemblGenomes-Gn:BSU03360" /db_xref="EnsemblGenomes-Tr:CAB12130" /db_xref="GOA:P94400" /db_xref="InterPro:IPR003495" /db_xref="InterPro:IPR011629" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR036627" /db_xref="SubtiList:BG12021" /db_xref="UniProtKB/Swiss-Prot:P94400" /translation="MKKIPVTVLSGYLGAGKTTLLNSILQNREGLKIAVIVNDMSEVN IDAGLVKQEGGLSRTDEKLVEMSNGCICCTLREDLLIEVEKLAKDGRFDYIVIESTGI SEPIPVAQTFSYIDEEMGIDLTKFCQLDTMVTVVDANRFWHDYQSGESLLDRKEALGE KDEREIADLLIDQIEFCDVLILNKCDLVSEQELEQLENVLRKLQPRARFIRSVKGNVK PQEILHTGLFNFEEASGSAGWIQELTAGHAEHTPETEEYGISSFVYKRRLPFHSTRFY RWLDQMPKNVVRAKGIVWCASHNNLALLMSQAGPSVTIEPVSYWVAALPKLEQEQVKQ QEPEILEEWDPEFGDRLTQLVFIGTDLDEETITKELDQCLLTEYEFDSDWSLFEDPFK WKLNQ*" gene 366063..367256 /gene="zinU" /locus_tag="BSU_03360" /old_locus_tag="BSU03360" downshifts 367248 /Source="Nicolas_upshifts" /id="D147" /incds=0 /nref=26 /ntot=45 /MaxReadThrough="5.12378" /MaxDrop="5.8275" /score="15.6427627" /energy="-9.2" /TU="U255" /idTUdmin="U255" /TUdmin="-792" /isTUend="FALSE" S_feature 367293..368962 /Source="Nicolas_S_feature" /locus_tag="new_367293_368962" /HighExp="Etha, B60, Cold, Heat, B36, C30, BMM, S6, C90, S2" /AntisenseName="yckB" /AntisenseCor="-0.170121935628575" /AntisenseRegPval="-2.2999999999999998" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S121" CDS complement(367305..367985) /gene="yckA" /locus_tag="BSU_03370" /old_locus_tag="BSU03370" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2b: Function from indirect experimental evidences (e.g. phenotypes); PubMedId: 15849754, 16850406, 23038252; Product type t: transporter" /codon_start=1 /transl_table=11 /product="aminoacid ABC transporter (permease subunit)" /protein_id="NP_388219.1" /db_xref="EnsemblGenomes-Gn:BSU03370" /db_xref="EnsemblGenomes-Tr:CAB12131" /db_xref="GOA:P42399" /db_xref="InterPro:IPR000515" /db_xref="InterPro:IPR010065" /db_xref="InterPro:IPR035906" /db_xref="SubtiList:BG11177" /db_xref="UniProtKB/Swiss-Prot:P42399" /translation="MINSIQWEYIFNTKLAIESFPYVIKGIGYTLLISFVSMFAGTVI GLFISLARMSKLALLRWPAKLYISFMRGVPILVILFILYFGFPYIGIEFSAVTAALIG FSLNSAAYIAEINRSAISSVEKGQWEAASSLGLSYWQTMRGIILPQSIRIALPPLANV LLDLIKASSLAAMITVPELLQHAKIIGGREFDYMTMYILTALIYWAICSIAAVFQNIL EKKYAHYV*" gene complement(367305..367985) /gene="yckA" /locus_tag="BSU_03370" /old_locus_tag="BSU03370" downshifts complement(367311) /Source="Nicolas_upshifts" /id="D148" /incds=0 /nref=101 /ntot=231 /MaxReadThrough="0.41655" /MaxDrop="6.18136" /score="40.1548023" /energy="-12.6" /TU="NA" /idTUdmin="U256" /TUdmin="-9" /isTUend="TRUE" CDS complement(367995..368858) /gene="yckB" /locus_tag="BSU_03380" /old_locus_tag="BSU03380" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:23038252" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 23038252; Product type t: transporter" /codon_start=1 /transl_table=11 /product="amino acid ABC transporter (binding lipoprotein subunit)" /protein_id="NP_388220.1" /db_xref="EnsemblGenomes-Gn:BSU03380" /db_xref="EnsemblGenomes-Tr:CAB12132" /db_xref="GOA:P42400" /db_xref="InterPro:IPR001638" /db_xref="InterPro:IPR018313" /db_xref="PDB:2IEE" /db_xref="SubtiList:BG11178" /db_xref="UniProtKB/Swiss-Prot:P42400" /translation="MKSFMHSKAVIFSFTMAFFLILAACSGKNEADSKDTGWEQIKDK GKIVVATSGTLYPTSYHDTDSGSDKLTGYEVEVVREAAKRLGLKVEFKEMGIDGMLTA VNSGQVDAAANDIDVTKDREEKFAFSTPYKYSYGTAIVRKDDLSGIKTLKDLKGKKAA GAATTVYMEVARKYGAKEVIYDNATNEQYLKDVANGRTDVILNDYYLQTLALAAFPDL NITIHPDIKYMPNKQALVMKKSNAALQKKMNEALKEMSKDGSLTKLSKQFFNKADVSK KIDADVQDVDL*" gene complement(367995..368858) /gene="yckB" /locus_tag="BSU_03380" /old_locus_tag="BSU03380" promotor_-10 complement(368880..368899) /Source="Nicolas_upshift_promotors" /id="U256" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.791208791208791" /psig="0.983016983016983" /xcortree=1804 /SigmaFactorBS="caattcgaactttttgaaaacgcgatcaacaTATTGCAAccc cttatgttcaaTGCTATCTTTTTAGTTGATTaacagattgggggaactataggtgaaa t" /listShort="yckB, yckA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(368892) /Source="Nicolas_upshifts" /id="U256" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.791208791208791" /psig="0.983016983016983" /xcortree=1804 /SigmaFactorBS="caattcgaactttttgaaaacgcgatcaacaTATTGCAAccc cttatgttcaaTGCTATCTTTTTAGTTGATTaacagattgggggaactataggtgaaa t" /listShort="yckB, yckA" /GFF_Attribute="listLong" S_feature complement(368894..371728) /Source="Nicolas_S_feature" /locus_tag="new_368894_371728_c" /HighExp="GM 150, T-4.40H, G/S, Pyr, S2, C30, T-5.40H, C90, T-3.40H, T0.30H" /AntisenseName="bglC" /AntisenseCor="-0.37749573319969598" /AntisenseRegPval="-9.8000000000000007" /CDS_PredictionProba="NA" /TUshortSig="Sig-, SigA, Sig-" /TUshortPSig="0.248, 0.994, 0.0879" /TUlongSig="SigD" /TUlongPSig=1 /label="S122" promotor_-35 complement(368914..368921) /Source="Nicolas_upshift_promotors" /id="U256" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.791208791208791" /psig="0.983016983016983" /xcortree=1804 /SigmaFactorBS="caattcgaactttttgaaaacgcgatcaacaTATTGCAAccc cttatgttcaaTGCTATCTTTTTAGTTGATTaacagattgggggaactataggtgaaa t" /listShort="yckB, yckA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 368931..368937 /Source="Nicolas_upshift_promotors" /id="U257" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.996003996003996" /psig="0.996003996003996" /xcortree=154 /SigmaFactorBS="acataaggggttgcaatatgttgatcgCGTTTTCaaaaagtt cgaattGTGTATACAAAAAGCATGGgtgggtgtttaaaagcgtctatgaagggaagag g" /listShort="S123, yckC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 368952..368970 /Source="Nicolas_upshift_promotors" /id="U257" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.996003996003996" /psig="0.996003996003996" /xcortree=154 /SigmaFactorBS="acataaggggttgcaatatgttgatcgCGTTTTCaaaaagtt cgaattGTGTATACAAAAAGCATGGgtgggtgtttaaaagcgtctatgaagggaagag g" /listShort="S123, yckC" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 368964..369186 /Source="Nicolas_S_feature" /locus_tag="new_368964_369186" /HighExp="Etha, Salt, B60, Sw, B36, Gly, Heat, S6, Cold, S7" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.99896700000000005" /TUshortSig="SigB" /TUshortPSig="0.996" /TUlongSig="NA" /TUlongPSig="NA" /label="S123" upshifts 368964 /Source="Nicolas_upshifts" /id="U257" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.996003996003996" /psig="0.996003996003996" /xcortree=154 /SigmaFactorBS="acataaggggttgcaatatgttgatcgCGTTTTCaaaaagtt cgaattGTGTATACAAAAAGCATGGgtgggtgtttaaaagcgtctatgaagggaagag g" /listShort="S123, yckC" /GFF_Attribute="listLong" CDS 369020..369217 /locus_tag="BSU_03385" /old_locus_tag="BSU03385" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_009513942.1" /translation="MSKDECQTYQGNACESEGCSRPVTHLCQYRKKWSRGMKPIFRIN LSLADAPKAYDIFDEKENGNI*" gene 369020..369217 /locus_tag="BSU_03385" /old_locus_tag="BSU03385" promotor_-35 369155..369160 /Source="Nicolas_upshift_promotors" /id="U258" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.876123876123876" /psig="0.876123876123876" /xcortree=779 /SigmaFactorBS="atgaaaccgatcttcagaataaatttaAGTCTTgctgatgcc cctaagGCATATGATATATTCGATGagaaagaaaatggaaacatttaaaccataatgg g" /listShort="yckC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 369176..369194 /Source="Nicolas_upshift_promotors" /id="U258" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.876123876123876" /psig="0.876123876123876" /xcortree=779 /SigmaFactorBS="atgaaaccgatcttcagaataaatttaAGTCTTgctgatgcc cctaagGCATATGATATATTCGATGagaaagaaaatggaaacatttaaaccataatgg g" /listShort="yckC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 369188 /Source="Nicolas_upshifts" /id="U258" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.876123876123876" /psig="0.876123876123876" /xcortree=779 /SigmaFactorBS="atgaaaccgatcttcagaataaatttaAGTCTTgctgatgcc cctaagGCATATGATATATTCGATGagaaagaaaatggaaacatttaaaccataatgg g" /listShort="yckC" /GFF_Attribute="listLong" CDS 369236..369691 /gene="yckC" /locus_tag="BSU_03390" /old_locus_tag="BSU03390" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 15849754, 16850406; Product type m:membrane component" /codon_start=1 /transl_table=11 /product="conserved integral membrane protein of unknown function" /protein_id="NP_388221.1" /db_xref="EnsemblGenomes-Gn:BSU03390" /db_xref="EnsemblGenomes-Tr:CAB12133" /db_xref="GOA:P42401" /db_xref="InterPro:IPR010432" /db_xref="SubtiList:BG11179" /db_xref="UniProtKB/Swiss-Prot:P42401" /translation="MNIYKPAGFWIRLGAALLDYIIVSVPLLLIYWLITGKDPNDSMF ISLVVLLYSILLPMFWRGYLIGKRICGIRIVKKDGSQVSLLTMFLRVIVAGLVYCITF GLGLIASLILIAVREDKRTLHDLIAGTYVTYATPGEEELNADEEIRKSE*" gene 369236..369691 /gene="yckC" /locus_tag="BSU_03390" /old_locus_tag="BSU03390" downshifts 369666 /Source="Nicolas_upshifts" /id="D149" /incds=0 /nref=40 /ntot=193 /MaxReadThrough="1.14817" /MaxDrop="5.48303" /score="23.1539807" /energy="-9.8" /TU="NA" /idTUdmin="U257" /TUdmin="-2" /isTUend="TRUE" promotor_-35 369714..369720 /Source="Nicolas_upshift_promotors" /id="U259" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=899 /SigmaFactorBS="cgaagagattagaaagagcgaataatggttcgctctttttat ttttaTGCATAAaaaatacaaggcaGCAAAACATATGaaaaataggattggaggaata a" /listShort="yckD" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 369727 /Source="Nicolas_upshifts" /id="U259" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=899 /SigmaFactorBS="cgaagagattagaaagagcgaataatggttcgctctttttat ttttaTGCATAAaaaatacaaggcaGCAAAACATATGaaaaataggattggaggaata a" /listShort="yckD" /GFF_Attribute="listLong" promotor_-10 369734..369745 /Source="Nicolas_upshift_promotors" /id="U259" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=899 /SigmaFactorBS="cgaagagattagaaagagcgaataatggttcgctctttttat ttttaTGCATAAaaaatacaaggcaGCAAAACATATGaaaaataggattggaggaata a" /listShort="yckD" /GFF_Attribute="listLong" /label="promotor_-10" CDS 369773..370105 /gene="yckD" /locus_tag="BSU_03400" /old_locus_tag="BSU03400" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type f: factor" /codon_start=1 /transl_table=11 /product="putative exported protein" /protein_id="NP_388222.1" /db_xref="EnsemblGenomes-Gn:BSU03400" /db_xref="EnsemblGenomes-Tr:CAB12134" /db_xref="InterPro:IPR024485" /db_xref="SubtiList:BG11180" /db_xref="UniProtKB/Swiss-Prot:P42402" /translation="MKRITINIITMFIAAAVISLTGTAEAAEKQQQSPANVTLTDQQK KEIEQLEAEILKKRKDVISKYVQYGILPKERGEHIKNHLDKHFEMMKQNGFVPKHHPH PHKFEKRH*" gene 369773..370105 /gene="yckD" /locus_tag="BSU_03400" /old_locus_tag="BSU03400" downshifts 370086 /Source="Nicolas_upshifts" /id="D150" /incds=0 /nref=20 /ntot=44 /MaxReadThrough="2.48743" /MaxDrop="4.3022" /score="-1.40416926" /energy="-11.8" /TU="NA" /idTUdmin="U259" /TUdmin=0 /isTUend="TRUE" promotor_-35 370191..370198 /Source="Nicolas_upshift_promotors" /id="U260" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.936063936063936" /psig="0.953046953046953" /xcortree=1581 /SigmaFactorBS="caatattagctgagctgttccgcgactaacatcGAGTTGATa tgaaacgcgtttcaTAGCCTATGATAGGTTTATCaaataattcaggagtgataaacac t" /listShort="bglC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 370214..370233 /Source="Nicolas_upshift_promotors" /id="U260" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.936063936063936" /psig="0.953046953046953" /xcortree=1581 /SigmaFactorBS="caatattagctgagctgttccgcgactaacatcGAGTTGATa tgaaacgcgtttcaTAGCCTATGATAGGTTTATCaaataattcaggagtgataaacac t" /listShort="bglC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 370218 /Source="Nicolas_upshifts" /id="U260" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.936063936063936" /psig="0.953046953046953" /xcortree=1581 /SigmaFactorBS="caatattagctgagctgttccgcgactaacatcGAGTTGATa tgaaacgcgtttcaTAGCCTATGATAGGTTTATCaaataattcaggagtgataaacac t" /listShort="bglC" /GFF_Attribute="listLong" CDS 370259..371692 /gene="bglC" /locus_tag="BSU_03410" /old_locus_tag="BSU03410" /EC_number="3.2.1.86" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:14652714, 15139916, 18069788" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 14652714, 15139916, 18069788; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="aryl-phospho-beta-d-glucosidase" /protein_id="NP_388223.1" /db_xref="EnsemblGenomes-Gn:BSU03410" /db_xref="EnsemblGenomes-Tr:CAB12135" /db_xref="GOA:P42403" /db_xref="InterPro:IPR001360" /db_xref="InterPro:IPR017853" /db_xref="InterPro:IPR018120" /db_xref="InterPro:IPR033132" /db_xref="SubtiList:BG11181" /db_xref="UniProtKB/Swiss-Prot:P42403" /translation="MIHQHPESFPKHFLWGSASAAYQIEGAWNEDGKGPSVWDVFTKI PGKTFKGTNGEIAVDHYHRFKEDVALMAEMGLKAYRFSVSWPRVFPKGKGEINEAGLA FYDSLIDELLSHHIEPVLTLYHWDLPQALMDEYGGFESRNIIEDFNHYCITLYKRFGD RVKYWVTLNEQNYNFNHGFITAMHPPGVKDRKRFYEANHIAFLANAKAIESFREYVPE GKIGPSFAYSPAYPLSSHPEDILAFENAEEFTNNWWLDMYCWGTYPQIPFRCLEKQGW APTIEAGDMDLLAKGKPDFVGVNYYQTITYERNPLDGVSEGKMNTTGQKGTNQETGIP GVFKTKKNPHLTTSNWDWTIDPIGLRIGLRRITSRYQLPVFITENGLGEFDKVEDGTV QDDYRIDYLRSHLEQCRQAISDGVDLIGYCSWSFTDLLSWLNGYQKRYGFVYVNRDEE STSDLKRLKKKSFYWYQDVIKTNGESL*" gene 370259..371692 /gene="bglC" /locus_tag="BSU_03410" /old_locus_tag="BSU03410" downshifts 371670 /Source="Nicolas_upshifts" /id="D151" /incds=0 /nref=12 /ntot=61 /MaxReadThrough="1.51167" /MaxDrop="4.6748" /score="18.0928088" /energy="-15.9" /TU="NA" /idTUdmin="U260" /TUdmin=0 /isTUend="TRUE" CDS complement(371729..372127) /gene="nin" /locus_tag="BSU_03420" /old_locus_tag="BSU03420" /function="16.3: Control" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:11359569, 11814663, 22720735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11359569, 11814663, 22720735; Product type r: regulator" /codon_start=1 /transl_table=11 /product="inhibitor of the DNA degrading activity of NucA (competence)" /protein_id="NP_388224.1" /db_xref="EnsemblGenomes-Gn:BSU03420" /db_xref="EnsemblGenomes-Tr:CAB12136" /db_xref="GOA:P12669" /db_xref="InterPro:IPR020354" /db_xref="PDB:4MQD" /db_xref="SubtiList:BG10839" /db_xref="UniProtKB/Swiss-Prot:P12669" /translation="MIKSWKPQELSISYHQFTVFQKDSTPPVMDWTDEAIEKGYAAAD GAISFEAQRNTKAFILFRLNSSETVNSYEKKVTVPFHVTENGIHIESIMSKRLSFDLP KGDYQLTCWTVPAEMSDLHADTYIIDAVSV*" gene complement(371729..372127) /gene="nin" /locus_tag="BSU_03420" /old_locus_tag="BSU03420" promotor_no_box complement(372124..372224) /Source="Nicolas_upshift_promotors" /id="U261" /multdbtbs="-" /comp="M18" /sig="Sig-" /pcomp="0.234765234765235" /psig="0.247752247752248" /xcortree=1715 /SigmaFactorBS="caggctcttgggtcgggcatcggcttaccgattacccagacg gcacaaaggttttattcacaattcagtaaacagtacatagaggaggaacagcacattg a" /listShort="nin, S122" /GFF_Attribute="listLong" /label="promotor_no_box" CDS complement(372154..372603) /gene="nucA" /locus_tag="BSU_03430" /old_locus_tag="BSU03430" /function="16.11: Scavenge (Catabolism)" /function="16.8: Protect" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:2841296, 7746143, 11359569, 11814663" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 2841296, 7746143, 11359569, 11814663; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="endonuclease" /protein_id="NP_388225.3" /db_xref="EnsemblGenomes-Gn:BSU03430" /db_xref="EnsemblGenomes-Tr:CAB12137" /db_xref="GOA:P12667" /db_xref="InterPro:IPR029476" /db_xref="SubtiList:BG10838" /db_xref="UniProtKB/Swiss-Prot:P12667" /translation="MNITTDIIKTILLVIVIIAAAAVGLIKGDFFSADQKTSQTKEYD ETMAFPSDRYPETAKHIKDAINEGHSEVCTIDRDGAEERREQSLKDVPSKKGYDRDEW PMAMCKEGGEGASVEYISPADNRGAGSWVGHRLTDYPDGTKVLFTIQ*" gene complement(372154..372603) /gene="nucA" /locus_tag="BSU_03430" /old_locus_tag="BSU03430" upshifts complement(372164) /Source="Nicolas_upshifts" /id="U261" /multdbtbs="-" /comp="M18" /sig="Sig-" /pcomp="0.234765234765235" /psig="0.247752247752248" /xcortree=1715 /SigmaFactorBS="caggctcttgggtcgggcatcggcttaccgattacccagacg gcacaaaggttttattcacaattcagtaaacagtacatagaggaggaacagcacattg a" /listShort="nin, S122" /GFF_Attribute="listLong" promotor_-10 complement(372618..372637) /Source="Nicolas_upshift_promotors" /id="U262" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.532467532467532" /psig="0.994005994005994" /xcortree=2957 /SigmaFactorBS="taaactgatcgtaaaacataaaatttaaACCTTTACaccaaa tgctttcTGGATTACTCTTGTGTCAGTtttaaaagcgggaggtgaacatcacgacgga c" /listShort="nucA, nin, S122, yckB, yckA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(372626) /Source="Nicolas_upshifts" /id="U262" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.532467532467532" /psig="0.994005994005994" /xcortree=2957 /SigmaFactorBS="taaactgatcgtaaaacataaaatttaaACCTTTACaccaaa tgctttcTGGATTACTCTTGTGTCAGTtttaaaagcgggaggtgaacatcacgacgga c" /listShort="nucA, nin, S122, yckB, yckA" /GFF_Attribute="listLong" S_feature complement(372628..372770) /Source="Nicolas_S_feature" /locus_tag="new_372628_372770_c" /HighExp="C30, Diami, M40t45, Cold, Lbstat, T0.30H, M0t90, dia15, C90, Lbtran" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="Sig-, SigD" /TUshortPSig="0.0879, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S124" promotor_-35 complement(372651..372658) /Source="Nicolas_upshift_promotors" /id="U262" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.532467532467532" /psig="0.994005994005994" /xcortree=2957 /SigmaFactorBS="taaactgatcgtaaaacataaaatttaaACCTTTACaccaaa tgctttcTGGATTACTCTTGTGTCAGTtttaaaagcgggaggtgaacatcacgacgga c" /listShort="nucA, nin, S122, yckB, yckA" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(372771..374492) /gene="tlpC" /locus_tag="BSU_03440" /old_locus_tag="BSU03440" /function="16.12: Sense" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:7704255, 7921238, 15187186, 27899502" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7704255, 7921238, 15187186, 27899502; Product type rc: receptor" /codon_start=1 /transl_table=11 /product="methyl-accepting chemotaxis protein (plant colonization)" /protein_id="NP_388226.2" /db_xref="EnsemblGenomes-Gn:BSU03440" /db_xref="EnsemblGenomes-Tr:CAB12138" /db_xref="GOA:P39209" /db_xref="InterPro:IPR003660" /db_xref="InterPro:IPR004089" /db_xref="InterPro:IPR004090" /db_xref="InterPro:IPR029151" /db_xref="InterPro:IPR033463" /db_xref="SubtiList:BG10790" /db_xref="UniProtKB/Swiss-Prot:P39209" /translation="MLIKRFKMKLGTKILCLVFVVILLFSASVGTVMLKEITESMKQM ATEKAKGDLALSSTYIDDVMSGDWQVKNNKLYKGQTQINGNEDIVDLLGEKTGDTITI FQGDTRVATNVMKNGERAVGTQASSEVIAAVLKKGKRFYGQADVAGSSYQTAYMPLKD QNGNIIGMLYTGANQSILASLTQSLFTQFAIVLVIVIMVSVILVLVFTRKINKRLNAL KSAFESAGNGDMTIEVSDKTGDELSELSVYYNKMRMKLNDTIQTVQQSALQLASASQQ LSAGAEETNQASEKITEAVQQIANGAQDQITRIENSESSLKQASADIRDISANTAAIA DKGQLAQSKADIGQKEIANVQAQMDAIHQSIQKSGEIIHQLDGRSKQIEQILSVITQI ADQTNLLALNAAIEAARAGEQGKGFAVVADEVRKLAEESQQSAGQISKLIIEIQKDMN RSARSVEHVKTEAAEGVTMIQRTRDAFKEIAAATGEISAEISDLSASVTNISASAHQI NDSFAANTADIKESTKNTRQAAALTEEQFAAMEEITAASETLSQLAEELTGIISQFKM INQAENG*" gene complement(372771..374492) /gene="tlpC" /locus_tag="BSU_03440" /old_locus_tag="BSU03440" promotor_-35 372783..372790 /Source="Nicolas_upshift_promotors" /id="U263" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.955044955044955" /psig="0.996003996003996" /xcortree=2959 /SigmaFactorBS="ttgccaatttacaataatgatagtaagtcatcagccgttttc GGCTTGATtaatcattttaaatTGGCTTATGATACCGGTAAGctcctcagctaattga g" /listShort="S125, hxlR" /GFF_Attribute="listLong" /label="promotor_-35" S_feature 372801..375944 /Source="Nicolas_S_feature" /locus_tag="new_372801_375944" /HighExp="T1.0H, T1.30H, T0.30H, T2.0H, T2.30H, T3.0H, T3.30H, T4.0H, T0.0H, T-0.40H" /AntisenseName="tlpC" /AntisenseCor="-0.40398083053643302" /AntisenseRegPval="-11.3" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.996" /TUlongSig="NA" /TUlongPSig="NA" /label="S125" upshifts 372801 /Source="Nicolas_upshifts" /id="U263" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.955044955044955" /psig="0.996003996003996" /xcortree=2959 /SigmaFactorBS="ttgccaatttacaataatgatagtaagtcatcagccgttttc GGCTTGATtaatcattttaaatTGGCTTATGATACCGGTAAGctcctcagctaattga g" /listShort="S125, hxlR" /GFF_Attribute="listLong" promotor_-10 372805..372824 /Source="Nicolas_upshift_promotors" /id="U263" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.955044955044955" /psig="0.996003996003996" /xcortree=2959 /SigmaFactorBS="ttgccaatttacaataatgatagtaagtcatcagccgttttc GGCTTGATtaatcattttaaatTGGCTTATGATACCGGTAAGctcctcagctaattga g" /listShort="S125, hxlR" /GFF_Attribute="listLong" /label="promotor_-10" promotor_no_box complement(372806..372906) /Source="Nicolas_upshift_promotors" /id="U264" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.452547452547453" /psig="0.0879120879120879" /xcortree=2190 /SigmaFactorBS="ggctgcattaacagaggagcaatttgctgcaatggaggagat taccgcagcttctgaaacactttctcaattagctgaggagcttaccggtatcataagc c" /listShort="S124, nucA, nin, S122" /listLong="yckB, yckA" /label="promotor_no_box" upshifts complement(372846) /Source="Nicolas_upshifts" /id="U264" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.452547452547453" /psig="0.0879120879120879" /xcortree=2190 /SigmaFactorBS="ggctgcattaacagaggagcaatttgctgcaatggaggagat taccgcagcttctgaaacactttctcaattagctgaggagcttaccggtatcataagc c" /listShort="S124, nucA, nin, S122" /listLong="yckB, yckA" promotor_-10 complement(374516..374534) /Source="Nicolas_upshift_promotors" /id="U265" /multdbtbs="SigD" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2796 /SigmaFactorBS="cggcctgaagatcaggccggttttattttttctaaaATAAAA CTttaaacccaaaaaCCCGATAAGTAATATGACCtgcaaatcgtaaagggaggaatta t" /listShort="tlpC, S124, nucA, nin" /listLong="S122" /label="promotor_-10" upshifts complement(374531) /Source="Nicolas_upshifts" /id="U265" /multdbtbs="SigD" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2796 /SigmaFactorBS="cggcctgaagatcaggccggttttattttttctaaaATAAAA CTttaaacccaaaaaCCCGATAAGTAATATGACCtgcaaatcgtaaagggaggaatta t" /listShort="tlpC, S124, nucA, nin" /listLong="S122" promotor_-35 complement(374548..374555) /Source="Nicolas_upshift_promotors" /id="U265" /multdbtbs="SigD" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2796 /SigmaFactorBS="cggcctgaagatcaggccggttttattttttctaaaATAAAA CTttaaacccaaaaaCCCGATAAGTAATATGACCtgcaaatcgtaaagggaggaatta t" /listShort="tlpC, S124, nucA, nin" /listLong="S122" /label="promotor_-35" CDS complement(374603..375160) /gene="hxlB" /locus_tag="BSU_03450" /old_locus_tag="BSU03450" /EC_number="5.3.1.27" /function="16.8: Protect" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:10572115, 15978081" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10572115, 15978081; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="6-phospho-3-hexuloisomerase (PHI)" /protein_id="NP_388227.1" /db_xref="EnsemblGenomes-Gn:BSU03450" /db_xref="EnsemblGenomes-Tr:CAB12139" /db_xref="GOA:P42404" /db_xref="InterPro:IPR001347" /db_xref="InterPro:IPR017552" /db_xref="PDB:1M3S" /db_xref="PDB:1VIV" /db_xref="SubtiList:BG11182" /db_xref="UniProtKB/Swiss-Prot:P42404" /translation="MKTTEYVAEILNELHNSAAYISNEEADQLADHILSSHQIFTAGA GRSGLMAKSFAMRLMHMGFNAHIVGEILTPPLAEGDLVIIGSGSGETKSLIHTAAKAK SLHGIVAALTINPESSIGKQADLIIRMPGSPKDQSNGSYKTIQPMGSLFEQTLLLFYD AVILKLMEKKGLDSETMFTHHANLE*" gene complement(374603..375160) /gene="hxlB" /locus_tag="BSU_03450" /old_locus_tag="BSU03450" downshifts complement(374606) /Source="Nicolas_upshifts" /id="D152" /incds=0 /nref=51 /ntot=130 /MaxReadThrough="1.98332" /MaxDrop="6.56052" /score="42.3682356" /energy="-15.4" /TU="NA" /idTUdmin="U266" /TUdmin=0 /isTUend="TRUE" CDS complement(375166..375798) /gene="hxlA" /locus_tag="BSU_03460" /old_locus_tag="BSU03460" /EC_number="4.1.2.43" /function="16.8: Protect" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:10572115, 15978081" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10572115, 15978081; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="3-hexulose-6-phosphate synthase (HPS)" /protein_id="NP_388228.1" /db_xref="EnsemblGenomes-Gn:BSU03460" /db_xref="EnsemblGenomes-Tr:CAB12140" /db_xref="GOA:P42405" /db_xref="InterPro:IPR001754" /db_xref="InterPro:IPR011060" /db_xref="InterPro:IPR013785" /db_xref="InterPro:IPR017553" /db_xref="SubtiList:BG11183" /db_xref="UniProtKB/Swiss-Prot:P42405" /translation="MELQLALDLVNIPEAIELVKEVEQYIDVVEIGTPVVINEGLRAV KEIKEAFPQLKVLADLKIMDAGGYEIMKASEAGADIITVLGATDDATIKGAVEEAKKQ KKKILVDMINVKDIESRAKEIDALGVDYICVHTGYDLQAEGKNSFEELTTIKNTVKNA KTAIAGGIKLDTLPEVIQQKPDLVIVGGGITSAADKAETASKMKQLIVQG*" gene complement(375166..375798) /gene="hxlA" /locus_tag="BSU_03460" /old_locus_tag="BSU03460" promotor_-10 complement(375824..375843) /Source="Nicolas_upshift_promotors" /id="U266" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.658341658341658" /psig="0.987012987012987" /xcortree=1517 /SigmaFactorBS="agtatcctccaagtaacttgttgacttcaaagtgcctaCTTC tcaacaaaagaaggAACCTATAGAATGAACAATAattcgaaaaagggagtggatcaac a" /listShort="hxlA, hxlB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(375839) /Source="Nicolas_upshifts" /id="U266" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.658341658341658" /psig="0.987012987012987" /xcortree=1517 /SigmaFactorBS="agtatcctccaagtaacttgttgacttcaaagtgcctaCTTC tcaacaaaagaaggAACCTATAGAATGAACAATAattcgaaaaagggagtggatcaac a" /listShort="hxlA, hxlB" /GFF_Attribute="listLong" promotor_-35 complement(375858..375861) /Source="Nicolas_upshift_promotors" /id="U266" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.658341658341658" /psig="0.987012987012987" /xcortree=1517 /SigmaFactorBS="agtatcctccaagtaacttgttgacttcaaagtgcctaCTTC tcaacaaaagaaggAACCTATAGAATGAACAATAattcgaaaaagggagtggatcaac a" /listShort="hxlA, hxlB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 375922..375925 /Source="Nicolas_upshift_promotors" /id="U267" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.536463536463537" /psig=1 /xcortree=1957 /SigmaFactorBS="acttggaggatactgtgaggagagacaatcagatttCTTTcg cttgattttatgAGTGAGTATAATGAAAAAAGagtctgcaaaaaagtaagtaagtgat g" /listShort="hxlR" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 375940..375959 /Source="Nicolas_upshift_promotors" /id="U267" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.536463536463537" /psig=1 /xcortree=1957 /SigmaFactorBS="acttggaggatactgtgaggagagacaatcagatttCTTTcg cttgattttatgAGTGAGTATAATGAAAAAAGagtctgcaaaaaagtaagtaagtgat g" /listShort="hxlR" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 375946 /Source="Nicolas_upshifts" /id="U267" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.536463536463537" /psig=1 /xcortree=1957 /SigmaFactorBS="acttggaggatactgtgaggagagacaatcagatttCTTTcg cttgattttatgAGTGAGTATAATGAAAAAAGagtctgcaaaaaagtaagtaagtgat g" /listShort="hxlR" /GFF_Attribute="listLong" CDS 376032..376394 /gene="hxlR" /locus_tag="BSU_03470" /old_locus_tag="BSU03470" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:15978081, 26973631" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15978081, 26973631; Product type r: regulator" /codon_start=1 /transl_table=11 /product="positive regulator of hxlAB expression (formaldehyde sensing)" /protein_id="NP_388229.2" /db_xref="EnsemblGenomes-Gn:BSU03470" /db_xref="EnsemblGenomes-Tr:CAB12141" /db_xref="GOA:P42406" /db_xref="InterPro:IPR002577" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG11184" /db_xref="UniProtKB/Swiss-Prot:P42406" /translation="MSRMDDKRFNCEKELTLAVIGGKWKMLILWHLGKEGTKRFNELK TLIPDITQKILVNQLRELEQDMIVHREVYPVVPPKVEYSLTPHGESLMPILEAMYEWG KGYMELIDIDKNVMKESL*" gene 376032..376394 /gene="hxlR" /locus_tag="BSU_03470" /old_locus_tag="BSU03470" downshifts 376378 /Source="Nicolas_upshifts" /id="D153" /incds=0 /nref=14 /ntot=154 /MaxReadThrough="3.13609" /MaxDrop="3.66949" /score="20.4643411" /energy="-9.6" /TU="U267" /idTUdmin="U263" /TUdmin="-2" /isTUend="TRUE" promotor_-35 376641..376644 /Source="Nicolas_upshift_promotors" /id="U268" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.658341658341658" /psig="0.994005994005994" /xcortree=3241 /SigmaFactorBS="cggcatcccgcatgaaacttttcacccatttttcGGTGataa aaacatttttTTCATTTAAACTGAACGGTAgaaagataaaaaatattgaaaacaatga a" /listShort="S126, srfAA, srfAB, comS, srfAC, srfAD, ycxA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 376659..376678 /Source="Nicolas_upshift_promotors" /id="U268" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.658341658341658" /psig="0.994005994005994" /xcortree=3241 /SigmaFactorBS="cggcatcccgcatgaaacttttcacccatttttcGGTGataa aaacatttttTTCATTTAAACTGAACGGTAgaaagataaaaaatattgaaaacaatga a" /listShort="S126, srfAA, srfAB, comS, srfAC, srfAD, ycxA" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 376667..376967 /Source="Nicolas_S_feature" /locus_tag="new_376667_376967" /HighExp="HiOs, T-1.10H, T5.0H, T4.0H, T-1.40H, S2, M9-stat, T3.30H, T0.0H, T2.30H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.20585600000000001" /TUshortSig="SigA" /TUshortPSig="0.994" /TUlongSig="NA" /TUlongPSig="NA" /label="S126" upshifts 376667 /Source="Nicolas_upshifts" /id="U268" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.658341658341658" /psig="0.994005994005994" /xcortree=3241 /SigmaFactorBS="cggcatcccgcatgaaacttttcacccatttttcGGTGataa aaacatttttTTCATTTAAACTGAACGGTAgaaagataaaaaatattgaaaacaatga a" /listShort="S126, srfAA, srfAB, comS, srfAC, srfAD, ycxA" /GFF_Attribute="listLong" CDS 376968..387731 /gene="srfAA" /locus_tag="BSU_03480" /old_locus_tag="BSU03480" /function="16.5: Explore" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:15066026, 16166527, 8288534, 8441623, 14762003, 16707694, 26284661, 26268540, 14762003" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15066026, 16166527, 8288534, 8441623, 14762003, 16707694, 26284661, 26268540, 14762003; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="surfactin synthetase" /protein_id="NP_388230.2" /db_xref="EnsemblGenomes-Gn:BSU03480" /db_xref="EnsemblGenomes-Tr:CAB12142" /db_xref="GOA:P27206" /db_xref="InterPro:IPR000873" /db_xref="InterPro:IPR001242" /db_xref="InterPro:IPR006162" /db_xref="InterPro:IPR009081" /db_xref="InterPro:IPR010060" /db_xref="InterPro:IPR010071" /db_xref="InterPro:IPR013321" /db_xref="InterPro:IPR020806" /db_xref="InterPro:IPR020845" /db_xref="InterPro:IPR025110" /db_xref="InterPro:IPR036736" /db_xref="SubtiList:BG10168" /db_xref="UniProtKB/Swiss-Prot:P27206" /translation="MEITFYPLTDAQKRIWYTEKFYPHTSISNLAGIGKLVSADAIDY VLVEQAIQEFIRRNDAMRLRLRLDENGEPVQYISEYRPVDIKHTDTTEDPNAIEFISQ WSREETKKPLPLYDCDLFRFSLFTIKENEVWFYANVHHVISDGISMNILGNAIMHIYL ELASGSETKEGISHSFIDHVLSEQEYAQSKRFEKDKAFWNKQFESVPELVSLKRNASA GGSLDAERFSKDVPEALHQQILSFCEANKVSVLSVFQSLLAAYLYRVSGQNDVVTGTF MGNRTNAKEKQMLGMFVSTVPLRTNIDGGQAFSEFVKDRMKDLMKTLRHQKYPYNLLI NDLRETKSSLTKLFTVSLEYQVMQWQKEEDLAFLTEPIFSGSGLNDVSIHVKDRWDTG KLTIDFDYRTDLFSREEINMICERMITMLENALTHPEHTIDELTLISDAEKEKLLARA GGKSVSYRKDMTIPELFQEKAELLSDHPAVVFEDRTLSYRTLHEQSARIANVLKQKGV GPDSPVAVLIERSERMITAIMGILKAGGAYVPIDPGFPAERIQYILEDCGADFILTES KVAAPEADAELIDLDQAIEEGAEESLNADVNARNLAYIIYTSGTTGRPKGVMIEHRQV HHLVESLQQTIYQSGSQTLRMALLAPFHFDASVKQIFASLLLGQTLYIVPKKTVTNGA ALTAYYRKNSIEATDGTPAHLQMLAAAGDFEGLKLKHMLIGGEGLSSVVADKLLKLFK EAGTAPRLTNVYGPTETCVDASVHPVIPENAVQSAYVPIGKALGNNRLYILDQKGRLQ PEGVAGELYIAGDGVGRGYLHLPELTEEKFLQDPFVPGDRMYRTGDVVRWLPDGTIEY LGREDDQVKVRGYRIELGEIEAVIQQAPDVAKAVVLARPDEQGNLEVCAYVVQKPGSE FAPAGLREHAARQLPDYMVPAYFTEVTEIPLTPSGKVDRRKLFALEVKAVSGTAYTAP RNETEKAIAAIWQDVLNVEKAGIFDNFFETGGHSLKAMTLLTKIHKETGIEIPLQFLF EHPTITALAEEADHRESKAFAVIEPAEKQEHYPLSLAQQRTYIVSQFEDAGVGYNMPA AAILEGPLDIQKLERAFQGLIRRHESLRTSFVLENSTPRQKIHDSVDFNIEMIERGGR SDEAIMASFVRTFDLAKAPLFRIGLLGLEENRHMLLFDMHHLISDGVSIGIMLEELAR IYKGEQLPDLRLQYKDYAVWQSRQAAEGYKKDQAYWKEVFAGELPVLQLLSDYPRPPV QSFEGDRVSIKLDAGVKDRLNRLAEQNGATLYMVMLSAYYTLLSKYTGQDDIIVGTPS AGRNHSDTEGIIGMFVNTLAIRSEVKQNETFTQLISRVRKRVLDAFSHQDYPFEWLVE DLNIPRDVSRHPLFDTMFSLQNATEGIPAVGDLSLSVQETNFKIAKFDLTVQARETDE GIEIDVDYSTKLFKQSTADRLLTHFARLLEDAAADPEKPISEYKLLSEEEAASQIQQF NPGRTPYPKDKTIVQLFEEQAANTPDHTALQYEGESLTYRELNERANRLARGILSLGA GEGRTAAVLCERSMDMIVSILAVLKSGSAYVPIDPEHPIQRMQHFFRDSGAKVLLTQR KLKALAEEAEFKGVIVLADEEESYHADARNLALPLDSAAMANLTYTSGTTGTPKGNIV THANILRTVKETNYLSITEQDTILGLSNYVFDAFMFDMFGSLLNGAKLVLIPKETVLD MARLSRVIERENISILMITTALFHLLVDLNPACLSTLRKIMFGGERASVEHVRKALQT VGKGKLLHMYGPSESTVFATYHPVDELEEHTLSVPIGKPVSNTEVYILDRTGHVQPAG IAGELCVSGEGLVKGYYNRPELTEEKFVPHPFTSGERMYKTGDLARWLPNGDIEFIGR IDHQVKIRGQRIELGEIEHQLQTHDRVQESVVLAVDQGAGDKLLCAYYVGEGDISSQE MREHAAKDLPAYMVPAVFIQMDELPLTGNGKIDRRALPIPDANVSRGVSYVAPRNGTE QKVADIWAQVLQAEQVGAYDHFFDIGGHSLAGMKMLALVHQELGVELSLKDLFQSPTV EGLAQVIASAEKGTAASISPAEKQDTYPVSSPQKRMYVLQQLEDAQTSYNMPAVLRLT GELDVERLNSVMQQLMQRHEALRTTFEIKDGETVQRIWEEAECEIAYFEAPEEETERI VSEFIKPFKIDQLPLFRIGLIKHSDTEHVLLFDMHHIISDGASVGVLIEELSKLYDGE TLEPLRIQYKDYAVWQQQFIQSELYKKQEEHWLKELDGELPVLTLPTDYSRPAVQTFE GDRIAFSLEAGKADALRRLAKETDSTLYMVLLASYSAFLSKISGQDDIIVGSPVAGRS QADVSRVIGMFVNTLALRTYPKGEKTFADYLNEVKETALSAFDAQDYPLEDLIGNVQV QRDTSRNPLFDAVFSMQNANIKDLTMKGIQLEPHPFERKTAKFDLTLTADETDGGLTF VLEYNTALFKQETIERWKQYWMELLDAVTGNPNQPLSSLSLVTETEKQALLEAWKGKA LPVPTDKTVHQLFEETAQRHKDRPAVTYNGQSWTYGELNAKANRLARILMDCGISPDD RVGVLTKPSLEMSAAVLGVLKAGAAFVPIDPDYPDQRIEYILQDSGAKLLLKQEGISV PDSYTGDVILLDGSRTILSLPLDENDEENPETAVTAENLAYMIYTSGTTGQPKGVMVE HHALVNLCFWHHDAFSMTAEDRSAKYAGFGFDASIWEMFPTWTIGAELHVIEEAIRLD IVRLNDYFETNGVTITFLPTQLAEQFMELENTSLRVLLTGGDKLKRAVKKPYTLVNNY GPTENTVVATSAEIHPEEGSLSIGRAIANTRVYILGEGNQVQPEGVAGELCVAGRGLA RGYLNREDETAKRFVADPFVPGERMYRTGDLVKWTGGGIEYIGRIDQQVKVRGYRIEL SEIEVQLAQLSEVQDAAVTAVKDKGGNTAIAAYVTPESADIEALKSALKETLPDYMIP AFWVTLNELPVTANGKVDRKALPEPDIEAGSGEYKAPTTDMEELLAGIWQDVLGMSEV GVTDNFFSLGGDSIKGIQMASRLNQHGWKLEMKDLFQHPTIEELTQYVERAEGKQADQ GPVEGEVILTPIQRWFFEKNFTNKHHWNQSVMLHAKKGFDPERVEKTLQALIEHHDAL RMVYREGQEDVIQYNRGLEAASAQLEVIQIEGQAADYEDRIEREAERLQSSIDLQEGG LLKAGLFQAEDGDHLLLAIHHLVVDGVSWRILLEDFAAVYTQLEQGNEPVLPQKTHSF AEYAERLQDFANSKAFLKEKEYWRQLEEQAVAAKLPKDRESGDQRMKHTKTIEFSLTA EETEQLTTKVHEAYHTEMNDILLTAFGLAMKEWTGQDRVSVHLEGHGREEIIEDLTIS RTVGWFTSMYPMVLDMKHADDLGYQLKQMKEDIRHVPNKGVGYGILRYLTAPEHKEDV AFSIQPDVSFNYLGQFDEMSDAGLFTRSELPSGQSLSPETEKPNALDVVGYIENGKLT MSLAYHSLEFHEKTVQTFSDSFKAHLLRIIEHCLSQDGTELTPSDLGDDDLTLDELDK LMEIF*" gene 376968..387731 /gene="srfAA" /locus_tag="BSU_03480" /old_locus_tag="BSU03480" CDS 387744..398495 /gene="srfAB" /locus_tag="BSU_03490" /old_locus_tag="BSU03490" /function="16.5: Explore" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:15066026, 16166527, 16553878, 17227471, 14762003, 26284661" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15066026, 16166527, 16553878, 17227471, 14762003, 26284661; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="surfactin synthetase" /protein_id="NP_388231.2" /db_xref="EnsemblGenomes-Gn:BSU03490" /db_xref="EnsemblGenomes-Tr:CAB12143" /db_xref="GOA:Q04747" /db_xref="InterPro:IPR000873" /db_xref="InterPro:IPR001242" /db_xref="InterPro:IPR006162" /db_xref="InterPro:IPR009081" /db_xref="InterPro:IPR010060" /db_xref="InterPro:IPR010071" /db_xref="InterPro:IPR020806" /db_xref="InterPro:IPR020845" /db_xref="InterPro:IPR025110" /db_xref="InterPro:IPR036736" /db_xref="SubtiList:BG10169" /db_xref="UniProtKB/Swiss-Prot:Q04747" /translation="MSKKSIQKVYALTPMQEGMLYHAMLDPHSSSYFTQLELGIHGAF DLEIFEKSVNELIRSYDILRTVFVHQQLQKPRQVVLAERKTKVHYEDISHADENRQKE HIERYKQDVQRQGFNLAKDILFKVAVFRLAADQLYLVWSNHHIMMDGWSMGVLMKSLF QNYEALRAGRTPANGQGKPYSDYIKWLGKQDNEEAESYWSERLAGFEQPSVLPGRLPV KKDEYVNKEYSFTWDETLVARIQQTANLHQVTGPNLFQAVWGIVLSKYNFTDDVIFGT VVSGRPSEINGIETMAGLFINTIPVRVKVERDAAFADIFTAVQQHAVEAERYDYVPLY EIQKRSALDGNLLNHLVAFENYPLDQELENGSMEDRLGFSIKVESAFEQTSFDFNLIV YPGKTWTVKIKYNGAAFDSAFIERTAEHLTRMMEAAVDQPAAFVREYGLVGDEEQRQI VEVFNSTKAELPEGMAVHQVFEEQAKRTPASTAVVYEGTKLTYRELNAAANRLARKLV EHGLQKGETAAIMNDRSVETVVGMLAVLKAGAAYVPLDPALPGDRLRFMAEDSSVRMV LIGNSYTGQAHQLQVPVLTLDIGFEESEAADNLNLPSAPSDLAYIMYTSGSTGKPKGV MIEHKSILRLVKNAGYVPVTEEDRMAQTGAVSFDAGTFEVFGALLNGAALYPVKKETL LDAKQFAAFLREQSITTMWLTSPLFNQLAAKDAGMFGTLRHLIIGGDALVPHIVSKVK QASPSLSLWNGYGPTENTTFSTSFLIDREYGGSIPIGKPIGNSTAYIMDEQQCLQPIG APGELCVGGIGVARGYVNLPELTEKQFLEDPFRPGERIYRTGDLARWLPDGNIEFLGR IDNQVKVRGFRIELGEIETKLNMAEHVTEAAVIIRKNKADENEICAYFTADREVAVSE LRKTLSQSLPDYMVPAHLIQMDSLPLTPNGKINKKELPAPQSEAVQPEYAAPKTESEK KLAEIWEGILGVKAGVTDNFFMIGGHSLKAMMMTAKIQEHFHKEVPIKVLFEKPTIQE LALYLEENESKEEQTFEPIRQASYQQHYPVSPAQRRMYILNQLGQANTSYNVPAVLLL EGEVDKDRLENAIQQLINRHEILRTSFDMIDGEVVQTVHKNISFQLEAAKGREEDAEE IIKAFVQPFELNRAPLVRSKLVQLEEKRHLLLIDMHHIITDGSSTGILIGDLAKIYQG ADLELPQIHYKDYAVWHKEQTNYQKDEEYWLDVFKGELPILDLPADFERPAERSFAGE RVMFGLDKQITAQIKSLMAETDTTMYMFLLAAFNVLLSKYASQDDIIVGSPTAGRTHP DLQGVPGMFVNTVALRTAPAGDKTFAQFLEEVKTASLQAFEHQSYPLEELIEKLPLTR DTSRSPLFSVMFNMQNMEIPSLRLGDLKISSYSMLHHVAKFDLSLEAVEREEDIGLSF DYATALFKDETIRRWSRHFVNIIKAAAANPNVRLSDVDLLSSAETAALLEERHMTQIT EATFAALFEKQAQQTPDHSAVKAGGNLLTYRELDEQANQLAHHLRAQGAGNEDIVAIV MDRSAEVMVSILGVMKAGAAFLPIDPDTPEERIRYSLEDSGAKFAVVNERNMTAIGQY EGIIVSLDDGKWRNESKERPSSISGSRNLAYVIYTSGTTGKPKGVQIEHRNLTNYVSW FSEEAGLTENDKTVLLSSYAFDLGYTSMFPVLLGGGELHIVQKETYTAPDEIAHYIKE HGITYIKLTPSLFHTIVNTASFAKDANFESLRLIVLGGEKIIPTDVIAFRKMYGHTEF INHYGPTEATIGAIAGRVDLYEPDAFAKRPTIGRPIANAGALVLNEALKLVPPGASGQ LYITGQGLARGYLNRPQLTAERFVENPYSPGSLMYKTGDVVRRLSDGTLAFIGRADDQ VKIRGYRIEPKEIETVMLSLSGIQEAVVLAVSEGGLQELCAYYTSDQDIEKAELRYQL SLTLPSHMIPAFFVQVDAIPLTANGKTDRNALPKPNAAQSGGKALAAPETALEESLCR IWQKTLGIEAIGIDDNFFDLGGHSLKGMMLIANIQAELEKSVPLKALFEQPTVRQLAA YMEASAVSGGHQVLKPADKQDMYPLSSAQKRMYVLNQLDRQTISYNMPSVLLMEGELD ISRLRDSLNQLVNRHESLRTSFMEANGEPVQRIIEKAEVDLHVFEAKEDEADQKIKEF IRPFDLNDAPLIRAALLRIEAKKHLLLLDMHHIIADGVSRGIFVKELALLYKGEQLPE PTLHYKDFAVWQNEAEQKERMKEHEAYWMSVLSGELPELDLPLDYARPPVQSFKGDTI RFRTGSETAKAVEKLLAETGTTLHMVLHAVFHVFLSKISGQRDIVIGSVTAGRTNADV QDMPGMFVNTLALRMEAKEQQTFAELLELAKQTNLSALEHQEYPFEDLVNQLDLPRDM SRNPLFNVMVTTENPDKEQLTLQNLSISPYEAHQGTSKFDLTLGGFTDENGIGLQLEY ATDLFAKETAEKWSEYVLRLLKAVADNPNQPLSSLLLVTETEKQALLEAWKGKALPVP TDKTVHQLFEETVQRHKDRPAVTYNGQSWTYGELNAKANRLARILMDCGISPDDRVGV LTKPSLEMSAAVLGVLKAGAAFVPIDPDYPDQRIEYILQDSGAKLLLKQEGISVPDSY TGDVILLDGSRTILSLPLDENDEGNPETAVTAENLAYMIYTSGTTGQPKGVMVEHHAL VNLCFWHHDAFSMTAEDRSAKYAGFGFDASIWEMFPTWTIGAELHVIDEAIRLDIVRL NDYFETNGVTITFLPTQLAEQFMELENTSLRVLLTGGDKLKRAVKKPYTLVNNYGPTE NTVVATSAEIHPEEGSLSIGRAIANTRVYILGEGNQVQPEGVAGELCVAGRGLARGYL NREDETAKRFVADPFVPGERMYRTGDLVKWVNGGIEYIGRIDQQVKVRGYRIELSEIE VQLAQLSEVQDAAVTAVKDKGGNTAIAAYVTPETADIEALKSTLKETLPDYMIPAFWV TLNELPVTANGKVDRKALPEPDIEAGSGEYKAPTTDMEELLAGIWQDVLGMSEVGVTD NFFSLGGDSIKGIQMASRLNQHGWKLEMKDLFQHPTIEELTQYVERAEGKQADQGPVE GEVILTPIQRWFFEKNFTNKHHWNQSVMLHAKKGFDPERVEKTLQALIEHHDALRMVY REENGDIVQVYKPIGESKVSFEIVDLYGSDEEMLRSQIKLLANKLQSSLDLRNGPLLK AEQYRTEAGDHLLIAVHHLVVDGVSWRILLEDFASGYMQAEKEESLVFPQKTNSFKDW AEELAAFSQSAHLLQQAEYWSQIAAEQVSPLPKDCETEQRIVKDTSSVLCELTAEDTK HLLTDVHQPYGTEINDILLSALGLTMKEWTKGAKIGINLEGHGREDIIPNVNISRTVG WFTAQYPVVLDISDADASAVIKTVKENLRRIPDKGVGYGILRYFTETAETKGFTPEIS FNYLGQFDSEVKTDFFEPSAFDMGRQVSGESEALYALSFSGMIRNGRFVLSCSYNEKE FERATVEEQMERFKENLLMLIRHCTEKEDKEFTPSDFSAEDLEMDEMGDIFDMLEENL K*" gene 387744..398495 /gene="srfAB" /locus_tag="BSU_03490" /old_locus_tag="BSU03490" CDS 390880..391020 /gene="comS" /locus_tag="BSU_03500" /old_locus_tag="BSU03500" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:10361283, 16554821, 8752331, 9696775, 22720735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10361283, 16554821, 8752331, 9696775, 22720735; Product type r: regulator" /codon_start=1 /transl_table=11 /product="regulator of genetic competence" /protein_id="NP_388232.1" /db_xref="EnsemblGenomes-Gn:BSU03500" /db_xref="EnsemblGenomes-Tr:CAB12144" /db_xref="GOA:P80355" /db_xref="InterPro:IPR035139" /db_xref="SubtiList:BG11045" /db_xref="UniProtKB/Swiss-Prot:P80355" /translation="MNRSGKHLISSIILYPRPSGECISSISLDKQTQATTSPLYFCWR EK*" gene 390880..391020 /gene="comS" /locus_tag="BSU_03500" /old_locus_tag="BSU03500" CDS 398532..402359 /gene="srfAC" /locus_tag="BSU_03510" /old_locus_tag="BSU03510" /function="16.8: Protect" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:15066026, 16166527, 16553878, 17227471, 14762003, 22720735, 26284661" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15066026, 16166527, 16553878, 17227471, 14762003, 22720735, 26284661; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="surfactin synthetase" /protein_id="NP_388233.2" /db_xref="EnsemblGenomes-Gn:BSU03510" /db_xref="EnsemblGenomes-Tr:CAB12145" /db_xref="GOA:Q08787" /db_xref="InterPro:IPR000873" /db_xref="InterPro:IPR001031" /db_xref="InterPro:IPR001242" /db_xref="InterPro:IPR006162" /db_xref="InterPro:IPR009081" /db_xref="InterPro:IPR010071" /db_xref="InterPro:IPR020806" /db_xref="InterPro:IPR020845" /db_xref="InterPro:IPR025110" /db_xref="InterPro:IPR029058" /db_xref="InterPro:IPR036736" /db_xref="PDB:1JMK" /db_xref="PDB:2VSQ" /db_xref="SubtiList:BG10170" /db_xref="UniProtKB/Swiss-Prot:Q08787" /translation="MSQFSKDQVQDMYYLSPMQEGMLFHAILNPGQSFYLEQITMKVK GSLNIKCLEESMNVIMDRYDVFRTVFIHEKVKRPVQVVLKKRQFHIEEIDLTHLTGSE QTAKINEYKEQDKIRGFDLTRDIPMRAAIFKKAEESFEWVWSYHHIILDGWCFGIVVQ DLFKVYNALREQKPYSLPPVKPYKDYIKWLEKQDKQASLRYWREYLEGFEGQTTFAEQ RKKQKDGYEPKELLFSLSEAETKAFTELAKSQHTTLSTALQAVWSVLISRYQQSGDLA FGTVVSGRPAEIKGVEHMVGLFINVVPRRVKLSEGITFNGLLKRLQEQSLQSEPHQYV PLYDIQSQADQPKLIDHIIVFENYPLQDAKNEESSENGFDMVDVHVFEKSNYDLNLMA SPGDEMLIKLAYNENVFDEAFILRLKSQLLTAIQQLIQNPDQPVSTINLVDDREREFL LTGLNPPAQAHETKPLTYWFKEAVNANPDAPALTYSGQTLSYRELDEEANRIARRLQK HGAGKGSVVALYTKRSLELVIGILGVLKAGAAYLPVDPKLPEDRISYMLADSAAACLL THQEMKEQAAELPYTGTTLFIDDQTRFEEQASDPATAIDPNDPAYIMYTSGTTGKPKG NITTHANIQGLVKHVDYMAFSDQDTFLSVSNYAFDAFTFDFYASMLNAARLIIADEHT LLDTERLTDLILQENVNVMFATTALFNLLTDAGEDWMKGLRCILFGGERASVPHVRKA LRIMGPGKLINCYGPTEGTVFATAHVVHDLPDSISSLPIGKPISNASVYILNEQSQLQ PFGAVGELCISGMGVSKGYVNRADLTKEKFIENPFKPGETLYRTGDLARWLPDGTIEY AGRIDDQVKIRGHRIELEEIEKQLQEYPGVKDAVVVADRHESGDASINAYLVNRTQLS AEDVKAHLKKQLPAYMVPQTFTFLDELPLTTNGKVNKRLLPKPDQDQLAEEWIGPRNE MEETIAQIWSEVLGRKQIGIHDDFFALGGHSLKAMTAASRIKKELGIDLPVKLLFEAP TIAGISAYLKNGGSDGLQDVTIMNQDQEQIIFAFPPVLGYGLMYQNLSSRLPSYKLCA FDFIEEEDRLDRYADLIQKLQPEGPLTLFGYSAGCSLAFEAAKKLEEQGRIVQRIIMV DSYKKQGVSDLDGRTVESDVEALMNVNRDNEALNSEAVKHGLKQKTHAFYSYYVNLIS TGQVKADIDLLTSGADFDMPEWLASWEEATTGVYRVKRGFGTHAEMLQGETLDRNAEI LLEFLNTQTVTVS*" gene 398532..402359 /gene="srfAC" /locus_tag="BSU_03510" /old_locus_tag="BSU03510" CDS 402388..403116 /gene="srfAD" /locus_tag="BSU_03520" /old_locus_tag="BSU03520" /function="16.8: Protect" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:16166527, 16553878, 17227471, 14762003, 22720735, 26284661" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16166527, 16553878, 17227471, 14762003, 22720735, 26284661; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="surfactin synthetase" /protein_id="NP_388234.1" /db_xref="EnsemblGenomes-Gn:BSU03520" /db_xref="EnsemblGenomes-Tr:CAB12146" /db_xref="GOA:Q08788" /db_xref="InterPro:IPR001031" /db_xref="InterPro:IPR012223" /db_xref="InterPro:IPR029058" /db_xref="PDB:2K2Q" /db_xref="PDB:2RON" /db_xref="SubtiList:BG10171" /db_xref="UniProtKB/Swiss-Prot:Q08788" /translation="MSQLFKSFDASEKTQLICFPFAGGYSASFRPLHAFLQGECEMLA AEPPGHGTNQTSAIEDLEELTDLYKQELNLRPDRPFVLFGHSMGGMITFRLAQKLERE GIFPQAVIISAIQPPHIQRKKVSHLPDDQFLDHIIQLGGMPAELVENKEVMSFFLPSF RSDYRALEQFELYDLAQIQSPVHVFNGLDDKKCIRDAEGWKKWAKDITFHQFDGGHMF LLSQTEEVAERIFAILNQHPIIQP*" gene 402388..403116 /gene="srfAD" /locus_tag="BSU_03520" /old_locus_tag="BSU03520" downshifts 403098 /Source="Nicolas_upshifts" /id="D154" /incds=0 /nref=196 /ntot=261 /MaxReadThrough="4.65721" /MaxDrop="6.48992" /score="24.9581454" /energy="-11.1" /TU="U268" /idTUdmin="U268" /TUdmin="-1339" /isTUend="FALSE" promotor_-35 403154..403161 /Source="Nicolas_upshift_promotors" /id="U269" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.795204795204795" /psig=1 /xcortree=2955 /SigmaFactorBS="cattcaaccgtgatcaaaagcggacagcttcggctgttccgc tttttttgTGTTGAATgccaatttctgCATGGTATAATAGTCGAAATactcaaataaa g" /listShort="ycxA" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 403164 /Source="Nicolas_upshifts" /id="U269" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.795204795204795" /psig=1 /xcortree=2955 /SigmaFactorBS="cattcaaccgtgatcaaaagcggacagcttcggctgttccgc tttttttgTGTTGAATgccaatttctgCATGGTATAATAGTCGAAATactcaaataaa g" /listShort="ycxA" /GFF_Attribute="listLong" promotor_-10 403173..403192 /Source="Nicolas_upshift_promotors" /id="U269" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.795204795204795" /psig=1 /xcortree=2955 /SigmaFactorBS="cattcaaccgtgatcaaaagcggacagcttcggctgttccgc tttttttgTGTTGAATgccaatttctgCATGGTATAATAGTCGAAATactcaaataaa g" /listShort="ycxA" /GFF_Attribute="listLong" /label="promotor_-10" CDS 403217..404443 /gene="srfT" /locus_tag="BSU_03530" /old_locus_tag="BSU03530" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1b: Function from experimental evidences in the studied species; PubMedId: 15849754, 16850406, 25366377; Product type t: transporter" /codon_start=1 /transl_table=11 /product="surfactin exporter" /protein_id="NP_388235.2" /db_xref="EnsemblGenomes-Gn:BSU03530" /db_xref="EnsemblGenomes-Tr:CAB12147" /db_xref="GOA:Q08791" /db_xref="InterPro:IPR011701" /db_xref="InterPro:IPR020846" /db_xref="InterPro:IPR036259" /db_xref="SubtiList:BG10172" /db_xref="UniProtKB/Swiss-Prot:Q08791" /translation="MRTSPRMKWFVLLFTFVFAIGMNSFRNSFQFFMLPMADAFHADR SLISVSVSIFMITTGIVQFFVGFFIDRFSVRKIMALGAVCISASFLVLPYSPNVHVFS AIYGVLGGIGYSCAVGVTTQYFISCWFDTHKGLALAILTNANSAGLLLLSPIWAAAPY HAGWQSTYTILGIVMAAVLLPLLVFGMKHPPHAQAETVKKSYDWRGFWNVMKQSRLIH ILYFGVFTCGFTMGIIDAHLVPILKDAHVSHVNGMMAAFGAFIIIGGLLAGWLSDLLG SRSVMLSILFFIRLLSLICLLIPILGIHHSDLWYFGFILLFGLSYTGVIPLTAASISE SYQTGLIGSLLGINFFIHQVAGALSVYAGGLFFDMTHGYLLIVAVCIVFVGLSAVIEL VPFLDKQKAKETHHSI*" gene 403217..404443 /gene="srfT" /locus_tag="BSU_03530" /old_locus_tag="BSU03530" downshifts 404437 /Source="Nicolas_upshifts" /id="D155" /incds=0 /nref=15 /ntot=198 /MaxReadThrough="2.67601" /MaxDrop="4.06773" /score="7.33278866" /energy="-13.2" /TU="NA" /idTUdmin="U268" /TUdmin=0 /isTUend="TRUE" CDS complement(404458..405015) /gene="ycxB" /locus_tag="BSU_03540" /old_locus_tag="BSU03540" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function; PubMedId : 21965396" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="NP_388236.1" /db_xref="EnsemblGenomes-Gn:BSU03540" /db_xref="EnsemblGenomes-Tr:CAB12148" /db_xref="GOA:Q08793" /db_xref="InterPro:IPR025588" /db_xref="SubtiList:BG10173" /db_xref="UniProtKB/Swiss-Prot:Q08793" /translation="MIQYASESINLPGEITFKDVREIFFYQIAKISCFYFLLFCAIFA AVNFINGWPRIVYGSDALNLFMNSMLIIVMSVLFTLLLLLLLYVKFSRAYKKNERMKS KRTYTLNQEGIRICSKKYDLIFNWDEITAVFEYKNIFRVNTSSGQYIAIPKHFFHSEE EMNRFKEIILKNTETKKLKFKKDQH*" gene complement(404458..405015) /gene="ycxB" /locus_tag="BSU_03540" /old_locus_tag="BSU03540" promotor_no_box complement(404473..404573) /Source="Nicolas_upshift_promotors" /id="U270" /multdbtbs="-" /comp="M21" /sig="Sig-" /pcomp="0.725274725274725" /psig="0.024975024975025" /xcortree=283 /SigmaFactorBS="atattgcgatccccaaacatttttttcactccgaagaggaga tgaacagattcaaggagattatccttaaaaataccgaaacaaaaaaactcaaatttaa a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_no_box" downshifts complement(404495) /Source="Nicolas_upshifts" /id="D156" /incds=0 /nref=46 /ntot=241 /MaxReadThrough="0.9216" /MaxDrop="4.25654" /score="8.42655219" /energy="-14.3" /TU="U270" /idTUdmin="U271" /TUdmin=18 /isTUend="TRUE" upshifts complement(404513) /Source="Nicolas_upshifts" /id="U270" /multdbtbs="-" /comp="M21" /sig="Sig-" /pcomp="0.725274725274725" /psig="0.024975024975025" /xcortree=283 /SigmaFactorBS="atattgcgatccccaaacatttttttcactccgaagaggaga tgaacagattcaaggagattatccttaaaaataccgaaacaaaaaaactcaaatttaa a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" misc_feature complement(405044..405063) /Source="Nicolas_upshift_promotors" /id="U271" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.942057942057942" /psig=1 /xcortree=3105 /SigmaFactorBS="aaaaaacaaagcgccctggtatgcctgcaaaaaaatgagaaa tTATGCTAGACTAAAAGGAAAaacatggttagaggtgtaggtttaccgtatgattcaa t" /listShort="ycxB" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(405046) /Source="Nicolas_upshifts" /id="U271" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.942057942057942" /psig=1 /xcortree=3105 /SigmaFactorBS="aaaaaacaaagcgccctggtatgcctgcaaaaaaatgagaaa tTATGCTAGACTAAAAGGAAAaacatggttagaggtgtaggtttaccgtatgattcaa t" /listShort="ycxB" /GFF_Attribute="listLong" CDS complement(405069..406007) /gene="ycxC" /locus_tag="BSU_03550" /old_locus_tag="BSU03550" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative permease" /protein_id="NP_388237.2" /db_xref="EnsemblGenomes-Gn:BSU03550" /db_xref="EnsemblGenomes-Tr:CAB12149" /db_xref="GOA:Q08794" /db_xref="InterPro:IPR000620" /db_xref="SubtiList:BG10174" /db_xref="UniProtKB/Swiss-Prot:Q08794" /translation="MVKHQQTPAYIAAILYSFIIGLSFLFVKIALQTAEPFDILAHRF TIAFAAATVPILFGWVKLSIRVKDVIDILPLALLYPALFFSFQAFGLVYSSSSEAGII QAAIPIFTMVFAAYVLKERPTWTQKGFTVLSVAGVMFIFVMKGVDVESASLKGSLLIL LSALSSAMYNTAARKMTQRFKLTELTYIMSAIGFVVFNAIALVRHGAAGTVGTYFLPF REPGFVLAIVYLGVLSSLVTSFLSNYTLSRIEAFKMSAFNHVSTIVTMIAGFVILNES LAWYHLAGAVCIMIGVVGSNINLEKKTKRPGMPAKK*" gene complement(405069..406007) /gene="ycxC" /locus_tag="BSU_03550" /old_locus_tag="BSU03550" promotor_-10 complement(406046..406064) /Source="Nicolas_upshift_promotors" /id="U272" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.536463536463537" /psig="0.536463536463537" /xcortree=793 /SigmaFactorBS="tgtaccggtacagttcattgtttttctcATTGTAccgttctg accgcggCCATACAATAAAGGGAGCGaccggcgctgcaattcaggtaaaggagccctt c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(406053) /Source="Nicolas_upshifts" /id="U272" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.536463536463537" /psig="0.536463536463537" /xcortree=793 /SigmaFactorBS="tgtaccggtacagttcattgtttttctcATTGTAccgttctg accgcggCCATACAATAAAGGGAGCGaccggcgctgcaattcaggtaaaggagccctt c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(406080..406085) /Source="Nicolas_upshift_promotors" /id="U272" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.536463536463537" /psig="0.536463536463537" /xcortree=793 /SigmaFactorBS="tgtaccggtacagttcattgtttttctcATTGTAccgttctg accgcggCCATACAATAAAGGGAGCGaccggcgctgcaattcaggtaaaggagccctt c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" CDS 406131..407465 /gene="ycxD" /locus_tag="BSU_03560" /old_locus_tag="BSU03560" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15223311, 26585522; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative PLP-dependent transcriptional regulator" /protein_id="NP_388238.1" /db_xref="EnsemblGenomes-Gn:BSU03560" /db_xref="EnsemblGenomes-Tr:CAB12150" /db_xref="GOA:Q08792" /db_xref="InterPro:IPR000524" /db_xref="InterPro:IPR004839" /db_xref="InterPro:IPR015421" /db_xref="InterPro:IPR015422" /db_xref="InterPro:IPR015424" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG10175" /db_xref="UniProtKB/Swiss-Prot:Q08792" /translation="MEKYMSLLTRIEEMMQSTSYQEGDRLPSIRQLSARYQVSKSTVI RALQELEKRHLIYSVPKSGYYIVKKSGKSKSGQPGPIDFATSAPDPDVFPYLDFQHCI NKAIDTYKNDLFIYGTPKGLPSLIRVLRKLLATQQVFADERHIFITSGVQQALSLLCA MPFPNGKEKIAIEQPGYHLMVEQLETLGIPAIGVKRTEEGLDIAKVERLFQTESIKFF YTMPRFHNPLGCSLSERDKQELVRLAEAYDVYLVEDDYLGDLEENKKADPLYAYDLSS HVIYLKSFSKMMFPGLRVGAAVLPEALTDTFYAYKKLNDIDCSMISQAALEIYLKSGM YGRHKEKIRDSYKERSLRLHQAIRTHRQLGSGRFTFSSGQAPCMHTHLVLPQDLPASR VIHRLEKQGVLLEAIDRHYLSDYPKENLLKINISNVKTEDIERGVKLLMSHL*" gene 406131..407465 /gene="ycxD" /locus_tag="BSU_03560" /old_locus_tag="BSU03560" CDS complement(407460..407627) /gene="sfpAc" /locus_tag="BSU_03569" /old_locus_tag="BSU03569" /EC_number="2.7.8.-" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1b: Function from experimental evidences in the studied species; PubMedId: 10568751, 17376553, 2848009, 9384377, 14762003, 16707694, 19061923, 20971906, 25288929, 26268540; Product type e: enzyme" /pseudo /codon_start=1 /transl_table=11 /product="C-terminal part of 4'-phosphopantetheinyl transferase (Surfactin synthetase-activating enzyme)" /db_xref="PSEUDO:CAX52545.1" /translation="MRLHQDGQVSIELPDSHSPCYIKTYEVDPGYKMAVCAVHPDFPE DITMVSYEELL*" gene complement(407460..407627) /gene="sfpAc" /locus_tag="BSU_03569" /old_locus_tag="BSU03569" /pseudo CDS complement(407638..408135) /gene="sfpAn" /locus_tag="BSU_03570" /old_locus_tag="BSU03570" /EC_number="2.7.8.-" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1b: Function from experimental evidences in the studied species; PubMedId: 10568751, 17376553, 2848009, 9384377, 14762003, 16707694, 19061923, 20971906, 25288929, 26268540; Product type e: enzyme" /pseudo /codon_start=1 /transl_table=11 /product="N-terminal part of 4'-phosphopantetheinyl transferase (surfactin synthetase-activating enzyme)" /db_xref="GOA:P39135" /db_xref="InterPro:IPR004568" /db_xref="InterPro:IPR008278" /db_xref="InterPro:IPR037143" /db_xref="PDB:1QR0" /db_xref="PDB:2GE0" /db_xref="PDB:2GE1" /db_xref="PDB:4MRT" /db_xref="PSEUDO:CAB12151.2" /db_xref="SubtiList:BG10176" /db_xref="UniProtKB/Swiss-Prot:P39135" /translation="MKIYGIYMDRPLSQEENERFMSFISPEKREKCRRFYHKEDAHRT LLGDVLVRSVISRQYQLDKSDIRFSTQEYGKPCIPDLPDAHFNISHSGRWVICAFDSQ PIGIDIEKTKPISLEIAKRFFSKTEYSDLLAKDKDEQTDYFYHLWSMKESFIKQGRQR LIASA*" gene complement(407638..408135) /gene="sfpAn" /locus_tag="BSU_03570" /old_locus_tag="BSU03570" /pseudo misc_feature complement(408162..408181) /Source="Nicolas_upshift_promotors" /id="U273" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.984015984015984" /psig=1 /xcortree=2243 /SigmaFactorBS="agccgccttggctttgtttttttattttctcctctatatgag tcttgtggaagTATGATAGGATGGTTTTGACaatcttttgcagacggaggatctagaa t" /listShort="sfp, sfp" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(408174) /Source="Nicolas_upshifts" /id="U273" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.984015984015984" /psig=1 /xcortree=2243 /SigmaFactorBS="agccgccttggctttgtttttttattttctcctctatatgag tcttgtggaagTATGATAGGATGGTTTTGACaatcttttgcagacggaggatctagaa t" /listShort="sfp, sfp" /GFF_Attribute="listLong" CDS complement(408240..408887) /gene="yczE" /locus_tag="BSU_03580" /old_locus_tag="BSU03580" /function="15.11: Biosynthesis of natural products" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 15849754, 16850406, 17827323, 14762003, 16707694, 17827323, 25288929; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="integral inner membrane protein regulating antibiotic production" /protein_id="NP_388240.2" /db_xref="EnsemblGenomes-Gn:BSU03580" /db_xref="EnsemblGenomes-Tr:CAB12152" /db_xref="GOA:O34927" /db_xref="SubtiList:BG12779" /db_xref="UniProtKB/Swiss-Prot:O34927" /translation="MKQELVLRWTFYFAGLIILAFGVSLTIEGKALGISPWDAFHYSL FQHFGLTVGQWSIIIGALIVGFTSLFTRAWPKIGALLNMVLIGVFIDFFNFILPALST YTGSIIVFSLGVVLIGYGVGVYVSAGLGAGPRDSLMMLITEKTGWNVQWVRNGMELTI LFAAWGMGGPIGFGTILTAILTGLILRFSLPQSIQLLNYAVARRTAAVKASPPVH*" gene complement(408240..408887) /gene="yczE" /locus_tag="BSU_03580" /old_locus_tag="BSU03580" promotor_-10 complement(408916..408935) /Source="Nicolas_upshift_promotors" /id="U274" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.866133866133866" /psig=1 /xcortree=2616 /SigmaFactorBS="tttttttgttgagcccctttcgccTATTCcgcccttctgtca gaTGTGCTACAATGACAATCGActgatttttacgaaagaagggacctcacgtgaagca a" /listShort="yczE, sfp, sfp" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(408919) /Source="Nicolas_upshifts" /id="U274" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.866133866133866" /psig=1 /xcortree=2616 /SigmaFactorBS="tttttttgttgagcccctttcgccTATTCcgcccttctgtca gaTGTGCTACAATGACAATCGActgatttttacgaaagaagggacctcacgtgaagca a" /listShort="yczE, sfp, sfp" /GFF_Attribute="listLong" promotor_-35 complement(408951..408955) /Source="Nicolas_upshift_promotors" /id="U274" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.866133866133866" /psig=1 /xcortree=2616 /SigmaFactorBS="tttttttgttgagcccctttcgccTATTCcgcccttctgtca gaTGTGCTACAATGACAATCGActgatttttacgaaagaagggacctcacgtgaagca a" /listShort="yczE, sfp, sfp" /GFF_Attribute="listLong" /label="promotor_-35" S_feature complement(409056..409207) /Source="Nicolas_S_feature" /locus_tag="new_409056_409207_c" /HighExp="G180, G135, dia15, H2O2, Diami, S8, Oxctl, G150, LPhT, Heat" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="NA" /TUshortPSig="NA" /TUlongSig="NA" /TUlongPSig="NA" /label="S127" CDS complement(409208..409951) /gene="tcyC" /locus_tag="BSU_03590" /old_locus_tag="BSU03590" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:15262924, 16513748, 22212096" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15262924, 16513748, 22212096; Product type t: transporter" /codon_start=1 /transl_table=11 /product="cystine ABC transporter (ATP-binding protein)" /protein_id="NP_388241.2" /db_xref="EnsemblGenomes-Gn:BSU03590" /db_xref="EnsemblGenomes-Tr:CAB12153" /db_xref="GOA:P39456" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR017871" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR030679" /db_xref="SubtiList:BG11185" /db_xref="UniProtKB/Swiss-Prot:P39456" /translation="MLTVKGLNKSFGENEILKKIDMKIEKGKVIAILGPSGSGKTTLL RCLNALEIPNRGELAFDDFSIDFSKKVKQADILKLRRKSGMVFQAYHLFPHRTALENV MEGPVQVQKRNKEEVRKEAIQLLDKVGLKDKMDLYPFQLSGGQQQRVGIARALAIQPE LMLFDEPTSALDPELVGEVLKVIKDLANEGWTMVVVTHEIKFAQEVADEVIFIDGGVI VEQGPPEQIFSAPKEERTQRFLNRILNPL*" gene complement(409208..409951) /gene="tcyC" /locus_tag="BSU_03590" /old_locus_tag="BSU03590" downshifts complement(409264) /Source="Nicolas_upshifts" /id="D157" /incds=0 /nref=72 /ntot=232 /MaxReadThrough="4.60958" /MaxDrop="4.44283" /score="1.62131565" /energy="-12.6" /TU="U275" /idTUdmin="U276" /TUdmin=4 /isTUend="TRUE" CDS complement(409965..410669) /gene="tcyB" /locus_tag="BSU_03600" /old_locus_tag="BSU03600" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:15262924, 15849754, 16850406, 22212096" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15262924, 15849754, 16850406, 22212096; Product type t: transporter" /codon_start=1 /transl_table=11 /product="cystine ABC transporter (permease)" /protein_id="NP_388242.1" /db_xref="EnsemblGenomes-Gn:BSU03600" /db_xref="EnsemblGenomes-Tr:CAB12154" /db_xref="GOA:P42200" /db_xref="InterPro:IPR000515" /db_xref="InterPro:IPR010065" /db_xref="InterPro:IPR035906" /db_xref="SubtiList:BG11186" /db_xref="UniProtKB/Swiss-Prot:P42200" /translation="MFLNNLPALTLGTAIPWDLVQQSFWPILSGGIYYTIPLTILSFI FGMILALITALARMSKVRPLRWVFSVYVSAIRGTPLLVQLFIIFYLFPAFNVTLDPFP SAVIAFSLNVGAYASEIIRASILSVPKGQWEAGYTIGMTHQKTLFRVILPQAFRVSIP PLSNTFISLIKDTSLASQILVAELFRKAQEIGARNLDQILVIYIEAAFIYWIICFLLS LVQHVIERRLDRYVAK*" gene complement(409965..410669) /gene="tcyB" /locus_tag="BSU_03600" /old_locus_tag="BSU03600" CDS complement(410656..411462) /gene="tcyA" /locus_tag="BSU_03610" /old_locus_tag="BSU03610" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:15262924, 22212096" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15262924, 22212096; Product type t: transporter" /codon_start=1 /transl_table=11 /product="cystine ABC transporter (substrate-binding lipoprotein)" /protein_id="NP_388243.2" /db_xref="EnsemblGenomes-Gn:BSU03610" /db_xref="EnsemblGenomes-Tr:CAB12155" /db_xref="GOA:P42199" /db_xref="InterPro:IPR001638" /db_xref="InterPro:IPR018313" /db_xref="SubtiList:BG11187" /db_xref="UniProtKB/Swiss-Prot:P42199" /translation="MKKALLALFMVVSIAALAACGAGNDNQSKDNAKDGDLWASIKKK GVLTVGTEGTYEPFTYHDKDTDKLTGYDVEVITEVAKRLGLKVDFKETQWDSMFAGLN SKRFDVVANQVGKTDREDKYDFSDKYTTSRAVVVTKKDNNDIKSEADVKGKTSAQSLT SNYNKLATNAGAKVEGVEGMAQALQMIQQGRVDMTYNDKLAVLNYLKTSGNKNVKIAF ETGEPQSTYFTFRKGSGEVVDQVNKALKEMKEDGTLSKISKKWFGEDVSK*" gene complement(410656..411462) /gene="tcyA" /locus_tag="BSU_03610" /old_locus_tag="BSU03610" promotor_-10 complement(411511..411530) /Source="Nicolas_upshift_promotors" /id="U275" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.913086913086913" /psig="0.987012987012987" /xcortree=1798 /SigmaFactorBS="ttttaaaagattttgtcttatgaaaaccaaatACTTGACTca tactaaaaaaaAGTTATCCTTTAGATTTGTAagctaattttttatttcaataaaatca a" /listShort="tcyA, tcyB, tcyC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(411523) /Source="Nicolas_upshifts" /id="U275" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.913086913086913" /psig="0.987012987012987" /xcortree=1798 /SigmaFactorBS="ttttaaaagattttgtcttatgaaaaccaaatACTTGACTca tactaaaaaaaAGTTATCCTTTAGATTTGTAagctaattttttatttcaataaaatca a" /listShort="tcyA, tcyB, tcyC" /GFF_Attribute="listLong" promotor_-35 complement(411544..411551) /Source="Nicolas_upshift_promotors" /id="U275" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.913086913086913" /psig="0.987012987012987" /xcortree=1798 /SigmaFactorBS="ttttaaaagattttgtcttatgaaaaccaaatACTTGACTca tactaaaaaaaAGTTATCCTTTAGATTTGTAagctaattttttatttcaataaaatca a" /listShort="tcyA, tcyB, tcyC" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(411578..412450) /gene="bsdA" /locus_tag="BSU_03620" /old_locus_tag="BSU03620" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:17295427" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 17295427; Product type r: regulator" /codon_start=1 /transl_table=11 /product="HTH-type transcriptional regulator BsdA (LysR family)" /protein_id="NP_388244.1" /db_xref="EnsemblGenomes-Gn:BSU03620" /db_xref="EnsemblGenomes-Tr:CAB12156" /db_xref="GOA:P94403" /db_xref="InterPro:IPR000847" /db_xref="InterPro:IPR005119" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG12022" /db_xref="UniProtKB/Swiss-Prot:P94403" /translation="MDIRQLRYFITIAQEQKITSAAKKLHMAQPPLSRQLKQLEDELG VVLFDRNKKKQMTLTYEGAVFLKRAKEILHRFEDAVIEVQELKEEVAGTLAVGSTIYC AALMLEKVTQIKERYPHLTFNIWENEPATLLELLESRQIDAAVTTTLIKSDTVQFKQL DDIPCVLVLSDEAGYPCGDTIKMVDIPSFPLILLRPVNGKGVYNQVMNEFHRLNLEPR IVCECHDSATLLSLVSSGFGASILPVTMIPVHMRNHVHTVHIENNPFIMTPAVMWRTD SYLPKPAQQFLDLF*" gene complement(411578..412450) /gene="bsdA" /locus_tag="BSU_03620" /old_locus_tag="BSU03620" promotor_-10 complement(412188..412206) /Source="Nicolas_upshift_promotors" /id="U276" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=148 /SigmaFactorBS="ctaaaaagagcaaaagagattctgcataGGTTTGAagatgca gtcattgAGGTACAGGAGCTGAAGGAggaagtagccggtacacttgccgtgggatcaa c" /listShort="tcyA, tcyB, tcyC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(412195) /Source="Nicolas_upshifts" /id="U276" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=148 /SigmaFactorBS="ctaaaaagagcaaaagagattctgcataGGTTTGAagatgca gtcattgAGGTACAGGAGCTGAAGGAggaagtagccggtacacttgccgtgggatcaa c" /listShort="tcyA, tcyB, tcyC" /GFF_Attribute="listLong" promotor_-35 complement(412221..412227) /Source="Nicolas_upshift_promotors" /id="U276" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=148 /SigmaFactorBS="ctaaaaagagcaaaagagattctgcataGGTTTGAagatgca gtcattgAGGTACAGGAGCTGAAGGAggaagtagccggtacacttgccgtgggatcaa c" /listShort="tcyA, tcyB, tcyC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 412504..412511 /Source="Nicolas_upshift_promotors" /id="U278" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.947052947052947" /psig="0.97902097902098" /xcortree=1580 /SigmaFactorBS="ccttttaggtattaattatagatttaatagaTATTTTTCata tggatatatcAGGAGTATGATTGAAATGAAagcagaattcaagcgtaaaggagggggc a" /listShort="ubiX, ubiD, bsdD, yclD" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(412519..412538) /Source="Nicolas_upshift_promotors" /id="U277" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.978021978021978" /psig="0.985014985014985" /xcortree=1966 /SigmaFactorBS="cgagtttcactttgccccctcctttaCGCTTGAAttctgctt tcattTCAATCATACTCCTGATATAtccatatgaaaaatatctattaaatctataatt a" /listShort="yclA" /listLong="tcyA, tcyB, tcyC" /label="promotor_-10" promotor_-10 412525..412544 /Source="Nicolas_upshift_promotors" /id="U278" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.947052947052947" /psig="0.97902097902098" /xcortree=1580 /SigmaFactorBS="ccttttaggtattaattatagatttaatagaTATTTTTCata tggatatatcAGGAGTATGATTGAAATGAAagcagaattcaagcgtaaaggagggggc a" /listShort="ubiX, ubiD, bsdD, yclD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(412525) /Source="Nicolas_upshifts" /id="U277" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.978021978021978" /psig="0.985014985014985" /xcortree=1966 /SigmaFactorBS="cgagtttcactttgccccctcctttaCGCTTGAAttctgctt tcattTCAATCATACTCCTGATATAtccatatgaaaaatatctattaaatctataatt a" /listShort="yclA" /listLong="tcyA, tcyB, tcyC" upshifts 412533 /Source="Nicolas_upshifts" /id="U278" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.947052947052947" /psig="0.97902097902098" /xcortree=1580 /SigmaFactorBS="ccttttaggtattaattatagatttaatagaTATTTTTCata tggatatatcAGGAGTATGATTGAAATGAAagcagaattcaagcgtaaaggagggggc a" /listShort="ubiX, ubiD, bsdD, yclD" /GFF_Attribute="listLong" CDS 412540..413154 /gene="ubiX" /locus_tag="BSU_03630" /old_locus_tag="BSU03630" /EC_number="4.1.1.-" /EC_number="4.1.1.61" /function="3.2: Degradation" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1b: Function from experimental evidences in the studied species; PubMedId: 10919793, 15979273, 17295427, 18388975, 26083743, 26658822, 26337367; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="phenolic acid decarboxylase-flavin prenyltransferase subunit" /protein_id="NP_388245.1" /db_xref="EnsemblGenomes-Gn:BSU03630" /db_xref="EnsemblGenomes-Tr:CAB12157" /db_xref="GOA:P94404" /db_xref="InterPro:IPR003382" /db_xref="InterPro:IPR004507" /db_xref="InterPro:IPR032901" /db_xref="InterPro:IPR036551" /db_xref="SubtiList:BG12023" /db_xref="UniProtKB/Swiss-Prot:P94404" /translation="MKAEFKRKGGGKVKLVVGMTGATGAIFGVRLLQWLKAAGVETHL VVSPWANVTIKHETGYTLQEVEQLATYTYSHKDQAAAISSGSFDTDGMIVAPCSMKSL ASIRTGMADNLLTRAADVMLKERKKLVLLTRETPLNQIHLENMLALTKMGTIILPPMP AFYNRPRSLEEMVDHIVFRTLDQFGIRLPEAKRWNGIEKQKGGA*" gene 412540..413154 /gene="ubiX" /locus_tag="BSU_03630" /old_locus_tag="BSU03630" promotor_-35 complement(412552..412559) /Source="Nicolas_upshift_promotors" /id="U277" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.978021978021978" /psig="0.985014985014985" /xcortree=1966 /SigmaFactorBS="cgagtttcactttgccccctcctttaCGCTTGAAttctgctt tcattTCAATCATACTCCTGATATAtccatatgaaaaatatctattaaatctataatt a" /listShort="yclA" /listLong="tcyA, tcyB, tcyC" /label="promotor_-35" CDS 413157..414578 /gene="bsdC" /locus_tag="BSU_03640" /old_locus_tag="BSU03640" /EC_number="4.1.1.61" /EC_number="4.1.1.-" /function="3.2: Degradation" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1b: Function from experimental evidences in the studied species; PubMedId: 11029449, 15979273, 17295427, 18388975, 26658822, 26337367; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="promiscuous phenolic acid decarboxylase subunit;1,4-dihydroxy-2-naphtoate-heptaprenyl diphosphatedecarboxylase" /protein_id="NP_388246.1" /db_xref="EnsemblGenomes-Gn:BSU03640" /db_xref="EnsemblGenomes-Tr:CAB12158" /db_xref="GOA:P94405" /db_xref="InterPro:IPR002830" /db_xref="InterPro:IPR012349" /db_xref="InterPro:IPR032902" /db_xref="SubtiList:BG12024" /db_xref="UniProtKB/Swiss-Prot:P94405" /translation="MAYQDFREFLAALEKEGQLLTVNEEVKPEPDLGASARAASNLGD KSPALLFNNIYGYHNARIAMNVIGSWPNHAMMLGMPKDTPVKEQFFEFAKRYDQFPMP VKREETAPFHENEITEDINLFDILPLFRINQGDGGYYLDKACVISRDLEDPDNFGKQN VGIYRMQVKGKDRLGIQPVPQHDIAIHLRQAEERGINLPVTIALGCEPVITTAASTPL LYDQSEYEMAGAIQGEPYRIVKSKLSDLDVPWGAEVVLEGEIIAGEREYEGPFGEFTG HYSGGRSMPIIKIKRVYHRNNPIFEHLYLGMPWTECDYMIGINTCVPLYQQLKEAYPN EIVAVNAMYTHGLIAIVSTKTRYGGFAKAVGMRALTTPHGLGYCKMVIVVDEDVDPFN LPQVMWALSTKMHPKHDAVIIPDLSVLPLDPGSNPSGITHKMILDATTPVAPETRGHY SQPLDSPLTTKEWEQKLMDLMNK*" gene 413157..414578 /gene="bsdC" /locus_tag="BSU_03640" /old_locus_tag="BSU03640" CDS 414595..414822 /gene="bsdD" /locus_tag="BSU_03651" /old_locus_tag="BSU03651" /EC_number="4.1.1.91" /EC_number="4.1.1.-" /EC_number="4.1.1.61" /function="3.2: Degradation" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1b: Function from experimental evidences in the studied species; PubMedId: 15979273, 17295427, 18388975, 26658822; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="phenolic acid decarboxylase subunit" /protein_id="YP_003097675.1" /db_xref="EnsemblGenomes-Gn:BSU03651" /db_xref="EnsemblGenomes-Tr:CAX52546" /db_xref="GOA:C0H3U9" /db_xref="UniProtKB/Swiss-Prot:C0H3U9" /translation="MHTCPRCDSKKGEVMSKSPVEGAWEVYQCQTCFFTWRSCEPESI TNPEKYNPAFKIDPKETETAIEVPAVPERKA*" gene 414595..414822 /gene="bsdD" /locus_tag="BSU_03651" /old_locus_tag="BSU03651" CDS 414819..415283 /gene="yclD" /locus_tag="BSU_03652" /old_locus_tag="BSU03652" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15979273, 18388975; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative FMN-binding enzyme subunit" /protein_id="NP_388247.2" /db_xref="EnsemblGenomes-Gn:BSU03652" /db_xref="EnsemblGenomes-Tr:CAB12159" /db_xref="GOA:C0SPB5" /db_xref="InterPro:IPR012349" /db_xref="SubtiList:BG12025" /db_xref="UniProtKB/Swiss-Prot:C0SPB5" /translation="MIRVNCMSDRLFELLDGSCLNEKQHEAFVLQTVSEDGWPHAAMI SAGEIIALSRTDIRIALWKNTMTSANILRTGKAQFTAWWKGAAYYVKLECAPLPPLKD AEYERDRFSCRIVSVKEDVAKYADLTSGVRIQLHSPEEVLSRWKKTLEDLKR*" gene 414819..415283 /gene="yclD" /locus_tag="BSU_03652" /old_locus_tag="BSU03652" downshifts 415264 /Source="Nicolas_upshifts" /id="D158" /incds=0 /nref=1 /ntot=4 /MaxReadThrough="3.32586" /MaxDrop="3.88166" /score="45.8937489" /energy="-15.1" /TU="NA" /idTUdmin="U278" /TUdmin=0 /isTUend="TRUE" misc_feature 415290..415291 /Source="Nicolas_upshift_promotors" /id="U279" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.357642357642358" /psig="0.557442557442557" /xcortree=3132 /SigmaFactorBS="ctgaagaggtgctgagcagatggaaaaagaccctggaagatt taaaacggtaatatcgaTAgcctgacgccatgcgtcaggctttttttatataatgaaa a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 415291 /Source="Nicolas_upshifts" /id="U279" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.357642357642358" /psig="0.557442557442557" /xcortree=3132 /SigmaFactorBS="ctgaagaggtgctgagcagatggaaaaagaccctggaagatt taaaacggtaatatcgaTAgcctgacgccatgcgtcaggctttttttatataatgaaa a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" CDS 415350..416195 /gene="yclE" /locus_tag="BSU_03660" /old_locus_tag="BSU03660" /function="16.6: Maintain" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative hydrolase" /protein_id="NP_388248.2" /db_xref="EnsemblGenomes-Gn:BSU03660" /db_xref="EnsemblGenomes-Tr:CAB12160" /db_xref="GOA:P94407" /db_xref="InterPro:IPR000073" /db_xref="InterPro:IPR029058" /db_xref="SubtiList:BG12026" /db_xref="UniProtKB/Swiss-Prot:P94407" /translation="MERAGICHSDGFDLAYRIEGEGAPILVIGSAVYYPRLFSSDIKQ KYQWVFVDHRGFAKPKRELRAEDSRLDAVLADIERMRTFLQLEDVTILGHSGHAFMAL EYARTYPKQVRKVALFNTAPDNSEERQRKSESFFMETASLERKKRFEKDIENLPQDID KDPERRFVHMCIRAEAKSFYQERPHAAALWDGVFTNMPIIDELWGNTFARIDLLQRLA DVRMPVYIGLGRYDYLVAPVSLWDAVDGLYPHVDKVIFEKSGHQPMLEEPEAFDQSFR KWLDQ*" gene 415350..416195 /gene="yclE" /locus_tag="BSU_03660" /old_locus_tag="BSU03660" CDS complement(416235..417713) /gene="dtpT" /locus_tag="BSU_03670" /old_locus_tag="BSU03670" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 8458848, 11717292, 15849754, 16204487, 16850406, 17496096, 23144141, 25966844; Product type t: transporter" /codon_start=1 /transl_table=11 /product="di-tripeptide-proton ABC symporter" /protein_id="NP_388249.2" /db_xref="EnsemblGenomes-Gn:BSU03670" /db_xref="EnsemblGenomes-Tr:CAB12175" /db_xref="GOA:P94408" /db_xref="InterPro:IPR000109" /db_xref="InterPro:IPR005279" /db_xref="InterPro:IPR018456" /db_xref="InterPro:IPR020846" /db_xref="InterPro:IPR036259" /db_xref="SubtiList:BG12027" /db_xref="UniProtKB/Swiss-Prot:P94408" /translation="MASIDNESIIKSVPQKGFFGHPRGLFTLFFTEFWERFSYYGMRA ILLYYLYTETVNGGLGFDKGTAVAIMSIYGSLVYMSTIIGGWLADRVFGTANTVFYGG IFIMFGHIALAYPGSSIAFYISMVLIIVGTGLLKPNVSSVVGDLYTKEDPRRDSGFSI FYMGINLGGLLAPLIVGTLGQKYNYHLGFGAAAVGMLLGLIVFALTRKKNLGLAGSNV PNPLSKKSAIGTGIGVIIVAIAVIISVQTGVLTIKRFIDLVSILGILIPVIYFIIMFT SKKADKTEKSRLAAYVPLFIGAVMFWAIQEQGATILAVYADERIRLSLGGFELQSSWF QSLNPLFVVIFAPIFAWLWMKLGKRQPSTPVKFSIGIILAGLSFIIMVFPAMQGKEAL VSPLWLVLSFLLVVLGELCLSPVGLSVTTKLAPAAFSAQTMSMWFLTNAAAQAINAQV AGLFDKIPETMYFGTIGLISIVLGGILLLLSPVIKRAMKGVL*" gene complement(416235..417713) /gene="dtpT" /locus_tag="BSU_03670" /old_locus_tag="BSU03670" downshifts complement(416243) /Source="Nicolas_upshifts" /id="D159" /incds=0 /nref=17 /ntot=90 /MaxReadThrough="1.40624" /MaxDrop="3.91827" /score="43.5753464" /energy="-21" /TU="NA" /idTUdmin="U281" /TUdmin=0 /isTUend="TRUE" promotor_-35 417740..417742 /Source="Nicolas_upshift_promotors" /id="U280" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.257742257742258" /psig="0.581418581418581" /xcortree=1444 /SigmaFactorBS="ctttcgttatcaatcgaagccatgtcagccaaaccctttcta aaaaaagTGTattataaaaatcatatTCTTATATAATACTTGTGTcaatataatttat a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(417741..417760) /Source="Nicolas_upshift_promotors" /id="U281" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.936063936063936" /psig="0.97002997002997" /xcortree=1442 /SigmaFactorBS="tttttccaatatggaactatttgaaatgagtataaattaTAT TGACAcaagtattatataaGAATATGATTTTTATAATACactttttttagaaagggtt t" /listShort="dtpT" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 417751 /Source="Nicolas_upshifts" /id="U280" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.257742257742258" /psig="0.581418581418581" /xcortree=1444 /SigmaFactorBS="ctttcgttatcaatcgaagccatgtcagccaaaccctttcta aaaaaagTGTattataaaaatcatatTCTTATATAATACTTGTGTcaatataatttat a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 417759..417777 /Source="Nicolas_upshift_promotors" /id="U280" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.257742257742258" /psig="0.581418581418581" /xcortree=1444 /SigmaFactorBS="ctttcgttatcaatcgaagccatgtcagccaaaccctttcta aaaaaagTGTattataaaaatcatatTCTTATATAATACTTGTGTcaatataatttat a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(417761) /Source="Nicolas_upshifts" /id="U281" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.936063936063936" /psig="0.97002997002997" /xcortree=1442 /SigmaFactorBS="tttttccaatatggaactatttgaaatgagtataaattaTAT TGACAcaagtattatataaGAATATGATTTTTATAATACactttttttagaaagggtt t" /listShort="dtpT" /GFF_Attribute="listLong" S_feature complement(417763..418267) /Source="Nicolas_S_feature" /locus_tag="new_417763_418267_c" /HighExp="S3, S4, LoTm, S5, S6, T5.0H, T4.0H, M9-stat, S8, T3.30H" /AntisenseName="yclG" /AntisenseCor="0.33937447534762299" /AntisenseRegPval="-7.9" /CDS_PredictionProba="NA" /TUshortSig="SigEF" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S128" promotor_-35 complement(417775..417782) /Source="Nicolas_upshift_promotors" /id="U281" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.936063936063936" /psig="0.97002997002997" /xcortree=1442 /SigmaFactorBS="tttttccaatatggaactatttgaaatgagtataaattaTAT TGACAcaagtattatataaGAATATGATTTTTATAATACactttttttagaaagggtt t" /listShort="dtpT" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 417931..417940 /Source="Nicolas_upshift_promotors" /id="U282" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=1425 /SigmaFactorBS="attcctttatatttttttaataaaattttagagaaatGTACA AGCAGatcgggcctttgTGAGTAACATGATAGTAATCatagagaaggaggctcgcaat t" /listShort="yclG" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 417953..417972 /Source="Nicolas_upshift_promotors" /id="U282" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=1425 /SigmaFactorBS="attcctttatatttttttaataaaattttagagaaatGTACA AGCAGatcgggcctttgTGAGTAACATGATAGTAATCatagagaaggaggctcgcaat t" /listShort="yclG" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 417954 /Source="Nicolas_upshifts" /id="U282" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=1425 /SigmaFactorBS="attcctttatatttttttaataaaattttagagaaatGTACA AGCAGatcgggcctttgTGAGTAACATGATAGTAATCatagagaaggaggctcgcaat t" /listShort="yclG" /GFF_Attribute="listLong" CDS 417993..419747 /gene="yclG" /locus_tag="BSU_03680" /old_locus_tag="BSU03680" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative uronase" /protein_id="NP_388250.1" /db_xref="EnsemblGenomes-Gn:BSU03680" /db_xref="EnsemblGenomes-Tr:CAB12176" /db_xref="InterPro:IPR006626" /db_xref="InterPro:IPR006633" /db_xref="InterPro:IPR011050" /db_xref="InterPro:IPR012334" /db_xref="InterPro:IPR024535" /db_xref="SubtiList:BG12028" /db_xref="UniProtKB/Swiss-Prot:P94409" /translation="MAEFILNAADFGVPRDGKTDSTERINQCLSTAVSKGYHTVWFPK GTYLIDATLGGDLNQRFRNAGIIVPGNLEIMMDPECIMKVIPNSSWGYSAFYVGKQEN ITISGGQIIGERDEHTYASAGIRSTHEWGFGICIEGCSNVVIDDVKISDFTGDGIIVS PRGLKTNQDYRTSEQIIIRRCEVRRSRRNNISITGCDMVTVEECLIEDAGTGNGTAPK FGIDIEGYGEGDVDYEEPINVSIRNNHFVGNVSSSVTNFNGYGILIEGNHSDNTISYG YGTQTVIKGNILRRPEDAAAAPRVGITGLGVSQGKETSDAVIAGNLITGFSTGIDVRG KSVLVTNNKISNFENTGILVYQSSDVKVDGNQIQNGLSETRRSIGLRAVLSDDIAFLN NCLIQVVDGVNVSGGNMIIKDNLLRKFSRGIWIAQGNAVIEGNTLNPDAFEAVPESYS VSVTNNAGAIIKNNTFKEFKNYPIYCSTSAKTSIIGNHLERSPLLVTIYISAGVHEIF DNTISVNRTAGNPIVIYLNGSAGSIISGNTINNLSAGTATAIQTNTSTNSKIIGNRIF KGTINKHSSDTIDGNMIV*" gene 417993..419747 /gene="yclG" /locus_tag="BSU_03680" /old_locus_tag="BSU03680" promotor_-10 complement(418264..418282) /Source="Nicolas_upshift_promotors" /id="U283" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1003 /SigmaFactorBS="atcccgttcgccgataatttgtcctccggaaataGTTATAtt ctcttgcttgcctACATAAAATGCGGAATAACcccacgaactattcggtatcactttc a" /listShort="S128, dtpT" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(418277) /Source="Nicolas_upshifts" /id="U283" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1003 /SigmaFactorBS="atcccgttcgccgataatttgtcctccggaaataGTTATAtt ctcttgcttgcctACATAAAATGCGGAATAACcccacgaactattcggtatcactttc a" /listShort="S128, dtpT" /GFF_Attribute="listLong" promotor_-35 complement(418298..418303) /Source="Nicolas_upshift_promotors" /id="U283" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1003 /SigmaFactorBS="atcccgttcgccgataatttgtcctccggaaataGTTATAtt ctcttgcttgcctACATAAAATGCGGAATAACcccacgaactattcggtatcactttc a" /listShort="S128, dtpT" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 419738 /Source="Nicolas_upshifts" /id="D160" /incds=0 /nref=6 /ntot=21 /MaxReadThrough="0.325519999999999" /MaxDrop="4.9689" /score="4.29139266" /energy="-5.4" /TU="NA" /idTUdmin="U282" /TUdmin=7 /isTUend="TRUE" CDS complement(419763..419984) /gene="yczF" /locus_tag="BSU_03690" /old_locus_tag="BSU03690" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_388251.1" /db_xref="EnsemblGenomes-Gn:BSU03690" /db_xref="EnsemblGenomes-Tr:CAB12177" /db_xref="GOA:O31479" /db_xref="SubtiList:BG12780" /db_xref="UniProtKB/Swiss-Prot:O31479" /translation="MKILGVTGFILICLLAISVLMDMLQGFSLTKAVYNNMSSFKMTT FAEWVVLLFFVLVLVREMYVIYKSKKKNP*" gene complement(419763..419984) /gene="yczF" /locus_tag="BSU_03690" /old_locus_tag="BSU03690" promotor_-10 complement(420003..420014) /Source="Nicolas_upshift_promotors" /id="U284" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=857 /SigmaFactorBS="aaattgagattatgcattagggttagatgcGGTATAActtct ccgccaaagATAGACACTAAAagcggaggatgatgaagcatgaagatattgggcgtga c" /listShort="yczF" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(420005) /Source="Nicolas_upshifts" /id="U284" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=857 /SigmaFactorBS="aaattgagattatgcattagggttagatgcGGTATAActtct ccgccaaagATAGACACTAAAagcggaggatgatgaagcatgaagatattgggcgtga c" /listShort="yczF" /GFF_Attribute="listLong" promotor_-35 complement(420029..420035) /Source="Nicolas_upshift_promotors" /id="U284" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=857 /SigmaFactorBS="aaattgagattatgcattagggttagatgcGGTATAActtct ccgccaaagATAGACACTAAAagcggaggatgatgaagcatgaagatattgggcgtga c" /listShort="yczF" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 420050..420056 /Source="Nicolas_upshift_promotors" /id="U285" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=903 /SigmaFactorBS="gagaagttataccgcatctaaccctaaTGCATAAtctcaatt ttaaaAGGAAGAATATGagaaaacgacaaggaaaggtatttgtgtatgcctttatttt c" /listShort="gerKA, gerKC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 420070..420081 /Source="Nicolas_upshift_promotors" /id="U285" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=903 /SigmaFactorBS="gagaagttataccgcatctaaccctaaTGCATAAtctcaatt ttaaaAGGAAGAATATGagaaaacgacaaggaaaggtatttgtgtatgcctttatttt c" /listShort="gerKA, gerKC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 420083 /Source="Nicolas_upshifts" /id="U285" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=903 /SigmaFactorBS="gagaagttataccgcatctaaccctaaTGCATAAtctcaatt ttaaaAGGAAGAATATGagaaaacgacaaggaaaggtatttgtgtatgcctttatttt c" /listShort="gerKA, gerKC" /GFF_Attribute="listLong" CDS 420110..421744 /gene="gerKA" /locus_tag="BSU_03700" /old_locus_tag="BSU03700" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:10762253, 16707705, 16740944" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10762253, 16707705, 16740944; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="spore germination receptor subunit" /protein_id="NP_388252.1" /db_xref="EnsemblGenomes-Gn:BSU03700" /db_xref="EnsemblGenomes-Tr:CAB12178" /db_xref="GOA:P49939" /db_xref="InterPro:IPR004995" /db_xref="SubtiList:BG11392" /db_xref="UniProtKB/Swiss-Prot:P49939" /translation="MPLFSKRKNNTDSKDKQNTDERNQEQQQEKERPVLISPSLAKNI AETKKEVGSSSDVIIREIKIGEQDHVHLAVIYISGLVDNNTIHESLIDPLVQDESIQN THAIQQILEKTLPLGGVKAEKSWDKLFSELMLGNALIFADGHDEALICSTQGGEQRSI QEPSTQVSFRGPRQGFTESLQTNISMIRRYIKNPNLWVEKMKKGSVTNTDIALMYIQG ICDEKVLKEVKQRLEKIDIDSILESGYIEQLIEDETFTTFPTMYHTERPDVVAGNLLE GRFAIIVDGTPFVLIAPALFVQFFQSVEDYYSRFDIATSIRILRVLVFFISLVAPAVY VAATTFHQEMIPTQLLVVIAAQREIVPFPAVVEALTMEVAFEILREAGVRLPRVVGSA VSIVGALVIGQAAVQAGIVSPAMVIIVALTAIASFATPAFAMAISARLIRFIFIIASA VMGFYGLILGIIMMFVHLCSLRSFGVPYMSPLAPFSSQGVKDALFRVPWWADEKRPES VSKEDKVRQGKDQRPEPAASRGMVNKDLEEGDQNGT*" gene 420110..421744 /gene="gerKA" /locus_tag="BSU_03700" /old_locus_tag="BSU03700" CDS 421734..422957 /gene="gerKC" /locus_tag="BSU_03710" /old_locus_tag="BSU03710" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:10762253, 16707705, 16740944, 19363077" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10762253, 16707705, 16740944, 19363077; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="spore germination receptor subunit" /protein_id="NP_388253.1" /db_xref="EnsemblGenomes-Gn:BSU03710" /db_xref="EnsemblGenomes-Tr:CAB12179" /db_xref="GOA:P49941" /db_xref="InterPro:IPR008844" /db_xref="SubtiList:BG11394" /db_xref="UniProtKB/Swiss-Prot:P49941" /translation="MVRKCLLAVLMLLSVIVLPGCWDKRELTDLAIISAIGIDRTNDS NYVLHLQIINPGNVAGGLQGGGAGDRPPVSVYSIEGNNITEALRKASMKVSRRLYFAH TNLVVINEKLAKEEGLDFVLDNLDRDTEFRTTATFVVAHKTKAENIVKILTPIDKIPS NKVNKTLDFTEAQYGRVVKINIQDVLKTLAANTMAPVIPGYMMIGDDKKGVSMENTQA TDPKAILQADGLAVFDKAGYLKYWLEDDESVGAVWLMNKIQHTFINADWGKTKDAVSL QVTHQDTKLVPKMRNGRPYIHVKVSVEGIIDAVKYPFQLSDPKVLAAIEKALNKELEK EISHTVKKIKKNKIDFIGFGDTIYRKYPEQWEKMKDTWDKEYLPELPIDVKAETYIRR TGLRNNPIKHQFKDD*" gene 421734..422957 /gene="gerKC" /locus_tag="BSU_03710" /old_locus_tag="BSU03710" CDS 422982..424103 /gene="gerKB" /locus_tag="BSU_03720" /old_locus_tag="BSU03720" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:10762253, 15849754, 16707705, 16740944, 16850406, 19363077" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10762253, 15849754, 16707705, 16740944, 16850406, 19363077; Product type cp : cell process" /codon_start=1 /transl_table=11 /product="spore germination receptor subunit" /protein_id="NP_388254.1" /db_xref="EnsemblGenomes-Gn:BSU03720" /db_xref="EnsemblGenomes-Tr:CAB12180" /db_xref="GOA:P49940" /db_xref="InterPro:IPR004761" /db_xref="SubtiList:BG11393" /db_xref="UniProtKB/Swiss-Prot:P49940" /translation="MEKARISIRQLFVMIIIFELGSSLLITPGSMAGRDAWIAVLLGC AIGLFLFYLYQGIYQCYPNSSPKEYMDDMLGTKLSWLFSFLYILYFAYIAARVLRDFG EMLLTFAYHDTPIIIVNALLMVVSIYAVRKGIEVLARAAELLFGAMYLLGAIGLVLII VSGTIDPHNLKPVLANGISPVLHSVFTQTMYVPFGEVVLFVMIFPNLNDRKDVKKMGM IAMAISGLIVALTVAINISVLDVDLTLRSQFPLLSTIQTIKVEEFLDRLDVFFMLALI IGGFFKVSLYLYATVVGTSTLFKEKNPSQLAYPMGLGILILSITIATNFSEHLNEGLN VVPLYIHLPFQLLFPLFLFIVAVWKKKRREKSKGEEAKK*" gene 422982..424103 /gene="gerKB" /locus_tag="BSU_03720" /old_locus_tag="BSU03720" downshifts 424087 /Source="Nicolas_upshifts" /id="D161" /incds=0 /nref=6 /ntot=58 /MaxReadThrough="2.55658" /MaxDrop="3.73002" /score="3.39927899" /energy="-10.5" /TU="NA" /idTUdmin="U285" /TUdmin=2200 /isTUend="FALSE" CDS complement(424208..424888) /gene="yclH" /locus_tag="BSU_03730" /old_locus_tag="BSU03730" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative ABC transporter (ATPase component)" /protein_id="NP_388255.1" /db_xref="EnsemblGenomes-Gn:BSU03730" /db_xref="EnsemblGenomes-Tr:CAB12181" /db_xref="GOA:P94411" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG12029" /db_xref="UniProtKB/Swiss-Prot:P94411" /translation="MSLLQFQQVGYWYKNKSQPLFQDINISFQKGKFYTIVGTSGTGK TTFLSLAGGLDAPKEGNILYDGKAVSKIGLTNFRNQYVSIVFQAYNLLPYMTALQNVT TAMEITGSKEKNKESYALDMLQKVGINEKQARQKVLTLSGGQQQRVSITRAFCCDTDL IVADEPTGNLDEDTSKEIVRLFQDLAHKEDKCVIMVTHDEQIAKVSDINIRLSRGSFT VKENVAVV*" gene complement(424208..424888) /gene="yclH" /locus_tag="BSU_03730" /old_locus_tag="BSU03730" CDS complement(424904..426364) /gene="yclI" /locus_tag="BSU_03740" /old_locus_tag="BSU03740" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative transporter" /protein_id="NP_388256.2" /db_xref="EnsemblGenomes-Gn:BSU03740" /db_xref="EnsemblGenomes-Tr:CAB12182" /db_xref="GOA:P94412" /db_xref="InterPro:IPR003838" /db_xref="InterPro:IPR025857" /db_xref="SubtiList:BG12030" /db_xref="UniProtKB/Swiss-Prot:P94412" /translation="MNFIKRAFWNMKAKKGKTLLQLFVFTVICVFVLSGLAIQSAAQK SSELARQELGGSVTLQVDRQKQMEKQQDSGEKRSFESTPIKVSDANKLAALDHVKSYN YTTSASANAGNFDAIESSSSSDSSSSSSSSNAKNSQGGGQGGPQMVQADLSIEGVIST ALVDDFSDGDSKITDGRAITKSDVGKKVTVINETLAEENDLSVGDSITIESATDEDTT VKLKIVGIYKTTSSGDDQAQNFSFLNPYNKLYTPYTATAALKGDDYKNTIDSAVYYMD DAKNMDTFVKAAKKTSIDFDTYTLNTNDQLYQQMVGPIENVASFSKNVVYLVSVAGAV ILGLIVMMSIRERKYEMGVLMAIGEKRWKLIGQFLTEILIVAVIAIGLASVTGNLVAN QLGNQLLSQQISSSTDSTQTASGQMPGGGGGMGGKMFGHSSSNVDVIDSLNVAVSMND MLILGGIGILIAIIATLLPSISVLRLHPKTILTKQE*" gene complement(424904..426364) /gene="yclI" /locus_tag="BSU_03740" /old_locus_tag="BSU03740" misc_feature 426534..426553 /Source="Nicolas_upshift_promotors" /id="U286" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.647352647352647" /psig="0.962037962037962" /xcortree=1584 /SigmaFactorBS="tctagttgatgaaataaaaactaacaattgtgaaacgcaaaa ccttctgtttaaaatGGTGCTATTATATAAAAAAGcatcaaaacaaccggaggatata a" /listShort="yclJ, yclK, S129, rapC, phrC" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 426537 /Source="Nicolas_upshifts" /id="U286" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.647352647352647" /psig="0.962037962037962" /xcortree=1584 /SigmaFactorBS="tctagttgatgaaataaaaactaacaattgtgaaacgcaaaa ccttctgtttaaaatGGTGCTATTATATAAAAAAGcatcaaaacaaccggaggatata a" /listShort="yclJ, yclK, S129, rapC, phrC" /GFF_Attribute="listLong" CDS 426577..427260 /gene="yclJ" /locus_tag="BSU_03750" /old_locus_tag="BSU03750" /function="16.10: Respire" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:11717295, 15375128, 20512483" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11717295, 15375128, 20512483; Product type r: regulator" /codon_start=1 /transl_table=11 /product="two-component response regulator [YclK] (possibly involved in arabinogalactan metabolism)" /protein_id="NP_388257.1" /db_xref="EnsemblGenomes-Gn:BSU03750" /db_xref="EnsemblGenomes-Tr:CAB12183" /db_xref="GOA:P94413" /db_xref="InterPro:IPR001789" /db_xref="InterPro:IPR001867" /db_xref="InterPro:IPR011006" /db_xref="InterPro:IPR016032" /db_xref="InterPro:IPR036388" /db_xref="SubtiList:BG12031" /db_xref="UniProtKB/Swiss-Prot:P94413" /translation="MKILMIEDNVSVCTMTEMFFFKEGFEAEFVHDGLEGYQRFTEEN WDLIILDIMLPSMDGVTICRKIRETSTVPIIMLTAKDTESDQVIGFEMGADDYVTKPF SPLTLVARIKAVIRRYKATGKAVIDEDMIETECFTINKKTREVLLNGEPVENLTPKEF DLLYYLVQNPRQVFSREQLLEQVWGYQFYGDERTVDVHIKRLRKKLASEDKPFLYTVW GVGYKFDED*" gene 426577..427260 /gene="yclJ" /locus_tag="BSU_03750" /old_locus_tag="BSU03750" CDS 427247..428668 /gene="yclK" /locus_tag="BSU_03760" /old_locus_tag="BSU03760" /function="16.3: Control" /function="16.10: Respire" /function="16.12: Sense" /experiment="publication(s) with functional evidences, PMID:11717295, 15375128, 20512483" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11717295, 15375128, 20512483; Product type rc: receptor" /codon_start=1 /transl_table=11 /product="two-component sensor histidine kinase [YclJ]" /protein_id="NP_388258.1" /db_xref="EnsemblGenomes-Gn:BSU03760" /db_xref="EnsemblGenomes-Tr:CAB12184" /db_xref="GOA:P94414" /db_xref="InterPro:IPR003594" /db_xref="InterPro:IPR003660" /db_xref="InterPro:IPR003661" /db_xref="InterPro:IPR004358" /db_xref="InterPro:IPR005467" /db_xref="InterPro:IPR036097" /db_xref="InterPro:IPR036890" /db_xref="SubtiList:BG12032" /db_xref="UniProtKB/Swiss-Prot:P94414" /translation="MMKIKYLYQLLLSHISILILAFVIIISLFSHFVKEFAYQNKVEE LTSYAVQIANEFQSGQVDMRRLYPYQDILSTRKTQFIIFNEEQQPYFLPEGFHHPPRE QLKKSEWNKLKKGQTVTIRADGRFDDEVSLVAQPIFVQNEFKGAVLLISPISGVEQMV NQVNLYMFYAVISTLVITILVSWLLSKFHVKRIQKLREATDKVASGDYDIHLENSYGD EIGVLASDFNIMAKKLKQSRDEIERLEKRRRQFIADVSHELKTPLTTINGLVEGLNSH TIPEDKKDKCFSLISEETKRMLRLVKENLDYEKIRSQQITLNKLDVPLIEVFEIVKEH LQQQAEEKQNKLMIQVEDHVIVHADYDRFIQILVNITKNSIQFTQNGDIWLRGMEGYK ETIIEIEDTGIGIPKEDIEHIWERFYKADISRTNTAYGEYGLGLSIVRQLVEMHQGTV EIKSEEGKGTKFIIRLPLTAKQQ*" gene 427247..428668 /gene="yclK" /locus_tag="BSU_03760" /old_locus_tag="BSU03760" downshifts 428644 /Source="Nicolas_upshifts" /id="D162" /incds=0 /nref=20 /ntot=169 /MaxReadThrough="3.43905" /MaxDrop="4.91565" /score="13.4599201" /energy="-15" /TU="U286" /idTUdmin="U286" /TUdmin="-1427" /isTUend="FALSE" S_feature 428689..428793 /Source="Nicolas_S_feature" /locus_tag="new_428689_428793" /HighExp="Lbstat, nit, ferm, BI, M0t45, M40t45, M0t90, S0, S2, Paraq" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.962" /TUlongSig="NA" /TUlongPSig="NA" /label="S129" misc_feature 428783..428802 /Source="Nicolas_upshift_promotors" /id="U287" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.96903096903097" /psig="0.986013986013986" /xcortree=678 /SigmaFactorBS="tcccgaaaacaaagattgcgtgtttttcgggttgggacggcc tataaaCATGATAAAATATGACATAAacagtttttgatgggagagggtgaaggaatga a" /listShort="rapC, phrC" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 428795 /Source="Nicolas_upshifts" /id="U287" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.96903096903097" /psig="0.986013986013986" /xcortree=678 /SigmaFactorBS="tcccgaaaacaaagattgcgtgtttttcgggttgggacggcc tataaaCATGATAAAATATGACATAAacagtttttgatgggagagggtgaaggaatga a" /listShort="rapC, phrC" /GFF_Attribute="listLong" downshifts complement(428827) /Source="Nicolas_upshifts" /id="D163" /incds=0 /nref=2 /ntot=81 /MaxReadThrough="1.74985" /MaxDrop="4.10695" /score="1.47729412" /energy="-10.3" /TU="NA" /idTUdmin="U290" /TUdmin=1320 /isTUend="FALSE" CDS 428831..429979 /gene="rapC" /locus_tag="BSU_03770" /old_locus_tag="BSU03770" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:10464187, 12456319, 12897006, 12950917, 15968044, 19202088" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10464187, 12456319, 12897006, 12950917, 15968044, 19202088; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="response regulator aspartate phosphatase" /protein_id="NP_388259.1" /db_xref="EnsemblGenomes-Gn:BSU03770" /db_xref="EnsemblGenomes-Tr:CAB12185" /db_xref="GOA:P94415" /db_xref="InterPro:IPR011990" /db_xref="InterPro:IPR013026" /db_xref="InterPro:IPR019734" /db_xref="SubtiList:BG11966" /db_xref="UniProtKB/Swiss-Prot:P94415" /translation="MKSGVIPSSAVGQKINEWYRYIRTFSVPDAEVLKAEIQQELKHM QHDSNLLLYYSLMEFRHQLMLDYLEPLEKLNIEDQPSLSELSRNIDSNQADLKGLLDY YVNFFRGMYEFDKREFISAITYYKQAEKKLSFVADHIERAEFYFKIAEAYYYMKQTYF SLINIKNAYEIYVEQETYNVRIIQCHFVFGVNLMDERNFEQAARHFKLALNMAQAEQK AQLVGRAYYNLGLCYYNQDLLDPAIDYFEKAVSTFESSRIVNSLPQAYFLITLIYYKQ GKHDKASEYHKRGYEYAKETDDADYAVKFEFLQSLYLDQPNEEGIERCFQYLKNKNMY ADIEDLALEVAKYYYEQKWFKLSASYFLQVEEARKQIQRSEGLYEIEI*" gene 428831..429979 /gene="rapC" /locus_tag="BSU_03770" /old_locus_tag="BSU03770" promotor_-35 429679..429684 /Source="Nicolas_upshift_promotors" /id="U288" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.776223776223776" /psig="0.776223776223776" /xcortree=1063 /SigmaFactorBS="caccctgatttattataaacagggaaaacatgataaagcttc GGAATAtcacaagcggggctatGAATATGCTAAAGAAACAGacgatgcagactatgcc g" /listShort="phrC" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 429697 /Source="Nicolas_upshifts" /id="U288" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.776223776223776" /psig="0.776223776223776" /xcortree=1063 /SigmaFactorBS="caccctgatttattataaacagggaaaacatgataaagcttc GGAATAtcacaagcggggctatGAATATGCTAAAGAAACAGacgatgcagactatgcc g" /listShort="phrC" /GFF_Attribute="listLong" promotor_-10 429701..429719 /Source="Nicolas_upshift_promotors" /id="U288" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.776223776223776" /psig="0.776223776223776" /xcortree=1063 /SigmaFactorBS="caccctgatttattataaacagggaaaacatgataaagcttc GGAATAtcacaagcggggctatGAATATGCTAAAGAAACAGacgatgcagactatgcc g" /listShort="phrC" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 429841..429849 /Source="Nicolas_upshift_promotors" /id="U289" /multdbtbs="SigH" /comp="M1" /sig="SigH" /pcomp="0.753246753246753" /psig="0.753246753246753" /xcortree=788 /SigmaFactorBS="taaaaaataaaaatatgtacgctgatatAGAGGATTTagccc tagaagTAGCAAAATATTACTATGAacagaaatggtttaaactgtctgcttcctactt t" /listShort="phrC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 429861..429879 /Source="Nicolas_upshift_promotors" /id="U289" /multdbtbs="SigH" /comp="M1" /sig="SigH" /pcomp="0.753246753246753" /psig="0.753246753246753" /xcortree=788 /SigmaFactorBS="taaaaaataaaaatatgtacgctgatatAGAGGATTTagccc tagaagTAGCAAAATATTACTATGAacagaaatggtttaaactgtctgcttcctactt t" /listShort="phrC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 429873 /Source="Nicolas_upshifts" /id="U289" /multdbtbs="SigH" /comp="M1" /sig="SigH" /pcomp="0.753246753246753" /psig="0.753246753246753" /xcortree=788 /SigmaFactorBS="taaaaaataaaaatatgtacgctgatatAGAGGATTTagccc tagaagTAGCAAAATATTACTATGAacagaaatggtttaaactgtctgcttcctactt t" /listShort="phrC" /GFF_Attribute="listLong" CDS 429963..430085 /gene="phrC" /locus_tag="BSU_03780" /old_locus_tag="BSU03780" /function="16.3: Control" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:10464187, 12456319, 12897006, 12950917, 16816200, 19202088" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10464187, 12456319, 12897006, 12950917, 16816200, 19202088; Product type r : regulator" /codon_start=1 /transl_table=11 /product="secreted regulator of the activity of phosphatase RapC and competence and sporulation stimulating factor (CSF)" /protein_id="NP_388260.1" /db_xref="EnsemblGenomes-Gn:BSU03780" /db_xref="EnsemblGenomes-Tr:CAB12186" /db_xref="GOA:P94416" /db_xref="InterPro:IPR020243" /db_xref="InterPro:IPR025899" /db_xref="SubtiList:BG11959" /db_xref="UniProtKB/Swiss-Prot:P94416" /translation="MKLKSKLFVICLAAAAIFTAAGVSANAEALDFHVTERGMT*" gene 429963..430085 /gene="phrC" /locus_tag="BSU_03780" /old_locus_tag="BSU03780" downshifts 430072 /Source="Nicolas_upshifts" /id="D164" /incds=0 /nref=260 /ntot=275 /MaxReadThrough="3.24518" /MaxDrop="7.70367" /score="26.3182765" /energy="-14" /TU="NA" /idTUdmin="U286" /TUdmin=1 /isTUend="TRUE" downshifts complement(430140) /Source="Nicolas_upshifts" /id="D165" /incds=0 /nref=3 /ntot=64 /MaxReadThrough="0.60499" /MaxDrop="7.4475" /score="-1.25354129" /energy="-15.8" /TU="NA" /idTUdmin="U290" /TUdmin=7 /isTUend="TRUE" CDS complement(430185..430274) /gene="yczM" /locus_tag="BSU_03788" /old_locus_tag="BSU03788" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 20156992, 21670523; Product type f: factor" /codon_start=1 /transl_table=11 /product="putative type I toxin" /protein_id="YP_003097676.1" /db_xref="EnsemblGenomes-Gn:BSU03788" /db_xref="EnsemblGenomes-Tr:CAX52547" /db_xref="GOA:C0H3V0" /db_xref="InterPro:IPR010070" /db_xref="UniProtKB/Swiss-Prot:C0H3V0" /translation="MSGYGTSFALIVVLFILLIIVGTAFVGGY*" gene complement(430185..430274) /gene="yczM" /locus_tag="BSU_03788" /old_locus_tag="BSU03788" downshifts complement(430345) /Source="Nicolas_upshifts" /id="D166" /incds=0 /nref=25 /ntot=113 /MaxReadThrough="7.05273" /MaxDrop="3.3619" /score="32.1465401" /energy="-16.5" /TU="U290" /idTUdmin="U290" /TUdmin="-198" /isTUend="FALSE" CDS complement(430356..430469) /gene="yczN" /locus_tag="BSU_03789" /old_locus_tag="BSU03789" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 21670523; Product type f: factor" /codon_start=1 /transl_table=11 /product="putative spore and germination protein" /protein_id="YP_003097677.1" /db_xref="EnsemblGenomes-Gn:BSU03789" /db_xref="EnsemblGenomes-Tr:CAX52548" /db_xref="GOA:C0H3V1" /db_xref="InterPro:IPR010070" /db_xref="UniProtKB/Swiss-Prot:C0H3V1" /translation="MSGYSNGGGYGGISSFALIVVLFILLIIVGTAFVGGF*" gene complement(430356..430469) /gene="yczN" /locus_tag="BSU_03789" /old_locus_tag="BSU03789" promotor_-10 complement(430490..430509) /Source="Nicolas_upshift_promotors" /id="U290" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1406 /SigmaFactorBS="attcttcattttttctcttgtccactattaTCCCTGCCAAat ggatcggttcAGCATATCTTATAGTATCCTtcatagggaggtgaaaccttatgtcagg a" /listShort="yczN, yczM" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(430501) /Source="Nicolas_upshifts" /id="U290" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1406 /SigmaFactorBS="attcttcattttttctcttgtccactattaTCCCTGCCAAat ggatcggttcAGCATATCTTATAGTATCCTtcatagggaggtgaaaccttatgtcagg a" /listShort="yczN, yczM" /GFF_Attribute="listLong" promotor_-35 complement(430522..430531) /Source="Nicolas_upshift_promotors" /id="U290" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1406 /SigmaFactorBS="attcttcattttttctcttgtccactattaTCCCTGCCAAat ggatcggttcAGCATATCTTATAGTATCCTtcatagggaggtgaaaccttatgtcagg a" /listShort="yczN, yczM" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(430623..431987) /gene="thrD" /locus_tag="BSU_03790" /old_locus_tag="BSU03790" /EC_number="2.7.2.4" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:2152900, 11471740, 27260660" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 2152900, 11471740, 27260660; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="aspartate kinase III" /protein_id="NP_388261.1" /db_xref="EnsemblGenomes-Gn:BSU03790" /db_xref="EnsemblGenomes-Tr:CAB12187" /db_xref="GOA:P94417" /db_xref="InterPro:IPR001048" /db_xref="InterPro:IPR001341" /db_xref="InterPro:IPR002912" /db_xref="InterPro:IPR005260" /db_xref="InterPro:IPR018042" /db_xref="InterPro:IPR027795" /db_xref="InterPro:IPR035804" /db_xref="InterPro:IPR036393" /db_xref="SubtiList:BG12033" /db_xref="UniProtKB/Swiss-Prot:P94417" /translation="MKVVKFGGSSLASGAQLDKVFHIVTSDPARKAVVVSAPGKHYAE DTKVTDLLIACAEQYLATGSAPELAEAVVERYALIANELQLGQSIIEKIRDDLFTLLE GDKSNPEQYLDAVKASGEDNNAKLIAAYFRYKGVKAEYVNPKDAGLFVTNEPGNAQVL PESYQNLYRLRERDGLIIFPGFFGFSKDGDVITFSRSGSDITGSILANGLQADLYENF TDVDAVYSVNPSFVENPKEISELTYREMRELSYAGFSVFHDEALIPAFRAGIPVQIKN TNNPSAEGTRVVSKRDNTNGPVVGIASDTGFCSIYISKYLMNREIGFGRRALQILEEH GLTYEHVPSGIDDMTIILRQGQMDAATERSVIKRIEEDLHADEVIVEHHLALIMVVGE AMRHNVGTTARAAKALSEAQVNIEMINQGSSEVSMMFGVKEAEERKAVQALYQEFFAG VLIS*" gene complement(430623..431987) /gene="thrD" /locus_tag="BSU_03790" /old_locus_tag="BSU03790" downshifts complement(430631) /Source="Nicolas_upshifts" /id="D167" /incds=0 /nref=23 /ntot=129 /MaxReadThrough="2.21842" /MaxDrop="4.81019" /score="44.9085917" /energy="-15" /TU="NA" /idTUdmin="U291" /TUdmin=0 /isTUend="TRUE" downshifts complement(430675) /Source="Nicolas_upshifts" /id="D168" /incds=0 /nref=1 /ntot=17 /MaxReadThrough="5.53807" /MaxDrop="2.54279" /score="44.9085917" /energy="-15" /TU="U291" /idTUdmin="U291" /TUdmin="-44" /isTUend="FALSE" promotor_-10 complement(432023..432042) /Source="Nicolas_upshift_promotors" /id="U291" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.946053946053946" /psig="0.999000999001" /xcortree=3042 /SigmaFactorBS="aaaaatacaaatgttctcctgagaaagaaattcccCCTTGAT TtacagtactgaaagAGAGATAATAAATACTAAATttgtgtgaaaattttaaacatta g" /listShort="yclM" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(432039) /Source="Nicolas_upshifts" /id="U291" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.946053946053946" /psig="0.999000999001" /xcortree=3042 /SigmaFactorBS="aaaaatacaaatgttctcctgagaaagaaattcccCCTTGAT TtacagtactgaaagAGAGATAATAAATACTAAATttgtgtgaaaattttaaacatta g" /listShort="yclM" /GFF_Attribute="listLong" promotor_-35 complement(432057..432064) /Source="Nicolas_upshift_promotors" /id="U291" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.946053946053946" /psig="0.999000999001" /xcortree=3042 /SigmaFactorBS="aaaaatacaaatgttctcctgagaaagaaattcccCCTTGAT TtacagtactgaaagAGAGATAATAAATACTAAATttgtgtgaaaattttaaacatta g" /listShort="yclM" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 432178..432182 /Source="Nicolas_upshift_promotors" /id="U292" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.843156843156843" /psig="0.997002997002997" /xcortree=2746 /SigmaFactorBS="aaatatggtaaacagcctaacgttttggGATGGaaaatggtt agaatgATTAGTAAAATTGATAAATGactaggttaatatttttaaagaatattgacta a" /listShort="S130, yclN, yclO, yclP, yclQ" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 432198..432217 /Source="Nicolas_upshift_promotors" /id="U292" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.843156843156843" /psig="0.997002997002997" /xcortree=2746 /SigmaFactorBS="aaatatggtaaacagcctaacgttttggGATGGaaaatggtt agaatgATTAGTAAAATTGATAAATGactaggttaatatttttaaagaatattgacta a" /listShort="S130, yclN, yclO, yclP, yclQ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 432210 /Source="Nicolas_upshifts" /id="U292" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.843156843156843" /psig="0.997002997002997" /xcortree=2746 /SigmaFactorBS="aaatatggtaaacagcctaacgttttggGATGGaaaatggtt agaatgATTAGTAAAATTGATAAATGactaggttaatatttttaaagaatattgacta a" /listShort="S130, yclN, yclO, yclP, yclQ" /GFF_Attribute="listLong" promotor_-35 432241..432248 /Source="Nicolas_upshift_promotors" /id="U293" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.926073926073926" /psig=1 /xcortree=2099 /SigmaFactorBS="ataaatgactaggttaatatttttaaagaaTATTGACTaacc ctataaaaaTGGTAATATGTAAATGATAAtgataatcaattactatatggccatattg t" /listShort="S130, yclN, yclO, yclP, yclQ" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 432262..432281 /Source="Nicolas_upshift_promotors" /id="U293" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.926073926073926" /psig=1 /xcortree=2099 /SigmaFactorBS="ataaatgactaggttaatatttttaaagaaTATTGACTaacc ctataaaaaTGGTAATATGTAAATGATAAtgataatcaattactatatggccatattg t" /listShort="S130, yclN, yclO, yclP, yclQ" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 432271..432371 /Source="Nicolas_S_feature" /locus_tag="new_432271_432371" /HighExp="LBGexp, Lbexp, G150, dia0, G135, H2O2, Paraq, dia15, G180, Diami" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="1, 0.997" /TUlongSig="NA" /TUlongPSig="NA" /label="S130" upshifts 432271 /Source="Nicolas_upshifts" /id="U293" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.926073926073926" /psig=1 /xcortree=2099 /SigmaFactorBS="ataaatgactaggttaatatttttaaagaaTATTGACTaacc ctataaaaaTGGTAATATGTAAATGATAAtgataatcaattactatatggccatattg t" /listShort="S130, yclN, yclO, yclP, yclQ" /GFF_Attribute="listLong" CDS 432372..433322 /gene="pbtN" /locus_tag="BSU_03800" /old_locus_tag="BSU03800" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:12354229, 15849754, 16850406, 19955416" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12354229, 15849754, 16850406, 19955416; Product type t: transporter" /codon_start=1 /transl_table=11 /product="petrobactin iron-siderophore ABC transporter (permease)" /protein_id="NP_388262.1" /db_xref="EnsemblGenomes-Gn:BSU03800" /db_xref="EnsemblGenomes-Tr:CAB12188" /db_xref="GOA:P94418" /db_xref="InterPro:IPR000522" /db_xref="InterPro:IPR035568" /db_xref="SubtiList:BG12034" /db_xref="UniProtKB/Swiss-Prot:P94418" /translation="MKLRYLFILLIILAVTSVFIGVEDLSPLDLFDLSKQEASTLFAS RLPRLISIVIAGLSMSICGLIMQQISRNKFVSPTTAGTMDWARLGILISLLLFTSASP LIKMLVAFVFALAGNFLFMKILERIKFNDTIFIPLVGLMLGNIVSSIATFIAYKYDLI QNVSSWLQGDFSLVVKGRYELLYLSIPLVIIAYVYADKFTLAGMGESFSVNLGLKYKR VVNIGLIIVSLITSLVILTVGMLPFLGLIIPNIVSIYRGDNLKSSLPHTVLLGAVFVL FCDILGRIIIFPYEISIGLMVGIIGSGIFLFMLLRRKAYA*" gene 432372..433322 /gene="pbtN" /locus_tag="BSU_03800" /old_locus_tag="BSU03800" CDS 433315..434262 /gene="pbtO" /locus_tag="BSU_03810" /old_locus_tag="BSU03810" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:12354229, 15849754, 16850406, 19955416" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12354229, 15849754, 16850406, 19955416; Product type t: transporter" /codon_start=1 /transl_table=11 /product="petrobactin iron-siderophore ABC transporter (permease)" /protein_id="NP_388263.1" /db_xref="EnsemblGenomes-Gn:BSU03810" /db_xref="EnsemblGenomes-Tr:CAB12189" /db_xref="GOA:P94419" /db_xref="InterPro:IPR000522" /db_xref="InterPro:IPR035568" /db_xref="SubtiList:BG12035" /db_xref="UniProtKB/Swiss-Prot:P94419" /translation="MRNQMKIALLVGLAIVCIGLFLFYDLGNWDYTLPRRIKKVAAIV LTGGAIAFSTMIFQTITNNRILTPSILGLDSLYMLIQTGIIFLFGSANMVIMNKNINF IISVLLMILFSLVLYQIMFKGEGRNIFFLLLIGIVFGTLFSSLSSFMQMLIDPNEFQV VQDKMFASFNNINTDLLWLAFIIFLLTGVYVWRFTKFFDVLSLGREHAVNLGIDYDKV VKQMLIVVAILVSVSTALVGPIMFLGLLVVNLAREFLKTYKHSYLIAGSVFISIIALV GGQFVVEKVFTFSTTLSVIINFAGGIYFIYLLLKENKSW*" gene 433315..434262 /gene="pbtO" /locus_tag="BSU_03810" /old_locus_tag="BSU03810" CDS 434256..435014 /gene="pbtP" /locus_tag="BSU_03820" /old_locus_tag="BSU03820" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:12354229, 19955416" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12354229, 19955416; Product type t: transporter" /codon_start=1 /transl_table=11 /product="petrobactin iron-siderophore ABC transporter (ATP-binding protein)" /protein_id="NP_388264.1" /db_xref="EnsemblGenomes-Gn:BSU03820" /db_xref="EnsemblGenomes-Tr:CAB12190" /db_xref="GOA:P94420" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR017871" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG12036" /db_xref="UniProtKB/Swiss-Prot:P94420" /translation="MVEVRNVSKQYGGKVVLEETSVTIQKGKITSFIGPNGAGKSTLL SIMSRLIKKDSGEIYIDGQEIGACDSKELAKKMSILKQANQINIRLTIKDLVSFGRFP YSQGRLTEEDWVHINQALSYMKLEDIQDKYLDQLSGGQCQRAFIAMVIAQDTDYIFLD EPLNNLDMKHSVEIMKLLKRLVEELGKTIVIVIHDINFASVYSDYIVALKNGRIVKEG PPEEMIETSVLEEIYDMTIPIQTIDNQRIGVYFS*" gene 434256..435014 /gene="pbtP" /locus_tag="BSU_03820" /old_locus_tag="BSU03820" CDS 435036..435989 /gene="pbtQ" /locus_tag="BSU_03830" /old_locus_tag="BSU03830" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:12354229, 19955416, 25355936" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12354229, 19955416, 25355936; Product type t: transporter" /codon_start=1 /transl_table=11 /product="petrobactin iron-siderophore ABC transporter (binding lipoprotein)" /protein_id="NP_388265.1" /db_xref="EnsemblGenomes-Gn:BSU03830" /db_xref="EnsemblGenomes-Tr:CAB12191" /db_xref="GOA:P94421" /db_xref="InterPro:IPR002491" /db_xref="InterPro:IPR033870" /db_xref="PDB:3GFV" /db_xref="SubtiList:BG12037" /db_xref="UniProtKB/Swiss-Prot:P94421" /translation="MKKFALLFIALVTAVVISACGNQSTSSKGSDTKKEQITVKHQLD KNGTKVPKNPKKVVVFDFGSLDTLDKLGLDDIVAGLPKQVLPKYLSKFKDDKYADVGS LKEPDFDKVAELDPDLIIISARQSESYKEFSKIAPTIYLGVDTAKYMESFKSDAETIG KIFDKEDKVKDELANIDHSIADVKKTAEKLNKNGLVIMANDGKISAFGPKSRYGLIHD VFGVAPADQNIKASTHGQSVSYEYISKTNPDYLFVIDRGTAIGETSSTKQVVENDYVK NVNAVKNGHVIYLDSATWYLSGGGLESMTQMIKEVKDGLEK*" gene 435036..435989 /gene="pbtQ" /locus_tag="BSU_03830" /old_locus_tag="BSU03830" downshifts 435972 /Source="Nicolas_upshifts" /id="D169" /incds=0 /nref=161 /ntot=280 /MaxReadThrough="3.87669" /MaxDrop="7.4722" /score="31.9942335" /energy="-13.8" /TU="U293" /idTUdmin="U292" /TUdmin=5 /isTUend="TRUE" CDS complement(436036..437454) /gene="ycnB" /locus_tag="BSU_03840" /old_locus_tag="BSU03840" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 15855514, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative efflux transporter" /protein_id="NP_388266.1" /db_xref="EnsemblGenomes-Gn:BSU03840" /db_xref="EnsemblGenomes-Tr:CAB12192" /db_xref="GOA:P94422" /db_xref="InterPro:IPR004638" /db_xref="InterPro:IPR011701" /db_xref="InterPro:IPR020846" /db_xref="InterPro:IPR036259" /db_xref="SubtiList:BG12038" /db_xref="UniProtKB/Swiss-Prot:P94422" /translation="MNTSIEQKPFNRSVIVGILLAGAFVAILNQTLLITALPHIMRDF NVDANQAQWLTTSFMLTNGILIPITAFLIEKFTSRALLITAMSIFTAGTVVGAFAPNF PVLLTARIIQAAGAGIMMPLMQTVFLTIFPIEKRGQAMGMVGLVISFAPAIGPTLSGW AVEAFSWRSLFYIILPFAVIDLILASILMKNVTTLRKTQIDILSVILSTFGFGGLLYG FSSVGSYGWSSSTVLISLLVGVIALLLFITRQMKLKKPMLEFRVFTFGVFSLTTLLGT LVFALLIGTETILPLYTQNVRDVTAFDTGLMLLPGAVVMGFMSPIIGRIFDRVGGRGL AIAGFCIIFLTSLPFMQLTDHTSLAWIVVLYTVRLLGTAMIMMPVTTAGINALPRHLI PHGTAMNNTIRQVGGSIGTALLVSVMSNQAAHAGTTNVKHAALHGMNAAFIVAAVIAL VGFLLSFTLKKPQRPAEQQPAR*" gene complement(436036..437454) /gene="ycnB" /locus_tag="BSU_03840" /old_locus_tag="BSU03840" downshifts complement(436057) /Source="Nicolas_upshifts" /id="D170" /incds=0 /nref=8 /ntot=150 /MaxReadThrough="2.00954" /MaxDrop="5.13029" /score="17.5501827" /energy="-13.8" /TU="NA" /idTUdmin="U294" /TUdmin="-14" /isTUend="TRUE" CDS complement(437474..438352) /gene="ycnC" /locus_tag="BSU_03850" /old_locus_tag="BSU03850" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative transcriptional regulator (TetR/AcrR family)" /protein_id="NP_388267.2" /db_xref="EnsemblGenomes-Gn:BSU03850" /db_xref="EnsemblGenomes-Tr:CAB12193" /db_xref="GOA:P94423" /db_xref="InterPro:IPR001647" /db_xref="InterPro:IPR009057" /db_xref="SubtiList:BG12039" /db_xref="UniProtKB/Swiss-Prot:P94423" /translation="MLDKKTDILLAARKLFSEKDFTSVSMQAIAEECKMSKASIYKLF QSKEDLLLELLSFNQKQMVAAASRLQENTALTPEERLTQKVKMELEGFRRNQQFFNML TYGNPKLHNDRVKQHIHQTRSTIICWHRDSLIQAYGETILPFVWDLVIILHGMMREFL MLIKIEEKPLELDPIAEFIISTLNQIIKNRETRQSLLPPEAIELYIHSASSYKPKDKS VLLSESLKELHKGISSLSAADYDVDELTSAAAMLEEEAKKEEPRAFLLKSLIGYLEQT GVLTQPVSMLKTLLIT*" gene complement(437474..438352) /gene="ycnC" /locus_tag="BSU_03850" /old_locus_tag="BSU03850" S_feature complement(438353..438419) /Source="Nicolas_S_feature" /locus_tag="new_438353_438419_c" /HighExp="dia15, H2O2, Diami, Paraq, Oxctl, Cold, G180, Salt, BMM, GM 120" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S131" promotor_-10 complement(438418..438437) /Source="Nicolas_upshift_promotors" /id="U294" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.373626373626374" /psig="0.999000999001" /xcortree=2489 /SigmaFactorBS="gcaggcctttcatttacccggttaaaatcCATTGACttctat tttgtttaTCTGGTAAAATTTTTTCATTgttactcattggttttctgtgaaccaatgg g" /listShort="S131, ycnC, ycnB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(438427) /Source="Nicolas_upshifts" /id="U294" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.373626373626374" /psig="0.999000999001" /xcortree=2489 /SigmaFactorBS="gcaggcctttcatttacccggttaaaatcCATTGACttctat tttgtttaTCTGGTAAAATTTTTTCATTgttactcattggttttctgtgaaccaatgg g" /listShort="S131, ycnC, ycnB" /GFF_Attribute="listLong" promotor_-35 complement(438452..438458) /Source="Nicolas_upshift_promotors" /id="U294" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.373626373626374" /psig="0.999000999001" /xcortree=2489 /SigmaFactorBS="gcaggcctttcatttacccggttaaaatcCATTGACttctat tttgtttaTCTGGTAAAATTTTTTCATTgttactcattggttttctgtgaaccaatgg g" /listShort="S131, ycnC, ycnB" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(438516..439265) /gene="nfrAB" /locus_tag="BSU_03860" /old_locus_tag="BSU03860" /EC_number="1.5.1.39" /EC_number="1.6.99.-" /function="16.11: Scavenge (Catabolism)" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:16229462, 9836433, 20862523" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16229462, 9836433, 20862523; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="NADPH-FMN oxidoreductase (nitroreductase)" /protein_id="NP_388268.1" /db_xref="EnsemblGenomes-Gn:BSU03860" /db_xref="EnsemblGenomes-Tr:CAB12194" /db_xref="GOA:P94424" /db_xref="InterPro:IPR000415" /db_xref="InterPro:IPR016446" /db_xref="InterPro:IPR029479" /db_xref="PDB:1ZCH" /db_xref="SubtiList:BG12040" /db_xref="UniProtKB/Swiss-Prot:P94424" /translation="MNEVIKSLTDHRSIRSYTDEPVAQEQLDQIIEAVQSAPSSINGQ QVTVITVQDKERKKKISELAGGQPWIDQAPVFLLFCADFNRAKIALEDLHDFKMEITN GLESVLVGAVDAGIALGTATAAAESLGLGTVPIGAVRGNPQELIELLELPKYVFPLSG LVIGHPADRSAKKPRLPQEAVNHQETYLNQDELTSHIQAYDEQMSEYMNKRTNGKETR NWSQSIASYYERLYYPHIREMLEKQGFKVEK*" gene complement(438516..439265) /gene="nfrAB" /locus_tag="BSU_03860" /old_locus_tag="BSU03860" downshifts complement(438529) /Source="Nicolas_upshifts" /id="D171" /incds=0 /nref=136 /ntot=243 /MaxReadThrough="2.08639" /MaxDrop="5.10745" /score="11.1864402" /energy="-18.6" /TU="NA" /idTUdmin="U296" /TUdmin=0 /isTUend="TRUE" CDS complement(439282..439569) /gene="ycnE" /locus_tag="BSU_03870" /old_locus_tag="BSU03870" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 17274596, 21454635; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative AI-2 degrading enzyme" /protein_id="NP_388269.1" /db_xref="EnsemblGenomes-Gn:BSU03870" /db_xref="EnsemblGenomes-Tr:CAB12195" /db_xref="GOA:P94425" /db_xref="InterPro:IPR007138" /db_xref="InterPro:IPR011008" /db_xref="SubtiList:BG12041" /db_xref="UniProtKB/Swiss-Prot:P94425" /translation="MIVLQAYIKVKPEKREEFLSEAQSLVQHSRAEEGNAQYDLFEKV GEENTFVMLEKWKDEAAMKFHNETAHFQGFVAKGKELLSAPLDVVRTELSE*" gene complement(439282..439569) /gene="ycnE" /locus_tag="BSU_03870" /old_locus_tag="BSU03870" promotor_-35 439535..439542 /Source="Nicolas_upshift_promotors" /id="U295" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.966033966033966" /psig="0.993006993006993" /xcortree=1982 /SigmaFactorBS="aaaattcctcgcgtttttctGGTTTTACtttgatgtaagctT GTAATACGATCATGTAAATctcctccgtcgttatgcgaatttattgttcgaatttcat c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 439556..439575 /Source="Nicolas_upshift_promotors" /id="U295" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.966033966033966" /psig="0.993006993006993" /xcortree=1982 /SigmaFactorBS="aaaattcctcgcgtttttctGGTTTTACtttgatgtaagctT GTAATACGATCATGTAAATctcctccgtcgttatgcgaatttattgttcgaatttcat c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 439575 /Source="Nicolas_upshifts" /id="U295" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.966033966033966" /psig="0.993006993006993" /xcortree=1982 /SigmaFactorBS="aaaattcctcgcgtttttctGGTTTTACtttgatgtaagctT GTAATACGATCATGTAAATctcctccgtcgttatgcgaatttattgttcgaatttcat c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 complement(439613..439632) /Source="Nicolas_upshift_promotors" /id="U296" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.573426573426573" /psig=1 /xcortree=1945 /SigmaFactorBS="acaattagaatgacaattttactatataagggttttTCCTTT ACctcatttagaataCATGTTACATTTAGTTCGATgaaattcgaacaataaattcgca t" /listShort="ycnE, ycnD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(439629) /Source="Nicolas_upshifts" /id="U296" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.573426573426573" /psig=1 /xcortree=1945 /SigmaFactorBS="acaattagaatgacaattttactatataagggttttTCCTTT ACctcatttagaataCATGTTACATTTAGTTCGATgaaattcgaacaataaattcgca t" /listShort="ycnE, ycnD" /GFF_Attribute="listLong" promotor_-35 complement(439646..439653) /Source="Nicolas_upshift_promotors" /id="U296" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.573426573426573" /psig=1 /xcortree=1945 /SigmaFactorBS="acaattagaatgacaattttactatataagggttttTCCTTT ACctcatttagaataCATGTTACATTTAGTTCGATgaaattcgaacaataaattcgca t" /listShort="ycnE, ycnD" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 439674..439681 /Source="Nicolas_upshift_promotors" /id="U297" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.614385614385614" /psig="0.955044955044955" /xcortree=576 /SigmaFactorBS="taacatgtattctaaatgaggtaaaggaaaaacccttatata gtaaaaTTGTCATTctaattgttgTATGATACATTTGTGTCATGaacattccaaacca t" /listShort="yczG" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 439686 /Source="Nicolas_upshifts" /id="U297" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.614385614385614" /psig="0.955044955044955" /xcortree=576 /SigmaFactorBS="taacatgtattctaaatgaggtaaaggaaaaacccttatata gtaaaaTTGTCATTctaattgttgTATGATACATTTGTGTCATGaacattccaaacca t" /listShort="yczG" /GFF_Attribute="listLong" promotor_-10 439692..439711 /Source="Nicolas_upshift_promotors" /id="U297" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.614385614385614" /psig="0.955044955044955" /xcortree=576 /SigmaFactorBS="taacatgtattctaaatgaggtaaaggaaaaacccttatata gtaaaaTTGTCATTctaattgttgTATGATACATTTGTGTCATGaacattccaaacca t" /listShort="yczG" /GFF_Attribute="listLong" /label="promotor_-10" CDS 439709..440023 /gene="yczG" /locus_tag="BSU_03880" /old_locus_tag="BSU03880" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative transcriptional regulator (ArsR family)" /protein_id="NP_388270.1" /db_xref="EnsemblGenomes-Gn:BSU03880" /db_xref="EnsemblGenomes-Tr:CAB12196" /db_xref="GOA:O31480" /db_xref="InterPro:IPR001845" /db_xref="InterPro:IPR011991" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG12781" /db_xref="UniProtKB/Swiss-Prot:O31480" /translation="MNIPNHPETETLQLTKVLHALSDPLRLELVKQLAEAKEKTCSTC ADVQVAKSTLSHHFKVLRESGIAQVRIEGKRRYYSLRAEDLEKAFPGLLEAVLNVDQD RW*" gene 439709..440023 /gene="yczG" /locus_tag="BSU_03880" /old_locus_tag="BSU03880" downshifts 440015 /Source="Nicolas_upshifts" /id="D172" /incds=0 /nref=173 /ntot=262 /MaxReadThrough="0.52252" /MaxDrop="5.32898" /score="20.7855667" /energy="-7.4" /TU="NA" /idTUdmin="U297" /TUdmin=0 /isTUend="TRUE" CDS complement(440025..441464) /gene="gabR" /locus_tag="BSU_03890" /old_locus_tag="BSU03890" /experiment="publication(s) with functional evidences, PMID:15223311, 24127574, 25388514, 27640111, 28348215, 28412355" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15223311, 24127574, 25388514, 27640111, 28348215, 28412355; Product type r : regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator (GntR/MocR family) with PLP binding site (GabR-GABA-PLP aldimine)" /protein_id="NP_388271.1" /db_xref="EnsemblGenomes-Gn:BSU03890" /db_xref="EnsemblGenomes-Tr:CAB12197" /db_xref="GOA:P94426" /db_xref="InterPro:IPR000524" /db_xref="InterPro:IPR004839" /db_xref="InterPro:IPR015421" /db_xref="InterPro:IPR015422" /db_xref="InterPro:IPR015424" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="PDB:4MGR" /db_xref="PDB:4N0B" /db_xref="PDB:4TV7" /db_xref="PDB:5T4J" /db_xref="PDB:5T4K" /db_xref="PDB:5X03" /db_xref="SubtiList:BG12042" /db_xref="UniProtKB/Swiss-Prot:P94426" /translation="MDITITLDRSEQADYIYQQIYQKLKKEILSRNLLPHSKVPSKRE LAENLKVSVNSVNSAYQQLLAEGYLYAIERKGFFVEELDMFSAEEHPPFALPDDLKEI HIDQSDWISFSHMSSDTDHFPIKSWFRCEQKAASRSYRTLGDMSHPQGIYEVRAAITR LISLTRGVKCRPEQMIIGAGTQVLMQLLTELLPKEAVYAMEEPGYRRMYQLLKNAGKQ VKTIMLDEKGMSIAEITRQQPDVLVTTPSHQFPSGTIMPVSRRIQLLNWAAEEPRRYI IEDDYDSEFTYDVDSIPALQSLDRFQNVIYMGTFSKSLLPGLRISYMVLPPELLRAYK QRGYDLQTCSSLTQLTLQEFIESGEYQKHIKKMKQHYKEKRERLITALEAEFSGEVTV KGANAGLHFVTEFDTRRTEQDILSHAAGLQLEIFGMSRFNLKENKRQTGRPALIIGFA RLKEEDIQEGVQRLFKAVYGHKKIPVTGD*" gene complement(440025..441464) /gene="gabR" /locus_tag="BSU_03890" /old_locus_tag="BSU03890" promotor_-10 complement(440349..440360) /Source="Nicolas_upshift_promotors" /id="U298" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=919 /SigmaFactorBS="cctgcaggaatttatcgagtctggtgaatatcagaAGCATAT aaaaaaaatgaagCAGCATTATAAAgaaaagagagaacgcctgatcaccgctttagaa g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(440355) /Source="Nicolas_upshifts" /id="U298" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=919 /SigmaFactorBS="cctgcaggaatttatcgagtctggtgaatatcagaAGCATAT aaaaaaaatgaagCAGCATTATAAAgaaaagagagaacgcctgatcaccgctttagaa g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(440374..440380) /Source="Nicolas_upshift_promotors" /id="U298" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=919 /SigmaFactorBS="cctgcaggaatttatcgagtctggtgaatatcagaAGCATAT aaaaaaaatgaagCAGCATTATAAAgaaaagagagaacgcctgatcaccgctttagaa g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(441507..441526) /Source="Nicolas_upshift_promotors" /id="U299" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.728271728271728" /psig="0.999000999001" /xcortree=2992 /SigmaFactorBS="tcatgtgaatatccccctgtcggtattttcTTATCATTctga cttctcTTTGGTATGATGAAAAGTACcaattataactttttgatggtatcagaaggag a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 441508..441515 /Source="Nicolas_upshift_promotors" /id="U300" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.537462537462537" /psig="0.942057942057942" /xcortree=377 /SigmaFactorBS="ttctccttctgataccatcaaaaagttataattggTACTTTT CatcataccaaagaGAAGTCAGAATGATAAGAAAataccgacagggggatattcacat g" /listShort="gabT" /GFF_Attribute="listLong" /label="promotor_-35" upshifts complement(441514) /Source="Nicolas_upshifts" /id="U299" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.728271728271728" /psig="0.999000999001" /xcortree=2992 /SigmaFactorBS="tcatgtgaatatccccctgtcggtattttcTTATCATTctga cttctcTTTGGTATGATGAAAAGTACcaattataactttttgatggtatcagaaggag a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 441529..441548 /Source="Nicolas_upshift_promotors" /id="U300" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.537462537462537" /psig="0.942057942057942" /xcortree=377 /SigmaFactorBS="ttctccttctgataccatcaaaaagttataattggTACTTTT CatcataccaaagaGAAGTCAGAATGATAAGAAAataccgacagggggatattcacat g" /listShort="gabT" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 441533 /Source="Nicolas_upshifts" /id="U300" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.537462537462537" /psig="0.942057942057942" /xcortree=377 /SigmaFactorBS="ttctccttctgataccatcaaaaagttataattggTACTTTT CatcataccaaagaGAAGTCAGAATGATAAGAAAataccgacagggggatattcacat g" /listShort="gabT" /GFF_Attribute="listLong" promotor_-35 complement(441537..441544) /Source="Nicolas_upshift_promotors" /id="U299" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.728271728271728" /psig="0.999000999001" /xcortree=2992 /SigmaFactorBS="tcatgtgaatatccccctgtcggtattttcTTATCATTctga cttctcTTTGGTATGATGAAAAGTACcaattataactttttgatggtatcagaaggag a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" CDS 441571..442881 /gene="gabT" /locus_tag="BSU_03900" /old_locus_tag="BSU03900" /EC_number="2.6.1.19" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:4590473, 12123465, 12354229, 15590624, 9723923, 19854901, 24529384" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 4590473, 12123465, 12354229, 15590624, 9723923, 19854901, 24529384; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="4-aminobutyrate aminotransferase" /protein_id="NP_388272.1" /db_xref="EnsemblGenomes-Gn:BSU03900" /db_xref="EnsemblGenomes-Tr:CAB12198" /db_xref="GOA:P94427" /db_xref="InterPro:IPR004632" /db_xref="InterPro:IPR005814" /db_xref="InterPro:IPR015421" /db_xref="InterPro:IPR015422" /db_xref="InterPro:IPR015424" /db_xref="SubtiList:BG12043" /db_xref="UniProtKB/Swiss-Prot:P94427" /translation="MSQTTASITTAQWQQKRDQFVSKGVSNGNRSLAVKGEGAELYDL DGRRFIDFAGAIGTLNVGHSHPKVVEAVKRQAEELIHPGFNVMMYPTYIELAEKLCGI APGSHEKKAIFLNSGAEAVENAVKIARKYTKRQGVVSFTRGFHGRTNMTMSMTSKVKP YKFGFGPFAPEVYQAPFPYYYQKPAGMSDESYDDMVIQAFNDFFIASVAPETVACVVM EPVQGEGGFIIPSKRFVQHVASFCKEHGIVFVADEIQTGFARTGTYFAIEHFDVVPDL ITVSKSLAAGLPLSGVIGRAEMLDAAAPGELGGTYAGSPLGCAAALAVLDIIEEEGLN ERSEEIGKIIEDKAYEWKQEFPFIGDIRRLGAMAAIEIVKDPDTREPDKTKAAAIAAY ANQNGLLLLTAGINGNIIRFLTPLVISDSLLNEGLSILEAGLRA*" gene 441571..442881 /gene="gabT" /locus_tag="BSU_03900" /old_locus_tag="BSU03900" promotor_-35 442759..442765 /Source="Nicolas_upshift_promotors" /id="U301" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=250 /SigmaFactorBS="cagcagcgatcgcggcctatgcgaatcaaaacGGATTACttt tgctgacagcGGGAATTAACGGTAATATCatccgctttttgacaccgctcgtcatctc a" /listShort="gabD" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 442779..442797 /Source="Nicolas_upshift_promotors" /id="U301" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=250 /SigmaFactorBS="cagcagcgatcgcggcctatgcgaatcaaaacGGATTACttt tgctgacagcGGGAATTAACGGTAATATCatccgctttttgacaccgctcgtcatctc a" /listShort="gabD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 442787 /Source="Nicolas_upshifts" /id="U301" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=250 /SigmaFactorBS="cagcagcgatcgcggcctatgcgaatcaaaacGGATTACttt tgctgacagcGGGAATTAACGGTAATATCatccgctttttgacaccgctcgtcatctc a" /listShort="gabD" /GFF_Attribute="listLong" promotor_-35 442883..442890 /Source="Nicolas_upshift_promotors" /id="U302" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.987012987012987" /psig="0.998001998001998" /xcortree=2034 /SigmaFactorBS="catcttggaggcgggcctgcgagcttaatCATTGGAAagaaa atggccgggTCTGCTATCATTTTAAGTAAtcatgaaaagaaaggaatgttcaatatgc c" /listShort="gabD" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 442905..442924 /Source="Nicolas_upshift_promotors" /id="U302" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.987012987012987" /psig="0.998001998001998" /xcortree=2034 /SigmaFactorBS="catcttggaggcgggcctgcgagcttaatCATTGGAAagaaa atggccgggTCTGCTATCATTTTAAGTAAtcatgaaaagaaaggaatgttcaatatgc c" /listShort="gabD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 442914 /Source="Nicolas_upshifts" /id="U302" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.987012987012987" /psig="0.998001998001998" /xcortree=2034 /SigmaFactorBS="catcttggaggcgggcctgcgagcttaatCATTGGAAagaaa atggccgggTCTGCTATCATTTTAAGTAAtcatgaaaagaaaggaatgttcaatatgc c" /listShort="gabD" /GFF_Attribute="listLong" CDS 442950..444338 /gene="gabD" /locus_tag="BSU_03910" /old_locus_tag="BSU03910" /EC_number="1.2.1.24" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:12354229, 15590624, 9723923, 12123465, 24529384, 24809290, 25911692" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12354229, 15590624, 9723923, 12123465, 24529384, 24809290, 25911692; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="succinate-semialdehyde dehydrogenase" /protein_id="NP_388273.1" /db_xref="EnsemblGenomes-Gn:BSU03910" /db_xref="EnsemblGenomes-Tr:CAB12199" /db_xref="GOA:P94428" /db_xref="InterPro:IPR010102" /db_xref="InterPro:IPR012394" /db_xref="InterPro:IPR015590" /db_xref="InterPro:IPR016160" /db_xref="InterPro:IPR016161" /db_xref="InterPro:IPR016162" /db_xref="SubtiList:BG12044" /db_xref="UniProtKB/Swiss-Prot:P94428" /translation="MPDQLTVYNPATGEEIKTIPQQSATEVEEAIERSHQAFKTWSKT SANERTSLLKKWYELIVEHKEELADLITKENGKPYQEAVGEVLYGAGYIEWFAEEAKR VYGRTVPAPTTGKRIVVTRQPVGPVAAITPWNFPNAMITRKAAPALAAGCTFIIKPAP DTPLSAYELARLAYEAGIPKDVLQVVIGDGEEIGNVFTSSPKIRKITFTGSTPVGKIL MKNSADTVKHVSMELGGHAPLIVDEDADIDLAVEQAMASKYRNAGQTCVCANRLIVHE SIKDEFAAKLSEQVSKLKVGNGLEEGVNVGPIINKRGFEKIVSQIDDAVEKGAKVIAG GTYDRNDDKGCYFVNPTVLTDVDTSMNIMHEETFGPVAPIVTFSDIDEAIQLANDTPY GLAAYFFTENYRRGIYISENLEYGIIGWNDGGPSAVQAPFGGMKESGIGREGGSEGIE PYLETKYLSIGL*" gene 442950..444338 /gene="gabD" /locus_tag="BSU_03910" /old_locus_tag="BSU03910" downshifts 444346 /Source="Nicolas_upshifts" /id="D173" /incds=0 /nref=107 /ntot=240 /MaxReadThrough="0.105510000000001" /MaxDrop="6.52053" /score="38.677658" /energy="-19.9" /TU="NA" /idTUdmin="U301" /TUdmin="-3" /isTUend="TRUE" promotor_-35 444396..444402 /Source="Nicolas_upshift_promotors" /id="U303" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=885 /SigmaFactorBS="gagctgccggattttccggcagctctttttgtgttccggCGA ATAAtcacaacaattccAGCCAAAATAACagcaaatacattttgaaagaaggttcccc a" /listShort="glcU, gdh" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 444416..444427 /Source="Nicolas_upshift_promotors" /id="U303" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=885 /SigmaFactorBS="gagctgccggattttccggcagctctttttgtgttccggCGA ATAAtcacaacaattccAGCCAAAATAACagcaaatacattttgaaagaaggttcccc a" /listShort="glcU, gdh" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 444417 /Source="Nicolas_upshifts" /id="U303" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=885 /SigmaFactorBS="gagctgccggattttccggcagctctttttgtgttccggCGA ATAAtcacaacaattccAGCCAAAATAACagcaaatacattttgaaagaaggttcccc a" /listShort="glcU, gdh" /GFF_Attribute="listLong" CDS 444461..445324 /gene="glcU" /locus_tag="BSU_03920" /old_locus_tag="BSU03920" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 10438764, 15849754, 16850406, 19054326, 21564334, 27329749; Product type t : transporter" /codon_start=1 /transl_table=11 /product="glucose uptake protein" /protein_id="NP_388274.1" /db_xref="EnsemblGenomes-Gn:BSU03920" /db_xref="EnsemblGenomes-Tr:CAB12200" /db_xref="GOA:P40420" /db_xref="InterPro:IPR010651" /db_xref="SubtiList:BG11066" /db_xref="UniProtKB/Swiss-Prot:P40420" /translation="MDLLLALLPALFWGSIVLFNVKLGGGPYSQTLGTTIGALIVSIV IYFFVQPVLSLRIFIVGIVSGLFWSLGQANQLKSIQLMGVSKTMPISTGMQLVSTSLF GVIVFREWSTPIAITLGVLALIFIIVGIILTSLEDKNDKKEGEPSNLKKGILILLVST LGYLVYVVVARLFNVSGWSALLPQAIGMVVGGLVLTYRHKPFNKYAIRNILPGLIWAG GNMFLFISQPRVGVATSFSLSQMGIVISTLGGIFILREKKTKRQLIAIAIGIILIIAA AVFLGIAKTNS*" gene 444461..445324 /gene="glcU" /locus_tag="BSU_03920" /old_locus_tag="BSU03920" CDS 445344..446129 /gene="gdh" /locus_tag="BSU_03930" /old_locus_tag="BSU03930" /EC_number="1.1.1.47" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:2493633, 3141376, 6438057, 16912926" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 2493633, 3141376, 6438057, 16912926; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="forespore glucose 1-dehydrogenase" /protein_id="NP_388275.1" /db_xref="EnsemblGenomes-Gn:BSU03930" /db_xref="EnsemblGenomes-Tr:CAB12201" /db_xref="GOA:P12310" /db_xref="InterPro:IPR002347" /db_xref="InterPro:IPR020904" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG10545" /db_xref="UniProtKB/Swiss-Prot:P12310" /translation="MYPDLKGKVVAITGAASGLGKAMAIRFGKEQAKVVINYYSNKQD PNEVKEEVIKAGGEAVVVQGDVTKEEDVKNIVQTAIKEFGTLDIMINNAGLENPVPSH EMPLKDWDKVIGTNLTGAFLGSREAIKYFVENDIKGNVINMSSVHEVIPWPLFVHYAA SKGGIKLMTETLALEYAPKGIRVNNIGPGAINTPINAEKFADPKQKADVESMIPMGYI GEPEEIAAVAAWLASKEASYVTGITLFADGGMTQYPSFQAGRG*" gene 445344..446129 /gene="gdh" /locus_tag="BSU_03930" /old_locus_tag="BSU03930" misc_feature 445449..445468 /Source="Nicolas_upshift_promotors" /id="U304" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.692307692307692" /psig="0.732267732267732" /xcortree=1477 /SigmaFactorBS="gcttcagggctcggaaaggcgatggccattcgcttcggcaag gagcaggcaaaagtggttATCAACTATTATAGTAATAAacaagatccgaacgaggtaa a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 445449 /Source="Nicolas_upshifts" /id="U304" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.692307692307692" /psig="0.732267732267732" /xcortree=1477 /SigmaFactorBS="gcttcagggctcggaaaggcgatggccattcgcttcggcaag gagcaggcaaaagtggttATCAACTATTATAGTAATAAacaagatccgaacgaggtaa a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" downshifts 445537 /Source="Nicolas_upshifts" /id="D174" /incds=1 /nref=1 /ntot=3 /MaxReadThrough="6.44884" /MaxDrop="2.47712" /score="-5.4075438" /energy="-11.7" /TU="U303" /idTUdmin="U301" /TUdmin=1188 /isTUend="FALSE" downshifts 446131 /Source="Nicolas_upshifts" /id="D175" /incds=0 /nref=4 /ntot=40 /MaxReadThrough="2.7861" /MaxDrop="4.2307" /score="-5.4075438" /energy="-11.7" /TU="U303" /idTUdmin="U303" /TUdmin="-836" /isTUend="FALSE" CDS complement(446174..446788) /gene="cutI" /locus_tag="BSU_03940" /old_locus_tag="BSU03940" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 19168619, 22904286, 27010565, 26822828; Product type f: factor" /codon_start=1 /transl_table=11 /product="putative membrane protein involved in copper intake" /protein_id="NP_388276.1" /db_xref="EnsemblGenomes-Gn:BSU03940" /db_xref="EnsemblGenomes-Tr:CAB12202" /db_xref="GOA:P94431" /db_xref="InterPro:IPR012533" /db_xref="SubtiList:BG12045" /db_xref="UniProtKB/Swiss-Prot:P94431" /translation="MLKKIALTLCPAIVGSLLFFTAPASAHVSVKPAESAAGSWETYT MKVPSEKNLPTTKVVLKMPKDVEFQQYEPIPGWKVSTQKHDDKSVSVTWEATDGGIQE GQFQQFTFVAKNPDKAEEAAWDAYQYYKDGSIVEWTGDEDADTPHSITNITSAKQVTD EHGATKTEDDSENSGSSALDITAMVLSAAAIILSVAALVKKKRA*" gene complement(446174..446788) /gene="cutI" /locus_tag="BSU_03940" /old_locus_tag="BSU03940" downshifts complement(446185) /Source="Nicolas_upshifts" /id="D176" /incds=0 /nref=95 /ntot=219 /MaxReadThrough="0.879290000000001" /MaxDrop="6.67627" /score="21.5633403" /energy="-16" /TU="NA" /idTUdmin="U305" /TUdmin=0 /isTUend="TRUE" CDS complement(446801..448426) /gene="cutJ" /locus_tag="BSU_03950" /old_locus_tag="BSU03950" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:15101989, 15849754, 16850406, 19168619, 22904286, 23012364" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15101989, 15849754, 16850406, 19168619, 22904286, 23012364; Product type t : transporter" /codon_start=1 /transl_table=11 /product="copper import permease subunit" /protein_id="NP_388277.2" /db_xref="EnsemblGenomes-Gn:BSU03950" /db_xref="EnsemblGenomes-Tr:CAB12203" /db_xref="GOA:C0SP95" /db_xref="InterPro:IPR007348" /db_xref="InterPro:IPR008457" /db_xref="InterPro:IPR013783" /db_xref="InterPro:IPR014756" /db_xref="InterPro:IPR032693" /db_xref="InterPro:IPR032694" /db_xref="SubtiList:BG12046" /db_xref="UniProtKB/Swiss-Prot:C0SP95" /translation="MKRNRWWIILLLFLVFLPKTSFAHAYIVKSSPGENSELKSAPAQ VEIEFNEPVEEGFHYIKVYNSNGDRVDTDKTEIKKDNHHIMTVKLKKNLPKDVYRAEW NAVSADGHPVSGVIPFSIGKADGGFSSQKAADSALNPGTAADRAILYTALSLFIGTVF FHLFWYKGKSEQLVKRTRRILTGSIAALGLALLLQLPIQTKANAGGGWGSAFQPGYIR ETLFETAGGSIWIIQAALFVLLALSVIPAIRKNRFSSFGYWTAPLIFFFGLLLAKAFT GHAAVVEEKTVGILMDFLHLTSASIWVGGIAALVLLLSKEWRQPDKTLAWETVRRFSP WALTAVGVILFSGLLNGFFIIRSMDSLFHTAYGQALLVKSGLFVFMLVLGAIHFLLTR KQRRTGISRTLKAEWAIGIAVLITAAVFTSLPSPPEPAPEPFYQTKAIENGQSVSLSI SPNQPGKNVFELRVTDHNGDPVKNIQQITLTVYKTGLSGSENKSTFTLKEKTKGVFQD QNLSINEKGNWKIKVHGLTGDFNEINIMFTKTN*" gene complement(446801..448426) /gene="cutJ" /locus_tag="BSU_03950" /old_locus_tag="BSU03950" CDS complement(448461..449033) /gene="cutR" /locus_tag="BSU_03960" /old_locus_tag="BSU03960" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:15101989, 22904286, 23012364" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15101989, 22904286, 23012364; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator of copper intake (CutR-Cu(+))" /protein_id="NP_388278.1" /db_xref="EnsemblGenomes-Gn:BSU03960" /db_xref="EnsemblGenomes-Tr:CAB12204" /db_xref="GOA:P94433" /db_xref="InterPro:IPR001034" /db_xref="InterPro:IPR008719" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG12047" /db_xref="UniProtKB/Swiss-Prot:P94433" /translation="MLPINRQQHILKWLKEEGSLRISDISARFGVSEMTVYRDVNQLV QSNQVIKTAGGITLPVRTPQTDHMCSYCLKPVNQAHSVQLITVNQDIEQLCCAHCAFL RYADKTEEVSHLICRDFLLQTTVSAGSAYFVVNAELNLHCCQPQAIPFATLDHAERFQ KGFGGAVCTFDQALEDMLQDRKKRCTCTKK*" gene complement(448461..449033) /gene="cutR" /locus_tag="BSU_03960" /old_locus_tag="BSU03960" promotor_-10 complement(449055..449074) /Source="Nicolas_upshift_promotors" /id="U305" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.944055944055944" /psig="0.999000999001" /xcortree=1591 /SigmaFactorBS="tgttcaacacattttcacattttttatcatccactTACTTGT CtccgtctctaaaaTCCTCTACGCTTAAATAGATcttaatgaagagggtgtatgaatg c" /listShort="ycnK, ycnJ, ycnI" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(449070) /Source="Nicolas_upshifts" /id="U305" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.944055944055944" /psig="0.999000999001" /xcortree=1591 /SigmaFactorBS="tgttcaacacattttcacattttttatcatccactTACTTGT CtccgtctctaaaaTCCTCTACGCTTAAATAGATcttaatgaagagggtgtatgaatg c" /listShort="ycnK, ycnJ, ycnI" /GFF_Attribute="listLong" promotor_-35 complement(449088..449095) /Source="Nicolas_upshift_promotors" /id="U305" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.944055944055944" /psig="0.999000999001" /xcortree=1591 /SigmaFactorBS="tgttcaacacattttcacattttttatcatccactTACTTGT CtccgtctctaaaaTCCTCTACGCTTAAATAGATcttaatgaagagggtgtatgaatg c" /listShort="ycnK, ycnJ, ycnI" /GFF_Attribute="listLong" /label="promotor_-35" misc_feature 449155..449174 /Source="Nicolas_upshift_promotors" /id="U306" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.764235764235764" /psig="0.999000999001" /xcortree=2504 /SigmaFactorBS="aaaaatgtgaaaatgtgttgaacagcaacaaaacgaaacaga agggacTCTGGTATAATAGACAGATGgaatagaaagtgaggaataccctatgaaagaa a" /listShort="ycnL" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 449167 /Source="Nicolas_upshifts" /id="U306" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.764235764235764" /psig="0.999000999001" /xcortree=2504 /SigmaFactorBS="aaaaatgtgaaaatgtgttgaacagcaacaaaacgaaacaga agggacTCTGGTATAATAGACAGATGgaatagaaagtgaggaataccctatgaaagaa a" /listShort="ycnL" /GFF_Attribute="listLong" CDS 449198..449551 /gene="ycnL" /locus_tag="BSU_03970" /old_locus_tag="BSU03970" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406, 18307109, 27010565; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative reductase or disulfide isomerase" /protein_id="NP_388279.1" /db_xref="EnsemblGenomes-Gn:BSU03970" /db_xref="EnsemblGenomes-Tr:CAB12205" /db_xref="GOA:P94434" /db_xref="SubtiList:BG12048" /db_xref="UniProtKB/Swiss-Prot:P94434" /translation="MKETPCPNCGKPLTGDMVRSSNVPCQFRCGHCRERLYEYKVSAP IMLVSLAAIVLLIYLLMLLRNAAGSVLPAVQHVPMAVFALVCAYPVFIVSERMIAKYV IQNGNIIYRGKRKGS*" gene 449198..449551 /gene="ycnL" /locus_tag="BSU_03970" /old_locus_tag="BSU03970" downshifts 449522 /Source="Nicolas_upshifts" /id="D177" /incds=0 /nref=136 /ntot=248 /MaxReadThrough="0.860829999999999" /MaxDrop="6.25982" /score="38.4886131" /energy="-13.4" /TU="NA" /idTUdmin="U306" /TUdmin="-19" /isTUend="TRUE" promotor_-35 449615..449622 /Source="Nicolas_upshift_promotors" /id="U307" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.938061938061938" /psig=1 /xcortree=1546 /SigmaFactorBS="tgtcacagtcatgtgccaaagtcctctttactttCAATTGTA tagggactgtaagCGTTTTAACATAGAGTCAAAgggaagcatcattctctgaacatat t" /listShort="S132, mtlA, mtlF, mtlD, ycsA, sipU, S133" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 449636..449655 /Source="Nicolas_upshift_promotors" /id="U307" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.938061938061938" /psig=1 /xcortree=1546 /SigmaFactorBS="tgtcacagtcatgtgccaaagtcctctttactttCAATTGTA tagggactgtaagCGTTTTAACATAGAGTCAAAgggaagcatcattctctgaacatat t" /listShort="S132, mtlA, mtlF, mtlD, ycsA, sipU, S133" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 449641 /Source="Nicolas_upshifts" /id="U307" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.938061938061938" /psig=1 /xcortree=1546 /SigmaFactorBS="tgtcacagtcatgtgccaaagtcctctttactttCAATTGTA tagggactgtaagCGTTTTAACATAGAGTCAAAgggaagcatcattctctgaacatat t" /listShort="S132, mtlA, mtlF, mtlD, ycsA, sipU, S133" /GFF_Attribute="listLong" S_feature 449651..449723 /Source="Nicolas_S_feature" /locus_tag="new_449651_449723" /HighExp="S0, dia5, Gly, G135, B60, T0.30H, BT, G180, G150, M40t45" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S132" CDS 449724..451160 /gene="mtlA" /locus_tag="BSU_03981" /old_locus_tag="BSU03981" /EC_number="2.7.1.197" /function="16.1: Circulate" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:12897001, 23279188" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12897001, 23279188; Product type t: transporter" /codon_start=1 /transl_table=11 /product="phosphotransferase system (PTS) mannitol-specific enzyme IICB component" /protein_id="NP_388280.2" /db_xref="EnsemblGenomes-Gn:BSU03981" /db_xref="EnsemblGenomes-Tr:CAB12206" /db_xref="GOA:P42956" /db_xref="InterPro:IPR003352" /db_xref="InterPro:IPR003501" /db_xref="InterPro:IPR004718" /db_xref="InterPro:IPR013011" /db_xref="InterPro:IPR013014" /db_xref="InterPro:IPR029503" /db_xref="InterPro:IPR036095" /db_xref="SubtiList:BG11215" /db_xref="UniProtKB/Swiss-Prot:P42956" /translation="MQQQEQQQGGMKVKVQRFGSYLSGMIMPNIGAFIAWGIITALFI PAGWFPNEQLNTLVSPMITYLLPLLIAYTGGKMIYDHRGGVVGATAAIGVIVGSDIPM FLGAMIMGPLGGYLIKQTDKLFKDKVKQGFEMLINNFTAGIVGAALTILAFYAIGPVV LTLNKLLAAGVEVIVHANLLPVASVFVEPAKVLFLNNAINHGILSPIGIEQASQTGKS ILFLVEANPGPGLGILLAYMFFGKGSSKSTAPGAAIIHFFGGIHEIYFPYILMKPALI LAAIAGGASGLLTFTIFNAGLVAAASPGSIIALMAMTPRGGYFGVLAGVLVAAAVSFI VSAVILKSSKASEEDLAAATEKMQSMKGKKSQAAAALEAEQAKAEEASELSPESVNKI IFACDAGMGSSAMGASILRNKVKKAELDISVTNTAINNLPSDADIVITHKDLTDRAKA KLPNATHISVDNFLNSPKYDELIEKLKK*" gene 449724..451160 /gene="mtlA" /locus_tag="BSU_03981" /old_locus_tag="BSU03981" CDS 451185..451616 /gene="mtlF" /locus_tag="BSU_03982" /old_locus_tag="BSU03982" /EC_number="2.7.1.197" /function="16.1: Circulate" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:12897001, 23279188" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12897001, 23279188; Product type t: transporter" /codon_start=1 /transl_table=11 /product="phosphotransferase system (PTS) mannitol-specific enzyme IIA component" /protein_id="YP_003097678.1" /db_xref="EnsemblGenomes-Gn:BSU03982" /db_xref="EnsemblGenomes-Tr:CAX52549" /db_xref="GOA:C0H3V2" /db_xref="InterPro:IPR002178" /db_xref="InterPro:IPR016152" /db_xref="UniProtKB/Swiss-Prot:C0H3V2" /translation="MQVLAKENIKLNQTVSSKEEAIKLAGQTLIDNGYVTEDYISKMF EREETSSTFMGNFIAIPHGTEEAKSEVLHSGISIIQIPEGVEYGEGNTAKVVFGIAGK NNEHLDILSNIAIICSEEENIERLISAKSEEDLIAIFNEVN*" gene 451185..451616 /gene="mtlF" /locus_tag="BSU_03982" /old_locus_tag="BSU03982" CDS 451618..452739 /gene="mtlD" /locus_tag="BSU_03990" /old_locus_tag="BSU03990" /EC_number="1.1.1.17" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:12897001, 22014119, 23279188" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12897001, 22014119, 23279188; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="mannitol-1-phosphate 5-dehydrogenase" /protein_id="NP_388281.2" /db_xref="EnsemblGenomes-Gn:BSU03990" /db_xref="EnsemblGenomes-Tr:CAB12207" /db_xref="GOA:P42957" /db_xref="InterPro:IPR000669" /db_xref="InterPro:IPR008927" /db_xref="InterPro:IPR013118" /db_xref="InterPro:IPR013131" /db_xref="InterPro:IPR013328" /db_xref="InterPro:IPR023027" /db_xref="InterPro:IPR023028" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG11216" /db_xref="UniProtKB/Swiss-Prot:P42957" /translation="MIALHFGAGNIGRGFIGALLHHSGYDVVFADVNETMVSLLNEKK EYTVELAEEGRSSEIIGPVSAINSGSQTEELYRLMNEAALITTAVGPNVLKLIAPSIA EGLRRRNTANTLNIIACENMIGGSSFLKKEIYSHLTEAEQKSVSETVGFPNSAVDRIV PIQHHEDPLKVSVEPFFEWVIDESGFKGKTPVINGALFVDDLTPYIERKLFTVNTGHA VTAYVGYQRGLKTVKEAIDHPEIRRVVHSALLETGDYLVKSYGFKQTEHEQYIKKIIG RFENPFISDDVTRVARSPLRKLGENDRLVGPAKKIKEPNALAEGIAAALRFDFTGDPE AVELQALIEEKGYSGVLQEVCGIQSHEPLHAIILKKLNQ*" gene 451618..452739 /gene="mtlD" /locus_tag="BSU_03990" /old_locus_tag="BSU03990" downshifts 452722 /Source="Nicolas_upshifts" /id="D178" /incds=0 /nref=46 /ntot=156 /MaxReadThrough="5.56503" /MaxDrop="4.72154" /score="32.3837677" /energy="-13.4" /TU="U307" /idTUdmin="U308" /TUdmin="-1254" /isTUend="FALSE" promotor_-35 452768..452771 /Source="Nicolas_upshift_promotors" /id="U308" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.964035964035964" /psig=1 /xcortree=1552 /SigmaFactorBS="ttaatcaataaccgaccacccgtgacacaatgtcacgggCTT TttttactatctcgcaATCTAGTATAATAGAAAGCGcttacgataacaggggaaggag a" /listShort="ycsA" /listLong="sipU, S133, ycsD" /label="promotor_-35" promotor_-10 452787..452806 /Source="Nicolas_upshift_promotors" /id="U308" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.964035964035964" /psig=1 /xcortree=1552 /SigmaFactorBS="ttaatcaataaccgaccacccgtgacacaatgtcacgggCTT TttttactatctcgcaATCTAGTATAATAGAAAGCGcttacgataacaggggaaggag a" /listShort="ycsA" /listLong="sipU, S133, ycsD" /label="promotor_-10" upshifts 452789 /Source="Nicolas_upshifts" /id="U308" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.964035964035964" /psig=1 /xcortree=1552 /SigmaFactorBS="ttaatcaataaccgaccacccgtgacacaatgtcacgggCTT TttttactatctcgcaATCTAGTATAATAGAAAGCGcttacgataacaggggaaggag a" /listShort="ycsA" /listLong="sipU, S133, ycsD" CDS 452830..453894 /gene="ycsA" /locus_tag="BSU_04000" /old_locus_tag="BSU04000" /EC_number="1.1.1.93" /EC_number="1.1.1.83" /EC_number="4.1.1.73" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 10568751, 12356321; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative tartrate dehydrogenase" /protein_id="NP_388282.3" /db_xref="EnsemblGenomes-Gn:BSU04000" /db_xref="EnsemblGenomes-Tr:CAB12208" /db_xref="GOA:P42958" /db_xref="InterPro:IPR011829" /db_xref="InterPro:IPR019818" /db_xref="InterPro:IPR024084" /db_xref="SubtiList:BG11222" /db_xref="UniProtKB/Swiss-Prot:P42958" /translation="MTMKQFEIAAIPGDGVGKEVVAAAEKVLHTAAEVHGGLSFSFTA FPWSCDYYLEHGKMMPEDGIHTLTQFEAVFLGAVGNPKLVPDHISLWGLLLKIRRELE LSINMRPAKQMAGITSPLLHPNDFDFVVIRENSEGEYSEVGGRIHRGDDEIAIQNAVF TRKATERVMRFAFELAKKRRSHVTSATKSNGIYHAMPFWDEVFQQTAADYSGIETSSQ HIDALAAFFVTRPETFDVIVASNLFGDILTDISSSLMGSIGIAPSANINPSGKYPSMF EPVHGSAPDIAGQGLANPIGQIWTAKLMLDHFGEEELGAKILDVMEQVTADGIKTRDI GGQSTTAEVTDEICSRLRKL*" gene 452830..453894 /gene="ycsA" /locus_tag="BSU_04000" /old_locus_tag="BSU04000" promotor_-35 453064..453072 /Source="Nicolas_upshift_promotors" /id="U309" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.96903096903097" /psig="0.96903096903097" /xcortree=1234 /SigmaFactorBS="atttgaagcagtttttttgggagctgtcGGAAATCCGaagct ggttcccgATCATATATCGTTATGGGGGctgctgctgaaaatccggagggagcttgag c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 453086..453105 /Source="Nicolas_upshift_promotors" /id="U309" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.96903096903097" /psig="0.96903096903097" /xcortree=1234 /SigmaFactorBS="atttgaagcagtttttttgggagctgtcGGAAATCCGaagct ggttcccgATCATATATCGTTATGGGGGctgctgctgaaaatccggagggagcttgag c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 453096 /Source="Nicolas_upshifts" /id="U309" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.96903096903097" /psig="0.96903096903097" /xcortree=1234 /SigmaFactorBS="atttgaagcagtttttttgggagctgtcGGAAATCCGaagct ggttcccgATCATATATCGTTATGGGGGctgctgctgaaaatccggagggagcttgag c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" downshifts 453888 /Source="Nicolas_upshifts" /id="D179" /incds=0 /nref=7 /ntot=41 /MaxReadThrough="4.24123" /MaxDrop="4.42639" /score="9.70532694" /energy="-11.6" /TU="U307,U308" /idTUdmin="U308" /TUdmin="-88" /isTUend="FALSE" promotor_-35 453961..453968 /Source="Nicolas_upshift_promotors" /id="U310" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.567432567432567" /psig="0.996003996003996" /xcortree=2303 /SigmaFactorBS="atttccttacgaaaatttccacgaaagTCTAACCAagcagat ccaaaTGCTGTATAATAATTTGGAAttcttaggaaagcatcgggtgaaggaagttgaa t" /listShort="sipU, S133, ycsD" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 453981..454000 /Source="Nicolas_upshift_promotors" /id="U310" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.567432567432567" /psig="0.996003996003996" /xcortree=2303 /SigmaFactorBS="atttccttacgaaaatttccacgaaagTCTAACCAagcagat ccaaaTGCTGTATAATAATTTGGAAttcttaggaaagcatcgggtgaaggaagttgaa t" /listShort="sipU, S133, ycsD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 453994 /Source="Nicolas_upshifts" /id="U310" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.567432567432567" /psig="0.996003996003996" /xcortree=2303 /SigmaFactorBS="atttccttacgaaaatttccacgaaagTCTAACCAagcagat ccaaaTGCTGTATAATAATTTGGAAttcttaggaaagcatcgggtgaaggaagttgaa t" /listShort="sipU, S133, ycsD" /GFF_Attribute="listLong" CDS 454029..454592 /gene="sipU" /locus_tag="BSU_04010" /old_locus_tag="BSU04010" /EC_number="3.4.21.89" /function="16.1: Circulate" /function="16.2: Construct biomass (Anabolism)" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:9325333, 10198007, 11856304, 14568161" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9325333, 10198007, 11856304, 14568161; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="type I signal peptidase" /protein_id="NP_388283.1" /db_xref="EnsemblGenomes-Gn:BSU04010" /db_xref="EnsemblGenomes-Tr:CAB12209" /db_xref="GOA:P42959" /db_xref="InterPro:IPR000223" /db_xref="InterPro:IPR015927" /db_xref="InterPro:IPR019756" /db_xref="InterPro:IPR019757" /db_xref="InterPro:IPR019758" /db_xref="InterPro:IPR036286" /db_xref="SubtiList:BG11223" /db_xref="UniProtKB/Swiss-Prot:P42959" /translation="MNAKTITLKKKRKIKTIVVLSIIMIAALIFTIRLVFYKPFLIEG SSMAPTLKDSERILVDKAVKWTGGFHRGDIIVIHDKKSGRSFVKRLIGLPGDSIKMKN DQLYINDKKVEEPYLKEYKQEVKESGVTLTGDFEVEVPSGKYFVMGDNRLNSLDSRNG MGMPSEDDIIGTESLVFYPFGEMRQAK*" gene 454029..454592 /gene="sipU" /locus_tag="BSU_04010" /old_locus_tag="BSU04010" S_feature 454593..455317 /Source="Nicolas_S_feature" /locus_tag="new_454593_455317" /HighExp="G150, Oxctl, Lbexp, G135, Paraq, dia0, LBGexp, Mt0, G180, dia15" /AntisenseName="yczH" /AntisenseCor="0.134432865921808" /AntisenseRegPval="-1.6" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="0.996, 1" /TUlongSig="SigA" /TUlongPSig=1 /label="S133" CDS complement(454652..455260) /gene="yczH" /locus_tag="BSU_04020" /old_locus_tag="BSU04020" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative hydrolase" /protein_id="NP_388284.2" /db_xref="EnsemblGenomes-Gn:BSU04020" /db_xref="EnsemblGenomes-Tr:CAB12210" /db_xref="GOA:O31482" /db_xref="InterPro:IPR002925" /db_xref="InterPro:IPR029058" /db_xref="SubtiList:BG12782" /db_xref="UniProtKB/Swiss-Prot:O31482" /translation="MFPKPLVILAHEIYGVNSHMKKMGRLIKMAGYDVLTPNLLGEDE VYTLKEEKTAYEQFTKHERLKTGETIIQNVIRQNAGRHIFVIGFSVGATIAWKCSSMP EVSGSVCYYGSRIRDSLHHMPACPVLLFFPNYEPSFDVALLIKKLREKQHTHLEIYQF DALHGFANPDSVYFNRALFFKTLSIIKNGAESRLRTVSSSFF*" gene complement(454652..455260) /gene="yczH" /locus_tag="BSU_04020" /old_locus_tag="BSU04020" misc_feature complement(455278..455297) /Source="Nicolas_upshift_promotors" /id="U311" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.397602397602398" /psig="0.993006993006993" /xcortree=2931 /SigmaFactorBS="aagataatgagttcattttatatctcctttttttgaccatta tatctcagcctaaagtgaaacgATAGGATATAATGGAAAAAAcacaaaaggaggccgt t" /listShort="yczH" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" promotor_-35 455294..455300 /Source="Nicolas_upshift_promotors" /id="U312" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.572427572427572" /psig="0.995004995004995" /xcortree=3001 /SigmaFactorBS="ataacggcctccttttgtgttttttccattatatcCTATCGT ttcactttaggcTGAGATATAATGGTCAAAAAaaggagatataaaatgaactcattat c" /listShort="ycsD" /GFF_Attribute="listLong" /label="promotor_-35" upshifts complement(455301) /Source="Nicolas_upshifts" /id="U311" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.397602397602398" /psig="0.993006993006993" /xcortree=2931 /SigmaFactorBS="aagataatgagttcattttatatctcctttttttgaccatta tatctcagcctaaagtgaaacgATAGGATATAATGGAAAAAAcacaaaaggaggccgt t" /listShort="yczH" /GFF_Attribute="listLong" promotor_-10 455313..455332 /Source="Nicolas_upshift_promotors" /id="U312" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.572427572427572" /psig="0.995004995004995" /xcortree=3001 /SigmaFactorBS="ataacggcctccttttgtgttttttccattatatcCTATCGT ttcactttaggcTGAGATATAATGGTCAAAAAaaggagatataaaatgaactcattat c" /listShort="ycsD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 455319 /Source="Nicolas_upshifts" /id="U312" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.572427572427572" /psig="0.995004995004995" /xcortree=3001 /SigmaFactorBS="ataacggcctccttttgtgttttttccattatatcCTATCGT ttcactttaggcTGAGATATAATGGTCAAAAAaaggagatataaaatgaactcattat c" /listShort="ycsD" /GFF_Attribute="listLong" CDS 455346..455738 /gene="ycsD" /locus_tag="BSU_04030" /old_locus_tag="BSU04030" /EC_number="4.2.1.-" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 12682299, 16291680, 22720735; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative hydroxyacyl-(acyl carrier protein) dehydratase" /protein_id="NP_388285.2" /db_xref="EnsemblGenomes-Gn:BSU04030" /db_xref="EnsemblGenomes-Tr:CAB12211" /db_xref="InterPro:IPR013114" /db_xref="InterPro:IPR029069" /db_xref="SubtiList:BG11225" /db_xref="UniProtKB/Swiss-Prot:P42961" /translation="MNSLSLPHRYPFLFIDGVTDSEPGKHAAAYKLISENDWFITDTQ TEMPFSLVIEALAQTAAFTGITDENSLGLLSSVKKAEKLGEAVPGDRLDLTFEVTRNR RGFVFGHAKASVGEQPVAEAEIGIYIEK*" gene 455346..455738 /gene="ycsD" /locus_tag="BSU_04030" /old_locus_tag="BSU04030" downshifts 455715 /Source="Nicolas_upshifts" /id="D180" /incds=0 /nref=23 /ntot=189 /MaxReadThrough="1.8721" /MaxDrop="3.42324" /score="-5.4921522" /energy="-13.6" /TU="NA" /idTUdmin="U310" /TUdmin=0 /isTUend="TRUE" CDS complement(455771..455935) /gene="yczO" /locus_tag="BSU_04039" /old_locus_tag="BSU04039" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="YP_003097679.1" /db_xref="EnsemblGenomes-Gn:BSU04039" /db_xref="EnsemblGenomes-Tr:CAX52550" /db_xref="UniProtKB/Swiss-Prot:C0H3V3" /translation="MTEKKQQNKPNENPEHNDLTDPIPNEELKENMNDEKHKRQQRDN SQSERDYDTK*" gene complement(455771..455935) /gene="yczO" /locus_tag="BSU_04039" /old_locus_tag="BSU04039" downshifts complement(455791) /Source="Nicolas_upshifts" /id="D181" /incds=0 /nref=101 /ntot=193 /MaxReadThrough="1.44096" /MaxDrop="6.55741" /score="22.582242" /energy="-10.6" /TU="NA" /idTUdmin="U313" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(455945..455963) /Source="Nicolas_upshift_promotors" /id="U313" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.992007992007992" /psig="0.992007992007992" /xcortree=206 /SigmaFactorBS="ttctaatacattatacccagcgggacaaaaaagcgatttcct aTGTTTGAggagaatgaataagAGGAAAACAAACGGTGAGGtgatcaaacatgacaga a" /listShort="yczO" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(455967) /Source="Nicolas_upshifts" /id="U313" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.992007992007992" /psig="0.992007992007992" /xcortree=206 /SigmaFactorBS="ttctaatacattatacccagcgggacaaaaaagcgatttcct aTGTTTGAggagaatgaataagAGGAAAACAAACGGTGAGGtgatcaaacatgacaga a" /listShort="yczO" /GFF_Attribute="listLong" promotor_-35 complement(455978..455984) /Source="Nicolas_upshift_promotors" /id="U313" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.992007992007992" /psig="0.992007992007992" /xcortree=206 /SigmaFactorBS="ttctaatacattatacccagcgggacaaaaaagcgatttcct aTGTTTGAggagaatgaataagAGGAAAACAAACGGTGAGGtgatcaaacatgacaga a" /listShort="yczO" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 455997..456004 /Source="Nicolas_upshift_promotors" /id="U314" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.809190809190809" /psig=1 /xcortree=2352 /SigmaFactorBS="cctcttattcattctcctcaaacataggaaatcgctTTTTTG TCccgctgggtataaTGTATTAGAATAGAGAGAAGcacaacaaaaagataaagagagg t" /listShort="ycsE" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 456018..456037 /Source="Nicolas_upshift_promotors" /id="U314" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.809190809190809" /psig=1 /xcortree=2352 /SigmaFactorBS="cctcttattcattctcctcaaacataggaaatcgctTTTTTG TCccgctgggtataaTGTATTAGAATAGAGAGAAGcacaacaaaaagataaagagagg t" /listShort="ycsE" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 456021 /Source="Nicolas_upshifts" /id="U314" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.809190809190809" /psig=1 /xcortree=2352 /SigmaFactorBS="cctcttattcattctcctcaaacataggaaatcgctTTTTTG TCccgctgggtataaTGTATTAGAATAGAGAGAAGcacaacaaaaagataaagagagg t" /listShort="ycsE" /GFF_Attribute="listLong" CDS 456068..456817 /gene="ribZ" /locus_tag="BSU_04040" /old_locus_tag="BSU04040" /EC_number="3.1.3.-" /function="4.9: Riboflavin, FMN, and FAD" /function="16.11: Scavenge (Catabolism)" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1b: Function from experimental evidences in the studied species; PubMedId: 26316208, 27435445, 27784292; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="5-amino-6-ribitylamino-2,4(1H, 3H)-pyrimidinedione 5'-phosphate phosphatase / 5' nucleotidase" /protein_id="NP_388286.2" /db_xref="EnsemblGenomes-Gn:BSU04040" /db_xref="EnsemblGenomes-Tr:CAB12212" /db_xref="GOA:P42962" /db_xref="InterPro:IPR006379" /db_xref="InterPro:IPR023214" /db_xref="InterPro:IPR036412" /db_xref="SubtiList:BG11226" /db_xref="UniProtKB/Swiss-Prot:P42962" /translation="MSVQREDVDIKLIAIDMDGTLLNDEQLISDENRKAIREAEDKGV YVVISTGRTLMTCRELAESLKLSSFLITANGSEIWDSNFNLVERKLLHTDHIQMMWDL RNKHNTNFWASTVNKVWRGEFPENITDHEWLKFGFDIEDDDIRNEVLEELRKNKELEI TNSSPTNIEVNALGINKAAALAKVTEKLGFTMENVMAMGDSLNDIAMIKEAGLGVAMG NAQDIVKETADYITDTNIEDGVAKAIRHWVL*" gene 456068..456817 /gene="ribZ" /locus_tag="BSU_04040" /old_locus_tag="BSU04040" downshifts 456794 /Source="Nicolas_upshifts" /id="D182" /incds=0 /nref=219 /ntot=253 /MaxReadThrough="3.23506" /MaxDrop="6.84998" /score="19.5535298" /energy="-11.7" /TU="NA" /idTUdmin="U314" /TUdmin="-21" /isTUend="TRUE" downshifts complement(456870) /Source="Nicolas_upshifts" /id="D183" /incds=0 /nref=1 /ntot=7 /MaxReadThrough="0.52326" /MaxDrop="2.84763" /score="25.9755124" /energy="-11.7" /TU="NA" /idTUdmin="U313" /TUdmin="-1079" /isTUend="FALSE" promotor_-35 456900..456906 /Source="Nicolas_upshift_promotors" /id="U315" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.386613386613387" /psig="0.996003996003996" /xcortree=2194 /SigmaFactorBS="attctgggaccatggtaggttttctgacaaaagtATTTCACa aactgatatgatTCACTTATAATGAAATAAAGttcaaaaattcggaatagtcgttccg a" /listShort="S134, ycsF, ycsG, ycsI, kipI, kipA, kipR, lipC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 456920..456939 /Source="Nicolas_upshift_promotors" /id="U315" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.386613386613387" /psig="0.996003996003996" /xcortree=2194 /SigmaFactorBS="attctgggaccatggtaggttttctgacaaaagtATTTCACa aactgatatgatTCACTTATAATGAAATAAAGttcaaaaattcggaatagtcgttccg a" /listShort="S134, ycsF, ycsG, ycsI, kipI, kipA, kipR, lipC" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 456926..457022 /Source="Nicolas_S_feature" /locus_tag="new_456926_457022" /HighExp="S1, Cold, S0, GM 5, BMM, MG 25, Lbtran, aero, GM 10, HiOs" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.996" /TUlongSig="NA" /TUlongPSig="NA" /label="S134" upshifts 456926 /Source="Nicolas_upshifts" /id="U315" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.386613386613387" /psig="0.996003996003996" /xcortree=2194 /SigmaFactorBS="attctgggaccatggtaggttttctgacaaaagtATTTCACa aactgatatgatTCACTTATAATGAAATAAAGttcaaaaattcggaatagtcgttccg a" /listShort="S134, ycsF, ycsG, ycsI, kipI, kipA, kipR, lipC" /GFF_Attribute="listLong" CDS 457023..457796 /gene="pxpA" /locus_tag="BSU_04050" /old_locus_tag="BSU04050" /EC_number="3.5.2.9" /function="16.6: Maintain" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:9334321, 28830929" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9334321, 28830929; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="oxoprolinase subunit A" /protein_id="NP_388287.3" /db_xref="EnsemblGenomes-Gn:BSU04050" /db_xref="EnsemblGenomes-Tr:CAB12213" /db_xref="GOA:P42963" /db_xref="InterPro:IPR005501" /db_xref="InterPro:IPR011330" /db_xref="SubtiList:BG11227" /db_xref="UniProtKB/Swiss-Prot:P42963" /translation="MFQIDLNCDLGESFGAYKIGLDQDILEYVTSANIACGFHAGDPS VMRKTVALAAERGVKMGAHPGLPDLLGFGRRNMAISPEEAYDLVVYQIGALSGFLKAE GLHMQHVKPHGALYNMAAVDQKLSDAIAKAVYKVDPGLILFGLAESELVKAGERIGLQ TANEVFADRTYQSDGTLTPRSQPDALIESDDAAVTQVIKMVKEGAVKSQQGHDVSLKA DTVCIHGDGAHALTFAQKIRKQLKAAGIEVTAISEQRST*" gene 457023..457796 /gene="pxpA" /locus_tag="BSU_04050" /old_locus_tag="BSU04050" CDS 457811..459025 /gene="pxpG" /locus_tag="BSU_04060" /old_locus_tag="BSU04060" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2b: Function from indirect experimental evidences (e.g. phenotypes); PubMedId: 9334321, 15849754, 16850406, 28830929; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="5-oxoproline transporter" /protein_id="NP_388288.3" /db_xref="EnsemblGenomes-Gn:BSU04060" /db_xref="EnsemblGenomes-Tr:CAB12214" /db_xref="GOA:P42964" /db_xref="InterPro:IPR001046" /db_xref="SubtiList:BG11228" /db_xref="UniProtKB/Swiss-Prot:P42964" /translation="MEQQKKTAGKKAGSWSLLMGAAFLMATSAIGPGFLTQTATFTNT LAASFGFVILISIILDIFAQTNVWRIIAVSGKRGQEIANMVLPGLGYFIAILVVLGGL AFNIGNIGGAGLGLQVLFGITPETGALISAVIAILIFVIKEAGKAMDRFTQIAGFVMI ILTVYVAATTAPPVGQAVANTFVPEHISIFAIVTLVGGTVGGYITFAGGHRLLDAGIK GKESIPQVTKSSVVGILITSVMRIALFLAVLGVVSKGLHIDESNPAASVFKLAAGNVG YKIFGLIMWSAAITSVIGAAYTSVSFFKTFSPKIEKNSRGIIIGFIVVSTLAFVTIGQ PAKILVLVGSLNGLILPIALGTLLVAAYKKNIVGDYKHPLWLTSTGALVVIVMAVMGI YTLCTQLPQLWS*" gene 457811..459025 /gene="pxpG" /locus_tag="BSU_04060" /old_locus_tag="BSU04060" CDS 459049..459822 /gene="pxpI" /locus_tag="BSU_04070" /old_locus_tag="BSU04070" /function="16.11: Scavenge (Catabolism)" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 8186229, 9334321, 28830929; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative D-5-oxoproline epimerase" /protein_id="NP_388289.3" /db_xref="EnsemblGenomes-Gn:BSU04070" /db_xref="EnsemblGenomes-Tr:CAB12215" /db_xref="GOA:P42966" /db_xref="InterPro:IPR009906" /db_xref="InterPro:IPR016938" /db_xref="SubtiList:BG11230" /db_xref="UniProtKB/Swiss-Prot:P42966" /translation="MAPKDVRALIREGKINGPTAGMSGGYAQANLVVLKKDLAFDFLL FCQRNQKPCPVLDVTEAGSPVPSLAAPDADIRTDFPKYRIYRHGILTEEVSDITPYWE DDFVGFLIGCSFSFEQALINNGIAVRHIDEGTNVSMYKTNIDCVPAGAFHGQMVVSMR PVPERLAVRAAQVTSRFPAVHGGPIHIGNPGAIGIRDLGKPDFGDAVSIRDGEVPVFW ACGVTPQAVAMNVKPEMVITHAPGHMLITDIRDESLAVL*" gene 459049..459822 /gene="pxpI" /locus_tag="BSU_04070" /old_locus_tag="BSU04070" CDS 459867..460589 /gene="pxpB" /locus_tag="BSU_04080" /old_locus_tag="BSU04080" /EC_number="3.5.2.9" /function="16.8: Protect" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:9334321, 18823995, 19040634, 20524093, 21050859, 21245531, 22277658, 28830929" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9334321, 18823995, 19040634, 20524093, 21050859, 21245531, 22277658, 28830929; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="L-5-oxoprolinase (ATP-dependent) subunit B" /protein_id="NP_388290.2" /db_xref="EnsemblGenomes-Gn:BSU04080" /db_xref="EnsemblGenomes-Tr:CAB12216" /db_xref="GOA:P60495" /db_xref="InterPro:IPR003833" /db_xref="InterPro:IPR010016" /db_xref="InterPro:IPR024946" /db_xref="InterPro:IPR029000" /db_xref="PDB:2KWA" /db_xref="PDB:2ZP2" /db_xref="SubtiList:BG11231" /db_xref="UniProtKB/Swiss-Prot:P60495" /translation="MTVRYQIEQLGDSAMMIRFGEEINEQVNGIVHAAAAYIEEQPFP GFIECIPAFTSLTVFYDMYEVYKHLPQGISSPFESVKRDVEERLAEIAEDYEVNRRIV EIPVCYGGEFGPDLEEVAKINQLSPEEVIDIHTNGEYVVYMLGFAPGFPFLGGMSKRI AAPRKSSPRPSIPAGSVGIAGLQTGVYPISTPGGWQLIGKTPLALFRPQENPPTLLRA GDIVKFVRISEKDYHAYKEESN*" gene 459867..460589 /gene="pxpB" /locus_tag="BSU_04080" /old_locus_tag="BSU04080" CDS 460592..461599 /gene="pxpC" /locus_tag="BSU_04090" /old_locus_tag="BSU04090" /EC_number="3.5.2.9" /function="16.6: Maintain" /function="16.8: Protect" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:9334321, 18823995, 19040634, 20524093, 21050859, 21245531, 22277658, 28830929" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9334321, 18823995, 19040634, 20524093, 21050859, 21245531, 22277658, 28830929; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="L-5-oxoprolinase (ATP-dependent) subunit C" /protein_id="YP_054571.2" /db_xref="EnsemblGenomes-Gn:BSU04090" /db_xref="EnsemblGenomes-Tr:CAE01447" /db_xref="GOA:Q7WY77" /db_xref="InterPro:IPR003778" /db_xref="InterPro:IPR029000" /db_xref="SubtiList:BG14193" /db_xref="UniProtKB/Swiss-Prot:Q7WY77" /translation="MKVLKPGLLTTVQDIGRTGYQKYGVLASGAMDTVSLRIANLLIG NGENEAGLEITMMGPGPSFHFSKQTLIAVTGADFTLRINDEEAPLWKPVLIKENSTVS FGPCKLGSRAYLAAAGGIEVPAVMESKSTYVRGSIGGLHGRALQKEDELNIGEMSALS QTILSRLSSQLGKQGFAAPKWSVSRGRFLPLKKNPVIRVLEGKQFAFFTEESKTRFYE EAFRVTPQSDRMGYRLKGEPLELKAPLEMVSEAVSFGTVQVPPDGNPIILLADRQTTG GYPRIAHIISADLPIVSQIMPGEHVQFEPVSLQEAEALAVEREQHIKELKTRMKMEWL T*" gene 460592..461599 /gene="pxpC" /locus_tag="BSU_04090" /old_locus_tag="BSU04090" downshifts 461085 /Source="Nicolas_upshifts" /id="D184" /incds=1 /nref=6 /ntot=27 /MaxReadThrough="5.04721" /MaxDrop="4.5277" /score="-7.2426149" /energy="-12.4" /TU="U315" /idTUdmin="U315" /TUdmin="-1975" /isTUend="FALSE" promotor_no_box 461179..461279 /Source="Nicolas_upshift_promotors" /id="U316" /multdbtbs="-" /comp="M21" /sig="Sig-" /pcomp="0.645354645354645" /psig="0.020979020979021" /xcortree=1726 /SigmaFactorBS="cattcgggtgctggaaggaaagcaatttgcctttttcacaga agaatcaaaaacgcgtttttatgaagaagcatttcgtgtcacgccgcagtccgaccgt a" /listShort="kipR, lipC" /GFF_Attribute="listLong" /label="promotor_no_box" upshifts 461239 /Source="Nicolas_upshifts" /id="U316" /multdbtbs="-" /comp="M21" /sig="Sig-" /pcomp="0.645354645354645" /psig="0.020979020979021" /xcortree=1726 /SigmaFactorBS="cattcgggtgctggaaggaaagcaatttgcctttttcacaga agaatcaaaaacgcgtttttatgaagaagcatttcgtgtcacgccgcagtccgaccgt a" /listShort="kipR, lipC" /GFF_Attribute="listLong" CDS 461615..462367 /gene="pxpR" /locus_tag="BSU_04100" /old_locus_tag="BSU04100" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 9334321; Product type r : regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator of the pxp operon (IclR family)" /protein_id="NP_388291.2" /db_xref="EnsemblGenomes-Gn:BSU04100" /db_xref="EnsemblGenomes-Tr:CAB12217" /db_xref="GOA:P42968" /db_xref="InterPro:IPR005471" /db_xref="InterPro:IPR014757" /db_xref="InterPro:IPR029016" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG11214" /db_xref="UniProtKB/Swiss-Prot:P42968" /translation="MQNKNKTVVKSMALLNLFLHKPSLTLSELVSLTGMPKTSVHRMV SSLEEMGFLSRDASGAYSLGLVFLEFGQLVADRLDIRKIAKPVMEELCREVDEAVQLI MRDGNEAIYVEKIEGTQTVRLYTAIGRRSPLYAGACARSILSFLPREEIEAYIKQTEL ISIGSGTITDPEKLLQEIDASVQNGYTVSYSELENYTAAIGAPIFNHERQVAAGISIA GFEARFTEDRLPYLTEKVKDAALQISRKIGYT*" gene 461615..462367 /gene="pxpR" /locus_tag="BSU_04100" /old_locus_tag="BSU04100" promotor_-35 462365..462374 /Source="Nicolas_upshift_promotors" /id="U317" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1275 /SigmaFactorBS="cagatttcaagaaaaataggatatacaTAAGTAGCCAatctt ttctctgcTGCGTACATTAACGTATCGAcgttcaagagtggaggaaagaacatggtgc t" /listShort="lipC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 462388..462407 /Source="Nicolas_upshift_promotors" /id="U317" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1275 /SigmaFactorBS="cagatttcaagaaaaataggatatacaTAAGTAGCCAatctt ttctctgcTGCGTACATTAACGTATCGAcgttcaagagtggaggaaagaacatggtgc t" /listShort="lipC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 462398 /Source="Nicolas_upshifts" /id="U317" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1275 /SigmaFactorBS="cagatttcaagaaaaataggatatacaTAAGTAGCCAatctt ttctctgcTGCGTACATTAACGTATCGAcgttcaagagtggaggaaagaacatggtgc t" /listShort="lipC" /GFF_Attribute="listLong" CDS 462431..463072 /gene="lipC" /locus_tag="BSU_04110" /old_locus_tag="BSU04110" /EC_number="3.1.1.-" /function="16.3: Control" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:9334321, 17220230, 20057119" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9334321, 17220230, 20057119; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="spore coat phospholipase B" /protein_id="NP_388292.1" /db_xref="EnsemblGenomes-Gn:BSU04110" /db_xref="EnsemblGenomes-Tr:CAB12218" /db_xref="GOA:P42969" /db_xref="InterPro:IPR013830" /db_xref="InterPro:IPR036514" /db_xref="SubtiList:BG11232" /db_xref="UniProtKB/Swiss-Prot:P42969" /translation="MVLRYTALGDSLTTGRGSGLFSPGFVQRFGDMMEADLKTRTAIN IFARSGLNTEEILGLLSYPYVQKCIRDADMITITGCGNDLIDSVLAYQTSKDETIFSR VSAHCHENFEKMIAKVAEIKGENPSPYAIRVFNLYNPFPEIDIAGKWITSFNSHLETL ASAPHVKIADAYSIFKGKEQEYLSFDGVHPNSKGYQAMAEAVHKLGYKELSVS*" gene 462431..463072 /gene="lipC" /locus_tag="BSU_04110" /old_locus_tag="BSU04110" downshifts 463058 /Source="Nicolas_upshifts" /id="D185" /incds=0 /nref=106 /ntot=223 /MaxReadThrough="0.550230000000001" /MaxDrop="6.63515" /score="26.7371783" /energy="-11.8" /TU="NA" /idTUdmin="U315" /TUdmin="-2" /isTUend="TRUE" S_feature complement(463070..463495) /Source="Nicolas_S_feature" /locus_tag="new_463070_463495_c" /HighExp="S1, Sw, BC, S2, Lbtran, M0t90, LPhT, BI, M40t45, C90" /AntisenseName="yczI" /AntisenseCor="-0.57558682544748696" /AntisenseRegPval="-24.4" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.965" /TUlongSig="NA" /TUlongPSig="NA" /label="S135" downshifts complement(463115) /Source="Nicolas_upshifts" /id="D186" /incds=0 /nref=171 /ntot=252 /MaxReadThrough="1.91715" /MaxDrop="5.13764" /score="6.4765859" /energy="-11.8" /TU="NA" /idTUdmin="U319" /TUdmin="-1" /isTUend="TRUE" promotor_-35 463148..463154 /Source="Nicolas_upshift_promotors" /id="U318" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.361638361638362" /psig="0.998001998001998" /xcortree=2779 /SigmaFactorBS="gatcgaaatattaaaagaaacttaaaattctctgtcttcTGT TCTAcagacaaacaaagTGCGCTAGAATAATGGAGGGcgtaggcaaatatagccataa c" /listShort="yczI, S136, pbpC, S137, ycsN" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 463168..463187 /Source="Nicolas_upshift_promotors" /id="U318" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.361638361638362" /psig="0.998001998001998" /xcortree=2779 /SigmaFactorBS="gatcgaaatattaaaagaaacttaaaattctctgtcttcTGT TCTAcagacaaacaaagTGCGCTAGAATAATGGAGGGcgtaggcaaatatagccataa c" /listShort="yczI, S136, pbpC, S137, ycsN" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 463169 /Source="Nicolas_upshifts" /id="U318" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.361638361638362" /psig="0.998001998001998" /xcortree=2779 /SigmaFactorBS="gatcgaaatattaaaagaaacttaaaattctctgtcttcTGT TCTAcagacaaacaaagTGCGCTAGAATAATGGAGGGcgtaggcaaatatagccataa c" /listShort="yczI, S136, pbpC, S137, ycsN" /GFF_Attribute="listLong" CDS 463245..463490 /gene="yczI" /locus_tag="BSU_04120" /old_locus_tag="BSU04120" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_388293.1" /db_xref="EnsemblGenomes-Gn:BSU04120" /db_xref="EnsemblGenomes-Tr:CAB12219" /db_xref="GOA:P42970" /db_xref="InterPro:IPR025018" /db_xref="SubtiList:BG12783" /db_xref="UniProtKB/Swiss-Prot:P42970" /translation="MFRIFKMSFAVIIIILALIAFNYTEHTSVIQSVMLVFLGAVMFM QGLEERKKENDGSGAFNIYTAVFVWSVSLIGFTLHII*" gene 463245..463490 /gene="yczI" /locus_tag="BSU_04120" /old_locus_tag="BSU04120" S_feature 463491..463901 /Source="Nicolas_S_feature" /locus_tag="new_463491_463901" /HighExp="T5.0H, T2.30H, T3.30H, T2.0H, T3.0H, T4.0H, T1.30H, M9-stat, T-4.40H, T-3.40H" /AntisenseName="yczJ" /AntisenseCor="-0.20847541933848601" /AntisenseRegPval="-3.2" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.998" /TUlongSig="NA" /TUlongPSig="NA" /label="S136" CDS complement(463496..463783) /gene="yczJ" /locus_tag="BSU_04130" /old_locus_tag="BSU04130" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_388294.1" /db_xref="EnsemblGenomes-Gn:BSU04130" /db_xref="EnsemblGenomes-Tr:CAB12220" /db_xref="InterPro:IPR007138" /db_xref="InterPro:IPR011008" /db_xref="SubtiList:BG12784" /db_xref="UniProtKB/Swiss-Prot:O31484" /translation="MVREAAMLHIKEGLEQEFEDAFRQAAPIISGMKGYITHSLSKCM EETHKYLLLVEWETLEDHTEGFRGSSEYQEWKALLHRFYTPFPTVEHFQDV*" gene complement(463496..463783) /gene="yczJ" /locus_tag="BSU_04130" /old_locus_tag="BSU04130" misc_feature complement(463804..463823) /Source="Nicolas_upshift_promotors" /id="U319" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.542457542457542" /psig="0.965034965034965" /xcortree=1595 /SigmaFactorBS="aagatttttttgaaaatgaaggaaaagttcaccgattttgca gaaatctcctatcgtTTGCTGTAGACTATTTGAAAagacagaaagaagggatagcatg g" /listShort="yczJ, S135" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(463820) /Source="Nicolas_upshifts" /id="U319" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.542457542457542" /psig="0.965034965034965" /xcortree=1595 /SigmaFactorBS="aagatttttttgaaaatgaaggaaaagttcaccgattttgca gaaatctcctatcgtTTGCTGTAGACTATTTGAAAagacagaaagaagggatagcatg g" /listShort="yczJ, S135" /GFF_Attribute="listLong" promotor_-35 463877..463881 /Source="Nicolas_upshift_promotors" /id="U320" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.855144855144855" /psig="0.946053946053946" /xcortree=2681 /SigmaFactorBS="aaatcggtgaacttttccttcattttcaaaaaaaTCTTGcac gcaccaattcaatTAAGAGAAAATAACAAGTGGaaggcaggggaaagtcatgttaaaa a" /listShort="pbpC, S137, ycsN, S138, mtlR" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 463898..463917 /Source="Nicolas_upshift_promotors" /id="U320" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.855144855144855" /psig="0.946053946053946" /xcortree=2681 /SigmaFactorBS="aaatcggtgaacttttccttcattttcaaaaaaaTCTTGcac gcaccaattcaatTAAGAGAAAATAACAAGTGGaaggcaggggaaagtcatgttaaaa a" /listShort="pbpC, S137, ycsN, S138, mtlR" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 463903 /Source="Nicolas_upshifts" /id="U320" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.855144855144855" /psig="0.946053946053946" /xcortree=2681 /SigmaFactorBS="aaatcggtgaacttttccttcattttcaaaaaaaTCTTGcac gcaccaattcaatTAAGAGAAAATAACAAGTGGaaggcaggggaaagtcatgttaaaa a" /listShort="pbpC, S137, ycsN, S138, mtlR" /GFF_Attribute="listLong" CDS 463934..465940 /gene="pbpC" /locus_tag="BSU_04140" /old_locus_tag="BSU04140" /function="16.13: Shape" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:8830698, 10648534" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8830698, 10648534; Product type lp: lipoprotein" /codon_start=1 /transl_table=11 /product="penicillin-binding lipoprotein 3; transpeptidase" /protein_id="NP_388295.1" /db_xref="EnsemblGenomes-Gn:BSU04140" /db_xref="EnsemblGenomes-Tr:CAB12221" /db_xref="GOA:P42971" /db_xref="InterPro:IPR001460" /db_xref="InterPro:IPR005311" /db_xref="InterPro:IPR007887" /db_xref="InterPro:IPR012338" /db_xref="InterPro:IPR032710" /db_xref="InterPro:IPR036138" /db_xref="SubtiList:BG11234" /db_xref="UniProtKB/Swiss-Prot:P42971" /translation="MLKKCILLVFLCVGLIGLIGCSKTDSPEDRMEAFVKQWNDQQFD DMYQSLTKDVKKEISKKDFVNRYKAIYEQAGVKNLKVTAGEVDKDDQDNKTMKHIPYK VSMNTNAGKVSFKNTAVLKLEKTDDEESWNIDWDPSFIFKQLADDKTVQIMSIEPKRG QIYDKNGKGLAVNTDVPEIGIVPGELGDKKEKVIKELAKKLDLTEDDIKKKLDQGWVK DDSFVPLKKVKPDQEKLVSEATSLQGVTRTNVSSRYYPYGEKTAHLTGYVRAITAEEL KKKKEGTYSDTSNIGIAGLENVYEDKLRGTTGWKIYVPQTGEVIAEKKAKDGEDLHLT IDIKTQMKLYDELKDDSGAAVALQPKTGETLALVSAPSYDPNGFIFGWSDKEWKKLNK DKNNPFSAKFNKTYAPGSTIKPIAAAIGIKNGTLKADEKKTIKGKEWQKDSSWGGYSV TRVSERLQQVDLENALITSDNIYFAQNALDMGADTFTKGLKTFGFSEDVPYEFPIQKS SIANDKLDSDILLADTGYGQGQMQMSPLHLATAYTPFVDNGDLVKPTLIKKDSQTADV WHKQVVTKEGAADITKGLKGVVEDERGSAYQPVVKGITVAGKTGTAELKTSKDDKDGT ENGWFVGYDYENKDLLVAMMIQNVQDRGGSHYVVEKAKKQFQSN*" gene 463934..465940 /gene="pbpC" /locus_tag="BSU_04140" /old_locus_tag="BSU04140" S_feature 465941..466041 /Source="Nicolas_S_feature" /locus_tag="new_465941_466041" /HighExp="LBGstat, T5.0H, M0t45, T3.30H, S0, LBGtran, Oxctl, T4.0H, C30, T3.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="0.946, 0.998" /TUlongSig="NA" /TUlongPSig="NA" /label="S137" CDS 466042..466944 /gene="ycsN" /locus_tag="BSU_04150" /old_locus_tag="BSU04150" /EC_number="1.1.1.-" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 22720735; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative oxidoreductase" /protein_id="NP_388296.1" /db_xref="EnsemblGenomes-Gn:BSU04150" /db_xref="EnsemblGenomes-Tr:CAB12222" /db_xref="GOA:P42972" /db_xref="InterPro:IPR020471" /db_xref="InterPro:IPR023210" /db_xref="InterPro:IPR036812" /db_xref="SubtiList:BG11235" /db_xref="UniProtKB/Swiss-Prot:P42972" /translation="MQRIQLAEDLQFSRVIHGLWRLNEWNYSDAELLSLIEWCIDHGI TTFDHADIYGGYTCEKLFGNALALSPGLRENIELVTKCGIVLESPERPAHRSHHYNTS KSHILASVEQSLMNLRTDYIDMLLIHRPDPLMDPEGVAEAFQALKCSGKVRYFGVSNF KDHQYRMLESYLPEKLVTNQIELSAYELENMLDGTLNLCQEKRIPPMAWSPLAGGKVF TENTDKDRRVRTALESVQGEIGAASLDEVMYAWLYTHPAGIMPIVGSGKRERISAAIN ALSYKLDQDQWFRIFTAVQGYDIP*" gene 466042..466944 /gene="ycsN" /locus_tag="BSU_04150" /old_locus_tag="BSU04150" downshifts 466924 /Source="Nicolas_upshifts" /id="D187" /incds=0 /nref=48 /ntot=206 /MaxReadThrough="3.20352" /MaxDrop="4.57855" /score="1.36962171" /energy="-10.6" /TU="U320" /idTUdmin="U318" /TUdmin="-8" /isTUend="TRUE" promotor_-35 467017..467024 /Source="Nicolas_upshift_promotors" /id="U321" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.779220779220779" /psig="0.995004995004995" /xcortree=1547 /SigmaFactorBS="gtcacaccgcttagtgccaaattaccatttataagTGATTGA TtctttcttgaaagCGTTTTATATTAAAAGGAAAcctctctatatcctctactgcatc t" /listShort="S138, mtlR" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 467038..467057 /Source="Nicolas_upshift_promotors" /id="U321" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.779220779220779" /psig="0.995004995004995" /xcortree=1547 /SigmaFactorBS="gtcacaccgcttagtgccaaattaccatttataagTGATTGA TtctttcttgaaagCGTTTTATATTAAAAGGAAAcctctctatatcctctactgcatc t" /listShort="S138, mtlR" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 467042..467129 /Source="Nicolas_S_feature" /locus_tag="new_467042_467129" /HighExp="S0, Gly, BC, Lbstat, S2, M9-stat, G135, dia5, T0.30H, T2.30H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="0.995, 0.946" /TUlongSig="NA" /TUlongPSig="NA" /label="S138" upshifts 467042 /Source="Nicolas_upshifts" /id="U321" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.779220779220779" /psig="0.995004995004995" /xcortree=1547 /SigmaFactorBS="gtcacaccgcttagtgccaaattaccatttataagTGATTGA TtctttcttgaaagCGTTTTATATTAAAAGGAAAcctctctatatcctctactgcatc t" /listShort="S138, mtlR" /GFF_Attribute="listLong" CDS 467130..469214 /gene="mtlR" /locus_tag="BSU_04160" /old_locus_tag="BSU04160" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:12897001, 23279188, 24196428, 26159071" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12897001, 23279188, 24196428, 26159071; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator, PTS-dependent activator" /protein_id="NP_388297.1" /db_xref="EnsemblGenomes-Gn:BSU04160" /db_xref="EnsemblGenomes-Tr:CAB12223" /db_xref="GOA:P96574" /db_xref="InterPro:IPR002178" /db_xref="InterPro:IPR003501" /db_xref="InterPro:IPR007737" /db_xref="InterPro:IPR011608" /db_xref="InterPro:IPR013011" /db_xref="InterPro:IPR013196" /db_xref="InterPro:IPR016152" /db_xref="InterPro:IPR036095" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="InterPro:IPR036634" /db_xref="SubtiList:BG12049" /db_xref="UniProtKB/Swiss-Prot:P96574" /translation="MYMTAREQKLLKHLLLQNRYITVTELAELMQVSTRTIHRELKSI KPLMETVGLTLDKQPGKGLKAVGSPEGKQKLLTDLSYEQHEYSADERKLLILCSLLES QEPVKLYTLAHDLQVTNATVSYDLDELEKWISPFGLTLIRKRGFGIQLIGPENAKRKI VGNLIVNRLDIQMFLEAVELNIKGKTDSSEKMFGVVSKGELLKMERILFQLKEKIAFS LSDSSYIALVVHLTYAIERIKLGETITMEQNELEELMNAKEYSSALEIAGELERAFGV TIPEAEVGYITIHLRSANRKYKTEYKAQEIELETALQTKRLIAFISDKIRMDLTKNYS LYEGLIAHLEPAVSRIKENIEIYNPMKEQIKRDYFLLYMAIEEGVEKYFPGMSFSDDE IAFIVLHFGSALEIKKEEAKVKALVVCSSGIGSSKMLASRLKKELPEIESFDMSSLIE LKGKDVQAYDMIVSTVPIPYENIDYIMVSPLLNEEDANQVKQYIKRKIPLILNKKRSS KEEAQQADVPDMLEAAESIGRYMEVIQDVLRHFTLAQLKTNPDHSMLLLELFQQLKKD GLIRDPEKAAVCLAEREKQGGLGIPGTNMALYHLKNDEIVLPFFKMFDLSTPYEVDGM DGNTLRMTRILVMMAPGSLSAEGSEILSAISSAIIESGESMAGFQEEGGQELYQRLNR IFFTWMKEKNIL*" gene 467130..469214 /gene="mtlR" /locus_tag="BSU_04160" /old_locus_tag="BSU04160" downshifts 469201 /Source="Nicolas_upshifts" /id="D188" /incds=0 /nref=107 /ntot=220 /MaxReadThrough="1.91059" /MaxDrop="5.63565" /score="9.4904968" /energy="-12.4" /TU="NA" /idTUdmin="U321" /TUdmin="-19" /isTUend="TRUE" promotor_-35 469243..469249 /Source="Nicolas_upshift_promotors" /id="U322" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=739 /SigmaFactorBS="acctgcatggcacacgtcaaaaatttggCGTGTGTttttctg tggatgGGGAACAAAATAAGAAAATgtgggactattttatcattcagtattggaataa t" /listShort="S139, ydaB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 469263..469281 /Source="Nicolas_upshift_promotors" /id="U322" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=739 /SigmaFactorBS="acctgcatggcacacgtcaaaaatttggCGTGTGTttttctg tggatgGGGAACAAAATAAGAAAATgtgggactattttatcattcagtattggaataa t" /listShort="S139, ydaB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 469275 /Source="Nicolas_upshifts" /id="U322" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=739 /SigmaFactorBS="acctgcatggcacacgtcaaaaatttggCGTGTGTttttctg tggatgGGGAACAAAATAAGAAAATgtgggactattttatcattcagtattggaataa t" /listShort="S139, ydaB" /GFF_Attribute="listLong" S_feature 469286..469367 /Source="Nicolas_S_feature" /locus_tag="new_469286_469367" /HighExp="Etha, S5, S6, ferm, S8, nit, S7, BT, Salt, Sw" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigB" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S139" promotor_-35 469329..469336 /Source="Nicolas_upshift_promotors" /id="U323" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.69030969030969" /psig="0.992007992007992" /xcortree=1439 /SigmaFactorBS="gaataattccaaaatgaaatAGTTTTACaagttatctttttT GGGTTAAAATGGGTGAGGTaaggaagaaaatctaacaaattattgaagattcaagaga a" /listShort="ydaB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 469350..469369 /Source="Nicolas_upshift_promotors" /id="U323" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.69030969030969" /psig="0.992007992007992" /xcortree=1439 /SigmaFactorBS="gaataattccaaaatgaaatAGTTTTACaagttatctttttT GGGTTAAAATGGGTGAGGTaaggaagaaaatctaacaaattattgaagattcaagaga a" /listShort="ydaB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 469369 /Source="Nicolas_upshifts" /id="U323" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.69030969030969" /psig="0.992007992007992" /xcortree=1439 /SigmaFactorBS="gaataattccaaaatgaaatAGTTTTACaagttatctttttT GGGTTAAAATGGGTGAGGTaaggaagaaaatctaacaaattattgaagattcaagaga a" /listShort="ydaB" /GFF_Attribute="listLong" CDS 469426..470937 /gene="ydaB" /locus_tag="BSU_04170" /old_locus_tag="BSU04170" /EC_number="6.2.1.-" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative acyl-CoA ligase" /protein_id="NP_388298.2" /db_xref="EnsemblGenomes-Gn:BSU04170" /db_xref="EnsemblGenomes-Tr:CAB12224" /db_xref="GOA:P96575" /db_xref="InterPro:IPR000873" /db_xref="InterPro:IPR020845" /db_xref="InterPro:IPR025110" /db_xref="SubtiList:BG12050" /db_xref="UniProtKB/Swiss-Prot:P96575" /translation="METLQHLILHDMPNSEEIEAVKSGDHTLTYKGYRKRINQLANAM LQKGIQKGDRVALLCKNGHPASTVMFAALEIGAVVVPVSWQLKPYEMTGILKASEPKA MFYGAEFKEILDEVLPELSSLCVTMETGTAYETSAEFEALFAGPDHLPETEMVSPDDT ALLMFTSGTTGNPKRCMITHGGIYRYVKKSNSSIARMKGLRFLACHPIYHTSALICIM LGTFAETTFVFTKDQDPVHMLKVIEEEKIQTVMALPVFYTYLLEAWEKHQTDLSSLVI LMTGGTKVPSSLISRYLDIGIPLAHGYGSTEAWGISTWTPDMGMDKAASAGKPVAGVK VKVEDPLTGEELPQGEIGEIVVHTPFLFKGYEDNPEATAKVLQNGWFRTGDSGYVDED GFIFITGRYKDVIIYGGDNVYPDQVEEVIQQIPGILETAVVGIPDPLYGEKPKAFIVK NGGQRITEEDVIAFCKERLSAYKIPEVEFVNELPKNNLGKVKKDVLRNQAVHS*" gene 469426..470937 /gene="ydaB" /locus_tag="BSU_04170" /old_locus_tag="BSU04170" downshifts 470921 /Source="Nicolas_upshifts" /id="D189" /incds=0 /nref=3 /ntot=55 /MaxReadThrough="0.57376" /MaxDrop="3.70168" /score="9.4904968" /energy="-12.4" /TU="NA" /idTUdmin="U323" /TUdmin=73 /isTUend="FALSE" CDS complement(470957..471502) /gene="ydaC" /locus_tag="BSU_04180" /old_locus_tag="BSU04180" /EC_number="2.1.1.-" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative methyltransferase" /protein_id="NP_388299.1" /db_xref="EnsemblGenomes-Gn:BSU04180" /db_xref="EnsemblGenomes-Tr:CAB12225" /db_xref="GOA:P96576" /db_xref="InterPro:IPR029063" /db_xref="SubtiList:BG12051" /db_xref="UniProtKB/Swiss-Prot:P96576" /translation="MIAGYIMAAENQTLNQWTINQLGITRGDSILEVGFGPGYCMQQM LKREKDVHLHGIDVSEAMLKLAARRVKPKGVRLIQGSIETFPLPASFYDKVISVNNYT IWNDQTKGIKQIYRALKPGGKAAITMQPREADASPEKTKSFGRQMIADFKAAGFEDID IQFKNIKPELSVCATAKKPAT*" gene complement(470957..471502) /gene="ydaC" /locus_tag="BSU_04180" /old_locus_tag="BSU04180" downshifts complement(470990) /Source="Nicolas_upshifts" /id="D190" /incds=0 /nref=3 /ntot=11 /MaxReadThrough="1.44039" /MaxDrop="3.73662" /score="-9.35066962" /energy="-11.5" /TU="NA" /idTUdmin="U324" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(471569..471587) /Source="Nicolas_upshift_promotors" /id="U324" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=211 /SigmaFactorBS="tggcttggcaccttcgcattgctttatcagaaaaaTGTTTCA catggaacgctgagAGGAAATTAACTCAAAAAGggggttggttgctgaatgattaaca t" /listShort="ydaC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(471583) /Source="Nicolas_upshifts" /id="U324" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=211 /SigmaFactorBS="tggcttggcaccttcgcattgctttatcagaaaaaTGTTTCA catggaacgctgagAGGAAATTAACTCAAAAAGggggttggttgctgaatgattaaca t" /listShort="ydaC" /GFF_Attribute="listLong" promotor_-35 complement(471602..471608) /Source="Nicolas_upshift_promotors" /id="U324" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=211 /SigmaFactorBS="tggcttggcaccttcgcattgctttatcagaaaaaTGTTTCA catggaacgctgagAGGAAATTAACTCAAAAAGggggttggttgctgaatgattaaca t" /listShort="ydaC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 471644..471650 /Source="Nicolas_upshift_promotors" /id="U325" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=191 /SigmaFactorBS="tgaaacatttttctgataaagcaatgcgaaggtgccaagcca TGTTTATccaaagagtgtgtgAGGTACACAACAAATAGACatgaaaacaaaggaggag a" /listShort="ydaD, ydaE, ydaF" /listLong="ydaG, S140" /label="promotor_-35" upshifts 471662 /Source="Nicolas_upshifts" /id="U325" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=191 /SigmaFactorBS="tgaaacatttttctgataaagcaatgcgaaggtgccaagcca TGTTTATccaaagagtgtgtgAGGTACACAACAAATAGACatgaaaacaaaggaggag a" /listShort="ydaD, ydaE, ydaF" /listLong="ydaG, S140" promotor_-10 471665..471683 /Source="Nicolas_upshift_promotors" /id="U325" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=191 /SigmaFactorBS="tgaaacatttttctgataaagcaatgcgaaggtgccaagcca TGTTTATccaaagagtgtgtgAGGTACACAACAAATAGACatgaaaacaaaggaggag a" /listShort="ydaD, ydaE, ydaF" /listLong="ydaG, S140" /label="promotor_-10" CDS 471709..472569 /gene="ydaD" /locus_tag="BSU_04190" /old_locus_tag="BSU04190" /EC_number="1.1.1.-" /function="16.11: Scavenge (Catabolism)" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 10220166, 11948145, 15805528, 21520290, 28197687; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative dehydrogenase" /protein_id="NP_388300.1" /db_xref="EnsemblGenomes-Gn:BSU04190" /db_xref="EnsemblGenomes-Tr:CAB12226" /db_xref="GOA:P80873" /db_xref="InterPro:IPR002347" /db_xref="InterPro:IPR020904" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG12052" /db_xref="UniProtKB/Swiss-Prot:P80873" /translation="MANYPKELPAQTQSRQPGIESEMNPSPVYEYEDYKGADKLKGKV ALITGGDSGIGRAVSVAYAKEGADIAIVYKDEHEDAEETKKRVEQEGVKCLLIAGDVG EEEFCNEAVEKTVKELGGLDILVNNAGEQHPKESIKDITSEQLHRTFKTNFYSQFYLT KKAIDYLKPGSAIINTTSINPYVGNPTLIDYTATKGAINAFTRTMAQALVKDGIRVNA VAPGPIWTPLIPATFPEETVAQFGQDTPMGRPGQPVEHVGCYVLLASDESSYMTGQTL HVNGGNFVTT*" gene 471709..472569 /gene="ydaD" /locus_tag="BSU_04190" /old_locus_tag="BSU04190" CDS 472585..473088 /gene="lyxE" /locus_tag="BSU_04200" /old_locus_tag="BSU04200" /EC_number="5.3.1.15" /experiment="publication(s) with functional evidences, PMID:10220166, 15805528, 21421786, 21520290" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10220166, 15805528, 21421786, 21520290; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="D-lyxose ketol isomerase" /protein_id="NP_388301.1" /db_xref="EnsemblGenomes-Gn:BSU04200" /db_xref="EnsemblGenomes-Tr:CAB12227" /db_xref="GOA:P96578" /db_xref="InterPro:IPR011051" /db_xref="InterPro:IPR014710" /db_xref="PDB:2Y0O" /db_xref="SubtiList:BG12053" /db_xref="UniProtKB/Swiss-Prot:P96578" /translation="MGITKEEVNSYYQKAGIVLTDEEVDQIQLMDYGLGKERKVGLQL FVYVNTDRYCSKELVLFPGQTCPEHRHPPVDGQEGKQETFRCRYGKVYLYVEGEKTPL PKVLPPQEDREHYTVWHEIELEPGGQYTIPPNTKHWFQAGEEGAVVTEMSSTSTDKHD IFTDPRI*" gene 472585..473088 /gene="lyxE" /locus_tag="BSU_04200" /old_locus_tag="BSU04200" downshifts 473069 /Source="Nicolas_upshifts" /id="D191" /incds=0 /nref=16 /ntot=26 /MaxReadThrough="4.81615" /MaxDrop="6.21035" /score="29.8440619" /energy="-15.5" /TU="U325" /idTUdmin="U325" /TUdmin="-683" /isTUend="FALSE" promotor_-35 473117..473124 /Source="Nicolas_upshift_promotors" /id="U326" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.95004995004995" /psig=1 /xcortree=2929 /SigmaFactorBS="agaatataaggatgggcttaacagcccatcctttttgTATTG AAAaaaacagaatcatCGCTATAATGGGTAAAAAAGgaaagagggcgaggcaatgttc a" /listShort="ydaF, ydaG, S140" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 473138..473157 /Source="Nicolas_upshift_promotors" /id="U326" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.95004995004995" /psig=1 /xcortree=2929 /SigmaFactorBS="agaatataaggatgggcttaacagcccatcctttttgTATTG AAAaaaacagaatcatCGCTATAATGGGTAAAAAAGgaaagagggcgaggcaatgttc a" /listShort="ydaF, ydaG, S140" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 473140 /Source="Nicolas_upshifts" /id="U326" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.95004995004995" /psig=1 /xcortree=2929 /SigmaFactorBS="agaatataaggatgggcttaacagcccatcctttttgTATTG AAAaaaacagaatcatCGCTATAATGGGTAAAAAAGgaaagagggcgaggcaatgttc a" /listShort="ydaF, ydaG, S140" /GFF_Attribute="listLong" CDS 473174..473725 /gene="ydaF" /locus_tag="BSU_04210" /old_locus_tag="BSU04210" /EC_number="2.3.1.-" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15468321; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative ribosomal protein N-acetyltransferase" /protein_id="NP_388302.1" /db_xref="EnsemblGenomes-Gn:BSU04210" /db_xref="EnsemblGenomes-Tr:CAB12228" /db_xref="GOA:P96579" /db_xref="InterPro:IPR000182" /db_xref="InterPro:IPR016181" /db_xref="PDB:1NSL" /db_xref="SubtiList:BG12054" /db_xref="UniProtKB/Swiss-Prot:P96579" /translation="MFTCKVNEHITIRLLEPKDAERLAELIIQNQQRLGKWLFFAENP SSADTYRETIIPDWRRQYADLNGIEAGLLYDGSLCGMISLHNLDQVNRKAEIGYWIAK EFEGKGIITAACRKLITYAFEELELNRVAICAAVGNEKSRAVPERIGFLEEGKARDGL YVNGMHHDLVYYSLLKREWEGEK*" gene 473174..473725 /gene="ydaF" /locus_tag="BSU_04210" /old_locus_tag="BSU04210" promotor_-35 473740..473746 /Source="Nicolas_upshift_promotors" /id="U327" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=268 /SigmaFactorBS="ggcgaaaaataaagagcacactttctTGTTTAAatcttcccc ggatgTGGAAAAGTAACAGCGGAGacgttaaaaaggagtgattcgagatgaatcagca a" /listShort="ydaG, S140" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 473761..473779 /Source="Nicolas_upshift_promotors" /id="U327" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=268 /SigmaFactorBS="ggcgaaaaataaagagcacactttctTGTTTAAatcttcccc ggatgTGGAAAAGTAACAGCGGAGacgttaaaaaggagtgattcgagatgaatcagca a" /listShort="ydaG, S140" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 473774 /Source="Nicolas_upshifts" /id="U327" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=268 /SigmaFactorBS="ggcgaaaaataaagagcacactttctTGTTTAAatcttcccc ggatgTGGAAAAGTAACAGCGGAGacgttaaaaaggagtgattcgagatgaatcagca a" /listShort="ydaG, S140" /GFF_Attribute="listLong" CDS 473803..474225 /gene="ydaG" /locus_tag="BSU_04220" /old_locus_tag="BSU04220" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 10220166; Product type f: factor" /codon_start=1 /transl_table=11 /product="putative general stress protein" /protein_id="NP_388303.1" /db_xref="EnsemblGenomes-Gn:BSU04220" /db_xref="EnsemblGenomes-Tr:CAB12229" /db_xref="GOA:P80238" /db_xref="InterPro:IPR012349" /db_xref="SubtiList:BG19017" /db_xref="UniProtKB/Swiss-Prot:P80238" /translation="MNQQDIKQKVLDVLDHHKVGSLATVQKGKPHSRYMTFFHDGLTI YTPTSKETHKAEEIENNPNVHILLGYDCEGFGDAYVEVAGKAKINNSAELKDKIWSSK LERWFDGKDDPNLVILEIEPEDIRLMNAGEKTPVSLEL*" gene 473803..474225 /gene="ydaG" /locus_tag="BSU_04220" /old_locus_tag="BSU04220" promotor_-35 474230..474238 /Source="Nicolas_upshift_promotors" /id="U328" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.753246753246753" /psig="0.993006993006993" /xcortree=273 /SigmaFactorBS="gtctcactcgaactataaaaaaTTTGTGTTTtcaggggcgaT ATGTTATTATGAATAGCTAgtaagaaaaataagcaaataaaaaagaaagtaaacttct t" /listShort="S140" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 474249..474268 /Source="Nicolas_upshift_promotors" /id="U328" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.753246753246753" /psig="0.993006993006993" /xcortree=273 /SigmaFactorBS="gtctcactcgaactataaaaaaTTTGTGTTTtcaggggcgaT ATGTTATTATGAATAGCTAgtaagaaaaataagcaaataaaaaagaaagtaaacttct t" /listShort="S140" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 474268..474634 /Source="Nicolas_S_feature" /locus_tag="new_474268_474634" /HighExp="Etha, Salt, Cold, Sw, B60, Gly, M9-stat, LPhT, B36, G135" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigB, SigA" /TUshortPSig="0.993, 0.999, 1" /TUlongSig="SigB" /TUlongPSig=1 /label="S140" upshifts 474268 /Source="Nicolas_upshifts" /id="U328" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.753246753246753" /psig="0.993006993006993" /xcortree=273 /SigmaFactorBS="gtctcactcgaactataaaaaaTTTGTGTTTtcaggggcgaT ATGTTATTATGAATAGCTAgtaagaaaaataagcaaataaaaaagaaagtaaacttct t" /listShort="S140" /GFF_Attribute="listLong" promotor_no_box complement(474294..474394) /Source="Nicolas_upshift_promotors" /id="U329" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.725274725274725" /psig="0.010989010989011" /xcortree=121 /SigmaFactorBS="aggggcgatttgttatgaaggaaaagaataagggcagctggt tatgctgcttgggaagcggtaagcttctctctcaaaacagaaaaaagaagtttacttt c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_no_box" misc_RNA complement(474329..474597) /gene="bsrC" /locus_tag="BSU_misc_RNA_64" /product="small regulatory RNA" /experiment="publication(s) with functional evidences, PMID:18948176, 23457461" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 18948176, 23457461; Product type n: RNA" gene complement(474329..474597) /gene="bsrC" /locus_tag="BSU_misc_RNA_64" upshifts complement(474334) /Source="Nicolas_upshifts" /id="U329" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.725274725274725" /psig="0.010989010989011" /xcortree=121 /SigmaFactorBS="aggggcgatttgttatgaaggaaaagaataagggcagctggt tatgctgcttgggaagcggtaagcttctctctcaaaacagaaaaaagaagtttacttt c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" downshifts 474591 /Source="Nicolas_upshifts" /id="D192" /incds=0 /nref=124 /ntot=275 /MaxReadThrough="2.67264" /MaxDrop="7.35087" /score="29.9942993" /energy="-12" /TU="NA" /idTUdmin="U326" /TUdmin=3 /isTUend="TRUE" promotor_-35 474671..474680 /Source="Nicolas_upshift_promotors" /id="U330" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1651 /SigmaFactorBS="gacggtttttttattgcaaaaaacacatcgtacTGAAACCTC CttgtcttctttcCAGTCTTATCTCTAGGatgaaattggaggaagaataacgtgcatg t" /listShort="ydaH, lrpC, topB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 474693..474708 /Source="Nicolas_upshift_promotors" /id="U330" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1651 /SigmaFactorBS="gacggtttttttattgcaaaaaacacatcgtacTGAAACCTC CttgtcttctttcCAGTCTTATCTCTAGGatgaaattggaggaagaataacgtgcatg t" /listShort="ydaH, lrpC, topB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 474698 /Source="Nicolas_upshifts" /id="U330" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1651 /SigmaFactorBS="gacggtttttttattgcaaaaaacacatcgtacTGAAACCTC CttgtcttctttcCAGTCTTATCTCTAGGatgaaattggaggaagaataacgtgcatg t" /listShort="ydaH, lrpC, topB" /GFF_Attribute="listLong" CDS 474731..475540 /gene="amj" /locus_tag="BSU_04230" /old_locus_tag="BSU04230" /experiment="publication(s) with functional evidences, PMID:15849754, 16850406, 25918422, 27537185" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15849754, 16850406, 25918422, 27537185; Product type t: transporter" /codon_start=1 /transl_table=11 /product="lipid II flippase" /protein_id="NP_388304.1" /db_xref="EnsemblGenomes-Gn:BSU04230" /db_xref="EnsemblGenomes-Tr:CAB12230" /db_xref="GOA:P96581" /db_xref="InterPro:IPR021260" /db_xref="SubtiList:BG12055" /db_xref="UniProtKB/Swiss-Prot:P96581" /translation="MHVITTQVLFIFCFLLLIHSIETLAYATRLSGARVGFIASALSL FNVMVIVSRMSNMVQQPFTGHLIDDAGKNALAIVGEQFRFLIFGSTVGTILGIILLPS FVALFSRAIIHLAGGGGSVFQVFRKGFSKQGFKNALSYLRLPSISYVKGFHMRLIPKR LFVINMLITSIYTIGVLSALYAGLLAPERSTTAVMASGLINGIATMLLAIFVDPKVSV LADDVAKGKRSYIYLKWTSVTMVTSRVAGTLLAQLMFIPGAYYIAWLTKWF*" gene 474731..475540 /gene="amj" /locus_tag="BSU_04230" /old_locus_tag="BSU04230" downshifts 475521 /Source="Nicolas_upshifts" /id="D193" /incds=0 /nref=5 /ntot=103 /MaxReadThrough="2.92236" /MaxDrop="3.54247" /score="15.7032536" /energy="-14.9" /TU="U330" /idTUdmin="U327" /TUdmin=911 /isTUend="FALSE" CDS complement(475584..475874) /gene="ydzA" /locus_tag="BSU_04240" /old_locus_tag="BSU04240" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_388305.1" /db_xref="EnsemblGenomes-Gn:BSU04240" /db_xref="EnsemblGenomes-Tr:CAB12231" /db_xref="GOA:O31485" /db_xref="InterPro:IPR023845" /db_xref="SubtiList:BG12807" /db_xref="UniProtKB/Swiss-Prot:O31485" /translation="MLHTPIGRLRTMGFIEGMSLLILLFIAMPLKYWAGLPLAVTIVG SVHGGLFILYLLVLAYATFSVKWPLKWSAAGFIAAFVPFGNFLYDRGLRNYK*" gene complement(475584..475874) /gene="ydzA" /locus_tag="BSU_04240" /old_locus_tag="BSU04240" downshifts complement(475588) /Source="Nicolas_upshifts" /id="D194" /incds=0 /nref=235 /ntot=260 /MaxReadThrough="1.23465" /MaxDrop="7.74945" /score="10.1798531" /energy="-14.9" /TU="NA" /idTUdmin="U332" /TUdmin=0 /isTUend="TRUE" misc_feature complement(475902..475921) /Source="Nicolas_upshift_promotors" /id="U332" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.653346653346653" /psig="0.967032967032967" /xcortree=1622 /SigmaFactorBS="catgtaaaaatgaatgttttccgaacattttttgaaagctgt catatgcccccccggATTGTTTATAGTATAAAATGaaaacgtgtccacaaggagggcg a" /listShort="ydzA" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" misc_feature 475902..475920 /Source="Nicolas_upshift_promotors" /id="U331" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.343656343656344" /psig="0.691308691308691" /xcortree=306 /SigmaFactorBS="aagtcttccgatcggcgtgtgcagcataaatcgccctccttg tggacacgttttCATTTTATACTATAAACAAtccgggggggcatatgacagctttcaa a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 475908 /Source="Nicolas_upshifts" /id="U331" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.343656343656344" /psig="0.691308691308691" /xcortree=306 /SigmaFactorBS="aagtcttccgatcggcgtgtgcagcataaatcgccctccttg tggacacgttttCATTTTATACTATAAACAAtccgggggggcatatgacagctttcaa a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" upshifts complement(475918) /Source="Nicolas_upshifts" /id="U332" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.653346653346653" /psig="0.967032967032967" /xcortree=1622 /SigmaFactorBS="catgtaaaaatgaatgttttccgaacattttttgaaagctgt catatgcccccccggATTGTTTATAGTATAAAATGaaaacgtgtccacaaggagggcg a" /listShort="ydzA" /GFF_Attribute="listLong" promotor_-35 475996..476003 /Source="Nicolas_upshift_promotors" /id="U333" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.765234765234765" /psig="0.999000999001" /xcortree=2269 /SigmaFactorBS="aacattcatttttacatgccttttctagggaactgTACTTGT CatttacaaaaataCCCGAGATAATGTGTACAAAatcaaaaaagaaggatgttgaaat g" /listShort="lrpC, topB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 476017..476036 /Source="Nicolas_upshift_promotors" /id="U333" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.765234765234765" /psig="0.999000999001" /xcortree=2269 /SigmaFactorBS="aacattcatttttacatgccttttctagggaactgTACTTGT CatttacaaaaataCCCGAGATAATGTGTACAAAatcaaaaaagaaggatgttgaaat g" /listShort="lrpC, topB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 476021 /Source="Nicolas_upshifts" /id="U333" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.765234765234765" /psig="0.999000999001" /xcortree=2269 /SigmaFactorBS="aacattcatttttacatgccttttctagggaactgTACTTGT CatttacaaaaataCCCGAGATAATGTGTACAAAatcaaaaaagaaggatgttgaaat g" /listShort="lrpC, topB" /GFF_Attribute="listLong" CDS 476059..476493 /gene="lrpC" /locus_tag="BSU_04250" /old_locus_tag="BSU04250" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:9341680, 10606655, 10913073, 12458218, 16407330, 16528101" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9341680, 10606655, 10913073, 12458218, 16407330, 16528101; Product type r : regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator (Lrp/AsnC family)" /protein_id="NP_388306.1" /db_xref="EnsemblGenomes-Gn:BSU04250" /db_xref="EnsemblGenomes-Tr:CAB12232" /db_xref="GOA:P96582" /db_xref="InterPro:IPR000485" /db_xref="InterPro:IPR011008" /db_xref="InterPro:IPR019887" /db_xref="InterPro:IPR019888" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="PDB:2CFX" /db_xref="SubtiList:BG12056" /db_xref="UniProtKB/Swiss-Prot:P96582" /translation="MKLDQIDLNIIEELKKDSRLSMRELGRKIKLSPPSVTERVRQLE SFGIIKQYTLEVDQKKLGLPVSCIVEATVKNADYERFKSYIQTLPNIEFCYRIAGAAC YMLKINAESLEAVEDFINKTSPYAQTVTHVIFSEIDTKNGRG*" gene 476059..476493 /gene="lrpC" /locus_tag="BSU_04250" /old_locus_tag="BSU04250" promotor_-35 476490..476493 /Source="Nicolas_upshift_promotors" /id="U334" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.685314685314685" /psig="0.988011988011988" /xcortree=2491 /SigmaFactorBS="cgtcactcacgtcattttctcagaaattgacacgaaaaacgg gcgcggTTAGagagtgccgcgcgaagTCTGTTATAATAACAGGATGagcgtgaaagaa a" /listShort="topB, S141, ydaJ" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 476502 /Source="Nicolas_upshifts" /id="U334" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.685314685314685" /psig="0.988011988011988" /xcortree=2491 /SigmaFactorBS="cgtcactcacgtcattttctcagaaattgacacgaaaaacgg gcgcggTTAGagagtgccgcgcgaagTCTGTTATAATAACAGGATGagcgtgaaagaa a" /listShort="topB, S141, ydaJ" /GFF_Attribute="listLong" promotor_-10 476510..476529 /Source="Nicolas_upshift_promotors" /id="U334" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.685314685314685" /psig="0.988011988011988" /xcortree=2491 /SigmaFactorBS="cgtcactcacgtcattttctcagaaattgacacgaaaaacgg gcgcggTTAGagagtgccgcgcgaagTCTGTTATAATAACAGGATGagcgtgaaagaa a" /listShort="topB, S141, ydaJ" /GFF_Attribute="listLong" /label="promotor_-10" CDS 476558..478741 /gene="topB" /locus_tag="BSU_04260" /old_locus_tag="BSU04260" /EC_number="5.99.1.2" /function="16.2: Construct biomass (Anabolism)" /function="16.6: Maintain" /function="16.9: Replicate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1c: Function from experimental evidences in the studied genus; PubMedId: 16192570, 16556226; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="DNA topoisomerase III" /protein_id="NP_388307.1" /db_xref="EnsemblGenomes-Gn:BSU04260" /db_xref="EnsemblGenomes-Tr:CAB12233" /db_xref="GOA:P96583" /db_xref="InterPro:IPR000380" /db_xref="InterPro:IPR003601" /db_xref="InterPro:IPR003602" /db_xref="InterPro:IPR005738" /db_xref="InterPro:IPR006171" /db_xref="InterPro:IPR013497" /db_xref="InterPro:IPR013825" /db_xref="InterPro:IPR023405" /db_xref="InterPro:IPR023406" /db_xref="InterPro:IPR034144" /db_xref="SubtiList:BG11979" /db_xref="UniProtKB/Swiss-Prot:P96583" /translation="MSKTVVLAEKPSVGRDLARVLKCHKKGNGYLEGDQYIVTWALGH LVTLADPEGYGKEFQSWRLEDLPIIPEPLKLVVIKKTGKQFNAVKSQLTRKDVNQIVI ATDAGREGELVARWIIEKANVRKPIKRLWISSVTDKAIKEGFQKLRSGKEYENLYHSA VARAEADWIVGINATRALTTKFNAQLSCGRVQTPTLAMIAKREADIQAFTPVPYYGIR AAVDGMTLTWQDKKSKQTRTFNQDVTSRLLKNLQGKQAVVAELKKTAKKSFAPALYDL TELQRDAHKRFGFSAKETLSVLQKLYEQHKLVTYPRTDSRFLSSDIVPTLKDRLEGME VKPYAQYVSQIKKRGIKSHKGYVNDAKVSDHHAIIPTEEPLVLSSLSDKERKLYDLIA KRFLAVLMPAFEYEETKVIAEIGGETFTAKGKTVQSQGWKAVYDMAEEDDEQEDDRDQ TLPALQKGDTLAVRTLTETSGQTKPPARFNEGTLLSAMENPSAFMQGEEKGLVKTLGE TGGLGTVATRADIIEKLFNSFLIEKKGQDIFITSKGKQLLQLVPEDLKSPALTAEWEQ KLSAIAAGKLKSAVFIKDMKAYAHQTVKEIKNSSQTFRHDNITGTACPECGKMMLKVN GKRGTMLVCQDRECGSRKTIARKTNARCPNCHKRMELRGQGEGQTFACVCGHREKLSV FEKRKNKDKARATKRDVSSYMKKQNKDEPINNALAEQLKKLGLDK*" gene 476558..478741 /gene="topB" /locus_tag="BSU_04260" /old_locus_tag="BSU04260" downshifts 478724 /Source="Nicolas_upshifts" /id="D195" /incds=0 /nref=133 /ntot=245 /MaxReadThrough="3.22367" /MaxDrop="6.18597" /score="23.5229393" /energy="-10.4" /TU="U334" /idTUdmin="U333" /TUdmin=0 /isTUend="TRUE" promotor_-35 478790..478796 /Source="Nicolas_upshift_promotors" /id="U335" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=179 /SigmaFactorBS="tgtgcctatcgcacaggttttttattggacttaggtccTGTT TTCttaatgttcaaaaaGGGAAAAAAAAGCTAGCAAtctgcattttttttcttttata g" /listShort="S141, ydaJ, ydaK" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 478811..478829 /Source="Nicolas_upshift_promotors" /id="U335" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=179 /SigmaFactorBS="tgtgcctatcgcacaggttttttattggacttaggtccTGTT TTCttaatgttcaaaaaGGGAAAAAAAAGCTAGCAAtctgcattttttttcttttata g" /listShort="S141, ydaJ, ydaK" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 478812..478943 /Source="Nicolas_S_feature" /locus_tag="new_478812_478943" /HighExp="Etha, Salt, Heat, Cold, H2O2, G180, LPhT, Oxctl, Paraq, G135" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigB, SigA" /TUshortPSig="1, 0.988" /TUlongSig="NA" /TUlongPSig="NA" /label="S141" upshifts 478812 /Source="Nicolas_upshifts" /id="U335" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=179 /SigmaFactorBS="tgtgcctatcgcacaggttttttattggacttaggtccTGTT TTCttaatgttcaaaaaGGGAAAAAAAAGCTAGCAAtctgcattttttttcttttata g" /listShort="S141, ydaJ, ydaK" /GFF_Attribute="listLong" CDS 478944..480032 /gene="epsJ" /locus_tag="BSU_04270" /old_locus_tag="BSU04270" /function="16.13: Shape" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:15661000, 26078454, 27897378" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15661000, 26078454, 27897378; Product type lp: lipoprotein" /codon_start=1 /transl_table=11 /product="glycosyl hydrolase lipoprotein" /protein_id="NP_388308.1" /db_xref="EnsemblGenomes-Gn:BSU04270" /db_xref="EnsemblGenomes-Tr:CAB12234" /db_xref="GOA:O31486" /db_xref="InterPro:IPR008928" /db_xref="SubtiList:BG12057" /db_xref="UniProtKB/Swiss-Prot:O31486" /translation="MRHVLIAVILFFLSIGLSAGCAEAGNKTQNQSATEVNASPLQPA EYFIYHNLMNDKGLIKTDFSDQPSYLSESLGLWMEFLLSKNDAPHFQDQYQHLTDSFL MSNHLVTWKIQNGQASGTNALIDDMRIMLSLDQAAAKWGRSDYAQTARDIGTSLKTYN MNNGFFTDFYDSQAASKDVTLSYVMPDALAVLKKNGIIDEETEQRNANVLYSAPLKNG FLPKTYSSETKEYTYDSEINLIDQLYAAWHLPEGDEKASVLADWIKQEFQKNGKLYGR YSAYTKEPAVQYESPSVYALAVLFLTKQHENSSVIKAIYDRMNDFEIHDPVKSYYGGY MSGTQTHSFDNLLPLLAERKLFNENIIQ*" gene 478944..480032 /gene="epsJ" /locus_tag="BSU_04270" /old_locus_tag="BSU04270" CDS 480013..480864 /gene="epsK" /locus_tag="BSU_04280" /old_locus_tag="BSU04280" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:23893111, 27897378" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 23893111, 27897378; Product type rc: receptor" /codon_start=1 /transl_table=11 /product="cyclic-di-GMP receptor" /protein_id="NP_388309.1" /db_xref="EnsemblGenomes-Gn:BSU04280" /db_xref="EnsemblGenomes-Tr:CAB12235" /db_xref="GOA:P96585" /db_xref="InterPro:IPR000160" /db_xref="InterPro:IPR029787" /db_xref="SubtiList:BG12058" /db_xref="UniProtKB/Swiss-Prot:P96585" /translation="MKISFSESQKLFAYFSGLIAALSLFIYYVSAQQSEGALILCITF GVIAAGIWFGPIYALAVTLIVLFVLGTLMMFFQTGQTSLFPAEEGLRMLVVWGIALLL FSFISGRIHDITAELRRSMTRLQSEIKSYVAVDRVTGFDNKQRMKLELSEEIKRAERY GNSFVFLLLHMHYFKEFKSLYGEKETDRLFQYVGQQIRTSVRETDKKFRPSDERIGIV LTHTPAEHMPAVLTKLKKQLDTYQLENGKYVSLTFHVCYLPYRNDIQTADQFLEELEN EMMMNEL*" gene 480013..480864 /gene="epsK" /locus_tag="BSU_04280" /old_locus_tag="BSU04280" CDS 480875..482584 /gene="ydaL" /locus_tag="BSU_04290" /old_locus_tag="BSU04290" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 27897378; Product type ph :phenotype" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_388310.1" /db_xref="EnsemblGenomes-Gn:BSU04290" /db_xref="EnsemblGenomes-Tr:CAB12236" /db_xref="GOA:O31487" /db_xref="InterPro:IPR018763" /db_xref="SubtiList:BG12059" /db_xref="UniProtKB/Swiss-Prot:O31487" /translation="MLCVMMLLFSAIASFPVSAQAKDQDAGILIIYSTLDGKESSQVK MLDLLAGHFTSHVTVKKDSDVEASDFKGKDHVIYYGQTKRKLSQKLLSLISGVKKPVV AIGYNAGQISQFSGLSLARKENVFQVHSRSEKADVSLESGLNVLSVSGLKGTALYTFK ADEGTTHSFIWKTKKGNVYIGLTNLLNDNLIVAKQLREAFGEKAGTTLLYLRLEDISP MSDEKLLLQAGTYLHKRHIPFILAVIPVYLNPETGDKVYLSNQPKMVKVLKKLQSMGG SIIVHGYTHAYRYSETGEGFEFWDAKADQPITSGNAEDPPSILEKEQDFPNEQAYHSY LEPFREKEETYTKQKLTRAIEDLTSSGLYPLAFEAPHYTMSEYGYQIASQYFTSIFGQ VQLSSTTWKTSGAPPFVTAPSMLHGMTLYPETIGFVDTSKQNPLGEMEEHISQMIDFE GGVAGGFYHPYLGMKYLPELVDQMERIPDSEWLDLKKTKQTVKTDKVEIHTSGDGTIQ VKNGVSPIYEFFDHHRQTPLEKALWILSAVVLLFVIMFVSYTFYLRATLKKRIFKERR SLG*" gene 480875..482584 /gene="ydaL" /locus_tag="BSU_04290" /old_locus_tag="BSU04290" CDS 482577..483839 /gene="ydaM" /locus_tag="BSU_04300" /old_locus_tag="BSU04300" /EC_number="2.4.-.-" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 27897378, 28296273; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative glycosyltransferase associated to biofilm formation" /protein_id="NP_388311.1" /db_xref="EnsemblGenomes-Gn:BSU04300" /db_xref="EnsemblGenomes-Tr:CAB12237" /db_xref="GOA:P96587" /db_xref="InterPro:IPR029044" /db_xref="SubtiList:BG12060" /db_xref="UniProtKB/Swiss-Prot:P96587" /translation="MGNTLFFISLSLIWVMLLYHMFLMQGGFRHYMTFERNIPKWREN MKELPKVSVLIPAHNEEVVIRQTLKAMVNLYYPKDRLEIIVVNDNSSDRTGDIVNEFS EKYDFIKMVITKPPNAGKGKSSALNSGFAESNGDVICVYDADNTPEKMAVYYLVLGLM NDEKAGAVVGKFRVINAAKTLLTRFINIETICFQWMAQGGRWKWFKIATIPGTNFAIR RSIIEKLGGWDDKALAEDTELTIRVYNLGYHIRFFPAAITWEQEPETWKVWWRQRTRW ARGNQYVVLKFLAQFFKLKRKRIIFDLFYFFFTYFLFFFGVIMSNAIFVVNLFYDLHL SVGFLAMILWILAFFLFMTEVMITLSIEKTEMNKQNFFIVFLMYFTYSQAWIVLVIYS LFVEIKHRLFKQEVKWYKTERYNQHKSG*" gene 482577..483839 /gene="ydaM" /locus_tag="BSU_04300" /old_locus_tag="BSU04300" CDS 483845..485956 /gene="ydaN" /locus_tag="BSU_04310" /old_locus_tag="BSU04310" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 27897378; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative regulator of exopolysaccharide synthesis" /protein_id="NP_388312.1" /db_xref="EnsemblGenomes-Gn:BSU04310" /db_xref="EnsemblGenomes-Tr:CAB12238" /db_xref="GOA:O31488" /db_xref="InterPro:IPR008979" /db_xref="InterPro:IPR018513" /db_xref="SubtiList:BG12061" /db_xref="UniProtKB/Swiss-Prot:O31488" /translation="MKQIMIFLTSFMLLAMTGQTALAKDVQVSGSLLGKSSQEQAKQQ VLTSELITLYGSKDSAELTYQIPAGASSGNQQLVIEYEASNLLISPSSLTVVIDDEPV KTLKLDGDSKRKTVKLNLNKSQSAQGYHNVSLKFYGVMKEGVCVRQDTSGNWIKIYPD SRLTLADSSEAKGTSLDHYPYPFAQSGNTAEETAIVIPDNPSSAEIEAAVKTEGYLKT VDSSVSIAYVTESELKKIDKPTIVIGVDKHWNGKVKKLLKQAGLQAKGENLLLAERVL KAEGKQQPVLFAQAASEDALTKKISVMTDQTYTGQLSGDTLSISKLQQTEKKESDKLT LENFGAGDITIGADKTSSAHYFYPASAVLDENQSAKLSLKLKKSETIQASTAENESAS QAAELKVMINGQPHSVRLDELGKEDKNGFYHVTVKVDPKLLQKNRYIDIQFVTTGLKE NNPCNTTDEEKWVFIDKNSTLSYAIKGMSPSADFQEWPLPYAGNQDQTTLIVLPDTVS QSKLEELSLVTESFGNEAQHSYTVKKSSDVTANDAKGRNLIFIGGINQFSLLKEKSSD LLVPQEKNGSFDVSSFEMLNETTKQVVFTQASVWDSRYTMAVFAPSKGDGTAVTKEII SYLNSNDESATVLNETNSQQVFTNHQQLKSETNSSDAEQPTQDHSQKWMYIGVLALIM VVAAVFIWIAVRRKKRKTDTE*" gene 483845..485956 /gene="ydaN" /locus_tag="BSU_04310" /old_locus_tag="BSU04310" downshifts 485940 /Source="Nicolas_upshifts" /id="D196" /incds=0 /nref=18 /ntot=91 /MaxReadThrough="0.438479999999999" /MaxDrop="4.36576" /score="34.1370207" /energy="-9.9" /TU="NA" /idTUdmin="U336" /TUdmin="-4598" /isTUend="FALSE" promotor_-35 486053..486060 /Source="Nicolas_upshift_promotors" /id="U336" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.976023976023976" /psig="0.998001998001998" /xcortree=2720 /SigmaFactorBS="cattttatttttttctctcagccaataagccTCTTTACAacg tgcgggaacggGAGTATGATCTCTTTTAGAAaacaaatcgcttaatctgaaatcagag c" /listShort="NA, S142, ydaO, mutT, ydaP" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 486075..486094 /Source="Nicolas_upshift_promotors" /id="U336" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.976023976023976" /psig="0.998001998001998" /xcortree=2720 /SigmaFactorBS="cattttatttttttctctcagccaataagccTCTTTACAacg tgcgggaacggGAGTATGATCTCTTTTAGAAaacaaatcgcttaatctgaaatcagag c" /listShort="NA, S142, ydaO, mutT, ydaP" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 486082 /Source="Nicolas_upshifts" /id="U336" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.976023976023976" /psig="0.998001998001998" /xcortree=2720 /SigmaFactorBS="cattttatttttttctctcagccaataagccTCTTTACAacg tgcgggaacggGAGTATGATCTCTTTTAGAAaacaaatcgcttaatctgaaatcagag c" /listShort="NA, S142, ydaO, mutT, ydaP" /GFF_Attribute="listLong" misc_RNA 486092..486235 /gene="swaO" /locus_tag="BSU_misc_RNA_7" /product="ATP-, cyclic di-AMP-sensing riboswitch" /experiment="publication(s) with functional evidences, PMID:15096624, 20511502, 23086297, 25086507, 25086509" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15096624, 20511502, 23086297, 25086507, 25086509; Product type n: RNA" /function="16.3: Control" gene 486092..486235 /gene="swaO" /locus_tag="BSU_misc_RNA_7" downshifts 486233 /Source="Nicolas_upshifts" /id="D197" /incds=0 /nref=10 /ntot=52 /MaxReadThrough="7.43698" /MaxDrop="5.83561" /score="30.4392599" /energy="-14.7" /TU="U336" /idTUdmin="U336" /TUdmin="-4305" /isTUend="FALSE" S_feature 486278..486431 /Source="Nicolas_S_feature" /locus_tag="new_486278_486431" /HighExp="LPhT, LBGstat, LPh, T-1.10H, T-0.40H, G135, G180, T-1.40H, G150, C30" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.998" /TUlongSig="NA" /TUlongPSig="NA" /label="S142" CDS 486432..488255 /gene="kimA" /locus_tag="BSU_04320" /old_locus_tag="BSU04320" /function="16.3: Control" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:15096624, 15849754, 16850406, 20511502, 25086509, 26789423, 28420751" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15096624, 15849754, 16850406, 20511502, 25086509, 26789423, 28420751; Product type t: transporter" /codon_start=1 /transl_table=11 /product="cyclic di-AMP controlled transporter of potassium" /protein_id="NP_388313.1" /db_xref="EnsemblGenomes-Gn:BSU04320" /db_xref="EnsemblGenomes-Tr:CAB12239" /db_xref="GOA:P96589" /db_xref="InterPro:IPR002293" /db_xref="SubtiList:BG12062" /db_xref="UniProtKB/Swiss-Prot:P96589" /translation="MYHSIKRFLIGKPLKSQAAGEQKLTKLKALAMLSSDALSSVAYG TEQILIILATISAAAFWYSIPIAVGVLILLLALILSYRQIIYAYPQGGGAYIVSKENL GEKPGLIAGGSLLVDYILTVAVSISAGTDAITSAFPALHDYHVPIAIFLVLVIMILNL RGLSESASILAYPVYLFVVALLVLIAVGLFKLMTGQIDQPAHHTSLGTPVAGITLFLL LKAFSSGCSALTGVEAISNAIPAFKNPPARNAARTLAMMGILLAILFSGITVLAYGYG TAPKPDETVVSQIASETFGRNVFYYVIQGVTSLILVLAANTGFSAFPQLAFNLARDQY MPRMFTVRGDRLGFSNGIIFLGFASIVLIILFGGQTEHLIPLYAVGVFIPFTLSQTGM CMKWIKQKPKGWIGKMLINSCGALISFMVLSILFVTKFNVVWPVLIFMPIVVLLFFAI KNHYTAVGEQLRIVDKEPEEIKGTVVIVPVAGVTTVVQKSIHYAKSLSDQVIAVHVSF DREQEKKFEKRWEELNNGVRLVTLHSSYRSLVHPFDKFLETVEAKAKKEQFSVMVLFP QFITKKRWHTILHNQSAFLLRVRLFWKKDIMVATLPYHFKK*" gene 486432..488255 /gene="kimA" /locus_tag="BSU_04320" /old_locus_tag="BSU04320" downshifts 488247 /Source="Nicolas_upshifts" /id="D198" /incds=0 /nref=50 /ntot=181 /MaxReadThrough="3.55206" /MaxDrop="4.7232" /score="6.00201196" /energy="-13.9" /TU="U336" /idTUdmin="U336" /TUdmin="-2291" /isTUend="FALSE" CDS 488314..488763 /gene="nudT" /locus_tag="BSU_04330" /old_locus_tag="BSU04330" /EC_number="3.6.1.-" /function="16.8: Protect" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15576788, 16513759; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative NTP pyrophosphohydrolase" /protein_id="NP_388314.1" /db_xref="EnsemblGenomes-Gn:BSU04330" /db_xref="EnsemblGenomes-Tr:CAB12240" /db_xref="GOA:P96590" /db_xref="InterPro:IPR000086" /db_xref="InterPro:IPR015797" /db_xref="InterPro:IPR020084" /db_xref="InterPro:IPR020476" /db_xref="SubtiList:BG11956" /db_xref="UniProtKB/Swiss-Prot:P96590" /translation="MYTQGAFVIVLNESQQILLVKRKDVPLWDLPGGRVDPGESAEEA AVREILEETGYNAALSAKIGVYQRPKFQDEQHLFFGSITGGQAMADGTETAGLKWVSP GRLPLFMVPNRKRQINDFKNGAQDVNVTVKDSGLLAAIDLLKRRLGK*" gene 488314..488763 /gene="nudT" /locus_tag="BSU_04330" /old_locus_tag="BSU04330" promotor_-35 488776..488782 /Source="Nicolas_upshift_promotors" /id="U337" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=192 /SigmaFactorBS="tgttgaaaagaagactgggcaagtgattcaggtctccgGGTT TTAaagcctttctcctgTGGTATTGAAAAAAGGAAAaaggaggatacgttatggcaca c" /listShort="ydaP, S145" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 488797..488815 /Source="Nicolas_upshift_promotors" /id="U337" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=192 /SigmaFactorBS="tgttgaaaagaagactgggcaagtgattcaggtctccgGGTT TTAaagcctttctcctgTGGTATTGAAAAAAGGAAAaaggaggatacgttatggcaca c" /listShort="ydaP, S145" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 488798 /Source="Nicolas_upshifts" /id="U337" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=192 /SigmaFactorBS="tgttgaaaagaagactgggcaagtgattcaggtctccgGGTT TTAaagcctttctcctgTGGTATTGAAAAAAGGAAAaaggaggatacgttatggcaca c" /listShort="ydaP, S145" /GFF_Attribute="listLong" CDS 488830..490554 /gene="poxB" /locus_tag="BSU_04340" /old_locus_tag="BSU04340" /EC_number="1.2.3.3" /function="16.6: Maintain" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 16291680, 16513748, 10220166, 23611909; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="acetyl-phosphate generating pyruvate oxidase" /protein_id="NP_388315.1" /db_xref="EnsemblGenomes-Gn:BSU04340" /db_xref="EnsemblGenomes-Tr:CAB12241" /db_xref="GOA:P96591" /db_xref="InterPro:IPR000399" /db_xref="InterPro:IPR011766" /db_xref="InterPro:IPR012000" /db_xref="InterPro:IPR012001" /db_xref="InterPro:IPR029035" /db_xref="InterPro:IPR029061" /db_xref="SubtiList:BG12063" /db_xref="UniProtKB/Swiss-Prot:P96591" /translation="MAHKTAGQAMTELLEQWGVDHVYGIPGDSINEFIEELRHERNQL KFIQTRHEEVAALAAAAEAKLTGKIGVCLSIAGPGAVHLLNGLYDAKADGAPVLAIAG QVSSGEVGRDYFQEIKLEQMFEDVAVFNREVHSAESLPDLLNQAIRTAYSKKGVAVLS VSDDLFAEKIKREPVYTSPVYIEGNLEPKKEQLVTCAQYINNAKKPIILAGQGMKKAK RELLEFADKAAAPIVVTLPAKGVVPDKHPHFLGNLGQIGTKPAYEAMEECDLLIMLGT SFPYRDYLPDDTPAIQLDSDPAKIGKRYPVTAGLVCDSALGLRELTEYIERKEDRRFL NACTEHMQHWWNEIEKDETEATTPLKPQQVVARLQEAAADDAVLSVDVGTVTVWMARH FKMNANQDFIVSSWLATMGCGLPGAIAASLSEPERQAIAVCGDGGFSMVMQDLPTAVK YKLPITVVILNNENLGMIEYEQQVKGNIDYVTKLQNVDYAAFAESCGAKGIKVTKAEE LAPAFHEALHSDQPVVVDVMIGNEPPLPGKITYGQAKGFSKYMLKNFFENQKFEMPSL KKSLKRLF*" gene 488830..490554 /gene="poxB" /locus_tag="BSU_04340" /old_locus_tag="BSU04340" S_feature complement(489666..490525) /Source="Nicolas_S_feature" /locus_tag="new_489666_490525_c" /HighExp="H2O2, Paraq, G180, G150, Oxctl, Diami, dia15, G135, C30, dia5" /AntisenseName="ydaP" /AntisenseCor="-5.0529608261635599E-2" /AntisenseRegPval="-0.4" /CDS_PredictionProba="NA" /TUshortSig="Sig-, SigA, SigA" /TUshortPSig="0.113, 1, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S143" S_feature complement(490527..490638) /Source="Nicolas_S_feature" /locus_tag="new_490527_490638_c" /HighExp="dia5, M0t45, S0, S2, S1, Paraq, GM 120, Lbstat, MG 5, UNK1" /AntisenseName="ydaP" /AntisenseCor="1.7026698118644101E-2" /AntisenseRegPval="-0.1" /CDS_PredictionProba="NA" /TUshortSig="Sig-, SigA, SigA" /TUshortPSig="0.113, 1, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S144" downshifts 490538 /Source="Nicolas_upshifts" /id="D199" /incds=0 /nref=50 /ntot=166 /MaxReadThrough="5.18566" /MaxDrop="6.66568" /score="7.55338633" /energy="-5.3" /TU="U337" /idTUdmin="U336" /TUdmin=0 /isTUend="TRUE" CDS complement(490546..490749) /locus_tag="BSU_04345" /old_locus_tag="BSU04345" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_009513943.1" /translation="MIRISMQGQMHLPLKQDAFVLLSVSSMAKSVPNTYTDHFMNSNM LKIHLFPKKKKKTRALRAPVFLK*" gene complement(490546..490749) /locus_tag="BSU_04345" /old_locus_tag="BSU04345" downshifts complement(490570) /Source="Nicolas_upshifts" /id="D200" /incds=0 /nref=5 /ntot=55 /MaxReadThrough="4.75809" /MaxDrop="8.06239" /score="11.2659249" /energy="-9.1" /TU="U338,U340,U341" /idTUdmin="U338" /TUdmin="-110" /isTUend="FALSE" promotor_no_box complement(490598..490698) /Source="Nicolas_upshift_promotors" /id="U338" /multdbtbs="-" /comp="M21" /sig="Sig-" /pcomp="0.445554445554446" /psig="0.112887112887113" /xcortree=1496 /SigmaFactorBS="gcatttgtccttttgtctgtttcgagtatggcgaaatcagtt cctaatacatataccgatcattttatgaattcaaacatgctgaaaatacatttgtttc c" /listShort="S144, S143" /GFF_Attribute="listLong" /label="promotor_no_box" promotor_-35 490607..490612 /Source="Nicolas_upshift_promotors" /id="U339" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.914085914085914" /psig="0.914085914085914" /xcortree=1216 /SigmaFactorBS="tgtttttttttttttttttggaaacaaaTGTATTttcagcat gtttgaatTCATAAAATGATCGGTATAtgtattaggaactgatttcgccatactcgaa a" /listShort="S145" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 490629..490647 /Source="Nicolas_upshift_promotors" /id="U339" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.914085914085914" /psig="0.914085914085914" /xcortree=1216 /SigmaFactorBS="tgtttttttttttttttttggaaacaaaTGTATTttcagcat gtttgaatTCATAAAATGATCGGTATAtgtattaggaactgatttcgccatactcgaa a" /listShort="S145" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(490638) /Source="Nicolas_upshifts" /id="U338" /multdbtbs="-" /comp="M21" /sig="Sig-" /pcomp="0.445554445554446" /psig="0.112887112887113" /xcortree=1496 /SigmaFactorBS="gcatttgtccttttgtctgtttcgagtatggcgaaatcagtt cctaatacatataccgatcattttatgaattcaaacatgctgaaaatacatttgtttc c" /listShort="S144, S143" /GFF_Attribute="listLong" S_feature 490639..490854 /Source="Nicolas_S_feature" /locus_tag="new_490639_490854" /HighExp="Etha, S4, S8, S5, C30, S7, B60, S6, Salt, B36" /AntisenseName="ydzK" /AntisenseCor="3.8830946787094797E-2" /AntisenseRegPval="-0.3" /CDS_PredictionProba="NA" /TUshortSig="SigEF, SigB" /TUshortPSig="0.914, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S145" upshifts 490639 /Source="Nicolas_upshifts" /id="U339" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.914085914085914" /psig="0.914085914085914" /xcortree=1216 /SigmaFactorBS="tgtttttttttttttttttggaaacaaaTGTATTttcagcat gtttgaatTCATAAAATGATCGGTATAtgtattaggaactgatttcgccatactcgaa a" /listShort="S145" /GFF_Attribute="listLong" S_feature complement(490705..490776) /Source="Nicolas_S_feature" /locus_tag="new_490705_490776_c" /HighExp="Sw, B60, dia15, dia5, BI, Etha, BC, M9-stat, C90, M0t45" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="1, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S146" downshifts complement(490748) /Source="Nicolas_upshifts" /id="D201" /incds=0 /nref=21 /ntot=191 /MaxReadThrough="5.39949" /MaxDrop="5.81865" /score="3.34912028" /energy="-20.3" /TU="U340,U341" /idTUdmin="U343" /TUdmin=0 /isTUend="TRUE" CDS complement(490777..491043) /gene="ydzK" /locus_tag="BSU_04359" /old_locus_tag="BSU04359" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative membrane protein" /protein_id="YP_003097680.1" /db_xref="EnsemblGenomes-Gn:BSU04359" /db_xref="EnsemblGenomes-Tr:CAX52551" /db_xref="GOA:C0H3V4" /db_xref="UniProtKB/Swiss-Prot:C0H3V4" /translation="MSVFILFYLWIVPIVIGILCSVAAHKSKGKMRVAPGIAMIVLSI ISLITAFTAGHTNFHVFIGGMFLFGTFLVGSAFPFFFGLKKKEK*" gene complement(490777..491043) /gene="ydzK" /locus_tag="BSU_04359" /old_locus_tag="BSU04359" promotor_-10 complement(491059..491078) /Source="Nicolas_upshift_promotors" /id="U340" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.637362637362637" /psig=1 /xcortree=2076 /SigmaFactorBS="cttctaaagccggtttttatttttccgcaaaagctcattgAT ACCCTTtttgacagaaaTTTGTTATGATAGAAGAAAAatcggagttttgatgatgtca g" /listShort="ydzK, S146, S144, S143" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(491077) /Source="Nicolas_upshifts" /id="U340" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.637362637362637" /psig=1 /xcortree=2076 /SigmaFactorBS="cttctaaagccggtttttatttttccgcaaaagctcattgAT ACCCTTtttgacagaaaTTTGTTATGATAGAAGAAAAatcggagttttgatgatgtca g" /listShort="ydzK, S146, S144, S143" /GFF_Attribute="listLong" promotor_-35 complement(491090..491097) /Source="Nicolas_upshift_promotors" /id="U340" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.637362637362637" /psig=1 /xcortree=2076 /SigmaFactorBS="cttctaaagccggtttttatttttccgcaaaagctcattgAT ACCCTTtttgacagaaaTTTGTTATGATAGAAGAAAAatcggagttttgatgatgtca g" /listShort="ydzK, S146, S144, S143" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(491147..492424) /gene="mntH" /locus_tag="BSU_04360" /old_locus_tag="BSU04360" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:12029030, 12950915, 14580210, 15849754, 16850406, 27573840, 27748968" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12029030, 12950915, 14580210, 15849754, 16850406, 27573840, 27748968; Product type t: transporter" /codon_start=1 /transl_table=11 /product="proton-coupled manganese transporter" /protein_id="NP_388317.1" /db_xref="EnsemblGenomes-Gn:BSU04360" /db_xref="EnsemblGenomes-Tr:CAB12243" /db_xref="GOA:P96593" /db_xref="InterPro:IPR001046" /db_xref="SubtiList:BG12065" /db_xref="UniProtKB/Swiss-Prot:P96593" /translation="MMNKDITAQSPRSKAVQDALDGKIRGFRGLLPFLGPAFIAAIAY IDPGNFATNISAGSKYGYMLLWVILFSNIMALLIQSLSAKLGIATGKNLPEVAREEFP KPVSIGLWIQGELVIIATDLAEFIGAALGLYLLFGIPMLEASIIAAIGSFAILELQRR GYRSLEAGIAGMLFVVVIAFALQTFFAKPDAVSVMKGLFVPAFHGTDSVLLAAGILGA TVMPHAIYLHSALTQRRVVGKTDAERKKIFRFEFIDILIAMLIAGAINASMLIVAAAL FFKNGLFVEDLDVAFQQFGHLVSPMSAALFGIGLLVAGLSSSSVGTLSGDVIMQGFIN YRIPLYVRRFITIIPPILIIASGVNPTTALVLSQVVLSFGIAFALIPLIMFTSNKRIM GSLINAKWITVVSWLIAVLIVALNVFLIVDTFR*" gene complement(491147..492424) /gene="mntH" /locus_tag="BSU_04360" /old_locus_tag="BSU04360" downshifts complement(491166) /Source="Nicolas_upshifts" /id="D202" /incds=0 /nref=170 /ntot=242 /MaxReadThrough="5.8826" /MaxDrop="4.8109" /score="28.3182556" /energy="-9.6" /TU="U341,U343" /idTUdmin="U342" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(492486..492505) /Source="Nicolas_upshift_promotors" /id="U341" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.528471528471528" /psig=1 /xcortree=1525 /SigmaFactorBS="ggaaaaattcagaagtgtattttgaacattttcGGTTGACAa gaaaccgggatGGTCATATGATGTAGATAAAataatttgccttaaggaaactctttgt t" /listShort="mntH, ydzK, S146, S144, S143" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(492498) /Source="Nicolas_upshifts" /id="U341" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.528471528471528" /psig=1 /xcortree=1525 /SigmaFactorBS="ggaaaaattcagaagtgtattttgaacattttcGGTTGACAa gaaaccgggatGGTCATATGATGTAGATAAAataatttgccttaaggaaactctttgt t" /listShort="mntH, ydzK, S146, S144, S143" /GFF_Attribute="listLong" S_feature complement(492500..492577) /Source="Nicolas_S_feature" /locus_tag="new_492500_492577_c" /HighExp="S6, S8, S7, Etha, S5, Salt, BT, Heat, B36, B60" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigK, SigB" /TUshortPSig="1, 0.993" /TUlongSig="NA" /TUlongPSig="NA" /label="S147" promotor_-35 complement(492518..492525) /Source="Nicolas_upshift_promotors" /id="U341" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.528471528471528" /psig=1 /xcortree=1525 /SigmaFactorBS="ggaaaaattcagaagtgtattttgaacattttcGGTTGACAa gaaaccgggatGGTCATATGATGTAGATAAAataatttgccttaaggaaactctttgt t" /listShort="mntH, ydzK, S146, S144, S143" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(492561..492580) /Source="Nicolas_upshift_promotors" /id="U342" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1312 /SigmaFactorBS="aggcatcgtttcgaaatgaaacgatgtctttttaTATGGGAC CTtatcacgaatcccTACATATCATGTTACATAACagggaaaaattcagaagtgtatt t" /listShort="S147, mntH" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(492577) /Source="Nicolas_upshifts" /id="U342" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1312 /SigmaFactorBS="aggcatcgtttcgaaatgaaacgatgtctttttaTATGGGAC CTtatcacgaatcccTACATATCATGTTACATAACagggaaaaattcagaagtgtatt t" /listShort="S147, mntH" /GFF_Attribute="listLong" promotor_-35 complement(492594..492603) /Source="Nicolas_upshift_promotors" /id="U342" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1312 /SigmaFactorBS="aggcatcgtttcgaaatgaaacgatgtctttttaTATGGGAC CTtatcacgaatcccTACATATCATGTTACATAACagggaaaaattcagaagtgtatt t" /listShort="S147, mntH" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(492654..492911) /gene="ydaS" /locus_tag="BSU_04370" /old_locus_tag="BSU04370" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_388318.1" /db_xref="EnsemblGenomes-Gn:BSU04370" /db_xref="EnsemblGenomes-Tr:CAB12244" /db_xref="GOA:P96594" /db_xref="InterPro:IPR007341" /db_xref="SubtiList:BG12066" /db_xref="UniProtKB/Swiss-Prot:P96594" /translation="MLSFLVSLVVAIVIGLIGSAIVGNRLPGGIFGSMIAGLIGAWIG HGLLGTWGPSLAGFAIFPAIIGAAIFVFLLGLIFRGLRKEA*" gene complement(492654..492911) /gene="ydaS" /locus_tag="BSU_04370" /old_locus_tag="BSU04370" downshifts complement(492662) /Source="Nicolas_upshifts" /id="D203" /incds=0 /nref=7 /ntot=33 /MaxReadThrough="4.70076" /MaxDrop="4.7213" /score="7.04635537" /energy="-13.4" /TU="U343" /idTUdmin="U342" /TUdmin="-1496" /isTUend="FALSE" downshifts complement(492728) /Source="Nicolas_upshifts" /id="D204" /incds=1 /nref=2 /ntot=69 /MaxReadThrough="7.55545" /MaxDrop="2.8244" /score="7.04635537" /energy="-13.4" /TU="U343" /idTUdmin="U342" /TUdmin="-1562" /isTUend="FALSE" CDS complement(492989..493441) /gene="ydaT" /locus_tag="BSU_04380" /old_locus_tag="BSU04380" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_388319.1" /db_xref="EnsemblGenomes-Gn:BSU04380" /db_xref="EnsemblGenomes-Tr:CAB12245" /db_xref="InterPro:IPR018691" /db_xref="SubtiList:BG12067" /db_xref="UniProtKB/Swiss-Prot:P96595" /translation="MPWSMKDYPASLKNLEKPVRKKAIDIANAMIDEGYEEGRAIPIA TSKAKEWAENASTDEIDDFLTHDDETERDADPSSGSGPELMNKAEHVIKHKKGWAVKA EGAKRVSEIKDTKKEAIERAKEIAAHKGTEVIVHLADGSVQRKIKTGS*" gene complement(492989..493441) /gene="ydaT" /locus_tag="BSU_04380" /old_locus_tag="BSU04380" promotor_-10 complement(493460..493478) /Source="Nicolas_upshift_promotors" /id="U343" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp="0.993006993006993" /psig="0.993006993006993" /xcortree=230 /SigmaFactorBS="ttttttctactatatagtataccttcattttttcggatgCGT TTTTatttttcacctgcGGGTACCATTTTTATAAAAggaaaaggagtgatagacatgc c" /listShort="ydaT, ydaS, S147, mntH, ydzK" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(493477) /Source="Nicolas_upshifts" /id="U343" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp="0.993006993006993" /psig="0.993006993006993" /xcortree=230 /SigmaFactorBS="ttttttctactatatagtataccttcattttttcggatgCGT TTTTatttttcacctgcGGGTACCATTTTTATAAAAggaaaaggagtgatagacatgc c" /listShort="ydaT, ydaS, S147, mntH, ydzK" /GFF_Attribute="listLong" promotor_-35 complement(493492..493498) /Source="Nicolas_upshift_promotors" /id="U343" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp="0.993006993006993" /psig="0.993006993006993" /xcortree=230 /SigmaFactorBS="ttttttctactatatagtataccttcattttttcggatgCGT TTTTatttttcacctgcGGGTACCATTTTTATAAAAggaaaaggagtgatagacatgc c" /listShort="ydaT, ydaS, S147, mntH, ydzK" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 493510 /Source="Nicolas_upshifts" /id="U344" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.795204795204795" /psig="0.993006993006993" /xcortree=2375 /SigmaFactorBS="ctccttttccttttataaaaatggtacccgcaggtgaaaaat aaaaacgcatccgaaaaaatgaaggtATACTATATAGTAGAAAAAAcggaagggaagt g" /listShort="ydbA" /GFF_Attribute="listLong" misc_feature 493518..493537 /Source="Nicolas_upshift_promotors" /id="U344" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.795204795204795" /psig="0.993006993006993" /xcortree=2375 /SigmaFactorBS="ctccttttccttttataaaaatggtacccgcaggtgaaaaat aaaaacgcatccgaaaaaatgaaggtATACTATATAGTAGAAAAAAcggaagggaagt g" /listShort="ydbA" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" CDS 493559..494377 /gene="ydbA" /locus_tag="BSU_04390" /old_locus_tag="BSU04390" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_388320.1" /db_xref="EnsemblGenomes-Gn:BSU04390" /db_xref="EnsemblGenomes-Tr:CAB12246" /db_xref="InterPro:IPR024787" /db_xref="SubtiList:BG12068" /db_xref="UniProtKB/Swiss-Prot:P96596" /translation="MPTERKEDLHQQLKEIEKWEKDQQKVWFWEKLSRLPFQLLDKLT PEFIQKKIGKLLDEVGSFVQTGGQYLTSEKQIIRMFQKKLPEEIFESLEDIRKAPLPV MDEIAEGMGKNRTNAATVQGATTGVGGVFTLAADIPAVLGLSLKTLQDIAVAYGYDPK EKKERVFIVKCLQLTSADVVGKRSILQELKHYDQDRTYKNVASQIQGWREVVLGYRDT FGWKKLFQIVPVAGMVFGAAANRSTLNDITETGMMLYKKRRILERLKETEREME*" gene 493559..494377 /gene="ydbA" /locus_tag="BSU_04390" /old_locus_tag="BSU04390" downshifts 494368 /Source="Nicolas_upshifts" /id="D205" /incds=0 /nref=118 /ntot=223 /MaxReadThrough="0.66117" /MaxDrop="4.41502" /score="5.38936313" /energy="-9.2" /TU="NA" /idTUdmin="U344" /TUdmin=0 /isTUend="TRUE" promotor_-35 494445..494451 /Source="Nicolas_upshift_promotors" /id="U345" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=219 /SigmaFactorBS="ttttagtggaaacatacccaatgtgttttgttTGTTTAAaag aattgtgagcGGGAATACAACAACCAACAccaattaaaggaggaattcaaaatggcag a" /listShort="gsiB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 494465..494483 /Source="Nicolas_upshift_promotors" /id="U345" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=219 /SigmaFactorBS="ttttagtggaaacatacccaatgtgttttgttTGTTTAAaag aattgtgagcGGGAATACAACAACCAACAccaattaaaggaggaattcaaaatggcag a" /listShort="gsiB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 494473 /Source="Nicolas_upshifts" /id="U345" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=219 /SigmaFactorBS="ttttagtggaaacatacccaatgtgttttgttTGTTTAAaag aattgtgagcGGGAATACAACAACCAACAccaattaaaggaggaattcaaaatggcag a" /listShort="gsiB" /GFF_Attribute="listLong" CDS 494506..494877 /gene="gsiB" /locus_tag="BSU_04400" /old_locus_tag="BSU04400" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:7651322, 9669336, 9763714, 12562800, 21421783" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7651322, 9669336, 9763714, 12562800, 21421783; Product type f: factor" /codon_start=1 /transl_table=11 /product="general stress protein glucose starvation induced" /protein_id="NP_388321.1" /db_xref="EnsemblGenomes-Gn:BSU04400" /db_xref="EnsemblGenomes-Tr:CAB12247" /db_xref="InterPro:IPR019626" /db_xref="SubtiList:BG10826" /db_xref="UniProtKB/Swiss-Prot:P26907" /translation="MADNNKMSREEAGRKGGETTSKNHDKEFYQEIGQKGGEATSKNH DKEFYQEIGEKGGEATSKNHDKEFYQEIGEKGGEATSENHDKEFYQEIGRKGGEATSK NHDKEFYQEIGSKGGNARNND*" gene 494506..494877 /gene="gsiB" /locus_tag="BSU_04400" /old_locus_tag="BSU04400" downshifts complement(494510) /Source="Nicolas_upshifts" /id="D206" /incds=0 /nref=1 /ntot=25 /MaxReadThrough="1.50212" /MaxDrop="4.6705" /score="-7.76438364" /energy="-14.2" /TU="NA" /idTUdmin="U346" /TUdmin=0 /isTUend="TRUE" downshifts 494894 /Source="Nicolas_upshifts" /id="D207" /incds=0 /nref=153 /ntot=219 /MaxReadThrough="3.75525" /MaxDrop="8.3301" /score="39.7307477" /energy="-16.6" /TU="U345" /idTUdmin="U345" /TUdmin="-24" /isTUend="FALSE" upshifts complement(494928) /Source="Nicolas_upshifts" /id="U346" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.738261738261738" /psig="0.00899100899100899" /xcortree=120 /SigmaFactorBS="cttattgtatctcaatagcggcataaattgagaagattccaa aaaaaagcgatcCAGCtgatgtgccggatcgcttttttatttacaggttgtctgcctt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" misc_feature complement(494931..494934) /Source="Nicolas_upshift_promotors" /id="U346" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.738261738261738" /psig="0.00899100899100899" /xcortree=120 /SigmaFactorBS="cttattgtatctcaatagcggcataaattgagaagattccaa aaaaaagcgatcCAGCtgatgtgccggatcgcttttttatttacaggttgtctgcctt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" promotor_-35 494956..494963 /Source="Nicolas_upshift_promotors" /id="U347" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.98101898101898" /psig=1 /xcortree=2941 /SigmaFactorBS="ggcacatcagctggatcgcttttttttggaatctTCTCAATT tatgccgctatTGAGATACAATAAGTGAAAAaggggttttcgctaatgtccaagatgc a" /listShort="ydbB, ydbC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 494975..494994 /Source="Nicolas_upshift_promotors" /id="U347" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.98101898101898" /psig=1 /xcortree=2941 /SigmaFactorBS="ggcacatcagctggatcgcttttttttggaatctTCTCAATT tatgccgctatTGAGATACAATAAGTGAAAAaggggttttcgctaatgtccaagatgc a" /listShort="ydbB, ydbC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 494982 /Source="Nicolas_upshifts" /id="U347" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.98101898101898" /psig=1 /xcortree=2941 /SigmaFactorBS="ggcacatcagctggatcgcttttttttggaatctTCTCAATT tatgccgctatTGAGATACAATAAGTGAAAAaggggttttcgctaatgtccaagatgc a" /listShort="ydbB, ydbC" /GFF_Attribute="listLong" CDS 495009..495350 /gene="ydbB" /locus_tag="BSU_04410" /old_locus_tag="BSU04410" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 10704478; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative enzyme; cupin family" /protein_id="NP_388322.1" /db_xref="EnsemblGenomes-Gn:BSU04410" /db_xref="EnsemblGenomes-Tr:CAB12248" /db_xref="GOA:P96597" /db_xref="InterPro:IPR011051" /db_xref="InterPro:IPR013096" /db_xref="InterPro:IPR014710" /db_xref="InterPro:IPR019780" /db_xref="SubtiList:BG12069" /db_xref="UniProtKB/Swiss-Prot:P96597" /translation="MSKMQNLLAIANEVKEKHANFSISEVNDHCVRLAVFTGEYDWHH HPDSDELFIVLEGELLIDFKDKETAVLKANDSLLIPKGTVHRTRSYVRTVNLCVEHKQ AETVIIEEQPC*" gene 495009..495350 /gene="ydbB" /locus_tag="BSU_04410" /old_locus_tag="BSU04410" CDS 495344..495703 /gene="ydbC" /locus_tag="BSU_04420" /old_locus_tag="BSU04420" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_388323.1" /db_xref="EnsemblGenomes-Gn:BSU04420" /db_xref="EnsemblGenomes-Tr:CAB12249" /db_xref="InterPro:IPR011008" /db_xref="InterPro:IPR032555" /db_xref="SubtiList:BG12070" /db_xref="UniProtKB/Swiss-Prot:P96598" /translation="MLIKKMICEVDAANAEAFAKAQSQWEALSHISGFIKQAGGWRKT IDEPLTAEIISVWENREAYDHFMENEHDSIYEENDQKAVILSIEVTVYEEDKPFVHDL LHNPDIRYEPNWTVLKA*" gene 495344..495703 /gene="ydbC" /locus_tag="BSU_04420" /old_locus_tag="BSU04420" S_feature complement(495406..495699) /Source="Nicolas_S_feature" /locus_tag="new_495406_495699_c" /HighExp="Etha, Salt, M9-stat, C30, Heat, Sw, B60, S8, C90, UNK1" /AntisenseName="ydbC" /AntisenseCor="0.16172626521480701" /AntisenseRegPval="-2.1" /CDS_PredictionProba="NA" /TUshortSig="SigB" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S148" downshifts 495644 /Source="Nicolas_upshifts" /id="D208" /incds=0 /nref=2 /ntot=130 /MaxReadThrough="1.8663" /MaxDrop="2.67081" /score="39.7307477" /energy="-16.6" /TU="NA" /idTUdmin="U347" /TUdmin=0 /isTUend="TRUE" downshifts 495688 /Source="Nicolas_upshifts" /id="D209" /incds=0 /nref=1 /ntot=28 /MaxReadThrough="0.252220000000001" /MaxDrop="2.61185" /score="39.7307477" /energy="-16.6" /TU="NA" /idTUdmin="U347" /TUdmin=44 /isTUend="FALSE" CDS complement(495740..496561) /gene="ydbD" /locus_tag="BSU_04430" /old_locus_tag="BSU04430" /EC_number="1.11.1.6" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15231799; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative manganese-containing catalase" /protein_id="NP_388324.1" /db_xref="EnsemblGenomes-Gn:BSU04430" /db_xref="EnsemblGenomes-Tr:CAB12250" /db_xref="GOA:P80878" /db_xref="InterPro:IPR007760" /db_xref="InterPro:IPR009078" /db_xref="InterPro:IPR012347" /db_xref="InterPro:IPR027407" /db_xref="SubtiList:BG12071" /db_xref="UniProtKB/Swiss-Prot:P80878" /translation="MFKHTKMLQHPAKPDRPDPLFAKKMQEILGGQFGEISVAMQYLF QGWNTRGNEKYKDLLMDTATEELGHVEMIATMIARLLEDAPLDQQEKAAEDPVIGSIL GGMNPHHAIVSGLGAMPESSTGVPWSGGYIVASGNLLADFRANLNAESQGRLQVARLF EMTDDKGVKDMLSFLLARDTMHQNQWLAAIKELEAQEGPVVPGTFPKALEKQEFSHQL INFSEGEVSAEQNWLNEKAPDGEAFEYVKEAKTFGEKPELKPAPPFVHNTLPGRE*" gene complement(495740..496561) /gene="ydbD" /locus_tag="BSU_04430" /old_locus_tag="BSU04430" downshifts complement(495744) /Source="Nicolas_upshifts" /id="D210" /incds=0 /nref=62 /ntot=214 /MaxReadThrough="4.23505" /MaxDrop="6.82771" /score="-6.55917314" /energy="-13.1" /TU="U348" /idTUdmin="U348" /TUdmin="-310" /isTUend="FALSE" promotor_-10 complement(496583..496601) /Source="Nicolas_upshift_promotors" /id="U348" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=193 /SigmaFactorBS="gctgcgaaaagattcatagttcccatctcgatacgctgtttt tCGTTTATctttctatcgatcGGAAATATAAAAAGAGATAaacgaaaaaggagatggg t" /listShort="ydbD, S148" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(496604) /Source="Nicolas_upshifts" /id="U348" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=193 /SigmaFactorBS="gctgcgaaaagattcatagttcccatctcgatacgctgtttt tCGTTTATctttctatcgatcGGAAATATAAAAAGAGATAaacgaaaaaggagatggg t" /listShort="ydbD, S148" /GFF_Attribute="listLong" promotor_-35 complement(496615..496621) /Source="Nicolas_upshift_promotors" /id="U348" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=193 /SigmaFactorBS="gctgcgaaaagattcatagttcccatctcgatacgctgtttt tCGTTTATctttctatcgatcGGAAATATAAAAAGAGATAaacgaaaaaggagatggg t" /listShort="ydbD, S148" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(496646..497698) /gene="dctB" /locus_tag="BSU_04440" /old_locus_tag="BSU04440" /function="16.12: Sense" /experiment="publication(s) with functional evidences, PMID:1809844, 10708364, 11566984, 24375102" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1809844, 10708364, 11566984, 24375102; Product type rc: receptor" /codon_start=1 /transl_table=11 /product="membrane bound C4-dicarboxylate binding sensor protein" /protein_id="NP_388325.1" /db_xref="EnsemblGenomes-Gn:BSU04440" /db_xref="EnsemblGenomes-Tr:CAB12251" /db_xref="GOA:P96600" /db_xref="InterPro:IPR004682" /db_xref="InterPro:IPR018389" /db_xref="SubtiList:BG12072" /db_xref="UniProtKB/Swiss-Prot:P96600" /translation="MKSLLACLALMIAGIATALFIGFHDHTGNKKIVYDDDQEGLQDQ IVFKFSHVVAENTPKGLAANKFADLVNEKSGGKIKIEVFPNGSLYSDIEEIEALQNGD VQFIAPSTSKLGMLSPEWGVLDLPYAFTDYNAVKKGLNGSIGTQLFDSLKKNQLKGLA YWTNGFKQITTNQGPVKTPDDLKGQDLRIMQSDVIEDQFKLLGATPHQESFNSTFQLL ENNVVDGEENTISNIYSKKFYNVQDYLTISSHGYLGYAVMTDEHFWKAQTPETRRILT EAMKETTEWNETYAEQMNKEQLEEIKKNSAIHIYELSDKEKQEWMKRLDPVYRQYEPI FGRELIRELLELRKDS*" gene complement(496646..497698) /gene="dctB" /locus_tag="BSU_04440" /old_locus_tag="BSU04440" promotor_-35 496958..496965 /Source="Nicolas_upshift_promotors" /id="U349" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.882117882117882" /psig=1 /xcortree=1811 /SigmaFactorBS="cagtcatgacagcgtagccgagataaccgtggctgctTATTG TCAaatagtcctgaacaTTATAAAATTTTTTAGAATAgatgtttgaaattgtattttc t" /listShort="S149, dctS" /GFF_Attribute="listLong" /label="promotor_-35" S_feature 496980..497767 /Source="Nicolas_S_feature" /locus_tag="new_496980_497767" /HighExp="LBGstat, Diami, T-0.40H, T0.0H, T0.30H, Heat, UNK1, GM-0.1, MG 90, Fru" /AntisenseName="dctB" /AntisenseCor="0.64205060306327899" /AntisenseRegPval="-31.9" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S149" promotor_-10 496980..496999 /Source="Nicolas_upshift_promotors" /id="U349" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.882117882117882" /psig=1 /xcortree=1811 /SigmaFactorBS="cagtcatgacagcgtagccgagataaccgtggctgctTATTG TCAaatagtcctgaacaTTATAAAATTTTTTAGAATAgatgtttgaaattgtattttc t" /listShort="S149, dctS" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 496981 /Source="Nicolas_upshifts" /id="U349" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.882117882117882" /psig=1 /xcortree=1811 /SigmaFactorBS="cagtcatgacagcgtagccgagataaccgtggctgctTATTG TCAaatagtcctgaacaTTATAAAATTTTTTAGAATAgatgtttgaaattgtattttc t" /listShort="S149, dctS" /GFF_Attribute="listLong" promotor_-10 complement(497711..497730) /Source="Nicolas_upshift_promotors" /id="U350" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.515484515484515" /psig="0.937062937062937" /xcortree=1551 /SigmaFactorBS="tttgttcatcagcttctcctttcagGTCTTTACgaatgtcat agccCCCATTATCCTTAACATAGGggagggcttttcatgaagagtttgcttgcatgtc t" /listShort="dctB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(497716) /Source="Nicolas_upshifts" /id="U350" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.515484515484515" /psig="0.937062937062937" /xcortree=1551 /SigmaFactorBS="tttgttcatcagcttctcctttcagGTCTTTACgaatgtcat agccCCCATTATCCTTAACATAGGggagggcttttcatgaagagtttgcttgcatgtc t" /listShort="dctB" /GFF_Attribute="listLong" promotor_-35 complement(497744..497751) /Source="Nicolas_upshift_promotors" /id="U350" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.515484515484515" /psig="0.937062937062937" /xcortree=1551 /SigmaFactorBS="tttgttcatcagcttctcctttcagGTCTTTACgaatgtcat agccCCCATTATCCTTAACATAGGggagggcttttcatgaagagtttgcttgcatgtc t" /listShort="dctB" /GFF_Attribute="listLong" /label="promotor_-35" CDS 497768..499375 /gene="dctS" /locus_tag="BSU_04450" /old_locus_tag="BSU04450" /function="16.3: Control" /function="16.12: Sense" /experiment="publication(s) with functional evidences, PMID:10627041, 11717295, 1290636, 12949159, 24375102" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10627041, 11717295, 1290636, 12949159, 24375102; Product type rc: receptor" /codon_start=1 /transl_table=11 /product="two-component sensor histidine kinase" /protein_id="NP_388326.1" /db_xref="EnsemblGenomes-Gn:BSU04450" /db_xref="EnsemblGenomes-Tr:CAB12252" /db_xref="GOA:P96601" /db_xref="InterPro:IPR000014" /db_xref="InterPro:IPR003594" /db_xref="InterPro:IPR004358" /db_xref="InterPro:IPR005467" /db_xref="InterPro:IPR016120" /db_xref="InterPro:IPR029151" /db_xref="InterPro:IPR033463" /db_xref="InterPro:IPR035965" /db_xref="InterPro:IPR036890" /db_xref="SubtiList:BG12073" /db_xref="UniProtKB/Swiss-Prot:P96601" /translation="MNKKKLSIRWKITILSYILVIFSFLIGGIVLIGNIQHTEERELK KRLMNTARTVSEMTEVKEALARKKQTEAVRHAVEEIRMINEADYIVVMDMNHIRYTHP VSTSIGKKSEGADEEAAFAEHIYFSEAKGEIGTAVRAFYPVKDQDLNQIGVVLVGKTL PGIADILLHLKRDIAFIVVLTLGFGLAGSFLLARHIKKQMFQLEPHEIVRMYEERTAT FHSMNEGVIAIDNRLVITIFNEKAKQIFEVQGDLIGKVIWEVLKDSRLPEIVERNKAV YNEEIRVSGKVIMSSRIPIVMKKKVIGAVAIFQDRTEAAKMAEELTGVRNFVEALRVQ NHEHMNKLHTIAGLIQLGKSEKALQLAFQASTEQENVTEFLHRSIQNDAAAGLLLSKI RRGRELGIAVHIDENSSLQQFPEHVDQHDIVVLLGNLIENAFGSFETVQSEDKRIDIS IEQTDDILAILIEDNGCGIEPTHMPRLYDKGFTVNKTGGTGYGLYLVKQIIDKGSGTI EVDSHAGQGTSFSIVFPMKGEEAQHGS*" gene 497768..499375 /gene="dctS" /locus_tag="BSU_04450" /old_locus_tag="BSU04450" CDS 499365..500045 /gene="dctR" /locus_tag="BSU_04460" /old_locus_tag="BSU04460" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:10627041, 11717295, 1290636, 12949159" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10627041, 11717295, 1290636, 12949159; Product type r: regulator" /codon_start=1 /transl_table=11 /product="two-component response regulator" /protein_id="NP_388327.1" /db_xref="EnsemblGenomes-Gn:BSU04460" /db_xref="EnsemblGenomes-Tr:CAB12253" /db_xref="GOA:P96602" /db_xref="InterPro:IPR001034" /db_xref="InterPro:IPR001789" /db_xref="InterPro:IPR011006" /db_xref="InterPro:IPR024187" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG12074" /db_xref="UniProtKB/Swiss-Prot:P96602" /translation="MARKEWKVLLIEDDPMVQEVNKDFITTVKGVTVCATAGNGEEGM KLIKEEQPDLVILDVYMPKKDGIKTLQEIRKQKLEVDVIVVSAAKDKETISLMLQNGA VDYILKPFKLERMRQALEKYKQYKQKIEANDTLSQEQLDAILNIPQQAVQDLPKGLNH FTMNEVTAFLKQQTASLSAEEVAKALGIARVTARRYLDYLEKTGIIKLDVQYGGVGRP VNRYVLKG*" gene 499365..500045 /gene="dctR" /locus_tag="BSU_04460" /old_locus_tag="BSU04460" S_feature 500046..500120 /Source="Nicolas_S_feature" /locus_tag="new_500046_500120" /HighExp="Sw, Diami, Mt0, G150, BI, Lbstat, M40t45, Lbtran, Mal, Oxctl" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="NA" /TUshortPSig="NA" /TUlongSig="NA" /TUlongPSig="NA" /label="S150" promotor_-35 500087..500094 /Source="Nicolas_upshift_promotors" /id="U351" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.450549450549451" /psig="0.96003996003996" /xcortree=1558 /SigmaFactorBS="accaaaatgtccgttatgatcataaACTTCCCCagactgtat gaaaaCGCTATCATTCTAGTAAGaaagacacaaaaggcgaataggacagggggatgaa g" /listShort="dctP" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 500109..500126 /Source="Nicolas_upshift_promotors" /id="U351" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.450549450549451" /psig="0.96003996003996" /xcortree=1558 /SigmaFactorBS="accaaaatgtccgttatgatcataaACTTCCCCagactgtat gaaaaCGCTATCATTCTAGTAAGaaagacacaaaaggcgaataggacagggggatgaa g" /listShort="dctP" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 500122 /Source="Nicolas_upshifts" /id="U351" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.450549450549451" /psig="0.96003996003996" /xcortree=1558 /SigmaFactorBS="accaaaatgtccgttatgatcataaACTTCCCCagactgtat gaaaaCGCTATCATTCTAGTAAGaaagacacaaaaggcgaataggacagggggatgaa g" /listShort="dctP" /GFF_Attribute="listLong" CDS 500166..501431 /gene="dctP" /locus_tag="BSU_04470" /old_locus_tag="BSU04470" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:10627041, 10708364, 12949159, 15849754, 16850406, 20363944, 22389480" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10627041, 10708364, 12949159, 15849754, 16850406, 20363944, 22389480; Product type t: transporter" /codon_start=1 /transl_table=11 /product="C4-dicarboxylate transport protein" /protein_id="NP_388328.1" /db_xref="EnsemblGenomes-Gn:BSU04470" /db_xref="EnsemblGenomes-Tr:CAB12254" /db_xref="GOA:P96603" /db_xref="InterPro:IPR001991" /db_xref="InterPro:IPR018107" /db_xref="InterPro:IPR023954" /db_xref="InterPro:IPR036458" /db_xref="SubtiList:BG12075" /db_xref="UniProtKB/Swiss-Prot:P96603" /translation="MKLFKNLTVQVITAVIIGVIVGLVWPDVGKEMKPLGDTFINAVK MVIAPIIFFTIVLGIAKMGDMKKVGKVGGKAFIYFEVVTTLALIIGLFVVNIMKPGAG LDYSKLEKGDVSQYTQNGGQGIDWIEFITHIVPSNMVDAFAKGDILQVLFFSILFGVG LAALGEKGKSVIDFFDKVSHVFFKIIGYIMRAAPIGAFGAMAYTIGHFGLDSIKPLAS LMMSVYITMFLFVFVALNIICKLYGFSLWNYLRFIKDELLIVLGTSSSESVLPRMMDK MERYGCSKSVVGLVIPTGYSFNLDGTSIYLSMATVFLAQVFGVDLSIGQQITIILVLM LTSKGAAGVTGSGFIVLASTLSALQVIPLEGLALLLGVDRFMSEGRAIVNLIGNGIAT IIVAKSENEFDEAKSIEAVEGMKKMKTAV*" gene 500166..501431 /gene="dctP" /locus_tag="BSU_04470" /old_locus_tag="BSU04470" downshifts 501424 /Source="Nicolas_upshifts" /id="D211" /incds=0 /nref=175 /ntot=235 /MaxReadThrough="3.99042" /MaxDrop="7.04798" /score="45.0636559" /energy="-12.6" /TU="NA" /idTUdmin="U351" /TUdmin=0 /isTUend="TRUE" downshifts complement(501478) /Source="Nicolas_upshifts" /id="D212" /incds=0 /nref=1 /ntot=9 /MaxReadThrough="0.588190000000001" /MaxDrop="3.06255" /score="19.3433396" /energy="-12.6" /TU="NA" /idTUdmin="U350" /TUdmin="-4818" /isTUend="FALSE" misc_feature 501515..501532 /Source="Nicolas_upshift_promotors" /id="U352" /multdbtbs="-" /comp="M3" /sig="Sig-" /pcomp="0.423576423576424" /psig="0.483516483516484" /xcortree=1457 /SigmaFactorBS="gtttttttaattgtttaagaattattaaggtaaggacagaga cctcagcatttttttgTTATATAATTTACAAATGgatactatattgaatgaaggacgt t" /listShort="ydbI, S151, ydbJ, ydbK, ydbL, S152, ydbM" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 501517 /Source="Nicolas_upshifts" /id="U352" /multdbtbs="-" /comp="M3" /sig="Sig-" /pcomp="0.423576423576424" /psig="0.483516483516484" /xcortree=1457 /SigmaFactorBS="gtttttttaattgtttaagaattattaaggtaaggacagaga cctcagcatttttttgTTATATAATTTACAAATGgatactatattgaatgaaggacgt t" /listShort="ydbI, S151, ydbJ, ydbK, ydbL, S152, ydbM" /GFF_Attribute="listLong" CDS 501579..502631 /gene="ydbI" /locus_tag="BSU_04480" /old_locus_tag="BSU04480" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative integral inner membrane protein" /protein_id="NP_388329.1" /db_xref="EnsemblGenomes-Gn:BSU04480" /db_xref="EnsemblGenomes-Tr:CAB12255" /db_xref="GOA:P96604" /db_xref="InterPro:IPR002549" /db_xref="SubtiList:BG12076" /db_xref="UniProtKB/Swiss-Prot:P96604" /translation="MAALVKFFQHPGVRRFSIFVVLTGVLYLFKSMINLILLTFIFTF LMDRLELVVRQFVSQFFRVSQRVVITFLYMLLAVLLTVGGFVFYPVVAAQIQQLVKQI KHIAYHPDSIPFFDEITSVFGDINISSYVKEGFNVVYTYLADISTFGLQVVMALILSM FFLFEKKRLSEFMAKFKTSKLRVFYEEIAFFGSKFARTFGKVLEAQFIIALVNCILTF IALWIMHFPQLFGLSIMVFFLGLIPVAGVVISLIPLSIIAYSTGGGMYVLYIVLVIFA IHAIETYFLNPKLMSAKTELPIFFTFTVLIFSEHFFGIWGLIIGIPIFVFLLDILDVT NKEDRSKGPRENSDKK*" gene 501579..502631 /gene="ydbI" /locus_tag="BSU_04480" /old_locus_tag="BSU04480" S_feature 502632..502875 /Source="Nicolas_S_feature" /locus_tag="new_502632_502875" /HighExp="S8, S5, S6, LoTm, S7, S3, LBGstat, LBGexp, Paraq, Sw" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.87223499999999998" /TUshortSig="Sig-" /TUshortPSig="0.484" /TUlongSig="NA" /TUlongPSig="NA" /label="S151" downshifts 502832 /Source="Nicolas_upshifts" /id="D213" /incds=0 /nref=6 /ntot=45 /MaxReadThrough="6.05001" /MaxDrop="3.52626" /score="17.6400305" /energy="-12.4" /TU="U352" /idTUdmin="U351" /TUdmin=1408 /isTUend="FALSE" CDS 502908..503834 /gene="ydbJ" /locus_tag="BSU_04490" /old_locus_tag="BSU04490" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative ABC transporter (ATP-binding subunit)" /protein_id="NP_388330.1" /db_xref="EnsemblGenomes-Gn:BSU04490" /db_xref="EnsemblGenomes-Tr:CAB12256" /db_xref="GOA:P96605" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR017871" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG12077" /db_xref="UniProtKB/Swiss-Prot:P96605" /translation="MAEPILHIEGLDKKIGSKQILKQISMDVMEGEIIGLLGPNGSGK TTLIRIIVGLLKQNSGSVTISGFQHDTEFEKAMEAVGAIVENPEFYPYLTGWENLKHF ANMHKKIADERLDEVVERVGLTSAIHDKVKTYSLGMRQRLGIAQAILHRPKLLILDEP TNGLDPAGMKDFRDHIKELAEMEGTAVLFATHLLREVEDLCDRVIIIQKGEIKAEVSL QGTDQTTEKAIIEVQPQEKALNWLTGNQYQAESQDGTIVVEVAKENIPELNRSLVGQD LNVFSITPYTQSLEDEFIKATTAHQEEGEELV*" gene 502908..503834 /gene="ydbJ" /locus_tag="BSU_04490" /old_locus_tag="BSU04490" CDS 503854..504594 /gene="ydbK" /locus_tag="BSU_04500" /old_locus_tag="BSU04500" /function="16.1: Circulate" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 12486040, 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative efflux ABC-transporter (permease subunit)" /protein_id="NP_388331.1" /db_xref="EnsemblGenomes-Gn:BSU04500" /db_xref="EnsemblGenomes-Tr:CAB12257" /db_xref="GOA:P96606" /db_xref="InterPro:IPR032688" /db_xref="SubtiList:BG12078" /db_xref="UniProtKB/Swiss-Prot:P96606" /translation="MKLFNRKVTLVSLILMAVFQFFMALIIKRIVISAGTDENFIGYL SYTPSLNILLQALTIVIAATIVSMEFDKKTIKFLLIRPVKRQKVFWSKLITVVMVSFY LYLAYYILALLFGLLFFGTSVTAESKTLLVNTLALIGSNWLEAVMMGLFGLLCSSLFR NSAVAVVVSFVVLYGASTLVQLMKLFENKWGSFLLFANTDFTQYRSGETALFSGMTPL FSIGILIIHAIFFIVVGWWCFCKRDVRV*" gene 503854..504594 /gene="ydbK" /locus_tag="BSU_04500" /old_locus_tag="BSU04500" misc_feature 504653..504672 /Source="Nicolas_upshift_promotors" /id="U353" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.612387612387612" /psig="0.99000999000999" /xcortree=1624 /SigmaFactorBS="caaggaatgacatttttgtgaaaaagctcacgtaaatcaata tcatttgatatttTGGTTTATACTAAAGGTACTgacggaggtgtctcgattgaggaac t" /listShort="ydbL, S152, ydbM" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 504658 /Source="Nicolas_upshifts" /id="U353" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.612387612387612" /psig="0.99000999000999" /xcortree=1624 /SigmaFactorBS="caaggaatgacatttttgtgaaaaagctcacgtaaatcaata tcatttgatatttTGGTTTATACTAAAGGTACTgacggaggtgtctcgattgaggaac t" /listShort="ydbL, S152, ydbM" /GFF_Attribute="listLong" CDS 504689..505024 /gene="ydbL" /locus_tag="BSU_04510" /old_locus_tag="BSU04510" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 17928292; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative glyco-prenyl flippase subunit" /protein_id="NP_388332.1" /db_xref="EnsemblGenomes-Gn:BSU04510" /db_xref="EnsemblGenomes-Tr:CAB12258" /db_xref="GOA:P96607" /db_xref="SubtiList:BG12079" /db_xref="UniProtKB/Swiss-Prot:P96607" /translation="MRNFITALPIVLLLGFSFVSFMFQFEHLVYFRLALGLFSLVGLY MIYKMKTGIRYFIIYLYASWIVLAAVTAFEEPIFSSFFFGGLVMTMGYLTYMLIYLGM KQDRDANPV*" gene 504689..505024 /gene="ydbL" /locus_tag="BSU_04510" /old_locus_tag="BSU04510" downshifts 504999 /Source="Nicolas_upshifts" /id="D214" /incds=0 /nref=2 /ntot=99 /MaxReadThrough="5.33473" /MaxDrop="5.39081" /score="25.8152101" /energy="-18.4" /TU="U352,U353" /idTUdmin="U352" /TUdmin="-1177" /isTUend="FALSE" S_feature 505044..505113 /Source="Nicolas_S_feature" /locus_tag="new_505044_505113" /HighExp="ferm, nit, S2, S0, Gly, M0t45, M0t90, Lbstat, M/G, M40t90" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, Sig-" /TUshortPSig="0.99, 0.484" /TUlongSig="NA" /TUlongPSig="NA" /label="S152" promotor_-35 505079..505086 /Source="Nicolas_upshift_promotors" /id="U354" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.572427572427572" /psig="0.973026973026973" /xcortree=1741 /SigmaFactorBS="ttttctatactgggcaaaaggttaaCAGTTGCGgaaaaatgg caggAAATCTATAATACATATTAAatttatcggaattaaaactggggggctgccggat g" /listShort="ydbM" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 505100..505119 /Source="Nicolas_upshift_promotors" /id="U354" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.572427572427572" /psig="0.973026973026973" /xcortree=1741 /SigmaFactorBS="ttttctatactgggcaaaaggttaaCAGTTGCGgaaaaatgg caggAAATCTATAATACATATTAAatttatcggaattaaaactggggggctgccggat g" /listShort="ydbM" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 505114 /Source="Nicolas_upshifts" /id="U354" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.572427572427572" /psig="0.973026973026973" /xcortree=1741 /SigmaFactorBS="ttttctatactgggcaaaaggttaaCAGTTGCGgaaaaatgg caggAAATCTATAATACATATTAAatttatcggaattaaaactggggggctgccggat g" /listShort="ydbM" /GFF_Attribute="listLong" CDS 505152..506297 /gene="ydbM" /locus_tag="BSU_04520" /old_locus_tag="BSU04520" /EC_number="1.3.99.-" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 12193636, 16513748, 22720735; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative acyl-CoA dehydrogenase" /protein_id="NP_388333.1" /db_xref="EnsemblGenomes-Gn:BSU04520" /db_xref="EnsemblGenomes-Tr:CAB12259" /db_xref="GOA:P96608" /db_xref="InterPro:IPR006091" /db_xref="InterPro:IPR009100" /db_xref="InterPro:IPR013107" /db_xref="InterPro:IPR013786" /db_xref="InterPro:IPR036250" /db_xref="InterPro:IPR037069" /db_xref="SubtiList:BG12080" /db_xref="UniProtKB/Swiss-Prot:P96608" /translation="MSLFIQNDQQRQWMEKIGRIADEFQQTAAEDDEQGRFPAEKIQK LRDAGYTALTLPASHGGGGISVYDMLLFQERLARGDAPTALSIGWHLSVIGELGEGNS WDEDVFAFVAKEVQNGAVINRAATEAKTGSPTRGGRPGTHAVKKDGKWAVNGRKTFTT MSQALDYFLVTAWIEDKQTTGVFLIHKDDPGLSIEETWDMMAMRATGSHDLVLNEVML DENKLVELLQGPRGAKPNGWLLHIPAIYLGVAQAARDYAVQFASEYSPNSLNGPIKNV PAVQQRTGEMELELLNARHFLFHIAQLYDDPVRRPHLTSELGAAKHIVTNAALSVVDK AMRIVGAKSLERTNPLQRYYRDVRAGLHNPPMDDAVIHKLAAEAFES*" gene 505152..506297 /gene="ydbM" /locus_tag="BSU_04520" /old_locus_tag="BSU04520" downshifts 506279 /Source="Nicolas_upshifts" /id="D215" /incds=0 /nref=13 /ntot=123 /MaxReadThrough="2.90782" /MaxDrop="4.20573" /score="9.48525091" /energy="-7" /TU="NA" /idTUdmin="U353" /TUdmin="-7" /isTUend="TRUE" CDS complement(506322..506501) /gene="fbpB" /locus_tag="BSU_04530" /old_locus_tag="BSU04530" /experiment="publication(s) with functional evidences, PMID:12354229, 16428414, 18697947, 22427629" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12354229, 16428414, 18697947, 22427629; Product type r: regulator" /codon_start=1 /transl_table=11 /product="regulator of iron homeostasis" /protein_id="NP_388334.1" /db_xref="EnsemblGenomes-Gn:BSU04530" /db_xref="EnsemblGenomes-Tr:CAB12260" /db_xref="GOA:P96609" /db_xref="InterPro:IPR025004" /db_xref="SubtiList:BG12081" /db_xref="UniProtKB/Swiss-Prot:P96609" /translation="MNTNMSGGRRSMPKRKVKTYQQLIQENKEAIMGNPKLMNVIYDR IDRKHQKNLQEQNNT*" gene complement(506322..506501) /gene="fbpB" /locus_tag="BSU_04530" /old_locus_tag="BSU04530" downshifts complement(506340) /Source="Nicolas_upshifts" /id="D216" /incds=0 /nref=158 /ntot=207 /MaxReadThrough="2.35872" /MaxDrop="6.38199" /score="26.3317207" /energy="-7" /TU="NA" /idTUdmin="U355" /TUdmin=0 /isTUend="TRUE" CDS complement(506455..506619) /gene="fbpA" /locus_tag="BSU_04536" /old_locus_tag="BSU04536" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:18697947" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 18697947; Product type r: regulator" /codon_start=1 /transl_table=11 /product="regulator of iron homeostasis" /protein_id="YP_009513944.1" /db_xref="EnsemblGenomes-Gn:BSU04536" /db_xref="EnsemblGenomes-Tr:CCQ48594" /db_xref="InterPro:IPR025072" /db_xref="UniProtKB/TrEMBL:L8ECQ9" /translation="MTPQSAEIRKKQLIHLLIQNGIYKKSKRHLYELSLTELESEYKH VRRAPEHAEA*" gene complement(506455..506619) /gene="fbpA" /locus_tag="BSU_04536" /old_locus_tag="BSU04536" S_feature complement(506502..506670) /Source="Nicolas_S_feature" /locus_tag="new_506502_506670_c" /HighExp="B60, nit, B36, Lbexp, GM 15, GM 10, dia0, S2, GM 25, BI" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.99141199999999996" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S153" promotor_-10 complement(506662..506681) /Source="Nicolas_upshift_promotors" /id="U355" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.93906093906094" /psig=1 /xcortree=2111 /SigmaFactorBS="taaattggccaagaataggactcttttcaTCTTTACAggcta ttgcggacaTTGTATACTGAAGTTAATTGataatgattatcaatatcgtttgattgga g" /listShort="S153, ydbN" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(506672) /Source="Nicolas_upshifts" /id="U355" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.93906093906094" /psig=1 /xcortree=2111 /SigmaFactorBS="taaattggccaagaataggactcttttcaTCTTTACAggcta ttgcggacaTTGTATACTGAAGTTAATTGataatgattatcaatatcgtttgattgga g" /listShort="S153, ydbN" /GFF_Attribute="listLong" promotor_-35 complement(506696..506703) /Source="Nicolas_upshift_promotors" /id="U355" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.93906093906094" /psig=1 /xcortree=2111 /SigmaFactorBS="taaattggccaagaataggactcttttcaTCTTTACAggcta ttgcggacaTTGTATACTGAAGTTAATTGataatgattatcaatatcgtttgattgga g" /listShort="S153, ydbN" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 506811..506816 /Source="Nicolas_upshift_promotors" /id="U356" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.933066933066933" /psig="0.933066933066933" /xcortree=1191 /SigmaFactorBS="tgctgtcgaaatattccgcttcattgaacgcacccTGCTATt tttcatgttttgaaCCATACTATGTAATAGAATggaggctggtattcaatggagcgga c" /listShort="ydbO" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 506832..506850 /Source="Nicolas_upshift_promotors" /id="U356" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.933066933066933" /psig="0.933066933066933" /xcortree=1191 /SigmaFactorBS="tgctgtcgaaatattccgcttcattgaacgcacccTGCTATt tttcatgttttgaaCCATACTATGTAATAGAATggaggctggtattcaatggagcgga c" /listShort="ydbO" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 506836 /Source="Nicolas_upshifts" /id="U356" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.933066933066933" /psig="0.933066933066933" /xcortree=1191 /SigmaFactorBS="tgctgtcgaaatattccgcttcattgaacgcacccTGCTATt tttcatgttttgaaCCATACTATGTAATAGAATggaggctggtattcaatggagcgga c" /listShort="ydbO" /GFF_Attribute="listLong" CDS 506866..507738 /gene="ydbO" /locus_tag="BSU_04540" /old_locus_tag="BSU04540" /function="16.8: Protect" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative cation efflux system" /protein_id="NP_388335.1" /db_xref="EnsemblGenomes-Gn:BSU04540" /db_xref="EnsemblGenomes-Tr:CAB12261" /db_xref="GOA:P96610" /db_xref="InterPro:IPR002524" /db_xref="InterPro:IPR027469" /db_xref="InterPro:IPR027470" /db_xref="InterPro:IPR036837" /db_xref="SubtiList:BG12082" /db_xref="UniProtKB/Swiss-Prot:P96610" /translation="MERTENLKKGEKGALLNIFAYVILAVVKLVIGILYHSEALRADG LNNGTDIVASVAVLIGLRISQRPADSDHPYGHYRAETISSLVASFIMMAVGIEVLIGG GKAIAGGTTETPNLIAAWTALGSAVFMYGIYLYNKRLAASIKSSALMAAAKDSRSDAF VSAGAFIGVFSSQLKLPWVDPVTAFIIGIIICKTAWDIFKDASHSLTDGFHLKDLEPY KQTVGRIENVHRLKDVKARYLGSTVHIEMVITVDPKLTVEEGHGVADEVEDKIKHEHD VTHVHVHVEPDDIK*" gene 506866..507738 /gene="ydbO" /locus_tag="BSU_04540" /old_locus_tag="BSU04540" promotor_-35 507102..507111 /Source="Nicolas_upshift_promotors" /id="U357" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1650 /SigmaFactorBS="gctgacagcgatcatccatacggccattatcgggcTGAAACA ATTtcgtctcttgttGCGTCTTTTATTATGAtggcagtcggcattgaagtgttaatcg g" /listShort="S155, S156, ddl, murF, S157, S158, cshA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 507124..507139 /Source="Nicolas_upshift_promotors" /id="U357" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1650 /SigmaFactorBS="gctgacagcgatcatccatacggccattatcgggcTGAAACA ATTtcgtctcttgttGCGTCTTTTATTATGAtggcagtcggcattgaagtgttaatcg g" /listShort="S155, S156, ddl, murF, S157, S158, cshA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 507127 /Source="Nicolas_upshifts" /id="U357" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1650 /SigmaFactorBS="gctgacagcgatcatccatacggccattatcgggcTGAAACA ATTtcgtctcttgttGCGTCTTTTATTATGAtggcagtcggcattgaagtgttaatcg g" /listShort="S155, S156, ddl, murF, S157, S158, cshA" /GFF_Attribute="listLong" S_feature complement(507683..507752) /Source="Nicolas_S_feature" /locus_tag="new_507683_507752_c" /HighExp="LPhT, dia15, dia5, Diami, Etha, Lbtran, LBGtran, LBGstat, Mt0, M0t45" /AntisenseName="ydbO" /AntisenseCor="0.18463882527998399" /AntisenseRegPval="-2.6" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S154" downshifts complement(507726) /Source="Nicolas_upshifts" /id="D217" /incds=0 /nref=145 /ntot=242 /MaxReadThrough="3.07579" /MaxDrop="6.00116" /score="9.69023537" /energy="-12.3" /TU="U359" /idTUdmin="U359" /TUdmin="-198" /isTUend="FALSE" S_feature 507739..508088 /Source="Nicolas_S_feature" /locus_tag="new_507739_508088" /HighExp="Salt, Paraq, G135, ferm, Oxctl, T-0.40H, G150, Lbexp, T3.0H, T2.30H" /AntisenseName="ydbP" /AntisenseCor="-0.27800721625230801" /AntisenseRegPval="-5.4" /CDS_PredictionProba="NA" /TUshortSig="SigWXY" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S155" CDS complement(507753..508073) /gene="ydbP" /locus_tag="BSU_04550" /old_locus_tag="BSU04550" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 10482513; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative thioredoxin or thiol-disulfide isomerase" /protein_id="NP_388336.1" /db_xref="EnsemblGenomes-Gn:BSU04550" /db_xref="EnsemblGenomes-Tr:CAB12262" /db_xref="GOA:P96611" /db_xref="InterPro:IPR005746" /db_xref="InterPro:IPR013766" /db_xref="InterPro:IPR036249" /db_xref="SubtiList:BG12083" /db_xref="UniProtKB/Swiss-Prot:P96611" /translation="MKKITTNEQFNELIQSDKEIIVKFYADWCPDCTRMNMFIGDILE EYNQNDWYELNKDELPDLAEKYQVMGIPSLLIFKNGEKTAHLHSANAKTPEEVTEFLS EHIS*" gene complement(507753..508073) /gene="ydbP" /locus_tag="BSU_04550" /old_locus_tag="BSU04550" promotor_-35 508069..508073 /Source="Nicolas_upshift_promotors" /id="U358" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.65034965034965" /psig="0.298701298701299" /xcortree=1554 /SigmaFactorBS="tgaatcagttcattaaattgttcgtttgttgtgatttttTTC ATatgtcacaTCTCCTTTTCAATGCcattttaatataaaataaaaaggaattacatac a" /listShort="S156, ddl, murF, S157, S158, cshA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 508082..508096 /Source="Nicolas_upshift_promotors" /id="U358" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.65034965034965" /psig="0.298701298701299" /xcortree=1554 /SigmaFactorBS="tgaatcagttcattaaattgttcgtttgttgtgatttttTTC ATatgtcacaTCTCCTTTTCAATGCcattttaatataaaataaaaaggaattacatac a" /listShort="S156, ddl, murF, S157, S158, cshA" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 508090..508247 /Source="Nicolas_S_feature" /locus_tag="new_508090_508247" /HighExp="Lbexp, dia0, LBGexp, H2O2, Paraq, Oxctl, G180, Salt, M0t45, Mt0" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="Sig-, SigWXY" /TUshortPSig="0.299, 0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S156" upshifts 508090 /Source="Nicolas_upshifts" /id="U358" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.65034965034965" /psig="0.298701298701299" /xcortree=1554 /SigmaFactorBS="tgaatcagttcattaaattgttcgtttgttgtgatttttTTC ATatgtcacaTCTCCTTTTCAATGCcattttaatataaaataaaaaggaattacatac a" /listShort="S156, ddl, murF, S157, S158, cshA" /GFF_Attribute="listLong" promotor_-10 complement(508094..508113) /Source="Nicolas_upshift_promotors" /id="U359" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.98001998001998" /psig=1 /xcortree=2021 /SigmaFactorBS="gatctaattatttttgggcatgctgatgttgaatgCATTTGT AtgtaattccttttTATTTTATATTAAAATGGCAttgaaaaggagatgtgacatatga a" /listShort="ydbP, S154" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(508109) /Source="Nicolas_upshifts" /id="U359" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.98001998001998" /psig=1 /xcortree=2021 /SigmaFactorBS="gatctaattatttttgggcatgctgatgttgaatgCATTTGT AtgtaattccttttTATTTTATATTAAAATGGCAttgaaaaggagatgtgacatatga a" /listShort="ydbP, S154" /GFF_Attribute="listLong" promotor_-35 complement(508127..508134) /Source="Nicolas_upshift_promotors" /id="U359" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.98001998001998" /psig=1 /xcortree=2021 /SigmaFactorBS="gatctaattatttttgggcatgctgatgttgaatgCATTTGT AtgtaattccttttTATTTTATATTAAAATGGCAttgaaaaggagatgtgacatatga a" /listShort="ydbP, S154" /GFF_Attribute="listLong" /label="promotor_-35" CDS 508248..509312 /gene="ddlA" /locus_tag="BSU_04560" /old_locus_tag="BSU04560" /EC_number="6.3.2.4" /function="16.13: Shape" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 8662022, 12682299, 22407814; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="D-alanyl-D-alanine ligase A" /protein_id="NP_388337.1" /db_xref="EnsemblGenomes-Gn:BSU04560" /db_xref="EnsemblGenomes-Tr:CAB12263" /db_xref="GOA:P96612" /db_xref="InterPro:IPR000291" /db_xref="InterPro:IPR005905" /db_xref="InterPro:IPR011095" /db_xref="InterPro:IPR011127" /db_xref="InterPro:IPR011761" /db_xref="InterPro:IPR013815" /db_xref="InterPro:IPR016185" /db_xref="SubtiList:BG11932" /db_xref="UniProtKB/Swiss-Prot:P96612" /translation="MYGGKSAEHNVSLQTALAVIKALNTEKFDIHPIYITEKGEWVRG ARLTEPVSNVKMLQFEQGGSAFSPAALNQEMFPQEASQQNEAIDVVFPLLHGPNGEDG TIQGMLELLNIPYVGNGVLASSAGMDKVVMKHLFAQVGLAQAKYAAFLKKDWTRSPKE SCEEVEQELGYPCFVKPANLGSSVGISKCRNREELQKAFELAFQYDRKVVVEEGINGR EIEIGVLGNDDPKCSVVGEIAPKTDFYDYKAKYEDGDTDLMIPAIVTDEEYATISDMA IKAFKAIDGSGLVRADFFLTADGEVLINEVNTMPGFTPFSMFPLLWKEAGVEYADLIE QLVELAKERHAEKQLIKHTF*" gene 508248..509312 /gene="ddlA" /locus_tag="BSU_04560" /old_locus_tag="BSU04560" downshifts 509300 /Source="Nicolas_upshifts" /id="D218" /incds=0 /nref=1 /ntot=59 /MaxReadThrough="5.68418" /MaxDrop="2.53103" /score="3.92144467" /energy="-9.6" /TU="U357,U358" /idTUdmin="U356" /TUdmin=2310 /isTUend="FALSE" CDS 509384..510757 /gene="murF" /locus_tag="BSU_04570" /old_locus_tag="BSU04570" /EC_number="6.3.2.10" /function="16.13: Shape" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 12682299, 17714441; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate-D-alanyl-D-alanine ligase" /protein_id="NP_388338.1" /db_xref="EnsemblGenomes-Gn:BSU04570" /db_xref="EnsemblGenomes-Tr:CAB12264" /db_xref="GOA:P96613" /db_xref="InterPro:IPR000713" /db_xref="InterPro:IPR004101" /db_xref="InterPro:IPR005863" /db_xref="InterPro:IPR013221" /db_xref="InterPro:IPR035911" /db_xref="InterPro:IPR036565" /db_xref="InterPro:IPR036615" /db_xref="SubtiList:BG12084" /db_xref="UniProtKB/Swiss-Prot:P96613" /translation="MIKRTVKNIAEMVKGTLANPQYEQTVIHGVATDTRKLEQHQLFI PLKGERFDGHSFVEQAFEAGVAAVLWDRSVPNPPENHAVILVDDTLTALQQLAKAYLQ ELGTRVIGVTGSNGKTTTKDMIHAVLGTQYRVHKTGGNFNNHIGLPLTVLAMPENTEI AVLEMGMSAKGEIDLLSRLANPDAAVITNIGESHMQDLGSREGIAEAKLEIINGLKED GVLIYIGDEPLLQNAYSCQTKTYGTGTHNDYQLQDVSQSEEGTHFTIKGIENTFFIPI LGKHNVMNAMAAIAAGAYFGIAPEDAAKGLSGLKVTGMRLELIKTDSGLSIINDAYNA SPTSMKAAIQLTESLEGYGKKMLVLGDMLELGDLEETFHKECGAVISPDKIDRVFTYG KLGAFIAEGALKHFEKDRVSHYTEKKDLLQAVKENASKGDLILFKASRGMKLEEIVKD LIESPLS*" gene 509384..510757 /gene="murF" /locus_tag="BSU_04570" /old_locus_tag="BSU04570" promotor_-35 510788..510794 /Source="Nicolas_upshift_promotors" /id="U360" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=849 /SigmaFactorBS="gaaaatattttgcgaaaaaacgcatattgcATCATAAaataa cctgatatGCAAACACTAATgtatgccggccgaaaattatgtatatctggccggctgc g" /listShort="S157, S158, cshA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 510808..510819 /Source="Nicolas_upshift_promotors" /id="U360" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=849 /SigmaFactorBS="gaaaatattttgcgaaaaaacgcatattgcATCATAAaataa cctgatatGCAAACACTAATgtatgccggccgaaaattatgtatatctggccggctgc g" /listShort="S157, S158, cshA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 510818 /Source="Nicolas_upshifts" /id="U360" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=849 /SigmaFactorBS="gaaaatattttgcgaaaaaacgcatattgcATCATAAaataa cctgatatGCAAACACTAATgtatgccggccgaaaattatgtatatctggccggctgc g" /listShort="S157, S158, cshA" /GFF_Attribute="listLong" misc_feature 510861..510880 /Source="Nicolas_upshift_promotors" /id="U361" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.958041958041958" /psig=1 /xcortree=2138 /SigmaFactorBS="tgatatgcaaacactaatgtatgccggccgaaaattatgtat atctggccggctgcggcTATGATACAATATATATAGGttatttcgcgatacgaacata t" /listShort="S157, S158, cshA" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" S_feature 510862..511036 /Source="Nicolas_S_feature" /locus_tag="new_510862_511036" /HighExp="Cold, ferm, nit, G135, S5, LBGexp, G150, S8, S7, BI" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.76694499999999999" /TUshortSig="SigA, SigGF, Sig-, SigWXY" /TUshortPSig="1, 1, 0.299, 0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S157" upshifts 510862 /Source="Nicolas_upshifts" /id="U361" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.958041958041958" /psig=1 /xcortree=2138 /SigmaFactorBS="tgatatgcaaacactaatgtatgccggccgaaaattatgtat atctggccggctgcggcTATGATACAATATATATAGGttatttcgcgatacgaacata t" /listShort="S157, S158, cshA" /GFF_Attribute="listLong" promotor_-35 511004..511011 /Source="Nicolas_upshift_promotors" /id="U362" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.586413586413586" /psig=1 /xcortree=1884 /SigmaFactorBS="tcgagatgccgatctgcttctcatctTATTGAAAaacaaata gtgtaaTGGTAAGATAAAACTTAAAGtaattcgggctttgtatacggatggatcctgt c" /listShort="S158, cshA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 511026..511045 /Source="Nicolas_upshift_promotors" /id="U362" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.586413586413586" /psig=1 /xcortree=1884 /SigmaFactorBS="tcgagatgccgatctgcttctcatctTATTGAAAaacaaata gtgtaaTGGTAAGATAAAACTTAAAGtaattcgggctttgtatacggatggatcctgt c" /listShort="S158, cshA" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 511038..511105 /Source="Nicolas_S_feature" /locus_tag="new_511038_511105" /HighExp="Cold, G150, T-3.40H, HPh, Salt, LPh, G180, G135, Oxctl, T-5.40H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA, SigGF, Sig-, SigWXY" /TUshortPSig="1, 1, 1, 0.299, 0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S158" upshifts 511038 /Source="Nicolas_upshifts" /id="U362" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.586413586413586" /psig=1 /xcortree=1884 /SigmaFactorBS="tcgagatgccgatctgcttctcatctTATTGAAAaacaaata gtgtaaTGGTAAGATAAAACTTAAAGtaattcgggctttgtatacggatggatcctgt c" /listShort="S158, cshA" /GFF_Attribute="listLong" CDS 511157..512641 /gene="cshA" /locus_tag="BSU_04580" /old_locus_tag="BSU04580" /EC_number="3.6.1.-" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:16352840, 27965645" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16352840, 27965645; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="ATP-dependent RNA helicase; cold shock" /protein_id="NP_388339.2" /db_xref="EnsemblGenomes-Gn:BSU04580" /db_xref="EnsemblGenomes-Tr:CAB12265" /db_xref="GOA:P96614" /db_xref="InterPro:IPR000629" /db_xref="InterPro:IPR001650" /db_xref="InterPro:IPR011545" /db_xref="InterPro:IPR014001" /db_xref="InterPro:IPR014014" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR030880" /db_xref="SubtiList:BG12085" /db_xref="UniProtKB/Swiss-Prot:P96614" /translation="MTITFQDFNLSSDLMKAINRMGFEEATPIQAQTIPLGLSNKDVI GQAQTGTGKTAAFGIPLVEKINPESPNIQAIVIAPTRELAIQVSEELYKIGQDKRAKV LPIYGGQDIGRQIRALKKNPNIIVGTPGRLLDHINRRTIRLNNVNTVVMDEADEMLNM GFIDDIESILSNVPSEHQTLLFSATMPAPIKRIAERFMTEPEHVKVKAKEMTVSNIQQ FYLEVQERKKFDTLTRLLDIQSPELAIVFGRTKRRVDELAEALNLRGYAAEGIHGDLT QAKRMVALRKFKEGAIEVLVATDVAARGLDISGVTHVYNFDVPQDPESYVHRIGRTGR AGKTGMAMTFITPREKSMLRAIEQTTKRKMDRMKEPTLDEALEGQQQVTVERLRTTIS ENNLNFYMTAAAELLEDHDAVTVVAAAIKMATKEPDDTPVRLTDEAPMVSKRYKNQRS SKRRDGQGGGYRGGKGKSNNRSSYDKKRSNDRRSSGDRRQKKSY*" gene 511157..512641 /gene="cshA" /locus_tag="BSU_04580" /old_locus_tag="BSU04580" downshifts 512634 /Source="Nicolas_upshifts" /id="D219" /incds=0 /nref=309 /ntot=313 /MaxReadThrough="1.91428" /MaxDrop="8.13079" /score="26.104757" /energy="-13.1" /TU="NA" /idTUdmin="U358" /TUdmin="-10" /isTUend="TRUE" S_feature 512754..512813 /Source="Nicolas_S_feature" /locus_tag="new_512754_512813" /HighExp="Etha, LBGexp, G180, Cold, Lbtran, dia0, G150, BMM, UNK1, MG-0.1" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigWXY" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S159" promotor_-35 512754..512763 /Source="Nicolas_upshift_promotors" /id="U363" /multdbtbs="SigW" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1673 /SigmaFactorBS="tttgttattcagcaaactttcagctgacggaagccatttttc tctgtatgcttaagaaTGAAACCTTTctgtaaaagagACGTATAAATAACGACgaaaa a" /listShort="S159, ydbS, ydbT, S160, S161, acpS, S162, ydcC" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 512756 /Source="Nicolas_upshifts" /id="U363" /multdbtbs="SigW" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1673 /SigmaFactorBS="tttgttattcagcaaactttcagctgacggaagccatttttc tctgtatgcttaagaaTGAAACCTTTctgtaaaagagACGTATAAATAACGACgaaaa a" /listShort="S159, ydbS, ydbT, S160, S161, acpS, S162, ydcC" /GFF_Attribute="listLong" promotor_-10 512775..512790 /Source="Nicolas_upshift_promotors" /id="U363" /multdbtbs="SigW" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1673 /SigmaFactorBS="tttgttattcagcaaactttcagctgacggaagccatttttc tctgtatgcttaagaaTGAAACCTTTctgtaaaagagACGTATAAATAACGACgaaaa a" /listShort="S159, ydbS, ydbT, S160, S161, acpS, S162, ydcC" /GFF_Attribute="listLong" /label="promotor_-10" CDS 512814..513293 /gene="ydbS" /locus_tag="BSU_04590" /old_locus_tag="BSU04590" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:16629676" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16629676; Product type ph: phenotype" /codon_start=1 /transl_table=11 /product="resistance to heterologous antibiotics" /protein_id="NP_388340.1" /db_xref="EnsemblGenomes-Gn:BSU04590" /db_xref="EnsemblGenomes-Tr:CAB12266" /db_xref="GOA:P96615" /db_xref="InterPro:IPR005182" /db_xref="SubtiList:BG12086" /db_xref="UniProtKB/Swiss-Prot:P96615" /translation="MREQPKNQISPDGLKVWRLQEIIISAVCLLIVIAVAVLSYYFHW PYWISGVLGAVWLLGSIVTVFIIPKVRHKVWRYEVHEHEIDIQSGIFVVTRVIVPMVR VQHVDTSQGPLLKKYNLATVKISTAATVHSIPALEMEEADRLRDSISRLARVTDDDV* " gene 512814..513293 /gene="ydbS" /locus_tag="BSU_04590" /old_locus_tag="BSU04590" CDS 513283..514764 /gene="ydbT" /locus_tag="BSU_04600" /old_locus_tag="BSU04600" /experiment="publication(s) with functional evidences, PMID:16629676" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16629676; Product type ph: phenotype" /codon_start=1 /transl_table=11 /product="resistance to heterologous antibiotics" /protein_id="NP_388341.1" /db_xref="EnsemblGenomes-Gn:BSU04600" /db_xref="EnsemblGenomes-Tr:CAB12267" /db_xref="GOA:P96616" /db_xref="InterPro:IPR005182" /db_xref="InterPro:IPR014529" /db_xref="SubtiList:BG12087" /db_xref="UniProtKB/Swiss-Prot:P96616" /translation="MMSEPKRLHPVAVILNLCHTIIQTIKNIILPFFFVYIVNSNHTV RFYGAIALGVLFIWLVAASIIKWRRFTYRIEDDEFRIEEGLFVTKKRYISIDRIQTMN TSAGLVQQIFKLVKLQIETAGGGKEAEAVLSAISVEEAERIKEAVFKKKAQRRENELD EERLEAEEELDPSVEVQEHYRMNAKELLMAASTSGGIGVIISAVFALISQLDEVLPMD WLFDKFSFLQHASIGIYAVLIFIGLFIAWIFSIAGMMFRYANFQIIKKEQELVISRGI IEKHQVTIPLRKIQAIKIKENIIRQLFGFVTVSIVSAGGGDREKEEGALTILFPMIHK KKLPHMLRTFTPEYTLEENCRRLPRRALKRYLFRSVIFSLFLIIPLCIFFQPWGYLSV ILLPIELLFGYLAYKEAAWTINGDRLQLTSRFIGRTTAIVLKKRMQVCKFSQSYFQKK GRLYTISTSVKSSSHMEELTVRDVGEEDAAFILKWYSYEKADG*" gene 513283..514764 /gene="ydbT" /locus_tag="BSU_04600" /old_locus_tag="BSU04600" downshifts 514734 /Source="Nicolas_upshifts" /id="D220" /incds=0 /nref=6 /ntot=162 /MaxReadThrough="4.90913" /MaxDrop="3.0931" /score="48.2239319" /energy="-17.1" /TU="U363" /idTUdmin="U364" /TUdmin="-638" /isTUend="FALSE" S_feature 514779..515106 /Source="Nicolas_S_feature" /locus_tag="new_514779_515106" /HighExp="Salt, T0.30H, G135, T1.0H, T1.30H, G150, G180, Oxctl, T-0.40H, aero" /AntisenseName="ydcA" /AntisenseCor="-0.25636523135066602" /AntisenseRegPval="-4.7" /CDS_PredictionProba="NA" /TUshortSig="SigWXY" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S160" downshifts complement(514788) /Source="Nicolas_upshifts" /id="D221" /incds=0 /nref=1 /ntot=66 /MaxReadThrough="0.258529999999999" /MaxDrop="3.15455" /score="-3.74867023" /energy="-8.8" /TU="NA" /idTUdmin="U365" /TUdmin=220 /isTUend="FALSE" CDS complement(515016..515615) /gene="ydcA" /locus_tag="BSU_04610" /old_locus_tag="BSU04610" /EC_number="3.4.21.-" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15616571, 15849754, 16850406; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative rhomboid protease" /protein_id="NP_388342.1" /db_xref="EnsemblGenomes-Gn:BSU04610" /db_xref="EnsemblGenomes-Tr:CAB12268" /db_xref="GOA:P96617" /db_xref="InterPro:IPR022764" /db_xref="InterPro:IPR035952" /db_xref="SubtiList:BG12088" /db_xref="UniProtKB/Swiss-Prot:P96617" /translation="MFIRTENFQTFIRLYPVVTFILALQAVLWLFFSLPAHSVVLWRD TVTGYNLGVANGEWWRLITPILLHAGFTHLLFNSMSIFLFAPALERMLGKARFLLVYA GSGIIGNIGTYVTEPLDYVHVGASGAIFGLFGVYLFMVLFRNELIGQEHSKMIITLLA FAVLMSFINSNINMMAHLFGLCGGFLLSFLCVQKKERRY*" gene complement(515016..515615) /gene="ydcA" /locus_tag="BSU_04610" /old_locus_tag="BSU04610" promotor_-35 515076..515081 /Source="Nicolas_upshift_promotors" /id="U364" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.988011988011988" /psig=1 /xcortree=2751 /SigmaFactorBS="aaaacgaaagaagaaacccgccgcatagTCCAAAcaaatggg ccatCATGTTAATATTGGAGTTGAtaaacgacatgagaacggcaaatgcgagcagtgt g" /listShort="S161" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 515094..515113 /Source="Nicolas_upshift_promotors" /id="U364" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.988011988011988" /psig=1 /xcortree=2751 /SigmaFactorBS="aaaacgaaagaagaaacccgccgcatagTCCAAAcaaatggg ccatCATGTTAATATTGGAGTTGAtaaacgacatgagaacggcaaatgcgagcagtgt g" /listShort="S161" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 515108..515709 /Source="Nicolas_S_feature" /locus_tag="new_515108_515709" /HighExp="Salt, G135, G150, T0.30H, G180, T1.0H, T1.30H, H2O2, Paraq, Oxctl" /AntisenseName="ydcA" /AntisenseCor="-0.11975373672841701" /AntisenseRegPval="-1.3" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigWXY" /TUshortPSig="1, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S161" upshifts 515108 /Source="Nicolas_upshifts" /id="U364" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.988011988011988" /psig=1 /xcortree=2751 /SigmaFactorBS="aaaacgaaagaagaaacccgccgcatagTCCAAAcaaatggg ccatCATGTTAATATTGGAGTTGAtaaacgacatgagaacggcaaatgcgagcagtgt g" /listShort="S161" /GFF_Attribute="listLong" misc_feature complement(515639..515658) /Source="Nicolas_upshift_promotors" /id="U365" /multdbtbs="SigE" /comp="M4" /sig="SigA" /pcomp="0.879120879120879" /psig="0.907092907092907" /xcortree=1402 /SigmaFactorBS="tgtatgataacctcctttgcgtacgtactatttaaatggttt gtctcataaaCGTGTTACTATAGATATACCaaaatgaagaaaaggggctcggaatgtt t" /listShort="ydcA" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(515650) /Source="Nicolas_upshifts" /id="U365" /multdbtbs="SigE" /comp="M4" /sig="SigA" /pcomp="0.879120879120879" /psig="0.907092907092907" /xcortree=1402 /SigmaFactorBS="tgtatgataacctcctttgcgtacgtactatttaaatggttt gtctcataaaCGTGTTACTATAGATATACCaaaatgaagaaaaggggctcggaatgtt t" /listShort="ydcA" /GFF_Attribute="listLong" CDS 515710..516075 /gene="acpS" /locus_tag="BSU_04620" /old_locus_tag="BSU04620" /EC_number="2.7.8.7" /function="16.13: Shape" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1c: Function from experimental evidences in the studied genus; PubMedId: 11489886, 11525165, 11867633, 12682299, 12926246, 15955059, 16597923; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="holo-acyl carrier protein synthase (phosphopantetheinyl transferase)" /protein_id="NP_388343.1" /db_xref="EnsemblGenomes-Gn:BSU04620" /db_xref="EnsemblGenomes-Tr:CAB12269" /db_xref="GOA:P96618" /db_xref="InterPro:IPR002582" /db_xref="InterPro:IPR004568" /db_xref="InterPro:IPR008278" /db_xref="InterPro:IPR037143" /db_xref="PDB:1F7L" /db_xref="PDB:1F7T" /db_xref="PDB:1F80" /db_xref="SubtiList:BG12089" /db_xref="UniProtKB/Swiss-Prot:P96618" /translation="MIYGIGLDITELKRIASMAGRQKRFAERILTRSELDQYYELSEK RKNEFLAGRFAAKEAFSKAFGTGIGRQLSFQDIEIRKDQNGKPYIICTKLSQAAVHVS ITHTKEYAAAQVVIERLSS*" gene 515710..516075 /gene="acpS" /locus_tag="BSU_04620" /old_locus_tag="BSU04620" promotor_-35 516078..516083 /Source="Nicolas_upshift_promotors" /id="U366" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=976 /SigmaFactorBS="tgccgcgcaggttgtgattgaaaggttgtcaagctagtcTGC ATAttagggaaaccccacTCATATATTTGATAGTGCAttaagggagacaagttgtttg a" /listShort="S162, ydcC, alrA" /listLong="endB, ndoA" /label="promotor_-35" S_feature 516099..516240 /Source="Nicolas_S_feature" /locus_tag="new_516099_516240" /HighExp="S3, S4, BT, LoTm, S5, T5.0H, M9-stat, S7, T4.0H, T3.30H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigEF, SigWXY" /TUshortPSig="1, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S162" promotor_-10 516099..516117 /Source="Nicolas_upshift_promotors" /id="U366" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=976 /SigmaFactorBS="tgccgcgcaggttgtgattgaaaggttgtcaagctagtcTGC ATAttagggaaaccccacTCATATATTTGATAGTGCAttaagggagacaagttgtttg a" /listShort="S162, ydcC, alrA" /listLong="endB, ndoA" /label="promotor_-10" upshifts 516099 /Source="Nicolas_upshifts" /id="U366" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=976 /SigmaFactorBS="tgccgcgcaggttgtgattgaaaggttgtcaagctagtcTGC ATAttagggaaaccccacTCATATATTTGATAGTGCAttaagggagacaagttgtttg a" /listShort="S162, ydcC, alrA" /listLong="endB, ndoA" CDS 516241..517257 /gene="ydcC" /locus_tag="BSU_04630" /old_locus_tag="BSU04630" /function="16.5: Explore" /function="16.13: Shape" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 14523133; Product type lp: lipoprotein" /codon_start=1 /transl_table=11 /product="putative lipoprotein" /protein_id="NP_388344.2" /db_xref="EnsemblGenomes-Gn:BSU04630" /db_xref="EnsemblGenomes-Tr:CAB12270" /db_xref="GOA:P96619" /db_xref="InterPro:IPR029046" /db_xref="SubtiList:BG12090" /db_xref="UniProtKB/Swiss-Prot:P96619" /translation="MKKVRKSFVLLLTGLLAVLILSACGQKTQQDIVAGLDEKAKEYT SYKAKAKMTIETGSEPQVYNVEIWHKKPSLYRVYLENPKKDQNQVILRNENGVFVLTP SLNKSFRFQSDWPNNSSQVYLFESLVKDVQNDSDAVFTAKEKKYVFETKTNYQHNKML PTQEITFNKKDMSPSSVKVMDTDRKVMVKVEFSSFEFNKQFDKESFDEKKNMTLSQMD VATSAKPSDTFAVKTPLELPLGVKLLEEKDISTEDGKRIIMTYGGEKSFTLIQEKAQI AKASSSVTLNGEPVNLGYTIGALSDASLSWTYDGVDYLLSSKDLSKEEMVTVAKSMQG QSSK*" gene 516241..517257 /gene="ydcC" /locus_tag="BSU_04630" /old_locus_tag="BSU04630" downshifts 517242 /Source="Nicolas_upshifts" /id="D222" /incds=0 /nref=193 /ntot=256 /MaxReadThrough="3.39815" /MaxDrop="6.13946" /score="22.0391647" /energy="-9.5" /TU="U366" /idTUdmin="U363" /TUdmin=0 /isTUend="TRUE" promotor_-35 517302..517309 /Source="Nicolas_upshift_promotors" /id="U367" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.652347652347652" /psig=1 /xcortree=1877 /SigmaFactorBS="aaacatgatttggcctttttttcgttagacatCGTTTCCCtt tagcctttaatTTTAGTATGATATGTAAATGatattgaataaaagctaggaagtgtcg t" /listShort="alrA, endB, ndoA, rsbRA, rsbS, rsbT, rsbU, rsbV, rsbW, sigB, rsbX" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 517323..517342 /Source="Nicolas_upshift_promotors" /id="U367" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.652347652347652" /psig=1 /xcortree=1877 /SigmaFactorBS="aaacatgatttggcctttttttcgttagacatCGTTTCCCtt tagcctttaatTTTAGTATGATATGTAAATGatattgaataaaagctaggaagtgtcg t" /listShort="alrA, endB, ndoA, rsbRA, rsbS, rsbT, rsbU, rsbV, rsbW, sigB, rsbX" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 517330 /Source="Nicolas_upshifts" /id="U367" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.652347652347652" /psig=1 /xcortree=1877 /SigmaFactorBS="aaacatgatttggcctttttttcgttagacatCGTTTCCCtt tagcctttaatTTTAGTATGATATGTAAATGatattgaataaaagctaggaagtgtcg t" /listShort="alrA, endB, ndoA, rsbRA, rsbS, rsbT, rsbU, rsbV, rsbW, sigB, rsbX" /GFF_Attribute="listLong" CDS 517372..518541 /gene="alrA" /locus_tag="BSU_04640" /old_locus_tag="BSU04640" /EC_number="5.1.1.1" /function="16.2: Construct biomass (Anabolism)" /function="16.13: Shape" /function="16.8: Protect" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1c: Function from experimental evidences in the studied genus; PubMedId: 2835089, 12682299, 15043879, 18399999, 25227915; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="D-alanine racemase" /protein_id="NP_388345.1" /db_xref="EnsemblGenomes-Gn:BSU04640" /db_xref="EnsemblGenomes-Tr:CAB12271" /db_xref="GOA:P10725" /db_xref="InterPro:IPR000821" /db_xref="InterPro:IPR001608" /db_xref="InterPro:IPR009006" /db_xref="InterPro:IPR011079" /db_xref="InterPro:IPR020622" /db_xref="InterPro:IPR029066" /db_xref="SubtiList:BG10950" /db_xref="UniProtKB/Swiss-Prot:P10725" /translation="MSTKPFYRDTWAEIDLSAIKENVSNMKKHIGEHVHLMAVVKANA YGHGDAETAKAALDAGASCLAVAILDEAISLRKKGLKAPILVLGAVPPEYVAIAAEYD VTLTGYSVEWLQEAARHTKKGSLHFHLKVDTGMNRLGVKTEEEVQNVMAILDRNPRLK CKGVFTHFATADEKERGYFLMQFERFKELIAPLPLKNLMVHCANSAAGLRLKKGFFNA VRFGIGMYGLRPSADMSDEIPFQLRPAFTLHSTLSHVKLIRKGESVSYGAEYTAEKDT WIGTVPVGYADGWLRKLKGTDILVKGKRLKIAGRICMDQFMVELDQEYPPGTKVTLIG RQGDEYISMDEIAGRLETINYEVACTISSRVPRMFLENGSIMEVRNPLLQVNISN*" gene 517372..518541 /gene="alrA" /locus_tag="BSU_04640" /old_locus_tag="BSU04640" promotor_-35 518470..518475 /Source="Nicolas_upshift_promotors" /id="U368" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.93906093906094" /psig="0.93906093906094" /xcortree=1177 /SigmaFactorBS="tgaggtggcctgtacaataagttcccgtgttcccCGTATGtt tttggaaaatggGAGTATAATGGAAGTAAGAaatcctttattgcaggtaaatataagc a" /listShort="endB, ndoA, rsbRA, rsbS, rsbT, rsbU, rsbV, rsbW, sigB, rsbX" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 518490..518508 /Source="Nicolas_upshift_promotors" /id="U368" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.93906093906094" /psig="0.93906093906094" /xcortree=1177 /SigmaFactorBS="tgaggtggcctgtacaataagttcccgtgttcccCGTATGtt tttggaaaatggGAGTATAATGGAAGTAAGAaatcctttattgcaggtaaatataagc a" /listShort="endB, ndoA, rsbRA, rsbS, rsbT, rsbU, rsbV, rsbW, sigB, rsbX" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 518496 /Source="Nicolas_upshifts" /id="U368" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.93906093906094" /psig="0.93906093906094" /xcortree=1177 /SigmaFactorBS="tgaggtggcctgtacaataagttcccgtgttcccCGTATGtt tttggaaaatggGAGTATAATGGAAGTAAGAaatcctttattgcaggtaaatataagc a" /listShort="endB, ndoA, rsbRA, rsbS, rsbT, rsbU, rsbV, rsbW, sigB, rsbX" /GFF_Attribute="listLong" promotor_-35 518571..518574 /Source="Nicolas_upshift_promotors" /id="U369" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.527472527472527" /psig=1 /xcortree=2132 /SigmaFactorBS="taagcaattaacttacctaaatggagaattcataaaacagCT TTgcttgaagagtgaatAATGGTATCATTATCACTGGatggataaaagagtcgtatcc g" /listShort="endB, ndoA, rsbRA, rsbS, rsbT, rsbU, rsbV, rsbW, sigB, rsbX" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 518590..518609 /Source="Nicolas_upshift_promotors" /id="U369" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.527472527472527" /psig=1 /xcortree=2132 /SigmaFactorBS="taagcaattaacttacctaaatggagaattcataaaacagCT TTgcttgaagagtgaatAATGGTATCATTATCACTGGatggataaaagagtcgtatcc g" /listShort="endB, ndoA, rsbRA, rsbS, rsbT, rsbU, rsbV, rsbW, sigB, rsbX" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 518591 /Source="Nicolas_upshifts" /id="U369" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.527472527472527" /psig=1 /xcortree=2132 /SigmaFactorBS="taagcaattaacttacctaaatggagaattcataaaacagCT TTgcttgaagagtgaatAATGGTATCATTATCACTGGatggataaaagagtcgtatcc g" /listShort="endB, ndoA, rsbRA, rsbS, rsbT, rsbU, rsbV, rsbW, sigB, rsbX" /GFF_Attribute="listLong" CDS 518657..518938 /gene="ndoAI" /locus_tag="BSU_04650" /old_locus_tag="BSU04650" /function="16.3: Control" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:15882409, 21763692, 22720735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15882409, 21763692, 22720735; Product type r: regulator" /codon_start=1 /transl_table=11 /product="antitoxin EndoAI" /protein_id="NP_388346.1" /db_xref="EnsemblGenomes-Gn:BSU04650" /db_xref="EnsemblGenomes-Tr:CAB12272" /db_xref="GOA:P96621" /db_xref="InterPro:IPR002145" /db_xref="InterPro:IPR010985" /db_xref="InterPro:IPR013321" /db_xref="PDB:4ME7" /db_xref="SubtiList:BG12091" /db_xref="UniProtKB/Swiss-Prot:P96621" /translation="MSESSARTEMKISLPENLVAELDGVAMREKRSRNELISQAVRAY VSERTTRHNRDLMRRGYMEMAKINLNISSEAHFAECEAETTVERLVSGG*" gene 518657..518938 /gene="ndoAI" /locus_tag="BSU_04650" /old_locus_tag="BSU04650" CDS 518943..519293 /gene="ndoA" /locus_tag="BSU_04660" /old_locus_tag="BSU04660" /function="16.5: Explore" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:15882409, 21763692, 21897862, 22720735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15882409, 21763692, 21897862, 22720735; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="endoribonuclease toxin" /protein_id="NP_388347.1" /db_xref="EnsemblGenomes-Gn:BSU04660" /db_xref="EnsemblGenomes-Tr:CAB12273" /db_xref="GOA:P96622" /db_xref="InterPro:IPR003477" /db_xref="InterPro:IPR011067" /db_xref="PDB:1NE8" /db_xref="PDB:4MDX" /db_xref="PDB:4ME7" /db_xref="SubtiList:BG12092" /db_xref="UniProtKB/Swiss-Prot:P96622" /translation="MIVKRGDVYFADLSPVVGSEQGGVRPVLVIQNDIGNRFSPTAIV AAITAQIQKAKLPTHVEIDAKRYGFERDSVILLEQIRTIDKQRLTDKITHLDDEMMDK VDEALQISLALIDF*" gene 518943..519293 /gene="ndoA" /locus_tag="BSU_04660" /old_locus_tag="BSU04660" S_feature complement(519083..519559) /Source="Nicolas_S_feature" /locus_tag="new_519083_519559_c" /HighExp="Etha, Gly, Sw, S8, C30, S6, LBGstat, T0.30H, S7, Salt" /AntisenseName="ndoA" /AntisenseCor="-0.36117231948253697" /AntisenseRegPval="-9" /CDS_PredictionProba="NA" /TUshortSig="SigD, SigB, SigK" /TUshortPSig="1, 1, 0.973" /TUlongSig="NA" /TUlongPSig="NA" /label="S163" downshifts complement(519126) /Source="Nicolas_upshifts" /id="D223" /incds=1 /nref=6 /ntot=171 /MaxReadThrough="3.51096" /MaxDrop="3.79912" /score="-8.86444162" /energy="-10.2" /TU="U372" /idTUdmin="U371" /TUdmin="-4" /isTUend="TRUE" downshifts 519273 /Source="Nicolas_upshifts" /id="D224" /incds=0 /nref=143 /ntot=254 /MaxReadThrough="5.57908" /MaxDrop="5.74865" /score="29.7721113" /energy="-8.9" /TU="U367,U368,U369" /idTUdmin="U366" /TUdmin=799 /isTUend="FALSE" promotor_-35 519327..519334 /Source="Nicolas_upshift_promotors" /id="U370" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.772227772227772" /psig="0.999000999001" /xcortree=1992 /SigmaFactorBS="atatttgcaggttgctcaaatagagcaacttTTTTTGTTttc aaaaaacataAACGATATAATAGTGAAATAacgaaaaaatatgttgttttttattggg a" /listShort="rsbRA, rsbS, rsbT, rsbU, rsbV, rsbW, sigB, rsbX" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 519348..519367 /Source="Nicolas_upshift_promotors" /id="U370" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.772227772227772" /psig="0.999000999001" /xcortree=1992 /SigmaFactorBS="atatttgcaggttgctcaaatagagcaacttTTTTTGTTttc aaaaaacataAACGATATAATAGTGAAATAacgaaaaaatatgttgttttttattggg a" /listShort="rsbRA, rsbS, rsbT, rsbU, rsbV, rsbW, sigB, rsbX" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 519356 /Source="Nicolas_upshifts" /id="U370" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.772227772227772" /psig="0.999000999001" /xcortree=1992 /SigmaFactorBS="atatttgcaggttgctcaaatagagcaacttTTTTTGTTttc aaaaaacataAACGATATAATAGTGAAATAacgaaaaaatatgttgttttttattggg a" /listShort="rsbRA, rsbS, rsbT, rsbU, rsbV, rsbW, sigB, rsbX" /GFF_Attribute="listLong" CDS 519408..520232 /gene="rsbRA" /locus_tag="BSU_04670" /old_locus_tag="BSU04670" /function="16.8: Protect" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:15312768, 15583165, 16963570, 17158665, 11157946, 20019076, 21362065, 22287516, 23320651, 28271471" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15312768, 15583165, 16963570, 17158665, 11157946, 20019076, 21362065, 22287516, 23320651, 28271471; Product type f: factor" /codon_start=1 /transl_table=11 /product="component of the anxiosome (stressosome); positive regulation of sigma(B) activity in response to salt and heat stress" /protein_id="NP_388348.1" /db_xref="EnsemblGenomes-Gn:BSU04670" /db_xref="EnsemblGenomes-Tr:CAB12274" /db_xref="InterPro:IPR002645" /db_xref="InterPro:IPR014792" /db_xref="InterPro:IPR036513" /db_xref="PDB:2BNL" /db_xref="SubtiList:BG11090" /db_xref="UniProtKB/Swiss-Prot:P42409" /translation="MMSNQTVYQFIAENQNELLQLWTDTLKELSEQESYQLTDQVYEN ISKEYIDILLLSVKDENAAESQISELALRAVQIGLSMKFLATALAEFWKRLYTKMNDK RLPDQESTELIWQIDRFFSPINTEIFNQYSISWEKTVSLQKIALQELSAPLIPVFENI TVMPLVGTIDTERAKRIMENLLNGVVKHRSQVVLIDITGVPVVDTMVAHHIIQASEAV RLVGAKCLLAGIRPEIAQTIVNLGIDLSQVITKNTLQKGIQTALEMTDRKIVSLGE*" gene 519408..520232 /gene="rsbRA" /locus_tag="BSU_04670" /old_locus_tag="BSU04670" promotor_-10 complement(519542..519560) /Source="Nicolas_upshift_promotors" /id="U371" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2828 /SigmaFactorBS="gccagttcgctgatttggctttcagcagcattttcgtcCTTA ACAGacagcagcagaatGTCGATATATTCTTTAGATatattttcatacacttggtcag t" /listShort="S163" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(519559) /Source="Nicolas_upshifts" /id="U371" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2828 /SigmaFactorBS="gccagttcgctgatttggctttcagcagcattttcgtcCTTA ACAGacagcagcagaatGTCGATATATTCTTTAGATatattttcatacacttggtcag t" /listShort="S163" /GFF_Attribute="listLong" S_feature complement(519561..520160) /Source="Nicolas_S_feature" /locus_tag="new_519561_520160_c" /HighExp="Etha, Sw, Gly, S6, S8, S7, B60, Salt, BT, M9-stat" /AntisenseName="rsbRA" /AntisenseCor="-0.53924606340364201" /AntisenseRegPval="-21" /CDS_PredictionProba="NA" /TUshortSig="SigB, SigK" /TUshortPSig="1, 0.973" /TUlongSig="NA" /TUlongPSig="NA" /label="S164" promotor_-35 complement(519574..519581) /Source="Nicolas_upshift_promotors" /id="U371" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2828 /SigmaFactorBS="gccagttcgctgatttggctttcagcagcattttcgtcCTTA ACAGacagcagcagaatGTCGATATATTCTTTAGATatattttcatacacttggtcag t" /listShort="S163" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(520149..520167) /Source="Nicolas_upshift_promotors" /id="U372" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=202 /SigmaFactorBS="tgaaacgatttttcgatccgtcatttccaatgcTGTTTGAat tcctttttgcaGGGTATTCTTAGTTATAACttgggataaatcaatccccaggttgacg a" /listShort="S164, S163" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(520160) /Source="Nicolas_upshifts" /id="U372" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=202 /SigmaFactorBS="tgaaacgatttttcgatccgtcatttccaatgcTGTTTGAat tcctttttgcaGGGTATTCTTAGTTATAACttgggataaatcaatccccaggttgacg a" /listShort="S164, S163" /GFF_Attribute="listLong" S_feature complement(520162..520750) /Source="Nicolas_S_feature" /locus_tag="new_520162_520750_c" /HighExp="S6, S8, S7, BT, C30, S5, G135, C90, Gly, Fru" /AntisenseName="rsbS" /AntisenseCor="-0.57706416777859804" /AntisenseRegPval="-24.6" /CDS_PredictionProba="NA" /TUshortSig="SigK" /TUshortPSig="0.973" /TUlongSig="NA" /TUlongPSig="NA" /label="S165" promotor_-35 complement(520181..520187) /Source="Nicolas_upshift_promotors" /id="U372" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=202 /SigmaFactorBS="tgaaacgatttttcgatccgtcatttccaatgcTGTTTGAat tcctttttgcaGGGTATTCTTAGTTATAACttgggataaatcaatccccaggttgacg a" /listShort="S164, S163" /GFF_Attribute="listLong" /label="promotor_-35" CDS 520237..520602 /gene="rsbS" /locus_tag="BSU_04680" /old_locus_tag="BSU04680" /function="16.3: Control" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:15583165, 16963570, 17158665, 11157946, 23320651, 28271471" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15583165, 16963570, 17158665, 11157946, 23320651, 28271471; Product type f : factor" /codon_start=1 /transl_table=11 /product="antagonist of RsbT" /protein_id="NP_388349.1" /db_xref="EnsemblGenomes-Gn:BSU04680" /db_xref="EnsemblGenomes-Tr:CAB12275" /db_xref="GOA:P42410" /db_xref="InterPro:IPR002645" /db_xref="InterPro:IPR036513" /db_xref="SubtiList:BG11091" /db_xref="UniProtKB/Swiss-Prot:P42410" /translation="MRHPKIPILKLYNCLLVSIQWELDDQTALTFQEDLLNKIYETGA NGVVIDLTSVDMIDSFIAKVLGDVITMSKLMGAKVVLTGIQPAVAVTLIELGIALEEI ETALDLEQGLETLKRELGE*" gene 520237..520602 /gene="rsbS" /locus_tag="BSU_04680" /old_locus_tag="BSU04680" CDS 520606..521007 /gene="rsbT" /locus_tag="BSU_04690" /old_locus_tag="BSU04690" /EC_number="2.7.11.1" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:15583165, 16963570, 17158665, 11157946, 20019076, 20558511, 21362065, 21979936, 23320651" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15583165, 16963570, 17158665, 11157946, 20019076, 20558511, 21362065, 21979936, 23320651; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="switch protein/serine-threonine kinase; controlsthe activity of the anxiosome (stressosome)" /protein_id="NP_388350.1" /db_xref="EnsemblGenomes-Gn:BSU04690" /db_xref="EnsemblGenomes-Tr:CAB12276" /db_xref="GOA:P42411" /db_xref="InterPro:IPR003594" /db_xref="InterPro:IPR036890" /db_xref="SubtiList:BG11092" /db_xref="UniProtKB/Swiss-Prot:P42411" /translation="MNDQSCVRIMTEWDIVAARQLGRNVAKELGFGTVDQARITTAIS ELARNIYLYAGKGQIGIEQVADRGKKGLKIIAEDQGPGIPDIRKVMEDGFSTSGGLGA GLPGVKRLMDEFSLNSVAGEGTEIQAIKWLR*" gene 520606..521007 /gene="rsbT" /locus_tag="BSU_04690" /old_locus_tag="BSU04690" promotor_-10 complement(520748..520767) /Source="Nicolas_upshift_promotors" /id="U373" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.973026973026973" /psig="0.973026973026973" /xcortree=1334 /SigmaFactorBS="ttttcaggcctttttttcctctgtctgcgacctgtTCAATTC CAAtctgccctttgccGGCATATAAATAAATATTCCtggctaattctgaaatagccgt t" /listShort="S165, S164, S163" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(520765) /Source="Nicolas_upshifts" /id="U373" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.973026973026973" /psig="0.973026973026973" /xcortree=1334 /SigmaFactorBS="ttttcaggcctttttttcctctgtctgcgacctgtTCAATTC CAAtctgccctttgccGGCATATAAATAAATATTCCtggctaattctgaaatagccgt t" /listShort="S165, S164, S163" /GFF_Attribute="listLong" promotor_-35 complement(520781..520790) /Source="Nicolas_upshift_promotors" /id="U373" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.973026973026973" /psig="0.973026973026973" /xcortree=1334 /SigmaFactorBS="ttttcaggcctttttttcctctgtctgcgacctgtTCAATTC CAAtctgccctttgccGGCATATAAATAAATATTCCtggctaattctgaaatagccgt t" /listShort="S165, S164, S163" /GFF_Attribute="listLong" /label="promotor_-35" CDS 521019..522026 /gene="rsbU" /locus_tag="BSU_04700" /old_locus_tag="BSU04700" /EC_number="3.1.3.3" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:15583165, 16963570, 17158665, 17303566, 21979936, 28461450" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15583165, 16963570, 17158665, 17303566, 21979936, 28461450; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="protein serine phosphatase; controls the activity of the anxiosome (stressosome)" /protein_id="NP_388351.1" /db_xref="EnsemblGenomes-Gn:BSU04700" /db_xref="EnsemblGenomes-Tr:CAB12277" /db_xref="GOA:P40399" /db_xref="InterPro:IPR001932" /db_xref="InterPro:IPR014787" /db_xref="InterPro:IPR017944" /db_xref="InterPro:IPR036457" /db_xref="PDB:1W53" /db_xref="PDB:2J6Y" /db_xref="PDB:2J6Z" /db_xref="PDB:2J70" /db_xref="SubtiList:BG11057" /db_xref="UniProtKB/Swiss-Prot:P40399" /translation="MDFREVIEQRYHQLLSRYIAELTETSLYQAQKFSRKTIEHQIPP EEIISIHRKVLKELYPSLPEDVFHSLDFLIEVMIGYGMAYQEHQTLRGIQQEIKSEIE IAANVQQTLLGTKVPQEEALDIGAISVPAKQMSGDYYHFVKDKESINIAIADVIGKGI PAALCMSMIKYAMDSLPETGIHPSQVLKNLNRVVEQNVDASMFITMFYANYNMDKHQF TYASAGHEPGFYYSQKDNTFYDLEAKGLVLGISQDYDYKQFDQHLEKGDMIVLFSDGV TECRTENGFLERPDLQKLIEEHMCSSAQEMVKNIYDSLLKLQDFQLHDDFTLIVLRRK V*" gene 521019..522026 /gene="rsbU" /locus_tag="BSU_04700" /old_locus_tag="BSU04700" promotor_-35 522020..522026 /Source="Nicolas_upshift_promotors" /id="U374" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=260 /SigmaFactorBS="cgatgattttacgttaattgttttgcggagaaaGGTTTAAcg tctgtcagacgaGGGTATAAAGCAACTAGTGatttgaaggaaaatttgaggtgatacg a" /listShort="rsbV, rsbW, sigB, rsbX" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 522041..522059 /Source="Nicolas_upshift_promotors" /id="U374" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=260 /SigmaFactorBS="cgatgattttacgttaattgttttgcggagaaaGGTTTAAcg tctgtcagacgaGGGTATAAAGCAACTAGTGatttgaaggaaaatttgaggtgatacg a" /listShort="rsbV, rsbW, sigB, rsbX" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 522047 /Source="Nicolas_upshifts" /id="U374" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=260 /SigmaFactorBS="cgatgattttacgttaattgttttgcggagaaaGGTTTAAcg tctgtcagacgaGGGTATAAAGCAACTAGTGatttgaaggaaaatttgaggtgatacg a" /listShort="rsbV, rsbW, sigB, rsbX" /GFF_Attribute="listLong" CDS 522088..522417 /gene="rsbV" /locus_tag="BSU_04710" /old_locus_tag="BSU04710" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:15342585, 15583165, 16077134, 16885458, 20454630, 21979936, 27977677" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15342585, 15583165, 16077134, 16885458, 20454630, 21979936, 27977677; Product type f: factor" /codon_start=1 /transl_table=11 /product="anti-anti-sigma factor (antagonist of RsbW)" /protein_id="NP_388352.1" /db_xref="EnsemblGenomes-Gn:BSU04710" /db_xref="EnsemblGenomes-Tr:CAB12278" /db_xref="GOA:P17903" /db_xref="InterPro:IPR002645" /db_xref="InterPro:IPR003658" /db_xref="InterPro:IPR036513" /db_xref="SubtiList:BG10733" /db_xref="UniProtKB/Swiss-Prot:P17903" /translation="MNINVDVKQNENDIQVNIAGEIDVYSAPVLREKLVPLAEQGADL RICLKDVSYMDSTGLGVFVGTFKMVKKQGGSLKLENLSERLIRLFDITGLKDIIDISA KSEGGVQ*" gene 522088..522417 /gene="rsbV" /locus_tag="BSU_04710" /old_locus_tag="BSU04710" CDS 522414..522896 /gene="rsbW" /locus_tag="BSU_04720" /old_locus_tag="BSU04720" /EC_number="2.7.11.1" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:15342585, 15583165, 16077134, 16885458, 21979936, 27977677" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15342585, 15583165, 16077134, 16885458, 21979936, 27977677; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="switch protein/serine kinase and anti-sigma factor (inhibitory sigma-B binding protein)" /protein_id="NP_388353.1" /db_xref="EnsemblGenomes-Gn:BSU04720" /db_xref="EnsemblGenomes-Tr:CAB12279" /db_xref="GOA:P17904" /db_xref="InterPro:IPR003594" /db_xref="InterPro:IPR010193" /db_xref="InterPro:IPR036890" /db_xref="SubtiList:BG10734" /db_xref="UniProtKB/Swiss-Prot:P17904" /translation="MKNNADYIEMKVPAQPEYVGIIRLTLSGVASRMGYTYDEIEDLK IAVSEACTNAVQHAYKEDKNGEVSIRFGVFEDRLEVIVADEGDSFDFDQKQQDLGPYT PSHTVDQLSEGGLGLYLMETLMDEVRVQNHSGVTVAMTKYLNGERVDHDTTIKNYETN *" gene 522414..522896 /gene="rsbW" /locus_tag="BSU_04720" /old_locus_tag="BSU04720" CDS 522862..523650 /gene="sigB" /locus_tag="BSU_04730" /old_locus_tag="BSU04730" /function="16.3: Control" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:15312768, 15805528, 16077134, 16267279, 16321960, 17158665, 28271471" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15312768, 15805528, 16077134, 16267279, 16321960, 17158665, 28271471; Product type r: regulator" /codon_start=1 /transl_table=11 /product="RNA polymerase sigma-37 factor (sigma(B))" /protein_id="NP_388354.2" /db_xref="EnsemblGenomes-Gn:BSU04730" /db_xref="EnsemblGenomes-Tr:CAB12280" /db_xref="GOA:P06574" /db_xref="InterPro:IPR000943" /db_xref="InterPro:IPR007624" /db_xref="InterPro:IPR007627" /db_xref="InterPro:IPR007630" /db_xref="InterPro:IPR013324" /db_xref="InterPro:IPR013325" /db_xref="InterPro:IPR014284" /db_xref="InterPro:IPR014288" /db_xref="InterPro:IPR014322" /db_xref="InterPro:IPR036388" /db_xref="SubtiList:BG10735" /db_xref="UniProtKB/Swiss-Prot:P06574" /translation="MTQPSKTTKLTKDEVDRLISDYQTKQDEQAQETLVRVYTNLVDM LAKKYSKGKSFHEDLRQVGMIGLLGAIKRYDPVVGKSFEAFAIPTIIGEIKRFLRDKT WSVHVPRRIKELGPRIKMAVDQLTTETQRSPKVEEIAEFLDVSEEEVLETMEMGKSYQ ALSVDHSIEADSDGSTVTILDIVGSQEDGYERVNQQLMLQSVLHVLSDREKQIIDLTY IQNKSQKETGDILGISQMHVSRLQRKAVKKLREALIEDPSMELM*" gene 522862..523650 /gene="sigB" /locus_tag="BSU_04730" /old_locus_tag="BSU04730" CDS 523650..524249 /gene="rsbX" /locus_tag="BSU_04740" /old_locus_tag="BSU04740" /EC_number="3.1.3.3" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:10671474, 12950928, 15466036, 9068644, 9658013, 21979936, 26057679" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10671474, 12950928, 15466036, 9068644, 9658013, 21979936, 26057679; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="serine phosphatase" /protein_id="NP_388355.1" /db_xref="EnsemblGenomes-Gn:BSU04740" /db_xref="EnsemblGenomes-Tr:CAB12281" /db_xref="GOA:P17906" /db_xref="InterPro:IPR001932" /db_xref="InterPro:IPR036457" /db_xref="PDB:3W40" /db_xref="PDB:3W41" /db_xref="PDB:3W42" /db_xref="PDB:3W43" /db_xref="PDB:3W44" /db_xref="PDB:3W45" /db_xref="SubtiList:BG10736" /db_xref="UniProtKB/Swiss-Prot:P17906" /translation="MIQVEENEHIQTLVYQLNKEGKSICGDSFFMKADDKELICAVAD GLGSGSLANESSAAIKDLVENYASEDVESIIERCNQAMKNKRGATASILKINFEQRQF TYCSVGNVRFILHSPSGESFYPLPISGYLSGKPQKYKTHTATYEKGSKFIIHTDGLNV PDIRSHLKKGQSVEEISNSLKMYTTSRKDDLTYILGQLS*" gene 523650..524249 /gene="rsbX" /locus_tag="BSU_04740" /old_locus_tag="BSU04740" downshifts 524235 /Source="Nicolas_upshifts" /id="D225" /incds=0 /nref=267 /ntot=278 /MaxReadThrough="2.46753" /MaxDrop="7.92167" /score="1.26147577" /energy="-6" /TU="NA" /idTUdmin="U369" /TUdmin="-3" /isTUend="TRUE" promotor_-35 524293..524299 /Source="Nicolas_upshift_promotors" /id="U375" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.427572427572428" /psig=1 /xcortree=2529 /SigmaFactorBS="gctggacatccggcttcttttttttgcGGTTGACtattaata agtgcgCTTATTATAATTAATAAGTGaacttatcattctgggagcttatgggatgtgg a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 524314..524333 /Source="Nicolas_upshift_promotors" /id="U375" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.427572427572428" /psig=1 /xcortree=2529 /SigmaFactorBS="gctggacatccggcttcttttttttgcGGTTGACtattaata agtgcgCTTATTATAATTAATAAGTGaacttatcattctgggagcttatgggatgtgg a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 524326 /Source="Nicolas_upshifts" /id="U375" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.427572427572428" /psig=1 /xcortree=2529 /SigmaFactorBS="gctggacatccggcttcttttttttgcGGTTGACtattaata agtgcgCTTATTATAATTAATAAGTGaacttatcattctgggagcttatgggatgtgg a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" CDS 524360..524476 /locus_tag="BSU_04745" /old_locus_tag="BSU04745" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_009513945.1" /translation="MWNYEYTAIADVDVGKPGTVIRKQKQWINGRRVLHQIL*" gene 524360..524476 /locus_tag="BSU_04745" /old_locus_tag="BSU04745" CDS 524492..524785 /gene="ydcF" /locus_tag="BSU_04750" /old_locus_tag="BSU04750" /function="18: Unknown function" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_388356.1" /db_xref="EnsemblGenomes-Gn:BSU04750" /db_xref="EnsemblGenomes-Tr:CAB12282" /db_xref="SubtiList:BG12093" /db_xref="UniProtKB/Swiss-Prot:P96623" /translation="MERKEHCFCKEKQFSYGLSMWRNIGRFLSWSTCPHSNVIMEFFH VLQKQKEDLCITYGIVLEGAEAKKWGEIIGTELSKDMPTAVSRLVHLYGGVIK*" gene 524492..524785 /gene="ydcF" /locus_tag="BSU_04750" /old_locus_tag="BSU04750" promotor_-35 524753..524761 /Source="Nicolas_upshift_promotors" /id="U376" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.65034965034965" /psig=1 /xcortree=2272 /SigmaFactorBS="agacatgccgacggctgtcagcaggCTTGTCCATctttacgg aggAGTGATAAAATGAACACAAAttactggatcggcgttgtgtcagagcaacatgtat t" /listShort="ydcG, ydcH" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 524773..524792 /Source="Nicolas_upshift_promotors" /id="U376" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.65034965034965" /psig=1 /xcortree=2272 /SigmaFactorBS="agacatgccgacggctgtcagcaggCTTGTCCATctttacgg aggAGTGATAAAATGAACACAAAttactggatcggcgttgtgtcagagcaacatgtat t" /listShort="ydcG, ydcH" /GFF_Attribute="listLong" /label="promotor_-10" CDS 524782..525222 /gene="ydcG" /locus_tag="BSU_04760" /old_locus_tag="BSU04760" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_388357.1" /db_xref="EnsemblGenomes-Gn:BSU04760" /db_xref="EnsemblGenomes-Tr:CAB12283" /db_xref="InterPro:IPR002740" /db_xref="InterPro:IPR015947" /db_xref="InterPro:IPR022996" /db_xref="SubtiList:BG12094" /db_xref="UniProtKB/Swiss-Prot:P96624" /translation="MNTNYWIGVVSEQHVLKGAAGGFAQLCHGKKAPLAKMKEGDWLI YYSPRDAYPDGKLLRSFTAIGKVKSGNIYPYQMAPNFIPYRLDIDYYPCHKIGFYDIK SKLEFVQETKHLGFLFRRGHFEISKKDFLTIAQAMGVNISGMAL*" gene 524782..525222 /gene="ydcG" /locus_tag="BSU_04760" /old_locus_tag="BSU04760" upshifts 524788 /Source="Nicolas_upshifts" /id="U376" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.65034965034965" /psig=1 /xcortree=2272 /SigmaFactorBS="agacatgccgacggctgtcagcaggCTTGTCCATctttacgg aggAGTGATAAAATGAACACAAAttactggatcggcgttgtgtcagagcaacatgtat t" /listShort="ydcG, ydcH" /GFF_Attribute="listLong" S_feature complement(525021..528076) /Source="Nicolas_S_feature" /locus_tag="new_525021_528076_c" /HighExp="S6, S8, S7, S5, B36, S4, B60, BT, Pyr, C30" /AntisenseName="ydcI" /AntisenseCor="-0.61304426345041496" /AntisenseRegPval="-28.4" /CDS_PredictionProba="0.40759499999999999" /TUshortSig="SigK" /TUshortPSig="0.994" /TUlongSig="NA" /TUlongPSig="NA" /label="S166" CDS 525206..525649 /gene="ydcH" /locus_tag="BSU_04770" /old_locus_tag="BSU04770" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 12088660; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative transcriptional regulator" /protein_id="NP_388358.1" /db_xref="EnsemblGenomes-Gn:BSU04770" /db_xref="EnsemblGenomes-Tr:CAB12284" /db_xref="GOA:P96625" /db_xref="InterPro:IPR000835" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG12095" /db_xref="UniProtKB/Swiss-Prot:P96625" /translation="MEWHSKFSGPNTSPGFLLWQATQSWQRKVGKALAEFDLTHVQFV LLTSCKYMIAHGETVTQKKLASFSQTNIMMVSEVVRTLEKKGFIERSKNPQDKREVLL SLTEIGGEKVTAALPIVEKIDQAFFAAAMKKENFLSGLQELLKHE*" gene 525206..525649 /gene="ydcH" /locus_tag="BSU_04770" /old_locus_tag="BSU04770" downshifts 525624 /Source="Nicolas_upshifts" /id="D226" /incds=0 /nref=11 /ntot=147 /MaxReadThrough="2.17786" /MaxDrop="3.86856" /score="21.3746204" /energy="-6.8" /TU="NA" /idTUdmin="U376" /TUdmin=0 /isTUend="TRUE" promotor_-35 525680..525681 /Source="Nicolas_upshift_promotors" /id="U377" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.712287712287712" /psig="0.997002997002997" /xcortree=1998 /SigmaFactorBS="gaaacatgagtaaagatacgggcagcgccagctgtctttttt tATgtgtttttttcggttTTTGATACACTAGAGAAAGAacgacaaaattggaggcttt g" /listShort="ydcI, S167, ydcK" /listLong="S168, trnS-Asn, trnS-Ser, trnS-Glu, trnS-Gln, trnS-Lys, trnS-Leu1, trnS-Leu2" /label="promotor_-35" promotor_-10 525697..525716 /Source="Nicolas_upshift_promotors" /id="U377" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.712287712287712" /psig="0.997002997002997" /xcortree=1998 /SigmaFactorBS="gaaacatgagtaaagatacgggcagcgccagctgtctttttt tATgtgtttttttcggttTTTGATACACTAGAGAAAGAacgacaaaattggaggcttt g" /listShort="ydcI, S167, ydcK" /listLong="S168, trnS-Asn, trnS-Ser, trnS-Glu, trnS-Gln, trnS-Lys, trnS-Leu1, trnS-Leu2" /label="promotor_-10" upshifts 525697 /Source="Nicolas_upshifts" /id="U377" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.712287712287712" /psig="0.997002997002997" /xcortree=1998 /SigmaFactorBS="gaaacatgagtaaagatacgggcagcgccagctgtctttttt tATgtgtttttttcggttTTTGATACACTAGAGAAAGAacgacaaaattggaggcttt g" /listShort="ydcI, S167, ydcK" /listLong="S168, trnS-Asn, trnS-Ser, trnS-Glu, trnS-Gln, trnS-Lys, trnS-Leu1, trnS-Leu2" CDS 525743..527902 /gene="tex" /locus_tag="BSU_04780" /old_locus_tag="BSU04780" /function="16.3: Control" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 8755871, 12910271, 15383836, 16282592; Product type f: factor" /codon_start=1 /transl_table=11 /product="RNA helicase transcriptional accessory protein" /protein_id="NP_388359.2" /db_xref="EnsemblGenomes-Gn:BSU04780" /db_xref="EnsemblGenomes-Tr:CAB12285" /db_xref="GOA:O31489" /db_xref="InterPro:IPR003029" /db_xref="InterPro:IPR006641" /db_xref="InterPro:IPR010994" /db_xref="InterPro:IPR012337" /db_xref="InterPro:IPR012340" /db_xref="InterPro:IPR018974" /db_xref="InterPro:IPR022967" /db_xref="InterPro:IPR023319" /db_xref="InterPro:IPR023323" /db_xref="InterPro:IPR032639" /db_xref="SubtiList:BG12096" /db_xref="UniProtKB/Swiss-Prot:O31489" /translation="METSALLKQQIAKEIGLSQKHVESVIRLLEDGNTVPFIARYRKE QTGSMDEVQIQTISERWQYIQNLNQRKEEVIRLIAEQDKLTDNLKRKIEQSVKLQEVE DLYRPYKQKRKTKATVAKSKGLEPLADYILTLPQDDHLAATADQYISEEKEVFTREEA IEGAKHIIAEQISDEPTFRKWIRQETFKRGTIKSAAGKSADTDEKNVYEMYYEYEEPI AKVVPHRVLAMNRGEKEDILKVAIEPPADHIKAYLEKQIIKNRSTSVREILQETIEDS YKRLIQPAIEREIRKELSEKADEQAIHIFSENLRKLLLQPPMKGKTVLGVDPAFRTGC KLAVSDETGKVLKIDVIYPHAPVNKTKEAHEKVKKILEQYQVEMVAIGNGTASRETEQ FIVNVLRDMPRKIYYVIVNEAGASVYSASELAREEFPDLKVEERSAVSIARRLQDPLA ELVKIDPKSVGVGQYQHDVSQKRLNESLRFVVETVVNQVGVNVNTASAALLQYVAGLS KSVAGNVVKKREEIGKFSNRKELKDIPRLGAKTYEQCIGFLRVQEGTEPLDRTGIHPE SYKETKALLKKLGLSTEHIGTAELKDKINQLALSETAKELGIGEITLKDICEQLTRPE RDPRDKVPKPLLKTDVLQLEDLKEGMELQGTVRNVVDFGAFVDIGVKQDGLVHISKLS NQFVKHPLDVVSVGDIVTVWVDGVDVQKGRVSLSMVK*" gene 525743..527902 /gene="tex" /locus_tag="BSU_04780" /old_locus_tag="BSU04780" misc_feature 527890..527909 /Source="Nicolas_upshift_promotors" /id="U378" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.995004995004995" /psig="0.999000999001" /xcortree=2162 /SigmaFactorBS="gacggcgtagatgtacaaaaaggcagagtatcgctgtcTATG GTAAAATAAAAGCACTgcttacgagcagtgttttttcctatagaaataccagcattga t" /listShort="S167, ydcK, S168, trnS-Asn, trnS-Ser, trnS-Glu, trnS-Gln, trnS-Lys, trnS-Leu1" /listLong="trnS-Leu2, S169" /label="promotor_single_box" /note="Geneious type: promotor_single_box" S_feature 527912..528128 /Source="Nicolas_S_feature" /locus_tag="new_527912_528128" /HighExp="Cold, Etha, LBGstat, dia5, LPhT, T4.0H, dia15, T3.0H, T2.30H, T3.30H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="0.999, 0.997" /TUlongSig="NA" /TUlongPSig="NA" /label="S167" upshifts 527912 /Source="Nicolas_upshifts" /id="U378" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.995004995004995" /psig="0.999000999001" /xcortree=2162 /SigmaFactorBS="gacggcgtagatgtacaaaaaggcagagtatcgctgtcTATG GTAAAATAAAAGCACTgcttacgagcagtgttttttcctatagaaataccagcattga t" /listShort="S167, ydcK, S168, trnS-Asn, trnS-Ser, trnS-Glu, trnS-Gln, trnS-Lys, trnS-Leu1" /listLong="trnS-Leu2, S169" CDS complement(527912..528025) /gene="cmpA" /locus_tag="BSU_04785" /old_locus_tag="BSU04785" /function="16.3: Control" /function="16.6: Maintain" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:22463703, 26387458" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 22463703, 26387458; Product type f: factor" /codon_start=1 /transl_table=11 /product="factor allowing degradation of SpoIVA by ClpXP" /protein_id="YP_009513946.1" /translation="MPNWLKKQMQKAFLEKDNYQIKLLNQCWYFYRKKHCS*" gene complement(527912..528025) /gene="cmpA" /locus_tag="BSU_04785" /old_locus_tag="BSU04785" promotor_-10 complement(528065..528084) /Source="Nicolas_upshift_promotors" /id="U379" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.994005994005994" /psig="0.994005994005994" /xcortree=1320 /SigmaFactorBS="tctttgttatccatggtgcacctcacttaaaaaacATTGAAC GGgacaattcaccgttCGCATACAATATGGTAATCActgtccctcttatgataaaagc t" /listShort="S166" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(528082) /Source="Nicolas_upshifts" /id="U379" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.994005994005994" /psig="0.994005994005994" /xcortree=1320 /SigmaFactorBS="tctttgttatccatggtgcacctcacttaaaaaacATTGAAC GGgacaattcaccgttCGCATACAATATGGTAATCActgtccctcttatgataaaagc t" /listShort="S166" /GFF_Attribute="listLong" promotor_-35 complement(528099..528107) /Source="Nicolas_upshift_promotors" /id="U379" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.994005994005994" /psig="0.994005994005994" /xcortree=1320 /SigmaFactorBS="tctttgttatccatggtgcacctcacttaaaaaacATTGAAC GGgacaattcaccgttCGCATACAATATGGTAATCActgtccctcttatgataaaagc t" /listShort="S166" /GFF_Attribute="listLong" /label="promotor_-35" CDS 528129..528581 /gene="ydcK" /locus_tag="BSU_04790" /old_locus_tag="BSU04790" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_388360.1" /db_xref="EnsemblGenomes-Gn:BSU04790" /db_xref="EnsemblGenomes-Tr:CAB12286" /db_xref="GOA:P96628" /db_xref="InterPro:IPR006640" /db_xref="InterPro:IPR023524" /db_xref="InterPro:IPR035240" /db_xref="SubtiList:BG12098" /db_xref="UniProtKB/Swiss-Prot:P96628" /translation="MDNKELQKLTEDISETYFKKPFRHQALFNDRLKTTGGRYLLTSH NIELNRKYLIEHGREELIGIIKHELCHYHLHLEGKGYKHRDRDFRMLLQQVNAPRFCT PLKKKAENKKTYMYICTTCGQQYIKKRAMNPDRYRCGKCRGKIKRIFS*" gene 528129..528581 /gene="ydcK" /locus_tag="BSU_04790" /old_locus_tag="BSU04790" promotor_-35 528587..528593 /Source="Nicolas_upshift_promotors" /id="U380" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.576423576423576" /psig=1 /xcortree=2626 /SigmaFactorBS="gaaaaataaaaagaattttttcgtgaaaaagGTTGACGaata tggcaagcctATGTTACATTATAAAAGTCGtcacgagagataaataaaaacatttacc t" /listShort="S168, trnS-Asn, trnS-Ser, trnS-Glu, trnS-Gln, trnS-Lys, trnS-Leu1, trnS-Leu2, S169" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 528608..528627 /Source="Nicolas_upshift_promotors" /id="U380" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.576423576423576" /psig=1 /xcortree=2626 /SigmaFactorBS="gaaaaataaaaagaattttttcgtgaaaaagGTTGACGaata tggcaagcctATGTTACATTATAAAAGTCGtcacgagagataaataaaaacatttacc t" /listShort="S168, trnS-Asn, trnS-Ser, trnS-Glu, trnS-Gln, trnS-Lys, trnS-Leu1, trnS-Leu2, S169" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 528616..528703 /Source="Nicolas_S_feature" /locus_tag="new_528616_528703" /HighExp="C30, LBGstat, Cold, UNK1, GM 25, GM 120, GM 15, Heat, T-3.40H, GM 90" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="1, 0.999" /TUlongSig="SigA" /TUlongPSig="0.997" /label="S168" upshifts 528616 /Source="Nicolas_upshifts" /id="U380" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.576423576423576" /psig=1 /xcortree=2626 /SigmaFactorBS="gaaaaataaaaagaattttttcgtgaaaaagGTTGACGaata tggcaagcctATGTTACATTATAAAAGTCGtcacgagagataaataaaaacatttacc t" /listShort="S168, trnS-Asn, trnS-Ser, trnS-Glu, trnS-Gln, trnS-Lys, trnS-Leu1, trnS-Leu2, S169" /GFF_Attribute="listLong" downshifts complement(528648) /Source="Nicolas_upshifts" /id="D227" /incds=0 /nref=1 /ntot=28 /MaxReadThrough="2.50342" /MaxDrop="3.97305" /score="8.78044068" /energy="-9.2" /TU="NA" /idTUdmin="U381" /TUdmin=704 /isTUend="FALSE" tRNA 528704..528778 /gene="trnS-Asn" /locus_tag="BSU_tRNA_45" /product="tRNA-Asn" /inference="profile:tRNAscan:1.23" /note="transfer RNA-Asn(GUU); Evidence 2a: Function from experimental evidences in other organisms; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene 528704..528778 /gene="trnS-Asn" /locus_tag="BSU_tRNA_45" tRNA 528783..528873 /gene="trnS-Ser" /locus_tag="BSU_tRNA_46" /product="tRNA-Ser" /inference="profile:tRNAscan:1.23" /note="transfer RNA-Ser(GCU); Evidence 2a: Function from experimental evidences in other organisms; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene 528783..528873 /gene="trnS-Ser" /locus_tag="BSU_tRNA_46" tRNA 528903..528974 /gene="trnS-Glu" /locus_tag="BSU_tRNA_47" /product="tRNA-Glu" /inference="profile:tRNAscan:1.23" /note="Evidence 2a: Function from experimental evidences in other organisms; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene 528903..528974 /gene="trnS-Glu" /locus_tag="BSU_tRNA_47" tRNA 528986..529060 /gene="trnS-Gln" /locus_tag="BSU_tRNA_48" /product="tRNA-Gln" /inference="profile:tRNAscan:1.23" /note="transfer RNA-Gln(UUG); Evidence 2a: Function from experimental evidences in other organisms; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene 528986..529060 /gene="trnS-Gln" /locus_tag="BSU_tRNA_48" tRNA 529087..529162 /gene="trnS-Lys" /locus_tag="BSU_tRNA_49" /product="tRNA-Lys" /inference="profile:tRNAscan:1.23" /note="transfer RNA-Lys(UUU); Evidence 2a: Function from experimental evidences in other organisms; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene 529087..529162 /gene="trnS-Lys" /locus_tag="BSU_tRNA_49" tRNA 529174..529255 /gene="trnS-Leu1" /locus_tag="BSU_tRNA_50" /product="tRNA-Leu" /inference="profile:tRNAscan:1.23" /note="transfer RNA-Leu(UAG); Evidence 2a: Function from experimental evidences in other organisms; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene 529174..529255 /gene="trnS-Leu1" /locus_tag="BSU_tRNA_50" downshifts 529320 /Source="Nicolas_upshifts" /id="D228" /incds=0 /nref=3 /ntot=136 /MaxReadThrough="6.94232" /MaxDrop="3.5424" /score="34.987622" /energy="-13.7" /TU="U380" /idTUdmin="U378" /TUdmin=0 /isTUend="TRUE" tRNA 529336..529422 /gene="trnS-Leu2" /locus_tag="BSU_tRNA_51" /product="tRNA-Leu" /inference="profile:tRNAscan:1.23" /note="transfer RNA-Leu (GAG); Evidence 2a: Function from experimental evidences in other organisms; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene 529336..529422 /gene="trnS-Leu2" /locus_tag="BSU_tRNA_51" downshifts 529409 /Source="Nicolas_upshifts" /id="D229" /incds=0 /nref=82 /ntot=235 /MaxReadThrough="4.38481" /MaxDrop="5.23398" /score="34.987622" /energy="-13.7" /TU="U380" /idTUdmin="U378" /TUdmin=89 /isTUend="FALSE" S_feature 529454..530352 /Source="Nicolas_S_feature" /locus_tag="new_529454_530352" /HighExp="Cold, G180, G135, Paraq, Oxctl, C30, G150, H2O2, Fru, Lbexp" /AntisenseName="ydcL" /AntisenseCor="-0.23338643759911901" /AntisenseRegPval="-4" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="SigA" /TUlongPSig="0.999" /label="S169" downshifts complement(529477) /Source="Nicolas_upshifts" /id="D230" /incds=0 /nref=96 /ntot=231 /MaxReadThrough="2.93365" /MaxDrop="6.05127" /score="8.78044068" /energy="-9.2" /TU="U381" /idTUdmin="U381" /TUdmin="-125" /isTUend="FALSE" CDS complement(529505..530611) /gene="ydcL" /locus_tag="BSU_04800" /old_locus_tag="BSU04800" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 22505685; Product type h : extrachromosomal origin" /codon_start=1 /transl_table=11 /product="ICEBs1 mobile element: integrase" /protein_id="NP_388361.1" /db_xref="EnsemblGenomes-Gn:BSU04800" /db_xref="EnsemblGenomes-Tr:CAB12287" /db_xref="GOA:P96629" /db_xref="InterPro:IPR002104" /db_xref="InterPro:IPR004107" /db_xref="InterPro:IPR010998" /db_xref="InterPro:IPR011010" /db_xref="InterPro:IPR013762" /db_xref="SubtiList:BG12099" /db_xref="UniProtKB/Swiss-Prot:P96629" /translation="MSVKKLENGQYQVDVSFGFDPITGERIRTRPVASTRKEALELEA KLRREFQEERARKSRSVSFPTLISIYLASCEIDSKPNYYQNQKYIINKHISDYFLKSD IQKITHREITDFRKHLMETGLSNKSVNNIMTSLSKIFDTAVHEEILKRNPCDNVKRLP LTRKKMKFWRPEEFKKFISLIPQDQLLFKTFYTVAFLTGLRCGEMLALQWKDIDKILL EIDVHKSCTWLDGQFVVTTPKTKNSIRRVSINKKLLKLLERWKEAQEELFNELGIRHS HDTYIFQYKDTPSRKDIFSRKIKYFCKDSDLTPIRLHDFRHSHVALLIHQGEDYITIK ERLGHGSVKTTIDVYGHLYPNKQKEMADKLDDLL*" gene complement(529505..530611) /gene="ydcL" /locus_tag="BSU_04800" /old_locus_tag="BSU04800" CDS complement(530624..531133) /gene="immA" /locus_tag="BSU_04810" /old_locus_tag="BSU04810" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:18761623, 21036995, 22505685" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 18761623, 21036995, 22505685; Product type h: extrachromosomal origin" /codon_start=1 /transl_table=11 /product="ICEBs1 mobile element: site-specific protease cleaving ImmR" /protein_id="NP_388362.1" /db_xref="EnsemblGenomes-Gn:BSU04810" /db_xref="EnsemblGenomes-Tr:CAB12288" /db_xref="GOA:P96630" /db_xref="InterPro:IPR010359" /db_xref="SubtiList:BG12100" /db_xref="UniProtKB/Swiss-Prot:P96630" /translation="MITIYTSKGIKHKVQSVIKTHGTNNVYEICDIQKIYILKNDLGQ ANGLLQHDKATDQYLIHINENLQHQQFVIAHELGHYFLHKRLNTFKVVNCSKVLKDKL EHQASLFASELILTDKMLNEALPYIQGFSKEQIAAYFNVPSFVTDYKLSQIGSFSNRI YSHEISAFG*" gene complement(530624..531133) /gene="immA" /locus_tag="BSU_04810" /old_locus_tag="BSU04810" downshifts complement(530936) /Source="Nicolas_upshifts" /id="D231" /incds=1 /nref=12 /ntot=39 /MaxReadThrough="6.14325" /MaxDrop="3.22989" /score="17.0287275" /energy="-11.8" /TU="U381" /idTUdmin="U384" /TUdmin=1518 /isTUend="FALSE" CDS complement(531130..531513) /gene="immR" /locus_tag="BSU_04820" /old_locus_tag="BSU04820" /function="16.5: Explore" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:8083175, 17511812, 22505685" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8083175, 17511812, 22505685; Product type h: extrachromosomal origin" /codon_start=1 /transl_table=11 /product="ICEBs1 mobile element: transcriptional regulator(Xre family)" /protein_id="NP_388363.1" /db_xref="EnsemblGenomes-Gn:BSU04820" /db_xref="EnsemblGenomes-Tr:CAB12289" /db_xref="GOA:P96631" /db_xref="InterPro:IPR001387" /db_xref="InterPro:IPR010982" /db_xref="InterPro:IPR027910" /db_xref="SubtiList:BG12101" /db_xref="UniProtKB/Swiss-Prot:P96631" /translation="MSLGKRLKEARQKAGYTQKEAAEKLNIGNNNLSNYERDYRDPDT DTLLKLSNLYNVSTDYLLGKDEVSKKNETDLLNKTINEAIQELKDEDTLLFMNDGEFD EETARLVKKALKNGIKFIDELKKKE*" gene complement(531130..531513) /gene="immR" /locus_tag="BSU_04820" /old_locus_tag="BSU04820" promotor_-10 complement(531542..531561) /Source="Nicolas_upshift_promotors" /id="U381" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.967032967032967" /psig=1 /xcortree=3028 /SigmaFactorBS="tagaattatttatttaacttataggtgaaatTAATGAATtct ccaaaaaatgtTGTTATTATTTTTATAAAAAtcaactctttgtgaaatggatgataaa a" /listShort="immR, immA, ydcL" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(531554) /Source="Nicolas_upshifts" /id="U381" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.967032967032967" /psig=1 /xcortree=3028 /SigmaFactorBS="tagaattatttatttaacttataggtgaaatTAATGAATtct ccaaaaaatgtTGTTATTATTTTTATAAAAAtcaactctttgtgaaatggatgataaa a" /listShort="immR, immA, ydcL" /GFF_Attribute="listLong" promotor_-35 complement(531576..531583) /Source="Nicolas_upshift_promotors" /id="U381" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.967032967032967" /psig=1 /xcortree=3028 /SigmaFactorBS="tagaattatttatttaacttataggtgaaatTAATGAATtct ccaaaaaatgtTGTTATTATTTTTATAAAAAtcaactctttgtgaaatggatgataaa a" /listShort="immR, immA, ydcL" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 531713..531720 /Source="Nicolas_upshift_promotors" /id="U382" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.98001998001998" /psig=1 /xcortree=2860 /SigmaFactorBS="tgttcaaaaaaatacactttaaggtgaattttgTGTTGACTt acacgaaaaggagTTTTATAATAAAGTTAATTCacaaagagttgagttaacgaggagg t" /listShort="sacV, ydzL, ydcO, S171, ydcP, ydcQ, ydcR" /listLong="S172, ydcS, ydcT, yddA, yddB, yddC, yddD, yddE, yddF, yddG, yddH, yddI, yddJ" /label="promotor_-35" promotor_-10 531735..531754 /Source="Nicolas_upshift_promotors" /id="U382" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.98001998001998" /psig=1 /xcortree=2860 /SigmaFactorBS="tgttcaaaaaaatacactttaaggtgaattttgTGTTGACTt acacgaaaaggagTTTTATAATAAAGTTAATTCacaaagagttgagttaacgaggagg t" /listShort="sacV, ydzL, ydcO, S171, ydcP, ydcQ, ydcR" /listLong="S172, ydcS, ydcT, yddA, yddB, yddC, yddD, yddE, yddF, yddG, yddH, yddI, yddJ" /label="promotor_-10" upshifts 531740 /Source="Nicolas_upshifts" /id="U382" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.98001998001998" /psig=1 /xcortree=2860 /SigmaFactorBS="tgttcaaaaaaatacactttaaggtgaattttgTGTTGACTt acacgaaaaggagTTTTATAATAAAGTTAATTCacaaagagttgagttaacgaggagg t" /listShort="sacV, ydzL, ydcO, S171, ydcP, ydcQ, ydcR" /listLong="S172, ydcS, ydcT, yddA, yddB, yddC, yddD, yddE, yddF, yddG, yddH, yddI, yddJ" CDS 531787..531981 /gene="xis" /locus_tag="BSU_04830" /old_locus_tag="BSU04830" /function="16.3: Control" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:3269394, 17511812, 22505685, 26013486" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 3269394, 17511812, 22505685, 26013486; Product type h: extrachromosomal origin" /codon_start=1 /transl_table=11 /product="ICEBs1 mobile element: excisionase" /protein_id="NP_388364.1" /db_xref="EnsemblGenomes-Gn:BSU04830" /db_xref="EnsemblGenomes-Tr:CAB12290" /db_xref="GOA:O31490" /db_xref="SubtiList:BG12670" /db_xref="UniProtKB/Swiss-Prot:O31490" /translation="MKGEFLTARDIQKILGVKQAKSYDIIRTLNAQMKEEGYMVIQGK VSRAKFEECYCYKGPKSQTG*" gene 531787..531981 /gene="xis" /locus_tag="BSU_04830" /old_locus_tag="BSU04830" CDS 531978..532238 /gene="ydzL" /locus_tag="BSU_04839" /old_locus_tag="BSU04839" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 22505685, 26013486; Product type h:extrachromosomal origin" /codon_start=1 /transl_table=11 /product="ICEBs1 mobile element: conserved protein of unknown function" /protein_id="YP_003097681.1" /db_xref="EnsemblGenomes-Gn:BSU04839" /db_xref="EnsemblGenomes-Tr:CAX52552" /db_xref="UniProtKB/Swiss-Prot:C0H3V5" /translation="MIFINIDITNSFMKEAVPLARQMEGDWIARMKIALNSVIINHYL NLPLTIENVNELLRKGVSYRRICKHYGIGRKDIEKLRQSSVV*" gene 531978..532238 /gene="ydzL" /locus_tag="BSU_04839" /old_locus_tag="BSU04839" CDS 532292..532552 /gene="ydcO" /locus_tag="BSU_04840" /old_locus_tag="BSU04840" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 22505685, 26013486; Product type h:extrachromosomal origin" /codon_start=1 /transl_table=11 /product="ICEBs1 mobile element: conserved protein of unknown function" /protein_id="NP_388365.1" /db_xref="EnsemblGenomes-Gn:BSU04840" /db_xref="EnsemblGenomes-Tr:CAB12291" /db_xref="SubtiList:BG12102" /db_xref="UniProtKB/Swiss-Prot:P96632" /translation="MKIRVNATIITDVEALKADKDLNHFKDYATCETFVVDADNHLKA NEEISELLKGWDWWCIWSTRPLSKKDNQVFTLYNDDLYNLCR*" gene 532292..532552 /gene="ydcO" /locus_tag="BSU_04840" /old_locus_tag="BSU04840" S_feature complement(532412..532652) /Source="Nicolas_S_feature" /locus_tag="new_532412_532652_c" /HighExp="T5.0H, T4.0H, T3.0H, Lbstat, T3.30H, T2.0H, Cold, Gly, S2, T2.30H" /AntisenseName="ydcO" /AntisenseCor="0.131178357364787" /AntisenseRegPval="-1.5" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.987" /TUlongSig="NA" /TUlongPSig="NA" /label="S170" promotor_-35 532578..532585 /Source="Nicolas_upshift_promotors" /id="U383" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.984015984015984" /psig="0.99000999000999" /xcortree=2861 /SigmaFactorBS="tgtcgataggagtgtttgttccttgaaaactacaTATAGACA aaaaaagcgccttgACGAATGATCATCAAGAACGccggaaaataaaaactagacactt t" /listShort="S171, ydcP, ydcQ, ydcR, S172, ydcS, ydcT, yddA, yddB, yddC, yddD, yddE, yddF, yddG, yddH, yddI, yddJ" /GFF_Attribute="listLong" /label="promotor_-35" misc_RNA complement(532583..532642) /gene="sncO" /locus_tag="BSU_misc_RNA_65" /product="ICEBs1 mobile element: conserved small untranslated RNA" /experiment="publication(s) with functional evidences, PMID:20525796, 22505685" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 20525796, 22505685; Product type n: RNA" gene complement(532583..532642) /gene="sncO" /locus_tag="BSU_misc_RNA_65" promotor_-10 532600..532619 /Source="Nicolas_upshift_promotors" /id="U383" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.984015984015984" /psig="0.99000999000999" /xcortree=2861 /SigmaFactorBS="tgtcgataggagtgtttgttccttgaaaactacaTATAGACA aaaaaagcgccttgACGAATGATCATCAAGAACGccggaaaataaaaactagacactt t" /listShort="S171, ydcP, ydcQ, ydcR, S172, ydcS, ydcT, yddA, yddB, yddC, yddD, yddE, yddF, yddG, yddH, yddI, yddJ" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 532604..532921 /Source="Nicolas_S_feature" /locus_tag="new_532604_532921" /HighExp="T0.30H, T0.0H, T1.0H, T1.30H, T-0.40H, T2.0H, HiOs, T2.30H, MG 120, T-1.10H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="0.99, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S171" upshifts 532604 /Source="Nicolas_upshifts" /id="U383" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.984015984015984" /psig="0.99000999000999" /xcortree=2861 /SigmaFactorBS="tgtcgataggagtgtttgttccttgaaaactacaTATAGACA aaaaaagcgccttgACGAATGATCATCAAGAACGccggaaaataaaaactagacactt t" /listShort="S171, ydcP, ydcQ, ydcR, S172, ydcS, ydcT, yddA, yddB, yddC, yddD, yddE, yddF, yddG, yddH, yddI, yddJ" /GFF_Attribute="listLong" promotor_-10 complement(532637..532656) /Source="Nicolas_upshift_promotors" /id="U384" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.78021978021978" /psig="0.987012987012987" /xcortree=3113 /SigmaFactorBS="tttaaagtgattgctgttcatcactcaaatactcaCGCATGA CatttcaacaagaaTACCGTATAATAAAAGTGTCtagtttttattttccggcgttctt g" /listShort="S170" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(532652) /Source="Nicolas_upshifts" /id="U384" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.78021978021978" /psig="0.987012987012987" /xcortree=3113 /SigmaFactorBS="tttaaagtgattgctgttcatcactcaaatactcaCGCATGA CatttcaacaagaaTACCGTATAATAAAAGTGTCtagtttttattttccggcgttctt g" /listShort="S170" /GFF_Attribute="listLong" promotor_-35 complement(532670..532677) /Source="Nicolas_upshift_promotors" /id="U384" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.78021978021978" /psig="0.987012987012987" /xcortree=3113 /SigmaFactorBS="tttaaagtgattgctgttcatcactcaaatactcaCGCATGA CatttcaacaagaaTACCGTATAATAAAAGTGTCtagtttttattttccggcgttctt g" /listShort="S170" /GFF_Attribute="listLong" /label="promotor_-35" CDS 532758..532886 /locus_tag="BSU_04849" /old_locus_tag="BSU04849" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function; PubMedId : 22505685" /codon_start=1 /transl_table=11 /product="ICEBs1 mobile element: hypothetical protein" /protein_id="YP_009513947.1" /translation="MMAIISLLGCHEGVKPLATDKRQDGYRTGANQKHKIEINVLL*" gene 532758..532886 /locus_tag="BSU_04849" /old_locus_tag="BSU04849" CDS 532922..533302 /gene="helP" /locus_tag="BSU_04850" /old_locus_tag="BSU04850" /experiment="publication(s) with functional evidences, PMID:22505685, 23326247, 26013486" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 22505685, 23326247, 26013486; Product type h: extrachromosomal origin" /codon_start=1 /transl_table=11 /product="ICEBs1 mobile element: helicase processivity factor" /protein_id="NP_388366.1" /db_xref="EnsemblGenomes-Gn:BSU04850" /db_xref="EnsemblGenomes-Tr:CAB12292" /db_xref="InterPro:IPR010365" /db_xref="SubtiList:BG12103" /db_xref="UniProtKB/Swiss-Prot:P96633" /translation="MNLNFIVPDINMTFGDMKFMGLNRERYVYDRENNKRTDVLESRI YNIASAVQGGQIEVTIPEYAGAKEIPPFADIELKNPKISAMATSQRDSTYANVMWKLE ADDIVVKGGSSVKPAAATGGNEKK*" gene 532922..533302 /gene="helP" /locus_tag="BSU_04850" /old_locus_tag="BSU04850" CDS 533338..534780 /gene="conQ" /locus_tag="BSU_04860" /old_locus_tag="BSU04860" /experiment="publication(s) with functional evidences, PMID:17511812, 22505685, 26013486" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 17511812, 22505685, 26013486; Product type h: extrachromosomal origin" /codon_start=1 /transl_table=11 /product="ICEBs1 mobile element: coupling conjugation protein VirD4" /protein_id="NP_388367.1" /db_xref="EnsemblGenomes-Gn:BSU04860" /db_xref="EnsemblGenomes-Tr:CAB12293" /db_xref="GOA:P96634" /db_xref="InterPro:IPR002543" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG12104" /db_xref="UniProtKB/Swiss-Prot:P96634" /translation="MSDFLNKRFWKYRGKRIRPYMRNNVKLAGAIIFVPVFLLSMFLF WREQLIHFDLSQVIKNFEWNVPLIIKSVLCSVLIAVGSIVASYFLLFDSYKKILHRQK IAKMIFSNKFYEKENVKVRKIFSNETDSKEKITYFPRMYYQVKNNHIYIRIAMDMSRF QNRFLDLGKDLENGLFCDLVDKQMEEGFVCFKLLYDVKKNRISIDDAVAENGVLPLMK HISWQFDKLPHMLIAGGTGGGKTYFMLTIIKACVGLGADVRILDPKNADLADLEEVLP KKVYSQKNGILMCLRKSVDGMMERMDEMKQMSNYKTGENYAYLGLKPVFIFFDEYVAF MDLLDMKERNEALSYMKQLVMLGRQAGYFLVLGAQRPDAKYLADGIRDQFSFRVSLGL MSDTGYGMMFGDVEKAYVNKKETGRGYANVGTGSVLEFYSPIVPKGYDFMSSIKNALV GVEGAQATAVASGSVSDQTASGEGVSEANG*" gene 533338..534780 /gene="conQ" /locus_tag="BSU_04860" /old_locus_tag="BSU04860" CDS 534773..535831 /gene="nicK" /locus_tag="BSU_04870" /old_locus_tag="BSU04870" /experiment="publication(s) with functional evidences, PMID:17511812, 17693500, 22505685, 26013486" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 17511812, 17693500, 22505685, 26013486; Product type h: extrachromosomal origin" /codon_start=1 /transl_table=11 /product="ICEBs1 mobile element: DNA relaxase" /protein_id="NP_388368.1" /db_xref="EnsemblGenomes-Gn:BSU04870" /db_xref="EnsemblGenomes-Tr:CAB12294" /db_xref="GOA:P96635" /db_xref="InterPro:IPR003491" /db_xref="SubtiList:BG12105" /db_xref="UniProtKB/Swiss-Prot:P96635" /translation="MDELKQPPHANRGVVIVKEKNEAVESPLVSMVDYIRVSFKTHDV DRIIEEVLHLSKDFMTEKQSGFYGYVGTYELDYIKVFYSAPDDNRGVLIEMSGQGCRQ FESFLECRKKTWYDFFQDCMQQGGSFTRFDLAIDDKKTYFSIPELLKKAQKGECISRF RKSDFNGSFDLSDGITGGTTIYFGSKKSEAYLCFYEKNYEQAEKYNIPLEELGDWNRY ELRLKNERAQVAIDALLKTKDLTLIAMQIINNYVRFVDADENITREHWKTSLFWSDFI GDVGRLPLYVKPQKDFYQKSRNWLRNSCAPTMKMVLEADEHLGKTDLSDMIAEAELAD KHKKMLDVYMADVADMVV*" gene 534773..535831 /gene="nicK" /locus_tag="BSU_04870" /old_locus_tag="BSU04870" downshifts 534776 /Source="Nicolas_upshifts" /id="D232" /incds=0 /nref=1 /ntot=1 /MaxReadThrough="5.48512" /MaxDrop="3.25403" /score="-9.5933493" /energy="-23.1" /TU="U382,U383" /idTUdmin="U382" /TUdmin="-176" /isTUend="FALSE" S_feature 535832..536095 /Source="Nicolas_S_feature" /locus_tag="new_535832_536095" /HighExp="T0.30H, T1.0H, T1.30H, T0.0H, T2.0H, T2.30H, T-0.40H, T3.0H, T3.30H, MG 120" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.99" /TUlongSig="SigA" /TUlongPSig=1 /label="S172" CDS 536096..536365 /gene="ydcS" /locus_tag="BSU_04880" /old_locus_tag="BSU04880" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 22505685; Product type h :extrachromosomal origin" /codon_start=1 /transl_table=11 /product="ICEBs1 mobile element: conserved protein of unknown function" /protein_id="NP_388369.1" /db_xref="EnsemblGenomes-Gn:BSU04880" /db_xref="EnsemblGenomes-Tr:CAB12295" /db_xref="SubtiList:BG12106" /db_xref="UniProtKB/Swiss-Prot:P96636" /translation="MHNVNLLNQAGLENALESVGCLDIVEDLIEKMQEYVLYHTETAE RFAIDIFTVVNNYTKKVHAIFNVLENEDGETNVKNVEFEVMHFTE*" gene 536096..536365 /gene="ydcS" /locus_tag="BSU_04880" /old_locus_tag="BSU04880" promotor_-10 complement(536156..536175) /Source="Nicolas_upshift_promotors" /id="U385" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.956043956043956" /psig="0.998001998001998" /xcortree=2065 /SigmaFactorBS="aatctttcggcagtttcggtatgatacaaaacataTTCCTGC AtcttttctattaaaTCTTCTACAATATCTAAACAgccaactgattccaaagcatttt c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(536172) /Source="Nicolas_upshifts" /id="U385" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.956043956043956" /psig="0.998001998001998" /xcortree=2065 /SigmaFactorBS="aatctttcggcagtttcggtatgatacaaaacataTTCCTGC AtcttttctattaaaTCTTCTACAATATCTAAACAgccaactgattccaaagcatttt c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(536190..536197) /Source="Nicolas_upshift_promotors" /id="U385" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.956043956043956" /psig="0.998001998001998" /xcortree=2065 /SigmaFactorBS="aatctttcggcagtttcggtatgatacaaaacataTTCCTGC AtcttttctattaaaTCTTCTACAATATCTAAACAgccaactgattccaaagcatttt c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" CDS 536404..536670 /gene="ydcT" /locus_tag="BSU_04890" /old_locus_tag="BSU04890" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 22505685; Product type h :extrachromosomal origin" /codon_start=1 /transl_table=11 /product="ICEBs1 mobile element: conserved protein of unknown function" /protein_id="NP_388370.1" /db_xref="EnsemblGenomes-Gn:BSU04890" /db_xref="EnsemblGenomes-Tr:CAB12296" /db_xref="SubtiList:BG12107" /db_xref="UniProtKB/Swiss-Prot:P96637" /translation="MFNINLLNQARLESDLDSLGCLDIAEELIEKMMEDVFYSDVAQR IIVQTLAVINNANAKLQATFNILEDEDMETDERSVEFEGISYYE*" gene 536404..536670 /gene="ydcT" /locus_tag="BSU_04890" /old_locus_tag="BSU04890" CDS 536687..536995 /gene="yddA" /locus_tag="BSU_04900" /old_locus_tag="BSU04900" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 22505685; Product type h :extrachromosomal origin" /codon_start=1 /transl_table=11 /product="ICEBs1 mobile element: conserved protein of unknown function" /protein_id="NP_388371.1" /db_xref="EnsemblGenomes-Gn:BSU04900" /db_xref="EnsemblGenomes-Tr:CAB12297" /db_xref="SubtiList:BG12108" /db_xref="UniProtKB/Swiss-Prot:P96638" /translation="MSAVDKRFKSLGFNVGIPSLVFVRSLSRDCMLVVEGERVKGFAE YRYTFYKTRYLPDGRMTSLKVYMENQSIKRVLHRVASFLSFLERTKQIEQKECEKVAQ *" gene 536687..536995 /gene="yddA" /locus_tag="BSU_04900" /old_locus_tag="BSU04900" CDS 536985..538049 /gene="conB" /locus_tag="BSU_04910" /old_locus_tag="BSU04910" /experiment="publication(s) with functional evidences, PMID:22505685, 26013486" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 22505685, 26013486; Product type h: extrachromosomal origin" /codon_start=1 /transl_table=11 /product="ICEBs1 mobile element: subunit of the conjugation machinery VirB8" /protein_id="NP_388372.1" /db_xref="EnsemblGenomes-Gn:BSU04910" /db_xref="EnsemblGenomes-Tr:CAB12298" /db_xref="GOA:O31491" /db_xref="InterPro:IPR024735" /db_xref="InterPro:IPR035628" /db_xref="SubtiList:BG12109" /db_xref="UniProtKB/Swiss-Prot:O31491" /translation="MLNKEIGSDKKEESFFRSAFQKLKRIERPEKDKQKVPRDRSKLI AVTLWSCVGSLLFICLLAVLLSINTRSQLNDMKDETNKPTNDDKQKISVTAAENFLSG FINEYMNVKNDQESIEKRMQSLESYMVKQEDNHFEDEERFNVDGLKGDRELKGYSLYN VKEGDKNSLFQYKVTYENLYPVEKEVEKEVKDGKKKKKVKEKVKTNEKYEKQMLLNIP VTNKGDSFAVSAVPYFTQIYDLKGDIAFKGKEETRDEYAGEKKESIESFLQNFFEKYA SEKKEEMVYMMKKPEALEGNLLFGEVQSVKIFETKKGFEVFCAVRFKEKENDIPVNEK FSLEITENSGQFYVNKLKHQ*" gene 536985..538049 /gene="conB" /locus_tag="BSU_04910" /old_locus_tag="BSU04910" misc_feature 537523..537530 /Source="Nicolas_upshift_promotors" /id="U386" /multdbtbs="-" /comp="M21" /sig="Sig-" /pcomp="0.363636363636364" /psig="0.454545454545455" /xcortree=1489 /SigmaFactorBS="tgaaagaaggtgataaaaacagcctttttcaatataaggtca catatgaaaatctatACCCTGTAgaaaaggaagttgaaaaagaagttaaagacggaaa g" /listShort="yddC, yddD, yddE, yddF, yddG, yddH, yddI" /listLong="yddJ" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 537526 /Source="Nicolas_upshifts" /id="U386" /multdbtbs="-" /comp="M21" /sig="Sig-" /pcomp="0.363636363636364" /psig="0.454545454545455" /xcortree=1489 /SigmaFactorBS="tgaaagaaggtgataaaaacagcctttttcaatataaggtca catatgaaaatctatACCCTGTAgaaaaggaagttgaaaaagaagttaaagacggaaa g" /listShort="yddC, yddD, yddE, yddF, yddG, yddH, yddI" /listLong="yddJ" downshifts 537614 /Source="Nicolas_upshifts" /id="D233" /incds=1 /nref=1 /ntot=15 /MaxReadThrough="6.32422" /MaxDrop="3.45679" /score="-2.67923628" /energy="-7.8" /TU="U383,U386" /idTUdmin="U382" /TUdmin=2662 /isTUend="FALSE" CDS 538061..538309 /gene="conC" /locus_tag="BSU_04920" /old_locus_tag="BSU04920" /function="18: Unknown function" /experiment="publication(s) with functional evidences, PMID:22505685, 26013486" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 22505685, 26013486; Product type h: extrachromosomal origin" /codon_start=1 /transl_table=11 /product="ICEBs1 mobile element: subunit of the conjugation machinery" /protein_id="NP_388373.1" /db_xref="EnsemblGenomes-Gn:BSU04920" /db_xref="EnsemblGenomes-Tr:CAB12299" /db_xref="GOA:P96640" /db_xref="SubtiList:BG12110" /db_xref="UniProtKB/Swiss-Prot:P96640" /translation="MDFMNFFILGADLPTLGGVKGWASDVVIQFITIVVMFIAAKNLM KLKMGGIIFVCCIGSAVTWVIKHWSEFSGWINALMEKL*" gene 538061..538309 /gene="conC" /locus_tag="BSU_04920" /old_locus_tag="BSU04920" CDS 538322..538846 /gene="conD" /locus_tag="BSU_04930" /old_locus_tag="BSU04930" /experiment="publication(s) with functional evidences, PMID:22505685, 26013486" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 22505685, 26013486; Product type h: extrachromosomal origin" /codon_start=1 /transl_table=11 /product="ICEBs1 mobile element: subunit of the conjugation machinery" /protein_id="NP_388374.1" /db_xref="EnsemblGenomes-Gn:BSU04930" /db_xref="EnsemblGenomes-Tr:CAB12300" /db_xref="GOA:P96641" /db_xref="InterPro:IPR025608" /db_xref="SubtiList:BG12111" /db_xref="UniProtKB/Swiss-Prot:P96641" /translation="MGRLVFNYRKAMREPKKIQQLTENYSLPFAVELIPAINYFIFVG LCFGFWYGVRMIFPHAFDNSYVIVIFGIPFFLTMLVTKIKPEGKNIYIYFFDFAKYYF FIKLPQKKYCNDRKIDLSNEKQIEFRKLVKVVDYSNETKNAYEGNTQEFAVNKNGRRV GVLPNKKQFDSYAK*" gene 538322..538846 /gene="conD" /locus_tag="BSU_04930" /old_locus_tag="BSU04930" CDS 538734..541229 /gene="conE" /locus_tag="BSU_04940" /old_locus_tag="BSU04940" /experiment="publication(s) with functional evidences, PMID:19734305, 19943900, 22505685, 26013486" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 19734305, 19943900, 22505685, 26013486; Product type h: extrachromosomal origin" /codon_start=1 /transl_table=11 /product="ICEBs1 mobile element: VirB4-like ATPase" /protein_id="NP_388375.3" /db_xref="EnsemblGenomes-Gn:BSU04940" /db_xref="EnsemblGenomes-Tr:CAB12301" /db_xref="GOA:P96642" /db_xref="InterPro:IPR016628" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG12112" /db_xref="UniProtKB/Swiss-Prot:P96642" /translation="MRLKTPMKAIHKNLLLTRTGDVWAYYRIKSNSIPMQNKEKVESY KKKWQHLFEEITSYEDFHLMMYPSEYELEKRFKDLETDIAADAMDVARYYNEETVRLL EQRLGRLTKYDFILGVKLKSSLVNISVELKDNILSFFNTATDTVVKMLGWEQNVSTSF FEKYEEVEETLANIMASVRGERLSETEMTYINRYHFVRGLKHQTNEESEIKDVRSITN TIIDPTDPSVLHLHSDQDEGYSAFVVIDEFLHNMSESDLFYEAQSLPFPVEVQMKIQT ESKSITKPALNLKRQQLKEEQKEQQSTGDRSDVSTVTSATMIRHLQDEIKKEDVHVMN WLSVIVVHGKTKKECVGKATIVKRHLKGAGITCRLPVADQLNLFYKMLPGEKLDITDK NWIQKTTQDGVAESLFAVNSDIGSKIGFFLGWVDRFQEHTDLESAIMSSRDFVLFHPF LANQQLKGSKTRSPHCLITGDTGNGKSYLAKLIFNYISMLNIKSLYIDPKKEMRKWIQ RVLNDEYIRENFPLYIAHLEKYNYITLDHENTHNWGALDPISFLPPMKAKELVQVIFE QVYDFKGKDDINTAFLRATSEVIDAKQKGEQVGSLDIIRKMQSHPEEAVQKAGDYLNE VVSDSILKLCIHDGSNPALSLEKRITILEVENMDLPDHAERLENYTISQLKSSAVMFA LGKFCELFGMNQDEQTVEFIDEAWIFTTSQQGKKVERQMRRIGRSYNNAEYFISQSTK DALKEEDSGNFGVAFAFDEPNEREEVLKWMNMEVTKDNKKMMESMFQGQCLFKDYYGR TSKISIECLFEEWQGALKTVEKKAVAYAEEKYL*" gene 538734..541229 /gene="conE" /locus_tag="BSU_04940" /old_locus_tag="BSU04940" CDS 541248..541574 /gene="yddF" /locus_tag="BSU_04950" /old_locus_tag="BSU04950" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 19943900, 22505685, 26013486; Producttype h: extrachromosomal origin" /codon_start=1 /transl_table=11 /product="ICEBs1 mobile element: conserved protein of unknown function" /protein_id="NP_388376.1" /db_xref="EnsemblGenomes-Gn:BSU04950" /db_xref="EnsemblGenomes-Tr:CAB12302" /db_xref="InterPro:IPR015055" /db_xref="SubtiList:BG12113" /db_xref="UniProtKB/Swiss-Prot:P96643" /translation="MEIAFLNSLVVTSPGFYKAEKITLDEVKQWLKHYDGRYKSFIGH KSTAQFLQKLLGIRIEQNRKTFRHMKYQKAICFSLYERYPENVLLTQRDLEKARYQFY LLTRLD*" gene 541248..541574 /gene="yddF" /locus_tag="BSU_04950" /old_locus_tag="BSU04950" CDS 541578..544025 /gene="conG" /locus_tag="BSU_04960" /old_locus_tag="BSU04960" /experiment="publication(s) with functional evidences, PMID:19943900, 22505685, 26013486" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 19943900, 22505685, 26013486; Product type h: extrachromosomal origin" /codon_start=1 /transl_table=11 /product="ICEBs1 mobile element: VirB6 subunit of the conjugation machinery" /protein_id="NP_388377.1" /db_xref="EnsemblGenomes-Gn:BSU04960" /db_xref="EnsemblGenomes-Tr:CAB12303" /db_xref="GOA:P96644" /db_xref="InterPro:IPR000515" /db_xref="SubtiList:BG12114" /db_xref="UniProtKB/Swiss-Prot:P96644" /translation="MVVMKKKRILIVSAIVLLFLTVASAVTVFSADGDTTTQPKVEKA GGVELKVKRFPISRYQANNEASDDLIKGAFVGLTNVTFSFAGNIVRVVDTGMDILYNL QPIDEFANSITNVSKTVYKTLKKNFGEALFIFTCAYVVYLFCVRGSVKEAMRRSILFI CVMVIGGLWMSNAGYYMKVLNALSVEAQGKLLTAGNGLVGIVQDEGNFADSSAIEKGK EMEGTVAVMRNLYFDIALMKPFLIVNFDETSEKKINEEDTDKGGLNRIDKLLSYKLSE DGEKDKKDYIKETEIDDYKNESMTSGNVFNQLGESFIAVVASIVIGIPFLALAFFNFL LQVVALVIVFFVPFAFILAYVPQLAYSGFVTLGRLGSVYLLKAMLGVIVLFVYVTCFI VDKLIPPNGFGMYLLNVAVLASILWIGFHKRDAIIKFVTAGKVVSVDNNMMENMRQNI VQPAWEQAKKIGGVWGNGGGVFTDFTKHFGGRKDGSNADGVTGAPSGGGNSPSGTAMG YDNTHAISRTPQKETANGIANHNSRSLKRNPQTLSKEQEKQKQKEAFANAKENKQQSH LARLRKDGINSPMLKDALNEGNEDLSKRAPILQDKKDESARTDQKEYVEQLLKQPNNQ QQTDDASLQHEEESTSNRAPVLQENEKDTERTDQKAYIYDEQNQNLETDQQQDFEVQK DDSVSNSEPVAQEKTAEIKRSDQKVMMNQPEPQLGFESPQSTKVENQPIANNERKIRP SEPAKVHSDGIRVDEKQAVAPAENKTVSREKQPSSQTIKRTEQSVNSFDQVSLNEIAR RSSSKVEDRLRRDERTR*" gene 541578..544025 /gene="conG" /locus_tag="BSU_04960" /old_locus_tag="BSU04960" CDS 544022..545011 /gene="cwlT" /locus_tag="BSU_04970" /old_locus_tag="BSU04970" /experiment="publication(s) with functional evidences, PMID:18305117, 22505685, 24532767, 26013486" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 18305117, 22505685, 24532767, 26013486; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="ICEBs1 mobile element: two-domain autolysin withN-acetylmuramidase and DL-endopeptidase activity VirB1" /protein_id="NP_388378.1" /db_xref="EnsemblGenomes-Gn:BSU04970" /db_xref="EnsemblGenomes-Tr:CAB12304" /db_xref="GOA:P96645" /db_xref="InterPro:IPR000064" /db_xref="InterPro:IPR023346" /db_xref="SubtiList:BG12115" /db_xref="UniProtKB/Swiss-Prot:P96645" /translation="MISKKVVLPLVFSAPFIFFFVLCIVVVMTISRENQVGDDFIGGG DGEYETVGIAPEVERFRAVFEKYARQEGVFDQVNIIMALTMQESGGRSLDIMQSSESI GLPPNSITDPERSIEVGIKHFKKVFKQAGGDVRLTLQAYNFGSGFIDYVKKNGGKYTK KLALDFSRLQAFKMGWKSYGDPSYVDHVMRYVKGSDKNVKPVKGSMDFYETVMKEALK YEGQPYAWGGSNPETGFDCSGLVQWSFAKAGITLPRTAQEQHGATKKISEKEATAGDL VFFGGTYEGKAITHVGIYVGNGRMFNSNDSGIQYSDLKSGYWRDHLVSFGRIK*" gene 544022..545011 /gene="cwlT" /locus_tag="BSU_04970" /old_locus_tag="BSU04970" CDS 545026..545532 /gene="yddI" /locus_tag="BSU_04980" /old_locus_tag="BSU04980" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 22505685; Product type h :extrachromosomal origin" /codon_start=1 /transl_table=11 /product="ICEBs1 mobile element: conserved protein of unknown function" /protein_id="NP_388379.1" /db_xref="EnsemblGenomes-Gn:BSU04980" /db_xref="EnsemblGenomes-Tr:CAB12305" /db_xref="GOA:P96646" /db_xref="SubtiList:BG12116" /db_xref="UniProtKB/Swiss-Prot:P96646" /translation="MKTHIAWASACLLLVMLTGFFTIGQQTYKIEKLKDKNEVLSEKI KELNHIESTSSASENKAFFEAFFNYSDIDIRYETVKKHTTGKGFDYAFPSRSDQKHTV SVQSELLSLESYSKPLDESHELFLNIVEVATTANSVTTNQVLIVQTTMKKEKDGWLVD NVQVKGNG*" gene 545026..545532 /gene="yddI" /locus_tag="BSU_04980" /old_locus_tag="BSU04980" promotor_-35 545535..545541 /Source="Nicolas_upshift_promotors" /id="U387" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.464535464535465" /psig="0.997002997002997" /xcortree=555 /SigmaFactorBS="ataatgtgcaggttaagggaaatggataaaaGGTGGAAaaga tcaatttgtTTGTTTATACTAAATATTGAaaaaggaggtaatgtttattttgaaaaac c" /listShort="yddJ" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 545555..545574 /Source="Nicolas_upshift_promotors" /id="U387" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.464535464535465" /psig="0.997002997002997" /xcortree=555 /SigmaFactorBS="ataatgtgcaggttaagggaaatggataaaaGGTGGAAaaga tcaatttgtTTGTTTATACTAAATATTGAaaaaggaggtaatgtttattttgaaaaac c" /listShort="yddJ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 545564 /Source="Nicolas_upshifts" /id="U387" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.464535464535465" /psig="0.997002997002997" /xcortree=555 /SigmaFactorBS="ataatgtgcaggttaagggaaatggataaaaGGTGGAAaaga tcaatttgtTTGTTTATACTAAATATTGAaaaaggaggtaatgtttattttgaaaaac c" /listShort="yddJ" /GFF_Attribute="listLong" CDS 545595..545975 /gene="yddJ" /locus_tag="BSU_04990" /old_locus_tag="BSU04990" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type lp: lipoprotein" /codon_start=1 /transl_table=11 /product="ICEBs1 mobile element: putative lipoprotein of unknown function" /protein_id="NP_388380.1" /db_xref="EnsemblGenomes-Gn:BSU04990" /db_xref="EnsemblGenomes-Tr:CAB12306" /db_xref="InterPro:IPR028075" /db_xref="SubtiList:BG12117" /db_xref="UniProtKB/Swiss-Prot:P96647" /translation="MKNLFIFLSLMMMFVLTACGGSKYDDAIDDVISQYKEHKGNDTE INIKRENAIVRVYEGGKYIQFAFYMPDNSSRELTTFKYYEKFGDKYEKMTDMPGNGEN DRLGLSKKTPDYEEVKGEETELEE*" gene 545595..545975 /gene="yddJ" /locus_tag="BSU_04990" /old_locus_tag="BSU04990" downshifts 545952 /Source="Nicolas_upshifts" /id="D234" /incds=0 /nref=167 /ntot=245 /MaxReadThrough="2.07932" /MaxDrop="5.51482" /score="8.08816145" /energy="-14.7" /TU="NA" /idTUdmin="U383" /TUdmin=0 /isTUend="TRUE" downshifts complement(546028) /Source="Nicolas_upshifts" /id="D235" /incds=0 /nref=51 /ntot=228 /MaxReadThrough="3.21157" /MaxDrop="4.80215" /score="-2.66780619" /energy="-18.7" /TU="U388" /idTUdmin="U388" /TUdmin="-110" /isTUend="FALSE" S_feature complement(546051..546165) /Source="Nicolas_S_feature" /locus_tag="new_546051_546165_c" /HighExp="LPhT, Lbtran, Mt0, HiTm, Lbexp, M40t45, M0t45, HPh, dia0, Mal" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S173" downshifts complement(546094) /Source="Nicolas_upshifts" /id="D236" /incds=0 /nref=1 /ntot=2 /MaxReadThrough="5.69722" /MaxDrop="4.64006" /score="-2.66780619" /energy="-18.7" /TU="U388" /idTUdmin="U388" /TUdmin="-176" /isTUend="FALSE" CDS complement(546166..546966) /gene="yddK" /locus_tag="BSU_05000" /old_locus_tag="BSU05000" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 22505685; Product type h :extrachromosomal origin" /codon_start=1 /transl_table=11 /product="ICEBs1 mobile element: conserved protein of unknown function" /protein_id="NP_388381.1" /db_xref="EnsemblGenomes-Gn:BSU05000" /db_xref="EnsemblGenomes-Tr:CAB12307" /db_xref="GOA:P96648" /db_xref="InterPro:IPR000157" /db_xref="InterPro:IPR035897" /db_xref="SubtiList:BG12118" /db_xref="UniProtKB/Swiss-Prot:P96648" /translation="MDTLKKLKFEANGIIGVLLDYSREPVLTNIIDQFRTSLESNDIE LIRYSLEQLKTWYARNRNEIYKNEFVFNEFEHHETENKIKKFLDELPVVDETEKSSIT HFSSDQNRELEKKIFISHSSKDKIVCNAFVELLEDIGVSSEDIIYTSSPYHGIPGDED IFEYLKKHLFKGAYVFYMLSDNYYDSVYCLNEMGATWVNSNNCSTFILPGFKGEIKGV IDKNKKAFSLEEPIDLFNLKEKILRMYDLTLEDKKWERIKAKFNTKLK*" gene complement(546166..546966) /gene="yddK" /locus_tag="BSU_05000" /old_locus_tag="BSU05000" promotor_-10 complement(547011..547030) /Source="Nicolas_upshift_promotors" /id="U388" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.762237762237762" /psig=1 /xcortree=2317 /SigmaFactorBS="tttatgaattacccaaacaatccagactgctttaaaataaGT AGttagaataggagtctATGTTATATAATTAGATATGaaatgtttacaaacaatggat t" /listShort="yddK, S173" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(547029) /Source="Nicolas_upshifts" /id="U388" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.762237762237762" /psig=1 /xcortree=2317 /SigmaFactorBS="tttatgaattacccaaacaatccagactgctttaaaataaGT AGttagaataggagtctATGTTATATAATTAGATATGaaatgtttacaaacaatggat t" /listShort="yddK, S173" /GFF_Attribute="listLong" promotor_-35 complement(547046..547049) /Source="Nicolas_upshift_promotors" /id="U388" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.762237762237762" /psig=1 /xcortree=2317 /SigmaFactorBS="tttatgaattacccaaacaatccagactgctttaaaataaGT AGttagaataggagtctATGTTATATAATTAGATATGaaatgtttacaaacaatggat t" /listShort="yddK, S173" /GFF_Attribute="listLong" /label="promotor_-35" CDS 547306..548481 /gene="rapI" /locus_tag="BSU_05010" /old_locus_tag="BSU05010" /EC_number="3.1.-.-" /experiment="publication(s) with functional evidences, PMID:16105942, 22505685, 23526881" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16105942, 22505685, 23526881; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="ICEBs1 mobile element: response regulator aspartate phosphatase" /protein_id="NP_388382.1" /db_xref="EnsemblGenomes-Gn:BSU05010" /db_xref="EnsemblGenomes-Tr:CAB12308" /db_xref="GOA:P96649" /db_xref="InterPro:IPR011990" /db_xref="InterPro:IPR013026" /db_xref="InterPro:IPR019734" /db_xref="PDB:4I1A" /db_xref="SubtiList:BG12119" /db_xref="UniProtKB/Swiss-Prot:P96649" /translation="MRGVFLDKDKIPYDLVTKKLNEWYTSIKNDQVEQAEIIKTEVEK ELLNMEENQDALLYYQLLEFRHEIMLSYMKSKEIEDLNNAYETIKEIEKQGQLTGMLE YYFYFFKGMYEFRRKELISAISAYRIAESKLSEVEDEIEKAEFFFKVSYVYYYMKQTY FSMNYANRALKIFREYEEYAVQTVRCQFIVAGNLIDSLEYERALEQFLKSLEISKESN IEHLIAMSHMNIGICYDELKEYKKASQHLILALEIFEKSKHSFLTKTLFTLTYVEAKQ QNYNVALIYFRKGRFIADKSDDKEYSAKFKILEGLFFSDGETQLIKNAFSYLASRKMF ADVENFSIEVADYFHEQGNLMLSNEYYRMSIEARRKIKKGEIIDENQPDSIGSSDFK* " gene 547306..548481 /gene="rapI" /locus_tag="BSU_05010" /old_locus_tag="BSU05010" promotor_-35 548161..548168 /Source="Nicolas_upshift_promotors" /id="U389" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp="0.994005994005994" /psig="0.994005994005994" /xcortree=2790 /SigmaFactorBS="aacaaaattataatgttgctttgatatacTTTAGGAAagggc gatttattGCCGATAAAAGTGATGATAaggaatactcagcgaaattcaaaatattaga g" /listShort="phrI, yddM, S174" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 548182..548200 /Source="Nicolas_upshift_promotors" /id="U389" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp="0.994005994005994" /psig="0.994005994005994" /xcortree=2790 /SigmaFactorBS="aacaaaattataatgttgctttgatatacTTTAGGAAagggc gatttattGCCGATAAAAGTGATGATAaggaatactcagcgaaattcaaaatattaga g" /listShort="phrI, yddM, S174" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 548192 /Source="Nicolas_upshifts" /id="U389" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp="0.994005994005994" /psig="0.994005994005994" /xcortree=2790 /SigmaFactorBS="aacaaaattataatgttgctttgatatacTTTAGGAAagggc gatttattGCCGATAAAAGTGATGATAaggaatactcagcgaaattcaaaatattaga g" /listShort="phrI, yddM, S174" /GFF_Attribute="listLong" promotor_-35 548389..548395 /Source="Nicolas_upshift_promotors" /id="U390" /multdbtbs="SigH" /comp="M8" /sig="SigGF" /pcomp="0.902097902097902" /psig="0.902097902097902" /xcortree=882 /SigmaFactorBS="agtcgctgattattttcatgaacaaggaaatttaatgctctc taatgaatattatCGTATGAgtattgaagcaagaCGAAAAATTAAAaaaggggagatt a" /listShort="phrI" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 548394 /Source="Nicolas_upshifts" /id="U390" /multdbtbs="SigH" /comp="M8" /sig="SigGF" /pcomp="0.902097902097902" /psig="0.902097902097902" /xcortree=882 /SigmaFactorBS="agtcgctgattattttcatgaacaaggaaatttaatgctctc taatgaatattatCGTATGAgtattgaagcaagaCGAAAAATTAAAaaaggggagatt a" /listShort="phrI" /GFF_Attribute="listLong" promotor_-10 548410..548421 /Source="Nicolas_upshift_promotors" /id="U390" /multdbtbs="SigH" /comp="M8" /sig="SigGF" /pcomp="0.902097902097902" /psig="0.902097902097902" /xcortree=882 /SigmaFactorBS="agtcgctgattattttcatgaacaaggaaatttaatgctctc taatgaatattatCGTATGAgtattgaagcaagaCGAAAAATTAAAaaaggggagatt a" /listShort="phrI" /GFF_Attribute="listLong" /label="promotor_-10" CDS 548438..548557 /gene="phrI" /locus_tag="BSU_05020" /old_locus_tag="BSU05020" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:16816200, 21908671, 22505685" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16816200, 21908671, 22505685; Product type r: regulator" /codon_start=1 /transl_table=11 /product="ICEBs1 mobile element: secreted regulator of theactivity of phosphatase RapI" /protein_id="NP_388383.1" /db_xref="EnsemblGenomes-Gn:BSU05020" /db_xref="EnsemblGenomes-Tr:CAB12309" /db_xref="SubtiList:BG12645" /db_xref="UniProtKB/Swiss-Prot:O31492" /translation="MKISRILLAAVILSSVFSITYLQSDHNTEIKVAADRVGA*" gene 548438..548557 /gene="phrI" /locus_tag="BSU_05020" /old_locus_tag="BSU05020" downshifts 548555 /Source="Nicolas_upshifts" /id="D237" /incds=0 /nref=46 /ntot=227 /MaxReadThrough="4.14733" /MaxDrop="5.8523" /score="15.7846721" /energy="-10.4" /TU="U389" /idTUdmin="U390" /TUdmin="-15" /isTUend="TRUE" CDS 548710..549651 /gene="yddM" /locus_tag="BSU_05030" /old_locus_tag="BSU05030" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 22505685; Product type h: extrachromosomal origin" /codon_start=1 /transl_table=11 /product="ICEBs1 mobile element: putative helicase" /protein_id="NP_388384.1" /db_xref="EnsemblGenomes-Gn:BSU05030" /db_xref="EnsemblGenomes-Tr:CAB12310" /db_xref="GOA:P96650" /db_xref="SubtiList:BG12120" /db_xref="UniProtKB/Swiss-Prot:P96650" /translation="MGENMFKKEKVTEYIWTILIPTIITFIISWVGSYYNGTSTVSIG QPTKVSGQYITPINISPYHDIKELRITFPQKLDVKQISSNEPINVKSDKNNIGVESNS TFEIAKIVENNSVQLLITTQKKLNDKEIRIDKNGNNISVNYESQIVNPAKKQLINLII TSSIYFIMLNILALIMNKRWDKYYAKMKNEIKEFEDNAKDLDKKSKKKSEELSELRKT LNQAFEETDRIKYHEKKKQILLLAKLNDYKKELTFWRNTIRKVLYELPDGDKKADKLI GTVTSSLKTYGTVEKNEHDYESLKVAAALLNDSDKRS*" gene 548710..549651 /gene="yddM" /locus_tag="BSU_05030" /old_locus_tag="BSU05030" S_feature 549652..549910 /Source="Nicolas_S_feature" /locus_tag="new_549652_549910" /HighExp="HPh, S1, Gly, LoTm, LPh, MG 120, GM-0.1, aero, S2, M9-exp" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.80510899999999996" /TUshortSig="SigD" /TUshortPSig="0.994" /TUlongSig="NA" /TUlongPSig="NA" /label="S174" S_feature complement(549923..550239) /Source="Nicolas_S_feature" /locus_tag="new_549923_550239_c" /HighExp="Diami, dia15, dia5, HPh, Etha, H2O2, Cold, LPh, C90, Paraq" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S175" downshifts 549952 /Source="Nicolas_upshifts" /id="D238" /incds=0 /nref=3 /ntot=115 /MaxReadThrough="0.144629999999999" /MaxDrop="3.58923" /score="4.45688042" /energy="-12.2" /TU="NA" /idTUdmin="U389" /TUdmin=84 /isTUend="FALSE" downshifts complement(549984) /Source="Nicolas_upshifts" /id="D239" /incds=0 /nref=3 /ntot=21 /MaxReadThrough="2.31925" /MaxDrop="3.67068" /score="-2.66780619" /energy="-18.7" /TU="NA" /idTUdmin="U391" /TUdmin=0 /isTUend="TRUE" CDS complement(550240..551259) /gene="yddN" /locus_tag="BSU_05040" /old_locus_tag="BSU05040" /EC_number="1.14.14.-" /function="16.8: Protect" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 9836433; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative alkanal monooxygenase" /protein_id="NP_388385.1" /db_xref="EnsemblGenomes-Gn:BSU05040" /db_xref="EnsemblGenomes-Tr:CAB12311" /db_xref="GOA:P96651" /db_xref="InterPro:IPR011251" /db_xref="InterPro:IPR019949" /db_xref="InterPro:IPR036661" /db_xref="SubtiList:BG12121" /db_xref="UniProtKB/Swiss-Prot:P96651" /translation="MKKFDISVLSVAPLRQGETMKQGIDSAVSLAKAVDNMGYKRIWF AEHHNHDAYASAATVSIVQHILANTKDIRVGSGGIMLPNHSPLIVAEQFGTLETLYPN RVDLALGRAPGTDQKTADVIRRSNHNGVFFFEREVNDILRFVGDKSVQGEVRAYPGIG THVPVFVLGSSTDSAEIAAKLGLPYAFGAQFSPHSMEEALSIYRENFQPSSYLQEPYV IACINVIAAESIDEASFISASHLQVYIDIYTNNLSKLIPPTENFLESLSQFELEILHS RLGYTIMGDRETIRRELIDFQQMYHADELIVLSNIYELSKEIQSYEILKQVVDELFKK RMEQL*" gene complement(550240..551259) /gene="yddN" /locus_tag="BSU_05040" /old_locus_tag="BSU05040" promotor_-10 complement(550935..550954) /Source="Nicolas_upshift_promotors" /id="U391" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.983016983016983" /psig="0.999000999001" /xcortree=1980 /SigmaFactorBS="ttccccattaatcgtagcggagcaatttggaaCACTTGAAac attatatccaaaTCGTGTAGATTTGGCATTAGgacgcgcacccggaacggatcaaaaa a" /listShort="S175" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(550948) /Source="Nicolas_upshifts" /id="U391" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.983016983016983" /psig="0.999000999001" /xcortree=1980 /SigmaFactorBS="ttccccattaatcgtagcggagcaatttggaaCACTTGAAac attatatccaaaTCGTGTAGATTTGGCATTAGgacgcgcacccggaacggatcaaaaa a" /listShort="S175" /GFF_Attribute="listLong" promotor_-35 complement(550969..550976) /Source="Nicolas_upshift_promotors" /id="U391" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.983016983016983" /psig="0.999000999001" /xcortree=1980 /SigmaFactorBS="ttccccattaatcgtagcggagcaatttggaaCACTTGAAac attatatccaaaTCGTGTAGATTTGGCATTAGgacgcgcacccggaacggatcaaaaa a" /listShort="S175" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 551048..551052 /Source="Nicolas_upshift_promotors" /id="U392" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.994005994005994" /psig=1 /xcortree=2543 /SigmaFactorBS="ttggcaacataataccccctgaacctacgcgaatgTCTTTtg tatttgctaatataTGTTGTACAATTGATACGGTtgctgcacttgcataagcgtcgtg a" /listShort="S176, lrpA, S177" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 551069..551088 /Source="Nicolas_upshift_promotors" /id="U392" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.994005994005994" /psig=1 /xcortree=2543 /SigmaFactorBS="ttggcaacataataccccctgaacctacgcgaatgTCTTTtg tatttgctaatataTGTTGTACAATTGATACGGTtgctgcacttgcataagcgtcgtg a" /listShort="S176, lrpA, S177" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 551073 /Source="Nicolas_upshifts" /id="U392" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.994005994005994" /psig=1 /xcortree=2543 /SigmaFactorBS="ttggcaacataataccccctgaacctacgcgaatgTCTTTtg tatttgctaatataTGTTGTACAATTGATACGGTtgctgcacttgcataagcgtcgtg a" /listShort="S176, lrpA, S177" /GFF_Attribute="listLong" S_feature 551074..551518 /Source="Nicolas_S_feature" /locus_tag="new_551074_551518" /HighExp="dia15, dia5, H2O2, G180, G135, Paraq, HPh, LBGexp, Lbexp, G150" /AntisenseName="yddN" /AntisenseCor="0.70327972625798696" /AntisenseRegPval="-40.700000000000003" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S176" CDS 551519..551929 /gene="lrpA" /locus_tag="BSU_05050" /old_locus_tag="BSU05050" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:11902725, 12675791, 17223133" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11902725, 12675791, 17223133; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator (Lrp/AsnC family)" /protein_id="NP_388386.1" /db_xref="EnsemblGenomes-Gn:BSU05050" /db_xref="EnsemblGenomes-Tr:CAB12312" /db_xref="GOA:P96652" /db_xref="InterPro:IPR000485" /db_xref="InterPro:IPR011008" /db_xref="InterPro:IPR019887" /db_xref="InterPro:IPR019888" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG12122" /db_xref="UniProtKB/Swiss-Prot:P96652" /translation="MIDEIDKKILDELSKNSRLTMKKLGEKVHLTAPATASRVVKLID NGIIKGCSIEVNQVKLGFSIHAFLNIYIEKIHHQPYLAFIETQDNYVINNYKVSGDGC YLLECKFPSNEVLDQFLNDLNKHANYKVSIVIGK*" gene 551519..551929 /gene="lrpA" /locus_tag="BSU_05050" /old_locus_tag="BSU05050" S_feature 551930..551999 /Source="Nicolas_S_feature" /locus_tag="new_551930_551999" /HighExp="dia15, dia5, H2O2, HPh, G180, G135, LBGtran, Paraq, dia0, Lbexp" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S177" downshifts 551956 /Source="Nicolas_upshifts" /id="D240" /incds=0 /nref=45 /ntot=194 /MaxReadThrough="2.99689" /MaxDrop="3.6808" /score="-1.98969146" /energy="-15.7" /TU="U392" /idTUdmin="U392" /TUdmin="-350" /isTUend="FALSE" CDS complement(552052..552501) /gene="lrpB" /locus_tag="BSU_05060" /old_locus_tag="BSU05060" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:11902725, 12675791, 17223133" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11902725, 12675791, 17223133; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator (Lrp/AsnC family)" /protein_id="NP_388387.1" /db_xref="EnsemblGenomes-Gn:BSU05060" /db_xref="EnsemblGenomes-Tr:CAB12313" /db_xref="GOA:P96653" /db_xref="InterPro:IPR000485" /db_xref="InterPro:IPR011008" /db_xref="InterPro:IPR019887" /db_xref="InterPro:IPR019888" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG12123" /db_xref="UniProtKB/Swiss-Prot:P96653" /translation="MQIDSIDFQILQLLNKNARIQWKEIGEKIHMTGQAVGNRIKKME DNGIIKAYSIVVDELKMGFSFTAFVFFFMNAYMHDDLLKFIATRNEISEAHRVSGDAC YLLKVTVHSQEVLNHLLNDLLKYGNYQLYLSIKEVKKHYNTSLMSDE*" gene complement(552052..552501) /gene="lrpB" /locus_tag="BSU_05060" /old_locus_tag="BSU05060" CDS 552616..553158 /gene="yddQ" /locus_tag="BSU_05070" /old_locus_tag="BSU05070" /EC_number="3.-.-.-" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative hydrolase" /protein_id="NP_388388.1" /db_xref="EnsemblGenomes-Gn:BSU05070" /db_xref="EnsemblGenomes-Tr:CAB12314" /db_xref="GOA:P96654" /db_xref="InterPro:IPR000868" /db_xref="InterPro:IPR036380" /db_xref="SubtiList:BG12124" /db_xref="UniProtKB/Swiss-Prot:P96654" /translation="MTTALLVIDIQNDYFPNGKMALTNPEKAAQNAAKLLSHFRNTGA PVFHVQHITEGNIAHFFHPNTEGVEIHESVRPLEKETVIVKHMPNSFFNTDLNGKLQE EGVKELVVCGMMSHMCIDATVRSAVEHGYVCQVVEDACATTTLQIEDKIVPAEHVHYA FMAALNGVYATVKTTEAFLK*" gene 552616..553158 /gene="yddQ" /locus_tag="BSU_05070" /old_locus_tag="BSU05070" promotor_-35 553631..553635 /Source="Nicolas_upshift_promotors" /id="U393" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.96003996003996" /psig="0.998001998001998" /xcortree=2688 /SigmaFactorBS="agtcaaagagttaaaacacttttttttatcTATGTattcgaa cactgctgaTATTATACACTTAACTCTGTcgatctaagacaaataaaaaaagaaagtg a" /listShort="yddR" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 553652..553671 /Source="Nicolas_upshift_promotors" /id="U393" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.96003996003996" /psig="0.998001998001998" /xcortree=2688 /SigmaFactorBS="agtcaaagagttaaaacacttttttttatcTATGTattcgaa cactgctgaTATTATACACTTAACTCTGTcgatctaagacaaataaaaaaagaaagtg a" /listShort="yddR" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 553661 /Source="Nicolas_upshifts" /id="U393" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.96003996003996" /psig="0.998001998001998" /xcortree=2688 /SigmaFactorBS="agtcaaagagttaaaacacttttttttatcTATGTattcgaa cactgctgaTATTATACACTTAACTCTGTcgatctaagacaaataaaaaaagaaagtg a" /listShort="yddR" /GFF_Attribute="listLong" CDS 553711..554475 /gene="yddR" /locus_tag="BSU_05080" /old_locus_tag="BSU05080" /EC_number="3.-.-.-" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative metal-dependent hydrolase" /protein_id="NP_388389.1" /db_xref="EnsemblGenomes-Gn:BSU05080" /db_xref="EnsemblGenomes-Tr:CAB12315" /db_xref="GOA:P96655" /db_xref="InterPro:IPR001279" /db_xref="InterPro:IPR036866" /db_xref="SubtiList:BG12125" /db_xref="UniProtKB/Swiss-Prot:P96655" /translation="MNITQIRNATIVVKYANKKFLIDPMLAEKGTYATFPETIRQDLF NPLVSLPTSIDNILDGVDAVIVTHLHLDHFDDVAKNVLPKNIKMFVQNEADAKEVKAS GFKNVEVLHQDTVFEGIQLVKTKGEHGRGEELLNLMGDVCGLVFKHPSEKVLYVAGDT VWYDAIEDEIHTHQPEIIVVNGGDNQRLDLGSLIMGKEDIYEVHKAAPHAKIISVHME AVNHWTLSREELKNFSKEKGFSSNILVPEDGESYTF*" gene 553711..554475 /gene="yddR" /locus_tag="BSU_05080" /old_locus_tag="BSU05080" CDS 554669..555979 /gene="yddS" /locus_tag="BSU_05090" /old_locus_tag="BSU05090" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative permease" /protein_id="NP_388390.1" /db_xref="EnsemblGenomes-Gn:BSU05090" /db_xref="EnsemblGenomes-Tr:CAB12316" /db_xref="GOA:P96656" /db_xref="InterPro:IPR005828" /db_xref="InterPro:IPR011701" /db_xref="InterPro:IPR020846" /db_xref="InterPro:IPR036259" /db_xref="SubtiList:BG12126" /db_xref="UniProtKB/Swiss-Prot:P96656" /translation="MVMTKKDTNISTQQPLWLQGYIDSPEKQNQLYKKTLKILIFSQI FGGAGLGAGITVGALLAQDMIGSENVAGIPTALFTFGSAVAALLIGASSQRFGRRAGL AGGFLIGGLGAIGVIIAALINSVALLFVSLLIYGAGMASNLQVRYAGTDLANEKQRAT AASMALVSTTLGAVVGPNLVNTMGEFADSIGVPNLAGPFIMSGAAFIIAGIILLIFLR PDPLFVSTAIANAEKKDDKVQIGGSLKNPAIDKKGIMVGAVIMILAQLIMTAIMTMTP VHMGHHGHGLSEVGLVIGLHIAAMYLPSPLTGLLVDKFGRTTMAIASGATLLAAGLVA AIAPADSLSLLILALVLLGVGWNFGLLTGTALIIDSTHPSLRAKTQGTFDVLLALSGA AGGALSGMVVAHSSYTILSISGAVLSLLLIPVVIWYFRRIQEKA*" gene 554669..555979 /gene="yddS" /locus_tag="BSU_05090" /old_locus_tag="BSU05090" S_feature 556002..556561 /Source="Nicolas_S_feature" /locus_tag="new_556002_556561" /HighExp="S8, C30, Cold, BMM, C90, GM 25, MG 15, M/G, LPh, S7" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="NA" /TUshortPSig="NA" /TUlongSig="NA" /TUlongPSig="NA" /label="S178" CDS 556562..556738 /gene="ydzM" /locus_tag="BSU_05099" /old_locus_tag="BSU05099" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; Product type h: extrachromosomal origin" /codon_start=1 /transl_table=11 /product="conserved phage protein of unknown function" /protein_id="YP_003097682.1" /db_xref="EnsemblGenomes-Gn:BSU05099" /db_xref="EnsemblGenomes-Tr:CAX52553" /db_xref="GOA:Q9K3A9" /db_xref="UniProtKB/Swiss-Prot:Q9K3A9" /translation="MNNKKNIFDIVMYIIFGVLSLFLVAKTDYGTGVLVFVAILYLAV IAYKIKQVFSNSDS*" gene 556562..556738 /gene="ydzM" /locus_tag="BSU_05099" /old_locus_tag="BSU05099" CDS 556763..557449 /gene="yddT" /locus_tag="BSU_05100" /old_locus_tag="BSU05100" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type h : extrachromosomal origin" /codon_start=1 /transl_table=11 /product="putative exported phage protein" /protein_id="NP_388391.1" /db_xref="EnsemblGenomes-Gn:BSU05100" /db_xref="EnsemblGenomes-Tr:CAB12317" /db_xref="SubtiList:BG12127" /db_xref="UniProtKB/Swiss-Prot:P96657" /translation="MRKKRVITCVMAASLTLGSLLPAGYASAKEDSKTTPSYEELALH YKMKSEKISSNGKLVEIEYVSGNETHKVQMNGNNHTVKVDGIEQKGLNFEYDENVAKR TNYENNNLKSNEFTTQAAKPKKGYHYVGTLSGHTKAAKNALSVTMSLVGIVPGLGWGS KAATILFSYWAKEQIPDAYYKYDLYEKGAMTDSWYQYATVQFFEDKAHKKKMGKPWTS TPAKVDLPNS*" gene 556763..557449 /gene="yddT" /locus_tag="BSU_05100" /old_locus_tag="BSU05100" promotor_-35 557791..557795 /Source="Nicolas_upshift_promotors" /id="U394" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.383616383616384" /psig="0.999000999001" /xcortree=2778 /SigmaFactorBS="gaaaggtttaagattagatattgaaaaattttaTATATtttc aataaaatacTGGTACTATAATAAATGTATacagattgtatggagatgtaattaatta a" /listShort="ydzN, ydeA" /listLong="S179, cspC" /label="promotor_-35" promotor_-10 557810..557829 /Source="Nicolas_upshift_promotors" /id="U394" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.383616383616384" /psig="0.999000999001" /xcortree=2778 /SigmaFactorBS="gaaaggtttaagattagatattgaaaaattttaTATATtttc aataaaatacTGGTACTATAATAAATGTATacagattgtatggagatgtaattaatta a" /listShort="ydzN, ydeA" /listLong="S179, cspC" /label="promotor_-10" upshifts 557818 /Source="Nicolas_upshifts" /id="U394" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.383616383616384" /psig="0.999000999001" /xcortree=2778 /SigmaFactorBS="gaaaggtttaagattagatattgaaaaattttaTATATtttc aataaaatacTGGTACTATAATAAATGTATacagattgtatggagatgtaattaatta a" /listShort="ydzN, ydeA" /listLong="S179, cspC" CDS 557873..558058 /gene="ydzN" /locus_tag="BSU_05109" /old_locus_tag="BSU05109" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_003097683.1" /db_xref="EnsemblGenomes-Gn:BSU05109" /db_xref="EnsemblGenomes-Tr:CAX52554" /db_xref="GOA:C0H3V7" /db_xref="UniProtKB/Swiss-Prot:C0H3V7" /translation="MRWSKWFNVFCIVALGSIYGYKLFTNQEVSTTRLIIASVIVLWN IVGLFSKESVKQAQQAN*" gene 557873..558058 /gene="ydzN" /locus_tag="BSU_05109" /old_locus_tag="BSU05109" downshifts 558057 /Source="Nicolas_upshifts" /id="D241" /incds=0 /nref=9 /ntot=125 /MaxReadThrough="3.39785" /MaxDrop="3.7067" /score="-6.31330934" /energy="-12.8" /TU="U394" /idTUdmin="U394" /TUdmin="-1068" /isTUend="FALSE" CDS 558408..559001 /gene="sufLC" /locus_tag="BSU_05110" /old_locus_tag="BSU05110" /experiment="publication(s) with functional evidences, PMID:24330391" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 24330391; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="glyoxalase III homolog, deglycase" /protein_id="NP_388392.1" /db_xref="EnsemblGenomes-Gn:BSU05110" /db_xref="EnsemblGenomes-Tr:CAB12318" /db_xref="GOA:P96658" /db_xref="InterPro:IPR002818" /db_xref="InterPro:IPR029062" /db_xref="PDB:3F5D" /db_xref="SubtiList:BG12128" /db_xref="UniProtKB/Swiss-Prot:P96658" /translation="MKKALFLILDQYADWEGVYLASALNQREDWSVHTVSLDPIVSSI GGFKTSVDYIIGLEPANFNLLVMIGGDSWSNDNKKLLHFVKTAFQKNIPIAAICGAVD FLAKNGLLNNHSHTGNFVYLWKDYKQYKPISSFVEKQAVRDKNLVTANGTAPIEFTNL ILEMIDFDTPENIEKMMYMNRYGFYHFCDKYGNPFVD*" gene 558408..559001 /gene="sufLC" /locus_tag="BSU_05110" /old_locus_tag="BSU05110" promotor_-35 559114..559121 /Source="Nicolas_upshift_promotors" /id="U395" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.561438561438561" /psig=1 /xcortree=3090 /SigmaFactorBS="aagtttaacaaataatgccatcaatattAATTTGCAgttatt tccgattCCTGATATAATAAAGAAGAAttatttttgttcggtgtaaaggatagtatga a" /listShort="S179, cspC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 559135..559154 /Source="Nicolas_upshift_promotors" /id="U395" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.561438561438561" /psig=1 /xcortree=3090 /SigmaFactorBS="aagtttaacaaataatgccatcaatattAATTTGCAgttatt tccgattCCTGATATAATAAAGAAGAAttatttttgttcggtgtaaaggatagtatga a" /listShort="S179, cspC" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 559146..559263 /Source="Nicolas_S_feature" /locus_tag="new_559146_559263" /HighExp="B60, LoTm, T5.0H, T3.30H, M9-stat, BI, BC, C90, T3.0H, Cold" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="SigA" /TUlongPSig="0.999" /label="S179" upshifts 559146 /Source="Nicolas_upshifts" /id="U395" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.561438561438561" /psig=1 /xcortree=3090 /SigmaFactorBS="aagtttaacaaataatgccatcaatattAATTTGCAgttatt tccgattCCTGATATAATAAAGAAGAAttatttttgttcggtgtaaaggatagtatga a" /listShort="S179, cspC" /GFF_Attribute="listLong" downshifts complement(559181) /Source="Nicolas_upshifts" /id="D242" /incds=0 /nref=10 /ntot=93 /MaxReadThrough="1.86628" /MaxDrop="4.19111" /score="25.1917407" /energy="-12.9" /TU="NA" /idTUdmin="U396" /TUdmin=328 /isTUend="FALSE" CDS 559264..559464 /gene="cspC" /locus_tag="BSU_05120" /old_locus_tag="BSU05120" /function="16.6: Maintain" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:9379903, 9914312, 9920884, 10517332, 11591689, 12427936" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9379903, 9914312, 9920884, 10517332, 11591689, 12427936; Product type f : factor" /codon_start=1 /transl_table=11 /product="cold-shock protein" /protein_id="NP_388393.1" /db_xref="EnsemblGenomes-Gn:BSU05120" /db_xref="EnsemblGenomes-Tr:CAB12319" /db_xref="GOA:P39158" /db_xref="InterPro:IPR002059" /db_xref="InterPro:IPR011129" /db_xref="InterPro:IPR012156" /db_xref="InterPro:IPR012340" /db_xref="InterPro:IPR019844" /db_xref="SubtiList:BG11024" /db_xref="UniProtKB/Swiss-Prot:P39158" /translation="MEQGTVKWFNAEKGFGFIERENGDDVFVHFSAIQSDGFKSLDEG QKVSFDVEQGARGAQAANVQKA*" gene 559264..559464 /gene="cspC" /locus_tag="BSU_05120" /old_locus_tag="BSU05120" S_feature complement(559362..560150) /Source="Nicolas_S_feature" /locus_tag="new_559362_560150_c" /HighExp="LoTm, B60, Cold, M9-stat, LPhT, B36, Sw, BC, S8, Salt" /AntisenseName="cspC" /AntisenseCor="0.39074308987975698" /AntisenseRegPval="-10.5" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S180" downshifts 559367 /Source="Nicolas_upshifts" /id="D243" /incds=1 /nref=19 /ntot=179 /MaxReadThrough="8.05368" /MaxDrop="3.4464" /score="27.3387234" /energy="-11.3" /TU="U395" /idTUdmin="U394" /TUdmin=242 /isTUend="FALSE" downshifts 559468 /Source="Nicolas_upshifts" /id="D244" /incds=0 /nref=65 /ntot=246 /MaxReadThrough="5.78621" /MaxDrop="5.83905" /score="27.3387234" /energy="-11.3" /TU="U395" /idTUdmin="U394" /TUdmin=343 /isTUend="FALSE" misc_RNA complement(559532..559610) /gene="sncZ" /locus_tag="BSU_misc_RNA_66" /product="putative small conserved untranslated RNA" /experiment="publication(s) with functional evidences, PMID:20525796" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 20525796; Product type n: RNA" gene complement(559532..559610) /gene="sncZ" /locus_tag="BSU_misc_RNA_66" CDS complement(560151..560612) /gene="cdnL" /locus_tag="BSU_05130" /old_locus_tag="BSU05130" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1c: Function from experimental evidences in the studied genus; PubMedId: 26849219; Product type r : regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator for repair and outgrowth of heat damaged spores" /protein_id="NP_388394.1" /db_xref="EnsemblGenomes-Gn:BSU05130" /db_xref="EnsemblGenomes-Tr:CAB12320" /db_xref="InterPro:IPR003711" /db_xref="InterPro:IPR036101" /db_xref="SubtiList:BG12129" /db_xref="UniProtKB/Swiss-Prot:P96659" /translation="MFQIGDNIVYPMHGAGIIEAIEEKEFLEEKQQYYVIRMSISNMT VMIPTSKILSSNIRPVTDILALKHIMHIFQHGESDRLLPWKQRYKINTDKIKTGEIQE GAEVVRDLMRMKKEKALNASEKKMLDNAYEFLISELEVIKGITEKQIKSFG*" gene complement(560151..560612) /gene="cdnL" /locus_tag="BSU_05130" /old_locus_tag="BSU05130" S_feature 560621..561166 /Source="Nicolas_S_feature" /locus_tag="new_560621_561166" /HighExp="Cold, G135, S8, G180, LoTm, S7, G150, HPh, Paraq, Oxctl" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="NA" /TUshortPSig="NA" /TUlongSig="NA" /TUlongPSig="NA" /label="S181" upshifts complement(560664) /Source="Nicolas_upshifts" /id="U396" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.756243756243756" /psig=1 /xcortree=427 /SigmaFactorBS="ttcaaaaaagtTATTGACAtcaaaaattcgatcaTGTTATTA TTAAAATTTTGAtattacacctccatatatggtaatcttaagaaggataccatatatg g" /listShort="ydeB, S180" /GFF_Attribute="listLong" promotor_-10 complement(560671..560690) /Source="Nicolas_upshift_promotors" /id="U396" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.756243756243756" /psig=1 /xcortree=427 /SigmaFactorBS="ttcaaaaaagtTATTGACAtcaaaaattcgatcaTGTTATTA TTAAAATTTTGAtattacacctccatatatggtaatcttaagaaggataccatatatg g" /listShort="ydeB, S180" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 complement(560706..560713) /Source="Nicolas_upshift_promotors" /id="U396" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.756243756243756" /psig=1 /xcortree=427 /SigmaFactorBS="ttcaaaaaagtTATTGACAtcaaaaattcgatcaTGTTATTA TTAAAATTTTGAtattacacctccatatatggtaatcttaagaaggataccatatatg g" /listShort="ydeB, S180" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 561133 /Source="Nicolas_upshifts" /id="D245" /incds=0 /nref=7 /ntot=141 /MaxReadThrough="0.289110000000001" /MaxDrop="4.3701" /score="26.1823933" /energy="-9.5" /TU="NA" /idTUdmin="U395" /TUdmin=864 /isTUend="FALSE" CDS complement(561180..561416) /gene="ydzE" /locus_tag="BSU_05140" /old_locus_tag="BSU05140" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative permease" /protein_id="NP_388395.1" /db_xref="EnsemblGenomes-Gn:BSU05140" /db_xref="EnsemblGenomes-Tr:CAB12321" /db_xref="GOA:O31493" /db_xref="InterPro:IPR000620" /db_xref="SubtiList:BG12808" /db_xref="UniProtKB/Swiss-Prot:O31493" /translation="MYLGIVSTACAFLLWNHGLQLLNASSGGLFFFFQPLVGTLLGWI LLGEQIGGTFWIGSFLILSGVLLVIKEKEKEVKS*" gene complement(561180..561416) /gene="ydzE" /locus_tag="BSU_05140" /old_locus_tag="BSU05140" CDS complement(561514..562389) /gene="ydeC" /locus_tag="BSU_05150" /old_locus_tag="BSU05150" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 10704478; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative transcriptional regulator (AraC/XylS family)" /protein_id="NP_388396.1" /db_xref="EnsemblGenomes-Gn:BSU05150" /db_xref="EnsemblGenomes-Tr:CAB12322" /db_xref="GOA:P96660" /db_xref="InterPro:IPR003313" /db_xref="InterPro:IPR009057" /db_xref="InterPro:IPR014710" /db_xref="InterPro:IPR018060" /db_xref="InterPro:IPR018062" /db_xref="InterPro:IPR020449" /db_xref="SubtiList:BG12130" /db_xref="UniProtKB/Swiss-Prot:P96660" /translation="MKNFVIDQNLKELTEHRTVELPVACYKTTINQNINGYIPLHWHD EIQFVLILKGIALFQINEEKIEVHEGDGLFINSGYLHMAEEKEGSDCTYICLNVSPHF VLSQELYSSYVQPYMFSTNLPYLFLAGNQQWAKNILDAVKKINQLIQQKTSLYEIDIT MQLTLMWKNLVVNGFQLEYDQSEMIKSHRMKQMLNWIHLHYVEKITLEDIAKAGQLSR SECCRYFKRMLNKTPLRYVMDYRIQKSLLLLQHPESNVTEVSYQVGFNSTSYFISKFQ QAMNMTPLSYKKMNS*" gene complement(561514..562389) /gene="ydeC" /locus_tag="BSU_05150" /old_locus_tag="BSU05150" CDS 562502..563461 /gene="ydeD" /locus_tag="BSU_05160" /old_locus_tag="BSU05160" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative permease" /protein_id="NP_388397.1" /db_xref="EnsemblGenomes-Gn:BSU05160" /db_xref="EnsemblGenomes-Tr:CAB12323" /db_xref="GOA:P96661" /db_xref="InterPro:IPR000620" /db_xref="SubtiList:BG12131" /db_xref="UniProtKB/Swiss-Prot:P96661" /translation="MNTSNRRMGLFYVITGATCWGIGGTVAKKLFQEYQIDVNWLVTT RLLTAGMLLLMLQLFRKDRSQVIEVWKHKASAGQLLIFGLLGMLAVQYTYMASIQHGN AAVATLLQYLSPVIVIIYTLLRKQTVLTKQDIITVVLALVGCFFLLTNGSMSQLSVPA AAVVWGVLSGFAAAFYTLYAVGLLNKFDSLVVVGWAMIIGGFALGFIHPPWQLDFQRL TAEAYAYILFVILFGTMIAFWFFIKSLESLSPKETSLLGSLEPLSAVVTTVVWLKAPF GSFQWIGAICIIGITLILALHKEPSMESEKSILKIRNHANRDI*" gene 562502..563461 /gene="ydeD" /locus_tag="BSU_05160" /old_locus_tag="BSU05160" upshifts complement(562523) /Source="Nicolas_upshifts" /id="U397" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.555444555444555" /psig="0.808191808191808" /xcortree=1969 /SigmaFactorBS="tggctactgtgcctccaatcccccaacatgtcgccccTGTGA TAACATAGAACAATCccattcttctattggaagtattcatacatgactcctcactaat a" /listShort="ydeC" /GFF_Attribute="listLong" misc_feature complement(562527..562546) /Source="Nicolas_upshift_promotors" /id="U397" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.555444555444555" /psig="0.808191808191808" /xcortree=1969 /SigmaFactorBS="tggctactgtgcctccaatcccccaacatgtcgccccTGTGA TAACATAGAACAATCccattcttctattggaagtattcatacatgactcctcactaat a" /listShort="ydeC" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" CDS complement(563614..564486) /gene="ydeE" /locus_tag="BSU_05170" /old_locus_tag="BSU05170" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative transcriptional regulator (AraC/XylS family)" /protein_id="NP_388398.1" /db_xref="EnsemblGenomes-Gn:BSU05170" /db_xref="EnsemblGenomes-Tr:CAB12324" /db_xref="GOA:P96662" /db_xref="InterPro:IPR009057" /db_xref="InterPro:IPR010499" /db_xref="InterPro:IPR011256" /db_xref="InterPro:IPR018060" /db_xref="InterPro:IPR018062" /db_xref="InterPro:IPR020449" /db_xref="InterPro:IPR029442" /db_xref="SubtiList:BG12132" /db_xref="UniProtKB/Swiss-Prot:P96662" /translation="MDLLKSMNRALKYIEENLTNDIDFQEAAKLAFCSEYHFKRMFSF LAGISLSEYIRRRRLTLAAFELKDSNVKVIDIAIKYGYNSPDSFARAFQNLHGINPSK ARFNGHSLKAYPRMTFQLTIKGGNEMNYRIEEKEAFRIVGIKKRVPIIFKGINPEIAS MWESLDEKAINKLKELSNVAPSGLISASTNFSEGRTEENGELDHYIGAATTKRCPDNF SRLEVPASTWAVFESIGPFPDTLQEVWGRIYSEWFPSSNYEQIEGPEILWNEHKDVTS PSFKSEIWIPITKK*" gene complement(563614..564486) /gene="ydeE" /locus_tag="BSU_05170" /old_locus_tag="BSU05170" promotor_-10 complement(564579..564584) /Source="Nicolas_upshift_promotors" /id="U398" /multdbtbs="-" /comp="M3" /sig="Sig-" /pcomp="0.380619380619381" /psig="0.432567432567433" /xcortree=1464 /SigmaFactorBS="cttttattgatgcctttttatgaacagcatgcttcaataaaa cctgtacaaatacaagtgaatcACtTACTTTatttcatataagtcatcctgcaaaact g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 complement(564586..564587) /Source="Nicolas_upshift_promotors" /id="U398" /multdbtbs="-" /comp="M3" /sig="Sig-" /pcomp="0.380619380619381" /psig="0.432567432567433" /xcortree=1464 /SigmaFactorBS="cttttattgatgcctttttatgaacagcatgcttcaataaaa cctgtacaaatacaagtgaatcACtTACTTTatttcatataagtcatcctgcaaaact g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" upshifts complement(564591) /Source="Nicolas_upshifts" /id="U398" /multdbtbs="-" /comp="M3" /sig="Sig-" /pcomp="0.380619380619381" /psig="0.432567432567433" /xcortree=1464 /SigmaFactorBS="cttttattgatgcctttttatgaacagcatgcttcaataaaa cctgtacaaatacaagtgaatcACtTACTTTatttcatataagtcatcctgcaaaact g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 564660..564666 /Source="Nicolas_upshift_promotors" /id="U399" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.408591408591409" /psig="0.98101898101898" /xcortree=1860 /SigmaFactorBS="attgaagcatgctgttcataaaaaggcatcaataaaagaaag ttatAATTGTCttataaacggcacATTCATATAATTGAGTGAAAaaggatgcgtatca t" /listShort="ydeF" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 564674 /Source="Nicolas_upshifts" /id="U399" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.408591408591409" /psig="0.98101898101898" /xcortree=1860 /SigmaFactorBS="attgaagcatgctgttcataaaaaggcatcaataaaagaaag ttatAATTGTCttataaacggcacATTCATATAATTGAGTGAAAaaggatgcgtatca t" /listShort="ydeF" /GFF_Attribute="listLong" promotor_-10 564680..564699 /Source="Nicolas_upshift_promotors" /id="U399" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.408591408591409" /psig="0.98101898101898" /xcortree=1860 /SigmaFactorBS="attgaagcatgctgttcataaaaaggcatcaataaaagaaag ttatAATTGTCttataaacggcacATTCATATAATTGAGTGAAAaaggatgcgtatca t" /listShort="ydeF" /GFF_Attribute="listLong" /label="promotor_-10" CDS 564713..566101 /gene="ydeF" /locus_tag="BSU_05180" /old_locus_tag="BSU05180" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15223311, 28348215; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative PLP-dependent transcriptional regulator" /protein_id="NP_388399.2" /db_xref="EnsemblGenomes-Gn:BSU05180" /db_xref="EnsemblGenomes-Tr:CAB12325" /db_xref="GOA:P96663" /db_xref="InterPro:IPR000524" /db_xref="InterPro:IPR004839" /db_xref="InterPro:IPR015421" /db_xref="InterPro:IPR015422" /db_xref="InterPro:IPR015424" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG12133" /db_xref="UniProtKB/Swiss-Prot:P96663" /translation="MPINSFENYPMSWKPSIDKAEKPIYKALAGQLEQDILNGVLLPG TKLPPQRELADYLDLNVSTISKAFKVCELKGLLSATVGSGTFVSYDALSNAYLLEDTK PTHLIEMGAILPDHASYEPLLYQLKNMVHEEDYEKWFSYGRAGESLWQKDAAVKLIQR GGFETSVDHILFANGGQNAIAATLASLCKPGDRIGVDHHTYPGLKTVASLLSVQIVPI KSENDEMSPESLEYACKNENIKGLYLIPDYHNPTTSFMSVENRRMVADIVKKYNLFVI EDASYHLLNKNPLPALASFAPQQVIHIASLSKSLAPGLRLAYVAVPRQYKEPISKALY NLNITVSPLLAELTARTIVSNQFEVLIESHREQTIRRNQLVNRYVAGYTCLGVETGIF RWLLLPGKMSGAEFEELAARLGVQVYAAERFVVGNSCPERAVRVSVCAPKTLEELEQG LMILRRLLDDLT*" gene 564713..566101 /gene="ydeF" /locus_tag="BSU_05180" /old_locus_tag="BSU05180" downshifts 566077 /Source="Nicolas_upshifts" /id="D246" /incds=0 /nref=2 /ntot=61 /MaxReadThrough="0.91547" /MaxDrop="3.65963" /score="12.298375" /energy="-12.2" /TU="NA" /idTUdmin="U399" /TUdmin=176 /isTUend="FALSE" CDS 566211..567503 /gene="ydeG" /locus_tag="BSU_05190" /old_locus_tag="BSU05190" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative permease" /protein_id="NP_388400.1" /db_xref="EnsemblGenomes-Gn:BSU05190" /db_xref="EnsemblGenomes-Tr:CAB12326" /db_xref="GOA:P96664" /db_xref="InterPro:IPR011701" /db_xref="InterPro:IPR020846" /db_xref="InterPro:IPR036259" /db_xref="SubtiList:BG12134" /db_xref="UniProtKB/Swiss-Prot:P96664" /translation="MMLDKDSVKAIDVQTASLQSYISSPEKQKSLYKRTLFVVSISQI FGGAGLAAGVTVGALIAQQMLGTDAFAGLPSALFTLGSAGSALIVGRLSQRYGRRTGL SAGFMIGGLGAIGVIMAAIINSIFLLFISLLIYGAGTATNLQARYAGTDLANHKQRAT AVSITMVFTTFGAVAGPSLVNVMGDFALSIGVPSLAGPFILAAAAYMLAGVVLFIMLR PDPLVIARTIEAANEEPGDKGHLAATEHTENKKGIIVGATVMVLTQIVMVAIMTMTPV HMRHHGHDLGAVGLVIGFHIGAMYLPSLVTGVLVDRLGRTAMAISSGTTLLLAGVIAA FAPGESMILLVIALSLLGLGWNFGLISGTALIVDSTDTATRAKTQGTVDVLIALSGAA GGALSGMIVAGSSYLALSLIGGILSLLLIPVVVWSRGR*" gene 566211..567503 /gene="ydeG" /locus_tag="BSU_05190" /old_locus_tag="BSU05190" promotor_-35 567512..567518 /Source="Nicolas_upshift_promotors" /id="U400" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.737262737262737" /psig=1 /xcortree=2927 /SigmaFactorBS="gtggtatggtctaggggccgctaaagggtaggATTGTTTaat ttacattaattTGTTATATTGTTAGATAAAGtatattgcagcatctaatattctaacg a" /listShort="S182, ydeH" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 567533..567552 /Source="Nicolas_upshift_promotors" /id="U400" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.737262737262737" /psig=1 /xcortree=2927 /SigmaFactorBS="gtggtatggtctaggggccgctaaagggtaggATTGTTTaat ttacattaattTGTTATATTGTTAGATAAAGtatattgcagcatctaatattctaacg a" /listShort="S182, ydeH" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 567540 /Source="Nicolas_upshifts" /id="U400" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.737262737262737" /psig=1 /xcortree=2927 /SigmaFactorBS="gtggtatggtctaggggccgctaaagggtaggATTGTTTaat ttacattaattTGTTATATTGTTAGATAAAGtatattgcagcatctaatattctaacg a" /listShort="S182, ydeH" /GFF_Attribute="listLong" S_feature 567551..567661 /Source="Nicolas_S_feature" /locus_tag="new_567551_567661" /HighExp="LoTm, T4.0H, T3.30H, T2.30H, T3.0H, T2.0H, T1.30H, T5.0H, T1.0H, T-0.40H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S182" CDS 567662..568108 /gene="ydeH" /locus_tag="BSU_05200" /old_locus_tag="BSU05200" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative integral inner membrane protein" /protein_id="NP_388401.1" /db_xref="EnsemblGenomes-Gn:BSU05200" /db_xref="EnsemblGenomes-Tr:CAB12327" /db_xref="GOA:P96665" /db_xref="SubtiList:BG12135" /db_xref="UniProtKB/Swiss-Prot:P96665" /translation="MNHIKWLSDLKKAGLLALGKGVITLLKRFSLVIVTLMMSIVVVL AAAKESPGDHVISFDEPIILMISIGIVVFLLIPPLVMSFFGNLVVRIISGVYQCFIVF TFLGLIPIGFLIPNGFLTILVSIAGTLVSIASVAVTLCIGKNKKDI*" gene 567662..568108 /gene="ydeH" /locus_tag="BSU_05200" /old_locus_tag="BSU05200" downshifts 568137 /Source="Nicolas_upshifts" /id="D247" /incds=0 /nref=200 /ntot=251 /MaxReadThrough="2.56495" /MaxDrop="6.50538" /score="-1.7193297" /energy="-4.5" /TU="NA" /idTUdmin="U400" /TUdmin="-8" /isTUend="TRUE" promotor_-35 568188..568195 /Source="Nicolas_upshift_promotors" /id="U401" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.921078921078921" /psig="0.99100899100899" /xcortree=2390 /SigmaFactorBS="tacaaaaagagaaggcttgtgggccttctttttttgtTGTTG CATcatccccactttgaGCTTAATCTATTGAATAATAagagaaggaacctatagaaga a" /listShort="ydeI" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 568210..568229 /Source="Nicolas_upshift_promotors" /id="U401" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.921078921078921" /psig="0.99100899100899" /xcortree=2390 /SigmaFactorBS="tacaaaaagagaaggcttgtgggccttctttttttgtTGTTG CATcatccccactttgaGCTTAATCTATTGAATAATAagagaaggaacctatagaaga a" /listShort="ydeI" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 568211 /Source="Nicolas_upshifts" /id="U401" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.921078921078921" /psig="0.99100899100899" /xcortree=2390 /SigmaFactorBS="tacaaaaagagaaggcttgtgggccttctttttttgtTGTTG CATcatccccactttgaGCTTAATCTATTGAATAATAagagaaggaacctatagaaga a" /listShort="ydeI" /GFF_Attribute="listLong" CDS 568345..568938 /gene="ydeI" /locus_tag="BSU_05210" /old_locus_tag="BSU05210" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 16390439" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_388402.1" /db_xref="EnsemblGenomes-Gn:BSU05210" /db_xref="EnsemblGenomes-Tr:CAB12328" /db_xref="InterPro:IPR014922" /db_xref="InterPro:IPR016786" /db_xref="SubtiList:BG12136" /db_xref="UniProtKB/Swiss-Prot:P96666" /translation="MTNSRTNPKVDEFLSKAKKWKEEFEKLRTIILDCELTEDFKWMH PCYTYHNKNIVLIHGFKEYCALLFHKGVLLQDTDGILIQQTENVQAARQIRFTNVQEI NELENILKAYIHEAIEVEKAGLKVDVNKNIELNIPEELQNKFDEIPALKIAFEALTPG RQRAYTLYFSQAKQSKTRESRVEKYVQKILDGKGLKD*" gene 568345..568938 /gene="ydeI" /locus_tag="BSU_05210" /old_locus_tag="BSU05210" downshifts 568981 /Source="Nicolas_upshifts" /id="D248" /incds=0 /nref=2 /ntot=40 /MaxReadThrough="1.63432" /MaxDrop="2.96785" /score="2.93671425" /energy="-6.9" /TU="NA" /idTUdmin="U401" /TUdmin=0 /isTUend="TRUE" downshifts complement(569057) /Source="Nicolas_upshifts" /id="D249" /incds=0 /nref=1 /ntot=64 /MaxReadThrough="2.19009" /MaxDrop="2.9369" /score="-1.28013562" /energy="-6.9" /TU="NA" /idTUdmin="U403" /TUdmin=0 /isTUend="TRUE" promotor_-35 569070..569077 /Source="Nicolas_upshift_promotors" /id="U402" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.707292707292707" /psig="0.996003996003996" /xcortree=378 /SigmaFactorBS="tcttaggacaacattcacttactgctgaaatgcttctaaCAT TGTATgccactagacagcgTTATAAAATATTAATGCAACacctagaaatctatccaat g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 569091 /Source="Nicolas_upshifts" /id="U402" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.707292707292707" /psig="0.996003996003996" /xcortree=378 /SigmaFactorBS="tcttaggacaacattcacttactgctgaaatgcttctaaCAT TGTATgccactagacagcgTTATAAAATATTAATGCAACacctagaaatctatccaat g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 569092..569111 /Source="Nicolas_upshift_promotors" /id="U402" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.707292707292707" /psig="0.996003996003996" /xcortree=378 /SigmaFactorBS="tcttaggacaacattcacttactgctgaaatgcttctaaCAT TGTATgccactagacagcgTTATAAAATATTAATGCAACacctagaaatctatccaat g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" CDS complement(569290..569949) /gene="ydeJ" /locus_tag="BSU_05220" /old_locus_tag="BSU05220" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type lp: lipoprotein" /codon_start=1 /transl_table=11 /product="putative lipoprotein" /protein_id="NP_388403.1" /db_xref="EnsemblGenomes-Gn:BSU05220" /db_xref="EnsemblGenomes-Tr:CAB12329" /db_xref="GOA:P96667" /db_xref="SubtiList:BG12137" /db_xref="UniProtKB/Swiss-Prot:P96667" /translation="MKKRRKICYCNTALLLMILLAGCTDSKDGEAQQPSNQASAVQTD EKHTEPEESTKIRKDEAEPITESEESATKAANDTSSAEEKSKEDNVLAAYSSEKIEYA RVWLQLGPNQEIDELNVRHIAAGEPINPNDDTSASYPENVTQLAGSRLVDGSVTYHGN GDGTIHVYNVPLRWDSADDIEKGVMREVTESIIKNRKTVYVDTGDDEKIKRLIDIMMI H*" gene complement(569290..569949) /gene="ydeJ" /locus_tag="BSU_05220" /old_locus_tag="BSU05220" promotor_-10 complement(569998..570017) /Source="Nicolas_upshift_promotors" /id="U403" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.987012987012987" /psig="0.997002997002997" /xcortree=3174 /SigmaFactorBS="agatcgtttcctcttcttaaacagttttcaaTATCATcctat ctattcCATGGTAATATTTAGATACAtaaacttatatatgaagctgacctgaattaat a" /listShort="ydeJ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(570005) /Source="Nicolas_upshifts" /id="U403" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.987012987012987" /psig="0.997002997002997" /xcortree=3174 /SigmaFactorBS="agatcgtttcctcttcttaaacagttttcaaTATCATcctat ctattcCATGGTAATATTTAGATACAtaaacttatatatgaagctgacctgaattaat a" /listShort="ydeJ" /GFF_Attribute="listLong" promotor_-35 complement(570029..570034) /Source="Nicolas_upshift_promotors" /id="U403" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.987012987012987" /psig="0.997002997002997" /xcortree=3174 /SigmaFactorBS="agatcgtttcctcttcttaaacagttttcaaTATCATcctat ctattcCATGGTAATATTTAGATACAtaaacttatatatgaagctgacctgaattaat a" /listShort="ydeJ" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(570371..571234) /gene="ydeK" /locus_tag="BSU_05230" /old_locus_tag="BSU05230" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative permease" /protein_id="NP_388404.1" /db_xref="EnsemblGenomes-Gn:BSU05230" /db_xref="EnsemblGenomes-Tr:CAB12330" /db_xref="GOA:P96668" /db_xref="InterPro:IPR000620" /db_xref="SubtiList:BG12138" /db_xref="UniProtKB/Swiss-Prot:P96668" /translation="MNKTTNGWINGFIGVLIFSGSLPATRLAVSDFDPLFLTVCRAAI AGVLAGGLLLIFRQQHPAKRDLISLLVVAFGVVIGFPLLTALALQHVTSAHAIVFIGL LPLATAVFGVLRGGERPRPVFWIFSAAGSLLVAGFALIQGGGSSPLGDAYMLASIVVC GLGYAEGAKLSRRLGNWQVISWALVLSLPLMLPLSFFFTPDSWSAIGVPALLSLAYVS LFSMLIGFVFWYRGLAQGGIAAVGQLQLLQPFFGLLLASVILHEKVGWALVAVNIAVI MCVAAARRFAK*" gene complement(570371..571234) /gene="ydeK" /locus_tag="BSU_05230" /old_locus_tag="BSU05230" promotor_-35 571277..571283 /Source="Nicolas_upshift_promotors" /id="U404" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.548451548451548" /psig="0.97002997002997" /xcortree=639 /SigmaFactorBS="ctttcttgttcattgtctgtatttTCTTAACaaaaccagcag ctaAGGATTACAATGACTATAAActggaattggccttttataaacagccagttttcat a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 571298..571317 /Source="Nicolas_upshift_promotors" /id="U404" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.548451548451548" /psig="0.97002997002997" /xcortree=639 /SigmaFactorBS="ctttcttgttcattgtctgtatttTCTTAACaaaaccagcag ctaAGGATTACAATGACTATAAActggaattggccttttataaacagccagttttcat a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-10 complement(571299..571318) /Source="Nicolas_upshift_promotors" /id="U405" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.811188811188811" /psig="0.997002997002997" /xcortree=412 /SigmaFactorBS="cgttgttctcctaactggtatgcatttttttatgaaaactgg cTGTTTATAaaaggccaattccaGTTTATAGTCATTGTAATCCttagctgctggtttt g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 571313 /Source="Nicolas_upshifts" /id="U404" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.548451548451548" /psig="0.97002997002997" /xcortree=639 /SigmaFactorBS="ctttcttgttcattgtctgtatttTCTTAACaaaaccagcag ctaAGGATTACAATGACTATAAActggaattggccttttataaacagccagttttcat a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" upshifts complement(571323) /Source="Nicolas_upshifts" /id="U405" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.811188811188811" /psig="0.997002997002997" /xcortree=412 /SigmaFactorBS="cgttgttctcctaactggtatgcatttttttatgaaaactgg cTGTTTATAaaaggccaattccaGTTTATAGTCATTGTAATCCttagctgctggtttt g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(571333..571340) /Source="Nicolas_upshift_promotors" /id="U405" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.811188811188811" /psig="0.997002997002997" /xcortree=412 /SigmaFactorBS="cgttgttctcctaactggtatgcatttttttatgaaaactgg cTGTTTATAaaaggccaattccaGTTTATAGTCATTGTAATCCttagctgctggtttt g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" CDS 571389..572780 /gene="ydeL" /locus_tag="BSU_05240" /old_locus_tag="BSU05240" /function="16.3: Control" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15223311, 28348215; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative PLP-dependent transcriptional regulator" /protein_id="NP_388405.1" /db_xref="EnsemblGenomes-Gn:BSU05240" /db_xref="EnsemblGenomes-Tr:CAB12331" /db_xref="GOA:P96669" /db_xref="InterPro:IPR000524" /db_xref="InterPro:IPR004839" /db_xref="InterPro:IPR015421" /db_xref="InterPro:IPR015422" /db_xref="InterPro:IPR015424" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG12139" /db_xref="UniProtKB/Swiss-Prot:P96669" /translation="MDITPFLNRTLDIPLYQQLYRYFKENMHRGRIQKGMKLPSKRLL ANQLSISQTTVERAYEQLAAEGYIVSKPRSGWFADYHDSDFAYDRMPSTTPIQQEAEE NKQWIDFHYGNVDSSYFPFSAWRKSMVNSLDQYGHELYRPGHVLGEFELRTLIAEYLY QSRGVHCGPEQVIIGAGNPILLQILCQVFEPNISIGYEDPGYPRARKIFEANRMNIVP IPVDDEGICIQKIKEQQPNLVYVTPSHQFTLGTIMTINRRIQLLKWAAENQSFIIEDD YDGEFRYTGQPVPSLQGLDQHNRVIYMGTFSKSLLPSLRISYMILPSPLLKKGHEITS LYKQTVSCHSQLTLAEFIKNGEWQKHINRMRKLYRKKRAIVLEAVQRELGEHVRIRGE NSGLRILLDVYLPFGEKELIEKAKKHGVKIYPVSLSYQHHPPTKTVSLGFAGVSESDI REGIKKLKAAWKI*" gene 571389..572780 /gene="ydeL" /locus_tag="BSU_05240" /old_locus_tag="BSU05240" promotor_-35 572908..572915 /Source="Nicolas_upshift_promotors" /id="U406" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.984015984015984" /psig="0.999000999001" /xcortree=2260 /SigmaFactorBS="gatacgtctgtttagcgaaaaacagaatTTTTTATTtgctcc tcacAGTGCTAAAATAAACAAAATagacaattgaaaaaatagaggtgtaagaatgaag t" /listShort="ydeM, S183" /listLong="ydeO" /label="promotor_-35" promotor_-10 572926..572945 /Source="Nicolas_upshift_promotors" /id="U406" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.984015984015984" /psig="0.999000999001" /xcortree=2260 /SigmaFactorBS="gatacgtctgtttagcgaaaaacagaatTTTTTATTtgctcc tcacAGTGCTAAAATAAACAAAATagacaattgaaaaaatagaggtgtaagaatgaag t" /listShort="ydeM, S183" /listLong="ydeO" /label="promotor_-10" upshifts 572940 /Source="Nicolas_upshifts" /id="U406" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.984015984015984" /psig="0.999000999001" /xcortree=2260 /SigmaFactorBS="gatacgtctgtttagcgaaaaacagaatTTTTTATTtgctcc tcacAGTGCTAAAATAAACAAAATagacaattgaaaaaatagaggtgtaagaatgaag t" /listShort="ydeM, S183" /listLong="ydeO" CDS 572974..573399 /gene="ydeM" /locus_tag="BSU_05250" /old_locus_tag="BSU05250" /function="16.11: Scavenge (Catabolism)" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 1556068, 26349822; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative dehydratase" /protein_id="NP_388406.1" /db_xref="EnsemblGenomes-Gn:BSU05250" /db_xref="EnsemblGenomes-Tr:CAB12332" /db_xref="InterPro:IPR002539" /db_xref="InterPro:IPR029069" /db_xref="SubtiList:BG12140" /db_xref="UniProtKB/Swiss-Prot:P96670" /translation="MKLDEFTIGQVFKTKSLKVSKDDIMRFAGEFDPQYMHVDEEKAS KGRFNGIIASGIQTLAISFKLWIEEGFYGDDIIAGTEMNHMTFIKPVYPDDELFTIVE VLDKQPKRNELGILTVLLSTYNQKEVKVFEGELSVLIKR*" gene 572974..573399 /gene="ydeM" /locus_tag="BSU_05250" /old_locus_tag="BSU05250" S_feature 573400..574654 /Source="Nicolas_S_feature" /locus_tag="new_573400_574654" /HighExp="G135, H2O2, G150, HiOs, G180, Cold, Paraq, UNK1, MG 15, LBGexp" /AntisenseName="ydeN" /AntisenseCor="0.40423774227585801" /AntisenseRegPval="-11.3" /CDS_PredictionProba="0.127641" /TUshortSig="SigA" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S183" CDS complement(573452..574024) /gene="ydeN" /locus_tag="BSU_05260" /old_locus_tag="BSU05260" /EC_number="3.-.-.-" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15159570; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative alpha/beta hydrolase" /protein_id="NP_388407.1" /db_xref="EnsemblGenomes-Gn:BSU05260" /db_xref="EnsemblGenomes-Tr:CAB12333" /db_xref="GOA:P96671" /db_xref="InterPro:IPR010662" /db_xref="InterPro:IPR029058" /db_xref="PDB:1UXO" /db_xref="SubtiList:BG12141" /db_xref="UniProtKB/Swiss-Prot:P96671" /translation="MTKQVYIIHGYRASSTNHWFPWLKKRLLADGVQADILNMPNPLQ PRLEDWLDTLSLYQHTLHENTYLVAHSLGCPAILRFLEHLQLRKQLGGIILVSGFAKS LPTLQMLDEFTQGSFDHQKIIESAKHRAVIASKDDQIVPFSFSKDLAQQIDAALYEVQ HGGHFLEDEGFTSLPIVYDVLTSYFSKETR*" gene complement(573452..574024) /gene="ydeN" /locus_tag="BSU_05260" /old_locus_tag="BSU05260" downshifts complement(573457) /Source="Nicolas_upshifts" /id="D250" /incds=0 /nref=16 /ntot=160 /MaxReadThrough="1.96868" /MaxDrop="3.80195" /score="2.50673989" /energy="-11.3" /TU="NA" /idTUdmin="U407" /TUdmin=0 /isTUend="TRUE" S_feature complement(574025..574105) /Source="Nicolas_S_feature" /locus_tag="new_574025_574105_c" /HighExp="dia15, dia5, Diami, Etha, LPhT, Lbtran, Heat, H2O2, Sw, T4.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.955" /TUlongSig="NA" /TUlongPSig="NA" /label="S184" CDS complement(574106..574435) /gene="ydzF" /locus_tag="BSU_05270" /old_locus_tag="BSU05270" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative transcriptional regulator" /protein_id="NP_388408.1" /db_xref="EnsemblGenomes-Gn:BSU05270" /db_xref="EnsemblGenomes-Tr:CAB12334" /db_xref="GOA:O31494" /db_xref="InterPro:IPR002577" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG12809" /db_xref="UniProtKB/Swiss-Prot:O31494" /translation="MNSLCRSKQAPFEYTLSLIGGKWKMRILYELGCEKTMRYGELKR AMPFITHKMLSAQLKELQTDGLIHRSEVSHTPLKVEYSLSDRGRSLYPLIDEMCKWGM AQGGPHM*" gene complement(574106..574435) /gene="ydzF" /locus_tag="BSU_05270" /old_locus_tag="BSU05270" misc_feature complement(574452..574471) /Source="Nicolas_upshift_promotors" /id="U407" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.416583416583417" /psig="0.955044955044955" /xcortree=1959 /SigmaFactorBS="cctttcacttcagatcgtgaatcgccctcaaacttcaacacc gaaaatcctaatttatTCTGATATGATACTTAAAAAaggaggtttgattacaatgaat a" /listShort="ydzF, S184, ydeN" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(574469) /Source="Nicolas_upshifts" /id="U407" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.416583416583417" /psig="0.955044955044955" /xcortree=1959 /SigmaFactorBS="cctttcacttcagatcgtgaatcgccctcaaacttcaacacc gaaaatcctaatttatTCTGATATGATACTTAAAAAaggaggtttgattacaatgaat a" /listShort="ydzF, S184, ydeN" /GFF_Attribute="listLong" misc_feature 574643..574662 /Source="Nicolas_upshift_promotors" /id="U408" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.78021978021978" /psig=1 /xcortree=2345 /SigmaFactorBS="agttactttatttaaaaaaacgcatgtttttagctgaaaata tctatTATGGTATATTTAAATATAAagaaatatttgagaaatgaggaatggtatgaat a" /listShort="ydeO" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 574656 /Source="Nicolas_upshifts" /id="U408" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.78021978021978" /psig=1 /xcortree=2345 /SigmaFactorBS="agttactttatttaaaaaaacgcatgtttttagctgaaaata tctatTATGGTATATTTAAATATAAagaaatatttgagaaatgaggaatggtatgaat a" /listShort="ydeO" /GFF_Attribute="listLong" CDS 574690..575562 /gene="ydeO" /locus_tag="BSU_05280" /old_locus_tag="BSU05280" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative integral inner membrane protein" /protein_id="NP_388409.1" /db_xref="EnsemblGenomes-Gn:BSU05280" /db_xref="EnsemblGenomes-Tr:CAB12335" /db_xref="GOA:P96672" /db_xref="InterPro:IPR003740" /db_xref="InterPro:IPR019264" /db_xref="SubtiList:BG12142" /db_xref="UniProtKB/Swiss-Prot:P96672" /translation="MNTPKKHKKFKAKMILQIIMVIIGGIIAAYGLETVLIPNSVSDG GVTGLSIVGSQLFNLPLGILIAVINIPFVWLGYKQIGKSFALLSIIGIVSLAAGTSFF HHTPAIIEGDTLLITVVGGIILGFGMGLALRNGGALDGIDMLAVLLSRKLPFGTSDLI LFLNLFVFIFVSTVFGLQGALLSVIAYYIASKVIHVVEEGLSGSKTFQIITTQPELMV ETIRDQLGRSATYKEAYGGFSHEKFKEITCVINRLEETKLKEIINDIDKTAFVTVYDV AEVKGSNFRNLNHH*" gene 574690..575562 /gene="ydeO" /locus_tag="BSU_05280" /old_locus_tag="BSU05280" downshifts 575449 /Source="Nicolas_upshifts" /id="D251" /incds=1 /nref=7 /ntot=181 /MaxReadThrough="3.84278" /MaxDrop="2.68681" /score="15.0132064" /energy="-12.2" /TU="U408" /idTUdmin="U408" /TUdmin="-198" /isTUend="FALSE" downshifts 575647 /Source="Nicolas_upshifts" /id="D252" /incds=0 /nref=54 /ntot=208 /MaxReadThrough="1.19842" /MaxDrop="3.77294" /score="15.0132064" /energy="-12.2" /TU="NA" /idTUdmin="U408" /TUdmin=0 /isTUend="TRUE" CDS complement(575712..576098) /gene="ydeP" /locus_tag="BSU_05290" /old_locus_tag="BSU05290" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative transcriptional regulator" /protein_id="NP_388410.1" /db_xref="EnsemblGenomes-Gn:BSU05290" /db_xref="EnsemblGenomes-Tr:CAB12336" /db_xref="GOA:P96673" /db_xref="InterPro:IPR002577" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG12143" /db_xref="UniProtKB/Swiss-Prot:P96673" /translation="MRNRKLGIDYSSDDFEGCPVETTLDIIGGKWKGILLYHLIDGKK RFNEFRKLYPKITQRMLTLQLRELERDGVIHREVYKQVPPKVEYSLTEFGRTLEPVIL HMKDWGEKYKDRIDKLEAARKAEDKI*" gene complement(575712..576098) /gene="ydeP" /locus_tag="BSU_05290" /old_locus_tag="BSU05290" downshifts complement(575724) /Source="Nicolas_upshifts" /id="D253" /incds=0 /nref=29 /ntot=191 /MaxReadThrough="0.85093" /MaxDrop="4.4837" /score="-9.3516261" /energy="-12.9" /TU="NA" /idTUdmin="U409" /TUdmin="-1" /isTUend="TRUE" S_feature complement(576099..576163) /Source="Nicolas_S_feature" /locus_tag="new_576099_576163_c" /HighExp="Diami, dia5, Salt, dia15, Etha, Heat, G180, HiOs, LBGexp, HiTm" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S185" promotor_-35 576151..576158 /Source="Nicolas_upshift_promotors" /id="U410" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.67032967032967" /psig="0.936063936063936" /xcortree=1790 /SigmaFactorBS="agtatactttttgatactatatacattcaatgtgcgTACTTT TTatattttaatataCATCATATAATGATGTCACAtctaaggaatgaaaggaatggat c" /listShort="ydeQ" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(576152..576171) /Source="Nicolas_upshift_promotors" /id="U409" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.568431568431568" /psig="0.999000999001" /xcortree=1896 /SigmaFactorBS="gttttcatatgatccattcctttcattccttaGATGTGACat cattatatgatgTATATTAAAATATAAAAAGTacgcacattgaatgtatatagtatca a" /listShort="S185, ydeP" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(576165) /Source="Nicolas_upshifts" /id="U409" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.568431568431568" /psig="0.999000999001" /xcortree=1896 /SigmaFactorBS="gttttcatatgatccattcctttcattccttaGATGTGACat cattatatgatgTATATTAAAATATAAAAAGTacgcacattgaatgtatatagtatca a" /listShort="S185, ydeP" /GFF_Attribute="listLong" promotor_-10 576172..576191 /Source="Nicolas_upshift_promotors" /id="U410" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.67032967032967" /psig="0.936063936063936" /xcortree=1790 /SigmaFactorBS="agtatactttttgatactatatacattcaatgtgcgTACTTT TTatattttaatataCATCATATAATGATGTCACAtctaaggaatgaaaggaatggat c" /listShort="ydeQ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 576175 /Source="Nicolas_upshifts" /id="U410" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.67032967032967" /psig="0.936063936063936" /xcortree=1790 /SigmaFactorBS="agtatactttttgatactatatacattcaatgtgcgTACTTT TTatattttaatataCATCATATAATGATGTCACAtctaaggaatgaaaggaatggat c" /listShort="ydeQ" /GFF_Attribute="listLong" promotor_-35 complement(576186..576193) /Source="Nicolas_upshift_promotors" /id="U409" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.568431568431568" /psig="0.999000999001" /xcortree=1896 /SigmaFactorBS="gttttcatatgatccattcctttcattccttaGATGTGACat cattatatgatgTATATTAAAATATAAAAAGTacgcacattgaatgtatatagtatca a" /listShort="S185, ydeP" /GFF_Attribute="listLong" /label="promotor_-35" CDS 576209..576802 /gene="ydeQ" /locus_tag="BSU_05300" /old_locus_tag="BSU05300" /EC_number="1.6.99.-" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative NAD(P)H oxidoreductase involved in regulating potassium efflux" /protein_id="NP_388411.1" /db_xref="EnsemblGenomes-Gn:BSU05300" /db_xref="EnsemblGenomes-Tr:CAB12337" /db_xref="GOA:P96674" /db_xref="InterPro:IPR003680" /db_xref="InterPro:IPR029039" /db_xref="SubtiList:BG12144" /db_xref="UniProtKB/Swiss-Prot:P96674" /translation="MDHMKTLVLVVHPNIESSRINKKWKEAVLSEPDVTVHDLYEKYR DQPIDVEFEQQQLLAHDRIVFQFPLYWYSSPPLLKQWFDEVFTFGWAHGPGGNKLKGK EWVTAMSIGSPEHSYQAGGYNLFSISELTKPFQASAHLVGMTYLPSFAEYRANTISDQ EIAESANRYVKHITNIELNPKVRLQRYLKQLESVDLT*" gene 576209..576802 /gene="ydeQ" /locus_tag="BSU_05300" /old_locus_tag="BSU05300" CDS complement(576946..578133) /gene="ydeR" /locus_tag="BSU_05310" /old_locus_tag="BSU05310" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative efflux transporter" /protein_id="NP_388412.1" /db_xref="EnsemblGenomes-Gn:BSU05310" /db_xref="EnsemblGenomes-Tr:CAB12338" /db_xref="GOA:P96675" /db_xref="InterPro:IPR011701" /db_xref="InterPro:IPR020846" /db_xref="InterPro:IPR036259" /db_xref="SubtiList:BG12145" /db_xref="UniProtKB/Swiss-Prot:P96675" /translation="MANGNKQAGQRISPSLTLLLATACGIIVANLYYAQPLVGLISKA IGLSPSGAGLIVTLTQIGYVAGLLFLVPLGDIIENKKLIVVSLLLSAAALTLTAFVKH GTLFLAAAFFVGLGSIAAQVLVPFASYLASDAARGRVVGNVMSGLLLGIMLSRPISSL VADIWGWNAIFALSAVVSVILAIVLSKVLPARKPTANTNYTALLGSMWKLLRTTPVLR RRAIYHAFVFGAFSLFWTTVPLLLSGPDFHFSQKAIALYALVGIAGAVTAPIGGRLAD RGLTRLATGIALGVVVVSLLLPLMIQSSSPVGITVLVAAAILLDMGVSANLVLSQRAI FSLAPEIRSRLNGLFMAIFFLGGAIGSSIGGWAYASGGWSTALWIGIAFPVIALLYFI TEK*" gene complement(576946..578133) /gene="ydeR" /locus_tag="BSU_05310" /old_locus_tag="BSU05310" promotor_-35 578269..578273 /Source="Nicolas_upshift_promotors" /id="U411" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.605394605394605" /psig="0.999000999001" /xcortree=2381 /SigmaFactorBS="aaaaataatatactaaacgttcagttttgtaaatggatttct GTTTTctttttttattcaaTTTAAGTATACTGAACGTATagtttatattgcgggaagg a" /listShort="ydeS, ydzO" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 578287 /Source="Nicolas_upshifts" /id="U411" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.605394605394605" /psig="0.999000999001" /xcortree=2381 /SigmaFactorBS="aaaaataatatactaaacgttcagttttgtaaatggatttct GTTTTctttttttattcaaTTTAAGTATACTGAACGTATagtttatattgcgggaagg a" /listShort="ydeS, ydzO" /GFF_Attribute="listLong" promotor_-10 578288..578307 /Source="Nicolas_upshift_promotors" /id="U411" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.605394605394605" /psig="0.999000999001" /xcortree=2381 /SigmaFactorBS="aaaaataatatactaaacgttcagttttgtaaatggatttct GTTTTctttttttattcaaTTTAAGTATACTGAACGTATagtttatattgcgggaagg a" /listShort="ydeS, ydzO" /GFF_Attribute="listLong" /label="promotor_-10" CDS 578337..578933 /gene="ydeS" /locus_tag="BSU_05320" /old_locus_tag="BSU05320" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15944459; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative transcriptional regulator (TetR/AcrR family)" /protein_id="NP_388413.1" /db_xref="EnsemblGenomes-Gn:BSU05320" /db_xref="EnsemblGenomes-Tr:CAB12339" /db_xref="GOA:P96676" /db_xref="InterPro:IPR001647" /db_xref="InterPro:IPR009057" /db_xref="InterPro:IPR011075" /db_xref="InterPro:IPR036271" /db_xref="SubtiList:BG12146" /db_xref="UniProtKB/Swiss-Prot:P96676" /translation="MQSKRGRPRDEGTHKAILSAAYDLLLEKGFDAVTVDKIAERAKV SKATIYKWWSNKAAVIMDSFLSTATDRLPVPDTGSSVQDIVTHATNLARFLTSREGTV IKELIGAGQLDEKLAEEYRTRFFQPRRLQAKGLLEKGIQKGELRENLDIEVSIDLIYG PIFYRLLITGDEVNDSYVRDLVMNAFKGVQATSATESM*" gene 578337..578933 /gene="ydeS" /locus_tag="BSU_05320" /old_locus_tag="BSU05320" CDS 579047..579232 /gene="ydzO" /locus_tag="BSU_05329" /old_locus_tag="BSU05329" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_003097684.1" /db_xref="EnsemblGenomes-Gn:BSU05329" /db_xref="EnsemblGenomes-Tr:CAX52555" /db_xref="UniProtKB/Swiss-Prot:C0H3V9" /translation="MSKKKSFNREYITSYYYIPFHRLEQGFYTSMEYRKVGVFKQQGK IDGHYVGVMAMEKILAM*" gene 579047..579232 /gene="ydzO" /locus_tag="BSU_05329" /old_locus_tag="BSU05329" downshifts 579211 /Source="Nicolas_upshifts" /id="D254" /incds=0 /nref=5 /ntot=123 /MaxReadThrough="1.06987" /MaxDrop="2.89833" /score="-5.04743481" /energy="-6.3" /TU="NA" /idTUdmin="U411" /TUdmin=0 /isTUend="TRUE" promotor_-35 579344..579347 /Source="Nicolas_upshift_promotors" /id="U412" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.356643356643357" /psig="0.99000999000999" /xcortree=2480 /SigmaFactorBS="tctatgaccactcccataactgaaatagtctaatatttatac cagaagggATTGtttatataaataaaAGTTTATATAATGACGGGGGcgctaaggaaac g" /listShort="S186, aseR, ydfA, ydzS, ydzS" /GFF_Attribute="listLong" /label="promotor_-35" S_feature 579354..579540 /Source="Nicolas_S_feature" /locus_tag="new_579354_579540" /HighExp="LBGstat, G180, LBGexp, G135, Paraq, G150, Oxctl, dia0, Diami, H2O2" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.99" /TUlongSig="NA" /TUlongPSig="NA" /label="S186" upshifts 579354 /Source="Nicolas_upshifts" /id="U412" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.356643356643357" /psig="0.99000999000999" /xcortree=2480 /SigmaFactorBS="tctatgaccactcccataactgaaatagtctaatatttatac cagaagggATTGtttatataaataaaAGTTTATATAATGACGGGGGcgctaaggaaac g" /listShort="S186, aseR, ydfA, ydzS, ydzS" /GFF_Attribute="listLong" promotor_-10 579362..579381 /Source="Nicolas_upshift_promotors" /id="U412" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.356643356643357" /psig="0.99000999000999" /xcortree=2480 /SigmaFactorBS="tctatgaccactcccataactgaaatagtctaatatttatac cagaagggATTGtttatataaataaaAGTTTATATAATGACGGGGGcgctaaggaaac g" /listShort="S186, aseR, ydfA, ydzS, ydzS" /GFF_Attribute="listLong" /label="promotor_-10" CDS 579541..579876 /gene="aseR" /locus_tag="BSU_05330" /old_locus_tag="BSU05330" /function="16.3: Control" /function="16.12: Sense" /experiment="publication(s) with functional evidences, PMID:15948947, 16430705" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15948947, 16430705; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator (metals sensing ArsR-SmtB repressors family)" /protein_id="NP_388414.1" /db_xref="EnsemblGenomes-Gn:BSU05330" /db_xref="EnsemblGenomes-Tr:CAB12340" /db_xref="GOA:P96677" /db_xref="InterPro:IPR001845" /db_xref="InterPro:IPR011991" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG12147" /db_xref="UniProtKB/Swiss-Prot:P96677" /translation="MTIDVAAMTRCLKTLSDQTRLIMMRLFLEQEYCVCQLVDMFEMS QPAISQHLRKLKNAGFVNEDRRGQWRYYSINGSCPEFDTLQLILHQIDQEDELLNHIK QKKTQACCQ*" gene 579541..579876 /gene="aseR" /locus_tag="BSU_05330" /old_locus_tag="BSU05330" CDS 579889..581196 /gene="arsF" /locus_tag="BSU_05340" /old_locus_tag="BSU05340" /function="16.1: Circulate" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 12950922, 14970228, 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="arsenite/antimonite/H+ antiporter" /protein_id="NP_388415.1" /db_xref="EnsemblGenomes-Gn:BSU05340" /db_xref="EnsemblGenomes-Tr:CAB12341" /db_xref="GOA:P96678" /db_xref="InterPro:IPR000802" /db_xref="SubtiList:BG12148" /db_xref="UniProtKB/Swiss-Prot:P96678" /translation="MTSMILAVFIFLLTLVLVIWQPKNLSIGWSACGGAVLALIAGVV NFHDVLTVTGIVWNATLAFVAIILISLILDNIGFFEWAALHMAKAAKGYGVRMFVYVS LLGAIVAALFANDGAALILTPIVLAMVRALHFNEKLVFPFIIASGFIADTTSLPFVVS NLVNIVSADYFHITFIDYASRMVVPYLFSLLASIIVLYLFFRKSIPKRYDLTEVKKPV EAIKDQNMFRLSWYILGLLLIGYFASEFFSIPVSVVAGSIAIIFLIAAQKSPAVHTKK VVKEAPWAIVFFSIGMYVVVYGVRNAGLTDVLSDVIQAAADQGLFAGTIGMGFIAAIL SSIMNNLPTVMIDALAIAGTDTHGMMREALIYANVIGSDLGPKITPIGSLATLLWLHV LSHKGMKISWGTYFKTGIILTIPTLLITLVGLYIWLLIIHSCF*" gene 579889..581196 /gene="arsF" /locus_tag="BSU_05340" /old_locus_tag="BSU05340" CDS 581228..581332 /gene="ydzSn" /locus_tag="BSU_05343" /old_locus_tag="BSU05343" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /pseudo /codon_start=1 /transl_table=11 /product="conserved hypothetical protein; N-terminal part of ydzS" /translation="CTGNSCRSQMAEGWGRKYLGAKWNVYSAGIEAQG*" gene 581228..581332 /gene="ydzSn" /locus_tag="BSU_05343" /old_locus_tag="BSU05343" /pseudo CDS 581341..581454 /gene="ydzSc" /locus_tag="BSU_05344" /old_locus_tag="BSU05344" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /pseudo /codon_start=1 /transl_table=11 /product="conserved hypothetical protein; C-terminal part of ydzS" /translation="AVKAMKEAGIDISNQTSEKFDDPAKAHGTEEVFPKGP*" gene 581341..581454 /gene="ydzSc" /locus_tag="BSU_05344" /old_locus_tag="BSU05344" /pseudo promotor_-35 581640..581648 /Source="Nicolas_upshift_promotors" /id="U413" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.987012987012987" /psig="0.987012987012987" /xcortree=429 /SigmaFactorBS="cagggaagttatttagctggtgacAGAGGAAAAttgatttgt gAACAGAATCATGAAGGAGAcggtgttttaaaggagttgtctgttttgcaggaattaa c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 581659..581677 /Source="Nicolas_upshift_promotors" /id="U413" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.987012987012987" /psig="0.987012987012987" /xcortree=429 /SigmaFactorBS="cagggaagttatttagctggtgacAGAGGAAAAttgatttgt gAACAGAATCATGAAGGAGAcggtgttttaaaggagttgtctgttttgcaggaattaa c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 581676 /Source="Nicolas_upshifts" /id="U413" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.987012987012987" /psig="0.987012987012987" /xcortree=429 /SigmaFactorBS="cagggaagttatttagctggtgacAGAGGAAAAttgatttgt gAACAGAATCATGAAGGAGAcggtgttttaaaggagttgtctgttttgcaggaattaa c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" CDS 581694..582479 /gene="ydfB" /locus_tag="BSU_05350" /old_locus_tag="BSU05350" /function="16.6: Maintain" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 12793527; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative acetyltransferase" /protein_id="NP_388416.1" /db_xref="EnsemblGenomes-Gn:BSU05350" /db_xref="EnsemblGenomes-Tr:CAB12342" /db_xref="GOA:P96679" /db_xref="InterPro:IPR000182" /db_xref="InterPro:IPR016181" /db_xref="InterPro:IPR027365" /db_xref="SubtiList:BG12149" /db_xref="UniProtKB/Swiss-Prot:P96679" /translation="MSVLQELTKKKYSSLKTMFDDKYCPTFVYSILDQTIPGAVYADD QTFPKSFFIGTESGIYFIAGDQGNRDFHDFIAGYYEEQVKSSKRFTLFSSSDTWDSVL KPILKDDLNQMRRAAFSYQPKSFKKTLQLPKGLVLKRIDEDIISHSTAFNSAYYEEYW NSVSQFASKGFGFAVLHGNHVVSECTSIFLGHNRAEMDIYTLEEYRGLGLAYCVANRF IAFCMENGIVPSWDCDICNNSSIALAAKLGFKTVTEYTIYYSG*" gene 581694..582479 /gene="ydfB" /locus_tag="BSU_05350" /old_locus_tag="BSU05350" downshifts 581741 /Source="Nicolas_upshifts" /id="D255" /incds=0 /nref=3 /ntot=24 /MaxReadThrough="2.67554" /MaxDrop="5.08398" /score="39.1565399" /energy="-19.2" /TU="NA" /idTUdmin="U413" /TUdmin=0 /isTUend="TRUE" downshifts 582489 /Source="Nicolas_upshifts" /id="D256" /incds=0 /nref=2 /ntot=90 /MaxReadThrough="0.161840000000001" /MaxDrop="3.51451" /score="-0.169292431" /energy="-13.6" /TU="NA" /idTUdmin="U413" /TUdmin=748 /isTUend="FALSE" CDS complement(582536..583456) /gene="ydfC" /locus_tag="BSU_05360" /old_locus_tag="BSU05360" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative aminoacid exporter" /protein_id="NP_388417.1" /db_xref="EnsemblGenomes-Gn:BSU05360" /db_xref="EnsemblGenomes-Tr:CAB12343" /db_xref="GOA:P96680" /db_xref="InterPro:IPR000620" /db_xref="SubtiList:BG12150" /db_xref="UniProtKB/Swiss-Prot:P96680" /translation="MRKKTVQIMISHSLMIGLWASAFPGIRAGLEGYTPEHLALFRLL IGSMALLLFAVLTQMRLPDLKDIPAIFLLGFLGFAFYHILLNIGEKTVSAGVASLLVT TAPIFSAMLSRLFYKEHFGFTKWLGSMISLLGVLLIAFGAGDFTYSMSGILVILLAAF SESIYFVFQARYIKKYGFIPFVTFTIWGGTIPMLVFLPGLGEEMMNASISATLSIVYL GLLPTVIPYFALAYVTSFVGASEATLSLYVTPALALIISWLWIGEIPTLLSLLGGVVT VGGVCFTYLKVNKMNKIFITHFSAKRVKKL*" gene complement(582536..583456) /gene="ydfC" /locus_tag="BSU_05360" /old_locus_tag="BSU05360" CDS 583589..585037 /gene="ydfD" /locus_tag="BSU_05370" /old_locus_tag="BSU05370" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15223311, 28348215; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative PLP-dependent transcriptional regulator" /protein_id="NP_388418.1" /db_xref="EnsemblGenomes-Gn:BSU05370" /db_xref="EnsemblGenomes-Tr:CAB12344" /db_xref="GOA:P96681" /db_xref="InterPro:IPR000524" /db_xref="InterPro:IPR004839" /db_xref="InterPro:IPR015421" /db_xref="InterPro:IPR015422" /db_xref="InterPro:IPR015424" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG12151" /db_xref="UniProtKB/Swiss-Prot:P96681" /translation="MSFPEEKKMKKLPKYRQIVHFIKEKIGNGEWPIGSKIPSQRTLA KDFQVNRSTVITALEELMADGLIEGTMGKGTVVINNTWTLMAKNSAPDWDQYVTSGIQ MPSRKIVQEINQSESNTDLIQLSKGELSAEIFPLAVMKEMMGKVSQHMEAFGYEEPKG YLPLREALSNYLKTIGINVSSSSILIVSGALQALQLISMGLLQRGSTVYLDQPSYLYS LHVFQSAGMKLTGLPMDNEGLLPENVHLTRGERGRAILYTNPCFHNPTGILMSKKRRE EILAVSENTQLPIIEDDIYRELWIDEIPPYPIKTIDKNGHVLYIGSLSKTLSPGLRIG WIVGPEPVIERLSDIKMQTDYGSSSLSQRVAAEWFTSGHYQQHVEKVRQQLKVRRELA LSALETHLKEVATWNIPKGGFFVWIKILPSISMKLLYTKALSKGILINLGSIYAQEKG NYIRLSYAYASLEDLQKGIYELGLMIKELASR*" gene 583589..585037 /gene="ydfD" /locus_tag="BSU_05370" /old_locus_tag="BSU05370" CDS complement(585155..585778) /gene="ydfE" /locus_tag="BSU_05380" /old_locus_tag="BSU05380" /function="16.8: Protect" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative flavoprotein" /protein_id="NP_388419.1" /db_xref="EnsemblGenomes-Gn:BSU05380" /db_xref="EnsemblGenomes-Tr:CAB12345" /db_xref="GOA:P96682" /db_xref="InterPro:IPR002563" /db_xref="InterPro:IPR012349" /db_xref="SubtiList:BG12152" /db_xref="UniProtKB/Swiss-Prot:P96682" /translation="MDIKKQDTRRFKEIKPKIMYYGTSTFLLTTLNEDGTTNISPMSS SWALGHYIILGVGLGGKAIDNLERHKECVINLPGPDLWENVERISSYSGKKSIPPLKK QIGFTYKKEKYEAAGLTPLQSKTVSPTRIKECPIQIEAEVKHIRLPEYESSFAIVETQ ALHFHAEESIILDENHINPSKWSPLIYNFRHYFGLGREVGKTFRSET*" gene complement(585155..585778) /gene="ydfE" /locus_tag="BSU_05380" /old_locus_tag="BSU05380" promotor_-10 complement(585802..585821) /Source="Nicolas_upshift_promotors" /id="U414" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.398601398601399" /psig="0.999000999001" /xcortree=2726 /SigmaFactorBS="atattaggattcatgattttcctccttacattcatatttCGA TGATagttgaaatgttaaTCCTTTACAATATAAATGTAagcgtgacaaggaggaaaaa a" /listShort="ydfE" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 585810..585817 /Source="Nicolas_upshift_promotors" /id="U415" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.815184815184815" /psig=1 /xcortree=2389 /SigmaFactorBS="tccaacgttttttcctccttgtcacgcttacatttaTATTGT AAaggattaacatttcAACTATCATCGAAATATGAAtgtaaggaggaaaatcatgaat c" /listShort="ydfF" /GFF_Attribute="listLong" /label="promotor_-35" upshifts complement(585821) /Source="Nicolas_upshifts" /id="U414" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.398601398601399" /psig="0.999000999001" /xcortree=2726 /SigmaFactorBS="atattaggattcatgattttcctccttacattcatatttCGA TGATagttgaaatgttaaTCCTTTACAATATAAATGTAagcgtgacaaggaggaaaaa a" /listShort="ydfE" /GFF_Attribute="listLong" promotor_-10 585832..585851 /Source="Nicolas_upshift_promotors" /id="U415" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.815184815184815" /psig=1 /xcortree=2389 /SigmaFactorBS="tccaacgttttttcctccttgtcacgcttacatttaTATTGT AAaggattaacatttcAACTATCATCGAAATATGAAtgtaaggaggaaaatcatgaat c" /listShort="ydfF" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 585834 /Source="Nicolas_upshifts" /id="U415" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.815184815184815" /psig=1 /xcortree=2389 /SigmaFactorBS="tccaacgttttttcctccttgtcacgcttacatttaTATTGT AAaggattaacatttcAACTATCATCGAAATATGAAtgtaaggaggaaaatcatgaat c" /listShort="ydfF" /GFF_Attribute="listLong" promotor_-35 complement(585836..585842) /Source="Nicolas_upshift_promotors" /id="U414" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.398601398601399" /psig="0.999000999001" /xcortree=2726 /SigmaFactorBS="atattaggattcatgattttcctccttacattcatatttCGA TGATagttgaaatgttaaTCCTTTACAATATAAATGTAagcgtgacaaggaggaaaaa a" /listShort="ydfE" /GFF_Attribute="listLong" /label="promotor_-35" CDS 585868..586548 /gene="ydfF" /locus_tag="BSU_05390" /old_locus_tag="BSU05390" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative transcriptional regulator" /protein_id="NP_388420.1" /db_xref="EnsemblGenomes-Gn:BSU05390" /db_xref="EnsemblGenomes-Tr:CAB12346" /db_xref="GOA:P96683" /db_xref="InterPro:IPR001845" /db_xref="InterPro:IPR011991" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG12153" /db_xref="UniProtKB/Swiss-Prot:P96683" /translation="MNPNIAKISSLLSDPSRSSILLSLMDGRIHPAGELAYLANIKPQ TASFHLNKLLEAKLISVEKHGRHRYYRLADSDAANVIEQLLHIAPKAKVKSLKESKEK KDLHFARTCYDHLAGYVGVQMAHSLVEQGMLKKVDLNFEVTSEGALFFSKLGINEEQQ RNKRRAFARCCLDWSERQHHIAGALGNALLVRMLEEEWIVRMPKTRAIRITQSGKIAF EKHLNVKI*" gene 585868..586548 /gene="ydfF" /locus_tag="BSU_05390" /old_locus_tag="BSU05390" downshifts 586581 /Source="Nicolas_upshifts" /id="D257" /incds=0 /nref=113 /ntot=245 /MaxReadThrough="0.50202" /MaxDrop="4.24716" /score="-7.74889591" /energy="-4.5" /TU="U415" /idTUdmin="U415" /TUdmin="-22" /isTUend="TRUE" CDS complement(586628..587071) /gene="ydfG" /locus_tag="BSU_05400" /old_locus_tag="BSU05400" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_388421.1" /db_xref="EnsemblGenomes-Gn:BSU05400" /db_xref="EnsemblGenomes-Tr:CAB12347" /db_xref="GOA:P96684" /db_xref="InterPro:IPR003779" /db_xref="InterPro:IPR004675" /db_xref="InterPro:IPR029032" /db_xref="SubtiList:BG12154" /db_xref="UniProtKB/Swiss-Prot:P96684" /translation="MSQRVSYYEIAPEGMKIMMDMEKYTKQSSINRTTRELIKIRVSQ MNGCAFCIDMHTSDARKMGETEQRIYCLHAWNECDFYSPEEKAALELSEHITLIPSKR VPDELYHRVREHYDEEQYVDLVLIINQINSWNRISIAMGNRAASK*" gene complement(586628..587071) /gene="ydfG" /locus_tag="BSU_05400" /old_locus_tag="BSU05400" downshifts complement(586633) /Source="Nicolas_upshifts" /id="D258" /incds=0 /nref=10 /ntot=187 /MaxReadThrough="1.76648" /MaxDrop="3.73786" /score="0.225628164" /energy="-10.8" /TU="NA" /idTUdmin="U416" /TUdmin=2 /isTUend="TRUE" promotor_-10 complement(587094..587113) /Source="Nicolas_upshift_promotors" /id="U416" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.96903096903097" /psig=1 /xcortree=2022 /SigmaFactorBS="gcttctttccaaaagacgctgaaacagctgtcattcaaaccg caCATTGGTAaaatgatcaatacCGGGATACAATCTAGGTATTctatggaaaggagtc t" /listShort="ydfG" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(587118) /Source="Nicolas_upshifts" /id="U416" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.96903096903097" /psig=1 /xcortree=2022 /SigmaFactorBS="gcttctttccaaaagacgctgaaacagctgtcattcaaaccg caCATTGGTAaaatgatcaatacCGGGATACAATCTAGGTATTctatggaaaggagtc t" /listShort="ydfG" /GFF_Attribute="listLong" promotor_-35 complement(587127..587134) /Source="Nicolas_upshift_promotors" /id="U416" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.96903096903097" /psig=1 /xcortree=2022 /SigmaFactorBS="gcttctttccaaaagacgctgaaacagctgtcattcaaaccg caCATTGGTAaaatgatcaatacCGGGATACAATCTAGGTATTctatggaaaggagtc t" /listShort="ydfG" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(587157..587336) /gene="ydzP" /locus_tag="BSU_05408" /old_locus_tag="BSU05408" /function="18: Unknown function" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_003097685.1" /db_xref="EnsemblGenomes-Gn:BSU05408" /db_xref="EnsemblGenomes-Tr:CAX52558" /db_xref="GOA:C0H3W0" /db_xref="UniProtKB/Swiss-Prot:C0H3W0" /translation="MNMYWFLGALLYFLIGTYIFIRVTRDSQSGSWILLALAAPLIIA GYPYFYSKKLLSKRR*" gene complement(587157..587336) /gene="ydzP" /locus_tag="BSU_05408" /old_locus_tag="BSU05408" CDS complement(587333..587476) /gene="ydzQ" /locus_tag="BSU_05409" /old_locus_tag="BSU05409" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_003097686.1" /db_xref="EnsemblGenomes-Gn:BSU05409" /db_xref="EnsemblGenomes-Tr:CAX52559" /db_xref="UniProtKB/Swiss-Prot:C0H3W1" /translation="MKSIDLTILSLKRKGIRTEKVLKNQNPDRLSHMTDKNAQPKSKE KEE*" gene complement(587333..587476) /gene="ydzQ" /locus_tag="BSU_05409" /old_locus_tag="BSU05409" promotor_-35 587427..587429 /Source="Nicolas_upshift_promotors" /id="U417" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.649350649350649" /psig="0.998001998001998" /xcortree=2487 /SigmaFactorBS="tctgattttttaataccttttcggtcCGGattccttttctct ttAATGATAAAATTGTGAGATCaatcgatttcaatgatgatcattccttcaatgaata g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 587445..587464 /Source="Nicolas_upshift_promotors" /id="U417" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.649350649350649" /psig="0.998001998001998" /xcortree=2487 /SigmaFactorBS="tctgattttttaataccttttcggtcCGGattccttttctct ttAATGATAAAATTGTGAGATCaatcgatttcaatgatgatcattccttcaatgaata g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 587461 /Source="Nicolas_upshifts" /id="U417" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.649350649350649" /psig="0.998001998001998" /xcortree=2487 /SigmaFactorBS="tctgattttttaataccttttcggtcCGGattccttttctct ttAATGATAAAATTGTGAGATCaatcgatttcaatgatgatcattccttcaatgaata g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" CDS 587744..588967 /gene="ydfH" /locus_tag="BSU_05410" /old_locus_tag="BSU05410" /function="16.3: Control" /function="16.12: Sense" /experiment="publication(s) with functional evidences, PMID:11717295, 15941986" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11717295, 15941986; Product type rc: receptor" /codon_start=1 /transl_table=11 /product="two-component sensor histidine kinase [YdfI]" /protein_id="NP_388422.1" /db_xref="EnsemblGenomes-Gn:BSU05410" /db_xref="EnsemblGenomes-Tr:CAB12348" /db_xref="GOA:P96685" /db_xref="InterPro:IPR003594" /db_xref="InterPro:IPR011712" /db_xref="InterPro:IPR036890" /db_xref="SubtiList:BG12155" /db_xref="UniProtKB/Swiss-Prot:P96685" /translation="MLIRNPFKDKYYSHDRRALNMLALRVPGLAFILMIYIASIVLQF VSGGWSILLLYAFTILIAIFALLHWHSYRWVKKRVILYFAVQGLITFALANLMTGFFI LVIIGLYAFLIGQIIGMADRRRTFLILYLLLLLVINSAYHLHKGEVLHFIVIAAPIMI VIITYAATFFAQVDEKIKAQLTLERLELAHQQVEQLTLQNERQRMARDLHDTLAQGLV SLNMQLDAIHVHLAKGNTERAKEIIQQSMKRVKSTIADARSAIDDLRSKSEEIGVLKE RITSLMDHFIESTGMACLLDYRLHQVLDVRTAENCYYIIGECMTNAAKHAEAKTIWIS IWDDEKGRLHLTVKDNGKGFDVEKGKKKRGHYGLLGIQERVRAINGQFNIKSTKLKGT QIEITVPIQGEMQDE*" gene 587744..588967 /gene="ydfH" /locus_tag="BSU_05410" /old_locus_tag="BSU05410" CDS 588960..589601 /gene="ydfI" /locus_tag="BSU_05420" /old_locus_tag="BSU05420" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:11717295, 15941986" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11717295, 15941986; Product type r: regulator" /codon_start=1 /transl_table=11 /product="two-component response regulator [YdfH]" /protein_id="NP_388423.1" /db_xref="EnsemblGenomes-Gn:BSU05420" /db_xref="EnsemblGenomes-Tr:CAB12349" /db_xref="GOA:P96686" /db_xref="InterPro:IPR000792" /db_xref="InterPro:IPR001789" /db_xref="InterPro:IPR011006" /db_xref="InterPro:IPR016032" /db_xref="InterPro:IPR036388" /db_xref="SubtiList:BG12156" /db_xref="UniProtKB/Swiss-Prot:P96686" /translation="MNKVLIVDDHLVVREGLKLLIETNDQYTIIGEAENGKVAVRLAD ELEPDIILMDLYMPEMSGLEAIKQIKEKHDTPIIILTTYNEDHLMIEGIELGAKGYLL KDTSSETLFHTMDAAIRGNVLLQPDILKRLQEIQFERMKKQRNETQLTEKEVIVLKAI AKGLKSKAIAFDLGVSERTVKSRLTSIYNKLGANSRTEAVTIAMQKGILTIDN*" gene 588960..589601 /gene="ydfI" /locus_tag="BSU_05420" /old_locus_tag="BSU05420" downshifts 589595 /Source="Nicolas_upshifts" /id="D259" /incds=0 /nref=5 /ntot=147 /MaxReadThrough="1.15378" /MaxDrop="2.65603" /score="8.33575703" /energy="-6.4" /TU="NA" /idTUdmin="U419" /TUdmin="-176" /isTUend="FALSE" promotor_-10 complement(589628..589647) /Source="Nicolas_upshift_promotors" /id="U418" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.796203796203796" /psig="0.999000999001" /xcortree=1843 /SigmaFactorBS="tcctttcaacacattgcttgatcacattctttctcattgtaG TTGACAAtgaaatgaaaaaaACGTACATTCGGGCATGTACgtttgggcaattttcaaa t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(589649) /Source="Nicolas_upshifts" /id="U418" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.796203796203796" /psig="0.999000999001" /xcortree=1843 /SigmaFactorBS="tcctttcaacacattgcttgatcacattctttctcattgtaG TTGACAAtgaaatgaaaaaaACGTACATTCGGGCATGTACgtttgggcaattttcaaa t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(589661..589668) /Source="Nicolas_upshift_promotors" /id="U418" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.796203796203796" /psig="0.999000999001" /xcortree=1843 /SigmaFactorBS="tcctttcaacacattgcttgatcacattctttctcattgtaG TTGACAAtgaaatgaaaaaaACGTACATTCGGGCATGTACgtttgggcaattttcaaa t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 589709..589714 /Source="Nicolas_upshift_promotors" /id="U419" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.833166833166833" /psig="0.833166833166833" /xcortree=1016 /SigmaFactorBS="actacaatgagaaagaatgtgatcaagcaatgtgttgaaagg AGATTAtcatgtcaaaaatgTTATATACATTAGGAGGATgggttgctcgcaatcgcat a" /listShort="ydfJ" /GFF_Attribute="listLong" /label="promotor_-35" CDS 589717..591891 /gene="ydfJ" /locus_tag="BSU_05430" /old_locus_tag="BSU05430" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15941986; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative proton metabolite efflux transporter" /protein_id="NP_388424.1" /db_xref="EnsemblGenomes-Gn:BSU05430" /db_xref="EnsemblGenomes-Tr:CAB12350" /db_xref="GOA:P96687" /db_xref="InterPro:IPR000731" /db_xref="InterPro:IPR004869" /db_xref="SubtiList:BG12157" /db_xref="UniProtKB/Swiss-Prot:P96687" /translation="MSKMLYTLGGWVARNRIKAICAWIVVLVAAIGLAVTLKPSFSED MSIPDTPSEKAMDVIQKEFPHGPDKGSIRVIFGAGDGEKLTGKPAKKAIEDTFKEISK DDSVDSIASPFVTGTIAKDGTVAYADIQYKSSADDIKDYSIKHLKDSLKMADDEGLQT ELSGDVPGAEMEIGGVSEIVGIILAFVVLAITFGSLLIAGLPILTALIGLGVSIGLVL IGTQVFDIASVSLSLAGMIGLAVGIDYALFIFTKHRQFLGEGIQKNESIARAVGTAGS AVVFAGLTVIVALCGLTVVNIPFMSAMGLTAGLSVLMAVLASITLVPAVLSIAGKRMI PKSNKKIEKQSTETNVWGRFVTKNPIMLSVCSILILIVISIPSMHLELGLPDAGMKAK DNPDRRAYDLLAEGFGEGFNGQLTIVADATNATENKAEAFADAVKEIKGLDHVASVTP AMPNKEGNFAIITVVPETGPNDVTTKDLVHDVRSLSDKNGVDLLVTGSTAVNIDISDR LNDAIPVFAVLIVGFAFVLLTIVFRSLLVPLVAVAGFMLTMTATLGICVFVLQDGNLI DFFKIPEKGPILAFLPILSIGILFGLAMDYQVFLVSRMREEYVKTNNPVQAIQAGLKH SGPVVTAAGLIMIFVFAGFIFAGEASIKANGLALSFGVLFDAFIVRMTLIPSVMKLMG NAAWYLPKWLDKIIPNVDIEGHQLTKEIQPEIDHEQKKQISV*" gene 589717..591891 /gene="ydfJ" /locus_tag="BSU_05430" /old_locus_tag="BSU05430" upshifts 589727 /Source="Nicolas_upshifts" /id="U419" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.833166833166833" /psig="0.833166833166833" /xcortree=1016 /SigmaFactorBS="actacaatgagaaagaatgtgatcaagcaatgtgttgaaagg AGATTAtcatgtcaaaaatgTTATATACATTAGGAGGATgggttgctcgcaatcgcat a" /listShort="ydfJ" /GFF_Attribute="listLong" promotor_-10 589729..589747 /Source="Nicolas_upshift_promotors" /id="U419" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.833166833166833" /psig="0.833166833166833" /xcortree=1016 /SigmaFactorBS="actacaatgagaaagaatgtgatcaagcaatgtgttgaaagg AGATTAtcatgtcaaaaatgTTATATACATTAGGAGGATgggttgctcgcaatcgcat a" /listShort="ydfJ" /GFF_Attribute="listLong" /label="promotor_-10" misc_feature complement(590793..590811) /Source="Nicolas_upshift_promotors" /id="U420" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.763236763236763" /psig="0.763236763236763" /xcortree=1205 /SigmaFactorBS="atgcatagatgggatactaatgacgatcaaaatcagaatgct GCATACACTTAGCATGATAggatttttggtgacaaagcgtccccagacatttgtttca g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(590793) /Source="Nicolas_upshifts" /id="U420" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.763236763236763" /psig="0.763236763236763" /xcortree=1205 /SigmaFactorBS="atgcatagatgggatactaatgacgatcaaaatcagaatgct GCATACACTTAGCATGATAggatttttggtgacaaagcgtccccagacatttgtttca g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" S_feature complement(591895..592302) /Source="Nicolas_S_feature" /locus_tag="new_591895_592302_c" /HighExp="Paraq, H2O2, Oxctl, aero, LBGexp, dia15, GM 150, M/G, ferm, nit" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S187" promotor_-35 591912..591916 /Source="Nicolas_upshift_promotors" /id="U421" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.986013986013986" /psig=1 /xcortree=3115 /SigmaFactorBS="aacaaaagaaacaaatcagtgtgtaatagaaaaagcagatct tttaTGATCtgctcttttgctTATGGTAGTATTTAGAAGATgaagtcggcagttaaaa g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 591926 /Source="Nicolas_upshifts" /id="U421" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.986013986013986" /psig=1 /xcortree=3115 /SigmaFactorBS="aacaaaagaaacaaatcagtgtgtaatagaaaaagcagatct tttaTGATCtgctcttttgctTATGGTAGTATTTAGAAGATgaagtcggcagttaaaa g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 591929..591948 /Source="Nicolas_upshift_promotors" /id="U421" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.986013986013986" /psig=1 /xcortree=3115 /SigmaFactorBS="aacaaaagaaacaaatcagtgtgtaatagaaaaagcagatct tttaTGATCtgctcttttgctTATGGTAGTATTTAGAAGATgaagtcggcagttaaaa g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" downshifts complement(591940) /Source="Nicolas_upshifts" /id="D260" /incds=0 /nref=22 /ntot=134 /MaxReadThrough="-0.100210000000001" /MaxDrop="3.637" /score="4.29161871" /energy="-8.8" /TU="NA" /idTUdmin="U422" /TUdmin="-3" /isTUend="TRUE" CDS complement(592303..593205) /gene="cesA" /locus_tag="BSU_05440" /old_locus_tag="BSU05440" /EC_number="3.1.1.1" /function="16.8: Protect" /function="16.6: Maintain" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:7765103, 22248594, 24418394" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7765103, 22248594, 24418394; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="carboxylesterase NP" /protein_id="NP_388425.1" /db_xref="EnsemblGenomes-Gn:BSU05440" /db_xref="EnsemblGenomes-Tr:CAB12351" /db_xref="GOA:P96688" /db_xref="InterPro:IPR000073" /db_xref="InterPro:IPR029058" /db_xref="PDB:2R11" /db_xref="SubtiList:BG11957" /db_xref="UniProtKB/Swiss-Prot:P96688" /translation="MSNHSSSIPELSDNGIRYYQTYNESLSLWPVRCKSFYISTRFGQ THVIASGPEDAPPLVLLHGALFSSTMWYPNIADWSSKYRTYAVDIIGDKNKSIPENVS GTRTDYANWLLDVFDNLGIEKSHMIGLSLGGLHTMNFLLRMPERVKSAAILSPAETFL PFHHDFYKYALGLTASNGVETFLNWMMNDQNVLHPIFVKQFKAGVMWQDGSRNPNPNA DGFPYVFTDEELRSARVPILLLLGEHEVIYDPHSALHRASSFVPDIEAEVIKNAGHVL SMEQPTYVNERVMRFFNAETGISR*" gene complement(592303..593205) /gene="cesA" /locus_tag="BSU_05440" /old_locus_tag="BSU05440" S_feature complement(593206..593301) /Source="Nicolas_S_feature" /locus_tag="new_593206_593301_c" /HighExp="nit, ferm, aero, LoTm, M/G, GM 150, Diami, Paraq, dia15, LBGexp" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S188" promotor_-10 complement(593281..593300) /Source="Nicolas_upshift_promotors" /id="U422" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.834165834165834" /psig=1 /xcortree=2448 /SigmaFactorBS="tcaataatctgtttcaatcgtttttttccttttcatcttgGA TTTGACgtctaataacaacTGTATTATATTGTAAATAAAgtctgttatatcaaaatca g" /listShort="S188, nap, S187" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(593301) /Source="Nicolas_upshifts" /id="U422" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.834165834165834" /psig=1 /xcortree=2448 /SigmaFactorBS="tcaataatctgtttcaatcgtttttttccttttcatcttgGA TTTGACgtctaataacaacTGTATTATATTGTAAATAAAgtctgttatatcaaaatca g" /listShort="S188, nap, S187" /GFF_Attribute="listLong" promotor_-35 complement(593314..593321) /Source="Nicolas_upshift_promotors" /id="U422" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.834165834165834" /psig=1 /xcortree=2448 /SigmaFactorBS="tcaataatctgtttcaatcgtttttttccttttcatcttgGA TTTGACgtctaataacaacTGTATTATATTGTAAATAAAgtctgttatatcaaaatca g" /listShort="S188, nap, S187" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(593407..594096) /gene="ydfK" /locus_tag="BSU_05450" /old_locus_tag="BSU05450" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 10200972, 15849754, 16850406; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative integral inner membrane protein" /protein_id="NP_388426.1" /db_xref="EnsemblGenomes-Gn:BSU05450" /db_xref="EnsemblGenomes-Tr:CAB12352" /db_xref="GOA:P96689" /db_xref="InterPro:IPR007563" /db_xref="SubtiList:BG12158" /db_xref="UniProtKB/Swiss-Prot:P96689" /translation="MFGTIFNTVMIIAGSIIGGIFKKGIKDEYQDILMQAMGFAAVAL GINAITQHLPDSKYPILFIVSLAIGGLLGQIINLELRFNKLVNKFSKSNLAEGLSTAV LLFCIGSLSILGPVEAALHGDYTYLLTNGMLDGITSIVLASTFGFGIAAAALVLFSWQ GSIYLFAQVMESAINTDLINEITIVGGILILSSGLSILGIKKFKTLNLLPSLLIPPVV IFVIHAFGLRF*" gene complement(593407..594096) /gene="ydfK" /locus_tag="BSU_05450" /old_locus_tag="BSU05450" CDS complement(594186..594998) /gene="ydfL" /locus_tag="BSU_05460" /old_locus_tag="BSU05460" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative transcriptional regulator of efflux transporter" /protein_id="NP_388427.1" /db_xref="EnsemblGenomes-Gn:BSU05460" /db_xref="EnsemblGenomes-Tr:CAB12353" /db_xref="GOA:P96690" /db_xref="InterPro:IPR000551" /db_xref="InterPro:IPR009061" /db_xref="InterPro:IPR010499" /db_xref="InterPro:IPR011256" /db_xref="InterPro:IPR029442" /db_xref="SubtiList:BG12159" /db_xref="UniProtKB/Swiss-Prot:P96690" /translation="MKEFFSIGEVSKLFNVKISALRYYDEIGLLKPEYKDEQTNYRYY STQQFERLDTIKYLRALGLPINKLLDFYNSQNTNTLLHLLKSQQVEIDRKKKELERIE RKISRRITHIEDAVNMPLHQISKIKLPAMRVAYLQHEYVLGHDIEHSLAELRTHLNVN EDIFIGKIGLSISAANVKAKQFDKYSSIFMILEDENEKTSSEIIFPSREYLQIRFKGS HPEAEPYYKKLLAYMKEHHYEVAGDSIEITLIDYGITNNLDNYVTEILLPIK*" gene complement(594186..594998) /gene="ydfL" /locus_tag="BSU_05460" /old_locus_tag="BSU05460" promotor_-10 complement(595027..595046) /Source="Nicolas_upshift_promotors" /id="U423" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.911088911088911" /psig="0.998001998001998" /xcortree=1898 /SigmaFactorBS="tttttagaaggagttttttctttatgctgcaAACTTTACctt tagtactcgccgTACTATATAATGTGTGTATAtcaatcataggacagaaaggttgtta g" /listShort="ydfL" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(595040) /Source="Nicolas_upshifts" /id="U423" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.911088911088911" /psig="0.998001998001998" /xcortree=1898 /SigmaFactorBS="tttttagaaggagttttttctttatgctgcaAACTTTACctt tagtactcgccgTACTATATAATGTGTGTATAtcaatcataggacagaaaggttgtta g" /listShort="ydfL" /GFF_Attribute="listLong" promotor_-35 complement(595062..595069) /Source="Nicolas_upshift_promotors" /id="U423" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.911088911088911" /psig="0.998001998001998" /xcortree=1898 /SigmaFactorBS="tttttagaaggagttttttctttatgctgcaAACTTTACctt tagtactcgccgTACTATATAATGTGTGTATAtcaatcataggacagaaaggttgtta g" /listShort="ydfL" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(595109..596002) /gene="mneP" /locus_tag="BSU_05470" /old_locus_tag="BSU05470" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:27748968" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 27748968; Product type t: transporter" /codon_start=1 /transl_table=11 /product="primary Mn(II) efflux pump" /protein_id="NP_388428.2" /db_xref="EnsemblGenomes-Gn:BSU05470" /db_xref="EnsemblGenomes-Tr:CAB12354" /db_xref="GOA:C0SP78" /db_xref="InterPro:IPR002524" /db_xref="InterPro:IPR027469" /db_xref="InterPro:IPR027470" /db_xref="InterPro:IPR036837" /db_xref="SubtiList:BG12160" /db_xref="UniProtKB/Swiss-Prot:C0SP78" /translation="MASEREQISRKVALIALIANLILMAGKVFFGLVGDSEAVFADGI HSAADVVASIAVLAVIGISNKPPDQDHPFGHGKAEVISEAIVGIILVIVSVYILIEAI LSFVKGPSVPQYSALFAALISYVAKEILYRYSIKQGKKWNSKAIIAIAYDHKGDIVAS LAAFIGVLLAIIGNSRGWSYLLYADAIASAIVAYLIFKISMELIRPSVDVLMEKSVDP ELIEEYKAVIFQCDQVKRIDRIRAREHGHYKLLDVRLSLDHDLTIKQGHDIAREIRNE IKRQFSDVEEVLIHVNPYFEE*" gene complement(595109..596002) /gene="mneP" /locus_tag="BSU_05470" /old_locus_tag="BSU05470" downshifts complement(595129) /Source="Nicolas_upshifts" /id="D261" /incds=0 /nref=23 /ntot=121 /MaxReadThrough="1.07979" /MaxDrop="4.0938" /score="12.079524" /energy="-6.2" /TU="NA" /idTUdmin="U424" /TUdmin="-2" /isTUend="TRUE" S_feature complement(596003..596095) /Source="Nicolas_S_feature" /locus_tag="new_596003_596095_c" /HighExp="LPh, HPh, LPhT, UNK1, MG t5, MG 5, MG 15, BMM, GM 120, Fru" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S189" promotor_-10 complement(596076..596095) /Source="Nicolas_upshift_promotors" /id="U424" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.756243756243756" /psig=1 /xcortree=1748 /SigmaFactorBS="caccttatttattagtaaacaggaaacaacgttgcTATAGAC CcactcgaaattgaatTGGTATGATAAACAAAGTGAttacacaggaaaggatacggag a" /listShort="S189, ydfM" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(596093) /Source="Nicolas_upshifts" /id="U424" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.756243756243756" /psig=1 /xcortree=1748 /SigmaFactorBS="caccttatttattagtaaacaggaaacaacgttgcTATAGAC CcactcgaaattgaatTGGTATGATAAACAAAGTGAttacacaggaaaggatacggag a" /listShort="S189, ydfM" /GFF_Attribute="listLong" promotor_-35 complement(596111..596118) /Source="Nicolas_upshift_promotors" /id="U424" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.756243756243756" /psig=1 /xcortree=1748 /SigmaFactorBS="caccttatttattagtaaacaggaaacaacgttgcTATAGAC CcactcgaaattgaatTGGTATGATAAACAAAGTGAttacacaggaaaggatacggag a" /listShort="S189, ydfM" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 596284..596291 /Source="Nicolas_upshift_promotors" /id="U425" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.988011988011988" /psig=1 /xcortree=3024 /SigmaFactorBS="agtgaaaaatttccacctaattttcaaaaaccTATTGACAtg agaagatctgtaTTTTACTATTATCTCATATTcaagatattttaatttgagatatttg g" /listShort="ydfN, ydfO, S190, ydfP" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 596306..596325 /Source="Nicolas_upshift_promotors" /id="U425" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.988011988011988" /psig=1 /xcortree=3024 /SigmaFactorBS="agtgaaaaatttccacctaattttcaaaaaccTATTGACAtg agaagatctgtaTTTTACTATTATCTCATATTcaagatattttaatttgagatatttg g" /listShort="ydfN, ydfO, S190, ydfP" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 596312 /Source="Nicolas_upshifts" /id="U425" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.988011988011988" /psig=1 /xcortree=3024 /SigmaFactorBS="agtgaaaaatttccacctaattttcaaaaaccTATTGACAtg agaagatctgtaTTTTACTATTATCTCATATTcaagatattttaatttgagatatttg g" /listShort="ydfN, ydfO, S190, ydfP" /GFF_Attribute="listLong" CDS 596478..597098 /gene="ydfN" /locus_tag="BSU_05480" /old_locus_tag="BSU05480" /EC_number="1.-.-.-" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 17407181; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative oxidoreductase" /protein_id="NP_388429.1" /db_xref="EnsemblGenomes-Gn:BSU05480" /db_xref="EnsemblGenomes-Tr:CAB12355" /db_xref="GOA:P96692" /db_xref="InterPro:IPR000415" /db_xref="InterPro:IPR029479" /db_xref="PDB:3BEM" /db_xref="SubtiList:BG12161" /db_xref="UniProtKB/Swiss-Prot:P96692" /translation="MAEFTHLVNERRSASNFLSGHPITKEDLNEMFELVALAPSAFNL QHTKYVTVLDQDVKEKLKQAANGQYKVVSSSAVLLVLGDKQAYQQAADIYEGLKVLGI LNKQEYDHMVQDTVSFYENRGEQFKRDEAIRNASLSAMMFMLSAKEKGWDTCPMIGFD AEAVKRILNIDDQFEVVMMITIGKEKTESRRPRGYRKPVNEFVEYM*" gene 596478..597098 /gene="ydfN" /locus_tag="BSU_05480" /old_locus_tag="BSU05480" promotor_-35 596822..596828 /Source="Nicolas_upshift_promotors" /id="U426" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp="0.993006993006993" /psig="0.993006993006993" /xcortree=151 /SigmaFactorBS="tattggggatattaaataagcaagagtatgaccacatggtgc aagacacCGTTTCGttttatgaaaacaGGGGAGAACAATTTAAGAGagatgaggcgat a" /listShort="ydfO, S190, ydfP" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 596833 /Source="Nicolas_upshifts" /id="U426" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp="0.993006993006993" /psig="0.993006993006993" /xcortree=151 /SigmaFactorBS="tattggggatattaaataagcaagagtatgaccacatggtgc aagacacCGTTTCGttttatgaaaacaGGGGAGAACAATTTAAGAGagatgaggcgat a" /listShort="ydfO, S190, ydfP" /GFF_Attribute="listLong" promotor_-10 596842..596860 /Source="Nicolas_upshift_promotors" /id="U426" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp="0.993006993006993" /psig="0.993006993006993" /xcortree=151 /SigmaFactorBS="tattggggatattaaataagcaagagtatgaccacatggtgc aagacacCGTTTCGttttatgaaaacaGGGGAGAACAATTTAAGAGagatgaggcgat a" /listShort="ydfO, S190, ydfP" /GFF_Attribute="listLong" /label="promotor_-10" CDS 597114..598052 /gene="ydfO" /locus_tag="BSU_05490" /old_locus_tag="BSU05490" /EC_number="1.13.11.-" /function="16.8: Protect" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 17407181; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative dioxygenase" /protein_id="NP_388430.1" /db_xref="EnsemblGenomes-Gn:BSU05490" /db_xref="EnsemblGenomes-Tr:CAB12356" /db_xref="GOA:P96693" /db_xref="InterPro:IPR004360" /db_xref="InterPro:IPR029068" /db_xref="PDB:3OAJ" /db_xref="SubtiList:BG12162" /db_xref="UniProtKB/Swiss-Prot:P96693" /translation="MAKKTMGIHHITAIVGHPQENTDFYAGVLGLRLVKQTVNFDDPG TYHLYFGNEGGKPGTIITFFPWAGARQGVIGDGQVGVTSYVVPKGAMAFWEKRLEKFN VPYTKIERFGEQYVEFDDPHGLHLEIVEREEGEANTWTFGEVTPDVAIKGFGGATLLS EQPDKTADLLENIMGLERVGKEGDFVRYRSAGDIGNVIDLKLTPIGRGQMGAGTVHHI AWRANDDEDQLDWQRYIASHGYGVTPVRDRNYFNAIYFREHGEILFEIATDPPGFAHD ETQETMGEKLMLPVQYEPHRTQIEQGLLPFEVRELD*" gene 597114..598052 /gene="ydfO" /locus_tag="BSU_05490" /old_locus_tag="BSU05490" promotor_-35 598040..598043 /Source="Nicolas_upshift_promotors" /id="U427" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.658341658341658" /psig="0.658341658341658" /xcortree=729 /SigmaFactorBS="caaattgaacaagggctgctgccgtttgaagtaagAGAGtta gattgatttgaCACATAAAAAATAAAGAAACatatattcaattgatgattgctggatg g" /listShort="S190, ydfP" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 598058..598077 /Source="Nicolas_upshift_promotors" /id="U427" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.658341658341658" /psig="0.658341658341658" /xcortree=729 /SigmaFactorBS="caaattgaacaagggctgctgccgtttgaagtaagAGAGtta gattgatttgaCACATAAAAAATAAAGAAACatatattcaattgatgattgctggatg g" /listShort="S190, ydfP" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 598065..598153 /Source="Nicolas_S_feature" /locus_tag="new_598065_598153" /HighExp="Etha, BT, S6, S7, S8, G/S, GM 10, Gly, GM 15, B36" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigK, SigB, SigA" /TUshortPSig="0.658, 0.993, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S190" upshifts 598065 /Source="Nicolas_upshifts" /id="U427" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.658341658341658" /psig="0.658341658341658" /xcortree=729 /SigmaFactorBS="caaattgaacaagggctgctgccgtttgaagtaagAGAGtta gattgatttgaCACATAAAAAATAAAGAAACatatattcaattgatgattgctggatg g" /listShort="S190, ydfP" /GFF_Attribute="listLong" CDS 598154..598543 /gene="ydfP" /locus_tag="BSU_05500" /old_locus_tag="BSU05500" /EC_number="1.-.-.-" /function="16.8: Protect" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15306018, 15849754, 16850406, 17407181; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative membrane bound oxidoreductase" /protein_id="NP_388431.1" /db_xref="EnsemblGenomes-Gn:BSU05500" /db_xref="EnsemblGenomes-Tr:CAB12357" /db_xref="GOA:P96694" /db_xref="InterPro:IPR032808" /db_xref="SubtiList:BG12163" /db_xref="UniProtKB/Swiss-Prot:P96694" /translation="MEDAGLLLIRIMIGVVFLFYGTQKLFGWFGGYGIKGTGQWFESI GVKPGNVAAALSGLGELVSGILFILGVFLPLGAAIITIIMLGAIVKVHGAKGFANGAG GFEYNLVLIAVSIGVALIGSGAYALHF*" gene 598154..598543 /gene="ydfP" /locus_tag="BSU_05500" /old_locus_tag="BSU05500" downshifts 598534 /Source="Nicolas_upshifts" /id="D262" /incds=0 /nref=3 /ntot=91 /MaxReadThrough="1.0642" /MaxDrop="3.85597" /score="-8.69038499" /energy="-9.3" /TU="NA" /idTUdmin="U427" /TUdmin=29 /isTUend="FALSE" misc_feature 598657..598676 /Source="Nicolas_upshift_promotors" /id="U428" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.665334665334665" /psig="0.946053946053946" /xcortree=2048 /SigmaFactorBS="cattttcggcaagcttgcaggtactctgcaaagcaaaaaagc ggatatcataaatataAATCTGTATAGTGAATGATAcgtattgatgagcttggtcatg a" /listShort="S191, ydfQ" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" S_feature 598659..598728 /Source="Nicolas_S_feature" /locus_tag="new_598659_598728" /HighExp="Diami, dia5, H2O2, dia15, Etha, S8, Paraq, Salt, LPhT, G180" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.946" /TUlongSig="NA" /TUlongPSig="NA" /label="S191" upshifts 598659 /Source="Nicolas_upshifts" /id="U428" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.665334665334665" /psig="0.946053946053946" /xcortree=2048 /SigmaFactorBS="cattttcggcaagcttgcaggtactctgcaaagcaaaaaagc ggatatcataaatataAATCTGTATAGTGAATGATAcgtattgatgagcttggtcatg a" /listShort="S191, ydfQ" /GFF_Attribute="listLong" CDS 598729..599067 /gene="ydfQ" /locus_tag="BSU_05510" /old_locus_tag="BSU05510" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15937154; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative thioredoxin or thiol-disulfide isomerase" /protein_id="NP_388432.1" /db_xref="EnsemblGenomes-Gn:BSU05510" /db_xref="EnsemblGenomes-Tr:CAB12358" /db_xref="GOA:P96695" /db_xref="InterPro:IPR013766" /db_xref="InterPro:IPR036249" /db_xref="SubtiList:BG12164" /db_xref="UniProtKB/Swiss-Prot:P96695" /translation="MKEMTGLHSLVSIENFIKQHKFSFIYISRPGCTVCHAVLPQLRI VLDQFPNIKLGHINADDVAEVAGRFSVFTVPVLLLFIDGTEFLREARFVHFEQLEQKL KRVYRLYEGE*" gene 598729..599067 /gene="ydfQ" /locus_tag="BSU_05510" /old_locus_tag="BSU05510" downshifts 599055 /Source="Nicolas_upshifts" /id="D263" /incds=0 /nref=9 /ntot=28 /MaxReadThrough="1.76745" /MaxDrop="4.78737" /score="17.861178" /energy="-6" /TU="NA" /idTUdmin="U428" /TUdmin=0 /isTUend="TRUE" CDS complement(599107..599343) /gene="ydzH" /locus_tag="BSU_05520" /old_locus_tag="BSU05520" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein, sporulation-related" /protein_id="NP_388433.1" /db_xref="EnsemblGenomes-Gn:BSU05520" /db_xref="EnsemblGenomes-Tr:CAB12359" /db_xref="InterPro:IPR019618" /db_xref="SubtiList:BG12810" /db_xref="UniProtKB/Swiss-Prot:O31496" /translation="MRSQINISNLTINGMTQNANTDIGQNLQNSHTANSKNYGVNFTL GDYSPSHSIIISASCDNDTSDQGQVDNPSSPSEE*" gene complement(599107..599343) /gene="ydzH" /locus_tag="BSU_05520" /old_locus_tag="BSU05520" downshifts complement(599131) /Source="Nicolas_upshifts" /id="D264" /incds=0 /nref=1 /ntot=10 /MaxReadThrough="3.87679" /MaxDrop="2.5881" /score="9.38580075" /energy="-6" /TU="NA" /idTUdmin="U430" /TUdmin=418 /isTUend="FALSE" promotor_-35 599155..599161 /Source="Nicolas_upshift_promotors" /id="U429" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.722277722277722" /psig="0.722277722277722" /xcortree=1208 /SigmaFactorBS="aagggttatcaacctgcccttgatcactTGTATCAttatcac aacttgcTGAAATAATAATtgaatgagaaggagagtaatctcctaatgtgaaattcac t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 599176..599187 /Source="Nicolas_upshift_promotors" /id="U429" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.722277722277722" /psig="0.722277722277722" /xcortree=1208 /SigmaFactorBS="aagggttatcaacctgcccttgatcactTGTATCAttatcac aacttgcTGAAATAATAATtgaatgagaaggagagtaatctcctaatgtgaaattcac t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 599187 /Source="Nicolas_upshifts" /id="U429" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.722277722277722" /psig="0.722277722277722" /xcortree=1208 /SigmaFactorBS="aagggttatcaacctgcccttgatcactTGTATCAttatcac aacttgcTGAAATAATAATtgaatgagaaggagagtaatctcctaatgtgaaattcac t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" S_feature complement(599344..599505) /Source="Nicolas_S_feature" /locus_tag="new_599344_599505_c" /HighExp="BT, B36, S8, S7, G135, S5, S6, G180, Pyr, LBGstat" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="NA" /TUshortPSig="NA" /TUlongSig="NA" /TUlongPSig="NA" /label="S192" S_feature complement(599509..599874) /Source="Nicolas_S_feature" /locus_tag="new_599509_599874_c" /HighExp="BT, B36, S8, S7, S6, G/S, S5, Pyr, B60, S4" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigK, SigGF, SigK" /TUshortPSig="0.994, 0.989, 0.997" /TUlongSig="NA" /TUlongPSig="NA" /label="S193" downshifts complement(599549) /Source="Nicolas_upshifts" /id="D265" /incds=0 /nref=26 /ntot=52 /MaxReadThrough="2.64253" /MaxDrop="4.6761" /score="8.29803249" /energy="-12.4" /TU="NA" /idTUdmin="U430" /TUdmin=0 /isTUend="TRUE" CDS complement(599875..600105) /gene="ydzR" /locus_tag="BSU_05529" /old_locus_tag="BSU05529" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 19383706, 20709900" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein, sporulation-related" /protein_id="YP_003097687.1" /db_xref="EnsemblGenomes-Gn:BSU05529" /db_xref="EnsemblGenomes-Tr:CAX52560" /db_xref="InterPro:IPR019618" /db_xref="UniProtKB/Swiss-Prot:C0H3W2" /translation="MMKFPVYIHSISGNSVFNNGFAVSISPFSVSKTTEGSGGSNTGL VFESNALSQTSSANQAQNVTYAIQELLSKLLA*" gene complement(599875..600105) /gene="ydzR" /locus_tag="BSU_05529" /old_locus_tag="BSU05529" downshifts 600089 /Source="Nicolas_upshifts" /id="D266" /incds=0 /nref=1 /ntot=4 /MaxReadThrough="1.08051" /MaxDrop="3.36374" /score="17.861178" /energy="-6" /TU="NA" /idTUdmin="U428" /TUdmin=1034 /isTUend="FALSE" promotor_-10 complement(600126..600145) /Source="Nicolas_upshift_promotors" /id="U430" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.994005994005994" /psig="0.994005994005994" /xcortree=1432 /SigmaFactorBS="ggtttttgtctcttactgaaagtttttgccgttttGTTTAAG CAActgctgctcacacACCATATTGTATAAACAGTCataacagagaggagagatgaat g" /listShort="ydzR, S193" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(600143) /Source="Nicolas_upshifts" /id="U430" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.994005994005994" /psig="0.994005994005994" /xcortree=1432 /SigmaFactorBS="ggtttttgtctcttactgaaagtttttgccgttttGTTTAAG CAActgctgctcacacACCATATTGTATAAACAGTCataacagagaggagagatgaat g" /listShort="ydzR, S193" /GFF_Attribute="listLong" S_feature complement(600145..600228) /Source="Nicolas_S_feature" /locus_tag="new_600145_600228_c" /HighExp="S8, S5, S7, S6, S4, nit, ferm, BT, Pyr, G/S" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigGF, SigK" /TUshortPSig="0.989, 0.997" /TUlongSig="NA" /TUlongPSig="NA" /label="S194" promotor_-35 complement(600159..600168) /Source="Nicolas_upshift_promotors" /id="U430" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.994005994005994" /psig="0.994005994005994" /xcortree=1432 /SigmaFactorBS="ggtttttgtctcttactgaaagtttttgccgttttGTTTAAG CAActgctgctcacacACCATATTGTATAAACAGTCataacagagaggagagatgaat g" /listShort="ydzR, S193" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(600229..600906) /gene="ydfR" /locus_tag="BSU_05530" /old_locus_tag="BSU05530" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved membrane protein of unknown function" /protein_id="NP_388434.1" /db_xref="EnsemblGenomes-Gn:BSU05530" /db_xref="EnsemblGenomes-Tr:CAB12360" /db_xref="GOA:P96696" /db_xref="InterPro:IPR007353" /db_xref="InterPro:IPR023090" /db_xref="SubtiList:BG12165" /db_xref="UniProtKB/Swiss-Prot:P96696" /translation="MNRLPFGYIKLRLAGRKANPMTNLIHHWSGGSMNFTWESLVLIV AGVILLRISGRKSIAQMTSTQTVVMISIGTIIVQPIIEYSLFKTLIAAAIFTSTLIVM EWIQMKSNTIEKMLTGKAKIVIENGQLHIENLKKMRLTADQLEMQLRLHGVTAIQDVK IATLEANGQLGIELTDDAKPLTVRDLKKLIHPDFINKDGQAQSGNQNIFDEVGKKNKK NVPKKLH*" gene complement(600229..600906) /gene="ydfR" /locus_tag="BSU_05530" /old_locus_tag="BSU05530" promotor_-10 complement(600877..600888) /Source="Nicolas_upshift_promotors" /id="U431" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp="0.98901098901099" /psig="0.98901098901099" /xcortree=782 /SigmaFactorBS="taatatatccatctataccaaaaatattgttcggttcaggac AGAATGAaccgactgcctttcGGATATATTAAAttgcgattggccggaagaaaagcca a" /listShort="ydfR, S194, ydzR, S193" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(600891) /Source="Nicolas_upshifts" /id="U431" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp="0.98901098901099" /psig="0.98901098901099" /xcortree=782 /SigmaFactorBS="taatatatccatctataccaaaaatattgttcggttcaggac AGAATGAaccgactgcctttcGGATATATTAAAttgcgattggccggaagaaaagcca a" /listShort="ydfR, S194, ydzR, S193" /GFF_Attribute="listLong" promotor_-35 complement(600903..600909) /Source="Nicolas_upshift_promotors" /id="U431" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp="0.98901098901099" /psig="0.98901098901099" /xcortree=782 /SigmaFactorBS="taatatatccatctataccaaaaatattgttcggttcaggac AGAATGAaccgactgcctttcGGATATATTAAAttgcgattggccggaagaaaagcca a" /listShort="ydfR, S194, ydzR, S193" /GFF_Attribute="listLong" /label="promotor_-35" S_feature complement(600907..601740) /Source="Nicolas_S_feature" /locus_tag="new_600907_601740_c" /HighExp="S6, S8, S7, S5, BT, B36, G/S, Pyr, nit, B60" /AntisenseName="ydfS" /AntisenseCor="0.65823831974361602" /AntisenseRegPval="-34.1" /CDS_PredictionProba="NA" /TUshortSig="SigK" /TUshortPSig="0.997" /TUlongSig="NA" /TUlongPSig="NA" /label="S195" promotor_-35 600922..600927 /Source="Nicolas_upshift_promotors" /id="U432" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp="0.944055944055944" /psig="0.944055944055944" /xcortree=781 /SigmaFactorBS="ccgaaaggcagtcggttcattctgtcctgaaccgaACAATAt ttttggtatagatGGATATATTAAGccaaacaatgatagcaacaggagttttttggcc g" /listShort="ydfS" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 600942..600953 /Source="Nicolas_upshift_promotors" /id="U432" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp="0.944055944055944" /psig="0.944055944055944" /xcortree=781 /SigmaFactorBS="ccgaaaggcagtcggttcattctgtcctgaaccgaACAATAt ttttggtatagatGGATATATTAAGccaaacaatgatagcaacaggagttttttggcc g" /listShort="ydfS" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 600947 /Source="Nicolas_upshifts" /id="U432" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp="0.944055944055944" /psig="0.944055944055944" /xcortree=781 /SigmaFactorBS="ccgaaaggcagtcggttcattctgtcctgaaccgaACAATAt ttttggtatagatGGATATATTAAGccaaacaatgatagcaacaggagttttttggcc g" /listShort="ydfS" /GFF_Attribute="listLong" CDS 601019..601726 /gene="ydfS" /locus_tag="BSU_05540" /old_locus_tag="BSU05540" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_388435.1" /db_xref="EnsemblGenomes-Gn:BSU05540" /db_xref="EnsemblGenomes-Tr:CAB12361" /db_xref="GOA:P96697" /db_xref="InterPro:IPR007353" /db_xref="InterPro:IPR023090" /db_xref="SubtiList:BG12166" /db_xref="UniProtKB/Swiss-Prot:P96697" /translation="MIELEVVIRTVASFGLLLIAERILGKQTISQMTIFDFIAAITLG AIAAGLAYNTSIKPHNMAISFSIFVLTIFLISFLSIKNRKLRKFFAGDPTVLIQNGKI LESNMRKMRYTLDYLNQQLREKEIFNIEEVLFAILETNGQLTVLRKPQFRHVTKQDLM IAVNQEQRLPIELIMDGEIIENNLKQNRLTESWLLEELRKRDIKVKETVYAVLLGNGD IYVDQYKDHISVPMDKE*" gene 601019..601726 /gene="ydfS" /locus_tag="BSU_05540" /old_locus_tag="BSU05540" CDS complement(601741..602172) /gene="cotP" /locus_tag="BSU_05550" /old_locus_tag="BSU05550" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:11150673" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11150673; Product type s: structure" /codon_start=1 /transl_table=11 /product="spore coat protein" /protein_id="NP_388436.1" /db_xref="EnsemblGenomes-Gn:BSU05550" /db_xref="EnsemblGenomes-Tr:CAB12362" /db_xref="GOA:P96698" /db_xref="InterPro:IPR002068" /db_xref="InterPro:IPR008978" /db_xref="InterPro:IPR031107" /db_xref="SubtiList:BG12167" /db_xref="UniProtKB/Swiss-Prot:P96698" /translation="MDFEKIRKWLEITNEYKQSDFWTNVLKYKAPEHFFDSEASTFVY DFYQDEEYNFIIVEMPGVYEEELTIRLLSKTQLLIKGTITPVFPAEMEVLRERYYGEI ERIIQLPEAAETHLLQIQLLNGLLHISYPRQVETVAFNKGL*" gene complement(601741..602172) /gene="cotP" /locus_tag="BSU_05550" /old_locus_tag="BSU05550" CDS complement(602185..602427) /gene="ydgA" /locus_tag="BSU_05560" /old_locus_tag="BSU05560" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein; putative germination protein" /protein_id="NP_388437.1" /db_xref="EnsemblGenomes-Gn:BSU05560" /db_xref="EnsemblGenomes-Tr:CAB12363" /db_xref="InterPro:IPR019618" /db_xref="SubtiList:BG12168" /db_xref="UniProtKB/Swiss-Prot:P96699" /translation="MPYQINIANIKINGVTQNGNIDVGPTVHNSHTANSKYFGANFSL GDLSPTSSLLNTGNIDSDVSDQDQIGNPSAPISNQI*" gene complement(602185..602427) /gene="ydgA" /locus_tag="BSU_05560" /old_locus_tag="BSU05560" CDS complement(602441..602713) /gene="ydgB" /locus_tag="BSU_05570" /old_locus_tag="BSU05570" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein; putative germination protein" /protein_id="NP_388438.1" /db_xref="EnsemblGenomes-Gn:BSU05570" /db_xref="EnsemblGenomes-Tr:CAB12364" /db_xref="InterPro:IPR019618" /db_xref="SubtiList:BG12169" /db_xref="UniProtKB/Swiss-Prot:P96700" /translation="MPSTVINLYYLKINSISGNGSITIGEAAYNSPTNNQKSQGTNSS FGDTSPTESVMENFLNDPDVNDQTSIGNSDTSNVNAPPIAPPPILD*" gene complement(602441..602713) /gene="ydgB" /locus_tag="BSU_05570" /old_locus_tag="BSU05570" promotor_-10 complement(602735..602754) /Source="Nicolas_upshift_promotors" /id="U433" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=1305 /SigmaFactorBS="gatagagttttgcccgtaaatgCAAGGAACAAttgggtgcag cggCGCATAATGTACTGTACAGAaagatggaagggtgtgatgggatgccgtctacagt a" /listShort="ydgB, ydgA, cotP, S195, ydfR, S194, ydzR, S193" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(602739) /Source="Nicolas_upshifts" /id="U433" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=1305 /SigmaFactorBS="gatagagttttgcccgtaaatgCAAGGAACAAttgggtgcag cggCGCATAATGTACTGTACAGAaagatggaagggtgtgatgggatgccgtctacagt a" /listShort="ydgB, ydgA, cotP, S195, ydfR, S194, ydzR, S193" /GFF_Attribute="listLong" promotor_-35 complement(602768..602777) /Source="Nicolas_upshift_promotors" /id="U433" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=1305 /SigmaFactorBS="gatagagttttgcccgtaaatgCAAGGAACAAttgggtgcag cggCGCATAATGTACTGTACAGAaagatggaagggtgtgatgggatgccgtctacagt a" /listShort="ydgB, ydgA, cotP, S195, ydfR, S194, ydzR, S193" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 602932..602939 /Source="Nicolas_upshift_promotors" /id="U434" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.786213786213786" /psig="0.997002997002997" /xcortree=1917 /SigmaFactorBS="gaagctggcaaacaggatcagtttgaaatAATTGACAatgaa gctaatgccaTGAAATAATACTCGTGAGTAacattactcgtgggtattatttttgggg t" /listShort="ydgC, ydgD, S196, ydgE, S197" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 602955..602974 /Source="Nicolas_upshift_promotors" /id="U434" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.786213786213786" /psig="0.997002997002997" /xcortree=1917 /SigmaFactorBS="gaagctggcaaacaggatcagtttgaaatAATTGACAatgaa gctaatgccaTGAAATAATACTCGTGAGTAacattactcgtgggtattatttttgggg t" /listShort="ydgC, ydgD, S196, ydgE, S197" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 602963 /Source="Nicolas_upshifts" /id="U434" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.786213786213786" /psig="0.997002997002997" /xcortree=1917 /SigmaFactorBS="gaagctggcaaacaggatcagtttgaaatAATTGACAatgaa gctaatgccaTGAAATAATACTCGTGAGTAacattactcgtgggtattatttttgggg t" /listShort="ydgC, ydgD, S196, ydgE, S197" /GFF_Attribute="listLong" CDS 603012..603599 /gene="ydgC" /locus_tag="BSU_05580" /old_locus_tag="BSU05580" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative transcriptional regulator" /protein_id="NP_388439.1" /db_xref="EnsemblGenomes-Gn:BSU05580" /db_xref="EnsemblGenomes-Tr:CAB12365" /db_xref="GOA:P96701" /db_xref="InterPro:IPR001647" /db_xref="InterPro:IPR009057" /db_xref="InterPro:IPR036271" /db_xref="SubtiList:BG12170" /db_xref="UniProtKB/Swiss-Prot:P96701" /translation="MKSKGVESRKRLLKAAANEFSVRGFHDAKVSEIVKKAGFTQPSF YLYFQSKEAIFAELITDFHSRVRKLTESLLLENGLNTEDVSKRVLLAVETVFQFLDED KDLTKIGFFLNPEAKQMKKDLAMVLKENLEAEQRLGYFHSELDMETVAECLVGMIEHL TESFLLTGIKDPASLAAEVVNLLIYGMLPKGNDVR*" gene 603012..603599 /gene="ydgC" /locus_tag="BSU_05580" /old_locus_tag="BSU05580" CDS 603596..603940 /gene="ydgD" /locus_tag="BSU_05590" /old_locus_tag="BSU05590" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_388440.1" /db_xref="EnsemblGenomes-Gn:BSU05590" /db_xref="EnsemblGenomes-Tr:CAB12366" /db_xref="GOA:P96702" /db_xref="InterPro:IPR032808" /db_xref="SubtiList:BG12171" /db_xref="UniProtKB/Swiss-Prot:P96702" /translation="MISIMMKVSLAVFMLAGGIIKVSRVPFQVEHWRHYQYPLWFLTV TGILEIAGALAMTAGIWNRYAAIGAGVLFVVLMAGAIHAHMFRARQSVIMAIQAMICL IVSIMIIMGSYT*" gene 603596..603940 /gene="ydgD" /locus_tag="BSU_05590" /old_locus_tag="BSU05590" S_feature 603941..604102 /Source="Nicolas_S_feature" /locus_tag="new_603941_604102" /HighExp="Salt, Diami, dia15, dia5, aero, H2O2, SMMPr, Etha, Lbtran, LBGstat" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.997" /TUlongSig="NA" /TUlongPSig="NA" /label="S196" CDS 604103..604576 /gene="ydgE" /locus_tag="BSU_05600" /old_locus_tag="BSU05600" /EC_number="2.3.1.-" /function="16.11: Scavenge (Catabolism)" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative N-acetyltransferase" /protein_id="NP_388441.1" /db_xref="EnsemblGenomes-Gn:BSU05600" /db_xref="EnsemblGenomes-Tr:CAB12367" /db_xref="GOA:P96703" /db_xref="InterPro:IPR000182" /db_xref="InterPro:IPR016181" /db_xref="SubtiList:BG12172" /db_xref="UniProtKB/Swiss-Prot:P96703" /translation="MAFTLEDMTEEEFEAFRGMSVQNFAKQNITSGTWTEKEAFEKSE QAYENMIPNGRDSSNHYFWNITNDQGERMGWLWLYADPLHPQKEAFIYSFGLYEAFRG KGLAQLALQTLDERARELGAERLALHVFAHNETAVYLYQKMGYAMTNIRMRKQLC*" gene 604103..604576 /gene="ydgE" /locus_tag="BSU_05600" /old_locus_tag="BSU05600" S_feature 604577..605269 /Source="Nicolas_S_feature" /locus_tag="new_604577_605269" /HighExp="Salt, H2O2, dia15, aero, T-2.40H, Diami, T-3.40H, T-1.40H, T-4.40H, T-0.40H" /AntisenseName="vmlR" /AntisenseCor="-7.1224465259194999E-2" /AntisenseRegPval="-0.6" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.997" /TUlongSig="NA" /TUlongPSig="NA" /label="S197" downshifts complement(604719) /Source="Nicolas_upshifts" /id="D267" /incds=0 /nref=4 /ntot=88 /MaxReadThrough="0.39199" /MaxDrop="3.39645" /score="18.2783449" /energy="-8.8" /TU="NA" /idTUdmin="U436" /TUdmin=0 /isTUend="TRUE" CDS complement(604736..606379) /gene="vmlR" /locus_tag="BSU_05610" /old_locus_tag="BSU05610" /function="16.1: Circulate" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:16109936, 22226636, 24687494, 25891423" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16109936, 22226636, 24687494, 25891423; Product type t: transporter" /codon_start=1 /transl_table=11 /product="ATP-binding cassette efflux transporter" /protein_id="NP_388442.1" /db_xref="EnsemblGenomes-Gn:BSU05610" /db_xref="EnsemblGenomes-Tr:CAB12368" /db_xref="GOA:P39115" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR032781" /db_xref="SubtiList:BG10767" /db_xref="UniProtKB/Swiss-Prot:P39115" /translation="MKEIVTLTNVSYEVKDQTVFKHVNASVQQGDIIGIIGKNGAGKS TLLHLIHNDLAPAQGQILRKDIKLALVEQETAAYSFADQTPAEKKLLEKWHVPLRDFH QLSGGEKLKARLAKGLSEDADLLLLDEPTNHLDEKSLQFLIQQLKHYNGTVILVSHDR YFLDEAATKIWSLEDQTLIEFKGNYSGYMKFREKKRLTQQREYEKQQKMVERIEAQMN GLASWSEKAHAQSTKKEGFKEYHRVKAKRTDAQIKSKQKRLEKELEKAKAEPVTPEYT VRFSIDTTHKTGKRFLEVQNVTKAFGERTLFKNANFTIQHGEKVAIIGPNGSGKTTLL NIILGQETAEGSVWVSPSANIGYLTQEVFDLPLEQTPEELFENETFKARGHVQNLMRH LGFTAAQWTEPIKHMSMGERVKIKLMAYILEEKDVLILDEPTNHLDLPSREQLEETLS QYSGTLLAVSHDRYFLEKTTNSKLVISNNGIEKQLNDVPSERNEREELRLKLETERQE VLGKLSFMTPNDKGYKELDQAFNELTKRIKELDHQDKKD*" gene complement(604736..606379) /gene="vmlR" /locus_tag="BSU_05610" /old_locus_tag="BSU05610" S_feature complement(606414..606611) /Source="Nicolas_S_feature" /locus_tag="new_606414_606611_c" /HighExp="BC, Sw, B60, B36, LoTm, S7, HiOs, S4, BI, M9-stat" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S198" promotor_-35 606428..606430 /Source="Nicolas_upshift_promotors" /id="U435" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.433566433566434" /psig="0.494505494505494" /xcortree=34 /SigmaFactorBS="gctttaaagggagaataaaaaaatcctcccaaatgtgTTGga aggattagccgtgcCTGTGCATGATCAAATAAGctattttttataaatagcagtgtcg t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 606447..606465 /Source="Nicolas_upshift_promotors" /id="U435" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.433566433566434" /psig="0.494505494505494" /xcortree=34 /SigmaFactorBS="gctttaaagggagaataaaaaaatcctcccaaatgtgTTGga aggattagccgtgcCTGTGCATGATCAAATAAGctattttttataaatagcagtgtcg t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 606451 /Source="Nicolas_upshifts" /id="U435" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.433566433566434" /psig="0.494505494505494" /xcortree=34 /SigmaFactorBS="gctttaaagggagaataaaaaaatcctcccaaatgtgTTGga aggattagccgtgcCTGTGCATGATCAAATAAGctattttttataaatagcagtgtcg t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" downshifts complement(606457) /Source="Nicolas_upshifts" /id="D268" /incds=0 /nref=210 /ntot=265 /MaxReadThrough="3.59768" /MaxDrop="6.27457" /score="29.5863709" /energy="-11.8" /TU="U436" /idTUdmin="U437" /TUdmin=242 /isTUend="FALSE" downshifts 606577 /Source="Nicolas_upshifts" /id="D269" /incds=0 /nref=35 /ntot=150 /MaxReadThrough="1.71902" /MaxDrop="4.95368" /score="-7.23582918" /energy="-13.3" /TU="NA" /idTUdmin="U435" /TUdmin="-2" /isTUend="TRUE" promotor_-10 complement(606603..606622) /Source="Nicolas_upshift_promotors" /id="U436" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.717282717282717" /psig=1 /xcortree=414 /SigmaFactorBS="atgagagcaggagtttttttgatgaaaatgaccTTTGCTTTt gaatttaaaggTATGCTATAGTGTTTGTAATcaaaacaagaagggatgatgggtggac a" /listShort="S198, vmlR" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(606615) /Source="Nicolas_upshifts" /id="U436" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.717282717282717" /psig=1 /xcortree=414 /SigmaFactorBS="atgagagcaggagtttttttgatgaaaatgaccTTTGCTTTt gaatttaaaggTATGCTATAGTGTTTGTAATcaaaacaagaagggatgatgggtggac a" /listShort="S198, vmlR" /GFF_Attribute="listLong" promotor_-35 complement(606635..606642) /Source="Nicolas_upshift_promotors" /id="U436" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.717282717282717" /psig=1 /xcortree=414 /SigmaFactorBS="atgagagcaggagtttttttgatgaaaatgaccTTTGCTTTt gaatttaaaggTATGCTATAGTGTTTGTAATcaaaacaagaagggatgatgggtggac a" /listShort="S198, vmlR" /GFF_Attribute="listLong" /label="promotor_-35" downshifts complement(606698) /Source="Nicolas_upshifts" /id="D270" /incds=0 /nref=92 /ntot=203 /MaxReadThrough="2.22553" /MaxDrop="5.71399" /score="18.9878298" /energy="-13.3" /TU="NA" /idTUdmin="U437" /TUdmin=1 /isTUend="TRUE" CDS complement(606699..608075) /gene="ydgF" /locus_tag="BSU_05620" /old_locus_tag="BSU05620" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16109936, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative amino acid permease" /protein_id="NP_388443.1" /db_xref="EnsemblGenomes-Gn:BSU05620" /db_xref="EnsemblGenomes-Tr:CAB12369" /db_xref="GOA:P96704" /db_xref="InterPro:IPR002293" /db_xref="InterPro:IPR004840" /db_xref="InterPro:IPR004841" /db_xref="SubtiList:BG12173" /db_xref="UniProtKB/Swiss-Prot:P96704" /translation="MTDDMTKDNINQQTLQRGLKNRHIQLIAIGGAIGTGLFLGSGKS IHFAGPSILFAYMITGIICFLIMRSLGELLLSNLNYHSFVDFVQDYLGDMAAFITGWT YWFCWISIAMADLTAVGLYTQYWLPGVPQWVPGLIALIILLIMNLATVKLFGELEFWF ALIKVIAILALIVIGLVMIFKGFSTSSGVSSFTNLWSHGGLFPNGMHGFILSFQMVVF AFVGIELVGLTAGETENPEKVIPKAINNIPVRVLLFYIGALLVIMSIYPWDIINPSES PFVQVFVAVGIVGAASIINFVVLTSAASACNSAVFSTSRMVYSLAKDHNAPESMAKLT QRKVPRNALFFSAIVILIGVTLNYIMPEGVFTLITSISTVCFIYIWGITVICHMKYRK TRPELAKTNKFKLPLYPFTNYLILAFLAFVLVVLALAQDTRVSLFVTPVWFILLIVIY KVRKAKHQ*" gene complement(606699..608075) /gene="ydgF" /locus_tag="BSU_05620" /old_locus_tag="BSU05620" misc_feature complement(608125..608144) /Source="Nicolas_upshift_promotors" /id="U437" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.897102897102897" /psig=1 /xcortree=1890 /SigmaFactorBS="aatcacattaaaattcttttcatcaatccttttttagtaaaa aagatagaaattttAGTGTTATAATAATCATTAAaaatagattgctgactcaataaac a" /listShort="ydgF" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(608140) /Source="Nicolas_upshifts" /id="U437" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.897102897102897" /psig=1 /xcortree=1890 /SigmaFactorBS="aatcacattaaaattcttttcatcaatccttttttagtaaaa aagatagaaattttAGTGTTATAATAATCATTAAaaatagattgctgactcaataaac a" /listShort="ydgF" /GFF_Attribute="listLong" CDS complement(608246..608764) /gene="dinB" /locus_tag="BSU_05630" /old_locus_tag="BSU05630" /function="16.8: Protect" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2b: Function from indirect experimental evidences (e.g. phenotypes); PubMedId: 1847907, 3110138, 12644484, 16267290, 22059487; Product type r: regulator" /codon_start=1 /transl_table=11 /product="nuclease inhibitor" /protein_id="NP_388444.1" /db_xref="EnsemblGenomes-Gn:BSU05630" /db_xref="EnsemblGenomes-Tr:CAB12370" /db_xref="GOA:Q02886" /db_xref="InterPro:IPR007837" /db_xref="InterPro:IPR034660" /db_xref="SubtiList:BG10539" /db_xref="UniProtKB/Swiss-Prot:Q02886" /translation="MSDFAFKLYEYNVWANQQIFNRLKELPKEIYHQEIQSVFPSISH VLSHVYLSDLGWIEVFSGKTLSDALALAEQLKEQTEAKEIEEMEDLFLRLSERYILFL QQKEQLNKPLQIQNPSSGIMKTTVSELLPHVVNHGTYHRGNITAMLRQAGYASAPTDY GLYLFMTKTEKA*" gene complement(608246..608764) /gene="dinB" /locus_tag="BSU_05630" /old_locus_tag="BSU05630" downshifts complement(608260) /Source="Nicolas_upshifts" /id="D271" /incds=0 /nref=35 /ntot=176 /MaxReadThrough="2.77148" /MaxDrop="6.32316" /score="16.2748201" /energy="-15" /TU="NA" /idTUdmin="U438" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(608790..608809) /Source="Nicolas_upshift_promotors" /id="U438" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.839160839160839" /psig=1 /xcortree=1506 /SigmaFactorBS="tcctctaaactatatatgtcaacaaattttattttcgagcaC TCTacataagaactcatgTTCGTGTATAATGAAAGCTAtacacacgaaagggggaatt t" /listShort="dinB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(608809) /Source="Nicolas_upshifts" /id="U438" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.839160839160839" /psig=1 /xcortree=1506 /SigmaFactorBS="tcctctaaactatatatgtcaacaaattttattttcgagcaC TCTacataagaactcatgTTCGTGTATAATGAAAGCTAtacacacgaaagggggaatt t" /listShort="dinB" /GFF_Attribute="listLong" promotor_-35 complement(608825..608828) /Source="Nicolas_upshift_promotors" /id="U438" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.839160839160839" /psig=1 /xcortree=1506 /SigmaFactorBS="tcctctaaactatatatgtcaacaaattttattttcgagcaC TCTacataagaactcatgTTCGTGTATAATGAAAGCTAtacacacgaaagggggaatt t" /listShort="dinB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 608846..608853 /Source="Nicolas_upshift_promotors" /id="U439" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.528471528471528" /psig="0.97002997002997" /xcortree=2440 /SigmaFactorBS="gagtgctcgaaaataaaattTGTTGACAtatatagtttagag GAATAAACTAATTGACATTGaacataaagtttagcggggtaaactataatgaggaggg g" /listShort="ydgG, ydgH" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 608868..608887 /Source="Nicolas_upshift_promotors" /id="U439" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.528471528471528" /psig="0.97002997002997" /xcortree=2440 /SigmaFactorBS="gagtgctcgaaaataaaattTGTTGACAtatatagtttagag GAATAAACTAATTGACATTGaacataaagtttagcggggtaaactataatgaggaggg g" /listShort="ydgG, ydgH" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 608886 /Source="Nicolas_upshifts" /id="U439" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.528471528471528" /psig="0.97002997002997" /xcortree=2440 /SigmaFactorBS="gagtgctcgaaaataaaattTGTTGACAtatatagtttagag GAATAAACTAATTGACATTGaacataaagtttagcggggtaaactataatgaggaggg g" /listShort="ydgG, ydgH" /GFF_Attribute="listLong" CDS 608933..609391 /gene="ydgG" /locus_tag="BSU_05640" /old_locus_tag="BSU05640" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative transcriptional regulator (MarR family)" /protein_id="NP_388445.1" /db_xref="EnsemblGenomes-Gn:BSU05640" /db_xref="EnsemblGenomes-Tr:CAB12371" /db_xref="GOA:P96705" /db_xref="InterPro:IPR000835" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG12174" /db_xref="UniProtKB/Swiss-Prot:P96705" /translation="MNEQKLCQAINLFVEVLLEGTEFVHREINQDVFKHISREQADLL KILKVKGPTSPGSLAMYQNVHKSAISNRLKKLLEKGLVQWDDCPEKSDRRSKLINITP SGEHILEELDSAIFNALKPLIDDIDEEHLHSIIEIFTILKSKFKGGDSAE*" gene 608933..609391 /gene="ydgG" /locus_tag="BSU_05640" /old_locus_tag="BSU05640" CDS 609388..612045 /gene="ydgH" /locus_tag="BSU_05650" /old_locus_tag="BSU05650" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15941986; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative membrane component" /protein_id="NP_388446.1" /db_xref="EnsemblGenomes-Gn:BSU05650" /db_xref="EnsemblGenomes-Tr:CAB12372" /db_xref="GOA:P96706" /db_xref="InterPro:IPR000731" /db_xref="InterPro:IPR004869" /db_xref="SubtiList:BG12175" /db_xref="UniProtKB/Swiss-Prot:P96706" /translation="MRAIIKFKWAIAAIVLALTVVLSLFSPNLTELANQKGQAQLPAD AVSERANAILKQAGEDNNSISVVFTLDNAIKKETENQLRIIIDKIKKIDGVEEVTSPL SAEKEVKDQLMSKDKKTVLMPVTITGSDKKAEKIADEIYQIVPDDLTAYITGASLINQ DFAHSSEEGLKKTEVITVCLIIGLLLIVFRSVVTPFIPIVVVGFSYLISQSILGILVY NVDFPISTFTQTFLVAILFGIGTDYCILLLTRFREELANGHDKKEAALIAYRTGGKTL FISGFAVLIGFSALGFAKFAIFQSAVGVAVGVGILMIILYTLLPLFMVTLGEKLFWPS KKVLSHSDNKLWAFLGRHSVARPFLFIVITVVITLPFILTYDDQISFDSTAEISSDYK SIKALEAIKDGFGEGKAFPINVVVKGDKDLTTADTIPYLGNISKAIEKVDHVDSVMTI TQPTGKKIKDLYIDNQLGSVSDGLDKTVKGIADVQSGLTDIENGLNQMAGQTGSASNG GSGGSLGDAADGLGKINQQLQLVSKQISQTGNTAQTVQQLTAISGQLGQIQTGLEQAN QQLSGQQAQAGTLTESLKKLSEGVKSANEGLTKVSDGITASSDILEDMSKSPTVRDTG IFIPDQVMKDKDFKKSIDQYSFADGKGVQLSVVLDSNPYSEQAITTINQIKKAVANEV DGTPLENAQIVYGGVTSMNADLKELSTTDFSRTMVIMIIGLFIVLTILFRSMIMPIYM IASLLLTYYTSISITELIFVNGLGNAGVSWAVPFFSFVILIALGVDYSIFLLDRFKEE VHLGIEQGVVRSMSKMGSVIITAAIILAGTFAAMMPSGVNTLMQVASVIIIGLLLYGL VILPLFIPAIIATFGEGNWWPFGRKKGKE*" gene 609388..612045 /gene="ydgH" /locus_tag="BSU_05650" /old_locus_tag="BSU05650" downshifts 612166 /Source="Nicolas_upshifts" /id="D272" /incds=0 /nref=3 /ntot=27 /MaxReadThrough="0.245049999999999" /MaxDrop="4.45167" /score="13.780898" /energy="-13.9" /TU="NA" /idTUdmin="U439" /TUdmin=22 /isTUend="TRUE" CDS complement(612191..612820) /gene="ydgI" /locus_tag="BSU_05660" /old_locus_tag="BSU05660" /EC_number="1.-.-.-" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1c: Function from experimental evidences in the studied genus; PubMedId: 26415543; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="nitroreductase of unidentified specificity (reduces 5-(aziridin-1-yl)-2,4-dinitrobenzamide prodrug)" /protein_id="NP_388447.1" /db_xref="EnsemblGenomes-Gn:BSU05660" /db_xref="EnsemblGenomes-Tr:CAB12385" /db_xref="GOA:P96707" /db_xref="InterPro:IPR000415" /db_xref="InterPro:IPR029479" /db_xref="SubtiList:BG12176" /db_xref="UniProtKB/Swiss-Prot:P96707" /translation="MIKTNDFMEIMKGRRSIRNYDPAVKISKEEMTEILEEATTAPSS VNAQPWRFLVIDSPEGKEKLAPLASFNQTQVTTSSAVIAVFADMNNADYLEEIYSKAV ELGYMPQEVKDRQIAALTAHFEKLPAQVNRETILIDGGLVSMQLMLTARAHGYDTNPI GGYDKENIAETFGLDKERYVPVMLLSIGKAADEGYASYRLPIDTIAEWK*" gene complement(612191..612820) /gene="ydgI" /locus_tag="BSU_05660" /old_locus_tag="BSU05660" downshifts complement(612195) /Source="Nicolas_upshifts" /id="D273" /incds=0 /nref=21 /ntot=184 /MaxReadThrough="2.66406" /MaxDrop="6.06581" /score="21.7451043" /energy="-16.6" /TU="NA" /idTUdmin="U440" /TUdmin=3 /isTUend="TRUE" CDS complement(612836..613330) /gene="ydgJ" /locus_tag="BSU_05670" /old_locus_tag="BSU05670" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative transcriptional regulator (MarR family)" /protein_id="NP_388448.1" /db_xref="EnsemblGenomes-Gn:BSU05670" /db_xref="EnsemblGenomes-Tr:CAB12386" /db_xref="GOA:P96708" /db_xref="InterPro:IPR000835" /db_xref="InterPro:IPR001845" /db_xref="InterPro:IPR011991" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG12177" /db_xref="UniProtKB/Swiss-Prot:P96708" /translation="MTCQSLIYQLIVLTGKKGWVLASFCSEEAEILYQLQGVNKVIGV KFEACTGISQSRLELLTLLYHADEISQSDLQKKVNIDSAAVTRHLKQLESKGMVSRRR KPEDNRITLVRLTDQGRERIESSKKEKERFMKEMLANVSAEERRLLIDVLARMRNNIN NIEA*" gene complement(612836..613330) /gene="ydgJ" /locus_tag="BSU_05670" /old_locus_tag="BSU05670" promotor_-10 complement(613322..613341) /Source="Nicolas_upshift_promotors" /id="U440" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.633366633366633" /psig=1 /xcortree=1967 /SigmaFactorBS="ttatgcgctgggaggttgttcaaaagtgcaaatggCTTGCAa gatgaaatcaatcgTTGTATATTAATTGACGTGTcaatcattgatatatcaattaata g" /listShort="ydgJ, ydgI" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(613337) /Source="Nicolas_upshifts" /id="U440" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.633366633366633" /psig=1 /xcortree=1967 /SigmaFactorBS="ttatgcgctgggaggttgttcaaaagtgcaaatggCTTGCAa gatgaaatcaatcgTTGTATATTAATTGACGTGTcaatcattgatatatcaattaata g" /listShort="ydgJ, ydgI" /GFF_Attribute="listLong" promotor_-35 complement(613357..613362) /Source="Nicolas_upshift_promotors" /id="U440" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.633366633366633" /psig=1 /xcortree=1967 /SigmaFactorBS="ttatgcgctgggaggttgttcaaaagtgcaaatggCTTGCAa gatgaaatcaatcgTTGTATATTAATTGACGTGTcaatcattgatatatcaattaata g" /listShort="ydgJ, ydgI" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 613528..613530 /Source="Nicolas_upshift_promotors" /id="U441" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.786213786213786" /psig=1 /xcortree=2606 /SigmaFactorBS="ttcggaatatcactttgccggcccgtgctcaagcggCTTtca caggctgaaagtTATGATACAATATACAAATGtttcacagcttcaatccatagttgga g" /listShort="S199, ydgK" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 613546..613565 /Source="Nicolas_upshift_promotors" /id="U441" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.786213786213786" /psig=1 /xcortree=2606 /SigmaFactorBS="ttcggaatatcactttgccggcccgtgctcaagcggCTTtca caggctgaaagtTATGATACAATATACAAATGtttcacagcttcaatccatagttgga g" /listShort="S199, ydgK" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 613552..613640 /Source="Nicolas_S_feature" /locus_tag="new_613552_613640" /HighExp="H2O2, G180, G135, Diami, Paraq, Oxctl, G150, LBGexp, LPh, HPh" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S199" upshifts 613552 /Source="Nicolas_upshifts" /id="U441" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.786213786213786" /psig=1 /xcortree=2606 /SigmaFactorBS="ttcggaatatcactttgccggcccgtgctcaagcggCTTtca caggctgaaagtTATGATACAATATACAAATGtttcacagcttcaatccatagttgga g" /listShort="S199, ydgK" /GFF_Attribute="listLong" CDS 613641..614849 /gene="ydgK" /locus_tag="BSU_05680" /old_locus_tag="BSU05680" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative efflux transporter" /protein_id="NP_388449.1" /db_xref="EnsemblGenomes-Gn:BSU05680" /db_xref="EnsemblGenomes-Tr:CAB12387" /db_xref="GOA:P96709" /db_xref="InterPro:IPR004812" /db_xref="InterPro:IPR011701" /db_xref="InterPro:IPR020846" /db_xref="InterPro:IPR036259" /db_xref="SubtiList:BG12178" /db_xref="UniProtKB/Swiss-Prot:P96709" /translation="MLHNPTGKERLALAFLLGMLAILGPLNIDMYLPSFPEIAKDLSA SASLVQLSLTACLVGLTIGQLIVGPVSDAQGRRKPLLICIFLFALSSLFCALSPNITT LVAARFLQGFTASAGLVLSRAIVRDVFTGRELSKFFSLLMVITAVAPMVAPMTGGAIL LLPFATWHTIFHVLMIIGFLLVLLIALRLKETLPLEKRIPSSIGTSVKTMGSLLKDRS FMGYALTVGFIHGGSFAYVSGTPFVYQDIYGVSPQVFSILFGINGLAIISGSFIIGRF GGIIHEKSLLRIAVITAMIATAVLLTMTMIHGPLATLVISIFIYMITIGMVLTSTFTL AMEKQGHRAGSASALLGMLPLLLGSIVSPLVGINETTAVPMGAIMFVTAVIGSLAFFG LTKERVGQNS*" gene 613641..614849 /gene="ydgK" /locus_tag="BSU_05680" /old_locus_tag="BSU05680" downshifts 614828 /Source="Nicolas_upshifts" /id="D274" /incds=0 /nref=23 /ntot=112 /MaxReadThrough="0.507390000000001" /MaxDrop="3.27202" /score="25.806679" /energy="-7.5" /TU="NA" /idTUdmin="U441" /TUdmin=0 /isTUend="TRUE" CDS complement(614885..615622) /gene="ydhB" /locus_tag="BSU_05690" /old_locus_tag="BSU05690" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative integral inner membrane protein" /protein_id="NP_388450.2" /db_xref="EnsemblGenomes-Gn:BSU05690" /db_xref="EnsemblGenomes-Tr:CAB12388" /db_xref="GOA:O05493" /db_xref="InterPro:IPR002781" /db_xref="SubtiList:BG12179" /db_xref="UniProtKB/Swiss-Prot:O05493" /translation="MLIILVMFLLGIILGFIGAGGAGFVIALLTLLFHIPIHTALGTS LAGMAFTSLSGAYSHYREGNIQMKIGLIVGGFAAVGSFFGAKLTSFIPADLLHYLTAG MLFLSAILILIRLFILKEKAQVNQSTLSTYTRAVILGIAAGVLSGTFGIGSAPFIQIG LMIMLNLSIRHSVGTTMLVIIPLAVGGGIGYITEGFVDYVLLVKVLVGTMCGAYVGAK FTNLMPKVVLKSAIFLTPAIAGLLLLF*" gene complement(614885..615622) /gene="ydhB" /locus_tag="BSU_05690" /old_locus_tag="BSU05690" S_feature complement(615623..615761) /Source="Nicolas_S_feature" /locus_tag="new_615623_615761_c" /HighExp="T0.30H, T1.30H, T1.0H, T-0.40H, T2.0H, T0.0H, LBGstat, T2.30H, T-1.10H, T-1.40H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.108111" /TUshortSig="SigA" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S200" promotor_-10 complement(615749..615768) /Source="Nicolas_upshift_promotors" /id="U442" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.773226773226773" /psig="0.999000999001" /xcortree=1711 /SigmaFactorBS="atataacagatggtaatgggaagcaacaaactGCCTTGTCag atccctgaattTGAGGTACGATATGTTTGCTgaacgacggtcgacggactactggcaa c" /listShort="S200, ydhB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(615761) /Source="Nicolas_upshifts" /id="U442" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.773226773226773" /psig="0.999000999001" /xcortree=1711 /SigmaFactorBS="atataacagatggtaatgggaagcaacaaactGCCTTGTCag atccctgaattTGAGGTACGATATGTTTGCTgaacgacggtcgacggactactggcaa c" /listShort="S200, ydhB" /GFF_Attribute="listLong" promotor_-35 complement(615782..615789) /Source="Nicolas_upshift_promotors" /id="U442" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.773226773226773" /psig="0.999000999001" /xcortree=1711 /SigmaFactorBS="atataacagatggtaatgggaagcaacaaactGCCTTGTCag atccctgaattTGAGGTACGATATGTTTGCTgaacgacggtcgacggactactggcaa c" /listShort="S200, ydhB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 615793..615800 /Source="Nicolas_upshift_promotors" /id="U443" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.947052947052947" /psig="0.999000999001" /xcortree=1978 /SigmaFactorBS="atcgtacctcaaattcagggatctgacaaggcagtTTGTTGC TtcccattaccatcTGTTATATGATTTTGATGAAgaaaagcccttgaatatattcaaa a" /listShort="ydhC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 615814..615833 /Source="Nicolas_upshift_promotors" /id="U443" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.947052947052947" /psig="0.999000999001" /xcortree=1978 /SigmaFactorBS="atcgtacctcaaattcagggatctgacaaggcagtTTGTTGC TtcccattaccatcTGTTATATGATTTTGATGAAgaaaagcccttgaatatattcaaa a" /listShort="ydhC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 615818 /Source="Nicolas_upshifts" /id="U443" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.947052947052947" /psig="0.999000999001" /xcortree=1978 /SigmaFactorBS="atcgtacctcaaattcagggatctgacaaggcagtTTGTTGC TtcccattaccatcTGTTATATGATTTTGATGAAgaaaagcccttgaatatattcaaa a" /listShort="ydhC" /GFF_Attribute="listLong" CDS 615871..616545 /gene="ydhC" /locus_tag="BSU_05700" /old_locus_tag="BSU05700" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative transcriptional regulator (GntR family)" /protein_id="NP_388451.1" /db_xref="EnsemblGenomes-Gn:BSU05700" /db_xref="EnsemblGenomes-Tr:CAB12389" /db_xref="GOA:O05494" /db_xref="InterPro:IPR000485" /db_xref="InterPro:IPR000524" /db_xref="InterPro:IPR008920" /db_xref="InterPro:IPR011711" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG12180" /db_xref="UniProtKB/Swiss-Prot:O05494" /translation="MDDFKLDKPTPYYLQFYNQLKKMIFNGTFKPGERINETQLAKSF GVSRSPIREAMRLLEKDGLLKADDRNGFSITSLTAKDVDEIYKIRIPLEQLAVELVID EADEEELTILEKQLEETEKAIHNGTEDTEIIRLNQKFHELLVDFSHNRHLKNLLEHVN DLIHFCRILNYTGDHRAETILREHRRIFEEVKKKNKEAAKQHVLAHFNHDCEHLKHVL EEGKEN*" gene 615871..616545 /gene="ydhC" /locus_tag="BSU_05700" /old_locus_tag="BSU05700" promotor_-35 616604..616609 /Source="Nicolas_upshift_promotors" /id="U444" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.992007992007992" /psig="0.992007992007992" /xcortree=1131 /SigmaFactorBS="agcagaacccttggtatttttttatgtattcacCACATAtct aagaggccccgtTAATAAGATTTTATGATGGtttgactaacgaataatgggggttaaa t" /listShort="ydhD" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 616625..616643 /Source="Nicolas_upshift_promotors" /id="U444" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.992007992007992" /psig="0.992007992007992" /xcortree=1131 /SigmaFactorBS="agcagaacccttggtatttttttatgtattcacCACATAtct aagaggccccgtTAATAAGATTTTATGATGGtttgactaacgaataatgggggttaaa t" /listShort="ydhD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 616631 /Source="Nicolas_upshifts" /id="U444" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.992007992007992" /psig="0.992007992007992" /xcortree=1131 /SigmaFactorBS="agcagaacccttggtatttttttatgtattcacCACATAtct aagaggccccgtTAATAAGATTTTATGATGGtttgactaacgaataatgggggttaaa t" /listShort="ydhD" /GFF_Attribute="listLong" CDS 616672..617934 /gene="spoL" /locus_tag="BSU_05710" /old_locus_tag="BSU05710" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 11011148, 12177332; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="spore cortex lytic enzyme" /protein_id="NP_388452.2" /db_xref="EnsemblGenomes-Gn:BSU05710" /db_xref="EnsemblGenomes-Tr:CAB12390" /db_xref="GOA:O05495" /db_xref="InterPro:IPR001223" /db_xref="InterPro:IPR011583" /db_xref="InterPro:IPR017853" /db_xref="InterPro:IPR018392" /db_xref="InterPro:IPR036779" /db_xref="PDB:3CZ8" /db_xref="SubtiList:BG12181" /db_xref="UniProtKB/Swiss-Prot:O05495" /translation="MFIHIVGPGDSLFSIGRRYGASVDQIRGVNGLDETNIVPGQALL IPLYVYTVQPRDTLTAIAAKAFVPLERLRAANPGISPNALQAGAKITIPSISNYIAGT LSFYVLRNPDLDRELINDYAPYSSSISIFEYHIAPNGDIANQLNDAAAIETTWQRRVT PLATITNLTSGGFSTEIVHQVLNNPTARTNLVNNIYDLVSTRGYGGVTIDFEQVSAAD RDLFTGFLRQLRDRLQAGGYVLTIAVPAKTSDNIPWLRGYDYGGIGAVVNYMFIMAYD WHHAGSEPGPVAPITEIRRTIEFTIAQVPSRKIIIGVPLYGYDWIIPYQPGTVASAIS NQNAIERAMRYQAPIQYSAEYQSPFFRYSDQQGRTHEVWFEDVRSMSRKMQIVREYRL QAIGAWQLTLGFTPGPWLLRKFFTIRKV*" gene 616672..617934 /gene="spoL" /locus_tag="BSU_05710" /old_locus_tag="BSU05710" downshifts 617908 /Source="Nicolas_upshifts" /id="D275" /incds=0 /nref=33 /ntot=81 /MaxReadThrough="2.3134" /MaxDrop="5.20337" /score="15.7593331" /energy="-7.1" /TU="NA" /idTUdmin="U444" /TUdmin=0 /isTUend="TRUE" promotor_-35 618006..618013 /Source="Nicolas_upshift_promotors" /id="U445" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.612387612387612" /psig="0.999000999001" /xcortree=1616 /SigmaFactorBS="taagtccagagcagcagaatagttcattcatttgtACCTTGC AtgggttgtgttccCATTTTACGATTAGTAGTAGtctgatcaaacaaagagtcagaat a" /listShort="ydhE" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 618027..618046 /Source="Nicolas_upshift_promotors" /id="U445" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.612387612387612" /psig="0.999000999001" /xcortree=1616 /SigmaFactorBS="taagtccagagcagcagaatagttcattcatttgtACCTTGC AtgggttgtgttccCATTTTACGATTAGTAGTAGtctgatcaaacaaagagtcagaat a" /listShort="ydhE" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 618031 /Source="Nicolas_upshifts" /id="U445" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.612387612387612" /psig="0.999000999001" /xcortree=1616 /SigmaFactorBS="taagtccagagcagcagaatagttcattcatttgtACCTTGC AtgggttgtgttccCATTTTACGATTAGTAGTAGtctgatcaaacaaagagtcagaat a" /listShort="ydhE" /GFF_Attribute="listLong" CDS 618095..619282 /gene="ydhE" /locus_tag="BSU_05720" /old_locus_tag="BSU05720" /function="18.1: Enzymes of unknown specificity" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 20639339; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative glycosyltransferase" /protein_id="NP_388453.2" /db_xref="EnsemblGenomes-Gn:BSU05720" /db_xref="EnsemblGenomes-Tr:CAB12391" /db_xref="GOA:O05496" /db_xref="InterPro:IPR002213" /db_xref="InterPro:IPR006326" /db_xref="SubtiList:BG12182" /db_xref="UniProtKB/Swiss-Prot:O05496" /translation="MKTVLILNFPAEGHVNPTLGITKAFSDKGYDVHYISTEKYKKRL EAAGATVHLHRDLLRTTPIHVGSPNGILDFVKIHIKTSLDILQIVKDLSKSIQFDFVY YDKFGAGELVRDYLDIPGVSSSASFLFGEEHLKILPLHPESGAPLELDQECEDLLAKM KETYGVAPKNLVQFMNNKGELNVVYTSRYFQPESDRFGDECLFIGPSFPKRAEKTDFP IEQLKDEKVIYISMGTVLDHTEDFFNLCIDAFSGFNGKVVIAAGEKADLTKLKQAPEN FIIAPYVPQLEVLEQSDVFITHGGMNSVNEGIHFSVPLVVMPHDKDQPMVAQRLSELH AGYVISKDEVNAQILKQAVDEVLRNDQYTAGIKKINQSFKECMDMEEVMERIDELIRQ KNK*" gene 618095..619282 /gene="ydhE" /locus_tag="BSU_05720" /old_locus_tag="BSU05720" downshifts 619294 /Source="Nicolas_upshifts" /id="D276" /incds=0 /nref=17 /ntot=224 /MaxReadThrough="1.77672" /MaxDrop="5.25325" /score="-6.36206618" /energy="-12.6" /TU="NA" /idTUdmin="U445" /TUdmin=1 /isTUend="TRUE" CDS complement(619321..620031) /gene="ydhF" /locus_tag="BSU_05730" /old_locus_tag="BSU05730" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 10913081, 11557812; Product type lp: lipoprotein" /codon_start=1 /transl_table=11 /product="putative phosphate-starvation lipoprotein" /protein_id="NP_388454.1" /db_xref="EnsemblGenomes-Gn:BSU05730" /db_xref="EnsemblGenomes-Tr:CAB12392" /db_xref="InterPro:IPR029050" /db_xref="InterPro:IPR029051" /db_xref="SubtiList:BG12183" /db_xref="UniProtKB/Swiss-Prot:O05497" /translation="MRRILSILVFAIMLAGCSSNASTEKQHAGGEKTVKAEPQSTSSQ KDSTDDYQPNSQVTDDRTLHKVGQTFSDDKGKAVLKDIKQVNKTYKIGDVELTVKEMK LIHLRPDYSMIDYFHELTHDEEFDFVKVFVDIKNTSTKKVNVAPIALMKTNTGETFDW NKDIYLEELNGELEGGAEKSGNLGFIVNASSGHAHDKAADAEKKTKEIKWIEITTSDV FDHNHKKISDAQKIKIKF*" gene complement(619321..620031) /gene="ydhF" /locus_tag="BSU_05730" /old_locus_tag="BSU05730" downshifts complement(619347) /Source="Nicolas_upshifts" /id="D277" /incds=0 /nref=11 /ntot=36 /MaxReadThrough="4.05808" /MaxDrop="4.7318" /score="13.7192471" /energy="-12.6" /TU="NA" /idTUdmin="U446" /TUdmin=0 /isTUend="TRUE" CDS complement(620097..621485) /gene="phoB" /locus_tag="BSU_05740" /old_locus_tag="BSU05740" /EC_number="3.1.3.1" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:9335276, 10913081, 16030210, 16491025, 26382712, 27226549" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9335276, 10913081, 16030210, 16491025, 26382712, 27226549; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="alkaline phosphatase III (promiscuous, heptaprenylglyceryl phosphate is a substrate)" /protein_id="NP_388455.2" /db_xref="EnsemblGenomes-Gn:BSU05740" /db_xref="EnsemblGenomes-Tr:CAB12393" /db_xref="GOA:P19405" /db_xref="InterPro:IPR001952" /db_xref="InterPro:IPR017849" /db_xref="InterPro:IPR017850" /db_xref="InterPro:IPR018299" /db_xref="SubtiList:BG10697" /db_xref="UniProtKB/Swiss-Prot:P19405" /translation="MKKFPKKLLPIAVLSSIAFSSLASGSVPEASAQEKKKGNQDEIK NVIVLIGDGMGVSYTSAYRYLKDNKKTKVVEPTAFDQYLVGQQTTYPDDPEQNVTDSA AAATAMSAGIKTYNNAIAVDNDGSEAKTVLEAAKEKGKATGLVATSEITHATPASFGS HDHSRKNMNSIADDYFDEMVNGKHKIDVLLGGGKSNFDRKDRNLIKEFKKAGYSYVDD RKDMLKNKDSQVLGLFADGGLPKKIDRTKDIPSLKDMTNTAIKKLNKDKDGFFLMVEG SQIDWAGHDNDIVGAMSEMEDFEQAYKAAIDFAKKDKHTLVVATADHSTGGYSIGADG IYNWFSEPIKAAKRTPDFMAEKIADGADVEKTLKTYIDQKKLALTKAEIQSVEEAAKS KEVLDIDNAIENIFNKRSHTGWTTGGHTGEDVPVYAYGPSSETFAGQIDNTEIAKNVF KALQYNIKINDK*" gene complement(620097..621485) /gene="phoB" /locus_tag="BSU_05740" /old_locus_tag="BSU05740" promotor_-10 complement(621542..621559) /Source="Nicolas_upshift_promotors" /id="U446" /multdbtbs="SigA" /comp="M6" /sig="Sig-" /pcomp="0.982017982017982" /psig="0.011988011988012" /xcortree=9 /SigmaFactorBS="ggtgccagttcattattcttgtaaatccaaTCTTTAAAatcg atTAATACTAGCTTAACAGTttaaaaatataattgggttgtcattgagattcatctat a" /listShort="phoB, ydhF" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(621543) /Source="Nicolas_upshifts" /id="U446" /multdbtbs="SigA" /comp="M6" /sig="Sig-" /pcomp="0.982017982017982" /psig="0.011988011988012" /xcortree=9 /SigmaFactorBS="ggtgccagttcattattcttgtaaatccaaTCTTTAAAatcg atTAATACTAGCTTAACAGTttaaaaatataattgggttgtcattgagattcatctat a" /listShort="phoB, ydhF" /GFF_Attribute="listLong" S_feature complement(621545..621613) /Source="Nicolas_S_feature" /locus_tag="new_621545_621613_c" /HighExp="S6, S4, S5, S3, S7, LoTm, S8, T5.0H, B36, B60" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigEF" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S201" promotor_-35 complement(621566..621573) /Source="Nicolas_upshift_promotors" /id="U446" /multdbtbs="SigA" /comp="M6" /sig="Sig-" /pcomp="0.982017982017982" /psig="0.011988011988012" /xcortree=9 /SigmaFactorBS="ggtgccagttcattattcttgtaaatccaaTCTTTAAAatcg atTAATACTAGCTTAACAGTttaaaaatataattgggttgtcattgagattcatctat a" /listShort="phoB, ydhF" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(621603..621621) /Source="Nicolas_upshift_promotors" /id="U447" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1157 /SigmaFactorBS="tattcctccaatttatttctttagtactatcgctctttcCTT CTAaaacttctcataaaaGAATAACCATTATTTAAGGgtgccagttcattattcttgt a" /listShort="S201, phoB, ydhF" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(621621) /Source="Nicolas_upshifts" /id="U447" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1157 /SigmaFactorBS="tattcctccaatttatttctttagtactatcgctctttcCTT CTAaaacttctcataaaaGAATAACCATTATTTAAGGgtgccagttcattattcttgt a" /listShort="S201, phoB, ydhF" /GFF_Attribute="listLong" promotor_-35 complement(621637..621642) /Source="Nicolas_upshift_promotors" /id="U447" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1157 /SigmaFactorBS="tattcctccaatttatttctttagtactatcgctctttcCTT CTAaaacttctcataaaaGAATAACCATTATTTAAGGgtgccagttcattattcttgt a" /listShort="S201, phoB, ydhF" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 621690..621697 /Source="Nicolas_upshift_promotors" /id="U448" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.642357642357642" /psig="0.997002997002997" /xcortree=1887 /SigmaFactorBS="tagtactaaagaaataaattggaggaatagatactggCCGTG GATaggcggactgaaaTCTGCTATAGTCGCATAGAAgcaacccgcttacatcttgaac a" /listShort="S202, ydhG" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 621711..621730 /Source="Nicolas_upshift_promotors" /id="U448" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.642357642357642" /psig="0.997002997002997" /xcortree=1887 /SigmaFactorBS="tagtactaaagaaataaattggaggaatagatactggCCGTG GATaggcggactgaaaTCTGCTATAGTCGCATAGAAgcaacccgcttacatcttgaac a" /listShort="S202, ydhG" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 621713..621846 /Source="Nicolas_S_feature" /locus_tag="new_621713_621846" /HighExp="Diami, dia15, H2O2, Paraq, Oxctl, HPh, G180, G135, LPh, Cold" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.997" /TUlongSig="NA" /TUlongPSig="NA" /label="S202" upshifts 621713 /Source="Nicolas_upshifts" /id="U448" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.642357642357642" /psig="0.997002997002997" /xcortree=1887 /SigmaFactorBS="tagtactaaagaaataaattggaggaatagatactggCCGTG GATaggcggactgaaaTCTGCTATAGTCGCATAGAAgcaacccgcttacatcttgaac a" /listShort="S202, ydhG" /GFF_Attribute="listLong" CDS 621847..622218 /gene="fra" /locus_tag="BSU_05750" /old_locus_tag="BSU05750" /function="16.10: Respire" /experiment="publication(s) with functional evidences, PMID:20087498, 21744456, 25826316" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 20087498, 21744456, 25826316; Product type f: factor" /codon_start=1 /transl_table=11 /product="frataxin; iron/sulfur chaperone" /protein_id="NP_388456.1" /db_xref="EnsemblGenomes-Gn:BSU05750" /db_xref="EnsemblGenomes-Tr:CAB12394" /db_xref="GOA:Q797E6" /db_xref="InterPro:IPR014922" /db_xref="PDB:2OC6" /db_xref="SubtiList:BG12184" /db_xref="UniProtKB/Swiss-Prot:Q797E6" /translation="MDVFSEYLAGIADPFHRERTEEVLTWIKNKYPNLHTEIKWNQPM FTDHGTFIIGFSVSKKHLAVAPEKVTIAHVEDDIVKAGYDYTEQLIRIPWNGPVDYTL LEKMIEFNILDKADCSTFWRK*" gene 621847..622218 /gene="fra" /locus_tag="BSU_05750" /old_locus_tag="BSU05750" downshifts 622197 /Source="Nicolas_upshifts" /id="D278" /incds=0 /nref=9 /ntot=150 /MaxReadThrough="2.88587" /MaxDrop="3.59127" /score="28.8500849" /energy="-8.1" /TU="NA" /idTUdmin="U448" /TUdmin=0 /isTUend="TRUE" downshifts complement(622292) /Source="Nicolas_upshifts" /id="D279" /incds=0 /nref=9 /ntot=187 /MaxReadThrough="1.63268" /MaxDrop="2.98181" /score="0.51805655" /energy="-13" /TU="NA" /idTUdmin="U450" /TUdmin=2 /isTUend="TRUE" CDS complement(622293..622790) /gene="ydhH" /locus_tag="BSU_05760" /old_locus_tag="BSU05760" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_388457.1" /db_xref="EnsemblGenomes-Gn:BSU05760" /db_xref="EnsemblGenomes-Tr:CAB12395" /db_xref="GOA:O05500" /db_xref="InterPro:IPR032545" /db_xref="SubtiList:BG12185" /db_xref="UniProtKB/Swiss-Prot:O05500" /translation="MSSHYKYPLIFTAFLLIAFCLIFFSYHLIHHVRLEYPNWQGESK DQNWEAVFTKNEDAPNEYSGKLYWIGDTIEIDNTYLESLIVKKDDEVLLSSDTEIPMH DYAGGTFSDGSAKEKSVSFLERLDEHELEGHDITIEVKWKQGNHYSASQLTLNEKTLF DEKQQ*" gene complement(622293..622790) /gene="ydhH" /locus_tag="BSU_05760" /old_locus_tag="BSU05760" CDS complement(622808..623290) /gene="ydhI" /locus_tag="BSU_05770" /old_locus_tag="BSU05770" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative acetyltransferase" /protein_id="NP_388458.1" /db_xref="EnsemblGenomes-Gn:BSU05770" /db_xref="EnsemblGenomes-Tr:CAB12396" /db_xref="GOA:O05501" /db_xref="InterPro:IPR000182" /db_xref="InterPro:IPR016181" /db_xref="SubtiList:BG12186" /db_xref="UniProtKB/Swiss-Prot:O05501" /translation="MMIIIPNNEIAKHMLTDFFAKHWGTPEMAISSGIFRCDELDGFA AVNESGEIIGCITYTIDGKDCEIISLDSMIENKGIGTALLQQVEEKAKHAHCQRIKLI TTNDNVNAIAFYQKRGYQFAAVFPNAVEKARRLKPEIPEVAENGILIRDEILFSKVID *" gene complement(622808..623290) /gene="ydhI" /locus_tag="BSU_05770" /old_locus_tag="BSU05770" promotor_-35 622963..622970 /Source="Nicolas_upshift_promotors" /id="U449" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.767232767232767" /psig=1 /xcortree=2430 /SigmaFactorBS="gaattgatagcctctcttttgataaaacgctatcgCATTTAC AttatcattcgttgTGATAAGCTTTATTCGTTGAcaatgtgcatgtttagccttctct t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 622984..623003 /Source="Nicolas_upshift_promotors" /id="U449" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.767232767232767" /psig=1 /xcortree=2430 /SigmaFactorBS="gaattgatagcctctcttttgataaaacgctatcgCATTTAC AttatcattcgttgTGATAAGCTTTATTCGTTGAcaatgtgcatgtttagccttctct t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 622988 /Source="Nicolas_upshifts" /id="U449" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.767232767232767" /psig=1 /xcortree=2430 /SigmaFactorBS="gaattgatagcctctcttttgataaaacgctatcgCATTTAC AttatcattcgttgTGATAAGCTTTATTCGTTGAcaatgtgcatgtttagccttctct t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 complement(623319..623338) /Source="Nicolas_upshift_promotors" /id="U450" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.619380619380619" /psig="0.994005994005994" /xcortree=2264 /SigmaFactorBS="atatcgctgatttccatgccgtcacctcaacatCTATttttt ttgttatatATTGTTTATATTGATAGTACatatgcaatctttcaatagaggagtgtta t" /listShort="ydhI, ydhH" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(623329) /Source="Nicolas_upshifts" /id="U450" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.619380619380619" /psig="0.994005994005994" /xcortree=2264 /SigmaFactorBS="atatcgctgatttccatgccgtcacctcaacatCTATttttt ttgttatatATTGTTTATATTGATAGTACatatgcaatctttcaatagaggagtgtta t" /listShort="ydhI, ydhH" /GFF_Attribute="listLong" promotor_-35 complement(623353..623356) /Source="Nicolas_upshift_promotors" /id="U450" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.619380619380619" /psig="0.994005994005994" /xcortree=2264 /SigmaFactorBS="atatcgctgatttccatgccgtcacctcaacatCTATttttt ttgttatatATTGTTTATATTGATAGTACatatgcaatctttcaatagaggagtgtta t" /listShort="ydhI, ydhH" /GFF_Attribute="listLong" /label="promotor_-35" CDS 623373..624350 /gene="ydhJ" /locus_tag="BSU_05780" /old_locus_tag="BSU05780" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative metal-dependent phosphohydrolase" /protein_id="NP_388459.1" /db_xref="EnsemblGenomes-Gn:BSU05780" /db_xref="EnsemblGenomes-Tr:CAB12397" /db_xref="GOA:O05502" /db_xref="InterPro:IPR003607" /db_xref="InterPro:IPR006674" /db_xref="SubtiList:BG12187" /db_xref="UniProtKB/Swiss-Prot:O05502" /translation="MEISDIIYGQHHIDGVLEELIKSAPVQRLKGIYQGGASFLVNRK WNVTRYEHSIGVMLLIKKLGGTIEEQIAGLLHDVSHTAFSHVVDVVFENQAEDYHENI FQQVIVHSEIPDILQKHGYHTEELLSDDSRWTLLEQPAPELCADRTDYTLRDMYRYGH INLHEAQTFLDHLIVRNGRMFPDSIEAAEWFVSVYYKEVIDFFLNPVNVYGYEYLARA LKAALRHDVISAEDLLKTDQEVLNILRASKNEEVLSLLTSIHPGIQVIEDDIQYDFHQ KKKMRLIDPSIFLDDKWIKSSGVSEKVRKMGEAAYQKAKKGVYIKILKQ*" gene 623373..624350 /gene="ydhJ" /locus_tag="BSU_05780" /old_locus_tag="BSU05780" downshifts 624330 /Source="Nicolas_upshifts" /id="D280" /incds=0 /nref=2 /ntot=92 /MaxReadThrough="2.31799" /MaxDrop="3.19063" /score="28.8500849" /energy="-8.1" /TU="NA" /idTUdmin="U451" /TUdmin="-770" /isTUend="FALSE" promotor_-35 624377..624383 /Source="Nicolas_upshift_promotors" /id="U451" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=176 /SigmaFactorBS="agtaattgccgcctgacagcggctttttttaTGTTTGGcttt gcaaacaaagGGGAATAGGACAAACTGCGggaacgctttatgagaatatcagcgtatt t" /listShort="ydhK" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 624398..624416 /Source="Nicolas_upshift_promotors" /id="U451" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=176 /SigmaFactorBS="agtaattgccgcctgacagcggctttttttaTGTTTGGcttt gcaaacaaagGGGAATAGGACAAACTGCGggaacgctttatgagaatatcagcgtatt t" /listShort="ydhK" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 624406 /Source="Nicolas_upshifts" /id="U451" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=176 /SigmaFactorBS="agtaattgccgcctgacagcggctttttttaTGTTTGGcttt gcaaacaaagGGGAATAGGACAAACTGCGggaacgctttatgagaatatcagcgtatt t" /listShort="ydhK" /GFF_Attribute="listLong" promotor_-35 624442..624449 /Source="Nicolas_upshift_promotors" /id="U452" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.434565434565435" /psig="0.98001998001998" /xcortree=1765 /SigmaFactorBS="ataggacaaactgcgggaacgctttatgagaatatcagcgTA TTTACAtaccgttcgggggTATAGTATTATCGAGAGGGCatgttttcattgtctgcgg g" /listShort="ydhK" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 624462 /Source="Nicolas_upshifts" /id="U452" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.434565434565435" /psig="0.98001998001998" /xcortree=1765 /SigmaFactorBS="ataggacaaactgcgggaacgctttatgagaatatcagcgTA TTTACAtaccgttcgggggTATAGTATTATCGAGAGGGCatgttttcattgtctgcgg g" /listShort="ydhK" /GFF_Attribute="listLong" promotor_-10 624463..624482 /Source="Nicolas_upshift_promotors" /id="U452" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.434565434565435" /psig="0.98001998001998" /xcortree=1765 /SigmaFactorBS="ataggacaaactgcgggaacgctttatgagaatatcagcgTA TTTACAtaccgttcgggggTATAGTATTATCGAGAGGGCatgttttcattgtctgcgg g" /listShort="ydhK" /GFF_Attribute="listLong" /label="promotor_-10" CDS 624492..625109 /gene="ydhK" /locus_tag="BSU_05790" /old_locus_tag="BSU05790" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="NP_388460.1" /db_xref="EnsemblGenomes-Gn:BSU05790" /db_xref="EnsemblGenomes-Tr:CAB12398" /db_xref="InterPro:IPR011438" /db_xref="PDB:2KY9" /db_xref="PDB:4FIB" /db_xref="PDB:4MDW" /db_xref="SubtiList:BG12188" /db_xref="UniProtKB/Swiss-Prot:O05503" /translation="MSAGKSYRKKMKQRRMNMKISKYALGILMLSLVFVLSACGNNNS TKESTHDNHSDSSTHEEMDHSGSADVPEGLQESKNPKYKVGSQVIINTSHMKGMKGAE ATVTGAYDTTAYVVSYTPTNGGQRVDHHKWVIQEEIKDAGDKTLQPGDQVILEASHMK GMKGATAEIDSAEKTTVYMVDYTSTTSGEKVKNHKWVTEDELSAK*" gene 624492..625109 /gene="ydhK" /locus_tag="BSU_05790" /old_locus_tag="BSU05790" downshifts 625096 /Source="Nicolas_upshifts" /id="D281" /incds=0 /nref=62 /ntot=212 /MaxReadThrough="1.07295" /MaxDrop="7.27889" /score="30.3859931" /energy="-11.4" /TU="U452" /idTUdmin="U451" /TUdmin="-4" /isTUend="TRUE" CDS complement(625125..626291) /gene="pbuE" /locus_tag="BSU_05800" /old_locus_tag="BSU05800" /function="16.8: Protect" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:12923093, 15849754, 16850406, 17935948, 25573585" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12923093, 15849754, 16850406, 17935948, 25573585; Product type t : transporter" /codon_start=1 /transl_table=11 /product="hypoxanthine efflux transporter" /protein_id="NP_388461.2" /db_xref="EnsemblGenomes-Gn:BSU05800" /db_xref="EnsemblGenomes-Tr:CAB12399" /db_xref="GOA:Q797E3" /db_xref="InterPro:IPR011701" /db_xref="InterPro:IPR020846" /db_xref="InterPro:IPR036259" /db_xref="SubtiList:BG12189" /db_xref="UniProtKB/Swiss-Prot:Q797E3" /translation="MNFKVFLLAASTIAVGLVELIVGGILPQIANDLDISIVSAGQLI SVFALGYAVSGPLLLALTAKIERKRLYLIALFVFFLSNLVAYFSPNFATLMVSRVLAA MSTGLIVVLSLTIAPKIVAPEYRARAIGIIFMGFSSAIALGVPLGILISDSFGWRILF LGIGLLALISMLIISIFFERIPAEKMIPFREQLKTIGNLKIASSHLVTMFTLAGHYTL YAYFAPFLEETLHLSSFWVSICYFLFGISAVCGGPFGGALSDRLGSFKSILLVTGSFA IIMFLLPLSTSSMIFFLPVMVIWGLLSWSLAPAQQSYLIEIAPDSSDIQQSFNTSALQ VGIALGSAIGGVVLDQTGTVVSTAWCGGSIVIIAVLFAFISLTRPVQTAKKSSL*" gene complement(625125..626291) /gene="pbuE" /locus_tag="BSU_05800" /old_locus_tag="BSU05800" downshifts complement(625154) /Source="Nicolas_upshifts" /id="D282" /incds=0 /nref=40 /ntot=58 /MaxReadThrough="2.22188" /MaxDrop="4.89202" /score="36.362851" /energy="-12.4" /TU="NA" /idTUdmin="U453" /TUdmin=0 /isTUend="TRUE" misc_RNA complement(626346..626446) /gene="aswA" /locus_tag="BSU_misc_RNA_8" /product="adenine riboswitch" /experiment="publication(s) with functional evidences, PMID:14718920, 16201765, 19603494, 20022916, 21283784, 23087247, 25573585" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 14718920, 16201765, 19603494, 20022916, 21283784, 23087247, 25573585; Product type n: RNA" gene complement(626346..626446) /gene="aswA" /locus_tag="BSU_misc_RNA_8" downshifts complement(626387) /Source="Nicolas_upshifts" /id="D283" /incds=0 /nref=38 /ntot=127 /MaxReadThrough="5.85661" /MaxDrop="6.06248" /score="33.0784595" /energy="-19.4" /TU="U453" /idTUdmin="U453" /TUdmin="-1233" /isTUend="FALSE" promotor_-10 complement(626456..626475) /Source="Nicolas_upshift_promotors" /id="U453" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.95104895104895" /psig=1 /xcortree=2453 /SigmaFactorBS="tatttttttccggttcaccgttttataaatttttcTATGGaa gattcattcataaTGTGGTACACTCATCAACGGaaacgaatcaattaaatagctatta t" /listShort="NA, pbuE" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(626470) /Source="Nicolas_upshifts" /id="U453" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.95104895104895" /psig=1 /xcortree=2453 /SigmaFactorBS="tatttttttccggttcaccgttttataaatttttcTATGGaa gattcattcataaTGTGGTACACTCATCAACGGaaacgaatcaattaaatagctatta t" /listShort="NA, pbuE" /GFF_Attribute="listLong" promotor_-35 complement(626491..626495) /Source="Nicolas_upshift_promotors" /id="U453" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.95104895104895" /psig=1 /xcortree=2453 /SigmaFactorBS="tatttttttccggttcaccgttttataaatttttcTATGGaa gattcattcataaTGTGGTACACTCATCAACGGaaacgaatcaattaaatagctatta t" /listShort="NA, pbuE" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 626554..626561 /Source="Nicolas_upshift_promotors" /id="U454" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.85914085914086" /psig="0.999000999001" /xcortree=1575 /SigmaFactorBS="aaaaaaatatgattatatttattttataaaagTATAGACAtt taaaattaaatGACTATAATAATCAATGTAAgcgttttaataacaggggggatagcag t" /listShort="gmuB, gmuA, gmuC, gmuD, S203, gmuR, gmuE, gmuF, gmuG" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 626575..626594 /Source="Nicolas_upshift_promotors" /id="U454" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.85914085914086" /psig="0.999000999001" /xcortree=1575 /SigmaFactorBS="aaaaaaatatgattatatttattttataaaagTATAGACAtt taaaattaaatGACTATAATAATCAATGTAAgcgttttaataacaggggggatagcag t" /listShort="gmuB, gmuA, gmuC, gmuD, S203, gmuR, gmuE, gmuF, gmuG" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 626582 /Source="Nicolas_upshifts" /id="U454" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.85914085914086" /psig="0.999000999001" /xcortree=1575 /SigmaFactorBS="aaaaaaatatgattatatttattttataaaagTATAGACAtt taaaattaaatGACTATAATAATCAATGTAAgcgttttaataacaggggggatagcag t" /listShort="gmuB, gmuA, gmuC, gmuD, S203, gmuR, gmuE, gmuF, gmuG" /GFF_Attribute="listLong" CDS 626622..626933 /gene="gmuB" /locus_tag="BSU_05810" /old_locus_tag="BSU05810" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 18177310; Product type t : transporter" /codon_start=1 /transl_table=11 /product="oligo-alpha-mannoside phosphotransferase system enzyme IIB" /protein_id="NP_388462.1" /db_xref="EnsemblGenomes-Gn:BSU05810" /db_xref="EnsemblGenomes-Tr:CAB12400" /db_xref="GOA:O05505" /db_xref="InterPro:IPR003501" /db_xref="InterPro:IPR013012" /db_xref="InterPro:IPR036095" /db_xref="SubtiList:BG12190" /db_xref="UniProtKB/Swiss-Prot:O05505" /translation="MKKILLACSSGMSTSLLVTKMKEYAQSIGEEAEIWAVGQDKAKE DMRKADAVLIGPQMSFLKSELQKEADQYNIQVEVIDMMAYGMADGKKAYEQALSLMVN Q*" gene 626622..626933 /gene="gmuB" /locus_tag="BSU_05810" /old_locus_tag="BSU05810" CDS 626933..627265 /gene="gmuA" /locus_tag="BSU_05820" /old_locus_tag="BSU05820" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; Product type t: transporter" /codon_start=1 /transl_table=11 /product="oligo-alpha-mannoside phosphotransferase system enzyme IIA" /protein_id="NP_388463.2" /db_xref="EnsemblGenomes-Gn:BSU05820" /db_xref="EnsemblGenomes-Tr:CAB12401" /db_xref="GOA:O05506" /db_xref="InterPro:IPR003188" /db_xref="InterPro:IPR036542" /db_xref="SubtiList:BG12191" /db_xref="UniProtKB/Swiss-Prot:O05506" /translation="MEQMKITNLTDEQISFQLILHSGNARSCIIQSLRAYKEGKKDEA DALIAKAEQDLSAAHDIHFQMIQKESGGEATAFSLLLMHAEDHLMSTLSMKELVKEML DLFKTKNI*" gene 626933..627265 /gene="gmuA" /locus_tag="BSU_05820" /old_locus_tag="BSU05820" CDS 627284..628612 /gene="gmuC" /locus_tag="BSU_05830" /old_locus_tag="BSU05830" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 15849754, 16850406, 18177310; Product type t: transporter" /codon_start=1 /transl_table=11 /product="oligo-alpha-mannoside phosphotransferase system enzyme IIC" /protein_id="NP_388464.1" /db_xref="EnsemblGenomes-Gn:BSU05830" /db_xref="EnsemblGenomes-Tr:CAB12402" /db_xref="GOA:O05507" /db_xref="InterPro:IPR003352" /db_xref="InterPro:IPR004501" /db_xref="InterPro:IPR004796" /db_xref="SubtiList:BG12192" /db_xref="UniProtKB/Swiss-Prot:O05507" /translation="MFEKISQFLVPIAGRLNNNRYLQVLRDAFMLAFPLTIFGSIFVV LTNLPFLNKIMNASMLTSFQSHFGIASTATMGIMSVFVVFGIGYYLSKSYQVEAVFGG AIALVSFLLLTPFIIQPETGDAITGVIPVDRLGAKGMFLGMITAFLSGEIYRRIVQKN LTIKMPAGVPPAVAKSFAALIPAFITLTVFLLINVMVTLFFKTNMHDVIYHAIQAPLV GLGSGIIPTLIAVFFIQILWFFGLHGQIIINSVMDPIWNTLQVENLSAYTAGKEIPHI ISKPFMEIYTVGMGGTGMTLAIVFTILIFMKSRQMKQVSKLGLAPGIFNVNEPIIFGL PIVMNPIIIVPWVLAPMVVTLVTYLAMSAGLVPPPTGVTVPWTVPLFINGIMATNSIM GGVMQLINLLIVFVIWFPFLKAMDKLNLAKEKEQAVQETAAQQNDNSIKM*" gene 627284..628612 /gene="gmuC" /locus_tag="BSU_05830" /old_locus_tag="BSU05830" CDS 628630..630027 /gene="gmuD" /locus_tag="BSU_05840" /old_locus_tag="BSU05840" /EC_number="3.2.1.86" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:14652714, 15139916, 18177310" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 14652714, 15139916, 18177310; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="mannoside-phospho-beta-d-glucosidase" /protein_id="NP_388465.1" /db_xref="EnsemblGenomes-Gn:BSU05840" /db_xref="EnsemblGenomes-Tr:CAB12403" /db_xref="GOA:O05508" /db_xref="InterPro:IPR001360" /db_xref="InterPro:IPR017853" /db_xref="InterPro:IPR018120" /db_xref="SubtiList:BG12193" /db_xref="UniProtKB/Swiss-Prot:O05508" /translation="MAHTEQYRFPKDFWWGSSASATQMEGAADRDGKGQNIWDYWFEK EPHRFFDHVGPADTSQFYDNYKEDIRLMKELGHNSFRMSISWSRLIPNGTGEINDKAA DFYNNVIDELIANGIEPFVNLFHFDMPMALQKIGGWVNRETVDAYENYARTCFRLFGG RVKKWFTHNEPIVPVEGGYLYDFHYPNKVDFKEAVQVGFHTMLSSARAIQAYREMKQD GKIGIILNLTPSYPRSSHPADVKAGEIADAFFNRSFLDPSVKGEFPKELVDILKHEGF MPDYNAEDLDIIKKNTVDLLGVNYYQPRRVKAKEHLPNPDAPFLPDRYFDPYVMPGRK MNPHRGWEIYEKGVYDILINLKENYGNIECFISENGMGVEGEERFRDEQGIIQDDYRI EFIKEHLKWIHRAIQEGSNVKGYHLWTFMDNWSWTNAYKNRYGFVSVNLEKDGERTVK KSGKWFKEVAEHSGF*" gene 628630..630027 /gene="gmuD" /locus_tag="BSU_05840" /old_locus_tag="BSU05840" S_feature 630028..630114 /Source="Nicolas_S_feature" /locus_tag="new_630028_630114" /HighExp="G150, T0.30H, T1.0H, M40t90, T1.30H, Mt0, M0t90, Lbexp, dia0, T2.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S203" promotor_-35 630092..630099 /Source="Nicolas_upshift_promotors" /id="U455" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.74025974025974" /psig="0.997002997002997" /xcortree=640 /SigmaFactorBS="aatcatcataacgaatagagatgacgaaaatccgcaACATTG ATgaaatagggaaaaGAACTTATGATATCCGTAAAagcttatgtgatatcaaacagct g" /listShort="gmuR, gmuE, gmuF, gmuG" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 630113..630132 /Source="Nicolas_upshift_promotors" /id="U455" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.74025974025974" /psig="0.997002997002997" /xcortree=640 /SigmaFactorBS="aatcatcataacgaatagagatgacgaaaatccgcaACATTG ATgaaatagggaaaaGAACTTATGATATCCGTAAAagcttatgtgatatcaaacagct g" /listShort="gmuR, gmuE, gmuF, gmuG" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 630116 /Source="Nicolas_upshifts" /id="U455" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.74025974025974" /psig="0.997002997002997" /xcortree=640 /SigmaFactorBS="aatcatcataacgaatagagatgacgaaaatccgcaACATTG ATgaaatagggaaaaGAACTTATGATATCCGTAAAagcttatgtgatatcaaacagct g" /listShort="gmuR, gmuE, gmuF, gmuG" /GFF_Attribute="listLong" CDS 630170..630883 /gene="gmuR" /locus_tag="BSU_05850" /old_locus_tag="BSU05850" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:18177310" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 18177310; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator (GntR family)" /protein_id="NP_388466.1" /db_xref="EnsemblGenomes-Gn:BSU05850" /db_xref="EnsemblGenomes-Tr:CAB12404" /db_xref="GOA:O05509" /db_xref="InterPro:IPR000524" /db_xref="InterPro:IPR011663" /db_xref="InterPro:IPR028978" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG12194" /db_xref="UniProtKB/Swiss-Prot:O05509" /translation="MNKYEIIANEMRNRIKNNVYPIDQPIPDEVSLAKEFNSSRMTMK RALDNLVAEGLLFRKRGHGTFIIQSAIQDDHVHVVSNEILGLTNLLKDKKIKSKVIQF EVQFPTEEVAAHLSIDQKTPVYYVVRLRIVEGEPYVLEKTYMPTHLIPGINDDVLHDS IYNHITNVLQLKIAGTHRKIRACKSDHIDQQHLGCKQDDPILEVEHVGFLDTGIPFEY SFSRHRHDKFVVTSVNIRR*" gene 630170..630883 /gene="gmuR" /locus_tag="BSU_05850" /old_locus_tag="BSU05850" CDS 630912..631811 /gene="gmuE" /locus_tag="BSU_05860" /old_locus_tag="BSU05860" /EC_number="2.7.1.4" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:15018644, 18177310, 21185308" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15018644, 18177310, 21185308; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="ROK fructokinase; glucomannan utilization protein E" /protein_id="NP_388467.1" /db_xref="EnsemblGenomes-Gn:BSU05860" /db_xref="EnsemblGenomes-Tr:CAB12405" /db_xref="GOA:O05510" /db_xref="InterPro:IPR000600" /db_xref="PDB:1XC3" /db_xref="PDB:3LM9" /db_xref="PDB:3OHR" /db_xref="SubtiList:BG12195" /db_xref="UniProtKB/Swiss-Prot:O05510" /translation="MLGGIEAGGTKFVCAVGREDGTIIDRIEFPTKMPDETIEKVIQY FSQFSLQAIGIGSFGPVDNDKTSQTYGTITATPKAGWRHYPFLQTVKNEMKIPVGFST DVNAAALGEFLFGEAKGLDSCLYITIGTGIGAGAIVEGRLLQGLSHPEMGHIYIRRHP DDVYQGKCPYHGDCFEGLASGPAIEARWGKKAADLSDIAQVWELEGYYIAQALAQYIL ILAPKKIILGGGVMQQKQVFSYIYQYVPKIMNSYLDFSELSDDISDYIVPPRLGSNAG IIGTLVLAHQALQAEAASGEVRS*" gene 630912..631811 /gene="gmuE" /locus_tag="BSU_05860" /old_locus_tag="BSU05860" CDS 631808..632755 /gene="gmuF" /locus_tag="BSU_05870" /old_locus_tag="BSU05870" /EC_number="5.3.1.8" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2b: Function from indirect experimental evidences (e.g. phenotypes); PubMedId: 10704478, 18177310, 3017192; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="phosphohexomutase; cupin family" /protein_id="NP_388468.1" /db_xref="EnsemblGenomes-Gn:BSU05870" /db_xref="EnsemblGenomes-Tr:CAB12406" /db_xref="GOA:O05511" /db_xref="InterPro:IPR001250" /db_xref="InterPro:IPR011051" /db_xref="InterPro:IPR014628" /db_xref="InterPro:IPR014710" /db_xref="SubtiList:BG12196" /db_xref="UniProtKB/Swiss-Prot:O05511" /translation="MTHPLFLEPVFKERLWGGTKLRDAFGYAIPSQKTGECWAVSAHA HGSSSVKNGPLAGKTLDQVWKDHPEIFGFPDGKVFPLLVKLLDANMDLSVQVHPDDDY AKLHENGDLGKTECWYIIDCKDDAELILGHHASTKEEFKQRIESGDWNGLLRRIKIKP GDFFYVPSGTLHALCKGTLVLEIQQNSDTTYRVYDYDRCNDQGQKRTLHIEKAMEVIT IPHIDKVHTPEVKEVGNAEIIVYVQSDYFSVYKWKISGRAAFPSYQTYLLGSVLSGSG RIINNGIQYECNAGSHFILPAHFGEFTIEGTCEFMISHP*" gene 631808..632755 /gene="gmuF" /locus_tag="BSU_05870" /old_locus_tag="BSU05870" CDS 632774..633862 /gene="gmuG" /locus_tag="BSU_05880" /old_locus_tag="BSU05880" /EC_number="3.2.1.78" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:2694961, 7727534, 18177310, 28101462, 25355936" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 2694961, 7727534, 18177310, 28101462, 25355936; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="exported mannan endo-1,4-beta-mannosidase" /protein_id="NP_388469.2" /db_xref="EnsemblGenomes-Gn:BSU05880" /db_xref="EnsemblGenomes-Tr:CAB12407" /db_xref="GOA:O05512" /db_xref="InterPro:IPR000805" /db_xref="InterPro:IPR016714" /db_xref="InterPro:IPR017853" /db_xref="InterPro:IPR022790" /db_xref="PDB:2WHK" /db_xref="PDB:3CBW" /db_xref="SubtiList:BG12197" /db_xref="UniProtKB/Swiss-Prot:O05512" /translation="MFKKHTISLLIIFLLASAVLAKPIEAHTVSPVNPNAQQTTKTVM NWLAHLPNRTENRVLSGAFGGYSHDTFSMAEADRIRSATGQSPAIYGCDYARGWLETA NIEDSIDVSCNGDLMSYWKNGGIPQISLHLANPAFQSGHFKTPITNDQYKKILDSSTV EGKRLNAMLSKIADGLQELENQGVPVLFRPLHEMNGEWFWWGLTSYNQKDNERISLYK QLYKKIYHYMTDTRGLDHLIWVYSPDANRDFKTDFYPGASYVDIVGLDAYFQDAYSIN GYDQLTALNKPFAFTEVGPQTANGSFDYSLFINAIKQKYPKTIYFLAWNDEWSAAVNK GASALYHDSWTLNKGEIWNGDSLTPIVE*" gene 632774..633862 /gene="gmuG" /locus_tag="BSU_05880" /old_locus_tag="BSU05880" downshifts 633856 /Source="Nicolas_upshifts" /id="D284" /incds=0 /nref=1 /ntot=17 /MaxReadThrough="1.56881" /MaxDrop="2.87204" /score="7.63230089" /energy="-5.4" /TU="NA" /idTUdmin="U454" /TUdmin=0 /isTUend="TRUE" CDS complement(633923..634651) /gene="ydhUc" /locus_tag="BSU_05890" /old_locus_tag="BSU05890" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function; Product type e : enzyme" /pseudo /codon_start=1 /transl_table=11 /product="Mn catalase fragment; C-terminal part of YhdU" /db_xref="SubtiList:BG12198" /translation="FFQSSNFRGKQKQYRDLLRGIFLEEIAHVELVQNTINALLDESG GEGVGSQGTDQAPLDEAVKHANPHHYIIGAQSSLPVDAGGNPWNGSWVYNHGNLITDL LDNLLLESTGVLQKTRIYEMSSNQTFRETLAFLIVRDNAHQNAFAKALETLGVEWAKL LPVPNYDINKYPECRKYVELGYHNTHFNFRLDETRISEIYQGKSPSRNGGELQVIDPP AGFPVPVLPEIPNEHSPGLGDMNA*" gene complement(633923..634651) /gene="ydhUc" /locus_tag="BSU_05890" /old_locus_tag="BSU05890" /pseudo downshifts complement(633973) /Source="Nicolas_upshifts" /id="D285" /incds=0 /nref=13 /ntot=37 /MaxReadThrough="1.1517" /MaxDrop="5.0503" /score="0.317473754" /energy="-17.6" /TU="NA" /idTUdmin="U456" /TUdmin=3 /isTUend="TRUE" CDS complement(634582..634776) /gene="ydhUn" /locus_tag="BSU_05899" /old_locus_tag="BSU05899" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function; Product type e : enzyme" /pseudo /codon_start=1 /transl_table=11 /product="Mn catalase fragment; N-terminal part of YhdU" /translation="MYYYKEELINIIKPDKPDPAAAKVLQEILGGHYGEMRTMMQFFS KALISEESRNSTAICFAAFF*" gene complement(634582..634776) /gene="ydhUn" /locus_tag="BSU_05899" /old_locus_tag="BSU05899" /pseudo promotor_-10 complement(634809..634820) /Source="Nicolas_upshift_promotors" /id="U456" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.994005994005994" /psig="0.994005994005994" /xcortree=907 /SigmaFactorBS="ttattttcttctttcacgccttcccatgcttatcatgTATAT ATtttatctcatcttACAAATAATATAagaaaatctcttaagaagaaatgaggcgtgt t" /listShort="ydhU, ydhU" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(634817) /Source="Nicolas_upshifts" /id="U456" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.994005994005994" /psig="0.994005994005994" /xcortree=907 /SigmaFactorBS="ttattttcttctttcacgccttcccatgcttatcatgTATAT ATtttatctcatcttACAAATAATATAagaaaatctcttaagaagaaatgaggcgtgt t" /listShort="ydhU, ydhU" /GFF_Attribute="listLong" promotor_-35 complement(634834..634840) /Source="Nicolas_upshift_promotors" /id="U456" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.994005994005994" /psig="0.994005994005994" /xcortree=907 /SigmaFactorBS="ttattttcttctttcacgccttcccatgcttatcatgTATAT ATtttatctcatcttACAAATAATATAagaaaatctcttaagaagaaatgaggcgtgt t" /listShort="ydhU, ydhU" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 634895..634902 /Source="Nicolas_upshift_promotors" /id="U457" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.998001998001998" /psig=1 /xcortree=2625 /SigmaFactorBS="cgtgaaagaagaaaataaaaaaatacaggaaaagtGTTGACC AaataaaacaggcaTGGTATATTATTAAACGTCGctgatgaacagcgtgaaacaaaac a" /listShort="S204, trnE-Arg, trnE-Gly, rrnE-16S" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 634916..634935 /Source="Nicolas_upshift_promotors" /id="U457" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.998001998001998" /psig=1 /xcortree=2625 /SigmaFactorBS="cgtgaaagaagaaaataaaaaaatacaggaaaagtGTTGACC AaataaaacaggcaTGGTATATTATTAAACGTCGctgatgaacagcgtgaaacaaaac a" /listShort="S204, trnE-Arg, trnE-Gly, rrnE-16S" /GFF_Attribute="listLong" /label="promotor_-10" promotor_no_box 634918..635018 /Source="Nicolas_upshift_promotors" /id="U458" /multdbtbs="-" /comp="M21" /sig="Sig-" /pcomp="0.604395604395604" /psig="0.0919080919080919" /xcortree=1636 /SigmaFactorBS="gtatattattaaacgtcgctgatgaacagcgtgaaacaaaac agaaaaacaaaaaagttttcctaaggtgtttacaagattttaaaaatgtgtataataa g" /listShort="S204, trnE-Arg, trnE-Gly, rrnE-16S" /GFF_Attribute="listLong" /label="promotor_no_box" upshifts 634920 /Source="Nicolas_upshifts" /id="U457" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.998001998001998" /psig=1 /xcortree=2625 /SigmaFactorBS="cgtgaaagaagaaaataaaaaaatacaggaaaagtGTTGACC AaataaaacaggcaTGGTATATTATTAAACGTCGctgatgaacagcgtgaaacaaaac a" /listShort="S204, trnE-Arg, trnE-Gly, rrnE-16S" /GFF_Attribute="listLong" downshifts complement(634966) /Source="Nicolas_upshifts" /id="D286" /incds=0 /nref=1 /ntot=54 /MaxReadThrough="2.24619" /MaxDrop="4.20389" /score="11.9939391" /energy="-9" /TU="NA" /idTUdmin="U456" /TUdmin="-990" /isTUend="FALSE" upshifts 634978 /Source="Nicolas_upshifts" /id="U458" /multdbtbs="-" /comp="M21" /sig="Sig-" /pcomp="0.604395604395604" /psig="0.0919080919080919" /xcortree=1636 /SigmaFactorBS="gtatattattaaacgtcgctgatgaacagcgtgaaacaaaac agaaaaacaaaaaagttttcctaaggtgtttacaagattttaaaaatgtgtataataa g" /listShort="S204, trnE-Arg, trnE-Gly, rrnE-16S" /GFF_Attribute="listLong" promotor_-35 634986..634993 /Source="Nicolas_upshift_promotors" /id="U459" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.418581418581419" /psig="0.96003996003996" /xcortree=1634 /SigmaFactorBS="aaaaacaaaaaagttttcctaaggTGTTTACAagattttaaa aatGTGTATAATAAGAAAAGTCGaattgaaaaagattcgaaaaaacattaaaaaactt c" /listShort="S204, trnE-Arg, trnE-Gly, rrnE-16S" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 635007..635026 /Source="Nicolas_upshift_promotors" /id="U459" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.418581418581419" /psig="0.96003996003996" /xcortree=1634 /SigmaFactorBS="aaaaacaaaaaagttttcctaaggTGTTTACAagattttaaa aatGTGTATAATAAGAAAAGTCGaattgaaaaagattcgaaaaaacattaaaaaactt c" /listShort="S204, trnE-Arg, trnE-Gly, rrnE-16S" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 635022..635109 /Source="Nicolas_S_feature" /locus_tag="new_635022_635109" /HighExp="LBGstat, C30, Cold, Heat, Oxctl, T-1.10H, T-0.40H, T-1.40H, UNK1, BMM" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, Sig-, SigA" /TUshortPSig="0.96, 0.0919, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S204" upshifts 635022 /Source="Nicolas_upshifts" /id="U459" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.418581418581419" /psig="0.96003996003996" /xcortree=1634 /SigmaFactorBS="aaaaacaaaaaagttttcctaaggTGTTTACAagattttaaa aatGTGTATAATAAGAAAAGTCGaattgaaaaagattcgaaaaaacattaaaaaactt c" /listShort="S204, trnE-Arg, trnE-Gly, rrnE-16S" /GFF_Attribute="listLong" tRNA 635110..635186 /gene="trnE-Arg" /locus_tag="BSU_tRNA_79" /product="tRNA-Arg" /inference="profile:tRNAscan:1.23" /note="Evidence 2a: Function from experimental evidences in other organisms; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene 635110..635186 /gene="trnE-Arg" /locus_tag="BSU_tRNA_79" tRNA 635200..635273 /gene="trnE-Gly" /locus_tag="BSU_tRNA_80" /product="tRNA-Gly" /inference="profile:tRNAscan:1.23" /note="transfer RNA-Gly(UCC); Evidence 2a: Function from experimental evidences in other organisms; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene 635200..635273 /gene="trnE-Gly" /locus_tag="BSU_tRNA_80" rRNA 635433..636987 /gene="rrnE-16S" /locus_tag="BSU_rRNA_30" /product="ribosomal RNA-16S" /note="Evidence 1a: Function from experimental evidences in the studied strain; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene 635433..636987 /gene="rrnE-16S" /locus_tag="BSU_rRNA_30" rRNA 637155..640082 /gene="rrnE-23S" /locus_tag="BSU_rRNA_12" /product="ribosomal RNA-23S" /note="Evidence 1a: Function from experimental evidences in the studied strain; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene 637155..640082 /gene="rrnE-23S" /locus_tag="BSU_rRNA_12" rRNA 640138..640254 /gene="rrnE-5S" /locus_tag="BSU_rRNA_13" /product="ribosomal RNA-5S" /note="Evidence 1a: Function from experimental evidences in the studied strain; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene 640138..640254 /gene="rrnE-5S" /locus_tag="BSU_rRNA_13" tRNA 640268..640344 /gene="trnE-Met" /locus_tag="BSU_tRNA_21" /product="tRNA-Met" /inference="profile:tRNAscan:1.23" /note="transfer RNA-Met(CAU); Evidence 1a: Function from experimental evidences in the studied strain; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene 640268..640344 /gene="trnE-Met" /locus_tag="BSU_tRNA_21" tRNA 640405..640481 /gene="trnE-Asp" /locus_tag="BSU_tRNA_22" /product="tRNA-Asp" /inference="profile:tRNAscan:1.23" /note="transfer RNA-Asp(GUC); Evidence 2a: Function from experimental evidences in other organisms; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene 640405..640481 /gene="trnE-Asp" /locus_tag="BSU_tRNA_22" downshifts 640478 /Source="Nicolas_upshifts" /id="D287" /incds=0 /nref=38 /ntot=211 /MaxReadThrough="6.00554" /MaxDrop="5.14761" /score="7.63230089" /energy="-5.4" /TU="NA" /idTUdmin="U460" /TUdmin="-3784" /isTUend="FALSE" promotor_-35 640582..640586 /Source="Nicolas_upshift_promotors" /id="U460" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.942057942057942" /psig=1 /xcortree=2461 /SigmaFactorBS="tggtgtcatagccaagctttctttatatcgggaacaTCTTGg atattccagcaaaaTTCGATAAACTAGGAAGAGCacaaataggcataagcagggttga a" /listShort="thiL, ydiB, ydiC, rimI, gcp" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 640602..640621 /Source="Nicolas_upshift_promotors" /id="U460" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.942057942057942" /psig=1 /xcortree=2461 /SigmaFactorBS="tggtgtcatagccaagctttctttatatcgggaacaTCTTGg atattccagcaaaaTTCGATAAACTAGGAAGAGCacaaataggcataagcagggttga a" /listShort="thiL, ydiB, ydiC, rimI, gcp" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 640606 /Source="Nicolas_upshifts" /id="U460" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.942057942057942" /psig=1 /xcortree=2461 /SigmaFactorBS="tggtgtcatagccaagctttctttatatcgggaacaTCTTGg atattccagcaaaaTTCGATAAACTAGGAAGAGCacaaataggcataagcagggttga a" /listShort="thiL, ydiB, ydiC, rimI, gcp" /GFF_Attribute="listLong" CDS 640662..641639 /gene="thiL" /locus_tag="BSU_05900" /old_locus_tag="BSU05900" /EC_number="2.7.4.16" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 16291685, 26443755; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="thiamine-monophosphate kinase" /protein_id="NP_388471.1" /db_xref="EnsemblGenomes-Gn:BSU05900" /db_xref="EnsemblGenomes-Tr:CAB12409" /db_xref="GOA:O05514" /db_xref="InterPro:IPR006283" /db_xref="InterPro:IPR010918" /db_xref="InterPro:IPR016188" /db_xref="InterPro:IPR036676" /db_xref="InterPro:IPR036921" /db_xref="SubtiList:BG10693" /db_xref="UniProtKB/Swiss-Prot:O05514" /translation="MDEFDLIHSITPRTIHHSSVDVGIGDDAALYTAKHGVQEIVCVD TMVEDVHFKLHYSSPEDIGYKALAVNISDIAAMGGIPKFYLVSLAVPSKWTESEIKAM YEGMNELAKLYHMDLIGGDTVSTADKLVVTVTVIGEIEKGQACLRSLAKPNDIVFVTG EIGSSAAGLSLLLEETNPQNSSVETDYFIHRHKRPEPRVSVGRLCSIFKRAALNDVSD GLASELNEIAEASCVSIEIVESMLPIHSDLPKLHPNWKEWALFGGEDFELTGTVSNEE WEVLKQECAALHLPITKIGYVREKTKSKVILKTDQTSMILEKKGYNHFK*" gene 640662..641639 /gene="thiL" /locus_tag="BSU_05900" /old_locus_tag="BSU05900" CDS 641654..642130 /gene="tsaE" /locus_tag="BSU_05910" /old_locus_tag="BSU05910" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:12682299, 17005971, 19246765, 19376873, 19578062, 20701780, 20824107, 21183954, 21285948, 22378793, 23072323" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12682299, 17005971, 19246765, 19376873, 19578062, 20701780, 20824107, 21183954, 21285948, 22378793, 23072323; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="tRNA(NNU) t(6)A37 threonylcarbamoyladenosine modification; ADP binding protein" /protein_id="NP_388472.1" /db_xref="EnsemblGenomes-Gn:BSU05910" /db_xref="EnsemblGenomes-Tr:CAB12410" /db_xref="GOA:O05515" /db_xref="InterPro:IPR003442" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG12199" /db_xref="UniProtKB/Swiss-Prot:O05515" /translation="MKQLKWRTVNPEETKAIAKLTAAFAKPGDVLTLEGDLGAGKTTF TKGFAEGLGITRIVNSPTFTIIKEYNDGVLPLYHMDVYRMEDESEDLGLDEYFHGQGV CLVEWAHLIEEQLPQERLQIVIKRAGDDEREITFTAVGNRYEMLCEELSRHDNISN*" gene 641654..642130 /gene="tsaE" /locus_tag="BSU_05910" /old_locus_tag="BSU05910" CDS 642111..642800 /gene="tsaB" /locus_tag="BSU_05920" /old_locus_tag="BSU05920" /function="16.2: Construct biomass (Anabolism)" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:12682299, 17005971, 20944216, 19376873, 19578062, 20701780, 20824107, 21183954, 21285948, 22378793, 23072323" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12682299, 17005971, 20944216, 19376873, 19578062, 20701780, 20824107, 21183954, 21285948, 22378793, 23072323; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="tRNA(NNU) t(6)A37 threonylcarbamoyladenosine modification; protease involved in TsaD function" /protein_id="NP_388473.1" /db_xref="EnsemblGenomes-Gn:BSU05920" /db_xref="EnsemblGenomes-Tr:CAB12411" /db_xref="GOA:O05516" /db_xref="InterPro:IPR000905" /db_xref="InterPro:IPR022496" /db_xref="SubtiList:BG12200" /db_xref="UniProtKB/Swiss-Prot:O05516" /translation="MTILAIDTSNYTLGIALLREDTVIAEYITYLKKNHSVRAMPAVH SLLNDCDMAPQDLSKIVVAKGPGSYTGVRIGVTLAKTLAWSLDIPISAVSSLETLAAN GRHFDGLISPIFDARRGQVYTGLYQYKNGLLEQVVPDQNVMLADWLEMLKEKDRPVLF LGHDTSLHKQMIEDVLGTKGFIGTAAQHNPRPSELAFLGKEKEAADVHGLVPDYLRLA EAEAKWIESQK*" gene 642111..642800 /gene="tsaB" /locus_tag="BSU_05920" /old_locus_tag="BSU05920" CDS 642810..643265 /gene="rimI" /locus_tag="BSU_05930" /old_locus_tag="BSU05930" /EC_number="2.3.1.267" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 2828880; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="ribosomal protein S18 alanine N-acetyltransferase" /protein_id="NP_388474.1" /db_xref="EnsemblGenomes-Gn:BSU05930" /db_xref="EnsemblGenomes-Tr:CAB12412" /db_xref="GOA:O05517" /db_xref="InterPro:IPR000182" /db_xref="InterPro:IPR006464" /db_xref="InterPro:IPR016181" /db_xref="SubtiList:BG12201" /db_xref="UniProtKB/Swiss-Prot:O05517" /translation="MKTKAAVRNMRLEDIDHVYEIEASSFTSPWTKDSFYHELLENPY AHYLVIEKDGHLAGYCGIWIVMDDAQITNIAIKPEYRGQSLGETLFRSAVELCKEKDA RRLSLEVRVSNHPAQGLYKKFGMQPGGIRKNYYTDNGEDALIMWVTINE*" gene 642810..643265 /gene="rimI" /locus_tag="BSU_05930" /old_locus_tag="BSU05930" CDS 643258..644298 /gene="tsaD" /locus_tag="BSU_05940" /old_locus_tag="BSU05940" /function="16.2: Construct biomass (Anabolism)" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 11073929, 12682299, 9743119, 20824107, 21625506, 21873492, 19376873, 19578062, 20701780, 20824107, 21183954, 21285948, 22378793; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="tRNA(NNU) t(6)A37 threonylcarbamoyladenosine modification; glycation binding protein" /protein_id="NP_388475.1" /db_xref="EnsemblGenomes-Gn:BSU05940" /db_xref="EnsemblGenomes-Tr:CAB12413" /db_xref="GOA:O05518" /db_xref="InterPro:IPR000905" /db_xref="InterPro:IPR017860" /db_xref="InterPro:IPR017861" /db_xref="InterPro:IPR022450" /db_xref="SubtiList:BG12202" /db_xref="UniProtKB/Swiss-Prot:O05518" /translation="MSEQKDMYVLGIETSCDETAAAIVKNGKEIISNVVASQIESHKR FGGVVPEIASRHHVEQITLVIEEAFRKAGMTYSDIDAIAVTEGPGLVGALLIGVNAAK ALSFAYNIPLVGVHHIAGHIYANRLVEDIVFPALALVVSGGHTELVYMKEHGSFEVIG ETLDDAAGEAYDKVARTMGLPYPGGPQIDKLAEKGNDNIPLPRAWLEEGSYNFSFSGL KSAVINTLHNASQKGQEIAPEDLSASFQNSVIDVLVTKTARAAKEYDVKQVLLAGGVA ANRGLRAALEKEFAQHEGITLVIPPLALCTDNAAMIAAAGTIAFEKGIRGAYDMNGQP GLELTSYQSLTR*" gene 643258..644298 /gene="tsaD" /locus_tag="BSU_05940" /old_locus_tag="BSU05940" downshifts 644262 /Source="Nicolas_upshifts" /id="D288" /incds=0 /nref=39 /ntot=222 /MaxReadThrough="3.15518" /MaxDrop="4.65228" /score="3.97936019" /energy="-10.1" /TU="NA" /idTUdmin="U460" /TUdmin=0 /isTUend="TRUE" CDS complement(644528..646456) /gene="ydiF" /locus_tag="BSU_05950" /old_locus_tag="BSU05950" /function="16.8: Protect" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 11916677, 16109936, 24389466; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative energy-sensing inhibitor of translation" /protein_id="NP_388476.2" /db_xref="EnsemblGenomes-Gn:BSU05950" /db_xref="EnsemblGenomes-Tr:CAB12414" /db_xref="GOA:O05519" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR017871" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR032524" /db_xref="InterPro:IPR032781" /db_xref="SubtiList:BG12203" /db_xref="UniProtKB/Swiss-Prot:O05519" /translation="MMILQVNQLSKSFGADTILNNIKLEVRNRDRIAIVGRNGAGKST LLKIIAGQLSYEKGEIIKPKDITMGYLAQHTGLDSKLTIKEELLTVFDHLKAMEKEMR AMEEKMAAADPGELESIMKTYDRLQQEFKDKGGYQYEADVRSVLHGLGFSHFDDSTQV QSLSGGQKTRLALGKLLLTQPDLLILDEPTNHLDIDTLTWLEHYLQGYSGAILIVSHD RYFLDKVVNQVYEVSRAESKKYHGNYSAYLDQKAAQYEKDLKMYEKQQDEIAKLQDFV DRNLARASTTKRAQSRRKQLERMDVMSKPLGDEKSANFHFDITKQSGNEVLRVQDLTI SYENQPPLLTEVSFMLTRGESAALVGPNGIGKSTLLKTLIDTLKPDQGTISYGSNVSV GYYDQEQAELTSSKRVLDELWDEYPGLPEKEIRTCLGNFLFSGDDVLKPVHSLSGGEK ARLALAKLMLQKANFLILDEPTNHLDLDSKEVLENALIDYPGTLLFVSHDRYFINRIA TRVLELSSSHIEEYLGDYDYYTEKKTEQLELEKMNQQEETDKTPATVKSDSKRSYEEE KEWKKKERQRLRRIEEIETTVQTIEENISRNDELLCDPEVYQDHEKVQAIHADNEKLN QELESLLSEWEELSTEED*" gene complement(644528..646456) /gene="ydiF" /locus_tag="BSU_05950" /old_locus_tag="BSU05950" downshifts complement(644545) /Source="Nicolas_upshifts" /id="D289" /incds=0 /nref=170 /ntot=266 /MaxReadThrough="1.32926" /MaxDrop="5.81869" /score="16.702581" /energy="-12.6" /TU="NA" /idTUdmin="U463" /TUdmin="-9" /isTUend="TRUE" misc_feature 646208..646227 /Source="Nicolas_upshift_promotors" /id="U461" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.821178821178821" /psig="0.98901098901099" /xcortree=2080 /SigmaFactorBS="tccttttccattgcttttaagtggtcaaaaacagtcagcagc tcttctttTATGGTAAGCTTAGAATCCAagccagtatgctgggcgagatatcccattg t" /listShort="S205, S206, moaC, rex, tatAY, tatCY" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 646218 /Source="Nicolas_upshifts" /id="U461" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.821178821178821" /psig="0.98901098901099" /xcortree=2080 /SigmaFactorBS="tccttttccattgcttttaagtggtcaaaaacagtcagcagc tcttctttTATGGTAAGCTTAGAATCCAagccagtatgctgggcgagatatcccattg t" /listShort="S205, S206, moaC, rex, tatAY, tatCY" /GFF_Attribute="listLong" S_feature 646220..646409 /Source="Nicolas_S_feature" /locus_tag="new_646220_646409" /HighExp="Diami, H2O2, dia5, Paraq, G135, G180, G150, Cold, dia15, BC" /AntisenseName="ydiF" /AntisenseCor="0.47406689574609401" /AntisenseRegPval="-15.8" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.989" /TUlongSig="NA" /TUlongPSig="NA" /label="S205" promotor_-35 646374..646381 /Source="Nicolas_upshift_promotors" /id="U462" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.93006993006993" /psig="0.997002997002997" /xcortree=2055 /SigmaFactorBS="ctacaatggcgatgcgatcacgaTTTCTGACttccagcttta taTTGTTTAAAATAGTATCAGCaccaaatgatttggacagctgattaacttgtaagat c" /listShort="S206, moaC, rex, tatAY, tatCY" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 646395..646414 /Source="Nicolas_upshift_promotors" /id="U462" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.93006993006993" /psig="0.997002997002997" /xcortree=2055 /SigmaFactorBS="ctacaatggcgatgcgatcacgaTTTCTGACttccagcttta taTTGTTTAAAATAGTATCAGCaccaaatgatttggacagctgattaacttgtaagat c" /listShort="S206, moaC, rex, tatAY, tatCY" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 646411..646581 /Source="Nicolas_S_feature" /locus_tag="new_646411_646581" /HighExp="Diami, dia5, dia15, H2O2, Etha, G180, G150, Oxctl, Mt0, Paraq" /AntisenseName="ydiF" /AntisenseCor="0.63697451027099605" /AntisenseRegPval="-31.3" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="0.997, 0.989" /TUlongSig="NA" /TUlongPSig="NA" /label="S206" upshifts 646411 /Source="Nicolas_upshifts" /id="U462" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.93006993006993" /psig="0.997002997002997" /xcortree=2055 /SigmaFactorBS="ctacaatggcgatgcgatcacgaTTTCTGACttccagcttta taTTGTTTAAAATAGTATCAGCaccaaatgatttggacagctgattaacttgtaagat c" /listShort="S206, moaC, rex, tatAY, tatCY" /GFF_Attribute="listLong" promotor_-10 complement(646476..646495) /Source="Nicolas_upshift_promotors" /id="U463" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.891108891108891" /psig="0.999000999001" /xcortree=2085 /SigmaFactorBS="tttcttctctatgtcttatatggccaatgtatTGTTTGCTga cttctggttcaTAAGCTACACTTAACTTATTatagcagaggtgaaataatatgatgat c" /listShort="ydiF" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(646488) /Source="Nicolas_upshifts" /id="U463" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.891108891108891" /psig="0.999000999001" /xcortree=2085 /SigmaFactorBS="tttcttctctatgtcttatatggccaatgtatTGTTTGCTga cttctggttcaTAAGCTACACTTAACTTATTatagcagaggtgaaataatatgatgat c" /listShort="ydiF" /GFF_Attribute="listLong" promotor_-35 complement(646509..646516) /Source="Nicolas_upshift_promotors" /id="U463" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.891108891108891" /psig="0.999000999001" /xcortree=2085 /SigmaFactorBS="tttcttctctatgtcttatatggccaatgtatTGTTTGCTga cttctggttcaTAAGCTACACTTAACTTATTatagcagaggtgaaataatatgatgat c" /listShort="ydiF" /GFF_Attribute="listLong" /label="promotor_-35" CDS 646582..647094 /gene="moaC" /locus_tag="BSU_05960" /old_locus_tag="BSU05960" /EC_number="4.6.1.17" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 10903949, 16632608, 18607082, 20606263, 25941396, 26575208; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="molybdenum cofactor biosynthesis protein C" /protein_id="NP_388477.1" /db_xref="EnsemblGenomes-Gn:BSU05960" /db_xref="EnsemblGenomes-Tr:CAB12415" /db_xref="GOA:O05520" /db_xref="InterPro:IPR002820" /db_xref="InterPro:IPR023045" /db_xref="InterPro:IPR036522" /db_xref="SubtiList:BG12204" /db_xref="UniProtKB/Swiss-Prot:O05520" /translation="MNGFSHFNEQGRAQMVDISEKSSTVRTAAAVSSVHMKNEVYEKI QSHDIGKGDVLAVAQVAGIMAAKQTSNIIPMCHPLSLSGVDISFDWKIKEAEVILHIK AQVKTKGSTGVEMEALTSASVCALTVYDMCKALDKGMVIGPTFLLEKTGGKNGDFKRE LSEYNLEDQK*" gene 646582..647094 /gene="moaC" /locus_tag="BSU_05960" /old_locus_tag="BSU05960" CDS 647091..647738 /gene="rex" /locus_tag="BSU_05970" /old_locus_tag="BSU05970" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:15231791, 16207915, 17015645, 17322317, 18485070, 21402078, 23046954, 26735940" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15231791, 16207915, 17015645, 17322317, 18485070, 21402078, 23046954, 26735940; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcription repressor of cydABCD and yjlC-ndh expression" /protein_id="NP_388478.1" /db_xref="EnsemblGenomes-Gn:BSU05970" /db_xref="EnsemblGenomes-Tr:CAB12416" /db_xref="GOA:O05521" /db_xref="InterPro:IPR003781" /db_xref="InterPro:IPR009718" /db_xref="InterPro:IPR022876" /db_xref="InterPro:IPR036291" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="PDB:2VT2" /db_xref="PDB:2VT3" /db_xref="SubtiList:BG12205" /db_xref="UniProtKB/Swiss-Prot:O05521" /translation="MNKDQSKIPQATAKRLPLYYRFLKNLHASGKQRVSSAELSDAVK VDSATIRRDFSYFGALGKKGYGYNVDYLLSFFRKTLDQDEMTDVILIGVGNLGTAFLH YNFTKNNNTKISMAFDINESKIGTEVGGVPVYNLDDLEQHVKDESVAILTVPAVAAQS ITDRLVALGIKGILNFTPARLNVPEHIRIHHIDLAVELQSLVYFLKHYSVLEEIE*" gene 647091..647738 /gene="rex" /locus_tag="BSU_05970" /old_locus_tag="BSU05970" promotor_no_box 647568..647668 /Source="Nicolas_upshift_promotors" /id="U464" /multdbtbs="-" /comp="M2" /sig="Sig-" /pcomp="0.386613386613387" /psig="0.386613386613387" /xcortree=511 /SigmaFactorBS="tccattacagacagattggtcgcattaggaatcaagggaatc cttaattttacgccggcccgtttgaatgtgccggaacacattcgaattcatcatatag a" /listShort="tatAY, tatCY" /GFF_Attribute="listLong" /label="promotor_no_box" upshifts 647628 /Source="Nicolas_upshifts" /id="U464" /multdbtbs="-" /comp="M2" /sig="Sig-" /pcomp="0.386613386613387" /psig="0.386613386613387" /xcortree=511 /SigmaFactorBS="tccattacagacagattggtcgcattaggaatcaagggaatc cttaattttacgccggcccgtttgaatgtgccggaacacattcgaattcatcatatag a" /listShort="tatAY, tatCY" /GFF_Attribute="listLong" CDS 647760..647933 /gene="tatAY" /locus_tag="BSU_05980" /old_locus_tag="BSU05980" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:15187182, 19049517, 22041895, 22544248, 24652282, 26239117, 22720735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15187182, 19049517, 22041895, 22544248, 24652282, 26239117, 22720735; Product type t: transporter" /codon_start=1 /transl_table=11 /product="component of the twin-arginine pre-protein translocation pathway" /protein_id="NP_388479.1" /db_xref="EnsemblGenomes-Gn:BSU05980" /db_xref="EnsemblGenomes-Tr:CAB12417" /db_xref="GOA:O05522" /db_xref="InterPro:IPR003369" /db_xref="InterPro:IPR006312" /db_xref="SubtiList:BG12206" /db_xref="UniProtKB/Swiss-Prot:O05522" /translation="MPIGPGSLAVIAIVALIIFGPKKLPELGKAAGDTLREFKNATKG LTSDEEEKKKEDQ*" gene 647760..647933 /gene="tatAY" /locus_tag="BSU_05980" /old_locus_tag="BSU05980" CDS 647940..648704 /gene="tatCY" /locus_tag="BSU_05990" /old_locus_tag="BSU05990" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:11007775, 15187182, 15849754, 16850406, 19049517, 22720735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11007775, 15187182, 15849754, 16850406, 19049517, 22720735; Product type t : transporter" /codon_start=1 /transl_table=11 /product="component of the twin-arginine pre-protein translocation pathway" /protein_id="NP_388480.1" /db_xref="EnsemblGenomes-Gn:BSU05990" /db_xref="EnsemblGenomes-Tr:CAB12418" /db_xref="GOA:O05523" /db_xref="InterPro:IPR002033" /db_xref="InterPro:IPR019820" /db_xref="SubtiList:BG12207" /db_xref="UniProtKB/Swiss-Prot:O05523" /translation="MTRMKVNQMSLLEHIAELRKRLLIVALAFVVFFIAGFFLAKPII VYLQETDEAKQLTLNAFNLTDPLYVFMQFAFIIGIVLTSPVILYQLWAFVSPGLYEKE RKVTLSYIPVSILLFLAGLSFSYYILFPFVVDFMKRISQDLNVNQVIGINEYFHFLLQ LTIPFGLLFQMPVILMFLTRLGIVTPMFLAKIRKYAYFTLLVIAALITPPELLSHMMV TVPLLILYEISILISKAAYRKAQKSSAADRDVSSGQ*" gene 647940..648704 /gene="tatCY" /locus_tag="BSU_05990" /old_locus_tag="BSU05990" downshifts 648684 /Source="Nicolas_upshifts" /id="D290" /incds=0 /nref=151 /ntot=251 /MaxReadThrough="4.01237" /MaxDrop="6.80817" /score="19.4098216" /energy="-12.7" /TU="NA" /idTUdmin="U461" /TUdmin=0 /isTUend="TRUE" CDS complement(648742..648933) /gene="ydiK" /locus_tag="BSU_06000" /old_locus_tag="BSU06000" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_388481.1" /db_xref="EnsemblGenomes-Gn:BSU06000" /db_xref="EnsemblGenomes-Tr:CAB12419" /db_xref="GOA:O05524" /db_xref="InterPro:IPR025426" /db_xref="SubtiList:BG12208" /db_xref="UniProtKB/Swiss-Prot:O05524" /translation="MRNPVVWGMIYFAVGCIFTYLAASSPGSMWSFYSILLMVFAAYN ISISFKMFAFSFKIKKNQK*" gene complement(648742..648933) /gene="ydiK" /locus_tag="BSU_06000" /old_locus_tag="BSU06000" downshifts complement(648759) /Source="Nicolas_upshifts" /id="D291" /incds=0 /nref=211 /ntot=258 /MaxReadThrough="0.81338" /MaxDrop="6.43897" /score="25.5376889" /energy="-12.7" /TU="NA" /idTUdmin="U467" /TUdmin="-21" /isTUend="TRUE" CDS complement(648930..649664) /gene="ydiL" /locus_tag="BSU_06010" /old_locus_tag="BSU06010" /EC_number="3.4.-.-" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative membrane protease" /protein_id="NP_388482.1" /db_xref="EnsemblGenomes-Gn:BSU06010" /db_xref="EnsemblGenomes-Tr:CAB12420" /db_xref="GOA:O05525" /db_xref="InterPro:IPR003675" /db_xref="SubtiList:BG12209" /db_xref="UniProtKB/Swiss-Prot:O05525" /translation="MRKQYWFIILTYIIMQFSALIAIPLLFKFGYAGGQPTDENMLHA QGLWSVISFIACLVVVLLILRTVPKETLRNGQKDSIGLSILWAIAGFFIALFSQGIAG SIEYYVFGIGRESENTQAILDVIQAVPLMIIVSSIVGPILEEIIFRKIIFGALYEKTN FFFAGLISSVIFGIVHADLKHLLLYTAMGFTFAFLYARTKRIWVPIFAHLMMNTFVVI MQLEPVRNYLEQQSTQMQLIIGGLFL*" gene complement(648930..649664) /gene="ydiL" /locus_tag="BSU_06010" /old_locus_tag="BSU06010" promotor_-35 649322..649327 /Source="Nicolas_upshift_promotors" /id="U465" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.952047952047952" /psig="0.952047952047952" /xcortree=1034 /SigmaFactorBS="tgcctgaatgacatccagaatcgcttgtgtattttctgATTC TCttccgatgccaaaaACATAATATTCAATAGAGCctgctattccttgagagaaaagg g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 649342..649360 /Source="Nicolas_upshift_promotors" /id="U465" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.952047952047952" /psig="0.952047952047952" /xcortree=1034 /SigmaFactorBS="tgcctgaatgacatccagaatcgcttgtgtattttctgATTC TCttccgatgccaaaaACATAATATTCAATAGAGCctgctattccttgagagaaaagg g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 649344 /Source="Nicolas_upshifts" /id="U465" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.952047952047952" /psig="0.952047952047952" /xcortree=1034 /SigmaFactorBS="tgcctgaatgacatccagaatcgcttgtgtattttctgATTC TCttccgatgccaaaaACATAATATTCAATAGAGCctgctattccttgagagaaaagg g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 649663..649664 /Source="Nicolas_upshift_promotors" /id="U466" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.508491508491508" /psig="0.237762237762238" /xcortree=1461 /SigmaFactorBS="aaaataataaaccaatactgttttctcAAatggtatgtACTC CTTTGTTAAGTgggtttcgttcatctacagctattgtaacataatcggtacgggggtg a" /listShort="S207" /listLong="S208, groES, groEL, S209, S210, ydiM, S211, ydzU, ydzV, S212, S213, ydiO, ydiP" /label="promotor_-35" promotor_-10 649674..649688 /Source="Nicolas_upshift_promotors" /id="U466" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.508491508491508" /psig="0.237762237762238" /xcortree=1461 /SigmaFactorBS="aaaataataaaccaatactgttttctcAAatggtatgtACTC CTTTGTTAAGTgggtttcgttcatctacagctattgtaacataatcggtacgggggtg a" /listShort="S207" /listLong="S208, groES, groEL, S209, S210, ydiM, S211, ydzU, ydzV, S212, S213, ydiO, ydiP" /label="promotor_-10" upshifts 649696 /Source="Nicolas_upshifts" /id="U466" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.508491508491508" /psig="0.237762237762238" /xcortree=1461 /SigmaFactorBS="aaaataataaaccaatactgttttctcAAatggtatgtACTC CTTTGTTAAGTgggtttcgttcatctacagctattgtaacataatcggtacgggggtg a" /listShort="S207" /listLong="S208, groES, groEL, S209, S210, ydiM, S211, ydzU, ydzV, S212, S213, ydiO, ydiP" promotor_-10 complement(649701..649720) /Source="Nicolas_upshift_promotors" /id="U467" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.671328671328671" /psig=1 /xcortree=2332 /SigmaFactorBS="tcacgcttacatcattcttttccgctcccttttccgttagct TTTTCAcccccgtaccgatTATGTTACAATAGCTGTAGAtgaacgaaacccacttaac a" /listShort="ydiL, ydiK" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 649718..649826 /Source="Nicolas_S_feature" /locus_tag="new_649718_649826" /HighExp="S4, S5, H2O2, S3, S8, S6, Diami, Oxctl, G180, dia15" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="Sig-" /TUshortPSig="0.238" /TUlongSig="NA" /TUlongPSig="NA" /label="S207" upshifts complement(649721) /Source="Nicolas_upshifts" /id="U467" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.671328671328671" /psig=1 /xcortree=2332 /SigmaFactorBS="tcacgcttacatcattcttttccgctcccttttccgttagct TTTTCAcccccgtaccgatTATGTTACAATAGCTGTAGAtgaacgaaacccacttaac a" /listShort="ydiL, ydiK" /GFF_Attribute="listLong" promotor_-35 complement(649734..649739) /Source="Nicolas_upshift_promotors" /id="U467" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.671328671328671" /psig=1 /xcortree=2332 /SigmaFactorBS="tcacgcttacatcattcttttccgctcccttttccgttagct TTTTCAcccccgtaccgatTATGTTACAATAGCTGTAGAtgaacgaaacccacttaac a" /listShort="ydiL, ydiK" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 649800..649806 /Source="Nicolas_upshift_promotors" /id="U468" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.495504495504495" /psig="0.999000999001" /xcortree=2363 /SigmaFactorBS="tgatgtaagcgtgaaaaattttttatcttatcACTTGAAatt ggaagggagaTTCTTTATTATAAGAATTGTgttagcactctttagtgctgagtgctaa a" /listShort="S208, groES, groEL, S209, S210, ydiM, S211, ydzU, ydzV, S212, S213, ydiO, ydiP" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 649820..649839 /Source="Nicolas_upshift_promotors" /id="U468" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.495504495504495" /psig="0.999000999001" /xcortree=2363 /SigmaFactorBS="tgatgtaagcgtgaaaaattttttatcttatcACTTGAAatt ggaagggagaTTCTTTATTATAAGAATTGTgttagcactctttagtgctgagtgctaa a" /listShort="S208, groES, groEL, S209, S210, ydiM, S211, ydzU, ydzV, S212, S213, ydiO, ydiP" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 649828..649902 /Source="Nicolas_S_feature" /locus_tag="new_649828_649902" /HighExp="HiTm, Etha, dia15, Heat, C90, dia5, LoTm, Lbexp, H2O2, S1" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.999" /TUlongSig="Sig-" /TUlongPSig="0.238" /label="S208" upshifts 649828 /Source="Nicolas_upshifts" /id="U468" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.495504495504495" /psig="0.999000999001" /xcortree=2363 /SigmaFactorBS="tgatgtaagcgtgaaaaattttttatcttatcACTTGAAatt ggaagggagaTTCTTTATTATAAGAATTGTgttagcactctttagtgctgagtgctaa a" /listShort="S208, groES, groEL, S209, S210, ydiM, S211, ydzU, ydzV, S212, S213, ydiO, ydiP" /GFF_Attribute="listLong" CDS 649903..650187 /gene="groES" /locus_tag="BSU_06020" /old_locus_tag="BSU06020" /function="16.6: Maintain" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:11407116, 17031040, 9303302" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11407116, 17031040, 9303302; Product type f: factor" /codon_start=1 /transl_table=11 /product="chaperonin small subunit" /protein_id="NP_388483.2" /db_xref="EnsemblGenomes-Gn:BSU06020" /db_xref="EnsemblGenomes-Tr:CAB12421" /db_xref="GOA:P28599" /db_xref="InterPro:IPR011032" /db_xref="InterPro:IPR018369" /db_xref="InterPro:IPR020818" /db_xref="InterPro:IPR037124" /db_xref="SubtiList:BG10422" /db_xref="UniProtKB/Swiss-Prot:P28599" /translation="MLKPLGDRVVIELVESEEKTASGIVLPDSAKEKPQEGKIVAAGS GRVLESGERVALEVKEGDRIIFSKYAGTEVKYEGTEYLILRESDILAVIG*" gene 649903..650187 /gene="groES" /locus_tag="BSU_06020" /old_locus_tag="BSU06020" CDS 650234..651868 /gene="groEL" /locus_tag="BSU_06030" /old_locus_tag="BSU06030" /function="16.6: Maintain" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:9303302, 11407116, 17031040, 17420574, 22268681" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9303302, 11407116, 17031040, 17420574, 22268681; Product type f: factor" /codon_start=1 /transl_table=11 /product="chaperonin large subunit" /protein_id="NP_388484.1" /db_xref="EnsemblGenomes-Gn:BSU06030" /db_xref="EnsemblGenomes-Tr:CAB12422" /db_xref="GOA:P28598" /db_xref="InterPro:IPR001844" /db_xref="InterPro:IPR002423" /db_xref="InterPro:IPR018370" /db_xref="InterPro:IPR027409" /db_xref="InterPro:IPR027410" /db_xref="InterPro:IPR027413" /db_xref="SubtiList:BG10423" /db_xref="UniProtKB/Swiss-Prot:P28598" /translation="MAKEIKFSEEARRAMLRGVDALADAVKVTLGPKGRNVVLEKKFG SPLITNDGVTIAKEIELEDAFENMGAKLVAEVASKTNDVAGDGTTTATVLAQAMIREG LKNVTAGANPVGVRKGMEQAVAVAIENLKEISKPIEGKESIAQVAAISAADEEVGSLI AEAMERVGNDGVITIEESKGFTTELEVVEGMQFDRGYASPYMVTDSDKMEAVLDNPYI LITDKKITNIQEILPVLEQVVQQGKPLLLIAEDVEGEALATLVVNKLRGTFNAVAVKA PGFGDRRKAMLEDIAVLTGGEVITEDLGLDLKSTQIAQLGRASKVVVTKENTTIVEGA GETDKISARVTQIRAQVEETTSEFDREKLQERLAKLAGGVAVIKVGAATETELKERKL RIEDALNSTRAAVEEGIVSGGGTALVNVYNKVAAVEAEGDAQTGINIVLRALEEPIRQ IAHNAGLEGSVIVERLKNEEIGVGFNAATGEWVNMIEKGIVDPTKVTRSALQNAASVA AMFLTTEAVVADKPEENGGGAGMPDMGGMGGMGGMM*" gene 650234..651868 /gene="groEL" /locus_tag="BSU_06030" /old_locus_tag="BSU06030" S_feature 651869..651961 /Source="Nicolas_S_feature" /locus_tag="new_651869_651961" /HighExp="HiTm, Etha, dia15, Heat, Diami, dia5, C90, S1, S2, H2O2" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.999" /TUlongSig="Sig-" /TUlongPSig="0.238" /label="S209" downshifts 651918 /Source="Nicolas_upshifts" /id="D292" /incds=0 /nref=228 /ntot=267 /MaxReadThrough="6.24882" /MaxDrop="5.77437" /score="-6.71161833" /energy="-16.3" /TU="U468" /idTUdmin="U466" /TUdmin=2112 /isTUend="FALSE" CDS complement(651956..652084) /gene="ydzTc" /locus_tag="BSU_06033" /old_locus_tag="BSU06033" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /pseudo /codon_start=1 /transl_table=11 /product="hypothetical protein; putative integrase (fragment); C-terminal part of YdzT; defective prophage 3" /translation="EAGVGIKEIQQQFGHSDINTTMDIYAHMTANMEKRSPNSLVN*" gene complement(651956..652084) /gene="ydzTc" /locus_tag="BSU_06033" /old_locus_tag="BSU06033" /pseudo S_feature 651963..653431 /Source="Nicolas_S_feature" /locus_tag="new_651963_653431" /HighExp="H2O2, Heat, dia15, Diami, S1, G135, G150, S2, G180, dia5" /AntisenseName="ydzT" /AntisenseCor="-2.9485116084752801E-2" /AntisenseRegPval="-0.2" /CDS_PredictionProba="0.23100000000000001" /TUshortSig="SigA" /TUshortPSig="0.999" /TUlongSig="Sig-" /TUlongPSig="0.238" /label="S210" CDS complement(652087..652245) /gene="ydzT" /locus_tag="BSU_06034" /old_locus_tag="BSU06034" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /pseudo /codon_start=1 /transl_table=11 /product="hypothetical protein; putative integrase (fragment); internal part of YdzT" /db_xref="PSEUDO:CAX52563.1" /translation="MIYQDSSFIFEREDGHPQLRKVIETRLKRLLKKAGIKRMSPPTL LGIPIPPY*" gene complement(652087..652245) /gene="ydzT" /locus_tag="BSU_06034" /old_locus_tag="BSU06034" /pseudo CDS complement(652290..652418) /gene="ydzT" /locus_tag="BSU_06036" /old_locus_tag="BSU06036" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /pseudo /codon_start=1 /transl_table=11 /product="hypothetical protein; putative integrase (fragment); internal part of YdzT" /db_xref="PSEUDO:CAX52564.1" /translation="MISQVTKTLYTPNNQIEKYQLLTPKTTGSVDIVRIDETMSIY*" gene complement(652290..652418) /gene="ydzT" /locus_tag="BSU_06036" /old_locus_tag="BSU06036" /pseudo CDS complement(652511..652720) /gene="ydzT" /locus_tag="BSU_06037" /old_locus_tag="BSU06037" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function; Product type e : enzyme" /pseudo /codon_start=1 /transl_table=11 /product="hypothetical protein; putative integrase (fragment); internal part of YdzT" /db_xref="PSEUDO:CAX52565.1" /translation="MYEDRTLELNEQYSHNCLGGIHACGRMIFRKAKTQGIIKMNPTG DFQLPKKQQSIGKRGADTFSKARSI*" gene complement(652511..652720) /gene="ydzT" /locus_tag="BSU_06037" /old_locus_tag="BSU06037" /pseudo CDS complement(652713..653018) /gene="ydzTn" /locus_tag="BSU_06038" /old_locus_tag="BSU06038" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /pseudo /codon_start=1 /transl_table=11 /product="hypothetical protein; putative integrase (fragment); N-terminal part of YdzT; defective prophage 3" /db_xref="PSEUDO:CAX52566.1" /translation="MELSYLLGIDPLTKKRLEISKGRFKTKKEAPVAARHVELQNDNG TFIKESDMPFKTFAKGWLKIYNRSGVKISSVRASEKKMMHFIAVLGQYPISKTQKNV* " gene complement(652713..653018) /gene="ydzTn" /locus_tag="BSU_06038" /old_locus_tag="BSU06038" /pseudo CDS 653432..653812 /gene="ydiM" /locus_tag="BSU_06040" /old_locus_tag="BSU06040" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein; prophage 3 region" /protein_id="NP_388485.1" /db_xref="EnsemblGenomes-Gn:BSU06040" /db_xref="EnsemblGenomes-Tr:CAB12423" /db_xref="SubtiList:BG12785" /db_xref="UniProtKB/Swiss-Prot:O34672" /translation="MLSDNNFVSETLENVQYLLPGAKVIKLRGYSRAHKVYTIAKSPV EKWKVAAGLSGSEIAILIRKGHWIGASIPAGGIVIDIDDSKQGELVKGLLDAQNFHCH CIRTLMGGSLFLRITNMGKRKLNK*" gene 653432..653812 /gene="ydiM" /locus_tag="BSU_06040" /old_locus_tag="BSU06040" S_feature 653813..654070 /Source="Nicolas_S_feature" /locus_tag="new_653813_654070" /HighExp="H2O2, dia15, S1, Heat, G150, Diami, G135, G180, S2, Etha" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.1454" /TUshortSig="SigA" /TUshortPSig="0.999" /TUlongSig="Sig-" /TUlongPSig="0.238" /label="S211" CDS 654071..654343 /gene="ydzU" /locus_tag="BSU_06048" /old_locus_tag="BSU06048" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein; prophage 3 region" /protein_id="YP_003097688.1" /db_xref="EnsemblGenomes-Gn:BSU06048" /db_xref="EnsemblGenomes-Tr:CAX52567" /db_xref="UniProtKB/Swiss-Prot:C0H3W7" /translation="MKAWKVEPYEISKAMELIYKYLLLDKKDFSLEEFYKLTIYAIKW KLEQAQFPLYLESTKKSHQNVIPQPFKIKGNVLYKTVIKNSGDFEE*" gene 654071..654343 /gene="ydzU" /locus_tag="BSU_06048" /old_locus_tag="BSU06048" CDS 654333..654692 /gene="ydzV" /locus_tag="BSU_06049" /old_locus_tag="BSU06049" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function; Product type h : extrachromosomal origin" /pseudo /codon_start=1 /transl_table=11 /product="conserved hypothetical protein; phage terminase (fragment); defective prophage 3" /db_xref="PSEUDO:CAX52568.1" /translation="MKNSSSWRVGVIHPFKKLSNIERNSVHYELASNDNGREKKDIVP ASVISPSGSCFSLADNGLVEKEGQKMKLTERQRRFCDFFTETRNTTEATRLAGNKGKN LNRVASQNLSKLDIQTI*" gene 654333..654692 /gene="ydzV" /locus_tag="BSU_06049" /old_locus_tag="BSU06049" /pseudo S_feature 654693..655136 /Source="Nicolas_S_feature" /locus_tag="new_654693_655136" /HighExp="H2O2, dia15, S1, G180, G135, G150, Heat, Diami, S2, Etha" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.999" /TUlongSig="Sig-" /TUlongPSig="0.238" /label="S212" CDS 654978..655193 /gene="ydiN" /locus_tag="BSU_06050" /old_locus_tag="BSU06050" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /pseudo /codon_start=1 /transl_table=11 /product="putative N-terminus of restriction enzyme; defective prophage 3" /db_xref="PSEUDO:SOX90546.1" /translation="MIKFSVILGMIRCSLTHITTKNTVNALKRMIYPKQKPSFFHEFK VLYKLLKKFCIKGIMIKNIRSCMGYFL*" gene 654978..655193 /gene="ydiN" /locus_tag="BSU_06050" /old_locus_tag="BSU06050" /pseudo promotor_-35 655123..655129 /Source="Nicolas_upshift_promotors" /id="U469" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.428571428571429" /psig="0.997002997002997" /xcortree=1874 /SigmaFactorBS="agcaaaaaccttcattctttcatgaatttaaagtattatata agcTACTGAAaaagttttgtataAAAGGTATAATGATAAAGAAcattcgttcttgtat g" /listShort="S213, ydiO, ydiP" /GFF_Attribute="listLong" /label="promotor_-35" S_feature 655138..655222 /Source="Nicolas_S_feature" /locus_tag="new_655138_655222" /HighExp="Diami, H2O2, dia5, dia15, Salt, M40t45, G180, G150, G135, M40t90" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="0.997, 0.999" /TUlongSig="Sig-" /TUlongPSig="0.238" /label="S213" upshifts 655138 /Source="Nicolas_upshifts" /id="U469" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.428571428571429" /psig="0.997002997002997" /xcortree=1874 /SigmaFactorBS="agcaaaaaccttcattctttcatgaatttaaagtattatata agcTACTGAAaaagttttgtataAAAGGTATAATGATAAAGAAcattcgttcttgtat g" /listShort="S213, ydiO, ydiP" /GFF_Attribute="listLong" promotor_-10 655143..655162 /Source="Nicolas_upshift_promotors" /id="U469" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.428571428571429" /psig="0.997002997002997" /xcortree=1874 /SigmaFactorBS="agcaaaaaccttcattctttcatgaatttaaagtattatata agcTACTGAAaaagttttgtataAAAGGTATAATGATAAAGAAcattcgttcttgtat g" /listShort="S213, ydiO, ydiP" /GFF_Attribute="listLong" /label="promotor_-10" CDS 655223..656506 /gene="bsuMA" /locus_tag="BSU_06060" /old_locus_tag="BSU06060" /EC_number="2.1.1.37" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:11751814, 12682299, 16014871, 16267290" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11751814, 12682299, 16014871, 16267290; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="DNA-methyltransferase (cytosine-specific); prophage 3 region" /protein_id="NP_388487.1" /db_xref="EnsemblGenomes-Gn:BSU06060" /db_xref="EnsemblGenomes-Tr:CAB12425" /db_xref="GOA:O34939" /db_xref="InterPro:IPR001525" /db_xref="InterPro:IPR029063" /db_xref="SubtiList:BG12787" /db_xref="UniProtKB/Swiss-Prot:O34939" /translation="MTNFILNENKQLSLAIEDENIENFYIDGTDLVRKIIRRSGSGVT SRVPVLSTQDLENKNLHELYDESWLRMKNRPNTELTTESINIADLFSGCGGLSLGVWE ACRALGINPRFSFACDLNEAALSVYEKNFSPDFSLNESIEKHINGELGAPLTVEEQRI KDKVKKIDFILAGPPCQGHSDLNNHTRRKDPRNALLMRVSRVIELFQPSSVLVENVPG IIHDKSGSFKEFKNHLKTQGYYFDEIVLNAEKLGVSQARRRYFIFASKTPVSSLNQIN EFYSTNSRPISWAISDLVENVGDDIFNTASEHSLENKRRIEYLFENNLFELPNSERPD CHRLKPHSYKSVYGRMYWDRPAPTITRGFGSTGQGRFVHSLLKRTITPHEAARIQFFP DFFNFGDLRRRQYQDVIGNAVPSKLSYLLALHQLR*" gene 655223..656506 /gene="bsuMA" /locus_tag="BSU_06060" /old_locus_tag="BSU06060" CDS 656528..657697 /gene="bsuMB" /locus_tag="BSU_06070" /old_locus_tag="BSU06070" /EC_number="2.1.1.37" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:11751814, 16267290" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11751814, 16267290; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="DNA-methyltransferase (cytosine-specific); defective prophage 3" /protein_id="NP_388488.1" /db_xref="EnsemblGenomes-Gn:BSU06070" /db_xref="EnsemblGenomes-Tr:CAB12426" /db_xref="GOA:O34680" /db_xref="InterPro:IPR001525" /db_xref="InterPro:IPR018117" /db_xref="InterPro:IPR029063" /db_xref="InterPro:IPR031303" /db_xref="SubtiList:BG12788" /db_xref="UniProtKB/Swiss-Prot:O34680" /translation="MKVVSLFSGIGGIELGLHQSGHTTEIFCEVDPLAKAVLSKNFPG VKIEDDINEIRELPSCDLVAAGFPCQDLSQAGGKEGIDGSRSGLVKKLFELIEKKEHA NRPPWILIENVPYMLRLNRGKAMSYLTSVLSELGYTWAYRTVDARCFGLPQRRHRVIL LASLFEDPKDVIFSQDHSEPDLDGKPSVVDHSNYYGFYWTEGLRGVGWAREAVPPIKC GSSVGIASPPAVWSPYEDIVGTINIRDAERLQGFPEDWTNITTETGKDIKEGARWRLV GNAVSVRVSKWIGENLSQPKGSISDFEGELVTKTWPSAAWGYGDKKYKVPVSKWVANT EQIAISEFLNHPLKPLSARALNGFLGRAARCTNVNYSDEFINSLERCKDRQLQKV*" gene 656528..657697 /gene="bsuMB" /locus_tag="BSU_06070" /old_locus_tag="BSU06070" downshifts 657703 /Source="Nicolas_upshifts" /id="D293" /incds=0 /nref=237 /ntot=257 /MaxReadThrough="2.10319" /MaxDrop="7.17612" /score="34.7238204" /energy="-15.1" /TU="NA" /idTUdmin="U468" /TUdmin=0 /isTUend="TRUE" downshifts complement(657777) /Source="Nicolas_upshifts" /id="D294" /incds=0 /nref=26 /ntot=183 /MaxReadThrough="2.48582" /MaxDrop="4.12737" /score="11.0887998" /energy="-15.6" /TU="NA" /idTUdmin="U471" /TUdmin=2 /isTUend="TRUE" CDS complement(657793..658062) /gene="ydzWc" /locus_tag="BSU_06073" /old_locus_tag="BSU06073" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function; Product type e : enzyme" /pseudo /codon_start=1 /transl_table=11 /product="putative phosphoglucomutase; C-terminal part of YdzW; defective prophage 3" /db_xref="PSEUDO:CAX52569.1" /translation="MNLASFGSVKVTTVEDYLTGIERLWKALRNSWAFHSQMFLNVFL KSDPWMCLRLSGTEPKIKFYFRVDESLAETRNPQRIEKEFMELVE*" gene complement(657793..658062) /gene="ydzWc" /locus_tag="BSU_06073" /old_locus_tag="BSU06073" /pseudo CDS complement(658019..658189) /gene="ydzWmc" /locus_tag="BSU_06074" /old_locus_tag="BSU06074" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function; Product type e : enzyme" /pseudo /codon_start=1 /transl_table=11 /product="putative phosphoglucomutase; internal part of YdzW" /translation="MSLYEALLSIEEYGYFQEGLRSLTLKGKEGAELIQQTLAAFRSE FGQLWFRQGYHC*" gene complement(658019..658189) /gene="ydzWmc" /locus_tag="BSU_06074" /old_locus_tag="BSU06074" /pseudo CDS complement(658120..658605) /gene="ydzWmb" /locus_tag="BSU_06076" /old_locus_tag="BSU06076" /EC_number="5.4.2.-" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function; Product type e : enzyme" /pseudo /codon_start=1 /transl_table=11 /product="putative phosphoglucomutase; internal part of YdzW" /translation="LIATDPDADRLGIAVKNENGEYTVLTGNQTEPLLLHYILTQIKK KGTLPSNGIVLKTIVTSELGREVATSFRVETIGVLTGFKFIARKINGYYKTGEHNFLF GYEESYGYLIGDFVRDKDAVQTDVLAVEVCAYYKKKGFHYTKLSLVLKNMATFRKACA H*" gene complement(658120..658605) /gene="ydzWmb" /locus_tag="BSU_06076" /old_locus_tag="BSU06076" /pseudo promotor_-35 658470..658473 /Source="Nicolas_upshift_promotors" /id="U470" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.563436563436563" /psig="0.997002997002997" /xcortree=3091 /SigmaFactorBS="aatcgttttaagaacgatcccattagatggaagtgttcCTTT cttttttatttgggTTAAGATATAGTGGAGCAGAagtggctcggtttgatttccggtt a" /listShort="S214" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 658488..658507 /Source="Nicolas_upshift_promotors" /id="U470" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.563436563436563" /psig="0.997002997002997" /xcortree=3091 /SigmaFactorBS="aatcgttttaagaacgatcccattagatggaagtgttcCTTT cttttttatttgggTTAAGATATAGTGGAGCAGAagtggctcggtttgatttccggtt a" /listShort="S214" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 658492 /Source="Nicolas_upshifts" /id="U470" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.563436563436563" /psig="0.997002997002997" /xcortree=3091 /SigmaFactorBS="aatcgttttaagaacgatcccattagatggaagtgttcCTTT cttttttatttgggTTAAGATATAGTGGAGCAGAagtggctcggtttgatttccggtt a" /listShort="S214" /GFF_Attribute="listLong" S_feature 658495..658899 /Source="Nicolas_S_feature" /locus_tag="new_658495_658899" /HighExp="Cold, LoTm, C30, T0.30H, HPh, Gly, S0, LPh, UNK1, T1.0H" /AntisenseName="ydzW" /AntisenseCor="0.298083403528066" /AntisenseRegPval="-6.2" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.997" /TUlongSig="NA" /TUlongPSig="NA" /label="S214" CDS complement(658615..658758) /gene="ydzW" /locus_tag="BSU_06077" /old_locus_tag="BSU06077" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function; Product type e : enzyme" /pseudo /codon_start=1 /transl_table=11 /product="putative phosphomannomutase; internal part of YdzW" /db_xref="PSEUDO:CAX52572.1" /translation="MALAAMNYKHVAVGKEQEQPALCFPLSPVQMLKNMPRLSWPSGK AAN*" gene complement(658615..658758) /gene="ydzW" /locus_tag="BSU_06077" /old_locus_tag="BSU06077" /pseudo CDS complement(658813..659010) /gene="ydzW" /locus_tag="BSU_06078" /old_locus_tag="BSU06078" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function; Product type e : enzyme" /pseudo /codon_start=1 /transl_table=11 /product="putative phosphoglucomutase; internal part of YdzW" /translation="FAVRHLHGFAGIVVTASHNPPEYNGYKVYGPDGGQLPPSKGPDQ NIAQRWTRHTLNYFRKLKYLR*" gene complement(658813..659010) /gene="ydzW" /locus_tag="BSU_06078" /old_locus_tag="BSU06078" /pseudo CDS complement(658968..659129) /gene="ydzWma" /locus_tag="BSU_06079" /old_locus_tag="BSU06079" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function; Product type e : enzyme" /pseudo /codon_start=1 /transl_table=11 /product="putative phosphomannomutase; internal part of YdzW" /translation="DIYTLRKVSAGLAAFIMEAARTLASSAYVFESLRPTTVLSLQYV TFMVLPVLL*" gene complement(658968..659129) /gene="ydzWma" /locus_tag="BSU_06079" /old_locus_tag="BSU06079" /pseudo CDS complement(659114..659221) /gene="ydzWn" /locus_tag="BSU_06083" /old_locus_tag="BSU06083" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function; Product type e : enzyme" /pseudo /codon_start=1 /transl_table=11 /product="putative phosphomannomutase; N-terminal part of YdzW; defective prophage 3" /translation="MRKTWKMLFIRNLGYGTGGMRGEIGAGTNRMTSIR*" gene complement(659114..659221) /gene="ydzWn" /locus_tag="BSU_06083" /old_locus_tag="BSU06083" /pseudo S_feature complement(659222..659341) /Source="Nicolas_S_feature" /locus_tag="new_659222_659341_c" /HighExp="LoTm, T4.0H, BC, T5.0H, M9-stat, T3.30H, S2, T3.0H, Sw, B60" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="0.993, 0.977" /TUlongSig="NA" /TUlongPSig="NA" /label="S215" promotor_-10 complement(659332..659351) /Source="Nicolas_upshift_promotors" /id="U471" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.321678321678322" /psig="0.993006993006993" /xcortree=2932 /SigmaFactorBS="caagagcactcgatttatgtcagaaagtcgtCGTTcgaaaac ctctagacTATATTATAATGAACAATAAtgttattttattgtaggtcaatcataggct g" /listShort="S215, ydzW, ydzW, ydzW, ydzW, ydzW, ydzW, ydzW" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(659341) /Source="Nicolas_upshifts" /id="U471" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.321678321678322" /psig="0.993006993006993" /xcortree=2932 /SigmaFactorBS="caagagcactcgatttatgtcagaaagtcgtCGTTcgaaaac ctctagacTATATTATAATGAACAATAAtgttattttattgtaggtcaatcataggct g" /listShort="S215, ydzW, ydzW, ydzW, ydzW, ydzW, ydzW, ydzW" /GFF_Attribute="listLong" S_feature complement(659343..659558) /Source="Nicolas_S_feature" /locus_tag="new_659343_659558_c" /HighExp="LBGstat, T0.30H, M9-stat, T1.0H, T1.30H, Lbtran, T2.0H, LBGtran, T2.30H, Diami" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.11296" /TUshortSig="SigA" /TUshortPSig="0.977" /TUlongSig="NA" /TUlongPSig="NA" /label="S216" promotor_-35 complement(659367..659370) /Source="Nicolas_upshift_promotors" /id="U471" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.321678321678322" /psig="0.993006993006993" /xcortree=2932 /SigmaFactorBS="caagagcactcgatttatgtcagaaagtcgtCGTTcgaaaac ctctagacTATATTATAATGAACAATAAtgttattttattgtaggtcaatcataggct g" /listShort="S215, ydzW, ydzW, ydzW, ydzW, ydzW, ydzW, ydzW" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 659535..659541 /Source="Nicolas_upshift_promotors" /id="U473" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.857142857142857" /psig=1 /xcortree=2344 /SigmaFactorBS="taccaattcgatatttgaattggtctctcaaacaaTTCCATC ctctttatttatTATGATACAATTATATTAATtagaaaatacatacatattagcttgt g" /listShort="ydiR, ydiS, ydjA, S217, S218, ydjB, S219, ydjC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(659544..659563) /Source="Nicolas_upshift_promotors" /id="U472" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.458541458541459" /psig="0.977022977022977" /xcortree=3186 /SigmaFactorBS="tttacccccataaaatcacacaagctaatatgtatgtATTTt ctaattaatataaTTGTATCATAATAAATAAAGaggatggaattgtttgagagaccaa t" /listShort="S216, S215, ydzW, ydzW, ydzW, ydzW, ydzW, ydzW" /listLong="ydzW" /label="promotor_-10" promotor_-10 659554..659573 /Source="Nicolas_upshift_promotors" /id="U473" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.857142857142857" /psig=1 /xcortree=2344 /SigmaFactorBS="taccaattcgatatttgaattggtctctcaaacaaTTCCATC ctctttatttatTATGATACAATTATATTAATtagaaaatacatacatattagcttgt g" /listShort="ydiR, ydiS, ydjA, S217, S218, ydjB, S219, ydjC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(659558) /Source="Nicolas_upshifts" /id="U472" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.458541458541459" /psig="0.977022977022977" /xcortree=3186 /SigmaFactorBS="tttacccccataaaatcacacaagctaatatgtatgtATTTt ctaattaatataaTTGTATCATAATAAATAAAGaggatggaattgtttgagagaccaa t" /listShort="S216, S215, ydzW, ydzW, ydzW, ydzW, ydzW, ydzW" /listLong="ydzW" upshifts 659560 /Source="Nicolas_upshifts" /id="U473" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.857142857142857" /psig=1 /xcortree=2344 /SigmaFactorBS="taccaattcgatatttgaattggtctctcaaacaaTTCCATC ctctttatttatTATGATACAATTATATTAATtagaaaatacatacatattagcttgt g" /listShort="ydiR, ydiS, ydjA, S217, S218, ydjB, S219, ydjC" /GFF_Attribute="listLong" promotor_-35 complement(659578..659581) /Source="Nicolas_upshift_promotors" /id="U472" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.458541458541459" /psig="0.977022977022977" /xcortree=3186 /SigmaFactorBS="tttacccccataaaatcacacaagctaatatgtatgtATTTt ctaattaatataaTTGTATCATAATAAATAAAGaggatggaattgtttgagagaccaa t" /listShort="S216, S215, ydzW, ydzW, ydzW, ydzW, ydzW, ydzW" /listLong="ydzW" /label="promotor_-35" CDS 659623..660564 /gene="bsuRA" /locus_tag="BSU_06090" /old_locus_tag="BSU06090" /EC_number="3.1.21.4" /function="16.8: Protect" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:11751814, 15728999" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11751814, 15728999; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="type-2 restriction enzyme BsuMI component BsuRA (YdiR); prophage region 3" /protein_id="NP_388490.1" /db_xref="EnsemblGenomes-Gn:BSU06090" /db_xref="EnsemblGenomes-Tr:CAB12428" /db_xref="GOA:O35025" /db_xref="SubtiList:BG12790" /db_xref="UniProtKB/Swiss-Prot:O35025" /translation="MTFIKRLEDAYETLLGNYPAGVSSTSTSKYNEIRKIVSEAFLIG ENEVYVTGTSRRISNLDTRFAQGNQRNKHTRMAVAFISIPSVDDSELDELIIRTRNSA ITTSSKFCNGEERGTIFDGILLFLVFEGETKVYPLAFLVFENDFELKEKAEELIPGIE LKEYPRANQSPAQENNKSAKNEDEESAKSYVVFLDIEEDGSIVEFVEDKDKTYRIGDM IWTASHTNGSSAITRRLEVIEVVENLVVCKIKHKYNEPVDKNSLLKFVNIEQDLISFL DLHPNVQNGSEGFVSGDIVDENATTSSDDLPEDFENN*" gene 659623..660564 /gene="bsuRA" /locus_tag="BSU_06090" /old_locus_tag="BSU06090" CDS 660596..661627 /gene="bsuRB" /locus_tag="BSU_06100" /old_locus_tag="BSU06100" /EC_number="3.1.21.4" /function="16.8: Protect" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:11751814" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11751814; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="type-2 restriction enzyme BsuMI component BsuRB (YdiS); prophage region 3" /protein_id="NP_388491.1" /db_xref="EnsemblGenomes-Gn:BSU06100" /db_xref="EnsemblGenomes-Tr:CAB12429" /db_xref="GOA:O34885" /db_xref="InterPro:IPR011704" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG12791" /db_xref="UniProtKB/Swiss-Prot:O34885" /translation="MEISKQTSDLLLSLEKKKGTLPKFSVLRSIPRNRIIYGAPGTGK SNYLEREVGKIFGDNPYVFTRVTFFPGYTYGQFIGAYKPVPIYKKLSGEEEIFSSNFR DKMENFEPMIDYQFVPGPFIDVLIKALKNRYTNFILIIEEINRANAASVFGDIFQLLD RNKNGESDYPVTFGPDIMNYLARNGIKDEMIKLPSNFFIWATMNNADQGVLPLDTAFK RRWSFEYLELEKYRKAVDSWKLSLRYKGHNKVIMWNDFRDIINKRLKGKVPEDKLLGP FFLKESELWNQNVFKNKLLYYLKEDVFKHNPTIDFLNASTFSELIEKYDGSDNIFTFD IDDSSFVSD*" gene 660596..661627 /gene="bsuRB" /locus_tag="BSU_06100" /old_locus_tag="BSU06100" CDS 661630..663027 /gene="bsuRC" /locus_tag="BSU_06110" /old_locus_tag="BSU06110" /EC_number="3.1.21.4" /function="16.5: Explore" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:11751814" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11751814; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="type-2 restriction enzyme BsuMI component BsuRC (YdjA); prophage region 3" /protein_id="NP_388492.1" /db_xref="EnsemblGenomes-Gn:BSU06110" /db_xref="EnsemblGenomes-Tr:CAB12430" /db_xref="GOA:O34303" /db_xref="InterPro:IPR018579" /db_xref="SubtiList:BG12792" /db_xref="UniProtKB/Swiss-Prot:O34303" /translation="MDKSSKFFFEDQKYNKERIVRVLGGNLALLKSKGILYEDSSGDL IFNYVGVISNGRNVIFILPKYCNRHLDEHSKRTLFNKLLKIFKKYSGLNKSRESDYFV SELDSDEVSDFMIADYLLNDFSLNGYYQKKFTEYEIDGEGIIDWSKTVNEITPVFSKG VPYYFSTYNEVVQKDEYHLIVKIHKWALSKYFNDFGVILGFTGLEFDKSCDGMKILDY ADFFGSVINKEIVNTYVDRDVKLLKALKTAIDREENQFSKRPTLSLYGTKYFHRVWEE VCKTVFSHVNEYVKKISRPNWINFTDIEVNKEKKTLEPDIIKAFEYRSKEYFLILDAK YYNINFDGKKLEGNPGVEDITKQLLYDKALEKLSRGKTKHNAFLFPSSNSTNTFKVFG SVDFDFLDIAAVTLVYISAEQVYNLYLENKTFSTDDLFKFVSEINKSKKRHSVITSTL YGNMFLFTKRLSDKN*" gene 661630..663027 /gene="bsuRC" /locus_tag="BSU_06110" /old_locus_tag="BSU06110" S_feature 663028..663224 /Source="Nicolas_S_feature" /locus_tag="new_663028_663224" /HighExp="Lbtran, C90, M40t45, HPh, M0t45, LBGtran, aero, Lbstat, BI, Mt0" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S217" downshifts 663181 /Source="Nicolas_upshifts" /id="D295" /incds=0 /nref=3 /ntot=131 /MaxReadThrough="5.36465" /MaxDrop="3.0162" /score="7.16368756" /energy="-18.1" /TU="U473" /idTUdmin="U473" /TUdmin="-1364" /isTUend="FALSE" downshifts 663243 /Source="Nicolas_upshifts" /id="D296" /incds=0 /nref=5 /ntot=69 /MaxReadThrough="4.58628" /MaxDrop="3.49698" /score="7.16368756" /energy="-18.1" /TU="U473" /idTUdmin="U473" /TUdmin="-1302" /isTUend="FALSE" S_feature 663288..663600 /Source="Nicolas_S_feature" /locus_tag="new_663288_663600" /HighExp="dia15, Diami, H2O2, Paraq, dia5, LBGstat, G180, Oxctl, LBGexp, HPh" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S218" CDS 663601..663936 /gene="ydjB" /locus_tag="BSU_06120" /old_locus_tag="BSU06120" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein; prophage region 3" /protein_id="NP_388493.1" /db_xref="EnsemblGenomes-Gn:BSU06120" /db_xref="EnsemblGenomes-Tr:CAB12431" /db_xref="SubtiList:BG12793" /db_xref="UniProtKB/Swiss-Prot:O34778" /translation="MLNIKSDRIMTSDPQKFTVDGVRFFQQYLNKIRPDAMEIDNLII NSDIIKEDLIVHVSKMIDRLALYDLHRKRSIDKHFSAAFTVDINDREEFYSANIADVS IDLNESSGV*" gene 663601..663936 /gene="ydjB" /locus_tag="BSU_06120" /old_locus_tag="BSU06120" S_feature 663937..664318 /Source="Nicolas_S_feature" /locus_tag="new_663937_664318" /HighExp="H2O2, dia15, G135, Paraq, G180, G150, Diami, Oxctl, LBGexp, HPh" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S219" CDS 664319..664669 /gene="ydjC" /locus_tag="BSU_06130" /old_locus_tag="BSU06130" /function="18: Unknown function" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein; prophage region 3" /protein_id="NP_388494.1" /db_xref="EnsemblGenomes-Gn:BSU06130" /db_xref="EnsemblGenomes-Tr:CAB12432" /db_xref="InterPro:IPR029058" /db_xref="SubtiList:BG12794" /db_xref="UniProtKB/Swiss-Prot:O34715" /translation="MVSIFYANRLSYSIWNTIPGKYIREELEQNGVTYNELIKYWDIT DPSQALPKVNKDNVLLISAKHDQYIDLKDADYLWESWGRPTRYVYNCGHSGIVLCRKK LANDTLSFIREKLV*" gene 664319..664669 /gene="ydjC" /locus_tag="BSU_06130" /old_locus_tag="BSU06130" downshifts 664545 /Source="Nicolas_upshifts" /id="D297" /incds=1 /nref=1 /ntot=71 /MaxReadThrough="1.89703" /MaxDrop="2.58458" /score="-4.72838456" /energy="-13.9" /TU="NA" /idTUdmin="U473" /TUdmin=0 /isTUend="TRUE" CDS complement(664775..667264) /gene="gutR" /locus_tag="BSU_06140" /old_locus_tag="BSU06140" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:11118449, 11390381, 12897001" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11118449, 11390381, 12897001; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator of the glucitol operon" /protein_id="NP_388495.1" /db_xref="EnsemblGenomes-Gn:BSU06140" /db_xref="EnsemblGenomes-Tr:CAB12433" /db_xref="GOA:P39143" /db_xref="InterPro:IPR002182" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR011990" /db_xref="InterPro:IPR013026" /db_xref="InterPro:IPR019734" /db_xref="InterPro:IPR024123" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG10178" /db_xref="UniProtKB/Swiss-Prot:P39143" /translation="MAELENRKQFAQMLAPGVKTLKLHPDYKVRRKKNEKTGQSYIDK IALQLGVSPNTIKSWIGQMGANYIPGRIDDGKLFGMIWIILEKTDLDIEWLTDLLEAT TIPVIKPALPVWAASCLKKAKILRKDGLFGAPSEGEIENVVKRLFHDRPGQETNALTE QPITHNLPSRWSGRFIGRSFDMEAIRQWMLSPSPVCLITGWAGMGKTTIALEAAYSCV DDTSVWPAFNSIIWVSADWKGLSFSDFLNTIAYQLGRKEQIDKSINVKRFVVRNALAN YTREKPILLIVDSIDTAERDIHEFITSLPQGVKVLLTARENVKQTYRESFGEMTAIQL SGLDQTDAHEFFQQEVHHCLQTCNLPRKREKLEQLLHLSSDLKNEFISATAGNPKAMA LSIAYMSDDDIPAQQLIHELGKAGYSLLELFEFLFGRTWDRCNEDTRKLWQTLCFFSK PPDEKSLAAAAGLDARRFHYAMEQMRSYALIQPERSQGRTQYLAHQTVVAYGEQHLSE QHEYEKEARNRWAHYYIDYAETHLKREQPNSIYWSYLLGRNLDQMKQEWPNILKVIQW ASETEQKEILIELITRISHFLSRINLPLRIEYGRKAADAAHHLGQHTREAYFRIDTSG WALMEVNDLDGALQQIEAGLKILEQSDAHDAYDLKVWGHALKARLFLKDGQQEKAETI LNEIENQPISPTIQHRVLLVRGDLSFARGYHVEAIQLYEAANEISSTYGGEKTIEAYF NLGVAYVKCDQFEKAEEAFEQMLYDKHNANQVELIYYHYGMAQLLYRKGEKTKAVESN QKAIRLIDSWEPAIGIRGEVERLARATKENE*" gene complement(664775..667264) /gene="gutR" /locus_tag="BSU_06140" /old_locus_tag="BSU06140" downshifts complement(664797) /Source="Nicolas_upshifts" /id="D298" /incds=0 /nref=56 /ntot=209 /MaxReadThrough="0.69715" /MaxDrop="4.256" /score="0.285109352" /energy="-13.9" /TU="NA" /idTUdmin="U474" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(667278..667297) /Source="Nicolas_upshift_promotors" /id="U474" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.573426573426573" /psig="0.995004995004995" /xcortree=2305 /SigmaFactorBS="ctttcctgctgtataaaaggacagcggcactgtacttttatt ttttCATATACAaaaaacgctggatTGATAAAATAGTACTAATAGgaggtgcaggctt a" /listShort="gutR" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(667304) /Source="Nicolas_upshifts" /id="U474" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.573426573426573" /psig="0.995004995004995" /xcortree=2305 /SigmaFactorBS="ctttcctgctgtataaaaggacagcggcactgtacttttatt ttttCATATACAaaaaacgctggatTGATAAAATAGTACTAATAGgaggtgcaggctt a" /listShort="gutR" /GFF_Attribute="listLong" promotor_-35 complement(667311..667318) /Source="Nicolas_upshift_promotors" /id="U474" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.573426573426573" /psig="0.995004995004995" /xcortree=2305 /SigmaFactorBS="ctttcctgctgtataaaaggacagcggcactgtacttttatt ttttCATATACAaaaaacgctggatTGATAAAATAGTACTAATAGgaggtgcaggctt a" /listShort="gutR" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 667367..667368 /Source="Nicolas_upshift_promotors" /id="U475" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.481518481518482" /psig="0.848151848151848" /xcortree=335 /SigmaFactorBS="aataaaagtacagtgccgctgtccttttatacagcaggaaag gcTGttgaacgtgttaaaaAGCAGATAAAATGGGGGCAGtaacagagaaaacaaaaat g" /listShort="S220, gutB, gutP, ydjE" /GFF_Attribute="listLong" /label="promotor_-35" S_feature 667383..667465 /Source="Nicolas_S_feature" /locus_tag="new_667383_667465" /HighExp="Lbstat, BI, M40t90, Mt0, M0t90, dia5, dia0, Lbexp, Lbtran, LBGtran" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.848" /TUlongSig="NA" /TUlongPSig="NA" /label="S220" upshifts 667383 /Source="Nicolas_upshifts" /id="U475" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.481518481518482" /psig="0.848151848151848" /xcortree=335 /SigmaFactorBS="aataaaagtacagtgccgctgtccttttatacagcaggaaag gcTGttgaacgtgttaaaaAGCAGATAAAATGGGGGCAGtaacagagaaaacaaaaat g" /listShort="S220, gutB, gutP, ydjE" /GFF_Attribute="listLong" promotor_-10 667384..667403 /Source="Nicolas_upshift_promotors" /id="U475" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.481518481518482" /psig="0.848151848151848" /xcortree=335 /SigmaFactorBS="aataaaagtacagtgccgctgtccttttatacagcaggaaag gcTGttgaacgtgttaaaaAGCAGATAAAATGGGGGCAGtaacagagaaaacaaaaat g" /listShort="S220, gutB, gutP, ydjE" /GFF_Attribute="listLong" /label="promotor_-10" CDS 667466..668527 /gene="gutB" /locus_tag="BSU_06150" /old_locus_tag="BSU06150" /EC_number="1.1.1.14" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:1460002, 8195086, 8195087, 12897001, 19784641" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1460002, 8195086, 8195087, 12897001, 19784641; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="glucitol (sorbitol) dehydrogenase" /protein_id="NP_388496.1" /db_xref="EnsemblGenomes-Gn:BSU06150" /db_xref="EnsemblGenomes-Tr:CAB12434" /db_xref="GOA:Q06004" /db_xref="InterPro:IPR002328" /db_xref="InterPro:IPR011032" /db_xref="InterPro:IPR013149" /db_xref="InterPro:IPR013154" /db_xref="InterPro:IPR020843" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG10177" /db_xref="UniProtKB/Swiss-Prot:Q06004" /translation="MTHTVPQNMKAAVMHNTREIKIETLPVPDINHDEVLIKVMAVGI CGSDLHYYTNGRIGNYVVEKPFILGHECAGEIAAVGSSVDQFKVGDRVAVEPGVTCGR CEACKEGRYNLCPDVQFLATPPVDGAFVQYIKMRQDFVFLIPDSLSYEEAALIEPFSV GIHAAARTKLQPGSTIAIMGMGPVGLMAVAAAKAFGAGTIIVTDLEPLRLEAAKKMGA THIINIREQDALEEIKTITNDRGVDVAWETAGNPAALQSALASVRRGGKLAIVGLPSQ NEIPLNVPFIADNEIDIYGIFRYANTYPKGIEFLASGIVDTKHLVTDQYSLEQTQDAM ERALQFKNECLKVMVYPNR*" gene 667466..668527 /gene="gutB" /locus_tag="BSU_06150" /old_locus_tag="BSU06150" CDS 668601..669992 /gene="gutP" /locus_tag="BSU_06160" /old_locus_tag="BSU06160" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2b: Function from indirect experimental evidences (e.g. phenotypes); PubMedId: 12897001, 22720735; Product type t: transporter" /codon_start=1 /transl_table=11 /product="H+-glucitol symporter; prophage region 3" /protein_id="NP_388497.1" /db_xref="EnsemblGenomes-Gn:BSU06160" /db_xref="EnsemblGenomes-Tr:CAB12435" /db_xref="GOA:O34368" /db_xref="InterPro:IPR001927" /db_xref="InterPro:IPR018043" /db_xref="InterPro:IPR020846" /db_xref="InterPro:IPR036259" /db_xref="SubtiList:BG12795" /db_xref="UniProtKB/Swiss-Prot:O34368" /translation="MIGTEKVTALKAKHQSKSSTGLSWFERIGYGFGDMSYNIIFQFV NAYLLFYYTDVGGIQPAVIATLFLVVRVLDAIFDPIMGLILDKTNTRWGKARPYLLWV AFPFALFTFLCFTTPHFGETGNMVYAYVTYILLGMSFSMQTIPVNSLTGRMTNSVEER TVLTTTRMILVYIGILLSISCATPLATAIGGEDQAFGFQMTALIYAAVSIVLNLFSFF TVRERIQPKKRKKQGIKKTLSVLFKNKPLLMLISSFLAFAIGFNIKLSTMVYYFTYNV NHKEFVFMGTVLFFGAALISNLFIPFFSEKWGRKQVMIITAALSLISYAGLHFTPYSS IPLIFIWLFASGFFTTPLNTLAWGMVADCVDYAEWKTGIRADGVVISSMSFINKLGVA LAGSFSAIYLGIAGYVANTDQTVASLNAIKNMNALIPGFFILLSIILIAFYPLTEKRY KHIISELEQRSAR*" gene 668601..669992 /gene="gutP" /locus_tag="BSU_06160" /old_locus_tag="BSU06160" promotor_-35 670019..670026 /Source="Nicolas_upshift_promotors" /id="U476" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.871128871128871" /psig="0.997002997002997" /xcortree=489 /SigmaFactorBS="cgagataaatagatgtaaaatttttaatattcaaTGTTGTAT ttatggcaaaaagTAATATACTGAGACTGTAATctagactttataaatgagtgtgata a" /listShort="ydjE" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 670040..670059 /Source="Nicolas_upshift_promotors" /id="U476" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.871128871128871" /psig="0.997002997002997" /xcortree=489 /SigmaFactorBS="cgagataaatagatgtaaaatttttaatattcaaTGTTGTAT ttatggcaaaaagTAATATACTGAGACTGTAATctagactttataaatgagtgtgata a" /listShort="ydjE" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 670045 /Source="Nicolas_upshifts" /id="U476" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.871128871128871" /psig="0.997002997002997" /xcortree=489 /SigmaFactorBS="cgagataaatagatgtaaaatttttaatattcaaTGTTGTAT ttatggcaaaaagTAATATACTGAGACTGTAATctagactttataaatgagtgtgata a" /listShort="ydjE" /GFF_Attribute="listLong" CDS 670087..671049 /gene="ydjE" /locus_tag="BSU_06170" /old_locus_tag="BSU06170" /EC_number="2.7.1.-" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 26483775, 22720735; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative sugar kinase (ribokinase family); prophage region 3" /protein_id="NP_388498.1" /db_xref="EnsemblGenomes-Gn:BSU06170" /db_xref="EnsemblGenomes-Tr:CAB12436" /db_xref="GOA:O34768" /db_xref="InterPro:IPR002173" /db_xref="InterPro:IPR011611" /db_xref="InterPro:IPR029056" /db_xref="SubtiList:BG12796" /db_xref="UniProtKB/Swiss-Prot:O34768" /translation="MRSHSVVCIGELLIDFFCTDVDVDLMEGRQFLKSAGGAPANVSA AIAKLGGDAAFSGKVGKDPFGYFLKRTLDAVHVDTSMLVMDEKAPTTLAFVSLKQNGE RDFVFNRGADALFTLEDIDQEKLNEAKILHFGSATALLSDPFCSAYLRLMSIAKDNGQ FISFDPNYREDLWRGRVSEFVSVAKKAIAVSDFVKVSDEELEIISGVKDHEKGVAILH EIGANIVAVTLGKSGTLLSNGKDREIIPSIPVTSIDSTGAGDAFVGAALYQLANTDQI QSVDADFVKLREIVAFANKVGALVCTKIGAIDALPSLDEIGVSL*" gene 670087..671049 /gene="ydjE" /locus_tag="BSU_06170" /old_locus_tag="BSU06170" downshifts 671034 /Source="Nicolas_upshifts" /id="D299" /incds=0 /nref=86 /ntot=213 /MaxReadThrough="2.99546" /MaxDrop="4.52045" /score="16.4550614" /energy="-14" /TU="NA" /idTUdmin="U475" /TUdmin="-1" /isTUend="TRUE" promotor_-35 671174..671183 /Source="Nicolas_upshift_promotors" /id="U477" /multdbtbs="SigW" /comp="M9" /sig="SigWXY" /pcomp="0.996003996003996" /psig="0.996003996003996" /xcortree=1663 /SigmaFactorBS="agttgtatattttttgtttgaaatgtcattttttattaaaaa agTGAAACTTTTaacgataataaaTAGTATATGTAACAAGggttaccgaattagcttt a" /listShort="pspA, S221, ydjG, ydjH, ydjI" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 671190 /Source="Nicolas_upshifts" /id="U477" /multdbtbs="SigW" /comp="M9" /sig="SigWXY" /pcomp="0.996003996003996" /psig="0.996003996003996" /xcortree=1663 /SigmaFactorBS="agttgtatattttttgtttgaaatgtcattttttattaaaaa agTGAAACTTTTaacgataataaaTAGTATATGTAACAAGggttaccgaattagcttt a" /listShort="pspA, S221, ydjG, ydjH, ydjI" /GFF_Attribute="listLong" promotor_-10 671196..671211 /Source="Nicolas_upshift_promotors" /id="U477" /multdbtbs="SigW" /comp="M9" /sig="SigWXY" /pcomp="0.996003996003996" /psig="0.996003996003996" /xcortree=1663 /SigmaFactorBS="agttgtatattttttgtttgaaatgtcattttttattaaaaa agTGAAACTTTTaacgataataaaTAGTATATGTAACAAGggttaccgaattagcttt a" /listShort="pspA, S221, ydjG, ydjH, ydjI" /GFF_Attribute="listLong" /label="promotor_-10" CDS 671245..671928 /gene="pspA" /locus_tag="BSU_06180" /old_locus_tag="BSU06180" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:11454200" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11454200; Product type h: extrachromosomal origin" /codon_start=1 /transl_table=11 /product="phage shock protein A homolog regulator; prophage region 3" /protein_id="NP_388499.1" /db_xref="EnsemblGenomes-Gn:BSU06180" /db_xref="EnsemblGenomes-Tr:CAB12437" /db_xref="GOA:P54617" /db_xref="InterPro:IPR007157" /db_xref="SubtiList:BG12797" /db_xref="UniProtKB/Swiss-Prot:P54617" /translation="MSIIGRFKDIMSANINALLDKAENPEKMVDQYLRNMNSDLAKVK AETAAVMAEEQRAKREYHECQADMEKMESYAMKALQAGNESDARKFLERKTSLESKLS ELQAANQIAATNAAQMRKMHDKLVSDIGELEARKNMIKAKWAVAKTQERMNKLGASVS STSQSMSAFGRMEDKVNKALDQANAMAELNSAPQDDMADLSAKYDTGGSSQVDDELAA LKAKMMLDK*" gene 671245..671928 /gene="pspA" /locus_tag="BSU_06180" /old_locus_tag="BSU06180" S_feature 671929..671993 /Source="Nicolas_S_feature" /locus_tag="new_671929_671993" /HighExp="Salt, S0, aero, T-0.40H, T-1.40H, SMMPr, T-1.10H, T0.0H, Cold, GM 120" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigWXY" /TUshortPSig="0.996" /TUlongSig="NA" /TUlongPSig="NA" /label="S221" CDS 671994..673019 /gene="ydjG" /locus_tag="BSU_06190" /old_locus_tag="BSU06190" /function="16.5: Explore" /function="16.9: Replicate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type h : extrachromosomal origin" /codon_start=1 /transl_table=11 /product="putative phage replication protein; prophage region 3" /protein_id="NP_388500.1" /db_xref="EnsemblGenomes-Gn:BSU06190" /db_xref="EnsemblGenomes-Tr:CAB12438" /db_xref="GOA:O34434" /db_xref="InterPro:IPR013137" /db_xref="SubtiList:BG12798" /db_xref="UniProtKB/Swiss-Prot:O34434" /translation="MIISYKCPNCGSDMAFDSETGSLSCSSCGRQDNIESLPKENIAA RFSDDEAKEYQCKNCGAVLITEAETTATTCSFCGGAAILADRLSGHLAPAKVIPFTIS KQEAEQAFRKWCKKGLLTPRGFMSADRIKSITGMYIPFWMFDLNSEVQVRANCTRVHQ YEEGDYICTETEHFEAFRDINLDYLKIPVDASEKMKDELMDKLEPYSYEELKDFQTAY LAGYIAEKYNYTDEELFPRAKEKISSYIDSYIHSTFSGYTSVNVRDKHIHTKNVNSFY VLLPVWMVSYDYERAEHIFAMNGQTGKVVGKPPISRGKVAAWFSGIAGGTFLALKLVS LMMGGGF*" gene 671994..673019 /gene="ydjG" /locus_tag="BSU_06190" /old_locus_tag="BSU06190" CDS 673019..673783 /gene="ydjH" /locus_tag="BSU_06200" /old_locus_tag="BSU06200" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein; prophage region 3" /protein_id="NP_388501.1" /db_xref="EnsemblGenomes-Gn:BSU06200" /db_xref="EnsemblGenomes-Tr:CAB12439" /db_xref="GOA:O35004" /db_xref="InterPro:IPR007621" /db_xref="SubtiList:BG12799" /db_xref="UniProtKB/Swiss-Prot:O35004" /translation="MRGFFGKAIFVVLAVFIMMPLLGIEAVRASELQQHVYDRAHLLS KAEIGKLESLSAKLGAKRDTDFIIITTKSTNGEDIADYTGDFYDRYGKGSTAILTIDM TNREVFIAGFKKAEQYLDNSRLNSIRNTISSDLSNENYFEAFETYIQLSYKDMGIKPG VNPDNIFFTWWFQLIAAIAVGGIAVSIMLYHAGGKVTVNGSTYMDQRTSDVIDQYDTY IRTTVTRERKPSDKDSGSDGGVTKGGTSYSGSRGSF*" gene 673019..673783 /gene="ydjH" /locus_tag="BSU_06200" /old_locus_tag="BSU06200" CDS 673814..674785 /gene="ydjI" /locus_tag="BSU_06210" /old_locus_tag="BSU06210" /function="16.5: Explore" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 22720735; Product type h: extrachromosomal origin" /codon_start=1 /transl_table=11 /product="putative phage protein" /protein_id="NP_388502.1" /db_xref="EnsemblGenomes-Gn:BSU06210" /db_xref="EnsemblGenomes-Tr:CAB12440" /db_xref="InterPro:IPR033880" /db_xref="InterPro:IPR036013" /db_xref="SubtiList:BG12800" /db_xref="UniProtKB/Swiss-Prot:O34789" /translation="MSFFRNQLANVVEWEEFRDDMIFYKWNNREIKKGSRLIIRPGQD AVFLNNGRVEGVFQDDGDYDIESEIIPFLSTLKGFKFGFNSGMRAEVLFVNTKEFTVR WGTKQAINIPAAGMPGGMPIRANGTFNFKVQDYISLIDKIAGVKDQYFVEDIKTRIIS ILDQLLMKWITREGKDMFNLQANAFDIAKGIQEDLDMQLISDGMTVTGFQIMSFNYPQ EVQDMITKNASYGMVGDVNRYQQISMTDGMASGKMSGSGAASDMAGMMMGMNMANQMM NQMNQNQQAQSSGPQSTGSGSKPNFCPNCGTKTGEANFCPNCGQKLV*" gene 673814..674785 /gene="ydjI" /locus_tag="BSU_06210" /old_locus_tag="BSU06210" downshifts 674775 /Source="Nicolas_upshifts" /id="D300" /incds=0 /nref=180 /ntot=247 /MaxReadThrough="2.71622" /MaxDrop="5.81579" /score="16.72046" /energy="-11.1" /TU="U477" /idTUdmin="U477" /TUdmin="-44" /isTUend="FALSE" downshifts 674819 /Source="Nicolas_upshifts" /id="D301" /incds=0 /nref=1 /ntot=2 /MaxReadThrough="2.13813" /MaxDrop="3.25329" /score="16.72046" /energy="-11.1" /TU="NA" /idTUdmin="U477" /TUdmin=0 /isTUend="TRUE" CDS complement(674832..675857) /gene="ydjJ" /locus_tag="BSU_06220" /old_locus_tag="BSU06220" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative membrane associated potassium channel; prophage region 3" /protein_id="NP_388503.1" /db_xref="EnsemblGenomes-Gn:BSU06220" /db_xref="EnsemblGenomes-Tr:CAB12441" /db_xref="GOA:O34733" /db_xref="InterPro:IPR013099" /db_xref="SubtiList:BG12801" /db_xref="UniProtKB/Swiss-Prot:O34733" /translation="MNEGYIIAGLLLLTAGMIDFLWTTLWLESGAGPITRCLSAWLWK GCRKISGDHAKVLSMAGPLLLCLTLVIWISLFWSGWVLIYSSDPHSLMETQSKEPASW SDRIYFSGYVMFTLGNGDLAPNGGLWKLVTIIETAQGLLTITFSVTYLISVLSAVNQK RSFAQSVLSLGHDGTEIVHNAWNGKDFHDIDFLLVAASSELGKLTAQHNAFPILHFYH STQHQESSIIAVAVLDEALTIFKYGIPEQYQPNQLHIKEARSSIKNYLDTVHTAYIHP AEQAPPEPDISKLQQSGIPALSKQTFQIAVNSIKERRQLLLGIIQAGARKWPVQEQAI GNAYSPK*" gene complement(674832..675857) /gene="ydjJ" /locus_tag="BSU_06220" /old_locus_tag="BSU06220" promotor_-10 complement(675889..675908) /Source="Nicolas_upshift_promotors" /id="U478" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=251 /SigmaFactorBS="ccacctatttttctctgtaaaatcaaacattcgttcaatTGT TTCAgactcaggataaaAGGAAATAGAGAAGAAAATAaaagaaggctgacttaaggga g" /listShort="ydjJ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(675907) /Source="Nicolas_upshifts" /id="U478" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=251 /SigmaFactorBS="ccacctatttttctctgtaaaatcaaacattcgttcaatTGT TTCAgactcaggataaaAGGAAATAGAGAAGAAAATAaaagaaggctgacttaaggga g" /listShort="ydjJ" /GFF_Attribute="listLong" promotor_-35 complement(675922..675928) /Source="Nicolas_upshift_promotors" /id="U478" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=251 /SigmaFactorBS="ccacctatttttctctgtaaaatcaaacattcgttcaatTGT TTCAgactcaggataaaAGGAAATAGAGAAGAAAATAaaagaaggctgacttaaggga g" /listShort="ydjJ" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 676117..676124 /Source="Nicolas_upshift_promotors" /id="U479" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.999000999001" /psig=1 /xcortree=323 /SigmaFactorBS="tgattttccttttatagagtaaaaaattttcagaaatttaTA TTGACTgaaagcgtttttatAATTATGATAATATCAGATAtaacaaaaatgtcactat a" /listShort="S222, iolT" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 676137 /Source="Nicolas_upshifts" /id="U479" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.999000999001" /psig=1 /xcortree=323 /SigmaFactorBS="tgattttccttttatagagtaaaaaattttcagaaatttaTA TTGACTgaaagcgtttttatAATTATGATAATATCAGATAtaacaaaaatgtcactat a" /listShort="S222, iolT" /GFF_Attribute="listLong" S_feature 676139..676441 /Source="Nicolas_S_feature" /locus_tag="new_676139_676441" /HighExp="M0t90, M40t90, Lbtran, T0.30H, BI, T1.0H, M9-stat, S1, T1.30H, S0" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.28450700000000001" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S222" promotor_-10 676139..676158 /Source="Nicolas_upshift_promotors" /id="U479" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.999000999001" /psig=1 /xcortree=323 /SigmaFactorBS="tgattttccttttatagagtaaaaaattttcagaaatttaTA TTGACTgaaagcgtttttatAATTATGATAATATCAGATAtaacaaaaatgtcactat a" /listShort="S222, iolT" /GFF_Attribute="listLong" /label="promotor_-10" CDS 676442..677863 /gene="iolT" /locus_tag="BSU_06230" /old_locus_tag="BSU06230" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:11807058, 15849754, 16850406, 22720735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11807058, 15849754, 16850406, 22720735; Product type t: transporter" /codon_start=1 /transl_table=11 /product="myo-inositol transporter" /protein_id="NP_388504.1" /db_xref="EnsemblGenomes-Gn:BSU06230" /db_xref="EnsemblGenomes-Tr:CAB12442" /db_xref="GOA:O34718" /db_xref="InterPro:IPR003663" /db_xref="InterPro:IPR005828" /db_xref="InterPro:IPR005829" /db_xref="InterPro:IPR020846" /db_xref="InterPro:IPR036259" /db_xref="SubtiList:BG12802" /db_xref="UniProtKB/Swiss-Prot:O34718" /translation="MNKQGNQMSFLRTIILVSTFGGLLFGYDTGVLNGALPYMGEPDQ LNLNAFTEGLVTSSLLFGAALGAVFGGRMSDFNGRRKNILFLAVIFFISTIGCTFAPN VTVMIISRFVLGIAVGGASVTVPAYLAEMSPVESRGRMVTQNELMIVSGQLLAFVFNA ILGTTMGDNSHVWRFMLVIASLPALFLFFGMIRMPESPRWLVSKGRKEDALRVLKKIR DEKRAAAELQEIEFAFKKEDQLEKATFKDLSVPWVRRIVFIGLGIAIVQQITGVNSIM YYGTEILRNSGFQTEAALIGNIANGVISVLATFVGIWLLGRVGRRPMLMTGLIGTTTA LLLIGIFSLVLEGSPALPYVVLSLTVTFLAFQQGAISPVTWLMLSEIFPLRLRGLGMG VTVFCLWMVNFAVSFTFPILLAAIGLSTTFFIFVGLGICSVLFVKRFLPETKGLSLEQ LEENFRAYDHSGAKKDSGAEVIG*" gene 676442..677863 /gene="iolT" /locus_tag="BSU_06230" /old_locus_tag="BSU06230" downshifts 677855 /Source="Nicolas_upshifts" /id="D302" /incds=0 /nref=11 /ntot=24 /MaxReadThrough="2.82455" /MaxDrop="8.02371" /score="11.3880907" /energy="-11.2" /TU="NA" /idTUdmin="U479" /TUdmin=0 /isTUend="TRUE" downshifts complement(677911) /Source="Nicolas_upshifts" /id="D303" /incds=0 /nref=242 /ntot=272 /MaxReadThrough="1.00274" /MaxDrop="9.32541" /score="13.6781112" /energy="-11.2" /TU="NA" /idTUdmin="U482" /TUdmin="-2" /isTUend="TRUE" CDS complement(677911..678951) /gene="bdhA" /locus_tag="BSU_06240" /old_locus_tag="BSU06240" /EC_number="1.1.1.4" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:12469342, 18820069, 24525333, 26428232, 22720735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12469342, 18820069, 24525333, 26428232, 22720735; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="acetoin reductase/2,3-butanediol dehydrogenase" /protein_id="NP_388505.1" /db_xref="EnsemblGenomes-Gn:BSU06240" /db_xref="EnsemblGenomes-Tr:CAB12443" /db_xref="GOA:O34788" /db_xref="InterPro:IPR002328" /db_xref="InterPro:IPR011032" /db_xref="InterPro:IPR013149" /db_xref="InterPro:IPR013154" /db_xref="InterPro:IPR020843" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG12803" /db_xref="UniProtKB/Swiss-Prot:O34788" /translation="MKAARWHNQKDIRIEHIEEPKTEPGKVKIKVKWCGICGSDLHEY LGGPIFIPVDKPHPLTNETAPVTMGHEFSGEVVEVGEGVENYKVGDRVVVEPIFATHG HQGAYNLDEQMGFLGLAGGGGGFSEYVSVDEELLFKLPDELSYEQGALVEPSAVALYA VRSSKLKAGDKAAVFGCGPIGLLVIEALKAAGATDIYAVELSPERQQKAEELGAIIVD PSKTDDVVAEIAERTGGGVDVAFEVTGVPVVLRQAIQSTTIAGETVIVSIWEKGAEIH PNDIVIKERTVKGIIGYRDIFPAVLSLMKEGYFSADKLVTKKIVLDDLIEEGFGALIK EKSQVKILVRPN*" gene complement(677911..678951) /gene="bdhA" /locus_tag="BSU_06240" /old_locus_tag="BSU06240" promotor_-35 678491..678500 /Source="Nicolas_upshift_promotors" /id="U480" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=1246 /SigmaFactorBS="agtttgcttgagcggacagcgtatagagcaactgcaGAAGGT TCAAcgagcgcgccttgTTCATATGATAATTCATCAGgaagtttgaacaaaagctctt c" /listShort="S223" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 678514..678533 /Source="Nicolas_upshift_promotors" /id="U480" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=1246 /SigmaFactorBS="agtttgcttgagcggacagcgtatagagcaactgcaGAAGGT TCAAcgagcgcgccttgTTCATATGATAATTCATCAGgaagtttgaacaaaagctctt c" /listShort="S223" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 678515..679050 /Source="Nicolas_S_feature" /locus_tag="new_678515_679050" /HighExp="C30, Gly, S6, C90, S8, BT, S7, Sw, Fru, Lbstat" /AntisenseName="bdhA" /AntisenseCor="-0.174163895138467" /AntisenseRegPval="-2.4" /CDS_PredictionProba="NA" /TUshortSig="SigK" /TUshortPSig="0.998" /TUlongSig="NA" /TUlongPSig="NA" /label="S223" upshifts 678515 /Source="Nicolas_upshifts" /id="U480" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=1246 /SigmaFactorBS="agtttgcttgagcggacagcgtatagagcaactgcaGAAGGT TCAAcgagcgcgccttgTTCATATGATAATTCATCAGgaagtttgaacaaaagctctt c" /listShort="S223" /GFF_Attribute="listLong" S_feature complement(678952..679246) /Source="Nicolas_S_feature" /locus_tag="new_678952_679246_c" /HighExp="Lbtran, BI, T1.0H, M40t90, LBGstat, LoTm, T0.30H, LPhT, Lbstat, ferm" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.99" /TUlongSig="NA" /TUlongPSig="NA" /label="S224" misc_feature 679051..679070 /Source="Nicolas_upshift_promotors" /id="U481" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.866133866133866" /psig="0.994005994005994" /xcortree=1752 /SigmaFactorBS="accggtcaatatgaactgttcacaaaatcgccatttttaaaa ccaaaaaagaaatgaaaTTTTTATATAATATAATCTAcgtttttttgaaaaaaagaaa c" /listShort="S225" /listLong="ydjM, ydjN" /label="promotor_single_box" /note="Geneious type: promotor_single_box" S_feature 679052..679349 /Source="Nicolas_S_feature" /locus_tag="new_679052_679349" /HighExp="G180, Paraq, Oxctl, H2O2, G135, G150, MG 5, C30, UNK1, MG 15" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.994" /TUlongSig="NA" /TUlongPSig="NA" /label="S225" upshifts 679052 /Source="Nicolas_upshifts" /id="U481" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.866133866133866" /psig="0.994005994005994" /xcortree=1752 /SigmaFactorBS="accggtcaatatgaactgttcacaaaatcgccatttttaaaa ccaaaaaagaaatgaaaTTTTTATATAATATAATCTAcgtttttttgaaaaaaagaaa c" /listShort="S225" /listLong="ydjM, ydjN" misc_feature complement(679241..679255) /Source="Nicolas_upshift_promotors" /id="U482" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.598401598401598" /psig="0.99000999000999" /xcortree=3201 /SigmaFactorBS="tacaaagtcaaaaaagttacctctgctaaaataaaccatgga agattatccTATTATAATAGCAGTattagagttataattattgatagagtagttgtcg c" /listShort="S224, bdhA" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(679246) /Source="Nicolas_upshifts" /id="U482" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.598401598401598" /psig="0.99000999000999" /xcortree=3201 /SigmaFactorBS="tacaaagtcaaaaaagttacctctgctaaaataaaccatgga agattatccTATTATAATAGCAGTattagagttataattattgatagagtagttgtcg c" /listShort="S224, bdhA" /GFF_Attribute="listLong" promotor_-35 679329 /Source="Nicolas_upshift_promotors" /id="U483" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.462537462537463" /psig="0.998001998001998" /xcortree=3034 /SigmaFactorBS="cttttttgactttgtaacattactgtaaggatattgaaAtaa aaaatagctggttgaTCGTGTATAATCTTCCTAGAtgttaacaaacagggggacgaaa t" /listShort="ydjM, ydjN" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 679348..679367 /Source="Nicolas_upshift_promotors" /id="U483" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.462537462537463" /psig="0.998001998001998" /xcortree=3034 /SigmaFactorBS="cttttttgactttgtaacattactgtaaggatattgaaAtaa aaaatagctggttgaTCGTGTATAATCTTCCTAGAtgttaacaaacagggggacgaaa t" /listShort="ydjM, ydjN" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 679351 /Source="Nicolas_upshifts" /id="U483" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.462537462537463" /psig="0.998001998001998" /xcortree=3034 /SigmaFactorBS="cttttttgactttgtaacattactgtaaggatattgaaAtaa aaaatagctggttgaTCGTGTATAATCTTCCTAGAtgttaacaaacagggggacgaaa t" /listShort="ydjM, ydjN" /GFF_Attribute="listLong" CDS 679390..679761 /gene="walM" /locus_tag="BSU_06250" /old_locus_tag="BSU06250" /experiment="publication(s) with functional evidences, PMID:17581128, 20487291" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 17581128, 20487291; Product type f: factor" /codon_start=1 /transl_table=11 /product="protein involved in cell wall metabolism" /protein_id="NP_388506.1" /db_xref="EnsemblGenomes-Gn:BSU06250" /db_xref="EnsemblGenomes-Tr:CAB12444" /db_xref="InterPro:IPR009009" /db_xref="InterPro:IPR036908" /db_xref="SubtiList:BG11036" /db_xref="UniProtKB/Swiss-Prot:P40775" /translation="MLKKVILAAFILVGSTLGAFSFSSDASAKHVNGNITWYNGVGKK GSSGKKLGHWDCATKIGFDVPRNGTKIRAYAKAKPKKVITVYKNDVGRMPNAVLDVSP KAFKALGYPLSKGKVAGHYSY*" gene 679390..679761 /gene="walM" /locus_tag="BSU_06250" /old_locus_tag="BSU06250" downshifts 679747 /Source="Nicolas_upshifts" /id="D304" /incds=0 /nref=5 /ntot=52 /MaxReadThrough="5.74148" /MaxDrop="2.8439" /score="-1.55787542" /energy="-7.4" /TU="U483" /idTUdmin="U481" /TUdmin=418 /isTUend="FALSE" CDS 679827..680873 /gene="ydjN" /locus_tag="BSU_06260" /old_locus_tag="BSU06260" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative membrane protein" /protein_id="NP_388507.1" /db_xref="EnsemblGenomes-Gn:BSU06260" /db_xref="EnsemblGenomes-Tr:CAB12445" /db_xref="InterPro:IPR011659" /db_xref="InterPro:IPR015943" /db_xref="SubtiList:BG12804" /db_xref="UniProtKB/Swiss-Prot:O34353" /translation="MKKRIILLLAVIIAAAAAGVAFYVAKDKGHEKAADVSVNTESGD ELLVSITDTDLLTKYYENDKVIHEEKLTSYPAFALDQKQQVLYYTGNNEQNEMRLFKL DLKSHKKTMLYKGAESADSLFLSKDRSTIYFRLGKADESNFRIAAFDLKTKKYKNLYP AANDQDDTVSSFFYNQKNDSFALLHYSVEEDYKKTDEANEKGIDPEPTTIHFAEGRQN KFNELKSLNQFISDIAVSDDDKRILFTSYTQKGTEQTASIQMLNADTKKYESIISNQK SFKLLIDAQPQFSKDGKNIYFLAEAKGAKKLKDETGREAKVRTIYSYSLENKTFKKVW ENPNGIINSFFVIN*" gene 679827..680873 /gene="ydjN" /locus_tag="BSU_06260" /old_locus_tag="BSU06260" downshifts 680847 /Source="Nicolas_upshifts" /id="D305" /incds=0 /nref=41 /ntot=177 /MaxReadThrough="1.73572" /MaxDrop="4.49184" /score="21.8200083" /energy="-13.9" /TU="NA" /idTUdmin="U483" /TUdmin=0 /isTUend="TRUE" CDS complement(680907..681065) /gene="ydzJ" /locus_tag="BSU_06269" /old_locus_tag="BSU06269" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_003097689.1" /db_xref="EnsemblGenomes-Gn:BSU06269" /db_xref="EnsemblGenomes-Tr:CAX52576" /db_xref="GOA:O24817" /db_xref="UniProtKB/Swiss-Prot:O24817" /translation="MISNQQQKDLKKRAAFKKLNVAMNSYVELLFLSVPLIHIFKWLG SLALHLIH*" gene complement(680907..681065) /gene="ydzJ" /locus_tag="BSU_06269" /old_locus_tag="BSU06269" downshifts complement(680923) /Source="Nicolas_upshifts" /id="D306" /incds=0 /nref=23 /ntot=155 /MaxReadThrough="0.7906" /MaxDrop="3.61386" /score="9.10659473" /energy="-10.1" /TU="NA" /idTUdmin="U487" /TUdmin=0 /isTUend="TRUE" S_feature complement(681122..681254) /Source="Nicolas_S_feature" /locus_tag="new_681122_681254_c" /HighExp="LoTm, S8, S5, S6, S4, B36, S7, Cold, B60, Salt" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigEF, SigWXY" /TUshortPSig="0.994, 1, 1" /TUlongSig="SigK" /TUlongPSig="0.994" /label="S226" downshifts complement(681165) /Source="Nicolas_upshifts" /id="D307" /incds=0 /nref=57 /ntot=272 /MaxReadThrough="3.03092" /MaxDrop="6.46708" /score="5.41743429" /energy="-8.4" /TU="U484,U486,U487" /idTUdmin="U484" /TUdmin="-22" /isTUend="TRUE" CDS complement(681255..681464) /gene="ydjO" /locus_tag="BSU_06270" /old_locus_tag="BSU06270" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 28197687" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_388508.1" /db_xref="EnsemblGenomes-Gn:BSU06270" /db_xref="EnsemblGenomes-Tr:CAB12446" /db_xref="InterPro:IPR025916" /db_xref="SubtiList:BG12805" /db_xref="UniProtKB/Swiss-Prot:O34759" /translation="MSYYNKRNQEPLPKEDVSTWECTKEDCNGWTRKNFASSDTPLCP LCGSKMVDGIRSLVNLQNNSQTKTS*" gene complement(681255..681464) /gene="ydjO" /locus_tag="BSU_06270" /old_locus_tag="BSU06270" promotor_-10 complement(681497..681516) /Source="Nicolas_upshift_promotors" /id="U484" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.66033966033966" /psig="0.994005994005994" /xcortree=586 /SigmaFactorBS="tggggttattggaaagtcataaagaaaaaggaattAggagat tagggaaaagTATGAGACAATAGGAAATGTgcagtaaaatacatgagggaagaagtga c" /listShort="ydjO, S226" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(681508) /Source="Nicolas_upshifts" /id="U484" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.66033966033966" /psig="0.994005994005994" /xcortree=586 /SigmaFactorBS="tggggttattggaaagtcataaagaaaaaggaattAggagat tagggaaaagTATGAGACAATAGGAAATGTgcagtaaaatacatgagggaagaagtga c" /listShort="ydjO, S226" /GFF_Attribute="listLong" promotor_-35 complement(681533) /Source="Nicolas_upshift_promotors" /id="U484" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.66033966033966" /psig="0.994005994005994" /xcortree=586 /SigmaFactorBS="tggggttattggaaagtcataaagaaaaaggaattAggagat tagggaaaagTATGAGACAATAGGAAATGTgcagtaaaatacatgagggaagaagtga c" /listShort="ydjO, S226" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(681547..682362) /gene="ydjP" /locus_tag="BSU_06280" /old_locus_tag="BSU06280" /function="16.11: Scavenge (Catabolism)" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 9987136; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative aminoacrylate hydrolase" /protein_id="NP_388509.1" /db_xref="EnsemblGenomes-Gn:BSU06280" /db_xref="EnsemblGenomes-Tr:CAB12447" /db_xref="GOA:O34592" /db_xref="InterPro:IPR000073" /db_xref="InterPro:IPR029058" /db_xref="SubtiList:BG12806" /db_xref="UniProtKB/Swiss-Prot:O34592" /translation="MPYIILEDQTRLYYETHGSGTPILFIHGVLMSGQFFHKQFSVLS ANYQCIRLDLRGHGESDKVLHGHTISQYARDIREFLNAMELDHVVLAGWSMGAFVVWD YLNQFGNDNIQAAVIIDQSASDYQWEGWEHGPFDFDGLKTAMHAIQTDPLPFYESFIQ NMFAEPPAETETEWMLAEILKQPAAISSTILFNQTAADYRGTLQNINVPALLCFGEDK KFFSTAAGEHLRSNIPNATLVTFPKSSHCPFLEEPDAFNSTLLSFLDGVIGKS*" gene complement(681547..682362) /gene="ydjP" /locus_tag="BSU_06280" /old_locus_tag="BSU06280" promotor_-35 682189..682198 /Source="Nicolas_upshift_promotors" /id="U485" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.994005994005994" /psig="0.994005994005994" /xcortree=1434 /SigmaFactorBS="tgggaaatggtgtggccgtgaagcactttgtcagattcGCCG TGTCCTctaagatcaagaCGAATACATTGATAATTGGCagaaagcaccgaaaattgtt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 682211..682230 /Source="Nicolas_upshift_promotors" /id="U485" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.994005994005994" /psig="0.994005994005994" /xcortree=1434 /SigmaFactorBS="tgggaaatggtgtggccgtgaagcactttgtcagattcGCCG TGTCCTctaagatcaagaCGAATACATTGATAATTGGCagaaagcaccgaaaattgtt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 682211 /Source="Nicolas_upshifts" /id="U485" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.994005994005994" /psig="0.994005994005994" /xcortree=1434 /SigmaFactorBS="tgggaaatggtgtggccgtgaagcactttgtcagattcGCCG TGTCCTctaagatcaagaCGAATACATTGATAATTGGCagaaagcaccgaaaattgtt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" CDS complement(682375..683364) /gene="yeaA" /locus_tag="BSU_06290" /old_locus_tag="BSU06290" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_388510.1" /db_xref="EnsemblGenomes-Gn:BSU06290" /db_xref="EnsemblGenomes-Tr:CAB12448" /db_xref="InterPro:IPR025062" /db_xref="SubtiList:BG12210" /db_xref="UniProtKB/Swiss-Prot:O34803" /translation="MLTHDLHEKTKHYISIYAELKTKLKWKVSHDQILMLISSAYIVN KREFDFQRFYDLSSYIKSNIGSFSTLNSHHRFTVASILDIHFQHEAKQTFQTFIDVYN EMVKLGYKRDMFTYLSALILLTGKSETTNQKEQMNMGLAVYQQMKKNHYFLTSTQNVP LAVLLGENGKGLQALQKAETCYQLLAANGFKKGQYLHQVSHILALQSEKEPEMLVSAC KQIYQSITESVKKTKDYHYPDLALLTFLEEPDIKTVLCITDELNQEKAFKWQKEMNFK IAVSLYLSEHMEKNLLMESGLYTAIETVIQAQQAAATAAIISSTAASHTHDGN*" gene complement(682375..683364) /gene="yeaA" /locus_tag="BSU_06290" /old_locus_tag="BSU06290" promotor_-10 complement(683229..683247) /Source="Nicolas_upshift_promotors" /id="U486" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1147 /SigmaFactorBS="aattaaaatggaaagtttcacacgatcagATATTAatgctca tttcttctGCATATATTGTGAATAAAAgagagtttgattttcagcgcttttatgattt g" /listShort="ydjP, ydjO, S226" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(683237) /Source="Nicolas_upshifts" /id="U486" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1147 /SigmaFactorBS="aattaaaatggaaagtttcacacgatcagATATTAatgctca tttcttctGCATATATTGTGAATAAAAgagagtttgattttcagcgcttttatgattt g" /listShort="ydjP, ydjO, S226" /GFF_Attribute="listLong" promotor_-35 complement(683263..683268) /Source="Nicolas_upshift_promotors" /id="U486" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1147 /SigmaFactorBS="aattaaaatggaaagtttcacacgatcagATATTAatgctca tttcttctGCATATATTGTGAATAAAAgagagtttgattttcagcgcttttatgattt g" /listShort="ydjP, ydjO, S226" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(683386..683401) /Source="Nicolas_upshift_promotors" /id="U487" /multdbtbs="SigW" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1666 /SigmaFactorBS="aaataacccgacaaacttgcctctagcaggcaagttttttct ttaTGAAACCTTTggccctatttaTCGTATTACGTAAAAAcaacaaaaggagctgctt t" /listShort="yeaA, ydjP, ydjO, S226, ydzJ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(683407) /Source="Nicolas_upshifts" /id="U487" /multdbtbs="SigW" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1666 /SigmaFactorBS="aaataacccgacaaacttgcctctagcaggcaagttttttct ttaTGAAACCTTTggccctatttaTCGTATTACGTAAAAAcaacaaaaggagctgctt t" /listShort="yeaA, ydjP, ydjO, S226, ydzJ" /GFF_Attribute="listLong" promotor_-35 complement(683413..683422) /Source="Nicolas_upshift_promotors" /id="U487" /multdbtbs="SigW" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1666 /SigmaFactorBS="aaataacccgacaaacttgcctctagcaggcaagttttttct ttaTGAAACCTTTggccctatttaTCGTATTACGTAAAAAcaacaaaaggagctgctt t" /listShort="yeaA, ydjP, ydjO, S226, ydzJ" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(683462..685003) /gene="cotA" /locus_tag="BSU_06300" /old_locus_tag="BSU06300" /EC_number="1.3.3.5" /function="16.6: Maintain" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:11514528, 12637519, 16391148, 17242517, 18031270, 19933362, 22112278, 25259857, 27050268" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11514528, 12637519, 16391148, 17242517, 18031270, 19933362, 22112278, 25259857, 27050268; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="outer spore coat copper-dependent promiscuous laccase" /protein_id="NP_388511.1" /db_xref="EnsemblGenomes-Gn:BSU06300" /db_xref="EnsemblGenomes-Tr:CAB12449" /db_xref="GOA:P07788" /db_xref="InterPro:IPR001117" /db_xref="InterPro:IPR008972" /db_xref="InterPro:IPR011706" /db_xref="InterPro:IPR011707" /db_xref="PDB:1GSK" /db_xref="PDB:1OF0" /db_xref="PDB:1W6L" /db_xref="PDB:1W6W" /db_xref="PDB:1W8E" /db_xref="PDB:2BHF" /db_xref="PDB:2WSD" /db_xref="PDB:2X87" /db_xref="PDB:2X88" /db_xref="PDB:3ZDW" /db_xref="PDB:4A66" /db_xref="PDB:4A67" /db_xref="PDB:4A68" /db_xref="PDB:4AKO" /db_xref="PDB:4AKP" /db_xref="PDB:4AKQ" /db_xref="PDB:4Q89" /db_xref="PDB:4Q8B" /db_xref="PDB:4YVN" /db_xref="PDB:4YVU" /db_xref="SubtiList:BG10490" /db_xref="UniProtKB/Swiss-Prot:P07788" /translation="MTLEKFVDALPIPDTLKPVQQSKEKTYYEVTMEECTHQLHRDLP PTRLWGYNGLFPGPTIEVKRNENVYVKWMNNLPSTHFLPIDHTIHHSDSQHEEPEVKT VVHLHGGVTPDDSDGYPEAWFSKDFEQTGPYFKREVYHYPNQQRGAILWYHDHAMALT RLNVYAGLVGAYIIHDPKEKRLKLPSDEYDVPLLITDRTINEDGSLFYPSAPENPSPS LPNPSIVPAFCGETILVNGKVWPYLEVEPRKYRFRVINASNTRTYNLSLDNGGDFIQI GSDGGLLPRSVKLNSFSLAPAERYDIIIDFTAYEGESIILANSAGCGGDVNPETDANI MQFRVTKPLAQKDESRKPKYLASYPSVQHERIQNIRTLKLAGTQDEYGRPVLLLNNKR WHDPVTETPKVGTTEIWSIINPTRGTHPIHLHLVSFRVLDRRPFDIARYQESGELSYT GPAVPPPPSEKGWKDTIQAHAGEVLRIAATFGPYSGRYVWHCHILEHEDYDMMRPMDI TDPHK*" gene complement(683462..685003) /gene="cotA" /locus_tag="BSU_06300" /old_locus_tag="BSU06300" downshifts complement(683475) /Source="Nicolas_upshifts" /id="D308" /incds=0 /nref=46 /ntot=93 /MaxReadThrough="2.97674" /MaxDrop="5.60726" /score="22.3755425" /energy="-9.1" /TU="U488" /idTUdmin="U488" /TUdmin="-66" /isTUend="FALSE" promotor_-10 complement(685034..685053) /Source="Nicolas_upshift_promotors" /id="U488" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp="0.994005994005994" /psig="0.994005994005994" /xcortree=1297 /SigmaFactorBS="tcttcttcgggcgggctgcagcacgaagatttTTTGTAACCA tcacgtccttattGTCATTAACTATAGTACCAAtttggaaaatttagataaggacaga t" /listShort="cotA" /listLong="yeaA, ydjP, ydjO, S226" /label="promotor_-10" upshifts complement(685048) /Source="Nicolas_upshifts" /id="U488" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp="0.994005994005994" /psig="0.994005994005994" /xcortree=1297 /SigmaFactorBS="tcttcttcgggcgggctgcagcacgaagatttTTTGTAACCA tcacgtccttattGTCATTAACTATAGTACCAAtttggaaaatttagataaggacaga t" /listShort="cotA" /listLong="yeaA, ydjP, ydjO, S226" promotor_-35 complement(685067..685076) /Source="Nicolas_upshift_promotors" /id="U488" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp="0.994005994005994" /psig="0.994005994005994" /xcortree=1297 /SigmaFactorBS="tcttcttcgggcgggctgcagcacgaagatttTTTGTAACCA tcacgtccttattGTCATTAACTATAGTACCAAtttggaaaatttagataaggacaga t" /listShort="cotA" /listLong="yeaA, ydjP, ydjO, S226" /label="promotor_-35" CDS complement(685155..686564) /gene="gabP" /locus_tag="BSU_06310" /old_locus_tag="BSU06310" /function="16.1: Circulate" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:15849754, 16547045, 16850406, 8951816, 9677314, 24142252" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15849754, 16547045, 16850406, 8951816, 9677314, 24142252; Product type t : transporter" /codon_start=1 /transl_table=11 /product="gamma-aminobutyrate (GABA) permease; proline permease" /protein_id="NP_388512.2" /db_xref="EnsemblGenomes-Gn:BSU06310" /db_xref="EnsemblGenomes-Tr:CAB12450" /db_xref="GOA:P46349" /db_xref="InterPro:IPR002293" /db_xref="InterPro:IPR004840" /db_xref="InterPro:IPR004841" /db_xref="InterPro:IPR011265" /db_xref="SubtiList:BG11328" /db_xref="UniProtKB/Swiss-Prot:P46349" /translation="MNQSQSGLKKELKTRHMTMISIAGVIGAGLFVGSGSVIHSTGPG AVVSYALAGLLVIFIMRMLGEMSAVNPTSGSFSQYAHDAIGPWAGFTIGWLYWFFWVI VIAIEAIAGAGIIQYWFHDIPLWLTSLILTIVLTLTNVYSVKSFGEFEYWFSLIKVVT IIAFLIVGFAFIFGFAPGSEPVGFSNLTGKGGFFPEGISSVLLGIVVVIFSFMGTEIV AIAAGETSNPIESVTKATRSVVWRIIVFYVGSIAIVVALLPWNSANILESPFVAVLEH IGVPAAAQIMNFIVLTAVLSCLNSGLYTTSRMLYSLAERNEAPRRFMKLSKKGVPVQA IVAGTFFSYIAVVMNYFSPDTVFLFLVNSSGAIALLVYLVIAVSQLKMRKKLEKTNPE ALKIKMWLFPFLTYLTIIAICGILVSMAFIDSMRDELLLTGVITGIVLISYLVFRKRK VSEKAAANPVTQQQPDILP*" gene complement(685155..686564) /gene="gabP" /locus_tag="BSU_06310" /old_locus_tag="BSU06310" downshifts complement(685169) /Source="Nicolas_upshifts" /id="D309" /incds=0 /nref=124 /ntot=216 /MaxReadThrough="3.22899" /MaxDrop="5.0359" /score="18.985683" /energy="-13.5" /TU="U489" /idTUdmin="U489" /TUdmin="-110" /isTUend="FALSE" CDS complement(686602..686889) /gene="ydzX" /locus_tag="BSU_06319" /old_locus_tag="BSU06319" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_003097690.1" /db_xref="EnsemblGenomes-Gn:BSU06319" /db_xref="EnsemblGenomes-Tr:CAX52577" /db_xref="UniProtKB/Swiss-Prot:C0H3X2" /translation="MIHPPQKNSDEGTLFLSSNLFAPPKIPSNPRTPVLLAFYRIVNI TQNHTANKKRNIFSTHSLKAQTKHYKFEISWYIFLHEFSTNCIFMIEFQLS*" gene complement(686602..686889) /gene="ydzX" /locus_tag="BSU_06319" /old_locus_tag="BSU06319" misc_feature complement(686605..686624) /Source="Nicolas_upshift_promotors" /id="U489" /multdbtbs="SigA,SigA" /comp="M14" /sig="SigA" /pcomp="0.447552447552448" /psig="0.996003996003996" /xcortree=2898 /SigmaFactorBS="tttgaaataagctggtatattttcttacacgaattttcgaca aactgtatatttaTGATAGAGTTTCAATTATCAtaatattcagtaatgattgcatttt a" /listShort="gabP" /listLong="cotA" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(686619) /Source="Nicolas_upshifts" /id="U489" /multdbtbs="SigA,SigA" /comp="M14" /sig="SigA" /pcomp="0.447552447552448" /psig="0.996003996003996" /xcortree=2898 /SigmaFactorBS="tttgaaataagctggtatattttcttacacgaattttcgaca aactgtatatttaTGATAGAGTTTCAATTATCAtaatattcagtaatgattgcatttt a" /listShort="gabP" /listLong="cotA" promotor_-35 686895..686902 /Source="Nicolas_upshift_promotors" /id="U490" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.748251748251748" /psig="0.999000999001" /xcortree=1749 /SigmaFactorBS="cgtcactatttttctgtggcgggtgaatcatgtttcTGTAGA CCcactgcggatcagctTTGTAAGATAATAATAGGAAaatgtgagcgagaggaggttt t" /listShort="yeaB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 686918..686937 /Source="Nicolas_upshift_promotors" /id="U490" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.748251748251748" /psig="0.999000999001" /xcortree=1749 /SigmaFactorBS="cgtcactatttttctgtggcgggtgaatcatgtttcTGTAGA CCcactgcggatcagctTTGTAAGATAATAATAGGAAaatgtgagcgagaggaggttt t" /listShort="yeaB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 686919 /Source="Nicolas_upshifts" /id="U490" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.748251748251748" /psig="0.999000999001" /xcortree=1749 /SigmaFactorBS="cgtcactatttttctgtggcgggtgaatcatgtttcTGTAGA CCcactgcggatcagctTTGTAAGATAATAATAGGAAaatgtgagcgagaggaggttt t" /listShort="yeaB" /GFF_Attribute="listLong" CDS 686962..687834 /gene="mneS" /locus_tag="BSU_06320" /old_locus_tag="BSU06320" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:27748968" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 27748968; Product type t: transporter" /codon_start=1 /transl_table=11 /product="secondary Mn(II) exporter, promiscuous" /protein_id="NP_388513.1" /db_xref="EnsemblGenomes-Gn:BSU06320" /db_xref="EnsemblGenomes-Tr:CAB12451" /db_xref="GOA:P46348" /db_xref="InterPro:IPR002524" /db_xref="InterPro:IPR027469" /db_xref="InterPro:IPR027470" /db_xref="InterPro:IPR036837" /db_xref="SubtiList:BG11329" /db_xref="UniProtKB/Swiss-Prot:P46348" /translation="MERYDELKKGESGALVSIAAYLVLSAIKLIIGYLFHSEALTADG LNNTTDIIASVAVLIGLRISQKPPDEDHPYGHFRAETIASLIASFIMMVVGLQVLFSA GESIFSAKQETPDMIAAWTAAGGAVLMLIVYRYNKRLAKKVKSQALLAAAADNKSDAF VSIGTFIGIVAAQFHLAWIDTVTAFVIGLLICKTAWDIFKESSHSLTDGFDIKDISAY KQTIEKISGVSRLKDIKARYLGSTVHVDVVVEVSADLNITESHDIANEIERRMKEEHA IDYSHVHMEPLEQK*" gene 686962..687834 /gene="mneS" /locus_tag="BSU_06320" /old_locus_tag="BSU06320" downshifts 687799 /Source="Nicolas_upshifts" /id="D310" /incds=0 /nref=2 /ntot=88 /MaxReadThrough="1.72291" /MaxDrop="2.86431" /score="24.8167732" /energy="-10.2" /TU="U490" /idTUdmin="U490" /TUdmin="-22" /isTUend="TRUE" downshifts complement(688074) /Source="Nicolas_upshifts" /id="D311" /incds=0 /nref=1 /ntot=3 /MaxReadThrough="0.65827" /MaxDrop="3.33542" /score="-0.424989042" /energy="-12.9" /TU="NA" /idTUdmin="U489" /TUdmin="-3015" /isTUend="FALSE" misc_feature 688128..688147 /Source="Nicolas_upshift_promotors" /id="U491" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.932067932067932" /psig=1 /xcortree=2248 /SigmaFactorBS="ctttattggtaacaatttgctagaatcgtttttttatacaga ttgcttttTGTGGTAAAGTTAGGTTACAttatgatgaattttgtagatgactaggagg a" /listShort="yeaC, yeaD, yebA" /listLong="S227, guaA" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 688138 /Source="Nicolas_upshifts" /id="U491" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.932067932067932" /psig=1 /xcortree=2248 /SigmaFactorBS="ctttattggtaacaatttgctagaatcgtttttttatacaga ttgcttttTGTGGTAAAGTTAGGTTACAttatgatgaattttgtagatgactaggagg a" /listShort="yeaC, yeaD, yebA" /listLong="S227, guaA" CDS 688184..689146 /gene="yeaC" /locus_tag="BSU_06330" /old_locus_tag="BSU06330" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 21907250, 26933057; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative MoxR-like ATPase" /protein_id="NP_388514.2" /db_xref="EnsemblGenomes-Gn:BSU06330" /db_xref="EnsemblGenomes-Tr:CAB12452" /db_xref="GOA:P94474" /db_xref="InterPro:IPR011703" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG12211" /db_xref="UniProtKB/Swiss-Prot:P94474" /translation="MAYQEDLHPLLGKAVEHINRVMVGKRDIAILSLAALLAKGHVLL EDVPGVGKTMMVRALAKSIGADFKRIQFTPDLLPSDVTGVSIYNAKTMEFEYRPGPIM GNIVLADEINRTSPKTQSALLEAMEEGSVTVDGHTMQLADPFFVMATQNPVEYEGTYP LPEAQLDRFLFKLRMGYPSFNEELDVLSLQEKSHPIETLEPVIAKEDFIFLQREVQNV RADDSIKEYIVEIVQKTRQHPSVQLGVSPRGSIALMKAAQAYALLHHRDYVIPDDIQY LAPFTLPHRMMLHPEAKFEGIQAEAIVREIMSAVKVPVQRSAVR*" gene 688184..689146 /gene="yeaC" /locus_tag="BSU_06330" /old_locus_tag="BSU06330" CDS 689146..690342 /gene="yeaD" /locus_tag="BSU_06340" /old_locus_tag="BSU06340" /function="18: Unknown function" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_388515.2" /db_xref="EnsemblGenomes-Gn:BSU06340" /db_xref="EnsemblGenomes-Tr:CAB12453" /db_xref="InterPro:IPR002881" /db_xref="InterPro:IPR036465" /db_xref="SubtiList:BG12212" /db_xref="UniProtKB/Swiss-Prot:P94475" /translation="MNKKWQWLVYGWKLIILTLLTAAVFSYAMFQGGFVSWFLFYAFL PFVLYAGLLALYPLRSFQASRQMDKTQLHAGDRLGVTVTLRRKLPFPLMYMVIEDCLP EGIESLNRDGAAAKRLVFPWFKRSMTMSYELARVPRGEHHFHSVRVRTGDVLGLIEKT AFFELDDTLFVYPFYQRFSYQVNERHQEDGVSGSSPIHQHHSSVAASVRNYQPGDRFA ALDWKTSARRSQLMTKEFEPSRSKNLFLLMDRFSSDAFEEVVSVTASILHSVLKNGAG AGLASIGKEKNIFPIQEGDQHFKHMLRHLAIAHCDAADPISRYAREELGKPSVRQADQ VVVTGQLTEDMLHLAEIGGGRVTVILAKEKDAELSQAENVMIERMMKRQIRVRIMRGG RVSRVV*" gene 689146..690342 /gene="yeaD" /locus_tag="BSU_06340" /old_locus_tag="BSU06340" CDS 690364..692577 /gene="yebA" /locus_tag="BSU_06350" /old_locus_tag="BSU06350" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_388516.2" /db_xref="EnsemblGenomes-Gn:BSU06350" /db_xref="EnsemblGenomes-Tr:CAB12454" /db_xref="GOA:P94476" /db_xref="InterPro:IPR002931" /db_xref="InterPro:IPR025403" /db_xref="InterPro:IPR036985" /db_xref="SubtiList:BG12213" /db_xref="UniProtKB/Swiss-Prot:P94476" /translation="MPHDDHKGSRLSLLLFYFLAFLLLWEWLRPLDSFTETKHTGFFS VFIGLTFLLTFFRMRWFVTVPFCVIFTLISIHILFYQGSIFDLSWVSSFLQDVYLNIT LIQSGQWNDMIPSFRTLLFFVLLWLLVYLLHYWVIYQRRILFFFLMTVAYITILDTFT PYDATFAVIRIVLIGFFMLGLLYLERIKLMERITLPKTSVLKWFLPLSVLVLAATGFG LAAPKSEPAWPDPVPFLKKITHQDRVSAGESKIGYGNHDESLGGPFQQDATPVFTWQG KERTYFRVETKDTYTGKGWIETDTGMSYQLSNGKVENLWFDHKVATERRTVRVKVDKH YGYNHLMYPIGAETIQPKQAVSLEMNGNTEQISPISEQAGEIRNMGNYTVTYNSPVYK LDELRKVKVRKNSEEYTFSDRYMQLPDSLPERVRTLAIKLTQDHDNMFDKVKAVEDYL GSNAFTYETENVTIPKNDEDYVDQFLFETKMGYCDNFSSAMVVLLRSAGIPARWVKGY TSGEYKEAGNKNGSIYEVTNNNAHSWVEVYFPEQGWVTFEPTKGFTNPAQFTSSDTKD SGSDSSSSPKKAKEKQKEEKKQPQKEEKQKEKREPAVSKKPSASHTNAGAGLYAALAV LAVLLVAAVLLYVFRSLWIPVFAVRKLKRRSDQHAFFEAYGALLKQLKRKGLPKRDSE TLRDYAKRIDEKYDIEDMSKLTLSYERALYRNEDSSALWNDSRELWENLIKRRWS*" gene 690364..692577 /gene="yebA" /locus_tag="BSU_06350" /old_locus_tag="BSU06350" promotor_-35 692572..692579 /Source="Nicolas_upshift_promotors" /id="U492" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.912087912087912" /psig="0.999000999001" /xcortree=2555 /SigmaFactorBS="aaatttaattaaaagaagatggTCTTGACCgcttatcgacgt gtTGTTAGAATTAGTGAATATTatcggagtctgggagcgagttggcctgactccggca a" /listShort="S227, guaA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 692594..692613 /Source="Nicolas_upshift_promotors" /id="U492" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.912087912087912" /psig="0.999000999001" /xcortree=2555 /SigmaFactorBS="aaatttaattaaaagaagatggTCTTGACCgcttatcgacgt gtTGTTAGAATTAGTGAATATTatcggagtctgggagcgagttggcctgactccggca a" /listShort="S227, guaA" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 692610..692739 /Source="Nicolas_S_feature" /locus_tag="new_692610_692739" /HighExp="G180, Oxctl, G135, LBGexp, G150, Paraq, C30, LPh, MG 25, C90" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.63292099999999996" /TUshortSig="SigA" /TUshortPSig="0.999" /TUlongSig="SigA" /TUlongPSig=1 /label="S227" upshifts 692610 /Source="Nicolas_upshifts" /id="U492" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.912087912087912" /psig="0.999000999001" /xcortree=2555 /SigmaFactorBS="aaatttaattaaaagaagatggTCTTGACCgcttatcgacgt gtTGTTAGAATTAGTGAATATTatcggagtctgggagcgagttggcctgactccggca a" /listShort="S227, guaA" /GFF_Attribute="listLong" CDS 692740..694281 /gene="guaA" /locus_tag="BSU_06360" /old_locus_tag="BSU06360" /EC_number="6.3.5.2" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 1312531, 21856856; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="GMP synthetase" /protein_id="NP_388517.2" /db_xref="EnsemblGenomes-Gn:BSU06360" /db_xref="EnsemblGenomes-Tr:CAB12455" /db_xref="GOA:P29727" /db_xref="InterPro:IPR001674" /db_xref="InterPro:IPR004739" /db_xref="InterPro:IPR014729" /db_xref="InterPro:IPR017926" /db_xref="InterPro:IPR022310" /db_xref="InterPro:IPR022955" /db_xref="InterPro:IPR025777" /db_xref="InterPro:IPR029062" /db_xref="SubtiList:BG10647" /db_xref="UniProtKB/Swiss-Prot:P29727" /translation="MTKLVNEMILVLDFGSQYNQLITRRIREFGVYSELHPHTLTAEE IKKMNPKGIILSGGPNSVYDENSFRCDEKIFELDIPVLGICYGMQLMTHYLGGKVEAA SQREYGKANIRIEGTPDLFRDLPNEQVVWMSHGDLVVEVPEGFTVDATSHHCPNSAMS KADKKWYGVQFHPEVRHSEYGNDLLKNFVFGVCECEGEWSMENFIEIEMQKIRETVGD KQVLCALSGGVDSSVVAVLIHKAIGDQLTCIFVDHGLLRKGEAEGVMKTFSEGFNMNV IKVDAKDRFLNKLKGVSDPEQKRKIIGNEFIYVFDDEADKLKGIDYLAQGTLYTDIIE SGTATAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRALGTELGIPDEIVWRQPFP GPGLGIRVLGEVTEEKLEIVRESDAILREEIANHGLERDIWQYFTVLPDIRSVGVMGD ARTYDYTIGIRAVTSIDGMTSDWARIPWDVLEVISTRIVNEVKHINRVVYDITSKPPA TIEWE*" gene 692740..694281 /gene="guaA" /locus_tag="BSU_06360" /old_locus_tag="BSU06360" downshifts 694267 /Source="Nicolas_upshifts" /id="D312" /incds=0 /nref=247 /ntot=268 /MaxReadThrough="2.12151" /MaxDrop="7.3702" /score="22.5795134" /energy="-18.5" /TU="NA" /idTUdmin="U492" /TUdmin=0 /isTUend="TRUE" promotor_-35 694388..694392 /Source="Nicolas_upshift_promotors" /id="U493" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.767232767232767" /psig=1 /xcortree=2631 /SigmaFactorBS="cgattttgcgcgactattgttcgctttttgTATTGttttttc aaaatgaaCTTGGTACAATAGACACAGAaatcaaataagatgaattcgtataatcgcg g" /listShort="NA, pbuG" /listLong="S228, yebC" /label="promotor_-35" promotor_-10 694408..694427 /Source="Nicolas_upshift_promotors" /id="U493" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.767232767232767" /psig=1 /xcortree=2631 /SigmaFactorBS="cgattttgcgcgactattgttcgctttttgTATTGttttttc aaaatgaaCTTGGTACAATAGACACAGAaatcaaataagatgaattcgtataatcgcg g" /listShort="NA, pbuG" /listLong="S228, yebC" /label="promotor_-10" upshifts 694418 /Source="Nicolas_upshifts" /id="U493" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.767232767232767" /psig=1 /xcortree=2631 /SigmaFactorBS="cgattttgcgcgactattgttcgctttttgTATTGttttttc aaaatgaaCTTGGTACAATAGACACAGAaatcaaataagatgaattcgtataatcgcg g" /listShort="NA, pbuG" /listLong="S228, yebC" misc_RNA 694425..694527 /gene="gswC" /locus_tag="BSU_misc_RNA_9" /product="guanine riboswitch" /experiment="publication(s) with functional evidences, PMID:12787499, 15549109, 18072940, 19603494, 20022916, 20200045, 20204714, 21439477, 25023436, 27941758" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12787499, 15549109, 18072940, 19603494, 20022916, 20200045, 20204714, 21439477, 25023436, 27941758; Product type n: RNA" gene 694425..694527 /gene="gswC" /locus_tag="BSU_misc_RNA_9" downshifts 694553 /Source="Nicolas_upshifts" /id="D313" /incds=0 /nref=11 /ntot=56 /MaxReadThrough="8.01916" /MaxDrop="4.7859" /score="24.3821572" /energy="-11.3" /TU="U493" /idTUdmin="U492" /TUdmin=286 /isTUend="FALSE" CDS 694662..695984 /gene="pbuG" /locus_tag="BSU_06370" /old_locus_tag="BSU06370" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:3110131, 11591660, 12923093, 15849754, 16850406, 19446032" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 3110131, 11591660, 12923093, 15849754, 16850406, 19446032; Product type t : transporter" /codon_start=1 /transl_table=11 /product="hypoxanthine/guanine permease" /protein_id="NP_388518.1" /db_xref="EnsemblGenomes-Gn:BSU06370" /db_xref="EnsemblGenomes-Tr:CAB12456" /db_xref="GOA:O34987" /db_xref="InterPro:IPR006043" /db_xref="InterPro:IPR026033" /db_xref="SubtiList:BG12811" /db_xref="UniProtKB/Swiss-Prot:O34987" /translation="MKTFFQFDELGTSYRNEIIGGLTTFLSMAYILFVNPITLALESV KDFPEALRIDQGAVFTATALASAAGCILMGLIARYPIAIAPGMGLNAFFAFSVVLGMG ISWQAALSGVFISGLIFVALSLTGFREKIINAIPPELKLAVGAGIGLFITFVGLQGSG IITANPSTLVTIGNIHSGPVLLTIFGVIVTVILMVLRVNAGVFIGMLLTAVAGMIFGL VPVPTQIIGSVPSLAPTFGQAWIHLPDIFSVQMLIVILTFLFVGFFDTAGTLVAVATQ AGLMKENKLPRAGRALLADSSSIVIGAVLGTSTTTSYVESSSGVAAGARSGFAAIVTG ILFLLATFFSPLLSVVTSNVTAPALIIVGALMVAPLGKIAWDKFEVAVPAFLTMIMMP LTYSIATGIAIGFIFYPITMVCKGKAKEVHPIMYGLFVVFILYFIFLK*" gene 694662..695984 /gene="pbuG" /locus_tag="BSU_06370" /old_locus_tag="BSU06370" downshifts 695962 /Source="Nicolas_upshifts" /id="D314" /incds=0 /nref=47 /ntot=153 /MaxReadThrough="4.18958" /MaxDrop="4.86237" /score="42.0241443" /energy="-13.4" /TU="U493" /idTUdmin="U493" /TUdmin="-86" /isTUend="FALSE" downshifts 696005 /Source="Nicolas_upshifts" /id="D315" /incds=0 /nref=1 /ntot=29 /MaxReadThrough="3.09696" /MaxDrop="3.87785" /score="42.0241443" /energy="-13.4" /TU="U493" /idTUdmin="U493" /TUdmin="-43" /isTUend="FALSE" promotor_-35 696034..696043 /Source="Nicolas_upshift_promotors" /id="U494" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=1642 /SigmaFactorBS="aaccagctgcactggcagctggtttttttgttgcaaaagaTA AAACCATTtcatacgatataCCGTCATGTAGATGTGccgccatgctttacttaaatgg a" /listShort="S228, yebC" /GFF_Attribute="listLong" /label="promotor_-35" S_feature 696054..696194 /Source="Nicolas_S_feature" /locus_tag="new_696054_696194" /HighExp="T1.30H, T1.0H, T2.0H, T0.30H, B60, T2.30H, T-0.40H, T0.0H, T3.0H, T-1.10H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigWXY" /TUshortPSig="0.998" /TUlongSig="SigA" /TUlongPSig=1 /label="S228" upshifts 696054 /Source="Nicolas_upshifts" /id="U494" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=1642 /SigmaFactorBS="aaccagctgcactggcagctggtttttttgttgcaaaagaTA AAACCATTtcatacgatataCCGTCATGTAGATGTGccgccatgctttacttaaatgg a" /listShort="S228, yebC" /GFF_Attribute="listLong" promotor_-10 696056..696071 /Source="Nicolas_upshift_promotors" /id="U494" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=1642 /SigmaFactorBS="aaccagctgcactggcagctggtttttttgttgcaaaagaTA AAACCATTtcatacgatataCCGTCATGTAGATGTGccgccatgctttacttaaatgg a" /listShort="S228, yebC" /GFF_Attribute="listLong" /label="promotor_-10" CDS 696195..696998 /gene="yebC" /locus_tag="BSU_06380" /old_locus_tag="BSU06380" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406, 22720735; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative integral inner membrane protein" /protein_id="NP_388519.2" /db_xref="EnsemblGenomes-Gn:BSU06380" /db_xref="EnsemblGenomes-Tr:CAB12457" /db_xref="GOA:O34341" /db_xref="SubtiList:BG12812" /db_xref="UniProtKB/Swiss-Prot:O34341" /translation="MTEERKETFEEEINQSERIDADEEPLSRMSRKASRQSKQKQKQK QKPRQERGESTVKDKLASVWAAINRYCGFAFSILKSPAKTVVTDGFSHYKYGLISMLI FSIIFSIGNWFQLKASWNRPLGFGERHHAFYDGFLVVLVYLLIFFAVMVFAIWAVSRY MMKQKVTFREAAAVLGSLLVPVIAVSILWLIFAIVNIPMLTVLFTVLILFSIFFIIAL YVQRVYQAAQDAPIDYIYCVFAVVAIALLFTAVTWPFISEYITASLIPL*" gene 696195..696998 /gene="yebC" /locus_tag="BSU_06380" /old_locus_tag="BSU06380" downshifts 696983 /Source="Nicolas_upshifts" /id="D316" /incds=0 /nref=218 /ntot=263 /MaxReadThrough="1.47691" /MaxDrop="7.03926" /score="33.0377004" /energy="-10.7" /TU="NA" /idTUdmin="U494" /TUdmin=0 /isTUend="TRUE" promotor_-35 697066..697073 /Source="Nicolas_upshift_promotors" /id="U495" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.524475524475524" /psig=1 /xcortree=527 /SigmaFactorBS="tgtcacactttttacaaatatatctaaaaaacaTAGTTGATt tgtaggattaacCCGTGTATGATGGGGAAAATgctgaaaacgtccagcgcaaaaacct t" /listShort="S229, yebD" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 697087..697106 /Source="Nicolas_upshift_promotors" /id="U495" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.524475524475524" /psig=1 /xcortree=527 /SigmaFactorBS="tgtcacactttttacaaatatatctaaaaaacaTAGTTGATt tgtaggattaacCCGTGTATGATGGGGAAAATgctgaaaacgtccagcgcaaaaacct t" /listShort="S229, yebD" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 697093..697156 /Source="Nicolas_S_feature" /locus_tag="new_697093_697156" /HighExp="B60, S2, S7, S8, Lbstat, nit, S4, BC, BT, M0t90" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S229" upshifts 697093 /Source="Nicolas_upshifts" /id="U495" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.524475524475524" /psig=1 /xcortree=527 /SigmaFactorBS="tgtcacactttttacaaatatatctaaaaaacaTAGTTGATt tgtaggattaacCCGTGTATGATGGGGAAAATgctgaaaacgtccagcgcaaaaacct t" /listShort="S229, yebD" /GFF_Attribute="listLong" CDS 697157..697324 /gene="yebD" /locus_tag="BSU_06390" /old_locus_tag="BSU06390" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="NP_388520.3" /db_xref="EnsemblGenomes-Gn:BSU06390" /db_xref="EnsemblGenomes-Tr:CAB12458" /db_xref="InterPro:IPR025072" /db_xref="SubtiList:BG12813" /db_xref="UniProtKB/Swiss-Prot:O34904" /translation="MADVLRRAINQKKQFLKTKLLLSEFYQGRGEQLADYTLSELEKE YKSLQKMKKEI*" gene 697157..697324 /gene="yebD" /locus_tag="BSU_06390" /old_locus_tag="BSU06390" downshifts 697331 /Source="Nicolas_upshifts" /id="D317" /incds=0 /nref=64 /ntot=163 /MaxReadThrough="2.85884" /MaxDrop="5.66286" /score="29.2645456" /energy="-9" /TU="NA" /idTUdmin="U495" /TUdmin="-2" /isTUend="TRUE" promotor_-35 697375..697381 /Source="Nicolas_upshift_promotors" /id="U496" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.966033966033966" /psig="0.966033966033966" /xcortree=744 /SigmaFactorBS="aggtgagtctgctgaaaagcgggcttttttgttttgATTTTG AaaaggcgagaaagaGGGTAAACTACTACTGTTCaacacataaaagcgtgtcgaaata t" /listShort="S230, yebE, yebG, NA, S231" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 697396..697414 /Source="Nicolas_upshift_promotors" /id="U496" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.966033966033966" /psig="0.966033966033966" /xcortree=744 /SigmaFactorBS="aggtgagtctgctgaaaagcgggcttttttgttttgATTTTG AaaaggcgagaaagaGGGTAAACTACTACTGTTCaacacataaaagcgtgtcgaaata t" /listShort="S230, yebE, yebG, NA, S231" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 697399..697485 /Source="Nicolas_S_feature" /locus_tag="new_697399_697485" /HighExp="Etha, Gly, M9-stat, Sw, B60, S4, S6, LPhT, S3, S8" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigB" /TUshortPSig="0.966" /TUlongSig="NA" /TUlongPSig="NA" /label="S230" upshifts 697399 /Source="Nicolas_upshifts" /id="U496" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.966033966033966" /psig="0.966033966033966" /xcortree=744 /SigmaFactorBS="aggtgagtctgctgaaaagcgggcttttttgttttgATTTTG AaaaggcgagaaagaGGGTAAACTACTACTGTTCaacacataaaagcgtgtcgaaata t" /listShort="S230, yebE, yebG, NA, S231" /GFF_Attribute="listLong" promotor_-35 697464..697471 /Source="Nicolas_upshift_promotors" /id="U497" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.876123876123876" /psig="0.999000999001" /xcortree=2463 /SigmaFactorBS="cgtgtcgaaatattttgcttaagcttacgggcgaagcTGATT GTAaacggctcatttcTCTAGTAGAATATGAATGCTttgtgcaagctgaagagtaggg g" /listShort="yebE, yebG" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 697485..697504 /Source="Nicolas_upshift_promotors" /id="U497" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.876123876123876" /psig="0.999000999001" /xcortree=2463 /SigmaFactorBS="cgtgtcgaaatattttgcttaagcttacgggcgaagcTGATT GTAaacggctcatttcTCTAGTAGAATATGAATGCTttgtgcaagctgaagagtaggg g" /listShort="yebE, yebG" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 697487 /Source="Nicolas_upshifts" /id="U497" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.876123876123876" /psig="0.999000999001" /xcortree=2463 /SigmaFactorBS="cgtgtcgaaatattttgcttaagcttacgggcgaagcTGATT GTAaacggctcatttcTCTAGTAGAATATGAATGCTttgtgcaagctgaagagtaggg g" /listShort="yebE, yebG" /GFF_Attribute="listLong" CDS 697538..698092 /gene="yebE" /locus_tag="BSU_06400" /old_locus_tag="BSU06400" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_388521.2" /db_xref="EnsemblGenomes-Gn:BSU06400" /db_xref="EnsemblGenomes-Tr:CAB12459" /db_xref="GOA:O34624" /db_xref="InterPro:IPR019264" /db_xref="InterPro:IPR022930" /db_xref="SubtiList:BG12814" /db_xref="UniProtKB/Swiss-Prot:O34624" /translation="MMQTILSNGIAMVLIILIINIVYVSFFTIRMILTLKGQRYLAAG ISTIEILVYVTGLSLVLDNLDQIQNVIAYALGYGLGVIVGMKIEEKLALGYIMVNVIT KELDLDLPKQLREKGYGVTNWVAGGLEGDRTALQILTPRRYELQLYDTIKTLDSKAFI IAYEPKTIHGGFWVKAVKKRRIKE*" gene 697538..698092 /gene="yebE" /locus_tag="BSU_06400" /old_locus_tag="BSU06400" CDS 698092..698289 /gene="yebG" /locus_tag="BSU_06410" /old_locus_tag="BSU06410" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_388523.1" /db_xref="EnsemblGenomes-Gn:BSU06410" /db_xref="EnsemblGenomes-Tr:CAB12461" /db_xref="InterPro:IPR025930" /db_xref="SubtiList:BG12816" /db_xref="UniProtKB/Swiss-Prot:O34700" /translation="MAKPKKKKFEVTEQQTIDAVLQQMKEEGYLPVRRMEEPIFMEKK ENGSIQIVPCGKKIVFEGKLI*" gene 698092..698289 /gene="yebG" /locus_tag="BSU_06410" /old_locus_tag="BSU06410" downshifts 698279 /Source="Nicolas_upshifts" /id="D318" /incds=0 /nref=2 /ntot=91 /MaxReadThrough="2.80904" /MaxDrop="2.65424" /score="17.462689" /energy="-17.6" /TU="U496" /idTUdmin="U497" /TUdmin=0 /isTUend="TRUE" promotor_-35 698335..698342 /Source="Nicolas_upshift_promotors" /id="U498" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.97902097902098" /psig=1 /xcortree=2428 /SigmaFactorBS="attagtagaatgaatttttgtatcgttcgataatatCGTTGA CAttatccatgtccgtTGTTAAGATAAACATGAAATcaaaacacgacctcatataatc t" /listShort="NA, S231, purE, purK, purB, purC, purS, purQ, purL, purF, S232, purM, purN, purH, purD" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 698357..698376 /Source="Nicolas_upshift_promotors" /id="U498" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.97902097902098" /psig=1 /xcortree=2428 /SigmaFactorBS="attagtagaatgaatttttgtatcgttcgataatatCGTTGA CAttatccatgtccgtTGTTAAGATAAACATGAAATcaaaacacgacctcatataatc t" /listShort="NA, S231, purE, purK, purB, purC, purS, purQ, purL, purF, S232, purM, purN, purH, purD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 698359 /Source="Nicolas_upshifts" /id="U498" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.97902097902098" /psig=1 /xcortree=2428 /SigmaFactorBS="attagtagaatgaatttttgtatcgttcgataatatCGTTGA CAttatccatgtccgtTGTTAAGATAAACATGAAATcaaaacacgacctcatataatc t" /listShort="NA, S231, purE, purK, purB, purC, purS, purQ, purL, purF, S232, purM, purN, purH, purD" /GFF_Attribute="listLong" misc_RNA 698369..698471 /gene="gswD" /locus_tag="BSU_misc_RNA_10" /product="guanine riboswitch" /experiment="publication(s) with functional evidences, PMID:12787499, 15549109, 18072940, 19603494, 20022916, 20200045, 20204714, 21439477, 25023436, 27941758" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12787499, 15549109, 18072940, 19603494, 20022916, 20200045, 20204714, 21439477, 25023436, 27941758; Product type n: RNA" gene 698369..698471 /gene="gswD" /locus_tag="BSU_misc_RNA_10" S_feature 698472..698611 /Source="Nicolas_S_feature" /locus_tag="new_698472_698611" /HighExp="MG 10, MG 15, MG t5, BMM, MG 25, MG 5, HPh, GM 45, GM 90, M9-exp" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigB" /TUshortPSig="1, 0.966" /TUlongSig="NA" /TUlongPSig="NA" /label="S231" CDS 698612..699100 /gene="purE" /locus_tag="BSU_06420" /old_locus_tag="BSU06420" /EC_number="5.4.99.18" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1c: Function from experimental evidences in the studied genus; PubMedId: 12787499, 16138311, 9683488; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="N5-carboxyaminoimidazole ribonucleotide mutase" /protein_id="NP_388524.1" /db_xref="EnsemblGenomes-Gn:BSU06420" /db_xref="EnsemblGenomes-Tr:CAB12462" /db_xref="GOA:P12044" /db_xref="InterPro:IPR000031" /db_xref="InterPro:IPR024694" /db_xref="InterPro:IPR033747" /db_xref="InterPro:IPR035893" /db_xref="SubtiList:BG10700" /db_xref="UniProtKB/Swiss-Prot:P12044" /translation="MQPLVGIIMGSTSDWETMKHACDILDELNVPYEKKVVSAHRTPD FMFEYAETARERGIKVIIAGAGGAAHLPGMTAAKTTLPVIGVPVQSKALNGMDSLLSI VQMPGGVPVATTSIGKAGAVNAGLLAAQILSAFDEDLARKLDERRENTKQTVLESSDQ LV*" gene 698612..699100 /gene="purE" /locus_tag="BSU_06420" /old_locus_tag="BSU06420" CDS 699093..700235 /gene="purK" /locus_tag="BSU_06430" /old_locus_tag="BSU06430" /EC_number="6.3.4.18" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1c: Function from experimental evidences in the studied genus; PubMedId: 8998996, 9683488, 21931218, 25372694; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="N5-carboxyaminoimidazole ribonucleotide synthase" /protein_id="NP_388525.2" /db_xref="EnsemblGenomes-Gn:BSU06430" /db_xref="EnsemblGenomes-Tr:CAB12463" /db_xref="GOA:P12045" /db_xref="InterPro:IPR003135" /db_xref="InterPro:IPR005875" /db_xref="InterPro:IPR006115" /db_xref="InterPro:IPR011054" /db_xref="InterPro:IPR011761" /db_xref="InterPro:IPR013815" /db_xref="InterPro:IPR016185" /db_xref="SubtiList:BG10701" /db_xref="UniProtKB/Swiss-Prot:P12045" /translation="MSKQIIYPGAVIGIIGGGQLGKMMAVSAKQMGYKVAVVDPVKDS PCGQVADVEITAHYNDREAIRKLAEISDIITYEFENIDYDALHWLKDHAYLPQGSELL LITQNRETEKKAIQSAGCEVAPYSIVKTKNELKQAVQELRLPAVLKTCRGGYDGKGQF VIKEEAQMEQAAALLEHGTCILESWVSFKMELSVIVVRSVNGEISTFPTAENIHHNNI LFQSIVPARVEKGIQQKAADLAVKLADELNLVGPLAVEMFLTEDGELLVNELAPRPHN SGHYTLDLCETSQFEQHIRAVCGLPLGKTDLLKPGMMVNLLGDEVKLVEEDPELLKEA KLYIYGKHEIKKGRKMGHITFMKQPEDEWIQEITNKWMNRDGGQAE*" gene 699093..700235 /gene="purK" /locus_tag="BSU_06430" /old_locus_tag="BSU06430" CDS 700232..701527 /gene="purB" /locus_tag="BSU_06440" /old_locus_tag="BSU06440" /EC_number="4.3.2.2" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 9622500, 9683488, 9890879, 11063569, 12787499; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="adenylosuccinate lyase" /protein_id="NP_388526.1" /db_xref="EnsemblGenomes-Gn:BSU06440" /db_xref="EnsemblGenomes-Tr:CAB12464" /db_xref="GOA:P12047" /db_xref="InterPro:IPR000362" /db_xref="InterPro:IPR004769" /db_xref="InterPro:IPR008948" /db_xref="InterPro:IPR019468" /db_xref="InterPro:IPR020557" /db_xref="InterPro:IPR022761" /db_xref="InterPro:IPR024083" /db_xref="PDB:1F1O" /db_xref="SubtiList:BG10702" /db_xref="UniProtKB/Swiss-Prot:P12047" /translation="MIERYSRPEMSAIWTDENRFQAWLEVEILACEAWAELGVIPKED VKVMRENASFDINRILEIEKDTRHDVVAFTRAVSESLGEERKWVHYGLTSTDVVDTAL SYLLKQANDILLKDLERFVDIIKEKAKEHKYTVMMGRTHGVHAEPTTFGLKLALWHEE MKRNLERFKQAKAGIEVGKISGAVGTYANIDPFVEQYVCEKLGLKAAPISTQTLQRDR HADYMATLALIATSIEKFAVEIRGLQKSETREVEEFFAKGQKGSSAMPHKRNPIGSEN MTGMARVIRGYMMTAYENVPLWHERDISHSSAERIILPDATIALNYMLNRFSNIVKNL TVFPENMKRNMDRTLGLIYSQRVLLALIDTGLTREEAYDTVQPKAMEAWEKQVPFREL VEAEEKITSRLSPEKIADCFDYNYHLKNVDLIFERLGLA*" gene 700232..701527 /gene="purB" /locus_tag="BSU_06440" /old_locus_tag="BSU06440" promotor_-10 complement(700537..700556) /Source="Nicolas_upshift_promotors" /id="U499" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.791208791208791" /psig="0.993006993006993" /xcortree=1708 /SigmaFactorBS="tttcgctttttcttttataatgtcaacaaatctctcaagaTC CTTGAGcaaaatatcgtttgCCTGTTTTAATAAGTAGGAAagagccgtatcaacaacg t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(700558) /Source="Nicolas_upshifts" /id="U499" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.791208791208791" /psig="0.993006993006993" /xcortree=1708 /SigmaFactorBS="tttcgctttttcttttataatgtcaacaaatctctcaagaTC CTTGAGcaaaatatcgtttgCCTGTTTTAATAAGTAGGAAagagccgtatcaacaacg t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(700571..700578) /Source="Nicolas_upshift_promotors" /id="U499" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.791208791208791" /psig="0.993006993006993" /xcortree=1708 /SigmaFactorBS="tttcgctttttcttttataatgtcaacaaatctctcaagaTC CTTGAGcaaaatatcgtttgCCTGTTTTAATAAGTAGGAAagagccgtatcaacaacg t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" CDS 701601..702326 /gene="purC" /locus_tag="BSU_06450" /old_locus_tag="BSU06450" /EC_number="6.3.2.6" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1c: Function from experimental evidences in the studied genus; PubMedId: 2495272, 9683488, 10784038, 12787499, 26118696; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="phosphoribosylaminoimidazole succinocarboxamide synthetase" /protein_id="NP_388527.1" /db_xref="EnsemblGenomes-Gn:BSU06450" /db_xref="EnsemblGenomes-Tr:CAB12465" /db_xref="GOA:P12046" /db_xref="InterPro:IPR001636" /db_xref="InterPro:IPR018236" /db_xref="InterPro:IPR028923" /db_xref="InterPro:IPR033934" /db_xref="SubtiList:BG10703" /db_xref="UniProtKB/Swiss-Prot:P12046" /translation="MNIVKNELLYEGKAKKIYKTDDENTLYVVYKDSATAFNGEKKAE ISGKGRLNNEISSLIFKHLHAKGINNHFIERISETEQLIKKVTIVPLEVVVRNVVAGS MSKRLGIPEGTELEQPIIEFYYKDDALGDPLITEDHIWLLKAATPEQVETIKSITTIV NEELQSIFDDCHVRLIDFKLEFGLDAEGQVLLADEISPDTCRLWDKETNEKLDKDLFR RNLGSLTDAYEEIFNRLGGIHHV*" gene 701601..702326 /gene="purC" /locus_tag="BSU_06450" /old_locus_tag="BSU06450" CDS 702319..702573 /gene="purS" /locus_tag="BSU_06460" /old_locus_tag="BSU06460" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:10784038, 12787499" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10784038, 12787499; Product type f: factor" /codon_start=1 /transl_table=11 /product="factor required for phosphoribosylformylglycinamidine synthetase activity" /protein_id="NP_388528.1" /db_xref="EnsemblGenomes-Gn:BSU06460" /db_xref="EnsemblGenomes-Tr:CAB12466" /db_xref="GOA:P12049" /db_xref="InterPro:IPR003850" /db_xref="InterPro:IPR036604" /db_xref="PDB:1T4A" /db_xref="PDB:1TWJ" /db_xref="SubtiList:BG10704" /db_xref="UniProtKB/Swiss-Prot:P12049" /translation="MYKVKVYVSLKESVLDPQGSAVQHALHSMTYNEVQDVRIGKYME LTIEKSDRDLDVLVKEMCEKLLANTVIEDYRYEVEEVVAQ*" gene 702319..702573 /gene="purS" /locus_tag="BSU_06460" /old_locus_tag="BSU06460" CDS 702570..703253 /gene="purQ" /locus_tag="BSU_06470" /old_locus_tag="BSU06470" /EC_number="6.3.5.3" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:12787499, 15301530, 15301532, 10784038, 9683488" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12787499, 15301530, 15301532, 10784038, 9683488; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="phosphoribosylformylglycinamidine synthetase subunit I" /protein_id="NP_388529.1" /db_xref="EnsemblGenomes-Gn:BSU06470" /db_xref="EnsemblGenomes-Tr:CAB12467" /db_xref="GOA:P12041" /db_xref="InterPro:IPR010075" /db_xref="InterPro:IPR017926" /db_xref="InterPro:IPR029062" /db_xref="SubtiList:BG10706" /db_xref="UniProtKB/Swiss-Prot:P12041" /translation="MKFAVIVLPGSNCDIDMYHAVKDELGHEVEYVWHEETSLDGFDG VLIPGGFSYGDYLRCGAIARFANIMPAVKQAAAEGKPVLGVCNGFQILQELGLLPGAM RRNKDLKFICRPVELIVQNDETLFTASYEKGESITIPVAHGEGNFYCDDETLATLKEN NQIAFTYGSNINGSVSDIAGVVNEKGNVLGMMPHPERAVDELLGSADGLKLFQSIVKN WRETHVTTA*" gene 702570..703253 /gene="purQ" /locus_tag="BSU_06470" /old_locus_tag="BSU06470" CDS 703237..705465 /gene="purL" /locus_tag="BSU_06480" /old_locus_tag="BSU06480" /EC_number="6.3.5.3" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:12787499, 15301532, 10784038, 9683488, 21671997" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12787499, 15301532, 10784038, 9683488, 21671997; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="phosphoribosylformylglycinamidine synthetase subunit II" /protein_id="NP_388530.2" /db_xref="EnsemblGenomes-Gn:BSU06480" /db_xref="EnsemblGenomes-Tr:CAB12468" /db_xref="GOA:P12042" /db_xref="InterPro:IPR010074" /db_xref="InterPro:IPR010918" /db_xref="InterPro:IPR016188" /db_xref="InterPro:IPR036676" /db_xref="InterPro:IPR036921" /db_xref="SubtiList:BG10705" /db_xref="UniProtKB/Swiss-Prot:P12042" /translation="MSLLLEPSKEQIKEEKLYQQMGVSDDEFALIESILGRLPNYTEI GIFSVMWSEHCSYKNSKPILRKFPTSGERVLQGPGEGAGIVDIGDNQAVVFKIESHNH PSALEPYQGAATGVGGIIRDVFSMGARPIAVLNSLRFGELTSPRVKYLFEEVVAGIAG YGNCIGIPTVGGEVQFDSSYEGNPLVNAMCVGLINHEDIKKGQAKGVGNTVMYVGAKT GRDGIHGATFASEEMSDSSEEKRSAVQVGDPFMEKLLLEACLEVIQCDALVGIQDMGA AGLTSSSAEMASKAGSGIEMNLDLIPQRETGMTAYEMMLSESQERMLLVIERGREQEI IDIFDKYDLEAVSVGHVTDDKMLRLTHKGEVVCELPVDALAEEAPVYHKPSQEPAYYR EFLETDVPAPQIEDANEMLKALLQQPTIASKEWVYDQYDYMVRTNTVVAPGSDAGVLR IRGTKKALAMTTDCNARYLYLDPEVGGKIAVAEAARNIICSGAEPLAVTDNLNFGNPE KPEIFWQIEKAADGISEACNVLSTPVIGGNVSLYNESNGTAIYPTPVIGMVGLIEDTA HITTQHFKQAGDLVYVIGETKPEFAGSELQKMTEGRIYGKAPQIDLDVELSRQKALLD AIKKGFVQSAHDVSEGGLGVAIAESVMTTENLGANVTVEGEAALLFSESQSRFVVSVK KEHQAAFEATVKDAVHIGEVTADGILAIQNQDGQQMIHAQTKELERVWKGAIPCLLKS KA*" gene 703237..705465 /gene="purL" /locus_tag="BSU_06480" /old_locus_tag="BSU06480" downshifts complement(703485) /Source="Nicolas_upshifts" /id="D319" /incds=1 /nref=1 /ntot=47 /MaxReadThrough="0.69202" /MaxDrop="3.99287" /score="-6.56256716" /energy="-16.7" /TU="NA" /idTUdmin="U499" /TUdmin="-3147" /isTUend="FALSE" CDS 705441..706871 /gene="purF" /locus_tag="BSU_06490" /old_locus_tag="BSU06490" /EC_number="2.4.2.14" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:9683488, 10049369, 12787499, 16321950, 17981983" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9683488, 10049369, 12787499, 16321950, 17981983; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="glutamine phosphoribosylpyrophosphate amidotransferase" /protein_id="NP_388531.2" /db_xref="EnsemblGenomes-Gn:BSU06490" /db_xref="EnsemblGenomes-Tr:CAB12469" /db_xref="GOA:P00497" /db_xref="InterPro:IPR000836" /db_xref="InterPro:IPR005854" /db_xref="InterPro:IPR017932" /db_xref="InterPro:IPR029055" /db_xref="InterPro:IPR029057" /db_xref="InterPro:IPR035584" /db_xref="PDB:1AO0" /db_xref="PDB:1GPH" /db_xref="SubtiList:BG10707" /db_xref="UniProtKB/Swiss-Prot:P00497" /translation="MLAEIKGLNEECGVFGIWGHEEAPQITYYGLHSLQHRGQEGAGI VATDGEKLTAHKGQGLITEVFQNGELSKVKGKGAIGHVRYATAGGGGYENVQPLLFRS QNNGSLALAHNGNLVNATQLKQQLENQGSIFQTSSDTEVLAHLIKRSGHFTLKDQIKN SLSMLKGAYAFLIMTETEMIVALDPNGLRPLSIGMMGDAYVVASETCAFDVVGATYLR EVEPGEMLIINDEGMKSERFSMNINRSICSMEYIYFSRPDSNIDGINVHSARKNLGKM LAQESAVEADVVTGVPDSSISAAIGYAEATGIPYELGLIKNRYVGRTFIQPSQALREQ GVRMKLSAVRGVVEGKRVVMVDDSIVRGTTSRRIVTMLREAGATEVHVKISSPPIAHP CFYGIDTSTHEELIASSHSVEEIRQEIGADTLSFLSVEGLLKGIGRKYDDSNCGQCLA CFTGKYPTEIYQDTVLPHVKEAVLTK*" gene 705441..706871 /gene="purF" /locus_tag="BSU_06490" /old_locus_tag="BSU06490" S_feature 706872..706972 /Source="Nicolas_S_feature" /locus_tag="new_706872_706972" /HighExp="MG 15, MG 25, MG 10, MG 5, aero, S0, MG t5, Gly, LPh, GM 90" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S232" CDS 706973..708013 /gene="purM" /locus_tag="BSU_06500" /old_locus_tag="BSU06500" /EC_number="6.3.3.1" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 9683488, 10508786, 12787499, 16321950; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="phosphoribosylaminoimidazole synthetase" /protein_id="NP_388532.2" /db_xref="EnsemblGenomes-Gn:BSU06500" /db_xref="EnsemblGenomes-Tr:CAB12470" /db_xref="GOA:P12043" /db_xref="InterPro:IPR004733" /db_xref="InterPro:IPR010918" /db_xref="InterPro:IPR016188" /db_xref="InterPro:IPR036676" /db_xref="InterPro:IPR036921" /db_xref="SubtiList:BG10708" /db_xref="UniProtKB/Swiss-Prot:P12043" /translation="MSEAYKNAGVDIEAGYEAVKRMKKHVERTKRLGVMGSLGGFGGM FDLSELSYQKPVLISGTDGVGTKLKLAFSMDKHDTIGVDAVAMCVNDVLAQGAEPLFF LDYLAVGKADPVKIEQIVQGVAEGCEQSGSALVGGETAEMPGLYTADEYDIAGFSVGV AEKDEIVTGEKIEEGHLLIGLSSSGLHSNGFSLVRKVLLDDAELDLDTTYEPFERPLG EELLEPTRIYVKPVLAAVKSGKIDGMAHVTGGGFIENIPRMLPEGLSAEIDHGSWPIP PIFSFLQEYGKLKEEDMFNVFNMGIGFVLAVKEEHLTDVIGTLESHGEKAYLIGRVKK GEGVTFGGAALS*" gene 706973..708013 /gene="purM" /locus_tag="BSU_06500" /old_locus_tag="BSU06500" CDS 708010..708597 /gene="purN" /locus_tag="BSU_06510" /old_locus_tag="BSU06510" /EC_number="2.1.2.2" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 9683488, 10569930, 12787499, 19574646; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="phosphoribosylglycinamide formyltransferase" /protein_id="NP_388533.2" /db_xref="EnsemblGenomes-Gn:BSU06510" /db_xref="EnsemblGenomes-Tr:CAB12471" /db_xref="GOA:P12040" /db_xref="InterPro:IPR001555" /db_xref="InterPro:IPR002376" /db_xref="InterPro:IPR004607" /db_xref="InterPro:IPR036477" /db_xref="SubtiList:BG10709" /db_xref="UniProtKB/Swiss-Prot:P12040" /translation="MKKFAVFASGNGSNFEAIVTRLKEENWDASAALLVCDKPQAKVI ERAEAFHIPSFAFEPKSYENKAAFEQAIIEQLRLHEVELIALAGYMRLIGDTLLQAYG GKIINIHPSLLPAFPGIDAVGQAFRAGVKVAGITVHYVDEGMDTGPIIAQKAIEIDEH DTLETIEQRIHKLEHKWYPSVIKQLLGLNNRGEKA*" gene 708010..708597 /gene="purN" /locus_tag="BSU_06510" /old_locus_tag="BSU06510" misc_feature 708020..708034 /Source="Nicolas_upshift_promotors" /id="U500" /multdbtbs="-" /comp="M18" /sig="SigL" /pcomp="0.52947052947053" /psig="0.52947052947053" /xcortree=2706 /SigmaFactorBS="aaaaaaggtgaaggcgtcacattcggcggtgcggcactttca tgaaaaagtTTGCGGTATTTGCATcaggaaacggttcaaacttcgaagccatcgtcac g" /listShort="purN, purH, purD" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 708029 /Source="Nicolas_upshifts" /id="U500" /multdbtbs="-" /comp="M18" /sig="SigL" /pcomp="0.52947052947053" /psig="0.52947052947053" /xcortree=2706 /SigmaFactorBS="aaaaaaggtgaaggcgtcacattcggcggtgcggcactttca tgaaaaagtTTGCGGTATTTGCATcaggaaacggttcaaacttcgaagccatcgtcac g" /listShort="purN, purH, purD" /GFF_Attribute="listLong" promotor_-10 complement(708296..708314) /Source="Nicolas_upshift_promotors" /id="U501" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=1204 /SigmaFactorBS="tccaggaaacgccggaagaagcgatgggTGAATGttaatgat ttttcccCCATATGCTTGAAGGAGCGtatcaccgatcagcctcatatagccggcaaga g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(708303) /Source="Nicolas_upshifts" /id="U501" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=1204 /SigmaFactorBS="tccaggaaacgccggaagaagcgatgggTGAATGttaatgat ttttcccCCATATGCTTGAAGGAGCGtatcaccgatcagcctcatatagccggcaaga g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(708330..708335) /Source="Nicolas_upshift_promotors" /id="U501" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=1204 /SigmaFactorBS="tccaggaaacgccggaagaagcgatgggTGAATGttaatgat ttttcccCCATATGCTTGAAGGAGCGtatcaccgatcagcctcatatagccggcaaga g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" CDS 708594..710132 /gene="purH" /locus_tag="BSU_06520" /old_locus_tag="BSU06520" /EC_number="2.1.2.3" /EC_number="3.5.4.10" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 12787499, 1937050, 9683488; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="fused phosphoribosylaminoimidazole carboxy formyl formyltransferase; inosine-monophosphate cyclohydrolase" /protein_id="NP_388534.2" /db_xref="EnsemblGenomes-Gn:BSU06520" /db_xref="EnsemblGenomes-Tr:CAB12472" /db_xref="GOA:P12048" /db_xref="InterPro:IPR002695" /db_xref="InterPro:IPR011607" /db_xref="InterPro:IPR016193" /db_xref="InterPro:IPR024051" /db_xref="InterPro:IPR036914" /db_xref="SubtiList:BG10710" /db_xref="UniProtKB/Swiss-Prot:P12048" /translation="MTIKRALISVSDKTNLVPFVKELTELGVEVISTGGTKKLLQENG VDVIGISEVTGFPEIMDGRLKTLHPNIHGGLLAVRGNEEHMAQINEHGIQPIDLVVVN LYPFKETISKEDVTYEEAIENIDIGGPGMLRAASKNHQDVTVIVDPADYSPVLNQIKE EGSVSLQKKRELAAKVFRHTAAYDALIADYLTNVVGEKEPEQFTVTFEKKQSLRYGEN PHQEATFYQTALPVKGSIAQAEQLHGKELSYNNIKDADAAVQIVREFTEPAAVAVKHM NPCGVGTGKTIAEAFDRAFEADKTSIFGGIIALNREVDKATAEALHNIFLEIIIAPSF SQEALDVLTAKKNLRLLTLDVSAAVQKEKQLTSVQGGLLIQDLDMHGFDDAEISIPTK REPNEQEWEDLKLAWKVVKHVKSNAIVLAKDNMTVGVGAGQMNRVGSAKIAIEQAGEK AKGSALGSDAYFPMPDTVEEAAKAGVTAIIQPGGSIRDEDSIKKADEYGIAMVFTGIR HFKH*" gene 708594..710132 /gene="purH" /locus_tag="BSU_06520" /old_locus_tag="BSU06520" CDS 710148..711416 /gene="purD" /locus_tag="BSU_06530" /old_locus_tag="BSU06530" /EC_number="6.3.4.13" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:9683488, 12787499, 16321950" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9683488, 12787499, 16321950; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="phosphoribosylglycinamide synthetase" /protein_id="NP_388535.1" /db_xref="EnsemblGenomes-Gn:BSU06530" /db_xref="EnsemblGenomes-Tr:CAB12473" /db_xref="GOA:P12039" /db_xref="InterPro:IPR000115" /db_xref="InterPro:IPR011054" /db_xref="InterPro:IPR011761" /db_xref="InterPro:IPR013815" /db_xref="InterPro:IPR016185" /db_xref="InterPro:IPR020559" /db_xref="InterPro:IPR020560" /db_xref="InterPro:IPR020561" /db_xref="InterPro:IPR020562" /db_xref="InterPro:IPR037123" /db_xref="PDB:2XCL" /db_xref="PDB:2XD4" /db_xref="SubtiList:BG10711" /db_xref="UniProtKB/Swiss-Prot:P12039" /translation="MNVLIIGKGGREHTLAWKAAQSSLVENVFAAPGNDGMAASAQLV NIEESDHAGLVSFAKQNQVGLTIVGPEVPLIEGLVDEFEKAGLHVFGPSKAAAIIEGS KQFAKDLMKKYDIPTAEYETFTSFDEAKAYVQEKGAPIVIKADGLAAGKGVTVAMTEE EAIACLHDFLEDEKFGDASASVVIEEYLSGEEFSLMAFVKGEKVYPMVIAQDHKRAFD GDKGPNTGGMGAYSPVPQISEETVRHAVETIVKPAAKAMVQEGRSFTGVLYAGLMLTE NGSKVIEFNARFGDPETQVVLPRMESDLVQVLLDLLDDKEVDLRWKDTAAVSVVLASE GYPESYAKGTPIGSLAAETEQVVVFHAGTKAEGGEFVTNGGRVANVTAFDETFEAARD RVYKAVDEIFKPGLFFRKDIGARALKAAQK*" gene 710148..711416 /gene="purD" /locus_tag="BSU_06530" /old_locus_tag="BSU06530" downshifts 711401 /Source="Nicolas_upshifts" /id="D320" /incds=0 /nref=140 /ntot=249 /MaxReadThrough="2.77191" /MaxDrop="5.90939" /score="30.0999687" /energy="-11.4" /TU="NA" /idTUdmin="U500" /TUdmin=6 /isTUend="TRUE" CDS complement(711456..711875) /gene="yezC" /locus_tag="BSU_06540" /old_locus_tag="BSU06540" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative transcriptional regulator (Lrp/AsnC family)" /protein_id="NP_388536.2" /db_xref="EnsemblGenomes-Gn:BSU06540" /db_xref="EnsemblGenomes-Tr:CAB12474" /db_xref="GOA:O31497" /db_xref="InterPro:IPR000485" /db_xref="InterPro:IPR011008" /db_xref="InterPro:IPR011991" /db_xref="InterPro:IPR019885" /db_xref="InterPro:IPR019887" /db_xref="InterPro:IPR019888" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG12874" /db_xref="UniProtKB/Swiss-Prot:O31497" /translation="MDDTDLQILSHLQRNGRLTMVELGKLVGLSSPSAAERVRKLEDK GVITGYSANICYEKLNKHVTAFILMEPKSCKHYAAFATSHPDVAENHRITGMYSYVTK VVTESVHTLEDFIDTSMAHGKPTTLVVLSSSSCHPAF*" gene complement(711456..711875) /gene="yezC" /locus_tag="BSU_06540" /old_locus_tag="BSU06540" misc_feature complement(711945..711964) /Source="Nicolas_upshift_promotors" /id="U502" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.99000999000999" /psig="0.999000999001" /xcortree=3125 /SigmaFactorBS="ccccctctctgattgatggctttattatagaaaaaataagac ggcatccaTATGCTACAATGAAGTTAAAtcaacagcattaccttacgatcaaaggaat t" /listShort="yezC" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(711954) /Source="Nicolas_upshifts" /id="U502" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.99000999000999" /psig="0.999000999001" /xcortree=3125 /SigmaFactorBS="ccccctctctgattgatggctttattatagaaaaaataagac ggcatccaTATGCTACAATGAAGTTAAAtcaacagcattaccttacgatcaaaggaat t" /listShort="yezC" /GFF_Attribute="listLong" CDS 712019..713293 /gene="yecA" /locus_tag="BSU_06550" /old_locus_tag="BSU06550" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406, 26319875, 27723097, 24678831; Product type t : transporter" /codon_start=1 /transl_table=11 /product="putative amino acid exporter" /protein_id="NP_388537.2" /db_xref="EnsemblGenomes-Gn:BSU06550" /db_xref="EnsemblGenomes-Tr:CAB12475" /db_xref="GOA:O34560" /db_xref="InterPro:IPR002293" /db_xref="SubtiList:BG12817" /db_xref="UniProtKB/Swiss-Prot:O34560" /translation="MLPELQRSITWIQGTALTIGAVLGCGILILPSVTADTAGPASLF VWVFMSFLSFFLVGTLARLVKIAPSAGGITAYVQLAFQKKAGAILGWIMLGSVPIGVP IIALTGAHYVSYITEAADWQITLIAGCMLAISILLHMRGIQLSANISTLVICVIVFLL VTSIAVSLPHVTIAEFKPFLPHGWSAAGSVSVMIFFSFVGWEMITPLAEEFHRPEKDV PLSLFLAASCVAGLYIMLSFVTVGTHSYGENGEIASLAMLISKGAGESGVYVTVCLAL FITFATIHANIAGFSRMVYALAREGHIPVFFGKLSATKRTPIRVLTAMAAVFGLVLAA HGLFQIDLTTLLKGPSAAFIASYICTMAAALKLLGRRDIGWWMALGAFVACAVIYSFS GWALLYPAVLAAAGYFYMKTKGGHKKKLDHVL*" gene 712019..713293 /gene="yecA" /locus_tag="BSU_06550" /old_locus_tag="BSU06550" downshifts 713242 /Source="Nicolas_upshifts" /id="D321" /incds=0 /nref=4 /ntot=64 /MaxReadThrough="0.796809999999999" /MaxDrop="2.92696" /score="1.68718502" /energy="-14.2" /TU="NA" /idTUdmin="U498" /TUdmin=1825 /isTUend="FALSE" CDS complement(713308..713535) /gene="yezF" /locus_tag="BSU_06559" /old_locus_tag="BSU06559" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_003097691.1" /db_xref="EnsemblGenomes-Gn:BSU06559" /db_xref="EnsemblGenomes-Tr:CAX52578" /db_xref="GOA:C0H3X3" /db_xref="InterPro:IPR021309" /db_xref="UniProtKB/Swiss-Prot:C0H3X3" /translation="MKPNISLINAVFRIACGLTIMSAASAKFTKKPWCRMHLFYIFMG AMKAGSGILRFCPVTYMFQHSDSGNNEHQNG*" gene complement(713308..713535) /gene="yezF" /locus_tag="BSU_06559" /old_locus_tag="BSU06559" downshifts complement(713319) /Source="Nicolas_upshifts" /id="D322" /incds=0 /nref=29 /ntot=46 /MaxReadThrough="0.14199" /MaxDrop="6.82335" /score="34.1397958" /energy="-13.9" /TU="NA" /idTUdmin="U504" /TUdmin=0 /isTUend="TRUE" S_feature complement(713536..713956) /Source="Nicolas_S_feature" /locus_tag="new_713536_713956_c" /HighExp="S8, S7, S5, S6, S4, ferm, nit, BT, Pyr, T5.0H" /AntisenseName="yerA" /AntisenseCor="0.38264258041500998" /AntisenseRegPval="-10.1" /CDS_PredictionProba="NA" /TUshortSig="SigGF" /TUshortPSig="0.996" /TUlongSig="NA" /TUlongPSig="NA" /label="S233" promotor_-35 713603..713608 /Source="Nicolas_upshift_promotors" /id="U503" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.59040959040959" /psig=1 /xcortree=1592 /SigmaFactorBS="aaaagttttttaatcgaaccttcaaaaatttgtaacgttttt atCGTGCGtgatgaggaaggaTGTGATACCATGAGTCTAATacatgtaaaggagagta t" /listShort="yerA, yerB, yerC" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 713619 /Source="Nicolas_upshifts" /id="U503" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.59040959040959" /psig=1 /xcortree=1592 /SigmaFactorBS="aaaagttttttaatcgaaccttcaaaaatttgtaacgttttt atCGTGCGtgatgaggaaggaTGTGATACCATGAGTCTAATacatgtaaaggagagta t" /listShort="yerA, yerB, yerC" /GFF_Attribute="listLong" promotor_-10 713622..713641 /Source="Nicolas_upshift_promotors" /id="U503" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.59040959040959" /psig=1 /xcortree=1592 /SigmaFactorBS="aaaagttttttaatcgaaccttcaaaaatttgtaacgttttt atCGTGCGtgatgaggaaggaTGTGATACCATGAGTCTAATacatgtaaaggagagta t" /listShort="yerA, yerB, yerC" /GFF_Attribute="listLong" /label="promotor_-10" CDS 713664..715406 /gene="yerA" /locus_tag="BSU_06560" /old_locus_tag="BSU06560" /EC_number="3.5.4.2" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 23109554; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative adenine deaminase YerA" /protein_id="NP_388538.1" /db_xref="EnsemblGenomes-Gn:BSU06560" /db_xref="EnsemblGenomes-Tr:CAB12476" /db_xref="GOA:O34909" /db_xref="InterPro:IPR006679" /db_xref="InterPro:IPR006680" /db_xref="InterPro:IPR011059" /db_xref="InterPro:IPR026912" /db_xref="InterPro:IPR032466" /db_xref="SubtiList:BG12829" /db_xref="UniProtKB/Swiss-Prot:O34909" /translation="MSERTFNWKNKDIRAQVDVVDSKLLPTLLLRNALVLNPYVKQWL KKNIWIYQDRIVYVGHELPNRAEEIHTIDCEGKYIVPGYIEPHAHPFQIYNPQTLAEY VSQYGTTTFVNDNLFLLLQSGKKKALTILNELKKQPVQYFWWSRYDLQTEVLNEDHVL PFDVRKQWIEHPDVIQGGEMTGWPRLVDGDDLMLHCMQATKKQRKRIEGHFPGASDKT LTKMKLFGADCDHEAMTGDEVMRRLELGYYVSLRNSSIRPDVRKILQELHEKGFRYYD HFFYTTDGATPNFYKGGMTNELIRIALEEGVPAIDAYNMASFNIAKYYQMDDYLGVVG PGRLASLNILEDPLNPNPVTVLSKGTILRENGCDLKAFTKTDWHKGGLVPLELSYDMT MDDLQFSMPMGVKMRNAVIMEPYMIEIDNSMEQLSFDHDESYLTMLDRHGKWRVNTMI KGFASSVQGFVSSFTTTGDIVAIGKNKADMLLAFARMKEIGGGIVLAENGNILHEIPL ALCGCASSEAYEDVLEKEQKLRDLLTERGYEFCDPIYTLLFLQSTHLPYIRITPRGIF DVMKKTVLFPSIMR*" gene 713664..715406 /gene="yerA" /locus_tag="BSU_06560" /old_locus_tag="BSU06560" promotor_-10 complement(713941..713952) /Source="Nicolas_upshift_promotors" /id="U504" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.996003996003996" /psig="0.996003996003996" /xcortree=923 /SigmaFactorBS="aaaaataagttatcattcacgaatgtcgttgttccgtattga gaCACATATtccgccagtgtttGGGGATTATATAtttgaaaaggatgtgcgtgcggtt c" /listShort="S233, yezF" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(713956) /Source="Nicolas_upshifts" /id="U504" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.996003996003996" /psig="0.996003996003996" /xcortree=923 /SigmaFactorBS="aaaaataagttatcattcacgaatgtcgttgttccgtattga gaCACATATtccgccagtgtttGGGGATTATATAtttgaaaaggatgtgcgtgcggtt c" /listShort="S233, yezF" /GFF_Attribute="listLong" promotor_-35 complement(713966..713972) /Source="Nicolas_upshift_promotors" /id="U504" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.996003996003996" /psig="0.996003996003996" /xcortree=923 /SigmaFactorBS="aaaaataagttatcattcacgaatgtcgttgttccgtattga gaCACATATtccgccagtgtttGGGGATTATATAtttgaaaaggatgtgcgtgcggtt c" /listShort="S233, yezF" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 713987 /Source="Nicolas_upshifts" /id="D323" /incds=1 /nref=13 /ntot=109 /MaxReadThrough="7.92321" /MaxDrop="3.44855" /score="1.68718502" /energy="-14.2" /TU="U503" /idTUdmin="U498" /TUdmin=2570 /isTUend="FALSE" promotor_-35 715380..715386 /Source="Nicolas_upshift_promotors" /id="U505" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.4995004995005" /psig="0.996003996003996" /xcortree=2171 /SigmaFactorBS="cgcattacgccaagaggaatattcgacgtcatgaaaaaaact GTACTCTttccatcgataaTGCGTTAAAATATAAAAGAGcagggagccgacatatgaa a" /listShort="yerB, yerC" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 715398 /Source="Nicolas_upshifts" /id="U505" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.4995004995005" /psig="0.996003996003996" /xcortree=2171 /SigmaFactorBS="cgcattacgccaagaggaatattcgacgtcatgaaaaaaact GTACTCTttccatcgataaTGCGTTAAAATATAAAAGAGcagggagccgacatatgaa a" /listShort="yerB, yerC" /GFF_Attribute="listLong" promotor_-10 715399..715418 /Source="Nicolas_upshift_promotors" /id="U505" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.4995004995005" /psig="0.996003996003996" /xcortree=2171 /SigmaFactorBS="cgcattacgccaagaggaatattcgacgtcatgaaaaaaact GTACTCTttccatcgataaTGCGTTAAAATATAAAAGAGcagggagccgacatatgaa a" /listShort="yerB, yerC" /GFF_Attribute="listLong" /label="promotor_-10" CDS 715433..716428 /gene="yerB" /locus_tag="BSU_06570" /old_locus_tag="BSU06570" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 12073041; Product type lp: lipoprotein" /codon_start=1 /transl_table=11 /product="putative lipoprotein" /protein_id="NP_388539.1" /db_xref="EnsemblGenomes-Gn:BSU06570" /db_xref="EnsemblGenomes-Tr:CAB12477" /db_xref="GOA:O34968" /db_xref="InterPro:IPR021416" /db_xref="InterPro:IPR023158" /db_xref="InterPro:IPR035328" /db_xref="PDB:2PSB" /db_xref="SubtiList:BG12830" /db_xref="UniProtKB/Swiss-Prot:O34968" /translation="MKKWMTVCALCFVFFLLVSCQQKDAVPDTAKKLKAPLTGLKTEQ KVTERRPVAVVVNNHPKARPQSGLSKADIVIEALAEGQITRFLAIFQSQMPETVGPVR SAREYFVTLSNGFDSIFVHHGWSPGAKKQLESGAADYMNGLDFDGSLFWRADFSKPPH NSYTSYDYIKKAAEQKGYKLKQETNPLLFQTSDAKPANESYNVRVDYGTNNVTNLVEY NYDKKAEFYTRSSDGVITTDRETGKPVAMQNIFIVEASHHIIDQDGRRDIDLESGGKG LLFQHGNVIETDWKQVNGRIVPVKDGKWLPFVPGKTWINIVPDLDAASISKGEGV*" gene 715433..716428 /gene="yerB" /locus_tag="BSU_06570" /old_locus_tag="BSU06570" CDS 716431..716745 /gene="yerC" /locus_tag="BSU_06580" /old_locus_tag="BSU06580" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2b: Function from indirect experimental evidences (e.g. phenotypes); PubMedId: 23504016, 26735940; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional repressor-histidine operons" /protein_id="NP_388540.1" /db_xref="EnsemblGenomes-Gn:BSU06580" /db_xref="EnsemblGenomes-Tr:CAB12478" /db_xref="GOA:Q7BVT7" /db_xref="InterPro:IPR000831" /db_xref="InterPro:IPR010921" /db_xref="InterPro:IPR013368" /db_xref="SubtiList:BG12831" /db_xref="UniProtKB/Swiss-Prot:Q7BVT7" /translation="MQIDKLRGKELDQLFNSILSLKDLEECYRFFDDLCTINEIQSLA QRLEVARMLREGNTYHKIETETGASTATISRVKRCLNYGNDAYEMALDRVKETETESS SK*" gene 716431..716745 /gene="yerC" /locus_tag="BSU_06580" /old_locus_tag="BSU06580" downshifts 716608 /Source="Nicolas_upshifts" /id="D324" /incds=1 /nref=1 /ntot=25 /MaxReadThrough="7.1005" /MaxDrop="2.3494" /score="10.9674476" /energy="-15.8" /TU="U503,U505" /idTUdmin="U503" /TUdmin="-374" /isTUend="FALSE" downshifts 716750 /Source="Nicolas_upshifts" /id="D325" /incds=0 /nref=78 /ntot=262 /MaxReadThrough="3.58776" /MaxDrop="5.59364" /score="10.9674476" /energy="-15.8" /TU="U503,U505" /idTUdmin="U503" /TUdmin="-232" /isTUend="FALSE" CDS complement(716780..718357) /gene="yerD" /locus_tag="BSU_06590" /old_locus_tag="BSU06590" /EC_number="1.4.1.13" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15805528, 17114254, 19948795; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative osmotic shock glutamate synthase subunit (flavoprotein subunit, ferredoxin-dependent)" /protein_id="NP_388541.1" /db_xref="EnsemblGenomes-Gn:BSU06590" /db_xref="EnsemblGenomes-Tr:CAB12479" /db_xref="GOA:O34849" /db_xref="InterPro:IPR002932" /db_xref="InterPro:IPR013785" /db_xref="InterPro:IPR024188" /db_xref="InterPro:IPR027283" /db_xref="SubtiList:BG12832" /db_xref="UniProtKB/Swiss-Prot:O34849" /translation="METIIIALIAFIIGIIAIPIVLFAWIYIKDEKQQEHSILRNYPV IGRFRYILEKIGPELRQYLYSNDNEEQPFSRKEYEQTVISGKYKSRMMGFGSVRDFDK PGYYIRNAMFPKQREEMHVNQTPKIETQIYKMDADNLFKRKEHAEHIKADPYFLHPDD VQVIGEHTCEKPFYVKGLVGQSAMSYGSLGERAVTALSKGLHLAGGTWMNTGEGGLSE YHLKGGADIICQIGPGLFGVRKRNGEFSWEEFKRKSRIDQIKAFELKLAQGAKTRGGH VDGAKVSEEVADIRNVEPGKSIDSPNRFYEFSNPPEMLDFIEKLRDVGQKPVGIKLVA GHPEELHELFSHMQKSGKHPDFITIDGSEGGTGASFYELADTVGLPIMTALPIVDTLL KQYGLRSQLKIFASGKLLTPDKIAVALALGADFVNIARGMMFSVGCIRALVCHTNTCP AGVATTDPKLQKALSVEEKQHRVCNYVISLREGLFNLAAAAGINSPIHFSKEHVVYRK EDGSIINIDNLIHQFVS*" gene complement(716780..718357) /gene="yerD" /locus_tag="BSU_06590" /old_locus_tag="BSU06590" downshifts complement(716794) /Source="Nicolas_upshifts" /id="D326" /incds=0 /nref=7 /ntot=24 /MaxReadThrough="2.99325" /MaxDrop="5.6389" /score="34.8793815" /energy="-15.8" /TU="U506" /idTUdmin="U506" /TUdmin="-88" /isTUend="FALSE" promotor_-10 complement(718371..718390) /Source="Nicolas_upshift_promotors" /id="U506" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=244 /SigmaFactorBS="ggcaggagcacacatttttcaccagattccttctgctatTGT TTGGaaagtgttctactgTGGAAATGGTTACATAAAAAgggaggctgagagatggaaa c" /listShort="yerD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(718390) /Source="Nicolas_upshifts" /id="U506" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=244 /SigmaFactorBS="ggcaggagcacacatttttcaccagattccttctgctatTGT TTGGaaagtgttctactgTGGAAATGGTTACATAAAAAgggaggctgagagatggaaa c" /listShort="yerD" /GFF_Attribute="listLong" promotor_-35 complement(718405..718411) /Source="Nicolas_upshift_promotors" /id="U506" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=244 /SigmaFactorBS="ggcaggagcacacatttttcaccagattccttctgctatTGT TTGGaaagtgttctactgTGGAAATGGTTACATAAAAAgggaggctgagagatggaaa c" /listShort="yerD" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 718554..718557 /Source="Nicolas_upshift_promotors" /id="U507" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.95004995004995" /psig=1 /xcortree=2610 /SigmaFactorBS="aaaacacctttttcagtgaataacgagattaacggctttttc cGTTTttccgcgctatgtgaaTTTGTTATAATGTTTAAATGgtaacaaacgaatggag g" /listShort="pcrB, pcrA, ligA, yerH, S234, yerI" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 718571 /Source="Nicolas_upshifts" /id="U507" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.95004995004995" /psig=1 /xcortree=2610 /SigmaFactorBS="aaaacacctttttcagtgaataacgagattaacggctttttc cGTTTttccgcgctatgtgaaTTTGTTATAATGTTTAAATGgtaacaaacgaatggag g" /listShort="pcrB, pcrA, ligA, yerH, S234, yerI" /GFF_Attribute="listLong" promotor_-10 718574..718593 /Source="Nicolas_upshift_promotors" /id="U507" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.95004995004995" /psig=1 /xcortree=2610 /SigmaFactorBS="aaaacacctttttcagtgaataacgagattaacggctttttc cGTTTttccgcgctatgtgaaTTTGTTATAATGTTTAAATGgtaacaaacgaatggag g" /listShort="pcrB, pcrA, ligA, yerH, S234, yerI" /GFF_Attribute="listLong" /label="promotor_-10" CDS 718622..719308 /gene="pcrB" /locus_tag="BSU_06600" /old_locus_tag="BSU06600" /function="16.13: Shape" /function="16.2: Construct biomass (Anabolism)" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:16377641, 21761520, 21214173, 27226549" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16377641, 21761520, 21214173, 27226549; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="heptaprenylglyceryl-phosphate synthase" /protein_id="NP_388542.1" /db_xref="EnsemblGenomes-Gn:BSU06600" /db_xref="EnsemblGenomes-Tr:CAB12480" /db_xref="GOA:O34790" /db_xref="InterPro:IPR008205" /db_xref="PDB:1VIZ" /db_xref="PDB:3VZX" /db_xref="PDB:3VZY" /db_xref="PDB:3VZZ" /db_xref="PDB:3W00" /db_xref="SubtiList:BG12833" /db_xref="UniProtKB/Swiss-Prot:O34790" /translation="MYDVTEWKHVFKLDPNKDLPDEQLEILCESGTDAVIIGGSDGVT EDNVLRMMSKVRRFLVPCVLEVSAIEAIVPGFDLYFIPSVLNSKNADWIVGMHQKAMK EYGELMSMEEIVAEGYCIANPDCKAAALTEADADLNMDDIVAYARVSELLQLPIFYLE YSGVLGDIEAVKKTKAVLETSTLFYGGGIKDAETAKQYAEHADVIVVGNAVYEDFDRA LKTVAAVKGE*" gene 718622..719308 /gene="pcrB" /locus_tag="BSU_06600" /old_locus_tag="BSU06600" CDS 719370..721589 /gene="pcrA" /locus_tag="BSU_06610" /old_locus_tag="BSU06610" /EC_number="3.6.4.12" /function="16.6: Maintain" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 12073041, 12682299, 14594837, 16267290, 26070154; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="ATP-dependent DNA helicase" /protein_id="NP_388543.1" /db_xref="EnsemblGenomes-Gn:BSU06610" /db_xref="EnsemblGenomes-Tr:CAB12481" /db_xref="GOA:O34580" /db_xref="InterPro:IPR000212" /db_xref="InterPro:IPR005751" /db_xref="InterPro:IPR014016" /db_xref="InterPro:IPR014017" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR034739" /db_xref="SubtiList:BG12834" /db_xref="UniProtKB/Swiss-Prot:O34580" /translation="MNYISNQLLSGLNPVQQEAVKTTDGPLLLMAGAGSGKTRVLTHR IAYLMAEKHVAPWNILAITFTNKAAREMKERVESILGPGADDIWISTFHSMCVRILRR DIDRIGINRNFSILDTADQLSVIKGILKERNLDPKKFDPRSILGTISSAKNELTEPEE FSKVAGGYYDQVVSDVYADYQKKLLKNQSLDFDDLIMTTIKLFDRVPEVLEFYQRKFQ YIHVDEYQDTNRAQYMLVKQLAERFQNLCVVGDSDQSIYRWRGADITNILSFEKDYPN ASVILLEQNYRSTKRILRAANEVIKNNSNRKPKNLWTENDEGIKISYYRGDNEFGEGQ FVAGKIHQLHSTGKRKLSDIAILYRTNAQSRVIEETLLKAGLNYNIVGGTKFYDRKEI KDILAYLRLVSNPDDDISFTRIVNVPKRGVGATSLEKIASYAAINGLSFFQAIQQVDF IGVSAKAANALDSFRQMIENLTNMQDYLSITELTEEILDKTEYREMLKAEKSIEAQSR LENIDEFLSVTKNFEQKSEDKTLVAFLTDLALIADIDQLDQKEEESGGKDAITLMTLH AAKGLEFPVVFLMGLEEGVFPHSRSLMEEAEMEEERRLAYVGITRAEQELYLTNAKMR TLFGRTNMNPESRFIAEIPDDLLENLNEKKETRATSARKMQPRRGPVSRPVSYASKTG GDTLNWAVGDKAGHKKWGTGTVVSVKGEGEGTELDIAFPSPVGVKRLLAAFAPIEKQ* " gene 719370..721589 /gene="pcrA" /locus_tag="BSU_06610" /old_locus_tag="BSU06610" CDS 721613..723619 /gene="ligA" /locus_tag="BSU_06620" /old_locus_tag="BSU06620" /EC_number="6.5.1.2" /function="16.6: Maintain" /function="16.9: Replicate" /experiment="publication(s) with functional evidences, PMID:164915, 11095673, 12682299, 16267290" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 164915, 11095673, 12682299, 16267290; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="DNA ligase (NAD-dependent)" /protein_id="NP_388544.1" /db_xref="EnsemblGenomes-Gn:BSU06620" /db_xref="EnsemblGenomes-Tr:CAB12482" /db_xref="GOA:O31498" /db_xref="InterPro:IPR001357" /db_xref="InterPro:IPR001679" /db_xref="InterPro:IPR003583" /db_xref="InterPro:IPR004149" /db_xref="InterPro:IPR004150" /db_xref="InterPro:IPR010994" /db_xref="InterPro:IPR012340" /db_xref="InterPro:IPR013839" /db_xref="InterPro:IPR013840" /db_xref="InterPro:IPR018239" /db_xref="InterPro:IPR033136" /db_xref="InterPro:IPR036420" /db_xref="SubtiList:BG12835" /db_xref="UniProtKB/Swiss-Prot:O31498" /translation="MDKETAKQRAEELRRTINKYSYEYYTLDEPSVPDAEYDRLMQEL IAIEEEHPDLRTPDSPTQRVGGAVLEAFQKVTHGTPMLSLGNAFNADDLRDFDRRVRQ SVGDDVAYNVELKIDGLAVSLRYEDGYFVRGATRGDGTTGEDITENLKTIRNIPLKMN RELSIEVRGEAYMPKRSFEALNEERIKNEEEPFANPRNAAAGSLRQLDPKIAAKRNLD IFVYSIAELDEMGVETQSQGLDFLDELGFKTNQERKKCGSIEEVITLIDELQAKRADL PYEIDGIVIKVDSLDQQEELGFTAKSPRWAIAYKFPAEEVVTKLLDIELNVGRTGVIT PTAILEPVKVAGTTVSRASLHNEDLIKEKDIRILDKVVVKKAGDIIPEVVNVLVDQRT GEEKEFSMPTECPECGSELVRIEGEVALRCINPECPAQIREGLIHFVSRNAMNIDGLG ERVITQLFEENLVRNVADLYKLTKERVIQLERMGEKSTENLISSIQKSKENSLERLLF GLGIRFIGSKAAKTLAMHFESLENLKKASKEELLAVDEIGEKMADAVITYFHKEEMLE LLNELQELGVNTLYKGPKKVKAEDSDSYFAGKTIVLTGKLEELSRNEAKAQIEALGGK LTGSVSKNTDLVIAGEAAGSKLTKAQELNIEVWNEEQLMGELKK*" gene 721613..723619 /gene="ligA" /locus_tag="BSU_06620" /old_locus_tag="BSU06620" CDS 723635..724825 /gene="yerH" /locus_tag="BSU_06630" /old_locus_tag="BSU06630" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 16267290; Product type lp: lipoprotein" /codon_start=1 /transl_table=11 /product="putative lipoprotein" /protein_id="NP_388545.1" /db_xref="EnsemblGenomes-Gn:BSU06630" /db_xref="EnsemblGenomes-Tr:CAB12483" /db_xref="GOA:O34629" /db_xref="InterPro:IPR011426" /db_xref="SubtiList:BG12836" /db_xref="UniProtKB/Swiss-Prot:O34629" /translation="MKKTLALAATAAVLMLSACSSGFGGEKEEEITQKTAKSSEKAIV PKYNISDSYYKMVLPFKAGKARGLTTEQLNTRLDIDEFETGLMRLAQDSFSTDDYLFQ EGQYLDEDTVLSWLARKKTGSDLKKAEKEDKNFKNEGLNPALPSSGSTEEKNESSPIY LASMLEHDYLVRKDKNSIQLGGVMIGLALNSVYYYREKTGDPQKEVEIKDSTLRQQGE KIAQEVINRLRKKDNLKNVPITVALYKQASKTSIVPGNFIAKTEVKAGSTDISNWDDI NEKYVFYPADTTTAEKYPDDTEVFKRFKNSIEEYFPNYTGVVGTALYENDEMKKMKID IPMQFYGKSEVVAFTQFLTGEVMDYYSKSSVDVEVNITSSDGQEAVIIRNAGDKEPTV HIYD*" gene 723635..724825 /gene="yerH" /locus_tag="BSU_06630" /old_locus_tag="BSU06630" misc_feature complement(723830..723834) /Source="Nicolas_upshift_promotors" /id="U508" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.986013986013986" /psig="0.000999000999001" /xcortree=36 /SigmaFactorBS="atcagccctgtttcaaattcgtcaatgtccagccttgtattc agctgttccgttgttaagCCGCGcgctttgcctgccttaaacggcagcaccattttgt a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(723834) /Source="Nicolas_upshifts" /id="U508" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.986013986013986" /psig="0.000999000999001" /xcortree=36 /SigmaFactorBS="atcagccctgtttcaaattcgtcaatgtccagccttgtattc agctgttccgttgttaagCCGCGcgctttgcctgccttaaacggcagcaccattttgt a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" misc_feature 724862..724881 /Source="Nicolas_upshift_promotors" /id="U509" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.971028971028971" /psig=1 /xcortree=3168 /SigmaFactorBS="tcacatttatgactgatagaaaacccttgtgccatattggca caagggttttTATGTTACAATTAACAGGAAaagggaaaatattttcacttctgccgaa a" /listShort="S234, yerI" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" S_feature 724870..724986 /Source="Nicolas_S_feature" /locus_tag="new_724870_724986" /HighExp="LoTm, B60, Lbstat, B36, BI, M9-stat, T1.30H, ferm, T3.30H, M40t90" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="1, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S234" upshifts 724870 /Source="Nicolas_upshifts" /id="U509" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.971028971028971" /psig=1 /xcortree=3168 /SigmaFactorBS="tcacatttatgactgatagaaaacccttgtgccatattggca caagggttttTATGTTACAATTAACAGGAAaagggaaaatattttcacttctgccgaa a" /listShort="S234, yerI" /GFF_Attribute="listLong" downshifts complement(724934) /Source="Nicolas_upshifts" /id="D327" /incds=0 /nref=2 /ntot=118 /MaxReadThrough="1.21197" /MaxDrop="3.77048" /score="18.5253059" /energy="-17.7" /TU="NA" /idTUdmin="U511" /TUdmin=1122 /isTUend="FALSE" CDS 724987..725997 /gene="yerI" /locus_tag="BSU_06640" /old_locus_tag="BSU06640" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative kinase" /protein_id="NP_388546.1" /db_xref="EnsemblGenomes-Gn:BSU06640" /db_xref="EnsemblGenomes-Tr:CAB12484" /db_xref="InterPro:IPR002575" /db_xref="InterPro:IPR011009" /db_xref="SubtiList:BG12837" /db_xref="UniProtKB/Swiss-Prot:O34640" /translation="MLDVHKDIKKIFHEEQVLAEAAARYGFSKDQVRFLADAENYVYE CMKDNQPYILKITHTIRRSSDYMMGEMEWLRHLAIGGISVAKPLPSLNGKDVEAVPDG NGGSFLLRVYEKAPGQKVDESDWNETLFYELGRYTGSMHSLTKSYKLSNPAFKRQEWD EEEQLKLRKYVPEDQIKVFQQADSLMNELRRLPKSQDNYGLVHADLHHGNFNWDHGKI TAFDFDDIGYNWFVNDISILLYNVLWYPVVPYDDKAAFTEEFMTHFMKGYWEENELDP AWLMIIPDFLRLRHMLIYGLLHQMFDLNTIGEEEKEMLAGFRRDIENGTPITAFDFSA LV*" gene 724987..725997 /gene="yerI" /locus_tag="BSU_06640" /old_locus_tag="BSU06640" promotor_no_box complement(725004..725104) /Source="Nicolas_upshift_promotors" /id="U510" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.993006993006993" /psig=0 /xcortree=53 /SigmaFactorBS="tttccgcatcagccagaaaacgcacctgatcttttgagaaac cgtatctcgctgcagcttctgccaaaacctgctcttcatgaaatatttttttgatatc t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_no_box" upshifts complement(725044) /Source="Nicolas_upshifts" /id="U510" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.993006993006993" /psig=0 /xcortree=53 /SigmaFactorBS="tttccgcatcagccagaaaacgcacctgatcttttgagaaac cgtatctcgctgcagcttctgccaaaacctgctcttcatgaaatatttttttgatatc t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" downshifts 725980 /Source="Nicolas_upshifts" /id="D328" /incds=0 /nref=137 /ntot=253 /MaxReadThrough="3.07041" /MaxDrop="5.10987" /score="12.7441524" /energy="-17" /TU="NA" /idTUdmin="U507" /TUdmin=0 /isTUend="TRUE" S_feature 726024..726828 /Source="Nicolas_S_feature" /locus_tag="new_726024_726828" /HighExp="B60, B36, LoTm, M9-stat, Cold, T1.30H, T0.30H, ferm, Lbstat, LBGstat" /AntisenseName="sapB" /AntisenseCor="-0.57665624439942198" /AntisenseRegPval="-24.5" /CDS_PredictionProba="NA" /TUshortSig="NA" /TUshortPSig="NA" /TUlongSig="NA" /TUlongPSig="NA" /label="S235" CDS complement(726035..726733) /gene="sapB" /locus_tag="BSU_06650" /old_locus_tag="BSU06650" /function="16.1: Circulate" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 410907, 9043134, 14708580, 27350030, 28181542; Product type t : transporter" /codon_start=1 /transl_table=11 /product="putative magnesium transporter" /protein_id="NP_388547.1" /db_xref="EnsemblGenomes-Gn:BSU06650" /db_xref="EnsemblGenomes-Tr:CAB12485" /db_xref="GOA:Q45514" /db_xref="InterPro:IPR003416" /db_xref="SubtiList:BG11845" /db_xref="UniProtKB/Swiss-Prot:Q45514" /translation="MLLSWYIDPDILLKLGIATLIGMVIGLERELKNKPLGLKTCIVI AVSSCMLTIVSINAAYHFPKYYRIMMDPLRLPAQIISGVGFIGAGVILRKSNDVISGL TTSAMIWGAAGLGLATGAGFYKEAFASLLFILISVEFLPWVVRKIGPDRLQEKDIRIR MSLSDKDKMTEILKEMKRRDIKAHSVRIDDLGEKDFPIMEVKVRVHKNRYTTDVYYDI KAIEGVVGVKCDTL*" gene complement(726035..726733) /gene="sapB" /locus_tag="BSU_06650" /old_locus_tag="BSU06650" downshifts complement(726056) /Source="Nicolas_upshifts" /id="D329" /incds=0 /nref=26 /ntot=129 /MaxReadThrough="2.5379" /MaxDrop="3.83708" /score="20.8493264" /energy="-16.2" /TU="NA" /idTUdmin="U511" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(726753..726771) /Source="Nicolas_upshift_promotors" /id="U511" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.684315684315684" /psig="0.684315684315684" /xcortree=1465 /SigmaFactorBS="aagccatcaagcgcagcttggtggcttttgtgctcttgtttt GCTATAaatactgtgagaaaaTCATATTTATTTAAAAACAccatagagaagggggaag t" /listShort="sapB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(726774) /Source="Nicolas_upshifts" /id="U511" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.684315684315684" /psig="0.684315684315684" /xcortree=1465 /SigmaFactorBS="aagccatcaagcgcagcttggtggcttttgtgctcttgtttt GCTATAaatactgtgagaaaaTCATATTTATTTAAAAACAccatagagaagggggaag t" /listShort="sapB" /GFF_Attribute="listLong" promotor_-35 complement(726787..726792) /Source="Nicolas_upshift_promotors" /id="U511" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.684315684315684" /psig="0.684315684315684" /xcortree=1465 /SigmaFactorBS="aagccatcaagcgcagcttggtggcttttgtgctcttgtttt GCTATAaatactgtgagaaaaTCATATTTATTTAAAAACAccatagagaagggggaag t" /listShort="sapB" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(726840..728318) /gene="opuE" /locus_tag="BSU_06660" /old_locus_tag="BSU06660" /function="16.8: Protect" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:9701821, 11902719, 14996799, 15849754, 16850406, 17183215, 22685134" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9701821, 11902719, 14996799, 15849754, 16850406, 17183215, 22685134; Product type t: transporter" /codon_start=1 /transl_table=11 /product="proline transporter" /protein_id="NP_388548.1" /db_xref="EnsemblGenomes-Gn:BSU06660" /db_xref="EnsemblGenomes-Tr:CAB12486" /db_xref="GOA:O06493" /db_xref="InterPro:IPR001734" /db_xref="InterPro:IPR011851" /db_xref="InterPro:IPR018212" /db_xref="SubtiList:BG12641" /db_xref="UniProtKB/Swiss-Prot:O06493" /translation="MSIEIIISLGIYFIAMLLIGWYAFKKTTDINDYMLGGRGLGPFV TALSAGAADMSGWMLMGVPGAMFATGLSTLWLALGLTIGAYSNYLLLAPRLRAYTEAA DDAITIPDFFDKRFQHSSSLLKIVSALIIMIFFTLYTSSGMVSGGRLFESAFGADYKL GLFLTTAVVVLYTLFGGFLAVSLTDFVQGAIMFAALVLVPIVAFTHVGGVAPTFHEID AVNPHLLDIFKGASVISIISYLAWGLGYYGQPHIIVRFMAIKDIKDLKPARRIGMSWM IITVLGSVLTGLIGVAYAHKFGVAVKDPEMIFIIFSKILFHPLITGFLLSAILAAIMS SISSQLLVTASAVTEDLYRSFFRRKASDKELVMIGRLSVLVIAVIAVLLSLNPNSTIL DLVGYAWAGFGSAFGPAILLSLYWKRMNEWGALAAMIVGAATVLIWITTGLAKSTGVY EIIPGFILSMIAGIIVSMITKRPAKASYRLFGVMEKLLKRKK*" gene complement(726840..728318) /gene="opuE" /locus_tag="BSU_06660" /old_locus_tag="BSU06660" downshifts complement(726854) /Source="Nicolas_upshifts" /id="D330" /incds=0 /nref=43 /ntot=142 /MaxReadThrough="5.35634" /MaxDrop="4.34381" /score="9.43100511" /energy="-13.8" /TU="U512,U513" /idTUdmin="U511" /TUdmin="-798" /isTUend="FALSE" upshifts complement(727706) /Source="Nicolas_upshifts" /id="U512" /multdbtbs="-" /comp="M18" /sig="Sig-" /pcomp="0.475524475524476" /psig="0.475524475524476" /xcortree=138 /SigmaFactorBS="gacttcgtgcagggtgcgatcatgtttgcagcactagtgctt gtGCCGATCGTTGCTTttacccatgtgggcggcgttgctccgactttccatgaaatcg a" /listShort="sapB" /GFF_Attribute="listLong" misc_feature complement(727709..727722) /Source="Nicolas_upshift_promotors" /id="U512" /multdbtbs="-" /comp="M18" /sig="Sig-" /pcomp="0.475524475524476" /psig="0.475524475524476" /xcortree=138 /SigmaFactorBS="gacttcgtgcagggtgcgatcatgtttgcagcactagtgctt gtGCCGATCGTTGCTTttacccatgtgggcggcgttgctccgactttccatgaaatcg a" /listShort="sapB" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" S_feature complement(728319..728449) /Source="Nicolas_S_feature" /locus_tag="new_728319_728449_c" /HighExp="Salt, HiOs, Etha, Gly, MG 25, MG 45, M9-exp, MG t5, MG 15, GM 5" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigB" /TUshortPSig="0.954" /TUlongSig="NA" /TUlongPSig="NA" /label="S236" promotor_-10 complement(728440..728458) /Source="Nicolas_upshift_promotors" /id="U513" /multdbtbs="SigA,SigB" /comp="M11" /sig="SigB" /pcomp="0.954045954045954" /psig="0.954045954045954" /xcortree=137 /SigmaFactorBS="tttgcaacggtatttccagcttatgatcaaTGTTTCAtcgct tgaatggccGGGAATACTTTGTTAGGTTaagttaccaagtgcacccgcaaaagaattt c" /listShort="S236, opuE, sapB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(728449) /Source="Nicolas_upshifts" /id="U513" /multdbtbs="SigA,SigB" /comp="M11" /sig="SigB" /pcomp="0.954045954045954" /psig="0.954045954045954" /xcortree=137 /SigmaFactorBS="tttgcaacggtatttccagcttatgatcaaTGTTTCAtcgct tgaatggccGGGAATACTTTGTTAGGTTaagttaccaagtgcacccgcaaaagaattt c" /listShort="S236, opuE, sapB" /GFF_Attribute="listLong" promotor_-35 complement(728473..728479) /Source="Nicolas_upshift_promotors" /id="U513" /multdbtbs="SigA,SigB" /comp="M11" /sig="SigB" /pcomp="0.954045954045954" /psig="0.954045954045954" /xcortree=137 /SigmaFactorBS="tttgcaacggtatttccagcttatgatcaaTGTTTCAtcgct tgaatggccGGGAATACTTTGTTAGGTTaagttaccaagtgcacccgcaaaagaattt c" /listShort="S236, opuE, sapB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 728580..728583 /Source="Nicolas_upshift_promotors" /id="U514" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.88011988011988" /psig="0.999000999001" /xcortree=2562 /SigmaFactorBS="ttcaaaaaataattaaagtaaaaatattcagaaaaatatttc GTTTctccttctcctcatttTAGTATAAAATATATAGGGTattgtttcgaaaacacag g" /listShort="S237, gatC, gatA, gatB" /GFF_Attribute="listLong" /label="promotor_-35" S_feature 728598..728731 /Source="Nicolas_S_feature" /locus_tag="new_728598_728731" /HighExp="G180, G150, LBGexp, Oxctl, Paraq, dia0, G135, Lbexp, H2O2, LBGtran" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S237" upshifts 728598 /Source="Nicolas_upshifts" /id="U514" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.88011988011988" /psig="0.999000999001" /xcortree=2562 /SigmaFactorBS="ttcaaaaaataattaaagtaaaaatattcagaaaaatatttc GTTTctccttctcctcatttTAGTATAAAATATATAGGGTattgtttcgaaaacacag g" /listShort="S237, gatC, gatA, gatB" /GFF_Attribute="listLong" promotor_-10 728600..728619 /Source="Nicolas_upshift_promotors" /id="U514" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.88011988011988" /psig="0.999000999001" /xcortree=2562 /SigmaFactorBS="ttcaaaaaataattaaagtaaaaatattcagaaaaatatttc GTTTctccttctcctcatttTAGTATAAAATATATAGGGTattgtttcgaaaacacag g" /listShort="S237, gatC, gatA, gatB" /GFF_Attribute="listLong" /label="promotor_-10" CDS 728732..729022 /gene="gatC" /locus_tag="BSU_06670" /old_locus_tag="BSU06670" /EC_number="6.3.5.7" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:9342321, 11445070, 12682299, 25005615" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9342321, 11445070, 12682299, 25005615; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="glutamyl-tRNA(Gln) amidotransferase (subunit C)" /protein_id="NP_388549.1" /db_xref="EnsemblGenomes-Gn:BSU06670" /db_xref="EnsemblGenomes-Tr:CAB12487" /db_xref="GOA:O06492" /db_xref="InterPro:IPR003837" /db_xref="InterPro:IPR036113" /db_xref="SubtiList:BG12838" /db_xref="UniProtKB/Swiss-Prot:O06492" /translation="MSRISIEEVKHVAHLARLAITEEEAKMFTEQLDSIISFAEELNE VNTDNVEPTTHVLKMKNVMREDEAGKGLPVEDVMKNAPDHKDGYIRVPSILD*" gene 728732..729022 /gene="gatC" /locus_tag="BSU_06670" /old_locus_tag="BSU06670" CDS 729038..730495 /gene="gatA" /locus_tag="BSU_06680" /old_locus_tag="BSU06680" /EC_number="6.3.5.7" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:11445070, 12682299, 9342321" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11445070, 12682299, 9342321; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="glutamyl-tRNA(Gln) amidotransferase (subunit A)" /protein_id="NP_388550.1" /db_xref="EnsemblGenomes-Gn:BSU06680" /db_xref="EnsemblGenomes-Tr:CAB12488" /db_xref="GOA:O06491" /db_xref="InterPro:IPR000120" /db_xref="InterPro:IPR004412" /db_xref="InterPro:IPR020556" /db_xref="InterPro:IPR023631" /db_xref="InterPro:IPR036928" /db_xref="SubtiList:BG12839" /db_xref="UniProtKB/Swiss-Prot:O06491" /translation="MSLFDHKITELKQLIHKKEIKISDLVDESYKRIQAVDDKVQAFL ALDEERARAYAKELDEAVDGRSEHGLLFGMPIGVKDNIVTKGLRTTCSSKILENFDPI YDATVVQRLQDAEAVTIGKLNMDEFAMGSSTENSAYKLTKNPWNLDTVPGGSSGGSAA AVAAGEVPFSLGSDTGGSIRQPASFCGVVGLKPTYGRVSRYGLVAFASSLDQIGPITR TVEDNAFLLQAISGVDKMDSTSANVDVPDFLSSLTGDIKGLKIAVPKEYLGEGVGKEA RESVLAALKVLEGLGATWEEVSLPHSKYALATYYLLSSSEASANLARFDGIRYGYRTD NADNLIDLYKQTRAEGFGNEVKRRIMLGTFALSSGYYDAYYKKAQKVRTLIKKDFEDV FEKYDVIVGPTTPTPAFKIGENTKDPLTMYANDILTIPVNLAGVPGISVPCGLADGLP LGLQIIGKHFDESTVYRVAHAFEQATDHHKAKPEL*" gene 729038..730495 /gene="gatA" /locus_tag="BSU_06680" /old_locus_tag="BSU06680" CDS 730509..731939 /gene="gatB" /locus_tag="BSU_06690" /old_locus_tag="BSU06690" /EC_number="6.3.5.7" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:11445070, 12682299, 9342321" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11445070, 12682299, 9342321; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="glutamyl-tRNA(Gln) amidotransferase (subunit B)" /protein_id="NP_388551.2" /db_xref="EnsemblGenomes-Gn:BSU06690" /db_xref="EnsemblGenomes-Tr:CAB12489" /db_xref="GOA:O30509" /db_xref="InterPro:IPR003789" /db_xref="InterPro:IPR004413" /db_xref="InterPro:IPR006075" /db_xref="InterPro:IPR014746" /db_xref="InterPro:IPR017958" /db_xref="InterPro:IPR017959" /db_xref="InterPro:IPR018027" /db_xref="InterPro:IPR023168" /db_xref="SubtiList:BG12840" /db_xref="UniProtKB/Swiss-Prot:O30509" /translation="MNFETVIGLEVHVELKTKSKIFSSSPTPFGAEANTQTSVIDLGY PGVLPVLNKEAVEFAMKAAMALNCEIATDTKFDRKNYFYPDNPKAYQISQFDKPIGEN GWIEIEVGGKTKRIGITRLHLEEDAGKLTHTGDGYSLVDFNRQGTPLVEIVSEPDIRT PEEAYAYLEKLKSIIQYTGVSDCKMEEGSLRCDANISLRPIGQEEFGTKTELKNLNSF AFVQKGLEHEEKRQEQVLLSGGVIQQETRRYDEATKKTILMRVKEGSDDYRYFPEPDL VELYIDDEWKERVKASIPELPDERRKRYIEELGLPAYDAMVLTLTKEMADFFEETVQK GAEAKQASNWLMGEVSAYLNAEQKELADVALTPEGLAGMIKLIEKGTISSKIAKKVFK ELIEKGGDAEKIVKEKGLVQISDEGVLLKLVTEALDNNPQSIEDFKNGKDRAIGFLVG QIMKASKGQANPPMVNKILLEEIKKR*" gene 730509..731939 /gene="gatB" /locus_tag="BSU_06690" /old_locus_tag="BSU06690" downshifts 731920 /Source="Nicolas_upshifts" /id="D331" /incds=0 /nref=257 /ntot=266 /MaxReadThrough="1.62334" /MaxDrop="8.77378" /score="26.1218607" /energy="-9.6" /TU="NA" /idTUdmin="U514" /TUdmin=0 /isTUend="TRUE" CDS complement(731954..732823) /gene="yerO" /locus_tag="BSU_06700" /old_locus_tag="BSU06700" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative transcriptional regulator (TetR/AcrR family)" /protein_id="NP_388552.1" /db_xref="EnsemblGenomes-Gn:BSU06700" /db_xref="EnsemblGenomes-Tr:CAB12490" /db_xref="GOA:O31500" /db_xref="InterPro:IPR001647" /db_xref="InterPro:IPR009057" /db_xref="InterPro:IPR023772" /db_xref="SubtiList:BG12841" /db_xref="UniProtKB/Swiss-Prot:O31500" /translation="MNEKKERIIKTSIRLFAKKGFAATTIQEIASECGISKGAFYLHF KSKEALLLSACEYYIGMSMNKMKNIEEDLAGKPPKEVLKKQIGAQFEDFRDHKDFIVL LLTENIIPENQEIKQYFYKVTMETDKLYRNALLVSYGEGIERYVADLSIMARGIVHSY MNVMVFNGELNIDAEEISAFIIERLDDLVQGLSRSALNPIVSKDIFNPMPAGKDQLLE DIQKVKENSTLPEDITVSLDVIEEELTQDKPRKPIIKGMLSNLAGTNDKEVERLRALI LSLSQFDHKKSSL*" gene complement(731954..732823) /gene="yerO" /locus_tag="BSU_06700" /old_locus_tag="BSU06700" downshifts complement(731996) /Source="Nicolas_upshifts" /id="D332" /incds=0 /nref=122 /ntot=211 /MaxReadThrough="2.21801" /MaxDrop="4.89305" /score="32.2694333" /energy="-11.4" /TU="NA" /idTUdmin="U517" /TUdmin=0 /isTUend="TRUE" promotor_-35 732613..732618 /Source="Nicolas_upshift_promotors" /id="U515" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.822177822177822" /psig="0.822177822177822" /xcortree=1398 /SigmaFactorBS="ccttaggcggctttccggcgagatcttCTTCTAtatttttca ttttgtTCATAGACATACCGATATAatattcacaggcagataacagcagcgcttcttt c" /GFF_Attribute="listShort" /listLong="swrC" /label="promotor_-35" promotor_-10 732634..732652 /Source="Nicolas_upshift_promotors" /id="U515" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.822177822177822" /psig="0.822177822177822" /xcortree=1398 /SigmaFactorBS="ccttaggcggctttccggcgagatcttCTTCTAtatttttca ttttgtTCATAGACATACCGATATAatattcacaggcagataacagcagcgcttcttt c" /GFF_Attribute="listShort" /listLong="swrC" /label="promotor_-10" upshifts 732646 /Source="Nicolas_upshifts" /id="U515" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.822177822177822" /psig="0.822177822177822" /xcortree=1398 /SigmaFactorBS="ccttaggcggctttccggcgagatcttCTTCTAtatttttca ttttgtTCATAGACATACCGATATAatattcacaggcagataacagcagcgcttcttt c" /GFF_Attribute="listShort" /listLong="swrC" S_feature complement(732824..732898) /Source="Nicolas_S_feature" /locus_tag="new_732824_732898_c" /HighExp="C30, S1, T3.0H, T4.0H, Salt, T5.0H, T2.0H, T3.30H, MG 150, T2.30H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S238" promotor_-35 732876..732883 /Source="Nicolas_upshift_promotors" /id="U516" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.679320679320679" /psig="0.998001998001998" /xcortree=3014 /SigmaFactorBS="taatccttgaaaaatttagtaaaattttctggtatatgAGTT GACGttgttgcgttataacGTTTAGTATTATATAGAATGaccagtcagtcaataaaaa a" /listShort="swrC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(732892..732911) /Source="Nicolas_upshift_promotors" /id="U517" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.995004995004995" /psig=1 /xcortree=3036 /SigmaFactorBS="acgtggttcatcatatcctccattacatttttTATTGACTga ctggtcattctaTATAATACTAAACGTTATAAcgcaacaacgtcaactcatataccag a" /listShort="S238, yerO" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 732898 /Source="Nicolas_upshifts" /id="U516" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.679320679320679" /psig="0.998001998001998" /xcortree=3014 /SigmaFactorBS="taatccttgaaaaatttagtaaaattttctggtatatgAGTT GACGttgttgcgttataacGTTTAGTATTATATAGAATGaccagtcagtcaataaaaa a" /listShort="swrC" /GFF_Attribute="listLong" promotor_-10 732899..732918 /Source="Nicolas_upshift_promotors" /id="U516" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.679320679320679" /psig="0.998001998001998" /xcortree=3014 /SigmaFactorBS="taatccttgaaaaatttagtaaaattttctggtatatgAGTT GACGttgttgcgttataacGTTTAGTATTATATAGAATGaccagtcagtcaataaaaa a" /listShort="swrC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(732905) /Source="Nicolas_upshifts" /id="U517" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.995004995004995" /psig=1 /xcortree=3036 /SigmaFactorBS="acgtggttcatcatatcctccattacatttttTATTGACTga ctggtcattctaTATAATACTAAACGTTATAAcgcaacaacgtcaactcatataccag a" /listShort="S238, yerO" /GFF_Attribute="listLong" promotor_-35 complement(732926..732933) /Source="Nicolas_upshift_promotors" /id="U517" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.995004995004995" /psig=1 /xcortree=3036 /SigmaFactorBS="acgtggttcatcatatcctccattacatttttTATTGACTga ctggtcattctaTATAATACTAAACGTTATAAcgcaacaacgtcaactcatataccag a" /listShort="S238, yerO" /GFF_Attribute="listLong" /label="promotor_-35" CDS 732955..736113 /gene="srfP" /locus_tag="BSU_06710" /old_locus_tag="BSU06710" /function="16.1: Circulate" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:11709341, 15066026, 15941986, 25366377" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11709341, 15066026, 15941986, 25366377; Product type t: transporter" /codon_start=1 /transl_table=11 /product="surfactin exporter involved in surfactin self-resistance" /protein_id="NP_388553.2" /db_xref="EnsemblGenomes-Gn:BSU06710" /db_xref="EnsemblGenomes-Tr:CAB12491" /db_xref="GOA:O31501" /db_xref="InterPro:IPR001036" /db_xref="InterPro:IPR027463" /db_xref="SubtiList:BG12842" /db_xref="UniProtKB/Swiss-Prot:O31501" /translation="MNHVINFVLKNKFAVWLMTIIVTAAGLYAGMNMKQESIPDVNMP YLTISTTYPGATPSQVADEVTKPVEQAVQNLDGVSVVTSTSYENASSVMIEYDYEKDM DKAKTEAAEALENVNLPDDAKDPEISRYSLNSFPILTLSVSSDKDNLQELTKQVEDSL VSKLEGIEGVASVQVSGQQVEEVEFSFKEDKLKEYGLDEDTVKQVIQGSDVTTPLGLY TFGNEEKSVVVSGDIETIKDLKNMRIPTASASSAGSSAASQAGAQSAQAAQSAQAAAQ VQQSASTAVPTVKLSDIATIKDVKKAESVSRTNGKDSIGINIVKANDANTVEVADDVK AELKKFKEDHKGFNYSATLDMAEPITQSVDTMLSKAIFGAIFAIVIILLFLRDIKSTL ISVVSIPLSLLIALLVLQQLDITLNIMTLGAMTVAIGRVVDDSIVVIENIYRRMRLKD EPLRGKALVREATKEMFKPIMSSTIVTIAVFLPLALVGGQIGELFIPFALTIVFALAA SLVISITLVPMLAHSLFKKSLTGAPIKAKEHKPGRLANIYKKVLNWALSHKWITSIIA VLMLLGSLFLVPLIGASYLPSEEEKTMQLTYSPEPGETKKEAENEAEKAEKILLDRKH VDTVQYSLGSGSPLAGGDSNGALFYIKYESDTPDFDKEKDNVLKEIQKQSDRGEWKSQ DFSSSGNNNELTYYVYGDSENDIKDTVKDIEKIMKDEKDLKNVNSGLSSTYDEYTFVA DQEKLSKLGLTASQISQALMSQTSQEPLTTVKKDGKELDVNIKTEKDEYKSVKDLENK KITSATGQEVKIGDVAKVKEGSTSDTVSKRDGKVYADVTGEVTSDNVTAVSAAIQKKI DKLDHPDNVSIDTGGVSADIADSFTKLGLAMLAAIAIVYLVLVITFGGALAPFAILFS LPFTVIGALVGLYVSGETISLNAMIGMLMLIGIVVTNAIVLIDRVIHKEAEGLSTREA LLEAGSTRLRPILMTAIATIGALIPLALGFEGGSQVISKGLGVTVIGGLISSTLLTLL IVPIVYEVLAKFRKKKPGTEEE*" gene 732955..736113 /gene="srfP" /locus_tag="BSU_06710" /old_locus_tag="BSU06710" downshifts 736100 /Source="Nicolas_upshifts" /id="D333" /incds=0 /nref=76 /ntot=243 /MaxReadThrough="3.70478" /MaxDrop="4.6624" /score="-3.65521193" /energy="-12.7" /TU="U516" /idTUdmin="U516" /TUdmin="-110" /isTUend="FALSE" promotor_-35 736352..736355 /Source="Nicolas_upshift_promotors" /id="U518" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.758241758241758" /psig="0.999000999001" /xcortree=2594 /SigmaFactorBS="tgtgcgttttcacctgtaagattatgtacattttGTTGcgat ttttttaactCATAGTATAATTAAAGGTTGttagtgtaaaaatggatcggatactctt a" /listShort="dagK, S239, yefA, S240, S241, yefC, S242, yeeA, yeeB, S243, yeeC, S244" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 736370..736389 /Source="Nicolas_upshift_promotors" /id="U518" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.758241758241758" /psig="0.999000999001" /xcortree=2594 /SigmaFactorBS="tgtgcgttttcacctgtaagattatgtacattttGTTGcgat ttttttaactCATAGTATAATTAAAGGTTGttagtgtaaaaatggatcggatactctt a" /listShort="dagK, S239, yefA, S240, S241, yefC, S242, yeeA, yeeB, S243, yeeC, S244" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 736378 /Source="Nicolas_upshifts" /id="U518" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.758241758241758" /psig="0.999000999001" /xcortree=2594 /SigmaFactorBS="tgtgcgttttcacctgtaagattatgtacattttGTTGcgat ttttttaactCATAGTATAATTAAAGGTTGttagtgtaaaaatggatcggatactctt a" /listShort="dagK, S239, yefA, S240, S241, yefC, S242, yeeA, yeeB, S243, yeeC, S244" /GFF_Attribute="listLong" CDS 736436..737347 /gene="dagK" /locus_tag="BSU_06720" /old_locus_tag="BSU06720" /EC_number="2.7.1.107" /function="16.6: Maintain" /function="16.2: Construct biomass (Anabolism)" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:10220166, 12682299, 17535816, 22224599, 24700682" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10220166, 12682299, 17535816, 22224599, 24700682; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="diacylglycerol kinase" /protein_id="NP_388554.1" /db_xref="EnsemblGenomes-Gn:BSU06720" /db_xref="EnsemblGenomes-Tr:CAB12492" /db_xref="GOA:O31502" /db_xref="InterPro:IPR001206" /db_xref="InterPro:IPR005218" /db_xref="InterPro:IPR016064" /db_xref="InterPro:IPR017438" /db_xref="SubtiList:BG12843" /db_xref="UniProtKB/Swiss-Prot:O31502" /translation="MKRARIIYNPTSGREIFKKHLAQVLQKFEQAGYETSTHATTCAG DATHAAKEAALREFDLIIAAGGDGTINEVVNGLAPLDNRPTLGVIPVGTTNDFARALG IPREDILKAADTVINGVARPIDIGQVNGQYFINIAGGGRLTELTYDVPSKLKTMLGQL AYYLKGMEMLPSLRPTEVEIEYDGKLFQGEIMLFLVTLTNSVGGFEKLAPDSSLNDGM FDLMILKKANLAEFIRVATMALRGEHINDQHIIYTKANRVKVNVSEKMQLNLDGEYGG MLPGEFVNLYRHIHVVMPKEKAEQLDD*" gene 736436..737347 /gene="dagK" /locus_tag="BSU_06720" /old_locus_tag="BSU06720" S_feature 737348..737602 /Source="Nicolas_S_feature" /locus_tag="new_737348_737602" /HighExp="H2O2, Oxctl, Paraq, G180, Cold, C30, G150, G135, Heat, LBGstat" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S239" CDS 737603..738982 /gene="rlmCD" /locus_tag="BSU_06730" /old_locus_tag="BSU06730" /EC_number="2.1.1.189" /EC_number="2.1.1.190" /function="16.8: Protect" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:21824914" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 21824914; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="methyltransferase of m5U747 and m5U1939 in 23S RNA" /protein_id="NP_388555.1" /db_xref="EnsemblGenomes-Gn:BSU06730" /db_xref="EnsemblGenomes-Tr:CAB12493" /db_xref="GOA:O31503" /db_xref="InterPro:IPR001566" /db_xref="InterPro:IPR002792" /db_xref="InterPro:IPR010280" /db_xref="InterPro:IPR012340" /db_xref="InterPro:IPR029063" /db_xref="InterPro:IPR030390" /db_xref="InterPro:IPR030391" /db_xref="SubtiList:BG12826" /db_xref="UniProtKB/Swiss-Prot:O31503" /translation="MKMKPPVEKNEYYDVTFEDLTHEGAGVAKVQGFPIFVPNALPEE KAQIKVTRVKKGFAFGRLIELKEESPHRTDAPCPIYKQCGGCQLQHMTYEGQLLFKQK QVKDVLERIGKLDLSKVTVHPTLGMEDPWNYRNKAQVPVGEREGGLVAGFYQQRSHDI IDMSACLIQQSKNDEAVQAVKDICANYGVKAYNEERHKGWLRHIMVRYGVVTGEMMIV FITRTSDFPHKAKIIEDITAQFPHVKSIVQNINPNKTNVIFGNETNVIWGEEYIYDLI GDVKFAISARSFYQVNPEQTKVLYDKALEYAELQGEETVIDAYCGIGTISLFLAKQAK KVYGVEIVPEAIEDAKRNAELNGNTNAEFAVGEAETVIPKWYEEGITADTLVVDPPRK GCDEALLRTIVEMKPKRVVYVSCNPGTLARDLRVLEDGGYVTREVQPVDMFPHTNHVE CCVLIKLKE*" gene 737603..738982 /gene="rlmCD" /locus_tag="BSU_06730" /old_locus_tag="BSU06730" S_feature 738983..739575 /Source="Nicolas_S_feature" /locus_tag="new_738983_739575" /HighExp="Cold, H2O2, G135, G150, Oxctl, G180, C30, Paraq, LPh, HPh" /AntisenseName="yefB" /AntisenseCor="0.24913678485492899" /AntisenseRegPval="-4.4000000000000004" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S240" CDS complement(738995..739897) /gene="yefB" /locus_tag="BSU_06740" /old_locus_tag="BSU06740" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 1779754, 1762151; Product type h: extrachromosomal origin" /codon_start=1 /transl_table=11 /product="putative site-specific recombinase / invertase; HGT island" /protein_id="NP_388556.1" /db_xref="EnsemblGenomes-Gn:BSU06740" /db_xref="EnsemblGenomes-Tr:CAB12494" /db_xref="GOA:O34574" /db_xref="InterPro:IPR011109" /db_xref="InterPro:IPR025827" /db_xref="SubtiList:BG12827" /db_xref="UniProtKB/Swiss-Prot:O34574" /translation="MYNEGVTSPSQLARKKNATDKWHGSSIRKILENPHYTGTLQQCR EYRPSVTSKRRRSVNLENQIIIEKSHEPIIPLEDFLIVQEILITRKRRRPQAEVHLFT NTAVCKDCRRSMHFKKNRKGYVCGSYNKHGLKACSDHYVSEIDLTDKVITNLNKIYLK FSKENYFKELSEKALKYKEKIESKIIEINEKLNDKKRDKSNLVISLANGVISKEDYQL AINITNEDISNFETTLHQLSKDLEFQKIEKEIIDFKKSLDKFMKEGTLTPEMLHLLVD EIEVHANGTIEINYRFREPTVPSA*" gene complement(738995..739897) /gene="yefB" /locus_tag="BSU_06740" /old_locus_tag="BSU06740" downshifts 739532 /Source="Nicolas_upshifts" /id="D334" /incds=1 /nref=1 /ntot=30 /MaxReadThrough="4.70474" /MaxDrop="2.82299" /score="-8.81916201" /energy="-8.8" /TU="U518" /idTUdmin="U516" /TUdmin=3322 /isTUend="FALSE" S_feature 739577..739877 /Source="Nicolas_S_feature" /locus_tag="new_739577_739877" /HighExp="H2O2, Cold, G180, G135, G150, Paraq, Oxctl, C30, LPh, LBGexp" /AntisenseName="yefB" /AntisenseCor="0.202214664414261" /AntisenseRegPval="-3.1" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S241" CDS 739878..740213 /gene="yefC" /locus_tag="BSU_06750" /old_locus_tag="BSU06750" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative resolvase; HGT island" /protein_id="NP_388557.2" /db_xref="EnsemblGenomes-Gn:BSU06750" /db_xref="EnsemblGenomes-Tr:CAB12495" /db_xref="GOA:O35034" /db_xref="InterPro:IPR006119" /db_xref="InterPro:IPR009057" /db_xref="InterPro:IPR036162" /db_xref="SubtiList:BG12828" /db_xref="UniProtKB/Swiss-Prot:O35034" /translation="MTPSLYNPLAIASKPFPAIYSEKILIFTIFSAFAEFERDMIVER TQEGKMLAKQNPDFREGRPKKFTKQQINHALTLLENHSYKQVEDMTGISVSTLVRAKK KKAAEAING*" gene 739878..740213 /gene="yefC" /locus_tag="BSU_06750" /old_locus_tag="BSU06750" S_feature 740214..740287 /Source="Nicolas_S_feature" /locus_tag="new_740214_740287" /HighExp="G180, H2O2, G150, Cold, G135, Paraq, Oxctl, C30, LPh, dia0" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S242" CDS 740288..742927 /gene="yeeA" /locus_tag="BSU_06760" /old_locus_tag="BSU06760" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative restriction type II methylase; HGT island" /protein_id="NP_388558.1" /db_xref="EnsemblGenomes-Gn:BSU06760" /db_xref="EnsemblGenomes-Tr:CAB12496" /db_xref="GOA:O31504" /db_xref="InterPro:IPR029063" /db_xref="SubtiList:BG12818" /db_xref="UniProtKB/Swiss-Prot:O31504" /translation="MALIDLEDKIAEIVNREDHSDFLYELLGVYDVPRATITRLKKGN QNLTKRVGEVHLKNKVWFKEAKKGKLFDALIDIEQQVEYLSAKPRYLLVTDYDGVLAK DTKTLEALDVKFEELPQYFDFFLAWKGIEKVEFEKENPADIKAAERFARIYDVLRKEN NIIETNRGLDLFLIRLLFCFFAEDTDIFKRNSFTNLIKTLTEEDGSNLNKLFADLFIV LDKNERDDVPSYLKEFPYVNGQLFTEPHTELEFSAKSRKLIIECGELLNWAKINPDIF GSMIQAVASEESRSYLGMHYTSVPNIMKVIKPLFLDKLNQSFLDAYDDYTKLENLLTR IGKIKFFDPACGSGNFLIITYKELRRMEINIIKRLQELLGEYLYVPSVTLSQFYGIEI EDFAHDVAKLSLWIAEHQMNEELKNEVHNAVRPTLPLHTAGDIRCANAIRVEWTEVCP AQGSEEVYVFGNPPYLGSKKQNKEHKSDMLSIFGKVKNGKMLDYISAWFYFGAKYAST TNAKVAFVSTNSVTQGEQVSILWNELFKFGIQINFAYKSFKWANNAKNNAAVIVVIVG FGPLDTKVNKYLFVDETKKLVSNISPYLTDGENILVSSRTKPISDLPKLHFGNMPNDG GGLLFTITEYTDAINKYPELVPYFKKFIGSVEFINGGLRYCLWLNEAKYEKIKSNPLI QERISISKNHREKSTDKGTNKLALTPWKFRDTHETTNYSIVVPSVSSENRFYIPMGLA GADTILSNLIYVIYDAEIYLLGILMSRMHMTWVKAVAGRLKTDYRYSAGLCYNTFPIP ELSTRRKNEIEEAILEILDLREEQGGTLAELYNPSTMPIELKVAHEKLDGIVERAYRQ KQFESDEERLEVLLKLYQEMTER*" gene 740288..742927 /gene="yeeA" /locus_tag="BSU_06760" /old_locus_tag="BSU06760" CDS 742939..744738 /gene="yeeB" /locus_tag="BSU_06770" /old_locus_tag="BSU06770" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative DNA helicase / endonuclease; HGT island" /protein_id="NP_388559.2" /db_xref="EnsemblGenomes-Gn:BSU06770" /db_xref="EnsemblGenomes-Tr:CAB12497" /db_xref="GOA:O34469" /db_xref="InterPro:IPR014001" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG12819" /db_xref="UniProtKB/Swiss-Prot:O34469" /translation="MENIIEINYNQTGKSKKTNEYGMREMQARAFEKRNSQYLLVKAP PASGKSRALMFIGLDKLINQGLRKVIVAVPERSIGSSFKNTDLKSYGFFENWKVDPRN NLTVGGDNSKVKSFVRFMESDDQVLICTHSTLRFAFEKIDDKAFDNCLLAIDEFHHVS ADVNSRLGELLRSIIHNSSAHIVAMTGSYFRGDSVPILLPEDEELFDKVTYSYYEQLD GYEYLKGFGIGYHFYQGQYTSAINEVLDTNKKTIVHIPNVNSGESTKDKYDEVGKILD MIGEVEYQDDDTGIIYVKRHSDGKTLKIADLVDDQVGRENVVAYLRNIEALDDLDIII ALGMAKEGFDWPFCEHTLTVGYRGSLTEIVQIIGRCTRDSYNKTYAQFTNLIAMPDAK DEVVTYTVNTMLKAISASLLMEQVLTPDFKFKRRRNESEKSSTTGELFVKGLKEPSTE NVKKIIENDINDLKAKIMQDSQVQKTFSGEVDPKVLNKVLIPKVIQKVYPNLSDEEIE EVRQHVVLDTVMKGAKSEVVGSKEFIRMADKFINIEDLDINLIDSINPFQKAFEVLSK ELNSPVLKLIQETIDAKRINFDEDELVFIWPKV*" gene 742939..744738 /gene="yeeB" /locus_tag="BSU_06770" /old_locus_tag="BSU06770" promotor_-10 complement(743179..743194) /Source="Nicolas_upshift_promotors" /id="U519" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1689 /SigmaFactorBS="cagttaaattatttctaggatcaactttccaattttcaaAGA AACCATAactttttaaatCCGTATTTTTAAATGAagaacctatagagcgttcaggtac a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(743194) /Source="Nicolas_upshifts" /id="U519" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1689 /SigmaFactorBS="cagttaaattatttctaggatcaactttccaattttcaaAGA AACCATAactttttaaatCCGTATTTTTAAATGAagaacctatagagcgttcaggtac a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(743206..743215) /Source="Nicolas_upshift_promotors" /id="U519" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1689 /SigmaFactorBS="cagttaaattatttctaggatcaactttccaattttcaaAGA AACCATAactttttaaatCCGTATTTTTAAATGAagaacctatagagcgttcaggtac a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" S_feature 744739..744850 /Source="Nicolas_S_feature" /locus_tag="new_744739_744850" /HighExp="Cold, G180, G135, G150, H2O2, Paraq, HPh, LPh, Oxctl, BMM" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S243" CDS 744851..745999 /gene="yeeC" /locus_tag="BSU_06780" /old_locus_tag="BSU06780" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; Product type h: extrachromosomal origin" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein; HGT island" /protein_id="NP_388560.2" /db_xref="EnsemblGenomes-Gn:BSU06780" /db_xref="EnsemblGenomes-Tr:CAB12498" /db_xref="InterPro:IPR018306" /db_xref="SubtiList:BG12820" /db_xref="UniProtKB/Swiss-Prot:O34352" /translation="MASNRYHSINEIMESQLFYQITTPPKKTQKAQYDPEVEKFLEII EFVKENGREPQKVPTDLTERSLASRLIGIRKDPDRMEYLKEYDEIGLLEVRSKELTIP KISSIDDILKSGLSALLGDNLNNDITRSIFDTSSLQKVTTMPEYVAKRKKIKDFGKFE ELFKKCHKEITEGKRKILTFKNEQDIQSNSFYILKGVLLYVEDVGERKKAKGKTNARL RCIFENGTESDMLLRSLSAELYKHGRRVTDNEDTLLDNVREDDVSTGFIYVLKSLSTD PQISSIKNLYKIGFTTGSVENRIRNAENQSTYLYAPVEIVTTYQVFNMNASKFETAIH HALANNNLDVSILGANGKMLVPKEWFVVTLEDLQAVIDEIVMMVHLYD*" gene 744851..745999 /gene="yeeC" /locus_tag="BSU_06780" /old_locus_tag="BSU06780" S_feature 746000..747189 /Source="Nicolas_S_feature" /locus_tag="new_746000_747189" /HighExp="Cold, G135, H2O2, G180, G150, LPh, C30, HPh, BMM, Paraq" /AntisenseName="yeeD" /AntisenseCor="-0.41772847620445203" /AntisenseRegPval="-12.1" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S244" CDS complement(746261..746566) /gene="yeeD" /locus_tag="BSU_06790" /old_locus_tag="BSU06790" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein; HGT island" /protein_id="NP_388561.1" /db_xref="EnsemblGenomes-Gn:BSU06790" /db_xref="EnsemblGenomes-Tr:CAB12499" /db_xref="SubtiList:BG12821" /db_xref="UniProtKB/Swiss-Prot:O34950" /translation="MTVRKELIKQINLTITVIKTINQKNPTPMVKNILKRYEEAKEFI LQSSDGKFEEDLSKVRNKLDTLTRAYLESANDYMNPMLKEMHKTEKLLKEYDETTQS* " gene complement(746261..746566) /gene="yeeD" /locus_tag="BSU_06790" /old_locus_tag="BSU06790" CDS complement(746633..746839) /gene="yezA" /locus_tag="BSU_06800" /old_locus_tag="BSU06800" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; Product type h: extrachromosomal origin" /codon_start=1 /transl_table=11 /product="hypothetical protein; HGT island" /protein_id="NP_388562.1" /db_xref="EnsemblGenomes-Gn:BSU06800" /db_xref="EnsemblGenomes-Tr:CAB12500" /db_xref="GOA:O31505" /db_xref="InterPro:IPR000290" /db_xref="InterPro:IPR035900" /db_xref="SubtiList:BG12872" /db_xref="UniProtKB/Swiss-Prot:O31505" /translation="MDKLTKEELIFLVKELMNPTLDDEKVSEYLDLLEKNVPYPAPSD LIFWSNEDYTAEQVVKIALNYKDE*" gene complement(746633..746839) /gene="yezA" /locus_tag="BSU_06800" /old_locus_tag="BSU06800" CDS complement(747079..747534) /gene="yezG" /locus_tag="BSU_06811" /old_locus_tag="BSU06811" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; Product type h: extrachromosomal origin" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein; HGT island" /protein_id="YP_003097692.1" /db_xref="EnsemblGenomes-Gn:BSU06811" /db_xref="EnsemblGenomes-Tr:CAX52579" /db_xref="InterPro:IPR006728" /db_xref="InterPro:IPR036170" /db_xref="UniProtKB/Swiss-Prot:C0H3X4" /translation="MQDLYQLIGEKLNDIIPGEWTKIYLYAEVLDDSTMVLFHFRTPE NNQIIYSQDIPSHYNVSKDIFKTLLRELRELFEELRTEHRNNNDDVWTNLTLTLDRSG EFQLDYNYDDILASELDGYERIAIWEYKNLGILPEDEDDKEFVISYLGL*" gene complement(747079..747534) /gene="yezG" /locus_tag="BSU_06811" /old_locus_tag="BSU06811" downshifts complement(747092) /Source="Nicolas_upshifts" /id="D335" /incds=0 /nref=41 /ntot=213 /MaxReadThrough="4.42275" /MaxDrop="5.23695" /score="10.2582155" /energy="-11.7" /TU="U520,U521" /idTUdmin="U520" /TUdmin="-529" /isTUend="FALSE" CDS complement(747554..749563) /gene="yeeF" /locus_tag="BSU_06812" /old_locus_tag="BSU06812" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type h : extrachromosomal origin" /codon_start=1 /transl_table=11 /product="putative nucleic acid binding protein; HGT island" /protein_id="NP_388563.2" /db_xref="EnsemblGenomes-Gn:BSU06812" /db_xref="EnsemblGenomes-Tr:CAB12501" /db_xref="GOA:O31506" /db_xref="InterPro:IPR006829" /db_xref="SubtiList:BG12822" /db_xref="UniProtKB/Swiss-Prot:O31506" /translation="MKVFEAKTLLSEATDRAKEYKELRTQMVNLRKALKGVADLSDSE FSGKGASNIKAFYHDHVGVADQWIDYIDMKIAFFNSIAGAAEDKGLSDAYIEESFLEH ELANANKKSKSIMSEQKKAMKDILNDIDDILPLDLFSTETFKDELADANDKRKKTLEK LDALDEDLKTEYALSEPNEQFIKSDFQKLQEATGKGKNATPIHYNAKAYRESDIHKKK GDIEKRTEAYLKIKKEEAKEREIEKLKERLKNYDYADADEFYEMAKTIGYENLTAEQQ RYFTQIENTRELEAGFKGVAVGLYDSGKDAVVGLWDMVTDPGGTVEAITGAMAHPIKT YEAISAAIEESYQKDMVNGDTYSRARWVSYAVGTVVTSIVGTKGVGAVSKTGTAAKVT TKVKTAASKSATAQKAITVSKQTVDHIKQKVNTGIEVSKKHVKTKLNQIGDLTLADIL PYHPRHDLVPAGVPYNAVNGVTLKEGLQKFAKVILPKPYGTSSSGRRTPAPHVPPVTV KYGEHFARWSRKKVLKPNIIYKTKEGYTYTTDNYGRITSVKADLQLGEAKRNQYAQTN AGKPQDRKPDDDGGHLIATQFKGSGQFDNIVPMNSQINRSGGKWYEMEQEWAKALSKK PPKKVAVQIEPVYSGDSLRPSYFDVTYKIGSRKEISVSIKNQPGG*" gene complement(747554..749563) /gene="yeeF" /locus_tag="BSU_06812" /old_locus_tag="BSU06812" promotor_-10 complement(747921..747940) /Source="Nicolas_upshift_promotors" /id="U520" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.98101898101898" /psig="0.999000999001" /xcortree=2752 /SigmaFactorBS="aatatcatctacaaaacaaaagaaggctacACGTACacgact gacaacTATGGTAGAATTACAAGTGTcaaagcagacttgcagctgggagaagcgaaac g" /listShort="yezG, yezA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(747928) /Source="Nicolas_upshifts" /id="U520" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.98101898101898" /psig="0.999000999001" /xcortree=2752 /SigmaFactorBS="aatatcatctacaaaacaaaagaaggctacACGTACacgact gacaacTATGGTAGAATTACAAGTGTcaaagcagacttgcagctgggagaagcgaaac g" /listShort="yezG, yezA" /GFF_Attribute="listLong" promotor_-35 complement(747953..747958) /Source="Nicolas_upshift_promotors" /id="U520" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.98101898101898" /psig="0.999000999001" /xcortree=2752 /SigmaFactorBS="aatatcatctacaaaacaaaagaaggctacACGTACacgact gacaacTATGGTAGAATTACAAGTGTcaaagcagacttgcagctgggagaagcgaaac g" /listShort="yezG, yezA" /GFF_Attribute="listLong" /label="promotor_-35" misc_feature complement(749590..749609) /Source="Nicolas_upshift_promotors" /id="U521" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.976023976023976" /psig="0.994005994005994" /xcortree=2985 /SigmaFactorBS="atgactcatttttccaccaaaacacgttctcacccccacctt atcccgaccCGTGGTAAAATTTTGATATTgagcgaacaaaagaagggaaatggtcatg a" /listShort="yeeF, yezG, yezA, yeeD" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(749600) /Source="Nicolas_upshifts" /id="U521" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.976023976023976" /psig="0.994005994005994" /xcortree=2985 /SigmaFactorBS="atgactcatttttccaccaaaacacgttctcacccccacctt atcccgaccCGTGGTAAAATTTTGATATTgagcgaacaaaagaagggaaatggtcatg a" /listShort="yeeF, yezG, yezA, yeeD" /GFF_Attribute="listLong" CDS 749775..750797 /gene="yeeG" /locus_tag="BSU_06820" /old_locus_tag="BSU06820" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative phage receptor protein" /protein_id="NP_388564.2" /db_xref="EnsemblGenomes-Gn:BSU06820" /db_xref="EnsemblGenomes-Tr:CAB12502" /db_xref="GOA:O31507" /db_xref="InterPro:IPR015943" /db_xref="SubtiList:BG12823" /db_xref="UniProtKB/Swiss-Prot:O31507" /translation="MTKKRITFGLLVLMVCVILFVLYVQLRNKDSIPVQSSAIHPEED RIFFIYSNPFIKESVLLSTSTGERFNRRTFKVADVPYIQTKSYASTDLVLLAEHEPFY YTLEKDVIKEHPLSDPFAFWYEGKDVTIEAYNVDTTGNEIHINDRKTKKEYTLTLPPL VTMGASDENFIYIIQSMSIYVIDRKTEEMIETLSLASYADQFADSEEFIVASSDHKLT VIEKGTWKTTYIAYPEDLEYADTVYYDKESGSFYVAYEDKEGGANLLEYGEDFSIHTY SLKFPYMEAKFKGNLLYIVAQEEHKKGIGGYVGVFDIHSKEMLYQFDLPEEQVKVQDF VVVDNK*" gene 749775..750797 /gene="yeeG" /locus_tag="BSU_06820" /old_locus_tag="BSU06820" promotor_-35 750897..750904 /Source="Nicolas_upshift_promotors" /id="U522" /multdbtbs="SigA" /comp="M17" /sig="SigA" /pcomp="0.466533466533467" /psig="0.997002997002997" /xcortree=2961 /SigmaFactorBS="caaattgacaggatgaaaaaacaatttcttccttctatATTG TTTTcaaaatttgggatTGATAGAATATGACATATCTcatagagaaggagggaagccg t" /listShort="rapH, phrH, S245, yeeI" /listLong="yeeK" /label="promotor_-35" promotor_-10 750918..750937 /Source="Nicolas_upshift_promotors" /id="U522" /multdbtbs="SigA" /comp="M17" /sig="SigA" /pcomp="0.466533466533467" /psig="0.997002997002997" /xcortree=2961 /SigmaFactorBS="caaattgacaggatgaaaaaacaatttcttccttctatATTG TTTTcaaaatttgggatTGATAGAATATGACATATCTcatagagaaggagggaagccg t" /listShort="rapH, phrH, S245, yeeI" /listLong="yeeK" /label="promotor_-10" upshifts 750919 /Source="Nicolas_upshifts" /id="U522" /multdbtbs="SigA" /comp="M17" /sig="SigA" /pcomp="0.466533466533467" /psig="0.997002997002997" /xcortree=2961 /SigmaFactorBS="caaattgacaggatgaaaaaacaatttcttccttctatATTG TTTTcaaaatttgggatTGATAGAATATGACATATCTcatagagaaggagggaagccg t" /listShort="rapH, phrH, S245, yeeI" /listLong="yeeK" CDS 750959..752089 /gene="rapH" /locus_tag="BSU_06830" /old_locus_tag="BSU06830" /EC_number="3.1.-.-" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:16553878, 21908671" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16553878, 21908671; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="response regulator aspartate phosphatase" /protein_id="NP_388565.2" /db_xref="EnsemblGenomes-Gn:BSU06830" /db_xref="EnsemblGenomes-Tr:CAB12503" /db_xref="GOA:Q59HN8" /db_xref="InterPro:IPR011990" /db_xref="InterPro:IPR013026" /db_xref="InterPro:IPR019734" /db_xref="PDB:3Q15" /db_xref="SubtiList:BG11031" /db_xref="UniProtKB/Swiss-Prot:Q59HN8" /translation="MSQAIPSSRVGVKINEWYKMIRQFSVPDAEILKAEVEQDIQQME EDQDLLIYYSLMCFRHQLMLDYLEPGKTYGNRPTVTELLETIETPQKKLTGLLKYYSL FFRGMYEFDQKEYVEAIGYYREAEKELPFVSDDIEKAEFHFKVAEAYYHMKQTHVSMY HILQALDIYQNHPLYSIRTIQSLFVIAGNYDDFKHYDKALPHLEAALELAMDIQNDRF IAISLLNIANSYDRSGDDQMAVEHFQKAAKVSREKVPDLLPKVLFGLSWTLCKAGQTQ KAFQFIEEGLDHITARSHKFYKELFLFLQAVYKETVDERKIHDLLSYFEKKNLHAYIE ACARSAAAVFESSCHFEQAAAFYRKVLKAQEDILKGECLYAY*" gene 750959..752089 /gene="rapH" /locus_tag="BSU_06830" /old_locus_tag="BSU06830" CDS 752079..752252 /gene="phrH" /locus_tag="BSU_06839" /old_locus_tag="BSU06839" /experiment="publication(s) with functional evidences, PMID:16553878, 21908671" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16553878, 21908671; Product type r: regulator" /codon_start=1 /transl_table=11 /product="hexapeptide (TDRNTT) inhibitor of regulatory cascade" /protein_id="YP_003097693.1" /db_xref="EnsemblGenomes-Gn:BSU06839" /db_xref="EnsemblGenomes-Tr:CAX52580" /db_xref="GOA:Q59HN7" /db_xref="UniProtKB/Swiss-Prot:Q59HN7" /translation="MPIKKKVMMCLAVTLVFGSMSFPTLTNSGGFKESTDRNTTYIDH SPYKLSDQKKALS*" gene 752079..752252 /gene="phrH" /locus_tag="BSU_06839" /old_locus_tag="BSU06839" downshifts 752207 /Source="Nicolas_upshifts" /id="D336" /incds=0 /nref=3 /ntot=66 /MaxReadThrough="5.5891" /MaxDrop="2.9063" /score="14.5772672" /energy="-7.6" /TU="U522" /idTUdmin="U522" /TUdmin="-901" /isTUend="FALSE" S_feature 752253..752357 /Source="Nicolas_S_feature" /locus_tag="new_752253_752357" /HighExp="S2, G/S, T2.30H, GM 150, T3.0H, T2.0H, S1, T-4.40H, T-2.40H, T3.30H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.997" /TUlongSig="NA" /TUlongPSig="NA" /label="S245" promotor_-35 752324..752331 /Source="Nicolas_upshift_promotors" /id="U523" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.93006993006993" /psig="0.999000999001" /xcortree=1934 /SigmaFactorBS="cattccttctatttctaacgcaagaCACTCGAAacaaccaaa ccattTGAGGTATAATGGATAAAGTgaataacagtatttagattgatatatatgaaag a" /listShort="yeeI, yeeK" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 752346..752365 /Source="Nicolas_upshift_promotors" /id="U523" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.93006993006993" /psig="0.999000999001" /xcortree=1934 /SigmaFactorBS="cattccttctatttctaacgcaagaCACTCGAAacaaccaaa ccattTGAGGTATAATGGATAAAGTgaataacagtatttagattgatatatatgaaag a" /listShort="yeeI, yeeK" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 752359 /Source="Nicolas_upshifts" /id="U523" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.93006993006993" /psig="0.999000999001" /xcortree=1934 /SigmaFactorBS="cattccttctatttctaacgcaagaCACTCGAAacaaccaaa ccattTGAGGTATAATGGATAAAGTgaataacagtatttagattgatatatatgaaag a" /listShort="yeeI, yeeK" /GFF_Attribute="listLong" CDS 752412..753131 /gene="yeeI" /locus_tag="BSU_06840" /old_locus_tag="BSU06840" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative DNA integrase or transcriptional regulator" /protein_id="NP_388566.3" /db_xref="EnsemblGenomes-Gn:BSU06840" /db_xref="EnsemblGenomes-Tr:CAB12504" /db_xref="GOA:O31509" /db_xref="InterPro:IPR002876" /db_xref="InterPro:IPR017856" /db_xref="InterPro:IPR026562" /db_xref="InterPro:IPR026564" /db_xref="InterPro:IPR029072" /db_xref="SubtiList:BG12824" /db_xref="UniProtKB/Swiss-Prot:O31509" /translation="MGRKWNNIKEKKASKDANTSRIYAKFGREIYVAAKQGEPDPESN QALKVVLERAKTYSVPKNIIERAIEKAKGGAEENYDELRYEGFGPNGSMIIVDALTNN VNRTAPEVRAAFGKNGGNMGVSGSVAYMFDATAVIGVEGKTADEALEILMEADVDVRD ILEEDDSAIVYAEPDQFHAVQEAFKNAGVEEFTVAELTMLAQSEVTLPDDAKEQFEKL IDALEDLEDVQQVYHNVDLGE*" gene 752412..753131 /gene="yeeI" /locus_tag="BSU_06840" /old_locus_tag="BSU06840" downshifts complement(752414) /Source="Nicolas_upshifts" /id="D337" /incds=0 /nref=3 /ntot=70 /MaxReadThrough="1.42969" /MaxDrop="3.99424" /score="-5.23712559" /energy="-7.6" /TU="NA" /idTUdmin="U520" /TUdmin="-5851" /isTUend="FALSE" promotor_-35 752989..752996 /Source="Nicolas_upshift_promotors" /id="U524" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.844155844155844" /psig="0.903096903096903" /xcortree=3101 /SigmaFactorBS="gtttaaaaacgcgggtgtcgaggaatttaCAGTAGCGgagct gacaatgcTTGCGCAAAGTGAAGTAACGcttccggatgatgcaaaggaacagtttgaa a" /listShort="yeeK" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 753010..753029 /Source="Nicolas_upshift_promotors" /id="U524" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.844155844155844" /psig="0.903096903096903" /xcortree=3101 /SigmaFactorBS="gtttaaaaacgcgggtgtcgaggaatttaCAGTAGCGgagct gacaatgcTTGCGCAAAGTGAAGTAACGcttccggatgatgcaaaggaacagtttgaa a" /listShort="yeeK" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 753020 /Source="Nicolas_upshifts" /id="U524" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.844155844155844" /psig="0.903096903096903" /xcortree=3101 /SigmaFactorBS="gtttaaaaacgcgggtgtcgaggaatttaCAGTAGCGgagct gacaatgcTTGCGCAAAGTGAAGTAACGcttccggatgatgcaaaggaacagtttgaa a" /listShort="yeeK" /GFF_Attribute="listLong" downshifts 753113 /Source="Nicolas_upshifts" /id="D338" /incds=0 /nref=223 /ntot=271 /MaxReadThrough="4.94236" /MaxDrop="5.19148" /score="31.0415099" /energy="-11.4" /TU="U523,U524" /idTUdmin="U522" /TUdmin=5 /isTUend="TRUE" promotor_-35 753200..753209 /Source="Nicolas_upshift_promotors" /id="U525" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1279 /SigmaFactorBS="tcccggaaattgttttagctgtatgtaggcggccGCCTATAC GAtctataagatattCTCATACTCTGGACTGTAACctatgtgaaggagagagtaaata t" /listShort="yeeK" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 753223..753242 /Source="Nicolas_upshift_promotors" /id="U525" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1279 /SigmaFactorBS="tcccggaaattgttttagctgtatgtaggcggccGCCTATAC GAtctataagatattCTCATACTCTGGACTGTAACctatgtgaaggagagagtaaata t" /listShort="yeeK" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 753226 /Source="Nicolas_upshifts" /id="U525" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1279 /SigmaFactorBS="tcccggaaattgttttagctgtatgtaggcggccGCCTATAC GAtctataagatattCTCATACTCTGGACTGTAACctatgtgaaggagagagtaaata t" /listShort="yeeK" /GFF_Attribute="listLong" promotor_-10 complement(753230..753248) /Source="Nicolas_upshift_promotors" /id="U526" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.935064935064935" /psig="0.935064935064935" /xcortree=1214 /SigmaFactorBS="aatgaccaaaaccaggtccgccatacatatgtcttgtatcaG TCATAtttactctctccttcACATAGGTTACAGTCCAGAgtatgagaatatcttatag a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(753250) /Source="Nicolas_upshifts" /id="U526" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.935064935064935" /psig="0.935064935064935" /xcortree=1214 /SigmaFactorBS="aatgaccaaaaccaggtccgccatacatatgtcttgtatcaG TCATAtttactctctccttcACATAGGTTACAGTCCAGAgtatgagaatatcttatag a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(753264..753269) /Source="Nicolas_upshift_promotors" /id="U526" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.935064935064935" /psig="0.935064935064935" /xcortree=1214 /SigmaFactorBS="aatgaccaaaaccaggtccgccatacatatgtcttgtatcaG TCATAtttactctctccttcACATAGGTTACAGTCCAGAgtatgagaatatcttatag a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" CDS 753265..753702 /gene="cotK" /locus_tag="BSU_06850" /old_locus_tag="BSU06850" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:10714992, 19060142, 19933362" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10714992, 19060142, 19933362; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="spore inner coat protein" /protein_id="NP_388567.2" /db_xref="EnsemblGenomes-Gn:BSU06850" /db_xref="EnsemblGenomes-Tr:CAB12505" /db_xref="GOA:O31510" /db_xref="SubtiList:BG12825" /db_xref="UniProtKB/Swiss-Prot:O31510" /translation="MTDTRHMYGGPGFGHYQGFGIGHPGYGMQSTGYPGYGMYGGHPG YGMQGYPDHGIHGGVGGYPGYGGYGGYPSGGYGGSPGTGSYPSMHHENDGHHHYYHHH HDGKDNLHHHHHHVGKDNHHHHHDGHYGHHHHHMGHWGKDGYK*" gene 753265..753702 /gene="cotK" /locus_tag="BSU_06850" /old_locus_tag="BSU06850" downshifts complement(753272) /Source="Nicolas_upshifts" /id="D339" /incds=0 /nref=1 /ntot=4 /MaxReadThrough="1.62645" /MaxDrop="3.26146" /score="-5.23712559" /energy="-7.6" /TU="NA" /idTUdmin="U520" /TUdmin="-6709" /isTUend="FALSE" downshifts 753702 /Source="Nicolas_upshifts" /id="D340" /incds=0 /nref=82 /ntot=208 /MaxReadThrough="2.37564" /MaxDrop="8.21113" /score="17.7046271" /energy="-9" /TU="U525" /idTUdmin="U523" /TUdmin=0 /isTUend="TRUE" promotor_-35 753762..753769 /Source="Nicolas_upshift_promotors" /id="U527" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.938061938061938" /psig="0.999000999001" /xcortree=2200 /SigmaFactorBS="cttgcagatcaagagtgtttttttagctttttTCTTGACTgt tcagtctggaaaaTGGTAACATTTGTTTCAGGAggtgatcattttttggggaggaata a" /listShort="yezE" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 753785..753804 /Source="Nicolas_upshift_promotors" /id="U527" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.938061938061938" /psig="0.999000999001" /xcortree=2200 /SigmaFactorBS="cttgcagatcaagagtgtttttttagctttttTCTTGACTgt tcagtctggaaaaTGGTAACATTTGTTTCAGGAggtgatcattttttggggaggaata a" /listShort="yezE" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 753790 /Source="Nicolas_upshifts" /id="U527" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.938061938061938" /psig="0.999000999001" /xcortree=2200 /SigmaFactorBS="cttgcagatcaagagtgtttttttagctttttTCTTGACTgt tcagtctggaaaaTGGTAACATTTGTTTCAGGAggtgatcattttttggggaggaata a" /listShort="yezE" /GFF_Attribute="listLong" CDS 753817..754401 /gene="yezE" /locus_tag="BSU_06860" /old_locus_tag="BSU06860" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative transcriptional regulator (TetR family)" /protein_id="YP_054572.1" /db_xref="EnsemblGenomes-Gn:BSU06860" /db_xref="EnsemblGenomes-Tr:CAE01448" /db_xref="GOA:Q7WY76" /db_xref="InterPro:IPR001647" /db_xref="InterPro:IPR009057" /db_xref="InterPro:IPR036271" /db_xref="SubtiList:BG14194" /db_xref="UniProtKB/Swiss-Prot:Q7WY76" /translation="MGRNKEFDTALVLHRAIEVFGEYGYEGTSLQDLLSHLGIARQSL YDTYGTKRDLFLSAVKSYLEGKNAAVMERLEAPGSVKEAIRDIFQEGVNALRDPERAK ACYIINSAIEQIPHDPELARYFERQSKQLEDAFYHGLLRAKDQGELNGEDTDISALAR YLNQSRLSLTFIAKVTADMDRLQDHVDVSLSVLD*" gene 753817..754401 /gene="yezE" /locus_tag="BSU_06860" /old_locus_tag="BSU06860" downshifts 754382 /Source="Nicolas_upshifts" /id="D341" /incds=0 /nref=26 /ntot=216 /MaxReadThrough="2.43615" /MaxDrop="3.31193" /score="17.7046271" /energy="-9" /TU="NA" /idTUdmin="U527" /TUdmin="-2" /isTUend="TRUE" CDS 754480..754923 /gene="yesE" /locus_tag="BSU_06870" /old_locus_tag="BSU06870" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_388568.1" /db_xref="EnsemblGenomes-Gn:BSU06870" /db_xref="EnsemblGenomes-Tr:CAB12506" /db_xref="InterPro:IPR009959" /db_xref="InterPro:IPR032710" /db_xref="PDB:1S5A" /db_xref="SubtiList:BG12844" /db_xref="UniProtKB/Swiss-Prot:O31511" /translation="MLMNEFEKACETLRKFMAYMLEKDMKSWTELWDENAVFEFPYAP EGSPKRIEGKAAIYDYIKDYPKQIHLSSFTAPTVYRSADSNTVIAEFQCDGHVIETGL PYRQSYISVIETRDGRIVRYRDYWNPLVVKEAFGGSFLQTEESGK*" gene 754480..754923 /gene="yesE" /locus_tag="BSU_06870" /old_locus_tag="BSU06870" CDS 754920..755780 /gene="yesF" /locus_tag="BSU_06880" /old_locus_tag="BSU06880" /EC_number="1.-.-.-" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 21494745; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative oxidoreductase" /protein_id="NP_388569.1" /db_xref="EnsemblGenomes-Gn:BSU06880" /db_xref="EnsemblGenomes-Tr:CAB12507" /db_xref="GOA:O31512" /db_xref="InterPro:IPR001509" /db_xref="InterPro:IPR008030" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG11808" /db_xref="UniProtKB/Swiss-Prot:O31512" /translation="MMKQNPILITGGTGTVGSRIASRLIKLGYRVRIASRKKGALADA EYVYFNWKYASSFTPALEQVKQIYLVAPVGVFDPAPYVLPFLKEAKRLGAKRVVMQSA SVVSENGPVFGALHQAVREFPEWTVLRPSYFMQNFINVQHRMSIQTEGRITTASGEGK LGFIDADDIAETAVRALIDDVPHQTHHILTGPEALSYAEAAEIIGAAAGRRVEHVSIS RSELQHKMEAGGLPADYAHFMAKLDEAISHGAEHRVTDTVKRVTGKEPRSLSEFAAAH AAYWTSFWTE*" gene 754920..755780 /gene="yesF" /locus_tag="BSU_06880" /old_locus_tag="BSU06880" promotor_-35 755842..755847 /Source="Nicolas_upshift_promotors" /id="U528" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp="0.993006993006993" /psig="0.993006993006993" /xcortree=1097 /SigmaFactorBS="ccgaaggtcttcttattgaaaaagctaagtcgtgttttaGTC ATAatcatgcctcctgccTCATACCTATTAAGGTCATtgtttttgagaaaggaggagc c" /listShort="cotJA, cotJB, cotJC, S246, yesJ, yesK" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 755863..755881 /Source="Nicolas_upshift_promotors" /id="U528" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp="0.993006993006993" /psig="0.993006993006993" /xcortree=1097 /SigmaFactorBS="ccgaaggtcttcttattgaaaaagctaagtcgtgttttaGTC ATAatcatgcctcctgccTCATACCTATTAAGGTCATtgtttttgagaaaggaggagc c" /listShort="cotJA, cotJB, cotJC, S246, yesJ, yesK" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 755863 /Source="Nicolas_upshifts" /id="U528" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp="0.993006993006993" /psig="0.993006993006993" /xcortree=1097 /SigmaFactorBS="ccgaaggtcttcttattgaaaaagctaagtcgtgttttaGTC ATAatcatgcctcctgccTCATACCTATTAAGGTCATtgtttttgagaaaggaggagc c" /listShort="cotJA, cotJB, cotJC, S246, yesJ, yesK" /GFF_Attribute="listLong" promotor_-10 complement(755885..755899) /Source="Nicolas_upshift_promotors" /id="U529" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp=1 /psig=0 /xcortree=707 /SigmaFactorBS="ggcgtatatgatttgacaggcgtaaacggctgcatatccTTC ATtccggctCCTCCTTTCTCAAAAacaatgaccttaataggtatgaggcaggaggcat g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(755890) /Source="Nicolas_upshifts" /id="U529" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp=1 /psig=0 /xcortree=707 /SigmaFactorBS="ggcgtatatgatttgacaggcgtaaacggctgcatatccTTC ATtccggctCCTCCTTTCTCAAAAacaatgaccttaataggtatgaggcaggaggcat g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(755907..755911) /Source="Nicolas_upshift_promotors" /id="U529" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp=1 /psig=0 /xcortree=707 /SigmaFactorBS="ggcgtatatgatttgacaggcgtaaacggctgcatatccTTC ATtccggctCCTCCTTTCTCAAAAacaatgaccttaataggtatgaggcaggaggcat g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" CDS 755907..756155 /gene="cotJA" /locus_tag="BSU_06890" /old_locus_tag="BSU06890" /function="16.5: Explore" /function="16.13: Shape" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:9364920" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9364920; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="component of the inner spore coat" /protein_id="NP_388570.1" /db_xref="EnsemblGenomes-Gn:BSU06890" /db_xref="EnsemblGenomes-Tr:CAB12508" /db_xref="InterPro:IPR020256" /db_xref="SubtiList:BG11799" /db_xref="UniProtKB/Swiss-Prot:Q45536" /translation="MKDMQPFTPVKSYTPFHSRFDPCPPIGKKYYRTPPNLYMTFQPE HMEQFSPMEALRKGTLWKDLYDFYENPYRGGDAHGKKG*" gene 755907..756155 /gene="cotJA" /locus_tag="BSU_06890" /old_locus_tag="BSU06890" CDS 756139..756402 /gene="cotJB" /locus_tag="BSU_06900" /old_locus_tag="BSU06900" /function="16.13: Shape" /function="16.8: Protect" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:9364920" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9364920; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="component of the inner spore coat" /protein_id="NP_388571.2" /db_xref="EnsemblGenomes-Gn:BSU06900" /db_xref="EnsemblGenomes-Tr:CAB12509" /db_xref="InterPro:IPR016571" /db_xref="InterPro:IPR024207" /db_xref="SubtiList:BG11800" /db_xref="UniProtKB/Swiss-Prot:Q45537" /translation="MAKKVDAEYYRQLEQIQAADFVLVELSLYLNTHPHDEDALKQFN QYSGYSRHLKRQFESSYGPLLQFGNSPAGKDWDWGKGPWPWQV*" gene 756139..756402 /gene="cotJB" /locus_tag="BSU_06900" /old_locus_tag="BSU06900" CDS 756417..756986 /gene="cotJC" /locus_tag="BSU_06910" /old_locus_tag="BSU06910" /EC_number="1.11.1.6" /function="16.8: Protect" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:7768848, 9364920" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7768848, 9364920; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="enzyme component of the inner spore coat" /protein_id="NP_388572.1" /db_xref="EnsemblGenomes-Gn:BSU06910" /db_xref="EnsemblGenomes-Tr:CAB12510" /db_xref="InterPro:IPR007760" /db_xref="InterPro:IPR009078" /db_xref="InterPro:IPR012347" /db_xref="SubtiList:BG11801" /db_xref="UniProtKB/Swiss-Prot:Q45538" /translation="MWVYEKKLQYPVKVSTCNPTLAKYLIEQYGGADGELAAALRYLN QRYTIPDKVIGLLTDIGTEEFAHLEMIATMVYKLTKDATPEQLREAGLGDHYVNHDSA LFYHNAAGVPFTASYIQAKGDPIADLYEDIAAEEKARATYQWLIDISDDPDLNDSLRF LREREIVHSMRFREAVEILKEERDKKKIF*" gene 756417..756986 /gene="cotJC" /locus_tag="BSU_06910" /old_locus_tag="BSU06910" S_feature 756987..757065 /Source="Nicolas_S_feature" /locus_tag="new_756987_757065" /HighExp="S4, S5, S3, S7, S6, B36, LoTm, BT, T5.0H, S8" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigEF" /TUshortPSig="0.993" /TUlongSig="NA" /TUlongPSig="NA" /label="S246" promotor_-35 757038..757043 /Source="Nicolas_upshift_promotors" /id="U530" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.518481518481518" /psig="0.999000999001" /xcortree=3085 /SigmaFactorBS="tcatacacccttttacatacagagaaaatggTCTGTTtttgc agtttggtcTGCATTATAATCAAGGTGTGtgtgcaagcttactttttgattgggaggc c" /listShort="yesJ" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 757058..757077 /Source="Nicolas_upshift_promotors" /id="U530" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.518481518481518" /psig="0.999000999001" /xcortree=3085 /SigmaFactorBS="tcatacacccttttacatacagagaaaatggTCTGTTtttgc agtttggtcTGCATTATAATCAAGGTGTGtgtgcaagcttactttttgattgggaggc c" /listShort="yesJ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 757067 /Source="Nicolas_upshifts" /id="U530" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.518481518481518" /psig="0.999000999001" /xcortree=3085 /SigmaFactorBS="tcatacacccttttacatacagagaaaatggTCTGTTtttgc agtttggtcTGCATTATAATCAAGGTGTGtgtgcaagcttactttttgattgggaggc c" /listShort="yesJ" /GFF_Attribute="listLong" CDS 757111..757653 /gene="yesJ" /locus_tag="BSU_06920" /old_locus_tag="BSU06920" /EC_number="2.3.1.-" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative acetyltransferase" /protein_id="NP_388573.1" /db_xref="EnsemblGenomes-Gn:BSU06920" /db_xref="EnsemblGenomes-Tr:CAB12511" /db_xref="GOA:O31513" /db_xref="InterPro:IPR000182" /db_xref="InterPro:IPR016181" /db_xref="SubtiList:BG11809" /db_xref="UniProtKB/Swiss-Prot:O31513" /translation="MTAFKIENETIADGFYACPAVYEDAESITGLLVRTAEWLRDRGS NQWSGLLKGQDIHDITGSIEKGHVFVFKKDEELAAVVMLLPAPSEWDRTLWGDDGHEE SIYLHRLAVSRRFAGQGLGARVLQWAETGIHFPEKTRIRLDCVADSDALHSFYRRMGY EFMGADASGYHLFEKEITAE*" gene 757111..757653 /gene="yesJ" /locus_tag="BSU_06920" /old_locus_tag="BSU06920" downshifts 757620 /Source="Nicolas_upshifts" /id="D342" /incds=0 /nref=104 /ntot=251 /MaxReadThrough="3.04389" /MaxDrop="4.5316" /score="8.56782582" /energy="-5.8" /TU="U528" /idTUdmin="U530" /TUdmin=2 /isTUend="TRUE" CDS 757676..757978 /gene="yesK" /locus_tag="BSU_06930" /old_locus_tag="BSU06930" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative membrane component" /protein_id="NP_388574.2" /db_xref="EnsemblGenomes-Gn:BSU06930" /db_xref="EnsemblGenomes-Tr:CAB12512" /db_xref="GOA:O31514" /db_xref="InterPro:IPR025434" /db_xref="SubtiList:BG12845" /db_xref="UniProtKB/Swiss-Prot:O31514" /translation="MSFSKREAGDVWSILFVTGIVTACLFAGVSVLMRMRFPDKSRPE WMLAGLIVLGVFAIWYSLVYVRGWEGAALGMLGFNVIFGAIAGYLIDKAIRRYRKR*" gene 757676..757978 /gene="yesK" /locus_tag="BSU_06930" /old_locus_tag="BSU06930" promotor_-35 758021..758029 /Source="Nicolas_upshift_promotors" /id="U531" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.895104895104895" /psig="0.895104895104895" /xcortree=362 /SigmaFactorBS="gccgtctctcaacaggtcgaaattttcacagaccgGCAGGAA TTttctttcgaaAGGAGAAATACATATTACTttaaaatgaaagcgttttccaaagcag g" /listShort="yesL, yesM" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 758040..758058 /Source="Nicolas_upshift_promotors" /id="U531" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.895104895104895" /psig="0.895104895104895" /xcortree=362 /SigmaFactorBS="gccgtctctcaacaggtcgaaattttcacagaccgGCAGGAA TTttctttcgaaAGGAGAAATACATATTACTttaaaatgaaagcgttttccaaagcag g" /listShort="yesL, yesM" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 758046 /Source="Nicolas_upshifts" /id="U531" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.895104895104895" /psig="0.895104895104895" /xcortree=362 /SigmaFactorBS="gccgtctctcaacaggtcgaaattttcacagaccgGCAGGAA TTttctttcgaaAGGAGAAATACATATTACTttaaaatgaaagcgttttccaaagcag g" /listShort="yesL, yesM" /GFF_Attribute="listLong" CDS 758093..758722 /gene="yesL" /locus_tag="BSU_06940" /old_locus_tag="BSU06940" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406, 25441682; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative permease or sensor of a three componentsystem for pectin and rhamnogalacturonan transport anddegradation" /protein_id="NP_388575.1" /db_xref="EnsemblGenomes-Gn:BSU06940" /db_xref="EnsemblGenomes-Tr:CAB12513" /db_xref="GOA:O31515" /db_xref="InterPro:IPR006938" /db_xref="SubtiList:BG12846" /db_xref="UniProtKB/Swiss-Prot:O31515" /translation="MLMIHSVANGLNHFCTWVMRLAYLNVLWILFSLAGLVVFGLMPA TAAMFTVAREWAKGNTDAPVFSVFFRTFKKEWRASQILGLIVVTAALFLFADMRIAAQ MDQPVLVNVFVSISLIFAFVVLYVFPVFSHFDVKIREVLSISFFIAFSRPAVTLLMAA GAVGVLCLVLFHVTFLLFFSGSLLSLILTKLSFKAFRSMDQRQEKEKAA*" gene 758093..758722 /gene="yesL" /locus_tag="BSU_06940" /old_locus_tag="BSU06940" CDS 758719..760452 /gene="yesM" /locus_tag="BSU_06950" /old_locus_tag="BSU06950" /function="16.3: Control" /function="16.12: Sense" /experiment="publication(s) with functional evidences, PMID:11717295, 23436677, 25441682" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11717295, 23436677, 25441682; Product type rc: receptor" /codon_start=1 /transl_table=11 /product="two-component sensor histidine kinase [YesN]" /protein_id="NP_388576.1" /db_xref="EnsemblGenomes-Gn:BSU06950" /db_xref="EnsemblGenomes-Tr:CAB12514" /db_xref="GOA:O31516" /db_xref="InterPro:IPR003594" /db_xref="InterPro:IPR003660" /db_xref="InterPro:IPR004358" /db_xref="InterPro:IPR005467" /db_xref="InterPro:IPR010559" /db_xref="InterPro:IPR033479" /db_xref="InterPro:IPR036890" /db_xref="SubtiList:BG12847" /db_xref="UniProtKB/Swiss-Prot:O31516" /translation="MKKRVAGWYRRMKIKDKLFVFLSLIMAVSFLFVYSGVQYAFHVY DEQIYRKSSEVLRMSSERIEDELKKIEDVSYEIITDEQIQRILSMQNRDDTYDQYQMK QELWDQLAGYASDEKYIDSIHVIDARGSEYSAGSSSSDLLQQEQEEVFKRAKAKSGRN LWMTLGGSDPVLISARQIRSYHQLSLNGLGMVLIQVNVKQMIRDVPKDWGDSVGDIMI ADQGGNLVYTAHASAHVPEAAKETLKHPGYDLIKKNGKRYFISYLQSSYQNWSYYNVI PFDQMFAKISFMKTVIGTCFLLFFCVVLLFGRKIANSITEPIEQLVTAMKSVQHSGIE AGVSLSLPEHTQDEAGMLNRHFTVMMKRINELMEENVEKQLIIKETELKALQAQINPH FLYNTLESINWLAKANQQKQISKMVESLGFLLRNSIHMKKDIVTIQEEADIVRHYMTI QRFRFEERLKFTLDIDDEVKHCLIPKLTLQPLAENAIQYALEPFTRPCAIRIQAKKAK GCVCITVEDNGPGMDGRILESTGGRGIGLWNIRERISLTFGEPYGLRIHSEHEKGTRI VITIPCRNEVV*" gene 758719..760452 /gene="yesM" /locus_tag="BSU_06950" /old_locus_tag="BSU06950" CDS 760452..761558 /gene="yesN" /locus_tag="BSU_06960" /old_locus_tag="BSU06960" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:25441682" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 25441682; Product type r: regulator" /codon_start=1 /transl_table=11 /product="two-component response regulator [YesM]" /protein_id="NP_388577.1" /db_xref="EnsemblGenomes-Gn:BSU06960" /db_xref="EnsemblGenomes-Tr:CAB12515" /db_xref="GOA:O31517" /db_xref="InterPro:IPR001789" /db_xref="InterPro:IPR009057" /db_xref="InterPro:IPR011006" /db_xref="InterPro:IPR018060" /db_xref="SubtiList:BG12848" /db_xref="UniProtKB/Swiss-Prot:O31517" /translation="MYKILLADDERIILDGMAGIIEWESLGASLIGKAQNGHEAYEKI VHKQPHIVITDVKMPGMDGLELIKKVSAVSPSVQFIVLSGFGEFEYAKEAMKYGVKHY LLKPCNEQQIISSLEEIIAELKRQDVHKKKTAHLKHELDHIRSFAADQYLEGLIAGVA QLSPPPSLAGKKIRLLILKGEQSIDAAAREALGSALTAVCSSGEWTVLAVEENAAEKV AEVFADRKMAISQAGELRHAGQLFRDTAEASGDLHGSAVISKMIRLIADELGNPNLSL KWAAKDMLFMNPDYLGKLFKQETGEKFSQYVTRVRLEHAMKQMKIRRDVSVSEIAEEI GFGDNPKYFSLVFKKYTGLTPSEFRRKQGGASAG*" gene 760452..761558 /gene="yesN" /locus_tag="BSU_06960" /old_locus_tag="BSU06960" downshifts 761512 /Source="Nicolas_upshifts" /id="D343" /incds=0 /nref=4 /ntot=43 /MaxReadThrough="0.271749999999999" /MaxDrop="3.41261" /score="3.12085441" /energy="-10.3" /TU="NA" /idTUdmin="U531" /TUdmin=1408 /isTUend="FALSE" promotor_-35 761597..761600 /Source="Nicolas_upshift_promotors" /id="U532" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.882117882117882" /psig="0.992007992007992" /xcortree=356 /SigmaFactorBS="tctctgtttttttgactttcgccactgttttttgaGTGTttc gccctatccgaACGCTTTAAAATAAAATGTAagcacttacattaaaggggggattggt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 761615..761634 /Source="Nicolas_upshift_promotors" /id="U532" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.882117882117882" /psig="0.992007992007992" /xcortree=356 /SigmaFactorBS="tctctgtttttttgactttcgccactgttttttgaGTGTttc gccctatccgaACGCTTTAAAATAAAATGTAagcacttacattaaaggggggattggt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 761622 /Source="Nicolas_upshifts" /id="U532" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.882117882117882" /psig="0.992007992007992" /xcortree=356 /SigmaFactorBS="tctctgtttttttgactttcgccactgttttttgaGTGTttc gccctatccgaACGCTTTAAAATAAAATGTAagcacttacattaaaggggggattggt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" CDS 761662..762945 /gene="yesO" /locus_tag="BSU_06970" /old_locus_tag="BSU06970" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:16781735, 17449691, 25658435" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16781735, 17449691, 25658435; Product type lp: lipoprotein" /codon_start=1 /transl_table=11 /product="pectin degradation byproducts (rhamnose oligosaccharides)-binding lipoprotein" /protein_id="NP_388578.2" /db_xref="EnsemblGenomes-Gn:BSU06970" /db_xref="EnsemblGenomes-Tr:CAB12516" /db_xref="PDB:4R6K" /db_xref="SubtiList:BG12849" /db_xref="UniProtKB/Swiss-Prot:O31518" /translation="MKKICYVLLSLVCVFLFSGCSAGEEASGKKEDVTLRIAWWGGQP RHDYTTKVIELYEKKNPHVHIEAEFANWDDYWKKLAPMSAAGQLPDVIQMDTAYLAQY GKKNQLEDLTPYTKDGTIDVSSIDENMLSGGKIDNKLYGFTLGVNVLSVIANEDLLKK AGVSINQENWTWEDYEKLAYDLQEKAGVYGSNGMHPPDIFFPYYLRTKGERFYKEDGT GLAYQDDQLFVDYFERQLRLVKAKTSPTPDESAQIKGMEDDFIVKGKSAITWNYSNQY LGFARLTDSPLSLYLPPEQMQEKALTLKPSMLFSIPKSSEHKKEAAKFINFFVNNEEA NQLIKGERGVPVSDKVADAIKPKLNEEETNIVEYVETASKNISKADPPEPVGSAEVIK LLKDTSDQILYQKVSPEKAAKTFRKKANEILERNN*" gene 761662..762945 /gene="yesO" /locus_tag="BSU_06970" /old_locus_tag="BSU06970" CDS 762942..763871 /gene="rhgP" /locus_tag="BSU_06980" /old_locus_tag="BSU06980" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:15849754, 16850406, 17449691" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15849754, 16850406, 17449691; Product type t: transporter" /codon_start=1 /transl_table=11 /product="rhamnogalacturonan permease" /protein_id="NP_388579.1" /db_xref="EnsemblGenomes-Gn:BSU06980" /db_xref="EnsemblGenomes-Tr:CAB12517" /db_xref="GOA:O31519" /db_xref="InterPro:IPR000515" /db_xref="InterPro:IPR035906" /db_xref="SubtiList:BG12850" /db_xref="UniProtKB/Swiss-Prot:O31519" /translation="MTGNGADAMKKSRSIRKDNLAGYAFISPFIIGFLCFTVIPMGAS LFLSFTSYDLFTAPKWIGLDNFKEMFTGDEKYWQSLKVTFTYVLAGVPLRLGFALFIA VILNNAAKGTAIYRTLFYLPSIIGGSVAVAIMWRNIFGNDGVINALLFFVGIDQKILW YQNPTSALWTLILLSVWQFGSSMLIFLAGLKNIPSSYLEAASVDGANRVQRFFKITLP ILTPIIFFNLVMQTISAFMTFTPAYIISKGEGGPLDGTLLYSLYLFQRAFNYFQMGYA SAMAWVMLVIVGLITLILFKTSSYWVHYESKEE*" gene 762942..763871 /gene="rhgP" /locus_tag="BSU_06980" /old_locus_tag="BSU06980" CDS 763875..764765 /gene="rhgQ" /locus_tag="BSU_06990" /old_locus_tag="BSU06990" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:15849754, 16850406, 17449691" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15849754, 16850406, 17449691; Product type t: transporter" /codon_start=1 /transl_table=11 /product="rhamnogalacturonan permease" /protein_id="NP_388580.1" /db_xref="EnsemblGenomes-Gn:BSU06990" /db_xref="EnsemblGenomes-Tr:CAB12518" /db_xref="GOA:O31520" /db_xref="InterPro:IPR000515" /db_xref="InterPro:IPR035906" /db_xref="SubtiList:BG12851" /db_xref="UniProtKB/Swiss-Prot:O31520" /translation="MEPVNQPVREAPVFERKKAGRVSPKRILFHVFTATLAVLLLYPV IWLFVSSFKESASIFTTSHSLIPDPFILSNYAEGWKGIAGQPFLTFIKNSAIIVGLST IGAVMSSAVIAYGFARIPFKGKKFWFACMMGTLMLPHEVLMIPQYIMFAKLDWLNSFK PIVVPQFFGHAFFIFLMIQFIRTIPEELDEAARIDGCGRFACFWRIILPLIAPALATS AIFSFYWKWEELIQPLLYLNKPELYPVSLALKLFLDTESASNWGAMFAMSAVSLLPVI LVFFLFQKYIVQGISTTGLK*" gene 763875..764765 /gene="rhgQ" /locus_tag="BSU_06990" /old_locus_tag="BSU06990" CDS 764781..765815 /gene="rhgH" /locus_tag="BSU_07000" /old_locus_tag="BSU07000" /EC_number="3.2.1.172" /function="16.6: Maintain" /function="16.13: Shape" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1b: Function from experimental evidences in the studied species; PubMedId: 16781735, 17449691; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="rhamnogalacturonan hydrolase" /protein_id="NP_388581.1" /db_xref="EnsemblGenomes-Gn:BSU07000" /db_xref="EnsemblGenomes-Tr:CAB12519" /db_xref="GOA:O31521" /db_xref="InterPro:IPR008928" /db_xref="InterPro:IPR010905" /db_xref="SubtiList:BG12852" /db_xref="UniProtKB/Swiss-Prot:O31521" /translation="MAQLIFDEEKVTSVIDRIVKRTFQMDFAWDWPGGVAFYGVAEAY EATENEEYINLLKTWVDEQLEDGLPPLSINGVSIGHTLLFLHKVTGDDVYLETAAEMA EYVLHKAPRFGEGILQHTVNAAEYVFPEQAWADTLMMAGLFMLRIGRVMEREDYFEDG LRQFHGHEDVLQDPVTNLYYHAWDNKAQNHLSGIYWGRANGWAALTMAKALPLIEVTH PSFMIIDGSLRDQLSALVRLQDESGLWHTILDDPDSYLEVSASAGIASALMSSGKLYT KYVQKSLAAILDAVEEDGRVSRVSAGTAVMKNAEGYKQVPYKRIQGWGQGLALTFLAD VLKTKKRLYQ*" gene 764781..765815 /gene="rhgH" /locus_tag="BSU_07000" /old_locus_tag="BSU07000" CDS 765838..768123 /gene="rhgR" /locus_tag="BSU_07010" /old_locus_tag="BSU07010" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:16781735, 17449691, 19651770" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16781735, 17449691, 19651770; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator (AraC/XylS family)" /protein_id="NP_388582.1" /db_xref="EnsemblGenomes-Gn:BSU07010" /db_xref="EnsemblGenomes-Tr:CAB12520" /db_xref="GOA:O31522" /db_xref="InterPro:IPR009057" /db_xref="InterPro:IPR014710" /db_xref="InterPro:IPR018060" /db_xref="InterPro:IPR018062" /db_xref="SubtiList:BG12853" /db_xref="UniProtKB/Swiss-Prot:O31522" /translation="MKKQPQQKERVSRWKGTYFKRNFVFILLIACIPGLLTGGAIYFL SIDKVEKELQRSHETQVAREVSRMDEKLGVLELALTQMAYDSSLMNGLAERDLEKDFT FSYQLTKKLFLLRDQQPLIEQASIFLNSPRPLVLSPEYSALTEQEALRKYRSLLASDH SIYWKRSGNQAMLIQLIPGAAEKPFGAIMLAVDPKEMESILQSLSPYPDGSALLLDQN REVLFHEGEKDFEKTLLHEIKKQPAENGHFQMEWKGKVYSVSFGEMNRMHQQWTFVSA APLSAITAPMVFLSKVIIVMLVICIGLAVCMTWYASKKIYRPIQHLLGLFTGGEKKTW QASGQDEFKWIEKRWQDLSLESRKLQQQLLRQTPHMKKSFLQHLLQSDFYYDNEESLR FRMEEAGWNIGGNVFHVLDLQVTGLRCEKSIFREGDEQLAVFTLTNIAEELAAKRVFQ LSILDIGRLSVTVLVMKTNSSDLKAYITELARQFGDVTGLCLTSTLSSKTERVTEIPS LFQDVKCGKSRRKFANRDQVIDLQADFPRDEQFAPYYPFELEKQIVQTIRLERKQEAK ELIDGCMKELSEKAAIDRHVHSALIQLFSRIQEDILHSGLNPSELFQHRNPFLDISEL REPNEAAAWLMDVVVTPYLSKLEGRKNRQQKQLAERVIAMIHEQYMADISLESCADAL GMNSYTLSKAFKQVTGINFIDYVTQIRIEKAKELLVNTNKKIHDVSEEVGYRHNYFNR IFKKQVGMPPGVFRQMYQETP*" gene 765838..768123 /gene="rhgR" /locus_tag="BSU_07010" /old_locus_tag="BSU07010" CDS 768137..768835 /gene="rhgT" /locus_tag="BSU_07020" /old_locus_tag="BSU07020" /EC_number="3.1.1.-" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:16781735, 17449691, 17957779" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16781735, 17449691, 17957779; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="rhamnogalacturonan acetylesterase" /protein_id="NP_388583.1" /db_xref="EnsemblGenomes-Gn:BSU07020" /db_xref="EnsemblGenomes-Tr:CAB12521" /db_xref="GOA:O31523" /db_xref="InterPro:IPR013830" /db_xref="InterPro:IPR036514" /db_xref="SubtiList:BG12854" /db_xref="UniProtKB/Swiss-Prot:O31523" /translation="MMKKPIQVFLAGDSTVSDCPPHEAPMAGWGQVFGQLFSEGVLVR NHAKGGASTNSFVEEGRLQAIAEHITQGDYLLIQFGHNDQKPRGTKPYSTFQQFLTLF ADTAREKGAHPVFVTSVQRRRFDENGRIEHTLGEYPDAMKALAKELDVPVIDLLAKTK VLYEAYGPEESKRLFVWFQPNEHPNYPDGIEDNTHFSEKGAMEVAKLVAEGIEELGLP LKDHLVSREGKEHV*" gene 768137..768835 /gene="rhgT" /locus_tag="BSU_07020" /old_locus_tag="BSU07020" CDS 768828..769490 /gene="yesU" /locus_tag="BSU_07030" /old_locus_tag="BSU07030" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 16781735, 17449691; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative enzyme" /protein_id="NP_388584.1" /db_xref="EnsemblGenomes-Gn:BSU07030" /db_xref="EnsemblGenomes-Tr:CAB12522" /db_xref="InterPro:IPR013320" /db_xref="InterPro:IPR015305" /db_xref="PDB:1OQ1" /db_xref="SubtiList:BG12855" /db_xref="UniProtKB/Swiss-Prot:O31524" /translation="MYKEGACLYRNPLRSKSDVKDWRMEGGGQISFDDHSLHLSHVQD EAHFVFWCPETFPDGIIVTWDFSPIEQPGLCMLFFAAAGIRGEDLFDPSLRKRTGTYP EYHSGDINALHLSYFRRKYAEERAFRTCNLRKSRGFHLAAMGADPLPSPDDADSPYRM KLIKDKGYVHFSINGLPILEWMDDGSTYGPVLTKGKIGFRQMAPMKAVYRDFAVHQAV RR*" gene 768828..769490 /gene="yesU" /locus_tag="BSU_07030" /old_locus_tag="BSU07030" CDS 769487..770113 /gene="yesV" /locus_tag="BSU_07040" /old_locus_tag="BSU07040" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406, 17449691; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative integral inner membrane component" /protein_id="NP_388585.1" /db_xref="EnsemblGenomes-Gn:BSU07040" /db_xref="EnsemblGenomes-Tr:CAB12523" /db_xref="InterPro:IPR006938" /db_xref="SubtiList:BG12856" /db_xref="UniProtKB/Swiss-Prot:O31525" /translation="MKTTVTDALYAGCEAVVKIAWLNGLWLLFTLLGGVLFGWAPSTA AMCAVIRKWLMGQKDVPIFSLFLDTYKKEFLKVNAIGLAFSALLLILSANYHYFSAST NWLSFAVTSCTLLAGLLYIIALMYVFPLYVHYQLPLRKYIPQALLFGAMRPLTTGCML IGCGFVLYLLYTLPGLIPFYGPCLFGLVLMFFALRGFQKTEAQHHQAG*" gene 769487..770113 /gene="yesV" /locus_tag="BSU_07040" /old_locus_tag="BSU07040" CDS 770234..772096 /gene="rhgW" /locus_tag="BSU_07050" /old_locus_tag="BSU07050" /EC_number="4.2.2.23" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:16781735, 17449691, 19193638" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16781735, 17449691, 19193638; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="rhamnogalacturonan endolyase" /protein_id="NP_388586.1" /db_xref="EnsemblGenomes-Gn:BSU07050" /db_xref="EnsemblGenomes-Tr:CAB12524" /db_xref="GOA:O31526" /db_xref="InterPro:IPR013783" /db_xref="InterPro:IPR034641" /db_xref="PDB:2Z8R" /db_xref="PDB:2Z8S" /db_xref="PDB:2ZUX" /db_xref="SubtiList:BG12857" /db_xref="UniProtKB/Swiss-Prot:O31526" /translation="MRRSCLMIRRRKRMFTAVTLLVLLVMGTSVCPVKAEGAARQMEA LNRGLVAVKTDGGIFVSWRFLGTENASVLFNVYRDGQKLNAAPVKTTNYVDKNGSAGS TYTVRAVVNGTEQPASEKASVWAQPYHSVPLDKPAGGTTPKGESYTYSANDASVGDVD GDGQYELILKWDPSNSKDNSQDGYTGDVLIDAYKLDGTKLWRINLGKNIRAGAHYTQF MVYDLDGDGKAEVAMKTADGTKDGTGKVIGNANADYRNEQGRVLSGPEYLTVFQGSTG KELVTANFEPARGNVSDWGDSYGNRVDRFLAGIAYLDGQRPSLIMTRGYYAKTMLVAY NFRDGKLSKLWTLDSSKSGNEAFAGQGNHNLSIADVDGDGKDEIIFGSMAVDHDGKGM YSTGLGHGDALHTGDLDPGRPGLEVFQVHEDKNAKYGLSFRDAATGKILWGVYAGKDV GRGMAADIDPRYPGQEVWANGSLYSAKGVKIGSGVPSSTNFGIWWDGDLLREQLDSNR IDKWDYQNGVSKNMLTASGAAANNGTKATPTLQADLLGDWREEVVWRTEDSSALRIYT TTIPTEHRLYTLMHDPVYRLGIAWQNIAYNQPPHTSFFLGDGMAEQPKPNMYTP*" gene 770234..772096 /gene="rhgW" /locus_tag="BSU_07050" /old_locus_tag="BSU07050" promotor_no_box 770274..770374 /Source="Nicolas_upshift_promotors" /id="U533" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.59040959040959" /psig="0.000999000999001" /xcortree=1487 /SigmaFactorBS="tgtttaccgctgttacgttgctggtcttgttggtgatgggaa cctctgtatgtcctgtgaaagctgaaggggcagcgcggcagatggaagcgctgaaccg g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_no_box" upshifts 770334 /Source="Nicolas_upshifts" /id="U533" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.59040959040959" /psig="0.000999000999001" /xcortree=1487 /SigmaFactorBS="tgtttaccgctgttacgttgctggtcttgttggtgatgggaa cctctgtatgtcctgtgaaagctgaaggggcagcgcggcagatggaagcgctgaaccg g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" upshifts complement(770872) /Source="Nicolas_upshifts" /id="U534" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.995004995004995" /psig="0.995004995004995" /xcortree=1380 /SigmaFactorBS="cattgccacttctgctttTCCGTCACCAtcaaggtcatacAC CATAAACTGGGTGTAGTGcgcgcccgctctgatgtttttgccgagattgatccgccat a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 complement(770873..770892) /Source="Nicolas_upshift_promotors" /id="U534" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.995004995004995" /psig="0.995004995004995" /xcortree=1380 /SigmaFactorBS="cattgccacttctgctttTCCGTCACCAtcaaggtcatacAC CATAAACTGGGTGTAGTGcgcgcccgctctgatgtttttgccgagattgatccgccat a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 complement(770905..770914) /Source="Nicolas_upshift_promotors" /id="U534" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.995004995004995" /psig="0.995004995004995" /xcortree=1380 /SigmaFactorBS="cattgccacttctgctttTCCGTCACCAtcaaggtcatacAC CATAAACTGGGTGTAGTGcgcgcccgctctgatgtttttgccgagattgatccgccat a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" CDS 772142..773980 /gene="rhgX" /locus_tag="BSU_07060" /old_locus_tag="BSU07060" /EC_number="4.2.2.24" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:16781735, 17449691, 19193638" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16781735, 17449691, 19193638; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="rhamnogalacturonan exolyase" /protein_id="NP_388587.1" /db_xref="EnsemblGenomes-Gn:BSU07060" /db_xref="EnsemblGenomes-Tr:CAB12525" /db_xref="GOA:O31527" /db_xref="InterPro:IPR013517" /db_xref="InterPro:IPR013783" /db_xref="InterPro:IPR034641" /db_xref="PDB:2ZUY" /db_xref="SubtiList:BG12858" /db_xref="UniProtKB/Swiss-Prot:O31527" /translation="MKPKKRQMEYLTRGLIAVQTEQGVFVSWRFLGTDHETTAFHLYR DGKRITRDPIAESTNFLDQNGTADSVYQVAAVNKGREEKLSKKARVWQENVLEVPLAK PEGGVTPDGKPYTYSANDASVGDIDGDGEYEMILKWDPSNSKDNAHDGYTGEVLIDAY KLDGTFLWRINLGRNIRAGAHYTQFMVYDLDGDGKAEIAMKTADGTTDGKGHIIGDEQ ADFRNEQGRILSGPEYLTVFKGETGEALTTVEYEPPRGKLEDWGDGYGNRMDRFLAGT AYLDGERPSLVMARGYYTRTVLVAYDFRNGRLKKRWVFDSNQPGHEAYAGQGNHSLSV ADVDGDGKDEIIYGAMAVDHDGTGLYSTGLGHGDAMHVGDLDPSRKGLEVFQVHEDAT KPYGLSLRDAGTGEILWGVHAGTDVGRGMAAHIDPSYKGSLVWGIDPPGNDGMSYGLF TSKGEKISDKAPSSANFAIWWDGDLVRELLDHDWDGTIGRPKIEKWDAENGCLKTIFQ PAGVLSNNGTKGNPVLQANLFGDWREEVIWRTEDSSALRIYTTTHLTRHCFYTLMHDP VYRLGIAWQNTAYNQPPHTSFYLGTGMKKPPKPALYIAGSKAEAPL*" gene 772142..773980 /gene="rhgX" /locus_tag="BSU_07060" /old_locus_tag="BSU07060" CDS 774138..774791 /gene="yesY" /locus_tag="BSU_07070" /old_locus_tag="BSU07070" /EC_number="3.1.1.-" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:16781735, 17449691" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16781735, 17449691; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="rhamnogalacturonan acetylesterase" /protein_id="NP_388588.1" /db_xref="EnsemblGenomes-Gn:BSU07070" /db_xref="EnsemblGenomes-Tr:CAB12526" /db_xref="GOA:O31528" /db_xref="InterPro:IPR013830" /db_xref="InterPro:IPR036514" /db_xref="SubtiList:BG12859" /db_xref="UniProtKB/Swiss-Prot:O31528" /translation="MANHIYLAGDSTVQTYGDSTNQGGWGQFLGSHLPEHIQVINRAI GGRSSKTFVEEGRLQAILDVIEPDDWLFVQMGHNDASKNKPERYTEPYTTYKQYLKQY IAGAREKGAHPLLITPVARFHYENGVFLNDFPDYCIAMKQTAAEENVQLIDLMEKSLA FFTEKGEEKVYTYFMISEGINDYTHFTKKGANEMAKLVAKGIKELGLPLTESIIKER* " gene 774138..774791 /gene="yesY" /locus_tag="BSU_07070" /old_locus_tag="BSU07070" CDS 774799..776790 /gene="rhgZ" /locus_tag="BSU_07080" /old_locus_tag="BSU07080" /EC_number="3.2.1.67" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:16781735, 17056685, 17449691, 17485082" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16781735, 17056685, 17449691, 17485082; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="beta-galacturonidase" /protein_id="NP_388589.1" /db_xref="EnsemblGenomes-Gn:BSU07080" /db_xref="EnsemblGenomes-Tr:CAB12527" /db_xref="GOA:O31529" /db_xref="InterPro:IPR003476" /db_xref="InterPro:IPR013529" /db_xref="InterPro:IPR013738" /db_xref="InterPro:IPR013739" /db_xref="InterPro:IPR017853" /db_xref="InterPro:IPR029062" /db_xref="SubtiList:BG12860" /db_xref="UniProtKB/Swiss-Prot:O31529" /translation="MRKLYHGACYYPELWDEETIQQDIDIMREVGVNVVRIGEFAWSV MEPEEGKIDVGFFKEIIARLYDSGIETIMCTPTPTPPIWFSHGRPERMHANEKREIMG HGSRQHACTNNPYFRKKAAIITTAIAKELGRLPGLIGWQLDNEFKCHVAECMCETCLR LWHDWLKNRYGVIERLNEAWGTDVWSETYQTFEQVPQPGPAPFLHHASLRTMYQLFSM EMIASFADEQAKIIRCYSDAPITHNGSVMFSVDNERMFQNLDFASYDTYASQENASAF LLNCDLWRNLKQGRPFWILETSPSYAASLESSAYPHADGYLQAEAVSSYALGSQGFCY WLWRQQRSGSEISHGSVLSAWGEPTIGYQNVLAVERARKEIEPIILSTEPVQAEAAMT YSDRAKAFIKTEPHRGLRHRSLVTHFYERILNTGIHRDLIPEGAPLDGYRLLFTPFVP YLSSEFIKKASAFAEAGGIWITGPLTGGRTCEHTIHTDCGLGELEKTSGIKTLFTFPM NENVNTGKAFGITAPLGLWSAVFDTESGNTLGTVEAGPGAGHAFLTERNYGEGKIVML GSLPSGKEGDAMLEALVRHYAEEAVISSRSDVTPGTIVAPRIGENGLVWIVVNMDGKG GSVTLPESGTDLLTHRLEKAGRLAVGPHEYRVIQFDNHS*" gene 774799..776790 /gene="rhgZ" /locus_tag="BSU_07080" /old_locus_tag="BSU07080" CDS 776834..779407 /gene="yetA" /locus_tag="BSU_07090" /old_locus_tag="BSU07090" /EC_number="3.1.-.-" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative enzyme" /protein_id="NP_388590.2" /db_xref="EnsemblGenomes-Gn:BSU07090" /db_xref="EnsemblGenomes-Tr:CAB12528" /db_xref="SubtiList:BG12861" /db_xref="UniProtKB/Swiss-Prot:O31530" /translation="MKKIKWLSGQPKVTSGVTWGMPWKKGELKKGDRLALMNENAETR YVQSEPSAYWPDGSIKWTKHAAVFGGQENQSFTVHKREVPQPTESLSILETEHDIQVD TGALVCTIHKTGSDFIQSLQINGKPIAAGGRLVAIRETRKESAAKMVLLHERSVSFIK RAAIEQSGPVKAVVKIEGVHVLHKTYEEWLPFVIRLTFYAGLSEIGLVHTQLIDRSGK LEFVKGLGIEFDLFLEGEPYNRHFRFAGEKGMYKEPAQLFGTRKFNERYPLYEKQING EMLSPDEEHKEWFAHGTQNAVWDDVKIVQDSSDHYSLSKRTGKDYAWVGMLHGSRAKG LCYAGGKNGGVALGLRYFFEKYPSALEITGLAGSRPKMTIWLWPPDGEAMDLRHYTGN THVASAYEGFDEMRSDPTGIANTNEISLACFSHMPSDEVLNALADKWQAPPLIVCEPD VYYESKALGVWSIIDTSHPLKKELEEQLDAAFLFYKKEVEQRRWYGFWHYGDVMHTYD PIRHMWRYDLGGYAWQNNELVPTLWLWQAFFRSGREDIFRMAEAMTRHTSETDSFHLG EYAGLGSRHNVVHWGCGCKEARISMAGLHKFYYYLTGDDRTGDLLTEVKDADYALVKT DPMRAFYEKGKHPTHARTGPDWAAFCSNWLAEWERTENSEYLKKIETGINCLKRLPLR LLSGPTFEYDPATSMLHHMGDGIAGGYHMIIAFGAPQVWMELAELLDDWEWEDMLSEF GEFYTLSDEEKRKKSGGALHDGHFHWPMFAAGMTAYAARKKQDPHLAAKAWNLLLEDK LSHTPLPIKPERIETWTQLEELPWVTTNTVSQWCLNVIAALELIGDSLPAKKETSGKK G*" gene 776834..779407 /gene="yetA" /locus_tag="BSU_07090" /old_locus_tag="BSU07090" promotor_-10 complement(778156..778174) /Source="Nicolas_upshift_promotors" /id="U535" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.916083916083916" /psig="0.916083916083916" /xcortree=961 /SigmaFactorBS="tgtcaatgatgctccataccccgagtgcttttgaTTCGTAat agacgtccggctcGCATACAATGAGCGGGGGCgcctgccatttgtcagccagcgcatt g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(778169) /Source="Nicolas_upshifts" /id="U535" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.916083916083916" /psig="0.916083916083916" /xcortree=961 /SigmaFactorBS="tgtcaatgatgctccataccccgagtgcttttgaTTCGTAat agacgtccggctcGCATACAATGAGCGGGGGCgcctgccatttgtcagccagcgcatt g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(778190..778195) /Source="Nicolas_upshift_promotors" /id="U535" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.916083916083916" /psig="0.916083916083916" /xcortree=961 /SigmaFactorBS="tgtcaatgatgctccataccccgagtgcttttgaTTCGTAat agacgtccggctcGCATACAATGAGCGGGGGCgcctgccatttgtcagccagcgcatt g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" CDS 779529..781037 /gene="lplA" /locus_tag="BSU_07100" /old_locus_tag="BSU07100" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:7921237" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7921237; Product type lp: lipoprotein" /codon_start=1 /transl_table=11 /product="lipoprotein transporter binding protein for alpha-galacturonides" /protein_id="NP_388591.1" /db_xref="EnsemblGenomes-Gn:BSU07100" /db_xref="EnsemblGenomes-Tr:CAB12529" /db_xref="GOA:P37966" /db_xref="InterPro:IPR006059" /db_xref="SubtiList:BG10434" /db_xref="UniProtKB/Swiss-Prot:P37966" /translation="MKIRMRKKWMALPLAAMMIAGCSHSETSNSASGSKDTIKIMAPL LSPESPSDKSPSLKALEKYTGKEIKVTWVPDSSYNDKFNIVMASGEMPHAIVIKDKSA GFIKSVKAGAFWELSPYLKDYKNLSQADEKILKNSSVNGEVYGIYRTRDLIRACMIIR TDWLKNVGLDMPETLDDFYEVLKAFKEKDPDGNGKDDTYGMVVPKWMGLGNGSPWDVL QIWFGAPNRYGVENGKLIPDFTTKEYMDALTFFKKLYDEGLINKDFAVMDSAKWNDPV VKGKAGVIVDTGSRASQIQSAMEEADESNKDIIDIVGSLEGPNGKRTFPTSGYSGMIT IPKSSVKTEKELKEVLSFLDKMNDKEAQILTNNGVKGRNYELKDGVFTSLEKNNKSLL YEHEGLAQFSMSIPKSEYYIEDQKTKLFQHRKDIITEGEKIAVFNPAESLVSDVYTQK GAQLDNIILDARTQFIIGEIDEKGFDDAVELWKKSGGNELMKDLNKLYQSSK*" gene 779529..781037 /gene="lplA" /locus_tag="BSU_07100" /old_locus_tag="BSU07100" CDS 781092..782048 /gene="lplB" /locus_tag="BSU_07110" /old_locus_tag="BSU07110" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2b: Function from indirect experimental evidences (e.g. phenotypes); PubMedId: 10869078, 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="ABC transporter (permease) for alpha-galacturonides" /protein_id="NP_388592.1" /db_xref="EnsemblGenomes-Gn:BSU07110" /db_xref="EnsemblGenomes-Tr:CAB12530" /db_xref="GOA:P39128" /db_xref="InterPro:IPR000515" /db_xref="InterPro:IPR035906" /db_xref="SubtiList:BG10435" /db_xref="UniProtKB/Swiss-Prot:P39128" /translation="METVPKKRDAPVLTAGKGISWMAALKRDKWLYLLLIPGLLYFLI FKYLPMWGVLIAFKDYSPYLGFWKSEWVGFDYFKDFFMNPDFFRLLRNTLMLASLDLL FAFPAPLILALLLNEVRKAVYKRCIQTFIYVPHFVSWTIVVSITFVFFTVDTGVINKL IMSLTGEQISFLSDADWFRPMIVMQSIWKETGWGTILFLAALATVDQEQYEAAIMDGA GRFRRMWHITLPAIRSTIIVLLILRIGSFLNLGFEQVYLMTNSLNRSVADIFDTYVYM MGITQGAYSYSTAVGLFKSVVGIILIFGANYIAKKFDQEGLF*" gene 781092..782048 /gene="lplB" /locus_tag="BSU_07110" /old_locus_tag="BSU07110" downshifts complement(781366) /Source="Nicolas_upshifts" /id="D344" /incds=1 /nref=1 /ntot=8 /MaxReadThrough="1.59638" /MaxDrop="4.19822" /score="13.9744253" /energy="-20.3" /TU="NA" /idTUdmin="U538" /TUdmin=2068 /isTUend="FALSE" promotor_no_box complement(781392..781492) /Source="Nicolas_upshift_promotors" /id="U536" /multdbtbs="-" /comp="M21" /sig="Sig-" /pcomp="0.544455544455544" /psig="0.002997002997003" /xcortree=1476 /SigmaFactorBS="ggtacgtaaataaaggtttggatacatcttttatacacggcc tttcttacctcattcaaaagcagagccaaaatgagaggcgcgggaaaggcaaacaaaa g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_no_box" upshifts complement(781432) /Source="Nicolas_upshifts" /id="U536" /multdbtbs="-" /comp="M21" /sig="Sig-" /pcomp="0.544455544455544" /psig="0.002997002997003" /xcortree=1476 /SigmaFactorBS="ggtacgtaaataaaggtttggatacatcttttatacacggcc tttcttacctcattcaaaagcagagccaaaatgagaggcgcgggaaaggcaaacaaaa g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" CDS 782062..782949 /gene="lplC" /locus_tag="BSU_07120" /old_locus_tag="BSU07120" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2b: Function from indirect experimental evidences (e.g. phenotypes); PubMedId: 10869078, 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="ABC transporter (permease) for alpha-galacturonides" /protein_id="NP_388593.1" /db_xref="EnsemblGenomes-Gn:BSU07120" /db_xref="EnsemblGenomes-Tr:CAB12531" /db_xref="GOA:P39129" /db_xref="InterPro:IPR000515" /db_xref="InterPro:IPR035906" /db_xref="SubtiList:BG10857" /db_xref="UniProtKB/Swiss-Prot:P39129" /translation="MAEIHTMHNTKAGRVFDVCNILFLGGVGAITILPFLYIIAGSFA TEAELAQRSFFIFPKTFTLDAYKYVFSTPTFLRSMGVSIFITVVGTAVQLFFTFTMAY PLAKRHVKGRNLLLNLVIFSMLFSGGMIPTYLVVKSLGLLDTYWALILPMAINPFNLI IIKNFFQQLPRELEESAKIDGCSEIGVFWRIALPLSKPVIATFALFYAVGIWNDFFHA LLYINDSAKWPLQMVLRQVTILSDLTATNGDTMQNAVPPEQGIKLAVIVIATLPILAV YPFLQKHFAKGMLIGSVKG*" gene 782062..782949 /gene="lplC" /locus_tag="BSU_07120" /old_locus_tag="BSU07120" promotor_-35 782696..782701 /Source="Nicolas_upshift_promotors" /id="U537" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.99100899100899" /psig="0.99100899100899" /xcortree=1069 /SigmaFactorBS="ttgcgacctttgcgctgttttatgcggtcgggatttGGAATG atttcttccacgctcTCTTATATATCAATGACAGtgcaaaatggccgctgcaaatggt g" /listShort="lplD, S248, yetF" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 782717..782735 /Source="Nicolas_upshift_promotors" /id="U537" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.99100899100899" /psig="0.99100899100899" /xcortree=1069 /SigmaFactorBS="ttgcgacctttgcgctgttttatgcggtcgggatttGGAATG atttcttccacgctcTCTTATATATCAATGACAGtgcaaaatggccgctgcaaatggt g" /listShort="lplD, S248, yetF" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 782720 /Source="Nicolas_upshifts" /id="U537" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.99100899100899" /psig="0.99100899100899" /xcortree=1069 /SigmaFactorBS="ttgcgacctttgcgctgttttatgcggtcgggatttGGAATG atttcttccacgctcTCTTATATATCAATGACAGtgcaaaatggccgctgcaaatggt g" /listShort="lplD, S248, yetF" /GFF_Attribute="listLong" CDS 782958..784298 /gene="lplD" /locus_tag="BSU_07130" /old_locus_tag="BSU07130" /EC_number="3.2.1.67" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:23416295" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 23416295; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="alpha-galacturonidase" /protein_id="NP_388594.1" /db_xref="EnsemblGenomes-Gn:BSU07130" /db_xref="EnsemblGenomes-Tr:CAB12532" /db_xref="GOA:P39130" /db_xref="InterPro:IPR001088" /db_xref="InterPro:IPR015955" /db_xref="InterPro:IPR019802" /db_xref="InterPro:IPR022616" /db_xref="InterPro:IPR036291" /db_xref="PDB:3FEF" /db_xref="SubtiList:BG10858" /db_xref="UniProtKB/Swiss-Prot:P39130" /translation="MFHISTLDQIKIAYIGGGSQGWARSLMSDLSIDERMSGTVALYD LDFEAAQKNEVIGNHSGNGRWRYEAVSTLKKALSAADIVIISILPGSLDDMEVDVHLP ERCGIYQSVGDTVGPGGIIRGLRAVPIFAEIARAIRDYAPESWVINYTNPMSVCTRVL YKVFPGIKAIGCCHEVFGTQKLLAEMVTERLGIEVPRREDIRVNVLGINHFTWITKAS YRHIDLLPIFREFSAHYGESGYELEGECWRDSVFCSAHRVAFDLFETYGAIPAAGDRH LAEFLPGPYLKQPEVWKFHLTPISFRKQDRAEKRQETERLIVQQRGVAEKASGEEGVN IIAALLGLGELVTNVNMPNQGQVLNLPIQAIVETNAFITRNRVQPILSGALPKGVEML AARHISNQEAVADAGLTKDTGLAFQAFLNDPLVQIDRSDAEQLFNDMLQCIMQS*" gene 782958..784298 /gene="lplD" /locus_tag="BSU_07130" /old_locus_tag="BSU07130" S_feature complement(783392..785083) /Source="Nicolas_S_feature" /locus_tag="new_783392_785083_c" /HighExp="H2O2, dia15, Paraq, Lbexp, LBGexp, Salt, LPhT, GM 25, G150, dia0" /AntisenseName="yetF" /AntisenseCor="-0.25986434675098202" /AntisenseRegPval="-4.8" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.999" /TUlongSig="SigA" /TUlongPSig="0.993" /label="S247" S_feature 784299..784380 /Source="Nicolas_S_feature" /locus_tag="new_784299_784380" /HighExp="S5, S4, S6, S3, S7, S8, BT, LoTm, B36, G150" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigEF" /TUshortPSig="0.991" /TUlongSig="NA" /TUlongPSig="NA" /label="S248" CDS 784381..785076 /gene="yetF" /locus_tag="BSU_07140" /old_locus_tag="BSU07140" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="conserved membrane protein" /protein_id="NP_388595.1" /db_xref="EnsemblGenomes-Gn:BSU07140" /db_xref="EnsemblGenomes-Tr:CAB12533" /db_xref="GOA:O31533" /db_xref="InterPro:IPR007353" /db_xref="InterPro:IPR023090" /db_xref="PDB:3C6F" /db_xref="SubtiList:BG12862" /db_xref="UniProtKB/Swiss-Prot:O31533" /translation="MGNYLSVAVELVCGLGILFIILKLLGKTQFSQITPFDFISALIL GELVGNAVYDHEIKIKEIIFASLLWGVLIYIIEFITQKMKSSRKFLEGEPNIVIRKGE LQYKVMKKNKIDINQLQSLLRQAGSFSIQEVEYAILETNGMVSVLPKSDFDKPTNKDL QIPSKSVSLPITLIIDGEIVRDNLKEAGVDEQWLKQELKKKNIDKTEDVLFAEWHKNK PLYTVTYEQSRST*" gene 784381..785076 /gene="yetF" /locus_tag="BSU_07140" /old_locus_tag="BSU07140" downshifts 785074 /Source="Nicolas_upshifts" /id="D345" /incds=0 /nref=2 /ntot=24 /MaxReadThrough="1.32891" /MaxDrop="3.45213" /score="-0.176154378" /energy="-7.1" /TU="NA" /idTUdmin="U537" /TUdmin=0 /isTUend="TRUE" CDS complement(785113..785439) /gene="hmoA" /locus_tag="BSU_07150" /old_locus_tag="BSU07150" /EC_number="1.14.14.18" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:20180905, 21764939, 21873409" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 20180905, 21764939, 21873409; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="heme-degrading monooxygenase" /protein_id="NP_388596.2" /db_xref="EnsemblGenomes-Gn:BSU07150" /db_xref="EnsemblGenomes-Tr:CAB12534" /db_xref="GOA:O31534" /db_xref="InterPro:IPR007138" /db_xref="InterPro:IPR011008" /db_xref="SubtiList:BG12863" /db_xref="UniProtKB/Swiss-Prot:O31534" /translation="MFVQLRKMTVKEGFADKVIERFSAEGIIEKQEGLIDVTVLEKNV RRGDEEVVVMIRWESEDHWKQWEKSDAHIAGHKANKGKPKPDYLISTEVSMYHVRAVK QGTYNQ*" gene complement(785113..785439) /gene="hmoA" /locus_tag="BSU_07150" /old_locus_tag="BSU07150" downshifts complement(785128) /Source="Nicolas_upshifts" /id="D346" /incds=0 /nref=194 /ntot=248 /MaxReadThrough="4.01189" /MaxDrop="6.29183" /score="9.23596913" /energy="-9.1" /TU="U538" /idTUdmin="U539" /TUdmin=0 /isTUend="TRUE" downshifts 785426 /Source="Nicolas_upshifts" /id="D347" /incds=1 /nref=1 /ntot=45 /MaxReadThrough="1.96802" /MaxDrop="3.46057" /score="-7.34187128" /energy="-5" /TU="NA" /idTUdmin="U537" /TUdmin=352 /isTUend="FALSE" promotor_-10 complement(785462..785481) /Source="Nicolas_upshift_promotors" /id="U538" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.604395604395604" /psig="0.999000999001" /xcortree=2117 /SigmaFactorBS="tgttgcgcacggcggttcgattccgccctgcgctttcTTTGA CATtgagaatgaatttcATTTACAATTATTCATATGTgagaatgattggagtgagaca a" /listShort="yetG, S247" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(785480) /Source="Nicolas_upshifts" /id="U538" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.604395604395604" /psig="0.999000999001" /xcortree=2117 /SigmaFactorBS="tgttgcgcacggcggttcgattccgccctgcgctttcTTTGA CATtgagaatgaatttcATTTACAATTATTCATATGTgagaatgattggagtgagaca a" /listShort="yetG, S247" /GFF_Attribute="listLong" promotor_-35 complement(785496..785503) /Source="Nicolas_upshift_promotors" /id="U538" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.604395604395604" /psig="0.999000999001" /xcortree=2117 /SigmaFactorBS="tgttgcgcacggcggttcgattccgccctgcgctttcTTTGA CATtgagaatgaatttcATTTACAATTATTCATATGTgagaatgattggagtgagaca a" /listShort="yetG, S247" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(785543..785905) /gene="yetH" /locus_tag="BSU_07160" /old_locus_tag="BSU07160" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative lyase/dioxygenase" /protein_id="NP_388597.1" /db_xref="EnsemblGenomes-Gn:BSU07160" /db_xref="EnsemblGenomes-Tr:CAB12535" /db_xref="InterPro:IPR004360" /db_xref="InterPro:IPR029068" /db_xref="SubtiList:BG12864" /db_xref="UniProtKB/Swiss-Prot:O31535" /translation="MIKQIGTVAVYVEDQQKAKQFWTEKVGFDIAADHPMGPEASWLE VAPKGAETRLVIYPKAMMKGSEQMKASIVFECEDIFGTYEKMKTNGVEFLGEPNQMEW GTFVQFKDEDGNVFLLKE*" gene complement(785543..785905) /gene="yetH" /locus_tag="BSU_07160" /old_locus_tag="BSU07160" promotor_-10 complement(785928..785947) /Source="Nicolas_upshift_promotors" /id="U539" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.431568431568432" /psig="0.993006993006993" /xcortree=2376 /SigmaFactorBS="ttttaataatcagccggtttcccggctgatttttttATGTTA CttcggccgtaaaCAGGTTATAGTATTATTATCttttcaacttggaggtttccctatg a" /listShort="yetH, yetG" /listLong="S247" /label="promotor_-10" upshifts complement(785942) /Source="Nicolas_upshifts" /id="U539" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.431568431568432" /psig="0.993006993006993" /xcortree=2376 /SigmaFactorBS="ttttaataatcagccggtttcccggctgatttttttATGTTA CttcggccgtaaaCAGGTTATAGTATTATTATCttttcaacttggaggtttccctatg a" /listShort="yetH, yetG" /listLong="S247" promotor_-35 complement(785960..785966) /Source="Nicolas_upshift_promotors" /id="U539" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.431568431568432" /psig="0.993006993006993" /xcortree=2376 /SigmaFactorBS="ttttaataatcagccggtttcccggctgatttttttATGTTA CttcggccgtaaaCAGGTTATAGTATTATTATCttttcaacttggaggtttccctatg a" /listShort="yetH, yetG" /listLong="S247" /label="promotor_-35" S_feature complement(785976..786536) /Source="Nicolas_S_feature" /locus_tag="new_785976_786536_c" /HighExp="S8, S6, S7, S5, BT, B36, G/S, B60, Pyr, nit" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.99999400000000005" /TUshortSig="SigK" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S249" downshifts complement(786008) /Source="Nicolas_upshifts" /id="D348" /incds=0 /nref=38 /ntot=47 /MaxReadThrough="0.395850000000001" /MaxDrop="8.2984" /score="45.4672528" /energy="-13.7" /TU="NA" /idTUdmin="U540" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(786519..786538) /Source="Nicolas_upshift_promotors" /id="U540" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1291 /SigmaFactorBS="ctctctgagagcattccagcttcatatccttaggcGAATGCA CCAataagagtccgccCGCATAAACTGCAATGTACAgtttacaatgagaaaggacgtt a" /listShort="S249" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(786536) /Source="Nicolas_upshifts" /id="U540" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1291 /SigmaFactorBS="ctctctgagagcattccagcttcatatccttaggcGAATGCA CCAataagagtccgccCGCATAAACTGCAATGTACAgtttacaatgagaaaggacgtt a" /listShort="S249" /GFF_Attribute="listLong" promotor_-35 complement(786552..786561) /Source="Nicolas_upshift_promotors" /id="U540" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1291 /SigmaFactorBS="ctctctgagagcattccagcttcatatccttaggcGAATGCA CCAataagagtccgccCGCATAAACTGCAATGTACAgtttacaatgagaaaggacgtt a" /listShort="S249" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 786624..786631 /Source="Nicolas_upshift_promotors" /id="U541" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.915084915084915" /psig="0.999000999001" /xcortree=2437 /SigmaFactorBS="ggaatgctctcagagagcagaatcatttgatttttctctagt ctTATTCACAattccgatttatCATTTTATAATGAAAGTGCTtctattacgaaaaagg a" /listShort="yetI, yetI" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 786640 /Source="Nicolas_upshifts" /id="U541" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.915084915084915" /psig="0.999000999001" /xcortree=2437 /SigmaFactorBS="ggaatgctctcagagagcagaatcatttgatttttctctagt ctTATTCACAattccgatttatCATTTTATAATGAAAGTGCTtctattacgaaaaagg a" /listShort="yetI, yetI" /GFF_Attribute="listLong" promotor_-10 786644..786663 /Source="Nicolas_upshift_promotors" /id="U541" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.915084915084915" /psig="0.999000999001" /xcortree=2437 /SigmaFactorBS="ggaatgctctcagagagcagaatcatttgatttttctctagt ctTATTCACAattccgatttatCATTTTATAATGAAAGTGCTtctattacgaaaaagg a" /listShort="yetI, yetI" /GFF_Attribute="listLong" /label="promotor_-10" CDS 786689..787270 /gene="yetI" /locus_tag="BSU_07170" /old_locus_tag="BSU07170" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function; PubMedId : 11157946; Product type r: regulator" /pseudo /codon_start=1 /transl_table=11 /product="putative paralog of RsbR; N-terminal part of YetI" /db_xref="SubtiList:BG12865" /translation="MNIDQLLYQYIIDNTADITEKWFSLRCQLKGELYSASHLSEETK TLLTEQHTFTNITIASAFLEDQTDFQENMTKWAQNVAKNRVEQDVQVHEVVEAISNSR ISFWDAVATFIKENQEIVTNEDADRWNRIVNQSFDKLIIEFSEQYQKFMLMRLTSQQE LISELGCPVISIADGIGILPLIGSIDTKRHRSF*" gene 786689..787270 /gene="yetI" /locus_tag="BSU_07170" /old_locus_tag="BSU07170" /pseudo CDS 787264..787560 /gene="yetI" /locus_tag="BSU_07180" /old_locus_tag="BSU07180" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function; PubMedId : 11157946; Product type r: regulator" /pseudo /codon_start=1 /transl_table=11 /product="putative paralog of RsbR; C-terminal part of YetI" /db_xref="GOA:O31537" /db_xref="InterPro:IPR002645" /db_xref="InterPro:IPR036513" /db_xref="PSEUDO:CAB12537.2" /db_xref="SubtiList:BG12873" /db_xref="UniProtKB/Swiss-Prot:O31537" /translation="MLETVPVRCVERKITSLVVDLSGVPIVDTMVAQQLYNLSKTLFL LGVKAVFSGIRPDVAQTSIQLGLDFSEYETYGTLKQALENMGVRCIVEELEENK*" gene 787264..787560 /gene="yetI" /locus_tag="BSU_07180" /old_locus_tag="BSU07180" /pseudo downshifts 787552 /Source="Nicolas_upshifts" /id="D349" /incds=0 /nref=114 /ntot=215 /MaxReadThrough="1.06939" /MaxDrop="4.8053" /score="16.356572" /energy="-21.2" /TU="NA" /idTUdmin="U541" /TUdmin="-8" /isTUend="TRUE" promotor_-35 787631..787638 /Source="Nicolas_upshift_promotors" /id="U542" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.603396603396603" /psig=1 /xcortree=1743 /SigmaFactorBS="atatgcctttttgatttgaacagaaatcaccATTGATTTatc gaaaaaaacaTAATATTATAATTCTTATAAgaatactgtgaattaaaacctattcaac a" /listShort="yezD, yetJ, yetK" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 787652..787671 /Source="Nicolas_upshift_promotors" /id="U542" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.603396603396603" /psig=1 /xcortree=1743 /SigmaFactorBS="atatgcctttttgatttgaacagaaatcaccATTGATTTatc gaaaaaaacaTAATATTATAATTCTTATAAgaatactgtgaattaaaacctattcaac a" /listShort="yezD, yetJ, yetK" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 787660 /Source="Nicolas_upshifts" /id="U542" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.603396603396603" /psig=1 /xcortree=1743 /SigmaFactorBS="atatgcctttttgatttgaacagaaatcaccATTGATTTatc gaaaaaaacaTAATATTATAATTCTTATAAgaatactgtgaattaaaacctattcaac a" /listShort="yezD, yetJ, yetK" /GFF_Attribute="listLong" CDS 787715..787882 /gene="yezD" /locus_tag="BSU_07190" /old_locus_tag="BSU07190" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_388600.1" /db_xref="EnsemblGenomes-Gn:BSU07190" /db_xref="EnsemblGenomes-Tr:CAB12538" /db_xref="InterPro:IPR018743" /db_xref="SubtiList:BG12875" /db_xref="UniProtKB/Swiss-Prot:O31538" /translation="MVSKSTIDPEVIEKIISSLETLDFGTVQITVHDSQITQIEKIEK HRFSLKRKESK*" gene 787715..787882 /gene="yezD" /locus_tag="BSU_07190" /old_locus_tag="BSU07190" promotor_-35 787924..787931 /Source="Nicolas_upshift_promotors" /id="U543" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.985014985014985" /psig=1 /xcortree=2401 /SigmaFactorBS="taaagggcgtttgttttcattaaattctccttaaaaCATATA CAtatttcatccaatttTTATATAATAGACCTTTAAGatcattttttaggaggatttt t" /listShort="yetJ, yetK" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 787947..787966 /Source="Nicolas_upshift_promotors" /id="U543" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.985014985014985" /psig=1 /xcortree=2401 /SigmaFactorBS="taaagggcgtttgttttcattaaattctccttaaaaCATATA CAtatttcatccaatttTTATATAATAGACCTTTAAGatcattttttaggaggatttt t" /listShort="yetJ, yetK" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 787948 /Source="Nicolas_upshifts" /id="U543" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.985014985014985" /psig=1 /xcortree=2401 /SigmaFactorBS="taaagggcgtttgttttcattaaattctccttaaaaCATATA CAtatttcatccaatttTTATATAATAGACCTTTAAGatcattttttaggaggatttt t" /listShort="yetJ, yetK" /GFF_Attribute="listLong" CDS 787992..788636 /gene="calJ" /locus_tag="BSU_07200" /old_locus_tag="BSU07200" /function="7.4: Cations and iron carrying compounds" /experiment="publication(s) with functional evidences, PMID:15849754, 16850406, 16086852, 24904158" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15849754, 16850406, 16086852, 24904158; Product type t: transporter" /codon_start=1 /transl_table=11 /product="pH-sensitive calcium-leak permease (di-aspartyl pH sensor)" /protein_id="NP_388601.1" /db_xref="EnsemblGenomes-Gn:BSU07200" /db_xref="EnsemblGenomes-Tr:CAB12539" /db_xref="GOA:O31539" /db_xref="InterPro:IPR006214" /db_xref="PDB:4PGR" /db_xref="PDB:4PGS" /db_xref="PDB:4PGU" /db_xref="PDB:4PGV" /db_xref="PDB:4PGW" /db_xref="PDB:4TKQ" /db_xref="SubtiList:BG12866" /db_xref="UniProtKB/Swiss-Prot:O31539" /translation="MQATVHESKQSIMQRILTVFVFTLLIATVGLFIGQFVPVALMLP LSILEVAMIILAFWMRRRKAVGYAFVYTFAFVSGITLFPIVSHYASIAGAYVVLEAFG STFVIFAVLGTIGAKMKKDLSFLWSFLLVAVLALAVVGIFNIFSPLNSAAMMAYSVIG TIVFSLYILYDLNQIKHRHITEDLIPVMALSLYLDFINLFINLLRFFGILSSDD*" gene 787992..788636 /gene="calJ" /locus_tag="BSU_07200" /old_locus_tag="BSU07200" downshifts 788572 /Source="Nicolas_upshifts" /id="D350" /incds=1 /nref=1 /ntot=11 /MaxReadThrough="6.69003" /MaxDrop="2.5446" /score="-1.46791202" /energy="-10.7" /TU="U542,U543" /idTUdmin="U541" /TUdmin=1012 /isTUend="FALSE" downshifts 788616 /Source="Nicolas_upshifts" /id="D351" /incds=0 /nref=7 /ntot=127 /MaxReadThrough="5.33515" /MaxDrop="3.71552" /score="-1.46791202" /energy="-10.7" /TU="U542,U543" /idTUdmin="U542" /TUdmin="-990" /isTUend="FALSE" CDS 788636..789628 /gene="yetK" /locus_tag="BSU_07210" /old_locus_tag="BSU07210" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative efflux transporter" /protein_id="NP_388602.1" /db_xref="EnsemblGenomes-Gn:BSU07210" /db_xref="EnsemblGenomes-Tr:CAB12540" /db_xref="GOA:O31540" /db_xref="InterPro:IPR000620" /db_xref="SubtiList:BG12867" /db_xref="UniProtKB/Swiss-Prot:O31540" /translation="MKKRLSLDRRFLPYIKKAGGVLVKKQMGAYVSLAAAMAIVGSSV VVGKLMVERIPVFLSSGLRFLIASVVLLMLLFCIEKGFPALTKKDVFVLLVQSFTGVF LFSICLLYGVQYTTGTESGILTSTTPMLIGILSFFLLREKIEKKTLIGILLAVCGVMA INLFGAGSQDGTPHALFGNMLIIAAVIGEALFTLMAKLLSPHISALAISTFVSLFGFL FFLPFALFEASSFDYSVPTVLDWSYVLYYALFVTVLAFYLWYSGVTKVPAGVSGIFTS VLPVSAVILSGVILKEPFEFVHFIGIACVIGGIFVTVIKKKQPDAYPAAEEKTL*" gene 788636..789628 /gene="yetK" /locus_tag="BSU_07210" /old_locus_tag="BSU07210" downshifts 789562 /Source="Nicolas_upshifts" /id="D352" /incds=1 /nref=1 /ntot=18 /MaxReadThrough="4.14475" /MaxDrop="2.73453" /score="21.8095329" /energy="-10.7" /TU="U542,U543" /idTUdmin="U542" /TUdmin="-44" /isTUend="FALSE" downshifts 789606 /Source="Nicolas_upshifts" /id="D353" /incds=0 /nref=94 /ntot=214 /MaxReadThrough="0.120229999999999" /MaxDrop="4.45909" /score="21.8095329" /energy="-10.7" /TU="NA" /idTUdmin="U542" /TUdmin=0 /isTUend="TRUE" CDS complement(789652..790155) /gene="flvL" /locus_tag="BSU_07220" /old_locus_tag="BSU07220" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:19329649, 25209494" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 19329649, 25209494; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator (FlvL-flavonoids)" /protein_id="NP_388603.1" /db_xref="EnsemblGenomes-Gn:BSU07220" /db_xref="EnsemblGenomes-Tr:CAB12541" /db_xref="GOA:O31541" /db_xref="InterPro:IPR000835" /db_xref="InterPro:IPR023187" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG12868" /db_xref="UniProtKB/Swiss-Prot:O31541" /translation="MELKHLPKYKHITEHAETYANIDAGSLELFLSLFDISKKMNHVM EHYFAGRGLSEGKFKILMLLFDAKDHRLSPTELAKRSNVTKATITGLLDGLARDGFVS RRHHTEDKRKISIELTTEGKARLEQFLPGHFSKISAVMENYSDEEKDMFVKMLGDLFE RLSVFKD*" gene complement(789652..790155) /gene="flvL" /locus_tag="BSU_07220" /old_locus_tag="BSU07220" promotor_-10 complement(790180..790199) /Source="Nicolas_upshift_promotors" /id="U544" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.739260739260739" /psig="0.952047952047952" /xcortree=3006 /SigmaFactorBS="aagaaaagctgtcaatcatctccaagccAAGTTGCGttatgg ttttcccTCCTTTATAATCGTGTCACAacgaatgtacgggagctaattgcgatggaat t" /listShort="yetL" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(790188) /Source="Nicolas_upshifts" /id="U544" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.739260739260739" /psig="0.952047952047952" /xcortree=3006 /SigmaFactorBS="aagaaaagctgtcaatcatctccaagccAAGTTGCGttatgg ttttcccTCCTTTATAATCGTGTCACAacgaatgtacgggagctaattgcgatggaat t" /listShort="yetL" /GFF_Attribute="listLong" promotor_-35 complement(790213..790220) /Source="Nicolas_upshift_promotors" /id="U544" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.739260739260739" /psig="0.952047952047952" /xcortree=3006 /SigmaFactorBS="aagaaaagctgtcaatcatctccaagccAAGTTGCGttatgg ttttcccTCCTTTATAATCGTGTCACAacgaatgtacgggagctaattgcgatggaat t" /listShort="yetL" /GFF_Attribute="listLong" /label="promotor_-35" CDS 790318..791427 /gene="flvM" /locus_tag="BSU_07230" /old_locus_tag="BSU07230" /EC_number="1.14.13.-" /function="16.11: Scavenge (Catabolism)" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 25209494; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative flavin-dependent hydroxylase/monooxygenase acting on salicylate derivatives" /protein_id="NP_388604.1" /db_xref="EnsemblGenomes-Gn:BSU07230" /db_xref="EnsemblGenomes-Tr:CAB12542" /db_xref="GOA:O06489" /db_xref="InterPro:IPR002938" /db_xref="InterPro:IPR036188" /db_xref="SubtiList:BG12869" /db_xref="UniProtKB/Swiss-Prot:O06489" /translation="MKHMLIAGGGIGGLSAAISLRKAGFSVTLCEAASENRKTGAGIL QPQNALAVLKELGVFEDCCKHGFQTEWFKTFDEQGNLLFQVSESFLDDSLPGRNNILR KTLNDILMKHAEAVGVDIKWGKKVVAYEETAESVTALCEDGEKMQADILAGFDGIHSV VRDKMLQKETEKEHLGMGAWRFYIELPDYTFEDATFMYRSGDTQIGVVPLAQHAGYVF VLQPCTSDYWDEEDTRFDRVKEILSGFRGLDFVTKHMSKQHPVIFNKLEQVAVQEPWH KGRVIIGGDAAHAGAPTLAQGAAMAIEDAIVLAEELQNHADHETALQAYYKRRAPRAL KVQNLSSEIVRRRLKGEPGAEELIGECYAVLREGY*" gene 790318..791427 /gene="flvM" /locus_tag="BSU_07230" /old_locus_tag="BSU07230" downshifts 791410 /Source="Nicolas_upshifts" /id="D354" /incds=0 /nref=7 /ntot=67 /MaxReadThrough="0.0953400000000002" /MaxDrop="5.1482" /score="13.261567" /energy="-12.6" /TU="NA" /idTUdmin="U542" /TUdmin=1804 /isTUend="FALSE" CDS complement(791462..792532) /gene="yetN" /locus_tag="BSU_07240" /old_locus_tag="BSU07240" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 22333191" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_388605.1" /db_xref="EnsemblGenomes-Gn:BSU07240" /db_xref="EnsemblGenomes-Tr:CAB12543" /db_xref="InterPro:IPR025006" /db_xref="InterPro:IPR025012" /db_xref="SubtiList:BG12870" /db_xref="UniProtKB/Swiss-Prot:O06490" /translation="MDFEIRFLSFYVIQVEGKDEQANKQFKHFQTLDTGEFEESELKD FLDGELKKIVKRKADRHPQSEQVPTKIGHFIVEPGHELDSNPNYNMFNRARLAETKED FNELSEQFVRTYLDTSAVRGGVFLVASAVPRKYFDESFVFIMKCDFEPKVARISDASS LIKKVEMAITTKNMKSIQYPYMPEEGMVEEGELKIHQASHARYFEDFLKFVEYGESMP EIMKNQVMNMVQEHVYETFEDNSEELKQFEHDIEIWEASEKREIQERLDTHQVIEASA QIIEHTPEAQLKMKVGETEIKGLLADFGDSIHLAKVNGRYVALIEAETISFEKGSSPV EFYKPEGLHEVIERIRNKTEQD*" gene complement(791462..792532) /gene="yetN" /locus_tag="BSU_07240" /old_locus_tag="BSU07240" downshifts complement(791486) /Source="Nicolas_upshifts" /id="D355" /incds=0 /nref=45 /ntot=180 /MaxReadThrough="0.83729" /MaxDrop="4.28938" /score="0.323038441" /energy="-11.6" /TU="NA" /idTUdmin="U545" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(792563..792582) /Source="Nicolas_upshift_promotors" /id="U545" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.818181818181818" /psig="0.987012987012987" /xcortree=1835 /SigmaFactorBS="atttgactacatttccctttcatggtcatgattattccgttc tccCAATTGACgcatgatcgctgttTTTTCTATACTTGAGAAGCTgtacaatacgcga a" /listShort="yetN" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(792589) /Source="Nicolas_upshifts" /id="U545" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.818181818181818" /psig="0.987012987012987" /xcortree=1835 /SigmaFactorBS="atttgactacatttccctttcatggtcatgattattccgttc tccCAATTGACgcatgatcgctgttTTTTCTATACTTGAGAAGCTgtacaatacgcga a" /listShort="yetN" /GFF_Attribute="listLong" promotor_-35 complement(792597..792604) /Source="Nicolas_upshift_promotors" /id="U545" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.818181818181818" /psig="0.987012987012987" /xcortree=1835 /SigmaFactorBS="atttgactacatttccctttcatggtcatgattattccgttc tccCAATTGACgcatgatcgctgttTTTTCTATACTTGAGAAGCTgtacaatacgcga a" /listShort="yetN" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 792612..792618 /Source="Nicolas_upshift_promotors" /id="U546" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.976023976023976" /psig="0.976023976023976" /xcortree=728 /SigmaFactorBS="aaacagcgatcatgcgtcaattgggagaacGGAATAAtcatg accatgaaaGGGAAATGTAGTCAAATAGaaggcatttcatacggaaaggaatggttcg a" /listShort="yetO" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 792633..792651 /Source="Nicolas_upshift_promotors" /id="U546" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.976023976023976" /psig="0.976023976023976" /xcortree=728 /SigmaFactorBS="aaacagcgatcatgcgtcaattgggagaacGGAATAAtcatg accatgaaaGGGAAATGTAGTCAAATAGaaggcatttcatacggaaaggaatggttcg a" /listShort="yetO" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 792642 /Source="Nicolas_upshifts" /id="U546" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.976023976023976" /psig="0.976023976023976" /xcortree=728 /SigmaFactorBS="aaacagcgatcatgcgtcaattgggagaacGGAATAAtcatg accatgaaaGGGAAATGTAGTCAAATAGaaggcatttcatacggaaaggaatggttcg a" /listShort="yetO" /GFF_Attribute="listLong" CDS 792682..795867 /gene="cypD" /locus_tag="BSU_07250" /old_locus_tag="BSU07250" /EC_number="1.6.2.4" /EC_number="1.14.14.1" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1c: Function from experimental evidences in the studied genus; PubMedId: 11574077, 2544578, 21048857, 26452461; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="bifunctional P-450/NADPH-P450 reductase 1" /protein_id="NP_388606.1" /db_xref="EnsemblGenomes-Gn:BSU07250" /db_xref="EnsemblGenomes-Tr:CAB12544" /db_xref="GOA:O08394" /db_xref="InterPro:IPR001094" /db_xref="InterPro:IPR001128" /db_xref="InterPro:IPR001433" /db_xref="InterPro:IPR001709" /db_xref="InterPro:IPR003097" /db_xref="InterPro:IPR008254" /db_xref="InterPro:IPR017927" /db_xref="InterPro:IPR017938" /db_xref="InterPro:IPR017972" /db_xref="InterPro:IPR023206" /db_xref="InterPro:IPR029039" /db_xref="InterPro:IPR036396" /db_xref="SubtiList:BG12871" /db_xref="UniProtKB/Swiss-Prot:O08394" /translation="MKETSPIPQPKTFGPLGNLPLIDKDKPTLSLIKLAEEQGPIFQI HTPAGTTIVVSGHELVKEVCDEERFDKSIEGALEKVRAFSGDGLFTSWTHEPNWRKAH NILMPTFSQRAMKDYHEKMVDIAVQLIQKWARLNPNEAVDVPGDMTRLTLDTIGLCGF NYRFNSYYRETPHPFINSMVRALDEAMHQMQRLDVQDKLMVRTKRQFRYDIQTMFSLV DSIIAERRANGDQDEKDLLARMLNVEDPETGEKLDDENIRFQIITFLIAGHETTSGLL SFATYFLLKHPDKLKKAYEEVDRVLTDAAPTYKQVLELTYIRMILNESLRLWPTAPAF SLYPKEDTVIGGKFPITTNDRISVLIPQLHRDRDAWGKDAEEFRPERFEHQDQVPHHA YKPFGNGQRACIGMQFALHEATLVLGMILKYFTLIDHENYELDIKQTLTLKPGDFHIS VQSRHQEAIHADVQAAEKAAPDEQKEKTEAKGASVIGLNNRPLLVLYGSDTGTAEGVA RELADTASLHGVRTKTAPLNDRIGKLPKEGAVVIVTSSYNGKPPSNAGQFVQWLQEIK PGELEGVHYAVFGCGDHNWASTYQYVPRFIDEQLAEKGATRFSARGEGDVSGDFEGQL DEWKKSMWADAIKAFGLELNENADKERSTLSLQFVRGLGESPLARSYEASHASIAENR ELQSADSDRSTRHIEIALPPDVEYQEGDHLGVLPKNSQTNVSRILHRFGLKGTDQVTL SASGRSAGHLPLGRPVSLHDLLSYSVEVQEAATRAQIRELASFTVCPPHRRELEELSA EGVYQEQILKKRISMLDLLEKYEACDMPFERFLELLRPLKPRYYSISSSPRVNPRQAS ITVGVVRGPAWSGRGEYRGVASNDLAERQAGDDVVMFIRTPESRFQLPKDPETPIIMV GPGTGVAPFRGFLQARDVLKREGKTLGEAHLYFGCRNDRDFIYRDELERFEKDGIVTV HTAFSRKEGMPKTYVQHLMADQADTLISILDRGGRLYVCGDGSKMAPDVEAALQKAYQ AVHGTGEQEAQNWLRHLQDTGMYAKDVWAGI*" gene 792682..795867 /gene="cypD" /locus_tag="BSU_07250" /old_locus_tag="BSU07250" downshifts 795854 /Source="Nicolas_upshifts" /id="D356" /incds=0 /nref=1 /ntot=9 /MaxReadThrough="2.31156" /MaxDrop="2.91666" /score="9.17315362" /energy="-9.8" /TU="NA" /idTUdmin="U546" /TUdmin=44 /isTUend="FALSE" promotor_-35 795917..795922 /Source="Nicolas_upshift_promotors" /id="U547" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.841158841158841" /psig="0.841158841158841" /xcortree=1029 /SigmaFactorBS="agtcctttcgaaaaaatgGTGATCgcgctaaacattgatGCA TACAATAACTTCAGTCcgccggaagggcgggctgtctgcaaaacctatttttcgtttt t" /listShort="S250, ltaSA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 795938..795956 /Source="Nicolas_upshift_promotors" /id="U547" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.841158841158841" /psig="0.841158841158841" /xcortree=1029 /SigmaFactorBS="agtcctttcgaaaaaatgGTGATCgcgctaaacattgatGCA TACAATAACTTCAGTCcgccggaagggcgggctgtctgcaaaacctatttttcgtttt t" /listShort="S250, ltaSA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 795959 /Source="Nicolas_upshifts" /id="U547" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.841158841158841" /psig="0.841158841158841" /xcortree=1029 /SigmaFactorBS="agtcctttcgaaaaaatgGTGATCgcgctaaacattgatGCA TACAATAACTTCAGTCcgccggaagggcgggctgtctgcaaaacctatttttcgtttt t" /listShort="S250, ltaSA" /GFF_Attribute="listLong" promotor_-35 795987..795990 /Source="Nicolas_upshift_promotors" /id="U548" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.803196803196803" /psig=1 /xcortree=2603 /SigmaFactorBS="acttcagtccgccggaagggcgggctgtctgcaaaacctATT TttcgtttttgctagttTATGTTATTCTTATACTCGGtatctatttcttttttcaaag g" /listShort="S250, ltaSA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 796007..796026 /Source="Nicolas_upshift_promotors" /id="U548" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.803196803196803" /psig=1 /xcortree=2603 /SigmaFactorBS="acttcagtccgccggaagggcgggctgtctgcaaaacctATT TttcgtttttgctagttTATGTTATTCTTATACTCGGtatctatttcttttttcaaag g" /listShort="S250, ltaSA" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 796008..796313 /Source="Nicolas_S_feature" /locus_tag="new_796008_796313" /HighExp="H2O2, Paraq, Oxctl, Cold, Heat, LBGexp, G180, G150, HPh, LBGstat" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigEF" /TUshortPSig="1, 0.841" /TUlongSig="NA" /TUlongPSig="NA" /label="S250" upshifts 796008 /Source="Nicolas_upshifts" /id="U548" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.803196803196803" /psig=1 /xcortree=2603 /SigmaFactorBS="acttcagtccgccggaagggcgggctgtctgcaaaacctATT TttcgtttttgctagttTATGTTATTCTTATACTCGGtatctatttcttttttcaaag g" /listShort="S250, ltaSA" /GFF_Attribute="listLong" CDS 796314..798233 /gene="ltaSA" /locus_tag="BSU_07260" /old_locus_tag="BSU07260" /function="16.1: Circulate" /function="16.13: Shape" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 11544192, 15187182, 17434969, 17483484, 21255105, 27002131; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="exported glycerol phosphate lipoteichoic acid synthetase and anion-binding protein" /protein_id="NP_388607.2" /db_xref="EnsemblGenomes-Gn:BSU07260" /db_xref="EnsemblGenomes-Tr:CAB12545" /db_xref="GOA:Q797B3" /db_xref="InterPro:IPR000917" /db_xref="InterPro:IPR012160" /db_xref="InterPro:IPR017849" /db_xref="InterPro:IPR017850" /db_xref="SubtiList:BG12980" /db_xref="UniProtKB/Swiss-Prot:Q797B3" /translation="MKKLFSYKLSFFVLAVILFWAKTYLSYKTEFNLGVKGTTQEILL IFNPFSSAVFFLGLALLAKGRKSAIIMLIIDFLMTFVLYANILFYRFFDDFLTFPNIK QSGNVGNMGDGIFSIMAGHDIFYFLDIIILIAVLIWRPELKEYKMKKRFASLVILSGI ALFFINLHYAEKDRPQLLTRTFDRNYIVKYLGLYNYTIYDGVQTAQTETQRAYASSDD LTSVENYTTSHYAKPNAEYFGSAKGKNIIKIHLESFQSFLIDYKLNGEEVTPFLNKLA HGGEDVTYFDNFFHQTGQGKTSDAELTMDNSIFGLPEGSAFVTKGENTYQSLPAILDQ KEGYTSAVLHGDYKSFWNRDQIYKHIGYDKFFDASTYDMSDENVINMGLKDKPFFTES IPKLESLKQPFYAHLITLTNHYPFNLDEKDASLKKATTGDNTVDSYFQTARYLDEALE QFFKELKEAGLYDNSVIMIYGDHNGISENHNRAMKEILGKEITDYQNAQNQRVPLMIR VPGKKGGVNHTYGGEIDVMPTLLHLEGIDSQKYINFGTDLFSKDHDDTVAFRNGDFVT PKYTSVDNIIYDTKTGEKLKANEETKNLKTRVNQQLSLSDSVLYKDLLRFHKLNDFKA VDPSDYHYGKEKEIK*" gene 796314..798233 /gene="ltaSA" /locus_tag="BSU_07260" /old_locus_tag="BSU07260" downshifts 798232 /Source="Nicolas_upshifts" /id="D357" /incds=0 /nref=103 /ntot=261 /MaxReadThrough="1.69168" /MaxDrop="7.8227" /score="37.7648461" /energy="-24" /TU="NA" /idTUdmin="U547" /TUdmin=2 /isTUend="TRUE" promotor_-35 798321..798330 /Source="Nicolas_upshift_promotors" /id="U549" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1421 /SigmaFactorBS="tttttttggttatacaaccaacttgaaaaaatagattccatT TGGTCACCAaggctggctttctCTCATATCATTACAGTAGATtttgaaaccggattga a" /listShort="S251, yfnH, yfnG, yfnF, yfnE, yfnD" /GFF_Attribute="listLong" /label="promotor_-35" S_feature 798340..798468 /Source="Nicolas_S_feature" /locus_tag="new_798340_798468" /HighExp="BT, B36, S8, S7, G/S, Pyr, B60, S6, Glucon, MG 5" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigK" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S251" upshifts 798340 /Source="Nicolas_upshifts" /id="U549" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1421 /SigmaFactorBS="tttttttggttatacaaccaacttgaaaaaatagattccatT TGGTCACCAaggctggctttctCTCATATCATTACAGTAGATtttgaaaccggattga a" /listShort="S251, yfnH, yfnG, yfnF, yfnE, yfnD" /GFF_Attribute="listLong" promotor_-10 798344..798363 /Source="Nicolas_upshift_promotors" /id="U549" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1421 /SigmaFactorBS="tttttttggttatacaaccaacttgaaaaaatagattccatT TGGTCACCAaggctggctttctCTCATATCATTACAGTAGATtttgaaaccggattga a" /listShort="S251, yfnH, yfnG, yfnF, yfnE, yfnD" /GFF_Attribute="listLong" /label="promotor_-10" downshifts complement(798394) /Source="Nicolas_upshifts" /id="D358" /incds=0 /nref=2 /ntot=6 /MaxReadThrough="1.80969" /MaxDrop="4.63324" /score="20.6569889" /energy="-23.4" /TU="NA" /idTUdmin="U552" /TUdmin=4928 /isTUend="FALSE" CDS 798469..799233 /gene="spmH" /locus_tag="BSU_07270" /old_locus_tag="BSU07270" /EC_number="2.7.7.33" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:15634670, 16357223, 26577401" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15634670, 16357223, 26577401; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="glucose-1-phosphate cytidylyltransferase (sporulation)" /protein_id="NP_388608.1" /db_xref="EnsemblGenomes-Gn:BSU07270" /db_xref="EnsemblGenomes-Tr:CAB12546" /db_xref="GOA:O06486" /db_xref="InterPro:IPR005835" /db_xref="InterPro:IPR013446" /db_xref="InterPro:IPR029044" /db_xref="SubtiList:BG12979" /db_xref="UniProtKB/Swiss-Prot:O06486" /translation="MKAVILCGGKGTRMSEVTNDIPKPLAMIGGKPILWHIMKIYQYY GVNEFILLLGYKGEKIKEYFLDYEWKHNSLTLDSSTGEVQMLGQPETWKITFLETGVD TLTAGRILQAKDYIGDETFLLTYGDGLANINLFHLISYHQTKGAAATVTGIDKVSQFG TLTVEDGMAKTFSEKTSSDGIINGGFFVLSPKVFDYLPKDGNTMFEDEPLKNLAKDGE LAVYRHYGFWTAIDTYKNLLEVNKMWNQGQQVWKVW*" gene 798469..799233 /gene="spmH" /locus_tag="BSU_07270" /old_locus_tag="BSU07270" CDS 799240..800208 /gene="spmG" /locus_tag="BSU_07280" /old_locus_tag="BSU07280" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative CDP-sugar-dehydratase/epimerase" /protein_id="NP_388609.2" /db_xref="EnsemblGenomes-Gn:BSU07280" /db_xref="EnsemblGenomes-Tr:CAB12547" /db_xref="GOA:O06485" /db_xref="InterPro:IPR016040" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG12978" /db_xref="UniProtKB/Swiss-Prot:O06485" /translation="MSFWKNKNVFVTGCTGLLGSYLVKELIEQGANVTGLVRDHVPQS NLYQGEHIKKMNIVRGSLEDLAVIERALGEYEIDTVFHLAAQAIVGVANRNPISTFEA NILGTWNILEACRKHPLIKRVIVASSDKAYGDQENLPYDENMPLQGKHPYDVSKSCAD LISHTYFHTYGLPVCITRCGNLYGGGDLNFNRIIPQTIQLVLNGEAPEIRSDGTFVRD YFYIEDAVQAYLLLAEKMEENNLAGEAFNFSNEIQLTVLELVEKILKKMNSNLKPKVL NQGSNEIKHQYLSAEKARKLLNWTPAYTIDEGLEKTIEWYTEFFKK*" gene 799240..800208 /gene="spmG" /locus_tag="BSU_07280" /old_locus_tag="BSU07280" CDS 800232..801143 /gene="yfnF" /locus_tag="BSU_07290" /old_locus_tag="BSU07290" /EC_number="2.4.1.-" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative glycosyltransferase" /protein_id="NP_388610.1" /db_xref="EnsemblGenomes-Gn:BSU07290" /db_xref="EnsemblGenomes-Tr:CAB12548" /db_xref="InterPro:IPR005069" /db_xref="InterPro:IPR029044" /db_xref="SubtiList:BG12977" /db_xref="UniProtKB/Swiss-Prot:O06484" /translation="MTSAYCTVLSKGRLYQAVALFKSLEQVDQDSPIFILCMDEDTHR VLQKLKMKQLNLVPVAALENELLLKLKETRDQSEYCWTMKPIFLQAVLNSNPELERVT YIDGDLFFYADPSPIFENQPDCSVLLSRGDIVIPSFEKEQIDMLQRLLGRYNSGFISF KHDDAGTDCLEWWKERCLEECKNAPGEGKFGDQGYLDYMSELFPNVCDITTPGVNIGH WNYGQHTFSWKDGRIVLEDGSPLIFYHFSGYRIVSINEIKQIHETTRTDLPFVHELYQ ETLPHIIQHMQTLDPEFNGFASKDDNK*" gene 800232..801143 /gene="yfnF" /locus_tag="BSU_07290" /old_locus_tag="BSU07290" promotor_-35 801021..801030 /Source="Nicolas_upshift_promotors" /id="U550" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=1259 /SigmaFactorBS="tcagcatcaatgaaatcaaacagattcatgaaacaACCCGCA CAGatctgccgtttgTGCATGAACTGTATCAAGAGacactgccgcatatcattcagca c" /listShort="yfnE, yfnD" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 801043..801062 /Source="Nicolas_upshift_promotors" /id="U550" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=1259 /SigmaFactorBS="tcagcatcaatgaaatcaaacagattcatgaaacaACCCGCA CAGatctgccgtttgTGCATGAACTGTATCAAGAGacactgccgcatatcattcagca c" /listShort="yfnE, yfnD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 801046 /Source="Nicolas_upshifts" /id="U550" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=1259 /SigmaFactorBS="tcagcatcaatgaaatcaaacagattcatgaaacaACCCGCA CAGatctgccgtttgTGCATGAACTGTATCAAGAGacactgccgcatatcattcagca c" /listShort="yfnE, yfnD" /GFF_Attribute="listLong" CDS 801172..802350 /gene="yfnE" /locus_tag="BSU_07300" /old_locus_tag="BSU07300" /EC_number="2.4.1.-" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative glycosyltransferase (complex carbohydrate synthase)" /protein_id="NP_388611.1" /db_xref="EnsemblGenomes-Gn:BSU07300" /db_xref="EnsemblGenomes-Tr:CAB12549" /db_xref="GOA:O06483" /db_xref="InterPro:IPR001173" /db_xref="InterPro:IPR029044" /db_xref="SubtiList:BG12976" /db_xref="UniProtKB/Swiss-Prot:O06483" /translation="MKASVIIPAYNSKERLYNSLLSLNQQECDEEFEVIVADNGSEDG TLSMLESFQADFPLIFTRIKENRGIAYGRNQALRNARGDILIFHDSDMLAAKDLVAKH IKAHENEENLVVCGLFWKRIYSFYYERFEEEHKEQLAKLTGEMPKKDKQKLLEEADIK NGSFLDKSFDLDTDFIDVLKKILDEYGDDLKGYHMPWRFFITNNSSVKRKHVVDLGLF DEGIVRYGFEDYDLGIRLHQAGLTFRLRRDIVSVHQEHPSNCKSVDDIRANIAYMCDK YNNIRSLDVHLAFNGPFPPDMTNRIMADIQKLLESQKYDMLLNLFLELLHVVKERNID PDWRKKSPRVTAKSFDLQTVRKLLPKAKKKLGVNDFANALYALVNDLLHVDLRSLDVV *" gene 801172..802350 /gene="yfnE" /locus_tag="BSU_07300" /old_locus_tag="BSU07300" promotor_-35 801891..801897 /Source="Nicolas_upshift_promotors" /id="U551" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.383616383616384" /psig="0.913086913086913" /xcortree=307 /SigmaFactorBS="tcgggatcaggcttcatcaggccggATTGACCttcaggcttc gccgTGATATTGTCAGTGTTCATCaggaacatccaagcaattgtaagtctgtagacga t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 801912..801931 /Source="Nicolas_upshift_promotors" /id="U551" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.383616383616384" /psig="0.913086913086913" /xcortree=307 /SigmaFactorBS="tcgggatcaggcttcatcaggccggATTGACCttcaggcttc gccgTGATATTGTCAGTGTTCATCaggaacatccaagcaattgtaagtctgtagacga t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 801926 /Source="Nicolas_upshifts" /id="U551" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.383616383616384" /psig="0.913086913086913" /xcortree=307 /SigmaFactorBS="tcgggatcaggcttcatcaggccggATTGACCttcaggcttc gccgTGATATTGTCAGTGTTCATCaggaacatccaagcaattgtaagtctgtagacga t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" CDS 802351..803286 /gene="yfnD" /locus_tag="BSU_07310" /old_locus_tag="BSU07310" /EC_number="2.4.1.-" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative glycosyltransferase (complex carbohydrate synthase)" /protein_id="NP_388612.1" /db_xref="EnsemblGenomes-Gn:BSU07310" /db_xref="EnsemblGenomes-Tr:CAB12550" /db_xref="InterPro:IPR005069" /db_xref="InterPro:IPR029044" /db_xref="SubtiList:BG12975" /db_xref="UniProtKB/Swiss-Prot:O31542" /translation="MSTFHFSTIVSRTHIFKLMPMIHSLHEHCDDFHLYVLCVDQKAY ELLQHVPWEHVTFVQLHEMEDPELLKAKSNRTFHEYCWTLKPAFLFHVMSKWDDAEYF AHMDTDLFFFSDPARIFAENPTASLYLTDHRNSPRFMSYYDRTGRFNTGFVGAGNTKE AYEAVWQWRQDCIEFCTVEMDTERKTYGDQRYVEKWPEQFKGVHVVKSIGANTALWNI ENYKVGQKDGRVYIDETPLIFYHFSGFTLVTEKEFNLCWYYRIEDEATIKMIYMPYIL NLKRWIDEIQSAFPDFADGFIPKHAVPDTHFIQLD*" gene 802351..803286 /gene="yfnD" /locus_tag="BSU_07310" /old_locus_tag="BSU07310" downshifts 803158 /Source="Nicolas_upshifts" /id="D359" /incds=1 /nref=1 /ntot=52 /MaxReadThrough="5.41459" /MaxDrop="2.6465" /score="34.8532284" /energy="-15.2" /TU="U549,U550" /idTUdmin="U549" /TUdmin="-110" /isTUend="FALSE" downshifts 803268 /Source="Nicolas_upshifts" /id="D360" /incds=0 /nref=2 /ntot=30 /MaxReadThrough="2.32849" /MaxDrop="5.65066" /score="34.8532284" /energy="-15.2" /TU="NA" /idTUdmin="U549" /TUdmin=0 /isTUend="TRUE" downshifts complement(803309) /Source="Nicolas_upshifts" /id="D361" /incds=0 /nref=158 /ntot=249 /MaxReadThrough="1.15199" /MaxDrop="4.97014" /score="32.9697757" /energy="-15.2" /TU="NA" /idTUdmin="U552" /TUdmin=13 /isTUend="TRUE" CDS complement(803317..804546) /gene="yfnC" /locus_tag="BSU_07320" /old_locus_tag="BSU07320" /function="16.1: Circulate" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative efflux transporter" /protein_id="NP_388613.1" /db_xref="EnsemblGenomes-Gn:BSU07320" /db_xref="EnsemblGenomes-Tr:CAB12551" /db_xref="GOA:O06481" /db_xref="InterPro:IPR011701" /db_xref="InterPro:IPR020846" /db_xref="InterPro:IPR036259" /db_xref="SubtiList:BG12974" /db_xref="UniProtKB/Swiss-Prot:O06481" /translation="MAIAAPLKEKTVQKPGTTVYPILIIIGICHMLNDSLQAVIPAMF PILERSMSLTFTQLGIIAFTLNMVSSVMQPVVGWYTDKRPRPYALPVGLTASMLGILG LAFAPSFITILCCVFFIGLGSAIFHPEGSRVAYMAAGTKRGLAQSIYQVGGNSGQAMA PLITALILVPLGQFGAVWFTLVAALAVMFLMYIAKWYASRLGSLAQKSGKQKKTAENT AITKSVVSALIIIIFLIFARSWYTSAIGNFYTFYAMDTYHVSIQQAQSYIFVFLLFGA IGTFLGGPLADRFGKRFVILGSLLCSAPLAIVLPFAGPVLAYGVLALIGLVLMSSFSV TVVYAQELVPGKIGTMSGLTVGLAFGMGAIGAVALGALIDAAGLTPTMIAIAFLPVLG ILAFLLPSDQKLREWHS*" gene complement(803317..804546) /gene="yfnC" /locus_tag="BSU_07320" /old_locus_tag="BSU07320" promotor_-10 complement(804575..804594) /Source="Nicolas_upshift_promotors" /id="U552" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.909090909090909" /psig="0.997002997002997" /xcortree=2717 /SigmaFactorBS="ggctgacggtatttctttcataagaatcttttttccTCTTGA TAaattcttcaccttatGAATAATATGGTGGTATGCTttggttatatatgtaaggagg a" /listShort="yfnC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(804593) /Source="Nicolas_upshifts" /id="U552" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.909090909090909" /psig="0.997002997002997" /xcortree=2717 /SigmaFactorBS="ggctgacggtatttctttcataagaatcttttttccTCTTGA TAaattcttcaccttatGAATAATATGGTGGTATGCTttggttatatatgtaaggagg a" /listShort="yfnC" /GFF_Attribute="listLong" promotor_-35 complement(804610..804617) /Source="Nicolas_upshift_promotors" /id="U552" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.909090909090909" /psig="0.997002997002997" /xcortree=2717 /SigmaFactorBS="ggctgacggtatttctttcataagaatcttttttccTCTTGA TAaattcttcaccttatGAATAATATGGTGGTATGCTttggttatatatgtaaggagg a" /listShort="yfnC" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(804657..805364) /gene="pynN" /locus_tag="BSU_07330" /old_locus_tag="BSU07330" /EC_number="3.1.3.-" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2b: Function from indirect experimental evidences (e.g. phenotypes); Product type e: enzyme" /codon_start=1 /transl_table=11 /product="pyrimidine nucleotide phosphatase (promiscuous)" /protein_id="NP_388614.1" /db_xref="EnsemblGenomes-Gn:BSU07330" /db_xref="EnsemblGenomes-Tr:CAB12552" /db_xref="GOA:O06480" /db_xref="InterPro:IPR006439" /db_xref="InterPro:IPR011951" /db_xref="InterPro:IPR023198" /db_xref="InterPro:IPR023214" /db_xref="InterPro:IPR036412" /db_xref="PDB:3ED5" /db_xref="PDB:3I76" /db_xref="SubtiList:BG12973" /db_xref="UniProtKB/Swiss-Prot:O06480" /translation="MKRYRTLLFDVDDTILDFQAAEALALRLLFEDQNIPLTNDMKAQ YKTINQGLWRAFEEGKMTRDEVVNTRFSALLKEYGYEADGALLEQKYRRFLEEGHQLI DGAFDLISNLQQQFDLYIVTNGVSHTQYKRLRDSGLFPFFKDIFVSEDTGFQKPMKEY FNYVFERIPQFSAEHTLIIGDSLTADIKGGQLAGLDTCWMNPDMKPNVPEIIPTYEIR KLEELYHILNIENTVSC*" gene complement(804657..805364) /gene="pynN" /locus_tag="BSU_07330" /old_locus_tag="BSU07330" downshifts complement(804686) /Source="Nicolas_upshifts" /id="D362" /incds=0 /nref=25 /ntot=169 /MaxReadThrough="2.75071" /MaxDrop="4.28644" /score="1.09492978" /energy="-15.7" /TU="NA" /idTUdmin="U553" /TUdmin=0 /isTUend="TRUE" misc_feature complement(805387..805406) /Source="Nicolas_upshift_promotors" /id="U553" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.985014985014985" /psig="0.998001998001998" /xcortree=3118 /SigmaFactorBS="ttattaaacaaataatctcttttcagccggcggtgcctcacc cgccggctttttcctttttttaTGTGCTATACTTTGAATACAtatgagaaagggagac a" /listShort="yfnB" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(805410) /Source="Nicolas_upshifts" /id="U553" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.985014985014985" /psig="0.998001998001998" /xcortree=3118 /SigmaFactorBS="ttattaaacaaataatctcttttcagccggcggtgcctcacc cgccggctttttcctttttttaTGTGCTATACTTTGAATACAtatgagaaagggagac a" /listShort="yfnB" /GFF_Attribute="listLong" CDS complement(805456..806841) /gene="mtrA" /locus_tag="BSU_07340" /old_locus_tag="BSU07340" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:12022921, 15849754, 16850406, 17114254, 18632116" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12022921, 15849754, 16850406, 17114254, 18632116; Product type t : transporter" /codon_start=1 /transl_table=11 /product="methylthioribose permease" /protein_id="NP_388615.1" /db_xref="EnsemblGenomes-Gn:BSU07340" /db_xref="EnsemblGenomes-Tr:CAB12553" /db_xref="GOA:Q797A7" /db_xref="InterPro:IPR002293" /db_xref="SubtiList:BG12972" /db_xref="UniProtKB/Swiss-Prot:Q797A7" /translation="MSSLFRKKPLETLSAQSKSKSLARTLSAFDLTLLGIGCVIGTGI FVITGTVAATGAGPALIISFILAGLACALAAFCYAEFSSSIPISGSVYSYSYVTLGEL LAFLIGWDLMLEYVIALSAVATGWSSYFQSLLAGFNLHIPAALTGAPGSMAGAVFNLP AAVIILLITAIVSRGVKESTRFNNVIVLMKIAIILLFIIVGIGYVKPDNWSPFMPFGM KGVILSAATVFFAYLGFDAVSNASEEVKNPQKNMPVGIISALAVCTVLYIAVSLVLTG MMPYAKLNVGDPVSFALKFVGQDAVAGIISVGAIIGITTVMLALLYAQVRLTFAMSRD GLLPGLFAKVHPSFKTPFRNTWLTGIVAAGIAGFINLGTLAHLVNMGTLAAFTVISIA VIVLRKKHPEIKASFRVPFVPVVPIISAGICLWFMYSLPGVTWLSFVIWIAVGTLVYF LYSRKHSLLNK*" gene complement(805456..806841) /gene="mtrA" /locus_tag="BSU_07340" /old_locus_tag="BSU07340" downshifts complement(805478) /Source="Nicolas_upshifts" /id="D363" /incds=0 /nref=8 /ntot=91 /MaxReadThrough="3.68565" /MaxDrop="4.73728" /score="31.1617384" /energy="-15.4" /TU="U554" /idTUdmin="U554" /TUdmin="-770" /isTUend="FALSE" promotor_-10 complement(806890..806909) /Source="Nicolas_upshift_promotors" /id="U554" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.913086913086913" /psig=1 /xcortree=2397 /SigmaFactorBS="tgtttcgcttctatcatttaaagcagaaaaatatttTATTGA CTacgtcaaatttcgaCAATATAATACAACAAGAACtgcatataatgattagaatatt t" /listShort="yfnA, yfnB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(806907) /Source="Nicolas_upshifts" /id="U554" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.913086913086913" /psig=1 /xcortree=2397 /SigmaFactorBS="tgtttcgcttctatcatttaaagcagaaaaatatttTATTGA CTacgtcaaatttcgaCAATATAATACAACAAGAACtgcatataatgattagaatatt t" /listShort="yfnA, yfnB" /GFF_Attribute="listLong" promotor_-35 complement(806924..806931) /Source="Nicolas_upshift_promotors" /id="U554" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.913086913086913" /psig=1 /xcortree=2397 /SigmaFactorBS="tgtttcgcttctatcatttaaagcagaaaaatatttTATTGA CTacgtcaaatttcgaCAATATAATACAACAAGAACtgcatataatgattagaatatt t" /listShort="yfnA, yfnB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 807009..807016 /Source="Nicolas_upshift_promotors" /id="U555" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2800 /SigmaFactorBS="aacagcgttgtcgtatcataggatagtaatttttactaatcg tatATTCAATTttatgcaagatgaACCGATAGAAAAAATAGATtcgcccatattttga t" /listShort="yfmT, yfmS" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 807024 /Source="Nicolas_upshifts" /id="U555" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2800 /SigmaFactorBS="aacagcgttgtcgtatcataggatagtaatttttactaatcg tatATTCAATTttatgcaagatgaACCGATAGAAAAAATAGATtcgcccatattttga t" /listShort="yfmT, yfmS" /GFF_Attribute="listLong" promotor_-10 807030..807048 /Source="Nicolas_upshift_promotors" /id="U555" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2800 /SigmaFactorBS="aacagcgttgtcgtatcataggatagtaatttttactaatcg tatATTCAATTttatgcaagatgaACCGATAGAAAAAATAGATtcgcccatattttga t" /listShort="yfmT, yfmS" /GFF_Attribute="listLong" /label="promotor_-10" CDS 807091..808548 /gene="vdhT" /locus_tag="BSU_07350" /old_locus_tag="BSU07350" /EC_number="1.2.1.67" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1b: Function from experimental evidences in the studied species; PubMedId: 15033535, 26658822; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="vanillin dehydrogenase" /protein_id="NP_388616.1" /db_xref="EnsemblGenomes-Gn:BSU07350" /db_xref="EnsemblGenomes-Tr:CAB12554" /db_xref="GOA:O06478" /db_xref="InterPro:IPR015590" /db_xref="InterPro:IPR016161" /db_xref="InterPro:IPR016162" /db_xref="InterPro:IPR029510" /db_xref="SubtiList:BG12971" /db_xref="UniProtKB/Swiss-Prot:O06478" /translation="MFQYEELNKQFIGGKWQEGSSPNVLENKNPYTQKTFTTFRKATA DDVDEAYRAAALAKKKWDAVNPFEKRTILEKAVTYIEENEEAIIYLIMEELGGTRLKA AFEIGLVKNIIKEAATFPIRMEGKILPSTIDGKENRLYRVPAGVVGVISPFNFPFFLS MKSVAPALGAGNGVVLKPHEETPICGGTLIAKIFENAGIPAGLLNVVVTDIAEIGDSF VEHPVPRIISFTGSTKVGSYIGQLAMKHFKKPLLELGGNSAFIVLEDADIEYAVNAAV FSRFTHQGQICMSANRVLVHSSIYDKFLELYQAKVESLKVGDPMDPDTIIGPLINSRQ TDGLMKTVEQAIEEGAVPVKLGGFNGTIVEPTILKDVKPFMSIAKEELFGPVVSFMKF DSEDEAVDIANETPFGLSGAVHTSNLERGVAFAKRIETGMIHVNDTTINDEPNVAFGG EKQSGLGRLNGEWSLEEFTTLKWISVQHEKRSFPY*" gene 807091..808548 /gene="vdhT" /locus_tag="BSU_07350" /old_locus_tag="BSU07350" promotor_-10 complement(807884..807903) /Source="Nicolas_upshift_promotors" /id="U556" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1237 /SigmaFactorBS="ctgacatgcaaatctgcccttgatgtgtaaatcGGCTGAACA CcgccgcattgacCGCATATTCTATATCTGCATcctcaagtacgatgaaggcgctgtt c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(807898) /Source="Nicolas_upshifts" /id="U556" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1237 /SigmaFactorBS="ctgacatgcaaatctgcccttgatgtgtaaatcGGCTGAACA CcgccgcattgacCGCATATTCTATATCTGCATcctcaagtacgatgaaggcgctgtt c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(807916..807925) /Source="Nicolas_upshift_promotors" /id="U556" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1237 /SigmaFactorBS="ctgacatgcaaatctgcccttgatgtgtaaatcGGCTGAACA CcgccgcattgacCGCATATTCTATATCTGCATcctcaagtacgatgaaggcgctgtt c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" CDS 808562..809422 /gene="yfmS" /locus_tag="BSU_07360" /old_locus_tag="BSU07360" /function="16.5: Explore" /function="16.3: Control" /function="16.12: Sense" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15033535, 27899502; Product type rc: receptor" /codon_start=1 /transl_table=11 /product="chemotaxis sensory transducer (sensed target unknown)" /protein_id="NP_388617.1" /db_xref="EnsemblGenomes-Gn:BSU07360" /db_xref="EnsemblGenomes-Tr:CAB12555" /db_xref="GOA:O06477" /db_xref="InterPro:IPR004089" /db_xref="InterPro:IPR029151" /db_xref="SubtiList:BG12970" /db_xref="UniProtKB/Swiss-Prot:O06477" /translation="MELTINTEKETADILDAFIKVAPYLNSLVQDDITIGIYDTEKLL VNIPAKTFSLNVKAGDPLQEGDIITDAIRSNQKKTSMVPKELFGFPLIARAIPLHDEN GRVIGGVGLGTSLEESSKLHDVAESLSAVVEQTAAAISDISESINGFSTQMSGISSQA KKVSESAGEIADISVTVKGISDQSNLLGLNAAIEAARAGESGKGFSVVADEIRKLATH SKENVGQIDQITKKIHSLLKGLEESIESINQHTDGQAAAVEQISATMQEISGSAQHLA KMAEKALEEE*" gene 808562..809422 /gene="yfmS" /locus_tag="BSU_07360" /old_locus_tag="BSU07360" downshifts 809406 /Source="Nicolas_upshifts" /id="D364" /incds=0 /nref=208 /ntot=237 /MaxReadThrough="2.9987" /MaxDrop="6.02377" /score="31.9989755" /energy="-16.7" /TU="U555" /idTUdmin="U555" /TUdmin="-22" /isTUend="TRUE" promotor_-35 809490..809497 /Source="Nicolas_upshift_promotors" /id="U557" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.953046953046953" /psig=1 /xcortree=1991 /SigmaFactorBS="tatcctgcatttccatgaaattcgtctgacgtttTACTAGTT ttattccagcggcTGATTTAAAATGTACACATGaacttacgtgaggattgataggaac c" /listShort="yfmR, yfmQ" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 809511..809530 /Source="Nicolas_upshift_promotors" /id="U557" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.953046953046953" /psig=1 /xcortree=1991 /SigmaFactorBS="tatcctgcatttccatgaaattcgtctgacgtttTACTAGTT ttattccagcggcTGATTTAAAATGTACACATGaacttacgtgaggattgataggaac c" /listShort="yfmR, yfmQ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 809516 /Source="Nicolas_upshifts" /id="U557" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.953046953046953" /psig=1 /xcortree=1991 /SigmaFactorBS="tatcctgcatttccatgaaattcgtctgacgtttTACTAGTT ttattccagcggcTGATTTAAAATGTACACATGaacttacgtgaggattgataggaac c" /listShort="yfmR, yfmQ" /GFF_Attribute="listLong" CDS 809557..811446 /gene="ettA" /locus_tag="BSU_07370" /old_locus_tag="BSU07370" /EC_number="3.6.3.-" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 10715006, 16109936, 18848624, 19948254, 24389465, 24389466; Product type r : regulator" /codon_start=1 /transl_table=11 /product="putative energy-dependent translational throttleA" /protein_id="NP_388618.1" /db_xref="EnsemblGenomes-Gn:BSU07370" /db_xref="EnsemblGenomes-Tr:CAB12556" /db_xref="GOA:O06476" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR017871" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR032524" /db_xref="InterPro:IPR032781" /db_xref="SubtiList:BG12969" /db_xref="UniProtKB/Swiss-Prot:O06476" /translation="MSILKAENLYKTYGDKTLFDHISFHIEENERIGLIGPNGTGKST LLKVIAGLESIEEGEITKSGSVQVEFLHQDPELPAGQTVLEHIYSGESAVMKTLREYE KALYELGKDPENEQRQKHLLAAQAKMDANNAWDANTLAKTVLSKLGVNDVTKPVNELS GGQKKRVAIAKNLIQPADLLILDEPTNHLDNETIEWLEGYLSQYPGAVMLVTHDRYFL NRVTNRIYELERGSLYTYKGNYEVFLEKRAEREAQAEQKETKRQNLLRRELAWLRRGA KARSTKQKARIDRVETLKEQTGPQSSGSLDFAIGSHRLGKQVIEAENVMIAYDGRMLV DRFNELVIPGERIGIIGPNGIGKTTLLNALAGRHTPDGGDITIGQTVRIGYYTQDHSE MNGELKVIDYIKETAEVVKTADGDMITAEQMLERFLFPRSMQQTYIRKLSGGEKRRLY LLQVLMQEPNVLFLDEPTNDLDTETLSVLEDYIDQFPGVVITVSHDRYFLDRVVDRLI VFEGNGVISRFQGSYSDYMEESKAKKAAPKPAAEEKTAEAEPKKKRKKLSYKDQLEWD GIEDKIAQLEEKHEQLEADIAAAGSDFGKIQELMAEQAKTAEELEAAMDRWTELSLMI EELES*" gene 809557..811446 /gene="ettA" /locus_tag="BSU_07370" /old_locus_tag="BSU07370" downshifts 811430 /Source="Nicolas_upshifts" /id="D365" /incds=0 /nref=2 /ntot=134 /MaxReadThrough="2.98669" /MaxDrop="2.72484" /score="30.3267801" /energy="-13.8" /TU="U557" /idTUdmin="U557" /TUdmin="-572" /isTUend="FALSE" misc_feature 811510..811529 /Source="Nicolas_upshift_promotors" /id="U558" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.5004995004995" /psig="0.99000999000999" /xcortree=1625 /SigmaFactorBS="gcagcaggccgcgctttttttcacataatggacaaaaacgaa ccggcctgctTATGTTAGGATAAAGTTGTGtgtcagcggcacatggaaaactaacgga g" /listShort="yfmQ" /listLong="yfmP, yfmO" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 811518 /Source="Nicolas_upshifts" /id="U558" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.5004995004995" /psig="0.99000999000999" /xcortree=1625 /SigmaFactorBS="gcagcaggccgcgctttttttcacataatggacaaaaacgaa ccggcctgctTATGTTAGGATAAAGTTGTGtgtcagcggcacatggaaaactaacgga g" /listShort="yfmQ" /listLong="yfmP, yfmO" CDS 811569..812015 /gene="yfmQ" /locus_tag="BSU_07380" /old_locus_tag="BSU07380" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 26483775" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_388619.1" /db_xref="EnsemblGenomes-Gn:BSU07380" /db_xref="EnsemblGenomes-Tr:CAB12557" /db_xref="GOA:O06475" /db_xref="InterPro:IPR019723" /db_xref="SubtiList:BG12968" /db_xref="UniProtKB/Swiss-Prot:O06475" /translation="MTWAIVMLILMSLVKIVLTCLPTGVIEWLLGKFEVHAKLSDENA SLSLDGKRLEGAEKQKVIDQFNEAIFLEKYYIYPGDEERYLHPENGGTPLVIDTKKGK KDVKLFVYRYDDHIDVVKQYKKKVIAYRVLSESLQKESLSVAGSLA*" gene 811569..812015 /gene="yfmQ" /locus_tag="BSU_07380" /old_locus_tag="BSU07380" downshifts complement(811571) /Source="Nicolas_upshifts" /id="D366" /incds=0 /nref=48 /ntot=154 /MaxReadThrough="1.16717" /MaxDrop="4.57866" /score="0.689181271" /energy="-10.2" /TU="NA" /idTUdmin="U559" /TUdmin=1 /isTUend="TRUE" promotor_-10 complement(811655..811658) /Source="Nicolas_upshift_promotors" /id="U559" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.597402597402597" /psig="0.063936063936064" /xcortree=1597 /SigmaFactorBS="tttccatctagagagagactcgcattttcgtcactcagcttg gCGtgcacttcaaatttgccGAGCagccattctatgacgcctgtaggaagacaggtta a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(811660) /Source="Nicolas_upshifts" /id="U559" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.597402597402597" /psig="0.063936063936064" /xcortree=1597 /SigmaFactorBS="tttccatctagagagagactcgcattttcgtcactcagcttg gCGtgcacttcaaatttgccGAGCagccattctatgacgcctgtaggaagacaggtta a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(811676..811677) /Source="Nicolas_upshift_promotors" /id="U559" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.597402597402597" /psig="0.063936063936064" /xcortree=1597 /SigmaFactorBS="tttccatctagagagagactcgcattttcgtcactcagcttg gCGtgcacttcaaatttgccGAGCagccattctatgacgcctgtaggaagacaggtta a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 812002 /Source="Nicolas_upshifts" /id="D367" /incds=0 /nref=254 /ntot=267 /MaxReadThrough="3.12706" /MaxDrop="7.87026" /score="13.6774886" /energy="-8" /TU="U558" /idTUdmin="U557" /TUdmin=0 /isTUend="TRUE" promotor_-35 812078..812085 /Source="Nicolas_upshift_promotors" /id="U560" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.606393606393606" /psig="0.999000999001" /xcortree=2124 /SigmaFactorBS="gtcttttttattgttttttaaaacttaACGTTTACgttaagg ttcaaaAGGTGTATAATGGTAACAGAaacggcgaagggggatttaccttggaatggat g" /listShort="yfmP, yfmO" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 812099..812118 /Source="Nicolas_upshift_promotors" /id="U560" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.606393606393606" /psig="0.999000999001" /xcortree=2124 /SigmaFactorBS="gtcttttttattgttttttaaaacttaACGTTTACgttaagg ttcaaaAGGTGTATAATGGTAACAGAaacggcgaagggggatttaccttggaatggat g" /listShort="yfmP, yfmO" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 812111 /Source="Nicolas_upshifts" /id="U560" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.606393606393606" /psig="0.999000999001" /xcortree=2124 /SigmaFactorBS="gtcttttttattgttttttaaaacttaACGTTTACgttaagg ttcaaaAGGTGTATAATGGTAACAGAaacggcgaagggggatttaccttggaatggat g" /listShort="yfmP, yfmO" /GFF_Attribute="listLong" CDS 812140..812562 /gene="copP" /locus_tag="BSU_07390" /old_locus_tag="BSU07390" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:14663075" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 14663075; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator (MerR family) of metal(copper) efflux transporter expression" /protein_id="NP_388620.1" /db_xref="EnsemblGenomes-Gn:BSU07390" /db_xref="EnsemblGenomes-Tr:CAB12558" /db_xref="GOA:O06474" /db_xref="InterPro:IPR000551" /db_xref="InterPro:IPR009061" /db_xref="SubtiList:BG12967" /db_xref="UniProtKB/Swiss-Prot:O06474" /translation="MEWMKIDQVAKRSGLTKRTIRFYEEIGLIPAPKRTDGGVRLYSE DDMEELEKVISTKEVLGFSLQELQHFMETSRQLELNKEGYLLSLDPKERKEKLEEIQE TLNHQLDLIDEKIRTFQSFKERLQGMKGKAERAIQSIE*" gene 812140..812562 /gene="copP" /locus_tag="BSU_07390" /old_locus_tag="BSU07390" downshifts 812398 /Source="Nicolas_upshifts" /id="D368" /incds=1 /nref=2 /ntot=135 /MaxReadThrough="4.24358" /MaxDrop="2.69696" /score="13.6774886" /energy="-8" /TU="U560" /idTUdmin="U558" /TUdmin=308 /isTUend="FALSE" CDS 812628..813818 /gene="copO" /locus_tag="BSU_07400" /old_locus_tag="BSU07400" /function="16.1: Circulate" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:14663075, 15849754, 16850406" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 14663075, 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="metal (copper) efflux transporter" /protein_id="NP_388621.1" /db_xref="EnsemblGenomes-Gn:BSU07400" /db_xref="EnsemblGenomes-Tr:CAB12559" /db_xref="GOA:O06473" /db_xref="InterPro:IPR001958" /db_xref="InterPro:IPR011701" /db_xref="InterPro:IPR020846" /db_xref="InterPro:IPR036259" /db_xref="SubtiList:BG12966" /db_xref="UniProtKB/Swiss-Prot:O06473" /translation="MDKTTQVNQKTGLLSQPKAVWAVAFACVISFMGIGLVDPILPAI AAQLHASPSEVSLLFTSYLLVTGFMMFFSGAISSRIGAKWTLILGLIFIIVFAGLGGS SSSIAQLVGYRGGWGLGNALFISTALAVIVGVSVGGSAQAIILYEAALGLGISVGPLA GGELGSISWRAPFFGVSVLMFIALIAISFMLPKLPKPAKRVGVFDAMKALKYKGLLTM AVSAFLYNFGFFILLAYSPFVLDLDEHGLGYVFFGWGLLLAITSVFTAPLVHKALGTV RSLVVLFIAFAAILVIMGIWTDHQTLIITCIVVAGAVLGMVNTIMTTAVMGSAPVERS IASSAYSSVRFIGGALAPWIAGMLSEHFTASTPYTVGGIVVFVGMLVLLMGRKHLAGI KAGH*" gene 812628..813818 /gene="copO" /locus_tag="BSU_07400" /old_locus_tag="BSU07400" downshifts complement(813882) /Source="Nicolas_upshifts" /id="D369" /incds=0 /nref=1 /ntot=10 /MaxReadThrough="-0.0437700000000003" /MaxDrop="2.92105" /score="-8.93016606" /energy="-11.6" /TU="NA" /idTUdmin="U562" /TUdmin=528 /isTUend="FALSE" CDS 814109..814264 /gene="yfmN" /locus_tag="BSU_07410" /old_locus_tag="BSU07410" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="NP_388622.1" /db_xref="EnsemblGenomes-Gn:BSU07410" /db_xref="EnsemblGenomes-Tr:CAB12560" /db_xref="SubtiList:BG12965" /db_xref="UniProtKB/Swiss-Prot:O06472" /translation="MDKAKPDEYDQKCLETLYQYIHSVMKNSFSRSSGLPLGKMRRIL SCLPKES*" gene 814109..814264 /gene="yfmN" /locus_tag="BSU_07410" /old_locus_tag="BSU07410" CDS complement(814384..815940) /gene="ettM" /locus_tag="BSU_07420" /old_locus_tag="BSU07420" /EC_number="3.6.3.-" /function="16.7: Manage energy" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 12486040, 16109936, 16684363, 22333191, 24389466; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative energy-sensing inhibitor of translation" /protein_id="NP_388623.2" /db_xref="EnsemblGenomes-Gn:BSU07420" /db_xref="EnsemblGenomes-Tr:CAB12571" /db_xref="GOA:O34512" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR017871" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR032781" /db_xref="SubtiList:BG12964" /db_xref="UniProtKB/Swiss-Prot:O34512" /translation="MSILSVKDLSHGFGDRAIFNNVSFRLLKGEHVGLIGANGEGKST FMNIITGKLEPDEGKVEWSKNVRVGYLDQHTVLEKGKSIRDVLKDAFHYLFAMEEEMN EIYNKMGEADPDELEKLLEEVGVIQDALTNNDFYVIDSKVEEIARGLGLSDIGLERDV TDLSGGQRTKVLLAKLLLEKPEILLLDEPTNYLDEQHIEWLKRYLQEYENAFILISHD IPFLNSVINLIYHVENQELTRYVGDYHQFMEVYEVKKQQLEAAYKKQQQEVAELKDFV ARNKARVSTRNMAMSRQKKLDKMDMIELAAEKPKPEFHFKPARTSGKLIFETKDLVIG YDSPLSRPLNLRMERGQKIALYGANGIGKTTLLKSLLGEIQPLEGSVERGEHIYTGYF EQEVKETNNNTCIEEVWSEFPSYTQYEIRAALAKCGLTTKHIESRVSVLSGGEKAKVR LCKLINSETNLLVLDEPTNHLDADAKEELKRALKEYKGSILLISHEPDFYMDIATETW NCESWTTKVL*" gene complement(814384..815940) /gene="ettM" /locus_tag="BSU_07420" /old_locus_tag="BSU07420" downshifts complement(814408) /Source="Nicolas_upshifts" /id="D370" /incds=0 /nref=173 /ntot=264 /MaxReadThrough="0.35675" /MaxDrop="5.82627" /score="21.7805812" /energy="-12" /TU="NA" /idTUdmin="U562" /TUdmin=2 /isTUend="TRUE" promotor_-35 815770..815776 /Source="Nicolas_upshift_promotors" /id="U561" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.994005994005994" /psig="0.994005994005994" /xcortree=894 /SigmaFactorBS="tttttgaccattcgacttttccCTCATCAggttcaagctttc cGGTAATAATATTcatgaaggttgattttccttcaccgtttgcgccgatcaagccgac g" /listShort="yfmL" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 815791..815802 /Source="Nicolas_upshift_promotors" /id="U561" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.994005994005994" /psig="0.994005994005994" /xcortree=894 /SigmaFactorBS="tttttgaccattcgacttttccCTCATCAggttcaagctttc cGGTAATAATATTcatgaaggttgattttccttcaccgtttgcgccgatcaagccgac g" /listShort="yfmL" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 815808 /Source="Nicolas_upshifts" /id="U561" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.994005994005994" /psig="0.994005994005994" /xcortree=894 /SigmaFactorBS="tttttgaccattcgacttttccCTCATCAggttcaagctttc cGGTAATAATATTcatgaaggttgattttccttcaccgtttgcgccgatcaagccgac g" /listShort="yfmL" /GFF_Attribute="listLong" promotor_-10 complement(815990..816009) /Source="Nicolas_upshift_promotors" /id="U562" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.854145854145854" /psig="0.927072927072927" /xcortree=2609 /SigmaFactorBS="gcaatttttctttttctttcctataCCTTTcaacattccgaa tccTCCTTTATAATCAAAAGGGTgaatattacacgccgattgtgcgtgtttgataacg a" /listShort="yfmM" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(815994) /Source="Nicolas_upshifts" /id="U562" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.854145854145854" /psig="0.927072927072927" /xcortree=2609 /SigmaFactorBS="gcaatttttctttttctttcctataCCTTTcaacattccgaa tccTCCTTTATAATCAAAAGGGTgaatattacacgccgattgtgcgtgtttgataacg a" /listShort="yfmM" /GFF_Attribute="listLong" promotor_-35 complement(816025..816029) /Source="Nicolas_upshift_promotors" /id="U562" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.854145854145854" /psig="0.927072927072927" /xcortree=2609 /SigmaFactorBS="gcaatttttctttttctttcctataCCTTTcaacattccgaa tccTCCTTTATAATCAAAAGGGTgaatattacacgccgattgtgcgtgtttgataacg a" /listShort="yfmM" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 816050..816053 /Source="Nicolas_upshift_promotors" /id="U563" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.608391608391608" /psig=1 /xcortree=2547 /SigmaFactorBS="attcggaatgttgaaaggtataggaaagaaaaagaaaaATTG cgttccgggcgaggtTTTGAGATACTATGGAATAGatttcaggaattgaggagaacaa a" /listShort="yfmL" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 816069..816088 /Source="Nicolas_upshift_promotors" /id="U563" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.608391608391608" /psig=1 /xcortree=2547 /SigmaFactorBS="attcggaatgttgaaaggtataggaaagaaaaagaaaaATTG cgttccgggcgaggtTTTGAGATACTATGGAATAGatttcaggaattgaggagaacaa a" /listShort="yfmL" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 816072 /Source="Nicolas_upshifts" /id="U563" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.608391608391608" /psig=1 /xcortree=2547 /SigmaFactorBS="attcggaatgttgaaaggtataggaaagaaaaagaaaaATTG cgttccgggcgaggtTTTGAGATACTATGGAATAGatttcaggaattgaggagaacaa a" /listShort="yfmL" /GFF_Attribute="listLong" CDS 816113..817243 /gene="yfmL" /locus_tag="BSU_07430" /old_locus_tag="BSU07430" /EC_number="3.6.1.-" /function="16.6: Maintain" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 11976317; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative ATP-dependent RNA helicase" /protein_id="NP_388624.1" /db_xref="EnsemblGenomes-Gn:BSU07430" /db_xref="EnsemblGenomes-Tr:CAB12572" /db_xref="GOA:O34750" /db_xref="InterPro:IPR001650" /db_xref="InterPro:IPR011545" /db_xref="InterPro:IPR014001" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG12963" /db_xref="UniProtKB/Swiss-Prot:O34750" /translation="MTQTWPFLHNAQSFIQENWNASGFQKPTPVQEQAAQLIMDGKDV IAESPTGTGKTLAYALPVLERIKPEQKHPQAVILAPSRELVMQIFQVIQDWKAGSELR AASLIGGANVKKQVEKLKKHPHIIVGTPGRVFELIKAKKLKMHEVKTIVLDETDQLVL PEHRETMKQIIKTTLRDRQLLCFSATLKKETEDVLRELAQEPEVLKVQRSKAEAGKVK HQYLICDQRDKVKLLQKLSRLEGMQALVFVRDIGNLSVYAEKLAYHHVELGVLHSEAK KMERAKIIATFEDGEFPLLLATDIAARGLDIENLPYVIHADIPDEDGYVHRSGRTGRA GKEGNVLSLVTKLEESKLKKMAKKLGVELSEAVYAGGKLKTK*" gene 816113..817243 /gene="yfmL" /locus_tag="BSU_07430" /old_locus_tag="BSU07430" downshifts 817226 /Source="Nicolas_upshifts" /id="D371" /incds=0 /nref=43 /ntot=133 /MaxReadThrough="2.93747" /MaxDrop="4.41385" /score="23.4253604" /energy="-5.9" /TU="NA" /idTUdmin="U563" /TUdmin="-12" /isTUend="TRUE" CDS 817311..817757 /gene="yfmK" /locus_tag="BSU_07440" /old_locus_tag="BSU07440" /EC_number="2.3.1.-" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative acetyltransferase" /protein_id="NP_388625.1" /db_xref="EnsemblGenomes-Gn:BSU07440" /db_xref="EnsemblGenomes-Tr:CAB12573" /db_xref="GOA:O34536" /db_xref="InterPro:IPR000182" /db_xref="InterPro:IPR016181" /db_xref="SubtiList:BG12962" /db_xref="UniProtKB/Swiss-Prot:O34536" /translation="MASIDRFQVMQEPELKILEHWFENEDTRRRMDGMLLLDEWYARV NKDKHDTVIMAYDGQLPAGMVVIEFGEERTYIGLIVNPLYRLKGYGKQILQKLMTEPD FTSVREWVACIEEDNRISLACFQAAGFTLEDTEPDEDGFLTLILRN*" gene 817311..817757 /gene="yfmK" /locus_tag="BSU_07440" /old_locus_tag="BSU07440" CDS complement(817810..818829) /gene="yfmJ" /locus_tag="BSU_07450" /old_locus_tag="BSU07450" /EC_number="1.-.-.-" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative oxidoreductase" /protein_id="NP_388626.1" /db_xref="EnsemblGenomes-Gn:BSU07450" /db_xref="EnsemblGenomes-Tr:CAB12574" /db_xref="GOA:O34812" /db_xref="InterPro:IPR011032" /db_xref="InterPro:IPR013149" /db_xref="InterPro:IPR020843" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG12961" /db_xref="UniProtKB/Swiss-Prot:O34812" /translation="MTASQQQIQLARRPQGIPVHEDFRFETIPVPEPKQGEVLVKTLY VSVDPYMRGRMQDTKSYVEPFALDKALSGGVIAEVVSDGNHLKKGDIVIGNLSWQEFS AVSESALRKIDTSLAPASAYLGILGMTGLTAYFGLLDIGRPKEGETVVVSGAAGAVGS TVGQIAKIKGARVVGIAGSDEKIDYLKQELQFDEAINYKTADDIQKALQNACPDGVDV YFDNVGGPISDAVMNLLNEFARIPVCGAISSYNAESEADDMGPRVQSKLIKTKSLMQG FIVSDYSDRFSEGAKQLAEWLKAGKLHYEETITEGFENIPDAFLGLFKGENKGKQLIK VSDPS*" gene complement(817810..818829) /gene="yfmJ" /locus_tag="BSU_07450" /old_locus_tag="BSU07450" downshifts complement(817820) /Source="Nicolas_upshifts" /id="D372" /incds=0 /nref=183 /ntot=252 /MaxReadThrough="2.26899" /MaxDrop="5.73395" /score="20.8047206" /energy="-12.8" /TU="NA" /idTUdmin="U564" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(818850..818869) /Source="Nicolas_upshift_promotors" /id="U564" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.654345654345654" /psig=1 /xcortree=3180 /SigmaFactorBS="accttttttgtatgccagcttacctTTTGTATTtcctctcct gtcCATGTTACAGTGGTGTCAACcaagtgataggaggatgaaaatgacagcatctcag c" /listShort="yfmJ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(818854) /Source="Nicolas_upshifts" /id="U564" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.654345654345654" /psig=1 /xcortree=3180 /SigmaFactorBS="accttttttgtatgccagcttacctTTTGTATTtcctctcct gtcCATGTTACAGTGGTGTCAACcaagtgataggaggatgaaaatgacagcatctcag c" /listShort="yfmJ" /GFF_Attribute="listLong" S_feature complement(818856..819310) /Source="Nicolas_S_feature" /locus_tag="new_818856_819310_c" /HighExp="S2, S1, Pyr, T4.0H, T0.0H, T-2.40H, T3.30H, T-1.40H, T-0.40H, T2.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.996" /TUlongSig="NA" /TUlongPSig="NA" /label="S252" promotor_-35 complement(818882..818889) /Source="Nicolas_upshift_promotors" /id="U564" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.654345654345654" /psig=1 /xcortree=3180 /SigmaFactorBS="accttttttgtatgccagcttacctTTTGTATTtcctctcct gtcCATGTTACAGTGGTGTCAACcaagtgataggaggatgaaaatgacagcatctcag c" /listShort="yfmJ" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 818948..818955 /Source="Nicolas_upshift_promotors" /id="U565" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.993006993006993" /psig="0.999000999001" /xcortree=1939 /SigmaFactorBS="atagatgagcttatgctttctacaagctctttTGTTTTAAaa gttctctttagTCATTTATCATTATTAGAAAacagaacagaaaaagagctcctgtaca c" /listShort="S253" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 818969..818988 /Source="Nicolas_upshift_promotors" /id="U565" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.993006993006993" /psig="0.999000999001" /xcortree=1939 /SigmaFactorBS="atagatgagcttatgctttctacaagctctttTGTTTTAAaa gttctctttagTCATTTATCATTATTAGAAAacagaacagaaaaagagctcctgtaca c" /listShort="S253" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 818976..820073 /Source="Nicolas_S_feature" /locus_tag="new_818976_820073" /HighExp="Etha, dia5, Diami, C30, dia15, T5.0H, S8, T3.0H, M0t90, LPhT" /AntisenseName="yfmI" /AntisenseCor="0.135213889213362" /AntisenseRegPval="-1.6" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S253" upshifts 818976 /Source="Nicolas_upshifts" /id="U565" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.993006993006993" /psig="0.999000999001" /xcortree=1939 /SigmaFactorBS="atagatgagcttatgctttctacaagctctttTGTTTTAAaa gttctctttagTCATTTATCATTATTAGAAAacagaacagaaaaagagctcctgtaca c" /listShort="S253" /GFF_Attribute="listLong" CDS complement(819311..820531) /gene="yfmI" /locus_tag="BSU_07460" /old_locus_tag="BSU07460" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative efflux transporter" /protein_id="NP_388627.1" /db_xref="EnsemblGenomes-Gn:BSU07460" /db_xref="EnsemblGenomes-Tr:CAB12575" /db_xref="GOA:O34440" /db_xref="InterPro:IPR011701" /db_xref="InterPro:IPR020846" /db_xref="InterPro:IPR036259" /db_xref="SubtiList:BG12960" /db_xref="UniProtKB/Swiss-Prot:O34440" /translation="MSKGYYSILFSQTTTNLGFSLYTMVVISFLFKMTNSTTIASMVT LISIIFRIFGSAILPLITIRLKLPLTIIISQLIQMLLLICLFYALLRTYSNQTLILVF IIISCISFFNGWFSPLKSAIIGEIISPDRRVKANGLLSTVDQTFQFVGWSLGGLIIAF LGEGYTIILTIFLLFTSLLSLLFCLPHGHANSVIREKNSPNKSIVSGWRYLFSQKKLR TIIIMDLIESWAGMIWIGSVSLAFVNEVLHKGESWWGFINGAYYLGSMIGGFIIYKLS ERFQNKLINFMLIGAVSYGSLTLIYGFISNSYLALILVLFMGPAYILRDLTQETLIQN ITTEQTRINIMSARSSLVQFIFMFSILAIGAISDFLGVRLVYVSAGILLLVSAIYGFS QLQFKKKVNKHISF*" gene complement(819311..820531) /gene="yfmI" /locus_tag="BSU_07460" /old_locus_tag="BSU07460" promotor_-10 complement(820568..820587) /Source="Nicolas_upshift_promotors" /id="U566" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.899100899100899" /psig="0.996003996003996" /xcortree=2925 /SigmaFactorBS="gtaaatagtttacaaggaaatttttTCTTTACTtttgttgtt ttaaggTGTTTAAATATGTTTAAGCTctttaccgagaaaaattattccaagggaggat a" /listShort="yfmI, S252, yfmJ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(820575) /Source="Nicolas_upshifts" /id="U566" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.899100899100899" /psig="0.996003996003996" /xcortree=2925 /SigmaFactorBS="gtaaatagtttacaaggaaatttttTCTTTACTtttgttgtt ttaaggTGTTTAAATATGTTTAAGCTctttaccgagaaaaattattccaagggaggat a" /listShort="yfmI, S252, yfmJ" /GFF_Attribute="listLong" promotor_-35 complement(820603..820610) /Source="Nicolas_upshift_promotors" /id="U566" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.899100899100899" /psig="0.996003996003996" /xcortree=2925 /SigmaFactorBS="gtaaatagtttacaaggaaatttttTCTTTACTtttgttgtt ttaaggTGTTTAAATATGTTTAAGCTctttaccgagaaaaattattccaagggaggat a" /listShort="yfmI, S252, yfmJ" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 820629..820636 /Source="Nicolas_upshift_promotors" /id="U567" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.96903096903097" /psig=1 /xcortree=480 /SigmaFactorBS="ccttaaaacaacaaaagtaaagaaaaaatttccttgtaaacT ATTTACTtttattctatttatTGTTATTGTTTATTTAAGTTctctgactattctatca a" /listShort="S254, yfmG, S256, S257, S258, S259, yfmA, yflT" /GFF_Attribute="listLong" /label="promotor_-35" S_feature 820648..820823 /Source="Nicolas_S_feature" /locus_tag="new_820648_820823" /HighExp="LoTm, T-1.10H, T-0.40H, S3, M9-stat, T0.0H, T-1.40H, BC, T2.0H, T5.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.98260400000000003" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S254" upshifts 820648 /Source="Nicolas_upshifts" /id="U567" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.96903096903097" /psig=1 /xcortree=480 /SigmaFactorBS="ccttaaaacaacaaaagtaaagaaaaaatttccttgtaaacT ATTTACTtttattctatttatTGTTATTGTTTATTTAAGTTctctgactattctatca a" /listShort="S254, yfmG, S256, S257, S258, S259, yfmA, yflT" /GFF_Attribute="listLong" promotor_-10 820651..820670 /Source="Nicolas_upshift_promotors" /id="U567" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.96903096903097" /psig=1 /xcortree=480 /SigmaFactorBS="ccttaaaacaacaaaagtaaagaaaaaatttccttgtaaacT ATTTACTtttattctatttatTGTTATTGTTTATTTAAGTTctctgactattctatca a" /listShort="S254, yfmG, S256, S257, S258, S259, yfmA, yflT" /GFF_Attribute="listLong" /label="promotor_-10" downshifts 820780 /Source="Nicolas_upshifts" /id="D373" /incds=0 /nref=34 /ntot=117 /MaxReadThrough="8.67835" /MaxDrop="8.45742" /score="4.02328636" /energy="-13.7" /TU="U567" /idTUdmin="U565" /TUdmin=748 /isTUend="FALSE" CDS 820867..822330 /gene="yfmG" /locus_tag="BSU_07480" /old_locus_tag="BSU07480" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative enzyme" /protein_id="NP_388629.1" /db_xref="EnsemblGenomes-Gn:BSU07480" /db_xref="EnsemblGenomes-Tr:CAB12577" /db_xref="InterPro:IPR005532" /db_xref="InterPro:IPR016187" /db_xref="SubtiList:BG12958" /db_xref="UniProtKB/Swiss-Prot:O34722" /translation="MTLLMQDHKSIYNKDIEILIEVEELITSVPENKKNDFKSLIDNR IMTLLNKIQHPVAAENVFGMCIAYPNTYIRYRLIDFVEKWVPYFSAVETIINLTQDPD DLVSFKAMDVCANHKIEESVAYLSSIIDDVRESISYPKKPVGLGAQKVLSTLLDIFGV EKHEELVMLKNYFDQNGILPNNFDFEEKIPQSLIEEFEKTEEDGMILIPGGFFEFGLN ENEIPDKTFNWKDAVPRQKVWLPPFFIDKYPVTNKDYDIFTEFIEENGHIFCHPNEPQ NKQHRRNTYWDDRYLDNHPVTGIDFYDAFAYARYKGKELPTEFQWEKAARGEKGNVWP WGDKFDPAKVQYAGSLYNEPITSLKSWRENLLKAHADKELNHLTSDIFEQNGESPYGV CGMIGGTWEWTRSELKTKRAFHPIFENVPFNSVNSFAVLKGGSFFSHPGLMFPSFRAK DIPFCRHNEMGIRCVKNIPVYKIRESINGPITNKAIY*" gene 820867..822330 /gene="yfmG" /locus_tag="BSU_07480" /old_locus_tag="BSU07480" S_feature complement(821232..822902) /Source="Nicolas_S_feature" /locus_tag="new_821232_822902_c" /HighExp="H2O2, C30, Salt, Lbstat, dia15, LPhT, dia5, Paraq, HiOs, Diami" /AntisenseName="yfmG" /AntisenseCor="-0.58045119682782798" /AntisenseRegPval="-24.9" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="0.998, 1" /TUlongSig="SigA" /TUlongPSig="0.996" /label="S255" S_feature 822331..822824 /Source="Nicolas_S_feature" /locus_tag="new_822331_822824" /HighExp="LoTm, T0.0H, T-1.40H, T-0.40H, T-2.40H, T-1.10H, Pyr, T-3.40H, SMMPr, T3.30H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S256" promotor_-35 822812..822817 /Source="Nicolas_upshift_promotors" /id="U568" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.982017982017982" /psig="0.982017982017982" /xcortree=758 /SigmaFactorBS="aaaagagtatctcgtatagaacataagaagaatgacgagttt tttaAGATTAtcatcaattatgtgaGAATAAAATATTATAAGGGaaaatgaaggctgt c" /listShort="S257" /GFF_Attribute="listLong" /label="promotor_-35" S_feature 822826..826091 /Source="Nicolas_S_feature" /locus_tag="new_822826_826091" /HighExp="LoTm, Pyr, B36, T3.30H, T2.0H, T-0.40H, T2.30H, B60, T4.0H, T3.0H" /AntisenseName="yfmE" /AntisenseCor="-0.61640022790163695" /AntisenseRegPval="-28.8" /CDS_PredictionProba="NA" /TUshortSig="SigEF, SigA" /TUshortPSig="0.982, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S257" upshifts 822826 /Source="Nicolas_upshifts" /id="U568" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.982017982017982" /psig="0.982017982017982" /xcortree=758 /SigmaFactorBS="aaaagagtatctcgtatagaacataagaagaatgacgagttt tttaAGATTAtcatcaattatgtgaGAATAAAATATTATAAGGGaaaatgaaggctgt c" /listShort="S257" /GFF_Attribute="listLong" promotor_-10 822833..822851 /Source="Nicolas_upshift_promotors" /id="U568" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.982017982017982" /psig="0.982017982017982" /xcortree=758 /SigmaFactorBS="aaaagagtatctcgtatagaacataagaagaatgacgagttt tttaAGATTAtcatcaattatgtgaGAATAAAATATTATAAGGGaaaatgaaggctgt c" /listShort="S257" /GFF_Attribute="listLong" /label="promotor_-10" CDS complement(822903..823703) /gene="fecF" /locus_tag="BSU_07490" /old_locus_tag="BSU07490" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:16672620, 22194458" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16672620, 22194458; Product type t: transporter" /codon_start=1 /transl_table=11 /product="iron-dicitrate ABC transporter (ATP-binding protein)" /protein_id="NP_388630.1" /db_xref="EnsemblGenomes-Gn:BSU07490" /db_xref="EnsemblGenomes-Tr:CAB12578" /db_xref="GOA:O34510" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR017871" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG12957" /db_xref="UniProtKB/Swiss-Prot:O34510" /translation="MGKLAADQLTLSYDSTVIIDGVDLKIEEGKITALIGANGCGKST ILKSLARLMAPKSGTVLLEGKDIHRQPSKEVAKKLAILPQSPQAPEGLTVEELCYFGR HPHKKLLSKHTQEDHDMVEWALEATGMIELKDRTLDALSGGQRQRAWISMALAQGTDL LLLDEPTTYLDISHQIEVLELLKKLNRDHGRTVVMVLHDLNQAAQYADYLISVLDGKI YNAGTPEDVFTQPFFREVFGLECCIMRSPIDQKPMCLPTGLCPKLRAK*" gene complement(822903..823703) /gene="fecF" /locus_tag="BSU_07490" /old_locus_tag="BSU07490" CDS complement(823716..824717) /gene="fecE" /locus_tag="BSU_07500" /old_locus_tag="BSU07500" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:15849754, 16672620, 16850406, 22194458" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15849754, 16672620, 16850406, 22194458; Product type t: transporter" /codon_start=1 /transl_table=11 /product="iron-dicitrate ABC transporter (permease)" /protein_id="NP_388631.1" /db_xref="EnsemblGenomes-Gn:BSU07500" /db_xref="EnsemblGenomes-Tr:CAB12579" /db_xref="GOA:O34832" /db_xref="InterPro:IPR000522" /db_xref="InterPro:IPR035568" /db_xref="SubtiList:BG12956" /db_xref="UniProtKB/Swiss-Prot:O34832" /translation="MKKTTRKQKRPLLAILILAVILIVLSVISIGIGALYISPDAVVT NLLGLDHSFEFIIQQYRLPRIILAILAGAGLAAAGAILQGVIRNPLASPDVVGISKGS GLAAMAVILIFPESPVYVLPFSAFAGAAIIAVLLLMIARKKSIQPSSLALSGIALGAV CHAGMQYMMVKFPGDVNAALIWLTGSLWGRNWEEVKLLAPWLLILFPIVCILIPKLDL MSLGDELAQGLGENANRLRFILIFTAVALAGSCVAVVGSIGFIGLLAPHIARRLTGEK AKYLLPASALIGAIILLIADTLGRGIMPPVEIPAGILTAVIGAPYFLYLLKFEARKQ* " gene complement(823716..824717) /gene="fecE" /locus_tag="BSU_07500" /old_locus_tag="BSU07500" promotor_-10 complement(824303..824322) /Source="Nicolas_upshift_promotors" /id="U569" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.954045954045954" /psig="0.998001998001998" /xcortree=2068 /SigmaFactorBS="gagtcgccggtatacgtgcttccgttctccgCATTTGCCgga gccgccattatTGCTGTACTATTATTAATGAtagcccgaaaaaagagcattcagccct c" /listShort="yfmF, S255" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(824315) /Source="Nicolas_upshifts" /id="U569" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.954045954045954" /psig="0.998001998001998" /xcortree=2068 /SigmaFactorBS="gagtcgccggtatacgtgcttccgttctccgCATTTGCCgga gccgccattatTGCTGTACTATTATTAATGAtagcccgaaaaaagagcattcagccct c" /listShort="yfmF, S255" /GFF_Attribute="listLong" promotor_-35 complement(824337..824344) /Source="Nicolas_upshift_promotors" /id="U569" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.954045954045954" /psig="0.998001998001998" /xcortree=2068 /SigmaFactorBS="gagtcgccggtatacgtgcttccgttctccgCATTTGCCgga gccgccattatTGCTGTACTATTATTAATGAtagcccgaaaaaagagcattcagccct c" /listShort="yfmF, S255" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(824714..825715) /gene="fecD" /locus_tag="BSU_07510" /old_locus_tag="BSU07510" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:12354229, 15849754, 16672620, 16850406, 22194458" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12354229, 15849754, 16672620, 16850406, 22194458; Product type t : transporter" /codon_start=1 /transl_table=11 /product="iron-dicitrate ABC transporter (permease)" /protein_id="NP_388632.1" /db_xref="EnsemblGenomes-Gn:BSU07510" /db_xref="EnsemblGenomes-Tr:CAB12580" /db_xref="GOA:O34933" /db_xref="InterPro:IPR000522" /db_xref="InterPro:IPR035568" /db_xref="SubtiList:BG12955" /db_xref="UniProtKB/Swiss-Prot:O34933" /translation="MYHSAKRRSSSRLMMFIIALIIFIFGLGLNLSVGASDISIIDSL KYLFVWDGSKEQLIISTLRLPRTLIGVFVGASLAVAGALMQAMTRNPLASPQIFGVNA GASLFVVASLVILPASPYSSVIFAFAGAAAGGAIVYMIASSGGMTPVKLALSGMAVHL FLSSMTQAIIILNESGEDVLYWMTGAIDGSNWQDVITIAPFSVIGIGLALVFSGSVSV LGLGDETAKGLGQNMNGIRILISLIILILSGASVAVAGPIGFVGLLVPHIVRKLIGEH YQYVLPFSALFGAILLVYADVLARWIAFPYESPVGIVTAIIGTPFFLYLARKGRNLK* " gene complement(824714..825715) /gene="fecD" /locus_tag="BSU_07510" /old_locus_tag="BSU07510" misc_feature complement(825785..825804) /Source="Nicolas_upshift_promotors" /id="U570" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.664335664335664" /psig="0.701298701298701" /xcortree=1492 /SigmaFactorBS="acacttggacaagattcagaggcatcaagtctagtgaaacaa gcgccaaagatgtgcttaaaAAAGTGTATAATAAATAGGAcaaatgagaagcgagggg a" /listShort="yfmD" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" CDS complement(825787..826734) /gene="fecC" /locus_tag="BSU_07520" /old_locus_tag="BSU07520" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:12354229, 15849754, 16672620, 16850406, 22194458" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12354229, 15849754, 16672620, 16850406, 22194458; Product type t : transporter" /codon_start=1 /transl_table=11 /product="iron-dicitrate ABC transporter (binding lipoprotein)" /protein_id="NP_388633.1" /db_xref="EnsemblGenomes-Gn:BSU07520" /db_xref="EnsemblGenomes-Tr:CAB12581" /db_xref="GOA:O34348" /db_xref="InterPro:IPR002491" /db_xref="SubtiList:BG12954" /db_xref="UniProtKB/Swiss-Prot:O34348" /translation="MRTYSNKLIAIMSVLLLACLIVSGCSSSQNNNGSGKSESKDSRV IHDEEGKTTVSGTPKRVVVLELSFLDAVHNLGITPVGIADDNKKDMIKKLVGSSIDYT SVGTRSEPNLEVISSLKPDLIIADAERHKNIYKQLKKIAPTIELKSREATYDETIDSF TTIAKALNKEDEGKEKLAEHKKVINDLKAELPKDENRNIVLGVARADSFQLHTSSSYD GEIFKMLGFTHAVKSDNAYQEVSLEQLSKIDPDILFISANEGKTIVDEWKTNPLWKNL KAVKNGQVYDADRDTWTRFRGIKSSETSAKDVLKKVYNK*" gene complement(825787..826734) /gene="fecC" /locus_tag="BSU_07520" /old_locus_tag="BSU07520" downshifts complement(825806) /Source="Nicolas_upshifts" /id="D374" /incds=0 /nref=41 /ntot=211 /MaxReadThrough="4.92983" /MaxDrop="4.53674" /score="-3.64310934" /energy="-13.9" /TU="U570,U573,U574" /idTUdmin="U570" /TUdmin="-198" /isTUend="FALSE" upshifts complement(825806) /Source="Nicolas_upshifts" /id="U570" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.664335664335664" /psig="0.701298701298701" /xcortree=1492 /SigmaFactorBS="acacttggacaagattcagaggcatcaagtctagtgaaacaa gcgccaaagatgtgcttaaaAAAGTGTATAATAAATAGGAcaaatgagaagcgagggg a" /listShort="yfmD" /GFF_Attribute="listLong" promotor_-35 826061..826066 /Source="Nicolas_upshift_promotors" /id="U571" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=1066 /SigmaFactorBS="atctgacttcacagcgtgtgtaaagcctAGCATTttaaagat ttctccgTCATAGGATGATGATGTATgaagctggaaggaatccgctcttgcaacgccg a" /listShort="S258, S259" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 826082..826100 /Source="Nicolas_upshift_promotors" /id="U571" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=1066 /SigmaFactorBS="atctgacttcacagcgtgtgtaaagcctAGCATTttaaagat ttctccgTCATAGGATGATGATGTATgaagctggaaggaatccgctcttgcaacgccg a" /listShort="S258, S259" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 826093..826718 /Source="Nicolas_S_feature" /locus_tag="new_826093_826718" /HighExp="LoTm, B36, S5, S6, S4, S7, S8, S3, BT, B60" /AntisenseName="yfmC" /AntisenseCor="-0.52042999587715499" /AntisenseRegPval="-19.3" /CDS_PredictionProba="NA" /TUshortSig="SigEF, SigA" /TUshortPSig="0.997, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S258" upshifts 826093 /Source="Nicolas_upshifts" /id="U571" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=1066 /SigmaFactorBS="atctgacttcacagcgtgtgtaaagcctAGCATTttaaagat ttctccgTCATAGGATGATGATGTATgaagctggaaggaatccgctcttgcaacgccg a" /listShort="S258, S259" /GFF_Attribute="listLong" misc_feature 826714..826733 /Source="Nicolas_upshift_promotors" /id="U572" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.905094905094905" /psig="0.997002997002997" /xcortree=1855 /SigmaFactorBS="acagccggatacaatgaggcaggcgagcaataaaacactcat gatggcaatcaaCTTGTTAGAATAGGTGCGCAtgtcattcttccttttttcagattta g" /listShort="S259" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" S_feature 826720..827251 /Source="Nicolas_S_feature" /locus_tag="new_826720_827251" /HighExp="LoTm, B36, S5, S4, S7, S6, S8, B60, S3, BT" /AntisenseName="yfmB" /AntisenseCor="-6.4915194654100006E-2" /AntisenseRegPval="-0.5" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigEF, SigA" /TUshortPSig="0.997, 0.997, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S259" upshifts 826720 /Source="Nicolas_upshifts" /id="U572" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.905094905094905" /psig="0.997002997002997" /xcortree=1855 /SigmaFactorBS="acagccggatacaatgaggcaggcgagcaataaaacactcat gatggcaatcaaCTTGTTAGAATAGGTGCGCAtgtcattcttccttttttcagattta g" /listShort="S259" /GFF_Attribute="listLong" promotor_-10 complement(826776..826795) /Source="Nicolas_upshift_promotors" /id="U573" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.645354645354645" /psig=1 /xcortree=2102 /SigmaFactorBS="aaaacgcagctttctttactaaaaaaaTATTGACAtgataag ccatgcTATTATAGTGTTACATGTGAtaatgattctcattactaaatctgaaaaaagg a" /listShort="yfmC, yfmD, yfmE, yfmF, S255" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(826783) /Source="Nicolas_upshifts" /id="U573" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.645354645354645" /psig=1 /xcortree=2102 /SigmaFactorBS="aaaacgcagctttctttactaaaaaaaTATTGACAtgataag ccatgcTATTATAGTGTTACATGTGAtaatgattctcattactaaatctgaaaaaagg a" /listShort="yfmC, yfmD, yfmE, yfmF, S255" /GFF_Attribute="listLong" promotor_-35 complement(826809..826816) /Source="Nicolas_upshift_promotors" /id="U573" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.645354645354645" /psig=1 /xcortree=2102 /SigmaFactorBS="aaaacgcagctttctttactaaaaaaaTATTGACAtgataag ccatgcTATTATAGTGTTACATGTGAtaatgattctcattactaaatctgaaaaaagg a" /listShort="yfmC, yfmD, yfmE, yfmF, S255" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(826843..827211) /gene="yfmB" /locus_tag="BSU_07530" /old_locus_tag="BSU07530" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 25651892" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_388634.1" /db_xref="EnsemblGenomes-Gn:BSU07530" /db_xref="EnsemblGenomes-Tr:CAB12582" /db_xref="InterPro:IPR021579" /db_xref="PDB:2EUC" /db_xref="SubtiList:BG12953" /db_xref="UniProtKB/Swiss-Prot:O34626" /translation="MQYFSPEQQYNAWIVSDLVKQIFHKRAGCSPGIHELAVFAEEHF HIDIDFVFSIIMNIGDIEFALTDEIEKKLSGYLSTLLPYVTADMFETSKANAHAFLSR RHGNAAYHLFVSDDAFMRKQ*" gene complement(826843..827211) /gene="yfmB" /locus_tag="BSU_07530" /old_locus_tag="BSU07530" S_feature complement(827212..827324) /Source="Nicolas_S_feature" /locus_tag="new_827212_827324_c" /HighExp="Etha, BC, Sw, M9-stat, T3.30H, T1.30H, T3.0H, T5.0H, T2.30H, T2.0H" /AntisenseName="yfmA" /AntisenseCor="5.8024036419347599E-2" /AntisenseRegPval="-0.5" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.996" /TUlongSig="NA" /TUlongPSig="NA" /label="S260" promotor_-10 complement(827313..827332) /Source="Nicolas_upshift_promotors" /id="U574" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.967032967032967" /psig="0.996003996003996" /xcortree=128 /SigmaFactorBS="gaacattgaagagaaaaacaggaggaatggtagTAGCTATTt gttttccgtcCATGGTAAAGTGATAGGAACgggacctattttcagaaaaatcaaaatt a" /listShort="S260, yfmB, yfmC, yfmD" /listLong="yfmE, yfmF, S255" /label="promotor_-10" upshifts complement(827324) /Source="Nicolas_upshifts" /id="U574" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.967032967032967" /psig="0.996003996003996" /xcortree=128 /SigmaFactorBS="gaacattgaagagaaaaacaggaggaatggtagTAGCTATTt gttttccgtcCATGGTAAAGTGATAGGAACgggacctattttcagaaaaatcaaaatt a" /listShort="S260, yfmB, yfmC, yfmD" /listLong="yfmE, yfmF, S255" promotor_-35 complement(827344..827351) /Source="Nicolas_upshift_promotors" /id="U574" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.967032967032967" /psig="0.996003996003996" /xcortree=128 /SigmaFactorBS="gaacattgaagagaaaaacaggaggaatggtagTAGCTATTt gttttccgtcCATGGTAAAGTGATAGGAACgggacctattttcagaaaaatcaaaatt a" /listShort="S260, yfmB, yfmC, yfmD" /listLong="yfmE, yfmF, S255" /label="promotor_-35" promotor_-35 827392..827398 /Source="Nicolas_upshift_promotors" /id="U575" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=221 /SigmaFactorBS="ctaccattcctcctgtttttctcttcaatgttctggaatcTG TTTCAggtacagacgatcGGGTATGAAAGAAATATAGaaaacatgaaggaggaatatc g" /listShort="yflT, S261, pel, yflS" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 827412..827430 /Source="Nicolas_upshift_promotors" /id="U575" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=221 /SigmaFactorBS="ctaccattcctcctgtttttctcttcaatgttctggaatcTG TTTCAggtacagacgatcGGGTATGAAAGAAATATAGaaaacatgaaggaggaatatc g" /listShort="yflT, S261, pel, yflS" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 827412 /Source="Nicolas_upshifts" /id="U575" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=221 /SigmaFactorBS="ctaccattcctcctgtttttctcttcaatgttctggaatcTG TTTCAggtacagacgatcGGGTATGAAAGAAATATAGaaaacatgaaggaggaatatc g" /listShort="yflT, S261, pel, yflS" /GFF_Attribute="listLong" CDS 827455..827802 /gene="yflT" /locus_tag="BSU_07550" /old_locus_tag="BSU07550" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1c: Function from experimental evidences in the studied genus; PubMedId: 12089032; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="heat stress induced protein" /protein_id="NP_388636.1" /db_xref="EnsemblGenomes-Gn:BSU07550" /db_xref="EnsemblGenomes-Tr:CAB12584" /db_xref="InterPro:IPR025889" /db_xref="SubtiList:BG19020" /db_xref="UniProtKB/Swiss-Prot:P80241" /translation="MKPVVKEYTNDEQLMKDVEELQKMGVAKEDVYVLAHDDDRTERL ADNTNANTIGAKETGFKHAVGNIFNKKGDELRNKIHEIGFSEDEAAQFEKRLDEGKVL LFVTDNEKVKAWA*" gene 827455..827802 /gene="yflT" /locus_tag="BSU_07550" /old_locus_tag="BSU07550" downshifts complement(827456) /Source="Nicolas_upshifts" /id="D375" /incds=0 /nref=6 /ntot=28 /MaxReadThrough="1.00082" /MaxDrop="4.87687" /score="-3.31058364" /energy="-3.6" /TU="NA" /idTUdmin="U570" /TUdmin="-1848" /isTUend="FALSE" downshifts 827798 /Source="Nicolas_upshifts" /id="D376" /incds=0 /nref=56 /ntot=197 /MaxReadThrough="6.41566" /MaxDrop="7.61596" /score="-1.88723414" /energy="-5.6" /TU="U575" /idTUdmin="U567" /TUdmin=0 /isTUend="TRUE" S_feature 827843..827923 /Source="Nicolas_S_feature" /locus_tag="new_827843_827923" /HighExp="Etha, Salt, B36, LoTm, Heat, B60, M9-stat, S8, C30, LPhT" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigB" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S261" misc_feature 827924..827943 /Source="Nicolas_upshift_promotors" /id="U576" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.576423576423576" /psig="0.972027972027972" /xcortree=3242 /SigmaFactorBS="gattttgcagaatgccgcaataggatagcggaacattttcgg ttctgaatgtccctcaaTTTGCTATTATATTTTTGTGataaattggaataaaatctca c" /listShort="pel" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 827925 /Source="Nicolas_upshifts" /id="U576" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.576423576423576" /psig="0.972027972027972" /xcortree=3242 /SigmaFactorBS="gattttgcagaatgccgcaataggatagcggaacattttcgg ttctgaatgtccctcaaTTTGCTATTATATTTTTGTGataaattggaataaaatctca c" /listShort="pel" /GFF_Attribute="listLong" CDS 827993..829255 /gene="pelA" /locus_tag="BSU_07560" /old_locus_tag="BSU07560" /EC_number="4.2.2.2" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:8262178, 12823818, 27447541" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8262178, 12823818, 27447541; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="pectate lyase" /protein_id="NP_388637.1" /db_xref="EnsemblGenomes-Gn:BSU07560" /db_xref="EnsemblGenomes-Tr:CAB12585" /db_xref="GOA:P39116" /db_xref="InterPro:IPR002022" /db_xref="InterPro:IPR011050" /db_xref="InterPro:IPR012334" /db_xref="PDB:1BN8" /db_xref="PDB:2BSP" /db_xref="PDB:2NZM" /db_xref="PDB:2O04" /db_xref="PDB:2O0V" /db_xref="PDB:2O0W" /db_xref="PDB:2O17" /db_xref="PDB:2O1D" /db_xref="PDB:3KRG" /db_xref="PDB:5AMV" /db_xref="SubtiList:BG10840" /db_xref="UniProtKB/Swiss-Prot:P39116" /translation="MKKVMLATALFLGLTPAGANAADLGHQTLGSNDGWGAYSTGTTG GSKASSSNVYTVSNRNQLVSALGKETNTTPKIIYIKGTIDMNVDDNLKPLGLNDYKDP EYDLDKYLKAYDPSTWGKKEPSGTQEEARARSQKNQKARVMVDIPANTTIVGSGTNAK VVGGNFQIKSDNVIIRNIEFQDAYDYFPQWDPTDGSSGNWNSQYDNITINGGTHIWID HCTFNDGSRPDSTSPKYYGRKYQHHDGQTDASNGANYITMSYNYYHDHDKSSIFGSSD SKTSDDGKLKITLHHNRYKNIVQRAPRVRFGQVHVYNNYYEGSTSSSSYPFSYAWGIG KSSKIYAQNNVIDVPGLSAAKTISVFSGGTALYDSGTLLNGTQINASAANGLSSSVGW TPSLHGSIDASANVKSNVINQAGAGKLN*" gene 827993..829255 /gene="pelA" /locus_tag="BSU_07560" /old_locus_tag="BSU07560" downshifts 829250 /Source="Nicolas_upshifts" /id="D377" /incds=0 /nref=139 /ntot=203 /MaxReadThrough="3.61256" /MaxDrop="5.92635" /score="1.82127533" /energy="-8.2" /TU="U575,U576" /idTUdmin="U576" /TUdmin="-176" /isTUend="FALSE" promotor_-35 829308..829311 /Source="Nicolas_upshift_promotors" /id="U577" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.879120879120879" /psig="0.984015984015984" /xcortree=1756 /SigmaFactorBS="gggtgctaacctttgtgttttttaattaattaaaATGTttat taacttagttAAGGAGTAGAATGGAAAAGGggatcggaaaacaagtatataggaggag a" /listShort="yflS" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 829326..829345 /Source="Nicolas_upshift_promotors" /id="U577" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.879120879120879" /psig="0.984015984015984" /xcortree=1756 /SigmaFactorBS="gggtgctaacctttgtgttttttaattaattaaaATGTttat taacttagttAAGGAGTAGAATGGAAAAGGggatcggaaaacaagtatataggaggag a" /listShort="yflS" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 829334 /Source="Nicolas_upshifts" /id="U577" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.879120879120879" /psig="0.984015984015984" /xcortree=1756 /SigmaFactorBS="gggtgctaacctttgtgttttttaattaattaaaATGTttat taacttagttAAGGAGTAGAATGGAAAAGGggatcggaaaacaagtatataggaggag a" /listShort="yflS" /GFF_Attribute="listLong" CDS 829382..830818 /gene="maeS" /locus_tag="BSU_07570" /old_locus_tag="BSU07570" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:12949159, 15849754, 16850406, 25651892, 28436820" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12949159, 15849754, 16850406, 25651892, 28436820; Product type t : transporter" /codon_start=1 /transl_table=11 /product="malate (2-oxoglutarate) transporter" /protein_id="NP_388638.1" /db_xref="EnsemblGenomes-Gn:BSU07570" /db_xref="EnsemblGenomes-Tr:CAB12586" /db_xref="GOA:O34726" /db_xref="InterPro:IPR001898" /db_xref="InterPro:IPR030676" /db_xref="SubtiList:BG12951" /db_xref="UniProtKB/Swiss-Prot:O34726" /translation="MASEKDAGKQSAVKLVPLLITVAVGLIIWFIPAPSGLEPKAWHL FAIFVATIIGFISKPLPMGAIAIFALAVTALTGTLSIEDTLSGFGNKTIWLIVIAFFI SRGFIKTGLGARISYVFVQKFGKKTLGLSYSLLFSDLILSPAIPSNTARAGGIIFPII RSLSETFGSSPANGTERKIGAFLLKTGFQGNLITSAMFLTAMAANPLIAKLAHDVAGV DLTWTSWAIAAIVPGLVSLIITPLVIYKLYPPEIKETPDAAKIATEKLKEMGPFKKSE LSMVIVFLLVLVLWIFGGSFNIDATTTALIGLAVLLLSQVLTWDDIKKEQGAWDTLTW FAALVMLANFLNELGMVSWFSNAMKSSVSGFSWIVAFIILIVVYYYSHYFFASATAHI SAMYSAFLAVVVAAGAPPLLAALSLAFISNLFGSTTHYGSGAAPVFFGAGYIPQGKWW SIGFILSIVHIIVWLVIGGLWWKVLGIW*" gene 829382..830818 /gene="maeS" /locus_tag="BSU_07570" /old_locus_tag="BSU07570" downshifts 830810 /Source="Nicolas_upshifts" /id="D378" /incds=0 /nref=56 /ntot=132 /MaxReadThrough="2.39993" /MaxDrop="5.36125" /score="40.3051497" /energy="-9.7" /TU="NA" /idTUdmin="U577" /TUdmin="-2" /isTUend="TRUE" misc_feature 830909..830928 /Source="Nicolas_upshift_promotors" /id="U578" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.997002997002997" /psig=1 /xcortree=2939 /SigmaFactorBS="tccttcgtaagaaaatggattttgaaaaatgagaaaattccc tgtgaaaAATGGTATGATCTAGGTAGAaaggacggctggtgctgtggtgaaaaagcgg t" /listShort="citS, citT, yflP" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 830920 /Source="Nicolas_upshifts" /id="U578" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.997002997002997" /psig=1 /xcortree=2939 /SigmaFactorBS="tccttcgtaagaaaatggattttgaaaaatgagaaaattccc tgtgaaaAATGGTATGATCTAGGTAGAaaggacggctggtgctgtggtgaaaaagcgg t" /listShort="citS, citT, yflP" /GFF_Attribute="listLong" CDS 830945..832573 /gene="citS" /locus_tag="BSU_07580" /old_locus_tag="BSU07580" /function="16.12: Sense" /experiment="publication(s) with functional evidences, PMID:10972810, 11717295, 12949159, 16842348" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10972810, 11717295, 12949159, 16842348; Product type rc: receptor" /codon_start=1 /transl_table=11 /product="two-component sensor histidine kinase" /protein_id="NP_388639.1" /db_xref="EnsemblGenomes-Gn:BSU07580" /db_xref="EnsemblGenomes-Tr:CAB12587" /db_xref="GOA:O34427" /db_xref="InterPro:IPR003594" /db_xref="InterPro:IPR004358" /db_xref="InterPro:IPR005467" /db_xref="InterPro:IPR016120" /db_xref="InterPro:IPR029151" /db_xref="InterPro:IPR035965" /db_xref="InterPro:IPR036890" /db_xref="SubtiList:BG12576" /db_xref="UniProtKB/Swiss-Prot:O34427" /translation="MVKKRFHFSLQTKIMGLIAALLVFVIGVLTITLAVQHTQGERRQ AEQLAVQTARTISYMPPVKELIERKDGHAAQTQEVIEQMKEQTGAFAIYVLNEKGDIR SASGKSGLKKLERSREILFGGSHVSETKADGRRVIRGSAPIIKEQKGYSQVIGSVSVD FLQTETEQSIKKHLRNLSVIAVLVLLLGFIGAAVLAKSIRKDTLGLEPHEIAALYRER NAMLFAIREGIIATNREGVVTMMNVSAAEMLKLPEPVIHLPIDDVMPGAGLMSVLEKG EMLPNQEVSVNDQVFIINTKVMNQGGQAYGIVVSFREKTELKKLIDTLTEVRKYSEDL RAQTHEFSNKLYAILGLLELGEYDEAIDLIKEEYAIQNEQHDLLFHNIHSQQVQAILL GKISKASEKKVKLVIDENSSLAPLPAHIGLSHLITIIGNLIDNAFEAVAEQSVKEVLF FITDMGHDIVIEVSDTGPGVPPEKIEAVFERGYSSKGMRRGYGLANVKDSVRELGGWI ELANQKTGGAVFTVFIPKEKQRGNPFDSHRDCGG*" gene 830945..832573 /gene="citS" /locus_tag="BSU_07580" /old_locus_tag="BSU07580" CDS 832545..833225 /gene="citT" /locus_tag="BSU_07590" /old_locus_tag="BSU07590" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:10972810, 11717295, 12949159, 16842348" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10972810, 11717295, 12949159, 16842348; Product type r: regulator" /codon_start=1 /transl_table=11 /product="two-component response regulator" /protein_id="NP_388640.1" /db_xref="EnsemblGenomes-Gn:BSU07590" /db_xref="EnsemblGenomes-Tr:CAB12588" /db_xref="GOA:O34534" /db_xref="InterPro:IPR001789" /db_xref="InterPro:IPR011006" /db_xref="InterPro:IPR013196" /db_xref="InterPro:IPR024187" /db_xref="InterPro:IPR028141" /db_xref="InterPro:IPR036388" /db_xref="SubtiList:BG12577" /db_xref="UniProtKB/Swiss-Prot:O34534" /translation="MIHIAIAEDDFRVAQIHERLIKQLDGFKIIGKAANAKETLALLK EHKADLLLLDIYMPDELGTALIPDIRSRFPEVDIMIITAATETRHLQEALRAGIAHYL IKPVTADKFRQVLLQYKEKRKLLMSQPEVSQSMIDHIFGNGVKTALPAEDLPTGINSI TLRKIKEALQTASEGLTAEELGEKMGASRTTARRYAEYLVSKEEARAELEYGIIGRPE RKYYLAAD*" gene 832545..833225 /gene="citT" /locus_tag="BSU_07590" /old_locus_tag="BSU07590" CDS 833228..834187 /gene="yflP" /locus_tag="BSU_07600" /old_locus_tag="BSU07600" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 11029430; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative tricarboxylate transporter component" /protein_id="NP_388641.2" /db_xref="EnsemblGenomes-Gn:BSU07600" /db_xref="EnsemblGenomes-Tr:CAB12589" /db_xref="GOA:O34439" /db_xref="InterPro:IPR005064" /db_xref="SubtiList:BG12950" /db_xref="UniProtKB/Swiss-Prot:O34439" /translation="MKKSIILLNILLIFMQGDIRQAAAPRLPDGPIEIVVPAEPSGGW DVTAQAIQSVLRQKQIVKDDVHIVYKSGGGGEKGWKYVNKSSKQTISMTSSLILSNDL LGQSKLKMSDFTPLAILSKEWQTVALPKGSALTNGKDVLNEINMHPGKVRIGFAPGFG NDDQLSFVRAADMYGIDPFDIQFSQYDSSEQLIQALIRHEIEAASMTLSEAKPYERNG DITLAAVTSDKRLPGFPNVPTWKEQGIPFVFSHWRGILGPKNMSEEEISYWDQALKKV TSSPEWKRKINEQDWESFYLNSRETKRFLEEQSAFYQSIMTGN*" gene 833228..834187 /gene="yflP" /locus_tag="BSU_07600" /old_locus_tag="BSU07600" downshifts 834156 /Source="Nicolas_upshifts" /id="D379" /incds=0 /nref=76 /ntot=211 /MaxReadThrough="1.1681" /MaxDrop="6.31244" /score="10.4510496" /energy="-6.5" /TU="NA" /idTUdmin="U578" /TUdmin=0 /isTUend="TRUE" promotor_-35 834279..834286 /Source="Nicolas_upshift_promotors" /id="U579" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.606393606393606" /psig="0.96003996003996" /xcortree=565 /SigmaFactorBS="aaaaaattaaaaatacaaaaaaaccaaatTATTTACTtgcgg ttggtttTCCCATACGATGGCAAAAAGgcaagacaaaaaggggagtaagggagaaaaa a" /listShort="S262, citM" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 834299..834318 /Source="Nicolas_upshift_promotors" /id="U579" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.606393606393606" /psig="0.96003996003996" /xcortree=565 /SigmaFactorBS="aaaaaattaaaaatacaaaaaaaccaaatTATTTACTtgcgg ttggtttTCCCATACGATGGCAAAAAGgcaagacaaaaaggggagtaagggagaaaaa a" /listShort="S262, citM" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 834310..834382 /Source="Nicolas_S_feature" /locus_tag="new_834310_834382" /HighExp="M9-stat, SMMPr, SMM, T0.0H, LoTm, T1.0H, Pyr, T1.30H, Cold, T2.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.96" /TUlongSig="NA" /TUlongPSig="NA" /label="S262" upshifts 834310 /Source="Nicolas_upshifts" /id="U579" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.606393606393606" /psig="0.96003996003996" /xcortree=565 /SigmaFactorBS="aaaaaattaaaaatacaaaaaaaccaaatTATTTACTtgcgg ttggtttTCCCATACGATGGCAAAAAGgcaagacaaaaaggggagtaagggagaaaaa a" /listShort="S262, citM" /GFF_Attribute="listLong" CDS 834383..835684 /gene="citM" /locus_tag="BSU_07610" /old_locus_tag="BSU07610" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:12427932, 12533460, 12906362, 12949159, 15849754, 16842348, 16850406, 24415722, 22720735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12427932, 12533460, 12906362, 12949159, 15849754, 16842348, 16850406, 24415722, 22720735; Product type t: transporter" /codon_start=1 /transl_table=11 /product="transporter of divalent metal ions/citrate complexes" /protein_id="NP_388642.1" /db_xref="EnsemblGenomes-Gn:BSU07610" /db_xref="EnsemblGenomes-Tr:CAB12590" /db_xref="GOA:P55069" /db_xref="InterPro:IPR004680" /db_xref="InterPro:IPR014738" /db_xref="SubtiList:BG11832" /db_xref="UniProtKB/Swiss-Prot:P55069" /translation="MLAILGFLMMLVFMALIMTKRLSVLTALVLTPIVFALIAGFGFT EVGDMMISGIQQVAPTAVMIMFAILYFGIMIDTGLFDPMVGKILSMVKGDPLKIVVGT AVLTMLVALDGDGSTTYMITTSAMLPLYLLLGIRPIILAGIAGVGMGIMNTIPWGGAT PRAASALGVDPAELTGPMIPVIASGMLCMVAVAYVLGKAERKRLGVIELKQPANANEP AAAVEDEWKRPKLWWFNLLLTLSLIGCLVSGKVSLTVLFVIAFCIALIVNYPNLEHQR QRIAAHSSNVLAIGSMIFAAGVFTGILTGTKMVDEMAISLVSMIPEQMGGLIPAIVAL TSGIFTFLMPNDAYFYGVLPILSETAVAYGVDKVEIARASIIGQPIHMLSPLVPSTHL LVGLVGVSIDDHQKFALKWAVLAVIVMTAIALLIGAISISV*" gene 834383..835684 /gene="citM" /locus_tag="BSU_07610" /old_locus_tag="BSU07610" promotor_-35 835681..835687 /Source="Nicolas_upshift_promotors" /id="U580" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=920 /SigmaFactorBS="ggctatcgctctattgatcggtgcgatctctatttccgtATG ATAAttcaggcgtaatgACACACACTAACggcatacaacattccggaggtgtcattat g" /listShort="yflN" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 835701..835712 /Source="Nicolas_upshift_promotors" /id="U580" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=920 /SigmaFactorBS="ggctatcgctctattgatcggtgcgatctctatttccgtATG ATAAttcaggcgtaatgACACACACTAACggcatacaacattccggaggtgtcattat g" /listShort="yflN" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 835702 /Source="Nicolas_upshifts" /id="U580" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=920 /SigmaFactorBS="ggctatcgctctattgatcggtgcgatctctatttccgtATG ATAAttcaggcgtaatgACACACACTAACggcatacaacattccggaggtgtcattat g" /listShort="yflN" /GFF_Attribute="listLong" CDS 835740..836534 /gene="yflN" /locus_tag="BSU_07620" /old_locus_tag="BSU07620" /EC_number="3.-.-.-" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 10972810, 22720735; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative metal-dependent hydrolase" /protein_id="NP_388643.1" /db_xref="EnsemblGenomes-Gn:BSU07620" /db_xref="EnsemblGenomes-Tr:CAB12591" /db_xref="GOA:O34409" /db_xref="InterPro:IPR001279" /db_xref="InterPro:IPR036866" /db_xref="SubtiList:BG12949" /db_xref="UniProtKB/Swiss-Prot:O34409" /translation="MSDPYMPLTSVRSGAGFEAAKGVHGLTVQIANVYFIQLPSEPHS FVLIDAGMPQSAGVIVNEAKQRFGEGFQLKAIILTHGHFDHIGAIEEILEHWDVPVYI HSREMPYVTGKEDYPPARPDSKSGLVAKLSPLFPRHSIDISSHVQALPEDGSVPFLDE WMWIATPGHTPGHISLFRDDGRVLVAGDAVITVEQEKMADVLIQKQELHGPPAYFTPD TETAAESILKLAGLEPEALLTGHGIPMTGKNFRSDLTELANRLSSI*" gene 835740..836534 /gene="yflN" /locus_tag="BSU_07620" /old_locus_tag="BSU07620" downshifts 836510 /Source="Nicolas_upshifts" /id="D380" /incds=0 /nref=2 /ntot=25 /MaxReadThrough="0.0114999999999998" /MaxDrop="3.05232" /score="38.3109333" /energy="-11.8" /TU="NA" /idTUdmin="U580" /TUdmin=132 /isTUend="FALSE" promotor_-35 836589..836592 /Source="Nicolas_upshift_promotors" /id="U581" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.509490509490509" /psig="0.995004995004995" /xcortree=2378 /SigmaFactorBS="attgttttccaggaagttgcagaaaaatcATTTgtcttgccg cttaaAAACGATACAATGAAAAGCAtgaagtgatgtgaaggggagagtttgttggaag a" /listShort="nosA, S263, yflK" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 836607..836626 /Source="Nicolas_upshift_promotors" /id="U581" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.509490509490509" /psig="0.995004995004995" /xcortree=2378 /SigmaFactorBS="attgttttccaggaagttgcagaaaaatcATTTgtcttgccg cttaaAAACGATACAATGAAAAGCAtgaagtgatgtgaaggggagagtttgttggaag a" /listShort="nosA, S263, yflK" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 836620 /Source="Nicolas_upshifts" /id="U581" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.509490509490509" /psig="0.995004995004995" /xcortree=2378 /SigmaFactorBS="attgttttccaggaagttgcagaaaaatcATTTgtcttgccg cttaaAAACGATACAATGAAAAGCAtgaagtgatgtgaaggggagagtttgttggaag a" /listShort="nosA, S263, yflK" /GFF_Attribute="listLong" CDS 836653..837744 /gene="nosA" /locus_tag="BSU_07630" /old_locus_tag="BSU07630" /EC_number="1.14.13.39" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:11856757, 12220171, 16172391, 25643072, 25826316, 26062720" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11856757, 12220171, 16172391, 25643072, 25826316, 26062720; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="nitric-oxide synthase" /protein_id="NP_388644.2" /db_xref="EnsemblGenomes-Gn:BSU07630" /db_xref="EnsemblGenomes-Tr:CAB12592" /db_xref="GOA:O34453" /db_xref="InterPro:IPR004030" /db_xref="InterPro:IPR017142" /db_xref="InterPro:IPR036119" /db_xref="PDB:1M7V" /db_xref="PDB:1M7Z" /db_xref="PDB:2AMO" /db_xref="PDB:2AN0" /db_xref="PDB:2AN2" /db_xref="PDB:2FBZ" /db_xref="PDB:2FC1" /db_xref="PDB:2FC2" /db_xref="PDB:4D3I" /db_xref="PDB:4D3J" /db_xref="PDB:4D3K" /db_xref="PDB:4D3M" /db_xref="PDB:4D3N" /db_xref="PDB:4D3O" /db_xref="PDB:4D3T" /db_xref="PDB:4D3U" /db_xref="PDB:4D3V" /db_xref="PDB:4D7H" /db_xref="PDB:4D7I" /db_xref="PDB:4D7J" /db_xref="PDB:4LWA" /db_xref="PDB:4LWB" /db_xref="PDB:4UG5" /db_xref="PDB:4UG6" /db_xref="PDB:4UG7" /db_xref="PDB:4UG8" /db_xref="PDB:4UG9" /db_xref="PDB:4UGA" /db_xref="PDB:4UGB" /db_xref="PDB:4UGC" /db_xref="PDB:4UGD" /db_xref="PDB:4UGE" /db_xref="PDB:4UGF" /db_xref="PDB:4UGG" /db_xref="PDB:4UGH" /db_xref="PDB:4UGI" /db_xref="PDB:4UGJ" /db_xref="PDB:4UGK" /db_xref="PDB:4UGL" /db_xref="PDB:4UGM" /db_xref="PDB:4UGN" /db_xref="PDB:4UGO" /db_xref="PDB:4UGP" /db_xref="PDB:4UGQ" /db_xref="PDB:4UGR" /db_xref="PDB:4UGS" /db_xref="PDB:4UGT" /db_xref="PDB:4UGU" /db_xref="PDB:4UGV" /db_xref="PDB:4UGW" /db_xref="PDB:4UGX" /db_xref="PDB:4UGY" /db_xref="PDB:4UQR" /db_xref="PDB:4UQS" /db_xref="PDB:5G65" /db_xref="PDB:5G66" /db_xref="PDB:5G67" /db_xref="PDB:5G68" /db_xref="PDB:5G69" /db_xref="PDB:5G6A" /db_xref="PDB:5G6B" /db_xref="PDB:5G6C" /db_xref="PDB:5G6D" /db_xref="PDB:5G6E" /db_xref="PDB:5G6F" /db_xref="PDB:5G6G" /db_xref="PDB:5G6H" /db_xref="PDB:5G6I" /db_xref="PDB:5G6J" /db_xref="PDB:5G6K" /db_xref="PDB:5G6L" /db_xref="PDB:5G6M" /db_xref="PDB:5G6N" /db_xref="PDB:5G6O" /db_xref="PDB:5G6P" /db_xref="PDB:5G6Q" /db_xref="SubtiList:BG12948" /db_xref="UniProtKB/Swiss-Prot:O34453" /translation="MEEKEILWNEAKAFIAACYQELGKEEEVKDRLADIKSEIDLTGS YVHTKEELEHGAKMAWRNSNRCIGRLFWNSLNVIDRRDVRTKEEVRDALFHHIETATN NGKIRPTITIFPPEEKGEKQVEIWNHQLIRYAGYESDGERIGDPASCSLTAACEELGW RGERTDFDLLPLIFRMKGDEQPVWYELPRSLVIEVPITHPDIEAFSDLELKWYGVPII SDMKLEVGGIHYNAAPFNGWYMGTEIGARNLADEKRYDKLKKVASVIGIAADYNTDLW KDQALVELNKAVLHSYKKQGVSIVDHHTAASQFKRFEEQEEEAGRKLTGDWTWLIPPI SPAATHIFHRSYDNSIVKPNYFYQDKPYE*" gene 836653..837744 /gene="nosA" /locus_tag="BSU_07630" /old_locus_tag="BSU07630" CDS complement(837735..838010) /gene="acyP" /locus_tag="BSU_07640" /old_locus_tag="BSU07640" /EC_number="3.6.1.7" /function="16.11: Scavenge (Catabolism)" /function="16.8: Protect" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:20447399" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 20447399; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="acylphosphatase" /protein_id="NP_388645.1" /db_xref="EnsemblGenomes-Gn:BSU07640" /db_xref="EnsemblGenomes-Tr:CAB12593" /db_xref="GOA:O35031" /db_xref="InterPro:IPR001792" /db_xref="InterPro:IPR017968" /db_xref="InterPro:IPR020456" /db_xref="InterPro:IPR036046" /db_xref="PDB:2FHM" /db_xref="PDB:2HLT" /db_xref="PDB:2HLU" /db_xref="PDB:3BR8" /db_xref="SubtiList:BG12947" /db_xref="UniProtKB/Swiss-Prot:O35031" /translation="MLQYRIIVDGRVQGVGFRYFVQMEADKRKLAGWVKNRDDGRVEI LAEGPENALQSFVEAVKNGSPFSKVTDISVTESRSLEGHHRFSIVYS*" gene complement(837735..838010) /gene="acyP" /locus_tag="BSU_07640" /old_locus_tag="BSU07640" S_feature 837745..838076 /Source="Nicolas_S_feature" /locus_tag="new_837745_838076" /HighExp="C90, BI, Paraq, LBGexp, Oxctl, M0t45, G150, M40t45, G135, H2O2" /AntisenseName="yflL" /AntisenseCor="0.38657275217332299" /AntisenseRegPval="-10.3" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.995" /TUlongSig="NA" /TUlongPSig="NA" /label="S263" promotor_-10 complement(838024..838043) /Source="Nicolas_upshift_promotors" /id="U582" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.818181818181818" /psig="0.998001998001998" /xcortree=3152 /SigmaFactorBS="ctgaatagcgctcttgtttcatacaaacacatcCCCTTTACa ggttgtaaaatgaTTGATTATCATAAAAAGAAAaggtggtttttacatgcttcaatac c" /listShort="yflL" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(838038) /Source="Nicolas_upshifts" /id="U582" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.818181818181818" /psig="0.998001998001998" /xcortree=3152 /SigmaFactorBS="ctgaatagcgctcttgtttcatacaaacacatcCCCTTTACa ggttgtaaaatgaTTGATTATCATAAAAAGAAAaggtggtttttacatgcttcaatac c" /listShort="yflL" /GFF_Attribute="listLong" promotor_-35 complement(838058..838065) /Source="Nicolas_upshift_promotors" /id="U582" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.818181818181818" /psig="0.998001998001998" /xcortree=3152 /SigmaFactorBS="ctgaatagcgctcttgtttcatacaaacacatcCCCTTTACa ggttgtaaaatgaTTGATTATCATAAAAAGAAAaggtggtttttacatgcttcaatac c" /listShort="yflL" /GFF_Attribute="listLong" /label="promotor_-35" CDS 838077..838742 /gene="yflK" /locus_tag="BSU_07650" /old_locus_tag="BSU07650" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 11886751; Product type c: carrier" /codon_start=1 /transl_table=11 /product="putative sulfur carrier" /protein_id="NP_388646.1" /db_xref="EnsemblGenomes-Gn:BSU07650" /db_xref="EnsemblGenomes-Tr:CAB12594" /db_xref="GOA:O34542" /db_xref="InterPro:IPR005163" /db_xref="InterPro:IPR005302" /db_xref="InterPro:IPR011037" /db_xref="SubtiList:BG12946" /db_xref="UniProtKB/Swiss-Prot:O34542" /translation="MKQERYSVLSLNLGKPQTLEYDGKKIETGIMKRPAKSAVMLYRE NFEGDGQADLVNHGGPDKAVCVYPAEHYPFWEEFLSRPLSNAAFGENLTVAGLTEENV CIGDVFRLDEAVVQVSQPRQPCVKLAKKFGVKEMVLKVQQTGYTGFYFRVLEEGRVSP GANLELLSRGEKGISVQFANRINYHDAKNLTAIERILSEAALSESWRASFMKKKDRLL PVE*" gene 838077..838742 /gene="yflK" /locus_tag="BSU_07650" /old_locus_tag="BSU07650" CDS complement(838783..838920) /gene="yflJ" /locus_tag="BSU_07660" /old_locus_tag="BSU07660" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_388647.1" /db_xref="EnsemblGenomes-Gn:BSU07660" /db_xref="EnsemblGenomes-Tr:CAB12595" /db_xref="InterPro:IPR022580" /db_xref="SubtiList:BG12945" /db_xref="UniProtKB/Swiss-Prot:O34345" /translation="MHYGSKGWYVAELKKQGITHHEGRKLQSYKTYFLANLLESKKKQ S*" gene complement(838783..838920) /gene="yflJ" /locus_tag="BSU_07660" /old_locus_tag="BSU07660" downshifts complement(838797) /Source="Nicolas_upshifts" /id="D381" /incds=0 /nref=136 /ntot=260 /MaxReadThrough="0.0927600000000002" /MaxDrop="8.10929" /score="29.8336543" /energy="-14.8" /TU="NA" /idTUdmin="U583" /TUdmin="-11" /isTUend="TRUE" S_feature complement(838921..839051) /Source="Nicolas_S_feature" /locus_tag="new_838921_839051_c" /HighExp="S4, S7, S8, S6, S5, S3, B36, BT, LoTm, B60" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigEF, SigA" /TUshortPSig="0.967, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S264" promotor_-10 complement(839037..839055) /Source="Nicolas_upshift_promotors" /id="U583" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.967032967032967" /psig="0.967032967032967" /xcortree=1134 /SigmaFactorBS="ttggcgttgtcatgatcaaactaaccggccattaaATCATAt tcggcttttgctccGCATATACATTCAGAAGAAcattcgtacatctagtgcgaaaggc t" /listShort="S264, yflJ" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 839047..839052 /Source="Nicolas_upshift_promotors" /id="U584" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1109 /SigmaFactorBS="gaaaactgagcctttcgcactagatgtacgaatgttcttctg aaTGTATAtgcggagcaaaagccGAATATGATTTAATGGCCGgttagtttgatcatga c" /listShort="S265" /GFF_Attribute="listLong" /label="promotor_-35" upshifts complement(839051) /Source="Nicolas_upshifts" /id="U583" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.967032967032967" /psig="0.967032967032967" /xcortree=1134 /SigmaFactorBS="ttggcgttgtcatgatcaaactaaccggccattaaATCATAt tcggcttttgctccGCATATACATTCAGAAGAAcattcgtacatctagtgcgaaaggc t" /listShort="S264, yflJ" /GFF_Attribute="listLong" S_feature 839062..840126 /Source="Nicolas_S_feature" /locus_tag="new_839062_840126" /HighExp="S8, S6, S5, S7, S4, S3, BT, B36, C90, T5.0H" /AntisenseName="mapB" /AntisenseCor="-0.26446079057314398" /AntisenseRegPval="-5" /CDS_PredictionProba="NA" /TUshortSig="SigEF" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S265" upshifts 839063 /Source="Nicolas_upshifts" /id="U584" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1109 /SigmaFactorBS="gaaaactgagcctttcgcactagatgtacgaatgttcttctg aaTGTATAtgcggagcaaaagccGAATATGATTTAATGGCCGgttagtttgatcatga c" /listShort="S265" /GFF_Attribute="listLong" promotor_-10 839068..839086 /Source="Nicolas_upshift_promotors" /id="U584" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1109 /SigmaFactorBS="gaaaactgagcctttcgcactagatgtacgaatgttcttctg aaTGTATAtgcggagcaaaagccGAATATGATTTAATGGCCGgttagtttgatcatga c" /listShort="S265" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 complement(839071..839076) /Source="Nicolas_upshift_promotors" /id="U583" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.967032967032967" /psig="0.967032967032967" /xcortree=1134 /SigmaFactorBS="ttggcgttgtcatgatcaaactaaccggccattaaATCATAt tcggcttttgctccGCATATACATTCAGAAGAAcattcgtacatctagtgcgaaaggc t" /listShort="S264, yflJ" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(839077..839232) /gene="yflI" /locus_tag="BSU_07670" /old_locus_tag="BSU07670" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved membrane protein" /protein_id="NP_388648.1" /db_xref="EnsemblGenomes-Gn:BSU07670" /db_xref="EnsemblGenomes-Tr:CAB12596" /db_xref="GOA:O34905" /db_xref="SubtiList:BG12944" /db_xref="UniProtKB/Swiss-Prot:O34905" /translation="MWFIIFGIIFFIEGIIMTVYGVKKKNGMLTYIGIVFAIMTFGVV MIKLTGH*" gene complement(839077..839232) /gene="yflI" /locus_tag="BSU_07670" /old_locus_tag="BSU07670" S_feature complement(839233..839338) /Source="Nicolas_S_feature" /locus_tag="new_839233_839338_c" /HighExp="Etha, Salt, Diami, dia15, H2O2, Cold, G135, Paraq, LPhT, G150" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S266" CDS complement(839339..839653) /gene="yflH" /locus_tag="BSU_07680" /old_locus_tag="BSU07680" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 1070366, 1266368; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative enzyme" /protein_id="NP_388649.1" /db_xref="EnsemblGenomes-Gn:BSU07680" /db_xref="EnsemblGenomes-Tr:CAB12597" /db_xref="InterPro:IPR021637" /db_xref="PDB:3D0W" /db_xref="SubtiList:BG12943" /db_xref="UniProtKB/Swiss-Prot:O34306" /translation="MNRDQEKIQIENEMNAMHGTIKEDILKDFEEFKGYLKKQVNRGK KLGLDDGKLVKSAAILGDYLAKHEEPQNGEEMLLQELWSVADEDEKEHLAQLLVKLVD KQ*" gene complement(839339..839653) /gene="yflH" /locus_tag="BSU_07680" /old_locus_tag="BSU07680" S_feature complement(839654..839734) /Source="Nicolas_S_feature" /locus_tag="new_839654_839734_c" /HighExp="dia5, dia15, Diami, LBGtran, LPhT, H2O2, Etha, Lbtran, M40t45, M40t90" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigK" /TUshortPSig="1, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S267" CDS complement(839735..840484) /gene="mapB" /locus_tag="BSU_07690" /old_locus_tag="BSU07690" /EC_number="3.4.11.18" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:16207374" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16207374; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="methionine aminopeptidase B" /protein_id="NP_388650.1" /db_xref="EnsemblGenomes-Gn:BSU07690" /db_xref="EnsemblGenomes-Tr:CAB12598" /db_xref="GOA:O34484" /db_xref="InterPro:IPR000994" /db_xref="InterPro:IPR001714" /db_xref="InterPro:IPR002467" /db_xref="InterPro:IPR036005" /db_xref="SubtiList:BG12942" /db_xref="UniProtKB/Swiss-Prot:O34484" /translation="MIVTNDQELEGLKKIGRIVALAREEMKRKAEPGMSTKDLDLIGK AVLDEHGAVSAPEKEYDFPGVTCISVNDEVAHGIPSTSKILKAGDLVNIDISAEFGGF YSDTGISFVLGEGEERLHKLCQCAENAFQKGLQQAKAGKRQNQIGRAVYHEARSQGFT VIKTLTGHGIGRSLHEAPNHIMNYYDPFDNALFKNGTVIALEPFISTKAETIVEAGDG WTFKTPDKSMVAQVEHTIVITKDEPIILTKL*" gene complement(839735..840484) /gene="mapB" /locus_tag="BSU_07690" /old_locus_tag="BSU07690" promotor_-10 complement(840513..840532) /Source="Nicolas_upshift_promotors" /id="U585" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.786213786213786" /psig=1 /xcortree=1950 /SigmaFactorBS="cccgggggtatttcttttttcccaggtccgtgtgTTTCCTAT TtttaagacagtTGTGGTAAGCTTAATCTAGAttatttaaaaagaaagcgggaatgac a" /listShort="mapB, S267, yflH, S266, yflI, S264, yflJ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(840526) /Source="Nicolas_upshifts" /id="U585" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.786213786213786" /psig=1 /xcortree=1950 /SigmaFactorBS="cccgggggtatttcttttttcccaggtccgtgtgTTTCCTAT TtttaagacagtTGTGGTAAGCTTAATCTAGAttatttaaaaagaaagcgggaatgac a" /listShort="mapB, S267, yflH, S266, yflI, S264, yflJ" /GFF_Attribute="listLong" S_feature complement(840528..841664) /Source="Nicolas_S_feature" /locus_tag="new_840528_841664_c" /HighExp="S6, S8, S7, S5, BT, C30, Paraq, B36, G180, Pyr" /AntisenseName="nagP" /AntisenseCor="0.180776000778922" /AntisenseRegPval="-2.5" /CDS_PredictionProba="NA" /TUshortSig="SigK" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S268" promotor_-35 complement(840544..840552) /Source="Nicolas_upshift_promotors" /id="U585" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.786213786213786" /psig=1 /xcortree=1950 /SigmaFactorBS="cccgggggtatttcttttttcccaggtccgtgtgTTTCCTAT TtttaagacagtTGTGGTAAGCTTAATCTAGAttatttaaaaagaaagcgggaatgac a" /listShort="mapB, S267, yflH, S266, yflI, S264, yflJ" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 840595..840596 /Source="Nicolas_upshift_promotors" /id="U586" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.493506493506494" /psig="0.995004995004995" /xcortree=1559 /SigmaFactorBS="gacctgggaaaaaagaaatacccccgggaaaattggTAtaga tcactagatatcttaTATGGTATATTTGAAAAAAAagggtatgagggggatgggtatg c" /listShort="nagP" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 840616..840635 /Source="Nicolas_upshift_promotors" /id="U586" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.493506493506494" /psig="0.995004995004995" /xcortree=1559 /SigmaFactorBS="gacctgggaaaaaagaaatacccccgggaaaattggTAtaga tcactagatatcttaTATGGTATATTTGAAAAAAAagggtatgagggggatgggtatg c" /listShort="nagP" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 840619 /Source="Nicolas_upshifts" /id="U586" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.493506493506494" /psig="0.995004995004995" /xcortree=1559 /SigmaFactorBS="gacctgggaaaaaagaaatacccccgggaaaattggTAtaga tcactagatatcttaTATGGTATATTTGAAAAAAAagggtatgagggggatgggtatg c" /listShort="nagP" /GFF_Attribute="listLong" CDS 840656..842014 /gene="nagP" /locus_tag="BSU_07700" /old_locus_tag="BSU07700" /function="16.11: Scavenge (Catabolism)" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2b: Function from indirect experimental evidences (e.g. phenotypes); PubMedId: 15849754, 16850406, 8246840; Product type t: transporter" /codon_start=1 /transl_table=11 /product="phosphotransferase system (PTS) N-acetylglucosamine-specific enzyme IICB component" /protein_id="NP_388651.1" /db_xref="EnsemblGenomes-Gn:BSU07700" /db_xref="EnsemblGenomes-Tr:CAB12599" /db_xref="GOA:O34521" /db_xref="InterPro:IPR001996" /db_xref="InterPro:IPR003352" /db_xref="InterPro:IPR010974" /db_xref="InterPro:IPR013013" /db_xref="InterPro:IPR018113" /db_xref="InterPro:IPR036878" /db_xref="SubtiList:BG12941" /db_xref="UniProtKB/Swiss-Prot:O34521" /translation="MLSFLQKLGKSFMLPIAVLPAVGIILALGREDVFNIPFVYQAGT AVFDHLPLIFAIGIAIGISKDSNGAAGLSGAISYLMLDAATKTIDKTNNMAVFGGIIA GLIAGYTYNRFKDTKLPEYLGFFSGRRLVPILTAIITIILAGIFGVVWPPIQSCINSF GEWMLGLGGIGAGIFGLFNRLLIPLGLHHVLNNIFWFQFGEYNGVTGDLARFFAKDPT AGTYMTGFFPIMMFGLPAACLAMVVTAKPSKRKATAGMMIGFALTAFITGITEPIEFA FMFLSPLLYAVHAVLTGLSLFIVNWLGIRSGFSFSAGAIDYVLSYGIAEKPLLLLLVG ICYAAVYFIVFYVLIKALNLKTPGREDDDVDEVLDENTVQDVNENIMLKGLGGKENLQ TIDHCATRLRLTVKDTALVDEALLKKAGAKGVVKSGGQSVQVIIGPNVEFAAEELRAA VK*" gene 840656..842014 /gene="nagP" /locus_tag="BSU_07700" /old_locus_tag="BSU07700" promotor_-10 complement(841650..841669) /Source="Nicolas_upshift_promotors" /id="U587" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1378 /SigmaFactorBS="gcgtttttaaattcaaagccttaatcagtacaTAAAACACGA taaagtatactgcCGCATAGCATATACCTACCAaaagcagaagcagcggtttttccgc g" /listShort="S268, mapB, S267, yflH" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(841664) /Source="Nicolas_upshifts" /id="U587" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1378 /SigmaFactorBS="gcgtttttaaattcaaagccttaatcagtacaTAAAACACGA taaagtatactgcCGCATAGCATATACCTACCAaaagcagaagcagcggtttttccgc g" /listShort="S268, mapB, S267, yflH" /GFF_Attribute="listLong" promotor_-35 complement(841683..841692) /Source="Nicolas_upshift_promotors" /id="U587" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1378 /SigmaFactorBS="gcgtttttaaattcaaagccttaatcagtacaTAAAACACGA taaagtatactgcCGCATAGCATATACCTACCAaaagcagaagcagcggtttttccgc g" /listShort="S268, mapB, S267, yflH" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 841900 /Source="Nicolas_upshifts" /id="D382" /incds=1 /nref=1 /ntot=106 /MaxReadThrough="3.67421" /MaxDrop="3.12268" /score="44.7832762" /energy="-16.9" /TU="U586" /idTUdmin="U586" /TUdmin="-88" /isTUend="FALSE" downshifts 842010 /Source="Nicolas_upshifts" /id="D383" /incds=0 /nref=2 /ntot=87 /MaxReadThrough="2.54331" /MaxDrop="3.17508" /score="44.7832762" /energy="-16.9" /TU="NA" /idTUdmin="U586" /TUdmin=22 /isTUend="TRUE" CDS complement(842047..843996) /gene="ltaSB" /locus_tag="BSU_07710" /old_locus_tag="BSU07710" /function="16.1: Circulate" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:10658653, 21255105" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10658653, 21255105; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="enzyme responsible for polyglycerolphosphate LTAsynthesis" /protein_id="NP_388652.1" /db_xref="EnsemblGenomes-Gn:BSU07710" /db_xref="EnsemblGenomes-Tr:CAB12600" /db_xref="GOA:O34952" /db_xref="InterPro:IPR000917" /db_xref="InterPro:IPR012160" /db_xref="InterPro:IPR017849" /db_xref="InterPro:IPR017850" /db_xref="PDB:2W8D" /db_xref="SubtiList:BG12940" /db_xref="UniProtKB/Swiss-Prot:O34952" /translation="MKTFIKERGLAFFLIAVVLLWIKTYVGYVLNFNLGIDNTIQKIL LFVNPLSSSLFFLGFGLLFKKKLQQTAIIVIHFLMSFLLYANIVYYRFFNDFITIPVI MQAKTNGGQLGDSAFSLMRPTDAFYFIDTIILIILAIKVNKPAETSSKKSFRIIFASS ILVFLINLAVAESDRPELLTRSFDRNYLVKYLGTYNFTIYDAVQNIKSNSQRALADSS DVTEVENYMKANYDVPNNVYFGKAEGKNVIYVSLESLQSFIIDYKIDGKEVTPFLNKL AHDNETFYFDNFFHQTGQGKTSDAEFMMENSLYPLAQGSVFVNKAQNTLQSVPAILKS KNYTSATFHGNTQTFWNRNEMYKAEGIDKFFDSAYYDMNEENTKNYGMKDKPFFKESM PLLESLPQPFYTKFITLSNHFPFGMDEGDTDFPAGDFGDSVVDNYFQSAHYLDQSIEQ FFNDLKKDGLYDKSIIVMYGDHYGISENHNKAMAKVLGKDEITDYDNAQLQRVPLFIH AAGVKGEKVHKYAGDVDVAPTILHLLGVDTKDYLMSGSDILSKEHREVIPFRNGDFIS PKYTKISGKYYDTKTGKELDESEVDKSEDSLVKKELEMSDKIINGDLLRFYEPKGFKK VNPSDYDYTKHDEDSSETSKDNEDK*" gene complement(842047..843996) /gene="ltaSB" /locus_tag="BSU_07710" /old_locus_tag="BSU07710" downshifts complement(842064) /Source="Nicolas_upshifts" /id="D384" /incds=0 /nref=219 /ntot=250 /MaxReadThrough="1.71031" /MaxDrop="6.08461" /score="43.6427282" /energy="-15.9" /TU="NA" /idTUdmin="U589" /TUdmin=0 /isTUend="TRUE" promotor_-35 843106..843112 /Source="Nicolas_upshift_promotors" /id="U588" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=153 /SigmaFactorBS="acagagagttttccatcataaattcagcatcagaTGTTTTAc cttgtcccgtttggTGGAAAAAGTTATCAAAGTagaacgtttcgttatcatgtgccag t" /listShort="S269, yflD, yflB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 843128..843146 /Source="Nicolas_upshift_promotors" /id="U588" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=153 /SigmaFactorBS="acagagagttttccatcataaattcagcatcagaTGTTTTAc cttgtcccgtttggTGGAAAAAGTTATCAAAGTagaacgtttcgttatcatgtgccag t" /listShort="S269, yflD, yflB" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 843132..844096 /Source="Nicolas_S_feature" /locus_tag="new_843132_844096" /HighExp="Etha, Salt, Sw, Gly, C30, M9-stat, S8, B60, BC, S7" /AntisenseName="yflE" /AntisenseCor="-0.385555454026206" /AntisenseRegPval="-10.199999999999999" /CDS_PredictionProba="NA" /TUshortSig="SigB" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S269" upshifts 843132 /Source="Nicolas_upshifts" /id="U588" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=153 /SigmaFactorBS="acagagagttttccatcataaattcagcatcagaTGTTTTAc cttgtcccgtttggTGGAAAAAGTTATCAAAGTagaacgtttcgttatcatgtgccag t" /listShort="S269, yflD, yflB" /GFF_Attribute="listLong" S_feature complement(843997..844071) /Source="Nicolas_S_feature" /locus_tag="new_843997_844071_c" /HighExp="Paraq, H2O2, LBGexp, G150, G135, G180, Lbexp, C30, LPhT, BMM" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S270" promotor_-10 complement(844048..844067) /Source="Nicolas_upshift_promotors" /id="U589" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.956043956043956" /psig=1 /xcortree=2614 /SigmaFactorBS="gattcgacggcgtttttcgccactttctccctcatacgattt tcACTTTtctaatctgctgattCGTGTTATATTGGATACGTTcgttttttctatcgtt t" /listShort="S270, yflE" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(844071) /Source="Nicolas_upshifts" /id="U589" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.956043956043956" /psig=1 /xcortree=2614 /SigmaFactorBS="gattcgacggcgtttttcgccactttctccctcatacgattt tcACTTTtctaatctgctgattCGTGTTATATTGGATACGTTcgttttttctatcgtt t" /listShort="S270, yflE" /GFF_Attribute="listLong" S_feature complement(844073..844595) /Source="Nicolas_S_feature" /locus_tag="new_844073_844595_c" /HighExp="S3, LoTm, S7, S4, S5, S8, S6, M9-stat, C30, Pyr" /AntisenseName="yflD" /AntisenseCor="0.24383322556613099" /AntisenseRegPval="-4.3" /CDS_PredictionProba="NA" /TUshortSig="SigEF" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S271" promotor_-35 complement(844083..844087) /Source="Nicolas_upshift_promotors" /id="U589" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.956043956043956" /psig=1 /xcortree=2614 /SigmaFactorBS="gattcgacggcgtttttcgccactttctccctcatacgattt tcACTTTtctaatctgctgattCGTGTTATATTGGATACGTTcgttttttctatcgtt t" /listShort="S270, yflE" /GFF_Attribute="listLong" /label="promotor_-35" CDS 844097..844234 /gene="yflD" /locus_tag="BSU_07720" /old_locus_tag="BSU07720" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="NP_388653.1" /db_xref="EnsemblGenomes-Gn:BSU07720" /db_xref="EnsemblGenomes-Tr:CAB12601" /db_xref="SubtiList:BG12939" /db_xref="UniProtKB/Swiss-Prot:O34489" /translation="MREKVAKNAVESTFRFDITKCKTRYLSRNKGIKWYIENCMIKYK V*" gene 844097..844234 /gene="yflD" /locus_tag="BSU_07720" /old_locus_tag="BSU07720" upshifts 844212 /Source="Nicolas_upshifts" /id="U590" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.895104895104895" /psig="0.952047952047952" /xcortree=589 /SigmaFactorBS="ccaaatgtaaaacaaggtatctttctagaaataaaggaataa aatggtacattgagaattgTATGATAAAATATAAGGTATagataaaaagaggtgaaat g" /listShort="yflB" /listLong="yflA, S272" misc_feature 844213..844232 /Source="Nicolas_upshift_promotors" /id="U590" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.895104895104895" /psig="0.952047952047952" /xcortree=589 /SigmaFactorBS="ccaaatgtaaaacaaggtatctttctagaaataaaggaataa aatggtacattgagaattgTATGATAAAATATAAGGTATagataaaaagaggtgaaat g" /listShort="yflB" /listLong="yflA, S272" /label="promotor_single_box" /note="Geneious type: promotor_single_box" CDS 844253..844645 /gene="yflB" /locus_tag="BSU_07735" /old_locus_tag="BSU07735" /function="18: Unknown function" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_388655.2" /db_xref="EnsemblGenomes-Gn:BSU07735" /db_xref="EnsemblGenomes-Tr:CAB12603" /db_xref="InterPro:IPR018961" /db_xref="SubtiList:BG12937" /db_xref="UniProtKB/Swiss-Prot:O34887" /translation="MDFSHIVSEDKIKRAIKDGDFQNLPGMGKPLPKDDAAHLPESLR MGYRILKNAGMAEDEGALKKELMTIDHLIEKCYDEKEREQLIRKKSEKQLLLDKLVDK KGMFSKPASAFYKNKVYDRLGRNRPSSS*" gene 844253..844645 /gene="yflB" /locus_tag="BSU_07735" /old_locus_tag="BSU07735" promotor_-10 complement(844593..844611) /Source="Nicolas_upshift_promotors" /id="U591" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=999 /SigmaFactorBS="cgccatcctgcagacaagacaaatcagctggaagaaGGTCTG tttcgtccaagccggTCATATACTTTATTCTTATaaaaagcggatgctggctttgaaa a" /listShort="S271" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(844608) /Source="Nicolas_upshifts" /id="U591" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=999 /SigmaFactorBS="cgccatcctgcagacaagacaaatcagctggaagaaGGTCTG tttcgtccaagccggTCATATACTTTATTCTTATaaaaagcggatgctggctttgaaa a" /listShort="S271" /GFF_Attribute="listLong" promotor_-35 complement(844627..844632) /Source="Nicolas_upshift_promotors" /id="U591" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=999 /SigmaFactorBS="cgccatcctgcagacaagacaaatcagctggaagaaGGTCTG tttcgtccaagccggTCATATACTTTATTCTTATaaaaagcggatgctggctttgaaa a" /listShort="S271" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 844714..844720 /Source="Nicolas_upshift_promotors" /id="U592" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=234 /SigmaFactorBS="aaaagccatcctttttatgttccaagttctatgtcaaaaGGT TTATgtttttccatctatGGGAAATGATTCATAAACGaaaaaagggtgatgggatgga a" /listShort="yflA, S272" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 844735..844753 /Source="Nicolas_upshift_promotors" /id="U592" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=234 /SigmaFactorBS="aaaagccatcctttttatgttccaagttctatgtcaaaaGGT TTATgtttttccatctatGGGAAATGATTCATAAACGaaaaaagggtgatgggatgga a" /listShort="yflA, S272" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 844735 /Source="Nicolas_upshifts" /id="U592" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=234 /SigmaFactorBS="aaaagccatcctttttatgttccaagttctatgtcaaaaGGT TTATgtttttccatctatGGGAAATGATTCATAAACGaaaaaagggtgatgggatgga a" /listShort="yflA, S272" /GFF_Attribute="listLong" CDS 844770..846185 /gene="yflA" /locus_tag="BSU_07750" /old_locus_tag="BSU07750" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative aminoacid transporter" /protein_id="NP_388656.1" /db_xref="EnsemblGenomes-Gn:BSU07750" /db_xref="EnsemblGenomes-Tr:CAB12604" /db_xref="GOA:O34708" /db_xref="InterPro:IPR001463" /db_xref="SubtiList:BG12936" /db_xref="UniProtKB/Swiss-Prot:O34708" /translation="MERLLVWIEHISDWLWGPPLIILLTGTGLYFTILLKGFQFRYPL YIFKQTIGSVGKKPKGEGTVTPLQALTSALSSTIGAANIVGVPAAIMFGGPGAVFWMW LIALFAMAIKFSESVLAVHYREKNEQGEYVGGPMYYITKGLRMKWLGVFFSVALIVEL IPSIMVQGNSVSVSLAETFSFNKIYAGIGIAFLIGLVVIGGVKRIGKVTEFVVPLMAG AYAGAGLLIVLMNLSSVPAFFSLVFSNAFTSSSAVGGFAGAALAETVRWGFARGLYSN EAGMGTAPIAHAAAMTDHPVRQGFWSVIGIVIDTLIICTTTAFIVLASGVWTGKNASN DPAALTTAAFQHYFGSGGGYFVSVSLVFFVVSTIMVVIFYGVKQAEFLFGRLAGHVIK FVYLAAIIIGAAGGAKAIWGVLDLALVFIVVPNVIALLLLSRKVKALYTEFFTSEQYY LKDIRKTKQKPVYPTKEAKNS*" gene 844770..846185 /gene="yflA" /locus_tag="BSU_07750" /old_locus_tag="BSU07750" downshifts complement(844771) /Source="Nicolas_upshifts" /id="D385" /incds=0 /nref=4 /ntot=16 /MaxReadThrough="0.76492" /MaxDrop="4.20973" /score="43.6427282" /energy="-15.9" /TU="NA" /idTUdmin="U593" /TUdmin=22 /isTUend="TRUE" promotor_no_box complement(844797..844897) /Source="Nicolas_upshift_promotors" /id="U593" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.723276723276723" /psig="0.006993006993007" /xcortree=122 /SigmaFactorBS="ggatagcgaaattgaaaacctttcagcaaaatagtgaaatac aagcccgtccccgtcagcaggatgattagcggcggaccccacagccaatcagatatat g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_no_box" upshifts complement(844837) /Source="Nicolas_upshifts" /id="U593" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.723276723276723" /psig="0.006993006993007" /xcortree=122 /SigmaFactorBS="ggatagcgaaattgaaaacctttcagcaaaatagtgaaatac aagcccgtccccgtcagcaggatgattagcggcggaccccacagccaatcagatatat g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" CDS complement(846182..847258) /gene="yfkT" /locus_tag="BSU_07760" /old_locus_tag="BSU07760" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 10762253, 15849754, 16850406, 23625846; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative spore germination integral inner membrane transporter" /protein_id="NP_388657.1" /db_xref="EnsemblGenomes-Gn:BSU07760" /db_xref="EnsemblGenomes-Tr:CAB12605" /db_xref="GOA:O34573" /db_xref="InterPro:IPR004761" /db_xref="SubtiList:BG12935" /db_xref="UniProtKB/Swiss-Prot:O34573" /translation="MDKTSAYQGLFFGALYTLAVGLKHAPILMIESAKQNAWHSYILG VVIVIPALWLMHRLMKKHQDKNIYELLSDSSPIAGRIIILLFSLYFLLINAHDIRFFI NLINILFLPRTPMAVLGGVIIFVAICIAREGKETLTRMAQIFLFPFGILVLFLPFTLA TQIELQNLTPVFEGLIPYLQSGYYAFGTMGELIILPLLFSNRSVPLKYTIFAILLGAL LLAVMLFSSISVFGPNLTSTFFDPAYMVIRQIRITDFLDRSDLIIAAFWIPVIMVKIA GSLYIVVYGLSFLHSKIDPKAMYTPTGMFSVVCGFWFFLNTNQLIDFNRIKPIINVVI SLLLPLLIYLIIKSKALFGAKAKH*" gene complement(846182..847258) /gene="yfkT" /locus_tag="BSU_07760" /old_locus_tag="BSU07760" S_feature 846186..849552 /Source="Nicolas_S_feature" /locus_tag="new_846186_849552" /HighExp="Salt, Sw, Etha, LoTm, B36, Heat, LPhT, BC, T0.30H, H2O2" /AntisenseName="yfkR" /AntisenseCor="-1.3937740774571999E-3" /AntisenseRegPval=0 /CDS_PredictionProba="NA" /TUshortSig="SigB" /TUshortPSig=1 /TUlongSig="SigA" /TUlongPSig="0.952" /label="S272" CDS complement(847282..847482) /gene="yfkS" /locus_tag="BSU_07770" /old_locus_tag="BSU07770" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 23625846; Product type rc: receptor" /codon_start=1 /transl_table=11 /product="putative spore germination D protein" /protein_id="NP_388658.1" /db_xref="EnsemblGenomes-Gn:BSU07770" /db_xref="EnsemblGenomes-Tr:CAB12606" /db_xref="GOA:O35036" /db_xref="SubtiList:BG12934" /db_xref="UniProtKB/Swiss-Prot:O35036" /translation="MISYIVQTLIVCIAIYAYEWKNFRSANNLTKWAFSLLIAGSAFL WIYMRVNPLLPRLGHLFKYIPF*" gene complement(847282..847482) /gene="yfkS" /locus_tag="BSU_07770" /old_locus_tag="BSU07770" CDS complement(847498..848652) /gene="yfkR" /locus_tag="BSU_07780" /old_locus_tag="BSU07780" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 10762253, 23625846; Product type f: factor" /codon_start=1 /transl_table=11 /product="putative spore germination protein" /protein_id="NP_388659.1" /db_xref="EnsemblGenomes-Gn:BSU07780" /db_xref="EnsemblGenomes-Tr:CAB12607" /db_xref="GOA:O35028" /db_xref="InterPro:IPR008844" /db_xref="SubtiList:BG12933" /db_xref="UniProtKB/Swiss-Prot:O35028" /translation="MKKTIYKCVLPLLICILLTGCWDRTEINDIAFVVSSAIDKKKDQ YRVAMQIPLVGQLGGQTGGGGGTAGSKTWYVDSASGTTIREANNKLQTSLSRTINTSH RRTVIIGEDMARDGVAPVFDILTRNPQNRLTALILVSRGEARDILNTDVQLEQFPAEM IRELAIIATSRPVFLSRFMSDLVEIGSDPYAPVISASKTKPGGKGKSNLKIDGLAIFK KDRLMDIFKDEHMTAALMLLNQARQPEFIVDLPNQMGQASIQLQKSNASFHAAEKNGK LSMTIEIRAKGIIMENQSTYETRENDQYYIIQKALNRTIKKDVISTVHRLQKLKADPA GFQDRTIRSTATTKNLLKKEWEEVYKDMEVHVVPIVTIEQGGVLYKTISH*" gene complement(847498..848652) /gene="yfkR" /locus_tag="BSU_07780" /old_locus_tag="BSU07780" CDS complement(848633..850174) /gene="yfkQ" /locus_tag="BSU_07790" /old_locus_tag="BSU07790" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 10762253, 23625846; Product type f: factor" /codon_start=1 /transl_table=11 /product="putative spore germination protein" /protein_id="NP_388660.1" /db_xref="EnsemblGenomes-Gn:BSU07790" /db_xref="EnsemblGenomes-Tr:CAB12608" /db_xref="GOA:O34486" /db_xref="InterPro:IPR004995" /db_xref="SubtiList:BG12932" /db_xref="UniProtKB/Swiss-Prot:O34486" /translation="MNKRDKALQLIKELEDNQDRPISPNLKENLENLTLLTEGCSDIV FRQFDFGNGLCGFIVYIEGIVKSEHIQDHALRPFLMHLTDQIDEHEEALQNTLSISSV ALETSMSKVAASIIEGNAVLFADGHSKGLILNIKGGQRRSIEEPITESTIRGSREGFT ESLRVNTALVRFRVKTFQLKMISFKIGTKTKTDVVLAYIDGLADPKVIDKAKKRIKKI KIDAVLESGYIEEFIEDDTYSPFPQLQYTERPDTVAAQLLEGRFAIFTDNTPFVLTGP ITFWQLMQASEDYYERYLMSNLIRWLRYMFLFVALYLPAIYVAVITYHQDLMPTNLMF SVASAREPIPFPAIIEALIMEISFEALREAGVRLPKTIGQTVSILGALVIGTAAVEAG IVSAPMVIIVSLTGIASFTIPRFNLAISIRMLRFPLMFLASIFGIFGIMLGTIILVLH LCKLQSFGIPYLSGISPFKRDEVKDIFVRAPWWTMTRRPGTYSRGNGQKGAKREDPKD EENNI*" gene complement(848633..850174) /gene="yfkQ" /locus_tag="BSU_07790" /old_locus_tag="BSU07790" promotor_-10 complement(850224..850235) /Source="Nicolas_upshift_promotors" /id="U594" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=879 /SigmaFactorBS="aacacttttttatagcgctttcatcctagtctGGAATATatg aaacagacaaGGTTACCCTAAAagtcacaagcacttattgaatatgacattaaaaagc a" /listShort="yfkQ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(850227) /Source="Nicolas_upshifts" /id="U594" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=879 /SigmaFactorBS="aacacttttttatagcgctttcatcctagtctGGAATATatg aaacagacaaGGTTACCCTAAAagtcacaagcacttattgaatatgacattaaaaagc a" /listShort="yfkQ" /GFF_Attribute="listLong" promotor_-35 complement(850249..850255) /Source="Nicolas_upshift_promotors" /id="U594" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=879 /SigmaFactorBS="aacacttttttatagcgctttcatcctagtctGGAATATatg aaacagacaaGGTTACCCTAAAagtcacaagcacttattgaatatgacattaaaaagc a" /listShort="yfkQ" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 850284..850291 /Source="Nicolas_upshift_promotors" /id="U595" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.99100899100899" /psig=1 /xcortree=1569 /SigmaFactorBS="tccagactaggatgaaagcgctataaaaaagTGTTGACTacc tgtatatacagGAATACAATATGATTATAAGttgtatatacaagttataaaaacggat a" /listShort="treP, treA, treR, yfkO" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 850306..850325 /Source="Nicolas_upshift_promotors" /id="U595" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.99100899100899" /psig=1 /xcortree=1569 /SigmaFactorBS="tccagactaggatgaaagcgctataaaaaagTGTTGACTacc tgtatatacagGAATACAATATGATTATAAGttgtatatacaagttataaaaacggat a" /listShort="treP, treA, treR, yfkO" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 850313 /Source="Nicolas_upshifts" /id="U595" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.99100899100899" /psig=1 /xcortree=1569 /SigmaFactorBS="tccagactaggatgaaagcgctataaaaaagTGTTGACTacc tgtatatacagGAATACAATATGATTATAAGttgtatatacaagttataaaaacggat a" /listShort="treP, treA, treR, yfkO" /GFF_Attribute="listLong" downshifts complement(850359) /Source="Nicolas_upshifts" /id="D386" /incds=0 /nref=1 /ntot=29 /MaxReadThrough="1.35091" /MaxDrop="3.57201" /score="22.8661179" /energy="-15.2" /TU="NA" /idTUdmin="U596" /TUdmin=0 /isTUend="TRUE" CDS 850367..851779 /gene="treP" /locus_tag="BSU_07800" /old_locus_tag="BSU07800" /EC_number="2.7.1.201" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:15849754, 16850406, 8755887, 8917076, 8969503, 18977770" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15849754, 16850406, 8755887, 8917076, 8969503, 18977770; Product type t : transporter" /codon_start=1 /transl_table=11 /product="phosphotransferase system (PTS) trehalose-specific enzyme IIBC component" /protein_id="NP_388661.1" /db_xref="EnsemblGenomes-Gn:BSU07800" /db_xref="EnsemblGenomes-Tr:CAB12609" /db_xref="GOA:P39794" /db_xref="InterPro:IPR001996" /db_xref="InterPro:IPR003352" /db_xref="InterPro:IPR004719" /db_xref="InterPro:IPR011296" /db_xref="InterPro:IPR013013" /db_xref="InterPro:IPR018113" /db_xref="InterPro:IPR036878" /db_xref="SubtiList:BG11009" /db_xref="UniProtKB/Swiss-Prot:P39794" /translation="MGELNKSARQIVEAVGGAENIAAATHCVTRLRFALIDESKVDQE MLDQIDVVKGSFSTNGQFQVVIGQGTVNKVYAELVKETGIGESTKDEVKKASEKNMNP LQRAVKTLADIFIPILPAIVTAGLLMGINNILTAEGIFFSTKSIVQVYPQWADLANMI NLIAGTAFTFLPALIGWSAVKRFGGNPLLGIVLGVMLVHPDLLNAWGYGAAEQSGEIP VWNLFGLEVQKVGYQGQVLPILLASYMLAKIEVFLTKRTPEGIQLLVVAPITLLLTGF ASFIIIGPITFAIGNVLTSGLISVFGSFAALGGLLYGGFYSALVITGMHHTFLAVDLQ LIGSKLGGTFLWPMLALSNIAQGSAALAMMFIVKDEKQKGLSLTSGISAYLGITEPAI FGVNLRYRFPFIIAMVSSGLAGMYISSQGVLASSVGVGGVPGIFSIMSQYWGAFAIGM AIVLIVPFAGTYAYARFKHK*" gene 850367..851779 /gene="treP" /locus_tag="BSU_07800" /old_locus_tag="BSU07800" promotor_no_box complement(850385..850485) /Source="Nicolas_upshift_promotors" /id="U596" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.66033966033966" /psig="0.0889110889110889" /xcortree=1570 /SigmaFactorBS="ttgctttcatctattaaagcaaaacgcaaacgtgtaacacaa tgagttgccgctgcaatattttcagcaccgccgactgcttcgacaatctgacgtgccg a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_no_box" upshifts complement(850425) /Source="Nicolas_upshifts" /id="U596" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.66033966033966" /psig="0.0889110889110889" /xcortree=1570 /SigmaFactorBS="ttgctttcatctattaaagcaaaacgcaaacgtgtaacacaa tgagttgccgctgcaatattttcagcaccgccgactgcttcgacaatctgacgtgccg a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" CDS 851850..853535 /gene="treA" /locus_tag="BSU_07810" /old_locus_tag="BSU07810" /EC_number="3.2.1.93" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:7651129, 7751281, 8755887, 8917076, 9701821, 26894535" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7651129, 7751281, 8755887, 8917076, 9701821, 26894535; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="trehalose-6-phosphate hydrolase" /protein_id="NP_388662.1" /db_xref="EnsemblGenomes-Gn:BSU07810" /db_xref="EnsemblGenomes-Tr:CAB12610" /db_xref="GOA:P39795" /db_xref="InterPro:IPR006047" /db_xref="InterPro:IPR012769" /db_xref="InterPro:IPR017853" /db_xref="InterPro:IPR032091" /db_xref="SubtiList:BG11010" /db_xref="UniProtKB/Swiss-Prot:P39795" /translation="MKTEQTPWWKKAVVYQIYPKSFNDTTGNGVGDLNGIIEKLDYLK TLQVDVLWLTPIYDSPQHDNGYDIRDYYSIYPEYGTMEDFERLVSEAHKRDLKVVMDL VVNHTSTEHKWFREAISSIDSPYRDFYIWKKPQENGSVPTNWESKFGGSAWELDEASG QYYLHLFDVTQADLNWENEEVRKHVYDMMHFWFEKGIDGFRLDVINLISKDQRFPNAE EGDGRSFYTDGPRVHEFLHEMNEKVFSHYDSMTVGEMSSTTVDHCIRYTNPDNKELDM TFSFHHLKVDYPNGEKWALAPFDFLKLKEILSDWQTGMHAGGGWNALFWCNHDQPRVV SRYGDDGAYRVKSAKMLATAIHMMQGTPYIYQGEELGMTNPKFTDISSYRDVESLNMY HAFKEKGMADQDITAILQAKSRDNSRTPVQWDATENGGFTTGTPWIPVAGNYREINAE AALRDQNSVFYHYQKLIQIRKMYDIVTEGTYEIIAKDDPNIFAYLRHGSNEKLLVINN FYGTEAAFTLPDSLAPDEWKAEVLLTNDEAREGLQNMTLRPYESIVYRLTKPC*" gene 851850..853535 /gene="treA" /locus_tag="BSU_07810" /old_locus_tag="BSU07810" promotor_-10 complement(852156..852171) /Source="Nicolas_upshift_promotors" /id="U597" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1694 /SigmaFactorBS="tacgggctgtctattgaagagatcgcctcgCGAAACCATTtg tgctctgttgACGTATGATTGACAACaagatccatgacgactttcaggtctcttttat g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(852163) /Source="Nicolas_upshifts" /id="U597" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1694 /SigmaFactorBS="tacgggctgtctattgaagagatcgcctcgCGAAACCATTtg tgctctgttgACGTATGATTGACAACaagatccatgacgactttcaggtctcttttat g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(852184..852193) /Source="Nicolas_upshift_promotors" /id="U597" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1694 /SigmaFactorBS="tacgggctgtctattgaagagatcgcctcgCGAAACCATTtg tgctctgttgACGTATGATTGACAACaagatccatgacgactttcaggtctcttttat g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 853508..853512 /Source="Nicolas_upshift_promotors" /id="U598" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.967032967032967" /psig=1 /xcortree=2516 /SigmaFactorBS="ggcttcagaacatgacgcttcgcccatatgagtccatTGTTT atcgtttaacgaaacCGTGTTAAACTAAGCTGGGTggtccataatgaaggtgaataaa t" /listShort="treR, yfkO" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 853528..853547 /Source="Nicolas_upshift_promotors" /id="U598" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.967032967032967" /psig=1 /xcortree=2516 /SigmaFactorBS="ggcttcagaacatgacgcttcgcccatatgagtccatTGTTT atcgtttaacgaaacCGTGTTAAACTAAGCTGGGTggtccataatgaaggtgaataaa t" /listShort="treR, yfkO" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 853531 /Source="Nicolas_upshifts" /id="U598" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.967032967032967" /psig=1 /xcortree=2516 /SigmaFactorBS="ggcttcagaacatgacgcttcgcccatatgagtccatTGTTT atcgtttaacgaaacCGTGTTAAACTAAGCTGGGTggtccataatgaaggtgaataaa t" /listShort="treR, yfkO" /GFF_Attribute="listLong" CDS 853556..854272 /gene="treR" /locus_tag="BSU_07820" /old_locus_tag="BSU07820" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:8755887, 9829827, 17705272" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8755887, 9829827, 17705272; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator (TreR-trehalose)" /protein_id="NP_388663.1" /db_xref="EnsemblGenomes-Gn:BSU07820" /db_xref="EnsemblGenomes-Tr:CAB12611" /db_xref="GOA:P39796" /db_xref="InterPro:IPR000524" /db_xref="InterPro:IPR011663" /db_xref="InterPro:IPR012770" /db_xref="InterPro:IPR028978" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="PDB:2OGG" /db_xref="SubtiList:BG11011" /db_xref="UniProtKB/Swiss-Prot:P39796" /translation="MKVNKFITIYKDIAQQIEGGRWKAEEILPSEHELTAQYGTSRET VRKALHMLAQNGYIQKIRGKGSVVLNREKMQFPVSGLVSFKELAQTLGKETKTTVHKF GLEPPSELIQKQLRANLDDDIWEVIRSRKIDGEHVILDKDYFFRKHVPHLTKEICENS IYEYIEGELGLSISYAQKEIVAEPCTDEDRELLDLRGYDHMVVVRNYVFLEDTSLFQY TESRHRLDKFRFVDFARRGK*" gene 853556..854272 /gene="treR" /locus_tag="BSU_07820" /old_locus_tag="BSU07820" downshifts 854265 /Source="Nicolas_upshifts" /id="D387" /incds=0 /nref=3 /ntot=115 /MaxReadThrough="6.58905" /MaxDrop="4.05981" /score="24.6748216" /energy="-11.1" /TU="U595,U598" /idTUdmin="U595" /TUdmin="-792" /isTUend="FALSE" promotor_-35 854347..854350 /Source="Nicolas_upshift_promotors" /id="U599" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.432567432567433" /psig="0.995004995004995" /xcortree=611 /SigmaFactorBS="caaaattgatactatccaacaaaaatgtgcgtACTTttactt tttatcataATGGCTACAATAGAGATGAGagtaatctaaaggagaggtgttttacatg g" /listShort="yfkO" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 854366..854385 /Source="Nicolas_upshift_promotors" /id="U599" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.432567432567433" /psig="0.995004995004995" /xcortree=611 /SigmaFactorBS="caaaattgatactatccaacaaaaatgtgcgtACTTttactt tttatcataATGGCTACAATAGAGATGAGagtaatctaaaggagaggtgttttacatg g" /listShort="yfkO" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 854375 /Source="Nicolas_upshifts" /id="U599" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.432567432567433" /psig="0.995004995004995" /xcortree=611 /SigmaFactorBS="caaaattgatactatccaacaaaaatgtgcgtACTTttactt tttatcataATGGCTACAATAGAGATGAGagtaatctaaaggagaggtgttttacatg g" /listShort="yfkO" /GFF_Attribute="listLong" CDS 854412..855077 /gene="hypO" /locus_tag="BSU_07830" /old_locus_tag="BSU07830" /EC_number="1.5.1.39" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:15252706, 20727918, 20862523, 22238377, 26415543" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15252706, 20727918, 20862523, 22238377, 26415543; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="NAD(P)H-flavin oxidoreductase (nitroreductase)" /protein_id="NP_388664.1" /db_xref="EnsemblGenomes-Gn:BSU07830" /db_xref="EnsemblGenomes-Tr:CAB12612" /db_xref="GOA:O34475" /db_xref="InterPro:IPR000415" /db_xref="InterPro:IPR029479" /db_xref="InterPro:IPR033878" /db_xref="SubtiList:BG12931" /db_xref="UniProtKB/Swiss-Prot:O34475" /translation="MADLKTQILDAYNFRHATKEFDPNKKVSDSDFEFILETGRLSPS SLGLEPWKFVVVQNPEFREKLREYTWGAQKQLPTASHFVLILARTAKDIKYNADYIKR HLKEVKQMPQDVYEGYLSKTEEFQKNDLHLLESDRTLFDWASKQTYIALGNMMTAAAQ IGVDSCPIEGFQYDHIHRILEEEGLLENGSFDISVMVAFGYRVRDPRPKTRSAVEDVV KWV*" gene 854412..855077 /gene="hypO" /locus_tag="BSU_07830" /old_locus_tag="BSU07830" downshifts 855058 /Source="Nicolas_upshifts" /id="D388" /incds=0 /nref=180 /ntot=269 /MaxReadThrough="0.70079" /MaxDrop="6.77615" /score="34.5750428" /energy="-16.9" /TU="NA" /idTUdmin="U595" /TUdmin=1 /isTUend="TRUE" CDS complement(855114..859502) /gene="yfkN" /locus_tag="BSU_07840" /old_locus_tag="BSU07840" /EC_number="3.1.4.16" /EC_number="3.1.3.5" /EC_number="3.1.3.6" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 14688230, 16291680, 21800427, 21906378, 25355936; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="exported 2',3'-cyclic-nucleotide 2'-phosphodiesterase, 2' (or 3') nucleotidase and 5' nucleotidase" /protein_id="NP_388665.1" /db_xref="EnsemblGenomes-Gn:BSU07840" /db_xref="EnsemblGenomes-Tr:CAB12613" /db_xref="GOA:O34313" /db_xref="InterPro:IPR004843" /db_xref="InterPro:IPR006146" /db_xref="InterPro:IPR006179" /db_xref="InterPro:IPR008334" /db_xref="InterPro:IPR029052" /db_xref="InterPro:IPR036907" /db_xref="PDB:3GVE" /db_xref="SubtiList:BG12930" /db_xref="UniProtKB/Swiss-Prot:O34313" /translation="MRIQKRRTHVENILRILLPPIMILSLILPTPPIHAEESAAPQVH LSILATTDIHANMMDYDYYSDKETADFGLARTAQLIQKHREQNPNTLLVDNGDLIQGN PLGEYAVKYQKDDIISGTKTHPIISVMNALKYDAGTLGNHEFNYGLDFLDGTIKGADF PIVNANVKTTSGENRYTPYVINEKTLIDENGNEQKVKVGYIGFVPPQIMTWDKKNLEG QVQVQDIVESANETIPKMKAEGADVIIALAHTGIEKQAQSSGAENAVFDLATKTKGID AIISGHQHGLFPSAEYAGVAQFNVEKGTINGIPVVMPSSWGKYLGVIDLKLEKADGSW KVADSKGSIESIAGNVTSRNETVTNTIQQTHQNTLEYVRKPVGKTEADINSFFAQVKD DPSIQIVTDAQKWYAEKEMKDTEYKNLPILSAGAPFKAGGRNGANYYTNIPAGDLAIK NVGDLYLYDNTVQIVKLTGSEVKDWLEMSAGQFNQIDPAKGGDQALLNENFRSYNFDV IDGVTYQVDVTKPAKYNENGKVINADSSRIINLSYEGKPISPSQEFLVVTNNYRASGG GGFPHLTSDKIVHGSAVENRQVLMDYIIEQKTVNPKADNNWSIAPVSGTNLTFESSLL AKPFADKADDVAYVGKSANEGYGVYKLQFDDDSNPDPPKDGLWDLTVMHTNDTHAHLD DAARRMTKINEVRSETNHNILLDAGDVFSGDLYFTKWNGLADLKMMNMMGYDAMTFGN HEFDKGPTVLSDFLSGNSATVDPANRYHFEAPEFPIVSANVDVSNEPKLKSFVKKPQT FTAGEKKEAGIHPYILLDVDGEKVAVFGLTTEDTATTSSPGKSIVFNDAFETAQNTVK AIQEEEKVNKIIALTHIGHNRDLELAKKVKGIDLIIGGHTHTLVDKMEVVNNEEPTIV AQAKEYGQFLGRVDVAFDEKGVVQTDKSNLSVLPIDEHTEENPEAKQELDQFKNELED VKNEKVGYTDVALDGQREHVRTKETNLGNFIADGMLAKAKEAAGARIAITNGGGIRAG IDKGDITLGEVLNVMPFGNTLYVADLTGKQIKEALEQGLSNVENGGGAFPQVAGIEYT FTLNNKPGHRVLEVKIESPNGDKVAINTDDTYRVATNNFVGAGGDGYSVFTEASHGED LGYVDYEIFTEQLKKLGNKVSPKVEGRIKEVFLPTKQKDGSWTLDEDKFAIYAKNANT PFVYYGIHEGSQEKPINLKVKKDQVKLLKERESDPSLTMFNYWYSMKMPMANLKTADT AIGIKSTGELDVSLSDVYDFTVKQKGKEIKSFKEPVQLSLRMFDIEEAHNPAIYHVDR KKKAFTKTGHGSVDDDMVTGYTNHFSEYTILNSGSNNKPPAFPSDQPTGGDDGNHGGG SDKPGGKQPTDGNGGNDTPPGTQPTNGSGGNGSGGSGTDGPAGGLLPDTATSMYSILL AGFLISALGTAMYLHQRRKQNRANQA*" gene complement(855114..859502) /gene="yfkN" /locus_tag="BSU_07840" /old_locus_tag="BSU07840" downshifts complement(855133) /Source="Nicolas_upshifts" /id="D389" /incds=0 /nref=155 /ntot=229 /MaxReadThrough="1.00159" /MaxDrop="7.08591" /score="22.8661179" /energy="-15.2" /TU="NA" /idTUdmin="U600" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(859535..859554) /Source="Nicolas_upshift_promotors" /id="U600" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.944055944055944" /psig="0.994005994005994" /xcortree=462 /SigmaFactorBS="actcatttttctcccttttacaataatcataaagaaacacCT ACaaatagttacaaaaTATTCTTACAATAGGAGCTGtaacacaaatttcgttgaaagg t" /listShort="yfkN" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(859552) /Source="Nicolas_upshifts" /id="U600" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.944055944055944" /psig="0.994005994005994" /xcortree=462 /SigmaFactorBS="actcatttttctcccttttacaataatcataaagaaacacCT ACaaatagttacaaaaTATTCTTACAATAGGAGCTGtaacacaaatttcgttgaaagg t" /listShort="yfkN" /GFF_Attribute="listLong" promotor_-35 complement(859569..859572) /Source="Nicolas_upshift_promotors" /id="U600" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.944055944055944" /psig="0.994005994005994" /xcortree=462 /SigmaFactorBS="actcatttttctcccttttacaataatcataaagaaacacCT ACaaatagttacaaaaTATTCTTACAATAGGAGCTGtaacacaaatttcgttgaaagg t" /listShort="yfkN" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 859679..859685 /Source="Nicolas_upshift_promotors" /id="U601" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=231 /SigmaFactorBS="tgggcatttatgcttatcgtttgtcacaatcgcggaaTGTTT ATtttagtgtggctgGGGTAGAGTGTTTTATGTAgacatataaagcgggaggttatga a" /listShort="yfkM, S273, yfkJ, yfkI, yfkH, S275" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 859699..859717 /Source="Nicolas_upshift_promotors" /id="U601" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=231 /SigmaFactorBS="tgggcatttatgcttatcgtttgtcacaatcgcggaaTGTTT ATtttagtgtggctgGGGTAGAGTGTTTTATGTAgacatataaagcgggaggttatga a" /listShort="yfkM, S273, yfkJ, yfkI, yfkH, S275" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 859702 /Source="Nicolas_upshifts" /id="U601" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=231 /SigmaFactorBS="tgggcatttatgcttatcgtttgtcacaatcgcggaaTGTTT ATtttagtgtggctgGGGTAGAGTGTTTTATGTAgacatataaagcgggaggttatga a" /listShort="yfkM, S273, yfkJ, yfkI, yfkH, S275" /GFF_Attribute="listLong" CDS 859745..860263 /gene="sufLB" /locus_tag="BSU_07850" /old_locus_tag="BSU07850" /function="16.6: Maintain" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:10220166, 12354229, 16181642, 17257049, 17933887, 24330391, 25283443, 25561404" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10220166, 12354229, 16181642, 17257049, 17933887, 24330391, 25283443, 25561404; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="general stress protein 18; deglycase" /protein_id="NP_388666.1" /db_xref="EnsemblGenomes-Gn:BSU07850" /db_xref="EnsemblGenomes-Tr:CAB12614" /db_xref="GOA:P80876" /db_xref="InterPro:IPR002818" /db_xref="InterPro:IPR006286" /db_xref="InterPro:IPR029062" /db_xref="SubtiList:BG12929" /db_xref="UniProtKB/Swiss-Prot:P80876" /translation="MGKKIAVVLTYYFEDSEYTEPAKAFKEAGHELTVIEKEKGKTVK GKQGTAEVTVDASIDDVNSSDFDALLIPGGFSPDQLRADDRFVQFTKAFMTDKKPVFA ICHGPQLLINAKALDGRKATGYTSIRVDMENAGADVVDKEVVVCQDQLVTSRTPDDIP AFNRESLALLEK*" gene 859745..860263 /gene="sufLB" /locus_tag="BSU_07850" /old_locus_tag="BSU07850" downshifts 860249 /Source="Nicolas_upshifts" /id="D390" /incds=0 /nref=35 /ntot=153 /MaxReadThrough="8.02255" /MaxDrop="6.97573" /score="42.2080398" /energy="-12.9" /TU="U601" /idTUdmin="U601" /TUdmin="-3542" /isTUend="FALSE" downshifts complement(860293) /Source="Nicolas_upshifts" /id="D391" /incds=0 /nref=22 /ntot=199 /MaxReadThrough="1.59285" /MaxDrop="3.61098" /score="31.1923457" /energy="-11.1" /TU="NA" /idTUdmin="U602" /TUdmin=10 /isTUend="TRUE" S_feature 860294..861944 /Source="Nicolas_S_feature" /locus_tag="new_860294_861944" /HighExp="Etha, S6, S8, S5, S7, Gly, Salt, LoTm, S4, Diami" /AntisenseName="yfkL" /AntisenseCor="-0.52109661167911703" /AntisenseRegPval="-19.399999999999999" /CDS_PredictionProba="NA" /TUshortSig="SigB" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S273" CDS complement(860303..861493) /gene="yfkL" /locus_tag="BSU_07860" /old_locus_tag="BSU07860" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 15849754, 16828913, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="efflux transporter" /protein_id="NP_388667.1" /db_xref="EnsemblGenomes-Gn:BSU07860" /db_xref="EnsemblGenomes-Tr:CAB12615" /db_xref="GOA:O34597" /db_xref="InterPro:IPR005829" /db_xref="InterPro:IPR011701" /db_xref="InterPro:IPR020846" /db_xref="InterPro:IPR036259" /db_xref="SubtiList:BG12928" /db_xref="UniProtKB/Swiss-Prot:O34597" /translation="MQTTSIKTASGMYINYFFLGMVNIILASNMSSLTKQWNTDPTGI SYVIAAIGFGKLLTYGISGVLSDKIGRKPLVVASAGIMAVFLVGIPLSPSYELAFVFA LLAGVANSAMDAGTYPALTELFPSASGSANVLVKAFMSVGAALLPLLITFLADHSMFY GFAFYLPAAVYLLNIIYLSTLSFPKKHKKPTNSGQQESPVFLSEPVFQKEGTALIIIG FTSTALFTVSQIWLPSYAQKAAGLAESASVQLLSYYSIGSLASVLLLAVLLNRWVKPV FITLLYPIITLCTLAVMLTVHIPVVLDITAFFLGFSTAGVFQITITLMTELFWKRKGT VTGIVATASSLASILLPIATGLIAKAGGIAHIFIFDFGIAVIGTAAAAFLYYRYKKLT GAQA*" gene complement(860303..861493) /gene="yfkL" /locus_tag="BSU_07860" /old_locus_tag="BSU07860" S_feature complement(861494..861585) /Source="Nicolas_S_feature" /locus_tag="new_861494_861585_c" /HighExp="C90, MG 10, BMM, MG-0.2, MG t5, MG 5, MG-0.1, UNK1, HPh, LPh" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.994" /TUlongSig="NA" /TUlongPSig="NA" /label="S274" CDS complement(861586..861801) /gene="yfkK" /locus_tag="BSU_07870" /old_locus_tag="BSU07870" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_388668.1" /db_xref="EnsemblGenomes-Gn:BSU07870" /db_xref="EnsemblGenomes-Tr:CAB12616" /db_xref="InterPro:IPR009507" /db_xref="SubtiList:BG12927" /db_xref="UniProtKB/Swiss-Prot:O35019" /translation="MSSPNTETLTQMIEEISQKLNMLNVGVIKAEDFSDEKIEDLTYL HRMVMKKESFSPSEMQAIAQELASLRK*" gene complement(861586..861801) /gene="yfkK" /locus_tag="BSU_07870" /old_locus_tag="BSU07870" downshifts complement(861645) /Source="Nicolas_upshifts" /id="D392" /incds=0 /nref=1 /ntot=131 /MaxReadThrough="3.65318" /MaxDrop="2.45155" /score="16.183887" /energy="-11.6" /TU="U602" /idTUdmin="U602" /TUdmin="-1342" /isTUend="FALSE" promotor_-10 complement(861833..861852) /Source="Nicolas_upshift_promotors" /id="U602" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.593406593406593" /psig="0.994005994005994" /xcortree=3074 /SigmaFactorBS="tcacttttttggaatgaacagcctgcttttagaatagggTTt ttttctgatggaaTTCTGTTAGAATAAAACATAcctatattgcgcatagaaaggatgg a" /listShort="yfkK, S274, yfkL" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(861847) /Source="Nicolas_upshifts" /id="U602" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.593406593406593" /psig="0.994005994005994" /xcortree=3074 /SigmaFactorBS="tcacttttttggaatgaacagcctgcttttagaatagggTTt ttttctgatggaaTTCTGTTAGAATAAAACATAcctatattgcgcatagaaaggatgg a" /listShort="yfkK, S274, yfkL" /GFF_Attribute="listLong" promotor_-35 complement(861867..861868) /Source="Nicolas_upshift_promotors" /id="U602" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.593406593406593" /psig="0.994005994005994" /xcortree=3074 /SigmaFactorBS="tcacttttttggaatgaacagcctgcttttagaatagggTTt ttttctgatggaaTTCTGTTAGAATAAAACATAcctatattgcgcatagaaaggatgg a" /listShort="yfkK, S274, yfkL" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 861914..861921 /Source="Nicolas_upshift_promotors" /id="U603" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.82017982017982" /psig="0.994005994005994" /xcortree=134 /SigmaFactorBS="gctgttcattccaaaaaagtgaagacatCAGTTGAAaagaaa atgaacatCCTACTAAGATATTCATGAAggtttctttttagagaaataggggcaaaga a" /listShort="yfkJ, yfkI, yfkH, S275" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 861936..861955 /Source="Nicolas_upshift_promotors" /id="U603" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.82017982017982" /psig="0.994005994005994" /xcortree=134 /SigmaFactorBS="gctgttcattccaaaaaagtgaagacatCAGTTGAAaagaaa atgaacatCCTACTAAGATATTCATGAAggtttctttttagagaaataggggcaaaga a" /listShort="yfkJ, yfkI, yfkH, S275" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 861946 /Source="Nicolas_upshifts" /id="U603" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.82017982017982" /psig="0.994005994005994" /xcortree=134 /SigmaFactorBS="gctgttcattccaaaaaagtgaagacatCAGTTGAAaagaaa atgaacatCCTACTAAGATATTCATGAAggtttctttttagagaaataggggcaaaga a" /listShort="yfkJ, yfkI, yfkH, S275" /GFF_Attribute="listLong" CDS 862004..862474 /gene="yfkJ" /locus_tag="BSU_07880" /old_locus_tag="BSU07880" /EC_number="3.1.3.48" /function="16.8: Protect" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:15995210" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15995210; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="protein-tyrosine-phosphatase" /protein_id="NP_388669.1" /db_xref="EnsemblGenomes-Gn:BSU07880" /db_xref="EnsemblGenomes-Tr:CAB12617" /db_xref="GOA:O35016" /db_xref="InterPro:IPR017867" /db_xref="InterPro:IPR023485" /db_xref="InterPro:IPR036196" /db_xref="PDB:4ETM" /db_xref="SubtiList:BG12926" /db_xref="UniProtKB/Swiss-Prot:O35016" /translation="MISVLFVCLGNICRSPMAEAIFRDLAAKKGLEGKIKADSAGIGG WHIGNPPHEGTQEILRREGISFDGMLARQVSEQDLDDFDYIIAMDAENIGSLRSMAGF KNTSHIKRLLDYVEDSDLADVPDPYYTGNFEEVCQLIKTGCEQLLASIQKEKQL*" gene 862004..862474 /gene="yfkJ" /locus_tag="BSU_07880" /old_locus_tag="BSU07880" CDS 862492..862812 /gene="yfkI" /locus_tag="BSU_07890" /old_locus_tag="BSU07890" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 15995210" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_388670.1" /db_xref="EnsemblGenomes-Gn:BSU07890" /db_xref="EnsemblGenomes-Tr:CAB12618" /db_xref="SubtiList:BG12925" /db_xref="UniProtKB/Swiss-Prot:O34418" /translation="MNNERLMLKGIFLGAAAGAALSLLHKPTRQACGMRWLTCKHKLS LYKSNPELLKNTVITKVDEAKKLARTLSKEVDFVNQQVKELKKTTPQVMELVQETKEH FSKK*" gene 862492..862812 /gene="yfkI" /locus_tag="BSU_07890" /old_locus_tag="BSU07890" CDS 862836..863663 /gene="rbn" /locus_tag="BSU_07900" /old_locus_tag="BSU07900" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 11222749, 12794188, 15849754, 16850406, 15764599; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative ribonuclease BN" /protein_id="NP_388671.1" /db_xref="EnsemblGenomes-Gn:BSU07900" /db_xref="EnsemblGenomes-Tr:CAB12619" /db_xref="GOA:O34437" /db_xref="InterPro:IPR017039" /db_xref="SubtiList:BG12924" /db_xref="UniProtKB/Swiss-Prot:O34437" /translation="MSFLKELFSRYTLHEGQSKSAELAYFFLLSLFPFLIFMLTLTAY LPLSTDDVLGVIEQYAPASAMSLVESITHQTLNNRNGGLLSFGIIAALWSASNGMNAI VRSLNHAYDVEENRSFIIVRLTSIFLTIAMVFTILVALLLPVFGREIGRLASDFVGAS DLFLSVWAAIRWGVSPLVLLIVFSALYVIAPNKKLSLRFVMPGAVFATIGWIIVSTLF SFYVSTFANYSATYGSIGGIIVLMIWFYLSGILIILGGEINALLHKRKKLPDENPYH* " gene 862836..863663 /gene="rbn" /locus_tag="BSU_07900" /old_locus_tag="BSU07900" promotor_-35 863642..863648 /Source="Nicolas_upshift_promotors" /id="U604" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.974025974025974" /psig="0.974025974025974" /xcortree=847 /SigmaFactorBS="acataaacgtaaaaagcttccTGATGAAaatccctaccatta GCGCACCCTATAaacgaacttcggttcaaaaagaagtcggggggatatcgtgatgacc a" /listShort="S275" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 863663..863674 /Source="Nicolas_upshift_promotors" /id="U604" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.974025974025974" /psig="0.974025974025974" /xcortree=847 /SigmaFactorBS="acataaacgtaaaaagcttccTGATGAAaatccctaccatta GCGCACCCTATAaacgaacttcggttcaaaaagaagtcggggggatatcgtgatgacc a" /listShort="S275" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 863681..863837 /Source="Nicolas_S_feature" /locus_tag="new_863681_863837" /HighExp="S8, Etha, S6, Salt, S7, S5, ferm, nit, BT, Sw" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.99976299999999996" /TUshortSig="SigGF, SigA, SigB" /TUshortPSig="0.974, 0.994, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S275" upshifts 863681 /Source="Nicolas_upshifts" /id="U604" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.974025974025974" /psig="0.974025974025974" /xcortree=847 /SigmaFactorBS="acataaacgtaaaaagcttccTGATGAAaatccctaccatta GCGCACCCTATAaacgaacttcggttcaaaaagaagtcggggggatatcgtgatgacc a" /listShort="S275" /GFF_Attribute="listLong" downshifts complement(863713) /Source="Nicolas_upshifts" /id="D393" /incds=0 /nref=1 /ntot=4 /MaxReadThrough="1.22239" /MaxDrop="3.61507" /score="-5.45682213" /energy="-3" /TU="NA" /idTUdmin="U606" /TUdmin=440 /isTUend="FALSE" downshifts 863812 /Source="Nicolas_upshifts" /id="D394" /incds=0 /nref=144 /ntot=253 /MaxReadThrough="1.4253" /MaxDrop="6.85849" /score="25.8200126" /energy="-17.9" /TU="NA" /idTUdmin="U603" /TUdmin="-1" /isTUend="TRUE" CDS complement(863862..865037) /gene="yfkF" /locus_tag="BSU_07910" /old_locus_tag="BSU07910" /function="16.1: Circulate" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative efflux transporter" /protein_id="NP_388672.1" /db_xref="EnsemblGenomes-Gn:BSU07910" /db_xref="EnsemblGenomes-Tr:CAB12620" /db_xref="GOA:O34929" /db_xref="InterPro:IPR011701" /db_xref="InterPro:IPR020846" /db_xref="InterPro:IPR036259" /db_xref="SubtiList:BG12923" /db_xref="UniProtKB/Swiss-Prot:O34929" /translation="MSRFHFFILVLLVSISGFSQGMLLPVISIIFETNGESAAINGLH ATGLYIGVLLASPFMEAPLRKLGFKPLIVMGGSIVILSLFGFIWLQSVWVWFLLRLFI GIGDHMLHFSTQTWVTSMSSKQNRGRNLSIYGLSFGLGFAAGPFMVPLVKLSPSLPFI VSGCISLFAWLFVFFLQNAYPETSPHETKSDNSFRRFYQAMLFGWVAFMPTFGYGFLE TALNGSFPVYALRLGISVDAVAIILPAFAIGSIIFQFPLGILSDKYGRRNVLLVILLT GALCFFIAGVFPSPYVIGGCFFIAGMAVGSTFTLGISYMTDLLPPHLLPAGNLLCGIT FSLGSILGPVAGGWYMQTFESANLFYFITLTLSSVWLALVLGKPKSWSPAETYSSSS* " gene complement(863862..865037) /gene="yfkF" /locus_tag="BSU_07910" /old_locus_tag="BSU07910" downshifts complement(863867) /Source="Nicolas_upshifts" /id="D395" /incds=0 /nref=1 /ntot=97 /MaxReadThrough="0.37084" /MaxDrop="3.28031" /score="3.2266059" /energy="-14.1" /TU="NA" /idTUdmin="U606" /TUdmin=286 /isTUend="FALSE" promotor_-35 864474..864480 /Source="Nicolas_upshift_promotors" /id="U605" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=204 /SigmaFactorBS="cctgataaaatcgcctgaaactattgtctgatttGGTTTCAt gaggactggtttccGGGTATGCATTTTGTAGAAagaaaacaaaaagccacgcaaacag a" /listShort="S276, yfkE, yfkD" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 864496..864514 /Source="Nicolas_upshift_promotors" /id="U605" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=204 /SigmaFactorBS="cctgataaaatcgcctgaaactattgtctgatttGGTTTCAt gaggactggtttccGGGTATGCATTTTGTAGAAagaaaacaaaaagccacgcaaacag a" /listShort="S276, yfkE, yfkD" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 864500..865153 /Source="Nicolas_S_feature" /locus_tag="new_864500_865153" /HighExp="Etha, M9-stat, Salt, Sw, Gly, B60, Heat, LPhT, HiTm, T0.30H" /AntisenseName="yfkF" /AntisenseCor="-0.18505347560608301" /AntisenseRegPval="-2.6" /CDS_PredictionProba="NA" /TUshortSig="SigB" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S276" upshifts 864500 /Source="Nicolas_upshifts" /id="U605" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=204 /SigmaFactorBS="cctgataaaatcgcctgaaactattgtctgatttGGTTTCAt gaggactggtttccGGGTATGCATTTTGTAGAAagaaaacaaaaagccacgcaaacag a" /listShort="S276, yfkE, yfkD" /GFF_Attribute="listLong" promotor_-10 complement(865062..865081) /Source="Nicolas_upshift_promotors" /id="U606" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.74925074925075" /psig=1 /xcortree=3138 /SigmaFactorBS="gagggcaaatgtatagcgtgatataggcttttttcAGGTTGC CtgcttttggaaaaCGTTGTACGATCAACATAGAttccatataaggagaactgacacg a" /listShort="yfkF" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(865077) /Source="Nicolas_upshifts" /id="U606" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.74925074925075" /psig=1 /xcortree=3138 /SigmaFactorBS="gagggcaaatgtatagcgtgatataggcttttttcAGGTTGC CtgcttttggaaaaCGTTGTACGATCAACATAGAttccatataaggagaactgacacg a" /listShort="yfkF" /GFF_Attribute="listLong" promotor_-35 complement(865095..865102) /Source="Nicolas_upshift_promotors" /id="U606" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.74925074925075" /psig=1 /xcortree=3138 /SigmaFactorBS="gagggcaaatgtatagcgtgatataggcttttttcAGGTTGC CtgcttttggaaaaCGTTGTACGATCAACATAGAttccatataaggagaactgacacg a" /listShort="yfkF" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 865143..865148 /Source="Nicolas_upshift_promotors" /id="U607" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.848151848151848" /psig="0.848151848151848" /xcortree=1179 /SigmaFactorBS="ggcaacctgaaaaaagcctatatcacgctatacatttgccct cgtgtaATCATGaaggtttttgtgaaGAATAAAAATAAAACAAGTcataaaaaaggag c" /listShort="yfkE" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 865155 /Source="Nicolas_upshifts" /id="U607" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.848151848151848" /psig="0.848151848151848" /xcortree=1179 /SigmaFactorBS="ggcaacctgaaaaaagcctatatcacgctatacatttgccct cgtgtaATCATGaaggtttttgtgaaGAATAAAAATAAAACAAGTcataaaaaaggag c" /listShort="yfkE" /GFF_Attribute="listLong" promotor_-10 865163..865181 /Source="Nicolas_upshift_promotors" /id="U607" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.848151848151848" /psig="0.848151848151848" /xcortree=1179 /SigmaFactorBS="ggcaacctgaaaaaagcctatatcacgctatacatttgccct cgtgtaATCATGaaggtttttgtgaaGAATAAAAATAAAACAAGTcataaaaaaggag c" /listShort="yfkE" /GFF_Attribute="listLong" /label="promotor_-10" CDS 865205..866260 /gene="chaA" /locus_tag="BSU_07920" /old_locus_tag="BSU07920" /function="16.8: Protect" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:15849754, 16850406, 19543710, 23798403" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15849754, 16850406, 19543710, 23798403; Product type t: transporter" /codon_start=1 /transl_table=11 /product="H+/Ca2+ antiporter" /protein_id="NP_388673.1" /db_xref="EnsemblGenomes-Gn:BSU07920" /db_xref="EnsemblGenomes-Tr:CAB12621" /db_xref="GOA:O34840" /db_xref="InterPro:IPR004713" /db_xref="InterPro:IPR004798" /db_xref="InterPro:IPR004837" /db_xref="PDB:4KJR" /db_xref="PDB:4KJS" /db_xref="SubtiList:BG12922" /db_xref="UniProtKB/Swiss-Prot:O34840" /translation="MNRIFFILVAAGVPLSVIGSLMHWPSAVLFAVYCVTIIALASYM GRATESLSIIAGPRIGGLLNATFGNAVELIISLFALKEGLTGIVLASLTGSVLGNLLL VAGLSFFVGGLKYKRQEFNIHDARHNSGLLIFAIIVAFVIPEVFSVGMGNASKLNLSI GISIIMILLYVAALYFKLVTHRGVYQPNNAAQTEEEEEPEWSGKVATIVLFAATIVVA YISENLVHTFHSVAEQFGWSELFIGVIIVAIVGNAAEHASAIIMAFKNKMDIAVEIAV GSTLQIAMFVAPVLVICSIFFPTSMPLVFTLPELVAMVSAVLLMIAISNDGDSNWFEG ATLLAAYVIMAIGFFLL*" gene 865205..866260 /gene="chaA" /locus_tag="BSU_07920" /old_locus_tag="BSU07920" promotor_-35 866274..866280 /Source="Nicolas_upshift_promotors" /id="U608" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=931 /SigmaFactorBS="gatcggctttttccttctttaacctgaaaaaatgaTGGATAA caacaaagcgggatGAAAAGACTAAGggaaaatgccatagaaagagtgatatgatgaa a" /listShort="yfkD" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 866295..866306 /Source="Nicolas_upshift_promotors" /id="U608" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=931 /SigmaFactorBS="gatcggctttttccttctttaacctgaaaaaatgaTGGATAA caacaaagcgggatGAAAAGACTAAGggaaaatgccatagaaagagtgatatgatgaa a" /listShort="yfkD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 866299 /Source="Nicolas_upshifts" /id="U608" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=931 /SigmaFactorBS="gatcggctttttccttctttaacctgaaaaaatgaTGGATAA caacaaagcgggatGAAAAGACTAAGggaaaatgccatagaaagagtgatatgatgaa a" /listShort="yfkD" /GFF_Attribute="listLong" CDS 866331..867125 /gene="yfkD" /locus_tag="BSU_07930" /old_locus_tag="BSU07930" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 19543710" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_388674.1" /db_xref="EnsemblGenomes-Gn:BSU07930" /db_xref="EnsemblGenomes-Tr:CAB12622" /db_xref="InterPro:IPR025548" /db_xref="SubtiList:BG12921" /db_xref="UniProtKB/Swiss-Prot:O34579" /translation="MMKKLFHSTLIVLLFFSFFGVQPIHAKKQFKVPNSVASISKENT YPNASQDQPMLQPSKLAKELLDHSEVKIENPHLIKMLNESNISGTPLAVGYRATIFLG KWALGYESNETVANWEYKKINTNRADNRGGKETAEMHYAQEQQYRVKGGLTAKVPNAE DVKSMMMQKAMKKTNLPLAFETVIGAGTKRDQIYKVAPKKIGYLHAYAPAVNEKGKVT YGEVYLVLKGNKRKLVVKNVTSQGIGAWIPVQDHVTFGFQLSSLPR*" gene 866331..867125 /gene="yfkD" /locus_tag="BSU_07930" /old_locus_tag="BSU07930" downshifts 867113 /Source="Nicolas_upshifts" /id="D396" /incds=0 /nref=41 /ntot=100 /MaxReadThrough="0.82657" /MaxDrop="5.7252" /score="28.7014976" /energy="-9.5" /TU="NA" /idTUdmin="U605" /TUdmin=0 /isTUend="TRUE" CDS complement(867164..868006) /gene="mscC" /locus_tag="BSU_07940" /old_locus_tag="BSU07940" /function="16.1: Circulate" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:17665170, 18310427, 19252899" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 17665170, 18310427, 19252899; Product type t: transporter" /codon_start=1 /transl_table=11 /product="mechanosensitive ion channel" /protein_id="NP_388675.1" /db_xref="EnsemblGenomes-Gn:BSU07940" /db_xref="EnsemblGenomes-Tr:CAB12623" /db_xref="GOA:O35043" /db_xref="InterPro:IPR006685" /db_xref="InterPro:IPR010920" /db_xref="InterPro:IPR011014" /db_xref="SubtiList:BG12920" /db_xref="UniProtKB/Swiss-Prot:O35043" /translation="MRMKETLTEIFQNKIVDILLVAVILWIGVFIINRLVQLFFKRTD FIEEKKEKTIESLVRSVTQYTATIGFIFYVISLFVHDFGKILAGAGVAGIVIGFGAQS LIKDVLAGVFLIYERQLHKGDYVTVNNLFNGTVEEIGLRSLQIREWSGKLLTISNGEV RQIENYNIDFMRITESFLISFKEDPDRVYSVLEEACDMLNEELRDSLKRDEFGNPTEP FQIHGITALNKINRGVEFTVKGMVKDDDYFSASLAVRRVLVRQLYQNNVQMLEEAVRI ERTQ*" gene complement(867164..868006) /gene="mscC" /locus_tag="BSU_07940" /old_locus_tag="BSU07940" downshifts complement(867166) /Source="Nicolas_upshifts" /id="D397" /incds=0 /nref=58 /ntot=230 /MaxReadThrough="1.96922" /MaxDrop="4.8789" /score="23.5281308" /energy="-9.8" /TU="NA" /idTUdmin="U609" /TUdmin=1 /isTUend="TRUE" CDS complement(868007..869128) /gene="yfkA" /locus_tag="BSU_07955" /old_locus_tag="BSU07955" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative Fe-S oxidoreductase, radical SAM superfamily" /protein_id="NP_388677.2" /db_xref="EnsemblGenomes-Gn:BSU07955" /db_xref="EnsemblGenomes-Tr:CAB12625" /db_xref="GOA:O34400" /db_xref="InterPro:IPR007197" /db_xref="InterPro:IPR013785" /db_xref="InterPro:IPR014866" /db_xref="InterPro:IPR031004" /db_xref="InterPro:IPR034395" /db_xref="SubtiList:BG12918" /db_xref="UniProtKB/Swiss-Prot:O34400" /translation="MTQNTKLRPITPEFDPWEAYMDVDQYGDMQLTNVEFTTTTLCNM RCEHCAVGYTLQPKDPNALPIDLLLKRLEEIPRLRSISITGGEPMLSLKSVKEYVVPL LKYAHERGVRTQINSNLTLDIERYEWIIPYLDVLHISHNWGTVEDFAEIGFAMMDRKP TFEQRARYFEKMIENSRTLVDAGVMVSAETMLNKRTLPHIEHIHRQITEDMKCQRHEV HPMYPSDFASALESLSLKEMRQAIHRLLDIRDENTWMLFGTLPFYACSPDEDDQKLLR RLRAAKNVTVRNDPDGRSRLNVNIFDGNIIVTDFGDTPPLGNIQTDSLPSAYEKWRET KLAKELSCHCPNVRCLGPNVLVKNSYYQDTDFTKRQARS*" gene complement(868007..869128) /gene="yfkA" /locus_tag="BSU_07955" /old_locus_tag="BSU07955" promotor_-10 complement(869169..869188) /Source="Nicolas_upshift_promotors" /id="U609" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.942057942057942" /psig=1 /xcortree=2517 /SigmaFactorBS="atggtagctcattttttgccgtttttcaatcgccgcgctACT TGcgatcttggcaaatcAGGTCTAAAATTAACTGTTGgcagcgttagtatgcccattt a" /listShort="yfkA, yfkC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(869187) /Source="Nicolas_upshifts" /id="U609" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.942057942057942" /psig=1 /xcortree=2517 /SigmaFactorBS="atggtagctcattttttgccgtttttcaatcgccgcgctACT TGcgatcttggcaaatcAGGTCTAAAATTAACTGTTGgcagcgttagtatgcccattt a" /listShort="yfkA, yfkC" /GFF_Attribute="listLong" promotor_-35 complement(869204..869208) /Source="Nicolas_upshift_promotors" /id="U609" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.942057942057942" /psig=1 /xcortree=2517 /SigmaFactorBS="atggtagctcattttttgccgtttttcaatcgccgcgctACT TGcgatcttggcaaatcAGGTCTAAAATTAACTGTTGgcagcgttagtatgcccattt a" /listShort="yfkA, yfkC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 869216..869223 /Source="Nicolas_upshift_promotors" /id="U610" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.537462537462537" /psig=1 /xcortree=574 /SigmaFactorBS="ctgatttgccaagatcgcaagtagcgcggCGATTGAAaaacg gcaaaaaaTGAGCTACCATAATAAAAAAtgaatggaggaacagaatggggaacgccgt a" /listShort="yfjT, pdaA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 869237..869256 /Source="Nicolas_upshift_promotors" /id="U610" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.537462537462537" /psig=1 /xcortree=574 /SigmaFactorBS="ctgatttgccaagatcgcaagtagcgcggCGATTGAAaaacg gcaaaaaaTGAGCTACCATAATAAAAAAtgaatggaggaacagaatggggaacgccgt a" /listShort="yfjT, pdaA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 869247 /Source="Nicolas_upshifts" /id="U610" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.537462537462537" /psig=1 /xcortree=574 /SigmaFactorBS="ctgatttgccaagatcgcaagtagcgcggCGATTGAAaaacg gcaaaaaaTGAGCTACCATAATAAAAAAtgaatggaggaacagaatggggaacgccgt a" /listShort="yfjT, pdaA" /GFF_Attribute="listLong" CDS 869273..869458 /gene="yfjT" /locus_tag="BSU_07970" /old_locus_tag="BSU07970" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 22720735" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_388678.1" /db_xref="EnsemblGenomes-Gn:BSU07970" /db_xref="EnsemblGenomes-Tr:CAB12626" /db_xref="SubtiList:BG12916" /db_xref="UniProtKB/Swiss-Prot:O35041" /translation="MGNAVNNKDQQIDYLKNRLDMFMNVIDSLDPEATDVEDIDRLIS MLDDLEAKYERFKKDWE*" gene 869273..869458 /gene="yfjT" /locus_tag="BSU_07970" /old_locus_tag="BSU07970" downshifts 869437 /Source="Nicolas_upshifts" /id="D398" /incds=0 /nref=15 /ntot=177 /MaxReadThrough="3.03457" /MaxDrop="3.24661" /score="14.1645187" /energy="-6.4" /TU="U610" /idTUdmin="U610" /TUdmin="-559" /isTUend="FALSE" promotor_-35 869501..869507 /Source="Nicolas_upshift_promotors" /id="U611" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.95004995004995" /psig="0.95004995004995" /xcortree=930 /SigmaFactorBS="gaataaaaccgcgtgcccgccgcggtttttttattggcataa agcaacAGTATAAaacaaagtctctatCTGTAAAATAAGaaaaaatgcagaaggagcg c" /listShort="pdaA" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 869513 /Source="Nicolas_upshifts" /id="U611" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.95004995004995" /psig="0.95004995004995" /xcortree=930 /SigmaFactorBS="gaataaaaccgcgtgcccgccgcggtttttttattggcataa agcaacAGTATAAaacaaagtctctatCTGTAAAATAAGaaaaaatgcagaaggagcg c" /listShort="pdaA" /GFF_Attribute="listLong" promotor_-10 869522..869533 /Source="Nicolas_upshift_promotors" /id="U611" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.95004995004995" /psig="0.95004995004995" /xcortree=930 /SigmaFactorBS="gaataaaaccgcgtgcccgccgcggtttttttattggcataa agcaacAGTATAAaacaaagtctctatCTGTAAAATAAGaaaaaatgcagaaggagcg c" /listShort="pdaA" /GFF_Attribute="listLong" /label="promotor_-10" CDS 869559..870350 /gene="pdaA" /locus_tag="BSU_07980" /old_locus_tag="BSU07980" /EC_number="3.5.1.-" /function="16.11: Scavenge (Catabolism)" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:14679227, 15687192" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 14679227, 15687192; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="exported peptidoglycan N-acetylmuramic acid deacetylase" /protein_id="NP_388679.1" /db_xref="EnsemblGenomes-Gn:BSU07980" /db_xref="EnsemblGenomes-Tr:CAB12627" /db_xref="GOA:O34928" /db_xref="InterPro:IPR002509" /db_xref="InterPro:IPR011330" /db_xref="InterPro:IPR014235" /db_xref="PDB:1NY1" /db_xref="PDB:1W17" /db_xref="PDB:1W1A" /db_xref="PDB:1W1B" /db_xref="SubtiList:BG12915" /db_xref="UniProtKB/Swiss-Prot:O34928" /translation="MKWMCSICCAAVLLAGGAAQAEAVPNEPINWGFKRSVNHQPPDA GKQLNSLIEKYDAFYLGNTKEKTIYLTFDNGYENGYTPKVLDVLKKHRVTGTFFVTGH FVKDQPQLIKRMSDEGHIIGNHSFHHPDLTTKTADQIQDELDSVNEEVYKITGKQDNL YLRPPRGVFSEYVLKETKRLGYQTVFWSVAFVDWKINNQKGKKYAYDHMIKQAHPGAI YLLHTVSRDNAEALDDAITDLKKQGYTFKSIDDLMFEKEMRLPSL*" gene 869559..870350 /gene="pdaA" /locus_tag="BSU_07980" /old_locus_tag="BSU07980" downshifts 870348 /Source="Nicolas_upshifts" /id="D399" /incds=0 /nref=1 /ntot=36 /MaxReadThrough="2.12067" /MaxDrop="3.4013" /score="14.4741934" /energy="-10.2" /TU="NA" /idTUdmin="U611" /TUdmin=22 /isTUend="TRUE" CDS complement(870388..871248) /gene="yfjR" /locus_tag="BSU_07990" /old_locus_tag="BSU07990" /EC_number="1.1.1.-" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 20512483; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative beta-hydroxyacid dehydrogenase" /protein_id="NP_388680.2" /db_xref="EnsemblGenomes-Gn:BSU07990" /db_xref="EnsemblGenomes-Tr:CAB12628" /db_xref="GOA:O34969" /db_xref="InterPro:IPR006115" /db_xref="InterPro:IPR008927" /db_xref="InterPro:IPR013328" /db_xref="InterPro:IPR015815" /db_xref="InterPro:IPR029154" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG12914" /db_xref="UniProtKB/Swiss-Prot:O34969" /translation="MKIAVIGLGNMGQPIARNVLQAGYELTVYNRTKQKTEDLVTEGA QAADTPRLAAKSADIVITMLADDDSVSTVTFGEDGLLEGLAENGIHISMSTISVEFSE KLAAAHAEKGQFFLAAPVLGRPDAAAKAALRIITAGPAEAKQAAKPLLDSLSQQIFDV GEESKTANAAKISINFLLVSMLEALSESFLMMEKYGLEQKQFLEIASALFGSPVYQNY GTIMAEQKFEPAGFKMSLGLKDTNLALAAAKRVSANLPLAELAKSHFESGIEKGFGDL DWAALIKCIK*" gene complement(870388..871248) /gene="yfjR" /locus_tag="BSU_07990" /old_locus_tag="BSU07990" downshifts complement(870402) /Source="Nicolas_upshifts" /id="D400" /incds=0 /nref=15 /ntot=193 /MaxReadThrough="2.61589" /MaxDrop="3.98341" /score="-1.3382901" /energy="-12.1" /TU="NA" /idTUdmin="U612" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(871268..871287) /Source="Nicolas_upshift_promotors" /id="U612" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.834165834165834" /psig=1 /xcortree=1961 /SigmaFactorBS="agcgagcagctgttcttttttgttgtaagccgatcgCTATgc atattctgttcatATTGTTTATAATGGAAAAAAtattcagggagtgattagattgaaa a" /listShort="yfjR" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(871282) /Source="Nicolas_upshifts" /id="U612" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.834165834165834" /psig=1 /xcortree=1961 /SigmaFactorBS="agcgagcagctgttcttttttgttgtaagccgatcgCTATgc atattctgttcatATTGTTTATAATGGAAAAAAtattcagggagtgattagattgaaa a" /listShort="yfjR" /GFF_Attribute="listLong" promotor_-35 complement(871303..871306) /Source="Nicolas_upshift_promotors" /id="U612" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.834165834165834" /psig=1 /xcortree=1961 /SigmaFactorBS="agcgagcagctgttcttttttgttgtaagccgatcgCTATgc atattctgttcatATTGTTTATAATGGAAAAAAtattcagggagtgattagattgaaa a" /listShort="yfjR" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(871347..872306) /gene="yfjQ" /locus_tag="BSU_08000" /old_locus_tag="BSU08000" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 14563871, 24415722; Product type t: transporter" /codon_start=1 /transl_table=11 /product="divalent cation (octahedral coordination) transporter" /protein_id="NP_388681.1" /db_xref="EnsemblGenomes-Gn:BSU08000" /db_xref="EnsemblGenomes-Tr:CAB12629" /db_xref="GOA:O31543" /db_xref="InterPro:IPR002523" /db_xref="InterPro:IPR004488" /db_xref="SubtiList:BG12913" /db_xref="UniProtKB/Swiss-Prot:O31543" /translation="MINITAITTEHQLLKNIPIERVEQPDIAWYWVDFYGPEDTETAL LRDFFHFHPLAIEDCFQHMQRPKLDHYDGYRFYVIHALNKETLETEEVDIFQGEKFVV TFHLHETPGIAKVRERLYASPDILKKGPGHISYMIMDQLVDEYFPLVYKIEDRLNEIE ESRPHKTYGTLMNEVFDLRTDLLHLRRTIIPMRDLLYRILSLDHVKEQRETKAYFSDI YDHLLKLSEIVESNRDMTSDLRDSYVTLNSNRMNAIMMTLTIVSTIFIPLTFIAGVYG MNFDFMPELHWKYGYFAVLGLMAALVIGMLIWFVHKGWFNIFK*" gene complement(871347..872306) /gene="yfjQ" /locus_tag="BSU_08000" /old_locus_tag="BSU08000" downshifts complement(871370) /Source="Nicolas_upshifts" /id="D401" /incds=0 /nref=137 /ntot=224 /MaxReadThrough="2.29296" /MaxDrop="4.2496" /score="10.2736001" /energy="-7.5" /TU="NA" /idTUdmin="U613" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(872317..872336) /Source="Nicolas_upshift_promotors" /id="U613" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.888111888111888" /psig="0.993006993006993" /xcortree=1816 /SigmaFactorBS="tggaattaggcagagagtaccgtatACTTttctcataaagac cgCATGATATAATGGCAGGTGGagggttgtttatgatcaacattaccgcaatcacaac a" /listShort="yfjQ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(872320) /Source="Nicolas_upshifts" /id="U613" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.888111888111888" /psig="0.993006993006993" /xcortree=1816 /SigmaFactorBS="tggaattaggcagagagtaccgtatACTTttctcataaagac cgCATGATATAATGGCAGGTGGagggttgtttatgatcaacattaccgcaatcacaac a" /listShort="yfjQ" /GFF_Attribute="listLong" promotor_-35 complement(872352..872355) /Source="Nicolas_upshift_promotors" /id="U613" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.888111888111888" /psig="0.993006993006993" /xcortree=1816 /SigmaFactorBS="tggaattaggcagagagtaccgtatACTTttctcataaagac cgCATGATATAATGGCAGGTGGagggttgtttatgatcaacattaccgcaatcacaac a" /listShort="yfjQ" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 872367..872371 /Source="Nicolas_upshift_promotors" /id="U614" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.832167832167832" /psig="0.999000999001" /xcortree=2271 /SigmaFactorBS="atgcggtctttatgagaaaagtatacggtactcTCTGCctaa ttccagcggCATGTTATACTGAACAAAAAcggaaaaaagggtggatctcatgtggaag g" /listShort="yfjP, S277, yfjO" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 872385..872404 /Source="Nicolas_upshift_promotors" /id="U614" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.832167832167832" /psig="0.999000999001" /xcortree=2271 /SigmaFactorBS="atgcggtctttatgagaaaagtatacggtactcTCTGCctaa ttccagcggCATGTTATACTGAACAAAAAcggaaaaaagggtggatctcatgtggaag g" /listShort="yfjP, S277, yfjO" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 872394 /Source="Nicolas_upshifts" /id="U614" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.832167832167832" /psig="0.999000999001" /xcortree=2271 /SigmaFactorBS="atgcggtctttatgagaaaagtatacggtactcTCTGCctaa ttccagcggCATGTTATACTGAACAAAAAcggaaaaaagggtggatctcatgtggaag g" /listShort="yfjP, S277, yfjO" /GFF_Attribute="listLong" CDS 872425..873288 /gene="yfjP" /locus_tag="BSU_08010" /old_locus_tag="BSU08010" /EC_number="3.2.2.21" /function="16.8: Protect" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative DNA-3-methyladenine glycosylase" /protein_id="NP_388682.1" /db_xref="EnsemblGenomes-Gn:BSU08010" /db_xref="EnsemblGenomes-Tr:CAB12630" /db_xref="GOA:O31544" /db_xref="InterPro:IPR003265" /db_xref="InterPro:IPR011257" /db_xref="InterPro:IPR023170" /db_xref="SubtiList:BG12912" /db_xref="UniProtKB/Swiss-Prot:O31544" /translation="MWKEKVSVTPPYHFDRVLDRLSLDPLNAVDREAREVRVPIRNQA GDVCIVKVQALGHAGEPEFLVSGETDQGEMMKEIKRIFQWENHLQHVLDHFSKTSLSA IFEEHAGTPLVLDYSVYNCMMKCIIHQQLNLSFAYTLTERFVHAFGEQKDGVWCYPKP ETIAELDYQDLRDLQFSMRKAEYTIDTSRMIAEGTLSLSELPHMADEDIMKKLIKIRG IGPWTVQNVLMFGLGRPNLFPLADIGLQNAIKRHFQLDDKPAKDVMLAMSKEWEPYLS YASLYLWRSIE*" gene 872425..873288 /gene="yfjP" /locus_tag="BSU_08010" /old_locus_tag="BSU08010" S_feature 873289..873401 /Source="Nicolas_S_feature" /locus_tag="new_873289_873401" /HighExp="BC, M40t90, LBGtran, C90, M9-stat, M0t90, Lbtran, Sw, M40t45, B60" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S277" CDS 873402..874802 /gene="yfjO" /locus_tag="BSU_08020" /old_locus_tag="BSU08020" /EC_number="2.1.1.-" /function="16.8: Protect" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative RNA methyltransferase" /protein_id="NP_388683.1" /db_xref="EnsemblGenomes-Gn:BSU08020" /db_xref="EnsemblGenomes-Tr:CAB12631" /db_xref="GOA:O31545" /db_xref="InterPro:IPR001566" /db_xref="InterPro:IPR002792" /db_xref="InterPro:IPR010280" /db_xref="InterPro:IPR012340" /db_xref="InterPro:IPR029063" /db_xref="InterPro:IPR030390" /db_xref="InterPro:IPR030391" /db_xref="SubtiList:BG12911" /db_xref="UniProtKB/Swiss-Prot:O31545" /translation="MNQQKKQAPVELKVGQTFPLTIKRLGINGEGVGYFKKKVVFVPG ALPGEEVVVQATKVQPKFSEGRIKKIRKASEHRVAPPCPVYEQCGGCQLQHLAYSQQL REKRDIVIQSLERHTKFKVENMEIKETIGMDNPWNYRNKSQFQIGRSQSGSIIAGLYG LDSHDIVPIKDCIVQHPATNKTTGIVRRILEDFNVSVYNERKRKGDVRTIVTRVGFET GEVQVVLVTAKETLPHKEEIVKAIQKRLPEVKSIIQNVNGAKTSVIFGEKTKQLAGKT VIQEVLGDVSFELSARAFFQLNPEQTVKLYDEVKKAAQLTGKEKVVDAYCGVGTIGMW VADGAKEVRGMDVIKESIDDAKKNAKKHGMANATYVTGTAEHWLPKWTKEGFRPDVVI VDPPRTGCDSTFLDTIKKVKPKRFVYVSCNPSTLAKDLQTLSKDYRVDYIQPVDMFPQ TAHVEAVARLVLKSSN*" gene 873402..874802 /gene="yfjO" /locus_tag="BSU_08020" /old_locus_tag="BSU08020" downshifts 874814 /Source="Nicolas_upshifts" /id="D402" /incds=0 /nref=198 /ntot=251 /MaxReadThrough="1.18186" /MaxDrop="5.19313" /score="11.8630961" /energy="-12.6" /TU="NA" /idTUdmin="U614" /TUdmin=0 /isTUend="TRUE" promotor_-35 875108..875115 /Source="Nicolas_upshift_promotors" /id="U615" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.98901098901099" /psig=1 /xcortree=2924 /SigmaFactorBS="tagatgtattttcataatttgtaaaattataTATTGACTtgc agttattacgtgTGAAATATTGATGATAGGAAtataaggaaagtatggcgtatatcat t" /listShort="S278, yfzA, S279" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 875131..875150 /Source="Nicolas_upshift_promotors" /id="U615" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.98901098901099" /psig=1 /xcortree=2924 /SigmaFactorBS="tagatgtattttcataatttgtaaaattataTATTGACTtgc agttattacgtgTGAAATATTGATGATAGGAAtataaggaaagtatggcgtatatcat t" /listShort="S278, yfzA, S279" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 875137 /Source="Nicolas_upshifts" /id="U615" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.98901098901099" /psig=1 /xcortree=2924 /SigmaFactorBS="tagatgtattttcataatttgtaaaattataTATTGACTtgc agttattacgtgTGAAATATTGATGATAGGAAtataaggaaagtatggcgtatatcat t" /listShort="S278, yfzA, S279" /GFF_Attribute="listLong" S_feature 875144..875427 /Source="Nicolas_S_feature" /locus_tag="new_875144_875427" /HighExp="M9-stat, T1.30H, T0.30H, T2.0H, LoTm, T3.0H, T3.30H, T1.0H, T2.30H, T4.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.69102300000000005" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S278" CDS 875428..875694 /gene="yfzA" /locus_tag="BSU_08029" /old_locus_tag="BSU08029" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="YP_003097694.1" /db_xref="EnsemblGenomes-Gn:BSU08029" /db_xref="EnsemblGenomes-Tr:CAX52581" /db_xref="GOA:C0H3X6" /db_xref="InterPro:IPR025627" /db_xref="UniProtKB/Swiss-Prot:C0H3X6" /translation="MDKVYKRSWFQTFLAFLVSQLYFNFVELTGWGPKYREMNGFPAN IVELDFFQTYLSFYDNPWFNIITVFLGVFTIIQIITGITKDIRN*" gene 875428..875694 /gene="yfzA" /locus_tag="BSU_08029" /old_locus_tag="BSU08029" promotor_-10 complement(875642..875661) /Source="Nicolas_upshift_promotors" /id="U616" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.936063936063936" /psig=1 /xcortree=2926 /SigmaFactorBS="taaataaggcatcagaagttattgctttaatttcgaatatcC TTTgttatccctgtaatTATTTGTATAATAGTGAAAActcccaagaaaacagtaataa t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(875660) /Source="Nicolas_upshifts" /id="U616" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.936063936063936" /psig=1 /xcortree=2926 /SigmaFactorBS="taaataaggcatcagaagttattgctttaatttcgaatatcC TTTgttatccctgtaatTATTTGTATAATAGTGAAAActcccaagaaaacagtaataa t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(875676..875679) /Source="Nicolas_upshift_promotors" /id="U616" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.936063936063936" /psig=1 /xcortree=2926 /SigmaFactorBS="taaataaggcatcagaagttattgctttaatttcgaatatcC TTTgttatccctgtaatTATTTGTATAATAGTGAAAActcccaagaaaacagtaataa t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" S_feature 875695..876176 /Source="Nicolas_S_feature" /locus_tag="new_875695_876176" /HighExp="G180, Paraq, H2O2, G135, Oxctl, G150, C30, LoTm, S8, M9-stat" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S279" promotor_-35 876147..876150 /Source="Nicolas_upshift_promotors" /id="U617" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.591408591408591" /psig=1 /xcortree=2598 /SigmaFactorBS="atcttcaataacagggcaattattttgcgTTGGtaatatgga gaactcaTATGATATTCTATTTAGGTTggaatcctttttatccaaaaagttcaaaagc a" /listShort="S280, dusC, S281, yfjM, yfjL" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 876167..876186 /Source="Nicolas_upshift_promotors" /id="U617" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.591408591408591" /psig=1 /xcortree=2598 /SigmaFactorBS="atcttcaataacagggcaattattttgcgTTGGtaatatgga gaactcaTATGATATTCTATTTAGGTTggaatcctttttatccaaaaagttcaaaagc a" /listShort="S280, dusC, S281, yfjM, yfjL" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 876178..876425 /Source="Nicolas_S_feature" /locus_tag="new_876178_876425" /HighExp="H2O2, G180, Paraq, G150, G135, Oxctl, dia15, LBGstat, LBGexp, Diami" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S280" upshifts 876178 /Source="Nicolas_upshifts" /id="U617" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.591408591408591" /psig=1 /xcortree=2598 /SigmaFactorBS="atcttcaataacagggcaattattttgcgTTGGtaatatgga gaactcaTATGATATTCTATTTAGGTTggaatcctttttatccaaaaagttcaaaagc a" /listShort="S280, dusC, S281, yfjM, yfjL" /GFF_Attribute="listLong" CDS 876426..877403 /gene="dusC" /locus_tag="BSU_08030" /old_locus_tag="BSU08030" /EC_number="1.-.-.-" /function="16.2: Construct biomass (Anabolism)" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 11983710, 25902496; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="tRNA-dihydrouridine synthase 2" /protein_id="NP_388684.1" /db_xref="EnsemblGenomes-Gn:BSU08030" /db_xref="EnsemblGenomes-Tr:CAB12632" /db_xref="GOA:O31546" /db_xref="InterPro:IPR001269" /db_xref="InterPro:IPR013785" /db_xref="InterPro:IPR018517" /db_xref="InterPro:IPR024036" /db_xref="InterPro:IPR035587" /db_xref="SubtiList:BG12910" /db_xref="UniProtKB/Swiss-Prot:O31546" /translation="MTENFWRELPRPFFVLAPMEDVTDVVFRHVVSEAGRPDVFFTEF TNSESYCHPDGKDSVRGRLTFTEDEQPIVAHIWGDKPENFRKMSIGMAELGFKGLDIN MGCPVPNVAGNGKGSGLICRPAVAAELIQAAKAGGLPVSVKTRLGYTDVDEWREWLTH ILKQDIANLSIHLRTRAEMSKVDAHWELIPEIKKLRDEVAPDTLLTINGDIPDRQTGL KLAEQYGVDGIMIGRGIFTNPFAFEKEPKEHSSKELLDLLRLHLDLHDEYSKEEARPY KPLPRFFKIYLRGFRGASELRNQCMNTKSTDEVRALLDDFERKYLDGIE*" gene 876426..877403 /gene="dusC" /locus_tag="BSU_08030" /old_locus_tag="BSU08030" S_feature 877404..877496 /Source="Nicolas_S_feature" /locus_tag="new_877404_877496" /HighExp="G135, G180, Paraq, G150, H2O2, LBGexp, aero, dia0, Oxctl, dia15" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S281" downshifts 877453 /Source="Nicolas_upshifts" /id="D403" /incds=0 /nref=86 /ntot=218 /MaxReadThrough="3.30163" /MaxDrop="4.0519" /score="11.8630961" /energy="-12.6" /TU="U617" /idTUdmin="U618" /TUdmin="-1211" /isTUend="FALSE" promotor_-35 877537..877543 /Source="Nicolas_upshift_promotors" /id="U618" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.994005994005994" /psig="0.999000999001" /xcortree=3192 /SigmaFactorBS="gtacgcagcttttactcagcctgtcttttctctAATTTATtg taagaaaatAATGGTATATTTAGTGGAGAtatcatataaagggggagaggaaaatgaa a" /listShort="yfjM, yfjL" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 877555..877574 /Source="Nicolas_upshift_promotors" /id="U618" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.994005994005994" /psig="0.999000999001" /xcortree=3192 /SigmaFactorBS="gtacgcagcttttactcagcctgtcttttctctAATTTATtg taagaaaatAATGGTATATTTAGTGGAGAtatcatataaagggggagaggaaaatgaa a" /listShort="yfjM, yfjL" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 877564 /Source="Nicolas_upshifts" /id="U618" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.994005994005994" /psig="0.999000999001" /xcortree=3192 /SigmaFactorBS="gtacgcagcttttactcagcctgtcttttctctAATTTATtg taagaaaatAATGGTATATTTAGTGGAGAtatcatataaagggggagaggaaaatgaa a" /listShort="yfjM, yfjL" /GFF_Attribute="listLong" CDS 877599..878051 /gene="yfjM" /locus_tag="BSU_08040" /old_locus_tag="BSU08040" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_388685.1" /db_xref="EnsemblGenomes-Gn:BSU08040" /db_xref="EnsemblGenomes-Tr:CAB12633" /db_xref="SubtiList:BG12909" /db_xref="UniProtKB/Swiss-Prot:O31547" /translation="MKRLCIIPCGKKKIWDVQPDAGPVRAEDAYLSPFHQACERYAKT FFDEWVILSAKHGFLRPDDLVSGNYDVTFGTGHPEIMTADELRRQFHEKGFSDIEELV MLGGKKYRSVLNAVIGEHQHISWPLSSYKGIGYMLQALNRAVEEKHEL*" gene 877599..878051 /gene="yfjM" /locus_tag="BSU_08040" /old_locus_tag="BSU08040" CDS 878081..878770 /gene="yfjL" /locus_tag="BSU_08050" /old_locus_tag="BSU08050" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_388686.1" /db_xref="EnsemblGenomes-Gn:BSU08050" /db_xref="EnsemblGenomes-Tr:CAB12634" /db_xref="InterPro:IPR020523" /db_xref="SubtiList:BG11034" /db_xref="UniProtKB/Swiss-Prot:P40773" /translation="MKKLVFGLLAIVLFGCGLYIYHVWFGDPFSKNAAEQKLVSYVKQ TYPKKEIKITNGVYNAKTSEYVFEATSQSHRYPMCTKGFLHPKVTCDGIEEAYTESVA KHVNEEATKAIEADLKKAVPRFIKADAALSIENGQFTLDTKWNKKLAEKAPMSMTIQL DASGLSKTDAAKMAETVRKTLNEKGYTYSNGTIDCMQKDGDGGIGYVKYSIDFLSKAA IQSNDAEELGS*" gene 878081..878770 /gene="yfjL" /locus_tag="BSU_08050" /old_locus_tag="BSU08050" downshifts 878775 /Source="Nicolas_upshifts" /id="D404" /incds=0 /nref=31 /ntot=205 /MaxReadThrough="0.02745" /MaxDrop="3.61164" /score="23.9796437" /energy="-9" /TU="NA" /idTUdmin="U617" /TUdmin=1 /isTUend="TRUE" misc_feature 878947..878965 /Source="Nicolas_upshift_promotors" /id="U619" /multdbtbs="SigL" /comp="M18" /sig="SigL" /pcomp="0.878121878121878" /psig="0.878121878121878" /xcortree=351 /SigmaFactorBS="caaactgtctccaaagtgaagatgagaagactgattttacgg gctcaaaagacTGGCACACTTCTTGCATTTataatggtgaaccctaaatagaaggagg c" /listShort="acoA, acoB, acoC, acoL, acoR, sspH" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 878954 /Source="Nicolas_upshifts" /id="U619" /multdbtbs="SigL" /comp="M18" /sig="SigL" /pcomp="0.878121878121878" /psig="0.878121878121878" /xcortree=351 /SigmaFactorBS="caaactgtctccaaagtgaagatgagaagactgattttacgg gctcaaaagacTGGCACACTTCTTGCATTTataatggtgaaccctaaatagaaggagg c" /listShort="acoA, acoB, acoC, acoL, acoR, sspH" /GFF_Attribute="listLong" CDS 879002..880003 /gene="acoA" /locus_tag="BSU_08060" /old_locus_tag="BSU08060" /EC_number="1.1.1.303" /EC_number="2.3.1.190" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:10368162, 11274109, 22714279" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10368162, 11274109, 22714279; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="acetoin dehydrogenase E1 component (TPP-dependent alpha subunit)" /protein_id="NP_388687.1" /db_xref="EnsemblGenomes-Gn:BSU08060" /db_xref="EnsemblGenomes-Tr:CAB12635" /db_xref="GOA:O31404" /db_xref="InterPro:IPR001017" /db_xref="InterPro:IPR029061" /db_xref="SubtiList:BG12558" /db_xref="UniProtKB/Swiss-Prot:O31404" /translation="MKLLKREGLSLTEEKALWMYQKMLEIRGFEDKVHELFAQGVLPG FVHLYAGEEAVAVGVCAHLHDGDSITSTHRGHGHCIAKGCDLDGMMAEIFGKATGLCK GKGGSMHIADLDKGMLGANGIVGGGFTLACGSALTAKYKQTKNVSVCFFGDGANNQGT FHEGLNLAAVWNLPVVFVAENNGYGEATPFEYASACDSIADRAAAYNMPGVTVDGKDI LAVYQAAEEAIERARNGGGPSLIECMTYRNYGHFEGDAQTYKTKDERVEHLEEKDAIQ GFKNYLLKETDANKLSDIEQRVSESIEKAVSFSEDSPYPKDSELLTDVYVSYEKGGM* " gene 879002..880003 /gene="acoA" /locus_tag="BSU_08060" /old_locus_tag="BSU08060" CDS 880007..881035 /gene="acoB" /locus_tag="BSU_08070" /old_locus_tag="BSU08070" /EC_number="1.1.1.303" /EC_number="2.3.1.190" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:11274109, 10368162" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11274109, 10368162; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="acetoin dehydrogenase E1 component (TPP-dependent beta subunit)" /protein_id="NP_388688.1" /db_xref="EnsemblGenomes-Gn:BSU08070" /db_xref="EnsemblGenomes-Tr:CAB12636" /db_xref="GOA:O34591" /db_xref="InterPro:IPR005475" /db_xref="InterPro:IPR009014" /db_xref="InterPro:IPR029061" /db_xref="InterPro:IPR033248" /db_xref="SubtiList:BG12559" /db_xref="UniProtKB/Swiss-Prot:O34591" /translation="MARVISMSDAINEAMKLAMRKDENVLLIGEDVAGGAAVDHLQDD EAWGGVLGVTKGLVQEFGRTRVLDTPISEAGYMGAAMAAASTGLRPIAELMFNDFIGT CFDQVINQGAKFRYMFGGKAQVPITVRTTYGAGFRAAAQHSQSLYGLFTSIPGLKTVV PSNPYDAKGLLLAAIEDNDPVFFFEDKTSYNMKGEVPEDYYTIPLGKADIKREGNDVT LFAVGKQVNTALEAAAQLSERGIEAEVLDPRSLSPLDEDAIFTSLEKTNRLIIIDEAN PRCSIATDIAALVADKGFDLLDAPIKRITAPHTPVPFSPVLEDQYLPTPDKIVSVTLE LLGEPALN*" gene 880007..881035 /gene="acoB" /locus_tag="BSU_08070" /old_locus_tag="BSU08070" CDS 881049..882245 /gene="acoC" /locus_tag="BSU_08080" /old_locus_tag="BSU08080" /EC_number="2.3.1.12" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:10368162, 11274109" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10368162, 11274109; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="acetoin dehydrogenase E2 component (dihydrolipoamide acetyltransferase)" /protein_id="NP_388689.1" /db_xref="EnsemblGenomes-Gn:BSU08080" /db_xref="EnsemblGenomes-Tr:CAB12637" /db_xref="GOA:O31550" /db_xref="InterPro:IPR000089" /db_xref="InterPro:IPR001078" /db_xref="InterPro:IPR004167" /db_xref="InterPro:IPR011053" /db_xref="InterPro:IPR036625" /db_xref="SubtiList:BG12560" /db_xref="UniProtKB/Swiss-Prot:O31550" /translation="MAVKVVMPKLGMAMKQGEVSIWNKKVGDPVEKGESIASIQSEKI EMEIEAPEKGTLIDIKVKEGEEVPPGTAICYIGDANESVQEEAGAPVAEDNMPQAVQP VKQENKPAASKKDRMKISPVARKIAEKAGLDLKQLKGTGPGGRIVKDDVTKALAEQKK DQAKPVSEQKAQEIPVTGMRKVIAARMQESLANSAQLTITMKADITKLATLQKQLSPT AEERYGTKLTITHFVSRAAVLALQAHPVLNSFYQNERIITHPHVHLGMAVALENGLVV PVIRHAEKLSLIELAQSISENAKKAREGRAGSEELQGSTFSITNLGAFGVEHFTPILN PPETGILGIGASYDTPVYQGEEIVRSTILPLSLTFDHRACDGAPAAAFLKAMKTYLEE PAALIL*" gene 881049..882245 /gene="acoC" /locus_tag="BSU_08080" /old_locus_tag="BSU08080" downshifts complement(881050) /Source="Nicolas_upshifts" /id="D405" /incds=0 /nref=8 /ntot=46 /MaxReadThrough="0.481579999999999" /MaxDrop="4.16582" /score="-0.0231058321" /energy="-9.9" /TU="NA" /idTUdmin="U623" /TUdmin=4796 /isTUend="FALSE" CDS 882266..883642 /gene="acoL" /locus_tag="BSU_08090" /old_locus_tag="BSU08090" /EC_number="1.8.1.4" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:11274109, 22720735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11274109, 22720735; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="acetoin dehydrogenase E3 component (dihydrolipoamide dehydrogenase)" /protein_id="NP_388690.1" /db_xref="EnsemblGenomes-Gn:BSU08090" /db_xref="EnsemblGenomes-Tr:CAB12638" /db_xref="GOA:O34324" /db_xref="InterPro:IPR001100" /db_xref="InterPro:IPR004099" /db_xref="InterPro:IPR006258" /db_xref="InterPro:IPR012999" /db_xref="InterPro:IPR016156" /db_xref="InterPro:IPR023753" /db_xref="InterPro:IPR036188" /db_xref="SubtiList:BG12561" /db_xref="UniProtKB/Swiss-Prot:O34324" /translation="MTLAIIGGGPAGYAAAVSAAQQGRNVLLIDKGKLGGTCLNEGCI PTKSLLESANVLDKIKHADSFGIELPAGAISVDWSKMQSRKQQVVSQLVQGVQYLMKK NQIQVVKGTASFLSERKLLIEGENGKEIREADQVLIASGSEPIELPFAPFDGEWILDS KDALSLSEIPSSLVIVGGGVIGCEYAGLFARLGSQVTIIETADRLIPAEDEDIARLFQ EKLEEDGVEVHTSSRLGRVDQTAKTAIWKSGQREFKTKADYVLVAIGRKPRLDGLQLE QAGVDFSPKGIPVNGHMQTNVPHIYACGDAIGGIQLAHAAFHEGIIAASHASGRDVKI NEKHVPRCIYTSPEIACIGMTERQARSIYGDVKIGEFSFSANGKALIKQQAEGKVKIM AEPEFGEIVGVSMIGPDVTELIGQAAAIMNGEMTADMAEHFIAAHPTLSETLHEALLS TIGLAVHA*" gene 882266..883642 /gene="acoL" /locus_tag="BSU_08090" /old_locus_tag="BSU08090" downshifts 883636 /Source="Nicolas_upshifts" /id="D406" /incds=0 /nref=27 /ntot=56 /MaxReadThrough="5.75671" /MaxDrop="5.6153" /score="27.0133719" /energy="-14.7" /TU="U619" /idTUdmin="U619" /TUdmin="-2156" /isTUend="FALSE" promotor_-35 883689..883696 /Source="Nicolas_upshift_promotors" /id="U620" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.57942057942058" /psig=1 /xcortree=368 /SigmaFactorBS="ggcgcatggatataaggcgcctgcttttttatTGTTGAAAgc gctttattttTCCCCTACAATAGATGAAAAcggcgtgtaagggaggagcgatcaagga a" /listShort="acoR, sspH" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 883709..883728 /Source="Nicolas_upshift_promotors" /id="U620" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.57942057942058" /psig=1 /xcortree=368 /SigmaFactorBS="ggcgcatggatataaggcgcctgcttttttatTGTTGAAAgc gctttattttTCCCCTACAATAGATGAAAAcggcgtgtaagggaggagcgatcaagga a" /listShort="acoR, sspH" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 883717 /Source="Nicolas_upshifts" /id="U620" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.57942057942058" /psig=1 /xcortree=368 /SigmaFactorBS="ggcgcatggatataaggcgcctgcttttttatTGTTGAAAgc gctttattttTCCCCTACAATAGATGAAAAcggcgtgtaagggaggagcgatcaagga a" /listShort="acoR, sspH" /GFF_Attribute="listLong" CDS 883758..885575 /gene="acoR" /locus_tag="BSU_08100" /old_locus_tag="BSU08100" /experiment="publication(s) with functional evidences, PMID:11274109, 16944132" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11274109, 16944132; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator (AcoR-acetoin)" /protein_id="NP_388691.1" /db_xref="EnsemblGenomes-Gn:BSU08100" /db_xref="EnsemblGenomes-Tr:CAB12639" /db_xref="GOA:O31551" /db_xref="InterPro:IPR002078" /db_xref="InterPro:IPR002197" /db_xref="InterPro:IPR003018" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR009057" /db_xref="InterPro:IPR025944" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR029016" /db_xref="SubtiList:BG11790" /db_xref="UniProtKB/Swiss-Prot:O31551" /translation="MNSVPNDLQTWKRFVKDGVLDEARLRKRIAESWHRCKKAEVNPY LEKGPKVLQQTELDQQSKKHSFFLTTAKPYLEKLLPAIKEMEMMALLIDSDGVVLALD GHPRALYEAKRINFVEGACWTETAVGTNAIGTALHISEPVAIQGSEHYSIASHLWNCS AAPIHHEDGSLAGVIDISCPAAGAHPHMLGIATAIAYAAERELAAKSREKELELISRF GERAASSVPMVLCNTKQHIISASMPIRTSMPDWQGRHLYELKERGYSIENAVTIGDGG TCFYLSEQKKKKAFRFNGVIGQSGRSQAMLMHLERAAATDASVCLSGETGTGKEVAAR ALHENSERRHGPFVAVNCGAIPSDLIESELFGYAEGAFTGAKRNGYKGAFQKANQGTL FLDEIGEISHSMQVALLRVLQERKITPIGGTKEIPVDIRVIAATHCDLRELAENGKIR EDLFYRLHVYPIELPPLRDRTEDIPDLFEYYKQKNHWPGDLPSDFCNVLKQWKWPGNI RELFNVFERLSIRFPDGRLRDESLPALLEAAGLPASSAEKKPAAAGVLTFREQIQKDM MIKALESAKGNVSQAAKISGIPRSTFYKRLKKFNLSAES*" gene 883758..885575 /gene="acoR" /locus_tag="BSU_08100" /old_locus_tag="BSU08100" promotor_-35 885576..885582 /Source="Nicolas_upshift_promotors" /id="U621" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp="0.995004995004995" /psig="0.995004995004995" /xcortree=916 /SigmaFactorBS="tacaaacgcctgaaaaaattcaacttgtccgctgaatcataa AGCATACttccttcaggaaatGGAAACGTTATGtattgaaggagggtgttacgatgaa t" /listShort="sspH" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 885594 /Source="Nicolas_upshifts" /id="U621" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp="0.995004995004995" /psig="0.995004995004995" /xcortree=916 /SigmaFactorBS="tacaaacgcctgaaaaaattcaacttgtccgctgaatcataa AGCATACttccttcaggaaatGGAAACGTTATGtattgaaggagggtgttacgatgaa t" /listShort="sspH" /GFF_Attribute="listLong" promotor_-10 885597..885608 /Source="Nicolas_upshift_promotors" /id="U621" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp="0.995004995004995" /psig="0.995004995004995" /xcortree=916 /SigmaFactorBS="tacaaacgcctgaaaaaattcaacttgtccgctgaatcataa AGCATACttccttcaggaaatGGAAACGTTATGtattgaaggagggtgttacgatgaa t" /listShort="sspH" /GFF_Attribute="listLong" /label="promotor_-10" CDS 885629..885808 /gene="sspH" /locus_tag="BSU_08110" /old_locus_tag="BSU08110" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:10333516" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10333516; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="small acid-soluble spore protein" /protein_id="NP_388692.1" /db_xref="EnsemblGenomes-Gn:BSU08110" /db_xref="EnsemblGenomes-Tr:CAB12640" /db_xref="GOA:O31552" /db_xref="InterPro:IPR012610" /db_xref="SubtiList:BG12917" /db_xref="UniProtKB/Swiss-Prot:O31552" /translation="MNIQRAKEIVESPDMKKVTYNGVPIYIQHVNEETGTARIYPLDE PQEEHEVQLNSLKED*" gene 885629..885808 /gene="sspH" /locus_tag="BSU_08110" /old_locus_tag="BSU08110" downshifts 885792 /Source="Nicolas_upshifts" /id="D407" /incds=0 /nref=96 /ntot=181 /MaxReadThrough="1.9176" /MaxDrop="6.06509" /score="5.08326573" /energy="-12" /TU="NA" /idTUdmin="U619" /TUdmin=0 /isTUend="TRUE" CDS complement(885844..886173) /gene="yfjF" /locus_tag="BSU_08120" /old_locus_tag="BSU08120" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative membrane protein" /protein_id="NP_388693.1" /db_xref="EnsemblGenomes-Gn:BSU08120" /db_xref="EnsemblGenomes-Tr:CAB12641" /db_xref="GOA:O31553" /db_xref="InterPro:IPR003844" /db_xref="SubtiList:BG12908" /db_xref="UniProtKB/Swiss-Prot:O31553" /translation="MMLITILLFLAAGLAEIGGGYLVWLWLREAKPAGYGIAGALILI VYGILPTFQSFPSFGRVYAAYGGVFIVLAVLWGWLVDRKTPDLYDWIGAFICLIGVCV ILFAPRG*" gene complement(885844..886173) /gene="yfjF" /locus_tag="BSU_08120" /old_locus_tag="BSU08120" downshifts complement(885858) /Source="Nicolas_upshifts" /id="D408" /incds=0 /nref=96 /ntot=245 /MaxReadThrough="2.05328" /MaxDrop="6.2642" /score="34.1179702" /energy="-15.8" /TU="NA" /idTUdmin="U623" /TUdmin="-12" /isTUend="TRUE" CDS complement(886223..886681) /gene="yfjE" /locus_tag="BSU_08130" /old_locus_tag="BSU08130" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative integral inner membrane protein" /protein_id="NP_388694.1" /db_xref="EnsemblGenomes-Gn:BSU08130" /db_xref="EnsemblGenomes-Tr:CAB12642" /db_xref="GOA:O31554" /db_xref="InterPro:IPR035324" /db_xref="SubtiList:BG12907" /db_xref="UniProtKB/Swiss-Prot:O31554" /translation="MSEALTFESKYALLYLGGGLLAMIYGLITFFMAFPAFTSRGNVI FTIKTGPSGEIFLRKRSVLFSEVKRLYMGRHQYSLKGIFFEDIIIEKTDGKIVRIPTW NIITNPLFFEAVERYILPHLNEEAQNNWISQFTEVQRKAYLKEFENHPKL*" gene complement(886223..886681) /gene="yfjE" /locus_tag="BSU_08130" /old_locus_tag="BSU08130" S_feature complement(886682..886774) /Source="Nicolas_S_feature" /locus_tag="new_886682_886774_c" /HighExp="BI, BC, S2, Sw, HiOs, HiTm, S5, ferm, S4, nit" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.992" /TUlongSig="NA" /TUlongPSig="NA" /label="S282" CDS complement(886775..887332) /gene="yfjD" /locus_tag="BSU_08140" /old_locus_tag="BSU08140" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative integral inner membrane protein" /protein_id="NP_388695.1" /db_xref="EnsemblGenomes-Gn:BSU08140" /db_xref="EnsemblGenomes-Tr:CAB12643" /db_xref="GOA:O31555" /db_xref="InterPro:IPR035324" /db_xref="SubtiList:BG12906" /db_xref="UniProtKB/Swiss-Prot:O31555" /translation="MKNQEIIEVKSKMFLRIWAFVGSAGMGLACLWLFYMGITFQTKY YLLAIPAGFLFTLFCLYLFIIFFPAFTPRGNTIFRIKTGKNGEVFTDKVSVTFTDIKK IEMSRHKFSLKGIFQEDILIQTVDQKTIRIPTWNIIPNPLFFEAVERYILPHLNEEAK SNWIGQFTDIQRSAYLKEFENHPKL*" gene complement(886775..887332) /gene="yfjD" /locus_tag="BSU_08140" /old_locus_tag="BSU08140" promotor_-35 887198..887203 /Source="Nicolas_upshift_promotors" /id="U622" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1171 /SigmaFactorBS="tataaacaaaacaaggtgaacagaaagccagcaggaatggct aatagGTAATAtttcgtttgaaacgTAATACCCATATAAAAGAGccacaaacatgcta a" /listShort="S283" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 887211 /Source="Nicolas_upshifts" /id="U622" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1171 /SigmaFactorBS="tataaacaaaacaaggtgaacagaaagccagcaggaatggct aatagGTAATAtttcgtttgaaacgTAATACCCATATAAAAGAGccacaaacatgcta a" /listShort="S283" /GFF_Attribute="listLong" promotor_-10 887218..887236 /Source="Nicolas_upshift_promotors" /id="U622" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1171 /SigmaFactorBS="tataaacaaaacaaggtgaacagaaagccagcaggaatggct aatagGTAATAtttcgtttgaaacgTAATACCCATATAAAAGAGccacaaacatgcta a" /listShort="S283" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 887222..887809 /Source="Nicolas_S_feature" /locus_tag="new_887222_887809" /HighExp="S4, S5, S6, S3, S8, S7, LoTm, T5.0H, T4.0H, Pyr" /AntisenseName="yfjC" /AntisenseCor="9.3643586039105595E-2" /AntisenseRegPval="-0.9" /CDS_PredictionProba="NA" /TUshortSig="SigEF" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S283" CDS complement(887364..888131) /gene="yfjC" /locus_tag="BSU_08150" /old_locus_tag="BSU08150" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 14563871" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_388696.1" /db_xref="EnsemblGenomes-Gn:BSU08150" /db_xref="EnsemblGenomes-Tr:CAB12644" /db_xref="SubtiList:BG12905" /db_xref="UniProtKB/Swiss-Prot:O31556" /translation="MKQFTISIEELLFCFYSEGFFEQGMALKQAYFPEIEDEQLGALF EAACRSLLAKDAAEYRNHQYRLKDEYCPFIHVLNDADYTVKLSKFNGQGAEQNVSCHV SKFGTYSHELLFDEQVHRITKMESSEGLLAKTDEFLHIIDTEDKRESIVTLTSNEFEK LLEGASDNPSYLKEFLEKHDHQEDVTRFANDLALRKGKMDTLMRLAYGKDNTPEVADM AFVLPGAHHTWLVTGITQNEFSILPAHKDVVNQIISK*" gene complement(887364..888131) /gene="yfjC" /locus_tag="BSU_08150" /old_locus_tag="BSU08150" CDS complement(888143..889366) /gene="yfjB" /locus_tag="BSU_08160" /old_locus_tag="BSU08160" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type s: structure" /codon_start=1 /transl_table=11 /product="putative phage protein" /protein_id="NP_388697.1" /db_xref="EnsemblGenomes-Gn:BSU08160" /db_xref="EnsemblGenomes-Tr:CAB12645" /db_xref="SubtiList:BG12904" /db_xref="UniProtKB/Swiss-Prot:O31557" /translation="MSGNIAVDPDKLEQLANDVVTELTDMENKYKDLHVELGQMILQC DPRYSSCFSGVGDAWSSGKALVTKLSDNEIFIRKTGDKFVEQDDILRKLYNAYDKYGT MTSLTALMLTQGKYYGLGLTKFVKQPSGLHTAQHSKLLLDISRAVDSSRYQKAARVLL NPKYLLKKTNRPFSDLVHKKFTKYFPQDTVDFSNSVRSYTKGFLNEAGVRSTLKDVGK TGLRFAKGNAITATLITGATETFGAGVKIAENYAKYQDKPEVLKRENAKAVGNAVNNT IFVAGGATAGAVIGGAIGSFAGPVGTVLLGAAGSYIGGVVGEQIAKYTAGFAEKAALK LKEPIHAVVDTAKKGLESAGKVVKSVNDGIDAANKSIHKGIDSAKKGMEKAKKTADSL IHGATHFLKGKFSFG*" gene complement(888143..889366) /gene="yfjB" /locus_tag="BSU_08160" /old_locus_tag="BSU08160" CDS complement(889372..889686) /gene="yfjA" /locus_tag="BSU_08170" /old_locus_tag="BSU08170" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_388698.1" /db_xref="EnsemblGenomes-Gn:BSU08170" /db_xref="EnsemblGenomes-Tr:CAB12646" /db_xref="InterPro:IPR010310" /db_xref="InterPro:IPR036689" /db_xref="SubtiList:BG12903" /db_xref="UniProtKB/Swiss-Prot:O31558" /translation="MDSYKVIELANKYSAAAEEVRSSKMLLESRLSALGDAWQGKARD SFDQDFEETKAAYDQFEQELLETSQELKAAAVKIEERKAEIARMEELERKAREERHKL GR*" gene complement(889372..889686) /gene="yfjA" /locus_tag="BSU_08170" /old_locus_tag="BSU08170" promotor_-10 complement(889734..889753) /Source="Nicolas_upshift_promotors" /id="U623" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.852147852147852" /psig="0.992007992007992" /xcortree=2761 /SigmaFactorBS="cgcccttccaattcttatgaaaaggttcttttgtacGATTcg gatacatgccgaATTATTTATAATCATTTATAtaaaacatccaattgtgcgtgaattt a" /listShort="yfjA, yfjB, yfjC, yfjD, S282, yfjE, yfjF" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(889747) /Source="Nicolas_upshifts" /id="U623" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.852147852147852" /psig="0.992007992007992" /xcortree=2761 /SigmaFactorBS="cgcccttccaattcttatgaaaaggttcttttgtacGATTcg gatacatgccgaATTATTTATAATCATTTATAtaaaacatccaattgtgcgtgaattt a" /listShort="yfjA, yfjB, yfjC, yfjD, S282, yfjE, yfjF" /GFF_Attribute="listLong" promotor_-35 complement(889768..889771) /Source="Nicolas_upshift_promotors" /id="U623" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.852147852147852" /psig="0.992007992007992" /xcortree=2761 /SigmaFactorBS="cgcccttccaattcttatgaaaaggttcttttgtacGATTcg gatacatgccgaATTATTTATAATCATTTATAtaaaacatccaattgtgcgtgaattt a" /listShort="yfjA, yfjB, yfjC, yfjD, S282, yfjE, yfjF" /GFF_Attribute="listLong" /label="promotor_-35" misc_feature 889978..889997 /Source="Nicolas_upshift_promotors" /id="U624" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.258741258741259" /psig="0.684315684315684" /xcortree=342 /SigmaFactorBS="cactaaagttgatcaaatgacctaagtgcgccaaacgtgtta cgggacgagctatctCATGGTATAAATGGAATTGTaaacgttatcaaggaggtcgtca t" /listShort="malA, malR, malP, malQ" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 889981 /Source="Nicolas_upshifts" /id="U624" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.258741258741259" /psig="0.684315684315684" /xcortree=342 /SigmaFactorBS="cactaaagttgatcaaatgacctaagtgcgccaaacgtgtta cgggacgagctatctCATGGTATAAATGGAATTGTaaacgttatcaaggaggtcgtca t" /listShort="malA, malR, malP, malQ" /GFF_Attribute="listLong" CDS 890022..891371 /gene="malA" /locus_tag="BSU_08180" /old_locus_tag="BSU08180" /EC_number="3.2.1.122" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:9765262, 10329789, 11489864, 15341727, 15670594, 16707683, 17676871, 20698522" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9765262, 10329789, 11489864, 15341727, 15670594, 16707683, 17676871, 20698522; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="6-phospho-alpha-glucosidase" /protein_id="NP_388699.1" /db_xref="EnsemblGenomes-Gn:BSU08180" /db_xref="EnsemblGenomes-Tr:CAB12647" /db_xref="GOA:P54716" /db_xref="InterPro:IPR001088" /db_xref="InterPro:IPR015955" /db_xref="InterPro:IPR019802" /db_xref="InterPro:IPR022616" /db_xref="InterPro:IPR036291" /db_xref="PDB:1U8X" /db_xref="SubtiList:BG11839" /db_xref="UniProtKB/Swiss-Prot:P54716" /translation="MKKKSFSIVIAGGGSTFTPGIVLMLLDHLEEFPIRKLKLYDNDK ERQDRIAGACDVFIREKAPDIEFAATTDPEEAFTDVDFVMAHIRVGKYAMRALDEQIP LKYGVVGQETCGPGGIAYGMRSIGGVLEILDYMEKYSPDAWMLNYSNPAAIVAEATRR LRPNSKILNICDMPVGIEDRMAQILGLSSRKEMKVRYYGLNHFGWWTSIQDQEGNDLM PKLKEHVSQYGYIPKTEAEAVEASWNDTFAKARDVQAADPDTLPNTYLQYYLFPDDMV KKSNPNHTRANEVMEGREAFIFSQCDMITREQSSENSEIKIDDHASYIVDLARAIAYN TGERMLLIVENNGAIANFDPTAMVEVPCIVGSNGPEPITVGTIPQFQKGLMEQQVSVE KLTVEAWAEKSFQKLWQALILSKTVPNARVARLILEDLVEANKDFWPELDQSPTRIS* " gene 890022..891371 /gene="malA" /locus_tag="BSU_08180" /old_locus_tag="BSU08180" misc_feature 891400..891419 /Source="Nicolas_upshift_promotors" /id="U625" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.97902097902098" /psig=1 /xcortree=3083 /SigmaFactorBS="cttgatcaaagcccaacccgcatatcataaatgaaattcccc cattttcgaatctgtaATTGTATATAATAGAAAGAAaatggggggatctgatatgcag c" /listShort="malR, malP" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 891402 /Source="Nicolas_upshifts" /id="U625" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.97902097902098" /psig=1 /xcortree=3083 /SigmaFactorBS="cttgatcaaagcccaacccgcatatcataaatgaaattcccc cattttcgaatctgtaATTGTATATAATAGAAAGAAaatggggggatctgatatgcag c" /listShort="malR, malP" /GFF_Attribute="listLong" CDS 891436..892200 /gene="malR" /locus_tag="BSU_08190" /old_locus_tag="BSU08190" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:11489864, 16707683, 22720735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11489864, 16707683, 22720735; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional activator of the Mal operon" /protein_id="NP_388700.1" /db_xref="EnsemblGenomes-Gn:BSU08190" /db_xref="EnsemblGenomes-Tr:CAB12648" /db_xref="GOA:P54717" /db_xref="InterPro:IPR000281" /db_xref="InterPro:IPR001347" /db_xref="InterPro:IPR009057" /db_xref="InterPro:IPR035472" /db_xref="InterPro:IPR036388" /db_xref="SubtiList:BG11847" /db_xref="UniProtKB/Swiss-Prot:P54717" /translation="MQLEELINQHYSKLNDNDFHILKYILNHKHTCYHLGIDALAKAC SVSRSSILRLAQKLGFSGYSEFRVFLKWEDQPEEGESMSFEKLLDDIEANLKFLRTKD MTDMCQLIDAADRIFVYGSGNAQKICARDLQRMFIPRHRYLILIEDTNEFNLMRDDFK VNDLFIIISLSGETPELIPQARMLSAKGIPFISITNLKNNVLAQLTPHNLYATSKPVT LSDRTEIVAFAPFFLVGEALFRAYVDYKEAEKNDNE*" gene 891436..892200 /gene="malR" /locus_tag="BSU_08190" /old_locus_tag="BSU08190" promotor_-10 complement(891580..891594) /Source="Nicolas_upshift_promotors" /id="U626" /multdbtbs="-" /comp="M9" /sig="Sig-" /pcomp="0.454545454545455" /psig="0.454545454545455" /xcortree=655 /SigmaFactorBS="cttcttccggctgatcttcccactttaaaaagacgcgaaatt cactgtaaccgcTGAAACCgagcttttgggcaagCCGTAAAATTGAGGAacgcgatac a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 complement(891610..891616) /Source="Nicolas_upshift_promotors" /id="U626" /multdbtbs="-" /comp="M9" /sig="Sig-" /pcomp="0.454545454545455" /psig="0.454545454545455" /xcortree=655 /SigmaFactorBS="cttcttccggctgatcttcccactttaaaaagacgcgaaatt cactgtaaccgcTGAAACCgagcttttgggcaagCCGTAAAATTGAGGAacgcgatac a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" upshifts complement(891610) /Source="Nicolas_upshifts" /id="U626" /multdbtbs="-" /comp="M9" /sig="Sig-" /pcomp="0.454545454545455" /psig="0.454545454545455" /xcortree=655 /SigmaFactorBS="cttcttccggctgatcttcccactttaaaaagacgcgaaatt cactgtaaccgcTGAAACCgagcttttgggcaagCCGTAAAATTGAGGAacgcgatac a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" CDS 892215..893798 /gene="malP" /locus_tag="BSU_08200" /old_locus_tag="BSU08200" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:15849754, 16707683, 16850406, 22720735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15849754, 16707683, 16850406, 22720735; Product type t: transporter" /codon_start=1 /transl_table=11 /product="phosphotransferase system (PTS) maltose-specificenzyme IICB component" /protein_id="NP_388701.1" /db_xref="EnsemblGenomes-Gn:BSU08200" /db_xref="EnsemblGenomes-Tr:CAB12649" /db_xref="GOA:P54715" /db_xref="InterPro:IPR001996" /db_xref="InterPro:IPR003352" /db_xref="InterPro:IPR004719" /db_xref="InterPro:IPR010975" /db_xref="InterPro:IPR013013" /db_xref="InterPro:IPR018113" /db_xref="InterPro:IPR036878" /db_xref="SubtiList:BG11848" /db_xref="UniProtKB/Swiss-Prot:P54715" /translation="MMQKIQRFGSAMFVPVLLFAFAGIIVGISTLFKNKTLMGPLADP DGFWYQCWYIIEQGGWTVFNQMPLLFAIGIPVALAKKAQARACLEALTVYLTFNYFVS AILTVWGGAFGVDMNQEVGGTSGLTMIAGIKTLDTNIIGAIFISSIVVFLHNRYFDKK LPDFLGIFQGSTYIVMISFFIMIPIALAVSYIWPMVQSGIGSLQSFLVASGAVGVWIY TFLERILIPTGLHHFIYTPFIYGPAVAEGGIVTYWAQHLGEYSQSAKPLKELFPQGGF ALHGNSKIFGIPGIALAFYVTAKKEKKKLVAGLLIPVTLTAIVAGITEPIEFTFLFIS PFLFAVHAVLAATMSTVMYMAGVVGNMGGGLIEAVTLNWIPLFGSHGMTYVYQILIGL SFTAIYFFVFRFLILKFNIATPGREKDEQQETKLYSKKEYRERKNKDETASAAETADD TAFLYIEALGGKDNITEVTNCATRLRVSVKDETKVEPDSVFRALGAHGVVRNGKAFQV IIGLSVPQMRERVEKILNQ*" gene 892215..893798 /gene="malP" /locus_tag="BSU_08200" /old_locus_tag="BSU08200" downshifts 893778 /Source="Nicolas_upshifts" /id="D409" /incds=0 /nref=23 /ntot=46 /MaxReadThrough="3.26652" /MaxDrop="4.69656" /score="8.65399085" /energy="-10.9" /TU="U624" /idTUdmin="U625" /TUdmin=836 /isTUend="FALSE" promotor_-35 893827..893834 /Source="Nicolas_upshift_promotors" /id="U627" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.986013986013986" /psig=1 /xcortree=2032 /SigmaFactorBS="aaagactgccctccttttcgggagggttttCGTTTGCCgtca aaaagaccgcCATAGTAAAGTAAAGAAAGAgacaatcgagtaaaaaggggtttggagg c" /listShort="malQ, yfiC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 893849..893868 /Source="Nicolas_upshift_promotors" /id="U627" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.986013986013986" /psig=1 /xcortree=2032 /SigmaFactorBS="aaagactgccctccttttcgggagggttttCGTTTGCCgtca aaaagaccgcCATAGTAAAGTAAAGAAAGAgacaatcgagtaaaaaggggtttggagg c" /listShort="malQ, yfiC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 893857 /Source="Nicolas_upshifts" /id="U627" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.986013986013986" /psig=1 /xcortree=2032 /SigmaFactorBS="aaagactgccctccttttcgggagggttttCGTTTGCCgtca aaaagaccgcCATAGTAAAGTAAAGAAAGAgacaatcgagtaaaaaggggtttggagg c" /listShort="malQ, yfiC" /GFF_Attribute="listLong" CDS 893904..895625 /gene="yfiB" /locus_tag="BSU_08210" /old_locus_tag="BSU08210" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 16707683; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative xenobiotic ABC transporter subunit (ATP-binding protein)" /protein_id="NP_388702.1" /db_xref="EnsemblGenomes-Gn:BSU08210" /db_xref="EnsemblGenomes-Tr:CAB12650" /db_xref="GOA:P54718" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR011527" /db_xref="InterPro:IPR017871" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR036640" /db_xref="SubtiList:BG11849" /db_xref="UniProtKB/Swiss-Prot:P54718" /translation="MQKALSFLKPYSLLAGIALILMLTELAVELMQPLLIAKIIDDGI LKQDLRHVWIWGTVMIGLTVLSFAAGMLNSFYAAHVSQSFSYDTRKGLFQKIQSFSYS TFGQFSSSSYITRLTNDVTQVQNMIFMSLRFMLRAPLMIAGGIVLSLAVNVKLGFFLL VTIPILILFLLWVLRKGGALFRSVQKRLDQVNTIMQENLIAIKLIKALLRGSHEVKRF IKANTRLMEKTVSAFQLVEFTMPVLMLLMNLCILLILWAGSYSITSGSTQVGDVVAII NYATRITGALSMFPFLIMIFTRAKASGDRIGEVLETEGDEREEGTISDRLSGRIEFQH VSFRYPEMDREALRNVSFSAKPRETIAILGATGSGKSTLFQLIPRLYQPDSGRIYIDE KPVQDIPAEGLRRQIGYVPQEVLLFSGTIKENIAWGKENASLDEIMDAAKLAQIHETI LKLPNGYDTVLGQRGVNLSGGQKQRISIARALIRKPAILLLDDSTSALDLQTEAKLLE AISTYHCTTLIITQKITTAMKADQILLLEDGELIEKGTHSELLSESQLYKRIYESQFG REGSESC*" gene 893904..895625 /gene="yfiB" /locus_tag="BSU_08210" /old_locus_tag="BSU08210" CDS 895619..897433 /gene="yfiC" /locus_tag="BSU_08220" /old_locus_tag="BSU08220" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative ABC transporter (ATP-binding protein)" /protein_id="NP_388703.1" /db_xref="EnsemblGenomes-Gn:BSU08220" /db_xref="EnsemblGenomes-Tr:CAB12651" /db_xref="GOA:P54719" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR011527" /db_xref="InterPro:IPR017871" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR036640" /db_xref="SubtiList:BG11850" /db_xref="UniProtKB/Swiss-Prot:P54719" /translation="MLKDIRKPFQYPKLPIDKKEGAKKRAKAKDTKGTLRRIWSYLAE RKGLLILVMLMVVISAIFGLLGPFVIGKAIDHFIVGKTVSGLIPVLLLLLAIYIIQSL SLWFQNYWMITISQGTVFRMRSELFTHLHELPIPFFDKQRHGELMSRVTNDIENVSST LNTSVIQILSSVITFVGTIAVMLYMSPLLTLITLTIIPVMAASLKWITNRTGKLFKEQ QKNLGDLNGYIEESVSGAKVIKAYSREKQITAEFLEKNAALKTSGFWAQTISGFIPKV MNSLNNLSFTMIAAIGGLFALKGWISIGSIVVFAEYSRQFTRPLNDLANQFNTMLSAI AGAERVFDVLDEKEEREDEKNAVHQPIQTGSIEFRDVSFGYDKGQQTLKHLQFTVPAG QSIAFVGPTGAGKTTVTNLLARFYEPNDGKILIDGTDIKTLTRASLRKNMGFVLQDSF LFQGTIRENIRYGRLDASDQEVEAAAKTANAHSFIERLPKGYDTVLTQNGSGISQGQK QLISIARAVLADPVLLILDEATSNIDTVTEVNIQEALARLMEGRTSVIIAHRLNTIQR ADQIVVLKNGEMIEKGSHDELIRQKGFYSDLYESQFEK*" gene 895619..897433 /gene="yfiC" /locus_tag="BSU_08220" /old_locus_tag="BSU08220" downshifts 897408 /Source="Nicolas_upshifts" /id="D410" /incds=0 /nref=103 /ntot=190 /MaxReadThrough="2.4559" /MaxDrop="5.61906" /score="24.4395842" /energy="-11" /TU="NA" /idTUdmin="U627" /TUdmin=0 /isTUend="TRUE" promotor_-35 897515..897522 /Source="Nicolas_upshift_promotors" /id="U628" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.75024975024975" /psig=1 /xcortree=1845 /SigmaFactorBS="cttttatttcattttcgtaaaatgtaacaaaattaCTTGACG TaaacaagttatgtATATATACTAGCTTACATTAagtaagtgataacatttatcaagg a" /listShort="catD, catE" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 897536..897555 /Source="Nicolas_upshift_promotors" /id="U628" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.75024975024975" /psig=1 /xcortree=1845 /SigmaFactorBS="cttttatttcattttcgtaaaatgtaacaaaattaCTTGACG TaaacaagttatgtATATATACTAGCTTACATTAagtaagtgataacatttatcaagg a" /listShort="catD, catE" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 897540 /Source="Nicolas_upshifts" /id="U628" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.75024975024975" /psig=1 /xcortree=1845 /SigmaFactorBS="cttttatttcattttcgtaaaatgtaacaaaattaCTTGACG TaaacaagttatgtATATATACTAGCTTACATTAagtaagtgataacatttatcaagg a" /listShort="catD, catE" /GFF_Attribute="listLong" CDS 897588..897992 /gene="catD" /locus_tag="BSU_08230" /old_locus_tag="BSU08230" /EC_number="1.13.11.2" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:15849754, 16872404, 16850406, 17407181, 20639328" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15849754, 16872404, 16850406, 17407181, 20639328; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="catechol-2,3-dioxygenase membrane subunit" /protein_id="NP_388704.1" /db_xref="EnsemblGenomes-Gn:BSU08230" /db_xref="EnsemblGenomes-Tr:CAB12652" /db_xref="GOA:P54720" /db_xref="InterPro:IPR032808" /db_xref="SubtiList:BG11851" /db_xref="UniProtKB/Swiss-Prot:P54720" /translation="MNKSFEIGTLLLRVITGIIFFVHGLSKFQGMEGTIQFFGSIGLP SFMAYVIAAIELIGGVLVFFGLATRIVGVLFALTLIGAIITVKLKAPFMGNAEFDYLL LLTSIHLALTGSRFLALDPFVFKGKKNGNVSA*" gene 897588..897992 /gene="catD" /locus_tag="BSU_08230" /old_locus_tag="BSU08230" CDS 898010..898867 /gene="catE" /locus_tag="BSU_08240" /old_locus_tag="BSU08240" /EC_number="1.13.11.2" /function="16.11: Scavenge (Catabolism)" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:17407181, 16872404" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 17407181, 16872404; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="catechol-2,3-dioxygenase subunit" /protein_id="NP_388705.2" /db_xref="EnsemblGenomes-Gn:BSU08240" /db_xref="EnsemblGenomes-Tr:CAB12653" /db_xref="GOA:P54721" /db_xref="InterPro:IPR000486" /db_xref="InterPro:IPR004360" /db_xref="InterPro:IPR029068" /db_xref="SubtiList:BG11852" /db_xref="UniProtKB/Swiss-Prot:P54721" /translation="MTSIHEDTHIGYAKLTIRSLERSLQFYCNVIGFQVLKKTDRQAE LTADGKRVLLILEENPSAVVLPERSVTGLYHFAILLPDRKELGIALARLIEHGIAIGH GDHAVSEALYLSDPDGNGIEMYADRPRSTWQRDREGNYVMTTTAVDIEGLLEEAGDER KTSLPNDTIIGHIHLHVSDLKEAKAFYTDVLGFDIVGNYAGMSALFVSAGGYHHHIGL NIWAGRNAPPKPTNASGLDYYTVVLPHQEELDLVANRVKHAGYSIEETENSFRVKDPV SGAYITFVI*" gene 898010..898867 /gene="catE" /locus_tag="BSU_08240" /old_locus_tag="BSU08240" downshifts 898854 /Source="Nicolas_upshifts" /id="D411" /incds=0 /nref=4 /ntot=21 /MaxReadThrough="0.66359" /MaxDrop="3.74886" /score="50.8573531" /energy="-19.7" /TU="NA" /idTUdmin="U628" /TUdmin=16 /isTUend="TRUE" CDS 898961..899905 /gene="yfiF" /locus_tag="BSU_08250" /old_locus_tag="BSU08250" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 10704478; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative transcriptional regulator (AraC/XylS family; cupin family)" /protein_id="NP_388706.1" /db_xref="EnsemblGenomes-Gn:BSU08250" /db_xref="EnsemblGenomes-Tr:CAB12654" /db_xref="GOA:P54722" /db_xref="InterPro:IPR003313" /db_xref="InterPro:IPR009057" /db_xref="InterPro:IPR018060" /db_xref="InterPro:IPR018062" /db_xref="SubtiList:BG11853" /db_xref="UniProtKB/Swiss-Prot:P54722" /translation="MELNHLVTGKIALNQYVHRLEQKDVSFYVHYWGAMTNHYNTLLH KHSFYEICYVVRGEGYYLEGDRTYPLREQTIFLSKPEHLHQIKSETGLFLFYVAFELS EDQSSAEWIKVMEEVKQSPFITMQLKDGEPPGLLWKTLMLQAAQPVNAFDKEILSHLS HALILSLIQTFLPYAQRPKQKQPIHTSSALLTEVKLHIKDNLSQPLKLTDVASHFHIS GRHLSRLFAAELGVSYSEFVQNEKINKAAELLKSTNLSIKEIAEEIGFSVHYFTRVFS AKIGSSPGLFRSLYKDSKMTAFQINKPFQKIEQAKPHE*" gene 898961..899905 /gene="yfiF" /locus_tag="BSU_08250" /old_locus_tag="BSU08250" downshifts complement(899772) /Source="Nicolas_upshifts" /id="D412" /incds=1 /nref=1 /ntot=2 /MaxReadThrough="-0.20031" /MaxDrop="3.51831" /score="-4.19869956" /energy="-9.5" /TU="NA" /idTUdmin="U632" /TUdmin=9372 /isTUend="FALSE" promotor_no_box complement(899820..899920) /Source="Nicolas_upshift_promotors" /id="U629" /multdbtbs="-" /comp="M21" /sig="Sig-" /pcomp="0.533466533466533" /psig="0.034965034965035" /xcortree=1481 /SigmaFactorBS="tcatttcaggacatcttattcgtgcggcttggcctgttcgat tttttgaaaaggtttattgatttgaaatgcggtcatttttgagtctttataaagggag c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_no_box" upshifts complement(899860) /Source="Nicolas_upshifts" /id="U629" /multdbtbs="-" /comp="M21" /sig="Sig-" /pcomp="0.533466533466533" /psig="0.034965034965035" /xcortree=1481 /SigmaFactorBS="tcatttcaggacatcttattcgtgcggcttggcctgttcgat tttttgaaaaggtttattgatttgaaatgcggtcatttttgagtctttataaagggag c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" CDS 900080..901528 /gene="yfiG" /locus_tag="BSU_08260" /old_locus_tag="BSU08260" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative sugar/proton transporter" /protein_id="NP_388707.1" /db_xref="EnsemblGenomes-Gn:BSU08260" /db_xref="EnsemblGenomes-Tr:CAB12655" /db_xref="GOA:P54723" /db_xref="InterPro:IPR003663" /db_xref="InterPro:IPR005828" /db_xref="InterPro:IPR005829" /db_xref="InterPro:IPR020846" /db_xref="InterPro:IPR036259" /db_xref="SubtiList:BG11854" /db_xref="UniProtKB/Swiss-Prot:P54723" /translation="MSTKKKEAVIGKESLAHKGLLRTITLVSTFGGLLFGYDTGVING ALPFMATAGQLNLTPVTEGLVASSLLLGAAFGAMFGGRLSDRHGRRKTILYLALLFIA ATLGCTFSPNASVMIAFRFLLGLAVGCASVTVPTFLAEISPAERRGRIVTQNELMIVI GQLLAYTFNAIIGSTMGESANVWRYMLVIATLPAVVLWFGMLIVPESPRWLAAKGRMG DALRVLRQIREDSQAQQEIKEIKHAIEGTAKKAGFHDFQEPWIRRILFIGIGIAIVQQ ITGVNSIMYYGTEILREAGFQTEAALIGNIANGVISVIAVIFGIWLLGKVRRRPMLII GQIGTMTALLLIGILSIVLEGTPALPYVVLSLTILFLAFQQTAISTVTWLMLSEIFPM HVRGLGMGISTFCLWTANFLIGFTFPILLNHIGMSATFFIFVAMNILAILFVKKYVPE TKGRSLEQLEHSFRQYGRRADQEIQNQTTHLS*" gene 900080..901528 /gene="yfiG" /locus_tag="BSU_08260" /old_locus_tag="BSU08260" CDS 901555..902496 /gene="yfiH" /locus_tag="BSU_08270" /old_locus_tag="BSU08270" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative sugar-phosphate epimerase/isomerase" /protein_id="NP_388708.1" /db_xref="EnsemblGenomes-Gn:BSU08270" /db_xref="EnsemblGenomes-Tr:CAB12656" /db_xref="InterPro:IPR011418" /db_xref="InterPro:IPR013022" /db_xref="InterPro:IPR036237" /db_xref="SubtiList:BG11855" /db_xref="UniProtKB/Swiss-Prot:P54724" /translation="MKLSYVTDSLGHLPFEDMLNFAAKLGIDTLEMTTGGWSPAPHLN LDELLQSSEKRKEFSQALEKRNMTLCALNCSGNPLDPGELGKSHRDITDKTMELAGLL GVKKVIMMSGLPAGGPDDKVPNWITYTVSWPPVLKDILNYQWEDVAIPYWKKLVKKAE ACGVGKIALENFSSQLVYNPETLFRLRNAVGPMVGLNLDPSHLLWMGADPIIAARELG SAIHHVHGKDVRIERYLSAVNGLLETKEVTDPANRAWNYVAVGCGQDLQWWKEFFSVV KMMGYEGEVSLEMEDLTMSPEAGIRTSVEALKQTISQ*" gene 901555..902496 /gene="yfiH" /locus_tag="BSU_08270" /old_locus_tag="BSU08270" CDS 902506..903687 /gene="yfiI" /locus_tag="BSU_08280" /old_locus_tag="BSU08280" /EC_number="1.-.-.-" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 26438878; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative oxidoreductase" /protein_id="NP_388709.1" /db_xref="EnsemblGenomes-Gn:BSU08280" /db_xref="EnsemblGenomes-Tr:CAB12657" /db_xref="GOA:P94437" /db_xref="InterPro:IPR000683" /db_xref="InterPro:IPR004104" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG12214" /db_xref="UniProtKB/Swiss-Prot:P94437" /translation="MMLNGERIISKPLRWAMVGGGRLSQVGYKHRIGALRDNTAFQLT AGAFDIDAERGKDFGVNLGVDAERCYPNYQTMFAEEAKRQDGIEVVSIATPNGTHYEI CKAALEAGVHVICEKPLFFTSAEGQEIKALAEKKGKIVGVTYGFSGNQMLLQMRAMIE QGMIGDIRVVDLQYTHGFCATDEGEKISAAQKWRVDPAIAGPSFVLGDLSTHTYYMSQ LIMPKMKIKELLCDRQSFVGSRAPLEDNAHVLMHYENGAVGTMWTSSINAGCMDGHRI RIVGSKASIEWWDSKPNELTYEVQGEPGQTLVRGMPYLDDVCNADERLGALHSEGLSE AWANIYLKFAIAIDAKNREDEEILNNLVYPDIDAGIEGIRWIENCVRSANQGSVWVEF K*" gene 902506..903687 /gene="yfiI" /locus_tag="BSU_08280" /old_locus_tag="BSU08280" downshifts 903677 /Source="Nicolas_upshifts" /id="D413" /incds=0 /nref=40 /ntot=113 /MaxReadThrough="0.88387" /MaxDrop="5.80704" /score="14.819468" /energy="-13" /TU="NA" /idTUdmin="U630" /TUdmin="-2003" /isTUend="FALSE" promotor_-35 903747..903753 /Source="Nicolas_upshift_promotors" /id="U630" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.517482517482518" /psig="0.918081918081918" /xcortree=2137 /SigmaFactorBS="cggtttttattttccagaaacTCCTGTCaaaaatgccctgag GCAGGTATGATAAGAAGGGAattgggtatcgggagtgatgagcgtgaaagctcttttt t" /listShort="yfiJ, yfiK" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 903768..903787 /Source="Nicolas_upshift_promotors" /id="U630" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.517482517482518" /psig="0.918081918081918" /xcortree=2137 /SigmaFactorBS="cggtttttattttccagaaacTCCTGTCaaaaatgccctgag GCAGGTATGATAAGAAGGGAattgggtatcgggagtgatgagcgtgaaagctcttttt t" /listShort="yfiJ, yfiK" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 903786 /Source="Nicolas_upshifts" /id="U630" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.517482517482518" /psig="0.918081918081918" /xcortree=2137 /SigmaFactorBS="cggtttttattttccagaaacTCCTGTCaaaaatgccctgag GCAGGTATGATAAGAAGGGAattgggtatcgggagtgatgagcgtgaaagctcttttt t" /listShort="yfiJ, yfiK" /GFF_Attribute="listLong" CDS 903811..905013 /gene="linJ" /locus_tag="BSU_08290" /old_locus_tag="BSU08290" /function="16.12: Sense" /function="16.3: Control" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:11717295, 12618459, 28461449" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11717295, 12618459, 28461449; Product type rc: receptor" /codon_start=1 /transl_table=11 /product="two-component sensor histidine kinase [LinK] (linearmycin resistance, biofilm formation)" /protein_id="NP_388710.1" /db_xref="EnsemblGenomes-Gn:BSU08290" /db_xref="EnsemblGenomes-Tr:CAB12658" /db_xref="GOA:P94438" /db_xref="InterPro:IPR003594" /db_xref="InterPro:IPR011712" /db_xref="InterPro:IPR036890" /db_xref="SubtiList:BG12215" /db_xref="UniProtKB/Swiss-Prot:P94438" /translation="MKALFFTRMFTLMVSCLMYLSIVKEDNWFGYVFIAAGAAMYAAN HVLLTKETNAIWFCLIDIAIGFSFGFIFPGTGLFIIMLCPVAVAFFLRGFPKRTAWSV LCLSSILFLTVLIRTYAMFGNEFVIDHLTSMTFVVFCGVVGKLIRKLLDAQDTAKQQF QELTESHLALSAAHQELHLYAKQVEELTAIYERNRMAREIHDTVGHKMTALLVQLQLL REWQKRDSQKADETVGVCETLAREALDDVRLSVRTLQTENDPSLIESLKQLTEDFCKN AGVTTEFAVSGDPAIIPLSLHPTLIRTVQEALTNAKRHGGAAACSIQLACTTDSISLV IKDDGKGNPEAALGFGLLNMKKRAAEHGGMIRFESERDQGFTVNAEFSLANKKWSFGP VQQKESLS*" gene 903811..905013 /gene="linJ" /locus_tag="BSU_08290" /old_locus_tag="BSU08290" CDS 905010..905672 /gene="linK" /locus_tag="BSU_08300" /old_locus_tag="BSU08300" /function="16.5: Explore" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:11717295, 12618459, 28461449" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11717295, 12618459, 28461449; Product type r: regulator" /codon_start=1 /transl_table=11 /product="two-component response regulator [LinJ] (linearmycin resistance, biofilm formation)" /protein_id="NP_388711.1" /db_xref="EnsemblGenomes-Gn:BSU08300" /db_xref="EnsemblGenomes-Tr:CAB12659" /db_xref="GOA:P94439" /db_xref="InterPro:IPR000792" /db_xref="InterPro:IPR001789" /db_xref="InterPro:IPR011006" /db_xref="InterPro:IPR016032" /db_xref="InterPro:IPR036388" /db_xref="SubtiList:BG12216" /db_xref="UniProtKB/Swiss-Prot:P94439" /translation="MIKIIITDDQDIVREGLASLLQLREELDVIATARNGQEAFEKAK ELEPDIVLMDIRMPVSNGVEGTKLITSSLPSVKVLMLTTFKDSALIAEALEEGASGYL LKDMSADTIVKAVMTVHSGGMVLPPELTAQMLNEWKREKQLKGINEIEKPNELLDLTE REIEVLAELGYGLNNKEIAEKLYITEGTVKNHVSNIISKLAVRDRTQAAIYSVRYGVS VF*" gene 905010..905672 /gene="linK" /locus_tag="BSU_08300" /old_locus_tag="BSU08300" downshifts 905680 /Source="Nicolas_upshifts" /id="D414" /incds=0 /nref=114 /ntot=229 /MaxReadThrough="-0.0105699999999995" /MaxDrop="4.23231" /score="20.4785449" /energy="-7.6" /TU="NA" /idTUdmin="U630" /TUdmin=0 /isTUend="TRUE" CDS 905816..906751 /gene="bifL" /locus_tag="BSU_08310" /old_locus_tag="BSU08310" /function="16.8: Protect" /function="16.13: Shape" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:28461449" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 28461449; Product type t: transporter" /codon_start=1 /transl_table=11 /product="ABC transporter (ATP-binding protein) biofilm formation" /protein_id="NP_388712.2" /db_xref="EnsemblGenomes-Gn:BSU08310" /db_xref="EnsemblGenomes-Tr:CAB12660" /db_xref="GOA:P94440" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR017871" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG12217" /db_xref="UniProtKB/Swiss-Prot:P94440" /translation="MLQAENIKKAYGKKTIVKGISFSLKKGESFGLLGPNGAGKSTTI SMISGLVPHDSGNITVGGYVIGKETAKAKQKIGIVPQEIALYPTLTAHENLMFWGKMY GLTHGEAKKRAAEVLEYVGLTERAKDKIETFSGGMKRRINIGAALMHKPELLIMDEPT VGIDPQSRNHILETVKQLNETGMTVIYTSHYMEEVEFLCDRIGIIDQGEMIAIGTKTD LCSRLGGDTIIQLTVSGINEAFLVAIRSLAHVNDVTVHELELKIDISAAHHEKVVTSL LAEATAHHINLLSLQVQEPNLERLFLNLTGRTLRD*" gene 905816..906751 /gene="bifL" /locus_tag="BSU_08310" /old_locus_tag="BSU08310" CDS 906764..907954 /gene="bifM" /locus_tag="BSU_08320" /old_locus_tag="BSU08320" /function="16.8: Protect" /function="16.13: Shape" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:15849754, 16850406, 28461449" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15849754, 16850406, 28461449; Product type t: transporter" /codon_start=1 /transl_table=11 /product="ABC transporter (permease) biofilm formation" /protein_id="NP_388713.1" /db_xref="EnsemblGenomes-Gn:BSU08320" /db_xref="EnsemblGenomes-Tr:CAB12661" /db_xref="GOA:P94441" /db_xref="InterPro:IPR000412" /db_xref="SubtiList:BG12218" /db_xref="UniProtKB/Swiss-Prot:P94441" /translation="MKKSIWIAWKDVKIRITDRKGFMMLILMPLILTCILGAALGSVV DGGSRIDDIKVGYIQSDQSDTANMFTKDVLKKMKSIKVTKVGSKDKMKKLIDEKKIDV GIVIPNHWEAGKTSAVVNAAPDQTLKSSIIETAASSFIEQYKAVKEAASGSMDYISKT EAVKQGKLDPAQFAEKLAKTLEKETGDKLTIAEKSVGSKAVTSFQYYSAAMLCMFMLF HITVGAKSFLQEKDTETLARMLMTPAQKSVILFGKWLGTYLFAIIQFFIFLIVTINVF GVDWGGNLLLVSVLGLSYAAAVSGISMLLASCISDMKTADAIGGFGIQLLAVLGGSML PLYQFPDVLQSVSKAVPNRWALDGFLSLMEGGGWADLQKPVLLFAAIGFCSLVIGIRR LHTR*" gene 906764..907954 /gene="bifM" /locus_tag="BSU_08320" /old_locus_tag="BSU08320" CDS 907968..909125 /gene="bifN" /locus_tag="BSU_08330" /old_locus_tag="BSU08330" /function="16.8: Protect" /function="16.13: Shape" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:15849754, 16850406, 28461449" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15849754, 16850406, 28461449; Product type t: transporter" /codon_start=1 /transl_table=11 /product="ABC transporter (permease) biofilm formation" /protein_id="NP_388714.1" /db_xref="EnsemblGenomes-Gn:BSU08330" /db_xref="EnsemblGenomes-Tr:CAB12662" /db_xref="GOA:P94442" /db_xref="InterPro:IPR000412" /db_xref="SubtiList:BG12219" /db_xref="UniProtKB/Swiss-Prot:P94442" /translation="MKKILAICGIELSLIFKKPQNYLIMFAAPLLLTFVFGSMLSGND DKVRLAIVDQDDTILSQHYIRQLKAHDDMYVFENMSESKASEKLKQKKIAGIIVISRS FQTQLEKGKHPELIFRHGPELSEAPMVKQYAESALATLNIQVTAAKTASQTAGENWKA AYKTVFAKKHEDIVPAVTRQTLSDKKEGAEASDTASRAAGFSILFVMLTMMGAAGTIL EARKNGVWSRLLTASVSRAEIGAGYVLSFFVIGWIQFGILLLSTHWLFGINWGNPAAV IVLVSLFLLTVVGIGLMIAANVRTPEQQLAFGNLFVIATCMVSGMYWPIDIEPKFMQS IAEFLPQKWAMSGLTEIIANGARVTDILGICGILLAFAAITFAAGLKALRA*" gene 907968..909125 /gene="bifN" /locus_tag="BSU_08330" /old_locus_tag="BSU08330" promotor_-35 908079..908084 /Source="Nicolas_upshift_promotors" /id="U631" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.693306693306693" /psig="0.693306693306693" /xcortree=1182 /SigmaFactorBS="atgtttgctgccccgcttttgcttacctttgtatttgggAGT ATGctcagcggcaatgaTGATAAGGTGCGGCTTGCAatcgttgatcaggacgatacga t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 908099..908117 /Source="Nicolas_upshift_promotors" /id="U631" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.693306693306693" /psig="0.693306693306693" /xcortree=1182 /SigmaFactorBS="atgtttgctgccccgcttttgcttacctttgtatttgggAGT ATGctcagcggcaatgaTGATAAGGTGCGGCTTGCAatcgttgatcaggacgatacga t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 908100 /Source="Nicolas_upshifts" /id="U631" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.693306693306693" /psig="0.693306693306693" /xcortree=1182 /SigmaFactorBS="atgtttgctgccccgcttttgcttacctttgtatttgggAGT ATGctcagcggcaatgaTGATAAGGTGCGGCTTGCAatcgttgatcaggacgatacga t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" S_feature complement(909123..909197) /Source="Nicolas_S_feature" /locus_tag="new_909123_909197_c" /HighExp="LoTm, Sw, C90, HiOs, BC, MG 45, UNK1, Fru, S1, BI" /AntisenseName="yfiN" /AntisenseCor="-6.3486715356968801E-2" /AntisenseRegPval="-0.5" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.997" /TUlongSig="NA" /TUlongPSig="NA" /label="S284" downshifts complement(909166) /Source="Nicolas_upshifts" /id="D415" /incds=0 /nref=90 /ntot=257 /MaxReadThrough="1.41433" /MaxDrop="6.01369" /score="13.7314837" /energy="-11.5" /TU="U632" /idTUdmin="U632" /TUdmin="-22" /isTUend="TRUE" CDS complement(909198..909746) /gene="padR" /locus_tag="BSU_08340" /old_locus_tag="BSU08340" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:11073918, 17295427, 18326577, 21685295, 23189126, 27716049, 28027933" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11073918, 17295427, 18326577, 21685295, 23189126, 27716049, 28027933; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator of phenolic acid decarboxylase" /protein_id="NP_388715.1" /db_xref="EnsemblGenomes-Gn:BSU08340" /db_xref="EnsemblGenomes-Tr:CAB12663" /db_xref="GOA:P94443" /db_xref="InterPro:IPR005149" /db_xref="InterPro:IPR018309" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG12220" /db_xref="UniProtKB/Swiss-Prot:P94443" /translation="MRVLKYAILGLLRKGELSGYDITSYFKEELGQFWSAKHSQIYPE LKKLTDEGFITFRTTIQGTKLEKKMYTLTDSGKQELHDWLIRHQPIPETVKDEFMLKA YFISCLSRQEASDLFKDQLQKRQAKLSDLQGSYEKLMASAEPMSFSSPDFGHYLVLTK ALEREKNYVSWLESILAMIDKD*" gene complement(909198..909746) /gene="padR" /locus_tag="BSU_08340" /old_locus_tag="BSU08340" S_feature complement(909747..909826) /Source="Nicolas_S_feature" /locus_tag="new_909747_909826_c" /HighExp="LoTm, Cold, G180, GM-0.2, Oxctl, T5.0H, GM 25, T3.30H, MG 60, T4.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.997" /TUlongSig="NA" /TUlongPSig="NA" /label="S285" promotor_-10 complement(909815..909834) /Source="Nicolas_upshift_promotors" /id="U632" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.405594405594406" /psig="0.997002997002997" /xcortree=2251 /SigmaFactorBS="acaaaccttttatcttcatttccaaagagcccgGTTGTGttc ccttcctcccTTTTCTATAATAAGGGGAATaggcagttagaatcacagttgagcaccg g" /listShort="S285, padR, S284" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(909826) /Source="Nicolas_upshifts" /id="U632" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.405594405594406" /psig="0.997002997002997" /xcortree=2251 /SigmaFactorBS="acaaaccttttatcttcatttccaaagagcccgGTTGTGttc ccttcctcccTTTTCTATAATAAGGGGAATaggcagttagaatcacagttgagcaccg g" /listShort="S285, padR, S284" /GFF_Attribute="listLong" promotor_-35 complement(909848..909853) /Source="Nicolas_upshift_promotors" /id="U632" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.405594405594406" /psig="0.997002997002997" /xcortree=2251 /SigmaFactorBS="acaaaccttttatcttcatttccaaagagcccgGTTGTGttc ccttcctcccTTTTCTATAATAAGGGGAATaggcagttagaatcacagttgagcaccg g" /listShort="S285, padR, S284" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 909949..909952 /Source="Nicolas_upshift_promotors" /id="U633" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.927072927072927" /psig="0.998001998001998" /xcortree=2321 /SigmaFactorBS="tataaaagagatttaaatttaattttcagaaaaaATAGtaac gatattgatttTTTATATATAATAGGAAATTggtggtatgaaaattttttgggggaat a" /listShort="estB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 909968..909987 /Source="Nicolas_upshift_promotors" /id="U633" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.927072927072927" /psig="0.998001998001998" /xcortree=2321 /SigmaFactorBS="tataaaagagatttaaatttaattttcagaaaaaATAGtaac gatattgatttTTTATATATAATAGGAAATTggtggtatgaaaattttttgggggaat a" /listShort="estB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 909975 /Source="Nicolas_upshifts" /id="U633" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.927072927072927" /psig="0.998001998001998" /xcortree=2321 /SigmaFactorBS="tataaaagagatttaaatttaattttcagaaaaaATAGtaac gatattgatttTTTATATATAATAGGAAATTggtggtatgaaaattttttgggggaat a" /listShort="estB" /GFF_Attribute="listLong" CDS 910019..910651 /gene="estB" /locus_tag="BSU_08350" /old_locus_tag="BSU08350" /EC_number="3.1.1.3" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:11029590, 10913700, 21574267" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11029590, 10913700, 21574267; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="secreted esterase / acylglycerol lipase" /protein_id="NP_388716.1" /db_xref="EnsemblGenomes-Gn:BSU08350" /db_xref="EnsemblGenomes-Tr:CAB12664" /db_xref="GOA:Q79F14" /db_xref="InterPro:IPR002918" /db_xref="InterPro:IPR029058" /db_xref="SubtiList:BG11951" /db_xref="UniProtKB/Swiss-Prot:Q79F14" /translation="MKKVLMAFIICLSLILSVLAAPPSGAKAESVHNPVVLVHGISGA SYNFFAIKNYLISQGWQSNKLYAIDFYDKTGNNLNNGPQLASYVDRVLKETGAKKVDI VAHSMGGANTLYYIKYLGGGNKIQNVVTLGGANGLVSSTALPGTDPNQKILYTSIYSL NDQIVINSLSRLQGARNIQLYGIGHIGLLSNSQVNGYIKEGLNGGGLNTN*" gene 910019..910651 /gene="estB" /locus_tag="BSU_08350" /old_locus_tag="BSU08350" downshifts 910630 /Source="Nicolas_upshifts" /id="D416" /incds=0 /nref=7 /ntot=100 /MaxReadThrough="0.87881" /MaxDrop="2.6151" /score="0.223019698" /energy="-8.5" /TU="NA" /idTUdmin="U633" /TUdmin=88 /isTUend="FALSE" promotor_-35 910766..910771 /Source="Nicolas_upshift_promotors" /id="U634" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.492507492507492" /psig="0.984015984015984" /xcortree=3160 /SigmaFactorBS="tcatgcatacgtcaatttatgacatcaggcaCTTTTTcaaat agagcggaCATGTTAAGGTACAACCATCgatttctatcaatttgaaataaaaggagcg c" /listShort="yfiQ" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 910785..910804 /Source="Nicolas_upshift_promotors" /id="U634" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.492507492507492" /psig="0.984015984015984" /xcortree=3160 /SigmaFactorBS="tcatgcatacgtcaatttatgacatcaggcaCTTTTTcaaat agagcggaCATGTTAAGGTACAACCATCgatttctatcaatttgaaataaaaggagcg c" /listShort="yfiQ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 910795 /Source="Nicolas_upshifts" /id="U634" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.492507492507492" /psig="0.984015984015984" /xcortree=3160 /SigmaFactorBS="tcatgcatacgtcaatttatgacatcaggcaCTTTTTcaaat agagcggaCATGTTAAGGTACAACCATCgatttctatcaatttgaaataaaaggagcg c" /listShort="yfiQ" /GFF_Attribute="listLong" CDS 910840..911928 /gene="icaC" /locus_tag="BSU_08360" /old_locus_tag="BSU08360" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 15849754, 16850406, 24776724, 25935415, 27303652; Product type t : transporter" /codon_start=1 /transl_table=11 /product="acetyl-glucosamine metabolite exporter componentinvolved in biofilm formation" /protein_id="NP_388717.1" /db_xref="EnsemblGenomes-Gn:BSU08360" /db_xref="EnsemblGenomes-Tr:CAB12665" /db_xref="GOA:O31559" /db_xref="InterPro:IPR002656" /db_xref="SubtiList:BG12893" /db_xref="UniProtKB/Swiss-Prot:O31559" /translation="MQIKEIFMIRCISCLSVVLLHIISMVLMLQAEALADISHTVDSF RTLLMFSTPAFIFISEFLLARSYPDGVPDGFLKKRGKVIFVPFLFIAAIDALLMTSAM GGEVTFLAFVQKYLANVFLGNFIGYFILVIFQFYMLHMMFHEYLKKASPKWVLSISFV VTAAYLGYFSAASPAPASEEGGAFPFFWVPFAGWLFYFCLAYYCGKEYKRFLALLNQY RWVVYGAAIASGALVVTVSYVGEIGMISSKRPDIMLYSTSMIFLCFHLFSKMKHVPKI MMFISNYSFSIYLLHAYFMIIGYVLLLNMPEIPAVPAVLLLFAVCTAGPIMTSWALNK FKYGYLFVGKIYQPKQKKVTVEVRDHAG*" gene 910840..911928 /gene="icaC" /locus_tag="BSU_08360" /old_locus_tag="BSU08360" S_feature complement(911330..911718) /Source="Nicolas_S_feature" /locus_tag="new_911330_911718_c" /HighExp="S6, S8, S7, S5, LBGstat, H2O2, Mt0, Cold, G180, LPhT" /AntisenseName="yfiQ" /AntisenseCor="0.36913176163336098" /AntisenseRegPval="-9.4" /CDS_PredictionProba="NA" /TUshortSig="SigK" /TUshortPSig="0.976" /TUlongSig="NA" /TUlongPSig="NA" /label="S286" upshifts complement(911718) /Source="Nicolas_upshifts" /id="U635" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.976023976023976" /psig="0.976023976023976" /xcortree=1391 /SigmaFactorBS="agccggtacggcaggaatTTCGGGCATattcaaaagcaaCAC GTAGCCTATAATCATAAaataggcatgaagcagataaatcgaaaaggaatagttgctg a" /listShort="S286" /GFF_Attribute="listLong" promotor_-10 complement(911720..911739) /Source="Nicolas_upshift_promotors" /id="U635" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.976023976023976" /psig="0.976023976023976" /xcortree=1391 /SigmaFactorBS="agccggtacggcaggaatTTCGGGCATattcaaaagcaaCAC GTAGCCTATAATCATAAaataggcatgaagcagataaatcgaaaaggaatagttgctg a" /listShort="S286" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 complement(911752..911760) /Source="Nicolas_upshift_promotors" /id="U635" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.976023976023976" /psig="0.976023976023976" /xcortree=1391 /SigmaFactorBS="agccggtacggcaggaatTTCGGGCATattcaaaagcaaCAC GTAGCCTATAATCATAAaataggcatgaagcagataaatcgaaaaggaatagttgctg a" /listShort="S286" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(911964..912581) /gene="yfiR" /locus_tag="BSU_08370" /old_locus_tag="BSU08370" /function="16.3: Control" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:16862575" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16862575; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator (TetR/AcrR family)" /protein_id="NP_388718.1" /db_xref="EnsemblGenomes-Gn:BSU08370" /db_xref="EnsemblGenomes-Tr:CAB12666" /db_xref="GOA:O31560" /db_xref="InterPro:IPR001647" /db_xref="InterPro:IPR009057" /db_xref="InterPro:IPR036271" /db_xref="PDB:1RKT" /db_xref="SubtiList:BG12894" /db_xref="UniProtKB/Swiss-Prot:O31560" /translation="MSPKVTKEHKDKRQAEILEAAKTVFKRKGFELTTMKDVVEESGF SRGGVYLYFSSTEEMFRRIIETGLDEGLRKLDKSAEHQSVWASISSYLDELTEGLRDV ADTLAPVQFEYLVTAWRNEERRQYLEKRYDLFVERFSRLLQKGIDQGEFQPVQPLATI AKFFLNMNDGIIQNALYFDEEKADVSGLAESAKLYLKTVLQADEK*" gene complement(911964..912581) /gene="yfiR" /locus_tag="BSU_08370" /old_locus_tag="BSU08370" downshifts complement(911982) /Source="Nicolas_upshifts" /id="D417" /incds=0 /nref=29 /ntot=209 /MaxReadThrough="2.44114" /MaxDrop="4.07715" /score="22.1532141" /energy="-17.1" /TU="NA" /idTUdmin="U636" /TUdmin=0 /isTUend="TRUE" CDS complement(912547..913800) /gene="yfiS" /locus_tag="BSU_08380" /old_locus_tag="BSU08380" /function="16.1: Circulate" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 9811639, 15849754, 16850406, 16862575; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative efflux transporter" /protein_id="NP_388719.1" /db_xref="EnsemblGenomes-Gn:BSU08380" /db_xref="EnsemblGenomes-Tr:CAB12667" /db_xref="GOA:O31561" /db_xref="InterPro:IPR011701" /db_xref="InterPro:IPR020846" /db_xref="InterPro:IPR036259" /db_xref="SubtiList:BG12895" /db_xref="UniProtKB/Swiss-Prot:O31561" /translation="MEKPLFRNQKGLMTLLASQTISSLGDWLHILAVLTLAAFQLHAS PLDMSLLMMSFALPVIVLGPVSGLLADRFDRKTIMFLSEIGRALTVISCVYVSELWQL YVLLSVQSCFSSLFLPAKNGKLKELAPEAHIQQAVSVSSIIDNSSKIFGPALGGTLIA AFSIHSVFYINAGAFFLSAVILFFLPRDAFLQKANTPQEKTAALTSIKEGLQFLKRMP LLLTGLLTACVVLFVLQIGDSQAIILIRSFSGAPPELAGWCMAVSGAGMLLTAAITGR RRITSYLLYFSAGTLLLGLATGGAPFLSGMGIAGITLFIFAFFIMGAAFGLVHIPFQI LVQTTVPVDYSGRVFGAIQSATTLASILGMAGGGVLAEWIGVSLAFLVCGCLLIMIGL ITLIGKKIAESRRYLVTKSNKGAQG*" gene complement(912547..913800) /gene="yfiS" /locus_tag="BSU_08380" /old_locus_tag="BSU08380" promotor_-10 complement(912608..912627) /Source="Nicolas_upshift_promotors" /id="U636" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.918081918081918" /psig="0.998001998001998" /xcortree=3148 /SigmaFactorBS="tcggtgtatcacttgcttttcttgtctgtggcTGCTTGCTga tcatgattgggTTGATTACACTTATAGGTAAgaaaattgcagaaagcaggcgatatct t" /listShort="yfiR" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(912620) /Source="Nicolas_upshifts" /id="U636" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.918081918081918" /psig="0.998001998001998" /xcortree=3148 /SigmaFactorBS="tcggtgtatcacttgcttttcttgtctgtggcTGCTTGCTga tcatgattgggTTGATTACACTTATAGGTAAgaaaattgcagaaagcaggcgatatct t" /listShort="yfiR" /GFF_Attribute="listLong" promotor_-35 complement(912641..912648) /Source="Nicolas_upshift_promotors" /id="U636" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.918081918081918" /psig="0.998001998001998" /xcortree=3148 /SigmaFactorBS="tcggtgtatcacttgcttttcttgtctgtggcTGCTTGCTga tcatgattgggTTGATTACACTTATAGGTAAgaaaattgcagaaagcaggcgatatct t" /listShort="yfiR" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(913834..913853) /Source="Nicolas_upshift_promotors" /id="U637" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.492507492507492" /psig="0.99100899100899" /xcortree=2727 /SigmaFactorBS="cttctattcaatcttctcctttattttacaagaaaaaGATTG TATattgtgtctttttcCCATACAATTAAAAACGACActagtgtcattttaataatca g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(913852) /Source="Nicolas_upshifts" /id="U637" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.492507492507492" /psig="0.99100899100899" /xcortree=2727 /SigmaFactorBS="cttctattcaatcttctcctttattttacaagaaaaaGATTG TATattgtgtctttttcCCATACAATTAAAAACGACActagtgtcattttaataatca g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(913868..913875) /Source="Nicolas_upshift_promotors" /id="U637" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.492507492507492" /psig="0.99100899100899" /xcortree=2727 /SigmaFactorBS="cttctattcaatcttctcctttattttacaagaaaaaGATTG TATattgtgtctttttcCCATACAATTAAAAACGACActagtgtcattttaataatca g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" misc_feature 913879..913898 /Source="Nicolas_upshift_promotors" /id="U638" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.77022977022977" /psig="0.98901098901099" /xcortree=3204 /SigmaFactorBS="atgacactagtgtcgtttttaattgtatgggaaaaagacaca atatacaatctttTTCTTGTAAAATAAAGGAGAagattgaatagaagggagaacattc a" /listShort="yfiT" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 913884 /Source="Nicolas_upshifts" /id="U638" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.77022977022977" /psig="0.98901098901099" /xcortree=3204 /SigmaFactorBS="atgacactagtgtcgtttttaattgtatgggaaaaagacaca atatacaatctttTTCTTGTAAAATAAAGGAGAagattgaatagaagggagaacattc a" /listShort="yfiT" /GFF_Attribute="listLong" CDS 913924..914460 /gene="bstA" /locus_tag="BSU_08390" /old_locus_tag="BSU08390" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:15581359, 22059487, 24821014, 22720735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15581359, 22059487, 24821014, 22720735; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="bacillithiol S-transferase" /protein_id="NP_388720.1" /db_xref="EnsemblGenomes-Gn:BSU08390" /db_xref="EnsemblGenomes-Tr:CAB12668" /db_xref="GOA:O31562" /db_xref="InterPro:IPR023774" /db_xref="InterPro:IPR024775" /db_xref="InterPro:IPR034660" /db_xref="PDB:1RXQ" /db_xref="SubtiList:BG12896" /db_xref="UniProtKB/Swiss-Prot:O31562" /translation="MTSVNLSYPIGEYKPRESISKEQKDKWIQVLEEVPAKLKQAVEV MTDSQLDTPYRDGGWTVRQVVHHLADSHMNSYIRFKLSLTEETPAIRPYDEKAWSELK DSKTADPSGSLALLQELHGRWTALLRTLTDQQFKRGFYHPDTKEIITLENALGLYVWH SHHHIAHITELSRRMGWS*" gene 913924..914460 /gene="bstA" /locus_tag="BSU_08390" /old_locus_tag="BSU08390" CDS complement(914457..916013) /gene="yfiU" /locus_tag="BSU_08400" /old_locus_tag="BSU08400" /function="16.1: Circulate" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative efflux transporter" /protein_id="NP_388721.1" /db_xref="EnsemblGenomes-Gn:BSU08400" /db_xref="EnsemblGenomes-Tr:CAB12669" /db_xref="GOA:O31563" /db_xref="InterPro:IPR011701" /db_xref="InterPro:IPR020846" /db_xref="InterPro:IPR036259" /db_xref="SubtiList:BG12897" /db_xref="UniProtKB/Swiss-Prot:O31563" /translation="MSEALTEQKSQKWAISLFTIGVFMAALDNGIISAALTTINESFS VSPSWGSWGITLYTLGLSVSVPIVGKLSDRYGRKKLFLIEVCLFGLGSLLVALSQSFP LFLISRLIQALGGGGIFIIGSSHILATLPKEKQGKALGLLGAMNGMAAVLGPNIGSFL LDWTGSWHWLFLINLPIAVLLVVFGACFIAETKAPEAKRLDAAGIFLLSLSILAVMYG MTNLDGANLLHSLGNPEVYGCIIFGILCFAALISYEKRVEMRGGDPILAYSLLRNHMF QRTLIIGLLSGGLLAAVIFIPSYVEQYLGVPAAKAGYWMTPLALASGIGAWLGGALTD KKGPVKTVILSGIISCAGFALFPLWVTEKWEFVIASVAAGIGFGFLLGAPLNVLVSEA AKTNKGTALGTLSLVRQIGLTLAPTLYAGFITAGFDQIGDEINSRLSDSGYSEKAMQM IPEIDSSEVSSLQEQIERIPVPEVKTAISDAIHASVASGYDHLYAAAAVVSLLVIAAI SIPAFRRQKR*" gene complement(914457..916013) /gene="yfiU" /locus_tag="BSU_08400" /old_locus_tag="BSU08400" promotor_-10 complement(916035..916053) /Source="Nicolas_upshift_promotors" /id="U639" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.623376623376623" /psig="0.623376623376623" /xcortree=795 /SigmaFactorBS="tgtcatccgcaaactgcgggagcaggctttttttatttgaCA TTtagttcatttaaaatGAATAATATATTTCAAGTGaactaaaaggagttgacgaaaa t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(916052) /Source="Nicolas_upshifts" /id="U639" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.623376623376623" /psig="0.623376623376623" /xcortree=795 /SigmaFactorBS="tgtcatccgcaaactgcgggagcaggctttttttatttgaCA TTtagttcatttaaaatGAATAATATATTTCAAGTGaactaaaaggagttgacgaaaa t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(916069..916072) /Source="Nicolas_upshift_promotors" /id="U639" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.623376623376623" /psig="0.623376623376623" /xcortree=795 /SigmaFactorBS="tgtcatccgcaaactgcgggagcaggctttttttatttgaCA TTtagttcatttaaaatGAATAATATATTTCAAGTGaactaaaaggagttgacgaaaa t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(916124..916606) /gene="yfiV" /locus_tag="BSU_08410" /old_locus_tag="BSU08410" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 18990441; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative transcriptional regulator (MarR family)" /protein_id="NP_388722.1" /db_xref="EnsemblGenomes-Gn:BSU08410" /db_xref="EnsemblGenomes-Tr:CAB12670" /db_xref="GOA:O31564" /db_xref="InterPro:IPR000835" /db_xref="InterPro:IPR011991" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG12898" /db_xref="UniProtKB/Swiss-Prot:O31564" /translation="MEYNLHDTTVLNENILSSEEREIWVLYMKVLTSAGLGDVSEWMK LDMSMPQMKVLMLLNNHGTLKVSDIAEKMGASLSNTTGLLDRLEKSGFVKRSHSEEDR RSVVVQLTENAKKIFRGLYEKGHLKLKRSLELLSPEEKQAVYEGLSILSRALENAKKE *" gene complement(916124..916606) /gene="yfiV" /locus_tag="BSU_08410" /old_locus_tag="BSU08410" downshifts complement(916140) /Source="Nicolas_upshifts" /id="D418" /incds=0 /nref=58 /ntot=177 /MaxReadThrough="1.47849" /MaxDrop="4.15907" /score="27.2704527" /energy="-14.2" /TU="NA" /idTUdmin="U640" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(916631..916650) /Source="Nicolas_upshift_promotors" /id="U640" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.542457542457542" /psig="0.998001998001998" /xcortree=2019 /SigmaFactorBS="atttttcggacaaagtcccgcatgcggtttctgctcACTTTC TttcaggagtgaaaaTCGAGTAATATGGTAAGAGGagtgaatgatgaggaagtgatga a" /listShort="yfiV" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(916647) /Source="Nicolas_upshifts" /id="U640" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.542457542457542" /psig="0.998001998001998" /xcortree=2019 /SigmaFactorBS="atttttcggacaaagtcccgcatgcggtttctgctcACTTTC TttcaggagtgaaaaTCGAGTAATATGGTAAGAGGagtgaatgatgaggaagtgatga a" /listShort="yfiV" /GFF_Attribute="listLong" promotor_-35 complement(916665..916671) /Source="Nicolas_upshift_promotors" /id="U640" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.542457542457542" /psig="0.998001998001998" /xcortree=2019 /SigmaFactorBS="atttttcggacaaagtcccgcatgcggtttctgctcACTTTC TttcaggagtgaaaaTCGAGTAATATGGTAAGAGGagtgaatgatgaggaagtgatga a" /listShort="yfiV" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 916692..916699 /Source="Nicolas_upshift_promotors" /id="U641" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.544455544455544" /psig=1 /xcortree=2519 /SigmaFactorBS="tgaaagaaagtgagcagaaaccgcatgcgggACTTTGTCcga aaaataacggTAGTGTATAATGAGTTGGAGattattgggggagaggatcgaactagaa t" /listShort="mprF" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 916713..916732 /Source="Nicolas_upshift_promotors" /id="U641" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.544455544455544" /psig=1 /xcortree=2519 /SigmaFactorBS="tgaaagaaagtgagcagaaaccgcatgcgggACTTTGTCcga aaaataacggTAGTGTATAATGAGTTGGAGattattgggggagaggatcgaactagaa t" /listShort="mprF" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 916721 /Source="Nicolas_upshifts" /id="U641" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.544455544455544" /psig=1 /xcortree=2519 /SigmaFactorBS="tgaaagaaagtgagcagaaaccgcatgcgggACTTTGTCcga aaaataacggTAGTGTATAATGAGTTGGAGattattgggggagaggatcgaactagaa t" /listShort="mprF" /GFF_Attribute="listLong" CDS 916778..919348 /gene="mprF" /locus_tag="BSU_08425" /old_locus_tag="BSU08425" /EC_number="2.3.2.3" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:2139213, 2490162, 12427923, 14702396, 15849754, 16299297, 16850406, 17042784, 19074395, 21306448, 26261323" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 2139213, 2490162, 12427923, 14702396, 15849754, 16299297, 16850406, 17042784, 19074395, 21306448, 26261323; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="phosphatidylglycerol lysyltransferase involved in tRNA-dependent lysinylation of phospholipids" /protein_id="YP_003097695.1" /db_xref="EnsemblGenomes-Gn:BSU08425" /db_xref="EnsemblGenomes-Tr:CAX52582" /db_xref="GOA:C0H3X7" /db_xref="InterPro:IPR016181" /db_xref="InterPro:IPR022791" /db_xref="InterPro:IPR024320" /db_xref="UniProtKB/Swiss-Prot:C0H3X7" /translation="MLIKKNALSILKIVFPIAVLLFVIYQSKKELTNLSFKRTLMVIN GLERTDLFMLVLIGLLAVAAMSLYDYVLKYSLRLSITNGKVFRVSWIANSFNNVLGFG GLAGVGLRMMFYKEHTKDHKALVKGIAWLTSSMLLGLSVFSIFVAARVLPVDEVIHEK PWLWAVVIGFALILPLSLAVSKIKDRKAGDEENADKVKNPIFAYIGASVVEWLMAGTV IYFALFAMGIHADIRYVFGVFVIAAIGGMISLVPGGFGSFDLLFLLGMEQLGYHQEAI VTSIVLYRLAYSFIPFILGLFFAAGDLTENTMKRLETNPRIAPAIETTNVLLVVQRAV LVRILQGSLSLIVFVAGLIVLASVSLPIDRLTVIPHIPRPALLLFNGLSLSSALILLI LPIELYKRTKRSYTMAITALVGGFVFSFLKGLNISAIFVLPMIIVLLVLLKKQFVREQ ASYTLGQLIFAVALFTVALFNYNLIAGFIWDRMKKVLRHEYFVHSTSHITHATIMAII IVPLFFLIFTVVYHKRTKPIGEKADPERLAAFLNEKGGNALSHLGFLGDKRFYFSSDG NALLLFGKIARRLVVLGDPSGQRESFPLVLEEFLNEAHQKGFSVLFYQIEREDMALYH DFGYNFFKLGEEAYVDLNTFTLTGKKKAGLRAINNRFEREEYTFHVDHPPFSDAFLEE LKQISDEWLGSKKEKGFSLGFFDPSYLQKAPIAYMKNAEGEIVAFANVMPMYQEGEIS VDLMRYRGDAPNGIMDALFIRMFLWAKEEGCTSFNMGMAPLANVGTAFTSFWSERFAA VIFNNVRYMYSFSGLRAFKEKYKPEWRGKYLAYRKNRSLSVTMFLVTRLIGKSKKDSV *" gene 916778..919348 /gene="mprF" /locus_tag="BSU_08425" /old_locus_tag="BSU08425" downshifts 919319 /Source="Nicolas_upshifts" /id="D419" /incds=0 /nref=121 /ntot=252 /MaxReadThrough="1.79352" /MaxDrop="5.78159" /score="49.2396824" /energy="-16.1" /TU="NA" /idTUdmin="U641" /TUdmin=0 /isTUend="TRUE" CDS complement(919366..920343) /gene="sxzY" /locus_tag="BSU_08440" /old_locus_tag="BSU08440" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1c: Function from experimental evidences in the studied genus; PubMedId: 12354229, 19254027, 24606332; Product type t: transporter" /codon_start=1 /transl_table=11 /product="xenosiderophore schizokinen (dihydroxamate) transporter binding lipoprotein" /protein_id="NP_388725.1" /db_xref="EnsemblGenomes-Gn:BSU08440" /db_xref="EnsemblGenomes-Tr:CAB12673" /db_xref="GOA:O31567" /db_xref="InterPro:IPR002491" /db_xref="SubtiList:BG12901" /db_xref="UniProtKB/Swiss-Prot:O31567" /translation="MKKHISMLFVFLMAVMVLSACNSSESSSNSEVSSSKTRTVKHAM GTSDNIPANPKRIVVLTNEGTEALLALGIKPVGAVKSWKGDPWYDYLKDDMKGVKNVG LETEPNVEAIAELKPDLIIGNKVRQEKIYDQLNAIAPTVFAESLAGNWKDNLTLYANA VNKADKGKEVIADFDKRVSDLKNKLGDQTNKTVSVVRFLSGESRIYYTDSFPGIILDQ LGFKRPEKQVELFKKQKDQFTFSTDSKESIPDMDADVLFYFTYKADNAKENEKWANQW TSSSLWKNLKAVKSGNAHEVDDVVWTTAGGIKAANYLLDDIETYFLKTK*" gene complement(919366..920343) /gene="sxzY" /locus_tag="BSU_08440" /old_locus_tag="BSU08440" downshifts complement(919377) /Source="Nicolas_upshifts" /id="D420" /incds=0 /nref=165 /ntot=248 /MaxReadThrough="1.28876" /MaxDrop="7.70135" /score="35.2605181" /energy="-16.1" /TU="NA" /idTUdmin="U643" /TUdmin="-4" /isTUend="TRUE" promotor_-35 920358..920365 /Source="Nicolas_upshift_promotors" /id="U642" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.458541458541459" /psig="0.998001998001998" /xcortree=2100 /SigmaFactorBS="gcatgctgatatgctttttcatctttttcctcccaaTATTGA AAttcattatcatttaGATCATAATAAGCAGTGTTAagagtgtcaatccctaattgag g" /listShort="S287, yfiZ, yfhA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(920370..920389) /Source="Nicolas_upshift_promotors" /id="U643" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.96003996003996" /psig=1 /xcortree=2109 /SigmaFactorBS="tgtaatgtttgtttttgagaataatcctcaattaggGATTGA CActcttaacactgctTATTATGATCTAAATGATAAtgaatttcaatattgggaggaa a" /listShort="yfiY" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-10 920380..920399 /Source="Nicolas_upshift_promotors" /id="U642" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.458541458541459" /psig="0.998001998001998" /xcortree=2100 /SigmaFactorBS="gcatgctgatatgctttttcatctttttcctcccaaTATTGA AAttcattatcatttaGATCATAATAAGCAGTGTTAagagtgtcaatccctaattgag g" /listShort="S287, yfiZ, yfhA" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 920382..920473 /Source="Nicolas_S_feature" /locus_tag="new_920382_920473" /HighExp="dia0, Lbexp, LBGexp, H2O2, G150, GM 10, Oxctl, dia15, Paraq, GM 5" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.998" /TUlongSig="NA" /TUlongPSig="NA" /label="S287" upshifts 920382 /Source="Nicolas_upshifts" /id="U642" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.458541458541459" /psig="0.998001998001998" /xcortree=2100 /SigmaFactorBS="gcatgctgatatgctttttcatctttttcctcccaaTATTGA AAttcattatcatttaGATCATAATAAGCAGTGTTAagagtgtcaatccctaattgag g" /listShort="S287, yfiZ, yfhA" /GFF_Attribute="listLong" upshifts complement(920387) /Source="Nicolas_upshifts" /id="U643" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.96003996003996" /psig=1 /xcortree=2109 /SigmaFactorBS="tgtaatgtttgtttttgagaataatcctcaattaggGATTGA CActcttaacactgctTATTATGATCTAAATGATAAtgaatttcaatattgggaggaa a" /listShort="yfiY" /GFF_Attribute="listLong" promotor_-35 complement(920404..920411) /Source="Nicolas_upshift_promotors" /id="U643" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.96003996003996" /psig=1 /xcortree=2109 /SigmaFactorBS="tgtaatgtttgtttttgagaataatcctcaattaggGATTGA CActcttaacactgctTATTATGATCTAAATGATAAtgaatttcaatattgggaggaa a" /listShort="yfiY" /GFF_Attribute="listLong" /label="promotor_-35" CDS 920474..921475 /gene="sxzZ" /locus_tag="BSU_08450" /old_locus_tag="BSU08450" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:12354229, 15849754, 16672620, 16850406, 19254027" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12354229, 15849754, 16672620, 16850406, 19254027; Product type t : transporter" /codon_start=1 /transl_table=11 /product="xenosiderophore schizokinen (dihydroxamate) transporter (permease)" /protein_id="NP_388726.1" /db_xref="EnsemblGenomes-Gn:BSU08450" /db_xref="EnsemblGenomes-Tr:CAB12674" /db_xref="GOA:O31568" /db_xref="InterPro:IPR000522" /db_xref="InterPro:IPR035568" /db_xref="SubtiList:BG12902" /db_xref="UniProtKB/Swiss-Prot:O31568" /translation="MICKKASSKWIVLVCLIFILLTAVCASVVYGYTGTSWRQVYQAF TSFNGTNEHVIIKDVRLPRALVATVVGASLAAAGALMQALTKNPLASPGIFGINAGAG FFIVAGSFFLHIQSPQALVWSSFLGAAFTAAIVYAAGSLGREGLTPIKLTLAGAAMAA MFSSLTQGLLSVNELELAQVLFWLTGSVQGRSLDLLMTMFPYAAAALVICFFLGQKIN LLVMGEDVAKGLGQKTGLLKFVMALCVVMLAGSAVAIAGPISFIGIIIPHFARFVVGN DYRWVLPFSAVLGAILLVCADIGARYIIMPQEVPVGVMTAIIGMPVFVYIARRGAKL* " gene 920474..921475 /gene="sxzZ" /locus_tag="BSU_08450" /old_locus_tag="BSU08450" CDS 921472..922503 /gene="sxzA" /locus_tag="BSU_08460" /old_locus_tag="BSU08460" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:12354229, 15849754, 16672620, 16850406, 19254027" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12354229, 15849754, 16672620, 16850406, 19254027; Product type t : transporter" /codon_start=1 /transl_table=11 /product="xenosiderophore schizokinen (dihydroxamate) transporter (permease)" /protein_id="NP_388727.1" /db_xref="EnsemblGenomes-Gn:BSU08460" /db_xref="EnsemblGenomes-Tr:CAB12675" /db_xref="GOA:O31569" /db_xref="InterPro:IPR000522" /db_xref="InterPro:IPR035568" /db_xref="SubtiList:BG12876" /db_xref="UniProtKB/Swiss-Prot:O31569" /translation="MKLRFGVTAAEKKAWIVFLVLLGLTAAVLIISAGLGQRFIPPWD VAKTFFGAGSKLDELMIMSFRMPRILTALCAGVCLAAAGAILQGLVRNPLASPDIIGI TGGAAVAVVLLMMFFSDRSSSLTISLSWLPAAAFIGASAVGLIVYLLAYKNGASTFRL VLIGIGFSMSAQAMTTLLMIKGPIYRASQANVYITGSVYGSNWQHVKIAIILSVILLF ICFVALKNMNIQVLGEDIAAGAGSAVQRNRFFLLLLSTALTGCAVSVAGTIGFVGLMA PHIARRLVGSSYGALLPASALIGALLVLTADIVGRTLFAPVEVPAGVFTAAIGAPYFI YLLYKTRNS*" gene 921472..922503 /gene="sxzA" /locus_tag="BSU_08460" /old_locus_tag="BSU08460" downshifts 922484 /Source="Nicolas_upshifts" /id="D421" /incds=0 /nref=24 /ntot=154 /MaxReadThrough="3.26686" /MaxDrop="4.27732" /score="19.6751667" /energy="-12.8" /TU="NA" /idTUdmin="U642" /TUdmin="-3" /isTUend="TRUE" promotor_-35 922554..922556 /Source="Nicolas_upshift_promotors" /id="U644" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.945054945054945" /psig="0.999000999001" /xcortree=2943 /SigmaFactorBS="attttcttaaaaaagaaaatgggtttttttgataatgacTGA agattcgtaattattTTTGCTATACTGACAGAGACattgataaagaaagggcggcaga t" /listShort="yfhB, yfhC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 922572..922591 /Source="Nicolas_upshift_promotors" /id="U644" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.945054945054945" /psig="0.999000999001" /xcortree=2943 /SigmaFactorBS="attttcttaaaaaagaaaatgggtttttttgataatgacTGA agattcgtaattattTTTGCTATACTGACAGAGACattgataaagaaagggcggcaga t" /listShort="yfhB, yfhC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 922575 /Source="Nicolas_upshifts" /id="U644" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.945054945054945" /psig="0.999000999001" /xcortree=2943 /SigmaFactorBS="attttcttaaaaaagaaaatgggtttttttgataatgacTGA agattcgtaattattTTTGCTATACTGACAGAGACattgataaagaaagggcggcaga t" /listShort="yfhB, yfhC" /GFF_Attribute="listLong" CDS 922618..923499 /gene="yfhB" /locus_tag="BSU_08470" /old_locus_tag="BSU08470" /EC_number="5.1.-.-" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative isomerase" /protein_id="NP_388728.1" /db_xref="EnsemblGenomes-Gn:BSU08470" /db_xref="EnsemblGenomes-Tr:CAB12676" /db_xref="GOA:O31570" /db_xref="InterPro:IPR003719" /db_xref="SubtiList:BG12877" /db_xref="UniProtKB/Swiss-Prot:O31570" /translation="MKEAEVLKYEAFTSSPGKGNPAGVVLQGDDYTEDEMQIIAERAG YSETSFIRKSESADLELRYFTPGHEMNLCGHATVASLYALCEKGMLESGKTYSIQTKA GILPVKISEKDGRIHITLEQASPQFKPFTGDRKKLADALGITDEDFHEDLPIVFGSTG IWTAIVPLKSLEASKKMVPDNKQFPEVLVDLPKASVHPFTFETVHPDSDLHGRHFSSP YSGTIEDPVTGTASGVMGAYMKHYGNAEQHKFIIEQGQEIGKDGKVEIEMNEAGGHVK VNMTGTAVYSETRILKI*" gene 922618..923499 /gene="yfhB" /locus_tag="BSU_08470" /old_locus_tag="BSU08470" promotor_-35 923510..923517 /Source="Nicolas_upshift_promotors" /id="U645" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.719280719280719" /psig="0.998001998001998" /xcortree=2110 /SigmaFactorBS="cgtattcttaaaatctaatacggatgatGGTTTACAaaaaga tgcactttcCGTTATCATTATGAAATGATaatcattttcaattgcataggaaggtgag a" /listShort="yfhC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 923533..923552 /Source="Nicolas_upshift_promotors" /id="U645" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.719280719280719" /psig="0.998001998001998" /xcortree=2110 /SigmaFactorBS="cgtattcttaaaatctaatacggatgatGGTTTACAaaaaga tgcactttcCGTTATCATTATGAAATGATaatcattttcaattgcataggaaggtgag a" /listShort="yfhC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 923542 /Source="Nicolas_upshifts" /id="U645" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.719280719280719" /psig="0.998001998001998" /xcortree=2110 /SigmaFactorBS="cgtattcttaaaatctaatacggatgatGGTTTACAaaaaga tgcactttcCGTTATCATTATGAAATGATaatcattttcaattgcataggaaggtgag a" /listShort="yfhC" /GFF_Attribute="listLong" CDS 923587..924171 /gene="yfhC" /locus_tag="BSU_08480" /old_locus_tag="BSU08480" /EC_number="1.6.99.-" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 12354229, 22287527; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative oxidoreductase (nitroreductase family)" /protein_id="NP_388729.1" /db_xref="EnsemblGenomes-Gn:BSU08480" /db_xref="EnsemblGenomes-Tr:CAB12677" /db_xref="GOA:O31571" /db_xref="InterPro:IPR000415" /db_xref="InterPro:IPR026021" /db_xref="InterPro:IPR029479" /db_xref="SubtiList:BG12878" /db_xref="UniProtKB/Swiss-Prot:O31571" /translation="MPQTEQIHQHSVLRDIIRSRRSIRKFKQEPVPSAVILDMLETAK YAPNHRVTEPWRFIYVSSETGKANLINTFAAFSKKSKPDMTEEKLQNFKNTLGRVPGF LLVVFQEDENERARDDDFAATSSLIQNLQLLAWEKGIGMVWKSGKILYDKEVHQAFGL QDNERFAAIIQTGYPDEAPEVKKRTPIRDRFTEM*" gene 923587..924171 /gene="yfhC" /locus_tag="BSU_08480" /old_locus_tag="BSU08480" downshifts 924158 /Source="Nicolas_upshifts" /id="D422" /incds=0 /nref=208 /ntot=262 /MaxReadThrough="3.27483" /MaxDrop="6.40857" /score="21.7703837" /energy="-18.2" /TU="U645" /idTUdmin="U644" /TUdmin="-1" /isTUend="TRUE" CDS complement(924210..924401) /gene="yfhD" /locus_tag="BSU_08490" /old_locus_tag="BSU08490" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_388730.1" /db_xref="EnsemblGenomes-Gn:BSU08490" /db_xref="EnsemblGenomes-Tr:CAB12678" /db_xref="InterPro:IPR025435" /db_xref="SubtiList:BG12879" /db_xref="UniProtKB/Swiss-Prot:O31572" /translation="MGRNHIHKNRDKNKQKLPQVPDALKRETDGVYEEYSTELADADD REAQERAKAADNRAKKKSR*" gene complement(924210..924401) /gene="yfhD" /locus_tag="BSU_08490" /old_locus_tag="BSU08490" downshifts complement(924228) /Source="Nicolas_upshifts" /id="D423" /incds=0 /nref=65 /ntot=197 /MaxReadThrough="0.436919999999999" /MaxDrop="8.51174" /score="30.1998663" /energy="-18.2" /TU="NA" /idTUdmin="U649" /TUdmin=7 /isTUend="TRUE" upshifts complement(924433) /Source="Nicolas_upshifts" /id="U646" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=840 /SigmaFactorBS="cggaaaaagctgctaagcggaagtaGGAATACatagcccctt aaaaCCAAATACTATAtttgtttgatatcactttttagggggaatttgatatgggcag a" /listShort="yfhD" /GFF_Attribute="listLong" promotor_-10 complement(924436..924447) /Source="Nicolas_upshift_promotors" /id="U646" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=840 /SigmaFactorBS="cggaaaaagctgctaagcggaagtaGGAATACatagcccctt aaaaCCAAATACTATAtttgtttgatatcactttttagggggaatttgatatgggcag a" /listShort="yfhD" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 complement(924462..924468) /Source="Nicolas_upshift_promotors" /id="U646" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=840 /SigmaFactorBS="cggaaaaagctgctaagcggaagtaGGAATACatagcccctt aaaaCCAAATACTATAtttgtttgatatcactttttagggggaatttgatatgggcag a" /listShort="yfhD" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(924468..924578) /gene="yfhE" /locus_tag="BSU_08500" /old_locus_tag="BSU08500" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="NP_388731.1" /db_xref="EnsemblGenomes-Gn:BSU08500" /db_xref="EnsemblGenomes-Tr:CAB12679" /db_xref="InterPro:IPR025437" /db_xref="SubtiList:BG12880" /db_xref="UniProtKB/Swiss-Prot:O31573" /translation="MEKKREKHQQGANLKKMQEVLYSGEFKKAEKAAKRK*" gene complement(924468..924578) /gene="yfhE" /locus_tag="BSU_08500" /old_locus_tag="BSU08500" promotor_-10 complement(924607..924618) /Source="Nicolas_upshift_promotors" /id="U647" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=1140 /SigmaFactorBS="actctcacagctgatagcggaccgaaagacTGTATAAaaaca gcaggaagcGTCAACCTTAAGaataacatggttgaaggaggtcctttttatggaaaaa a" /listShort="yfhE, yfhD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(924609) /Source="Nicolas_upshifts" /id="U647" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=1140 /SigmaFactorBS="actctcacagctgatagcggaccgaaagacTGTATAAaaaca gcaggaagcGTCAACCTTAAGaataacatggttgaaggaggtcctttttatggaaaaa a" /listShort="yfhE, yfhD" /GFF_Attribute="listLong" promotor_-35 complement(924633..924639) /Source="Nicolas_upshift_promotors" /id="U647" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=1140 /SigmaFactorBS="actctcacagctgatagcggaccgaaagacTGTATAAaaaca gcaggaagcGTCAACCTTAAGaataacatggttgaaggaggtcctttttatggaaaaa a" /listShort="yfhE, yfhD" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(924633..925544) /gene="yfhF" /locus_tag="BSU_08510" /old_locus_tag="BSU08510" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative nucleotide-or NAD-binding protein" /protein_id="NP_388732.1" /db_xref="EnsemblGenomes-Gn:BSU08510" /db_xref="EnsemblGenomes-Tr:CAB12680" /db_xref="GOA:O31574" /db_xref="InterPro:IPR001509" /db_xref="InterPro:IPR010099" /db_xref="InterPro:IPR013549" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG12881" /db_xref="UniProtKB/Swiss-Prot:O31574" /translation="MNIAMTGGTGFLGQHLTGVLTRQGHHVYILSRNARETEQKNMTY VQWLSEGAAPEQELPHIDVWINLAGKSIFGRWTEKTKQHILSSRINATREVQRLIQKQ KEKPKTLIQASAVGIYGTSLEKTFTEDSATSDEDFLSHTAHLWEKEGQHIEAMGIRTV YARFGVMLGEKGALPLMILPYKFLAGGTIGTGRQWLSWIHVEDAAQMIRYAVENAGIS GPMNVTAPNPVDMKQFGKTIARVKHRPHWLPVPEFFLSKALGEMSLLIVKGQRALPKK AITSGFRFTYSDLEFALSQLIADRKTV*" gene complement(924633..925544) /gene="yfhF" /locus_tag="BSU_08510" /old_locus_tag="BSU08510" promotor_-35 925430..925433 /Source="Nicolas_upshift_promotors" /id="U648" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.531468531468531" /psig="0.999000999001" /xcortree=2741 /SigmaFactorBS="acagccattggacatatgtcatatttttttGTTCagtttccc ttgcgtttCTTGATAAAATATAAACATGgtgtccctggcgggtaagaacgcctgtcag a" /listShort="S288, recX, yfhH" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 925450..925469 /Source="Nicolas_upshift_promotors" /id="U648" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.531468531468531" /psig="0.999000999001" /xcortree=2741 /SigmaFactorBS="acagccattggacatatgtcatatttttttGTTCagtttccc ttgcgtttCTTGATAAAATATAAACATGgtgtccctggcgggtaagaacgcctgtcag a" /listShort="S288, recX, yfhH" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 925460..925632 /Source="Nicolas_S_feature" /locus_tag="new_925460_925632" /HighExp="LBGstat, Lbtran, T1.30H, T2.0H, T2.30H, M9-stat, T1.0H, T3.0H, Sw, G180" /AntisenseName="yfhF" /AntisenseCor="-5.3501479327985699E-2" /AntisenseRegPval="-0.4" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S288" upshifts 925460 /Source="Nicolas_upshifts" /id="U648" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.531468531468531" /psig="0.999000999001" /xcortree=2741 /SigmaFactorBS="acagccattggacatatgtcatatttttttGTTCagtttccc ttgcgtttCTTGATAAAATATAAACATGgtgtccctggcgggtaagaacgcctgtcag a" /listShort="S288, recX, yfhH" /GFF_Attribute="listLong" promotor_-10 complement(925566..925584) /Source="Nicolas_upshift_promotors" /id="U649" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.988011988011988" /psig="0.988011988011988" /xcortree=135 /SigmaFactorBS="aacggcatcttaatctcccttctcaggcctgaaacgCGTTTT CttttattacaatgAGGTAAAGTATATTTATTAgaacgatgaggagagatgttcatga a" /listShort="yfhF, yfhE, yfhD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(925580) /Source="Nicolas_upshifts" /id="U649" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.988011988011988" /psig="0.988011988011988" /xcortree=135 /SigmaFactorBS="aacggcatcttaatctcccttctcaggcctgaaacgCGTTTT CttttattacaatgAGGTAAAGTATATTTATTAgaacgatgaggagagatgttcatga a" /listShort="yfhF, yfhE, yfhD" /GFF_Attribute="listLong" promotor_-35 complement(925598..925604) /Source="Nicolas_upshift_promotors" /id="U649" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.988011988011988" /psig="0.988011988011988" /xcortree=135 /SigmaFactorBS="aacggcatcttaatctcccttctcaggcctgaaacgCGTTTT CttttattacaatgAGGTAAAGTATATTTATTAgaacgatgaggagagatgttcatga a" /listShort="yfhF, yfhE, yfhD" /GFF_Attribute="listLong" /label="promotor_-35" CDS 925633..926427 /gene="recX" /locus_tag="BSU_08520" /old_locus_tag="BSU08520" /function="16.3: Control" /function="16.9: Replicate" /experiment="publication(s) with functional evidences, PMID:8946165, 10869079, 12547390, 23284295, 24285298" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8946165, 10869079, 12547390, 23284295, 24285298; Product type r: regulator" /codon_start=1 /transl_table=11 /product="regulatory protein RecX" /protein_id="NP_388733.1" /db_xref="EnsemblGenomes-Gn:BSU08520" /db_xref="EnsemblGenomes-Tr:CAB12681" /db_xref="GOA:O31575" /db_xref="InterPro:IPR003783" /db_xref="InterPro:IPR036388" /db_xref="SubtiList:BG12882" /db_xref="UniProtKB/Swiss-Prot:O31575" /translation="MPFITKISTQKKNTERFNIFLDDKYAFSVDADVLVKFELKKGKE LDDLDIIEIQYGDEVKKGFNRALDFLSYRMRSTKEVEDHLKKKETSPPVIAEVIHRLN DYKYLNDQEFAAAYVSTHKKTNGKGPDVLFRELRAKGIDDDTIKEALSSFSFEDQTRE AVKHVEKLLKKDKKLSTKELKQRAQLQLQRKGFSFDVISAAMDQIEYENDEDTEKEAL RLHAEKAFRKYRYDGSYESAMKVKQFLFRKGFSLDLIEQLLQEEEY*" gene 925633..926427 /gene="recX" /locus_tag="BSU_08520" /old_locus_tag="BSU08520" CDS 926429..926743 /gene="yfhH" /locus_tag="BSU_08530" /old_locus_tag="BSU08530" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 22720735" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_388734.1" /db_xref="EnsemblGenomes-Gn:BSU08530" /db_xref="EnsemblGenomes-Tr:CAB12682" /db_xref="InterPro:IPR014938" /db_xref="InterPro:IPR036289" /db_xref="PDB:1SF9" /db_xref="SubtiList:BG12883" /db_xref="UniProtKB/Swiss-Prot:O31576" /translation="MEKRYSQMTPHELNTEIALLSEKARKAEQHGIINELAVLERKIT MAKAYLLNPEDYSPGETYRVENTEDEFTISYLNGVFAWGYRTSSPQQEEALPISVLQE KE*" gene 926429..926743 /gene="yfhH" /locus_tag="BSU_08530" /old_locus_tag="BSU08530" S_feature complement(926651..926919) /Source="Nicolas_S_feature" /locus_tag="new_926651_926919_c" /HighExp="S8, S6, S5, S7, C30, S4, nit, ferm, BT, G135" /AntisenseName="yfhH" /AntisenseCor="-0.53569713251514905" /AntisenseRegPval="-20.7" /CDS_PredictionProba="NA" /TUshortSig="NA" /TUshortPSig="NA" /TUlongSig="NA" /TUlongPSig="NA" /label="S289" downshifts 926733 /Source="Nicolas_upshifts" /id="D424" /incds=0 /nref=71 /ntot=206 /MaxReadThrough="2.93348" /MaxDrop="5.2859" /score="24.7235138" /energy="-11.6" /TU="NA" /idTUdmin="U648" /TUdmin=0 /isTUend="TRUE" promotor_-35 926817..926822 /Source="Nicolas_upshift_promotors" /id="U650" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.460539460539461" /psig=1 /xcortree=2471 /SigmaFactorBS="cagcacatttacacgaattcttaaagaaaaaatcATTGAAtt cacttgaaaaatcTTTTAAGATGAAACTCGTTGttttttaaaatcaaaggaggcgatg a" /listShort="yfhI, S290, S291, yfhJ" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 926838..926857 /Source="Nicolas_upshift_promotors" /id="U650" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.460539460539461" /psig=1 /xcortree=2471 /SigmaFactorBS="cagcacatttacacgaattcttaaagaaaaaatcATTGAAtt cacttgaaaaatcTTTTAAGATGAAACTCGTTGttttttaaaatcaaaggaggcgatg a" /listShort="yfhI, S290, S291, yfhJ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 926843 /Source="Nicolas_upshifts" /id="U650" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.460539460539461" /psig=1 /xcortree=2471 /SigmaFactorBS="cagcacatttacacgaattcttaaagaaaaaatcATTGAAtt cacttgaaaaatcTTTTAAGATGAAACTCGTTGttttttaaaatcaaaggaggcgatg a" /listShort="yfhI, S290, S291, yfhJ" /GFF_Attribute="listLong" CDS 926886..928079 /gene="yfhI" /locus_tag="BSU_08540" /old_locus_tag="BSU08540" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406, 22226636; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative efflux transporter" /protein_id="NP_388735.1" /db_xref="EnsemblGenomes-Gn:BSU08540" /db_xref="EnsemblGenomes-Tr:CAB12683" /db_xref="GOA:O31577" /db_xref="InterPro:IPR011701" /db_xref="InterPro:IPR020846" /db_xref="InterPro:IPR036259" /db_xref="SubtiList:BG12884" /db_xref="UniProtKB/Swiss-Prot:O31577" /translation="MSIKNPSVKFIIFVLMICTFSIGYTEYAVMGILTSIANDFHIQV SSAGLLVTAYAASVCLTGPLVTIISVKLPRKPVLLGLMAIFILSNLMSALAPNFAVLA ISRILSASIHGAFFAIAMVFASEMVPPEKRAAAAASMNGGLTVALMLGVPFGSYLGDV LNWRAVFSIITALGVIGFLGLMAAVPNRKPKVIPMLMNEWGVFKHKQVLFSFAITILG YSGVFIAYTFIEPILRHSAGFSTVGITGALFAYGLGGVAGNFFAGKVPLPLLTRTMIG VMIGLIGVLAVFPYIAIYPAAAIVATFLFGACAFGTPPLLQTKVISSSEGGTTIAAAV SVSAFNLANALGAWIGGMILNGTGSYSWLFAGGALMTACGLVLSTFAHLSEKKSVYEY QVNKG*" gene 926886..928079 /gene="yfhI" /locus_tag="BSU_08540" /old_locus_tag="BSU08540" S_feature 928080..928314 /Source="Nicolas_S_feature" /locus_tag="new_928080_928314" /HighExp="G180, Paraq, C30, Oxctl, H2O2, G135, G150, S8, Heat, LBGstat" /AntisenseName="sspK" /AntisenseCor="1.9886505145521101E-2" /AntisenseRegPval="-0.1" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S290" CDS complement(928112..928264) /gene="sspK" /locus_tag="BSU_08550" /old_locus_tag="BSU08550" /function="16.5: Explore" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:10806362" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10806362; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="small acid-soluble spore protein" /protein_id="YP_054573.1" /db_xref="EnsemblGenomes-Gn:BSU08550" /db_xref="EnsemblGenomes-Tr:CAE01449" /db_xref="GOA:Q7WY75" /db_xref="InterPro:IPR012611" /db_xref="SubtiList:BG14175" /db_xref="UniProtKB/Swiss-Prot:Q7WY75" /translation="MVRNKEKGFPYENENKFQGEPRAKDDYASKRADGSINQHPQERM RASGKR*" gene complement(928112..928264) /gene="sspK" /locus_tag="BSU_08550" /old_locus_tag="BSU08550" downshifts complement(928129) /Source="Nicolas_upshifts" /id="D425" /incds=0 /nref=24 /ntot=45 /MaxReadThrough="2.36419" /MaxDrop="4.9889" /score="20.2715496" /energy="-12.3" /TU="NA" /idTUdmin="U652" /TUdmin=0 /isTUend="TRUE" promotor_-35 928293..928300 /Source="Nicolas_upshift_promotors" /id="U651" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.924075924075924" /psig="0.995004995004995" /xcortree=2031 /SigmaFactorBS="tcggaccatgtcatatccccctaggttcgagatcaaaAAGTT GCGtcttttcagatgaAGACGTAAGGTTAGTATATGgagaacaccacgtaataaagcg t" /listShort="S291, yfhJ" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 928314..928333 /Source="Nicolas_upshift_promotors" /id="U651" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.924075924075924" /psig="0.995004995004995" /xcortree=2031 /SigmaFactorBS="tcggaccatgtcatatccccctaggttcgagatcaaaAAGTT GCGtcttttcagatgaAGACGTAAGGTTAGTATATGgagaacaccacgtaataaagcg t" /listShort="S291, yfhJ" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 928316..928388 /Source="Nicolas_S_feature" /locus_tag="new_928316_928388" /HighExp="dia5, LPhT, Diami, dia15, Etha, T0.30H, H2O2, LBGstat, BC, Salt" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="0.995, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S291" upshifts 928316 /Source="Nicolas_upshifts" /id="U651" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.924075924075924" /psig="0.995004995004995" /xcortree=2031 /SigmaFactorBS="tcggaccatgtcatatccccctaggttcgagatcaaaAAGTT GCGtcttttcagatgaAGACGTAAGGTTAGTATATGgagaacaccacgtaataaagcg t" /listShort="S291, yfhJ" /GFF_Attribute="listLong" promotor_-10 complement(928323..928334) /Source="Nicolas_upshift_promotors" /id="U652" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=867 /SigmaFactorBS="ttcatgtgtgcagtctcctttcttcaggaaaaaaataaCGCT TTAttacgtggtgttctCCATATACTAACcttacgtcttcatctgaaaagacgcaact t" /listShort="sspK" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(928333) /Source="Nicolas_upshifts" /id="U652" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=867 /SigmaFactorBS="ttcatgtgtgcagtctcctttcttcaggaaaaaaataaCGCT TTAttacgtggtgttctCCATATACTAACcttacgtcttcatctgaaaagacgcaact t" /listShort="sspK" /GFF_Attribute="listLong" promotor_-35 complement(928349..928355) /Source="Nicolas_upshift_promotors" /id="U652" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=867 /SigmaFactorBS="ttcatgtgtgcagtctcctttcttcaggaaaaaaataaCGCT TTAttacgtggtgttctCCATATACTAACcttacgtcttcatctgaaaagacgcaact t" /listShort="sspK" /GFF_Attribute="listLong" /label="promotor_-35" CDS 928389..928658 /gene="yfhJ" /locus_tag="BSU_08560" /old_locus_tag="BSU08560" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_388736.1" /db_xref="EnsemblGenomes-Gn:BSU08560" /db_xref="EnsemblGenomes-Tr:CAB12684" /db_xref="InterPro:IPR026952" /db_xref="SubtiList:BG12885" /db_xref="UniProtKB/Swiss-Prot:O31578" /translation="MNMYIEKLTNLLLEKNEMISYIQAKTWVELLWSDFEATYAKAGH AYQGEKMTEKIVTQWIENYGGQLHLFQSSRNDVNDYLNQSRGLLH*" gene 928389..928658 /gene="yfhJ" /locus_tag="BSU_08560" /old_locus_tag="BSU08560" downshifts 928647 /Source="Nicolas_upshifts" /id="D426" /incds=0 /nref=62 /ntot=233 /MaxReadThrough="2.9538" /MaxDrop="5.3621" /score="19.3423239" /energy="-10.6" /TU="NA" /idTUdmin="U650" /TUdmin=0 /isTUend="TRUE" promotor_-35 928736..928742 /Source="Nicolas_upshift_promotors" /id="U653" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=223 /SigmaFactorBS="ttaaaattaccttaacaggaagaaatcataaacaaaacaTGT TTCAccagcctgtcaatcaGGGAATACCACTTATATCTtgtcaaaatgcgaggaggag c" /listShort="yfhK, S292, yfhL, yfhM, S293, S294, csbB, S295, yfhO" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 928757 /Source="Nicolas_upshifts" /id="U653" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=223 /SigmaFactorBS="ttaaaattaccttaacaggaagaaatcataaacaaaacaTGT TTCAccagcctgtcaatcaGGGAATACCACTTATATCTtgtcaaaatgcgaggaggag c" /listShort="yfhK, S292, yfhL, yfhM, S293, S294, csbB, S295, yfhO" /GFF_Attribute="listLong" promotor_-10 928758..928776 /Source="Nicolas_upshift_promotors" /id="U653" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=223 /SigmaFactorBS="ttaaaattaccttaacaggaagaaatcataaacaaaacaTGT TTCAccagcctgtcaatcaGGGAATACCACTTATATCTtgtcaaaatgcgaggaggag c" /listShort="yfhK, S292, yfhL, yfhM, S293, S294, csbB, S295, yfhO" /GFF_Attribute="listLong" /label="promotor_-10" CDS 928803..929321 /gene="yfhK" /locus_tag="BSU_08570" /old_locus_tag="BSU08570" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative exported protein" /protein_id="NP_388737.1" /db_xref="EnsemblGenomes-Gn:BSU08570" /db_xref="EnsemblGenomes-Tr:CAB12685" /db_xref="InterPro:IPR003646" /db_xref="SubtiList:BG12886" /db_xref="UniProtKB/Swiss-Prot:O31579" /translation="MKKKQVMLALTAAAGLGLTALHSAPAAKAAPLHDISVSMPSSDT YIIKAGKLNVRTEPNHEGDILGTVSSEQKVKVDRFVNADWAQIHFKGKKAYISTHFLM KTASQAKTTKQTAFYTPTPENGKAKQLSSGTEVTILGWGFSENGGFDFTWAFVDYGGV KGYIHTKDLQMR*" gene 928803..929321 /gene="yfhK" /locus_tag="BSU_08570" /old_locus_tag="BSU08570" S_feature 929322..929389 /Source="Nicolas_S_feature" /locus_tag="new_929322_929389" /HighExp="Etha, Sw, Salt, M9-stat, B60, B36, Gly, LoTm, BC, LPhT" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigB" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S292" promotor_-35 929357..929366 /Source="Nicolas_upshift_promotors" /id="U654" /multdbtbs="SigW" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1692 /SigmaFactorBS="ccgaggcttgtctttttgcctatgcaTGAAACATTTcttctt tctgcACGTAACAATGAGAAAggagatgatgatatgacgggtttagtcggcggagggc t" /listShort="yfhL, yfhM" /listLong="S293, S294, csbB, S295, yfhO" /label="promotor_-35" promotor_-10 929378..929393 /Source="Nicolas_upshift_promotors" /id="U654" /multdbtbs="SigW" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1692 /SigmaFactorBS="ccgaggcttgtctttttgcctatgcaTGAAACATTTcttctt tctgcACGTAACAATGAGAAAggagatgatgatatgacgggtttagtcggcggagggc t" /listShort="yfhL, yfhM" /listLong="S293, S294, csbB, S295, yfhO" /label="promotor_-10" upshifts 929391 /Source="Nicolas_upshifts" /id="U654" /multdbtbs="SigW" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1692 /SigmaFactorBS="ccgaggcttgtctttttgcctatgcaTGAAACATTTcttctt tctgcACGTAACAATGAGAAAggagatgatgatatgacgggtttagtcggcggagggc t" /listShort="yfhL, yfhM" /listLong="S293, S294, csbB, S295, yfhO" CDS 929406..929738 /gene="spdL" /locus_tag="BSU_08580" /old_locus_tag="BSU08580" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:16629676, 22720735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16629676, 22720735; Product type f: factor" /codon_start=1 /transl_table=11 /product="factor for peptide SdpC immunity" /protein_id="NP_388738.1" /db_xref="EnsemblGenomes-Gn:BSU08580" /db_xref="EnsemblGenomes-Tr:CAB12686" /db_xref="GOA:O31580" /db_xref="InterPro:IPR025962" /db_xref="SubtiList:BG12887" /db_xref="UniProtKB/Swiss-Prot:O31580" /translation="MTGLVGGGLMIIAGILIKLFPPKSINSVYGYRTRRSMSDQRLWN EANRYSASLMILSGLVIAGMGLLLGSNLFILQLILLIAACVITFMLTEKRLKIMTHSQ GGDRSGRS*" gene 929406..929738 /gene="spdL" /locus_tag="BSU_08580" /old_locus_tag="BSU08580" CDS 929725..930585 /gene="ephM" /locus_tag="BSU_08590" /old_locus_tag="BSU08590" /EC_number="3.3.2.10" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:16597997, 20941576" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16597997, 20941576; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="stress induced epoxide hydrolase" /protein_id="NP_388739.1" /db_xref="EnsemblGenomes-Gn:BSU08590" /db_xref="EnsemblGenomes-Tr:CAB12687" /db_xref="GOA:O31581" /db_xref="InterPro:IPR000073" /db_xref="InterPro:IPR000639" /db_xref="InterPro:IPR029058" /db_xref="SubtiList:BG12888" /db_xref="UniProtKB/Swiss-Prot:O31581" /translation="MDGVKCQFVNTNGITLHVAAAGREDGPLIVLLHGFPEFWYGWKN QIKPLVDAGYRVIAPDQRGYNLSDKPEGIDSYRIDTLRDDIIGLITQFTDEKAIVIGH DWGGAVAWHLASTRPEYLEKLIAINIPHPHVMKTVTPLYPPQWLKSSYIAYFQLPDIP EASLRENDYDTLDKAIGLSDRPALFTSEDVSRYKEAWKQPGALTAMLNWYRALRKGSL AEKPSYETVPYRMIWGMEDRFLSRKLAKETERHCPNGHLIFVDEASHWINHEKPAIVN QLILEYLKNQ*" gene 929725..930585 /gene="ephM" /locus_tag="BSU_08590" /old_locus_tag="BSU08590" downshifts 930583 /Source="Nicolas_upshifts" /id="D427" /incds=0 /nref=27 /ntot=191 /MaxReadThrough="5.0793" /MaxDrop="4.1326" /score="3.7712168" /energy="-8.4" /TU="U653,U654" /idTUdmin="U654" /TUdmin="-132" /isTUend="FALSE" promotor_-35 930643..930649 /Source="Nicolas_upshift_promotors" /id="U655" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.99000999000999" /psig="0.99000999000999" /xcortree=945 /SigmaFactorBS="tcataatggcagactttttctgtgcgttttttTTCATAGtct gttttaaacaTGACAAAATAACattaaaaatcatgaatgtcaccataaaattgtaaca a" /listShort="S293, S294, csbB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 930663..930674 /Source="Nicolas_upshift_promotors" /id="U655" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.99000999000999" /psig="0.99000999000999" /xcortree=945 /SigmaFactorBS="tcataatggcagactttttctgtgcgttttttTTCATAGtct gttttaaacaTGACAAAATAACattaaaaatcatgaatgtcaccataaaattgtaaca a" /listShort="S293, S294, csbB" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 930671..930735 /Source="Nicolas_S_feature" /locus_tag="new_930671_930735" /HighExp="Etha, S5, M9-stat, T0.30H, Sw, T-0.40H, B60, S8, B36, T1.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigGF, SigB" /TUshortPSig="0.99, 1" /TUlongSig="SigWXY" /TUlongPSig=1 /label="S293" upshifts 930671 /Source="Nicolas_upshifts" /id="U655" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.99000999000999" /psig="0.99000999000999" /xcortree=945 /SigmaFactorBS="tcataatggcagactttttctgtgcgttttttTTCATAGtct gttttaaacaTGACAAAATAACattaaaaatcatgaatgtcaccataaaattgtaaca a" /listShort="S293, S294, csbB" /GFF_Attribute="listLong" promotor_-10 complement(930693..930712) /Source="Nicolas_upshift_promotors" /id="U656" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.446553446553447" /psig="0.97902097902098" /xcortree=2407 /SigmaFactorBS="caaatcttcagtaaggctattcctttttttaaagtCGtttaa acctgtttTTTGTTACAATTTTATGGTGacattcatgatttttaatgttattttgtca t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(930702) /Source="Nicolas_upshifts" /id="U656" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.446553446553447" /psig="0.97902097902098" /xcortree=2407 /SigmaFactorBS="caaatcttcagtaaggctattcctttttttaaagtCGtttaa acctgtttTTTGTTACAATTTTATGGTGacattcatgatttttaatgttattttgtca t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 930718..930724 /Source="Nicolas_upshift_promotors" /id="U657" /multdbtbs="SigB,SigX" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=124 /SigmaFactorBS="taaaaatcatgaatgtcaccataaaattgtaacaaaaaacaG GTTTAAacgactttaaaaaaAGGAATAGCCTTACTGAAGatttgtgtaaaactcccct a" /listShort="S294, csbB, S295, yfhO" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 complement(930726..930727) /Source="Nicolas_upshift_promotors" /id="U656" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.446553446553447" /psig="0.97902097902098" /xcortree=2407 /SigmaFactorBS="caaatcttcagtaaggctattcctttttttaaagtCGtttaa acctgtttTTTGTTACAATTTTATGGTGacattcatgatttttaatgttattttgtca t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" S_feature 930737..930817 /Source="Nicolas_S_feature" /locus_tag="new_930737_930817" /HighExp="M9-stat, LBGexp, Lbexp, T0.30H, dia0, T1.30H, T1.0H, LBGtran, Paraq, T2.30H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigB, SigGF, SigB" /TUshortPSig="1, 0.99, 1" /TUlongSig="SigWXY" /TUlongPSig=1 /label="S294" upshifts 930737 /Source="Nicolas_upshifts" /id="U657" /multdbtbs="SigB,SigX" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=124 /SigmaFactorBS="taaaaatcatgaatgtcaccataaaattgtaacaaaaaacaG GTTTAAacgactttaaaaaaAGGAATAGCCTTACTGAAGatttgtgtaaaactcccct a" /listShort="S294, csbB, S295, yfhO" /GFF_Attribute="listLong" promotor_-10 930739..930757 /Source="Nicolas_upshift_promotors" /id="U657" /multdbtbs="SigB,SigX" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=124 /SigmaFactorBS="taaaaatcatgaatgtcaccataaaattgtaacaaaaaacaG GTTTAAacgactttaaaaaaAGGAATAGCCTTACTGAAGatttgtgtaaaactcccct a" /listShort="S294, csbB, S295, yfhO" /GFF_Attribute="listLong" /label="promotor_-10" CDS 930818..931807 /gene="csbB" /locus_tag="BSU_08600" /old_locus_tag="BSU08600" /EC_number="2.4.-.-" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 8921856, 9636707, 23632331; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative bactoprenol glycosyl transferase, phageorigin" /protein_id="NP_388740.1" /db_xref="EnsemblGenomes-Gn:BSU08600" /db_xref="EnsemblGenomes-Tr:CAB12688" /db_xref="GOA:Q45539" /db_xref="InterPro:IPR001173" /db_xref="InterPro:IPR029044" /db_xref="SubtiList:BG11834" /db_xref="UniProtKB/Swiss-Prot:Q45539" /translation="MKQGLISIIIPSYNEGYNVKLIHESLKKEFKNIHYDYEIFFIND GSVDDTLQQIKDLAATCSRVKYISFSRNFGKEAAILAGFEHVQGEAVIVMDADLQHPT YLLKEFIKGYEEGYDQVIAQRNRKGDSFVRSLLSSMYYKFINKAVEVDLRDGVGDFRL LSRQAVNALLKLSEGNRFSKGLFCWIGFDQKIVFYENVERKNGTSKWSFSSLFNYGMD GVVSFNHKPLRLCFYTGIFILLLSIIYIIATFVKILTNGISVPGYFTIISAVLFLGGV QLLSLGIIGEYIGRIYYETKKRPHYLIKEANIPNKDLPETNELKSMRRLTKMH*" gene 930818..931807 /gene="csbB" /locus_tag="BSU_08600" /old_locus_tag="BSU08600" upshifts complement(930967) /Source="Nicolas_upshifts" /id="U658" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.712287712287712" /psig="0.037962037962038" /xcortree=125 /SigmaFactorBS="agaaaaagatatatattttacccggctgcaCGTCGctgccaa gtctttgatCTGCTgaagcgtgtcatcaacacttccgtcgtttatgaagaatatttca t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 complement(930972..930976) /Source="Nicolas_upshift_promotors" /id="U658" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.712287712287712" /psig="0.037962037962038" /xcortree=125 /SigmaFactorBS="agaaaaagatatatattttacccggctgcaCGTCGctgccaa gtctttgatCTGCTgaagcgtgtcatcaacacttccgtcgtttatgaagaatatttca t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 complement(930993..930997) /Source="Nicolas_upshift_promotors" /id="U658" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.712287712287712" /psig="0.037962037962038" /xcortree=125 /SigmaFactorBS="agaaaaagatatatattttacccggctgcaCGTCGctgccaa gtctttgatCTGCTgaagcgtgtcatcaacacttccgtcgtttatgaagaatatttca t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" S_feature 931808..931878 /Source="Nicolas_S_feature" /locus_tag="new_931808_931878" /HighExp="LPhT, Heat, Etha, LBGexp, M9-stat, LBGtran, Lbexp, Sw, dia0, Oxctl" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigB, SigB" /TUshortPSig="1, 1" /TUlongSig="SigWXY" /TUlongPSig=1 /label="S295" CDS 931879..934464 /gene="yfhO" /locus_tag="BSU_08610" /old_locus_tag="BSU08610" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 23632331; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="conserved membrane protein" /protein_id="NP_388741.2" /db_xref="EnsemblGenomes-Gn:BSU08610" /db_xref="EnsemblGenomes-Tr:CAB12689" /db_xref="GOA:O31582" /db_xref="InterPro:IPR018580" /db_xref="SubtiList:BG12889" /db_xref="UniProtKB/Swiss-Prot:O31582" /translation="MKRKHIMIYAASLLVSVLAHAFFVKEWAEGRYMTGPGDGLAQMI VFKKLLFDQYTHGNFFYNYSFGLGGGTFSQLGYYFSASFLFLAVSAAVWLLQAVQLIG ETDTLFWAESAVFISIFKLSLIIFTSASVFHYLLKHRAASFTGAVLYGVSIIYFRHEA YWEFFTDTMVWLPLLVLGAEKIIRERRPAWFIVACSLTLINNFYFAYINLIFIGIYVL FRWLIRLEPHEEKRWIQIRLFLVSGFISFGISAAAFVPVVYGFLNNLRPPYSQKIEWL NFDDNILFSSRIIIVPAAFLLFLFIISFYKNRVFRLFAGLSLLFILFHFSPYAASVFN GFSAPQNRFEYVLAFTIAGAAAAGLSQLSELKRKELLPAAAVVLLLYLYHIQRYKLDI WKPANESILLLLLMTIAALFAAAFAKKRAKMAVYGIIILSSLFVANSYQKYALSEGGD LDSVTKEYLTSEEYRGRESSELIRRLQKEDDDPLMRIDWMNGVRNNTPIIYGFNGFSA YSSILNKDLLAFYWNDLSIDMGRESVSRYASLGDRANLYSLLYGKYYMTEKTNEASVP YGFKKHLETEHYAVYENQYMLPFVKTADAIYSESELDRLPALAKEQAMLKGIILKDPS GKTEQTPKPSNLITKSDITAKQAQYQNGLLTVTGENGGELIITPKQPSSAPGDYYVSF YLKSKAKDKGFTLKVNDYVTTRKSNKSIYKTGVNNITVRVPKSGHISINLPKGTYELR NIALYEENYQTLKNAVMQNKTEKADKLNWNKNRLTFSYHLSKDQYIMLPIPYEKGWEL KINGKTQKIEKADYAFIGFKAQKGDNHIELTYYPPYFKISAIISLVSLLLAVFYIRRK KPGSI*" gene 931879..934464 /gene="yfhO" /locus_tag="BSU_08610" /old_locus_tag="BSU08610" downshifts 934433 /Source="Nicolas_upshifts" /id="D428" /incds=0 /nref=63 /ntot=217 /MaxReadThrough="2.13267" /MaxDrop="4.17784" /score="2.41489488" /energy="-13.3" /TU="NA" /idTUdmin="U657" /TUdmin="-1" /isTUend="TRUE" CDS complement(934457..935440) /gene="yfhP" /locus_tag="BSU_08620" /old_locus_tag="BSU08620" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 10463184, 10524235, 15849754, 16850406, 24237659; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative membrane hydrolase" /protein_id="NP_388742.1" /db_xref="EnsemblGenomes-Gn:BSU08620" /db_xref="EnsemblGenomes-Tr:CAB12690" /db_xref="GOA:O31583" /db_xref="InterPro:IPR007404" /db_xref="SubtiList:BG12890" /db_xref="UniProtKB/Swiss-Prot:O31583" /translation="MDTGTHVVMGIALGGIATLDPVVGSDPAMAHAVMIATLAGSQAP DIDTVLKLKNNAVYIRNHRGFTHSIPAVLFWSVIIPAILYLFYPQADFLHLWLWTLLA VVLHVFVDIFNAYGTQAIRPFSKKWVALGLINTFDPFIFISHLAAIAIWYAGGSPGIT FLSLYIILVGYYLVRLIMQLRIKRKLHEMIHDEIESIIISPTMKFRQWRIAVTTAHAF YVGRSMEGHVVILDTFNRVPVPETDVMHAAKQDDNIAAFLSFSPVYRWEVDTFKDHYE VRFIDLRYRSKGHYPFVAIVHIGHDLTIRSSYTGWIFSEEKLQKKLKLGSI*" gene complement(934457..935440) /gene="yfhP" /locus_tag="BSU_08620" /old_locus_tag="BSU08620" downshifts complement(934491) /Source="Nicolas_upshifts" /id="D429" /incds=0 /nref=28 /ntot=200 /MaxReadThrough="2.65266" /MaxDrop="4.43244" /score="25.5564412" /energy="-17.5" /TU="NA" /idTUdmin="U661" /TUdmin="-3" /isTUend="TRUE" promotor_-35 934914..934923 /Source="Nicolas_upshift_promotors" /id="U659" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1381 /SigmaFactorBS="atgaagcttccgtttaattctcagctgcatgatcAGGCGCAC CAagtagtagcctaCCAATATGATATATAAGCTGagaaacgtgatgccgggactcccg c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 934936..934955 /Source="Nicolas_upshift_promotors" /id="U659" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1381 /SigmaFactorBS="atgaagcttccgtttaattctcagctgcatgatcAGGCGCAC CAagtagtagcctaCCAATATGATATATAAGCTGagaaacgtgatgccgggactcccg c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 934940 /Source="Nicolas_upshifts" /id="U659" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1381 /SigmaFactorBS="atgaagcttccgtttaattctcagctgcatgatcAGGCGCAC CAagtagtagcctaCCAATATGATATATAAGCTGagaaacgtgatgccgggactcccg c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" S_feature complement(935441..935588) /Source="Nicolas_S_feature" /locus_tag="new_935441_935588_c" /HighExp="Diami, dia15, M9-stat, dia5, Etha, H2O2, S6, Salt, Lbtran, LBGstat" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.997" /TUlongSig="NA" /TUlongPSig="NA" /label="S296" promotor_-35 935545..935549 /Source="Nicolas_upshift_promotors" /id="U660" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.718281718281718" /psig="0.998001998001998" /xcortree=2674 /SigmaFactorBS="tttaaactgattcaatcgttctcatatgtttccGCTTTttct ttattactattTAATGTAACATATTATCGTActgtgcccttagtgtacaacaaaaaac a" /listShort="S297, yfhQ, S298, fabL, sspE" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 935565..935584 /Source="Nicolas_upshift_promotors" /id="U660" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.718281718281718" /psig="0.998001998001998" /xcortree=2674 /SigmaFactorBS="tttaaactgattcaatcgttctcatatgtttccGCTTTttct ttattactattTAATGTAACATATTATCGTActgtgcccttagtgtacaacaaaaaac a" /listShort="S297, yfhQ, S298, fabL, sspE" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 935572 /Source="Nicolas_upshifts" /id="U660" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.718281718281718" /psig="0.998001998001998" /xcortree=2674 /SigmaFactorBS="tttaaactgattcaatcgttctcatatgtttccGCTTTttct ttattactattTAATGTAACATATTATCGTActgtgcccttagtgtacaacaaaaaac a" /listShort="S297, yfhQ, S298, fabL, sspE" /GFF_Attribute="listLong" S_feature 935578..935655 /Source="Nicolas_S_feature" /locus_tag="new_935578_935655" /HighExp="H2O2, G150, G180, LBGstat, dia15, Diami, Oxctl, Paraq, G135, dia0" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.998" /TUlongSig="NA" /TUlongPSig="NA" /label="S297" promotor_-10 complement(935586..935605) /Source="Nicolas_upshift_promotors" /id="U661" /multdbtbs="SigK,SigK" /comp="M19" /sig="SigA" /pcomp="0.875124875124875" /psig="0.997002997002997" /xcortree=643 /SigmaFactorBS="tctccccagtctttcgcgcccCGCTTTTCtttagactgtttt tTGTTGTACACTAAGGGCACAgtacgataatatgttacattaaatagtaataaagaaa a" /listShort="S296, yfhP" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(935588) /Source="Nicolas_upshifts" /id="U661" /multdbtbs="SigK,SigK" /comp="M19" /sig="SigA" /pcomp="0.875124875124875" /psig="0.997002997002997" /xcortree=643 /SigmaFactorBS="tctccccagtctttcgcgcccCGCTTTTCtttagactgtttt tTGTTGTACACTAAGGGCACAgtacgataatatgttacattaaatagtaataaagaaa a" /listShort="S296, yfhP" /GFF_Attribute="listLong" promotor_-35 complement(935620..935627) /Source="Nicolas_upshift_promotors" /id="U661" /multdbtbs="SigK,SigK" /comp="M19" /sig="SigA" /pcomp="0.875124875124875" /psig="0.997002997002997" /xcortree=643 /SigmaFactorBS="tctccccagtctttcgcgcccCGCTTTTCtttagactgtttt tTGTTGTACACTAAGGGCACAgtacgataatatgttacattaaatagtaataaagaaa a" /listShort="S296, yfhP" /GFF_Attribute="listLong" /label="promotor_-35" CDS 935656..936765 /gene="mutY" /locus_tag="BSU_08630" /old_locus_tag="BSU08630" /EC_number="3.2.2.-" /function="16.8: Protect" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:10463184, 20971907, 21954439, 27399782" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10463184, 20971907, 21954439, 27399782; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="A/G-specific adenine glycosylase or DNA-(apurinic or apyrimidinic site) lyase" /protein_id="NP_388743.1" /db_xref="EnsemblGenomes-Gn:BSU08630" /db_xref="EnsemblGenomes-Tr:CAB12691" /db_xref="GOA:O31584" /db_xref="InterPro:IPR003265" /db_xref="InterPro:IPR003651" /db_xref="InterPro:IPR005760" /db_xref="InterPro:IPR011257" /db_xref="InterPro:IPR015797" /db_xref="InterPro:IPR023170" /db_xref="InterPro:IPR029119" /db_xref="SubtiList:BG12891" /db_xref="UniProtKB/Swiss-Prot:O31584" /translation="MNVLEDKLKQKDIQQFRDDLISWFEREQRVLPWREDQDPYKVWV SEVMLQQTRVETVIPYFLRFVEQFPTVEALADADEEKVLKAWEGLGYYSRVRNLQSAV KEVKQEYGGIVPPDEKDFGGLKGVGPYTKGAVLSIAYNKPIPAVDGNVMRVMSRILSI WDDIAKPKTRTIFEDAIRAFISKEKPSEFNQGLMELGALICTPKSPSCLLCPVQQHCS AFEEGTERELPVKSKKKKPGIKTMAAIVLTDEDGQVYIHKRPSKGLLANLWEFPNLET QKGIKTEREQLIAFLENEYGIQADISDLQGVVEHVFTHLVWNISVFFGKVKQVSDTSK LKKVTKEELEQFAFPVSHQKIWKMAGEAAAISAAP*" gene 935656..936765 /gene="mutY" /locus_tag="BSU_08630" /old_locus_tag="BSU08630" promotor_-35 936602..936606 /Source="Nicolas_upshift_promotors" /id="U662" /multdbtbs="SigA" /comp="M16" /sig="SigA" /pcomp="0.556443556443556" /psig="0.997002997002997" /xcortree=2563 /SigmaFactorBS="gtagtcgagcatgttttcacccacctggTATGGaatatttca gtgtttTTCGGTAAAGTAAAACAAGTgtcggataccagcaagctgaaaaaagtaacga a" /listShort="S298, fabL, sspE" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 936622..936641 /Source="Nicolas_upshift_promotors" /id="U662" /multdbtbs="SigA" /comp="M16" /sig="SigA" /pcomp="0.556443556443556" /psig="0.997002997002997" /xcortree=2563 /SigmaFactorBS="gtagtcgagcatgttttcacccacctggTATGGaatatttca gtgtttTTCGGTAAAGTAAAACAAGTgtcggataccagcaagctgaaaaaagtaacga a" /listShort="S298, fabL, sspE" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 936634 /Source="Nicolas_upshifts" /id="U662" /multdbtbs="SigA" /comp="M16" /sig="SigA" /pcomp="0.556443556443556" /psig="0.997002997002997" /xcortree=2563 /SigmaFactorBS="gtagtcgagcatgttttcacccacctggTATGGaatatttca gtgtttTTCGGTAAAGTAAAACAAGTgtcggataccagcaagctgaaaaaagtaacga a" /listShort="S298, fabL, sspE" /GFF_Attribute="listLong" S_feature 936766..937078 /Source="Nicolas_S_feature" /locus_tag="new_936766_937078" /HighExp="H2O2, G150, dia15, G135, G180, Oxctl, Paraq, dia0, LBGexp, Lbexp" /AntisenseName="yfhS" /AntisenseCor="-0.72611377663365595" /AntisenseRegPval="-44.6" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="0.997, 0.998" /TUlongSig="NA" /TUlongPSig="NA" /label="S298" CDS complement(936773..936997) /gene="yfhS" /locus_tag="BSU_08640" /old_locus_tag="BSU08640" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 10463184" /codon_start=1 /transl_table=11 /product="conserved protein related to sporulation" /protein_id="NP_388744.1" /db_xref="EnsemblGenomes-Gn:BSU08640" /db_xref="EnsemblGenomes-Tr:CAB12692" /db_xref="SubtiList:BG12892" /db_xref="UniProtKB/Swiss-Prot:O31585" /translation="MYVGRDMSELNMVSKKDWKNSELAYFHHAFQQIMPYLNEEGQSK YRELTQEIEARGGMKRNEADYSHGTRVSYD*" gene complement(936773..936997) /gene="yfhS" /locus_tag="BSU_08640" /old_locus_tag="BSU08640" promotor_-10 complement(937027..937038) /Source="Nicolas_upshift_promotors" /id="U663" /multdbtbs="SigE" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=858 /SigmaFactorBS="ttttgttccatttttcctcatctccttgtagCGTATAGttct tttatttccACAAACAATAATggcaagaactttaaagggggtcttctgttatgtatgt c" /listShort="yfhS" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(937029) /Source="Nicolas_upshifts" /id="U663" /multdbtbs="SigE" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=858 /SigmaFactorBS="ttttgttccatttttcctcatctccttgtagCGTATAGttct tttatttccACAAACAATAATggcaagaactttaaagggggtcttctgttatgtatgt c" /listShort="yfhS" /GFF_Attribute="listLong" promotor_-35 complement(937052..937058) /Source="Nicolas_upshift_promotors" /id="U663" /multdbtbs="SigE" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=858 /SigmaFactorBS="ttttgttccatttttcctcatctccttgtagCGTATAGttct tttatttccACAAACAATAATggcaagaactttaaagggggtcttctgttatgtatgt c" /listShort="yfhS" /GFF_Attribute="listLong" /label="promotor_-35" CDS 937079..937831 /gene="fabL" /locus_tag="BSU_08650" /old_locus_tag="BSU08650" /EC_number="1.3.1.10" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:11007778, 12440970, 17329825, 21185310" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11007778, 12440970, 17329825, 21185310; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="enoyl-acyl carrier protein reductase III" /protein_id="NP_388745.1" /db_xref="EnsemblGenomes-Gn:BSU08650" /db_xref="EnsemblGenomes-Tr:CAB12693" /db_xref="GOA:P71079" /db_xref="InterPro:IPR002347" /db_xref="InterPro:IPR036291" /db_xref="PDB:3OIC" /db_xref="PDB:3OID" /db_xref="SubtiList:BG12221" /db_xref="UniProtKB/Swiss-Prot:P71079" /translation="MEQNKCALVTGSSRGVGKAAAIRLAENGYNIVINYARSKKAALE TAEEIEKLGVKVLVVKANVGQPAKIKEMFQQIDETFGRLDVFVNNAASGVLRPVMELE ETHWDWTMNINAKALLFCAQEAAKLMEKNGGGHIVSISSLGSIRYLENYTTVGVSKAA LEALTRYLAVELSPKQIIVNAVSGGAIDTDALKHFPNREDLLEDARQNTPAGRMVEIK DMVDTVEFLVSSKADMIRGQTIIVDGGRSLLV*" gene 937079..937831 /gene="fabL" /locus_tag="BSU_08650" /old_locus_tag="BSU08650" promotor_-35 937848..937854 /Source="Nicolas_upshift_promotors" /id="U664" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp="0.988011988011988" /psig="0.988011988011988" /xcortree=800 /SigmaFactorBS="cggacgctcactgctcgtttaaaaatttttaaaaaagaGGAA TAGctatacgatcacctGCACATTCTAATgaccgtggaggtgataacaatggctaact c" /listShort="sspE" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 937869..937880 /Source="Nicolas_upshift_promotors" /id="U664" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp="0.988011988011988" /psig="0.988011988011988" /xcortree=800 /SigmaFactorBS="cggacgctcactgctcgtttaaaaatttttaaaaaagaGGAA TAGctatacgatcacctGCACATTCTAATgaccgtggaggtgataacaatggctaact c" /listShort="sspE" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 937870 /Source="Nicolas_upshifts" /id="U664" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp="0.988011988011988" /psig="0.988011988011988" /xcortree=800 /SigmaFactorBS="cggacgctcactgctcgtttaaaaatttttaaaaaagaGGAA TAGctatacgatcacctGCACATTCTAATgaccgtggaggtgataacaatggctaact c" /listShort="sspE" /GFF_Attribute="listLong" promotor_-10 complement(937877..937891) /Source="Nicolas_upshift_promotors" /id="U665" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.841158841158841" /psig="0.022977022977023" /xcortree=711 /SigmaFactorBS="tggttttgttttctaacttgttgagcgtttgttttgctgaag ttatttgagttaGCCATtgttatcaCCTCCACGGTCATTAgaatgtgcaggtgatcgt a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(937898) /Source="Nicolas_upshifts" /id="U665" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.841158841158841" /psig="0.022977022977023" /xcortree=711 /SigmaFactorBS="tggttttgttttctaacttgttgagcgtttgttttgctgaag ttatttgagttaGCCATtgttatcaCCTCCACGGTCATTAgaatgtgcaggtgatcgt a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(937900..937904) /Source="Nicolas_upshift_promotors" /id="U665" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.841158841158841" /psig="0.022977022977023" /xcortree=711 /SigmaFactorBS="tggttttgttttctaacttgttgagcgtttgttttgctgaag ttatttgagttaGCCATtgttatcaCCTCCACGGTCATTAgaatgtgcaggtgatcgt a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" CDS 937900..938154 /gene="sspE" /locus_tag="BSU_08660" /old_locus_tag="BSU08660" /function="16.8: Protect" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:1744043, 7592342, 9540829, 19542328, 23314362" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1744043, 7592342, 9540829, 19542328, 23314362; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="small acid-soluble spore protein (gamma-type SASP)" /protein_id="NP_388746.1" /db_xref="EnsemblGenomes-Gn:BSU08660" /db_xref="EnsemblGenomes-Tr:CAB12694" /db_xref="GOA:P07784" /db_xref="InterPro:IPR006341" /db_xref="SubtiList:BG10789" /db_xref="UniProtKB/Swiss-Prot:P07784" /translation="MANSNNFSKTNAQQVRKQNQQSAAGQGQFGTEFASETNAQQVRK QNQQSAGQQGQFGTEFASETDAQQVRQQNQSAEQNKQQNS*" gene 937900..938154 /gene="sspE" /locus_tag="BSU_08660" /old_locus_tag="BSU08660" downshifts 938152 /Source="Nicolas_upshifts" /id="D430" /incds=0 /nref=261 /ntot=269 /MaxReadThrough="1.59207" /MaxDrop="8.74804" /score="9.25353719" /energy="-9.5" /TU="NA" /idTUdmin="U660" /TUdmin=0 /isTUend="TRUE" downshifts complement(938177) /Source="Nicolas_upshifts" /id="D431" /incds=0 /nref=3 /ntot=21 /MaxReadThrough="1.21036" /MaxDrop="5.14076" /score="-9.78320441" /energy="-7.1" /TU="NA" /idTUdmin="U663" /TUdmin="-1687" /isTUend="FALSE" CDS 938243..938587 /gene="ygaB" /locus_tag="BSU_08670" /old_locus_tag="BSU08670" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_388747.1" /db_xref="EnsemblGenomes-Gn:BSU08670" /db_xref="EnsemblGenomes-Tr:CAB12695" /db_xref="InterPro:IPR025572" /db_xref="SubtiList:BG12222" /db_xref="UniProtKB/Swiss-Prot:P71080" /translation="MSQRVCFMEIEMIKGGNVYTFIRLKEEPMTEFEKLVSEQMKTMD KLLDLQSELDRCKQIEAELRHLERDARLRGIQAEIAVKRKHLADIQDMFQKQTEQVIR SYRSSEKPSSFV*" gene 938243..938587 /gene="ygaB" /locus_tag="BSU_08670" /old_locus_tag="BSU08670" promotor_-35 938250..938258 /Source="Nicolas_upshift_promotors" /id="U666" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp=1 /psig=1 /xcortree=444 /SigmaFactorBS="aaaaacgacaaaacttgtggaaggtctacagaatgagtcAAA GGGTTTgctttatggaGATCGAAATGATTAAAGGAggaaatgtttatactttcatcag g" /listShort="ygaB, S299, ygaC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 938269..938287 /Source="Nicolas_upshift_promotors" /id="U666" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp=1 /psig=1 /xcortree=444 /SigmaFactorBS="aaaaacgacaaaacttgtggaaggtctacagaatgagtcAAA GGGTTTgctttatggaGATCGAAATGATTAAAGGAggaaatgtttatactttcatcag g" /listShort="ygaB, S299, ygaC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 938271 /Source="Nicolas_upshifts" /id="U666" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp=1 /psig=1 /xcortree=444 /SigmaFactorBS="aaaaacgacaaaacttgtggaaggtctacagaatgagtcAAA GGGTTTgctttatggaGATCGAAATGATTAAAGGAggaaatgtttatactttcatcag g" /listShort="ygaB, S299, ygaC" /GFF_Attribute="listLong" downshifts 938570 /Source="Nicolas_upshifts" /id="D432" /incds=0 /nref=1 /ntot=27 /MaxReadThrough="4.84572" /MaxDrop="3.29993" /score="13.9694142" /energy="-11.5" /TU="U666" /idTUdmin="U660" /TUdmin=418 /isTUend="FALSE" promotor_-35 938626..938633 /Source="Nicolas_upshift_promotors" /id="U667" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.641358641358641" /psig=1 /xcortree=2074 /SigmaFactorBS="tgtgccattccccggccggaatggctctttTATTTTCAtttt tcaatttgtAACGTTATAATAGGTAAAAGacgttgtcggtaagcaaatttggacatac t" /listShort="S299, ygaC, ygaD" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 938647..938666 /Source="Nicolas_upshift_promotors" /id="U667" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.641358641358641" /psig=1 /xcortree=2074 /SigmaFactorBS="tgtgccattccccggccggaatggctctttTATTTTCAtttt tcaatttgtAACGTTATAATAGGTAAAAGacgttgtcggtaagcaaatttggacatac t" /listShort="S299, ygaC, ygaD" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 938656..938730 /Source="Nicolas_S_feature" /locus_tag="new_938656_938730" /HighExp="Etha, dia15, dia5, Diami, Salt, H2O2, BC, T5.0H, Cold, C90" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigH" /TUshortPSig="1, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S299" upshifts 938656 /Source="Nicolas_upshifts" /id="U667" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.641358641358641" /psig=1 /xcortree=2074 /SigmaFactorBS="tgtgccattccccggccggaatggctctttTATTTTCAtttt tcaatttgtAACGTTATAATAGGTAAAAGacgttgtcggtaagcaaatttggacatac t" /listShort="S299, ygaC, ygaD" /GFF_Attribute="listLong" CDS 938731..939261 /gene="ygaC" /locus_tag="BSU_08680" /old_locus_tag="BSU08680" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 19383706, 22333191; Product type f: factor" /codon_start=1 /transl_table=11 /product="putative RNA binding factor" /protein_id="NP_388748.3" /db_xref="EnsemblGenomes-Gn:BSU08680" /db_xref="EnsemblGenomes-Tr:CAB12696" /db_xref="InterPro:IPR007295" /db_xref="InterPro:IPR016882" /db_xref="InterPro:IPR035930" /db_xref="SubtiList:BG12223" /db_xref="UniProtKB/Swiss-Prot:Q796Z1" /translation="MGYPKEGETIQIHSYKHNGLIHRIWNETTILKSTEMCVIGANDR TMVTESDGRTWITREPAICYFHARQWFNVIGMLREDGVHYYCNISSPFAYDGEAIKYI DYDLDVKVFPDMTYNILDEDEYDDHRKAMNYPKEIDSILRDYLNTLLHWIHQRQGPFA PEFVDMWYERYLRYTK*" gene 938731..939261 /gene="ygaC" /locus_tag="BSU_08680" /old_locus_tag="BSU08680" downshifts 939252 /Source="Nicolas_upshifts" /id="D433" /incds=0 /nref=8 /ntot=135 /MaxReadThrough="6.10669" /MaxDrop="3.97335" /score="-5.22328881" /energy="-7" /TU="U667" /idTUdmin="U666" /TUdmin=0 /isTUend="TRUE" CDS 939349..941091 /gene="ygaD" /locus_tag="BSU_08690" /old_locus_tag="BSU08690" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative ABC transporter (ATP-binding protein)" /protein_id="NP_388749.2" /db_xref="EnsemblGenomes-Gn:BSU08690" /db_xref="EnsemblGenomes-Tr:CAB12697" /db_xref="GOA:P71082" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR011527" /db_xref="InterPro:IPR017871" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR036640" /db_xref="SubtiList:BG12224" /db_xref="UniProtKB/Swiss-Prot:P71082" /translation="MGVMKRYMQFVKPYKKQIFVTVLIGIVKFSIPLALPLLLKYVVD DIIQGGGTASDKTTSLFTIMAIMFALFLILRPPVEYYRQYFAQWTASKVLYDIRAKLF DHIQKLSLRFYANTRTGEVISRVINDVEQTKDFVITGLMNIWLDMLTILIVISIMLTL DVKLTLISIVLFPLYGISVKYFYGRLRKLTRERSQALAQVQGHLHERIQGMPVIRSFA IEDHEQAQFNEKNGHFLDKAIRHTNWNAKTFAVVNTITDLAPLIVIACAGYFVINGPL TVGTMVAFVGYIDRMYNPVRRLINSSTTLTQSIASMDRVFEFIDEPYELTDKPNAIKA DQIRGGVEFQNVSFQYEKDKENILHDVSLKVNRGETVALVGMSGGGKSTLVSLIPRFY DVTSGRLLIDGTDIRDYEARSLRNQVGMVLQDTFLFSETIRENIAIGKPDATLEEIIE AAKAANAHEFIMSFPEGYETRVGERGVKLSGGQKQRISIARVFLKNPPLLILDEATSA LDLESEHYIQEAMDKLAKDRTTFVVAHRLSTITHADKIVVMENGTIIEIGTHDELMDY ESQYKHLFTIQNLN*" gene 939349..941091 /gene="ygaD" /locus_tag="BSU_08690" /old_locus_tag="BSU08690" downshifts 941078 /Source="Nicolas_upshifts" /id="D434" /incds=0 /nref=87 /ntot=233 /MaxReadThrough="2.54676" /MaxDrop="5.20475" /score="22.3853226" /energy="-14.1" /TU="NA" /idTUdmin="U667" /TUdmin=0 /isTUend="TRUE" CDS complement(941168..942229) /gene="ygaE" /locus_tag="BSU_08700" /old_locus_tag="BSU08700" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative membrane protein" /protein_id="NP_388750.1" /db_xref="EnsemblGenomes-Gn:BSU08700" /db_xref="EnsemblGenomes-Tr:CAB12698" /db_xref="GOA:P71083" /db_xref="InterPro:IPR010343" /db_xref="SubtiList:BG12225" /db_xref="UniProtKB/Swiss-Prot:P71083" /translation="MKLGARIFKTGIAITLALYLASWIGLPAPIFAGIAAIFAIQPSI YRSFLIIIDQVQANIIGAVIATVFGLIFGPSPIMIGLTAVIVITIMLKLKIEHTISIA LVTVIAILESAGDDFLMFALIRTSTVILGVLSSFIVNLVFLPPKYETKLIHNTVENTE EIMKWIRLSMRQSTEHSILKEDIEKLKEKMIKLDQTYLLYKEERSYFKKTTYVKSRKL VLFRQAIITANRALDTLKKLHRLENEIYHMPEEFQETLTEELDYLLYWHERILMRFVG KIKPHDDAVEEGIRYKQLLTKSFLKNQQNTDEELIDYNMLNIMASAVEYREQLEHLET LITSFQTYHPKDCEIETEE*" gene complement(941168..942229) /gene="ygaE" /locus_tag="BSU_08700" /old_locus_tag="BSU08700" downshifts complement(941179) /Source="Nicolas_upshifts" /id="D435" /incds=0 /nref=181 /ntot=254 /MaxReadThrough="1.1413" /MaxDrop="7.13599" /score="26.0617552" /energy="-9.4" /TU="NA" /idTUdmin="U668" /TUdmin="-3" /isTUend="TRUE" S_feature complement(942230..942320) /Source="Nicolas_S_feature" /locus_tag="new_942230_942320_c" /HighExp="G180, Oxctl, Paraq, C30, G150, LBGexp, LPhT, S4, G135, S5" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.998" /TUlongSig="NA" /TUlongPSig="NA" /label="S300" promotor_-10 complement(942318..942337) /Source="Nicolas_upshift_promotors" /id="U668" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.502497502497502" /psig="0.998001998001998" /xcortree=2441 /SigmaFactorBS="aagattttggtctttttctagaaaaataGCTTGAATatttgt atcgatccCTGTATATTACTTAATTGTTtagcaaataaactaaccgggaattttaagg a" /listShort="S300, ygaE" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(942327) /Source="Nicolas_upshifts" /id="U668" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.502497502497502" /psig="0.998001998001998" /xcortree=2441 /SigmaFactorBS="aagattttggtctttttctagaaaaataGCTTGAATatttgt atcgatccCTGTATATTACTTAATTGTTtagcaaataaactaaccgggaattttaagg a" /listShort="S300, ygaE" /GFF_Attribute="listLong" promotor_-35 complement(942352..942359) /Source="Nicolas_upshift_promotors" /id="U668" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.502497502497502" /psig="0.998001998001998" /xcortree=2441 /SigmaFactorBS="aagattttggtctttttctagaaaaataGCTTGAATatttgt atcgatccCTGTATATTACTTAATTGTTtagcaaataaactaaccgggaattttaagg a" /listShort="S300, ygaE" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(942449..943738) /gene="gsaB" /locus_tag="BSU_08710" /old_locus_tag="BSU08710" /EC_number="5.4.3.8" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2b: Function from indirect experimental evidences (e.g. phenotypes); PubMedId: 15231799, 19930658; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="glutamate-1-semialdehyde aminotransferase, classIII aminotransferase" /protein_id="NP_388751.3" /db_xref="EnsemblGenomes-Gn:BSU08710" /db_xref="EnsemblGenomes-Tr:CAB12699" /db_xref="GOA:P71084" /db_xref="InterPro:IPR004639" /db_xref="InterPro:IPR005814" /db_xref="InterPro:IPR015421" /db_xref="InterPro:IPR015422" /db_xref="InterPro:IPR015424" /db_xref="SubtiList:BG11943" /db_xref="UniProtKB/Swiss-Prot:P71084" /translation="MHTKSIELHNEALQHIVGGVNSPSRSYKAVGGGSPVAMEKASGA YFWDVDGNKYIDYLAAYGPIITGHAHPHITEAIKKAAENGVLYGTPTKHEVTFAKMLK EAIPAMDKVRFVNSGTEAVMTTIRVARAYTGRTKIIKFAGCYHGHSDLVLVAAGSGPS TLGTPDSAGVPKSIANEVITVPFNDIDSYKAALEKWGSEIAAVLVEPIVGNFGIVEPK EGFLEQVNELTHNAGALVIYDEVITAFRFMYGGAQDLLQVKPDLTALGKIIGGGLPIG AYGGKQEIMEQVAPLGPAYQAGTMAGNPASILSGIACLEVLKEKGVYEKLDHLGAMLE EGILKHAETHGITITVNRLKGALTVYFSDEKVENYEQAERSDGETFSTFFKLMLERGI NLAPSKYEAWFITTAHTEQDIKDTLTAVEDAFKHLKN*" gene complement(942449..943738) /gene="gsaB" /locus_tag="BSU_08710" /old_locus_tag="BSU08710" downshifts complement(942452) /Source="Nicolas_upshifts" /id="D436" /incds=0 /nref=235 /ntot=258 /MaxReadThrough="2.54961" /MaxDrop="5.8522" /score="29.5551149" /energy="-11" /TU="NA" /idTUdmin="U669" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(943766..943785) /Source="Nicolas_upshift_promotors" /id="U669" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.998001998001998" /psig=1 /xcortree=1888 /SigmaFactorBS="tccagattacaaccatctcagctgaatctgaagcccgaagcc aTTGTTCttgttcggaagCATGCTACAATAGAAAGGACgcatggagatataggaggtt t" /listShort="gsaB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(943785) /Source="Nicolas_upshifts" /id="U669" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.998001998001998" /psig=1 /xcortree=1888 /SigmaFactorBS="tccagattacaaccatctcagctgaatctgaagcccgaagcc aTTGTTCttgttcggaagCATGCTACAATAGAAAGGACgcatggagatataggaggtt t" /listShort="gsaB" /GFF_Attribute="listLong" S_feature complement(943787..944498) /Source="Nicolas_S_feature" /locus_tag="new_943787_944498_c" /HighExp="LoTm, M9-stat, B60, S8, C30, Cold, B36, T1.30H, Etha, T2.0H" /AntisenseName="ygaF" /AntisenseCor="-0.29702219161000198" /AntisenseRegPval="-6.2" /CDS_PredictionProba="NA" /TUshortSig="NA" /TUshortPSig="NA" /TUlongSig="NA" /TUlongPSig="NA" /label="S301" promotor_-35 complement(943797..943802) /Source="Nicolas_upshift_promotors" /id="U669" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.998001998001998" /psig=1 /xcortree=1888 /SigmaFactorBS="tccagattacaaccatctcagctgaatctgaagcccgaagcc aTTGTTCttgttcggaagCATGCTACAATAGAAAGGACgcatggagatataggaggtt t" /listShort="gsaB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 943831..943838 /Source="Nicolas_upshift_promotors" /id="U670" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.625374625374625" /psig=1 /xcortree=2268 /SigmaFactorBS="aacaagaacaatggcttcgggcttcagattcagctgagaTGG TTGTAatctggacaagaaTTGGATACGCTTAATAAAAAaacatccggaggtaacgtaa t" /listShort="ygaF, perR" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 943852..943871 /Source="Nicolas_upshift_promotors" /id="U670" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.625374625374625" /psig=1 /xcortree=2268 /SigmaFactorBS="aacaagaacaatggcttcgggcttcagattcagctgagaTGG TTGTAatctggacaagaaTTGGATACGCTTAATAAAAAaacatccggaggtaacgtaa t" /listShort="ygaF, perR" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 943852 /Source="Nicolas_upshifts" /id="U670" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.625374625374625" /psig=1 /xcortree=2268 /SigmaFactorBS="aacaagaacaatggcttcgggcttcagattcagctgagaTGG TTGTAatctggacaagaaTTGGATACGCTTAATAAAAAaacatccggaggtaacgtaa t" /listShort="ygaF, perR" /GFF_Attribute="listLong" CDS 943891..944364 /gene="bcp" /locus_tag="BSU_08720" /old_locus_tag="BSU08720" /EC_number="1.11.1.15" /function="16.8: Protect" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 10644761, 11349039, 12950915, 21910476, 26723255; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="peroxiredoxin with versatile activity" /protein_id="YP_054574.1" /db_xref="EnsemblGenomes-Gn:BSU08720" /db_xref="EnsemblGenomes-Tr:CAB12700" /db_xref="GOA:Q796Y8" /db_xref="InterPro:IPR000866" /db_xref="InterPro:IPR013766" /db_xref="InterPro:IPR024706" /db_xref="InterPro:IPR036249" /db_xref="SubtiList:BG12226" /db_xref="UniProtKB/Swiss-Prot:Q796Y8" /translation="MTIEIGQKAPDLELKGDHGETVKLSDYKGKYIVLYFYPKDMTPG CTTEACDFRDSHESFAELDAVIIGVSPDSQEKHGKFKEKHNLPFLLLVDDEHKLAEAF DVWKLKKNFGKEYMGIERSTFLIDKEGRLIKEWRKVKVKDHVAEALQTLKDMSEK*" gene 943891..944364 /gene="bcp" /locus_tag="BSU_08720" /old_locus_tag="BSU08720" promotor_-35 944401..944408 /Source="Nicolas_upshift_promotors" /id="U671" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.608391608391608" /psig=1 /xcortree=1534 /SigmaFactorBS="ctatgagcctatgcttacttttaccctgatatCAATTGACaa attatcgtagaaAGAGTTACACTAATTATAAAcattacaatgtaagaattttttttag a" /listShort="perR" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 944423..944442 /Source="Nicolas_upshift_promotors" /id="U671" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.608391608391608" /psig=1 /xcortree=1534 /SigmaFactorBS="ctatgagcctatgcttacttttaccctgatatCAATTGACaa attatcgtagaaAGAGTTACACTAATTATAAAcattacaatgtaagaattttttttag a" /listShort="perR" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 944429 /Source="Nicolas_upshifts" /id="U671" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.608391608391608" /psig=1 /xcortree=1534 /SigmaFactorBS="ctatgagcctatgcttacttttaccctgatatCAATTGACaa attatcgtagaaAGAGTTACACTAATTATAAAcattacaatgtaagaattttttttag a" /listShort="perR" /GFF_Attribute="listLong" CDS 944487..944924 /gene="perR" /locus_tag="BSU_08730" /old_locus_tag="BSU08730" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:1580225, 16541078, 16925555, 22194458, 27935957, 22720735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1580225, 16541078, 16925555, 22194458, 27935957, 22720735; Product type r : regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator (Fur family)" /protein_id="NP_388753.1" /db_xref="EnsemblGenomes-Gn:BSU08730" /db_xref="EnsemblGenomes-Tr:CAB12701" /db_xref="GOA:P71086" /db_xref="InterPro:IPR002481" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="PDB:2FE3" /db_xref="PDB:2RGV" /db_xref="PDB:3F8N" /db_xref="SubtiList:BG12227" /db_xref="UniProtKB/Swiss-Prot:P71086" /translation="MAAHELKEALETLKETGVRITPQRHAILEYLVNSMAHPTADDIY KALEGKFPNMSVATVYNNLRVFRESGLVKELTYGDASSRFDFVTSDHYHAICENCGKI VDFHYPGLDEVEQLAAHVTGFKVSHHRLEIYGVCQECSKKENH*" gene 944487..944924 /gene="perR" /locus_tag="BSU_08730" /old_locus_tag="BSU08730" downshifts 944906 /Source="Nicolas_upshifts" /id="D437" /incds=0 /nref=149 /ntot=247 /MaxReadThrough="3.98479" /MaxDrop="7.52234" /score="1.62878623" /energy="-12.3" /TU="U670,U671" /idTUdmin="U670" /TUdmin="-66" /isTUend="FALSE" CDS complement(944959..945312) /gene="ygzB" /locus_tag="BSU_08740" /old_locus_tag="BSU08740" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative membrane protein" /protein_id="YP_054575.1" /db_xref="EnsemblGenomes-Gn:BSU08740" /db_xref="EnsemblGenomes-Tr:CAE01450" /db_xref="GOA:Q7WY74" /db_xref="InterPro:IPR020912" /db_xref="SubtiList:BG14192" /db_xref="UniProtKB/Swiss-Prot:Q7WY74" /translation="MAKYSSKINKIRTFALSLVFVGFIIMYIGIFFKESVLLSSLFMI LGLLSIGLSTVVYFWIGMLSTKAVRVICPGCDKETKVLGVVDMCMHCREPLTLDKGLE GKEFDESYNKKKMSK*" gene complement(944959..945312) /gene="ygzB" /locus_tag="BSU_08740" /old_locus_tag="BSU08740" downshifts 944972 /Source="Nicolas_upshifts" /id="D438" /incds=0 /nref=1 /ntot=40 /MaxReadThrough="2.62283" /MaxDrop="4.13562" /score="-4.23596421" /energy="-12.5" /TU="NA" /idTUdmin="U670" /TUdmin=0 /isTUend="TRUE" downshifts complement(944982) /Source="Nicolas_upshifts" /id="D439" /incds=0 /nref=182 /ntot=253 /MaxReadThrough="4.02571" /MaxDrop="6.23378" /score="9.51667757" /energy="-14.2" /TU="NA" /idTUdmin="U673" /TUdmin=0 /isTUend="TRUE" promotor_-35 945308..945312 /Source="Nicolas_upshift_promotors" /id="U672" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.892107892107892" /psig="0.0739260739260739" /xcortree=2130 /SigmaFactorBS="ttaacgcaaatgttctgattttattaattttgctggagtatt tcGCCATgtccatcCCCCTCTGTTTTAACtatagcacaaacccgatgggattttcttc a" /listShort="S302, S303, ygxA" /listLong="S304, rrnD-16S" /label="promotor_-35" promotor_-10 945320..945334 /Source="Nicolas_upshift_promotors" /id="U672" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.892107892107892" /psig="0.0739260739260739" /xcortree=2130 /SigmaFactorBS="ttaacgcaaatgttctgattttattaattttgctggagtatt tcGCCATgtccatcCCCCTCTGTTTTAACtatagcacaaacccgatgggattttcttc a" /listShort="S302, S303, ygxA" /listLong="S304, rrnD-16S" /label="promotor_-10" misc_feature complement(945324..945343) /Source="Nicolas_upshift_promotors" /id="U673" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.949050949050949" /psig="0.998001998001998" /xcortree=432 /SigmaFactorBS="catatgtaaattccagttcaaccgaaaacatgaagaaaatcc catcgggttTGTGCTATAGTTAAAACAGAgggggatggacatggcgaaatactccagc a" /listShort="ygzB" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" S_feature 945324..945415 /Source="Nicolas_S_feature" /locus_tag="new_945324_945415" /HighExp="Cold, C30, H2O2, Etha, dia15, G135, Paraq, C90, G180, G150" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="Sig-" /TUshortPSig="0.0739" /TUlongSig="NA" /TUlongPSig="NA" /label="S302" upshifts 945324 /Source="Nicolas_upshifts" /id="U672" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.892107892107892" /psig="0.0739260739260739" /xcortree=2130 /SigmaFactorBS="ttaacgcaaatgttctgattttattaattttgctggagtatt tcGCCATgtccatcCCCCTCTGTTTTAACtatagcacaaacccgatgggattttcttc a" /listShort="S302, S303, ygxA" /listLong="S304, rrnD-16S" upshifts complement(945334) /Source="Nicolas_upshifts" /id="U673" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.949050949050949" /psig="0.998001998001998" /xcortree=432 /SigmaFactorBS="catatgtaaattccagttcaaccgaaaacatgaagaaaatcc catcgggttTGTGCTATAGTTAAAACAGAgggggatggacatggcgaaatactccagc a" /listShort="ygzB" /GFF_Attribute="listLong" promotor_-35 945392..945395 /Source="Nicolas_upshift_promotors" /id="U674" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.736263736263736" /psig="0.996003996003996" /xcortree=95 /SigmaFactorBS="tttcttcatgttttcggttgaactggaatttacatATGGaga gttactgtgaaATTGTTTATAATAGTTCAATgtgtttagaaaaaaggaatttcgtttt a" /listShort="S303, ygxA, S304" /listLong="rrnD-16S" /label="promotor_-35" promotor_-10 945410..945429 /Source="Nicolas_upshift_promotors" /id="U674" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.736263736263736" /psig="0.996003996003996" /xcortree=95 /SigmaFactorBS="tttcttcatgttttcggttgaactggaatttacatATGGaga gttactgtgaaATTGTTTATAATAGTTCAATgtgtttagaaaaaaggaatttcgtttt a" /listShort="S303, ygxA, S304" /listLong="rrnD-16S" /label="promotor_-10" S_feature 945417..945519 /Source="Nicolas_S_feature" /locus_tag="new_945417_945519" /HighExp="BMM, Cold, LBGstat, C30, Oxctl, LBGexp, Paraq, G180, Lbexp, Heat" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, Sig-" /TUshortPSig="0.996, 0.0739" /TUlongSig="NA" /TUlongPSig="NA" /label="S303" upshifts 945417 /Source="Nicolas_upshifts" /id="U674" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.736263736263736" /psig="0.996003996003996" /xcortree=95 /SigmaFactorBS="tttcttcatgttttcggttgaactggaatttacatATGGaga gttactgtgaaATTGTTTATAATAGTTCAATgtgtttagaaaaaaggaatttcgtttt a" /listShort="S303, ygxA, S304" /listLong="rrnD-16S" CDS 945520..946404 /gene="ygxA" /locus_tag="BSU_08750" /old_locus_tag="BSU08750" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_388755.1" /db_xref="EnsemblGenomes-Gn:BSU08750" /db_xref="EnsemblGenomes-Tr:CAB12703" /db_xref="InterPro:IPR029348" /db_xref="InterPro:IPR036388" /db_xref="SubtiList:BG10951" /db_xref="UniProtKB/Swiss-Prot:Q04385" /translation="MENLLRPIYQERASHPNTLAVIMIERRNKTSSLTDNFDAALLVI VKDADEPVFIKHYEFDHQTASLHVVTDSQIQEWILLGTNRRIIDWIVNGRVLFDRNEY VVELIDRLNTFPFAERKLKIGLEYGKLIRRYVEGKAFFEANQFLDAYNAVVHALHHLA RIEVIDRGFHPETTVWSQVRQMEPQVYKLYSELIESHESLEKRLELLFLANDFLIHSK AEIGSAHLFEVMKEKDIWQFGELLQHHDLKHFTQDLGVMLDYLTEKGLINVCQIETKG QAVYHRGYSFKKGVDSDS*" gene 945520..946404 /gene="ygxA" /locus_tag="BSU_08750" /old_locus_tag="BSU08750" promotor_-35 946387..946394 /Source="Nicolas_upshift_promotors" /id="U675" /multdbtbs="SigA" /comp="M17" /sig="SigA" /pcomp="0.999000999001" /psig=1 /xcortree=2619 /SigmaFactorBS="cgaggatattcttttaaaaaaggtGTTGACTCtgattcttga ccgTGTTATATTATTAAACGTCGctgatgcgcttctgagaaaacaagctcacagcggc g" /listShort="S304, rrnD-16S" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 946408..946427 /Source="Nicolas_upshift_promotors" /id="U675" /multdbtbs="SigA" /comp="M17" /sig="SigA" /pcomp="0.999000999001" /psig=1 /xcortree=2619 /SigmaFactorBS="cgaggatattcttttaaaaaaggtGTTGACTCtgattcttga ccgTGTTATATTATTAAACGTCGctgatgcgcttctgagaaaacaagctcacagcggc g" /listShort="S304, rrnD-16S" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 946423..946695 /Source="Nicolas_S_feature" /locus_tag="new_946423_946695" /HighExp="LBGstat, Oxctl, C30, Paraq, GM 120, H2O2, HPh, G150, LPh, Cold" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.106881" /TUshortSig="SigA, SigA" /TUshortPSig="1, 0.996" /TUlongSig="Sig-" /TUlongPSig="0.0739" /label="S304" upshifts 946423 /Source="Nicolas_upshifts" /id="U675" /multdbtbs="SigA" /comp="M17" /sig="SigA" /pcomp="0.999000999001" /psig=1 /xcortree=2619 /SigmaFactorBS="cgaggatattcttttaaaaaaggtGTTGACTCtgattcttga ccgTGTTATATTATTAAACGTCGctgatgcgcttctgagaaaacaagctcacagcggc g" /listShort="S304, rrnD-16S" /GFF_Attribute="listLong" downshifts complement(946456) /Source="Nicolas_upshifts" /id="D440" /incds=0 /nref=1 /ntot=20 /MaxReadThrough="2.70619" /MaxDrop="3.85046" /score="4.43428373" /energy="-7.8" /TU="NA" /idTUdmin="U673" /TUdmin="-1474" /isTUend="FALSE" rRNA 946696..948250 /gene="rrnD-16S" /locus_tag="BSU_rRNA_22" /product="ribosomal RNA-16S" /note="Evidence 1a: Function from experimental evidences in the studied strain; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene 946696..948250 /gene="rrnD-16S" /locus_tag="BSU_rRNA_22" rRNA 948418..951345 /gene="rrnD-23S" /locus_tag="BSU_rRNA_17" /product="ribosomal RNA-23S" /note="Evidence 1a: Function from experimental evidences in the studied strain; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene 948418..951345 /gene="rrnD-23S" /locus_tag="BSU_rRNA_17" S_feature 951346..951431 /Source="Nicolas_S_feature" /locus_tag="new_951346_951431" /HighExp="G135, C30, Oxctl, Paraq, LBGstat, dia0, HiTm, Fru, G180, Cold" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="NA" /TUshortPSig="NA" /TUlongSig="NA" /TUlongPSig="NA" /label="S305" promotor_-35 951407..951414 /Source="Nicolas_upshift_promotors" /id="U676" /multdbtbs="SigA" /comp="M17" /sig="SigA" /pcomp="0.852147852147852" /psig=1 /xcortree=2417 /SigmaFactorBS="ctagttttgagagaataagtttttcaaaaaaacaCTTGATTT tctcaagaatacaTAGTATAATGTTAAATGTCActgaaattgtctggtgatgatggcg a" /listShort="rrnD-5S, trnD-Asn, trnD-Ser, trnD-Glu, trnD-Val, trnD-Met, trnD-Asp, trnD-Phe, trnD-Thr, trnD-Tyr, trnD-Trp, trnD-His, trnD-Gln, trnD-Gly, trnD-Cys, trnD-Leu1, S306, S307, trnD-Leu2, ygzA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 951428..951447 /Source="Nicolas_upshift_promotors" /id="U676" /multdbtbs="SigA" /comp="M17" /sig="SigA" /pcomp="0.852147852147852" /psig=1 /xcortree=2417 /SigmaFactorBS="ctagttttgagagaataagtttttcaaaaaaacaCTTGATTT tctcaagaatacaTAGTATAATGTTAAATGTCActgaaattgtctggtgatgatggcg a" /listShort="rrnD-5S, trnD-Asn, trnD-Ser, trnD-Glu, trnD-Val, trnD-Met, trnD-Asp, trnD-Phe, trnD-Thr, trnD-Tyr, trnD-Trp, trnD-His, trnD-Gln, trnD-Gly, trnD-Cys, trnD-Leu1, S306, S307, trnD-Leu2, ygzA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 951433 /Source="Nicolas_upshifts" /id="U676" /multdbtbs="SigA" /comp="M17" /sig="SigA" /pcomp="0.852147852147852" /psig=1 /xcortree=2417 /SigmaFactorBS="ctagttttgagagaataagtttttcaaaaaaacaCTTGATTT tctcaagaatacaTAGTATAATGTTAAATGTCActgaaattgtctggtgatgatggcg a" /listShort="rrnD-5S, trnD-Asn, trnD-Ser, trnD-Glu, trnD-Val, trnD-Met, trnD-Asp, trnD-Phe, trnD-Thr, trnD-Tyr, trnD-Trp, trnD-His, trnD-Gln, trnD-Gly, trnD-Cys, trnD-Leu1, S306, S307, trnD-Leu2, ygzA" /GFF_Attribute="listLong" rRNA 951457..951572 /gene="rrnD-5S" /locus_tag="BSU_rRNA_18" /product="ribosomal RNA-5S" /note="Evidence 1a: Function from experimental evidences in the studied strain; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene 951457..951572 /gene="rrnD-5S" /locus_tag="BSU_rRNA_18" tRNA 951582..951656 /gene="asnTA" /locus_tag="BSU_tRNA_29" /product="tRNA-Asn" /inference="profile:tRNAscan:1.23" /note="asparagine transfer RNA (GUU); Evidence 2a: Function from experimental evidences in other organisms; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene 951582..951656 /gene="asnTA" /locus_tag="BSU_tRNA_29" tRNA 951662..951753 /gene="trnD-Ser" /locus_tag="BSU_tRNA_30" /product="tRNA-Ser" /inference="profile:tRNAscan:1.23" /note="transfer RNA-Ser(GGA); Evidence 2a: Function from experimental evidences in other organisms; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene 951662..951753 /gene="trnD-Ser" /locus_tag="BSU_tRNA_30" downshifts 951749 /Source="Nicolas_upshifts" /id="D441" /incds=0 /nref=2 /ntot=20 /MaxReadThrough="7.64297" /MaxDrop="4.37505" /score="-9.7424199" /energy="-11" /TU="U676" /idTUdmin="U677" /TUdmin="-1562" /isTUend="FALSE" tRNA 951788..951859 /gene="trnD-Glu" /locus_tag="BSU_tRNA_31" /product="tRNA-Glu" /inference="profile:tRNAscan:1.23" /note="transfer RNA-Glu(UUC); Evidence 1a: Function from experimental evidences in the studied strain; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene 951788..951859 /gene="trnD-Glu" /locus_tag="BSU_tRNA_31" tRNA 951869..951944 /gene="trnD-Val" /locus_tag="BSU_tRNA_32" /product="tRNA-Val" /inference="profile:tRNAscan:1.23" /note="transfer RNA-Val(UAC); Evidence 1a: Function from experimental evidences in the studied strain; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene 951869..951944 /gene="trnD-Val" /locus_tag="BSU_tRNA_32" tRNA 951954..952030 /gene="trnD-Met" /locus_tag="BSU_tRNA_33" /product="tRNA-Met" /inference="profile:tRNAscan:1.23" /note="transfer RNA-Met(CAU); Evidence 2a: Function from experimental evidences in other organisms; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene 951954..952030 /gene="trnD-Met" /locus_tag="BSU_tRNA_33" tRNA 952042..952118 /gene="trnD-Asp" /locus_tag="BSU_tRNA_34" /product="tRNA-Asp" /inference="profile:tRNAscan:1.23" /note="transfer RNA-Asp(GUC); Evidence 1a: Function from experimental evidences in the studied strain; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene 952042..952118 /gene="trnD-Asp" /locus_tag="BSU_tRNA_34" tRNA 952131..952206 /gene="trnD-Phe" /locus_tag="BSU_tRNA_35" /product="tRNA-Phe" /inference="profile:tRNAscan:1.23" /note="transfer RNA-Phe(GAA); Evidence 2a: Function from experimental evidences in other organisms; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene 952131..952206 /gene="trnD-Phe" /locus_tag="BSU_tRNA_35" tRNA 952212..952284 /gene="trnD-Thr" /locus_tag="BSU_tRNA_36" /product="tRNA-Thr" /inference="profile:tRNAscan:1.23" /note="transfer RNA-Thr(UGU); Evidence 2a: Function from experimental evidences in other organisms; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene 952212..952284 /gene="trnD-Thr" /locus_tag="BSU_tRNA_36" tRNA 952307..952391 /gene="trnD-Tyr" /locus_tag="BSU_tRNA_37" /product="tRNA-Tyr" /inference="profile:tRNAscan:1.23" /note="transfer RNA-Tyr(GUA); Evidence 1a: Function from experimental evidences in the studied strain; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene 952307..952391 /gene="trnD-Tyr" /locus_tag="BSU_tRNA_37" tRNA 952397..952470 /gene="trnD-Trp" /locus_tag="BSU_tRNA_38" /product="tRNA-Trp" /inference="profile:tRNAscan:1.23" /note="transfer RNA-Trp(CCA); Evidence 1a: Function from experimental evidences in the studied strain; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene 952397..952470 /gene="trnD-Trp" /locus_tag="BSU_tRNA_38" tRNA 952495..952570 /gene="trnD-His" /locus_tag="BSU_tRNA_39" /product="tRNA-His" /inference="profile:tRNAscan:1.23" /note="transfer RNA-His(GUG); Evidence 2a: Function from experimental evidences in other organisms; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene 952495..952570 /gene="trnD-His" /locus_tag="BSU_tRNA_39" tRNA 952580..952651 /gene="trnD-Gln" /locus_tag="BSU_tRNA_40" /product="tRNA-Gln" /inference="profile:tRNAscan:1.23" /note="transfer RNA-Gln(UUG); Evidence 2a: Function from experimental evidences in other organisms; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene 952580..952651 /gene="trnD-Gln" /locus_tag="BSU_tRNA_40" tRNA 952701..952775 /gene="glyTB" /locus_tag="BSU_tRNA_41" /product="tRNA-Gly" /inference="profile:tRNAscan:1.23" /note="glycine transfer RNA (GCC); Evidence 1a: Function from experimental evidences in the studied strain; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene 952701..952775 /gene="glyTB" /locus_tag="BSU_tRNA_41" tRNA 952781..952851 /gene="cysTA" /locus_tag="BSU_tRNA_42" /product="tRNA-Cys" /inference="profile:tRNAscan:1.23" /note="cysteine tRNA (GCA); Evidence 2a: Function from experimental evidences in other organisms; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene 952781..952851 /gene="cysTA" /locus_tag="BSU_tRNA_42" tRNA 952859..952947 /gene="leuTA" /locus_tag="BSU_tRNA_43" /product="tRNA-Leu" /inference="profile:tRNAscan:1.23" /note="leucine RNA (UAA); Evidence 2a: Function from experimental evidences in other organisms; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene 952859..952947 /gene="leuTA" /locus_tag="BSU_tRNA_43" S_feature 952948..953024 /Source="Nicolas_S_feature" /locus_tag="new_952948_953024" /HighExp="Paraq, C30, Oxctl, G180, G135, Heat, BMM, LBGexp, dia15, Cold" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S306" downshifts 952981 /Source="Nicolas_upshifts" /id="D442" /incds=0 /nref=18 /ntot=231 /MaxReadThrough="5.36857" /MaxDrop="5.05259" /score="16.6649124" /energy="-8.9" /TU="U676" /idTUdmin="U677" /TUdmin="-330" /isTUend="FALSE" S_feature 953026..953194 /Source="Nicolas_S_feature" /locus_tag="new_953026_953194" /HighExp="Heat, Paraq, BMM, Oxctl, H2O2, Cold, G180, Pyr, C30, Glu" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S307" promotor_-35 953151..953158 /Source="Nicolas_upshift_promotors" /id="U677" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.927072927072927" /psig="0.998001998001998" /xcortree=687 /SigmaFactorBS="acttttttgaaatacGTTGACACtttatgagatccaTGATAT ATTTATATTCGTCGgttagatacgacgtaaaacttgccggtgtggcggaattggcaga c" /listShort="trnD-Leu2" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 953157 /Source="Nicolas_upshifts" /id="D443" /incds=0 /nref=1 /ntot=14 /MaxReadThrough="3.84674" /MaxDrop="3.439" /score="35.1424037" /energy="-12.4" /TU="U676" /idTUdmin="U677" /TUdmin="-154" /isTUend="FALSE" promotor_-10 953172..953191 /Source="Nicolas_upshift_promotors" /id="U677" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.927072927072927" /psig="0.998001998001998" /xcortree=687 /SigmaFactorBS="acttttttgaaatacGTTGACACtttatgagatccaTGATAT ATTTATATTCGTCGgttagatacgacgtaaaacttgccggtgtggcggaattggcaga c" /listShort="trnD-Leu2" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 953196 /Source="Nicolas_upshifts" /id="U677" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.927072927072927" /psig="0.998001998001998" /xcortree=687 /SigmaFactorBS="acttttttgaaatacGTTGACACtttatgagatccaTGATAT ATTTATATTCGTCGgttagatacgacgtaaaacttgccggtgtggcggaattggcaga c" /listShort="trnD-Leu2" /GFF_Attribute="listLong" tRNA 953213..953294 /gene="leuTB" /locus_tag="BSU_tRNA_44" /product="tRNA-Leu" /inference="profile:tRNAscan:1.23" /note="leucine tRNA(CAA); Evidence 2a: Function from experimental evidences in other organisms; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene 953213..953294 /gene="leuTB" /locus_tag="BSU_tRNA_44" promotor_-10 complement(953230..953247) /Source="Nicolas_upshift_promotors" /id="U678" /multdbtbs="-" /comp="M20" /sig="Sig-" /pcomp="0.925074925074925" /psig="0.012987012987013" /xcortree=395 /SigmaFactorBS="accggtggtcggggtcgaacCGACACtccagaaggaacacga ttttGAGTCGTGCGCGTCTGCCaattccgccacaccggcaagttttacgtcgtatcta a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(953233) /Source="Nicolas_upshifts" /id="U678" /multdbtbs="-" /comp="M20" /sig="Sig-" /pcomp="0.925074925074925" /psig="0.012987012987013" /xcortree=395 /SigmaFactorBS="accggtggtcggggtcgaacCGACACtccagaaggaacacga ttttGAGTCGTGCGCGTCTGCCaattccgccacaccggcaagttttacgtcgtatcta a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(953268..953273) /Source="Nicolas_upshift_promotors" /id="U678" /multdbtbs="-" /comp="M20" /sig="Sig-" /pcomp="0.925074925074925" /psig="0.012987012987013" /xcortree=395 /SigmaFactorBS="accggtggtcggggtcgaacCGACACtccagaaggaacacga ttttGAGTCGTGCGCGTCTGCCaattccgccacaccggcaagttttacgtcgtatcta a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" downshifts complement(953303) /Source="Nicolas_upshifts" /id="D444" /incds=0 /nref=5 /ntot=151 /MaxReadThrough="1.64364" /MaxDrop="6.28675" /score="7.71223568" /energy="-12.4" /TU="NA" /idTUdmin="U679" /TUdmin=18 /isTUend="TRUE" CDS complement(953373..954149) /gene="spo0M" /locus_tag="BSU_08760" /old_locus_tag="BSU08760" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:9795118, 22142536, 26625291, 28234965" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9795118, 22142536, 26625291, 28234965; Product type r: regulator" /codon_start=1 /transl_table=11 /product="protein involved in the control of the cell cycle as a function of the environment" /protein_id="NP_388756.2" /db_xref="EnsemblGenomes-Gn:BSU08760" /db_xref="EnsemblGenomes-Tr:CAB12704" /db_xref="GOA:P71088" /db_xref="InterPro:IPR009776" /db_xref="InterPro:IPR014756" /db_xref="PDB:5CL2" /db_xref="SubtiList:BG12229" /db_xref="UniProtKB/Swiss-Prot:P71088" /translation="MSFFKKLAASAGIGAAKVDTILEKDAYFPGEEVQGTVHVKGGKI AQDIRYIDLQLSTRYVIVKDDEEHRKYATIHSFRVTGSFTIQPGEEHQFPFTFTLPLD TPITVGKVEVAVVTDLDIQGGIDKSDHDRIFVEAHPWIENVLEAIENLGFRLNEADCE QAPYFQRRLPFVQEFEFVPTSGYYRQMLDELELIFLLDEDGLEIIFEVDRRARGLRGW LEEMYNDGEQLVRVRFSQSELEDTEELEEVLEEILDQYAE*" gene complement(953373..954149) /gene="spo0M" /locus_tag="BSU_08760" /old_locus_tag="BSU08760" downshifts complement(953387) /Source="Nicolas_upshifts" /id="D445" /incds=0 /nref=9 /ntot=131 /MaxReadThrough="6.06864" /MaxDrop="6.58787" /score="6.75662782" /energy="-7" /TU="U679" /idTUdmin="U679" /TUdmin="-66" /isTUend="FALSE" promotor_-10 complement(954176..954191) /Source="Nicolas_upshift_promotors" /id="U679" /multdbtbs="SigH" /comp="M9" /sig="SigWXY" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1665 /SigmaFactorBS="tgtccctaggccgagacgaataataggaaaaaagtatgaatc aaaCGAATCTTTTttcctccttcttACGTATATCTGTTGAGaaaaaagaaaaagggga a" /listShort="spo0M" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(954198) /Source="Nicolas_upshifts" /id="U679" /multdbtbs="SigH" /comp="M9" /sig="SigWXY" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1665 /SigmaFactorBS="tgtccctaggccgagacgaataataggaaaaaagtatgaatc aaaCGAATCTTTTttcctccttcttACGTATATCTGTTGAGaaaaaagaaaaagggga a" /listShort="spo0M" /GFF_Attribute="listLong" promotor_-35 complement(954204..954213) /Source="Nicolas_upshift_promotors" /id="U679" /multdbtbs="SigH" /comp="M9" /sig="SigWXY" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1665 /SigmaFactorBS="tgtccctaggccgagacgaataataggaaaaaagtatgaatc aaaCGAATCTTTTttcctccttcttACGTATATCTGTTGAGaaaaaagaaaaagggga a" /listShort="spo0M" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 954233..954239 /Source="Nicolas_upshift_promotors" /id="U680" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.995004995004995" /psig="0.995004995004995" /xcortree=873 /SigmaFactorBS="ggaggaaaaaagattcgtttgattcatacttttttcCTATTA TtcgtctcggcctagGGACAGACTAAGaataatattgaaaataaaggagtcgatggaa g" /listShort="ygzA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 954254..954265 /Source="Nicolas_upshift_promotors" /id="U680" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.995004995004995" /psig="0.995004995004995" /xcortree=873 /SigmaFactorBS="ggaggaaaaaagattcgtttgattcatacttttttcCTATTA TtcgtctcggcctagGGACAGACTAAGaataatattgaaaataaaggagtcgatggaa g" /listShort="ygzA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 954257 /Source="Nicolas_upshifts" /id="U680" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.995004995004995" /psig="0.995004995004995" /xcortree=873 /SigmaFactorBS="ggaggaaaaaagattcgtttgattcatacttttttcCTATTA TtcgtctcggcctagGGACAGACTAAGaataatattgaaaataaaggagtcgatggaa g" /listShort="ygzA" /GFF_Attribute="listLong" CDS 954291..954494 /gene="ygzA" /locus_tag="BSU_08770" /old_locus_tag="BSU08770" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_388757.2" /db_xref="EnsemblGenomes-Gn:BSU08770" /db_xref="EnsemblGenomes-Tr:CAB12705" /db_xref="SubtiList:BG12981" /db_xref="UniProtKB/Swiss-Prot:O31586" /translation="MEVNKESLVADELHRMFLAGELQITVEEDINNISERLRNGDLSL DRLSGEDVFIKETVNEALRRVEQ*" gene 954291..954494 /gene="ygzA" /locus_tag="BSU_08770" /old_locus_tag="BSU08770" downshifts 954477 /Source="Nicolas_upshifts" /id="D446" /incds=0 /nref=22 /ntot=97 /MaxReadThrough="1.47004" /MaxDrop="5.47861" /score="15.4081475" /energy="-18.2" /TU="NA" /idTUdmin="U676" /TUdmin=0 /isTUend="TRUE" downshifts complement(954553) /Source="Nicolas_upshifts" /id="D447" /incds=0 /nref=10 /ntot=35 /MaxReadThrough="1.31339" /MaxDrop="4.8918" /score="26.0684119" /energy="-18.2" /TU="NA" /idTUdmin="U681" /TUdmin=0 /isTUend="TRUE" CDS complement(954579..954851) /gene="ygzC" /locus_tag="BSU_08779" /old_locus_tag="BSU08779" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type s: structure" /codon_start=1 /transl_table=11 /product="putative spore coat protein" /protein_id="YP_003097696.1" /db_xref="EnsemblGenomes-Gn:BSU08779" /db_xref="EnsemblGenomes-Tr:CAX52583" /db_xref="GOA:C0H3X8" /db_xref="InterPro:IPR012347" /db_xref="InterPro:IPR012851" /db_xref="UniProtKB/Swiss-Prot:C0H3X8" /translation="MYRSKKQSQILSYQELLKKQRRWFPIEQSLCPKDILDLLTTIKT SINKYTVATTATENPHIRRALHDQLDTAVYLHDELSDLLLEKGWLG*" gene complement(954579..954851) /gene="ygzC" /locus_tag="BSU_08779" /old_locus_tag="BSU08779" promotor_-10 complement(954810..954828) /Source="Nicolas_upshift_promotors" /id="U681" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.94005994005994" /psig="0.94005994005994" /xcortree=1185 /SigmaFactorBS="caaaatttgttgcttattatagcatttTGTATAgaagcaaga aacaaagTCAAATACTTTCTTATCAGgagctgctaaaaaaacaaaggaggtggtttcc c" /listShort="ygzC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(954817) /Source="Nicolas_upshifts" /id="U681" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.94005994005994" /psig="0.94005994005994" /xcortree=1185 /SigmaFactorBS="caaaatttgttgcttattatagcatttTGTATAgaagcaaga aacaaagTCAAATACTTTCTTATCAGgagctgctaaaaaaacaaaggaggtggtttcc c" /listShort="ygzC" /GFF_Attribute="listLong" promotor_-35 954832..954839 /Source="Nicolas_upshift_promotors" /id="U682" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.478521478521479" /psig=1 /xcortree=2885 /SigmaFactorBS="ttagcagctcctgataagaaagtatttgacttTGTTTCTTgc ttctatacaaAATGCTATAATAAGCAACAAattttgttggggggtgtgatgatgaagc a" /listShort="ygaJ" /listLong="NA, thiC, S308" /label="promotor_-35" promotor_-35 complement(954845..954850) /Source="Nicolas_upshift_promotors" /id="U681" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.94005994005994" /psig="0.94005994005994" /xcortree=1185 /SigmaFactorBS="caaaatttgttgcttattatagcatttTGTATAgaagcaaga aacaaagTCAAATACTTTCTTATCAGgagctgctaaaaaaacaaaggaggtggtttcc c" /listShort="ygzC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 954852..954871 /Source="Nicolas_upshift_promotors" /id="U682" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.478521478521479" /psig=1 /xcortree=2885 /SigmaFactorBS="ttagcagctcctgataagaaagtatttgacttTGTTTCTTgc ttctatacaaAATGCTATAATAAGCAACAAattttgttggggggtgtgatgatgaagc a" /listShort="ygaJ" /listLong="NA, thiC, S308" /label="promotor_-10" upshifts 954860 /Source="Nicolas_upshifts" /id="U682" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.478521478521479" /psig=1 /xcortree=2885 /SigmaFactorBS="ttagcagctcctgataagaaagtatttgacttTGTTTCTTgc ttctatacaaAATGCTATAATAAGCAACAAattttgttggggggtgtgatgatgaagc a" /listShort="ygaJ" /listLong="NA, thiC, S308" CDS 954893..955585 /gene="ygaJ" /locus_tag="BSU_08780" /old_locus_tag="BSU08780" /EC_number="3.4.21.-" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative peptidase" /protein_id="NP_388758.2" /db_xref="EnsemblGenomes-Gn:BSU08780" /db_xref="EnsemblGenomes-Tr:CAB12706" /db_xref="GOA:P71089" /db_xref="InterPro:IPR005320" /db_xref="InterPro:IPR029062" /db_xref="SubtiList:BG12230" /db_xref="UniProtKB/Swiss-Prot:P71089" /translation="MKQIIAMGGGGFSMEPDNLSLDQYILNQSKREQPRICFLPTASG DSQNYIQRFYHAFQTLDCVPSHLSLFKPPSSDLVSFVMEMDVIYVGGGNTRNLLVLWK EWGLDHILREAWKNGVVVAGISAGAICWFEEGVTDSAGPLTSLKSLGFLQGSFCPHYD GEKDRRPAYHQLISNKFLCSGYAADDGAALHFINDQLFQTVSSRSGAKAYRVMMAEHE IAEIPLPVKYLG*" gene 954893..955585 /gene="ygaJ" /locus_tag="BSU_08780" /old_locus_tag="BSU08780" promotor_-35 955614..955618 /Source="Nicolas_upshift_promotors" /id="U684" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.616383616383616" /psig="0.946053946053946" /xcortree=2883 /SigmaFactorBS="tctatattcctcTTTTTttcagattgatttTATGATAAGATG AGTGCGAAatcaatagttactgggggtgcccgctttcgggctgagagagaaggcaagc t" /listShort="NA, thiC, S308" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(955617..955636) /Source="Nicolas_upshift_promotors" /id="U683" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.863136863136863" /psig="0.997002997002997" /xcortree=2976 /SigmaFactorBS="tctcagcccgaaagcgggcacccccagtaacTATTGATTtcg cactcatcttaTCATAAAATCAATCTGAAAAaaagaggaatatagataatattcagcc a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(955629) /Source="Nicolas_upshifts" /id="U683" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.863136863136863" /psig="0.997002997002997" /xcortree=2976 /SigmaFactorBS="tctcagcccgaaagcgggcacccccagtaacTATTGATTtcg cactcatcttaTCATAAAATCAATCTGAAAAaaagaggaatatagataatattcagcc a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 955632..955651 /Source="Nicolas_upshift_promotors" /id="U684" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.616383616383616" /psig="0.946053946053946" /xcortree=2883 /SigmaFactorBS="tctatattcctcTTTTTttcagattgatttTATGATAAGATG AGTGCGAAatcaatagttactgggggtgcccgctttcgggctgagagagaaggcaagc t" /listShort="NA, thiC, S308" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 complement(955651..955658) /Source="Nicolas_upshift_promotors" /id="U683" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.863136863136863" /psig="0.997002997002997" /xcortree=2976 /SigmaFactorBS="tctcagcccgaaagcgggcacccccagtaacTATTGATTtcg cactcatcttaTCATAAAATCAATCTGAAAAaaagaggaatatagataatattcagcc a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" misc_RNA 955655..955762 /gene="tswD" /locus_tag="BSU_misc_RNA_11" /product="thiamine pyrophosphate riboswitch" /note="Evidence 1c: Function from experimental evidences in the studied genus; PubMedId: 11470904, 12410317, 15862294, 16728979, 16962976, 17307816, 18179415, 18776013; Product type n: RNA" /function="16.3: Control" gene 955655..955762 /gene="tswD" /locus_tag="BSU_misc_RNA_11" upshifts 955662 /Source="Nicolas_upshifts" /id="U684" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.616383616383616" /psig="0.946053946053946" /xcortree=2883 /SigmaFactorBS="tctatattcctcTTTTTttcagattgatttTATGATAAGATG AGTGCGAAatcaatagttactgggggtgcccgctttcgggctgagagagaaggcaagc t" /listShort="NA, thiC, S308" /GFF_Attribute="listLong" downshifts 955793 /Source="Nicolas_upshifts" /id="D448" /incds=0 /nref=13 /ntot=48 /MaxReadThrough="8.09735" /MaxDrop="5.74046" /score="17.5556194" /energy="-12.4" /TU="U684" /idTUdmin="U682" /TUdmin=152 /isTUend="FALSE" CDS 955895..957667 /gene="thiC" /locus_tag="BSU_08790" /old_locus_tag="BSU08790" /EC_number="4.1.99.17" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:8432721, 9370266, 10382260, 16291685, 26443755" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8432721, 9370266, 10382260, 16291685, 26443755; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="phosphomethylpyrimidine synthase" /protein_id="NP_388759.2" /db_xref="EnsemblGenomes-Gn:BSU08790" /db_xref="EnsemblGenomes-Tr:CAB12707" /db_xref="GOA:P45740" /db_xref="InterPro:IPR002817" /db_xref="InterPro:IPR025747" /db_xref="SubtiList:BG11246" /db_xref="UniProtKB/Swiss-Prot:P45740" /translation="MQNNSVQQANISIMSSFSGSKKVYVEGSSSDIQVPMREIALSPT TGSFGEEENAPVRVYDTSGPYTDPEVTINIQEGLKPLRQKWITERGDVEEYEGRAIKP EDNGYKKAKPNVSYPGLKRKPLRAKAGQNVTQMHYAKKGIITPEMEFIAIREHVSPEF VRDEVASGRAIIPSNINHPESEPMIIGRNFHVKINANIGNSAVTSSIEEEVEKMTWAI RWGADTMMDLSTGKDIHTTREWIIRNCPVPVGTVPIYQALEKVNGVAEDLTWEIYRDT LIEQAEQGVDYFTIHAGVLLRYVPLTAKRTTGIVSRGGAIMAQWCLAHHQESFLYTHF EEICEIMKMYDIAFSLGDGLRPGSIADANDEAQFAELETLGELTQIAWKHDVQVMIEG PGHVPMHKIKENVDKQMDICKEAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWYGTAM LCYVTPKEHLGLPNRDDVREGVITYKIAAHAADLAKGHPGAQIRDDALSKARFEFRWR DQFNLSLDPERALEYHDETLPAEGAKTAHFCSMCGPKFCSMRISQDIRDYAKKNDLSE AEAINKGLKEKAKEFVDTGSNLYQ*" gene 955895..957667 /gene="thiC" /locus_tag="BSU_08790" /old_locus_tag="BSU08790" downshifts 957643 /Source="Nicolas_upshifts" /id="D449" /incds=0 /nref=166 /ntot=257 /MaxReadThrough="5.77069" /MaxDrop="5.3684" /score="25.2366359" /energy="-15.3" /TU="U684" /idTUdmin="U684" /TUdmin="-946" /isTUend="FALSE" S_feature 957688..958613 /Source="Nicolas_S_feature" /locus_tag="new_957688_958613" /HighExp="HiOs, GM-0.1, GM 45, GM 60, GM-0.2, BMM, MG 90, T-5.40H, MG 15, MG 25" /AntisenseName="ygaK" /AntisenseCor="-9.7288827054566707E-2" /AntisenseRegPval="-1" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.946" /TUlongSig="SigA" /TUlongPSig=1 /label="S308" CDS complement(957705..959060) /gene="ygaK" /locus_tag="BSU_08800" /old_locus_tag="BSU08800" /EC_number="1.21.-.-" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 8972604; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative FAD-dependent oxido-reductase" /protein_id="NP_388760.2" /db_xref="EnsemblGenomes-Gn:BSU08800" /db_xref="EnsemblGenomes-Tr:CAB12708" /db_xref="GOA:Q796Y5" /db_xref="InterPro:IPR006094" /db_xref="InterPro:IPR012951" /db_xref="InterPro:IPR016166" /db_xref="InterPro:IPR016167" /db_xref="InterPro:IPR016169" /db_xref="InterPro:IPR036318" /db_xref="SubtiList:BG12231" /db_xref="UniProtKB/Swiss-Prot:Q796Y5" /translation="MEKTKLTGRIVTRDDPDYNEARTNINLSLERYPDIIVFCQNKQD ALNALKWARENRVPFRIRGGRHSYENFSLLNNGLVIDLSEMKKITVNQDKKLAYIEAG AELGEVYRTLWQYGLTLPAGTIANVGLTGLTLGGGIGLLTRAAGLTCDSLVQLEMIVA DEKEGADLITVSCSNHPDLFWASQGGGGGNFGIVTSMTFKAVPISQVSIFSITWGWDD FEEVYNTWQNWAPYTDDRLTSSIEFWPKEVNRIEALGQFVGPKTELKKLLKPLLKAGS PTSGMVKTTPFIEAVTFFNSPGGNQPQKMKRSGSFIEKPLSERAISTIKHFLEHAPNQ NASVWQQALGGAAGRVAPDQTAFYYRDAIIAQEYLTNWTSPGEKRQNVRWIEGLRTSL SKETMGDYVNWPDIEIRNWPRTYYGENVERLRRVKTTYDPENVFRFEQSIPPLRRSLF F*" gene complement(957705..959060) /gene="ygaK" /locus_tag="BSU_08800" /old_locus_tag="BSU08800" promotor_-10 complement(959088..959107) /Source="Nicolas_upshift_promotors" /id="U685" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1414 /SigmaFactorBS="tgttgacactgtatcagattgcatccccgctttttCCTTATA CACtcttttcccctgaCGCATAAGCTAGAGAAACTAgaatacgagagaaagagatgtg g" /listShort="ygaK" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(959105) /Source="Nicolas_upshifts" /id="U685" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1414 /SigmaFactorBS="tgttgacactgtatcagattgcatccccgctttttCCTTATA CACtcttttcccctgaCGCATAAGCTAGAGAAACTAgaatacgagagaaagagatgtg g" /listShort="ygaK" /GFF_Attribute="listLong" promotor_-35 complement(959121..959130) /Source="Nicolas_upshift_promotors" /id="U685" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1414 /SigmaFactorBS="tgttgacactgtatcagattgcatccccgctttttCCTTATA CACtcttttcccctgaCGCATAAGCTAGAGAAACTAgaatacgagagaaagagatgtg g" /listShort="ygaK" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 959178..959184 /Source="Nicolas_upshift_promotors" /id="U686" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.48951048951049" /psig="0.954045954045954" /xcortree=1737 /SigmaFactorBS="cctcaaaaaatAGTTGACaggtcggtattgtaTGAATTAACA TGGTCAGTACaaatttttcaaatttatcgcgctgatcggaacaccgaaggctcttatc g" /listShort="senS" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 959199..959218 /Source="Nicolas_upshift_promotors" /id="U686" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.48951048951049" /psig="0.954045954045954" /xcortree=1737 /SigmaFactorBS="cctcaaaaaatAGTTGACaggtcggtattgtaTGAATTAACA TGGTCAGTACaaatttttcaaatttatcgcgctgatcggaacaccgaaggctcttatc g" /listShort="senS" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 959227 /Source="Nicolas_upshifts" /id="U686" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.48951048951049" /psig="0.954045954045954" /xcortree=1737 /SigmaFactorBS="cctcaaaaaatAGTTGACaggtcggtattgtaTGAATTAACA TGGTCAGTACaaatttttcaaatttatcgcgctgatcggaacaccgaaggctcttatc g" /listShort="senS" /GFF_Attribute="listLong" CDS 959311..959508 /gene="senS" /locus_tag="BSU_08810" /old_locus_tag="BSU08810" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:1479343, 2108127, 8323536, 16321961" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1479343, 2108127, 8323536, 16321961; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator (repressor of ScoC)" /protein_id="NP_388761.2" /db_xref="EnsemblGenomes-Gn:BSU08810" /db_xref="EnsemblGenomes-Tr:CAB12709" /db_xref="GOA:P21344" /db_xref="InterPro:IPR025004" /db_xref="SubtiList:BG10747" /db_xref="UniProtKB/Swiss-Prot:P21344" /translation="MGVKKEKGRKRFRKRKTYGNQILPLELLIEKNKREIINSAELME EIYMKIDEKHTQCVTKYKKTR*" gene 959311..959508 /gene="senS" /locus_tag="BSU_08810" /old_locus_tag="BSU08810" CDS complement(959535..960986) /gene="katA" /locus_tag="BSU_08820" /old_locus_tag="BSU08820" /EC_number="1.11.1.6" /function="16.11: Scavenge (Catabolism)" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:12029044, 12486061, 16535198, 22194458, 27935957" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12029044, 12486061, 16535198, 22194458, 27935957; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="vegetative catalase 1" /protein_id="NP_388762.2" /db_xref="EnsemblGenomes-Gn:BSU08820" /db_xref="EnsemblGenomes-Tr:CAB12710" /db_xref="GOA:P26901" /db_xref="InterPro:IPR002226" /db_xref="InterPro:IPR010582" /db_xref="InterPro:IPR011614" /db_xref="InterPro:IPR018028" /db_xref="InterPro:IPR020835" /db_xref="InterPro:IPR024708" /db_xref="InterPro:IPR024711" /db_xref="InterPro:IPR037060" /db_xref="SubtiList:BG10849" /db_xref="UniProtKB/Swiss-Prot:P26901" /translation="MSSNKLTTSWGAPVGDNQNSMTAGSRGPTLIQDVHLLEKLAHFN RERVPERVVHAKGAGAHGYFEVTNDVTKYTKAAFLSEVGKRTPLFIRFSTVAGELGSA DTVRDPRGFAVKFYTEEGNYDIVGNNTPVFFIRDAIKFPDFIHTQKRDPKTHLKNPTA VWDFWSLSPESLHQVTILMSDRGIPATLRHMHGFGSHTFKWTNAEGEGVWIKYHFKTE QGVKNLDVNTAAKIAGENPDYHTEDLFNAIENGDYPAWKLYVQIMPLEDANTYRFDPF DVTKVWSQKDYPLIEVGRMVLDRNPENYFAEVEQATFSPGTLVPGIDVSPDKMLQGRL FAYHDAHRYRVGANHQALPINRARNKVNNYQRDGQMRFDDNGGGSVYYEPNSFGGPKE SPEDKQAAYPVQGIADSVSYDHYDHYTQAGDLYRLMSEDERTRLVENIVNAMKPVEKE EIKLRQIEHFYKADPEYGKRVAEGLGLPIKKDS*" gene complement(959535..960986) /gene="katA" /locus_tag="BSU_08820" /old_locus_tag="BSU08820" downshifts complement(959545) /Source="Nicolas_upshifts" /id="D450" /incds=0 /nref=221 /ntot=261 /MaxReadThrough="1.32399" /MaxDrop="8.8938" /score="25.1548262" /energy="-8.3" /TU="NA" /idTUdmin="U688" /TUdmin=0 /isTUend="TRUE" promotor_-35 960963..960969 /Source="Nicolas_upshift_promotors" /id="U687" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.382617382617383" /psig="0.528471528471528" /xcortree=1222 /SigmaFactorBS="tgagttttgattatctccaaccggagcgccccagctAGTTGT CagtttatttgaactCATGTTATCACCTCTTGGAAtttataagaacataatatcatct c" /listShort="S309, ssuB, ssuA, ssuC, ssuD, ygaN" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 960984..961003 /Source="Nicolas_upshift_promotors" /id="U687" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.382617382617383" /psig="0.528471528471528" /xcortree=1222 /SigmaFactorBS="tgagttttgattatctccaaccggagcgccccagctAGTTGT CagtttatttgaactCATGTTATCACCTCTTGGAAtttataagaacataatatcatct c" /listShort="S309, ssuB, ssuA, ssuC, ssuD, ygaN" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 960987 /Source="Nicolas_upshifts" /id="U687" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.382617382617383" /psig="0.528471528471528" /xcortree=1222 /SigmaFactorBS="tgagttttgattatctccaaccggagcgccccagctAGTTGT CagtttatttgaactCATGTTATCACCTCTTGGAAtttataagaacataatatcatct c" /listShort="S309, ssuB, ssuA, ssuC, ssuD, ygaN" /GFF_Attribute="listLong" promotor_-10 complement(961004..961023) /Source="Nicolas_upshift_promotors" /id="U688" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.99000999000999" /psig=1 /xcortree=1533 /SigmaFactorBS="attaatagagataactattttataataattataaaataaTAT TGACTttttacttagagaTGATATTATGTTCTTATAAAttccaagaggtgataacatg a" /listShort="katA" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 961009..961338 /Source="Nicolas_S_feature" /locus_tag="new_961009_961338" /HighExp="S8, C30, S7, S6, BT, C90, B36, S4, S5, S1" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.528" /TUlongSig="NA" /TUlongPSig="NA" /label="S309" upshifts complement(961023) /Source="Nicolas_upshifts" /id="U688" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.99000999000999" /psig=1 /xcortree=1533 /SigmaFactorBS="attaatagagataactattttataataattataaaataaTAT TGACTttttacttagagaTGATATTATGTTCTTATAAAttccaagaggtgataacatg a" /listShort="katA" /GFF_Attribute="listLong" promotor_-35 complement(961037..961044) /Source="Nicolas_upshift_promotors" /id="U688" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.99000999000999" /psig=1 /xcortree=1533 /SigmaFactorBS="attaatagagataactattttataataattataaaataaTAT TGACTttttacttagagaTGATATTATGTTCTTATAAAttccaagaggtgataacatg a" /listShort="katA" /GFF_Attribute="listLong" /label="promotor_-35" misc_feature complement(961082..961100) /Source="Nicolas_upshift_promotors" /id="U689" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.351648351648352" /psig="0.602397602397602" /xcortree=647 /SigmaFactorBS="gaaaaattatttctccaaaaattattaagtgtcataaaaagc tgttacaacaaggtttttcaacaatTTCGATACTATATATCGATtaatagagataact a" /listShort="katA" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(961107) /Source="Nicolas_upshifts" /id="U689" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.351648351648352" /psig="0.602397602397602" /xcortree=647 /SigmaFactorBS="gaaaaattatttctccaaaaattattaagtgtcataaaaagc tgttacaacaaggtttttcaacaatTTCGATACTATATATCGATtaatagagataact a" /listShort="katA" /GFF_Attribute="listLong" downshifts 961295 /Source="Nicolas_upshifts" /id="D451" /incds=0 /nref=9 /ntot=21 /MaxReadThrough="5.89897" /MaxDrop="4.66837" /score="39.0049465" /energy="-19.7" /TU="U687" /idTUdmin="U686" /TUdmin=1936 /isTUend="FALSE" CDS 961394..962161 /gene="ssuB" /locus_tag="BSU_08830" /old_locus_tag="BSU08830" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 9782504, 11390694, 16513748, 16885442; Product type t: transporter" /codon_start=1 /transl_table=11 /product="aliphatic sulfonate ABC transporter (ATP-bindingprotein)" /protein_id="NP_388763.3" /db_xref="EnsemblGenomes-Gn:BSU08830" /db_xref="EnsemblGenomes-Tr:CAB12711" /db_xref="GOA:P97027" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR017871" /db_xref="InterPro:IPR017875" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG12232" /db_xref="UniProtKB/Swiss-Prot:P97027" /translation="MAVTISIKEKAFVQEGRKNTVLENIELSIAPGEFLTLIGPSGCG KSTLLKIIAGLDSEYDGSVEINGRSVTAPGIQQGFIFQEHRLFPWLTVEQNIAADLNL KDPKVKQKVDELIEIVRLKGSEKAYPRELSGGMSQRVAIARALLREPEVLLLDEPFGA LDAFTRKHLQDVLLDIWRKKKTTMILVTHDIDESVYLGNELAILKAKPGKIHKLMPIH LAYPRNRTTPDFQAIRQRVLSEFEKTEDLEYAEGSGI*" gene 961394..962161 /gene="ssuB" /locus_tag="BSU_08830" /old_locus_tag="BSU08830" CDS 962179..963177 /gene="ssuA" /locus_tag="BSU_08840" /old_locus_tag="BSU08840" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 9782504, 11390694, 16513748, 16885442; Product type f: factor" /codon_start=1 /transl_table=11 /product="aliphatic sulfonate ABC transporter (binding lipoprotein)" /protein_id="NP_388764.1" /db_xref="EnsemblGenomes-Gn:BSU08840" /db_xref="EnsemblGenomes-Tr:CAB12712" /db_xref="GOA:P40400" /db_xref="InterPro:IPR001638" /db_xref="InterPro:IPR010067" /db_xref="InterPro:IPR015168" /db_xref="SubtiList:BG10656" /db_xref="UniProtKB/Swiss-Prot:P40400" /translation="MKKGLIVLVAVIFLLAGCGANGASGDHKQLKEIRIGIQQSLSPL LIAKEKGWFEDAFEKEGIKVKWVEFQSGPPQFEGLAADKLDFSQVGNSPVIAGQAAGI DFKEIGLSQDGLKANGILVNQNSGIQDVKGLKGKKIAVAKGSSGFDFLYKALDQVGLS ANDVTIIQLQPDEAASAFENGSVDAWSIWEPYLSLETMKHGAKILVNGESTDLYSPGF TLVRTKFSEEHPDEVVRFLKVFNKAVVWQKEHLDEAADLYSDIKDLDKKVVENVLKNT EPLNEIISDDIVKAQQETADFQFRTKAIDKKIDVKDVVDNTFIKKALEEHSSGGDQ*" gene 962179..963177 /gene="ssuA" /locus_tag="BSU_08840" /old_locus_tag="BSU08840" CDS 963174..964004 /gene="ssuC" /locus_tag="BSU_08850" /old_locus_tag="BSU08850" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:11390694, 15849754, 16513748, 16850406, 16885442, 9782504" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11390694, 15849754, 16513748, 16850406, 16885442, 9782504; Product type t : transporter" /codon_start=1 /transl_table=11 /product="aliphatic sulfonate ABC transporter (permease)" /protein_id="NP_388765.1" /db_xref="EnsemblGenomes-Gn:BSU08850" /db_xref="EnsemblGenomes-Tr:CAB12713" /db_xref="GOA:P40401" /db_xref="InterPro:IPR000515" /db_xref="InterPro:IPR035906" /db_xref="SubtiList:BG10657" /db_xref="UniProtKB/Swiss-Prot:P40401" /translation="MMKAEAAGSLPKTNAEAVRKKPGRKRYGWMKGLLLPAVIIAIWQ VIGGLGVVSATVLPTPVTIVLTFKELILSGELFGHLQISIYRAALGFLLGAGLGLMIG ILAGFSKRTELYLDPSLQMLRTVPHLAVTPLFILWFGFDEVSKILLIALGAFFPVYIN TFNGIRGVDAKLFEVARVLEFKWHQQISKVILPAALPNILLGIRLSLGIAWLGLVVAE LMGSSSGVGYMIMDARQFSQTNKVFAGIIIFAVVGKLTDSFVRLLERKLLKWRNSYEG *" gene 963174..964004 /gene="ssuC" /locus_tag="BSU_08850" /old_locus_tag="BSU08850" CDS 964027..965157 /gene="ssuD" /locus_tag="BSU_08860" /old_locus_tag="BSU08860" /EC_number="1.14.14.5" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:9782504, 11390694, 16513748, 16885442" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9782504, 11390694, 16513748, 16885442; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="FMNH2-dependent aliphatic sulfonate monooxygenase" /protein_id="NP_388766.2" /db_xref="EnsemblGenomes-Gn:BSU08860" /db_xref="EnsemblGenomes-Tr:CAB12714" /db_xref="GOA:P40402" /db_xref="InterPro:IPR011251" /db_xref="InterPro:IPR019911" /db_xref="InterPro:IPR036661" /db_xref="SubtiList:BG10658" /db_xref="UniProtKB/Swiss-Prot:P40402" /translation="MEILWFIPTHGDARYLGSESDGRTADHLYFKQVAQAADRLGYTG VLLPTGRSCEDPWLTASALAGETKDLKFLVAVRPGLMQPSLAARMTSTLDRISDGRLL INVVAGGDPYELAGDGLFISHDERYEATDEFLTVWRRLLQGETVSYEGKHIKVENSNL LFPPQQEPHPPIYFGGSSQAGIEAAAKHTDVYLTWGEPPEQVKEKIERVKKQAAKEGR SVRFGIRLHVIARETEQEAWEAAERLISHLDDDTIAKAQAALSRYDSSGQQRMAVLHQ GDRTKLEISPNLWAGIGLVRGGAGTALVGDPQTIADRIAEYQALGIESFIFSGYPHLE EAYYFAELVFPLLPFENDRTRKLQNKRGEAVGNTYFVKEKNA*" gene 964027..965157 /gene="ssuD" /locus_tag="BSU_08860" /old_locus_tag="BSU08860" misc_feature 965184..965203 /Source="Nicolas_upshift_promotors" /id="U690" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.974025974025974" /psig="0.994005994005994" /xcortree=1467 /SigmaFactorBS="ttattttgtcaaagagaaaaatgcatgagtttaactaaaata cagccccccgaaCATGGTATGATATTCAAAAAaagggggctttttttctgaaaacatt g" /listShort="ygaN, S310" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 965190 /Source="Nicolas_upshifts" /id="U690" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.974025974025974" /psig="0.994005994005994" /xcortree=1467 /SigmaFactorBS="ttattttgtcaaagagaaaaatgcatgagtttaactaaaata cagccccccgaaCATGGTATGATATTCAAAAAaagggggctttttttctgaaaacatt g" /listShort="ygaN, S310" /GFF_Attribute="listLong" CDS 965261..965797 /gene="ygaN" /locus_tag="BSU_08870" /old_locus_tag="BSU08870" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 12193636, 16513748; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative sulfur-related oxidoreductase" /protein_id="NP_388767.1" /db_xref="EnsemblGenomes-Gn:BSU08870" /db_xref="EnsemblGenomes-Tr:CAB12715" /db_xref="SubtiList:BG12233" /db_xref="UniProtKB/Swiss-Prot:P97028" /translation="MLSACGHSKQMEIKAADISDLEKNRMDVAASQAFTAEAVNIGEG ISSADMYIEHYQKGKLVERFGPVRADYSEEKTDTIQFVYFENEEGEGKNKHTTIHFGI VDKQGTIAADSSVKRDDSTTQEMTQNISSPEPITFEKPALIGSSIRGTDETMHTSEHK KELIKHQDALLYYVELHH*" gene 965261..965797 /gene="ygaN" /locus_tag="BSU_08870" /old_locus_tag="BSU08870" S_feature 965798..965868 /Source="Nicolas_S_feature" /locus_tag="new_965798_965868" /HighExp="B36, BT, B60, Etha, S5, Heat, S2, BMM, S4, S3" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.25357200000000002" /TUshortSig="NA" /TUshortPSig="NA" /TUlongSig="NA" /TUlongPSig="NA" /label="S310" promotor_-35 965838..965845 /Source="Nicolas_upshift_promotors" /id="U691" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.718281718281718" /psig="0.999000999001" /xcortree=664 /SigmaFactorBS="caggccgtctgttttacaaagcggtatgCTTGCTTTtttgaa tggtgaaTGATACATTTTAAATCGTAAcaatttcgatttaaagggaggctatgtgact t" /listShort="rpsNB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 965859..965878 /Source="Nicolas_upshift_promotors" /id="U691" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.718281718281718" /psig="0.999000999001" /xcortree=664 /SigmaFactorBS="caggccgtctgttttacaaagcggtatgCTTGCTTTtttgaa tggtgaaTGATACATTTTAAATCGTAAcaatttcgatttaaagggaggctatgtgact t" /listShort="rpsNB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 965870 /Source="Nicolas_upshifts" /id="U691" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.718281718281718" /psig="0.999000999001" /xcortree=664 /SigmaFactorBS="caggccgtctgttttacaaagcggtatgCTTGCTTTtttgaa tggtgaaTGATACATTTTAAATCGTAAcaatttcgatttaaagggaggctatgtgact t" /listShort="rpsNB" /GFF_Attribute="listLong" CDS 965909..966178 /gene="rpsNB" /locus_tag="BSU_08880" /old_locus_tag="BSU08880" /function="16.2: Construct biomass (Anabolism)" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 12904577, 17163968, 19648245, 20208344, 27561249; Product type f: factor" /codon_start=1 /transl_table=11 /product="alternative ribosomal protein S14" /protein_id="NP_388768.1" /db_xref="EnsemblGenomes-Gn:BSU08880" /db_xref="EnsemblGenomes-Tr:CAB12716" /db_xref="GOA:O31587" /db_xref="InterPro:IPR001209" /db_xref="InterPro:IPR018271" /db_xref="InterPro:IPR023036" /db_xref="SubtiList:BG13085" /db_xref="UniProtKB/Swiss-Prot:O31587" /translation="MAKKSKVAKELKRQQLVEQYAGIRRELKEKGDYEALSKLPRDSA PGRLHNRCMVTGRPRAYMRKFKMSRIAFRELAHKGQIPGVKKASW*" gene 965909..966178 /gene="rpsNB" /locus_tag="BSU_08880" /old_locus_tag="BSU08880" promotor_-35 965981..965985 /Source="Nicolas_upshift_promotors" /id="U692" /multdbtbs="-" /comp="M20" /sig="Sig-" /pcomp="0.62037962037962" /psig="0.020979020979021" /xcortree=654 /SigmaFactorBS="aatacgctggtattagaCGCGAgttgaaggaaaaaggagatt acGAGGCACTCAGCAAGCTgccaagagattcagcaccgggaaggcttcacaaccgctg c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 966008..966024 /Source="Nicolas_upshift_promotors" /id="U692" /multdbtbs="-" /comp="M20" /sig="Sig-" /pcomp="0.62037962037962" /psig="0.020979020979021" /xcortree=654 /SigmaFactorBS="aatacgctggtattagaCGCGAgttgaaggaaaaaggagatt acGAGGCACTCAGCAAGCTgccaagagattcagcaccgggaaggcttcacaaccgctg c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 966024 /Source="Nicolas_upshifts" /id="U692" /multdbtbs="-" /comp="M20" /sig="Sig-" /pcomp="0.62037962037962" /psig="0.020979020979021" /xcortree=654 /SigmaFactorBS="aatacgctggtattagaCGCGAgttgaaggaaaaaggagatt acGAGGCACTCAGCAAGCTgccaagagattcagcaccgggaaggcttcacaaccgctg c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" downshifts 966165 /Source="Nicolas_upshifts" /id="D452" /incds=0 /nref=41 /ntot=70 /MaxReadThrough="3.14088" /MaxDrop="6.23701" /score="18.4402235" /energy="-10.1" /TU="U692" /idTUdmin="U691" /TUdmin="-13" /isTUend="TRUE" CDS complement(966196..966669) /gene="ygaO" /locus_tag="BSU_08890" /old_locus_tag="BSU08890" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative integral inner membrane protein" /protein_id="NP_388769.1" /db_xref="EnsemblGenomes-Gn:BSU08890" /db_xref="EnsemblGenomes-Tr:CAB12717" /db_xref="GOA:P97029" /db_xref="SubtiList:BG12234" /db_xref="UniProtKB/Swiss-Prot:P97029" /translation="MSMKTKAAFHLVLFGLACWALISYFEASEGIASFFGTKSGGMVF DLNLTPFILFVAASAVYLYLQKKSRPARKQLLLPDEFEEQDEREQMMTAKACRASYIA VYFSLPAAAVLLIFYPLFQSRIPFFPIIIVFIIMIIQHLSYVISFKKNEKNSGAL*" gene complement(966196..966669) /gene="ygaO" /locus_tag="BSU_08890" /old_locus_tag="BSU08890" downshifts complement(966232) /Source="Nicolas_upshifts" /id="D453" /incds=0 /nref=105 /ntot=235 /MaxReadThrough="1.59724" /MaxDrop="4.17785" /score="7.33161195" /energy="-10.1" /TU="NA" /idTUdmin="U693" /TUdmin=0 /isTUend="TRUE" CDS complement(966671..966871) /gene="ygzD" /locus_tag="BSU_08899" /old_locus_tag="BSU08899" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative HTH-type transcriptional regulator" /protein_id="YP_003097697.1" /db_xref="EnsemblGenomes-Gn:BSU08899" /db_xref="EnsemblGenomes-Tr:CAX52584" /db_xref="GOA:C0H3X9" /db_xref="InterPro:IPR001387" /db_xref="InterPro:IPR010982" /db_xref="UniProtKB/Swiss-Prot:C0H3X9" /translation="MKNKVKELRARFGYSQEKLGETVGVTRQTVAAIEKGDYVPSLLL ALKICKAFSMKMEDVFWLEEEN*" gene complement(966671..966871) /gene="ygzD" /locus_tag="BSU_08899" /old_locus_tag="BSU08899" promotor_-10 complement(966900..966919) /Source="Nicolas_upshift_promotors" /id="U693" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.626373626373626" /psig="0.996003996003996" /xcortree=1780 /SigmaFactorBS="aaaaaaagttatctttttgtaaagttgttaagttcCATTTAC AtaatgttaagtaTACTATACAATATAATCAATcgagattgtgaaggggacagacgtc a" /listShort="ygzD, ygaO" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(966914) /Source="Nicolas_upshifts" /id="U693" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.626373626373626" /psig="0.996003996003996" /xcortree=1780 /SigmaFactorBS="aaaaaaagttatctttttgtaaagttgttaagttcCATTTAC AtaatgttaagtaTACTATACAATATAATCAATcgagattgtgaaggggacagacgtc a" /listShort="ygzD, ygaO" /GFF_Attribute="listLong" promotor_-35 complement(966932..966939) /Source="Nicolas_upshift_promotors" /id="U693" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.626373626373626" /psig="0.996003996003996" /xcortree=1780 /SigmaFactorBS="aaaaaaagttatctttttgtaaagttgttaagttcCATTTAC AtaatgttaagtaTACTATACAATATAATCAATcgagattgtgaaggggacagacgtc a" /listShort="ygzD, ygaO" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 966995..967000 /Source="Nicolas_upshift_promotors" /id="U694" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.35964035964036" /psig=1 /xcortree=2589 /SigmaFactorBS="tacaaaaagataactttttttcgacaaaatttttatattccC TTGACgaaaaataaataaACATGTAATATAAAAAAAGTcagagcggtactgttgctga c" /listShort="trnSL-Gly1, S311, S312, yhbA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 967014..967033 /Source="Nicolas_upshift_promotors" /id="U694" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.35964035964036" /psig=1 /xcortree=2589 /SigmaFactorBS="tacaaaaagataactttttttcgacaaaatttttatattccC TTGACgaaaaataaataaACATGTAATATAAAAAAAGTcagagcggtactgttgctga c" /listShort="trnSL-Gly1, S311, S312, yhbA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 967014 /Source="Nicolas_upshifts" /id="U694" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.35964035964036" /psig=1 /xcortree=2589 /SigmaFactorBS="tacaaaaagataactttttttcgacaaaatttttatattccC TTGACgaaaaataaataaACATGTAATATAAAAAAAGTcagagcggtactgttgctga c" /listShort="trnSL-Gly1, S311, S312, yhbA" /GFF_Attribute="listLong" tRNA 967065..967138 /gene="trnSL-Gly1" /locus_tag="BSU_tRNA_82" /product="tRNA-Gly" /inference="profile:tRNAscan:1.23" /note="transfer RNA-Gly(TCC); Evidence 2a: Function from experimental evidences in other organisms; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene 967065..967138 /gene="trnSL-Gly1" /locus_tag="BSU_tRNA_82" S_feature 967139..967321 /Source="Nicolas_S_feature" /locus_tag="new_967139_967321" /HighExp="G135, G180, Oxctl, G150, Paraq, H2O2, C30, HPh, LPh, LBGexp" /AntisenseName="yhzB" /AntisenseCor="0.42714037049296899" /AntisenseRegPval="-12.6" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S311" CDS complement(967229..967852) /gene="yhzB" /locus_tag="BSU_08900" /old_locus_tag="BSU08900" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_388771.1" /db_xref="EnsemblGenomes-Gn:BSU08900" /db_xref="EnsemblGenomes-Tr:CAB12718" /db_xref="InterPro:IPR020825" /db_xref="SubtiList:BG13086" /db_xref="UniProtKB/Swiss-Prot:O31588" /translation="MNIKLDSVITERAAGLHAAAVIYENIEVGSSPQMLKGRLRLFQE SLFFDYADGGISDESFVKEWQKLFKQLNPSFEGETTPMEDMLVPISKEQFMESKDSAH DTIDFFALKYSLPIMIYDAGKLHEPVRISLGEKENILLFSDENGIFGDFKNSVNHYPV SNETKNMLQIIFFPPSIEKSSAVNLLSSLTKMFEQIHGGTHTVHWLT*" gene complement(967229..967852) /gene="yhzB" /locus_tag="BSU_08900" /old_locus_tag="BSU08900" downshifts complement(967244) /Source="Nicolas_upshifts" /id="D454" /incds=0 /nref=25 /ntot=165 /MaxReadThrough="2.50849" /MaxDrop="4.62652" /score="-8.52782087" /energy="-7.9" /TU="NA" /idTUdmin="U695" /TUdmin=0 /isTUend="TRUE" downshifts 967278 /Source="Nicolas_upshifts" /id="D455" /incds=0 /nref=1 /ntot=88 /MaxReadThrough="4.14204" /MaxDrop="2.36986" /score="16.0836885" /energy="-15.5" /TU="U694" /idTUdmin="U692" /TUdmin=1078 /isTUend="FALSE" S_feature 967323..967934 /Source="Nicolas_S_feature" /locus_tag="new_967323_967934" /HighExp="G180, G135, G150, Paraq, Oxctl, H2O2, LBGstat, Cold, LBGexp, S6" /AntisenseName="yhzB" /AntisenseCor="0.28959466335762701" /AntisenseRegPval="-5.9" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S312" promotor_-10 complement(967876..967895) /Source="Nicolas_upshift_promotors" /id="U695" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.631368631368631" /psig="0.999000999001" /xcortree=1953 /SigmaFactorBS="tctttgagctgataaacgttcatgttttgcacagcctccttT CTTTGTGataaaacgacacaGCGTTTATAATAGGTTGATAtcacgtaactggagtgaa t" /listShort="yhzB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(967897) /Source="Nicolas_upshifts" /id="U695" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.631368631368631" /psig="0.999000999001" /xcortree=1953 /SigmaFactorBS="tctttgagctgataaacgttcatgttttgcacagcctccttT CTTTGTGataaaacgacacaGCGTTTATAATAGGTTGATAtcacgtaactggagtgaa t" /listShort="yhzB" /GFF_Attribute="listLong" promotor_-35 complement(967909..967916) /Source="Nicolas_upshift_promotors" /id="U695" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.631368631368631" /psig="0.999000999001" /xcortree=1953 /SigmaFactorBS="tctttgagctgataaacgttcatgttttgcacagcctccttT CTTTGTGataaaacgacacaGCGTTTATAATAGGTTGATAtcacgtaactggagtgaa t" /listShort="yhzB" /GFF_Attribute="listLong" /label="promotor_-35" CDS 967935..969095 /gene="queG" /locus_tag="BSU_08910" /old_locus_tag="BSU08910" /EC_number="1.17.99.-" /function="10.3: tRNA and rRNA base modification" /experiment="publication(s) with functional evidences, PMID:8830270, 21502530, 26230193, 27638883, 28128549" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8830270, 21502530, 26230193, 27638883, 28128549; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="epoxyqueuosine reductase" /protein_id="NP_388772.2" /db_xref="EnsemblGenomes-Gn:BSU08910" /db_xref="EnsemblGenomes-Tr:CAB12719" /db_xref="GOA:P97030" /db_xref="InterPro:IPR004155" /db_xref="InterPro:IPR004453" /db_xref="InterPro:IPR013542" /db_xref="InterPro:IPR016024" /db_xref="InterPro:IPR017896" /db_xref="InterPro:IPR017900" /db_xref="PDB:5D08" /db_xref="PDB:5D0A" /db_xref="PDB:5D0B" /db_xref="PDB:5T8Y" /db_xref="SubtiList:BG12236" /db_xref="UniProtKB/Swiss-Prot:P97030" /translation="MNVYQLKEELIEYAKSIGVDKIGFTTADTFDSLKDRLILQESLG YLSGFEEPDIEKRVTPKLLLPKAKSIVAIALAYPSRMKDAPRSTRTERRGIFCRASWG KDYHDVLREKLDLLEDFLKSKHEDIRTKSMVDTGELSDRAVAERAGIGFSAKNCMITT PEYGSYVYLAEMITNIPFEPDVPIEDMCGSCTKCLDACPTGALVNPGQLNAQRCISFL TQTKGFLPDEFRTKIGNRLYGCDTCQTVCPLNKGKDFHLHPEMEPDPEIAKPLLKPLL AISNREFKEKFGHVSGSWRGKKPIQRNAILALAHFKDASALPELTELMHKDPRPVIRG TAAWAIGKIGDPAYAEELEKALEKEKDEEAKLEIEKGIELLKASGMTKQGLS*" gene 967935..969095 /gene="queG" /locus_tag="BSU_08910" /old_locus_tag="BSU08910" downshifts 969104 /Source="Nicolas_upshifts" /id="D456" /incds=0 /nref=9 /ntot=123 /MaxReadThrough="5.29174" /MaxDrop="3.3561" /score="33.0421154" /energy="-15.1" /TU="NA" /idTUdmin="U694" /TUdmin=0 /isTUend="TRUE" misc_feature 969121..969133 /Source="Nicolas_upshift_promotors" /id="U696" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.909090909090909" /psig="0.909090909090909" /xcortree=1143 /SigmaFactorBS="tcaggcatgactaaacaaggcctgtcctgacatacgtataga gcagaaggaaaaaACACTTGAGATCAtccaagtgttttttctctataaaaaagtatgg c" /listShort="yhbB, cspR" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 969126 /Source="Nicolas_upshifts" /id="U696" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.909090909090909" /psig="0.909090909090909" /xcortree=1143 /SigmaFactorBS="tcaggcatgactaaacaaggcctgtcctgacatacgtataga gcagaaggaaaaaACACTTGAGATCAtccaagtgttttttctctataaaaaagtatgg c" /listShort="yhbB, cspR" /GFF_Attribute="listLong" CDS 969162..970097 /gene="yhbB" /locus_tag="BSU_08920" /old_locus_tag="BSU08920" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_388773.1" /db_xref="EnsemblGenomes-Gn:BSU08920" /db_xref="EnsemblGenomes-Tr:CAB12720" /db_xref="InterPro:IPR024301" /db_xref="SubtiList:BG11811" /db_xref="UniProtKB/Swiss-Prot:O31589" /translation="MAGGVSLKYILEQLAEERLGFLVNGHAMRQESQVGDLKVMERKK KLLEKRKVDIIKAKAKAVINHVRVEDDGTTCLSYTIHYEYVCKEQDDSLYIEEHIEER MAFLYDHILISDQEIAKKPAGFHEGTSIIDYSEAEEEREAFGRAFQYDRLGAVQYAEK FWNKRNPAYKNFSDNCTNFISQCLHAGGAPMRGHPNRGSGWWMKQSSWSYSWTVAHSM KMYLSNSKAGLRAVRVKSAEELMPGDVICYDFEGDGRFNHTTIVVAKDKGNMPLVNAQ TYDSRMRYWSYEDSTAYTPSIRYAFFHIVDDTTKE*" gene 969162..970097 /gene="yhbB" /locus_tag="BSU_08920" /old_locus_tag="BSU08920" downshifts complement(969180) /Source="Nicolas_upshifts" /id="D457" /incds=0 /nref=2 /ntot=17 /MaxReadThrough="2.06584" /MaxDrop="3.33944" /score="-3.35852865" /energy="-6" /TU="NA" /idTUdmin="U695" /TUdmin="-1936" /isTUend="FALSE" promotor_-35 970081..970084 /Source="Nicolas_upshift_promotors" /id="U697" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.692307692307692" /psig=1 /xcortree=2502 /SigmaFactorBS="acacgccgtcaatacgatatgccttttttcatatcgttgatg ATACgacaaaagagtaattAATGTTATAATGATGGGCGGataagaaaaacagaggtga a" /listShort="cspR" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 970099 /Source="Nicolas_upshifts" /id="U697" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.692307692307692" /psig=1 /xcortree=2502 /SigmaFactorBS="acacgccgtcaatacgatatgccttttttcatatcgttgatg ATACgacaaaagagtaattAATGTTATAATGATGGGCGGataagaaaaacagaggtga a" /listShort="cspR" /GFF_Attribute="listLong" promotor_-10 970100..970119 /Source="Nicolas_upshift_promotors" /id="U697" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.692307692307692" /psig=1 /xcortree=2502 /SigmaFactorBS="acacgccgtcaatacgatatgccttttttcatatcgttgatg ATACgacaaaagagtaattAATGTTATAATGATGGGCGGataagaaaaacagaggtga a" /listShort="cspR" /GFF_Attribute="listLong" /label="promotor_-10" CDS 970135..970617 /gene="trmL" /locus_tag="BSU_08930" /old_locus_tag="BSU08930" /EC_number="2.1.1.207" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 12682299, 20855540; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="tRNA (cytidine(34)-2'-O)-methyltransferase" /protein_id="NP_388774.2" /db_xref="EnsemblGenomes-Gn:BSU08930" /db_xref="EnsemblGenomes-Tr:CAB12721" /db_xref="GOA:O31590" /db_xref="InterPro:IPR001537" /db_xref="InterPro:IPR016914" /db_xref="InterPro:IPR029026" /db_xref="InterPro:IPR029028" /db_xref="SubtiList:BG11802" /db_xref="UniProtKB/Swiss-Prot:O31590" /translation="MNIVALHVVLYQPEIPANTGNIARTCAATNTTLHLIRPLGFSTD DKMLKRAGLDYWEFVNVVYHDSLEELFEAYKKGKFFFITKFGQQPHTSFDYTDLDEDY FFVFGRETSGLPKDLIQNNMDRCLRLPMTEHVRSLNLSNTAAILVYEALRQQNYRDLK *" gene 970135..970617 /gene="trmL" /locus_tag="BSU_08930" /old_locus_tag="BSU08930" downshifts 970600 /Source="Nicolas_upshifts" /id="D458" /incds=0 /nref=203 /ntot=259 /MaxReadThrough="4.6846" /MaxDrop="7.03587" /score="33.0421154" /energy="-15.1" /TU="NA" /idTUdmin="U696" /TUdmin=0 /isTUend="TRUE" CDS 970667..971383 /gene="yhbD" /locus_tag="BSU_08940" /old_locus_tag="BSU08940" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type f: factor" /codon_start=1 /transl_table=11 /product="putative sporulation-related protein" /protein_id="NP_388775.1" /db_xref="EnsemblGenomes-Gn:BSU08940" /db_xref="EnsemblGenomes-Tr:CAB12722" /db_xref="InterPro:IPR025063" /db_xref="SubtiList:BG12237" /db_xref="UniProtKB/Swiss-Prot:P97032" /translation="MLCFVFGLNNVTVLCYNVPIKGAGLMEEQLISKKELLERTSISY GQLYRWKRKNLIPEEWFIRKSTFTGQETFFPREEILKRISMIQKMKENLSLDEMREML SPKMKDVSMTADELLHKGLVSRPALEAYSEDGGSPVFSSSDLLSLFVLEGLLQSGNVS LAEAKMAAEVLKKHDTEEIEKQTELIVLRKLGVTTCFIAAAADSILFESSVKVVERVD LLKASEELKTTFMQEGHQWM*" gene 970667..971383 /gene="yhbD" /locus_tag="BSU_08940" /old_locus_tag="BSU08940" promotor_-35 970687..970694 /Source="Nicolas_upshift_promotors" /id="U698" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.761238761238761" /psig=1 /xcortree=2394 /SigmaFactorBS="tttttgcggatgttgaaatgctttgtttcgtttttggGCTTA ACAacgtaacagtgttaTGTTACAATGTACCCATCAAaggagctggacttatggaaga a" /listShort="yhbD, yhbE, yhbF" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 970709..970728 /Source="Nicolas_upshift_promotors" /id="U698" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.761238761238761" /psig=1 /xcortree=2394 /SigmaFactorBS="tttttgcggatgttgaaatgctttgtttcgtttttggGCTTA ACAacgtaacagtgttaTGTTACAATGTACCCATCAAaggagctggacttatggaaga a" /listShort="yhbD, yhbE, yhbF" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 970710 /Source="Nicolas_upshifts" /id="U698" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.761238761238761" /psig=1 /xcortree=2394 /SigmaFactorBS="tttttgcggatgttgaaatgctttgtttcgtttttggGCTTA ACAacgtaacagtgttaTGTTACAATGTACCCATCAAaggagctggacttatggaaga a" /listShort="yhbD, yhbE, yhbF" /GFF_Attribute="listLong" CDS 971374..972087 /gene="yhbE" /locus_tag="BSU_08950" /old_locus_tag="BSU08950" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 12562816, 20617312; Product type cp:cell process" /codon_start=1 /transl_table=11 /product="conserved protein involved in sporulation" /protein_id="NP_388776.1" /db_xref="EnsemblGenomes-Gn:BSU08950" /db_xref="EnsemblGenomes-Tr:CAB12723" /db_xref="InterPro:IPR007607" /db_xref="SubtiList:BG10802" /db_xref="UniProtKB/Swiss-Prot:P39132" /translation="MDVVEKLVINGSGSSKGGTFQSVEINGSGTVAGDVECDTFSFNG NGKADGSVKAKAVTISGSGKIHGDVEAESIRMNGTGFIQGEVSAKQLKIAGSSTFGGT VKADGIDISGKAVMEADCETETFQSEGKCKISGLLNADQVIIKLSAGESYAREIGCRH LQVTCRKGMLTLLRLMPQPVLTAELIEGDVIELTNTKAKTVRGNKVIIGPDCQIETVE YSGDYTCDPSASVETSTKL*" gene 971374..972087 /gene="yhbE" /locus_tag="BSU_08950" /old_locus_tag="BSU08950" CDS 972099..972806 /gene="yhbF" /locus_tag="BSU_08960" /old_locus_tag="BSU08960" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 12562816, 20617312; Product type cp:cell process" /codon_start=1 /transl_table=11 /product="conserved protein involved in sporulation" /protein_id="NP_388777.2" /db_xref="EnsemblGenomes-Gn:BSU08960" /db_xref="EnsemblGenomes-Tr:CAB12724" /db_xref="SubtiList:BG10803" /db_xref="UniProtKB/Swiss-Prot:P39133" /translation="METTKLGNLKLYGAGHAAGGAYHNVSIKGEGIVGEGLSAVGCRI YGTGLFLGKAETERLRVLGESECKGDLTAGKINIYGTMKVSGSLQFDRFNLKGQTEIG GNMTGESCDVKGKLSVIGDCETEMFHVTGCVDVSGLLNSGEIKLGLSHDISHVQEIGG TTITVKRRASFFSRKKGKLIADVIEGDRVYLENTEAAVVRGKEVIIGPGCSIGTIEYE YKCECDPHSQIKEKTKL*" gene 972099..972806 /gene="yhbF" /locus_tag="BSU_08960" /old_locus_tag="BSU08960" downshifts 972690 /Source="Nicolas_upshifts" /id="D459" /incds=1 /nref=1 /ntot=127 /MaxReadThrough="4.34704" /MaxDrop="2.64409" /score="45.497414" /energy="-15.3" /TU="U698" /idTUdmin="U698" /TUdmin="-110" /isTUend="FALSE" downshifts 972734 /Source="Nicolas_upshifts" /id="D460" /incds=1 /nref=2 /ntot=35 /MaxReadThrough="4.02504" /MaxDrop="3.21894" /score="45.497414" /energy="-15.3" /TU="U698" /idTUdmin="U698" /TUdmin="-66" /isTUend="FALSE" downshifts 972800 /Source="Nicolas_upshifts" /id="D461" /incds=0 /nref=2 /ntot=41 /MaxReadThrough="1.06365" /MaxDrop="3.74046" /score="45.497414" /energy="-15.3" /TU="NA" /idTUdmin="U698" /TUdmin=0 /isTUend="TRUE" S_feature complement(972833..973008) /Source="Nicolas_S_feature" /locus_tag="new_972833_973008_c" /HighExp="M9-stat, BC, S4, T0.30H, LoTm, Lbstat, S2, BT, HiOs, Lbtran" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.99846699999999999" /TUshortSig="SigA" /TUshortPSig="0.998" /TUlongSig="NA" /TUlongPSig="NA" /label="S313" downshifts complement(972876) /Source="Nicolas_upshifts" /id="D462" /incds=0 /nref=63 /ntot=220 /MaxReadThrough="3.38525" /MaxDrop="4.33005" /score="18.2489321" /energy="-13.5" /TU="U699" /idTUdmin="U699" /TUdmin="-198" /isTUend="FALSE" promotor_-10 complement(973000..973019) /Source="Nicolas_upshift_promotors" /id="U699" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.653346653346653" /psig="0.998001998001998" /xcortree=456 /SigmaFactorBS="tttcttaaaaataaagatactcatacaTCGTTGACaaggcag actgcgaCCGTTCATAATAAAGAAAAAtacagaatcatccagactcggacagcacgga a" /listShort="S313" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(973008) /Source="Nicolas_upshifts" /id="U699" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.653346653346653" /psig="0.998001998001998" /xcortree=456 /SigmaFactorBS="tttcttaaaaataaagatactcatacaTCGTTGACaaggcag actgcgaCCGTTCATAATAAAGAAAAAtacagaatcatccagactcggacagcacgga a" /listShort="S313" /GFF_Attribute="listLong" promotor_-35 complement(973034..973041) /Source="Nicolas_upshift_promotors" /id="U699" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.653346653346653" /psig="0.998001998001998" /xcortree=456 /SigmaFactorBS="tttcttaaaaataaagatactcatacaTCGTTGACaaggcag actgcgaCCGTTCATAATAAAGAAAAAtacagaatcatccagactcggacagcacgga a" /listShort="S313" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 973073..973078 /Source="Nicolas_upshift_promotors" /id="U700" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1094 /SigmaFactorBS="gtcaacgatgtatgagtatctttatttttaagaaaccaaAGC ATGtatcacgagatggcgGCATAGATTGTATCAAAGTaccttatttgcatagtgtatc a" /listShort="prkA, S314, yhbH" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 973094..973112 /Source="Nicolas_upshift_promotors" /id="U700" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1094 /SigmaFactorBS="gtcaacgatgtatgagtatctttatttttaagaaaccaaAGC ATGtatcacgagatggcgGCATAGATTGTATCAAAGTaccttatttgcatagtgtatc a" /listShort="prkA, S314, yhbH" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 973094 /Source="Nicolas_upshifts" /id="U700" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1094 /SigmaFactorBS="gtcaacgatgtatgagtatctttatttttaagaaaccaaAGC ATGtatcacgagatggcgGCATAGATTGTATCAAAGTaccttatttgcatagtgtatc a" /listShort="prkA, S314, yhbH" /GFF_Attribute="listLong" CDS 973156..975051 /gene="prkA" /locus_tag="BSU_08970" /old_locus_tag="BSU08970" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:8626065, 12662922, 25983726, 27806131" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8626065, 12662922, 25983726, 27806131; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="serine protein kinase (involved in sporulation)" /protein_id="NP_388778.1" /db_xref="EnsemblGenomes-Gn:BSU08970" /db_xref="EnsemblGenomes-Tr:CAB12725" /db_xref="GOA:P39134" /db_xref="InterPro:IPR010650" /db_xref="InterPro:IPR013153" /db_xref="InterPro:IPR016230" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG10804" /db_xref="UniProtKB/Swiss-Prot:P39134" /translation="MDILKKIEKYREEEQRLKWEGTFADYLEIIKENPMVAQSAHSRV FNMIKDSGIEEIDGRKKYSFFDRELFGLEESLERLVEEYFHPAAKRLDVRKRILLLMG PVSGGKSTLVTMLKKGLEAYTLTDNGAVYAIKGCPMHEDPLHLIPHHLRDDFYREYGI RIEGSLSPLNVMRLEEEYGGRIEDVKVERIFFSEDKRTGIGTFSPSDPKSQDIADLTG SIDFSTIAEYGSESDPRAYRFDGELNKANRGMMEFQEMLKCDEKFLWHLLSLTQEGNF KAGRFALISADELIVAHTNETEYRSFISNKKNEALHSRIIVMPVPYNLKVSEEERIYE KMIAESDVADVHIAPHTLKVAAMFSILTRLKEPKRSDIDLVKKMRLYDGESVEGYNSV DVEDMKKEYNDEGMSGIDPRYVINRISSTIIRKNMESINSLDVLRSLKEGLDQHPSIS SEDRERYLNFISAARKEYDDIAKKEVQKAFVYSYEESAKTLMDNYLDNVEAYCNKNKL RDPLTGEEMNPDEKLMRSIEEQIGISENAKKAFREEILIRISAYARKGKRFDYNSHER LREAIQKKLFADLKDVVKITTSTKTPDEQQLKKVNEVVARLIDEHGYNSTSANELLKY VGSLLNR*" gene 973156..975051 /gene="prkA" /locus_tag="BSU_08970" /old_locus_tag="BSU08970" promotor_no_box 973598..973698 /Source="Nicolas_upshift_promotors" /id="U701" /multdbtbs="-" /comp="M3" /sig="Sig-" /pcomp="0.31968031968032" /psig="0.31968031968032" /xcortree=684 /SigmaFactorBS="atcatttacgcgatgacttttacagagaatacggcattagaa tagaaggaagtctttctcctttaaatgtcatgaggctggaggaagagtacggaggaag a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_no_box" upshifts 973658 /Source="Nicolas_upshifts" /id="U701" /multdbtbs="-" /comp="M3" /sig="Sig-" /pcomp="0.31968031968032" /psig="0.31968031968032" /xcortree=684 /SigmaFactorBS="atcatttacgcgatgacttttacagagaatacggcattagaa tagaaggaagtctttctcctttaaatgtcatgaggctggaggaagagtacggaggaag a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" downshifts 973724 /Source="Nicolas_upshifts" /id="D463" /incds=1 /nref=5 /ntot=18 /MaxReadThrough="7.33384" /MaxDrop="5.65132" /score="45.497414" /energy="-15.3" /TU="U700" /idTUdmin="U701" /TUdmin=0 /isTUend="TRUE" downshifts 975044 /Source="Nicolas_upshifts" /id="D464" /incds=0 /nref=11 /ntot=57 /MaxReadThrough="6.19375" /MaxDrop="4.381" /score="-0.497429548" /energy="-10.6" /TU="U700" /idTUdmin="U703" /TUdmin="-528" /isTUend="FALSE" promotor_-35 975108..975113 /Source="Nicolas_upshift_promotors" /id="U702" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp="0.971028971028971" /psig="0.971028971028971" /xcortree=1058 /SigmaFactorBS="agggcgggttattttgtcccattttctaaatagtttGTCAAT taaacgtgcatatgtGCATATGATGAATATAAATcttttcaaaagacttgtttcataa t" /listShort="S314, yhbH" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 975129..975147 /Source="Nicolas_upshift_promotors" /id="U702" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp="0.971028971028971" /psig="0.971028971028971" /xcortree=1058 /SigmaFactorBS="agggcgggttattttgtcccattttctaaatagtttGTCAAT taaacgtgcatatgtGCATATGATGAATATAAATcttttcaaaagacttgtttcataa t" /listShort="S314, yhbH" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 975132..975230 /Source="Nicolas_S_feature" /locus_tag="new_975132_975230" /HighExp="S6, S7, S5, S8, S4, S3, BT, LoTm, B36, Pyr" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigEF, SigEF" /TUshortPSig="0.971, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S314" upshifts 975132 /Source="Nicolas_upshifts" /id="U702" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp="0.971028971028971" /psig="0.971028971028971" /xcortree=1058 /SigmaFactorBS="agggcgggttattttgtcccattttctaaatagtttGTCAAT taaacgtgcatatgtGCATATGATGAATATAAATcttttcaaaagacttgtttcataa t" /listShort="S314, yhbH" /GFF_Attribute="listLong" CDS 975231..976409 /gene="yhbH" /locus_tag="BSU_08980" /old_locus_tag="BSU08980" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:11988534, 12662922, 14523133, 25983726" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11988534, 12662922, 14523133, 25983726; Product type f: factor" /codon_start=1 /transl_table=11 /product="factor involved in shape determination" /protein_id="NP_388779.1" /db_xref="EnsemblGenomes-Gn:BSU08980" /db_xref="EnsemblGenomes-Tr:CAB12726" /db_xref="InterPro:IPR006698" /db_xref="InterPro:IPR014230" /db_xref="SubtiList:BG11238" /db_xref="UniProtKB/Swiss-Prot:P45742" /translation="MSQNDSGHFLISEENWSLHRKGFDDQQRHQKKVQEAIKNNLPDL VTEESIIMSNGKDVVKIPIRSLDEYKIRYNYDKNKHVGQGDGESQVGDVVARDGSDKK QGPGKGQGAGDQAGEDYYEAEVSLMDLEEALFKELELPNLQQKERDNIIHTDIEFNDI RKTGLTGNIDKKRTMMSAFKRNAMSGKPSFYPIYPEDLKYKTWNDITKPESKAVVLAM MDTSGSMGVWEKYMARSFFFWMTRFLRTKYETVEIEFIAHHTEARVVSEEDFFSKGES GGTICSSVYRKSLELIDEKYNPARYNIYPFHFSDGDNLTSDNARCVKLVNDIMKKANL FCYGEVNQYNRHSTLMSAYKNVKDEKFKYYILKQKSDVFQALKNFFRNEESGVSHQFS *" gene 975231..976409 /gene="yhbH" /locus_tag="BSU_08980" /old_locus_tag="BSU08980" promotor_-35 975429..975432 /Source="Nicolas_upshift_promotors" /id="U703" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.367632367632368" /psig="0.985014985014985" /xcortree=615 /SigmaFactorBS="atggaaaagatgtagtgaagatcccaatccgttcacttGATG agtataaaatccgtTATAACTATGATAAAAATAAacatgtagggcaaggagacggcga g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 975447..975466 /Source="Nicolas_upshift_promotors" /id="U703" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.367632367632368" /psig="0.985014985014985" /xcortree=615 /SigmaFactorBS="atggaaaagatgtagtgaagatcccaatccgttcacttGATG agtataaaatccgtTATAACTATGATAAAAATAAacatgtagggcaaggagacggcga g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 975451 /Source="Nicolas_upshifts" /id="U703" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.367632367632368" /psig="0.985014985014985" /xcortree=615 /SigmaFactorBS="atggaaaagatgtagtgaagatcccaatccgttcacttGATG agtataaaatccgtTATAACTATGATAAAAATAAacatgtagggcaaggagacggcga g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" downshifts complement(975692) /Source="Nicolas_upshifts" /id="D465" /incds=1 /nref=1 /ntot=23 /MaxReadThrough="2.79078" /MaxDrop="2.94521" /score="-7.1109433" /energy="-11.2" /TU="NA" /idTUdmin="U699" /TUdmin="-3014" /isTUend="FALSE" downshifts 976388 /Source="Nicolas_upshifts" /id="D466" /incds=0 /nref=63 /ntot=180 /MaxReadThrough="1.86673" /MaxDrop="8.19565" /score="27.3980811" /energy="-5.6" /TU="NA" /idTUdmin="U702" /TUdmin=2 /isTUend="TRUE" promotor_-35 976496..976503 /Source="Nicolas_upshift_promotors" /id="U704" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.754245754245754" /psig="0.996003996003996" /xcortree=2450 /SigmaFactorBS="cgcttgcgaaaaaaatacgggagaaaaagaaatttttcCTTT GACAaatcttctttcattTATTAATATTTTATCTTGTGaactattattgaggaatgag g" /listShort="yhbI, yhbJ, yhcA, yhcB, yhcC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 976518..976537 /Source="Nicolas_upshift_promotors" /id="U704" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.754245754245754" /psig="0.996003996003996" /xcortree=2450 /SigmaFactorBS="cgcttgcgaaaaaaatacgggagaaaaagaaatttttcCTTT GACAaatcttctttcattTATTAATATTTTATCTTGTGaactattattgaggaatgag g" /listShort="yhbI, yhbJ, yhcA, yhcB, yhcC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 976518 /Source="Nicolas_upshifts" /id="U704" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.754245754245754" /psig="0.996003996003996" /xcortree=2450 /SigmaFactorBS="cgcttgcgaaaaaaatacgggagaaaaagaaatttttcCTTT GACAaatcttctttcattTATTAATATTTTATCTTGTGaactattattgaggaatgag g" /listShort="yhbI, yhbJ, yhcA, yhcB, yhcC" /GFF_Attribute="listLong" CDS 976569..977033 /gene="yhbI" /locus_tag="BSU_08990" /old_locus_tag="BSU08990" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 20011599; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative transcriptional regulator (MarR family)induced by acid stress" /protein_id="NP_388780.1" /db_xref="EnsemblGenomes-Gn:BSU08990" /db_xref="EnsemblGenomes-Tr:CAB12727" /db_xref="GOA:O31592" /db_xref="InterPro:IPR000835" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG13003" /db_xref="UniProtKB/Swiss-Prot:O31592" /translation="MTESERALLTFEQLFDTSRAIYKKQKKILEIVLEPFDITVLQYL LMFKIHQSGSTPLSKLAMSLDLKPASVTRMTDILYKRQLMNRYDSPDDRRIVMIQLTE EGEELIEKAAVQYAKMGAGLYQKLDTSQLQYLRKLAGSLTKLAEGCSEKSGN*" gene 976569..977033 /gene="yhbI" /locus_tag="BSU_08990" /old_locus_tag="BSU08990" promotor_-35 976858..976864 /Source="Nicolas_upshift_promotors" /id="U705" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.94005994005994" /psig="0.94005994005994" /xcortree=270 /SigmaFactorBS="cagtccggatgaccgccgtatcgtcaTGATTCAgttaaccga agaggGGGAAGAACTGATAGAAAAagccgctgtgcaatatgcaaaaatgggtgctggc t" /listShort="yhbJ, yhcA, yhcB, yhcC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 976879..976897 /Source="Nicolas_upshift_promotors" /id="U705" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.94005994005994" /psig="0.94005994005994" /xcortree=270 /SigmaFactorBS="cagtccggatgaccgccgtatcgtcaTGATTCAgttaaccga agaggGGGAAGAACTGATAGAAAAagccgctgtgcaatatgcaaaaatgggtgctggc t" /listShort="yhbJ, yhcA, yhcB, yhcC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 976892 /Source="Nicolas_upshifts" /id="U705" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.94005994005994" /psig="0.94005994005994" /xcortree=270 /SigmaFactorBS="cagtccggatgaccgccgtatcgtcaTGATTCAgttaaccga agaggGGGAAGAACTGATAGAAAAagccgctgtgcaatatgcaaaaatgggtgctggc t" /listShort="yhbJ, yhcA, yhcB, yhcC" /GFF_Attribute="listLong" promotor_-35 977042..977048 /Source="Nicolas_upshift_promotors" /id="U706" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.976023976023976" /psig="0.976023976023976" /xcortree=808 /SigmaFactorBS="gctgttcagaaaaaagcggtaattaaaaacttctCACATATt ttcaccagctttCCGCAAAATGATagaggatgaaacgaaaggagaaaacaaaatgaac a" /listShort="yhbJ, yhcA, yhcB, yhcC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 977062..977073 /Source="Nicolas_upshift_promotors" /id="U706" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.976023976023976" /psig="0.976023976023976" /xcortree=808 /SigmaFactorBS="gctgttcagaaaaaagcggtaattaaaaacttctCACATATt ttcaccagctttCCGCAAAATGATagaggatgaaacgaaaggagaaaacaaaatgaac a" /listShort="yhbJ, yhcA, yhcB, yhcC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 977068 /Source="Nicolas_upshifts" /id="U706" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.976023976023976" /psig="0.976023976023976" /xcortree=808 /SigmaFactorBS="gctgttcagaaaaaagcggtaattaaaaacttctCACATATt ttcaccagctttCCGCAAAATGATagaggatgaaacgaaaggagaaaacaaaatgaac a" /listShort="yhbJ, yhcA, yhcB, yhcC" /GFF_Attribute="listLong" CDS 977069..977734 /gene="yhbJ" /locus_tag="BSU_09000" /old_locus_tag="BSU09000" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406, 20011599; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative membrane fusion protein; putative exporter subunit (benzoate transcriptome)" /protein_id="NP_388781.1" /db_xref="EnsemblGenomes-Gn:BSU09000" /db_xref="EnsemblGenomes-Tr:CAB12728" /db_xref="GOA:O31593" /db_xref="InterPro:IPR011053" /db_xref="SubtiList:BG13004" /db_xref="UniProtKB/Swiss-Prot:O31593" /translation="MIEDETKGENKMNRGRLILTNIIGLIVVLAIIAGGAYYYYQSTN YVKTDEAKVAGDMAAITAPAAGKVSDWDLDEGKTVKKGDTVAKIKGEQTVDVKSIMDG TIVKNEVKNGQTVQAGTTIAQTIDMDNLYITANIKETDIADIEVGNSVDVVVDGDPDT TFDGTVEEIGYATNSTFDMLPSTNSSGNYTKVTQKVPVKISIKNPSDKVLPGMNASVK ISE*" gene 977069..977734 /gene="yhbJ" /locus_tag="BSU_09000" /old_locus_tag="BSU09000" CDS 977775..979373 /gene="yhcA" /locus_tag="BSU_09010" /old_locus_tag="BSU09010" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406, 20011599; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative exporter (benzoate transcriptome)" /protein_id="NP_388782.1" /db_xref="EnsemblGenomes-Gn:BSU09010" /db_xref="EnsemblGenomes-Tr:CAB12729" /db_xref="GOA:P54585" /db_xref="InterPro:IPR004638" /db_xref="InterPro:IPR011701" /db_xref="InterPro:IPR020846" /db_xref="InterPro:IPR036259" /db_xref="SubtiList:BG11579" /db_xref="UniProtKB/Swiss-Prot:P54585" /translation="MATGKEKNAKNPMSLLIVLMAGLFLAILNQTLLNVAMPHLMTEF GVSATTIQWLTTGYMLVNGVLIPLSAFLITRFGQRSLFLVAMFCFTLGTLVCGIAPNF STMLIGRLIQAVGGGILQPLVMTTILLIFPPESRGKGMGIFGLAMMFAPAVGPTLSGW IIEHYTWRIMFYGLVPIGAIVIIVAFFIFKNMVEPQKIKLDTLGAILSIVGFASLLYG VSEAGSDGWTDPIVLSTVIIGAIAIVAFVVQQLRHDDPMLDFRVFKYDIFSLSSVINI IITVALYTGMFLLPIYLQNLVGFTALQSGLLLLPGAIVMLIMSPISGILFDKFGPRPL AIIGLLVTVVTTYQYTQLTIDTPYTHIMLIYSIRAFGMSLLMMPVMTAGMNQLPARLN SHGTAMSNTLRQISGSIGTSLITTIYTNRTTFHYSQIADKTSTADPNFLHAFQNAVSN LMVNMNVSYDTAKTYVYSHIYKHASLDSNVMGINDAFMWATLFCVAGLILSIFLRDVR KDKLRKKKKEELSLLPAPKEAKES*" gene 977775..979373 /gene="yhcA" /locus_tag="BSU_09010" /old_locus_tag="BSU09010" CDS 979396..979926 /gene="yhcB" /locus_tag="BSU_09020" /old_locus_tag="BSU09020" /EC_number="1.6.5.-" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 15754243, 18041955, 17951395, 19665595, 20011599; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="NADH:quinone oxidoreductase associated to benzoate stress" /protein_id="NP_388783.1" /db_xref="EnsemblGenomes-Gn:BSU09020" /db_xref="EnsemblGenomes-Tr:CAB12730" /db_xref="GOA:P54586" /db_xref="InterPro:IPR005025" /db_xref="InterPro:IPR008254" /db_xref="InterPro:IPR029039" /db_xref="SubtiList:BG11580" /db_xref="UniProtKB/Swiss-Prot:P54586" /translation="MKIYVVYDSEGEHTKVLAEAIAEGARENDAAEVFIDHVDQADIR KLKDMDAIIWGCPGHFGTISSGLKTWIDRLGYLWAEGELINKVGAVFCTTATTHGGLE MTMHNLITPMFHQGMIVVGLPGNVPENALYGSYYGAGVTCPVDSDELMSEEGIQLGRA LGRRVSQVTGNLTAGQ*" gene 979396..979926 /gene="yhcB" /locus_tag="BSU_09020" /old_locus_tag="BSU09020" CDS 979939..980313 /gene="yhcC" /locus_tag="BSU_09030" /old_locus_tag="BSU09030" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical membrane protein" /protein_id="NP_388784.1" /db_xref="EnsemblGenomes-Gn:BSU09030" /db_xref="EnsemblGenomes-Tr:CAB12731" /db_xref="GOA:P54587" /db_xref="SubtiList:BG11581" /db_xref="UniProtKB/Swiss-Prot:P54587" /translation="MAIIIAIIAAVIVIAALITFNVRNASPGPEKQEATDRIAPPEEE KNEAHYPAEARAAEHTPSVVKNDSPKEKRDTMGDDIYRQALQKFKHSDEVHAEEEVTE ESDKMQDRSYRDALLSMKNKKK*" gene 979939..980313 /gene="yhcC" /locus_tag="BSU_09030" /old_locus_tag="BSU09030" downshifts 980302 /Source="Nicolas_upshifts" /id="D467" /incds=0 /nref=32 /ntot=145 /MaxReadThrough="1.78742" /MaxDrop="5.9171" /score="13.777309" /energy="-14.4" /TU="NA" /idTUdmin="U704" /TUdmin=0 /isTUend="TRUE" CDS 980313..980468 /gene="yhcD" /locus_tag="BSU_09040" /old_locus_tag="BSU09040" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="NP_388785.1" /db_xref="EnsemblGenomes-Gn:BSU09040" /db_xref="EnsemblGenomes-Tr:CAB12732" /db_xref="SubtiList:BG11582" /db_xref="UniProtKB/Swiss-Prot:P54588" /translation="MKKANPFTHAGLPFLLFPSIMFLSNKSMEYVVFHLDLVYYVTHT PRIFSGR*" gene 980313..980468 /gene="yhcD" /locus_tag="BSU_09040" /old_locus_tag="BSU09040" promotor_-35 980403..980409 /Source="Nicolas_upshift_promotors" /id="U707" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.571428571428571" /psig=1 /xcortree=2541 /SigmaFactorBS="tgtttttatcaaataaatccatggaatatGTTGTATtccacc ttgatctaGTGTACTATGTTACTCATACaccgaggattttttccgggaggtaaagaca t" /listShort="yhcE, yhcF, yhcG, yhcH, yhcI" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 980424..980443 /Source="Nicolas_upshift_promotors" /id="U707" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.571428571428571" /psig=1 /xcortree=2541 /SigmaFactorBS="tgtttttatcaaataaatccatggaatatGTTGTATtccacc ttgatctaGTGTACTATGTTACTCATACaccgaggattttttccgggaggtaaagaca t" /listShort="yhcE, yhcF, yhcG, yhcH, yhcI" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 980434 /Source="Nicolas_upshifts" /id="U707" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.571428571428571" /psig=1 /xcortree=2541 /SigmaFactorBS="tgtttttatcaaataaatccatggaatatGTTGTATtccacc ttgatctaGTGTACTATGTTACTCATACaccgaggattttttccgggaggtaaagaca t" /listShort="yhcE, yhcF, yhcG, yhcH, yhcI" /GFF_Attribute="listLong" CDS 980473..981234 /gene="yhcE" /locus_tag="BSU_09050" /old_locus_tag="BSU09050" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative integral inner membrane orphan protein" /protein_id="NP_388786.1" /db_xref="EnsemblGenomes-Gn:BSU09050" /db_xref="EnsemblGenomes-Tr:CAB12733" /db_xref="GOA:P54589" /db_xref="SubtiList:BG11583" /db_xref="UniProtKB/Swiss-Prot:P54589" /translation="MNSFLGLLKKDIKLSRMWLLVWICGIIFLLGTGHIIASRTKEPL VIFGFFVAVAFFLLFLSPVFVFYHLRKEGKSQLWLYNPNGGLWLFSSKLAASLLYQFV IQLALTAYGIWMYHMLSVKNLLEHQVDITSTVALLNMYGLISSLDMSVTVIVFWTVFH SLRNWRGMRWAAMVLLVAMWLFFDEYIISPLVESQKHFWPVTVYCNFDFHFHNVWRLE LKPIHLSVLGFPIAIVITFLLLIMASKLLDRKVEV*" gene 980473..981234 /gene="yhcE" /locus_tag="BSU_09050" /old_locus_tag="BSU09050" promotor_-10 complement(980786..980804) /Source="Nicolas_upshift_promotors" /id="U708" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1187 /SigmaFactorBS="tatcaacttgatgctccagcagattttttacagagAGCATAt gatacatccatatgCCATAGGCTGTTAATGCCAactgaatcacaaattgatagagcaa a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(980800) /Source="Nicolas_upshifts" /id="U708" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1187 /SigmaFactorBS="tatcaacttgatgctccagcagattttttacagagAGCATAt gatacatccatatgCCATAGGCTGTTAATGCCAactgaatcacaaattgatagagcaa a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(980820..980825) /Source="Nicolas_upshift_promotors" /id="U708" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1187 /SigmaFactorBS="tatcaacttgatgctccagcagattttttacagagAGCATAt gatacatccatatgCCATAGGCTGTTAATGCCAactgaatcacaaattgatagagcaa a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" CDS 981237..981602 /gene="yhcF" /locus_tag="BSU_09060" /old_locus_tag="BSU09060" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative transcriptional regulator (GntR family)" /protein_id="NP_388787.1" /db_xref="EnsemblGenomes-Gn:BSU09060" /db_xref="EnsemblGenomes-Tr:CAB12734" /db_xref="GOA:P54590" /db_xref="InterPro:IPR000524" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG11584" /db_xref="UniProtKB/Swiss-Prot:P54590" /translation="MDNQFQSSKPIYLQIADQIFYRLVRKELLPGDKLPSVREMAIQT KVNPNTIQRTYSEMERLGIVETRRGQGTFIAEKAEIVDELKDKLTREVLEGFVKQMKE LGLTKEEMLEGIKTFTEGG*" gene 981237..981602 /gene="yhcF" /locus_tag="BSU_09060" /old_locus_tag="BSU09060" CDS 981604..982302 /gene="yhcG" /locus_tag="BSU_09070" /old_locus_tag="BSU09070" /function="16.1: Circulate" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15870467; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative ABC transporter ATP-binding protein" /protein_id="NP_388788.1" /db_xref="EnsemblGenomes-Gn:BSU09070" /db_xref="EnsemblGenomes-Tr:CAB12735" /db_xref="GOA:P54591" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG11585" /db_xref="UniProtKB/Swiss-Prot:P54591" /translation="MEIKLEHVSKKYGRHTAVNDVSITLSSGRIYGLIGPNGSGKSTT LKMMAGLLFPTSGFVKVDEEQVTREMVRQTAYLTELDMFYPHFTVKDMVNFYQSQFPD FHTEQVYKLLNEMQLNPEKKIKKLSKGNRGRLKIVLALARRADVILLDEPFSGLDPMV RDSIVNSLVSYIDFEQQIVVIATHEIDEIETLLDEVIILANGEKVAQREVEDIREQEG MSVLQWFKSKMEVC*" gene 981604..982302 /gene="yhcG" /locus_tag="BSU_09070" /old_locus_tag="BSU09070" CDS 982319..983236 /gene="yhcH" /locus_tag="BSU_09080" /old_locus_tag="BSU09080" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 7476193, 15870467; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative ABC transporter (ATP-binding protein)" /protein_id="NP_388789.1" /db_xref="EnsemblGenomes-Gn:BSU09080" /db_xref="EnsemblGenomes-Tr:CAB12736" /db_xref="GOA:P54592" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR017871" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG11586" /db_xref="UniProtKB/Swiss-Prot:P54592" /translation="MKTVLELKNVTKNIRGRTIIDDLSFTIREGEVFGFLGPNGAGKT TTIRMMVGLMKLSKGDVLICGQSITKEYAKAIKHIGAIVENPELYKFLSGYKNLQQFA RMVKGVTKEKIDEVVELVGLTDRIHDKVKTYSLGMRQRLGLAQCLLHDPKVLILDEPT NGLDPAGIREIRDHLKKLTRERGMAVIVSSHLLSEMELMCDRIAILQKGKLIDIQNVK DENIDENDTYFFQVEQPSEAATVLNQYDLLSKTNGVEIKLAKEEVPAVIELLVMQQIR IYEVKVITKSLEDRFLEMTGETKEEVQHA*" gene 982319..983236 /gene="yhcH" /locus_tag="BSU_09080" /old_locus_tag="BSU09080" CDS 983229..984170 /gene="yhcI" /locus_tag="BSU_09090" /old_locus_tag="BSU09090" /function="16.1: Circulate" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 15870467, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative ABC transporter (permease)" /protein_id="NP_388790.1" /db_xref="EnsemblGenomes-Gn:BSU09090" /db_xref="EnsemblGenomes-Tr:CAB12737" /db_xref="GOA:P54593" /db_xref="InterPro:IPR032688" /db_xref="SubtiList:BG11587" /db_xref="UniProtKB/Swiss-Prot:P54593" /translation="MLNLIYNEWLKIFSRAGTWVMIGILGLTMVGFAFLANHFSAGES NSHWKQELQAQNAELKKEIKEDPSLKDGYKETITLNDYRIEHNIPSDTGYTVWSYVTD SANFTILTGLFTIIIAAGIVANEFNWGTIKLLMIRPLSRFQILMSKYITVLLFGLLLL LILFIGSTLLGLIFFGTGGETAANIHLIYKDGHVIEQNMMGHLATTYLSESVSALMVA TMAFMLSAVFRNSSLAVGFSIFLLVAGTTATAFIAAKFDWAKYILFANVDLTQYVDGT PLIKGMTMTFSLVMLAIYFIIFLLLAFGIFMKRDIAN*" gene 983229..984170 /gene="yhcI" /locus_tag="BSU_09090" /old_locus_tag="BSU09090" downshifts 984152 /Source="Nicolas_upshifts" /id="D468" /incds=0 /nref=43 /ntot=186 /MaxReadThrough="2.67567" /MaxDrop="4.46232" /score="20.0218504" /energy="-13.6" /TU="NA" /idTUdmin="U707" /TUdmin=0 /isTUend="TRUE" CDS complement(984262..984465) /gene="cspB" /locus_tag="BSU_09100" /old_locus_tag="BSU09100" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:12493834, 16352840, 22128343, 25851716" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12493834, 16352840, 22128343, 25851716; Product type f: factor" /codon_start=1 /transl_table=11 /product="major cold-shock protein, RNA helicase co-factor, RNA co-chaperone" /protein_id="NP_388791.1" /db_xref="EnsemblGenomes-Gn:BSU09100" /db_xref="EnsemblGenomes-Tr:CAB12738" /db_xref="GOA:P32081" /db_xref="InterPro:IPR002059" /db_xref="InterPro:IPR011129" /db_xref="InterPro:IPR012156" /db_xref="InterPro:IPR012340" /db_xref="InterPro:IPR019844" /db_xref="PDB:1CSP" /db_xref="PDB:1CSQ" /db_xref="PDB:1NMF" /db_xref="PDB:1NMG" /db_xref="PDB:2ES2" /db_xref="PDB:2F52" /db_xref="PDB:2I5L" /db_xref="PDB:2I5M" /db_xref="PDB:3PF4" /db_xref="PDB:3PF5" /db_xref="SubtiList:BG10824" /db_xref="UniProtKB/Swiss-Prot:P32081" /translation="MLEGKVKWFNSEKGFGFIEVEGQDDVFVHFSAIQGEGFKTLEEG QAVSFEIVEGNRGPQAANVTKEA*" gene complement(984262..984465) /gene="cspB" /locus_tag="BSU_09100" /old_locus_tag="BSU09100" downshifts complement(984276) /Source="Nicolas_upshifts" /id="D469" /incds=0 /nref=169 /ntot=281 /MaxReadThrough="5.28215" /MaxDrop="9.14889" /score="33.2405587" /energy="-13.1" /TU="U710" /idTUdmin="U710" /TUdmin="-48" /isTUend="FALSE" S_feature complement(984466..984593) /Source="Nicolas_S_feature" /locus_tag="new_984466_984593_c" /HighExp="BC, C90, GM 15, BI, T-1.10H, UNK1, S1, Sw, nit, G/S" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="SigA" /TUlongPSig="0.999" /label="S315" misc_feature 984553..984564 /Source="Nicolas_upshift_promotors" /id="U709" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.618381618381618" /psig="0.098901098901099" /xcortree=713 /SigmaFactorBS="ttgctcttaacaaactttcaagacgaaaactcttacaaaact tTCTTCTTAAAGAtagttcgaacaaaaataattacctttactctaccagtaatcttca g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 984570 /Source="Nicolas_upshifts" /id="U709" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.618381618381618" /psig="0.098901098901099" /xcortree=713 /SigmaFactorBS="ttgctcttaacaaactttcaagacgaaaactcttacaaaact tTCTTCTTAAAGAtagttcgaacaaaaataattacctttactctaccagtaatcttca g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 complement(984582..984601) /Source="Nicolas_upshift_promotors" /id="U710" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.32967032967033" /psig=1 /xcortree=2182 /SigmaFactorBS="tatggtattttccgaaaaaaatttcaataagcaGTTGTTttt tctgaagattACTGGTAGAGTAAAGGTAATtatttttgttcgaactatctttaagaag a" /listShort="S315, cspB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(984593) /Source="Nicolas_upshifts" /id="U710" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.32967032967033" /psig=1 /xcortree=2182 /SigmaFactorBS="tatggtattttccgaaaaaaatttcaataagcaGTTGTTttt tctgaagattACTGGTAGAGTAAAGGTAATtatttttgttcgaactatctttaagaag a" /listShort="S315, cspB" /GFF_Attribute="listLong" S_feature complement(984595..985733) /Source="Nicolas_S_feature" /locus_tag="new_984595_985733_c" /HighExp="C30, G180, G150, Oxctl, G135, Paraq, HPh, LPh, dia0, Lbexp" /AntisenseName="yhcJ" /AntisenseCor="0.25433958616302499" /AntisenseRegPval="-4.5999999999999996" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S316" promotor_-35 complement(984615..984620) /Source="Nicolas_upshift_promotors" /id="U710" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.32967032967033" /psig=1 /xcortree=2182 /SigmaFactorBS="tatggtattttccgaaaaaaatttcaataagcaGTTGTTttt tctgaagattACTGGTAGAGTAAAGGTAATtatttttgttcgaactatctttaagaag a" /listShort="S315, cspB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 984760..984767 /Source="Nicolas_upshift_promotors" /id="U711" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.386613386613387" /psig="0.997002997002997" /xcortree=1871 /SigmaFactorBS="attccttcattttgggaagataagtaataggAATTGACAacc ttattggatatGAGTAAGGTAAAAGTTAATcaatattacaaatgacaacgtttatcaa c" /listShort="S317, yhcJ" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 984782..984800 /Source="Nicolas_upshift_promotors" /id="U711" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.386613386613387" /psig="0.997002997002997" /xcortree=1871 /SigmaFactorBS="attccttcattttgggaagataagtaataggAATTGACAacc ttattggatatGAGTAAGGTAAAAGTTAATcaatattacaaatgacaacgtttatcaa c" /listShort="S317, yhcJ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 984789 /Source="Nicolas_upshifts" /id="U711" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.386613386613387" /psig="0.997002997002997" /xcortree=1871 /SigmaFactorBS="attccttcattttgggaagataagtaataggAATTGACAacc ttattggatatGAGTAAGGTAAAAGTTAATcaatattacaaatgacaacgtttatcaa c" /listShort="S317, yhcJ" /GFF_Attribute="listLong" S_feature 984790..984900 /Source="Nicolas_S_feature" /locus_tag="new_984790_984900" /HighExp="Diami, dia15, dia5, H2O2, Salt, C90, Paraq, UNK1, T-4.40H, nit" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.997" /TUlongSig="NA" /TUlongPSig="NA" /label="S317" CDS 984901..985731 /gene="yhcJ" /locus_tag="BSU_09110" /old_locus_tag="BSU09110" /function="7: Transport and binding proteins" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type lp: lipoprotein" /codon_start=1 /transl_table=11 /product="putative ABC transporter (binding lipoprotein)" /protein_id="NP_388792.2" /db_xref="EnsemblGenomes-Gn:BSU09110" /db_xref="EnsemblGenomes-Tr:CAB12739" /db_xref="GOA:P54594" /db_xref="InterPro:IPR004872" /db_xref="SubtiList:BG11588" /db_xref="UniProtKB/Swiss-Prot:P54594" /translation="MKKWLICSFVLVLLVSFTACSPSAEHESIKIGIAESDGAIWNYI AQKAEEAGLDIQLIPFSDYAESDIALANKEIDANAFQTISYFQSFTEKYKLNLAPLGT TYITPMGIYSKRYERIRDISRGAVVSVPDKAFDFGRALTVLQEAGLLTLKNGFNGTGS VDMIKDNPRHLKLKAVRQQDAVSGADVFVMKPSEAKKAGLNPKKHTLKSGGLMSEEEM NLIVVRAEDQDREALQTILELYQADDTAAFIEKEYQGDLVPAFLPLKRLSDWKNEFEH *" gene 984901..985731 /gene="yhcJ" /locus_tag="BSU_09110" /old_locus_tag="BSU09110" downshifts 985690 /Source="Nicolas_upshifts" /id="D470" /incds=0 /nref=38 /ntot=203 /MaxReadThrough="2.83059" /MaxDrop="3.90173" /score="-4.94928928" /energy="-7.3" /TU="NA" /idTUdmin="U711" /TUdmin="-3" /isTUend="TRUE" CDS complement(985734..986813) /gene="dgcK" /locus_tag="BSU_09120" /old_locus_tag="BSU09120" /EC_number="2.7.7.65" /function="16.3: Control" /function="16.1: Circulate" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:23893111" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 23893111; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="diguanylate cyclase" /protein_id="NP_388793.1" /db_xref="EnsemblGenomes-Gn:BSU09120" /db_xref="EnsemblGenomes-Tr:CAB12740" /db_xref="GOA:P54595" /db_xref="InterPro:IPR000160" /db_xref="InterPro:IPR011620" /db_xref="InterPro:IPR029787" /db_xref="SubtiList:BG11589" /db_xref="UniProtKB/Swiss-Prot:P54595" /translation="MLKELFVNLTILITFNYLFTHLFKERLVHKKDSISFQAVKGLAC GLLGVILMVFGFTYQHSIIDLRNIPIMIAALYGGWVSTATALAMITAGRLLITMNTSA LYSVIIICIAAIPSLIVSRRKKVQLKHAFYLLIITNSLISFSFYFLIDLHSYELHLYF WIISIAGGMLSLYIIDHETNAHLLFKQYKFQAHFDFLTGVYNRRKFEETTKALYQQAA DTPHFQFALIYMDIDHFKTINDQYGHHEGDQVLKELGLRLKQTIRNTDPAARIGGEEF AVLLPNCSLDKAARIAERIRSTVSDAPIVLTNGDELSVTISLGAAHYPNNTEQPGSLP ILADQMLYKAKETGRNRVCFSEKKE*" gene complement(985734..986813) /gene="dgcK" /locus_tag="BSU_09120" /old_locus_tag="BSU09120" promotor_-10 complement(986823..986842) /Source="Nicolas_upshift_promotors" /id="U712" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.988011988011988" /psig="0.999000999001" /xcortree=2608 /SigmaFactorBS="tatcaattcaagtaaaaaaaccttatataatgccttttttgt TCTTTtctttcccttccatcTTTAGTACCTTATATAAGGGtgataatatttgctgaaa g" /listShort="yhcK, S316" /listLong="S315, cspB" /label="promotor_-10" upshifts complement(986844) /Source="Nicolas_upshifts" /id="U712" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.988011988011988" /psig="0.999000999001" /xcortree=2608 /SigmaFactorBS="tatcaattcaagtaaaaaaaccttatataatgccttttttgt TCTTTtctttcccttccatcTTTAGTACCTTATATAAGGGtgataatatttgctgaaa g" /listShort="yhcK, S316" /listLong="S315, cspB" promotor_-35 complement(986858..986862) /Source="Nicolas_upshift_promotors" /id="U712" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.988011988011988" /psig="0.999000999001" /xcortree=2608 /SigmaFactorBS="tatcaattcaagtaaaaaaaccttatataatgccttttttgt TCTTTtctttcccttccatcTTTAGTACCTTATATAAGGGtgataatatttgctgaaa g" /listShort="yhcK, S316" /listLong="S315, cspB" /label="promotor_-35" promotor_-35 986920..986927 /Source="Nicolas_upshift_promotors" /id="U713" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.651348651348651" /psig=1 /xcortree=1745 /SigmaFactorBS="tttttacttgaattgataagttaaaataattcgCACTTGACc catcggaattagTGTAATATAGTAAATGAGAAaatttgaagggagagtttacctgctt t" /listShort="tcyP" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 986941..986960 /Source="Nicolas_upshift_promotors" /id="U713" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.651348651348651" /psig=1 /xcortree=1745 /SigmaFactorBS="tttttacttgaattgataagttaaaataattcgCACTTGACc catcggaattagTGTAATATAGTAAATGAGAAaatttgaagggagagtttacctgctt t" /listShort="tcyP" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 986947 /Source="Nicolas_upshifts" /id="U713" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.651348651348651" /psig=1 /xcortree=1745 /SigmaFactorBS="tttttacttgaattgataagttaaaataattcgCACTTGACc catcggaattagTGTAATATAGTAAATGAGAAaatttgaagggagagtttacctgctt t" /listShort="tcyP" /GFF_Attribute="listLong" CDS 986986..988377 /gene="tcyP" /locus_tag="BSU_09130" /old_locus_tag="BSU09130" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:12193636, 15262924, 15849754, 16513748, 16850406, 19508281" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12193636, 15262924, 15849754, 16513748, 16850406, 19508281; Product type t : transporter" /codon_start=1 /transl_table=11 /product="(sodium)-cystine symporter" /protein_id="NP_388794.1" /db_xref="EnsemblGenomes-Gn:BSU09130" /db_xref="EnsemblGenomes-Tr:CAB12741" /db_xref="GOA:P54596" /db_xref="InterPro:IPR001991" /db_xref="InterPro:IPR036458" /db_xref="SubtiList:BG11590" /db_xref="UniProtKB/Swiss-Prot:P54596" /translation="METLLVVLHVFILFLLILGLFVMQKKHVSFSKRVFTALGLGIVF GFALQLIYGPTSNIVIQTADWFNIAGGGYVKLLQMVVMPLVFISILGAFTKLKLTKNL GKISGLIIGILVATTAVAAAVGIASALSFDLQAIQVDQGSTELSRGQELQQKSEDMTA KTLPQQIVELLPGNPFLDFTGARPTSTIAVVIFAAFLGVAFLGVKHKQPEQAETFKKL VDAVYAIVMRVVTLILRLTPYGVLAIMTKTIATSDLDSILKLGMFVIASYAALITMFI IHLLLLTFSGLNPVIYLKKAVPVLVFAFTSRSSAGALPLNIKTQRSMGVPEGIANFAG SFGLSIGQNGCAGIYPAMLAMMIAPTVGQNPFDPVFIITVIAVVAISSFGVAGVGGGA TFAALLVLSSLNMPVALAGLLISIEPLIDMGRTALNVSGSMTSGLITSKVTKEIDQGA FHDQSRVIEAEEA*" gene 986986..988377 /gene="tcyP" /locus_tag="BSU_09130" /old_locus_tag="BSU09130" S_feature complement(988013..988416) /Source="Nicolas_S_feature" /locus_tag="new_988013_988416_c" /HighExp="S8, S6, Etha, S5, S7, S4, ferm, nit, Salt, S3" /AntisenseName="tcyP" /AntisenseCor="-0.40132140065468203" /AntisenseRegPval="-11.1" /CDS_PredictionProba="NA" /TUshortSig="SigB" /TUshortPSig="0.96" /TUlongSig="NA" /TUlongPSig="NA" /label="S318" downshifts 988356 /Source="Nicolas_upshifts" /id="D471" /incds=0 /nref=58 /ntot=164 /MaxReadThrough="2.37899" /MaxDrop="5.34563" /score="19.9118074" /energy="-12.8" /TU="NA" /idTUdmin="U713" /TUdmin="-21" /isTUend="TRUE" CDS complement(988417..988872) /gene="yhcM" /locus_tag="BSU_09140" /old_locus_tag="BSU09140" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 21625606" /codon_start=1 /transl_table=11 /product="expressed protein of unknown function" /protein_id="NP_388795.1" /db_xref="EnsemblGenomes-Gn:BSU09140" /db_xref="EnsemblGenomes-Tr:CAB12742" /db_xref="SubtiList:BG11591" /db_xref="UniProtKB/Swiss-Prot:P54597" /translation="MLFNQRRGISPAALIIGSTMLITALSPQIRQRISGFITGQMNRR NSENNTFDASNVGNMVKQAFSGSSGSSGDNQDRSQHQSQRQNGRQHQHAGQQQPQHQH TQSQTRQTETAAKKRQPHYAEPIHFEQNAMNVMDDNTMMEMLEDLEPGR*" gene complement(988417..988872) /gene="yhcM" /locus_tag="BSU_09140" /old_locus_tag="BSU09140" promotor_-10 complement(988887..988905) /Source="Nicolas_upshift_promotors" /id="U714" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.96003996003996" /psig="0.96003996003996" /xcortree=733 /SigmaFactorBS="tttaattatgcatgcaaatctggaggaaatgctttcccggga aatataaCGGTTAAtttgtctaacgaggGGGAAAATATGAATACACTgcaaaggaggg a" /listShort="yhcM, S318" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(988915) /Source="Nicolas_upshifts" /id="U714" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.96003996003996" /psig="0.96003996003996" /xcortree=733 /SigmaFactorBS="tttaattatgcatgcaaatctggaggaaatgctttcccggga aatataaCGGTTAAtttgtctaacgaggGGGAAAATATGAATACACTgcaaaggaggg a" /listShort="yhcM, S318" /GFF_Attribute="listLong" promotor_-35 complement(988920..988926) /Source="Nicolas_upshift_promotors" /id="U714" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.96003996003996" /psig="0.96003996003996" /xcortree=733 /SigmaFactorBS="tttaattatgcatgcaaatctggaggaaatgctttcccggga aatataaCGGTTAAtttgtctaacgaggGGGAAAATATGAATACACTgcaaaggaggg a" /listShort="yhcM, S318" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 988964..988970 /Source="Nicolas_upshift_promotors" /id="U715" /multdbtbs="SigF,SigG" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=835 /SigmaFactorBS="tatatttcccgggaaagcatttcctccagatttgcaTGCATA AttaaagccagttaGAAAAACCTATAagtaaagtgataaaggaggaattcacatgttt g" /listShort="yhcN" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 988984..988995 /Source="Nicolas_upshift_promotors" /id="U715" /multdbtbs="SigF,SigG" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=835 /SigmaFactorBS="tatatttcccgggaaagcatttcctccagatttgcaTGCATA AttaaagccagttaGAAAAACCTATAagtaaagtgataaaggaggaattcacatgttt g" /listShort="yhcN" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 988988 /Source="Nicolas_upshifts" /id="U715" /multdbtbs="SigF,SigG" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=835 /SigmaFactorBS="tatatttcccgggaaagcatttcctccagatttgcaTGCATA AttaaagccagttaGAAAAACCTATAagtaaagtgataaaggaggaattcacatgttt g" /listShort="yhcN" /GFF_Attribute="listLong" CDS 989022..989591 /gene="yhcN" /locus_tag="BSU_09150" /old_locus_tag="BSU09150" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 9611260, 28333204; Product type lp: lipoprotein" /codon_start=1 /transl_table=11 /product="putative germination lipoprotein" /protein_id="NP_388796.2" /db_xref="EnsemblGenomes-Gn:BSU09150" /db_xref="EnsemblGenomes-Tr:CAB12743" /db_xref="GOA:P54598" /db_xref="InterPro:IPR014247" /db_xref="InterPro:IPR019076" /db_xref="SubtiList:BG11592" /db_xref="UniProtKB/Swiss-Prot:P54598" /translation="MFGKKQVLASVLLIPLLMTGCGVADQGEGRRDNNDVRNVNYRNP ANDDMRNVNNRDNVDNNVNDNVNNNRVNDDNNNDRKLEVADEAADKVTDLKEVKHADI IVAGNQAYVAVVLTNGNKGAVENNLKKKIAKKVRSTDKNIDNVYVSANPDFVERMQGY GKRIQNGDPIAGLFDEFTQTVQRVFPNAE*" gene 989022..989591 /gene="yhcN" /locus_tag="BSU_09150" /old_locus_tag="BSU09150" promotor_-35 989218..989224 /Source="Nicolas_upshift_promotors" /id="U716" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.634365634365634" /psig="0.634365634365634" /xcortree=783 /SigmaFactorBS="gtaaacaatcgggataacgttgacaacaatgttaatgataat gTCAATAAcaatcgtgtaaatGACGATAATAACaacgaccgaaaacttgaggttgctg a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 989235 /Source="Nicolas_upshifts" /id="U716" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.634365634365634" /psig="0.634365634365634" /xcortree=783 /SigmaFactorBS="gtaaacaatcgggataacgttgacaacaatgttaatgataat gTCAATAAcaatcgtgtaaatGACGATAATAACaacgaccgaaaacttgaggttgctg a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 989238..989249 /Source="Nicolas_upshift_promotors" /id="U716" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.634365634365634" /psig="0.634365634365634" /xcortree=783 /SigmaFactorBS="gtaaacaatcgggataacgttgacaacaatgttaatgataat gTCAATAAcaatcgtgtaaatGACGATAATAACaacgaccgaaaacttgaggttgctg a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" downshifts 989566 /Source="Nicolas_upshifts" /id="D472" /incds=0 /nref=26 /ntot=183 /MaxReadThrough="1.84697" /MaxDrop="7.80159" /score="33.0647397" /energy="-12.9" /TU="NA" /idTUdmin="U715" /TUdmin="-21" /isTUend="TRUE" promotor_-35 989634..989643 /Source="Nicolas_upshift_promotors" /id="U717" /multdbtbs="SigE,SigK" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1355 /SigmaFactorBS="caatttgtgcggctttttctttgcgttAATGACACACtgcga actcaggcTGCATAGAGTAAAAATAAAAaggtacaagacggaccggctcagggaggga g" /listShort="yhcO" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 989657..989676 /Source="Nicolas_upshift_promotors" /id="U717" /multdbtbs="SigE,SigK" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1355 /SigmaFactorBS="caatttgtgcggctttttctttgcgttAATGACACACtgcga actcaggcTGCATAGAGTAAAAATAAAAaggtacaagacggaccggctcagggaggga g" /listShort="yhcO" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 989667 /Source="Nicolas_upshifts" /id="U717" /multdbtbs="SigE,SigK" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1355 /SigmaFactorBS="caatttgtgcggctttttctttgcgttAATGACACACtgcga actcaggcTGCATAGAGTAAAAATAAAAaggtacaagacggaccggctcagggaggga g" /listShort="yhcO" /GFF_Attribute="listLong" CDS 989712..990680 /gene="yhcO" /locus_tag="BSU_09165" /old_locus_tag="BSU09165" /function="18: Unknown function" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="putative exported protein (sporulation germination island)" /protein_id="NP_388797.2" /db_xref="EnsemblGenomes-Gn:BSU09165" /db_xref="EnsemblGenomes-Tr:CAB12744" /db_xref="SubtiList:BG11593" /db_xref="UniProtKB/Swiss-Prot:P54599" /translation="MRDGIGKRAASALFLCGVLVMLAVSSAIVSSAMYILSFPGQASG ITKEQVTKHMKKESFKQADIYYTSKEKSLLPLTKETLEYAVSINQIMIGYSNQKPIDI IFFPNEKQMEAYSGLLDVVGFYSEREQLIGLLPEEKKKLLEGDEVAVYLYQRLLIHEY SHHAFHQKLKELETDPDEFPLWFHEGLSEWIANYELLIDPITFSVVPFDRLQTDRDWQ EARAEYDTDVYLQSFYMIDELTDKYGKDIISEMIKETAKKGDFEKGFKSATKESLDQF EKDFKKKFEKNSAALDSIYPMPLLLVKSLLTHSALCRRHLSLGRGE*" gene 989712..990680 /gene="yhcO" /locus_tag="BSU_09165" /old_locus_tag="BSU09165" downshifts 990556 /Source="Nicolas_upshifts" /id="D473" /incds=1 /nref=28 /ntot=62 /MaxReadThrough="1.51621" /MaxDrop="5.75619" /score="6.21571271" /energy="-16.1" /TU="NA" /idTUdmin="U717" /TUdmin="-1" /isTUend="TRUE" CDS complement(990612..991265) /gene="yhcQ" /locus_tag="BSU_09180" /old_locus_tag="BSU09180" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type s: structure" /codon_start=1 /transl_table=11 /product="putative spore coat protein" /protein_id="NP_388799.1" /db_xref="EnsemblGenomes-Gn:BSU09180" /db_xref="EnsemblGenomes-Tr:CAB12746" /db_xref="GOA:P54601" /db_xref="InterPro:IPR012347" /db_xref="InterPro:IPR012851" /db_xref="SubtiList:BG11595" /db_xref="UniProtKB/Swiss-Prot:P54601" /translation="MDQFNQQQQSQMNKGIPGKPHKNHGGHEMFDMHEVLSGTLTVLD QFMMLRQFCKDQELLNILDRQHQFITSQYNITAECFKTGSEPSQKTATYMMKEDNQTV YGMQPSQPKKPVQSMNDIDDSIISRQMLCAIKAQASMLTMASLEMTNPAVRRVLSAQI QEYVEMAFEIFLYQNKHGYYQVPQLDAQDMEQLRNSFAPAQGQMPPTQGGMGQQGLH* " gene complement(990612..991265) /gene="yhcQ" /locus_tag="BSU_09180" /old_locus_tag="BSU09180" downshifts complement(990629) /Source="Nicolas_upshifts" /id="D474" /incds=0 /nref=15 /ntot=57 /MaxReadThrough="4.13099" /MaxDrop="4.95733" /score="8.67086892" /energy="-12.9" /TU="U718" /idTUdmin="U718" /TUdmin="-546" /isTUend="FALSE" promotor_-10 complement(991296..991307) /Source="Nicolas_upshift_promotors" /id="U718" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=828 /SigmaFactorBS="acagacagcatataattcctttcaggcttcTGCATAAtacac ggcagactgACACAAAATACAgctgatctgaaaaaaaaggaggaattcggtttggatc a" /listShort="yhcQ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(991298) /Source="Nicolas_upshifts" /id="U718" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=828 /SigmaFactorBS="acagacagcatataattcctttcaggcttcTGCATAAtacac ggcagactgACACAAAATACAgctgatctgaaaaaaaaggaggaattcggtttggatc a" /listShort="yhcQ" /GFF_Attribute="listLong" promotor_-35 complement(991322..991328) /Source="Nicolas_upshift_promotors" /id="U718" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=828 /SigmaFactorBS="acagacagcatataattcctttcaggcttcTGCATAAtacac ggcagactgACACAAAATACAgctgatctgaaaaaaaaggaggaattcggtttggatc a" /listShort="yhcQ" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 991337..991345 /Source="Nicolas_upshift_promotors" /id="U719" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp=1 /psig=1 /xcortree=543 /SigmaFactorBS="tctgccgtgtattatgcagaagcctgAAAGGAATTatatgct gtcTGTCGAAATGATAAGCAGAcaaaatcgttgtcattatgtgtataagggaggaaat a" /listShort="yhcR, yhcS" /GFF_Attribute="listLong" /label="promotor_-35" CDS 991348..995001 /gene="mncR" /locus_tag="BSU_09190" /old_locus_tag="BSU09190" /EC_number="3.1.-.-" /function="16.11: Scavenge (Catabolism)" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:15292138, 21800427, 22020651" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15292138, 21800427, 22020651; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="non specific extracellular Ca2+-dependent endonuclease cleaving RNA and DNA" /protein_id="NP_388800.1" /db_xref="EnsemblGenomes-Gn:BSU09190" /db_xref="EnsemblGenomes-Tr:CAB12747" /db_xref="GOA:P54602" /db_xref="InterPro:IPR004843" /db_xref="InterPro:IPR006146" /db_xref="InterPro:IPR006179" /db_xref="InterPro:IPR008334" /db_xref="InterPro:IPR012340" /db_xref="InterPro:IPR016071" /db_xref="InterPro:IPR019948" /db_xref="InterPro:IPR029052" /db_xref="InterPro:IPR035437" /db_xref="InterPro:IPR035451" /db_xref="InterPro:IPR036907" /db_xref="SubtiList:BG11596" /db_xref="UniProtKB/Swiss-Prot:P54602" /translation="MLSVEMISRQNRCHYVYKGGNMMRRILHIVLITALMFLNVMYTF EAVKAAEPQQPISIEKAIQQKEGQALVEGYAVGQAVSPQHYKLTSPFSNDYNVALADR KNKTSPEHILPVQIPSAFRSQFGLQTNPLLLGKKITVQGKLENYFNTTGLKNVQSMNV TDDTKTPPAEQQVTINEARGRLNEEVTIKGIITADQNAIGGGKLSTFLQDETGGINIY SPSPEQFPELKEGMDVTVTGKITSYQGLKEIVPNSSGIKINQSNQSLPAPKHLTINEL INGSLGDQYEGRLVKLTAFVSSIPSSPAGGGYNVTMIDDDHHAMTLRVMNETGVINEL DEGKWYEFTGVLSRYQTFQLLPRKSADLKLLEEQPAPPSAEGEYEGIVDRVVDGDTIH LKSPVLGTTKIRFVNVDAPETYHTPKNDADENQLRFGKKASDYLKTVLSPGDKITVKV GSEAKDSYGRLLGQVITESGSNVNLELVKNGYAPTYFIWPVDNEEDYQQFQAAVAAAK KDQKGIWNENDPLMEMPFEFRAREQGKGLTRYVGDSSNKTYVQPADWKKIAVENRIFF ASASEAESAGYKKRQTAPQEHVPLRILSMNDLHGKIDQQYELDLDGNGTVDGTFGRMD YAAAYLKEKKAEKKNSLIVHAGDMIGGSSPVSSLLQDEPTVELMEDIGFDVGTVGNHE FDEGTDELLRILNGGDHPKGTSGYDGQNFPLVCANCKMKSTGEPFLPAYDIINVEGVP VAFIGVVTQSAAGMVMPEGIKNIEFTDEATAVNKAAEELKKKGVKAIAVLAHMSAEQN GNAITGESADLANKTDSEIDVIFAAHNHQVVNGEVNGKLIVQAFEYGKAIGVVDVEID KTTKDIVKKSAEIVYVDQSKIEPDVSASAILKKYETIAEPIISEVVGEAAVDMEGGYS NDGDTPLGNLIADGMRAAMKTDFALMNGGGIREALKKGPITWGDLYNIQPFGNVLTKL EIKGKDLREIINAQISPVFGPDYSISGFTYTWDKETGKAVDMKMADGTEIQPDATYTL TVNNFMATATGAKYQPIGLLGKNPVTGPEDLEATVEYVKSFDEPIAYTKEGRIKLAEA SDIEDPVTEDPITEEPGDDPGTEDPIKEDPRPGEDLPDIKETPGTAPVHQLPPSAISR FNEIPINNTKTADTANSISTLPLQTETAESGSDHQLPDTSAGYYNFMVIGAAVTLSGT YLYVRRKRSASRT*" gene 991348..995001 /gene="mncR" /locus_tag="BSU_09190" /old_locus_tag="BSU09190" promotor_-10 991356..991374 /Source="Nicolas_upshift_promotors" /id="U719" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp=1 /psig=1 /xcortree=543 /SigmaFactorBS="tctgccgtgtattatgcagaagcctgAAAGGAATTatatgct gtcTGTCGAAATGATAAGCAGAcaaaatcgttgtcattatgtgtataagggaggaaat a" /listShort="yhcR, yhcS" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 991371 /Source="Nicolas_upshifts" /id="U719" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp=1 /psig=1 /xcortree=543 /SigmaFactorBS="tctgccgtgtattatgcagaagcctgAAAGGAATTatatgct gtcTGTCGAAATGATAAGCAGAcaaaatcgttgtcattatgtgtataagggaggaaat a" /listShort="yhcR, yhcS" /GFF_Attribute="listLong" CDS 994998..995594 /gene="srtA" /locus_tag="BSU_09200" /old_locus_tag="BSU09200" /EC_number="3.4.22.70" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:12823805, 21800427, 22020651, 25038633" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12823805, 21800427, 22020651, 25038633; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="sortase A" /protein_id="NP_388801.1" /db_xref="EnsemblGenomes-Gn:BSU09200" /db_xref="EnsemblGenomes-Tr:CAB12748" /db_xref="GOA:P54603" /db_xref="InterPro:IPR005754" /db_xref="InterPro:IPR023365" /db_xref="SubtiList:BG11597" /db_xref="UniProtKB/Swiss-Prot:P54603" /translation="MKKVIPLFIIAAGLVIAGYGGFKLIDTNTKTEQTLKEAKLAAKK PQEASGTKNSTDQAKNKASFKPETGQASGILEIPKINAELPIVEGTDADDLEKGVGHY KDSYYPDENGQIVLSGHRDTVFRRTGELEKGDQLRLLLSYGEFTYEIVKTKIVDKDDT SIITLQHEKEELILTTCYPFSYVGNAPKRYIIYGKRVT*" gene 994998..995594 /gene="srtA" /locus_tag="BSU_09200" /old_locus_tag="BSU09200" downshifts 995573 /Source="Nicolas_upshifts" /id="D475" /incds=0 /nref=142 /ntot=248 /MaxReadThrough="0.9984" /MaxDrop="5.92245" /score="-4.06268332" /energy="-8.8" /TU="NA" /idTUdmin="U719" /TUdmin=0 /isTUend="TRUE" CDS complement(995624..996532) /gene="yhcT" /locus_tag="BSU_09210" /old_locus_tag="BSU09210" /EC_number="5.4.99.-" /function="16.2: Construct biomass (Anabolism)" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 9814761, 15044829; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative RNA pseudouridine synthase" /protein_id="NP_388802.2" /db_xref="EnsemblGenomes-Gn:BSU09210" /db_xref="EnsemblGenomes-Tr:CAB12749" /db_xref="GOA:P54604" /db_xref="InterPro:IPR002942" /db_xref="InterPro:IPR006145" /db_xref="InterPro:IPR006224" /db_xref="InterPro:IPR006225" /db_xref="InterPro:IPR020103" /db_xref="InterPro:IPR036986" /db_xref="SubtiList:BG11598" /db_xref="UniProtKB/Swiss-Prot:P54604" /translation="MNQKGRGLEILINEKQDGQWLFSVLKTALKASKPVIQDWMSHQQ IKVNHESVLNNMIVKKGDRVFIDLQESEASSVIPEYGELDILFEDNHMLIINKPAGIA THPNEDGQTGTLANLIAYHYQINGETCKVRHVHRLDQDTSGAIVFAKHRLAHAILDQQ LEKKTLKRTYTAIAEGKLRTKKGTINSPIGRDRSHPTRRRVSPGGQTAVTHFKVMASN AKERLSLVELELETGRTHQIRVHLASLGHPLTGDSLYGGGSKLLNRQALHANKVQAVH PITDELIVAEAPFPADMKNLCRTYFS*" gene complement(995624..996532) /gene="yhcT" /locus_tag="BSU_09210" /old_locus_tag="BSU09210" promotor_-35 996588..996596 /Source="Nicolas_upshift_promotors" /id="U721" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.57042957042957" /psig="0.999000999001" /xcortree=2026 /SigmaFactorBS="tttcgaagcggaaggctgctgtttctcataggaaacacttaC CTTAGCTTtcgcgtttttttcTGTGCTATTCTTGAGTAAGActtaggatattcgatgg c" /listShort="yhcU" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(996589..996600) /Source="Nicolas_upshift_promotors" /id="U720" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=803 /SigmaFactorBS="cctttcttgccatcgaatatcctaagtcttactcaAGAATAG cacagaaaaaaacGCGAAAGCTAAGgtaagtgtttcctatgagaaacagcagccttcc g" /listShort="yhcT" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(996595) /Source="Nicolas_upshifts" /id="U720" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=803 /SigmaFactorBS="cctttcttgccatcgaatatcctaagtcttactcaAGAATAG cacagaaaaaaacGCGAAAGCTAAGgtaagtgtttcctatgagaaacagcagccttcc g" /listShort="yhcT" /GFF_Attribute="listLong" S_feature complement(996597..997083) /Source="Nicolas_S_feature" /locus_tag="new_996597_997083_c" /HighExp="S8, dia15, Diami, H2O2, G180, G150, dia5, Paraq, Oxctl, S7" /AntisenseName="yhcU" /AntisenseCor="0.69394173601478304" /AntisenseRegPval="-39.200000000000003" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.958" /TUlongSig="NA" /TUlongPSig="NA" /label="S319" upshifts 996607 /Source="Nicolas_upshifts" /id="U721" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.57042957042957" /psig="0.999000999001" /xcortree=2026 /SigmaFactorBS="tttcgaagcggaaggctgctgtttctcataggaaacacttaC CTTAGCTTtcgcgtttttttcTGTGCTATTCTTGAGTAAGActtaggatattcgatgg c" /listShort="yhcU" /GFF_Attribute="listLong" promotor_-10 996610..996629 /Source="Nicolas_upshift_promotors" /id="U721" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.57042957042957" /psig="0.999000999001" /xcortree=2026 /SigmaFactorBS="tttcgaagcggaaggctgctgtttctcataggaaacacttaC CTTAGCTTtcgcgtttttttcTGTGCTATTCTTGAGTAAGActtaggatattcgatgg c" /listShort="yhcU" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 complement(996614..996620) /Source="Nicolas_upshift_promotors" /id="U720" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=803 /SigmaFactorBS="cctttcttgccatcgaatatcctaagtcttactcaAGAATAG cacagaaaaaaacGCGAAAGCTAAGgtaagtgtttcctatgagaaacagcagccttcc g" /listShort="yhcT" /GFF_Attribute="listLong" /label="promotor_-35" CDS 996643..997038 /gene="yhcU" /locus_tag="BSU_09220" /old_locus_tag="BSU09220" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_388803.2" /db_xref="EnsemblGenomes-Gn:BSU09220" /db_xref="EnsemblGenomes-Tr:CAB12750" /db_xref="InterPro:IPR020355" /db_xref="SubtiList:BG11599" /db_xref="UniProtKB/Swiss-Prot:P54605" /translation="MARKVIDVRIVNAATAEQESFIKELSMELIHDVFPLYFSELDIQ RFKKKGVLSLNNHYYQGTLKEAFQIMACLQMIHIILTKPSPHSDLSDQAIFEKNSKML NDFGIYFPFAFSDFQKKTNKAFFGQRRLI*" gene 996643..997038 /gene="yhcU" /locus_tag="BSU_09220" /old_locus_tag="BSU09220" misc_feature complement(997069..997088) /Source="Nicolas_upshift_promotors" /id="U722" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.709290709290709" /psig="0.958041958041958" /xcortree=1819 /SigmaFactorBS="cagacacgagccgtttaaaaagggagttagaggaaaggtttt atgatatgatttcTCTGATACAAAAAGAGCTTTtctaaaaatagaaaagcccttgccg c" /listShort="S319, yhcT" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(997083) /Source="Nicolas_upshifts" /id="U722" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.709290709290709" /psig="0.958041958041958" /xcortree=1819 /SigmaFactorBS="cagacacgagccgtttaaaaagggagttagaggaaaggtttt atgatatgatttcTCTGATACAAAAAGAGCTTTtctaaaaatagaaaagcccttgccg c" /listShort="S319, yhcT" /GFF_Attribute="listLong" promotor_-35 997123..997129 /Source="Nicolas_upshift_promotors" /id="U723" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp="0.99000999000999" /psig="0.99000999000999" /xcortree=842 /SigmaFactorBS="tttgtatcagagaaatcatatcataaaacctttcctctaact cccTTTTTAAacggctcgtgtctGAACATACTAATgattgaaaggggtgctgacaatg a" /listShort="yhcV" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 997138 /Source="Nicolas_upshifts" /id="U723" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp="0.99000999000999" /psig="0.99000999000999" /xcortree=842 /SigmaFactorBS="tttgtatcagagaaatcatatcataaaacctttcctctaact cccTTTTTAAacggctcgtgtctGAACATACTAATgattgaaaggggtgctgacaatg a" /listShort="yhcV" /GFF_Attribute="listLong" promotor_-10 997143..997154 /Source="Nicolas_upshift_promotors" /id="U723" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp="0.99000999000999" /psig="0.99000999000999" /xcortree=842 /SigmaFactorBS="tttgtatcagagaaatcatatcataaaacctttcctctaact cccTTTTTAAacggctcgtgtctGAACATACTAATgattgaaaggggtgctgacaatg a" /listShort="yhcV" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-10 complement(997153..997167) /Source="Nicolas_upshift_promotors" /id="U724" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.99000999000999" /psig="0.002997002997003" /xcortree=708 /SigmaFactorBS="ttcggagaaacggttgccacctgcgttgtcattgtatcttta actgaaCTCATtgtcagcACCCCTTTCAATCATtagtatgttcagacacgagccgttt a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(997167) /Source="Nicolas_upshifts" /id="U724" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.99000999000999" /psig="0.002997002997003" /xcortree=708 /SigmaFactorBS="ttcggagaaacggttgccacctgcgttgtcattgtatcttta actgaaCTCATtgtcagcACCCCTTTCAATCATtagtatgttcagacacgagccgttt a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(997175..997179) /Source="Nicolas_upshift_promotors" /id="U724" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.99000999000999" /psig="0.002997002997003" /xcortree=708 /SigmaFactorBS="ttcggagaaacggttgccacctgcgttgtcattgtatcttta actgaaCTCATtgtcagcACCCCTTTCAATCATtagtatgttcagacacgagccgttt a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" CDS 997175..997597 /gene="yhcV" /locus_tag="BSU_09230" /old_locus_tag="BSU09230" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 17322312; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative CBS containing enzyme (sporulation-/ germination-related)" /protein_id="NP_388804.1" /db_xref="EnsemblGenomes-Gn:BSU09230" /db_xref="EnsemblGenomes-Tr:CAB12751" /db_xref="InterPro:IPR000644" /db_xref="SubtiList:BG11600" /db_xref="UniProtKB/Swiss-Prot:P54606" /translation="MSSVKDTMTTQVATVSPNQTIQEAASLMKQHNVGAIPVVEQGVL KGMLTDRDIALRTTAQGRDGQTPVSEVMSTELVSGNPNMSLEDASQLMAQHQIRRLPI VDQNNLVGIVALGDLAVNQMSNESAGSALTNISHQNIH*" gene 997175..997597 /gene="yhcV" /locus_tag="BSU_09230" /old_locus_tag="BSU09230" promotor_no_box complement(997501..997601) /Source="Nicolas_upshift_promotors" /id="U725" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.3996003996004" /psig="0.014985014985015" /xcortree=1493 /SigmaFactorBS="cttattaatgaatgttttggtgagaaatgtttgtcagcgctg atcccgcagactcgttcgacatctgattgactgccaggtctccaagcgcaacgatccc g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_no_box" upshifts complement(997541) /Source="Nicolas_upshifts" /id="U725" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.3996003996004" /psig="0.014985014985015" /xcortree=1493 /SigmaFactorBS="cttattaatgaatgttttggtgagaaatgtttgtcagcgctg atcccgcagactcgttcgacatctgattgactgccaggtctccaagcgcaacgatccc g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" downshifts 997575 /Source="Nicolas_upshifts" /id="D476" /incds=0 /nref=50 /ntot=61 /MaxReadThrough="2.62549" /MaxDrop="7.03747" /score="-2.59023198" /energy="-12.1" /TU="NA" /idTUdmin="U723" /TUdmin=0 /isTUend="TRUE" downshifts complement(997607) /Source="Nicolas_upshifts" /id="D477" /incds=0 /nref=2 /ntot=10 /MaxReadThrough="0.0992700000000006" /MaxDrop="3.96142" /score="-9.32793172" /energy="-9.1" /TU="NA" /idTUdmin="U724" /TUdmin="-506" /isTUend="FALSE" promotor_-35 997647..997654 /Source="Nicolas_upshift_promotors" /id="U726" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.983016983016983" /psig=1 /xcortree=1997 /SigmaFactorBS="gtgcaggctctttcttcacataaaaccttacTTTTTGAAagc agacttgtttCGGGGTATAGTGAGTGTATAcatatgtctcaattcgtactaaaggagt t" /listShort="yhcW, yhcX, yhzG" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 997668..997687 /Source="Nicolas_upshift_promotors" /id="U726" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.983016983016983" /psig=1 /xcortree=1997 /SigmaFactorBS="gtgcaggctctttcttcacataaaaccttacTTTTTGAAagc agacttgtttCGGGGTATAGTGAGTGTATAcatatgtctcaattcgtactaaaggagt t" /listShort="yhcW, yhcX, yhzG" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 997676 /Source="Nicolas_upshifts" /id="U726" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.983016983016983" /psig=1 /xcortree=1997 /SigmaFactorBS="gtgcaggctctttcttcacataaaaccttacTTTTTGAAagc agacttgtttCGGGGTATAGTGAGTGTATAcatatgtctcaattcgtactaaaggagt t" /listShort="yhcW, yhcX, yhzG" /GFF_Attribute="listLong" CDS 997724..998386 /gene="glpW" /locus_tag="BSU_09240" /old_locus_tag="BSU09240" /EC_number="3.1.3.18" /EC_number="3.1.3.68" /EC_number="3.1.3.-" /function="16.3: Control" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 16990279, 22353596; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="promiscuous phosphoglycolate phosphatase / glycerol-3-phosphate phosphatase / 2-deoxyglucose-6-phosphatase" /protein_id="NP_388805.1" /db_xref="EnsemblGenomes-Gn:BSU09240" /db_xref="EnsemblGenomes-Tr:CAB12752" /db_xref="GOA:P54607" /db_xref="InterPro:IPR006439" /db_xref="InterPro:IPR023214" /db_xref="InterPro:IPR036412" /db_xref="SubtiList:BG11601" /db_xref="UniProtKB/Swiss-Prot:P54607" /translation="MIKALIFDFDGLILDTETHEYEVLQEIFEEHGSVLPLSVWGKVI GTAAGFRPFEYLEEQIGKKLNHEELTQLRRERFAKRMESEKARPGVEAYLNAAKDLGL KIGLASSSDYKWVSGHLKQIGLFDDFEVIQTADDVEEVKPNPELYLLAAKNLGVSPAE CLAFEDSVNGSIAAKRAGMKCVIVPNKVTGTLMFEDYDHRLESMAEMELALLLDHLNS QN*" gene 997724..998386 /gene="glpW" /locus_tag="BSU_09240" /old_locus_tag="BSU09240" CDS 998402..999943 /gene="yhcX" /locus_tag="BSU_09250" /old_locus_tag="BSU09250" /EC_number="3.5.-.-" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 26337367, 26808445, 17555270; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative amidohydrolase" /protein_id="NP_388806.2" /db_xref="EnsemblGenomes-Gn:BSU09250" /db_xref="EnsemblGenomes-Tr:CAB12753" /db_xref="GOA:P54608" /db_xref="InterPro:IPR000182" /db_xref="InterPro:IPR001110" /db_xref="InterPro:IPR003010" /db_xref="InterPro:IPR016181" /db_xref="InterPro:IPR036526" /db_xref="SubtiList:BG11602" /db_xref="UniProtKB/Swiss-Prot:P54608" /translation="MSEKLDLTRFEKKMVIRNIEEKDIDKIIDLQKDCFPGMEPWKRE HLISHLEHFPEGQFCAEFEGEIIGSCSSLLINFDEYDDRHTWQDITDDGYITNHNPDG LNMYGIEVMVHPKYRRMKIGHRLYEARKDLARRLNLKSIIIGGRIPNYHKYAEEMTAR EYVEQVTRHQIYDPVLSFQLMNGFTLMRINPNYLPDDTASIKYATLMEWNNVDYLPQQ TKRYYKSAFPVRICVIQYEMKKIYSFEEFANQVEYYVDVASDARSDFAVFPEIFTTQL MSFLEERSPSLAVQRITEYTEDYISLFTDLAVKYNVNIIGGSHFVEEEGKIYNIAYLF RRDGTIEKQYKLHITPNERKWWGISAGDQVRVFDTDCGKIAIQICYDIEFPELARIAA DKGAKIIFTPFCTEDRQGYLRVRYCSQARAVENQIYTVISGTVGNLPQTENMDIQYAQ SGIFAPSDFEFARDGIVGETNPNIEMVVIGDVDLEILRRQRQNGTVRQLKDRRRDIYH IQYKK*" gene 998402..999943 /gene="yhcX" /locus_tag="BSU_09250" /old_locus_tag="BSU09250" downshifts 999926 /Source="Nicolas_upshifts" /id="D478" /incds=0 /nref=57 /ntot=238 /MaxReadThrough="4.24486" /MaxDrop="5.06754" /score="24.7413026" /energy="-10.5" /TU="U726" /idTUdmin="U726" /TUdmin="-224" /isTUend="FALSE" CDS 1000027..1000218 /gene="yhzG" /locus_tag="BSU_09259" /old_locus_tag="BSU09259" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /pseudo /codon_start=1 /transl_table=11 /product="hypothetical protein" /db_xref="PSEUDO:CAX52585.1" /translation="MYSGCALWSFCIFAISYIIQKTARLHIAIAMAVQVVSSATFIST MLSIVTLPVLLWKLHPLSS*" gene 1000027..1000218 /gene="yhzG" /locus_tag="BSU_09259" /old_locus_tag="BSU09259" /pseudo promotor_-35 1000249..1000256 /Source="Nicolas_upshift_promotors" /id="U727" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.923076923076923" /psig=1 /xcortree=333 /SigmaFactorBS="aggggatgttttattatttacgcggttTATTGACTctgaccc ggtctggCTTTATATTGAAGGCAGGGAaatcatcaccaagacatcacataaagagaag g" /listShort="S320, yhxA, glpP, S321, glpF, glpK" /listLong="S322, glpD, S323, pgcA" /label="promotor_-35" promotor_-10 1000271..1000290 /Source="Nicolas_upshift_promotors" /id="U727" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.923076923076923" /psig=1 /xcortree=333 /SigmaFactorBS="aggggatgttttattatttacgcggttTATTGACTctgaccc ggtctggCTTTATATTGAAGGCAGGGAaatcatcaccaagacatcacataaagagaag g" /listShort="S320, yhxA, glpP, S321, glpF, glpK" /listLong="S322, glpD, S323, pgcA" /label="promotor_-10" S_feature 1000282..1000363 /Source="Nicolas_S_feature" /locus_tag="new_1000282_1000363" /HighExp="M40t90, M0t90, T0.30H, LBGstat, BC, Lbstat, M9-stat, Lbtran, T1.0H, T1.30H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S320" upshifts 1000282 /Source="Nicolas_upshifts" /id="U727" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.923076923076923" /psig=1 /xcortree=333 /SigmaFactorBS="aggggatgttttattatttacgcggttTATTGACTctgaccc ggtctggCTTTATATTGAAGGCAGGGAaatcatcaccaagacatcacataaagagaag g" /listShort="S320, yhxA, glpP, S321, glpF, glpK" /listLong="S322, glpD, S323, pgcA" CDS 1000364..1001716 /gene="yhxA" /locus_tag="BSU_09260" /old_locus_tag="BSU09260" /EC_number="2.6.-.-" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 11082195, 23610425; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative aminotransferase" /protein_id="NP_388807.2" /db_xref="EnsemblGenomes-Gn:BSU09260" /db_xref="EnsemblGenomes-Tr:CAB12754" /db_xref="GOA:P33189" /db_xref="InterPro:IPR005814" /db_xref="InterPro:IPR015421" /db_xref="InterPro:IPR015422" /db_xref="InterPro:IPR015424" /db_xref="SubtiList:BG10184" /db_xref="UniProtKB/Swiss-Prot:P33189" /translation="MEMMGMENIQQNQGLKQKDEQFVWHAMKGAHQADSLIAQKAEGA WVTDTDGRRYLDAMSGLWCVNIGYGRKELAEAAYEQLKELPYYPLTQSHAPAIQLAEK LNEWLGGDYVIFFSNSGSEANETAFKIARQYHLQNGDHSRYKFISRYRAYHGNTLGAL SATGQAQRKYKYEPLSQGFLHAAPPDIYRNPDDADTLESANEIDRIMTWELSETIAGV IMEPIITGGGILMPPDGYMKKVEDICRRHGALLICDEVICGFGRTGEPFGFMHYGVKP DIITMAKGITSAYLPLSATAVKRDIFEAYQGEAPYDRFRHVNTFGGSPAACALALKNL QIMEDEQLIQRSRDLGAKLLGELQALREHPAVGDVRGKGLLIGIELVKDKLTKEPADA AKVNQVVAACKEKGLIIGKNGDTVAGYNNVIQLAPPFCLTEEDLSFIVKTVKESFQTI *" gene 1000364..1001716 /gene="yhxA" /locus_tag="BSU_09260" /old_locus_tag="BSU09260" CDS 1001744..1002322 /gene="glpP" /locus_tag="BSU_09270" /old_locus_tag="BSU09270" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:11929549, 23610425, 22720735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11929549, 23610425, 22720735; Product type r: regulator" /codon_start=1 /transl_table=11 /product="sn-glycerol-3-phosphate responding transcriptionantiterminator" /protein_id="NP_388808.1" /db_xref="EnsemblGenomes-Gn:BSU09270" /db_xref="EnsemblGenomes-Tr:CAB12755" /db_xref="GOA:P30300" /db_xref="InterPro:IPR006699" /db_xref="InterPro:IPR035928" /db_xref="SubtiList:BG10185" /db_xref="UniProtKB/Swiss-Prot:P30300" /translation="MMSFHNQPILPAIRNMKQFDEFLNSSFSYGVILDIHLGQLKGVI KEAQKHGKNMMVHVDLIQGIKHDEYGAEFICQDIKPAGIISTRSNVIAKAKQKKIYAI QRLFLLDTSAMEKSMEFIGKHKPDFIEVLPGIVPSLIQEIKEKTGIPIFAGGFIRTEE DVEQALKAGAVAVTTSNTKLWKKYENFLTESD*" gene 1001744..1002322 /gene="glpP" /locus_tag="BSU_09270" /old_locus_tag="BSU09270" promotor_-35 1002317..1002324 /Source="Nicolas_upshift_promotors" /id="U728" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.605394605394605" /psig="0.998001998001998" /xcortree=276 /SigmaFactorBS="aaatatgaaaactttttgacggaaagtGATTGACAccgcttt catgcacTGATACAATTGCACTAGGTTaatacattgtgatggagaactcggagaccac a" /listShort="S321, glpF, glpK, S322, glpD, S323, pgcA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1002339..1002358 /Source="Nicolas_upshift_promotors" /id="U728" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.605394605394605" /psig="0.998001998001998" /xcortree=276 /SigmaFactorBS="aaatatgaaaactttttgacggaaagtGATTGACAccgcttt catgcacTGATACAATTGCACTAGGTTaatacattgtgatggagaactcggagaccac a" /listShort="S321, glpF, glpK, S322, glpD, S323, pgcA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1002350 /Source="Nicolas_upshifts" /id="U728" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.605394605394605" /psig="0.998001998001998" /xcortree=276 /SigmaFactorBS="aaatatgaaaactttttgacggaaagtGATTGACAccgcttt catgcacTGATACAATTGCACTAGGTTaatacattgtgatggagaactcggagaccac a" /listShort="S321, glpF, glpK, S322, glpD, S323, pgcA" /GFF_Attribute="listLong" downshifts 1002365 /Source="Nicolas_upshifts" /id="D479" /incds=0 /nref=3 /ntot=39 /MaxReadThrough="8.20986" /MaxDrop="2.99328" /score="6.07464219" /energy="-10" /TU="U727,U728" /idTUdmin="U726" /TUdmin=2215 /isTUend="FALSE" S_feature 1002410..1002500 /Source="Nicolas_S_feature" /locus_tag="new_1002410_1002500" /HighExp="Diami, T0.30H, G150, Oxctl, Gly, Paraq, dia5, BC, B60, H2O2" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="0.998, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S321" CDS 1002501..1003325 /gene="glpF" /locus_tag="BSU_09280" /old_locus_tag="BSU09280" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:11929549, 15849754, 16850406" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11929549, 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="glycerol permease" /protein_id="NP_388809.1" /db_xref="EnsemblGenomes-Gn:BSU09280" /db_xref="EnsemblGenomes-Tr:CAB12756" /db_xref="GOA:P18156" /db_xref="InterPro:IPR000425" /db_xref="InterPro:IPR022357" /db_xref="InterPro:IPR023271" /db_xref="SubtiList:BG10186" /db_xref="UniProtKB/Swiss-Prot:P18156" /translation="MTAFWGEVIGTMLLIIFGAGVCAGVNLKKSLSFQSGWIVVVFGW GLGVAMAAYAVGGISGAHLNPALTIALAFVGDFPWKEVPVYIAAQMIGAIIGAVIIYL HYLPHWKSTDDPAAKLGVFSTGPSIPHTFANVLSEVIGTFVLVLGILAIGANQFTEGL NPLIVGFLIVAIGISLGGTTGYAINPARDLGPRIAHAFLPIPGKGSSNWKYAWVPVVG PILGGSFGGVFYNAAFKGHITSSFWIVSVILVVVLLGLYVYTKSHSAKTLSNSKYI*" gene 1002501..1003325 /gene="glpF" /locus_tag="BSU_09280" /old_locus_tag="BSU09280" CDS 1003344..1004834 /gene="glpK" /locus_tag="BSU_09290" /old_locus_tag="BSU09290" /EC_number="2.7.1.30" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 9972264, 10920256, 11929549, 22720735; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="glycerol kinase (sn-glycerol-3-phosphate generating)" /protein_id="NP_388810.2" /db_xref="EnsemblGenomes-Gn:BSU09290" /db_xref="EnsemblGenomes-Tr:CAB12757" /db_xref="GOA:P18157" /db_xref="InterPro:IPR000577" /db_xref="InterPro:IPR005999" /db_xref="InterPro:IPR018483" /db_xref="InterPro:IPR018484" /db_xref="InterPro:IPR018485" /db_xref="SubtiList:BG10187" /db_xref="UniProtKB/Swiss-Prot:P18157" /translation="METYILSLDQGTTSSRAILFNKEGKIVHSAQKEFTQYFPHPGWV EHNANEIWGSVLAVIASVISESGISASQIAGIGITNQRETTVVWDKDTGSPVYNAIVW QSRQTSGICEELREKGYNDKFREKTGLLIDPYFSGTKVKWILDNVEGAREKAEKGELL FGTIDTWLIWKMSGGKAHVTDYSNASRTLMFNIYDLKWDDELLDILGVPKSMLPEVKP SSHVYAETVDYHFFGKNIPIAGAAGDQQSALFGQACFEEGMGKNTYGTGCFMLMNTGE KAIKSEHGLLTTIAWGIDGKVNYALEGSIFVAGSAIQWLRDGLRMFQDSSLSESYAEK VDSTDGVYVVPAFVGLGTPYWDSDVRGSVFGLTRGTTKEHFIRATLESLAYQTKDVLD AMEADSNISLKTLRVDGGAVKNNFLMQFQGDLLNVPVERPEINETTALGAAYLAGIAV GFWKDRSEIANQWNLDKRFEPELEEEKRNELYKGWQKAVKAAMAFK*" gene 1003344..1004834 /gene="glpK" /locus_tag="BSU_09290" /old_locus_tag="BSU09290" promotor_-35 1004145..1004151 /Source="Nicolas_upshift_promotors" /id="U729" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=149 /SigmaFactorBS="gcatggggaaaaacacttacggcacaggaTGTTTCAtgctga tgaataccGGGGAAAAAGCAATTAAGTCcgaacatgggcttttgacaacaatcgcttg g" /listShort="S322, glpD, S323" /listLong="pgcA" /label="promotor_-35" promotor_-10 1004166..1004185 /Source="Nicolas_upshift_promotors" /id="U729" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=149 /SigmaFactorBS="gcatggggaaaaacacttacggcacaggaTGTTTCAtgctga tgaataccGGGGAAAAAGCAATTAAGTCcgaacatgggcttttgacaacaatcgcttg g" /listShort="S322, glpD, S323" /listLong="pgcA" /label="promotor_-10" upshifts 1004176 /Source="Nicolas_upshifts" /id="U729" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=149 /SigmaFactorBS="gcatggggaaaaacacttacggcacaggaTGTTTCAtgctga tgaataccGGGGAAAAAGCAATTAAGTCcgaacatgggcttttgacaacaatcgcttg g" /listShort="S322, glpD, S323" /listLong="pgcA" S_feature 1004835..1004923 /Source="Nicolas_S_feature" /locus_tag="new_1004835_1004923" /HighExp="Sw, Etha, Salt, G150, Gly, Diami, T0.30H, B60, BC, Oxctl" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigB, SigA" /TUshortPSig="1, 0.998" /TUlongSig="SigA" /TUlongPSig=1 /label="S322" downshifts 1004880 /Source="Nicolas_upshifts" /id="D480" /incds=0 /nref=34 /ntot=91 /MaxReadThrough="7.63856" /MaxDrop="5.2045" /score="21.1943866" /energy="-28.7" /TU="U728,U729" /idTUdmin="U727" /TUdmin=0 /isTUend="TRUE" promotor_no_box 1004886..1004986 /Source="Nicolas_upshift_promotors" /id="U730" /multdbtbs="-" /comp="M21" /sig="Sig-" /pcomp="0.566433566433566" /psig="0.154845154845155" /xcortree=277 /SigmaFactorBS="aggagagaccacagcaccaaagtgtaagcatgcactttggct gttgtggtctctttttctatttaccgtgacaacaaggaggaaacgtaatgatgaatca t" /listShort="glpD, S323, pgcA" /GFF_Attribute="listLong" /label="promotor_no_box" upshifts 1004946 /Source="Nicolas_upshifts" /id="U730" /multdbtbs="-" /comp="M21" /sig="Sig-" /pcomp="0.566433566433566" /psig="0.154845154845155" /xcortree=277 /SigmaFactorBS="aggagagaccacagcaccaaagtgtaagcatgcactttggct gttgtggtctctttttctatttaccgtgacaacaaggaggaaacgtaatgatgaatca t" /listShort="glpD, S323, pgcA" /GFF_Attribute="listLong" CDS 1004975..1006642 /gene="glpD" /locus_tag="BSU_09300" /old_locus_tag="BSU09300" /EC_number="1.1.3.21" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:2127799, 8825777, 9595668, 10633102, 18946204" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 2127799, 8825777, 9595668, 10633102, 18946204; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="sn-glycerol-3-phosphate oxidase (FAD-dependent)" /protein_id="NP_388811.2" /db_xref="EnsemblGenomes-Gn:BSU09300" /db_xref="EnsemblGenomes-Tr:CAB12758" /db_xref="GOA:P18158" /db_xref="InterPro:IPR000447" /db_xref="InterPro:IPR006076" /db_xref="InterPro:IPR031656" /db_xref="InterPro:IPR036188" /db_xref="SubtiList:BG10188" /db_xref="UniProtKB/Swiss-Prot:P18158" /translation="MMNHQFSSLERDRMLTDMTKKTYDLFIIGGGITGAGTALDAASR GMKVALSEMQDFAAGTSSRSTKLVHGGLRYLKQFEVKMVAEVGKERAIVYENGPHVTT PEWMLLPFHKGGTFGSFTTSIGLRVYDFLAGVKKSERRSMLSAKETLQKEPLVKKDGL KGGGYYVEYRTDDARLTIEVMKEAVKFGAEPVNYSKVKELLYEKGKAVGVLIEDVLTK KEYKVYAKKIVNATGPWVDQLREKDHSKNGKHLQHTKGIHLVFDQSVFPLKQAVYFDT PDGRMVFAIPREGKTYVGTTDTVYKEALEHPRMTTEDRDYVIKSINYMFPELNITAND IESSWAGLRPLIHEEGKDPSEISRKDEIWTSDSGLITIAGGKLTGYRKMAEHIVDLVR DRLKEEGEKDFGPCKTKNMPISGGHVGGSKNLMSFVTAKTKEGIAAGLSEKDAKQLAI RYGSNVDRVFDRVEALKDEAAKRNIPVHILAEAEYSIEEEMTATPADFFVRRTGRLFF DINWVRTYKDAVIDFMSERFQWDEQAKNKHTENLNKLLHDAVVPLEQ*" gene 1004975..1006642 /gene="glpD" /locus_tag="BSU_09300" /old_locus_tag="BSU09300" promotor_-35 1006404..1006409 /Source="Nicolas_upshift_promotors" /id="U731" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.995004995004995" /psig="0.995004995004995" /xcortree=1176 /SigmaFactorBS="aaagatgaggccgcgaaacgcaacattccggTTCATAttctt gctgaggcaGAATACAGTATAGAAGAAGagatgactgcaacccctgctgacttctttg t" /listShort="S323" /listLong="pgcA" /label="promotor_-35" promotor_-10 1006424..1006442 /Source="Nicolas_upshift_promotors" /id="U731" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.995004995004995" /psig="0.995004995004995" /xcortree=1176 /SigmaFactorBS="aaagatgaggccgcgaaacgcaacattccggTTCATAttctt gctgaggcaGAATACAGTATAGAAGAAGagatgactgcaacccctgctgacttctttg t" /listShort="S323" /listLong="pgcA" /label="promotor_-10" upshifts 1006433 /Source="Nicolas_upshifts" /id="U731" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.995004995004995" /psig="0.995004995004995" /xcortree=1176 /SigmaFactorBS="aaagatgaggccgcgaaacgcaacattccggTTCATAttctt gctgaggcaGAATACAGTATAGAAGAAGagatgactgcaacccctgctgacttctttg t" /listShort="S323" /listLong="pgcA" promotor_-35 1006487..1006493 /Source="Nicolas_upshift_promotors" /id="U732" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=255 /SigmaFactorBS="actgcaacccctgctgacttctttgtccgcagaacgggaCGT TTATtttttgatatcaattGGGTAAGAACATATAAAGAtgccgttattgattttatga g" /listShort="S323, pgcA, S324, yhcY, yhcZ, yhdA" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 1006508 /Source="Nicolas_upshifts" /id="U732" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=255 /SigmaFactorBS="actgcaacccctgctgacttctttgtccgcagaacgggaCGT TTATtttttgatatcaattGGGTAAGAACATATAAAGAtgccgttattgattttatga g" /listShort="S323, pgcA, S324, yhcY, yhcZ, yhdA" /GFF_Attribute="listLong" promotor_-10 1006509..1006527 /Source="Nicolas_upshift_promotors" /id="U732" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=255 /SigmaFactorBS="actgcaacccctgctgacttctttgtccgcagaacgggaCGT TTATtttttgatatcaattGGGTAAGAACATATAAAGAtgccgttattgattttatga g" /listShort="S323, pgcA, S324, yhcY, yhcZ, yhdA" /GFF_Attribute="listLong" /label="promotor_-10" downshifts 1006610 /Source="Nicolas_upshifts" /id="D481" /incds=0 /nref=13 /ntot=60 /MaxReadThrough="6.57605" /MaxDrop="4.31183" /score="11.5542287" /energy="-11.4" /TU="U728,U729,U730,U731,U732" /idTUdmin="U729" /TUdmin="-118" /isTUend="FALSE" S_feature 1006655..1006728 /Source="Nicolas_S_feature" /locus_tag="new_1006655_1006728" /HighExp="G150, Etha, Oxctl, H2O2, Gly, Diami, Paraq, Salt, B36, BT" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigB, SigEF, Sig-, SigB, SigA" /TUshortPSig="1, 0.995, 0.155, 1, 0.998" /TUlongSig="SigA" /TUlongPSig=1 /label="S323" promotor_-35 1006710..1006717 /Source="Nicolas_upshift_promotors" /id="U733" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.915084915084915" /psig="0.998001998001998" /xcortree=1942 /SigmaFactorBS="atttctttttacgtgccgaaagggggagatctcaggttatCA AGTGACagaggcacccgctTCATATAAAATAATGGCATAagctgatacataggaggac g" /listShort="pgcA, S324, yhcY, yhcZ, yhdA" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 1006730 /Source="Nicolas_upshifts" /id="U733" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.915084915084915" /psig="0.998001998001998" /xcortree=1942 /SigmaFactorBS="atttctttttacgtgccgaaagggggagatctcaggttatCA AGTGACagaggcacccgctTCATATAAAATAATGGCATAagctgatacataggaggac g" /listShort="pgcA, S324, yhcY, yhcZ, yhdA" /GFF_Attribute="listLong" promotor_-10 1006731..1006750 /Source="Nicolas_upshift_promotors" /id="U733" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.915084915084915" /psig="0.998001998001998" /xcortree=1942 /SigmaFactorBS="atttctttttacgtgccgaaagggggagatctcaggttatCA AGTGACagaggcacccgctTCATATAAAATAATGGCATAagctgatacataggaggac g" /listShort="pgcA, S324, yhcY, yhcZ, yhdA" /GFF_Attribute="listLong" /label="promotor_-10" CDS 1006774..1008519 /gene="pgcA" /locus_tag="BSU_09310" /old_locus_tag="BSU09310" /EC_number="5.4.2.2" /function="16.13: Shape" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:15640167, 17662947, 24097947, 26735940, 27684739" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15640167, 17662947, 24097947, 26735940, 27684739; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="alpha-phosphoglucomutase" /protein_id="NP_388812.2" /db_xref="EnsemblGenomes-Gn:BSU09310" /db_xref="EnsemblGenomes-Tr:CAB12759" /db_xref="GOA:P18159" /db_xref="InterPro:IPR005841" /db_xref="InterPro:IPR005843" /db_xref="InterPro:IPR005844" /db_xref="InterPro:IPR005845" /db_xref="InterPro:IPR005846" /db_xref="InterPro:IPR016055" /db_xref="InterPro:IPR016066" /db_xref="InterPro:IPR036900" /db_xref="SubtiList:BG10189" /db_xref="UniProtKB/Swiss-Prot:P18159" /translation="MTWRKSYERWKQTEHLDLELKERLIELEGDEQALEDCFYKDLEF GTGGMRGEIGAGTNRMNIYTVRKASAGFAAYISKQGEEAKKRGVVIAYDSRHKSPEFA MEAAKTLATQGIQTYVFDELRPTPELSFAVRQLNAYGGIVVTASHNPPEYNGYKVYGD DGGQLPPKEADIVIEQVNAIENELTITVDEENKLKEKGLIKIIGEDIDKVYTEKLTSI SVHPELSEEVDVKVVFTPLHGTANKPVRRGLEALGYKNVTVVKEQELPDSNFSTVTSP NPEEHAAFEYAIKLGEEQNADILIATDPDADRLGIAVKNDQGKYTVLTGNQTGALLLH YLLSEKKKQGILPDNGVVLKTIVTSEIGRAVASSFGLDTIDTLTGFKFIGEKIKEYEA SGQYTFQFGYEESYGYLIGDFARDKDAIQAALLAVEVCAFYKKQGMSLYEALINLFNE YGFYREGLKSLTLKGKQGAEQIEAILASFRQNPPQKMAGKQVVTAEDYAVSKRTLLTE SKEEAIDLPKSNVLKYFLEDGSWFCLRPSGTEPKVKFYFAVKGSSLEDSEKRLAVLSE DVMKTVDEIVESTAK*" gene 1006774..1008519 /gene="pgcA" /locus_tag="BSU_09310" /old_locus_tag="BSU09310" downshifts 1008508 /Source="Nicolas_upshifts" /id="D482" /incds=0 /nref=227 /ntot=264 /MaxReadThrough="4.80136" /MaxDrop="5.89896" /score="26.7163878" /energy="-13" /TU="U732,U733" /idTUdmin="U728" /TUdmin="-6" /isTUend="TRUE" S_feature 1008553..1008622 /Source="Nicolas_S_feature" /locus_tag="new_1008553_1008622" /HighExp="Etha, H2O2, B36, dia15, Paraq, G150, LoTm, S8, Oxctl, Heat" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigB" /TUshortPSig="0.998, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S324" misc_feature 1008624..1008643 /Source="Nicolas_upshift_promotors" /id="U734" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.62037962037962" /psig="0.998001998001998" /xcortree=3137 /SigmaFactorBS="tttctcatccaaaagtctgaaagaaaatcatcctacaagtga agcaatgaaatacaaaaaACTGGTATAATCTTAAATACaagatcaatgccggagtgag a" /listShort="yhcY, yhcZ, yhdA" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 1008624 /Source="Nicolas_upshifts" /id="U734" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.62037962037962" /psig="0.998001998001998" /xcortree=3137 /SigmaFactorBS="tttctcatccaaaagtctgaaagaaaatcatcctacaagtga agcaatgaaatacaaaaaACTGGTATAATCTTAAATACaagatcaatgccggagtgag a" /listShort="yhcY, yhcZ, yhdA" /GFF_Attribute="listLong" CDS 1008668..1009807 /gene="yhcY" /locus_tag="BSU_09320" /old_locus_tag="BSU09320" /function="16.3: Control" /function="16.12: Sense" /experiment="publication(s) with functional evidences, PMID:11717295, 16816187, 16267314, 20639339, 21335452" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11717295, 16816187, 16267314, 20639339, 21335452; Product type rc: receptor" /codon_start=1 /transl_table=11 /product="two-component sensor histidine kinase [YhcZ]" /protein_id="NP_388813.1" /db_xref="EnsemblGenomes-Gn:BSU09320" /db_xref="EnsemblGenomes-Tr:CAB12760" /db_xref="GOA:O07527" /db_xref="InterPro:IPR003018" /db_xref="InterPro:IPR003594" /db_xref="InterPro:IPR011712" /db_xref="InterPro:IPR029016" /db_xref="InterPro:IPR036890" /db_xref="SubtiList:BG13005" /db_xref="UniProtKB/Swiss-Prot:O07527" /translation="MSKTRMEKLKTLKTIAETLNQGHDIKATLDEVLKELLSLTNLQS GWIFLIEEDGSYTLAADAYLPPALSRKEKVLMCEGECYCLTKFNNGGLRKAANIMNCK RIESAENLHCFDTEGITHHATVPLEDGDRRFGLLNVAAAGKTMFDEEELHLLESVAFQ IGTAIQRMRLSEYQQKNALLMERNRLAQELHDSVNQMLFSVSLTAKAAKTLTKDENLQ QMIDFIQNLSQDALAEMKALIWQLRPGGLEKGLAEAIKSYGALIGLKIIFTQKGCPVL TDEQEHMLWRVVQEALNNCKKHAGTDTAYVSLTASLCHAELDIIDHGAGFRYEAHAGL PSLGIKGMKERAEKAGAKFWIESALGTGTKLSIRLPLKSRKGGAV*" gene 1008668..1009807 /gene="yhcY" /locus_tag="BSU_09320" /old_locus_tag="BSU09320" CDS 1009804..1010448 /gene="yhcZ" /locus_tag="BSU_09330" /old_locus_tag="BSU09330" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:11717295, 16816187, 16267314, 20639339, 21335452" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11717295, 16816187, 16267314, 20639339, 21335452; Product type r: regulator" /codon_start=1 /transl_table=11 /product="two-component response regulator [YhcY]" /protein_id="NP_388814.1" /db_xref="EnsemblGenomes-Gn:BSU09330" /db_xref="EnsemblGenomes-Tr:CAB12761" /db_xref="GOA:O07528" /db_xref="InterPro:IPR000792" /db_xref="InterPro:IPR001789" /db_xref="InterPro:IPR011006" /db_xref="InterPro:IPR016032" /db_xref="InterPro:IPR036388" /db_xref="SubtiList:BG13006" /db_xref="UniProtKB/Swiss-Prot:O07528" /translation="MKIVIADDHHVVRKGLRFFFATQDDIEVVGEAATGLEALRVIEE TKPDLVLMDLSMPEMDGIQAIKKAIQQFPDTNIIVLTSYSDQEHVIPALQAGAKAYQL KDTEPEELVKTRQVHGGEYKLSTAIMPHVLTHMKNQHDPEKEKYYQLTRREKDVLTEI ANGKSNKEIAAALFISEKTVKTHVSNLLAKLEVADRTQAALFAVKYNLNGEISK*" gene 1009804..1010448 /gene="yhcZ" /locus_tag="BSU_09330" /old_locus_tag="BSU09330" CDS 1010445..1010969 /gene="azr" /locus_tag="BSU_09340" /old_locus_tag="BSU09340" /EC_number="1.7.1.-" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 15184374, 16816187, 20639339; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="oxidoreductase, NAD(P)H-FMN and ferric iron reductase (azoreductase)" /protein_id="NP_388815.1" /db_xref="EnsemblGenomes-Gn:BSU09340" /db_xref="EnsemblGenomes-Tr:CAB12762" /db_xref="GOA:O07529" /db_xref="InterPro:IPR005025" /db_xref="InterPro:IPR029039" /db_xref="PDB:1NNI" /db_xref="PDB:2GSW" /db_xref="PDB:3GFQ" /db_xref="PDB:3GFR" /db_xref="PDB:3GFS" /db_xref="SubtiList:BG13007" /db_xref="UniProtKB/Swiss-Prot:O07529" /translation="MNMLVINGTPRKHGRTRIAASYIAALYHTDLIDLSEFVLPVFNG EAEQSELLKVQELKQRVTKADAIVLLSPEYHSGMSGALKNALDFLSSEQFKYKPVALL AVAGGGKGGINALNNMRTVMRGVYANVIPKQLVLDPVHIDVENATVAENIKESIKELV EELSMFAKAGNPGV*" gene 1010445..1010969 /gene="azr" /locus_tag="BSU_09340" /old_locus_tag="BSU09340" downshifts 1010934 /Source="Nicolas_upshifts" /id="D483" /incds=0 /nref=72 /ntot=215 /MaxReadThrough="2.90096" /MaxDrop="4.78561" /score="27.1269177" /energy="-17.2" /TU="NA" /idTUdmin="U734" /TUdmin=0 /isTUend="TRUE" CDS complement(1010984..1011226) /gene="yhdB" /locus_tag="BSU_09350" /old_locus_tag="BSU09350" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_388816.1" /db_xref="EnsemblGenomes-Gn:BSU09350" /db_xref="EnsemblGenomes-Tr:CAB12763" /db_xref="InterPro:IPR025431" /db_xref="SubtiList:BG13008" /db_xref="UniProtKB/Swiss-Prot:O07530" /translation="MDYADYDKALYYTHRSQWDNLLILMVRTEDDLLSKRIEHFLHAY HFEQDYAVLEKMLYSLLRYIDHATELTYEDQIALLT*" gene complement(1010984..1011226) /gene="yhdB" /locus_tag="BSU_09350" /old_locus_tag="BSU09350" downshifts complement(1011005) /Source="Nicolas_upshifts" /id="D484" /incds=0 /nref=39 /ntot=84 /MaxReadThrough="-0.0235599999999998" /MaxDrop="7.78706" /score="12.0066876" /energy="-17.2" /TU="NA" /idTUdmin="U735" /TUdmin="-17" /isTUend="TRUE" promotor_-10 complement(1011262..1011273) /Source="Nicolas_upshift_promotors" /id="U735" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.556443556443556" /psig="0.556443556443556" /xcortree=833 /SigmaFactorBS="attgctacccctttactgacgcagacggcaagttttgccCCG TCAATaacagaggatgcgGCATAAACTAATcatgaacttctcacccaagaaaggagaa g" /listShort="yhdB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1011273) /Source="Nicolas_upshifts" /id="U735" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.556443556443556" /psig="0.556443556443556" /xcortree=833 /SigmaFactorBS="attgctacccctttactgacgcagacggcaagttttgccCCG TCAATaacagaggatgcgGCATAAACTAATcatgaacttctcacccaagaaaggagaa g" /listShort="yhdB" /GFF_Attribute="listLong" promotor_-35 complement(1011287..1011294) /Source="Nicolas_upshift_promotors" /id="U735" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.556443556443556" /psig="0.556443556443556" /xcortree=833 /SigmaFactorBS="attgctacccctttactgacgcagacggcaagttttgccCCG TCAATaacagaggatgcgGCATAAACTAATcatgaacttctcacccaagaaaggagaa g" /listShort="yhdB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1011361..1011367 /Source="Nicolas_upshift_promotors" /id="U736" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=929 /SigmaFactorBS="aatatgagggagacataaaatcaaaatgccTGAATGAagata tcgcttttGGTAAACCTATGagggaatatattctgggtacaggagactgaaaaaatga a" /listShort="yhdC, S325" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1011381..1011392 /Source="Nicolas_upshift_promotors" /id="U736" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=929 /SigmaFactorBS="aatatgagggagacataaaatcaaaatgccTGAATGAagata tcgcttttGGTAAACCTATGagggaatatattctgggtacaggagactgaaaaaatga a" /listShort="yhdC, S325" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1011391 /Source="Nicolas_upshifts" /id="U736" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=929 /SigmaFactorBS="aatatgagggagacataaaatcaaaatgccTGAATGAagata tcgcttttGGTAAACCTATGagggaatatattctgggtacaggagactgaaaaaatga a" /listShort="yhdC, S325" /GFF_Attribute="listLong" CDS 1011427..1011750 /gene="yhdC" /locus_tag="BSU_09360" /old_locus_tag="BSU09360" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type f: factor" /codon_start=1 /transl_table=11 /product="putative exported protein" /protein_id="NP_388817.1" /db_xref="EnsemblGenomes-Gn:BSU09360" /db_xref="EnsemblGenomes-Tr:CAB12764" /db_xref="InterPro:IPR024987" /db_xref="SubtiList:BG13009" /db_xref="UniProtKB/Swiss-Prot:O07531" /translation="MKSLPYTIALLFCGLIIVSMAAKGHSTDTDESVQKWEQLAWSKI QDEYKGASFSDYAYMGRTEVNDQQTKDVFRVTVRQKDDTFSVRAEVYFHPVTNHMISI NVFRL*" gene 1011427..1011750 /gene="yhdC" /locus_tag="BSU_09360" /old_locus_tag="BSU09360" S_feature 1011751..1013617 /Source="Nicolas_S_feature" /locus_tag="new_1011751_1013617" /HighExp="S8, S5, S7, S6, S4, C30, Sw, ferm, S3, BC" /AntisenseName="lytF" /AntisenseCor="-0.65564579825076796" /AntisenseRegPval="-33.700000000000003" /CDS_PredictionProba="NA" /TUshortSig="SigGF" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S325" CDS complement(1011792..1013258) /gene="lytF" /locus_tag="BSU_09370" /old_locus_tag="BSU09370" /EC_number="3.4.-.-" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:10206711, 14594841, 18761694, 18761696, 23091053, 25288647" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10206711, 14594841, 18761694, 18761696, 23091053, 25288647; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="gamma-D-glutamate-meso-diaminopimelate muropeptidase (major autolysin, vegetative)" /protein_id="NP_388818.2" /db_xref="EnsemblGenomes-Gn:BSU09370" /db_xref="EnsemblGenomes-Tr:CAB12776" /db_xref="GOA:O07532" /db_xref="InterPro:IPR000064" /db_xref="InterPro:IPR018392" /db_xref="InterPro:IPR036779" /db_xref="SubtiList:BG13010" /db_xref="UniProtKB/Swiss-Prot:O07532" /translation="MKKKLAAGLTASAIVGTTLVVTPAEAATIKVKSGDSLWKLAQTY NTSVAALTSANHLSTTVLSIGQTLTIPGSKSSTSSSTSSSTTKKSGSSVYTVKSGDSL WLIANEFKMTVQELKKLNGLSSDLIRAGQKLKVSGTVSSSSSSSKKSNSNKSSSSSSK SSSNKSSSSSSSTGTYKVQLGDSLWKIANKVNMSIAELKVLNNLKSDTIYVNQVLKTK SSGSDTSSKDNSSKSNQTSATTKYTVKSGDSLWKIANNYNLTVQQIRNINNLKSDVLY VGQVLKLTGKASSGSSSSSSSSSNASSGTTTTYTVKSGDSLWVIAQKFNVTAQQIREK NNLKTDVLQVGQKLVISGKASSSSSSGSSNTTSSTSAKINTMISAAKAQLGVPYRWGG TTPSGFDCSGFIYYVLNKVTSVSRLTAAGYWNTMKSVSQPAVGDFVFFSTYKAGPSHV GIYLGNGEFINANDSGVVISNMNNSYWKQRYLGAKRYF*" gene complement(1011792..1013258) /gene="lytF" /locus_tag="BSU_09370" /old_locus_tag="BSU09370" downshifts complement(1011804) /Source="Nicolas_upshifts" /id="D485" /incds=0 /nref=121 /ntot=216 /MaxReadThrough="2.34529" /MaxDrop="4.33563" /score="24.6732339" /energy="-14.2" /TU="NA" /idTUdmin="U737" /TUdmin="-1" /isTUend="TRUE" downshifts complement(1011891) /Source="Nicolas_upshifts" /id="D486" /incds=1 /nref=1 /ntot=87 /MaxReadThrough="5.73069" /MaxDrop="2.6306" /score="24.6732339" /energy="-14.2" /TU="U737" /idTUdmin="U737" /TUdmin="-88" /isTUend="FALSE" promotor_-10 complement(1013298..1013316) /Source="Nicolas_upshift_promotors" /id="U737" /multdbtbs="SigD" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2806 /SigmaFactorBS="ttgttaagataatttggctatttttataaaaagGCAAAACGa tgagacaaatgtGCCGATATAAAAAAGAAACagcaaatgcaaaatcattgggggaaaa a" /listShort="lytF" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1013310) /Source="Nicolas_upshifts" /id="U737" /multdbtbs="SigD" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2806 /SigmaFactorBS="ttgttaagataatttggctatttttataaaaagGCAAAACGa tgagacaaatgtGCCGATATAAAAAAGAAACagcaaatgcaaaatcattgggggaaaa a" /listShort="lytF" /GFF_Attribute="listLong" promotor_-35 complement(1013330..1013337) /Source="Nicolas_upshift_promotors" /id="U737" /multdbtbs="SigD" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2806 /SigmaFactorBS="ttgttaagataatttggctatttttataaaaagGCAAAACGa tgagacaaatgtGCCGATATAAAAAAGAAACagcaaatgcaaaatcattgggggaaaa a" /listShort="lytF" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(1013411..1013851) /gene="nsrR" /locus_tag="BSU_09380" /old_locus_tag="BSU09380" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:16885456, 19006327, 21091510, 26887943, 27778474, 28425466, 28439033" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16885456, 19006327, 21091510, 26887943, 27778474, 28425466, 28439033; Product type r: regulator" /codon_start=1 /transl_table=11 /product="NO-dependent activator of the ResDE regulon (Fe-S NO binding site)" /protein_id="NP_388819.1" /db_xref="EnsemblGenomes-Gn:BSU09380" /db_xref="EnsemblGenomes-Tr:CAB12777" /db_xref="GOA:O07573" /db_xref="InterPro:IPR000944" /db_xref="InterPro:IPR030489" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG13011" /db_xref="UniProtKB/Swiss-Prot:O07573" /translation="MKLTNYTDYSLRVLIFLAAERPGELSNIKQIAETYSISKNHLMK VIYRLGQLGYVETIRGRGGGIRLGMDPEDINIGEVVRKTEDDFNIVECFDANKNLCVI SPVCGLKHVLNEALLAYLAVLDKYTLRDLVKNKEDIMKLLKMKE*" gene complement(1013411..1013851) /gene="nsrR" /locus_tag="BSU_09380" /old_locus_tag="BSU09380" downshifts complement(1013441) /Source="Nicolas_upshifts" /id="D487" /incds=0 /nref=205 /ntot=265 /MaxReadThrough="3.11158" /MaxDrop="6.87147" /score="5.96186156" /energy="-7.8" /TU="U739" /idTUdmin="U740" /TUdmin="-10" /isTUend="TRUE" promotor_-35 1013839..1013845 /Source="Nicolas_upshift_promotors" /id="U738" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.904095904095904" /psig="0.904095904095904" /xcortree=408 /SigmaFactorBS="cagaaaaatcaacactcttaatgaataatctgtataatTGGT TAActtcataataagaCCTCAGAATAAGacattttctatatcttatcataatcgattg a" /listShort="S326" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1013859..1013870 /Source="Nicolas_upshift_promotors" /id="U738" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.904095904095904" /psig="0.904095904095904" /xcortree=408 /SigmaFactorBS="cagaaaaatcaacactcttaatgaataatctgtataatTGGT TAActtcataataagaCCTCAGAATAAGacattttctatatcttatcataatcgattg a" /listShort="S326" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 1013861..1013971 /Source="Nicolas_S_feature" /locus_tag="new_1013861_1013971" /HighExp="S8, S7, S4, Sw, S5, S6, BC, B60, nit, Pyr" /AntisenseName="ygxB" /AntisenseCor="-0.211236686077168" /AntisenseRegPval="-3.3" /CDS_PredictionProba="NA" /TUshortSig="SigGF" /TUshortPSig="0.904" /TUlongSig="NA" /TUlongPSig="NA" /label="S326" upshifts 1013861 /Source="Nicolas_upshifts" /id="U738" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.904095904095904" /psig="0.904095904095904" /xcortree=408 /SigmaFactorBS="cagaaaaatcaacactcttaatgaataatctgtataatTGGT TAActtcataataagaCCTCAGAATAAGacattttctatatcttatcataatcgattg a" /listShort="S326" /GFF_Attribute="listLong" promotor_-10 complement(1013873..1013892) /Source="Nicolas_upshift_promotors" /id="U739" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.93906093906094" /psig=1 /xcortree=3120 /SigmaFactorBS="catgcacccagctgggtgcatgttttttaattcctttttTTT CATTtttcaatcgatTATGATAAGATATAGAAAATgtcttattctgaggtcttattat g" /listShort="nsrR, lytF" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1013889) /Source="Nicolas_upshifts" /id="U739" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.93906093906094" /psig=1 /xcortree=3120 /SigmaFactorBS="catgcacccagctgggtgcatgttttttaattcctttttTTT CATTtttcaatcgatTATGATAAGATATAGAAAATgtcttattctgaggtcttattat g" /listShort="nsrR, lytF" /GFF_Attribute="listLong" promotor_-35 complement(1013904..1013910) /Source="Nicolas_upshift_promotors" /id="U739" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.93906093906094" /psig=1 /xcortree=3120 /SigmaFactorBS="catgcacccagctgggtgcatgttttttaattcctttttTTT CATTtttcaatcgatTATGATAAGATATAGAAAATgtcttattctgaggtcttattat g" /listShort="nsrR, lytF" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 1013930 /Source="Nicolas_upshifts" /id="D488" /incds=0 /nref=10 /ntot=68 /MaxReadThrough="1.05981" /MaxDrop="6.25571" /score="22.5171081" /energy="-11.6" /TU="NA" /idTUdmin="U738" /TUdmin=3 /isTUend="TRUE" CDS complement(1013958..1015616) /gene="ygxB" /locus_tag="BSU_09390" /old_locus_tag="BSU09390" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative integral membrane protein" /protein_id="NP_388820.1" /db_xref="EnsemblGenomes-Gn:BSU09390" /db_xref="EnsemblGenomes-Tr:CAB12778" /db_xref="GOA:P37874" /db_xref="InterPro:IPR008910" /db_xref="SubtiList:BG10181" /db_xref="UniProtKB/Swiss-Prot:P37874" /translation="MYEPARQKMIVSLGQEKIPPAHSSVCLLDKWVNTHHTTKKERYQ LNVADVFSSYLSKLPNVIIALLVLLIGWAIAKIIEKAVYKGLSKTKIDDKLFAGKKPS RYSSEKVISKVVYFIALIIVFILFFNILHLTTVASPFVSMLSAIAAAIPSVLKAGLIL LLGWAAASVLSFLVKKIGMKLNTSDKLRKWNLVSEGKDIHQAVNTASQIVFYLVLLVF LPGVLSSLKISGISGPFTNMMESVLAFLPKLFAAALIVLIGWLVARLVRDIITNFLAS IGTERFAARMGLSIYLKDTSLSAVIGTIAYVLIMIPVVISALDQLDVAGISKPAVSML NTILNMLPNIMIAIVLVLAGIWAGKWVKSMVSGLLHRAGFDSVLGKMGMEAGTPAKLS LSQVVGMIAQIIVILLFTAEALQIVRLHFLVEIATGIIAYLPNVLVAVFILGLGLYAG ELVRKVLASMIKGQEFKSLAPIAKYTIIALAFFMALDQLGVAATIVNSAFIIVLSGFA LAFGLSFGLGGKDFASRYLSTFERKMQNTEIEKNRKNQNPPNDM*" gene complement(1013958..1015616) /gene="ygxB" /locus_tag="BSU_09390" /old_locus_tag="BSU09390" downshifts complement(1013963) /Source="Nicolas_upshifts" /id="D489" /incds=0 /nref=6 /ntot=40 /MaxReadThrough="8.34865" /MaxDrop="5.55332" /score="-5.46969987" /energy="-14.5" /TU="U740" /idTUdmin="U740" /TUdmin="-532" /isTUend="FALSE" promotor_-10 complement(1015507..1015525) /Source="Nicolas_upshift_promotors" /id="U740" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=189 /SigmaFactorBS="agtctcactcgggcaagaaaaaattcccccggcacattcatc TGTTTGCttattggataagtGGGTAAACACACACCATACtacgaaaaaggagcgatac c" /listShort="nsrR" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1015527) /Source="Nicolas_upshifts" /id="U740" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=189 /SigmaFactorBS="agtctcactcgggcaagaaaaaattcccccggcacattcatc TGTTTGCttattggataagtGGGTAAACACACACCATACtacgaaaaaggagcgatac c" /listShort="nsrR" /GFF_Attribute="listLong" promotor_-35 complement(1015539..1015545) /Source="Nicolas_upshift_promotors" /id="U740" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=189 /SigmaFactorBS="agtctcactcgggcaagaaaaaattcccccggcacattcatc TGTTTGCttattggataagtGGGTAAACACACACCATACtacgaaaaaggagcgatac c" /listShort="nsrR" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1015588..1015593 /Source="Nicolas_upshift_promotors" /id="U741" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1163 /SigmaFactorBS="gaattttttcttgcccgagtgagactATCATCttttgtctgg cgggcTCATACATTATAGATAAGTccaagtaggggggattcggttgaacgcggaggag a" /listShort="spoVR" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1015609..1015627 /Source="Nicolas_upshift_promotors" /id="U741" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1163 /SigmaFactorBS="gaattttttcttgcccgagtgagactATCATCttttgtctgg cgggcTCATACATTATAGATAAGTccaagtaggggggattcggttgaacgcggaggag a" /listShort="spoVR" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1015622 /Source="Nicolas_upshifts" /id="U741" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1163 /SigmaFactorBS="gaattttttcttgcccgagtgagactATCATCttttgtctgg cgggcTCATACATTATAGATAAGTccaagtaggggggattcggttgaacgcggaggag a" /listShort="spoVR" /GFF_Attribute="listLong" CDS 1015647..1017053 /gene="spoVR" /locus_tag="BSU_09400" /old_locus_tag="BSU09400" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:8144469, 14680823" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8144469, 14680823; Product type ph: phenotype" /codon_start=1 /transl_table=11 /product="involved in spore cortex synthesis (stage V sporulation, conserved in non sporulating bacteria" /protein_id="NP_388821.1" /db_xref="EnsemblGenomes-Gn:BSU09400" /db_xref="EnsemblGenomes-Tr:CAB12779" /db_xref="GOA:P37875" /db_xref="InterPro:IPR007390" /db_xref="SubtiList:BG10182" /db_xref="UniProtKB/Swiss-Prot:P37875" /translation="MNAEEKKGLQRAIEEITEIAKGFGLDFYPMRYEICPAEIIYTFG AYGMPTRFSHWSFGKQFHKMKLHYDLGLSKIYELVINSDPCYAFLLDSNSLIQNKLIV AHVLAHCDFFKNNCRFQNTKRDMVESMAATAERIKHYEQVHGIKEVESFLDAILSIQE HIDPSLVRPKLQWSVDDEEEEIEEAATPYDDLWSLDEKKPKKQVKKSKKPFPPRPEKD ILLFIEEHSRELEPWQRDILTMMREEMLYFWPQLETKIMNEGWASYWHQRIIRELDLT SDEAIEFAKLNAGVVQPSKTGINPYYLGLKIFEDIEKRYNNPTEEMKKMGVQPDSGRE KMFEVREIESDISFIRNYLTKELVMREDLYLFQKQGRDYKIIDKQWKSVRDQLVSMRV NGGFPYLTVNDGDYMKNNELYIKHWYEGIELDLKYLEKVLPYLFQLWGRSVHIESVLE DKEVMFSYDGKGVHRRYL*" gene 1015647..1017053 /gene="spoVR" /locus_tag="BSU_09400" /old_locus_tag="BSU09400" downshifts 1017033 /Source="Nicolas_upshifts" /id="D490" /incds=0 /nref=43 /ntot=84 /MaxReadThrough="1.30719" /MaxDrop="6.74388" /score="26.4488835" /energy="-11.5" /TU="NA" /idTUdmin="U741" /TUdmin=0 /isTUend="TRUE" CDS complement(1017083..1018468) /gene="phoA" /locus_tag="BSU_09410" /old_locus_tag="BSU09410" /EC_number="3.1.3.1" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:8830275, 10913081, 12897025, 16491025" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8830275, 10913081, 12897025, 16491025; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="alkaline phosphatase A" /protein_id="NP_388822.2" /db_xref="EnsemblGenomes-Gn:BSU09410" /db_xref="EnsemblGenomes-Tr:CAB12780" /db_xref="GOA:P19406" /db_xref="InterPro:IPR001952" /db_xref="InterPro:IPR017849" /db_xref="InterPro:IPR017850" /db_xref="InterPro:IPR018299" /db_xref="SubtiList:BG10183" /db_xref="UniProtKB/Swiss-Prot:P19406" /translation="MKKMSLFQNMKSKLLPIAAVSVLTAGIFAGAELQQTEKASAKKQ DKAEIRNVIVMIGDGMGTPYIRAYRSMKNNGDTPNNPKLTEFDRNLTGMMMTHPDDPD YNITDSAAAGTALATGVKTYNNAIGVDKNGKKVKSVLEEAKQQGKSTGLVATSEINHA TPAAYGAHNESRKNMDQIANSYMDDKIKGKHKIDVLLGGGKSYFNRKDRNLTKEFKQA GYSYVTTKQALKKNKDQQVLGLFADGGLAKALDRDSKTPSLKDMTVSAIDRLNQNKKG FFLMVEGSQIDWAAHDNDTVGAMSEVKDFEQAYKAAIEFAKKDKHTLVIATADHTTGG FTIGANGEKNWHAEPILSAKKTPEFMAKKISEGKPVKDVLARYANLKVTSEEIKSVEA AAQADKSKGASKAIIKIFNTRSNSGWTSTDHTGEEVPVYAYGPGKEKFRGLINNTDQA NIIFKILKTGK*" gene complement(1017083..1018468) /gene="phoA" /locus_tag="BSU_09410" /old_locus_tag="BSU09410" downshifts complement(1017109) /Source="Nicolas_upshifts" /id="D491" /incds=0 /nref=51 /ntot=178 /MaxReadThrough="1.90638" /MaxDrop="5.795" /score="22.2126775" /energy="-13.2" /TU="NA" /idTUdmin="U742" /TUdmin=0 /isTUend="TRUE" upshifts complement(1018495) /Source="Nicolas_upshifts" /id="U742" /multdbtbs="SigA" /comp="M6" /sig="Sig-" /pcomp="0.94105894105894" /psig="0.035964035964036" /xcortree=8 /SigmaFactorBS="acaaggctttacttattgtttacatgatcaacagccgcaTTT AACAAAGTTtccctaacatgataaacggaatacattaaaggaggcatgaaaaaaatga g" /listShort="phoA" /GFF_Attribute="listLong" S_feature complement(1018497..1020028) /Source="Nicolas_S_feature" /locus_tag="new_1018497_1020028_c" /HighExp="Etha, Salt, B60, Heat, M9-stat, T5.0H, T0.30H, T4.0H, T3.30H, T2.30H" /AntisenseName="lytE" /AntisenseCor="-0.65081062481616203" /AntisenseRegPval="-33.1" /CDS_PredictionProba="NA" /TUshortSig="SigWXY, SigA" /TUshortPSig="0.966, 0.992" /TUlongSig="NA" /TUlongPSig="NA" /label="S327" misc_feature complement(1018505..1018516) /Source="Nicolas_upshift_promotors" /id="U742" /multdbtbs="SigA" /comp="M6" /sig="Sig-" /pcomp="0.94105894105894" /psig="0.035964035964036" /xcortree=8 /SigmaFactorBS="acaaggctttacttattgtttacatgatcaacagccgcaTTT AACAAAGTTtccctaacatgataaacggaatacattaaaggaggcatgaaaaaaatga g" /listShort="phoA" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" promotor_-35 1018624..1018631 /Source="Nicolas_upshift_promotors" /id="U743" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.564435564435564" /psig="0.999000999001" /xcortree=3050 /SigmaFactorBS="ttatttgatgtaaagcattcatttttcagaaaaaTCTTTACC tctctgtctttgCATGATATGTTTGTTTAAATaaaaaaactgcggataaccacagctc t" /listShort="S328, lytE" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1018644..1018663 /Source="Nicolas_upshift_promotors" /id="U743" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.564435564435564" /psig="0.999000999001" /xcortree=3050 /SigmaFactorBS="ttatttgatgtaaagcattcatttttcagaaaaaTCTTTACC tctctgtctttgCATGATATGTTTGTTTAAATaaaaaaactgcggataaccacagctc t" /listShort="S328, lytE" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 1018650..1018937 /Source="Nicolas_S_feature" /locus_tag="new_1018650_1018937" /HighExp="T-5.40H, Cold, LoTm, T-4.40H, UNK1, T5.0H, GM-0.1, T3.30H, S1, T4.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S328" upshifts 1018650 /Source="Nicolas_upshifts" /id="U743" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.564435564435564" /psig="0.999000999001" /xcortree=3050 /SigmaFactorBS="ttatttgatgtaaagcattcatttttcagaaaaaTCTTTACC tctctgtctttgCATGATATGTTTGTTTAAATaaaaaaactgcggataaccacagctc t" /listShort="S328, lytE" /GFF_Attribute="listLong" promotor_-35 1018900..1018903 /Source="Nicolas_upshift_promotors" /id="U744" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.75924075924076" /psig="0.971028971028971" /xcortree=3027 /SigmaFactorBS="atttgtcacatgaagtcaagaCTATttctgatgggaatcTAT CCTTATAATAGAAATCAataagattaatttaaaaaaagagatacatatatatagagtt a" /listShort="lytE" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1018918..1018937 /Source="Nicolas_upshift_promotors" /id="U744" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.75924075924076" /psig="0.971028971028971" /xcortree=3027 /SigmaFactorBS="atttgtcacatgaagtcaagaCTATttctgatgggaatcTAT CCTTATAATAGAAATCAataagattaatttaaaaaaagagatacatatatatagagtt a" /listShort="lytE" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1018939 /Source="Nicolas_upshifts" /id="U744" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.75924075924076" /psig="0.971028971028971" /xcortree=3027 /SigmaFactorBS="atttgtcacatgaagtcaagaCTATttctgatgggaatcTAT CCTTATAATAGAAATCAataagattaatttaaaaaaagagatacatatatatagagtt a" /listShort="lytE" /GFF_Attribute="listLong" CDS 1018998..1020002 /gene="lytE" /locus_tag="BSU_09420" /old_locus_tag="BSU09420" /EC_number="3.4.-.-" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:16855244, 16950129, 9457885, 21541672, 22139507, 27002131" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16855244, 16950129, 9457885, 21541672, 22139507, 27002131; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="cell wall dl-endopeptidase; phosphatase-associated protein (major autolysin)" /protein_id="NP_388823.2" /db_xref="EnsemblGenomes-Gn:BSU09420" /db_xref="EnsemblGenomes-Tr:CAB12781" /db_xref="GOA:P54421" /db_xref="InterPro:IPR000064" /db_xref="InterPro:IPR018392" /db_xref="InterPro:IPR036779" /db_xref="SubtiList:BG11406" /db_xref="UniProtKB/Swiss-Prot:P54421" /translation="MKKQIITATTAVVLGSTLFAGAASAQSIKVKKGDTLWDLSRKYD TTISKIKSENHLRSDIIYVGQTLSINGKSTSSKSSSSSSSSSTYKVKSGDSLWKISKK YGMTINELKKLNGLKSDLLRVGQVLKLKGSTSSSSSSSSKVSSSSTSTYKVKSGDSLS KIASKYGTTVSKLKSLNGLKSDVIYVNQVLKVKGTSTSSSKPASSSSSSSSKTSSTSL NVSKLVSDAKALVGTPYKWGGTTTSGFDCSGFIWYVLNKQTSVGRTSTAGYWSSMKSI ASPSVGDFVFFTTYKSGPSHMGIYIGNNSFIHAGSDGVQISSLNNSYWKPRYLGAKRF *" gene 1018998..1020002 /gene="lytE" /locus_tag="BSU_09420" /old_locus_tag="BSU09420" downshifts 1019864 /Source="Nicolas_upshifts" /id="D492" /incds=1 /nref=1 /ntot=117 /MaxReadThrough="6.89938" /MaxDrop="2.1687" /score="26.3320532" /energy="-9.8" /TU="U743,U744" /idTUdmin="U743" /TUdmin="-132" /isTUend="FALSE" downshifts 1019994 /Source="Nicolas_upshifts" /id="D493" /incds=0 /nref=53 /ntot=190 /MaxReadThrough="3.64545" /MaxDrop="6.08377" /score="26.3320532" /energy="-9.8" /TU="U744" /idTUdmin="U743" /TUdmin="-2" /isTUend="TRUE" upshifts complement(1020028) /Source="Nicolas_upshifts" /id="U745" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp="0.966033966033966" /psig="0.966033966033966" /xcortree=1640 /SigmaFactorBS="acattttcatttttaggAGCAACCAAAacgcctgtgctCCGT CTAATGAAAAAAacccgttccaatgaacgggttttctctaaaaattagaatcttttcg c" /listShort="S327, phoA" /GFF_Attribute="listLong" promotor_-10 complement(1020035..1020050) /Source="Nicolas_upshift_promotors" /id="U745" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp="0.966033966033966" /psig="0.966033966033966" /xcortree=1640 /SigmaFactorBS="acattttcatttttaggAGCAACCAAAacgcctgtgctCCGT CTAATGAAAAAAacccgttccaatgaacgggttttctctaaaaattagaatcttttcg c" /listShort="S327, phoA" /GFF_Attribute="listLong" /label="promotor_-10" downshifts 1020040 /Source="Nicolas_upshifts" /id="D494" /incds=0 /nref=1 /ntot=47 /MaxReadThrough="2.99" /MaxDrop="3.76174" /score="26.3320532" /energy="-9.8" /TU="U744" /idTUdmin="U743" /TUdmin=44 /isTUend="FALSE" promotor_-35 complement(1020062..1020071) /Source="Nicolas_upshift_promotors" /id="U745" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp="0.966033966033966" /psig="0.966033966033966" /xcortree=1640 /SigmaFactorBS="acattttcatttttaggAGCAACCAAAacgcctgtgctCCGT CTAATGAAAAAAacccgttccaatgaacgggttttctctaaaaattagaatcttttcg c" /listShort="S327, phoA" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(1020073..1020948) /gene="citR" /locus_tag="BSU_09430" /old_locus_tag="BSU09430" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:8045899, 10869065" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8045899, 10869065; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator CitR (LysR family)" /protein_id="NP_388824.2" /db_xref="EnsemblGenomes-Gn:BSU09430" /db_xref="EnsemblGenomes-Tr:CAB12782" /db_xref="GOA:P39127" /db_xref="InterPro:IPR000847" /db_xref="InterPro:IPR005119" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG10853" /db_xref="UniProtKB/Swiss-Prot:P39127" /translation="MDFKWLHTFVTAAKYENFRKTAETLFLSQPTVTVHIKQLEKEIS CKLFERKGRQIQLTDEGRAYLPYALRLLDDYENSMAELHRVRQGYSQTLQLAVSPLIA DTVLPSVMKRYTAMNTETEMAVTIFESAEIASLIKAGEADIGLSCLKVQSSSLSCHCL YKDPVVLVAPPDKRFIEDNEIDAKEVLEQYLLLTHNHPDYWDDLLRQVRMTFPFVRTM KVTQTHITKRFIKEGLGVSFLPLSTVKRELAEKQMIRIPYQSVQLPYAGAYAIALYEN KKEKKFLDFLSHFHF*" gene complement(1020073..1020948) /gene="citR" /locus_tag="BSU_09430" /old_locus_tag="BSU09430" promotor_-35 1021001..1021002 /Source="Nicolas_upshift_promotors" /id="U747" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.424575424575425" /psig="0.995004995004995" /xcortree=3081 /SigmaFactorBS="atatttttaattaattccctttaaaatattgaTTatttttta aatattatATTTACTATAATAACAGAAAaggatagggggaatacaaatggtacattac g" /listShort="citA, yhdF" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(1021014..1021033) /Source="Nicolas_upshift_promotors" /id="U746" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.387612387612388" /psig="0.992007992007992" /xcortree=1894 /SigmaFactorBS="tccctttaatccgtaatgtaccatttgTATTCCccctatcct tttctGTTATTATAGTAAATATAATatttaaaaaataatcaatattttaaagggaatt a" /listShort="citR, S327" /listLong="phoA" /label="promotor_-10" promotor_-10 1021019..1021038 /Source="Nicolas_upshift_promotors" /id="U747" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.424575424575425" /psig="0.995004995004995" /xcortree=3081 /SigmaFactorBS="atatttttaattaattccctttaaaatattgaTTatttttta aatattatATTTACTATAATAACAGAAAaggatagggggaatacaaatggtacattac g" /listShort="citA, yhdF" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1021020) /Source="Nicolas_upshifts" /id="U746" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.387612387612388" /psig="0.992007992007992" /xcortree=1894 /SigmaFactorBS="tccctttaatccgtaatgtaccatttgTATTCCccctatcct tttctGTTATTATAGTAAATATAATatttaaaaaataatcaatattttaaagggaatt a" /listShort="citR, S327" /listLong="phoA" upshifts 1021029 /Source="Nicolas_upshifts" /id="U747" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.424575424575425" /psig="0.995004995004995" /xcortree=3081 /SigmaFactorBS="atatttttaattaattccctttaaaatattgaTTatttttta aatattatATTTACTATAATAACAGAAAaggatagggggaatacaaatggtacattac g" /listShort="citA, yhdF" /GFF_Attribute="listLong" promotor_-35 complement(1021048..1021053) /Source="Nicolas_upshift_promotors" /id="U746" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.387612387612388" /psig="0.992007992007992" /xcortree=1894 /SigmaFactorBS="tccctttaatccgtaatgtaccatttgTATTCCccctatcct tttctGTTATTATAGTAAATATAATatttaaaaaataatcaatattttaaagggaatt a" /listShort="citR, S327" /listLong="phoA" /label="promotor_-35" CDS 1021057..1022157 /gene="citA" /locus_tag="BSU_09440" /old_locus_tag="BSU09440" /EC_number="2.3.3.16" /function="16.2: Construct biomass (Anabolism)" /function="16.10: Respire" /experiment="publication(s) with functional evidences, PMID:4211224, 8045898, 8045899" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 4211224, 8045898, 8045899; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="citrate synthase I" /protein_id="NP_388825.2" /db_xref="EnsemblGenomes-Gn:BSU09440" /db_xref="EnsemblGenomes-Tr:CAB12783" /db_xref="GOA:P39119" /db_xref="InterPro:IPR002020" /db_xref="InterPro:IPR016142" /db_xref="InterPro:IPR016143" /db_xref="InterPro:IPR019810" /db_xref="InterPro:IPR024176" /db_xref="InterPro:IPR036969" /db_xref="PDB:2C6X" /db_xref="SubtiList:BG10854" /db_xref="UniProtKB/Swiss-Prot:P39119" /translation="MVHYGLKGITCVETSISHIDGEKGRLIYRGHHAKDIALNHSFEE AAYLILFGKLPSTEELQVFKDKLAAERNLPEHIERLIQSLPNNMDDMSVLRTVVSALG ENTYTFHPKTEEAIRLIAITPSIIAYRKRWTRGEQAIAPSSQYGHVENYYYMLTGEQP SEAKKKALETYMILATEHGMNASTFSARVTLSTESDLVSAVTAALGTMKGPLHGGAPS AVTKMLEDIGEKEHAEAYLKEKLEKGERLMGFGHRVYKTKDPRAEALRQKAEEVAGND RDLDLALHVEAEAIRLLEIYKPGRKLYTNVEFYAAAVMRAIDFDDELFTPTFSASRMV GWCAHVLEQAENNMIFRPSAQYTGAIPEEVLS*" gene 1021057..1022157 /gene="citA" /locus_tag="BSU_09440" /old_locus_tag="BSU09440" promotor_-35 1022168..1022174 /Source="Nicolas_upshift_promotors" /id="U748" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp="0.994005994005994" /psig="0.994005994005994" /xcortree=256 /SigmaFactorBS="attcccgaggaagttctttcataacatattttggCGTTTATt catttctgtcgtgTGGTAACGTTCAGTATCAAccacatgtctaggagtgatgaatgtg a" /listShort="yhdF, S329, ctrA, yhdH" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1022189..1022207 /Source="Nicolas_upshift_promotors" /id="U748" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp="0.994005994005994" /psig="0.994005994005994" /xcortree=256 /SigmaFactorBS="attcccgaggaagttctttcataacatattttggCGTTTATt catttctgtcgtgTGGTAACGTTCAGTATCAAccacatgtctaggagtgatgaatgtg a" /listShort="yhdF, S329, ctrA, yhdH" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1022194 /Source="Nicolas_upshifts" /id="U748" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp="0.994005994005994" /psig="0.994005994005994" /xcortree=256 /SigmaFactorBS="attcccgaggaagttctttcataacatattttggCGTTTATt catttctgtcgtgTGGTAACGTTCAGTATCAAccacatgtctaggagtgatgaatgtg a" /listShort="yhdF, S329, ctrA, yhdH" /GFF_Attribute="listLong" CDS 1022231..1023100 /gene="yhdF" /locus_tag="BSU_09450" /old_locus_tag="BSU09450" /EC_number="1.-.-.-" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 10482513, 18643936; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative NAD(P)-dependent dehydrogenase" /protein_id="NP_388826.1" /db_xref="EnsemblGenomes-Gn:BSU09450" /db_xref="EnsemblGenomes-Tr:CAB12784" /db_xref="GOA:O07575" /db_xref="InterPro:IPR002347" /db_xref="InterPro:IPR020904" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG13012" /db_xref="UniProtKB/Swiss-Prot:O07575" /translation="MNPMDRQTEGQEPQHQDRQPGIESKMNPLPLSEDEDYRGSGKLK GKVAIITGGDSGIGRAAAIAFAKEGADISILYLDEHSDAEETRKRIEKENVRCLLIPG DVGDENHCEQAVQQTVDHFGKLDILVNNAAEQHPQDSILNISTEQLEKTFRTNIFSMF HMTKKALPHLQEGCAIINTTSITAYEGDTALIDYSSTKGAIVSFTRSMAKSLADKGIR VNAVAPGPIWTPLIPATFPEEKVKQHGLDTPMGRPGQPVEHAGAYVLLASDESSYMTG QTIHVNGGRFIST*" gene 1022231..1023100 /gene="yhdF" /locus_tag="BSU_09450" /old_locus_tag="BSU09450" downshifts 1023108 /Source="Nicolas_upshifts" /id="D495" /incds=0 /nref=27 /ntot=130 /MaxReadThrough="8.65426" /MaxDrop="6.48064" /score="18.1511963" /energy="-8.2" /TU="U748" /idTUdmin="U747" /TUdmin=9 /isTUend="TRUE" promotor_-35 1023185..1023188 /Source="Nicolas_upshift_promotors" /id="U749" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.597402597402597" /psig="0.998001998001998" /xcortree=2903 /SigmaFactorBS="tgaaaaatttcaaaataaaaaatttgtcgatttttctaacaa tttTGTTttcatttttgcaatTTTATATATAATATTGAGTAggagaaaggaatgattc g" /listShort="S329, ctrA" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 1023200 /Source="Nicolas_upshifts" /id="U749" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.597402597402597" /psig="0.998001998001998" /xcortree=2903 /SigmaFactorBS="tgaaaaatttcaaaataaaaaatttgtcgatttttctaacaa tttTGTTttcatttttgcaatTTTATATATAATATTGAGTAggagaaaggaatgattc g" /listShort="S329, ctrA" /GFF_Attribute="listLong" promotor_-10 1023203..1023222 /Source="Nicolas_upshift_promotors" /id="U749" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.597402597402597" /psig="0.998001998001998" /xcortree=2903 /SigmaFactorBS="tgaaaaatttcaaaataaaaaatttgtcgatttttctaacaa tttTGTTttcatttttgcaatTTTATATATAATATTGAGTAggagaaaggaatgattc g" /listShort="S329, ctrA" /GFF_Attribute="listLong" /label="promotor_-10" misc_feature 1023248..1023267 /Source="Nicolas_upshift_promotors" /id="U750" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.509490509490509" /psig="0.522477522477522" /xcortree=652 /SigmaFactorBS="tttttgcaattttatatataatattgagtaggagaaaggaat gattcgcgaccagTACAAATATAGTAGAAAAAAaagaataatgaccattgttactcat g" /listShort="S329, ctrA" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" S_feature 1023253..1023349 /Source="Nicolas_S_feature" /locus_tag="new_1023253_1023349" /HighExp="Etha, T2.30H, T-0.40H, T2.0H, T1.30H, S1, GM-0.2, T3.0H, T-1.40H, M9-stat" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.27332800000000002" /TUshortSig="SigA, SigA, SigB" /TUshortPSig="0.522, 0.998, 0.994" /TUlongSig="NA" /TUlongPSig="NA" /label="S329" upshifts 1023253 /Source="Nicolas_upshifts" /id="U750" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.509490509490509" /psig="0.522477522477522" /xcortree=652 /SigmaFactorBS="tttttgcaattttatatataatattgagtaggagaaaggaat gattcgcgaccagTACAAATATAGTAGAAAAAAaagaataatgaccattgttactcat g" /listShort="S329, ctrA" /GFF_Attribute="listLong" CDS 1023350..1024747 /gene="bcaP" /locus_tag="BSU_09460" /old_locus_tag="BSU09460" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:15849754, 16621821, 16850406, 21097623, 25645558" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15849754, 16621821, 16850406, 21097623, 25645558; Product type t : transporter" /codon_start=1 /transl_table=11 /product="branched-chain amino acid transporter or methylthioribose-degradation metabolite exporter" /protein_id="NP_388827.1" /db_xref="EnsemblGenomes-Gn:BSU09460" /db_xref="EnsemblGenomes-Tr:CAB12785" /db_xref="GOA:O07576" /db_xref="InterPro:IPR002293" /db_xref="InterPro:IPR004758" /db_xref="SubtiList:BG13013" /db_xref="UniProtKB/Swiss-Prot:O07576" /translation="MKGSVFRKKSIQDLIAATSGEKSLKRELGAFDLTLLGIGAIIGT GIFVLTGTGAVTAGPGLTISFVVAALACLFAALSYAEFASSVPVSGSVYTFTYATLGE LMAFIIGWDLILEYMLAVSAVSVGWSGYFQSFLSGLGIHLPVALTAAPGAVKGTFTLF NLPAFVIVMAITYLLYLGIKESKRVNNIMVILKILVVLLFIAVAAVYVKPHNWQPFMP MGFGGVFSAAALVFFAFIGFDAVSSAAEETKNPAKDLPKGIIFSLLVCTILYVTVSAI MTGVIPFAQFAGVDHPVSLVLQSAGQNWVAGIIDIGAVLGMTTVMLVMLYGQTRVMFA MSRDGLVPGSLSKVHPKHKTPYVATWFFGTMSALLGSLVPLDELAKLVNIGTLSAFVL ISVAVIVLRKKQPDLPRAFKCPGVPVIPGLAILFCLFLILNLGWVTIVRFLVWLLIGL VIYFLYSRKHSKLNQ*" gene 1023350..1024747 /gene="bcaP" /locus_tag="BSU_09460" /old_locus_tag="BSU09460" downshifts 1024727 /Source="Nicolas_upshifts" /id="D496" /incds=0 /nref=116 /ntot=188 /MaxReadThrough="3.41176" /MaxDrop="5.29633" /score="5.08283681" /energy="-12.3" /TU="U748,U749" /idTUdmin="U750" /TUdmin=0 /isTUend="TRUE" promotor_-35 1024808..1024812 /Source="Nicolas_upshift_promotors" /id="U751" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.914085914085914" /psig=1 /xcortree=2512 /SigmaFactorBS="ggccgcctcttttctgttcttggcaaatgaatcTATAGaaat gaagacaaaaaTAAGAGATAATATAGGCTGGaaaggaagtgacgtttattgtctgagc a" /listShort="yhdH" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1024828..1024847 /Source="Nicolas_upshift_promotors" /id="U751" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.914085914085914" /psig=1 /xcortree=2512 /SigmaFactorBS="ggccgcctcttttctgttcttggcaaatgaatcTATAGaaat gaagacaaaaaTAAGAGATAATATAGGCTGGaaaggaagtgacgtttattgtctgagc a" /listShort="yhdH" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1024835 /Source="Nicolas_upshifts" /id="U751" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.914085914085914" /psig=1 /xcortree=2512 /SigmaFactorBS="ggccgcctcttttctgttcttggcaaatgaatcTATAGaaat gaagacaaaaaTAAGAGATAATATAGGCTGGaaaggaagtgacgtttattgtctgagc a" /listShort="yhdH" /GFF_Attribute="listLong" CDS 1024865..1026220 /gene="yhdH" /locus_tag="BSU_09470" /old_locus_tag="BSU09470" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406, 17114254; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative sodium-dependent transporter" /protein_id="NP_388828.1" /db_xref="EnsemblGenomes-Gn:BSU09470" /db_xref="EnsemblGenomes-Tr:CAB12786" /db_xref="GOA:O07577" /db_xref="InterPro:IPR000175" /db_xref="SubtiList:BG13014" /db_xref="UniProtKB/Swiss-Prot:O07577" /translation="MSEQKPVQWASKIGFVMAAAGSAIGLGAIWKFPYVAGTNGGGAF FLIFVLFTILLGYPLLVGEFIFGRRNQTNAIDAYKKEAPRSAWFLTGWIGVAACFLVL SFYSVIGGWILLYIVKTASGSLSGLSQAQYGALFASIIQNPVQTLAAQLVFMALTVLV VARGVQKGIERVSAVMMPILFLLFILLVLRSLTLNGAMEGVKFLLVPHFGDLTPESIL FALGQAFFTLTLGVSVMVTYSSYLPKTQNIPRSAASIVLMNIIVTLLAGLAIFPAVFS FGFQPNEGPTLLFTVLPAVFEQLPFGTLFFIGFLVAFLFAALTSAFSMVEIIVATIGK GDEKKRKKLSWTSGLLIFLVGIPCCLSYGVLSDVHLFGKTFFDIADFTVSNVLMPSGA LLISLFIPLKISKSELLAEMRNGSNAGKAFFYTWFYLLRFIVPLAIIIVFLNLIGILS F*" gene 1024865..1026220 /gene="yhdH" /locus_tag="BSU_09470" /old_locus_tag="BSU09470" downshifts 1026201 /Source="Nicolas_upshifts" /id="D497" /incds=0 /nref=184 /ntot=244 /MaxReadThrough="1.73756" /MaxDrop="6.09379" /score="40.1809389" /energy="-14.8" /TU="NA" /idTUdmin="U751" /TUdmin=0 /isTUend="TRUE" CDS complement(1026255..1027664) /gene="yhdI" /locus_tag="BSU_09480" /old_locus_tag="BSU09480" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15223311; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative PLP-dependent transcriptional regulator" /protein_id="NP_388829.1" /db_xref="EnsemblGenomes-Gn:BSU09480" /db_xref="EnsemblGenomes-Tr:CAB12787" /db_xref="GOA:O07578" /db_xref="InterPro:IPR000524" /db_xref="InterPro:IPR004839" /db_xref="InterPro:IPR015421" /db_xref="InterPro:IPR015422" /db_xref="InterPro:IPR015424" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG13015" /db_xref="UniProtKB/Swiss-Prot:O07578" /translation="MDITPFLDKKSKTPLYEQLYTFFKQEISHARITKGTRLPSKRRL SSLLDVSTATIERAYEQLTAEGYVKSKPKIGWFAAEVEPGFPTAPDHFQQSVQPGLHQ KNAPAIDFHQGSVDPTLFPFNAWRKSIVKSLDRYSGSFHTSGDPQGEYELRHMIARFV RLSRGVNCEPGQIIIGAGTTVLLQNLCLSLKPGTKIGFEEPGFHRSRRMFEANHMDVT PICSDAEGVLPDELYRQNPYLMYTTPSHQFPIGTIMTITRRQELLAWAAETNSFIIED DYDGEFRYSGHPIPSLQGLDPNGRVIYLGTFSKSLLPSLRLSFMIVPPELMEPIQNNV QLMKQTVSAHSQLALADFIETGEWQKHINRMRSLYRKKHAVLLEAIRSELGNTVEILG KNSGLHILLRLLFPASEEEAIQAAADHGVTLYPVSPSYIEQTPFTSVLIGYGGLSEED IRLGIQKLKTAWAPLISSY*" gene complement(1026255..1027664) /gene="yhdI" /locus_tag="BSU_09480" /old_locus_tag="BSU09480" promotor_-35 1027713..1027716 /Source="Nicolas_upshift_promotors" /id="U752" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.52047952047952" /psig="0.996003996003996" /xcortree=459 /SigmaFactorBS="tcctttgtagctggcatggtcattttttctgatattggctAT TTggcaaatgccatttATTAGCTATGATCATTGTAAcgaaaggaaaggggattgagaa g" /listShort="yhdJ" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1027731..1027750 /Source="Nicolas_upshift_promotors" /id="U752" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.52047952047952" /psig="0.996003996003996" /xcortree=459 /SigmaFactorBS="tcctttgtagctggcatggtcattttttctgatattggctAT TTggcaaatgccatttATTAGCTATGATCATTGTAAcgaaaggaaaggggattgagaa g" /listShort="yhdJ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1027733 /Source="Nicolas_upshifts" /id="U752" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.52047952047952" /psig="0.996003996003996" /xcortree=459 /SigmaFactorBS="tcctttgtagctggcatggtcattttttctgatattggctAT TTggcaaatgccatttATTAGCTATGATCATTGTAAcgaaaggaaaggggattgagaa g" /listShort="yhdJ" /GFF_Attribute="listLong" promotor_-10 complement(1027735..1027754) /Source="Nicolas_upshift_promotors" /id="U753" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.583416583416583" /psig=1 /xcortree=2744 /SigmaFactorBS="cttctttcgaggttaattgtttcatatggatcaTCTTCtcaa tcccctttcctTTCGTTACAATGATCATAGCtaataaatggcatttgccaaatagcca a" /listShort="yhdI" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1027747) /Source="Nicolas_upshifts" /id="U753" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.583416583416583" /psig=1 /xcortree=2744 /SigmaFactorBS="cttctttcgaggttaattgtttcatatggatcaTCTTCtcaa tcccctttcctTTCGTTACAATGATCATAGCtaataaatggcatttgccaaatagcca a" /listShort="yhdI" /GFF_Attribute="listLong" promotor_-35 complement(1027770..1027774) /Source="Nicolas_upshift_promotors" /id="U753" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.583416583416583" /psig=1 /xcortree=2744 /SigmaFactorBS="cttctttcgaggttaattgtttcatatggatcaTCTTCtcaa tcccctttcctTTCGTTACAATGATCATAGCtaataaatggcatttgccaaatagcca a" /listShort="yhdI" /GFF_Attribute="listLong" /label="promotor_-35" CDS 1027774..1028202 /gene="yhdJ" /locus_tag="BSU_09490" /old_locus_tag="BSU09490" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 12793527; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative acetyltransferase" /protein_id="NP_388830.1" /db_xref="EnsemblGenomes-Gn:BSU09490" /db_xref="EnsemblGenomes-Tr:CAB12788" /db_xref="GOA:O07579" /db_xref="InterPro:IPR000182" /db_xref="InterPro:IPR016181" /db_xref="SubtiList:BG13016" /db_xref="UniProtKB/Swiss-Prot:O07579" /translation="MIHMKQLTSKEEWAESYPIMSELRTELDIETYLQRLEACVQKES YMLFALYENTAIRALCGALPRVSIHKGEHLWIADLVTTAPCRSKGYGKMLLDYASDWA RKAGLGFVSLSSGLQRKDAHRFYTDKMGFTIESYLFRKPV*" gene 1027774..1028202 /gene="yhdJ" /locus_tag="BSU_09490" /old_locus_tag="BSU09490" downshifts 1028181 /Source="Nicolas_upshifts" /id="D498" /incds=0 /nref=46 /ntot=213 /MaxReadThrough="1.42962" /MaxDrop="4.77191" /score="24.6412105" /energy="-12.1" /TU="NA" /idTUdmin="U752" /TUdmin=0 /isTUend="TRUE" CDS complement(1028233..1028523) /gene="asiMB" /locus_tag="BSU_09500" /old_locus_tag="BSU09500" /experiment="publication(s) with functional evidences, PMID:10216858" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10216858; Product type r: regulator" /codon_start=1 /transl_table=11 /product="negative regulator of the activity of sigma-M" /protein_id="NP_388831.1" /db_xref="EnsemblGenomes-Gn:BSU09500" /db_xref="EnsemblGenomes-Tr:CAB12789" /db_xref="GOA:O07580" /db_xref="InterPro:IPR020496" /db_xref="SubtiList:BG13017" /db_xref="UniProtKB/Swiss-Prot:O07580" /translation="MELVRIFKEHNVFGWISVGTAVLSLLLLNLAIISNVTFYSYQML PFAMAAVPFGVVELFIKRGRTGPGLLGVILNLFVIICVYTIVSVDTNLQFGF*" gene complement(1028233..1028523) /gene="asiMB" /locus_tag="BSU_09500" /old_locus_tag="BSU09500" downshifts complement(1028257) /Source="Nicolas_upshifts" /id="D499" /incds=0 /nref=44 /ntot=229 /MaxReadThrough="2.66153" /MaxDrop="4.72865" /score="26.7359231" /energy="-11.1" /TU="NA" /idTUdmin="U754" /TUdmin=0 /isTUend="TRUE" CDS complement(1028511..1029587) /gene="asiMA" /locus_tag="BSU_09510" /old_locus_tag="BSU09510" /experiment="publication(s) with functional evidences, PMID:10216858" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10216858; Product type r: regulator" /codon_start=1 /transl_table=11 /product="negative regulator of the activity of sigma-M" /protein_id="NP_388832.1" /db_xref="EnsemblGenomes-Gn:BSU09510" /db_xref="EnsemblGenomes-Tr:CAB12790" /db_xref="GOA:O07581" /db_xref="InterPro:IPR025672" /db_xref="InterPro:IPR029101" /db_xref="SubtiList:BG13018" /db_xref="UniProtKB/Swiss-Prot:O07581" /translation="MMNEEFKKRFDQYKNGEMSDQEMTAFEEELEKLEVYQELIDSEL EDDNDWDLSISPEKQKAILAYGKRKSYLRISVLAVISTLMILPLCTLGSYLYYGMGGK HSTGNEFMETAAVTVALTMPNVLVDTSGLKSQVKLFGMNTEFPLQKQIGTKTAAVGNE RVEMFYNKVKAPAVNYYDLEVNKTGHYFTHPSNKSEQTTAKAEKTLSTLPEGTVSEVY LSYDRAYPTKDVYNKFKGYDVSFLWNAIETEKNTNKTASTEPLGYPGKDSKFLAALNT KGKSNGDQFINALKFMSKHEKWAQVISKRKDLNVDNRLDYVEKNGVNVYGSVVTGPTK EIQRMLKNKSVKSANVGEVELWNW*" gene complement(1028511..1029587) /gene="asiMA" /locus_tag="BSU_09510" /old_locus_tag="BSU09510" CDS complement(1029577..1030068) /gene="sigM" /locus_tag="BSU_09520" /old_locus_tag="BSU09520" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:14651641, 14769884" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 14651641, 14769884; Product type r: regulator" /codon_start=1 /transl_table=11 /product="RNA polymerase ECF (extracytoplasmic function)-type sigma factor (sigma(M))" /protein_id="NP_388833.1" /db_xref="EnsemblGenomes-Gn:BSU09520" /db_xref="EnsemblGenomes-Tr:CAB12791" /db_xref="GOA:O07582" /db_xref="InterPro:IPR000838" /db_xref="InterPro:IPR007627" /db_xref="InterPro:IPR013249" /db_xref="InterPro:IPR013324" /db_xref="InterPro:IPR013325" /db_xref="InterPro:IPR014284" /db_xref="InterPro:IPR014296" /db_xref="InterPro:IPR036388" /db_xref="SubtiList:BG13019" /db_xref="UniProtKB/Swiss-Prot:O07582" /translation="MTIDEIYQMYMNDVYRFLLSMTKDKHLAEDLLQETFMRAYIHIH SYDHSKVKPWLFQVARNAFIDYVRKHKKEVTISDDLIGSLFQNAVQSPAHQVEIKEVL TGYMSELPDNYREALTLYYLKELNYKEASHIMNISEANFKSVLFRARQRLKALYNRGV NDE*" gene complement(1029577..1030068) /gene="sigM" /locus_tag="BSU_09520" /old_locus_tag="BSU09520" S_feature complement(1030069..1030171) /Source="Nicolas_S_feature" /locus_tag="new_1030069_1030171_c" /HighExp="Cold, LBGstat, H2O2, G180, Paraq, Oxctl, G135, HPh, dia15, G150" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S330" promotor_-10 complement(1030160..1030179) /Source="Nicolas_upshift_promotors" /id="U754" /multdbtbs="SigA" /comp="M16" /sig="SigA" /pcomp="0.826173826173826" /psig=1 /xcortree=2579 /SigmaFactorBS="ccctctggaaaaaatgttaaacctttctccgcactATCTttt gcggccatttTTGGGTACTATATAGTAATGgtgtttgattaggtataaaaaagccgtt t" /listShort="S330, sigM, yhdL, yhdK" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1030171) /Source="Nicolas_upshifts" /id="U754" /multdbtbs="SigA" /comp="M16" /sig="SigA" /pcomp="0.826173826173826" /psig=1 /xcortree=2579 /SigmaFactorBS="ccctctggaaaaaatgttaaacctttctccgcactATCTttt gcggccatttTTGGGTACTATATAGTAATGgtgtttgattaggtataaaaaagccgtt t" /listShort="S330, sigM, yhdL, yhdK" /GFF_Attribute="listLong" promotor_-35 complement(1030193..1030196) /Source="Nicolas_upshift_promotors" /id="U754" /multdbtbs="SigA" /comp="M16" /sig="SigA" /pcomp="0.826173826173826" /psig=1 /xcortree=2579 /SigmaFactorBS="ccctctggaaaaaatgttaaacctttctccgcactATCTttt gcggccatttTTGGGTACTATATAGTAATGgtgtttgattaggtataaaaaagccgtt t" /listShort="S330, sigM, yhdL, yhdK" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1030209..1030215 /Source="Nicolas_upshift_promotors" /id="U755" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=224 /SigmaFactorBS="tatatagtacccaaaaatggccgcaaaagatagtgcggagaa aGGTTTAAcattttttccagagGGGAAAAGATAGTGAAAAAgtgaaggagtggcacaa t" /listShort="yhdN, plsC" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 1030226 /Source="Nicolas_upshifts" /id="U755" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=224 /SigmaFactorBS="tatatagtacccaaaaatggccgcaaaagatagtgcggagaa aGGTTTAAcattttttccagagGGGAAAAGATAGTGAAAAAgtgaaggagtggcacaa t" /listShort="yhdN, plsC" /GFF_Attribute="listLong" promotor_-10 1030230..1030248 /Source="Nicolas_upshift_promotors" /id="U755" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=224 /SigmaFactorBS="tatatagtacccaaaaatggccgcaaaagatagtgcggagaa aGGTTTAAcattttttccagagGGGAAAAGATAGTGAAAAAgtgaaggagtggcacaa t" /listShort="yhdN, plsC" /GFF_Attribute="listLong" /label="promotor_-10" downshifts complement(1030259) /Source="Nicolas_upshifts" /id="D500" /incds=0 /nref=2 /ntot=13 /MaxReadThrough="2.13683" /MaxDrop="4.59517" /score="8.96845329" /energy="-10.2" /TU="NA" /idTUdmin="U757" /TUdmin=1804 /isTUend="FALSE" CDS 1030265..1031260 /gene="akrN" /locus_tag="BSU_09530" /old_locus_tag="BSU09530" /EC_number="1.1.1.-" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:10220166, 15019785, 24330391" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10220166, 15019785, 24330391; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="aldo/keto reductase specific for NADPH; protectsagainst methylglyoxal" /protein_id="NP_388834.1" /db_xref="EnsemblGenomes-Gn:BSU09530" /db_xref="EnsemblGenomes-Tr:CAB12792" /db_xref="GOA:P80874" /db_xref="InterPro:IPR018170" /db_xref="InterPro:IPR020471" /db_xref="InterPro:IPR023210" /db_xref="InterPro:IPR036812" /db_xref="PDB:1PZ1" /db_xref="SubtiList:BG13020" /db_xref="UniProtKB/Swiss-Prot:P80874" /translation="MEYTSIADTGIEASRIGLGTWAIGGTMWGGTDEKTSIETIRAAL DQGITLIDTAPAYGFGQSEEIVGKAIKEYGKRDQVILATKTALDWKNNQLFRHANRAR IVEEVENSLKRLQTDYIDLYQVHWPDPLVPIEETAEVMKELYDAGKIRAIGVSNFSIE QMDTFRAVAPLHTIQPPYNLFEREMEESVLPYAKDNKITTLLYGSLCRGLLTGKMTEE YTFEGDDLRNHDPKFQKPRFKEYLSAVNQLDKLAKTRYGKSVIHLAVRWILDQPGADI ALWGARKPGQLEALSEITGWTLNSEDQKDINTILENTISDPVGPEFMAPPTREEI*" gene 1030265..1031260 /gene="akrN" /locus_tag="BSU_09530" /old_locus_tag="BSU09530" downshifts 1031239 /Source="Nicolas_upshifts" /id="D501" /incds=0 /nref=59 /ntot=160 /MaxReadThrough="6.85446" /MaxDrop="4.90106" /score="10.4379759" /energy="-11.8" /TU="U755" /idTUdmin="U756" /TUdmin="-770" /isTUend="FALSE" promotor_-35 1031322..1031325 /Source="Nicolas_upshift_promotors" /id="U756" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.537462537462537" /psig=1 /xcortree=2186 /SigmaFactorBS="ctttttggcgtttaaacgagagaaatcttaaaaattaGTACc aggtaataaaaaaTATTGTTATAATAGATGACAgaaagaatcattgattacgacaaag g" /listShort="plsC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1031340..1031359 /Source="Nicolas_upshift_promotors" /id="U756" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.537462537462537" /psig=1 /xcortree=2186 /SigmaFactorBS="ctttttggcgtttaaacgagagaaatcttaaaaattaGTACc aggtaataaaaaaTATTGTTATAATAGATGACAgaaagaatcattgattacgacaaag g" /listShort="plsC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1031345 /Source="Nicolas_upshifts" /id="U756" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.537462537462537" /psig=1 /xcortree=2186 /SigmaFactorBS="ctttttggcgtttaaacgagagaaatcttaaaaattaGTACc aggtaataaaaaaTATTGTTATAATAGATGACAgaaagaatcattgattacgacaaag g" /listShort="plsC" /GFF_Attribute="listLong" CDS 1031395..1031994 /gene="plsC" /locus_tag="BSU_09540" /old_locus_tag="BSU09540" /EC_number="2.3.1.51" /function="16.13: Shape" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:12682299, 1557036, 17557823" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12682299, 1557036, 17557823; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="1-acylglycerol-phosphate (1-acyl-G3P) acyltransferase" /protein_id="NP_388835.1" /db_xref="EnsemblGenomes-Gn:BSU09540" /db_xref="EnsemblGenomes-Tr:CAB12793" /db_xref="GOA:O07584" /db_xref="InterPro:IPR002123" /db_xref="InterPro:IPR004552" /db_xref="SubtiList:BG13021" /db_xref="UniProtKB/Swiss-Prot:O07584" /translation="MYKFCANALKVILSLRGGVKVYNKENLPADSGFVIACTHSGWVD VITLGVGILPYQIHYMAKKELFQNKWIGSFLKKIHAFPVDRENPGPSSIKTPIKLLKE GEIVGIFPSGTRTSEDVPLKRGAVTIAQMGKAPLVPAAYQGPSSGKELFKKGKMKLII GEPLHQADFAHLPSKERLAAMTEALNQRIKELENKLDQL*" gene 1031395..1031994 /gene="plsC" /locus_tag="BSU_09540" /old_locus_tag="BSU09540" downshifts 1032009 /Source="Nicolas_upshifts" /id="D502" /incds=0 /nref=189 /ntot=245 /MaxReadThrough="6.36101" /MaxDrop="7.07164" /score="-7.3088084" /energy="-6.1" /TU="U755" /idTUdmin="U756" /TUdmin=0 /isTUend="TRUE" S_feature 1032054..1034008 /Source="Nicolas_S_feature" /locus_tag="new_1032054_1034008" /HighExp="Cold, C30, S8, T-4.40H, Sw, Fru, S0, S7, HPh, G135" /AntisenseName="yhdP" /AntisenseCor="-0.46228251493795502" /AntisenseRegPval="-14.9" /CDS_PredictionProba="NA" /TUshortSig="NA" /TUshortPSig="NA" /TUlongSig="NA" /TUlongPSig="NA" /label="S331" CDS complement(1032063..1033397) /gene="yhdP" /locus_tag="BSU_09550" /old_locus_tag="BSU09550" /function="16.1: Circulate" /function="16.12: Sense" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 10960106, 25182490; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative magnesium efflux pump" /protein_id="NP_388836.1" /db_xref="EnsemblGenomes-Gn:BSU09550" /db_xref="EnsemblGenomes-Tr:CAB12794" /db_xref="GOA:O07585" /db_xref="InterPro:IPR000644" /db_xref="InterPro:IPR002550" /db_xref="InterPro:IPR005170" /db_xref="InterPro:IPR016169" /db_xref="InterPro:IPR036318" /db_xref="SubtiList:BG13022" /db_xref="UniProtKB/Swiss-Prot:O07585" /translation="MDIVNLILVAVLIALTAFFVASEFAIIRIRGSRIDQLIAEGNKA AIAVKKVTTHLDEYLSACQLGITLTSIGLGVLGESTIERLLHPLFVQMNVPGSLSHVI SFIFAYAIITFLHVVVGELAPKTVAIQKAEAVSMLFAKPLIWFYRIAFPFIWLLNNSA RLLTKAFGLETVSENELAHSEEELRIILSESYKSGEINQSEFKYVNKIFEFDDRLAKE IMIPRTEIVSLPHDIKISEMMDIIQIEKYTRYPVEEGDKDNIIGVINIKEVLTACISG EVSVDSTISQFVNPIIHVIESAPIQDLLVKMQKERVHMAILSDEYGGTAGLVTVEDII EEIVGEIRDEFDIDEISEIRKIGEGHYILDGKVLIDQVNDLLGIHLENEEVDTIGGWF LTQKYDVEKDDSIIEEGCEFIINEIDGHHVAYIEVKKLQEEELLETANQQEA*" gene complement(1032063..1033397) /gene="yhdP" /locus_tag="BSU_09550" /old_locus_tag="BSU09550" downshifts complement(1032082) /Source="Nicolas_upshifts" /id="D503" /incds=0 /nref=284 /ntot=315 /MaxReadThrough="1.96991" /MaxDrop="7.22379" /score="11.1466394" /energy="-9.1" /TU="NA" /idTUdmin="U757" /TUdmin="-19" /isTUend="TRUE" CDS complement(1033458..1033889) /gene="cueR" /locus_tag="BSU_09560" /old_locus_tag="BSU09560" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:14663075, 18048925" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 14663075, 18048925; Product type r: regulator" /codon_start=1 /transl_table=11 /product="indirect copper efflux transcriptional regulator" /protein_id="NP_388837.1" /db_xref="EnsemblGenomes-Gn:BSU09560" /db_xref="EnsemblGenomes-Tr:CAB12795" /db_xref="GOA:O07586" /db_xref="InterPro:IPR000551" /db_xref="InterPro:IPR009061" /db_xref="SubtiList:BG13023" /db_xref="UniProtKB/Swiss-Prot:O07586" /translation="MVGRDIDGAETYRISELAALAGVTKRTVDYYTNLGLLTPARSCS NYRYYDENALKRLIFIVDCKKQRLALSDIKDRLENQFPSSAKLDDEIGNLALEIDHMN QNISGILHRFERLKPEDRDKLKSKLPPEKLAVFQSFMLLLS*" gene complement(1033458..1033889) /gene="cueR" /locus_tag="BSU_09560" /old_locus_tag="BSU09560" promotor_-10 complement(1033901..1033920) /Source="Nicolas_upshift_promotors" /id="U757" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.410589410589411" /psig="0.965034965034965" /xcortree=2994 /SigmaFactorBS="cttccaattccggtctaaaaaaaacaataaACTTGTGcaaga caccgttcaTATATTAAACTATTCTCATAactataacgtgatggttgggagggatata g" /listShort="cueR, yhdP" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1033911) /Source="Nicolas_upshifts" /id="U757" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.410589410589411" /psig="0.965034965034965" /xcortree=2994 /SigmaFactorBS="cttccaattccggtctaaaaaaaacaataaACTTGTGcaaga caccgttcaTATATTAAACTATTCTCATAactataacgtgatggttgggagggatata g" /listShort="cueR, yhdP" /GFF_Attribute="listLong" promotor_-35 complement(1033935..1033941) /Source="Nicolas_upshift_promotors" /id="U757" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.410589410589411" /psig="0.965034965034965" /xcortree=2994 /SigmaFactorBS="cttccaattccggtctaaaaaaaacaataaACTTGTGcaaga caccgttcaTATATTAAACTATTCTCATAactataacgtgatggttgggagggatata g" /listShort="cueR, yhdP" /GFF_Attribute="listLong" /label="promotor_-35" promotor_no_box complement(1033937..1034037) /Source="Nicolas_upshift_promotors" /id="U758" /multdbtbs="-" /comp="M21" /sig="Sig-" /pcomp="0.708291708291708" /psig="0.006993006993007" /xcortree=284 /SigmaFactorBS="tccgcatataaaaatttgaaaattctatcttcctatgttact tcaatcagatgatgaattccacaacttccaattccggtctaaaaaaaacaataaactt g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_no_box" promotor_-35 1033972..1033979 /Source="Nicolas_upshift_promotors" /id="U759" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.616383616383616" /psig="0.996003996003996" /xcortree=3066 /SigmaFactorBS="ttttttagaccggaattggaagTTGTGGAAttcatcatctga tTGAAGTAACATAGGAAGATAgaattttcaaatttttatatgcggaagggacagatga a" /listShort="yhdR, S332" /listLong="S333, yhdT" /label="promotor_-35" upshifts complement(1033977) /Source="Nicolas_upshifts" /id="U758" /multdbtbs="-" /comp="M21" /sig="Sig-" /pcomp="0.708291708291708" /psig="0.006993006993007" /xcortree=284 /SigmaFactorBS="tccgcatataaaaatttgaaaattctatcttcctatgttact tcaatcagatgatgaattccacaacttccaattccggtctaaaaaaaacaataaactt g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 1033993..1034012 /Source="Nicolas_upshift_promotors" /id="U759" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.616383616383616" /psig="0.996003996003996" /xcortree=3066 /SigmaFactorBS="ttttttagaccggaattggaagTTGTGGAAttcatcatctga tTGAAGTAACATAGGAAGATAgaattttcaaatttttatatgcggaagggacagatga a" /listShort="yhdR, S332" /listLong="S333, yhdT" /label="promotor_-10" upshifts 1034010 /Source="Nicolas_upshifts" /id="U759" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.616383616383616" /psig="0.996003996003996" /xcortree=3066 /SigmaFactorBS="ttttttagaccggaattggaagTTGTGGAAttcatcatctga tTGAAGTAACATAGGAAGATAgaattttcaaatttttatatgcggaagggacagatga a" /listShort="yhdR, S332" /listLong="S333, yhdT" CDS 1034046..1035227 /gene="yhdR" /locus_tag="BSU_09570" /old_locus_tag="BSU09570" /EC_number="2.6.-.-" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 12670965, 15103638; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative aspartate aminotransferase" /protein_id="NP_388838.1" /db_xref="EnsemblGenomes-Gn:BSU09570" /db_xref="EnsemblGenomes-Tr:CAB12796" /db_xref="GOA:O07587" /db_xref="InterPro:IPR004838" /db_xref="InterPro:IPR004839" /db_xref="InterPro:IPR015421" /db_xref="InterPro:IPR015422" /db_xref="InterPro:IPR015424" /db_xref="SubtiList:BG13024" /db_xref="UniProtKB/Swiss-Prot:O07587" /translation="MKLAGLSREVEENLNKGSWIRKLFDEGARLKKEFGEDQVFDFSL GNPIVEPPEAFKRALIEEAEKGSHGYIQNQGLLAAREKVAQFLGSRFEADFSAERIVM TVGAGGALNVALKSIVNPGEEVIILAPYFAEYKLYIENYGGKAVSCPLTSRFEIDIEA VRQSITPQTKGLILNTPHNPTGTVLSQKNIDDLGALLKEIEEKSGQTIYVLFDEPYSQ LIYDEELANPFQSYHRVILASSFSKDLGIAGERLGYIGLDSRMPDADLLINAFVYCNR TLGFVNAPVMMQRAVARMDDLRVDASAYKERRDLMVDILKEAGFEFEMPKGGFFVFPK SPIEDEVAFCVHAAQKYKLLIVPSSGFGMSGHFRLSFSVPIEQIKNSRDIFISLYKDF A*" gene 1034046..1035227 /gene="yhdR" /locus_tag="BSU_09570" /old_locus_tag="BSU09570" downshifts 1035212 /Source="Nicolas_upshifts" /id="D504" /incds=0 /nref=12 /ntot=180 /MaxReadThrough="2.81766" /MaxDrop="3.37889" /score="-5.8634451" /energy="-9.1" /TU="U759" /idTUdmin="U759" /TUdmin="-163" /isTUend="FALSE" S_feature 1035257..1035395 /Source="Nicolas_S_feature" /locus_tag="new_1035257_1035395" /HighExp="Etha, S1, BMM, S2, Cold, MG 45, MG 25, C90, T-5.40H, MG 90" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.996" /TUlongSig="NA" /TUlongPSig="NA" /label="S332" misc_feature 1035391..1035410 /Source="Nicolas_upshift_promotors" /id="U760" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.771228771228771" /psig="0.999000999001" /xcortree=460 /SigmaFactorBS="aaggctttcttcatgataaaagtctaaaaattaaaaatcatt tttggaatgagtTGTGTTACAATAAAATATACaatttataatcaaactttgacttttg g" /listShort="S333, yhdT" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" S_feature 1035397..1035553 /Source="Nicolas_S_feature" /locus_tag="new_1035397_1035553" /HighExp="M9-stat, B60, T4.0H, T3.0H, LoTm, S5, T5.0H, S4, T2.30H, T3.30H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.999" /TUlongSig="SigA" /TUlongPSig="0.996" /label="S333" upshifts 1035397 /Source="Nicolas_upshifts" /id="U760" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.771228771228771" /psig="0.999000999001" /xcortree=460 /SigmaFactorBS="aaggctttcttcatgataaaagtctaaaaattaaaaatcatt tttggaatgagtTGTGTTACAATAAAATATACaatttataatcaaactttgacttttg g" /listShort="S333, yhdT" /GFF_Attribute="listLong" CDS 1035554..1036939 /gene="yhdT" /locus_tag="BSU_09590" /old_locus_tag="BSU09590" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative membrane protein" /protein_id="NP_388840.1" /db_xref="EnsemblGenomes-Gn:BSU09590" /db_xref="EnsemblGenomes-Tr:CAB12798" /db_xref="GOA:O07589" /db_xref="InterPro:IPR000644" /db_xref="InterPro:IPR002550" /db_xref="InterPro:IPR005170" /db_xref="InterPro:IPR016169" /db_xref="InterPro:IPR036318" /db_xref="SubtiList:BG13026" /db_xref="UniProtKB/Swiss-Prot:O07589" /translation="MDDIDSLILIGVLIALTAFFVASEFAIVRVRRSRIDQLITEGNK RAILARRVITDLDEYLSASQLGITLTSIGLGVLGEPAFERLLHPLFEPLGLPDSVSHA VSFAVAYGLITFLHVVVGELAPKTVAIQKAEQLTLLIAGPLRLFYLLLFPFIWILNGS ARLLCGMFGLKPASEHDGSHSEEELRMLLSESLKNGEINPSEYKYVNKIFEFDNRIAK EIMIPRKEMAAVSTEMTMAEMLEVMLKEKYTRWPVTDGDKDSVLGLVNTKHLFSDLLF MTEEERMKMTIHPYVRPVIEVIETIPVHDLLIKMQRERIHMAILSDEYGGTSGLVTTE DILEEIVGEIRDEFDEDEQPLIQKLGDGHYVMDGKVRIDQVNSLLGASIQEDVDTIGG LILKENIDIEAGESIRIGSYTIKVLKMDGRLIKQIDIKEEAGNTTGITAHHKLPLPEP VMLNSATLSEK*" gene 1035554..1036939 /gene="yhdT" /locus_tag="BSU_09590" /old_locus_tag="BSU09590" downshifts 1036829 /Source="Nicolas_upshifts" /id="D505" /incds=1 /nref=120 /ntot=240 /MaxReadThrough="5.11037" /MaxDrop="3.79021" /score="19.6985636" /energy="-10.5" /TU="U760" /idTUdmin="U760" /TUdmin="-86" /isTUend="FALSE" downshifts 1036915 /Source="Nicolas_upshifts" /id="D506" /incds=0 /nref=129 /ntot=245 /MaxReadThrough="1.68999" /MaxDrop="6.12682" /score="19.6985636" /energy="-10.5" /TU="NA" /idTUdmin="U760" /TUdmin=0 /isTUend="TRUE" CDS complement(1036953..1037309) /gene="crcBA" /locus_tag="BSU_09600" /old_locus_tag="BSU09600" /function="16.1: Circulate" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 8844142, 12904550, 15849754, 16850406, 17196979, 22194412, 27824896; Product type t: transporter" /codon_start=1 /transl_table=11 /product="fluoride efflux channel component A" /protein_id="NP_388841.1" /db_xref="EnsemblGenomes-Gn:BSU09600" /db_xref="EnsemblGenomes-Tr:CAB12799" /db_xref="GOA:O07590" /db_xref="InterPro:IPR003691" /db_xref="SubtiList:BG13027" /db_xref="UniProtKB/Swiss-Prot:O07590" /translation="MTLAGIFIGGGLGAMLRFWLGNVITAKTKGLSLPIGILTVNILG ALGLGIFTGLHVANASVSLIIGTGFFGAFTTFSTFSVETIQLLMAKRVKESILYIVLT LCGSLFAFWCGWTITI*" gene complement(1036953..1037309) /gene="crcBA" /locus_tag="BSU_09600" /old_locus_tag="BSU09600" CDS complement(1037306..1037701) /gene="crcBB" /locus_tag="BSU_09610" /old_locus_tag="BSU09610" /function="16.1: Circulate" /function="16.4: Excrete" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 8844142, 12904550, 15849754, 16850406, 22194412, 27824896; Product type t : transporter" /codon_start=1 /transl_table=11 /product="subunit of fluoride efflux transporter" /protein_id="NP_388842.1" /db_xref="EnsemblGenomes-Gn:BSU09610" /db_xref="EnsemblGenomes-Tr:CAB12800" /db_xref="GOA:O07591" /db_xref="InterPro:IPR003691" /db_xref="SubtiList:BG13028" /db_xref="UniProtKB/Swiss-Prot:O07591" /translation="MKIYSAVFIGGALGACLRYGLNLWIHTGQFPAATWLENAAGSLL LGILTGFFMIGAKRPLLSAFLGTGFCGGFTTMSTFSKETVMLLQGQPSLALLYVAASL ISGIIFALIGVFVGRRIAGIQQRKGLQEK*" gene complement(1037306..1037701) /gene="crcBB" /locus_tag="BSU_09610" /old_locus_tag="BSU09610" CDS complement(1037688..1038419) /gene="yhdW" /locus_tag="BSU_09620" /old_locus_tag="BSU09620" /EC_number="3.1.4.46" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 8012593; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative glycerophosphodiester phosphodiesterase" /protein_id="NP_388843.1" /db_xref="EnsemblGenomes-Gn:BSU09620" /db_xref="EnsemblGenomes-Tr:CAB12801" /db_xref="GOA:O07592" /db_xref="InterPro:IPR004129" /db_xref="InterPro:IPR017946" /db_xref="InterPro:IPR030395" /db_xref="SubtiList:BG13029" /db_xref="UniProtKB/Swiss-Prot:O07592" /translation="MYIIAHRGASGYAPENTIAAFDLAVKMNADMIELDVQLTKDRQI VVIHDDRVDRTTNGSGFVKDFTLEELQKLDAGSWYGPAFQGERIPTLEAVLKRYHKKI GLLIELKGHPSQVGIEEEVGQLLGQFSFSINNIVQSFQFRSVQRFRELYPSIPTAVIT RPNFGMLSRNQMKAFRSFANYVNIKHTRLNRLMIGSINKNGLNIFAWTVNNQKTAAKL QAMGVDGIVTDYPDFIIKDGKHENI*" gene complement(1037688..1038419) /gene="yhdW" /locus_tag="BSU_09620" /old_locus_tag="BSU09620" misc_feature complement(1038444..1038463) /Source="Nicolas_upshift_promotors" /id="U761" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.683316683316683" /psig="0.986013986013986" /xcortree=3010 /SigmaFactorBS="gcccggaccattccgatatggcagaaaaaattcaccagtttg tatcgcggtgcatatatggaTTTGATACAATAACAGAAATgcccatacgaggagctga c" /listShort="yhdW, yhdV, crcBA" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(1038465) /Source="Nicolas_upshifts" /id="U761" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.683316683316683" /psig="0.986013986013986" /xcortree=3010 /SigmaFactorBS="gcccggaccattccgatatggcagaaaaaattcaccagtttg tatcgcggtgcatatatggaTTTGATACAATAACAGAAATgcccatacgaggagctga c" /listShort="yhdW, yhdV, crcBA" /GFF_Attribute="listLong" promotor_-35 1038512..1038520 /Source="Nicolas_upshift_promotors" /id="U762" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp="0.563436563436563" /psig="0.563436563436563" /xcortree=896 /SigmaFactorBS="atatgcaccgcgatacaaactggtgaattttttctgccatat cGGAATGGTCcgggctgaggaatGCGTATAACTAAAAAAagacactcagcgtatcaga a" /listShort="S334, yhdX" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 1038529 /Source="Nicolas_upshifts" /id="U762" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp="0.563436563436563" /psig="0.563436563436563" /xcortree=896 /SigmaFactorBS="atatgcaccgcgatacaaactggtgaattttttctgccatat cGGAATGGTCcgggctgaggaatGCGTATAACTAAAAAAagacactcagcgtatcaga a" /listShort="S334, yhdX" /GFF_Attribute="listLong" promotor_-10 1038534..1038549 /Source="Nicolas_upshift_promotors" /id="U762" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp="0.563436563436563" /psig="0.563436563436563" /xcortree=896 /SigmaFactorBS="atatgcaccgcgatacaaactggtgaattttttctgccatat cGGAATGGTCcgggctgaggaatGCGTATAACTAAAAAAagacactcagcgtatcaga a" /listShort="S334, yhdX" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 1038543..1038616 /Source="Nicolas_S_feature" /locus_tag="new_1038543_1038616" /HighExp="S5, S4, S6, S7, S8, S3, B60, Pyr, B36, BT" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigWXY" /TUshortPSig="0.563" /TUlongSig="NA" /TUlongPSig="NA" /label="S334" promotor_-35 1038603..1038604 /Source="Nicolas_upshift_promotors" /id="U763" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.937062937062937" /psig="0.998001998001998" /xcortree=461 /SigmaFactorBS="agcgtatcagaacacatttcgtcagaaaattaggtctttcga catGTtcacaacaaaatatgATCCTTTATAATAGCAAAAAaggaggcgagatcatggg a" /listShort="yhdX" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 1038618 /Source="Nicolas_upshifts" /id="U763" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.937062937062937" /psig="0.998001998001998" /xcortree=461 /SigmaFactorBS="agcgtatcagaacacatttcgtcagaaaattaggtctttcga catGTtcacaacaaaatatgATCCTTTATAATAGCAAAAAaggaggcgagatcatggg a" /listShort="yhdX" /GFF_Attribute="listLong" promotor_-10 1038620..1038639 /Source="Nicolas_upshift_promotors" /id="U763" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.937062937062937" /psig="0.998001998001998" /xcortree=461 /SigmaFactorBS="agcgtatcagaacacatttcgtcagaaaattaggtctttcga catGTtcacaacaaaatatgATCCTTTATAATAGCAAAAAaggaggcgagatcatggg a" /listShort="yhdX" /GFF_Attribute="listLong" /label="promotor_-10" CDS 1038653..1038760 /gene="yhdX" /locus_tag="BSU_09630" /old_locus_tag="BSU09630" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_388844.1" /db_xref="EnsemblGenomes-Gn:BSU09630" /db_xref="EnsemblGenomes-Tr:CAB12802" /db_xref="InterPro:IPR035384" /db_xref="SubtiList:BG13030" /db_xref="UniProtKB/Swiss-Prot:O07593" /translation="MGKGRIRVEERIKAETDAEMQKATLLDQTQTKKGK*" gene 1038653..1038760 /gene="yhdX" /locus_tag="BSU_09630" /old_locus_tag="BSU09630" S_feature 1038761..1038814 /Source="Nicolas_S_feature" /locus_tag="new_1038761_1038814" /HighExp="Sw, BC, LPhT, HiOs, S4, HiTm, S5, B36, S7, S6" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="NA" /TUshortPSig="NA" /TUlongSig="NA" /TUlongPSig="NA" /label="S335" downshifts 1038785 /Source="Nicolas_upshifts" /id="D507" /incds=0 /nref=177 /ntot=225 /MaxReadThrough="0.97838" /MaxDrop="7.47175" /score="21.9742676" /energy="-14.5" /TU="NA" /idTUdmin="U762" /TUdmin=0 /isTUend="TRUE" misc_feature 1038865..1038884 /Source="Nicolas_upshift_promotors" /id="U764" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.381618381618382" /psig="0.931068931068931" /xcortree=1800 /SigmaFactorBS="tttcgccggggttttgtgctgcataagacatttaaatgaaca tccttacgaataTTTTAGTATAATAAACAATTgattgggatagaggggagacagtcat g" /listShort="yhdY, yhdZ" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 1038871 /Source="Nicolas_upshifts" /id="U764" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.381618381618382" /psig="0.931068931068931" /xcortree=1800 /SigmaFactorBS="tttcgccggggttttgtgctgcataagacatttaaatgaaca tccttacgaataTTTTAGTATAATAAACAATTgattgggatagaggggagacagtcat g" /listShort="yhdY, yhdZ" /GFF_Attribute="listLong" CDS 1038909..1040024 /gene="mscY" /locus_tag="BSU_09640" /old_locus_tag="BSU09640" /function="16.8: Protect" /function="16.12: Sense" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:12077558, 15849754, 16850406, 17665170, 18310427, 19252899" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12077558, 15849754, 16850406, 17665170, 18310427, 19252899; Product type t : transporter" /codon_start=1 /transl_table=11 /product="small conductance mechano-sensitive channel" /protein_id="NP_388845.1" /db_xref="EnsemblGenomes-Gn:BSU09640" /db_xref="EnsemblGenomes-Tr:CAB12803" /db_xref="GOA:O07594" /db_xref="InterPro:IPR006685" /db_xref="InterPro:IPR006686" /db_xref="InterPro:IPR010920" /db_xref="InterPro:IPR011014" /db_xref="InterPro:IPR011066" /db_xref="SubtiList:BG13031" /db_xref="UniProtKB/Swiss-Prot:O07594" /translation="MPDYLQQYFTLDNIIQIGISLAILLVFLILRKLFTRYFFNLLFN LTNRPKTEIFKQVVLAFDKPARWFFVALGLFLAIRYSPFLDEQMPVISKIYRSLIVAL LCWGLCNLTATSSFIFHKVNQRFELDMDDILAPFLSKLLRFVIIALSVSVIAQEFNYD VNGFVAGLGLGGLAFALAAKDTISNFFGGIIIITEKPFTIGDWVETSTVTGSVEDITF RSTRFRTAQGALVTVPNSTLSMEAITNWTRMTKRQITFSIHVSYATPIENLERSIHSL RTMLLEHEGVDNEIIMVNFDTFADSYYNLFFNFYTKTTVWAENLNIREDINYKIIEIL GAEGVQFAYPGQMVVVKQKHESDQFQVNLNKEEKERA*" gene 1038909..1040024 /gene="mscY" /locus_tag="BSU_09640" /old_locus_tag="BSU09640" downshifts 1040004 /Source="Nicolas_upshifts" /id="D508" /incds=0 /nref=5 /ntot=141 /MaxReadThrough="3.45709" /MaxDrop="3.93891" /score="2.31392404" /energy="-12.3" /TU="U764" /idTUdmin="U764" /TUdmin="-783" /isTUend="FALSE" misc_feature 1040061..1040080 /Source="Nicolas_upshift_promotors" /id="U765" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.937062937062937" /psig=1 /xcortree=3140 /SigmaFactorBS="aaagaggaaaaggaacgggcttaaaagagagacttcgtctga cagaggcggagtctttttCATGGTAAAATAAGAGAAAAaggcggtgttgagttggaaa c" /listShort="yhdZ" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 1040061 /Source="Nicolas_upshifts" /id="U765" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.937062937062937" /psig=1 /xcortree=3140 /SigmaFactorBS="aaagaggaaaaggaacgggcttaaaagagagacttcgtctga cagaggcggagtctttttCATGGTAAAATAAGAGAAAAaggcggtgttgagttggaaa c" /listShort="yhdZ" /GFF_Attribute="listLong" CDS 1040094..1040837 /gene="srtN" /locus_tag="BSU_09650" /old_locus_tag="BSU09650" /EC_number="3.5.1.-" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:16768447, 19136592, 26708127, 27987242" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16768447, 19136592, 26708127, 27987242; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="sirtuin NAD-dependent deacetylase" /protein_id="NP_388846.1" /db_xref="EnsemblGenomes-Gn:BSU09650" /db_xref="EnsemblGenomes-Tr:CAB12804" /db_xref="GOA:O07595" /db_xref="InterPro:IPR003000" /db_xref="InterPro:IPR026590" /db_xref="InterPro:IPR028628" /db_xref="InterPro:IPR029035" /db_xref="SubtiList:BG13032" /db_xref="UniProtKB/Swiss-Prot:O07595" /translation="METFKSILHEAQRIVVLTGAGMSTESGIPDFRSAGGIWTEDASR MEAMSLDYFLSYPRLFWPKFKELFQMKMSGSFEPNEGHLLLAELEKQGKQVDIFTQNI DGLHKKAGSRHVYELHGSIQTAACPACGARYDLPHLLEREVPECTAAGNNGDICGTVL KTDVVLFGDAVMHFDTLYEKLDQADLLLVIGTSLEVAPARFVPEDASLIPGMKKVIIN LEPTYCDSLFDMVIHQKIGEFARSLGMKK*" gene 1040094..1040837 /gene="srtN" /locus_tag="BSU_09650" /old_locus_tag="BSU09650" downshifts 1040809 /Source="Nicolas_upshifts" /id="D509" /incds=0 /nref=3 /ntot=82 /MaxReadThrough="1.93149" /MaxDrop="2.85561" /score="9.76884826" /energy="-9.2" /TU="NA" /idTUdmin="U765" /TUdmin=0 /isTUend="TRUE" CDS complement(1040861..1041709) /gene="yheN" /locus_tag="BSU_09660" /old_locus_tag="BSU09660" /EC_number="3.5.1.-" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative polysaccharide deacetylase" /protein_id="NP_388847.1" /db_xref="EnsemblGenomes-Gn:BSU09660" /db_xref="EnsemblGenomes-Tr:CAB12805" /db_xref="GOA:O07596" /db_xref="InterPro:IPR002509" /db_xref="InterPro:IPR011330" /db_xref="SubtiList:BG13046" /db_xref="UniProtKB/Swiss-Prot:O07596" /translation="MRQTRGEASPSAVSLAFKFASLAVLCVLLLLMVILGYSNSSTKA KEVTVTTNGQLRDEKESLKLKNDSPDLLIKHLQTKQNMGDKTVYLTFDDGPSAVTTRL LDVLKSADVKATFFMLSPRMNEFKQAVKRAEKEGHALGLHGVTHNNRLFYQTPTSPLK EMQEARDTLQDITGYKTDLVRTPYGSKPSLTASQIRNLEKDGFVYWDWTIDSMDWKYR NSQYVTAVLQQLENMEHSSSSRPNVILMHDLPATVNALPVLINKLKEKGYSFGVLEDT MVPVHE*" gene complement(1040861..1041709) /gene="yheN" /locus_tag="BSU_09660" /old_locus_tag="BSU09660" downshifts complement(1040885) /Source="Nicolas_upshifts" /id="D510" /incds=0 /nref=126 /ntot=242 /MaxReadThrough="2.03966" /MaxDrop="4.72968" /score="-7.82934513" /energy="-9.2" /TU="NA" /idTUdmin="U767" /TUdmin=0 /isTUend="TRUE" promotor_-35 1041705..1041710 /Source="Nicolas_upshift_promotors" /id="U766" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1125 /SigmaFactorBS="cgaaactgcagaaggagaagcctctcctctcgtttgtCGCAT AacaatctctccattgGCATAAAATCTCTACATAAtgctgtacagcaggcagcttatg a" /listShort="S337, S338, dat" /GFF_Attribute="listLong" /label="promotor_-35" S_feature complement(1041710..1041809) /Source="Nicolas_S_feature" /locus_tag="new_1041710_1041809_c" /HighExp="Cold, T3.0H, T2.30H, T3.30H, T4.0H, T2.0H, HPh, C30, T1.30H, T5.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S336" promotor_-10 1041726..1041744 /Source="Nicolas_upshift_promotors" /id="U766" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1125 /SigmaFactorBS="cgaaactgcagaaggagaagcctctcctctcgtttgtCGCAT AacaatctctccattgGCATAAAATCTCTACATAAtgctgtacagcaggcagcttatg a" /listShort="S337, S338, dat" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1041728 /Source="Nicolas_upshifts" /id="U766" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1125 /SigmaFactorBS="cgaaactgcagaaggagaagcctctcctctcgtttgtCGCAT AacaatctctccattgGCATAAAATCTCTACATAAtgctgtacagcaggcagcttatg a" /listShort="S337, S338, dat" /GFF_Attribute="listLong" S_feature 1041733..1041928 /Source="Nicolas_S_feature" /locus_tag="new_1041733_1041928" /HighExp="S5, S4, S6, S3, S7, S8, LoTm, B36, T5.0H, B60" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigEF" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S337" promotor_-10 complement(1041798..1041817) /Source="Nicolas_upshift_promotors" /id="U767" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.57042957042957" /psig=1 /xcortree=2149 /SigmaFactorBS="ttttttccttaaaatctgacatttcgacaaattttctATGTg ctttccagttttaTTCCTGTATACTTGACTGGTaatacataggttgtaaacataaggc a" /listShort="S336, yheN" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1041812) /Source="Nicolas_upshifts" /id="U767" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.57042957042957" /psig=1 /xcortree=2149 /SigmaFactorBS="ttttttccttaaaatctgacatttcgacaaattttctATGTg ctttccagttttaTTCCTGTATACTTGACTGGTaatacataggttgtaaacataaggc a" /listShort="S336, yheN" /GFF_Attribute="listLong" promotor_-35 complement(1041832..1041835) /Source="Nicolas_upshift_promotors" /id="U767" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.57042957042957" /psig=1 /xcortree=2149 /SigmaFactorBS="ttttttccttaaaatctgacatttcgacaaattttctATGTg ctttccagttttaTTCCTGTATACTTGACTGGTaatacataggttgtaaacataaggc a" /listShort="S336, yheN" /GFF_Attribute="listLong" /label="promotor_-35" misc_feature 1041927..1041946 /Source="Nicolas_upshift_promotors" /id="U768" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.99100899100899" /psig=1 /xcortree=2940 /SigmaFactorBS="aaataaactcctttccgctatagatctcttgatctttctgtt tttcagcttgtccaaTATGGTAGAATTAGTGATAAtgacagcttgaatgacatcaggg a" /listShort="S338, dat" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" S_feature 1041930..1041993 /Source="Nicolas_S_feature" /locus_tag="new_1041930_1041993" /HighExp="BC, T2.30H, T3.0H, T3.30H, T4.0H, T5.0H, T2.0H, T1.30H, S4, M9-stat" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigEF" /TUshortPSig="1, 0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S338" upshifts 1041930 /Source="Nicolas_upshifts" /id="U768" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.99100899100899" /psig=1 /xcortree=2940 /SigmaFactorBS="aaataaactcctttccgctatagatctcttgatctttctgtt tttcagcttgtccaaTATGGTAGAATTAGTGATAAtgacagcttgaatgacatcaggg a" /listShort="S338, dat" /GFF_Attribute="listLong" CDS 1041994..1042842 /gene="dat" /locus_tag="BSU_09670" /old_locus_tag="BSU09670" /EC_number="2.6.1.21" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 9003455, 17005988; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="D-alanine aminotransferase" /protein_id="NP_388848.1" /db_xref="EnsemblGenomes-Gn:BSU09670" /db_xref="EnsemblGenomes-Tr:CAB12806" /db_xref="GOA:O07597" /db_xref="InterPro:IPR001544" /db_xref="InterPro:IPR005784" /db_xref="InterPro:IPR018300" /db_xref="InterPro:IPR036038" /db_xref="SubtiList:BG13045" /db_xref="UniProtKB/Swiss-Prot:O07597" /translation="MKVLVNGRLIGRSEASIDLEDRGYQFGDGIYEVIRVYKGVLFGL REHAERFFRSAAEIGISLPFSIEDLEWDLQKLVQENAVSEGAVYIQTTRGVAPRKHQY EAGLEPQTTAYTFTVKKPEQEQAYGVAAITDEDLRWLRCDIKSLNLLYNVMTKQRAYE AGAFEAILLRDGVVTEGTSSNVYAVINGTVRTHPANRLILNGITRMNILGLIEKNGIK LDETPVSEEELKQAEEIFISSTTAEIIPVVTLDGQSIGSGKPGPVTKQLQAAFQESIQ QAASIS*" gene 1041994..1042842 /gene="dat" /locus_tag="BSU_09670" /old_locus_tag="BSU09670" downshifts 1042833 /Source="Nicolas_upshifts" /id="D511" /incds=0 /nref=232 /ntot=261 /MaxReadThrough="2.27201" /MaxDrop="6.88888" /score="21.6239924" /energy="-11.5" /TU="U768" /idTUdmin="U766" /TUdmin=0 /isTUend="TRUE" CDS complement(1042885..1044246) /gene="nhaC" /locus_tag="BSU_09680" /old_locus_tag="BSU09680" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:10735849, 11274110, 15849754, 16850406, 17937670" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10735849, 11274110, 15849754, 16850406, 17937670; Product type t : transporter" /codon_start=1 /transl_table=11 /product="Na+/H+ antiporter" /protein_id="NP_388849.1" /db_xref="EnsemblGenomes-Gn:BSU09680" /db_xref="EnsemblGenomes-Tr:CAB12807" /db_xref="GOA:O07553" /db_xref="InterPro:IPR004770" /db_xref="InterPro:IPR018461" /db_xref="SubtiList:BG13044" /db_xref="UniProtKB/Swiss-Prot:O07553" /translation="MDSQKKLTFPLAVGLFIFMLCIIISCLFLLHVEPHIPLFLSVVM LSAAALWFGFPWKSIEKGIVDGIKNGVQPIIVLALIGILIGAWMYSGAIPTMTVYALS FIEPSHLLLTALFSCMIISTLVGSSLTTVSTIGVALIGVASAAGVPLEWTAGAVICGA CFGDKMSPMSDTTNFAAGIGEIPIFEHIRHMMGTTIPALLITVVLFYFLGSSVSADAA STDNIQQVITGIKDAANVTPWALLSPLLVVLLAMKRVSVIPVLTAGIISSGILTAIFV PYSSLQAFMTALQNGTTFETDNEAAAKIINRGGLQSMMGSVSLIMIAFALGGLMEKIG LISALLEGVMKGIRSKGRLVAATVCSSIGVNLATGEQYLSILIPGQSFKSLYDKRNIQ RKFLTRSLEDGGTLINPLIPWGVSGAFMASALGVPVIDYIPFTFFLYISPMISILIGF VKK*" gene complement(1042885..1044246) /gene="nhaC" /locus_tag="BSU_09680" /old_locus_tag="BSU09680" downshifts complement(1042909) /Source="Nicolas_upshifts" /id="D512" /incds=0 /nref=7 /ntot=77 /MaxReadThrough="0.50034" /MaxDrop="3.60175" /score="1.04025421" /energy="-11.5" /TU="NA" /idTUdmin="U769" /TUdmin=22 /isTUend="TRUE" S_feature complement(1044247..1044317) /Source="Nicolas_S_feature" /locus_tag="new_1044247_1044317_c" /HighExp="B60, G135, Etha, LBGexp, G150, Diami, Paraq, G180, H2O2, Gly" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigB" /TUshortPSig="0.96, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S339" misc_feature complement(1044290..1044309) /Source="Nicolas_upshift_promotors" /id="U769" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.926073926073926" /psig="0.96003996003996" /xcortree=2470 /SigmaFactorBS="agtgagcacgccctgtgctcacttcttttatattcataattg tgaaaaaacatagattttcgttttttTCTGTTATAATGCTTTCGTGcccaaaagcaca a" /listShort="S339, nhaC" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(1044317) /Source="Nicolas_upshifts" /id="U769" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.926073926073926" /psig="0.96003996003996" /xcortree=2470 /SigmaFactorBS="agtgagcacgccctgtgctcacttcttttatattcataattg tgaaaaaacatagattttcgttttttTCTGTTATAATGCTTTCGTGcccaaaagcaca a" /listShort="S339, nhaC" /GFF_Attribute="listLong" CDS complement(1044373..1044873) /gene="nhaX" /locus_tag="BSU_09690" /old_locus_tag="BSU09690" /function="16.12: Sense" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1c: Function from experimental evidences in the studied genus; PubMedId: 11988534, 16159758, 27464829; Product type f: factor" /codon_start=1 /transl_table=11 /product="stress response protein, UspA family" /protein_id="NP_388850.2" /db_xref="EnsemblGenomes-Gn:BSU09690" /db_xref="EnsemblGenomes-Tr:CAB12808" /db_xref="GOA:O07552" /db_xref="InterPro:IPR006015" /db_xref="InterPro:IPR006016" /db_xref="InterPro:IPR014729" /db_xref="SubtiList:BG13043" /db_xref="UniProtKB/Swiss-Prot:O07552" /translation="MFHADRIIVAFDGSENSKKALLTAIDLAKTVNAAITVAHSHDMK DNQTVIDPPRPAAEASYISGGMTSVPDPLISDVTSPEPMIYEDRTEEVIAEARMMLNE QQADGDIDILEGDPAESIIEHANRISADMIVTGSRDQNRLKKLIFGSVSEKLSAKSDI PVLIVK*" gene complement(1044373..1044873) /gene="nhaX" /locus_tag="BSU_09690" /old_locus_tag="BSU09690" downshifts complement(1044405) /Source="Nicolas_upshifts" /id="D513" /incds=0 /nref=10 /ntot=63 /MaxReadThrough="4.74071" /MaxDrop="5.69273" /score="4.44189378" /energy="-12.2" /TU="U770" /idTUdmin="U770" /TUdmin="-1320" /isTUend="FALSE" promotor_-10 complement(1044895..1044913) /Source="Nicolas_upshift_promotors" /id="U770" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=208 /SigmaFactorBS="aaacaaaaccttttattgtcaatcattacttgaataggaaaA GGTTAAttgtgctcaaattcGGGTAGTAGTGTTGTAAGAcgctttgaaagggtgagaa g" /listShort="nhaX, S339, nhaC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1044915) /Source="Nicolas_upshifts" /id="U770" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=208 /SigmaFactorBS="aaacaaaaccttttattgtcaatcattacttgaataggaaaA GGTTAAttgtgctcaaattcGGGTAGTAGTGTTGTAAGAcgctttgaaagggtgagaa g" /listShort="nhaX, S339, nhaC" /GFF_Attribute="listLong" promotor_-35 complement(1044928..1044934) /Source="Nicolas_upshift_promotors" /id="U770" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=208 /SigmaFactorBS="aaacaaaaccttttattgtcaatcattacttgaataggaaaA GGTTAAttgtgctcaaattcGGGTAGTAGTGTTGTAAGAcgctttgaaagggtgagaa g" /listShort="nhaX, S339, nhaC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1044952..1044959 /Source="Nicolas_upshift_promotors" /id="U771" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.918081918081918" /psig=1 /xcortree=416 /SigmaFactorBS="ctacccgaatttgagcacaattaaccttttcctattcaagta atGATTGACAataaaaggttttgtTTATATGATGATAAAAAGATgaaatcagaatgga a" /listShort="S340, yheJ, S341, yheI, yheH" /GFF_Attribute="listLong" /label="promotor_-35" S_feature 1044967..1045036 /Source="Nicolas_S_feature" /locus_tag="new_1044967_1045036" /HighExp="C90, M9-stat, BC, T1.30H, T3.30H, Sw, T5.0H, GM 15, T3.0H, T2.30H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S340" upshifts 1044968 /Source="Nicolas_upshifts" /id="U771" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.918081918081918" /psig=1 /xcortree=416 /SigmaFactorBS="ctacccgaatttgagcacaattaaccttttcctattcaagta atGATTGACAataaaaggttttgtTTATATGATGATAAAAAGATgaaatcagaatgga a" /listShort="S340, yheJ, S341, yheI, yheH" /GFF_Attribute="listLong" promotor_-10 1044974..1044993 /Source="Nicolas_upshift_promotors" /id="U771" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.918081918081918" /psig=1 /xcortree=416 /SigmaFactorBS="ctacccgaatttgagcacaattaaccttttcctattcaagta atGATTGACAataaaaggttttgtTTATATGATGATAAAAAGATgaaatcagaatgga a" /listShort="S340, yheJ, S341, yheI, yheH" /GFF_Attribute="listLong" /label="promotor_-10" CDS 1045037..1045198 /gene="bmrB" /locus_tag="BSU_09700" /old_locus_tag="BSU09700" /experiment="publication(s) with functional evidences, PMID:25217586" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 25217586; Product type r: regulator" /codon_start=1 /transl_table=11 /product="regulator leader peptide" /protein_id="NP_388851.1" /db_xref="EnsemblGenomes-Gn:BSU09700" /db_xref="EnsemblGenomes-Tr:CAB12809" /db_xref="SubtiList:BG13042" /db_xref="UniProtKB/Swiss-Prot:O07551" /translation="MFIKQFHIGAANLLFCFRERFFRSDRALKSAVRNISVKKGMELT LHAFFIYKI*" gene 1045037..1045198 /gene="bmrB" /locus_tag="BSU_09700" /old_locus_tag="BSU09700" downshifts 1045128 /Source="Nicolas_upshifts" /id="D514" /incds=1 /nref=29 /ntot=180 /MaxReadThrough="5.31538" /MaxDrop="4.59672" /score="25.6910195" /energy="-14.4" /TU="U771" /idTUdmin="U768" /TUdmin=2273 /isTUend="FALSE" S_feature 1045199..1045317 /Source="Nicolas_S_feature" /locus_tag="new_1045199_1045317" /HighExp="LPhT, S7, S6, T-1.10H, Sw, LBGstat, S5, T-0.40H, S8, T-1.40H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S341" CDS 1045318..1047075 /gene="bmrC" /locus_tag="BSU_09710" /old_locus_tag="BSU09710" /function="16.1: Circulate" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:15855514, 16487324, 19167342, 21602923, 25217586" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15855514, 16487324, 19167342, 21602923, 25217586; Product type t : transporter" /codon_start=1 /transl_table=11 /product="efflux ABC transporter (ATP-binding protein)" /protein_id="NP_388852.1" /db_xref="EnsemblGenomes-Gn:BSU09710" /db_xref="EnsemblGenomes-Tr:CAB12810" /db_xref="GOA:O07550" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR011527" /db_xref="InterPro:IPR017871" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR036640" /db_xref="SubtiList:BG13041" /db_xref="UniProtKB/Swiss-Prot:O07550" /translation="MFSVLKKLGWFFKAYWLRYTIAIVLLLAVNVIEMFPPKLLGNAI DDMKAGAFTAEGLLFYIGIFFVLTAAVYIMSYFWMHQLFGGANLMEKILRTKLMGHLL TMSPPFYEKNRTGDLMARGTNDLQAVSLTTGFGILTLVDSTMFMMTIFLTMGFLISWK LTFAAIIPLPVMAIAISLYGSKIHERFTEAQNAFGALNDRVLESVSGVRVIRAYVQET NDVRRFNEMTADVYQKNMKVAFIDSLFEPTVKLLVGASYLIGLGYGAFLVFRNELTLG ELVSFNVYLGMMIWPMFAIGELINVMQRGNASLDRVNETLSYETDVTDPKQPADLKEP GDIVFSHVSFTYPSSTSDNLQDISFTVRKGQTVGIAGKTGSGKTTIIKQLLRQYPPGE GSITFSGVPIQQIPLDRLRGWIGYVPQDHLLFSRTVKENILYGKQDATDKEVQQAIAE AHFEKDLHMLPSGLETMVGEKGVALSGGQKQRISIARALMANPEILILDDSLSAVDAK TEAAIIKNIRENRKGKTTFILTHRLSAVEHADLILVMDGGVIAERGTHQELLANNGWY REQYERQQLFTAEEGGAGA*" gene 1045318..1047075 /gene="bmrC" /locus_tag="BSU_09710" /old_locus_tag="BSU09710" CDS 1047072..1049093 /gene="bmrD" /locus_tag="BSU_09720" /old_locus_tag="BSU09720" /function="16.1: Circulate" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:15855514, 16487324, 19167342, 21602923, 25217586" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15855514, 16487324, 19167342, 21602923, 25217586; Product type t : transporter" /codon_start=1 /transl_table=11 /product="efflux ABC transporter (ATP-binding subunit)" /protein_id="NP_388853.1" /db_xref="EnsemblGenomes-Gn:BSU09720" /db_xref="EnsemblGenomes-Tr:CAB12811" /db_xref="GOA:O07549" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR011527" /db_xref="InterPro:IPR017871" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR036640" /db_xref="SubtiList:BG13040" /db_xref="UniProtKB/Swiss-Prot:O07549" /translation="MKIGKTLWRYALLYRKLLITAVLLLTVAVGAELTGPFIGKKMID DHILGIEKTWYEAAEKDKNAVQFHGVSYVREDRLQEPVSKAKEAHIYQVGMAFYFVDQ AVSFDGNRTVSDGKLTITNGDKSRAYAAEKLTKQELFQFYQPEIKGMVLLICLYGGLL VFSVFFQYGQHYLLQMSANRIIQKMRQDVFSHIQKMPIRYFDNLPAGKVVARITNDTE AIRDLYVTVLSTFVTSGIYMFGIFTALFLLDVKLAFVCLAIVPIIWLWSVIYRRYASY YNQKIRSINSDINAKMNESIQGMTIIQAFRHQKETMREFEELNESHFYFQNRMLNLNS LMSHNLVNVIRNLAFVCLIWHFGGASLNAAGIVSIGVLYAFVDYLNRLFQPITGIVNQ FSKLELARVSAGRVFELLEEKNTEEAGEPAKERALGRVEFRDVSFAYQEGEEVLKHIS FTAQKGETVALVGHTGSGKSSILNLLFRFYDAQKGDVLIDGKSIYNMSRQELRSHMGI VLQDPYLFSGTIGSNVSLDDERMTEEEIKNALRQVGAEPLLKKLPKGINEPVIEKGST LSSGERQLISFARALAFDPAILILDEATAHIDTETEAVIQKALDVVKQGRTTFVIAHR LSTIRNADQILVLDKGEIVERGNHEELMALEGQYYQMYELQKGQKHSIA*" gene 1047072..1049093 /gene="bmrD" /locus_tag="BSU_09720" /old_locus_tag="BSU09720" downshifts 1049081 /Source="Nicolas_upshifts" /id="D515" /incds=0 /nref=69 /ntot=230 /MaxReadThrough="0.741399999999999" /MaxDrop="5.11492" /score="9.67206405" /energy="-10.9" /TU="NA" /idTUdmin="U771" /TUdmin=0 /isTUend="TRUE" CDS complement(1049142..1049762) /gene="yheG" /locus_tag="BSU_09730" /old_locus_tag="BSU09730" /EC_number="1.-.-.-" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative NADH-flavin oxidoreductase" /protein_id="NP_388854.1" /db_xref="EnsemblGenomes-Gn:BSU09730" /db_xref="EnsemblGenomes-Tr:CAB12812" /db_xref="InterPro:IPR016040" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG13039" /db_xref="UniProtKB/Swiss-Prot:O07548" /translation="MKIALLGASGRVGQAFLTQAAADERFDIFALIRSQHADLPLSKD RTVMGNARRLEDVKKIMENAEIVISCLGTDGDDTLSTAMAHILSVMEEQHIKRLITIG TAGILDSRYEPGKYRFETNESKRKQTRAAKEHAKVYEMLKESSLDWTIICPTYLPDGT ATGVYRTERNVLPEGGTSISVGDTADFLYRELVTGEYVGNRVGLAY*" gene complement(1049142..1049762) /gene="yheG" /locus_tag="BSU_09730" /old_locus_tag="BSU09730" downshifts complement(1049157) /Source="Nicolas_upshifts" /id="D516" /incds=0 /nref=19 /ntot=169 /MaxReadThrough="1.82652" /MaxDrop="3.00293" /score="-0.293143554" /energy="-10.9" /TU="NA" /idTUdmin="U772" /TUdmin=0 /isTUend="TRUE" promotor_no_box 1049747..1049847 /Source="Nicolas_upshift_promotors" /id="U773" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.45954045954046" /psig="0.043956043956044" /xcortree=770 /SigmaFactorBS="ataaagcgattttcattaaaaaacctcctcgcctttcattat aaaaggatgttctcagtttgaacagcgcgggaaagaatacctgtacaaataaacagaa c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_no_box" promotor_-10 complement(1049776..1049795) /Source="Nicolas_upshift_promotors" /id="U772" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.844155844155844" /psig="0.955044955044955" /xcortree=2213 /SigmaFactorBS="catcgttctgtttatttgtacaggtattctttcccgcgCTGT tcaaactgagaacaTCCTTTTATAATGAAAGGCGaggaggttttttaatgaaaatcgc t" /listShort="yheG" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1049791) /Source="Nicolas_upshifts" /id="U772" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.844155844155844" /psig="0.955044955044955" /xcortree=2213 /SigmaFactorBS="catcgttctgtttatttgtacaggtattctttcccgcgCTGT tcaaactgagaacaTCCTTTTATAATGAAAGGCGaggaggttttttaatgaaaatcgc t" /listShort="yheG" /GFF_Attribute="listLong" CDS complement(1049801..1049926) /gene="yheF" /locus_tag="BSU_09740" /old_locus_tag="BSU09740" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_388855.1" /db_xref="EnsemblGenomes-Gn:BSU09740" /db_xref="EnsemblGenomes-Tr:CAB12813" /db_xref="SubtiList:BG13038" /db_xref="UniProtKB/Swiss-Prot:O07547" /translation="MSFITIVNWELVQFVSVSMIHEYVSHRSVYLYRYSFPRCSN*" gene complement(1049801..1049926) /gene="yheF" /locus_tag="BSU_09740" /old_locus_tag="BSU09740" upshifts 1049807 /Source="Nicolas_upshifts" /id="U773" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.45954045954046" /psig="0.043956043956044" /xcortree=770 /SigmaFactorBS="ataaagcgattttcattaaaaaacctcctcgcctttcattat aaaaggatgttctcagtttgaacagcgcgggaaagaatacctgtacaaataaacagaa c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(1049810..1049813) /Source="Nicolas_upshift_promotors" /id="U772" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.844155844155844" /psig="0.955044955044955" /xcortree=2213 /SigmaFactorBS="catcgttctgtttatttgtacaggtattctttcccgcgCTGT tcaaactgagaacaTCCTTTTATAATGAAAGGCGaggaggttttttaatgaaaatcgc t" /listShort="yheG" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(1049940..1049959) /Source="Nicolas_upshift_promotors" /id="U774" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1332 /SigmaFactorBS="agggcgcggtttccgcgctctctttatTTTGTCACCCttttt tcctgctcCACATATCCTAGAAAAAAAGggagggaatcggggtgtcattcatcaccat t" /listShort="yheF" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1049949) /Source="Nicolas_upshifts" /id="U774" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1332 /SigmaFactorBS="agggcgcggtttccgcgctctctttatTTTGTCACCCttttt tcctgctcCACATATCCTAGAAAAAAAGggagggaatcggggtgtcattcatcaccat t" /listShort="yheF" /GFF_Attribute="listLong" promotor_-35 complement(1049973..1049982) /Source="Nicolas_upshift_promotors" /id="U774" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1332 /SigmaFactorBS="agggcgcggtttccgcgctctctttatTTTGTCACCCttttt tcctgctcCACATATCCTAGAAAAAAAGggagggaatcggggtgtcattcatcaccat t" /listShort="yheF" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 1050005 /Source="Nicolas_upshifts" /id="D517" /incds=0 /nref=6 /ntot=22 /MaxReadThrough="0.352760000000001" /MaxDrop="4.67633" /score="9.67206405" /energy="-10.9" /TU="NA" /idTUdmin="U773" /TUdmin=88 /isTUend="FALSE" CDS complement(1050031..1050234) /gene="sspB" /locus_tag="BSU_09750" /old_locus_tag="BSU09750" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:3009398, 9572981, 16707666, 19659696, 26790838" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 3009398, 9572981, 16707666, 19659696, 26790838; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="small acid-soluble spore protein (beta-type SASP)" /protein_id="NP_388856.1" /db_xref="EnsemblGenomes-Gn:BSU09750" /db_xref="EnsemblGenomes-Tr:CAB12814" /db_xref="GOA:P04832" /db_xref="InterPro:IPR001448" /db_xref="InterPro:IPR018126" /db_xref="SubtiList:BG10787" /db_xref="UniProtKB/Swiss-Prot:P04832" /translation="MANQNSSNDLLVPGAAQAIDQMKLEIASEFGVNLGADTTSRANG SVGGEITKRLVSFAQQQMGGRVQ*" gene complement(1050031..1050234) /gene="sspB" /locus_tag="BSU_09750" /old_locus_tag="BSU09750" downshifts complement(1050036) /Source="Nicolas_upshifts" /id="D518" /incds=0 /nref=72 /ntot=93 /MaxReadThrough="1.27819" /MaxDrop="8.55895" /score="22.2113888" /energy="-16" /TU="NA" /idTUdmin="U776" /TUdmin=1 /isTUend="TRUE" S_feature complement(1050235..1050345) /Source="Nicolas_S_feature" /locus_tag="new_1050235_1050345_c" /HighExp="S8, S5, S7, S6, S4, G/S, Pyr, ferm, BT, nit" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigGF" /TUshortPSig="0.996" /TUlongSig="NA" /TUlongPSig="NA" /label="S342" promotor_no_box 1050275..1050375 /Source="Nicolas_upshift_promotors" /id="U775" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.665334665334665" /psig="0.090909090909091" /xcortree=696 /SigmaFactorBS="ggagttgcaccaatctgtgaacccttctcgggtgtcactgcc gcctcggcgtaacccaatgctttgccggcttgttactacgtattatgttaaaatggcc g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_no_box" upshifts 1050335 /Source="Nicolas_upshifts" /id="U775" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.665334665334665" /psig="0.090909090909091" /xcortree=696 /SigmaFactorBS="ggagttgcaccaatctgtgaacccttctcgggtgtcactgcc gcctcggcgtaacccaatgctttgccggcttgttactacgtattatgttaaaatggcc g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" upshifts complement(1050351) /Source="Nicolas_upshifts" /id="U776" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp="0.996003996003996" /psig="0.996003996003996" /xcortree=836 /SigmaFactorBS="ctcaagatttaccacacaattctcCGCATGAttttccggcca tttTAACATAATACGtagtaacaagccggcaaagcattgggttacgccgaggcggcag t" /listShort="S342, sspB" /GFF_Attribute="listLong" promotor_-10 complement(1050355..1050366) /Source="Nicolas_upshift_promotors" /id="U776" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp="0.996003996003996" /psig="0.996003996003996" /xcortree=836 /SigmaFactorBS="ctcaagatttaccacacaattctcCGCATGAttttccggcca tttTAACATAATACGtagtaacaagccggcaaagcattgggttacgccgaggcggcag t" /listShort="S342, sspB" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 complement(1050381..1050387) /Source="Nicolas_upshift_promotors" /id="U776" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp="0.996003996003996" /psig="0.996003996003996" /xcortree=836 /SigmaFactorBS="ctcaagatttaccacacaattctcCGCATGAttttccggcca tttTAACATAATACGtagtaacaagccggcaaagcattgggttacgccgaggcggcag t" /listShort="S342, sspB" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(1050443..1050661) /gene="yheE" /locus_tag="BSU_09760" /old_locus_tag="BSU09760" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein (sporulation / germination island)" /protein_id="NP_388857.1" /db_xref="EnsemblGenomes-Gn:BSU09760" /db_xref="EnsemblGenomes-Tr:CAB12815" /db_xref="InterPro:IPR017263" /db_xref="SubtiList:BG13037" /db_xref="UniProtKB/Swiss-Prot:O07546" /translation="MAVMISHFSWKPLFPKEKLPGWKISFYYKGTHYEGIYHKSGEIE WGDLFPARADEPALTNEIHELMLFHIYD*" gene complement(1050443..1050661) /gene="yheE" /locus_tag="BSU_09760" /old_locus_tag="BSU09760" downshifts complement(1050477) /Source="Nicolas_upshifts" /id="D519" /incds=0 /nref=5 /ntot=83 /MaxReadThrough="0.43384" /MaxDrop="3.42951" /score="37.4339943" /energy="-11.8" /TU="NA" /idTUdmin="U777" /TUdmin=110 /isTUend="FALSE" promotor_-10 complement(1050702..1050721) /Source="Nicolas_upshift_promotors" /id="U777" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.609390609390609" /psig="0.996003996003996" /xcortree=419 /SigmaFactorBS="ctttatccaaagctgggacaaactgcatatttaggccTCTTC AATgatgttctgaaacAATGATACAATGAACATAAGccgtttttatttaggtcaattg a" /listShort="yheE" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1050719) /Source="Nicolas_upshifts" /id="U777" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.609390609390609" /psig="0.996003996003996" /xcortree=419 /SigmaFactorBS="ctttatccaaagctgggacaaactgcatatttaggccTCTTC AATgatgttctgaaacAATGATACAATGAACATAAGccgtttttatttaggtcaattg a" /listShort="yheE" /GFF_Attribute="listLong" promotor_-35 complement(1050735..1050742) /Source="Nicolas_upshift_promotors" /id="U777" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.609390609390609" /psig="0.996003996003996" /xcortree=419 /SigmaFactorBS="ctttatccaaagctgggacaaactgcatatttaggccTCTTC AATgatgttctgaaacAATGATACAATGAACATAAGccgtttttatttaggtcaattg a" /listShort="yheE" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(1050811..1052172) /gene="spaD" /locus_tag="BSU_09770" /old_locus_tag="BSU09770" /function="16.5: Explore" /function="16.8: Protect" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:15231775, 25035995" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15231775, 25035995; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="spore coat associated protein" /protein_id="NP_388858.2" /db_xref="EnsemblGenomes-Gn:BSU09770" /db_xref="EnsemblGenomes-Tr:CAB12816" /db_xref="GOA:O07545" /db_xref="InterPro:IPR013815" /db_xref="InterPro:IPR026838" /db_xref="SubtiList:BG13036" /db_xref="UniProtKB/Swiss-Prot:O07545" /translation="MNPKRFLIGIDKTSENTLFLPSSLKQDGLLHAAFGTKVVRCHVA YRRHLEQTVLLSENLFHELLLPHRSRADILIHDHTVHIGPLVGIFTAGFTVSLERPFK DRSLFFSKLVTLHEQAGGYCFVFGAHQINWEEGTIEGLLYRENGWEKKIVPLPNVVYD RLPNRKIEDSLLLQHTKKRLIDEYQIPWFNKTFFNKWNVHQLLEKDPRTAPFLPRSEL TPSVELIDELCGAYKKVYIKPANGALGTGIYQLTRTDGGLTVKHTNDAKTFTSIDYSD AASFLAEFQKHHNPSDFLIQQGVDLIEFQGKPADFRVHTNKNRKGKWTVTAIAVKISG KNSITTHLSNGGTVKTLAEVYDDPAERVEVIKKLSAAALTASHVLHDHIEGFIGEIGF DFGIDQNGKVWMFEANSRPGRSIFSHPNLHHVDSLTKRRSFEYASYLSEKAITSPEAL WPS*" gene complement(1050811..1052172) /gene="spaD" /locus_tag="BSU_09770" /old_locus_tag="BSU09770" downshifts complement(1050829) /Source="Nicolas_upshifts" /id="D520" /incds=0 /nref=3 /ntot=26 /MaxReadThrough="2.33323" /MaxDrop="3.7968" /score="37.4339943" /energy="-11.8" /TU="NA" /idTUdmin="U779" /TUdmin=0 /isTUend="TRUE" downshifts complement(1050873) /Source="Nicolas_upshifts" /id="D521" /incds=1 /nref=2 /ntot=45 /MaxReadThrough="5.29177" /MaxDrop="3.36501" /score="37.4339943" /energy="-11.8" /TU="U779" /idTUdmin="U779" /TUdmin="-44" /isTUend="FALSE" CDS complement(1052162..1053253) /gene="spaC" /locus_tag="BSU_09780" /old_locus_tag="BSU09780" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2b: Function from indirect experimental evidences (e.g. phenotypes); PubMedId: 15231775, 25035995; Product type f: factor" /codon_start=1 /transl_table=11 /product="spore coat associated protein, subunit C" /protein_id="NP_388859.1" /db_xref="EnsemblGenomes-Gn:BSU09780" /db_xref="EnsemblGenomes-Tr:CAB12817" /db_xref="GOA:O07544" /db_xref="InterPro:IPR013815" /db_xref="InterPro:IPR026838" /db_xref="SubtiList:BG13035" /db_xref="UniProtKB/Swiss-Prot:O07544" /translation="MITLGFMSLSRQHEADYSAELAKRAPEFGIRFIRFTPFDISPDT LRVKASVYHSASSTWNETEMAIPDYIYDRCFYGKDSHSQKAKPIVEWLKKYPKTEFIG RGLPDKWTVLHDLQQHSVINPYIPETIKVSRYEQIHSFLSKEKACILKPAFGAGGRGV ILLKLGKKNITATYHIGKDKQTKTFSNQTSFKTWCKKVLQHQYLLQPYLNIQDKEQYP CDIRLFMEKNEAGEWNTVGKAVRRGYKHGLLANLSGGSDALTFDSWFEDIPKKQQVVL LDDVFSITQSVPYYLDERYGPLFELGLDICLAKDGRIWILDINSKPGRKSILRVSPEQ KEQLYTCPLKRCQYLFSEQSQKGVLPRES*" gene complement(1052162..1053253) /gene="spaC" /locus_tag="BSU_09780" /old_locus_tag="BSU09780" promotor_-10 complement(1052577..1052591) /Source="Nicolas_upshift_promotors" /id="U778" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp="0.63936063936064" /psig="0.63936063936064" /xcortree=613 /SigmaFactorBS="aatatttgcttcagccttacttaaacattcaagataAGGAAC AATacccttgtgatatTCGTCTGTTTATGGAaaaaaacgaagcaggtgaatggaatac a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1052589) /Source="Nicolas_upshifts" /id="U778" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp="0.63936063936064" /psig="0.63936063936064" /xcortree=613 /SigmaFactorBS="aatatttgcttcagccttacttaaacattcaagataAGGAAC AATacccttgtgatatTCGTCTGTTTATGGAaaaaaacgaagcaggtgaatggaatac a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(1052605..1052613) /Source="Nicolas_upshift_promotors" /id="U778" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp="0.63936063936064" /psig="0.63936063936064" /xcortree=613 /SigmaFactorBS="aatatttgcttcagccttacttaaacattcaagataAGGAAC AATacccttgtgatatTCGTCTGTTTATGGAaaaaaacgaagcaggtgaatggaatac a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" S_feature complement(1053254..1053359) /Source="Nicolas_S_feature" /locus_tag="new_1053254_1053359_c" /HighExp="S4, B36, S5, S6, S7, S8, B60, S3, T5.0H, BT" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigEF" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S343" promotor_-10 complement(1053343..1053361) /Source="Nicolas_upshift_promotors" /id="U779" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1099 /SigmaFactorBS="ggagacaaattcctgttcttagaaaatcagcttgttcttttG GAATAgggcaaggtggagaaTCGTATTCTGTAAAGTAGAataccgtcagctgcgttcg t" /listShort="S343, yheC, yheD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1053363) /Source="Nicolas_upshifts" /id="U779" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1099 /SigmaFactorBS="ggagacaaattcctgttcttagaaaatcagcttgttcttttG GAATAgggcaaggtggagaaTCGTATTCTGTAAAGTAGAataccgtcagctgcgttcg t" /listShort="S343, yheC, yheD" /GFF_Attribute="listLong" promotor_-35 complement(1053377..1053382) /Source="Nicolas_upshift_promotors" /id="U779" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1099 /SigmaFactorBS="ggagacaaattcctgttcttagaaaatcagcttgttcttttG GAATAgggcaaggtggagaaTCGTATTCTGTAAAGTAGAataccgtcagctgcgttcg t" /listShort="S343, yheC, yheD" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1053425..1053432 /Source="Nicolas_upshift_promotors" /id="U780" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.983016983016983" /psig=1 /xcortree=2000 /SigmaFactorBS="ttttctaagaacaggaatttgtctcctCGTTTGCTaagtgat tgcatgaGCCTCTATAATACGTATAGGtacataatctatatgaaaaaagctgaagcac a" /listShort="yheB, S344, yheA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1053447..1053466 /Source="Nicolas_upshift_promotors" /id="U780" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.983016983016983" /psig=1 /xcortree=2000 /SigmaFactorBS="ttttctaagaacaggaatttgtctcctCGTTTGCTaagtgat tgcatgaGCCTCTATAATACGTATAGGtacataatctatatgaaaaaagctgaagcac a" /listShort="yheB, S344, yheA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1053458 /Source="Nicolas_upshifts" /id="U780" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.983016983016983" /psig=1 /xcortree=2000 /SigmaFactorBS="ttttctaagaacaggaatttgtctcctCGTTTGCTaagtgat tgcatgaGCCTCTATAATACGTATAGGtacataatctatatgaaaaaagctgaagcac a" /listShort="yheB, S344, yheA" /GFF_Attribute="listLong" CDS 1053520..1054653 /gene="yheB" /locus_tag="BSU_09790" /old_locus_tag="BSU09790" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 16684363" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_388860.1" /db_xref="EnsemblGenomes-Gn:BSU09790" /db_xref="EnsemblGenomes-Tr:CAB12818" /db_xref="GOA:O07543" /db_xref="InterPro:IPR007383" /db_xref="InterPro:IPR016991" /db_xref="SubtiList:BG13034" /db_xref="UniProtKB/Swiss-Prot:O07543" /translation="MGIAGTFIFMIVIGAAIGAVTNHLAIQMLFRPYKAYYLFGKRVP FTPGLIPRRRDELAKQMGLMVVNHLLTPEGIKKRLVSDAAKTQALRVGEQLIQKLSLS EVTVKEALEKAGMKRPEKAADAWISSWTDDKLHELFRQYGDQSLKELVPIEVQEKLEE KIPMISGYILSRSVRYFESDEGKIRLGNMIDDFLKERGMLGSMVQLFLGNSSLADRVL PELLKFLRNEETNKLLSDLLKNEWGKLREYTFNEADEKWNAKALIFSLKRRVLQAFST APFFNNTIGTLTVRYESELTQQMLPALLDKLLEGISSNLESVLKRLRLEEIVKEQVDQ FPVERLEEMVLSISKKEFKMITYLGGLLGGIIGAIQALFVILF*" gene 1053520..1054653 /gene="yheB" /locus_tag="BSU_09790" /old_locus_tag="BSU09790" S_feature 1054654..1054745 /Source="Nicolas_S_feature" /locus_tag="new_1054654_1054745" /HighExp="S4, S5, S6, BT, S3, S7, dia15, B36, G/S, LoTm" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S344" CDS 1054746..1055099 /gene="yheA" /locus_tag="BSU_09800" /old_locus_tag="BSU09800" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 19429628, 22720735" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_388861.1" /db_xref="EnsemblGenomes-Gn:BSU09800" /db_xref="EnsemblGenomes-Tr:CAB12819" /db_xref="InterPro:IPR010368" /db_xref="InterPro:IPR023378" /db_xref="PDB:2OEE" /db_xref="SubtiList:BG13033" /db_xref="UniProtKB/Swiss-Prot:O07542" /translation="MAVNFYDVAYDLENALRGSEEFTRLKNLYDEVNADESAKRMFEN FRDVQLRLQQKQMAGEEITQEEVTQAQKTVALVQQHEKISQLMEAEQRMSMLIGELNK IIMKPLEELYGSVEG*" gene 1054746..1055099 /gene="yheA" /locus_tag="BSU_09800" /old_locus_tag="BSU09800" downshifts 1055087 /Source="Nicolas_upshifts" /id="D522" /incds=0 /nref=159 /ntot=259 /MaxReadThrough="1.55668" /MaxDrop="5.9901" /score="24.5275597" /energy="-12.3" /TU="NA" /idTUdmin="U780" /TUdmin=0 /isTUend="TRUE" CDS complement(1055143..1056216) /gene="yhaZ" /locus_tag="BSU_09810" /old_locus_tag="BSU09810" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 16267290, 22933559" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_388862.1" /db_xref="EnsemblGenomes-Gn:BSU09810" /db_xref="EnsemblGenomes-Tr:CAB12820" /db_xref="GOA:O07541" /db_xref="InterPro:IPR011989" /db_xref="InterPro:IPR014825" /db_xref="InterPro:IPR016024" /db_xref="InterPro:IPR021133" /db_xref="SubtiList:BG13002" /db_xref="UniProtKB/Swiss-Prot:O07541" /translation="MADLKEIYNEELISQLIHHVRSSYPDFNKNRFLDTLRLEDWPEL TLKERMRRVTVSLYETLPKQYVEALTILRDTAPHFKGLSGILFPDYVEQYGLAHWEES IKALESFTQYSTSEFAVRPFLLLDQEKMIAQLLAWSEHKNEHVRRLASEGSRPRLPWG KSIPALKSDPSPVLPILEKLMQDESLYVRKSVANNLNDISKTHPHLLRKVADQWYGTH PHTDWIIKHAYRTLLKKGDKQALALFGYENADSIQLHDLTCQPKRIVIGESLEFSFYI HSDRDQKVRIEYAIDFVKARGQRHQKVFKITETNIRKNETKSYTRIQSFKDLTTRKHY KGIHTLSVIINGEVKDSLDFQVC*" gene complement(1055143..1056216) /gene="yhaZ" /locus_tag="BSU_09810" /old_locus_tag="BSU09810" downshifts complement(1055250) /Source="Nicolas_upshifts" /id="D523" /incds=1 /nref=16 /ntot=173 /MaxReadThrough="3.78071" /MaxDrop="3.586" /score="4.43596345" /energy="-12.3" /TU="U781" /idTUdmin="U781" /TUdmin="-109" /isTUend="FALSE" promotor_-10 complement(1056238..1056257) /Source="Nicolas_upshift_promotors" /id="U781" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.93006993006993" /psig=1 /xcortree=2090 /SigmaFactorBS="ggtaggatcagttgttaatttttaggactataCACTTGATcc agaacgtacatTCCCATACAATATAAATAATaaacgaaaaagcggtgtttatatggct g" /listShort="yhaZ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1056250) /Source="Nicolas_upshifts" /id="U781" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.93006993006993" /psig=1 /xcortree=2090 /SigmaFactorBS="ggtaggatcagttgttaatttttaggactataCACTTGATcc agaacgtacatTCCCATACAATATAAATAATaaacgaaaaagcggtgtttatatggct g" /listShort="yhaZ" /GFF_Attribute="listLong" promotor_-35 complement(1056271..1056278) /Source="Nicolas_upshift_promotors" /id="U781" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.93006993006993" /psig=1 /xcortree=2090 /SigmaFactorBS="ggtaggatcagttgttaatttttaggactataCACTTGATcc agaacgtacatTCCCATACAATATAAATAATaaacgaaaaagcggtgtttatatggct g" /listShort="yhaZ" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1056353..1056360 /Source="Nicolas_upshift_promotors" /id="U782" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.882117882117882" /psig=1 /xcortree=344 /SigmaFactorBS="ggatatacaaaagttggttactttttttagttaaaaaaacCC TTGTCAtcggaaaggaaaacTGAGATAATAACATTGAAAGcgcctacacttacctatt t" /listShort="S345, S346, yhaX" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 1056373 /Source="Nicolas_upshifts" /id="U782" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.882117882117882" /psig=1 /xcortree=344 /SigmaFactorBS="ggatatacaaaagttggttactttttttagttaaaaaaacCC TTGTCAtcggaaaggaaaacTGAGATAATAACATTGAAAGcgcctacacttacctatt t" /listShort="S345, S346, yhaX" /GFF_Attribute="listLong" promotor_-10 1056375..1056394 /Source="Nicolas_upshift_promotors" /id="U782" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.882117882117882" /psig=1 /xcortree=344 /SigmaFactorBS="ggatatacaaaagttggttactttttttagttaaaaaaacCC TTGTCAtcggaaaggaaaacTGAGATAATAACATTGAAAGcgcctacacttacctatt t" /listShort="S345, S346, yhaX" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 1056384..1056537 /Source="Nicolas_S_feature" /locus_tag="new_1056384_1056537" /HighExp="M9-stat, BC, T0.30H, T1.30H, Lbstat, T1.0H, T3.30H, T2.0H, T3.0H, M40t90" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S345" downshifts 1056494 /Source="Nicolas_upshifts" /id="D524" /incds=0 /nref=1 /ntot=37 /MaxReadThrough="7.40404" /MaxDrop="2.6506" /score="-6.05745557" /energy="-4.8" /TU="U782" /idTUdmin="U782" /TUdmin="-1056" /isTUend="FALSE" S_feature 1056539..1056622 /Source="Nicolas_S_feature" /locus_tag="new_1056539_1056622" /HighExp="M9-stat, B60, T2.0H, T1.30H, T0.30H, T2.30H, T3.0H, T1.0H, Lbtran, BC" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S346" downshifts 1056579 /Source="Nicolas_upshifts" /id="D525" /incds=0 /nref=70 /ntot=231 /MaxReadThrough="4.88371" /MaxDrop="4.4099" /score="-6.05745557" /energy="-4.8" /TU="U782" /idTUdmin="U782" /TUdmin="-971" /isTUend="FALSE" promotor_-35 1056635..1056640 /Source="Nicolas_upshift_promotors" /id="U783" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1164 /SigmaFactorBS="gccaggctttttttgctttaagaaaaggttGTTCTAaacaca gagacagggTCATATCCTATACACAAGTacagtcatcaaggagggggacatctctgtg t" /listShort="yhaX, hemZ" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1056656..1056674 /Source="Nicolas_upshift_promotors" /id="U783" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1164 /SigmaFactorBS="gccaggctttttttgctttaagaaaaggttGTTCTAaacaca gagacagggTCATATCCTATACACAAGTacagtcatcaaggagggggacatctctgtg t" /listShort="yhaX, hemZ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1056665 /Source="Nicolas_upshifts" /id="U783" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1164 /SigmaFactorBS="gccaggctttttttgctttaagaaaaggttGTTCTAaacaca gagacagggTCATATCCTATACACAAGTacagtcatcaaggagggggacatctctgtg t" /listShort="yhaX, hemZ" /GFF_Attribute="listLong" CDS 1056702..1057568 /gene="yhaX" /locus_tag="BSU_09830" /old_locus_tag="BSU09830" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 11988534; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative hydrolase" /protein_id="NP_388864.2" /db_xref="EnsemblGenomes-Gn:BSU09830" /db_xref="EnsemblGenomes-Tr:CAB12822" /db_xref="GOA:O07539" /db_xref="InterPro:IPR000150" /db_xref="InterPro:IPR006379" /db_xref="InterPro:IPR036412" /db_xref="PDB:3DNP" /db_xref="SubtiList:BG13000" /db_xref="UniProtKB/Swiss-Prot:O07539" /translation="MSKQLLALNIDGALLRSNGKIHQATKDAIEYVKKKGIYVTLVTN RHFRSAQKIAKSLKLDAKLITHSGAYIAEKIDAPFFEKRISDDHTFNIVQVLESYQCN IRLLHEKYSIGNKKKVNSNLLGKALIHPSDPIFYPVQFVESLSDLLMDEPVSAPVIEV YTEHDIQHDITETITKAFPAVDVIRVNDEKLNIVPKGVSKEAGLALVASELGLSMDDV VAIGHQYDDLPMIELAGLGVAMGNAVPEIKRKADWVTRSNDEQGVAYMMKEYFRMQQR KGFLDKFHMKRV*" gene 1056702..1057568 /gene="yhaX" /locus_tag="BSU_09830" /old_locus_tag="BSU09830" downshifts 1057550 /Source="Nicolas_upshifts" /id="D526" /incds=0 /nref=22 /ntot=67 /MaxReadThrough="3.99904" /MaxDrop="4.7771" /score="15.7706912" /energy="-16.6" /TU="U783" /idTUdmin="U782" /TUdmin=0 /isTUend="TRUE" promotor_-35 1057613..1057616 /Source="Nicolas_upshift_promotors" /id="U784" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.786213786213786" /psig=1 /xcortree=1455 /SigmaFactorBS="cgcgccctgacaggtgcggcggcttttttgccggATTGattt tagcagtttaTTTCTGTACACTAAAGAAAGttttgaatctgataaattaggtgatgaa g" /listShort="hemZ" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1057631..1057650 /Source="Nicolas_upshift_promotors" /id="U784" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.786213786213786" /psig=1 /xcortree=1455 /SigmaFactorBS="cgcgccctgacaggtgcggcggcttttttgccggATTGattt tagcagtttaTTTCTGTACACTAAAGAAAGttttgaatctgataaattaggtgatgaa g" /listShort="hemZ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1057639 /Source="Nicolas_upshifts" /id="U784" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.786213786213786" /psig=1 /xcortree=1455 /SigmaFactorBS="cgcgccctgacaggtgcggcggcttttttgccggATTGattt tagcagtttaTTTCTGTACACTAAAGAAAGttttgaatctgataaattaggtgatgaa g" /listShort="hemZ" /GFF_Attribute="listLong" CDS 1057680..1059185 /gene="hemZ" /locus_tag="BSU_09840" /old_locus_tag="BSU09840" /EC_number="1.3.99.-" /function="16.2: Construct biomass (Anabolism)" /function="16.10: Respire" /experiment="publication(s) with functional evidences, PMID:10498703, 21255303" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10498703, 21255303; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="coproporphyrinogen III oxidase" /protein_id="NP_388865.1" /db_xref="EnsemblGenomes-Gn:BSU09840" /db_xref="EnsemblGenomes-Tr:CAB12823" /db_xref="GOA:Q796V8" /db_xref="InterPro:IPR006638" /db_xref="InterPro:IPR007197" /db_xref="InterPro:IPR013785" /db_xref="InterPro:IPR023995" /db_xref="InterPro:IPR034505" /db_xref="SubtiList:BG12999" /db_xref="UniProtKB/Swiss-Prot:Q796V8" /translation="MQIKIEGIHDDRLHRPLQNIANLFYEECELAYGGEEPADFVISL ALSQTDEHVTVSGEVKGTGIKEQHTKFFSPDMTEKEAFKQVKNTISYVYLNLLQAHTG ITQKWGILTGIRPTKLLHKKLQSGMSKEQAHAELKKDYLIHDEKIMLMQEIVDRQLAA VPDLYRVKDEVSIYIGIPFCPTKCAYCTFPAYAIQGQAGRVGSFLWGLHYEMQKIGEW LKEHDVKVTTIYFGGGTPTSITAEEMDLLYEEMVRSFPDVKNIREITVEAGRPDTITE EKLAVLNKYDIDRISINPQSYENETLKAIGRHHTVEETIEKYHLSRQHGMNNINMDLI IGLPGEGVKEFRHSLSETEKLMPESLTVHTLSFKRASEMTRNKHKYKVAGREEVSQMM EDAVAWTKEHGYVPYYLYRQKNILGNLENVGYSLPGQESIYNIMIMEEVQTIIGIGCG AASKFIDRDTGKITHFANPKDPKSYNERFEHYTDEKIKYLEQIFEKTTKQH*" gene 1057680..1059185 /gene="hemZ" /locus_tag="BSU_09840" /old_locus_tag="BSU09840" downshifts 1059155 /Source="Nicolas_upshifts" /id="D527" /incds=0 /nref=113 /ntot=234 /MaxReadThrough="0.523269999999999" /MaxDrop="5.05369" /score="38.1573779" /energy="-14.4" /TU="NA" /idTUdmin="U783" /TUdmin="-1" /isTUend="TRUE" CDS complement(1059203..1060420) /gene="khtU" /locus_tag="BSU_09850" /old_locus_tag="BSU09850" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:7934942, 14987767, 15849754, 15919996, 16850406, 24330391" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7934942, 14987767, 15849754, 15919996, 16850406, 24330391; Product type t : transporter" /codon_start=1 /transl_table=11 /product="proton/potassium antiporter; methylglyoxal resistance" /protein_id="NP_388866.2" /db_xref="EnsemblGenomes-Gn:BSU09850" /db_xref="EnsemblGenomes-Tr:CAB12825" /db_xref="GOA:O07536" /db_xref="InterPro:IPR006153" /db_xref="SubtiList:BG12997" /db_xref="UniProtKB/Swiss-Prot:O07536" /translation="MDHLVFEVGTALVLVAIASVIANKIKFSIIPFLIVLGMLVGPHA PKMGIIDLTFIQSSEIIEFFGRMGVLFLLFYLGLEFSVGKLIKSGKSIAVGGTIYILI NFSLGLLYGFITGFSFLEVLILAGVITISSSAIVAKVLVDLKRTANPETELILGIIMF EDIFLAVYLSVVSGLILGDATSVGSALLSILIAFGYMLLFFIAARKLPPLLNKLLDIR SNEVFIIVIFAALFFIAGFSETIHVAEAIGALLLGLVFSETEHSDRIEHLVVPFRDFF GAMFFFSFGLSIDPFSLGEAVWLALGAVILTILGNFIAGMVAGRRAGLSHKASSNIGL TIVSRGEFSIIVANLGIAGGLSATLKPFAALYVLILAILGPLVTKESKRIYRLLNKVF KWKPEVQPAKKQG*" gene complement(1059203..1060420) /gene="khtU" /locus_tag="BSU_09850" /old_locus_tag="BSU09850" downshifts complement(1059209) /Source="Nicolas_upshifts" /id="D528" /incds=0 /nref=154 /ntot=249 /MaxReadThrough="1.74386" /MaxDrop="6.8685" /score="8.64654688" /energy="-14.4" /TU="NA" /idTUdmin="U785" /TUdmin=1 /isTUend="TRUE" CDS complement(1060427..1060924) /gene="khtT" /locus_tag="BSU_09860" /old_locus_tag="BSU09860" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:14987767, 17679694" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 14987767, 17679694; Product type t: transporter" /codon_start=1 /transl_table=11 /product="K+/H+ antiporter for K+ efflux" /protein_id="NP_388867.1" /db_xref="EnsemblGenomes-Gn:BSU09860" /db_xref="EnsemblGenomes-Tr:CAB12826" /db_xref="GOA:O07535" /db_xref="InterPro:IPR006037" /db_xref="InterPro:IPR026278" /db_xref="InterPro:IPR036721" /db_xref="SubtiList:BG12996" /db_xref="UniProtKB/Swiss-Prot:O07535" /translation="MNIKENDLPGIGKKFEIETRSHEKMTIIIHDDGRREIYRFNDRD PDELLSNISLDDSEARQIAAILGGMVYKPQALESIEMAFSDLIIEWFKVEKGAKSIGR TLGELDVRQNYDVTVIAIIKHNQEKLLNPGADSIIEENDTLVLSGERKHLKKLIHDFL SGEGV*" gene complement(1060427..1060924) /gene="khtT" /locus_tag="BSU_09860" /old_locus_tag="BSU09860" CDS complement(1060988..1061326) /gene="khtS" /locus_tag="BSU_09870" /old_locus_tag="BSU09870" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:14987767, 17679694" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 14987767, 17679694; Product type t: transporter" /codon_start=1 /transl_table=11 /product="K+/H+ antiporter for K+ efflux" /protein_id="NP_388868.1" /db_xref="EnsemblGenomes-Gn:BSU09870" /db_xref="EnsemblGenomes-Tr:CAB12827" /db_xref="GOA:O07534" /db_xref="SubtiList:BG12995" /db_xref="UniProtKB/Swiss-Prot:O07534" /translation="MRREERNMDKLLISFLLSLFMVYFPPSDVVLPSQFEASTDSYVP MSSYPQETQSAKTPSPGSMHPAELIKEYSPLAQSVRQLSVKPLDEPLINRLEKALAVP VKYQSNYLRI*" gene complement(1060988..1061326) /gene="khtS" /locus_tag="BSU_09870" /old_locus_tag="BSU09870" promotor_-10 complement(1061338..1061357) /Source="Nicolas_upshift_promotors" /id="U785" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.95004995004995" /psig="0.97902097902098" /xcortree=628 /SigmaFactorBS="acctttttatttttcaaggtcaatagatactgaaaaatgcat atTGTTTGAAtggaaacataaagTTTTATATAGTGAAAAAGAAgggatatcttgatga g" /listShort="khtS, khtT, yhaU" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1061362) /Source="Nicolas_upshifts" /id="U785" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.95004995004995" /psig="0.97902097902098" /xcortree=628 /SigmaFactorBS="acctttttatttttcaaggtcaatagatactgaaaaatgcat atTGTTTGAAtggaaacataaagTTTTATATAGTGAAAAAGAAgggatatcttgatga g" /listShort="khtS, khtT, yhaU" /GFF_Attribute="listLong" promotor_-35 complement(1061371..1061378) /Source="Nicolas_upshift_promotors" /id="U785" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.95004995004995" /psig="0.97902097902098" /xcortree=628 /SigmaFactorBS="acctttttatttttcaaggtcaatagatactgaaaaatgcat atTGTTTGAAtggaaacataaagTTTTATATAGTGAAAAAGAAgggatatcttgatga g" /listShort="khtS, khtT, yhaU" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1061398..1061405 /Source="Nicolas_upshift_promotors" /id="U786" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.825174825174825" /psig="0.971028971028971" /xcortree=364 /SigmaFactorBS="attcaaacaatatgcatttttcagtatcTATTGACCttgaaa aataaaaaGGTTTATTTGGGGATGGCGGggaatgtataggagaaagaaaaaagtaagc g" /listShort="yhaR" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1061420..1061439 /Source="Nicolas_upshift_promotors" /id="U786" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.825174825174825" /psig="0.971028971028971" /xcortree=364 /SigmaFactorBS="attcaaacaatatgcatttttcagtatcTATTGACCttgaaa aataaaaaGGTTTATTTGGGGATGGCGGggaatgtataggagaaagaaaaaagtaagc g" /listShort="yhaR" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1061430 /Source="Nicolas_upshifts" /id="U786" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.825174825174825" /psig="0.971028971028971" /xcortree=364 /SigmaFactorBS="attcaaacaatatgcatttttcagtatcTATTGACCttgaaa aataaaaaGGTTTATTTGGGGATGGCGGggaatgtataggagaaagaaaaaagtaagc g" /listShort="yhaR" /GFF_Attribute="listLong" CDS 1061491..1062258 /gene="yhaR" /locus_tag="BSU_09880" /old_locus_tag="BSU09880" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 22961985; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative dehydratase / isomerase" /protein_id="NP_388869.3" /db_xref="EnsemblGenomes-Gn:BSU09880" /db_xref="EnsemblGenomes-Tr:CAB12828" /db_xref="GOA:O07533" /db_xref="InterPro:IPR001753" /db_xref="InterPro:IPR014748" /db_xref="InterPro:IPR029045" /db_xref="SubtiList:BG12994" /db_xref="UniProtKB/Swiss-Prot:O07533" /translation="MEFVQYACNGAVAEIILNRPDAHHALNEQMLSELKEAVEMAAAS EALIVLLRGSGKGFSAGGDIRMMTSEHDPDQFKRLMDTIEAVTLNLYQMKKVTIAAIH GAAAGLGLSLALCADIVLAEKNAVLAMNFIGIGLVPDGGGHYLLKKRIGEAKAKKLIW SGKKLSASEAADMGLLDGTFAGDPAEGARPIIETLLASPLLAMIETKGIFQSLQIEEL KKVLSLERSAQERMRRTKDHQEGIRAFLEKREPKFQA*" gene 1061491..1062258 /gene="yhaR" /locus_tag="BSU_09880" /old_locus_tag="BSU09880" downshifts 1062259 /Source="Nicolas_upshifts" /id="D529" /incds=0 /nref=2 /ntot=99 /MaxReadThrough="1.78111" /MaxDrop="4.66019" /score="-8.79921781" /energy="-7.5" /TU="NA" /idTUdmin="U786" /TUdmin=0 /isTUend="TRUE" CDS complement(1062279..1062464) /gene="yhzD" /locus_tag="BSU_09889" /old_locus_tag="BSU09889" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="YP_003097698.1" /db_xref="EnsemblGenomes-Gn:BSU09889" /db_xref="EnsemblGenomes-Tr:CAX52586" /db_xref="InterPro:IPR025544" /db_xref="UniProtKB/Swiss-Prot:C0H3Y1" /translation="MADYFLTVFDPSGNTLVNEQFEAEHEEAAKTHGEALLKEKELHS HTHRLVNAAGKLILFHR*" gene complement(1062279..1062464) /gene="yhzD" /locus_tag="BSU_09889" /old_locus_tag="BSU09889" promotor_-10 complement(1062500..1062518) /Source="Nicolas_upshift_promotors" /id="U787" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.637362637362637" /psig="0.637362637362637" /xcortree=957 /SigmaFactorBS="acccattatatactaattttggataaagcataatAAAGGATT TtgatttccttTTTAGAATATAAATGAAGAaagactgataaaccttaaaatggaggag a" /listShort="yhzD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1062511) /Source="Nicolas_upshifts" /id="U787" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.637362637362637" /psig="0.637362637362637" /xcortree=957 /SigmaFactorBS="acccattatatactaattttggataaagcataatAAAGGATT TtgatttccttTTTAGAATATAAATGAAGAaagactgataaaccttaaaatggaggag a" /listShort="yhzD" /GFF_Attribute="listLong" promotor_-35 complement(1062529..1062537) /Source="Nicolas_upshift_promotors" /id="U787" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.637362637362637" /psig="0.637362637362637" /xcortree=957 /SigmaFactorBS="acccattatatactaattttggataaagcataatAAAGGATT TtgatttccttTTTAGAATATAAATGAAGAaagactgataaaccttaaaatggaggag a" /listShort="yhzD" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1062538..1062541 /Source="Nicolas_upshift_promotors" /id="U788" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.797202797202797" /psig="0.974025974025974" /xcortree=2418 /SigmaFactorBS="tttatattctaaaaaggaaatcaaaatcctttATTAtgcttt atccaaaaTTAGTATATAATGGGTCAGGgaaggaggagattcagtgcttacaattgat c" /listShort="natA, natB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1062556..1062575 /Source="Nicolas_upshift_promotors" /id="U788" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.797202797202797" /psig="0.974025974025974" /xcortree=2418 /SigmaFactorBS="tttatattctaaaaaggaaatcaaaatcctttATTAtgcttt atccaaaaTTAGTATATAATGGGTCAGGgaaggaggagattcagtgcttacaattgat c" /listShort="natA, natB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1062566 /Source="Nicolas_upshifts" /id="U788" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.797202797202797" /psig="0.974025974025974" /xcortree=2418 /SigmaFactorBS="tttatattctaaaaaggaaatcaaaatcctttATTAtgcttt atccaaaaTTAGTATATAATGGGTCAGGgaaggaggagattcagtgcttacaattgat c" /listShort="natA, natB" /GFF_Attribute="listLong" CDS 1062591..1063487 /gene="yhaQ" /locus_tag="BSU_09890" /old_locus_tag="BSU09890" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 9106203, 10356997, 12374817; Product type t: transporter" /codon_start=1 /transl_table=11 /product="Na+-dependent efflux ABC transporter (ATP-binding protein)" /protein_id="NP_388870.2" /db_xref="EnsemblGenomes-Gn:BSU09890" /db_xref="EnsemblGenomes-Tr:CAB12829" /db_xref="GOA:C0SPB4" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR017871" /db_xref="InterPro:IPR025302" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG12993" /db_xref="UniProtKB/Swiss-Prot:C0SPB4" /translation="MLTIDHVTKTFGDYKAVDGLDLDIPEQQMFGLLGANGAGKTTTF RMILGLLSITEGSISWKGRPVNYHISNKIGYLPEERGLYPKMKVRDQLVYLARLKGME KREAVKELGTWLERFNITDYENKKVEELSKGNQQKIQFISAVLHKPELLILDEPFSGL DPVNVELLKEAVISLKNSGVSILFSSHRMEHVEELCENLCILQKGKPVVQGKLKEIKR SFGKKNVTIHSDDDLRFLQSHEGILQWKETADGVKLQIANEDISQEIFAMLQGKGFIR KFELEEPSLHDIFIEKVGAVYE*" gene 1062591..1063487 /gene="yhaQ" /locus_tag="BSU_09890" /old_locus_tag="BSU09890" CDS 1063480..1064739 /gene="yhaP" /locus_tag="BSU_09900" /old_locus_tag="BSU09900" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 9106203, 10356997, 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="Na+-dependent exporter (ABC permease)" /protein_id="NP_388871.2" /db_xref="EnsemblGenomes-Gn:BSU09900" /db_xref="EnsemblGenomes-Tr:CAB12830" /db_xref="GOA:O07523" /db_xref="SubtiList:BG12992" /db_xref="UniProtKB/Swiss-Prot:O07523" /translation="MNKFWIMLSHTYKNKIMAKSFIISTVITVLLVLVVTNLESIISL FQGDDAKEKIAVVDETNELYPVFSKQLKAVDTDGDLDVKLSKQSEDEVTKQVKDESLD GMLIIKRDEKGTISGTYKALTISDESTYQTLQQALTQTKTAVGTAELGVSQETISSLY APVTVGQKALKEGAKSEEELGQTVGLVYIMLFVIYFSVIMYASMIAMEVATEKSSRVM EILISSMPPIQQMFAKLLGIGLVGITQLAIIIGAGSLSLKLNQKSETASSVGGFLNLT DVSATTVIYAVIFFLLGYFLYATLAAFLGSVVSRIEDVQQTITPMTLLVVAGFMIAMF GLNAPDAGFITVTSFIPFFTPMIMFLRVGMLDIPFWQAAVGIGITLLTIVILAVIGAR IYKGGVLIYGNSSAFKAIKQALRLAKN*" gene 1063480..1064739 /gene="yhaP" /locus_tag="BSU_09900" /old_locus_tag="BSU09900" downshifts 1064723 /Source="Nicolas_upshifts" /id="D530" /incds=0 /nref=19 /ntot=187 /MaxReadThrough="2.50232" /MaxDrop="3.26822" /score="8.93460501" /energy="-12.8" /TU="NA" /idTUdmin="U788" /TUdmin=0 /isTUend="TRUE" promotor_-35 1064787..1064794 /Source="Nicolas_upshift_promotors" /id="U789" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.682317682317682" /psig="0.998001998001998" /xcortree=2088 /SigmaFactorBS="cctggggattctcaggctgtttctttattgacagaaCGTGCA TTcgcaagaattcGGTGCTAAAATAAGGGTACTtcatcctggaaaggagcagaatgtt g" /listShort="yhaO, yhaN, yhaM" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1064806..1064825 /Source="Nicolas_upshift_promotors" /id="U789" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.682317682317682" /psig="0.998001998001998" /xcortree=2088 /SigmaFactorBS="cctggggattctcaggctgtttctttattgacagaaCGTGCA TTcgcaagaattcGGTGCTAAAATAAGGGTACTtcatcctggaaaggagcagaatgtt g" /listShort="yhaO, yhaN, yhaM" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1064811 /Source="Nicolas_upshifts" /id="U789" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.682317682317682" /psig="0.998001998001998" /xcortree=2088 /SigmaFactorBS="cctggggattctcaggctgtttctttattgacagaaCGTGCA TTcgcaagaattcGGTGCTAAAATAAGGGTACTtcatcctggaaaggagcagaatgtt g" /listShort="yhaO, yhaN, yhaM" /GFF_Attribute="listLong" CDS 1064846..1066072 /gene="yhaO" /locus_tag="BSU_09910" /old_locus_tag="BSU09910" /function="16.11: Scavenge (Catabolism)" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 16267290; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative DNA repair exonuclease" /protein_id="NP_388872.1" /db_xref="EnsemblGenomes-Gn:BSU09910" /db_xref="EnsemblGenomes-Tr:CAB12831" /db_xref="GOA:O07522" /db_xref="InterPro:IPR004843" /db_xref="InterPro:IPR014576" /db_xref="InterPro:IPR029052" /db_xref="SubtiList:BG12991" /db_xref="UniProtKB/Swiss-Prot:O07522" /translation="MLTDLTFIHAADLHLDSPFYGISHLPEPIFARIKESTFASVRHM IDAAVREHVDFILLAGDLFDEANRSLKAQLFLKKQFERLRECGISVYVIFGNHDHLGG EWTPIEWPENVHIFSSAVPEEKSFFKEGRRIASIYGFSYQARALMENQAARYRRSTDA PFHIGMLHGTLSGSEGHDPYCPFTHDDLVKSGMDYWALGHIHKRQVLSAEHPAVIYPG NTQARHIKETGDKGYYLVHVTNGDISYEFQRAHDVLWEKAAVDVTEAKNMTALFQMVE DTFSKLRKKGSPVCVRLVLQGTAPEWLLEAPKGTLDEFLEALQEQEAEEERFVWPLRL DDETENEANLTNLDPFFGGLFEDIDRSDLSDVLEGLERHPVYRRHADRFSQEEVKEIK EQAQIILKRQLKVLDT*" gene 1064846..1066072 /gene="yhaO" /locus_tag="BSU_09910" /old_locus_tag="BSU09910" downshifts complement(1065547) /Source="Nicolas_upshifts" /id="D531" /incds=1 /nref=1 /ntot=20 /MaxReadThrough="0.0165100000000002" /MaxDrop="3.62411" /score="-5.83060322" /energy="-15.2" /TU="NA" /idTUdmin="U787" /TUdmin="-3300" /isTUend="FALSE" CDS 1066077..1068968 /gene="sbcE" /locus_tag="BSU_09920" /old_locus_tag="BSU09920" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:16267290, 19906728, 21517913" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16267290, 19906728, 21517913; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="ATPase involved in DNA double strand break repair and recombination" /protein_id="NP_388873.1" /db_xref="EnsemblGenomes-Gn:BSU09920" /db_xref="EnsemblGenomes-Tr:CAB12832" /db_xref="GOA:O08455" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG12990" /db_xref="UniProtKB/Swiss-Prot:O08455" /translation="MTALRIISLHIYQYGKFSNRTFDFSASPVQVIYGLNEAGKTTMM SFIESMLFGFPKTKKYEPKTGGVYGGVLEAEHPEYGVLKIERTKGTAEKLSVYTEKGE VKQGDVLKQLFQGTDRSLYKAIYSFDVFGLQEIHAFNRDKIGEFLLFSSLFGAEAVSK LDSRLTKESERLYKPNGRNPQLNQELETLKQLAVKLKQAEAEEAGYHQLLEEKRTLEA RLAAAETELKETAGHIRMIEGAIERKPLLNEKATLEQVIAEFPEHAGQFPADGLHQLE KYESHLHPKSAQLEALRVKMAELDKQRQKLIPDKELLAKETLIQELSAAFHMYQSWGE QLAAIQAQLRQTSAQTAAGLEQLNKTDENELLNMNTSYDYEWQLQQAVQQYVQARDRK RQLDETFELARQELEDAEKAVRAASSAILENSQRKDKEAALRAYDETQGQHQEQAKLR EQLTFFERQQAKQKKTVIAAGMLFIVLFSLLQQWIPAISFGAALIVYWLVSGKSSSRN SRETRQPMTDISPAEAEMLREALWEDDRNKQHLLTQRAALQQKEAAYERVIQQFEQWE AEMAPSFTQVERFMNELGFKEDPSFLLDAYSLMKDVKKEVKKKHELTIEAGRLKKHRR TFEERVSMLLPVNQSQDISISDALHTLRKNIEREKEIEKQKKEIETDIHYTKEQMLEL EQEIQYFHAQIEQLFAAAAAKDRDAFFAIAAISRQLKDTENKLHHVNAQLQGGYPEEL ELADSNTLSELKDKQFVENERKERLTEEIEQLRSQIALLSVKQEQLEASGMVSDLKLQ TEMQKERVKETAKKWASIQMVKQVIRNKLERHKKIELPRLLETAGEFFRPLTDGNYQT IYFSETDDSIMVMHRDGTVYHAEELSQGTCEQLYTAIRFALAVTRQGESKLPFQLDDS FVHFDQERLKRVLHVLYDLSEGGRQILYFTCHEHVKDAFHSSQIIHLVS*" gene 1066077..1068968 /gene="sbcE" /locus_tag="BSU_09920" /old_locus_tag="BSU09920" promotor_-35 1067358..1067363 /Source="Nicolas_upshift_promotors" /id="U790" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.983016983016983" /psig="0.983016983016983" /xcortree=796 /SigmaFactorBS="tcgtccgcgattcttgaaaacagccaaagaaaaGATAAAgaa gcagctcttagaGCATATGATGAAACACAGGggcagcaccaagagcaagcgaagctca g" /listShort="yhaM" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1067379..1067397 /Source="Nicolas_upshift_promotors" /id="U790" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.983016983016983" /psig="0.983016983016983" /xcortree=796 /SigmaFactorBS="tcgtccgcgattcttgaaaacagccaaagaaaaGATAAAgaa gcagctcttagaGCATATGATGAAACACAGGggcagcaccaagagcaagcgaagctca g" /listShort="yhaM" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1067385 /Source="Nicolas_upshifts" /id="U790" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.983016983016983" /psig="0.983016983016983" /xcortree=796 /SigmaFactorBS="tcgtccgcgattcttgaaaacagccaaagaaaaGATAAAgaa gcagctcttagaGCATATGATGAAACACAGGggcagcaccaagagcaagcgaagctca g" /listShort="yhaM" /GFF_Attribute="listLong" promotor_-35 1068976..1068981 /Source="Nicolas_upshift_promotors" /id="U791" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.420579420579421" /psig="0.998001998001998" /xcortree=2174 /SigmaFactorBS="atccatttggtgtcataaaagaggtTCTATAgctgaaaatcg gtaTGTGATATACTGGTATTATGtaagatacggagggagctttaatagaatggctaaa g" /listShort="yhaM" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1068996..1069015 /Source="Nicolas_upshift_promotors" /id="U791" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.420579420579421" /psig="0.998001998001998" /xcortree=2174 /SigmaFactorBS="atccatttggtgtcataaaagaggtTCTATAgctgaaaatcg gtaTGTGATATACTGGTATTATGtaagatacggagggagctttaatagaatggctaaa g" /listShort="yhaM" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1069011 /Source="Nicolas_upshifts" /id="U791" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.420579420579421" /psig="0.998001998001998" /xcortree=2174 /SigmaFactorBS="atccatttggtgtcataaaagaggtTCTATAgctgaaaatcg gtaTGTGATATACTGGTATTATGtaagatacggagggagctttaatagaatggctaaa g" /listShort="yhaM" /GFF_Attribute="listLong" CDS 1069042..1069986 /gene="yhaM" /locus_tag="BSU_09930" /old_locus_tag="BSU09930" /EC_number="3.1.-.-" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:12399495, 15805522, 15983136, 16267290, 19553197, 19880604" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12399495, 15805522, 15983136, 16267290, 19553197, 19880604; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="3'-5' exonuclease" /protein_id="NP_388874.1" /db_xref="EnsemblGenomes-Gn:BSU09930" /db_xref="EnsemblGenomes-Tr:CAB12833" /db_xref="GOA:O07521" /db_xref="InterPro:IPR003607" /db_xref="InterPro:IPR006674" /db_xref="InterPro:IPR012340" /db_xref="InterPro:IPR020873" /db_xref="SubtiList:BG12989" /db_xref="UniProtKB/Swiss-Prot:O07521" /translation="MAKGIMLHEVGEQVDQYLLIKSSTKGIASNGKPFLTLMLQDQSG DIEAKLWDAKQSDEVTYAPQTIVKVVGDVHHYRGRTQLKLRNIRPVSEQENVNIDDFL ETAPIPKNEMMDTITQYIFEMKNPNIQRITRFLVKKHEAEFMDYPAATKNHHEFVSGL AYHVVSMLNLAKAIADLYPSLDRDLLYAGVILHDLGKVKELSGPVSTSYTVEGNLLGH ISIMVTELSKAAEELQIDSEEVLILQHLILSHHGKAEWGSPKPPMVKEAEILHYIDNL DAKMNMMDRALERVKPGEYTERVFALENRSFYKPTFHK*" gene 1069042..1069986 /gene="yhaM" /locus_tag="BSU_09930" /old_locus_tag="BSU09930" downshifts 1069964 /Source="Nicolas_upshifts" /id="D532" /incds=0 /nref=183 /ntot=261 /MaxReadThrough="3.02818" /MaxDrop="5.88173" /score="6.06919899" /energy="-15.8" /TU="NA" /idTUdmin="U789" /TUdmin=5 /isTUend="TRUE" promotor_-35 1070045..1070050 /Source="Nicolas_upshift_promotors" /id="U792" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1159 /SigmaFactorBS="atattcagctcagtcctttttgatgcgtctttcccgCACATA actcgtctcattcccGCATATGGTTAAGAATAAAgaatctatgcaaagggggaggagc c" /listShort="yhaL" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1070066..1070084 /Source="Nicolas_upshift_promotors" /id="U792" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1159 /SigmaFactorBS="atattcagctcagtcctttttgatgcgtctttcccgCACATA actcgtctcattcccGCATATGGTTAAGAATAAAgaatctatgcaaagggggaggagc c" /listShort="yhaL" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1070069 /Source="Nicolas_upshifts" /id="U792" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1159 /SigmaFactorBS="atattcagctcagtcctttttgatgcgtctttcccgCACATA actcgtctcattcccGCATATGGTTAAGAATAAAgaatctatgcaaagggggaggagc c" /listShort="yhaL" /GFF_Attribute="listLong" CDS 1070111..1070323 /gene="yhaL" /locus_tag="BSU_09940" /old_locus_tag="BSU09940" /function="16.8: Protect" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:14523133" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 14523133; Product type ph: phenotype" /codon_start=1 /transl_table=11 /product="sporulation factor" /protein_id="NP_388875.1" /db_xref="EnsemblGenomes-Gn:BSU09940" /db_xref="EnsemblGenomes-Tr:CAB12834" /db_xref="GOA:O07520" /db_xref="InterPro:IPR025428" /db_xref="SubtiList:BG12988" /db_xref="UniProtKB/Swiss-Prot:O07520" /translation="MLFFPWWVYLCIVGIIFSAYKLVAAAKEEEKVDQAFIEKEGQIY MERMEKERERRSSQQHEEENQNHSIA*" gene 1070111..1070323 /gene="yhaL" /locus_tag="BSU_09940" /old_locus_tag="BSU09940" downshifts 1070316 /Source="Nicolas_upshifts" /id="D533" /incds=0 /nref=8 /ntot=158 /MaxReadThrough="2.03283" /MaxDrop="6.60832" /score="62.1892984" /energy="-22" /TU="NA" /idTUdmin="U792" /TUdmin=5 /isTUend="TRUE" downshifts complement(1070354) /Source="Nicolas_upshifts" /id="D534" /incds=0 /nref=97 /ntot=260 /MaxReadThrough="0.90997" /MaxDrop="9.00938" /score="52.3375501" /energy="-22" /TU="NA" /idTUdmin="U793" /TUdmin=11 /isTUend="TRUE" CDS complement(1070364..1071242) /gene="prsA" /locus_tag="BSU_09950" /old_locus_tag="BSU09950" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:12634326, 12682299, 14976191, 16516208, 25525259, 26711778" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12634326, 12682299, 14976191, 16516208, 25525259, 26711778; Product type lp : lipoprotein" /codon_start=1 /transl_table=11 /product="molecular chaperone lipoprotein" /protein_id="NP_388876.1" /db_xref="EnsemblGenomes-Gn:BSU09950" /db_xref="EnsemblGenomes-Tr:CAB12835" /db_xref="GOA:P24327" /db_xref="InterPro:IPR000297" /db_xref="InterPro:IPR008880" /db_xref="InterPro:IPR023058" /db_xref="InterPro:IPR023059" /db_xref="InterPro:IPR027304" /db_xref="PDB:1ZK6" /db_xref="PDB:4WO7" /db_xref="SubtiList:BG10464" /db_xref="UniProtKB/Swiss-Prot:P24327" /translation="MKKIAIAAITATSILALSACSSGDKEVIAKTDAGDVTKGELYTN MKKTAGASVLTQLVQEKVLDKKYKVSDKEIDNKLKEYKTQLGDQYTALEKQYGKDYLK EQVKYELLTQKAAKDNIKVTDADIKEYWEGLKGKIRASHILVADKKTAEEVEKKLKKG EKFEDLAKEYSTDSSASKGGDLGWFAKEGQMDETFSKAAFKLKTGEVSDPVKTQYGYH IIKKTEERGKYDDMKKELKSEVLEQKLNDNAAVQEAVQKVMKKADIEVKDKDLKDTFN TSSTSNSTSSSSSNSK*" gene complement(1070364..1071242) /gene="prsA" /locus_tag="BSU_09950" /old_locus_tag="BSU09950" downshifts complement(1070552) /Source="Nicolas_upshifts" /id="D535" /incds=1 /nref=10 /ntot=127 /MaxReadThrough="7.54458" /MaxDrop="3.5906" /score="52.3375501" /energy="-22" /TU="U793" /idTUdmin="U793" /TUdmin="-187" /isTUend="FALSE" promotor_-10 complement(1071280..1071299) /Source="Nicolas_upshift_promotors" /id="U793" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.565434565434565" /psig="0.996003996003996" /xcortree=1995 /SigmaFactorBS="gtcatcagcaaaagtttgactagacgaatgccctttatttaa aaTCTTTTTAcagaaagccacaaTATGTTATGATACGCATAGGtaatttaatttggaa t" /listShort="prsA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1071304) /Source="Nicolas_upshifts" /id="U793" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.565434565434565" /psig="0.996003996003996" /xcortree=1995 /SigmaFactorBS="gtcatcagcaaaagtttgactagacgaatgccctttatttaa aaTCTTTTTAcagaaagccacaaTATGTTATGATACGCATAGGtaatttaatttggaa t" /listShort="prsA" /GFF_Attribute="listLong" promotor_-35 complement(1071313..1071320) /Source="Nicolas_upshift_promotors" /id="U793" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.565434565434565" /psig="0.996003996003996" /xcortree=1995 /SigmaFactorBS="gtcatcagcaaaagtttgactagacgaatgccctttatttaa aaTCTTTTTAcagaaagccacaaTATGTTATGATACGCATAGGtaatttaatttggaa t" /listShort="prsA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1071340..1071349 /Source="Nicolas_upshift_promotors" /id="U794" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.995004995004995" /psig="0.995004995004995" /xcortree=1349 /SigmaFactorBS="tgtggctttctgtaaaaagattttaaataaagggcattcGTC TAGTCAAacttttgctgatGACATACTTATATATTGATCaagaaaaggaggtatgtaa c" /listShort="yhzE, S347, S349" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 1071361 /Source="Nicolas_upshifts" /id="U794" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.995004995004995" /psig="0.995004995004995" /xcortree=1349 /SigmaFactorBS="tgtggctttctgtaaaaagattttaaataaagggcattcGTC TAGTCAAacttttgctgatGACATACTTATATATTGATCaagaaaaggaggtatgtaa c" /listShort="yhzE, S347, S349" /GFF_Attribute="listLong" promotor_-10 1071362..1071381 /Source="Nicolas_upshift_promotors" /id="U794" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.995004995004995" /psig="0.995004995004995" /xcortree=1349 /SigmaFactorBS="tgtggctttctgtaaaaagattttaaataaagggcattcGTC TAGTCAAacttttgctgatGACATACTTATATATTGATCaagaaaaggaggtatgtaa c" /listShort="yhzE, S347, S349" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-10 complement(1071398..1071412) /Source="Nicolas_upshift_promotors" /id="U795" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp=1 /psig=0 /xcortree=700 /SigmaFactorBS="taagcaaaatgaacagtactacgagcaacgcgaaTCCGTtag agtatCCTCCGCTCATGTTAcatacctccttttcttgatcaatatataagtatgtcat c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1071399) /Source="Nicolas_upshifts" /id="U795" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp=1 /psig=0 /xcortree=700 /SigmaFactorBS="taagcaaaatgaacagtactacgagcaacgcgaaTCCGTtag agtatCCTCCGCTCATGTTAcatacctccttttcttgatcaatatataagtatgtcat c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" CDS 1071402..1071488 /gene="sscA" /locus_tag="BSU_09958" /old_locus_tag="BSU09958" /function="15.7: Sporulation and germination" /experiment="publication(s) with functional evidences, PMID:20156992, 21670523" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 20156992, 21670523; Product type ph: phenotype" /codon_start=1 /transl_table=11 /product="spore assembly and germination protein" /protein_id="YP_003097699.1" /db_xref="EnsemblGenomes-Gn:BSU09958" /db_xref="EnsemblGenomes-Tr:CAX52587" /db_xref="GOA:C0H3Y2" /db_xref="InterPro:IPR010070" /db_xref="UniProtKB/Swiss-Prot:C0H3Y2" /translation="MSGGYSNGFALLVVLFILLIIVGAAYIY*" gene 1071402..1071488 /gene="sscA" /locus_tag="BSU_09958" /old_locus_tag="BSU09958" promotor_-35 complement(1071421..1071425) /Source="Nicolas_upshift_promotors" /id="U795" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp=1 /psig=0 /xcortree=700 /SigmaFactorBS="taagcaaaatgaacagtactacgagcaacgcgaaTCCGTtag agtatCCTCCGCTCATGTTAcatacctccttttcttgatcaatatataagtatgtcat c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" S_feature 1071489..1071740 /Source="Nicolas_S_feature" /locus_tag="new_1071489_1071740" /HighExp="S8, S7, S6, BT, G/S, B36, Pyr, S5, B60, Glucon" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba=1 /TUshortSig="SigK" /TUshortPSig="0.995" /TUlongSig="NA" /TUlongPSig="NA" /label="S347" CDS 1071613..1071699 /gene="sscB" /locus_tag="BSU_09959" /old_locus_tag="BSU09959" /function="15.7: Sporulation and germination" /experiment="publication(s) with functional evidences, PMID:21670523" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 21670523; Product type f: factor" /codon_start=1 /transl_table=11 /product="spore and germination protein" /protein_id="YP_009513948.1" /db_xref="EnsemblGenomes-Gn:BSU09959" /db_xref="EnsemblGenomes-Tr:CCQ48595" /db_xref="GOA:L8EBJ6" /db_xref="InterPro:IPR010070" /db_xref="UniProtKB/TrEMBL:L8EBJ6" /translation="MGEVFAGGFALLVVLFILLIIIGASWLY*" gene 1071613..1071699 /gene="sscB" /locus_tag="BSU_09959" /old_locus_tag="BSU09959" downshifts 1071697 /Source="Nicolas_upshifts" /id="D536" /incds=0 /nref=28 /ntot=50 /MaxReadThrough="4.67734" /MaxDrop="4.7906" /score="14.3797211" /energy="-17.6" /TU="U794" /idTUdmin="U794" /TUdmin="-506" /isTUend="FALSE" S_feature complement(1071709..1071971) /Source="Nicolas_S_feature" /locus_tag="new_1071709_1071971_c" /HighExp="LBGtran, LBGstat, LPhT, LBGexp, HPh, dia15, T0.30H, dia0, G180, Lbexp" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="0.999, 0.995" /TUlongSig="SigA" /TUlongPSig="0.989" /label="S348" S_feature 1071742..1072225 /Source="Nicolas_S_feature" /locus_tag="new_1071742_1072225" /HighExp="S8, S6, S7, BT, C30, S5, Pyr, Glucon, G/S, C90" /AntisenseName="yhaJ" /AntisenseCor="-0.22462434208606599" /AntisenseRegPval="-3.7" /CDS_PredictionProba="NA" /TUshortSig="SigK" /TUshortPSig="0.995" /TUlongSig="NA" /TUlongPSig="NA" /label="S349" downshifts complement(1071752) /Source="Nicolas_upshifts" /id="D537" /incds=0 /nref=153 /ntot=265 /MaxReadThrough="1.32339" /MaxDrop="6.55635" /score="34.7913848" /energy="-17.6" /TU="NA" /idTUdmin="U796" /TUdmin="-1" /isTUend="TRUE" promotor_-10 complement(1071964..1071983) /Source="Nicolas_upshift_promotors" /id="U796" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.58041958041958" /psig="0.999000999001" /xcortree=2759 /SigmaFactorBS="gtgctggtggcgatttttcaatttgcattCTATCTtttttaa taaataTTTGGTAATGTAATATGGGAcagttcagagagagggggaatctcccatcatt t" /listShort="S348" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1071971) /Source="Nicolas_upshifts" /id="U796" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.58041958041958" /psig="0.999000999001" /xcortree=2759 /SigmaFactorBS="gtgctggtggcgatttttcaatttgcattCTATCTtttttaa taaataTTTGGTAATGTAATATGGGAcagttcagagagagggggaatctcccatcatt t" /listShort="S348" /GFF_Attribute="listLong" S_feature complement(1071973..1072041) /Source="Nicolas_S_feature" /locus_tag="new_1071973_1072041_c" /HighExp="Paraq, G180, C30, LBGexp, Oxctl, G135, Lbexp, Heat, G150, BMM" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.29568499999999998" /TUshortSig="SigA" /TUshortPSig="0.995" /TUlongSig="SigA" /TUlongPSig="0.989" /label="S350" promotor_-35 complement(1071997..1072002) /Source="Nicolas_upshift_promotors" /id="U796" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.58041958041958" /psig="0.999000999001" /xcortree=2759 /SigmaFactorBS="gtgctggtggcgatttttcaatttgcattCTATCTtttttaa taaataTTTGGTAATGTAATATGGGAcagttcagagagagggggaatctcccatcatt t" /listShort="S348" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(1072042..1072560) /gene="yhaJ" /locus_tag="BSU_09965" /old_locus_tag="BSU09965" /function="16.5: Explore" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 16845009, 21670523, 25651892; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative membrane enzyme" /protein_id="NP_388878.2" /db_xref="EnsemblGenomes-Gn:BSU09965" /db_xref="EnsemblGenomes-Tr:CAB12837" /db_xref="GOA:O07518" /db_xref="InterPro:IPR021683" /db_xref="SubtiList:BG12986" /db_xref="UniProtKB/Swiss-Prot:O07518" /translation="MNCWKTINLMKDYGAVRIILTAVCFMILVFISTFLAFELLRPGT SLSDEYVSLFGGLLVVILFVHKVIHVLPIICKKRKIEKKFYILRMRTWKRIPKTTMLI SLVSPFLLITPVLFYAALAFPNHAHYFCMISGIHAGYCLPDFLLALKLIKAPKTAFID QEADGLDILVEK*" gene complement(1072042..1072560) /gene="yhaJ" /locus_tag="BSU_09965" /old_locus_tag="BSU09965" promotor_-35 1072347..1072355 /Source="Nicolas_upshift_promotors" /id="U797" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=540 /SigmaFactorBS="ctatttttctttttttgcagatgattgGCAGGACATggatga ctttaTGTACAAATAAAATAACGAcgagcaaaccgccgaataaagatacatattcatc g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1072367..1072385 /Source="Nicolas_upshift_promotors" /id="U797" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=540 /SigmaFactorBS="ctatttttctttttttgcagatgattgGCAGGACATggatga ctttaTGTACAAATAAAATAACGAcgagcaaaccgccgaataaagatacatattcatc g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1072380 /Source="Nicolas_upshifts" /id="U797" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=540 /SigmaFactorBS="ctatttttctttttttgcagatgattgGCAGGACATggatga ctttaTGTACAAATAAAATAACGAcgagcaaaccgccgaataaagatacatattcatc g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 complement(1072591..1072610) /Source="Nicolas_upshift_promotors" /id="U798" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.44955044955045" /psig="0.995004995004995" /xcortree=2615 /SigmaFactorBS="aaaaatacctgccggatgatattttttcttaaaaaagCATTG ATtttttctcttgggagGAGTAAATTATTTTGAGATTctattcaagatgtatggaagg a" /listShort="yhaJ, S350, S348" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1072609) /Source="Nicolas_upshifts" /id="U798" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.44955044955045" /psig="0.995004995004995" /xcortree=2615 /SigmaFactorBS="aaaaatacctgccggatgatattttttcttaaaaaagCATTG ATtttttctcttgggagGAGTAAATTATTTTGAGATTctattcaagatgtatggaagg a" /listShort="yhaJ, S350, S348" /GFF_Attribute="listLong" promotor_-35 complement(1072626..1072632) /Source="Nicolas_upshift_promotors" /id="U798" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.44955044955045" /psig="0.995004995004995" /xcortree=2615 /SigmaFactorBS="aaaaatacctgccggatgatattttttcttaaaaaagCATTG ATtttttctcttgggagGAGTAAATTATTTTGAGATTctattcaagatgtatggaagg a" /listShort="yhaJ, S350, S348" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1072709..1072712 /Source="Nicolas_upshift_promotors" /id="U799" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.671328671328671" /psig="0.999000999001" /xcortree=2221 /SigmaFactorBS="gaaacaagcaaacaaactgcgaaatatggggttagaaCTTTc ttctcagtgaattATCAGCTAAAATAAGATTAAagatagaaagaagtggtgtggatgg a" /listShort="yhaI, S352" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1072727..1072746 /Source="Nicolas_upshift_promotors" /id="U799" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.671328671328671" /psig="0.999000999001" /xcortree=2221 /SigmaFactorBS="gaaacaagcaaacaaactgcgaaatatggggttagaaCTTTc ttctcagtgaattATCAGCTAAAATAAGATTAAagatagaaagaagtggtgtggatgg a" /listShort="yhaI, S352" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1072732 /Source="Nicolas_upshifts" /id="U799" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.671328671328671" /psig="0.999000999001" /xcortree=2221 /SigmaFactorBS="gaaacaagcaaacaaactgcgaaatatggggttagaaCTTTc ttctcagtgaattATCAGCTAAAATAAGATTAAagatagaaagaagtggtgtggatgg a" /listShort="yhaI, S352" /GFF_Attribute="listLong" CDS 1072768..1073109 /gene="yhaI" /locus_tag="BSU_09980" /old_locus_tag="BSU09980" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_388879.1" /db_xref="EnsemblGenomes-Gn:BSU09980" /db_xref="EnsemblGenomes-Tr:CAB12838" /db_xref="InterPro:IPR015058" /db_xref="InterPro:IPR035945" /db_xref="PDB:1SED" /db_xref="SubtiList:BG12985" /db_xref="UniProtKB/Swiss-Prot:O07517" /translation="MDSMDHRIERLEYYIQLLVKTVDMDRYPFYALLIDKGLSKEEGE AVMRICDELSEELATQKAQGFVTFDKLLALFAGQLNEKLDVHETIFALYEQGLYQELM EVFIDIMKHFD*" gene 1072768..1073109 /gene="yhaI" /locus_tag="BSU_09980" /old_locus_tag="BSU09980" S_feature complement(1072963..1073105) /Source="Nicolas_S_feature" /locus_tag="new_1072963_1073105_c" /HighExp="BC, S1, Sw, S2, S3, S8, S5, S4, S6, S7" /AntisenseName="yhaI" /AntisenseCor="5.4889858269512502E-2" /AntisenseRegPval="-0.4" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.989" /TUlongSig="NA" /TUlongPSig="NA" /label="S351" downshifts complement(1073006) /Source="Nicolas_upshifts" /id="D538" /incds=1 /nref=39 /ntot=209 /MaxReadThrough="2.89899" /MaxDrop="4.77791" /score="-6.0983333" /energy="-12.3" /TU="U801" /idTUdmin="U801" /TUdmin="-374" /isTUend="FALSE" CDS complement(1073106..1073717) /gene="scoC" /locus_tag="BSU_09990" /old_locus_tag="BSU09990" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:14629015, 15126467, 16321961, 16923912, 19801406, 20382764, 23660663, 25966844, 26473603, 26728191, 22720735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 14629015, 15126467, 16321961, 16923912, 19801406, 20382764, 23660663, 25966844, 26473603, 26728191, 22720735; Product type r : regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator of extracellular protease production, sporulation and bacilysin production (MarR family)" /protein_id="NP_388880.1" /db_xref="EnsemblGenomes-Gn:BSU09990" /db_xref="EnsemblGenomes-Tr:CAB12839" /db_xref="GOA:P11065" /db_xref="InterPro:IPR000835" /db_xref="InterPro:IPR023187" /db_xref="InterPro:IPR023488" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="PDB:2FXA" /db_xref="SubtiList:BG10659" /db_xref="UniProtKB/Swiss-Prot:P11065" /translation="MNRVEPPYDVKEALVFTQKMAQLSKALWKSIEKDWQQWLKPYDL NINEHHILWIAYQLNGASISEIAKFGVMHVSTAFNFSKKLEERGYLRFSKRLNDKRNT YVQLTEEGTEVFWSLLEEFDPTRNAVFKGSQPLYHLFGKFPEVAEMMCMIRHIYGDDF MEIFETSLTNIDNDFESVNGKLKKKAKDSAADEPAEELEPVNS*" gene complement(1073106..1073717) /gene="scoC" /locus_tag="BSU_09990" /old_locus_tag="BSU09990" S_feature 1073110..1073875 /Source="Nicolas_S_feature" /locus_tag="new_1073110_1073875" /HighExp="Lbstat, Etha, T0.30H, Gly, M0t90, M40t90, M40t45, M0t45, H2O2, dia15" /AntisenseName="scoC" /AntisenseCor="-0.46322626361720198" /AntisenseRegPval="-15" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S352" downshifts complement(1073182) /Source="Nicolas_upshifts" /id="D539" /incds=1 /nref=1 /ntot=81 /MaxReadThrough="5.81117" /MaxDrop="2.1632" /score="-6.0983333" /energy="-12.3" /TU="U801" /idTUdmin="U801" /TUdmin="-550" /isTUend="FALSE" promotor_-35 1073713..1073717 /Source="Nicolas_upshift_promotors" /id="U800" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.632367632367632" /psig="0.177822177822178" /xcortree=3100 /SigmaFactorBS="agagcttctttcacatcatagggcggttccactcgaTTCATt acgtcaCCTGCTTCTCTTTTtctttttctctattatgccaataaaataaagattaata a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1073725..1073738 /Source="Nicolas_upshift_promotors" /id="U800" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.632367632367632" /psig="0.177822177822178" /xcortree=3100 /SigmaFactorBS="agagcttctttcacatcatagggcggttccactcgaTTCATt acgtcaCCTGCTTCTCTTTTtctttttctctattatgccaataaaataaagattaata a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1073737 /Source="Nicolas_upshifts" /id="U800" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.632367632367632" /psig="0.177822177822178" /xcortree=3100 /SigmaFactorBS="agagcttctttcacatcatagggcggttccactcgaTTCATt acgtcaCCTGCTTCTCTTTTtctttttctctattatgccaataaaataaagattaata a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 complement(1073742..1073761) /Source="Nicolas_upshift_promotors" /id="U801" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.656343656343656" /psig="0.98901098901099" /xcortree=2944 /SigmaFactorBS="cgtcgcaatggtttgtgaatttattaaaaaattcttacattt tcatCTTTattaatctttatttTATTGGCATAATAGAGAAAAagaaaaagagaagcag g" /listShort="scoC, S351" /listLong="yhaJ, S350, S348" /label="promotor_-10" upshifts complement(1073765) /Source="Nicolas_upshifts" /id="U801" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.656343656343656" /psig="0.98901098901099" /xcortree=2944 /SigmaFactorBS="cgtcgcaatggtttgtgaatttattaaaaaattcttacattt tcatCTTTattaatctttatttTATTGGCATAATAGAGAAAAagaaaaagagaagcag g" /listShort="scoC, S351" /listLong="yhaJ, S350, S348" promotor_-35 complement(1073776..1073779) /Source="Nicolas_upshift_promotors" /id="U801" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.656343656343656" /psig="0.98901098901099" /xcortree=2944 /SigmaFactorBS="cgtcgcaatggtttgtgaatttattaaaaaattcttacattt tcatCTTTattaatctttatttTATTGGCATAATAGAGAAAAagaaaaagagaagcag g" /listShort="scoC, S351" /listLong="yhaJ, S350, S348" /label="promotor_-35" downshifts 1073832 /Source="Nicolas_upshifts" /id="D540" /incds=0 /nref=1 /ntot=124 /MaxReadThrough="3.007" /MaxDrop="2.86547" /score="17.8486533" /energy="-7.1" /TU="U799,U800" /idTUdmin="U799" /TUdmin="-22" /isTUend="TRUE" CDS complement(1073895..1074251) /gene="yhaH" /locus_tag="BSU_10000" /old_locus_tag="BSU10000" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 11429463; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative membrane protein; acid tolerance protein" /protein_id="NP_388881.1" /db_xref="EnsemblGenomes-Gn:BSU10000" /db_xref="EnsemblGenomes-Tr:CAB12840" /db_xref="GOA:O07516" /db_xref="InterPro:IPR024623" /db_xref="InterPro:IPR036191" /db_xref="SubtiList:BG12984" /db_xref="UniProtKB/Swiss-Prot:O07516" /translation="MASGRSLLTGLFVGGIIGGAAVLLTAPSSGKQLREKMKTNYDSF EETIKRLKSDGLALKDQLIKAAKESTDVIKDVGGELQTSIKKWQEEIKPHQQDLQKEI ADIEEKIRQLEKTLQN*" gene complement(1073895..1074251) /gene="yhaH" /locus_tag="BSU_10000" /old_locus_tag="BSU10000" downshifts complement(1073899) /Source="Nicolas_upshifts" /id="D541" /incds=0 /nref=254 /ntot=287 /MaxReadThrough="1.65317" /MaxDrop="7.37381" /score="10.8990112" /energy="-7.9" /TU="NA" /idTUdmin="U804" /TUdmin=9 /isTUend="TRUE" promotor_-35 1074328..1074333 /Source="Nicolas_upshift_promotors" /id="U803" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=1168 /SigmaFactorBS="ttcagcatttttcatttttgttgaaagcctgaacttctaTAC ATAgcttgctttattttaGCATATTTTTTAAGTGAAAaggagggagaaggttgtctgt c" /listShort="yhzF, S354" /GFF_Attribute="listLong" /label="promotor_-35" misc_feature complement(1074334..1074353) /Source="Nicolas_upshift_promotors" /id="U802" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.998001998001998" /psig=1 /xcortree=1914 /SigmaFactorBS="aggataatacaatcaaaaagacagacaaccttctccctcctt ttcacttaaaaaaTATGCTAAAATAAAGCAAGCtatgtatagaagttcaggctttcaa c" /listShort="yhaH" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(1074348) /Source="Nicolas_upshifts" /id="U802" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.998001998001998" /psig=1 /xcortree=1914 /SigmaFactorBS="aggataatacaatcaaaaagacagacaaccttctccctcctt ttcacttaaaaaaTATGCTAAAATAAAGCAAGCtatgtatagaagttcaggctttcaa c" /listShort="yhaH" /GFF_Attribute="listLong" promotor_-10 1074349..1074367 /Source="Nicolas_upshift_promotors" /id="U803" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=1168 /SigmaFactorBS="ttcagcatttttcatttttgttgaaagcctgaacttctaTAC ATAgcttgctttattttaGCATATTTTTTAAGTGAAAaggagggagaaggttgtctgt c" /listShort="yhzF, S354" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1074349 /Source="Nicolas_upshifts" /id="U803" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=1168 /SigmaFactorBS="ttcagcatttttcatttttgttgaaagcctgaacttctaTAC ATAgcttgctttattttaGCATATTTTTTAAGTGAAAaggagggagaaggttgtctgt c" /listShort="yhzF, S354" /GFF_Attribute="listLong" S_feature complement(1074350..1074613) /Source="Nicolas_S_feature" /locus_tag="new_1074350_1074613_c" /HighExp="Etha, Salt, HiTm, Heat, Diami, Sw, Gly, S1, MG 10, MG 60" /AntisenseName="yhzF" /AntisenseCor="-0.69425315975357205" /AntisenseRegPval="-39.299999999999997" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA, SigA" /TUshortPSig="0.969, 0.962, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S353" CDS 1074381..1074572 /gene="yhzF" /locus_tag="BSU_10009" /old_locus_tag="BSU10009" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="membrane protein of unknown function" /protein_id="YP_003097700.1" /db_xref="EnsemblGenomes-Gn:BSU10009" /db_xref="EnsemblGenomes-Tr:CAX52588" /db_xref="GOA:C0H3Y3" /db_xref="UniProtKB/Swiss-Prot:C0H3Y3" /translation="MSVFLIVLSCITLAFASGAVYYIKLLSQAASYPPKRVIRQKALV CSTGTAFTLCLIFFTKLLA*" gene 1074381..1074572 /gene="yhzF" /locus_tag="BSU_10009" /old_locus_tag="BSU10009" S_feature 1074573..1076008 /Source="Nicolas_S_feature" /locus_tag="new_1074573_1076008" /HighExp="S3, S8, S4, S6, S7, T5.0H, C30, S5, T4.0H, T3.30H" /AntisenseName="trpP" /AntisenseCor="-0.20038256384636899" /AntisenseRegPval="-3" /CDS_PredictionProba="NA" /TUshortSig="SigEF" /TUshortPSig="0.998" /TUlongSig="NA" /TUlongPSig="NA" /label="S354" CDS complement(1074646..1075164) /gene="trpP" /locus_tag="BSU_10010" /old_locus_tag="BSU10010" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:10735881, 14702295, 15849754, 16850406, 16879415, 17114263" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10735881, 14702295, 15849754, 16850406, 16879415, 17114263; Product type t : transporter" /codon_start=1 /transl_table=11 /product="tryptophan transporter or sensor" /protein_id="NP_388882.2" /db_xref="EnsemblGenomes-Gn:BSU10010" /db_xref="EnsemblGenomes-Tr:CAB12841" /db_xref="GOA:O07515" /db_xref="InterPro:IPR031360" /db_xref="SubtiList:BG12983" /db_xref="UniProtKB/Swiss-Prot:O07515" /translation="MKTKELVIMALFAAIGAALHSIIPPFLGGMKPDMMLIMMFMGIL LFPRVQNVLVIGIVTGIISALTTAFPAGQIPNIIDKPVSAFLFFSLFLLFRKSRKTGA AAVLTVIGTILSGIVFLSSALLIVGLPGGFAALFAAVVLPAAVLNTISMIIIYPIVQT ILRRSSFMEAAK*" gene complement(1074646..1075164) /gene="trpP" /locus_tag="BSU_10010" /old_locus_tag="BSU10010" downshifts complement(1074658) /Source="Nicolas_upshifts" /id="D542" /incds=0 /nref=105 /ntot=253 /MaxReadThrough="6.00956" /MaxDrop="4.62812" /score="24.5949542" /energy="-12.8" /TU="U804,U805,U806" /idTUdmin="U804" /TUdmin="-750" /isTUend="FALSE" S_feature complement(1075165..1075252) /Source="Nicolas_S_feature" /locus_tag="new_1075165_1075252_c" /HighExp="C90, B60, S1, GM 15, MG 45, MG-0.2, Etha, Lbtran, MG 25, MG t5" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA, SigA" /TUshortPSig="0.969, 0.962, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S355" promotor_-10 complement(1075244..1075263) /Source="Nicolas_upshift_promotors" /id="U804" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.541458541458541" /psig="0.969030969030969" /xcortree=591 /SigmaFactorBS="aaattccagcaggaaaatgagtaaaaagTCTGGCTAtgcaaa ccgtccgTTTGGTATACTGTTTGCATAacacattctgtaaagccttcgcaataaatga t" /listShort="S355, trpP, S353, yhaH" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1075252) /Source="Nicolas_upshifts" /id="U804" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.541458541458541" /psig="0.969030969030969" /xcortree=591 /SigmaFactorBS="aaattccagcaggaaaatgagtaaaaagTCTGGCTAtgcaaa ccgtccgTTTGGTATACTGTTTGCATAacacattctgtaaagccttcgcaataaatga t" /listShort="S355, trpP, S353, yhaH" /GFF_Attribute="listLong" promotor_-35 complement(1075277..1075284) /Source="Nicolas_upshift_promotors" /id="U804" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.541458541458541" /psig="0.969030969030969" /xcortree=591 /SigmaFactorBS="aaattccagcaggaaaatgagtaaaaagTCTGGCTAtgcaaa ccgtccgTTTGGTATACTGTTTGCATAacacattctgtaaagccttcgcaataaatga t" /listShort="S355, trpP, S353, yhaH" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(1075289..1076368) /gene="serC" /locus_tag="BSU_10020" /old_locus_tag="BSU10020" /EC_number="2.6.1.52" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:4337849, 16233211" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 4337849, 16233211; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="phosphoserine aminotransferase" /protein_id="NP_388883.1" /db_xref="EnsemblGenomes-Gn:BSU10020" /db_xref="EnsemblGenomes-Tr:CAB12842" /db_xref="GOA:P80862" /db_xref="InterPro:IPR000192" /db_xref="InterPro:IPR015421" /db_xref="InterPro:IPR015422" /db_xref="InterPro:IPR015424" /db_xref="InterPro:IPR020578" /db_xref="InterPro:IPR022278" /db_xref="SubtiList:BG12673" /db_xref="UniProtKB/Swiss-Prot:P80862" /translation="MERTTNFNAGPAALPLEVLQKAQKEFIDFNESGMSVMELSHRSK EYEAVHQKAKSLLIELMGIPEDYDILFLQGGASLQFSMLPMNFLTPEKTAHFVMTGAW SEKALAETKLFGNTSITATSETDNYSYIPEVDLTDVKDGAYLHITSNNTIFGTQWQEF PNSPIPLVADMSSDILSRKIDVSKFDVIYGGAQKNLGPSGVTVVIMKKSWLQNENANV PKILKYSTHVKADSLYNTPPTFAIYMLSLVLEWLKENGGVEAVEQRNEQKAQVLYSCI DESNGFYKGHARKDSRSRMNVTFTLRDDELTKTFVQKAKDAKMIGLGGHRSVGGCRAS IYNAVSLEDCEKLAAFMKKFQQENE*" gene complement(1075289..1076368) /gene="serC" /locus_tag="BSU_10020" /old_locus_tag="BSU10020" misc_feature complement(1076407..1076426) /Source="Nicolas_upshift_promotors" /id="U805" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.772227772227772" /psig="0.962037962037962" /xcortree=3059 /SigmaFactorBS="atccgtcaatttcttttgataattctaattttttatcaaaaa actgaattttTGTGATAGGATAATTGTATTattttatacattaacgtggaaaacaggg a" /listShort="serC, S355, trpP, S353, yhaH" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(1076418) /Source="Nicolas_upshifts" /id="U805" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.772227772227772" /psig="0.962037962037962" /xcortree=3059 /SigmaFactorBS="atccgtcaatttcttttgataattctaattttttatcaaaaa actgaattttTGTGATAGGATAATTGTATTattttatacattaacgtggaaaacaggg a" /listShort="serC, S355, trpP, S353, yhaH" /GFF_Attribute="listLong" S_feature complement(1076420..1076501) /Source="Nicolas_S_feature" /locus_tag="new_1076420_1076501_c" /HighExp="Etha, dia15, H2O2, LBGtran, G135, G180, dia5, G150, Lbexp, M0t45" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S356" CDS complement(1076515..1076952) /gene="hinT" /locus_tag="BSU_10030" /old_locus_tag="BSU10030" /EC_number="3.6.1.29" /EC_number="3.6.1.-" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 9579061, 15703176, 16934294, 17217311, 26181368, 28516732; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="promiscuous Hit-family phosphohydrolase, adenosine phosphoramidase" /protein_id="NP_388884.1" /db_xref="EnsemblGenomes-Gn:BSU10030" /db_xref="EnsemblGenomes-Tr:CAB12843" /db_xref="GOA:O07513" /db_xref="InterPro:IPR001310" /db_xref="InterPro:IPR011146" /db_xref="InterPro:IPR019808" /db_xref="InterPro:IPR036265" /db_xref="PDB:1Y23" /db_xref="SubtiList:BG12607" /db_xref="UniProtKB/Swiss-Prot:O07513" /translation="MHCAENCIFCKIIAGDIPSAKVYEDEHVLAFLDISQVTKGHTLV IPKTHIENVYEFTDELAKQYFHAVPKIARAIRDEFEPIGLNTLNNNGEKAGQSVFHYH MHIIPRYGKGDGFGAVWKTHADDYKPEDLQNISSSIAKRLASS*" gene complement(1076515..1076952) /gene="hinT" /locus_tag="BSU_10030" /old_locus_tag="BSU10030" downshifts complement(1076546) /Source="Nicolas_upshifts" /id="D543" /incds=0 /nref=187 /ntot=248 /MaxReadThrough="4.31506" /MaxDrop="5.61862" /score="-0.366845751" /energy="-8.6" /TU="U806" /idTUdmin="U807" /TUdmin=4 /isTUend="TRUE" promotor_-10 complement(1076985..1077004) /Source="Nicolas_upshift_promotors" /id="U806" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.576423576423576" /psig=1 /xcortree=2360 /SigmaFactorBS="tctgcattcagggtgaacgctcgccgttcatcctGTTTTCTA ttttctgcatttcTGTGGTACGATGAATGTATAcatactaaacaatttcataaggagg a" /listShort="hinT, S356, serC, S355, trpP, S353, yhaH" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1076999) /Source="Nicolas_upshifts" /id="U806" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.576423576423576" /psig=1 /xcortree=2360 /SigmaFactorBS="tctgcattcagggtgaacgctcgccgttcatcctGTTTTCTA ttttctgcatttcTGTGGTACGATGAATGTATAcatactaaacaatttcataaggagg a" /listShort="hinT, S356, serC, S355, trpP, S353, yhaH" /GFF_Attribute="listLong" downshifts 1077002 /Source="Nicolas_upshifts" /id="D544" /incds=0 /nref=1 /ntot=3 /MaxReadThrough="2.3752" /MaxDrop="3.02008" /score="-3.56654132" /energy="-13.3" /TU="NA" /idTUdmin="U803" /TUdmin=1034 /isTUend="FALSE" promotor_-35 complement(1077018..1077025) /Source="Nicolas_upshift_promotors" /id="U806" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.576423576423576" /psig=1 /xcortree=2360 /SigmaFactorBS="tctgcattcagggtgaacgctcgccgttcatcctGTTTTCTA ttttctgcatttcTGTGGTACGATGAATGTATAcatactaaacaatttcataaggagg a" /listShort="hinT, S356, serC, S355, trpP, S353, yhaH" /GFF_Attribute="listLong" /label="promotor_-35" S_feature complement(1077024..1077320) /Source="Nicolas_S_feature" /locus_tag="new_1077024_1077320_c" /HighExp="S7, S8, S6, S5, BT, ferm, nit, G/S, S4, Pyr" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigGF" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S357" downshifts complement(1077067) /Source="Nicolas_upshifts" /id="D545" /incds=0 /nref=40 /ntot=72 /MaxReadThrough="3.07347" /MaxDrop="7.69075" /score="9.88617558" /energy="-14.2" /TU="U807" /idTUdmin="U807" /TUdmin="-517" /isTUend="FALSE" promotor_-10 complement(1077318..1077329) /Source="Nicolas_upshift_promotors" /id="U807" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=832 /SigmaFactorBS="aaacaattcccttttaacaaatgatgaatttgctGTCATAAa gagacagggttctGGACATCATAAAagttgtagaggaaaagcatatcaactgaaaaat g" /listShort="S357, hinT" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1077324) /Source="Nicolas_upshifts" /id="U807" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=832 /SigmaFactorBS="aaacaattcccttttaacaaatgatgaatttgctGTCATAAa gagacagggttctGGACATCATAAAagttgtagaggaaaagcatatcaactgaaaaat g" /listShort="S357, hinT" /GFF_Attribute="listLong" promotor_-35 complement(1077344..1077350) /Source="Nicolas_upshift_promotors" /id="U807" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=832 /SigmaFactorBS="aaacaattcccttttaacaaatgatgaatttgctGTCATAAa gagacagggttctGGACATCATAAAagttgtagaggaaaagcatatcaactgaaaaat g" /listShort="S357, hinT" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1077380..1077387 /Source="Nicolas_upshift_promotors" /id="U808" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.553446553446553" /psig=1 /xcortree=1921 /SigmaFactorBS="cagcaaattcatcatttgttaaaagggaatTGTTTCAAatca ggccttgttTTTGGTACTATGAAGAAAAAcactataaggggagaaactatgtctctgc t" /listShort="ecsA, ecsB, ecsC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1077401..1077420 /Source="Nicolas_upshift_promotors" /id="U808" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.553446553446553" /psig=1 /xcortree=1921 /SigmaFactorBS="cagcaaattcatcatttgttaaaagggaatTGTTTCAAatca ggccttgttTTTGGTACTATGAAGAAAAAcactataaggggagaaactatgtctctgc t" /listShort="ecsA, ecsB, ecsC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1077410 /Source="Nicolas_upshifts" /id="U808" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.553446553446553" /psig=1 /xcortree=1921 /SigmaFactorBS="cagcaaattcatcatttgttaaaagggaatTGTTTCAAatca ggccttgttTTTGGTACTATGAAGAAAAAcactataaggggagaaactatgtctctgc t" /listShort="ecsA, ecsB, ecsC" /GFF_Attribute="listLong" CDS 1077440..1078183 /gene="ecsA" /locus_tag="BSU_10040" /old_locus_tag="BSU10040" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:8581172, 10027970, 11807061, 18599827, 26735940" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8581172, 10027970, 11807061, 18599827, 26735940; Product type t : transporter" /codon_start=1 /transl_table=11 /product="ABC transporter (ATP-binding protein)" /protein_id="NP_388885.1" /db_xref="EnsemblGenomes-Gn:BSU10040" /db_xref="EnsemblGenomes-Tr:CAB12844" /db_xref="GOA:P55339" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG11516" /db_xref="UniProtKB/Swiss-Prot:P55339" /translation="MSLLSVKDLTGGYTRNPVLKNVSFTLEPNQIVGLIGLNGAGKST TIRHIIGLMDPHKGSIELNGKTFAEDPEGYRSQFTYIPETPVLYEELTLMEHLELTAM AYGLSKETMEKRLPPLLKEFRMEKRLKWFPAHFSKGMKQKVMIMCAFLAEPALYIIDE PFLGLDPLAINALLERMNEAKKGGASVLMSTHILATAERYCDSFIILHNGEVRARGTL SELREQFGMKDAALDDLYLELTKEDAGHE*" gene 1077440..1078183 /gene="ecsA" /locus_tag="BSU_10040" /old_locus_tag="BSU10040" CDS 1078176..1079402 /gene="ecsB" /locus_tag="BSU_10050" /old_locus_tag="BSU10050" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:8581172, 10027970, 15175311, 15849754, 16850406, 18599827, 21665535, 26735940" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8581172, 10027970, 15175311, 15849754, 16850406, 18599827, 21665535, 26735940; Product type t: transporter" /codon_start=1 /transl_table=11 /product="ABC transporter (permease subunit)" /protein_id="NP_388886.1" /db_xref="EnsemblGenomes-Gn:BSU10050" /db_xref="EnsemblGenomes-Tr:CAB12845" /db_xref="GOA:P55340" /db_xref="InterPro:IPR010288" /db_xref="SubtiList:BG11517" /db_xref="UniProtKB/Swiss-Prot:P55340" /translation="MNNMLDIWQSRLQEHIKETRTYMKYMLNDHLVIVLIFFLAGAAS WYSKWIRDIPAHFPSFWVMAVLFSLVLTSSYVRTLLKEADLVFLLPLEAKMEPYLKQA FVYSYVSQLFPLIALSIVAMPLYFAVTPGASLVSYAAVFVQLLLLKAWNQVMEWRTTF QNDRSMKRMDVIIRFAANTLVLYFVFQSVYMYALLVYVIMAVLYLYMSSAAKRKTFKW ESHIESELRRKQRFYRIANLFTDVPHLRKQAKRRAYLDFLLRLVPFEQRKTFAYMFTR AFLRSSDYLGILVRLTIVFALIIMYVSASPLIAAVLTVFAIFITGIQLLPLFGHFDHL ALQELYPVQKETKLKSYFSLLKTALSIQALLMSVASAYAAGLTGFLYALIGSAVLIFV VLPAYMTTRLKKHGKL*" gene 1078176..1079402 /gene="ecsB" /locus_tag="BSU_10050" /old_locus_tag="BSU10050" promotor_-10 complement(1078735..1078753) /Source="Nicolas_upshift_promotors" /id="U809" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1033 /SigmaFactorBS="tttgctgcggaagacatatacagataaagaacagccATAATG acatagacgagaagcGCATACATATAAACAGATTggaaaacaaaataaagaacgagtg t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1078750) /Source="Nicolas_upshifts" /id="U809" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1033 /SigmaFactorBS="tttgctgcggaagacatatacagataaagaacagccATAATG acatagacgagaagcGCATACATATAAACAGATTggaaaacaaaataaagaacgagtg t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(1078769..1078774) /Source="Nicolas_upshift_promotors" /id="U809" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1033 /SigmaFactorBS="tttgctgcggaagacatatacagataaagaacagccATAATG acatagacgagaagcGCATACATATAAACAGATTggaaaacaaaataaagaacgagtg t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" CDS 1079422..1080132 /gene="ecsC" /locus_tag="BSU_10060" /old_locus_tag="BSU10060" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 8581172, 10027970; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative hydrolase" /protein_id="NP_388887.1" /db_xref="EnsemblGenomes-Gn:BSU10060" /db_xref="EnsemblGenomes-Tr:CAB12846" /db_xref="InterPro:IPR024787" /db_xref="SubtiList:BG11518" /db_xref="UniProtKB/Swiss-Prot:P55341" /translation="MTDNQLLMQEALEWKMHFLRKDSMFERFSKRVQTKVNERIPEKI HTVVTESVKKMVEATMAGSNIITYKKDTSALSLSEKNELAKKTIVSYQKVAAAEGVGT GAGGIFLSIADFPLLLSIKMKCLFTLSSIYGFDVKDAQERIFLLLVFQLAFSSDDGRK SLFSVIENWETEKKSIDWRVFQQEYRDYIDVVKLFQLLPGVGAAVGGIANYKLLAQLG ETARHVFHLRILKETAGE*" gene 1079422..1080132 /gene="ecsC" /locus_tag="BSU_10060" /old_locus_tag="BSU10060" downshifts 1080096 /Source="Nicolas_upshifts" /id="D546" /incds=0 /nref=78 /ntot=231 /MaxReadThrough="1.36097" /MaxDrop="4.78417" /score="28.5337351" /energy="-14.6" /TU="NA" /idTUdmin="U808" /TUdmin="-8" /isTUend="TRUE" CDS complement(1080150..1081340) /gene="sndC" /locus_tag="BSU_10070" /old_locus_tag="BSU10070" /EC_number="3.5.1.-" /experiment="publication(s) with functional evidences, PMID:23944997" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 23944997; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="N-acetyl amino acid acetylase, promiscuous activity" /protein_id="NP_388888.2" /db_xref="EnsemblGenomes-Gn:BSU10070" /db_xref="EnsemblGenomes-Tr:CAB12847" /db_xref="GOA:O07598" /db_xref="InterPro:IPR002933" /db_xref="InterPro:IPR011650" /db_xref="InterPro:IPR017439" /db_xref="InterPro:IPR036264" /db_xref="SubtiList:BG12982" /db_xref="UniProtKB/Swiss-Prot:O07598" /translation="MSISTLQKEINKQLDGCFEEMVEIRRHFHMYPELSFQEEKTAAF IASYYESLGVPIRTNVGGRGVLANIEGSEPGPTVALRADFDALPIQDEKDVPYASKVP GVMHACGHDGHTAALLAVAKVLHQNRHELKGTFVMIHQHAEEYYPGGAKPMIDDGCLE NTDVIFGTHLWATEPLGTILCRPGAVMAAADRFTIKVFGKGGHGAHPHDTKDAVLIGS QIVSSLQHIVSRKVNPIQSAVISTGSFIADNPFNVIADQAVLIGTARSFDENVRDILE KEIEAVVKGICSMHGASYEYTYEQGYPAVVNHPAETNHLVSTAKNTEGVQQVIDGEPQ MGGEDFAYYLQNVKGTFFFTGAAPEQPERVYSHHHPKFDINEKAMLTAAKVLAGAAIT YHQL*" gene complement(1080150..1081340) /gene="sndC" /locus_tag="BSU_10070" /old_locus_tag="BSU10070" downshifts complement(1080160) /Source="Nicolas_upshifts" /id="D547" /incds=0 /nref=11 /ntot=162 /MaxReadThrough="3.12546" /MaxDrop="4.15559" /score="-4.78420642" /energy="-14.6" /TU="U810" /idTUdmin="U811" /TUdmin="-2" /isTUend="TRUE" downshifts complement(1080225) /Source="Nicolas_upshifts" /id="D548" /incds=1 /nref=25 /ntot=206 /MaxReadThrough="4.92378" /MaxDrop="3.21645" /score="-4.78420642" /energy="-14.6" /TU="U810,U811" /idTUdmin="U811" /TUdmin="-67" /isTUend="FALSE" promotor_-10 complement(1081364..1081383) /Source="Nicolas_upshift_promotors" /id="U810" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.498501498501498" /psig=1 /xcortree=2900 /SigmaFactorBS="gtgacaaccctcgcagctgtgatgatgctttaaaacagcatg aGTTGAAatattcagactttTTCTATACAATCATGGAAAAgcatagaaaagggggaag c" /listShort="yhaA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1081385) /Source="Nicolas_upshifts" /id="U810" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.498501498501498" /psig=1 /xcortree=2900 /SigmaFactorBS="gtgacaaccctcgcagctgtgatgatgctttaaaacagcatg aGTTGAAatattcagactttTTCTATACAATCATGGAAAAgcatagaaaagggggaag c" /listShort="yhaA" /GFF_Attribute="listLong" promotor_-35 complement(1081397..1081402) /Source="Nicolas_upshift_promotors" /id="U810" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.498501498501498" /psig=1 /xcortree=2900 /SigmaFactorBS="gtgacaaccctcgcagctgtgatgatgctttaaaacagcatg aGTTGAAatattcagactttTTCTATACAATCATGGAAAAgcatagaaaagggggaag c" /listShort="yhaA" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(1081413..1082804) /gene="yhfA" /locus_tag="BSU_10080" /old_locus_tag="BSU10080" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406, 12107147; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative transporter" /protein_id="NP_388889.1" /db_xref="EnsemblGenomes-Gn:BSU10080" /db_xref="EnsemblGenomes-Tr:CAB12848" /db_xref="GOA:O07599" /db_xref="SubtiList:BG13047" /db_xref="UniProtKB/Swiss-Prot:O07599" /translation="MMEVGILPVHVLYVFFIGAIILFMLLRKDTTFISLFGIFIISLW ASHSLSASVSSLFHSFIYAAGELLPTIFIICFIVSMSDLLTKTGINEAMISPFASLVR GPVTAYWLIGGLMFAISLFFWPSPGVALIGAVLLPAAARAGLTPLAAAMAMNLFGHGF ALSGDFVIQAAPKLTADAAGIPVGDVVSASIPLVLIMGVTTTTAAFIMIQRERKKQEH PTSFSPVLSGEQDNSLYLPKRLRSILAFLIPLAFLADIACMLLFNLQGNDATALIGGS AICILFTVHFFVYKHKGLEKITGYFIDGFKFGFKVFGPVIPIAAFFYLGDSGYESILG TSLPKGSHGIVNDLGIALSHMMPMSKELAATALTAAGAITGLDGSGFSGISLAGSIAK LFSSALHADPAILTALGQISAIWVGGGTLVPWALIPAAAICKVDPFELARKNFIPVAI GLLVTTLAAVMML*" gene complement(1081413..1082804) /gene="yhfA" /locus_tag="BSU_10080" /old_locus_tag="BSU10080" promotor_-10 complement(1082815..1082834) /Source="Nicolas_upshift_promotors" /id="U811" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1283 /SigmaFactorBS="ttccatcataaccctcccctctgtCCCGGCACCTtccgcccg cctaTGAATAATCTGTAAGCGGAAggagtgatcgatgatggaagtcgggattttgcct g" /listShort="yhfA, yhaA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1082820) /Source="Nicolas_upshifts" /id="U811" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1283 /SigmaFactorBS="ttccatcataaccctcccctctgtCCCGGCACCTtccgcccg cctaTGAATAATCTGTAAGCGGAAggagtgatcgatgatggaagtcgggattttgcct g" /listShort="yhfA, yhaA" /GFF_Attribute="listLong" promotor_-35 complement(1082847..1082856) /Source="Nicolas_upshift_promotors" /id="U811" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1283 /SigmaFactorBS="ttccatcataaccctcccctctgtCCCGGCACCTtccgcccg cctaTGAATAATCTGTAAGCGGAAggagtgatcgatgatggaagtcgggattttgcct g" /listShort="yhfA, yhaA" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(1082870..1083184) /gene="yhgB" /locus_tag="BSU_10090" /old_locus_tag="BSU10090" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="NP_388890.1" /db_xref="EnsemblGenomes-Gn:BSU10090" /db_xref="EnsemblGenomes-Tr:CAB12849" /db_xref="SubtiList:BG10426" /db_xref="UniProtKB/Swiss-Prot:P38048" /translation="MKHTCPVCGFKDWLNRHMIMKAIILMKSARAAVFSSDLMSTRCS TRITHIEPSESIIAYRKNWLAEGCVIFSPECFPKHLQKANRGLRHHLIEQLKQINVHL PS*" gene complement(1082870..1083184) /gene="yhgB" /locus_tag="BSU_10090" /old_locus_tag="BSU10090" CDS complement(1083229..1083729) /gene="hmoB" /locus_tag="BSU_10100" /old_locus_tag="BSU10100" /EC_number="1.14.99.48" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:21873409, 22531134, 24582752" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 21873409, 22531134, 24582752; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="heme-degrading monooxygenase" /protein_id="NP_388891.1" /db_xref="EnsemblGenomes-Gn:BSU10100" /db_xref="EnsemblGenomes-Tr:CAB12850" /db_xref="GOA:P38049" /db_xref="InterPro:IPR007138" /db_xref="InterPro:IPR011008" /db_xref="PDB:4OZ5" /db_xref="SubtiList:BG10427" /db_xref="UniProtKB/Swiss-Prot:P38049" /translation="MKVYITYGTADFLKTIVQKHPSENILLMQGQENAILIHETNGDT VFQAPHAYEVIDQVGEIKHPGFAVLNNIAVTQEGRPLFENRFKNRAGKVENEPGFEAI RVLRPLDSDTYVILTLWETESAFQDWQQSGSYKEAHKKRDTSAGIDTTSIFSRPSYVT TYFAVE*" gene complement(1083229..1083729) /gene="hmoB" /locus_tag="BSU_10100" /old_locus_tag="BSU10100" downshifts complement(1083256) /Source="Nicolas_upshifts" /id="D549" /incds=0 /nref=145 /ntot=254 /MaxReadThrough="3.45185" /MaxDrop="5.6374" /score="15.5142908" /energy="-14.8" /TU="U812" /idTUdmin="U812" /TUdmin="-546" /isTUend="FALSE" promotor_-10 complement(1083742..1083761) /Source="Nicolas_upshift_promotors" /id="U812" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.555444555444555" /psig="0.98101898101898" /xcortree=101 /SigmaFactorBS="tatgggaaaaattgtttggaattatgttcgaagcactcgcca atAGaaacttataccattgtTTTGATATACTAGCAAGCAGgaggtggctgatatgaag g" /listShort="yhgC, yhgB, yhfA" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 1083744..1083748 /Source="Nicolas_upshift_promotors" /id="U813" /multdbtbs="SigA" /comp="M16" /sig="SigA" /pcomp="0.953046953046953" /psig="0.957042957042957" /xcortree=1837 /SigmaFactorBS="tcccatatgtaatataaaccttcatatcagccacctcctGCT TGctagtatatcaaaacAATGGTATAAGTTTCTATTGgcgagtgcttcgaacataatt c" /listShort="pbpF, hemE, hemH, hemY" /GFF_Attribute="listLong" /label="promotor_-35" upshifts complement(1083763) /Source="Nicolas_upshifts" /id="U812" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.555444555444555" /psig="0.98101898101898" /xcortree=101 /SigmaFactorBS="tatgggaaaaattgtttggaattatgttcgaagcactcgcca atAGaaacttataccattgtTTTGATATACTAGCAAGCAGgaggtggctgatatgaag g" /listShort="yhgC, yhgB, yhfA" /GFF_Attribute="listLong" promotor_-10 1083764..1083783 /Source="Nicolas_upshift_promotors" /id="U813" /multdbtbs="SigA" /comp="M16" /sig="SigA" /pcomp="0.953046953046953" /psig="0.957042957042957" /xcortree=1837 /SigmaFactorBS="tcccatatgtaatataaaccttcatatcagccacctcctGCT TGctagtatatcaaaacAATGGTATAAGTTTCTATTGgcgagtgcttcgaacataatt c" /listShort="pbpF, hemE, hemH, hemY" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1083765 /Source="Nicolas_upshifts" /id="U813" /multdbtbs="SigA" /comp="M16" /sig="SigA" /pcomp="0.953046953046953" /psig="0.957042957042957" /xcortree=1837 /SigmaFactorBS="tcccatatgtaatataaaccttcatatcagccacctcctGCT TGctagtatatcaaaacAATGGTATAAGTTTCTATTGgcgagtgcttcgaacataatt c" /listShort="pbpF, hemE, hemH, hemY" /GFF_Attribute="listLong" promotor_-35 complement(1083778..1083779) /Source="Nicolas_upshift_promotors" /id="U812" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.555444555444555" /psig="0.98101898101898" /xcortree=101 /SigmaFactorBS="tatgggaaaaattgtttggaattatgttcgaagcactcgcca atAGaaacttataccattgtTTTGATATACTAGCAAGCAGgaggtggctgatatgaag g" /listShort="yhgC, yhgB, yhfA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1083796..1083802 /Source="Nicolas_upshift_promotors" /id="U814" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=871 /SigmaFactorBS="acaatggtataagtttctattggcgagtgcttcgAACATAAt tccaaacaattttTCCCATACTACCtttagaaaggcgaggtgagttcatgtttaagat a" /listShort="pbpF, hemE, hemH" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1083817..1083828 /Source="Nicolas_upshift_promotors" /id="U814" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=871 /SigmaFactorBS="acaatggtataagtttctattggcgagtgcttcgAACATAAt tccaaacaattttTCCCATACTACCtttagaaaggcgaggtgagttcatgtttaagat a" /listShort="pbpF, hemE, hemH" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1083822 /Source="Nicolas_upshifts" /id="U814" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=871 /SigmaFactorBS="acaatggtataagtttctattggcgagtgcttcgAACATAAt tccaaacaattttTCCCATACTACCtttagaaaggcgaggtgagttcatgtttaagat a" /listShort="pbpF, hemE, hemH" /GFF_Attribute="listLong" CDS 1083851..1085995 /gene="pbpF" /locus_tag="BSU_10110" /old_locus_tag="BSU10110" /function="16.13: Shape" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:8335642, 11567005, 22720735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8335642, 11567005, 22720735; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="penicillin-binding protein 2C (1F class) required for spore germination" /protein_id="NP_388892.2" /db_xref="EnsemblGenomes-Gn:BSU10110" /db_xref="EnsemblGenomes-Tr:CAB12851" /db_xref="GOA:P38050" /db_xref="InterPro:IPR001264" /db_xref="InterPro:IPR001460" /db_xref="InterPro:IPR012338" /db_xref="InterPro:IPR023346" /db_xref="InterPro:IPR036950" /db_xref="SubtiList:BG10428" /db_xref="UniProtKB/Swiss-Prot:P38050" /translation="MFKIKKKKLFIPIIILVLTAFLALIGYISIIFLGHYVIDEKKLI LHASSKIVDQNGDEVASLYTENREPVSINEIPKQVREAFIAVEDKRFYEHHGIDAKSV GRAVYRDILAGGKVEGGSTITQQLAKNIFLTHDKTFLRKTKEVIIAINLERDYSKDKL LEMYLNQLYFGHGVYGIQAASHYYFNKEVKDLTVSEGAVLAAIPKAPSTYSPILHPDK NKERRDTILGMMNDQGYISAKEAVTAQGRTLGLHVKKQSETPWFDSYIDLVIKEAEDK YSISGEQLLQGGYTIKVPLDSKLQKTAYQVMKEGSYYPGTDQNAEGSAVFINNKTGGV EAAIGGRDYTSKGYNRVTAVRQPGSTFKPLAVYGPAMQEKKFKPYSLLKDELQSYGDY TPKNYDSRYEGEVTMSDAITYSKNAPAVWTLNEIGVETGKSYLKANGIDIPDEGLALA LGGLEKGVSPLQLAGAFHTFAANGTYTEPFFISSIIDEDGETIADHKEEGKRVFSKQT SWNMTRMLQQVVKKGTATSGTYHGDLAGKTGSTSYTGVSGATKDAWFAGYTPKITGAV WMGYDKTDQNHYLKAGSSYPTRLFKDILTQAGETGHVFTKPKNVKELESPIELKPVKT LTADYTFKAAGLFTIELKWDAQEDDRAVYRIYVNKDGEETLLDSVEGKGSYEIPYANL FSGASYKIVPYNTQTKREGEGTDYVQPKLFSS*" gene 1083851..1085995 /gene="pbpF" /locus_tag="BSU_10110" /old_locus_tag="BSU10110" promotor_-10 complement(1083895..1083906) /Source="Nicolas_upshift_promotors" /id="U815" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.595404595404595" /psig="0.595404595404595" /xcortree=1190 /SigmaFactorBS="ataatggccgagaaaaataattgaaatatatcCTATTAAagc gagaaaagcaGTTAACACTAAAataatgataggtataaaaagtttctttttctttatc t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1083898) /Source="Nicolas_upshifts" /id="U815" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.595404595404595" /psig="0.595404595404595" /xcortree=1190 /SigmaFactorBS="ataatggccgagaaaaataattgaaatatatcCTATTAAagc gagaaaagcaGTTAACACTAAAataatgataggtataaaaagtttctttttctttatc t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(1083920..1083926) /Source="Nicolas_upshift_promotors" /id="U815" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.595404595404595" /psig="0.595404595404595" /xcortree=1190 /SigmaFactorBS="ataatggccgagaaaaataattgaaatatatcCTATTAAagc gagaaaagcaGTTAACACTAAAataatgataggtataaaaagtttctttttctttatc t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1086032..1086038 /Source="Nicolas_upshift_promotors" /id="U816" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.377622377622378" /psig="0.998001998001998" /xcortree=1606 /SigmaFactorBS="tcggcgattttttgaactttgagctacattTCTATACcattt gcctaaaaCAAGGTATAGTGTAATAAGTcaagaaatacgaacgtatggttgccgtatg a" /listShort="hemE, hemH, hemY" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1086052..1086071 /Source="Nicolas_upshift_promotors" /id="U816" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.377622377622378" /psig="0.998001998001998" /xcortree=1606 /SigmaFactorBS="tcggcgattttttgaactttgagctacattTCTATACcattt gcctaaaaCAAGGTATAGTGTAATAAGTcaagaaatacgaacgtatggttgccgtatg a" /listShort="hemE, hemH, hemY" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1086062 /Source="Nicolas_upshifts" /id="U816" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.377622377622378" /psig="0.998001998001998" /xcortree=1606 /SigmaFactorBS="tcggcgattttttgaactttgagctacattTCTATACcattt gcctaaaaCAAGGTATAGTGTAATAAGTcaagaaatacgaacgtatggttgccgtatg a" /listShort="hemE, hemH, hemY" /GFF_Attribute="listLong" CDS 1086117..1087178 /gene="hemE" /locus_tag="BSU_10120" /old_locus_tag="BSU10120" /EC_number="4.1.1.37" /function="16.2: Construct biomass (Anabolism)" /function="16.10: Respire" /experiment="publication(s) with functional evidences, PMID:10217486, 17122346" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10217486, 17122346; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="uroporphyrinogen III decarboxylase" /protein_id="NP_388893.1" /db_xref="EnsemblGenomes-Gn:BSU10120" /db_xref="EnsemblGenomes-Tr:CAB12852" /db_xref="GOA:P32395" /db_xref="InterPro:IPR000257" /db_xref="InterPro:IPR006361" /db_xref="PDB:2INF" /db_xref="SubtiList:BG10429" /db_xref="UniProtKB/Swiss-Prot:P32395" /translation="MSKRETFNETFLKAARGEKADHTPVWYMRQAGRSQPEYRKLKEK YGLFEITHQPELCAYVTRLPVEQYGVDAAILYKDIMTPLPSIGVDVEIKNGIGPVIDQ PIRSLADIEKLGQIDPEQDVPYVLETIKLLVNEQLNVPLIGFSGAPFTLASYMIEGGP SKNYNKTKAFMYSMPDAWNLLMSKLADMIIVYVKAQIEAGAKAIQIFDSWVGALNQAD YRTYIKPVMNRIFSELAKENVPLIMFGVGASHLAGDWHDLPLDVVGLDWRLGIDEARS KGITKTVQGNLDPSILLAPWEVIEQKTKEILDQGMESDGFIFNLGHGVFPDVSPEVLK KLTAFVHEYSQNKKMGQYS*" gene 1086117..1087178 /gene="hemE" /locus_tag="BSU_10120" /old_locus_tag="BSU10120" CDS 1087250..1088182 /gene="hemH" /locus_tag="BSU_10130" /old_locus_tag="BSU10130" /EC_number="4.99.1.1" /function="16.2: Construct biomass (Anabolism)" /function="16.10: Respire" /experiment="publication(s) with functional evidences, PMID:8119288, 12686546, 12761666, 16140324, 16453119, 17198378, 20543190, 21052751" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8119288, 12686546, 12761666, 16140324, 16453119, 17198378, 20543190, 21052751; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="ferrochelatase" /protein_id="NP_388894.1" /db_xref="EnsemblGenomes-Gn:BSU10130" /db_xref="EnsemblGenomes-Tr:CAB12853" /db_xref="GOA:P32396" /db_xref="InterPro:IPR001015" /db_xref="InterPro:IPR019772" /db_xref="InterPro:IPR033644" /db_xref="InterPro:IPR033659" /db_xref="PDB:1AK1" /db_xref="PDB:1C1H" /db_xref="PDB:1C9E" /db_xref="PDB:1DOZ" /db_xref="PDB:1FJI" /db_xref="PDB:1LD3" /db_xref="PDB:1N0I" /db_xref="PDB:2AC2" /db_xref="PDB:2AC4" /db_xref="PDB:2H1V" /db_xref="PDB:2H1W" /db_xref="PDB:2HK6" /db_xref="PDB:2Q2N" /db_xref="PDB:2Q2O" /db_xref="PDB:2Q3J" /db_xref="PDB:3GOQ" /db_xref="PDB:3M4Z" /db_xref="SubtiList:BG10430" /db_xref="UniProtKB/Swiss-Prot:P32396" /translation="MSRKKMGLLVMAYGTPYKEEDIERYYTHIRRGRKPEPEMLQDLK DRYEAIGGISPLAQITEQQAHNLEQHLNEIQDEITFKAYIGLKHIEPFIEDAVAEMHK DGITEAVSIVLAPHFSTFSVQSYNKRAKEEAEKLGGLTITSVESWYDEPKFVTYWVDR VKETYASMPEDERENAMLIVSAHSLPEKIKEFGDPYPDQLHESAKLIAEGAGVSEYAV GWQSEGNTPDPWLGPDVQDLTRDLFEQKGYQAFVYVPVGFVADHLEVLYDNDYECKVV TDDIGASYYRPEMPNAKPEFIDALATVVLKKLGR*" gene 1087250..1088182 /gene="hemH" /locus_tag="BSU_10130" /old_locus_tag="BSU10130" CDS 1088197..1089609 /gene="hemY" /locus_tag="BSU_10140" /old_locus_tag="BSU10140" /EC_number="1.3.3.4" /function="16.10: Respire" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:9217019, 9784236, 10498703, 20543190" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9217019, 9784236, 10498703, 20543190; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="promiscuous protoporphyrinogen IX and coproporphyrinogen III oxidase" /protein_id="NP_388895.1" /db_xref="EnsemblGenomes-Gn:BSU10140" /db_xref="EnsemblGenomes-Tr:CAB12854" /db_xref="GOA:P32397" /db_xref="InterPro:IPR002937" /db_xref="InterPro:IPR004572" /db_xref="InterPro:IPR036188" /db_xref="PDB:3I6D" /db_xref="SubtiList:BG10431" /db_xref="UniProtKB/Swiss-Prot:P32397" /translation="MSDGKKHVVIIGGGITGLAAAFYMEKEIKEKNLPLELTLVEASP RVGGKIQTVKKDGYIIERGPDSFLERKKSAPQLVKDLGLEHLLVNNATGQSYVLVNRT LHPMPKGAVMGIPTKIAPFVSTGLFSLSGKARAAMDFILPASKTKDDQSLGEFFRRRV GDEVVENLIEPLLSGIYAGDIDKLSLMSTFPQFYQTEQKHRSLILGMKKTRPQGSGQQ LTAKKQGQFQTLSTGLQTLVEEIEKQLKLTKVYKGTKVTKLSHSGSCYSLELDNGVTL DADSVIVTAPHKAAAGMLSELPAISHLKNMHSTSVANVALGFPEGSVQMEHEGTGFVI SRNSDFAITACTWTNKKWPHAAPEGKTLLRAYVGKAGDESIVDLSDNDIINIVLEDLK KVMNINGEPEMTCVTRWHESMPQYHVGHKQRIKELREALASAYPGVYMTGASFEGVGI PDCIDQGKAAVSDALTYLFS*" gene 1088197..1089609 /gene="hemY" /locus_tag="BSU_10140" /old_locus_tag="BSU10140" downshifts 1088200 /Source="Nicolas_upshifts" /id="D550" /incds=0 /nref=1 /ntot=19 /MaxReadThrough="7.68191" /MaxDrop="2.667" /score="28.7532434" /energy="-11.6" /TU="U813,U816" /idTUdmin="U814" /TUdmin=0 /isTUend="TRUE" downshifts 1089586 /Source="Nicolas_upshifts" /id="D551" /incds=0 /nref=195 /ntot=254 /MaxReadThrough="2.9859" /MaxDrop="6.7703" /score="28.7532434" /energy="-11.6" /TU="NA" /idTUdmin="U813" /TUdmin=0 /isTUend="TRUE" promotor_-35 1089670..1089677 /Source="Nicolas_upshift_promotors" /id="U817" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.825174825174825" /psig=1 /xcortree=2648 /SigmaFactorBS="tttgatgtgcaatggcaatattgtgtaaaaaatgATTGAATT gaacagcaggttaTGATACATTTGCATATGTACttaatgactaaaatgttcaaacggt c" /listShort="yhgD, S358, yhgE" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1089691..1089710 /Source="Nicolas_upshift_promotors" /id="U817" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.825174825174825" /psig=1 /xcortree=2648 /SigmaFactorBS="tttgatgtgcaatggcaatattgtgtaaaaaatgATTGAATT gaacagcaggttaTGATACATTTGCATATGTACttaatgactaaaatgttcaaacggt c" /listShort="yhgD, S358, yhgE" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1089696 /Source="Nicolas_upshifts" /id="U817" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.825174825174825" /psig=1 /xcortree=2648 /SigmaFactorBS="tttgatgtgcaatggcaatattgtgtaaaaaatgATTGAATT gaacagcaggttaTGATACATTTGCATATGTACttaatgactaaaatgttcaaacggt c" /listShort="yhgD, S358, yhgE" /GFF_Attribute="listLong" CDS 1089755..1090330 /gene="yhgD" /locus_tag="BSU_10150" /old_locus_tag="BSU10150" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1c: Function from experimental evidences in the studied genus; PubMedId: 15944459, 23695570; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator of unknown target" /protein_id="NP_388896.1" /db_xref="EnsemblGenomes-Gn:BSU10150" /db_xref="EnsemblGenomes-Tr:CAB12855" /db_xref="GOA:P32398" /db_xref="InterPro:IPR001647" /db_xref="InterPro:IPR009057" /db_xref="InterPro:IPR023772" /db_xref="InterPro:IPR036271" /db_xref="SubtiList:BG10432" /db_xref="UniProtKB/Swiss-Prot:P32398" /translation="MSIDRKKLILEAATKSFTQFGYKATTMDLVAKLANVGKGTIYTF FKNKEELFDEIFTTLLKEMKQKADEAMEPSLPFHENVHRALFAILEFRKTHQLTIKIF QENAEIGTMAVQEVIQKMERSILSYIKSKIEDGIKSGAIKPCDPELTAFVMLKLYIAL IFDWEKQHPPLDKETIAGLLELYVVKGLSAN*" gene 1089755..1090330 /gene="yhgD" /locus_tag="BSU_10150" /old_locus_tag="BSU10150" promotor_-35 1090074..1090077 /Source="Nicolas_upshift_promotors" /id="U818" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.731268731268731" /psig="0.731268731268731" /xcortree=140 /SigmaFactorBS="aaacacatcagctgacgattaaaattttccaagagaatgccg AGATtggtacaatggcagttCAGGAAGTGATCCAGAAAATggagcgatccatcctgtc t" /listShort="S358, yhgE" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 1090092 /Source="Nicolas_upshifts" /id="U818" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.731268731268731" /psig="0.731268731268731" /xcortree=140 /SigmaFactorBS="aaacacatcagctgacgattaaaattttccaagagaatgccg AGATtggtacaatggcagttCAGGAAGTGATCCAGAAAATggagcgatccatcctgtc t" /listShort="S358, yhgE" /GFF_Attribute="listLong" promotor_-10 1090094..1090113 /Source="Nicolas_upshift_promotors" /id="U818" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.731268731268731" /psig="0.731268731268731" /xcortree=140 /SigmaFactorBS="aaacacatcagctgacgattaaaattttccaagagaatgccg AGATtggtacaatggcagttCAGGAAGTGATCCAGAAAATggagcgatccatcctgtc t" /listShort="S358, yhgE" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 1090331..1090400 /Source="Nicolas_S_feature" /locus_tag="new_1090331_1090400" /HighExp="G135, G150, G180, BI, Salt, Etha, Cold, Heat, Oxctl, LBGexp" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigB, SigA" /TUshortPSig="0.731, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S358" CDS 1090401..1092728 /gene="yhgE" /locus_tag="BSU_10160" /old_locus_tag="BSU10160" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15576783; Product type f: factor" /codon_start=1 /transl_table=11 /product="putative methyl-accepting protein" /protein_id="NP_388897.1" /db_xref="EnsemblGenomes-Gn:BSU10160" /db_xref="EnsemblGenomes-Tr:CAB12856" /db_xref="GOA:P32399" /db_xref="InterPro:IPR017500" /db_xref="InterPro:IPR017501" /db_xref="InterPro:IPR020846" /db_xref="InterPro:IPR023908" /db_xref="SubtiList:BG10433" /db_xref="UniProtKB/Swiss-Prot:P32399" /translation="MNTIRSQWKDIVTSKKLLIPIIAILFVPLIYSGVFLKAYWDPYG TVDQLPVVVVNQDKGATYEGEKLQIGDDLVKELKDNNNFDWHFSNDLDQSLKDLLNQK YYLVVEIPEDFSKNASTVLDKNPKKLDLKYHTNAGSNYVGATIGEKAIDKLKASVSKE VTEQYTKVIFDNFKDIAKGLSDASSGAKKIDDGTKDAKNGSAQLKENLAKLKESTATI SDKTAQLADGAAQVTSGIQSLDSSLGKFQDSSNQIYDKSSQLAAGSGELTSKMNELLA GLQNVQKGTPNLTNGLDQLNSKVQEGSEKAAKAEKIINALDLTKLETAVNNLEKSETA MKEFKKQLTDFENSLKNRDQAFKNVINSSDFLTAEQKSQLINSVEKKLPQVDAPDFDQ ILSQLPTADQLPDIATIKSSLEDVKAQVAQVKAMPEATSKLYNGAKTIQDAIDRLTEG ADKIYNGSQKLTDGQTKLTAGIGEYNKQFAKAKAGSEQLVTGSSQVSGGLFKLLDGSK QVQSGSSKLADGSASLDTGLGKLLDGTGELSSKLKDAADQTGDIDADDQTYGMFADPV KTKDDAIHSVPNYGTGLTPYILSMGLYVGGIMLTVVFPLKEASGRPRNGFEWFFSKFN VMMLVGIIQSLIVATVLLLGIGLEVESTWRFYVFTIITSLAFLAIIQFLATTMGNPGR FIAVIILVLQLGASGGTFPLELLPNFYQVIHGALPMTYSINGFRAVISNGDFGYMWQM AGVLIGIALVMIALSITYFTMLSRKEETSEEQPAS*" gene 1090401..1092728 /gene="yhgE" /locus_tag="BSU_10160" /old_locus_tag="BSU10160" downshifts 1092710 /Source="Nicolas_upshifts" /id="D552" /incds=0 /nref=65 /ntot=211 /MaxReadThrough="0.57274" /MaxDrop="5.58483" /score="-4.79013797" /energy="-7.3" /TU="NA" /idTUdmin="U817" /TUdmin=0 /isTUend="TRUE" CDS complement(1092770..1093747) /gene="fabHB" /locus_tag="BSU_10170" /old_locus_tag="BSU10170" /EC_number="2.3.1.180" /EC_number="2.3.1.38" /function="16.8: Protect" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:10629181, 21383089, 21542858" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10629181, 21383089, 21542858; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="beta-ketoacyl-acyl carrier protein synthase III 2" /protein_id="NP_388898.1" /db_xref="EnsemblGenomes-Gn:BSU10170" /db_xref="EnsemblGenomes-Tr:CAB12857" /db_xref="GOA:O07600" /db_xref="InterPro:IPR004655" /db_xref="InterPro:IPR013747" /db_xref="InterPro:IPR013751" /db_xref="InterPro:IPR016039" /db_xref="SubtiList:BG13048" /db_xref="UniProtKB/Swiss-Prot:O07600" /translation="MSKAKITAIGTYAPSRRLTNADLEKIVDTSDEWIVQRTGMRERR IADEHQFTSDLCIEAVKNLKSRYKGTLDDVDMILVATTTSDYAFPSTACRVQEYFGWE STGALDINATCAGLTYGLHLANGLITSGLHQKILVIAGETLSKVTDYTDRTTCVLFGD AAGALLVERDEETPGFLASVQGTSGNGGDILYRAGLRNEINGVQLVGSGKMVQNGREV YKWAARTVPGEFERLLHKAGLSSDDLDWFVPHSANLRMIESICEKTPFPIEKTLTSVE HYGNTSSVSIVLALDLAVKAGKLKKDQIVLLFGFGGGLTYTGLLIKWGM*" gene complement(1092770..1093747) /gene="fabHB" /locus_tag="BSU_10170" /old_locus_tag="BSU10170" downshifts complement(1092783) /Source="Nicolas_upshifts" /id="D553" /incds=0 /nref=21 /ntot=217 /MaxReadThrough="1.99012" /MaxDrop="7.90433" /score="-9.17544275" /energy="-7.3" /TU="NA" /idTUdmin="U819" /TUdmin="-19" /isTUend="TRUE" promotor_-10 complement(1093761..1093780) /Source="Nicolas_upshift_promotors" /id="U819" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.466533466533467" /psig="0.999000999001" /xcortree=2184 /SigmaFactorBS="atctacacttctctttttttgtaaaaaaaccttctttttAGT ACCAgatactaatatctAGTGTTATAATCTGACCATAaggagtgattcatatgtcaaa a" /listShort="fabHB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1093779) /Source="Nicolas_upshifts" /id="U819" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.466533466533467" /psig="0.999000999001" /xcortree=2184 /SigmaFactorBS="atctacacttctctttttttgtaaaaaaaccttctttttAGT ACCAgatactaatatctAGTGTTATAATCTGACCATAaggagtgattcatatgtcaaa a" /listShort="fabHB" /GFF_Attribute="listLong" promotor_-35 complement(1093794..1093800) /Source="Nicolas_upshift_promotors" /id="U819" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.466533466533467" /psig="0.999000999001" /xcortree=2184 /SigmaFactorBS="atctacacttctctttttttgtaaaaaaaccttctttttAGT ACCAgatactaatatctAGTGTTATAATCTGACCATAaggagtgattcatatgtcaaa a" /listShort="fabHB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1093806..1093814 /Source="Nicolas_upshift_promotors" /id="U820" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=3194 /SigmaFactorBS="tataacactagatattagtatctggtactaaaaaGAAGGTTT TtttacaaaaaAAGAGAAGTGTAGATAGGAatctatgaaaaagaaaaaggaggctgaa a" /listShort="yhfC, S360, yhfE, yhfF" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1093825..1093843 /Source="Nicolas_upshift_promotors" /id="U820" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=3194 /SigmaFactorBS="tataacactagatattagtatctggtactaaaaaGAAGGTTT TtttacaaaaaAAGAGAAGTGTAGATAGGAatctatgaaaaagaaaaaggaggctgaa a" /listShort="yhfC, S360, yhfE, yhfF" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1093832 /Source="Nicolas_upshifts" /id="U820" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=3194 /SigmaFactorBS="tataacactagatattagtatctggtactaaaaaGAAGGTTT TtttacaaaaaAAGAGAAGTGTAGATAGGAatctatgaaaaagaaaaaggaggctgaa a" /listShort="yhfC, S360, yhfE, yhfF" /GFF_Attribute="listLong" CDS 1093874..1094650 /gene="yhfC" /locus_tag="BSU_10180" /old_locus_tag="BSU10180" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative integral membrane protein" /protein_id="NP_388899.1" /db_xref="EnsemblGenomes-Gn:BSU10180" /db_xref="EnsemblGenomes-Tr:CAB12858" /db_xref="GOA:O07601" /db_xref="InterPro:IPR011397" /db_xref="SubtiList:BG13049" /db_xref="UniProtKB/Swiss-Prot:O07601" /translation="MVSQEAVVFLALSGAIAFLLPIGLIVWFKRKYGASLKVFFIGAL TFFVFAQLLEGGVHVYVLQVNEMTKEAMQHPLWYGIYGCLMAGIFEECGRYLMMRFFM KRHHTWADGLAFGAGHGGLEAILITGLSSISLIVYAFAINSGTFEQLLVNGDVKQALL PIQEQLLHTPSYEWMLGGIERISAIAVQIGLSLLVLYAVKNRRPLFLLYSILLHALFN VPAVLYQRGIIEHAAAVEIIVALIAALSVYWIVKAKRVFQ*" gene 1093874..1094650 /gene="yhfC" /locus_tag="BSU_10180" /old_locus_tag="BSU10180" S_feature complement(1094366..1094987) /Source="Nicolas_S_feature" /locus_tag="new_1094366_1094987_c" /HighExp="B36, BT, B60, Pyr, S8, G/S, G135, Mal, M/G, Glucon" /AntisenseName="yhfC" /AntisenseCor="-0.12937903461570099" /AntisenseRegPval="-1.5" /CDS_PredictionProba="0.51248700000000003" /TUshortSig="SigK" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S359" S_feature 1094651..1095022 /Source="Nicolas_S_feature" /locus_tag="new_1094651_1095022" /HighExp="Lbstat, S2, M0t90, M40t90, HiOs, SMMPr, T-2.40H, Etha, Lbtran, Cold" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.48518699999999998" /TUshortSig="SigH" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S360" promotor_-10 complement(1094965..1094984) /Source="Nicolas_upshift_promotors" /id="U821" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1428 /SigmaFactorBS="tattttctacttaaaatatactcttttcccgagggacccGTC CAATCTTttcctatcaatctCTCATATGCTGTAGAGAGCAtgggaagaggagggattt c" /listShort="S359" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1094986) /Source="Nicolas_upshifts" /id="U821" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1428 /SigmaFactorBS="tattttctacttaaaatatactcttttcccgagggacccGTC CAATCTTttcctatcaatctCTCATATGCTGTAGAGAGCAtgggaagaggagggattt c" /listShort="S359" /GFF_Attribute="listLong" promotor_-35 complement(1094998..1095007) /Source="Nicolas_upshift_promotors" /id="U821" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1428 /SigmaFactorBS="tattttctacttaaaatatactcttttcccgagggacccGTC CAATCTTttcctatcaatctCTCATATGCTGTAGAGAGCAtgggaagaggagggattt c" /listShort="S359" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1095000..1095007 /Source="Nicolas_upshift_promotors" /id="U822" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.78921078921079" /psig="0.96003996003996" /xcortree=2233 /SigmaFactorBS="atgctctctacagcatatgagagattgataggaaaaGATTGG ACgggtccctcgggaaAAGAGTATATTTTAAGTAGAaaataaaaggaggaatgcccta t" /listShort="yhfE, yhfF" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1095022..1095041 /Source="Nicolas_upshift_promotors" /id="U822" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.78921078921079" /psig="0.96003996003996" /xcortree=2233 /SigmaFactorBS="atgctctctacagcatatgagagattgataggaaaaGATTGG ACgggtccctcgggaaAAGAGTATATTTTAAGTAGAaaataaaaggaggaatgcccta t" /listShort="yhfE, yhfF" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1095024 /Source="Nicolas_upshifts" /id="U822" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.78921078921079" /psig="0.96003996003996" /xcortree=2233 /SigmaFactorBS="atgctctctacagcatatgagagattgataggaaaaGATTGG ACgggtccctcgggaaAAGAGTATATTTTAAGTAGAaaataaaaggaggaatgcccta t" /listShort="yhfE, yhfF" /GFF_Attribute="listLong" CDS 1095063..1096103 /gene="yhfE" /locus_tag="BSU_10200" /old_locus_tag="BSU10200" /EC_number="3.4.11.-" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15713475, 15743956; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative aminopeptidase" /protein_id="NP_388901.1" /db_xref="EnsemblGenomes-Gn:BSU10200" /db_xref="EnsemblGenomes-Tr:CAB12860" /db_xref="GOA:O07603" /db_xref="InterPro:IPR008007" /db_xref="InterPro:IPR023367" /db_xref="SubtiList:BG13051" /db_xref="UniProtKB/Swiss-Prot:O07603" /translation="MTSVRKTMELIKELVSIPSPTGNTYEVINYIESLLKEWKVETVR NHKGGLIATLPGRDTSRHRMLTAHVDTLGAMVKEIKADGRLKIDLIGGFRYNSIEGEY CQIETASGKMYTGTILMHQTSVHVYKDAGKAERNQENMEIRLDEPVHCRKDTEELGIG VGDFVSFDPRVEITSSGFIKSRHLDDKASVALLLRLIHEIQTEDIELPYTTHFLISNN EEIGYGGNSNIPPETVEYLAVDMGAIGDGQATDEYSVSICVKDASGPYHYQLRKHLVQ LAEKHHIDYKLDIYPYYGSDASAAIKSGHDIVHGLIGPGIDASHAFERTHKSSLRHTA KLLYYYVQSPMV*" gene 1095063..1096103 /gene="yhfE" /locus_tag="BSU_10200" /old_locus_tag="BSU10200" CDS 1096116..1096523 /gene="yhfF" /locus_tag="BSU_10210" /old_locus_tag="BSU10210" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 11157739, 14517985; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative RNA-binding PUA-containing enzyme" /protein_id="NP_388902.1" /db_xref="EnsemblGenomes-Gn:BSU10210" /db_xref="EnsemblGenomes-Tr:CAB12861" /db_xref="InterPro:IPR007374" /db_xref="InterPro:IPR009326" /db_xref="InterPro:IPR015947" /db_xref="SubtiList:BG13052" /db_xref="UniProtKB/Swiss-Prot:O07604" /translation="MKIYKLKSTFGWEGDDGLGEQLIQQILAGEKSATCAPKSLYSKD ELRDVYQTAGQLVTVYDKHDNPRCNIKVTDVFETTFGAPDMRLVKGEGNGDRIEEFQE DHRMAWAELIKSGELELNEDTVLITELFVLVKD*" gene 1096116..1096523 /gene="yhfF" /locus_tag="BSU_10210" /old_locus_tag="BSU10210" downshifts 1096494 /Source="Nicolas_upshifts" /id="D554" /incds=0 /nref=24 /ntot=228 /MaxReadThrough="0.87656" /MaxDrop="5.21108" /score="22.0862441" /energy="-20.3" /TU="U822" /idTUdmin="U822" /TUdmin="-23" /isTUend="FALSE" CDS complement(1096560..1097849) /gene="gltT" /locus_tag="BSU_10220" /old_locus_tag="BSU10220" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:8634258, 10588697, 11148213, 15849754, 16850406, 17673229, 25344233" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8634258, 10588697, 11148213, 15849754, 16850406, 17673229, 25344233; Product type t: transporter" /codon_start=1 /transl_table=11 /product="proton/sodium-glutamate (aspartate) symport permease" /protein_id="NP_388903.1" /db_xref="EnsemblGenomes-Gn:BSU10220" /db_xref="EnsemblGenomes-Tr:CAB12862" /db_xref="GOA:O07605" /db_xref="InterPro:IPR001991" /db_xref="InterPro:IPR018107" /db_xref="InterPro:IPR033380" /db_xref="InterPro:IPR036458" /db_xref="SubtiList:BG12595" /db_xref="UniProtKB/Swiss-Prot:O07605" /translation="MKRIKFGLATQIFVGLILGVIVGVIWYGNPALPTYLQPIGDLFL RLIKMIVIPIVVSSLIIGVAGAGNGKQVGKLGFRTILYFEIITTFAIILGLALANIFH PGTGVNIHEAQKSDISQYVETEKEQSNKSVAETFLHIVPTNFFQSLVEGDLLAIICFT VLFALGISAIGERGKPVLAFFEGVSHAMFHVVNLVMKVAPFGVFALIGVTVSKFGLGS LISLGKLVGLVYVALAFFLIVIFGIVAKIAGISIFKFLAYMKDEILLAFSTSSSETVL PRIMEKMEKIGCPKGIVSFVIPIGYTFNLDGSVLYQSIAALFLAQVYGIDLTIWHQIT LVLVLMVTSKGMAAVPGTSFVVLLATLGTIGVPAEGLAFIAGVDRIMDMARTVVNLTG NALAAVVMSKWEGMFNPAKAETVMSQSKTEQNATISG*" gene complement(1096560..1097849) /gene="gltT" /locus_tag="BSU_10220" /old_locus_tag="BSU10220" downshifts complement(1096590) /Source="Nicolas_upshifts" /id="D555" /incds=0 /nref=226 /ntot=280 /MaxReadThrough="2.99263" /MaxDrop="7.79183" /score="48.7726082" /energy="-21.9" /TU="U823" /idTUdmin="U824" /TUdmin=3 /isTUend="TRUE" S_feature complement(1097850..1097950) /Source="Nicolas_S_feature" /locus_tag="new_1097850_1097950_c" /HighExp="C90, LoTm, LBGexp, Cold, UNK1, BC, dia5, Lbexp, S1, T3.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="1, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S361" promotor_-10 complement(1097949..1097968) /Source="Nicolas_upshift_promotors" /id="U823" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.556443556443556" /psig=1 /xcortree=2240 /SigmaFactorBS="tctggtgattatcataatgtcATTGAATattctttattttcg AAATATAATTTACTATAGACgaattgatttcttatctattataatttgatctaatagt g" /listShort="S361, gltT" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1097950) /Source="Nicolas_upshifts" /id="U823" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.556443556443556" /psig=1 /xcortree=2240 /SigmaFactorBS="tctggtgattatcataatgtcATTGAATattctttattttcg AAATATAATTTACTATAGACgaattgatttcttatctattataatttgatctaatagt g" /listShort="S361, gltT" /GFF_Attribute="listLong" S_feature complement(1097952..1098088) /Source="Nicolas_S_feature" /locus_tag="new_1097952_1098088_c" /HighExp="M9-stat, T3.30H, T3.0H, T4.0H, T2.30H, T5.0H, Cold, T2.0H, S0, B60" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S362" promotor_-35 complement(1097983..1097989) /Source="Nicolas_upshift_promotors" /id="U823" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.556443556443556" /psig=1 /xcortree=2240 /SigmaFactorBS="tctggtgattatcataatgtcATTGAATattctttattttcg AAATATAATTTACTATAGACgaattgatttcttatctattataatttgatctaatagt g" /listShort="S361, gltT" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(1098120..1098260) /gene="yhfH" /locus_tag="BSU_10230" /old_locus_tag="BSU10230" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_388904.1" /db_xref="EnsemblGenomes-Gn:BSU10230" /db_xref="EnsemblGenomes-Tr:CAB12863" /db_xref="InterPro:IPR025432" /db_xref="SubtiList:BG13053" /db_xref="UniProtKB/Swiss-Prot:O07606" /translation="MVMLGKITEFFRNLPSKKCAECGKKIEEQHECYGNICNDCIKVN DL*" gene complement(1098120..1098260) /gene="yhfH" /locus_tag="BSU_10230" /old_locus_tag="BSU10230" downshifts complement(1098133) /Source="Nicolas_upshifts" /id="D556" /incds=0 /nref=3 /ntot=16 /MaxReadThrough="5.70702" /MaxDrop="4.73949" /score="28.7665297" /energy="-13.6" /TU="U824" /idTUdmin="U824" /TUdmin="-1540" /isTUend="FALSE" promotor_-10 complement(1098279..1098298) /Source="Nicolas_upshift_promotors" /id="U824" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.454545454545455" /psig=1 /xcortree=433 /SigmaFactorBS="tcttgaaaaaagcatgttttaaacattgtatcaaaacagtTA TTGATTtttgtaatctgtTATATTACAATGAAATCACTacaaaggggaaagagggatt g" /listShort="yhfH, S362, S361, gltT" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1098298) /Source="Nicolas_upshifts" /id="U824" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.454545454545455" /psig=1 /xcortree=433 /SigmaFactorBS="tcttgaaaaaagcatgttttaaacattgtatcaaaacagtTA TTGATTtttgtaatctgtTATATTACAATGAAATCACTacaaaggggaaagagggatt g" /listShort="yhfH, S362, S361, gltT" /GFF_Attribute="listLong" promotor_-35 complement(1098311..1098318) /Source="Nicolas_upshift_promotors" /id="U824" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.454545454545455" /psig=1 /xcortree=433 /SigmaFactorBS="tcttgaaaaaagcatgttttaaacattgtatcaaaacagtTA TTGATTtttgtaatctgtTATATTACAATGAAATCACTacaaaggggaaagagggatt g" /listShort="yhfH, S362, S361, gltT" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1098342..1098348 /Source="Nicolas_upshift_promotors" /id="U825" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.621378621378621" /psig="0.99100899100899" /xcortree=1999 /SigmaFactorBS="tacaaaaatcaataactgttttgatacaatgtttaaaACATG CTtttttcaagaaaaATGGGTATATTGAAGGAGGAccaatttttttgaaaagatagga g" /listShort="yhfI, yhfJ, yhfK" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1098362..1098381 /Source="Nicolas_upshift_promotors" /id="U825" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.621378621378621" /psig="0.99100899100899" /xcortree=1999 /SigmaFactorBS="tacaaaaatcaataactgttttgatacaatgtttaaaACATG CTtttttcaagaaaaATGGGTATATTGAAGGAGGAccaatttttttgaaaagatagga g" /listShort="yhfI, yhfJ, yhfK" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1098365 /Source="Nicolas_upshifts" /id="U825" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.621378621378621" /psig="0.99100899100899" /xcortree=1999 /SigmaFactorBS="tacaaaaatcaataactgttttgatacaatgtttaaaACATG CTtttttcaagaaaaATGGGTATATTGAAGGAGGAccaatttttttgaaaagatagga g" /listShort="yhfI, yhfJ, yhfK" /GFF_Attribute="listLong" CDS 1098412..1099146 /gene="yhfI" /locus_tag="BSU_10240" /old_locus_tag="BSU10240" /function="16.8: Protect" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative metal-dependent hydrolase" /protein_id="NP_388905.1" /db_xref="EnsemblGenomes-Gn:BSU10240" /db_xref="EnsemblGenomes-Tr:CAB12864" /db_xref="GOA:O07607" /db_xref="InterPro:IPR001279" /db_xref="InterPro:IPR036866" /db_xref="SubtiList:BG13054" /db_xref="UniProtKB/Swiss-Prot:O07607" /translation="MKVTVIGCYGGFPAANEATSGYLFQSGDYSLLVDCGSAVLSKLF GYVPAEKLDAVVLSHYHHDHIADIGPLQFAKQVGSFLGKGEHTLPIYGHDADIEQFQK LTYKTHTKGIAYQPDQPLTAGPFTITFLKTIHPVTCYAMRITDGSHTVVYTADSSYQD SFIPFSKDADLLISECNFYADQDGTSAGHMNSLEAGRIAKEAGAGELLLTHLPHFGVH DNLRKEAKTVFNGEVNIAKSGFVWEG*" gene 1098412..1099146 /gene="yhfI" /locus_tag="BSU_10240" /old_locus_tag="BSU10240" CDS 1099159..1100154 /gene="lplJ" /locus_tag="BSU_10250" /old_locus_tag="BSU10250" /EC_number="6.3.1.20" /experiment="publication(s) with functional evidences, PMID:21338420, 21338421" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 21338420, 21338421; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="lipoate-protein ligase" /protein_id="NP_388906.1" /db_xref="EnsemblGenomes-Gn:BSU10250" /db_xref="EnsemblGenomes-Tr:CAB12865" /db_xref="GOA:O07608" /db_xref="InterPro:IPR004143" /db_xref="InterPro:IPR004562" /db_xref="InterPro:IPR019491" /db_xref="SubtiList:BG13055" /db_xref="UniProtKB/Swiss-Prot:O07608" /translation="MLFIDNQNINDPRINLAIEEYCVKHLDPEQQYLLFYVNQPSIII GKNQNTIEEINTKYVEENGIIVVRRLSGGGAVYHDLGNLNFSFITKDDGDSFHNFKKF TEPVIQALHQLGVEAELSGRNDIVVDGRKISGNAQFATKGRIFSHGTLMFDSAIDHVV SALKVKKDKIESKGIKSIRSRVANISEFLDDKMTTEEFRSHLLRHIFNTNDVGNVPEY KLTEKDWETIHQISKERYQNWDWNYGRSPKFNLNHSKRYPVGSIDLHLEVKKGKIEDC KIFGDFFGVGDVSEIENLLVGKQYERSVIADVLEGVNLKHYFGNITKEDFLDLIY*" gene 1099159..1100154 /gene="lplJ" /locus_tag="BSU_10250" /old_locus_tag="BSU10250" CDS 1100219..1100863 /gene="yhfK" /locus_tag="BSU_10260" /old_locus_tag="BSU10260" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 11790741; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative NAD-binding epimerase / hydratase" /protein_id="NP_388907.1" /db_xref="EnsemblGenomes-Gn:BSU10260" /db_xref="EnsemblGenomes-Tr:CAB12866" /db_xref="GOA:O07609" /db_xref="InterPro:IPR016040" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG13056" /db_xref="UniProtKB/Swiss-Prot:O07609" /translation="MKVFLIGANGQIGQRLVSLFQDNPDHSIRAMVRKEEQKASLEAA GAEAVLANLEGSPEEIAAAAKGCDAIIFTAGSGGSTGYDKTLLVDLDGAAKAIEAAAI AGIKRFIMVSALQAHNRENWNEALKPYYVAKHYADKILEASGLTYTIIRPGGLRNEPG TGTVSAAKDLERGFISRDDVAKTVIASLDEKNTENRAFDLTEGDTPIAEALKKL*" gene 1100219..1100863 /gene="yhfK" /locus_tag="BSU_10260" /old_locus_tag="BSU10260" downshifts 1100851 /Source="Nicolas_upshifts" /id="D557" /incds=0 /nref=239 /ntot=258 /MaxReadThrough="0.56809" /MaxDrop="6.84076" /score="18.2092404" /energy="-10" /TU="NA" /idTUdmin="U825" /TUdmin=0 /isTUend="TRUE" promotor_-35 1100891..1100894 /Source="Nicolas_upshift_promotors" /id="U826" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.619380619380619" /psig=1 /xcortree=374 /SigmaFactorBS="aactatgacagtactgacactcagggctttttgctCTTGagt gtttttttctgTTTCTCTATAATGGAGAAGAaagcttggcttcaataatgaatgacta t" /listShort="lcfB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1100909..1100928 /Source="Nicolas_upshift_promotors" /id="U826" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.619380619380619" /psig=1 /xcortree=374 /SigmaFactorBS="aactatgacagtactgacactcagggctttttgctCTTGagt gtttttttctgTTTCTCTATAATGGAGAAGAaagcttggcttcaataatgaatgacta t" /listShort="lcfB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1100916 /Source="Nicolas_upshifts" /id="U826" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.619380619380619" /psig=1 /xcortree=374 /SigmaFactorBS="aactatgacagtactgacactcagggctttttgctCTTGagt gtttttttctgTTTCTCTATAATGGAGAAGAaagcttggcttcaataatgaatgacta t" /listShort="lcfB" /GFF_Attribute="listLong" CDS 1100980..1102521 /gene="lcfB" /locus_tag="BSU_10270" /old_locus_tag="BSU10270" /EC_number="6.2.1.3" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:17189250, 21398533" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 17189250, 21398533; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="long-chain fatty-acid-CoA ligase (degradative)" /protein_id="NP_388908.2" /db_xref="EnsemblGenomes-Gn:BSU10270" /db_xref="EnsemblGenomes-Tr:CAB12867" /db_xref="GOA:O07610" /db_xref="InterPro:IPR000873" /db_xref="InterPro:IPR020459" /db_xref="InterPro:IPR020845" /db_xref="InterPro:IPR025110" /db_xref="SubtiList:BG13057" /db_xref="UniProtKB/Swiss-Prot:O07610" /translation="MNLVSKLEETASEKPDSIACRFKDHMMTYQELNEYIQRFADGLQ EAGMEKGDHLALLLGNSPDFIIAFFGALKAGIVVVPINPLYTPTEIGYMLTNGDVKAI VGVSQLLPLYESMHESLPKVELVILCQTGEAEPEAADPEVRMKMTTFAKILRPTSAAK QNQEPVPDDTAVILYTSGTTGKPKGAMLTHQNLYSNANDVAGYLGMDERDNVVCALPM FHVFCLTVCMNAPLMSGATVLIEPQFSPASVFKLVKQQQATIFAGVPTMYNYLFQHEN GKKDDFSSIRLCISGGASMPVALLTAFEEKFGVTILEGYGLSEASPVTCFNPFDRGRK PGSIGTSILHVENKVVDPLGRELPAHQVGELIVKGPNVMKGYYKMPMETEHALKDGWL YTGDLARRDEDGYFYIVDRKKDMIIVGGYNVYPREVEEVLYSHPDVKEAVVIGVPDPQ SGEAVKGYVVPKRSGVTEEDIMQHCEKHLAKYKRPAAITFLDDIPKNATGKMLRRALR DILPQ*" gene 1100980..1102521 /gene="lcfB" /locus_tag="BSU_10270" /old_locus_tag="BSU10270" downshifts 1102501 /Source="Nicolas_upshifts" /id="D558" /incds=0 /nref=5 /ntot=108 /MaxReadThrough="2.74134" /MaxDrop="3.72638" /score="15.3712924" /energy="-10.4" /TU="NA" /idTUdmin="U826" /TUdmin=0 /isTUend="TRUE" CDS complement(1102560..1102955) /gene="yhfM" /locus_tag="BSU_10280" /old_locus_tag="BSU10280" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative membrane protein" /protein_id="NP_388909.1" /db_xref="EnsemblGenomes-Gn:BSU10280" /db_xref="EnsemblGenomes-Tr:CAB12868" /db_xref="SubtiList:BG13058" /db_xref="UniProtKB/Swiss-Prot:O07611" /translation="MKKIVAAIVVIGLVFIAFFYLYSRSGDVYQSVDADLITLSSSGQ EDIEIEKRQHVKDMLDIMNQGKQVKTEKTSAPDYEGTIKFHKDRYDSFRLWIDGSQQA VFLKDGTYYKLSKNDTKALLNIIKKEAKD*" gene complement(1102560..1102955) /gene="yhfM" /locus_tag="BSU_10280" /old_locus_tag="BSU10280" downshifts complement(1102577) /Source="Nicolas_upshifts" /id="D559" /incds=0 /nref=46 /ntot=89 /MaxReadThrough="0.75539" /MaxDrop="6.88759" /score="17.4775611" /energy="-10.4" /TU="NA" /idTUdmin="U827" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(1102975..1102986) /Source="Nicolas_upshift_promotors" /id="U827" /multdbtbs="SigF" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=1141 /SigmaFactorBS="caagctgtgttccgcacttttccacccttttaAGCATGGaaa ccccgatcgctGGGAAAACTAACaatgtttggagtgatgcaaatgaaaaaaatagtgg c" /listShort="yhfM" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1102979) /Source="Nicolas_upshifts" /id="U827" /multdbtbs="SigF" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=1141 /SigmaFactorBS="caagctgtgttccgcacttttccacccttttaAGCATGGaaa ccccgatcgctGGGAAAACTAACaatgtttggagtgatgcaaatgaaaaaaatagtgg c" /listShort="yhfM" /GFF_Attribute="listLong" promotor_-35 complement(1103001..1103007) /Source="Nicolas_upshift_promotors" /id="U827" /multdbtbs="SigF" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=1141 /SigmaFactorBS="caagctgtgttccgcacttttccacccttttaAGCATGGaaa ccccgatcgctGGGAAAACTAACaatgtttggagtgatgcaaatgaaaaaaatagtgg c" /listShort="yhfM" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1103040..1103043 /Source="Nicolas_upshift_promotors" /id="U828" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.635364635364635" /psig="0.785214785214785" /xcortree=1404 /SigmaFactorBS="atcggggtttccatgcttaaaagggtggaaaagtgcggaaca cagcttgGTTCtaagaatttgaattTATGATTACAATAGAAGTAAcgggttgatgtga g" /listShort="yhfN" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 1103051 /Source="Nicolas_upshifts" /id="U828" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.635364635364635" /psig="0.785214785214785" /xcortree=1404 /SigmaFactorBS="atcggggtttccatgcttaaaagggtggaaaagtgcggaaca cagcttgGTTCtaagaatttgaattTATGATTACAATAGAAGTAAcgggttgatgtga g" /listShort="yhfN" /GFF_Attribute="listLong" promotor_-10 1103058..1103077 /Source="Nicolas_upshift_promotors" /id="U828" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.635364635364635" /psig="0.785214785214785" /xcortree=1404 /SigmaFactorBS="atcggggtttccatgcttaaaagggtggaaaagtgcggaaca cagcttgGTTCtaagaatttgaattTATGATTACAATAGAAGTAAcgggttgatgtga g" /listShort="yhfN" /GFF_Attribute="listLong" /label="promotor_-10" CDS 1103104..1104384 /gene="yhfN" /locus_tag="BSU_10290" /old_locus_tag="BSU10290" /EC_number="3.4.24.84" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 9015299; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative membrane metalloprotease" /protein_id="NP_388910.1" /db_xref="EnsemblGenomes-Gn:BSU10290" /db_xref="EnsemblGenomes-Tr:CAB12869" /db_xref="GOA:P40769" /db_xref="InterPro:IPR001915" /db_xref="InterPro:IPR027057" /db_xref="InterPro:IPR032456" /db_xref="SubtiList:BG11029" /db_xref="UniProtKB/Swiss-Prot:P40769" /translation="MRKWIAAAGLAYVLYGLFFYWYFFLSGDSAIPEAVKGTQADPAS FMKPSELAVAEQYSNVKNFLFFIGVPLDWFLFFVLLVSGVSKKIKKWIEAAVPFRFLQ TVGFVFVLSLITTLVTLPLDWIGYQVSLDYNISTQTTASWAKDQVISFWISFPIFTLC VLVFYWLIKRHEKKWWLYAWLLTVPFSLFLFFIQPVIIDPLYNDFYPLKNKELESKIL ELADEANIPADHVYEVNMSEKTNALNAYVTGIGANKRIVLWDTTLNKLDDSEILFIMG HEMGHYVMKHVYIGLAGYLLVSLAGFYVIDKLYKRTVRLTRSMFHLEGRHDLAALPLL LLLFSVLSFAVTPFSNAVSRYQENKADQYGIELTENREAAVKTFQDLAVTGLSQVDPP VLVKIFRGSHPSIMERIQHAEKEENAPEHQDADK*" gene 1103104..1104384 /gene="yhfN" /locus_tag="BSU_10290" /old_locus_tag="BSU10290" promotor_-10 complement(1103531..1103550) /Source="Nicolas_upshift_promotors" /id="U829" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.574425574425574" /psig="0.974025974025974" /xcortree=1821 /SigmaFactorBS="tcagccaataaaaaacgagaacgcaaagcgtaaaGATTGGaa agctgatccaaaaGCTGATAACCTGATCCTTAGcccagctggccgttgtctgtgtgga a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1103545) /Source="Nicolas_upshifts" /id="U829" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.574425574425574" /psig="0.974025974025974" /xcortree=1821 /SigmaFactorBS="tcagccaataaaaaacgagaacgcaaagcgtaaaGATTGGaa agctgatccaaaaGCTGATAACCTGATCCTTAGcccagctggccgttgtctgtgtgga a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(1103566..1103571) /Source="Nicolas_upshift_promotors" /id="U829" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.574425574425574" /psig="0.974025974025974" /xcortree=1821 /SigmaFactorBS="tcagccaataaaaaacgagaacgcaaagcgtaaaGATTGGaa agctgatccaaaaGCTGATAACCTGATCCTTAGcccagctggccgttgtctgtgtgga a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 1104371 /Source="Nicolas_upshifts" /id="D560" /incds=0 /nref=2 /ntot=57 /MaxReadThrough="3.82026" /MaxDrop="3.6342" /score="6.45541384" /energy="-12.7" /TU="U828" /idTUdmin="U828" /TUdmin="-132" /isTUend="FALSE" downshifts complement(1104421) /Source="Nicolas_upshifts" /id="D561" /incds=0 /nref=129 /ntot=219 /MaxReadThrough="-0.11848" /MaxDrop="9.02627" /score="-6.76069514" /energy="-7.8" /TU="NA" /idTUdmin="U830" /TUdmin=4 /isTUend="TRUE" CDS complement(1104423..1105568) /gene="aprE" /locus_tag="BSU_10300" /old_locus_tag="BSU10300" /EC_number="3.4.21.62" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:3108260, 9811547, 12950930, 14688235, 15205417, 17666034, 19710937, 26728191" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 3108260, 9811547, 12950930, 14688235, 15205417, 17666034, 19710937, 26728191; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="serine alkaline protease (Ca(2+)-dependent subtilisin E)" /protein_id="NP_388911.2" /db_xref="EnsemblGenomes-Gn:BSU10300" /db_xref="EnsemblGenomes-Tr:CAB12870" /db_xref="GOA:P04189" /db_xref="InterPro:IPR000209" /db_xref="InterPro:IPR009020" /db_xref="InterPro:IPR010259" /db_xref="InterPro:IPR015500" /db_xref="InterPro:IPR022398" /db_xref="InterPro:IPR023827" /db_xref="InterPro:IPR023828" /db_xref="InterPro:IPR034202" /db_xref="InterPro:IPR036852" /db_xref="InterPro:IPR037045" /db_xref="PDB:1SCJ" /db_xref="PDB:3WHI" /db_xref="SubtiList:BG10190" /db_xref="UniProtKB/Swiss-Prot:P04189" /translation="MRSKKLWISLLFALTLIFTMAFSNMSAQAAGKSSTEKKYIVGFK QTMSAMSSAKKKDVISEKGGKVQKQFKYVNAAAATLDEKAVKELKKDPSVAYVEEDHI AHEYAQSVPYGISQIKAPALHSQGYTGSNVKVAVIDSGIDSSHPDLNVRGGASFVPSE TNPYQDGSSHGTHVAGTIAALNNSIGVLGVAPSASLYAVKVLDSTGSGQYSWIINGIE WAISNNMDVINMSLGGPTGSTALKTVVDKAVSSGIVVAAAAGNEGSSGSTSTVGYPAK YPSTIAVGAVNSSNQRASFSSAGSELDVMAPGVSIQSTLPGGTYGAYNGTSMATPHVA GAAALILSKHPTWTNAQVRDRLESTATYLGNSFYYGKGLINVQAAAQ*" gene complement(1104423..1105568) /gene="aprE" /locus_tag="BSU_10300" /old_locus_tag="BSU10300" S_feature complement(1105569..1105635) /Source="Nicolas_S_feature" /locus_tag="new_1105569_1105635_c" /HighExp="BC, T5.0H, LoTm, Sw, T4.0H, T3.30H, S1, T3.0H, S2, M9-stat" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.996" /TUlongSig="NA" /TUlongPSig="NA" /label="S363" promotor_-10 complement(1105624..1105643) /Source="Nicolas_upshift_promotors" /id="U830" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.524475524475524" /psig="0.996003996003996" /xcortree=468 /SigmaFactorBS="atacctaaatagagataaaatcatctcaaaaaaatgggTCTA CtaaaatattattccaTCTATTACAATAAATTCACAgaatagtcttttaagtaagtct a" /listShort="S363, aprE" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1105641) /Source="Nicolas_upshifts" /id="U830" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.524475524475524" /psig="0.996003996003996" /xcortree=468 /SigmaFactorBS="atacctaaatagagataaaatcatctcaaaaaaatgggTCTA CtaaaatattattccaTCTATTACAATAAATTCACAgaatagtcttttaagtaagtct a" /listShort="S363, aprE" /GFF_Attribute="listLong" promotor_-35 complement(1105659..1105663) /Source="Nicolas_upshift_promotors" /id="U830" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.524475524475524" /psig="0.996003996003996" /xcortree=468 /SigmaFactorBS="atacctaaatagagataaaatcatctcaaaaaaatgggTCTA CtaaaatattattccaTCTATTACAATAAATTCACAgaatagtcttttaagtaagtct a" /listShort="S363, aprE" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1105948..1105955 /Source="Nicolas_upshift_promotors" /id="U831" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.854145854145854" /psig="0.983016983016983" /xcortree=2175 /SigmaFactorBS="ttcaaagcatgatgataaaagtattctgaaaaataaACTTTA CAgaaaagggatagaaTGAAAAAATTATTGAGAGGGaggaagaaataagatgaacatt c" /listShort="yhfO, yhfP, S364" /listLong="yhfQ" /label="promotor_-35" promotor_-10 1105970..1105989 /Source="Nicolas_upshift_promotors" /id="U831" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.854145854145854" /psig="0.983016983016983" /xcortree=2175 /SigmaFactorBS="ttcaaagcatgatgataaaagtattctgaaaaataaACTTTA CAgaaaagggatagaaTGAAAAAATTATTGAGAGGGaggaagaaataagatgaacatt c" /listShort="yhfO, yhfP, S364" /listLong="yhfQ" /label="promotor_-10" upshifts 1105972 /Source="Nicolas_upshifts" /id="U831" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.854145854145854" /psig="0.983016983016983" /xcortree=2175 /SigmaFactorBS="ttcaaagcatgatgataaaagtattctgaaaaataaACTTTA CAgaaaagggatagaaTGAAAAAATTATTGAGAGGGaggaagaaataagatgaacatt c" /listShort="yhfO, yhfP, S364" /listLong="yhfQ" CDS 1106003..1106452 /gene="yhfO" /locus_tag="BSU_10310" /old_locus_tag="BSU10310" /EC_number="2.3.1.-" /function="16.6: Maintain" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 11717295; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative N-acetyltransferase" /protein_id="NP_388912.1" /db_xref="EnsemblGenomes-Gn:BSU10310" /db_xref="EnsemblGenomes-Tr:CAB12871" /db_xref="GOA:O07614" /db_xref="InterPro:IPR000182" /db_xref="InterPro:IPR016181" /db_xref="SubtiList:BG13059" /db_xref="UniProtKB/Swiss-Prot:O07614" /translation="MNIRQAKTSDAAAIAPLFNQYREFYRQASDLQGAEAFLKARLEN HESVILIAEENGEFIGFTQLYPTFSSVSMKRIYILNDLFVVPHARTKGAGGRLLSAAK DYAGQNGAKCLTLQTEHHNRKARSLYEQNGYEEDTGFVHYCLNVPAK*" gene 1106003..1106452 /gene="yhfO" /locus_tag="BSU_10310" /old_locus_tag="BSU10310" promotor_-35 1106468..1106475 /Source="Nicolas_upshift_promotors" /id="U832" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.95004995004995" /psig=1 /xcortree=2061 /SigmaFactorBS="tgtgccggcgaagtgaaaatggcggcttgatGATTTGGTttt ttgaacgttctTCGGTTACGATATAAATGAAaaggagtgtgccgaatgtcaacgttat t" /listShort="yhfP, S364, yhfQ" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1106490..1106509 /Source="Nicolas_upshift_promotors" /id="U832" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.95004995004995" /psig=1 /xcortree=2061 /SigmaFactorBS="tgtgccggcgaagtgaaaatggcggcttgatGATTTGGTttt ttgaacgttctTCGGTTACGATATAAATGAAaaggagtgtgccgaatgtcaacgttat t" /listShort="yhfP, S364, yhfQ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1106497 /Source="Nicolas_upshifts" /id="U832" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.95004995004995" /psig=1 /xcortree=2061 /SigmaFactorBS="tgtgccggcgaagtgaaaatggcggcttgatGATTTGGTttt ttgaacgttctTCGGTTACGATATAAATGAAaaggagtgtgccgaatgtcaacgttat t" /listShort="yhfP, S364, yhfQ" /GFF_Attribute="listLong" CDS 1106524..1107516 /gene="yhfP" /locus_tag="BSU_10320" /old_locus_tag="BSU10320" /EC_number="1.-.-.-" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 9643546, 12057962; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative oxidoreductase" /protein_id="NP_388913.1" /db_xref="EnsemblGenomes-Gn:BSU10320" /db_xref="EnsemblGenomes-Tr:CAB12872" /db_xref="GOA:O07615" /db_xref="InterPro:IPR011032" /db_xref="InterPro:IPR013149" /db_xref="InterPro:IPR013154" /db_xref="InterPro:IPR014188" /db_xref="InterPro:IPR020843" /db_xref="InterPro:IPR036291" /db_xref="PDB:1TT7" /db_xref="PDB:1Y9E" /db_xref="SubtiList:BG13060" /db_xref="UniProtKB/Swiss-Prot:O07615" /translation="MSTLFQALQAEKNADDVSVHVKTISTEDLPKDGVLIKVAYSGIN YKDGLAGKAGGNIVREYPLILGIDAAGTVVSSNDPRFAEGDEVIATSYELGVSRDGGL SEYASVPGDWLVPLPQNLSLKEAMVYGTAGFTAALSVHRLEQNGLSPEKGSVLVTGAT GGVGGIAVSMLNKRGYDVVASTGNREAADYLKQLGASEVISREDVYDGTLKALSKQQW QGAVDPVGGKQLASLLSKIQYGGSVAVSGLTGGGEVPATVYPFILRGVSLLGIDSVYC PMDVRAAVWERMSSDLKPDQLLTIVDREVSLEETPGALKDILQNRIQGRVIVKL*" gene 1106524..1107516 /gene="yhfP" /locus_tag="BSU_10320" /old_locus_tag="BSU10320" downshifts 1107517 /Source="Nicolas_upshifts" /id="D562" /incds=0 /nref=1 /ntot=37 /MaxReadThrough="4.4421" /MaxDrop="2.9095" /score="14.183693" /energy="-15.3" /TU="U831,U832" /idTUdmin="U831" /TUdmin="-154" /isTUend="FALSE" S_feature 1107562..1107672 /Source="Nicolas_S_feature" /locus_tag="new_1107562_1107672" /HighExp="Etha, dia15, LoTm, Salt, H2O2, LBGexp, Diami, Paraq, dia5, Lbexp" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="1, 0.983" /TUlongSig="NA" /TUlongPSig="NA" /label="S364" promotor_-35 1107650..1107657 /Source="Nicolas_upshift_promotors" /id="U833" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.76023976023976" /psig=1 /xcortree=2107 /SigmaFactorBS="gtaagccgaactttctcttctcattttaaaaataatTGGTGA TAatgattctcattccgTGTTATACTACTCTTGGACAtcttaaccatagaaactacca a" /listShort="yhfQ" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1107673..1107692 /Source="Nicolas_upshift_promotors" /id="U833" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.76023976023976" /psig=1 /xcortree=2107 /SigmaFactorBS="gtaagccgaactttctcttctcattttaaaaataatTGGTGA TAatgattctcattccgTGTTATACTACTCTTGGACAtcttaaccatagaaactacca a" /listShort="yhfQ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1107674 /Source="Nicolas_upshifts" /id="U833" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.76023976023976" /psig=1 /xcortree=2107 /SigmaFactorBS="gtaagccgaactttctcttctcattttaaaaataatTGGTGA TAatgattctcattccgTGTTATACTACTCTTGGACAtcttaaccatagaaactacca a" /listShort="yhfQ" /GFF_Attribute="listLong" CDS 1107733..1108704 /gene="yhfQ" /locus_tag="BSU_10330" /old_locus_tag="BSU10330" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 12354229, 16672620, 20147287; Product type t: transporter" /codon_start=1 /transl_table=11 /product="iron(III) siderophore-binding lipoprotein" /protein_id="NP_388914.2" /db_xref="EnsemblGenomes-Gn:BSU10330" /db_xref="EnsemblGenomes-Tr:CAB12873" /db_xref="GOA:C0SP94" /db_xref="InterPro:IPR002491" /db_xref="SubtiList:BG13061" /db_xref="UniProtKB/Swiss-Prot:C0SP94" /translation="MKKTLIILTVLLLSVLTAACSSSSGNQNSKEHKVAVTHDLGKTN VPEHPKRVVVLELGFIDTLLDLGITPVGVADDNKAKQLINKDVLKKIDGYTSVGTRSQ PSMEKIASLKPDLIIADTTRHKKVYDQLKKIAPTIALNNLNADYQDTIDASLTIAKAV GKEKEMEKKLTAHEEKLSETKQKISANSQSVLLIGNTNDTIMARDENFFTSRLLTQVG YRYAISTSGNSDSSNGGDSVNMKMTLEQLLKTDPDVIILMTGKTDDLDADGKRPIEKN VLWKKLKAVKNGHVYHVDRAVWSLRRSVDGANAILDELQKEMPAAKK*" gene 1107733..1108704 /gene="yhfQ" /locus_tag="BSU_10330" /old_locus_tag="BSU10330" downshifts 1108683 /Source="Nicolas_upshifts" /id="D563" /incds=0 /nref=172 /ntot=251 /MaxReadThrough="2.22013" /MaxDrop="5.6726" /score="27.9181244" /energy="-10.9" /TU="NA" /idTUdmin="U833" /TUdmin=0 /isTUend="TRUE" CDS complement(1108736..1109317) /gene="phoE" /locus_tag="BSU_10340" /old_locus_tag="BSU10340" /EC_number="3.1.3.-" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:10869096, 11827481, 12870714, 17693564" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10869096, 11827481, 12870714, 17693564; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="promiscuous phosphatase; putative (phosphoglycerate) mutase" /protein_id="NP_388915.1" /db_xref="EnsemblGenomes-Gn:BSU10340" /db_xref="EnsemblGenomes-Tr:CAB12874" /db_xref="GOA:O07617" /db_xref="InterPro:IPR001345" /db_xref="InterPro:IPR013078" /db_xref="InterPro:IPR029033" /db_xref="SubtiList:BG13062" /db_xref="UniProtKB/Swiss-Prot:O07617" /translation="MTAVCLVRHGETDWNLQQKCQGKTDIPLNATGERQARETGEYVK DFSWDIIVTSPLKRAKRTAEIINEYLHLPIVEMDDFKERDYGDAEGMPLEERTKRYPD NIYPNMETLEELTDRLMGGLAKVNQAYPNKKVLIVAHGAAIHALLTEISGGDPELQST RLVNACLSNIEFAEEKWRIKDYNINSHLSGFIK*" gene complement(1108736..1109317) /gene="phoE" /locus_tag="BSU_10340" /old_locus_tag="BSU10340" downshifts complement(1108759) /Source="Nicolas_upshifts" /id="D564" /incds=0 /nref=218 /ntot=256 /MaxReadThrough="1.23197" /MaxDrop="6.359" /score="28.9228703" /energy="-10.9" /TU="NA" /idTUdmin="U834" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(1109341..1109360) /Source="Nicolas_upshift_promotors" /id="U834" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.370629370629371" /psig="0.998001998001998" /xcortree=1973 /SigmaFactorBS="ctttattatttgaagttcttgcataggctttttcATAGgaca cacgctttcgaTTTAGTATAATAGCGATATGaataaagtcaggaaggggattttatga c" /listShort="phoE" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1109353) /Source="Nicolas_upshifts" /id="U834" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.370629370629371" /psig="0.998001998001998" /xcortree=1973 /SigmaFactorBS="ctttattatttgaagttcttgcataggctttttcATAGgaca cacgctttcgaTTTAGTATAATAGCGATATGaataaagtcaggaaggggattttatga c" /listShort="phoE" /GFF_Attribute="listLong" promotor_-35 complement(1109376..1109379) /Source="Nicolas_upshift_promotors" /id="U834" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.370629370629371" /psig="0.998001998001998" /xcortree=1973 /SigmaFactorBS="ctttattatttgaagttcttgcataggctttttcATAGgaca cacgctttcgaTTTAGTATAATAGCGATATGaataaagtcaggaaggggattttatga c" /listShort="phoE" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(1109388..1110482) /gene="yhfS" /locus_tag="BSU_10350" /old_locus_tag="BSU10350" /EC_number="2.3.1.9" /experiment="publication(s) with functional evidences, PMID:12368242, 23840410" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12368242, 23840410; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="acetyl-CoA C-acetyltransferase" /protein_id="NP_388916.1" /db_xref="EnsemblGenomes-Gn:BSU10350" /db_xref="EnsemblGenomes-Tr:CAB12875" /db_xref="GOA:O07618" /db_xref="InterPro:IPR002155" /db_xref="InterPro:IPR016039" /db_xref="InterPro:IPR020613" /db_xref="InterPro:IPR020616" /db_xref="InterPro:IPR020617" /db_xref="SubtiList:BG13063" /db_xref="UniProtKB/Swiss-Prot:O07618" /translation="MNAVIVDAKRTIFGNQNGLLKPFLPEDLAAPIIRCLSRKLEDQV DEVILGNATGRGGNLARLSALQAGLPLSVPGMTIDRQCGSGLEAVRYACSLIQAGAGT MYIAGGSESSSQSPFSERARFSPDAIGDPDMGIAAEYTAARYSISRSMQDEYALLSHQ RSRNAHDEGFYREEVVALGELETDEAFLKTRPIEAIIPRAKPVFDTSSGTVTAANSSG IADGAAALLVMEEEKAAALGLKPVLRFIGSAVSGIHPNFPPAAPVVAIRQLLHTHDVT PDDIDLFEINEAFAVKICVCSQELGIPFSKINVRGGALALGHPYGASGAALVTRLFYE AKRRPDCQYAVAAIGSGGGIGLALLFEVLA*" gene complement(1109388..1110482) /gene="yhfS" /locus_tag="BSU_10350" /old_locus_tag="BSU10350" CDS complement(1110479..1111918) /gene="yhfT" /locus_tag="BSU_10360" /old_locus_tag="BSU10360" /EC_number="6.2.1.-" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 12368242, 28032445, 28414710; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative long-chain fatty-acid-CoA ligase (proofreading for biotin synthesis)" /protein_id="NP_388917.1" /db_xref="EnsemblGenomes-Gn:BSU10360" /db_xref="EnsemblGenomes-Tr:CAB12876" /db_xref="GOA:O07619" /db_xref="InterPro:IPR000873" /db_xref="InterPro:IPR020845" /db_xref="InterPro:IPR025110" /db_xref="SubtiList:BG13064" /db_xref="UniProtKB/Swiss-Prot:O07619" /translation="MTITHTYSSTAETSPGRVAIQTESEQITYHDWDRLVSQTANWLR SQPSMPNRVAILLPNSLAFLQLFAGAAAAGCTAIPIDTRWSPAECKERLSISNADLVV TLAFFKNKLTDSQTPVVLLDNCMADISEAAADPLPTIDPEHPFYMGFTSGSTGKPKAF TRSHRSWMESFTCTETDFSISSDDKVLIPGALMSSHFLYGAVSTLFLGGTVCLLKKFS PAKAKEWLCRESISVLYTVPTMTDALARIEGFPDSPVKIISSGADWPAESKKKLAAAW PHLKLYDFYGTSELSFVTFSSPEDSKRKPHSAGRPFHNVRIEIRNAGGERCQPGEIGK IFVKSPMRFSGYVNGSTPDEWMTVDDMGYVDEEGFLYISGRENGMIVYGGLNIFPEEI ERVLLACPEVESAAVVGIPDEYWGEIAVAVILGNANARTLKAWCKQKLASYKIPKKWV FADSLPETSSGKIARSRVKKWLEESVQYK*" gene complement(1110479..1111918) /gene="yhfT" /locus_tag="BSU_10360" /old_locus_tag="BSU10360" CDS complement(1111925..1112485) /gene="bioY" /locus_tag="BSU_10370" /old_locus_tag="BSU10370" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 12368242, 15849754, 16850406, 18931129, 23709504; Product type t : transporter" /codon_start=1 /transl_table=11 /product="biotin transporter" /protein_id="NP_388918.1" /db_xref="EnsemblGenomes-Gn:BSU10370" /db_xref="EnsemblGenomes-Tr:CAB12877" /db_xref="GOA:O07620" /db_xref="InterPro:IPR003784" /db_xref="SubtiList:BG13065" /db_xref="UniProtKB/Swiss-Prot:O07620" /translation="MLKLIDMMHIAIFTALMAVLGFMPPLFLSFTPVPITLQTLGVML AGSILRPKSAFLSQLVFLLLVAFGAPLLPGGRGGFGVFFGPSAGFLIAYPLASWLISL AANRLRKVTVLRLFFTHIVFGIIFIYLLGIPVQAFIMHIDLSQAAFMSLAYVPGDLIK AAVSAFLAIKITQALSLSDTMFTKGG*" gene complement(1111925..1112485) /gene="bioY" /locus_tag="BSU_10370" /old_locus_tag="BSU10370" misc_feature complement(1111935..1111954) /Source="Nicolas_upshift_promotors" /id="U835" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.585414585414585" /psig="0.97902097902098" /xcortree=2231 /SigmaFactorBS="aaaagcggctgtatctgcatttctggcgataaaaatcactca agccttgtctcttTCTGATACGATGTTTACAAAaggaggatgacaatacatgacaatt a" /listShort="yhfT, yhfS, phoE" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(1111949) /Source="Nicolas_upshifts" /id="U835" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.585414585414585" /psig="0.97902097902098" /xcortree=2231 /SigmaFactorBS="aaaagcggctgtatctgcatttctggcgataaaaatcactca agccttgtctcttTCTGATACGATGTTTACAAAaggaggatgacaatacatgacaatt a" /listShort="yhfT, yhfS, phoE" /GFF_Attribute="listLong" promotor_-10 complement(1112510..1112529) /Source="Nicolas_upshift_promotors" /id="U836" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.977022977022977" /psig="0.999000999001" /xcortree=2919 /SigmaFactorBS="ttgcgttcattatgtaaacttaaattaaaaatcAGTTGACAt aataattacctgcATTTATTGTATAACCATATTtgattactttttggaggatttcaca t" /listShort="bioY, yhfT, yhfS, phoE" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1112524) /Source="Nicolas_upshifts" /id="U836" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.977022977022977" /psig="0.999000999001" /xcortree=2919 /SigmaFactorBS="ttgcgttcattatgtaaacttaaattaaaaatcAGTTGACAt aataattacctgcATTTATTGTATAACCATATTtgattactttttggaggatttcaca t" /listShort="bioY, yhfT, yhfS, phoE" /GFF_Attribute="listLong" promotor_-35 complement(1112544..1112551) /Source="Nicolas_upshift_promotors" /id="U836" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.977022977022977" /psig="0.999000999001" /xcortree=2919 /SigmaFactorBS="ttgcgttcattatgtaaacttaaattaaaaatcAGTTGACAt aataattacctgcATTTATTGTATAACCATATTtgattactttttggaggatttcaca t" /listShort="bioY, yhfT, yhfS, phoE" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(1112620..1113918) /gene="hemAT" /locus_tag="BSU_10380" /old_locus_tag="BSU10380" /function="16.12: Sense" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:11481493, 12657801, 12962628, 15033535, 16819829, 17003124, 22528495, 22564695" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11481493, 12657801, 12962628, 15033535, 16819829, 17003124, 22528495, 22564695; Product type rc: receptor" /codon_start=1 /transl_table=11 /product="heme-based dioxygen sensor" /protein_id="NP_388919.1" /db_xref="EnsemblGenomes-Gn:BSU10380" /db_xref="EnsemblGenomes-Tr:CAB12878" /db_xref="GOA:O07621" /db_xref="InterPro:IPR004089" /db_xref="InterPro:IPR009050" /db_xref="PDB:1OR4" /db_xref="PDB:1OR6" /db_xref="SubtiList:BG13066" /db_xref="UniProtKB/Swiss-Prot:O07621" /translation="MLFKKDRKQETAYFSDSNGQQKNRIQLTNKHADVKKQLKMVRLG DAELYVLEQLQPLIQENIVNIVDAFYKNLDHESSLMDIINDHSSVDRLKQTLKRHIQE MFAGVIDDEFIEKRNRIASIHLRIGLLPKWYMGAFQELLLSMIDIYEASITNQQELLK AIKATTKILNLEQQLVLEAFQSEYNQTRDEQEEKKNLLHQKIQETSGSIANLFSETSR SVQELVDKSEGISQASKAGTVTSSTVEEKSIGGKKELEVQQKQMNKIDTSLVQIEKEM VKLDEIAQQIEKIFGIVTGIAEQTNLLSLNASIESARAGEHGKGFAVVANEVRKLSED TKKTVSTVSELVNNTNTQINIVSKHIKDVNELVSESKEKMTQINRLFDEIVHSMKISK EQSGKIDVDLQAFLGGLQEVSRAVSHVAASVDSLVILTEE*" gene complement(1112620..1113918) /gene="hemAT" /locus_tag="BSU_10380" /old_locus_tag="BSU10380" downshifts complement(1112631) /Source="Nicolas_upshifts" /id="D565" /incds=0 /nref=209 /ntot=243 /MaxReadThrough="2.70691" /MaxDrop="6.97357" /score="5.86442746" /energy="-6.9" /TU="NA" /idTUdmin="U837" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(1113972..1113990) /Source="Nicolas_upshift_promotors" /id="U837" /multdbtbs="SigD" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2810 /SigmaFactorBS="tttttcaaatatttttcatctgcagCTTCATTcatgtttccc ttgGCCGATAAAAAAGAAAAAGgcttaaaaagccaaaaagtaaaaattatatttttcc c" /listShort="hemAT" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1113975) /Source="Nicolas_upshifts" /id="U837" /multdbtbs="SigD" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2810 /SigmaFactorBS="tttttcaaatatttttcatctgcagCTTCATTcatgtttccc ttgGCCGATAAAAAAGAAAAAGgcttaaaaagccaaaaagtaaaaattatatttttcc c" /listShort="hemAT" /GFF_Attribute="listLong" promotor_-35 complement(1114004..1114010) /Source="Nicolas_upshift_promotors" /id="U837" /multdbtbs="SigD" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2810 /SigmaFactorBS="tttttcaaatatttttcatctgcagCTTCATTcatgtttccc ttgGCCGATAAAAAAGAAAAAGgcttaaaaagccaaaaagtaaaaattatatttttcc c" /listShort="hemAT" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(1114057..1115586) /gene="yhfW" /locus_tag="BSU_10390" /old_locus_tag="BSU10390" /EC_number="1.-.-.-" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative oxidoreductase with Rieske [2Fe-2S] center" /protein_id="NP_388920.1" /db_xref="EnsemblGenomes-Gn:BSU10390" /db_xref="EnsemblGenomes-Tr:CAB12879" /db_xref="GOA:O07622" /db_xref="InterPro:IPR005805" /db_xref="InterPro:IPR006076" /db_xref="InterPro:IPR017941" /db_xref="InterPro:IPR036188" /db_xref="InterPro:IPR036922" /db_xref="SubtiList:BG13067" /db_xref="UniProtKB/Swiss-Prot:O07622" /translation="MANQHFAKEAPETYWKTSTDLPSFPALQEDTECDVTIIGGGITG ITTAYELTKRGFRVVLIEANQVLNGTTAHTTAKVTAQHDMIYDEFIRHFGLNHARLYY EANQNAIDYIKGIVDEHQIDCEWIEQDAYLYTANENAVQKIHTEHEAYTKLGIERDLI KDLPIPLGSKLALVMKNQAQFHPLQYLKALLEQIVQKGGRIYEETVALDIKKGERPEV VTKSRHAIKSRFIICCSHFPFYDGGGLYAARMYSDRSYVLAIKPKIEYPEGMYLSIDQ PSVALRYTVVNGEKLILFSGVSHKTGQGKAMSTHYETLRQLAESTIGIESIPYYWSTQ DLVTIDKIPFIGPMSENEDNILVATGFKKWGMTSSAVAATLLSDLVEKKENPYESIFT PSRFHLNPGLQKVISYNADVAKHLIKGKLEKPDVQFEDISPGEGKAVTINGRRAGAFR DETGCLHLVDTTCTHLGCEVEWNDSEHTWDCPCHGSRFKPSGEVVEGPAIKPLKQIDL D*" gene complement(1114057..1115586) /gene="yhfW" /locus_tag="BSU_10390" /old_locus_tag="BSU10390" promotor_-10 complement(1115613..1115631) /Source="Nicolas_upshift_promotors" /id="U838" /multdbtbs="SigF" /comp="M3" /sig="SigEF" /pcomp="0.84015984015984" /psig="0.84015984015984" /xcortree=1075 /SigmaFactorBS="ttcaaccttattatgttatgaacaatgcctgcTTCCTAtgta tgaaaagataGAATATGGAAAAATTAAGAataaatctgattggaggtataacggcttg g" /listShort="yhfW, hemAT" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1115623) /Source="Nicolas_upshifts" /id="U838" /multdbtbs="SigF" /comp="M3" /sig="SigEF" /pcomp="0.84015984015984" /psig="0.84015984015984" /xcortree=1075 /SigmaFactorBS="ttcaaccttattatgttatgaacaatgcctgcTTCCTAtgta tgaaaagataGAATATGGAAAAATTAAGAataaatctgattggaggtataacggcttg g" /listShort="yhfW, hemAT" /GFF_Attribute="listLong" promotor_-35 1115642..1115647 /Source="Nicolas_upshift_promotors" /id="U839" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.99100899100899" /psig="0.99100899100899" /xcortree=1100 /SigmaFactorBS="ccaatcagatttattcttaatttttccatattctatcttttc aTACATAggaagcaggcattgtTCATAACATAATAAGGTTGaaaaggagtgatttcat t" /listShort="yhxC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 complement(1115646..1115651) /Source="Nicolas_upshift_promotors" /id="U838" /multdbtbs="SigF" /comp="M3" /sig="SigEF" /pcomp="0.84015984015984" /psig="0.84015984015984" /xcortree=1075 /SigmaFactorBS="ttcaaccttattatgttatgaacaatgcctgcTTCCTAtgta tgaaaagataGAATATGGAAAAATTAAGAataaatctgattggaggtataacggcttg g" /listShort="yhfW, hemAT" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 1115659 /Source="Nicolas_upshifts" /id="U839" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.99100899100899" /psig="0.99100899100899" /xcortree=1100 /SigmaFactorBS="ccaatcagatttattcttaatttttccatattctatcttttc aTACATAggaagcaggcattgtTCATAACATAATAAGGTTGaaaaggagtgatttcat t" /listShort="yhxC" /GFF_Attribute="listLong" promotor_-10 1115663..1115681 /Source="Nicolas_upshift_promotors" /id="U839" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.99100899100899" /psig="0.99100899100899" /xcortree=1100 /SigmaFactorBS="ccaatcagatttattcttaatttttccatattctatcttttc aTACATAggaagcaggcattgtTCATAACATAATAAGGTTGaaaaggagtgatttcat t" /listShort="yhxC" /GFF_Attribute="listLong" /label="promotor_-10" CDS 1115698..1116555 /gene="yhxC" /locus_tag="BSU_10400" /old_locus_tag="BSU10400" /EC_number="1.-.-.-" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 18643936, 25720121; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative oxidoreductase" /protein_id="NP_388921.1" /db_xref="EnsemblGenomes-Gn:BSU10400" /db_xref="EnsemblGenomes-Tr:CAB12880" /db_xref="GOA:P40397" /db_xref="InterPro:IPR002347" /db_xref="InterPro:IPR020904" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG11058" /db_xref="UniProtKB/Swiss-Prot:P40397" /translation="MANQKKKTLPPQHQNQQPGFEYLMDPRPVFDKPKKAKKLEGKTA IITGGDSGIGRAVSVLFAKEGANVVIVYLNEHQDAEETKQYVEKEGVKCLLIAGDVGD EAFCNDVVGQASQVFPSIDILVNNAAEQHVQPSIEKITSHQLIRTFQTNIFSMFYLTK AVLPHLKKGSSIINTASITAYKGNKTLIDYSATKGAIVTFTRSLSQSLVQQGIRVNAV APGPIWTPLIPASFAAKDVEVFGSDVPMERPGQPVEVAPSYLYLASDDSTYVTGQTIH VNGGTIVNG*" gene 1115698..1116555 /gene="yhxC" /locus_tag="BSU_10400" /old_locus_tag="BSU10400" downshifts 1116537 /Source="Nicolas_upshifts" /id="D566" /incds=0 /nref=10 /ntot=36 /MaxReadThrough="2.65833" /MaxDrop="4.80135" /score="-8.69335909" /energy="-4.5" /TU="NA" /idTUdmin="U839" /TUdmin=0 /isTUend="TRUE" CDS complement(1116583..1116816) /gene="yhzC" /locus_tag="BSU_10410" /old_locus_tag="BSU10410" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_388922.1" /db_xref="EnsemblGenomes-Gn:BSU10410" /db_xref="EnsemblGenomes-Tr:CAB12881" /db_xref="InterPro:IPR014957" /db_xref="SubtiList:BG13087" /db_xref="UniProtKB/Swiss-Prot:O31594" /translation="MKEKKSYTELMKSRNTQKTKEFDVTMTDIYIQMVLDESLYNRRL AMLTDQINKALDEKDKDAFLTLSKEYAALKQSE*" gene complement(1116583..1116816) /gene="yhzC" /locus_tag="BSU_10410" /old_locus_tag="BSU10410" downshifts complement(1116616) /Source="Nicolas_upshifts" /id="D567" /incds=0 /nref=191 /ntot=247 /MaxReadThrough="3.34616" /MaxDrop="7.00218" /score="21.4902337" /energy="-12.3" /TU="U841" /idTUdmin="U844" /TUdmin="-3" /isTUend="TRUE" promotor_-10 complement(1116833..1116852) /Source="Nicolas_upshift_promotors" /id="U841" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.914085914085914" /psig="0.999000999001" /xcortree=2872 /SigmaFactorBS="atagattgccaagtattagttgtctaaaaattataaaaattT ATTGATTttttcgaccgttatCCATATACTATAAAAAAGGCattggggggattcttta t" /listShort="yhzC" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 1116836..1116837 /Source="Nicolas_upshift_promotors" /id="U840" /multdbtbs="-" /comp="M3" /sig="Sig-" /pcomp="0.422577422577423" /psig="0.422577422577423" /xcortree=1052 /SigmaFactorBS="cgggacttcatgagctcagtgtacgattttttctctttcata aagaatccccccaatgccTTttTTATAGTATATGGATAacggtcgaaaaaatcaataa a" /listShort="comK" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 1116836 /Source="Nicolas_upshifts" /id="U840" /multdbtbs="-" /comp="M3" /sig="Sig-" /pcomp="0.422577422577423" /psig="0.422577422577423" /xcortree=1052 /SigmaFactorBS="cgggacttcatgagctcagtgtacgattttttctctttcata aagaatccccccaatgccTTttTTATAGTATATGGATAacggtcgaaaaaatcaataa a" /listShort="comK" /GFF_Attribute="listLong" promotor_-10 1116840..1116855 /Source="Nicolas_upshift_promotors" /id="U840" /multdbtbs="-" /comp="M3" /sig="Sig-" /pcomp="0.422577422577423" /psig="0.422577422577423" /xcortree=1052 /SigmaFactorBS="cgggacttcatgagctcagtgtacgattttttctctttcata aagaatccccccaatgccTTttTTATAGTATATGGATAacggtcgaaaaaatcaataa a" /listShort="comK" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1116855) /Source="Nicolas_upshifts" /id="U841" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.914085914085914" /psig="0.999000999001" /xcortree=2872 /SigmaFactorBS="atagattgccaagtattagttgtctaaaaattataaaaattT ATTGATTttttcgaccgttatCCATATACTATAAAAAAGGCattggggggattcttta t" /listShort="yhzC" /GFF_Attribute="listLong" S_feature complement(1116857..1117712) /Source="Nicolas_S_feature" /locus_tag="new_1116857_1117712_c" /HighExp="Salt, Etha, C30, Heat, S8, LPhT, Gly, C90, S7, UNK1" /AntisenseName="comK" /AntisenseCor="-5.68778941053006E-2" /AntisenseRegPval="-0.5" /CDS_PredictionProba="NA" /TUshortSig="SigB" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S365" promotor_-35 complement(1116867..1116874) /Source="Nicolas_upshift_promotors" /id="U841" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.914085914085914" /psig="0.999000999001" /xcortree=2872 /SigmaFactorBS="atagattgccaagtattagttgtctaaaaattataaaaattT ATTGATTttttcgaccgttatCCATATACTATAAAAAAGGCattggggggattcttta t" /listShort="yhzC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1117039..1117046 /Source="Nicolas_upshift_promotors" /id="U842" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.747252747252747" /psig="0.997002997002997" /xcortree=2958 /SigmaFactorBS="ttaaaagatgattttatcttaaatgttaaaaaaacCTGTCGT TttacaaaaacaGATGATAGATTATTAGTATAaattttgcagaaaaaggatggaggcc a" /listShort="comK, S366, S367" /listLong="yhjA" /label="promotor_-35" promotor_-10 1117058..1117077 /Source="Nicolas_upshift_promotors" /id="U842" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.747252747252747" /psig="0.997002997002997" /xcortree=2958 /SigmaFactorBS="ttaaaagatgattttatcttaaatgttaaaaaaacCTGTCGT TttacaaaaacaGATGATAGATTATTAGTATAaattttgcagaaaaaggatggaggcc a" /listShort="comK, S366, S367" /listLong="yhjA" /label="promotor_-10" upshifts 1117064 /Source="Nicolas_upshifts" /id="U842" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.747252747252747" /psig="0.997002997002997" /xcortree=2958 /SigmaFactorBS="ttaaaagatgattttatcttaaatgttaaaaaaacCTGTCGT TttacaaaaacaGATGATAGATTATTAGTATAaattttgcagaaaaaggatggaggcc a" /listShort="comK, S366, S367" /listLong="yhjA" CDS 1117109..1117687 /gene="comK" /locus_tag="BSU_10420" /old_locus_tag="BSU10420" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:15743949, 15819619, 16554821, 16907804, 17468244, 26091431, 27501195, 27920766" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15743949, 15819619, 16554821, 16907804, 17468244, 26091431, 27501195, 27920766; Product type r: regulator" /codon_start=1 /transl_table=11 /product="competence transcription factor (CTF)" /protein_id="NP_388923.1" /db_xref="EnsemblGenomes-Gn:BSU10420" /db_xref="EnsemblGenomes-Tr:CAB12882" /db_xref="GOA:P40396" /db_xref="InterPro:IPR010461" /db_xref="SubtiList:BG11059" /db_xref="UniProtKB/Swiss-Prot:P40396" /translation="MSQKTDAPLESYEVNGATIAVLPEEIDGKICSKIIEKDCVFYVN MKPLQIVDRSCRFFGSSYAGRKAGTYEVTKISHKPPIMVDPSNQIFLFPTLSSTRPQC GWISHVHVKEFKATEFDDTEVTFSNGKTMELPISYNSFENQVYRTAWLRTKFQDRIDH RVPKRQEFMLYPKEERTKMIYDFILRELGERY*" gene 1117109..1117687 /gene="comK" /locus_tag="BSU_10420" /old_locus_tag="BSU10420" S_feature 1117688..1117833 /Source="Nicolas_S_feature" /locus_tag="new_1117688_1117833" /HighExp="GM 150, C30, T-4.40H, T-3.40H, GM 120, M9-tran, T-2.40H, C90, G/S, T-1.10H" /AntisenseName="yhxD" /AntisenseCor="-0.229484184862048" /AntisenseRegPval="-3.8" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.997" /TUlongSig="NA" /TUlongPSig="NA" /label="S366" CDS complement(1117734..1118633) /gene="yhxD" /locus_tag="BSU_10430" /old_locus_tag="BSU10430" /EC_number="1.-.-.-" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative oxidoreductase" /protein_id="NP_388924.1" /db_xref="EnsemblGenomes-Gn:BSU10430" /db_xref="EnsemblGenomes-Tr:CAB12883" /db_xref="GOA:P40398" /db_xref="InterPro:IPR002347" /db_xref="InterPro:IPR020904" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG11060" /db_xref="UniProtKB/Swiss-Prot:P40398" /translation="MSDSNLTNPIKAFFHDEFPEQYQEPPGLQKNMKPVPDCGEKSYK GSGKLTGRKALVTGGDSGIGRAAAIAYAREGADVAINYLPEEQPDAEEVKELIEAEGR KAVLIPGDLSDESFCQDLVKQSHHELGGLDVLALVAGKQQAVENIEDLPTEQIYKTFE VNVFSLYWVVKAALPYLPEGASIITTTSVEGYNPSPMLLDYAATKNAIIGFTVGLGKQ LASKGIRVNSVAPGPIWTPLQISGGQPTENIPKFGQGTPPAPLNRAGQPVELADVYVF LASENSSYVTSQVYGITGGIPTA*" gene complement(1117734..1118633) /gene="yhxD" /locus_tag="BSU_10430" /old_locus_tag="BSU10430" downshifts complement(1117757) /Source="Nicolas_upshifts" /id="D568" /incds=0 /nref=7 /ntot=53 /MaxReadThrough="4.95535" /MaxDrop="4.1467" /score="-2.68458203" /energy="-14.6" /TU="U844" /idTUdmin="U844" /TUdmin="-1144" /isTUend="FALSE" promotor_-35 1117820..1117823 /Source="Nicolas_upshift_promotors" /id="U843" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.95104895104895" /psig="0.010989010989011" /xcortree=17 /SigmaFactorBS="atgtcacatagcttgaattctctgaagctagaaatacataaa catCGGCcaattccactggctgccCAGCGcgatttaatggagctggcggcgtgccttg t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 1117835 /Source="Nicolas_upshifts" /id="U843" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.95104895104895" /psig="0.010989010989011" /xcortree=17 /SigmaFactorBS="atgtcacatagcttgaattctctgaagctagaaatacataaa catCGGCcaattccactggctgccCAGCGcgatttaatggagctggcggcgtgccttg t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 1117841..1117845 /Source="Nicolas_upshift_promotors" /id="U843" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.95104895104895" /psig="0.010989010989011" /xcortree=17 /SigmaFactorBS="atgtcacatagcttgaattctctgaagctagaaatacataaa catCGGCcaattccactggctgccCAGCGcgatttaatggagctggcggcgtgccttg t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" downshifts 1117879 /Source="Nicolas_upshifts" /id="D569" /incds=1 /nref=1 /ntot=5 /MaxReadThrough="5.45904" /MaxDrop="5.6543" /score="-8.69335909" /energy="-4.5" /TU="U842" /idTUdmin="U843" /TUdmin=0 /isTUend="TRUE" S_feature 1117924..1118790 /Source="Nicolas_S_feature" /locus_tag="new_1117924_1118790" /HighExp="GM 150, C30, T-4.40H, C90, T-3.40H, T-2.40H, G/S, T-5.40H, M9-tran, nit" /AntisenseName="yhxD" /AntisenseCor="-0.32746434250834699" /AntisenseRegPval="-7.4" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.997" /TUlongSig="NA" /TUlongPSig="NA" /label="S367" promotor_-10 complement(1118660..1118678) /Source="Nicolas_upshift_promotors" /id="U844" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=190 /SigmaFactorBS="tgttttctttttccttcactattcaaactgccaaaacaTGTT TTTctgcttatgctcagGGGTACACATACGAATGTAcaccaaacagaaaaggagcgtt g" /listShort="yhxD, S365, yhzC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1118677) /Source="Nicolas_upshifts" /id="U844" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=190 /SigmaFactorBS="tgttttctttttccttcactattcaaactgccaaaacaTGTT TTTctgcttatgctcagGGGTACACATACGAATGTAcaccaaacagaaaaggagcgtt g" /listShort="yhxD, S365, yhzC" /GFF_Attribute="listLong" promotor_-35 complement(1118693..1118699) /Source="Nicolas_upshift_promotors" /id="U844" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=190 /SigmaFactorBS="tgttttctttttccttcactattcaaactgccaaaacaTGTT TTTctgcttatgctcagGGGTACACATACGAATGTAcaccaaacagaaaaggagcgtt g" /listShort="yhxD, S365, yhzC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1118767..1118774 /Source="Nicolas_upshift_promotors" /id="U845" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.866133866133866" /psig=1 /xcortree=2715 /SigmaFactorBS="aaaacaagaaaaaacaaagccttcttccatatttaTCTTGTC AaataagactatatgAATTATGATAAATTCGAGCTataaatcaactaaatattgggtg t" /listShort="yhjA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1118789..1118808 /Source="Nicolas_upshift_promotors" /id="U845" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.866133866133866" /psig=1 /xcortree=2715 /SigmaFactorBS="aaaacaagaaaaaacaaagccttcttccatatttaTCTTGTC AaataagactatatgAATTATGATAAATTCGAGCTataaatcaactaaatattgggtg t" /listShort="yhjA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1118792 /Source="Nicolas_upshifts" /id="U845" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.866133866133866" /psig=1 /xcortree=2715 /SigmaFactorBS="aaaacaagaaaaaacaaagccttcttccatatttaTCTTGTC AaataagactatatgAATTATGATAAATTCGAGCTataaatcaactaaatattgggtg t" /listShort="yhjA" /GFF_Attribute="listLong" CDS 1118850..1119119 /gene="yhjA" /locus_tag="BSU_10440" /old_locus_tag="BSU10440" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_388925.1" /db_xref="EnsemblGenomes-Gn:BSU10440" /db_xref="EnsemblGenomes-Tr:CAB12884" /db_xref="InterPro:IPR008613" /db_xref="SubtiList:BG13068" /db_xref="UniProtKB/Swiss-Prot:O07555" /translation="MKKAAAVLLSLGLVFGFSYGAGHVAEAKTKVKVYKNCKELNKVY KGGVARTSKVKNKGGKTKYKPYVSKALYDANKNKDRDKDLIACER*" gene 1118850..1119119 /gene="yhjA" /locus_tag="BSU_10440" /old_locus_tag="BSU10440" downshifts 1119111 /Source="Nicolas_upshifts" /id="D570" /incds=0 /nref=230 /ntot=267 /MaxReadThrough="2.67325" /MaxDrop="7.59695" /score="27.4895724" /energy="-11.2" /TU="NA" /idTUdmin="U845" /TUdmin=0 /isTUend="TRUE" downshifts complement(1119159) /Source="Nicolas_upshifts" /id="D571" /incds=0 /nref=11 /ntot=113 /MaxReadThrough="2.40747" /MaxDrop="4.60953" /score="20.2036192" /energy="-11.2" /TU="NA" /idTUdmin="U846" /TUdmin=6 /isTUend="TRUE" CDS complement(1119162..1120631) /gene="yhjB" /locus_tag="BSU_10450" /old_locus_tag="BSU10450" /function="16.1: Circulate" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16267290, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative Na+/metabolite cotransporter" /protein_id="NP_388926.1" /db_xref="EnsemblGenomes-Gn:BSU10450" /db_xref="EnsemblGenomes-Tr:CAB12885" /db_xref="GOA:O07556" /db_xref="InterPro:IPR001734" /db_xref="SubtiList:BG13069" /db_xref="UniProtKB/Swiss-Prot:O07556" /translation="MNAALIIIFGVLLLSIFLGIRAQKGKDMNLEQWTVGGRGFGTVF VFLLMAGEIYTTFTFLGGSGWAYGKGGPAFYIIAYGCLAYILSYWLLPAVWTYAKQHK LMSQSDFFTKKYNSPLLGILVSLVGIAALIPYLVLQLKGLGLIVSETSYGKITPTAAI WIGAVSITVYVMVSGIHGSAWISVVKDIMILVVVLFLGVYLPIHYYGGFQDMFQQIET AKPGFLTLPESGQSVAWFSSTVLLTALGFYMWPHTFSASYSAENPKVFRKNAIIMPLY QLVLLFVLFVGFAAILQVPDLNGADGDLSLLRLSLQAFDPWFVGIIGAAGLLTALVPG SMILMSASTLFAKNVYKVIAPRTTEQQVSALAKFLVPVIALISVYFTFKGGNTIVTLL LMGYSLVTQLFPALLFSLLKHNMVTKQGAFAGIIAGVGAVTYITMTETTIGTLFPALP QAAKDLNVGIVALLLNITVMMAVSLMTRKAKSAAADQAA*" gene complement(1119162..1120631) /gene="yhjB" /locus_tag="BSU_10450" /old_locus_tag="BSU10450" CDS complement(1120628..1120828) /gene="yhjC" /locus_tag="BSU_10460" /old_locus_tag="BSU10460" /function="16.1: Circulate" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 16267290; Product type f: factor" /codon_start=1 /transl_table=11 /product="putative exported protein" /protein_id="NP_388927.1" /db_xref="EnsemblGenomes-Gn:BSU10460" /db_xref="EnsemblGenomes-Tr:CAB12886" /db_xref="GOA:O07557" /db_xref="InterPro:IPR021741" /db_xref="SubtiList:BG13070" /db_xref="UniProtKB/Swiss-Prot:O07557" /translation="MKLIHVLAALPFIGILLGIPFANKVTPYVFGMPFILAYIVMWAL LTSALMAIVYVLDKENKKEEAE*" gene complement(1120628..1120828) /gene="yhjC" /locus_tag="BSU_10460" /old_locus_tag="BSU10460" S_feature complement(1120829..1120947) /Source="Nicolas_S_feature" /locus_tag="new_1120829_1120947_c" /HighExp="S1, Etha, HiOs, MG 120, LoTm, T-5.40H, S2, GM-0.1, GM-0.2, T0.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="1, 0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S368" promotor_-10 complement(1120930..1120949) /Source="Nicolas_upshift_promotors" /id="U846" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.574425574425574" /psig=1 /xcortree=2904 /SigmaFactorBS="cttcgggcgattcagagcattaatttcagacaattcacACTA TACAaacaaaataaatTTATTTATAATTCGAACCACagcctttcactccaaaaaatga c" /listShort="S368, yhjC, yhjB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1120947) /Source="Nicolas_upshifts" /id="U846" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.574425574425574" /psig=1 /xcortree=2904 /SigmaFactorBS="cttcgggcgattcagagcattaatttcagacaattcacACTA TACAaacaaaataaatTTATTTATAATTCGAACCACagcctttcactccaaaaaatga c" /listShort="S368, yhjC, yhjB" /GFF_Attribute="listLong" promotor_-35 complement(1120962..1120969) /Source="Nicolas_upshift_promotors" /id="U846" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.574425574425574" /psig=1 /xcortree=2904 /SigmaFactorBS="cttcgggcgattcagagcattaatttcagacaattcacACTA TACAaacaaaataaatTTATTTATAATTCGAACCACagcctttcactccaaaaaatga c" /listShort="S368, yhjC, yhjB" /GFF_Attribute="listLong" /label="promotor_-35" downshifts complement(1121035) /Source="Nicolas_upshifts" /id="D572" /incds=0 /nref=1 /ntot=8 /MaxReadThrough="3.99656" /MaxDrop="2.67326" /score="20.2036192" /energy="-11.2" /TU="U848" /idTUdmin="U848" /TUdmin="-374" /isTUend="FALSE" CDS complement(1121036..1121398) /gene="yhjD" /locus_tag="BSU_10470" /old_locus_tag="BSU10470" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 16267290" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_388928.1" /db_xref="EnsemblGenomes-Gn:BSU10470" /db_xref="EnsemblGenomes-Tr:CAB12887" /db_xref="GOA:O07558" /db_xref="SubtiList:BG13071" /db_xref="UniProtKB/Swiss-Prot:O07558" /translation="MPNLQEEIYDLIERALFLPMAITIFNRDLAGIEESTLKLKHPYK QLISESLKIAQKDLMEVRKELRKRKIAIRETERDEAFTLYTFVIDGYEENHRYFNPRI REQVSELLTYYLFAPDRL*" gene complement(1121036..1121398) /gene="yhjD" /locus_tag="BSU_10470" /old_locus_tag="BSU10470" promotor_-35 1121236..1121241 /Source="Nicolas_upshift_promotors" /id="U847" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.963036963036963" /psig="0.963036963036963" /xcortree=1144 /SigmaFactorBS="tttcctcagttcttttctgacctccatcaaatccttttGTGC TAtttttaatgattcgcTGATAAGCTGTTTATAAGGatgcttcaattttaatgtgctt t" /listShort="S369, yhjE, sipV" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1121257..1121275 /Source="Nicolas_upshift_promotors" /id="U847" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.963036963036963" /psig="0.963036963036963" /xcortree=1144 /SigmaFactorBS="tttcctcagttcttttctgacctccatcaaatccttttGTGC TAtttttaatgattcgcTGATAAGCTGTTTATAAGGatgcttcaattttaatgtgctt t" /listShort="S369, yhjE, sipV" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1121258 /Source="Nicolas_upshifts" /id="U847" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.963036963036963" /psig="0.963036963036963" /xcortree=1144 /SigmaFactorBS="tttcctcagttcttttctgacctccatcaaatccttttGTGC TAtttttaatgattcgcTGATAAGCTGTTTATAAGGatgcttcaattttaatgtgctt t" /listShort="S369, yhjE, sipV" /GFF_Attribute="listLong" S_feature 1121267..1121506 /Source="Nicolas_S_feature" /locus_tag="new_1121267_1121506" /HighExp="S6, S4, S8, S5, LoTm, B36, S3, S7, BT, B60" /AntisenseName="yhjD" /AntisenseCor="0.24202608585419999" /AntisenseRegPval="-4.2" /CDS_PredictionProba="NA" /TUshortSig="SigEF" /TUshortPSig="0.963" /TUlongSig="NA" /TUlongPSig="NA" /label="S369" promotor_-10 complement(1121428..1121447) /Source="Nicolas_upshift_promotors" /id="U848" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.975024975024975" /psig="0.999000999001" /xcortree=1502 /SigmaFactorBS="tcagcagaaaactaaaaagttttggtgattttttctgTCTTG AAAcatttcaccagccgATATAGAATACAAATAGAACaaacgttcccttagaaagaag g" /listShort="yhjD, S368, yhjC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1121446) /Source="Nicolas_upshifts" /id="U848" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.975024975024975" /psig="0.999000999001" /xcortree=1502 /SigmaFactorBS="tcagcagaaaactaaaaagttttggtgattttttctgTCTTG AAAcatttcaccagccgATATAGAATACAAATAGAACaaacgttcccttagaaagaag g" /listShort="yhjD, S368, yhjC" /GFF_Attribute="listLong" promotor_-35 complement(1121462..1121469) /Source="Nicolas_upshift_promotors" /id="U848" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.975024975024975" /psig="0.999000999001" /xcortree=1502 /SigmaFactorBS="tcagcagaaaactaaaaagttttggtgattttttctgTCTTG AAAcatttcaccagccgATATAGAATACAAATAGAACaaacgttcccttagaaagaag g" /listShort="yhjD, S368, yhjC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1121488..1121495 /Source="Nicolas_upshift_promotors" /id="U849" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.711288711288711" /psig="0.998001998001998" /xcortree=619 /SigmaFactorBS="cggctggtgaaatgtttcaagacagaaaaaatcaccaaaaCT TTTTAGttttctgctgataATGTGTAGAATAAGGATAGAcaaacccggtaaggagtat a" /listShort="yhjE, sipV" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 1121508 /Source="Nicolas_upshifts" /id="U849" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.711288711288711" /psig="0.998001998001998" /xcortree=619 /SigmaFactorBS="cggctggtgaaatgtttcaagacagaaaaaatcaccaaaaCT TTTTAGttttctgctgataATGTGTAGAATAAGGATAGAcaaacccggtaaggagtat a" /listShort="yhjE, sipV" /GFF_Attribute="listLong" promotor_-10 1121509..1121528 /Source="Nicolas_upshift_promotors" /id="U849" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.711288711288711" /psig="0.998001998001998" /xcortree=619 /SigmaFactorBS="cggctggtgaaatgtttcaagacagaaaaaatcaccaaaaCT TTTTAGttttctgctgataATGTGTAGAATAAGGATAGAcaaacccggtaaggagtat a" /listShort="yhjE, sipV" /GFF_Attribute="listLong" /label="promotor_-10" CDS 1121550..1122173 /gene="yhjE" /locus_tag="BSU_10480" /old_locus_tag="BSU10480" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative integral membrane protein" /protein_id="NP_388929.1" /db_xref="EnsemblGenomes-Gn:BSU10480" /db_xref="EnsemblGenomes-Tr:CAB12888" /db_xref="GOA:O07559" /db_xref="InterPro:IPR015414" /db_xref="InterPro:IPR032816" /db_xref="SubtiList:BG13072" /db_xref="UniProtKB/Swiss-Prot:O07559" /translation="MLEHFLSYLTQEHLTELFQSYRAFGPLIAVLLPLIEAFLPFLPL IVFVVANTNSFGLWEGFILSWAGSTAGSILVFLIVRQYGQRKLLGFIRSHPSVRKLML WVERHGFGPMFLLLCFPFTPSAAVNVVAGLSRIGTRPFILAAASGKLVMIFMISFIGY DLHALITQPIRTVIAVLVITVLWYVGKKVERYLHVRASQREHDGGRQ*" gene 1121550..1122173 /gene="yhjE" /locus_tag="BSU_10480" /old_locus_tag="BSU10480" CDS 1122175..1122681 /gene="sipV" /locus_tag="BSU_10490" /old_locus_tag="BSU10490" /EC_number="3.4.21.89" /function="16.13: Shape" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:9325333, 9694797, 11309398, 12897006, 14568161, 27159567" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9325333, 9694797, 11309398, 12897006, 14568161, 27159567; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="type I signal peptidase" /protein_id="NP_388930.1" /db_xref="EnsemblGenomes-Gn:BSU10490" /db_xref="EnsemblGenomes-Tr:CAB12889" /db_xref="GOA:O07560" /db_xref="InterPro:IPR000223" /db_xref="InterPro:IPR015927" /db_xref="InterPro:IPR019756" /db_xref="InterPro:IPR019757" /db_xref="InterPro:IPR019758" /db_xref="InterPro:IPR036286" /db_xref="SubtiList:BG12674" /db_xref="UniProtKB/Swiss-Prot:O07560" /translation="MKKRFWFLAGVVSVVLAIQVKNAVFIDYKVEGVSMNPTFQEGNE LLVNKFSHRFKTIHRFDIVLFKGPDHKVLIKRVIGLPGETIKYKDDQLYVNGKQVAEP FLKHLKSVSAGSHVTGDFSLKDVTGTSKVPKGKYFVVGDNRIYSFDSRHFGPIREKNI VGVISDAE*" gene 1122175..1122681 /gene="sipV" /locus_tag="BSU_10490" /old_locus_tag="BSU10490" downshifts 1122674 /Source="Nicolas_upshifts" /id="D573" /incds=0 /nref=131 /ntot=250 /MaxReadThrough="0.63331" /MaxDrop="4.58282" /score="-7.37718733" /energy="-7.1" /TU="NA" /idTUdmin="U847" /TUdmin=0 /isTUend="TRUE" promotor_-35 1122732..1122739 /Source="Nicolas_upshift_promotors" /id="U850" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.662337662337662" /psig=1 /xcortree=2713 /SigmaFactorBS="cgtctttttgtatgccgtttggaaaaatgtGTTGAAGAaaaa tttgtaaggAGCTATAATCAAAATTGTTAcctgtgtaacaaaatttatatattttttt g" /listShort="S370, yhjG, yhjH" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1122753..1122772 /Source="Nicolas_upshift_promotors" /id="U850" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.662337662337662" /psig=1 /xcortree=2713 /SigmaFactorBS="cgtctttttgtatgccgtttggaaaaatgtGTTGAAGAaaaa tttgtaaggAGCTATAATCAAAATTGTTAcctgtgtaacaaaatttatatattttttt g" /listShort="S370, yhjG, yhjH" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 1122762..1122861 /Source="Nicolas_S_feature" /locus_tag="new_1122762_1122861" /HighExp="LBGstat, LBGexp, Lbtran, C90, dia0, Lbexp, HPh, dia5, aero, LBGtran" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S370" upshifts 1122762 /Source="Nicolas_upshifts" /id="U850" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.662337662337662" /psig=1 /xcortree=2713 /SigmaFactorBS="cgtctttttgtatgccgtttggaaaaatgtGTTGAAGAaaaa tttgtaaggAGCTATAATCAAAATTGTTAcctgtgtaacaaaatttatatattttttt g" /listShort="S370, yhjG, yhjH" /GFF_Attribute="listLong" CDS 1122862..1124361 /gene="yhjG" /locus_tag="BSU_10500" /old_locus_tag="BSU10500" /EC_number="1.14.13.-" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 7678243, 15121720; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative aromatic compound monooxygenase/hydroxylase" /protein_id="NP_388931.1" /db_xref="EnsemblGenomes-Gn:BSU10500" /db_xref="EnsemblGenomes-Tr:CAB12890" /db_xref="GOA:O07561" /db_xref="InterPro:IPR002938" /db_xref="InterPro:IPR036188" /db_xref="SubtiList:BG13073" /db_xref="UniProtKB/Swiss-Prot:O07561" /translation="MMMKYEAVIIGGGPVGFMLASELAIAGVGTCVIERLEKPVPHSK ALTLHPRTLELLEMRGILERFVSKGSKIPTGHFSMLDTRLDFSGLDTSCPYTLLLPQS KTEKLLEDHARSLGTEVFRGAEALAVTQNGEAVQTIFKDRDGSVRTITSKFAVGADGA GSTVRKQAKIEFPGTDSTVTAALGDVVLLSPPPSGVLSLCTKEGGVMIVPLSPDRYRV VVISPYRTQTPKDVPVTEEELKADLLRICGTDFGLTDPSWMSRFGNAARQAKRYRDGR IFLAGDAAHIHFPAGGQGLNVGLQDAMNLGWKLAAAIKGSAPSWLLDSYHDERHPAAE GLLRNTEAQTKLIDFTQAGLHLRSMMSELLAFPDVNRYVAGQISALDVRYEADRTMPP NRLNGARLPDMKLILSDGNSERLYSFLQNGTFVLLSLRQEADDHIEVKGLRTVTASLA EPNEKLRNVHTILIRPDGHVAWAVDASAPDCSEVIQKGISRWFSVTSRV*" gene 1122862..1124361 /gene="yhjG" /locus_tag="BSU_10500" /old_locus_tag="BSU10500" promotor_-35 1124369..1124376 /Source="Nicolas_upshift_promotors" /id="U851" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.515484515484515" /psig=1 /xcortree=1955 /SigmaFactorBS="cagccgctggttttccgtcaccagccgagtataattcaattC GATTGTTtcatctgtaacaaAACGGTATGATAGAAGAAACaatcgaatgaaaaaggat g" /listShort="yhjH" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 1124388 /Source="Nicolas_upshifts" /id="U851" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.515484515484515" /psig=1 /xcortree=1955 /SigmaFactorBS="cagccgctggttttccgtcaccagccgagtataattcaattC GATTGTTtcatctgtaacaaAACGGTATGATAGAAGAAACaatcgaatgaaaaaggat g" /listShort="yhjH" /GFF_Attribute="listLong" promotor_-10 1124390..1124409 /Source="Nicolas_upshift_promotors" /id="U851" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.515484515484515" /psig=1 /xcortree=1955 /SigmaFactorBS="cagccgctggttttccgtcaccagccgagtataattcaattC GATTGTTtcatctgtaacaaAACGGTATGATAGAAGAAACaatcgaatgaaaaaggat g" /listShort="yhjH" /GFF_Attribute="listLong" /label="promotor_-10" CDS 1124438..1124965 /gene="yhjH" /locus_tag="BSU_10510" /old_locus_tag="BSU10510" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative transcriptional regulator" /protein_id="NP_388932.1" /db_xref="EnsemblGenomes-Gn:BSU10510" /db_xref="EnsemblGenomes-Tr:CAB12891" /db_xref="GOA:Q796S4" /db_xref="InterPro:IPR000835" /db_xref="InterPro:IPR023187" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG13074" /db_xref="UniProtKB/Swiss-Prot:Q796S4" /translation="MNTDHTKRNLFELYAELIHQQEKWEGLIKAFLSDELRKLDVEHG SKSQLTMTEIHVLSCVGDNEPINVTSIAEKMNTTKATVSRISTKLLGAGFLHRTQLSD NKKEVYFRLTPAGKKLHSLHKYYHQKAEQRFLSFFDRYTEEEILFAERLFRDLVTKWY PSSEEIEGGLPSIFK*" gene 1124438..1124965 /gene="yhjH" /locus_tag="BSU_10510" /old_locus_tag="BSU10510" downshifts 1124927 /Source="Nicolas_upshifts" /id="D574" /incds=0 /nref=8 /ntot=128 /MaxReadThrough="1.1509" /MaxDrop="3.41655" /score="11.3050978" /energy="-9.9" /TU="NA" /idTUdmin="U851" /TUdmin=8 /isTUend="TRUE" S_feature complement(1124979..1125122) /Source="Nicolas_S_feature" /locus_tag="new_1124979_1125122_c" /HighExp="B36, B60, T0.30H, LBGstat, T1.30H, T1.0H, LPhT, LBGtran, Diami, T-0.40H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.979" /TUlongSig="NA" /TUlongPSig="NA" /label="S371" downshifts complement(1125017) /Source="Nicolas_upshifts" /id="D575" /incds=0 /nref=4 /ntot=72 /MaxReadThrough="1.20458" /MaxDrop="5.06167" /score="27.254423" /energy="-9.9" /TU="NA" /idTUdmin="U855" /TUdmin=0 /isTUend="TRUE" CDS complement(1125123..1126328) /gene="glcP" /locus_tag="BSU_10520" /old_locus_tag="BSU10520" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:9457850, 15849754, 16850406, 17056753, 19087206" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9457850, 15849754, 16850406, 17056753, 19087206; Product type t : transporter" /codon_start=1 /transl_table=11 /product="glucose/mannose:H+ symporter (recent HGT island)" /protein_id="NP_388933.1" /db_xref="EnsemblGenomes-Gn:BSU10520" /db_xref="EnsemblGenomes-Tr:CAB12892" /db_xref="GOA:O07563" /db_xref="InterPro:IPR011701" /db_xref="InterPro:IPR020846" /db_xref="InterPro:IPR036259" /db_xref="SubtiList:BG13075" /db_xref="UniProtKB/Swiss-Prot:O07563" /translation="MLRGTYLFGYAFFFTVGIIHISTGSLTPFLLEAFNKTTDDISVI IFFQFTGFLSGVLIAPLMIKKYSHFRTLTLALTIMLVALSIFFLTKDWYYIIVMAFLL GYGAGTLETTVGSFVIANFESNAEKMSKLEVLFGLGALSFPLLINSFIDINNWFLPYY CIFTFLFVLFVGWLIFLSKNREYAKNANQQVTFPDGGAFQYFIGDRKKSKQLGFFVFF AFLYAGIETNFANFLPSIMINQDNEQISLISVSFFWVGIIIGRILIGFVSRRLDFSKY LLFSCSCLIVLLIAFSYISNPILQLSGTFLIGLSIAGIFPIALTLASIIIQKYVDEVT SLFIASASFGGAIISFLIGWSLNQDTILLTMGIFTTMAVILVGISVKIRRTKTEDPIS LENKASKTQ*" gene complement(1125123..1126328) /gene="glcP" /locus_tag="BSU_10520" /old_locus_tag="BSU10520" promotor_-35 1125818..1125823 /Source="Nicolas_upshift_promotors" /id="U852" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.995004995004995" /psig="0.995004995004995" /xcortree=1194 /SigmaFactorBS="tctcggttcttagacaagaaaattaaccaccctaCGAATAgg acgaataaaaaggtGAATATACAGTAATATGGTaaaaaccagttattgatatctatga a" /listShort="S372" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1125840..1125858 /Source="Nicolas_upshift_promotors" /id="U852" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.995004995004995" /psig="0.995004995004995" /xcortree=1194 /SigmaFactorBS="tctcggttcttagacaagaaaattaaccaccctaCGAATAgg acgaataaaaaggtGAATATACAGTAATATGGTaaaaaccagttattgatatctatga a" /listShort="S372" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 1125843..1126369 /Source="Nicolas_S_feature" /locus_tag="new_1125843_1126369" /HighExp="S4, S5, S6, S8, S7, S3, T5.0H, M9-stat, LBGstat, T4.0H" /AntisenseName="glcP" /AntisenseCor="-0.155079396671681" /AntisenseRegPval="-2" /CDS_PredictionProba="NA" /TUshortSig="SigEF" /TUshortPSig="0.995" /TUlongSig="NA" /TUlongPSig="NA" /label="S372" upshifts 1125844 /Source="Nicolas_upshifts" /id="U852" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.995004995004995" /psig="0.995004995004995" /xcortree=1194 /SigmaFactorBS="tctcggttcttagacaagaaaattaaccaccctaCGAATAgg acgaataaaaaggtGAATATACAGTAATATGGTaaaaaccagttattgatatctatga a" /listShort="S372" /GFF_Attribute="listLong" downshifts 1126327 /Source="Nicolas_upshifts" /id="D576" /incds=0 /nref=6 /ntot=59 /MaxReadThrough="2.40974" /MaxDrop="3.26024" /score="9.68585629" /energy="-9.4" /TU="NA" /idTUdmin="U852" /TUdmin=0 /isTUend="TRUE" CDS complement(1126400..1127452) /gene="ntdC" /locus_tag="BSU_10530" /old_locus_tag="BSU10530" /EC_number="1.1.1.-" /function="16.8: Protect" /function="16.5: Explore" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:14612444, 17056753, 23586652, 28353336" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 14612444, 17056753, 23586652, 28353336; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="biosynthesis of neotrehalosadiamine (3,3'-diamino-3,3'-dideoxy-alpha,beta-trehalose), glucose-6-P 3-dehydrogenase; kanosamine biosynthesis (recent HGT island)" /protein_id="NP_388934.2" /db_xref="EnsemblGenomes-Gn:BSU10530" /db_xref="EnsemblGenomes-Tr:CAB12893" /db_xref="GOA:O07564" /db_xref="InterPro:IPR000683" /db_xref="InterPro:IPR004104" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG13076" /db_xref="UniProtKB/Swiss-Prot:O07564" /translation="MKKIGIIGAGGIARAHATALSTIKNAELVGVYDINQQNAESFVK TFGGKSFENVDELIDASEGLIVASPNFCHKEHALQALGKHKHVLCEKPMAISLEEASI MKDTAERLSVRASMGFNYRYLSYVNILKSLIINNELGNILSIKVHFKKNSALRRKKFT WRDDANSKKTSGSLGDLGIHLIDMVWYLFESDFITESVRAKMNTNVKTKEDKQVLVDD YAEIYGQLKNKVFVNIITSKCSVPEDCGFSIEVVGHKKEFKYHTGNPHVYKLIDGLNV VDCPVPQSLLNDPPNEFYGWADSFRSELINWIASTQNDWVEIPSFSDGFRSQEVLEMF FEKDSNSQPMSVSAVN*" gene complement(1126400..1127452) /gene="ntdC" /locus_tag="BSU_10530" /old_locus_tag="BSU10530" CDS complement(1127466..1128314) /gene="ntdB" /locus_tag="BSU_10540" /old_locus_tag="BSU10540" /EC_number="3.-.-.-" /function="16.8: Protect" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:14612444, 17056753, 23586652" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 14612444, 17056753, 23586652; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="biosynthesis of neotrehalosadiamine (3,3'-diamino-3,3'-dideoxy-alpha, beta-trehalose);kanosamine-6-phosphate phosphatase (recent HGT island)" /protein_id="NP_388935.2" /db_xref="EnsemblGenomes-Gn:BSU10540" /db_xref="EnsemblGenomes-Tr:CAB12894" /db_xref="GOA:O07565" /db_xref="InterPro:IPR006379" /db_xref="InterPro:IPR006380" /db_xref="InterPro:IPR036412" /db_xref="PDB:3GYG" /db_xref="SubtiList:BG13077" /db_xref="UniProtKB/Swiss-Prot:O07565" /translation="MLLSKKSEYKTLSTVEHPQYIVFCDFDETYFPHTIDEQKQQDIY ELEDYLEQKSKDGELIIGWVTGSSIESILDKMGRGKFRYFPHFIASDLGTEITYFSEH NFGQQDNKWNSRINEGFSKEKVEKLVKQLHENHNILLNPQTQLGKSRYKHNFYYQEQD EINDKKNLLAIEKICEEYGVSVNINRCNPLAGDPEDSYDVDFIPIGTGKNEIVTFMLE KYNLNTERAIAFGDSGNDVRMLQTVGNGYLLKNATQEAKNLHNLITDSEYSKGITNTL KKLIGS*" gene complement(1127466..1128314) /gene="ntdB" /locus_tag="BSU_10540" /old_locus_tag="BSU10540" CDS complement(1128286..1129611) /gene="ntdA" /locus_tag="BSU_10550" /old_locus_tag="BSU10550" /EC_number="2.6.1.-" /function="16.5: Explore" /function="16.3: Control" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:14612444, 17056753, 19087206, 23586652, 24097983, 24509311, 28353336" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 14612444, 17056753, 19087206, 23586652, 24097983, 24509311, 28353336; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="biosynthesis of neotrehalosadiamine (3,3'-diamino-3,3'-dideoxy-alpha, beta-trehalose);3-oxo-glucose-6-phosphate:glutamate aminotransferase; kanosamine aminotransferase (recent HGT island)" /protein_id="NP_388936.1" /db_xref="EnsemblGenomes-Gn:BSU10550" /db_xref="EnsemblGenomes-Tr:CAB12895" /db_xref="GOA:O07566" /db_xref="InterPro:IPR000653" /db_xref="InterPro:IPR015421" /db_xref="InterPro:IPR015422" /db_xref="InterPro:IPR015424" /db_xref="PDB:4K2B" /db_xref="PDB:4K2I" /db_xref="PDB:4K2M" /db_xref="SubtiList:BG13078" /db_xref="UniProtKB/Swiss-Prot:O07566" /translation="MQKQVKISGKSKENMSLLKHLKGDVQGKELVIEDSIVNERWKQV LKEKIDIEHDLFNYQKNREISKVPFLPVDRLITNDEVEDILNTLTEVLPTGKFTSGPY LEQFEKVLSTYLHKRYVIATSSGTDAIMIGLLALGLNPGDEVIMPANSFSATENAVLA SGGVPIYVDINPQTFCIDPDKIEEAITPYTKFILPVHLYGKHSDMQHIRQIANRYKLK VIEDACQGIGLTDLGKYADITTLSFNPYKNFGVCGKAGAIATDNEELAKKCIQFSYHG FEVNVKNKKVINFGFNSKMDNLQAAIGLERMKYLSLNNFKRLFLADRYITQLAELQNK GYIELPELSEDHVWHLFPIKVRTEDRADIMTKLNEDFGVQTDVYYPILSHMQKTPLVQ DKYAGLQLVHTEKAHSQVLHLPLYPSFTLEEQDRVMEGLFHVIKQEIGV*" gene complement(1128286..1129611) /gene="ntdA" /locus_tag="BSU_10550" /old_locus_tag="BSU10550" promotor_-35 1128455..1128460 /Source="Nicolas_upshift_promotors" /id="U853" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=1031 /SigmaFactorBS="cctgcatacttgtcctgtactaaaggagtttttTGCATAtga gaaagtattggaTAATATACATCTGTTTGAAcaccaaaatcttcatttaatttagtca t" /listShort="S373, S374, yhjM" /listLong="S375" /label="promotor_-35" promotor_-10 1128476..1128494 /Source="Nicolas_upshift_promotors" /id="U853" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=1031 /SigmaFactorBS="cctgcatacttgtcctgtactaaaggagtttttTGCATAtga gaaagtattggaTAATATACATCTGTTTGAAcaccaaaatcttcatttaatttagtca t" /listShort="S373, S374, yhjM" /listLong="S375" /label="promotor_-10" S_feature 1128482..1129270 /Source="Nicolas_S_feature" /locus_tag="new_1128482_1129270" /HighExp="S4, S3, S5, S6, S7, T5.0H, M9-stat, S8, Pyr, G/S" /AntisenseName="ntdA" /AntisenseCor="-0.29559566742128002" /AntisenseRegPval="-6.1" /CDS_PredictionProba="NA" /TUshortSig="SigEF" /TUshortPSig="0.997" /TUlongSig="NA" /TUlongPSig="NA" /label="S373" upshifts 1128482 /Source="Nicolas_upshifts" /id="U853" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=1031 /SigmaFactorBS="cctgcatacttgtcctgtactaaaggagtttttTGCATAtga gaaagtattggaTAATATACATCTGTTTGAAcaccaaaatcttcatttaatttagtca t" /listShort="S373, S374, yhjM" /listLong="S375" promotor_-35 1129246..1129253 /Source="Nicolas_upshift_promotors" /id="U854" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.776223776223776" /psig="0.998001998001998" /xcortree=2928 /SigmaFactorBS="ataaacctatcataatagcatcggttccactgctGGTTGCAA ttacataccttttaTGTAAATATGTAGATAAAACtttttcgaattgctctaaataggg a" /listShort="S374, yhjM, S375" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1129268..1129287 /Source="Nicolas_upshift_promotors" /id="U854" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.776223776223776" /psig="0.998001998001998" /xcortree=2928 /SigmaFactorBS="ataaacctatcataatagcatcggttccactgctGGTTGCAA ttacataccttttaTGTAAATATGTAGATAAAACtttttcgaattgctctaaataggg a" /listShort="S374, yhjM, S375" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 1129272..1129714 /Source="Nicolas_S_feature" /locus_tag="new_1129272_1129714" /HighExp="T4.0H, T3.0H, T2.30H, HiOs, T3.30H, T2.0H, T5.0H, T1.30H, LoTm, T-1.10H" /AntisenseName="ntdA" /AntisenseCor="-0.101471720232752" /AntisenseRegPval="-1" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigEF" /TUshortPSig="0.998, 0.997" /TUlongSig="NA" /TUlongPSig="NA" /label="S374" upshifts 1129272 /Source="Nicolas_upshifts" /id="U854" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.776223776223776" /psig="0.998001998001998" /xcortree=2928 /SigmaFactorBS="ataaacctatcataatagcatcggttccactgctGGTTGCAA ttacataccttttaTGTAAATATGTAGATAAAACtttttcgaattgctctaaataggg a" /listShort="S374, yhjM, S375" /GFF_Attribute="listLong" promotor_-10 complement(1129646..1129665) /Source="Nicolas_upshift_promotors" /id="U855" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.849150849150849" /psig="0.97902097902098" /xcortree=1578 /SigmaFactorBS="gcatattttcccttccttaaaaaagttgttgaCATGTTACcg atttcagaaacTAGGATAAATTTGTAATAAAtttttagattataaaatcattggaggt a" /listShort="ntdA, ntdB, ntdC, glcP, S371" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1129658) /Source="Nicolas_upshifts" /id="U855" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.849150849150849" /psig="0.97902097902098" /xcortree=1578 /SigmaFactorBS="gcatattttcccttccttaaaaaagttgttgaCATGTTACcg atttcagaaacTAGGATAAATTTGTAATAAAtttttagattataaaatcattggaggt a" /listShort="ntdA, ntdB, ntdC, glcP, S371" /GFF_Attribute="listLong" promotor_-35 complement(1129679..1129686) /Source="Nicolas_upshift_promotors" /id="U855" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.849150849150849" /psig="0.97902097902098" /xcortree=1578 /SigmaFactorBS="gcatattttcccttccttaaaaaagttgttgaCATGTTACcg atttcagaaacTAGGATAAATTTGTAATAAAtttttagattataaaatcattggaggt a" /listShort="ntdA, ntdB, ntdC, glcP, S371" /GFF_Attribute="listLong" /label="promotor_-35" CDS 1129715..1130704 /gene="ntdR" /locus_tag="BSU_10560" /old_locus_tag="BSU10560" /experiment="publication(s) with functional evidences, PMID:14612444, 17056753" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 14612444, 17056753; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator of the ntd operon (NtdR-NTD) (recent HGT island)" /protein_id="NP_388937.1" /db_xref="EnsemblGenomes-Gn:BSU10560" /db_xref="EnsemblGenomes-Tr:CAB12896" /db_xref="GOA:O07567" /db_xref="InterPro:IPR000843" /db_xref="InterPro:IPR010982" /db_xref="InterPro:IPR028082" /db_xref="InterPro:IPR036388" /db_xref="SubtiList:BG13079" /db_xref="UniProtKB/Swiss-Prot:O07567" /translation="MPTIDEIAKLCNVSKTTVSRVLNNHPYVSKEKRDMILKAINELD YTPNYLARNFRRNKTQTIALSVPSIDHPFFAQLIKGVSHEVLFKNYKVIVFQTFYDKQ TELELLELLKHKEVDGIILGTLENEWDQISPFLKYGPILLCNEYHHSADITIIGYDEF EAAYMGVVHLIERGHKKIGFCFDTPYSEAQCQRKEGYLKALQDYNLHHRSEWIFGEMF NIEDGFRVFHKIKDLKDRPSAIFTGNDQVAAGIIKQAMKNGFKVPEDLAVIGFDNQLI CQVVTPTITTIDIPVIELGQQAVLKIIESISGNASLNRRIIKLPTKLIIREST*" gene 1129715..1130704 /gene="ntdR" /locus_tag="BSU_10560" /old_locus_tag="BSU10560" S_feature 1130705..1131082 /Source="Nicolas_S_feature" /locus_tag="new_1130705_1131082" /HighExp="T4.0H, T5.0H, T3.30H, T2.0H, HiOs, T2.30H, T3.0H, LoTm, T1.30H, Pyr" /AntisenseName="yhjN" /AntisenseCor="-5.0383887616073E-2" /AntisenseRegPval="-0.4" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.998" /TUlongSig="SigEF" /TUlongPSig="0.997" /label="S375" S_feature complement(1130759..1130917) /Source="Nicolas_S_feature" /locus_tag="new_1130759_1130917_c" /HighExp="B60, Sw, Cold, B36, BI, GM 15, GM 10, C30, GM 25, GM 60" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.99" /TUlongSig="NA" /TUlongPSig="NA" /label="S376" downshifts complement(1130802) /Source="Nicolas_upshifts" /id="D577" /incds=0 /nref=25 /ntot=169 /MaxReadThrough="3.07371" /MaxDrop="4.24831" /score="-1.9470655" /energy="-7.1" /TU="U856" /idTUdmin="U856" /TUdmin="-66" /isTUend="FALSE" CDS complement(1130918..1132072) /gene="yhjN" /locus_tag="BSU_10570" /old_locus_tag="BSU10570" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406, 22720735; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative integral inner membrane protein (recentHGT island)" /protein_id="NP_388938.1" /db_xref="EnsemblGenomes-Gn:BSU10570" /db_xref="EnsemblGenomes-Tr:CAB12897" /db_xref="GOA:O07568" /db_xref="InterPro:IPR007820" /db_xref="InterPro:IPR017516" /db_xref="SubtiList:BG13080" /db_xref="UniProtKB/Swiss-Prot:O07568" /translation="MKKDENLLKDLWFIAISAAGGFILSLTGISIGWMIGTLIVACCL AMIRPAWLMMAPDQKGINRRWLALGQMILGIELGQKLNLSVLSVLKDHWFSVGVMLIL SILLAMLSGYVLWRFSKTDMMTSFVGTAPGGLSAMPSIAQEVGANTAIVSLVQMMRVL LVVLSIPFLVILIYTKQDRTASAAAETISSATTDFRLAPVLWTVILILAAWGACKAAK FLKFPAPWLLGSMLGVAIVHVGGAAVTGHDMTAWWLSQANHVSQVFLGATIGSKMYKS MFAGVTRIIIVGFVSSVGLIAAMFLSAVIVSELTGISLITSVLAFAPGGIAEMATTSV TLHADSTFVVAVQVIRVILVIALLPPFYRLLHHLHGEKKDKKSSISGSSA*" gene complement(1130918..1132072) /gene="yhjN" /locus_tag="BSU_10570" /old_locus_tag="BSU10570" S_feature complement(1132073..1132144) /Source="Nicolas_S_feature" /locus_tag="new_1132073_1132144_c" /HighExp="Cold, GM 15, GM 10, dia15, BC, BI, Salt, B60, Sw, GM 90" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.99" /TUlongSig="NA" /TUlongPSig="NA" /label="S377" promotor_-10 complement(1132127..1132146) /Source="Nicolas_upshift_promotors" /id="U856" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.414585414585415" /psig="0.99000999000999" /xcortree=2773 /SigmaFactorBS="cataagaaaagtgaatcgcttatagaaaataattcataATTT CTttatcaacaaaaaTATACTATAGTAATAAATACattcactacgtgaacaattggag t" /listShort="S377, yhjN, S376" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1132143) /Source="Nicolas_upshifts" /id="U856" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.414585414585415" /psig="0.99000999000999" /xcortree=2773 /SigmaFactorBS="cataagaaaagtgaatcgcttatagaaaataattcataATTT CTttatcaacaaaaaTATACTATAGTAATAAATACattcactacgtgaacaattggag t" /listShort="S377, yhjN, S376" /GFF_Attribute="listLong" promotor_-35 complement(1132160..1132165) /Source="Nicolas_upshift_promotors" /id="U856" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.414585414585415" /psig="0.99000999000999" /xcortree=2773 /SigmaFactorBS="cataagaaaagtgaatcgcttatagaaaataattcataATTT CTttatcaacaaaaaTATACTATAGTAATAAATACattcactacgtgaacaattggag t" /listShort="S377, yhjN, S376" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(1132179..1133384) /gene="yhjO" /locus_tag="BSU_10580" /old_locus_tag="BSU10580" /function="16.1: Circulate" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative permease (recent HGT island)" /protein_id="NP_388939.1" /db_xref="EnsemblGenomes-Gn:BSU10580" /db_xref="EnsemblGenomes-Tr:CAB12898" /db_xref="GOA:O07569" /db_xref="InterPro:IPR011701" /db_xref="InterPro:IPR020846" /db_xref="InterPro:IPR036259" /db_xref="SubtiList:BG13081" /db_xref="UniProtKB/Swiss-Prot:O07569" /translation="MLTSFHSIKSRYTAPVRLRFFGELLTSLTGAMMGPFMVLYLHEQ LNGSIMMPMLIISLQPFADIFLTLAAGRVTDRLGRRTAILTALLLQSAAMTGFVFAEH AYVFAILYVMNGIGRSLYIPASRAQIAESTPESRRSEVFAVINAIYSTGLTAGPLVGM LLYNHNPVWIFALDAAALFIYFLIAALKLPETKPLHPAVTPKMSASFTIYRPVLLLLL LSLPISMLYAQTETTYRLFSKNMFSDYLSMLTIYSAAKALFSCVLQVPLVKGTEKLSM KTILFITYICYSLAAAGFACSTSLTMLLVTAAVMTVGESIGLTHIQTFISKLAPPHLL GRFYAVYGLHWDISRSIGPLAGGLILTSFGGEVIFYALAVCLLTAGLSLTYTIEKLEH KVIRKVNRL*" gene complement(1132179..1133384) /gene="yhjO" /locus_tag="BSU_10580" /old_locus_tag="BSU10580" misc_feature 1133405..1133424 /Source="Nicolas_upshift_promotors" /id="U857" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.699300699300699" /psig="0.999000999001" /xcortree=2118 /SigmaFactorBS="tatctcgattttatagagtgaaaactggtcaacatgtgatcg ccgcctttcgctgTTTGATATAGTAGTAGTGTAtagaaggggcggcggcccaaaaagt g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 1133410 /Source="Nicolas_upshifts" /id="U857" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.699300699300699" /psig="0.999000999001" /xcortree=2118 /SigmaFactorBS="tatctcgattttatagagtgaaaactggtcaacatgtgatcg ccgcctttcgctgTTTGATATAGTAGTAGTGTAtagaaggggcggcggcccaaaaagt g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" CDS 1133498..1135225 /gene="yhjP" /locus_tag="BSU_10590" /old_locus_tag="BSU10590" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative transcription factor" /protein_id="NP_388940.1" /db_xref="EnsemblGenomes-Gn:BSU10590" /db_xref="EnsemblGenomes-Tr:CAB12899" /db_xref="GOA:O07570" /db_xref="InterPro:IPR000914" /db_xref="InterPro:IPR025370" /db_xref="InterPro:IPR030678" /db_xref="InterPro:IPR036388" /db_xref="SubtiList:BG13082" /db_xref="UniProtKB/Swiss-Prot:O07570" /translation="MKLIEHYVALVKTGCAEYGQMNEMTLTEIADCLFCTERNAKLIL HKLENSNWIIRESGAGRGRKSKIAFLRRPEELLLQTAKEYTMSGKLKKAKELLQQYQS AFPGLQNEYNMWLSEVFGFVTETGENGAKDVLRLFITPESVSSLDPCQIFLRSEGHFV KQIFDTLFTFDSDMQEPKPHLVHGWEEVGKKQWRFFLRKGVLFHNGQPLTSRDVAFTF QRFLELADNPYKWLLHGVKQVLEKGPYCVELILDKPNALLPYALCDERLSILPAEQGG GKNGTGPFQMNQQHSGMLVLEANERYFKGRPYLDRVEFVFSEQAGEMNGFTIQEKQTC PEQQTVFDERHVQYLSLNLKKKGPLQHRSFRKALRLLISSERLVREAGGHRRIPVTSF LHPSPFEWEGVSPSELLKKSGYEGETIVLYTFSETDHREDAEWIQNICAQHGIRLTLQ FCDAADLRRPEIVQMADIIHDSATFYQDSEFGFLHLLLSENSFLYQHLSEKLTQICSG MTERMFSMPDRCSRINILRDIDRQMIQELNAIPLYQNVLQVTSSKNVKGLVLDEEGWI DLYSVWLSK*" gene 1133498..1135225 /gene="yhjP" /locus_tag="BSU_10590" /old_locus_tag="BSU10590" promotor_-35 1134811..1134818 /Source="Nicolas_upshift_promotors" /id="U858" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.531468531468531" /psig="0.802197802197802" /xcortree=1827 /SigmaFactorBS="atcatcgtgaggacgccgaatggattcaaaaTATTTGCGccc agcacggtatcAGGCTTACACTTCAATTCTGtgatgctgctgatctgcgacggccgga a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1134833..1134852 /Source="Nicolas_upshift_promotors" /id="U858" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.531468531468531" /psig="0.802197802197802" /xcortree=1827 /SigmaFactorBS="atcatcgtgaggacgccgaatggattcaaaaTATTTGCGccc agcacggtatcAGGCTTACACTTCAATTCTGtgatgctgctgatctgcgacggccgga a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1134840 /Source="Nicolas_upshifts" /id="U858" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.531468531468531" /psig="0.802197802197802" /xcortree=1827 /SigmaFactorBS="atcatcgtgaggacgccgaatggattcaaaaTATTTGCGccc agcacggtatcAGGCTTACACTTCAATTCTGtgatgctgctgatctgcgacggccgga a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" CDS complement(1135255..1135581) /gene="yhjQ" /locus_tag="BSU_10600" /old_locus_tag="BSU10600" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 12625841; Product type c: carrier" /codon_start=1 /transl_table=11 /product="putative metal-chelating cysteine-rich protein of unknown function" /protein_id="NP_388941.1" /db_xref="EnsemblGenomes-Gn:BSU10600" /db_xref="EnsemblGenomes-Tr:CAB12900" /db_xref="InterPro:IPR005560" /db_xref="PDB:5FIG" /db_xref="SubtiList:BG13083" /db_xref="UniProtKB/Swiss-Prot:O07571" /translation="MEQYSEACIEACIDCMKACNHCFTKCLEESVQHHLSGCIRLDRE CADICALAVKAMQTDSPFMKEICALCADICEACGTECGKHDHDHCQACAKACFTCAEQ CRSMAA*" gene complement(1135255..1135581) /gene="yhjQ" /locus_tag="BSU_10600" /old_locus_tag="BSU10600" CDS complement(1135699..1136136) /gene="yhjR" /locus_tag="BSU_10610" /old_locus_tag="BSU10610" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 22078549, 22882546; Product type c: carrier" /codon_start=1 /transl_table=11 /product="putative electron carrier protein (putative sporulation gene)" /protein_id="NP_388942.1" /db_xref="EnsemblGenomes-Gn:BSU10610" /db_xref="EnsemblGenomes-Tr:CAB12901" /db_xref="GOA:O07572" /db_xref="InterPro:IPR003251" /db_xref="InterPro:IPR009078" /db_xref="InterPro:IPR012347" /db_xref="SubtiList:BG13084" /db_xref="UniProtKB/Swiss-Prot:O07572" /translation="MHYSYYPYPVPYREDPVLIRNLQKAINGEFSAIQCYRKLAELAH SDEVRKQIEEIRRDEIRHLREFSTLYGSITGKHIMPKQTEECPDNFTRGLDAAFKDEQ ETVDFYLRAAEETSNLKAKGVFTRAARDEQNHAVWFLYYLMER*" gene complement(1135699..1136136) /gene="yhjR" /locus_tag="BSU_10610" /old_locus_tag="BSU10610" downshifts complement(1135708) /Source="Nicolas_upshifts" /id="D578" /incds=0 /nref=1 /ntot=10 /MaxReadThrough="3.72767" /MaxDrop="3.86885" /score="16.2430017" /energy="-11.5" /TU="U859" /idTUdmin="U859" /TUdmin="-440" /isTUend="FALSE" promotor_-10 complement(1136167..1136186) /Source="Nicolas_upshift_promotors" /id="U859" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1267 /SigmaFactorBS="tggtaaaaacggccttttcacatataaaaagctgattatCTC CGCACATctctccctgcccAACATATACTTTTACAGAAGcccaattcctaagaatgga g" /listShort="yhjR, yhjQ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1136187) /Source="Nicolas_upshifts" /id="U859" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1267 /SigmaFactorBS="tggtaaaaacggccttttcacatataaaaagctgattatCTC CGCACATctctccctgcccAACATATACTTTTACAGAAGcccaattcctaagaatgga g" /listShort="yhjR, yhjQ" /GFF_Attribute="listLong" promotor_-35 complement(1136199..1136208) /Source="Nicolas_upshift_promotors" /id="U859" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1267 /SigmaFactorBS="tggtaaaaacggccttttcacatataaaaagctgattatCTC CGCACATctctccctgcccAACATATACTTTTACAGAAGcccaattcctaagaatgga g" /listShort="yhjR, yhjQ" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1136256..1136263 /Source="Nicolas_upshift_promotors" /id="U860" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.875124875124875" /psig=1 /xcortree=1809 /SigmaFactorBS="gaaaaggccgtttttaccaatagatcaGATTGGTCattttcg tcaacaTTCGATAAAATATAGAGAGAtaaaaagagaggggtcttctaatttgggagca g" /listShort="addB, addA, S378, sbcD, sbcC, yisB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1136277..1136296 /Source="Nicolas_upshift_promotors" /id="U860" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.875124875124875" /psig=1 /xcortree=1809 /SigmaFactorBS="gaaaaggccgtttttaccaatagatcaGATTGGTCattttcg tcaacaTTCGATAAAATATAGAGAGAtaaaaagagaggggtcttctaatttgggagca g" /listShort="addB, addA, S378, sbcD, sbcC, yisB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1136289 /Source="Nicolas_upshifts" /id="U860" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.875124875124875" /psig=1 /xcortree=1809 /SigmaFactorBS="gaaaaggccgtttttaccaatagatcaGATTGGTCattttcg tcaacaTTCGATAAAATATAGAGAGAtaaaaagagaggggtcttctaatttgggagca g" /listShort="addB, addA, S378, sbcD, sbcC, yisB" /GFF_Attribute="listLong" CDS 1136320..1139820 /gene="addB" /locus_tag="BSU_10620" /old_locus_tag="BSU10620" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:7746142, 8387145, 8510642, 8752323, 11544244, 16385024, 16780573, 19542287, 21071401, 22307084, 24670664, 26762979" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7746142, 8387145, 8510642, 8752323, 11544244, 16385024, 16780573, 19542287, 21071401, 22307084, 24670664, 26762979; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="ATP-dependent deoxyribonuclease (subunit B)" /protein_id="NP_388943.2" /db_xref="EnsemblGenomes-Gn:BSU10620" /db_xref="EnsemblGenomes-Tr:CAB12902" /db_xref="GOA:P23477" /db_xref="InterPro:IPR014016" /db_xref="InterPro:IPR014017" /db_xref="InterPro:IPR014140" /db_xref="InterPro:IPR027417" /db_xref="PDB:3U44" /db_xref="PDB:3U4Q" /db_xref="PDB:4CEH" /db_xref="PDB:4CEI" /db_xref="PDB:4CEJ" /db_xref="SubtiList:BG10465" /db_xref="UniProtKB/Swiss-Prot:P23477" /translation="MGAEFLVGRSGSGKTKLIINSIQDELRRAPFGKPIIFLVPDQMT FLMEYELAKTPDMGGMIRAQVFSFSRLAWRVLQHTGGMSRPFLTSTGVQMLLRKLIEE HKQEFKVYQKASDKSGFTAQVERMLTEFKRYCLEPEDIRRMAESGTASEYRGERVLSE KLHDLSILYQQMEKSLADQYLHSEDYLTLLAEHIPLAEDIKGAHIYVDGFYQFTPQEF RVLEQLMVHAEHITFSLTADKPSYEREPHELELFRMTGKTYYRLHQKAKELNLDITYK ELSGTERHTKTPELAHLEAQYEARPAIPYAEKQEALTVMQAANRRAELEGIAREIHAL VREKGYRYKDVAILARQPEDYKDMVKEVFADYEIPYFIDGKASMLNHPLIEFIRSSLD VLKGNWRYEAVFRCVKTELLFPLNEPKAKVREQVDQLENYCIAYGIKGDRWTKGDRFQ YRRFVSLDDDFAQTDQEIEMENMLNDTRDWIVPPLFQLQKRMKKAKTVQEKAEALYRY LEETDVPLKLDQERQRAEDDGRIIEAQQHQQAWDAVIQLLEEFVEMMGDDEISLDLFQ QMIEAGAESLTFSLIPPALDQVFVGNMDLSRMYGTSCTFVLGANDGVLPARPDENGVL SDDDREWLKTIGVELSSGGRERLLDEHFLIYMAFSSPSDRLYVSYPIADAEGKTLLPS MIVKRLEELFPHHKERLLTNEPEQVSDEEQLMYVVNKSVAQSFTASQLRLWTREYDIS DVWWSTYNVLMSEQDRLQSKKLFSSLFFRNEVKQLERSVSRQLYGERIQGSVSRMETF NACPFSHFASHGLHLKERQFFKLEAPDIGQLFHSSLKLISDRLREQKLDWRDLTKEQC ELFSYDAVERLAPKLQKEILLSSNRHYYVKEKLQKIVTRVSGILSEHAKASGFVPIGL ELGFGGKGPLPPLTFQLKNGCTMELVGRIDRVDKAESSKGLLLRIVDYKSSDKGLDLA EVYYGLALQMLTYLDLSITHSADWLGMRATPAGVLYFHIHDPMIQSNLPLGLDEIEQE IFKKFKMKGLLLGDQEVVRLMDTTLQEGRSNIINAGLKKDGSLRSDSAAVGEKEFDLL TKHVRRTFQEAGEQITDGRVSIEPYKMKNKTPCTYCAFKSVCQFDESLEENEYRPLKA EKDKTILEWIKKEADGNEHS*" gene 1136320..1139820 /gene="addB" /locus_tag="BSU_10620" /old_locus_tag="BSU10620" CDS 1139807..1143505 /gene="addA" /locus_tag="BSU_10630" /old_locus_tag="BSU10630" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:7746142, 8387145, 8510642, 8752323, 11544244, 16385024, 16780573, 19542287, 21071401, 22307084, 24670664, 26762979" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7746142, 8387145, 8510642, 8752323, 11544244, 16385024, 16780573, 19542287, 21071401, 22307084, 24670664, 26762979; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="ATP-dependent deoxyribonuclease (subunit A)" /protein_id="NP_388944.2" /db_xref="EnsemblGenomes-Gn:BSU10630" /db_xref="EnsemblGenomes-Tr:CAB12903" /db_xref="GOA:P23478" /db_xref="InterPro:IPR000212" /db_xref="InterPro:IPR011335" /db_xref="InterPro:IPR011604" /db_xref="InterPro:IPR014016" /db_xref="InterPro:IPR014017" /db_xref="InterPro:IPR014152" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR034739" /db_xref="PDB:3U44" /db_xref="PDB:3U4Q" /db_xref="PDB:4CEH" /db_xref="PDB:4CEI" /db_xref="PDB:4CEJ" /db_xref="SubtiList:BG10466" /db_xref="UniProtKB/Swiss-Prot:P23478" /translation="MNIPKPADSTWTDDQWNAIVSTGQDILVAAAAGSGKTAVLVERM IRKITAEENPIDVDRLLVVTFTNASAAEMKHRIAEALEKELVQRPGSLHIRRQLSLLN RASISTLHSFCLQVLKKYYYLIDLDPGFRIADQTEGELIGDEVLDELFEDEYAKGEKA FFELVDRYTTDRHDLDLQFLVKQVYEYSRSHPNPEAWLESFVHLYDVSEKSAIEELPF YQYVKEDIAMVLNGAKEKLLRALELTKAPGGPAPRADNFLDDLAQIDELIQHQDDFSE LYKRVPAVSFKRAKAVKGDEFDPALLDEATDLRNGAKKLLEKLKTDYFTRSPEQHLKS LAEMKPVIETLVQLVISYGKRFEAAKQEKSIIDFSDLEHYCLAILTAENDKGEREPSE AARFYQEQFHEVLVDEYQDTNLVQESILQLVTSGPEETGNLFMVGDVKQSIYRFRLAE PLLFLSKYKRFTESGEGTGRKIDLNKNFRSRADILDSTNFLFKQLMGGKIGEVDYDEQ AELKLGAAYPDNDETETELLLIDNAEDTDASEEAEELETVQFEAKAIAKEIRKLISSP FKVYDGKKKTHRNIQYRDIVILLRSMPWAPQIMEELRAQGIPVYANLTSGYFEAVEVA VALSVLKVIDNPYQDIPLASVLRSPIVGADENELSLIRLENKKAPYYEAMKDYLAAGD RSDELYQKLNTFYGHLQKWRAFSKNHSVSELIWEVYRDTKYMDYVGGMPGGKQRQANL RVLYDRARQYESTAFRGLFRFLRFIERMQERGDDLGTARALSEQEDVVRLMTIHSSKG LEFPVVFVAGLGRNFNMMDLNKSYLLDKELGFGTKYIHPQLRISYPTLPLIAMKKKMR RELLSEELRVLYVALTRAKEKLFLIGSCKDHQKQLAKWQASASQTDWLLPEFDRYQAR TYLDFIGPALARHRDLGDLAGVPAHADISGHPARFAVQMIHSYDLLDDDLEERMEEKS ERLEAIRRGEPVPGSFAFDEKAREQLSWTYPHQEVTQIRTKQSVSEIKRKREYEDEYS GRAPVKPADGSILYRRPAFMMKKGLTAAEKGTAMHTVMQHIPLSHVPSIEEAEQTVHR LYEKELLTEEQKDAIDIEEIVQFFHTEIGGQLIGAKWKDREIPFSLALPAKEIYPDAH EADEPLLVQGIIDCLYETEDGLYLLDYKSDRIEGKFQHGFEGAAPILKKRYETQIQLY TKAVEQIAKTKVKGCALYFFDGGHILTL*" gene 1139807..1143505 /gene="addA" /locus_tag="BSU_10630" /old_locus_tag="BSU10630" S_feature 1143506..1143576 /Source="Nicolas_S_feature" /locus_tag="new_1143506_1143576" /HighExp="H2O2, C90, Heat, LBGtran, dia15, HiTm, Diami, C30, Lbtran, G135" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S378" CDS 1143577..1144752 /gene="sbcD" /locus_tag="BSU_10640" /old_locus_tag="BSU10640" /function="16.6: Maintain" /function="16.9: Replicate" /experiment="publication(s) with functional evidences, PMID:7968921, 8493111, 16780573" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7968921, 8493111, 16780573; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="DNA repair exonuclease" /protein_id="NP_388945.3" /db_xref="EnsemblGenomes-Gn:BSU10640" /db_xref="EnsemblGenomes-Tr:CAB12904" /db_xref="GOA:P23479" /db_xref="InterPro:IPR004593" /db_xref="InterPro:IPR004843" /db_xref="InterPro:IPR026843" /db_xref="InterPro:IPR029052" /db_xref="SubtiList:BG10467" /db_xref="UniProtKB/Swiss-Prot:P23479" /translation="MRILHTADWHLGKTLEGRSRLSEQADVLDELNTIVKDEQIDAIV MAGDAFDTVNPPALAEQLFYESLSALSDRGKRPIVVIAGNHDNPDRLSAASPLTHENG IHLIGYPTTEPIHIEVPSAGELLAVGALAYPSEARLNEVLSDTFDEKLLRDHYDVKIR QAFEHMTSRFRTDAVKIAASHIYVAGGNQTDSERPIEVGGAYTVAAESLPADAAYVAL GHLHRPQTIKRARTLARYSGSPLAYSFSEAGYAKSVTIVDAKPGEEATWQEVLLSSGK PLVKWKAANGLSEVYSWLDEGRDQNAWIDLEIRVADQLSLEEIHRLRKAHPGFIHIRP VFEEQNKDRERIEVKHVSIEDRFKKFYEKQTGGAVPDEEMVKLFLELASGVEEEDAK* " gene 1143577..1144752 /gene="sbcD" /locus_tag="BSU_10640" /old_locus_tag="BSU10640" CDS 1144749..1148141 /gene="sbcC" /locus_tag="BSU_10650" /old_locus_tag="BSU10650" /function="16.9: Replicate" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:16780573, 19906728" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16780573, 19906728; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="DNA ATP-dependent repair enzyme" /protein_id="NP_388946.2" /db_xref="EnsemblGenomes-Gn:BSU10650" /db_xref="EnsemblGenomes-Tr:CAB12905" /db_xref="GOA:O06714" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG13088" /db_xref="UniProtKB/Swiss-Prot:O06714" /translation="MKPIALSIKGLHSFREEQTIDFEGLSGAGVFGIFGPTGSGKSSI LDAMTLALYGKVERAANNTHGILNHAEDTLSVSFTFALQTNHQISYKVERVFKRTDEM KVKTALCRFIEIKDEHTVLADKASEVNKRVEELLGLTIDDFTRAVVLPQGKFAEFLSL KGAERRHMLQRLFNLEQYGDRLVKKLRRQAQEANARKNEMLAEQSGLGEASSEAVEQA EKVLEQAEARLEAMRKNRDQAKERFTEHQEIWNVQKEKSTYEEEEKRLAEEQPHIDSM QKRLLEAETAAALKPYADRYAEAIQHEEQAEKEQTLAQKDLADRTAFFQQKHEEYEAW RQHKSEKEPELLAKQEQLSRLQEIEIKLSEAKQEEERKKADLRQKEEALQSVMNELET VTDRLTRGQNRQTELKQQLKSLQVTSDERKSCQQAAEMALRIRQTEEQIKKEKKRSEE LNLVLQKMNEEKNTLVQKTEAEENNIIQAYEAVQTVYHLVCETERSLTRMTEEARKSQ HTLHLQREKARVALLTKELAQKLTAGKPCPVCGSTDHDPSASVHETYEADSHLEEDIK RTDVLLTEAAALSQEILSAKIMLEEQSARFIEQCPFLQTIQAQNLEAAASFEHQPVYE AFETAKFEWKRIKQDILSVKTRMAQMIGAYQESLKKAEQLNEKIGFEKREADRIESII SELQSSMDSSLNMFKEAFQNQSVDEAEKWQQAIEEKDRAAEECEKRIEKSIAFLAEHE AQKEKLRESGHRLEREKLELHYAAERIKSVIADYEHELGDYAKGDSIQIKLRSVQQDL KLLKEKEQSLYEELQSAQMKLNQAKSRASASELTLQEAKGRLEKAKAAWLEHTKNTSI TRTEEVEQSLIPADELEKMKTGIDQFMDKLKQNAANLKRVAEILAGRALSESEWNETV AALQEAEDAFGAAIEEKGAAAKALAVIRDHHKRFNEIEAELKKWQMHIDRLDKLQAVF KGNTFVEFLAEEQLESVARDASARLSMLTRQRYAIEVDSEGGFVMRDDANGGVRRPVS SLSGGETFLTSLSLALALSAQIQLRGEYPLQFFFLDEGFGTLDQDLLDTVVTALEKLQ SDNLAVGVISHVQELRARLPKKLIVHPAEPSGRGTRVSLELM*" gene 1144749..1148141 /gene="sbcC" /locus_tag="BSU_10650" /old_locus_tag="BSU10650" promotor_-35 1147396..1147402 /Source="Nicolas_upshift_promotors" /id="U861" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.99000999000999" /psig="0.99000999000999" /xcortree=813 /SigmaFactorBS="tgaaaagatgaaaaccggcatagaccagtttaTGGATAAact gaagcaaaatgCTGCAAACTTAAaacgagtagcagagatacttgccggcagagcatta t" /listShort="yisB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1147417..1147428 /Source="Nicolas_upshift_promotors" /id="U861" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.99000999000999" /psig="0.99000999000999" /xcortree=813 /SigmaFactorBS="tgaaaagatgaaaaccggcatagaccagtttaTGGATAAact gaagcaaaatgCTGCAAACTTAAaacgagtagcagagatacttgccggcagagcatta t" /listShort="yisB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1147424 /Source="Nicolas_upshifts" /id="U861" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.99000999000999" /psig="0.99000999000999" /xcortree=813 /SigmaFactorBS="tgaaaagatgaaaaccggcatagaccagtttaTGGATAAact gaagcaaaatgCTGCAAACTTAAaacgagtagcagagatacttgccggcagagcatta t" /listShort="yisB" /GFF_Attribute="listLong" S_feature complement(1147493..1148466) /Source="Nicolas_S_feature" /locus_tag="new_1147493_1148466_c" /HighExp="S6, S8, S7, BT, C30, B36, S5, C90, Pyr, B60" /AntisenseName="yisB" /AntisenseCor="0.19649597897587401" /AntisenseRegPval="-2.9" /CDS_PredictionProba="NA" /TUshortSig="SigK" /TUshortPSig=1 /TUlongSig="SigK" /TUlongPSig="0.992" /label="S379" CDS 1148155..1148457 /gene="hlpB" /locus_tag="BSU_10660" /old_locus_tag="BSU10660" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:16780573, 22984257" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16780573, 22984257; Product type ph: phenotype" /codon_start=1 /transl_table=11 /product="HNH nuclease-like essential for DNA repair" /protein_id="NP_388947.1" /db_xref="EnsemblGenomes-Gn:BSU10660" /db_xref="EnsemblGenomes-Tr:CAB12906" /db_xref="SubtiList:BG13089" /db_xref="UniProtKB/Swiss-Prot:O06715" /translation="MAKQIAGICELCGRSDVQLTEHHLTPKEEGGTFLPTAMLCIPCH KQIHALYTNQELAVRLNGMAELRSDPELARFVKWIRKQPPEKLIKTKKSNERKKKK*" gene 1148155..1148457 /gene="hlpB" /locus_tag="BSU_10660" /old_locus_tag="BSU10660" downshifts 1148437 /Source="Nicolas_upshifts" /id="D579" /incds=0 /nref=230 /ntot=269 /MaxReadThrough="1.42126" /MaxDrop="6.71114" /score="0.317490594" /energy="-14.3" /TU="NA" /idTUdmin="U861" /TUdmin=1 /isTUend="TRUE" CDS complement(1148494..1148712) /gene="gerPF" /locus_tag="BSU_10670" /old_locus_tag="BSU10670" /function="16.5: Explore" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:10715007, 20161744" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10715007, 20161744; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="spore germination protein" /protein_id="NP_388948.2" /db_xref="EnsemblGenomes-Gn:BSU10670" /db_xref="EnsemblGenomes-Tr:CAB12907" /db_xref="GOA:O06716" /db_xref="InterPro:IPR019618" /db_xref="SubtiList:BG13090" /db_xref="UniProtKB/Swiss-Prot:O06716" /translation="MPAIVGPIAINSISGGVVNFGDSFYLSPKSSSKSALGSGAGNTG DFLLLNNAVNATNYIDPDVNDQDMVGNG*" gene complement(1148494..1148712) /gene="gerPF" /locus_tag="BSU_10670" /old_locus_tag="BSU10670" downshifts complement(1148511) /Source="Nicolas_upshifts" /id="D580" /incds=0 /nref=40 /ntot=66 /MaxReadThrough="3.93344" /MaxDrop="5.39228" /score="13.5435041" /energy="-15.3" /TU="U863" /idTUdmin="U863" /TUdmin="-989" /isTUend="FALSE" CDS complement(1148744..1149145) /gene="gerPE" /locus_tag="BSU_10680" /old_locus_tag="BSU10680" /function="16.5: Explore" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:10715007" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10715007; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="spore germination protein" /protein_id="NP_388949.1" /db_xref="EnsemblGenomes-Gn:BSU10680" /db_xref="EnsemblGenomes-Tr:CAB12908" /db_xref="GOA:O06717" /db_xref="InterPro:IPR024496" /db_xref="SubtiList:BG13091" /db_xref="UniProtKB/Swiss-Prot:O06717" /translation="MLKRISRIRLVKFNSLGIASVFQVGDTNEIDMSVKVFAVQRSLS TFYHNEGSFNKKEYQIFQQQAVKPLPETGVQSAFCHEVPAIYVRSIKIQGVSASSVLH AGSASLIRGDARLKHIRQIQSPRSQSPAKNI*" gene complement(1148744..1149145) /gene="gerPE" /locus_tag="BSU_10680" /old_locus_tag="BSU10680" CDS complement(1149145..1149321) /gene="gerPD" /locus_tag="BSU_10690" /old_locus_tag="BSU10690" /function="16.5: Explore" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:10715007" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10715007; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="spore germination protein" /protein_id="NP_388950.1" /db_xref="EnsemblGenomes-Gn:BSU10690" /db_xref="EnsemblGenomes-Tr:CAB12909" /db_xref="GOA:O06718" /db_xref="InterPro:IPR017257" /db_xref="SubtiList:BG13092" /db_xref="UniProtKB/Swiss-Prot:O06718" /translation="MIFTVINRSLEVGDIRMNGVSSSSVFHIGDTESIYLSSIFDTPP ESLIIGPFAPLAPE*" gene complement(1149145..1149321) /gene="gerPD" /locus_tag="BSU_10690" /old_locus_tag="BSU10690" CDS complement(1149318..1149935) /gene="gerPC" /locus_tag="BSU_10700" /old_locus_tag="BSU10700" /function="16.5: Explore" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:10715007" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10715007; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="spore germination protein" /protein_id="NP_388951.1" /db_xref="EnsemblGenomes-Gn:BSU10700" /db_xref="EnsemblGenomes-Tr:CAB12910" /db_xref="GOA:O06719" /db_xref="InterPro:IPR019673" /db_xref="SubtiList:BG13093" /db_xref="UniProtKB/Swiss-Prot:O06719" /translation="MYDQSVSSYLQNLNSFVQQQAIHIQQLERQLKEIQTEMNTMKQR PATTIERVEYKFDQLKIERLDGTLNIGLNPTDPNSVQNFDVSQSTPQIGMMQQEESAQ LMQQIRQNVDMYLTEEIPDILEQLENQYDSRLDDTNRHHVIEDIRKQMDSRIHYYMSH IKKEENTPPAQYAEHIAEHVKRDVIRAVEHFLEHIPSEMKGDEQA*" gene complement(1149318..1149935) /gene="gerPC" /locus_tag="BSU_10700" /old_locus_tag="BSU10700" CDS complement(1149958..1150191) /gene="gerPB" /locus_tag="BSU_10710" /old_locus_tag="BSU10710" /function="16.5: Explore" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:10715007" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10715007; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="spore germination protein" /protein_id="NP_388952.2" /db_xref="EnsemblGenomes-Gn:BSU10710" /db_xref="EnsemblGenomes-Tr:CAB12911" /db_xref="GOA:O06720" /db_xref="InterPro:IPR024255" /db_xref="SubtiList:BG13094" /db_xref="UniProtKB/Swiss-Prot:O06720" /translation="MNFYINQTIQINYLRLESISNSSILQIGSAGSIKSLSNLYNTGS YVEPAPEVSGSGQPLQLQEPDTGSLVPLQPPGR*" gene complement(1149958..1150191) /gene="gerPB" /locus_tag="BSU_10710" /old_locus_tag="BSU10710" CDS complement(1150206..1150427) /gene="gerPA" /locus_tag="BSU_10720" /old_locus_tag="BSU10720" /function="16.5: Explore" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:10715007" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10715007; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="spore germination protein" /protein_id="NP_388953.1" /db_xref="EnsemblGenomes-Gn:BSU10720" /db_xref="EnsemblGenomes-Tr:CAB12912" /db_xref="GOA:O06721" /db_xref="InterPro:IPR019618" /db_xref="SubtiList:BG13095" /db_xref="UniProtKB/Swiss-Prot:O06721" /translation="MPAIVGAFKINAIGTSGVVHIGDCITISPQAQVRTFAGAGSFNT GDSLKVMNYQNATNVYDNDAVDQPIVANA*" gene complement(1150206..1150427) /gene="gerPA" /locus_tag="BSU_10720" /old_locus_tag="BSU10720" S_feature complement(1150428..1150514) /Source="Nicolas_S_feature" /locus_tag="new_1150428_1150514_c" /HighExp="S6, S8, S7, S5, BT, B36, B60, G/S, Pyr, nit" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigK" /TUshortPSig=1 /TUlongSig="SigK" /TUlongPSig="0.992" /label="S380" promotor_-35 1150442..1150448 /Source="Nicolas_upshift_promotors" /id="U862" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.473526473526474" /psig="0.733266733266733" /xcortree=136 /SigmaFactorBS="aaacgctccgacaatggccggcatacgagcacatccttTGTT GAAaaattaaaaaaagACAGGTAAAGTGAAATGACAattccgatttcaattgggctat t" /listShort="S381, S385" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1150462..1150481 /Source="Nicolas_upshift_promotors" /id="U862" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.473526473526474" /psig="0.733266733266733" /xcortree=136 /SigmaFactorBS="aaacgctccgacaatggccggcatacgagcacatccttTGTT GAAaaattaaaaaaagACAGGTAAAGTGAAATGACAattccgatttcaattgggctat t" /listShort="S381, S385" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 1150464..1151119 /Source="Nicolas_S_feature" /locus_tag="new_1150464_1151119" /HighExp="Salt, BC, Sw, S8, Heat, M9-stat, S7, Etha, BMM, Lbtran" /AntisenseName="yisI" /AntisenseCor="3.97396613023396E-2" /AntisenseRegPval="-0.3" /CDS_PredictionProba="0.17396" /TUshortSig="SigA" /TUshortPSig="0.733" /TUlongSig="NA" /TUlongPSig="NA" /label="S381" upshifts 1150464 /Source="Nicolas_upshifts" /id="U862" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.473526473526474" /psig="0.733266733266733" /xcortree=136 /SigmaFactorBS="aaacgctccgacaatggccggcatacgagcacatccttTGTT GAAaaattaaaaaaagACAGGTAAAGTGAAATGACAattccgatttcaattgggctat t" /listShort="S381, S385" /GFF_Attribute="listLong" promotor_-10 complement(1150501..1150520) /Source="Nicolas_upshift_promotors" /id="U863" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1293 /SigmaFactorBS="ttcacaaagagccgatatgtccccttaaaattTCTCTCACAC atatgtgcgtttGTCATAAGCTATCGTGAATAgcccaattgaaatcggaattgtcatt t" /listShort="S380, gerPA, gerPB, gerPC, gerPD, gerPE, gerPF, S379" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1150514) /Source="Nicolas_upshifts" /id="U863" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1293 /SigmaFactorBS="ttcacaaagagccgatatgtccccttaaaattTCTCTCACAC atatgtgcgtttGTCATAAGCTATCGTGAATAgcccaattgaaatcggaattgtcatt t" /listShort="S380, gerPA, gerPB, gerPC, gerPD, gerPE, gerPF, S379" /GFF_Attribute="listLong" S_feature complement(1150516..1150645) /Source="Nicolas_S_feature" /locus_tag="new_1150516_1150645_c" /HighExp="S6, S8, S7, T5.0H, T3.30H, T4.0H, S5, T3.0H, T2.30H, T2.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigK" /TUshortPSig="0.992" /TUlongSig="NA" /TUlongPSig="NA" /label="S382" promotor_-35 complement(1150533..1150542) /Source="Nicolas_upshift_promotors" /id="U863" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1293 /SigmaFactorBS="ttcacaaagagccgatatgtccccttaaaattTCTCTCACAC atatgtgcgtttGTCATAAGCTATCGTGAATAgcccaattgaaatcggaattgtcatt t" /listShort="S380, gerPA, gerPB, gerPC, gerPD, gerPE, gerPF, S379" /GFF_Attribute="listLong" /label="promotor_-35" S_feature complement(1150647..1150849) /Source="Nicolas_S_feature" /locus_tag="new_1150647_1150849_c" /HighExp="T5.0H, T4.0H, T3.30H, S6, M9-stat, T3.0H, S8, S7, T2.30H, S5" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigK" /TUshortPSig="0.976, 0.992" /TUlongSig="NA" /TUlongPSig="NA" /label="S383" downshifts complement(1150690) /Source="Nicolas_upshifts" /id="D581" /incds=0 /nref=13 /ntot=116 /MaxReadThrough="3.97434" /MaxDrop="3.59184" /score="13.5435041" /energy="-15.3" /TU="U865" /idTUdmin="U864" /TUdmin=0 /isTUend="TRUE" CDS complement(1150850..1151020) /gene="pchI" /locus_tag="BSU_10730" /old_locus_tag="BSU10730" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:11679073, 27542896" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11679073, 27542896; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="Spo0A-P phosphatase (iron-metabolism related)" /protein_id="NP_388954.1" /db_xref="EnsemblGenomes-Gn:BSU10730" /db_xref="EnsemblGenomes-Tr:CAB12913" /db_xref="GOA:O06722" /db_xref="InterPro:IPR018540" /db_xref="InterPro:IPR037208" /db_xref="SubtiList:BG13096" /db_xref="UniProtKB/Swiss-Prot:O06722" /translation="MNSKIEEMRITLIETAQKYGMNSKETIQCSQELDILLNTRIKEE MIFGRYLENSRM*" gene complement(1150850..1151020) /gene="pchI" /locus_tag="BSU_10730" /old_locus_tag="BSU10730" misc_feature complement(1151064..1151083) /Source="Nicolas_upshift_promotors" /id="U864" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.386613386613387" /psig="0.976023976023976" /xcortree=2921 /SigmaFactorBS="gcttttttagtcaaattgacgaaaggcaaccttttgagccaa aaTAGGTTATACTAACGATATCctgtatttatatcaaaataaaatctagaattggaga t" /listShort="yisI, S383" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(1151067) /Source="Nicolas_upshifts" /id="U864" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.386613386613387" /psig="0.976023976023976" /xcortree=2921 /SigmaFactorBS="gcttttttagtcaaattgacgaaaggcaaccttttgagccaa aaTAGGTTATACTAACGATATCctgtatttatatcaaaataaaatctagaattggaga t" /listShort="yisI, S383" /GFF_Attribute="listLong" S_feature complement(1151069..1151165) /Source="Nicolas_S_feature" /locus_tag="new_1151069_1151165_c" /HighExp="S6, S8, S7, S5, BT, Pyr, G/S, Glucon, SMMPr, C30" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigK" /TUshortPSig="0.992" /TUlongSig="NA" /TUlongPSig="NA" /label="S384" downshifts 1151076 /Source="Nicolas_upshifts" /id="D582" /incds=0 /nref=3 /ntot=54 /MaxReadThrough="4.52913" /MaxDrop="3.35342" /score="12.6645711" /energy="-10.3" /TU="U862" /idTUdmin="U862" /TUdmin="-176" /isTUend="FALSE" S_feature 1151121..1151285 /Source="Nicolas_S_feature" /locus_tag="new_1151121_1151285" /HighExp="Salt, S8, S7, BC, Heat, H2O2, Sw, Oxctl, MG-0.2, MG-0.1" /AntisenseName="yisJ" /AntisenseCor="0.24461808844813801" /AntisenseRegPval="-4.3" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.733" /TUlongSig="NA" /TUlongPSig="NA" /label="S385" CDS complement(1151166..1152089) /gene="yisJ" /locus_tag="BSU_10740" /old_locus_tag="BSU10740" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="putative spore coat protein, CotH paralog" /protein_id="NP_388955.1" /db_xref="EnsemblGenomes-Gn:BSU10740" /db_xref="EnsemblGenomes-Tr:CAB12914" /db_xref="GOA:O06723" /db_xref="InterPro:IPR014867" /db_xref="SubtiList:BG13097" /db_xref="UniProtKB/Swiss-Prot:O06723" /translation="MERVHLFFHREQLKRKGTAKGLFVTDRSVSPILLTQRDRAEKAS YEISWEKSLLGERTLFLNAEQDDPSLMRRRLAYCFFDQIGVPAPVASYSFLTINGQPE GIYLNIKNHQPAGKRSYGVKTADPRVPLSLFNNDSSAFLHEFFILIRTAGDDELAERI KLYLDVKLFFLWLIGNTCTNQGFYYTFCLNESGRLYVSPMETRSLAVQEWYEEDPLLT KGKTLSSRLLSIPAFRSQYHTLMKNVLKRSFTIERLSPLINEWHLDICQSAADDPFIK KSPFQIEKEQTNILREIEERQDFLQAHLARL*" gene complement(1151166..1152089) /gene="yisJ" /locus_tag="BSU_10740" /old_locus_tag="BSU10740" promotor_-10 complement(1152111..1152130) /Source="Nicolas_upshift_promotors" /id="U865" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.992007992007992" /psig="0.992007992007992" /xcortree=1372 /SigmaFactorBS="aaatccctttttctcaattccgttttcatTTCGTTTCAGgac gggcttgctcTACATATCATACAAATGTCGttttgagaaggaggaaagaatatggagc g" /listShort="yisJ, S384, yisI, S383, S382" /listLong="S380, gerPA, gerPB, gerPC, gerPD, gerPE, gerPF, S379" /label="promotor_-10" upshifts complement(1152122) /Source="Nicolas_upshifts" /id="U865" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.992007992007992" /psig="0.992007992007992" /xcortree=1372 /SigmaFactorBS="aaatccctttttctcaattccgttttcatTTCGTTTCAGgac gggcttgctcTACATATCATACAAATGTCGttttgagaaggaggaaagaatatggagc g" /listShort="yisJ, S384, yisI, S383, S382" /listLong="S380, gerPA, gerPB, gerPC, gerPD, gerPE, gerPF, S379" promotor_-35 complement(1152144..1152153) /Source="Nicolas_upshift_promotors" /id="U865" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.992007992007992" /psig="0.992007992007992" /xcortree=1372 /SigmaFactorBS="aaatccctttttctcaattccgttttcatTTCGTTTCAGgac gggcttgctcTACATATCATACAAATGTCGttttgagaaggaggaaagaatatggagc g" /listShort="yisJ, S384, yisI, S383, S382" /listLong="S380, gerPA, gerPB, gerPC, gerPD, gerPE, gerPF, S379" /label="promotor_-35" promotor_-35 1152173..1152181 /Source="Nicolas_upshift_promotors" /id="U866" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=553 /SigmaFactorBS="cccgtcctgaaacgaaatgaaaacggaattgagaaAAAGGGA TTtcagcattcgaCAGAGAATACATGAAGGAGcattctgatttaaaagatgatggagg a" /listShort="yisK, S386, yisL" /listLong="wprA" /label="promotor_-35" promotor_-10 1152193..1152211 /Source="Nicolas_upshift_promotors" /id="U866" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=553 /SigmaFactorBS="cccgtcctgaaacgaaatgaaaacggaattgagaaAAAGGGA TTtcagcattcgaCAGAGAATACATGAAGGAGcattctgatttaaaagatgatggagg a" /listShort="yisK, S386, yisL" /listLong="wprA" /label="promotor_-10" upshifts 1152198 /Source="Nicolas_upshifts" /id="U866" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=553 /SigmaFactorBS="cccgtcctgaaacgaaatgaaaacggaattgagaaAAAGGGA TTtcagcattcgaCAGAGAATACATGAAGGAGcattctgatttaaaagatgatggagg a" /listShort="yisK, S386, yisL" /listLong="wprA" CDS 1152244..1153149 /gene="mblK" /locus_tag="BSU_10750" /old_locus_tag="BSU10750" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:16847875, 27215790, 22720735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16847875, 27215790, 22720735; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="hydrolase/isomerase involved in remodelling the bacterial envelope" /protein_id="NP_388956.1" /db_xref="EnsemblGenomes-Gn:BSU10750" /db_xref="EnsemblGenomes-Tr:CAB12915" /db_xref="GOA:O06724" /db_xref="InterPro:IPR011234" /db_xref="InterPro:IPR036663" /db_xref="SubtiList:BG13098" /db_xref="UniProtKB/Swiss-Prot:O06724" /translation="MKFATGELYNRMFVGLIIDDEKIMDLQKAEKKLFELETIPGSLI ECIAEGDKFVAHARQLAEWAKKPNDELGSFMYSLSEVKLHAPIPKPSKNIICIGKNYR DHAIEMGSEADIPEHPMVFTKSPVTVTGHGDIVKSHEEVTSQLDYEGELAVVIGKSGT RISKEDAYDHVFGYTIVNDITARDLQKRHKQFFIGKSLDTTCPMGPVLVHKSSIQEPE RLKVETRVNGELRQSGSASDMIFSIPELIETLSKGMTLEAGDIIATGTPSGVGKGFTP PKFLRSGDKIDITIDPIGTLSNQIG*" gene 1152244..1153149 /gene="mblK" /locus_tag="BSU_10750" /old_locus_tag="BSU10750" S_feature 1153150..1153230 /Source="Nicolas_S_feature" /locus_tag="new_1153150_1153230" /HighExp="S2, Lbstat, S1, Etha, SMMPr, M0t90, M40t90, LoTm, T-4.40H, nit" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigH" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S386" promotor_-35 1153200..1153203 /Source="Nicolas_upshift_promotors" /id="U867" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.851148851148851" /psig=1 /xcortree=2462 /SigmaFactorBS="gacccgcccgttttttctgataatcatcTTTGtgacagagga caagttCATGGTACTATAAGTGGGGTaatttatctgatagggggaacatatatgacac a" /listShort="yisL" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1153220..1153239 /Source="Nicolas_upshift_promotors" /id="U867" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.851148851148851" /psig=1 /xcortree=2462 /SigmaFactorBS="gacccgcccgttttttctgataatcatcTTTGtgacagagga caagttCATGGTACTATAAGTGGGGTaatttatctgatagggggaacatatatgacac a" /listShort="yisL" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1153232 /Source="Nicolas_upshifts" /id="U867" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.851148851148851" /psig=1 /xcortree=2462 /SigmaFactorBS="gacccgcccgttttttctgataatcatcTTTGtgacagagga caagttCATGGTACTATAAGTGGGGTaatttatctgatagggggaacatatatgacac a" /listShort="yisL" /GFF_Attribute="listLong" CDS 1153265..1153621 /gene="yisL" /locus_tag="BSU_10760" /old_locus_tag="BSU10760" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406, 27215790; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative integral membrane protein" /protein_id="NP_388957.1" /db_xref="EnsemblGenomes-Gn:BSU10760" /db_xref="EnsemblGenomes-Tr:CAB12916" /db_xref="GOA:O06725" /db_xref="InterPro:IPR010899" /db_xref="SubtiList:BG13099" /db_xref="UniProtKB/Swiss-Prot:O06725" /translation="MTHLHITTWVVALILLFVSYSLYSSGSAKGAKITHMILRLFYIL IILTGAELFVRFANWNGEYAGKMILGIITIGLMEMLLIRKKKEKSTGGLWVGFVIVLL LTVLLGLHLPIGFQLF*" gene 1153265..1153621 /gene="yisL" /locus_tag="BSU_10760" /old_locus_tag="BSU10760" downshifts 1153518 /Source="Nicolas_upshifts" /id="D583" /incds=1 /nref=1 /ntot=44 /MaxReadThrough="4.28837" /MaxDrop="2.46999" /score="41.4247437" /energy="-11.7" /TU="U866,U867" /idTUdmin="U867" /TUdmin="-88" /isTUend="FALSE" downshifts 1153609 /Source="Nicolas_upshifts" /id="D584" /incds=0 /nref=17 /ntot=162 /MaxReadThrough="3.06092" /MaxDrop="3.41506" /score="41.4247437" /energy="-11.7" /TU="U866" /idTUdmin="U867" /TUdmin=3 /isTUend="TRUE" upshifts 1153742 /Source="Nicolas_upshifts" /id="U868" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.486513486513487" /psig="0.732267732267732" /xcortree=2782 /SigmaFactorBS="atattccaaatcatttaaaataaccttaaaattccctgtaag cggtatctcgtcctatgaaatTATGATACCTTCAAGGAGATtcattattttgcaggag g" /listShort="wprA" /GFF_Attribute="listLong" misc_feature 1153745..1153764 /Source="Nicolas_upshift_promotors" /id="U868" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.486513486513487" /psig="0.732267732267732" /xcortree=2782 /SigmaFactorBS="atattccaaatcatttaaaataaccttaaaattccctgtaag cggtatctcgtcctatgaaatTATGATACCTTCAAGGAGATtcattattttgcaggag g" /listShort="wprA" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" CDS 1153789..1156473 /gene="wprA" /locus_tag="BSU_10770" /old_locus_tag="BSU10770" /EC_number="3.4.21.-" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:9004506, 9675284, 10336490, 15205417, 17269748, 21636651, 23180473, 25313396" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9004506, 9675284, 10336490, 15205417, 17269748, 21636651, 23180473, 25313396; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="cell wall-associated protease" /protein_id="NP_388958.1" /db_xref="EnsemblGenomes-Gn:BSU10770" /db_xref="EnsemblGenomes-Tr:CAB12917" /db_xref="GOA:P54423" /db_xref="InterPro:IPR000209" /db_xref="InterPro:IPR015500" /db_xref="InterPro:IPR022398" /db_xref="InterPro:IPR023828" /db_xref="InterPro:IPR034084" /db_xref="InterPro:IPR036852" /db_xref="SubtiList:BG11846" /db_xref="UniProtKB/Swiss-Prot:P54423" /translation="MKRRKFSSVVAAVLIFALIFSLFSPGTKAAAAGAIDQAAALENG KEQTGAMKEPEQVKWYKVTPGATDIQKNSHMALTVKSDSVLNVSVYPSKEKALKDETF EMYRSFTAEDGKSEVIFPYAWSGPYYVKVEYLGEEEPEDGGTAEAAAEAKYTIGYKGT KKQPSDLEEEEACPVEMSVDQKKSGKGILDKLRSIRDEQLSQTAEGKELTSLYYKAAP FIVAKLALNKTARNEIYQDLVTLKPLFDDVSENGASSSYKVTEKDQKAINRLYDKALQ SVPSFLKEEIKKQADRLNMKQLQGKTAGAILTENNIAAKSEVQTTKVIFKVKDNKSLS SVHNEMKGFSASAQSKKDISNVKKAKKLFDNLYSFELPKDEKQNGAYTASAKRVKSAA ATLSKMSNVEFAEPVQEYKSLANDIQYPYQWPLKNNGENGGVKNADVKYEPANTLLSK RKLNDTLIAVVDTGVDSTLADLKGKVRTDLGHNFVGRNNNAMDDQGHGTHVAGIIAAQ SDNGYSMTGLNAKAKIIPVKVLDSAGSGDTEQIALGIKYAADKGAKVINLSLGGGYSR VLEFALKYAADKNVLIAAASGNDGENALSYPASSKYVMSVGATNRMDMTADFSNYGKG LDISAPGSDIPSLVPNGNVTYMSGTSMATPYAAAAAGLLFAQNPKLKRTEVEDMLKKT ADDISFESVDGGEEELYDDYGDPIEIPKTPGVDWHSGYGRLNVMKAVSAADLQLKVNK LESTQTAVRGSAKEGTLIEVMNGKKKLGSAKAGKDNAFKVNIATQKQDQVLYLKATKG DAKTSYKVVVVKGKPSGTPKVNAVKTKDTAVKGKANSKAMIRVKNKSKKVIASAKADA KGTFSVKIKKQKAGTVLYVTAVDTDKKESKEAKVVVEK*" gene 1153789..1156473 /gene="wprA" /locus_tag="BSU_10770" /old_locus_tag="BSU10770" downshifts complement(1153957) /Source="Nicolas_upshifts" /id="D585" /incds=1 /nref=2 /ntot=155 /MaxReadThrough="0.14981" /MaxDrop="3.98572" /score="9.01750245" /energy="-8" /TU="NA" /idTUdmin="U869" /TUdmin=2563 /isTUend="FALSE" downshifts 1156465 /Source="Nicolas_upshifts" /id="D586" /incds=0 /nref=239 /ntot=267 /MaxReadThrough="1.55031" /MaxDrop="8.31576" /score="36.3638154" /energy="-12.3" /TU="NA" /idTUdmin="U868" /TUdmin="-1" /isTUend="TRUE" CDS complement(1156504..1157091) /gene="yisN" /locus_tag="BSU_10780" /old_locus_tag="BSU10780" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_388959.1" /db_xref="EnsemblGenomes-Gn:BSU10780" /db_xref="EnsemblGenomes-Tr:CAB12918" /db_xref="InterPro:IPR024488" /db_xref="SubtiList:BG12239" /db_xref="UniProtKB/Swiss-Prot:O06727" /translation="MKKKETAWMKRKQLLYTEERKWEYGTILIEDGICLIENGEGDIL LADSLQHSPIWIHHKGKWEQAGFQDKLVLACGAENISLSGGERIRYEKSVKRPLMALL DSLDDETFLAFLQHLHSFGLSVFDCVFSYNKGVFSNTSAGQGVSFYHFSNDTAQCAMQ HHYNYSSEGTGDRFEWTASNGKRSIMYTAVQRGRK*" gene complement(1156504..1157091) /gene="yisN" /locus_tag="BSU_10780" /old_locus_tag="BSU10780" promotor_-10 complement(1157106..1157125) /Source="Nicolas_upshift_promotors" /id="U869" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.561438561438561" /psig="0.561438561438561" /xcortree=1023 /SigmaFactorBS="caccttagtaagtttatgcatctataggcagatagttgattt GTCcataaaagagttgtaTGGGACAGGCTTGAATTGGAaagaaaagagaggaatgaag a" /listShort="yisN" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1157125) /Source="Nicolas_upshifts" /id="U869" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.561438561438561" /psig="0.561438561438561" /xcortree=1023 /SigmaFactorBS="caccttagtaagtttatgcatctataggcagatagttgattt GTCcataaaagagttgtaTGGGACAGGCTTGAATTGGAaagaaaagagaggaatgaag a" /listShort="yisN" /GFF_Attribute="listLong" promotor_-35 complement(1157141..1157143) /Source="Nicolas_upshift_promotors" /id="U869" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.561438561438561" /psig="0.561438561438561" /xcortree=1023 /SigmaFactorBS="caccttagtaagtttatgcatctataggcagatagttgattt GTCcataaaagagttgtaTGGGACAGGCTTGAATTGGAaagaaaagagaggaatgaag a" /listShort="yisN" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1157146..1157152 /Source="Nicolas_upshift_promotors" /id="U870" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp="0.543456543456543" /psig="0.543456543456543" /xcortree=1061 /SigmaFactorBS="tttccaattcaagcctgtcccatacaactcttttatggacaa ATCAACTatctgcctatagatGCATAAACTTACTAAGGTGctgaaagaaacgaaattg t" /listShort="S387, asnO, S388" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 1157164 /Source="Nicolas_upshifts" /id="U870" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp="0.543456543456543" /psig="0.543456543456543" /xcortree=1061 /SigmaFactorBS="tttccaattcaagcctgtcccatacaactcttttatggacaa ATCAACTatctgcctatagatGCATAAACTTACTAAGGTGctgaaagaaacgaaattg t" /listShort="S387, asnO, S388" /GFF_Attribute="listLong" promotor_-10 1157167..1157185 /Source="Nicolas_upshift_promotors" /id="U870" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp="0.543456543456543" /psig="0.543456543456543" /xcortree=1061 /SigmaFactorBS="tttccaattcaagcctgtcccatacaactcttttatggacaa ATCAACTatctgcctatagatGCATAAACTTACTAAGGTGctgaaagaaacgaaattg t" /listShort="S387, asnO, S388" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 1157170..1157236 /Source="Nicolas_S_feature" /locus_tag="new_1157170_1157236" /HighExp="S6, S5, S7, S8, B36, S4, BT, G/S, B60, Pyr" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigEF" /TUshortPSig="0.543" /TUlongSig="NA" /TUlongPSig="NA" /label="S387" CDS 1157237..1159081 /gene="asnO" /locus_tag="BSU_10790" /old_locus_tag="BSU10790" /EC_number="6.3.5.4" /function="16.5: Explore" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:10498721, 26735940" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10498721, 26735940; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="asparagine synthetase (sporulation related)" /protein_id="NP_388960.2" /db_xref="EnsemblGenomes-Gn:BSU10790" /db_xref="EnsemblGenomes-Tr:CAB12919" /db_xref="GOA:O05272" /db_xref="InterPro:IPR001962" /db_xref="InterPro:IPR006426" /db_xref="InterPro:IPR014729" /db_xref="InterPro:IPR017932" /db_xref="InterPro:IPR029055" /db_xref="InterPro:IPR033738" /db_xref="SubtiList:BG12240" /db_xref="UniProtKB/Swiss-Prot:O05272" /translation="MCGITGWVDFKKQLVQEKQTMDRMTDTLSKRGPDDSNVWGEHHV LFGHKRLAVVDIEGGRQPMACTYKGDTYTIIYNGELYNTEDLRKELRARGHQFERTSD TEVLLHSYIEWQEDCVDHLNGIFAFAVWDEKRNLLFAARDRLGVKPFFYTKEGSSFLF GSEIKAILAHPDIKARVDRTGLSEIFGLGPSRTPGTGIFKGIKEIRPAHALTFSKDGL NIWRYWNVESEKHTDSFDDTVANVRSLFQDAVTRQLVSDVPVCTFLSGGLDSSAITAI AAGHFEKEGKAPLHTYSIDYEENDKYFQASAFQPNDDGPWIEKMTEAFGTTHHKCVIS QKDLVDHLEEAVLVKDLPGMADVDSSLLWFCREIKKDFVVSLSGECADEIFGGYPWFH TADVESGFPWMRSTEERIKLLSDSWQKKLNLKEYVNAKYEETLAETPLLDGETGVDKA RRQLFYLNMLWFMTNLLDRKDRMSMGASLEVRVPFADHRLVEYVWNIPWEMKMHDNRE KGILRKALEGILPDDILYRKKSPYPKTHHPEYTKGVSEWLKTIRSQKDSVLHTLLDRK QLDQLLETEGSSFKVPWFGQLMKGPQLIAHLAQIHTWFEAYRIDIDER*" gene 1157237..1159081 /gene="asnO" /locus_tag="BSU_10790" /old_locus_tag="BSU10790" S_feature 1159082..1159149 /Source="Nicolas_S_feature" /locus_tag="new_1159082_1159149" /HighExp="S6, S5, S7, B36, BT, S8, S4, B60, S3, Pyr" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigEF" /TUshortPSig="0.543" /TUlongSig="NA" /TUlongPSig="NA" /label="S388" downshifts 1159106 /Source="Nicolas_upshifts" /id="D587" /incds=0 /nref=12 /ntot=43 /MaxReadThrough="3.29969" /MaxDrop="4.67478" /score="3.55879494" /energy="-14.8" /TU="U870" /idTUdmin="U870" /TUdmin="-550" /isTUend="FALSE" CDS complement(1159211..1159690) /gene="yizA" /locus_tag="BSU_10800" /old_locus_tag="BSU10800" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein (sporulation related)" /protein_id="YP_054576.1" /db_xref="EnsemblGenomes-Gn:BSU10800" /db_xref="EnsemblGenomes-Tr:CAE01451" /db_xref="GOA:Q7WY73" /db_xref="InterPro:IPR007837" /db_xref="InterPro:IPR034660" /db_xref="PDB:2QE9" /db_xref="SubtiList:BG14187" /db_xref="UniProtKB/Swiss-Prot:Q7WY73" /translation="MMKFFEYNWQVRDQWFTWCHQLTTEELLKNRLGGVENILYTLFH IIDVEYSWIRAIQGKEDIAVQFADYQTLNKVKSLSNTFRTEIIDVLQTHSDQIKDELV SVPWETGVLYTRDEILHHIIAHEIHHIGQLSVWARELKLSPVSASFIGRTLKPIHSY* " gene complement(1159211..1159690) /gene="yizA" /locus_tag="BSU_10800" /old_locus_tag="BSU10800" upshifts complement(1159710) /Source="Nicolas_upshifts" /id="U871" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.701298701298701" /psig="0.701298701298701" /xcortree=530 /SigmaFactorBS="caatcatcacttcattaatAGAGGAATCacggaaaaaaGGGC TAATTGTTATGATACatgatagtattggagtgagtttagtgatgaaattttttgaata t" /listShort="yizA" /GFF_Attribute="listLong" promotor_-10 complement(1159714..1159732) /Source="Nicolas_upshift_promotors" /id="U871" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.701298701298701" /psig="0.701298701298701" /xcortree=530 /SigmaFactorBS="caatcatcacttcattaatAGAGGAATCacggaaaaaaGGGC TAATTGTTATGATACatgatagtattggagtgagtttagtgatgaaattttttgaata t" /listShort="yizA" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 complement(1159743..1159751) /Source="Nicolas_upshift_promotors" /id="U871" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.701298701298701" /psig="0.701298701298701" /xcortree=530 /SigmaFactorBS="caatcatcacttcattaatAGAGGAATCacggaaaaaaGGGC TAATTGTTATGATACatgatagtattggagtgagtttagtgatgaaattttttgaata t" /listShort="yizA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1159882..1159886 /Source="Nicolas_upshift_promotors" /id="U872" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.338661338661339" /psig="0.988011988011988" /xcortree=2373 /SigmaFactorBS="tgcgtcttgttacttttacaaagtaagaatcggcattttctt cATATAcaattaggaaaaaaCATACTAGACTTGAAGAAGCagtgatacataggagtga g" /listShort="yisP" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 1159899 /Source="Nicolas_upshifts" /id="U872" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.338661338661339" /psig="0.988011988011988" /xcortree=2373 /SigmaFactorBS="tgcgtcttgttacttttacaaagtaagaatcggcattttctt cATATAcaattaggaaaaaaCATACTAGACTTGAAGAAGCagtgatacataggagtga g" /listShort="yisP" /GFF_Attribute="listLong" promotor_-10 1159901..1159920 /Source="Nicolas_upshift_promotors" /id="U872" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.338661338661339" /psig="0.988011988011988" /xcortree=2373 /SigmaFactorBS="tgcgtcttgttacttttacaaagtaagaatcggcattttctt cATATAcaattaggaaaaaaCATACTAGACTTGAAGAAGCagtgatacataggagtga g" /listShort="yisP" /GFF_Attribute="listLong" /label="promotor_-10" CDS 1159922..1160746 /gene="farP" /locus_tag="BSU_10810" /old_locus_tag="BSU10810" /EC_number="3.6.1.27" /experiment="publication(s) with functional evidences, PMID:23295493, 25308276" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 23295493, 25308276; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="farnesyl diphosphate phosphatase" /protein_id="NP_388961.1" /db_xref="EnsemblGenomes-Gn:BSU10810" /db_xref="EnsemblGenomes-Tr:CAB12920" /db_xref="GOA:O06728" /db_xref="InterPro:IPR002060" /db_xref="InterPro:IPR008949" /db_xref="PDB:3WE9" /db_xref="SubtiList:BG12241" /db_xref="UniProtKB/Swiss-Prot:O06728" /translation="MIHRSEKMKEIKEAYQQCGQIVGEYAPACFKALSYLPLKQRQAS WAVLSFCHTAASADEKVLPAFEAKADHVYQRTNNGKQHLWKAFDHAYRTFTLESEPFR EFIAAQKEDAKPYDDLDELLMYAYRTGGAAGLMLLPILTRRKQDQLKQAAVSLGLAIQ LVRFLSDLGTDQQKNRIPRQVMQQFGYTEADLQKGTVNKAFTMTWEYIAFEAEAYLEE CQDALPLFPQYSQKTVKAALHLHRAVLEKIRAKQHDVFQYHFALTETEVKQILSDI*" gene 1159922..1160746 /gene="farP" /locus_tag="BSU_10810" /old_locus_tag="BSU10810" promotor_-35 1160134..1160140 /Source="Nicolas_upshift_promotors" /id="U873" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=261 /SigmaFactorBS="gtattgcccgcatttgaagctaaagctgatcaTGTTTACcaa aggacaaataaCGGTAAACAACATCTATGGaaggcttttgatcatgcgtatcggacct t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1160155..1160173 /Source="Nicolas_upshift_promotors" /id="U873" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=261 /SigmaFactorBS="gtattgcccgcatttgaagctaaagctgatcaTGTTTACcaa aggacaaataaCGGTAAACAACATCTATGGaaggcttttgatcatgcgtatcggacct t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1160162 /Source="Nicolas_upshifts" /id="U873" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=261 /SigmaFactorBS="gtattgcccgcatttgaagctaaagctgatcaTGTTTACcaa aggacaaataaCGGTAAACAACATCTATGGaaggcttttgatcatgcgtatcggacct t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" S_feature 1160756..1162206 /Source="Nicolas_S_feature" /locus_tag="new_1160756_1162206" /HighExp="Salt, Etha, Sw, Cold, G150, G180, G135, LBGtran, Heat, Paraq" /AntisenseName="yisQ" /AntisenseCor="0.19511630802652" /AntisenseRegPval="-2.9" /CDS_PredictionProba="NA" /TUshortSig="NA" /TUshortPSig="NA" /TUlongSig="NA" /TUlongPSig="NA" /label="S389" CDS complement(1160776..1162143) /gene="yisQ" /locus_tag="BSU_10820" /old_locus_tag="BSU10820" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406, 17114254; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative Na(+)-driven efflux transporter" /protein_id="NP_388962.1" /db_xref="EnsemblGenomes-Gn:BSU10820" /db_xref="EnsemblGenomes-Tr:CAB12921" /db_xref="GOA:O07940" /db_xref="InterPro:IPR002528" /db_xref="SubtiList:BG12242" /db_xref="UniProtKB/Swiss-Prot:O07940" /translation="MKQAVFKSTALKKPADKTFSLFSLTWPIFIEVSLYMFMGNADTL MLSQYSDNSVAAVGVSNQILNLIIVMFSFIATGTTVIISQFLGSRQKKEAMEVAYVSI GANFFISLAISAVVFFAAVPLLHMMGLSDALMPDAKVFLQVVGGLSFIQALIMTFSAI LKSYGYTKDTMFVTIGMNILNIAGNFVVIFGLFGFPVLGVAGVAMSTSIARVIGLIAM IVIVNKRIQLKMSLKKVFHMHKEHLRKLLKIGIPSAGEQLSYNLSQMIVTYFIAIMGA QALTTKVYTQNITMFILLFGTAISQGTQILIGRYIGGKQFDAAYERCMKSLYWALGIA AATSVLMTIFSKDLIGLFTQSPDIIATASLLIAMTIILEPGRSFNVIIINSLRAAGDA KFPVYMAMISMWGIGLPLAYLFGIHLGFGLAGIWISFIADEWVRGILMYRRWRSRIWI QKGMA*" gene complement(1160776..1162143) /gene="yisQ" /locus_tag="BSU_10820" /old_locus_tag="BSU10820" promotor_-35 1162175..1162182 /Source="Nicolas_upshift_promotors" /id="U874" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.663336663336663" /psig="0.993006993006993" /xcortree=2737 /SigmaFactorBS="tctaacccctttcgtaaataaaatcaaCGTTTTAAagtgtac ctccatTTCCTTATAATAAAAAGGGAtagaaacgatacttcttgtaaaaatccgactt a" /listShort="yisR, degA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1162196..1162215 /Source="Nicolas_upshift_promotors" /id="U874" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.663336663336663" /psig="0.993006993006993" /xcortree=2737 /SigmaFactorBS="tctaacccctttcgtaaataaaatcaaCGTTTTAAagtgtac ctccatTTCCTTATAATAAAAAGGGAtagaaacgatacttcttgtaaaaatccgactt a" /listShort="yisR, degA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1162208 /Source="Nicolas_upshifts" /id="U874" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.663336663336663" /psig="0.993006993006993" /xcortree=2737 /SigmaFactorBS="tctaacccctttcgtaaataaaatcaaCGTTTTAAagtgtac ctccatTTCCTTATAATAAAAAGGGAtagaaacgatacttcttgtaaaaatccgactt a" /listShort="yisR, degA" /GFF_Attribute="listLong" CDS 1162267..1163130 /gene="yisR" /locus_tag="BSU_10830" /old_locus_tag="BSU10830" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 10704478; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative transcriptional regulator (AraC/XylS family)" /protein_id="NP_388963.1" /db_xref="EnsemblGenomes-Gn:BSU10830" /db_xref="EnsemblGenomes-Tr:CAB12922" /db_xref="GOA:P40331" /db_xref="InterPro:IPR003313" /db_xref="InterPro:IPR009057" /db_xref="InterPro:IPR014710" /db_xref="InterPro:IPR018060" /db_xref="InterPro:IPR018062" /db_xref="SubtiList:BG11064" /db_xref="UniProtKB/Swiss-Prot:P40331" /translation="MPRILFTVPPFPVFIAAGEGVFKKGETHVKRVFSVFDLIYVKQG TLYITENETSFSVEGGEYILLSPGLEHYGTKGSDEATSYYWLHFDEHRYEFTAKGGSN WSELQQEKGSFEELARYGLALPRKGKVQRPQFMAQQFEKLIDYSAENSDLPLRKQILF EELMLHLQKEAFQIPSAKERVAWEAARYLQEHYKEKTTIKDLSLALHYHQDYVSRCMQ QVLGVTPAQYTNRVRMTEAKRLLSSTNDKMGVIAETVGMEDPTYFSKLFKQIEGISPI EYRKIVSRKVQ*" gene 1162267..1163130 /gene="yisR" /locus_tag="BSU_10830" /old_locus_tag="BSU10830" CDS 1163148..1164161 /gene="iolQ" /locus_tag="BSU_10840" /old_locus_tag="BSU10840" /function="16.6: Maintain" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:8407808, 23504016, 28693424" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8407808, 23504016, 28693424; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional repressor of iolX (LacI family)" /protein_id="NP_388964.1" /db_xref="EnsemblGenomes-Gn:BSU10840" /db_xref="EnsemblGenomes-Tr:CAB12923" /db_xref="GOA:P37947" /db_xref="InterPro:IPR000843" /db_xref="InterPro:IPR010982" /db_xref="InterPro:IPR028082" /db_xref="SubtiList:BG10847" /db_xref="UniProtKB/Swiss-Prot:P37947" /translation="MKTTIYDVAKAAGVSITTVSRVINNTGRISDKTRQKVMNVMNEM AYTPNVHAAALTGKRTNMIALVAPDISNPFYGELAKSIEERADELGFQMLICSTDYDP KKETKYFSVLKQKKVDGIIFATGIESHDSMSALEEIASEQIPIAMISQDKPLLPMDIV VIDDVRGGYEAAKHLLSLGHTNIACIIGDGSTTGEKNRIKGFRQAMEEAGVPIDESLI IQTRFSLESGKEEAGKLLDRNAPTAIFAFNDVLACAAIQAARIRGIKVPDDLSIIGFD NTILAEMAAPPLTTVAQPIKEMGRSVIELLAEAIEGKRKAKQKIVLPPELVVRHSTSP LNT*" gene 1163148..1164161 /gene="iolQ" /locus_tag="BSU_10840" /old_locus_tag="BSU10840" downshifts 1164144 /Source="Nicolas_upshifts" /id="D588" /incds=0 /nref=13 /ntot=204 /MaxReadThrough="0.51227" /MaxDrop="3.29173" /score="25.1260914" /energy="-9.6" /TU="NA" /idTUdmin="U874" /TUdmin=22 /isTUend="TRUE" promotor_-35 1164213..1164220 /Source="Nicolas_upshift_promotors" /id="U875" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.91008991008991" /psig="0.988011988011988" /xcortree=334 /SigmaFactorBS="agttgaagccaaaaaaacaTATTGCGTgtaaaccaaaggcgG TGTAAAATATAACCATCTTttgagaaagcgcttgcgcaaaatggcagagcggatagaa c" /listShort="S390, yisS" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1164235..1164254 /Source="Nicolas_upshift_promotors" /id="U875" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.91008991008991" /psig="0.988011988011988" /xcortree=334 /SigmaFactorBS="agttgaagccaaaaaaacaTATTGCGTgtaaaccaaaggcgG TGTAAAATATAACCATCTTttgagaaagcgcttgcgcaaaatggcagagcggatagaa c" /listShort="S390, yisS" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 1164254..1164369 /Source="Nicolas_S_feature" /locus_tag="new_1164254_1164369" /HighExp="Lbstat, M40t90, M0t90, BI, G150, dia0, Mt0, Lbexp, Lbtran, dia5" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.988" /TUlongSig="NA" /TUlongPSig="NA" /label="S390" upshifts 1164254 /Source="Nicolas_upshifts" /id="U875" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.91008991008991" /psig="0.988011988011988" /xcortree=334 /SigmaFactorBS="agttgaagccaaaaaaacaTATTGCGTgtaaaccaaaggcgG TGTAAAATATAACCATCTTttgagaaagcgcttgcgcaaaatggcagagcggatagaa c" /listShort="S390, yisS" /GFF_Attribute="listLong" CDS 1164370..1165398 /gene="iolX" /locus_tag="BSU_10850" /old_locus_tag="BSU10850" /EC_number="1.1.1.370" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:11160890, 20133360, 23109554, 23504016, 28693424" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11160890, 20133360, 23109554, 23504016, 28693424; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="scyllo-inositol 2-dehydrogenase (NAD(+))" /protein_id="NP_388965.1" /db_xref="EnsemblGenomes-Gn:BSU10850" /db_xref="EnsemblGenomes-Tr:CAB12924" /db_xref="GOA:P40332" /db_xref="InterPro:IPR000683" /db_xref="InterPro:IPR004104" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG11065" /db_xref="UniProtKB/Swiss-Prot:P40332" /translation="MEHQVRCAVLGLGRLGYYHAKNLVTSVPGAKLVCVGDPLKGRAE QVARELGIEKWSEDPYEVLEDPGIDAVIIVTPTSTHGDMIIKAAENGKQIFVEKPLTL SLEESKAASEKVKETGVICQVGFMRRFDPAYADAKRRIDAGEIGKPIYYKGFTRDQGA PPAEFIKHSGGIFIDCSIHDYDIARYLLGAEITSVSGHGRILNNPFMEQYGDVDQALT YIEFDSGAAGDVEASRTSPYGHDIRAEVIGTEGSIFIGTLRHQHVTILSAKGSSFDII PDFQTRFHEAYCLELQHFAECVRNGKTPIVTDIDATINLEVGIAATNSFRNGMPVQLD VKRAYTGM*" gene 1164370..1165398 /gene="iolX" /locus_tag="BSU_10850" /old_locus_tag="BSU10850" downshifts 1165420 /Source="Nicolas_upshifts" /id="D589" /incds=0 /nref=4 /ntot=37 /MaxReadThrough="0.33001" /MaxDrop="3.45406" /score="8.69111487" /energy="-13.4" /TU="NA" /idTUdmin="U875" /TUdmin=0 /isTUend="TRUE" CDS complement(1165449..1165958) /gene="yisT" /locus_tag="BSU_10860" /old_locus_tag="BSU10860" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 25651892; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative enzyme regulator of activity" /protein_id="NP_388966.2" /db_xref="EnsemblGenomes-Gn:BSU10860" /db_xref="EnsemblGenomes-Tr:CAB12925" /db_xref="GOA:O07939" /db_xref="InterPro:IPR007837" /db_xref="InterPro:IPR034660" /db_xref="SubtiList:BG12243" /db_xref="UniProtKB/Swiss-Prot:O07939" /translation="MTDAKQFYDYHSWANKKIFTHIENLPEETAYQEVKSVFPSVSDV LLHMCRADYIWLNVLSGVAYQEIIDSAGKLQSAQGNMAAIKQHAAELESQYHDFFSRQ TDLEQTFTMQHPKLGTLESTYADTILHVVNHGTYHRGNVTAMLRQLDHSGVPTDYMYY LYEKRESKG*" gene complement(1165449..1165958) /gene="yisT" /locus_tag="BSU_10860" /old_locus_tag="BSU10860" downshifts complement(1165468) /Source="Nicolas_upshifts" /id="D590" /incds=0 /nref=81 /ntot=251 /MaxReadThrough="-0.0416600000000003" /MaxDrop="7.15629" /score="27.2292301" /energy="-13.4" /TU="NA" /idTUdmin="U876" /TUdmin="-16" /isTUend="TRUE" promotor_-10 complement(1165971..1165989) /Source="Nicolas_upshift_promotors" /id="U876" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp=1 /psig=1 /xcortree=520 /SigmaFactorBS="agcggcaggatattttggggtgtcactcttttgcaattGAAG GAGAAacagatgaaaaAAACGAATTTCTTAGAAAAgggggcatgctgatgactgatgc a" /listShort="yisT" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1165987) /Source="Nicolas_upshifts" /id="U876" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp=1 /psig=1 /xcortree=520 /SigmaFactorBS="agcggcaggatattttggggtgtcactcttttgcaattGAAG GAGAAacagatgaaaaAAACGAATTTCTTAGAAAAgggggcatgctgatgactgatgc a" /listShort="yisT" /GFF_Attribute="listLong" promotor_-35 complement(1166001..1166009) /Source="Nicolas_upshift_promotors" /id="U876" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp=1 /psig=1 /xcortree=520 /SigmaFactorBS="agcggcaggatattttggggtgtcactcttttgcaattGAAG GAGAAacagatgaaaaAAACGAATTTCTTAGAAAAgggggcatgctgatgactgatgc a" /listShort="yisT" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(1166008..1166670) /gene="yisU" /locus_tag="BSU_10870" /old_locus_tag="BSU10870" /function="16.1: Circulate" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative aminoacid related metabolite efflux transporter" /protein_id="NP_388967.1" /db_xref="EnsemblGenomes-Gn:BSU10870" /db_xref="EnsemblGenomes-Tr:CAB12926" /db_xref="GOA:O06730" /db_xref="InterPro:IPR001123" /db_xref="SubtiList:BG13100" /db_xref="UniProtKB/Swiss-Prot:O06730" /translation="MTISLMIEKKCERSFFSMNAIIHGIVLAFGLILPLGVQNVFIFQ QGALQKHIWRALPAVISASVCDTLLIVLAVAGVSVIVQELPVFETVMMAGGFLFLLYM GWVTWNIRPNTSQNEKHTFTPKKQAAFAAAVSLLNPHAILDTIGVIGTSSLQYSGLEK WLFMAACIAVSWIWFISLAIAGRLFQTIDTSGRLMLIVNKCSAAVMWAAAGYFGVSLF CN*" gene complement(1166008..1166670) /gene="yisU" /locus_tag="BSU_10870" /old_locus_tag="BSU10870" promotor_-35 1166689..1166695 /Source="Nicolas_upshift_promotors" /id="U877" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.5004995004995" /psig=1 /xcortree=3135 /SigmaFactorBS="gagagattgtcactaaagtctccagccatttGGTTGGGttag gaaccagccAAATGTATAATGTGTAAAAAaggggggcatgaccttgtcgcaatggcag c" /listShort="yisV" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1166709..1166728 /Source="Nicolas_upshift_promotors" /id="U877" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.5004995004995" /psig=1 /xcortree=3135 /SigmaFactorBS="gagagattgtcactaaagtctccagccatttGGTTGGGttag gaaccagccAAATGTATAATGTGTAAAAAaggggggcatgaccttgtcgcaatggcag c" /listShort="yisV" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1166718 /Source="Nicolas_upshifts" /id="U877" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.5004995004995" /psig=1 /xcortree=3135 /SigmaFactorBS="gagagattgtcactaaagtctccagccatttGGTTGGGttag gaaccagccAAATGTATAATGTGTAAAAAaggggggcatgaccttgtcgcaatggcag c" /listShort="yisV" /GFF_Attribute="listLong" CDS 1166737..1168191 /gene="yisV" /locus_tag="BSU_10880" /old_locus_tag="BSU10880" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15223311, 19383706; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative PLP-dependent transcriptional regulator" /protein_id="NP_388968.2" /db_xref="EnsemblGenomes-Gn:BSU10880" /db_xref="EnsemblGenomes-Tr:CAB12927" /db_xref="GOA:Q796Q6" /db_xref="InterPro:IPR000524" /db_xref="InterPro:IPR004839" /db_xref="InterPro:IPR015421" /db_xref="InterPro:IPR015422" /db_xref="InterPro:IPR015424" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG13101" /db_xref="UniProtKB/Swiss-Prot:Q796Q6" /translation="MTLSQWQPSRKSDVPLHRQIEQYMKDKILHGEWAVGTKIPSQRT LADMFQVNRSTVTAAIDELTSQGLLEGRKGGGTKVVNSTWSVLTAEPPLDWSDYVRSG IHRANSSIIQAINQNEPRADIIRLGTGELSPDLVPADTIGRMFQQINPGVLSLGYEQP KGNRQLREAVADHLKGKKIHVSPSAILIVSGALQALQLISIGLLKRDSVILTEKPSYL QSLHVFQSAGMRLRGLPMDDEGVKAGLVSSNRKQYGGQLLYTIPSFHNPTGTVMSEQR RKEIISLSKKEQMPIIEDDAYGDLWFEEKPPQPLKAMDHEGNILYLGAFSKTVSPGLR IGWLAGPEPVIERLADIKMQTDYGSSGLSQWAAAEWLSQGYYEEHLTWVRRKLKERRD AAVHFLERYAGDIATWRIPAGGFYIWVTFHKNLPVSRFFYELLKRQVLVNPGYIYDGE DRNSIRLSYSYASLGDLETGIKAAAETARRLMMS*" gene 1166737..1168191 /gene="yisV" /locus_tag="BSU_10880" /old_locus_tag="BSU10880" S_feature complement(1168046..1168198) /Source="Nicolas_S_feature" /locus_tag="new_1168046_1168198_c" /HighExp="Diami, Sw, C90, LBGstat, dia15, Paraq, dia5, BC, M40t45, Oxctl" /AntisenseName="yisV" /AntisenseCor="0.69858995161852" /AntisenseRegPval="-40" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.995" /TUlongSig="NA" /TUlongPSig="NA" /label="S391" downshifts complement(1168081) /Source="Nicolas_upshifts" /id="D591" /incds=1 /nref=2 /ntot=84 /MaxReadThrough="2.36735" /MaxDrop="2.81041" /score="-5.131548" /energy="-17.3" /TU="NA" /idTUdmin="U879" /TUdmin="-11" /isTUend="TRUE" CDS complement(1168199..1168837) /gene="yisX" /locus_tag="BSU_10890" /old_locus_tag="BSU10890" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_388970.1" /db_xref="EnsemblGenomes-Gn:BSU10890" /db_xref="EnsemblGenomes-Tr:CAB12929" /db_xref="InterPro:IPR001646" /db_xref="SubtiList:BG13103" /db_xref="UniProtKB/Swiss-Prot:O06733" /translation="MNKIAIQKPNIPENLQTADFHDAVTQDDVISMHLFEDCTICGED IERLCVEKTVFRNVVFIDVSFRHIELTDVIFEKCDLSNADFSGAVIHRTSVKQSKMVG MNVAEATLRNVSFEECHGHFSSFSYSNMKQVRFDHCALMQSECSDTVLQQTHFDGCEL EGASFTGTSLQNMDISTCRFEQLHVSLDKLKGCKIAPEHAIAFARALGAVIV*" gene complement(1168199..1168837) /gene="yisX" /locus_tag="BSU_10890" /old_locus_tag="BSU10890" S_feature complement(1168838..1168972) /Source="Nicolas_S_feature" /locus_tag="new_1168838_1168972_c" /HighExp="Diami, dia15, dia5, C90, BC, Paraq, LBGstat, Lbtran, HiOs, Sw" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.995" /TUlongSig="NA" /TUlongPSig="NA" /label="S392" promotor_-35 1168886..1168891 /Source="Nicolas_upshift_promotors" /id="U878" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.994005994005994" /psig="0.994005994005994" /xcortree=1110 /SigmaFactorBS="cctttgctgcccgaaaaacagaggcttccgggttcaatTTAA TAgatcgttaaggaaatTGATACATATAGTAAATCGtgaagagccttttcttggtaca g" /listShort="S393, yisY" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1168907..1168925 /Source="Nicolas_upshift_promotors" /id="U878" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.994005994005994" /psig="0.994005994005994" /xcortree=1110 /SigmaFactorBS="cctttgctgcccgaaaaacagaggcttccgggttcaatTTAA TAgatcgttaaggaaatTGATACATATAGTAAATCGtgaagagccttttcttggtaca g" /listShort="S393, yisY" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1168908 /Source="Nicolas_upshifts" /id="U878" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.994005994005994" /psig="0.994005994005994" /xcortree=1110 /SigmaFactorBS="cctttgctgcccgaaaaacagaggcttccgggttcaatTTAA TAgatcgttaaggaaatTGATACATATAGTAAATCGtgaagagccttttcttggtaca g" /listShort="S393, yisY" /GFF_Attribute="listLong" S_feature 1168918..1169042 /Source="Nicolas_S_feature" /locus_tag="new_1168918_1169042" /HighExp="S6, S5, S8, S7, S4, BT, B36, S3, G/S, LoTm" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigEF" /TUshortPSig="0.994" /TUlongSig="NA" /TUlongPSig="NA" /label="S393" promotor_-10 complement(1168958..1168977) /Source="Nicolas_upshift_promotors" /id="U879" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.974025974025974" /psig="0.995004995004995" /xcortree=2078 /SigmaFactorBS="tcctgttccctttggctttttcggcctgtaaacGCCTTGACg tataggaagctttCCATTTATGCTTACAAAACAagcgggctgctgtaccaagaaaagg c" /listShort="S392, yisX, S391" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1168972) /Source="Nicolas_upshifts" /id="U879" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.974025974025974" /psig="0.995004995004995" /xcortree=2078 /SigmaFactorBS="tcctgttccctttggctttttcggcctgtaaacGCCTTGACg tataggaagctttCCATTTATGCTTACAAAACAagcgggctgctgtaccaagaaaagg c" /listShort="S392, yisX, S391" /GFF_Attribute="listLong" promotor_-35 complement(1168992..1168999) /Source="Nicolas_upshift_promotors" /id="U879" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.974025974025974" /psig="0.995004995004995" /xcortree=2078 /SigmaFactorBS="tcctgttccctttggctttttcggcctgtaaacGCCTTGACg tataggaagctttCCATTTATGCTTACAAAACAagcgggctgctgtaccaagaaaagg c" /listShort="S392, yisX, S391" /GFF_Attribute="listLong" /label="promotor_-35" CDS 1169043..1169849 /gene="yisY" /locus_tag="BSU_10900" /old_locus_tag="BSU10900" /EC_number="3.1.-.-" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 22882546, 22720735; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative acyl hydrolase or peroxidase" /protein_id="NP_388971.1" /db_xref="EnsemblGenomes-Gn:BSU10900" /db_xref="EnsemblGenomes-Tr:CAB12930" /db_xref="GOA:O06734" /db_xref="InterPro:IPR000073" /db_xref="InterPro:IPR000639" /db_xref="InterPro:IPR029058" /db_xref="SubtiList:BG13104" /db_xref="UniProtKB/Swiss-Prot:O06734" /translation="MGHYIKTEEHVTLFVEDIGHGRPIIFLHGWPLNHKMFEYQMNEL PKRGFRFIGVDLRGYGQSDRPWEGYDYDTMADDVKAVIYTLQLENAILAGFSMGGAIA IRYMARHEGADVDKLILLSAAAPAFTKRPGYPYGMRKQDIDDMIELFKADRPKTLADL GKQFFEKKVSPELRQWFLNLMLEASSYGTIHSGIALRDEDLRKELAAIKVPTLILHGR KDRIAPFDFAKELKRGIKQSELVPFANSGHGAFYEEKEKINSLIAQFSNS*" gene 1169043..1169849 /gene="yisY" /locus_tag="BSU_10900" /old_locus_tag="BSU10900" downshifts 1169842 /Source="Nicolas_upshifts" /id="D592" /incds=0 /nref=4 /ntot=24 /MaxReadThrough="2.64682" /MaxDrop="5.60718" /score="8.70914085" /energy="-6.5" /TU="NA" /idTUdmin="U878" /TUdmin=0 /isTUend="TRUE" CDS complement(1169877..1170476) /gene="yisZ" /locus_tag="BSU_10910" /old_locus_tag="BSU10910" /EC_number="2.7.1.25" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15383836; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative adenylylsulfate kinase" /protein_id="NP_388972.1" /db_xref="EnsemblGenomes-Gn:BSU10910" /db_xref="EnsemblGenomes-Tr:CAB12931" /db_xref="GOA:O06735" /db_xref="InterPro:IPR002891" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG13105" /db_xref="UniProtKB/Swiss-Prot:O06735" /translation="MTHNPNIIWHPAAISKSDRQSLNGHKSCVLWFTGLSGSGKSVLA NAVDEKLYRKGIQSYVLDGDNIRHGLNKDLGFQTGDRIENIRRIGEVAKLFVDSGQMI LTAFISPFREDRDMVRALFPKGEFFEIYVKCPLHVCEQRDPKGLYKKARNGEIKHFTG IDSPYEAPLSPDFIIESDQTSISDGADLIINALQNRGII*" gene complement(1169877..1170476) /gene="yisZ" /locus_tag="BSU_10910" /old_locus_tag="BSU10910" downshifts complement(1169896) /Source="Nicolas_upshifts" /id="D593" /incds=0 /nref=35 /ntot=44 /MaxReadThrough="1.69999" /MaxDrop="6.8011" /score="17.1506785" /energy="-7.3" /TU="NA" /idTUdmin="U880" /TUdmin=0 /isTUend="TRUE" CDS complement(1170473..1171642) /gene="yitA" /locus_tag="BSU_10920" /old_locus_tag="BSU10920" /EC_number="2.7.7.4" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15383836; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative sulfate adenylyltransferase" /protein_id="NP_388973.2" /db_xref="EnsemblGenomes-Gn:BSU10920" /db_xref="EnsemblGenomes-Tr:CAB12932" /db_xref="GOA:O06736" /db_xref="InterPro:IPR002650" /db_xref="InterPro:IPR014729" /db_xref="InterPro:IPR015947" /db_xref="InterPro:IPR020792" /db_xref="InterPro:IPR024951" /db_xref="InterPro:IPR025980" /db_xref="SubtiList:BG13106" /db_xref="UniProtKB/Swiss-Prot:O06736" /translation="MNGNEPHGGVLINRCDPACHFEGCACQAELDQLALSDLELIAIG GYSPLTGFLGEKDYHSVVKEMRLANGLPWSLPITLPVGEKTARQLSAGDHVKLVKDGV TYGMITVTDIYQPDKTQEALSVFKTNDPAHPGVKKLLARPDYYIGGPITVSSLPDKSF EQFYATPAETRAAFQKLGWKTIVGFQTRNPVHRAHEYIQKTALETVDGLLLHPLVGET KSDDIPSDIRMESYQALLNHYYPKDRVMLSVFPAAMRYAGPREAIFHALVRKNYGCTH FIVGRDHAGVGSYYGTYDAQNIFQSFTEEELGIKPLFFEHSFYCRKCGNMGTSKTCPH SPRDHIHLSGTKVRELLRQGKKPPKEFSRPEVAAVLIKGLHQQPVAIKQNSGELQ*" gene complement(1170473..1171642) /gene="yitA" /locus_tag="BSU_10920" /old_locus_tag="BSU10920" S_feature complement(1171643..1171754) /Source="Nicolas_S_feature" /locus_tag="new_1171643_1171754_c" /HighExp="S6, S7, S8, BT, S5, B36, G/S, Pyr, SMMPr, B60" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigK" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S394" CDS complement(1171755..1172465) /gene="yitB" /locus_tag="BSU_10930" /old_locus_tag="BSU10930" /EC_number="1.8.4.8" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15383836; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative phospho-adenylylsulfate reductase" /protein_id="NP_388974.2" /db_xref="EnsemblGenomes-Gn:BSU10930" /db_xref="EnsemblGenomes-Tr:CAB12933" /db_xref="GOA:O06737" /db_xref="InterPro:IPR002500" /db_xref="InterPro:IPR004511" /db_xref="InterPro:IPR011798" /db_xref="InterPro:IPR014729" /db_xref="SubtiList:BG13107" /db_xref="UniProtKB/Swiss-Prot:O06737" /translation="MNETITYDTWNDMLSKQITDQLIDELDVLKWAYRTYGEKIVYAC SFGAEGMVLLDLISKINKNAHIIFLDTGLHFQETYELIETVKERYPGFAIQMLEPELS LTEQGTKYGGELWKHNPNLCCQLRKIEPLKKHLSGMTAWISGLRRDQSPTRKHIQYVN LDQKFELIKICPLIHWTWDDVWTYIRLHNLPYNKLHDQHYPSIGCEMCTLPSPDPNDE RAGRWAGREKTECGLHQE*" gene complement(1171755..1172465) /gene="yitB" /locus_tag="BSU_10930" /old_locus_tag="BSU10930" promotor_-10 complement(1172509..1172528) /Source="Nicolas_upshift_promotors" /id="U880" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1285 /SigmaFactorBS="aatggttccgcacctcattttaggcgggcgcggcacctaaaA CCTGAACCTttatgcaaaaaaTGAATAGTCTGCCTATAACTcgatcaatagataaaaa a" /listShort="yitB, S394, yitA, yisZ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1172531) /Source="Nicolas_upshifts" /id="U880" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1285 /SigmaFactorBS="aatggttccgcacctcattttaggcgggcgcggcacctaaaA CCTGAACCTttatgcaaaaaaTGAATAGTCTGCCTATAACTcgatcaatagataaaaa a" /listShort="yitB, S394, yitA, yisZ" /GFF_Attribute="listLong" promotor_-35 complement(1172541..1172550) /Source="Nicolas_upshift_promotors" /id="U880" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1285 /SigmaFactorBS="aatggttccgcacctcattttaggcgggcgcggcacctaaaA CCTGAACCTttatgcaaaaaaTGAATAGTCTGCCTATAACTcgatcaatagataaaaa a" /listShort="yitB, S394, yitA, yisZ" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1172580..1172589 /Source="Nicolas_upshift_promotors" /id="U881" /multdbtbs="SigE,SigK" /comp="M5" /sig="SigK" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1286 /SigmaFactorBS="aggtgccgcgcccgcctaaaatgaggTGCGGAACCAttaaga gcccggcTGAATATGCTTTTTAGCAAAatggttttatgcccaaggagaggtagtatgc c" /listShort="yitC, yitD" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1172603..1172622 /Source="Nicolas_upshift_promotors" /id="U881" /multdbtbs="SigE,SigK" /comp="M5" /sig="SigK" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1286 /SigmaFactorBS="aggtgccgcgcccgcctaaaatgaggTGCGGAACCAttaaga gcccggcTGAATATGCTTTTTAGCAAAatggttttatgcccaaggagaggtagtatgc c" /listShort="yitC, yitD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1172614 /Source="Nicolas_upshifts" /id="U881" /multdbtbs="SigE,SigK" /comp="M5" /sig="SigK" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1286 /SigmaFactorBS="aggtgccgcgcccgcctaaaatgaggTGCGGAACCAttaaga gcccggcTGAATATGCTTTTTAGCAAAatggttttatgcccaaggagaggtagtatgc c" /listShort="yitC, yitD" /GFF_Attribute="listLong" CDS 1172650..1173336 /gene="slpH" /locus_tag="BSU_10940" /old_locus_tag="BSU10940" /EC_number="3.1.3.71" /function="15.7: Sporulation and germination" /function="16.2: Construct biomass (Anabolism)" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2b: Function from indirect experimental evidences (e.g. phenotypes); PubMedId: 3346220, 11830598, 15383836, 16341843; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="2-phospho,3-sulfolactate phosphatase (sporulation related)" /protein_id="NP_388975.1" /db_xref="EnsemblGenomes-Gn:BSU10940" /db_xref="EnsemblGenomes-Tr:CAB12934" /db_xref="GOA:O06738" /db_xref="InterPro:IPR005238" /db_xref="InterPro:IPR036702" /db_xref="SubtiList:BG13108" /db_xref="UniProtKB/Swiss-Prot:O06738" /translation="MPIAIYQGHHHSLAPADINIVIDVIRAFTVAHYAFIGGAKEILL VRTADEAFALKDTYPDYVLTGEEKGVGISGFDLDNSPKRMAGQNMTDKSLIQKTTNGV TAALGALNAKHLFVTGFSNAKTTAQHVKKLVANDCVINIVASHPSGDDDMACAEYIKG IIEGTNVVTAAEAIERIKGSSVAEKFFDCRQPLFDSEDIVYCTKELTGDFVMKVKQDG EVPTIERVII*" gene 1172650..1173336 /gene="slpH" /locus_tag="BSU_10940" /old_locus_tag="BSU10940" CDS 1173333..1174091 /gene="slpS" /locus_tag="BSU_10950" /old_locus_tag="BSU10950" /EC_number="4.4.1.19" /function="16.14: Store" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2b: Function from indirect experimental evidences (e.g. phenotypes); PubMedId: 11830598, 15014443, 15383836; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="2-phospho-3-sulfolactate synthase" /protein_id="NP_388976.1" /db_xref="EnsemblGenomes-Gn:BSU10950" /db_xref="EnsemblGenomes-Tr:CAB12935" /db_xref="GOA:O06739" /db_xref="InterPro:IPR003830" /db_xref="InterPro:IPR013785" /db_xref="InterPro:IPR036112" /db_xref="PDB:1U83" /db_xref="SubtiList:BG13109" /db_xref="UniProtKB/Swiss-Prot:O06739" /translation="MNDFSLELPVRTNKPRETGQSILIDNGYPLQFFKDAIAGASDYI DFVKFGWGTSLLTKDLEEKISTLKEHDITFFFGGTLFEKYVSQKKVNEFHRYCTYFGC EYIEISNGTLPMTNKEKAAYIADFSDEFLVLSEVGSKDAELASRQSSEEWLEYIVEDM EAGAEKVITEARESGTGGICSSSGDVRFQIVDDIISSDIDINRLIFEAPNKTLQQGFI QKIGPNVNLANIPFHDAIALETLRLGLRSDTFFL*" gene 1173333..1174091 /gene="slpS" /locus_tag="BSU_10950" /old_locus_tag="BSU10950" downshifts 1174088 /Source="Nicolas_upshifts" /id="D594" /incds=0 /nref=2 /ntot=20 /MaxReadThrough="2.37654" /MaxDrop="4.17689" /score="-1.32868938" /energy="-17.6" /TU="NA" /idTUdmin="U881" /TUdmin=0 /isTUend="TRUE" CDS complement(1174136..1174765) /gene="yitE" /locus_tag="BSU_10960" /old_locus_tag="BSU10960" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406, 26335199; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative integral inner membrane protein" /protein_id="NP_388977.1" /db_xref="EnsemblGenomes-Gn:BSU10960" /db_xref="EnsemblGenomes-Tr:CAB12936" /db_xref="GOA:O06740" /db_xref="InterPro:IPR003740" /db_xref="SubtiList:BG13110" /db_xref="UniProtKB/Swiss-Prot:O06740" /translation="MAELLMKAKLTFMIVVGGVLQGLGMSLFLFPHDIPTGGAAGIAV LLHYLFQIPHGFSVWAVNVSMLFTALKWLEMRTFTGTLASITVTSVSVLIFDAVFPDI TSNLWLDLASGAVLLGLGIGLLYKYKISNGGFGALALMISIYRGGNPGTILLIMNCII FMVTASIIDWGIVIQALICQVISTRVIDFIYNIRLTSLPYLTPMYRHKK*" gene complement(1174136..1174765) /gene="yitE" /locus_tag="BSU_10960" /old_locus_tag="BSU10960" promotor_-10 complement(1174799..1174817) /Source="Nicolas_upshift_promotors" /id="U882" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=996 /SigmaFactorBS="tggctcagcctattaagctgggccatttctttattttgaGAC ATAaataatggacagccTCATAAAATGAAAACAGCGgacaagtcttttcataaaggag c" /listShort="yitE" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1174816) /Source="Nicolas_upshifts" /id="U882" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=996 /SigmaFactorBS="tggctcagcctattaagctgggccatttctttattttgaGAC ATAaataatggacagccTCATAAAATGAAAACAGCGgacaagtcttttcataaaggag c" /listShort="yitE" /GFF_Attribute="listLong" promotor_-35 complement(1174832..1174837) /Source="Nicolas_upshift_promotors" /id="U882" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=996 /SigmaFactorBS="tggctcagcctattaagctgggccatttctttattttgaGAC ATAaataatggacagccTCATAAAATGAAAACAGCGgacaagtcttttcataaaggag c" /listShort="yitE" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(1174861..1175976) /gene="yitF" /locus_tag="BSU_10970" /old_locus_tag="BSU10970" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 10960106, 11747447, 27994575; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative enolase superfamily enzyme (isomerase /dehydratase)" /protein_id="NP_388978.1" /db_xref="EnsemblGenomes-Gn:BSU10970" /db_xref="EnsemblGenomes-Tr:CAB12937" /db_xref="GOA:O06741" /db_xref="InterPro:IPR013341" /db_xref="InterPro:IPR013342" /db_xref="InterPro:IPR029017" /db_xref="InterPro:IPR029065" /db_xref="InterPro:IPR036849" /db_xref="PDB:2GDQ" /db_xref="PDB:2GGE" /db_xref="SubtiList:BG13111" /db_xref="UniProtKB/Swiss-Prot:O06741" /translation="MKIVRIETFPLFHRLEKPYGDANGFKRYRTCYLIRIITESGIDG WGECVDWLPALHVGFTKRIIPFLLGKQAGSRLSLVRTIQKWHQRAASAVSMALTEIAA KAADCSVCELWGGRYREEIPVYASFQSYSDSPQWISRSVSNVEAQLKKGFEQIKVKIG GTSFKEDVRHINALQHTAGSSITMILDANQSYDAAAAFKWERYFSEWTNIGWLEEPLP FDQPQDYAMLRSRLSVPVAGGENMKGPAQYVPLLSQRCLDIIQPDVMHVNGIDEFRDC LQLARYFGVRASAHAYDGSLSRLYALFAQACLPPWSKMKNDHIEPIEWDVMENPFTDL VSLQPSKGMVHIPKGKGIGTEINMEIVNRYKWDGSAY*" gene complement(1174861..1175976) /gene="yitF" /locus_tag="BSU_10970" /old_locus_tag="BSU10970" downshifts complement(1174890) /Source="Nicolas_upshifts" /id="D595" /incds=0 /nref=11 /ntot=42 /MaxReadThrough="1.81817" /MaxDrop="4.27426" /score="13.5713023" /energy="-14.5" /TU="NA" /idTUdmin="U883" /TUdmin=0 /isTUend="TRUE" CDS complement(1175985..1177253) /gene="yitG" /locus_tag="BSU_10980" /old_locus_tag="BSU10980" /function="16.8: Protect" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 10960106, 14762009, 15109717, 15849754, 16850406; Product type t : transporter" /codon_start=1 /transl_table=11 /product="putative efflux transporter" /protein_id="NP_388979.1" /db_xref="EnsemblGenomes-Gn:BSU10980" /db_xref="EnsemblGenomes-Tr:CAB12938" /db_xref="GOA:Q796Q1" /db_xref="InterPro:IPR001958" /db_xref="InterPro:IPR011701" /db_xref="InterPro:IPR020846" /db_xref="InterPro:IPR036259" /db_xref="SubtiList:BG13112" /db_xref="UniProtKB/Swiss-Prot:Q796Q1" /translation="MESSKQNNGMTIVAIGSIPLILTLGNSMLIPILPKMKSELHLSQ FQVSLVITVFSLIAAFAIPIVGYLADRFSRKVIIIPCLILYGAGGLLAGFAAGFFDNA YPWVMAGRALQGIGAAGTGPIAMALTGDLFKGAQESKVLGLVEASNGMGKVLSPIIGS LIALLVWYGAFFAFPVFCIISIVLTWIFIKEKKKEKEPPPIGQYAKGLLSVFKHEGRW LFTAYLAGATCLFTLFGILFYLSDVLEKTYDTDGVKKGLILAIPLLVMCVTSYTTGSK IGQKQSLMKKLIVLGLAFMTVSYAALSFIENLVLFISVLVLSSIGSGLVLPCVNSFIT GAVGKERRGFVTSLYGSVRFLGVAIGPPIFGRLMQWSRPGMFLSIAGLTLVVGILVMM LIHVKQNNEETKEKEDPKMAGNRLQPAEER*" gene complement(1175985..1177253) /gene="yitG" /locus_tag="BSU_10980" /old_locus_tag="BSU10980" promotor_-10 complement(1177279..1177290) /Source="Nicolas_upshift_promotors" /id="U883" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=932 /SigmaFactorBS="acaggtatcttctgttcggttttttgctgtctgatcgcTGAA TAAacgaagccatcagGGACATTCTAAGcagaagaaaaggagtgtgctctgagatgga a" /listShort="yitG, yitF" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1177288) /Source="Nicolas_upshifts" /id="U883" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=932 /SigmaFactorBS="acaggtatcttctgttcggttttttgctgtctgatcgcTGAA TAAacgaagccatcagGGACATTCTAAGcagaagaaaaggagtgtgctctgagatgga a" /listShort="yitG, yitF" /GFF_Attribute="listLong" promotor_-35 complement(1177304..1177310) /Source="Nicolas_upshift_promotors" /id="U883" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=932 /SigmaFactorBS="acaggtatcttctgttcggttttttgctgtctgatcgcTGAA TAAacgaagccatcagGGACATTCTAAGcagaagaaaaggagtgtgctctgagatgga a" /listShort="yitG, yitF" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(1177365..1178213) /gene="yitH" /locus_tag="BSU_10990" /old_locus_tag="BSU10990" /EC_number="2.3.1.-" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 23944997; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative N-acetyltransferase" /protein_id="NP_388980.1" /db_xref="EnsemblGenomes-Gn:BSU10990" /db_xref="EnsemblGenomes-Tr:CAB12939" /db_xref="GOA:O06743" /db_xref="InterPro:IPR000182" /db_xref="InterPro:IPR016181" /db_xref="SubtiList:BG13113" /db_xref="UniProtKB/Swiss-Prot:O06743" /translation="MDVVDELIKLHEEHVSGLLRLCGQAGWPDYGEQELKLLVQQGRF FGYQNVSGDIISCIGLFLFGRLTSIGLVIVDKEYQRLGLGRRMVNACITQTDENTAIR LCATKEGLPLYEKAGFHTAGSVRKYSCHSFQPYTKKLDAELTSFREQDFHDLTAADLA AFGGDRSNLLQQLISASCECIIARNQDGQLIGYGLSVQTPANLKFGPIIAPSSDVAAQ IITRLAAGKQGPMRIDIPSEHTSLHDSLIEMGFHKDDEPPILFYQKKAPIQNGHLYAL ISQALG*" gene complement(1177365..1178213) /gene="yitH" /locus_tag="BSU_10990" /old_locus_tag="BSU10990" downshifts complement(1177376) /Source="Nicolas_upshifts" /id="D596" /incds=0 /nref=34 /ntot=209 /MaxReadThrough="2.34135" /MaxDrop="3.51892" /score="14.8688564" /energy="-11.7" /TU="NA" /idTUdmin="U884" /TUdmin=0 /isTUend="TRUE" CDS complement(1178218..1178667) /gene="yitI" /locus_tag="BSU_11000" /old_locus_tag="BSU11000" /EC_number="2.3.1.-" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 23944997; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative N-acetyltransferase" /protein_id="NP_388981.2" /db_xref="EnsemblGenomes-Gn:BSU11000" /db_xref="EnsemblGenomes-Tr:CAB12940" /db_xref="GOA:O06744" /db_xref="InterPro:IPR000182" /db_xref="InterPro:IPR016181" /db_xref="SubtiList:BG13114" /db_xref="UniProtKB/Swiss-Prot:O06744" /translation="MLEVKTISVEDTYEIRHRILRPHQSIEQCKYKEDHAEGSFHLGV FYDGTLISIASFSPQSQPLLTEASAYRLRGMATLEGYRDQKAGSTLIKHAEHKLAESG VQAVWCNARHHVKGYYAKLGWKELGEPFDIPGIGNHIVMYKTLRTSR*" gene complement(1178218..1178667) /gene="yitI" /locus_tag="BSU_11000" /old_locus_tag="BSU11000" promotor_-10 complement(1178688..1178707) /Source="Nicolas_upshift_promotors" /id="U884" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.834165834165834" /psig="0.999000999001" /xcortree=2266 /SigmaFactorBS="cattaatttccaaaagactgcctgatcgaatcgggcagTCtt tttcaacgagattCGTGTTACGATATAGAAAAAcaatcatgaggaggaacattatgct c" /listShort="yitI, yitH" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1178702) /Source="Nicolas_upshifts" /id="U884" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.834165834165834" /psig="0.999000999001" /xcortree=2266 /SigmaFactorBS="cattaatttccaaaagactgcctgatcgaatcgggcagTCtt tttcaacgagattCGTGTTACGATATAGAAAAAcaatcatgaggaggaacattatgct c" /listShort="yitI, yitH" /GFF_Attribute="listLong" promotor_-35 complement(1178723..1178724) /Source="Nicolas_upshift_promotors" /id="U884" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.834165834165834" /psig="0.999000999001" /xcortree=2266 /SigmaFactorBS="cattaatttccaaaagactgcctgatcgaatcgggcagTCtt tttcaacgagattCGTGTTACGATATAGAAAAAcaatcatgaggaggaacattatgct c" /listShort="yitI, yitH" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(1178757..1180595) /gene="samT" /locus_tag="BSU_11010" /old_locus_tag="BSU11010" /EC_number="1.5.1.20" /EC_number="2.1.1.10" /function="16.6: Maintain" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 10094622, 17264075, 20421295, 20951706, 26233166; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="bifunctional homocysteine S-methyltransferase using (R,S)AdoMet and methylenetetrahydrofolate reductase [NAD(P)H]" /protein_id="NP_388982.1" /db_xref="EnsemblGenomes-Gn:BSU11010" /db_xref="EnsemblGenomes-Tr:CAB12941" /db_xref="GOA:O06745" /db_xref="InterPro:IPR003171" /db_xref="InterPro:IPR003726" /db_xref="InterPro:IPR029041" /db_xref="InterPro:IPR036589" /db_xref="SubtiList:BG13115" /db_xref="UniProtKB/Swiss-Prot:O06745" /translation="MGLLEDLQRQVLIGDGAMGTLLYSYGIDRCFEELNISKPEEIQR IHKAYVEAGANIIQTNTYGANYIKLSRHGLEDDIKKMNQEAVKIARASAGDAYVLGTM GGIRTFNKNAYSLDEIKRSFREQLYLLLHEEPDGLLLETYYDLEEAREVLKIARKETD LPIMLNVSMHEQGVLQDGTPLSDALRSIADLGADIVGINCRLGPYHMIEALSEVPIFD DVFLSVYPNSSLPSLEEGRLVYETDDTYFQNSASEFRKQGARIIGGCCGTTPNHIRAM AEAVGGLAPITEKEVKTRAKEFISVHHERTEPGLDEIAAKKRSIIVELDPPKKLSFDK FLSAAAELKEAGIDALTLADNSLATPRISNVACGALVKQQLDMRSLVHITCRDRNIIG LQSHLMGLDTLGLNDVLAITGDPSKIGDFPGATSVYDLTSFDLIRLIKQFNEGLSLSG KPLGKKTNFSVAAAFNPNVRHLDKAVKRLEKKIDCGADYFVSQPVYSEQQLVDIHNET KHLKTPIYIGIMPLTSSRNAEFIHNEIPGIKLSDTIREKMAHAGEDKEKQKAEGLAIA RSLLDTACELFNGIYLITPFLRSDLTAELTSYIQQKDEQRQNIFLH*" gene complement(1178757..1180595) /gene="samT" /locus_tag="BSU_11010" /old_locus_tag="BSU11010" downshifts complement(1178784) /Source="Nicolas_upshifts" /id="D597" /incds=0 /nref=14 /ntot=91 /MaxReadThrough="3.04289" /MaxDrop="4.13744" /score="12.9586126" /energy="-16.2" /TU="U885" /idTUdmin="U885" /TUdmin="-66" /isTUend="FALSE" downshifts complement(1180677) /Source="Nicolas_upshifts" /id="D598" /incds=0 /nref=47 /ntot=128 /MaxReadThrough="8.00128" /MaxDrop="5.61487" /score="22.3754155" /energy="-7.3" /TU="U885,U887" /idTUdmin="U887" /TUdmin="-1079" /isTUend="FALSE" misc_RNA complement(1180685..1180802) /gene="mswK" /locus_tag="BSU_misc_RNA_12" /product="S-adenosylmethionine riboswitch" /experiment="publication(s) with functional evidences, PMID:10094622, 12626738, 12910260, 17381305, 18039762" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10094622, 12626738, 12910260, 17381305, 18039762; Product type n: RNA" /function="16.3: Control" gene complement(1180685..1180802) /gene="mswK" /locus_tag="BSU_misc_RNA_12" promotor_-10 complement(1180854..1180873) /Source="Nicolas_upshift_promotors" /id="U885" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.93906093906094" /psig="0.999000999001" /xcortree=2886 /SigmaFactorBS="aatttataaatttcagataaattttctgattccTATTGATTa ttgtctttattttCGGTAAATTTGGAGAAAGGGaaaaacgccagatatcttttggcac t" /listShort="NA, yitJ" /listLong="yitI, yitH" /label="promotor_-10" upshifts complement(1180868) /Source="Nicolas_upshifts" /id="U885" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.93906093906094" /psig="0.999000999001" /xcortree=2886 /SigmaFactorBS="aatttataaatttcagataaattttctgattccTATTGATTa ttgtctttattttCGGTAAATTTGGAGAAAGGGaaaaacgccagatatcttttggcac t" /listShort="NA, yitJ" /listLong="yitI, yitH" promotor_-35 complement(1180888..1180895) /Source="Nicolas_upshift_promotors" /id="U885" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.93906093906094" /psig="0.999000999001" /xcortree=2886 /SigmaFactorBS="aatttataaatttcagataaattttctgattccTATTGATTa ttgtctttattttCGGTAAATTTGGAGAAAGGGaaaaacgccagatatcttttggcac t" /listShort="NA, yitJ" /listLong="yitI, yitH" /label="promotor_-35" CDS complement(1180909..1181400) /gene="yitK" /locus_tag="BSU_11020" /old_locus_tag="BSU11020" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 12943362, 25329577; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative RNA or cyclic d-GMP binding protein" /protein_id="NP_388983.1" /db_xref="EnsemblGenomes-Gn:BSU11020" /db_xref="EnsemblGenomes-Tr:CAB12942" /db_xref="InterPro:IPR007551" /db_xref="InterPro:IPR035570" /db_xref="InterPro:IPR035571" /db_xref="InterPro:IPR036183" /db_xref="SubtiList:BG13116" /db_xref="UniProtKB/Swiss-Prot:O06746" /translation="MAKESSFDIVSKVELPEVQNAIQIALKEISTRYDFKGSKSDISL DKEELVLVSDDEFKLSQLKDVLVSKLIKRNVPTKNIDYGKVENASGGTVRQRAKLVQG IDKDNAKKINTIIKNSGLKVKSQVQDDQVRVTGKNKDDLQQIISAVRGADLPIDVQFI NFR*" gene complement(1180909..1181400) /gene="yitK" /locus_tag="BSU_11020" /old_locus_tag="BSU11020" promotor_-35 1181418..1181421 /Source="Nicolas_upshift_promotors" /id="U886" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.555444555444555" /psig="0.997002997002997" /xcortree=2548 /SigmaFactorBS="atcaaatgaactttcttttgccatatgaaaacctccataacA TTTaacttatgtgttgaTTATAGTAGAATAAAGAGAAacttccaacagaacaaagaat c" /listShort="yitL" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(1181424..1181443) /Source="Nicolas_upshift_promotors" /id="U887" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.851148851148851" /psig=1 /xcortree=3057 /SigmaFactorBS="acattttttccaatcatcacaaattgattctttgttcTGTTG GAAgtttctctttattcTACTATAATCAACACATAAGttaaatgttatggaggttttc a" /listShort="yitK, NA, yitJ" /listLong="yitI, yitH" /label="promotor_-10" promotor_-10 1181436..1181455 /Source="Nicolas_upshift_promotors" /id="U886" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.555444555444555" /psig="0.997002997002997" /xcortree=2548 /SigmaFactorBS="atcaaatgaactttcttttgccatatgaaaacctccataacA TTTaacttatgtgttgaTTATAGTAGAATAAAGAGAAacttccaacagaacaaagaat c" /listShort="yitL" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1181437 /Source="Nicolas_upshifts" /id="U886" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.555444555444555" /psig="0.997002997002997" /xcortree=2548 /SigmaFactorBS="atcaaatgaactttcttttgccatatgaaaacctccataacA TTTaacttatgtgttgaTTATAGTAGAATAAAGAGAAacttccaacagaacaaagaat c" /listShort="yitL" /GFF_Attribute="listLong" upshifts complement(1181442) /Source="Nicolas_upshifts" /id="U887" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.851148851148851" /psig=1 /xcortree=3057 /SigmaFactorBS="acattttttccaatcatcacaaattgattctttgttcTGTTG GAAgtttctctttattcTACTATAATCAACACATAAGttaaatgttatggaggttttc a" /listShort="yitK, NA, yitJ" /listLong="yitI, yitH" promotor_-35 complement(1181458..1181465) /Source="Nicolas_upshift_promotors" /id="U887" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.851148851148851" /psig=1 /xcortree=3057 /SigmaFactorBS="acattttttccaatcatcacaaattgattctttgttcTGTTG GAAgtttctctttattcTACTATAATCAACACATAAGttaaatgttatggaggttttc a" /listShort="yitK, NA, yitJ" /listLong="yitI, yitH" /label="promotor_-35" CDS 1181499..1182395 /gene="yitL" /locus_tag="BSU_11030" /old_locus_tag="BSU11030" /function="9.4: RNA processing" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 20399190; Product type f : factor" /codon_start=1 /transl_table=11 /product="RNA-binding protein" /protein_id="NP_388984.1" /db_xref="EnsemblGenomes-Gn:BSU11030" /db_xref="EnsemblGenomes-Tr:CAB12943" /db_xref="GOA:O06747" /db_xref="InterPro:IPR003029" /db_xref="InterPro:IPR012340" /db_xref="InterPro:IPR014464" /db_xref="InterPro:IPR022967" /db_xref="InterPro:IPR036388" /db_xref="SubtiList:BG13117" /db_xref="UniProtKB/Swiss-Prot:O06747" /translation="MLTKSAENKRNRKDDSMRPGQQLTLSIDHQTDFGYFLTDGEDTI LLHNSEMTEDIEDRDEVEVFIYVDQQERLAATMKIPIISADEYGWVEVVDKVEDMGVF VDVGLSKDALVATEHLPPYEDVWPQKGDKLYCMLKVTNRGRMFAKPAPEDIISELFTD ASEDLMNKELTGTVYRLIASGSFVITDDGIRCFIHPSERKEEPRLGSRVTGRVIQVKE DGSVNLSLLPRKQDAMSVDAECILTYMRMRNGAMPYSDKSQPDDIRERFNMSKAAFKR ALGHLMKNGKVYQENGWTYEKK*" gene 1181499..1182395 /gene="yitL" /locus_tag="BSU_11030" /old_locus_tag="BSU11030" downshifts 1182382 /Source="Nicolas_upshifts" /id="D599" /incds=0 /nref=232 /ntot=261 /MaxReadThrough="1.78082" /MaxDrop="6.73614" /score="40.361011" /energy="-21.5" /TU="NA" /idTUdmin="U886" /TUdmin=0 /isTUend="TRUE" CDS complement(1182448..1183032) /gene="yitM" /locus_tag="BSU_11040" /old_locus_tag="BSU11040" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 11557812" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_388985.1" /db_xref="EnsemblGenomes-Gn:BSU11040" /db_xref="EnsemblGenomes-Tr:CAB12944" /db_xref="GOA:O06748" /db_xref="InterPro:IPR023888" /db_xref="SubtiList:BG13118" /db_xref="UniProtKB/Swiss-Prot:O06748" /translation="MKKAFLVFLSVVLVTTVFLVKQQESVAQAKQLEYSGEEIFKGFV FAQGEVGKQLPEVFNKAMTDKLNTKQAKAFANQVVADIKKEDADFFDNLKKAVYSKDA LKVDELLKKAGQIVEEKVEAAKEIAASKDDTSRVQAELVNTVDTANYFYYVSYVAAAG ALILIILAIDITPIAISDNVDREMAIRTLVDELN*" gene complement(1182448..1183032) /gene="yitM" /locus_tag="BSU_11040" /old_locus_tag="BSU11040" downshifts complement(1182458) /Source="Nicolas_upshifts" /id="D600" /incds=0 /nref=68 /ntot=158 /MaxReadThrough="1.3386" /MaxDrop="7.40935" /score="10.143892" /energy="-21.5" /TU="NA" /idTUdmin="U888" /TUdmin=0 /isTUend="TRUE" CDS complement(1183029..1183958) /gene="yitO" /locus_tag="BSU_11055" /old_locus_tag="BSU11055" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 11557812, 15849754, 16850406; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative integral inner membrane protein with HTTM domain" /protein_id="NP_388987.2" /db_xref="EnsemblGenomes-Gn:BSU11055" /db_xref="EnsemblGenomes-Tr:CAB12946" /db_xref="GOA:O06750" /db_xref="InterPro:IPR011020" /db_xref="InterPro:IPR023894" /db_xref="SubtiList:BG13120" /db_xref="UniProtKB/Swiss-Prot:O06750" /translation="MLENIKQTITRWDERNPWTNVYGLARSIIALSSLLTLLINHPSL IMKPASGISSYPACKMNLSLFCLGENNYMMLNLFRWVCIAILVLVVIGWRPRITGVLH WYVSYSLQSSLIVIDGGEQAAAVMTFLLLPITLTDPRKWHWSTRPIEGKRTLGKITAF ISYFVIRIQVAVLYFHSTVAKLSQQEWVDGTAVYYFAQEKTIGFNGFFQALTKPIVTS PFVVIPTWGTLLVQIVIFAALFAPKKHWRLILIIAVFMHEIFAVMLGLISFSIIMAGI LILYLTPIDSTIQFTYIRRLLWNKKHKKGEVSV*" gene complement(1183029..1183958) /gene="yitO" /locus_tag="BSU_11055" /old_locus_tag="BSU11055" misc_feature complement(1183114) /Source="Nicolas_upshift_promotors" /id="U888" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.232767232767233" /psig="0.63936063936064" /xcortree=2974 /SigmaFactorBS="agtcatgctgggcctcatcagtttttcgattatcatggccgg cattttgatattgtatctcaCtcctatcgattccacgattcaatttacatatattcgc a" /listShort="yitM" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(1183116) /Source="Nicolas_upshifts" /id="U888" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.232767232767233" /psig="0.63936063936064" /xcortree=2974 /SigmaFactorBS="agtcatgctgggcctcatcagtttttcgattatcatggccgg cattttgatattgtatctcaCtcctatcgattccacgattcaatttacatatattcgc a" /listShort="yitM" /GFF_Attribute="listLong" CDS complement(1183943..1184479) /gene="yitP" /locus_tag="BSU_11070" /old_locus_tag="BSU11070" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 6289325, 11557812" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_388988.1" /db_xref="EnsemblGenomes-Gn:BSU11070" /db_xref="EnsemblGenomes-Tr:CAB12947" /db_xref="GOA:O06751" /db_xref="InterPro:IPR023902" /db_xref="SubtiList:BG13121" /db_xref="UniProtKB/Swiss-Prot:O06751" /translation="MQKSISFFVIFSILWGSLFLFSIIGSLGTTPIPLTKDSKFLMSS ILPQGWGFFSKNPRDTAIGLYEAENASAKVRWPNMRADNLFGLYRYGRSQGVEMGVIY SQVGKEQWTACKEKDLGACKSKAKTVQLKTPAPRPLLCGSYYLTKEDIVPWSYSKYTP SSYQVKSIVKVVISCSKT*" gene complement(1183943..1184479) /gene="yitP" /locus_tag="BSU_11070" /old_locus_tag="BSU11070" promotor_-10 complement(1184515..1184534) /Source="Nicolas_upshift_promotors" /id="U889" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.71028971028971" /psig="0.988011988011988" /xcortree=2975 /SigmaFactorBS="ccttttaacaaaaatggaatttctcatactttttaacCTTTt tattacataaatgTTTTTATATTATGAAAAGTGtaaaaacgattcttcaggttaaaag g" /listShort="yitP" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1184529) /Source="Nicolas_upshifts" /id="U889" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.71028971028971" /psig="0.988011988011988" /xcortree=2975 /SigmaFactorBS="ccttttaacaaaaatggaatttctcatactttttaacCTTTt tattacataaatgTTTTTATATTATGAAAAGTGtaaaaacgattcttcaggttaaaag g" /listShort="yitP" /GFF_Attribute="listLong" promotor_-35 complement(1184549..1184552) /Source="Nicolas_upshift_promotors" /id="U889" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.71028971028971" /psig="0.988011988011988" /xcortree=2975 /SigmaFactorBS="ccttttaacaaaaatggaatttctcatactttttaacCTTTt tattacataaatgTTTTTATATTATGAAAAGTGtaaaaacgattcttcaggttaaaag g" /listShort="yitP" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1184620..1184627 /Source="Nicolas_upshift_promotors" /id="U890" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.767232767232767" /psig=1 /xcortree=3150 /SigmaFactorBS="aaaggaaaaacaggacattttacactgctatatgtGATTGAT AtatagtgtttttttCGATATATTTAAACCATGAAaacgaatcaagttaatgaccgct g" /listShort="yizB, yitQ, yitR" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1184642..1184661 /Source="Nicolas_upshift_promotors" /id="U890" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.767232767232767" /psig=1 /xcortree=3150 /SigmaFactorBS="aaaggaaaaacaggacattttacactgctatatgtGATTGAT AtatagtgtttttttCGATATATTTAAACCATGAAaacgaatcaagttaatgaccgct g" /listShort="yizB, yitQ, yitR" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1184645 /Source="Nicolas_upshifts" /id="U890" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.767232767232767" /psig=1 /xcortree=3150 /SigmaFactorBS="aaaggaaaaacaggacattttacactgctatatgtGATTGAT AtatagtgtttttttCGATATATTTAAACCATGAAaacgaatcaagttaatgaccgct g" /listShort="yizB, yitQ, yitR" /GFF_Attribute="listLong" CDS 1184657..1185004 /gene="yizB" /locus_tag="BSU_11079" /old_locus_tag="BSU11079" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 23504016; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative transcriptional regulator" /protein_id="YP_003097701.1" /db_xref="EnsemblGenomes-Gn:BSU11079" /db_xref="EnsemblGenomes-Tr:CAX52589" /db_xref="GOA:C0H3Y4" /db_xref="InterPro:IPR005149" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="UniProtKB/Swiss-Prot:C0H3Y4" /translation="MKTNQVNDRWIVQFRKGIFELAILSLLRSKPMYGYELTSSLKTT SALAISEGAIYPILKRMTEKGWIEFFWEDSLDGPKRKYYKMTQKGEEMLKERLEKYLE THQALLSLSGDLL*" gene 1184657..1185004 /gene="yizB" /locus_tag="BSU_11079" /old_locus_tag="BSU11079" CDS 1185001..1185588 /gene="yitQ" /locus_tag="BSU_11080" /old_locus_tag="BSU11080" /function="18: Unknown function" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 23504016" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_388989.2" /db_xref="EnsemblGenomes-Gn:BSU11080" /db_xref="EnsemblGenomes-Tr:CAB12948" /db_xref="GOA:O06752" /db_xref="SubtiList:BG13122" /db_xref="UniProtKB/Swiss-Prot:O06752" /translation="MNGQLIIDRYMEELNAELANMPDVERENAIDELKGHITAFVQDR IKAGLSEEELQEAVESEFSHPKELAELMMGDGGETKRRRSLLGKSWISVLLIVTIIAL PLLPSDFRHLPLAVYLMVLAGYVWKRKKLVMFAGVRKNKMRSQKEIVKISRVGAVYLL FLAVVLLLSPFLNALVVLLLIAVSCAAFFLFLNIK*" gene 1185001..1185588 /gene="yitQ" /locus_tag="BSU_11080" /old_locus_tag="BSU11080" CDS 1185608..1185901 /gene="yitR" /locus_tag="BSU_11090" /old_locus_tag="BSU11090" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_388990.1" /db_xref="EnsemblGenomes-Gn:BSU11090" /db_xref="EnsemblGenomes-Tr:CAB12949" /db_xref="GOA:O06753" /db_xref="InterPro:IPR017259" /db_xref="SubtiList:BG13123" /db_xref="UniProtKB/Swiss-Prot:O06753" /translation="MEISINYLLIVIALLFFVVAYFVGIKKQTWMLAGFNEARIRDKD RLARIAGYFFLNSGLFILLNSFISFQGQEQLIPPLILAYGAGVIIYVNKKLVE*" gene 1185608..1185901 /gene="yitR" /locus_tag="BSU_11090" /old_locus_tag="BSU11090" downshifts 1185881 /Source="Nicolas_upshifts" /id="D601" /incds=0 /nref=119 /ntot=240 /MaxReadThrough="1.96008" /MaxDrop="5.72545" /score="2.11183863" /energy="-12.6" /TU="NA" /idTUdmin="U890" /TUdmin=0 /isTUend="TRUE" downshifts 1185925 /Source="Nicolas_upshifts" /id="D602" /incds=0 /nref=1 /ntot=15 /MaxReadThrough="0.34732" /MaxDrop="3.0285" /score="2.11183863" /energy="-12.6" /TU="NA" /idTUdmin="U890" /TUdmin=44 /isTUend="FALSE" CDS 1186037..1187653 /gene="nprB" /locus_tag="BSU_11100" /old_locus_tag="BSU11100" /EC_number="3.4.24.-" /function="16.11: Scavenge (Catabolism)" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:1917867, 16672610" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1917867, 16672610; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="extracellular neutral protease B" /protein_id="NP_388991.1" /db_xref="EnsemblGenomes-Gn:BSU11100" /db_xref="EnsemblGenomes-Tr:CAB12950" /db_xref="GOA:P39899" /db_xref="InterPro:IPR001570" /db_xref="InterPro:IPR011096" /db_xref="InterPro:IPR013856" /db_xref="InterPro:IPR023612" /db_xref="InterPro:IPR025711" /db_xref="SubtiList:BG10691" /db_xref="UniProtKB/Swiss-Prot:P39899" /translation="MRNLTKTSLLLAGLCTAAQMVFVTHASAEESIEYDHTYQTPSYI IEKSPQKPVQNTTQKESLFSYLDKHQTQFKLKGNANSHFRVSKTIKDPKTKQTFFKLT EVYKGIPIYGFEQAVAMKENKQVKSFFGKVHPQIKDVSVTPSISEKKAIHTARRELEA SIGKIEYLDGEPKGELYIYPHDGEYDLAYLVRLSTSEPEPGYWHYFIDAKNGKVIESF NAIHEAAGTGIGVSGDEKSFDVTEQNGRFYLADETRGKGINTFDAKNLNETLFTLLSQ LIGYTGKEIVSGTSVFNEPAAVDAHANAQAVYDYYSKTFGRDSFDQNGARITSTVHVG KQWNNAAWNGVQMVYGDGDGSKFKPLSGSLDIVAHEITHAVTQYSAGLLYQGEPGALN ESISDIMGAMADRDDWEIGEDVYTPGIAGDSLRSLEDPSKQGNPDHYSNRYTGTEDYG GVHINSSIHNKAAYLLAEGGVHHGVQVEGIGREASEQIYYRALTYYVTASTDFSMMKQ AAIEAANDLYGEGSKQSASVEKAYEAVGIL*" gene 1186037..1187653 /gene="nprB" /locus_tag="BSU_11100" /old_locus_tag="BSU11100" downshifts 1187641 /Source="Nicolas_upshifts" /id="D603" /incds=0 /nref=2 /ntot=55 /MaxReadThrough="0.278770000000001" /MaxDrop="3.08544" /score="2.81939887" /energy="-8.6" /TU="NA" /idTUdmin="U890" /TUdmin=1760 /isTUend="FALSE" CDS complement(1187700..1188551) /gene="fakBB" /locus_tag="BSU_11110" /old_locus_tag="BSU11110" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2b: Function from indirect experimental evidences (e.g. phenotypes); PubMedId: 25002480, 26774272, 27435445; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="fatty acid kinase fatty acid binding subunit B" /protein_id="NP_388992.1" /db_xref="EnsemblGenomes-Gn:BSU11110" /db_xref="EnsemblGenomes-Tr:CAB12951" /db_xref="GOA:P70945" /db_xref="InterPro:IPR003797" /db_xref="SubtiList:BG12244" /db_xref="UniProtKB/Swiss-Prot:P70945" /translation="MTVHLIADSATDLPRSYFEEKGIGFIPLRVSLGDKEFEDAVTIH ADQIFEAMQNGETPKTSQASPQTIKNVFLQYAETGDPALYIAFSSGLSGTYQTAVMIA NEVKEEFPDFDLRVIDSKCASLGYGLAVRHAADLCINGNTIQEIETSVKNFCSQLEHI FTVDDLTYLARGGRISKTSAFVGGLLNIKPLLQMEDGKLVPLEKIRGQKKLFKRIIEL MKERGDDWSNQTVGISYAANKEKATDMKHLIEEAFKPKEIIMHPISSAIGSHAGPGTL AIFFLRK*" gene complement(1187700..1188551) /gene="fakBB" /locus_tag="BSU_11110" /old_locus_tag="BSU11110" downshifts complement(1187717) /Source="Nicolas_upshifts" /id="D604" /incds=0 /nref=209 /ntot=263 /MaxReadThrough="0.727580000000001" /MaxDrop="6.86927" /score="-1.24586831" /energy="-7.7" /TU="NA" /idTUdmin="U892" /TUdmin=0 /isTUend="TRUE" promotor_-35 1188098..1188105 /Source="Nicolas_upshift_promotors" /id="U891" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.78021978021978" /psig="0.996003996003996" /xcortree=2481 /SigmaFactorBS="gtaaaaatgtgttcaagctggctgcaaaagtTCTTTACAgac gtttcaatttcTTGTATTGTATTCCCGTTGAtacagagatcggcagcatgccggacag c" /listShort="S395, yitT, S396, ipi" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1188120..1188139 /Source="Nicolas_upshift_promotors" /id="U891" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.78021978021978" /psig="0.996003996003996" /xcortree=2481 /SigmaFactorBS="gtaaaaatgtgttcaagctggctgcaaaagtTCTTTACAgac gtttcaatttcTTGTATTGTATTCCCGTTGAtacagagatcggcagcatgccggacag c" /listShort="S395, yitT, S396, ipi" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 1188125..1188650 /Source="Nicolas_S_feature" /locus_tag="new_1188125_1188650" /HighExp="G180, Paraq, G135, G150, Oxctl, C30, H2O2, LBGstat, LBGexp, Lbexp" /AntisenseName="yitS" /AntisenseCor="-0.45830528686941202" /AntisenseRegPval="-14.6" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.996" /TUlongSig="NA" /TUlongPSig="NA" /label="S395" upshifts 1188127 /Source="Nicolas_upshifts" /id="U891" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.78021978021978" /psig="0.996003996003996" /xcortree=2481 /SigmaFactorBS="gtaaaaatgtgttcaagctggctgcaaaagtTCTTTACAgac gtttcaatttcTTGTATTGTATTCCCGTTGAtacagagatcggcagcatgccggacag c" /listShort="S395, yitT, S396, ipi" /GFF_Attribute="listLong" promotor_-10 complement(1188592..1188611) /Source="Nicolas_upshift_promotors" /id="U892" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.558441558441558" /psig="0.841158841158841" /xcortree=594 /SigmaFactorBS="gctctttcttctttattatgttttcccttaaaacaaatattt gaAcacgattttggcaaattaaTATGATATAGTTGGCTTAACtctcatgataacgagc g" /listShort="yitS" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1188615) /Source="Nicolas_upshifts" /id="U892" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.558441558441558" /psig="0.841158841158841" /xcortree=594 /SigmaFactorBS="gctctttcttctttattatgttttcccttaaaacaaatattt gaAcacgattttggcaaattaaTATGATATAGTTGGCTTAACtctcatgataacgagc g" /listShort="yitS" /GFF_Attribute="listLong" promotor_-35 1188629..1188634 /Source="Nicolas_upshift_promotors" /id="U893" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=738 /SigmaFactorBS="gttaagccaactatatcatattaatttgccaaaatcgTGTTC AaatatttgttttaaGGGAAAACATAATAAAGAAgaaagagcggaggaacatgccatg g" /listShort="yitT, S396, ipi" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 complement(1188631) /Source="Nicolas_upshift_promotors" /id="U892" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.558441558441558" /psig="0.841158841158841" /xcortree=594 /SigmaFactorBS="gctctttcttctttattatgttttcccttaaaacaaatattt gaAcacgattttggcaaattaaTATGATATAGTTGGCTTAACtctcatgataacgagc g" /listShort="yitS" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1188649..1188667 /Source="Nicolas_upshift_promotors" /id="U893" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=738 /SigmaFactorBS="gttaagccaactatatcatattaatttgccaaaatcgTGTTC AaatatttgttttaaGGGAAAACATAATAAAGAAgaaagagcggaggaacatgccatg g" /listShort="yitT, S396, ipi" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1188652 /Source="Nicolas_upshifts" /id="U893" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=738 /SigmaFactorBS="gttaagccaactatatcatattaatttgccaaaatcgTGTTC AaatatttgttttaaGGGAAAACATAATAAAGAAgaaagagcggaggaacatgccatg g" /listShort="yitT, S396, ipi" /GFF_Attribute="listLong" CDS 1188689..1189531 /gene="yitT" /locus_tag="BSU_11120" /old_locus_tag="BSU11120" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406, 23419162, 23824080; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative integral membrane protein" /protein_id="NP_388993.1" /db_xref="EnsemblGenomes-Gn:BSU11120" /db_xref="EnsemblGenomes-Tr:CAB12952" /db_xref="GOA:P39803" /db_xref="InterPro:IPR003740" /db_xref="InterPro:IPR019264" /db_xref="SubtiList:BG10850" /db_xref="UniProtKB/Swiss-Prot:P39803" /translation="MVLDQTKKLLIVIIGALLNAAGLNLFLIPADVYASGFTGVAQLL SSVVDQYAPFYISTGTLLFLLNIPVGILGWLKVGKSFTVYSILSVALTTLFMGILPET SLSHDILLNAVFGGVISAVGIGLTLKYGASTGGLDIVAMVLAKWKDKPVGTYFFILNG IIILTAGLLQGWEKALYTLVTLYVTTRVIDAIHTRHMKLTAMIVTKKADEIKEAIYGK MVRGITTVPAKGAFTNEQKEMMIIVITRYELYDLEKIVKEVDPKAFTNIVQTTGIFGF FRKD*" gene 1188689..1189531 /gene="yitT" /locus_tag="BSU_11120" /old_locus_tag="BSU11120" promotor_-35 1189184..1189192 /Source="Nicolas_upshift_promotors" /id="U894" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.968031968031968" /psig="0.968031968031968" /xcortree=467 /SigmaFactorBS="gcacgtatttcttcattctgaacgggattatcatcttgacgG CAGGATTAttgcaaggttGGGAGAAAGCATTATATACcctggttacactatatgtgac a" /listShort="S396, ipi" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1189203..1189221 /Source="Nicolas_upshift_promotors" /id="U894" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.968031968031968" /psig="0.968031968031968" /xcortree=467 /SigmaFactorBS="gcacgtatttcttcattctgaacgggattatcatcttgacgG CAGGATTAttgcaaggttGGGAGAAAGCATTATATACcctggttacactatatgtgac a" /listShort="S396, ipi" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1189203 /Source="Nicolas_upshifts" /id="U894" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.968031968031968" /psig="0.968031968031968" /xcortree=467 /SigmaFactorBS="gcacgtatttcttcattctgaacgggattatcatcttgacgG CAGGATTAttgcaaggttGGGAGAAAGCATTATATACcctggttacactatatgtgac a" /listShort="S396, ipi" /GFF_Attribute="listLong" S_feature 1189532..1189645 /Source="Nicolas_S_feature" /locus_tag="new_1189532_1189645" /HighExp="Etha, S8, Sw, M9-stat, S7, BC, Gly, S6, Salt, C30" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigH, SigB, SigA" /TUshortPSig="0.968, 0.998, 0.996" /TUlongSig="NA" /TUlongPSig="NA" /label="S396" CDS 1189646..1190005 /gene="ipi" /locus_tag="BSU_11130" /old_locus_tag="BSU11130" /function="16.8: Protect" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:8226659, 24555072" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8226659, 24555072; Product type f: factor" /codon_start=1 /transl_table=11 /product="intracellular proteinase inhibitor BsuPI" /protein_id="NP_388994.1" /db_xref="EnsemblGenomes-Gn:BSU11130" /db_xref="EnsemblGenomes-Tr:CAB12953" /db_xref="GOA:P39804" /db_xref="InterPro:IPR013783" /db_xref="InterPro:IPR020481" /db_xref="PDB:3ISY" /db_xref="SubtiList:BG10852" /db_xref="UniProtKB/Swiss-Prot:P39804" /translation="MENQEVVLSIDAIQEPEQIKFNMSLKNQSERAIEFQFSTGQKFE LVVYDSEHKERYRYSKEKMFTQAFQNLTLESGETYDFSDVWKEVPEPGTYEVKVTFKG RAENLKQVQAVQQFEVK*" gene 1189646..1190005 /gene="ipi" /locus_tag="BSU_11130" /old_locus_tag="BSU11130" downshifts 1189994 /Source="Nicolas_upshifts" /id="D605" /incds=0 /nref=34 /ntot=224 /MaxReadThrough="1.36729" /MaxDrop="5.6855" /score="43.7575824" /energy="-15.6" /TU="NA" /idTUdmin="U893" /TUdmin="-1" /isTUend="TRUE" CDS complement(1190036..1190233) /gene="yizC" /locus_tag="BSU_11139" /old_locus_tag="BSU11139" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein; genus orphan" /protein_id="YP_003097702.1" /db_xref="EnsemblGenomes-Gn:BSU11139" /db_xref="EnsemblGenomes-Tr:CAX52590" /db_xref="InterPro:IPR024217" /db_xref="UniProtKB/Swiss-Prot:C0H3Y5" /translation="MRNELFQQAKSFVQQAVMVTNGFEEGDQEQAILRAKNAVSSAYA NSTDAERQQLHQFQNQLDKLQ*" gene complement(1190036..1190233) /gene="yizC" /locus_tag="BSU_11139" /old_locus_tag="BSU11139" downshifts complement(1190049) /Source="Nicolas_upshifts" /id="D606" /incds=0 /nref=150 /ntot=257 /MaxReadThrough="1.42333" /MaxDrop="8.284" /score="2.35557074" /energy="-17.3" /TU="NA" /idTUdmin="U895" /TUdmin=0 /isTUend="TRUE" S_feature complement(1190234..1190430) /Source="Nicolas_S_feature" /locus_tag="new_1190234_1190430_c" /HighExp="S8, S6, S5, S7, nit, ferm, BT, G/S, Pyr, S4" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.99834599999999996" /TUshortSig="SigGF, SigA" /TUshortPSig="1, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S397" upshifts complement(1190430) /Source="Nicolas_upshifts" /id="U895" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=848 /SigmaFactorBS="aagaaggtccgtattaatttttcccaCTCATAAaccttactt tacccCACCATACTATTgaagacgactcatctcgtcaaagtatggaagggggcagtct c" /listShort="S397, yizC" /GFF_Attribute="listLong" promotor_-10 complement(1190432..1190443) /Source="Nicolas_upshift_promotors" /id="U895" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=848 /SigmaFactorBS="aagaaggtccgtattaatttttcccaCTCATAAaccttactt tacccCACCATACTATTgaagacgactcatctcgtcaaagtatggaagggggcagtct c" /listShort="S397, yizC" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 complement(1190458..1190464) /Source="Nicolas_upshift_promotors" /id="U895" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=848 /SigmaFactorBS="aagaaggtccgtattaatttttcccaCTCATAAaccttactt tacccCACCATACTATTgaagacgactcatctcgtcaaagtatggaagggggcagtct c" /listShort="S397, yizC" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(1190490..1191302) /gene="ribZC" /locus_tag="BSU_11140" /old_locus_tag="BSU11140" /function="4.9: Riboflavin, FMN, and FAD" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1b: Function from experimental evidences in the studied species; PubMedId: 25012491, 26316208; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="5-amino-6-ribitylamino-2,4(1H, 3H)-pyrimidinedione 5'-phosphate phosphatase (promiscuous)" /protein_id="NP_388995.1" /db_xref="EnsemblGenomes-Gn:BSU11140" /db_xref="EnsemblGenomes-Tr:CAB12954" /db_xref="GOA:P70947" /db_xref="InterPro:IPR000150" /db_xref="InterPro:IPR006379" /db_xref="InterPro:IPR023214" /db_xref="InterPro:IPR036412" /db_xref="SubtiList:BG12245" /db_xref="UniProtKB/Swiss-Prot:P70947" /translation="METKPYLIALDLDGTLLKDDKTISENTLHTIQRLKDDGHYVCIS TGRPYRSSSMYYQQMELTTPIVNFNGAFVHHPQDDSWGRYHTSLPLDVVKQLVDISES YNVHNVLAEVIDDVYFHYHDEHLIDAFNMNTTNVTVGDLRENLGEDVTSVLIHAKEED VPAIRSYLSDVHAEVIDHRRWAAPWHVIEIIKSGMNKAVGLQKISDYYGVPRERIIAF GDEDNDLEMLEFAGCGVAMGNGIDAVKQIANRTTATNEEDGVARFLKEYFSL*" gene complement(1190490..1191302) /gene="ribZC" /locus_tag="BSU_11140" /old_locus_tag="BSU11140" promotor_-10 complement(1191340..1191359) /Source="Nicolas_upshift_promotors" /id="U896" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.483516483516484" /psig=1 /xcortree=2075 /SigmaFactorBS="tgtgcccctccttaggataaccataatcataagtgtaacaTG TAGACAataaagatggtaaAAAGCTACACTGTAAGTAAGgcaaaacaagcaaaatcta a" /listShort="yitU, S397, yizC" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 1191360..1191367 /Source="Nicolas_upshift_promotors" /id="U897" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.98001998001998" /psig=1 /xcortree=1854 /SigmaFactorBS="tagattttgcttgttttgccttacttacagtgtagctttTTA CCATCtttattgtctaCATGTTACACTTATGATTATggttatcctaaggaggggcaca t" /listShort="yitV, yitW, S398, yitY, yitZ" /GFF_Attribute="listLong" /label="promotor_-35" upshifts complement(1191360) /Source="Nicolas_upshifts" /id="U896" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.483516483516484" /psig=1 /xcortree=2075 /SigmaFactorBS="tgtgcccctccttaggataaccataatcataagtgtaacaTG TAGACAataaagatggtaaAAAGCTACACTGTAAGTAAGgcaaaacaagcaaaatcta a" /listShort="yitU, S397, yizC" /GFF_Attribute="listLong" promotor_-35 complement(1191373..1191380) /Source="Nicolas_upshift_promotors" /id="U896" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.483516483516484" /psig=1 /xcortree=2075 /SigmaFactorBS="tgtgcccctccttaggataaccataatcataagtgtaacaTG TAGACAataaagatggtaaAAAGCTACACTGTAAGTAAGgcaaaacaagcaaaatcta a" /listShort="yitU, S397, yizC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1191379..1191398 /Source="Nicolas_upshift_promotors" /id="U897" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.98001998001998" /psig=1 /xcortree=1854 /SigmaFactorBS="tagattttgcttgttttgccttacttacagtgtagctttTTA CCATCtttattgtctaCATGTTACACTTATGATTATggttatcctaaggaggggcaca t" /listShort="yitV, yitW, S398, yitY, yitZ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1191381 /Source="Nicolas_upshifts" /id="U897" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.98001998001998" /psig=1 /xcortree=1854 /SigmaFactorBS="tagattttgcttgttttgccttacttacagtgtagctttTTA CCATCtttattgtctaCATGTTACACTTATGATTATggttatcctaaggaggggcaca t" /listShort="yitV, yitW, S398, yitY, yitZ" /GFF_Attribute="listLong" CDS 1191423..1192190 /gene="yitV" /locus_tag="BSU_11150" /old_locus_tag="BSU11150" /EC_number="3.1.-.-" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 28293230; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative carboxylesterase" /protein_id="NP_388996.1" /db_xref="EnsemblGenomes-Gn:BSU11150" /db_xref="EnsemblGenomes-Tr:CAB12955" /db_xref="GOA:P70948" /db_xref="InterPro:IPR001375" /db_xref="InterPro:IPR029058" /db_xref="SubtiList:BG12246" /db_xref="UniProtKB/Swiss-Prot:P70948" /translation="MIQIENQTVSGIPFLHIVKEENRHRAVPLVIFIHGFTSAKEHNL HIAYLLAEKGFRAVLPEALHHGERGEEMAVEELAGHFWDIVLNEIEEIGVLKNHFEKE GLIDGGRIGLAGTSMGGITTLGALTAYDWIKAGVSLMGSPNYVELFQQQIDHIQSQGI EIDVPEEKVQQLMKRLELRDLSLQPEKLQQRPLLFWHGAKDKVVPYAPTRKFYDTIKS HYSEQPERLQFIGDENADHKVPRAAVLKTIEWFETYL*" gene 1191423..1192190 /gene="yitV" /locus_tag="BSU_11150" /old_locus_tag="BSU11150" promotor_-35 1192199..1192205 /Source="Nicolas_upshift_promotors" /id="U898" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.723276723276723" /psig=1 /xcortree=2071 /SigmaFactorBS="aaacgattgaatggtttgaaacgtacttataaagcactaaGT TATTAacaagagctgaattTACGTTATACTGTAGAAAAAaggagtgagggaacgtgga a" /listShort="yitW, S398, yitY, yitZ" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 1192219 /Source="Nicolas_upshifts" /id="U898" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.723276723276723" /psig=1 /xcortree=2071 /SigmaFactorBS="aaacgattgaatggtttgaaacgtacttataaagcactaaGT TATTAacaagagctgaattTACGTTATACTGTAGAAAAAaggagtgagggaacgtgga a" /listShort="yitW, S398, yitY, yitZ" /GFF_Attribute="listLong" promotor_-10 1192220..1192239 /Source="Nicolas_upshift_promotors" /id="U898" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.723276723276723" /psig=1 /xcortree=2071 /SigmaFactorBS="aaacgattgaatggtttgaaacgtacttataaagcactaaGT TATTAacaagagctgaattTACGTTATACTGTAGAAAAAaggagtgagggaacgtgga a" /listShort="yitW, S398, yitY, yitZ" /GFF_Attribute="listLong" /label="promotor_-10" CDS 1192254..1192562 /gene="yitW" /locus_tag="BSU_11160" /old_locus_tag="BSU11160" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 9209063; Product type f: factor" /codon_start=1 /transl_table=11 /product="putative protein involved in Fe-S cluster assembly, PaaD-like" /protein_id="NP_388997.1" /db_xref="EnsemblGenomes-Gn:BSU11160" /db_xref="EnsemblGenomes-Tr:CAB12956" /db_xref="InterPro:IPR002744" /db_xref="InterPro:IPR034904" /db_xref="SubtiList:BG12247" /db_xref="UniProtKB/Swiss-Prot:P70949" /translation="MEEALKENIMGALEQVVDPELGVDIVNLGLVYDVDMDEDGLTHI TMTLTSMGCPLAPIIVDEVKKALADLPEVKDTEVHIVWNPPWTRDKMSRYAKIALGIQ *" gene 1192254..1192562 /gene="yitW" /locus_tag="BSU_11160" /old_locus_tag="BSU11160" downshifts 1192547 /Source="Nicolas_upshifts" /id="D607" /incds=0 /nref=3 /ntot=55 /MaxReadThrough="5.65659" /MaxDrop="4.5598" /score="14.9971829" /energy="-14.7" /TU="U897,U898" /idTUdmin="U897" /TUdmin="-2244" /isTUend="FALSE" S_feature 1192592..1192857 /Source="Nicolas_S_feature" /locus_tag="new_1192592_1192857" /HighExp="Etha, dia15, dia5, H2O2, LoTm, Salt, S6, Diami, S8, HiOs" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba=1 /TUshortSig="SigA, SigA" /TUshortPSig="1, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S398" CDS 1192858..1194288 /gene="yitY" /locus_tag="BSU_11170" /old_locus_tag="BSU11170" /EC_number="1.-.-.-" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 12682299, 16956367; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative FMN/FAD-binding oxidoreductase" /protein_id="NP_388999.3" /db_xref="EnsemblGenomes-Gn:BSU11170" /db_xref="EnsemblGenomes-Tr:CAB12958" /db_xref="GOA:Q796P5" /db_xref="InterPro:IPR006094" /db_xref="InterPro:IPR016164" /db_xref="InterPro:IPR016166" /db_xref="InterPro:IPR016167" /db_xref="InterPro:IPR016169" /db_xref="InterPro:IPR036318" /db_xref="SubtiList:BG12249" /db_xref="UniProtKB/Swiss-Prot:Q796P5" /translation="MKKKLLAFALCTGAYAALFAYSVNSEQKTATSEMTDVSRLMPVK IKQTVKGQEEEMLIDTVKEANRKNIKISIAGAQHSMGGHTYYEDGIVLDMTGYNKILS LDQEKKTIRVQSGATWNDIQKYVNPYGLAVKVMQSQNIFTIGGSLSANAHGRDIRYGS LIDTVKSFRLLKADGMIITVTPKDDLFTAVIGGYGLFGVILDVTLELTDDELYVMKTE KMNYSTYSDYFSKHVKGNPDVRMHLARISTAKKGFLKDMYVTNYVLANHQDQLSSYSE LKEDEYTGATKFALGLSRRYEWGRNWLWDTQQSYFLSQNGTEISRNNVMRSESKFLEY ENNDNTDVLQEYFVPVKEYGSYIDDLRQTLSDEDLNLLNITIRYVQKNEKADLSYAKD DMFSLVLLINEGFSKEDQADTARIIRRMTDVAIKHGGSYYLPYMTYQTKAQMRQAYPK SEAFFQKKRTYDPDERFMNYFYQRYK*" gene 1192858..1194288 /gene="yitY" /locus_tag="BSU_11170" /old_locus_tag="BSU11170" CDS 1194333..1194827 /gene="yitZ" /locus_tag="BSU_11180" /old_locus_tag="BSU11180" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative transport protein" /protein_id="NP_389000.1" /db_xref="EnsemblGenomes-Gn:BSU11180" /db_xref="EnsemblGenomes-Tr:CAB12959" /db_xref="GOA:P70952" /db_xref="InterPro:IPR011701" /db_xref="InterPro:IPR020846" /db_xref="InterPro:IPR036259" /db_xref="SubtiList:BG12250" /db_xref="UniProtKB/Swiss-Prot:P70952" /translation="MFFASSLIFPFYILFVKNIGSSYTQFGFSYGLFGLSGALIYPLL GRLSERFDSRYFLLLNSWGMAVLLLYVPHIGSVVQVYIVQVLLGLFGAMQKHGEKVLI ANFTDSGERGKKIGNYHFWTAVFSAAAIMLGGFLADFFTVQMIFYASSILYFLSGLMM MKTG*" gene 1194333..1194827 /gene="yitZ" /locus_tag="BSU_11180" /old_locus_tag="BSU11180" downshifts 1194791 /Source="Nicolas_upshifts" /id="D608" /incds=0 /nref=49 /ntot=208 /MaxReadThrough="1.74762" /MaxDrop="4.22077" /score="34.1294744" /energy="-13.2" /TU="NA" /idTUdmin="U897" /TUdmin=0 /isTUend="TRUE" promotor_-35 1194965..1194972 /Source="Nicolas_upshift_promotors" /id="U899" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.861138861138861" /psig="0.999000999001" /xcortree=2913 /SigmaFactorBS="gcggaattcccattgaacagaaaatttataaatgaataaaaa tattaaatatacGATTGAATtaatttttattcaTGTTATAATGTTAAATAATTtcaca a" /listShort="argC, argJ, argB, argD, carA, carB, argF, yjzC" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 1194971 /Source="Nicolas_upshifts" /id="U899" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.861138861138861" /psig="0.999000999001" /xcortree=2913 /SigmaFactorBS="gcggaattcccattgaacagaaaatttataaatgaataaaaa tattaaatatacGATTGAATtaatttttattcaTGTTATAATGTTAAATAATTtcaca a" /listShort="argC, argJ, argB, argD, carA, carB, argF, yjzC" /GFF_Attribute="listLong" promotor_-10 1194986..1195005 /Source="Nicolas_upshift_promotors" /id="U899" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.861138861138861" /psig="0.999000999001" /xcortree=2913 /SigmaFactorBS="gcggaattcccattgaacagaaaatttataaatgaataaaaa tattaaatatacGATTGAATtaatttttattcaTGTTATAATGTTAAATAATTtcaca a" /listShort="argC, argJ, argB, argD, carA, carB, argF, yjzC" /GFF_Attribute="listLong" /label="promotor_-10" CDS 1195034..1196071 /gene="argC" /locus_tag="BSU_11190" /old_locus_tag="BSU11190" /EC_number="1.2.1.38" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:2117746, 3005232, 3106155, 6096674, 6096675, 8025667, 18455186" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 2117746, 3005232, 3106155, 6096674, 6096675, 8025667, 18455186; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="N-acetylglutamate gamma-semialdehyde dehydrogenase" /protein_id="NP_389001.2" /db_xref="EnsemblGenomes-Gn:BSU11190" /db_xref="EnsemblGenomes-Tr:CAB12960" /db_xref="GOA:P23715" /db_xref="InterPro:IPR000534" /db_xref="InterPro:IPR000706" /db_xref="InterPro:IPR012280" /db_xref="InterPro:IPR023013" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG10191" /db_xref="UniProtKB/Swiss-Prot:P23715" /translation="MKIGIVGATGYGGTELVRILSHHPHAEECILYSSSGEGNVYSEG YPHLTGLADQQLKPIDMNTIKHEIDIMFLAAPPGVSSELTPKLADAGITVIDLSGDLR IKEPAEYEKWYKRTAAPKAVIQEAVYGLAELNQLQIQQAKLIANPGCFPTAVLLGLAP LAQKKLLDESFVIVDAKTGVSGAGRKASMGTHFSELNDNFKIYKVNEHQHTPEIEQAL NEWQPGLGPITFSAHLVPMTRGIMATMYTRLTCDLTADDLHDLYSEFYQDSYFVRVRP KGQYPQTKEVYGSNFCDIAVTLDERTNRVTIVSVIDNLMKGAAGQAVQNFNLMNGWNE ETGLTITPIYP*" gene 1195034..1196071 /gene="argC" /locus_tag="BSU_11190" /old_locus_tag="BSU11190" CDS 1196091..1197311 /gene="argJ" /locus_tag="BSU_11200" /old_locus_tag="BSU11200" /EC_number="2.3.1.1" /EC_number="2.3.1.35" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:8025667, 10931207, 16409639, 24163341" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8025667, 10931207, 16409639, 24163341; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="ornithine acetyltransferase; amino-acid acetyltransferase" /protein_id="NP_389002.2" /db_xref="EnsemblGenomes-Gn:BSU11200" /db_xref="EnsemblGenomes-Tr:CAB12961" /db_xref="GOA:P36843" /db_xref="InterPro:IPR002813" /db_xref="InterPro:IPR016117" /db_xref="SubtiList:BG10192" /db_xref="UniProtKB/Swiss-Prot:P36843" /translation="MIQLSEDQIVKVTGDVSSPKGFQAKGVHCGLRYSKKDLGVIISE TPAVSAAVYTQSHFQAAPIKVTQDSLKHGPTLKAVIVNSAIANACTGEQGLKDAYTMR ESFASQLGIEPELVAVSSTGVIGEHLDMEKIHAGIELLKETPAGSGDFEEAILTTDTV IKQTCYELAIGGKTVTIGGAAKGSGMIHPNMATMLGFVTTDAAIEEKALQKALREITD VSFNQITVDGETSTNDMVLVMANGCAENECLTEDHPDWPVFKKALLLTCEDLAKEIAR DGEGATKLIEAQVQGAKNNLDANVIAKKIVGSNLVKTAVYGTDANWGRIIGAIGHSAA QVTAEEVEVYLGGQCLFKNNEPQPFSESIAKEYLEGDEITIVIKMAEGDGNGRAWGCD LTYDYIKINASYRT*" gene 1196091..1197311 /gene="argJ" /locus_tag="BSU_11200" /old_locus_tag="BSU11200" CDS 1197326..1198102 /gene="argB" /locus_tag="BSU_11210" /old_locus_tag="BSU11210" /EC_number="2.7.2.8" /experiment="publication(s) with functional evidences, PMID:3005232, 8473852" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 3005232, 8473852; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="N-acetylglutamate 5-phosphotransferase (acetylglutamate kinase)" /protein_id="NP_389003.1" /db_xref="EnsemblGenomes-Gn:BSU11210" /db_xref="EnsemblGenomes-Tr:CAB12962" /db_xref="GOA:P68729" /db_xref="InterPro:IPR001048" /db_xref="InterPro:IPR001057" /db_xref="InterPro:IPR004662" /db_xref="InterPro:IPR036393" /db_xref="SubtiList:BG10193" /db_xref="UniProtKB/Swiss-Prot:P68729" /translation="MKKTIVFKCGGSVIRELSEEFYQNLKELRASGWKLAIVHGGGPE ITNMLKRLNIKTEFSGGQRKTTKPVLEVAEMVLSGSVNKFFVAELAKHGLRAAGISGK DGGLLEADYLDPETYGEVGEIKKVDASMVNALMENGIIPVIAPLSMTSDCKTLNVNAD LAASAVAGALEADKLMFVTDVDGIMKEKQRLDVLTPKEIQMLIKQEVITGGMIPKVNS ALSALSDQVSEVMIVNGKGSFFAEQTFQGTKIVKAKEAVS*" gene 1197326..1198102 /gene="argB" /locus_tag="BSU_11210" /old_locus_tag="BSU11210" CDS 1198099..1199256 /gene="argD" /locus_tag="BSU_11220" /old_locus_tag="BSU11220" /EC_number="2.6.1.11" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 17012789; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="N-acetylornithine aminotransferase" /protein_id="NP_389004.2" /db_xref="EnsemblGenomes-Gn:BSU11220" /db_xref="EnsemblGenomes-Tr:CAB12963" /db_xref="GOA:P36839" /db_xref="InterPro:IPR004636" /db_xref="InterPro:IPR005814" /db_xref="InterPro:IPR015421" /db_xref="InterPro:IPR015422" /db_xref="InterPro:IPR015424" /db_xref="SubtiList:BG10194" /db_xref="UniProtKB/Swiss-Prot:P36839" /translation="MSSLFQTYGRWDIDIKKAKGTYVEDQNGKTYLDFIQGIAVSNLG HCHEAVTEAVKKQLDSVWHVSNLFQNSLQEQAAQKLAAHSAGDLVFFCNSGAEANEGA IKLARKATGKTKIITFLQSFHGRTYAGMAATGQDKIKTGFGPMLGGFHYLPYNDPSAF KALGEEGDIAAVMLETVQGEGGVNPASAEFLSAVQSFCKEKQALLIIDEIQTGIGRTG KGFAYEHFGLSPDIITVAKGLGNGFPVGAVIGKKQLGEAFTPGSHGTTFGGNMLAMAA VNATLQIVFQPDFLQEAADKGAFLKEQLEAELKSPFVKQIRGKGLMLGIECDGPVADI IAELQTLGLLVLPAGPNVIRLLPPLTVTKDEIAEAVSKLKQAIAHHSAVNQ*" gene 1198099..1199256 /gene="argD" /locus_tag="BSU_11220" /old_locus_tag="BSU11220" CDS 1199327..1200388 /gene="carA" /locus_tag="BSU_11230" /old_locus_tag="BSU11230" /EC_number="6.3.5.5" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:216664, 230177, 1116335" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 216664, 230177, 1116335; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="arginine-specific carbamoyl-phosphate synthetase(small subunit)" /protein_id="NP_389005.2" /db_xref="EnsemblGenomes-Gn:BSU11230" /db_xref="EnsemblGenomes-Tr:CAB12964" /db_xref="GOA:P36838" /db_xref="InterPro:IPR002474" /db_xref="InterPro:IPR006274" /db_xref="InterPro:IPR017926" /db_xref="InterPro:IPR029062" /db_xref="InterPro:IPR035686" /db_xref="InterPro:IPR036480" /db_xref="SubtiList:BG10195" /db_xref="UniProtKB/Swiss-Prot:P36838" /translation="MEGYLVLEDGTSFSGELDGHENCTGEAVFFTGMTGYQEVLTDPS YKGQIIVFTYPLIGNYGINEKDFESKKPQVKAAVVYEACDHFSHYEAVYSLKEYLQKW NIPLLTHVDTRAVVKKIRANGTMGATVTASKEGAEIALQPENVAEQASAQEISTFGDG NKHIALIDFGYKKSIASSLVKRGCKVTVVPYQQMEAVYNIKPDGIVLSNGPGDPKAIQ PYLGKIKSIISRFPTLGICLGHQLIALAFGGNTFKLPFGHRGANHPVIDRKTKRVFMT SQNHSYVVDEQSINEEELTIRFHHVNDTSVEGLAHKKLPVMSVQFHPEAHPGPAESEW IFDDYLKNVIPARREIAHA*" gene 1199327..1200388 /gene="carA" /locus_tag="BSU_11230" /old_locus_tag="BSU11230" misc_feature complement(1200222..1200241) /Source="Nicolas_upshift_promotors" /id="U900" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.869130869130869" /psig="0.949050949050949" /xcortree=2066 /SigmaFactorBS="gtggaattgaacactcatgacaggcagttttttatgggcaag cccttcaacTGACGTATCATTGACATGATgaaacctgatggtgagctcttcttcatta a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(1200232) /Source="Nicolas_upshifts" /id="U900" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.869130869130869" /psig="0.949050949050949" /xcortree=2066 /SigmaFactorBS="gtggaattgaacactcatgacaggcagttttttatgggcaag cccttcaacTGACGTATCATTGACATGATgaaacctgatggtgagctcttcttcatta a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" CDS 1200381..1203473 /gene="carB" /locus_tag="BSU_11240" /old_locus_tag="BSU11240" /EC_number="6.3.5.5" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:216664, 1116335" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 216664, 1116335; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="arginine-specific carbamoyl-phosphate synthetase(large subunit)" /protein_id="NP_389006.3" /db_xref="EnsemblGenomes-Gn:BSU11240" /db_xref="EnsemblGenomes-Tr:CAB12965" /db_xref="GOA:P18185" /db_xref="InterPro:IPR005479" /db_xref="InterPro:IPR005480" /db_xref="InterPro:IPR005483" /db_xref="InterPro:IPR006275" /db_xref="InterPro:IPR011761" /db_xref="InterPro:IPR013815" /db_xref="InterPro:IPR016185" /db_xref="InterPro:IPR036897" /db_xref="SubtiList:BG10196" /db_xref="UniProtKB/Swiss-Prot:P18185" /translation="MPKDTSISSILVIGSGPIIIGQAAEFDYSGTQGCIALKEEGYRV ILVNSNPATIMTDEAFADEIYFEPLTAESLTAIIKKERPDGLLANLGGQTALNLAVEL EETGVLKEHGVKLLGTSVETIQKGEDREKFRSLMNELKQPVPESEIVDNEADALHFAE SIGFPVIIRPAYTLGGKGGGIAPDKEAFTAMIKQALLASPINQCLVEKSIAGFKEIEY EVMRDSNNTCITVCNMENIDPVGVHTGDSIVVAPSQTLTDEDYQMLRTASLTIISALD VVGGCNIQFALDPFSKQYYVIEVNPRVSRSSALASKATGYPIAKMAAKLAVGYTLDEL KNPLTGSTYASFEPALDYVIVKFPRWPFDKFKNADRKLGTKMKATGEVMAIERNLEAA IQKAAASLELKNIGTHLPELSGLSIDTLWDLAITPDDRRFFVVMELLSRSVSIDDIHE KTKIDPFFLHTFDNIIKLENRLMEAGSDLSFELLKKAKEKGFSDATIASLISKTEEEV RALRKEMGITPSFKIVDTCAAEFDAKTNYFYSTYFGETDGDISRKEKKRALIIGSGPI RIGQGVEFDYSAVHGVLTLQELGFETIMINNNPETVSTDYEIADRLYFEPMTTEHIVN VAEQENIDFAIVQFGGQTAINAAEALEKAGITLLGTSFQTLDVLEDRDQFYQLLDELG LKHAKGEIAYTKEEAASKASEIGYPVLIRPSYVIGGMGMIIVDSQAQLSQLLNDEDSM PYPILIDQYVSGKEVEIDLISDGEEVFIPTYTEHIERAGVHSGDSFAILPGPSITSGL QQGMKDAAQKIARKLSFKGIMNIQFVIDNGNILVLEVNPRASRTVPVVSKVMGVPMIP LATRLLAGASLKDLNPAVQNHHGVAVKFPVFSSHAIQDVDVKLGPEMKSTGEGMCVAY DSNSALKKIYTRVWSQKGSIYLQNVPEDVKELAENAGFTIHEGTFASWMEQEGNSLHI NLSGSEEARKERLEAMTHGIPVFTEEETVRAFLQSGSGHPQPVSLKDLYKKEVASCTQ *" gene 1200381..1203473 /gene="carB" /locus_tag="BSU_11240" /old_locus_tag="BSU11240" CDS 1203461..1204420 /gene="argF" /locus_tag="BSU_11250" /old_locus_tag="BSU11250" /EC_number="2.1.3.3" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:3099126, 6409881, 8025667, 9346304, 16585758, 26443366" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 3099126, 6409881, 8025667, 9346304, 16585758, 26443366; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="ornithine carbamoyltransferase" /protein_id="NP_389007.1" /db_xref="EnsemblGenomes-Gn:BSU11250" /db_xref="EnsemblGenomes-Tr:CAB12966" /db_xref="GOA:P18186" /db_xref="InterPro:IPR002292" /db_xref="InterPro:IPR006130" /db_xref="InterPro:IPR006131" /db_xref="InterPro:IPR006132" /db_xref="InterPro:IPR024904" /db_xref="InterPro:IPR036901" /db_xref="SubtiList:BG10197" /db_xref="UniProtKB/Swiss-Prot:P18186" /translation="MHTVTQTSLYGKDLLTLKDLSEEDINALLAEAGELKQNKIQPIF HGKTLAMIFEKSSTRTRVSFEAGMAQLGGSALFLSQKDLQLGRGETVADTAKVLSGYV DAIMIRTFEHEKVEELAKEADIPVINGLTDKYHPCQALADLLTIKEIKGKLKGVKVAY IGDGNNVAHSLMIGCAKMGCDISIASPKGYEVLDEAAEAAKTYALQSGSSVTLTDDPI EAVKDADVIYSDVFTSMGQEAEEQERLAVFAPYQVNAALVSHAKPDYTFLHCLPAHRE EEVTAEIIDGPNSAVFQQAENRLHVQKALLKAILYKGESSKNC*" gene 1203461..1204420 /gene="argF" /locus_tag="BSU_11250" /old_locus_tag="BSU11250" downshifts 1204383 /Source="Nicolas_upshifts" /id="D609" /incds=0 /nref=141 /ntot=268 /MaxReadThrough="4.29547" /MaxDrop="7.69347" /score="22.2660758" /energy="-11.1" /TU="U899" /idTUdmin="U899" /TUdmin="-305" /isTUend="FALSE" S_feature complement(1204423..1204697) /Source="Nicolas_S_feature" /locus_tag="new_1204423_1204697_c" /HighExp="G135, G180, Cold, LBGexp, G150, B60, LoTm, Paraq, Oxctl, H2O2" /AntisenseName="yjzC" /AntisenseCor="-0.37122740772860502" /AntisenseRegPval="-9.5" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S399" promotor_-35 1204448..1204454 /Source="Nicolas_upshift_promotors" /id="U901" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=943 /SigmaFactorBS="agcagtttttttgatggcAACATATtcacagccgcttagGCG CATACTACAgcaaaaaggaaaaggaggaaaaacagtgggacagcagcaccaattccgg c" /listShort="yjzC" /GFF_Attribute="listLong" /label="promotor_-35" downshifts complement(1204456) /Source="Nicolas_upshifts" /id="D610" /incds=0 /nref=33 /ntot=166 /MaxReadThrough="1.19008" /MaxDrop="5.22155" /score="16.2777759" /energy="-11.2" /TU="NA" /idTUdmin="U902" /TUdmin=0 /isTUend="TRUE" promotor_-10 1204469..1204480 /Source="Nicolas_upshift_promotors" /id="U901" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=943 /SigmaFactorBS="agcagtttttttgatggcAACATATtcacagccgcttagGCG CATACTACAgcaaaaaggaaaaggaggaaaaacagtgggacagcagcaccaattccgg c" /listShort="yjzC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1204490 /Source="Nicolas_upshifts" /id="U901" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=943 /SigmaFactorBS="agcagtttttttgatggcAACATATtcacagccgcttagGCG CATACTACAgcaaaaaggaaaaggaggaaaaacagtgggacagcagcaccaattccgg c" /listShort="yjzC" /GFF_Attribute="listLong" CDS 1204506..1204685 /gene="yjzC" /locus_tag="BSU_11260" /old_locus_tag="BSU11260" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 25859258" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_389008.1" /db_xref="EnsemblGenomes-Gn:BSU11260" /db_xref="EnsemblGenomes-Tr:CAB12967" /db_xref="InterPro:IPR025549" /db_xref="SubtiList:BG13223" /db_xref="UniProtKB/Swiss-Prot:O34585" /translation="MGQQHQFRPGQKAPNNGVYVEIGETGSMVKNPQKVHLSAGEMFP ETSNHNRLWTYKRKP*" gene 1204506..1204685 /gene="yjzC" /locus_tag="BSU_11260" /old_locus_tag="BSU11260" downshifts 1204695 /Source="Nicolas_upshifts" /id="D611" /incds=0 /nref=19 /ntot=53 /MaxReadThrough="0.25116" /MaxDrop="5.67653" /score="4.8153862" /energy="-10.9" /TU="NA" /idTUdmin="U899" /TUdmin=7 /isTUend="TRUE" CDS complement(1204731..1204916) /gene="yjzD" /locus_tag="BSU_11270" /old_locus_tag="BSU11270" /function="16.13: Shape" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:19775244" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 19775244; Product type f: factor" /codon_start=1 /transl_table=11 /product="forespore targeted protein" /protein_id="NP_389009.1" /db_xref="EnsemblGenomes-Gn:BSU11270" /db_xref="EnsemblGenomes-Tr:CAB12968" /db_xref="GOA:O34713" /db_xref="InterPro:IPR021324" /db_xref="SubtiList:BG13224" /db_xref="UniProtKB/Swiss-Prot:O34713" /translation="MRYIIAFIWTFLLSHMACYLVASMNSVTYNFKTSSVIAVVLYVL IMVLAEIMPMNKNASQH*" gene complement(1204731..1204916) /gene="yjzD" /locus_tag="BSU_11270" /old_locus_tag="BSU11270" downshifts complement(1204742) /Source="Nicolas_upshifts" /id="D612" /incds=0 /nref=215 /ntot=261 /MaxReadThrough="3.91391" /MaxDrop="6.26103" /score="9.62656276" /energy="-10.9" /TU="U902" /idTUdmin="U902" /TUdmin="-286" /isTUend="FALSE" promotor_-10 complement(1204945..1204964) /Source="Nicolas_upshift_promotors" /id="U902" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.94005994005994" /psig=1 /xcortree=3093 /SigmaFactorBS="atcagactcttttgtcacctcactttctgctaaaattggaTT CCCCCTtcgctttttgTATGGTATGATAACTTTTAGaatagaatgagaaggacgaggt g" /listShort="yjzD, S399" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1204962) /Source="Nicolas_upshifts" /id="U902" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.94005994005994" /psig=1 /xcortree=3093 /SigmaFactorBS="atcagactcttttgtcacctcactttctgctaaaattggaTT CCCCCTtcgctttttgTATGGTATGATAACTTTTAGaatagaatgagaaggacgaggt g" /listShort="yjzD, S399" /GFF_Attribute="listLong" promotor_-35 complement(1204975..1204982) /Source="Nicolas_upshift_promotors" /id="U902" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.94005994005994" /psig=1 /xcortree=3093 /SigmaFactorBS="atcagactcttttgtcacctcactttctgctaaaattggaTT CCCCCTtcgctttttgTATGGTATGATAACTTTTAGaatagaatgagaaggacgaggt g" /listShort="yjzD, S399" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1205017..1205023 /Source="Nicolas_upshift_promotors" /id="U903" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.972027972027972" /psig=1 /xcortree=3055 /SigmaFactorBS="gaatccaattttagcagaaagtgaggtgacaaaagagTCTGA TTcgtcacactttAATGGTAAAATATAAAACGTcaatcagtataatagccaaaaatgt a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1205035..1205054 /Source="Nicolas_upshift_promotors" /id="U903" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.972027972027972" /psig=1 /xcortree=3055 /SigmaFactorBS="gaatccaattttagcagaaagtgaggtgacaaaagagTCTGA TTcgtcacactttAATGGTAAAATATAAAACGTcaatcagtataatagccaaaaatgt a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1205040 /Source="Nicolas_upshifts" /id="U903" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.972027972027972" /psig=1 /xcortree=3055 /SigmaFactorBS="gaatccaattttagcagaaagtgaggtgacaaaagagTCTGA TTcgtcacactttAATGGTAAAATATAAAACGTcaatcagtataatagccaaaaatgt a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 1205097..1205106 /Source="Nicolas_upshift_promotors" /id="U904" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.956043956043956" /psig="0.956043956043956" /xcortree=1435 /SigmaFactorBS="ataaaacgtcaatcagtataatagccaaaaatgtaaaaggct aggactttaCCTTATTCGTttcttttctattTACATAAGATAGCGTGAGATgaagtgt g" /listShort="yjaU, yjaV, med" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 1205106 /Source="Nicolas_upshifts" /id="U904" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.956043956043956" /psig="0.956043956043956" /xcortree=1435 /SigmaFactorBS="ataaaacgtcaatcagtataatagccaaaaatgtaaaaggct aggactttaCCTTATTCGTttcttttctattTACATAAGATAGCGTGAGATgaagtgt g" /listShort="yjaU, yjaV, med" /GFF_Attribute="listLong" promotor_-10 1205119..1205138 /Source="Nicolas_upshift_promotors" /id="U904" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.956043956043956" /psig="0.956043956043956" /xcortree=1435 /SigmaFactorBS="ataaaacgtcaatcagtataatagccaaaaatgtaaaaggct aggactttaCCTTATTCGTttcttttctattTACATAAGATAGCGTGAGATgaagtgt g" /listShort="yjaU, yjaV, med" /GFF_Attribute="listLong" /label="promotor_-10" CDS 1205165..1205899 /gene="yjaU" /locus_tag="BSU_11280" /old_locus_tag="BSU11280" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 18582593" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_389010.1" /db_xref="EnsemblGenomes-Gn:BSU11280" /db_xref="EnsemblGenomes-Tr:CAB12969" /db_xref="InterPro:IPR029058" /db_xref="SubtiList:BG13124" /db_xref="UniProtKB/Swiss-Prot:O35001" /translation="MGITERYFQLGTEHNVIHLPYRPNGFGIFILGDRTHFVGHDSSF WQQHYGRNQLLSMLMNEGYTLFNSNLFGRHWGAEKAVTYAKQLIHSVLKQEILNPKIH ILAEGMGALVADELLRFSPDHIRSAAMLNPCLDLQAHYESEKENKFFYKQFLKEVSKS YGISEKEAEAIRYKTIQSYPSGVPVHIWQRMTGAPYPYSVHAEVFKEKQQKQGSPVDM TFHLFEHPSRIYASICKFFHSHEKEL*" gene 1205165..1205899 /gene="yjaU" /locus_tag="BSU_11280" /old_locus_tag="BSU11280" S_feature complement(1205658..1206260) /Source="Nicolas_S_feature" /locus_tag="new_1205658_1206260_c" /HighExp="S8, S6, S7, C30, BT, S4, S5, Pyr, S3, C90" /AntisenseName="yjaV" /AntisenseCor="0.66207512383157796" /AntisenseRegPval="-34.6" /CDS_PredictionProba="NA" /TUshortSig="Sig-" /TUshortPSig="0.468" /TUlongSig="NA" /TUlongPSig="NA" /label="S400" promotor_-35 1205880..1205885 /Source="Nicolas_upshift_promotors" /id="U905" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1036 /SigmaFactorBS="atccaagcagaatttatgcatcaatttgcaaattctttcata GTCATGaaaaagaattatagaGAATATAATGACAACAGCCttctcttttgcggaggct g" /listShort="yjaV, med, comZ" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 1205898 /Source="Nicolas_upshifts" /id="D613" /incds=0 /nref=6 /ntot=47 /MaxReadThrough="5.56163" /MaxDrop="4.5381" /score="1.90624641" /energy="-10" /TU="U904,U905" /idTUdmin="U904" /TUdmin="-945" /isTUend="FALSE" upshifts 1205898 /Source="Nicolas_upshifts" /id="U905" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1036 /SigmaFactorBS="atccaagcagaatttatgcatcaatttgcaaattctttcata GTCATGaaaaagaattatagaGAATATAATGACAACAGCCttctcttttgcggaggct g" /listShort="yjaV, med, comZ" /GFF_Attribute="listLong" promotor_-10 1205901..1205919 /Source="Nicolas_upshift_promotors" /id="U905" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1036 /SigmaFactorBS="atccaagcagaatttatgcatcaatttgcaaattctttcata GTCATGaaaaagaattatagaGAATATAATGACAACAGCCttctcttttgcggaggct g" /listShort="yjaV, med, comZ" /GFF_Attribute="listLong" /label="promotor_-10" CDS 1205981..1206538 /gene="yjaV" /locus_tag="BSU_11290" /old_locus_tag="BSU11290" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 14523133; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative NAD(P) binding enzyme" /protein_id="NP_389011.2" /db_xref="EnsemblGenomes-Gn:BSU11290" /db_xref="EnsemblGenomes-Tr:CAB12970" /db_xref="SubtiList:BG13125" /db_xref="UniProtKB/Swiss-Prot:O34959" /translation="MESTLIVGADEFFGLSLCERMMDEGIHVDVVLAETEDKMRQMYL EERLMWLGRNELFRQLEHIGDQNYDTICIQFGSFLPLDQYDSPYILVYEEDRKEWDKR EKTGSEKTVILPKMYGPWKEETEEDGYYTNDVADELLRFLLEPSRHSKDQLFELQVTE KTSKEEAKTKIIEWKRQFSSIFDKY*" gene 1205981..1206538 /gene="yjaV" /locus_tag="BSU_11290" /old_locus_tag="BSU11290" promotor_-10 complement(1206240..1206259) /Source="Nicolas_upshift_promotors" /id="U906" /multdbtbs="-" /comp="M5" /sig="Sig-" /pcomp="0.467532467532468" /psig="0.467532467532468" /xcortree=771 /SigmaFactorBS="gcaggatcacggttttttccgagcctgttttttcacgtttat CCCATtcttttcggtcttcTTCATATACTAAAATATAAGgagaatcatattggtctaa a" /listShort="S400" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1206260) /Source="Nicolas_upshifts" /id="U906" /multdbtbs="-" /comp="M5" /sig="Sig-" /pcomp="0.467532467532468" /psig="0.467532467532468" /xcortree=771 /SigmaFactorBS="gcaggatcacggttttttccgagcctgttttttcacgtttat CCCATtcttttcggtcttcTTCATATACTAAAATATAAGgagaatcatattggtctaa a" /listShort="S400" /GFF_Attribute="listLong" promotor_-35 complement(1206274..1206278) /Source="Nicolas_upshift_promotors" /id="U906" /multdbtbs="-" /comp="M5" /sig="Sig-" /pcomp="0.467532467532468" /psig="0.467532467532468" /xcortree=771 /SigmaFactorBS="gcaggatcacggttttttccgagcctgttttttcacgtttat CCCATtcttttcggtcttcTTCATATACTAAAATATAAGgagaatcatattggtctaa a" /listShort="S400" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1206545..1206552 /Source="Nicolas_upshift_promotors" /id="U907" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.689310689310689" /psig=1 /xcortree=2121 /SigmaFactorBS="caattttcgacaaatattaagaaaaaCCTTCCATgtttcgag ttttctAGATACAATAAACGTATAAAaataatacatgttatagcttgtcaaaaggagt t" /listShort="med, comZ, S401" /listLong="fabHA, fabF" /label="promotor_-35" promotor_-10 1206567..1206586 /Source="Nicolas_upshift_promotors" /id="U907" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.689310689310689" /psig=1 /xcortree=2121 /SigmaFactorBS="caattttcgacaaatattaagaaaaaCCTTCCATgtttcgag ttttctAGATACAATAAACGTATAAAaataatacatgttatagcttgtcaaaaggagt t" /listShort="med, comZ, S401" /listLong="fabHA, fabF" /label="promotor_-10" upshifts 1206579 /Source="Nicolas_upshifts" /id="U907" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.689310689310689" /psig=1 /xcortree=2121 /SigmaFactorBS="caattttcgacaaatattaagaaaaaCCTTCCATgtttcgag ttttctAGATACAATAAACGTATAAAaataatacatgttatagcttgtcaaaaggagt t" /listShort="med, comZ, S401" /listLong="fabHA, fabF" CDS 1206629..1207582 /gene="med" /locus_tag="BSU_11300" /old_locus_tag="BSU11300" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:1203607, 21622736, 22720735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1203607, 21622736, 22720735; Product type lp: lipoprotein" /codon_start=1 /transl_table=11 /product="positive regulator of comK" /protein_id="NP_389012.2" /db_xref="EnsemblGenomes-Gn:BSU11300" /db_xref="EnsemblGenomes-Tr:CAB12971" /db_xref="GOA:O32436" /db_xref="InterPro:IPR003760" /db_xref="InterPro:IPR028082" /db_xref="SubtiList:BG13126" /db_xref="UniProtKB/Swiss-Prot:O32436" /translation="MITRLVMIFSVLLLLSGCGQTPFKGKIEKVGMLFPDTINDLVWG TKGYKGLLNIQSKYNVDVYYKEGVKTEEDIINAIEDFHKRGVNLLYGHGSEYAEVFNL VGEDYPDMEFVISNAKAKADNVTSVHFSGEAMGFFGGMTAAHMSKTNQVGVIASFTWQ PEVDGFIKGAKYENPDIEVNTKYTDHWDDDTTAVKLYQKMKNEGADVVYPAGDGYNVP VIQQIKKDGLYAIGYVTDQSDLGENTVLTSTVQNVDKAYEIIAEQFNKGTLEGGDHYY DLNTGVVEMGTFSPLVDQDFQQRIAKLIKTYNKTGELPKNE*" gene 1206629..1207582 /gene="med" /locus_tag="BSU_11300" /old_locus_tag="BSU11300" promotor_-35 1207246..1207250 /Source="Nicolas_upshift_promotors" /id="U908" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.924075924075924" /psig=1 /xcortree=1825 /SigmaFactorBS="tcagaaaatgaagaacgaaggcgcggaTGTTGtgtatcccgc cggagACGGGTATAATGTTCCTGTTattcagcaaatcaaaaaagacggtctttatgcc a" /listShort="comZ, S401" /listLong="fabHA, fabF" /label="promotor_-35" promotor_-10 1207266..1207285 /Source="Nicolas_upshift_promotors" /id="U908" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.924075924075924" /psig=1 /xcortree=1825 /SigmaFactorBS="tcagaaaatgaagaacgaaggcgcggaTGTTGtgtatcccgc cggagACGGGTATAATGTTCCTGTTattcagcaaatcaaaaaagacggtctttatgcc a" /listShort="comZ, S401" /listLong="fabHA, fabF" /label="promotor_-10" upshifts 1207279 /Source="Nicolas_upshifts" /id="U908" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.924075924075924" /psig=1 /xcortree=1825 /SigmaFactorBS="tcagaaaatgaagaacgaaggcgcggaTGTTGtgtatcccgc cggagACGGGTATAATGTTCCTGTTattcagcaaatcaaaaaagacggtctttatgcc a" /listShort="comZ, S401" /listLong="fabHA, fabF" CDS 1207597..1207788 /gene="comZ" /locus_tag="BSU_11310" /old_locus_tag="BSU11310" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 10940045; Product type f: factor" /codon_start=1 /transl_table=11 /product="putative late competence gene" /protein_id="NP_389013.1" /db_xref="EnsemblGenomes-Gn:BSU11310" /db_xref="EnsemblGenomes-Tr:CAB12972" /db_xref="GOA:O32437" /db_xref="InterPro:IPR024558" /db_xref="SubtiList:BG13221" /db_xref="UniProtKB/Swiss-Prot:O32437" /translation="MQHEKSLEFLQIAMKYLPEAKEQLEKSGIELSMEAIQPFMNLFT TVMAEAYELGKSDAKSETE*" gene 1207597..1207788 /gene="comZ" /locus_tag="BSU_11310" /old_locus_tag="BSU11310" downshifts 1207767 /Source="Nicolas_upshifts" /id="D614" /incds=0 /nref=32 /ntot=192 /MaxReadThrough="4.56858" /MaxDrop="3.45953" /score="-7.49795364" /energy="-10.4" /TU="U907,U908" /idTUdmin="U905" /TUdmin=0 /isTUend="TRUE" S_feature 1207812..1208152 /Source="Nicolas_S_feature" /locus_tag="new_1207812_1208152" /HighExp="H2O2, C30, G135, Paraq, G180, G150, Oxctl, Cold, dia15, LPh" /AntisenseName="yjzB" /AntisenseCor="-0.34349942363230701" /AntisenseRegPval="-8.1" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="1, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S401" CDS complement(1207818..1208057) /gene="yjzB" /locus_tag="BSU_11320" /old_locus_tag="BSU11320" /experiment="publication(s) with functional evidences, PMID:16391061, 22171814, 27227299" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16391061, 22171814, 27227299; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="spore coat protein" /protein_id="NP_389014.1" /db_xref="EnsemblGenomes-Gn:BSU11320" /db_xref="EnsemblGenomes-Tr:CAB12973" /db_xref="SubtiList:BG13222" /db_xref="UniProtKB/Swiss-Prot:O34891" /translation="MQLDVFSRMMFGDAAKPTEEKEEEQQEEVSQVSQTNDEETINYM HIMDQIGSIMNSLDQIKPALKELAPMLSAIKKKIM*" gene complement(1207818..1208057) /gene="yjzB" /locus_tag="BSU_11320" /old_locus_tag="BSU11320" downshifts complement(1207834) /Source="Nicolas_upshifts" /id="D615" /incds=0 /nref=21 /ntot=48 /MaxReadThrough="1.43519" /MaxDrop="5.47891" /score="-7.75082002" /energy="-10.4" /TU="NA" /idTUdmin="U909" /TUdmin="-13" /isTUend="TRUE" promotor_-10 complement(1208070..1208089) /Source="Nicolas_upshift_promotors" /id="U909" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=1358 /SigmaFactorBS="ctaattctatcctattttttttcacatggcaatatattcGTC TAAACTAtcagttcatcttaCTCATAGAGTATGGTATATGgaaaggaggcgtatgcag t" /listShort="yjzB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1208091) /Source="Nicolas_upshifts" /id="U909" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=1358 /SigmaFactorBS="ctaattctatcctattttttttcacatggcaatatattcGTC TAAACTAtcagttcatcttaCTCATAGAGTATGGTATATGgaaaggaggcgtatgcag t" /listShort="yjzB" /GFF_Attribute="listLong" promotor_-35 complement(1208103..1208112) /Source="Nicolas_upshift_promotors" /id="U909" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=1358 /SigmaFactorBS="ctaattctatcctattttttttcacatggcaatatattcGTC TAAACTAtcagttcatcttaCTCATAGAGTATGGTATATGgaaaggaggcgtatgcag t" /listShort="yjzB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1208118..1208125 /Source="Nicolas_upshift_promotors" /id="U910" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.858141858141858" /psig=1 /xcortree=2188 /SigmaFactorBS="atgaactgatagtttagacgaataTATTGCCAtgtgaaaaaa aataGGATAGAATTAGTACCTGATactaataattgatcacaacctgattgatcttcta a" /listShort="fabHA, fabF" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1208140..1208159 /Source="Nicolas_upshift_promotors" /id="U910" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.858141858141858" /psig=1 /xcortree=2188 /SigmaFactorBS="atgaactgatagtttagacgaataTATTGCCAtgtgaaaaaa aataGGATAGAATTAGTACCTGATactaataattgatcacaacctgattgatcttcta a" /listShort="fabHA, fabF" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1208154 /Source="Nicolas_upshifts" /id="U910" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.858141858141858" /psig=1 /xcortree=2188 /SigmaFactorBS="atgaactgatagtttagacgaataTATTGCCAtgtgaaaaaa aataGGATAGAATTAGTACCTGATactaataattgatcacaacctgattgatcttcta a" /listShort="fabHA, fabF" /GFF_Attribute="listLong" CDS 1208222..1209160 /gene="fabHA" /locus_tag="BSU_11330" /old_locus_tag="BSU11330" /EC_number="2.3.1.180" /EC_number="2.3.1.38" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:10629181, 11959561, 21542858, 25196128" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10629181, 11959561, 21542858, 25196128; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="beta-ketoacyl-acyl carrier protein synthase III 1" /protein_id="NP_389015.1" /db_xref="EnsemblGenomes-Gn:BSU11330" /db_xref="EnsemblGenomes-Tr:CAB12974" /db_xref="GOA:O34746" /db_xref="InterPro:IPR004655" /db_xref="InterPro:IPR013747" /db_xref="InterPro:IPR013751" /db_xref="InterPro:IPR016039" /db_xref="SubtiList:BG13127" /db_xref="UniProtKB/Swiss-Prot:O34746" /translation="MKAGILGVGRYIPEKVLTNHDLEKMVETSDEWIRTRTGIEERRI AADDVFSSHMAVAAAKNALEQAEVAAEDLDMILVATVTPDQSFPTVSCMIQEQLGAKK ACAMDISAACAGFMYGVVTGKQFIESGTYKHVLVVGVEKLSSITDWEDRNTAVLFGDG AGAAVVGPVSDDRGILSFELGADGTGGQHLYLNEKRHTIMNGREVFKFAVRQMGESCV NVIEKAGLSKEDVDFLIPHQANIRIMEAARERLELPVEKMSKTVHKYGNTSAASIPIS LVEELEAGKIKDGDVVVMVGFGGGLTWGAIAIRWGR*" gene 1208222..1209160 /gene="fabHA" /locus_tag="BSU_11330" /old_locus_tag="BSU11330" promotor_-35 1208299..1208308 /Source="Nicolas_upshift_promotors" /id="U911" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp="0.978021978021978" /psig="0.978021978021978" /xcortree=1791 /SigmaFactorBS="tcctgagaaggttttaacaaatcatgatcttgaaaaaatggt TGAAACTTCTgacgagtggatTCGTACAAGAACAGGAatagaagaaagaagaatcgca g" /listShort="fabF" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 1208317 /Source="Nicolas_upshifts" /id="U911" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp="0.978021978021978" /psig="0.978021978021978" /xcortree=1791 /SigmaFactorBS="tcctgagaaggttttaacaaatcatgatcttgaaaaaatggt TGAAACTTCTgacgagtggatTCGTACAAGAACAGGAatagaagaaagaagaatcgca g" /listShort="fabF" /GFF_Attribute="listLong" promotor_-10 1208320..1208335 /Source="Nicolas_upshift_promotors" /id="U911" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp="0.978021978021978" /psig="0.978021978021978" /xcortree=1791 /SigmaFactorBS="tcctgagaaggttttaacaaatcatgatcttgaaaaaatggt TGAAACTTCTgacgagtggatTCGTACAAGAACAGGAatagaagaaagaagaatcgca g" /listShort="fabF" /GFF_Attribute="listLong" /label="promotor_-10" CDS 1209183..1210424 /gene="fabF" /locus_tag="BSU_11340" /old_locus_tag="BSU11340" /EC_number="2.3.1.41" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:11325930, 12682299, 16436705, 18384517, 21542858, 28196402" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11325930, 12682299, 16436705, 18384517, 21542858, 28196402; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="beta-ketoacyl-acyl carrier protein synthase II (involved in pimelate synthesis)" /protein_id="NP_389016.1" /db_xref="EnsemblGenomes-Gn:BSU11340" /db_xref="EnsemblGenomes-Tr:CAB12975" /db_xref="GOA:O34340" /db_xref="InterPro:IPR014030" /db_xref="InterPro:IPR014031" /db_xref="InterPro:IPR016039" /db_xref="InterPro:IPR017568" /db_xref="InterPro:IPR018201" /db_xref="InterPro:IPR020841" /db_xref="PDB:4LS5" /db_xref="PDB:4LS6" /db_xref="PDB:4LS7" /db_xref="PDB:4LS8" /db_xref="SubtiList:BG13128" /db_xref="UniProtKB/Swiss-Prot:O34340" /translation="MTKKRVVVTGLGALSPLGNDVDTSWNNAINGVSGIGPITRVDAE EYPAKVAAELKDFNVEDYMDKKEARKMDRFTQYAVVAAKMAVEDADLNITDEIAPRVG VWVGSGIGGLETLESQFEIFLTKGPRRVSPFFVPMMIPDMATGQISIALGAKGVNSCT VTACATGTNSIGDAFKVIQRGDADVMVTGGTEAPLTRMSFAGFSANKALSTNPDPKTA SRPFDKNRDGFVMGEGAGIIVLEELEHALARGAKIYGEIVGYGSTGDAYHITAPAQDG EGGARAMQEAIKDAGIAPEEIDYINAHGTSTYYNDKYETMAIKTVFGEHAHKLAVSST KSMTGHLLGAAGGIEAIFSILAIKEGVIPPTINIQTPDEECDLDYVPDEARRQELNYV LSNSLGFGGHNATLIFKKYQS*" gene 1209183..1210424 /gene="fabF" /locus_tag="BSU_11340" /old_locus_tag="BSU11340" promotor_-10 complement(1209397..1209415) /Source="Nicolas_upshift_promotors" /id="U912" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.813186813186813" /psig="0.813186813186813" /xcortree=777 /SigmaFactorBS="cggtaatgttaagatctgcatcttcaaccGCCATTttcgcag ccacaaccGCATATTGTGTAAAGCGGTccatttttctggcttcttttttatccatata a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1209405) /Source="Nicolas_upshifts" /id="U912" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.813186813186813" /psig="0.813186813186813" /xcortree=777 /SigmaFactorBS="cggtaatgttaagatctgcatcttcaaccGCCATTttcgcag ccacaaccGCATATTGTGTAAAGCGGTccatttttctggcttcttttttatccatata a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(1209431..1209436) /Source="Nicolas_upshift_promotors" /id="U912" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.813186813186813" /psig="0.813186813186813" /xcortree=777 /SigmaFactorBS="cggtaatgttaagatctgcatcttcaaccGCCATTttcgcag ccacaaccGCATATTGTGTAAAGCGGTccatttttctggcttcttttttatccatata a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 1210275 /Source="Nicolas_upshifts" /id="D616" /incds=1 /nref=1 /ntot=89 /MaxReadThrough="7.03006" /MaxDrop="2.1101" /score="54.6350161" /energy="-18.5" /TU="U910,U911" /idTUdmin="U911" /TUdmin="-132" /isTUend="FALSE" downshifts 1210408 /Source="Nicolas_upshifts" /id="D617" /incds=0 /nref=246 /ntot=274 /MaxReadThrough="0.58964" /MaxDrop="7.80446" /score="54.6350161" /energy="-18.5" /TU="NA" /idTUdmin="U911" /TUdmin=1 /isTUend="TRUE" promotor_-35 1210449..1210458 /Source="Nicolas_upshift_promotors" /id="U913" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1338 /SigmaFactorBS="tatcaatcataatcaagccaaaccggctgcccttaaAGGGTA GCCGgttttttttgtgTGCATAGGATTAAAAGAGGAggcgatcacatgagtgtagaac a" /listShort="yjaZ, S402, S403, appD, appF" /listLong="S404, appA, appA, appB, appC" /label="promotor_-35" promotor_-10 1210471..1210490 /Source="Nicolas_upshift_promotors" /id="U913" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1338 /SigmaFactorBS="tatcaatcataatcaagccaaaccggctgcccttaaAGGGTA GCCGgttttttttgtgTGCATAGGATTAAAAGAGGAggcgatcacatgagtgtagaac a" /listShort="yjaZ, S402, S403, appD, appF" /listLong="S404, appA, appA, appB, appC" /label="promotor_-10" upshifts 1210473 /Source="Nicolas_upshifts" /id="U913" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1338 /SigmaFactorBS="tatcaatcataatcaagccaaaccggctgcccttaaAGGGTA GCCGgttttttttgtgTGCATAGGATTAAAAGAGGAggcgatcacatgagtgtagaac a" /listShort="yjaZ, S402, S403, appD, appF" /listLong="S404, appA, appA, appB, appC" promotor_-35 1210485..1210493 /Source="Nicolas_upshift_promotors" /id="U914" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=544 /SigmaFactorBS="cggttttttttgtgtgcataggattaaaAGAGGAGGCgatca catgagTGTAGAACAAACATATAGCtggctcaggaaggccggttcaatagatgatttg g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" CDS 1210500..1211285 /gene="yjaZ" /locus_tag="BSU_11350" /old_locus_tag="BSU11350" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_389017.1" /db_xref="EnsemblGenomes-Gn:BSU11350" /db_xref="EnsemblGenomes-Tr:CAB12992" /db_xref="InterPro:IPR018728" /db_xref="SubtiList:BG13129" /db_xref="UniProtKB/Swiss-Prot:O31596" /translation="MSVEQTYSWLRKAGSIDDLAHYIIPLFSGAEKKNWKGILGHLQH HGMFKNIKEGIQTVSKLKEKGFYGHIQKEEQYLKNKWQGPDVPIVTLPVDERNRRIRL EFGSKSGLAFQDKMFLFLSSDLDFGSVSALMTHEYHHVCRLGHLTKEEKDVTLLDTII MEGLAEYAVYERFGRSQTAEWTTWYTPEQLQALYEKKIAPHRDIKRDNRLFPQLLFGK GYQPKMLGYAVGFNIVKKYLTASKASTADGLSIPAETFLDAML*" gene 1210500..1211285 /gene="yjaZ" /locus_tag="BSU_11350" /old_locus_tag="BSU11350" promotor_-10 1210505..1210523 /Source="Nicolas_upshift_promotors" /id="U914" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=544 /SigmaFactorBS="cggttttttttgtgtgcataggattaaaAGAGGAGGCgatca catgagTGTAGAACAAACATATAGCtggctcaggaaggccggttcaatagatgatttg g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1210517 /Source="Nicolas_upshifts" /id="U914" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=544 /SigmaFactorBS="cggttttttttgtgtgcataggattaaaAGAGGAGGCgatca catgagTGTAGAACAAACATATAGCtggctcaggaaggccggttcaatagatgatttg g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" S_feature 1211286..1211370 /Source="Nicolas_S_feature" /locus_tag="new_1211286_1211370" /HighExp="S6, S5, S8, S7, BT, S4, S3, B36, T5.0H, T4.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigK" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S402" promotor_-10 complement(1211302..1211320) /Source="Nicolas_upshift_promotors" /id="U915" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.838161838161838" /psig="0.838161838161838" /xcortree=1001 /SigmaFactorBS="tttatagttgtatattattacaatcattttgcaaaatcaAGA ATTttttaggataaatgTAATATTATTAATGAAATTccattattttatccttttaaag c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1211319) /Source="Nicolas_upshifts" /id="U915" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.838161838161838" /psig="0.838161838161838" /xcortree=1001 /SigmaFactorBS="tttatagttgtatattattacaatcattttgcaaaatcaAGA ATTttttaggataaatgTAATATTATTAATGAAATTccattattttatccttttaaag c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(1211335..1211340) /Source="Nicolas_upshift_promotors" /id="U915" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.838161838161838" /psig="0.838161838161838" /xcortree=1001 /SigmaFactorBS="tttatagttgtatattattacaatcattttgcaaaatcaAGA ATTttttaggataaatgTAATATTATTAATGAAATTccattattttatccttttaaag c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1211338..1211345 /Source="Nicolas_upshift_promotors" /id="U916" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.98001998001998" /psig="0.999000999001" /xcortree=2876 /SigmaFactorBS="ataatattacatttatcctaaaaaatTCTTGATTttgcaaaa tgattgTAATAATATACAACTATAAAatttttcgataattcaatattatttattattt c" /listShort="S403, appD, appF, S404, appA, appA, appB, appC, S405, yjbA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1211360..1211379 /Source="Nicolas_upshift_promotors" /id="U916" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.98001998001998" /psig="0.999000999001" /xcortree=2876 /SigmaFactorBS="ataatattacatttatcctaaaaaatTCTTGATTttgcaaaa tgattgTAATAATATACAACTATAAAatttttcgataattcaatattatttattattt c" /listShort="S403, appD, appF, S404, appA, appA, appB, appC, S405, yjbA" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 1211372..1211476 /Source="Nicolas_S_feature" /locus_tag="new_1211372_1211476" /HighExp="LoTm, T4.0H, T3.0H, T5.0H, T3.30H, T2.30H, M9-stat, S1, T2.0H, T1.30H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigK" /TUshortPSig="0.999, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S403" upshifts 1211372 /Source="Nicolas_upshifts" /id="U916" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.98001998001998" /psig="0.999000999001" /xcortree=2876 /SigmaFactorBS="ataatattacatttatcctaaaaaatTCTTGATTttgcaaaa tgattgTAATAATATACAACTATAAAatttttcgataattcaatattatttattattt c" /listShort="S403, appD, appF, S404, appA, appA, appB, appC, S405, yjbA" /GFF_Attribute="listLong" CDS 1211477..1212463 /gene="appD" /locus_tag="BSU_11360" /old_locus_tag="BSU11360" /EC_number="3.6.3.-" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:7997159, 25755103, 26728191" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7997159, 25755103, 26728191; Product type t: transporter" /codon_start=1 /transl_table=11 /product="oligopeptide ABC transporter (ATP-binding protein)" /protein_id="NP_389018.1" /db_xref="EnsemblGenomes-Gn:BSU11360" /db_xref="EnsemblGenomes-Tr:CAB12993" /db_xref="GOA:P42064" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR013563" /db_xref="InterPro:IPR017871" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG11085" /db_xref="UniProtKB/Swiss-Prot:P42064" /translation="MSTLLEVNNLKTYFFRKKEPIPAVDGVDFHISKGETVALVGESG SGKSITSLSIMGLVQSSGGKIMDGSIKLEDKDLTSFTENDYCKIRGNEVSMIFQEPMT SLNPVLTIGEQITEVLIYHKNMKKKEARQRAVELLQMVGFSRAEQIMKEYPHRLSGGM RQRVMIAIALSCNPKLLIADEPTTALDVTIQAQVLELMKDLCQKFNTSILLITHDLGV VSEAADRVIVMYCGQVVENATVDDLFLEPLHPYTEGLLTSIPVIDGEIDKLNAIKGSV PTPDNLPPGCRFAPRCPKAMDKCWTNQPSLLTHKSGRTVRCFLYEEEGAEQS*" gene 1211477..1212463 /gene="appD" /locus_tag="BSU_11360" /old_locus_tag="BSU11360" CDS 1212460..1213449 /gene="appF" /locus_tag="BSU_11370" /old_locus_tag="BSU11370" /EC_number="3.6.3.-" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:7997159, 25755103, 26728191, 22720735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7997159, 25755103, 26728191, 22720735; Product type t: transporter" /codon_start=1 /transl_table=11 /product="oligopeptide ABC transporter (ATP-binding protein)" /protein_id="NP_389019.2" /db_xref="EnsemblGenomes-Gn:BSU11370" /db_xref="EnsemblGenomes-Tr:CAB12994" /db_xref="GOA:P42065" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR013563" /db_xref="InterPro:IPR017871" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG11086" /db_xref="UniProtKB/Swiss-Prot:P42065" /translation="MTAANQETILELRDVKKYFPIRSGLFQRKVGDVKAVDGVSFSLK KGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSEEKLRKSVRKNIQM VFQDPFASLNPRKTLRSIIKEPFNTHNMYTMRERNEKVEELLARVGLHPSFAGRYPHE FSGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFIS HDLSVVRHISDRVGVMYLGKMMELTGKHELYDNPLHPYTQALLSSVPVTRKRGSVKRE RIVLKGELPSPANPPKGCVFHTRCPVAKPICKEQIPEFKEAAPSHFVACHLYS*" gene 1212460..1213449 /gene="appF" /locus_tag="BSU_11370" /old_locus_tag="BSU11370" misc_feature 1213455..1213461 /Source="Nicolas_upshift_promotors" /id="U917" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.375624375624376" /psig="0.062937062937063" /xcortree=2877 /SigmaFactorBS="ttaaagaagctgctcccagccactttgtggcttgtcaccttt atagctaatgttgCCCGCACagctttgagagggggtatgcacactacataaacaacag c" /listShort="S404, appA, appA, appB, appC, S405, yjbA" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" S_feature 1213460..1213536 /Source="Nicolas_S_feature" /locus_tag="new_1213460_1213536" /HighExp="T2.0H, S1, M9-stat, T5.0H, T3.0H, T1.30H, S2, M0t90, T2.30H, BT" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="Sig-, SigA" /TUshortPSig="0.0629, 0.999" /TUlongSig="SigK" /TUlongPSig=1 /label="S404" upshifts 1213460 /Source="Nicolas_upshifts" /id="U917" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.375624375624376" /psig="0.062937062937063" /xcortree=2877 /SigmaFactorBS="ttaaagaagctgctcccagccactttgtggcttgtcaccttt atagctaatgttgCCCGCACagctttgagagggggtatgcacactacataaacaacag c" /listShort="S404, appA, appA, appB, appC, S405, yjbA" /GFF_Attribute="listLong" CDS 1213537..1214028 /gene="appAn" /locus_tag="BSU_11381" /old_locus_tag="BSU11381" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function; PubMedId : 15588833, 25355936; Product type rc: receptor" /pseudo /codon_start=1 /transl_table=11 /product="oligopeptide ABC transporter (oligopeptide-binding lipoprotein); N-terminal part of AppA" /translation="MKRRKTALMMLSVLMVLAIFLSACSGSKSSNSSAKKSAGKPQQG GDLVVGSIGEPTLFNSLYSTDDASTDIENMLYSFLTKTDEKLNVKLSLAESIKELDGG LAYDVKIKKGVKFHDGKELTADDVVFTYSVPLSKDYKGERGSTYEMLKSVEKKAITKS CLS*" gene 1213537..1214028 /gene="appAn" /locus_tag="BSU_11381" /old_locus_tag="BSU11381" /pseudo CDS 1214001..1215167 /gene="appAc" /locus_tag="BSU_11382" /old_locus_tag="BSU11382" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function; PubMedId: 7997159, 15588833, 26728191; Product type lp: lipoprotein" /pseudo /codon_start=1 /transl_table=11 /product="oligopeptide ABC transporter (oligopeptide-binding lipoprotein); C-terminal part of AppA" /translation="GDYEVLFKLKYKDGNFYNNALDSTAILPKHILGNVPIADLEENE FNRKKPIGSGPFKFKEWKQGQYIKLEANDDYFEGRPYLDTVTYKVIPDANAAVAQLQA GDINFFNVPATDYKTAEKFNNLKIVTDLALSYVYIGWNEKNELFKDKKVRQALTTALD RESIVSQVLDGDGEVAYIPESPLSWNYPKDIDVPKFEYNEKKAKQMLAEAGWKDTNGD GILDKDGKKFSFTLKTNQGNKVREDIAVVVQEQLKKIGIEVKTQIVEWSALVEQMNPP NWDFDAMVMGWSLSTFPDQYDIFHSSQIKKGLNYVWYKNAEADKLMKDAKSISDRKQY SKEYEQIYQKIAEDQPYTFLYYPNNHMAMPENLEGYKYHPKRDLYNIEKWWLAK*" gene 1214001..1215167 /gene="appAc" /locus_tag="BSU_11382" /old_locus_tag="BSU11382" /pseudo downshifts 1215158 /Source="Nicolas_upshifts" /id="D618" /incds=0 /nref=1 /ntot=49 /MaxReadThrough="7.71397" /MaxDrop="3.11667" /score="-1.00317393" /energy="-13.3" /TU="U916,U917" /idTUdmin="U913" /TUdmin=1715 /isTUend="FALSE" CDS 1215243..1216193 /gene="appB" /locus_tag="BSU_11390" /old_locus_tag="BSU11390" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:7997159, 15849754, 16850406, 26728191" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7997159, 15849754, 16850406, 26728191; Product type t: transporter" /codon_start=1 /transl_table=11 /product="oligopeptide ABC transporter (permease)" /protein_id="NP_389021.2" /db_xref="EnsemblGenomes-Gn:BSU11390" /db_xref="EnsemblGenomes-Tr:CAB12996" /db_xref="GOA:P42062" /db_xref="InterPro:IPR000515" /db_xref="InterPro:IPR035906" /db_xref="SubtiList:BG11088" /db_xref="UniProtKB/Swiss-Prot:P42062" /translation="MAAYIIRRTLMSIPILLGITILSFVIMKAAPGDPMTLMMDPKIS QADREQFIEKYGLNDPQYVQYLKWLGNMVQGDFGTSIVRKGTPVSELIMARLPNTLLL MLVSTILALMISIPFGVLSAKRPYSKIDYGITFTSFIGLAIPNFWFGLILIMVLSVNL GWFPTGGVETLNTEFNIFDRIHHLILPAFVLATADMAGLTRYTRSNMLDVLNQDYIRT ARAKGFKENRVLFKHGLRNALLPVITIFGLMIPSFIGGSVVVEQIFTWPGLGKLFVDS AFQRDYPVIMAMTVISAVLVVVGNLIADILYAIVDPRIEY*" gene 1215243..1216193 /gene="appB" /locus_tag="BSU_11390" /old_locus_tag="BSU11390" CDS 1216210..1217121 /gene="appC" /locus_tag="BSU_11400" /old_locus_tag="BSU11400" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:7997159, 15849754, 16850406, 26728191" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7997159, 15849754, 16850406, 26728191; Product type t: transporter" /codon_start=1 /transl_table=11 /product="oligopeptide ABC transporter (permease)" /protein_id="NP_389022.1" /db_xref="EnsemblGenomes-Gn:BSU11400" /db_xref="EnsemblGenomes-Tr:CAB12997" /db_xref="GOA:P42063" /db_xref="InterPro:IPR000515" /db_xref="InterPro:IPR025966" /db_xref="InterPro:IPR035906" /db_xref="SubtiList:BG11089" /db_xref="UniProtKB/Swiss-Prot:P42063" /translation="MSELQTTPSPEIRLKENISKKPETMTKIFWEKFSKNKLAILGAV ILFIIIMSAVFAPLIAPYPQEQQSLLDKYKAPGLEHLMGTDKFGRDIFSRILYGARVS LLVGFASVVGSILIGTVLGALAGYFRGIVDAVIMRVVDIVLSIPDIFLLITLVTIFKP GVDKLILIFCLTGWTTTARLVRGEFLSLRSREYVLAAKTIGTKTHKIIFSHILPNALG PIIVSATLKVGSVILAESALSYLGFGIQPPIASWGNMLQDAQNFTVMIQAWWYPLFPG LFILMTVLCFNFVGDGLRDALDPKNIK*" gene 1216210..1217121 /gene="appC" /locus_tag="BSU_11400" /old_locus_tag="BSU11400" downshifts 1217135 /Source="Nicolas_upshifts" /id="D619" /incds=0 /nref=62 /ntot=188 /MaxReadThrough="5.13927" /MaxDrop="5.50153" /score="22.0028545" /energy="-11.6" /TU="U916,U917" /idTUdmin="U916" /TUdmin="-923" /isTUend="FALSE" S_feature 1217180..1217287 /Source="Nicolas_S_feature" /locus_tag="new_1217180_1217287" /HighExp="LoTm, S1, S2, BT, T3.30H, T4.0H, T5.0H, T3.0H, Glu, T2.30H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="Sig-, SigA" /TUshortPSig="0.0629, 0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S405" promotor_-35 1217260..1217265 /Source="Nicolas_upshift_promotors" /id="U918" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1160 /SigmaFactorBS="cccagtgattccagatttcctcaatctctttGGAATAatttc tctatcccttGCCTATACTGTGGACAACAgtttttataaaagtgaggggttagagatg t" /listShort="yjbA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1217281..1217299 /Source="Nicolas_upshift_promotors" /id="U918" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1160 /SigmaFactorBS="cccagtgattccagatttcctcaatctctttGGAATAatttc tctatcccttGCCTATACTGTGGACAACAgtttttataaaagtgaggggttagagatg t" /listShort="yjbA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1217289 /Source="Nicolas_upshifts" /id="U918" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1160 /SigmaFactorBS="cccagtgattccagatttcctcaatctctttGGAATAatttc tctatcccttGCCTATACTGTGGACAACAgtttttataaaagtgaggggttagagatg t" /listShort="yjbA" /GFF_Attribute="listLong" CDS 1217326..1218078 /gene="yjbA" /locus_tag="BSU_11410" /old_locus_tag="BSU11410" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 11717292, 22882546; Product type f: factor" /codon_start=1 /transl_table=11 /product="putative sporulation nucleic acid binding protein" /protein_id="NP_389023.1" /db_xref="EnsemblGenomes-Gn:BSU11410" /db_xref="EnsemblGenomes-Tr:CAB12998" /db_xref="InterPro:IPR020909" /db_xref="SubtiList:BG13130" /db_xref="UniProtKB/Swiss-Prot:O31597" /translation="MLFLHDVWVNWFEGEENGYNVCHFHEWRKEDTVELLDQVPLLRV PSVLFHYIENDLSELPKGLLEDVHQKSYIRKNHERTKLEYCFVVTDGIGILAVDTIGY TIPVRKSRLIPRQEQLVYEMVKDVEPETYEFEPKKLESSKEYHILSLAPEHVRGLTRK ERQIKQLMFMALDQLKGLKNRAEIGYWYTEWNPHMYEQIKRMSFEEIWDMLYNETIEG WSDKHLAFCENLIKGQPFFEKLWEMENESKVN*" gene 1217326..1218078 /gene="yjbA" /locus_tag="BSU_11410" /old_locus_tag="BSU11410" downshifts 1218058 /Source="Nicolas_upshifts" /id="D620" /incds=0 /nref=32 /ntot=112 /MaxReadThrough="1.07428" /MaxDrop="6.2264" /score="22.0028545" /energy="-11.6" /TU="NA" /idTUdmin="U916" /TUdmin=0 /isTUend="TRUE" CDS complement(1218113..1219105) /gene="trpS" /locus_tag="BSU_11420" /old_locus_tag="BSU11420" /EC_number="6.1.1.2" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:8950174, 10706627, 12682299, 24572018" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8950174, 10706627, 12682299, 24572018; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="tryptophanyl-tRNA synthetase" /protein_id="NP_389024.1" /db_xref="EnsemblGenomes-Gn:BSU11420" /db_xref="EnsemblGenomes-Tr:CAB12999" /db_xref="GOA:P21656" /db_xref="InterPro:IPR001412" /db_xref="InterPro:IPR002305" /db_xref="InterPro:IPR002306" /db_xref="InterPro:IPR014729" /db_xref="InterPro:IPR024109" /db_xref="PDB:3PRH" /db_xref="SubtiList:BG10799" /db_xref="UniProtKB/Swiss-Prot:P21656" /translation="MKQTIFSGIQPSGSVTLGNYIGAMKQFVELQHDYNSYFCIVDQH AITVPQDRLELRKNIRNLAALYLAVGLDPEKATLFIQSEVPAHAQAGWMMQCVAYIGE LERMTQFKDKSKGNEAVVSGLLTYPPLMAADILLYGTDLVPVGEDQKQHLELTRNLAE RFNKKYNDIFTIPEVKIPKVGARIMSLNDPLKKMSKSDPNQKAYITLLDEPKQLEKKI KSAVTDSEGIVKFDKENKPGVSNLLTIYSILGNTTIEELEAKYEGKGYGEFKGDLAEV VVNALKPIQDRYYELIESEELDRILDEGAERANRTANKMLKKMENAMGLGRKRR*" gene complement(1218113..1219105) /gene="trpS" /locus_tag="BSU_11420" /old_locus_tag="BSU11420" downshifts complement(1218134) /Source="Nicolas_upshifts" /id="D621" /incds=0 /nref=224 /ntot=255 /MaxReadThrough="1.77115" /MaxDrop="6.72647" /score="27.6275522" /energy="-11.6" /TU="U919" /idTUdmin="U919" /TUdmin="-22" /isTUend="TRUE" misc_RNA complement(1219164..1219378) /gene="tboWA" /locus_tag="BSU_misc_RNA_13" /product="T-box riboswitch specific of tryptophan tRNA" /experiment="publication(s) with functional evidences, PMID:8045882, 9098041, 10706627, 10943892, 11842119, 12165569, 12547201, 1317842" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8045882, 9098041, 10706627, 10943892, 11842119, 12165569, 12547201, 1317842; Product type n: RNA" /function="16.3: Control" gene complement(1219164..1219378) /gene="tboWA" /locus_tag="BSU_misc_RNA_13" downshifts complement(1219212) /Source="Nicolas_upshifts" /id="D622" /incds=0 /nref=37 /ntot=127 /MaxReadThrough="6.8472" /MaxDrop="5.13001" /score="25.1445248" /energy="-19" /TU="U919" /idTUdmin="U919" /TUdmin="-1100" /isTUend="FALSE" misc_feature complement(1219397..1219416) /Source="Nicolas_upshift_promotors" /id="U919" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.509490509490509" /psig="0.99100899100899" /xcortree=602 /SigmaFactorBS="tatttatattattacaattttactggaaaaaagaatgttttt tcatgatgacaaTTGGTTATAATTGATTTATAatgaagcaatcaaaagaaaagcttgc t" /listShort="NA, trpS" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(1219410) /Source="Nicolas_upshifts" /id="U919" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.509490509490509" /psig="0.99100899100899" /xcortree=602 /SigmaFactorBS="tatttatattattacaattttactggaaaaaagaatgttttt tcatgatgacaaTTGGTTATAATTGATTTATAatgaagcaatcaaaagaaaagcttgc t" /listShort="NA, trpS" /GFF_Attribute="listLong" promotor_-35 1219665..1219672 /Source="Nicolas_upshift_promotors" /id="U920" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.828171828171828" /psig=1 /xcortree=491 /SigmaFactorBS="aactaacgaagtttaaatattttaaattgataaaataaTATT GCAAtaaattatttgtttCATTATAATGAACTTGTTCActctattgttacagcttttt t" /listShort="S406, oppA, S407, oppB, oppC, oppD, oppF" /GFF_Attribute="listLong" /label="promotor_-35" S_feature 1219686..1219848 /Source="Nicolas_S_feature" /locus_tag="new_1219686_1219848" /HighExp="S1, T3.0H, T3.30H, T2.30H, T4.0H, T5.0H, LoTm, T2.0H, M40t90, T1.30H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S406" promotor_-10 1219687..1219706 /Source="Nicolas_upshift_promotors" /id="U920" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.828171828171828" /psig=1 /xcortree=491 /SigmaFactorBS="aactaacgaagtttaaatattttaaattgataaaataaTATT GCAAtaaattatttgtttCATTATAATGAACTTGTTCActctattgttacagcttttt t" /listShort="S406, oppA, S407, oppB, oppC, oppD, oppF" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1219687 /Source="Nicolas_upshifts" /id="U920" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.828171828171828" /psig=1 /xcortree=491 /SigmaFactorBS="aactaacgaagtttaaatattttaaattgataaaataaTATT GCAAtaaattatttgtttCATTATAATGAACTTGTTCActctattgttacagcttttt t" /listShort="S406, oppA, S407, oppB, oppC, oppD, oppF" /GFF_Attribute="listLong" CDS 1219849..1221486 /gene="oppA" /locus_tag="BSU_11430" /old_locus_tag="BSU11430" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:1901616, 11083832, 11401703, 12823818, 15588833, 23133654, 26176322, 22720735, 25355936" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1901616, 11083832, 11401703, 12823818, 15588833, 23133654, 26176322, 22720735, 25355936; Product type lp: lipoprotein" /codon_start=1 /transl_table=11 /product="oligopeptide ABC transporter (binding lipoprotein)" /protein_id="NP_389025.1" /db_xref="EnsemblGenomes-Gn:BSU11430" /db_xref="EnsemblGenomes-Tr:CAB13000" /db_xref="GOA:P24141" /db_xref="InterPro:IPR000914" /db_xref="InterPro:IPR023765" /db_xref="InterPro:IPR030678" /db_xref="SubtiList:BG10771" /db_xref="UniProtKB/Swiss-Prot:P24141" /translation="MKKRWSIVTLMLIFTLVLSACGFGGSGSNGEGKKDSKGKTTLNI NIKTEPFSLHPGLANDSVSGGVIRQTFEGLTRINADGEPEEGMASKIETSKDGKTYTF TIRDGVKWSNGDPVTAQDFEYAWKWALDPNNESQYAYQLYYIKGAEAANTGKGSLDDV AVKAVNDKTLKVELNNPTPYFTELTAFYTYMPINKKIAEKNKKWNTNAGDDYVSNGPF KMTAWKHSGSITLEKNDQYWDKDKVKLKKIDMVMINNNNTELKKFQAGELDWAGMPLG QLPTESLPTLKKDGSLHVEPIAGVYWYKFNTEAKPLDNVNIRKALTYSLDRQSIVKNV TQGEQIPAMAAVPPTMKGFEDNKEGYFKDNDVKTAKEYLEKGLKEMGLSKASDLPKIK LSYNTDDAHAKIAQAVQEMWKKNLGVDVELDNSEWNVYIDKLHSQDYQIGRMGWLGDF NDPINFLELFRDKNGGNNDTGWENPEFKKLLNQSQTETDKTKRAELLKKAEGIFIDEM PVAPIYFYTDTWVQDENLKGVIMPGTGEVYFRNAYFK*" gene 1219849..1221486 /gene="oppA" /locus_tag="BSU_11430" /old_locus_tag="BSU11430" downshifts 1221380 /Source="Nicolas_upshifts" /id="D623" /incds=1 /nref=8 /ntot=166 /MaxReadThrough="6.94127" /MaxDrop="3.3677" /score="-4.2761508" /energy="-15.6" /TU="U920" /idTUdmin="U916" /TUdmin=3322 /isTUend="FALSE" S_feature 1221487..1221593 /Source="Nicolas_S_feature" /locus_tag="new_1221487_1221593" /HighExp="S1, LoTm, T4.0H, BT, T3.30H, T3.0H, T5.0H, M0t90, T2.30H, T2.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S407" CDS 1221594..1222529 /gene="oppB" /locus_tag="BSU_11440" /old_locus_tag="BSU11440" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:1901616, 11401703, 15849754, 16850406, 17600541, 25355936" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1901616, 11401703, 15849754, 16850406, 17600541, 25355936; Product type t : transporter" /codon_start=1 /transl_table=11 /product="oligopeptide ABC transporter (permease)" /protein_id="NP_389026.1" /db_xref="EnsemblGenomes-Gn:BSU11440" /db_xref="EnsemblGenomes-Tr:CAB13001" /db_xref="GOA:P24138" /db_xref="InterPro:IPR000515" /db_xref="InterPro:IPR035906" /db_xref="SubtiList:BG10772" /db_xref="UniProtKB/Swiss-Prot:P24138" /translation="MLKYIGRRLVYMIITLFVIVTVTFFLMQAAPGGPFSGEKKLPPE IEANLNAHYGLDKPLFVQYVSYLKSVAMWDFGPSFKYKGQSVNDLISSGFPVSFTLGA EAILLALALGVLFGVIAALYHNKWQDYTVAILTIFGISVPSFIMAAVLQYVFSMKLGL FPVAGWDSWAYTFLPSIALASMPMAFIARLSRSSMIEVLNSDYIRTAKAKGLSRPAVT VRHAIRNALLPVVTYMGPMAAQVLTGSFIIETIFGIPGLGAHFVNSITNRDYTVIMGV TVFFSVILLLCVLIVDVLYGIIDPRIKLSKAKKGA*" gene 1221594..1222529 /gene="oppB" /locus_tag="BSU_11440" /old_locus_tag="BSU11440" promotor_-10 complement(1221637..1221656) /Source="Nicolas_upshift_promotors" /id="U921" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.508491508491508" /psig="0.97902097902098" /xcortree=1450 /SigmaFactorBS="gctttttctcacctgaaaatggcccgcccggtgctgCTTGCA TtaagaagaatgtcacAGTTACAATCACAAATAGTGtgataatcatatagactaagcg t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1221654) /Source="Nicolas_upshifts" /id="U921" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.508491508491508" /psig="0.97902097902098" /xcortree=1450 /SigmaFactorBS="gctttttctcacctgaaaatggcccgcccggtgctgCTTGCA TtaagaagaatgtcacAGTTACAATCACAAATAGTGtgataatcatatagactaagcg t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(1221672..1221678) /Source="Nicolas_upshift_promotors" /id="U921" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.508491508491508" /psig="0.97902097902098" /xcortree=1450 /SigmaFactorBS="gctttttctcacctgaaaatggcccgcccggtgctgCTTGCA TtaagaagaatgtcacAGTTACAATCACAAATAGTGtgataatcatatagactaagcg t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" CDS 1222533..1223450 /gene="oppC" /locus_tag="BSU_11450" /old_locus_tag="BSU11450" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:1901616, 11401703, 15849754, 16850406, 26782429" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1901616, 11401703, 15849754, 16850406, 26782429; Product type t : transporter" /codon_start=1 /transl_table=11 /product="oligopeptide ABC transporter (permease)" /protein_id="NP_389027.1" /db_xref="EnsemblGenomes-Gn:BSU11450" /db_xref="EnsemblGenomes-Tr:CAB13002" /db_xref="GOA:P24139" /db_xref="InterPro:IPR000515" /db_xref="InterPro:IPR025966" /db_xref="InterPro:IPR035906" /db_xref="SubtiList:BG10773" /db_xref="UniProtKB/Swiss-Prot:P24139" /translation="MQNIPKNMFEPAAANAGDAEKISKKSLSLWKDAMLRFRSNKLAM VGLIIIVLIILMAIFAPMFSRYDYSTTNLLNADKPPSKDHWFGTDDLGRDIFVRTWVG ARISIFIGVAAAVLDLLIGVIWGSISGFRGGRTDEIMMRIADILWAVPSLLMVILLMV VLPKGLFTIIIAMTITGWINMARIVRGQVLQLKNQEYVLASQTLGAKTSRLLFKHIVP NAMGSILVTMTLTVPTAIFTEAFLSYLGLGVPAPLASWGTMASDGLPALTYYPWRLFF PAGFICITMFGFNVVGDGLRDALDPKLRK*" gene 1222533..1223450 /gene="oppC" /locus_tag="BSU_11450" /old_locus_tag="BSU11450" CDS 1223455..1224531 /gene="oppD" /locus_tag="BSU_11460" /old_locus_tag="BSU11460" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:1901616, 11401703, 19202088, 22720735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1901616, 11401703, 19202088, 22720735; Product type t: transporter" /codon_start=1 /transl_table=11 /product="oligopeptide ABC transporter (ATP-binding protein)" /protein_id="NP_389028.1" /db_xref="EnsemblGenomes-Gn:BSU11460" /db_xref="EnsemblGenomes-Tr:CAB13003" /db_xref="GOA:P24136" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR013563" /db_xref="InterPro:IPR017871" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG10774" /db_xref="UniProtKB/Swiss-Prot:P24136" /translation="MIRVTRLLEVKDLAISFKTYGGEVQAIRGVNFHLDKGETLAIVG ESGSGKSVTSQAIMKLIPMPPGYFKRGEILFEGKDLVPLSEKEMQNVRGKEIGMIFQD PMTSLNPTMKVGKQITEVLFKHEKISKEAAKKRAVELLELVGIPMPEKRVNQFPHEFS GGMRQRVVIAMALAANPKLLIADEPTTALDVTIQAQILELMKDLQKKIDTSIIFITHD LGVVANVADRVAVMYAGQIVETGTVDEIFYDPRHPYTWGLLASMPTLESSGEEELTAI PGTPPDLTNPPKGDAFALRSSYAMKIDFEQEPPMFKVSDTHYVKSWLLHPDAPKVEPP EAVKAKMRKLANTFEKPVLVREVE*" gene 1223455..1224531 /gene="oppD" /locus_tag="BSU_11460" /old_locus_tag="BSU11460" CDS 1224533..1225450 /gene="oppF" /locus_tag="BSU_11470" /old_locus_tag="BSU11470" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:1901616, 7997159, 11401703, 23133654, 22720735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1901616, 7997159, 11401703, 23133654, 22720735; Product type t : transporter" /codon_start=1 /transl_table=11 /product="oligopeptide ABC transporter (ATP-binding protein)" /protein_id="NP_389029.1" /db_xref="EnsemblGenomes-Gn:BSU11470" /db_xref="EnsemblGenomes-Tr:CAB13004" /db_xref="GOA:P24137" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR013563" /db_xref="InterPro:IPR017871" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG10775" /db_xref="UniProtKB/Swiss-Prot:P24137" /translation="MTEKLLEIKHLKQHFVTPRGTVKAVDDLSFDIYKGETLGLVGES GCGKSTTGRSIIRLYEATDGEVLFNGENVHGRKSRKKLLEFNRKMQMIFQDPYASLNP RMTVADIIAEGLDIHKLAKTKKERMQRVHELLETVGLNKEHANRYPHEFSGGQRQRIG IARALAVDPEFIIADEPISALDVSIQAQVVNLMKELQKEKGLTYLFIAHDLSMVKYIS DRIGVMYFGKLVELAPADELYENPLHPYTKSLLSAIPLPDPDYERNRVRQKYDPSVHQ LKDGETMEFREVKPGHFVMCTEAEFKAFS*" gene 1224533..1225450 /gene="oppF" /locus_tag="BSU_11470" /old_locus_tag="BSU11470" downshifts 1225420 /Source="Nicolas_upshifts" /id="D624" /incds=0 /nref=21 /ntot=196 /MaxReadThrough="1.58906" /MaxDrop="5.17491" /score="28.2861081" /energy="-15.2" /TU="NA" /idTUdmin="U920" /TUdmin="-8" /isTUend="TRUE" promotor_-35 1225500..1225503 /Source="Nicolas_upshift_promotors" /id="U922" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.651348651348651" /psig="0.97002997002997" /xcortree=3166 /SigmaFactorBS="caatccttcaagagatttctcttgaaggatttttttgcgtct tcATAGaaagtgagaatgatAACATTTACAATTAGAGGAAaaagcggaggcgaaatac g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 1225516 /Source="Nicolas_upshifts" /id="U922" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.651348651348651" /psig="0.97002997002997" /xcortree=3166 /SigmaFactorBS="caatccttcaagagatttctcttgaaggatttttttgcgtct tcATAGaaagtgagaatgatAACATTTACAATTAGAGGAAaaagcggaggcgaaatac g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 1225518..1225537 /Source="Nicolas_upshift_promotors" /id="U922" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.651348651348651" /psig="0.97002997002997" /xcortree=3166 /SigmaFactorBS="caatccttcaagagatttctcttgaaggatttttttgcgtct tcATAGaaagtgagaatgatAACATTTACAATTAGAGGAAaaagcggaggcgaaatac g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" CDS 1225557..1226774 /gene="yjbB" /locus_tag="BSU_11480" /old_locus_tag="BSU11480" /function="16.1: Circulate" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 14563878, 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative exporter" /protein_id="NP_389030.2" /db_xref="EnsemblGenomes-Gn:BSU11480" /db_xref="EnsemblGenomes-Tr:CAB13005" /db_xref="GOA:O31600" /db_xref="InterPro:IPR011701" /db_xref="InterPro:IPR020846" /db_xref="InterPro:IPR036259" /db_xref="SubtiList:BG13131" /db_xref="UniProtKB/Swiss-Prot:O31600" /translation="MQFLHNKNVFALLLSQSFQSLAGVLVTIVLMVRIYQMTDSVFLA GLILSFMSFASIAASFCVSPVLRILGFKKVLAGANLLRAVFIILMAYSVTHHGQAFFW ITLLFVFCFSFAGAFFQPARFALLPIIVPKKQYVKANGVISLSNQLFLTAGWGLGGLL TYAVPFELVVGAAICLFVLSGASISVLHVNEEEAAGTAETASVRSIWKDLMIIPIVRD ITVMDMLEALAGSVWSSAILLAFTAAVLHETEVWWGMFNASYFIGAIVGSVIAIRFSS FFERNMGYAIMFSSLVMSALTLLFSFSPVPFLCALACAAMGPFYQVRDICQETMLQEV IPEQKRIGIMAAKNAILTPWSGVTYSIMGLVADAAGAKIAFIAAAALYIMTFLIALAQ PRLVHYRRENRVQ*" gene 1225557..1226774 /gene="yjbB" /locus_tag="BSU_11480" /old_locus_tag="BSU11480" promotor_-35 1226827..1226836 /Source="Nicolas_upshift_promotors" /id="U923" /multdbtbs="SigW,SigX" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=114 /SigmaFactorBS="cagctggctccgttttgctgaaaaaaaaaTGAAACCATGgcg gaagttcgcACGTCTTTATAGATGTaaggctgtttaaacaagaagaaatggggtatat c" /listShort="S408, yjbC, S409, spxA, S410" /listLong="S411, mecA" /label="promotor_-35" promotor_-10 1226849..1226864 /Source="Nicolas_upshift_promotors" /id="U923" /multdbtbs="SigW,SigX" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=114 /SigmaFactorBS="cagctggctccgttttgctgaaaaaaaaaTGAAACCATGgcg gaagttcgcACGTCTTTATAGATGTaaggctgtttaaacaagaagaaatggggtatat c" /listShort="S408, yjbC, S409, spxA, S410" /listLong="S411, mecA" /label="promotor_-10" S_feature 1226858..1226937 /Source="Nicolas_S_feature" /locus_tag="new_1226858_1226937" /HighExp="Etha, B60, M9-stat, T0.30H, Salt, T3.0H, T1.0H, T4.0H, T2.30H, T3.30H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigWXY" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S408" upshifts 1226858 /Source="Nicolas_upshifts" /id="U923" /multdbtbs="SigW,SigX" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=114 /SigmaFactorBS="cagctggctccgttttgctgaaaaaaaaaTGAAACCATGgcg gaagttcgcACGTCTTTATAGATGTaaggctgtttaaacaagaagaaatggggtatat c" /listShort="S408, yjbC, S409, spxA, S410" /listLong="S411, mecA" CDS 1226938..1227516 /gene="yjbC" /locus_tag="BSU_11490" /old_locus_tag="BSU11490" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 17158660, 17158663, 21815947; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative thiol oxidation management factor; putative acetyltransferase" /protein_id="NP_389031.2" /db_xref="EnsemblGenomes-Gn:BSU11490" /db_xref="EnsemblGenomes-Tr:CAB13006" /db_xref="GOA:O31601" /db_xref="InterPro:IPR000182" /db_xref="InterPro:IPR016181" /db_xref="SubtiList:BG13132" /db_xref="UniProtKB/Swiss-Prot:O31601" /translation="MNWYEKLSEYFPIEEMKSKAHMEALLKERSDIYHKDEGKHHILM FAEFDSFIFVDYLYVSKDARGQGLGGKLIAKLKKKNKPILLEVEPVDEDDTDTEKRLR FYQREHFKHAQSIGYRRRSLATNEVNKMEILYWSPKTESEEEILEAMKQTYENIHTYK DEKWYGESYEKTDEVLEIIDEEKQKNIFDQLS*" gene 1226938..1227516 /gene="yjbC" /locus_tag="BSU_11490" /old_locus_tag="BSU11490" S_feature 1227517..1227631 /Source="Nicolas_S_feature" /locus_tag="new_1227517_1227631" /HighExp="B60, Etha, Salt, T0.30H, M9-stat, LoTm, Gly, T1.0H, B36, Heat" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigWXY" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S409" promotor_-10 complement(1227568..1227587) /Source="Nicolas_upshift_promotors" /id="U924" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.507492507492508" /psig="0.622377622377622" /xcortree=51 /SigmaFactorBS="aaaaaggaatctttacaggtattaTACTATAAaaaagtaagt gtgAACAGTATCCTAAGAAAAAAatgtgtcaatccagcaaatttttaatgttcatgat a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1227572) /Source="Nicolas_upshifts" /id="U924" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.507492507492508" /psig="0.622377622377622" /xcortree=51 /SigmaFactorBS="aaaaaggaatctttacaggtattaTACTATAAaaaagtaagt gtgAACAGTATCCTAAGAAAAAAatgtgtcaatccagcaaatttttaatgttcatgat a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(1227601..1227608) /Source="Nicolas_upshift_promotors" /id="U924" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.507492507492508" /psig="0.622377622377622" /xcortree=51 /SigmaFactorBS="aaaaaggaatctttacaggtattaTACTATAAaaaagtaagt gtgAACAGTATCCTAAGAAAAAAatgtgtcaatccagcaaatttttaatgttcatgat a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" misc_feature 1227634..1227647 /Source="Nicolas_upshift_promotors" /id="U925" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.815184815184815" /psig="0.973026973026973" /xcortree=1536 /SigmaFactorBS="cttaggatactgttcacacttacttttttatagtataatacc tgtaaagattccttttttAGAGTAATTTCAATttaagaataaaatagatgttcatcct a" /listShort="spxA" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 1227634 /Source="Nicolas_upshifts" /id="U925" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.815184815184815" /psig="0.973026973026973" /xcortree=1536 /SigmaFactorBS="cttaggatactgttcacacttacttttttatagtataatacc tgtaaagattccttttttAGAGTAATTTCAATttaagaataaaatagatgttcatcct a" /listShort="spxA" /GFF_Attribute="listLong" CDS 1227697..1228092 /gene="spxA" /locus_tag="BSU_11500" /old_locus_tag="BSU11500" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:12642660, 14597697, 15659166, 16249335, 16740936, 18662407, 22307755, 23894131, 28484046, 22720735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12642660, 14597697, 15659166, 16249335, 16740936, 18662407, 22307755, 23894131, 28484046, 22720735; Product type r: regulator" /codon_start=1 /transl_table=11 /product="redox-sensitive regulator" /protein_id="NP_389032.1" /db_xref="EnsemblGenomes-Gn:BSU11500" /db_xref="EnsemblGenomes-Tr:CAB13007" /db_xref="GOA:O31602" /db_xref="InterPro:IPR006504" /db_xref="InterPro:IPR006660" /db_xref="InterPro:IPR023731" /db_xref="InterPro:IPR036249" /db_xref="PDB:1Z3E" /db_xref="PDB:3GFK" /db_xref="PDB:3IHQ" /db_xref="SubtiList:BG13133" /db_xref="UniProtKB/Swiss-Prot:O31602" /translation="MVTLYTSPSCTSCRKARAWLEEHEIPFVERNIFSEPLSIDEIKQ ILRMTEDGTDEIISTRSKVFQKLNVNVESMPLQDLYRLINEHPGLLRRPIIIDEKRLQ VGYNEDEIRRFLPRKVRSFQLREAQRLAN*" gene 1227697..1228092 /gene="spxA" /locus_tag="BSU_11500" /old_locus_tag="BSU11500" promotor_no_box complement(1227928..1228028) /Source="Nicolas_upshift_promotors" /id="U926" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.96103896103896" /psig="0.000999000999001" /xcortree=57 /SigmaFactorBS="ctgatttcgtcttcgttatatccgacctgcaaacgtttttcg tcaatgatgatcggacggcgaagcaaacctggatgctcgttgatcaagcggtacaaat c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_no_box" upshifts complement(1227968) /Source="Nicolas_upshifts" /id="U926" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.96103896103896" /psig="0.000999000999001" /xcortree=57 /SigmaFactorBS="ctgatttcgtcttcgttatatccgacctgcaaacgtttttcg tcaatgatgatcggacggcgaagcaaacctggatgctcgttgatcaagcggtacaaat c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" downshifts 1228090 /Source="Nicolas_upshifts" /id="D625" /incds=0 /nref=263 /ntot=269 /MaxReadThrough="4.34531" /MaxDrop="8.0579" /score="7.42972561" /energy="-8.8" /TU="U923" /idTUdmin="U925" /TUdmin=0 /isTUend="TRUE" S_feature 1228135..1228924 /Source="Nicolas_S_feature" /locus_tag="new_1228135_1228924" /HighExp="B60, B36, Etha, M9-stat, Salt, H2O2, Paraq, Cold, G180, G135" /AntisenseName="yjbE" /AntisenseCor="-0.18634010398760401" /AntisenseRegPval="-2.7" /CDS_PredictionProba="NA" /TUshortSig="SigWXY" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S410" CDS complement(1228135..1228791) /gene="yjbE" /locus_tag="BSU_11510" /old_locus_tag="BSU11510" /function="16.8: Protect" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative membrane protein of unknown function" /protein_id="NP_389033.1" /db_xref="EnsemblGenomes-Gn:BSU11510" /db_xref="EnsemblGenomes-Tr:CAB13008" /db_xref="GOA:O31603" /db_xref="InterPro:IPR005496" /db_xref="InterPro:IPR022301" /db_xref="SubtiList:BG13134" /db_xref="UniProtKB/Swiss-Prot:O31603" /translation="MEHDYLISLLVIVGIDLILGGDNAVVIAMASRHLPDKQRQQAII LGTFIAVAMRIGLTSAAVYLLNIPFLQCAGGIFLLYLGYQLLIEKKDTKHIKSSTSLW RAIRTIVLADLFMSLDNVIAVAGASHGEFSLVVIGLCVSVPVIIWGSKLIHIALEKIP LLIYAGSGLLAYTGGEMIVRDKKLSLFMAQHGTVETLLPILTVAFVILASIYYQQVEK *" gene complement(1228135..1228791) /gene="yjbE" /locus_tag="BSU_11510" /old_locus_tag="BSU11510" promotor_-10 complement(1228821..1228839) /Source="Nicolas_upshift_promotors" /id="U927" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=987 /SigmaFactorBS="cacctttgcctaaaaaacggcagatcaggcggctgatATCAT AaaatatgacctgtcTCATATAGTAGTAGTACAAgcgaaggactgaaagcgaggtgcc g" /listShort="yjbE" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1228836) /Source="Nicolas_upshifts" /id="U927" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=987 /SigmaFactorBS="cacctttgcctaaaaaacggcagatcaggcggctgatATCAT AaaatatgacctgtcTCATATAGTAGTAGTACAAgcgaaggactgaaagcgaggtgcc g" /listShort="yjbE" /GFF_Attribute="listLong" promotor_-35 complement(1228854..1228859) /Source="Nicolas_upshift_promotors" /id="U927" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=987 /SigmaFactorBS="cacctttgcctaaaaaacggcagatcaggcggctgatATCAT AaaatatgacctgtcTCATATAGTAGTAGTACAAgcgaaggactgaaagcgaggtgcc g" /listShort="yjbE" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1228897..1228904 /Source="Nicolas_upshift_promotors" /id="U928" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.845154845154845" /psig="0.998001998001998" /xcortree=622 /SigmaFactorBS="cgcctgatctgccgttttttaggcaaaggtgCATTTTTAttt cttttgtgacTGTTTTATCATAAAATAGAAatacaaaggaattcacactggccttggt t" /listShort="S411, mecA, S412, S413, coiA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1228918..1228937 /Source="Nicolas_upshift_promotors" /id="U928" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.845154845154845" /psig="0.998001998001998" /xcortree=622 /SigmaFactorBS="cgcctgatctgccgttttttaggcaaaggtgCATTTTTAttt cttttgtgacTGTTTTATCATAAAATAGAAatacaaaggaattcacactggccttggt t" /listShort="S411, mecA, S412, S413, coiA" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 1228926..1229067 /Source="Nicolas_S_feature" /locus_tag="new_1228926_1229067" /HighExp="B60, Diami, Etha, dia5, LPhT, M9-stat, T5.0H, T3.0H, dia15, T0.30H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.998" /TUlongSig="SigWXY" /TUlongPSig=1 /label="S411" upshifts 1228926 /Source="Nicolas_upshifts" /id="U928" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.845154845154845" /psig="0.998001998001998" /xcortree=622 /SigmaFactorBS="cgcctgatctgccgttttttaggcaaaggtgCATTTTTAttt cttttgtgacTGTTTTATCATAAAATAGAAatacaaaggaattcacactggccttggt t" /listShort="S411, mecA, S412, S413, coiA" /GFF_Attribute="listLong" CDS 1228961..1229101 /locus_tag="BSU_11515" /old_locus_tag="BSU11515" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="YP_009513949.1" /translation="MVKVKMWTEWVKCSKVQLIGSLDVPSTSYIEGKVGKWKLKELTS IQ*" gene 1228961..1229101 /locus_tag="BSU_11515" /old_locus_tag="BSU11515" CDS 1229068..1229724 /gene="mecA" /locus_tag="BSU_11520" /old_locus_tag="BSU11520" /function="16.3: Control" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:10361283, 10447896, 16525504, 19801546, 21435029, 23595989" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10361283, 10447896, 16525504, 19801546, 21435029, 23595989; Product type f : factor" /codon_start=1 /transl_table=11 /product="adaptor protein controlling oligomerization of the AAA+ protein ClpC" /protein_id="NP_389034.1" /db_xref="EnsemblGenomes-Gn:BSU11520" /db_xref="EnsemblGenomes-Tr:CAB13009" /db_xref="GOA:P37958" /db_xref="InterPro:IPR008681" /db_xref="PDB:2Y1R" /db_xref="PDB:3J3R" /db_xref="PDB:3J3S" /db_xref="PDB:3J3T" /db_xref="PDB:3J3U" /db_xref="PDB:3JTP" /db_xref="PDB:3PXG" /db_xref="PDB:3PXI" /db_xref="SubtiList:BG10680" /db_xref="UniProtKB/Swiss-Prot:P37958" /translation="MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEV MDEVHEEEEFAVEGPLWIQVQALDKGLEIIVTKAQLSKDGQKLELPIPEDKKQEPASE DLDALLDDFQKEEQAVNQEEKEQKLQFVLRFGDFEDVISLSKLNVNGSKTTLYSFENR YYLYVDFCNMTDEEVENQLSILLEYATESSISIHRLEEYGKLIISEHALETIKKHFAS *" gene 1229068..1229724 /gene="mecA" /locus_tag="BSU_11520" /old_locus_tag="BSU11520" downshifts 1229714 /Source="Nicolas_upshifts" /id="D626" /incds=0 /nref=120 /ntot=308 /MaxReadThrough="5.41786" /MaxDrop="7.67172" /score="32.2431225" /energy="-11.8" /TU="U928" /idTUdmin="U928" /TUdmin="-774" /isTUend="FALSE" CDS complement(1229719..1229841) /locus_tag="BSU_11525" /old_locus_tag="BSU11525" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="YP_009513950.1" /translation="MINSCSLYFLLVYMFLIFHISKMAFSCIKKTDFRKEIGLL*" gene complement(1229719..1229841) /locus_tag="BSU_11525" /old_locus_tag="BSU11525" S_feature 1229759..1229848 /Source="Nicolas_S_feature" /locus_tag="new_1229759_1229848" /HighExp="Etha, M9-stat, B60, dia15, T0.30H, Diami, C30, H2O2, dia5, S8" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.998" /TUlongSig="NA" /TUlongPSig="NA" /label="S412" promotor_-35 1229827..1229835 /Source="Nicolas_upshift_promotors" /id="U929" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.876123876123876" /psig="0.876123876123876" /xcortree=2965 /SigmaFactorBS="aaatcaaaaacatatagacaagcagaaaatacagcgaACAGG AGTTgatcatctttTCCAGAAAGTATACTTCATctggaaaggagagatgacaattgtt t" /listShort="S413, coiA, pepF" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1229846..1229864 /Source="Nicolas_upshift_promotors" /id="U929" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.876123876123876" /psig="0.876123876123876" /xcortree=2965 /SigmaFactorBS="aaatcaaaaacatatagacaagcagaaaatacagcgaACAGG AGTTgatcatctttTCCAGAAAGTATACTTCATctggaaaggagagatgacaattgtt t" /listShort="S413, coiA, pepF" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 1229850..1229914 /Source="Nicolas_S_feature" /locus_tag="new_1229850_1229914" /HighExp="Etha, G/S, GM 150, T-4.40H, S2, T-2.40H, Pyr, C90, M9-tran, T-3.40H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigH, SigA" /TUshortPSig="0.876, 0.998" /TUlongSig="NA" /TUlongPSig="NA" /label="S413" upshifts 1229850 /Source="Nicolas_upshifts" /id="U929" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.876123876123876" /psig="0.876123876123876" /xcortree=2965 /SigmaFactorBS="aaatcaaaaacatatagacaagcagaaaatacagcgaACAGG AGTTgatcatctttTCCAGAAAGTATACTTCATctggaaaggagagatgacaattgtt t" /listShort="S413, coiA, pepF" /GFF_Attribute="listLong" CDS 1229915..1231036 /gene="coiA" /locus_tag="BSU_11530" /old_locus_tag="BSU11530" /function="16.1: Circulate" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:10438773, 17630974, 23046409, 26880300" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10438773, 17630974, 23046409, 26880300; Product type s: structure" /codon_start=1 /transl_table=11 /product="protein involved in establishment of DNA transport in competence" /protein_id="NP_389035.1" /db_xref="EnsemblGenomes-Gn:BSU11530" /db_xref="EnsemblGenomes-Tr:CAB13010" /db_xref="GOA:O31604" /db_xref="InterPro:IPR010330" /db_xref="InterPro:IPR021176" /db_xref="SubtiList:BG13135" /db_xref="UniProtKB/Swiss-Prot:O31604" /translation="MFHLLGAQQNQKLKRRRFFCPVCGGELAVKLGLQKAPHFAHKQN KSCAIDIEPESAYHLEGKRQLYVWLKTQRASPILEPYIRTINQRPDVMARIKEHMLAV EYQCATIAPDVFQKRTEGFKQEGIIPQWIMGYSRLKRTASSFYQLSTFHWQFINASPY RELICYCPERRSFLRLSHIIPFYTNHSYSSVQTIPIHRAGAGDLFFTEPKPSIQYSGW TKAIHRFRHKPHRFNSKETNRLRLLFYEKRQTPFSFLPTEVFVPVRKGAVFKSPVFVW QGFLYLFMTDLGGKRAPIRFSAVLQQCKLHIHNKNIALRSECSEECLSEAVKQYIDFL CKKGFLRETQKEVYVLNQPAGGIHSMQDLIERDRSCFIE*" gene 1229915..1231036 /gene="coiA" /locus_tag="BSU_11530" /old_locus_tag="BSU11530" promotor_-35 1230690..1230696 /Source="Nicolas_upshift_promotors" /id="U930" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=156 /SigmaFactorBS="atgagaaacgacagacgcctttttcttttctgccgactgaag TGTTTGTtcctgttagaaaagGGGCAGTTTTTAAGAGTCCggtttttgtgtggcaggg g" /listShort="pepF" /listLong="S414, S415" /label="promotor_-35" upshifts 1230708 /Source="Nicolas_upshifts" /id="U930" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=156 /SigmaFactorBS="atgagaaacgacagacgcctttttcttttctgccgactgaag TGTTTGTtcctgttagaaaagGGGCAGTTTTTAAGAGTCCggtttttgtgtggcaggg g" /listShort="pepF" /listLong="S414, S415" promotor_-10 1230711..1230729 /Source="Nicolas_upshift_promotors" /id="U930" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=156 /SigmaFactorBS="atgagaaacgacagacgcctttttcttttctgccgactgaag TGTTTGTtcctgttagaaaagGGGCAGTTTTTAAGAGTCCggtttttgtgtggcaggg g" /listShort="pepF" /listLong="S414, S415" /label="promotor_-10" promotor_-35 1230922..1230930 /Source="Nicolas_upshift_promotors" /id="U931" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=546 /SigmaFactorBS="agcggttaaacagtatattgattttttgtgcaaGAAGGGATT tttaagggagaCTCAGAAAGAAGTATATGTgctgaatcagcctgcaggaggcatacac t" /listShort="pepF" /listLong="S414, S415" /label="promotor_-35" promotor_-10 1230942..1230960 /Source="Nicolas_upshift_promotors" /id="U931" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=546 /SigmaFactorBS="agcggttaaacagtatattgattttttgtgcaaGAAGGGATT tttaagggagaCTCAGAAAGAAGTATATGTgctgaatcagcctgcaggaggcatacac t" /listShort="pepF" /listLong="S414, S415" /label="promotor_-10" upshifts 1230949 /Source="Nicolas_upshifts" /id="U931" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=546 /SigmaFactorBS="agcggttaaacagtatattgattttttgtgcaaGAAGGGATT tttaagggagaCTCAGAAAGAAGTATATGTgctgaatcagcctgcaggaggcatacac t" /listShort="pepF" /listLong="S414, S415" promotor_-35 1231030..1231036 /Source="Nicolas_upshift_promotors" /id="U932" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=911 /SigmaFactorBS="tctcatagaaagagaccgcagctgttttatAGAATGAgtttg tcttatttgGCTCACCCTAAGacaaaggtggtgggcaggctgtgaaaggcacaaaagg a" /listShort="pepF" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1231051..1231062 /Source="Nicolas_upshift_promotors" /id="U932" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=911 /SigmaFactorBS="tctcatagaaagagaccgcagctgttttatAGAATGAgtttg tcttatttgGCTCACCCTAAGacaaaggtggtgggcaggctgtgaaaggcacaaaagg a" /listShort="pepF" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1231060 /Source="Nicolas_upshifts" /id="U932" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=911 /SigmaFactorBS="tctcatagaaagagaccgcagctgttttatAGAATGAgtttg tcttatttgGCTCACCCTAAGacaaaggtggtgggcaggctgtgaaaggcacaaaagg a" /listShort="pepF" /GFF_Attribute="listLong" CDS 1231083..1233095 /gene="pepF" /locus_tag="BSU_11540" /old_locus_tag="BSU11540" /function="16.11: Scavenge (Catabolism)" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:11741842" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11741842; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="oligoendopeptidase F" /protein_id="NP_389036.2" /db_xref="EnsemblGenomes-Gn:BSU11540" /db_xref="EnsemblGenomes-Tr:CAB13011" /db_xref="GOA:O31605" /db_xref="InterPro:IPR001567" /db_xref="InterPro:IPR004438" /db_xref="InterPro:IPR013647" /db_xref="SubtiList:BG13136" /db_xref="UniProtKB/Swiss-Prot:O31605" /translation="MKGTKGKVFRVFTAFLAFVLFITAYDLTKGSEKPEDIHNTSLLR NSCFFNWLESKKTRGITMAEEKKANQLPDRSEVKAEDTWRLEDIFPSDEAWNKEFQAV KELIPNLSKYKGKLADSADHLYEALTYQDKVMERLGRLYTYAHMRSDQDTGNSFYQGL NDKAGNLYTQAASATAYLVPEILSIEEDKLQQFILEKEELKLYSHAIEEITKERPHVL SEKEEALLAEASEVLGSSSNTFSVLNNADITFPSIKDEDGNEKQITHGNFINFLESEN REVRKNAFDAVYKTYGQYKNTMATTLSGTVKKDNFYARVKKYKSAREAALSNNSIPEE VYDNLVKTINKHLPLLHRYIALRKKVLELDEVHIYDLYTPLVKDAGMKVTYEEAKDYM LKGLAPLGEEYASILKEGLENRWVDVYENKGKRNGAYSSGAYGTNPYILMNWHNNVNN LFTLVHEFGHSVHSYYTRKHQPYPYGNYSIFVAEVASTTNEALLGEYLLNNLEDEKQR LYILNHMLEGFRGTVFRQTMFAEFEHLIHTKAQEGEPLTPELLTNVYYDLNKKYFGDG MVIDKEIGLEWSRIPHFYYNYYVYQYATGYSAAQALSSQILKEGKPAVDRYIDFLKAG SSQYPIDVLKKAGVDMTSPEPIEAACKMFEEKLDEMEELLMKVKQS*" gene 1231083..1233095 /gene="pepF" /locus_tag="BSU_11540" /old_locus_tag="BSU11540" promotor_-35 1231158..1231165 /Source="Nicolas_upshift_promotors" /id="U933" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.802197802197802" /psig="0.926073926073926" /xcortree=3181 /SigmaFactorBS="cattcgttctcttcattactgcatatGATTTGACaaaaggca gtgaaaAACCGGAAGATATTCACAACacaagtttattgagaaacagctgttttttcaa t" /listShort="S414" /listLong="S415" /label="promotor_-35" promotor_-10 1231180..1231199 /Source="Nicolas_upshift_promotors" /id="U933" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.802197802197802" /psig="0.926073926073926" /xcortree=3181 /SigmaFactorBS="cattcgttctcttcattactgcatatGATTTGACaaaaggca gtgaaaAACCGGAAGATATTCACAACacaagtttattgagaaacagctgttttttcaa t" /listShort="S414" /listLong="S415" /label="promotor_-10" upshifts 1231192 /Source="Nicolas_upshifts" /id="U933" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.802197802197802" /psig="0.926073926073926" /xcortree=3181 /SigmaFactorBS="cattcgttctcttcattactgcatatGATTTGACaaaaggca gtgaaaAACCGGAAGATATTCACAACacaagtttattgagaaacagctgttttttcaa t" /listShort="S414" /listLong="S415" downshifts 1233042 /Source="Nicolas_upshifts" /id="D627" /incds=0 /nref=98 /ntot=339 /MaxReadThrough="4.70576" /MaxDrop="5.74441" /score="19.0969124" /energy="-15.2" /TU="U933" /idTUdmin="U931" /TUdmin=2 /isTUend="TRUE" S_feature 1233096..1233397 /Source="Nicolas_S_feature" /locus_tag="new_1233096_1233397" /HighExp="Etha, dia15, Diami, B60, M9-stat, S8, M0t90, dia5, B36, T0.30H" /AntisenseName="yizD" /AntisenseCor="-1.29003203536192E-2" /AntisenseRegPval="-0.1" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.926" /TUlongSig="SigH, SigB" /TUlongPSig="0.999, 0.999" /label="S414" CDS complement(1233133..1233300) /gene="yizD" /locus_tag="BSU_11549" /old_locus_tag="BSU11549" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="YP_003097703.1" /db_xref="EnsemblGenomes-Gn:BSU11549" /db_xref="EnsemblGenomes-Tr:CAX52593" /db_xref="GOA:C0H3Y6" /db_xref="UniProtKB/Swiss-Prot:C0H3Y6" /translation="MMSTLISIVCIAVFFCLNILGMMHMLPLYITSPLLFLSILFTLY RLNHRKTFKGF*" gene complement(1233133..1233300) /gene="yizD" /locus_tag="BSU_11549" /old_locus_tag="BSU11549" downshifts complement(1233146) /Source="Nicolas_upshifts" /id="D628" /incds=0 /nref=8 /ntot=61 /MaxReadThrough="1.527" /MaxDrop="5.54041" /score="-4.56163992" /energy="-15.2" /TU="NA" /idTUdmin="U934" /TUdmin="-8" /isTUend="TRUE" promotor_-10 complement(1233320..1233338) /Source="Nicolas_upshift_promotors" /id="U934" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1166 /SigmaFactorBS="acaacctctatgcttaatgttcatatttttgtcacaaAACAT AacgaagtgcattcacTCATATCCTTATAAGGAAAaaggacgaggaggaccgccatga t" /listShort="yizD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1233336) /Source="Nicolas_upshifts" /id="U934" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1166 /SigmaFactorBS="acaacctctatgcttaatgttcatatttttgtcacaaAACAT AacgaagtgcattcacTCATATCCTTATAAGGAAAaaggacgaggaggaccgccatga t" /listShort="yizD" /GFF_Attribute="listLong" promotor_-35 complement(1233354..1233359) /Source="Nicolas_upshift_promotors" /id="U934" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1166 /SigmaFactorBS="acaacctctatgcttaatgttcatatttttgtcacaaAACAT AacgaagtgcattcacTCATATCCTTATAAGGAAAaaggacgaggaggaccgccatga t" /listShort="yizD" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1233390..1233397 /Source="Nicolas_upshift_promotors" /id="U935" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.583416583416583" /psig="0.883116883116883" /xcortree=90 /SigmaFactorBS="gtgaatgcacttcgttatgttttgtgacaaaaatatgaacat taagcatagAGGTTGTCaaaagtcgacatctTTTGTTATCATAAGGATGTGaaattga t" /listShort="S415" /GFF_Attribute="listLong" /label="promotor_-35" S_feature 1233399..1233524 /Source="Nicolas_S_feature" /locus_tag="new_1233399_1233524" /HighExp="B36, T-1.10H, nit, T-0.40H, M9-tran, LoTm, Pyr, Etha, Salt, T0.30H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.883" /TUlongSig="SigA, SigH, SigB" /TUlongPSig="0.926, 0.999, 0.999" /label="S415" upshifts 1233399 /Source="Nicolas_upshifts" /id="U935" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.583416583416583" /psig="0.883116883116883" /xcortree=90 /SigmaFactorBS="gtgaatgcacttcgttatgttttgtgacaaaaatatgaacat taagcatagAGGTTGTCaaaagtcgacatctTTTGTTATCATAAGGATGTGaaattga t" /listShort="S415" /GFF_Attribute="listLong" misc_RNA 1233405..1233543 /gene="roxS" /locus_tag="BSU_misc_RNA_67" /product="small regulatory RNA (NO regulated)" /experiment="publication(s) with functional evidences, PMID:19682248, 19786493, 20511587, 20525796, 25643072, 28436820" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 19682248, 19786493, 20511587, 20525796, 25643072, 28436820; Product type n : RNA" gene 1233405..1233543 /gene="roxS" /locus_tag="BSU_misc_RNA_67" promotor_-10 1233412..1233431 /Source="Nicolas_upshift_promotors" /id="U935" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.583416583416583" /psig="0.883116883116883" /xcortree=90 /SigmaFactorBS="gtgaatgcacttcgttatgttttgtgacaaaaatatgaacat taagcatagAGGTTGTCaaaagtcgacatctTTTGTTATCATAAGGATGTGaaattga t" /listShort="S415" /GFF_Attribute="listLong" /label="promotor_-10" downshifts 1233481 /Source="Nicolas_upshifts" /id="D629" /incds=0 /nref=96 /ntot=135 /MaxReadThrough="3.50613" /MaxDrop="9.07209" /score="5.30186633" /energy="-11.6" /TU="U935" /idTUdmin="U933" /TUdmin=89 /isTUend="FALSE" CDS complement(1233614..1234513) /gene="spxH" /locus_tag="BSU_11550" /old_locus_tag="BSU11550" /function="16.3: Control" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:17293416, 17908206, 21378193, 22194450, 24942655, 25353645, 27191337, 22720735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 17293416, 17908206, 21378193, 22194450, 24942655, 25353645, 27191337, 22720735; Product type f: factor" /codon_start=1 /transl_table=11 /product="thiol management effector of SpxA degradation" /protein_id="NP_389037.2" /db_xref="EnsemblGenomes-Gn:BSU11550" /db_xref="EnsemblGenomes-Tr:CAB13012" /db_xref="GOA:O31606" /db_xref="InterPro:IPR036249" /db_xref="SubtiList:BG13137" /db_xref="UniProtKB/Swiss-Prot:O31606" /translation="MTNYQHELYFAHCHGHPKKPLEIYMFVDPLCPECWSLEPVIKKL KIRYGRFFTLRIIASASLTALNKKRKKHLLAEAWEKIASRSGMSCDGNVWFEQDQPLS SPYMAALAFKAAELQGRKAGMQFLRNMQESLFVSKKNITDENVLLEIAENTSLDLEEF KKDLHSQSAVKALQCDMKIAAEMDVSVNPTLTFFNTQHEDEGLKVPGSYSYDVYEEIL FEMLGDEPKPSETPPLECFIEYFRFVASKEIALVYDLSLEEVEKEMKKLAFAKKVAKV EAKHGMFWKSLSTYSDEYQSCEK*" gene complement(1233614..1234513) /gene="spxH" /locus_tag="BSU_11550" /old_locus_tag="BSU11550" downshifts complement(1233645) /Source="Nicolas_upshifts" /id="D630" /incds=0 /nref=185 /ntot=251 /MaxReadThrough="3.70729" /MaxDrop="5.65601" /score="17.9327625" /energy="-13.3" /TU="U937" /idTUdmin="U937" /TUdmin="-89" /isTUend="FALSE" promotor_-35 1233849..1233854 /Source="Nicolas_upshift_promotors" /id="U936" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=1111 /SigmaFactorBS="ataaaacattctaaaggcggtgtttccgacggcttcggctcg tcgccaAGCATCtcaaataaaatttctTCATATACATCATATGAGTagctgccaggaa c" /listShort="S416" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 1233861 /Source="Nicolas_upshifts" /id="U936" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=1111 /SigmaFactorBS="ataaaacattctaaaggcggtgtttccgacggcttcggctcg tcgccaAGCATCtcaaataaaatttctTCATATACATCATATGAGTagctgccaggaa c" /listShort="S416" /GFF_Attribute="listLong" promotor_-10 1233870..1233888 /Source="Nicolas_upshift_promotors" /id="U936" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=1111 /SigmaFactorBS="ataaaacattctaaaggcggtgtttccgacggcttcggctcg tcgccaAGCATCtcaaataaaatttctTCATATACATCATATGAGTagctgccaggaa c" /listShort="S416" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 1233877..1235778 /Source="Nicolas_S_feature" /locus_tag="new_1233877_1235778" /HighExp="S6, S4, S5, S8, S3, S7, BT, B36, C30, T5.0H" /AntisenseName="yjbH" /AntisenseCor="-0.61019541931037402" /AntisenseRegPval="-28.1" /CDS_PredictionProba="NA" /TUshortSig="SigEF" /TUshortPSig="0.998" /TUlongSig="NA" /TUlongPSig="NA" /label="S416" CDS complement(1234510..1234908) /gene="yjbI" /locus_tag="BSU_11560" /old_locus_tag="BSU11560" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15866723, 17293416; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative thiol management oxidoreductase component" /protein_id="NP_389038.1" /db_xref="EnsemblGenomes-Gn:BSU11560" /db_xref="EnsemblGenomes-Tr:CAB13013" /db_xref="GOA:O31607" /db_xref="InterPro:IPR001486" /db_xref="InterPro:IPR009050" /db_xref="InterPro:IPR019795" /db_xref="PDB:1UX8" /db_xref="SubtiList:BG13138" /db_xref="UniProtKB/Swiss-Prot:O31607" /translation="MGQSFNAPYEAIGEELLSQLVDTFYERVASHPLLKPIFPSDLTE TARKQKQFLTQYLGGPPLYTEEHGHPMLRARHLPFPITNERADAWLSCMKDAMDHVGL EGEIREFLFGRLELTARHMVNQTEAEDRSS*" gene complement(1234510..1234908) /gene="yjbI" /locus_tag="BSU_11560" /old_locus_tag="BSU11560" S_feature complement(1234909..1235088) /Source="Nicolas_S_feature" /locus_tag="new_1234909_1235088_c" /HighExp="Diami, dia5, dia15, Etha, H2O2, C90, LoTm, Heat, Salt, M0t90" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="SigD, SigA" /TUlongPSig="1, 0.999" /label="S417" promotor_-10 complement(1235080..1235099) /Source="Nicolas_upshift_promotors" /id="U937" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.98101898101898" /psig=1 /xcortree=1912 /SigmaFactorBS="tccctctggtttttttgcgaagtgaaatctTACGCATTcctg atttttaTGTGATATGATATGAAATACaaaccccggctgtcagccgaaatgagtcatc a" /listShort="S417, yjbI, yjbH" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1235088) /Source="Nicolas_upshifts" /id="U937" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.98101898101898" /psig=1 /xcortree=1912 /SigmaFactorBS="tccctctggtttttttgcgaagtgaaatctTACGCATTcctg atttttaTGTGATATGATATGAAATACaaaccccggctgtcagccgaaatgagtcatc a" /listShort="S417, yjbI, yjbH" /GFF_Attribute="listLong" promotor_-35 complement(1235111..1235118) /Source="Nicolas_upshift_promotors" /id="U937" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.98101898101898" /psig=1 /xcortree=1912 /SigmaFactorBS="tccctctggtttttttgcgaagtgaaatctTACGCATTcctg atttttaTGTGATATGATATGAAATACaaaccccggctgtcagccgaaatgagtcatc a" /listShort="S417, yjbI, yjbH" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(1235163..1235708) /gene="cwlQ" /locus_tag="BSU_11570" /old_locus_tag="BSU11570" /EC_number="3.2.1.-" /EC_number="3.2.1.17" /function="16.5: Explore" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:20609359" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 20609359; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="bifunctional muramidase and murein lytic transglycosylase" /protein_id="NP_389039.1" /db_xref="EnsemblGenomes-Gn:BSU11570" /db_xref="EnsemblGenomes-Tr:CAB13014" /db_xref="GOA:O31608" /db_xref="InterPro:IPR000189" /db_xref="InterPro:IPR008258" /db_xref="InterPro:IPR023346" /db_xref="SubtiList:BG13139" /db_xref="UniProtKB/Swiss-Prot:O31608" /translation="MLNSANTTAPSLLSAYGLNSYTSSNSGSVTKAAESTETAVADSA SNKHEANQIRSGDFSIDSAIKKAADKYGVDEKLIRAVIKQESGFNAKAVSGAGAMGLM QLMPSTASSLGVSNPLDPQQNVEGGTKYLKQMLDKYDGNVSMALAAYNAGPGNVDRYG GIPPFQETQNYVKKITSVYYA*" gene complement(1235163..1235708) /gene="cwlQ" /locus_tag="BSU_11570" /old_locus_tag="BSU11570" downshifts complement(1235187) /Source="Nicolas_upshifts" /id="D631" /incds=0 /nref=101 /ntot=222 /MaxReadThrough="4.1014" /MaxDrop="5.00847" /score="6.97790581" /energy="-9.1" /TU="U938,U939" /idTUdmin="U938" /TUdmin="-90" /isTUend="FALSE" S_feature complement(1235709..1235911) /Source="Nicolas_S_feature" /locus_tag="new_1235709_1235911_c" /HighExp="T0.30H, Gly, C90, GM 10, GM 45, M0t90, Lbstat, C30, Lbtran, GM 25" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigD, SigA" /TUshortPSig="1, 0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S418" CDS complement(1235912..1236484) /gene="yjbK" /locus_tag="BSU_11580" /old_locus_tag="BSU11580" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 9642185, 12456267, 16905149, 20509597, 26904951, 27881678; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="putative RNA/thiamine triphosphatase" /protein_id="NP_389040.1" /db_xref="EnsemblGenomes-Gn:BSU11580" /db_xref="EnsemblGenomes-Tr:CAB13015" /db_xref="GOA:O31609" /db_xref="InterPro:IPR009195" /db_xref="InterPro:IPR023577" /db_xref="InterPro:IPR033469" /db_xref="SubtiList:BG13140" /db_xref="UniProtKB/Swiss-Prot:O31609" /translation="MSQEIEIEFKNMLTKQEFKNIASALQLTEKDFTDQKNHYFDTDS FALKQKHAALRIRRKNGKYVLTLKEPADVGLLETHQQLSEVSDLAGFSVPEGPVKDQL HKLQIDTDAIQYFGSLATNRAEKETEKGLIVLDHSRYLNKEDYEIEFEAADWHEGRQA FEKLLQQFSIPQRETKNKILRFYEEKRKSI*" gene complement(1235912..1236484) /gene="yjbK" /locus_tag="BSU_11580" /old_locus_tag="BSU11580" promotor_-10 complement(1236057..1236075) /Source="Nicolas_upshift_promotors" /id="U938" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2803 /SigmaFactorBS="caaaccgtgcggaaaaagaaacagaaaaaggCTTAATAGttt tagaccacaGCCGATATTTAAATAAAGAggactatgaaattgaatttgaggcggcgga t" /listShort="S418, yjbJ" /listLong="S417, yjbI, yjbH" /label="promotor_-10" upshifts complement(1236066) /Source="Nicolas_upshifts" /id="U938" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2803 /SigmaFactorBS="caaaccgtgcggaaaaagaaacagaaaaaggCTTAATAGttt tagaccacaGCCGATATTTAAATAAAGAggactatgaaattgaatttgaggcggcgga t" /listShort="S418, yjbJ" /listLong="S417, yjbI, yjbH" promotor_-35 complement(1236088..1236095) /Source="Nicolas_upshift_promotors" /id="U938" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2803 /SigmaFactorBS="caaaccgtgcggaaaaagaaacagaaaaaggCTTAATAGttt tagaccacaGCCGATATTTAAATAAAGAggactatgaaattgaatttgaggcggcgga t" /listShort="S418, yjbJ" /listLong="S417, yjbI, yjbH" /label="promotor_-35" promotor_-10 complement(1236513..1236532) /Source="Nicolas_upshift_promotors" /id="U939" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.782217782217782" /psig="0.999000999001" /xcortree=2255 /SigmaFactorBS="acaaagtacagattcattttatcatatcgagctcgaTATTGA TAaacctaacatctaaAGAGATAATAGTAAAAATAAgatttacagggcggaaaggaag a" /listShort="yjbK, S418, yjbJ" /listLong="S417, yjbI, yjbH" /label="promotor_-10" upshifts complement(1236530) /Source="Nicolas_upshifts" /id="U939" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.782217782217782" /psig="0.999000999001" /xcortree=2255 /SigmaFactorBS="acaaagtacagattcattttatcatatcgagctcgaTATTGA TAaacctaacatctaaAGAGATAATAGTAAAAATAAgatttacagggcggaaaggaag a" /listShort="yjbK, S418, yjbJ" /listLong="S417, yjbI, yjbH" promotor_-35 1236546..1236549 /Source="Nicolas_upshift_promotors" /id="U940" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.534465534465534" /psig="0.994005994005994" /xcortree=2570 /SigmaFactorBS="ccctgtaaatcttatttttactattatctctttagatgttag gtTTATcaatatcgagctcgaTATGATAAAATGAATCTGTActttgtttaaaaaagga g" /listShort="yjbL, yjbM, ppnKA, yjbO" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 complement(1236547..1236554) /Source="Nicolas_upshift_promotors" /id="U939" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.782217782217782" /psig="0.999000999001" /xcortree=2255 /SigmaFactorBS="acaaagtacagattcattttatcatatcgagctcgaTATTGA TAaacctaacatctaaAGAGATAATAGTAAAAATAAgatttacagggcggaaaggaag a" /listShort="yjbK, S418, yjbJ" /listLong="S417, yjbI, yjbH" /label="promotor_-35" upshifts 1236562 /Source="Nicolas_upshifts" /id="U940" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.534465534465534" /psig="0.994005994005994" /xcortree=2570 /SigmaFactorBS="ccctgtaaatcttatttttactattatctctttagatgttag gtTTATcaatatcgagctcgaTATGATAAAATGAATCTGTActttgtttaaaaaagga g" /listShort="yjbL, yjbM, ppnKA, yjbO" /GFF_Attribute="listLong" promotor_-10 1236565..1236584 /Source="Nicolas_upshift_promotors" /id="U940" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.534465534465534" /psig="0.994005994005994" /xcortree=2570 /SigmaFactorBS="ccctgtaaatcttatttttactattatctctttagatgttag gtTTATcaatatcgagctcgaTATGATAAAATGAATCTGTActttgtttaaaaaagga g" /listShort="yjbL, yjbM, ppnKA, yjbO" /GFF_Attribute="listLong" /label="promotor_-10" CDS 1236609..1236977 /gene="yjbL" /locus_tag="BSU_11590" /old_locus_tag="BSU11590" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 22333191; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_389041.1" /db_xref="EnsemblGenomes-Gn:BSU11590" /db_xref="EnsemblGenomes-Tr:CAB13016" /db_xref="InterPro:IPR020908" /db_xref="SubtiList:BG13141" /db_xref="UniProtKB/Swiss-Prot:O31610" /translation="MQNRIEILNATLSDDQLRLACQTEGNEAERKPSGQMLVDSDHFA FVYILELADSFEYVIIKEHVWPELKQAHAQKIPVVLEAGDQTIELAGLHEELEYLLEN IKDNANYGEEMEEKVKRVFL*" gene 1236609..1236977 /gene="yjbL" /locus_tag="BSU_11590" /old_locus_tag="BSU11590" CDS 1237006..1237641 /gene="relP" /locus_tag="BSU_11600" /old_locus_tag="BSU11600" /EC_number="2.7.6.5" /function="16.1: Circulate" /function="16.14: Store" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:17714452, 18067544, 19447912, 24163341, 25331430, 26825398" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 17714452, 18067544, 19447912, 24163341, 25331430, 26825398; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="(p)ppGpp synthetase" /protein_id="NP_389042.1" /db_xref="EnsemblGenomes-Gn:BSU11600" /db_xref="EnsemblGenomes-Tr:CAB13017" /db_xref="GOA:O31611" /db_xref="InterPro:IPR007685" /db_xref="PDB:5DEC" /db_xref="PDB:5DED" /db_xref="PDB:5F2V" /db_xref="SubtiList:BG13142" /db_xref="UniProtKB/Swiss-Prot:O31611" /translation="MDDKQWERFLVPYRQAVEELKVKLKGIRTLYEYEDDHSPIEFVT GRVKPVASILEKARRKSIPLHEIETMQDIAGLRIMCQFVDDIQIVKEMLFARKDFTVV DQRDYIAEHKESGYRSYHLVVLYPLQTVSGEKHVLVEIQIRTLAMNFWATIEHSLNYK YSGNIPEKVKLRLQRASEAASRLDEEMSEIRGEVQEAQAAFSRKKKGSEQQ*" gene 1237006..1237641 /gene="relP" /locus_tag="BSU_11600" /old_locus_tag="BSU11600" CDS 1237660..1238460 /gene="ppnKA" /locus_tag="BSU_11610" /old_locus_tag="BSU11610" /EC_number="2.7.1.23" /function="16.14: Store" /function="16.7: Manage energy" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:12682299, 12897004, 16233726, 16511117, 18720024, 24048943" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12682299, 12897004, 16233726, 16511117, 18720024, 24048943; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="inorganic polyphosphate/ATP-NAD kinase (quinolate activated)" /protein_id="NP_389043.1" /db_xref="EnsemblGenomes-Gn:BSU11610" /db_xref="EnsemblGenomes-Tr:CAB13018" /db_xref="GOA:O31612" /db_xref="InterPro:IPR002504" /db_xref="InterPro:IPR016064" /db_xref="InterPro:IPR017437" /db_xref="InterPro:IPR017438" /db_xref="SubtiList:BG13143" /db_xref="UniProtKB/Swiss-Prot:O31612" /translation="MKFAVSSKGDQVSDTLKSKIQAYLLDFDMELDENEPEIVISVGG DGTLLYAFHRYSDRLDKTAFVGVHTGHLGFYADWVPHEIEKLVLAIAKTPYHTVEYPL LEVIVTYHENEREERYLALNECTIKSIEGSLVADVEIKGQLFETFRGDGLCLSTPSGS TAYNKALGGAIIHPSIRAIQLAEMASINNRVFRTVGSPLLLPSHHDCMIKPRNEVDFQ VTIDHLTLLHKDVKSIRCQVASEKVRFARFRPFPFWKRVQDSFIGKGE*" gene 1237660..1238460 /gene="ppnKA" /locus_tag="BSU_11610" /old_locus_tag="BSU11610" CDS 1238523..1239374 /gene="yjbO" /locus_tag="BSU_11620" /old_locus_tag="BSU11620" /EC_number="5.4.99.-" /function="16.8: Protect" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2b: Function from indirect experimental evidences (e.g. phenotypes); Product type e: enzyme" /codon_start=1 /transl_table=11 /product="pseudouridylate synthase" /protein_id="NP_389044.1" /db_xref="EnsemblGenomes-Gn:BSU11620" /db_xref="EnsemblGenomes-Tr:CAB13019" /db_xref="GOA:O31613" /db_xref="InterPro:IPR002942" /db_xref="InterPro:IPR006145" /db_xref="InterPro:IPR006224" /db_xref="InterPro:IPR006225" /db_xref="InterPro:IPR020103" /db_xref="SubtiList:BG13144" /db_xref="UniProtKB/Swiss-Prot:O31613" /translation="MTVKEYAGELGISKRLLTDIKFGGGDLQINGEHVTVKYVLKEGD LLIVKFPEEQVSETLLAEPVPLDILYEDEHVLVINKQPYVSSIPSREHPSGSIANGII DHYQTTGVRATVHLVTRLDRDTSGIMLVAKHRFAHSILSSAQKNGLVKRRYAAVVHGR MAQMEGTVDAPIGRHPDSIIERTVTPDGQKAVTHFYVTCANDDMTSVALQLETGRTHQ IRVHMSYLGHPLCGDTLYGGTRQEIGRQALHSEHLSFIHPLTQENMRFHAPLPQDMSK LIKGENH*" gene 1238523..1239374 /gene="yjbO" /locus_tag="BSU_11620" /old_locus_tag="BSU11620" downshifts 1239333 /Source="Nicolas_upshifts" /id="D632" /incds=0 /nref=203 /ntot=256 /MaxReadThrough="0.25796" /MaxDrop="5.73002" /score="21.4914497" /energy="-12.8" /TU="NA" /idTUdmin="U940" /TUdmin=0 /isTUend="TRUE" CDS complement(1239387..1240121) /gene="prpE" /locus_tag="BSU_11630" /old_locus_tag="BSU11630" /EC_number="3.6.1.17" /function="16.3: Control" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:12059787, 16740944, 21092197, 23824080, 28516732" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12059787, 16740944, 21092197, 23824080, 28516732; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="phosphorylated protein phosphatase E and diadenosine-polyphosphate hydrolase" /protein_id="NP_389045.1" /db_xref="EnsemblGenomes-Gn:BSU11630" /db_xref="EnsemblGenomes-Tr:CAB13020" /db_xref="GOA:O31614" /db_xref="InterPro:IPR004843" /db_xref="InterPro:IPR023937" /db_xref="InterPro:IPR029052" /db_xref="SubtiList:BG13145" /db_xref="UniProtKB/Swiss-Prot:O31614" /translation="MAYDIISDIHGCYDEMTALIQKLGYTIKNGVPVHEEGRVLVFAG DLTDRGPKSIEVIRFVAGAYEKGAVRYVPGNHCNKLYRYLKGNPVKVMHGLETTAAEL EELSKDEKKSVSEQFMKLYETAPLYDILHNGELVVAHAGIRADDIGKYTRRVKDFVLY GDVTGETYPDGRPIRRDWAAAYNGKAWVVYGHTPVKEPRKVNRTINIDTGCVFGNQLT GFRFPEIETVSVPSSLPYDESRFRPI*" gene complement(1239387..1240121) /gene="prpE" /locus_tag="BSU_11630" /old_locus_tag="BSU11630" downshifts complement(1239409) /Source="Nicolas_upshifts" /id="D633" /incds=0 /nref=22 /ntot=152 /MaxReadThrough="1.18091" /MaxDrop="3.57735" /score="3.24324561" /energy="-12.8" /TU="NA" /idTUdmin="U938" /TUdmin="-4312" /isTUend="FALSE" promotor_-35 1240243..1240247 /Source="Nicolas_upshift_promotors" /id="U941" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.768231768231768" /psig="0.996003996003996" /xcortree=1820 /SigmaFactorBS="ttctaaacaggattaagaccttatcACTTTatttttcatcat caccCTTGTTAAAATCGCGTTATGttttttaaaaatgaggttttgttctctgagtgag a" /listShort="S419, yjbQ, NA" /listLong="tenA, tenI, thiO, thiS, thiG, thiF, thiD, fabI" /label="promotor_-35" promotor_-10 1240264..1240283 /Source="Nicolas_upshift_promotors" /id="U941" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.768231768231768" /psig="0.996003996003996" /xcortree=1820 /SigmaFactorBS="ttctaaacaggattaagaccttatcACTTTatttttcatcat caccCTTGTTAAAATCGCGTTATGttttttaaaaatgaggttttgttctctgagtgag a" /listShort="S419, yjbQ, NA" /listLong="tenA, tenI, thiO, thiS, thiG, thiF, thiD, fabI" /label="promotor_-10" upshifts 1240278 /Source="Nicolas_upshifts" /id="U941" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.768231768231768" /psig="0.996003996003996" /xcortree=1820 /SigmaFactorBS="ttctaaacaggattaagaccttatcACTTTatttttcatcat caccCTTGTTAAAATCGCGTTATGttttttaaaaatgaggttttgttctctgagtgag a" /listShort="S419, yjbQ, NA" /listLong="tenA, tenI, thiO, thiS, thiG, thiF, thiD, fabI" S_feature 1240279..1240355 /Source="Nicolas_S_feature" /locus_tag="new_1240279_1240355" /HighExp="H2O2, Diami, dia15, Paraq, Oxctl, Heat, G180, Salt, BMM, G135" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.996" /TUlongSig="NA" /TUlongPSig="NA" /label="S419" CDS 1240356..1242200 /gene="kefQ" /locus_tag="BSU_11640" /old_locus_tag="BSU11640" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 15849754, 16850406, 21742892, 24330391; Product type t: transporter" /codon_start=1 /transl_table=11 /product="gated K+/H+ antiporter" /protein_id="NP_389046.1" /db_xref="EnsemblGenomes-Gn:BSU11640" /db_xref="EnsemblGenomes-Tr:CAB13021" /db_xref="GOA:O31615" /db_xref="InterPro:IPR003148" /db_xref="InterPro:IPR006037" /db_xref="InterPro:IPR006153" /db_xref="InterPro:IPR036291" /db_xref="InterPro:IPR036721" /db_xref="SubtiList:BG13146" /db_xref="UniProtKB/Swiss-Prot:O31615" /translation="MAHTSVASLVVVLIVAFLTPILLHRFKLSIPVVVAEIIMGLIIG KSGLNLVVEGDTWLQTLSMLGFIFLMFLSGLEIDFSSFEKGKKKQFLPNGKEAPNTFA AASVIFVGIFILSLLLSYGFVLAGFIQNAFLMTLIISTISLGVVVPTLKEERIMNSNI GQIILLVAVIADLATMILLAVFSSLYGEDSGNMWLLMILFAAGVVLYFFGRVFKHRSF VQSMSKGTIQIGTRAIFTLIIVLVALSESLGAENILGAFLAGVLVSLLSPNKELVQQL DSFGYGFLIPIFFVMVGVKLDIWTLFQDKTILIMIPLLLLALLVSKIIPVMYLKKWYD NRTIFASGFLLTSTLSLVIAAATIGQQLHVISTNMSGALILVAVIASIFTPICFKKLY KREEQPEEKKTITFIGANQMTLPVTLELPEEEYDVRVVHVYQENAEEKLSESVFAVET ISDYEHETLESLGIFETDILVVATGNEDMNADIALLAKDKGTERVIASVGSPEHEAAL KEQGISIFSILLSTKTLLRALIEAPGVMKLLTNQESSLYQINMENSKYDGVILREFPL TGDVIFVRIFRGVDSIVPHGDTRLKLGDRLIVTGSRGYVTDLKKTLEG*" gene 1240356..1242200 /gene="kefQ" /locus_tag="BSU_11640" /old_locus_tag="BSU11640" misc_feature complement(1240683..1240702) /Source="Nicolas_upshift_promotors" /id="U942" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.995004995004995" /psig="0.996003996003996" /xcortree=3108 /SigmaFactorBS="taatcagggtcatcaaaaatgcattttggataaatccggcca agacgaacccataggacaagagcAATGATAAAATAAAAATACCgacgaaaataacaga t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(1240707) /Source="Nicolas_upshifts" /id="U942" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.995004995004995" /psig="0.996003996003996" /xcortree=3108 /SigmaFactorBS="taatcagggtcatcaaaaatgcattttggataaatccggcca agacgaacccataggacaagagcAATGATAAAATAAAAATACCgacgaaaataacaga t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 1242202..1242209 /Source="Nicolas_upshift_promotors" /id="U943" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.878121878121878" /psig="0.999000999001" /xcortree=2884 /SigmaFactorBS="taacggatcttaagaaaacattggaaggataaaTCTTGACCa aataaggattcgTGTTAATATAGAGGTGCAGAacaattcaatatgtattcgtttaacc a" /listShort="NA, tenA, tenI, thiO, thiS, thiG, thiF, thiD" /listLong="fabI" /label="promotor_-35" promotor_-10 1242223..1242242 /Source="Nicolas_upshift_promotors" /id="U943" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.878121878121878" /psig="0.999000999001" /xcortree=2884 /SigmaFactorBS="taacggatcttaagaaaacattggaaggataaaTCTTGACCa aataaggattcgTGTTAATATAGAGGTGCAGAacaattcaatatgtattcgtttaacc a" /listShort="NA, tenA, tenI, thiO, thiS, thiG, thiF, thiD" /listLong="fabI" /label="promotor_-10" upshifts 1242229 /Source="Nicolas_upshifts" /id="U943" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.878121878121878" /psig="0.999000999001" /xcortree=2884 /SigmaFactorBS="taacggatcttaagaaaacattggaaggataaaTCTTGACCa aataaggattcgTGTTAATATAGAGGTGCAGAacaattcaatatgtattcgtttaacc a" /listShort="NA, tenA, tenI, thiO, thiS, thiG, thiF, thiD" /listLong="fabI" misc_RNA 1242262..1242370 /gene="tswA" /locus_tag="BSU_misc_RNA_14" /product="thiamine pyrophosphate riboswitch" /note="Evidence 1c: Function from experimental evidences in the studied genus; PubMedId: 11470904, 12410317, 15862294, 16728979, 16962976, 17307816, 18179415, 18776013; Product type n: RNA" /function="16.3: Control" gene 1242262..1242370 /gene="tswA" /locus_tag="BSU_misc_RNA_14" downshifts 1242365 /Source="Nicolas_upshifts" /id="D634" /incds=0 /nref=20 /ntot=84 /MaxReadThrough="7.67021" /MaxDrop="5.27759" /score="34.8346124" /energy="-12.5" /TU="U943" /idTUdmin="U941" /TUdmin="-4" /isTUend="TRUE" CDS 1242449..1243159 /gene="tenA" /locus_tag="BSU_11650" /old_locus_tag="BSU11650" /EC_number="3.5.99.2" /function="4.11: Thiamine" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:15709744, 15858269, 16356850, 17618314, 18054064, 24311574" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15709744, 15858269, 16356850, 17618314, 18054064, 24311574; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="thiaminase II" /protein_id="NP_389047.1" /db_xref="EnsemblGenomes-Gn:BSU11650" /db_xref="EnsemblGenomes-Tr:CAB13022" /db_xref="GOA:P25052" /db_xref="InterPro:IPR004305" /db_xref="InterPro:IPR016084" /db_xref="InterPro:IPR027574" /db_xref="PDB:1TO9" /db_xref="PDB:1TYH" /db_xref="PDB:1YAF" /db_xref="PDB:1YAK" /db_xref="PDB:2QCX" /db_xref="SubtiList:BG10791" /db_xref="UniProtKB/Swiss-Prot:P25052" /translation="MKFSEECRSAAAEWWEGSFVHPFVQGIGDGTLPIDRFKYYVLQD SYYLTHFAKVQSFGAAYAKDLYTTGRMASHAQGTYEAEMALHREFAELLEISEEERKA FKPSPTAYSYTSHMYRSVLSGNFAEILAALLPCYWLYYEVGEKLLHCDPGHPIYQKWI GTYGGDWFRQQVEEQINRFDELAENSTEEVRAKMKENFVISSYYEYQFWGMAYRKEGW SDSAIKEVEECGASRHNG*" gene 1242449..1243159 /gene="tenA" /locus_tag="BSU_11650" /old_locus_tag="BSU11650" CDS 1243134..1243751 /gene="tenI" /locus_tag="BSU_11660" /old_locus_tag="BSU11660" /EC_number="5.3.99.10" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:15709744, 15858269, 16356850, 21534620" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15709744, 15858269, 16356850, 21534620; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="thiazole tautomerase" /protein_id="NP_389048.1" /db_xref="EnsemblGenomes-Gn:BSU11660" /db_xref="EnsemblGenomes-Tr:CAB13023" /db_xref="GOA:P25053" /db_xref="InterPro:IPR013785" /db_xref="InterPro:IPR022998" /db_xref="InterPro:IPR036206" /db_xref="PDB:1YAD" /db_xref="PDB:3QH2" /db_xref="SubtiList:BG10792" /db_xref="UniProtKB/Swiss-Prot:P25053" /translation="MELHAITDDSKPVEELARIIITIQNEVDFIHIRERSKSAADILK LLDLIFEGGIDKRKLVMNGRVDIALFSTIHRVQLPSGSFSPKQIRARFPHLHIGRSVH SLEEAVQAEKEDADYVLFGHVFETDCKKGLEGRGVSLLSDIKQRISIPVIAIGGMTPD RLRDVKQAGADGIAVMSGIFSSAEPLEAARRYSRKLKEMRYEKAL*" gene 1243134..1243751 /gene="tenI" /locus_tag="BSU_11660" /old_locus_tag="BSU11660" CDS 1243735..1244844 /gene="thiO" /locus_tag="BSU_11670" /old_locus_tag="BSU11670" /EC_number="1.4.3.19" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:9827558, 11744710, 12627963, 15105420, 19751796, 26443755" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9827558, 11744710, 12627963, 15105420, 19751796, 26443755; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="FAD-dependent glycine oxidase" /protein_id="NP_389049.1" /db_xref="EnsemblGenomes-Gn:BSU11670" /db_xref="EnsemblGenomes-Tr:CAB13024" /db_xref="GOA:O31616" /db_xref="InterPro:IPR006076" /db_xref="InterPro:IPR012727" /db_xref="InterPro:IPR036188" /db_xref="PDB:1NG3" /db_xref="PDB:1NG4" /db_xref="PDB:1RYI" /db_xref="PDB:3IF9" /db_xref="SubtiList:BG13147" /db_xref="UniProtKB/Swiss-Prot:O31616" /translation="MKRHYEAVVIGGGIIGSAIAYYLAKENKNTALFESGTMGGRTTS AAAGMLGAHAECEERDAFFDFAMHSQRLYKGLGEELYALSGVDIRQHNGGMFKLAFSE EDVLQLRQMDDLDSVSWYSKEEVLEKEPYASGDIFGASFIQDDVHVEPYFVCKAYVKA AKMLGAEIFEHTPVLHVERDGEALFIKTPSGDVWANHVVVASGVWSGMFFKQLGLNNA FLPVKGECLSVWNDDIPLTKTLYHDHCYIVPRKSGRLVVGATMKPGDWSETPDLGGLE SVMKKAKTMLPAIQNMKVDRFWAGLRPGTKDGKPYIGRHPEDSRILFAAGHFRNGILL APATGALISDLIMNKEVNQDWLHAFRIDRKEAVQI*" gene 1243735..1244844 /gene="thiO" /locus_tag="BSU_11670" /old_locus_tag="BSU11670" CDS 1244844..1245044 /gene="thiS" /locus_tag="BSU_11680" /old_locus_tag="BSU11680" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 10939241, 14567704, 14757766, 15489164, 22616866, 26443755; Product type c : carrier" /codon_start=1 /transl_table=11 /product="sulfur carrier for synthesis of hydroxyethylthiazole phosphate" /protein_id="NP_389050.1" /db_xref="EnsemblGenomes-Gn:BSU11680" /db_xref="EnsemblGenomes-Tr:CAB13025" /db_xref="GOA:O31617" /db_xref="InterPro:IPR003749" /db_xref="InterPro:IPR010035" /db_xref="InterPro:IPR012675" /db_xref="InterPro:IPR016155" /db_xref="PDB:1TYG" /db_xref="SubtiList:BG13148" /db_xref="UniProtKB/Swiss-Prot:O31617" /translation="MLQLNGKDVKWKKDTGTIQDLLASYQLENKIVIVERNKEIIGKE RYHEVELCDRDVIEIVHFVGGG*" gene 1244844..1245044 /gene="thiS" /locus_tag="BSU_11680" /old_locus_tag="BSU11680" CDS 1245041..1245811 /gene="thiG" /locus_tag="BSU_11690" /old_locus_tag="BSU11690" /EC_number="2.8.1.10" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:10939241, 12627963, 14567704, 14757766, 15489164, 22938038" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10939241, 12627963, 14567704, 14757766, 15489164, 22938038; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="hydroxyethylthiazole phosphate synthetase (thiamine biosynthesis)" /protein_id="NP_389051.1" /db_xref="EnsemblGenomes-Gn:BSU11690" /db_xref="EnsemblGenomes-Tr:CAB13026" /db_xref="GOA:O31618" /db_xref="InterPro:IPR008867" /db_xref="InterPro:IPR013785" /db_xref="InterPro:IPR033983" /db_xref="PDB:1TYG" /db_xref="PDB:1XM3" /db_xref="SubtiList:BG13149" /db_xref="UniProtKB/Swiss-Prot:O31618" /translation="MSMLTIGGKSFQSRLLLGTGKYPSFDIQKEAVAVSESDILTFAV RRMNIFEASQPNFLEQLDLSKYTLLPNTAGASTAEEAVRIARLAKASGLCDMIKVEVI GCSRSLLPDPVETLKASEQLLEEGFIVLPYTSDDVVLARKLEELGVHAIMPGASPIGS GQGILNPLNLSFIIEQAKVPVIVDAGIGSPKDAAYAMELGADGVLLNTAVSGADDPVK MARAMKLAVEAGRLSYEAGRIPLKQYGTASSPGEGLPV*" gene 1245041..1245811 /gene="thiG" /locus_tag="BSU_11690" /old_locus_tag="BSU11690" CDS 1245808..1246818 /gene="thiF" /locus_tag="BSU_11700" /old_locus_tag="BSU11700" /EC_number="2.7.7.73" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:10939241, 14567704, 14757766, 15489164, 16388576, 26443755" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10939241, 14567704, 14757766, 15489164, 16388576, 26443755; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="adenylate transferase and sulfur transferase (thiamine biosynthesis)" /protein_id="NP_389052.1" /db_xref="EnsemblGenomes-Gn:BSU11700" /db_xref="EnsemblGenomes-Tr:CAB13027" /db_xref="GOA:O31619" /db_xref="InterPro:IPR000594" /db_xref="InterPro:IPR035985" /db_xref="SubtiList:BG13150" /db_xref="UniProtKB/Swiss-Prot:O31619" /translation="MTGRYSRQELFAPIGPSGQKKLKEARAVIIGAGALGTASAEMLV RAGVGSVKIADRDYVEWSNLQRQQLYTEDDVKKEMPKAAAAERRLRSINSDVDVTGLV MDVTAENIFELIRDASIIVDAADNFETRLIVNDAAVKEGIPFLYGACVGSYGLTFTVV PGSTPCLHCLLDALPIGGATCDTAGIISPAVLQVAVFQVTDALKLLTGEECEPVLRSF DLWKNERSEVRAASLKHDACPSCGTKDFPFLSYENQTKAAVLCGRNTVQIRSSITKEA DLEALAGQLRQAGLEVAANPYLISCRSDDMKMVLFRDGRALIHGTNDIARAKSIYHKW IG*" gene 1245808..1246818 /gene="thiF" /locus_tag="BSU_11700" /old_locus_tag="BSU11700" CDS 1246837..1247652 /gene="thiD" /locus_tag="BSU_11710" /old_locus_tag="BSU11710" /EC_number="2.7.4.7" /EC_number="2.7.1.49" /function="16.11: Scavenge (Catabolism)" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:10939241, 12627963, 14973012, 16952958, 17012797, 26443755" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10939241, 12627963, 14973012, 16952958, 17012797, 26443755; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="phosphomethylpyrimidine kinase, 4-amino-5-hydroxymethyl-2-methylpyrimidine and 4-amino-5-hydroxymethyl-2-methylpyrimidine pyrophosphate kinase" /protein_id="NP_389053.1" /db_xref="EnsemblGenomes-Gn:BSU11710" /db_xref="EnsemblGenomes-Tr:CAB13028" /db_xref="GOA:O31620" /db_xref="InterPro:IPR004399" /db_xref="InterPro:IPR013749" /db_xref="InterPro:IPR029056" /db_xref="SubtiList:BG13151" /db_xref="UniProtKB/Swiss-Prot:O31620" /translation="MSIYKALTIAGSDSGGGAGIQADIKTFQELDVFGMSAITAVTAQ NTLGVHGVHPLTVETLRQQIDAVAEDLRPDAVKTGMLWNADMIEEVARKIDEYGFNRV IVDPVMIAKGGASLLRDESVATLKELLIPRSYAITPNVPEAETLTGMTISSLDDRKKA AEQLVKMGAQHVIIKGGHQPEDNHITDLLFDGSMFMQITHPYINTKHTHGTGCTFAAA LTAQTAKGDSIHQAFEVAANFVREAVENTLGIGSGHGPTNHFAFKRNSLNTSR*" gene 1246837..1247652 /gene="thiD" /locus_tag="BSU_11710" /old_locus_tag="BSU11710" downshifts 1247626 /Source="Nicolas_upshifts" /id="D635" /incds=0 /nref=128 /ntot=172 /MaxReadThrough="3.33485" /MaxDrop="5.0154" /score="3.40314581" /energy="-14.8" /TU="U943" /idTUdmin="U943" /TUdmin="-89" /isTUend="FALSE" promotor_-35 1247699..1247705 /Source="Nicolas_upshift_promotors" /id="U944" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.619380619380619" /psig=1 /xcortree=2189 /SigmaFactorBS="gtgatctcttttgcgtttgctacggtatgcgCTTTTCAtctg gacaaggtTATGATATGATAGGAATTAAgatcaggtactaatactatgtctttattaa a" /listShort="fabI, cotO" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1247718..1247737 /Source="Nicolas_upshift_promotors" /id="U944" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.619380619380619" /psig=1 /xcortree=2189 /SigmaFactorBS="gtgatctcttttgcgtttgctacggtatgcgCTTTTCAtctg gacaaggtTATGATATGATAGGAATTAAgatcaggtactaatactatgtctttattaa a" /listShort="fabI, cotO" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1247728 /Source="Nicolas_upshifts" /id="U944" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.619380619380619" /psig=1 /xcortree=2189 /SigmaFactorBS="gtgatctcttttgcgtttgctacggtatgcgCTTTTCAtctg gacaaggtTATGATATGATAGGAATTAAgatcaggtactaatactatgtctttattaa a" /listShort="fabI, cotO" /GFF_Attribute="listLong" CDS 1247788..1248564 /gene="fabI" /locus_tag="BSU_11720" /old_locus_tag="BSU11720" /EC_number="1.3.1.9" /function="16.2: Construct biomass (Anabolism)" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:11007778, 15105103, 21185310, 25355936" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11007778, 15105103, 21185310, 25355936; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="enoyl-acyl carrier protein reductase" /protein_id="NP_389054.2" /db_xref="EnsemblGenomes-Gn:BSU11720" /db_xref="EnsemblGenomes-Tr:CAB13029" /db_xref="GOA:P54616" /db_xref="InterPro:IPR002347" /db_xref="InterPro:IPR014358" /db_xref="InterPro:IPR036291" /db_xref="PDB:3OIF" /db_xref="PDB:3OIG" /db_xref="SubtiList:BG13152" /db_xref="UniProtKB/Swiss-Prot:P54616" /translation="MNFSLEGRNIVVMGVANKRSIAWGIARSLHEAGARLIFTYAGER LEKSVHELAGTLDRNDSIILPCDVTNDAEIETCFASIKEQVGVIHGIAHCIAFANKEE LVGEYLNTNRDGFLLAHNISSYSLTAVVKAARPMMTEGGSIVTLTYLGGELVMPNYNV MGVAKASLDASVKYLAADLGKENIRVNSISAGPIRTLSAKGISDFNSILKDIEERAPL RRTTTPEEVGDTAAFLFSDMSRGITGENLHVDSGFHITAR*" gene 1247788..1248564 /gene="fabI" /locus_tag="BSU_11720" /old_locus_tag="BSU11720" downshifts 1248553 /Source="Nicolas_upshifts" /id="D636" /incds=0 /nref=229 /ntot=313 /MaxReadThrough="3.12901" /MaxDrop="6.64182" /score="33.5478109" /energy="-11.8" /TU="U944" /idTUdmin="U944" /TUdmin="-416" /isTUend="FALSE" promotor_-35 1248612..1248617 /Source="Nicolas_upshift_promotors" /id="U945" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp="0.968031968031968" /psig="0.968031968031968" /xcortree=1095 /SigmaFactorBS="tcaagcaatcccgaatagggattgcttttttatttCTTCTGa ttttcagctttctgTCATATAGATAGAATATGAcacaatcggagggatgaagatgtct a" /listShort="cotO" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1248633..1248651 /Source="Nicolas_upshift_promotors" /id="U945" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp="0.968031968031968" /psig="0.968031968031968" /xcortree=1095 /SigmaFactorBS="tcaagcaatcccgaatagggattgcttttttatttCTTCTGa ttttcagctttctgTCATATAGATAGAATATGAcacaatcggagggatgaagatgtct a" /listShort="cotO" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1248637 /Source="Nicolas_upshifts" /id="U945" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp="0.968031968031968" /psig="0.968031968031968" /xcortree=1095 /SigmaFactorBS="tcaagcaatcccgaatagggattgcttttttatttCTTCTGa ttttcagctttctgTCATATAGATAGAATATGAcacaatcggagggatgaagatgtct a" /listShort="cotO" /GFF_Attribute="listLong" promotor_-10 complement(1248649..1248663) /Source="Nicolas_upshift_promotors" /id="U946" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.997002997002997" /psig="0.001998001998002" /xcortree=1241 /SigmaFactorBS="gagcggttttttatccgcgtttcttttcttattaGACATctt catcCCTCCGATTGTGTCAtattctatctatatgacagaaagctgaaaatcagaagaa a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1248649) /Source="Nicolas_upshifts" /id="U946" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.997002997002997" /psig="0.001998001998002" /xcortree=1241 /SigmaFactorBS="gagcggttttttatccgcgtttcttttcttattaGACATctt catcCCTCCGATTGTGTCAtattctatctatatgacagaaagctgaaaatcagaagaa a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" CDS 1248665..1249348 /gene="cotO" /locus_tag="BSU_11730" /old_locus_tag="BSU11730" /function="16.13: Shape" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:16321932" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16321932; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="spore outer coat protein" /protein_id="NP_389055.1" /db_xref="EnsemblGenomes-Gn:BSU11730" /db_xref="EnsemblGenomes-Tr:CAB13030" /db_xref="GOA:O31622" /db_xref="InterPro:IPR025439" /db_xref="SubtiList:BG13153" /db_xref="UniProtKB/Swiss-Prot:O31622" /translation="MKMSNKKRNADKKPLMYIVQPDYAETTRSSMQEIVIKRKADKPA PPKAEEKPAYHEKQQEEAVAQDVLQEDQKPAAEPVSQQTQEAREPENIKSQEEQKAEP QAVEETVEHEPPKAEKKEEPALEARKPEKEPEAVHSADKAEEKAPPARKVKKPMSKMT IHEKIDFLTKLPHNMPRALCLIEANGRTYRGVIVGRRNDSVLLRTTGNGAPTELAIDD ITSLHPLGF*" gene 1248665..1249348 /gene="cotO" /locus_tag="BSU_11730" /old_locus_tag="BSU11730" promotor_-35 complement(1248671..1248675) /Source="Nicolas_upshift_promotors" /id="U946" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.997002997002997" /psig="0.001998001998002" /xcortree=1241 /SigmaFactorBS="gagcggttttttatccgcgtttcttttcttattaGACATctt catcCCTCCGATTGTGTCAtattctatctatatgacagaaagctgaaaatcagaagaa a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 1249343 /Source="Nicolas_upshifts" /id="D637" /incds=0 /nref=4 /ntot=40 /MaxReadThrough="3.37645" /MaxDrop="4.6587" /score="18.0229289" /energy="-13.4" /TU="U945" /idTUdmin="U945" /TUdmin="-66" /isTUend="FALSE" downshifts 1249431 /Source="Nicolas_upshifts" /id="D638" /incds=0 /nref=1 /ntot=29 /MaxReadThrough="2.44926" /MaxDrop="4.55934" /score="18.0229289" /energy="-13.4" /TU="NA" /idTUdmin="U945" /TUdmin=22 /isTUend="TRUE" CDS complement(1249442..1249888) /gene="cotZ" /locus_tag="BSU_11740" /old_locus_tag="BSU11740" /function="16.13: Shape" /function="16.8: Protect" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:7519271, 8509331, 19933362, 26341943, 27320701" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7519271, 8509331, 19933362, 26341943, 27320701; Product type s: structure" /codon_start=1 /transl_table=11 /product="spore coat protein (insoluble fraction, crust layer)" /protein_id="NP_389056.1" /db_xref="EnsemblGenomes-Gn:BSU11740" /db_xref="EnsemblGenomes-Tr:CAB13031" /db_xref="GOA:Q08312" /db_xref="InterPro:IPR019593" /db_xref="SubtiList:BG10499" /db_xref="UniProtKB/Swiss-Prot:Q08312" /translation="MSQKTSSCVREAVENIEDLQNAVEEDCPTGCHSKLLSVSHSLGD TVPFAIFTSKSTPLVAFGNVGELDNGPCFNTVFFRVERVHGSCATLSLLIAFDEHKHI LDFTDKDTVCEVFRLEKTNYCIEVDLDCFCAINCLNPRLINRTHHH*" gene complement(1249442..1249888) /gene="cotZ" /locus_tag="BSU_11740" /old_locus_tag="BSU11740" downshifts complement(1249463) /Source="Nicolas_upshifts" /id="D639" /incds=0 /nref=7 /ntot=50 /MaxReadThrough="8.44444" /MaxDrop="7.17581" /score="2.03943557" /energy="-9.3" /TU="U949" /idTUdmin="U950" /TUdmin=0 /isTUend="TRUE" S_feature complement(1249889..1250015) /Source="Nicolas_S_feature" /locus_tag="new_1249889_1250015_c" /HighExp="S8, S7, S6, BT, S5, B36, G/S, Pyr, B60, SMMPr" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigK, SigEF" /TUshortPSig="1, 0.993" /TUlongSig="NA" /TUlongPSig="NA" /label="S420" CDS complement(1250016..1250504) /gene="cotY" /locus_tag="BSU_11750" /old_locus_tag="BSU11750" /function="16.13: Shape" /function="16.8: Protect" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:7519271, 8509331, 14766913, 26341943, 26821119" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7519271, 8509331, 14766913, 26341943, 26821119; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="outer spore coat protein (crust layer, insolublefraction)" /protein_id="NP_389057.1" /db_xref="EnsemblGenomes-Gn:BSU11750" /db_xref="EnsemblGenomes-Tr:CAB13032" /db_xref="GOA:Q08311" /db_xref="InterPro:IPR019593" /db_xref="SubtiList:BG10498" /db_xref="UniProtKB/Swiss-Prot:Q08311" /translation="MSCGKTHGRHENCVCDAVEKILAEQEAVEEQCPTGCYTNLLNPT IAGKDTIPFLVFDKKGGLFSTFGNVGGFVDDMQCFESIFFRVEKLCDCCATLSILRPV DVKGDTLSVCHPCDPDFFGLEKTDFCIEVDLGCFCAIQCLSPELVDRTSPHKDKKHHH NG*" gene complement(1250016..1250504) /gene="cotY" /locus_tag="BSU_11750" /old_locus_tag="BSU11750" promotor_-35 1250184..1250190 /Source="Nicolas_upshift_promotors" /id="U947" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.53046953046953" /psig="0.653346653346653" /xcortree=1630 /SigmaFactorBS="agggtggcaaacacttaaggtATCGCCTttgacatcgaccgg GCGTAAAATAGACAGTGTTGcacagcaatcgcataatttttcgacgcggaagaaaatg g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1250205..1250224 /Source="Nicolas_upshift_promotors" /id="U947" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.53046953046953" /psig="0.653346653346653" /xcortree=1630 /SigmaFactorBS="agggtggcaaacacttaaggtATCGCCTttgacatcgaccgg GCGTAAAATAGACAGTGTTGcacagcaatcgcataatttttcgacgcggaagaaaatg g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1250223 /Source="Nicolas_upshifts" /id="U947" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.53046953046953" /psig="0.653346653346653" /xcortree=1630 /SigmaFactorBS="agggtggcaaacacttaaggtATCGCCTttgacatcgaccgg GCGTAAAATAGACAGTGTTGcacagcaatcgcataatttttcgacgcggaagaaaatg g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 1250500..1250504 /Source="Nicolas_upshift_promotors" /id="U948" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.997002997002997" /psig="0.002997002997003" /xcortree=1244 /SigmaFactorBS="tctcatgccggccatgggtttttccgcagCTCATtgatttca GCTCCTTCTTTATAGggtatttgactttagtccttaacaacatatgtacccgtgcccc a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1250513..1250527 /Source="Nicolas_upshift_promotors" /id="U948" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.997002997002997" /psig="0.002997002997003" /xcortree=1244 /SigmaFactorBS="tctcatgccggccatgggtttttccgcagCTCATtgatttca GCTCCTTCTTTATAGggtatttgactttagtccttaacaacatatgtacccgtgcccc a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1250531 /Source="Nicolas_upshifts" /id="U948" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.997002997002997" /psig="0.002997002997003" /xcortree=1244 /SigmaFactorBS="tctcatgccggccatgggtttttccgcagCTCATtgatttca GCTCCTTCTTTATAGggtatttgactttagtccttaacaacatatgtacccgtgcccc a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 complement(1250541..1250560) /Source="Nicolas_upshift_promotors" /id="U949" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1280 /SigmaFactorBS="tattttccaagcatatgatgaatatatagacgttcACCCACA CCAagtggggcacgggTACATATGTTGTTAAGGACTaaagtcaaataccctataaaga a" /listShort="cotY, S420, cotZ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1250558) /Source="Nicolas_upshifts" /id="U949" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1280 /SigmaFactorBS="tattttccaagcatatgatgaatatatagacgttcACCCACA CCAagtggggcacgggTACATATGTTGTTAAGGACTaaagtcaaataccctataaaga a" /listShort="cotY, S420, cotZ" /GFF_Attribute="listLong" promotor_-35 complement(1250574..1250583) /Source="Nicolas_upshift_promotors" /id="U949" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1280 /SigmaFactorBS="tattttccaagcatatgatgaatatatagacgttcACCCACA CCAagtggggcacgggTACATATGTTGTTAAGGACTaaagtcaaataccctataaaga a" /listShort="cotY, S420, cotZ" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(1250590..1250608) /Source="Nicolas_upshift_promotors" /id="U950" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.993006993006993" /psig="0.993006993006993" /xcortree=1006 /SigmaFactorBS="cttgtcctctaggacctaaaagcagagctaaaaacgctCTGC TTtttcttattttccaaGCATATGATGAATATATAGacgttcacccacaccaagtggg g" /listShort="cotY, S420, cotZ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1250607) /Source="Nicolas_upshifts" /id="U950" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.993006993006993" /psig="0.993006993006993" /xcortree=1006 /SigmaFactorBS="cttgtcctctaggacctaaaagcagagctaaaaacgctCTGC TTtttcttattttccaaGCATATGATGAATATATAGacgttcacccacaccaagtggg g" /listShort="cotY, S420, cotZ" /GFF_Attribute="listLong" promotor_-35 complement(1250624..1250629) /Source="Nicolas_upshift_promotors" /id="U950" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.993006993006993" /psig="0.993006993006993" /xcortree=1006 /SigmaFactorBS="cttgtcctctaggacctaaaagcagagctaaaaacgctCTGC TTtttcttattttccaaGCATATGATGAATATATAGacgttcacccacaccaagtggg g" /listShort="cotY, S420, cotZ" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 1250641 /Source="Nicolas_upshifts" /id="D640" /incds=0 /nref=1 /ntot=14 /MaxReadThrough="1.28604" /MaxDrop="4.18677" /score="-9.76125107" /energy="-10.4" /TU="NA" /idTUdmin="U948" /TUdmin=22 /isTUend="TRUE" CDS complement(1250656..1251174) /gene="cotX" /locus_tag="BSU_11760" /old_locus_tag="BSU11760" /function="16.13: Shape" /function="16.8: Protect" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:7519271, 8509331, 10400595, 10788508, 12031481, 19304857, 26821119" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7519271, 8509331, 10400595, 10788508, 12031481, 19304857, 26821119; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="spore coat protein (insoluble fraction)" /protein_id="NP_389058.1" /db_xref="EnsemblGenomes-Gn:BSU11760" /db_xref="EnsemblGenomes-Tr:CAB13033" /db_xref="GOA:Q08313" /db_xref="InterPro:IPR011428" /db_xref="SubtiList:BG10500" /db_xref="UniProtKB/Swiss-Prot:Q08313" /translation="MESRPYSWVALDPDCDHPLDDKEKDKEKHERKCHCDVCCNGNGF FGNDNAFIDQDLAQANLNKQVSDETIIIRDSCDINVTSTDVQAVTSVVTALNAAVVTA TLTSIADGVIAELVAQDLLQLTANKQVNRQKLLIECSRGVNVTTVDADIATLISTATN TLVAILVITLVL*" gene complement(1250656..1251174) /gene="cotX" /locus_tag="BSU_11760" /old_locus_tag="BSU11760" downshifts complement(1250680) /Source="Nicolas_upshifts" /id="D641" /incds=0 /nref=76 /ntot=102 /MaxReadThrough="1.79219" /MaxDrop="8.69761" /score="18.5755652" /energy="-10.4" /TU="U952" /idTUdmin="U952" /TUdmin="-29" /isTUend="FALSE" downshifts 1250685 /Source="Nicolas_upshifts" /id="D642" /incds=0 /nref=1 /ntot=8 /MaxReadThrough="1.2156" /MaxDrop="3.69222" /score="-9.76125107" /energy="-10.4" /TU="NA" /idTUdmin="U948" /TUdmin=66 /isTUend="FALSE" S_feature complement(1251175..1251272) /Source="Nicolas_S_feature" /locus_tag="new_1251175_1251272_c" /HighExp="S8, S7, S6, BT, B36, G/S, Pyr, S5, B60, SMMPr" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigK" /TUshortPSig="0.748" /TUlongSig="SigK" /TUlongPSig="0.98" /label="S421" CDS complement(1251273..1251590) /gene="cotW" /locus_tag="BSU_11770" /old_locus_tag="BSU11770" /function="16.5: Explore" /function="16.13: Shape" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:8509331, 19304857, 21665972, 25872412" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8509331, 19304857, 21665972, 25872412; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="spore coat protein (outemost layer)" /protein_id="NP_389059.1" /db_xref="EnsemblGenomes-Gn:BSU11770" /db_xref="EnsemblGenomes-Tr:CAB13034" /db_xref="GOA:Q08310" /db_xref="SubtiList:BG10497" /db_xref="UniProtKB/Swiss-Prot:Q08310" /translation="MSDNDKFKEELAKLPEVDPMTKMLVQNIFSKHGVTKDKMKKVSD EEKEMLLNLVKDLQAKSQALIENQKKKKEEAAAQEQKNTKPLSRREQLIEQIRQRRKN DNN*" gene complement(1251273..1251590) /gene="cotW" /locus_tag="BSU_11770" /old_locus_tag="BSU11770" CDS complement(1251631..1252017) /gene="cotV" /locus_tag="BSU_11780" /old_locus_tag="BSU11780" /function="16.13: Shape" /function="16.8: Protect" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:7519271, 8509331" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7519271, 8509331; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="spore coat protein (insoluble fraction)" /protein_id="NP_389060.1" /db_xref="EnsemblGenomes-Gn:BSU11780" /db_xref="EnsemblGenomes-Tr:CAB13035" /db_xref="GOA:Q08309" /db_xref="InterPro:IPR011428" /db_xref="SubtiList:BG10496" /db_xref="UniProtKB/Swiss-Prot:Q08309" /translation="MSFEEKVESLHPAIFEQLSSEFEQQIEVIDCENITIDTSHITAA LSIQAFVTTMIIVATQLVIADEDLADAVASEILILDSSQIKKRTIIKIINSRNIKITL SADEIITFVQILLQVLNSILSELDVL*" gene complement(1251631..1252017) /gene="cotV" /locus_tag="BSU_11780" /old_locus_tag="BSU11780" promotor_-35 1252013..1252017 /Source="Nicolas_upshift_promotors" /id="U951" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.99100899100899" /psig="0.005994005994006" /xcortree=1245 /SigmaFactorBS="ttgctcaaatattgcagggtgcagggattcgactttttcttc aaatGACATaaccttcACTCCTTTCTTATCCatactctatataatgcaaatggggtgc a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1252025..1252039 /Source="Nicolas_upshift_promotors" /id="U951" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.99100899100899" /psig="0.005994005994006" /xcortree=1245 /SigmaFactorBS="ttgctcaaatattgcagggtgcagggattcgactttttcttc aaatGACATaaccttcACTCCTTTCTTATCCatactctatataatgcaaatggggtgc a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1252027 /Source="Nicolas_upshifts" /id="U951" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.99100899100899" /psig="0.005994005994006" /xcortree=1245 /SigmaFactorBS="ttgctcaaatattgcagggtgcagggattcgactttttcttc aaatGACATaaccttcACTCCTTTCTTATCCatactctatataatgcaaatggggtgc a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 complement(1252037..1252056) /Source="Nicolas_upshift_promotors" /id="U952" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp="0.748251748251748" /psig="0.748251748251748" /xcortree=1351 /SigmaFactorBS="catgaattgtatcttgtccggcagaaaattggttatttttat taTtCcGctctgcaccccattTGCATTATATAGAGTATGGAtaagaaaggagtgaagg t" /listShort="cotV, cotW, S421, cotX" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1252059) /Source="Nicolas_upshifts" /id="U952" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp="0.748251748251748" /psig="0.748251748251748" /xcortree=1351 /SigmaFactorBS="catgaattgtatcttgtccggcagaaaattggttatttttat taTtCcGctctgcaccccattTGCATTATATAGAGTATGGAtaagaaaggagtgaagg t" /listShort="cotV, cotW, S421, cotX" /GFF_Attribute="listLong" S_feature complement(1252061..1252565) /Source="Nicolas_S_feature" /locus_tag="new_1252061_1252565_c" /HighExp="S8, S6, S7, BT, S5, B36, Pyr, C30, G/S, nit" /AntisenseName="yjcA" /AntisenseCor="0.69838474492609404" /AntisenseRegPval="-39.9" /CDS_PredictionProba="NA" /TUshortSig="SigK" /TUshortPSig="0.98" /TUlongSig="NA" /TUlongPSig="NA" /label="S422" promotor_-35 complement(1252075) /Source="Nicolas_upshift_promotors" /id="U952" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp="0.748251748251748" /psig="0.748251748251748" /xcortree=1351 /SigmaFactorBS="catgaattgtatcttgtccggcagaaaattggttatttttat taTtCcGctctgcaccccattTGCATTATATAGAGTATGGAtaagaaaggagtgaagg t" /listShort="cotV, cotW, S421, cotX" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1252114..1252119 /Source="Nicolas_upshift_promotors" /id="U953" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1132 /SigmaFactorBS="aataaaaataaccaattttctgccggacaagatacaaTTCAT GaagaatagggttttgGCATATATGTGAAGGGATCatgattggcaaaggagtgaacga g" /listShort="yjcA, S423" /listLong="yjzK, yjcZ, S424, spoVIF, S425" /label="promotor_-35" promotor_-10 1252135..1252153 /Source="Nicolas_upshift_promotors" /id="U953" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1132 /SigmaFactorBS="aataaaaataaccaattttctgccggacaagatacaaTTCAT GaagaatagggttttgGCATATATGTGAAGGGATCatgattggcaaaggagtgaacga g" /listShort="yjcA, S423" /listLong="yjzK, yjcZ, S424, spoVIF, S425" /label="promotor_-10" upshifts 1252137 /Source="Nicolas_upshifts" /id="U953" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1132 /SigmaFactorBS="aataaaaataaccaattttctgccggacaagatacaaTTCAT GaagaatagggttttgGCATATATGTGAAGGGATCatgattggcaaaggagtgaacga g" /listShort="yjcA, S423" /listLong="yjzK, yjcZ, S424, spoVIF, S425" CDS 1252177..1252533 /gene="yjcA" /locus_tag="BSU_11790" /old_locus_tag="BSU11790" /function="16.8: Protect" /function="16.13: Shape" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:14523132, 15849754, 16850406" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 14523132, 15849754, 16850406; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="sporulation-specific protein" /protein_id="NP_389061.1" /db_xref="EnsemblGenomes-Gn:BSU11790" /db_xref="EnsemblGenomes-Tr:CAB13036" /db_xref="GOA:O31623" /db_xref="InterPro:IPR010773" /db_xref="SubtiList:BG13154" /db_xref="UniProtKB/Swiss-Prot:O31623" /translation="MVINGLTIVLLSLAVFRLARLLVFDTIMAPLRSLFHEEKEEKDA DGNIETYIVIKGTGVRAFIGELLSCYWCTGVWCAGFLILCQAVIPQAAQWLILLLAIA GLAGIIETLVSKWLQE*" gene 1252177..1252533 /gene="yjcA" /locus_tag="BSU_11790" /old_locus_tag="BSU11790" promotor_-35 1252543..1252552 /Source="Nicolas_upshift_promotors" /id="U955" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1353 /SigmaFactorBS="gctcgtatcaaaatggctgcaagaataaggcgttaccACCAG CAACTttctgtcagaataCGCATAAAGTAGCATATAtgacataaggaaaggaagggga c" /listShort="S423, yjzK" /listLong="yjcZ, S424, spoVIF, S425" /label="promotor_-35" promotor_-10 complement(1252550..1252569) /Source="Nicolas_upshift_promotors" /id="U954" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.98001998001998" /psig="0.98001998001998" /xcortree=1256 /SigmaFactorBS="atgatgctgattcatttttgtccccttcctttcCTTATGTCA TatatgctactttaTGCGTATTCTGACAGAAAGTtgctggtggtaacgccttattctt g" /listShort="S422" /listLong="cotV, cotW, S421, cotX" /label="promotor_-10" CDS complement(1252558..1252791) /locus_tag="BSU_11798" /old_locus_tag="BSU11798" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /pseudo /codon_start=1 /transl_table=11 /product="protein remnant" /db_xref="PSEUDO:SOX90549.1" /translation="MLSETASLKKQKTGVLRFLCQAIEAFSFYFRTRSLSFLSFLIDT MNLYMEIFGKVYDADSFLSPSFPYVIYATLCVF*" gene complement(1252558..1252791) /locus_tag="BSU_11798" /old_locus_tag="BSU11798" /pseudo upshifts complement(1252565) /Source="Nicolas_upshifts" /id="U954" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.98001998001998" /psig="0.98001998001998" /xcortree=1256 /SigmaFactorBS="atgatgctgattcatttttgtccccttcctttcCTTATGTCA TatatgctactttaTGCGTATTCTGACAGAAAGTtgctggtggtaacgccttattctt g" /listShort="S422" /listLong="cotV, cotW, S421, cotX" S_feature 1252566..1252752 /Source="Nicolas_S_feature" /locus_tag="new_1252566_1252752" /HighExp="S8, S6, S7, BT, S5, B36, S4, S3, G/S, Pyr" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.26970100000000002" /TUshortSig="SigK, SigEF" /TUshortPSig="0.999, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S423" promotor_-10 1252566..1252583 /Source="Nicolas_upshift_promotors" /id="U955" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1353 /SigmaFactorBS="gctcgtatcaaaatggctgcaagaataaggcgttaccACCAG CAACTttctgtcagaataCGCATAAAGTAGCATATAtgacataaggaaaggaagggga c" /listShort="S423, yjzK" /listLong="yjcZ, S424, spoVIF, S425" /label="promotor_-10" upshifts 1252566 /Source="Nicolas_upshifts" /id="U955" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1353 /SigmaFactorBS="gctcgtatcaaaatggctgcaagaataaggcgttaccACCAG CAACTttctgtcagaataCGCATAAAGTAGCATATAtgacataaggaaaggaagggga c" /listShort="S423, yjzK" /listLong="yjcZ, S424, spoVIF, S425" promotor_-35 complement(1252583..1252592) /Source="Nicolas_upshift_promotors" /id="U954" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.98001998001998" /psig="0.98001998001998" /xcortree=1256 /SigmaFactorBS="atgatgctgattcatttttgtccccttcctttcCTTATGTCA TatatgctactttaTGCGTATTCTGACAGAAAGTtgctggtggtaacgccttattctt g" /listShort="S422" /listLong="cotV, cotW, S421, cotX" /label="promotor_-35" downshifts complement(1252609) /Source="Nicolas_upshifts" /id="D643" /incds=0 /nref=2 /ntot=13 /MaxReadThrough="3.12564" /MaxDrop="4.58782" /score="-6.14331629" /energy="-6.8" /TU="NA" /idTUdmin="U954" /TUdmin="-528" /isTUend="FALSE" downshifts 1252709 /Source="Nicolas_upshifts" /id="D644" /incds=0 /nref=3 /ntot=32 /MaxReadThrough="5.73879" /MaxDrop="3.6919" /score="33.8150878" /energy="-6.8" /TU="U953,U955" /idTUdmin="U953" /TUdmin="-66" /isTUend="FALSE" upshifts complement(1252763) /Source="Nicolas_upshifts" /id="U956" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.284715284715285" /psig="0.032967032967033" /xcortree=768 /SigmaFactorBS="ctcattcacttttatccccccgcttatgatatatgctgagcg agaCCGCCTCGttaaaaaaacaaaaaaccggagttctccggtttctttgccaggctat t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 1252764..1252773 /Source="Nicolas_upshift_promotors" /id="U957" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp="0.971028971028971" /psig="0.971028971028971" /xcortree=1288 /SigmaFactorBS="gaaaccggagaactccggttttttgttTTTTTAACGAggcgg tctcgctcAGCATATATCATAAGCGGGGggataaaagtgaatgagtttgaaaaatgga t" /listShort="yjzK, yjcZ, S424, spoVIF, S425" /GFF_Attribute="listLong" /label="promotor_-35" misc_feature complement(1252771..1252778) /Source="Nicolas_upshift_promotors" /id="U956" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.284715284715285" /psig="0.032967032967033" /xcortree=768 /SigmaFactorBS="ctcattcacttttatccccccgcttatgatatatgctgagcg agaCCGCCTCGttaaaaaaacaaaaaaccggagttctccggtttctttgccaggctat t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" promotor_-10 1252787..1252806 /Source="Nicolas_upshift_promotors" /id="U957" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp="0.971028971028971" /psig="0.971028971028971" /xcortree=1288 /SigmaFactorBS="gaaaccggagaactccggttttttgttTTTTTAACGAggcgg tctcgctcAGCATATATCATAAGCGGGGggataaaagtgaatgagtttgaaaaatgga t" /listShort="yjzK, yjcZ, S424, spoVIF, S425" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1252797 /Source="Nicolas_upshifts" /id="U957" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp="0.971028971028971" /psig="0.971028971028971" /xcortree=1288 /SigmaFactorBS="gaaaccggagaactccggttttttgttTTTTTAACGAggcgg tctcgctcAGCATATATCATAAGCGGGGggataaaagtgaatgagtttgaaaaatgga t" /listShort="yjzK, yjcZ, S424, spoVIF, S425" /GFF_Attribute="listLong" CDS 1252815..1253021 /gene="yjzK" /locus_tag="BSU_11799" /old_locus_tag="BSU11799" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="YP_003097704.1" /db_xref="EnsemblGenomes-Gn:BSU11799" /db_xref="EnsemblGenomes-Tr:CAX52594" /db_xref="UniProtKB/Swiss-Prot:C0H3Y7" /translation="MNEFEKWIEGRYEPHEQKQKEHEDTMGSIRKDLDAFDKAGLEFE DEIEELAEKTEALLKKHQAQYDQS*" gene 1252815..1253021 /gene="yjzK" /locus_tag="BSU_11799" /old_locus_tag="BSU11799" CDS 1252858..1253073 /gene="yjcB" /locus_tag="BSU_11800" /old_locus_tag="BSU11800" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:14523132" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 14523132; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="sporulation-specific protein" /protein_id="YP_009513951.1" /translation="MNKSKKSMKTRWAVSEKTWMHLIKPVWNLKMRLKSWLKKRRPYL KNIKLNMINRKSANALCEYPSRSQQLT*" gene 1252858..1253073 /gene="yjcB" /locus_tag="BSU_11800" /old_locus_tag="BSU11800" promotor_-35 1253045..1253054 /Source="Nicolas_upshift_promotors" /id="U958" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1409 /SigmaFactorBS="tcaatcgtaaatccgcaaacgccctatgcgaatATCCAAGCC GatcccagcagctCACATAGTGTATAGAGAGTAaaggaggtgcttatctatgggcttt g" /listShort="yjcZ, S424, spoVIF, S425" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1253067..1253086 /Source="Nicolas_upshift_promotors" /id="U958" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1409 /SigmaFactorBS="tcaatcgtaaatccgcaaacgccctatgcgaatATCCAAGCC GatcccagcagctCACATAGTGTATAGAGAGTAaaggaggtgcttatctatgggcttt g" /listShort="yjcZ, S424, spoVIF, S425" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1253072 /Source="Nicolas_upshifts" /id="U958" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1409 /SigmaFactorBS="tcaatcgtaaatccgcaaacgccctatgcgaatATCCAAGCC GatcccagcagctCACATAGTGTATAGAGAGTAaaggaggtgcttatctatgggcttt g" /listShort="yjcZ, S424, spoVIF, S425" /GFF_Attribute="listLong" promotor_-10 complement(1253079..1253093) /Source="Nicolas_upshift_promotors" /id="U959" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.999000999001" /psig=0 /xcortree=690 /SigmaFactorBS="gccataacagccgccgccgtagccgccgccgaatccgtatcc aaagCCCATagataagcaCCTCCTTTACTCTCTatacactatgtgagctgctgggatc g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1253093) /Source="Nicolas_upshifts" /id="U959" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.999000999001" /psig=0 /xcortree=690 /SigmaFactorBS="gccataacagccgccgccgtagccgccgccgaatccgtatcc aaagCCCATagataagcaCCTCCTTTACTCTCTatacactatgtgagctgctgggatc g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(1253103..1253107) /Source="Nicolas_upshift_promotors" /id="U959" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.999000999001" /psig=0 /xcortree=690 /SigmaFactorBS="gccataacagccgccgccgtagccgccgccgaatccgtatcc aaagCCCATagataagcaCCTCCTTTACTCTCTatacactatgtgagctgctgggatc g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" CDS 1253103..1253252 /gene="yjcZ" /locus_tag="BSU_11809" /old_locus_tag="BSU11809" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 14523132, 20156992, 21670523; Product type h: extrachromosomal origin" /codon_start=1 /transl_table=11 /product="putative type I toxin" /protein_id="YP_003097705.1" /db_xref="EnsemblGenomes-Gn:BSU11809" /db_xref="EnsemblGenomes-Tr:CAX52595" /db_xref="GOA:C0H3Y8" /db_xref="InterPro:IPR010070" /db_xref="UniProtKB/Swiss-Prot:C0H3Y8" /translation="MGFGYGFGGGYGGGCYGGYAGGYGGGYGSTFVLLVVLFILLIIV GASFF*" gene 1253103..1253252 /gene="yjcZ" /locus_tag="BSU_11809" /old_locus_tag="BSU11809" downshifts 1253193 /Source="Nicolas_upshifts" /id="D645" /incds=0 /nref=4 /ntot=29 /MaxReadThrough="8.16203" /MaxDrop="4.48861" /score="1.53429015" /energy="-22.4" /TU="U957,U958" /idTUdmin="U955" /TUdmin=110 /isTUend="FALSE" S_feature 1253253..1253384 /Source="Nicolas_S_feature" /locus_tag="new_1253253_1253384" /HighExp="S7, BT, S8, B36, S6, G/S, Pyr, B60, S5, LoTm" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigK, SigK" /TUshortPSig="1, 0.971" /TUlongSig="SigK, SigEF" /TUlongPSig="0.999, 1" /label="S424" CDS 1253385..1253639 /gene="spoVIF" /locus_tag="BSU_11810" /old_locus_tag="BSU11810" /function="16.8: Protect" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:14523132, 14702409, 20435725" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 14523132, 14702409, 20435725; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="sporulation-specific protein needed for heat resistance" /protein_id="NP_389063.2" /db_xref="EnsemblGenomes-Gn:BSU11810" /db_xref="EnsemblGenomes-Tr:CAB13038" /db_xref="GOA:O31625" /db_xref="InterPro:IPR025942" /db_xref="SubtiList:BG13156" /db_xref="UniProtKB/Swiss-Prot:O31625" /translation="MDNQFFKNIEKKTGVKMQDVMNLAGSLQNANFKDENTVRSVINR VAQMANRRVPKELEDKIVESITSGKEKLDFGTISKMMDNK*" gene 1253385..1253639 /gene="spoVIF" /locus_tag="BSU_11810" /old_locus_tag="BSU11810" downshifts 1253624 /Source="Nicolas_upshifts" /id="D646" /incds=0 /nref=40 /ntot=79 /MaxReadThrough="5.66609" /MaxDrop="5.8411" /score="7.68851688" /energy="-10.7" /TU="U957,U958" /idTUdmin="U955" /TUdmin=541 /isTUend="FALSE" downshifts complement(1253643) /Source="Nicolas_upshifts" /id="D647" /incds=0 /nref=3 /ntot=9 /MaxReadThrough="3.12148" /MaxDrop="4.34051" /score="24.4726468" /energy="-14.3" /TU="NA" /idTUdmin="U961" /TUdmin=88 /isTUend="FALSE" S_feature 1253669..1254769 /Source="Nicolas_S_feature" /locus_tag="new_1253669_1254769" /HighExp="S8, S6, S7, B36, S5, C30, BT, dia15, Diami, H2O2" /AntisenseName="yjcD" /AntisenseCor="-0.210610370451118" /AntisenseRegPval="-3.3" /CDS_PredictionProba="0.18426200000000001" /TUshortSig="SigK, SigK" /TUshortPSig="1, 0.971" /TUlongSig="SigK, SigEF" /TUlongPSig="0.999, 1" /label="S425" CDS complement(1253713..1255992) /gene="yjcD" /locus_tag="BSU_11820" /old_locus_tag="BSU11820" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 11544244, 16014871, 17114254, 22933559; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative ATP-dependent DNA helicase (sporulationassociated)" /protein_id="NP_389064.3" /db_xref="EnsemblGenomes-Gn:BSU11820" /db_xref="EnsemblGenomes-Tr:CAB13039" /db_xref="GOA:O31626" /db_xref="InterPro:IPR000212" /db_xref="InterPro:IPR014016" /db_xref="InterPro:IPR014017" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR034739" /db_xref="SubtiList:BG13157" /db_xref="UniProtKB/Swiss-Prot:O31626" /translation="MKCARLNDRIIHLHTYSREHYQFLFEEGIKGHLFCSHCGKPVLL RLNIADPPEFIHRQPGDFPACEEACEPKPSKEGKKEDDQESGVIRLPKGKAIAADPSP AVTEWHRPRSIKPGTPFVPKTIEPDTSLFPSVGLNTDQLKAVTETEGPLLVLAGAGSG KTRVLTARAAHMIEHLGIPPENMLLVTFTTKAVAEMKERMANQYGLQPAKVRRIVTGT FHSLFYKILYHSNSAKWNGEHLLKMEWQREQYIKKALYEEGIDEKESPVDQALQQIGF WKNTYVPNERIPLKDEWEKQVYRLYEHYERQKKEHSQFDFDDMASACYELFIERPDLL EQYQSRFTYILIDEFQDINPVQYKIMQMLASPEQNLCCVGDDDQSIYAFRGSNPSFIL DFQKDYPGAKTIYLTANYRSTHPIVSSADIVVKKNKNRYAKTLEAARDDIQVPVLFYP YDEEEEATMVVSDIKEKIQNGASPEDFAVLYRTNSGGRAIYERLHQSSIPYTADRGVQ SFYSRRIVRQILAYLYASQNEDDTEAIKHLLPALFLKQSALNTLKALSITEDCTMIKA LAKLPDLKPFQLDKIKKIVPFFASLRTMKPVEAITFAEGKMGFSEYLKKRGNEGNKLE KGSDDLRDIKVVAKKFKTIPDFLAHVDHMRAAEKNRTDEHGVQLMTIHRSKGLEFKTV YVLGTVDGSIPHDFSLETARKGDEAALEEERRLLYVAMTRAKQHLYLSCPANRRGKTA NRSRFLYPLLQKARQPLHH*" gene complement(1253713..1255992) /gene="yjcD" /locus_tag="BSU_11820" /old_locus_tag="BSU11820" downshifts complement(1253731) /Source="Nicolas_upshifts" /id="D648" /incds=0 /nref=61 /ntot=171 /MaxReadThrough="2.59869" /MaxDrop="4.36061" /score="24.4726468" /energy="-14.3" /TU="NA" /idTUdmin="U961" /TUdmin=0 /isTUend="TRUE" S_feature complement(1255867..1256041) /Source="Nicolas_S_feature" /locus_tag="new_1255867_1256041_c" /HighExp="G180, G135, G150, H2O2, Paraq, Oxctl, LBGexp, dia15, dia0, MG 15" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S426" promotor_-35 1255920..1255928 /Source="Nicolas_upshift_promotors" /id="U960" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.868131868131868" /psig="0.868131868131868" /xcortree=958 /SigmaFactorBS="tgagaacaaaataaatgtccttttattccctcttcaaAGAGG AATTgataatgttcTCTCGAATATGTATGTAAAtgtatgattctatcattcagtcggg c" /listShort="S427, yjzE" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1255939..1255957 /Source="Nicolas_upshift_promotors" /id="U960" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.868131868131868" /psig="0.868131868131868" /xcortree=958 /SigmaFactorBS="tgagaacaaaataaatgtccttttattccctcttcaaAGAGG AATTgataatgttcTCTCGAATATGTATGTAAAtgtatgattctatcattcagtcggg c" /listShort="S427, yjzE" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 1255943..1256078 /Source="Nicolas_S_feature" /locus_tag="new_1255943_1256078" /HighExp="S4, S5, S3, S6, S7, S8, M9-stat, T4.0H, T3.0H, S2" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigH" /TUshortPSig="0.868" /TUlongSig="NA" /TUlongPSig="NA" /label="S427" upshifts 1255943 /Source="Nicolas_upshifts" /id="U960" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.868131868131868" /psig="0.868131868131868" /xcortree=958 /SigmaFactorBS="tgagaacaaaataaatgtccttttattccctcttcaaAGAGG AATTgataatgttcTCTCGAATATGTATGTAAAtgtatgattctatcattcagtcggg c" /listShort="S427, yjzE" /GFF_Attribute="listLong" promotor_-10 complement(1256029..1256048) /Source="Nicolas_upshift_promotors" /id="U961" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.987012987012987" /psig=1 /xcortree=2545 /SigmaFactorBS="cacccctctgctgtctcttttcccttaaacttACTTTttgaa acacatttctTTTGATATGATAGTCATTGTctgtaatgaacaccttttgattgggagg a" /listShort="S426, yjcD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1256040) /Source="Nicolas_upshifts" /id="U961" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.987012987012987" /psig=1 /xcortree=2545 /SigmaFactorBS="cacccctctgctgtctcttttcccttaaacttACTTTttgaa acacatttctTTTGATATGATAGTCATTGTctgtaatgaacaccttttgattgggagg a" /listShort="S426, yjcD" /GFF_Attribute="listLong" promotor_-35 1256056..1256062 /Source="Nicolas_upshift_promotors" /id="U962" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=197 /SigmaFactorBS="tcattacagacaatgactatcatatcaaaagaaatgTGTTTC AaaaagtaagtttaaGGGAAAAGAGACAGCAGAGgggtgggtattgtatgatatatgc a" /listShort="yjzE" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 complement(1256064..1256068) /Source="Nicolas_upshift_promotors" /id="U961" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.987012987012987" /psig=1 /xcortree=2545 /SigmaFactorBS="cacccctctgctgtctcttttcccttaaacttACTTTttgaa acacatttctTTTGATATGATAGTCATTGTctgtaatgaacaccttttgattgggagg a" /listShort="S426, yjcD" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1256077..1256095 /Source="Nicolas_upshift_promotors" /id="U962" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=197 /SigmaFactorBS="tcattacagacaatgactatcatatcaaaagaaatgTGTTTC AaaaagtaagtttaaGGGAAAAGAGACAGCAGAGgggtgggtattgtatgatatatgc a" /listShort="yjzE" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1256080 /Source="Nicolas_upshifts" /id="U962" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=197 /SigmaFactorBS="tcattacagacaatgactatcatatcaaaagaaatgTGTTTC AaaaagtaagtttaaGGGAAAAGAGACAGCAGAGgggtgggtattgtatgatatatgc a" /listShort="yjzE" /GFF_Attribute="listLong" CDS 1256109..1256363 /gene="yjzE" /locus_tag="BSU_11839" /old_locus_tag="BSU11839" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function; PubMedId : 11976315, 23155385" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_003097706.1" /db_xref="EnsemblGenomes-Gn:BSU11839" /db_xref="EnsemblGenomes-Tr:CAX52596" /db_xref="UniProtKB/Swiss-Prot:C0H3Y9" /translation="MIYAGQIQNQQYAQYANRTIGHKQDYAGTEKISYVPFQRVYKEL EKQQENQTAAERKVNEMKRKRSLYKRLREKGMGTYINRYV*" gene 1256109..1256363 /gene="yjzE" /locus_tag="BSU_11839" /old_locus_tag="BSU11839" downshifts 1256339 /Source="Nicolas_upshifts" /id="D649" /incds=0 /nref=101 /ntot=248 /MaxReadThrough="3.69482" /MaxDrop="7.80206" /score="5.37568515" /energy="-6.1" /TU="U962" /idTUdmin="U960" /TUdmin=0 /isTUend="TRUE" downshifts complement(1256429) /Source="Nicolas_upshifts" /id="D650" /incds=0 /nref=78 /ntot=283 /MaxReadThrough="3.21062" /MaxDrop="7.8562" /score="-4.05705392" /energy="-6.1" /TU="U963" /idTUdmin="U963" /TUdmin="-36" /isTUend="FALSE" CDS complement(1256436..1256858) /gene="yjcF" /locus_tag="BSU_11840" /old_locus_tag="BSU11840" /EC_number="2.3.1.-" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative acetyltransferase" /protein_id="NP_389066.1" /db_xref="EnsemblGenomes-Gn:BSU11840" /db_xref="EnsemblGenomes-Tr:CAB13041" /db_xref="GOA:O31628" /db_xref="InterPro:IPR000182" /db_xref="InterPro:IPR016181" /db_xref="PDB:1Q2Y" /db_xref="SubtiList:BG13159" /db_xref="UniProtKB/Swiss-Prot:O31628" /translation="MKAVIAKNEEQLKDAFYVREEVFVKEQNVPAEEEIDELENESEH IVVYDGEKPVGAGRWRMKDGYGKLERICVLKSHRSAGVGGIIMKALEKAAADGGASGF ILNAQTQAVPFYKKHGYRVLSEKEFLDAGIPHLQMMKD*" gene complement(1256436..1256858) /gene="yjcF" /locus_tag="BSU_11840" /old_locus_tag="BSU11840" CDS complement(1256862..1257377) /gene="yjcG" /locus_tag="BSU_11850" /old_locus_tag="BSU11850" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 12466548, 16511078, 17012785, 18473364, 25643072; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative RNA ligase or phosphoesterase" /protein_id="NP_389067.1" /db_xref="EnsemblGenomes-Gn:BSU11850" /db_xref="EnsemblGenomes-Tr:CAB13042" /db_xref="GOA:O31629" /db_xref="InterPro:IPR009097" /db_xref="InterPro:IPR022932" /db_xref="PDB:2D4G" /db_xref="SubtiList:BG13160" /db_xref="UniProtKB/Swiss-Prot:O31629" /translation="MKYGIVLFPSKKLQDLANSYRKRYDPSYSLIPPHLTLRASFECA EEKADQLVSHLRNIAKESHPLVLKMTKYSSFAPVNNVIYIKAEPTEELKTLNEKLYTG VLAGEQEYNFVPHVTVGQNLSDDEHSDVLGQLKMQEVSHEEIVDRFHLLYQLENGSWT VYETFLLGRGE*" gene complement(1256862..1257377) /gene="yjcG" /locus_tag="BSU_11850" /old_locus_tag="BSU11850" CDS complement(1257414..1258136) /gene="yjcH" /locus_tag="BSU_11860" /old_locus_tag="BSU11860" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 20941576; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative stress-related hydrolase" /protein_id="NP_389068.1" /db_xref="EnsemblGenomes-Gn:BSU11860" /db_xref="EnsemblGenomes-Tr:CAB13043" /db_xref="InterPro:IPR000801" /db_xref="InterPro:IPR029058" /db_xref="SubtiList:BG13161" /db_xref="UniProtKB/Swiss-Prot:O31630" /translation="MAPKNGTVQEKKFFSKELNEEMTLLVYLPSNYSPLYKYHVIIAQ DGHDYFRLGRIGRQVEELLSKREIDRSIIIGVPYKDVKERRNTYHPEGSKFSAYKRFI AHELVPFADDEYPTYQIGYGRTLIGDSLGATVSLMTALDYPNMFGNIIMQSPYVDKHV LEAVKQSDDIKHLSIYHQIGTKETDVHTTDGNILDFTEPNRELKQLLEKKLSDYDFEP FDGDHKWTYWQPLITPALKKML*" gene complement(1257414..1258136) /gene="yjcH" /locus_tag="BSU_11860" /old_locus_tag="BSU11860" misc_feature complement(1258175..1258194) /Source="Nicolas_upshift_promotors" /id="U963" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.999000999001" /psig=1 /xcortree=2938 /SigmaFactorBS="tttatttcaacacttttttcttcgtgtgccgaaccgtttaaa gagagaaatttctaataattCATGGTACAATAATTGAAAAtgcaagaaagtatagtga t" /listShort="yjcH, yjcG, yjcF" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(1258196) /Source="Nicolas_upshifts" /id="U963" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.999000999001" /psig=1 /xcortree=2938 /SigmaFactorBS="tttatttcaacacttttttcttcgtgtgccgaaccgtttaaa gagagaaatttctaataattCATGGTACAATAATTGAAAAtgcaagaaagtatagtga t" /listShort="yjcH, yjcG, yjcF" /GFF_Attribute="listLong" promotor_-35 1258245..1258252 /Source="Nicolas_upshift_promotors" /id="U964" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.986013986013986" /psig=1 /xcortree=2887 /SigmaFactorBS="tctctttaaacggttcggcacacgaagaaaaaagTGTTGAAA taaactgtgaattgCGCTAATATAAAACAATCAGaaaattgaaatcgatatttcttat c" /listShort="NA, metI, metC, S428" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1258267..1258286 /Source="Nicolas_upshift_promotors" /id="U964" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.986013986013986" /psig=1 /xcortree=2887 /SigmaFactorBS="tctctttaaacggttcggcacacgaagaaaaaagTGTTGAAA taaactgtgaattgCGCTAATATAAAACAATCAGaaaattgaaatcgatatttcttat c" /listShort="NA, metI, metC, S428" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1258271 /Source="Nicolas_upshifts" /id="U964" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.986013986013986" /psig=1 /xcortree=2887 /SigmaFactorBS="tctctttaaacggttcggcacacgaagaaaaaagTGTTGAAA taaactgtgaattgCGCTAATATAAAACAATCAGaaaattgaaatcgatatttcttat c" /listShort="NA, metI, metC, S428" /GFF_Attribute="listLong" misc_RNA 1258304..1258424 /gene="mswA" /locus_tag="BSU_misc_RNA_15" /product="S-adenosylmethionine riboswitch" /experiment="publication(s) with functional evidences, PMID:10094622, 12626738, 12910260, 17381305, 18039762" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10094622, 12626738, 12910260, 17381305, 18039762; Product type n: RNA" /function="16.3: Control" gene 1258304..1258424 /gene="mswA" /locus_tag="BSU_misc_RNA_15" downshifts 1258429 /Source="Nicolas_upshifts" /id="D651" /incds=0 /nref=8 /ntot=59 /MaxReadThrough="7.71668" /MaxDrop="5.0477" /score="31.1477774" /energy="-15.2" /TU="U964" /idTUdmin="U962" /TUdmin=2024 /isTUend="FALSE" CDS 1258492..1259613 /gene="metI" /locus_tag="BSU_11870" /old_locus_tag="BSU11870" /EC_number="2.5.1.49" /EC_number="2.5.1.48" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:10939241, 11832514, 22938038" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10939241, 11832514, 22938038; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="cystathionine gamma-synthase and O-acetylhomoserine thiolyase" /protein_id="NP_389069.1" /db_xref="EnsemblGenomes-Gn:BSU11870" /db_xref="EnsemblGenomes-Tr:CAB13044" /db_xref="GOA:O31631" /db_xref="InterPro:IPR000277" /db_xref="InterPro:IPR015421" /db_xref="InterPro:IPR015422" /db_xref="InterPro:IPR015424" /db_xref="SubtiList:BG13162" /db_xref="UniProtKB/Swiss-Prot:O31631" /translation="MSQHVETKLAQIGNRSDEVTGTVSAPIYLSTAYRHRGIGESTGF DYVRTKNPTRQLVEDAIANLENGARGLAFSSGMAAIQTIMALFKSGDELIVSSDLYGG TYRLFENEWKKYGLTFHYDDFSDEDCLRSKITPNTKAVFVETPTNPLMQEADIEHIAR ITKEHGLLLIVDNTFYTPVLQRPLELGADIVIHSATKYLGGHNDLLAGLVVVKDERLG EEMFQHQNAIGAVLPPFDSWLLMRGMKTLSLRMRQHQANAQELAAFLEEQEEISDVLY PGKGGMLSFRLQKEEWVNPFLKALKTICFAESLGGVESFITYPATQTHMDIPEEIRIA NGVCNRLLRFSVGIEHAEDLKEDLKQALCQVKEGAVSFE*" gene 1258492..1259613 /gene="metI" /locus_tag="BSU_11870" /old_locus_tag="BSU11870" CDS 1259606..1260778 /gene="metC" /locus_tag="BSU_11880" /old_locus_tag="BSU11880" /EC_number="4.4.1.8" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:10939241, 11832514, 11948165, 15760717" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10939241, 11832514, 11948165, 15760717; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="cystathionine beta-lyase" /protein_id="NP_389070.1" /db_xref="EnsemblGenomes-Gn:BSU11880" /db_xref="EnsemblGenomes-Tr:CAB13045" /db_xref="GOA:O31632" /db_xref="InterPro:IPR000277" /db_xref="InterPro:IPR015421" /db_xref="InterPro:IPR015422" /db_xref="InterPro:IPR015424" /db_xref="SubtiList:BG13163" /db_xref="UniProtKB/Swiss-Prot:O31632" /translation="MSKHNWTLETQLVHNPFKTDGGTGAVSVPIQHASTFHQSSFEEF GAYDYSRSGTPTRTALEETIAALEGGTRGFAFSSGMAAISTAFLLLSQGDHVLVTEDV YGGTFRMVTEVLTRFGIEHTFVDMTDRNEVARSIKPNTKVIYMETPSNPTLGITDIKA VVQLAKENGCLTFLDNTFMTPALQRPLDLGVDIVLHSATKFLSGHSDVLSGLAAVKDE ELGKQLYKLQNAFGAVLGVQDCWLVLRGLKTLQVRLEKASQTAQRLAEFFQKHPAVKR VYYPGLADHPGAETHKSQSTGAGAVLSFELESKEAVKKLVENVSLPVFAVSLGAVESI LSYPATMSHAAMPKEEREKRGITDGLLRLSVGVEHADDLEHDFEQALKEIAPVSVR*" gene 1259606..1260778 /gene="metC" /locus_tag="BSU_11880" /old_locus_tag="BSU11880" downshifts 1260761 /Source="Nicolas_upshifts" /id="D652" /incds=0 /nref=108 /ntot=205 /MaxReadThrough="4.73188" /MaxDrop="5.54268" /score="4.00424187" /energy="-9.2" /TU="U964" /idTUdmin="U964" /TUdmin="-1474" /isTUend="FALSE" misc_feature 1260795..1260813 /Source="Nicolas_upshift_promotors" /id="U965" /multdbtbs="-" /comp="M18" /sig="SigL" /pcomp="0.671328671328671" /psig="0.671328671328671" /xcortree=2911 /SigmaFactorBS="gctgaaagaaattgctccagtttcggttcgttaaaaaagaag ccggggatAGTCCGGCTTCTTTTATTAttgttcgtcatcaggattcagaatcgcgagg a" /listShort="S428" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 1260805 /Source="Nicolas_upshifts" /id="U965" /multdbtbs="-" /comp="M18" /sig="SigL" /pcomp="0.671328671328671" /psig="0.671328671328671" /xcortree=2911 /SigmaFactorBS="gctgaaagaaattgctccagtttcggttcgttaaaaaagaag ccggggatAGTCCGGCTTCTTTTATTAttgttcgtcatcaggattcagaatcgcgagg a" /listShort="S428" /GFF_Attribute="listLong" S_feature 1260806..1262335 /Source="Nicolas_S_feature" /locus_tag="new_1260806_1262335" /HighExp="MG 5, MG t5, MG 10, BMM, GM 25, MG 15, Glu, GM 15, GM 45, GM 10" /AntisenseName="yjcK" /AntisenseCor="0.123731990206979" /AntisenseRegPval="-1.4" /CDS_PredictionProba="NA" /TUshortSig="SigL, SigA" /TUshortPSig="0.671, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S428" CDS complement(1260811..1261356) /gene="yjcK" /locus_tag="BSU_11890" /old_locus_tag="BSU11890" /EC_number="2.3.1.267" /function="16.6: Maintain" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 2828880; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative ribosomal-protein-alanine N-acetyltransferase" /protein_id="NP_389071.1" /db_xref="EnsemblGenomes-Gn:BSU11890" /db_xref="EnsemblGenomes-Tr:CAB13046" /db_xref="GOA:O31633" /db_xref="InterPro:IPR000182" /db_xref="InterPro:IPR016181" /db_xref="SubtiList:BG13164" /db_xref="UniProtKB/Swiss-Prot:O31633" /translation="MLKGKTIYVRPLEVTDAEENLGLQSENRDFFEQFSMIRADDYYT VEGQRKRITEYQERLEKDEEYHFGIFTASDDRLIGTVSLFQIIRGALQTAFIGYFLDK AHNGKGIMTEAVRLVVDYAFHELKLHRIEAGVMPRNLGSMRVLEKAGFHKEGIARKNV KINGVWEDHQVLAILNPDDEQ*" gene complement(1260811..1261356) /gene="yjcK" /locus_tag="BSU_11890" /old_locus_tag="BSU11890" downshifts complement(1260832) /Source="Nicolas_upshifts" /id="D653" /incds=0 /nref=14 /ntot=127 /MaxReadThrough="0.4032" /MaxDrop="4.23858" /score="-7.12102596" /energy="-7.3" /TU="NA" /idTUdmin="U966" /TUdmin="-17" /isTUend="TRUE" CDS complement(1261426..1262616) /gene="yjcL" /locus_tag="BSU_11900" /old_locus_tag="BSU11900" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative integral inner membrane protein; possibly aquaporin-related" /protein_id="NP_389072.1" /db_xref="EnsemblGenomes-Gn:BSU11900" /db_xref="EnsemblGenomes-Tr:CAB13047" /db_xref="GOA:O31634" /db_xref="InterPro:IPR008537" /db_xref="SubtiList:BG13165" /db_xref="UniProtKB/Swiss-Prot:O31634" /translation="MHSLISSDDVWVLWGFIAVWAAVSIGLEQRFKWASAVSGAIIAL AGAMVFTNVGVLPVESPVYDTVWSYVVPLAIPLLLFQINVRQIFKESRRLLFIFLISS VGTVLGSILAFFLLKQHIPYLDKIGGMISASYIGGGVNFAAMAAKFETPGEYVSATVV ADNFMMALLFFILISIPALKWFQRHYAMPFEEKVKADGNSGNSAESYWKRKDISLKDI AFNAGAAFALVAVSMKVSGYFKSIFSHPLLTGTLGDQYLVLTSLTVLIIFLFPRFFER LNGSQELGTFLIYLFFVVIGIPADLRLIVTNAPLILLFVFIIAISNLAVSLAAGKLFR VRLEEILLAVNATVGGPTTAAAMAIAKGWRELVAPIMLVGTLGYLIGNYVGTFMGNWF SSFL*" gene complement(1261426..1262616) /gene="yjcL" /locus_tag="BSU_11900" /old_locus_tag="BSU11900" promotor_-10 complement(1262642..1262661) /Source="Nicolas_upshift_promotors" /id="U966" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.448551448551449" /psig=1 /xcortree=2871 /SigmaFactorBS="ttttttagaaaaactttttttggACTTGCTGttccgttcccc ggcTATTATAATATGTCTTAATTttctaacaatagaggtgatggggttttgcattctt t" /listShort="yjcL, yjcK" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1262646) /Source="Nicolas_upshifts" /id="U966" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.448551448551449" /psig=1 /xcortree=2871 /SigmaFactorBS="ttttttagaaaaactttttttggACTTGCTGttccgttcccc ggcTATTATAATATGTCTTAATTttctaacaatagaggtgatggggttttgcattctt t" /listShort="yjcL, yjcK" /GFF_Attribute="listLong" promotor_-35 complement(1262676..1262683) /Source="Nicolas_upshift_promotors" /id="U966" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.448551448551449" /psig=1 /xcortree=2871 /SigmaFactorBS="ttttttagaaaaactttttttggACTTGCTGttccgttcccc ggcTATTATAATATGTCTTAATTttctaacaatagaggtgatggggttttgcattctt t" /listShort="yjcL, yjcK" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1262710..1262717 /Source="Nicolas_upshift_promotors" /id="U967" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.85914085914086" /psig=1 /xcortree=2414 /SigmaFactorBS="agccggggaacggaacagcaagtccaaaaaaagtttttctaa aaaagcaGTTGACGAatagaaggtaaggTTATATAATAGAACTTGTCAgaaagataac a" /listShort="trnSL-Val2, S430" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 1262721 /Source="Nicolas_upshifts" /id="U967" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.85914085914086" /psig=1 /xcortree=2414 /SigmaFactorBS="agccggggaacggaacagcaagtccaaaaaaagtttttctaa aaaagcaGTTGACGAatagaaggtaaggTTATATAATAGAACTTGTCAgaaagataac a" /listShort="trnSL-Val2, S430" /GFF_Attribute="listLong" promotor_-10 1262731..1262750 /Source="Nicolas_upshift_promotors" /id="U967" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.85914085914086" /psig=1 /xcortree=2414 /SigmaFactorBS="agccggggaacggaacagcaagtccaaaaaaagtttttctaa aaaagcaGTTGACGAatagaaggtaaggTTATATAATAGAACTTGTCAgaaagataac a" /listShort="trnSL-Val2, S430" /GFF_Attribute="listLong" /label="promotor_-10" tRNA 1262789..1262861 /gene="trnSL-Val2" /locus_tag="BSU_tRNA_83" /product="tRNA-Val" /inference="profile:tRNAscan:1.23" /note="valine tRNA (GAC); Evidence 2a: Function from experimental evidences in other organisms; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene 1262789..1262861 /gene="trnSL-Val2" /locus_tag="BSU_tRNA_83" promotor_-10 complement(1262803..1262820) /Source="Nicolas_upshift_promotors" /id="U968" /multdbtbs="-" /comp="M20" /sig="Sig-" /pcomp="0.926073926073926" /psig="0.007992007992008" /xcortree=394 /SigmaFactorBS="gcaagggtttaagctatgattccgactgggCTCGAACcagcg acctctaccctgtcaAGGTAGCGCTCTCCCAGCtgagctacggaatcatgatatgtat g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1262817) /Source="Nicolas_upshifts" /id="U968" /multdbtbs="-" /comp="M20" /sig="Sig-" /pcomp="0.926073926073926" /psig="0.007992007992008" /xcortree=394 /SigmaFactorBS="gcaagggtttaagctatgattccgactgggCTCGAACcagcg acctctaccctgtcaAGGTAGCGCTCTCCCAGCtgagctacggaatcatgatatgtat g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(1262841..1262847) /Source="Nicolas_upshift_promotors" /id="U968" /multdbtbs="-" /comp="M20" /sig="Sig-" /pcomp="0.926073926073926" /psig="0.007992007992008" /xcortree=394 /SigmaFactorBS="gcaagggtttaagctatgattccgactgggCTCGAACcagcg acctctaccctgtcaAGGTAGCGCTCTCCCAGCtgagctacggaatcatgatatgtat g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 1262851 /Source="Nicolas_upshifts" /id="D654" /incds=0 /nref=17 /ntot=80 /MaxReadThrough="4.64061" /MaxDrop="5.10012" /score="20.8247903" /energy="-9.1" /TU="U967" /idTUdmin="U965" /TUdmin=550 /isTUend="FALSE" S_feature complement(1262876..1263611) /Source="Nicolas_S_feature" /locus_tag="new_1262876_1263611_c" /HighExp="M9-stat, Lbstat, M0t90, Pyr, T0.30H, M40t90, C30, S1, LPhT, T1.30H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S429" S_feature 1262896..1264544 /Source="Nicolas_S_feature" /locus_tag="new_1262896_1264544" /HighExp="Cold, C30, G135, G180, G150, Oxctl, Fru, HPh, Glu, UNK1" /AntisenseName="yjcM" /AntisenseCor="0.46809452811910301" /AntisenseRegPval="-15.3" /CDS_PredictionProba="0.27514300000000003" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S430" downshifts complement(1262905) /Source="Nicolas_upshifts" /id="D655" /incds=0 /nref=29 /ntot=192 /MaxReadThrough="1.23936" /MaxDrop="3.57085" /score="-4.98447688" /energy="-7.9" /TU="NA" /idTUdmin="U970" /TUdmin=0 /isTUend="TRUE" S_feature complement(1263613..1263701) /Source="Nicolas_S_feature" /locus_tag="new_1263613_1263701_c" /HighExp="aero, HPh, M0t45, SMM, dia0, GM 150, Mal, M/G, Mt0, LPh" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S431" downshifts complement(1263656) /Source="Nicolas_upshifts" /id="D656" /incds=0 /nref=34 /ntot=148 /MaxReadThrough="4.13737" /MaxDrop="4.5557" /score="11.73443" /energy="-14.2" /TU="U970" /idTUdmin="U970" /TUdmin="-751" /isTUend="FALSE" CDS complement(1263702..1264931) /gene="yjcM" /locus_tag="BSU_11910" /old_locus_tag="BSU11910" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 20011599" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein; phage island" /protein_id="NP_389073.1" /db_xref="EnsemblGenomes-Gn:BSU11910" /db_xref="EnsemblGenomes-Tr:CAB13048" /db_xref="InterPro:IPR024301" /db_xref="SubtiList:BG13166" /db_xref="UniProtKB/Swiss-Prot:O31635" /translation="MKKELLASLVLCLSLSPLVSTNEVFAATTNKETKENVSITNEIG YEKVKDMLEQQKYDFEHNTPLAHPKESKLTDSDEGVLLYSALSKVDKQKFHEFTYDID DVKTSEKNNKLIVEAYITRNFVFGVEKVTTSLGDNIKLEIPKTTSNKQSSQSTNTSNL SFSQVKNSSNQLNVIPLSNSSKQLNVTQLNNSSSTLQYENDEEYSSDVKLDEFLKKYK QEVKNDDKEEVKSEDKPVSMNFNAANSNQLTVTATSVKGYSGYAAMKYAEKYALKPNK NYKYYKDKDCTNFVSQALRAGRMPYFKEWKPYTDAWVNAGAFRSYILKAGGIKMKTVS DTYSNVKLGDVYHYDYHNKIGLRYADGWMDHTAIVTSRANMKLYVSYHSTNRLNVPRE YVTSKEGGKRYVSSIRN*" gene complement(1263702..1264931) /gene="yjcM" /locus_tag="BSU_11910" /old_locus_tag="BSU11910" downshifts complement(1263824) /Source="Nicolas_upshifts" /id="D657" /incds=1 /nref=4 /ntot=143 /MaxReadThrough="5.58558" /MaxDrop="3.45178" /score="11.73443" /energy="-14.2" /TU="U970" /idTUdmin="U970" /TUdmin="-919" /isTUend="FALSE" downshifts 1264501 /Source="Nicolas_upshifts" /id="D658" /incds=1 /nref=1 /ntot=48 /MaxReadThrough="3.19343" /MaxDrop="1.98614" /score="26.2462772" /energy="-24.7" /TU="NA" /idTUdmin="U967" /TUdmin=0 /isTUend="TRUE" S_feature complement(1264932..1265017) /Source="Nicolas_S_feature" /locus_tag="new_1264932_1265017_c" /HighExp="aero, SMM, T-3.40H, MG 150, Lbexp, SMMPr, GM 90, C90, nit, HPh" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S432" promotor_-35 1264972..1264979 /Source="Nicolas_upshift_promotors" /id="U969" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.97902097902098" /psig="0.998001998001998" /xcortree=2298 /SigmaFactorBS="aaatctaaatataagtaatatttatCATTTACAccaattgaa atatgGCATAAAATACATGTAATAAtataacataaaaataaatacataaaaaggtatc g" /listShort="yjcN, S433, yjzF, yjzG, yjcO, S434, yjcP, yjcQ" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1264994..1265013 /Source="Nicolas_upshift_promotors" /id="U969" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.97902097902098" /psig="0.998001998001998" /xcortree=2298 /SigmaFactorBS="aaatctaaatataagtaatatttatCATTTACAccaattgaa atatgGCATAAAATACATGTAATAAtataacataaaaataaatacataaaaaggtatc g" /listShort="yjcN, S433, yjzF, yjzG, yjcO, S434, yjcP, yjcQ" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-10 complement(1265003..1265022) /Source="Nicolas_upshift_promotors" /id="U970" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.320679320679321" /psig="0.999000999001" /xcortree=2299 /SigmaFactorBS="gtataattttagttttctttttcattttttcctccgatacCT TTTTAtgtatttattttTATGTTATATTATTACATGTattttatgccatatttcaatt g" /listShort="S432, yjcM, S431, S429" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1265007 /Source="Nicolas_upshifts" /id="U969" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.97902097902098" /psig="0.998001998001998" /xcortree=2298 /SigmaFactorBS="aaatctaaatataagtaatatttatCATTTACAccaattgaa atatgGCATAAAATACATGTAATAAtataacataaaaataaatacataaaaaggtatc g" /listShort="yjcN, S433, yjzF, yjzG, yjcO, S434, yjcP, yjcQ" /GFF_Attribute="listLong" upshifts complement(1265021) /Source="Nicolas_upshifts" /id="U970" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.320679320679321" /psig="0.999000999001" /xcortree=2299 /SigmaFactorBS="gtataattttagttttctttttcattttttcctccgatacCT TTTTAtgtatttattttTATGTTATATTATTACATGTattttatgccatatttcaatt g" /listShort="S432, yjcM, S431, S429" /GFF_Attribute="listLong" promotor_-35 complement(1265035..1265041) /Source="Nicolas_upshift_promotors" /id="U970" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.320679320679321" /psig="0.999000999001" /xcortree=2299 /SigmaFactorBS="gtataattttagttttctttttcattttttcctccgatacCT TTTTAtgtatttattttTATGTTATATTATTACATGTattttatgccatatttcaatt g" /listShort="S432, yjcM, S431, S429" /GFF_Attribute="listLong" /label="promotor_-35" CDS 1265057..1265377 /gene="yjcN" /locus_tag="BSU_11920" /old_locus_tag="BSU11920" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein; phage island" /protein_id="NP_389074.1" /db_xref="EnsemblGenomes-Gn:BSU11920" /db_xref="EnsemblGenomes-Tr:CAB13049" /db_xref="SubtiList:BG13167" /db_xref="UniProtKB/Swiss-Prot:O31636" /translation="MKKKTKIILSLLAALIVILIVLPVLSPVVFTASSEKGAIRHEIY KRGYPYQSYFAVLQKREGDNESGNLYYVNWLDWKDETGQTPHLCYSKKSSDGEYEVSC GTGP*" gene 1265057..1265377 /gene="yjcN" /locus_tag="BSU_11920" /old_locus_tag="BSU11920" downshifts 1265387 /Source="Nicolas_upshifts" /id="D659" /incds=0 /nref=57 /ntot=233 /MaxReadThrough="3.73892" /MaxDrop="4.41989" /score="26.2462772" /energy="-24.7" /TU="U969" /idTUdmin="U967" /TUdmin=886 /isTUend="FALSE" S_feature 1265432..1265529 /Source="Nicolas_S_feature" /locus_tag="new_1265432_1265529" /HighExp="LoTm, B60, Cold, B36, T3.30H, T3.0H, T4.0H, T2.0H, Sw, M9-stat" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.998" /TUlongSig="NA" /TUlongPSig="NA" /label="S433" CDS 1265530..1265661 /gene="yjzF" /locus_tag="BSU_11928" /old_locus_tag="BSU11928" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="YP_003097707.1" /db_xref="EnsemblGenomes-Gn:BSU11928" /db_xref="EnsemblGenomes-Tr:CAX52597" /db_xref="UniProtKB/Swiss-Prot:C0H3Z0" /translation="MKQSKKKPSQKQHERLDRFWQQMMNTNMQTLRRGKGGAYKRRK* " gene 1265530..1265661 /gene="yjzF" /locus_tag="BSU_11928" /old_locus_tag="BSU11928" CDS 1265677..1265850 /gene="yjzG" /locus_tag="BSU_11929" /old_locus_tag="BSU11929" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_003097708.1" /db_xref="EnsemblGenomes-Gn:BSU11929" /db_xref="EnsemblGenomes-Tr:CAX52598" /db_xref="UniProtKB/Swiss-Prot:C0H3Z1" /translation="MMKNGFAYKNGKLVNIFCGKEELYNELKAFLVKTFSINVKEVSR PSIYRRTKSKQLE*" gene 1265677..1265850 /gene="yjzG" /locus_tag="BSU_11929" /old_locus_tag="BSU11929" CDS 1265887..1266348 /gene="yjcO" /locus_tag="BSU_11930" /old_locus_tag="BSU11930" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative DNA binding protein; phage island" /protein_id="NP_389075.1" /db_xref="EnsemblGenomes-Gn:BSU11930" /db_xref="EnsemblGenomes-Tr:CAB13050" /db_xref="GOA:O31637" /db_xref="InterPro:IPR013324" /db_xref="SubtiList:BG13168" /db_xref="UniProtKB/Swiss-Prot:O31637" /translation="MTDQMIAWEIEEWIRDYKFMLREIKRLNRVLNKVDFISTKLTAT YGEEAGMPRGSAGVSQAELRQMDRRERRLHKYESIVHYLDNAMEHIEEEKHRIVYDCM MEGMSYTAIANHLDCSRDTIRKIKTAIIGNIVNKVKEANFLQYLNSFKSAV*" gene 1265887..1266348 /gene="yjcO" /locus_tag="BSU_11930" /old_locus_tag="BSU11930" promotor_-35 1266319..1266326 /Source="Nicolas_upshift_promotors" /id="U971" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.992007992007992" /psig="0.997002997002997" /xcortree=2045 /SigmaFactorBS="aataaagtcaaagaagccaactttctgcaaTATTTGAAttcg tttaaatcggCGGTGTAAAATGGGGGGCAGgatcggcgcggcggattattcctgcgtc a" /listShort="S434" /listLong="yjcP, yjcQ" /label="promotor_-35" promotor_-10 1266341..1266360 /Source="Nicolas_upshift_promotors" /id="U971" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.992007992007992" /psig="0.997002997002997" /xcortree=2045 /SigmaFactorBS="aataaagtcaaagaagccaactttctgcaaTATTTGAAttcg tttaaatcggCGGTGTAAAATGGGGGGCAGgatcggcgcggcggattattcctgcgtc a" /listShort="S434" /listLong="yjcP, yjcQ" /label="promotor_-10" S_feature 1266349..1266589 /Source="Nicolas_S_feature" /locus_tag="new_1266349_1266589" /HighExp="LoTm, B60, Cold, B36, Diami, S8, dia15, C30, dia5, LPhT" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.12525800000000001" /TUshortSig="SigA, SigA" /TUshortPSig="0.997, 0.998" /TUlongSig="NA" /TUlongPSig="NA" /label="S434" upshifts 1266349 /Source="Nicolas_upshifts" /id="U971" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.992007992007992" /psig="0.997002997002997" /xcortree=2045 /SigmaFactorBS="aataaagtcaaagaagccaactttctgcaaTATTTGAAttcg tttaaatcggCGGTGTAAAATGGGGGGCAGgatcggcgcggcggattattcctgcgtc a" /listShort="S434" /listLong="yjcP, yjcQ" promotor_-35 1266562..1266569 /Source="Nicolas_upshift_promotors" /id="U972" /multdbtbs="SigD" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2836 /SigmaFactorBS="caacagattcgttcgacaaattttgcaaattGTTAATCGata acttttcattCCCGATATTAAAAATGGGAgtgaattgtaaaatgaaaaaacagaaaaa t" /listShort="yjcP, yjcQ" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1266583..1266601 /Source="Nicolas_upshift_promotors" /id="U972" /multdbtbs="SigD" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2836 /SigmaFactorBS="caacagattcgttcgacaaattttgcaaattGTTAATCGata acttttcattCCCGATATTAAAAATGGGAgtgaattgtaaaatgaaaaaacagaaaaa t" /listShort="yjcP, yjcQ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1266591 /Source="Nicolas_upshifts" /id="U972" /multdbtbs="SigD" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2836 /SigmaFactorBS="caacagattcgttcgacaaattttgcaaattGTTAATCGata acttttcattCCCGATATTAAAAATGGGAgtgaattgtaaaatgaaaaaacagaaaaa t" /listShort="yjcP, yjcQ" /GFF_Attribute="listLong" CDS 1266614..1267117 /gene="yjcP" /locus_tag="BSU_11940" /old_locus_tag="BSU11940" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 15033535" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein: phage island" /protein_id="NP_389076.1" /db_xref="EnsemblGenomes-Gn:BSU11940" /db_xref="EnsemblGenomes-Tr:CAB13051" /db_xref="GOA:O31638" /db_xref="SubtiList:BG13169" /db_xref="UniProtKB/Swiss-Prot:O31638" /translation="MKKQKNNKKKNIEKRNIEKRNIEEKNNEDLEELENAIYTYHKKE LLAFFLEKTRIGHDKEEYKRFQSLLYKLDIECLEFAISRFSHIDIIHDHSKYVPAFIP LFAAYLTMFFNFYEKHWGALSFAAGTIAAIVWIIAVERKHRNQAISIMKIFEQVKERK VKDRSKD*" gene 1266614..1267117 /gene="yjcP" /locus_tag="BSU_11940" /old_locus_tag="BSU11940" CDS 1267129..1267413 /gene="yjcQ" /locus_tag="BSU_11950" /old_locus_tag="BSU11950" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 15033535" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein; phage island" /protein_id="NP_389077.1" /db_xref="EnsemblGenomes-Gn:BSU11950" /db_xref="EnsemblGenomes-Tr:CAB13052" /db_xref="InterPro:IPR018597" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="PDB:2HGC" /db_xref="SubtiList:BG13170" /db_xref="UniProtKB/Swiss-Prot:O31639" /translation="MNKDKLRYAILKEIFEGNTPLSENDIGVTEDQFDDAVNFLKREG YIIGVHYSDDRPHLYKLGPELTEKGENYLKENGTWSKAYKTIKEIKDWIK*" gene 1267129..1267413 /gene="yjcQ" /locus_tag="BSU_11950" /old_locus_tag="BSU11950" downshifts 1267383 /Source="Nicolas_upshifts" /id="D660" /incds=0 /nref=215 /ntot=271 /MaxReadThrough="1.63272" /MaxDrop="7.26386" /score="22.0381158" /energy="-7.2" /TU="NA" /idTUdmin="U969" /TUdmin=0 /isTUend="TRUE" upshifts complement(1267415) /Source="Nicolas_upshifts" /id="U973" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.828171828171828" /psig="0.107892107892108" /xcortree=80 /SigmaFactorBS="tcctgagacttaccggaagcagtttacagggaacaaaaaaag caccCCGCaggatgctcttattatttaatccaatctttaatctctttaatggtcttat a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" misc_feature complement(1267426..1267429) /Source="Nicolas_upshift_promotors" /id="U973" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.828171828171828" /psig="0.107892107892108" /xcortree=80 /SigmaFactorBS="tcctgagacttaccggaagcagtttacagggaacaaaaaaag caccCCGCaggatgctcttattatttaatccaatctttaatctctttaatggtcttat a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" CDS 1267574..1268101 /gene="yjcR" /locus_tag="BSU_11960" /old_locus_tag="BSU11960" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 7489895, 7704261; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative phage-related nucleic acid binding terminase small subunit; phage island" /protein_id="NP_389078.1" /db_xref="EnsemblGenomes-Gn:BSU11960" /db_xref="EnsemblGenomes-Tr:CAB13053" /db_xref="GOA:O31640" /db_xref="InterPro:IPR009057" /db_xref="InterPro:IPR010332" /db_xref="SubtiList:BG13171" /db_xref="UniProtKB/Swiss-Prot:O31640" /translation="MAEKHIQAYKDYVKGMKYKDLAEKYGVSVNTIKSWKQRHGWERK KGAPIEKSVHTKKGGQPGNKNALGNNGGAPQKNQNAVTHGFFSKFLPEETLEIMEEIQ ERSPADMIWDQIQIQYAAILRAQKIMFVSDKEEMIKELKKKRSLISEVSEIEDGLVIS FSTWFRYRLYSETNT*" gene 1267574..1268101 /gene="yjcR" /locus_tag="BSU_11960" /old_locus_tag="BSU11960" promotor_-35 1268248..1268253 /Source="Nicolas_upshift_promotors" /id="U974" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.748251748251748" /psig="0.992007992007992" /xcortree=2218 /SigmaFactorBS="tacagcgattgattaactcgagcaatcaatgtcgcagttATA TTTatttttcaagaaAATGTTATAATGAAAAGCCAtaaaatgatgggagggggaattt c" /listShort="yjcS, S435, yjdA, S436" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1268266..1268285 /Source="Nicolas_upshift_promotors" /id="U974" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.748251748251748" /psig="0.992007992007992" /xcortree=2218 /SigmaFactorBS="tacagcgattgattaactcgagcaatcaatgtcgcagttATA TTTatttttcaagaaAATGTTATAATGAAAAGCCAtaaaatgatgggagggggaattt c" /listShort="yjcS, S435, yjdA, S436" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1268269 /Source="Nicolas_upshifts" /id="U974" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.748251748251748" /psig="0.992007992007992" /xcortree=2218 /SigmaFactorBS="tacagcgattgattaactcgagcaatcaatgtcgcagttATA TTTatttttcaagaaAATGTTATAATGAAAAGCCAtaaaatgatgggagggggaattt c" /listShort="yjcS, S435, yjdA, S436" /GFF_Attribute="listLong" CDS 1268275..1268592 /gene="yjcS" /locus_tag="BSU_11970" /old_locus_tag="BSU11970" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein; phage island" /protein_id="NP_389079.1" /db_xref="EnsemblGenomes-Gn:BSU11970" /db_xref="EnsemblGenomes-Tr:CAB13054" /db_xref="GOA:O31641" /db_xref="InterPro:IPR007138" /db_xref="InterPro:IPR011008" /db_xref="PDB:1Q8B" /db_xref="SubtiList:BG13172" /db_xref="UniProtKB/Swiss-Prot:O31641" /translation="MKSHKMMGGGISMHYITACLKIISDKDLNEIMKEFKKLEEETNK EEGCITFHAYPLEPSERKIMLWEIWENEEAVKIHFTKKHTIDVQKQELTEVEWLMKSN VND*" gene 1268275..1268592 /gene="yjcS" /locus_tag="BSU_11970" /old_locus_tag="BSU11970" S_feature 1268593..1268828 /Source="Nicolas_S_feature" /locus_tag="new_1268593_1268828" /HighExp="dia5, H2O2, dia15, dia0, Lbexp, Lbtran, C90, Oxctl, S1, aero" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.992" /TUlongSig="NA" /TUlongPSig="NA" /label="S435" CDS 1268829..1269584 /gene="yjdA" /locus_tag="BSU_11980" /old_locus_tag="BSU11980" /EC_number="1.1.1.-" /function="16.2: Construct biomass (Anabolism)" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 2243795; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative acyl-carrier protein oxidoreductase; phage island" /protein_id="NP_389080.1" /db_xref="EnsemblGenomes-Gn:BSU11980" /db_xref="EnsemblGenomes-Tr:CAB13055" /db_xref="GOA:O31642" /db_xref="InterPro:IPR002347" /db_xref="InterPro:IPR020904" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG13173" /db_xref="UniProtKB/Swiss-Prot:O31642" /translation="MSHSQEKIALITGASSQGDIGTAICRKLASQGIHIFFTHWNSDT AWIEEFQQEILRMGVRCEAMKIDLSDAHAAFTIHEKISDKLGYPSILINNAAHSASDN YVSLDAKSLDEHYAVNMRSNFLLCVEFARRFKKSNLISGRIINMTSGQDLGPLPGELA YAATKGAISAFTRSLSQELAPLGITVNAVNPGPTDSTWMTDEIRNFLSPKFPMGRIGT PDDAARMIAFLASDEAEWITGQIIHSEGGFIRG*" gene 1268829..1269584 /gene="yjdA" /locus_tag="BSU_11980" /old_locus_tag="BSU11980" S_feature 1269585..1269672 /Source="Nicolas_S_feature" /locus_tag="new_1269585_1269672" /HighExp="C90, S1, dia0, dia5, Mt0, Lbexp, Gly, H2O2, Oxctl, Lbtran" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.992" /TUlongSig="NA" /TUlongPSig="NA" /label="S436" downshifts 1269629 /Source="Nicolas_upshifts" /id="D661" /incds=0 /nref=89 /ntot=238 /MaxReadThrough="2.66489" /MaxDrop="5.39812" /score="-0.84766737" /energy="-14.2" /TU="NA" /idTUdmin="U974" /TUdmin="-20" /isTUend="TRUE" S_feature complement(1269672..1269732) /Source="Nicolas_S_feature" /locus_tag="new_1269672_1269732_c" /HighExp="Lbstat, BI, BT, nit, S2, ferm, B60, B36, M0t90, S3" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="NA" /TUshortPSig="NA" /TUlongSig="NA" /TUlongPSig="NA" /label="S437" downshifts complement(1269703) /Source="Nicolas_upshifts" /id="D662" /incds=0 /nref=80 /ntot=134 /MaxReadThrough="1.9707" /MaxDrop="7.43843" /score="-5.56180712" /energy="-14.2" /TU="NA" /idTUdmin="U975" /TUdmin=0 /isTUend="TRUE" CDS complement(1269733..1270080) /gene="yjdB" /locus_tag="BSU_11990" /old_locus_tag="BSU11990" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 16291680; Product type h: extrachromosomal origin" /codon_start=1 /transl_table=11 /product="putative exported protein; phage island" /protein_id="NP_389081.1" /db_xref="EnsemblGenomes-Gn:BSU11990" /db_xref="EnsemblGenomes-Tr:CAB13056" /db_xref="InterPro:IPR003343" /db_xref="InterPro:IPR008964" /db_xref="SubtiList:BG13174" /db_xref="UniProtKB/Swiss-Prot:O31643" /translation="MNFKKTVVSALSISALALSVSGVASAHEINSTPTEVKNISISPT HVIKIQDYNLPLKVGETYSVKNNSATRYWTDNQKVAEVDQNGLVTAKSKGKATITLFK GTAVFGKVYVTVY*" gene complement(1269733..1270080) /gene="yjdB" /locus_tag="BSU_11990" /old_locus_tag="BSU11990" promotor_-10 complement(1270112..1270130) /Source="Nicolas_upshift_promotors" /id="U975" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=507 /SigmaFactorBS="tcaattgatcgttcacatattattaacatttatttaCAAGGA AAAtaattactttTATTGAATTGTTATAGTGCaagacaaaaaactttaaaggagtgtt t" /listShort="yjdB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1270125) /Source="Nicolas_upshifts" /id="U975" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=507 /SigmaFactorBS="tcaattgatcgttcacatattattaacatttatttaCAAGGA AAAtaattactttTATTGAATTGTTATAGTGCaagacaaaaaactttaaaggagtgtt t" /listShort="yjdB" /GFF_Attribute="listLong" S_feature complement(1270127..1270583) /Source="Nicolas_S_feature" /locus_tag="new_1270127_1270583_c" /HighExp="T1.30H, T2.0H, T2.30H, T3.0H, M9-stat, T1.0H, Lbstat, T3.30H, M0t90, Lbtran" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.983" /TUlongSig="NA" /TUlongPSig="NA" /label="S438" promotor_-35 complement(1270141..1270149) /Source="Nicolas_upshift_promotors" /id="U975" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=507 /SigmaFactorBS="tcaattgatcgttcacatattattaacatttatttaCAAGGA AAAtaattactttTATTGAATTGTTATAGTGCaagacaaaaaactttaaaggagtgtt t" /listShort="yjdB" /GFF_Attribute="listLong" /label="promotor_-35" misc_feature 1270543..1270561 /Source="Nicolas_upshift_promotors" /id="U976" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.33966033966034" /psig="0.99100899100899" /xcortree=1564 /SigmaFactorBS="tttttccggaagcttcggtaaaaaacgaaacttttgtctcta tgatttTGTTTTATAATGTAAACGGtttcttatatagtatacttatactatcaatttg c" /listShort="manR" /listLong="manP, manA, S439, S440, yjdF, yjdI" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 1270555 /Source="Nicolas_upshifts" /id="U976" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.33966033966034" /psig="0.99100899100899" /xcortree=1564 /SigmaFactorBS="tttttccggaagcttcggtaaaaaacgaaacttttgtctcta tgatttTGTTTTATAATGTAAACGGtttcttatatagtatacttatactatcaatttg c" /listShort="manR" /listLong="manP, manA, S439, S440, yjdF, yjdI" promotor_-10 complement(1270561..1270580) /Source="Nicolas_upshift_promotors" /id="U977" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.572427572427572" /psig="0.983016983016983" /xcortree=327 /SigmaFactorBS="ttatgtattccatctgtttttctatccttcctgtcagtatct ACTTGAGCaaattgatagtatAAGTATACTATATAAGAAACcgtttacattataaaac a" /listShort="S438, yjdB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1270583) /Source="Nicolas_upshifts" /id="U977" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.572427572427572" /psig="0.983016983016983" /xcortree=327 /SigmaFactorBS="ttatgtattccatctgtttttctatccttcctgtcagtatct ACTTGAGCaaattgatagtatAAGTATACTATATAAGAAACcgtttacattataaaac a" /listShort="S438, yjdB" /GFF_Attribute="listLong" promotor_-35 complement(1270594..1270601) /Source="Nicolas_upshift_promotors" /id="U977" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.572427572427572" /psig="0.983016983016983" /xcortree=327 /SigmaFactorBS="ttatgtattccatctgtttttctatccttcctgtcagtatct ACTTGAGCaaattgatagtatAAGTATACTATATAAGAAACcgtttacattataaaac a" /listShort="S438, yjdB" /GFF_Attribute="listLong" /label="promotor_-35" CDS 1270631..1272577 /gene="manR" /locus_tag="BSU_12000" /old_locus_tag="BSU12000" /function="16.1: Circulate" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:10438772, 10960106, 23551403" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10438772, 10960106, 23551403; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional DNA-binding activator" /protein_id="NP_389082.2" /db_xref="EnsemblGenomes-Gn:BSU12000" /db_xref="EnsemblGenomes-Tr:CAB13057" /db_xref="GOA:O31644" /db_xref="InterPro:IPR002178" /db_xref="InterPro:IPR007737" /db_xref="InterPro:IPR011608" /db_xref="InterPro:IPR013011" /db_xref="InterPro:IPR013196" /db_xref="InterPro:IPR016152" /db_xref="InterPro:IPR036095" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036634" /db_xref="SubtiList:BG13175" /db_xref="UniProtKB/Swiss-Prot:O31644" /translation="MEYINTRQKEILYLLLSEPDDYLVVQDFADRVQCSEKTIRNDLK VIEDYLNEHSHAQLIRKPGLGVYLHIEEQERTWLSQQLHTEHFSSRQRSDKERMLHIA YDLLMNPKPVSAKDIAARHFVNRSSIKKDLYAVEEWLKRFDLTLVSRQRLGLKVEGNE RNKRKALARISDLIHNTAFTSQFIKSKFLHYEVDFVTKEIKSLQKKHSLYFTDETFES LLLHTLLMVRRIKMKQPISLSPKEMAAVKKKKEYQWTFACLQRLEPVFAIRFPEEEAV YLTLHILGGKVRYPLQTEENLENAVLPKVVGHLINRVSELKMMDFHKDQDLINGLNIH LNTVLQRLSYDLSVANPMLNDIKKMYPYLFHLIIDVLEDINQTFDLHIPEEEAAYLTL HFQAAIERMQGSSETHKKAVIVCHMGIGMSQLLRTKIERKYHQIAVMACIAKADLKDY IKKHEDIDLVISTIALENITVPHIVVSPLLEPGEEKKLSAFIRQLGESHRQKQKTFQM LNNTTPFLVFLQQEAEHRYKLIEQLATALFEKGYVDKDYAVHAVMREKMSATNIGSGI AIPHANAKFIKQSAIAIATLKEPLEWGNEKVSLVFMLAVKHEDQTMTKQLFSELSYLS EQPAFVQKLTKETNVMTFLSHLDY*" gene 1270631..1272577 /gene="manR" /locus_tag="BSU_12000" /old_locus_tag="BSU12000" downshifts 1272553 /Source="Nicolas_upshifts" /id="D663" /incds=0 /nref=3 /ntot=35 /MaxReadThrough="4.64475" /MaxDrop="3.79938" /score="28.4199725" /energy="-9.1" /TU="U976" /idTUdmin="U976" /TUdmin="-110" /isTUend="FALSE" promotor_-35 1272653..1272656 /Source="Nicolas_upshift_promotors" /id="U978" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.424575424575425" /psig="0.936063936063936" /xcortree=1565 /SigmaFactorBS="tttattaccggaacctatggtaaaaaaagcGATTttaatgag ctgatttCGGTATACAGTTGAGACAAGatcttattattcacactttaaaggaggtttc c" /listShort="manP, manA, S439, S440, yjdF, yjdI" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1272672..1272691 /Source="Nicolas_upshift_promotors" /id="U978" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.424575424575425" /psig="0.936063936063936" /xcortree=1565 /SigmaFactorBS="tttattaccggaacctatggtaaaaaaagcGATTttaatgag ctgatttCGGTATACAGTTGAGACAAGatcttattattcacactttaaaggaggtttc c" /listShort="manP, manA, S439, S440, yjdF, yjdI" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1272683 /Source="Nicolas_upshifts" /id="U978" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.424575424575425" /psig="0.936063936063936" /xcortree=1565 /SigmaFactorBS="tttattaccggaacctatggtaaaaaaagcGATTttaatgag ctgatttCGGTATACAGTTGAGACAAGatcttattattcacactttaaaggaggtttc c" /listShort="manP, manA, S439, S440, yjdF, yjdI" /GFF_Attribute="listLong" upshifts complement(1272695) /Source="Nicolas_upshifts" /id="U979" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.748251748251748" /psig="0.14985014985015" /xcortree=304 /SigmaFactorBS="tcggacaagatgtaatcgctaacagtttcataggaaaCCTCC TTTAAAGTGTgaataataagatcttgtctcaactgtataccgaaatcagctcattaaa a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" misc_feature complement(1272704..1272718) /Source="Nicolas_upshift_promotors" /id="U979" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.748251748251748" /psig="0.14985014985015" /xcortree=304 /SigmaFactorBS="tcggacaagatgtaatcgctaacagtttcataggaaaCCTCC TTTAAAGTGTgaataataagatcttgtctcaactgtataccgaaatcagctcattaaa a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" CDS 1272725..1274677 /gene="manP" /locus_tag="BSU_12010" /old_locus_tag="BSU12010" /EC_number="2.7.1.191" /function="16.1: Circulate" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:10627040, 10960106, 23551403" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10627040, 10960106, 23551403; Product type t: transporter" /codon_start=1 /transl_table=11 /product="phosphotransferase system (PTS) mannose-specificenzyme IIBCA component" /protein_id="NP_389083.2" /db_xref="EnsemblGenomes-Gn:BSU12010" /db_xref="EnsemblGenomes-Tr:CAB13058" /db_xref="GOA:O31645" /db_xref="InterPro:IPR002178" /db_xref="InterPro:IPR003352" /db_xref="InterPro:IPR003353" /db_xref="InterPro:IPR003501" /db_xref="InterPro:IPR004715" /db_xref="InterPro:IPR006327" /db_xref="InterPro:IPR013011" /db_xref="InterPro:IPR013014" /db_xref="InterPro:IPR016152" /db_xref="InterPro:IPR036095" /db_xref="PDB:2R48" /db_xref="SubtiList:BG13176" /db_xref="UniProtKB/Swiss-Prot:O31645" /translation="MKLLAITSCPNGIAHTYMAAENLQKAADRLGVSIKVETQGGIGV ENKLTEEEIREADAIIIAADRSVNKDRFIGKKLLSVGVQDGIRKPEELIQKALNGDIP VYRSATKSESGNHQEKKQNPIYRHLMNGVSFMVPFIVVGGLLIAVALTLGGEKTPKGL VIPDDSFWKTIEQIGSASFSFMIPILAGYIAYSIADKPGLVPGMIGGYIAATGSFYDS ASGAGFLGGIIAGFLAGYAALWIKKLKVPKAIQPIMPIIIIPVFASLIVGLAFVFLIG APVAQIFASLTVWLAGMKGSSSILLALILGAMISFDMGGPVNKVAFLFGSAMIGEGNY EIMGPIAVAICIPPIGLGIATFLGKRKFEASQREMGKAAFTMGLFGITEGAIPFAAQD PLRVIPSIMAGSMTGSVIAMIGNVGDRVAHGGPIVAVLGAVDHVLMFFIAVIAGSLVT ALFVNVLKKDITASPVLSETAPTSAPSEAAAANEIKQPIQSQKAEMSEFKKLTDIISP ELIEPNLSGETSDDIIDELIQKLSRRGALLSESGFKQAILNREQQGTTAIGMNIAIPH GKSEAVREPSVAFGIKRSGVDWNSLDGSEAKLIFMIAVPKESGGNQHLKILQMLSRKL MDDNYRERLLSVQTTEEAYKLLEEIE*" gene 1272725..1274677 /gene="manP" /locus_tag="BSU_12010" /old_locus_tag="BSU12010" CDS 1274692..1275639 /gene="manA" /locus_tag="BSU_12020" /old_locus_tag="BSU12020" /EC_number="5.3.1.8" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:10960106, 7934877, 20862359, 23551403" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10960106, 7934877, 20862359, 23551403; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="mannose-6 phosphate isomerase; cupin family" /protein_id="NP_389084.1" /db_xref="EnsemblGenomes-Gn:BSU12020" /db_xref="EnsemblGenomes-Tr:CAB13059" /db_xref="GOA:O31646" /db_xref="InterPro:IPR001250" /db_xref="InterPro:IPR011051" /db_xref="InterPro:IPR014628" /db_xref="InterPro:IPR014710" /db_xref="SubtiList:BG13177" /db_xref="UniProtKB/Swiss-Prot:O31646" /translation="MTTEPLFFKPVFKERIWGGTALADFGYTIPSQRTGECWAFAAHQ NGQSVVQNGMYKGFTLSELWEHHRHLFGQLEGDRFPLLTKILDADQDLSVQVHPNDEY ANIHENGELGKTECWYIIDCQKDAEIIYGHNATTKEELTTMIERGEWDELLRRVKVKP GDFFYVPSGTVHAIGKGILALETQQNSDTTYRLYDYDRKDAEGKLRELHLKKSIEVIE VPSIPERHTVHHEQIEDLLTTTLIECAYFSVGKWNLSGSASLKQQKPFLLISVIEGEG RMISGEYVYPFKKGDHMLLPYGLGEFKLEGYAECIVSHL*" gene 1274692..1275639 /gene="manA" /locus_tag="BSU_12020" /old_locus_tag="BSU12020" S_feature 1275640..1275738 /Source="Nicolas_S_feature" /locus_tag="new_1275640_1275738" /HighExp="Oxctl, Lbexp, Paraq, T0.30H, dia0, Diami, H2O2, dia5, Fru, G150" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.15168699999999999" /TUshortSig="SigA" /TUshortPSig="0.936" /TUlongSig="SigA" /TUlongPSig="0.991" /label="S439" promotor_-35 1275713..1275719 /Source="Nicolas_upshift_promotors" /id="U980" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.463536463536464" /psig="0.995004995004995" /xcortree=2151 /SigmaFactorBS="ctattctccagcaatgatctaaataaaataagaGTTTAATag ttggagaagaaaTGTTACACTCTTTTCTGTATatggtaaagaatgaaaaaacacgatt c" /listShort="S440, yjdF" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1275734..1275753 /Source="Nicolas_upshift_promotors" /id="U980" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.463536463536464" /psig="0.995004995004995" /xcortree=2151 /SigmaFactorBS="ctattctccagcaatgatctaaataaaataagaGTTTAATag ttggagaagaaaTGTTACACTCTTTTCTGTATatggtaaagaatgaaaaaacacgatt c" /listShort="S440, yjdF" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 1275740..1275808 /Source="Nicolas_S_feature" /locus_tag="new_1275740_1275808" /HighExp="Oxctl, Lbexp, Paraq, T0.30H, dia0, Diami, dia5, Fru, H2O2, G150" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="0.995, 0.936" /TUlongSig="SigA" /TUlongPSig="0.991" /label="S440" upshifts 1275740 /Source="Nicolas_upshifts" /id="U980" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.463536463536464" /psig="0.995004995004995" /xcortree=2151 /SigmaFactorBS="ctattctccagcaatgatctaaataaaataagaGTTTAATag ttggagaagaaaTGTTACACTCTTTTCTGTATatggtaaagaatgaaaaaacacgatt c" /listShort="S440, yjdF" /GFF_Attribute="listLong" CDS 1275809..1276291 /gene="yjdF" /locus_tag="BSU_12030" /old_locus_tag="BSU12030" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 20139185" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_389085.1" /db_xref="EnsemblGenomes-Gn:BSU12030" /db_xref="EnsemblGenomes-Tr:CAB13060" /db_xref="InterPro:IPR016787" /db_xref="SubtiList:BG13178" /db_xref="UniProtKB/Swiss-Prot:O31647" /translation="MSVTFPSSGCPSFFNIFYEEGIVMKLTIYYDGQFWVGVVEVVDN GKLRAFRHLFGKEPRDSEVLEFVHNQLLNMMAQAEQEGVRLQGRRQKKINPKRLQRQV SKELKNAGVTSKAQEAIKLELEARKQKKKQIMKEQREHVKEQRYMLKKQKAKKKHRGK *" gene 1275809..1276291 /gene="yjdF" /locus_tag="BSU_12030" /old_locus_tag="BSU12030" downshifts 1276271 /Source="Nicolas_upshifts" /id="D664" /incds=0 /nref=220 /ntot=267 /MaxReadThrough="5.32805" /MaxDrop="7.35641" /score="7.68574519" /energy="-10.2" /TU="U978" /idTUdmin="U980" /TUdmin=1 /isTUend="TRUE" CDS complement(1276337..1276843) /gene="yjdG" /locus_tag="BSU_12040" /old_locus_tag="BSU12040" /EC_number="2.3.1.-" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative acetyltransferase" /protein_id="NP_389086.1" /db_xref="EnsemblGenomes-Gn:BSU12040" /db_xref="EnsemblGenomes-Tr:CAB13061" /db_xref="GOA:O31648" /db_xref="InterPro:IPR000182" /db_xref="InterPro:IPR016181" /db_xref="SubtiList:BG13179" /db_xref="UniProtKB/Swiss-Prot:O31648" /translation="MVLLETNRLRLQTIDIPLLDAASKQDHQAIKELGYETNGEWPNS DFFEAIPYFREILVKNNGTKGFDSWIIVKKDNYEIVGGTGFLGDPDENGMIEIGFATN KSHRRKGYCVEAAQKLINWALSRETVSRITARCEHDNLGSQKTLEKLGFILNHKSAEY KHWIYVTK*" gene complement(1276337..1276843) /gene="yjdG" /locus_tag="BSU_12040" /old_locus_tag="BSU12040" downshifts complement(1276361) /Source="Nicolas_upshifts" /id="D665" /incds=0 /nref=13 /ntot=154 /MaxReadThrough="2.51872" /MaxDrop="4.09551" /score="15.8830125" /energy="-9.9" /TU="NA" /idTUdmin="U984" /TUdmin=7 /isTUend="TRUE" misc_feature complement(1276868..1276887) /Source="Nicolas_upshift_promotors" /id="U981" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.654345654345654" /psig="0.775224775224775" /xcortree=679 /SigmaFactorBS="aattttttcatctttctctactgccaaggtaccagagaaaat tgttaTATGTTATCATTATTCCCAGtaaaaagaaaagaggattaaatatatggttctc c" /listShort="yjdG" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(1276874) /Source="Nicolas_upshifts" /id="U981" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.654345654345654" /psig="0.775224775224775" /xcortree=679 /SigmaFactorBS="aattttttcatctttctctactgccaaggtaccagagaaaat tgttaTATGTTATCATTATTCCCAGtaaaaagaaaagaggattaaatatatggttctc c" /listShort="yjdG" /GFF_Attribute="listLong" S_feature complement(1276876..1277061) /Source="Nicolas_S_feature" /locus_tag="new_1276876_1277061_c" /HighExp="S5, S4, S7, S6, S8, B36, LoTm, S3, B60, T1.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.289238" /TUshortSig="SigEF, SigWXY" /TUshortPSig="0.999, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S441" CDS complement(1277062..1277457) /gene="yjdH" /locus_tag="BSU_12050" /old_locus_tag="BSU12050" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 12562816; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="putative spore coat protein" /protein_id="NP_389087.2" /db_xref="EnsemblGenomes-Gn:BSU12050" /db_xref="EnsemblGenomes-Tr:CAB13062" /db_xref="SubtiList:BG13180" /db_xref="UniProtKB/Swiss-Prot:O31649" /translation="MYHYFYGPALIPYFSHTHNPQRSPDFSERQRRREITLTVDGFVP PSSTEDLGDGFYSYAWTNQQVINPGEYLVCHLEGRDINVINGGFTPRDTAPLYAVASF PRRRNQWVIIIHNPVQTQRAISLYLIAKR*" gene complement(1277062..1277457) /gene="yjdH" /locus_tag="BSU_12050" /old_locus_tag="BSU12050" promotor_-10 complement(1277480..1277498) /Source="Nicolas_upshift_promotors" /id="U982" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1101 /SigmaFactorBS="ctatagcccattattagtctacatggaacaaaacaGGAATGa acaaataactcccACATACAATTTGTATGAATggaaaataaaggagtggttgctttgt a" /listShort="yjdH, S441, yjdG" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1277493) /Source="Nicolas_upshifts" /id="U982" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1101 /SigmaFactorBS="ctatagcccattattagtctacatggaacaaaacaGGAATGa acaaataactcccACATACAATTTGTATGAATggaaaataaaggagtggttgctttgt a" /listShort="yjdH, S441, yjdG" /GFF_Attribute="listLong" S_feature complement(1277495..1278195) /Source="Nicolas_S_feature" /locus_tag="new_1277495_1278195_c" /HighExp="T0.30H, T1.0H, T-0.40H, T1.30H, T0.0H, S0, T2.0H, Salt, T2.30H, T-1.10H" /AntisenseName="yjdI" /AntisenseCor="-0.383915151906285" /AntisenseRegPval="-10.1" /CDS_PredictionProba="NA" /TUshortSig="SigWXY" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S442" promotor_-35 complement(1277513..1277518) /Source="Nicolas_upshift_promotors" /id="U982" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1101 /SigmaFactorBS="ctatagcccattattagtctacatggaacaaaacaGGAATGa acaaataactcccACATACAATTTGTATGAATggaaaataaaggagtggttgctttgt a" /listShort="yjdH, S441, yjdG" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1277601..1277608 /Source="Nicolas_upshift_promotors" /id="U983" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.983016983016983" /psig=1 /xcortree=2214 /SigmaFactorBS="tgtccttccgttgattcaatgctagtaaCCTTGAAAatgcag gttaggaTGATAGAATTTACATATTACtgcaagaagttagacatacatcattttgata g" /listShort="yjdI" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1277622..1277641 /Source="Nicolas_upshift_promotors" /id="U983" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.983016983016983" /psig=1 /xcortree=2214 /SigmaFactorBS="tgtccttccgttgattcaatgctagtaaCCTTGAAAatgcag gttaggaTGATAGAATTTACATATTACtgcaagaagttagacatacatcattttgata g" /listShort="yjdI" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1277633 /Source="Nicolas_upshifts" /id="U983" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.983016983016983" /psig=1 /xcortree=2214 /SigmaFactorBS="tgtccttccgttgattcaatgctagtaaCCTTGAAAatgcag gttaggaTGATAGAATTTACATATTACtgcaagaagttagacatacatcattttgata g" /listShort="yjdI" /GFF_Attribute="listLong" CDS 1277686..1278165 /gene="trnE" /locus_tag="BSU_12060" /old_locus_tag="BSU12060" /function="16.6: Maintain" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 22128149; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="cys-tRNApro deacetylase; tRNA editing" /protein_id="NP_389088.1" /db_xref="EnsemblGenomes-Gn:BSU12060" /db_xref="EnsemblGenomes-Tr:CAB13063" /db_xref="GOA:O31650" /db_xref="InterPro:IPR004369" /db_xref="InterPro:IPR007214" /db_xref="InterPro:IPR036754" /db_xref="SubtiList:BG13181" /db_xref="UniProtKB/Swiss-Prot:O31650" /translation="MAKKMAKTNAVRLIEQQNISYEVLGYKTDGQPVDGISVAEKIGY SLKYVYKTLVAAAGTNHYYVFVVPVAEELDVKKAAKVTGEKKIEMIAMKELLAVTGYL RGGCSPIGMKKLFPTYIDASAETLDFIIVSAGKIGMQLKLAPQDLARSCDAAFAEIV* " gene 1277686..1278165 /gene="trnE" /locus_tag="BSU_12060" /old_locus_tag="BSU12060" downshifts 1278164 /Source="Nicolas_upshifts" /id="D666" /incds=0 /nref=4 /ntot=100 /MaxReadThrough="2.68858" /MaxDrop="3.19616" /score="-5.52314972" /energy="-12.5" /TU="NA" /idTUdmin="U978" /TUdmin=0 /isTUend="TRUE" CDS complement(1278205..1278399) /gene="yjzH" /locus_tag="BSU_12069" /old_locus_tag="BSU12069" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="YP_003097709.1" /db_xref="EnsemblGenomes-Gn:BSU12069" /db_xref="EnsemblGenomes-Tr:CAX52599" /db_xref="InterPro:IPR025234" /db_xref="UniProtKB/Swiss-Prot:C0H3Z2" /translation="MKEYEFVRVELSTMRRRPKEDYQQIIHDYAKRGWRFVQIFAPSI DGYGAAAYFEIIFERDAEKA*" gene complement(1278205..1278399) /gene="yjzH" /locus_tag="BSU_12069" /old_locus_tag="BSU12069" downshifts complement(1278240) /Source="Nicolas_upshifts" /id="D667" /incds=0 /nref=6 /ntot=144 /MaxReadThrough="7.83072" /MaxDrop="2.95935" /score="-6.07514027" /energy="-7" /TU="U984" /idTUdmin="U987" /TUdmin=220 /isTUend="FALSE" promotor_-10 complement(1278413..1278428) /Source="Nicolas_upshift_promotors" /id="U984" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1698 /SigmaFactorBS="tagtgagtgaaatatactttccgaccttaacctaggttttCG GAACTTCTcgctccattttACGTATACCTTAATAGgagggatcaaacgatgaaagaat a" /listShort="yjzH, S442, yjdH, S441, yjdG" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1278429) /Source="Nicolas_upshifts" /id="U984" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1698 /SigmaFactorBS="tagtgagtgaaatatactttccgaccttaacctaggttttCG GAACTTCTcgctccattttACGTATACCTTAATAGgagggatcaaacgatgaaagaat a" /listShort="yjzH, S442, yjdH, S441, yjdG" /GFF_Attribute="listLong" promotor_-35 complement(1278440..1278449) /Source="Nicolas_upshift_promotors" /id="U984" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1698 /SigmaFactorBS="tagtgagtgaaatatactttccgaccttaacctaggttttCG GAACTTCTcgctccattttACGTATACCTTAATAGgagggatcaaacgatgaaagaat a" /listShort="yjzH, S442, yjdH, S441, yjdG" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(1278565..1278894) /gene="yjdJ" /locus_tag="BSU_12070" /old_locus_tag="BSU12070" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_389089.1" /db_xref="EnsemblGenomes-Gn:BSU12070" /db_xref="EnsemblGenomes-Tr:CAB13064" /db_xref="GOA:O31651" /db_xref="InterPro:IPR016508" /db_xref="InterPro:IPR025440" /db_xref="SubtiList:BG13182" /db_xref="UniProtKB/Swiss-Prot:O31651" /translation="MKGIFLVVQLGFSIMVFLFLAAVNWYQGSELVSDRFDWNYTAKL SKLLNGIDAVSSPKQISQLDFFIYSAKHYPVMSALMIISFLYVLAALFLLIYSVKCNK QEIHLDC*" gene complement(1278565..1278894) /gene="yjdJ" /locus_tag="BSU_12070" /old_locus_tag="BSU12070" promotor_-10 complement(1278931..1278950) /Source="Nicolas_upshift_promotors" /id="U985" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.428571428571429" /psig="0.994005994005994" /xcortree=3103 /SigmaFactorBS="aaatagacttgcgtttgagttgtatggaagtgaaATTGCAag aataacccatacGGTGGTAATATATTGTTTGAttttcccatattcatagatttggagg t" /listShort="yjdJ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1278944) /Source="Nicolas_upshifts" /id="U985" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.428571428571429" /psig="0.994005994005994" /xcortree=3103 /SigmaFactorBS="aaatagacttgcgtttgagttgtatggaagtgaaATTGCAag aataacccatacGGTGGTAATATATTGTTTGAttttcccatattcatagatttggagg t" /listShort="yjdJ" /GFF_Attribute="listLong" S_feature complement(1278946..1279513) /Source="Nicolas_S_feature" /locus_tag="new_1278946_1279513_c" /HighExp="S8, S6, nit, S7, ferm, S2, S5, M9-tran, M/G, GM 150" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigK" /TUshortPSig="0.987, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S443" promotor_-35 complement(1278965..1278970) /Source="Nicolas_upshift_promotors" /id="U985" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.428571428571429" /psig="0.994005994005994" /xcortree=3103 /SigmaFactorBS="aaatagacttgcgtttgagttgtatggaagtgaaATTGCAag aataacccatacGGTGGTAATATATTGTTTGAttttcccatattcatagatttggagg t" /listShort="yjdJ" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1278998..1279002 /Source="Nicolas_upshift_promotors" /id="U986" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.913086913086913" /psig="0.996003996003996" /xcortree=2745 /SigmaFactorBS="tcttgcaatttcacttccatacaactcaaacgcaagTCTATt tttttgtttgttttTGGCTTATAATACCTGATGAtggaaaaagagtgcgggtttatag a" /listShort="S444" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1279018..1279037 /Source="Nicolas_upshift_promotors" /id="U986" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.913086913086913" /psig="0.996003996003996" /xcortree=2745 /SigmaFactorBS="tcttgcaatttcacttccatacaactcaaacgcaagTCTATt tttttgtttgttttTGGCTTATAATACCTGATGAtggaaaaagagtgcgggtttatag a" /listShort="S444" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 1279022..1279523 /Source="Nicolas_S_feature" /locus_tag="new_1279022_1279523" /HighExp="LBGstat, C30, HPh, Oxctl, dia15, Paraq, T0.30H, C90, LBGtran, LPh" /AntisenseName="ctaO" /AntisenseCor="-0.43946575370083102" /AntisenseRegPval="-13.4" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.996" /TUlongSig="NA" /TUlongPSig="NA" /label="S444" upshifts 1279022 /Source="Nicolas_upshifts" /id="U986" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.913086913086913" /psig="0.996003996003996" /xcortree=2745 /SigmaFactorBS="tcttgcaatttcacttccatacaactcaaacgcaagTCTATt tttttgtttgttttTGGCTTATAATACCTGATGAtggaaaaagagtgcgggtttatag a" /listShort="S444" /GFF_Attribute="listLong" CDS complement(1279514..1280503) /gene="ctaO" /locus_tag="BSU_12080" /old_locus_tag="BSU12080" /EC_number="2.5.1.-" /function="16.10: Respire" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:10675592, 15491161, 15849754, 16850406" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10675592, 15491161, 15849754, 16850406; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="minor protoheme IX farnesyltransferase 1 (heme Osynthase)" /protein_id="NP_389090.2" /db_xref="EnsemblGenomes-Gn:BSU12080" /db_xref="EnsemblGenomes-Tr:CAB13065" /db_xref="GOA:O31652" /db_xref="InterPro:IPR000537" /db_xref="InterPro:IPR006369" /db_xref="InterPro:IPR030470" /db_xref="SubtiList:BG13183" /db_xref="UniProtKB/Swiss-Prot:O31652" /translation="MQFWGRRLFLENTRDSAAISETKYIKASNRVTIYDFIKLAKPGI IISNSIAAFGGFWIAFASAEKTLTGLAFLMTMVTAMLGTAFVMASGTVYNNYFDRHMD AKMARTRSRASVTGKMPPAMILTYGSVLGIAGLAMLYSLNPLTAFLGLAAFIFYAIIY TVWVKRTSVWSTFVGSFPGAAPPLMGYCAVTGDFSMTAVLLYTIMFLWQPPHFWAIGI RRKEEYRAAGVPLLPVVKGNHVTKIKMMQYIAVLVPVTLLFPFSLGTGHISPFYFLAA LVLGGIWIKKSIKGFKTDDDVKWAKDMFVYSLIYFCLLFFIMMIDSFMMFLIR*" gene complement(1279514..1280503) /gene="ctaO" /locus_tag="BSU_12080" /old_locus_tag="BSU12080" promotor_-10 complement(1280504..1280523) /Source="Nicolas_upshift_promotors" /id="U987" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.36963036963037" /psig="0.987012987012987" /xcortree=2978 /SigmaFactorBS="aatatcatgacaaatatgggaaataATTGTGattctgtcccc ctCTTGTTACGATAACAAAAGCatgcagttttgggggaggcgtctatttttggagaat a" /listShort="ctaO, S443, yjdJ" /listLong="yjzH" /label="promotor_-10" upshifts complement(1280507) /Source="Nicolas_upshifts" /id="U987" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.36963036963037" /psig="0.987012987012987" /xcortree=2978 /SigmaFactorBS="aatatcatgacaaatatgggaaataATTGTGattctgtcccc ctCTTGTTACGATAACAAAAGCatgcagttttgggggaggcgtctatttttggagaat a" /listShort="ctaO, S443, yjdJ" /listLong="yjzH" promotor_-35 complement(1280537..1280542) /Source="Nicolas_upshift_promotors" /id="U987" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.36963036963037" /psig="0.987012987012987" /xcortree=2978 /SigmaFactorBS="aatatcatgacaaatatgggaaataATTGTGattctgtcccc ctCTTGTTACGATAACAAAAGCatgcagttttgggggaggcgtctatttttggagaat a" /listShort="ctaO, S443, yjdJ" /listLong="yjzH" /label="promotor_-35" CDS complement(1280626..1280874) /gene="cotT" /locus_tag="BSU_12090" /old_locus_tag="BSU12090" /function="16.5: Explore" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:1391045, 1917883, 19933362" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1391045, 1917883, 19933362; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="spore coat protein (inner coat)" /protein_id="NP_389091.2" /db_xref="EnsemblGenomes-Gn:BSU12090" /db_xref="EnsemblGenomes-Tr:CAB13066" /db_xref="GOA:P11863" /db_xref="SubtiList:BG10495" /db_xref="UniProtKB/Swiss-Prot:P11863" /translation="MDYPLNEQSFEQITPYDERQPYYYPRPRPPFYPPYYYPRPYYPF YPFYPRPPYYYPRPRPPYYPWYGYGGGYGGGYGGGYGY*" gene complement(1280626..1280874) /gene="cotT" /locus_tag="BSU_12090" /old_locus_tag="BSU12090" downshifts complement(1280636) /Source="Nicolas_upshifts" /id="D668" /incds=0 /nref=37 /ntot=82 /MaxReadThrough="5.73194" /MaxDrop="6.23577" /score="25.0951218" /energy="-8.4" /TU="U989" /idTUdmin="U990" /TUdmin=2 /isTUend="TRUE" promotor_-35 1280870..1280874 /Source="Nicolas_upshift_promotors" /id="U988" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp=1 /psig=0 /xcortree=705 /SigmaFactorBS="gggtaatttgttcaaatgactgttcattcaaagggtaaTCCA AgaggaaaaCCTCCCTAGCTTTTTttattccttttaccatattcctgatgcttaagtt g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1280883..1280897 /Source="Nicolas_upshift_promotors" /id="U988" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp=1 /psig=0 /xcortree=705 /SigmaFactorBS="gggtaatttgttcaaatgactgttcattcaaagggtaaTCCA AgaggaaaaCCTCCCTAGCTTTTTttattccttttaccatattcctgatgcttaagtt g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1280892 /Source="Nicolas_upshifts" /id="U988" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp=1 /psig=0 /xcortree=705 /SigmaFactorBS="gggtaatttgttcaaatgactgttcattcaaagggtaaTCCA AgaggaaaaCCTCCCTAGCTTTTTttattccttttaccatattcctgatgcttaagtt g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 complement(1280899..1280918) /Source="Nicolas_upshift_promotors" /id="U989" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1278 /SigmaFactorBS="ataaaaaaaaccgaatttcatgaatgtACATACACCCaactt aagcatcaGGAATATGGTAAAAGGAATAaaaaaagctagggaggttttcctcttggat t" /listShort="cotT, ctaO, S443" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1280908) /Source="Nicolas_upshifts" /id="U989" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1278 /SigmaFactorBS="ataaaaaaaaccgaatttcatgaatgtACATACACCCaactt aagcatcaGGAATATGGTAAAAGGAATAaaaaaagctagggaggttttcctcttggat t" /listShort="cotT, ctaO, S443" /GFF_Attribute="listLong" promotor_-35 complement(1280932..1280941) /Source="Nicolas_upshift_promotors" /id="U989" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1278 /SigmaFactorBS="ataaaaaaaaccgaatttcatgaatgtACATACACCCaactt aagcatcaGGAATATGGTAAAAGGAATAaaaaaagctagggaggttttcctcttggat t" /listShort="cotT, ctaO, S443" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1280989..1280996 /Source="Nicolas_upshift_promotors" /id="U991" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.713286713286713" /psig="0.994005994005994" /xcortree=1545 /SigmaFactorBS="ttttatgatgaaattccttaaaaaggATTGACATgaacttct aaatcTCATAGTATTACAAATGTGAaataaatgttactacaatgttacaaaaacattt c" /listShort="S445, yjeA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(1281003..1281022) /Source="Nicolas_upshift_promotors" /id="U990" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.433566433566434" /psig="0.684315684315684" /xcortree=2052 /SigmaFactorBS="atctatttagaaatgtttttgtaacattgTAGTAACAtttat ttcacattTGTAATACTATGAGATTTAGaagttcatgtcaatcctttttaaggaattt c" /listShort="cotT" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-10 1281010..1281029 /Source="Nicolas_upshift_promotors" /id="U991" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.713286713286713" /psig="0.994005994005994" /xcortree=1545 /SigmaFactorBS="ttttatgatgaaattccttaaaaaggATTGACATgaacttct aaatcTCATAGTATTACAAATGTGAaataaatgttactacaatgttacaaaaacattt c" /listShort="S445, yjeA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1281012) /Source="Nicolas_upshifts" /id="U990" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.433566433566434" /psig="0.684315684315684" /xcortree=2052 /SigmaFactorBS="atctatttagaaatgtttttgtaacattgTAGTAACAtttat ttcacattTGTAATACTATGAGATTTAGaagttcatgtcaatcctttttaaggaattt c" /listShort="cotT" /GFF_Attribute="listLong" upshifts 1281023 /Source="Nicolas_upshifts" /id="U991" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.713286713286713" /psig="0.994005994005994" /xcortree=1545 /SigmaFactorBS="ttttatgatgaaattccttaaaaaggATTGACATgaacttct aaatcTCATAGTATTACAAATGTGAaataaatgttactacaatgttacaaaaacattt c" /listShort="S445, yjeA" /GFF_Attribute="listLong" S_feature 1281024..1281127 /Source="Nicolas_S_feature" /locus_tag="new_1281024_1281127" /HighExp="Heat, T0.30H, T1.0H, ferm, Diami, dia5, T1.30H, M9-stat, T3.0H, T2.30H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.994" /TUlongSig="NA" /TUlongPSig="NA" /label="S445" promotor_-35 complement(1281036..1281043) /Source="Nicolas_upshift_promotors" /id="U990" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.433566433566434" /psig="0.684315684315684" /xcortree=2052 /SigmaFactorBS="atctatttagaaatgtttttgtaacattgTAGTAACAtttat ttcacattTGTAATACTATGAGATTTAGaagttcatgtcaatcctttttaaggaattt c" /listShort="cotT" /GFF_Attribute="listLong" /label="promotor_-35" CDS 1281128..1282531 /gene="pdaC" /locus_tag="BSU_12100" /old_locus_tag="BSU12100" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:14679227, 17878218, 22277649" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 14679227, 17878218, 22277649; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="N-acetylmuramic acid deacetylase" /protein_id="NP_389092.1" /db_xref="EnsemblGenomes-Gn:BSU12100" /db_xref="EnsemblGenomes-Tr:CAB13067" /db_xref="GOA:O34798" /db_xref="InterPro:IPR002509" /db_xref="InterPro:IPR011330" /db_xref="InterPro:IPR017219" /db_xref="InterPro:IPR021729" /db_xref="InterPro:IPR025303" /db_xref="InterPro:IPR037126" /db_xref="SubtiList:BG13184" /db_xref="UniProtKB/Swiss-Prot:O34798" /translation="MLAKRIKWFHVLIAVVCVVGLIGFFHNHSLKKETVMNKVRTDSQ YGNVEIATLVNDGKTFNYAVNYPVFKNEKMDSALKRFAEKEVRQFQKETKDVDQEHTT KRNELNVDYKIVHYAKQTVAIVFNEYKYIGGAHGQTVKKTFNYDFSKQAFLSIDDIFK EDADYLHKLSLIAYHELKKNKDIAADDALLKEGTAPKKENFSRFAIKEDYIELYFDTY QVAAGYLGEQSIAIKKSLLKDILKEQYIDKAKNKNKIKEQKPKHEVISLPKEETVDPN QKVIALTFDDGPNPATTNQILDSLKKYKGHATFFVLGSRVQYYPETLIRMLKEGNEVG NHSWSHPLLTRLSVKEALKQINDTQDIIEKISGYRPTLVRPPYGGINDELRSQMKMDV ALWDVDPEDWKDRNKKTIVDRVMNQAGDGRTILIHDIYRTSADAADEIIKKLTDQGYQ LVTVSQLEEVKKQREAK*" gene 1281128..1282531 /gene="pdaC" /locus_tag="BSU_12100" /old_locus_tag="BSU12100" downshifts 1282520 /Source="Nicolas_upshifts" /id="D669" /incds=0 /nref=173 /ntot=238 /MaxReadThrough="1.38483" /MaxDrop="6.60322" /score="39.935002" /energy="-13.8" /TU="NA" /idTUdmin="U991" /TUdmin=0 /isTUend="TRUE" CDS complement(1282571..1283044) /gene="yjfA" /locus_tag="BSU_12110" /old_locus_tag="BSU12110" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_389093.1" /db_xref="EnsemblGenomes-Gn:BSU12110" /db_xref="EnsemblGenomes-Tr:CAB13068" /db_xref="InterPro:IPR021224" /db_xref="SubtiList:BG13185" /db_xref="UniProtKB/Swiss-Prot:O34554" /translation="MKRLFMKASLVLFAVVFVFAVKGAPAKAETHAYDGKSPYYNDCA SSGSTKKSSNLVNASNQVIGVVELKFSSTCKTAWAKITMNNTLTSGYEANAEITRNTD GKRYNCDSAGGNGKAVAGQKSCYTPMVYDLDPRTSYAFGKYSGPNLNVWATTGSY*" gene complement(1282571..1283044) /gene="yjfA" /locus_tag="BSU_12110" /old_locus_tag="BSU12110" downshifts complement(1282575) /Source="Nicolas_upshifts" /id="D670" /incds=0 /nref=33 /ntot=176 /MaxReadThrough="2.25434" /MaxDrop="5.38548" /score="20.5383759" /energy="-13.8" /TU="NA" /idTUdmin="U992" /TUdmin="-1" /isTUend="TRUE" promotor_-10 complement(1283066..1283084) /Source="Nicolas_upshift_promotors" /id="U992" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.994005994005994" /psig="0.994005994005994" /xcortree=1105 /SigmaFactorBS="ctccatcctcccggccgcctttattgttcacaaaaaagcaTG CATGttttgattgttcctCCATATGATTTATTGTTTGccatattaaggaggtcataaa t" /listShort="yjfA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1283084) /Source="Nicolas_upshifts" /id="U992" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.994005994005994" /psig="0.994005994005994" /xcortree=1105 /SigmaFactorBS="ctccatcctcccggccgcctttattgttcacaaaaaagcaTG CATGttttgattgttcctCCATATGATTTATTGTTTGccatattaaggaggtcataaa t" /listShort="yjfA" /GFF_Attribute="listLong" promotor_-35 complement(1283099..1283104) /Source="Nicolas_upshift_promotors" /id="U992" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.994005994005994" /psig="0.994005994005994" /xcortree=1105 /SigmaFactorBS="ctccatcctcccggccgcctttattgttcacaaaaaagcaTG CATGttttgattgttcctCCATATGATTTATTGTTTGccatattaaggaggtcataaa t" /listShort="yjfA" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(1283169..1283336) /gene="yjfB" /locus_tag="BSU_12120" /old_locus_tag="BSU12120" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 15033535" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_389094.1" /db_xref="EnsemblGenomes-Gn:BSU12120" /db_xref="EnsemblGenomes-Tr:CAB13069" /db_xref="InterPro:IPR025906" /db_xref="SubtiList:BG13186" /db_xref="UniProtKB/Swiss-Prot:O34438" /translation="MDIPALSVAMHQASLAQNVNIALTKKRLDTAQQNADQTLKMIQH PTLGQTIDVKA*" gene complement(1283169..1283336) /gene="yjfB" /locus_tag="BSU_12120" /old_locus_tag="BSU12120" downshifts complement(1283172) /Source="Nicolas_upshifts" /id="D671" /incds=0 /nref=109 /ntot=232 /MaxReadThrough="3.53249" /MaxDrop="4.93218" /score="-9.08395816" /energy="-13.9" /TU="U993" /idTUdmin="U993" /TUdmin="-576" /isTUend="FALSE" promotor_-10 complement(1283348..1283366) /Source="Nicolas_upshift_promotors" /id="U993" /multdbtbs="SigD" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2829 /SigmaFactorBS="gggtcaacaagagaaattaagccatttttcaCTGTAAAAtca tacaaacccGCCGATAGGTAAGGCATAGgaggtggaaccatggatattcctgctttat c" /listShort="yjfB, yjfA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1283357) /Source="Nicolas_upshifts" /id="U993" /multdbtbs="SigD" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2829 /SigmaFactorBS="gggtcaacaagagaaattaagccatttttcaCTGTAAAAtca tacaaacccGCCGATAGGTAAGGCATAGgaggtggaaccatggatattcctgctttat c" /listShort="yjfB, yjfA" /GFF_Attribute="listLong" promotor_-35 complement(1283379..1283386) /Source="Nicolas_upshift_promotors" /id="U993" /multdbtbs="SigD" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2829 /SigmaFactorBS="gggtcaacaagagaaattaagccatttttcaCTGTAAAAtca tacaaacccGCCGATAGGTAAGGCATAGgaggtggaaccatggatattcctgctttat c" /listShort="yjfB, yjfA" /GFF_Attribute="listLong" /label="promotor_-35" CDS 1283463..1284362 /gene="yjfC" /locus_tag="BSU_12130" /old_locus_tag="BSU12130" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_389095.2" /db_xref="EnsemblGenomes-Gn:BSU12130" /db_xref="EnsemblGenomes-Tr:CAB13070" /db_xref="InterPro:IPR018728" /db_xref="SubtiList:BG13187" /db_xref="UniProtKB/Swiss-Prot:O34458" /translation="MNLVMEKTFEQYEKLFSMEEQKREDVFRYTMMRPFEKMWTAIQV PLKAKEPNGYDVIMAAKMLGYLDVRDAESGQKALQILKESHVSETAESALRQCIFFAE REQLRVNAKEIKFGLYIADPNKLQLQKGYCGFGGIPGFIHVWINPNSYNLPRIPSIIA HEFHHNVRFSYIDFHHGSVSVGDYLVIEGLAESFARELFGTERLGPWVTRFDHEDLQY SIDVINEVLDVKGFSEVSRYMFGDPIANDQGFKPAGLSAFAGYAVGYHAVQSFMNQHH ITISEATRLDAKTIISQCGLFST*" gene 1283463..1284362 /gene="yjfC" /locus_tag="BSU_12130" /old_locus_tag="BSU12130" CDS complement(1284371..1284769) /gene="yjgA" /locus_tag="BSU_12140" /old_locus_tag="BSU12140" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 15849754, 16850406" /codon_start=1 /transl_table=11 /product="conserved membrane protein" /protein_id="NP_389096.1" /db_xref="EnsemblGenomes-Gn:BSU12140" /db_xref="EnsemblGenomes-Tr:CAB13071" /db_xref="GOA:O35027" /db_xref="InterPro:IPR021257" /db_xref="SubtiList:BG13188" /db_xref="UniProtKB/Swiss-Prot:O35027" /translation="MKRNRWIYAVFTILIIGLGLGSRAFSSVLPDTLNTYLGDSLWAA MIFTGCGFLFRKLKTMITGIISLSFCFVIEFSQLYHAEWIDQIRDTSLGGLVLGYGFL WSDIEAYTIGIAACAAIELLVLGIKKRRCM*" gene complement(1284371..1284769) /gene="yjgA" /locus_tag="BSU_12140" /old_locus_tag="BSU12140" downshifts complement(1284401) /Source="Nicolas_upshifts" /id="D672" /incds=0 /nref=2 /ntot=27 /MaxReadThrough="2.86089" /MaxDrop="2.52307" /score="23.8106216" /energy="-10.1" /TU="U994,U995" /idTUdmin="U995" /TUdmin="-243" /isTUend="FALSE" promotor_-10 complement(1284798..1284817) /Source="Nicolas_upshift_promotors" /id="U994" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.915084915084915" /psig=1 /xcortree=1954 /SigmaFactorBS="caaaataaacaccctacgcggctattcagccgctttttTAGT GGACaaataaaagctataTTCCTTACAATACAGGGAGAtgaagcagagacggggtatc a" /listShort="yjgA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1284817) /Source="Nicolas_upshifts" /id="U994" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.915084915084915" /psig=1 /xcortree=1954 /SigmaFactorBS="caaaataaacaccctacgcggctattcagccgctttttTAGT GGACaaataaaagctataTTCCTTACAATACAGGGAGAtgaagcagagacggggtatc a" /listShort="yjgA" /GFF_Attribute="listLong" promotor_-35 complement(1284832..1284839) /Source="Nicolas_upshift_promotors" /id="U994" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.915084915084915" /psig=1 /xcortree=1954 /SigmaFactorBS="caaaataaacaccctacgcggctattcagccgctttttTAGT GGACaaataaaagctataTTCCTTACAATACAGGGAGAtgaagcagagacggggtatc a" /listShort="yjgA" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(1284870..1285445) /gene="yjgB" /locus_tag="BSU_12150" /old_locus_tag="BSU12150" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 1580552" /codon_start=1 /transl_table=11 /product="putative exported protein" /protein_id="NP_389097.1" /db_xref="EnsemblGenomes-Gn:BSU12150" /db_xref="EnsemblGenomes-Tr:CAB13072" /db_xref="InterPro:IPR025453" /db_xref="PDB:4YGT" /db_xref="SubtiList:BG13189" /db_xref="UniProtKB/Swiss-Prot:O34960" /translation="MKKTMSAITAAAAVTSCFTGFGAASFSAPAKAAAQTNTLSENTN QSAAELVKNLYNTAYKGEMPQQAQGLTINKSTKGDVHAAFGEPERPVGGDNRFDLYHW NMGQPGYGFSYHKDMTISEIRYFGTGVERQLNLGGVTPEVLQKQLGPVNRVLTVPFTD EIDYVYDTGRYELHFVIGTDQTADHVNLKAK*" gene complement(1284870..1285445) /gene="yjgB" /locus_tag="BSU_12150" /old_locus_tag="BSU12150" downshifts complement(1284885) /Source="Nicolas_upshifts" /id="D673" /incds=0 /nref=3 /ntot=16 /MaxReadThrough="5.38565" /MaxDrop="3.9021" /score="23.8106216" /energy="-10.1" /TU="U995" /idTUdmin="U995" /TUdmin="-727" /isTUend="FALSE" promotor_-10 complement(1285464..1285482) /Source="Nicolas_upshift_promotors" /id="U995" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=183 /SigmaFactorBS="tacaacaactcaataaaacatacaaagcgcactcacaTGTTT CGttgcaaaaacacgGGGAAACGGAATGGTAGATcaattaggagggattaacatgaaa a" /listShort="yjgB, yjgA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1285479) /Source="Nicolas_upshifts" /id="U995" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=183 /SigmaFactorBS="tacaacaactcaataaaacatacaaagcgcactcacaTGTTT CGttgcaaaaacacgGGGAAACGGAATGGTAGATcaattaggagggattaacatgaaa a" /listShort="yjgB, yjgA" /GFF_Attribute="listLong" promotor_-35 complement(1285496..1285502) /Source="Nicolas_upshift_promotors" /id="U995" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=183 /SigmaFactorBS="tacaacaactcaataaaacatacaaagcgcactcacaTGTTT CGttgcaaaaacacgGGGAAACGGAATGGTAGATcaattaggagggattaacatgaaa a" /listShort="yjgB, yjgA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1285520..1285526 /Source="Nicolas_upshift_promotors" /id="U996" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=186 /SigmaFactorBS="ccgtgtttttgcaacgaaacatgtgagtgcgctttgtaTGTT TTAttgagttgttgtaaGGGAACTGAAATAGGTAATtcggtatataaagcaagaaagg g" /listShort="yjgC, yjgD, S446, yjhA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1285541..1285559 /Source="Nicolas_upshift_promotors" /id="U996" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=186 /SigmaFactorBS="ccgtgtttttgcaacgaaacatgtgagtgcgctttgtaTGTT TTAttgagttgttgtaaGGGAACTGAAATAGGTAATtcggtatataaagcaagaaagg g" /listShort="yjgC, yjgD, S446, yjhA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1285542 /Source="Nicolas_upshifts" /id="U996" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=186 /SigmaFactorBS="ccgtgtttttgcaacgaaacatgtgagtgcgctttgtaTGTT TTAttgagttgttgtaaGGGAACTGAAATAGGTAATtcggtatataaagcaagaaagg g" /listShort="yjgC, yjgD, S446, yjhA" /GFF_Attribute="listLong" CDS 1285591..1288548 /gene="yjgC" /locus_tag="BSU_12160" /old_locus_tag="BSU12160" /EC_number="1.2.1.-" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative molybdoenzyme; putative formate dehydrogenase" /protein_id="NP_389098.1" /db_xref="EnsemblGenomes-Gn:BSU12160" /db_xref="EnsemblGenomes-Tr:CAB13073" /db_xref="GOA:O34720" /db_xref="InterPro:IPR001041" /db_xref="InterPro:IPR006478" /db_xref="InterPro:IPR006656" /db_xref="InterPro:IPR006657" /db_xref="InterPro:IPR006963" /db_xref="InterPro:IPR009010" /db_xref="InterPro:IPR012675" /db_xref="InterPro:IPR017896" /db_xref="InterPro:IPR017900" /db_xref="InterPro:IPR019574" /db_xref="InterPro:IPR036010" /db_xref="SubtiList:BG13190" /db_xref="UniProtKB/Swiss-Prot:O34720" /translation="MAGKKTITINGVEMEASEEQTVLQLLNNSSIEVPQVCYHPSLGP IETCDTCIVSINGELKRSCSAELKDGDVIDTLSPDVKKAQVIGMDKILYNHELYCTVC DYNNGGCEIHNTVKEMKINHQSIPFDHKPYHKDESHPFYRYDPDQCILCGRCVEACQD VQVTETLTIDWERKRPRVIWDNDVPINESSCVSCGHCSTVCPCNAMMEKGMEGEAGYL TGINNETLRPMIEITKGVETGYGSILAISDMESAMRDERIKKTKTVCTYCGVGCSFDV WTKGRDILKVEPQEEAPANGISTCVKGKFGWDFVNSEERLTKPLIREGDHFREAEWEE ALLLIASKFTELKEAFGPDSLAFITSSKCTNEESYLMQKLARGVIGTNNVDNCSRYCQ SPATAGLFRTVGYGGDSGSITDIAQADLVLIIGSNTSESHPVLSTRIKRAHKLRGQKV IVADIRKHEMAERSDLFVQPRAGSDIVWLNAIAKYLIENGKADERFLRERVNGRDEYV KSLAPYTLEYAEEKTGIDQETLIQMAEMIGQADSVCALWAMGVTQHIGGSDTSTAISN LLLVTGNYGKPGAGSYPLRGHNNVQGASDFGSMPDRLPGYEKVTDEQVRQKYERVWGV PLPKEPGMTNHEMIEKIHSGQLKAMYVKGEEMGLVDSNINHVHAAYEKLDFFVVQDIF LSRTAEFADVVLPASPSLEKEGTFTNTERRIQRLYQVFEPLGESKPDWQIIMEVANKL GAGWLYEHPADIMEEAAKLSPIYAGVTYERLEGYNSLQWPVNADGKDSPLLFTERFPF PDGKAILYPVQWTEPKEFGEEYDIHVNNGRLLEHFHEGNLTYKSKGISEKTPEVFLEI SPELAAERGIQDGTLVRLTSPFGNVKVKCLITDRVKGKEVYLPMNDSGEAAINLLTGS HADKDTDTPAYKETSAKMEILKHDGISPLPKINHRNGNPQPQIGVQVHKKWARKDYIF PGDAVKRGMGHNG*" gene 1285591..1288548 /gene="yjgC" /locus_tag="BSU_12160" /old_locus_tag="BSU12160" CDS 1288541..1289101 /gene="yjgD" /locus_tag="BSU_12170" /old_locus_tag="BSU12170" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_389099.1" /db_xref="EnsemblGenomes-Gn:BSU12170" /db_xref="EnsemblGenomes-Tr:CAB13074" /db_xref="InterPro:IPR012440" /db_xref="SubtiList:BG13191" /db_xref="UniProtKB/Swiss-Prot:O34681" /translation="MAKAIKRIQKIEVTEEDQRKRDLREIEDALIDHKEAILETLHML GHMNERGVLPLLRGLFGQGDKVLDILVKKADTEETANTLKNLLLLFGTLGMLDVKQLE PLILKVNAGVASAVEQKNSEEKTGYFDIIRSLKDPEINKSITLLFSFLKGMGQDTKEL ERTTQPPEHQKHHQEPREKRGMNKRD*" gene 1288541..1289101 /gene="yjgD" /locus_tag="BSU_12170" /old_locus_tag="BSU12170" downshifts 1289094 /Source="Nicolas_upshifts" /id="D674" /incds=0 /nref=18 /ntot=84 /MaxReadThrough="5.25706" /MaxDrop="6.46184" /score="20.7921843" /energy="-15" /TU="U996" /idTUdmin="U996" /TUdmin="-819" /isTUend="FALSE" S_feature 1289139..1289257 /Source="Nicolas_S_feature" /locus_tag="new_1289139_1289257" /HighExp="Etha, Salt, Heat, S8, M9-stat, S7, LPhT, G135, C30, Sw" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigB" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S446" promotor_-35 1289235..1289238 /Source="Nicolas_upshift_promotors" /id="U997" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.779220779220779" /psig="0.998001998001998" /xcortree=2980 /SigmaFactorBS="tgatgaatgagatagaaataatcgttactttcttacCTGTta agaaaagggaaaaTCTGATTATAATAGAAATCGattactttagatgggggaacaatca t" /listShort="yjhA, yjhB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1289254..1289273 /Source="Nicolas_upshift_promotors" /id="U997" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.779220779220779" /psig="0.998001998001998" /xcortree=2980 /SigmaFactorBS="tgatgaatgagatagaaataatcgttactttcttacCTGTta agaaaagggaaaaTCTGATTATAATAGAAATCGattactttagatgggggaacaatca t" /listShort="yjhA, yjhB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1289259 /Source="Nicolas_upshifts" /id="U997" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.779220779220779" /psig="0.998001998001998" /xcortree=2980 /SigmaFactorBS="tgatgaatgagatagaaataatcgttactttcttacCTGTta agaaaagggaaaaTCTGATTATAATAGAAATCGattactttagatgggggaacaatca t" /listShort="yjhA, yjhB" /GFF_Attribute="listLong" CDS 1289298..1289939 /gene="yjhA" /locus_tag="BSU_12180" /old_locus_tag="BSU12180" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type lp: lipoprotein" /codon_start=1 /transl_table=11 /product="putative lipoprotein" /protein_id="NP_389100.1" /db_xref="EnsemblGenomes-Gn:BSU12180" /db_xref="EnsemblGenomes-Tr:CAB13075" /db_xref="GOA:O34725" /db_xref="InterPro:IPR029050" /db_xref="InterPro:IPR029051" /db_xref="PDB:3CFU" /db_xref="SubtiList:BG13192" /db_xref="UniProtKB/Swiss-Prot:O34725" /translation="MKKVLLLLFVLTIGLALSACSQSSDASEKEKPKEKKSQEELEKE LDKELKKGGEPKTKKDDQIHKIGETFKAGHTNFTVNKVDRVQKGEYMNVGGAVNEETK TIKDDEERLIIEVTMENIGEDSISYNFIGFDLRDKNDQSVRPVFSIEEKGRILMGGTL VSGKKVTGVLSYVIPKGEQKHYTLVYNPFLADTNSSNTEERVKDDIDYLVKLD*" gene 1289298..1289939 /gene="yjhA" /locus_tag="BSU_12180" /old_locus_tag="BSU12180" downshifts complement(1289307) /Source="Nicolas_upshifts" /id="D675" /incds=0 /nref=7 /ntot=57 /MaxReadThrough="2.5769" /MaxDrop="3.81596" /score="-9.34186213" /energy="-3" /TU="NA" /idTUdmin="U998" /TUdmin=1386 /isTUend="FALSE" downshifts 1289912 /Source="Nicolas_upshifts" /id="D676" /incds=0 /nref=24 /ntot=186 /MaxReadThrough="4.29897" /MaxDrop="3.4683" /score="19.6571267" /energy="-17" /TU="U997" /idTUdmin="U996" /TUdmin="-1" /isTUend="TRUE" CDS 1290018..1290644 /gene="yjhB" /locus_tag="BSU_12190" /old_locus_tag="BSU12190" /EC_number="3.6.1.-" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 12483591, 16513759; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative ADP-ribose pyrophosphatase" /protein_id="NP_389101.2" /db_xref="EnsemblGenomes-Gn:BSU12190" /db_xref="EnsemblGenomes-Tr:CAB13076" /db_xref="GOA:C0SPC3" /db_xref="InterPro:IPR000086" /db_xref="InterPro:IPR015797" /db_xref="SubtiList:BG13193" /db_xref="UniProtKB/Swiss-Prot:C0SPC3" /translation="MIKVQTKWLERAQRIRAIAQAGLAFSKDVYDRERYEELMKLSAE MMADYSEKDIEVITDLWQGEKGYPTPKADVRGAVFRENQILLVREKHDELWSLPGGFC EIGLSPAENVVKEIKEESGYDTEPSRLLAVLDSHKHSHPPQPYHYYKIFIACSMTDGQ GETGIETNHAAFFPEDRLPPLSPKRNTPSQLSMLFDFLRHPDKKTIFD*" gene 1290018..1290644 /gene="yjhB" /locus_tag="BSU_12190" /old_locus_tag="BSU12190" downshifts 1290646 /Source="Nicolas_upshifts" /id="D677" /incds=0 /nref=97 /ntot=202 /MaxReadThrough="0.597580000000001" /MaxDrop="6.62023" /score="12.2319602" /energy="-7" /TU="NA" /idTUdmin="U997" /TUdmin=7 /isTUend="TRUE" downshifts complement(1290649) /Source="Nicolas_upshifts" /id="D678" /incds=0 /nref=1 /ntot=9 /MaxReadThrough="0.18907" /MaxDrop="3.31161" /score="10.5815896" /energy="-7" /TU="NA" /idTUdmin="U998" /TUdmin=44 /isTUend="FALSE" CDS complement(1290675..1290953) /gene="yjiA" /locus_tag="BSU_12200" /old_locus_tag="BSU12200" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function; PubMedId : 14563871" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="NP_389102.1" /db_xref="EnsemblGenomes-Gn:BSU12200" /db_xref="EnsemblGenomes-Tr:CAB13077" /db_xref="SubtiList:BG13194" /db_xref="UniProtKB/Swiss-Prot:O34679" /translation="MAAQTDYKKQVVGILLSLAFVLFVFSFSERHEKPLVEGKKQENW HTVVDKASVKIYGSRLVEENKLKQKLGHKQADSILTLLKLANEKHITL*" gene complement(1290675..1290953) /gene="yjiA" /locus_tag="BSU_12200" /old_locus_tag="BSU12200" downshifts complement(1290693) /Source="Nicolas_upshifts" /id="D679" /incds=0 /nref=162 /ntot=247 /MaxReadThrough="1.96302" /MaxDrop="5.98058" /score="10.5815896" /energy="-7" /TU="NA" /idTUdmin="U998" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(1290982..1290993) /Source="Nicolas_upshift_promotors" /id="U998" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.632367632367632" /psig="0.972027972027972" /xcortree=575 /SigmaFactorBS="gtctctgttttcaaccaaatgcactaactccaaaaatgactt tcccattatgtaaaataaTTTGGTTcTATGATTAAATAgaaggtaaaaggtgaaggag a" /listShort="yjiA" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 complement(1290995..1291001) /Source="Nicolas_upshift_promotors" /id="U998" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.632367632367632" /psig="0.972027972027972" /xcortree=575 /SigmaFactorBS="gtctctgttttcaaccaaatgcactaactccaaaaatgactt tcccattatgtaaaataaTTTGGTTcTATGATTAAATAgaaggtaaaaggtgaaggag a" /listShort="yjiA" /GFF_Attribute="listLong" /label="promotor_-35" upshifts complement(1291001) /Source="Nicolas_upshifts" /id="U998" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.632367632367632" /psig="0.972027972027972" /xcortree=575 /SigmaFactorBS="gtctctgttttcaaccaaatgcactaactccaaaaatgactt tcccattatgtaaaataaTTTGGTTcTATGATTAAATAgaaggtaaaaggtgaaggag a" /listShort="yjiA" /GFF_Attribute="listLong" S_feature complement(1291003..1291419) /Source="Nicolas_S_feature" /locus_tag="new_1291003_1291419_c" /HighExp="S6, S7, S8, S5, BT, C30, Pyr, G/S, C90, B36" /AntisenseName="yjiB" /AntisenseCor="-0.25565388711625397" /AntisenseRegPval="-4.7" /CDS_PredictionProba="NA" /TUshortSig="SigK" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S447" upshifts 1291171 /Source="Nicolas_upshifts" /id="U999" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.766233766233766" /psig=1 /xcortree=3183 /SigmaFactorBS="tatgcctaaggtcacgttgtgagccaaaacagcagtgcagaa tagaaaaaaattgaaagatTATGGTAAGATGAACGAAATtcgagggggaatatatgat g" /listShort="S448, yjiB, yjiC" /GFF_Attribute="listLong" misc_feature 1291172..1291191 /Source="Nicolas_upshift_promotors" /id="U999" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.766233766233766" /psig=1 /xcortree=3183 /SigmaFactorBS="tatgcctaaggtcacgttgtgagccaaaacagcagtgcagaa tagaaaaaaattgaaagatTATGGTAAGATGAACGAAATtcgagggggaatatatgat g" /listShort="S448, yjiB, yjiC" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" S_feature 1291189..1291343 /Source="Nicolas_S_feature" /locus_tag="new_1291189_1291343" /HighExp="BC, T5.0H, T4.0H, C90, Sw, T3.30H, Lbstat, Diami, dia5, S2" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.995811" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S448" CDS 1291344..1292534 /gene="cypE" /locus_tag="BSU_12210" /old_locus_tag="BSU12210" /EC_number="1.14.-.-" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:25587700" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 25587700; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="cytochrome P450 CYP109B1, monooxygenase" /protein_id="NP_389103.1" /db_xref="EnsemblGenomes-Gn:BSU12210" /db_xref="EnsemblGenomes-Tr:CAB13078" /db_xref="GOA:O34374" /db_xref="InterPro:IPR001128" /db_xref="InterPro:IPR002397" /db_xref="InterPro:IPR017972" /db_xref="InterPro:IPR036396" /db_xref="PDB:4RM4" /db_xref="SubtiList:BG13195" /db_xref="UniProtKB/Swiss-Prot:O34374" /translation="MNVLNRRQALQRALLNGKNKQDAYHPFPWYESMRKDAPVSFDEE NQVWSVFLYDDVKKVVGDKELFSSCMPQQTSSIGNSIINMDPPKHTKIRSVVNKAFTP RVMKQWEPRIQEITDELIQKFQGRSEFDLVHDFSYPLPVIVISELLGVPSAHMEQFKA WSDLLVSTPKDKSEEAEKAFLEERDKCEEELAAFFAGIIEEKRNKPEQDIISILVEAE ETGEKLSGEELIPFCTLLLVAGNETTTNLISNAMYSILETPGVYEELRSHPELMPQAV EEALRFRAPAPVLRRIAKRDTEIGGHLIKEGDMVLAFVASANRDEAKFDRPHMFDIRR HPNPHIAFGHGIHFCLGAPLARLEANIALTSLISAFPHMECVSITPIENSVIYGLKSF RVKM*" gene 1291344..1292534 /gene="cypE" /locus_tag="BSU_12210" /old_locus_tag="BSU12210" promotor_-10 complement(1291417..1291436) /Source="Nicolas_upshift_promotors" /id="U1000" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1374 /SigmaFactorBS="ggttttcttcatcaaaggaaACAGGCGCATcctttctcatcg aTTCATACCATGGAAACGGATgatacgcatcctgtttgtttttcccattgagcagcgc t" /listShort="S447, yjiA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1291419) /Source="Nicolas_upshifts" /id="U1000" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1374 /SigmaFactorBS="ggttttcttcatcaaaggaaACAGGCGCATcctttctcatcg aTTCATACCATGGAAACGGATgatacgcatcctgtttgtttttcccattgagcagcgc t" /listShort="S447, yjiA" /GFF_Attribute="listLong" promotor_-35 complement(1291450..1291459) /Source="Nicolas_upshift_promotors" /id="U1000" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1374 /SigmaFactorBS="ggttttcttcatcaaaggaaACAGGCGCATcctttctcatcg aTTCATACCATGGAAACGGATgatacgcatcctgtttgtttttcccattgagcagcgc t" /listShort="S447, yjiA" /GFF_Attribute="listLong" /label="promotor_-35" CDS 1292557..1293735 /gene="ppuG" /locus_tag="BSU_12220" /old_locus_tag="BSU12220" /EC_number="2.4.1.-" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1c: Function from experimental evidences in the studied genus; PubMedId: 24893262, 27444326; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="polyphenols TDP-rhamnosyltransferase, promiscuous" /protein_id="NP_389104.1" /db_xref="EnsemblGenomes-Gn:BSU12220" /db_xref="EnsemblGenomes-Tr:CAB13079" /db_xref="GOA:O34539" /db_xref="InterPro:IPR002213" /db_xref="InterPro:IPR006326" /db_xref="InterPro:IPR007235" /db_xref="SubtiList:BG13196" /db_xref="UniProtKB/Swiss-Prot:O34539" /translation="MKKYHISMINIPAYGHVNPTLALVEKLCEKGHRVTYATTEEFAP AVQQAGGEALIYHTSLNIDPKQIREMMEKNDAPLSLLKESLSILPQLEELYKDDQPDL IIYDFVALAGKLFAEKLNVPVIKLCSSYAQNESFQLGNEDMLKKIREAEAEFKAYLEQ EKLPAVSFEQLAVPEALNIVFMPKSFQIQHETFDDRFCFVGPSLGERKEKESLLIDKD DRPLMLISLGTAFNAWPEFYKMCIKAFRDSSWQVIMSVGKTIDPESLEDIPANFTIRQ SVPQLEVLEKADLFISHGGMNSTMEAMNAGVPLVVIPQMYEQELTANRVDELGLGVYL PKEEVTVSSLQEAVQAVSSDQELLSRVKNMQKDVKEAGGAERAAAEIEAFMKKSAVPQ *" gene 1292557..1293735 /gene="ppuG" /locus_tag="BSU_12220" /old_locus_tag="BSU12220" CDS complement(1293776..1293964) /gene="yjzI" /locus_tag="BSU_12229" /old_locus_tag="BSU12229" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences" /codon_start=1 /transl_table=11 /product="putative phage protein" /protein_id="YP_003097710.1" /db_xref="EnsemblGenomes-Gn:BSU12229" /db_xref="EnsemblGenomes-Tr:CAX52600" /db_xref="UniProtKB/Swiss-Prot:C0H3Z3" /translation="METKKEEYETKGYDTSIVYEFNEYPDARSGRCDNCDYTLFKSSV KGGKFLRECRRCGMKKNI*" gene complement(1293776..1293964) /gene="yjzI" /locus_tag="BSU_12229" /old_locus_tag="BSU12229" downshifts complement(1293792) /Source="Nicolas_upshifts" /id="D680" /incds=0 /nref=94 /ntot=231 /MaxReadThrough="-0.1433" /MaxDrop="5.1712" /score="13.0160925" /energy="-9.5" /TU="NA" /idTUdmin="U1001" /TUdmin=3 /isTUend="TRUE" promotor_-10 complement(1293990..1294009) /Source="Nicolas_upshift_promotors" /id="U1001" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.34965034965035" /psig="0.993006993006993" /xcortree=2410 /SigmaFactorBS="agataaacccaacctcctaaaatcCATTGAAtacgccggaag ctTGCTGTAAGATAAACAGCAGacacgtcttgtaacggaggatcgacatggaaaccaa a" /listShort="yjzI" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1293993) /Source="Nicolas_upshifts" /id="U1001" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.34965034965035" /psig="0.993006993006993" /xcortree=2410 /SigmaFactorBS="agataaacccaacctcctaaaatcCATTGAAtacgccggaag ctTGCTGTAAGATAAACAGCAGacacgtcttgtaacggaggatcgacatggaaaccaa a" /listShort="yjzI" /GFF_Attribute="listLong" promotor_-35 complement(1294023..1294029) /Source="Nicolas_upshift_promotors" /id="U1001" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.34965034965035" /psig="0.993006993006993" /xcortree=2410 /SigmaFactorBS="agataaacccaacctcctaaaatcCATTGAAtacgccggaag ctTGCTGTAAGATAAACAGCAGacacgtcttgtaacggaggatcgacatggaaaccaa a" /listShort="yjzI" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1294051..1294058 /Source="Nicolas_upshift_promotors" /id="U1002" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.356643356643357" /psig="0.982017982017982" /xcortree=2379 /SigmaFactorBS="tcaatggattttaggaggttgggtttaTCTTGATTtctccct tggtttgCGCCAAAATAGCTTTATTAAgcttatatacataaaaagcctatgcaaagag g" /listShort="yjjA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1294073..1294092 /Source="Nicolas_upshift_promotors" /id="U1002" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.356643356643357" /psig="0.982017982017982" /xcortree=2379 /SigmaFactorBS="tcaatggattttaggaggttgggtttaTCTTGATTtctccct tggtttgCGCCAAAATAGCTTTATTAAgcttatatacataaaaagcctatgcaaagag g" /listShort="yjjA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1294084 /Source="Nicolas_upshifts" /id="U1002" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.356643356643357" /psig="0.982017982017982" /xcortree=2379 /SigmaFactorBS="tcaatggattttaggaggttgggtttaTCTTGATTtctccct tggtttgCGCCAAAATAGCTTTATTAAgcttatatacataaaaagcctatgcaaagag g" /listShort="yjjA" /GFF_Attribute="listLong" promotor_-10 complement(1294099..1294118) /Source="Nicolas_upshift_promotors" /id="U1003" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.868131868131868" /psig="0.868131868131868" /xcortree=1376 /SigmaFactorBS="cgttttccaagtaacccttttccCATACCCGtttcctctcct cttTGCATAGGCTTTTTATGTATataagcttaataaagctattttggcgcaaaccaag g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1294103) /Source="Nicolas_upshifts" /id="U1003" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.868131868131868" /psig="0.868131868131868" /xcortree=1376 /SigmaFactorBS="cgttttccaagtaacccttttccCATACCCGtttcctctcct cttTGCATAGGCTTTTTATGTATataagcttaataaagctattttggcgcaaaccaag g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(1294133..1294140) /Source="Nicolas_upshift_promotors" /id="U1003" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.868131868131868" /psig="0.868131868131868" /xcortree=1376 /SigmaFactorBS="cgttttccaagtaacccttttccCATACCCGtttcctctcct cttTGCATAGGCTTTTTATGTATataagcttaataaagctattttggcgcaaaccaag g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" CDS 1294138..1294950 /gene="yjjA" /locus_tag="BSU_12230" /old_locus_tag="BSU12230" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative enzyme" /protein_id="NP_389105.1" /db_xref="EnsemblGenomes-Gn:BSU12230" /db_xref="EnsemblGenomes-Tr:CAB13080" /db_xref="GOA:O34394" /db_xref="InterPro:IPR003754" /db_xref="InterPro:IPR036108" /db_xref="SubtiList:BG13197" /db_xref="UniProtKB/Swiss-Prot:O34394" /translation="MGKGLLGKRVAIGGSRKTEEISTIIEKQGGIPVIRPLQGTVYLA EKQVEPDLRTFAEEKADWVIFTTGIGLETLVDMAEKIGLKDEFLQAIRQAKAACRGYK TLSALKKLGITPEASDEDGTTRGLIRSLEPHDFSGKTVMVQLHGEKAPALMAFLEEKG ASVLPILPYQHIPPEEETVERLCRELMNDEVDAVCFTTAIQVRSLFDFAKGRGYINEV KKVFEERAIAAAVGKVTAEALREEGITRLLAPEIERMGAMIVELAKYYEEKE*" gene 1294138..1294950 /gene="yjjA" /locus_tag="BSU_12230" /old_locus_tag="BSU12230" downshifts 1294929 /Source="Nicolas_upshifts" /id="D681" /incds=0 /nref=196 /ntot=254 /MaxReadThrough="3.61369" /MaxDrop="5.73094" /score="10.6328997" /energy="-14.5" /TU="U1002" /idTUdmin="U1002" /TUdmin="-22" /isTUend="TRUE" CDS complement(1294996..1295748) /gene="yjkA" /locus_tag="BSU_12240" /old_locus_tag="BSU12240" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative ABC transporter (permease)" /protein_id="NP_389106.1" /db_xref="EnsemblGenomes-Gn:BSU12240" /db_xref="EnsemblGenomes-Tr:CAB13081" /db_xref="GOA:O34684" /db_xref="InterPro:IPR005226" /db_xref="SubtiList:BG13198" /db_xref="UniProtKB/Swiss-Prot:O34684" /translation="MDYLSLSLTMIFVLIALFLSKSFKAGVEKDMIIATIRAAVQLLI IGYVLSLIFRGDHPVFILLMVLLMLAVAAQNVIKRKKNTIGSFWRVFAALAIVEIVTQ GILLSLHIIPLTARYVIPISGMVIGNSMVLSSLFLNRLNSEVGVRKEEIQLILSLGGT PKQSIQRILTSAMKMSMIPTLESQKTLGLVQLPGMMTGQILAGADPIQAVRFQLLIVF TTMASAALTCVILSVLTYPSLFTVHQQLKQNE*" gene complement(1294996..1295748) /gene="yjkA" /locus_tag="BSU_12240" /old_locus_tag="BSU12240" downshifts complement(1295005) /Source="Nicolas_upshifts" /id="D682" /incds=0 /nref=5 /ntot=153 /MaxReadThrough="0.924970000000001" /MaxDrop="3.5673" /score="13.1058081" /energy="-12.8" /TU="NA" /idTUdmin="U1001" /TUdmin="-1210" /isTUend="FALSE" CDS complement(1295748..1296500) /gene="yjkB" /locus_tag="BSU_12250" /old_locus_tag="BSU12250" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative ABC transporter (ATP-binding protein)" /protein_id="NP_389107.1" /db_xref="EnsemblGenomes-Gn:BSU12250" /db_xref="EnsemblGenomes-Tr:CAB13082" /db_xref="GOA:O34756" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR005670" /db_xref="InterPro:IPR017871" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG13199" /db_xref="UniProtKB/Swiss-Prot:O34756" /translation="MEANDQTQNIPAISFRSVRKSYKQDGQTYDVLQDVTGDIQQGAI VAVLGPSGSGKSTLLSMCNLMRTPDSGEVNIYGKEVREWNVNELRRTAALAFQSAPVL DGTVRDNLSLVQRLHQSQLYSPEKLASLAGLPPELLDRSARDLSGGQRQRLSLARTLS NPSSILLLDEITSALDPVSALEIEELIKRQHQEKKWTVMWVTHNMEQAKRIADTIWFM ADGRLLEIAETDTFFSAPQHEAAKEFLKGGTR*" gene complement(1295748..1296500) /gene="yjkB" /locus_tag="BSU_12250" /old_locus_tag="BSU12250" CDS complement(1296620..1297594) /gene="yjlA" /locus_tag="BSU_12260" /old_locus_tag="BSU12260" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 14627822, 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative permease" /protein_id="NP_389108.1" /db_xref="EnsemblGenomes-Gn:BSU12260" /db_xref="EnsemblGenomes-Tr:CAB13083" /db_xref="GOA:O34428" /db_xref="InterPro:IPR032713" /db_xref="SubtiList:BG13200" /db_xref="UniProtKB/Swiss-Prot:O34428" /translation="MKAIVIGILASLFFAVTFILNRAMELSGGSWLWSSSLRFIFMVP FLCLIVIMRGTFTPLLLEMRKKPFYWIKWSFVGFVLFYAPITFAAAYGPGWLIAGTWQ ITIVAGVLLSPLFYVKQDMPGGPQLIRQKIPLVSLGTSVIILIGAALIQLQHAESLSG RMLLFSVLPVVIAAFAYPLGNRRMLEEYGGRLDTFQRVLGMTLASLPFWLILAAYGWW SDGLPTASQTVQSFIVAVSSGIIATVLFFWATDMVRDNPQKLAAVEATQSGEVIFALL GEIVLLSGVFPSLLSFAGLFIIIAGMMLHTFASQPRKPKKKAQSNLTA*" gene complement(1296620..1297594) /gene="yjlA" /locus_tag="BSU_12260" /old_locus_tag="BSU12260" downshifts complement(1296655) /Source="Nicolas_upshifts" /id="D683" /incds=0 /nref=1 /ntot=95 /MaxReadThrough="1.84381" /MaxDrop="2.54799" /score="4.80318278" /energy="-14.5" /TU="NA" /idTUdmin="U1004" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(1297615..1297634) /Source="Nicolas_upshift_promotors" /id="U1004" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.451548451548452" /psig="0.997002997002997" /xcortree=2386 /SigmaFactorBS="tccacatatagcggttcgccaaacatgatgtttttctcatga ttcCATTGATCtgcatgataccgaaTAGTATAGTATAAAAAAATAatgccagaatgag g" /listShort="yjlA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1297641) /Source="Nicolas_upshifts" /id="U1004" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.451548451548452" /psig="0.997002997002997" /xcortree=2386 /SigmaFactorBS="tccacatatagcggttcgccaaacatgatgtttttctcatga ttcCATTGATCtgcatgataccgaaTAGTATAGTATAAAAAAATAatgccagaatgag g" /listShort="yjlA" /GFF_Attribute="listLong" S_feature complement(1297643..1300149) /Source="Nicolas_S_feature" /locus_tag="new_1297643_1300149_c" /HighExp="Lbstat, S2, M0t90, nit, BT, M40t90, ferm, BC, C30, Gly" /AntisenseName="ndh" /AntisenseCor="-0.74506751931257098" /AntisenseRegPval="-48.1" /CDS_PredictionProba="NA" /TUshortSig="SigH" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S449" promotor_-35 complement(1297649..1297656) /Source="Nicolas_upshift_promotors" /id="U1004" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.451548451548452" /psig="0.997002997002997" /xcortree=2386 /SigmaFactorBS="tccacatatagcggttcgccaaacatgatgtttttctcatga ttcCATTGATCtgcatgataccgaaTAGTATAGTATAAAAAAATAatgccagaatgag g" /listShort="yjlA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1297677..1297683 /Source="Nicolas_upshift_promotors" /id="U1005" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=269 /SigmaFactorBS="atcatgcagatcaatggaatcatgagaaaaacatcaTGTTTG GcgaaccgctatatgTGGAAGACAAAAAAGGGAGgtgaaattgatggaaagagagaca c" /listShort="yjlB, S450, S451, rex, ndh" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1297698..1297716 /Source="Nicolas_upshift_promotors" /id="U1005" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=269 /SigmaFactorBS="atcatgcagatcaatggaatcatgagaaaaacatcaTGTTTG GcgaaccgctatatgTGGAAGACAAAAAAGGGAGgtgaaattgatggaaagagagaca c" /listShort="yjlB, S450, S451, rex, ndh" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1297701 /Source="Nicolas_upshifts" /id="U1005" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=269 /SigmaFactorBS="atcatgcagatcaatggaatcatgagaaaaacatcaTGTTTG GcgaaccgctatatgTGGAAGACAAAAAAGGGAGgtgaaattgatggaaagagagaca c" /listShort="yjlB, S450, S451, rex, ndh" /GFF_Attribute="listLong" CDS 1297726..1298223 /gene="yjlB" /locus_tag="BSU_12270" /old_locus_tag="BSU12270" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 10704478" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein; cupin family" /protein_id="NP_389109.1" /db_xref="EnsemblGenomes-Gn:BSU12270" /db_xref="EnsemblGenomes-Tr:CAB13084" /db_xref="GOA:O34612" /db_xref="InterPro:IPR006045" /db_xref="InterPro:IPR011051" /db_xref="InterPro:IPR014500" /db_xref="InterPro:IPR014710" /db_xref="SubtiList:BG13201" /db_xref="UniProtKB/Swiss-Prot:O34612" /translation="MERETQTYFFPDDGRIPNHPDFPLVVYQNALKDTGLAERIVTRH GWSNSWSGSVFPYHHYHSNTHEVLIALRREAVIQFGGEKGAAIPFKSGDAVVIPAGVG HKKLSSSPDFTVLGAYPGGVQYDMKTGKPNEREEAVKQIKQAALPANDPITGKREPLL EIWVK*" gene 1297726..1298223 /gene="yjlB" /locus_tag="BSU_12270" /old_locus_tag="BSU12270" S_feature 1298224..1298337 /Source="Nicolas_S_feature" /locus_tag="new_1298224_1298337" /HighExp="Etha, M9-stat, B60, Salt, Gly, LPhT, Heat, Sw, HiTm, B36" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigB" /TUshortPSig="0.998" /TUlongSig="NA" /TUlongPSig="NA" /label="S450" promotor_-35 1298317..1298321 /Source="Nicolas_upshift_promotors" /id="U1006" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.618381618381618" /psig=1 /xcortree=2641 /SigmaFactorBS="agctccatataaattaatttcataatcgaagcaattcaCGTT CaaattttgttcaaaaAGTGTTATCATATAGAAGGTaatcgaattggagttttttgtg t" /listShort="S451, rex, ndh" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1298337..1298356 /Source="Nicolas_upshift_promotors" /id="U1006" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.618381618381618" /psig=1 /xcortree=2641 /SigmaFactorBS="agctccatataaattaatttcataatcgaagcaattcaCGTT CaaattttgttcaaaaAGTGTTATCATATAGAAGGTaatcgaattggagttttttgtg t" /listShort="S451, rex, ndh" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 1298339..1298611 /Source="Nicolas_S_feature" /locus_tag="new_1298339_1298611" /HighExp="LBGtran, dia5, Lbexp, LBGexp, dia0, HPh, aero, LPh, BMM, MG 25" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigB" /TUshortPSig="1, 0.998" /TUlongSig="NA" /TUlongPSig="NA" /label="S451" upshifts 1298339 /Source="Nicolas_upshifts" /id="U1006" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.618381618381618" /psig=1 /xcortree=2641 /SigmaFactorBS="agctccatataaattaatttcataatcgaagcaattcaCGTT CaaattttgttcaaaaAGTGTTATCATATAGAAGGTaatcgaattggagttttttgtg t" /listShort="S451, rex, ndh" /GFF_Attribute="listLong" CDS 1298612..1299034 /gene="yjlC" /locus_tag="BSU_12280" /old_locus_tag="BSU12280" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 16513748, 17015645, 22720735" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_389110.1" /db_xref="EnsemblGenomes-Gn:BSU12280" /db_xref="EnsemblGenomes-Tr:CAB13085" /db_xref="InterPro:IPR012440" /db_xref="SubtiList:BG13202" /db_xref="UniProtKB/Swiss-Prot:O34633" /translation="MPETIDQTNASVSQSQQDLIDQLLKPEVQESLTVLVDQLPKLTE LVNILTKSYDFAQSVATDEVLKSDTVGAITEILEPVKETAKEVAATAIEAKDRAEASN ETIGLFGLLRMLKDPQAQKLFRFANSYLEVMNERENQK*" gene 1298612..1299034 /gene="yjlC" /locus_tag="BSU_12280" /old_locus_tag="BSU12280" CDS 1299074..1300252 /gene="ndh" /locus_tag="BSU_12290" /old_locus_tag="BSU12290" /EC_number="1.6.99.-" /function="16.10: Respire" /experiment="publication(s) with functional evidences, PMID:6816592, 16513748, 17015645, 22720735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 6816592, 16513748, 17015645, 22720735; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="NADH dehydrogenase" /protein_id="NP_389111.1" /db_xref="EnsemblGenomes-Gn:BSU12290" /db_xref="EnsemblGenomes-Tr:CAB13086" /db_xref="GOA:P80861" /db_xref="InterPro:IPR023753" /db_xref="InterPro:IPR036188" /db_xref="SubtiList:BG13203" /db_xref="UniProtKB/Swiss-Prot:P80861" /translation="MSKHIVILGAGYGGVLSALTVRKHYTKEQARVTVVNKYPTHQII TELHRLAAGNVSEKAVAMPLEKLFKGKDIDLKIAEVSSFSVDKKEVALADGSTLTYDA LVVGLGSVTAYFGIPGLEENSMVLKSAADANKVFQHVEDRVREYSKTKNEADATILIG GGGLTGVELVGELADIMPNLAKKYGVDHKEIKLKLVEAGPKILPVLPDDLIERATASL EKRGVEFLTGLPVTNVEGNVIDLKDGSKVVANTFVWTGGVQGNPLVGESGLEVNRGRA TVNDFLQSTSHEDVFVAGDSAVYFGPDGRPYPPTAQIAWQMGELIGYNLFAYLEGKTL ETFKPVNSGTLASLGRKDAVAIIGANSTPLKGLPASLMKEASNVRYLTHIKGLFSLAY *" gene 1299074..1300252 /gene="ndh" /locus_tag="BSU_12290" /old_locus_tag="BSU12290" promotor_no_box 1300083..1300183 /Source="Nicolas_upshift_promotors" /id="U1007" /multdbtbs="-" /comp="M21" /sig="Sig-" /pcomp="0.59040959040959" /psig="0.015984015984016" /xcortree=1732 /SigmaFactorBS="tcaagccagtaaactctggtacacttgcaagccttggacgca aagacgcggttgccatcattggtgctaattctacaccgcttaaaggtcttcctgcttc c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_no_box" promotor_-10 complement(1300141..1300159) /Source="Nicolas_upshift_promotors" /id="U1008" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp=1 /psig=1 /xcortree=506 /SigmaFactorBS="cgtacattacttgcttctttcatcaaggaaGCAGGAAGAcct ttaagcggTGTAGAATTAGCACCAATGatggcaaccgcgtctttgcgtccaaggcttg c" /listShort="S449, yjlA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1300143 /Source="Nicolas_upshifts" /id="U1007" /multdbtbs="-" /comp="M21" /sig="Sig-" /pcomp="0.59040959040959" /psig="0.015984015984016" /xcortree=1732 /SigmaFactorBS="tcaagccagtaaactctggtacacttgcaagccttggacgca aagacgcggttgccatcattggtgctaattctacaccgcttaaaggtcttcctgcttc c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" upshifts complement(1300149) /Source="Nicolas_upshifts" /id="U1008" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp=1 /psig=1 /xcortree=506 /SigmaFactorBS="cgtacattacttgcttctttcatcaaggaaGCAGGAAGAcct ttaagcggTGTAGAATTAGCACCAATGatggcaaccgcgtctttgcgtccaaggcttg c" /listShort="S449, yjlA" /GFF_Attribute="listLong" promotor_-35 complement(1300171..1300179) /Source="Nicolas_upshift_promotors" /id="U1008" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp=1 /psig=1 /xcortree=506 /SigmaFactorBS="cgtacattacttgcttctttcatcaaggaaGCAGGAAGAcct ttaagcggTGTAGAATTAGCACCAATGatggcaaccgcgtctttgcgtccaaggcttg c" /listShort="S449, yjlA" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 1300251 /Source="Nicolas_upshifts" /id="D684" /incds=0 /nref=220 /ntot=278 /MaxReadThrough="2.01042" /MaxDrop="8.69373" /score="30.6421047" /energy="-23.1" /TU="NA" /idTUdmin="U1005" /TUdmin="-2" /isTUend="TRUE" promotor_-35 1300360..1300367 /Source="Nicolas_upshift_promotors" /id="U1009" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.694305694305694" /psig="0.935064935064935" /xcortree=1573 /SigmaFactorBS="ttttcaaaaaagaGATTGATCccaaaggaatataaAGGTAAA ATAAAAACAAATCaaaatgttaacgttaacattttgaaatagaatgaaagacggtgag g" /listShort="uxaC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1300382..1300401 /Source="Nicolas_upshift_promotors" /id="U1009" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.694305694305694" /psig="0.935064935064935" /xcortree=1573 /SigmaFactorBS="ttttcaaaaaagaGATTGATCccaaaggaatataaAGGTAAA ATAAAAACAAATCaaaatgttaacgttaacattttgaaatagaatgaaagacggtgag g" /listShort="uxaC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1300407 /Source="Nicolas_upshifts" /id="U1009" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.694305694305694" /psig="0.935064935064935" /xcortree=1573 /SigmaFactorBS="ttttcaaaaaagaGATTGATCccaaaggaatataaAGGTAAA ATAAAAACAAATCaaaatgttaacgttaacattttgaaatagaatgaaagacggtgag g" /listShort="uxaC" /GFF_Attribute="listLong" CDS 1300450..1301871 /gene="uxaC" /locus_tag="BSU_12300" /old_locus_tag="BSU12300" /EC_number="5.3.1.12" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 9579062, 9882655; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="galacturonate isomerase" /protein_id="NP_389112.1" /db_xref="EnsemblGenomes-Gn:BSU12300" /db_xref="EnsemblGenomes-Tr:CAB13087" /db_xref="GOA:O34808" /db_xref="InterPro:IPR003766" /db_xref="InterPro:IPR032466" /db_xref="SubtiList:BG13204" /db_xref="UniProtKB/Swiss-Prot:O34808" /translation="MEPFMGKNFLLKNETAVSLYHNYAKDMPIIDYHCHLSPKEIYEN KTFQNITEAWLYGDHYKWRIMRANGIEETYITGDAPDEEKFMAWAKTVPMAIGNPLYN WTHLELQRFFGIYEILNEKSGSAIWKQTNKLLKGEGFGARDLIVKSNVKVVCTTDDPV DSLEYHLLLKEDKDFPVSVLPGFRPDKGLEINREGFPEWVQALEDAAAISITTYDEFL KALEKRVRFFHSAGGRVSDHAIDTMVFAETTKEEAGRIFSDRLQGTEVSCEDEKKFKT YTLQFLCGLYAELDWAMQFHINALRNTNTKMMKRLGPDTGYDSMNDEEIAKPLYKLLN SVEMKNQLPKTILYSLNPNDNYVIASMINSFQDGITPGKIQFGTAWWFNDTKDGMLDQ MKALSNVGLFSRFIGMLTDSRSFLSYTRHEYFRRIVCNLIGEWVENGEVPRDMELLGS IVQGICYDNAKHYFQFQEEKANV*" gene 1300450..1301871 /gene="uxaC" /locus_tag="BSU_12300" /old_locus_tag="BSU12300" CDS 1301939..1303318 /gene="exuM" /locus_tag="BSU_12310" /old_locus_tag="BSU12310" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 9882655, 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative Na+:altronate/mannonate symporter" /protein_id="NP_389113.1" /db_xref="EnsemblGenomes-Gn:BSU12310" /db_xref="EnsemblGenomes-Tr:CAB13088" /db_xref="GOA:O34961" /db_xref="InterPro:IPR001927" /db_xref="InterPro:IPR018043" /db_xref="InterPro:IPR020846" /db_xref="InterPro:IPR036259" /db_xref="SubtiList:BG13205" /db_xref="UniProtKB/Swiss-Prot:O34961" /translation="MRTELANKVVSVETEKRLSLKEKMSYGFGDFGNGFMFDLGQIYL LKYFTDVAGIPAAMAGGIFLVSKLFAAITDPIVGSSIDYRKNIGKRGKFRPYLLIGSI VLAVLTVLIFLSPNVSTTGKLIYAYASYMIWGIGYSFVNIPYGSLGAAMTQNSEDRTS ISTFRQIGSLGALFITSVAVMPLLVKFDNPKVGYPVVMGLFAALGVFWFYICYRNCKE RIIISEAPKEKLTLSSVVKTFITNKPLLTLVLMTIFSISAYNIKSAMLVYFAQYNLGN VELMAYMNFIIIGSSFLGVVFLPKLVKMFGKKRTAMIGFGISVAADLINFMLPSNVYV FTILASIAFIGISIPNGITWALVSDIIDYGEWKSGERKEATTYSLFNFSRKLAQSLSG FLSGIGLGIIGYVPNAVQTAQALIGIKALLLLYPAIALALAMFIIGFLYKLTDQQHAQ IVQDLHQKS*" gene 1301939..1303318 /gene="exuM" /locus_tag="BSU_12310" /old_locus_tag="BSU12310" promotor_-10 complement(1302458..1302477) /Source="Nicolas_upshift_promotors" /id="U1010" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.988011988011988" /psig="0.999000999001" /xcortree=2077 /SigmaFactorBS="cgggtagccgaccttcggattatcaAACTTGACgagcagcgg catcACGGCCACACTTGTGATAAAcaaggcgccaagtgatccgatttggcggaacgtc g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1302463) /Source="Nicolas_upshifts" /id="U1010" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.988011988011988" /psig="0.999000999001" /xcortree=2077 /SigmaFactorBS="cgggtagccgaccttcggattatcaAACTTGACgagcagcgg catcACGGCCACACTTGTGATAAAcaaggcgccaagtgatccgatttggcggaacgtc g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(1302491..1302498) /Source="Nicolas_upshift_promotors" /id="U1010" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.988011988011988" /psig="0.999000999001" /xcortree=2077 /SigmaFactorBS="cgggtagccgaccttcggattatcaAACTTGACgagcagcgg catcACGGCCACACTTGTGATAAAcaaggcgccaagtgatccgatttggcggaacgtc g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 1303343 /Source="Nicolas_upshifts" /id="U1011" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp="0.926073926073926" /psig="0.926073926073926" /xcortree=1048 /SigmaFactorBS="gctcagatcgttcaggatcttcatcaaaagagctgacaatat aatataaagaatatttaaaataatttgtAAATAAAAtgtgtttgtaggggtttcgctt g" /listShort="S452, yjmC, yjmD, uxuA, uxuB, exuT, exuR" /GFF_Attribute="listLong" misc_feature 1303353..1303360 /Source="Nicolas_upshift_promotors" /id="U1011" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp="0.926073926073926" /psig="0.926073926073926" /xcortree=1048 /SigmaFactorBS="gctcagatcgttcaggatcttcatcaaaagagctgacaatat aatataaagaatatttaaaataatttgtAAATAAAAtgtgtttgtaggggtttcgctt g" /listShort="S452, yjmC, yjmD, uxuA, uxuB, exuT, exuR" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" S_feature 1303355..1303422 /Source="Nicolas_S_feature" /locus_tag="new_1303355_1303422" /HighExp="S4, S5, S6, S3, S8, S7, T5.0H, T4.0H, T3.30H, M9-stat" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigEF" /TUshortPSig="0.926" /TUlongSig="NA" /TUlongPSig="NA" /label="S452" CDS 1303423..1304436 /gene="yjmC" /locus_tag="BSU_12320" /old_locus_tag="BSU12320" /EC_number="1.1.1.-" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 9579062, 9882655, 16788182; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative oxidoreductase" /protein_id="NP_389114.1" /db_xref="EnsemblGenomes-Gn:BSU12320" /db_xref="EnsemblGenomes-Tr:CAB13089" /db_xref="GOA:O34736" /db_xref="InterPro:IPR003767" /db_xref="InterPro:IPR036111" /db_xref="SubtiList:BG13206" /db_xref="UniProtKB/Swiss-Prot:O34736" /translation="MKTITIAAEEAKELVWQKLDGAGLNERDAEKVADVLVHADLRNV HSHGVLHTEHYVNRLLAGGINPGAQPVFKETGPVTGVLDGDDGFGHVNCDMAMDHAID MAKKKGVGMVTAVNSSHCGALSYFVQKAADEKLIGMAMTHTDSIVVPFGGRTPILGTN PIAYGVPAKHKKPFILDMATSKVAFGKILQAREEGKEIPEGWGVDENGEAVTDPDKVV SLSTFGGPKGYGLSIVVDVFSGLLAGAAFGPHIAKMYNGLDQKRKLGHYVCAINPSFF TDWDTFLEQMDAMIDELQQSPPAVGFERVYVPGEIEQLHEERNKKNGISIARSVYEFL KSR*" gene 1303423..1304436 /gene="yjmC" /locus_tag="BSU_12320" /old_locus_tag="BSU12320" CDS 1304442..1305461 /gene="yjmD" /locus_tag="BSU_12330" /old_locus_tag="BSU12330" /EC_number="1.1.1.-" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 9579062, 9882655; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative oxidoreductase" /protein_id="NP_389115.1" /db_xref="EnsemblGenomes-Gn:BSU12330" /db_xref="EnsemblGenomes-Tr:CAB13090" /db_xref="GOA:O35045" /db_xref="InterPro:IPR002328" /db_xref="InterPro:IPR011032" /db_xref="InterPro:IPR013149" /db_xref="InterPro:IPR013154" /db_xref="InterPro:IPR020843" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG13207" /db_xref="UniProtKB/Swiss-Prot:O35045" /translation="MKAVQVRKAYDLVTAEVKKPVLSKDDEVLVKVKRVGICGSDMHI YHGTNPLATLPRVIGHEVTGQVEAVGANVQSLKPGDHVVIEPISYCGSCYACRKGRPN VCAKLSVFGVHEDGGMREYIVLPERQLHAVSKDLPWEEAVMAEPYTIGAQAVWRGQVE KGDTVLIQGAGPIGICVLKMAKLAGAAVMMTDLNNERLAFAKENGADAVVNVQAEHVA ERVLEWTGNEGANVVIDAVCLPETFALSIEAVSPAGHVVVLGFDERAAQISQLPITKK EVTITGSRLQTNQFPKVVELLNGGRLMHNGLVTHTFSVDDVHHAFQFIKEHPDQVRKA VITFD*" gene 1304442..1305461 /gene="yjmD" /locus_tag="BSU_12330" /old_locus_tag="BSU12330" CDS 1305486..1306565 /gene="uxuA" /locus_tag="BSU_12340" /old_locus_tag="BSU12340" /EC_number="4.2.1.8" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1c: Function from experimental evidences in the studied genus; PubMedId: 9579062, 9882655, 10368143, 25145794; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="D-mannonate dehydratase" /protein_id="NP_389116.1" /db_xref="EnsemblGenomes-Gn:BSU12340" /db_xref="EnsemblGenomes-Tr:CAB13091" /db_xref="GOA:O34346" /db_xref="InterPro:IPR004628" /db_xref="InterPro:IPR036237" /db_xref="SubtiList:BG13208" /db_xref="UniProtKB/Swiss-Prot:O34346" /translation="MNMTFRWYGRGNDTVTLEYVKQIPGVKGIVWALHQKPVGDVWEK EEIRAETEYIQSYGFHAEVVESVNVHEAIKLGNEERGRYIENYKQTIRNLAGFGVKVI CYNFMPVFDWTRTDMFRPLEDGSTALFFEKAKVESLDPQELIRTVEEASDMTLPGWEP EKLARIKELFAAYRTVDEEKLWDNLSFFLQEILPVAEAYGVQMAIHPDDPPWPIFGLP RIITGEASYKKLRAISDSPSNCITLCTGSMGANPANDMVEIAKTYAGIAPFSHIRNVK IYENGDFIETSHLTKDGSINIQGVMEELHKQDYEGYVRPDHGRHLWGEQCRPGYGLYD RALGIMYLNGLWDAYEAMAKKEVGI*" gene 1305486..1306565 /gene="uxuA" /locus_tag="BSU_12340" /old_locus_tag="BSU12340" CDS 1306562..1307398 /gene="uxuB" /locus_tag="BSU_12350" /old_locus_tag="BSU12350" /EC_number="1.1.1.57" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 9579062, 9882655, 10368143; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="fructuronate reductase" /protein_id="NP_389117.1" /db_xref="EnsemblGenomes-Gn:BSU12350" /db_xref="EnsemblGenomes-Tr:CAB13092" /db_xref="GOA:O34896" /db_xref="InterPro:IPR002347" /db_xref="InterPro:IPR020904" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG13209" /db_xref="UniProtKB/Swiss-Prot:O34896" /translation="MIPLHENLAGKTAVITGGSGVLCSAMARELARHGMKVAILNRTA EKGQAVVKEITAAGGTACAVAADVLDRMSLERAKEDILGQFGAVDLLINGAGGNHPDA ITDVETYEEAGEGQSFFDMDERGFLTVFSTNFTGAFLASQVFGKELLKADSPAIINLS SMSAYSPMTKVPAYSAAKASINNFTMWMAVHFAETGLRVNAIAPGFFLTKQNHDLLIN QDGTFTSRSHKIIAGTPMKRFGKPEDLLGTLLWLADESYSGFVTGITVPVDGGFMAYS GV*" gene 1306562..1307398 /gene="uxuB" /locus_tag="BSU_12350" /old_locus_tag="BSU12350" CDS 1307446..1308714 /gene="exuT" /locus_tag="BSU_12360" /old_locus_tag="BSU12360" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 8320243, 9579062, 9882655, 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="hexuronate transporter" /protein_id="NP_389118.1" /db_xref="EnsemblGenomes-Gn:BSU12360" /db_xref="EnsemblGenomes-Tr:CAB13093" /db_xref="GOA:O34456" /db_xref="InterPro:IPR000849" /db_xref="InterPro:IPR004744" /db_xref="InterPro:IPR011701" /db_xref="InterPro:IPR020846" /db_xref="InterPro:IPR036259" /db_xref="SubtiList:BG13210" /db_xref="UniProtKB/Swiss-Prot:O34456" /translation="MFSKDKLPVILFLFLAGVINYLDRSALSIAAPFIQDDLTLSATQ MGLIFSSFSIGYAIFNFLGGVASDRYGAKLTLFVAMVVWSLFSGAVALAFGFVSLLII RILFGMGEGPLSATINKMVNNWFPPTQRASVIGVTNSGTPLGGAISGPIVGMIAVAFS WKVSFVLIMIIGLIWAVLWFKFVKEKPQETIKEAPAIKAETSPGEKIPLTFYLKQKTV LFTAFAFFAYNYILFFFLTWFPSYLVDERGLSVESMSVITVIPWILGFIGLAAGGFVS DYVYKKTARKGVLFSRKVVLVTCLFSSAVLIGFAGLVATTAGAVTLVALSVFFLYLTG AIYWAVIQDVVDQNNVGSVGGFMHFLANTAGIIGPALTGFIVDQTGTFSGAFLLAGGL AVFASLAVIRFVRPIIGKPAGTEAENPVSY*" gene 1307446..1308714 /gene="exuT" /locus_tag="BSU_12360" /old_locus_tag="BSU12360" promotor_-35 1308658..1308661 /Source="Nicolas_upshift_promotors" /id="U1012" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.637362637362637" /psig="0.005994005994006" /xcortree=1486 /SigmaFactorBS="ctggctgtcttcgcttcacttgctgtgattcgttttgtcCGT CcaatcattggtaagcCAGCGggaacagaagctgagaatcctgtgtcttattaatctg g" /listShort="exuR" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1308677..1308681 /Source="Nicolas_upshift_promotors" /id="U1012" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.637362637362637" /psig="0.005994005994006" /xcortree=1486 /SigmaFactorBS="ctggctgtcttcgcttcacttgctgtgattcgttttgtcCGT CcaatcattggtaagcCAGCGggaacagaagctgagaatcctgtgtcttattaatctg g" /listShort="exuR" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1308679 /Source="Nicolas_upshifts" /id="U1012" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.637362637362637" /psig="0.005994005994006" /xcortree=1486 /SigmaFactorBS="ctggctgtcttcgcttcacttgctgtgattcgttttgtcCGT CcaatcattggtaagcCAGCGggaacagaagctgagaatcctgtgtcttattaatctg g" /listShort="exuR" /GFF_Attribute="listLong" misc_feature 1308747..1308766 /Source="Nicolas_upshift_promotors" /id="U1013" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.966033966033966" /psig=1 /xcortree=3107 /SigmaFactorBS="agaagctgagaatcctgtgtcttattaatctggaaatatagt gggagaggcggtatgtttGATGATACAATATACAGTAAataatcgcagccggtatgat a" /listShort="exuR" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 1308747 /Source="Nicolas_upshifts" /id="U1013" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.966033966033966" /psig=1 /xcortree=3107 /SigmaFactorBS="agaagctgagaatcctgtgtcttattaatctggaaatatagt gggagaggcggtatgtttGATGATACAATATACAGTAAataatcgcagccggtatgat a" /listShort="exuR" /GFF_Attribute="listLong" CDS 1308802..1309803 /gene="exuR" /locus_tag="BSU_12370" /old_locus_tag="BSU12370" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:9579062, 9882655" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9579062, 9882655; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator (LacI family)" /protein_id="NP_389119.1" /db_xref="EnsemblGenomes-Gn:BSU12370" /db_xref="EnsemblGenomes-Tr:CAB13094" /db_xref="GOA:Q9JMQ1" /db_xref="InterPro:IPR000843" /db_xref="InterPro:IPR010982" /db_xref="InterPro:IPR028082" /db_xref="SubtiList:BG13211" /db_xref="UniProtKB/Swiss-Prot:Q9JMQ1" /translation="MVTIKDIAKLANVSHTTVSRALNNSPYIKEHTKKKILELAEQLN YTPNVNAKSLAMQKSHTIGLFFTSITNGTSHSFFADTIKGVNQAISEDYNLYVRGIDD LKNYDSVTPMRYDGIILMSQSDIDNSFIYHIREKNIPLVVLNRDIDDRTITNILSNDK EGSQEAVEYFIQSGHQDIAIIEGIEGFKSSQQRKEGYLSALIQHHIPIKHEYSVKGQY DMESGFQAMERLLALPNPPTAVFCSNDDMAIGAMNAIFAKGLRVPDDISVIGFDDIGF SQYITPRLSTVKRPVEKISVLGAQKLLSLISEPETKAEKILENTEFMVRDSVRRLTT* " gene 1308802..1309803 /gene="exuR" /locus_tag="BSU_12370" /old_locus_tag="BSU12370" promotor_no_box complement(1309485..1309585) /Source="Nicolas_upshift_promotors" /id="U1014" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.915084915084915" /psig="0.024975024975025" /xcortree=19 /SigmaFactorBS="cgcgcaggccctttgcgaatatcgcattcatcgctccgattg ccatgtcatcattcgaacaaaaaacagcggttggaggattcggcagtgccagcagccg c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_no_box" upshifts complement(1309525) /Source="Nicolas_upshifts" /id="U1014" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.915084915084915" /psig="0.024975024975025" /xcortree=19 /SigmaFactorBS="cgcgcaggccctttgcgaatatcgcattcatcgctccgattg ccatgtcatcattcgaacaaaaaacagcggttggaggattcggcagtgccagcagccg c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" downshifts 1309779 /Source="Nicolas_upshifts" /id="D685" /incds=0 /nref=2 /ntot=132 /MaxReadThrough="2.47166" /MaxDrop="3.11543" /score="12.2153519" /energy="-7.4" /TU="NA" /idTUdmin="U1011" /TUdmin=0 /isTUend="TRUE" CDS 1309880..1311322 /gene="uxaB" /locus_tag="BSU_12380" /old_locus_tag="BSU12380" /EC_number="1.1.1.58" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 9579062, 9882655; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="tagaturonate reductase (altronate oxidoreductase)" /protein_id="NP_389120.1" /db_xref="EnsemblGenomes-Gn:BSU12380" /db_xref="EnsemblGenomes-Tr:CAB13095" /db_xref="GOA:O34354" /db_xref="InterPro:IPR000669" /db_xref="InterPro:IPR008927" /db_xref="InterPro:IPR013118" /db_xref="InterPro:IPR013131" /db_xref="InterPro:IPR013328" /db_xref="InterPro:IPR023668" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG13212" /db_xref="UniProtKB/Swiss-Prot:O34354" /translation="MQKLNKNVYDHYTQYPEKILQFGEGNFLRGFIDWQIDQLNQHTD FNGSVAVVQPRGSEKIKRLNEQDGLYTLFLQGMKDGEAVNEHMIINSISRGIDLFSDY EAYKELASSERLRFIISNTTEAGIVCDEKDRLEDRPQKTFPGKLTAFLYFRYQAFKGD QTKGCVLIPCELIENNGEKLRETVLHYAHLWKLEEGFTQWIHEANTFCNSLVDRIVPG FPVDSIDEITADLGYQDDLIVVGEQYYLWVIEGPDWIGKELPFAAAGLHTKIVSDLTP YRTKKVRILNGAHTAMTPVALLYGLKTVRDAVEHPEVGRFIRELIDDEILPVLKMEGL SQYADDVLNRFKNPYIKHYLESIALNAISKFKTRNLPTLKEYAEQKGQLPERLVFSFS ALLYFYHDNETLQDDPAVLQFFKEVWCQEDGDMLRIASRVLGEQRLWGADLNEIPKLT DRVAVYLNHIHELGMQRALEQYCIQGGEVR*" gene 1309880..1311322 /gene="uxaB" /locus_tag="BSU_12380" /old_locus_tag="BSU12380" CDS 1311319..1312812 /gene="uxaA" /locus_tag="BSU_12390" /old_locus_tag="BSU12390" /EC_number="4.2.1.7" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 9579062, 9882655; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="altronate dehydratase" /protein_id="NP_389121.2" /db_xref="EnsemblGenomes-Gn:BSU12390" /db_xref="EnsemblGenomes-Tr:CAB13096" /db_xref="GOA:O34673" /db_xref="InterPro:IPR007392" /db_xref="InterPro:IPR013974" /db_xref="SubtiList:BG13213" /db_xref="UniProtKB/Swiss-Prot:O34673" /translation="MKSFIKIHKQDNVLLALRDIQKGERLHAYGVSIEVKDDIKRGHK IALQSIKENDSIVKYGFPIGHASQDISIGEHIHVHNTKTNLSDIQLYSYTPRFDENPY SNENRTFKGFRRENGDAGVRNELWIVPTVGCVNGIAEKMLQRFVRETGDIAPFDNVLV LKHQYGCSQLGDDHENTKQILLNAIRHPNAGGVLVLGLGCENNELARMKEALQDVNLK RVKFLESQSVTDEMEAGVALLKEIHEAAKGDKREDIPLSELKIGLKCGGSDGFSGITA NPLLGRFSDYLIAQGGSTVLTEVPEMFGAETILMQRAANEEVFHKIVDLINDFKQYFI KHDQPVYENPSPGNKAGGISTLEDKSLGCTQKAGISPVTDVLKYGEVLKTKGLTLLSA PGNDLIASSALAAAGCQIVLFTTGRGTPFGTFVPTVKVATNTELYEAKPHWIDFNAGL LAEDDVHEEYVLREFIHYMIEVASGQLVNHEKNDFKELAIFKSGVTL*" gene 1311319..1312812 /gene="uxaA" /locus_tag="BSU_12390" /old_locus_tag="BSU12390" CDS complement(1312851..1313615) /gene="yjnA" /locus_tag="BSU_12400" /old_locus_tag="BSU12400" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406, 16885442; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative permease" /protein_id="NP_389122.1" /db_xref="EnsemblGenomes-Gn:BSU12400" /db_xref="EnsemblGenomes-Tr:CAB13097" /db_xref="GOA:O34578" /db_xref="InterPro:IPR002781" /db_xref="SubtiList:BG13214" /db_xref="UniProtKB/Swiss-Prot:O34578" /translation="MSVSIILMGLFVGALVGLTGVGGAALLTPLLIVLGINPSIAVGT DLVYNSITKLFGVASHWRQKTINFKLVKYLAIGSIPSASLAIGILHLFPAFHQHQEEI IKHALGYVLTLVAISIIVRLFLDRKLRPNRWQLMPLENKRALTILIGVVFGFIVGLTS IGSGSLFAIAMIYLFNMKASQIVGTDIAHAFLLVTAAGILNASFGSVDYMLAANLLLG SIPGVLIGSHLSPRFSPRPLQFIMASIILVSGLKLI*" gene complement(1312851..1313615) /gene="yjnA" /locus_tag="BSU_12400" /old_locus_tag="BSU12400" downshifts complement(1312870) /Source="Nicolas_upshifts" /id="D686" /incds=0 /nref=96 /ntot=170 /MaxReadThrough="1.34004" /MaxDrop="4.60564" /score="6.47747687" /energy="-11.3" /TU="NA" /idTUdmin="U1015" /TUdmin="-1" /isTUend="TRUE" promotor_-10 complement(1313644..1313663) /Source="Nicolas_upshift_promotors" /id="U1015" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.378621378621379" /psig="0.995004995004995" /xcortree=1735 /SigmaFactorBS="aatttcaagcaactaacgtgcaaaaattcaaaaaatttAATT GATtaacgcgtcctaaTCATATATAATCTGATAAAAatagtcgggttttcaggaggcc t" /listShort="yjnA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1313661) /Source="Nicolas_upshifts" /id="U1015" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.378621378621379" /psig="0.995004995004995" /xcortree=1735 /SigmaFactorBS="aatttcaagcaactaacgtgcaaaaattcaaaaaatttAATT GATtaacgcgtcctaaTCATATATAATCTGATAAAAatagtcgggttttcaggaggcc t" /listShort="yjnA" /GFF_Attribute="listLong" S_feature complement(1313663..1313744) /Source="Nicolas_S_feature" /locus_tag="new_1313663_1313744_c" /HighExp="S6, S8, S7, S5, BT, G/S, B36, Pyr, B60, nit" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigK" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S453" promotor_-35 complement(1313677..1313683) /Source="Nicolas_upshift_promotors" /id="U1015" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.378621378621379" /psig="0.995004995004995" /xcortree=1735 /SigmaFactorBS="aatttcaagcaactaacgtgcaaaaattcaaaaaatttAATT GATtaacgcgtcctaaTCATATATAATCTGATAAAAatagtcgggttttcaggaggcc t" /listShort="yjnA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(1313727..1313746) /Source="Nicolas_upshift_promotors" /id="U1016" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1284 /SigmaFactorBS="cttttttttgcgcctttagtacttctcgatttcgtCCAGACA CTCattatagggcaaaTGAATAGAGATATTGAGCATaccaaaatttcaagcaactaac g" /listShort="S453, yjnA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1313744) /Source="Nicolas_upshifts" /id="U1016" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1284 /SigmaFactorBS="cttttttttgcgcctttagtacttctcgatttcgtCCAGACA CTCattatagggcaaaTGAATAGAGATATTGAGCATaccaaaatttcaagcaactaac g" /listShort="S453, yjnA" /GFF_Attribute="listLong" promotor_-35 complement(1313760..1313769) /Source="Nicolas_upshift_promotors" /id="U1016" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1284 /SigmaFactorBS="cttttttttgcgcctttagtacttctcgatttcgtCCAGACA CTCattatagggcaaaTGAATAGAGATATTGAGCATaccaaaatttcaagcaactaac g" /listShort="S453, yjnA" /GFF_Attribute="listLong" /label="promotor_-35" downshifts complement(1313837) /Source="Nicolas_upshifts" /id="D687" /incds=0 /nref=192 /ntot=236 /MaxReadThrough="2.6067" /MaxDrop="6.40442" /score="13.4353262" /energy="-7.4" /TU="NA" /idTUdmin="U1017" /TUdmin=0 /isTUend="TRUE" CDS complement(1313840..1314304) /gene="yjoA" /locus_tag="BSU_12410" /old_locus_tag="BSU12410" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 20497499; Product type f: factor" /codon_start=1 /transl_table=11 /product="putative DNA-binding protein" /protein_id="NP_389123.1" /db_xref="EnsemblGenomes-Gn:BSU12410" /db_xref="EnsemblGenomes-Tr:CAB13098" /db_xref="GOA:O34334" /db_xref="InterPro:IPR007837" /db_xref="InterPro:IPR034660" /db_xref="PDB:3DKA" /db_xref="SubtiList:BG13215" /db_xref="UniProtKB/Swiss-Prot:O34334" /translation="MCQSNQIVSHFLSHRNVTNELAEKISKDHYSYKPAETSMSAEEL VKHILTSFHLFANVIKEGNASPFQNKQEETETDLNVLAKTYTEKTVAILEQLTEEQLD REIDLTSAFGRKVTGRALLQLAMEHEIHHKGNLFVYVREMGHTELPFYQQRM*" gene complement(1313840..1314304) /gene="yjoA" /locus_tag="BSU_12410" /old_locus_tag="BSU12410" promotor_-10 complement(1314336..1314355) /Source="Nicolas_upshift_promotors" /id="U1017" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.926073926073926" /psig="0.985014985014985" /xcortree=1796 /SigmaFactorBS="ttgacatagcattttgtttcatcccacagcatatTACTTGTG aattcataaccgtTGATATAGGATTTCATTGCAccatttatttttacatatggaggag a" /listShort="yjoA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1314350) /Source="Nicolas_upshifts" /id="U1017" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.926073926073926" /psig="0.985014985014985" /xcortree=1796 /SigmaFactorBS="ttgacatagcattttgtttcatcccacagcatatTACTTGTG aattcataaccgtTGATATAGGATTTCATTGCAccatttatttttacatatggaggag a" /listShort="yjoA" /GFF_Attribute="listLong" promotor_-35 complement(1314369..1314376) /Source="Nicolas_upshift_promotors" /id="U1017" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.926073926073926" /psig="0.985014985014985" /xcortree=1796 /SigmaFactorBS="ttgacatagcattttgtttcatcccacagcatatTACTTGTG aattcataaccgtTGATATAGGATTTCATTGCAccatttatttttacatatggaggag a" /listShort="yjoA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1314390..1314399 /Source="Nicolas_upshift_promotors" /id="U1018" /multdbtbs="SigW" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1674 /SigmaFactorBS="tcaacggttatgaattcacaagtaatatgctgtgggaTGAAA CAAAAtgctatgtcaaTCGTATATATAACGTTcacaaaacatgaaatggagtataaac a" /listShort="yjoB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1314411..1314426 /Source="Nicolas_upshift_promotors" /id="U1018" /multdbtbs="SigW" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1674 /SigmaFactorBS="tcaacggttatgaattcacaagtaatatgctgtgggaTGAAA CAAAAtgctatgtcaaTCGTATATATAACGTTcacaaaacatgaaatggagtataaac a" /listShort="yjoB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1314413 /Source="Nicolas_upshifts" /id="U1018" /multdbtbs="SigW" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1674 /SigmaFactorBS="tcaacggttatgaattcacaagtaatatgctgtgggaTGAAA CAAAAtgctatgtcaaTCGTATATATAACGTTcacaaaacatgaaatggagtataaac a" /listShort="yjoB" /GFF_Attribute="listLong" CDS 1314453..1315724 /gene="yjoB" /locus_tag="BSU_12420" /old_locus_tag="BSU12420" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:14757246" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 14757246; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="informational ATPase possibly involved in protein degradation" /protein_id="NP_389124.1" /db_xref="EnsemblGenomes-Gn:BSU12420" /db_xref="EnsemblGenomes-Tr:CAB13099" /db_xref="GOA:O34703" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR003959" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG13216" /db_xref="UniProtKB/Swiss-Prot:O34703" /translation="MTNIPFIYQYEEKENERAAAGYGTFGYLITRIEETLYDQYGVFY ELYASDDPNTEYWELLVEDVRSGSLEPEHVAYIFEKLEKKTFAYDEDEKEPDYTVHKS IRNSVYAYPEKGVAFARIPYFQDGSIMSFDCLFAVNDEKMRAFLEGVRPRLWEKSKRK VTVFTDGDGGTSREQEAIVREVQRSQVIMNPLLKKEIYRSIDQFFHSDKSFYQTYDIP YKRGILLYGPPGNGKTTLVKSIAGSIDAPVAYWQITEFTSSETIEEVFQAARRLAPAV LVIEDIDSMPEDVRSFFLNTLDGATSKEGLFLIGTTNYPEEIDPGLMNRAGRFDRAYE IGLPDEELRLEYMKMRGFGIFLSEGEIKNAAKLTEGFSFAQLGELYVSSALQWHQEGN HHIETMVKDMTGEQRKSQRGSWMERNKVGFH*" gene 1314453..1315724 /gene="yjoB" /locus_tag="BSU_12420" /old_locus_tag="BSU12420" downshifts 1315697 /Source="Nicolas_upshifts" /id="D688" /incds=0 /nref=31 /ntot=186 /MaxReadThrough="2.4959" /MaxDrop="3.90459" /score="20.8794231" /energy="-13" /TU="NA" /idTUdmin="U1018" /TUdmin=0 /isTUend="TRUE" promotor_-35 1315803..1315810 /Source="Nicolas_upshift_promotors" /id="U1019" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.943056943056943" /psig="0.998001998001998" /xcortree=469 /SigmaFactorBS="ttgcggttagccgaaattcgacaattgcggttattttgcgTT CTTCTTtttcttgtaaaTATGATAAAATATGACATATctcgggtaattcaaaaggggg g" /listShort="rapA, phrA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1315822..1315841 /Source="Nicolas_upshift_promotors" /id="U1019" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.943056943056943" /psig="0.998001998001998" /xcortree=469 /SigmaFactorBS="ttgcggttagccgaaattcgacaattgcggttattttgcgTT CTTCTTtttcttgtaaaTATGATAAAATATGACATATctcgggtaattcaaaaggggg g" /listShort="rapA, phrA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1315823 /Source="Nicolas_upshifts" /id="U1019" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.943056943056943" /psig="0.998001998001998" /xcortree=469 /SigmaFactorBS="ttgcggttagccgaaattcgacaattgcggttattttgcgTT CTTCTTtttcttgtaaaTATGATAAAATATGACATATctcgggtaattcaaaaggggg g" /listShort="rapA, phrA" /GFF_Attribute="listLong" upshifts complement(1315846) /Source="Nicolas_upshifts" /id="U1020" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.996003996003996" /psig="0.001998001998002" /xcortree=720 /SigmaFactorBS="ccgacataagaggacggaatcgtctgcttcaTCCTCaattaa tcCCCCCTTTTGAATTAcccgagatatgtcatattttatcatatttacaagaaaaaga a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 complement(1315848..1315862) /Source="Nicolas_upshift_promotors" /id="U1020" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.996003996003996" /psig="0.001998001998002" /xcortree=720 /SigmaFactorBS="ccgacataagaggacggaatcgtctgcttcaTCCTCaattaa tcCCCCCTTTTGAATTAcccgagatatgtcatattttatcatatttacaagaaaaaga a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" CDS 1315869..1317005 /gene="rapA" /locus_tag="BSU_12430" /old_locus_tag="BSU12430" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:11587784, 15805512, 15916600, 22267516, 22720735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11587784, 15805512, 15916600, 22267516, 22720735; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="response regulator aspartate phosphatase" /protein_id="NP_389125.1" /db_xref="EnsemblGenomes-Gn:BSU12430" /db_xref="EnsemblGenomes-Tr:CAB13100" /db_xref="GOA:Q00828" /db_xref="InterPro:IPR011990" /db_xref="InterPro:IPR013026" /db_xref="InterPro:IPR019734" /db_xref="SubtiList:BG10652" /db_xref="UniProtKB/Swiss-Prot:Q00828" /translation="MRMKQTIPSSYVGLKINEWYTHIRQFHVAEAERVKLEVEREIED MEEDQDLLLYYSLMEFRHRVMLDYIKPFGEDTSQLEFSELLEDIEGNQYKLTGLLEYY FNFFRGMYEFKQKMFVSAMMYYKRAEKNLALVSDDIEKAEFAFKMAEIFYNLKQTYVS MSYAVQALETYQMYETYTVRRIQCEFVIAGNYDDMQYPERALPHLELALDLAKKEGNP RLISSALYNLGNCYEKMGELQKAAEYFGKSVSICKSEKFDNLPHSIYSLTQVLYKQKN DAEAQKKYREGLEIARQYSDELFVELFQFLHALYGKNIDTESVSHTFQFLEEHMLYPY IEELAHDAAQFYIENGQPEKALSFYEKMVHAQKQIQRGDCLYEI*" gene 1315869..1317005 /gene="rapA" /locus_tag="BSU_12430" /old_locus_tag="BSU12430" promotor_-35 complement(1315871..1315875) /Source="Nicolas_upshift_promotors" /id="U1020" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.996003996003996" /psig="0.001998001998002" /xcortree=720 /SigmaFactorBS="ccgacataagaggacggaatcgtctgcttcaTCCTCaattaa tcCCCCCTTTTGAATTAcccgagatatgtcatattttatcatatttacaagaaaaaga a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" CDS 1316995..1317129 /gene="phrA" /locus_tag="BSU_12440" /old_locus_tag="BSU12440" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:1378051, 10629174, 11587784, 16816200, 17666034, 19380751, 20238180, 22267516" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1378051, 10629174, 11587784, 16816200, 17666034, 19380751, 20238180, 22267516; Product type f: factor" /codon_start=1 /transl_table=11 /product="secreted inhibitor of the activity of phosphatase RapA (quorum sensing)" /protein_id="NP_389126.1" /db_xref="EnsemblGenomes-Gn:BSU12440" /db_xref="EnsemblGenomes-Tr:CAB13101" /db_xref="SubtiList:BG10653" /db_xref="UniProtKB/Swiss-Prot:Q00829" /translation="MKSKWMSGLLLVAVGFSFTQVMVHAGETANTEGKTFHIAARNQT *" gene 1316995..1317129 /gene="phrA" /locus_tag="BSU_12440" /old_locus_tag="BSU12440" downshifts 1317127 /Source="Nicolas_upshifts" /id="D689" /incds=0 /nref=257 /ntot=265 /MaxReadThrough="2.54197" /MaxDrop="9.28084" /score="10.6385823" /energy="-17" /TU="U1019" /idTUdmin="U1019" /TUdmin="-22" /isTUend="TRUE" CDS complement(1317157..1317414) /gene="yjpA" /locus_tag="BSU_12450" /old_locus_tag="BSU12450" /function="18.1: Enzymes of unknown specificity" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15779043; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative enzyme" /protein_id="NP_389127.2" /db_xref="EnsemblGenomes-Gn:BSU12450" /db_xref="EnsemblGenomes-Tr:CAB13102" /db_xref="InterPro:IPR005545" /db_xref="InterPro:IPR011008" /db_xref="SubtiList:BG13217" /db_xref="UniProtKB/Swiss-Prot:O34446" /translation="MYTYLMLTMRTEKFNQEHVAGHYEFLDRLQAEKRLKMFGPFSDA TGGAYVIEADSLEEAAEIGHADPLVASGSSELTIKEWKLKK*" gene complement(1317157..1317414) /gene="yjpA" /locus_tag="BSU_12450" /old_locus_tag="BSU12450" downshifts complement(1317178) /Source="Nicolas_upshifts" /id="D690" /incds=0 /nref=201 /ntot=255 /MaxReadThrough="0.7939" /MaxDrop="6.43836" /score="0.0520712077" /energy="-3.2" /TU="NA" /idTUdmin="U1021" /TUdmin=0 /isTUend="TRUE" misc_feature complement(1317428..1317447) /Source="Nicolas_upshift_promotors" /id="U1021" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.97902097902098" /psig=1 /xcortree=3193 /SigmaFactorBS="ggtggcattcgtaggacgaaaagctcatatcatctatcaccg taatatggataaaTGTGTTAAACTGAAGTTCACggagggtctgaatatgtatacatat t" /listShort="yjpA" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(1317442) /Source="Nicolas_upshifts" /id="U1021" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.97902097902098" /psig=1 /xcortree=3193 /SigmaFactorBS="ggtggcattcgtaggacgaaaagctcatatcatctatcaccg taatatggataaaTGTGTTAAACTGAAGTTCACggagggtctgaatatgtatacatat t" /listShort="yjpA" /GFF_Attribute="listLong" misc_feature 1317486..1317504 /Source="Nicolas_upshift_promotors" /id="U1022" /multdbtbs="-" /comp="M12" /sig="Sig-" /pcomp=1 /psig=0 /xcortree=1524 /SigmaFactorBS="agtttaacacatttatccatattacggtgatagatgatatga gcttttcGTCCTACGAATGCCACCTAtttatgaaaaaagaaaaggagagatgataggt g" /listShort="xlyB" /listLong="yjqB, yjqC" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 1317497 /Source="Nicolas_upshifts" /id="U1022" /multdbtbs="-" /comp="M12" /sig="Sig-" /pcomp=1 /psig=0 /xcortree=1524 /SigmaFactorBS="agtttaacacatttatccatattacggtgatagatgatatga gcttttcGTCCTACGAATGCCACCTAtttatgaaaaaagaaaaggagagatgataggt g" /listShort="xlyB" /listLong="yjqB, yjqC" CDS 1317535..1318488 /gene="xlyB" /locus_tag="BSU_12460" /old_locus_tag="BSU12460" /EC_number="3.5.1.28" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:8760915, 9555893" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8760915, 9555893; Product type h: extrachromosomal origin" /codon_start=1 /transl_table=11 /product="phage PBSX; N-acetylmuramoyl-L-alanine amidase" /protein_id="NP_389128.1" /db_xref="EnsemblGenomes-Gn:BSU12460" /db_xref="EnsemblGenomes-Tr:CAB13103" /db_xref="GOA:O34391" /db_xref="InterPro:IPR002477" /db_xref="InterPro:IPR002502" /db_xref="InterPro:IPR018392" /db_xref="InterPro:IPR036365" /db_xref="InterPro:IPR036366" /db_xref="InterPro:IPR036505" /db_xref="InterPro:IPR036779" /db_xref="SubtiList:BG12699" /db_xref="UniProtKB/Swiss-Prot:O34391" /translation="MSIPVKKNLVSEAKYALKCPNAMSAEYITIHNTANDASAANEIS YMIGNTSSTSFHFAVDDQEVIQGLPLNRNAWHTGDGTNGPGNRKSIGVEICYSKSGGP KYEAAEALAISFVAQLLKERGWGIDRVRKHQDWSGKYCPHRILSEGRWDQVKAAIEKE LNGGVSAKKAAVSSSASEYHVKKGDTLSGIAASHGASVKTLQSINHITDPNHIKIGQV IKLPQTASASKSHAASSYPLPSGVIKVTSPLTQGTKVKQVQTALAALYFYPDKGAKNH GVDGVYGPKTANAVKRFQSVSGLTADGIYGPKTKAKMEEKL*" gene 1317535..1318488 /gene="xlyB" /locus_tag="BSU_12460" /old_locus_tag="BSU12460" promotor_no_box 1318383..1318483 /Source="Nicolas_upshift_promotors" /id="U1023" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.543456543456543" /psig="0.013986013986014" /xcortree=1484 /SigmaFactorBS="cccgaaaacagctaatgcagtgaaacgttttcagtctgtcag cggtttaacggctgatgggatttacggtccgaaaacgaaagcgaagatggaggaaaag c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_no_box" upshifts 1318443 /Source="Nicolas_upshifts" /id="U1023" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.543456543456543" /psig="0.013986013986014" /xcortree=1484 /SigmaFactorBS="cccgaaaacagctaatgcagtgaaacgttttcagtctgtcag cggtttaacggctgatgggatttacggtccgaaaacgaaagcgaagatggaggaaaag c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" downshifts 1318492 /Source="Nicolas_upshifts" /id="D691" /incds=0 /nref=8 /ntot=146 /MaxReadThrough="3.91295" /MaxDrop="4.29119" /score="10.6385823" /energy="-17" /TU="U1022" /idTUdmin="U1023" /TUdmin="-17" /isTUend="TRUE" downshifts complement(1318497) /Source="Nicolas_upshifts" /id="D692" /incds=0 /nref=2 /ntot=163 /MaxReadThrough="2.88318" /MaxDrop="3.60856" /score="14.6077768" /energy="-16" /TU="U1024" /idTUdmin="U1024" /TUdmin="-22" /isTUend="TRUE" CDS complement(1318528..1318905) /gene="yjqA" /locus_tag="BSU_12470" /old_locus_tag="BSU12470" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; Product type h: extrachromosomal origin" /codon_start=1 /transl_table=11 /product="phage PBSX; conserved hypothetical protein" /protein_id="NP_389129.1" /db_xref="EnsemblGenomes-Gn:BSU12470" /db_xref="EnsemblGenomes-Tr:CAB13104" /db_xref="InterPro:IPR011993" /db_xref="InterPro:IPR012544" /db_xref="InterPro:IPR037063" /db_xref="SubtiList:BG13218" /db_xref="UniProtKB/Swiss-Prot:O34593" /translation="MGFIDGLLGNASTLSTAAVQEELAHILLEGEKVEAAFKLVRDLI VFTDKRLILVDKQGITGKKTEFQSIPYKSISRFSVETAGRFDLDSELKIWISGAELPA VSKQFKKDESIYDIQKVLAAVCM*" gene complement(1318528..1318905) /gene="yjqA" /locus_tag="BSU_12470" /old_locus_tag="BSU12470" promotor_-10 complement(1318925..1318944) /Source="Nicolas_upshift_promotors" /id="U1024" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.304695304695305" /psig="0.993006993006993" /xcortree=2203 /SigmaFactorBS="cccctttaccagtcagcaccagtttactctactcatCTATGA AtgaaaacctttttTATAGTATGATTTGATAGAAtacgcagaggaggtatatgatggg g" /listShort="yjqA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1318940) /Source="Nicolas_upshifts" /id="U1024" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.304695304695305" /psig="0.993006993006993" /xcortree=2203 /SigmaFactorBS="cccctttaccagtcagcaccagtttactctactcatCTATGA AtgaaaacctttttTATAGTATGATTTGATAGAAtacgcagaggaggtatatgatggg g" /listShort="yjqA" /GFF_Attribute="listLong" promotor_-35 1318950..1318954 /Source="Nicolas_upshift_promotors" /id="U1025" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.522477522477522" /psig="0.993006993006993" /xcortree=2682 /SigmaFactorBS="tcctctgcgtattctatcaaatcatactataaaaaaGGTTTt cattcatagatgagTAGAGTAAACTGGTGCTGACtggtaaaggggggcgttcaagatg g" /listShort="yjqB, yjqC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 complement(1318958..1318964) /Source="Nicolas_upshift_promotors" /id="U1024" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.304695304695305" /psig="0.993006993006993" /xcortree=2203 /SigmaFactorBS="cccctttaccagtcagcaccagtttactctactcatCTATGA AtgaaaacctttttTATAGTATGATTTGATAGAAtacgcagaggaggtatatgatggg g" /listShort="yjqA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1318970..1318989 /Source="Nicolas_upshift_promotors" /id="U1025" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.522477522477522" /psig="0.993006993006993" /xcortree=2682 /SigmaFactorBS="tcctctgcgtattctatcaaatcatactataaaaaaGGTTTt cattcatagatgagTAGAGTAAACTGGTGCTGACtggtaaaggggggcgttcaagatg g" /listShort="yjqB, yjqC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1318974 /Source="Nicolas_upshifts" /id="U1025" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.522477522477522" /psig="0.993006993006993" /xcortree=2682 /SigmaFactorBS="tcctctgcgtattctatcaaatcatactataaaaaaGGTTTt cattcatagatgagTAGAGTAAACTGGTGCTGACtggtaaaggggggcgttcaagatg g" /listShort="yjqB, yjqC" /GFF_Attribute="listLong" CDS 1319011..1319613 /gene="pghB" /locus_tag="BSU_12480" /old_locus_tag="BSU12480" /EC_number="3.4.19.-" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2b: Function from indirect experimental evidences (e.g. phenotypes); PubMedId: 8760915, 15466572, 26158264; Product type h: extrachromosomal origin" /codon_start=1 /transl_table=11 /product="phage PBSX; gamma-polyglutamate hydrolase" /protein_id="NP_389130.1" /db_xref="EnsemblGenomes-Gn:BSU12480" /db_xref="EnsemblGenomes-Tr:CAB13105" /db_xref="InterPro:IPR008585" /db_xref="SubtiList:BG13219" /db_xref="UniProtKB/Swiss-Prot:O34785" /translation="MEDMYDSFAALSASESEYRIIYEEKNGSELIVLGPHGGRIEPGV SELVRAFSDRCSIYLFEGLKQRNNRSLHLTSIRFDEPLALEKVNDHHYALAFHGYYDP KIPHTLVGGADRKKAKLICERLNEAGFSAELTNEKDRLAGVHPNNIVNRTKREMGLQL EVSTAQRNALFRNFGCRDKSYIQNDLFDRYVEAVKLGFYT*" gene 1319011..1319613 /gene="pghB" /locus_tag="BSU_12480" /old_locus_tag="BSU12480" promotor_-35 1319625..1319634 /Source="Nicolas_upshift_promotors" /id="U1026" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=1363 /SigmaFactorBS="cttggcttttatacataaaactagacgggACCTGCACGGttg gcctattccTTCATACGCTGGGGTTGTGCgaaagtgtggggaggaatgattcatgttt t" /listShort="yjqC" /GFF_Attribute="listLong" /label="promotor_-35" S_feature complement(1319640..1320569) /Source="Nicolas_S_feature" /locus_tag="new_1319640_1320569_c" /HighExp="M40t90, M40t45, H2O2, Cold, LBGstat, Etha, Sw, T0.30H, Heat, T1.0H" /AntisenseName="yjqC" /AntisenseCor="-0.110813865274572" /AntisenseRegPval="-1.2" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S454" promotor_-10 1319647..1319666 /Source="Nicolas_upshift_promotors" /id="U1026" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=1363 /SigmaFactorBS="cttggcttttatacataaaactagacgggACCTGCACGGttg gcctattccTTCATACGCTGGGGTTGTGCgaaagtgtggggaggaatgattcatgttt t" /listShort="yjqC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1319656 /Source="Nicolas_upshifts" /id="U1026" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=1363 /SigmaFactorBS="cttggcttttatacataaaactagacgggACCTGCACGGttg gcctattccTTCATACGCTGGGGTTGTGCgaaagtgtggggaggaatgattcatgttt t" /listShort="yjqC" /GFF_Attribute="listLong" CDS 1319690..1320526 /gene="xpdC" /locus_tag="BSU_12490" /old_locus_tag="BSU12490" /EC_number="1.11.1.-" /function="16.5: Explore" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1c: Function from experimental evidences in the studied genus; PubMedId: 8760915, 15466572, 22752169, 27362423; Product type h: extrachromosomal origin" /codon_start=1 /transl_table=11 /product="phage PBSX; manganese-containing peroxidase" /protein_id="NP_389131.2" /db_xref="EnsemblGenomes-Gn:BSU12490" /db_xref="EnsemblGenomes-Tr:CAB13106" /db_xref="GOA:O34423" /db_xref="InterPro:IPR007760" /db_xref="InterPro:IPR009078" /db_xref="InterPro:IPR012347" /db_xref="InterPro:IPR027407" /db_xref="SubtiList:BG13220" /db_xref="UniProtKB/Swiss-Prot:O34423" /translation="MFYHIKELQYQAKPAHPDPVYAKKLQEVLGGQFGEISVMMQYLF QGFNCRADAKYKDLLYDVGTEEIGHVEMLATMISRLLDNAPADVQEDAYKSNPAIAAV MSGMNPQHAIVSGLGAMASDSEGYPWNAKYIISSGNLLADFRANLNAEAQGRLQVTRL YAMTDDPGVRDMLSFLIARDTYHQNMWYAAIKELEERERDIVVPTTFPRELEKQEVSY DLFNFSRGDESSQGRWAHGEAFDGRGEFRYIPAPIAFASAPHLKPAPMWLHNTVPPMS KC*" gene 1319690..1320526 /gene="xpdC" /locus_tag="BSU_12490" /old_locus_tag="BSU12490" downshifts 1320514 /Source="Nicolas_upshifts" /id="D693" /incds=0 /nref=4 /ntot=53 /MaxReadThrough="2.02835" /MaxDrop="3.83938" /score="0.0878183333" /energy="-20.1" /TU="NA" /idTUdmin="U1026" /TUdmin=0 /isTUend="TRUE" CDS complement(1320570..1321166) /gene="xkdA" /locus_tag="BSU_12500" /old_locus_tag="BSU12500" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:8760915, 16267290, 22933559" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8760915, 16267290, 22933559; Product type h: extrachromosomal origin" /codon_start=1 /transl_table=11 /product="phage PBSX; putative peptidase" /protein_id="NP_389132.3" /db_xref="EnsemblGenomes-Gn:BSU12500" /db_xref="EnsemblGenomes-Tr:CAB13107" /db_xref="InterPro:IPR010359" /db_xref="SubtiList:BG10993" /db_xref="UniProtKB/Swiss-Prot:P39780" /translation="MGDYLSHLEEYVKNLYGRLGITSPHHIDMLKIAKDLDIWVHFED MGSMMVKYDGMYSIVLNQKKSREEQWEDFGHELCHVLKHAGNHFQMNKLFRELQEFQA NQFMYHFCVPTFMLLQMELPQWRSQALATIAAVFRVTKEFADKRLDMFERRKAGIQFQ KRLAYLLSHKRPNAYEEGDQQHLQVAEEKALYHIGKNI*" gene complement(1320570..1321166) /gene="xkdA" /locus_tag="BSU_12500" /old_locus_tag="BSU12500" S_feature complement(1321205..1321328) /Source="Nicolas_S_feature" /locus_tag="new_1321205_1321328_c" /HighExp="HiTm, MG 10, MG 5, MG-0.1, MG 25, GM 120, MG 45, GM 15, Lbtran, LBGstat" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S455" downshifts complement(1321248) /Source="Nicolas_upshifts" /id="D694" /incds=0 /nref=10 /ntot=151 /MaxReadThrough="4.55391" /MaxDrop="3.62157" /score="-8.64059763" /energy="-7.9" /TU="U1027" /idTUdmin="U1027" /TUdmin="-1582" /isTUend="FALSE" CDS complement(1321329..1321670) /gene="xre" /locus_tag="BSU_12510" /old_locus_tag="BSU12510" /function="16.3: Control" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:8083175, 20889742" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8083175, 20889742; Product type h: extrachromosomal origin" /codon_start=1 /transl_table=11 /product="phage PBSX transcriptional regulator" /protein_id="NP_389133.1" /db_xref="EnsemblGenomes-Gn:BSU12510" /db_xref="EnsemblGenomes-Tr:CAB13108" /db_xref="GOA:P23789" /db_xref="InterPro:IPR001387" /db_xref="InterPro:IPR010982" /db_xref="SubtiList:BG10994" /db_xref="UniProtKB/Swiss-Prot:P23789" /translation="MIGGRLKSLRGKRTQEEIASHIGVSRARYSHYENGRSEPDYDTL QKLADYFQVTTDYLLTGKDKKSDDDMFSDPDLQLAYRDMQDFSPESKQQAIEFINYLK EKEKNRKPKNK*" gene complement(1321329..1321670) /gene="xre" /locus_tag="BSU_12510" /old_locus_tag="BSU12510" promotor_-10 complement(1321702..1321721) /Source="Nicolas_upshift_promotors" /id="U1027" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.448551448551449" /psig="0.999000999001" /xcortree=3029 /SigmaFactorBS="tcaagttatttttgatactttttttatcataaCTTTATTttg atacattttGTATCTATAATCATAAGTAAcgtagggagtttaaaaaagagaggtcata g" /listShort="xre, S455, xkdA, S454" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1321712) /Source="Nicolas_upshifts" /id="U1027" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.448551448551449" /psig="0.999000999001" /xcortree=3029 /SigmaFactorBS="tcaagttatttttgatactttttttatcataaCTTTATTttg atacattttGTATCTATAATCATAAGTAAcgtagggagtttaaaaaagagaggtcata g" /listShort="xre, S455, xkdA, S454" /GFF_Attribute="listLong" promotor_-35 complement(1321734..1321740) /Source="Nicolas_upshift_promotors" /id="U1027" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.448551448551449" /psig="0.999000999001" /xcortree=3029 /SigmaFactorBS="tcaagttatttttgatactttttttatcataaCTTTATTttg atacattttGTATCTATAATCATAAGTAAcgtagggagtttaaaaaagagaggtcata g" /listShort="xre, S455, xkdA, S454" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1321768..1321771 /Source="Nicolas_upshift_promotors" /id="U1028" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.811188811188811" /psig=1 /xcortree=1519 /SigmaFactorBS="tcaaaataaagttatgataaaaaaagtatcaaaaataaCTTG atgatacagaatgtATCGTTTATACTTGGTAACAtccgatacaaaatgtatcaaaaaa g" /listShort="yjzJ" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1321786..1321805 /Source="Nicolas_upshift_promotors" /id="U1028" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.811188811188811" /psig=1 /xcortree=1519 /SigmaFactorBS="tcaaaataaagttatgataaaaaaagtatcaaaaataaCTTG atgatacagaatgtATCGTTTATACTTGGTAACAtccgatacaaaatgtatcaaaaaa g" /listShort="yjzJ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1321790 /Source="Nicolas_upshifts" /id="U1028" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.811188811188811" /psig=1 /xcortree=1519 /SigmaFactorBS="tcaaaataaagttatgataaaaaaagtatcaaaaataaCTTG atgatacagaatgtATCGTTTATACTTGGTAACAtccgatacaaaatgtatcaaaaaa g" /listShort="yjzJ" /GFF_Attribute="listLong" CDS 1321848..1322027 /gene="yjzJ" /locus_tag="BSU_12519" /old_locus_tag="BSU12519" /function="18: Unknown function" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; Product type h: extrachromosomal origin" /codon_start=1 /transl_table=11 /product="phage PBSX; conserved hypothetical protein" /protein_id="YP_003097711.1" /db_xref="EnsemblGenomes-Gn:BSU12519" /db_xref="EnsemblGenomes-Tr:CAX52601" /db_xref="UniProtKB/Swiss-Prot:C0H3Z4" /translation="MYPIQIVFSENPIDQRHLGQSGGTISFTACGLPVFHFETQEQFQ AYMMLKGEAAYNEKR*" gene 1321848..1322027 /gene="yjzJ" /locus_tag="BSU_12519" /old_locus_tag="BSU12519" CDS 1322014..1322850 /gene="xkdB" /locus_tag="BSU_12520" /old_locus_tag="BSU12520" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="phage PBSX; conserved hypothetical protein" /protein_id="NP_389134.2" /db_xref="EnsemblGenomes-Gn:BSU12520" /db_xref="EnsemblGenomes-Tr:CAB13109" /db_xref="GOA:P39781" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG10995" /db_xref="UniProtKB/Swiss-Prot:P39781" /translation="MKNDKSYPFPTYSGLLNSEHYDKIGPALWLFLWFISSTTKEIEK DGVSWGIVLGHKPLKAREMAAVFGVSEKTVRRWLELLENHDYIKAVRAPYGLMISVKH SKKFSFRSDNTVHGSLKERPFSPQTPDTNDRTDIDKTNKYTAADDAVDHIAKRFTQLR SAQEGRTVYPSSRDYQAIARIVAIGVPVTQTIKWLEECFQAFENRRTAASETIKAFRY CSKFIEDRFFAQQAKKNAAIQHERMKKHDKTNNRTDFGRAEKRETSITGGQTGRIRRK QV*" gene 1322014..1322850 /gene="xkdB" /locus_tag="BSU_12520" /old_locus_tag="BSU12520" CDS 1322750..1323550 /gene="xkdC" /locus_tag="BSU_12530" /old_locus_tag="BSU12530" /function="18: Unknown function" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type h : extrachromosomal origin" /codon_start=1 /transl_table=11 /product="phage PBSX; putative DNA binding protein" /protein_id="NP_389135.2" /db_xref="EnsemblGenomes-Gn:BSU12530" /db_xref="EnsemblGenomes-Tr:CAB13110" /db_xref="GOA:P39782" /db_xref="InterPro:IPR002611" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG10996" /db_xref="UniProtKB/Swiss-Prot:P39782" /translation="MTKRTIEQILDELRRGRRPLLADKPAESDASRYDCLRCKDQGGY LVRQNGLEVWTMCSCMAERKVKRLLGASEITHAFRQLGFKEFRTEGKPQAIKDAFECT KEYVADYEQIKDCRKNSIALLGQPGSGKTHLLTAAANELMRTCYVPVIYFPFVEGFTD LKNDFALLEAKLNRMKQADVLFIDDLFKPVNGKPRATDWQLEQMYSVLNYRYLNHKPI LLSSELTIEGLVRVDEALGTRIYEMCSDYLVIIKGAAYELNHRLEGVR*" gene 1322750..1323550 /gene="xkdC" /locus_tag="BSU_12530" /old_locus_tag="BSU12530" CDS 1323550..1323717 /gene="ykzK" /locus_tag="BSU_12539" /old_locus_tag="BSU12539" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; Product type h: extrachromosomal origin" /codon_start=1 /transl_table=11 /product="phage PBSX; conserved hypothetical protein" /protein_id="YP_003097712.1" /db_xref="EnsemblGenomes-Gn:BSU12539" /db_xref="EnsemblGenomes-Tr:CAX52602" /db_xref="UniProtKB/Swiss-Prot:C0H3Z5" /translation="MCKLCQTKKVIVEHTGIGVVFHPCPNCRSGTDLTPVIQKLEQML TAGKARLNIYD*" gene 1323550..1323717 /gene="ykzK" /locus_tag="BSU_12539" /old_locus_tag="BSU12539" CDS 1323802..1324152 /gene="xkdD" /locus_tag="BSU_12540" /old_locus_tag="BSU12540" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; Product type h: extrachromosomal origin" /codon_start=1 /transl_table=11 /product="phage PBSX; conserved hypothetical protein" /protein_id="NP_389136.1" /db_xref="EnsemblGenomes-Gn:BSU12540" /db_xref="EnsemblGenomes-Tr:CAB13111" /db_xref="SubtiList:BG10997" /db_xref="UniProtKB/Swiss-Prot:P39783" /translation="MKVLAKTKQAEKSPAPWRAVPCGDTKPIYIYSAYSEEEKERFPY SNGRLIAAVFDLSSYSQKSNASLMAAAPELLEASKAALDFLKGNSIHSKERIIQLLEK AEASAAPKRGGNKT*" gene 1323802..1324152 /gene="xkdD" /locus_tag="BSU_12540" /old_locus_tag="BSU12540" CDS 1324149..1324355 /gene="xtrA" /locus_tag="BSU_12550" /old_locus_tag="BSU12550" /experiment="publication(s) with functional evidences, PMID:8760915" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8760915; Product type h : extrachromosomal origin" /codon_start=1 /transl_table=11 /product="phage PBSX; conserved protein of unknown function" /protein_id="NP_389137.1" /db_xref="EnsemblGenomes-Gn:BSU12550" /db_xref="EnsemblGenomes-Tr:CAB13112" /db_xref="InterPro:IPR035530" /db_xref="SubtiList:BG11559" /db_xref="UniProtKB/Swiss-Prot:P54344" /translation="MIHPKKLLHIDSVTLKSQLEDGKIRVIIVDGIKQEAWITEAPEH GKTLVETRKGDLARVEFEIGYKLN*" gene 1324149..1324355 /gene="xtrA" /locus_tag="BSU_12550" /old_locus_tag="BSU12550" CDS 1324471..1324980 /gene="xpf" /locus_tag="BSU_12560" /old_locus_tag="BSU12560" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 8083174, 25176138; Product type h: extrachromosomal origin" /codon_start=1 /transl_table=11 /product="phage PBSX; putative RNA polymerase PBSX sigma factor-like" /protein_id="NP_389138.1" /db_xref="EnsemblGenomes-Gn:BSU12560" /db_xref="EnsemblGenomes-Tr:CAB13113" /db_xref="GOA:P39784" /db_xref="InterPro:IPR013249" /db_xref="InterPro:IPR013324" /db_xref="InterPro:IPR014284" /db_xref="InterPro:IPR036388" /db_xref="SubtiList:BG10998" /db_xref="UniProtKB/Swiss-Prot:P39784" /translation="MQDLLFEYKRTLKQTRIQYKPLAEADESVLSAEELKDKKIIRNM ITDLEYVTEWLEKGRQPGIRRAIDRRDVYQRLMIKDPRIIESFSSAMMFEPDGQVSEE DRDRIREALALLTDREKEMFLLHKVECFSYERIADLLGVKKSTVQTTIKRASLKMQRQ QEEMNRSLA*" gene 1324471..1324980 /gene="xpf" /locus_tag="BSU_12560" /old_locus_tag="BSU12560" misc_feature 1324987..1325005 /Source="Nicolas_upshift_promotors" /id="U1029" /multdbtbs="-" /comp="M12" /sig="Sig-" /pcomp=1 /psig=0 /xcortree=1522 /SigmaFactorBS="agacagcaggaagaaatgaatcgatcacttgcctgaaagctt GTCATACGTTTGCCACCTAtaagtgaatagagcatgacactaagcggctggctgatca g" /listShort="S456, xtmA, xtmB, xkdE, xkdF, xkdG, ykzL, xkdH, xkdI, xkdJ, ykzM, xkdK, xkdM, S457, xkdN, xkzB, xkdO, xkdP, xkdQ, xkdR, xkdS, xkdT, xkdU, xkzA, xkdV, xkdW, xkdX, xepA, xhlA, xhlB, xlyA" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" S_feature 1325005..1325095 /Source="Nicolas_S_feature" /locus_tag="new_1325005_1325095" /HighExp="HPh, M40t90, LPh, MG 120, MG 150, MG 90, LBGexp, MG 60, dia0, Lbexp" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.467804" /TUshortSig="Sig-" /TUshortPSig=0 /TUlongSig="NA" /TUlongPSig="NA" /label="S456" upshifts 1325005 /Source="Nicolas_upshifts" /id="U1029" /multdbtbs="-" /comp="M12" /sig="Sig-" /pcomp=1 /psig=0 /xcortree=1522 /SigmaFactorBS="agacagcaggaagaaatgaatcgatcacttgcctgaaagctt GTCATACGTTTGCCACCTAtaagtgaatagagcatgacactaagcggctggctgatca g" /listShort="S456, xtmA, xtmB, xkdE, xkdF, xkdG, ykzL, xkdH, xkdI, xkdJ, ykzM, xkdK, xkdM, S457, xkdN, xkzB, xkdO, xkdP, xkdQ, xkdR, xkdS, xkdT, xkdU, xkzA, xkdV, xkdW, xkdX, xepA, xhlA, xhlB, xlyA" /GFF_Attribute="listLong" CDS 1325096..1325893 /gene="xtmA" /locus_tag="BSU_12570" /old_locus_tag="BSU12570" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 8083174; Product type h : extrachromosomal origin" /codon_start=1 /transl_table=11 /product="phage PBSX; prophage terminase (small subunit)" /protein_id="NP_389139.1" /db_xref="EnsemblGenomes-Gn:BSU12570" /db_xref="EnsemblGenomes-Tr:CAB13114" /db_xref="GOA:P39785" /db_xref="InterPro:IPR005335" /db_xref="InterPro:IPR018925" /db_xref="SubtiList:BG10999" /db_xref="UniProtKB/Swiss-Prot:P39785" /translation="MKTQQREQALAIYQQHQGKITNRAIADTIGVSAKTIGIWKKQDK WKEALFSASKNEQKQRPINNDELNERQRLFCLYYVKSFNATQSAIKAGYSPDSAHVTG SRLLKNEKVAAEIRRIKKEMVNEMFIEAMDVLQVYIKIAFADITDYVTFGKKEVQAVG KSGPLFDEDDNPIMKEISFVDVKDSGLVDGTIVTEAKLGKEGIAIKLADKMKALEKLS LYFDLFPDQFKQKIENEKLKLAKQKAEKTDDSQEPIEIMIKRKERKS*" gene 1325096..1325893 /gene="xtmA" /locus_tag="BSU_12570" /old_locus_tag="BSU12570" CDS 1325890..1327191 /gene="xtmB" /locus_tag="BSU_12580" /old_locus_tag="BSU12580" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2b: Function from indirect experimental evidences (e.g. phenotypes); PubMedId: 17945256, 19347993; Product type h: extrachromosomal origin" /codon_start=1 /transl_table=11 /product="phage PBSX; prophage terminase (large subunit)" /protein_id="NP_389140.1" /db_xref="EnsemblGenomes-Gn:BSU12580" /db_xref="EnsemblGenomes-Tr:CAB13115" /db_xref="GOA:P39786" /db_xref="InterPro:IPR006437" /db_xref="InterPro:IPR035412" /db_xref="InterPro:IPR035413" /db_xref="SubtiList:BG11000" /db_xref="UniProtKB/Swiss-Prot:P39786" /translation="MIVKEINPHFEDYVFNWEQTYQFLVGGYGSSKSYHTALKIVLKL LKEKRTALVIREVFDTHRDSTFALFQEVIEELGLTKAVASLSSPLQLRFHNGSRIMFK GMDNPAKLKSVHNISLIWIEECSEVKYEGFKELIGRLRHPELKLHMICTTNPVGTSNW TYRHFFRDERKKRFVLDDSELYEKRTIVKGDTYYHHSTANDNLFLPESYVKQLDGLKE YDPDLYRIARKGRFGVNGIRVLPQFEVLPHDQVKKCIAAISKPIFRTGMDFGFEESYN AVVRLAVDPEKKYLYIYWEYYQNKMTDDRTAEELREFIETQELIKADSAEPKSIQYFR QQGFRMVGARKFPGSRLQYTKKVKRFKKIFCSDRCENVIYELETLTYAKDKNGALIED EFTIDPHTLSAIWYALDDYEVADMKETAHKRMRPNRERRRS*" gene 1325890..1327191 /gene="xtmB" /locus_tag="BSU_12580" /old_locus_tag="BSU12580" CDS 1327195..1328682 /gene="xkdE" /locus_tag="BSU_12590" /old_locus_tag="BSU12590" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2b: Function from indirect experimental evidences (e.g. phenotypes); PubMedId: 23027764, 23419885; Product type h: extrachromosomal origin" /codon_start=1 /transl_table=11 /product="phage PBSX; phage capsid portal protein" /protein_id="NP_389141.2" /db_xref="EnsemblGenomes-Gn:BSU12590" /db_xref="EnsemblGenomes-Tr:CAB13116" /db_xref="InterPro:IPR006430" /db_xref="InterPro:IPR006944" /db_xref="InterPro:IPR016753" /db_xref="SubtiList:BG11540" /db_xref="UniProtKB/Swiss-Prot:P54325" /translation="MHNQTVRATVFKANAAAPQTKQIYEDDFSELYGEDIIAPPYNII ELKTIAEYSTILQQCIDAYRVNITGFGFDVEYTFDVNASDVDQAKKKRAEKDWARLEA FYKCLHFDESAEMILGYAIEDREKTGNGFMEVLRDGAGKPAGIEYLDVKYMRVCGAGE PVEVSFVYEENGKMKRIKRQKRFRKYVQMINGKKVFFKEYGDPRKMDIRTGEYVNTLA EKYQANEAIHLKIGSGVYGVPRWIGNIVNLYGARKAEELNFMYFKQGRHVPAAITVEN GMLSEASYRELQEYMNDLEGVENAHKFLLIEAEGIAKEKDLHGGEDITPVSVEIKSLA EILQNDALFLEYDEKSRNKLRSAFRLPPLYTGEAQEYNRATADTARKITEEQVFQPER KTLVNKLNTLLLPELNIHDVRLTLKGPDFRDPLEIAKVLGPFITAGAVSPNDLRDLAG RVLGKTLEEWPEDIYKRPAGQDAEKTNLAALMQELKESIEDIKTS*" gene 1327195..1328682 /gene="xkdE" /locus_tag="BSU_12590" /old_locus_tag="BSU12590" promotor_-35 1328204..1328213 /Source="Nicolas_upshift_promotors" /id="U1030" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1235 /SigmaFactorBS="gaaatcaaatctttggctgaaattcTCCAAAACGAcgccttg tttctTGAATACGATGAAAAAAGCAgaaataagctgcgttccgcgttccgtctccccc c" /listShort="xkdF, xkdG, ykzL, xkdH, xkdI, xkdJ, ykzM, xkdK, xkdM, S457, xkdN, xkzB, xkdO, xkdP, xkdQ, xkdR, xkdS, xkdT, xkdU, xkzA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1328226..1328245 /Source="Nicolas_upshift_promotors" /id="U1030" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1235 /SigmaFactorBS="gaaatcaaatctttggctgaaattcTCCAAAACGAcgccttg tttctTGAATACGATGAAAAAAGCAgaaataagctgcgttccgcgttccgtctccccc c" /listShort="xkdF, xkdG, ykzL, xkdH, xkdI, xkdJ, ykzM, xkdK, xkdM, S457, xkdN, xkzB, xkdO, xkdP, xkdQ, xkdR, xkdS, xkdT, xkdU, xkzA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1328239 /Source="Nicolas_upshifts" /id="U1030" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1235 /SigmaFactorBS="gaaatcaaatctttggctgaaattcTCCAAAACGAcgccttg tttctTGAATACGATGAAAAAAGCAgaaataagctgcgttccgcgttccgtctccccc c" /listShort="xkdF, xkdG, ykzL, xkdH, xkdI, xkdJ, ykzM, xkdK, xkdM, S457, xkdN, xkzB, xkdO, xkdP, xkdQ, xkdR, xkdS, xkdT, xkdU, xkzA" /GFF_Attribute="listLong" CDS 1328702..1329529 /gene="xkdF" /locus_tag="BSU_12600" /old_locus_tag="BSU12600" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; Product type h: extrachromosomal origin" /codon_start=1 /transl_table=11 /product="phage PBSX; conserved hypothetical protein" /protein_id="NP_389142.2" /db_xref="EnsemblGenomes-Gn:BSU12600" /db_xref="EnsemblGenomes-Tr:CAB13117" /db_xref="InterPro:IPR027924" /db_xref="SubtiList:BG11541" /db_xref="UniProtKB/Swiss-Prot:P54326" /translation="MARELRNAKISFVSYVDKAANQTEFFFTKSAEPPSFEKKVRLFT KSEQDEQKLVYGIVYEPDVPDAHGDFMTAEEIEKAAHGFLAEAREIDINHSFEGGTGV VVESYVAPDDFMIGSKRITKGSWVLVTRASDEVWEQIKAGIITGYSMAGTADVYEEEP VEKAGFFSVFKQMLADKTGKETEEMRKEDMKESFEHALYPLLKRLERIEKNTDTEEKP EQTGDDERLKKLVEDMLAPLIERIEALEKARGASKQTADDTGGNTEQVKKSIWSGLL* " gene 1328702..1329529 /gene="xkdF" /locus_tag="BSU_12600" /old_locus_tag="BSU12600" CDS 1329555..1330490 /gene="xkdG" /locus_tag="BSU_12610" /old_locus_tag="BSU12610" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 12897825; Product type h: extrachromosomal origin" /codon_start=1 /transl_table=11 /product="phage PBSX; putative phage chromosome binding protein" /protein_id="NP_389143.1" /db_xref="EnsemblGenomes-Gn:BSU12610" /db_xref="EnsemblGenomes-Tr:CAB13118" /db_xref="GOA:P54327" /db_xref="InterPro:IPR024455" /db_xref="SubtiList:BG11542" /db_xref="UniProtKB/Swiss-Prot:P54327" /translation="MRNQEIIRKAEMSLSALKSGGLMNPAQASAFIRMVQNTPTIFSE SRVIQMENDSQKFEKIGFGQRILRAAQEGKALSNDELTVPTTSTVQLNTKEVIAEINI TYDTLENNIEKDGLQQTIMQILAERAAVDIEELIVNGDTASADPYLAQLDGIRKQAVS HIVDMNGEELSRATFKKGLKAVPPKYLRIPQEFRFYTSHGLEVEWKDRVADRQTNLGD QAVQGGLSTAFGVPVKGVSNIQPYTVGEGDAQYDASDIILTHPKNIILGFSRNIRIEV DKDIRSRKFIIVLTAKLDSKFEEEDACAKLINVKE*" gene 1329555..1330490 /gene="xkdG" /locus_tag="BSU_12610" /old_locus_tag="BSU12610" CDS 1330512..1330895 /gene="ykzL" /locus_tag="BSU_12619" /old_locus_tag="BSU12619" /function="18: Unknown function" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; Product type h: extrachromosomal origin" /codon_start=1 /transl_table=11 /product="phage PBSX; conserved hypothetical protein" /protein_id="YP_003097713.1" /db_xref="EnsemblGenomes-Gn:BSU12619" /db_xref="EnsemblGenomes-Tr:CAX52603" /db_xref="InterPro:IPR013514" /db_xref="InterPro:IPR036558" /db_xref="UniProtKB/Swiss-Prot:C0H3Z6" /translation="MLIEPTDVASYSVYDRVKNRPEELLAQDIIEAEAEAALITGHRF EDSLYDPLPGKVKLALVKLAQYFALVNSDESASSSYQYEKMGDYSYTVSGEGRIQRPE VYHLLEEFIKPGYVPESSRLKVRSL*" gene 1330512..1330895 /gene="ykzL" /locus_tag="BSU_12619" /old_locus_tag="BSU12619" CDS 1330892..1331248 /gene="xkdH" /locus_tag="BSU_12620" /old_locus_tag="BSU12620" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; Product type h: extrachromosomal origin" /codon_start=1 /transl_table=11 /product="phage PBSX; conserved hypothetical protein" /protein_id="NP_389144.1" /db_xref="EnsemblGenomes-Gn:BSU12620" /db_xref="EnsemblGenomes-Tr:CAB13119" /db_xref="InterPro:IPR024556" /db_xref="PDB:3F3B" /db_xref="SubtiList:BG11543" /db_xref="UniProtKB/Swiss-Prot:P54328" /translation="MSYRQMLIHRCDIYHEAAQAPSAGRFGIPADRLQPVISYPDTPD EQDVPCYFTEKTQQLIQEEPDQTVYHSFLVHFPLSADIRVNDKIIWENHKYILKLPKR IRHHHWEVVAVRDESL*" gene 1330892..1331248 /gene="xkdH" /locus_tag="BSU_12620" /old_locus_tag="BSU12620" CDS 1331245..1331730 /gene="xkdI" /locus_tag="BSU_12630" /old_locus_tag="BSU12630" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; Product type h: extrachromosomal origin" /codon_start=1 /transl_table=11 /product="phage PBSX; conserved hypothetical protein" /protein_id="NP_389145.1" /db_xref="EnsemblGenomes-Gn:BSU12630" /db_xref="EnsemblGenomes-Tr:CAB13120" /db_xref="InterPro:IPR010064" /db_xref="SubtiList:BG11544" /db_xref="UniProtKB/Swiss-Prot:P54329" /translation="MKIAGLKQLNTALKEAASGGFSRQASRWLEECGQDFLEIVQSEL ISTQTIDTEKLLSSFEKGAEDNLWIVQSGGLSLEVGTQLDYASFLNDGHWTSKQDVRW VPGRFQGSRFIYDPAASTGMALKRKWIPGTGYWDHALLLYEQLFEKSLESKLRQWLKK L*" gene 1331245..1331730 /gene="xkdI" /locus_tag="BSU_12630" /old_locus_tag="BSU12630" CDS 1331743..1332183 /gene="xkdJ" /locus_tag="BSU_12640" /old_locus_tag="BSU12640" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; Product type h: extrachromosomal origin" /codon_start=1 /transl_table=11 /product="phage PBSX; conserved hypothetical protein" /protein_id="NP_389146.1" /db_xref="EnsemblGenomes-Gn:BSU12640" /db_xref="EnsemblGenomes-Tr:CAB13121" /db_xref="SubtiList:BG11545" /db_xref="UniProtKB/Swiss-Prot:P54330" /translation="MNSETGSIMAFLYSRWSVPIYERELPDHFQVPSLYVPPPSVFEE TDTVSTFKKTYSLNVKLFHLDSVQALDEADRLADAIREARNMIPLLSESGEKTGDMVR ISQIETRVGDRGEAAMVIRWSSRYYYHKTEQPVLQDIDMNSGVK*" gene 1331743..1332183 /gene="xkdJ" /locus_tag="BSU_12640" /old_locus_tag="BSU12640" CDS 1332187..1332405 /gene="ykzM" /locus_tag="BSU_12649" /old_locus_tag="BSU12649" /function="17.2: Prophage functions" /function="18: Unknown function" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; Product type h: extrachromosomal origin" /codon_start=1 /transl_table=11 /product="phage PBSX; conserved hypothetical protein" /protein_id="YP_003097714.1" /db_xref="EnsemblGenomes-Gn:BSU12649" /db_xref="EnsemblGenomes-Tr:CAX52604" /db_xref="UniProtKB/Swiss-Prot:C0H3Z7" /translation="MSKDKQQKKAVHTKSREALFDTADLIKHAKELFGVKPDILQGAL FGVDQPRMTKSEANQLIQTFLTKEVMSS*" gene 1332187..1332405 /gene="ykzM" /locus_tag="BSU_12649" /old_locus_tag="BSU12649" CDS 1332402..1333802 /gene="xkdK" /locus_tag="BSU_12650" /old_locus_tag="BSU12650" /function="17.2: Prophage functions" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; Product type h: extrachromosomal origin" /codon_start=1 /transl_table=11 /product="phage PBSX; conserved hypothetical protein" /protein_id="NP_389147.2" /db_xref="EnsemblGenomes-Gn:BSU12650" /db_xref="EnsemblGenomes-Tr:CAB13122" /db_xref="InterPro:IPR020287" /db_xref="InterPro:IPR035089" /db_xref="InterPro:IPR035326" /db_xref="SubtiList:BG11546" /db_xref="UniProtKB/Swiss-Prot:P54331" /translation="MNGGTFTTGKEKERAGIYFNFKTTAQERVSLSERGTVALPVASS WGEAKTFVSISSVEDLNKKVGLSIDDPSLLLLREAKKNAKTVLMYRLTEGVRASADIA EGVKATAVYGGTKGNDIIIRINQNVLDANSFDVTTYMDESEVDKQTVKKAEELTANGY VTFTGTGDLSSTIPLTGSEGDTAAETLNASAGIRLSGGTDKAPVNSDYTDFLAAAETE SFDVIALPVAEGDQLKATFAAFIKRLRDGQGQKVQGVTANYAGDYEGIINVTEGVLLE DGTEVTPDKATAWVAGASAGATFNQSLTFVEYEGAVDVLHRLDHDTIVERLGKGEFLF TFDARDKSVSVEKDINSLVTFTAEKNKKFAKNKIVRVLDAVNNDLTRELKALIKSRKG SGSDIPASEDGLQYVKTMITQYMTTLQDAGGITGFDSDEDITISMNEDRDGFLIDLAV QPVDAAEKFYFNVEVN*" gene 1332402..1333802 /gene="xkdK" /locus_tag="BSU_12650" /old_locus_tag="BSU12650" CDS 1333804..1334247 /gene="xkdM" /locus_tag="BSU_12660" /old_locus_tag="BSU12660" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="phage PBSX; conserved hypothetical protein" /protein_id="NP_389148.1" /db_xref="EnsemblGenomes-Gn:BSU12660" /db_xref="EnsemblGenomes-Tr:CAB13123" /db_xref="InterPro:IPR018989" /db_xref="PDB:2GUJ" /db_xref="PDB:5LI2" /db_xref="SubtiList:BG11547" /db_xref="UniProtKB/Swiss-Prot:P54332" /translation="MALKAQNTISGKEGRLFLDGEEMAHIKTFEANVEKNKSEVNIMG RRMTGHKTTGANGTGTATFYKVTSKFVLLMMDYVKKGSDPYFTLQAVLDDQSSGRGTE RVTLYDVNFDSAKIASLDVDSEALEEEVPFTFEDFDVPEKLSDTF*" gene 1333804..1334247 /gene="xkdM" /locus_tag="BSU_12660" /old_locus_tag="BSU12660" S_feature 1334248..1334338 /Source="Nicolas_S_feature" /locus_tag="new_1334248_1334338" /HighExp="M40t90, HPh, LPh, MG 120, MG 150, MG 90, MG 60, Gly, dia0, LBGexp" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigK, Sig-" /TUshortPSig="0.999, 0" /TUlongSig="NA" /TUlongPSig="NA" /label="S457" CDS 1334339..1334785 /gene="xkdN" /locus_tag="BSU_12671" /old_locus_tag="BSU12671" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; Product type h: extrachromosomal origin" /codon_start=1 /transl_table=11 /product="phage PBSX; conserved hypothetical protein" /protein_id="NP_389149.2" /db_xref="EnsemblGenomes-Gn:BSU12671" /db_xref="EnsemblGenomes-Tr:CAB13124" /db_xref="InterPro:IPR014986" /db_xref="SubtiList:BG11548" /db_xref="UniProtKB/Swiss-Prot:P54333" /translation="MSEKNENVYDLSFFMPGKTIEAEEIKVPISKRFVDKKGNVIPFI LKPITTERIDELEKENTTFKNVKGRGRVKDLDSQRFYARIAIESTIYPDFRSKDLREA YKTADPVEVAKRVLSVGGEYANWLNKAIEINGFEDDLEDLEEEAKN*" gene 1334339..1334785 /gene="xkdN" /locus_tag="BSU_12671" /old_locus_tag="BSU12671" CDS 1334815..1334964 /gene="xkzB" /locus_tag="BSU_12672" /old_locus_tag="BSU12672" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; Product type h: extrachromosomal origin" /codon_start=1 /transl_table=11 /product="phage PBSX; conserved hypothetical protein" /protein_id="YP_003097715.1" /db_xref="EnsemblGenomes-Gn:BSU12672" /db_xref="EnsemblGenomes-Tr:CAX52605" /db_xref="UniProtKB/Swiss-Prot:C0H3Z8" /translation="MYYAMHELHYSPSQLLELYEAPKHFKALLFGLIGYKLDLLEKES RRGGN*" gene 1334815..1334964 /gene="xkzB" /locus_tag="BSU_12672" /old_locus_tag="BSU12672" CDS 1334966..1338964 /gene="xkdO" /locus_tag="BSU_12680" /old_locus_tag="BSU12680" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 20665904; Product type h: extrachromosomal origin" /codon_start=1 /transl_table=11 /product="phage PBSX; putative tape measure protein" /protein_id="NP_389150.2" /db_xref="EnsemblGenomes-Gn:BSU12680" /db_xref="EnsemblGenomes-Tr:CAB13125" /db_xref="InterPro:IPR008258" /db_xref="InterPro:IPR023346" /db_xref="SubtiList:BG11549" /db_xref="UniProtKB/Swiss-Prot:P54334" /translation="MAKLTARFDLEDKVSKKLKRIHKGFQEVEKKVKTINRQIKISIR AEDQAFYRLRKINDYIILKFAKSLEIKVVLDDQVTSKLDAIERKLKRLPKETKLTVSL VDRTAAAYKKIKKMLSNQKLSFLLIPDDKVTSTVKRIIGYIKKNLKNGYTVKLKVIDE ITKTVNRLTALLRKFEKTYYVKVVVKTKISDKINKKESLINKETSKKESDKSSDKGSD KNSDQKPGWVGKIKGWLKDWWTKSAWPWIKDTLNEIGKAFLDRFKERLIEKLKNDVFD KIIDKILGPQKKDDSGENSDTDKKVLNRNTGGNCCCDCCEGGISPGTKNKKTYRKKKS PTKAPNRTLKVPGEVIRRRQSGTPAESAPRTSGSKLKNWLGGLKSLGKDSSKLGKAFR GMGKAVPYVGSALAVFDLAGINKDNAGEKVGSIGGRIAGAEAGATAGAEAGATIGSFV GPEGTAIGGAIGGIGGGLVGGIGGEEAGKNIGKMFDTSKLKESISNSLFNKEWWSGKW NSISDTANGAITWIEDTWSKVSTWFDQYVFTPIYNVAVPVINFIVGLFAYAWDGILAV WNIVYPWFKDNVWDPISGAVTNVATTIWTGLCNAWTVISGIWSTVSTWFMDNVWNPVS EAVTTAATWIWSKINDAWTIISNIWTGVSNWFYDNVWNPIVKKVEDIKTSIKEKFDDA RKFFEDAWDGIETWFNEHVKDPLVKVSEKIAEKFQWLFDLKDSVGGFVAKVIHRGEEV THLKKKPIKKDSKEKKTSSKPTTNNIFAQSPSNNNMTVFQQALDQNATGGYITKPTIS WIGEAGKEFVIPVDNNRGRGKMLLSQAASKLGMQVVDDMGAASSSGGSPASVSGGAAV SPLSGTASPVMNTANLTGQASTLGQQFSEGFGKGISDQPVKMEDWKKKNINTPFTQMI SASPNYGKQMVSGYAKGQSGTATGTDGFLQSKVKTPFQATVSKSSSWGTGTVKGFAQG QNSTQTGTAQYVSTHVDKPFLRSKDTSNSWGSGLIGNFVTGMNSKSSEVKQAAKDMAK RVEQAFREELDIHSPSRVMMSLGRFASVGVVKGLDSVDVKKYAEKQAGSLAAAYSGMG AVGGNVKQWLMAAIMATKTPLSWLSGLMTIAQYESGGNPNSINLWDSNAKAGNPSQGL MQTVPTTFNAHKAPGMGNIRNPIHNAAAAIGYIKSRYGSIDNVPGIKSLKRGGPYVGY ANGGLITKEQIARVGEGNKREWIIPEERGIRGRYLLQRAAQALGMEVTDPSQSQQSEL SSGQVSAVTSASRPTAAVSGSKEIYIQFNGDQHFHNGQDAESLAAKIKQALIDELQKD INIGTKGVVAFD*" gene 1334966..1338964 /gene="xkdO" /locus_tag="BSU_12680" /old_locus_tag="BSU12680" promotor_-10 complement(1335370..1335388) /Source="Nicolas_upshift_promotors" /id="U1031" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp="0.975024975024975" /psig="0.975024975024975" /xcortree=2788 /SigmaFactorBS="gatgacctttagttttactgtgtatccgttTTTCAAATtttt cttaatataACCGATAATCCTTTTAACTgtagaagtaaccttgtcatctggaatcaaa a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1335379) /Source="Nicolas_upshifts" /id="U1031" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp="0.975024975024975" /psig="0.975024975024975" /xcortree=2788 /SigmaFactorBS="gatgacctttagttttactgtgtatccgttTTTCAAATtttt cttaatataACCGATAATCCTTTTAACTgtagaagtaaccttgtcatctggaatcaaa a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(1335402..1335409) /Source="Nicolas_upshift_promotors" /id="U1031" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp="0.975024975024975" /psig="0.975024975024975" /xcortree=2788 /SigmaFactorBS="gatgacctttagttttactgtgtatccgttTTTCAAATtttt cttaatataACCGATAATCCTTTTAACTgtagaagtaaccttgtcatctggaatcaaa a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 1336396 /Source="Nicolas_upshifts" /id="D695" /incds=1 /nref=1 /ntot=43 /MaxReadThrough="6.12795" /MaxDrop="2.89794" /score="11.201424" /energy="-12.1" /TU="U1029,U1030" /idTUdmin="U1030" /TUdmin="-6645" /isTUend="FALSE" promotor_-10 complement(1336610..1336622) /Source="Nicolas_upshift_promotors" /id="U1032" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.887112887112887" /psig="0.887112887112887" /xcortree=951 /SigmaFactorBS="aaccacgggtagacaatgttccatactgccaatatgccatcc caGGCATAGgcaaacaatcctaCTATAAAATTAATtacaggtacagcaacattatata t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1336626) /Source="Nicolas_upshifts" /id="U1032" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.887112887112887" /psig="0.887112887112887" /xcortree=951 /SigmaFactorBS="aaccacgggtagacaatgttccatactgccaatatgccatcc caGGCATAGgcaaacaatcctaCTATAAAATTAATtacaggtacagcaacattatata t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(1336636..1336642) /Source="Nicolas_upshift_promotors" /id="U1032" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.887112887112887" /psig="0.887112887112887" /xcortree=951 /SigmaFactorBS="aaccacgggtagacaatgttccatactgccaatatgccatcc caGGCATAGgcaaacaatcctaCTATAAAATTAATtacaggtacagcaacattatata t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" CDS 1338957..1339616 /gene="xkdP" /locus_tag="BSU_12690" /old_locus_tag="BSU12690" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type h : extrachromosomal origin" /codon_start=1 /transl_table=11 /product="phage PBSX; putative murein binding protein" /protein_id="NP_389151.2" /db_xref="EnsemblGenomes-Gn:BSU12690" /db_xref="EnsemblGenomes-Tr:CAB13126" /db_xref="InterPro:IPR018392" /db_xref="InterPro:IPR036779" /db_xref="SubtiList:BG11550" /db_xref="UniProtKB/Swiss-Prot:P54335" /translation="MTKSVYEFWISQGKDKLRLPVLPDQLSISNTVQNETVKVAKFGD LTFIDEQGAKEISFSSFFPKKYSPIAEYQNFPSPENAITKIEKWMKAKKPVQFLITGT KVNLTCSIEGFSYSEGQQDIGDRSFDIQLKEYKTASPRKIKQKKKTKAKRPSKAAPKT YTVKKGDTLWDIAGRFYGNSTQWRKIWNANKTAMIKRSKRNIRQPGHWIFPGQKLKIP Q*" gene 1338957..1339616 /gene="xkdP" /locus_tag="BSU_12690" /old_locus_tag="BSU12690" CDS 1339632..1340609 /gene="xkdQ" /locus_tag="BSU_12700" /old_locus_tag="BSU12700" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; Product type h: extrachromosomal origin" /codon_start=1 /transl_table=11 /product="phage PBSX; conserved hypothetical protein" /protein_id="NP_389152.1" /db_xref="EnsemblGenomes-Gn:BSU12700" /db_xref="EnsemblGenomes-Tr:CAB13127" /db_xref="SubtiList:BG11551" /db_xref="UniProtKB/Swiss-Prot:P54336" /translation="MIELFVIKDTEWLELVAESVSLEGHRYQAPRSIEATIVTKQGDQ TYYSVSEGDTVLFKWKGKELFRGIVFARTPDEHTLAFSAYDMLQYLVKNQDMYVFSNQ RADQIIRRIASDFQIPTTSIANTGHTIKSLVIKNDTTLYDIILKALKQTKSQTGRHYQ LYSEKGKLGLRAWPDPSEVWVLETGVNITGYQYSTSINDTATRVVLRRQKDNKTYKAS AKDSSGLNKYGVLQYTETVTDDINQAQLQQRADVRLAEKKGVKKELKNIQAVGIPEVQ SGLPVYISIPEAGIKKTYWVDTDRHEFKGTKHTMTIDVVEKNTMPEGVS*" gene 1339632..1340609 /gene="xkdQ" /locus_tag="BSU_12700" /old_locus_tag="BSU12700" CDS 1340609..1340875 /gene="xkdR" /locus_tag="BSU_12710" /old_locus_tag="BSU12710" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; Product type h: extrachromosomal origin" /codon_start=1 /transl_table=11 /product="phage PBSX; conserved hypothetical protein" /protein_id="NP_389153.1" /db_xref="EnsemblGenomes-Gn:BSU12710" /db_xref="EnsemblGenomes-Tr:CAB13128" /db_xref="InterPro:IPR022555" /db_xref="SubtiList:BG11552" /db_xref="UniProtKB/Swiss-Prot:P54337" /translation="MRLSEAIKHLAVGAVDAESPVELLPAEVVSVSPVEIKLKENSKL IIPEDAIIIPKRMQSGGDDALEPGDRLMTAALTGGQSFFILDKV*" gene 1340609..1340875 /gene="xkdR" /locus_tag="BSU_12710" /old_locus_tag="BSU12710" CDS 1340932..1341357 /gene="xkdS" /locus_tag="BSU_12720" /old_locus_tag="BSU12720" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; Product type h: extrachromosomal origin" /codon_start=1 /transl_table=11 /product="phage PBSX; conserved hypothetical protein" /protein_id="NP_389154.1" /db_xref="EnsemblGenomes-Gn:BSU12720" /db_xref="EnsemblGenomes-Tr:CAB13129" /db_xref="InterPro:IPR020288" /db_xref="SubtiList:BG11553" /db_xref="UniProtKB/Swiss-Prot:P54338" /translation="MALTPEVEFEDIEVESEVIETSQTYKIDFENGRITNELITGLEA IRQFVYIALQTERYAYSIYSHNVGNELQDVLTDHETTDAYKKMEIPRLIEEALVYDDR ISAVTDFEIEKQGDAFHVSFVVETDEGTLEIEEVIGEDV*" gene 1340932..1341357 /gene="xkdS" /locus_tag="BSU_12720" /old_locus_tag="BSU12720" CDS 1341350..1342396 /gene="xkdT" /locus_tag="BSU_12730" /old_locus_tag="BSU12730" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 18077713; Product type h: extrachromosomal origin" /codon_start=1 /transl_table=11 /product="phage PBSX; putative base plate assembly protein" /protein_id="NP_389155.1" /db_xref="EnsemblGenomes-Gn:BSU12730" /db_xref="EnsemblGenomes-Tr:CAB13130" /db_xref="InterPro:IPR006949" /db_xref="SubtiList:BG11554" /db_xref="UniProtKB/Swiss-Prot:P54339" /translation="MFEDQTFEAIMERMLNSISADIDTREGSVIYNALAPAAAELAKS YIWLDTVLELVFSDTAQGEFLDRRAAEAGIERTAATKAVRAGEFTSGVTIPVGSRFYV DNLYFQYTADGTLICETPGEAGNANLTGRNLLSLDTIPGLETAIVKEILIPGREEEGD DSLRERYFTRVRREAVSANKMHYKEWAEEVDGVGKAKIFPLWNGEGTVKIVVTNANLE PASPILIQKVKDYIDPEPGQGEGQAPIGAVVTVESAVWKEVEISAEVLPEINHSIDEV KSEIEEGVLNFFKKMAFEDNVIRLSQINNIVYNSPSVSDYSNIQINGTSENLVLSDVE IPKLGQVKIIEQTR*" gene 1341350..1342396 /gene="xkdT" /locus_tag="BSU_12730" /old_locus_tag="BSU12730" CDS 1342380..1342958 /gene="xkdU" /locus_tag="BSU_12740" /old_locus_tag="BSU12740" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; Product type h: extrachromosomal origin" /codon_start=1 /transl_table=11 /product="phage PBSX; conserved hypothetical protein" /protein_id="NP_389156.1" /db_xref="EnsemblGenomes-Gn:BSU12740" /db_xref="EnsemblGenomes-Tr:CAB13131" /db_xref="InterPro:IPR018755" /db_xref="SubtiList:BG11555" /db_xref="UniProtKB/Swiss-Prot:P54340" /translation="MSKQDDMRAYLPPFLTSLKEMAELLKAEAPEFDKQNDSIFDLTD QLFVPTATWGLSRWEKILNVPRESGDTDEIRRLRLISKMSNIPPITYRAIEQAVNRFL KNPSAQVRLLPGEYRFNVDINVDDLQHMNELIEAIENMKPAHLAYTLRGGLNETLRIK DTVILNHRRYRTASELKVGYSVTLNNNEVVLT*" gene 1342380..1342958 /gene="xkdU" /locus_tag="BSU_12740" /old_locus_tag="BSU12740" CDS 1342955..1343227 /gene="xkzA" /locus_tag="BSU_12749" /old_locus_tag="BSU12749" /function="18: Unknown function" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; Product type h: extrachromosomal origin" /codon_start=1 /transl_table=11 /product="phage PBSX; conserved hypothetical protein" /protein_id="YP_003097716.1" /db_xref="EnsemblGenomes-Gn:BSU12749" /db_xref="EnsemblGenomes-Tr:CAX52606" /db_xref="UniProtKB/Swiss-Prot:C0H3Z9" /translation="MISTIYRERTAADLKSRIDHVLLNGQKTEIVELAIDGATVTVLT KREEDIKHIETVQIFDELGNVITERKTDLDVSENRTLDFRFTFEVV*" gene 1342955..1343227 /gene="xkzA" /locus_tag="BSU_12749" /old_locus_tag="BSU12749" CDS 1343230..1345293 /gene="xkdV" /locus_tag="BSU_12750" /old_locus_tag="BSU12750" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; Product type h: extrachromosomal origin" /codon_start=1 /transl_table=11 /product="phage PBSX; conserved hypothetical protein" /protein_id="NP_389158.1" /db_xref="EnsemblGenomes-Gn:BSU12750" /db_xref="EnsemblGenomes-Tr:CAB13132" /db_xref="InterPro:IPR008983" /db_xref="SubtiList:BG11556" /db_xref="UniProtKB/Swiss-Prot:P54341" /translation="MAYEEKTDWLPDDPINEDDVNRWEKGIKDAHTDLAAHKNDMNNP HNTTKAQIGLGNVDNVQQASKTEFNEHNHDSTRHITSVERDEWNAKETPAGAQYKADQ AEANAKAYTDNFAARRDNPNQVTKAQVGLGNVENVKQASLADFDAHLSNSKVHVSEGE RNKWNAAQLIKLTGDDGKRIQLQDGTDILTLSSGFYCAVGQSVVNNPVEGDAAWYNYD IVEGGSGRKTIVAYQSWGSMMWIGMVHTDGEFRGWKQIATTDFIDRVQTELDLHENDK TNPHSVTKQQVGLGNVENVKQETPDGAQKKADTALNQSKDYTNSTAFITRPLNSITDA NDLNLPPGTYRLDTNYMNANPVLQNQFPLNDNRTGLLIIYPSANKWATRQDWFSISTK TLYTRVAVNGTDYSGWYILENSEGSQNKADKALADAKNYVETNYTNQKLTVLTGSNAI QDARISGNDYKYGITFMDIGANNTTGYPLTYGFVKNEKHSNYRFTQYFYGNADTTSGS YDHVGTWIRHWWADSGWTAWQKISGFAHANIGTTGRQALIKGENNKIKYNRIIKDSHK LFDTKNNRFVASHAGMHLVSASLYIENTERYSNFELYVYVNGTKYKLMNQFRMPTPSN NSDNEFNATVTGSVTVPLDAGDYVEIYVYVGYSGDVTRYVTDSNGALNYFDVLELGGR NYPRV*" gene 1343230..1345293 /gene="xkdV" /locus_tag="BSU_12750" /old_locus_tag="BSU12750" CDS 1345305..1345634 /gene="xkdW" /locus_tag="BSU_12760" /old_locus_tag="BSU12760" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; Product type h: extrachromosomal origin" /codon_start=1 /transl_table=11 /product="phage PBSX; conserved hypothetical protein" /protein_id="NP_389159.1" /db_xref="EnsemblGenomes-Gn:BSU12760" /db_xref="EnsemblGenomes-Tr:CAB13133" /db_xref="InterPro:IPR019094" /db_xref="InterPro:IPR035950" /db_xref="PDB:2HG7" /db_xref="SubtiList:BG11557" /db_xref="UniProtKB/Swiss-Prot:P54342" /translation="MILYDAIMYKYPNAVSRKDFELRNDGNGSYIEKWNLRAPLPTQA ELETWWEELQKNPPYEPPDQVELLAQELSQEKLARKQLEELNKTLGNELSDIKLSLLS LKGDYAE*" gene 1345305..1345634 /gene="xkdW" /locus_tag="BSU_12760" /old_locus_tag="BSU12760" CDS 1345631..1345795 /gene="xkdX" /locus_tag="BSU_12770" /old_locus_tag="BSU12770" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; Product type h: extrachromosomal origin" /codon_start=1 /transl_table=11 /product="phage PBSX; conserved hypothetical protein" /protein_id="NP_389160.1" /db_xref="EnsemblGenomes-Gn:BSU12770" /db_xref="EnsemblGenomes-Tr:CAB13134" /db_xref="InterPro:IPR010022" /db_xref="SubtiList:BG11558" /db_xref="UniProtKB/Swiss-Prot:P54343" /translation="MNYWVLALYYEWATTDMVKQALAYEDCSIQDLAEGVNKKLITAD QYKEITGKAM*" gene 1345631..1345795 /gene="xkdX" /locus_tag="BSU_12770" /old_locus_tag="BSU12770" CDS 1345839..1346678 /gene="xepA" /locus_tag="BSU_12780" /old_locus_tag="BSU12780" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:7921239, 9555893" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7921239, 9555893; Product type h: extrachromosomal origin" /codon_start=1 /transl_table=11 /product="phage PBSX; lytic exoenzyme" /protein_id="NP_389161.2" /db_xref="EnsemblGenomes-Gn:BSU12780" /db_xref="EnsemblGenomes-Tr:CAB13135" /db_xref="SubtiList:BG10959" /db_xref="UniProtKB/Swiss-Prot:P39797" /translation="MVKYQYEFPLDKAGKAGAVKPYRGGKNDFVTPVSNLSGVAEILT NAALKATEAYSQLGQDRLGAVLISKVKGWAYADREGTLFIEESDNNNVWTTTAAVNVA AGVLTATDWVYLSKRYYRFRYVNGNLQQSEFVLYQSVGAGEMDVRVNEKTPLQIDFAE NQTHDGRLKVEARKTFDFVFHENAESASEGAALPVDGAAHLLVEVYGTAEMSEVKFWG KSVSGQKLPIRGVKTDDATTASSTLGKAEAWAFDIKGFKEIIMEIISITGGTLSVKGT AVS*" gene 1345839..1346678 /gene="xepA" /locus_tag="BSU_12780" /old_locus_tag="BSU12780" misc_feature 1346685..1346703 /Source="Nicolas_upshift_promotors" /id="U1033" /multdbtbs="-" /comp="M12" /sig="Sig-" /pcomp="0.892107892107892" /psig="0.018981018981019" /xcortree=1520 /SigmaFactorBS="tatcaccggcggtactctttcggtaaaagggaccgcggtttc ataatagtctCGGCCCTCGGAAGGGAGGTgatctgcatgtgaaggaggagtgagagat g" /listShort="xhlA, xhlB, xlyA" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 1346693 /Source="Nicolas_upshifts" /id="U1033" /multdbtbs="-" /comp="M12" /sig="Sig-" /pcomp="0.892107892107892" /psig="0.018981018981019" /xcortree=1520 /SigmaFactorBS="tatcaccggcggtactctttcggtaaaagggaccgcggtttc ataatagtctCGGCCCTCGGAAGGGAGGTgatctgcatgtgaaggaggagtgagagat g" /listShort="xhlA, xhlB, xlyA" /GFF_Attribute="listLong" CDS 1346731..1347000 /gene="xhlA" /locus_tag="BSU_12790" /old_locus_tag="BSU12790" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:7921239, 9555893, 22720735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7921239, 9555893, 22720735; Product type h: extrachromosomal origin" /codon_start=1 /transl_table=11 /product="phage PBSX; putative enzyme" /protein_id="NP_389162.1" /db_xref="EnsemblGenomes-Gn:BSU12790" /db_xref="EnsemblGenomes-Tr:CAB13136" /db_xref="GOA:P39798" /db_xref="InterPro:IPR019715" /db_xref="SubtiList:BG10960" /db_xref="UniProtKB/Swiss-Prot:P39798" /translation="MQQEADVNVFQQDLADMKGEHKALEQRVSALERVSDRQDQQIMT LNEKLNKIEENTTWIKRTITGAIITAVSTGIIGGAIAIMYSLLQH*" gene 1346731..1347000 /gene="xhlA" /locus_tag="BSU_12790" /old_locus_tag="BSU12790" CDS 1347013..1347276 /gene="xhlB" /locus_tag="BSU_12800" /old_locus_tag="BSU12800" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:2110147, 9555893" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 2110147, 9555893; Product type h: extrachromosomal origin" /codon_start=1 /transl_table=11 /product="phage PBSX; holin" /protein_id="NP_389163.1" /db_xref="EnsemblGenomes-Gn:BSU12800" /db_xref="EnsemblGenomes-Tr:CAB13137" /db_xref="GOA:Q99163" /db_xref="InterPro:IPR006479" /db_xref="SubtiList:BG10961" /db_xref="UniProtKB/Swiss-Prot:Q99163" /translation="MNTFDKGTVIRTVLLLIALINQTMLMLGKSPLDIQEEQVNQLAD ALYSAGSIAFTIGTTLAAWFKNNYVTEKGKKQRDLLRDNNLTK*" gene 1347013..1347276 /gene="xhlB" /locus_tag="BSU_12800" /old_locus_tag="BSU12800" CDS 1347289..1348182 /gene="xlyA" /locus_tag="BSU_12810" /old_locus_tag="BSU12810" /EC_number="3.5.1.28" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:7921239, 9555893" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7921239, 9555893; Product type h: extrachromosomal origin" /codon_start=1 /transl_table=11 /product="phage PBSX; N-acetylmuramoyl-L-alanine amidase" /protein_id="NP_389164.1" /db_xref="EnsemblGenomes-Gn:BSU12810" /db_xref="EnsemblGenomes-Tr:CAB13138" /db_xref="GOA:P39800" /db_xref="InterPro:IPR002477" /db_xref="InterPro:IPR002502" /db_xref="InterPro:IPR018392" /db_xref="InterPro:IPR036365" /db_xref="InterPro:IPR036366" /db_xref="InterPro:IPR036505" /db_xref="InterPro:IPR036779" /db_xref="PDB:3HMB" /db_xref="PDB:3RDR" /db_xref="SubtiList:BG10962" /db_xref="UniProtKB/Swiss-Prot:P39800" /translation="MVNIIQDFIPVGANNRPGYAMTPLYITVHNTANTAVGADAAAHA RYLKNPDTTTSWHFTVDDTEIYQHLPLNENGWHAGDGNGSGNRASIGIEICENADGDF AKATANAQWLIKTLMAEHNISLANVVPHKYWSGKECPRKLLDTWDSFKAGIGGGGSQT YVVKQGDTLTSIARAFGVTVAQLQEWNNIEDPNLIRVGQVLIVSAPSAAEKPELYPLP DGIIQLTTPYTSGEHVFQVQRALAALYFYPDKGAVNNGIDGVYGPKTADAVARFQSVN GLTADGIYGPATKEKIAAQLS*" gene 1347289..1348182 /gene="xlyA" /locus_tag="BSU_12810" /old_locus_tag="BSU12810" downshifts 1348191 /Source="Nicolas_upshifts" /id="D696" /incds=0 /nref=29 /ntot=162 /MaxReadThrough="3.77255" /MaxDrop="5.00305" /score="30.9009227" /energy="-12.5" /TU="U1029,U1033" /idTUdmin="U1029" /TUdmin="-152" /isTUend="FALSE" S_feature complement(1348200..1348403) /Source="Nicolas_S_feature" /locus_tag="new_1348200_1348403_c" /HighExp="S8, S6, S7, BT, B36, S5, S4, G/S, Pyr, B60" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigEF" /TUshortPSig="1, 0.798" /TUlongSig="NA" /TUlongPSig="NA" /label="S458" CDS complement(1348219..1348356) /gene="spoIISC" /locus_tag="BSU_12815" /old_locus_tag="BSU12815" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1c: Function from experimental evidences in the studied genus; PubMedId: 11371520, 18096016, 20863891, 21147767, 25039482, 26300872, 27294956; Product type r: regulator" /codon_start=1 /transl_table=11 /product="three component toxin / antitoxin / antitoxin SpoIISABC, antitoxin C" /protein_id="YP_009513952.1" /translation="MSGDTVKKLVRRVKFVDYGRFGLSGYSLRVRERSAGIIKKLKKK K*" gene complement(1348219..1348356) /gene="spoIISC" /locus_tag="BSU_12815" /old_locus_tag="BSU12815" downshifts complement(1348243) /Source="Nicolas_upshifts" /id="D697" /incds=0 /nref=31 /ntot=215 /MaxReadThrough="2.75573" /MaxDrop="4.3776" /score="24.0186344" /energy="-12.5" /TU="U1034" /idTUdmin="U1035" /TUdmin=0 /isTUend="TRUE" CDS complement(1348442..1348612) /gene="spoIISB" /locus_tag="BSU_12820" /old_locus_tag="BSU12820" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:11371520, 18096016, 20863891, 21147767, 25039482, 26300872, 27294956" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11371520, 18096016, 20863891, 21147767, 25039482, 26300872, 27294956; Product type f: factor" /codon_start=1 /transl_table=11 /product="three-component apoptotic control system component B (antitoxin B)" /protein_id="NP_389165.1" /db_xref="EnsemblGenomes-Gn:BSU12820" /db_xref="EnsemblGenomes-Tr:CAB13139" /db_xref="GOA:O34800" /db_xref="InterPro:IPR025897" /db_xref="PDB:3O6Q" /db_xref="SubtiList:BG12678" /db_xref="UniProtKB/Swiss-Prot:O34800" /translation="MERAFQNRCEPRAAKPFKILKKRSTTSVASYQVSPHTARIFKEN ERLIDEYKRKKA*" gene complement(1348442..1348612) /gene="spoIISB" /locus_tag="BSU_12820" /old_locus_tag="BSU12820" downshifts complement(1348448) /Source="Nicolas_upshifts" /id="D698" /incds=0 /nref=6 /ntot=86 /MaxReadThrough="4.69899" /MaxDrop="3.0872" /score="24.0186344" /energy="-12.5" /TU="U1034,U1035" /idTUdmin="U1035" /TUdmin="-205" /isTUend="FALSE" CDS complement(1348612..1349358) /gene="spoIISA" /locus_tag="BSU_12830" /old_locus_tag="BSU12830" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:11371520, 18096016, 20863891, 21147767, 25039482, 26300872, 27294956" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11371520, 18096016, 20863891, 21147767, 25039482, 26300872, 27294956; Product type f: factor" /codon_start=1 /transl_table=11 /product="three-component apoptosis factor (ABC toxin/antitoxin/antitoxin system)" /protein_id="NP_389166.1" /db_xref="EnsemblGenomes-Gn:BSU12830" /db_xref="EnsemblGenomes-Tr:CAB13140" /db_xref="GOA:O34853" /db_xref="InterPro:IPR025940" /db_xref="PDB:3O6Q" /db_xref="SubtiList:BG12677" /db_xref="UniProtKB/Swiss-Prot:O34853" /translation="MVLFFQIMVWCIVAGLGLYVYATWRFEAKVKEKMSAIRKTWYLL FVLGAMVYWTYEPTSLFTHWERYLIVAVSFALIDAFIFLSAYVKKLAGSELETDTREI LEENNEMLHMYLNRLKTYQYLLKNEPIHVYYGSIDAYAEGIDKLLKTYADKMNLTASL CHYSTQADKDRLTEHMDDPADVQTRLDRKDVYYDQYGKVVLIPFTIETQNYVIKLTSD SIVTEFDYLLFTSLTSIYDLVLPIEEEGEG*" gene complement(1348612..1349358) /gene="spoIISA" /locus_tag="BSU_12830" /old_locus_tag="BSU12830" promotor_-10 complement(1349193..1349212) /Source="Nicolas_upshift_promotors" /id="U1034" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.724275724275724" /psig=1 /xcortree=623 /SigmaFactorBS="tcaaagaaaaaatgtccgccattcggaaaacttggTATTTGC TgtttgttctgggcgcTATGGTATACTGGACATATGagcccacttccctatttaccca c" /listShort="spoIISB, S458" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1349210) /Source="Nicolas_upshifts" /id="U1034" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.724275724275724" /psig=1 /xcortree=623 /SigmaFactorBS="tcaaagaaaaaatgtccgccattcggaaaacttggTATTTGC TgtttgttctgggcgcTATGGTATACTGGACATATGagcccacttccctatttaccca c" /listShort="spoIISB, S458" /GFF_Attribute="listLong" promotor_-35 complement(1349228..1349235) /Source="Nicolas_upshift_promotors" /id="U1034" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.724275724275724" /psig=1 /xcortree=623 /SigmaFactorBS="tcaaagaaaaaatgtccgccattcggaaaacttggTATTTGC TgtttgttctgggcgcTATGGTATACTGGACATATGagcccacttccctatttaccca c" /listShort="spoIISB, S458" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(1349384..1349402) /Source="Nicolas_upshift_promotors" /id="U1035" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.798201798201798" /psig="0.798201798201798" /xcortree=1112 /SigmaFactorBS="cttctgtcaaaggagcggtttttttgatggaacaGGAAAAcc atccggatctctcGAATACAATAAGCAGAACCtatttcagatgtgagggattcgaata t" /listShort="spoIISA, spoIISB, S458" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1349397) /Source="Nicolas_upshifts" /id="U1035" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.798201798201798" /psig="0.798201798201798" /xcortree=1112 /SigmaFactorBS="cttctgtcaaaggagcggtttttttgatggaacaGGAAAAcc atccggatctctcGAATACAATAAGCAGAACCtatttcagatgtgagggattcgaata t" /listShort="spoIISA, spoIISB, S458" /GFF_Attribute="listLong" promotor_-35 complement(1349418..1349423) /Source="Nicolas_upshift_promotors" /id="U1035" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.798201798201798" /psig="0.798201798201798" /xcortree=1112 /SigmaFactorBS="cttctgtcaaaggagcggtttttttgatggaacaGGAAAAcc atccggatctctcGAATACAATAAGCAGAACCtatttcagatgtgagggattcgaata t" /listShort="spoIISA, spoIISB, S458" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(1349468..1350469) /gene="pitB" /locus_tag="BSU_12840" /old_locus_tag="BSU12840" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2b: Function from indirect experimental evidences (e.g. phenotypes); PubMedId: 10784039, 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative low-affinity inorganic phosphate transporter" /protein_id="NP_389167.2" /db_xref="EnsemblGenomes-Gn:BSU12840" /db_xref="EnsemblGenomes-Tr:CAB13141" /db_xref="GOA:O34436" /db_xref="InterPro:IPR001204" /db_xref="SubtiList:BG13226" /db_xref="UniProtKB/Swiss-Prot:O34436" /translation="MDILLILTILIVICALAFDFINGFHDTANAIATSVSTKALKPRH AIILAAVMNFVGAMTFTGVAKTITKDIVDPYTLENGSVVILAALLAAIAWNLITWYYG IPSSSSHAIIGAIAGAAIAAAGFAALNYKGFIKIIEALILSPIIAFVLGFILYSIVKL IFKDSNLAKTNKQFRRVQIVTAALQSYTHGTNDAQKAMGIITMALITANLHTSANDIP TWVQFACATAMGLGTSIGGWKIIKTVGGKIMKIRPVNGVSADLTGAAIIFGATFIHLP VSTTHVISSSILGVGASHRVKGVNWGTAKRMLITWVITLPISATLGAIAYFILNMIF* " gene complement(1349468..1350469) /gene="pitB" /locus_tag="BSU_12840" /old_locus_tag="BSU12840" downshifts complement(1349497) /Source="Nicolas_upshifts" /id="D699" /incds=0 /nref=205 /ntot=253 /MaxReadThrough="3.49591" /MaxDrop="5.81942" /score="21.8061263" /energy="-11" /TU="U1036,U1038" /idTUdmin="U1037" /TUdmin=0 /isTUend="TRUE" CDS complement(1350482..1351099) /gene="ykaA" /locus_tag="BSU_12850" /old_locus_tag="BSU12850" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 9696772, 14563871; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative PitB transporter accessory protein" /protein_id="NP_389168.1" /db_xref="EnsemblGenomes-Gn:BSU12850" /db_xref="EnsemblGenomes-Tr:CAB13142" /db_xref="InterPro:IPR018445" /db_xref="SubtiList:BG13225" /db_xref="UniProtKB/Swiss-Prot:O34454" /translation="MIRRKKDKFSLLLTEIAKNIDETAEYFVNFKVTNQTTLKEFADT LKEYETKGDNHVHVMIKELNKAFITPIEREDILQLTNSLDDVLDGIEHFSAMMEIFSI TSSDEHIDKFSGYIRECAKEILITIELLAENRLKDIQPHAIKIKEYEHSCDNLHRKSL KNLFGNETDPIKVIQYREIYETLEEIADSCQSVANNLETIIMKNA*" gene complement(1350482..1351099) /gene="ykaA" /locus_tag="BSU_12850" /old_locus_tag="BSU12850" promotor_-10 complement(1351135..1351154) /Source="Nicolas_upshift_promotors" /id="U1036" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.933066933066933" /psig="0.996003996003996" /xcortree=2607 /SigmaFactorBS="aagatacgtttttttcgactttaCCTGTtttttttcgacaaa aGGCTATATAATAATTTGATGtgtgcattgttcattcaaactatggagggtttttaat g" /listShort="ykaA, pit" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1351137) /Source="Nicolas_upshifts" /id="U1036" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.933066933066933" /psig="0.996003996003996" /xcortree=2607 /SigmaFactorBS="aagatacgtttttttcgactttaCCTGTtttttttcgacaaa aGGCTATATAATAATTTGATGtgtgcattgttcattcaaactatggagggtttttaat g" /listShort="ykaA, pit" /GFF_Attribute="listLong" S_feature complement(1351139..1351236) /Source="Nicolas_S_feature" /locus_tag="new_1351139_1351236_c" /HighExp="H2O2, Etha, dia15, Diami, Paraq, Heat, dia5, Salt, LBGstat, Oxctl" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="0.972, 0.987" /TUlongSig="SigA" /TUlongPSig="0.992" /label="S459" promotor_-35 complement(1351170..1351174) /Source="Nicolas_upshift_promotors" /id="U1036" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.933066933066933" /psig="0.996003996003996" /xcortree=2607 /SigmaFactorBS="aagatacgtttttttcgactttaCCTGTtttttttcgacaaa aGGCTATATAATAATTTGATGtgtgcattgttcattcaaactatggagggtttttaat g" /listShort="ykaA, pit" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(1351216..1351235) /Source="Nicolas_upshift_promotors" /id="U1037" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.962037962037962" /psig="0.972027972027972" /xcortree=641 /SigmaFactorBS="atatactttttacgttaagcagaaagtttttgcaaacttGGG TCGTTtttttaaagcgaagTAGGTCAAAATAAGGAGACAcgatttatcaaaaaagtca a" /listShort="S459, ykaA, pit" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1351236) /Source="Nicolas_upshifts" /id="U1037" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.962037962037962" /psig="0.972027972027972" /xcortree=641 /SigmaFactorBS="atatactttttacgttaagcagaaagtttttgcaaacttGGG TCGTTtttttaaagcgaagTAGGTCAAAATAAGGAGACAcgatttatcaaaaaagtca a" /listShort="S459, ykaA, pit" /GFF_Attribute="listLong" promotor_-35 complement(1351250..1351257) /Source="Nicolas_upshift_promotors" /id="U1037" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.962037962037962" /psig="0.972027972027972" /xcortree=641 /SigmaFactorBS="atatactttttacgttaagcagaaagtttttgcaaacttGGG TCGTTtttttaaagcgaagTAGGTCAAAATAAGGAGACAcgatttatcaaaaaagtca a" /listShort="S459, ykaA, pit" /GFF_Attribute="listLong" /label="promotor_-35" misc_feature complement(1351281..1351300) /Source="Nicolas_upshift_promotors" /id="U1038" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.677322677322677" /psig="0.987012987012987" /xcortree=1829 /SigmaFactorBS="ggaaccgttttttggtgaaacagaagataaaagttgacagga aaaacacaactTTTGATATACTTTTTACGTTaagcagaaagtttttgcaaacttgggt c" /listShort="S459, ykaA, pit" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(1351293) /Source="Nicolas_upshifts" /id="U1038" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.677322677322677" /psig="0.987012987012987" /xcortree=1829 /SigmaFactorBS="ggaaccgttttttggtgaaacagaagataaaagttgacagga aaaacacaactTTTGATATACTTTTTACGTTaagcagaaagtttttgcaaacttgggt c" /listShort="S459, ykaA, pit" /GFF_Attribute="listLong" CDS complement(1351375..1352691) /gene="steT" /locus_tag="BSU_12860" /old_locus_tag="BSU12860" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:15849754, 16850406, 17344220, 19419962, 20610400" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15849754, 16850406, 17344220, 19419962, 20610400; Product type t : transporter" /codon_start=1 /transl_table=11 /product="serine / threonine exchanger" /protein_id="NP_389169.1" /db_xref="EnsemblGenomes-Gn:BSU12860" /db_xref="EnsemblGenomes-Tr:CAB13143" /db_xref="GOA:O34739" /db_xref="InterPro:IPR002293" /db_xref="SubtiList:BG13227" /db_xref="UniProtKB/Swiss-Prot:O34739" /translation="MHTEDNGLKKEIGLLFALTLVIGTIIGSGVFMKPGAVLAYSGDS KMALFAWLLGGILTLAGGLTIAEIGTQIPKTGGLYTYLEEVYGEFWGFLCGWVQIIIY GPAIIGALGLYFGSLMANLFGWGSGLSKVIGIIAVLFLCVINIIGTKYGGFVQTLTTI GKLIPIACIIVFGLWKGDQHIFTAVNESISDMNFGAAILATLFAYDGWILLAALGGEM KNPEKLLPRAMTGGLLIVTAIYIFINFALLHILSANEIVTLGENATSTAATMLFGSIG GKLISVGIIVSIFGCLNGKVLSFPRVSFAMAERKQLPFAEKLSHVHPSFRTPWIAISF QIALALIMMLISNPDKLSEISIFMIYIFYVMAFFAVFILRKRAKGEKRAYSVPLYPFM PILAIAGSFFVLGSTLITDTMSCGLSILIGLAGLPVYYGMKKRKAS*" gene complement(1351375..1352691) /gene="steT" /locus_tag="BSU_12860" /old_locus_tag="BSU12860" downshifts complement(1351390) /Source="Nicolas_upshifts" /id="D700" /incds=0 /nref=3 /ntot=92 /MaxReadThrough="3.59461" /MaxDrop="3.97157" /score="23.3119204" /energy="-14.4" /TU="U1039" /idTUdmin="U1039" /TUdmin="-88" /isTUend="FALSE" promotor_-10 complement(1352738..1352757) /Source="Nicolas_upshift_promotors" /id="U1039" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.633366633366633" /psig="0.992007992007992" /xcortree=2632 /SigmaFactorBS="gtacacaaagcaaatttcgaaaatcagaaaatttattttATT TcacttttctaaaatAGGGTTTACAATATGAAAAAatagattcttcaacatgaagctt c" /listShort="ykbA" /listLong="S459, ykaA, pit" /label="promotor_-10" upshifts complement(1352754) /Source="Nicolas_upshifts" /id="U1039" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.633366633366633" /psig="0.992007992007992" /xcortree=2632 /SigmaFactorBS="gtacacaaagcaaatttcgaaaatcagaaaatttattttATT TcacttttctaaaatAGGGTTTACAATATGAAAAAatagattcttcaacatgaagctt c" /listShort="ykbA" /listLong="S459, ykaA, pit" promotor_-35 complement(1352772..1352775) /Source="Nicolas_upshift_promotors" /id="U1039" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.633366633366633" /psig="0.992007992007992" /xcortree=2632 /SigmaFactorBS="gtacacaaagcaaatttcgaaaatcagaaaatttattttATT TcacttttctaaaatAGGGTTTACAATATGAAAAAatagattcttcaacatgaagctt c" /listShort="ykbA" /listLong="S459, ykaA, pit" /label="promotor_-35" promotor_-35 1352974..1352981 /Source="Nicolas_upshift_promotors" /id="U1040" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.774225774225774" /psig="0.964035964035964" /xcortree=632 /SigmaFactorBS="tgaacgaaccttcggtgaagctgataTGTTGACTttctcatg cgaataAAATACTTTGTTATTAGAACaataaatatacaattatgatatgatatctcga a" /listShort="S460, mhqA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1352996..1353015 /Source="Nicolas_upshift_promotors" /id="U1040" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.774225774225774" /psig="0.964035964035964" /xcortree=632 /SigmaFactorBS="tgaacgaaccttcggtgaagctgataTGTTGACTttctcatg cgaataAAATACTTTGTTATTAGAACaataaatatacaattatgatatgatatctcga a" /listShort="S460, mhqA" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 1353008..1353079 /Source="Nicolas_S_feature" /locus_tag="new_1353008_1353079" /HighExp="Etha, dia15, Salt, Heat, dia5, Diami, H2O2, M9-stat, MG 25, BMM" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.964" /TUlongSig="NA" /TUlongPSig="NA" /label="S460" upshifts 1353008 /Source="Nicolas_upshifts" /id="U1040" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.774225774225774" /psig="0.964035964035964" /xcortree=632 /SigmaFactorBS="tgaacgaaccttcggtgaagctgataTGTTGACTttctcatg cgaataAAATACTTTGTTATTAGAACaataaatatacaattatgatatgatatctcga a" /listShort="S460, mhqA" /GFF_Attribute="listLong" CDS 1353080..1354030 /gene="mhqA" /locus_tag="BSU_12870" /old_locus_tag="BSU12870" /EC_number="1.13.11.-" /function="16.11: Scavenge (Catabolism)" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:17407181, 17725564" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 17407181, 17725564; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="hydroquinone-specific extradiol dioxygenase" /protein_id="NP_389170.1" /db_xref="EnsemblGenomes-Gn:BSU12870" /db_xref="EnsemblGenomes-Tr:CAB13144" /db_xref="GOA:O34689" /db_xref="InterPro:IPR004360" /db_xref="InterPro:IPR029068" /db_xref="SubtiList:BG13228" /db_xref="UniProtKB/Swiss-Prot:O34689" /translation="MKVNGIHHVSALTADAQKNLDFYKKVLGLKLVKKSVNQDEPTMY HLFYGDEVANPGTELTFFEIPRIAPFHAGTNSISSIGLRVPGTEALHYWKERFEEQQV THSGISKRAGRDILAFQDHEGQRLVLTADEEGKGYGLPVKQSGIPEEFSFRGLGPVEL TVPYAEPTLHVLTNILGFTEISREPVEGQGTAVILESGEGGAATEIHLIERNDLPRER QGKGSVHHVAFRVRDEEELAGWHRIISREGFSNSGIVERYYFKALYFREPNGILFELS TDGPGFMVDENLDELGQTIALPPYLEHRRAEIEAKLKPIQ*" gene 1353080..1354030 /gene="mhqA" /locus_tag="BSU_12870" /old_locus_tag="BSU12870" downshifts 1354018 /Source="Nicolas_upshifts" /id="D701" /incds=0 /nref=95 /ntot=231 /MaxReadThrough="0.70251" /MaxDrop="5.11652" /score="51.2936135" /energy="-17.5" /TU="NA" /idTUdmin="U1040" /TUdmin="-2" /isTUend="TRUE" CDS 1354131..1354277 /locus_tag="BSU_12875" /old_locus_tag="BSU12875" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_009513953.1" /translation="MLIGRNGLKPFANMGDWYGMASAKILSLFINSLFIFACYTISKL DKKE*" gene 1354131..1354277 /locus_tag="BSU_12875" /old_locus_tag="BSU12875" CDS 1354285..1356435 /gene="ykcB" /locus_tag="BSU_12880" /old_locus_tag="BSU12880" /EC_number="2.4.1.-" /function="16.13: Shape" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406, 18175906; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative membrane glycosyl transferase" /protein_id="NP_389171.2" /db_xref="EnsemblGenomes-Gn:BSU12880" /db_xref="EnsemblGenomes-Tr:CAB13145" /db_xref="GOA:O34575" /db_xref="SubtiList:BG13229" /db_xref="UniProtKB/Swiss-Prot:O34575" /translation="MEKKKRELDIVLLLILLASAFLNIYNIWKDDTVNPYYTAAVTSM MQSFHNFFYASFDAAGFITVDKPPVTYQIQTISALIFGMHGWSVILPQALAGVGSVLL MYLLIKPTFGKTAARIASFVMACTPIAVAVARTNNVDALLVFFLLLATWLLFKAIRKG KLIWLLAAFFVVGVGFNTKMLQAYMILPAFLLFYLIAANATIKKKIVSLVSALAVLAA VSLSWPLIVDNIPASKRPYIGSSQTNSVLELAFGYNGIQRLTGQNSGGGQGAPNKDAS KEMSSSDNTQAPPNQSSSNSSSSDGKSSNGNMAAPPSNGQMPSGGQGGPPSGGDGGQG GPGGDGGKGGTGTGSKMQSGSGMFGTGTPGPLRLFQQELSDQISWLLPFAIFGIAGLL IAGARERRRLSVEQKETVFWVAWLVPIAGFFSVAEFFHHYYLIMLAPPIAALVGAGWV ALVHLYRNQTGWKAWLLPGAIIATTGFELFILRNYNDQIGVGWSIGVGVIGVLSAIAL LLFKQRQKPFSYYVSLAALLALLVMPMYWASTPLLYGGNSSLPETGPQLASMSGKGMG MSDATVNEKLIKYLEENNSGAEYLFATTDSNTAAPYIIKTKKAVMAIGGYSGSDPAIT LTQFKKLVKEGKVKYFLASGMGRGGNNDIVEWVEKNGKEVASEKWQSSSDQKTENTDS ADTSSSKASGENGKMGGPGGMNQSATLYELHADE*" gene 1354285..1356435 /gene="ykcB" /locus_tag="BSU_12880" /old_locus_tag="BSU12880" promotor_no_box 1355174..1355274 /Source="Nicolas_upshift_promotors" /id="U1041" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.608391608391608" /psig="0.000999000999001" /xcortree=1488 /SigmaFactorBS="catcaagcgatggtaaatcctcaaatggcaatatggcggcgc ctccatccaatggccaaatgccaagcggcggtcaaggaggccctccaagcggcggaga t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_no_box" upshifts 1355234 /Source="Nicolas_upshifts" /id="U1041" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.608391608391608" /psig="0.000999000999001" /xcortree=1488 /SigmaFactorBS="catcaagcgatggtaaatcctcaaatggcaatatggcggcgc ctccatccaatggccaaatgccaagcggcggtcaaggaggccctccaagcggcggaga t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" downshifts 1355322 /Source="Nicolas_upshifts" /id="D702" /incds=1 /nref=4 /ntot=10 /MaxReadThrough="0.56615" /MaxDrop="4.44711" /score="51.2936135" /energy="-17.5" /TU="NA" /idTUdmin="U1041" /TUdmin=0 /isTUend="TRUE" CDS 1356447..1357418 /gene="ykcC" /locus_tag="BSU_12890" /old_locus_tag="BSU12890" /EC_number="2.4.-.-" /function="16.2: Construct biomass (Anabolism)" /function="16.13: Shape" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative glycosyltransferase" /protein_id="NP_389172.2" /db_xref="EnsemblGenomes-Gn:BSU12890" /db_xref="EnsemblGenomes-Tr:CAB13146" /db_xref="GOA:O34319" /db_xref="InterPro:IPR001173" /db_xref="InterPro:IPR029044" /db_xref="SubtiList:BG13230" /db_xref="UniProtKB/Swiss-Prot:O34319" /translation="MSRHIQYSIVVPVYNEELVIHETYQRLKEVMDQTKENYELLFVN DGSKDRSIEILREHSLIDPRVKIIDFSRNFGHQIAITAGMDYAQGNAIVVIDADLQDP PELILEMIEKWKEGYEVVYAVRTKRKGETFFKKQTAAMFYRLLSGMTDIDIPIDTGDF RLMDRKVCDEMKRLKEKNPFVRGLVSWVGFKQTAVEYVRDERLAGETKYPLKKMLKLS MDGITTFSHKPLKLASYAGILMSGTGFLYMFIVLYLKLFTDSTITGWSSLIVIQLLFS GIVLLILGVIGEYIGRIYDEAKDRPLYIVQKSYGIENKRLYRDQHMS*" gene 1356447..1357418 /gene="ykcC" /locus_tag="BSU_12890" /old_locus_tag="BSU12890" S_feature complement(1356775..1357416) /Source="Nicolas_S_feature" /locus_tag="new_1356775_1357416_c" /HighExp="T-0.40H, T0.0H, Salt, T0.30H, T-1.10H, C30, T-1.40H, S0, H2O2, T1.0H" /AntisenseName="ykcC" /AntisenseCor="9.6017422892053297E-4" /AntisenseRegPval=0 /CDS_PredictionProba="NA" /TUshortSig="SigWXY" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S461" downshifts complement(1357461) /Source="Nicolas_upshifts" /id="D703" /incds=0 /nref=9 /ntot=114 /MaxReadThrough="4.36795" /MaxDrop="4.15844" /score="4.98888048" /energy="-19.1" /TU="U1042" /idTUdmin="U1044" /TUdmin=489 /isTUend="FALSE" S_feature complement(1357486..1357852) /Source="Nicolas_S_feature" /locus_tag="new_1357486_1357852_c" /HighExp="T1.0H, T1.30H, T0.30H, T2.0H, T0.0H, T2.30H, T-0.40H, T3.0H, Salt, T-1.10H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.99893799999999999" /TUshortSig="SigWXY" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S462" downshifts complement(1357529) /Source="Nicolas_upshifts" /id="D704" /incds=0 /nref=17 /ntot=157 /MaxReadThrough="6.61192" /MaxDrop="3.74411" /score="4.98888048" /energy="-19.1" /TU="U1042" /idTUdmin="U1044" /TUdmin=421 /isTUend="FALSE" promotor_-10 complement(1357832..1357847) /Source="Nicolas_upshift_promotors" /id="U1042" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1700 /SigmaFactorBS="agcggtctgaggctttttattagataaaagacctaattgttc taTGAAACTTTCtgacgagatatCCGTATATCATACAGAttgacatcattcacatcag a" /listShort="S462, S461" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1357852) /Source="Nicolas_upshifts" /id="U1042" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1700 /SigmaFactorBS="agcggtctgaggctttttattagataaaagacctaattgttc taTGAAACTTTCtgacgagatatCCGTATATCATACAGAttgacatcattcacatcag a" /listShort="S462, S461" /GFF_Attribute="listLong" promotor_-35 complement(1357859..1357868) /Source="Nicolas_upshift_promotors" /id="U1042" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1700 /SigmaFactorBS="agcggtctgaggctttttattagataaaagacctaattgttc taTGAAACTTTCtgacgagatatCCGTATATCATACAGAttgacatcattcacatcag a" /listShort="S462, S461" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(1357936..1359285) /gene="htrA" /locus_tag="BSU_12900" /old_locus_tag="BSU12900" /EC_number="3.4.21.107" /function="16.6: Maintain" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:10692364, 11133960, 11555295, 12823817, 24362423" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10692364, 11133960, 11555295, 12823817, 24362423; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="membrane bound serine protease Do, quality control protease and chaperone (heat-shock protein)" /protein_id="NP_389173.2" /db_xref="EnsemblGenomes-Gn:BSU12900" /db_xref="EnsemblGenomes-Tr:CAB13147" /db_xref="GOA:O34358" /db_xref="InterPro:IPR001478" /db_xref="InterPro:IPR001940" /db_xref="InterPro:IPR009003" /db_xref="InterPro:IPR036034" /db_xref="SubtiList:BG12608" /db_xref="UniProtKB/Swiss-Prot:O34358" /translation="MDNYRDENRTKGNENEVFLTKENDQSASYSARNVIHDQEKKKRG FGWFRPLLGGVIGGSLALGIYTFTPLGDHDSQDTAKQSSSQQQTQSVTATSTSSESKK SSSSSSAFKSEDSSKISDMVEDLSPAIVGITNLQAQSNSSLFGSSSSDSSEDTESGSG SGVIFKKENGKAYIITNNHVVEGASSLKVSLYDGTEVTAKLVGSDSLTDLAVLQISDD HVTKVANFGDSSDLRTGETVIAIGDPLGKDLSRTVTQGIVSGVDRTVSMSTSAGETSI NVIQTDAAINPGNSGGPLLNTDGKIVGINSMKISEDDVEGIGFAIPSNDVKPIAEELL SKGQIERPYIGVSMLDLEQVPQNYQEGTLGLFGSQLNKGVYIREVASGSPAEKAGLKA EDIIIGLKGKEIDTGSELRNILYKDAKIGDTVEVKILRNGKEMTKKIKLDQKEEKTS* " gene complement(1357936..1359285) /gene="htrA" /locus_tag="BSU_12900" /old_locus_tag="BSU12900" downshifts complement(1357950) /Source="Nicolas_upshifts" /id="D705" /incds=0 /nref=198 /ntot=244 /MaxReadThrough="2.95586" /MaxDrop="5.35972" /score="30.7234179" /energy="-19.9" /TU="NA" /idTUdmin="U1044" /TUdmin=0 /isTUend="TRUE" promotor_-35 1359325..1359332 /Source="Nicolas_upshift_promotors" /id="U1043" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.948051948051948" /psig="0.999000999001" /xcortree=2991 /SigmaFactorBS="tcatgttcactccgtttctctattttcacatgtctatttaTA TTGATAggtttatgacttgaGTTTATCATAAACAAAAACTgtgggataaaaatgaaaa g" /GFF_Attribute="listShort" /listLong="proG" /label="promotor_-35" promotor_-10 complement(1359337..1359356) /Source="Nicolas_upshift_promotors" /id="U1044" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.865134865134865" /psig="0.998001998001998" /xcortree=1763 /SigmaFactorBS="tttccgcactttttcacaatttcccataatcttttcattttT ATCCCACagtttttgttTATGATAAACTCAAGTCATAaacctatcaatataaatagac a" /listShort="htrA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1359345 /Source="Nicolas_upshifts" /id="U1043" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.948051948051948" /psig="0.999000999001" /xcortree=2991 /SigmaFactorBS="tcatgttcactccgtttctctattttcacatgtctatttaTA TTGATAggtttatgacttgaGTTTATCATAAACAAAAACTgtgggataaaaatgaaaa g" /GFF_Attribute="listShort" /listLong="proG" promotor_-10 1359347..1359366 /Source="Nicolas_upshift_promotors" /id="U1043" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.948051948051948" /psig="0.999000999001" /xcortree=2991 /SigmaFactorBS="tcatgttcactccgtttctctattttcacatgtctatttaTA TTGATAggtttatgacttgaGTTTATCATAAACAAAAACTgtgggataaaaatgaaaa g" /GFF_Attribute="listShort" /listLong="proG" /label="promotor_-10" upshifts complement(1359355) /Source="Nicolas_upshifts" /id="U1044" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.865134865134865" /psig="0.998001998001998" /xcortree=1763 /SigmaFactorBS="tttccgcactttttcacaatttcccataatcttttcattttT ATCCCACagtttttgttTATGATAAACTCAAGTCATAaacctatcaatataaatagac a" /listShort="htrA" /GFF_Attribute="listLong" S_feature complement(1359357..1359439) /Source="Nicolas_S_feature" /locus_tag="new_1359357_1359439_c" /HighExp="Etha, dia5, S8, S6, T2.0H, T3.30H, dia15, T5.0H, BC, Diami" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.682" /TUlongSig="NA" /TUlongPSig="NA" /label="S463" promotor_-35 complement(1359367..1359374) /Source="Nicolas_upshift_promotors" /id="U1044" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.865134865134865" /psig="0.998001998001998" /xcortree=1763 /SigmaFactorBS="tttccgcactttttcacaatttcccataatcttttcattttT ATCCCACagtttttgttTATGATAAACTCAAGTCATAaacctatcaatataaatagac a" /listShort="htrA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1359396..1359402 /Source="Nicolas_upshift_promotors" /id="U1045" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.390609390609391" /psig="0.994005994005994" /xcortree=2259 /SigmaFactorBS="aaaaactgtgggataaaaatgaaaagattatgggaaATTGTG AaaaagtgcggaaaaCGGTACACTTCATATTGTATatgaaaggactgagtcgatggaa c" /listShort="proG" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1359417..1359436 /Source="Nicolas_upshift_promotors" /id="U1045" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.390609390609391" /psig="0.994005994005994" /xcortree=2259 /SigmaFactorBS="aaaaactgtgggataaaaatgaaaagattatgggaaATTGTG AaaaagtgcggaaaaCGGTACACTTCATATTGTATatgaaaggactgagtcgatggaa c" /listShort="proG" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1359420 /Source="Nicolas_upshifts" /id="U1045" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.390609390609391" /psig="0.994005994005994" /xcortree=2259 /SigmaFactorBS="aaaaactgtgggataaaaatgaaaagattatgggaaATTGTG AaaaagtgcggaaaaCGGTACACTTCATATTGTATatgaaaggactgagtcgatggaa c" /listShort="proG" /GFF_Attribute="listLong" promotor_-10 complement(1359422..1359441) /Source="Nicolas_upshift_promotors" /id="U1046" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.416583416583417" /psig="0.682317682317682" /xcortree=624 /SigmaFactorBS="tcatatccgccatgctgccatatccaatcaatccaatctGTT CcatcgactcagtcctTTCATATACAATATGAAGTGtaccgttttccgcactttttca c" /listShort="S463, htrA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1359439) /Source="Nicolas_upshifts" /id="U1046" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.416583416583417" /psig="0.682317682317682" /xcortree=624 /SigmaFactorBS="tcatatccgccatgctgccatatccaatcaatccaatctGTT CcatcgactcagtcctTTCATATACAATATGAAGTGtaccgttttccgcactttttca c" /listShort="S463, htrA" /GFF_Attribute="listLong" CDS 1359454..1360272 /gene="proCC" /locus_tag="BSU_12910" /old_locus_tag="BSU12910" /EC_number="1.5.1.2" /function="16.8: Protect" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:11418582" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11418582; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="redundant pyrroline-5-carboxylate reductase" /protein_id="NP_389174.1" /db_xref="EnsemblGenomes-Gn:BSU12910" /db_xref="EnsemblGenomes-Tr:CAB13148" /db_xref="GOA:Q00777" /db_xref="InterPro:IPR000304" /db_xref="InterPro:IPR008927" /db_xref="InterPro:IPR028939" /db_xref="InterPro:IPR029036" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG10841" /db_xref="UniProtKB/Swiss-Prot:Q00777" /translation="MEQIGLIGYGSMADMIARQLLKHEQIKENELFIETRTKGERLRA LMSDYPNVSADPLENWANTCQLILICVPPLHVIETMRRLYPYVNRNTHIVSIAAGVPL RLLEAETEAGISRVIPAITSEAEAGISLVVHSEALAAEKKERLNELLSVFSRVREIKE SNLDVASNLTSSAPGFIAAIFEELALSAVRNSSLSKEEAFDFLIHSLYGTGKMLIEKN MSFEETLERVATKGGITGEGAEVIHASVPDVFDEVFERTLRKYELLTEQVGKQT*" gene 1359454..1360272 /gene="proCC" /locus_tag="BSU_12910" /old_locus_tag="BSU12910" promotor_-35 complement(1359457..1359460) /Source="Nicolas_upshift_promotors" /id="U1046" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.416583416583417" /psig="0.682317682317682" /xcortree=624 /SigmaFactorBS="tcatatccgccatgctgccatatccaatcaatccaatctGTT CcatcgactcagtcctTTCATATACAATATGAAGTGtaccgttttccgcactttttca c" /listShort="S463, htrA" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 1360250 /Source="Nicolas_upshifts" /id="D706" /incds=0 /nref=90 /ntot=220 /MaxReadThrough="1.3818" /MaxDrop="4.43155" /score="-5.08770006" /energy="-5.3" /TU="NA" /idTUdmin="U1045" /TUdmin=0 /isTUend="TRUE" promotor_-35 1360329..1360336 /Source="Nicolas_upshift_promotors" /id="U1047" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.984015984015984" /psig=1 /xcortree=2874 /SigmaFactorBS="tttatcactgaatgattgagatttttcccagttaTATTGCAT ttttcctcttttttTAATATAATTTGTTAGAATAttcataatttagtaaaaaaggagg a" /listShort="dppA, dppB, dppC, dppD, dppE, ykfA, ykfB, ykfC, ykfD, S465" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1360351..1360370 /Source="Nicolas_upshift_promotors" /id="U1047" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.984015984015984" /psig=1 /xcortree=2874 /SigmaFactorBS="tttatcactgaatgattgagatttttcccagttaTATTGCAT ttttcctcttttttTAATATAATTTGTTAGAATAttcataatttagtaaaaaaggagg a" /listShort="dppA, dppB, dppC, dppD, dppE, ykfA, ykfB, ykfC, ykfD, S465" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1360355 /Source="Nicolas_upshifts" /id="U1047" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.984015984015984" /psig=1 /xcortree=2874 /SigmaFactorBS="tttatcactgaatgattgagatttttcccagttaTATTGCAT ttttcctcttttttTAATATAATTTGTTAGAATAttcataatttagtaaaaaaggagg a" /listShort="dppA, dppB, dppC, dppD, dppE, ykfA, ykfB, ykfC, ykfD, S465" /GFF_Attribute="listLong" CDS 1360401..1361225 /gene="dppA" /locus_tag="BSU_12920" /old_locus_tag="BSU12920" /EC_number="3.4.11.-" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:11069674, 11473256, 19340926" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11069674, 11473256, 19340926; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="D-alanyl-aminopeptidase" /protein_id="NP_389175.2" /db_xref="EnsemblGenomes-Gn:BSU12920" /db_xref="EnsemblGenomes-Tr:CAB13149" /db_xref="GOA:P26902" /db_xref="InterPro:IPR007035" /db_xref="InterPro:IPR027476" /db_xref="InterPro:IPR033824" /db_xref="InterPro:IPR036177" /db_xref="PDB:1HI9" /db_xref="SubtiList:BG10842" /db_xref="UniProtKB/Swiss-Prot:P26902" /translation="MKLYMSVDMEGISGLPDDTFVDSGKRNYERGRLIMTEEANYCIA EAFNSGCTEVLVNDSHSKMNNLMVEKLHPEADLISGDVKPFSMVEGLDDTFRGALFLG YHARASTPGVMSHSMIFGVRHFYINDRPVGELGLNAYVAGYYDVPVLMVAGDDRAAKE AEELIPNVTTAAVKQTISRSAVKCLSPAKAGRLLTEKTAFALQNKDKVKPLTPPDRPV LSIEFANYGQAEWANLMPGTEIKTGTTTVQFQAKDMLEAYQAMLVMTELAMRTSFC*" gene 1360401..1361225 /gene="dppA" /locus_tag="BSU_12920" /old_locus_tag="BSU12920" CDS 1361242..1362168 /gene="dppB" /locus_tag="BSU_12930" /old_locus_tag="BSU12930" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:1766370, 7536291, 15849754, 16850406" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1766370, 7536291, 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="dipeptide ABC transporter (permease)" /protein_id="NP_389176.1" /db_xref="EnsemblGenomes-Gn:BSU12930" /db_xref="EnsemblGenomes-Tr:CAB13150" /db_xref="GOA:P26903" /db_xref="InterPro:IPR000515" /db_xref="InterPro:IPR035906" /db_xref="SubtiList:BG10843" /db_xref="UniProtKB/Swiss-Prot:P26903" /translation="MARYMIKRFWAMAATILVITTLTFVLMKVIPGSPFNEERGTNEA VQKNLEAYYHLDDPLIFQYIFYLKSIITFDFGPSIKKPSDSVNDMLERGFPVSFELGM TAIVIAVISGLVLGVIAALRRNGFLDYAAMSLAVLGISIPNFILATLLIQQFAVNLKL FPAATWTSPIHMVLPTAALAVGPMAIIARLTRSSMVEVLTQDYIRTAKAKGLSPFKII VKHALRNALMPVITVLGTLVASILTGSFVIEKIFAIPGMGKYFVESINQRDYPVIMGT TVFYSVILIIMLFLVDLAYGLLDPRIKLHKKG*" gene 1361242..1362168 /gene="dppB" /locus_tag="BSU_12930" /old_locus_tag="BSU12930" CDS 1362174..1363136 /gene="dppC" /locus_tag="BSU_12940" /old_locus_tag="BSU12940" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:1766370, 7536291, 15849754, 16850406" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1766370, 7536291, 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="dipeptide ABC transporter (permease)" /protein_id="NP_389177.1" /db_xref="EnsemblGenomes-Gn:BSU12940" /db_xref="EnsemblGenomes-Tr:CAB13151" /db_xref="GOA:P26904" /db_xref="InterPro:IPR000515" /db_xref="InterPro:IPR025966" /db_xref="InterPro:IPR035906" /db_xref="SubtiList:BG10844" /db_xref="UniProtKB/Swiss-Prot:P26904" /translation="MNLPVQTDERQPEQHNQVPDEWFVLNQEKNREADSVKRPSLSYT QDAWRRLKKNKLAMAGLFILLFLFVMAVIGPFLSPHSVVRQSLTEQNLPPSADHWFGT DELGRDVFTRTWYGARISLFVGVMAALIDFLIGVIYGGVAGYKGGRIDSIMMRIIEVL YGLPYLLVVILLMVLMGPGLGTIIVALTVTGWVGMARIVRGQVLQIKNYEYVLASKTF GAKTFRIIRKNLLPNTMGAIIVQMTLTVPAAIFAESFLSFLGLGIQAPFASWGVMAND GLPTILSGHWWRLFFPAFFISLTMYAFNVLGDGLQDALDPKLRR*" gene 1362174..1363136 /gene="dppC" /locus_tag="BSU_12940" /old_locus_tag="BSU12940" promotor_-35 1362868..1362873 /Source="Nicolas_upshift_promotors" /id="U1048" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=761 /SigmaFactorBS="cgcgaaaacctttcgcatcatccggaagaatttgctgcCGAA TActatgggagcgatcaTCGTACAAATGACATTAACcgtacctgccgccatattcgca g" /listShort="dppD, dppE, ykfA, ykfB, ykfC, ykfD, S465" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1362889..1362907 /Source="Nicolas_upshift_promotors" /id="U1048" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=761 /SigmaFactorBS="cgcgaaaacctttcgcatcatccggaagaatttgctgcCGAA TActatgggagcgatcaTCGTACAAATGACATTAACcgtacctgccgccatattcgca g" /listShort="dppD, dppE, ykfA, ykfB, ykfC, ykfD, S465" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1362890 /Source="Nicolas_upshifts" /id="U1048" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=761 /SigmaFactorBS="cgcgaaaacctttcgcatcatccggaagaatttgctgcCGAA TActatgggagcgatcaTCGTACAAATGACATTAACcgtacctgccgccatattcgca g" /listShort="dppD, dppE, ykfA, ykfB, ykfC, ykfD, S465" /GFF_Attribute="listLong" CDS 1363141..1364148 /gene="dppD" /locus_tag="BSU_12950" /old_locus_tag="BSU12950" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:7536291" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7536291; Product type t : transporter" /codon_start=1 /transl_table=11 /product="dipeptide ABC transporter (ATP-binding subunit)" /protein_id="NP_389178.1" /db_xref="EnsemblGenomes-Gn:BSU12950" /db_xref="EnsemblGenomes-Tr:CAB13152" /db_xref="GOA:P26905" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR013563" /db_xref="InterPro:IPR017871" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG10845" /db_xref="UniProtKB/Swiss-Prot:P26905" /translation="MEKVLSVQNLHVSFTTYGGTVQAVRGVSFDLYKGETFAIVGESG CGKSVTSQSIMGLLPPYSAKVTDGRILFKNKDLCRLSDKEMRGIRGADISMIFQDPMT ALNPTLTVGDQLGEALLRHKKMSKKAARKEVLSMLSLVGIPDPGERLKQYPHQFSGGM RQRIVIAMALICEPDILIADEPTTALDVTIQAQILELFKEIQRKTDVSVILITHDLGV VAQVADRVAVMYAGKMAEIGTRKDIFYQPQHPYTKGLLGSVPRLDLNGAELTPIDGTP PDLFSPPPGCPFAARCPNRMVVCDRVYPGQTIRSDSHTVNCWLQDQRAEHAVLSGDAK D*" gene 1363141..1364148 /gene="dppD" /locus_tag="BSU_12950" /old_locus_tag="BSU12950" CDS 1364151..1365800 /gene="dppE" /locus_tag="BSU_12960" /old_locus_tag="BSU12960" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:7783641, 8793880, 11390694" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7783641, 8793880, 11390694; Product type lp: lipoprotein" /codon_start=1 /transl_table=11 /product="dipeptide ABC transporter (dipeptide-binding lipoprotein)" /protein_id="NP_389179.2" /db_xref="EnsemblGenomes-Gn:BSU12960" /db_xref="EnsemblGenomes-Tr:CAB13153" /db_xref="GOA:P26906" /db_xref="InterPro:IPR000914" /db_xref="InterPro:IPR023765" /db_xref="InterPro:IPR030678" /db_xref="SubtiList:BG10846" /db_xref="UniProtKB/Swiss-Prot:P26906" /translation="MKRGKRMKRVKKLWGMGLALGLSFALMGCTANEQAGKEGSHDKA KTSGEKVLYVNNENEPTSFDPPIGFNNVSWQPLNNIMEGLTRLGKDHEPEPAMAEKWS VSKDNKTYTFTIRENAKWTNGDPVTAGDFEYAWKRMLDPKKGASSAFLGYFIEGGEAY NSGKGKKDDVKVTAKDDRTLEVTLEAPQKYFLSVVSNPAYFPVNEKVDKDNPKWFAES DTFVGNGPFKLTEWKHDDSITMEKSDTYWDKDTVKLDKVKWAMVSDRNTDYQMFQSGE LDTAYVPAELSDQLLDQDNVNIVDQAGLYFYRFNVNMEPFQNENIRKAFAMAVDQEEI VKYVTKNNEKPAHAFVSPGFTQPDGKDFREAGGDLIKPNESKAKQLLEKGMKEENYNK LPAITLTYSTKPEHKKIAEAIQQKLKNSLGVDVKLANMEWNVFLEDQKALKFQFSQSS FLPDYADPISFLEAFQTGNSMNRTGWANKEYDQLIKQAKNEADEKTRFSLMHQAEELL INEAPIIPVYFYNQVHLQNEQVKGIVRHPVGYIDLKWADKN*" gene 1364151..1365800 /gene="dppE" /locus_tag="BSU_12960" /old_locus_tag="BSU12960" downshifts 1365794 /Source="Nicolas_upshifts" /id="D707" /incds=0 /nref=2 /ntot=25 /MaxReadThrough="6.73127" /MaxDrop="3.5888" /score="22.838155" /energy="-13.9" /TU="U1047,U1048" /idTUdmin="U1048" /TUdmin="-4469" /isTUend="FALSE" CDS 1365888..1366847 /gene="ldcA" /locus_tag="BSU_12970" /old_locus_tag="BSU12970" /EC_number="3.4.17.-" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 10428950, 15101989, 18535144, 20944232, 24123814; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="muropeptide L,D-carboxypeptidase" /protein_id="NP_389180.2" /db_xref="EnsemblGenomes-Gn:BSU12970" /db_xref="EnsemblGenomes-Tr:CAB13154" /db_xref="GOA:O34851" /db_xref="InterPro:IPR003507" /db_xref="InterPro:IPR027461" /db_xref="InterPro:IPR027478" /db_xref="InterPro:IPR029062" /db_xref="SubtiList:BG13231" /db_xref="UniProtKB/Swiss-Prot:O34851" /translation="MKGVFSLNYKPKALNKGDTVGVIAPASPPDPKKLDTALLFLEEL GLQVKLGKALKNQHGYLAGQDDERLADLHEMFRDDEVKAVLCACGGFGTGRIAAGIDF SLIRKHPKIFWGYSDITFLHTAIHQNTGLVTFHGPMLSTDIGLDDVHPLTKASYKQLF QETEFTYTEELSPLTELVPGKAEGELVGGNLSLLTSTLGTPFEIDTRGKLLFIEDIDE EPYQIDRMLNQLKMGGKLTDAAGILVCDFHNCVPVKREKSLSLEQVLEDYIISAGRPA LRGFKIGHCSPSIAVPIGAKAAMNTAEKTAVIEAGVSEGALKT*" gene 1365888..1366847 /gene="ldcA" /locus_tag="BSU_12970" /old_locus_tag="BSU12970" CDS 1366844..1367944 /gene="aeeB" /locus_tag="BSU_12980" /old_locus_tag="BSU12980" /EC_number="5.1.1.20" /function="16.11: Scavenge (Catabolism)" /function="16.5: Explore" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:11747447, 11747448, 15101989" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11747447, 11747448, 15101989; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="L-Ala-D/L-Glu epimerase" /protein_id="NP_389181.1" /db_xref="EnsemblGenomes-Gn:BSU12980" /db_xref="EnsemblGenomes-Tr:CAB13155" /db_xref="GOA:O34508" /db_xref="InterPro:IPR013341" /db_xref="InterPro:IPR013342" /db_xref="InterPro:IPR029017" /db_xref="InterPro:IPR029065" /db_xref="InterPro:IPR034390" /db_xref="InterPro:IPR036849" /db_xref="PDB:1JPM" /db_xref="PDB:1TKK" /db_xref="SubtiList:BG13232" /db_xref="UniProtKB/Swiss-Prot:O34508" /translation="MKIIRIETSRIAVPLTKPFKTALRTVYTAESVIVRITYDSGAVG WGEAPPTLVITGDSMDSIESAIHHVLKPALLGKSLAGYEAILHDIQHLLTGNMSAKAA VEMALYDGWAQMCGLPLYQMLGGYRDTLETDYTVSVNSPEEMAADAENYLKQGFQTLK IKVGKDDIATDIARIQEIRKRVGSAVKLRLDANQGWRPKEAVTAIRKMEDAGLGIELV EQPVHKDDLAGLKKVTDATDTPIMADESVFTPRQAFEVLQTRSADLINIKLMKAGGIS GAEKINAMAEACGVECMVGSMIETKLGITAAAHFAASKRNITRFDFDAPLMLKTDVFN GGITYSGSTISMPGKPGLGIIGAALLKGEKEQ*" gene 1366844..1367944 /gene="aeeB" /locus_tag="BSU_12980" /old_locus_tag="BSU12980" CDS 1367941..1368831 /gene="eepC" /locus_tag="BSU_12990" /old_locus_tag="BSU12990" /EC_number="3.4.-.-" /function="16.11: Scavenge (Catabolism)" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:15101989, 20944232" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15101989, 20944232; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="gamma-D-glutamyl-L-diaminoacid endopeptidase" /protein_id="NP_389182.2" /db_xref="EnsemblGenomes-Gn:BSU12990" /db_xref="EnsemblGenomes-Tr:CAB13156" /db_xref="GOA:O35010" /db_xref="InterPro:IPR000064" /db_xref="SubtiList:BG13233" /db_xref="UniProtKB/Swiss-Prot:O35010" /translation="MMHTVISAVANIWTAPDSPRPSDQFMLQPTVMIRDWLERMTYDE RLGLCTDNVIQTQVLFGEKVLVTAEQGEWVSVIVPSQPSRKDPRGYPGWMKKYQLEKT KPIHTQHDVMISKPAAFLYRSNGEKEIELSFLTVLPLIAKENGYFKVSTVFGERFVRQ SDAVPVSQQKGTAEDIIQTGAFFLGLPYLWGGISGFGFDCSGFMYSIFKANGYSIPRD AGDQAKAGKGVPLDDMKAGDLLFFAYEEGKGAIHHVGLYVGGGKMLHSPKTGKSIEIL TLTETIYEKELCAVRRCFSE*" gene 1367941..1368831 /gene="eepC" /locus_tag="BSU_12990" /old_locus_tag="BSU12990" CDS 1368844..1369833 /gene="ykfD" /locus_tag="BSU_13000" /old_locus_tag="BSU13000" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15101989; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative cell wall oligopeptide ABC transporter (ATP binding protein)" /protein_id="NP_389183.2" /db_xref="EnsemblGenomes-Gn:BSU13000" /db_xref="EnsemblGenomes-Tr:CAB13157" /db_xref="GOA:C0SP98" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR013563" /db_xref="InterPro:IPR017871" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG13234" /db_xref="UniProtKB/Swiss-Prot:C0SP98" /translation="MRRLPLLEVSQLKMHFDAGKKRTVKAVDGVTFQIREGETFGLVG ESGCGKSTLGRVLMRLYQPTEGSVTYRGTNLHALSEKEQFAFNRKLQMIFQDPYASLN PRMTVREIILEPMEIHNLYNTHKARLLVVDELLEAVGLHPDFGSRYPHEFSGGQRQRI GIARALSLNPEFIVADEPISALDVSVQAQVVNLLKRLQKEKGLTFLFIAHDLSMVKHI SDRIGVMYLGHMMEITESGTLYREPLHPYTKALLSSIPIPDPELEDKRERILLKGELP SPVNPPSGCVFRTRCPEAMPECGESRPQLQEIEPGRFVACHLYRNAETKEKVR*" gene 1368844..1369833 /gene="ykfD" /locus_tag="BSU_13000" /old_locus_tag="BSU13000" S_feature complement(1369127..1369854) /Source="Nicolas_S_feature" /locus_tag="new_1369127_1369854_c" /HighExp="Etha, S7, Gly, M40t90, C30, H2O2, M0t90, dia15, T1.0H, S8" /AntisenseName="ykfD" /AntisenseCor="-6.3474114158352593E-2" /AntisenseRegPval="-0.5" /CDS_PredictionProba="NA" /TUshortSig="SigB" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S464" downshifts 1369823 /Source="Nicolas_upshifts" /id="D708" /incds=0 /nref=1 /ntot=91 /MaxReadThrough="5.08319" /MaxDrop="3.1399" /score="-3.10371155" /energy="-13.9" /TU="U1047,U1048" /idTUdmin="U1048" /TUdmin="-440" /isTUend="FALSE" S_feature 1369868..1371036 /Source="Nicolas_S_feature" /locus_tag="new_1369868_1371036" /HighExp="T3.30H, T4.0H, T3.0H, T5.0H, T2.30H, T2.0H, S1, M9-stat, T1.30H, HiOs" /AntisenseName="ykgB" /AntisenseCor="-0.33524952291190102" /AntisenseRegPval="-7.8" /CDS_PredictionProba="NA" /TUshortSig="SigEF, SigA" /TUshortPSig="0.997, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S465" CDS complement(1369876..1370925) /gene="pgl" /locus_tag="BSU_13010" /old_locus_tag="BSU13010" /EC_number="3.1.1.31" /function="16.2: Construct biomass (Anabolism)" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:22960854, 28032445" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 22960854, 28032445; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="6-phosphogluconolactonase" /protein_id="NP_389184.1" /db_xref="EnsemblGenomes-Gn:BSU13010" /db_xref="EnsemblGenomes-Tr:CAB13158" /db_xref="GOA:O34499" /db_xref="InterPro:IPR011048" /db_xref="InterPro:IPR015943" /db_xref="InterPro:IPR019405" /db_xref="SubtiList:BG13236" /db_xref="UniProtKB/Swiss-Prot:O34499" /translation="MTKYIGYVGTYTKGGSEGIYSFELDTEKKALSEPKLAAKLGNPT YVATNKNNTILYSIEKADGQGGVAAYQIDKNSGELTFLNHQLIDGPSPCHVSVDDQNQ FVLTANYHSGKVHVFPVQEDGSLQSPVSEAAHTGKGPHERQEKPHTHYAGFTPEHNYV VAVDLGIDKLYTYKLKDGVLTESGSHSFAPGAGPRHIAFHPKEKYAYVMTELSNEVIA LEYNPTAGEFREIQVVSAIPDDFTDNSQGSAIHVTQDGRFVYVANRGHDSIAVFEVNQ YSGELAFVERVSTEGNWPRDFVFDPTEGFLVASNEETGNLVLFERDKETGRLTLLPST VSVPYPVCVKFLHQV*" gene complement(1369876..1370925) /gene="pgl" /locus_tag="BSU_13010" /old_locus_tag="BSU13010" downshifts complement(1369899) /Source="Nicolas_upshifts" /id="D709" /incds=0 /nref=208 /ntot=262 /MaxReadThrough="5.12776" /MaxDrop="6.0668" /score="24.6986564" /energy="-15.6" /TU="U1050" /idTUdmin="U1049" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(1370952..1370971) /Source="Nicolas_upshift_promotors" /id="U1049" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.524475524475524" /psig="0.996003996003996" /xcortree=2235 /SigmaFactorBS="ggcgaatgaagaatcttcccctttttcatgTTTTGAACagct tattttatcaAGATACGTTAATATAGAGGTgacatcatttttaagggggaaatcgcat g" /listShort="ykgB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1370963) /Source="Nicolas_upshifts" /id="U1049" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.524475524475524" /psig="0.996003996003996" /xcortree=2235 /SigmaFactorBS="ggcgaatgaagaatcttcccctttttcatgTTTTGAACagct tattttatcaAGATACGTTAATATAGAGGTgacatcatttttaagggggaaatcgcat g" /listShort="ykgB" /GFF_Attribute="listLong" promotor_-35 complement(1370986..1370993) /Source="Nicolas_upshift_promotors" /id="U1049" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.524475524475524" /psig="0.996003996003996" /xcortree=2235 /SigmaFactorBS="ggcgaatgaagaatcttcccctttttcatgTTTTGAACagct tattttatcaAGATACGTTAATATAGAGGTgacatcatttttaagggggaaatcgcat g" /listShort="ykgB" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(1371015..1371875) /gene="ddaH" /locus_tag="BSU_13020" /old_locus_tag="BSU13020" /EC_number="3.5.3.18" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 27258038; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="N(G),N(G)-dimethylarginine dimethylaminohydrolase" /protein_id="NP_389185.2" /db_xref="EnsemblGenomes-Gn:BSU13020" /db_xref="EnsemblGenomes-Tr:CAB13159" /db_xref="GOA:O34497" /db_xref="InterPro:IPR033199" /db_xref="SubtiList:BG13235" /db_xref="UniProtKB/Swiss-Prot:O34497" /translation="MDVSIPKSQHKTVCRTEYGTLQKVILCKPEHMTIKDVINETQKH FEDDNIHVKTANDQHSRLVEALRSHNVEVVLLPVRDGLPEQVFTRDIGFVIGEKAFLS SMTEPIRQGEEAVIKDFFHSQGISYTRMLDTSIEGGDVIIDDDIVYVGISQRTDISAI GQLEEALPEYTIVPVKLHEKFLHLDCVFNIISESEALIYSQAIEPDAADMLAKRYDLI EVPEDEQFTLGTNVLSIGKKTIISLPGNRHVNQQLSKRGYHIIEIDLSEIIKSGGSFR CCTMPLIRGE*" gene complement(1371015..1371875) /gene="ddaH" /locus_tag="BSU_13020" /old_locus_tag="BSU13020" promotor_-10 complement(1371900..1371918) /Source="Nicolas_upshift_promotors" /id="U1050" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=242 /SigmaFactorBS="aaacaatattctcttccatttgtctaaaatttaaaatGGTTT AAtgattttcatgatgaGGGAATAATAAATGTATTCttcacactttaggaggaaaaac a" /listShort="ykgA, ykgB, S464" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1371917) /Source="Nicolas_upshifts" /id="U1050" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=242 /SigmaFactorBS="aaacaatattctcttccatttgtctaaaatttaaaatGGTTT AAtgattttcatgatgaGGGAATAATAAATGTATTCttcacactttaggaggaaaaac a" /listShort="ykgA, ykgB, S464" /GFF_Attribute="listLong" promotor_-35 complement(1371934..1371940) /Source="Nicolas_upshift_promotors" /id="U1050" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=242 /SigmaFactorBS="aaacaatattctcttccatttgtctaaaatttaaaatGGTTT AAtgattttcatgatgaGGGAATAATAAATGTATTCttcacactttaggaggaaaaac a" /listShort="ykgA, ykgB, S464" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1371949..1371956 /Source="Nicolas_upshift_promotors" /id="U1051" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.933066933066933" /psig=1 /xcortree=2004 /SigmaFactorBS="cctcatcatgaaaatcattaaaccattttaaaTTTTAGACaa atggaagagaaTATTGTTTAATAGGAGAATAtaagtgcatttagctaaaagatcagac a" /listShort="ykhA, S466, hmp" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1371970..1371989 /Source="Nicolas_upshift_promotors" /id="U1051" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.933066933066933" /psig=1 /xcortree=2004 /SigmaFactorBS="cctcatcatgaaaatcattaaaccattttaaaTTTTAGACaa atggaagagaaTATTGTTTAATAGGAGAATAtaagtgcatttagctaaaagatcagac a" /listShort="ykhA, S466, hmp" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1371977 /Source="Nicolas_upshifts" /id="U1051" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.933066933066933" /psig=1 /xcortree=2004 /SigmaFactorBS="cctcatcatgaaaatcattaaaccattttaaaTTTTAGACaa atggaagagaaTATTGTTTAATAGGAGAATAtaagtgcatttagctaaaagatcagac a" /listShort="ykhA, S466, hmp" /GFF_Attribute="listLong" CDS 1372035..1372553 /gene="ykhA" /locus_tag="BSU_13030" /old_locus_tag="BSU13030" /EC_number="3.1.2.-" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 12426338, 18247525, 24623648, 24722906; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="promiscuous acyl-CoA thioesterase" /protein_id="NP_389186.2" /db_xref="EnsemblGenomes-Gn:BSU13030" /db_xref="EnsemblGenomes-Tr:CAB13160" /db_xref="GOA:P49851" /db_xref="InterPro:IPR006683" /db_xref="InterPro:IPR029069" /db_xref="InterPro:IPR033120" /db_xref="SubtiList:BG11417" /db_xref="UniProtKB/Swiss-Prot:P49851" /translation="METPETRFCKESKVVKTSRVFPLDTNNHNTLFGGKLMSYIDDIA SISAARHCRRETVTASMDSVDFLKPIGQKDSVCLESYVTWVGTSSMEVFVKVIKEHLM TGERELAATSFLTFVALDSNGKPVPVPRVVPETEEEIMLHNTAVQRANERKNRKRHSQ ALANALGTDKPW*" gene 1372035..1372553 /gene="ykhA" /locus_tag="BSU_13030" /old_locus_tag="BSU13030" downshifts 1372544 /Source="Nicolas_upshifts" /id="D710" /incds=0 /nref=34 /ntot=265 /MaxReadThrough="4.66856" /MaxDrop="4.77681" /score="24.0889455" /energy="-10.9" /TU="U1051" /idTUdmin="U1051" /TUdmin="-1436" /isTUend="FALSE" promotor_-35 1372618..1372624 /Source="Nicolas_upshift_promotors" /id="U1052" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=854 /SigmaFactorBS="tgttttgggtttttttgtacttttcaatggtgattattacaa TGGTTAGtccgtttttgctaGGGGATTCTATAaaaaagcaacaaatgtcatgttaaat t" /listShort="S466, hmp" /listLong="S467, ykjA, ykkA" /label="promotor_-35" S_feature 1372636..1372742 /Source="Nicolas_S_feature" /locus_tag="new_1372636_1372742" /HighExp="Etha, S5, S6, S8, nit, S7, ferm, S4, dia15, dia5" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigGF, SigA" /TUshortPSig="0.998, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S466" upshifts 1372636 /Source="Nicolas_upshifts" /id="U1052" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=854 /SigmaFactorBS="tgttttgggtttttttgtacttttcaatggtgattattacaa TGGTTAGtccgtttttgctaGGGGATTCTATAaaaaagcaacaaatgtcatgttaaat t" /listShort="S466, hmp" /listLong="S467, ykjA, ykkA" promotor_-10 1372638..1372649 /Source="Nicolas_upshift_promotors" /id="U1052" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=854 /SigmaFactorBS="tgttttgggtttttttgtacttttcaatggtgattattacaa TGGTTAGtccgtttttgctaGGGGATTCTATAaaaaagcaacaaatgtcatgttaaat t" /listShort="S466, hmp" /listLong="S467, ykjA, ykkA" /label="promotor_-10" promotor_-35 1372717..1372720 /Source="Nicolas_upshift_promotors" /id="U1053" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.452547452547453" /psig="0.99000999000999" /xcortree=1618 /SigmaFactorBS="ttgtgacaactttattaaagattcattttagatATATctttt attcgtaagaTCATGTATTTTAAAGATATAttttaaatacatcttttcgaaaggattg t" /listShort="hmp, S467, ykjA, ykkA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1372736..1372755 /Source="Nicolas_upshift_promotors" /id="U1053" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.452547452547453" /psig="0.99000999000999" /xcortree=1618 /SigmaFactorBS="ttgtgacaactttattaaagattcattttagatATATctttt attcgtaagaTCATGTATTTTAAAGATATAttttaaatacatcttttcgaaaggattg t" /listShort="hmp, S467, ykjA, ykkA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1372744 /Source="Nicolas_upshifts" /id="U1053" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.452547452547453" /psig="0.99000999000999" /xcortree=1618 /SigmaFactorBS="ttgtgacaactttattaaagattcattttagatATATctttt attcgtaagaTCATGTATTTTAAAGATATAttttaaatacatcttttcgaaaggattg t" /listShort="hmp, S467, ykjA, ykkA" /GFF_Attribute="listLong" CDS 1372792..1373991 /gene="hmpA" /locus_tag="BSU_13040" /old_locus_tag="BSU13040" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:10658656, 10972836, 12469342, 15231799, 15751990, 16261196, 16517672, 17293416, 24214949, 26786044" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10658656, 10972836, 12469342, 15231799, 15751990, 16261196, 16517672, 17293416, 24214949, 26786044; Product type c: carrier" /codon_start=1 /transl_table=11 /product="flavohemoglobin" /protein_id="NP_389187.1" /db_xref="EnsemblGenomes-Gn:BSU13040" /db_xref="EnsemblGenomes-Tr:CAB13161" /db_xref="GOA:P49852" /db_xref="InterPro:IPR000971" /db_xref="InterPro:IPR001221" /db_xref="InterPro:IPR001433" /db_xref="InterPro:IPR008333" /db_xref="InterPro:IPR009050" /db_xref="InterPro:IPR017927" /db_xref="InterPro:IPR017938" /db_xref="InterPro:IPR023950" /db_xref="SubtiList:BG11418" /db_xref="UniProtKB/Swiss-Prot:P49852" /translation="MLDNKTIEIIKSTVPVLQQHGETITGRFYDRMFQDHPELLNIFN QTNQKKKTQRTALANAVIAAAANIDQLGNIIPVVKQIGHKHRSIGIKPEHYPIVGKYL LIAIKDVLGDAATPDIMQAWEKAYGVIADAFIGIEKDMYEQAEEQAGGWKEYKPFVIA KKERESKEITSFYLKPEDSKPLPEFQAGQYISIKVRIPDSEYTHIRQYSLSDMPGKDY YRISVKKDGVVSSYLHDGLQEGDSIEISAPAGDFVLDHASQKDLVLISAGVGITPMIS MLKTSVSKQPERQILFIHAAKNSEYHALRHEVEEAAKHSAVKTAFVYREPTEEDRAGD LHFHEGQIDQQFLKELIANTDADYYICGSPSFITAMHKLVSELGSAPESIHYELFGPQ LSLAQSV*" gene 1372792..1373991 /gene="hmpA" /locus_tag="BSU_13040" /old_locus_tag="BSU13040" downshifts 1373980 /Source="Nicolas_upshifts" /id="D711" /incds=0 /nref=10 /ntot=59 /MaxReadThrough="6.06442" /MaxDrop="4.19301" /score="11.2868967" /energy="-9.3" /TU="U1053" /idTUdmin="U1051" /TUdmin=0 /isTUend="TRUE" S_feature 1374025..1374396 /Source="Nicolas_S_feature" /locus_tag="new_1374025_1374396" /HighExp="nit, B36, B60, Etha, BI, M40t90, LBGtran, M0t90, BT, S6" /AntisenseName="ykzH" /AntisenseCor="7.6554747052539299E-2" /AntisenseRegPval="-0.7" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.99" /TUlongSig="SigGF" /TUlongPSig="0.998" /label="S467" CDS complement(1374068..1374292) /gene="ykzH" /locus_tag="BSU_13050" /old_locus_tag="BSU13050" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_389188.1" /db_xref="EnsemblGenomes-Gn:BSU13050" /db_xref="EnsemblGenomes-Tr:CAB13162" /db_xref="SubtiList:BG13336" /db_xref="UniProtKB/Swiss-Prot:O31653" /translation="MKNQKSNTLWPFDLPLAPQPEGYQQQTIDRLAGLELRMKQLIRA IEVNNELLRTMQEQQNRVCTNGSGSVIVRM*" gene complement(1374068..1374292) /gene="ykzH" /locus_tag="BSU_13050" /old_locus_tag="BSU13050" promotor_-35 1374372..1374378 /Source="Nicolas_upshift_promotors" /id="U1054" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=927 /SigmaFactorBS="gttcaggcgatatgcacgttcgcctagacactgaTGCATAGa gggcctgccacgGGGCACAATAGGctcaatatgaccagcggatggaggtaaagatcgg t" /listShort="ykjA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1374392..1374403 /Source="Nicolas_upshift_promotors" /id="U1054" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=927 /SigmaFactorBS="gttcaggcgatatgcacgttcgcctagacactgaTGCATAGa gggcctgccacgGGGCACAATAGGctcaatatgaccagcggatggaggtaaagatcgg t" /listShort="ykjA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1374398 /Source="Nicolas_upshifts" /id="U1054" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=927 /SigmaFactorBS="gttcaggcgatatgcacgttcgcctagacactgaTGCATAGa gggcctgccacgGGGCACAATAGGctcaatatgaccagcggatggaggtaaagatcgg t" /listShort="ykjA" /GFF_Attribute="listLong" CDS 1374437..1375168 /gene="ykjA" /locus_tag="BSU_13060" /old_locus_tag="BSU13060" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved membrane protein of unknown function" /protein_id="NP_389189.1" /db_xref="EnsemblGenomes-Gn:BSU13060" /db_xref="EnsemblGenomes-Tr:CAB13163" /db_xref="GOA:P49853" /db_xref="InterPro:IPR007353" /db_xref="InterPro:IPR023090" /db_xref="SubtiList:BG11419" /db_xref="UniProtKB/Swiss-Prot:P49853" /translation="MLWMVWVFLLKPVIVFSIAYILFRLAGKKAVSQMNNFDLLLTFA IGTIISEPILTSKLPMSIYYAGAFLVLYLIMSKLSLSNKWRWLLVVSPTVLIRNGDID ERGLRKERLTVNELLGKLREKGYADPADIDLAIIEETGEVSVIPKEEARAVQVRDLNM EAERNFIPIPLILDGEILDHNLKYLQKNRSWLFEKLEEKGYSPKLLSSIILGTMNARG DISLDLNTANEPQHDPYLYKPGNNN*" gene 1374437..1375168 /gene="ykjA" /locus_tag="BSU_13060" /old_locus_tag="BSU13060" downshifts 1375146 /Source="Nicolas_upshifts" /id="D712" /incds=0 /nref=14 /ntot=29 /MaxReadThrough="2.84532" /MaxDrop="4.44655" /score="17.2468985" /energy="-7.2" /TU="U1053" /idTUdmin="U1054" /TUdmin=0 /isTUend="TRUE" promotor_-35 1375207..1375215 /Source="Nicolas_upshift_promotors" /id="U1055" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=551 /SigmaFactorBS="ctctctcttgtaatgagagcttttttcttttttAAAGGGAAT ttttgtttggTGTCAAATGTACCTAGTTAggaggggaactgaacatgaaggacttatc c" /listShort="ykkA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1375226..1375244 /Source="Nicolas_upshift_promotors" /id="U1055" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=551 /SigmaFactorBS="ctctctcttgtaatgagagcttttttcttttttAAAGGGAAT ttttgtttggTGTCAAATGTACCTAGTTAggaggggaactgaacatgaaggacttatc c" /listShort="ykkA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1375234 /Source="Nicolas_upshifts" /id="U1055" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=551 /SigmaFactorBS="ctctctcttgtaatgagagcttttttcttttttAAAGGGAAT ttttgtttggTGTCAAATGTACCTAGTTAggaggggaactgaacatgaaggacttatc c" /listShort="ykkA" /GFF_Attribute="listLong" CDS 1375260..1375787 /gene="ykkA" /locus_tag="BSU_13070" /old_locus_tag="BSU13070" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_389190.1" /db_xref="EnsemblGenomes-Gn:BSU13070" /db_xref="EnsemblGenomes-Tr:CAB13164" /db_xref="InterPro:IPR024775" /db_xref="InterPro:IPR034660" /db_xref="SubtiList:BG11420" /db_xref="UniProtKB/Swiss-Prot:P49854" /translation="MKDLSIRNDMAPTVSLLYSAVEENSLRLASIVSHMTHSELYYKG RCQTKNSTAQLLHHITNVDIRWVWRIKENRIPDHIEQAYGPMTDESGRLPEPVNQPDL DELLKRHQHVVEKLKSVCFTLTENALNQPLSFEGDTATIRWGIWHMADHNRYHQAHIE ALKKEWKQDVAKYER*" gene 1375260..1375787 /gene="ykkA" /locus_tag="BSU_13070" /old_locus_tag="BSU13070" CDS 1375777..1376295 /gene="ykkB" /locus_tag="BSU_13080" /old_locus_tag="BSU13080" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 12793527; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative N-acetyltransferase" /protein_id="NP_389191.1" /db_xref="EnsemblGenomes-Gn:BSU13080" /db_xref="EnsemblGenomes-Tr:CAB13165" /db_xref="GOA:P49855" /db_xref="InterPro:IPR000182" /db_xref="InterPro:IPR016181" /db_xref="SubtiList:BG11421" /db_xref="UniProtKB/Swiss-Prot:P49855" /translation="MNAKTKLVTDRIRLRCMEDRDQATLFGLLFNDPDVMTYYSGLKD KRQTREWVNWNQRNEKGYGVSLWIAEDKRTGEFLGQCGIVPQQIENQTVMEIGYMFAR RHWGNGYAQEAARACLDYGFNERQFGKMAALIDPGNKASIRVAEKIGMHYSKTIRKWN KPIAVYERKSYN*" gene 1375777..1376295 /gene="ykkB" /locus_tag="BSU_13080" /old_locus_tag="BSU13080" promotor_-35 1376289..1376296 /Source="Nicolas_upshift_promotors" /id="U1056" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.838161838161838" /psig=1 /xcortree=3144 /SigmaFactorBS="gaataaaccgatcgcggtatatgaaagaaaatcttaCAATTG AAagatagagctgagTTTAGTATCATGATATCATGtaaagttttctagggttccgcat g" /listShort="NA, ykkC, ykkD" /listLong="purU" /label="promotor_-35" promotor_-10 1376310..1376329 /Source="Nicolas_upshift_promotors" /id="U1056" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.838161838161838" /psig=1 /xcortree=3144 /SigmaFactorBS="gaataaaccgatcgcggtatatgaaagaaaatcttaCAATTG AAagatagagctgagTTTAGTATCATGATATCATGtaaagttttctagggttccgcat g" /listShort="NA, ykkC, ykkD" /listLong="purU" /label="promotor_-10" upshifts 1376313 /Source="Nicolas_upshifts" /id="U1056" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.838161838161838" /psig=1 /xcortree=3144 /SigmaFactorBS="gaataaaccgatcgcggtatatgaaagaaaatcttaCAATTG AAagatagagctgagTTTAGTATCATGATATCATGtaaagttttctagggttccgcat g" /listShort="NA, ykkC, ykkD" /listLong="purU" misc_RNA 1376328..1376439 /gene="gdwA" /locus_tag="BSU_misc_RNA_16" /product="guanidine-sensing riboswitch (binds free guanidinium)" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 17908319, 21317561, 27989440, 28001368, 28017522, 28107646, 28212758; Product type n: RNA" gene 1376328..1376439 /gene="gdwA" /locus_tag="BSU_misc_RNA_16" downshifts 1376402 /Source="Nicolas_upshifts" /id="D713" /incds=0 /nref=205 /ntot=246 /MaxReadThrough="3.70824" /MaxDrop="6.58389" /score="30.3456563" /energy="-18.5" /TU="U1056" /idTUdmin="U1056" /TUdmin="-789" /isTUend="FALSE" CDS 1376517..1376855 /gene="gdnC" /locus_tag="BSU_13090" /old_locus_tag="BSU13090" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:10735877, 10931887, 15096624, 28001372" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10735877, 10931887, 15096624, 28001372; Product type t: transporter" /codon_start=1 /transl_table=11 /product="guanidinium efflux transporter subunit" /protein_id="NP_389192.1" /db_xref="EnsemblGenomes-Gn:BSU13090" /db_xref="EnsemblGenomes-Tr:CAB13166" /db_xref="GOA:P49856" /db_xref="InterPro:IPR000390" /db_xref="SubtiList:BG11422" /db_xref="UniProtKB/Swiss-Prot:P49856" /translation="MKWGLVVLAAVFEVVWVIGLKHADSALTWSGTAIGIIFSFYLLM KATHSLPVGTVYAVFTGLGTAGTVLSEIVLFHEPVGWPKLLLIGVLLIGVIGLKLVTQ DETEEKGGEA*" gene 1376517..1376855 /gene="gdnC" /locus_tag="BSU_13090" /old_locus_tag="BSU13090" CDS 1376855..1377172 /gene="gdnD" /locus_tag="BSU_13100" /old_locus_tag="BSU13100" /function="16.8: Protect" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:10735877, 10931887, 15096624, 28001372" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10735877, 10931887, 15096624, 28001372; Product type t: transporter" /codon_start=1 /transl_table=11 /product="guanidinium efflux transporter subunit" /protein_id="NP_389193.1" /db_xref="EnsemblGenomes-Gn:BSU13100" /db_xref="EnsemblGenomes-Tr:CAB13167" /db_xref="GOA:P49857" /db_xref="InterPro:IPR000390" /db_xref="SubtiList:BG11423" /db_xref="UniProtKB/Swiss-Prot:P49857" /translation="MLHWISLLCAGCLEMAGVALMNQYAKEKSVKWVLLIIVGFAASF SLLSYAMETTPMGTAYAVWTGIGTAGGALIGILFYKEQKDAKRIFFIALILCSAVGLK ILS*" gene 1376855..1377172 /gene="gdnD" /locus_tag="BSU_13100" /old_locus_tag="BSU13100" promotor_-35 1377172..1377175 /Source="Nicolas_upshift_promotors" /id="U1057" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.647352647352647" /psig="0.998001998001998" /xcortree=2582 /SigmaFactorBS="tcagcagttggtttaaaaattctgtcataAATTgatttttat caaatcTTCAGTATAATGGATAAATAgtttagacttacaaagataagagggattattc a" /listShort="purU, NA, proB, proA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1377191..1377210 /Source="Nicolas_upshift_promotors" /id="U1057" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.647352647352647" /psig="0.998001998001998" /xcortree=2582 /SigmaFactorBS="tcagcagttggtttaaaaattctgtcataAATTgatttttat caaatcTTCAGTATAATGGATAAATAgtttagacttacaaagataagagggattattc a" /listShort="purU, NA, proB, proA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1377203 /Source="Nicolas_upshifts" /id="U1057" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.647352647352647" /psig="0.998001998001998" /xcortree=2582 /SigmaFactorBS="tcagcagttggtttaaaaattctgtcataAATTgatttttat caaatcTTCAGTATAATGGATAAATAgtttagacttacaaagataagagggattattc a" /listShort="purU, NA, proB, proA" /GFF_Attribute="listLong" CDS 1377243..1378145 /gene="purU" /locus_tag="BSU_13110" /old_locus_tag="BSU13110" /EC_number="3.5.1.10" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 8226647, 24108189; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="formyltetrahydrofolate hydrolase" /protein_id="NP_389194.2" /db_xref="EnsemblGenomes-Gn:BSU13110" /db_xref="EnsemblGenomes-Tr:CAB13168" /db_xref="GOA:O34990" /db_xref="InterPro:IPR002376" /db_xref="InterPro:IPR002912" /db_xref="InterPro:IPR004810" /db_xref="InterPro:IPR036477" /db_xref="SubtiList:BG13237" /db_xref="UniProtKB/Swiss-Prot:O34990" /translation="MKSYMTQRLDEYRDGNEDKGRLLVSCPDQPGIVSAVSAFLFEHG ANIIESNQYTTDPEGGRFFLRIEFDCAGIREKKSSLQAAFASVAEKFDMTWSLTLASE LKRVAIFVSKELHCLHELIWEWQTGNLMAEIAVVISNHEEARELVERLNIPFHYMKAN KDIRAEVEKKQLELLEQYDVDVIVLARYMQILTPDFVSAHPNRIINIHHSFLPAFIGA NPYKRAYERGVKLIGATSHYVTNDLDEGPIIEQDIERVDHRDNAEALKNIGRTIERSV LARAVKWHLEDRVIVHENKTIVFN*" gene 1377243..1378145 /gene="purU" /locus_tag="BSU_13110" /old_locus_tag="BSU13110" downshifts 1378136 /Source="Nicolas_upshifts" /id="D714" /incds=0 /nref=91 /ntot=226 /MaxReadThrough="3.55628" /MaxDrop="5.02155" /score="16.8011006" /energy="-13.1" /TU="U1057" /idTUdmin="U1056" /TUdmin=945 /isTUend="FALSE" promotor_-35 1378192..1378198 /Source="Nicolas_upshift_promotors" /id="U1058" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.482517482517482" /psig="0.998001998001998" /xcortree=3136 /SigmaFactorBS="agactgcaagaggcccgcgcaatgcgggctatttttgatgac aaaaaaCCTTGACaagtgtcttttttCTTTGCATAATATAAAAAAAtcattgagcgtt g" /listShort="NA, proB, proA" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 1378204 /Source="Nicolas_upshifts" /id="U1058" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.482517482517482" /psig="0.998001998001998" /xcortree=3136 /SigmaFactorBS="agactgcaagaggcccgcgcaatgcgggctatttttgatgac aaaaaaCCTTGACaagtgtcttttttCTTTGCATAATATAAAAAAAtcattgagcgtt g" /listShort="NA, proB, proA" /GFF_Attribute="listLong" promotor_-10 1378212..1378231 /Source="Nicolas_upshift_promotors" /id="U1058" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.482517482517482" /psig="0.998001998001998" /xcortree=3136 /SigmaFactorBS="agactgcaagaggcccgcgcaatgcgggctatttttgatgac aaaaaaCCTTGACaagtgtcttttttCTTTGCATAATATAAAAAAAtcattgagcgtt g" /listShort="NA, proB, proA" /GFF_Attribute="listLong" /label="promotor_-10" misc_RNA 1378233..1378443 /gene="pswB" /locus_tag="BSU_misc_RNA_17" /product="T-box riboswitch specific of proline tRNA" /experiment="publication(s) with functional evidences, PMID:11917026, 12749771, 19932103, 21233158" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11917026, 12749771, 19932103, 21233158; Product type n: RNA" /function="16.3: Control" gene 1378233..1378443 /gene="pswB" /locus_tag="BSU_misc_RNA_17" downshifts 1378401 /Source="Nicolas_upshifts" /id="D715" /incds=0 /nref=4 /ntot=52 /MaxReadThrough="6.91996" /MaxDrop="3.8361" /score="29.5878921" /energy="-17.6" /TU="U1057,U1058" /idTUdmin="U1056" /TUdmin=1210 /isTUend="FALSE" CDS 1378496..1379593 /gene="proB" /locus_tag="BSU_13120" /old_locus_tag="BSU13120" /EC_number="2.7.2.11" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:16958849, 8083159, 21233158, 21784929" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16958849, 8083159, 21233158, 21784929; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="glutamate 5-kinase" /protein_id="NP_389195.2" /db_xref="EnsemblGenomes-Gn:BSU13120" /db_xref="EnsemblGenomes-Tr:CAB13169" /db_xref="GOA:P39820" /db_xref="InterPro:IPR001048" /db_xref="InterPro:IPR001057" /db_xref="InterPro:IPR002478" /db_xref="InterPro:IPR005715" /db_xref="InterPro:IPR011529" /db_xref="InterPro:IPR015947" /db_xref="InterPro:IPR019797" /db_xref="InterPro:IPR036393" /db_xref="InterPro:IPR036974" /db_xref="SubtiList:BG10963" /db_xref="UniProtKB/Swiss-Prot:P39820" /translation="MKKQRIVVKIGSSSLTNSKGSIDEAKIREHVQAISVLKKAGHEM ILITSGAVAAGFSSLGYPSRPVTIKGKQAAAAVGQTLLMQQYMNQFKQYSLTPGQILL TRNDFSKRERYRNAYATIMELLERGVIPIINENDSTSVEELTFGDNDMLSALVSGLIH ADQLMILTDINGLYDANPNENPEAKRFDYLPEITPELLGYAGSAGSKVGTGGMKSKLL ATQTALSLGVKVFIGTGSGEQKLADILDGRGDGTYIGDKELSSVNNTRQWIQFHSPIS GEIIIDAGAEEAMIHNGSSLLPAGVVGVNGSFPKGAVVEVRGPGGVIGKGQTHYSSEE IMEAKGKRSDELDFEKTFEVIHRNDWVNVKD*" gene 1378496..1379593 /gene="proB" /locus_tag="BSU_13120" /old_locus_tag="BSU13120" promotor_-35 1378683..1378685 /Source="Nicolas_upshift_promotors" /id="U1059" /multdbtbs="-" /comp="M20" /sig="Sig-" /pcomp="0.365634365634366" /psig="0.206793206793207" /xcortree=1776 /SigmaFactorBS="gattctgattacctcgggtgccgtagcggcggggttttccag cctcggttatccatCCCgTCCCGttaccatcaaaggaaaacaggcggcggccgcggtc g" /listShort="proA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1378687..1378691 /Source="Nicolas_upshift_promotors" /id="U1059" /multdbtbs="-" /comp="M20" /sig="Sig-" /pcomp="0.365634365634366" /psig="0.206793206793207" /xcortree=1776 /SigmaFactorBS="gattctgattacctcgggtgccgtagcggcggggttttccag cctcggttatccatCCCgTCCCGttaccatcaaaggaaaacaggcggcggccgcggtc g" /listShort="proA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1378687 /Source="Nicolas_upshifts" /id="U1059" /multdbtbs="-" /comp="M20" /sig="Sig-" /pcomp="0.365634365634366" /psig="0.206793206793207" /xcortree=1776 /SigmaFactorBS="gattctgattacctcgggtgccgtagcggcggggttttccag cctcggttatccatCCCgTCCCGttaccatcaaaggaaaacaggcggcggccgcggtc g" /listShort="proA" /GFF_Attribute="listLong" CDS 1379605..1380852 /gene="proA" /locus_tag="BSU_13130" /old_locus_tag="BSU13130" /EC_number="1.2.1.41" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:16958849, 8083159, 21784929, 22720735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16958849, 8083159, 21784929, 22720735; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="gamma-glutamyl phosphate reductase" /protein_id="NP_389196.2" /db_xref="EnsemblGenomes-Gn:BSU13130" /db_xref="EnsemblGenomes-Tr:CAB13170" /db_xref="GOA:P39821" /db_xref="InterPro:IPR000965" /db_xref="InterPro:IPR012134" /db_xref="InterPro:IPR015590" /db_xref="InterPro:IPR016161" /db_xref="InterPro:IPR016162" /db_xref="InterPro:IPR020593" /db_xref="SubtiList:BG10964" /db_xref="UniProtKB/Swiss-Prot:P39821" /translation="MSEVSVKAKLAKEAAAEMIMKTTAEKDEALSLIANGLRKELDFL LAENAKDIVNGKENGLTPDIIDRLSLDEKRIRDIADAVELLIDLADPIGDSLETIEKE NGLFIEKIRVPLGVVGMIYEARPNVTVDAATLCLKTGNAVVLRGSSSAIHSNKALVSV IYRALEQSALPIHAVQLIEDTSRETAKELFTLNDGLDVLIPRGGKKLIDLVVRESTVP VLETGAGNCHIFIDETAKPQMAEKVVVNAKTQRPSVCNAIESLLIHKAWARQHGKELL DQLENAGVEIRGDELVCELHPSSKQASKEDWETEFLAPVLSVKTVENVQEAVKHIQQY GTNHSEAILTENDKNAVYFQTAVDAAAVYHNASTRFTDGFEFGYGAEIGISTQKLHAR GPMGLPALTSTKYIIKGTGQIRE*" gene 1379605..1380852 /gene="proA" /locus_tag="BSU_13130" /old_locus_tag="BSU13130" downshifts 1380843 /Source="Nicolas_upshifts" /id="D716" /incds=0 /nref=120 /ntot=228 /MaxReadThrough="4.1607" /MaxDrop="6.017" /score="11.118012" /energy="-11" /TU="U1058" /idTUdmin="U1059" /TUdmin=0 /isTUend="TRUE" promotor_-35 1380914..1380921 /Source="Nicolas_upshift_promotors" /id="U1060" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.947052947052947" /psig=1 /xcortree=3016 /SigmaFactorBS="ttacgagataagcttttttatacgcgaaaAATTGACAtttca aatttaattGTGTACAATTTAATTGTATAaaatatattgggggaatgaaaaatgagtc a" /listShort="ohrA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1380936..1380955 /Source="Nicolas_upshift_promotors" /id="U1060" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.947052947052947" /psig=1 /xcortree=3016 /SigmaFactorBS="ttacgagataagcttttttatacgcgaaaAATTGACAtttca aatttaattGTGTACAATTTAATTGTATAaaatatattgggggaatgaaaaatgagtc a" /listShort="ohrA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1380945 /Source="Nicolas_upshifts" /id="U1060" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.947052947052947" /psig=1 /xcortree=3016 /SigmaFactorBS="ttacgagataagcttttttatacgcgaaaAATTGACAtttca aatttaattGTGTACAATTTAATTGTATAaaatatattgggggaatgaaaaatgagtc a" /listShort="ohrA" /GFF_Attribute="listLong" CDS 1380978..1381403 /gene="ohrA" /locus_tag="BSU_13140" /old_locus_tag="BSU13140" /EC_number="1.11.1.15" /function="16.6: Maintain" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:11418552, 17502599, 21749987, 24184231" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11418552, 17502599, 21749987, 24184231; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="peroxiredoxin" /protein_id="NP_389197.1" /db_xref="EnsemblGenomes-Gn:BSU13140" /db_xref="EnsemblGenomes-Tr:CAB13171" /db_xref="GOA:O34762" /db_xref="InterPro:IPR003718" /db_xref="InterPro:IPR015946" /db_xref="InterPro:IPR019953" /db_xref="InterPro:IPR036102" /db_xref="SubtiList:BG13238" /db_xref="UniProtKB/Swiss-Prot:O34762" /translation="MSQPLFTATVSAVGGREGKVISSDRVLELDVAMPGTPRAKKLEK ATNPEQLFAAGYAACFDSALQLVARTERVKVETEVTANVSLLKDEADQGYKLGVTLQV KGEGVSASELEALVKKAHGVCPYSKATSGNIDVTLEVAE*" gene 1380978..1381403 /gene="ohrA" /locus_tag="BSU_13140" /old_locus_tag="BSU13140" downshifts 1381392 /Source="Nicolas_upshifts" /id="D717" /incds=0 /nref=57 /ntot=174 /MaxReadThrough="0.0429100000000009" /MaxDrop="3.90314" /score="30.9245751" /energy="-16.6" /TU="NA" /idTUdmin="U1060" /TUdmin="-1" /isTUend="TRUE" CDS complement(1381434..1381877) /gene="ohrR" /locus_tag="BSU_13150" /old_locus_tag="BSU13150" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:11983871, 17502599, 18363800, 20094649, 21749987, 24184231" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11983871, 17502599, 18363800, 20094649, 21749987, 24184231; Product type r : regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator sensing organic peroxides" /protein_id="NP_389198.1" /db_xref="EnsemblGenomes-Gn:BSU13150" /db_xref="EnsemblGenomes-Tr:CAB13172" /db_xref="GOA:O34777" /db_xref="InterPro:IPR000835" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="PDB:1Z91" /db_xref="PDB:1Z9C" /db_xref="SubtiList:BG13239" /db_xref="UniProtKB/Swiss-Prot:O34777" /translation="MENKFDHMKLENQLCFLLYASSREMTKQYKPLLDKLNITYPQYL ALLLLWEHETLTVKKMGEQLYLDSGTLTPMLKRMEQQGLITRKRSEEDERSVLISLTE DGALLKEKAVDIPGTILGLSKQSGEDLKQLKSALYTLLETLHQKN*" gene complement(1381434..1381877) /gene="ohrR" /locus_tag="BSU_13150" /old_locus_tag="BSU13150" downshifts complement(1381468) /Source="Nicolas_upshifts" /id="D718" /incds=0 /nref=105 /ntot=232 /MaxReadThrough="-0.17111" /MaxDrop="4.73026" /score="34.7008532" /energy="-16.6" /TU="NA" /idTUdmin="U1061" /TUdmin=1 /isTUend="TRUE" promotor_-10 complement(1381904..1381923) /Source="Nicolas_upshift_promotors" /id="U1061" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.672327672327672" /psig=1 /xcortree=2020 /SigmaFactorBS="tctttttaaacatgctatgtttgccgagaATAGgaaaagtga ggtttTTCAGATACAATAGAATCGAatgacaaaaaagagttggtgaacaaaatggaaa a" /listShort="ohrR" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1381910) /Source="Nicolas_upshifts" /id="U1061" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.672327672327672" /psig=1 /xcortree=2020 /SigmaFactorBS="tctttttaaacatgctatgtttgccgagaATAGgaaaagtga ggtttTTCAGATACAATAGAATCGAatgacaaaaaagagttggtgaacaaaatggaaa a" /listShort="ohrR" /GFF_Attribute="listLong" promotor_-35 complement(1381938..1381941) /Source="Nicolas_upshift_promotors" /id="U1061" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.672327672327672" /psig=1 /xcortree=2020 /SigmaFactorBS="tctttttaaacatgctatgtttgccgagaATAGgaaaagtga ggtttTTCAGATACAATAGAATCGAatgacaaaaaagagttggtgaacaaaatggaaa a" /listShort="ohrR" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1381959..1381965 /Source="Nicolas_upshift_promotors" /id="U1062" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=232 /SigmaFactorBS="aacctcacttttcctattctcggcaaacatagcaTGTTTAAa aagatcagaaagGGAAATATAACAACTAGATacaaataaggaggttgggaaatatggc a" /listShort="ohrB, ykzN, S468" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1381979..1381997 /Source="Nicolas_upshift_promotors" /id="U1062" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=232 /SigmaFactorBS="aacctcacttttcctattctcggcaaacatagcaTGTTTAAa aagatcagaaagGGAAATATAACAACTAGATacaaataaggaggttgggaaatatggc a" /listShort="ohrB, ykzN, S468" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1381985 /Source="Nicolas_upshifts" /id="U1062" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=232 /SigmaFactorBS="aacctcacttttcctattctcggcaaacatagcaTGTTTAAa aagatcagaaagGGAAATATAACAACTAGATacaaataaggaggttgggaaatatggc a" /listShort="ohrB, ykzN, S468" /GFF_Attribute="listLong" CDS 1382020..1382430 /gene="ohrB" /locus_tag="BSU_13160" /old_locus_tag="BSU13160" /EC_number="1.11.1.15" /function="16.6: Maintain" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:9696771, 11418552, 18084074" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9696771, 11418552, 18084074; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="organic hydroperoxide resistance reductase B" /protein_id="NP_389199.1" /db_xref="EnsemblGenomes-Gn:BSU13160" /db_xref="EnsemblGenomes-Tr:CAB13173" /db_xref="GOA:P80242" /db_xref="InterPro:IPR003718" /db_xref="InterPro:IPR015946" /db_xref="InterPro:IPR019953" /db_xref="InterPro:IPR036102" /db_xref="PDB:2BJO" /db_xref="SubtiList:BG19021" /db_xref="UniProtKB/Swiss-Prot:P80242" /translation="MALFTAKVTARGGRAGHITSDDGVLDFDIVMPNAKKEGQTGTNP EQLFAAGYAACFGGALEHVAKEQNIEIDSEIEGQVSLMKDESDGGFKIGVTLVVNTKD LDREKAQELVNAAHEFCPYSKATRGNVDVKLELK*" gene 1382020..1382430 /gene="ohrB" /locus_tag="BSU_13160" /old_locus_tag="BSU13160" downshifts 1382408 /Source="Nicolas_upshifts" /id="D719" /incds=0 /nref=7 /ntot=145 /MaxReadThrough="8.17185" /MaxDrop="4.0663" /score="17.6512157" /energy="-12.1" /TU="U1062" /idTUdmin="U1062" /TUdmin="-855" /isTUend="FALSE" CDS 1382457..1382627 /gene="ykzN" /locus_tag="BSU_13169" /old_locus_tag="BSU13169" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_003097717.1" /db_xref="EnsemblGenomes-Gn:BSU13169" /db_xref="EnsemblGenomes-Tr:CAX52607" /db_xref="UniProtKB/Swiss-Prot:C0H400" /translation="MFFGVGHAGRAQIYDKTSEKRLKHAFKPKVTDEAGGWHGVCRAE LRVYAVLYLHRA*" gene 1382457..1382627 /gene="ykzN" /locus_tag="BSU_13169" /old_locus_tag="BSU13169" S_feature 1382628..1383305 /Source="Nicolas_S_feature" /locus_tag="new_1382628_1383305" /HighExp="Etha, Salt, M9-stat, Sw, B60, LPhT, B36, Heat, Gly, BC" /AntisenseName="guaD" /AntisenseCor="-5.7732597431508298E-2" /AntisenseRegPval="-0.5" /CDS_PredictionProba="NA" /TUshortSig="SigB" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S468" CDS complement(1382677..1383147) /gene="guaN" /locus_tag="BSU_13170" /old_locus_tag="BSU13170" /EC_number="3.5.4.3" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:11101664, 15180998" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11101664, 15180998; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="guanine deaminase" /protein_id="NP_389200.1" /db_xref="EnsemblGenomes-Gn:BSU13170" /db_xref="EnsemblGenomes-Tr:CAB13174" /db_xref="GOA:O34598" /db_xref="InterPro:IPR002125" /db_xref="InterPro:IPR016192" /db_xref="InterPro:IPR016193" /db_xref="PDB:1TIY" /db_xref="PDB:1WKQ" /db_xref="SubtiList:BG13240" /db_xref="UniProtKB/Swiss-Prot:O34598" /translation="MNHETFLKRAVTLACEGVNAGIGGPFGAVIVKDGAIIAEGQNNV TTSNDPTAHAEVTAIRKACKVLGAYQLDDCILYTSCEPCPMCLGAIYWARPKAVFYAA EHTDAAEAGFDDSFIYKEIDKPAEERTIPFYQVTLTEHLSPFQAWRNFANKKEY*" gene complement(1382677..1383147) /gene="guaN" /locus_tag="BSU_13170" /old_locus_tag="BSU13170" downshifts complement(1382701) /Source="Nicolas_upshifts" /id="D720" /incds=0 /nref=25 /ntot=112 /MaxReadThrough="0.698199999999999" /MaxDrop="4.30578" /score="-6.41557266" /energy="-13.5" /TU="NA" /idTUdmin="U1063" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(1383169..1383188) /Source="Nicolas_upshift_promotors" /id="U1063" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.434565434565435" /psig="0.933066933066933" /xcortree=790 /SigmaFactorBS="atcccccaaatactttgtttattttgcacttttttaagAATG ttctttgcattctttTCGGCTATACTAATAACACTctattgacaggagggattgggat g" /listShort="guaD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1383185) /Source="Nicolas_upshifts" /id="U1063" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.434565434565435" /psig="0.933066933066933" /xcortree=790 /SigmaFactorBS="atcccccaaatactttgtttattttgcacttttttaagAATG ttctttgcattctttTCGGCTATACTAATAACACTctattgacaggagggattgggat g" /listShort="guaD" /GFF_Attribute="listLong" S_feature complement(1383187..1383294) /Source="Nicolas_S_feature" /locus_tag="new_1383187_1383294_c" /HighExp="BMM, MG 10, MG 15, MG 5, MG t5, GM 25, B36, Gly, B60, GM 90" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="Sig-, SigA" /TUshortPSig="0.044, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S469" promotor_-35 complement(1383204..1383207) /Source="Nicolas_upshift_promotors" /id="U1063" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.434565434565435" /psig="0.933066933066933" /xcortree=790 /SigmaFactorBS="atcccccaaatactttgtttattttgcacttttttaagAATG ttctttgcattctttTCGGCTATACTAATAACACTctattgacaggagggattgggat g" /listShort="guaD" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 1383263 /Source="Nicolas_upshifts" /id="D721" /incds=0 /nref=9 /ntot=34 /MaxReadThrough="0.95942" /MaxDrop="5.95076" /score="15.2916843" /energy="-11.5" /TU="NA" /idTUdmin="U1062" /TUdmin=0 /isTUend="TRUE" CDS complement(1383320..1385608) /gene="metE" /locus_tag="BSU_13180" /old_locus_tag="BSU13180" /EC_number="2.1.1.14" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:8755891, 10094622, 12910260, 16086852, 16194229, 17012790, 17611193, 21749987, 22938038, 24313874" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8755891, 10094622, 12910260, 16086852, 16194229, 17012790, 17611193, 21749987, 22938038, 24313874; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="cobalamin-independent methionine synthase" /protein_id="NP_389201.2" /db_xref="EnsemblGenomes-Gn:BSU13180" /db_xref="EnsemblGenomes-Tr:CAB13175" /db_xref="GOA:P80877" /db_xref="InterPro:IPR002629" /db_xref="InterPro:IPR006276" /db_xref="InterPro:IPR013215" /db_xref="SubtiList:BG12616" /db_xref="UniProtKB/Swiss-Prot:P80877" /translation="MTTIKTSNLGFPRIGLNREWKKALEAYWKGSTDKDTFLKQIDEL FLSAVKTQIDQQIDVVPVSDFTQYDHVLDTAVSFNWIPKRFRHLTDATDTYFAIARGI KDAVSSEMTKWFNTNYHYIVPEYDESIEFRLTRNKQLEDYRRIKQEYGVETKPVIVGP YTFVTLAKGYEPSEAKAIQKRLVPLYVQLLKELEEEGVKWVQIDEPALVTASSEDVRG AKELFESITSELSSLNVLLQTYFDSVDAYEELISYPVQGIGLDFVHDKGRNLEQLKTH GFPTDKVLAAGVIDGRNIWKADLEERLDAVLDILSIAKVDELWIQPSSSLLHVPVAKH PDEHLEKDLLNGLSYAKEKLAELTALKEGLVSGKAAISEEIQQAKADIQALKQFATGA NSEQKKELEQLTDKDFKRPIPFEERLALQNESLGLPLLPTTTIGSFPQSAEVRSARQK WRKAEWSDEQYQNFINAETKRWIDIQEELELDVLVHGEFERTDMVEYFGEKLAGFAFT KYAWVQSYGSRCVRPPVIYGDVEFIEPMTVKDTVYAQSLTSKHVKGMLTGPVTILNWS FPRNDISRKEIAFQIGLALRKEVKALEDAGIQIIQVDEPALREGLPLKTRDWDEYLTW AAEAFRLTTSSVKNETQIHTHMCYSNFEDIVDTINDLDADVITIEHSRSHGGFLDYLK NHPYLKGLGLGVYDIHSPRVPSTEEMYNIIVDALAVCPTDRFWVNPDCGLKTRQQEET VAALKNMVEAAKQARAQQTQLV*" gene complement(1383320..1385608) /gene="metE" /locus_tag="BSU_13180" /old_locus_tag="BSU13180" downshifts complement(1383339) /Source="Nicolas_upshifts" /id="D722" /incds=0 /nref=212 /ntot=239 /MaxReadThrough="5.25958" /MaxDrop="7.50935" /score="29.3354648" /energy="-11.5" /TU="U1064,U1065" /idTUdmin="U1063" /TUdmin="-638" /isTUend="FALSE" S_feature complement(1385609..1385671) /Source="Nicolas_S_feature" /locus_tag="new_1385609_1385671_c" /HighExp="MG 15, MG 5, MG t5, BMM, T-1.40H, MG 25, MG 10, GM 25, Mal, Etha" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="Sig-, SigA, SigA" /TUshortPSig="0.044, 1, 0.587" /TUlongSig="NA" /TUlongPSig="NA" /label="S470" promotor_no_box complement(1385631..1385731) /Source="Nicolas_upshift_promotors" /id="U1064" /multdbtbs="-" /comp="M21" /sig="Sig-" /pcomp="0.332667332667333" /psig="0.043956043956044" /xcortree=3023 /SigmaFactorBS="agtgttttacgtagaaaagcctctttctctcatgggaaagag gctttttgttgtgagaaaacctcttagcagcctgtatccgcgggtgaaagagagtgtt t" /listShort="S470, metE, S469, guaD" /GFF_Attribute="listLong" /label="promotor_no_box" upshifts complement(1385671) /Source="Nicolas_upshifts" /id="U1064" /multdbtbs="-" /comp="M21" /sig="Sig-" /pcomp="0.332667332667333" /psig="0.043956043956044" /xcortree=3023 /SigmaFactorBS="agtgttttacgtagaaaagcctctttctctcatgggaaagag gctttttgttgtgagaaaacctcttagcagcctgtatccgcgggtgaaagagagtgtt t" /listShort="S470, metE, S469, guaD" /GFF_Attribute="listLong" misc_RNA complement(1385736..1385891) /gene="mswB" /locus_tag="BSU_misc_RNA_18" /product="S-adenosylmethionine riboswitch" /experiment="publication(s) with functional evidences, PMID:10094622, 12626738, 12910260, 17381305, 18039762, 22543867" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10094622, 12626738, 12910260, 17381305, 18039762, 22543867; Product type n : RNA" /function="16.3: Control" gene complement(1385736..1385891) /gene="mswB" /locus_tag="BSU_misc_RNA_18" downshifts complement(1385737) /Source="Nicolas_upshifts" /id="D723" /incds=0 /nref=55 /ntot=106 /MaxReadThrough="8.12248" /MaxDrop="6.4813" /score="24.0596293" /energy="-16.2" /TU="U1065,U1066" /idTUdmin="U1066" /TUdmin="-308" /isTUend="FALSE" promotor_-10 complement(1385924..1385943) /Source="Nicolas_upshift_promotors" /id="U1065" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.992007992007992" /psig=1 /xcortree=2888 /SigmaFactorBS="acatcatgtaaataaaaatttcaaattctaTGTTGACAatga atttgaattacTGTTAAGATTACCAACAAATgattcaacttttcaaaaaattaataac a" /listShort="NA, S470, metE, S469, guaD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1385936) /Source="Nicolas_upshifts" /id="U1065" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.992007992007992" /psig=1 /xcortree=2888 /SigmaFactorBS="acatcatgtaaataaaaatttcaaattctaTGTTGACAatga atttgaattacTGTTAAGATTACCAACAAATgattcaacttttcaaaaaattaataac a" /listShort="NA, S470, metE, S469, guaD" /GFF_Attribute="listLong" S_feature complement(1385938..1386023) /Source="Nicolas_S_feature" /locus_tag="new_1385938_1386023_c" /HighExp="BT, BC, B36, M9-stat, T5.0H, S3, S6, T4.0H, S5, T0.30H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.587" /TUlongSig="NA" /TUlongPSig="NA" /label="S471" promotor_-35 complement(1385959..1385966) /Source="Nicolas_upshift_promotors" /id="U1065" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.992007992007992" /psig=1 /xcortree=2888 /SigmaFactorBS="acatcatgtaaataaaaatttcaaattctaTGTTGACAatga atttgaattacTGTTAAGATTACCAACAAATgattcaacttttcaaaaaattaataac a" /listShort="NA, S470, metE, S469, guaD" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(1386024..1386983) /gene="ispA" /locus_tag="BSU_13190" /old_locus_tag="BSU13190" /EC_number="3.4.21.-" /function="16.6: Maintain" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:3087947, 14680823, 23569278" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 3087947, 14680823, 23569278; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="intracellular serine protease" /protein_id="NP_389202.1" /db_xref="EnsemblGenomes-Gn:BSU13190" /db_xref="EnsemblGenomes-Tr:CAB13176" /db_xref="GOA:P11018" /db_xref="InterPro:IPR000209" /db_xref="InterPro:IPR015500" /db_xref="InterPro:IPR022398" /db_xref="InterPro:IPR023827" /db_xref="InterPro:IPR023828" /db_xref="InterPro:IPR034202" /db_xref="InterPro:IPR036852" /db_xref="SubtiList:BG10674" /db_xref="UniProtKB/Swiss-Prot:P11018" /translation="MNGEIRLIPYVTNEQIMDVNELPEGIKVIKAPEMWAKGVKGKNI KVAVLDTGCDTSHPDLKNQIIGGKNFTDDDGGKEDAISDYNGHGTHVAGTIAANDSNG GIAGVAPEASLLIVKVLGGENGSGQYEWIINGINYAVEQKVDIISMSLGGPSDVPELK EAVKNAVKNGVLVVCAAGNEGDGDERTEELSYPAAYNEVIAVGSVSVARELSEFSNAN KEIDLVAPGENILSTLPNKKYGKLTGTSMAAPHVSGALALIKSYEEESFQRKLSESEV FAQLIRRTLPLDIAKTLAGNGFLYLTAPDELAEKAEQSHLLTL*" gene complement(1386024..1386983) /gene="ispA" /locus_tag="BSU_13190" /old_locus_tag="BSU13190" S_feature complement(1386984..1387035) /Source="Nicolas_S_feature" /locus_tag="new_1386984_1387035_c" /HighExp="BT, B36, BC, T5.0H, M9-stat, T0.30H, T3.30H, T3.0H, T4.0H, S6" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.587" /TUlongSig="NA" /TUlongPSig="NA" /label="S472" promotor_-10 complement(1387028..1387047) /Source="Nicolas_upshift_promotors" /id="U1066" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.358641358641359" /psig="0.587412587412587" /xcortree=465 /SigmaFactorBS="tgtatcctattttttcaaaatgcttcaaatggcTCTGTCCga gcgcttgctttTTTCATATAATATGAGGCAAcacccttgaatccacttgcaagcataa a" /listShort="S472, ispA, S471, NA, S470, metE" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1387040) /Source="Nicolas_upshifts" /id="U1066" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.358641358641359" /psig="0.587412587412587" /xcortree=465 /SigmaFactorBS="tgtatcctattttttcaaaatgcttcaaatggcTCTGTCCga gcgcttgctttTTTCATATAATATGAGGCAAcacccttgaatccacttgcaagcataa a" /listShort="S472, ispA, S471, NA, S470, metE" /GFF_Attribute="listLong" promotor_-35 complement(1387061..1387067) /Source="Nicolas_upshift_promotors" /id="U1066" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.358641358641359" /psig="0.587412587412587" /xcortree=465 /SigmaFactorBS="tgtatcctattttttcaaaatgcttcaaatggcTCTGTCCga gcgcttgctttTTTCATATAATATGAGGCAAcacccttgaatccacttgcaagcataa a" /listShort="S472, ispA, S471, NA, S470, metE" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1387152..1387155 /Source="Nicolas_upshift_promotors" /id="U1067" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.3996003996004" /psig=1 /xcortree=2359 /SigmaFactorBS="gaattagtaatcttcaaaatattggatggcttcaacatgtat gaCTGGgattcaactgtaagtCAAGTTATAATAGTGTTGGGgaaaggagcagtgtcat g" /listShort="rsbRB" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 1387168 /Source="Nicolas_upshifts" /id="U1067" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.3996003996004" /psig=1 /xcortree=2359 /SigmaFactorBS="gaattagtaatcttcaaaatattggatggcttcaacatgtat gaCTGGgattcaactgtaagtCAAGTTATAATAGTGTTGGGgaaaggagcagtgtcat g" /listShort="rsbRB" /GFF_Attribute="listLong" promotor_-10 1387171..1387190 /Source="Nicolas_upshift_promotors" /id="U1067" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.3996003996004" /psig=1 /xcortree=2359 /SigmaFactorBS="gaattagtaatcttcaaaatattggatggcttcaacatgtat gaCTGGgattcaactgtaagtCAAGTTATAATAGTGTTGGGgaaaggagcagtgtcat g" /listShort="rsbRB" /GFF_Attribute="listLong" /label="promotor_-10" CDS 1387206..1388039 /gene="rsbRB" /locus_tag="BSU_13200" /old_locus_tag="BSU13200" /function="16.8: Protect" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:15312768, 15583165, 17158665" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15312768, 15583165, 17158665; Product type f: factor" /codon_start=1 /transl_table=11 /product="component of the anxiosome (stressosome)" /protein_id="NP_389203.1" /db_xref="EnsemblGenomes-Gn:BSU13200" /db_xref="EnsemblGenomes-Tr:CAB13177" /db_xref="InterPro:IPR002645" /db_xref="InterPro:IPR036513" /db_xref="SubtiList:BG12609" /db_xref="UniProtKB/Swiss-Prot:O34860" /translation="MKLNEKLYAFFSEHVEQMAEEWIETMEESDPNSLYALHNATVTE ELKEQDREFYRHLNYMYVLPEKQFLEEFQEWVIELTNDQKHLDTPVQYVIREFMRNRR LYTKYFEKFAEENESAFEPGEKQKWADLIVKVFDFTIYTFVDHAEMNAKQQLNAQREM ILELSSPVITLSKSTALLPLVGDIDTERAKFILENTLQACAKRRVEHLLIDLSGVVVV DTMVAHQIFKLIEALNLIGVRSTLSGIRPEIAQTAVQLGIDFSNITIKTNLAQALNYH Q*" gene 1387206..1388039 /gene="rsbRB" /locus_tag="BSU_13200" /old_locus_tag="BSU13200" downshifts 1388015 /Source="Nicolas_upshifts" /id="D724" /incds=0 /nref=219 /ntot=254 /MaxReadThrough="3.01586" /MaxDrop="6.07238" /score="22.2655638" /energy="-12.1" /TU="NA" /idTUdmin="U1067" /TUdmin=0 /isTUend="TRUE" CDS complement(1388070..1388834) /gene="thiX" /locus_tag="BSU_13210" /old_locus_tag="BSU13210" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:15849754, 16291685, 16356850, 16850406, 18931129" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15849754, 16291685, 16356850, 16850406, 18931129; Product type t : transporter" /codon_start=1 /transl_table=11 /product="thiamine transporter, transmembrane T component" /protein_id="NP_389204.1" /db_xref="EnsemblGenomes-Gn:BSU13210" /db_xref="EnsemblGenomes-Tr:CAB13178" /db_xref="GOA:O34572" /db_xref="InterPro:IPR003339" /db_xref="SubtiList:BG13248" /db_xref="UniProtKB/Swiss-Prot:O34572" /translation="MKQPLHLINPTVKAAAVFCCVVMLSFIYNPYTPACFYIIIVAGV LLAAGIPLKKWLLFTIPFLILAFGCVWTAAVFGKVPTTPDNFLFQAGPISINSDNVSV GISLGFRILCFSALSMMFVFTTDPILFMLSLVQQCRLSPKLAYGVIAGFRFLPLLKDE VQLIQQAHKIRGGAAESGIINKISALKRYTIPLLASAIRKAERTALAMESKGFTGSRN RTYYRTLSVNRRDWVFFCLVLLLFAGSFLVSLCFAS*" gene complement(1388070..1388834) /gene="thiX" /locus_tag="BSU_13210" /old_locus_tag="BSU13210" downshifts complement(1388091) /Source="Nicolas_upshifts" /id="D725" /incds=0 /nref=143 /ntot=164 /MaxReadThrough="0.824010000000001" /MaxDrop="6.67697" /score="34.7739353" /energy="-12.1" /TU="NA" /idTUdmin="U1069" /TUdmin=0 /isTUend="TRUE" CDS complement(1388809..1390452) /gene="thiW" /locus_tag="BSU_13220" /old_locus_tag="BSU13220" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:15849754, 16291685, 16356850, 16850406, 18931129" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15849754, 16291685, 16356850, 16850406, 18931129; Product type t : transporter" /codon_start=1 /transl_table=11 /product="thiamine ABC transporter (ATP-binding subunit)" /protein_id="NP_389205.2" /db_xref="EnsemblGenomes-Gn:BSU13220" /db_xref="EnsemblGenomes-Tr:CAB13179" /db_xref="GOA:O34362" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR017871" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG13249" /db_xref="UniProtKB/Swiss-Prot:O34362" /translation="MQAFDELLTVEQLSFSYEEDEKPVFQDISFELQKGECVLLLGPS GCGKSSLALCLNGLYPEACDGIQSGHVFLFQKPVTDAETSETITQHAGVVFQDPDQQF CMLTVEDEIAFGLENLQIPKEEMTEKINAVLEKLRITHLKEKMISTLSGGQKQKVALA CILAMEPELIILDEPTSLLDPFSAREFVHLMKDLQREKGFSLLVIEHQLDEWAPWIER TIVLDKSGKKALDGLTKNLFQHEAETLKKLGIAIPKVCHLQEKLSMPFTLSKEMLFKE PIPAGHVKKKKAPSGESVLEVSSLSFARGQQAIFKDISFSLREGSLTALVGPNGTGKS TLLSVLASLMKPQSGKILLYDQPLQKYKEKELRKRMGFVFQNPEHQFVTDTVYDELLF GQKANAETEKKAQHLLQRFGLAHLADHHPFAISQGQKRRLSVATMLMHDVKVLLLDEP TFGQDARTAAECMEMIQRIKAEGTAVLMITHDMELVSSYADSVLVLHDTGLAFDGSPA QLFSQETGLVQKAKLTLPLLYEWMAFQEEVRDEATVTSH*" gene complement(1388809..1390452) /gene="thiW" /locus_tag="BSU_13220" /old_locus_tag="BSU13220" CDS complement(1390439..1391038) /gene="thiV" /locus_tag="BSU_13230" /old_locus_tag="BSU13230" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:15849754, 16291685, 16356850, 16850406, 27447050, 22720735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15849754, 16291685, 16356850, 16850406, 27447050, 22720735; Product type t : transporter" /codon_start=1 /transl_table=11 /product="thiamine transporter, permease component" /protein_id="NP_389206.2" /db_xref="EnsemblGenomes-Gn:BSU13230" /db_xref="EnsemblGenomes-Tr:CAB13180" /db_xref="GOA:O34738" /db_xref="InterPro:IPR017195" /db_xref="PDB:5EDL" /db_xref="SubtiList:BG13250" /db_xref="UniProtKB/Swiss-Prot:O34738" /translation="MKSWKVKEIVIMSVISIVFAVVYLLFTHFGNVLAGMFGPIAYEP IYGIWFIVSVIAAYMIRKPGAALVSEIIAALVECLLGNPSGPMVIVIGIVQGLGAEAV FLATRWKAYSLPVLMLAGMGSSVASFIYDLFVSGYAAYSPGYLLIMLVIRLISGALLA GLLGKAVSDSLAYTGVLNGMALGKELKKKRKRASEHASL*" gene complement(1390439..1391038) /gene="thiV" /locus_tag="BSU_13230" /old_locus_tag="BSU13230" CDS complement(1391040..1391642) /gene="thiU" /locus_tag="BSU_13240" /old_locus_tag="BSU13240" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:15451668, 16291685, 16356850, 20471400" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15451668, 16291685, 16356850, 20471400; Product type f: factor" /codon_start=1 /transl_table=11 /product="thiamine-binding protein (oxidation stress protein)" /protein_id="NP_389207.1" /db_xref="EnsemblGenomes-Gn:BSU13240" /db_xref="EnsemblGenomes-Tr:CAB13181" /db_xref="GOA:O34911" /db_xref="InterPro:IPR011522" /db_xref="InterPro:IPR015835" /db_xref="InterPro:IPR029756" /db_xref="PDB:1S7H" /db_xref="PDB:1S99" /db_xref="PDB:1SBR" /db_xref="SubtiList:BG13251" /db_xref="UniProtKB/Swiss-Prot:O34911" /translation="MEHICGTSRIAGFRFSLYPMTDDFISVIKSALKKTDTSKVWTKT DHISTVLRGSIDHVFDAAKAIYLHAANSEQHIVMNGTFSIGCPGDTQGDTYLSKGDKR VNEDAVRGLKAEAPCQFALYPMNEPDYMGLIMEAVDIAKAQGTFVQGVHYASELDGDA HDVFSTLEAVFRMAEQQTNHITMTVNLSANSPSRKNRKQG*" gene complement(1391040..1391642) /gene="thiU" /locus_tag="BSU_13240" /old_locus_tag="BSU13240" downshifts complement(1391720) /Source="Nicolas_upshifts" /id="D726" /incds=0 /nref=28 /ntot=88 /MaxReadThrough="7.47395" /MaxDrop="5.73297" /score="19.7469386" /energy="-10.9" /TU="U1069" /idTUdmin="U1069" /TUdmin="-3629" /isTUend="FALSE" misc_RNA complement(1391739..1391851) /gene="tswB" /locus_tag="BSU_misc_RNA_19" /product="thiamine pyrophosphate riboswitch" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 11470904, 12410317, 15862294, 16728979, 16962976, 17307816, 18179415, 18776013; Product type n: RNA" /function="16.3: Control" gene complement(1391739..1391851) /gene="tswB" /locus_tag="BSU_misc_RNA_19" promotor_-35 1391852..1391855 /Source="Nicolas_upshift_promotors" /id="U1068" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.425574425574426" /psig="0.987012987012987" /xcortree=1848 /SigmaFactorBS="tcagccaaaacagcacccctagtgctttccGTATacaatttt ttattttGACATCATAATAGATGATAAgaatcattttgtaaacaacgaaatcattttt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(1391866..1391885) /Source="Nicolas_upshift_promotors" /id="U1069" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.917082917082917" /psig=1 /xcortree=2882 /SigmaFactorBS="accatcctctcccgtccctatatgaaaaaaatgatttcgtTG TTTACAaaatgattcttatcATCTATTATGATGTCAAAATaaaaaattgtatacggaa a" /listShort="NA, thiU, thiV, thiW, thiX" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-10 1391871..1391890 /Source="Nicolas_upshift_promotors" /id="U1068" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.425574425574426" /psig="0.987012987012987" /xcortree=1848 /SigmaFactorBS="tcagccaaaacagcacccctagtgctttccGTATacaatttt ttattttGACATCATAATAGATGATAAgaatcattttgtaaacaacgaaatcattttt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1391882 /Source="Nicolas_upshifts" /id="U1068" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.425574425574426" /psig="0.987012987012987" /xcortree=1848 /SigmaFactorBS="tcagccaaaacagcacccctagtgctttccGTATacaatttt ttattttGACATCATAATAGATGATAAgaatcattttgtaaacaacgaaatcattttt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" upshifts complement(1391887) /Source="Nicolas_upshifts" /id="U1069" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.917082917082917" /psig=1 /xcortree=2882 /SigmaFactorBS="accatcctctcccgtccctatatgaaaaaaatgatttcgtTG TTTACAaaatgattcttatcATCTATTATGATGTCAAAATaaaaaattgtatacggaa a" /listShort="NA, thiU, thiV, thiW, thiX" /GFF_Attribute="listLong" promotor_-35 complement(1391900..1391907) /Source="Nicolas_upshift_promotors" /id="U1069" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.917082917082917" /psig=1 /xcortree=2882 /SigmaFactorBS="accatcctctcccgtccctatatgaaaaaaatgatttcgtTG TTTACAaaatgattcttatcATCTATTATGATGTCAAAATaaaaaattgtatacggaa a" /listShort="NA, thiU, thiV, thiW, thiX" /GFF_Attribute="listLong" /label="promotor_-35" CDS 1391953..1392639 /gene="ykoG" /locus_tag="BSU_13250" /old_locus_tag="BSU13250" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:11717295" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11717295; Product type r: regulator" /codon_start=1 /transl_table=11 /product="two-component response regulator [YkoH]" /protein_id="NP_389208.1" /db_xref="EnsemblGenomes-Gn:BSU13250" /db_xref="EnsemblGenomes-Tr:CAB13182" /db_xref="GOA:O34903" /db_xref="InterPro:IPR001789" /db_xref="InterPro:IPR001867" /db_xref="InterPro:IPR011006" /db_xref="InterPro:IPR036388" /db_xref="SubtiList:BG13252" /db_xref="UniProtKB/Swiss-Prot:O34903" /translation="MEKGHILIVEDEEKIARVLQLELEYEGYSVTIKHNGTEGLDAAA EGGYSLVLLDVMLPGLSGLEVLRRLRKTDSQTPVILLTARDSIPDKVTGLDIGANDYV TKPFEIEELLARIRAALRQNGTKTEDIGTFLTYDDLRVNEKTREVRRGDKEVELTPRE FDLLVYMLKHPQQVLTREQILSSVWGFDYIGDTNVVDVYIRYIRKKLDYPYEKQLIHT IRGVGYAIKG*" gene 1391953..1392639 /gene="ykoG" /locus_tag="BSU_13250" /old_locus_tag="BSU13250" CDS 1392643..1394007 /gene="ykoH" /locus_tag="BSU_13260" /old_locus_tag="BSU13260" /EC_number="2.7.13.3" /function="16.12: Sense" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:11717295" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11717295; Product type rc: receptor" /codon_start=1 /transl_table=11 /product="two-component sensor histidine kinase [YkoG]" /protein_id="NP_389209.1" /db_xref="EnsemblGenomes-Gn:BSU13260" /db_xref="EnsemblGenomes-Tr:CAB13183" /db_xref="GOA:O34638" /db_xref="InterPro:IPR003594" /db_xref="InterPro:IPR003660" /db_xref="InterPro:IPR003661" /db_xref="InterPro:IPR004358" /db_xref="InterPro:IPR005467" /db_xref="InterPro:IPR036097" /db_xref="InterPro:IPR036890" /db_xref="SubtiList:BG13253" /db_xref="UniProtKB/Swiss-Prot:O34638" /translation="MKLKTKIHLYTSISLLILLILVHTAVYLIFSSALTSKDAARLAD ETDNIAEALRAAETEGVALQDMLQAYLPANGMVRVVNGDQKAVMTITKEKAYKDFPLS FHSGETADVRKPDGKLFAEAAVPVIWTDGQVVSLQLVERLENTEESLFLLKIILIAAS AAVCIASFFAGSLLARRIINPIRRLMITMKDIQRDKEFKTISLEGQSNDELYQMGLTF NEMAMMLKEHYDKQQQFVQDASHELKTPLTIIESYSSLMKRWGAKKPEVLEESIEAIH SEAVHMKKLTNQLLALAKSHQGLEVDLKTIDLIKAARAVMQTLQSVYQRDILLETDKE SLLVKADEERIKQLLTILLDNAIKYSEKPIEMSAGTRNGRPFLSVRDEGIGIPEEHIP HLFERFYRADEARNRKTGGTGLGLSIAKQIADEHGIELSVKSKPGQGTAVTMQFSEQN GGGR*" gene 1392643..1394007 /gene="ykoH" /locus_tag="BSU_13260" /old_locus_tag="BSU13260" CDS 1394004..1394684 /gene="ykoI" /locus_tag="BSU_13270" /old_locus_tag="BSU13270" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 11717295; Product type m : membranecomponent" /codon_start=1 /transl_table=11 /product="conserved membrane protein of unknown function" /protein_id="NP_389210.1" /db_xref="EnsemblGenomes-Gn:BSU13270" /db_xref="EnsemblGenomes-Tr:CAB13184" /db_xref="GOA:O34551" /db_xref="InterPro:IPR014722" /db_xref="InterPro:IPR025711" /db_xref="SubtiList:BG13254" /db_xref="UniProtKB/Swiss-Prot:O34551" /translation="MTKTIKTVSFAAAAILVVIICTFLIIRQTHENVLSKETVVKKVE ASYEGKVTKATQSKDKKTYDITLENPKGTYFVKADAISADILSMNRVKAVNPSAMTEK EAEHLALERVPGTVKKQTRQSQVATYTIQKEDGKTYEVKVDMQAKTVLSADQISSKDQ QKTPITKKEAKTIAERKTGGTADDADLEESEGTLIFEVDVDLPDNKEATVKINAYTGK VANIVYED*" gene 1394004..1394684 /gene="ykoI" /locus_tag="BSU_13270" /old_locus_tag="BSU13270" promotor_-35 1394713..1394718 /Source="Nicolas_upshift_promotors" /id="U1070" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.352647352647353" /psig="0.748251748251748" /xcortree=658 /SigmaFactorBS="aagactgacggtttctcatcaaattctcatcttgctCTCGTT ttcctttcatgttgaGTATGTAAACTGTACTCATacaaaacaaaggagggctcacaaa t" /listShort="ykoJ, ykzD" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1394734..1394752 /Source="Nicolas_upshift_promotors" /id="U1070" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.352647352647353" /psig="0.748251748251748" /xcortree=658 /SigmaFactorBS="aagactgacggtttctcatcaaattctcatcttgctCTCGTT ttcctttcatgttgaGTATGTAAACTGTACTCATacaaaacaaaggagggctcacaaa t" /listShort="ykoJ, ykzD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1394737 /Source="Nicolas_upshifts" /id="U1070" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.352647352647353" /psig="0.748251748251748" /xcortree=658 /SigmaFactorBS="aagactgacggtttctcatcaaattctcatcttgctCTCGTT ttcctttcatgttgaGTATGTAAACTGTACTCATacaaaacaaaggagggctcacaaa t" /listShort="ykoJ, ykzD" /GFF_Attribute="listLong" CDS 1394776..1395288 /gene="ykoJ" /locus_tag="BSU_13280" /old_locus_tag="BSU13280" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 17209068; Product type ph: phenotype" /codon_start=1 /transl_table=11 /product="putative exported protein" /protein_id="NP_389211.1" /db_xref="EnsemblGenomes-Gn:BSU13280" /db_xref="EnsemblGenomes-Tr:CAB13185" /db_xref="InterPro:IPR025711" /db_xref="SubtiList:BG13255" /db_xref="UniProtKB/Swiss-Prot:O35012" /translation="MLKKKWMVGLLAGCLAAGGFSYNAFATENNENRQASSKTDALTE QEAEAIAKTVVDGTVEDIDRDLYNGKEVYEVEIEKEGEDYDVYVDIHTKQALNDPLKE KAEQVAITKEEAEEIALKQTGGTVTESKLDEDDGAYIYEMEIQTKQGTETEFEISAKD GRIIKQEIDD*" gene 1394776..1395288 /gene="ykoJ" /locus_tag="BSU_13280" /old_locus_tag="BSU13280" downshifts 1395274 /Source="Nicolas_upshifts" /id="D727" /incds=0 /nref=52 /ntot=228 /MaxReadThrough="3.74302" /MaxDrop="6.03059" /score="28.1760649" /energy="-13.7" /TU="U1070" /idTUdmin="U1070" /TUdmin="-198" /isTUend="FALSE" promotor_-35 1395319..1395325 /Source="Nicolas_upshift_promotors" /id="U1071" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=922 /SigmaFactorBS="gatgactaatcaaaacccccgctgcagcgggggtttttcATG ATAAgaaaccttcttttGGACAATCTAAGtagaaaaggaggcgaaacgcatggaaaag a" /listShort="ykzD" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1395339..1395350 /Source="Nicolas_upshift_promotors" /id="U1071" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=922 /SigmaFactorBS="gatgactaatcaaaacccccgctgcagcgggggtttttcATG ATAAgaaaccttcttttGGACAATCTAAGtagaaaaggaggcgaaacgcatggaaaag a" /listShort="ykzD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1395340 /Source="Nicolas_upshifts" /id="U1071" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=922 /SigmaFactorBS="gatgactaatcaaaacccccgctgcagcgggggtttttcATG ATAAgaaaccttcttttGGACAATCTAAGtagaaaaggaggcgaaacgcatggaaaag a" /listShort="ykzD" /GFF_Attribute="listLong" CDS 1395371..1395508 /gene="ykzD" /locus_tag="BSU_13290" /old_locus_tag="BSU13290" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_389212.1" /db_xref="EnsemblGenomes-Gn:BSU13290" /db_xref="EnsemblGenomes-Tr:CAB13186" /db_xref="InterPro:IPR022608" /db_xref="SubtiList:BG13332" /db_xref="UniProtKB/Swiss-Prot:O34405" /translation="MEKKEEQYINQAEYVPHPTKEGEYALFLHETYHLLSEDDETQTT E*" gene 1395371..1395508 /gene="ykzD" /locus_tag="BSU_13290" /old_locus_tag="BSU13290" downshifts 1395481 /Source="Nicolas_upshifts" /id="D728" /incds=0 /nref=7 /ntot=31 /MaxReadThrough="1.81189" /MaxDrop="3.56977" /score="-4.52149284" /energy="-5.9" /TU="NA" /idTUdmin="U1070" /TUdmin=9 /isTUend="TRUE" promotor_-35 1395567..1395574 /Source="Nicolas_upshift_promotors" /id="U1072" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.55044955044955" /psig=1 /xcortree=2735 /SigmaFactorBS="tccgtaattgtgatgtaagcgcatttattacttttttGAGTT GACatagcttgtttttTTCTGTAATCTCAGTGTGTCaattcaattaggaacttcgtta g" /listShort="S473, S474, mgtE" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1395588..1395607 /Source="Nicolas_upshift_promotors" /id="U1072" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.55044955044955" /psig=1 /xcortree=2735 /SigmaFactorBS="tccgtaattgtgatgtaagcgcatttattacttttttGAGTT GACatagcttgtttttTTCTGTAATCTCAGTGTGTCaattcaattaggaacttcgtta g" /listShort="S473, S474, mgtE" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 1395590..1395909 /Source="Nicolas_S_feature" /locus_tag="new_1395590_1395909" /HighExp="LBGstat, LBGtran, M40t45, MG 25, Mt0, Salt, MG 45, LPhT, BMM, MG t5" /AntisenseName="ykzO" /AntisenseCor="-0.16301119751811899" /AntisenseRegPval="-2.1" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S473" upshifts 1395590 /Source="Nicolas_upshifts" /id="U1072" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.55044955044955" /psig=1 /xcortree=2735 /SigmaFactorBS="tccgtaattgtgatgtaagcgcatttattacttttttGAGTT GACatagcttgtttttTTCTGTAATCTCAGTGTGTCaattcaattaggaacttcgtta g" /listShort="S473, S474, mgtE" /GFF_Attribute="listLong" misc_RNA 1395622..1395775 /gene="swmG" /locus_tag="BSU_misc_RNA_68" /product="magnesium riboswitch" /experiment="publication(s) with functional evidences, PMID:15096624, 17803910, 21315082, 28455443" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15096624, 17803910, 21315082, 28455443; Product type n: RNA" /function="16.12: Sense" /function="16.3: Control" gene 1395622..1395775 /gene="swmG" /locus_tag="BSU_misc_RNA_68" promotor_-35 1395887..1395896 /Source="Nicolas_upshift_promotors" /id="U1073" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.876123876123876" /psig="0.876123876123876" /xcortree=1632 /SigmaFactorBS="ccaatcaaaggaggtgcggagtatggattctccccaTTCGAG TCAAtctgaagaagtaCCCATATACTATGACAGCAAgacaattgattacacgatgagg a" /listShort="S474, mgtE" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1395909..1395928 /Source="Nicolas_upshift_promotors" /id="U1073" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.876123876123876" /psig="0.876123876123876" /xcortree=1632 /SigmaFactorBS="ccaatcaaaggaggtgcggagtatggattctccccaTTCGAG TCAAtctgaagaagtaCCCATATACTATGACAGCAAgacaattgattacacgatgagg a" /listShort="S474, mgtE" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 1395911..1396012 /Source="Nicolas_S_feature" /locus_tag="new_1395911_1396012" /HighExp="LBGstat, LBGtran, M40t45, Mt0, LPhT, Paraq, MG t5, MG 25, MG 60, Salt" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.99773400000000001" /TUshortSig="SigK, SigA" /TUshortPSig="0.876, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S474" upshifts 1395911 /Source="Nicolas_upshifts" /id="U1073" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.876123876123876" /psig="0.876123876123876" /xcortree=1632 /SigmaFactorBS="ccaatcaaaggaggtgcggagtatggattctccccaTTCGAG TCAAtctgaagaagtaCCCATATACTATGACAGCAAgacaattgattacacgatgagg a" /listShort="S474, mgtE" /GFF_Attribute="listLong" CDS 1396013..1397368 /gene="mgtE" /locus_tag="BSU_13300" /old_locus_tag="BSU13300" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:15096624, 22970223, 24415722, 24968120, 25182490" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15096624, 22970223, 24415722, 24968120, 25182490; Product type t : transporter" /codon_start=1 /transl_table=11 /product="magnesium transporter" /protein_id="NP_389213.1" /db_xref="EnsemblGenomes-Gn:BSU13300" /db_xref="EnsemblGenomes-Tr:CAB13187" /db_xref="GOA:O34442" /db_xref="InterPro:IPR000644" /db_xref="InterPro:IPR006667" /db_xref="InterPro:IPR006668" /db_xref="InterPro:IPR006669" /db_xref="InterPro:IPR036739" /db_xref="SubtiList:BG13256" /db_xref="UniProtKB/Swiss-Prot:O34442" /translation="MVQNMTYDELILRIIILLRDGKIRDFRSVIDELQPYDMAFIFKE MPEKHRARYLSYLTVDDITDMIGELEREFQLVVLNKVGKTKATLAMNKMDNDDLAQLL EEMDEELKEQLLSSMEASESKAVQLLMNYPADSAGRMMTNRYVWIPQHYTVKDAVVKL KSFAEIAESINYLYVINESKQLVGVLSYRDLILGEPEEKVQDLMFTRVISADALQDQE EVARLIERYDFLAIPVVEENNVLVGIVTVDDIIDVVIREADEDYEKFAASGKDITFDT KAYVAAYRRLPWLILLLFIGLISGSIISYFEDALKQVVALAFFMPMVSGMTGNTGTQS LAVVIRGLSKEEMNKKTIVRLIFREFRTSIFIGAVCSVLIAIVSIIWQGNALLGFVVA SSLFLTLIIGTMSGTIIPIILHKLKVDPAIASGPLITTLNDILSLLIYFGIATAFIHS L*" gene 1396013..1397368 /gene="mgtE" /locus_tag="BSU_13300" /old_locus_tag="BSU13300" downshifts 1397359 /Source="Nicolas_upshifts" /id="D729" /incds=0 /nref=160 /ntot=239 /MaxReadThrough="1.02063" /MaxDrop="7.38933" /score="-4.14569718" /energy="-8.9" /TU="NA" /idTUdmin="U1072" /TUdmin="-4" /isTUend="TRUE" CDS complement(1397411..1397743) /gene="tnrA" /locus_tag="BSU_13310" /old_locus_tag="BSU13310" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:10231480, 12823818, 15916606, 16547045, 17085574, 17183219, 21435182, 23535029, 26635369" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10231480, 12823818, 15916606, 16547045, 17085574, 17183219, 21435182, 23535029, 26635369; Product type r: regulator" /codon_start=1 /transl_table=11 /product="nitrogen sensing transcriptional regulator" /protein_id="NP_389214.1" /db_xref="EnsemblGenomes-Gn:BSU13310" /db_xref="EnsemblGenomes-Tr:CAB13188" /db_xref="GOA:Q45666" /db_xref="InterPro:IPR000551" /db_xref="InterPro:IPR009061" /db_xref="PDB:4S0R" /db_xref="SubtiList:BG11805" /db_xref="UniProtKB/Swiss-Prot:Q45666" /translation="MTTEDHSYKDKKVISIGIVSELTGLSVRQIRYYEERKLIYPQRS SRGTRKYSFADVERLMDIANKREDGVQTAEILKDMRKKEQMLKNDPQVRKKMLEGQLN AHFRYKNR*" gene complement(1397411..1397743) /gene="tnrA" /locus_tag="BSU_13310" /old_locus_tag="BSU13310" promotor_-10 complement(1397759..1397778) /Source="Nicolas_upshift_promotors" /id="U1074" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.625374625374625" /psig="0.99100899100899" /xcortree=1709 /SigmaFactorBS="tttgatgttagaaaatatgacaagcgtcagGTTTTTtctctt tgttttttaTATACTATTATCAAAAGACAtccaggggtggaaaaatgaccacagaaga t" /listShort="tnrA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1397769) /Source="Nicolas_upshifts" /id="U1074" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.625374625374625" /psig="0.99100899100899" /xcortree=1709 /SigmaFactorBS="tttgatgttagaaaatatgacaagcgtcagGTTTTTtctctt tgttttttaTATACTATTATCAAAAGACAtccaggggtggaaaaatgaccacagaaga t" /listShort="tnrA" /GFF_Attribute="listLong" S_feature complement(1397771..1398159) /Source="Nicolas_S_feature" /locus_tag="new_1397771_1398159_c" /HighExp="M9-stat, BC, LoTm, T1.30H, T0.30H, T2.0H, S8, C30, T4.0H, T2.30H" /AntisenseName="ykzB" /AntisenseCor="-3.3870578787867499E-2" /AntisenseRegPval="-0.2" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.92" /TUlongSig="NA" /TUlongPSig="NA" /label="S475" promotor_-35 complement(1397794..1397799) /Source="Nicolas_upshift_promotors" /id="U1074" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.625374625374625" /psig="0.99100899100899" /xcortree=1709 /SigmaFactorBS="tttgatgttagaaaatatgacaagcgtcagGTTTTTtctctt tgttttttaTATACTATTATCAAAAGACAtccaggggtggaaaaatgaccacagaaga t" /listShort="tnrA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_no_box 1397831..1397931 /Source="Nicolas_upshift_promotors" /id="U1075" /multdbtbs="-" /comp="M21" /sig="Sig-" /pcomp="0.375624375624376" /psig="0.295704295704296" /xcortree=315 /SigmaFactorBS="agaagatttttgaaaaaatacggaagaaaaattaacaagaat aatgcgtaacacccaagcgcgttttatcctttatgtaacgaatcaaacgaggaggaag g" /listShort="ykzB, ykoL" /GFF_Attribute="listLong" /label="promotor_no_box" upshifts 1397891 /Source="Nicolas_upshifts" /id="U1075" /multdbtbs="-" /comp="M21" /sig="Sig-" /pcomp="0.375624375624376" /psig="0.295704295704296" /xcortree=315 /SigmaFactorBS="agaagatttttgaaaaaatacggaagaaaaattaacaagaat aatgcgtaacacccaagcgcgttttatcctttatgtaacgaatcaaacgaggaggaag g" /listShort="ykzB, ykoL" /GFF_Attribute="listLong" CDS 1397938..1398093 /gene="ykzB" /locus_tag="BSU_13320" /old_locus_tag="BSU13320" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 10671441" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_389215.1" /db_xref="EnsemblGenomes-Gn:BSU13320" /db_xref="EnsemblGenomes-Tr:CAB13189" /db_xref="SubtiList:BG13330" /db_xref="UniProtKB/Swiss-Prot:O34923" /translation="MEEEKAVSLAKEIIELDIKRDEMLETFMQLAGEQAFQLLRSVQN GQYRKSS*" gene 1397938..1398093 /gene="ykzB" /locus_tag="BSU_13320" /old_locus_tag="BSU13320" promotor_-35 1398102..1398109 /Source="Nicolas_upshift_promotors" /id="U1076" /multdbtbs="SigA" /comp="M6" /sig="Sig-" /pcomp="0.985014985014985" /psig="0.006993006993007" /xcortree=10 /SigmaFactorBS="caataccgaaaatcttcgtaaacataaatTCTTTACAttaga tTCATACCACGTTCATTTAaaaagagtatcttttgtataggatacctcaaaatgaagg a" /listShort="ykoL, S476, ykoM" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1398116..1398133 /Source="Nicolas_upshift_promotors" /id="U1076" /multdbtbs="SigA" /comp="M6" /sig="Sig-" /pcomp="0.985014985014985" /psig="0.006993006993007" /xcortree=10 /SigmaFactorBS="caataccgaaaatcttcgtaaacataaatTCTTTACAttaga tTCATACCACGTTCATTTAaaaagagtatcttttgtataggatacctcaaaatgaagg a" /listShort="ykoL, S476, ykoM" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1398133 /Source="Nicolas_upshifts" /id="U1076" /multdbtbs="SigA" /comp="M6" /sig="Sig-" /pcomp="0.985014985014985" /psig="0.006993006993007" /xcortree=10 /SigmaFactorBS="caataccgaaaatcttcgtaaacataaatTCTTTACAttaga tTCATACCACGTTCATTTAaaaagagtatcttttgtataggatacctcaaaatgaagg a" /listShort="ykoL, S476, ykoM" /GFF_Attribute="listLong" promotor_-10 complement(1398144..1398163) /Source="Nicolas_upshift_promotors" /id="U1077" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.394605394605395" /psig="0.92007992007992" /xcortree=3030 /SigmaFactorBS="tcgttctttttctaaagcggatttcaataaattactCATAGC GtcctccttcatttTGAGGTATCCTATACAAAAGatactctttttaaatgaacgtggt a" /listShort="S475, tnrA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1398159) /Source="Nicolas_upshifts" /id="U1077" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.394605394605395" /psig="0.92007992007992" /xcortree=3030 /SigmaFactorBS="tcgttctttttctaaagcggatttcaataaattactCATAGC GtcctccttcatttTGAGGTATCCTATACAAAAGatactctttttaaatgaacgtggt a" /listShort="S475, tnrA" /GFF_Attribute="listLong" promotor_-35 complement(1398177..1398183) /Source="Nicolas_upshift_promotors" /id="U1077" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.394605394605395" /psig="0.92007992007992" /xcortree=3030 /SigmaFactorBS="tcgttctttttctaaagcggatttcaataaattactCATAGC GtcctccttcatttTGAGGTATCCTATACAAAAGatactctttttaaatgaacgtggt a" /listShort="S475, tnrA" /GFF_Attribute="listLong" /label="promotor_-35" CDS 1398181..1398363 /gene="ykoL" /locus_tag="BSU_13330" /old_locus_tag="BSU13330" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 10671441" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_389216.1" /db_xref="EnsemblGenomes-Gn:BSU13330" /db_xref="EnsemblGenomes-Tr:CAB13190" /db_xref="SubtiList:BG13257" /db_xref="UniProtKB/Swiss-Prot:O34763" /translation="MSNLLKSALEKERRHYSEKLYQIGVYNKEVMNKMTISELRKEYA YFFRSITNHKNYPYTR*" gene 1398181..1398363 /gene="ykoL" /locus_tag="BSU_13330" /old_locus_tag="BSU13330" downshifts 1398331 /Source="Nicolas_upshifts" /id="D730" /incds=0 /nref=2 /ntot=8 /MaxReadThrough="3.83398" /MaxDrop="4.6651" /score="19.6832496" /energy="-11.2" /TU="U1076" /idTUdmin="U1075" /TUdmin=0 /isTUend="TRUE" promotor_-35 1398388..1398396 /Source="Nicolas_upshift_promotors" /id="U1078" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.996003996003996" /psig="0.996003996003996" /xcortree=361 /SigmaFactorBS="atacaagataatgtataaggatttttttgcttttaGAAGGAA TTtctcgaattaTAGCGAATACGTATAGTAAgggactgaactcttattatatgtaagg g" /listShort="S476, ykoM" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1398407..1398425 /Source="Nicolas_upshift_promotors" /id="U1078" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.996003996003996" /psig="0.996003996003996" /xcortree=361 /SigmaFactorBS="atacaagataatgtataaggatttttttgcttttaGAAGGAA TTtctcgaattaTAGCGAATACGTATAGTAAgggactgaactcttattatatgtaagg g" /listShort="S476, ykoM" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 1398413..1398495 /Source="Nicolas_S_feature" /locus_tag="new_1398413_1398495" /HighExp="T3.0H, M9-stat, T1.30H, T2.30H, Lbstat, T3.30H, Lbtran, S2, T4.0H, T2.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigH, Sig-" /TUshortPSig="0.996, 0.00699" /TUlongSig="NA" /TUlongPSig="NA" /label="S476" upshifts 1398413 /Source="Nicolas_upshifts" /id="U1078" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.996003996003996" /psig="0.996003996003996" /xcortree=361 /SigmaFactorBS="atacaagataatgtataaggatttttttgcttttaGAAGGAA TTtctcgaattaTAGCGAATACGTATAGTAAgggactgaactcttattatatgtaagg g" /listShort="S476, ykoM" /GFF_Attribute="listLong" CDS 1398496..1398960 /gene="ykoM" /locus_tag="BSU_13340" /old_locus_tag="BSU13340" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative transcriptional regulator (MarR family)" /protein_id="NP_389217.1" /db_xref="EnsemblGenomes-Gn:BSU13340" /db_xref="EnsemblGenomes-Tr:CAB13191" /db_xref="GOA:O34949" /db_xref="InterPro:IPR000835" /db_xref="InterPro:IPR023187" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG13258" /db_xref="UniProtKB/Swiss-Prot:O34949" /translation="MMRLSFNEEEVERAMNLYRVFARAFKSVSEHSIRDSKEHGFNPT EFAVLELLYTRGPQKLQQIGSRLLLVSGNVTYVIDKLERNGFLVREQDPKDKRSVYAH LTDKGNEYLDKIYPIHALRIARAFSGLSPDEQDQLIVLLKKAGIHSQHLLFR*" gene 1398496..1398960 /gene="ykoM" /locus_tag="BSU_13340" /old_locus_tag="BSU13340" downshifts 1398945 /Source="Nicolas_upshifts" /id="D731" /incds=0 /nref=70 /ntot=210 /MaxReadThrough="2.86787" /MaxDrop="5.38705" /score="24.8730632" /energy="-9.8" /TU="U1078" /idTUdmin="U1078" /TUdmin="-112" /isTUend="FALSE" CDS complement(1398975..1400096) /gene="ykoN" /locus_tag="BSU_13350" /old_locus_tag="BSU13350" /EC_number="2.4.1.-" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative glycosyltransferase" /protein_id="NP_389218.2" /db_xref="EnsemblGenomes-Gn:BSU13350" /db_xref="EnsemblGenomes-Tr:CAB13192" /db_xref="GOA:C0SPB9" /db_xref="InterPro:IPR009695" /db_xref="SubtiList:BG13259" /db_xref="UniProtKB/Swiss-Prot:C0SPB9" /translation="MKNILIFPFLSISTGHHHVADALQAELESQGLAAEKIDIFSHSY RRLEKLSSVAYLKWIQYFPKTYSGIYRLLACGEFQHDKRYFMYEWLFTQQMRHILQEK QPDIAFCTHALPSYLLNRLKPEYPNLTVVNVYTDFFVNQLWGRKNIDYHFVPSTEVKK QLISEGIDQNNIYLTGIPVHQNFEMESADTLQHHPPYTIIITGGSMGVGGILKWVQEL SPGGKILYKILCGRNEKLYSYVKSLHHPLIEAIPYLHSKAEMNRLYEQATGIMTKPGG VTISECLQKRLPVFIYHALPGQEEMNLNLLHERKLVTDMRNWDMQKAEEYIAAFFQSN EQMKEYKKHVNGYLGEMSDRKIKDVLKRIIWKQKNTLLK*" gene complement(1398975..1400096) /gene="ykoN" /locus_tag="BSU_13350" /old_locus_tag="BSU13350" promotor_-35 1399384..1399392 /Source="Nicolas_upshift_promotors" /id="U1079" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.97902097902098" /psig="0.97902097902098" /xcortree=1311 /SigmaFactorBS="cctcaatcaaggggtggtgtaaacttttgacatagGAGTAGA GCttttcgtttctgcCGCATAATATTTTGTATAAGatctttccgcctggcgacagttc c" /listShort="S477, ykoP" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1399406..1399425 /Source="Nicolas_upshift_promotors" /id="U1079" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.97902097902098" /psig="0.97902097902098" /xcortree=1311 /SigmaFactorBS="cctcaatcaaggggtggtgtaaacttttgacatagGAGTAGA GCttttcgtttctgcCGCATAATATTTTGTATAAGatctttccgcctggcgacagttc c" /listShort="S477, ykoP" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 1399409..1400187 /Source="Nicolas_S_feature" /locus_tag="new_1399409_1400187" /HighExp="S6, S8, S7, S5, BT, B36, S4, S3, Pyr, G/S" /AntisenseName="ykoN" /AntisenseCor="0.84084970563549499" /AntisenseRegPval="-72.400000000000006" /CDS_PredictionProba="NA" /TUshortSig="SigK" /TUshortPSig="0.979" /TUlongSig="NA" /TUlongPSig="NA" /label="S477" upshifts 1399409 /Source="Nicolas_upshifts" /id="U1079" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.97902097902098" /psig="0.97902097902098" /xcortree=1311 /SigmaFactorBS="cctcaatcaaggggtggtgtaaacttttgacatagGAGTAGA GCttttcgtttctgcCGCATAATATTTTGTATAAGatctttccgcctggcgacagttc c" /listShort="S477, ykoP" /GFF_Attribute="listLong" promotor_-10 complement(1400125..1400136) /Source="Nicolas_upshift_promotors" /id="U1080" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.99100899100899" /psig="0.99100899100899" /xcortree=819 /SigmaFactorBS="aaggaaacaagttttcatcttttcaccttccttatgatcaaa aacaccCTTATATtttgtgaacgttctCCTCAAAATATAgttgccatatttttttagg a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1400145) /Source="Nicolas_upshifts" /id="U1080" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.99100899100899" /psig="0.99100899100899" /xcortree=819 /SigmaFactorBS="aaggaaacaagttttcatcttttcaccttccttatgatcaaa aacaccCTTATATtttgtgaacgttctCCTCAAAATATAgttgccatatttttttagg a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(1400151..1400157) /Source="Nicolas_upshift_promotors" /id="U1080" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.99100899100899" /psig="0.99100899100899" /xcortree=819 /SigmaFactorBS="aaggaaacaagttttcatcttttcaccttccttatgatcaaa aacaccCTTATATtttgtgaacgttctCCTCAAAATATAgttgccatatttttttagg a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" CDS 1400188..1400739 /gene="ykoP" /locus_tag="BSU_13360" /old_locus_tag="BSU13360" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_389219.2" /db_xref="EnsemblGenomes-Gn:BSU13360" /db_xref="EnsemblGenomes-Tr:CAB13193" /db_xref="SubtiList:BG13260" /db_xref="UniProtKB/Swiss-Prot:O34495" /translation="MKTCFLSIWRVVDPIYFFFSRLSLIDNDQKSVFRVRLTKYKGHH VVLSDGTHIRKNDVLVKIHLHNIKLIRELQSIESAVRKGIIIYQKVYQSMPLLLDYIN NHKKSEKIKGIIGITMLDKGVERLGFDVITPVNPFYRCFKKVSHVPILYLTSKPVSLR HLPNSSYLFISKEKLQKTYQKKD*" gene 1400188..1400739 /gene="ykoP" /locus_tag="BSU_13360" /old_locus_tag="BSU13360" downshifts 1400707 /Source="Nicolas_upshifts" /id="D732" /incds=0 /nref=4 /ntot=25 /MaxReadThrough="3.31887" /MaxDrop="3.7149" /score="-2.92393792" /energy="-7" /TU="U1079" /idTUdmin="U1079" /TUdmin="-242" /isTUend="FALSE" CDS complement(1400767..1401579) /gene="ykoQ" /locus_tag="BSU_13370" /old_locus_tag="BSU13370" /EC_number="3.1.-.-" /function="16.11: Scavenge (Catabolism)" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative metallophosphoesterase" /protein_id="NP_389220.1" /db_xref="EnsemblGenomes-Gn:BSU13370" /db_xref="EnsemblGenomes-Tr:CAB13194" /db_xref="GOA:O35040" /db_xref="InterPro:IPR004843" /db_xref="InterPro:IPR029052" /db_xref="SubtiList:BG13261" /db_xref="UniProtKB/Swiss-Prot:O35040" /translation="MFTILLSLAILVFVPFLYKANRNTKDVKVNTISIDQKDGLPARK KLNILHLSDLHLENISVSPEELYHLTKDQPVDIIALTGDFLDRKRNIPKLAGYLNALQ KLKPAYGMYAVFGNHDYVLKEEDFQRLKRVLEENGCITLQNEHVRIETAAGPVNIIGI DDYSTNRSNITGSYQSLENGYHLVLTHDPNIILDMKDVHYDYLLSGHFHGGQIHWPKP YHLVKMGKLVRMNMIKGLHYHHDKPFYISEGLGQTGVNIRVGSRPEVTFHQI*" gene complement(1400767..1401579) /gene="ykoQ" /locus_tag="BSU_13370" /old_locus_tag="BSU13370" promotor_-10 complement(1401539..1401558) /Source="Nicolas_upshift_promotors" /id="U1081" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.485514485514486" /psig="0.997002997002997" /xcortree=2484 /SigmaFactorBS="acttactatactgatagaagggaggggatatattttGTTTAC aatcttactttcaTTGGCCATACTCGTATTTGTgccatttctatataaagcgaaccgc a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1401553) /Source="Nicolas_upshifts" /id="U1081" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.485514485514486" /psig="0.997002997002997" /xcortree=2484 /SigmaFactorBS="acttactatactgatagaagggaggggatatattttGTTTAC aatcttactttcaTTGGCCATACTCGTATTTGTgccatttctatataaagcgaaccgc a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(1401572..1401577) /Source="Nicolas_upshift_promotors" /id="U1081" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.485514485514486" /psig="0.997002997002997" /xcortree=2484 /SigmaFactorBS="acttactatactgatagaagggaggggatatattttGTTTAC aatcttactttcaTTGGCCATACTCGTATTTGTgccatttctatataaagcgaaccgc a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1401680..1401686 /Source="Nicolas_upshift_promotors" /id="U1082" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=939 /SigmaFactorBS="aattaatgggtagagacaggttgaaaaacggattgtcatatg aTGAATGAtttggaagggaaaAGGGATAATAAAttttgacacatgaggcagaacatgc c" /listShort="S478, ykoS, ykoT" /GFF_Attribute="listLong" /label="promotor_-35" S_feature 1401697..1401771 /Source="Nicolas_S_feature" /locus_tag="new_1401697_1401771" /HighExp="S5, S6, S7, S4, S8, T5.0H, ferm, nit, S3, Pyr" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigGF" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S478" upshifts 1401697 /Source="Nicolas_upshifts" /id="U1082" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=939 /SigmaFactorBS="aattaatgggtagagacaggttgaaaaacggattgtcatatg aTGAATGAtttggaagggaaaAGGGATAATAAAttttgacacatgaggcagaacatgc c" /listShort="S478, ykoS, ykoT" /GFF_Attribute="listLong" promotor_-10 1401700..1401711 /Source="Nicolas_upshift_promotors" /id="U1082" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=939 /SigmaFactorBS="aattaatgggtagagacaggttgaaaaacggattgtcatatg aTGAATGAtttggaagggaaaAGGGATAATAAAttttgacacatgaggcagaacatgc c" /listShort="S478, ykoS, ykoT" /GFF_Attribute="listLong" /label="promotor_-10" CDS 1401772..1403466 /gene="ykoS" /locus_tag="BSU_13380" /old_locus_tag="BSU13380" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative integral membrane protein" /protein_id="NP_389221.1" /db_xref="EnsemblGenomes-Gn:BSU13380" /db_xref="EnsemblGenomes-Tr:CAB13195" /db_xref="GOA:O34830" /db_xref="SubtiList:BG13262" /db_xref="UniProtKB/Swiss-Prot:O34830" /translation="MLRLMRQQKKETYYLWIALFLLLLYVSPLFILKEDAHIRVHDNL DSNIAWYKVLADSGEIVGKVDAAIPQIINGLPRDAFGTEWSGIVWLHAFFSSMTAYAI SQTVTRVVAFFGMYVLLKKHIIPEPKAAFIRIGVSLAFALTPFWPSGMLSTLGYPLAL WAFLNIRKGDISWREWLTLGLLPLYSSFVLGFFFFLAGMACFWLYDAITKRRWNLMFL GSIAFMTSIYLFVEYRLVYSMLFEHAPMHRIEFISSRHDVWHSLRLSIKNFVYGHNHV MTVHTVVILPILMVVFAALLFKRNRTKPENVYLFLCVLNYGLSLWYAFWFNKIWAVPK QKFAFLAEFNFARFHFLRPLVIYVSFALALYLIWRMGKGWKWLVYAAVAAQLMVLAPF NEEYTYGVHYNAPTFREFYASEQFKEIKEYIGRPQDSYRVASIGLHPSIAQYNGFYTL DTYNNLYPLSYKYEFRKIIEKELEKNSRLKQYFDEWGSRCYLFVDELGKRYDFKKNSK KTINNLQLNTDVFKKMGGRYIFSSVPIMNAEQNHLALVKTFDHKDSAWRIYLYETR*" gene 1401772..1403466 /gene="ykoS" /locus_tag="BSU_13380" /old_locus_tag="BSU13380" CDS 1403479..1404492 /gene="ykoT" /locus_tag="BSU_13390" /old_locus_tag="BSU13390" /EC_number="2.-.-.-" /function="16.2: Construct biomass (Anabolism)" /function="16.13: Shape" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative glycosyltransferase" /protein_id="NP_389222.1" /db_xref="EnsemblGenomes-Gn:BSU13390" /db_xref="EnsemblGenomes-Tr:CAB13196" /db_xref="GOA:O34755" /db_xref="InterPro:IPR001173" /db_xref="InterPro:IPR029044" /db_xref="SubtiList:BG13263" /db_xref="UniProtKB/Swiss-Prot:O34755" /translation="MKQSQPVLTIVVPCFNEEEVFQETSHQLTEVVDDLIEEKLIAED SKILFVDDGSKDRTWALIAMESIRNKKVTGLKLACNVGHQKALLAGLHKAKNRSDCVI SIDADLQDDISVIRDFMLKYHEGCEIVYGVRRSRKTDTFFKRTTALGFYRLMNKLGIK LIYNHADFRLMNKRSLEELERYPEANLFLRGIVPMIGFKSAEVLYDRKERFAGKTKYP LKKMLSFAFNGITSFSVAPIRFFTLLGFVLFFLSAVAGIGAFIQKLLGHTNAGWASLI ISIWFLGGLQLMGIGIIGEYIGTIFSEVKRRPKYAIDIDLYNEQLSPLQRQEKERLEK KYS*" gene 1403479..1404492 /gene="ykoT" /locus_tag="BSU_13390" /old_locus_tag="BSU13390" downshifts 1404477 /Source="Nicolas_upshifts" /id="D733" /incds=0 /nref=13 /ntot=35 /MaxReadThrough="0.53349" /MaxDrop="4.80671" /score="19.4012674" /energy="-13.7" /TU="NA" /idTUdmin="U1082" /TUdmin=8 /isTUend="TRUE" CDS complement(1404518..1406353) /gene="ligD" /locus_tag="BSU_13400" /old_locus_tag="BSU13400" /EC_number="6.5.1.1" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:12215643, 16497325, 17293412, 23691176, 25355514, 26826709" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12215643, 16497325, 17293412, 23691176, 25355514, 26826709; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="ATP-dependent DNA ligase subunit; 5'-2-deoxyribose-5-phosphate (dRP) lyase" /protein_id="NP_389223.1" /db_xref="EnsemblGenomes-Gn:BSU13400" /db_xref="EnsemblGenomes-Tr:CAB13197" /db_xref="GOA:O34398" /db_xref="InterPro:IPR012310" /db_xref="InterPro:IPR014143" /db_xref="InterPro:IPR014145" /db_xref="InterPro:IPR014146" /db_xref="InterPro:IPR033652" /db_xref="SubtiList:BG13264" /db_xref="UniProtKB/Swiss-Prot:O34398" /translation="MAFTMQPVLTSSPPIGAEWRYEVKYDGYRCILRIHSSGVTLTSR NGVELSSTFPEITQFAKTAFQHLEKELPLTLDGEIVCLVNPCRADFEHLQVRGRLKRP DKIQESANARPCCFLAFDLLERSGEDVTLLSYLDRKKSLRELISAAKLPASPDPYAKE TIQSIPCYDHFDQLWEMVIKYDGEGIVAKKTNSKWLEKKRSSDWLKYKNFKQAYVCIT GFNPNNGFLTVSVLKNGIMTPIASVSHGMRDEEKSAIREIMEQHGHQTPSGEFTLEPS ICAAVQYLTILQGTLREVSFIGFEFQMDWTECTYAQVIRHSKPVHPKLQFTSLDKIIF EKNKKTKEDFIQYMIEVSDYLLPFLKNRAVTVIRYPHGSRSESFFQKNKPDYAPDFVQ SFYDGSHEHIVCEDMSTLLWLCNQLALEFHVPFQTIKSRRPAEIVIDLDPPSRDDFLM AVQAANELKRLLDSFGITSYPKLSGNKGIQLYIPLSPEAFTYEETRQFTQLIAEYCTN AFPELFTTERLIKNRHCKLYLDYLQHAEGKTIICPYSTRGNELGTVAAPLYWHEVQSS LTPALFTIDTVIDRIKKQGCPFFDFYRNPQDEPLSAILHQLKKKS*" gene complement(1404518..1406353) /gene="ligD" /locus_tag="BSU_13400" /old_locus_tag="BSU13400" downshifts complement(1404567) /Source="Nicolas_upshifts" /id="D734" /incds=0 /nref=10 /ntot=54 /MaxReadThrough="0.67916" /MaxDrop="5.08051" /score="-8.48510187" /energy="-13.7" /TU="NA" /idTUdmin="U1083" /TUdmin=0 /isTUend="TRUE" CDS complement(1406357..1407292) /gene="ligV" /locus_tag="BSU_13410" /old_locus_tag="BSU13410" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:11095673, 12215643, 16497325, 16780573, 23691176, 25355514" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11095673, 12215643, 16497325, 16780573, 23691176, 25355514; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="ATP-dependent DNA ligase subunit Ku; AP/deoxyribose 5'-phosphate (5'-dRP)-lyase" /protein_id="NP_389224.1" /db_xref="EnsemblGenomes-Gn:BSU13410" /db_xref="EnsemblGenomes-Tr:CAB13198" /db_xref="GOA:O34859" /db_xref="InterPro:IPR006164" /db_xref="InterPro:IPR009187" /db_xref="InterPro:IPR016194" /db_xref="SubtiList:BG13265" /db_xref="UniProtKB/Swiss-Prot:O34859" /translation="MNRTPSLHTKEKKGFIDMHTMWKGSISFGLVNIPIKLYAATEDK DIKLRSLHKEDHAPIKYEKVCTNCEKTLSPDEIVKGYEYVKGKYVVLTDEDLKSLKQE HEEKAVEIVDFVQLQEIDPIYFNRSYFVGPGDNGTKAYTLLREALRSTGKIGIANMTI RSKQQLAILRVYENCIVMESIHYPDEVRSAAQVPGVPDQSNVNDKELQTAITLIDELT AKFEPEKYEDTYRQALLQRVNDKLENKETAVTPDKAPPREDVIDLVSALQASIDRTRR PNRETPAAAPAQAAEPKGAGDKKQKTTRKKASGTS*" gene complement(1406357..1407292) /gene="ligV" /locus_tag="BSU_13410" /old_locus_tag="BSU13410" promotor_-10 complement(1407263..1407274) /Source="Nicolas_upshift_promotors" /id="U1083" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=856 /SigmaFactorBS="aataacagcgccggctttttttcacccataagttactaCACA TGAatcgtactccttctCTTCACACTAAAgaaaaaaaggggtttatcgatatgcatac a" /listShort="ykoV, ykoU" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1407273) /Source="Nicolas_upshifts" /id="U1083" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=856 /SigmaFactorBS="aataacagcgccggctttttttcacccataagttactaCACA TGAatcgtactccttctCTTCACACTAAAgaaaaaaaggggtttatcgatatgcatac a" /listShort="ykoV, ykoU" /GFF_Attribute="listLong" promotor_-35 complement(1407289..1407295) /Source="Nicolas_upshift_promotors" /id="U1083" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=856 /SigmaFactorBS="aataacagcgccggctttttttcacccataagttactaCACA TGAatcgtactccttctCTTCACACTAAAgaaaaaaaggggtttatcgatatgcatac a" /listShort="ykoV, ykoU" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(1407329..1409731) /gene="dgcW" /locus_tag="BSU_13420" /old_locus_tag="BSU13420" /EC_number="2.7.7.65" /function="16.3: Control" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:11728710, 17010156, 23893111, 28536559" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11728710, 17010156, 23893111, 28536559; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="diguanylate cyclase" /protein_id="YP_054577.2" /db_xref="EnsemblGenomes-Gn:BSU13420" /db_xref="EnsemblGenomes-Tr:CAB13199" /db_xref="GOA:O34311" /db_xref="InterPro:IPR000160" /db_xref="InterPro:IPR001633" /db_xref="InterPro:IPR005330" /db_xref="InterPro:IPR029787" /db_xref="InterPro:IPR035919" /db_xref="InterPro:IPR035965" /db_xref="SubtiList:BG13266" /db_xref="UniProtKB/Swiss-Prot:O34311" /translation="MEIHVTYNTTLICLSILIACTASYISLELSRKVTINTGLKSKIW LIGGSLIMGFGIWSMHFVGMMAVHMEMPMEYEFMPLMAAIGASVSGSFVSLYFVSRHI LTYYRLLTGSVVLGASIASMHYIGMSAISRVMIIYEPILFTVSIIIAIAASFVSLKIF FDLAVKKHSEHLIFYKGVSSIVMGIGISGMHYTGMLAATFHKDMAPPGSHMEVQTFHW SIFVTLIIFCIQTLLLFSSHADRKFIKQSERIKDNEQRFQSLIVHNIDAIFILSLEGD IISSNHAGEEMISKFGFSMHDWRNYTSLKVKRLFEQVKKDKQAMNSDSDLITEKGQFH LNITLIPVEVNQELDSIYVICKDMTKQYKAEKEIHRMAHYDSLTDLPNRRHAISHLTK VLNREHSLHYNTVVFFLDLNRFKVINDALGHNVGDQLLQFAAKRLSSVVPDNGFIARL GGDEFIIILTDANTGTGEADVLARKIIQKFKKPFKIQDHTLVTSVSIGIAISPKDGTD GLELMKKADMAMYAAKERNKSKYRYYSFSIGNKETVKLNQEMVLREAIENDRFVLHYQ PQFSVKKQKMTGAEALIRLVTPDGQLRPPGEFIGVAEETGLIIDIGKWIIDEACKQAR IWHDKGYDLSVAINISARQFQSKDLIPLIKDTLNKYQLPPQLLEVEVTESMTMDNLNH SKKVLSSLTELGIRISIDDFGTGHSSLSYLKDFPIHRLKIDKSFIDDIQTHPKSEQIT GAIIAMGHQLSLQVIAEGVENAAQKQLLFEKGCDHLQGFFFSRPIPPEQFEQFIIEQP SQ*" gene complement(1407329..1409731) /gene="dgcW" /locus_tag="BSU_13420" /old_locus_tag="BSU13420" downshifts complement(1407361) /Source="Nicolas_upshifts" /id="D735" /incds=0 /nref=13 /ntot=101 /MaxReadThrough="1.93589" /MaxDrop="3.26543" /score="6.55794882" /energy="-9" /TU="NA" /idTUdmin="U1084" /TUdmin=0 /isTUend="TRUE" S_feature complement(1409579..1409781) /Source="Nicolas_S_feature" /locus_tag="new_1409579_1409781_c" /HighExp="Cold, GM 25, GM 10, GM 45, GM 15, GM-0.2, GM-0.1, GM 5, GM 90, Glu" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigD" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S479" promotor_-10 complement(1409770..1409788) /Source="Nicolas_upshift_promotors" /id="U1084" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2819 /SigmaFactorBS="agatctccctcgtatttctatcgttttgaaggCTGAAACTct gcggttaagcaGCCGATAATAAAGAGAGTCaacaagactggaacacacgatacggggg g" /listShort="S479, ykoW" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1409781) /Source="Nicolas_upshifts" /id="U1084" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2819 /SigmaFactorBS="agatctccctcgtatttctatcgttttgaaggCTGAAACTct gcggttaagcaGCCGATAATAAAGAGAGTCaacaagactggaacacacgatacggggg g" /listShort="S479, ykoW" /GFF_Attribute="listLong" promotor_-35 complement(1409802..1409809) /Source="Nicolas_upshift_promotors" /id="U1084" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2819 /SigmaFactorBS="agatctccctcgtatttctatcgttttgaaggCTGAAACTct gcggttaagcaGCCGATAATAAAGAGAGTCaacaagactggaacacacgatacggggg g" /listShort="S479, ykoW" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1409848..1409855 /Source="Nicolas_upshift_promotors" /id="U1085" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.432567432567433" /psig="0.999000999001" /xcortree=1761 /SigmaFactorBS="atagaaatacgagggagatctatttttAGTTCAACtgaccgt gaaaaaTGTGTTAAAATCATCTTGATgttttccgaaaagagaaaaatgtatgatacat a" /listShort="ykoX, ykoY" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1409869..1409888 /Source="Nicolas_upshift_promotors" /id="U1085" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.432567432567433" /psig="0.999000999001" /xcortree=1761 /SigmaFactorBS="atagaaatacgagggagatctatttttAGTTCAACtgaccgt gaaaaaTGTGTTAAAATCATCTTGATgttttccgaaaagagaaaaatgtatgatacat a" /listShort="ykoX, ykoY" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1409881 /Source="Nicolas_upshifts" /id="U1085" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.432567432567433" /psig="0.999000999001" /xcortree=1761 /SigmaFactorBS="atagaaatacgagggagatctatttttAGTTCAACtgaccgt gaaaaaTGTGTTAAAATCATCTTGATgttttccgaaaagagaaaaatgtatgatacat a" /listShort="ykoX, ykoY" /GFF_Attribute="listLong" CDS 1409912..1410577 /gene="ykoX" /locus_tag="BSU_13430" /old_locus_tag="BSU13430" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406, 23687963; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative integral membrane protein" /protein_id="NP_389226.1" /db_xref="EnsemblGenomes-Gn:BSU13430" /db_xref="EnsemblGenomes-Tr:CAB13200" /db_xref="GOA:O34908" /db_xref="InterPro:IPR032816" /db_xref="SubtiList:BG13267" /db_xref="UniProtKB/Swiss-Prot:O34908" /translation="MIHKHETRELVAIEELVMSWIEAFKSLSYFGIFLALSIEFIPAE VVLPLAGYWVSKGDMTLAGVVLAGSLGGVAGPLTLYWIGRYGGRPFLERFGKYLFIKP EALDKSDNFFKKHGGFVAFSGRFLPGIRTLISIPCGIAKMNVWVFSLYTFIAMLPITF VYVYLGVKLGENWKAVGSILDQYMLPIGIAILALFLLYLLMKKRKKRTHSEQLSVFLK NKR*" gene 1409912..1410577 /gene="ykoX" /locus_tag="BSU_13430" /old_locus_tag="BSU13430" promotor_-10 complement(1410446..1410465) /Source="Nicolas_upshift_promotors" /id="U1086" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=1257 /SigmaFactorBS="cctctttttcatcagtaagtagagcaggaacagcgCCAAAAT CGCtatcccgatcggaAGCATATATTGATCAAGAATagagccgactgccttccaattt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1410463) /Source="Nicolas_upshifts" /id="U1086" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=1257 /SigmaFactorBS="cctctttttcatcagtaagtagagcaggaacagcgCCAAAAT CGCtatcccgatcggaAGCATATATTGATCAAGAATagagccgactgccttccaattt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(1410479..1410488) /Source="Nicolas_upshift_promotors" /id="U1086" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=1257 /SigmaFactorBS="cctctttttcatcagtaagtagagcaggaacagcgCCAAAAT CGCtatcccgatcggaAGCATATATTGATCAAGAATagagccgactgccttccaattt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1410572..1410579 /Source="Nicolas_upshift_promotors" /id="U1087" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.952047952047952" /psig=1 /xcortree=600 /SigmaFactorBS="attatctgtatttttgaaaaataaaCGTTGACAaatcactgc gctgcGCATATTATTGACGTATAAAatcatatttcttgaaatcccaaaggggagtagc g" /listShort="ykoY" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1410594..1410613 /Source="Nicolas_upshift_promotors" /id="U1087" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.952047952047952" /psig=1 /xcortree=600 /SigmaFactorBS="attatctgtatttttgaaaaataaaCGTTGACAaatcactgc gctgcGCATATTATTGACGTATAAAatcatatttcttgaaatcccaaaggggagtagc g" /listShort="ykoY" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1410607 /Source="Nicolas_upshifts" /id="U1087" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.952047952047952" /psig=1 /xcortree=600 /SigmaFactorBS="attatctgtatttttgaaaaataaaCGTTGACAaatcactgc gctgcGCATATTATTGACGTATAAAatcatatttcttgaaatcccaaaggggagtagc g" /listShort="ykoY" /GFF_Attribute="listLong" misc_RNA 1410633..1410766 /gene="mnrW" /locus_tag="BSU_misc_RNA_87" /product="manganese ion riboswitch" /experiment="publication(s) with functional evidences, PMID:25794618, 25794619" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 25794618, 25794619; Product type n: RNA" /function="16.12: Sense" /function="16.3: Control" gene 1410633..1410766 /gene="mnrW" /locus_tag="BSU_misc_RNA_87" CDS 1410654..1411628 /gene="ykoY" /locus_tag="BSU_13440" /old_locus_tag="BSU13440" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15096624, 15849754, 16850406, 25794618, 25794619; Product type t : transporter" /codon_start=1 /transl_table=11 /product="putative manganese-related ion transporter" /protein_id="NP_389227.1" /db_xref="EnsemblGenomes-Gn:BSU13440" /db_xref="EnsemblGenomes-Tr:CAB13201" /db_xref="GOA:O34997" /db_xref="InterPro:IPR005496" /db_xref="InterPro:IPR022493" /db_xref="InterPro:IPR036259" /db_xref="SubtiList:BG13268" /db_xref="UniProtKB/Swiss-Prot:O34997" /translation="MYSGNKVVISWIVSIGFVGMPEFMSSKTFALCRQRSFLHGPAGI RSDEEKENNFFGRVSFMDAALLLEYGWVLLVLIGLEGILAADNALVMAVMVKHLPEEK RKKALFYGLAGAFVLRFGSLFAISFLVNVWQVQAIGAIYLLYISASHLLKRYVFKKED THKETKQSGFWPTVLKVELADIAFAVDSILAAVALAVTLPGTSLPKIGGLDGGQFLVI LAGGIIGLVIMRFAASMFVKLLKERPSLETAAFVIVGWVGVKLALYTLAHRDIAVVSE HFIHSGTWKLIFWGVLAAIAVCGWFMSGGKKQPEGAQNEQKNSTRERA*" gene 1410654..1411628 /gene="ykoY" /locus_tag="BSU_13440" /old_locus_tag="BSU13440" downshifts 1410717 /Source="Nicolas_upshifts" /id="D736" /incds=1 /nref=38 /ntot=211 /MaxReadThrough="5.00041" /MaxDrop="4.46498" /score="15.8563987" /energy="-15" /TU="U1085,U1087" /idTUdmin="U1085" /TUdmin="-902" /isTUend="FALSE" downshifts 1411616 /Source="Nicolas_upshifts" /id="D737" /incds=0 /nref=16 /ntot=175 /MaxReadThrough="2.59801" /MaxDrop="4.20782" /score="24.4740487" /energy="-13.7" /TU="NA" /idTUdmin="U1085" /TUdmin="-3" /isTUend="TRUE" promotor_-35 1411738..1411746 /Source="Nicolas_upshift_promotors" /id="U1088" /multdbtbs="SigI" /comp="M2" /sig="SigI" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=1768 /SigmaFactorBS="atctttgttacaaaaaacacgcataaaaCCCCCTTAAttctt tagaaaggCACGAAATCatgtatagaacgtcagaatggtttgtcataattgagacatt g" /listShort="S480, sigI, rsgI, S481" /listLong="htpX" /label="promotor_-35" promotor_-10 1411760..1411768 /Source="Nicolas_upshift_promotors" /id="U1088" /multdbtbs="SigI" /comp="M2" /sig="SigI" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=1768 /SigmaFactorBS="atctttgttacaaaaaacacgcataaaaCCCCCTTAAttctt tagaaaggCACGAAATCatgtatagaacgtcagaatggtttgtcataattgagacatt g" /listShort="S480, sigI, rsgI, S481" /listLong="htpX" /label="promotor_-10" upshifts 1411770 /Source="Nicolas_upshifts" /id="U1088" /multdbtbs="SigI" /comp="M2" /sig="SigI" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=1768 /SigmaFactorBS="atctttgttacaaaaaacacgcataaaaCCCCCTTAAttctt tagaaaggCACGAAATCatgtatagaacgtcagaatggtttgtcataattgagacatt g" /listShort="S480, sigI, rsgI, S481" /listLong="htpX" S_feature 1411773..1411859 /Source="Nicolas_S_feature" /locus_tag="new_1411773_1411859" /HighExp="M9-stat, T1.30H, T1.0H, T0.30H, T2.0H, T2.30H, HiTm, M0t90, T3.0H, HiOs" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.29969800000000002" /TUshortSig="SigI" /TUshortPSig="0.997" /TUlongSig="NA" /TUlongPSig="NA" /label="S480" promotor_-35 1411832..1411839 /Source="Nicolas_upshift_promotors" /id="U1089" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.809190809190809" /psig=1 /xcortree=1635 /SigmaFactorBS="tgagacattggaaatcaatatttctttttctCCTTTGCGaat ccctatcaaaTTAGCTATCATTAATGAGTAgttatagggaggaactgaggtgaaacca g" /listShort="sigI, rsgI, S481" /listLong="htpX" /label="promotor_-35" promotor_-10 1411853..1411872 /Source="Nicolas_upshift_promotors" /id="U1089" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.809190809190809" /psig=1 /xcortree=1635 /SigmaFactorBS="tgagacattggaaatcaatatttctttttctCCTTTGCGaat ccctatcaaaTTAGCTATCATTAATGAGTAgttatagggaggaactgaggtgaaacca g" /listShort="sigI, rsgI, S481" /listLong="htpX" /label="promotor_-10" upshifts 1411861 /Source="Nicolas_upshifts" /id="U1089" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.809190809190809" /psig=1 /xcortree=1635 /SigmaFactorBS="tgagacattggaaatcaatatttctttttctCCTTTGCGaat ccctatcaaaTTAGCTATCATTAATGAGTAgttatagggaggaactgaggtgaaacca g" /listShort="sigI, rsgI, S481" /listLong="htpX" CDS 1411892..1412647 /gene="sigI" /locus_tag="BSU_13450" /old_locus_tag="BSU13450" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:11157964, 12682299, 17185538, 18156261, 21541672, 24125693, 28333276" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11157964, 12682299, 17185538, 18156261, 21541672, 24125693, 28333276; Product type f: factor" /codon_start=1 /transl_table=11 /product="RNA polymerase sigma factor (heat stress responsive)" /protein_id="NP_389228.1" /db_xref="EnsemblGenomes-Gn:BSU13450" /db_xref="EnsemblGenomes-Tr:CAB13218" /db_xref="GOA:O31654" /db_xref="InterPro:IPR007627" /db_xref="InterPro:IPR013325" /db_xref="InterPro:IPR014244" /db_xref="InterPro:IPR014284" /db_xref="SubtiList:BG13269" /db_xref="UniProtKB/Swiss-Prot:O31654" /translation="MKPVLSLLFKLGKKKQTLEKAVESIQKGNKDLQNELIQQYKPFI AKTVSSVCKRYIDEKDDEFSIGLIAFNEAIEKYSPEKGNSLLAFAELIIKRKVIDYIR KEARSAQNINIDLQEGDDQESSQSLIEAELSIDEYRRQIEQEQRREEILYFQKQLKDY GLSFKELLENSPKHTDARQNAIKVAMTLVEHEELAAILYTKKQLPVKQLEQLVSVSRK TIERNRKYIIAMCIIITGDYIYLKDYLKGVLHS*" gene 1411892..1412647 /gene="sigI" /locus_tag="BSU_13450" /old_locus_tag="BSU13450" CDS 1412644..1413789 /gene="rsgI" /locus_tag="BSU_13460" /old_locus_tag="BSU13460" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:17185538, 23199363, 28333276" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 17185538, 23199363, 28333276; Product type f: factor" /codon_start=1 /transl_table=11 /product="sigmaI modulating factor" /protein_id="NP_389229.1" /db_xref="EnsemblGenomes-Gn:BSU13460" /db_xref="EnsemblGenomes-Tr:CAB13219" /db_xref="GOA:O31655" /db_xref="InterPro:IPR024449" /db_xref="SubtiList:BG13272" /db_xref="UniProtKB/Swiss-Prot:O31655" /translation="MRRGIIVEKNKKFVTLLTPDGQFLKAKNDRHSYEIGEEIMLPSE TRMGRRASFFDFFKLRPFKMGIFTMTAIMLFIFIVLPVFSNNKAYAYMTIDINPSVEM ALNSDYEVIELTPLNDEGQKVVNDIDDWEKTDFKKVIDDIITDCSEHGYVKKSKEILI STVYENTEDNTYKKAVKKQLNDVTEKYKTTYRMESLESDMQTREKAKKEGVSTGSYIK SNEKNDNKDIKDDSSKPSGEEDQKSDENEDENTDQTDTQDSKQGDNEQLNDADSGDQK EEKADDQIDDSDKDKKIKESDENTNTEKDGDHEQTPIQDPQDKGNENNGADKGQSQYH RDWNNGEQGKNRSSSRRDNASDRRNPNGYSSDNHSAKNEDSPSAPGE*" gene 1412644..1413789 /gene="rsgI" /locus_tag="BSU_13460" /old_locus_tag="BSU13460" S_feature 1413790..1414949 /Source="Nicolas_S_feature" /locus_tag="new_1413790_1414949" /HighExp="HiTm, G135, G180, C30, G150, Cold, S8, MG 25, H2O2, Lbstat" /AntisenseName="ykrK" /AntisenseCor="0.122248209149143" /AntisenseRegPval="-1.3" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigI" /TUshortPSig="1, 0.997" /TUlongSig="NA" /TUlongPSig="NA" /label="S481" CDS complement(1413800..1413994) /gene="sspD" /locus_tag="BSU_13470" /old_locus_tag="BSU13470" /function="16.5: Explore" /function="16.8: Protect" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:3009397, 3112127, 3121585, 9852018" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 3009397, 3112127, 3121585, 9852018; Product type f: factor" /codon_start=1 /transl_table=11 /product="small acid-soluble spore protein (alpha/beta-type SASP)" /protein_id="NP_389230.1" /db_xref="EnsemblGenomes-Gn:BSU13470" /db_xref="EnsemblGenomes-Tr:CAB13220" /db_xref="GOA:P04833" /db_xref="InterPro:IPR001448" /db_xref="InterPro:IPR018126" /db_xref="SubtiList:BG10788" /db_xref="UniProtKB/Swiss-Prot:P04833" /translation="MASRNKLVVPGVEQALDQFKLEVAQEFGVNLGSDTVARANGSVG GEMTKRLVQQAQSQLNGTTK*" gene complement(1413800..1413994) /gene="sspD" /locus_tag="BSU_13470" /old_locus_tag="BSU13470" downshifts complement(1413807) /Source="Nicolas_upshifts" /id="D738" /incds=0 /nref=24 /ntot=36 /MaxReadThrough="1.67859" /MaxDrop="4.68215" /score="41.3727153" /energy="-15.2" /TU="NA" /idTUdmin="U1090" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(1414037..1414048) /Source="Nicolas_upshift_promotors" /id="U1090" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=868 /SigmaFactorBS="cagaggccggggttttatttttctccacaacaattgccAGCA TAAataaaccccgtataTTTCAAACTAAAtacgcgttaagaatttctttatcgaaaaa g" /listShort="sspD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1414047) /Source="Nicolas_upshifts" /id="U1090" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=868 /SigmaFactorBS="cagaggccggggttttatttttctccacaacaattgccAGCA TAAataaaccccgtataTTTCAAACTAAAtacgcgttaagaatttctttatcgaaaaa g" /listShort="sspD" /GFF_Attribute="listLong" promotor_-35 complement(1414063..1414069) /Source="Nicolas_upshift_promotors" /id="U1090" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=868 /SigmaFactorBS="cagaggccggggttttatttttctccacaacaattgccAGCA TAAataaaccccgtataTTTCAAACTAAAtacgcgttaagaatttctttatcgaaaaa g" /listShort="sspD" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(1414125..1414826) /gene="htpK" /locus_tag="BSU_13480" /old_locus_tag="BSU13480" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:22447908, 23042994" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 22447908, 23042994; Product type r: regulator" /codon_start=1 /transl_table=11 /product="regulator of quality control" /protein_id="NP_389231.1" /db_xref="EnsemblGenomes-Gn:BSU13480" /db_xref="EnsemblGenomes-Tr:CAB13221" /db_xref="InterPro:IPR014975" /db_xref="SubtiList:BG13273" /db_xref="UniProtKB/Swiss-Prot:O31656" /translation="MNIFKLSRTDMVRLLYSLKGQGEHSPLDILVQSANMSAEKAANH LEIPEFLTRYERKKQKKEYGLSTNEIVELGNLCELTSLKSTAIQNWVKRDIKDLIGHP ELGKKYSIEQAVILLIVRDLKSIYDFEHIRAILKVAFNTISDRSDDVISPIAYYESCA YVLDAIHHQDTPSMKESNLQEIAEQETERLRHRFEELNDSQWLKIRQIIAITVLSILT FHIQATAHKMTADIL*" gene complement(1414125..1414826) /gene="htpK" /locus_tag="BSU_13480" /old_locus_tag="BSU13480" downshifts complement(1414159) /Source="Nicolas_upshifts" /id="D739" /incds=0 /nref=174 /ntot=231 /MaxReadThrough="2.96889" /MaxDrop="5.30355" /score="41.3727153" /energy="-15.2" /TU="NA" /idTUdmin="U1091" /TUdmin=0 /isTUend="TRUE" S_feature complement(1414827..1414907) /Source="Nicolas_S_feature" /locus_tag="new_1414827_1414907_c" /HighExp="LBGtran, dia0, LBGexp, Lbexp, Oxctl, G180, M0t45, C90, Paraq, Mt0" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.998" /TUlongSig="NA" /TUlongPSig="NA" /label="S482" promotor_-10 complement(1414899..1414918) /Source="Nicolas_upshift_promotors" /id="U1091" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.911088911088911" /psig="0.998001998001998" /xcortree=2572 /SigmaFactorBS="aacccgtatatttaaattataaaacatcCATTTGAAaatgca aggaattCGACGTATGATGTTAATGTAatttgctgacgcttgaattttgaacttatac a" /listShort="S482, ykrK" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1414907) /Source="Nicolas_upshifts" /id="U1091" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.911088911088911" /psig="0.998001998001998" /xcortree=2572 /SigmaFactorBS="aacccgtatatttaaattataaaacatcCATTTGAAaatgca aggaattCGACGTATGATGTTAATGTAatttgctgacgcttgaattttgaacttatac a" /listShort="S482, ykrK" /GFF_Attribute="listLong" promotor_-35 1414923..1414930 /Source="Nicolas_upshift_promotors" /id="U1092" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.898101898101898" /psig=1 /xcortree=1759 /SigmaFactorBS="cagcaaattacattaacatcatacgtcgaattCCTTGCATtt tcaaatggatgTTTTATAATTTAAATATACGggttcttttgaacttaaaataacggag g" /listShort="htpX" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 complement(1414932..1414939) /Source="Nicolas_upshift_promotors" /id="U1091" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.911088911088911" /psig="0.998001998001998" /xcortree=2572 /SigmaFactorBS="aacccgtatatttaaattataaaacatcCATTTGAAaatgca aggaattCGACGTATGATGTTAATGTAatttgctgacgcttgaattttgaacttatac a" /listShort="S482, ykrK" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1414944..1414963 /Source="Nicolas_upshift_promotors" /id="U1092" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.898101898101898" /psig=1 /xcortree=1759 /SigmaFactorBS="cagcaaattacattaacatcatacgtcgaattCCTTGCATtt tcaaatggatgTTTTATAATTTAAATATACGggttcttttgaacttaaaataacggag g" /listShort="htpX" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1414951 /Source="Nicolas_upshifts" /id="U1092" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.898101898101898" /psig=1 /xcortree=1759 /SigmaFactorBS="cagcaaattacattaacatcatacgtcgaattCCTTGCATtt tcaaatggatgTTTTATAATTTAAATATACGggttcttttgaacttaaaataacggag g" /listShort="htpX" /GFF_Attribute="listLong" CDS 1414997..1415893 /gene="htpX" /locus_tag="BSU_13490" /old_locus_tag="BSU13490" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 11860552, 12081643, 16076848, 16573693, 22447908, 22720735; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="membrane protease" /protein_id="NP_389232.1" /db_xref="EnsemblGenomes-Gn:BSU13490" /db_xref="EnsemblGenomes-Tr:CAB13222" /db_xref="GOA:O31657" /db_xref="InterPro:IPR001915" /db_xref="InterPro:IPR022919" /db_xref="SubtiList:BG13274" /db_xref="UniProtKB/Swiss-Prot:O31657" /translation="MAKRIFLFILTNILVLTTIGIVLSVLSSVTGVGTYFTADGGIDP MALLVFSLVVGFVGSFTSLAISRWMAKTMMGVRVLNPKKHSLSYEEQQLVDRVHRLSR SAGLTKMPEVGIYRSPEVNAFATGPSKRRSLVAVSSGLLEQMDDAAVEGVLAHEVAHI TNGDMVTMTLLQGIVNTFVVFLSRIAAWIASRFVKEDLAPIVHFIAMIIFQIVFSILG SLVVFAYSRHREFHADRGGADLAGKDKMIHALRTLKSYSSRILEDDQTAVQTLKINGK KRSSLFSTHPDLDERIRRLEAK*" gene 1414997..1415893 /gene="htpX" /locus_tag="BSU_13490" /old_locus_tag="BSU13490" downshifts 1415887 /Source="Nicolas_upshifts" /id="D740" /incds=0 /nref=203 /ntot=268 /MaxReadThrough="3.02778" /MaxDrop="6.27746" /score="38.5173589" /energy="-13.4" /TU="NA" /idTUdmin="U1092" /TUdmin=0 /isTUend="TRUE" promotor_-35 1415998..1416002 /Source="Nicolas_upshift_promotors" /id="U1093" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.617382617382617" /psig="0.994005994005994" /xcortree=2515 /SigmaFactorBS="aaaaaataagcaagttaagaaaatgtttcgtaaaagCCTTTa aaaatggacctaatATCTTTAGAATAATTACCGTacttaaaaagagaggcagaaggat t" /listShort="ktrD" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1416018..1416037 /Source="Nicolas_upshift_promotors" /id="U1093" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.617382617382617" /psig="0.994005994005994" /xcortree=2515 /SigmaFactorBS="aaaaaataagcaagttaagaaaatgtttcgtaaaagCCTTTa aaaatggacctaatATCTTTAGAATAATTACCGTacttaaaaagagaggcagaaggat t" /listShort="ktrD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1416022 /Source="Nicolas_upshifts" /id="U1093" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.617382617382617" /psig="0.994005994005994" /xcortree=2515 /SigmaFactorBS="aaaaaataagcaagttaagaaaatgtttcgtaaaagCCTTTa aaaatggacctaatATCTTTAGAATAATTACCGTacttaaaaagagaggcagaaggat t" /listShort="ktrD" /GFF_Attribute="listLong" CDS 1416067..1417416 /gene="ktrD" /locus_tag="BSU_13500" /old_locus_tag="BSU13500" /EC_number="3.6.3.12" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:12562800, 15096624, 15849754, 16850406, 23963175" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12562800, 15096624, 15849754, 16850406, 23963175; Product type t : transporter" /codon_start=1 /transl_table=11 /product="K+-transporting ATPase" /protein_id="NP_389233.1" /db_xref="EnsemblGenomes-Gn:BSU13500" /db_xref="EnsemblGenomes-Tr:CAB13223" /db_xref="GOA:O31658" /db_xref="InterPro:IPR003445" /db_xref="SubtiList:BG13275" /db_xref="UniProtKB/Swiss-Prot:O31658" /translation="MRLKFGKLIQALSPAQLIALYYFLAVTVAVILLSLPAAHKPGAD WTFIDALFTAVSSVSVTGLTVVDTADTFSTIGIFILAFVLQFGGIGIMTLGTFIWLIM GKRIGLKERKLIMVDQNQSQFSGIVNLMKQVLFLILWIEFFGGLILGTYFLTYYDSYQ EAYLHGFFASISATTNGGFDITGNSMIPFRHDYFVQFITMLLIIFGAIGFPVLVEVKD FLFSKHRRYPFTLFTKITTITFGSLVLFGAIGIFALEANHAFAGKSWHDILFLSLFQS TATRSGGLATIDISQLSDSTLFFICALMFIGASPSSVGGGIRTTTFALNLLALFHFAR GNKAVKVFKRELHPADLMKSLVVTMMAILLVFGATLILTITEKHSLLELLFEVCSAFG TTGLSLGITADLSSVGKCVIMIVMFIGRIGILTFLYLIGRKEIEANYHYPKERVIIG* " gene 1416067..1417416 /gene="ktrD" /locus_tag="BSU_13500" /old_locus_tag="BSU13500" downshifts 1417404 /Source="Nicolas_upshifts" /id="D741" /incds=0 /nref=30 /ntot=182 /MaxReadThrough="0.838800000000001" /MaxDrop="4.37717" /score="20.0478288" /energy="-10.7" /TU="NA" /idTUdmin="U1093" /TUdmin="-1" /isTUend="TRUE" promotor_-35 1417465..1417471 /Source="Nicolas_upshift_promotors" /id="U1094" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=834 /SigmaFactorBS="tttgcggtgttttttgattaccaaaaaaaagaTGTGTGCctc ctgttcagttGGAGAACCTAACtccgacaggtgcaatttacgctcctgcatcttaaaa t" /listShort="S483, ykzP, ykzE" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1417485..1417496 /Source="Nicolas_upshift_promotors" /id="U1094" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=834 /SigmaFactorBS="tttgcggtgttttttgattaccaaaaaaaagaTGTGTGCctc ctgttcagttGGAGAACCTAACtccgacaggtgcaatttacgctcctgcatcttaaaa t" /listShort="S483, ykzP, ykzE" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 1417493..1417560 /Source="Nicolas_S_feature" /locus_tag="new_1417493_1417560" /HighExp="S8, S6, S7, S5, ferm, nit, BT, B36, Pyr, G/S" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigGF" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S483" upshifts 1417493 /Source="Nicolas_upshifts" /id="U1094" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=834 /SigmaFactorBS="tttgcggtgttttttgattaccaaaaaaaagaTGTGTGCctc ctgttcagttGGAGAACCTAACtccgacaggtgcaatttacgctcctgcatcttaaaa t" /listShort="S483, ykzP, ykzE" /GFF_Attribute="listLong" CDS 1417561..1417716 /gene="ykzP" /locus_tag="BSU_13509" /old_locus_tag="BSU13509" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="YP_003097718.1" /db_xref="EnsemblGenomes-Gn:BSU13509" /db_xref="EnsemblGenomes-Tr:CAX52609" /db_xref="UniProtKB/Swiss-Prot:C0H402" /translation="MKRKAEVNEAIKNNNTPTESMDPNSYKTQYHDDPNFRGANRNSK QGQQGGM*" gene 1417561..1417716 /gene="ykzP" /locus_tag="BSU_13509" /old_locus_tag="BSU13509" CDS 1417719..1417895 /gene="ykzE" /locus_tag="BSU_13510" /old_locus_tag="BSU13510" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 17322312" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_389234.1" /db_xref="EnsemblGenomes-Gn:BSU13510" /db_xref="EnsemblGenomes-Tr:CAB13224" /db_xref="SubtiList:BG13333" /db_xref="UniProtKB/Swiss-Prot:O31659" /translation="MKKNRHSRDMQNHKKPMNKKVLEEEFSSELGDYNAGKIIETLEV TKPEKKKEKNKKQQ*" gene 1417719..1417895 /gene="ykzE" /locus_tag="BSU_13510" /old_locus_tag="BSU13510" promotor_no_box 1417785..1417885 /Source="Nicolas_upshift_promotors" /id="U1095" /multdbtbs="-" /comp="M21" /sig="Sig-" /pcomp="0.683316683316683" /psig="0.005994005994006" /xcortree=278 /SigmaFactorBS="gaggaagaattctcaagtgaactcggggattacaatgccgga aagatcatcgaaacgctggaagtcaccaagcctgaaaagaaaaaagaaaaaaacaaaa a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_no_box" upshifts 1417845 /Source="Nicolas_upshifts" /id="U1095" /multdbtbs="-" /comp="M21" /sig="Sig-" /pcomp="0.683316683316683" /psig="0.005994005994006" /xcortree=278 /SigmaFactorBS="gaggaagaattctcaagtgaactcggggattacaatgccgga aagatcatcgaaacgctggaagtcaccaagcctgaaaagaaaaaagaaaaaaacaaaa a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" downshifts 1417891 /Source="Nicolas_upshifts" /id="D742" /incds=0 /nref=56 /ntot=112 /MaxReadThrough="2.40289" /MaxDrop="8.38761" /score="26.5107018" /energy="-19.7" /TU="NA" /idTUdmin="U1094" /TUdmin=2 /isTUend="TRUE" CDS complement(1417938..1418960) /gene="ykrP" /locus_tag="BSU_13520" /old_locus_tag="BSU13520" /EC_number="2.3.-.-" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative integral membrane protein; putative acyltransferase" /protein_id="NP_389235.1" /db_xref="EnsemblGenomes-Gn:BSU13520" /db_xref="EnsemblGenomes-Tr:CAB13225" /db_xref="GOA:O31660" /db_xref="InterPro:IPR002656" /db_xref="SubtiList:BG13276" /db_xref="UniProtKB/Swiss-Prot:O31660" /translation="MSKSRDSYFDNAKFLLIFLVVFGHILRSFINDNHFMLYLYKFIY TFHMPAFILVSGYFAKGFKRAGYVKKLAVKLIIPYLIFQIIYSVFYYIMQDESMANVN PIDPQWSLWFLVSLFFWNLLLYPFSKLSKQWALFVSCGIAVLIGYLDFVSSTLSLSRT FVFLPMFLVGFYLNKHHFDLLRSKRGKQIALGVLAAVFVICWGIDFDYSFLFGSKPYS SFGDVTLVSGLSRIGWYVLAFGATFSFLALVPQKRYFFTKWGTRTFYVYLLHGFIIKT LRQVGLEDWLTDYQSLVILLLLTAALTSVLSSNFVKTVAQPFIELRMTSLLQFVRGTG KNAYLK*" gene complement(1417938..1418960) /gene="ykrP" /locus_tag="BSU_13520" /old_locus_tag="BSU13520" downshifts complement(1417961) /Source="Nicolas_upshifts" /id="D743" /incds=0 /nref=11 /ntot=58 /MaxReadThrough="2.29259" /MaxDrop="3.64731" /score="30.4184602" /energy="-16.9" /TU="NA" /idTUdmin="U1096" /TUdmin=92 /isTUend="FALSE" promotor_-10 complement(1419005..1419024) /Source="Nicolas_upshift_promotors" /id="U1096" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.816183816183816" /psig="0.987012987012987" /xcortree=580 /SigmaFactorBS="ccgtcactttacatcgacctaacaatcagcatttttttaGAT TCCTttttcatctttTATTTTAAAATATGTACCAGcagggaataatctcttagtgact g" /listShort="ykrP" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1419021) /Source="Nicolas_upshifts" /id="U1096" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.816183816183816" /psig="0.987012987012987" /xcortree=580 /SigmaFactorBS="ccgtcactttacatcgacctaacaatcagcatttttttaGAT TCCTttttcatctttTATTTTAAAATATGTACCAGcagggaataatctcttagtgact g" /listShort="ykrP" /GFF_Attribute="listLong" promotor_-35 complement(1419036..1419042) /Source="Nicolas_upshift_promotors" /id="U1096" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.816183816183816" /psig="0.987012987012987" /xcortree=580 /SigmaFactorBS="ccgtcactttacatcgacctaacaatcagcatttttttaGAT TCCTttttcatctttTATTTTAAAATATGTACCAGcagggaataatctcttagtgact g" /listShort="ykrP" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1419149..1419157 /Source="Nicolas_upshift_promotors" /id="U1097" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=548 /SigmaFactorBS="gtaatgtaatgacgctgaaattttctgaaatttatagggcaa atGAAGGAAGTtcccgcatttTGTAGAAATATTGAGGGATaggttttgaagaaggagt g" /listShort="kinE, ogt, S485" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 1419165 /Source="Nicolas_upshifts" /id="U1097" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=548 /SigmaFactorBS="gtaatgtaatgacgctgaaattttctgaaatttatagggcaa atGAAGGAAGTtcccgcatttTGTAGAAATATTGAGGGATaggttttgaagaaggagt g" /listShort="kinE, ogt, S485" /GFF_Attribute="listLong" promotor_-10 1419168..1419186 /Source="Nicolas_upshift_promotors" /id="U1097" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=548 /SigmaFactorBS="gtaatgtaatgacgctgaaattttctgaaatttatagggcaa atGAAGGAAGTtcccgcatttTGTAGAAATATTGAGGGATaggttttgaagaaggagt g" /listShort="kinE, ogt, S485" /GFF_Attribute="listLong" /label="promotor_-10" CDS 1419213..1421429 /gene="kinE" /locus_tag="BSU_13530" /old_locus_tag="BSU13530" /function="16.3: Control" /function="16.12: Sense" /experiment="publication(s) with functional evidences, PMID:11069677, 12169614, 16166384, 25701730" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11069677, 12169614, 16166384, 25701730; Product type rc: receptor" /codon_start=1 /transl_table=11 /product="two-component sensor histidine kinase" /protein_id="NP_389236.1" /db_xref="EnsemblGenomes-Gn:BSU13530" /db_xref="EnsemblGenomes-Tr:CAB13226" /db_xref="GOA:O31661" /db_xref="InterPro:IPR000014" /db_xref="InterPro:IPR003594" /db_xref="InterPro:IPR003661" /db_xref="InterPro:IPR004358" /db_xref="InterPro:IPR005467" /db_xref="InterPro:IPR013767" /db_xref="InterPro:IPR035965" /db_xref="InterPro:IPR036097" /db_xref="InterPro:IPR036890" /db_xref="SubtiList:BG13277" /db_xref="UniProtKB/Swiss-Prot:O31661" /translation="METLGVQTNSELREELNRLKEENARLKKELNQHQVIVNNTLDAI FICDNEMRIVQANEATERMLQVDSEDLKKRSVLDFLFSIPKDELNLSVKKFFKKGFLW KEVPIRLDCGATKYIEFLAKRGIGEDFFFVVMRDISSKKILEREFSMNEQLFKDLFDR AVDGIVLFDKDGGFIDANLSFCKSFEINHNELSHLSLYEFIDSGSRKDFDNIWKALNR KGKAKGELPVKLRSGVQKLFEFTITSNIISGFYMSIMRDITEKRSMELQLFKSEERFR EIFENAMDAIIIWSNDGRIVKANQSACKIFELPMNLLLKRKLCDFLVDSQQKYSITKR KYAKYGEIREELLFQMGNGQFKELEFTSKRTILENQHLTILRNVSDRKRMEKELRESE LKFRKVFNGSMDGNVLFDNQYRIIDANPLASHILGLSHEEIKQHSLLDIISAYEIENL ASPARQINFDEMDNEIPFLLSSGDNRKLEFSFKRNIIQNMNLAIFKDVTERKELEERL RKSDTLHVVGELAAGIAHEIRNPMTALKGFIQLLKGSVEGDYALYFNVITSELKRIES IITEFLILAKPQAIMYEEKHVTQIMRDTIDLLNAQANLSNVQMQLDLIDDIPPIYCEP NQLKQVFINILKNAIEVMPDGGNIFVTIKALDQDHVLISLKDEGIGMTEDKLKRLGEP FYTTKERGTGLGLMVSYKIIEEHQGEIMVESEEGKGTVFHITLPVRQNAEERRNDE*" gene 1419213..1421429 /gene="kinE" /locus_tag="BSU_13530" /old_locus_tag="BSU13530" S_feature complement(1421204..1422144) /Source="Nicolas_S_feature" /locus_tag="new_1421204_1422144_c" /HighExp="Pyr, Glucon, C30, Glu, Mal, M/G, G/S, Heat, Fru, B36" /AntisenseName="ogt" /AntisenseCor="-0.33210294457391598" /AntisenseRegPval="-7.6" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="1, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S484" promotor_-35 1421282..1421289 /Source="Nicolas_upshift_promotors" /id="U1098" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.655344655344655" /psig="0.999000999001" /xcortree=2063 /SigmaFactorBS="acttggtgaaccgttttatacgacaaaggaacggggAACTGG ACttgggcttatggtaAGCTATAAAATTATTGAAGAacatcaaggcgagattatggta g" /listShort="ogt, S485" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1421304..1421323 /Source="Nicolas_upshift_promotors" /id="U1098" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.655344655344655" /psig="0.999000999001" /xcortree=2063 /SigmaFactorBS="acttggtgaaccgttttatacgacaaaggaacggggAACTGG ACttgggcttatggtaAGCTATAAAATTATTGAAGAacatcaaggcgagattatggta g" /listShort="ogt, S485" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1421306 /Source="Nicolas_upshifts" /id="U1098" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.655344655344655" /psig="0.999000999001" /xcortree=2063 /SigmaFactorBS="acttggtgaaccgttttatacgacaaaggaacggggAACTGG ACttgggcttatggtaAGCTATAAAATTATTGAAGAacatcaaggcgagattatggta g" /listShort="ogt, S485" /GFF_Attribute="listLong" CDS 1421426..1421923 /gene="ogt" /locus_tag="BSU_13540" /old_locus_tag="BSU13540" /EC_number="2.1.1.63" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:2105461, 2308822, 2359121, 2506524, 7565865" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 2105461, 2308822, 2359121, 2506524, 7565865; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="O6-alkylguanine DNA alkyltransferase" /protein_id="NP_389237.1" /db_xref="EnsemblGenomes-Gn:BSU13540" /db_xref="EnsemblGenomes-Tr:CAB13227" /db_xref="GOA:P11742" /db_xref="InterPro:IPR001497" /db_xref="InterPro:IPR008332" /db_xref="InterPro:IPR014048" /db_xref="InterPro:IPR023546" /db_xref="InterPro:IPR036217" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036631" /db_xref="SubtiList:BG10848" /db_xref="UniProtKB/Swiss-Prot:P11742" /translation="MNYYTTAETPLGELIIAEEEDRITRLFLSQEDWVDWKETVQNTE HKETPNLAEAKQQLQEYFAGERKTFSLPLSQKGTPFQQKVWQALERIPYGESRSYADI AAAVGSPKAVRAVGQANKRNDLPIFVPCHRVIGKNSALTGYAGSKTEIKAFLLNIERI SYKEK*" gene 1421426..1421923 /gene="ogt" /locus_tag="BSU_13540" /old_locus_tag="BSU13540" S_feature 1421924..1422163 /Source="Nicolas_S_feature" /locus_tag="new_1421924_1422163" /HighExp="Lbstat, S2, BT, BC, LPhT, dia15, LBGstat, M0t90, M9-stat, Sw" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.981549" /TUshortSig="SigA, SigH" /TUshortPSig="0.999, 0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S485" CDS 1422013..1422138 /locus_tag="BSU_13545" /old_locus_tag="BSU13545" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_009513954.1" /translation="MKPSRSEKLAVFAELFVKLHILSSAQKDEIINVNKKKQKNR*" gene 1422013..1422138 /locus_tag="BSU_13545" /old_locus_tag="BSU13545" downshifts 1422131 /Source="Nicolas_upshifts" /id="D744" /incds=0 /nref=80 /ntot=239 /MaxReadThrough="1.90528" /MaxDrop="5.2481" /score="4.84132266" /energy="-15.5" /TU="NA" /idTUdmin="U1097" /TUdmin="-4" /isTUend="TRUE" CDS complement(1422172..1423233) /gene="mtnA" /locus_tag="BSU_13550" /old_locus_tag="BSU13550" /EC_number="5.3.1.23" /function="16.8: Protect" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:14551435, 15102328, 16511105, 17690466, 18156470" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 14551435, 15102328, 16511105, 17690466, 18156470; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="methylthioribose-1-phosphate isomerase (methionine salvage pathway)" /protein_id="NP_389238.1" /db_xref="EnsemblGenomes-Gn:BSU13550" /db_xref="EnsemblGenomes-Tr:CAB13228" /db_xref="GOA:O31662" /db_xref="InterPro:IPR000649" /db_xref="InterPro:IPR005251" /db_xref="InterPro:IPR011559" /db_xref="InterPro:IPR027363" /db_xref="PDB:2YRF" /db_xref="PDB:2YVK" /db_xref="SubtiList:BG13278" /db_xref="UniProtKB/Swiss-Prot:O31662" /translation="MTHSFAVPRSVEWKETAITILNQQKLPDETEYLELTTKEDVFDA IVTLKVRGAPAIGITAAFGLALAAKDIETDNVTEFRRRLEDIKQYLNSSRPTAINLSW ALERLSHSVENAISVNEAKTNLVHEAIQIQVEDEETCRLIGQNALQLFKKGDRIMTIC NAGSIATSRYGTALAPFYLAKQKDLGLHIYACETRPVLQGSRLTAWELMQGGIDVTLI TDSMAAHTMKEKQISAVIVGADRIAKNGDTANKIGTYGLAILANAFDIPFFVAAPLST FDTKVKCGADIPIEERDPEEVRQISGVRTAPSNVPVFNPAFDITPHDLISGIITEKGI MTGNYEEEIEQLFKGEKVH*" gene complement(1422172..1423233) /gene="mtnA" /locus_tag="BSU_13550" /old_locus_tag="BSU13550" downshifts complement(1422189) /Source="Nicolas_upshifts" /id="D745" /incds=0 /nref=261 /ntot=286 /MaxReadThrough="4.47312" /MaxDrop="7.97339" /score="34.04363" /energy="-17.1" /TU="U1099,U1102" /idTUdmin="U1102" /TUdmin="-418" /isTUend="FALSE" CDS complement(1423241..1424434) /gene="mtnK" /locus_tag="BSU_13560" /old_locus_tag="BSU13560" /EC_number="2.7.1.100" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:210167, 11545674, 15102328, 17522047, 23649237" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 210167, 11545674, 15102328, 17522047, 23649237; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="methylthioribose kinase (methionine salvage pathway, promiscuous)" /protein_id="NP_389239.2" /db_xref="EnsemblGenomes-Gn:BSU13560" /db_xref="EnsemblGenomes-Tr:CAB13229" /db_xref="GOA:O31663" /db_xref="InterPro:IPR002575" /db_xref="InterPro:IPR009212" /db_xref="InterPro:IPR011009" /db_xref="PDB:2OLC" /db_xref="PDB:2PU8" /db_xref="PDB:2PUI" /db_xref="PDB:2PUL" /db_xref="PDB:2PUN" /db_xref="PDB:2PUP" /db_xref="SubtiList:BG13279" /db_xref="UniProtKB/Swiss-Prot:O31663" /translation="MGVTKTPLYETLNESSAVALAVKLGLFPSKSTLTCQEIGDGNLN YVFHIYDQEHDRALIIKQAVPYAKVVGESWPLTIDRARIESSALIRQGEHVPHLVPRV FYSDTEMAVTVMEDLSHLKIARKGLIEGENYPHLSQHIGEFLGKTLFYSSDYALEPKV KKQLVKQFTNPELCDITERLVFTDPFFDHDTNDFEEELRPFVEKLWNNDSVKIEAAKL KKSFLTSAETLIHGDLHTGSIFASEHETKVIDPEFAFYGPIGFDVGQFIANLFLNALS RDGADREPLYEHVNQVWETFEETFSEAWQKDSLDVYANIDGYLTDTLSHIFEEAIGFA GCELIRRTIGLAHVADLDTIVPFDKRIGRKRLALETGTAFIEKRSEFKTITDVIELFK LLVKE*" gene complement(1423241..1424434) /gene="mtnK" /locus_tag="BSU_13560" /old_locus_tag="BSU13560" downshifts 1423301 /Source="Nicolas_upshifts" /id="D746" /incds=1 /nref=1 /ntot=51 /MaxReadThrough="3.02938" /MaxDrop="3.49719" /score="4.84132266" /energy="-15.5" /TU="NA" /idTUdmin="U1097" /TUdmin=1166 /isTUend="FALSE" downshifts complement(1424521) /Source="Nicolas_upshifts" /id="D747" /incds=0 /nref=1 /ntot=1 /MaxReadThrough="8.61071" /MaxDrop="3.05641" /score="27.7981655" /energy="-17.6" /TU="U1099,U1102" /idTUdmin="U1102" /TUdmin="-2750" /isTUend="FALSE" misc_RNA complement(1424527..1424683) /gene="mswC" /locus_tag="BSU_misc_RNA_20" /product="S-adenosylmethionine riboswitch" /experiment="publication(s) with functional evidences, PMID:10094622, 12626738, 12910260, 15102328, 17381305, 18039762" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10094622, 12626738, 12910260, 15102328, 17381305, 18039762; Product type n : RNA" /function="12: Regulatory functions" gene complement(1424527..1424683) /gene="mswC" /locus_tag="BSU_misc_RNA_20" promotor_-10 complement(1424718..1424737) /Source="Nicolas_upshift_promotors" /id="U1099" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.971028971028971" /psig=1 /xcortree=2894 /SigmaFactorBS="agatttatattaaaaaataTATTGACAactaactaaattacc TGTTACCATGTTCATCAACTgataaattagaattgtcaaacaagtgaatatattctct t" /listShort="NA, mtnK, mtnA, S484" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1424719) /Source="Nicolas_upshifts" /id="U1099" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.971028971028971" /psig=1 /xcortree=2894 /SigmaFactorBS="agatttatattaaaaaataTATTGACAactaactaaattacc TGTTACCATGTTCATCAACTgataaattagaattgtcaaacaagtgaatatattctct t" /listShort="NA, mtnK, mtnA, S484" /GFF_Attribute="listLong" promotor_-35 complement(1424753..1424760) /Source="Nicolas_upshift_promotors" /id="U1099" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.971028971028971" /psig=1 /xcortree=2894 /SigmaFactorBS="agatttatattaaaaaataTATTGACAactaactaaattacc TGTTACCATGTTCATCAACTgataaattagaattgtcaaacaagtgaatatattctct t" /listShort="NA, mtnK, mtnA, S484" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1424763..1424766 /Source="Nicolas_upshift_promotors" /id="U1100" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.276723276723277" /psig="0.98001998001998" /xcortree=2865 /SigmaFactorBS="ggtaacaggtaatttagttagttgtcaatataTTTTttaata taaatctttTCTGATATCATCGAAAACAGgaatgctctcccgaacttctgcgctttct t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(1424767..1425546) /gene="mtnU" /locus_tag="BSU_13570" /old_locus_tag="BSU13570" /EC_number="3.5.1.3" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 12022921, 19464248, 19596042, 21288482, 23944997, 24387040; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="ketoglutaramate omega-amidase" /protein_id="NP_389240.1" /db_xref="EnsemblGenomes-Gn:BSU13570" /db_xref="EnsemblGenomes-Tr:CAB13230" /db_xref="GOA:O31664" /db_xref="InterPro:IPR003010" /db_xref="InterPro:IPR036526" /db_xref="SubtiList:BG13280" /db_xref="UniProtKB/Swiss-Prot:O31664" /translation="MKWTISCLQFDISYGKPSENIKKAEFFIEKESKHADVLVLPELW TTGYDLANLDELADEDGRSAQSWLKKTAKKHGVHIVAGSVAVRKNSDVYNTMYIADKE GQIIKEYRKAHLFQLMDEHLYLSAGSEDGYFELDGVKSSGLICYDIRFPEWIRKHTTK GANVLFISAEWPLPRLDHWKSLLIARAIENQCFVAACNCTGSNPDNEFAGHSLIIDPW GRVLAEGGREEGIVRAEIDLQESAEVRESIPVFDDIRKDLY*" gene complement(1424767..1425546) /gene="mtnU" /locus_tag="BSU_13570" /old_locus_tag="BSU13570" promotor_-10 1424782..1424801 /Source="Nicolas_upshift_promotors" /id="U1100" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.276723276723277" /psig="0.98001998001998" /xcortree=2865 /SigmaFactorBS="ggtaacaggtaatttagttagttgtcaatataTTTTttaata taaatctttTCTGATATCATCGAAAACAGgaatgctctcccgaacttctgcgctttct t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1424791 /Source="Nicolas_upshifts" /id="U1100" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.276723276723277" /psig="0.98001998001998" /xcortree=2865 /SigmaFactorBS="ggtaacaggtaatttagttagttgtcaatataTTTTttaata taaatctttTCTGATATCATCGAAAACAGgaatgctctcccgaacttctgcgctttct t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 1425239..1425246 /Source="Nicolas_upshift_promotors" /id="U1101" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.634365634365634" /psig="0.99100899100899" /xcortree=2893 /SigmaFactorBS="ttttctgtactctttaatgatttgcCCTTCCTTatccgcgat gtaCATTGTATTATAAACATCAGaattcttcctgacagcgaccgatccggcgacaata t" /listShort="S486, mtnE" /listLong="NA, mtnW, mtnX, mtnB, mtnD" /label="promotor_-35" promotor_-10 1425259..1425278 /Source="Nicolas_upshift_promotors" /id="U1101" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.634365634365634" /psig="0.99100899100899" /xcortree=2893 /SigmaFactorBS="ttttctgtactctttaatgatttgcCCTTCCTTatccgcgat gtaCATTGTATTATAAACATCAGaattcttcctgacagcgaccgatccggcgacaata t" /listShort="S486, mtnE" /listLong="NA, mtnW, mtnX, mtnB, mtnD" /label="promotor_-10" upshifts 1425274 /Source="Nicolas_upshifts" /id="U1101" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.634365634365634" /psig="0.99100899100899" /xcortree=2893 /SigmaFactorBS="ttttctgtactctttaatgatttgcCCTTCCTTatccgcgat gtaCATTGTATTATAAACATCAGaattcttcctgacagcgaccgatccggcgacaata t" /listShort="S486, mtnE" /listLong="NA, mtnW, mtnX, mtnB, mtnD" S_feature 1425281..1425598 /Source="Nicolas_S_feature" /locus_tag="new_1425281_1425598" /HighExp="LoTm, S8, C30, BC, S7, B36, B60, T2.0H, Sw, UNK1" /AntisenseName="mtnU" /AntisenseCor="0.77659263363209297" /AntisenseRegPval="-54.8" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.991" /TUlongSig="NA" /TUlongPSig="NA" /label="S486" promotor_-35 1425568..1425575 /Source="Nicolas_upshift_promotors" /id="U1103" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.929070929070929" /psig=1 /xcortree=3072 /SigmaFactorBS="atttcatctttttaacaccccaaattttTCTTTACTtttttc atttaaccATATATGATGATGGACTATCatttcaagatttttttagaaggtgagaata g" /listShort="mtnE, NA, mtnW, mtnX, mtnB, mtnD" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(1425576..1425595) /Source="Nicolas_upshift_promotors" /id="U1102" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.827172827172827" /psig=1 /xcortree=2895 /SigmaFactorBS="caaatttcatctattctcaccttctaaaaaaaTCTTGAAAtg atagtccatcatcATATATGGTTAAATGAAAAAagtaaagaaaaatttggggtgttaa a" /listShort="mtnU, NA, mtnK, mtnA, S484" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-10 1425590..1425609 /Source="Nicolas_upshift_promotors" /id="U1103" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.929070929070929" /psig=1 /xcortree=3072 /SigmaFactorBS="atttcatctttttaacaccccaaattttTCTTTACTtttttc atttaaccATATATGATGATGGACTATCatttcaagatttttttagaaggtgagaata g" /listShort="mtnE, NA, mtnW, mtnX, mtnB, mtnD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1425590) /Source="Nicolas_upshifts" /id="U1102" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.827172827172827" /psig=1 /xcortree=2895 /SigmaFactorBS="caaatttcatctattctcaccttctaaaaaaaTCTTGAAAtg atagtccatcatcATATATGGTTAAATGAAAAAagtaaagaaaaatttggggtgttaa a" /listShort="mtnU, NA, mtnK, mtnA, S484" /GFF_Attribute="listLong" upshifts 1425600 /Source="Nicolas_upshifts" /id="U1103" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.929070929070929" /psig=1 /xcortree=3072 /SigmaFactorBS="atttcatctttttaacaccccaaattttTCTTTACTtttttc atttaaccATATATGATGATGGACTATCatttcaagatttttttagaaggtgagaata g" /listShort="mtnE, NA, mtnW, mtnX, mtnB, mtnD" /GFF_Attribute="listLong" promotor_-35 complement(1425611..1425618) /Source="Nicolas_upshift_promotors" /id="U1102" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.827172827172827" /psig=1 /xcortree=2895 /SigmaFactorBS="caaatttcatctattctcaccttctaaaaaaaTCTTGAAAtg atagtccatcatcATATATGGTTAAATGAAAAAagtaaagaaaaatttggggtgttaa a" /listShort="mtnU, NA, mtnK, mtnA, S484" /GFF_Attribute="listLong" /label="promotor_-35" CDS 1425641..1426837 /gene="mtnE" /locus_tag="BSU_13580" /old_locus_tag="BSU13580" /EC_number="2.6.1.1" /function="16.2: Construct biomass (Anabolism)" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:12670965, 15102328, 23429746, 24387040" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12670965, 15102328, 23429746, 24387040; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="methionine-glutamine aminotransferase" /protein_id="NP_389241.1" /db_xref="EnsemblGenomes-Gn:BSU13580" /db_xref="EnsemblGenomes-Tr:CAB13231" /db_xref="GOA:O31665" /db_xref="InterPro:IPR004839" /db_xref="InterPro:IPR015421" /db_xref="InterPro:IPR015422" /db_xref="InterPro:IPR015424" /db_xref="SubtiList:BG13281" /db_xref="UniProtKB/Swiss-Prot:O31665" /translation="MKFEQSHVLKELPKQFFASLVQKVNRKLAEGHDVINLGQGNPDQ PTPEHIVEEMKRAVADPENHKYSSFRGSYRLKSAAAAFYKREYGIDLDPETEVAVLFG GKAGLVELPQCLLNPGDTILVPDPGYPDYWSGVTLAKAKMEMMPLVKDRAFLPDYSSI TAEIREQAKLMYLNYPNNPTGAVATSEFFEDTVRFAAENGICVVHDFAYGAVGFDGCK PLSFLQTEGAKDIGIEIYTLSKTYNMAGWRVGFAVGNASVIEAINLYQDHMFVSLFRA TQEAAAEALLADQTCVAEQNARYESRRNAWITACREIGWDVTAPAGSFFAWLPVPEGY TSEQFSDLLLEKANVAVAAGNGFGEYGEGYVRVGLLTSEERLKEAAYRIGKLNLFTQK SIDKTL*" gene 1425641..1426837 /gene="mtnE" /locus_tag="BSU_13580" /old_locus_tag="BSU13580" promotor_-35 1426819..1426826 /Source="Nicolas_upshift_promotors" /id="U1104" /multdbtbs="SigA,SigA" /comp="M14" /sig="SigA" /pcomp="0.954045954045954" /psig="0.998001998001998" /xcortree=2896 /SigmaFactorBS="acctgtttacccaaaaaagCATTGACAagaccttataacgaT GGGATAATTCAAAATAATTtataaaatctatattttcttatcaagagcaggcagaggg a" /listShort="NA, mtnW, mtnX, mtnB, mtnD" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1426841..1426860 /Source="Nicolas_upshift_promotors" /id="U1104" /multdbtbs="SigA,SigA" /comp="M14" /sig="SigA" /pcomp="0.954045954045954" /psig="0.998001998001998" /xcortree=2896 /SigmaFactorBS="acctgtttacccaaaaaagCATTGACAagaccttataacgaT GGGATAATTCAAAATAATTtataaaatctatattttcttatcaagagcaggcagaggg a" /listShort="NA, mtnW, mtnX, mtnB, mtnD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1426860 /Source="Nicolas_upshifts" /id="U1104" /multdbtbs="SigA,SigA" /comp="M14" /sig="SigA" /pcomp="0.954045954045954" /psig="0.998001998001998" /xcortree=2896 /SigmaFactorBS="acctgtttacccaaaaaagCATTGACAagaccttataacgaT GGGATAATTCAAAATAATTtataaaatctatattttcttatcaagagcaggcagaggg a" /listShort="NA, mtnW, mtnX, mtnB, mtnD" /GFF_Attribute="listLong" misc_RNA 1426876..1426976 /gene="mswD" /locus_tag="BSU_misc_RNA_21" /product="S-adenosylmethionine riboswitch" /experiment="publication(s) with functional evidences, PMID:10094622, 12626738, 12910260, 15102328, 17381305, 18039762" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10094622, 12626738, 12910260, 15102328, 17381305, 18039762; Product type n : RNA" /function="16.3: Control" gene 1426876..1426976 /gene="mswD" /locus_tag="BSU_misc_RNA_21" downshifts 1426975 /Source="Nicolas_upshifts" /id="D748" /incds=0 /nref=49 /ntot=190 /MaxReadThrough="7.27369" /MaxDrop="4.19981" /score="-1.80590532" /energy="-10.7" /TU="U1103,U1104" /idTUdmin="U1101" /TUdmin=110 /isTUend="FALSE" CDS 1427061..1428278 /gene="mtnW" /locus_tag="BSU_13590" /old_locus_tag="BSU13590" /EC_number="5.3.2.5" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:12022921, 14551435, 15102328, 15950120, 16737967, 18403380" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12022921, 14551435, 15102328, 15950120, 16737967, 18403380; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="2,3-diketo-5-methylthiopentyl-1-phosphate enolase (DK-MTP-1-P enolase)" /protein_id="NP_389242.2" /db_xref="EnsemblGenomes-Gn:BSU13590" /db_xref="EnsemblGenomes-Tr:CAB13232" /db_xref="GOA:O31666" /db_xref="InterPro:IPR000685" /db_xref="InterPro:IPR017443" /db_xref="InterPro:IPR017717" /db_xref="InterPro:IPR033966" /db_xref="InterPro:IPR036376" /db_xref="InterPro:IPR036422" /db_xref="PDB:2ZVI" /db_xref="SubtiList:BG13282" /db_xref="UniProtKB/Swiss-Prot:O31666" /translation="MSELLATYLLTEPGADTEKKAEQIATGLTVGSWTDLPLVKQEQM QKHKGRVIKVEEREGTAASEKQAVITIAYPEINFSQDIPALLTTVFGKLSLDGKIKLI DLHFSEAFKRALPGPKFGVYGIRKLLGEFERPLLMSIFKGVIGRDLSDIKEQLRQQAL GGVDLIKDDEIFFETGLAPFETRIAEGKQILKETYEQTGHKTLYAVNLTGRTADLKDK ARRAAELGADALLFNVFAYGLDVMQGLAEDPEIPVPIMAHPAVSGAFTSSPFYGFSHA LLLGKLNRYCGADFSLFPSPYGSVALPRADALAIHEECVREDAFNQTFAVPSAGIHPG MVPLLMRDFGIDHIINAGGGVHGHPNGAQGGGRAFRAIIDAVLEAQPIDEKAEQCKDL KLALDKWGKAEAV*" gene 1427061..1428278 /gene="mtnW" /locus_tag="BSU_13590" /old_locus_tag="BSU13590" CDS 1428275..1428982 /gene="mtnX" /locus_tag="BSU_13600" /old_locus_tag="BSU13600" /EC_number="3.1.3.87" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:12022921, 14551435, 15102328, 15950120, 17654724" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12022921, 14551435, 15102328, 15950120, 17654724; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="2-hydroxy-3-keto-5-methylthiopentenyl-1- phosphatephosphatase (HK-MTPenyl-1-P phosphatase)" /protein_id="NP_389243.1" /db_xref="EnsemblGenomes-Gn:BSU13600" /db_xref="EnsemblGenomes-Tr:CAB13233" /db_xref="GOA:O31667" /db_xref="InterPro:IPR006384" /db_xref="InterPro:IPR017718" /db_xref="InterPro:IPR023214" /db_xref="InterPro:IPR036412" /db_xref="PDB:2FEA" /db_xref="SubtiList:BG13283" /db_xref="UniProtKB/Swiss-Prot:O31667" /translation="MTTRKPFIICDFDGTITMNDNIINIMKTFAPPEWMALKDGVLSK TLSIKEGVGRMFGLLPSSLKEEITSFVLEDAKIREGFREFVAFINEHEIPFYVISGGM DFFVYPLLEGIVEKDRIYCNHASFDNDYIHIDWPHSCKGTCSNQCGCCKPSVIHELSE PNQYIIMIGDSVTDVEAAKLSDLCFARDYLLNECREQNLNHLPYQDFYEIRKEIENVK EVQEWLQNKNAGESSLK*" gene 1428275..1428982 /gene="mtnX" /locus_tag="BSU_13600" /old_locus_tag="BSU13600" CDS 1428940..1429569 /gene="mtnB" /locus_tag="BSU_13610" /old_locus_tag="BSU13610" /EC_number="4.2.1.109" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:12022921, 14551435, 15102328, 18391471, 23285211" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12022921, 14551435, 15102328, 18391471, 23285211; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase)" /protein_id="NP_389244.1" /db_xref="EnsemblGenomes-Gn:BSU13610" /db_xref="EnsemblGenomes-Tr:CAB13234" /db_xref="GOA:O31668" /db_xref="InterPro:IPR001303" /db_xref="InterPro:IPR017714" /db_xref="InterPro:IPR036409" /db_xref="SubtiList:BG13284" /db_xref="UniProtKB/Swiss-Prot:O31668" /translation="MAAKQERWRELAEVKRELAERDWFPATSGNLSIKVTDEPLTFLV TASGKDKRKETVEDFLLVDQNGEPAESGHSLKPSAETLLHTHLYNKTNAGCCLHVHTV NNNVISELYGDQKKITFKGQEIIKALGLWEENAEVTVPIIENPAHIPTLAALFAEEIS EDSGAVLIRNHGITAWGKTAFEAKRVLEAYEFLFSYHLKLKTLEHQLVK*" gene 1428940..1429569 /gene="mtnB" /locus_tag="BSU_13610" /old_locus_tag="BSU13610" CDS 1429584..1430120 /gene="mtnD" /locus_tag="BSU_13620" /old_locus_tag="BSU13620" /EC_number="1.13.11.54" /EC_number="1.13.11.53" /function="16.11: Scavenge (Catabolism)" /function="16.8: Protect" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:10704478, 11371200, 12022880, 12022921, 12402029, 15102328, 16297065, 16783794, 24036122" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10704478, 11371200, 12022880, 12022921, 12402029, 15102328, 16297065, 16783794, 24036122; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="acireductone dioxygenase (Ni2+ or Fe2+-requiring)" /protein_id="NP_389245.1" /db_xref="EnsemblGenomes-Gn:BSU13620" /db_xref="EnsemblGenomes-Tr:CAB13235" /db_xref="GOA:O31669" /db_xref="InterPro:IPR004313" /db_xref="InterPro:IPR011051" /db_xref="InterPro:IPR014710" /db_xref="InterPro:IPR023956" /db_xref="SubtiList:BG13285" /db_xref="UniProtKB/Swiss-Prot:O31669" /translation="MATIRIHDEANTTIENQEEVASFLDSQEVIYEQWDITRLPEHLS EKYDLTEEEKQQILDTFETEIKDISTRRGYKAQDVISLSDSNPKLDELLENFKREHHH TDDEVRFIVSGHGIFVIQGQDGTFFDVRLNPGDLISVPENIRHYFTLQEDRKVVAVRI FVTTEGWVPIYEKDSVNQ*" gene 1429584..1430120 /gene="mtnD" /locus_tag="BSU_13620" /old_locus_tag="BSU13620" S_feature complement(1429967..1430160) /Source="Nicolas_S_feature" /locus_tag="new_1429967_1430160_c" /HighExp="Lbstat, Cold, LBGstat, T0.30H, M9-stat, B60, ferm, T1.30H, LPhT, M0t90" /AntisenseName="mtnD" /AntisenseCor="-0.31139057410816301" /AntisenseRegPval="-6.7" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S487" downshifts 1430120 /Source="Nicolas_upshifts" /id="D749" /incds=0 /nref=179 /ntot=227 /MaxReadThrough="1.58976" /MaxDrop="6.10661" /score="35.4563733" /energy="-14.9" /TU="NA" /idTUdmin="U1103" /TUdmin="-1" /isTUend="TRUE" CDS complement(1430161..1430481) /gene="ykvA" /locus_tag="BSU_13630" /old_locus_tag="BSU13630" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_389246.1" /db_xref="EnsemblGenomes-Gn:BSU13630" /db_xref="EnsemblGenomes-Tr:CAB13236" /db_xref="GOA:O31670" /db_xref="InterPro:IPR010652" /db_xref="SubtiList:BG13308" /db_xref="UniProtKB/Swiss-Prot:O31670" /translation="MKKKKAIMLGAAGGKAILKRKNRKKCIQHITTFFQMLRDWRNGD YPRSQVKTLLLLTAAILYIVMPLDIIPDVILGLGFIDDAAVLGLIWTLIKKELSQYEK WRLQ*" gene complement(1430161..1430481) /gene="ykvA" /locus_tag="BSU_13630" /old_locus_tag="BSU13630" downshifts complement(1430219) /Source="Nicolas_upshifts" /id="D750" /incds=0 /nref=5 /ntot=148 /MaxReadThrough="4.05831" /MaxDrop="2.74575" /score="18.5455371" /energy="-11.3" /TU="U1106" /idTUdmin="U1106" /TUdmin="-220" /isTUend="FALSE" S_feature complement(1430482..1430571) /Source="Nicolas_S_feature" /locus_tag="new_1430482_1430571_c" /HighExp="Lbstat, M9-stat, B60, T0.30H, LBGstat, M0t90, T1.0H, S2, T3.0H, T3.30H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S488" promotor_-35 1430507..1430513 /Source="Nicolas_upshift_promotors" /id="U1105" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=237 /SigmaFactorBS="tcattgggcatacctcctgcctggcggcgTGTTTAAgatatt cttcacctGGGTATTGTTCTTCTAATCctatcaatatatctattatacctgaaaaatt a" /listShort="S489, S490, spo0E, eag" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1430528..1430546 /Source="Nicolas_upshift_promotors" /id="U1105" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=237 /SigmaFactorBS="tcattgggcatacctcctgcctggcggcgTGTTTAAgatatt cttcacctGGGTATTGTTCTTCTAATCctatcaatatatctattatacctgaaaaatt a" /listShort="S489, S490, spo0E, eag" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1430538 /Source="Nicolas_upshifts" /id="U1105" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=237 /SigmaFactorBS="tcattgggcatacctcctgcctggcggcgTGTTTAAgatatt cttcacctGGGTATTGTTCTTCTAATCctatcaatatatctattatacctgaaaaatt a" /listShort="S489, S490, spo0E, eag" /GFF_Attribute="listLong" S_feature 1430539..1430623 /Source="Nicolas_S_feature" /locus_tag="new_1430539_1430623" /HighExp="Etha, Gly, BC, Salt, Sw, B60, LoTm, M9-stat, LPhT, HiTm" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigB" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S489" promotor_-10 complement(1430553..1430572) /Source="Nicolas_upshift_promotors" /id="U1106" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.682317682317682" /psig="0.999000999001" /xcortree=1602 /SigmaFactorBS="tgcattattacagattatactttatttgtaaacatattttCA TTaaataagttaatttTTCAGGTATAATAGATATATtgataggattagaagaacaata c" /listShort="S488, ykvA, S487" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1430570) /Source="Nicolas_upshifts" /id="U1106" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.682317682317682" /psig="0.999000999001" /xcortree=1602 /SigmaFactorBS="tgcattattacagattatactttatttgtaaacatattttCA TTaaataagttaatttTTCAGGTATAATAGATATATtgataggattagaagaacaata c" /listShort="S488, ykvA, S487" /GFF_Attribute="listLong" promotor_-35 complement(1430587..1430590) /Source="Nicolas_upshift_promotors" /id="U1106" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.682317682317682" /psig="0.999000999001" /xcortree=1602 /SigmaFactorBS="tgcattattacagattatactttatttgtaaacatattttCA TTaaataagttaatttTTCAGGTATAATAGATATATtgataggattagaagaacaata c" /listShort="S488, ykvA, S487" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1430597..1430604 /Source="Nicolas_upshift_promotors" /id="U1107" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.988011988011988" /psig=1 /xcortree=2934 /SigmaFactorBS="tacctgaaaaattaacttatttaatgaaaataTGTTTACAaa taaagtataatcTGTAATAATGCACAATAACCcaatcaaacttgtttcctatttctta g" /listShort="S490, spo0E, eag" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1430619..1430638 /Source="Nicolas_upshift_promotors" /id="U1107" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.988011988011988" /psig=1 /xcortree=2934 /SigmaFactorBS="tacctgaaaaattaacttatttaatgaaaataTGTTTACAaa taaagtataatcTGTAATAATGCACAATAACCcaatcaaacttgtttcctatttctta g" /listShort="S490, spo0E, eag" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 1430625..1430683 /Source="Nicolas_S_feature" /locus_tag="new_1430625_1430683" /HighExp="Etha, Gly, Sw, BC, LoTm, B36, T3.30H, Salt, T5.0H, B60" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigB" /TUshortPSig="1, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S490" upshifts 1430625 /Source="Nicolas_upshifts" /id="U1107" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.988011988011988" /psig=1 /xcortree=2934 /SigmaFactorBS="tacctgaaaaattaacttatttaatgaaaataTGTTTACAaa taaagtataatcTGTAATAATGCACAATAACCcaatcaaacttgtttcctatttctta g" /listShort="S490, spo0E, eag" /GFF_Attribute="listLong" downshifts complement(1430681) /Source="Nicolas_upshifts" /id="D751" /incds=0 /nref=3 /ntot=61 /MaxReadThrough="0.87927" /MaxDrop="3.53961" /score="18.5455371" /energy="-11.3" /TU="NA" /idTUdmin="U1106" /TUdmin="-682" /isTUend="FALSE" CDS 1430684..1430941 /gene="spo0E" /locus_tag="BSU_13640" /old_locus_tag="BSU13640" /function="16.13: Shape" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:15057450, 15916600, 17001075, 19332814, 22524514" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15057450, 15916600, 17001075, 19332814, 22524514; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="negative regulatory phosphatase acting on Spo0A-P (sporulation)" /protein_id="NP_389247.1" /db_xref="EnsemblGenomes-Gn:BSU13640" /db_xref="EnsemblGenomes-Tr:CAB13237" /db_xref="GOA:P05043" /db_xref="InterPro:IPR018540" /db_xref="InterPro:IPR037208" /db_xref="SubtiList:BG10769" /db_xref="UniProtKB/Swiss-Prot:P05043" /translation="MGGSSEQERLLVSIDEKRKLMIDAARKQGFTGHDTIRHSQELDC LINEYHQLMQENEHSQGIQGLVKKLGLWPRRDVMPAYDANK*" gene 1430684..1430941 /gene="spo0E" /locus_tag="BSU_13640" /old_locus_tag="BSU13640" downshifts 1430935 /Source="Nicolas_upshifts" /id="D752" /incds=0 /nref=7 /ntot=169 /MaxReadThrough="4.39402" /MaxDrop="3.59614" /score="0.224700481" /energy="-5.9" /TU="U1105,U1107" /idTUdmin="U1105" /TUdmin="-440" /isTUend="FALSE" CDS 1431027..1431458 /gene="eag" /locus_tag="BSU_13650" /old_locus_tag="BSU13650" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative small membrane protein" /protein_id="NP_389248.1" /db_xref="EnsemblGenomes-Gn:BSU13650" /db_xref="EnsemblGenomes-Tr:CAB13238" /db_xref="GOA:P06630" /db_xref="SubtiList:BG10770" /db_xref="UniProtKB/Swiss-Prot:P06630" /translation="MKELAILITEMVNQFHDAFISLCGIFGIHLTDKEMHFWVIGIFG IFFFGVTHAVFTWLSKWSMTALSFIYTVTVIIVIVFAIEIQQKVTGRGNMEFLDATEG IKGFLVFFMFFLLLKMLLRFIKILFSGRPASKSNGNARSRR*" gene 1431027..1431458 /gene="eag" /locus_tag="BSU_13650" /old_locus_tag="BSU13650" CDS complement(1431486..1433006) /gene="kinD" /locus_tag="BSU_13660" /old_locus_tag="BSU13660" /EC_number="2.7.13.3" /function="16.13: Shape" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:11069677, 11673427, 16166384, 10411754, 21622736, 22074846, 22716461, 23569226" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11069677, 11673427, 16166384, 10411754, 21622736, 22074846, 22716461, 23569226; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="histidine kinase phosphorylating Spo0A" /protein_id="NP_389249.1" /db_xref="EnsemblGenomes-Gn:BSU13660" /db_xref="EnsemblGenomes-Tr:CAB13239" /db_xref="GOA:O31671" /db_xref="InterPro:IPR003594" /db_xref="InterPro:IPR003661" /db_xref="InterPro:IPR004358" /db_xref="InterPro:IPR005467" /db_xref="InterPro:IPR029151" /db_xref="InterPro:IPR033479" /db_xref="InterPro:IPR036097" /db_xref="InterPro:IPR036890" /db_xref="PDB:4JGO" /db_xref="PDB:4JGP" /db_xref="PDB:4JGQ" /db_xref="PDB:4JGR" /db_xref="SubtiList:BG13309" /db_xref="UniProtKB/Swiss-Prot:O31671" /translation="MLERCKLKILKGACGRVKLYIILVVIPAIVISFFVYEKEKDTIA AEHKQEASVLLNLHRNKINYLIGETMARMTSLSIAIDRPVDIKKMQSILEKTFDSEPR FSGLYFLNAKGDVTASTTELKTKVNLADRSFFIKAKETKKTVISDSYSSRITGQPIFT ICVPVLDSKRNVTDYLVAAIQIDYLKNLINLLSPDVYIEVVNQDGKMIFASGQASHAE DQKPVSGYLDDISWNMKVYPNPVTIEELSKSLVLPLSCIIVLLNILFILVLYYLLKRQ TQLERSENEAQKLELIGTLAASTAHEIRNPLTGISGFIQLLQKKYKGEEDQLYFSIIE QEIKRINQIVSEFLVLGKPTAEKWELNSLQDIIGEIMPIIYSEGNLYNVEVELQYLTE QPLLVKCTKDHIKQVILNVAKNGLESMPEGGKLTISLGALDKKAIIKVVDNGEGISQE MLDHIFLPFVTSKEKGTGLGLVVCKRIVLMYGGSIHIESEVRRGTEVTITLPVSAS*" gene complement(1431486..1433006) /gene="kinD" /locus_tag="BSU_13660" /old_locus_tag="BSU13660" downshifts complement(1431498) /Source="Nicolas_upshifts" /id="D753" /incds=0 /nref=106 /ntot=227 /MaxReadThrough="0.62895" /MaxDrop="5.24795" /score="18.5455371" /energy="-11.3" /TU="NA" /idTUdmin="U1109" /TUdmin="-3" /isTUend="TRUE" promotor_-35 1432207..1432213 /Source="Nicolas_upshift_promotors" /id="U1108" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=948 /SigmaFactorBS="ctgggtctgccgcttcagcaaataatacagcacgAGAATAAa aaggatattcagCAGAACAATAATacatgaaagcggaagcacaaggcttttcgacagt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1432227..1432238 /Source="Nicolas_upshift_promotors" /id="U1108" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=948 /SigmaFactorBS="ctgggtctgccgcttcagcaaataatacagcacgAGAATAAa aaggatattcagCAGAACAATAATacatgaaagcggaagcacaaggcttttcgacagt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1432233 /Source="Nicolas_upshifts" /id="U1108" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=948 /SigmaFactorBS="ctgggtctgccgcttcagcaaataatacagcacgAGAATAAa aaggatattcagCAGAACAATAATacatgaaagcggaagcacaaggcttttcgacagt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" misc_feature complement(1433014..1433033) /Source="Nicolas_upshift_promotors" /id="U1109" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.98101898101898" /psig=1 /xcortree=2145 /SigmaFactorBS="aagcttgccaacatctttttctaatttttttggttatttttt cttattaaagaagaagaaacAATGATATAATACCTCTAATcaggtgtatgttggagcg a" /listShort="kinD" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(1433035) /Source="Nicolas_upshifts" /id="U1109" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.98101898101898" /psig=1 /xcortree=2145 /SigmaFactorBS="aagcttgccaacatctttttctaatttttttggttatttttt cttattaaagaagaagaaacAATGATATAATACCTCTAATcaggtgtatgttggagcg a" /listShort="kinD" /GFF_Attribute="listLong" promotor_-35 1433133..1433140 /Source="Nicolas_upshift_promotors" /id="U1110" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.971028971028971" /psig=1 /xcortree=2454 /SigmaFactorBS="cattttaaaaaagaagagaaatattggaaagattttTATTGA CAttttggtctttgttTATTAATGTTTCTCTGTAACggtttctaaaaggatgattgag a" /listShort="mhqR" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1433155..1433174 /Source="Nicolas_upshift_promotors" /id="U1110" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.971028971028971" /psig=1 /xcortree=2454 /SigmaFactorBS="cattttaaaaaagaagagaaatattggaaagattttTATTGA CAttttggtctttgttTATTAATGTTTCTCTGTAACggtttctaaaaggatgattgag a" /listShort="mhqR" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1433157 /Source="Nicolas_upshifts" /id="U1110" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.971028971028971" /psig=1 /xcortree=2454 /SigmaFactorBS="cattttaaaaaagaagagaaatattggaaagattttTATTGA CAttttggtctttgttTATTAATGTTTCTCTGTAACggtttctaaaaggatgattgag a" /listShort="mhqR" /GFF_Attribute="listLong" CDS 1433199..1433636 /gene="mhqR" /locus_tag="BSU_13670" /old_locus_tag="BSU13670" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:17725564, 17962296, 18282125" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 17725564, 17962296, 18282125; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator (MarR family)" /protein_id="NP_389250.1" /db_xref="EnsemblGenomes-Gn:BSU13670" /db_xref="EnsemblGenomes-Tr:CAB13240" /db_xref="GOA:O31672" /db_xref="InterPro:IPR000835" /db_xref="InterPro:IPR023187" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG13310" /db_xref="UniProtKB/Swiss-Prot:O31672" /translation="MTEKSLKLFIVLSRAYRSINDHMNKHIHKHGLNPTEFAVLELLY HKGDQPLQQIGDKILLASGSITYVVDKLEQKELLIRKASPTDRRVTFAQITEKGIGLL NDIFPDHAAEIDEMISVLSEEEVEMCTEMLKRVGLNAKQFHNK*" gene 1433199..1433636 /gene="mhqR" /locus_tag="BSU_13670" /old_locus_tag="BSU13670" downshifts 1433619 /Source="Nicolas_upshifts" /id="D754" /incds=0 /nref=210 /ntot=257 /MaxReadThrough="1.20686" /MaxDrop="5.47215" /score="1.59181784" /energy="-8.9" /TU="U1110" /idTUdmin="U1110" /TUdmin="-22" /isTUend="TRUE" CDS complement(1433676..1434461) /gene="motB" /locus_tag="BSU_13680" /old_locus_tag="BSU13680" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:16095621, 18566286, 24296669, 24771657, 25273986" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16095621, 18566286, 24296669, 24771657, 25273986; Product type f: factor" /codon_start=1 /transl_table=11 /product="motility protein B; MotB component of the H+-coupled stator flagellum complex" /protein_id="NP_389251.1" /db_xref="EnsemblGenomes-Gn:BSU13680" /db_xref="EnsemblGenomes-Tr:CAB13241" /db_xref="GOA:P28612" /db_xref="InterPro:IPR006665" /db_xref="InterPro:IPR025713" /db_xref="InterPro:IPR036737" /db_xref="SubtiList:BG10689" /db_xref="UniProtKB/Swiss-Prot:P28612" /translation="MARKKKKKHEDEHVDESWLVPYADILTLLLALFIVLYASSSIDA AKFQMLSKSFNEVFTGGTGVLDYSSVTPPENESDGIDEVKKEKEEKEKNKKEKEKAAD QEELENVKSQVEKFIKDKKLEHQLETKMTSEGLLITIKDSIFFDSGKATIRKEDVPLA KEISNLLVINPPRNIIISGHTDNMPIKNSEFQSNWHLSVMRAVNFMGLLIENPKLDAK VFSAKGYGEYKPVASNKTAEGRSKNRRVEVLILPRGAAETNEK*" gene complement(1433676..1434461) /gene="motB" /locus_tag="BSU_13680" /old_locus_tag="BSU13680" downshifts complement(1433695) /Source="Nicolas_upshifts" /id="D755" /incds=0 /nref=224 /ntot=246 /MaxReadThrough="3.05351" /MaxDrop="6.69306" /score="21.3673767" /energy="-12.4" /TU="U1111" /idTUdmin="U1111" /TUdmin="-88" /isTUend="FALSE" downshifts complement(1434157) /Source="Nicolas_upshifts" /id="D756" /incds=1 /nref=1 /ntot=19 /MaxReadThrough="8.03566" /MaxDrop="4.69358" /score="21.3673767" /energy="-12.4" /TU="U1111" /idTUdmin="U1111" /TUdmin="-550" /isTUend="FALSE" CDS complement(1434433..1435245) /gene="motA" /locus_tag="BSU_13690" /old_locus_tag="BSU13690" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:16095621, 18566286, 24296669, 24771657, 25273986" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16095621, 18566286, 24296669, 24771657, 25273986; Product type f: factor" /codon_start=1 /transl_table=11 /product="motility protein A; MotA component of the H+-coupled stator flagellum complex" /protein_id="NP_389252.1" /db_xref="EnsemblGenomes-Gn:BSU13690" /db_xref="EnsemblGenomes-Tr:CAB13242" /db_xref="GOA:P28611" /db_xref="InterPro:IPR000540" /db_xref="InterPro:IPR002898" /db_xref="SubtiList:BG10688" /db_xref="UniProtKB/Swiss-Prot:P28611" /translation="MDKTSLIGIILAFVALSVGMVLKGVSFSALANPAAILIIIAGTI SAVVIAFPTKEIKKVPTLFRVLFKENKQLTIEELIPMFSEWAQLARREGLLALEASIE DVDDAFLKNGLSMAVDGQSAEFIRDIMTEEVEAMEDRHQAGAAIFTQAGTYAPTLGVL GAVIGLIAALSHMDNTDELGHAISAAFVATLLGIFTGYVLWHPFANKLKRKSKQEVKL REVMIEGVLSVLEGQAPKVIEQKLLMYLPAKDRLKFAEQGEAQNGEKKEEEA*" gene complement(1434433..1435245) /gene="motA" /locus_tag="BSU_13690" /old_locus_tag="BSU13690" promotor_-10 complement(1435276..1435294) /Source="Nicolas_upshift_promotors" /id="U1111" /multdbtbs="SigD" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2801 /SigmaFactorBS="tcttccttgaatatttcatgaacaaattcacaatgtcCCTAA AGTtccgggcaccaaaACCGATATTAACCATAGACaagctagtaaaaaaggatttggt g" /listShort="motA, motB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1435292) /Source="Nicolas_upshifts" /id="U1111" /multdbtbs="SigD" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2801 /SigmaFactorBS="tcttccttgaatatttcatgaacaaattcacaatgtcCCTAA AGTtccgggcaccaaaACCGATATTAACCATAGACaagctagtaaaaaaggatttggt g" /listShort="motA, motB" /GFF_Attribute="listLong" promotor_-35 complement(1435308..1435315) /Source="Nicolas_upshift_promotors" /id="U1111" /multdbtbs="SigD" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2801 /SigmaFactorBS="tcttccttgaatatttcatgaacaaattcacaatgtcCCTAA AGTtccgggcaccaaaACCGATATTAACCATAGACaagctagtaaaaaaggatttggt g" /listShort="motA, motB" /GFF_Attribute="listLong" /label="promotor_-35" S_feature complement(1435383..1435605) /Source="Nicolas_S_feature" /locus_tag="new_1435383_1435605_c" /HighExp="Diami, dia15, dia5, Heat, Etha, LPhT, H2O2, C30, G135, S7" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.93062599999999995" /TUshortSig="SigA" /TUshortPSig="0.671" /TUlongSig="NA" /TUlongPSig="NA" /label="S491" downshifts complement(1435415) /Source="Nicolas_upshifts" /id="D757" /incds=0 /nref=5 /ntot=12 /MaxReadThrough="0.48394" /MaxDrop="4.60081" /score="30.9355071" /energy="-15.4" /TU="NA" /idTUdmin="U1112" /TUdmin="-4" /isTUend="TRUE" CDS complement(1435628..1437727) /gene="clpE" /locus_tag="BSU_13700" /old_locus_tag="BSU13700" /function="16.3: Control" /function="16.6: Maintain" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:9987115, 10320580, 11069659, 14679237, 16788169, 16899079, 18689473, 19226326, 21208299, 28333276" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9987115, 10320580, 11069659, 14679237, 16788169, 16899079, 18689473, 19226326, 21208299, 28333276; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="ATP-dependent Clp protease (class III stress gene)" /protein_id="NP_389253.1" /db_xref="EnsemblGenomes-Gn:BSU13700" /db_xref="EnsemblGenomes-Tr:CAB13243" /db_xref="GOA:O31673" /db_xref="InterPro:IPR001270" /db_xref="InterPro:IPR001943" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR003959" /db_xref="InterPro:IPR018368" /db_xref="InterPro:IPR019489" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR028299" /db_xref="SubtiList:BG12578" /db_xref="UniProtKB/Swiss-Prot:O31673" /translation="MRCQHCHQNEATIRLNMQINSVHKQMVLCETCYNELTRKPSMSM GPQSFGFPFEQAFQPKEQSAAKQSEKKGLLDELAQNITNGAKAGLIDPVIGRDDEVAR VIEILNRRNKNNPVLIGEPGVGKTAIAEGLALKIAEGDVPNKLKNKELYLLDVASLVA NTGIRGQFEERMKQLITELKERKNVILFIDEIHLLVGAGSAEGSMDAGNILKPALARG ELQVIGATTLKEYRQIEKDAALERRFQPVMVQEPSIEQAILILQGIKDKYEAYHGVTF SDEAIKACVTLSSRYIQDRHLPDKAIDLLDEAGSKANLLIDELNDEDAAERLTAIEAE KTKALEEENYELAAKLRDEELALEKKLNSSSAHTAVTVEAEHIQEIVEQKTGIPVGKL QADEQTKMKELEAKLHERVIGQEAAVQKVAKAVRRSRAGLKSKNRPVGSFLFVGPTGV GKTELSKTLADELFGTKDAIIRLDMSEYMEKHAVSKIIGSPPGYVGHEEAGQLTEKVR RNPYSIVLLDEIEKAHPDVQHMFLQIMEDGRLTDSQGRTVSFKDTVIIMTSNAGAGEK QTKVGFQSDDSVIEEQTLIDSLSMFFKPEFLNRFDSIIEFRSLEKEHLVKIVSLLLGE LEETLAERGISLNVTDEAKEKIAELGYHPSFGARPLRRTIQEWVEDEMTDLLLDNGEI TSFHVILEDDKIKVRAK*" gene complement(1435628..1437727) /gene="clpE" /locus_tag="BSU_13700" /old_locus_tag="BSU13700" downshifts complement(1435650) /Source="Nicolas_upshifts" /id="D758" /incds=0 /nref=27 /ntot=132 /MaxReadThrough="4.1802" /MaxDrop="6.07862" /score="41.2563375" /energy="-13.6" /TU="U1112" /idTUdmin="U1112" /TUdmin="-239" /isTUend="FALSE" S_feature complement(1437728..1437978) /Source="Nicolas_S_feature" /locus_tag="new_1437728_1437978_c" /HighExp="dia5, Heat, Diami, LPhT, dia15, H2O2, HiTm, S2, Cold, S1" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.671" /TUlongSig="NA" /TUlongPSig="NA" /label="S492" promotor_no_box complement(1437938..1438038) /Source="Nicolas_upshift_promotors" /id="U1112" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.437562437562438" /psig="0.671328671328671" /xcortree=2025 /SigmaFactorBS="atgagacaagttccttgaaaagacgaagaaaacatgttttac tttgtaacaaatcaaaaatttttgtgcataagacttgaaagtcaaagatagtcagagt a" /listShort="S492, clpE, S491" /GFF_Attribute="listLong" /label="promotor_no_box" upshifts complement(1437978) /Source="Nicolas_upshifts" /id="U1112" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.437562437562438" /psig="0.671328671328671" /xcortree=2025 /SigmaFactorBS="atgagacaagttccttgaaaagacgaagaaaacatgttttac tttgtaacaaatcaaaaatttttgtgcataagacttgaaagtcaaagatagtcagagt a" /listShort="S492, clpE, S491" /GFF_Attribute="listLong" promotor_-35 1438014..1438019 /Source="Nicolas_upshift_promotors" /id="U1113" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=984 /SigmaFactorBS="tgcacaaaaatttttgatttgttacaaagtaaaacatgtttt cttCGTCTTttcaaggaacttgtcTCATAGGTTATAAAAAGGCatatatggacaaaac t" /listShort="ykvI, S493" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 1438029 /Source="Nicolas_upshifts" /id="U1113" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=984 /SigmaFactorBS="tgcacaaaaatttttgatttgttacaaagtaaaacatgtttt cttCGTCTTttcaaggaacttgtcTCATAGGTTATAAAAAGGCatatatggacaaaac t" /listShort="ykvI, S493" /GFF_Attribute="listLong" promotor_-10 1438035..1438053 /Source="Nicolas_upshift_promotors" /id="U1113" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=984 /SigmaFactorBS="tgcacaaaaatttttgatttgttacaaagtaaaacatgtttt cttCGTCTTttcaaggaacttgtcTCATAGGTTATAAAAAGGCatatatggacaaaac t" /listShort="ykvI, S493" /GFF_Attribute="listLong" /label="promotor_-10" CDS 1438092..1439135 /gene="ykvI" /locus_tag="BSU_13710" /old_locus_tag="BSU13710" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15383836, 15849754, 16850406, 26735940; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative transporter" /protein_id="NP_389254.1" /db_xref="EnsemblGenomes-Gn:BSU13710" /db_xref="EnsemblGenomes-Tr:CAB13244" /db_xref="GOA:O31674" /db_xref="SubtiList:BG13311" /db_xref="UniProtKB/Swiss-Prot:O31674" /translation="MEQSKGSASQLAFVYVGTVVGAGFATGREIVEFFLKFGWFGFFG ILVSGGMFTLLGAKLMIISKRINAKSYQEMNIFLFGATAGRIINVFMLFVLLGVTSVM LSGAGALFEEQLGMSAQIGMLITIGLSLIVMTRGVKGIFGVNVFVVPLLIIFSMIVVA DSFIFSESRNAAQWVWPHRWDWLLSAVSYGALNLSLAQAVLVPLANEMSSEKVIKKGA LIGGTMLTIVLSASFLSLSTLPDVFLYDIPMAQVVYLFARSVHLIYLLIIFGEVFTSV IGNLYGLEKQVQSFLPVKSKYIFAAIMITAYITSQIGYGRLISTIYPLFGYVSLAFIG ALLCKKAPRRRSL*" gene 1438092..1439135 /gene="ykvI" /locus_tag="BSU_13710" /old_locus_tag="BSU13710" S_feature 1439136..1439227 /Source="Nicolas_S_feature" /locus_tag="new_1439136_1439227" /HighExp="S3, LoTm, S4, S5, BT, M9-stat, S6, T5.0H, T4.0H, Pyr" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigEF" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S493" promotor_-35 1439204..1439208 /Source="Nicolas_upshift_promotors" /id="U1114" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.906093906093906" /psig=1 /xcortree=2483 /SigmaFactorBS="cgataattgatctaggaaccggggactgactttttTATTGtc aagaaaaacatcatTATGGTAAGATAGCAGAAGTgaaaaaattgaagaaaatccgtgc g" /listShort="NA, S494, queC, queD, queE, queF, S495" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1439225..1439244 /Source="Nicolas_upshift_promotors" /id="U1114" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.906093906093906" /psig=1 /xcortree=2483 /SigmaFactorBS="cgataattgatctaggaaccggggactgactttttTATTGtc aagaaaaacatcatTATGGTAAGATAGCAGAAGTgaaaaaattgaagaaaatccgtgc g" /listShort="NA, S494, queC, queD, queE, queF, S495" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1439229 /Source="Nicolas_upshifts" /id="U1114" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.906093906093906" /psig=1 /xcortree=2483 /SigmaFactorBS="cgataattgatctaggaaccggggactgactttttTATTGtc aagaaaaacatcatTATGGTAAGATAGCAGAAGTgaaaaaattgaagaaaatccgtgc g" /listShort="NA, S494, queC, queD, queE, queF, S495" /GFF_Attribute="listLong" misc_RNA 1439274..1439318 /gene="qswA" /locus_tag="BSU_misc_RNA_22" /product="preQ1 riboswitch" /experiment="publication(s) with functional evidences, PMID:17384645, 19234468, 19285444, 20534493, 21410253, 21592962, 24798077, 27484311" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 17384645, 19234468, 19285444, 20534493, 21410253, 21592962, 24798077, 27484311; Product type n: RNA" /function="16.3: Control" gene 1439274..1439318 /gene="qswA" /locus_tag="BSU_misc_RNA_22" downshifts 1439295 /Source="Nicolas_upshifts" /id="D759" /incds=0 /nref=11 /ntot=17 /MaxReadThrough="7.29177" /MaxDrop="4.09959" /score="21.1398563" /energy="-9.5" /TU="U1114" /idTUdmin="U1113" /TUdmin=0 /isTUend="TRUE" S_feature 1439340..1439447 /Source="Nicolas_S_feature" /locus_tag="new_1439340_1439447" /HighExp="Paraq, ferm, G180, LBGstat, Diami, H2O2, LPhT, Oxctl, G135, G150" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S494" CDS 1439448..1440107 /gene="queC" /locus_tag="BSU_13720" /old_locus_tag="BSU13720" /EC_number="6.3.4.20" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:14660578, 16199558, 17384645, 18491386, 19354300" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 14660578, 16199558, 17384645, 18491386, 19354300; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="pre-queuosine 0 synthase" /protein_id="NP_389255.1" /db_xref="EnsemblGenomes-Gn:BSU13720" /db_xref="EnsemblGenomes-Tr:CAB13245" /db_xref="GOA:O31675" /db_xref="InterPro:IPR014729" /db_xref="InterPro:IPR018317" /db_xref="PDB:3BL5" /db_xref="SubtiList:BG13312" /db_xref="UniProtKB/Swiss-Prot:O31675" /translation="MKKEKAIVVFSGGQDSTTCLLWALKEFEEVETVTFHYNQRHSQE VEVAKSIAEKLGVKNHLLDMSLLNQLAPNALTRNDIEIEVKDGELPSTFVPGRNLVFL SFASILAYQIGARHIITGVCETDFSGYPDCRDEFVKSCNVTVNLAMEKPFVIHTPLMW LNKAETWKLADELGALDFVKNNTLTCYNGIIADGCGECPACHLRSKGYEEYMVMKGER A*" gene 1439448..1440107 /gene="queC" /locus_tag="BSU_13720" /old_locus_tag="BSU13720" CDS 1440100..1440549 /gene="queD" /locus_tag="BSU_13730" /old_locus_tag="BSU13730" /EC_number="4.1.2.50" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:12123838, 14660578, 16199558, 18259064, 19231875" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12123838, 14660578, 16199558, 18259064, 19231875; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="6-carboxy-5,6,7,8-tetrahydropterin synthase; queuosine biosynthesis" /protein_id="NP_389256.1" /db_xref="EnsemblGenomes-Gn:BSU13730" /db_xref="EnsemblGenomes-Tr:CAB13246" /db_xref="GOA:O31676" /db_xref="InterPro:IPR007115" /db_xref="SubtiList:BG13313" /db_xref="UniProtKB/Swiss-Prot:O31676" /translation="MHKLLSQIYPQAQHPYSFELNKDMHISAAHFIPRESAGACSRVH GHTYTVNITVAGDELDDSGFLVNFSVLKKLVHGNYDHTLLNDHEDFSQDDRYSLPTTE VVAKTIYDNVQAYLDTLENKPTCVQVFVRETPTSYCVYRPKKGGLNG*" gene 1440100..1440549 /gene="queD" /locus_tag="BSU_13730" /old_locus_tag="BSU13730" CDS 1440542..1441273 /gene="queE" /locus_tag="BSU_13740" /old_locus_tag="BSU13740" /EC_number="4.3.99.3" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:12123838, 14660578, 16199558, 19354300, 23194065" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12123838, 14660578, 16199558, 19354300, 23194065; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="7-carboxy-7-deazaguanine synthase" /protein_id="NP_389257.1" /db_xref="EnsemblGenomes-Gn:BSU13740" /db_xref="EnsemblGenomes-Tr:CAB13247" /db_xref="GOA:O31677" /db_xref="InterPro:IPR007197" /db_xref="InterPro:IPR017742" /db_xref="InterPro:IPR023404" /db_xref="InterPro:IPR024924" /db_xref="PDB:5TGS" /db_xref="PDB:5TH5" /db_xref="SubtiList:BG13314" /db_xref="UniProtKB/Swiss-Prot:O31677" /translation="MAKGIPVLEIFGPTIQGEGMVIGQKTMFVRTAGCDYSCSWCDSA FTWDGSAKKDIRWMTAEEIFAELKDIGGDAFSHVTISGGNPALLKQLDAFIELLKENN IRAALETQGTVYQDWFTLIDDLTISPKPPSSKMVTNFQKLDHILTSLQENDRQHAVSL KVVIFNDEDLEFAKTVHKRYPGIPFYLQVGNDDVHTTDDQSLIAHLLGKYEALVDKVA VDAELNLVRVLPQLHTLLWGNKRGV*" gene 1440542..1441273 /gene="queE" /locus_tag="BSU_13740" /old_locus_tag="BSU13740" CDS 1441291..1441788 /gene="queF" /locus_tag="BSU_13750" /old_locus_tag="BSU13750" /EC_number="1.7.1.13" /function="10.3: tRNA and rRNA base modification" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:12123838, 14660578, 16199558, 17929836, 22938038, 23410922, 28300774" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12123838, 14660578, 16199558, 17929836, 22938038, 23410922, 28300774; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="NADPH-dependent 7-cyano-7-deazaguanine reductase" /protein_id="NP_389258.1" /db_xref="EnsemblGenomes-Gn:BSU13750" /db_xref="EnsemblGenomes-Tr:CAB13248" /db_xref="GOA:O31678" /db_xref="InterPro:IPR016856" /db_xref="InterPro:IPR029500" /db_xref="PDB:4F8B" /db_xref="PDB:4FGC" /db_xref="PDB:5UDG" /db_xref="SubtiList:BG13315" /db_xref="UniProtKB/Swiss-Prot:O31678" /translation="MTTRKESELEGVTLLGNQGTNYLFEYAPDVLESFPNKHVNRDYF VKFNCPEFTSLCPKTGQPDFATIYISYIPDEKMVESKSLKLYLFSFRNHGDFHEDCMN IIMNDLIELMDPRYIEVWGKFTPRGGISIDPYTNYGKPGTKYEKMAEYRMMNHDLYPE TIDNR*" gene 1441291..1441788 /gene="queF" /locus_tag="BSU_13750" /old_locus_tag="BSU13750" S_feature 1441789..1442065 /Source="Nicolas_S_feature" /locus_tag="new_1441789_1442065" /HighExp="Paraq, ferm, LPhT, C30, G135, G180, LBGstat, Oxctl, G150, Diami" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S495" downshifts 1442023 /Source="Nicolas_upshifts" /id="D760" /incds=0 /nref=200 /ntot=247 /MaxReadThrough="1.17154" /MaxDrop="6.60953" /score="11.1883045" /energy="-7.8" /TU="NA" /idTUdmin="U1114" /TUdmin=0 /isTUend="TRUE" downshifts complement(1442033) /Source="Nicolas_upshifts" /id="D761" /incds=0 /nref=1 /ntot=4 /MaxReadThrough="1.54726" /MaxDrop="2.16508" /score="6.24357423" /energy="-7.6" /TU="NA" /idTUdmin="U1115" /TUdmin=110 /isTUend="FALSE" S_feature complement(1442102..1442346) /Source="Nicolas_S_feature" /locus_tag="new_1442102_1442346_c" /HighExp="Diami, dia5, LPhT, Etha, Salt, dia15, Heat, HiTm, C30, HiOs" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.15795400000000001" /TUshortSig="SigA" /TUshortPSig="0.997" /TUlongSig="NA" /TUlongPSig="NA" /label="S496" downshifts complement(1442143) /Source="Nicolas_upshifts" /id="D762" /incds=0 /nref=47 /ntot=193 /MaxReadThrough="2.13712" /MaxDrop="5.08206" /score="6.24357423" /energy="-7.6" /TU="NA" /idTUdmin="U1115" /TUdmin=0 /isTUend="TRUE" CDS complement(1442347..1442703) /gene="ykvN" /locus_tag="BSU_13760" /old_locus_tag="BSU13760" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 16683018; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative transcriptional regulator (HGT island)" /protein_id="NP_389259.1" /db_xref="EnsemblGenomes-Gn:BSU13760" /db_xref="EnsemblGenomes-Tr:CAB13249" /db_xref="GOA:O31679" /db_xref="InterPro:IPR002577" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG13316" /db_xref="UniProtKB/Swiss-Prot:O31679" /translation="MKKFSCGFEVTKEVIGGKWKGLVLYFLMNGPKRTSELKRIIPNI TQKMLIQTLRELEASGLVSRKMYNQVPPKVEYSSTELGESLKPILQELCQWGGYYAEQ EYAEGEYEIVQPEQLS*" gene complement(1442347..1442703) /gene="ykvN" /locus_tag="BSU_13760" /old_locus_tag="BSU13760" misc_feature complement(1442734..1442753) /Source="Nicolas_upshift_promotors" /id="U1115" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.727272727272727" /psig="0.997002997002997" /xcortree=1897 /SigmaFactorBS="acaacttacaagatatagtatccttcagtaagcacattatcg gaagtacccactttttTGTGATATAGTAACTAAAAAgtaataaatgtggaatggagag c" /listShort="ykvN, S496" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(1442751) /Source="Nicolas_upshifts" /id="U1115" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.727272727272727" /psig="0.997002997002997" /xcortree=1897 /SigmaFactorBS="acaacttacaagatatagtatccttcagtaagcacattatcg gaagtacccactttttTGTGATATAGTAACTAAAAAgtaataaatgtggaatggagag c" /listShort="ykvN, S496" /GFF_Attribute="listLong" promotor_-35 1442769 /Source="Nicolas_upshift_promotors" /id="U1116" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.313686313686314" /psig="0.954045954045954" /xcortree=1793 /SigmaFactorBS="ctttttagttactatatcacaaaaaagtgggtacttCcgata atgtgcttactgaAGGATACTATATCTTGTAAgttgttcttcaagtacttaaaggtac t" /listShort="ykvO" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1442788..1442806 /Source="Nicolas_upshift_promotors" /id="U1116" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.313686313686314" /psig="0.954045954045954" /xcortree=1793 /SigmaFactorBS="ctttttagttactatatcacaaaaaagtgggtacttCcgata atgtgcttactgaAGGATACTATATCTTGTAAgttgttcttcaagtacttaaaggtac t" /listShort="ykvO" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1442793 /Source="Nicolas_upshifts" /id="U1116" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.313686313686314" /psig="0.954045954045954" /xcortree=1793 /SigmaFactorBS="ctttttagttactatatcacaaaaaagtgggtacttCcgata atgtgcttactgaAGGATACTATATCTTGTAAgttgttcttcaagtacttaaaggtac t" /listShort="ykvO" /GFF_Attribute="listLong" CDS 1442872..1443618 /gene="ykvO" /locus_tag="BSU_13770" /old_locus_tag="BSU13770" /EC_number="1.-.-.-" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 16683018, 26494135; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative oxidoreductase (HGT island)" /protein_id="NP_389260.1" /db_xref="EnsemblGenomes-Gn:BSU13770" /db_xref="EnsemblGenomes-Tr:CAB13250" /db_xref="GOA:O31680" /db_xref="InterPro:IPR002347" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG13317" /db_xref="UniProtKB/Swiss-Prot:O31680" /translation="MGKFEGKIALVTGGTSGIGLATAQKFVNEGAYVYITGRRQNELD KAVNQIGKNVTGVQGDISKLEDLDKLYDIIKQEKGKLDILFANAGIGNFLPLGEITEE QVDRTFDINVKGTIFTVQKALSLFPDKVGSIIVTGSTAGSIGNPAFSVYGASKAALRA LVRNWILDLKGTEIRVNVVSPGGILTPAYDELFGDALEEVLENSRNTVPAGKVGTPEE VANAVSFLASDESSYLTGVELFVDGGLAQV*" gene 1442872..1443618 /gene="ykvO" /locus_tag="BSU_13770" /old_locus_tag="BSU13770" downshifts 1443673 /Source="Nicolas_upshifts" /id="D763" /incds=0 /nref=19 /ntot=146 /MaxReadThrough="0.723690000000001" /MaxDrop="4.37163" /score="1.34631843" /energy="-9.1" /TU="NA" /idTUdmin="U1116" /TUdmin=0 /isTUend="TRUE" promotor_-35 1444021..1444029 /Source="Nicolas_upshift_promotors" /id="U1117" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=1420 /SigmaFactorBS="tctcgtgatctcacacctgaacgttttttatagaCTAGTACC GcgacaagttatatTACATATACATACCAATAAAgtagacattaaaaagtgaaagaga g" /listShort="ykvP, ykzQ, S497, ykvQ, ykzR" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1444043..1444062 /Source="Nicolas_upshift_promotors" /id="U1117" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=1420 /SigmaFactorBS="tctcgtgatctcacacctgaacgttttttatagaCTAGTACC GcgacaagttatatTACATATACATACCAATAAAgtagacattaaaaagtgaaagaga g" /listShort="ykvP, ykzQ, S497, ykvQ, ykzR" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1444047 /Source="Nicolas_upshifts" /id="U1117" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=1420 /SigmaFactorBS="tctcgtgatctcacacctgaacgttttttatagaCTAGTACC GcgacaagttatatTACATATACATACCAATAAAgtagacattaaaaagtgaaagaga g" /listShort="ykvP, ykzQ, S497, ykvQ, ykzR" /GFF_Attribute="listLong" CDS 1444099..1445298 /gene="ykvP" /locus_tag="BSU_13780" /old_locus_tag="BSU13780" /function="16.8: Protect" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:11011148, 16683018" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11011148, 16683018; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="spore protein (HGT island)" /protein_id="NP_389261.1" /db_xref="EnsemblGenomes-Gn:BSU13780" /db_xref="EnsemblGenomes-Tr:CAB13251" /db_xref="GOA:O31681" /db_xref="InterPro:IPR018392" /db_xref="InterPro:IPR036779" /db_xref="SubtiList:BG13318" /db_xref="UniProtKB/Swiss-Prot:O31681" /translation="MKILFLESHPMWLYGLPNGFREAGHTVMISGPVSRENITEMIDE FKPDLIVSMGWTPEHSREKQAWIRNATKKVNIPLVYWATEDPLHTQNFTIPLIKKMKP DFVFTVTPSLCKTYESMGIKAAHLDFAFHESIHHQIKPLAKYSCDIAVVANAYPNFLE EHPEVFRSSSLKTLIRPLIRKGIRIDFWGRNWEKMSKYIGREIPRNWIHGYLDYTEAY KVYSSAKIIIGLQNCESQLTQRTYEILGSGGFLLTSDTPAVRGKFKPGRDLIVSSSPK ETLEKVKYYLNHDSERKKIQINGKKAVKNDSYRHRAERMLEVLKSRGIIRNLGETIHY VDVLKEKYVIHHVTPGETLSIIASKYNVSLQQLMELNHFKSDQIYAGQIIKIREKLFR NINNKLF*" gene 1444099..1445298 /gene="ykvP" /locus_tag="BSU_13780" /old_locus_tag="BSU13780" promotor_-35 1444181..1444187 /Source="Nicolas_upshift_promotors" /id="U1118" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=152 /SigmaFactorBS="cgaatgggtttagggaagcaggacataccgtaaTGATTTCcg gtcctgtaagtcGGGAAAATATAACTGAAATgatagacgaatttaaaccagatttaat a" /listShort="ykzQ, S497, ykvQ" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1444202..1444220 /Source="Nicolas_upshift_promotors" /id="U1118" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=152 /SigmaFactorBS="cgaatgggtttagggaagcaggacataccgtaaTGATTTCcg gtcctgtaagtcGGGAAAATATAACTGAAATgatagacgaatttaaaccagatttaat a" /listShort="ykzQ, S497, ykvQ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1444208 /Source="Nicolas_upshifts" /id="U1118" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=152 /SigmaFactorBS="cgaatgggtttagggaagcaggacataccgtaaTGATTTCcg gtcctgtaagtcGGGAAAATATAACTGAAATgatagacgaatttaaaccagatttaat a" /listShort="ykzQ, S497, ykvQ" /GFF_Attribute="listLong" promotor_-35 1445267..1445269 /Source="Nicolas_upshift_promotors" /id="U1119" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.346653346653347" /psig="0.602397602397602" /xcortree=2158 /SigmaFactorBS="acaaatcattaagattagagagaaacTGTttagaaatattaa taacaaATTATTCTAAAGGAGAGTAatatgaatgaaggggaaaatacctaaaataaga a" /listShort="ykzQ, S497, ykvQ" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1445289..1445307 /Source="Nicolas_upshift_promotors" /id="U1119" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.346653346653347" /psig="0.602397602397602" /xcortree=2158 /SigmaFactorBS="acaaatcattaagattagagagaaacTGTttagaaatattaa taacaaATTATTCTAAAGGAGAGTAatatgaatgaaggggaaaatacctaaaataaga a" /listShort="ykzQ, S497, ykvQ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1445301 /Source="Nicolas_upshifts" /id="U1119" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.346653346653347" /psig="0.602397602397602" /xcortree=2158 /SigmaFactorBS="acaaatcattaagattagagagaaacTGTttagaaatattaa taacaaATTATTCTAAAGGAGAGTAatatgaatgaaggggaaaatacctaaaataaga a" /listShort="ykzQ, S497, ykvQ" /GFF_Attribute="listLong" CDS 1445314..1445541 /gene="ykzQ" /locus_tag="BSU_13789" /old_locus_tag="BSU13789" /function="16.13: Shape" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type f: factor" /codon_start=1 /transl_table=11 /product="putative peptidoglycan binding protein" /protein_id="YP_003097719.1" /db_xref="EnsemblGenomes-Gn:BSU13789" /db_xref="EnsemblGenomes-Tr:CAX52610" /db_xref="InterPro:IPR018392" /db_xref="InterPro:IPR036779" /db_xref="UniProtKB/Swiss-Prot:C0H403" /translation="MKGKIPKIRNQANKVKRTPRYMEFPVTYEVYHVESGDTLWTIAK SFEIPVQQLMNLNKLSSDRIYPGQIIKIRER*" gene 1445314..1445541 /gene="ykzQ" /locus_tag="BSU_13789" /old_locus_tag="BSU13789" misc_feature complement(1445391..1445410) /Source="Nicolas_upshift_promotors" /id="U1120" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.937062937062937" /psig="0.982017982017982" /xcortree=2163 /SigmaFactorBS="ggaatttcaaaggatttggcaatcgtccataatgtatcgccg gattccaCATGATATACTTCGTATGTCacgggaaattccatataacgaggcgttcttt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(1445399) /Source="Nicolas_upshifts" /id="U1120" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.937062937062937" /psig="0.982017982017982" /xcortree=2163 /SigmaFactorBS="ggaatttcaaaggatttggcaatcgtccataatgtatcgccg gattccaCATGATATACTTCGTATGTCacgggaaattccatataacgaggcgttcttt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" S_feature 1445542..1445637 /Source="Nicolas_S_feature" /locus_tag="new_1445542_1445637" /HighExp="BT, S8, B36, S7, Etha, S6, G/S, LBGstat, Pyr, Salt" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigB, SigK" /TUshortPSig="0.602, 0.999, 0.997" /TUlongSig="NA" /TUlongPSig="NA" /label="S497" CDS 1445638..1446336 /gene="ykvQ" /locus_tag="BSU_13790" /old_locus_tag="BSU13790" /EC_number="3.2.-.-" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 16683018; Product type e: enzyme" /pseudo /codon_start=1 /transl_table=11 /product="putative sporulation-specific glycosylase (HGT island)" /db_xref="EnsemblGenomes-Gn:BSU13790" /db_xref="EnsemblGenomes-Tr:CAB13252" /db_xref="GOA:O31682" /db_xref="InterPro:IPR001223" /db_xref="InterPro:IPR011583" /db_xref="InterPro:IPR017853" /db_xref="PSEUDO:CAB13252.1" /db_xref="SubtiList:BG13319" /db_xref="UniProtKB/Swiss-Prot:O31682" /translation="MFQMSYYYSGLGWDFIQHVDQTNGVLNVVSPDFFYIRKDGSLLL RSANPDVIKALHRRKLKVVPFLSNHWDQDLGRFALMNRVLLAKQISHAIEELDLDGVN IDIENLTEKDRNLFTDFIRLVRKSIPRHKEVSVAVAANPFGWTKGWHGSYDYEYLAKY ADYLMVMAYDESRLAGPTASVGWVEKSIQYVLTQKISPQKLVLGLPFYGRCWMEGQSA SQAIPLYLVVSKKA*" gene 1445638..1446336 /gene="ykvQ" /locus_tag="BSU_13790" /old_locus_tag="BSU13790" /pseudo S_feature complement(1446289..1447115) /Source="Nicolas_S_feature" /locus_tag="new_1446289_1447115_c" /HighExp="H2O2, M40t90, S8, M40t45, LPhT, Sw, Cold, LBGstat, C30, dia15" /AntisenseName="ykzR" /AntisenseCor="0.170402182980955" /AntisenseRegPval="-2.2999999999999998" /CDS_PredictionProba="0.38670900000000002" /TUshortSig="SigA" /TUshortPSig="0.986" /TUlongSig="NA" /TUlongPSig="NA" /label="S498" CDS 1446317..1446568 /gene="ykzR" /locus_tag="BSU_13799" /old_locus_tag="BSU13799" /function="16.8: Protect" /function="16.13: Shape" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 16683018; Product type e: enzyme" /pseudo /codon_start=1 /transl_table=11 /product="putative spore-specific glycosyl hydrolase" /db_xref="EnsemblGenomes-Gn:BSU13799" /db_xref="EnsemblGenomes-Tr:CAX52611" /db_xref="GOA:C0H404" /db_xref="InterPro:IPR017853" /db_xref="PSEUDO:CAX52611.1" /db_xref="UniProtKB/Swiss-Prot:C0H404" /translation="MLVKRHSGTIIFDTKSQSPKAIFTVNHDKKGPLPSGTYTLWFEN EQSLRAKIKLAQKYNLKGLGSWSLGQEDASVWNTVFKNI*" gene 1446317..1446568 /gene="ykzR" /locus_tag="BSU_13799" /old_locus_tag="BSU13799" /pseudo misc_feature 1446818..1446833 /Source="Nicolas_upshift_promotors" /id="U1121" /multdbtbs="-" /comp="M18" /sig="SigL" /pcomp="0.516483516483517" /psig="0.516483516483517" /xcortree=2456 /SigmaFactorBS="ctgcttccatgatttaatcatacacatgctacttgatAGCAG GGTTATCGCATttcattcagaattgttcaggatcgatatggaagcgcacgactaacta g" /listShort="S499" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" S_feature 1446841..1447052 /Source="Nicolas_S_feature" /locus_tag="new_1446841_1447052" /HighExp="Diami, S8, dia15, G180, HPh, C30, Paraq, H2O2, Salt, G135" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigL" /TUshortPSig="0.516" /TUlongSig="NA" /TUlongPSig="NA" /label="S499" upshifts 1446841 /Source="Nicolas_upshifts" /id="U1121" /multdbtbs="-" /comp="M18" /sig="SigL" /pcomp="0.516483516483517" /psig="0.516483516483517" /xcortree=2456 /SigmaFactorBS="ctgcttccatgatttaatcatacacatgctacttgatAGCAG GGTTATCGCATttcattcagaattgttcaggatcgatatggaagcgcacgactaacta g" /listShort="S499" /GFF_Attribute="listLong" downshifts 1447017 /Source="Nicolas_upshifts" /id="D764" /incds=0 /nref=2 /ntot=72 /MaxReadThrough="2.59168" /MaxDrop="2.74537" /score="-4.38958816" /energy="-9" /TU="NA" /idTUdmin="U1121" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(1447104..1447123) /Source="Nicolas_upshift_promotors" /id="U1122" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.879120879120879" /psig="0.986013986013986" /xcortree=1501 /SigmaFactorBS="gttcttaacggttatatgaaccaattcattcgaaaagacaCC TTTACAaacatacgttcgttaAATTATAATAAAACAGACGAgctgccatccagcatcc c" /listShort="S498" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1447126) /Source="Nicolas_upshifts" /id="U1122" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.879120879120879" /psig="0.986013986013986" /xcortree=1501 /SigmaFactorBS="gttcttaacggttatatgaaccaattcattcgaaaagacaCC TTTACAaacatacgttcgttaAATTATAATAAAACAGACGAgctgccatccagcatcc c" /listShort="S498" /GFF_Attribute="listLong" promotor_-35 complement(1447139..1447146) /Source="Nicolas_upshift_promotors" /id="U1122" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.879120879120879" /psig="0.986013986013986" /xcortree=1501 /SigmaFactorBS="gttcttaacggttatatgaaccaattcattcgaaaagacaCC TTTACAaacatacgttcgttaAATTATAATAAAACAGACGAgctgccatccagcatcc c" /listShort="S498" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1447191..1447198 /Source="Nicolas_upshift_promotors" /id="U1123" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.8001998001998" /psig=1 /xcortree=2042 /SigmaFactorBS="cgaatgaattggttcatataaccgttaagaacagatTCATTG TAaacattcgctaaggTATGCTAAGATGCATGGACTataaaggagtgatatgaagtga a" /listShort="ykvR" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1447213..1447232 /Source="Nicolas_upshift_promotors" /id="U1123" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.8001998001998" /psig=1 /xcortree=2042 /SigmaFactorBS="cgaatgaattggttcatataaccgttaagaacagatTCATTG TAaacattcgctaaggTATGCTAAGATGCATGGACTataaaggagtgatatgaagtga a" /listShort="ykvR" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1447215 /Source="Nicolas_upshifts" /id="U1123" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.8001998001998" /psig=1 /xcortree=2042 /SigmaFactorBS="cgaatgaattggttcatataaccgttaagaacagatTCATTG TAaacattcgctaaggTATGCTAAGATGCATGGACTataaaggagtgatatgaagtga a" /listShort="ykvR" /GFF_Attribute="listLong" CDS 1447251..1447541 /gene="ykvR" /locus_tag="BSU_13800" /old_locus_tag="BSU13800" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein (HGT island)" /protein_id="NP_389263.1" /db_xref="EnsemblGenomes-Gn:BSU13800" /db_xref="EnsemblGenomes-Tr:CAB13253" /db_xref="InterPro:IPR021596" /db_xref="InterPro:IPR023105" /db_xref="PDB:2JN9" /db_xref="SubtiList:BG13320" /db_xref="UniProtKB/Swiss-Prot:O31683" /translation="MKTLRLNNVTLEMAAYQEESEPKRKIAFTLNVTSETYHDIAVLL YEKTFNVEVPERDLAFRGEMTNYSTSLTNLYEPGAVSEFYIEITEIDKNADS*" gene 1447251..1447541 /gene="ykvR" /locus_tag="BSU_13800" /old_locus_tag="BSU13800" S_feature complement(1447578..1447661) /Source="Nicolas_S_feature" /locus_tag="new_1447578_1447661_c" /HighExp="Etha, dia5, Salt, SMMPr, Lbtran, dia15, Heat, S4, HiOs, HiTm" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.995" /TUlongSig="NA" /TUlongPSig="NA" /label="S500" downshifts complement(1447621) /Source="Nicolas_upshifts" /id="D765" /incds=0 /nref=216 /ntot=257 /MaxReadThrough="2.80569" /MaxDrop="6.83857" /score="21.3524751" /energy="-9.9" /TU="U1124" /idTUdmin="U1126" /TUdmin=0 /isTUend="TRUE" CDS complement(1447662..1447847) /gene="ykvS" /locus_tag="BSU_13810" /old_locus_tag="BSU13810" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function (HGT island)" /protein_id="NP_389264.2" /db_xref="EnsemblGenomes-Gn:BSU13810" /db_xref="EnsemblGenomes-Tr:CAB13254" /db_xref="InterPro:IPR018690" /db_xref="SubtiList:BG13321" /db_xref="UniProtKB/Swiss-Prot:O31684" /translation="MKIAKVGNVIEFKNGLTGVVEKVNENSVIVDVTIMDNYRDLELD SLTVVNHKNYKIIRDSY*" gene complement(1447662..1447847) /gene="ykvS" /locus_tag="BSU_13810" /old_locus_tag="BSU13810" promotor_-10 complement(1447880..1447899) /Source="Nicolas_upshift_promotors" /id="U1124" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.665334665334665" /psig="0.995004995004995" /xcortree=2222 /SigmaFactorBS="aacaattcataagggagataaaactccttatCGCTTTACttc tcaatgaaaaTACTGCAAAATACTTTCAAAaggcattattatgtttaaaggagaggaa g" /listShort="ykvS, S500" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1447891) /Source="Nicolas_upshifts" /id="U1124" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.665334665334665" /psig="0.995004995004995" /xcortree=2222 /SigmaFactorBS="aacaattcataagggagataaaactccttatCGCTTTACttc tcaatgaaaaTACTGCAAAATACTTTCAAAaggcattattatgtttaaaggagaggaa g" /listShort="ykvS, S500" /GFF_Attribute="listLong" S_feature complement(1447893..1448237) /Source="Nicolas_S_feature" /locus_tag="new_1447893_1448237_c" /HighExp="S4, S8, S6, S5, S3, T5.0H, LoTm, S7, T4.0H, BT" /AntisenseName="ykzS" /AntisenseCor="-0.65556958045860303" /AntisenseRegPval="-33.700000000000003" /CDS_PredictionProba="NA" /TUshortSig="SigEF" /TUshortPSig="0.987" /TUlongSig="NA" /TUlongPSig="NA" /label="S501" promotor_-35 complement(1447913..1447920) /Source="Nicolas_upshift_promotors" /id="U1124" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.665334665334665" /psig="0.995004995004995" /xcortree=2222 /SigmaFactorBS="aacaattcataagggagataaaactccttatCGCTTTACttc tcaatgaaaaTACTGCAAAATACTTTCAAAaggcattattatgtttaaaggagaggaa g" /listShort="ykvS, S500" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1447946..1447951 /Source="Nicolas_upshift_promotors" /id="U1125" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.664335664335664" /psig="0.999000999001" /xcortree=1831 /SigmaFactorBS="taaagcgataaggagttttatctcccttatgaATTGTTctgt cgctataaagaTGATATATTGATTTTCGTCAatagaaagaaaaggggggaatttttgt t" /listShort="ykzS, ykvT" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1447967..1447986 /Source="Nicolas_upshift_promotors" /id="U1125" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.664335664335664" /psig="0.999000999001" /xcortree=1831 /SigmaFactorBS="taaagcgataaggagttttatctcccttatgaATTGTTctgt cgctataaagaTGATATATTGATTTTCGTCAatagaaagaaaaggggggaatttttgt t" /listShort="ykzS, ykvT" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1447974 /Source="Nicolas_upshifts" /id="U1125" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.664335664335664" /psig="0.999000999001" /xcortree=1831 /SigmaFactorBS="taaagcgataaggagttttatctcccttatgaATTGTTctgt cgctataaagaTGATATATTGATTTTCGTCAatagaaagaaaaggggggaatttttgt t" /listShort="ykzS, ykvT" /GFF_Attribute="listLong" CDS 1448013..1448207 /gene="ykzS" /locus_tag="BSU_13819" /old_locus_tag="BSU13819" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein (HGT island)" /protein_id="YP_003097721.1" /db_xref="EnsemblGenomes-Gn:BSU13819" /db_xref="EnsemblGenomes-Tr:CAX52612" /db_xref="UniProtKB/Swiss-Prot:C0H405" /translation="MRPEEITEMIEQLRTGAINELRVQKEHFLDFRAVLSKQDDFKHF RGIAQQGGDVIFQYLEQPRS*" gene 1448013..1448207 /gene="ykzS" /locus_tag="BSU_13819" /old_locus_tag="BSU13819" downshifts 1448183 /Source="Nicolas_upshifts" /id="D766" /incds=0 /nref=6 /ntot=124 /MaxReadThrough="3.66738" /MaxDrop="3.03929" /score="5.82604583" /energy="-10.6" /TU="U1125" /idTUdmin="U1123" /TUdmin=682 /isTUend="FALSE" promotor_-10 complement(1448228..1448246) /Source="Nicolas_upshift_promotors" /id="U1126" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.987012987012987" /psig="0.987012987012987" /xcortree=1145 /SigmaFactorBS="tactttacattttatttacacctgttacagacagctGTAATA aaaggcttgtgttctgTCATATATGATAAAAAGGCttctcacgtatgagaaaccttca g" /listShort="S501, ykvS" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1448244) /Source="Nicolas_upshifts" /id="U1126" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.987012987012987" /psig="0.987012987012987" /xcortree=1145 /SigmaFactorBS="tactttacattttatttacacctgttacagacagctGTAATA aaaggcttgtgttctgTCATATATGATAAAAAGGCttctcacgtatgagaaaccttca g" /listShort="S501, ykvS" /GFF_Attribute="listLong" promotor_-35 complement(1448263..1448268) /Source="Nicolas_upshift_promotors" /id="U1126" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.987012987012987" /psig="0.987012987012987" /xcortree=1145 /SigmaFactorBS="tactttacattttatttacacctgttacagacagctGTAATA aaaggcttgtgttctgTCATATATGATAAAAAGGCttctcacgtatgagaaaccttca g" /listShort="S501, ykvS" /GFF_Attribute="listLong" /label="promotor_-35" CDS 1448506..1449132 /gene="ykvT" /locus_tag="BSU_13820" /old_locus_tag="BSU13820" /function="16.13: Shape" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2b: Function from indirect experimental evidences (e.g. phenotypes); PubMedId: 12177332, 12950927, 23199363; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="cell wall hydrolase related to spore cortex-lytic enzymes" /protein_id="NP_389265.1" /db_xref="EnsemblGenomes-Gn:BSU13820" /db_xref="EnsemblGenomes-Tr:CAB13255" /db_xref="GOA:O31685" /db_xref="InterPro:IPR011105" /db_xref="SubtiList:BG13322" /db_xref="UniProtKB/Swiss-Prot:O31685" /translation="MTTKFTALAVFLLCFMPAAKIEHTQASLLSAKKTKHEEAKWLTH IDRNTNESFPSLSADKDKKIKPIKLSAHTEKKEKDKPDKTNDEKETYTQSEKELLSRL VHAEAKGESYKGKVAVASVVLNRTEKKGFPDTIRGVIYQKNAFEPVANGSINQKPDKE SIEAAEEALSSKNRETDAIFFYNPKTASDNWIRSRKIVEKIGRHVFAV*" gene 1448506..1449132 /gene="ykvT" /locus_tag="BSU_13820" /old_locus_tag="BSU13820" downshifts 1449063 /Source="Nicolas_upshifts" /id="D767" /incds=1 /nref=1 /ntot=17 /MaxReadThrough="0.932830000000001" /MaxDrop="1.92264" /score="9.80914166" /energy="-11.9" /TU="NA" /idTUdmin="U1125" /TUdmin=44 /isTUend="FALSE" promotor_-35 1449189..1449194 /Source="Nicolas_upshift_promotors" /id="U1127" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=991 /SigmaFactorBS="gagacaatttgtctcagctgtgctttttttcatataaagagt aaaaatAAAATAatttttgaacttgtcTCATATGATGTTGGTAGTAcaagagacaagg a" /listShort="ykvU, stoA" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 1449201 /Source="Nicolas_upshifts" /id="U1127" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=991 /SigmaFactorBS="gagacaatttgtctcagctgtgctttttttcatataaagagt aaaaatAAAATAatttttgaacttgtcTCATATGATGTTGGTAGTAcaagagacaagg a" /listShort="ykvU, stoA" /GFF_Attribute="listLong" promotor_-10 1449210..1449228 /Source="Nicolas_upshift_promotors" /id="U1127" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=991 /SigmaFactorBS="gagacaatttgtctcagctgtgctttttttcatataaagagt aaaaatAAAATAatttttgaacttgtcTCATATGATGTTGGTAGTAcaagagacaagg a" /listShort="ykvU, stoA" /GFF_Attribute="listLong" /label="promotor_-10" CDS 1449250..1450587 /gene="ykvU" /locus_tag="BSU_13830" /old_locus_tag="BSU13830" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:15686839, 15849754, 16850406, 19648239" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15686839, 15849754, 16850406, 19648239; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="spore membrane protein involved in germination" /protein_id="NP_389266.1" /db_xref="EnsemblGenomes-Gn:BSU13830" /db_xref="EnsemblGenomes-Tr:CAB13256" /db_xref="GOA:O31686" /db_xref="InterPro:IPR002797" /db_xref="InterPro:IPR024923" /db_xref="SubtiList:BG13323" /db_xref="UniProtKB/Swiss-Prot:O31686" /translation="MNRFVKGIILLSIAAFFAECLEFVVNMILARELGEHGMGLYMSI LPTIFLIIVIASLELPISISKFIAESNPKLHESMLRHAFRMTAIFTAFSTAAASIALP FIPVFDTYHPFIKGIVIGLIPVVAFTSIARGYFMGVQKMGKIAIANVLKKIIQLLCLF LFFQWYSFELDMAVLISLFVLVVSDVVVLVYLYSQFIMARRALSGQQHIHLRGKDVRK RLLAVSIPTTGLRIFHAVVNAIEPFLVKGALLAAGVAGTAAIDQYGMLAGVAVTIGSF PAFIAHSLMVVMIPSISEAYALSQYDIVLKRLKQSIFITLGYGIPAVWVMFQFAGPLT HLFFHSPEAQYYLQLLWPYFLFHLFVMPLQACLIGMGFVKEAFYHNVWSHIVALSMMY VLGSMENLQMLGIILGMNTGMILLTSLHYATICKALKVSVFLTGGTRTPRIEG*" gene 1449250..1450587 /gene="ykvU" /locus_tag="BSU_13830" /old_locus_tag="BSU13830" CDS 1450638..1451135 /gene="stoA" /locus_tag="BSU_13840" /old_locus_tag="BSU13840" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:15292147, 15322369, 15342593, 19144642, 28383125" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15292147, 15322369, 15342593, 19144642, 28383125; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="spore-specific thiol-disulfide oxidoreductase (SpoVD maturation)" /protein_id="NP_389267.1" /db_xref="EnsemblGenomes-Gn:BSU13840" /db_xref="EnsemblGenomes-Tr:CAB13257" /db_xref="GOA:O31687" /db_xref="InterPro:IPR000866" /db_xref="InterPro:IPR013766" /db_xref="InterPro:IPR017937" /db_xref="InterPro:IPR036249" /db_xref="PDB:3ERW" /db_xref="SubtiList:BG13324" /db_xref="UniProtKB/Swiss-Prot:O31687" /translation="MLTKRLLTIYIMLLGLIAWFPGAAQAEEKQPAVPAVFLMKTIEG EDISIPNKGQKTILHFWTSWCPPCKKELPQFQSFYDAHPSDSVKLVTVNLVNSEQNQQ VVEDFIKANKLTFPIVLDSKGELMKEYHIITIPTSFLLNEKGEIEKTKIGPMTAEQLK EWTEE*" gene 1450638..1451135 /gene="stoA" /locus_tag="BSU_13840" /old_locus_tag="BSU13840" promotor_-35 1450984..1450990 /Source="Nicolas_upshift_promotors" /id="U1128" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=267 /SigmaFactorBS="agcaagtcgttgaagactttattaaagcaaacaagctgacgt ttcCGATTGTccttgactcaaaagGGGAATTGATGAAGGAGTAtcatatcatcacgat c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 1450999 /Source="Nicolas_upshifts" /id="U1128" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=267 /SigmaFactorBS="agcaagtcgttgaagactttattaaagcaaacaagctgacgt ttcCGATTGTccttgactcaaaagGGGAATTGATGAAGGAGTAtcatatcatcacgat c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 1451005..1451023 /Source="Nicolas_upshift_promotors" /id="U1128" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=267 /SigmaFactorBS="agcaagtcgttgaagactttattaaagcaaacaagctgacgt ttcCGATTGTccttgactcaaaagGGGAATTGATGAAGGAGTAtcatatcatcacgat c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" downshifts 1451109 /Source="Nicolas_upshifts" /id="D768" /incds=0 /nref=36 /ntot=164 /MaxReadThrough="1.89069" /MaxDrop="4.34947" /score="14.1388498" /energy="-11.3" /TU="NA" /idTUdmin="U1127" /TUdmin=0 /isTUend="TRUE" promotor_-35 1451230..1451236 /Source="Nicolas_upshift_promotors" /id="U1129" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.832167832167832" /psig=1 /xcortree=1532 /SigmaFactorBS="tattatcaaaaagaaattaaaataattataaTTGAAATtctc ttcgtgCGTGCTATAATAAAGGAAGAcatcaagaaataactgacgataaagctgcctt t" /listShort="S502, zosA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1451247..1451266 /Source="Nicolas_upshift_promotors" /id="U1129" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.832167832167832" /psig=1 /xcortree=1532 /SigmaFactorBS="tattatcaaaaagaaattaaaataattataaTTGAAATtctc ttcgtgCGTGCTATAATAAAGGAAGAcatcaagaaataactgacgataaagctgcctt t" /listShort="S502, zosA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1451259 /Source="Nicolas_upshifts" /id="U1129" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.832167832167832" /psig=1 /xcortree=1532 /SigmaFactorBS="tattatcaaaaagaaattaaaataattataaTTGAAATtctc ttcgtgCGTGCTATAATAAAGGAAGAcatcaagaaataactgacgataaagctgcctt t" /listShort="S502, zosA" /GFF_Attribute="listLong" S_feature 1451263..1451370 /Source="Nicolas_S_feature" /locus_tag="new_1451263_1451370" /HighExp="LBGstat, C90, Lbstat, BC, Cold, T0.30H, Etha, Lbtran, LBGtran, BI" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S502" CDS 1451371..1453284 /gene="pfeT" /locus_tag="BSU_13850" /old_locus_tag="BSU13850" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:12029044, 12180919, 15802251, 21813502, 26261021, 26566138" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12029044, 12180919, 15802251, 21813502, 26261021, 26566138; Product type t : transporter" /codon_start=1 /transl_table=11 /product="Fe(II) efflux transporter possibly involved in copper(II) uptake" /protein_id="NP_389268.1" /db_xref="EnsemblGenomes-Gn:BSU13850" /db_xref="EnsemblGenomes-Tr:CAB13258" /db_xref="GOA:O31688" /db_xref="InterPro:IPR001757" /db_xref="InterPro:IPR008250" /db_xref="InterPro:IPR018303" /db_xref="InterPro:IPR023214" /db_xref="InterPro:IPR023298" /db_xref="InterPro:IPR023299" /db_xref="InterPro:IPR027256" /db_xref="InterPro:IPR036412" /db_xref="SubtiList:BG13325" /db_xref="UniProtKB/Swiss-Prot:O31688" /translation="MNEQVIVQRDPHEPLKTDKREKNWAQHAELIAALVSGALILAGW LLSGYQVLSIILFLLAFVIGGFAKAKEGIEETLESKTLNVELLMIFAAIGSALIGYWA EGAILIFIFSLSGALETYTMNKSSRDLTSLMQLEPEEATLMVNGETKRVPVSDLQAGD MIVIKPGERVAADGIIESGSTSLDESALTGESMPVEKNTGDTVFTGTVNRNGSLTVRV TKANEDSLFRKIIKLVESAQNSVSPAQAFIERFENAYVKGVLIAVALLLFVPHFALGW SWSETFYRAMVFMVVASPCALVASIMPAALSLISNGARNGMLVKGSVFLEQLGSVQMI AFDKTGTVTKGQPAVETIRIAEGFSEAEVLEAVYAIETQSSHPLAQAITAYAESRGVN QSGYISIEETSGFGVMAEVSGAKWKVGKAGFIGEEMAAQFMKQTASDVIQSGHTIVFV KKDDQIAGCIALKDQIRPEAKEVMEELNRLGIKTAMLTGDHEDTAQAIAKEAGMTTVV AECLPDQKVNEIKRLKEEFGTIAMVGDGINDAPALKAADVGIAMGGGTDVALETADMV LMKNDLKKLVNMCRLSRKMNRIIKQNIVFSLAVICLLICANFLQAMELPFGVIGHEGS TILVILNGLRLLK*" gene 1451371..1453284 /gene="pfeT" /locus_tag="BSU_13850" /old_locus_tag="BSU13850" promotor_-10 complement(1451520..1451539) /Source="Nicolas_upshift_promotors" /id="U1130" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.984015984015984" /psig="0.984015984015984" /xcortree=1375 /SigmaFactorBS="gtttcttcgattccttccttcgctttagcaaatccgCCGATC ACAAaagccagcaagaAAAGTATTATGGATAATACCtgatatccggataagagccagc c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1451537) /Source="Nicolas_upshifts" /id="U1130" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.984015984015984" /psig="0.984015984015984" /xcortree=1375 /SigmaFactorBS="gtttcttcgattccttccttcgctttagcaaatccgCCGATC ACAAaagccagcaagaAAAGTATTATGGATAATACCtgatatccggataagagccagc c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(1451552..1451561) /Source="Nicolas_upshift_promotors" /id="U1130" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.984015984015984" /psig="0.984015984015984" /xcortree=1375 /SigmaFactorBS="gtttcttcgattccttccttcgctttagcaaatccgCCGATC ACAAaagccagcaagaAAAGTATTATGGATAATACCtgatatccggataagagccagc c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(1451688..1451707) /Source="Nicolas_upshift_promotors" /id="U1131" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=748 /SigmaFactorBS="gctgcattaaagacgttaaatctctgctgcttttattcatcg tgtaTGTTTCTaaagctccgcttaAGGAAAAAATAAATATTAAAatagcaccctctgc c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1451713) /Source="Nicolas_upshifts" /id="U1131" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=748 /SigmaFactorBS="gctgcattaaagacgttaaatctctgctgcttttattcatcg tgtaTGTTTCTaaagctccgcttaAGGAAAAAATAAATATTAAAatagcaccctctgc c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(1451721..1451727) /Source="Nicolas_upshift_promotors" /id="U1131" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=748 /SigmaFactorBS="gctgcattaaagacgttaaatctctgctgcttttattcatcg tgtaTGTTTCTaaagctccgcttaAGGAAAAAATAAATATTAAAatagcaccctctgc c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 1453265 /Source="Nicolas_upshifts" /id="D769" /incds=0 /nref=62 /ntot=148 /MaxReadThrough="2.05978" /MaxDrop="6.90668" /score="30.2111295" /energy="-18" /TU="NA" /idTUdmin="U1129" /TUdmin=0 /isTUend="TRUE" downshifts complement(1453341) /Source="Nicolas_upshifts" /id="D770" /incds=0 /nref=74 /ntot=208 /MaxReadThrough="0.83751" /MaxDrop="4.23141" /score="34.2342147" /energy="-18" /TU="NA" /idTUdmin="U1132" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(1453552..1453571) /Source="Nicolas_upshift_promotors" /id="U1132" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.684315684315684" /psig="0.999000999001" /xcortree=3126 /SigmaFactorBS="gcctttcacgacgccttcattttctaatgCATTTTATttcct gctcctctTCCTGTATACTGACAGTAACgttcaatcgcaggggggttgttccgtttgc t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1453561) /Source="Nicolas_upshifts" /id="U1132" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.684315684315684" /psig="0.999000999001" /xcortree=3126 /SigmaFactorBS="gcctttcacgacgccttcattttctaatgCATTTTATttcct gctcctctTCCTGTATACTGACAGTAACgttcaatcgcaggggggttgttccgtttgc t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(1453585..1453592) /Source="Nicolas_upshift_promotors" /id="U1132" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.684315684315684" /psig="0.999000999001" /xcortree=3126 /SigmaFactorBS="gcctttcacgacgccttcattttctaatgCATTTTATttcct gctcctctTCCTGTATACTGACAGTAACgttcaatcgcaggggggttgttccgtttgc t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" misc_feature 1453636..1453655 /Source="Nicolas_upshift_promotors" /id="U1133" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.434565434565435" /psig=1 /xcortree=1996 /SigmaFactorBS="taaaatgcattagaaaatgaaggcgtcgtgaaaggcaaacac cggtaaaaCCTGTTACAATGGAAGACAGaacaatgcattgcaaatggcagggaggaac a" /listShort="ykvY, S504, ykvZ, glcT, S505, ptsG, ptsH, ptsI" /listLong="splA, splB" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 1453646 /Source="Nicolas_upshifts" /id="U1133" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.434565434565435" /psig=1 /xcortree=1996 /SigmaFactorBS="taaaatgcattagaaaatgaaggcgtcgtgaaaggcaaacac cggtaaaaCCTGTTACAATGGAAGACAGaacaatgcattgcaaatggcagggaggaac a" /listShort="ykvY, S504, ykvZ, glcT, S505, ptsG, ptsH, ptsI" /listLong="splA, splB" CDS 1453691..1454782 /gene="papB" /locus_tag="BSU_13860" /old_locus_tag="BSU13860" /EC_number="3.4.13.-" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:7770058, 23144141" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7770058, 23144141; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="Xaa-Pro Xaa-Pro-Xaa di-tri-peptidase used in osmoprotection" /protein_id="NP_389269.1" /db_xref="EnsemblGenomes-Gn:BSU13860" /db_xref="EnsemblGenomes-Tr:CAB13259" /db_xref="GOA:O31689" /db_xref="InterPro:IPR000587" /db_xref="InterPro:IPR000994" /db_xref="InterPro:IPR001131" /db_xref="InterPro:IPR001714" /db_xref="InterPro:IPR029149" /db_xref="InterPro:IPR036005" /db_xref="SubtiList:BG13326" /db_xref="UniProtKB/Swiss-Prot:O31689" /translation="MNRIQRVSSWLKEAGHTAAFIHTKENVFYLTGFYTEPHERLMGL FIFQEEEPFFVCPGMEAGQARNAGWNHEIIGYADHENPWELIEKALKKRNISIHMLAV EKDSISLSRAEQLKHATGGAQFVSAEETLNQFRLIKDDNEIRLLKEAAKLADYGVEVG TAALREGISEVEVLAQIEYELKKKGIQGMSFSTMVLFGEKSGQPHGNPGTATLKKGDF VLFDLGVILDGYCSDITRTFAYKTINPKQEAIYETVLQAEKAAIEASKPGVRIGDLDL TARGIIEKAGYGDYFPHRLGHGLGISVHEYPSMSQANDTLLQEGMVYTIEPGIYVPEI GGVRIEDDVHVTKDGAVALTQYPKDLIIL*" gene 1453691..1454782 /gene="papB" /locus_tag="BSU_13860" /old_locus_tag="BSU13860" downshifts 1454431 /Source="Nicolas_upshifts" /id="D771" /incds=1 /nref=1 /ntot=1 /MaxReadThrough="6.10599" /MaxDrop="5.06339" /score="-5.18621526" /energy="-6.2" /TU="U1133" /idTUdmin="U1129" /TUdmin=1166 /isTUend="FALSE" downshifts 1454761 /Source="Nicolas_upshifts" /id="D772" /incds=0 /nref=2 /ntot=52 /MaxReadThrough="5.66039" /MaxDrop="2.56719" /score="-5.18621526" /energy="-6.2" /TU="U1133" /idTUdmin="U1129" /TUdmin=1496 /isTUend="FALSE" S_feature complement(1454795..1455013) /Source="Nicolas_S_feature" /locus_tag="new_1454795_1455013_c" /HighExp="B60, B36, C30, G135, LBGstat, S8, Lbstat, C90, Etha, S7" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.92748200000000003" /TUshortSig="SigA" /TUshortPSig="0.992" /TUlongSig="NA" /TUlongPSig="NA" /label="S503" S_feature 1454806..1455063 /Source="Nicolas_S_feature" /locus_tag="new_1454806_1455063" /HighExp="dia15, dia5, Etha, M0t90, M40t90, Lbstat, H2O2, G150, Mt0, Diami" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S504" promotor_-10 complement(1455000..1455019) /Source="Nicolas_upshift_promotors" /id="U1134" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.906093906093906" /psig="0.992007992007992" /xcortree=603 /SigmaFactorBS="tattagccatagattcccttctttctaaatcCCCTTGATctg gaatgcgtttcaTACAATATGATATGGACGTAccagatatctttttgtgtttttagct g" /listShort="S503" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1455013) /Source="Nicolas_upshifts" /id="U1134" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.906093906093906" /psig="0.992007992007992" /xcortree=603 /SigmaFactorBS="tattagccatagattcccttctttctaaatcCCCTTGATctg gaatgcgtttcaTACAATATGATATGGACGTAccagatatctttttgtgtttttagct g" /listShort="S503" /GFF_Attribute="listLong" promotor_-35 complement(1455035..1455042) /Source="Nicolas_upshift_promotors" /id="U1134" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.906093906093906" /psig="0.992007992007992" /xcortree=603 /SigmaFactorBS="tattagccatagattcccttctttctaaatcCCCTTGATctg gaatgcgtttcaTACAATATGATATGGACGTAccagatatctttttgtgtttttagct g" /listShort="S503" /GFF_Attribute="listLong" /label="promotor_-35" CDS 1455064..1456029 /gene="ykvZ" /locus_tag="BSU_13870" /old_locus_tag="BSU13870" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative transcriptional regulator (LacI family)" /protein_id="NP_389270.1" /db_xref="EnsemblGenomes-Gn:BSU13870" /db_xref="EnsemblGenomes-Tr:CAB13260" /db_xref="GOA:O31690" /db_xref="InterPro:IPR000843" /db_xref="InterPro:IPR001761" /db_xref="InterPro:IPR010982" /db_xref="InterPro:IPR028082" /db_xref="SubtiList:BG13327" /db_xref="UniProtKB/Swiss-Prot:O31690" /translation="MANIKDIAEKAGVSVTTVSRVINNHPYVSEDKRKRVFEAMESLE YTRNIHAVHLSKGFSNMIGVVLPTVNLPYFAELIAGIADAAAESGVHLSLFQTNYEVQ KEIFALSQLKQRQVDGLIFCSKALADEKLMEWEGPILLCQNSDNARFPTISIPHQEAF RNGLDYLIAKGHKKIAICLARKKGMNSHFRIKAYKEALEEIGEAFREDWVIEKAITIN DGKALFHKWNTWKEKPTAIFVANDQVSAGLFLEAKNQRVSVPDELAILSVDNHEISQA LGITTIDIQTREMGKQAFAILEKRIQGQPIERKVLDYRLIERSTV*" gene 1455064..1456029 /gene="ykvZ" /locus_tag="BSU_13870" /old_locus_tag="BSU13870" promotor_-35 1456047..1456054 /Source="Nicolas_upshift_promotors" /id="U1135" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.555444555444555" /psig="0.988011988011988" /xcortree=2551 /SigmaFactorBS="actgtttagtgaatgcattgaaaaaaGGTTTGACgtgcattc tgttcgTTATGTACGATATGAGGTATtgaatgacaaaggagctgaggatcgtgaatgg g" /listShort="glcT, S505" /listLong="ptsG, ptsH, ptsI, splA, splB" /label="promotor_-35" promotor_-10 1456069..1456088 /Source="Nicolas_upshift_promotors" /id="U1135" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.555444555444555" /psig="0.988011988011988" /xcortree=2551 /SigmaFactorBS="actgtttagtgaatgcattgaaaaaaGGTTTGACgtgcattc tgttcgTTATGTACGATATGAGGTATtgaatgacaaaggagctgaggatcgtgaatgg g" /listShort="glcT, S505" /listLong="ptsG, ptsH, ptsI, splA, splB" /label="promotor_-10" upshifts 1456081 /Source="Nicolas_upshifts" /id="U1135" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.555444555444555" /psig="0.988011988011988" /xcortree=2551 /SigmaFactorBS="actgtttagtgaatgcattgaaaaaaGGTTTGACgtgcattc tgttcgTTATGTACGATATGAGGTATtgaatgacaaaggagctgaggatcgtgaatgg g" /listShort="glcT, S505" /listLong="ptsG, ptsH, ptsI, splA, splB" CDS 1456092..1456958 /gene="glcT" /locus_tag="BSU_13880" /old_locus_tag="BSU13880" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:10974121, 14527945, 15155854, 17074746, 22750856" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10974121, 14527945, 15155854, 17074746, 22750856; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional antiterminator (BglG family)" /protein_id="NP_389271.2" /db_xref="EnsemblGenomes-Gn:BSU13880" /db_xref="EnsemblGenomes-Tr:CAB13261" /db_xref="GOA:O31691" /db_xref="InterPro:IPR001550" /db_xref="InterPro:IPR004341" /db_xref="InterPro:IPR011608" /db_xref="InterPro:IPR036634" /db_xref="InterPro:IPR036650" /db_xref="PDB:3GWH" /db_xref="PDB:3RIO" /db_xref="PDB:3UFE" /db_xref="SubtiList:BG12593" /db_xref="UniProtKB/Swiss-Prot:O31691" /translation="MTKELRIVNGSFTVKKVLNNNVLIASHHKYSEVVLIGKGIGFGK KQDDVIEDKGYDKMFILKDEKEQKQFKKLLDYVDEKLVDISNDVIYHISNRTNHSLNE HIHIALTDHIAFAIKRQQQGFDMKNPFLMETQSLYPEEYQIAKEVIDMINEKAGLCLP EGEIGFIALHIHSALTNRPLSEVNQHSQLMAQLVEVIEDSFQMKVNKESVNYLRLIRH IRFTIERIKKEEPTKEPEKLMLLLKNEYPLCYNTAWKLIKILQQTLKKPVHEAEAVYL TLHLYRLTNKIS*" gene 1456092..1456958 /gene="glcT" /locus_tag="BSU_13880" /old_locus_tag="BSU13880" promotor_-35 1456813..1456817 /Source="Nicolas_upshift_promotors" /id="U1136" /multdbtbs="SigA" /comp="M16" /sig="SigA" /pcomp="0.925074925074925" /psig=1 /xcortree=2686 /SigmaFactorBS="ccgactaaagaaccagaaaaattaatgttgtTATTGaaaaat gaatatccgcTATGCTACAATACAGCTTGGaaattgattaaaatcttgcagcaaacat t" /listShort="S505, ptsG, ptsH, ptsI, splA, splB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1456834..1456853 /Source="Nicolas_upshift_promotors" /id="U1136" /multdbtbs="SigA" /comp="M16" /sig="SigA" /pcomp="0.925074925074925" /psig=1 /xcortree=2686 /SigmaFactorBS="ccgactaaagaaccagaaaaattaatgttgtTATTGaaaaat gaatatccgcTATGCTACAATACAGCTTGGaaattgattaaaatcttgcagcaaacat t" /listShort="S505, ptsG, ptsH, ptsI, splA, splB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1456842 /Source="Nicolas_upshifts" /id="U1136" /multdbtbs="SigA" /comp="M16" /sig="SigA" /pcomp="0.925074925074925" /psig=1 /xcortree=2686 /SigmaFactorBS="ccgactaaagaaccagaaaaattaatgttgtTATTGaaaaat gaatatccgcTATGCTACAATACAGCTTGGaaattgattaaaatcttgcagcaaacat t" /listShort="S505, ptsG, ptsH, ptsI, splA, splB" /GFF_Attribute="listLong" downshifts 1456960 /Source="Nicolas_upshifts" /id="D773" /incds=0 /nref=1 /ntot=30 /MaxReadThrough="9.01653" /MaxDrop="3.09921" /score="-5.18621526" /energy="-6.2" /TU="U1133,U1135,U1136" /idTUdmin="U1135" /TUdmin="-220" /isTUend="FALSE" misc_RNA 1457005..1457156 /gene="gswA" /locus_tag="BSU_misc_RNA_88" /product="riboswitch regulating ptsGHI expression via GlcTbinding" /experiment="publication(s) with functional evidences, PMID:15155854, 22750856" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15155854, 22750856; Product type n: RNA" S_feature 1457005..1457156 /Source="Nicolas_S_feature" /locus_tag="new_1457005_1457156" /HighExp="LBGexp, G150, C30, G135, G180, MG 90, dia0, Lbexp, dia15, GM-0.1" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA, SigA" /TUshortPSig="1, 0.988, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S505" gene 1457005..1457156 /gene="gswA" /locus_tag="BSU_misc_RNA_88" promotor_-35 1457134..1457140 /Source="Nicolas_upshift_promotors" /id="U1137" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.752247752247752" /psig="0.752247752247752" /xcortree=1446 /SigmaFactorBS="cggttaaactggaagacttacgcctgtgaattcgttGTCATG AtttttagctgtaaGGTCAGACTAGTaaaaagaggaggtcaattcttatgtttaaagc a" /listShort="ptsG, ptsH, ptsI" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1457154..1457165 /Source="Nicolas_upshift_promotors" /id="U1137" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.752247752247752" /psig="0.752247752247752" /xcortree=1446 /SigmaFactorBS="cggttaaactggaagacttacgcctgtgaattcgttGTCATG AtttttagctgtaaGGTCAGACTAGTaaaaagaggaggtcaattcttatgtttaaagc a" /listShort="ptsG, ptsH, ptsI" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1457158 /Source="Nicolas_upshifts" /id="U1137" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.752247752247752" /psig="0.752247752247752" /xcortree=1446 /SigmaFactorBS="cggttaaactggaagacttacgcctgtgaattcgttGTCATG AtttttagctgtaaGGTCAGACTAGTaaaaagaggaggtcaattcttatgtttaaagc a" /listShort="ptsG, ptsH, ptsI" /GFF_Attribute="listLong" CDS 1457187..1459286 /gene="ptsG" /locus_tag="BSU_13890" /old_locus_tag="BSU13890" /EC_number="2.7.1.199" /function="16.1: Circulate" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:1447219, 8418852, 8432747, 9593197, 14527945, 15849754, 16850406, 22846916" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1447219, 8418852, 8432747, 9593197, 14527945, 15849754, 16850406, 22846916; Product type t: transporter" /codon_start=1 /transl_table=11 /product="phosphotransferase system (PTS) glucose-specificenzyme IICBA component" /protein_id="NP_389272.1" /db_xref="EnsemblGenomes-Gn:BSU13890" /db_xref="EnsemblGenomes-Tr:CAB13262" /db_xref="GOA:P20166" /db_xref="InterPro:IPR001127" /db_xref="InterPro:IPR001996" /db_xref="InterPro:IPR003352" /db_xref="InterPro:IPR004719" /db_xref="InterPro:IPR011055" /db_xref="InterPro:IPR011299" /db_xref="InterPro:IPR013013" /db_xref="InterPro:IPR018113" /db_xref="InterPro:IPR036878" /db_xref="PDB:1AX3" /db_xref="PDB:1GPR" /db_xref="SubtiList:BG10198" /db_xref="UniProtKB/Swiss-Prot:P20166" /translation="MFKALFGVLQKIGRALMLPVAILPAAGILLAIGNAMQNKDMIQV LHFLSNDNVQLVAGVMESAGQIVFDNLPLLFAVGVAIGLANGDGVAGIAAIIGYLVMN VSMSAVLLANGTIPSDSVERAKFFTENHPAYVNMLGIPTLATGVFGGIIVGVLAALLF NRFYTIELPQYLGFFAGKRFVPIVTSISALILGLIMLVIWPPIQHGLNAFSTGLVEAN PTLAAFIFGVIERSLIPFGLHHIFYSPFWYEFFSYKSAAGEIIRGDQRIFMAQIKDGV QLTAGTFMTGKYPFMMFGLPAAALAIYHEAKPQNKKLVAGIMGSAALTSFLTGITEPL EFSFLFVAPVLFAIHCLFAGLSFMVMQLLNVKIGMTFSGGLIDYFLFGILPNRTAWWL VIPVGLGLAVIYYFGFRFAIRKFNLKTPGREDAAEETAAPGKTGEAGDLPYEILQAMG DQENIKHLDACITRLRVTVNDQKKVDKDRLKQLGASGVLEVGNNIQAIFGPRSDGLKT QMQDIIAGRKPRPEPKTSAQEEVGQQVEEVIAEPLQNEIGEEVFVSPITGEIHPITDV PDQVFSGKMMGDGFAILPSEGIVVSPVRGKILNVFPTKHAIGLQSDGGREILIHFGID TVSLKGEGFTSFVSEGDRVEPGQKLLEVDLDAVKPNVPSLMTPIVFTNLAEGETVSIK ASGSVNREQEDIVKIEK*" gene 1457187..1459286 /gene="ptsG" /locus_tag="BSU_13890" /old_locus_tag="BSU13890" promotor_-35 1459304..1459308 /Source="Nicolas_upshift_promotors" /id="U1138" /multdbtbs="SigA" /comp="M16" /sig="SigA" /pcomp="0.903096903096903" /psig=1 /xcortree=2687 /SigmaFactorBS="attgaaaaataagggtgttagtacgccgtGCTTGtcagatga caagtacGGTTGTATGATATAATATTGtgaagtaataaagctttaagttaaaaggaga a" /listShort="ptsH, ptsI, splA, splB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1459324..1459343 /Source="Nicolas_upshift_promotors" /id="U1138" /multdbtbs="SigA" /comp="M16" /sig="SigA" /pcomp="0.903096903096903" /psig=1 /xcortree=2687 /SigmaFactorBS="attgaaaaataagggtgttagtacgccgtGCTTGtcagatga caagtacGGTTGTATGATATAATATTGtgaagtaataaagctttaagttaaaaggaga a" /listShort="ptsH, ptsI, splA, splB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1459335 /Source="Nicolas_upshifts" /id="U1138" /multdbtbs="SigA" /comp="M16" /sig="SigA" /pcomp="0.903096903096903" /psig=1 /xcortree=2687 /SigmaFactorBS="attgaaaaataagggtgttagtacgccgtGCTTGtcagatga caagtacGGTTGTATGATATAATATTGtgaagtaataaagctttaagttaaaaggaga a" /listShort="ptsH, ptsI, splA, splB" /GFF_Attribute="listLong" CDS 1459384..1459650 /gene="ptsH" /locus_tag="BSU_13900" /old_locus_tag="BSU13900" /function="16.3: Control" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:10217795, 12411438, 14527945, 15126459, 16267306, 17085448, 17142398, 17726680, 20487301, 25355936" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10217795, 12411438, 14527945, 15126459, 16267306, 17085448, 17142398, 17726680, 20487301, 25355936; Product type f: factor" /codon_start=1 /transl_table=11 /product="histidine-containing phosphocarrier protein of the phosphotransferase system (PTS) (HPr protein)" /protein_id="NP_389273.1" /db_xref="EnsemblGenomes-Gn:BSU13900" /db_xref="EnsemblGenomes-Tr:CAB13263" /db_xref="GOA:P08877" /db_xref="InterPro:IPR000032" /db_xref="InterPro:IPR001020" /db_xref="InterPro:IPR002114" /db_xref="InterPro:IPR035895" /db_xref="PDB:1JEM" /db_xref="PDB:1KKL" /db_xref="PDB:1KKM" /db_xref="PDB:1SPH" /db_xref="PDB:2FEP" /db_xref="PDB:2HID" /db_xref="PDB:2HPR" /db_xref="PDB:3OQM" /db_xref="PDB:3OQN" /db_xref="PDB:3OQO" /db_xref="SubtiList:BG10200" /db_xref="UniProtKB/Swiss-Prot:P08877" /translation="MAQKTFKVTADSGIHARPATVLVQTASKYDADVNLEYNGKTVNL KSIMGVMSLGIAKGAEITISASGADENDALNALEETMKSEGLGE*" gene 1459384..1459650 /gene="ptsH" /locus_tag="BSU_13900" /old_locus_tag="BSU13900" CDS 1459650..1461362 /gene="ptsI" /locus_tag="BSU_13910" /old_locus_tag="BSU13910" /EC_number="2.7.3.9" /function="16.1: Circulate" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:3106335, 11902727, 15155854, 15670601, 25355936, 26159071" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 3106335, 11902727, 15155854, 15670601, 25355936, 26159071; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="phosphotransferase system (PTS) enzyme I" /protein_id="NP_389274.2" /db_xref="EnsemblGenomes-Gn:BSU13910" /db_xref="EnsemblGenomes-Tr:CAB13264" /db_xref="GOA:P08838" /db_xref="InterPro:IPR000121" /db_xref="InterPro:IPR006318" /db_xref="InterPro:IPR008279" /db_xref="InterPro:IPR008731" /db_xref="InterPro:IPR015813" /db_xref="InterPro:IPR018274" /db_xref="InterPro:IPR023151" /db_xref="InterPro:IPR024692" /db_xref="InterPro:IPR036618" /db_xref="SubtiList:BG10201" /db_xref="UniProtKB/Swiss-Prot:P08838" /translation="MQELKGIGASAGIAIAKAYRLEEPDLTVEKKNISDSEAEVSRFD EAIARSKEELEKIKEHALKELGQDKADIFSAHLLVLSDPELLNPVKEKISTDSVNAEF ALKETSSMFVTMFESMDNEYMKERAADIRDVTKRVTGHLLGVEIPNPSMISEEVIIVA EDLTPSDTAQLNREFVKGFTTDIGGRTSHSAIMARSLEIPAVVGTKAATGTIQNGVTV IVDGINGDVIIDPSAETVKEYEEKHNAYLAQKAEWAKLVNEPTVSKDGHHVELAANIG TPDDVKGVLENGGEAVGLYRTEFLYMGRDQLPTEDEQFDAYKTVLERMEGKSVVVRTL DIGGDKELPYLQLPKEMNPFLGYRAIRLCLEEQEIFRTQLRALLRASTYGNLKIMFPM IATVNEFKEAKAILLEEKEKLVKAGQAVSDDIEVGMMVEIPSTAVIADQFAKEVDFFS IGTNDLIQYTMAADRMNERVSYLYQPYNPAILRLITLVIEAAHKEGKWVGMCGEMAGD EIAIPILLGLGLDEFSMSATSILPARTQISKLSKQEAESFKEKILSMSTTEEVVAFVK ETFK*" gene 1459650..1461362 /gene="ptsI" /locus_tag="BSU_13910" /old_locus_tag="BSU13910" downshifts 1461349 /Source="Nicolas_upshifts" /id="D774" /incds=0 /nref=116 /ntot=277 /MaxReadThrough="5.0255" /MaxDrop="5.64321" /score="21.2608168" /energy="-12.3" /TU="U1136,U1138" /idTUdmin="U1133" /TUdmin=11 /isTUend="TRUE" promotor_-35 1461402..1461408 /Source="Nicolas_upshift_promotors" /id="U1139" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=850 /SigmaFactorBS="acaaaaaccagacggcctccggcctgtctggtttttTTCATA AgtaagggtatagaaGGACACAATAACatggctaggagggatagtatgtcaaaccaat t" /listShort="splA, splB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1461423..1461434 /Source="Nicolas_upshift_promotors" /id="U1139" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=850 /SigmaFactorBS="acaaaaaccagacggcctccggcctgtctggtttttTTCATA AgtaagggtatagaaGGACACAATAACatggctaggagggatagtatgtcaaaccaat t" /listShort="splA, splB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1461426 /Source="Nicolas_upshifts" /id="U1139" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=850 /SigmaFactorBS="acaaaaaccagacggcctccggcctgtctggtttttTTCATA AgtaagggtatagaaGGACACAATAACatggctaggagggatagtatgtcaaaccaat t" /listShort="splA, splB" /GFF_Attribute="listLong" CDS 1461453..1461692 /gene="splA" /locus_tag="BSU_13920" /old_locus_tag="BSU13920" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:9009064, 9323362, 10629212" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9009064, 9323362, 10629212; Product type r: regulator" /codon_start=1 /transl_table=11 /product="TRAP-like transcriptional negative regulator of spore photoproduct lyase" /protein_id="NP_389275.1" /db_xref="EnsemblGenomes-Gn:BSU13920" /db_xref="EnsemblGenomes-Tr:CAB13265" /db_xref="GOA:P37955" /db_xref="InterPro:IPR022608" /db_xref="SubtiList:BG10202" /db_xref="UniProtKB/Swiss-Prot:P37955" /translation="MSNQFNAGDTVYVIYRNPHAANVAHIKEAEIVHHPYHEGELSLF IYETYHPFAEDDAVFASYEEAKSLYKELFDIDPYE*" gene 1461453..1461692 /gene="splA" /locus_tag="BSU_13920" /old_locus_tag="BSU13920" S_feature complement(1461473..1462812) /Source="Nicolas_S_feature" /locus_tag="new_1461473_1462812_c" /HighExp="T4.0H, T3.30H, T3.0H, S3, S1, T2.0H, T2.30H, S2, T5.0H, S4" /AntisenseName="splB" /AntisenseCor="-0.193138593783996" /AntisenseRegPval="-2.8" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S506" CDS 1461770..1462798 /gene="splB" /locus_tag="BSU_13930" /old_locus_tag="BSU13930" /EC_number="4.1.99.14" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:9733691, 10629212, 11053385, 11470912, 16829680, 16829676, 17293412, 18055591, 22197590, 22961846, 23607538, 24598744, 28027411" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9733691, 10629212, 11053385, 11470912, 16829680, 16829676, 17293412, 18055591, 22197590, 22961846, 23607538, 24598744, 28027411; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="spore photoproduct (thymine dimer) lyase" /protein_id="NP_389276.1" /db_xref="EnsemblGenomes-Gn:BSU13930" /db_xref="EnsemblGenomes-Tr:CAB13266" /db_xref="GOA:P37956" /db_xref="InterPro:IPR007197" /db_xref="InterPro:IPR013785" /db_xref="InterPro:IPR023897" /db_xref="InterPro:IPR034560" /db_xref="SubtiList:BG10203" /db_xref="UniProtKB/Swiss-Prot:P37956" /translation="MQNPFVPQLVYIEPRALEYPLGQELQDKFENMGIEIRETTSHNQ VRNIPGKNHLQQYRNAKSTLVIGVRKTLKFDSSKPSAEYAIPFATGCMGHCHYCYLQT TMGSKPYIRTYVNVEEILDQADKYMKERAPEFTRFEASCTSDIVGIDHLTHTLKRAIE HFGQSDLGKLRFVTKFHHVDHLLDAKHNGKTRFRFSINADYVIKNFEPGTSPLDKRIE AAVKVAKAGYPLGFIVAPIYIHEGWEEGYRHLFEKLDAALPQDVRHDITFELIQHRFT KPAKRVIEKNYPKTKLELDEEKRRYKWGRYGIGKYIYQKDEEHALREALESYIDTFFP NAKIEYFT*" gene 1461770..1462798 /gene="splB" /locus_tag="BSU_13930" /old_locus_tag="BSU13930" downshifts 1462768 /Source="Nicolas_upshifts" /id="D775" /incds=0 /nref=5 /ntot=113 /MaxReadThrough="0.352" /MaxDrop="3.95383" /score="15.9223136" /energy="-13.2" /TU="NA" /idTUdmin="U1136" /TUdmin=0 /isTUend="TRUE" CDS complement(1462813..1463493) /gene="ykwB" /locus_tag="BSU_13940" /old_locus_tag="BSU13940" /function="18.1: Enzymes of unknown specificity" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative acetyltransferase / amidohydrolase" /protein_id="NP_389277.2" /db_xref="EnsemblGenomes-Gn:BSU13940" /db_xref="EnsemblGenomes-Tr:CAB13267" /db_xref="GOA:Q796K9" /db_xref="InterPro:IPR000182" /db_xref="InterPro:IPR016181" /db_xref="SubtiList:BG12252" /db_xref="UniProtKB/Swiss-Prot:Q796K9" /translation="MIILKQMYVHDGRKFEALTIRNYTETDIERLISLQEECFPPPFP QELLWSEDQLASHIKTFPEGALCALINGRIIGSMTALIVQFEPDSPDHTWAQATDNGS IKNHEPHGNTLYVVDISVSPHYRKLGIGKWLMNTMYELTVDKRLERLLGGGRIPLYYK YAHEISAVQYVEDVMEGRKNDPVLSFLLRCGRSPIRVVSNYLEDKESLNYGVLMEWKN VFYKKASC*" gene complement(1462813..1463493) /gene="ykwB" /locus_tag="BSU_13940" /old_locus_tag="BSU13940" promotor_-10 complement(1463503..1463522) /Source="Nicolas_upshift_promotors" /id="U1140" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.99100899100899" /psig=1 /xcortree=2873 /SigmaFactorBS="aaaatgaataatcaaaaaataaattataagaaaatcggaata TATTTACTgaaaattcaatcttCGTTATAATGAAACAACATAaggagagtgatgatca t" /listShort="ykwB, S506" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1463526) /Source="Nicolas_upshifts" /id="U1140" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.99100899100899" /psig=1 /xcortree=2873 /SigmaFactorBS="aaaatgaataatcaaaaaataaattataagaaaatcggaata TATTTACTgaaaattcaatcttCGTTATAATGAAACAACATAaggagagtgatgatca t" /listShort="ykwB, S506" /GFF_Attribute="listLong" promotor_-35 complement(1463537..1463544) /Source="Nicolas_upshift_promotors" /id="U1140" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.99100899100899" /psig=1 /xcortree=2873 /SigmaFactorBS="aaaatgaataatcaaaaaataaattataagaaaatcggaata TATTTACTgaaaattcaatcttCGTTATAATGAAACAACATAaggagagtgatgatca t" /listShort="ykwB, S506" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1463578..1463585 /Source="Nicolas_upshift_promotors" /id="U1141" /multdbtbs="SigD" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2802 /SigmaFactorBS="tattccgattttcttataatttattttttgattATTCATTTt tcaaacgaaaggGCCGATATAGAAATTAGGAggggattggtttgtttaaaaaacttca c" /listShort="mcpC" /listLong="ykwC" /label="promotor_-35" promotor_-10 1463599..1463617 /Source="Nicolas_upshift_promotors" /id="U1141" /multdbtbs="SigD" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2802 /SigmaFactorBS="tattccgattttcttataatttattttttgattATTCATTTt tcaaacgaaaggGCCGATATAGAAATTAGGAggggattggtttgtttaaaaaacttca c" /listShort="mcpC" /listLong="ykwC" /label="promotor_-10" upshifts 1463605 /Source="Nicolas_upshifts" /id="U1141" /multdbtbs="SigD" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2802 /SigmaFactorBS="tattccgattttcttataatttattttttgattATTCATTTt tcaaacgaaaggGCCGATATAGAAATTAGGAggggattggtttgtttaaaaaacttca c" /listShort="mcpC" /listLong="ykwC" CDS 1463628..1465595 /gene="mcpC" /locus_tag="BSU_13950" /old_locus_tag="BSU13950" /function="16.12: Sense" /experiment="publication(s) with functional evidences, PMID:9721285, 11722727, 12603740, 15317802, 23038252, 27899502" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9721285, 11722727, 12603740, 15317802, 23038252, 27899502; Product type rc : receptor" /codon_start=1 /transl_table=11 /product="methyl-accepting chemotaxis protein" /protein_id="NP_389278.2" /db_xref="EnsemblGenomes-Gn:BSU13950" /db_xref="EnsemblGenomes-Tr:CAB13268" /db_xref="GOA:P54576" /db_xref="InterPro:IPR003660" /db_xref="InterPro:IPR004089" /db_xref="InterPro:IPR029151" /db_xref="InterPro:IPR033479" /db_xref="SubtiList:BG11533" /db_xref="UniProtKB/Swiss-Prot:P54576" /translation="MFKKLHMKIAVFVSIMLIITVVLLMLSSYLTLKPMITEDGKNTT QNVTQSLEQNIELQLKSYAISLSRLANGELTHTFVTKPSKEASRLFHDDIKQIKDNDD YVAMAYIGTAKKEMFTYPKADFAEDYDPTSRPWYKLAAETPDQVVWTEPYKDVVTGDM IVTASKAILDRQKVIGVASYDLKLSAIQSMVNKQKVPYKGFAFLADASGNLLAHPSNQ GKNISKDQTLQTIASEKKGIQDVNGKMVVYQTIGETGWKVGTQFDTDQLMWISDKMNR ANLWISLIALIITIILSYFLAKTITGPIQQLIVKTKAVSAGDLTVRAESKSKDEVGIL TRDFNLMVENMKEMVEQVRLSSGKVSDTSEQLTAVAAETNETSGQIAKAIEEVAAGAS EQASEVETINEKSESLSTKIRQIAEEAGGIKERSKSSEDASYKGLDALGQLLMKSNEA NMETKKVETMLLDLENQTKNIEEVVTAISNISDQTNLLALNASIEAARAGESGRGFAV VADEVRKLAEQSALSTKHISETVKLIQLETKEASHAMVEASRMNDEQNSAIHETGEVL NTITAEMQSLVQGIDHIYAEIQRMSEEQLAISEAIQSISAISQESAAAAEEVNASTDE QLVTLDKVKHSTETLKHASQELMNTIAKFTL*" gene 1463628..1465595 /gene="mcpC" /locus_tag="BSU_13950" /old_locus_tag="BSU13950" misc_feature complement(1464068..1464083) /Source="Nicolas_upshift_promotors" /id="U1142" /multdbtbs="-" /comp="M6" /sig="Sig-" /pcomp="0.518481518481518" /psig="0.367632367632368" /xcortree=380 /SigmaFactorBS="cctgtctaagatcgctttcgatgcagtaacaatcatgtctcc tgtcacgacatctttATAAGGTTCCGTCCAAacaacttgatccggggtttcagctgca a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(1464080) /Source="Nicolas_upshifts" /id="U1142" /multdbtbs="-" /comp="M6" /sig="Sig-" /pcomp="0.518481518481518" /psig="0.367632367632368" /xcortree=380 /SigmaFactorBS="cctgtctaagatcgctttcgatgcagtaacaatcatgtctcc tgtcacgacatctttATAAGGTTCCGTCCAAacaacttgatccggggtttcagctgca a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" downshifts 1465566 /Source="Nicolas_upshifts" /id="D776" /incds=0 /nref=134 /ntot=209 /MaxReadThrough="3.05506" /MaxDrop="5.75836" /score="24.6367658" /energy="-12.1" /TU="U1141" /idTUdmin="U1141" /TUdmin="-89" /isTUend="FALSE" promotor_-35 1465639..1465641 /Source="Nicolas_upshift_promotors" /id="U1143" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.762237762237762" /psig=1 /xcortree=2290 /SigmaFactorBS="ccccaaacatcatttgttttggggattttttaTTTtataaga tgaatagaTATGGTAGTCTAGAAAATGAaggaaaaatgataaattttaactaaaatct a" /listShort="ykwC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1465657..1465676 /Source="Nicolas_upshift_promotors" /id="U1143" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.762237762237762" /psig=1 /xcortree=2290 /SigmaFactorBS="ccccaaacatcatttgttttggggattttttaTTTtataaga tgaatagaTATGGTAGTCTAGAAAATGAaggaaaaatgataaattttaactaaaatct a" /listShort="ykwC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1465667 /Source="Nicolas_upshifts" /id="U1143" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.762237762237762" /psig=1 /xcortree=2290 /SigmaFactorBS="ccccaaacatcatttgttttggggattttttaTTTtataaga tgaatagaTATGGTAGTCTAGAAAATGAaggaaaaatgataaattttaactaaaatct a" /listShort="ykwC" /GFF_Attribute="listLong" downshifts complement(1465709) /Source="Nicolas_upshifts" /id="D777" /incds=0 /nref=1 /ntot=91 /MaxReadThrough="2.29647" /MaxDrop="4.49503" /score="37.1302416" /energy="-14.5" /TU="NA" /idTUdmin="U1144" /TUdmin=946 /isTUend="FALSE" CDS 1465733..1466599 /gene="ohaC" /locus_tag="BSU_13960" /old_locus_tag="BSU13960" /EC_number="1.1.1.60" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:20941576, 24390483" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 20941576, 24390483; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="beta-hydroxyacid dehydrogenase (acts on 3-hydroxypropionate with NADP)" /protein_id="NP_389279.1" /db_xref="EnsemblGenomes-Gn:BSU13960" /db_xref="EnsemblGenomes-Tr:CAB13269" /db_xref="GOA:O34948" /db_xref="InterPro:IPR002204" /db_xref="InterPro:IPR006115" /db_xref="InterPro:IPR008927" /db_xref="InterPro:IPR013328" /db_xref="InterPro:IPR015815" /db_xref="InterPro:IPR029154" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG13328" /db_xref="UniProtKB/Swiss-Prot:O34948" /translation="MKKTIGFIGLGVMGKSMASHILNDGHPVLVYTRTKEKAESILQK GAIWKDTVKDLSKEADVIITMVGYPSDVEEVYFGSNGIIENAKEGAYLIDMTTSKPSL AKKIAEAAKEKALFALDAPVSGGDIGAQNGTLAIMVGGEKEAFEACMPIFSLMGENIQ YQGPAGSGQHTKMCNQIAIAAGMIGVAEAMAYAQKSGLEPENVLKSITTGAAGSWSLS NLAPRMLQGNFEPGFYVKHFIKDMGIALEEAELMGEEMPGLSLAKSLYDKLAAQGEEN SGTQSIYKLWVK*" gene 1465733..1466599 /gene="ohaC" /locus_tag="BSU_13960" /old_locus_tag="BSU13960" downshifts 1466579 /Source="Nicolas_upshifts" /id="D778" /incds=0 /nref=239 /ntot=266 /MaxReadThrough="2.14032" /MaxDrop="8.18847" /score="41.1703019" /energy="-14.5" /TU="NA" /idTUdmin="U1143" /TUdmin=0 /isTUend="TRUE" CDS complement(1466638..1467411) /gene="ykwD" /locus_tag="BSU_13970" /old_locus_tag="BSU13970" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_389280.2" /db_xref="EnsemblGenomes-Gn:BSU13970" /db_xref="EnsemblGenomes-Tr:CAB13270" /db_xref="InterPro:IPR014044" /db_xref="InterPro:IPR014258" /db_xref="InterPro:IPR035940" /db_xref="SubtiList:BG13329" /db_xref="UniProtKB/Swiss-Prot:O31398" /translation="MKKAFILSAAAAVGLFTFGGVQQASAKELSCQPVVTVKTGNTVQ NMSLNDAVKKLHINTNIKTLNAANEKEMKQLLQKHAKQSNVKVQDVQKTETAKPAQKT TEKAAADQNTASKAPATAEKTNTTTSAPSSVSAYEKKVVELTNAERQKQGLKPLQIDE TLSKSARAKSQDMKDKNYFDHQSPTYGSPFDMMKSFGISYKTAGENIAKGQKTPEEVV KAWMNSEGHRKNILNPNFTHIGVGYVESGSIWTQQFIGK*" gene complement(1466638..1467411) /gene="ykwD" /locus_tag="BSU_13970" /old_locus_tag="BSU13970" downshifts complement(1466655) /Source="Nicolas_upshifts" /id="D779" /incds=0 /nref=31 /ntot=168 /MaxReadThrough="1.32532" /MaxDrop="5.28625" /score="37.1302416" /energy="-14.5" /TU="NA" /idTUdmin="U1144" /TUdmin=0 /isTUend="TRUE" misc_feature complement(1467443..1467462) /Source="Nicolas_upshift_promotors" /id="U1144" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.711288711288711" /psig="0.994005994005994" /xcortree=2987 /SigmaFactorBS="acaatctctatttgtcaaaggaaagtgctggaatctttatga caaaaaagcTATGTTATGATTTTTCTGTAgaaacaaacaactctaggaggttacgaac t" /listShort="ykwD" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(1467453) /Source="Nicolas_upshifts" /id="U1144" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.711288711288711" /psig="0.994005994005994" /xcortree=2987 /SigmaFactorBS="acaatctctatttgtcaaaggaaagtgctggaatctttatga caaaaaagcTATGTTATGATTTTTCTGTAgaaacaaacaactctaggaggttacgaac t" /listShort="ykwD" /GFF_Attribute="listLong" misc_feature 1467686..1467705 /Source="Nicolas_upshift_promotors" /id="U1145" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.825174825174825" /psig="0.998001998001998" /xcortree=3175 /SigmaFactorBS="tattgacagctttttttactccttttcgctgtaacaactatt acaaaGGTGTTACAATTAATCTCAGtatatgtaaatatattgaatgatttgagagggg t" /listShort="S507, pbpH, kinA" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 1467699 /Source="Nicolas_upshifts" /id="U1145" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.825174825174825" /psig="0.998001998001998" /xcortree=3175 /SigmaFactorBS="tattgacagctttttttactccttttcgctgtaacaactatt acaaaGGTGTTACAATTAATCTCAGtatatgtaaatatattgaatgatttgagagggg t" /listShort="S507, pbpH, kinA" /GFF_Attribute="listLong" S_feature 1467701..1467804 /Source="Nicolas_S_feature" /locus_tag="new_1467701_1467804" /HighExp="T4.0H, T3.30H, T3.0H, Etha, T5.0H, T2.30H, LoTm, B60, T2.0H, LPhT" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.998" /TUlongSig="NA" /TUlongPSig="NA" /label="S507" CDS 1467748..1469862 /gene="pbpH" /locus_tag="BSU_13980" /old_locus_tag="BSU13980" /function="16.13: Shape" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:12896990, 23199363" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12896990, 23199363; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="penicillin-binding enzyme for formation of rod-shaped peptidoglycan cell wall" /protein_id="NP_389281.2" /db_xref="EnsemblGenomes-Gn:BSU13980" /db_xref="EnsemblGenomes-Tr:CAB13271" /db_xref="GOA:Q796K8" /db_xref="InterPro:IPR001460" /db_xref="InterPro:IPR005311" /db_xref="InterPro:IPR012338" /db_xref="InterPro:IPR036138" /db_xref="SubtiList:BG13286" /db_xref="UniProtKB/Swiss-Prot:Q796K8" /translation="MTEIGREPKKKSKGNRAIRMNLFFLAVFVLFTALIFKLGVVQIV EGEQHEEDAEKSNAKTAYYPAPRGKMYDRNQKVAVDNQSVPEIVYVSTSSTKTEDKIK TAKRLASFIHIDTEFLKERDLRDYWIAAHPKKAAALLKESESNLKGDQAYKLQIERVP DQELKAIQQDDEEMETAAIYTRFSSGNAYEPQIVKAMNPNKSNSNGKNGALLDEKKNS SQRPKNDLTYDEISIVSEHLEELPGIDIVNDWTRKYPYDKTLYSVFGGVTTPDQGLLS DRKDFYLTRGYANNDRVGKSYLEYQYEEYLNSHKEKVEYVEDNKGNVVSQKTIDKGSR GYDLQLSFDMELQAKVEKIIEEEVRNSRARGNYMLDRAFAVMMDPNNGDILSMAGKKI DLKTNKIEDYAIGAFTTQYEMGSAVKGATVLAGYQDGIPHYKYYIDAPMLLGTNLIKK SYTNMGTINELTALQKSSNVYMFNVAMHIAGVTYKPHGSLPADQNDLLKMRNYYSQFG LGVKTGIDLPQESAGMQTTPKTVGGLILDLAIGQYDTYTPLQMAQYISVIANGGYRVQ PRIVTSIHKPGKKDQLGKAIEHRKPKVLNKINNSESDLKQVQTGMKLVTSSGTAKNTF TEDVSGKTGTAETFYYGTNRNWWGKKTYNLTFVGYYPSKKPKVAFSVVVPSVDDDDKI NKIIAKRAIHAYAELEKKHSKK*" gene 1467748..1469862 /gene="pbpH" /locus_tag="BSU_13980" /old_locus_tag="BSU13980" promotor_-10 complement(1469041..1469059) /Source="Nicolas_upshift_promotors" /id="U1146" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.836163836163836" /psig="0.836163836163836" /xcortree=778 /SigmaFactorBS="ccatattagtataagatttttttataagattcgTTCCTAaaa gcattggagcatCGATATAATATTTATAATGcgggatcccgtcctgatagccggctag c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1469053) /Source="Nicolas_upshifts" /id="U1146" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.836163836163836" /psig="0.836163836163836" /xcortree=778 /SigmaFactorBS="ccatattagtataagatttttttataagattcgTTCCTAaaa gcattggagcatCGATATAATATTTATAATGcgggatcccgtcctgatagccggctag c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(1469075..1469080) /Source="Nicolas_upshift_promotors" /id="U1146" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.836163836163836" /psig="0.836163836163836" /xcortree=778 /SigmaFactorBS="ccatattagtataagatttttttataagattcgTTCCTAaaa gcattggagcatCGATATAATATTTATAATGcgggatcccgtcctgatagccggctag c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 1469843 /Source="Nicolas_upshifts" /id="D780" /incds=0 /nref=139 /ntot=246 /MaxReadThrough="3.36066" /MaxDrop="5.01597" /score="-1.2500858" /energy="-12" /TU="U1145" /idTUdmin="U1145" /TUdmin="-1862" /isTUend="FALSE" promotor_-35 1469935..1469943 /Source="Nicolas_upshift_promotors" /id="U1147" /multdbtbs="SigH" /comp="M1" /sig="SigH" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=554 /SigmaFactorBS="tcaaaaattgacgttcaccataagaataGAAGGAGAAtactc attttcTAGCGAATCATACTAGGTAaaagtcaatctgtatatgtcgaaacacgatgat c" /listShort="kinA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1469955..1469973 /Source="Nicolas_upshift_promotors" /id="U1147" /multdbtbs="SigH" /comp="M1" /sig="SigH" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=554 /SigmaFactorBS="tcaaaaattgacgttcaccataagaataGAAGGAGAAtactc attttcTAGCGAATCATACTAGGTAaaagtcaatctgtatatgtcgaaacacgatgat c" /listShort="kinA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1469967 /Source="Nicolas_upshifts" /id="U1147" /multdbtbs="SigH" /comp="M1" /sig="SigH" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=554 /SigmaFactorBS="tcaaaaattgacgttcaccataagaataGAAGGAGAAtactc attttcTAGCGAATCATACTAGGTAaaagtcaatctgtatatgtcgaaacacgatgat c" /listShort="kinA" /GFF_Attribute="listLong" CDS 1470026..1471846 /gene="kinA" /locus_tag="BSU_13990" /old_locus_tag="BSU13990" /EC_number="2.7.13.3" /function="16.3: Control" /function="16.12: Sense" /experiment="publication(s) with functional evidences, PMID:11734624, 14629015, 17350039, 21097618, 22303282, 23169620, 23378509, 23504013, 26712348, 28449380" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11734624, 14629015, 17350039, 21097618, 22303282, 23169620, 23378509, 23504013, 26712348, 28449380; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="sporulation-specific ATP-dependent protein histidine kinase" /protein_id="NP_389282.1" /db_xref="EnsemblGenomes-Gn:BSU13990" /db_xref="EnsemblGenomes-Tr:CAB13272" /db_xref="GOA:P16497" /db_xref="InterPro:IPR000014" /db_xref="InterPro:IPR001610" /db_xref="InterPro:IPR003594" /db_xref="InterPro:IPR003661" /db_xref="InterPro:IPR004358" /db_xref="InterPro:IPR005467" /db_xref="InterPro:IPR013655" /db_xref="InterPro:IPR013767" /db_xref="InterPro:IPR035965" /db_xref="InterPro:IPR036097" /db_xref="InterPro:IPR036890" /db_xref="PDB:2VLG" /db_xref="SubtiList:BG10204" /db_xref="UniProtKB/Swiss-Prot:P16497" /translation="MEQDTQHVKPLQTKTDIHAVLASNGRIIYISANSKLHLGYLQGE MIGSFLKTFLHEEDQFLVESYFYNEHHLMPCTFRFIKKDHTIVWVEAAVEIVTTRAER TEREIILKMKVLEEETGHQSLNCEKHEIEPASPESTTYITDDYERLVENLPSPLCISV KGKIVYVNSAMLSMLGAKSKDAIIGKSSYEFIEEEYHDIVKNRIIRMQKGMEVGMIEQ TWKRLDGTPVHLEVKASPTVYKNQQAELLLLIDISSRKKFQTILQKSRERYQLLIQNS IDTIAVIHNGKWVFMNESGISLFEAATYEDLIGKNIYDQLHPCDHEDVKERIQNIAEQ KTESEIVKQSWFTFQNRVIYTEMVCIPTTFFGEAAVQVILRDISERKQTEELMLKSEK LSIAGQLAAGIAHEIRNPLTAIKGFLQLMKPTMEGNEHYFDIVFSELSRIELILSELL MLAKPQQNAVKEYLNLKKLIGEVSALLETQANLNGIFIRTSYEKDSIYINGDQNQLKQ VFINLIKNAVESMPDGGTVDIIITEDEHSVHVTVKDEGEGIPEKVLNRIGEPFLTTKE KGTGLGLMVTFNIIENHQGVIHVDSHPEKGTAFKISFPKK*" gene 1470026..1471846 /gene="kinA" /locus_tag="BSU_13990" /old_locus_tag="BSU13990" CDS complement(1471857..1473038) /gene="dapX" /locus_tag="BSU_14000" /old_locus_tag="BSU14000" /EC_number="2.6.1.83" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:12670965, 14523133, 14627808, 19948795" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12670965, 14523133, 14627808, 19948795; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="N-acetyl-L,L-diaminopimelate aminotransferase" /protein_id="NP_389283.2" /db_xref="EnsemblGenomes-Gn:BSU14000" /db_xref="EnsemblGenomes-Tr:CAB13273" /db_xref="GOA:P16524" /db_xref="InterPro:IPR004838" /db_xref="InterPro:IPR004839" /db_xref="InterPro:IPR015421" /db_xref="InterPro:IPR015422" /db_xref="InterPro:IPR015424" /db_xref="SubtiList:BG10205" /db_xref="UniProtKB/Swiss-Prot:P16524" /translation="MEHLLNPKAREIEISGIRKFSNLVAQHEDVISLTIGQPDFFTPH HVKAAAKKAIDENVTSYTPNAGYLELRQAVQLYMKKKADFNYDAESEIIITTGASQAI DAAFRTILSPGDEVIMPGPIYPGYEPIINLCGAKPVIVDTTSHGFKLTARLIEDALTP NTKCVVLPYPSNPTGVTLSEEELKSIAALLKGRNVFVLSDEIYSELTYDRPHYSIATY LRDQTIVINGLSKSHSMTGWRIGFLFAPKDIAKHILKVHQYNVSCASSISQKAALEAV TNGFDDALIMREQYKKRLDYVYDRLVSMGLDVVKPSGAFYIFPSIKSFGMTSFDFSMA LLEDAGVALVPGSSFSTYGEGYVRLSFACSMDTLREGLDRLELFVLKKREAMQTINNG V*" gene complement(1471857..1473038) /gene="dapX" /locus_tag="BSU_14000" /old_locus_tag="BSU14000" downshifts complement(1471891) /Source="Nicolas_upshifts" /id="D781" /incds=0 /nref=255 /ntot=267 /MaxReadThrough="1.89632" /MaxDrop="6.70715" /score="-6.17975559" /energy="-4.7" /TU="NA" /idTUdmin="U1148" /TUdmin=0 /isTUend="TRUE" misc_feature complement(1473066..1473085) /Source="Nicolas_upshift_promotors" /id="U1148" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.928071928071928" /psig=1 /xcortree=1466 /SigmaFactorBS="gaaaaaaggcgcatacaatcgaaatatatcagttaaaaaggt gacaaatgatcagctAGTGGTAAAATAGGATAAACtcattatatttgttaaggtgatg a" /listShort="patA" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(1473082) /Source="Nicolas_upshifts" /id="U1148" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.928071928071928" /psig=1 /xcortree=1466 /SigmaFactorBS="gaaaaaaggcgcatacaatcgaaatatatcagttaaaaaggt gacaaatgatcagctAGTGGTAAAATAGGATAAACtcattatatttgttaaggtgatg a" /listShort="patA" /GFF_Attribute="listLong" promotor_-10 complement(1473114..1473132) /Source="Nicolas_upshift_promotors" /id="U1149" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=1170 /SigmaFactorBS="atcgctggttgtcttctttttttctgaaaagaaaGGTATGtt tagaaaaaaggcGCATACAATCGAAATATATcagttaaaaaggtgacaaatgatcagc t" /listShort="patA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1473126) /Source="Nicolas_upshifts" /id="U1149" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=1170 /SigmaFactorBS="atcgctggttgtcttctttttttctgaaaagaaaGGTATGtt tagaaaaaaggcGCATACAATCGAAATATATcagttaaaaaggtgacaaatgatcagc t" /listShort="patA" /GFF_Attribute="listLong" S_feature complement(1473128..1473196) /Source="Nicolas_S_feature" /locus_tag="new_1473128_1473196_c" /HighExp="M9-stat, Lbtran, Lbstat, T3.30H, T3.0H, T2.30H, M0t90, T4.0H, M40t90, T1.30H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="1, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S508" promotor_-35 complement(1473147..1473152) /Source="Nicolas_upshift_promotors" /id="U1149" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=1170 /SigmaFactorBS="atcgctggttgtcttctttttttctgaaaagaaaGGTATGtt tagaaaaaaggcGCATACAATCGAAATATATcagttaaaaaggtgacaaatgatcagc t" /listShort="patA" /GFF_Attribute="listLong" /label="promotor_-35" misc_feature complement(1473190..1473209) /Source="Nicolas_upshift_promotors" /id="U1150" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.99000999000999" /psig=1 /xcortree=3165 /SigmaFactorBS="ttgattatggctattaatgaaattggcacatataaacaataa tagaaCATGATACAATAAAGACAATcaaatcgctggttgtcttctttttttctgaaaa g" /listShort="S508, patA" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(1473196) /Source="Nicolas_upshifts" /id="U1150" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.99000999000999" /psig=1 /xcortree=3165 /SigmaFactorBS="ttgattatggctattaatgaaattggcacatataaacaataa tagaaCATGATACAATAAAGACAATcaaatcgctggttgtcttctttttttctgaaaa g" /listShort="S508, patA" /GFF_Attribute="listLong" CDS complement(1473240..1473401) /gene="ykzT" /locus_tag="BSU_14009" /old_locus_tag="BSU14009" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_003097722.1" /db_xref="EnsemblGenomes-Gn:BSU14009" /db_xref="EnsemblGenomes-Tr:CAX52613" /db_xref="UniProtKB/Swiss-Prot:C0H406" /translation="MGTLVIFKENEMTVLEDISEETYLNMKKESADLQEEHPPYLIWH EDLHFDYGY*" gene complement(1473240..1473401) /gene="ykzT" /locus_tag="BSU_14009" /old_locus_tag="BSU14009" promotor_-10 complement(1473424..1473443) /Source="Nicolas_upshift_promotors" /id="U1151" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.702297702297702" /psig=1 /xcortree=2406 /SigmaFactorBS="gttcctcaaaaaagaaacttttttcctaataacCATTGACTt tccaactaacagTGATAAAATAGTCAAGGATTtttccaaagaagggtgtaaataatgg g" /listShort="ykzT, S508, patA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1473437) /Source="Nicolas_upshifts" /id="U1151" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.702297702297702" /psig=1 /xcortree=2406 /SigmaFactorBS="gttcctcaaaaaagaaacttttttcctaataacCATTGACTt tccaactaacagTGATAAAATAGTCAAGGATTtttccaaagaagggtgtaaataatgg g" /listShort="ykzT, S508, patA" /GFF_Attribute="listLong" promotor_-35 complement(1473457..1473464) /Source="Nicolas_upshift_promotors" /id="U1151" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.702297702297702" /psig=1 /xcortree=2406 /SigmaFactorBS="gttcctcaaaaaagaaacttttttcctaataacCATTGACTt tccaactaacagTGATAAAATAGTCAAGGATTtttccaaagaagggtgtaaataatgg g" /listShort="ykzT, S508, patA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1473538..1473545 /Source="Nicolas_upshift_promotors" /id="U1152" /multdbtbs="SigD" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2811 /SigmaFactorBS="cgcggcttgttgccttcggaattcgattttgaagagctgccA TTCACTTtttacaaattacGCCGATATATACAGTACAAtactgaatgcgaatagcgag g" /listShort="cheV" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 1473557 /Source="Nicolas_upshifts" /id="U1152" /multdbtbs="SigD" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2811 /SigmaFactorBS="cgcggcttgttgccttcggaattcgattttgaagagctgccA TTCACTTtttacaaattacGCCGATATATACAGTACAAtactgaatgcgaatagcgag g" /listShort="cheV" /GFF_Attribute="listLong" promotor_-10 1473558..1473576 /Source="Nicolas_upshift_promotors" /id="U1152" /multdbtbs="SigD" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2811 /SigmaFactorBS="cgcggcttgttgccttcggaattcgattttgaagagctgccA TTCACTTtttacaaattacGCCGATATATACAGTACAAtactgaatgcgaatagcgag g" /listShort="cheV" /GFF_Attribute="listLong" /label="promotor_-10" CDS 1473605..1474516 /gene="cheV" /locus_tag="BSU_14010" /old_locus_tag="BSU14010" /function="16.12: Sense" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:11553614, 12864845, 14731274, 14993307, 26844549" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11553614, 12864845, 14731274, 14993307, 26844549; Product type r: regulator" /codon_start=1 /transl_table=11 /product="coupling protein and response regulator for CheAactivity in response to attractants (chemotaxis)" /protein_id="NP_389284.1" /db_xref="EnsemblGenomes-Gn:BSU14010" /db_xref="EnsemblGenomes-Tr:CAB13274" /db_xref="GOA:P37599" /db_xref="InterPro:IPR001789" /db_xref="InterPro:IPR002545" /db_xref="InterPro:IPR011006" /db_xref="InterPro:IPR024181" /db_xref="InterPro:IPR036061" /db_xref="SubtiList:BG10823" /db_xref="UniProtKB/Swiss-Prot:P37599" /translation="MSLQQYEILLDSGTNELEIVKFGVGENAFGINVMKVREIIQPVE VTSVPHSHQHVEGMIKLRGEILPVISLFSFFGVEPEGSKDEKYIVTEFNKRKIVFHVG SVSQIHRVSWEAIEKPTSLNQGMERHLTGIIKLEDLMIFLPDYEKIIYDIESDSGVDT YNMHTEGFDERRTDKKLIIVEDSPLLMRLLQDELKEAGYNNIASFENGKEAYEYIMNL AENETDLSKQIDMIITDIEMPKMDGHRLTKLLKENPKSSDVPVMIFSSLITDDLRHRG EVVGADEQISKPEISDLIKKVDTYVIE*" gene 1473605..1474516 /gene="cheV" /locus_tag="BSU_14010" /old_locus_tag="BSU14010" downshifts complement(1473610) /Source="Nicolas_upshifts" /id="D782" /incds=0 /nref=1 /ntot=50 /MaxReadThrough="1.14523" /MaxDrop="3.62759" /score="-8.29055697" /energy="-7.7" /TU="NA" /idTUdmin="U1154" /TUdmin=968 /isTUend="FALSE" promotor_-35 1474059..1474067 /Source="Nicolas_upshift_promotors" /id="U1153" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.54045954045954" /psig="0.54045954045954" /xcortree=750 /SigmaFactorBS="ctttttgcctgactatgaaaaaattatttatgacaTTGAATC AGattcaggtgttgaCACGTATAATATGCATACcgagggcttcgatgaaagaagaact g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1474081..1474098 /Source="Nicolas_upshift_promotors" /id="U1153" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.54045954045954" /psig="0.54045954045954" /xcortree=750 /SigmaFactorBS="ctttttgcctgactatgaaaaaattatttatgacaTTGAATC AGattcaggtgttgaCACGTATAATATGCATACcgagggcttcgatgaaagaagaact g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1474084 /Source="Nicolas_upshifts" /id="U1153" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.54045954045954" /psig="0.54045954045954" /xcortree=750 /SigmaFactorBS="ctttttgcctgactatgaaaaaattatttatgacaTTGAATC AGattcaggtgttgaCACGTATAATATGCATACcgagggcttcgatgaaagaagaact g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" downshifts 1474501 /Source="Nicolas_upshifts" /id="D783" /incds=0 /nref=188 /ntot=251 /MaxReadThrough="4.61331" /MaxDrop="6.23797" /score="15.4598573" /energy="-13.1" /TU="U1152" /idTUdmin="U1153" /TUdmin="-1" /isTUend="TRUE" CDS complement(1474560..1475024) /gene="kre" /locus_tag="BSU_14020" /old_locus_tag="BSU14020" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1a: Function from experimental evidences in the studied strain; Product type r: regulator" /codon_start=1 /transl_table=11 /product="regulator of transcription factor ComK function via modulation of mRNA stability" /protein_id="NP_389285.1" /db_xref="EnsemblGenomes-Gn:BSU14020" /db_xref="EnsemblGenomes-Tr:CAB13275" /db_xref="InterPro:IPR025552" /db_xref="SubtiList:BG11202" /db_xref="UniProtKB/Swiss-Prot:P42430" /translation="MDDHAYTKDLQPTVENLSKAVYTVNRHAKTAPNPKYLYLLKKRA LQKLVKEGKGKKIGLHFSKNPRFSQQQSDVLISIGDYYFHMPPTKEDFEHLPHLGTLN QSYRNPKAQMSLTKAKHLLQEYVGMKEKPLVPNRQQPAYHKPVFKKLGESYF*" gene complement(1474560..1475024) /gene="kre" /locus_tag="BSU_14020" /old_locus_tag="BSU14020" downshifts complement(1474578) /Source="Nicolas_upshifts" /id="D784" /incds=0 /nref=212 /ntot=260 /MaxReadThrough="2.67186" /MaxDrop="6.66359" /score="16.1985615" /energy="-13.1" /TU="NA" /idTUdmin="U1154" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(1475054..1475073) /Source="Nicolas_upshift_promotors" /id="U1154" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.878121878121878" /psig="0.99100899100899" /xcortree=2996 /SigmaFactorBS="cttagaaaaaagcgcatttttacattcaaTATTTGCAtttca actttaaaaAAGTATAATCTAAACATATAgaaattgataagagcaaaggagagaaata a" /listShort="ykyB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1475064) /Source="Nicolas_upshifts" /id="U1154" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.878121878121878" /psig="0.99100899100899" /xcortree=2996 /SigmaFactorBS="cttagaaaaaagcgcatttttacattcaaTATTTGCAtttca actttaaaaAAGTATAATCTAAACATATAgaaattgataagagcaaaggagagaaata a" /listShort="ykyB" /GFF_Attribute="listLong" promotor_-35 complement(1475088..1475095) /Source="Nicolas_upshift_promotors" /id="U1154" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.878121878121878" /psig="0.99100899100899" /xcortree=2996 /SigmaFactorBS="cttagaaaaaagcgcatttttacattcaaTATTTGCAtttca actttaaaaAAGTATAATCTAAACATATAgaaattgataagagcaaaggagagaaata a" /listShort="ykyB" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(1475150..1476442) /gene="ykuC" /locus_tag="BSU_14030" /old_locus_tag="BSU14030" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative transporter" /protein_id="NP_389286.2" /db_xref="EnsemblGenomes-Gn:BSU14030" /db_xref="EnsemblGenomes-Tr:CAB13276" /db_xref="GOA:O31695" /db_xref="InterPro:IPR004751" /db_xref="InterPro:IPR011701" /db_xref="InterPro:IPR020846" /db_xref="InterPro:IPR036259" /db_xref="SubtiList:BG13287" /db_xref="UniProtKB/Swiss-Prot:O31695" /translation="MDIFKNRNFVRLFFAALASQMGTTVGNMAFAFFLLDRFSSQPSY TTLAELMYSLPTIFVFLIVGVVADRFDRKKVAENCDWIRAGLTVVLFFTLFTGNIPLV FCILFIRSAVTKFFFPAENSLVQAILPKEHYAKAAGLNQMLFSIFMVFGVGIGAFMYN TIGIEGAIILDFVSFIISGLLIRSCRIPKEARQPNGAFSWRKTSVKDSINDFREGILY ILKNKLLASLIFGFFIFGFVNGGFAVLPMFTMKYGLAPDRYEWHTSVFTIALGFGLLA GSVIGTLISKKVKPHFLMSIPIFIAGLLIFVLGYTNILWVYYAAAFALGMCIGPINIA IGGWMPKIVHPKLMGRVSGMQDPFMMFAQSLTLGLVALLFPKFVSNIDYLYYGMGVII LLVFIFYFIALPKYSAQAVEVNVQEAFQEQPKKKARSV*" gene complement(1475150..1476442) /gene="ykuC" /locus_tag="BSU_14030" /old_locus_tag="BSU14030" downshifts complement(1475172) /Source="Nicolas_upshifts" /id="D785" /incds=0 /nref=37 /ntot=206 /MaxReadThrough="4.24449" /MaxDrop="4.31411" /score="3.5676583" /energy="-14.2" /TU="U1155" /idTUdmin="U1156" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(1476466..1476485) /Source="Nicolas_upshift_promotors" /id="U1155" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.831168831168831" /psig="0.997002997002997" /xcortree=1817 /SigmaFactorBS="gattaaccggtaatgttttcttattTGTTTcaaaaacaggcg gttTATAATATGATAAAGTGGGAcctttagggtaaggagcgtttttatggatatattt a" /listShort="ykuC" /listLong="ykyB" /label="promotor_-10" upshifts complement(1476470) /Source="Nicolas_upshifts" /id="U1155" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.831168831168831" /psig="0.997002997002997" /xcortree=1817 /SigmaFactorBS="gattaaccggtaatgttttcttattTGTTTcaaaaacaggcg gttTATAATATGATAAAGTGGGAcctttagggtaaggagcgtttttatggatatattt a" /listShort="ykuC" /listLong="ykyB" promotor_-35 complement(1476501..1476505) /Source="Nicolas_upshift_promotors" /id="U1155" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.831168831168831" /psig="0.997002997002997" /xcortree=1817 /SigmaFactorBS="gattaaccggtaatgttttcttattTGTTTcaaaaacaggcg gttTATAATATGATAAAGTGGGAcctttagggtaaggagcgtttttatggatatattt a" /listShort="ykuC" /listLong="ykyB" /label="promotor_-35" CDS complement(1476518..1477012) /gene="ltdD" /locus_tag="BSU_14040" /old_locus_tag="BSU14040" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:11011148, 16287140, 23832002" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11011148, 16287140, 23832002; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="murein L,D-transpeptidase" /protein_id="NP_389287.1" /db_xref="EnsemblGenomes-Gn:BSU14040" /db_xref="EnsemblGenomes-Tr:CAB13277" /db_xref="GOA:O34816" /db_xref="InterPro:IPR005490" /db_xref="InterPro:IPR018392" /db_xref="InterPro:IPR036779" /db_xref="PDB:1Y7M" /db_xref="PDB:2MTZ" /db_xref="PDB:3ZQD" /db_xref="PDB:4A1I" /db_xref="PDB:4A1J" /db_xref="PDB:4A1K" /db_xref="PDB:4A52" /db_xref="SubtiList:BG13288" /db_xref="UniProtKB/Swiss-Prot:O34816" /translation="MLTYQVKQGDTLNSIAADFRISTAALLQANPSLQAGLTAGQSIV IPGLPDPYTIPYHIAVSIGAKTLTLSLNNRVMKTYPIAVGKILTQTPTGEFYIINRQR NPGGPFGAYWLSLSKQHYGIHGTNNPASIGKAVSKGCIRMHNKDVIELASIVPNGTRV TINR*" gene complement(1476518..1477012) /gene="ltdD" /locus_tag="BSU_14040" /old_locus_tag="BSU14040" promotor_-10 complement(1477028..1477047) /Source="Nicolas_upshift_promotors" /id="U1156" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp="0.994005994005994" /psig="0.994005994005994" /xcortree=1309 /SigmaFactorBS="gaaatcactgtcttcaccttaaaaagcacaaattAATGTAGC AGgatgggctcctcaTCAATACTTATAAGTAAAAAaggaggatgaggaaactgcttac g" /listShort="ykuD, ykuC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1477044) /Source="Nicolas_upshifts" /id="U1156" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp="0.994005994005994" /psig="0.994005994005994" /xcortree=1309 /SigmaFactorBS="gaaatcactgtcttcaccttaaaaagcacaaattAATGTAGC AGgatgggctcctcaTCAATACTTATAAGTAAAAAaggaggatgaggaaactgcttac g" /listShort="ykuD, ykuC" /GFF_Attribute="listLong" promotor_-35 complement(1477061..1477070) /Source="Nicolas_upshift_promotors" /id="U1156" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp="0.994005994005994" /psig="0.994005994005994" /xcortree=1309 /SigmaFactorBS="gaaatcactgtcttcaccttaaaaagcacaaattAATGTAGC AGgatgggctcctcaTCAATACTTATAAGTAAAAAaggaggatgaggaaactgcttac g" /listShort="ykuD, ykuC" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(1477069..1477929) /gene="ppeE" /locus_tag="BSU_14050" /old_locus_tag="BSU14050" /EC_number="3.1.-.-" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:22767609, 24140208" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 22767609, 24140208; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="exported metallophosphoesterase (Mn2+ and Zn2+)" /protein_id="NP_389288.2" /db_xref="EnsemblGenomes-Gn:BSU14050" /db_xref="EnsemblGenomes-Tr:CAB13278" /db_xref="GOA:O34870" /db_xref="InterPro:IPR004843" /db_xref="InterPro:IPR006311" /db_xref="InterPro:IPR019546" /db_xref="InterPro:IPR029052" /db_xref="SubtiList:BG13289" /db_xref="UniProtKB/Swiss-Prot:O34870" /translation="MKKMSRRQFLKGMFGALAAGALTAGGGYGYARYLEPHMIETTEH TIKSSLIPHGFDGFKIVQFSDAHLSDYFTLEDLKTVILTINESKPDLIVFTGDIIDNP DTYQHHQAVIPLLRKLNAPFGKLCIYGNHDHGGYGTAVYKSLMTAGGFTVYRNGYQTL SLADGSKIEIASLDDLMLGNPDYEGTLSRLSDRLFSILLVHEPDAALKTTDYPVNLQL SGHTHGGQIQLPFYGPIITPPYGKVYTEGMYQTGSTHIYVNRGLGMTRLPLRFLAKPE ITVFTLKSTN*" gene complement(1477069..1477929) /gene="ppeE" /locus_tag="BSU_14050" /old_locus_tag="BSU14050" misc_feature complement(1477950..1477969) /Source="Nicolas_upshift_promotors" /id="U1157" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.885114885114885" /psig="0.997002997002997" /xcortree=1947 /SigmaFactorBS="attatatccctgcctctgtcagcacatgctcatatgagattt ttatcagatacaGATGATATAATAGAAAAACTctattaaaggttggtttgaaatgaaa a" /listShort="ykuE, ykuD" /listLong="ykuC, ykyB" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(1477963) /Source="Nicolas_upshifts" /id="U1157" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.885114885114885" /psig="0.997002997002997" /xcortree=1947 /SigmaFactorBS="attatatccctgcctctgtcagcacatgctcatatgagattt ttatcagatacaGATGATATAATAGAAAAACTctattaaaggttggtttgaaatgaaa a" /listShort="ykuE, ykuD" /listLong="ykuC, ykyB" promotor_-35 1478000..1478007 /Source="Nicolas_upshift_promotors" /id="U1158" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.781218781218781" /psig="0.97002997002997" /xcortree=404 /SigmaFactorBS="tgataaaaatctcatatgagcatgTGCTGACAgaggcaggga tataaTGATAGAATATTATTGAATGaataatcattcacaattggagggataaacatgg a" /listShort="fadH, S509, S510, fadG, ykzU, ykuH" /listLong="S511, ykuI" /label="promotor_-35" promotor_-10 1478023..1478042 /Source="Nicolas_upshift_promotors" /id="U1158" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.781218781218781" /psig="0.97002997002997" /xcortree=404 /SigmaFactorBS="tgataaaaatctcatatgagcatgTGCTGACAgaggcaggga tataaTGATAGAATATTATTGAATGaataatcattcacaattggagggataaacatgg a" /listShort="fadH, S509, S510, fadG, ykzU, ykuH" /listLong="S511, ykuI" /label="promotor_-10" upshifts 1478036 /Source="Nicolas_upshifts" /id="U1158" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.781218781218781" /psig="0.97002997002997" /xcortree=404 /SigmaFactorBS="tgataaaaatctcatatgagcatgTGCTGACAgaggcaggga tataaTGATAGAATATTATTGAATGaataatcattcacaattggagggataaacatgg a" /listShort="fadH, S509, S510, fadG, ykzU, ykuH" /listLong="S511, ykuI" CDS 1478072..1478836 /gene="fadH" /locus_tag="BSU_14060" /old_locus_tag="BSU14060" /EC_number="1.3.1.34" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 17189250, 21398533; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative 2,4-dienoyl-CoA reductase" /protein_id="NP_389289.1" /db_xref="EnsemblGenomes-Gn:BSU14060" /db_xref="EnsemblGenomes-Tr:CAB13279" /db_xref="GOA:O34717" /db_xref="InterPro:IPR002347" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG13290" /db_xref="UniProtKB/Swiss-Prot:O34717" /translation="MEKKAVIITGGSSGMGKAMAKKQAELGWHVMVTGRNHEALEETK KEIQTFEGQVACFQMDVRSDSAASDMIKEAVKAFGRLDALINNAAGNFICPAEKLTPN GWKAVIEIVLNGTFFCSQAAARHWIDQKQQGVILNMAATYAWGAGAGVVHSAAAKAGV LSLTRTLAVEWGSKYGIRTNAIAPGPIERTGGAEKLFESEKAMARTMNSVPLGRLGTP EEIAALAAFLLSDEASYINGDCITMDGGQWLNPYPF*" gene 1478072..1478836 /gene="fadH" /locus_tag="BSU_14060" /old_locus_tag="BSU14060" S_feature 1478837..1478985 /Source="Nicolas_S_feature" /locus_tag="new_1478837_1478985" /HighExp="T0.30H, T1.0H, B60, Sw, BC, LoTm, M9-stat, S8, S7, BT" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.97" /TUlongSig="NA" /TUlongPSig="NA" /label="S509" misc_feature 1478966..1478984 /Source="Nicolas_upshift_promotors" /id="U1159" /multdbtbs="-" /comp="M12" /sig="Sig-" /pcomp="0.999000999001" /psig=0 /xcortree=1521 /SigmaFactorBS="tgataacacatagagctttatttgtttatgaggtgttgtGTC ATACGTAAGCCACCTAatatatgaaaggtatattttaaaaggggagacgaaatatgaa g" /listShort="S510, fadG, ykzU, ykuH, S511, ykuI, S512" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" S_feature 1478987..1479136 /Source="Nicolas_S_feature" /locus_tag="new_1478987_1479136" /HighExp="T0.30H, M40t90, T1.0H, B60, BC, Sw, LPh, LoTm, M9-stat, HPh" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="Sig-, SigA" /TUshortPSig="0, 0.97" /TUlongSig="NA" /TUlongPSig="NA" /label="S510" upshifts 1478987 /Source="Nicolas_upshifts" /id="U1159" /multdbtbs="-" /comp="M12" /sig="Sig-" /pcomp="0.999000999001" /psig=0 /xcortree=1521 /SigmaFactorBS="tgataacacatagagctttatttgtttatgaggtgttgtGTC ATACGTAAGCCACCTAatatatgaaaggtatattttaaaaggggagacgaaatatgaa g" /listShort="S510, fadG, ykzU, ykuH, S511, ykuI, S512" /GFF_Attribute="listLong" downshifts complement(1479034) /Source="Nicolas_upshifts" /id="D786" /incds=0 /nref=3 /ntot=49 /MaxReadThrough="1.82681" /MaxDrop="3.39884" /score="-0.170855674" /energy="-4.8" /TU="NA" /idTUdmin="U1157" /TUdmin="-2542" /isTUend="FALSE" CDS 1479137..1480867 /gene="ykuG" /locus_tag="BSU_14071" /old_locus_tag="BSU14071" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 17189250; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative cell wall-binding protein" /protein_id="YP_003097723.1" /db_xref="EnsemblGenomes-Gn:BSU14071" /db_xref="EnsemblGenomes-Tr:CAX52614" /db_xref="InterPro:IPR002477" /db_xref="InterPro:IPR015020" /db_xref="InterPro:IPR017853" /db_xref="InterPro:IPR036365" /db_xref="InterPro:IPR036366" /db_xref="UniProtKB/Swiss-Prot:O34320" /translation="MDEMVLLTQEWLNETYKGKSGYNSIEENGKTGWKTMYALTRALQ LELGITQTSDSFGPTTLRKLKELGPISTSTNSKKNIVKIIQGALYCKGYGPGGLTGTF GQGTKEAIAEMQLHMGLSKTDGVVTPKVFKALLNMDSYILLNGASEKVRSIQQWLNNK YYNRENFYFMPCDGLYSRDTQKSLVYAIQYEEGLSDSIANGNFGPTTQRLIPVLRIGE TDEKNSFIHLFQAALIFNGYNVPFDGVYSESVRSKVKAFQSFAKLQQSGTADFQTWAS LLVSTGDPNRKGVACDSITQITSDRAESLKRAGYKIVGRYLTNAPGSTLNKKIQPGEL ETILKSGLNVFPIYQTYGGATNYFNKEQGKKDAFAAYKAAKEYGFKNNTVIYFAVDYD AYGNDLNNNIIPHFEGINEIMNGFLGSTYKIGIYAPRNVCTIVSKKGLAFASFVSGMS TGFSGNLGYPLPYNWAFDQISTITVGNGSGMIEIDNDICSGLDNGVNTINIVPSENKK FFDQIDVLYETAEKYAQMQSDLNNGVKKTQLANELVAQYLRKDDYKGWKWVPTAGQID PIYREWAVKR*" gene 1479137..1480867 /gene="ykuG" /locus_tag="BSU_14071" /old_locus_tag="BSU14071" CDS 1480933..1481451 /gene="ykzU" /locus_tag="BSU_14072" /old_locus_tag="BSU14072" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="YP_003097724.1" /db_xref="EnsemblGenomes-Gn:BSU14072" /db_xref="EnsemblGenomes-Tr:CAX52615" /db_xref="UniProtKB/Swiss-Prot:C0H408" /translation="MATYNAIIYSGGYSQTLRDFAGWTGDLLTTIQDMKLHAQEFNSP YDAAMKIIGNMYQFSLDDLFSDVDAINLANKTSVGANAQPLNIAIRDYYSNNDCMNRF TQFVNNRFDGSLDKIFSEAEYYLNTNLDPVVVPIRLAFKRAFDVEDYSEEIGKITAQA FRDVIEKKMISE*" gene 1480933..1481451 /gene="ykzU" /locus_tag="BSU_14072" /old_locus_tag="BSU14072" downshifts 1481449 /Source="Nicolas_upshifts" /id="D787" /incds=0 /nref=1 /ntot=11 /MaxReadThrough="5.57306" /MaxDrop="3.8585" /score="8.20824413" /energy="-13" /TU="U1158,U1159" /idTUdmin="U1158" /TUdmin="-682" /isTUend="FALSE" promotor_-35 1481494..1481499 /Source="Nicolas_upshift_promotors" /id="U1160" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.98901098901099" /psig=1 /xcortree=2279 /SigmaFactorBS="gcaaaacaagcgaacgttaaaactggtcgttcgcttgttTTA TTTtctatttaaattTATGATATAATTTTTAAAGAttaaggagtgattcattgaagaa a" /listShort="ykuH, S511, ykuI" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1481512..1481531 /Source="Nicolas_upshift_promotors" /id="U1160" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.98901098901099" /psig=1 /xcortree=2279 /SigmaFactorBS="gcaaaacaagcgaacgttaaaactggtcgttcgcttgttTTA TTTtctatttaaattTATGATATAATTTTTAAAGAttaaggagtgattcattgaagaa a" /listShort="ykuH, S511, ykuI" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1481515 /Source="Nicolas_upshifts" /id="U1160" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.98901098901099" /psig=1 /xcortree=2279 /SigmaFactorBS="gcaaaacaagcgaacgttaaaactggtcgttcgcttgttTTA TTTtctatttaaattTATGATATAATTTTTAAAGAttaaggagtgattcattgaagaa a" /listShort="ykuH, S511, ykuI" /GFF_Attribute="listLong" CDS 1481547..1482095 /gene="ykuH" /locus_tag="BSU_14080" /old_locus_tag="BSU14080" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_389291.1" /db_xref="EnsemblGenomes-Gn:BSU14080" /db_xref="EnsemblGenomes-Tr:CAB13281" /db_xref="GOA:O31696" /db_xref="SubtiList:BG13292" /db_xref="UniProtKB/Swiss-Prot:O31696" /translation="MKKLLKKLVVLFLSSLVIIFNVWYFIICAFSPEYYQNTNLTSNE IIRFEKLYHIDFPDETKFIKAREYLAGPGGDTSAVLYVSLPTKRVEKVLSDYTYMKIN YTDNVGSMYGVDVSKSVAGLTTLTFGTYDKKGTFYNMKHDDDWMYKGTDWNLYFWTAA SYNAVIFVFVLVIVKQMNKILN*" gene 1481547..1482095 /gene="ykuH" /locus_tag="BSU_14080" /old_locus_tag="BSU14080" S_feature 1482096..1482247 /Source="Nicolas_S_feature" /locus_tag="new_1482096_1482247" /HighExp="HiOs, LPhT, Salt, T0.0H, HiTm, T-0.40H, Fru, T-1.10H, LPh, T-4.40H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, Sig-" /TUshortPSig="1, 0" /TUlongSig="SigA" /TUlongPSig="0.97" /label="S511" CDS 1482248..1483471 /gene="ykuI" /locus_tag="BSU_14090" /old_locus_tag="BSU14090" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 19244251, 28536559; Product type rc: receptor" /codon_start=1 /transl_table=11 /product="putative cyclic-di-GMP receptor (no phosphodiesterase activity)" /protein_id="NP_389292.1" /db_xref="EnsemblGenomes-Gn:BSU14090" /db_xref="EnsemblGenomes-Tr:CAB13282" /db_xref="InterPro:IPR001633" /db_xref="InterPro:IPR018842" /db_xref="InterPro:IPR029151" /db_xref="InterPro:IPR035919" /db_xref="PDB:2BAS" /db_xref="PDB:2W27" /db_xref="SubtiList:BG13293" /db_xref="UniProtKB/Swiss-Prot:O35014" /translation="MLDPLDILTNIDDVLPYYQAIFSAEEQKVVGYEVLGRILADSEI QSLGPFFLDAGIPEEYKLEVDNRIIRQALDRFLEADSDLLIFMNQDANLLMLDHGESF LELLKEYEAKGIELHRFVLEITEHNFEGDIEQLYHMLAYYRTYGIKIAVDNIGKESSN LDRIALLSPDLLKIDLQALKVSQPSPSYEHVLYSISLLARKIGAALLYEDIEANFQLQ YAWRNGGRYFQGYYLVSPSETFLERDVLKQRLKTEFHQFITHEKKKLETVYEHSEQFY KRVHQAVTSLRKNNLSSDDDFIKKLAEELTDCSFRIYMCDEEGDQLTGNVFKQDGEWI YQPEYAEKNWSWRPYFLENIMRMRNLRKGFFSDLYSDLETGEMIRTFSYPMDDQMYLF IDLPYSYLYEQDGLI*" gene 1482248..1483471 /gene="ykuI" /locus_tag="BSU_14090" /old_locus_tag="BSU14090" promotor_-10 complement(1483434..1483452) /Source="Nicolas_upshift_promotors" /id="U1161" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=1186 /SigmaFactorBS="tttcatttcataaaaaaaacggcctttcagccGTTAAAtcag tccgtcctgcTCATATAAATAAGAATAAGgcaagtctataaataaatacatctgatca t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1483444) /Source="Nicolas_upshifts" /id="U1161" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=1186 /SigmaFactorBS="tttcatttcataaaaaaaacggcctttcagccGTTAAAtcag tccgtcctgcTCATATAAATAAGAATAAGgcaagtctataaataaatacatctgatca t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" downshifts 1483450 /Source="Nicolas_upshifts" /id="D788" /incds=0 /nref=132 /ntot=229 /MaxReadThrough="3.48305" /MaxDrop="4.61382" /score="32.6727777" /energy="-7.5" /TU="U1159" /idTUdmin="U1160" /TUdmin="-1" /isTUend="TRUE" promotor_-35 complement(1483467..1483472) /Source="Nicolas_upshift_promotors" /id="U1161" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=1186 /SigmaFactorBS="tttcatttcataaaaaaaacggcctttcagccGTTAAAtcag tccgtcctgcTCATATAAATAAGAATAAGgcaagtctataaataaatacatctgatca t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1483520..1483527 /Source="Nicolas_upshift_promotors" /id="U1162" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.971028971028971" /psig=1 /xcortree=2096 /SigmaFactorBS="aaggccgttttttttatgaaatgaaaaaaatatcaaaaaacG ATTGACAttgatactgagaatCATTATCATTTAATTATAGAgagaagctactctctgt t" /listShort="S512, S513, S514, ykuJ, S515, ykuK, ykzF" /listLong="S516, ykuL, S517, ccpC" /label="promotor_-35" S_feature 1483539..1483640 /Source="Nicolas_S_feature" /locus_tag="new_1483539_1483640" /HighExp="B36, B60, nit, Pyr, BI, HiOs, T-0.40H, S5, GM 15, S4" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, Sig-" /TUshortPSig="1, 0" /TUlongSig="NA" /TUlongPSig="NA" /label="S512" upshifts 1483539 /Source="Nicolas_upshifts" /id="U1162" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.971028971028971" /psig=1 /xcortree=2096 /SigmaFactorBS="aaggccgttttttttatgaaatgaaaaaaatatcaaaaaacG ATTGACAttgatactgagaatCATTATCATTTAATTATAGAgagaagctactctctgt t" /listShort="S512, S513, S514, ykuJ, S515, ykuK, ykzF" /listLong="S516, ykuL, S517, ccpC" promotor_-10 1483542..1483561 /Source="Nicolas_upshift_promotors" /id="U1162" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.971028971028971" /psig=1 /xcortree=2096 /SigmaFactorBS="aaggccgttttttttatgaaatgaaaaaaatatcaaaaaacG ATTGACAttgatactgagaatCATTATCATTTAATTATAGAgagaagctactctctgt t" /listShort="S512, S513, S514, ykuJ, S515, ykuK, ykzF" /listLong="S516, ykuL, S517, ccpC" /label="promotor_-10" misc_RNA 1483557..1483640 /gene="fsrA" /locus_tag="BSU_misc_RNA_69" /product="regulatory RNA controlling iron-dependent metabolism" /experiment="publication(s) with functional evidences, PMID:18697947, 22389480, 22427629, 24576839" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 18697947, 22389480, 22427629, 24576839; Product type n: RNA" /function="12: Regulatory functions" gene 1483557..1483640 /gene="fsrA" /locus_tag="BSU_misc_RNA_69" downshifts 1483597 /Source="Nicolas_upshifts" /id="D789" /incds=0 /nref=61 /ntot=192 /MaxReadThrough="6.41968" /MaxDrop="7.54463" /score="16.5898261" /energy="-8.8" /TU="U1159,U1162" /idTUdmin="U1159" /TUdmin="-74" /isTUend="FALSE" promotor_-35 1483651..1483656 /Source="Nicolas_upshift_promotors" /id="U1163" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=1032 /SigmaFactorBS="aaaacttggcgctacccccgccaagttttttatttgtcaaAG CATAggacaatccaatgaaaCAATAAACCTAACTAGTGGtaaacgtttaacacgggga g" /listShort="S513, S514, ykuJ, S515, ykuK" /listLong="ykzF, S516, ykuL, S517, ccpC" /label="promotor_-35" S_feature 1483671..1483955 /Source="Nicolas_S_feature" /locus_tag="new_1483671_1483955" /HighExp="S4, H2O2, S5, Paraq, B60, nit, GM 10, B36, GM 25, GM 15" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.147452" /TUshortSig="SigEF, SigA" /TUshortPSig="0.997, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S513" upshifts 1483671 /Source="Nicolas_upshifts" /id="U1163" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=1032 /SigmaFactorBS="aaaacttggcgctacccccgccaagttttttatttgtcaaAG CATAggacaatccaatgaaaCAATAAACCTAACTAGTGGtaaacgtttaacacgggga g" /listShort="S513, S514, ykuJ, S515, ykuK" /listLong="ykzF, S516, ykuL, S517, ccpC" promotor_-10 1483673..1483691 /Source="Nicolas_upshift_promotors" /id="U1163" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=1032 /SigmaFactorBS="aaaacttggcgctacccccgccaagttttttatttgtcaaAG CATAggacaatccaatgaaaCAATAAACCTAACTAGTGGtaaacgtttaacacgggga g" /listShort="S513, S514, ykuJ, S515, ykuK" /listLong="ykzF, S516, ykuL, S517, ccpC" /label="promotor_-10" promotor_-35 1483932..1483938 /Source="Nicolas_upshift_promotors" /id="U1164" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=786 /SigmaFactorBS="atgctgccaaagattcgaaaaaaattataattatgTGCATGA cattcaaaaaaagCCTCAAACTAAAgaaaaatagtttttttcactttttttctttgct t" /listShort="S514, ykuJ, S515, ykuK, ykzF" /listLong="S516, ykuL, S517, ccpC" /label="promotor_-35" promotor_-10 1483952..1483963 /Source="Nicolas_upshift_promotors" /id="U1164" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=786 /SigmaFactorBS="atgctgccaaagattcgaaaaaaattataattatgTGCATGA cattcaaaaaaagCCTCAAACTAAAgaaaaatagtttttttcactttttttctttgct t" /listShort="S514, ykuJ, S515, ykuK, ykzF" /listLong="S516, ykuL, S517, ccpC" /label="promotor_-10" S_feature 1483957..1484044 /Source="Nicolas_S_feature" /locus_tag="new_1483957_1484044" /HighExp="S5, S4, H2O2, B60, Paraq, nit, B36, GM 10, S7, S6" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigGF, SigEF, SigA" /TUshortPSig="0.999, 0.997, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S514" upshifts 1483957 /Source="Nicolas_upshifts" /id="U1164" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=786 /SigmaFactorBS="atgctgccaaagattcgaaaaaaattataattatgTGCATGA cattcaaaaaaagCCTCAAACTAAAgaaaaatagtttttttcactttttttctttgct t" /listShort="S514, ykuJ, S515, ykuK, ykzF" /listLong="S516, ykuL, S517, ccpC" misc_feature 1484033..1484052 /Source="Nicolas_upshift_promotors" /id="U1165" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.48951048951049" /psig=1 /xcortree=2552 /SigmaFactorBS="ttttctttgcttaaattcagcagtgaaaatgccatcctgtcc gacttTATGGTATGATGCTCAATAGaacttgtattataataaatacttgttgatttga a" /listShort="ykuJ, S515, ykuK, ykzF, S516, ykuL, S517, ccpC" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 1484046 /Source="Nicolas_upshifts" /id="U1165" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.48951048951049" /psig=1 /xcortree=2552 /SigmaFactorBS="ttttctttgcttaaattcagcagtgaaaatgccatcctgtcc gacttTATGGTATGATGCTCAATAGaacttgtattataataaatacttgttgatttga a" /listShort="ykuJ, S515, ykuK, ykzF, S516, ykuL, S517, ccpC" /GFF_Attribute="listLong" CDS 1484117..1484356 /gene="ykuJ" /locus_tag="BSU_14100" /old_locus_tag="BSU14100" /function="10.3: tRNA and rRNA base modification" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 16387657, 18436958; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative RNA-specific modification enzyme subunit" /protein_id="NP_389293.1" /db_xref="EnsemblGenomes-Gn:BSU14100" /db_xref="EnsemblGenomes-Tr:CAB13283" /db_xref="InterPro:IPR014904" /db_xref="PDB:2FFG" /db_xref="SubtiList:BG13294" /db_xref="UniProtKB/Swiss-Prot:O34588" /translation="MSQLMGIITRLQSLQETAEAANEPMQRYFEVNGEKICSVKYFEK NQTFELTVFQKGEKPNTYPFDNIDMVSIEIFELLQ*" gene 1484117..1484356 /gene="ykuJ" /locus_tag="BSU_14100" /old_locus_tag="BSU14100" S_feature 1484357..1484465 /Source="Nicolas_S_feature" /locus_tag="new_1484357_1484465" /HighExp="H2O2, LoTm, G135, Paraq, G180, LBGexp, G150, Oxctl, dia0, LPh" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigGF, SigEF, SigA" /TUshortPSig="1, 0.999, 0.997, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S515" CDS 1484466..1484984 /gene="ykuK" /locus_tag="BSU_14110" /old_locus_tag="BSU14110" /function="16.6: Maintain" /function="16.11: Scavenge (Catabolism)" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 16165328, 24464998; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative RNA-binding enzyme component" /protein_id="NP_389294.1" /db_xref="EnsemblGenomes-Gn:BSU14110" /db_xref="EnsemblGenomes-Tr:CAB13284" /db_xref="InterPro:IPR007405" /db_xref="SubtiList:BG13295" /db_xref="UniProtKB/Swiss-Prot:O34776" /translation="MADSFLFYNLSEAQMTFQDVMERLKAFVQKDPRSSYVLSIGTDS QVYRDYTKFITALHLHRTGKGAWGCLKNHTVDRPIHSLREKISLETAYSQETAAHILD GHLMDITDLLLPFTGEGADLTFEVHLDIGKKGLTKDLIQEMTGRITSMGIEAKIKPDS YTAFSYANRFTK*" gene 1484466..1484984 /gene="ykuK" /locus_tag="BSU_14110" /old_locus_tag="BSU14110" promotor_-35 1485021..1485028 /Source="Nicolas_upshift_promotors" /id="U1166" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.946053946053946" /psig=1 /xcortree=454 /SigmaFactorBS="aagccaaggtaaatgtcgaattatgCGGTTGACgtttgttat ctgaTTACTTATTCTAGCGGTAGAgctgaaagtaagttgtcttgctttcagaggtatt c" /listShort="ykzF, S516, ykuL, S517, ccpC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1485042..1485061 /Source="Nicolas_upshift_promotors" /id="U1166" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.946053946053946" /psig=1 /xcortree=454 /SigmaFactorBS="aagccaaggtaaatgtcgaattatgCGGTTGACgtttgttat ctgaTTACTTATTCTAGCGGTAGAgctgaaagtaagttgtcttgctttcagaggtatt c" /listShort="ykzF, S516, ykuL, S517, ccpC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1485056 /Source="Nicolas_upshifts" /id="U1166" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.946053946053946" /psig=1 /xcortree=454 /SigmaFactorBS="aagccaaggtaaatgtcgaattatgCGGTTGACgtttgttat ctgaTTACTTATTCTAGCGGTAGAgctgaaagtaagttgtcttgctttcagaggtatt c" /listShort="ykzF, S516, ykuL, S517, ccpC" /GFF_Attribute="listLong" CDS 1485118..1485315 /gene="abbA" /locus_tag="BSU_14120" /old_locus_tag="BSU14120" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:18840696, 24534728" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 18840696, 24534728; Product type r: regulator" /codon_start=1 /transl_table=11 /product="regulator of AbrB repressor" /protein_id="NP_389295.1" /db_xref="EnsemblGenomes-Gn:BSU14120" /db_xref="EnsemblGenomes-Tr:CAB13285" /db_xref="GOA:O31697" /db_xref="InterPro:IPR025446" /db_xref="PDB:2LZF" /db_xref="SubtiList:BG13334" /db_xref="UniProtKB/Swiss-Prot:O31697" /translation="MRMSLIGERFTEEEQKLLLNILINHEYAIELLSSEINDIETGTK NVDGTTYKKLVTLYDRFRFEN*" gene 1485118..1485315 /gene="abbA" /locus_tag="BSU_14120" /old_locus_tag="BSU14120" downshifts 1485311 /Source="Nicolas_upshifts" /id="D790" /incds=0 /nref=114 /ntot=265 /MaxReadThrough="5.72556" /MaxDrop="4.65809" /score="2.45376472" /energy="-6.8" /TU="U1165,U1166" /idTUdmin="U1162" /TUdmin=12 /isTUend="TRUE" S_feature 1485356..1485452 /Source="Nicolas_S_feature" /locus_tag="new_1485356_1485452" /HighExp="M9-stat, T3.30H, T3.0H, T4.0H, M0t90, T1.0H, T5.0H, T2.30H, T1.30H, M40t90" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.23094000000000001" /TUshortSig="SigA, SigA" /TUshortPSig="1, 1" /TUlongSig="SigGF, SigEF, SigA" /TUlongPSig="0.999, 0.997, 1" /label="S516" CDS 1485453..1485896 /gene="ykuL" /locus_tag="BSU_14130" /old_locus_tag="BSU14130" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 11985717; Product type f: factor" /codon_start=1 /transl_table=11 /product="putative RNA-binding protein" /protein_id="NP_389296.1" /db_xref="EnsemblGenomes-Gn:BSU14130" /db_xref="EnsemblGenomes-Tr:CAB13286" /db_xref="PDB:1YAV" /db_xref="SubtiList:BG13296" /db_xref="UniProtKB/Swiss-Prot:O31698" /translation="MISLQSDQLLEATVGQFMIEADKVAHVQVGNNLEHALLVLTKTG YTAIPVLDPSYRLHGLIGTNMIMNSIFGLERIEFEKLDQITVEEVMLTDIPRLHINDP IMKGFGMVINNGFVCVENDEQVFEGIFTRRVVLKELNKHIRSLNK*" gene 1485453..1485896 /gene="ykuL" /locus_tag="BSU_14130" /old_locus_tag="BSU14130" S_feature 1485897..1486004 /Source="Nicolas_S_feature" /locus_tag="new_1485897_1486004" /HighExp="M0t90, M40t90, M9-stat, T1.0H, T3.30H, T3.0H, T4.0H, S2, T1.30H, T2.30H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="1, 1" /TUlongSig="SigGF, SigEF, SigA" /TUlongPSig="0.999, 0.997, 1" /label="S517" promotor_-35 1485972..1485977 /Source="Nicolas_upshift_promotors" /id="U1167" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.473526473526474" /psig="0.998001998001998" /xcortree=3032 /SigmaFactorBS="catacataatttaaacgagaatagggCTTGAAtaagaaacta agatTTTATTAGAATGGGAGATAAgaaaaacttattgataacaaaaaggaggacgaca t" /listShort="ccpC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1485992..1486011 /Source="Nicolas_upshift_promotors" /id="U1167" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.473526473526474" /psig="0.998001998001998" /xcortree=3032 /SigmaFactorBS="catacataatttaaacgagaatagggCTTGAAtaagaaacta agatTTTATTAGAATGGGAGATAAgaaaaacttattgataacaaaaaggaggacgaca t" /listShort="ccpC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1486006 /Source="Nicolas_upshifts" /id="U1167" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.473526473526474" /psig="0.998001998001998" /xcortree=3032 /SigmaFactorBS="catacataatttaaacgagaatagggCTTGAAtaagaaacta agatTTTATTAGAATGGGAGATAAgaaaaacttattgataacaaaaaggaggacgaca t" /listShort="ccpC" /GFF_Attribute="listLong" CDS 1486045..1486926 /gene="ccpC" /locus_tag="BSU_14140" /old_locus_tag="BSU14140" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:14636591, 16352834, 16395550, 23139400" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 14636591, 16352834, 16395550, 23139400; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional repressor of citB and citZ" /protein_id="NP_389297.1" /db_xref="EnsemblGenomes-Gn:BSU14140" /db_xref="EnsemblGenomes-Tr:CAB13287" /db_xref="GOA:O34827" /db_xref="InterPro:IPR000847" /db_xref="InterPro:IPR005119" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG13297" /db_xref="UniProtKB/Swiss-Prot:O34827" /translation="MQLQELHMLVVLAEELNMRKAAERLFVSQPALSQRLQTIEKAWG TKIFLRSQKGLTVTPAGEKIIQFANDVTLEQERIRENIDELEGEIHGTLKLAVASIIG QHWLPKVLKTYVEKYPNAKISLITGWSSEMLKSLYEDQVHIGIIRGNPEWKGRKDYLM TDHLYLVDTEISCIEDIAHTERPFIQFKSDSTYFQEIQHWWHQKFKTSPKQTILVDQI ETCKQMALHGIGYAILPSVTLQNEDKVNKMPLLDMKGHPIGRDTWLLGYEPAFELKQV QAFVQVIKDMLDQENPF*" gene 1486045..1486926 /gene="ccpC" /locus_tag="BSU_14140" /old_locus_tag="BSU14140" downshifts 1486905 /Source="Nicolas_upshifts" /id="D791" /incds=0 /nref=168 /ntot=242 /MaxReadThrough="1.76921" /MaxDrop="5.2505" /score="37.6563581" /energy="-8.3" /TU="NA" /idTUdmin="U1165" /TUdmin=0 /isTUend="TRUE" promotor_-35 1486961..1486968 /Source="Nicolas_upshift_promotors" /id="U1168" /multdbtbs="SigA" /comp="M17" /sig="SigA" /pcomp="0.614385614385614" /psig=1 /xcortree=2113 /SigmaFactorBS="gacagcgaggtgctgtcttttttttatttatctGTTGACAAt gaaaatcattatcATTTAAAGTGATACATATGAtattgaaaatcattatcaactaatg g" /listShort="ykuN, ykuO, ykuP, dapH, dapL, ykuS" /listLong="S518, S519, ykuU, ykuV" /label="promotor_-35" promotor_-10 1486983..1487002 /Source="Nicolas_upshift_promotors" /id="U1168" /multdbtbs="SigA" /comp="M17" /sig="SigA" /pcomp="0.614385614385614" /psig=1 /xcortree=2113 /SigmaFactorBS="gacagcgaggtgctgtcttttttttatttatctGTTGACAAt gaaaatcattatcATTTAAAGTGATACATATGAtattgaaaatcattatcaactaatg g" /listShort="ykuN, ykuO, ykuP, dapH, dapL, ykuS" /listLong="S518, S519, ykuU, ykuV" /label="promotor_-10" upshifts 1486988 /Source="Nicolas_upshifts" /id="U1168" /multdbtbs="SigA" /comp="M17" /sig="SigA" /pcomp="0.614385614385614" /psig=1 /xcortree=2113 /SigmaFactorBS="gacagcgaggtgctgtcttttttttatttatctGTTGACAAt gaaaatcattatcATTTAAAGTGATACATATGAtattgaaaatcattatcaactaatg g" /listShort="ykuN, ykuO, ykuP, dapH, dapL, ykuS" /listLong="S518, S519, ykuU, ykuV" CDS 1487038..1487514 /gene="fldN" /locus_tag="BSU_14150" /old_locus_tag="BSU14150" /function="16.11: Scavenge (Catabolism)" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:12354229, 15449930, 17127770, 20186410, 21665975, 24214949" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12354229, 15449930, 17127770, 20186410, 21665975, 24214949; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="short-chain flavodoxin (acts in lipid desaturation)" /protein_id="NP_389298.1" /db_xref="EnsemblGenomes-Gn:BSU14150" /db_xref="EnsemblGenomes-Tr:CAB13288" /db_xref="GOA:O34737" /db_xref="InterPro:IPR001094" /db_xref="InterPro:IPR008254" /db_xref="InterPro:IPR010087" /db_xref="InterPro:IPR029039" /db_xref="SubtiList:BG13298" /db_xref="UniProtKB/Swiss-Prot:O34737" /translation="MAKALITYASMSGNTEDIAFIIKDTLQEYELDIDCVEINDMDAS CLTSYDYVLIGTYTWGDGDLPYEAEDFFEEVKQIQLNGLKTACFGSGDYSYPKFCEAV NLFNVMLQEAGAAVYQETLKIELAPETDEDVESCRAFARGFLAWADYMNKEKIHVS*" gene 1487038..1487514 /gene="fldN" /locus_tag="BSU_14150" /old_locus_tag="BSU14150" CDS 1487504..1488397 /gene="ykuO" /locus_tag="BSU_14160" /old_locus_tag="BSU14160" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 12354229, 24214949" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_389299.1" /db_xref="EnsemblGenomes-Gn:BSU14160" /db_xref="EnsemblGenomes-Tr:CAB13289" /db_xref="InterPro:IPR015943" /db_xref="SubtiList:BG13299" /db_xref="UniProtKB/Swiss-Prot:O34879" /translation="MFHKGATAVTASAFSGYFVAVQREGIFHYSLEQGWRKLFRLKSK IHCISYIGPYLFGVGEKGTVIRSADEGKTWTMSSFPTNATVWAITGRNNGFVCAHGKH CIYVSDDFGVSWRVAKPFAEFHNPPVIRSLCLHGGNLFIGTQIHEYFGGIWAYDIKRD TVQVVKKEKNRMTASMLVFNENWLVAAMGSVKGKHGAVTVRNLLNGEEFTIQSSMIRN EESFLDLSEDDGIIYVTTTQDENGFSRIYQVDLEARSLKWFDTIKGHGWRVANQKENF FCAGLYECKFVQPYEVSAMIH*" gene 1487504..1488397 /gene="ykuO" /locus_tag="BSU_14160" /old_locus_tag="BSU14160" CDS 1488413..1488868 /gene="fldP" /locus_tag="BSU_14170" /old_locus_tag="BSU14170" /experiment="publication(s) with functional evidences, PMID:12354229, 15449930, 17127770, 20186410, 21665975, 24214949" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12354229, 15449930, 17127770, 20186410, 21665975, 24214949; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="short-chain flavodoxin" /protein_id="NP_389300.2" /db_xref="EnsemblGenomes-Gn:BSU14170" /db_xref="EnsemblGenomes-Tr:CAB13290" /db_xref="GOA:O34589" /db_xref="InterPro:IPR001094" /db_xref="InterPro:IPR001226" /db_xref="InterPro:IPR008254" /db_xref="InterPro:IPR010087" /db_xref="InterPro:IPR029039" /db_xref="SubtiList:BG13300" /db_xref="UniProtKB/Swiss-Prot:O34589" /translation="MAKILLVYATMSGNTEAMADLIEKGLQEALAEVDRFEAMDIDDA QLFTDYDHVIMGTYTWGDGDLPDEFLDLVEDMEEIDFSGKTCAVFGSGDTAYEFFCGA VDTLEAKIKERGGDIVLPSVKIENNPEGEEEEELINFGRQFAKKSGCAV*" gene 1488413..1488868 /gene="fldP" /locus_tag="BSU_14170" /old_locus_tag="BSU14170" promotor_-10 complement(1488684..1488703) /Source="Nicolas_upshift_promotors" /id="U1169" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.88011988011988" /psig="0.88011988011988" /xcortree=766 /SigmaFactorBS="tccaccgcgttcttttatttttgcctctagcgTATCAACCGc tccgcagaaaaaTTCATATGCTGTATCACCGGaaccgaatacagcgcatgttttgccg g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1488697) /Source="Nicolas_upshifts" /id="U1169" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.88011988011988" /psig="0.88011988011988" /xcortree=766 /SigmaFactorBS="tccaccgcgttcttttatttttgcctctagcgTATCAACCGc tccgcagaaaaaTTCATATGCTGTATCACCGGaaccgaatacagcgcatgttttgccg g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(1488717..1488725) /Source="Nicolas_upshift_promotors" /id="U1169" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.88011988011988" /psig="0.88011988011988" /xcortree=766 /SigmaFactorBS="tccaccgcgttcttttatttttgcctctagcgTATCAACCGc tccgcagaaaaaTTCATATGCTGTATCACCGGaaccgaatacagcgcatgttttgccg g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 1488862 /Source="Nicolas_upshifts" /id="D792" /incds=0 /nref=2 /ntot=54 /MaxReadThrough="6.48855" /MaxDrop="3.75748" /score="20.7202933" /energy="-9" /TU="U1168" /idTUdmin="U1165" /TUdmin=1957 /isTUend="FALSE" promotor_-35 1488907..1488914 /Source="Nicolas_upshift_promotors" /id="U1170" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.49050949050949" /psig=1 /xcortree=2341 /SigmaFactorBS="tcactcactgggaactgctaaaacggctgttcctttttTTCT TGTCtttgtatctttccTTTGATACAGTAATGAGGTAgaaaatcaggaggaggactat a" /listShort="dapH, dapL, ykuS" /listLong="S518, S519, ykuU, ykuV" /label="promotor_-35" promotor_-10 1488928..1488947 /Source="Nicolas_upshift_promotors" /id="U1170" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.49050949050949" /psig=1 /xcortree=2341 /SigmaFactorBS="tcactcactgggaactgctaaaacggctgttcctttttTTCT TGTCtttgtatctttccTTTGATACAGTAATGAGGTAgaaaatcaggaggaggactat a" /listShort="dapH, dapL, ykuS" /listLong="S518, S519, ykuU, ykuV" /label="promotor_-10" upshifts 1488929 /Source="Nicolas_upshifts" /id="U1170" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.49050949050949" /psig=1 /xcortree=2341 /SigmaFactorBS="tcactcactgggaactgctaaaacggctgttcctttttTTCT TGTCtttgtatctttccTTTGATACAGTAATGAGGTAgaaaatcaggaggaggactat a" /listShort="dapH, dapL, ykuS" /listLong="S518, S519, ykuU, ykuV" CDS 1488973..1489683 /gene="dapH" /locus_tag="BSU_14180" /old_locus_tag="BSU14180" /EC_number="2.3.1.89" /function="16.13: Shape" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:5411754, 10368155, 11910040, 12682299, 14627808" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 5411754, 10368155, 11910040, 12682299, 14627808; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="tetrahydrodipicolinate N-acetyltransferase" /protein_id="NP_389301.2" /db_xref="EnsemblGenomes-Gn:BSU14180" /db_xref="EnsemblGenomes-Tr:CAB13291" /db_xref="GOA:O34981" /db_xref="InterPro:IPR001451" /db_xref="InterPro:IPR011004" /db_xref="InterPro:IPR013710" /db_xref="InterPro:IPR016036" /db_xref="InterPro:IPR018357" /db_xref="InterPro:IPR019873" /db_xref="SubtiList:BG13301" /db_xref="UniProtKB/Swiss-Prot:O34981" /translation="MKMMDANEIISFIQNSTKSTPVKVYVKGELEGINFGESAKAFIN GNTGVVFGEWSEIQTAIEENQSKIEDYVVENDRRNSAIPMLDLKNIKARIEPGAIIRD QVEIGDNAVIMMGASINIGSVIGEGTMIDMNVVLGGRATVGKNCHIGAGSVLAGVIEP PSAKPVVIEDDVVIGANAVVLEGVTVGKGAVVAAGAIVVNDVEPYTVVAGTPAKKIKD IDEKTKGKTEIKQELRQL*" gene 1488973..1489683 /gene="dapH" /locus_tag="BSU_14180" /old_locus_tag="BSU14180" downshifts complement(1488982) /Source="Nicolas_upshifts" /id="D793" /incds=0 /nref=60 /ntot=165 /MaxReadThrough="1.03272" /MaxDrop="4.75802" /score="28.9046709" /energy="-15" /TU="NA" /idTUdmin="U1171" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(1489092..1489096) /Source="Nicolas_upshift_promotors" /id="U1171" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.977022977022977" /psig="0.005994005994006" /xcortree=40 /SigmaFactorBS="tgctgtttggatttcgctccattcaccgaaaacgacacCagt gtttccattgataaAAGCTttcgcagattcaccgaaattgattccttccagctcacct t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1489092) /Source="Nicolas_upshifts" /id="U1171" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.977022977022977" /psig="0.005994005994006" /xcortree=40 /SigmaFactorBS="tgctgtttggatttcgctccattcaccgaaaacgacacCagt gtttccattgataaAAGCTttcgcagattcaccgaaattgattccttccagctcacct t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(1489114) /Source="Nicolas_upshift_promotors" /id="U1171" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.977022977022977" /psig="0.005994005994006" /xcortree=40 /SigmaFactorBS="tgctgtttggatttcgctccattcaccgaaaacgacacCagt gtttccattgataaAAGCTttcgcagattcaccgaaattgattccttccagctcacct t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" CDS 1489753..1490877 /gene="dapI" /locus_tag="BSU_14190" /old_locus_tag="BSU14190" /EC_number="3.5.1.47" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:12682299, 14627808, 17093042, 24261876" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12682299, 14627808, 17093042, 24261876; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="N-acetyl-diaminopimelate deacetylase" /protein_id="NP_389302.1" /db_xref="EnsemblGenomes-Gn:BSU14190" /db_xref="EnsemblGenomes-Tr:CAB13292" /db_xref="GOA:O34916" /db_xref="InterPro:IPR002933" /db_xref="InterPro:IPR011650" /db_xref="InterPro:IPR017439" /db_xref="InterPro:IPR023905" /db_xref="InterPro:IPR036264" /db_xref="SubtiList:BG13302" /db_xref="UniProtKB/Swiss-Prot:O34916" /translation="MKIEELIAIRRDLHRIPELGFQEFKTQQYLLNVLEQYPQDRIEI EKWRTGLFVKVNGTAPEKMLAYRADIDALSIEEQTGLPFASEHHGNMHACGHDLHMTI ALGIIDHFVHHPVKHDLLFLFQPAEEGPGGAEPMLESDVLKKWQPDFITALHIAPELP VGTIATKSGLLFANTSELVIDLEGKGGHAAYPHLAEDMVVAASTLVTQLQTIISRNTD PLDSAVITVGTITGGSAQNIIAETAHLEGTIRTLSEESMKQVKERIEDVVKGIEIGFR CKGKVTYPSVYHQVYNTSGLTEEFMSFVAEHQLATVIEAKEAMTGEDFGYMLKKYPGF MFWLGADSEHGLHHAKLNPDENAIETAVHVMTGYFSVYAN*" gene 1489753..1490877 /gene="dapI" /locus_tag="BSU_14190" /old_locus_tag="BSU14190" promotor_-35 1490889..1490895 /Source="Nicolas_upshift_promotors" /id="U1172" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=883 /SigmaFactorBS="ggttatttttctgtttatgccaattaagtacaaatgaaAGAA TAAaattccataaaatGAGCACTCTAGTaaacggaggtgttcaaaaatggctaaaaaa a" /listShort="ykuS, S518, S519, ykuU, ykuV" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1490909..1490920 /Source="Nicolas_upshift_promotors" /id="U1172" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=883 /SigmaFactorBS="ggttatttttctgtttatgccaattaagtacaaatgaaAGAA TAAaattccataaaatGAGCACTCTAGTaaacggaggtgttcaaaaatggctaaaaaa a" /listShort="ykuS, S518, S519, ykuU, ykuV" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1490911 /Source="Nicolas_upshifts" /id="U1172" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=883 /SigmaFactorBS="ggttatttttctgtttatgccaattaagtacaaatgaaAGAA TAAaattccataaaatGAGCACTCTAGTaaacggaggtgttcaaaaatggctaaaaaa a" /listShort="ykuS, S518, S519, ykuU, ykuV" /GFF_Attribute="listLong" promotor_-10 complement(1490915..1490929) /Source="Nicolas_upshift_promotors" /id="U1173" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp=1 /psig=0 /xcortree=701 /SigmaFactorBS="ttttcttttaaagcagcttctacatctgataacgattgttca attccaatttttttaGCCATttttgaacaCCTCCGTTTACTAGAgtgctcattttatg g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 complement(1490939..1490943) /Source="Nicolas_upshift_promotors" /id="U1173" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp=1 /psig=0 /xcortree=701 /SigmaFactorBS="ttttcttttaaagcagcttctacatctgataacgattgttca attccaatttttttaGCCATttttgaacaCCTCCGTTTACTAGAgtgctcattttatg g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" CDS 1490939..1491184 /gene="ykuS" /locus_tag="BSU_14200" /old_locus_tag="BSU14200" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_389303.1" /db_xref="EnsemblGenomes-Gn:BSU14200" /db_xref="EnsemblGenomes-Tr:CAB13293" /db_xref="InterPro:IPR005370" /db_xref="SubtiList:BG13303" /db_xref="UniProtKB/Swiss-Prot:O34783" /translation="MAKKIGIEQSLSDVEAALKEKGYDVVMMKSPADAQGCDCCVVTG LDNNVQGIADTVTQAPVITASGMTAEEICSEVESRIQ*" gene 1490939..1491184 /gene="ykuS" /locus_tag="BSU_14200" /old_locus_tag="BSU14200" upshifts complement(1490940) /Source="Nicolas_upshifts" /id="U1173" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp=1 /psig=0 /xcortree=701 /SigmaFactorBS="ttttcttttaaagcagcttctacatctgataacgattgttca attccaatttttttaGCCATttttgaacaCCTCCGTTTACTAGAgtgctcattttatg g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" downshifts 1491172 /Source="Nicolas_upshifts" /id="D794" /incds=0 /nref=238 /ntot=269 /MaxReadThrough="3.49553" /MaxDrop="5.88829" /score="3.56597112" /energy="-9.9" /TU="U1172" /idTUdmin="U1168" /TUdmin=0 /isTUend="TRUE" S_feature 1491217..1492167 /Source="Nicolas_S_feature" /locus_tag="new_1491217_1492167" /HighExp="S4, S5, S6, S3, S7, S8, LoTm, BT, B36, G135" /AntisenseName="ykuT" /AntisenseCor="-0.479447808227356" /AntisenseRegPval="-16.100000000000001" /CDS_PredictionProba="NA" /TUshortSig="SigGF" /TUshortPSig=1 /TUlongSig="SigA, SigA" /TUlongPSig="1, 1" /label="S518" CDS complement(1491221..1492024) /gene="mscT" /locus_tag="BSU_14210" /old_locus_tag="BSU14210" /function="16.6: Maintain" /function="16.8: Protect" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:12626684, 17665170, 18310427, 19252899, 21150093" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12626684, 17665170, 18310427, 19252899, 21150093; Product type t : transporter" /codon_start=1 /transl_table=11 /product="small-conductance mechanosensitive channel" /protein_id="NP_389304.2" /db_xref="EnsemblGenomes-Gn:BSU14210" /db_xref="EnsemblGenomes-Tr:CAB13294" /db_xref="GOA:O34897" /db_xref="InterPro:IPR006685" /db_xref="InterPro:IPR010920" /db_xref="InterPro:IPR011014" /db_xref="InterPro:IPR011066" /db_xref="SubtiList:BG13304" /db_xref="UniProtKB/Swiss-Prot:O34897" /translation="MDFIKQYDWAGLITNAGVLLIKLAIMILLYFIVRSLGMKIIKHL FAKFEEQNSLSIGRAHTLRSLTLNIFAYTLIFIFFVMVLDLFHYDPSALLAGAGIVGL AVGFGAQGLVSDIVTGFFILLEKQLDVGDYITVSTFDGIVEQVGLRTTQIRSFDGTLH YIPNRNITNVSNHSRGTMQALVDIKVPAERNIDEMIHILQQVCDETAAALPQIKEGPN VIGIQELGTSEIVIRVIAKTENMEQWRVERVLRKEIKNAFDRAFPKETE*" gene complement(1491221..1492024) /gene="mscT" /locus_tag="BSU_14210" /old_locus_tag="BSU14210" downshifts complement(1491233) /Source="Nicolas_upshifts" /id="D795" /incds=0 /nref=16 /ntot=131 /MaxReadThrough="1.65551" /MaxDrop="4.4361" /score="29.0050313" /energy="-9.9" /TU="NA" /idTUdmin="U1174" /TUdmin="-7" /isTUend="TRUE" promotor_-10 complement(1492075..1492094) /Source="Nicolas_upshift_promotors" /id="U1174" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.892107892107892" /psig="0.975024975024975" /xcortree=2730 /SigmaFactorBS="caatttttaacaaatcatgtatgtctttgGCTTCGACatttt tgaataaaACGTTTAACATGGTCATGTAcagggtaactagtctcaatgtgcagcaatc a" /listShort="ykuT" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1492084) /Source="Nicolas_upshifts" /id="U1174" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.892107892107892" /psig="0.975024975024975" /xcortree=2730 /SigmaFactorBS="caatttttaacaaatcatgtatgtctttgGCTTCGACatttt tgaataaaACGTTTAACATGGTCATGTAcagggtaactagtctcaatgtgcagcaatc a" /listShort="ykuT" /GFF_Attribute="listLong" promotor_-35 complement(1492108..1492115) /Source="Nicolas_upshift_promotors" /id="U1174" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.892107892107892" /psig="0.975024975024975" /xcortree=2730 /SigmaFactorBS="caatttttaacaaatcatgtatgtctttgGCTTCGACatttt tgaataaaACGTTTAACATGGTCATGTAcagggtaactagtctcaatgtgcagcaatc a" /listShort="ykuT" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1492140..1492147 /Source="Nicolas_upshift_promotors" /id="U1175" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.849150849150849" /psig="0.999000999001" /xcortree=3170 /SigmaFactorBS="tcgaagccaaagacatacatgatttgttaaaAATTGACTcag gaaatctgcttTTATATAATGGCATTGCAATataactaaaaatggttaatcacccttt a" /listShort="S519, ykuU, ykuV" /listLong="rok" /label="promotor_-35" promotor_-10 1492162..1492181 /Source="Nicolas_upshift_promotors" /id="U1175" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.849150849150849" /psig="0.999000999001" /xcortree=3170 /SigmaFactorBS="tcgaagccaaagacatacatgatttgttaaaAATTGACTcag gaaatctgcttTTATATAATGGCATTGCAATataactaaaaatggttaatcacccttt a" /listShort="S519, ykuU, ykuV" /listLong="rok" /label="promotor_-10" S_feature 1492169..1492260 /Source="Nicolas_S_feature" /locus_tag="new_1492169_1492260" /HighExp="LPhT, Salt, Etha, M9-stat, M0t90, T4.0H, T5.0H, S4, Heat, Lbstat" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigGF" /TUshortPSig="0.999, 1" /TUlongSig="SigA, SigA" /TUlongPSig="1, 1" /label="S519" upshifts 1492169 /Source="Nicolas_upshifts" /id="U1175" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.849150849150849" /psig="0.999000999001" /xcortree=3170 /SigmaFactorBS="tcgaagccaaagacatacatgatttgttaaaAATTGACTcag gaaatctgcttTTATATAATGGCATTGCAATataactaaaaatggttaatcacccttt a" /listShort="S519, ykuU, ykuV" /listLong="rok" CDS 1492261..1492803 /gene="ahpA" /locus_tag="BSU_14220" /old_locus_tag="BSU14220" /EC_number="1.11.1.-" /function="16.6: Maintain" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:22938038, 27683249" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 22938038, 27683249; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="biofilm-specific peroxidase; 2-cys peroxiredoxin" /protein_id="NP_389305.1" /db_xref="EnsemblGenomes-Gn:BSU14220" /db_xref="EnsemblGenomes-Tr:CAB13295" /db_xref="GOA:O34564" /db_xref="InterPro:IPR000866" /db_xref="InterPro:IPR013766" /db_xref="InterPro:IPR019479" /db_xref="InterPro:IPR024706" /db_xref="InterPro:IPR036249" /db_xref="SubtiList:BG13305" /db_xref="UniProtKB/Swiss-Prot:O34564" /translation="MAERMVGKQAPRFEMEAVLASKEFGKVSLEENMKNDKWTVLFFY PMDFTFVCPTEITAMSDRYDEFEDLDAEVIGVSTDTIHTHLAWINTDRKENGLGQLKY PLAADTNHEVSREYGVLIEEEGVALRGLFIINPEGELQYQTVFHNNIGRDVDETLRVL QALQTGGLCPANWKPGQKTL*" gene 1492261..1492803 /gene="ahpA" /locus_tag="BSU_14220" /old_locus_tag="BSU14220" CDS 1492875..1493321 /gene="ykuV" /locus_tag="BSU_14230" /old_locus_tag="BSU14230" /EC_number="1.8.-.-" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:15937154, 16132829, 16418167" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15937154, 16132829, 16418167; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="thiol-disulfide oxidoreductase" /protein_id="NP_389306.2" /db_xref="EnsemblGenomes-Gn:BSU14230" /db_xref="EnsemblGenomes-Tr:CAB13296" /db_xref="GOA:O31699" /db_xref="InterPro:IPR000866" /db_xref="InterPro:IPR013766" /db_xref="InterPro:IPR036249" /db_xref="PDB:2B5X" /db_xref="PDB:2B5Y" /db_xref="SubtiList:BG13306" /db_xref="UniProtKB/Swiss-Prot:O31699" /translation="MKLRQPMPELTGEKAWLNGEVTREQLIGEKPTLIHFWSISCHLC KEAMPQVNEFRDKYQDQLNVVAVHMPRSEDDLDPGKIKETAAEHDITQPIFVDSDHAL TDAFENEYVPAYYVFDKTGQLRHFQAGGSGMKMLEKRVNRVLAETE*" gene 1492875..1493321 /gene="ykuV" /locus_tag="BSU_14230" /old_locus_tag="BSU14230" downshifts 1493329 /Source="Nicolas_upshifts" /id="D796" /incds=0 /nref=58 /ntot=211 /MaxReadThrough="3.11112" /MaxDrop="4.73023" /score="10.8864177" /energy="-5.4" /TU="U1175" /idTUdmin="U1172" /TUdmin=0 /isTUend="TRUE" promotor_-35 1493714..1493721 /Source="Nicolas_upshift_promotors" /id="U1176" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.884115884115884" /psig=1 /xcortree=2393 /SigmaFactorBS="ttttcatagagtaaatataatagtaaaatgctaaaataatAG TTGATAaaattacttttgtaATCTAATATCTTAATTAAAGatgttaattttgataggg g" /listShort="rok" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 1493734 /Source="Nicolas_upshifts" /id="U1176" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.884115884115884" /psig=1 /xcortree=2393 /SigmaFactorBS="ttttcatagagtaaatataatagtaaaatgctaaaataatAG TTGATAaaattacttttgtaATCTAATATCTTAATTAAAGatgttaattttgataggg g" /listShort="rok" /GFF_Attribute="listLong" promotor_-10 1493736..1493755 /Source="Nicolas_upshift_promotors" /id="U1176" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.884115884115884" /psig=1 /xcortree=2393 /SigmaFactorBS="ttttcatagagtaaatataatagtaaaatgctaaaataatAG TTGATAaaattacttttgtaATCTAATATCTTAATTAAAGatgttaattttgataggg g" /listShort="rok" /GFF_Attribute="listLong" /label="promotor_-10" CDS 1493787..1494362 /gene="rok" /locus_tag="BSU_14240" /old_locus_tag="BSU14240" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:15743949, 15819619, 27902860" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15743949, 15819619, 27902860; Product type r: regulator" /codon_start=1 /transl_table=11 /product="repressor of comK" /protein_id="NP_389307.1" /db_xref="EnsemblGenomes-Gn:BSU14240" /db_xref="EnsemblGenomes-Tr:CAB13297" /db_xref="GOA:O34857" /db_xref="SubtiList:BG13307" /db_xref="UniProtKB/Swiss-Prot:O34857" /translation="MFNEREALRLRLEQLNEAEVKVIREYQIERDKIYAKLRELDRNG SPSEIKKDFRSEKKPDSLPVLAELAAQEIRSYQPQSQQQSVQPQLQSISSLPAGIPDG TTRRRRGTARPGSKAAKLREAAIKTLKRHNAAIKSSELQKEIEKESGLEIPNMTTFMQ SLIKMYPEVKKPYRGQYILEGEIESAESANE*" gene 1493787..1494362 /gene="rok" /locus_tag="BSU_14240" /old_locus_tag="BSU14240" downshifts 1494340 /Source="Nicolas_upshifts" /id="D797" /incds=0 /nref=246 /ntot=258 /MaxReadThrough="1.77207" /MaxDrop="6.35121" /score="17.7584572" /energy="-9" /TU="NA" /idTUdmin="U1176" /TUdmin=0 /isTUend="TRUE" CDS complement(1494403..1495368) /gene="sppO" /locus_tag="BSU_14250" /old_locus_tag="BSU14250" /experiment="publication(s) with functional evidences, PMID:8990290, 15383836, 15743949" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8990290, 15383836, 15743949; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="spore protein cse15" /protein_id="NP_389308.1" /db_xref="EnsemblGenomes-Gn:BSU14250" /db_xref="EnsemblGenomes-Tr:CAB13298" /db_xref="GOA:O31700" /db_xref="SubtiList:BG12251" /db_xref="UniProtKB/Swiss-Prot:O31700" /translation="MKRSGPFFHDVSQENLYLKSELSRCHKLISELEASYFHQKNNKL LKENTDMKEKLQQLSAELTHMSTKEKHASHTSQTLHQIRAELLDKIVVLQELLSAETY KRRAEIEEKHKLHIAKVKIEEENKNLHKRISELQASIEQEQNALLQAKQQAELIKAEN GRLKEQMVEKEYQLKHIKIEVDHMKDRIIETKERLLDIEKTKEKLFHETIISYKRQLD ESDAWIASHFADIDGGTKQKEKTEEEAPAAYAQPNHVETILEDVTKQIHVLQKQLAHA QSSDQAKSHTIEELKNRAAEEKPYQKWVYKLNLEKENKPSQKKPQ*" gene complement(1494403..1495368) /gene="sppO" /locus_tag="BSU_14250" /old_locus_tag="BSU14250" downshifts complement(1494416) /Source="Nicolas_upshifts" /id="D798" /incds=0 /nref=47 /ntot=67 /MaxReadThrough="2.24884" /MaxDrop="5.5936" /score="3.60334458" /energy="-7.2" /TU="NA" /idTUdmin="U1178" /TUdmin=0 /isTUend="TRUE" promotor_-35 1494712..1494713 /Source="Nicolas_upshift_promotors" /id="U1177" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.547452547452547" /psig="0.988011988011988" /xcortree=1801 /SigmaFactorBS="atatcggcaaaatgagaagcaatccaggcatcgctTTcatca agttgccgtttaTACGATATAATAGTTTCGTGaaataatttttctttcgttttttcta t" /listShort="S520, mobA, moeB, moeA, mobB, moaE, moaD" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1494731..1494750 /Source="Nicolas_upshift_promotors" /id="U1177" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.547452547452547" /psig="0.988011988011988" /xcortree=1801 /SigmaFactorBS="atatcggcaaaatgagaagcaatccaggcatcgctTTcatca agttgccgtttaTACGATATAATAGTTTCGTGaaataatttttctttcgttttttcta t" /listShort="S520, mobA, moeB, moeA, mobB, moaE, moaD" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 1494737..1495461 /Source="Nicolas_S_feature" /locus_tag="new_1494737_1495461" /HighExp="dia15, Diami, dia5, H2O2, G135, G150, G180, LBGexp, Paraq, Lbexp" /AntisenseName="yknT" /AntisenseCor="-0.36512493899072102" /AntisenseRegPval="-9.1999999999999993" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.988" /TUlongSig="NA" /TUlongPSig="NA" /label="S520" upshifts 1494737 /Source="Nicolas_upshifts" /id="U1177" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.547452547452547" /psig="0.988011988011988" /xcortree=1801 /SigmaFactorBS="atatcggcaaaatgagaagcaatccaggcatcgctTTcatca agttgccgtttaTACGATATAATAGTTTCGTGaaataatttttctttcgttttttcta t" /listShort="S520, mobA, moeB, moeA, mobB, moaE, moaD" /GFF_Attribute="listLong" promotor_-10 complement(1495389..1495407) /Source="Nicolas_upshift_promotors" /id="U1178" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp="0.995004995004995" /psig="0.995004995004995" /xcortree=1151 /SigmaFactorBS="aaaagcaaaggctcaacgctactgcttgtctgtttattaaag aGGAATAgctgttcagtatttGCATATTGTAGTGTTAACAtcatgagggagatggttc g" /listShort="yknT" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1495410) /Source="Nicolas_upshifts" /id="U1178" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp="0.995004995004995" /psig="0.995004995004995" /xcortree=1151 /SigmaFactorBS="aaaagcaaaggctcaacgctactgcttgtctgtttattaaag aGGAATAgctgttcagtatttGCATATTGTAGTGTTAACAtcatgagggagatggttc g" /listShort="yknT" /GFF_Attribute="listLong" promotor_-35 complement(1495422..1495427) /Source="Nicolas_upshift_promotors" /id="U1178" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp="0.995004995004995" /psig="0.995004995004995" /xcortree=1151 /SigmaFactorBS="aaaagcaaaggctcaacgctactgcttgtctgtttattaaag aGGAATAgctgttcagtatttGCATATTGTAGTGTTAACAtcatgagggagatggttc g" /listShort="yknT" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1495448..1495454 /Source="Nicolas_upshift_promotors" /id="U1179" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.442557442557443" /psig="0.99000999000999" /xcortree=2673 /SigmaFactorBS="atgcaaatactgaacagctattcctctttaataaacagacaa gcAGTAGCGttgagcctttgctTTTGCTATGCTTTTAACGAAactagaggtgagatga t" /listShort="mobA, moeB, moeA, mobB, moaE, moaD" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 1495464 /Source="Nicolas_upshifts" /id="U1179" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.442557442557443" /psig="0.99000999000999" /xcortree=2673 /SigmaFactorBS="atgcaaatactgaacagctattcctctttaataaacagacaa gcAGTAGCGttgagcctttgctTTTGCTATGCTTTTAACGAAactagaggtgagatga t" /listShort="mobA, moeB, moeA, mobB, moaE, moaD" /GFF_Attribute="listLong" promotor_-10 1495468..1495487 /Source="Nicolas_upshift_promotors" /id="U1179" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.442557442557443" /psig="0.99000999000999" /xcortree=2673 /SigmaFactorBS="atgcaaatactgaacagctattcctctttaataaacagacaa gcAGTAGCGttgagcctttgctTTTGCTATGCTTTTAACGAAactagaggtgagatga t" /listShort="mobA, moeB, moeA, mobB, moaE, moaD" /GFF_Attribute="listLong" /label="promotor_-10" CDS 1495505..1496104 /gene="mobA" /locus_tag="BSU_14260" /old_locus_tag="BSU14260" /EC_number="2.7.7.77" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 10978347; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="molybdopterin-guanine dinucleotide biosynthesis protein A" /protein_id="NP_389309.1" /db_xref="EnsemblGenomes-Gn:BSU14260" /db_xref="EnsemblGenomes-Tr:CAB13299" /db_xref="GOA:O31701" /db_xref="InterPro:IPR013482" /db_xref="InterPro:IPR025877" /db_xref="InterPro:IPR029044" /db_xref="SubtiList:BG12621" /db_xref="UniProtKB/Swiss-Prot:O31701" /translation="MKHVNVLLAGGASRRFGEPKAFVKWKGRMLYECAKEALGEQTVI ISRPEFIDRFQENGENEVYQDAEPFQGMGPLAGIYTAFKKTDGDLYTVLSCDTPLIQR RTMLELKRLMIAGADAVVPISDGQVQPLIAIYHKRIMPVLYDQLSEKRLRISDLLGRI SVCYVQAENIGANPAEFININTRDDFSCLEEKSNSLKRD*" gene 1495505..1496104 /gene="mobA" /locus_tag="BSU_14260" /old_locus_tag="BSU14260" CDS 1496155..1497174 /gene="moeB" /locus_tag="BSU_14270" /old_locus_tag="BSU14270" /EC_number="2.7.7.80" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2b: Function from indirect experimental evidences (e.g. phenotypes); PubMedId: 17223713; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="molybdopterin biosynthesis adenylyltransferase" /protein_id="NP_389310.1" /db_xref="EnsemblGenomes-Gn:BSU14270" /db_xref="EnsemblGenomes-Tr:CAB13300" /db_xref="GOA:O31702" /db_xref="InterPro:IPR000594" /db_xref="InterPro:IPR035985" /db_xref="SubtiList:BG12624" /db_xref="UniProtKB/Swiss-Prot:O31702" /translation="MEERYSRQIRFKQIGEEGQKRLADSHVLIVGAGALGTAGAEGLS RAGVGTITIIDRDYVEWSNLQRQQLYTESDAKLRMPKAMAAKEHLSAINSEIHIEAYV TEGTAETLEPLIEKADVVIDATDNFETRMLINDLAQKTKTPWVYGACVSSQGMFMTVI PGETPCLSCLFEQIPVGGATCDTAGIIPPAVHIVSAYQQAEALKLLTGQKEAIQRGFV TFDVWNNSHMKINVNHVRREECPSCGANAVYPYLQDWNTPKAAVLCGRDTVQVRSESL KRIPKQELIKRLKTIGKVEANAFLLHIFYEDFRIVIFNDGRALVHGTNDVKEANSVLA RVIGL*" gene 1496155..1497174 /gene="moeB" /locus_tag="BSU_14270" /old_locus_tag="BSU14270" CDS 1497192..1498484 /gene="moeA" /locus_tag="BSU_14280" /old_locus_tag="BSU14280" /EC_number="2.10.1.1" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2b: Function from indirect experimental evidences (e.g. phenotypes); PubMedId: 11428898, 12006571, 18959753, 21206014; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="molybdate to molybdopterin ligation enzyme" /protein_id="NP_389311.1" /db_xref="EnsemblGenomes-Gn:BSU14280" /db_xref="EnsemblGenomes-Tr:CAB13301" /db_xref="GOA:O31703" /db_xref="InterPro:IPR001453" /db_xref="InterPro:IPR005110" /db_xref="InterPro:IPR005111" /db_xref="InterPro:IPR036135" /db_xref="InterPro:IPR036425" /db_xref="InterPro:IPR036688" /db_xref="SubtiList:BG12623" /db_xref="UniProtKB/Swiss-Prot:O31703" /translation="MLEKRTPIPVDEAVRRVCHFQKQGETEWVALEDSLHRFLAEDIT ADHHVPAFDRSPYDGFAVRACDTAEASRENPVRFEVIDHIGAGAVSEKELGPFQAVRI MTGAQIPEGADAVVMIELTQAFEENGKSFMSLKRRFQTGDNISKTGEDAQKGSVLLTK GTRVTPGVTALLATFGYASVPVVRKPVVGIIATGTELLNVSDPLEPGKIRNSNASMVY AQAIEAGATPLYLGKISDELDKSFAAVKEAMKKVDFLITTGGVSVGDFDFLPAIYEKL GADVLFNKVAMRPGSVTTVAHANDMLLFGLSGNPSACYVGFELFVKPIIQTWLLNETP HSICAEAVLTKDFPKPNPFTRFVRALVHHQEGKLLATPVGLDKSSSVTSLADANAFII LPGGTRGYESGRTVQVLLIREENGSEWPWSVLSRSSKL*" gene 1497192..1498484 /gene="moeA" /locus_tag="BSU_14280" /old_locus_tag="BSU14280" CDS 1498445..1498966 /gene="mobB" /locus_tag="BSU_14290" /old_locus_tag="BSU14290" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2b: Function from indirect experimental evidences (e.g. phenotypes); PubMedId: 9219527, 12682065, 12719427; Product type c: carrier" /codon_start=1 /transl_table=11 /product="molybdopterin-guanine dinucleotide biosynthesis protein B" /protein_id="NP_389312.1" /db_xref="EnsemblGenomes-Gn:BSU14290" /db_xref="EnsemblGenomes-Tr:CAB13302" /db_xref="GOA:O31704" /db_xref="InterPro:IPR004435" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG12622" /db_xref="UniProtKB/Swiss-Prot:O31704" /translation="MALVRPFPIVQVVGFQNSGKTTFIERILEKASEQGVHLGCLKHH GHGGEPQTLTEGKDTDRYKAAGADVTAVEGAGVLQLTARRNWDLARLIELYQFLETDC LLIEGFKKAPYPKVVILSEKEDLEALQAVNIIAIIYRKKEHMTEHQGLPVFHADDPVA VDFVLSQLKGESA*" gene 1498445..1498966 /gene="mobB" /locus_tag="BSU_14290" /old_locus_tag="BSU14290" CDS 1498966..1499439 /gene="moaE" /locus_tag="BSU_14300" /old_locus_tag="BSU14300" /EC_number="2.8.1.12" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2b: Function from indirect experimental evidences (e.g. phenotypes); PubMedId: 11135669, 18092812; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="molybdopterin synthase (large subunit)" /protein_id="NP_389313.1" /db_xref="EnsemblGenomes-Gn:BSU14300" /db_xref="EnsemblGenomes-Tr:CAB13303" /db_xref="GOA:O31705" /db_xref="InterPro:IPR003448" /db_xref="InterPro:IPR036563" /db_xref="SubtiList:BG12620" /db_xref="UniProtKB/Swiss-Prot:O31705" /translation="MERFEITKTPINTENIIKKVEKREAGAITTFIGTVREWTNGKRT VRLEYEAYEPMAVQMLAQIGAEIEEKWEGASAAITHRIGVLDIGEAAVVIAVSSPHRK AAYEANEYAIERIKQIVPIWKKEIWEDGEQWIGDQLETTAYPNGKPDLSEGEQHD*" gene 1498966..1499439 /gene="moaE" /locus_tag="BSU_14300" /old_locus_tag="BSU14300" CDS 1499432..1499665 /gene="moaD" /locus_tag="BSU_14310" /old_locus_tag="BSU14310" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2b: Function from indirect experimental evidences (e.g. phenotypes); PubMedId: 11135669, 17223713, 19946146; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="molybdopterin synthase (small subunit)" /protein_id="NP_389314.1" /db_xref="EnsemblGenomes-Gn:BSU14310" /db_xref="EnsemblGenomes-Tr:CAB13304" /db_xref="GOA:O31706" /db_xref="InterPro:IPR003749" /db_xref="InterPro:IPR010034" /db_xref="InterPro:IPR012675" /db_xref="InterPro:IPR016155" /db_xref="SubtiList:BG12619" /db_xref="UniProtKB/Swiss-Prot:O31706" /translation="MIKILLFAGLAEQAGTQAIEIDMEQATTDEIKASLKEQYGLESI DTAMIAVNESYVKENTSVSSGDTVAIIPPVSGG*" gene 1499432..1499665 /gene="moaD" /locus_tag="BSU_14310" /old_locus_tag="BSU14310" downshifts 1499644 /Source="Nicolas_upshifts" /id="D799" /incds=0 /nref=87 /ntot=240 /MaxReadThrough="1.14308" /MaxDrop="5.73073" /score="32.0123217" /energy="-16.9" /TU="NA" /idTUdmin="U1177" /TUdmin=2 /isTUend="TRUE" promotor_-35 1499710..1499715 /Source="Nicolas_upshift_promotors" /id="U1180" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=954 /SigmaFactorBS="ttcagccgtccggtttttctgtatttcattGGCATAtcccca agtatcctcaGCATACAATGATTTTCTGTaagcgtttattctacatatgttactccct a" /listShort="S521, yknU, yknV" /listLong="yknW, yknX, yknY, yknZ" /label="promotor_-35" promotor_-10 1499732..1499750 /Source="Nicolas_upshift_promotors" /id="U1180" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=954 /SigmaFactorBS="ttcagccgtccggtttttctgtatttcattGGCATAtcccca agtatcctcaGCATACAATGATTTTCTGTaagcgtttattctacatatgttactccct a" /listShort="S521, yknU, yknV" /listLong="yknW, yknX, yknY, yknZ" /label="promotor_-10" upshifts 1499740 /Source="Nicolas_upshifts" /id="U1180" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=954 /SigmaFactorBS="ttcagccgtccggtttttctgtatttcattGGCATAtcccca agtatcctcaGCATACAATGATTTTCTGTaagcgtttattctacatatgttactccct a" /listShort="S521, yknU, yknV" /listLong="yknW, yknX, yknY, yknZ" S_feature 1499752..1499838 /Source="Nicolas_S_feature" /locus_tag="new_1499752_1499838" /HighExp="S4, S5, S3, T5.0H, T4.0H, Pyr, S6, T3.30H, M9-stat, G/S" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigEF" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S521" promotor_-35 1499828..1499831 /Source="Nicolas_upshift_promotors" /id="U1181" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.525474525474525" /psig="0.987012987012987" /xcortree=406 /SigmaFactorBS="ataaagtaagagactcactccataattagactgaaattttga aaaataATAGaaatttatttcgggTATCGATATAGTGAAGATGAtaaatgttggaaag g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 1499840 /Source="Nicolas_upshifts" /id="U1181" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.525474525474525" /psig="0.987012987012987" /xcortree=406 /SigmaFactorBS="ataaagtaagagactcactccataattagactgaaattttga aaaataATAGaaatttatttcgggTATCGATATAGTGAAGATGAtaaatgttggaaag g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 1499846..1499865 /Source="Nicolas_upshift_promotors" /id="U1181" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.525474525474525" /psig="0.987012987012987" /xcortree=406 /SigmaFactorBS="ataaagtaagagactcactccataattagactgaaattttga aaaataATAGaaatttatttcgggTATCGATATAGTGAAGATGAtaaatgttggaaag g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" CDS 1499889..1501646 /gene="yknU" /locus_tag="BSU_14320" /old_locus_tag="BSU14320" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative ABC transporter (ATP-binding protein)" /protein_id="NP_389315.1" /db_xref="EnsemblGenomes-Gn:BSU14320" /db_xref="EnsemblGenomes-Tr:CAB13305" /db_xref="GOA:O31707" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR011527" /db_xref="InterPro:IPR017871" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR036640" /db_xref="SubtiList:BG13241" /db_xref="UniProtKB/Swiss-Prot:O31707" /translation="METFKRLKMYYWPYRKVFMWSLLAMLLMTAITVVYPIILQITID EIVLGRQYQLAAWVSLGFIAVMVLKGMATFFHQYLGDMFGIKSVYRLRNGLYEKLQRL SFSYYDNAKTGDLMSRLTADVEGLRFFLSYGLAELIRFGLLVAISLSVMFYYSVPLTL VTIAVLPFLAVAVYRFDKRVHPAFRGIRKSFAKLNTKVQENISGINTVKSLSREDFQI STFNKANAEYRAQYLQTSSIWSAYFPLMEFIGNTCIVALLSYGGYLVMQNQLNPGELV AFFSLVNYMMWPIMNLGFVINMFSQAKASGERLLDILEKEEDITDHPHALHKQKLTGD VHFKNVSLAYGKEQTNALCNVSFEANSGKVIGLLGPTGSGKSSVTQLLTRFYSPVGGM ITIDHKPITDYSLKTLRSNIGVVLQESFLFSSTIRSNISYGRPDASMEDVIEAAKRAQ AHNFIMELPDGYDTMLGERGMGLSGGQKQRIAIARAICLNPSILILDDATSAVDMQTE HSIQLALKEVMKNRTTFIVAHRISSLKHADEILVFNKGRIRERGTHHELLEKGGYYKK IYDLQYRDVKMINEPHEVG*" gene 1499889..1501646 /gene="yknU" /locus_tag="BSU_14320" /old_locus_tag="BSU14320" CDS 1501658..1503472 /gene="yknV" /locus_tag="BSU_14330" /old_locus_tag="BSU14330" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative ABC transporter (ATP-binding protein)" /protein_id="NP_389316.1" /db_xref="EnsemblGenomes-Gn:BSU14330" /db_xref="EnsemblGenomes-Tr:CAB13306" /db_xref="GOA:O31708" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR011527" /db_xref="InterPro:IPR017871" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR036640" /db_xref="SubtiList:BG13242" /db_xref="UniProtKB/Swiss-Prot:O31708" /translation="MKQAKKQGVLERFYYSSDEIIEKPFNWAQMWRLLSYVKPYRKTI LPLSFLTVLIGTAVKLVIPILIGVYVLDQAITGRNSELLIQLIFIISGLYVLNYAANV LRIRWMNQLGQHVIYDLRQHLFTHVQRLSHRFFDQRSAGSILVRIMNDINSLQELFTS GVINLLTDLLLLAGVIIILFTLSPELTIAIMVTLPIMFFISTSLRKKIRRSWQTVRLK QSKLNSHLNESIQGIRVTQAFTQEEENMAYFDGVNQENYESWREATRKNAMFRPLVEM TNAIGTAVLIWYGATLIMNETITIGVFVSFAFYLGMFWEPISRLGQVYNQLLMGMASS ERIFEFLDEQPNVKEKPNAIHNEKINGEISFEEVEFSYDEKRKALHAVSFSIPAGSTL ALVGHTGSGKTTIANLISRFYDAAGGTIKIDGIPIKDLSLASLRSQISIVLQDTFIFS GTIMENIRFGRPNASDEEVMKASQAVGADEFISDLAEGYATEVEERGSVLSAGQRQLI SFARALLADPAIIILDEATASIDTETEVKIQQALKTLLKGRTAVMIAHRLSTIRDADR IIVLDHGRKIEEGNHDQLLAKGGIYAGLVKAQYSTAIE*" gene 1501658..1503472 /gene="yknV" /locus_tag="BSU_14330" /old_locus_tag="BSU14330" promotor_-10 complement(1502095..1502114) /Source="Nicolas_upshift_promotors" /id="U1182" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.63036963036963" /psig="0.954045954045954" /xcortree=1712 /SigmaFactorBS="gcaagtcggtcaacaaattgatgactccgCTTGTAAAgagct cctgaagagAGTTAATATCATTCATGATCctgactaagatcgatcccgccgaccgctg a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1502105) /Source="Nicolas_upshifts" /id="U1182" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.63036963036963" /psig="0.954045954045954" /xcortree=1712 /SigmaFactorBS="gcaagtcggtcaacaaattgatgactccgCTTGTAAAgagct cctgaagagAGTTAATATCATTCATGATCctgactaagatcgatcccgccgaccgctg a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(1502129..1502136) /Source="Nicolas_upshift_promotors" /id="U1182" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.63036963036963" /psig="0.954045954045954" /xcortree=1712 /SigmaFactorBS="gcaagtcggtcaacaaattgatgactccgCTTGTAAAgagct cctgaagagAGTTAATATCATTCATGATCctgactaagatcgatcccgccgaccgctg a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1503523..1503532 /Source="Nicolas_upshift_promotors" /id="U1183" /multdbtbs="SigW" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1690 /SigmaFactorBS="atattgaaggtttttggaaatttattagaaaaacaTGAAACT TTTtgatatccttcCCGTACTATTTGTTAGatattctcaaggaggttttgaaatggaa a" /listShort="yknW, yknX, yknY, yknZ, S522, fruR" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1503544..1503559 /Source="Nicolas_upshift_promotors" /id="U1183" /multdbtbs="SigW" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1690 /SigmaFactorBS="atattgaaggtttttggaaatttattagaaaaacaTGAAACT TTTtgatatccttcCCGTACTATTTGTTAGatattctcaaggaggttttgaaatggaa a" /listShort="yknW, yknX, yknY, yknZ, S522, fruR" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1503548 /Source="Nicolas_upshifts" /id="U1183" /multdbtbs="SigW" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1690 /SigmaFactorBS="atattgaaggtttttggaaatttattagaaaaacaTGAAACT TTTtgatatccttcCCGTACTATTTGTTAGatattctcaaggaggttttgaaatggaa a" /listShort="yknW, yknX, yknY, yknZ, S522, fruR" /GFF_Attribute="listLong" CDS 1503582..1504277 /gene="skiW" /locus_tag="BSU_14340" /old_locus_tag="BSU14340" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:15849754, 16850406, 22707703" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15849754, 16850406, 22707703; Product type t: transporter" /codon_start=1 /transl_table=11 /product="subunit of permease exporting the starvation-induced killing protein" /protein_id="NP_389317.1" /db_xref="EnsemblGenomes-Gn:BSU14340" /db_xref="EnsemblGenomes-Tr:CAB13307" /db_xref="GOA:O31709" /db_xref="InterPro:IPR006977" /db_xref="SubtiList:BG13243" /db_xref="UniProtKB/Swiss-Prot:O31709" /translation="METNVEKNSGTATEKPSLFGVITSPSVQFERIRERPAVWGPLLI VAAIIIVGAVLQSLGTDYSELLKSQDTQGLSAEQMETVATITKFGGMAGAIIGGIAAL FIAPLIYWLCVKVSGGVTTYKKMLSLSLFVSLISSLGLLVNGIVAFTTDVNPLYSTTS LAGIIPSDGALASVLNTFEIFSIWSFVLLAIGLHKTGGISKKAGWISAIILFGILVVF SLFSGLINSVAGA*" gene 1503582..1504277 /gene="skiW" /locus_tag="BSU_14340" /old_locus_tag="BSU14340" CDS 1504282..1505415 /gene="skiX" /locus_tag="BSU_14350" /old_locus_tag="BSU14350" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:11544226, 22707703" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11544226, 22707703; Product type t: transporter" /codon_start=1 /transl_table=11 /product="subunit of efflux permease exporting the starvation-induced killing protein" /protein_id="NP_389318.1" /db_xref="EnsemblGenomes-Gn:BSU14350" /db_xref="EnsemblGenomes-Tr:CAB13308" /db_xref="GOA:O31710" /db_xref="InterPro:IPR006143" /db_xref="InterPro:IPR032317" /db_xref="SubtiList:BG13244" /db_xref="UniProtKB/Swiss-Prot:O31710" /translation="MKKVWIGIGIAVIVALFVGINIYRSAAPTSGSAGKEVQTGSVEE NEISSTVMVPGTLKFSNEQYVFYEADKGTLEDIKVKEGDKVKKGTALVTYTNEQLSLE KEQNQLTSESNRLQIDQIQEKLKALDSKERELEKQVGKKEAEKQIESERTELQMQKKT AEIELKQTELQRQSLANRVSDLEVKSEIEGTVISVNQEAASKKSDIQEPVIHIGNPKD LVVSGKLSEYDTLKVKKGQKVTLTSDVIQGKTWKGTVSAVGLVPDQQESAAAQGTEQA VQYPLQVKIKGNLPEGKPGFKFIMNIETDKRKANTLPSKAVKKEDDQYYVYTVKDGKA KRVDVKIGEVTDDLTEIKEGLTQDDQVILNPSDQVTDGMEVKS*" gene 1504282..1505415 /gene="skiX" /locus_tag="BSU_14350" /old_locus_tag="BSU14350" CDS 1505416..1506108 /gene="skiY" /locus_tag="BSU_14360" /old_locus_tag="BSU14360" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:9987136, 22707703" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9987136, 22707703; Product type t: transporter" /codon_start=1 /transl_table=11 /product="subunit of efflux permease exporting the starvation-induced killing protein (ATP-binding protein)" /protein_id="NP_389319.1" /db_xref="EnsemblGenomes-Gn:BSU14360" /db_xref="EnsemblGenomes-Tr:CAB13309" /db_xref="GOA:O31711" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR017871" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG13245" /db_xref="UniProtKB/Swiss-Prot:O31711" /translation="MIQLSNVRKSYQIGKETFDVLHSIDLDIHQGEYVSIMGPSGSGK STIMNIIGCLDRPTSGTYQLDGEDISSYKDKELAAVRNRSIGFVFQQFQLLPRLNAKK NVELPMIYSGIGKKERQERAERALEKVGLADRMLHMPNELSGGQKQRVAIARAIVNEP KLILADEPTGALDTKTSEAIMDQFTALNAEGTTIVLVTHEPEVADCTNRIVMVRDGNI VPASSGQRSVGE*" gene 1505416..1506108 /gene="skiY" /locus_tag="BSU_14360" /old_locus_tag="BSU14360" CDS 1506105..1507298 /gene="skiZ" /locus_tag="BSU_14370" /old_locus_tag="BSU14370" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:9987136, 22707703, 22720735, 27243566" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9987136, 22707703, 22720735, 27243566; Product type t: transporter" /codon_start=1 /transl_table=11 /product="permease subunit exporting Sporulation-Delaying Protein" /protein_id="NP_389320.1" /db_xref="EnsemblGenomes-Gn:BSU14370" /db_xref="EnsemblGenomes-Tr:CAB13310" /db_xref="GOA:O31712" /db_xref="InterPro:IPR003838" /db_xref="InterPro:IPR005085" /db_xref="InterPro:IPR025857" /db_xref="SubtiList:BG13246" /db_xref="UniProtKB/Swiss-Prot:O31712" /translation="MSLLENIRMALSSVLAHKMRSILTMLGIIIGVGSVIVVVAVGQG GEQMLKQSISGPGNTVELYYMPSDEELASNPNAAAESTFTENDIKGLKGIEGIKQVVA STSESMKARYHEEETDATVNGINDGYMNVNSLKIESGRTFTDNDFLAGNRVGIISQKM AKELFDKTSPLGEVVWINGQPVEIIGVLKKVTGLLSFDLSEMYVPFNMMKSSFGTSDF SNVSLQVESADDIKSAGKEAAQLVNDNHGTEDSYQVMNMEEIAAGIGKVTAIMTTIIG SIAGISLLVGGIGVMNIMLVSVTERTREIGIRKSLGATRGQILTQFLIESVVLTLIGG LVGIGIGYGGAALVSAIAGWPSLISWQVVCGGVLFSMLIGVIFGMLPANKAAKLDPIE ALRYE*" gene 1506105..1507298 /gene="skiZ" /locus_tag="BSU_14370" /old_locus_tag="BSU14370" downshifts 1507276 /Source="Nicolas_upshifts" /id="D800" /incds=0 /nref=79 /ntot=210 /MaxReadThrough="3.49546" /MaxDrop="4.46952" /score="36.2703425" /energy="-12.1" /TU="U1183" /idTUdmin="U1183" /TUdmin="-396" /isTUend="FALSE" promotor_-35 1507347..1507353 /Source="Nicolas_upshift_promotors" /id="U1184" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.86013986013986" /psig="0.86013986013986" /xcortree=1212 /SigmaFactorBS="tgaggtttttttatgtttagtgatttctactaTGAATATaaa agacttttttCATTAAAATAAGaagaaaatgtcgtacaattgtccttatttttgtcga a" /listShort="S522, fruR" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1507367..1507378 /Source="Nicolas_upshift_promotors" /id="U1184" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.86013986013986" /psig="0.86013986013986" /xcortree=1212 /SigmaFactorBS="tgaggtttttttatgtttagtgatttctactaTGAATATaaa agacttttttCATTAAAATAAGaagaaaatgtcgtacaattgtccttatttttgtcga a" /listShort="S522, fruR" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1507375 /Source="Nicolas_upshifts" /id="U1184" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.86013986013986" /psig="0.86013986013986" /xcortree=1212 /SigmaFactorBS="tgaggtttttttatgtttagtgatttctactaTGAATATaaa agacttttttCATTAAAATAAGaagaaaatgtcgtacaattgtccttatttttgtcga a" /listShort="S522, fruR" /GFF_Attribute="listLong" promotor_-35 1507420..1507427 /Source="Nicolas_upshift_promotors" /id="U1185" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.87012987012987" /psig="0.967032967032967" /xcortree=1 /SigmaFactorBS="gtcgtacaattgtccttatttttgtcgaatttaCAGTTTACa aaccctatagacaTACGTTAATATGGAGAAACGtgaaagattttgatagttattgaat g" /listShort="S522, fruR, fruK, fruA" /listLong="sipT" /label="promotor_-35" promotor_-10 1507442..1507461 /Source="Nicolas_upshift_promotors" /id="U1185" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.87012987012987" /psig="0.967032967032967" /xcortree=1 /SigmaFactorBS="gtcgtacaattgtccttatttttgtcgaatttaCAGTTTACa aaccctatagacaTACGTTAATATGGAGAAACGtgaaagattttgatagttattgaat g" /listShort="S522, fruR, fruK, fruA" /listLong="sipT" /label="promotor_-10" S_feature 1507447..1507538 /Source="Nicolas_S_feature" /locus_tag="new_1507447_1507538" /HighExp="UNK1, LPh, HPh, Fru, G180, MG 5, C30, G135, MG t5, MG 10" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigGF, SigWXY" /TUshortPSig="0.967, 0.86, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S522" upshifts 1507447 /Source="Nicolas_upshifts" /id="U1185" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.87012987012987" /psig="0.967032967032967" /xcortree=1 /SigmaFactorBS="gtcgtacaattgtccttatttttgtcgaatttaCAGTTTACa aaccctatagacaTACGTTAATATGGAGAAACGtgaaagattttgatagttattgaat g" /listShort="S522, fruR, fruK, fruA" /listLong="sipT" promotor_-35 1507502..1507509 /Source="Nicolas_upshift_promotors" /id="U1186" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.814185814185814" /psig="0.999000999001" /xcortree=2 /SigmaFactorBS="attgaatgaatttgaatgatttTAGTTGCCtaaaccgaaaat aGCGTTTACAATGAAATTGTAttcaaaatgaatacgttttcattaggaggtgaagcat g" /listShort="fruR, fruK, fruA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1507523..1507542 /Source="Nicolas_upshift_promotors" /id="U1186" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.814185814185814" /psig="0.999000999001" /xcortree=2 /SigmaFactorBS="attgaatgaatttgaatgatttTAGTTGCCtaaaccgaaaat aGCGTTTACAATGAAATTGTAttcaaaatgaatacgttttcattaggaggtgaagcat g" /listShort="fruR, fruK, fruA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1507540 /Source="Nicolas_upshifts" /id="U1186" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.814185814185814" /psig="0.999000999001" /xcortree=2 /SigmaFactorBS="attgaatgaatttgaatgatttTAGTTGCCtaaaccgaaaat aGCGTTTACAATGAAATTGTAttcaaaatgaatacgttttcattaggaggtgaagcat g" /listShort="fruR, fruK, fruA" /GFF_Attribute="listLong" CDS 1507578..1508333 /gene="fruR" /locus_tag="BSU_14380" /old_locus_tag="BSU14380" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 14563858; Product type r : regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator (DeoR family)" /protein_id="NP_389321.1" /db_xref="EnsemblGenomes-Gn:BSU14380" /db_xref="EnsemblGenomes-Tr:CAB13311" /db_xref="GOA:O31713" /db_xref="InterPro:IPR001034" /db_xref="InterPro:IPR014036" /db_xref="InterPro:IPR018356" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG12589" /db_xref="UniProtKB/Swiss-Prot:O31713" /translation="MLTPERHQLIIDQIEKHDVVKIQELINLTNASESTIRRDLSTLE ERGFLKRVHGGAAKLSDIRLEPDMLEKSSKNLHDKLKIAEKAASLLEEGDCIYLDAGT TTLHMIDFMDKTKDIVVVTNGVMHIDALIRKEISFYLLGGYVKHRTGAIIGGASLVAM DQYRFDKSFLGTNGVHTEAGFTTPDPDEALLKQKAIKQAKHAYVLADPSKFGEISFSA FAGIGDATIITTDAEELTFDNYQEKTVVKVVKP*" gene 1507578..1508333 /gene="fruR" /locus_tag="BSU_14380" /old_locus_tag="BSU14380" upshifts complement(1507726) /Source="Nicolas_upshifts" /id="U1187" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.74925074925075" /psig="0.015984015984016" /xcortree=3 /SigmaFactorBS="tcaagcatatcgggttcaagtctgatatcggaaagcttGgcc gctccaccatgaacGCGctttaaaaaaccgcgttcttcaagggtcgataaatctcttc t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 complement(1507728..1507730) /Source="Nicolas_upshift_promotors" /id="U1187" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.74925074925075" /psig="0.015984015984016" /xcortree=3 /SigmaFactorBS="tcaagcatatcgggttcaagtctgatatcggaaagcttGgcc gctccaccatgaacGCGctttaaaaaaccgcgttcttcaagggtcgataaatctcttc t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 complement(1507748) /Source="Nicolas_upshift_promotors" /id="U1187" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.74925074925075" /psig="0.015984015984016" /xcortree=3 /SigmaFactorBS="tcaagcatatcgggttcaagtctgatatcggaaagcttGgcc gctccaccatgaacGCGctttaaaaaaccgcgttcttcaagggtcgataaatctcttc t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" CDS 1508330..1509241 /gene="fruK" /locus_tag="BSU_14390" /old_locus_tag="BSU14390" /EC_number="2.7.1.56" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1c: Function from experimental evidences in the studied genus; PubMedId: 168069, 14563858, 24328040; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="fructose-1-phosphate kinase" /protein_id="NP_389322.1" /db_xref="EnsemblGenomes-Gn:BSU14390" /db_xref="EnsemblGenomes-Tr:CAB13312" /db_xref="GOA:O31714" /db_xref="InterPro:IPR002173" /db_xref="InterPro:IPR011611" /db_xref="InterPro:IPR017583" /db_xref="InterPro:IPR022463" /db_xref="InterPro:IPR023314" /db_xref="InterPro:IPR029056" /db_xref="SubtiList:BG12588" /db_xref="UniProtKB/Swiss-Prot:O31714" /translation="MIYTVTLNPSVDYIVHVEDFTVGGLNRSSYDTKYPGGKGINVSR LLKRHHVASKALGFVGGFTGEYIKTFLREENLETAFSEVKGDTRINVKLKTGDETEIN GQGPTISDEDFKAFLEQFQSLQEGDIVVLAGSIPSSLPHDTYEKIAEACKQQNARVVL DISGEALLKATEMKPFLMKPNHHELGEMFGTAITSVEEAVPYGKKLVEQGAEHVIVSM AGDGALLFTNEAVYFANVPKGKLVNSVGAGDSVVAGFLAGISKQLPLEEAFRLGVTSG SATAFSEELGTEEFVQQLLPEVKVTRL*" gene 1508330..1509241 /gene="fruK" /locus_tag="BSU_14390" /old_locus_tag="BSU14390" CDS 1509256..1511163 /gene="fruA" /locus_tag="BSU_14400" /old_locus_tag="BSU14400" /EC_number="2.7.1.202" /function="16.11: Scavenge (Catabolism)" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:118007, 200418" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 118007, 200418; Product type t: transporter" /codon_start=1 /transl_table=11 /product="phosphotransferase system (PTS) fructose-specific enzyme IIABC component" /protein_id="NP_389323.1" /db_xref="EnsemblGenomes-Gn:BSU14400" /db_xref="EnsemblGenomes-Tr:CAB13313" /db_xref="GOA:P71012" /db_xref="InterPro:IPR002178" /db_xref="InterPro:IPR003353" /db_xref="InterPro:IPR003501" /db_xref="InterPro:IPR004715" /db_xref="InterPro:IPR006327" /db_xref="InterPro:IPR013011" /db_xref="InterPro:IPR013014" /db_xref="InterPro:IPR016152" /db_xref="InterPro:IPR036095" /db_xref="PDB:2R4Q" /db_xref="SubtiList:BG11938" /db_xref="UniProtKB/Swiss-Prot:P71012" /translation="MKITELLTKHTIKLNIESKEKENVIDEMVTVLDKAGKLNDRQAY KEAILNRESQSSTGIGEGIAIPHAKTASVINPAIAFGRSKDGVDYESLDGQPAHLVFM IAATEGANNTHLEALSRLSTLLMREEIRKQLLEAESEDAIIDIINQHDKDDDEEEEEE EAAPAPAGKGKILAVTACPTGIAHTFMAADALKEKAKELGVEIKVETNGSSGIKHKLT AQEIEDAPAIIVAADKQVEMERFKGKRVLQVPVTAGIRRPQELIEKAMNQDAPIYQGS GGGSAASNDDEEAKGKSGSGIGNTFYKHLMSGVSNMLPFVVGGGILVAISFFWGIHSA DPNDPSYNTFAAALNFIGGDNALKLIVAVLAGFIAMSIADRPGFAPGMVGGFMATQAN AGFLGGLIAGFLAGYVVILLKKVFTFIPQSLDGLKPVLIYPLFGIFITGVLMQFVVNT PVAAFMNFLTNWLESLGTGNLVLMGIILGGMMAIDMGGPLNKAAFTFGIAMIDAGNYA PHAAIMAGGMVPPLGIALATTIFRNKFTQRDREAGITCYFMGAAFVTEGAIPFAAADP LRVIPAAVVGAAVAGGLTEFFRVTLPAPHGGVFVAFITNHPMLYLLSIVIGAVVMAII LGIVKKPVTEK*" gene 1509256..1511163 /gene="fruA" /locus_tag="BSU_14400" /old_locus_tag="BSU14400" downshifts 1511148 /Source="Nicolas_upshifts" /id="D801" /incds=0 /nref=133 /ntot=228 /MaxReadThrough="3.99928" /MaxDrop="5.27169" /score="11.7516734" /energy="-11.4" /TU="U1185" /idTUdmin="U1186" /TUdmin=0 /isTUend="TRUE" promotor_-35 1511232..1511239 /Source="Nicolas_upshift_promotors" /id="U1188" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.984015984015984" /psig=1 /xcortree=1910 /SigmaFactorBS="gctttttcttatccggccggcagggagcgcggttaagttATG TATTTtattctttttTATGATAAAGTAAAAGAAGAgaaacaactgacatagcaattgt c" /listShort="sipT" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1511250..1511269 /Source="Nicolas_upshift_promotors" /id="U1188" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.984015984015984" /psig=1 /xcortree=1910 /SigmaFactorBS="gctttttcttatccggccggcagggagcgcggttaagttATG TATTTtattctttttTATGATAAAGTAAAAGAAGAgaaacaactgacatagcaattgt c" /listShort="sipT" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1511253 /Source="Nicolas_upshifts" /id="U1188" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.984015984015984" /psig=1 /xcortree=1910 /SigmaFactorBS="gctttttcttatccggccggcagggagcgcggttaagttATG TATTTtattctttttTATGATAAAGTAAAAGAAGAgaaacaactgacatagcaattgt c" /listShort="sipT" /GFF_Attribute="listLong" CDS 1511308..1511889 /gene="sipT" /locus_tag="BSU_14410" /old_locus_tag="BSU14410" /EC_number="3.4.21.89" /function="16.1: Circulate" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:9325333, 10198007, 11283286, 11807061, 12897006, 27159567" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9325333, 10198007, 11283286, 11807061, 12897006, 27159567; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="type I signal peptidase" /protein_id="NP_389324.1" /db_xref="EnsemblGenomes-Gn:BSU14410" /db_xref="EnsemblGenomes-Tr:CAB13314" /db_xref="GOA:P71013" /db_xref="InterPro:IPR000223" /db_xref="InterPro:IPR015927" /db_xref="InterPro:IPR019756" /db_xref="InterPro:IPR019757" /db_xref="InterPro:IPR019758" /db_xref="InterPro:IPR036286" /db_xref="SubtiList:BG11977" /db_xref="UniProtKB/Swiss-Prot:P71013" /translation="MTEEKNTNTEKTAKKKTNTYLEWGKAIVIAVLLALLIRHFLFEP YLVEGSSMYPTLHDGERLFVNKTVNYIGELKRGDIVIINGETSKIHYVKRLIGKPGET VQMKDDTLYINGKKVAEPYLSKNKKEAEKLGVSLTGDFGPVKVPKGKYFVMGDNRLNS MDSRNGLGLIAEDRIVGTSKFVFFPFNEMRQTK*" gene 1511308..1511889 /gene="sipT" /locus_tag="BSU_14410" /old_locus_tag="BSU14410" downshifts 1511874 /Source="Nicolas_upshifts" /id="D802" /incds=0 /nref=90 /ntot=226 /MaxReadThrough="3.7981" /MaxDrop="6.13957" /score="5.03270493" /energy="-9.8" /TU="U1188" /idTUdmin="U1188" /TUdmin="-44" /isTUend="FALSE" downshifts 1511918 /Source="Nicolas_upshifts" /id="D803" /incds=0 /nref=1 /ntot=29 /MaxReadThrough="2.6676" /MaxDrop="3.60225" /score="5.03270493" /energy="-9.8" /TU="NA" /idTUdmin="U1188" /TUdmin=0 /isTUend="TRUE" CDS complement(1511923..1512192) /gene="ykoA" /locus_tag="BSU_14420" /old_locus_tag="BSU14420" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative membrane protein of unknown function" /protein_id="NP_389325.1" /db_xref="EnsemblGenomes-Gn:BSU14420" /db_xref="EnsemblGenomes-Tr:CAB13315" /db_xref="GOA:O31715" /db_xref="SubtiList:BG13247" /db_xref="UniProtKB/Swiss-Prot:O31715" /translation="MRLLTLTEYCLLIFFTGFYLAVTGFTAKDIGLYIGIALIYIFSH IFSKRLLEKRGKENKQVHLFFSVLAIIGSVFITVLCIALVASFSK*" gene complement(1511923..1512192) /gene="ykoA" /locus_tag="BSU_14420" /old_locus_tag="BSU14420" downshifts complement(1511928) /Source="Nicolas_upshifts" /id="D804" /incds=0 /nref=38 /ntot=254 /MaxReadThrough="2.08491" /MaxDrop="5.70938" /score="11.210199" /energy="-9.8" /TU="U1189" /idTUdmin="U1189" /TUdmin="-44" /isTUend="FALSE" S_feature complement(1512193..1512258) /Source="Nicolas_S_feature" /locus_tag="new_1512193_1512258_c" /HighExp="LoTm, Gly, Lbstat, Sw, Cold, C30, HPh, S0, T0.30H, Lbtran" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S523" misc_feature complement(1512239..1512258) /Source="Nicolas_upshift_promotors" /id="U1189" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.85914085914086" /psig="0.999000999001" /xcortree=2176 /SigmaFactorBS="aagagaaatgattccctgataaaacagagagaaaacacttat acacccaaaccagccagcTGTGTTACAATTAAAGAGAGagaatgcatccgcctggaaa a" /listShort="S523, ykoA" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(1512258) /Source="Nicolas_upshifts" /id="U1189" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.85914085914086" /psig="0.999000999001" /xcortree=2176 /SigmaFactorBS="aagagaaatgattccctgataaaacagagagaaaacacttat acacccaaaccagccagcTGTGTTACAATTAAAGAGAGagaatgcatccgcctggaaa a" /listShort="S523, ykoA" /GFF_Attribute="listLong" promotor_-35 1512311..1512318 /Source="Nicolas_upshift_promotors" /id="U1190" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.977022977022977" /psig=1 /xcortree=2141 /SigmaFactorBS="gtgtataagtgttttctctctgttttatcagggaatcaTTTC TCTTgccctgcattCATGGTATACTTTTATTGATgatagacatgatggaggataataa a" /listShort="ykpA, panE" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1512329..1512348 /Source="Nicolas_upshift_promotors" /id="U1190" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.977022977022977" /psig=1 /xcortree=2141 /SigmaFactorBS="gtgtataagtgttttctctctgttttatcagggaatcaTTTC TCTTgccctgcattCATGGTATACTTTTATTGATgatagacatgatggaggataataa a" /listShort="ykpA, panE" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1512333 /Source="Nicolas_upshifts" /id="U1190" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.977022977022977" /psig=1 /xcortree=2141 /SigmaFactorBS="gtgtataagtgttttctctctgttttatcagggaatcaTTTC TCTTgccctgcattCATGGTATACTTTTATTGATgatagacatgatggaggataataa a" /listShort="ykpA, panE" /GFF_Attribute="listLong" CDS 1512373..1513995 /gene="ykpA" /locus_tag="BSU_14430" /old_locus_tag="BSU14430" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 10816464, 24389466; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative energy-sensing inhibitor of translation" /protein_id="NP_389326.1" /db_xref="EnsemblGenomes-Gn:BSU14430" /db_xref="EnsemblGenomes-Tr:CAB13316" /db_xref="GOA:O31716" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR032781" /db_xref="SubtiList:BG13270" /db_xref="UniProtKB/Swiss-Prot:O31716" /translation="MIAVNNVSLRFADRKLFEDVNIKFTPGNCYGLIGANGAGKSTFL KVLSGEIEPQTGDVHMSPGERLAVLKQNHFEYEEYEVLKVVIMGHKRLYEVMQEKDAI YMKPDFSDEDGIRAAELEGEFAELNGWEAESEAAILLKGLGISEDLHTKKMADLGGSE KVKVLLAQALFGKPDVLLLDEPTNHLDLQAIQWLEEFLINFENTVIVVSHDRHFLNKV CTHIADLDFNKIQIYVGNYDFWYESSQLALKLSQEANKKKEEQIKQLQEFVARFSANA SKSKQATSRKKLLEKITLDDIKPSSRRYPYVNFTPEREIGNDVLRVEGLTKTIDGVKV LDNVSFIMNREDKIAFTGRNELAVTTLFKIISGEMEADSGTFKWGVTTSQAYFPKDNS EYFEGSDLNLVDWLRQYSPHDQSESFLRGFLGRMLFSGEEVHKKANVLSGGEKVRCML SKAMLSGANILILDEPTNHLDLESITALNNGLISFKGAMLFTSHDHQFVQTIANRIIE ITPNGIVDKQMSYDEFLENADVQKKLTELYAE*" gene 1512373..1513995 /gene="ykpA" /locus_tag="BSU_14430" /old_locus_tag="BSU14430" downshifts 1513983 /Source="Nicolas_upshifts" /id="D805" /incds=0 /nref=45 /ntot=239 /MaxReadThrough="5.13671" /MaxDrop="3.6227" /score="17.6386925" /energy="-7.6" /TU="U1190" /idTUdmin="U1190" /TUdmin="-993" /isTUend="FALSE" CDS 1514052..1514963 /gene="panE" /locus_tag="BSU_14440" /old_locus_tag="BSU14440" /EC_number="1.1.1.169" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 1844812, 15966718, 17229734; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="2-dehydropantoate reductase" /protein_id="NP_389327.1" /db_xref="EnsemblGenomes-Gn:BSU14440" /db_xref="EnsemblGenomes-Tr:CAB13317" /db_xref="GOA:O31717" /db_xref="InterPro:IPR003710" /db_xref="InterPro:IPR008927" /db_xref="InterPro:IPR013328" /db_xref="InterPro:IPR013332" /db_xref="InterPro:IPR013752" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG13271" /db_xref="UniProtKB/Swiss-Prot:O31717" /translation="MKFLVVGAGGVGGYIGGRLSEKGNDVTFLVRQKRAEQLKKTGLV IHSEKGNVSFQPELISAGETGQFDVVIIASKAYSLGQVIEDVKPFIHQESVIIPFLNG YRHYEQLFAAFSKEQVLGGLCFIESALDNKGEIHHTSASHRFVFGEWNGERTERIRAL EEAFSGVKAEVIISGHIEKDIWKKYLFIAAQAGITTLFQRPLGPILATEAGRHTAQTL IGEICTVLRKEGVPADPALEEESFRTMTSMSYHMKSSMLRDMENGQTTEGDHLHGFLI EKAKRLSLAAPVLETVYANLQMYEAEK*" gene 1514052..1514963 /gene="panE" /locus_tag="BSU_14440" /old_locus_tag="BSU14440" downshifts 1514968 /Source="Nicolas_upshifts" /id="D806" /incds=0 /nref=120 /ntot=228 /MaxReadThrough="2.04919" /MaxDrop="4.55439" /score="11.4959806" /energy="-9.6" /TU="NA" /idTUdmin="U1190" /TUdmin="-8" /isTUend="TRUE" CDS complement(1514997..1516229) /gene="ampS" /locus_tag="BSU_14450" /old_locus_tag="BSU14450" /EC_number="3.4.11.24" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:9362117, 16088219, 22808738" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9362117, 16088219, 22808738; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="aminopeptidase" /protein_id="NP_389328.1" /db_xref="EnsemblGenomes-Gn:BSU14450" /db_xref="EnsemblGenomes-Tr:CAB13318" /db_xref="GOA:P39762" /db_xref="InterPro:IPR000787" /db_xref="InterPro:IPR035097" /db_xref="SubtiList:BG10986" /db_xref="UniProtKB/Swiss-Prot:P39762" /translation="MDSFSQKLNTYAQLAVEVGVNVQKGQYVVVNASTDVRDFVRLIV KHAYEKGAKNVTVNWQDDEVAKLKYELAPFEAFEEYPEWEAKGREELAKNGAAFISVV SSNPDLLKGIDSKRIAAFQKAAGKALHTYRQYIQSDKVSWTVVGAASAGWAHKVFPGK SEEEAIHLLWEEIFKATRVNEDNPVQAWINHDQNLHEKVDHLNERHYAALHYQAEGTD LTIKLPRKHVWAGAGSVNESGHEFMANMPTEEVFTLPQKDGVDGVVSSTKPLSYGGNI IENFTLTFENGRIVDIKAEKGEDILKELVETDEGSHYLGEVALVPYDSPISQSNILFY NTLFDENASNHLAIGSAYAFNIEGGKQMSREELVKEGLNESITHVDFMIGSKDMNIDG ITADGKREPIFRNGNWAF*" gene complement(1514997..1516229) /gene="ampS" /locus_tag="BSU_14450" /old_locus_tag="BSU14450" downshifts complement(1515008) /Source="Nicolas_upshifts" /id="D807" /incds=0 /nref=215 /ntot=254 /MaxReadThrough="1.34101" /MaxDrop="5.7635" /score="40.7811053" /energy="-9.6" /TU="NA" /idTUdmin="U1191" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(1516247..1516266) /Source="Nicolas_upshift_promotors" /id="U1191" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.454545454545455" /psig="0.982017982017982" /xcortree=2338 /SigmaFactorBS="aaaacccaagacgtgtcgttttgggtttttcactttgggctc cttCTTTCCtttataggatcataTTTGATATGATGAGAAAAAAgcttggaggaatgat t" /listShort="ampS" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1516271) /Source="Nicolas_upshifts" /id="U1191" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.454545454545455" /psig="0.982017982017982" /xcortree=2338 /SigmaFactorBS="aaaacccaagacgtgtcgttttgggtttttcactttgggctc cttCTTTCCtttataggatcataTTTGATATGATGAGAAAAAAgcttggaggaatgat t" /listShort="ampS" /GFF_Attribute="listLong" promotor_-35 complement(1516281..1516286) /Source="Nicolas_upshift_promotors" /id="U1191" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.454545454545455" /psig="0.982017982017982" /xcortree=2338 /SigmaFactorBS="aaaacccaagacgtgtcgttttgggtttttcactttgggctc cttCTTTCCtttataggatcataTTTGATATGATGAGAAAAAAgcttggaggaatgat t" /listShort="ampS" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(1516339..1516473) /gene="ykpC" /locus_tag="BSU_14460" /old_locus_tag="BSU14460" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_389329.1" /db_xref="EnsemblGenomes-Gn:BSU14460" /db_xref="EnsemblGenomes-Tr:CAB13319" /db_xref="InterPro:IPR035379" /db_xref="SubtiList:BG11812" /db_xref="UniProtKB/Swiss-Prot:Q45492" /translation="MLRDLGRRVAIAAILSGIILGGMSISLANMPHSPAGGTVKLNHP *" gene complement(1516339..1516473) /gene="ykpC" /locus_tag="BSU_14460" /old_locus_tag="BSU14460" downshifts complement(1516350) /Source="Nicolas_upshifts" /id="D808" /incds=0 /nref=51 /ntot=151 /MaxReadThrough="3.10365" /MaxDrop="5.04142" /score="-2.2377884" /energy="-9.1" /TU="U1192" /idTUdmin="U1193" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(1516495..1516513) /Source="Nicolas_upshift_promotors" /id="U1192" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.863136863136863" /psig="0.863136863136863" /xcortree=1021 /SigmaFactorBS="ccgcaaaattctcacacgcggcaaatttcttgCTTCTTtttt cctcacttcctTCATATTGTGGGAAATGGAgaaacgttaaggaggaaacagatgctaa g" /listShort="ykpC, ampS" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1516506) /Source="Nicolas_upshifts" /id="U1192" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.863136863136863" /psig="0.863136863136863" /xcortree=1021 /SigmaFactorBS="ccgcaaaattctcacacgcggcaaatttcttgCTTCTTtttt cctcacttcctTCATATTGTGGGAAATGGAgaaacgttaaggaggaaacagatgctaa g" /listShort="ykpC, ampS" /GFF_Attribute="listLong" S_feature complement(1516508..1516573) /Source="Nicolas_S_feature" /locus_tag="new_1516508_1516573_c" /HighExp="HiTm, C30, Lbstat, MG-0.2, BC, G135, MG 15, MG 10, MG-0.1, MG 5" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigI" /TUshortPSig="0.982" /TUlongSig="NA" /TUlongPSig="NA" /label="S524" promotor_-35 complement(1516529..1516534) /Source="Nicolas_upshift_promotors" /id="U1192" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.863136863136863" /psig="0.863136863136863" /xcortree=1021 /SigmaFactorBS="ccgcaaaattctcacacgcggcaaatttcttgCTTCTTtttt cctcacttcctTCATATTGTGGGAAATGGAgaaacgttaaggaggaaacagatgctaa g" /listShort="ykpC, ampS" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(1516574..1517581) /gene="mreBH" /locus_tag="BSU_14470" /old_locus_tag="BSU14470" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:16950129, 19643765, 19659933, 21091501, 21636651, 26091431" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16950129, 19643765, 19659933, 21091501, 21636651, 26091431; Product type f : factor" /codon_start=1 /transl_table=11 /product="cell-shape determining protein" /protein_id="NP_389330.1" /db_xref="EnsemblGenomes-Gn:BSU14470" /db_xref="EnsemblGenomes-Tr:CAB13320" /db_xref="GOA:P39763" /db_xref="InterPro:IPR004753" /db_xref="SubtiList:BG10987" /db_xref="UniProtKB/Swiss-Prot:P39763" /translation="MFQSTEIGIDLGTANILVYSKNKGIILNEPSVVAVDTTTKAVLA IGADAKNMIGKTPGKIVAVRPMKDGVIADYDMTTDLLKHIMKKAAKSIGMSFRKPNVV VCTPSGSTAVERRAISDAVKNCGAKNVHLIEEPVAAAIGADLPVDEPVANVVVDIGGG TTEVAIISFGGVVSCHSIRIGGDQLDEDIVSFVRKKYNLLIGERTAEQVKMEIGHALI EHIPEAMEIRGRDLVTGLPKTIMLQSNEIQDAMRESLLHILEAIRATLEDCPPELSGD IVDRGVILTGGGALLNGIKEWLTEEIVVPVHVAQNPLESVAIGTGRSLEVIDKLQKAI K*" gene complement(1516574..1517581) /gene="mreBH" /locus_tag="BSU_14470" /old_locus_tag="BSU14470" upshifts complement(1517627) /Source="Nicolas_upshifts" /id="U1193" /multdbtbs="-" /comp="M2" /sig="SigI" /pcomp="0.982017982017982" /psig="0.982017982017982" /xcortree=1772 /SigmaFactorBS="ttacaaaaacatttctttaccgacgcacaCCCCCAAAAatcg cagtatttcTGAGAAACTttaaatgtagaatcatattaaattaggatagagattgggt g" /listShort="mreBH, S524, ykpC" /GFF_Attribute="listLong" promotor_-10 complement(1517628..1517636) /Source="Nicolas_upshift_promotors" /id="U1193" /multdbtbs="-" /comp="M2" /sig="SigI" /pcomp="0.982017982017982" /psig="0.982017982017982" /xcortree=1772 /SigmaFactorBS="ttacaaaaacatttctttaccgacgcacaCCCCCAAAAatcg cagtatttcTGAGAAACTttaaatgtagaatcatattaaattaggatagagattgggt g" /listShort="mreBH, S524, ykpC" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 complement(1517650..1517658) /Source="Nicolas_upshift_promotors" /id="U1193" /multdbtbs="-" /comp="M2" /sig="SigI" /pcomp="0.982017982017982" /psig="0.982017982017982" /xcortree=1772 /SigmaFactorBS="ttacaaaaacatttctttaccgacgcacaCCCCCAAAAatcg cagtatttcTGAGAAACTttaaatgtagaatcatattaaattaggatagagattgggt g" /listShort="mreBH, S524, ykpC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1517768..1517777 /Source="Nicolas_upshift_promotors" /id="U1194" /multdbtbs="SigW,SigX" /comp="M9" /sig="SigWXY" /pcomp="0.88011988011988" /psig="0.88011988011988" /xcortree=1803 /SigmaFactorBS="ttttatggaaaaaatatcttgtaattcttatagaaagcgGGA AACTTTTtcaaagtttcatTCGTCTACGATATATTgaggtacatccttaaaacattac a" /listShort="S525, abh, S527" /listLong="kinC, ykqA, ktrC" /label="promotor_-35" upshifts 1517789 /Source="Nicolas_upshifts" /id="U1194" /multdbtbs="SigW,SigX" /comp="M9" /sig="SigWXY" /pcomp="0.88011988011988" /psig="0.88011988011988" /xcortree=1803 /SigmaFactorBS="ttttatggaaaaaatatcttgtaattcttatagaaagcgGGA AACTTTTtcaaagtttcatTCGTCTACGATATATTgaggtacatccttaaaacattac a" /listShort="S525, abh, S527" /listLong="kinC, ykqA, ktrC" promotor_-10 1517790..1517805 /Source="Nicolas_upshift_promotors" /id="U1194" /multdbtbs="SigW,SigX" /comp="M9" /sig="SigWXY" /pcomp="0.88011988011988" /psig="0.88011988011988" /xcortree=1803 /SigmaFactorBS="ttttatggaaaaaatatcttgtaattcttatagaaagcgGGA AACTTTTtcaaagtttcatTCGTCTACGATATATTgaggtacatccttaaaacattac a" /listShort="S525, abh, S527" /listLong="kinC, ykqA, ktrC" /label="promotor_-10" S_feature 1517792..1517864 /Source="Nicolas_S_feature" /locus_tag="new_1517792_1517864" /HighExp="Lbexp, dia5, LBGexp, dia0, Lbtran, Mt0, Oxctl, Paraq, M0t45, G180" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigWXY" /TUshortPSig="0.88" /TUlongSig="NA" /TUlongPSig="NA" /label="S525" CDS 1517865..1518143 /gene="abhA" /locus_tag="BSU_14480" /old_locus_tag="BSU14480" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:16159768, 17720793, 19767430, 20817675, 20844865" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16159768, 17720793, 19767430, 20817675, 20844865; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator" /protein_id="NP_389331.1" /db_xref="EnsemblGenomes-Gn:BSU14480" /db_xref="EnsemblGenomes-Tr:CAB13321" /db_xref="GOA:P39758" /db_xref="InterPro:IPR007159" /db_xref="PDB:2FY9" /db_xref="PDB:2RO3" /db_xref="SubtiList:BG10988" /db_xref="UniProtKB/Swiss-Prot:P39758" /translation="MKSIGVVRKVDELGRIVMPIELRRALDIAIKDSIEFFVDGDKII LKKYKPHGVCLMTGEITSENKEYGNGKITLSPEGAQLLLEEIQAALKE*" gene 1517865..1518143 /gene="abhA" /locus_tag="BSU_14480" /old_locus_tag="BSU14480" downshifts 1518141 /Source="Nicolas_upshifts" /id="D809" /incds=0 /nref=61 /ntot=238 /MaxReadThrough="4.68201" /MaxDrop="5.62457" /score="7.91393519" /energy="-11" /TU="U1194" /idTUdmin="U1194" /TUdmin="-135" /isTUend="FALSE" S_feature complement(1518175..1519804) /Source="Nicolas_S_feature" /locus_tag="new_1518175_1519804_c" /HighExp="S6, S8, S5, LoTm, S4, S7, S3, C30, T5.0H, BT" /AntisenseName="kinC" /AntisenseCor="-0.76370141168998495" /AntisenseRegPval="-51.9" /CDS_PredictionProba="NA" /TUshortSig="SigEF" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S526" S_feature 1518186..1518290 /Source="Nicolas_S_feature" /locus_tag="new_1518186_1518290" /HighExp="Oxctl, Lbexp, LBGexp, H2O2, dia0, Paraq, G180, G150, G135, LBGtran" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigWXY" /TUshortPSig="0.88" /TUlongSig="NA" /TUlongPSig="NA" /label="S527" downshifts complement(1518198) /Source="Nicolas_upshifts" /id="D810" /incds=0 /nref=1 /ntot=22 /MaxReadThrough="0.833919999999999" /MaxDrop="3.11258" /score="8.02057524" /energy="-11" /TU="NA" /idTUdmin="U1196" /TUdmin=0 /isTUend="TRUE" promotor_-35 1518272..1518279 /Source="Nicolas_upshift_promotors" /id="U1195" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.986013986013986" /psig=1 /xcortree=2153 /SigmaFactorBS="atatttggtaatgaatgatttgggatactttacatattttAC TCAATTatttgtcgaagAATGGTACAATAAGTAGAGAaacacaagcggcaggtggtca t" /listShort="kinC, ykqA, ktrC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1518291..1518310 /Source="Nicolas_upshift_promotors" /id="U1195" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.986013986013986" /psig=1 /xcortree=2153 /SigmaFactorBS="atatttggtaatgaatgatttgggatactttacatattttAC TCAATTatttgtcgaagAATGGTACAATAAGTAGAGAaacacaagcggcaggtggtca t" /listShort="kinC, ykqA, ktrC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1518292 /Source="Nicolas_upshifts" /id="U1195" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.986013986013986" /psig=1 /xcortree=2153 /SigmaFactorBS="atatttggtaatgaatgatttgggatactttacatattttAC TCAATTatttgtcgaagAATGGTACAATAAGTAGAGAaacacaagcggcaggtggtca t" /listShort="kinC, ykqA, ktrC" /GFF_Attribute="listLong" CDS 1518333..1519619 /gene="kinC" /locus_tag="BSU_14490" /old_locus_tag="BSU14490" /EC_number="2.7.13.3" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:11069677, 11673427, 7836330, 20971918, 25701730, 26152584, 23569226, 26297017" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11069677, 11673427, 7836330, 20971918, 25701730, 26152584, 23569226, 26297017; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="two-component sensor potassium-responsive histidine kinase regulating cannibalism and biofilm formation" /protein_id="NP_389332.1" /db_xref="EnsemblGenomes-Gn:BSU14490" /db_xref="EnsemblGenomes-Tr:CAB13322" /db_xref="GOA:P39764" /db_xref="InterPro:IPR000014" /db_xref="InterPro:IPR000700" /db_xref="InterPro:IPR001610" /db_xref="InterPro:IPR003594" /db_xref="InterPro:IPR003661" /db_xref="InterPro:IPR004358" /db_xref="InterPro:IPR005467" /db_xref="InterPro:IPR013767" /db_xref="InterPro:IPR035965" /db_xref="InterPro:IPR036097" /db_xref="InterPro:IPR036890" /db_xref="SubtiList:BG10989" /db_xref="UniProtKB/Swiss-Prot:P39764" /translation="MRKYQARIISIILAMIFIMFWDYLFYFIGKNPINWPVDIVYTAV TLVSVWMLAYYIDEKQQLVKKMKDNEWKYKQLSEEKNRIMDNLQEIVFQTNAKGEITY LNQAWASITGFSISECMGTMYNDYFIKEKHVADHINTQIQNKASSGMFTAKYVTKNGT IFWGEVHYKLYYDRDDQFTGSLGTMSDITERKEAEDELIEINERLARESQKLSITSEL AAGIAHEVRNPLTSVSGFLQIMKTQYPDRKDYFDIIFSEIKRIDLVLSELLLLAKPQA ITFKTHQLNEILKQVTTLLDTNAILSNIVIEKNFKETDGCMINGDENQLKQVFINIIK NGIEAMPKGGVVTISTAKTASHAVISVKDEGNGMPQEKLKQIGKPFYSTKEKGTGLGL PICLRILKEHDGELKIESEAGKGSVFQVVLPLKSDS*" gene 1518333..1519619 /gene="kinC" /locus_tag="BSU_14490" /old_locus_tag="BSU14490" CDS 1519635..1520468 /gene="ykqA" /locus_tag="BSU_14500" /old_locus_tag="BSU14500" /EC_number="2.3.2.-" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 28537416; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative gamma-glutamylcyclotransferase (bacillithiol degradation)" /protein_id="NP_389333.1" /db_xref="EnsemblGenomes-Gn:BSU14500" /db_xref="EnsemblGenomes-Tr:CAB13323" /db_xref="GOA:P39759" /db_xref="InterPro:IPR009288" /db_xref="InterPro:IPR013024" /db_xref="InterPro:IPR036568" /db_xref="PDB:2QIK" /db_xref="SubtiList:BG10990" /db_xref="UniProtKB/Swiss-Prot:P39759" /translation="MNSLLFVYGTLRKHEKNHHLLAQSACINEQARTKGSLFAAKEGP TVVFNDEDEGYIYGEVYEADELCIHKLDQFFQGYHKQTVFVETDVGIKIALIYFMNKD GCAGFTKISSGDWKEHQMISKSKNPIYYFAYGSCMDNARFQKAGVDHYFQDPVGRAVL KGYTTRFTLKREDGSRADMLEDGGTTEGVLYRIPYSALSYLYKREGVESLTYRPAFVD VEAGGRHYKDCLTFLVLQKEAEIAPPQHYQIEIERGAELYLSPEFTEKLKRHMNSLPK G*" gene 1519635..1520468 /gene="ykqA" /locus_tag="BSU_14500" /old_locus_tag="BSU14500" promotor_-10 complement(1519801..1519819) /Source="Nicolas_upshift_promotors" /id="U1196" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1080 /SigmaFactorBS="tgtttatgatatccttgaaaaaattgatcgagcttaTGTATA cacaattcatctgctTCATATACTTCGCCATATAtatagccttcatcttcatcattga a" /listShort="S526" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1519816) /Source="Nicolas_upshifts" /id="U1196" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1080 /SigmaFactorBS="tgtttatgatatccttgaaaaaattgatcgagcttaTGTATA cacaattcatctgctTCATATACTTCGCCATATAtatagccttcatcttcatcattga a" /listShort="S526" /GFF_Attribute="listLong" promotor_-35 complement(1519835..1519840) /Source="Nicolas_upshift_promotors" /id="U1196" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1080 /SigmaFactorBS="tgtttatgatatccttgaaaaaattgatcgagcttaTGTATA cacaattcatctgctTCATATACTTCGCCATATAtatagccttcatcttcatcattga a" /listShort="S526" /GFF_Attribute="listLong" /label="promotor_-35" CDS 1520531..1521196 /gene="ktrC" /locus_tag="BSU_14510" /old_locus_tag="BSU14510" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:12562800, 15096624, 22720735, 23963175, 28420751" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12562800, 15096624, 22720735, 23963175, 28420751; Product type t : transporter" /codon_start=1 /transl_table=11 /product="potassium uptake protein" /protein_id="NP_389334.1" /db_xref="EnsemblGenomes-Gn:BSU14510" /db_xref="EnsemblGenomes-Tr:CAB13324" /db_xref="GOA:P39760" /db_xref="InterPro:IPR003148" /db_xref="InterPro:IPR006037" /db_xref="InterPro:IPR036291" /db_xref="InterPro:IPR036721" /db_xref="SubtiList:BG10991" /db_xref="UniProtKB/Swiss-Prot:P39760" /translation="MKKEFAVIGLGRFGGSICKALSEEGVEVMAMDIDEDKVNEYAKI ASHAVIGDSTDESVLKNLGLRNFDHVIVAIGENIQASILTTLILKELGVHTITVKAQN DYHEKVLSKIGADHIVHPERDMAKRIAHNIVSNNVLDYLELSEEHSLVEIVANSRLAG NTLLDLDIRAKYGINIVAIKRGKEVIVSPLATEVIHQEDILIVIGSVTDISRFEKRVL HTK*" gene 1520531..1521196 /gene="ktrC" /locus_tag="BSU_14510" /old_locus_tag="BSU14510" downshifts 1521180 /Source="Nicolas_upshifts" /id="D811" /incds=0 /nref=191 /ntot=256 /MaxReadThrough="3.15176" /MaxDrop="5.50828" /score="4.60161255" /energy="-8.2" /TU="U1195" /idTUdmin="U1195" /TUdmin="-22" /isTUend="TRUE" promotor_-35 1521287..1521293 /Source="Nicolas_upshift_promotors" /id="U1197" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.305694305694306" /psig="0.861138861138861" /xcortree=2383 /SigmaFactorBS="aactgagcgtcaatttcttaaaatttcATTGACTaagcacag gcgttcCGATAGCATATTGTACCATAtaataaaaaaaggaggggcctatttgaataaa g" /listShort="adeC" /GFF_Attribute="listLong" /label="promotor_-35" misc_feature complement(1521308..1521327) /Source="Nicolas_upshift_promotors" /id="U1198" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.584415584415584" /psig="0.985014985014985" /xcortree=1841 /SigmaFactorBS="ttcagcctattgactagcgcttctttattcaaataggcccct cctttttttattaTATGGTACAATATGCTATCGgaacgcctgtgcttagtcaatgaaa t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" promotor_-10 1521308..1521327 /Source="Nicolas_upshift_promotors" /id="U1197" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.305694305694306" /psig="0.861138861138861" /xcortree=2383 /SigmaFactorBS="aactgagcgtcaatttcttaaaatttcATTGACTaagcacag gcgttcCGATAGCATATTGTACCATAtaataaaaaaaggaggggcctatttgaataaa g" /listShort="adeC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1521320 /Source="Nicolas_upshifts" /id="U1197" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.305694305694306" /psig="0.861138861138861" /xcortree=2383 /SigmaFactorBS="aactgagcgtcaatttcttaaaatttcATTGACTaagcacag gcgttcCGATAGCATATTGTACCATAtaataaaaaaaggaggggcctatttgaataaa g" /listShort="adeC" /GFF_Attribute="listLong" upshifts complement(1521322) /Source="Nicolas_upshifts" /id="U1198" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.584415584415584" /psig="0.985014985014985" /xcortree=1841 /SigmaFactorBS="ttcagcctattgactagcgcttctttattcaaataggcccct cctttttttattaTATGGTACAATATGCTATCGgaacgcctgtgcttagtcaatgaaa t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" CDS 1521351..1523084 /gene="adeC" /locus_tag="BSU_14520" /old_locus_tag="BSU14520" /EC_number="3.5.4.2" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:6408059, 8550522, 17183219" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 6408059, 8550522, 17183219; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="adenine deaminase" /protein_id="NP_389335.2" /db_xref="EnsemblGenomes-Gn:BSU14520" /db_xref="EnsemblGenomes-Tr:CAB13325" /db_xref="GOA:P39761" /db_xref="InterPro:IPR006679" /db_xref="InterPro:IPR006680" /db_xref="InterPro:IPR011059" /db_xref="InterPro:IPR026912" /db_xref="InterPro:IPR032466" /db_xref="SubtiList:BG11044" /db_xref="UniProtKB/Swiss-Prot:P39761" /translation="MNKEALVNRLNASAKRQKADIVIKNGKIMDVYNQEWIYEDIAIT DGVIVGLGEYEGENIIDAEGQMIVPGFIDGHVHIESSMVTPIEFAKAVLPHGVTTVVT DPHEIANVSGEKGIEFMLEQARHTPLNIHFMLPSSVPAASFERSGAILKAADLKPFYE EEEVLGLAEVMDYVSVQQAEKDMVQKLLDARVAGKRIDGHLAGLSTDLINIYRTAFVL NDHEVTSKEEALDRIRRGMYVMMREGSVAKNTLNVLPAVNEKNARRFFFCTDDKHVDD LLSEGSVNHQVKMAIQAGLNPFLAYQLGSLNAAECYGLDTKGAIAPGFDADLLFVSDL ENVTVTMTMVKGQTVAEDSKAVYQDHASTAAPDQALLDSVKLAAPLNKQDFHMPIDSE QQINVIQIIPNQLETRLVQVPAPVAREFEPDTELDLLKIAVVERHKGLKETGLGVVKG FGFKSGAIATTISHDSHNIIAVGTNDEDIAAAVNKLQEIGGGLTIIKNGEELHSVPLP IAGLLSDQSAEQVNQSLLTLHDKLSLIGFTGGFNPFLTLSFLALPVIPDIKMTTTGLF DVKSFQHISLQ*" gene 1521351..1523084 /gene="adeC" /locus_tag="BSU_14520" /old_locus_tag="BSU14520" S_feature complement(1522479..1523083) /Source="Nicolas_S_feature" /locus_tag="new_1522479_1523083_c" /HighExp="Etha, C30, C90, dia15, LBGexp, Cold, dia5, S8, G180, S7" /AntisenseName="adeC" /AntisenseCor="-9.8927927273806792E-3" /AntisenseRegPval="-0.1" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S528" downshifts 1523073 /Source="Nicolas_upshifts" /id="D812" /incds=0 /nref=51 /ntot=223 /MaxReadThrough="1.93923" /MaxDrop="6.63088" /score="44.3452043" /energy="-19.5" /TU="NA" /idTUdmin="U1197" /TUdmin="-21" /isTUend="TRUE" CDS complement(1523118..1524785) /gene="rnjA" /locus_tag="BSU_14530" /old_locus_tag="BSU14530" /function="16.3: Control" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:12682299, 15831787, 17005971, 17229210, 17512403, 18713320, 19850915, 21893285, 21893286, 20025672, 22720735, 23504012, 24187087" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12682299, 15831787, 17005971, 17229210, 17512403, 18713320, 19850915, 21893285, 21893286, 20025672, 22720735, 23504012, 24187087; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="ribonuclease J1" /protein_id="NP_389336.1" /db_xref="EnsemblGenomes-Gn:BSU14530" /db_xref="EnsemblGenomes-Tr:CAB13326" /db_xref="GOA:Q45493" /db_xref="InterPro:IPR001279" /db_xref="InterPro:IPR001587" /db_xref="InterPro:IPR004613" /db_xref="InterPro:IPR011108" /db_xref="InterPro:IPR030854" /db_xref="InterPro:IPR036866" /db_xref="PDB:3ZQ4" /db_xref="SubtiList:BG11813" /db_xref="UniProtKB/Swiss-Prot:Q45493" /translation="MKFVKNDQTAVFALGGLGEIGKNTYAVQFQDEIVLIDAGIKFPE DELLGIDYVIPDYTYLVKNEDKIKGLFITHGHEDHIGGIPYLLRQVNIPVYGGKLAIG LLRNKLEEHGLLRQTKLNIIGEDDIVKFRKTAVSFFRTTHSIPDSYGIVVKTPPGNIV HTGDFKFDFTPVGEPANLTKMAEIGKEGVLCLLSDSTNSENPEFTMSERRVGESIHDI FRKVDGRIIFATFASNIHRLQQVIEAAVQNGRKVAVFGRSMESAIEIGQTLGYINCPK NTFIEHNEINRMPANKVTILCTGSQGEPMAALSRIANGTHRQISINPGDTVVFSSSPI PGNTISVSRTINQLYRAGAEVIHGPLNDIHTSGHGGQEEQKLMLRLIKPKFFMPIHGE YRMQKMHVKLATDCGIPEENCFIMDNGEVLALKGDEASVAGKIPSGSVYIDGSGIGDI GNIVLRDRRILSEEGLVIVVVSIDMDDFKISAGPDLISRGFVYMRESGDLINDAQELI SNHLQKVMERKTTQWSEIKNEITDTLAPFLYEKTKRRPMILPIIMEV*" gene complement(1523118..1524785) /gene="rnjA" /locus_tag="BSU_14530" /old_locus_tag="BSU14530" downshifts complement(1523128) /Source="Nicolas_upshifts" /id="D813" /incds=0 /nref=149 /ntot=269 /MaxReadThrough="4.3738" /MaxDrop="8.12983" /score="37.2074215" /energy="-19.5" /TU="U1199" /idTUdmin="U1200" /TUdmin="-2" /isTUend="TRUE" CDS complement(1524791..1525000) /gene="rnpZA" /locus_tag="BSU_14540" /old_locus_tag="BSU14540" /function="9.2: DNA-dependent RNA polymerase" /experiment="publication(s) with functional evidences, PMID:18289874, 24187087" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 18289874, 24187087; Product type f: factor" /codon_start=1 /transl_table=11 /product="omega 1 subunit of RNA polymerase" /protein_id="NP_389337.1" /db_xref="EnsemblGenomes-Gn:BSU14540" /db_xref="EnsemblGenomes-Tr:CAB13327" /db_xref="InterPro:IPR009907" /db_xref="SubtiList:BG13335" /db_xref="UniProtKB/Swiss-Prot:O31718" /translation="MIYKVFYQEKADEVPVREKTDSLYIEGVSERDVRTKLKEKKFNI EFITPVDGAFLEYEQQSENFKVLEL*" gene complement(1524791..1525000) /gene="rnpZA" /locus_tag="BSU_14540" /old_locus_tag="BSU14540" promotor_-10 complement(1525037..1525056) /Source="Nicolas_upshift_promotors" /id="U1199" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.952047952047952" /psig="0.999000999001" /xcortree=2285 /SigmaFactorBS="acaagggatctttcactttttgagagatccttattttgctca aggCTTTccttatattccgttTTCGAATATAATAGAATGAGcgagtctaacatacggc a" /listShort="ykzG, rnjA, S528" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1525059) /Source="Nicolas_upshifts" /id="U1199" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.952047952047952" /psig="0.999000999001" /xcortree=2285 /SigmaFactorBS="acaagggatctttcactttttgagagatccttattttgctca aggCTTTccttatattccgttTTCGAATATAATAGAATGAGcgagtctaacatacggc a" /listShort="ykzG, rnjA, S528" /GFF_Attribute="listLong" S_feature complement(1525061..1525238) /Source="Nicolas_S_feature" /locus_tag="new_1525061_1525238_c" /HighExp="S5, S8, S7, S6, S4, ferm, nit, T5.0H, HiTm, Pyr" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.97062099999999996" /TUshortSig="SigGF" /TUshortPSig="0.828" /TUlongSig="NA" /TUlongPSig="NA" /label="S529" promotor_-35 complement(1525071..1525074) /Source="Nicolas_upshift_promotors" /id="U1199" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.952047952047952" /psig="0.999000999001" /xcortree=2285 /SigmaFactorBS="acaagggatctttcactttttgagagatccttattttgctca aggCTTTccttatattccgttTTCGAATATAATAGAATGAGcgagtctaacatacggc a" /listShort="ykzG, rnjA, S528" /GFF_Attribute="listLong" /label="promotor_-35" upshifts complement(1525239) /Source="Nicolas_upshifts" /id="U1200" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.828171828171828" /psig="0.828171828171828" /xcortree=816 /SigmaFactorBS="aatcatattaaattccattaataaccaCGAAAAGtcttcctc aatctCCGTATACTATTtgtataaaagaactctgggacaaatttttcattaaaggagg g" /listShort="S529, ykzG, rnjA" /GFF_Attribute="listLong" promotor_-10 complement(1525241..1525252) /Source="Nicolas_upshift_promotors" /id="U1200" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.828171828171828" /psig="0.828171828171828" /xcortree=816 /SigmaFactorBS="aatcatattaaattccattaataaccaCGAAAAGtcttcctc aatctCCGTATACTATTtgtataaaagaactctgggacaaatttttcattaaaggagg g" /listShort="S529, ykzG, rnjA" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 complement(1525266..1525272) /Source="Nicolas_upshift_promotors" /id="U1200" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.828171828171828" /psig="0.828171828171828" /xcortree=816 /SigmaFactorBS="aatcatattaaattccattaataaccaCGAAAAGtcttcctc aatctCCGTATACTATTtgtataaaagaactctgggacaaatttttcattaaaggagg g" /listShort="S529, ykzG, rnjA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1525311..1525318 /Source="Nicolas_upshift_promotors" /id="U1201" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.717282717282717" /psig="0.999000999001" /xcortree=1936 /SigmaFactorBS="tttaatatgatttttgaacgaaaTTGTTTGCtgaatgacaat ctTTTTGTATGATGAGGGTGGGaattgcagaccaagacgataaaggggaagttgcgat g" /listShort="ykrA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1525332..1525351 /Source="Nicolas_upshift_promotors" /id="U1201" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.717282717282717" /psig="0.999000999001" /xcortree=1936 /SigmaFactorBS="tttaatatgatttttgaacgaaaTTGTTTGCtgaatgacaat ctTTTTGTATGATGAGGGTGGGaattgcagaccaagacgataaaggggaagttgcgat g" /listShort="ykrA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1525348 /Source="Nicolas_upshifts" /id="U1201" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.717282717282717" /psig="0.999000999001" /xcortree=1936 /SigmaFactorBS="tttaatatgatttttgaacgaaaTTGTTTGCtgaatgacaat ctTTTTGTATGATGAGGGTGGGaattgcagaccaagacgataaaggggaagttgcgat g" /listShort="ykrA" /GFF_Attribute="listLong" CDS 1525386..1526159 /gene="ykrA" /locus_tag="BSU_14550" /old_locus_tag="BSU14550" /EC_number="3.1.3.-" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative hydrolase" /protein_id="NP_389338.1" /db_xref="EnsemblGenomes-Gn:BSU14550" /db_xref="EnsemblGenomes-Tr:CAB13328" /db_xref="GOA:Q45494" /db_xref="InterPro:IPR000150" /db_xref="InterPro:IPR006379" /db_xref="InterPro:IPR023214" /db_xref="InterPro:IPR036412" /db_xref="SubtiList:BG11814" /db_xref="UniProtKB/Swiss-Prot:Q45494" /translation="MDSKLIFFDIDGTIYDHDKNIPESTRKTVAELQRQGHHVFIASG RSPFLVKPILEELGIHSFISYNGQFVVFENQVIYKNPLPENAIRRLLKQADEGKHPVV FMAEDTMKATVADHPHVLEGIGSLKTDYPETDDLFYEGKEIFQLLLFCQDEEEKAYAA FPEFDLVRWHELSTDVLPHGGSKAEGIKKVIERLPFDIGDTYAFGDGLNDLQMIEYVG TGVAMGNAVPELKEIADFVTKPVDEDGIAYAVKELGLLK*" gene 1525386..1526159 /gene="ykrA" /locus_tag="BSU_14550" /old_locus_tag="BSU14550" downshifts 1526130 /Source="Nicolas_upshifts" /id="D814" /incds=0 /nref=184 /ntot=249 /MaxReadThrough="2.83896" /MaxDrop="6.20802" /score="28.5519453" /energy="-15.4" /TU="U1201" /idTUdmin="U1201" /TUdmin="-22" /isTUend="TRUE" CDS complement(1526195..1526749) /gene="defB" /locus_tag="BSU_14560" /old_locus_tag="BSU14560" /EC_number="3.5.1.-" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:11429456, 16207374, 23944997, 26735940" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11429456, 16207374, 23944997, 26735940; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="N-formyl-cysteine deformylase (promiscuous)" /protein_id="NP_389339.1" /db_xref="EnsemblGenomes-Gn:BSU14560" /db_xref="EnsemblGenomes-Tr:CAB13329" /db_xref="GOA:Q45495" /db_xref="InterPro:IPR023635" /db_xref="InterPro:IPR036821" /db_xref="SubtiList:BG11815" /db_xref="UniProtKB/Swiss-Prot:Q45495" /translation="MITMENIVRDGHPALRETAEPVELPPTDAEKQQLADMIEFVKNS QNPELAEKYKLRPGVGLAAPQINIKKRMIAVHAEDASGKLYSYALFNPKIVSHSVEKS YLTSGEGCLSVDEAIPGYVPRYARIRVKGTTLEGENIDIRLKGFPAIVFQHEIDHLNG VMFYDHIDKENPFKEPENAIAIER*" gene complement(1526195..1526749) /gene="defB" /locus_tag="BSU_14560" /old_locus_tag="BSU14560" downshifts complement(1526206) /Source="Nicolas_upshifts" /id="D815" /incds=0 /nref=208 /ntot=265 /MaxReadThrough="1.87469" /MaxDrop="5.89844" /score="28.3817715" /energy="-15.4" /TU="NA" /idTUdmin="U1202" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(1526771..1526790) /Source="Nicolas_upshift_promotors" /id="U1202" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.686313686313686" /psig="0.995004995004995" /xcortree=1852 /SigmaFactorBS="gaccagccatatacggctggtcattcgttTCGTTGCAccttt gtgaagaaaTCCGATATAATTTACATATTaagctttaggagtgaagtttcttgattac t" /listShort="defB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1526781) /Source="Nicolas_upshifts" /id="U1202" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.686313686313686" /psig="0.995004995004995" /xcortree=1852 /SigmaFactorBS="gaccagccatatacggctggtcattcgttTCGTTGCAccttt gtgaagaaaTCCGATATAATTTACATATTaagctttaggagtgaagtttcttgattac t" /listShort="defB" /GFF_Attribute="listLong" promotor_-35 complement(1526805..1526812) /Source="Nicolas_upshift_promotors" /id="U1202" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.686313686313686" /psig="0.995004995004995" /xcortree=1852 /SigmaFactorBS="gaccagccatatacggctggtcattcgttTCGTTGCAccttt gtgaagaaaTCCGATATAATTTACATATTaagctttaggagtgaagtttcttgattac t" /listShort="defB" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 1526834 /Source="Nicolas_upshifts" /id="D816" /incds=0 /nref=1 /ntot=11 /MaxReadThrough="0.95601" /MaxDrop="4.18336" /score="0.455865843" /energy="-17.1" /TU="NA" /idTUdmin="U1201" /TUdmin=682 /isTUend="FALSE" downshifts complement(1526858) /Source="Nicolas_upshifts" /id="D817" /incds=0 /nref=44 /ntot=63 /MaxReadThrough="2.11854" /MaxDrop="8.20445" /score="-8.94821426" /energy="-15.3" /TU="NA" /idTUdmin="U1204" /TUdmin="-14" /isTUend="TRUE" CDS complement(1526859..1527017) /gene="ykzV" /locus_tag="BSU_14569" /old_locus_tag="BSU14569" /function="18: Unknown function" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 20156992, 21670523; Product type f: factor" /codon_start=1 /transl_table=11 /product="putative type I toxin (toxin I motif)" /protein_id="YP_003097725.1" /db_xref="EnsemblGenomes-Gn:BSU14569" /db_xref="EnsemblGenomes-Tr:CAX52616" /db_xref="GOA:C0H409" /db_xref="InterPro:IPR010070" /db_xref="UniProtKB/Swiss-Prot:C0H409" /translation="MYGYGYGGGCCSYGGYGYGGCGYGYGRTFALIVVLFILLIIVGA AYLGGGCC*" gene complement(1526859..1527017) /gene="ykzV" /locus_tag="BSU_14569" /old_locus_tag="BSU14569" CDS complement(1526924..1527067) /locus_tag="BSU_14568" /old_locus_tag="BSU14568" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative antitoxin" /protein_id="YP_009513955.1" /db_xref="EnsemblGenomes-Gn:BSU14568" /db_xref="EnsemblGenomes-Tr:CCQ48596" /db_xref="UniProtKB/TrEMBL:L8E9Z2" /translation="MPTYKGSGVIKRGGYVICMDMVTAEAAAVMVVTDMVAADMATAA PLR*" gene complement(1526924..1527067) /locus_tag="BSU_14568" /old_locus_tag="BSU14568" promotor_-35 1527013..1527017 /Source="Nicolas_upshift_promotors" /id="U1203" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.999000999001" /psig=0 /xcortree=704 /SigmaFactorBS="tccgccgtaaccatatccaTACATattacataaCCTCCTCTT TTAATTacgccagagcctttataagtaggcatagcgtctaatataacctatgtaaaaa c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" S_feature complement(1527018..1527086) /Source="Nicolas_S_feature" /locus_tag="new_1527018_1527086_c" /HighExp="S8, S7, BT, S6, G/S, B36, Pyr, S5, B60, SMMPr" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigK" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S530" promotor_-10 1527027..1527041 /Source="Nicolas_upshift_promotors" /id="U1203" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.999000999001" /psig=0 /xcortree=704 /SigmaFactorBS="tccgccgtaaccatatccaTACATattacataaCCTCCTCTT TTAATTacgccagagcctttataagtaggcatagcgtctaatataacctatgtaaaaa c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1527054 /Source="Nicolas_upshifts" /id="U1203" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.999000999001" /psig=0 /xcortree=704 /SigmaFactorBS="tccgccgtaaccatatccaTACATattacataaCCTCCTCTT TTAATTacgccagagcctttataagtaggcatagcgtctaatataacctatgtaaaaa c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 complement(1527070..1527089) /Source="Nicolas_upshift_promotors" /id="U1204" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1277 /SigmaFactorBS="aaatgcaatactgaaattaaatcaaaaaagtgaaaaatcagg acagatGACCATACAActtttttgttttTACATAGGTTATATTAGACGctatgcctac t" /listShort="S530, ykzV" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1527099) /Source="Nicolas_upshifts" /id="U1204" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1277 /SigmaFactorBS="aaatgcaatactgaaattaaatcaaaaaagtgaaaaatcagg acagatGACCATACAActtttttgttttTACATAGGTTATATTAGACGctatgcctac t" /listShort="S530, ykzV" /GFF_Attribute="listLong" promotor_-35 complement(1527102..1527111) /Source="Nicolas_upshift_promotors" /id="U1204" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1277 /SigmaFactorBS="aaatgcaatactgaaattaaatcaaaaaagtgaaaaatcagg acagatGACCATACAActtttttgttttTACATAGGTTATATTAGACGctatgcctac t" /listShort="S530, ykzV" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1527173..1527180 /Source="Nicolas_upshift_promotors" /id="U1205" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.74025974025974" /psig=1 /xcortree=2147 /SigmaFactorBS="atttaatttcagtattgcatttatacagcacggctATTGCCA AatgtccccatggaTTCTATAGTAGAAATTGTCAagattgggggatttaacgtgaaag a" /listShort="ykyA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1527194..1527213 /Source="Nicolas_upshift_promotors" /id="U1205" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.74025974025974" /psig=1 /xcortree=2147 /SigmaFactorBS="atttaatttcagtattgcatttatacagcacggctATTGCCA AatgtccccatggaTTCTATAGTAGAAATTGTCAagattgggggatttaacgtgaaag a" /listShort="ykyA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1527198 /Source="Nicolas_upshifts" /id="U1205" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.74025974025974" /psig=1 /xcortree=2147 /SigmaFactorBS="atttaatttcagtattgcatttatacagcacggctATTGCCA AatgtccccatggaTTCTATAGTAGAAATTGTCAagattgggggatttaacgtgaaag a" /listShort="ykyA" /GFF_Attribute="listLong" CDS 1527231..1527902 /gene="ykyA" /locus_tag="BSU_14570" /old_locus_tag="BSU14570" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 16684363, 22720735; Product type f: factor" /codon_start=1 /transl_table=11 /product="putative lipoprotein" /protein_id="NP_389340.2" /db_xref="EnsemblGenomes-Gn:BSU14570" /db_xref="EnsemblGenomes-Tr:CAB13330" /db_xref="GOA:P21884" /db_xref="InterPro:IPR019454" /db_xref="InterPro:IPR036785" /db_xref="SubtiList:BG10206" /db_xref="UniProtKB/Swiss-Prot:P21884" /translation="MKDAIKRRPGIKIGAFCAMALILTGCMGQDPVDSLHHSLEKAAE SEKPFQEEQNTLKELEAKENQLYDSVMKLNMDDYKKIVALSNKALENVSKREEHLKLE NDSMKKSETEFEEAKTSAEHIKEKDIKEKADAAANHMEKRYTSYGTMYKEYKKALELN KKLYMQLKDKDLTRDDLDQQIDKVNASYEKILKYSGEFNEQTEKYNKAREDLYDAAGY RVKKS*" gene 1527231..1527902 /gene="ykyA" /locus_tag="BSU_14570" /old_locus_tag="BSU14570" promotor_-35 1527570..1527579 /Source="Nicolas_upshift_promotors" /id="U1206" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.613386613386613" /psig="0.613386613386613" /xcortree=595 /SigmaFactorBS="gcatgaaaaaatcggaaacagaatttGAGGAAGCAAaaacgt cagcggAACATATTAAGGAAAAAGAcataaaagaaaaggccgatgccgcagcaaacca t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1527592..1527610 /Source="Nicolas_upshift_promotors" /id="U1206" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.613386613386613" /psig="0.613386613386613" /xcortree=595 /SigmaFactorBS="gcatgaaaaaatcggaaacagaatttGAGGAAGCAAaaacgt cagcggAACATATTAAGGAAAAAGAcataaaagaaaaggccgatgccgcagcaaacca t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1527604 /Source="Nicolas_upshifts" /id="U1206" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.613386613386613" /psig="0.613386613386613" /xcortree=595 /SigmaFactorBS="gcatgaaaaaatcggaaacagaatttGAGGAAGCAAaaacgt cagcggAACATATTAAGGAAAAAGAcataaaagaaaaggccgatgccgcagcaaacca t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" downshifts 1527849 /Source="Nicolas_upshifts" /id="D818" /incds=0 /nref=96 /ntot=244 /MaxReadThrough="3.9299" /MaxDrop="6.03956" /score="20.6110953" /energy="-9.9" /TU="U1205" /idTUdmin="U1206" /TUdmin=3 /isTUend="TRUE" promotor_-35 1528077..1528082 /Source="Nicolas_upshift_promotors" /id="U1207" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.524475524475524" /psig=1 /xcortree=2692 /SigmaFactorBS="aagcgaatacatttattgaaaatcagcgatgaaaacgATTGA CggttcttctttatttgGTGTAAACTAATCCATGTTAagcggtgttgtattagttttt t" /listShort="S531, pdhA, pdhB, S532, pdhC, pdhD" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1528099..1528118 /Source="Nicolas_upshift_promotors" /id="U1207" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.524475524475524" /psig=1 /xcortree=2692 /SigmaFactorBS="aagcgaatacatttattgaaaatcagcgatgaaaacgATTGA CggttcttctttatttgGTGTAAACTAATCCATGTTAagcggtgttgtattagttttt t" /listShort="S531, pdhA, pdhB, S532, pdhC, pdhD" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 1528100..1528325 /Source="Nicolas_S_feature" /locus_tag="new_1528100_1528325" /HighExp="nit, MG-0.1, Diami, MG-0.2, ferm, dia5, Lbexp, dia0, Paraq, G180" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S531" upshifts 1528100 /Source="Nicolas_upshifts" /id="U1207" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.524475524475524" /psig=1 /xcortree=2692 /SigmaFactorBS="aagcgaatacatttattgaaaatcagcgatgaaaacgATTGA CggttcttctttatttgGTGTAAACTAATCCATGTTAagcggtgttgtattagttttt t" /listShort="S531, pdhA, pdhB, S532, pdhC, pdhD" /GFF_Attribute="listLong" misc_feature complement(1528104..1528123) /Source="Nicolas_upshift_promotors" /id="U1208" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.363636363636364" /psig="0.616383616383616" /xcortree=293 /SigmaFactorBS="tagttacactctgctttgaactgtattatttcgaagttgtaa aaaactaatacaacaCCGCTTAACATGGATTAGTTtacaccaaataaagaagaaccgt c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(1528120) /Source="Nicolas_upshifts" /id="U1208" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.363636363636364" /psig="0.616383616383616" /xcortree=293 /SigmaFactorBS="tagttacactctgctttgaactgtattatttcgaagttgtaa aaaactaatacaacaCCGCTTAACATGGATTAGTTtacaccaaataaagaagaaccgt c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 complement(1528224..1528232) /Source="Nicolas_upshift_promotors" /id="U1209" /multdbtbs="-" /comp="M2" /sig="SigI" /pcomp="0.891108891108891" /psig="0.891108891108891" /xcortree=349 /SigmaFactorBS="tagacgtgcattccttttatacatacaaacttagggTACCCT AAAgtatcagcagtaaGTCGTATTAtattttagccgatccccagtttgccaaaacctt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1528230) /Source="Nicolas_upshifts" /id="U1209" /multdbtbs="-" /comp="M2" /sig="SigI" /pcomp="0.891108891108891" /psig="0.891108891108891" /xcortree=349 /SigmaFactorBS="tagacgtgcattccttttatacatacaaacttagggTACCCT AAAgtatcagcagtaaGTCGTATTAtattttagccgatccccagtttgccaaaacctt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(1528246..1528254) /Source="Nicolas_upshift_promotors" /id="U1209" /multdbtbs="-" /comp="M2" /sig="SigI" /pcomp="0.891108891108891" /psig="0.891108891108891" /xcortree=349 /SigmaFactorBS="tagacgtgcattccttttatacatacaaacttagggTACCCT AAAgtatcagcagtaaGTCGTATTAtattttagccgatccccagtttgccaaaacctt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" CDS 1528326..1529441 /gene="pdhA" /locus_tag="BSU_14580" /old_locus_tag="BSU14580" /EC_number="1.2.4.1" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:1729239, 1784816, 4984174, 6409095, 6815422, 9352926, 9588797, 11976308, 12469342" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1729239, 1784816, 4984174, 6409095, 6815422, 9352926, 9588797, 11976308, 12469342; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="pyruvate dehydrogenase (E1 alpha subunit)" /protein_id="NP_389341.1" /db_xref="EnsemblGenomes-Gn:BSU14580" /db_xref="EnsemblGenomes-Tr:CAB13331" /db_xref="GOA:P21881" /db_xref="InterPro:IPR001017" /db_xref="InterPro:IPR017596" /db_xref="InterPro:IPR029061" /db_xref="SubtiList:BG10207" /db_xref="UniProtKB/Swiss-Prot:P21881" /translation="MAAKTKKAIVDSKKQFDAIKKQFETFQILNEKGEVVNEAAMPDL TDDQLKELMRRMVFTRVLDQRSISLNRQGRLGFYAPTAGQEASQIATHFALEKEDFVL PGYRDVPQLIWHGLPLYQAFLFSRGHFRGNQMPDDVNALSPQIIIGAQYIQTAGVALG LKKRGKKAVAITYTGDGGASQGDFYEGINFAGAYKAPAIFVVQNNRYAISTPVEKQSA AETIAQKAVAAGIVGVQVDGMDPLAVYAATAEARERAINGEGPTLIETLTFRYGPHTM AGDDPTKYRTKEIENEWEQKDPLVRFRAFLENKGLWSEEEEAKVIEDAKEEIKQAIKK ADAEPKQKVTDLMKIMYEKMPHNLEEQFEIYTQKESK*" gene 1528326..1529441 /gene="pdhA" /locus_tag="BSU_14580" /old_locus_tag="BSU14580" CDS 1529445..1530422 /gene="pdhB" /locus_tag="BSU_14590" /old_locus_tag="BSU14590" /EC_number="1.2.4.1" /function="16.3: Control" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:1784816, 9352926, 9588797, 9891797, 10735853, 11976308" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1784816, 9352926, 9588797, 9891797, 10735853, 11976308; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="pyruvate dehydrogenase (E1 beta subunit)" /protein_id="NP_389342.1" /db_xref="EnsemblGenomes-Gn:BSU14590" /db_xref="EnsemblGenomes-Tr:CAB13332" /db_xref="GOA:P21882" /db_xref="InterPro:IPR005475" /db_xref="InterPro:IPR009014" /db_xref="InterPro:IPR029061" /db_xref="InterPro:IPR033248" /db_xref="SubtiList:BG10208" /db_xref="UniProtKB/Swiss-Prot:P21882" /translation="MAQMTMIQAITDALRTELKNDENVLVFGEDVGVNGGVFRATEGL QKEFGEDRVFDTPLAESGIGGLALGLGLNGFRPVMEIQFFGFVYEVMDSVSGQMARMR YRSGGRWTSPVTIRSPFGGGVHTPELHADSLEGLVAQQPGIKVVIPSTPYDAKGLLIS AIRDNDPVVFLEHMKLYRSFRQEVPEEEYTIELGKADVKREGTDLSIITYGAMVHESL KAADELEKDGISAEVVDLRTVSPLDIDTIIASVEKTGRAIVVQEAQKQAGIAANVVAE INDRAILSLEAPVLRVAAPDTVFPFSQAESVWLPNHKDVLETARKVLEF*" gene 1529445..1530422 /gene="pdhB" /locus_tag="BSU_14590" /old_locus_tag="BSU14590" S_feature 1530423..1530536 /Source="Nicolas_S_feature" /locus_tag="new_1530423_1530536" /HighExp="G150, LBGexp, MG-0.1, G180, C30, Diami, Oxctl, G135, ferm, Lbexp" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S532" promotor_-10 complement(1530457..1530476) /Source="Nicolas_upshift_promotors" /id="U1210" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.77022977022977" /psig="0.802197802197802" /xcortree=789 /SigmaFactorBS="ttctcgacctcctagtttgattaagcaattttaaagtttaCA TCgtaagcattgaaaaCAGATATATAATAGAGGGAAaacgttcatcttccctctcgat t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1530474) /Source="Nicolas_upshifts" /id="U1210" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.77022977022977" /psig="0.802197802197802" /xcortree=789 /SigmaFactorBS="ttctcgacctcctagtttgattaagcaattttaaagtttaCA TCgtaagcattgaaaaCAGATATATAATAGAGGGAAaacgttcatcttccctctcgat t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(1530491..1530494) /Source="Nicolas_upshift_promotors" /id="U1210" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.77022977022977" /psig="0.802197802197802" /xcortree=789 /SigmaFactorBS="ttctcgacctcctagtttgattaagcaattttaaagtttaCA TCgtaagcattgaaaaCAGATATATAATAGAGGGAAaacgttcatcttccctctcgat t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" CDS 1530537..1531865 /gene="pdhC" /locus_tag="BSU_14600" /old_locus_tag="BSU14600" /EC_number="2.3.1.12" /function="16.3: Control" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:1784816, 9352926, 9588797, 10735853, 11976308, 22720735, 25355936" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1784816, 9352926, 9588797, 10735853, 11976308, 22720735, 25355936; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="pyruvate dehydrogenase (dihydrolipoamide acetyltransferase E2 subunit)" /protein_id="NP_389343.1" /db_xref="EnsemblGenomes-Gn:BSU14600" /db_xref="EnsemblGenomes-Tr:CAB13333" /db_xref="GOA:P21883" /db_xref="InterPro:IPR000089" /db_xref="InterPro:IPR001078" /db_xref="InterPro:IPR003016" /db_xref="InterPro:IPR004167" /db_xref="InterPro:IPR011053" /db_xref="InterPro:IPR036625" /db_xref="SubtiList:BG10209" /db_xref="UniProtKB/Swiss-Prot:P21883" /translation="MAFEFKLPDIGEGIHEGEIVKWFVKPNDEVDEDDVLAEVQNDKA VVEIPSPVKGKVLELKVEEGTVATVGQTIITFDAPGYEDLQFKGSDESDDAKTEAQVQ STAEAGQDVAKEEQAQEPAKATGAGQQDQAEVDPNKRVIAMPSVRKYAREKGVDIRKV TGSGNNGRVVKEDIDSFVNGGAQEAAPQETAAPQETAAKPAAAPAPEGEFPETREKMS GIRKAIAKAMVNSKHTAPHVTLMDEVDVTNLVAHRKQFKQVAADQGIKLTYLPYVVKA LTSALKKFPVLNTSIDDKTDEVIQKHYFNIGIAADTEKGLLVPVVKNADRKSVFEISD EINGLATKAREGKLAPAEMKGASCTITNIGSAGGQWFTPVINHPEVAILGIGRIAEKA IVRDGEIVAAPVLALSLSFDHRMIDGATAQNALNHIKRLLNDPQLILMEA*" gene 1530537..1531865 /gene="pdhC" /locus_tag="BSU_14600" /old_locus_tag="BSU14600" promotor_-35 1530681..1530688 /Source="Nicolas_upshift_promotors" /id="U1211" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.659340659340659" /psig="0.993006993006993" /xcortree=2451 /SigmaFactorBS="ctgaagtccaaaatgataaagcagtagtagaaattCCTTCAC CtgttaaaggaaaagTATTAGAATTAAAAGTTGAAgagggaacggttgcaactgttgg a" /listShort="pdhD" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1530703..1530722 /Source="Nicolas_upshift_promotors" /id="U1211" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.659340659340659" /psig="0.993006993006993" /xcortree=2451 /SigmaFactorBS="ctgaagtccaaaatgataaagcagtagtagaaattCCTTCAC CtgttaaaggaaaagTATTAGAATTAAAAGTTGAAgagggaacggttgcaactgttgg a" /listShort="pdhD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1530706 /Source="Nicolas_upshifts" /id="U1211" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.659340659340659" /psig="0.993006993006993" /xcortree=2451 /SigmaFactorBS="ctgaagtccaaaatgataaagcagtagtagaaattCCTTCAC CtgttaaaggaaaagTATTAGAATTAAAAGTTGAAgagggaacggttgcaactgttgg a" /listShort="pdhD" /GFF_Attribute="listLong" CDS 1531870..1533282 /gene="pdhD" /locus_tag="BSU_14610" /old_locus_tag="BSU14610" /EC_number="1.8.1.4" /EC_number="1.2.1.25" /function="16.3: Control" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:1784816, 6815422, 9352926, 9588797, 12682299, 21856851" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1784816, 6815422, 9352926, 9588797, 12682299, 21856851; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="dihydrolipoamide dehydrogenase E3 subunit of both pyruvate dehydrogenase and 2-oxoglutarate dehydrogenase complexes" /protein_id="NP_389344.1" /db_xref="EnsemblGenomes-Gn:BSU14610" /db_xref="EnsemblGenomes-Tr:CAB13334" /db_xref="GOA:P21880" /db_xref="InterPro:IPR001100" /db_xref="InterPro:IPR004099" /db_xref="InterPro:IPR006258" /db_xref="InterPro:IPR012999" /db_xref="InterPro:IPR016156" /db_xref="InterPro:IPR023753" /db_xref="InterPro:IPR036188" /db_xref="SubtiList:BG10210" /db_xref="UniProtKB/Swiss-Prot:P21880" /translation="MVVGDFPIETDTLVIGAGPGGYVAAIRAAQLGQKVTVVEKATLG GVCLNVGCIPSKALINAGHRYENAKHSDDMGITAENVTVDFTKVQEWKASVVNKLTGG VAGLLKGNKVDVVKGEAYFVDSNSVRVMDENSAQTYTFKNAIIATGSRPIELPNFKYS ERVLNSTGALALKEIPKKLVVIGGGYIGTELGTAYANFGTELVILEGGDEILPGFEKQ MSSLVTRRLKKKGNVEIHTNAMAKGVEERPDGVTVTFEVKGEEKTVDADYVLITVGRR PNTDELGLEQVGIEMTDRGIVKTDKQCRTNVPNIYAIGDIIEGPPLAHKASYEGKIAA EAIAGEPAEIDYLGIPAVVFSEPELASVGYTEAQAKEEGLDIVAAKFPFAANGRALSL NETDGFMKLITRKEDGLVIGAQIAGASASDMISELSLAIEGGMTAEDIAMTIHAHPTL GEITMEAAEVAIGSPIHIVK*" gene 1531870..1533282 /gene="pdhD" /locus_tag="BSU_14610" /old_locus_tag="BSU14610" downshifts 1533279 /Source="Nicolas_upshifts" /id="D819" /incds=0 /nref=241 /ntot=268 /MaxReadThrough="1.82289" /MaxDrop="9.27853" /score="33.2247807" /energy="-12.1" /TU="NA" /idTUdmin="U1207" /TUdmin="-1" /isTUend="TRUE" CDS complement(1533327..1533701) /gene="slp" /locus_tag="BSU_14620" /old_locus_tag="BSU14620" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:1936936" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1936936; Product type s : structure" /codon_start=1 /transl_table=11 /product="small peptidoglycan-associated lipoprotein" /protein_id="NP_389345.1" /db_xref="EnsemblGenomes-Gn:BSU14620" /db_xref="EnsemblGenomes-Tr:CAB13335" /db_xref="GOA:P39910" /db_xref="SubtiList:BG10211" /db_xref="UniProtKB/Swiss-Prot:P39910" /translation="MRYRAVFPMLIIVFALSGCTLSTINPMKKSRIDNIHHTQILFFS DENQIDQEAPYYDALLDLEKDYPEQIDKMKVYDKKEGWEDEIETVPTLMVVDQRHVVV KIEGCVKKKEDIIKPLQHVLSK*" gene complement(1533327..1533701) /gene="slp" /locus_tag="BSU_14620" /old_locus_tag="BSU14620" downshifts complement(1533375) /Source="Nicolas_upshifts" /id="D820" /incds=0 /nref=26 /ntot=132 /MaxReadThrough="1.54024" /MaxDrop="3.69756" /score="4.23955997" /energy="-12.1" /TU="NA" /idTUdmin="U1212" /TUdmin=3 /isTUend="TRUE" misc_feature complement(1533732..1533751) /Source="Nicolas_upshift_promotors" /id="U1212" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.992007992007992" /psig=1 /xcortree=581 /SigmaFactorBS="ggtttcaattatataacaattaggtaacaagaagcagattaa gccgtctctCGTGATAAACTAAAGCTAGTtaactactgtttatacagaggagaagata g" /listShort="slp" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(1533742) /Source="Nicolas_upshifts" /id="U1212" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.992007992007992" /psig=1 /xcortree=581 /SigmaFactorBS="ggtttcaattatataacaattaggtaacaagaagcagattaa gccgtctctCGTGATAAACTAAAGCTAGTtaactactgtttatacagaggagaagata g" /listShort="slp" /GFF_Attribute="listLong" promotor_-35 1533905..1533910 /Source="Nicolas_upshift_promotors" /id="U1213" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=1078 /SigmaFactorBS="cattcttggatgaaagttcaagaaaacgtGCAATTacattat gtgctgtgGCATATATATCGAGTAAAGcttctgtatgaagaagatattgtatgatgga a" /listShort="S533, ykzW" /listLong="S534, yktA" /label="promotor_-35" promotor_-10 1533926..1533944 /Source="Nicolas_upshift_promotors" /id="U1213" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=1078 /SigmaFactorBS="cattcttggatgaaagttcaagaaaacgtGCAATTacattat gtgctgtgGCATATATATCGAGTAAAGcttctgtatgaagaagatattgtatgatgga a" /listShort="S533, ykzW" /listLong="S534, yktA" /label="promotor_-10" upshifts 1533936 /Source="Nicolas_upshifts" /id="U1213" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=1078 /SigmaFactorBS="cattcttggatgaaagttcaagaaaacgtGCAATTacattat gtgctgtgGCATATATATCGAGTAAAGcttctgtatgaagaagatattgtatgatgga a" /listShort="S533, ykzW" /listLong="S534, yktA" S_feature 1533940..1534049 /Source="Nicolas_S_feature" /locus_tag="new_1533940_1534049" /HighExp="S4, S5, S7, S6, S8, S3, BT, G/S, LoTm, B60" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigEF" /TUshortPSig="0.998" /TUlongSig="NA" /TUlongPSig="NA" /label="S533" downshifts complement(1533972) /Source="Nicolas_upshifts" /id="D821" /incds=0 /nref=4 /ntot=18 /MaxReadThrough="1.96608" /MaxDrop="3.4036" /score="51.898567" /energy="-16.8" /TU="NA" /idTUdmin="U1215" /TUdmin=308 /isTUend="FALSE" promotor_-35 1534033..1534040 /Source="Nicolas_upshift_promotors" /id="U1214" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.967032967032967" /psig=1 /xcortree=346 /SigmaFactorBS="gtgaatatgatgatatgaaataaaatgtgttatacagtttgt TGTTGACAttttaaatgtgacaTATTAATATAATAACAACAAaagaaattaagcgttt t" /listShort="ykzW, S534, yktA" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 1534051 /Source="Nicolas_upshifts" /id="U1214" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.967032967032967" /psig=1 /xcortree=346 /SigmaFactorBS="gtgaatatgatgatatgaaataaaatgtgttatacagtttgt TGTTGACAttttaaatgtgacaTATTAATATAATAACAACAAaagaaattaagcgttt t" /listShort="ykzW, S534, yktA" /GFF_Attribute="listLong" promotor_-10 1534055..1534074 /Source="Nicolas_upshift_promotors" /id="U1214" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.967032967032967" /psig=1 /xcortree=346 /SigmaFactorBS="gtgaatatgatgatatgaaataaaatgtgttatacagtttgt TGTTGACAttttaaatgtgacaTATTAATATAATAACAACAAaagaaattaagcgttt t" /listShort="ykzW, S534, yktA" /GFF_Attribute="listLong" /label="promotor_-10" misc_RNA 1534070..1534280 /gene="srrA" /locus_tag="BSU_misc_RNA_70" /product="small regulatory RNA and messenger RNA (argininemetabolism)" /experiment="publication(s) with functional evidences, PMID:16164558, 17011578, 17020585, 17576690, 18511073, 18586936, 19726675, 20444087, 27449348" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16164558, 17011578, 17020585, 17576690, 18511073, 18586936, 19726675, 20444087, 27449348; Product type n: RNA" /function="16.3: Control" gene 1534070..1534280 /gene="srrA" /locus_tag="BSU_misc_RNA_70" CDS 1534120..1534239 /gene="rgpA" /locus_tag="BSU_14629" /old_locus_tag="BSU14629" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:16164558, 20444087, 27449348" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16164558, 20444087, 27449348; Product type r: regulator" /codon_start=1 /transl_table=11 /product="regulator of GapA synthesis" /protein_id="YP_003097726.1" /db_xref="EnsemblGenomes-Gn:BSU14629" /db_xref="EnsemblGenomes-Tr:CAX52617" /db_xref="InterPro:IPR025236" /db_xref="UniProtKB/Swiss-Prot:C0H410" /translation="MGTIVCQDCNEAIHYFEDEKVTTLYGTCCGQCQCPVDEE*" gene 1534120..1534239 /gene="rgpA" /locus_tag="BSU_14629" /old_locus_tag="BSU14629" downshifts complement(1534126) /Source="Nicolas_upshifts" /id="D822" /incds=0 /nref=6 /ntot=35 /MaxReadThrough="3.43398" /MaxDrop="4.36472" /score="51.898567" /energy="-16.8" /TU="NA" /idTUdmin="U1215" /TUdmin=154 /isTUend="FALSE" downshifts 1534226 /Source="Nicolas_upshifts" /id="D823" /incds=0 /nref=59 /ntot=171 /MaxReadThrough="5.69396" /MaxDrop="7.24152" /score="51.2534618" /energy="-16.8" /TU="U1214" /idTUdmin="U1213" /TUdmin=0 /isTUend="TRUE" S_feature 1534271..1535874 /Source="Nicolas_S_feature" /locus_tag="new_1534271_1535874" /HighExp="M9-stat, M0t90, B60, M40t90, T1.30H, T2.0H, T2.30H, T3.30H, T3.0H, T0.30H" /AntisenseName="speA" /AntisenseCor="-0.33575411980382203" /AntisenseRegPval="-7.8" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="SigEF" /TUlongPSig="0.998" /label="S534" CDS complement(1534279..1535751) /gene="speA" /locus_tag="BSU_14630" /old_locus_tag="BSU14630" /EC_number="4.1.1.19" /function="16.2: Construct biomass (Anabolism)" /function="16.3: Control" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:9723923, 19114526, 19255484, 20876533" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9723923, 19114526, 19255484, 20876533; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="arginine decarboxylase" /protein_id="NP_389346.1" /db_xref="EnsemblGenomes-Gn:BSU14630" /db_xref="EnsemblGenomes-Tr:CAB13336" /db_xref="GOA:P21885" /db_xref="InterPro:IPR000310" /db_xref="InterPro:IPR008286" /db_xref="InterPro:IPR015421" /db_xref="InterPro:IPR015422" /db_xref="InterPro:IPR015424" /db_xref="InterPro:IPR036633" /db_xref="SubtiList:BG10212" /db_xref="UniProtKB/Swiss-Prot:P21885" /translation="MSQHETPLYTGLKKHASRQPVQFHIPGHKKGAGMDPEFRQFIGE NALSIDLINIEPLDDLHAPKGIIKQAQDLAAEAFGADHTFFSVQGTSGAIMTMVMAVC GPGDKIIIPRNVHKSIMTAIVFSGAVPIFIHPEIDNELGISHGITLESAKRALTEHPD AKGLLVINPTYFGVAADLKSIVELAHSFDVPVLVDEAHGVHIHFHDELPLSAMQAGAD IAATSVHKLGGSLTQSSILNMREGLVSKDRVQSILSMLTTTSTSYLLLASLDVARKRL ATEGRQLAEETLKLANQTRDRLNQIEGIYCVGSEILGSKAAYSYDPTKLIISVKSLGL TGHDVEKWLRESFNIEVELSDLYNILCIFTPGDSQNDADRLVEALTEIAQQMSEQDVT HQQTEVLLPEIPLLAMTPRDAFYANTEVIPLKEASGRIIAEFVMVYPPGIPIFIPGEI ITEENISYIFKNLDAGLPVQGPEDSTLHMIRVIKEQKAIQ*" gene complement(1534279..1535751) /gene="speA" /locus_tag="BSU_14630" /old_locus_tag="BSU14630" downshifts complement(1534297) /Source="Nicolas_upshifts" /id="D824" /incds=0 /nref=62 /ntot=198 /MaxReadThrough="3.88498" /MaxDrop="6.76978" /score="51.898567" /energy="-16.8" /TU="NA" /idTUdmin="U1215" /TUdmin="-17" /isTUend="TRUE" S_feature complement(1535752..1535847) /Source="Nicolas_S_feature" /locus_tag="new_1535752_1535847_c" /HighExp="Paraq, G180, LBGexp, Oxctl, G150, G135, C30, H2O2, BMM, dia15" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S535" promotor_-10 complement(1535830..1535849) /Source="Nicolas_upshift_promotors" /id="U1215" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.927072927072927" /psig=1 /xcortree=2477 /SigmaFactorBS="cttaagagaaagcatcttcatttgatcataaattgtTCTTTA CAttctttcaagttcaTAATATAATTCATTTGTTTTacgtctaaaaaacggttgagaa a" /listShort="S535, speA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1535847) /Source="Nicolas_upshifts" /id="U1215" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.927072927072927" /psig=1 /xcortree=2477 /SigmaFactorBS="cttaagagaaagcatcttcatttgatcataaattgtTCTTTA CAttctttcaagttcaTAATATAATTCATTTGTTTTacgtctaaaaaacggttgagaa a" /listShort="S535, speA" /GFF_Attribute="listLong" promotor_-35 1535854..1535857 /Source="Nicolas_upshift_promotors" /id="U1216" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.675324675324675" /psig=1 /xcortree=2377 /SigmaFactorBS="cgttttttagacgtaaaacaaatgaattatattatgaaCTTG aaagaatgtaaagaACAATTTATGATCAAATGAAgatgctttctcttaagggaagtaa a" /listShort="yktA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 complement(1535864..1535871) /Source="Nicolas_upshift_promotors" /id="U1215" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.927072927072927" /psig=1 /xcortree=2477 /SigmaFactorBS="cttaagagaaagcatcttcatttgatcataaattgtTCTTTA CAttctttcaagttcaTAATATAATTCATTTGTTTTacgtctaaaaaacggttgagaa a" /listShort="S535, speA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1535872..1535891 /Source="Nicolas_upshift_promotors" /id="U1216" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.675324675324675" /psig=1 /xcortree=2377 /SigmaFactorBS="cgttttttagacgtaaaacaaatgaattatattatgaaCTTG aaagaatgtaaagaACAATTTATGATCAAATGAAgatgctttctcttaagggaagtaa a" /listShort="yktA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1535876 /Source="Nicolas_upshifts" /id="U1216" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.675324675324675" /psig=1 /xcortree=2377 /SigmaFactorBS="cgttttttagacgtaaaacaaatgaattatattatgaaCTTG aaagaatgtaaagaACAATTTATGATCAAATGAAgatgctttctcttaagggaagtaa a" /listShort="yktA" /GFF_Attribute="listLong" CDS 1535936..1536202 /gene="yktA" /locus_tag="BSU_14640" /old_locus_tag="BSU14640" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 19429628, 22333191" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_389347.1" /db_xref="EnsemblGenomes-Gn:BSU14640" /db_xref="EnsemblGenomes-Tr:CAB13337" /db_xref="InterPro:IPR007920" /db_xref="InterPro:IPR023324" /db_xref="SubtiList:BG11816" /db_xref="UniProtKB/Swiss-Prot:Q45497" /translation="MEYQYPMNEDWTTEEAVDVIAFFQQVELAYEKGADREELLKAYR RFKEIVPGKAEEKKLCGEFEEQSTYSPYRTVKQARESDHAKIKM*" gene 1535936..1536202 /gene="yktA" /locus_tag="BSU_14640" /old_locus_tag="BSU14640" downshifts 1536184 /Source="Nicolas_upshifts" /id="D825" /incds=0 /nref=105 /ntot=250 /MaxReadThrough="2.62284" /MaxDrop="5.09814" /score="40.0811023" /energy="-16.1" /TU="NA" /idTUdmin="U1214" /TUdmin=0 /isTUend="TRUE" CDS complement(1536235..1536873) /gene="yktB" /locus_tag="BSU_14650" /old_locus_tag="BSU14650" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 25643072" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_389348.1" /db_xref="EnsemblGenomes-Gn:BSU14650" /db_xref="EnsemblGenomes-Tr:CAB13338" /db_xref="InterPro:IPR009403" /db_xref="PDB:2A8E" /db_xref="SubtiList:BG11817" /db_xref="UniProtKB/Swiss-Prot:Q45498" /translation="MTQMRFTEEDFNTFTIEGLDARMEVLKETVRPKLTALGEHFAPT LSALTGDEMFPHVAKHARRSVNPPADSWVAFANSKRGYKKLPHFQIGLWESHVFVWFA IIYESPIKEEYGKLLEVNQETITKNIPDSFVWSADHTKPGVHKQSEMDKEQLKTLFER LQTVKKAELLCGIQLQKEEVLNMNNQEFLQRIDDAFKQLAFLYRLTQKVTQA*" gene complement(1536235..1536873) /gene="yktB" /locus_tag="BSU_14650" /old_locus_tag="BSU14650" downshifts complement(1536260) /Source="Nicolas_upshifts" /id="D826" /incds=0 /nref=184 /ntot=257 /MaxReadThrough="2.62959" /MaxDrop="6.54203" /score="26.7765804" /energy="-14.5" /TU="U1217" /idTUdmin="U1217" /TUdmin="-22" /isTUend="TRUE" promotor_-10 complement(1536894..1536913) /Source="Nicolas_upshift_promotors" /id="U1217" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.519480519480519" /psig="0.997002997002997" /xcortree=2002 /SigmaFactorBS="actcgtttattaccacatttctccttacttcaaacgcgctca atctTTTTGaagctcgtatgaacTGTGATAAAATATGTATACTtagcatgaaggagga a" /listShort="yktB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1536918) /Source="Nicolas_upshifts" /id="U1217" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.519480519480519" /psig="0.997002997002997" /xcortree=2002 /SigmaFactorBS="actcgtttattaccacatttctccttacttcaaacgcgctca atctTTTTGaagctcgtatgaacTGTGATAAAATATGTATACTtagcatgaaggagga a" /listShort="yktB" /GFF_Attribute="listLong" promotor_-35 complement(1536928..1536932) /Source="Nicolas_upshift_promotors" /id="U1217" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.519480519480519" /psig="0.997002997002997" /xcortree=2002 /SigmaFactorBS="actcgtttattaccacatttctccttacttcaaacgcgctca atctTTTTGaagctcgtatgaacTGTGATAAAATATGTATACTtagcatgaaggagga a" /listShort="yktB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1536943..1536949 /Source="Nicolas_upshift_promotors" /id="U1218" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=209 /SigmaFactorBS="tttatcacagttcatacgagcttcaaaaagattgagcgCGTT TGAagtaaggagaaatgTGGTAATAAACGAGTAGGTaaacacacaattttcagaatca t" /listShort="S536, ykzI, suhB, ykzC, S537" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1536964..1536982 /Source="Nicolas_upshift_promotors" /id="U1218" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=209 /SigmaFactorBS="tttatcacagttcatacgagcttcaaaaagattgagcgCGTT TGAagtaaggagaaatgTGGTAATAAACGAGTAGGTaaacacacaattttcagaatca t" /listShort="S536, ykzI, suhB, ykzC, S537" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1536965 /Source="Nicolas_upshifts" /id="U1218" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=209 /SigmaFactorBS="tttatcacagttcatacgagcttcaaaaagattgagcgCGTT TGAagtaaggagaaatgTGGTAATAAACGAGTAGGTaaacacacaattttcagaatca t" /listShort="S536, ykzI, suhB, ykzC, S537" /GFF_Attribute="listLong" promotor_-35 1537003..1537012 /Source="Nicolas_upshift_promotors" /id="U1219" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.987012987012987" /psig="0.987012987012987" /xcortree=1258 /SigmaFactorBS="ataaacgagtaggtaaacacacaattttcagaatCATGTTGC GCgtaaatagaacaATCATACGATATAAGAAGTAatcattgttgaatggcaaaatggg a" /listShort="S536, ykzI, suhB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1537025..1537044 /Source="Nicolas_upshift_promotors" /id="U1219" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.987012987012987" /psig="0.987012987012987" /xcortree=1258 /SigmaFactorBS="ataaacgagtaggtaaacacacaattttcagaatCATGTTGC GCgtaaatagaacaATCATACGATATAAGAAGTAatcattgttgaatggcaaaatggg a" /listShort="S536, ykzI, suhB" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 1537029..1537112 /Source="Nicolas_S_feature" /locus_tag="new_1537029_1537112" /HighExp="Etha, S7, M9-stat, S6, S8, BT, Gly, Salt, B60, Sw" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigK, SigB" /TUshortPSig="0.987, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S536" upshifts 1537029 /Source="Nicolas_upshifts" /id="U1219" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.987012987012987" /psig="0.987012987012987" /xcortree=1258 /SigmaFactorBS="ataaacgagtaggtaaacacacaattttcagaatCATGTTGC GCgtaaatagaacaATCATACGATATAAGAAGTAatcattgttgaatggcaaaatggg a" /listShort="S536, ykzI, suhB" /GFF_Attribute="listLong" CDS 1537113..1537301 /gene="ykzI" /locus_tag="BSU_14660" /old_locus_tag="BSU14660" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved general stress protein" /protein_id="NP_389349.1" /db_xref="EnsemblGenomes-Gn:BSU14660" /db_xref="EnsemblGenomes-Tr:CAB13339" /db_xref="SubtiList:BG13337" /db_xref="UniProtKB/Swiss-Prot:O31719" /translation="MRQVVKEGFKEEKNNRVAVWRLEVDYELATLYEAMQKENEEQIE QSKNKLERLRKEWIRLNG*" gene 1537113..1537301 /gene="ykzI" /locus_tag="BSU_14660" /old_locus_tag="BSU14660" downshifts complement(1537118) /Source="Nicolas_upshifts" /id="D827" /incds=0 /nref=1 /ntot=15 /MaxReadThrough="1.50398" /MaxDrop="3.97385" /score="26.7765804" /energy="-14.5" /TU="NA" /idTUdmin="U1220" /TUdmin=0 /isTUend="TRUE" downshifts 1537294 /Source="Nicolas_upshifts" /id="D828" /incds=0 /nref=13 /ntot=45 /MaxReadThrough="7.33866" /MaxDrop="6.12123" /score="-8.73613673" /energy="-8.1" /TU="U1218,U1219" /idTUdmin="U1219" /TUdmin="-628" /isTUend="FALSE" upshifts complement(1537316) /Source="Nicolas_upshifts" /id="U1220" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.616383616383616" /psig="0.105894105894106" /xcortree=118 /SigmaFactorBS="agcaaggaaaatgaaaaatatcccttctcacgtaaaaacgaa ccattcaTGCGgttcgttttcactatcgcttttttacccgttaagacgaatccattct t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" misc_feature complement(1537324..1537327) /Source="Nicolas_upshift_promotors" /id="U1220" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.616383616383616" /psig="0.105894105894106" /xcortree=118 /SigmaFactorBS="agcaaggaaaatgaaaaatatcccttctcacgtaaaaacgaa ccattcaTGCGgttcgttttcactatcgcttttttacccgttaagacgaatccattct t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" promotor_-35 1537371..1537374 /Source="Nicolas_upshift_promotors" /id="U1221" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.519480519480519" /psig=1 /xcortree=1962 /SigmaFactorBS="gttcgtttttacgtgagaagggatatttttcattttcCTTGc tttttcattgccgttATCAGTATCCTATAAAATAAaaggtctacatagaagagaggta c" /listShort="suhB, ykzC, S537" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1537391..1537410 /Source="Nicolas_upshift_promotors" /id="U1221" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.519480519480519" /psig=1 /xcortree=1962 /SigmaFactorBS="gttcgtttttacgtgagaagggatatttttcattttcCTTGc tttttcattgccgttATCAGTATCCTATAAAATAAaaggtctacatagaagagaggta c" /listShort="suhB, ykzC, S537" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1537394 /Source="Nicolas_upshifts" /id="U1221" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.519480519480519" /psig=1 /xcortree=1962 /SigmaFactorBS="gttcgtttttacgtgagaagggatatttttcattttcCTTGc tttttcattgccgttATCAGTATCCTATAAAATAAaaggtctacatagaagagaggta c" /listShort="suhB, ykzC, S537" /GFF_Attribute="listLong" CDS 1537441..1538238 /gene="suhB" /locus_tag="BSU_14670" /old_locus_tag="BSU14670" /EC_number="3.1.3.-" /EC_number="3.1.3.25" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:11914086, 16682444, 22333191, 27784292" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11914086, 16682444, 22333191, 27784292; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="inositol monophosphatase / 5' nucleotidase (purine nucleoside monophosphate)" /protein_id="NP_389350.1" /db_xref="EnsemblGenomes-Gn:BSU14670" /db_xref="EnsemblGenomes-Tr:CAB13340" /db_xref="GOA:Q45499" /db_xref="InterPro:IPR000760" /db_xref="InterPro:IPR020550" /db_xref="InterPro:IPR020583" /db_xref="InterPro:IPR033942" /db_xref="SubtiList:BG11818" /db_xref="UniProtKB/Swiss-Prot:Q45499" /translation="MTNWTEIDEIAKKWIREAGARITQSMHESLTIETKSNPNDLVTN IDKETEKFFIDRIQETFPGHRILGEEGQGDKIHSLEGVVWIIDPIDGTMNFVHQQRNF AISIGIFENGEGKIGLIYDVVHDELYHAFSGRGAYMNETKLAPLKETVIEEAILAINA TWVTENRRIDQSVLAPLVKRVRGTRSYGSAALELANVAAGRIDAYITMRLAPWDYAAG CVLLNEVGGTYTTIEGEPFTFLENHSVLAGNPSIHKTIFEEYLHARK*" gene 1537441..1538238 /gene="suhB" /locus_tag="BSU_14670" /old_locus_tag="BSU14670" CDS 1538264..1538692 /gene="ykzC" /locus_tag="BSU_14680" /old_locus_tag="BSU14680" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 11544224; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative acyltransferase" /protein_id="NP_389351.1" /db_xref="EnsemblGenomes-Gn:BSU14680" /db_xref="EnsemblGenomes-Tr:CAB13341" /db_xref="GOA:O31720" /db_xref="InterPro:IPR000182" /db_xref="InterPro:IPR016181" /db_xref="SubtiList:BG13331" /db_xref="UniProtKB/Swiss-Prot:O31720" /translation="MLEKLAEAHPVWKEEEFGDKDAEDYIISYSMYNGSWLVWEKDGM PVAVSYHLEWSPSNGKPWLGTVLIDPAEEKKGHAKMIIEQISKLLRAKHKAMFAGVPI ERREWILFLSQCGFEQLKTEKDEKGKSFMILVKPLAEAAV*" gene 1538264..1538692 /gene="ykzC" /locus_tag="BSU_14680" /old_locus_tag="BSU14680" downshifts 1538649 /Source="Nicolas_upshifts" /id="D829" /incds=0 /nref=80 /ntot=232 /MaxReadThrough="4.50069" /MaxDrop="4.3098" /score="-9.99315734" /energy="-11.8" /TU="U1218,U1221" /idTUdmin="U1218" /TUdmin="-153" /isTUend="FALSE" S_feature 1538693..1539646 /Source="Nicolas_S_feature" /locus_tag="new_1538693_1539646" /HighExp="H2O2, dia15, Diami, Paraq, G180, G135, G150, dia5, Heat, LBGexp" /AntisenseName="yktD" /AntisenseCor="-1.5120906229522399E-2" /AntisenseRegPval="-0.1" /CDS_PredictionProba="0.117724" /TUshortSig="SigA, SigB" /TUshortPSig="1, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S537" downshifts complement(1538768) /Source="Nicolas_upshifts" /id="D830" /incds=0 /nref=4 /ntot=85 /MaxReadThrough="0.88821" /MaxDrop="3.44773" /score="19.9363134" /energy="-12.8" /TU="NA" /idTUdmin="U1222" /TUdmin=0 /isTUend="TRUE" CDS complement(1538770..1539684) /gene="yktD" /locus_tag="BSU_14690" /old_locus_tag="BSU14690" /EC_number="2.1.1.-" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 17928718; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative AdoMet-dependent methyltransferase" /protein_id="NP_389352.1" /db_xref="EnsemblGenomes-Gn:BSU14690" /db_xref="EnsemblGenomes-Tr:CAB13342" /db_xref="GOA:Q45500" /db_xref="InterPro:IPR007213" /db_xref="InterPro:IPR011610" /db_xref="InterPro:IPR029063" /db_xref="SubtiList:BG11819" /db_xref="UniProtKB/Swiss-Prot:Q45500" /translation="MRKNESSLTSLISAFARAYHSRYDTPLIFDDFIAKDLINEKEFI DISKNMIQEISFFNKEIAERLQNDPEKILKWVAQIQLSPTPLARASYCEKVLHNELIL GAKQYVILGAGLDTFCFRHPELENSLQVFEVDHPATQQLKKNKLKDANLTIPGHLHFV PMDFTKTFSYDPLLDEGFKNTKTFFSLLGVSYYVTREENASLISNLFSHVPPGSSIVF DYADETLFTAKGTSNRVEHMVKMAAASGEPMKSCFTYQEIEHLLESSGLLIYEHLSPD DINDLFFSNRKDNLSAFETIHYIHAVKK*" gene complement(1538770..1539684) /gene="yktD" /locus_tag="BSU_14690" /old_locus_tag="BSU14690" promotor_-10 complement(1539750..1539769) /Source="Nicolas_upshift_promotors" /id="U1222" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.957042957042957" /psig=1 /xcortree=584 /SigmaFactorBS="gatcgcgcgtccagttaagagcaaaaaCATTGACAaaaaaat ttatttaTGCTAAAATTTACTATTAATatatttgtatgtataataagattctcctggc c" /listShort="yktD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1539758) /Source="Nicolas_upshifts" /id="U1222" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.957042957042957" /psig=1 /xcortree=584 /SigmaFactorBS="gatcgcgcgtccagttaagagcaaaaaCATTGACAaaaaaat ttatttaTGCTAAAATTTACTATTAATatatttgtatgtataataagattctcctggc c" /listShort="yktD" /GFF_Attribute="listLong" promotor_-35 complement(1539784..1539791) /Source="Nicolas_upshift_promotors" /id="U1222" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.957042957042957" /psig=1 /xcortree=584 /SigmaFactorBS="gatcgcgcgtccagttaagagcaaaaaCATTGACAaaaaaat ttatttaTGCTAAAATTTACTATTAATatatttgtatgtataataagattctcctggc c" /listShort="yktD" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(1540036..1541601) /gene="nprE" /locus_tag="BSU_14700" /old_locus_tag="BSU14700" /EC_number="3.4.24.28" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:2128597, 6090407, 8436952, 15205417, 26728191" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 2128597, 6090407, 8436952, 15205417, 26728191; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="extracellular neutral metalloprotease" /protein_id="NP_389353.1" /db_xref="EnsemblGenomes-Gn:BSU14700" /db_xref="EnsemblGenomes-Tr:CAB13343" /db_xref="GOA:P68736" /db_xref="InterPro:IPR001570" /db_xref="InterPro:IPR011096" /db_xref="InterPro:IPR013856" /db_xref="InterPro:IPR023612" /db_xref="InterPro:IPR025711" /db_xref="SubtiList:BG10448" /db_xref="UniProtKB/Swiss-Prot:P68736" /translation="MGLGKKLSVAVAASFMSLSISLPGVQAAEGHQLKENQTNFLSKN AIAQSELSAPNDKAVKQFLKKNSNIFKGDPSKRLKLVESTTDALGYKHFRYAPVVNGV PIKDSQVIVHVDKSDNVYAVNGELHNQSAAKTDNSQKVSSEKALALAFKAIGKSPDAV SNGAAKNSNKAELKAIETKDGSYRLAYDVTIRYVEPEPANWEVLVDAETGSILKQQNK VEHAAATGSGTTLKGATVPLNISYEGGKYVLRDLSKPTGTQIITYDLQNRQSRLPGTL VSSTTKTFTSSSQRAAVDAHYNLGKVYDYFYSNFKRNSYDNKGSKIVSSVHYGTQYNN AAWTGDQMIYGDGDGSFFSPLSGSLDVTAHEMTHGVTQETANLIYENQPGALNESFSD VFGYFNDTEDWDIGEDITVSQPALRSLSNPTKYNQPDNYANYRNLPNTDEGDYGGVHT NSGIPNKAAYNTITKLGVSKSQQIYYRALTTYLTPSSTFKDAKAALIQSARDLYGSTD AAKVEAAWNAVGL*" gene complement(1540036..1541601) /gene="nprE" /locus_tag="BSU_14700" /old_locus_tag="BSU14700" promotor_-10 complement(1541636..1541655) /Source="Nicolas_upshift_promotors" /id="U1223" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.526473526473527" /psig="0.993006993006993" /xcortree=3157 /SigmaFactorBS="tactatcaattttgtctagttatgttagtttTTGTTGAGtat tccagaatgcTAGTTTAATATAACAATATAaagttttcagtattttcaaaaaggggga t" /listShort="nprE" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1541647) /Source="Nicolas_upshifts" /id="U1223" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.526473526473527" /psig="0.993006993006993" /xcortree=3157 /SigmaFactorBS="tactatcaattttgtctagttatgttagtttTTGTTGAGtat tccagaatgcTAGTTTAATATAACAATATAaagttttcagtattttcaaaaaggggga t" /listShort="nprE" /GFF_Attribute="listLong" promotor_-35 complement(1541669..1541676) /Source="Nicolas_upshift_promotors" /id="U1223" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.526473526473527" /psig="0.993006993006993" /xcortree=3157 /SigmaFactorBS="tactatcaattttgtctagttatgttagtttTTGTTGAGtat tccagaatgcTAGTTTAATATAACAATATAaagttttcagtattttcaaaaaggggga t" /listShort="nprE" /GFF_Attribute="listLong" /label="promotor_-35" CDS 1541886..1543826 /gene="ylaA" /locus_tag="BSU_14710" /old_locus_tag="BSU14710" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 16501307" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_389354.1" /db_xref="EnsemblGenomes-Gn:BSU14710" /db_xref="EnsemblGenomes-Tr:CAB13344" /db_xref="GOA:O07625" /db_xref="SubtiList:BG13338" /db_xref="UniProtKB/Swiss-Prot:O07625" /translation="MLFVLELFSHYVLHFERYFILSRQSTLLIQWSIVVLAGLYLLVH HPKINRQRTMFLAGVILRIVLLAGVSVELIHQVQSTNFTSAYLREDGKELLPLLHFLL YGYVLLTAFHYMLMPRDHGGKGKFYTFDLAVVSLPIVQMIFSFFSYWKEYPDGMEPIA FVFLFFIITLPIALNVVFFKLYWRTDKILLGLFYTLIIGLLVLLLAPYPNQISKDYGA VMPYTIYLAMAGFLMSYHLFQKSGKVYVRVNKWVTMAVMVFFVLLLNPIYNIGTAAFA VSKPANVHDSFNFVGEHISSEKAEQILKSFFPTDETLYLHDTNMDVHYFYSFESKGYK AEVDEVSQLIRNYEYLQKAHGKKLTNQEYKRKSIAFLERHGRVLHKDHIETKVSQEDG QTVVRIYLKNQLHKKDHADDGAVFYWEKETLMGFSEDPSIYQLDSLLHVHITEQDIHD KVEQMFTALNISKQPYQITDIESDSLLGSMVRVETKVGIVLEFEGESGCLHSLSLPMK KNISMANSRLQHQILSIFDARGSEKKKKSSQGDMVMYTDSSKTYEFVEAQGQLNVYVY SDTPDQSFPYTYRNGTLAYEKVASLYQDVIYKKRMRPIIVQRGDERHYAWLIIIQPFG SNRHDAYVVDGETQEVKSLYES*" gene 1541886..1543826 /gene="ylaA" /locus_tag="BSU_14710" /old_locus_tag="BSU14710" CDS 1543816..1544085 /gene="ylaB" /locus_tag="BSU_14720" /old_locus_tag="BSU14720" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function; PubMedId : 16501307" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="NP_389355.1" /db_xref="EnsemblGenomes-Gn:BSU14720" /db_xref="EnsemblGenomes-Tr:CAB13345" /db_xref="GOA:O07626" /db_xref="SubtiList:BG13339" /db_xref="UniProtKB/Swiss-Prot:O07626" /translation="MNHKEKESVFVDLYDLYKEGELEDESMEWMKQHESLFQKNAEDL KSKTCLKRSPGAEEESQIRYMKVYLSSMYICFILLAIWMTVWFYF*" gene 1543816..1544085 /gene="ylaB" /locus_tag="BSU_14720" /old_locus_tag="BSU14720" promotor_-35 1544051..1544055 /Source="Nicolas_upshift_promotors" /id="U1224" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.312687312687313" /psig="0.985014985014985" /xcortree=2008 /SigmaFactorBS="gtcttccatgtatatctgtttcattttatTGGCCaTTtggat gacggTGTGGTTTTATTTTTAATGAagcatagggattccattgaggacttgtatcggc a" /listShort="ylaC, ylaD" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1544069..1544088 /Source="Nicolas_upshift_promotors" /id="U1224" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.312687312687313" /psig="0.985014985014985" /xcortree=2008 /SigmaFactorBS="gtcttccatgtatatctgtttcattttatTGGCCaTTtggat gacggTGTGGTTTTATTTTTAATGAagcatagggattccattgaggacttgtatcggc a" /listShort="ylaC, ylaD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1544082 /Source="Nicolas_upshifts" /id="U1224" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.312687312687313" /psig="0.985014985014985" /xcortree=2008 /SigmaFactorBS="gtcttccatgtatatctgtttcattttatTGGCCaTTtggat gacggTGTGGTTTTATTTTTAATGAagcatagggattccattgaggacttgtatcggc a" /listShort="ylaC, ylaD" /GFF_Attribute="listLong" CDS 1544085..1544606 /gene="sigP" /locus_tag="BSU_14730" /old_locus_tag="BSU14730" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:16501307, 16728958, 20817771" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16501307, 16728958, 20817771; Product type r: regulator" /codon_start=1 /transl_table=11 /product="RNA polymerase ECF-type sigma factor" /protein_id="NP_389356.1" /db_xref="EnsemblGenomes-Gn:BSU14730" /db_xref="EnsemblGenomes-Tr:CAB13346" /db_xref="GOA:O07627" /db_xref="InterPro:IPR007627" /db_xref="InterPro:IPR013249" /db_xref="InterPro:IPR013324" /db_xref="InterPro:IPR013325" /db_xref="InterPro:IPR014284" /db_xref="InterPro:IPR014296" /db_xref="InterPro:IPR036388" /db_xref="SubtiList:BG13340" /db_xref="UniProtKB/Swiss-Prot:O07627" /translation="MKHRDSIEDLYRQYYQEILNYLFRRTHHLETAKDLAQDTFVKAL NGLASFRGHSSIRTWLYTIAHHTFINWYRRDVKYQFTEISKNEGLTQTTYDQPEQYLS RTVKSETLRQELLKLKDQHQSVLILREFQELSYEEIAEILGWSLSKVNTTLHRARLEL KKNMTKSREEERI*" gene 1544085..1544606 /gene="sigP" /locus_tag="BSU_14730" /old_locus_tag="BSU14730" CDS 1544603..1544896 /gene="sigQ" /locus_tag="BSU_14740" /old_locus_tag="BSU14740" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:16501307, 16728958, 20817771" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16501307, 16728958, 20817771; Product type r: regulator" /codon_start=1 /transl_table=11 /product="anti-SigP(YlaC) sigma factor" /protein_id="NP_389357.1" /db_xref="EnsemblGenomes-Gn:BSU14740" /db_xref="EnsemblGenomes-Tr:CAB13347" /db_xref="GOA:O07628" /db_xref="InterPro:IPR027383" /db_xref="SubtiList:BG13341" /db_xref="UniProtKB/Swiss-Prot:O07628" /translation="MTCFLVRDLLPLYLEGDCKRETEHVIEEHLKMCSSCRDMYDTMA EPFELESEQAVEEAYLPEEELRFKQRYYGLLIMKAACWFGAAVAMMLIIKLLI*" gene 1544603..1544896 /gene="sigQ" /locus_tag="BSU_14740" /old_locus_tag="BSU14740" CDS complement(1544936..1545547) /gene="ylaE" /locus_tag="BSU_14750" /old_locus_tag="BSU14750" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type f: factor" /codon_start=1 /transl_table=11 /product="putative exported protein" /protein_id="NP_389358.1" /db_xref="EnsemblGenomes-Gn:BSU14750" /db_xref="EnsemblGenomes-Tr:CAB13348" /db_xref="SubtiList:BG13342" /db_xref="UniProtKB/Swiss-Prot:O07629" /translation="MKKTFVKKAMLTTAAMTSAALLTFGPDAASAKTPVDNTAVQLQH QASTNEDLNTFIDILNQCIYEQDGVYYFDSEKAVELGMTKEEAQVIATLWESTSEFFS IVSQCVYLEDGNYKFDTEKAVELGFTEKEALALEQFFSAVSLKIHILQAAIVLQDDVY SYDKDAALQAGATPLQADVYEKLFSALSQEQLAAIYDMIHPQA*" gene complement(1544936..1545547) /gene="ylaE" /locus_tag="BSU_14750" /old_locus_tag="BSU14750" downshifts complement(1544950) /Source="Nicolas_upshifts" /id="D831" /incds=0 /nref=44 /ntot=184 /MaxReadThrough="1.37453" /MaxDrop="4.23106" /score="20.8244305" /energy="-11.7" /TU="NA" /idTUdmin="U1225" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(1545579..1545598) /Source="Nicolas_upshift_promotors" /id="U1225" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.616383616383616" /psig="0.956043956043956" /xcortree=3078 /SigmaFactorBS="ggcaacgatacacataaaataccatagcgcctATTCctccac cggaaactACTCCCTATAATGGAATTTGtagcacaattcataaaagggagagaagaaa c" /listShort="ylaE" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1545588) /Source="Nicolas_upshifts" /id="U1225" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.616383616383616" /psig="0.956043956043956" /xcortree=3078 /SigmaFactorBS="ggcaacgatacacataaaataccatagcgcctATTCctccac cggaaactACTCCCTATAATGGAATTTGtagcacaattcataaaagggagagaagaaa c" /listShort="ylaE" /GFF_Attribute="listLong" promotor_-35 complement(1545613..1545616) /Source="Nicolas_upshift_promotors" /id="U1225" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.616383616383616" /psig="0.956043956043956" /xcortree=3078 /SigmaFactorBS="ggcaacgatacacataaaataccatagcgcctATTCctccac cggaaactACTCCCTATAATGGAATTTGtagcacaattcataaaagggagagaagaaa c" /listShort="ylaE" /GFF_Attribute="listLong" /label="promotor_-35" downshifts complement(1545803) /Source="Nicolas_upshifts" /id="D832" /incds=0 /nref=18 /ntot=138 /MaxReadThrough="2.72081" /MaxDrop="5.25382" /score="5.78870736" /energy="-8.3" /TU="NA" /idTUdmin="U1226" /TUdmin="-17" /isTUend="TRUE" CDS complement(1545820..1546008) /gene="ylaF" /locus_tag="BSU_14760" /old_locus_tag="BSU14760" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_389359.1" /db_xref="EnsemblGenomes-Gn:BSU14760" /db_xref="EnsemblGenomes-Tr:CAB13349" /db_xref="GOA:O07630" /db_xref="InterPro:IPR035211" /db_xref="SubtiList:BG13343" /db_xref="UniProtKB/Swiss-Prot:O07630" /translation="MKKMNWLLLLFAFAAVFSIMLIGVFIAEKSPAGIIASIVLVCAV MGGGFTLKKKMREQGLLD*" gene complement(1545820..1546008) /gene="ylaF" /locus_tag="BSU_14760" /old_locus_tag="BSU14760" downshifts complement(1545874) /Source="Nicolas_upshifts" /id="D833" /incds=0 /nref=9 /ntot=204 /MaxReadThrough="4.38484" /MaxDrop="3.2214" /score="5.78870736" /energy="-8.3" /TU="U1226" /idTUdmin="U1226" /TUdmin="-88" /isTUend="FALSE" promotor_-10 complement(1546030..1546049) /Source="Nicolas_upshift_promotors" /id="U1226" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.531468531468531" /psig=1 /xcortree=3095 /SigmaFactorBS="aaaaaaattagataactttcatattatatcacacatccTCTT TAAAagcgtcacgtttTTCTGTAAACTTAATATAAGacgtaaaaggggatggaattta t" /listShort="ylaF" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1546047) /Source="Nicolas_upshifts" /id="U1226" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.531468531468531" /psig=1 /xcortree=3095 /SigmaFactorBS="aaaaaaattagataactttcatattatatcacacatccTCTT TAAAagcgtcacgtttTTCTGTAAACTTAATATAAGacgtaaaaggggatggaattta t" /listShort="ylaF" /GFF_Attribute="listLong" promotor_-35 complement(1546062..1546069) /Source="Nicolas_upshift_promotors" /id="U1226" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.531468531468531" /psig=1 /xcortree=3095 /SigmaFactorBS="aaaaaaattagataactttcatattatatcacacatccTCTT TAAAagcgtcacgtttTTCTGTAAACTTAATATAAGacgtaaaaggggatggaattta t" /listShort="ylaF" /GFF_Attribute="listLong" /label="promotor_-35" misc_feature 1546075..1546094 /Source="Nicolas_upshift_promotors" /id="U1227" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.63936063936064" /psig=1 /xcortree=2497 /SigmaFactorBS="ttttacgtcttatattaagtttacagaaaaacgtgacgcttt taaagaggatgTGTGATATAATATGAAAGTTatctaatttttttaggagatgaaaaag t" /listShort="bipA, ylaH" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 1546082 /Source="Nicolas_upshifts" /id="U1227" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.63936063936064" /psig=1 /xcortree=2497 /SigmaFactorBS="ttttacgtcttatattaagtttacagaaaaacgtgacgcttt taaagaggatgTGTGATATAATATGAAAGTTatctaatttttttaggagatgaaaaag t" /listShort="bipA, ylaH" /GFF_Attribute="listLong" CDS 1546121..1547959 /gene="bipA" /locus_tag="BSU_14770" /old_locus_tag="BSU14770" /function="16.3: Control" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 11683274, 12399512, 9642082, 25135187, 26283392; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="ribosome-associated GTPase" /protein_id="NP_389360.1" /db_xref="EnsemblGenomes-Gn:BSU14770" /db_xref="EnsemblGenomes-Tr:CAB13350" /db_xref="GOA:O07631" /db_xref="InterPro:IPR000640" /db_xref="InterPro:IPR000795" /db_xref="InterPro:IPR004161" /db_xref="InterPro:IPR005225" /db_xref="InterPro:IPR006298" /db_xref="InterPro:IPR009000" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR031157" /db_xref="InterPro:IPR035647" /db_xref="InterPro:IPR035651" /db_xref="SubtiList:BG13344" /db_xref="UniProtKB/Swiss-Prot:O07631" /translation="MKLRNDLRNIAIIAHVDHGKTTLVDQLLHQAGTFRANEQVAERA MDSNDLERERGITILAKNTAINYKDTRINILDTPGHADFGGEVERIMKMVDGVVLVVD AYEGCMPQTRFVLKKALEQNLNPVVVVNKIDRDFARPEEVIDEVLDLFIELDANEEQL EFPVVYASAINGTASLDPKQQDENMEALYETIIKHVPAPVDNAEEPLQFQVALLDYND YVGRIGIGRVFRGTMKVGQQVSLMKLDGTAKSFRVTKIFGFQGLKRVEIEEAKAGDLV AVSGMEDINVGETVCPVDHQDPLPVLRIDEPTLQMTFVVNNSPFAGREGKYVTARKIE ERLQSQLQTDVSLRVEPTASPDAWVVSGRGELHLSILIENMRREGYELQVSKPEVIIK EIDGVRCEPVERVQIDVPEEHTGSVMESMGARKGEMVDMINNGNGQVRLIFTVPSRGL IGYSTEFLSLTRGFGILNHTFDSYQPMQAGQVGGRRQGVLVSMENGKATSYGIQGIED RGVIFVEPGTEVYEGMIVGEHNRDNDLVVNVSKMKQQTNVRSATKDQTTTIKKARIMS LEESLEYLNEDEYCEVTPESIRLRKKILNKNEREKAAKKKKTAGLS*" gene 1546121..1547959 /gene="bipA" /locus_tag="BSU_14770" /old_locus_tag="BSU14770" CDS 1548016..1548333 /gene="ylaH" /locus_tag="BSU_14780" /old_locus_tag="BSU14780" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved membrane protein of unkown function" /protein_id="NP_389361.1" /db_xref="EnsemblGenomes-Gn:BSU14780" /db_xref="EnsemblGenomes-Tr:CAB13351" /db_xref="GOA:O07632" /db_xref="InterPro:IPR025620" /db_xref="SubtiList:BG13345" /db_xref="UniProtKB/Swiss-Prot:O07632" /translation="MNDVSERLSFFAALYQVDRQPAAGMWLLYGTIFVLAVIVFKLGF AKRLPVLKSAVVYVFLALGCTVLTFLGVFLPVAEGLVVAALILIIYKIRLYQSKKGQS AKS*" gene 1548016..1548333 /gene="ylaH" /locus_tag="BSU_14780" /old_locus_tag="BSU14780" downshifts 1548307 /Source="Nicolas_upshifts" /id="D834" /incds=0 /nref=241 /ntot=297 /MaxReadThrough="2.76511" /MaxDrop="7.50514" /score="29.8701447" /energy="-12.5" /TU="NA" /idTUdmin="U1227" /TUdmin="-21" /isTUend="TRUE" downshifts complement(1548382) /Source="Nicolas_upshifts" /id="D835" /incds=0 /nref=240 /ntot=265 /MaxReadThrough="0.672690000000001" /MaxDrop="7.03405" /score="10.4340016" /energy="-12.5" /TU="NA" /idTUdmin="U1228" /TUdmin=0 /isTUend="TRUE" CDS complement(1548389..1548598) /gene="ylaI" /locus_tag="BSU_14790" /old_locus_tag="BSU14790" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_389362.1" /db_xref="EnsemblGenomes-Gn:BSU14790" /db_xref="EnsemblGenomes-Tr:CAB13352" /db_xref="InterPro:IPR019241" /db_xref="SubtiList:BG13346" /db_xref="UniProtKB/Swiss-Prot:O07633" /translation="MMRVKCSICDKIETIDDDTLIAKRLRNRPIHTYMCQECHDRIAK KTEERLKTGKFTFHPGQQKKEKVKK*" gene complement(1548389..1548598) /gene="ylaI" /locus_tag="BSU_14790" /old_locus_tag="BSU14790" misc_feature complement(1548612..1548631) /Source="Nicolas_upshift_promotors" /id="U1228" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.742257742257742" /psig=1 /xcortree=1900 /SigmaFactorBS="tgactaagctatagccttgcgctttagctttttcttattttg gacagcttctgatcCGTGGTATAATACATGTTAGtgaaagaggtgatatgatgagggt c" /listShort="ylaI" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(1548627) /Source="Nicolas_upshifts" /id="U1228" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.742257742257742" /psig=1 /xcortree=1900 /SigmaFactorBS="tgactaagctatagccttgcgctttagctttttcttattttg gacagcttctgatcCGTGGTATAATACATGTTAGtgaaagaggtgatatgatgagggt c" /listShort="ylaI" /GFF_Attribute="listLong" CDS complement(1548681..1549310) /gene="ylaJ" /locus_tag="BSU_14800" /old_locus_tag="BSU14800" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 28333204; Product type lp: lipoprotein" /codon_start=1 /transl_table=11 /product="putative germination lipoprotein" /protein_id="NP_389363.1" /db_xref="EnsemblGenomes-Gn:BSU14800" /db_xref="EnsemblGenomes-Tr:CAB13353" /db_xref="GOA:O07634" /db_xref="InterPro:IPR014247" /db_xref="InterPro:IPR015943" /db_xref="InterPro:IPR019076" /db_xref="SubtiList:BG13347" /db_xref="UniProtKB/Swiss-Prot:O07634" /translation="MRILFIIIQLTLILSACAYQQGKQGQNVEKESTRQQETKPIHVK DTTQETKDNGTRTDIAKHLVSVAEKNPDVKDATAVVLGGYAVVGIDVDDTLDRSKVET IKYSVAQALKNDRYGANAVVIADPDTVSRLREMSREISEGHPVTGILDELAAIVGRVL PEVPNDVIDNEDEPQTKQQNDQLNRKQQQEMEKEQNDQSDHHMKKNNND*" gene complement(1548681..1549310) /gene="ylaJ" /locus_tag="BSU_14800" /old_locus_tag="BSU14800" downshifts complement(1548712) /Source="Nicolas_upshifts" /id="D836" /incds=0 /nref=57 /ntot=112 /MaxReadThrough="1.90936" /MaxDrop="5.8475" /score="3.85709048" /energy="-7.2" /TU="NA" /idTUdmin="U1229" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(1549212..1549230) /Source="Nicolas_upshift_promotors" /id="U1229" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp=1 /psig=1 /xcortree=545 /SigmaFactorBS="acttatcctgtccgcttgtgcctatcaaCAAGGAAAAcaggg ccagaaTGTTGAAAAAGAATCAACAagacagcaggagactaaaccgattcacgtaaag g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1549218) /Source="Nicolas_upshifts" /id="U1229" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp=1 /psig=1 /xcortree=545 /SigmaFactorBS="acttatcctgtccgcttgtgcctatcaaCAAGGAAAAcaggg ccagaaTGTTGAAAAAGAATCAACAagacagcaggagactaaaccgattcacgtaaag g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(1549242..1549250) /Source="Nicolas_upshift_promotors" /id="U1229" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp=1 /psig=1 /xcortree=545 /SigmaFactorBS="acttatcctgtccgcttgtgcctatcaaCAAGGAAAAcaggg ccagaaTGTTGAAAAAGAATCAACAagacagcaggagactaaaccgattcacgtaaag g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(1549345..1549356) /Source="Nicolas_upshift_promotors" /id="U1230" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=936 /SigmaFactorBS="aaaggtgaatgcctgctaaaatatatgtttttgTGCATAAag atagaaggttaaTTCAACAATAAAattaatgaaagcattttaaggagggaacccgcaa g" /listShort="ylaJ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1549350) /Source="Nicolas_upshifts" /id="U1230" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=936 /SigmaFactorBS="aaaggtgaatgcctgctaaaatatatgtttttgTGCATAAag atagaaggttaaTTCAACAATAAAattaatgaaagcattttaaggagggaacccgcaa g" /listShort="ylaJ" /GFF_Attribute="listLong" promotor_-35 1549362..1549367 /Source="Nicolas_upshift_promotors" /id="U1231" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1153 /SigmaFactorBS="tccttaaaatgctttcattaattttattgttgaattaacCTT CTAtctttatgcacaaaaACATATATTTTAGCAGGCAttcacctttttcatcaaaaga g" /listShort="S538, ylaK, S540, glsB" /listLong="ylaN, S541, ftsW, pycA" /label="promotor_-35" promotor_-35 complement(1549371..1549377) /Source="Nicolas_upshift_promotors" /id="U1230" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=936 /SigmaFactorBS="aaaggtgaatgcctgctaaaatatatgtttttgTGCATAAag atagaaggttaaTTCAACAATAAAattaatgaaagcattttaaggagggaacccgcaa g" /listShort="ylaJ" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1549383..1549401 /Source="Nicolas_upshift_promotors" /id="U1231" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1153 /SigmaFactorBS="tccttaaaatgctttcattaattttattgttgaattaacCTT CTAtctttatgcacaaaaACATATATTTTAGCAGGCAttcacctttttcatcaaaaga g" /listShort="S538, ylaK, S540, glsB" /listLong="ylaN, S541, ftsW, pycA" /label="promotor_-10" upshifts 1549383 /Source="Nicolas_upshifts" /id="U1231" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1153 /SigmaFactorBS="tccttaaaatgctttcattaattttattgttgaattaacCTT CTAtctttatgcacaaaaACATATATTTTAGCAGGCAttcacctttttcatcaaaaga g" /listShort="S538, ylaK, S540, glsB" /listLong="ylaN, S541, ftsW, pycA" S_feature 1549384..1549464 /Source="Nicolas_S_feature" /locus_tag="new_1549384_1549464" /HighExp="S3, S5, S4, S8, S6, S7, LoTm, T5.0H, B36, BT" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigEF" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S538" CDS 1549465..1550793 /gene="ylaK" /locus_tag="BSU_14810" /old_locus_tag="BSU14810" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 12762842, 17114254; Product type f: factor" /codon_start=1 /transl_table=11 /product="putative phosphate starvation inducible protein" /protein_id="NP_389364.1" /db_xref="EnsemblGenomes-Gn:BSU14810" /db_xref="EnsemblGenomes-Tr:CAB13354" /db_xref="GOA:O07635" /db_xref="InterPro:IPR002716" /db_xref="InterPro:IPR003714" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR029060" /db_xref="SubtiList:BG13348" /db_xref="UniProtKB/Swiss-Prot:O07635" /translation="MSKIYVLDTNVLLQDPNAIFSFEENEVVIPAVVLEEVDSKKRYM DEVGRNARHVSKLIDALRQKGRLHEHVPLDTGGTLRIELNHRSFHQLQEIFIEKTNDN RILAVAKNLSLEEETKENGRPVILVSKDVLVRVKADAIGLLAEDFLNDRVVDNDEMYS GYKDLYISQQLFSSFYGKNQISVNDVKQHAFYPNQFALMKDELGGSSSAVGIADKTGT VLKRLVFDDEHIWGIRPKNVQQTMALELLLREDIPLVTLIGKAGTGKTLLALAAGLLQ TEDLGIYKKLVVARPIVPVGKDIGYLPGEKEEKLKPWMQPIFDNLEFLFNAKKPGELD AILAGIGSIQVEALTYIRGRSIPDQFIIIDEAQNLTRHEVKTLLTRVGEGSKIVLMGD PEQIDHPYLDSLNNGLAYVVERFKGQPISGSVKLLKGERSGLAQLAADLL*" gene 1549465..1550793 /gene="ylaK" /locus_tag="BSU_14810" /old_locus_tag="BSU14810" S_feature complement(1550649..1550796) /Source="Nicolas_S_feature" /locus_tag="new_1550649_1550796_c" /HighExp="M40t90, M0t90, dia15, Lbtran, dia5, Etha, Mt0, Gly, LBGtran, LPhT" /AntisenseName="ylaK" /AntisenseCor="-0.66426410013570203" /AntisenseRegPval="-34.9" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.987" /TUlongSig="NA" /TUlongPSig="NA" /label="S539" downshifts complement(1550692) /Source="Nicolas_upshifts" /id="D837" /incds=1 /nref=6 /ntot=67 /MaxReadThrough="3.81309" /MaxDrop="3.44499" /score="3.85709048" /energy="-7.2" /TU="U1232" /idTUdmin="U1232" /TUdmin="-198" /isTUend="FALSE" S_feature 1550794..1551384 /Source="Nicolas_S_feature" /locus_tag="new_1550794_1551384" /HighExp="S3, S4, S6, S5, S8, S7, BT, B36, LoTm, T5.0H" /AntisenseName="ylaL" /AntisenseCor="-0.79954210237955903" /AntisenseRegPval="-60.3" /CDS_PredictionProba="NA" /TUshortSig="SigEF" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S540" CDS complement(1550797..1551282) /gene="ylaL" /locus_tag="BSU_14820" /old_locus_tag="BSU14820" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_389365.1" /db_xref="EnsemblGenomes-Gn:BSU14820" /db_xref="EnsemblGenomes-Tr:CAB13355" /db_xref="GOA:O07636" /db_xref="InterPro:IPR020229" /db_xref="InterPro:IPR036374" /db_xref="SubtiList:BG13349" /db_xref="UniProtKB/Swiss-Prot:O07636" /translation="MSVIQVKGNVTYPITIDPSVWIFDDRKFSFDRKGDSQDTYLQSA GDESDLDPERVIREGRIAPPTLKTEKQYEKQKLMNGSFAMRLGTVLKNAEPNSSATQC VFVTSSGKAAVSLETALNSIVHFSEAGKPIQEGGPVHIYFEDPVHHKQPITDVKEIEI I*" gene complement(1550797..1551282) /gene="ylaL" /locus_tag="BSU_14820" /old_locus_tag="BSU14820" promotor_-10 complement(1551294..1551313) /Source="Nicolas_upshift_promotors" /id="U1232" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.921078921078921" /psig="0.987012987012987" /xcortree=2208 /SigmaFactorBS="aaacaccctcgttccctcagcatttcaatacacataatttgt acacaAAGTGACAattcatgcgaaaacTTTTATAATTTTGAGAGAAGggggtcatatc a" /listShort="ylaL, S539" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1551322) /Source="Nicolas_upshifts" /id="U1232" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.921078921078921" /psig="0.987012987012987" /xcortree=2208 /SigmaFactorBS="aaacaccctcgttccctcagcatttcaatacacataatttgt acacaAAGTGACAattcatgcgaaaacTTTTATAATTTTGAGAGAAGggggtcatatc a" /listShort="ylaL, S539" /GFF_Attribute="listLong" promotor_-35 complement(1551328..1551335) /Source="Nicolas_upshift_promotors" /id="U1232" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.921078921078921" /psig="0.987012987012987" /xcortree=2208 /SigmaFactorBS="aaacaccctcgttccctcagcatttcaatacacataatttgt acacaAAGTGACAattcatgcgaaaacTTTTATAATTTTGAGAGAAGggggtcatatc a" /listShort="ylaL, S539" /GFF_Attribute="listLong" /label="promotor_-35" CDS 1551385..1552314 /gene="glsB" /locus_tag="BSU_14830" /old_locus_tag="BSU14830" /EC_number="3.5.1.2" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:18459799" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 18459799; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="L-glutamine amidohydrolase; glutaminase" /protein_id="NP_389366.1" /db_xref="EnsemblGenomes-Gn:BSU14830" /db_xref="EnsemblGenomes-Tr:CAB13356" /db_xref="GOA:O07637" /db_xref="InterPro:IPR012338" /db_xref="InterPro:IPR015868" /db_xref="SubtiList:BG13350" /db_xref="UniProtKB/Swiss-Prot:O07637" /translation="MVCQHNDELEALVKKAKKVTDKGEVASYIPALAKADKHDLSVAI YYSNNVCLSAGDVEKTFTLQSISKVLSLALVLMEYGKDKVFSYVGQEPTGDPFNSIIK LETVNPSKPLNPMINAGALVVTSLIRGRTVKERLDYLLSFIRRLTNNQEITYCREVAE SEYSTSMINRAMCYYMKQYGIFEDDVEAVMDLYTKQCAIEMNSLDLAKIGSVFALNGR HPETGEQVISKDVARICKTFMVTCGMYNASGEFAIKVGIPAKSGVSGGIMGISPYDFG IGIFGPALDEKGNSIAGVKLLEIMSEMYRLSIF*" gene 1551385..1552314 /gene="glsB" /locus_tag="BSU_14830" /old_locus_tag="BSU14830" misc_feature 1551899..1551918 /Source="Nicolas_upshift_promotors" /id="U1233" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.9000999000999" /psig="0.99100899100899" /xcortree=596 /SigmaFactorBS="gccgggaagtggctgaatctgaatacagcacttcaatgatta atcgggcgaTGTGTTATTATATGAAGCAGtacggcatttttgaagatgatgtagaggc a" /GFF_Attribute="listShort" /listLong="ylaN" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 1551908 /Source="Nicolas_upshifts" /id="U1233" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.9000999000999" /psig="0.99100899100899" /xcortree=596 /SigmaFactorBS="gccgggaagtggctgaatctgaatacagcacttcaatgatta atcgggcgaTGTGTTATTATATGAAGCAGtacggcatttttgaagatgatgtagaggc a" /GFF_Attribute="listShort" /listLong="ylaN" promotor_-35 1552338..1552341 /Source="Nicolas_upshift_promotors" /id="U1234" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.672327672327672" /psig=1 /xcortree=413 /SigmaFactorBS="gtattttttaatttatgtcatatgcttaaatcctCTTGcatt ttctgttgatACCCTTTATGATAAATAGAAgaattaggtactcgcctggggaacggag g" /listShort="ylaN, S541, ftsW, pycA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1552356..1552375 /Source="Nicolas_upshift_promotors" /id="U1234" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.672327672327672" /psig=1 /xcortree=413 /SigmaFactorBS="gtattttttaatttatgtcatatgcttaaatcctCTTGcatt ttctgttgatACCCTTTATGATAAATAGAAgaattaggtactcgcctggggaacggag g" /listShort="ylaN, S541, ftsW, pycA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1552364 /Source="Nicolas_upshifts" /id="U1234" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.672327672327672" /psig=1 /xcortree=413 /SigmaFactorBS="gtattttttaatttatgtcatatgcttaaatcctCTTGcatt ttctgttgatACCCTTTATGATAAATAGAAgaattaggtactcgcctggggaacggag g" /listShort="ylaN, S541, ftsW, pycA" /GFF_Attribute="listLong" CDS 1552412..1552693 /gene="ylaN" /locus_tag="BSU_14840" /old_locus_tag="BSU14840" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 12682299, 16880555, 17005971,17469204" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_389367.1" /db_xref="EnsemblGenomes-Gn:BSU14840" /db_xref="EnsemblGenomes-Tr:CAB13357" /db_xref="InterPro:IPR009983" /db_xref="InterPro:IPR036270" /db_xref="SubtiList:BG13351" /db_xref="UniProtKB/Swiss-Prot:O07638" /translation="MASEMIVDHRQKAFELLKVDAEKILKLIRVQMDNLTMPQCPLYE EVLDTQMFGLSREIDFAVRLGLVDEKDGKDLLYTLERELSALHDAFTAK*" gene 1552412..1552693 /gene="ylaN" /locus_tag="BSU_14840" /old_locus_tag="BSU14840" downshifts 1552682 /Source="Nicolas_upshifts" /id="D838" /incds=0 /nref=72 /ntot=227 /MaxReadThrough="5.3857" /MaxDrop="6.58793" /score="2.26145837" /energy="-6.9" /TU="U1234" /idTUdmin="U1231" /TUdmin=328 /isTUend="FALSE" promotor_-35 1552756..1552759 /Source="Nicolas_upshift_promotors" /id="U1235" /multdbtbs="-" /comp="M2" /sig="SigI" /pcomp="0.619380619380619" /psig="0.619380619380619" /xcortree=1767 /SigmaFactorBS="attaacagtttgggtttttttataaccgctatttttctctca tcTCATaaaagacggtcttttttTACACATtccttccgaatcgtatagagattcttcg t" /listShort="S541, ftsW, pycA" /GFF_Attribute="listLong" /label="promotor_-35" S_feature 1552772..1552898 /Source="Nicolas_S_feature" /locus_tag="new_1552772_1552898" /HighExp="S1, T5.0H, T4.0H, HiOs, T3.30H, T3.0H, Etha, Heat, T2.0H, S2" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigI, SigA" /TUshortPSig="0.619, 1" /TUlongSig="SigEF" /TUlongPSig="0.999" /label="S541" upshifts 1552772 /Source="Nicolas_upshifts" /id="U1235" /multdbtbs="-" /comp="M2" /sig="SigI" /pcomp="0.619380619380619" /psig="0.619380619380619" /xcortree=1767 /SigmaFactorBS="attaacagtttgggtttttttataaccgctatttttctctca tcTCATaaaagacggtcttttttTACACATtccttccgaatcgtatagagattcttcg t" /listShort="S541, ftsW, pycA" /GFF_Attribute="listLong" promotor_-10 1552777..1552783 /Source="Nicolas_upshift_promotors" /id="U1235" /multdbtbs="-" /comp="M2" /sig="SigI" /pcomp="0.619380619380619" /psig="0.619380619380619" /xcortree=1767 /SigmaFactorBS="attaacagtttgggtttttttataaccgctatttttctctca tcTCATaaaagacggtcttttttTACACATtccttccgaatcgtatagagattcttcg t" /listShort="S541, ftsW, pycA" /GFF_Attribute="listLong" /label="promotor_-10" CDS 1552899..1554110 /gene="ftsW" /locus_tag="BSU_14850" /old_locus_tag="BSU14850" /function="16.13: Shape" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:9622350, 12626683, 15849754, 16850406, 21386816, 27895631" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9622350, 12626683, 15849754, 16850406, 21386816, 27895631; Product type t : transporter" /codon_start=1 /transl_table=11 /product="cell-division protein; transporter of lipid-linked cell wall precursors" /protein_id="NP_389368.1" /db_xref="EnsemblGenomes-Gn:BSU14850" /db_xref="EnsemblGenomes-Tr:CAB13358" /db_xref="GOA:O07639" /db_xref="InterPro:IPR001182" /db_xref="InterPro:IPR018365" /db_xref="SubtiList:BG13352" /db_xref="UniProtKB/Swiss-Prot:O07639" /translation="MLKKMLKSYDYSLIFAIVLLCGFGLVMVYSSSMITAVSRYGVSS NFFFMRQLFALIAGGALFILMALFPYKALAHQKFQKGILLVSVLALISLFVFGHVAGN AQSWFKIGGMSIQPGEFVKLVVILYLAAVYAKKQSYIDHLLTGVAPPVVMTLIICGLI AMQPDFGTAMIIGLIATCMILCSGFSGKTLVRLVILGGIVFILVSPIIYLNQDKILTE GRLARFESLEDPFKYANSSGLQVINSYYAISSGGIFGLGLGESIQKYGYLPESHTDFI MAVIAEELGIFGVLFVIFLLGFVVIKGFYIARKCEDPFGSLLAIGISSMIAIQSFINL GGVSGLIPITGVTLPFISYGGSSLVLLLGSMGILANISMFVKYSENKKKKEPLAPKGM KKKQLKKTVYL*" gene 1552899..1554110 /gene="ftsW" /locus_tag="BSU_14850" /old_locus_tag="BSU14850" promotor_-35 1554120..1554124 /Source="Nicolas_upshift_promotors" /id="U1236" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.320679320679321" /psig="0.98901098901099" /xcortree=2763 /SigmaFactorBS="tgtttatctgtaaaaaacaagtGTGTAcaggggaaggatatT CCGCTATGATAGATTATATtccattcgggtaagggggagaaaagtttgtctcagcaat c" /listShort="pycA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1554139..1554158 /Source="Nicolas_upshift_promotors" /id="U1236" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.320679320679321" /psig="0.98901098901099" /xcortree=2763 /SigmaFactorBS="tgtttatctgtaaaaaacaagtGTGTAcaggggaaggatatT CCGCTATGATAGATTATATtccattcgggtaagggggagaaaagtttgtctcagcaat c" /listShort="pycA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1554158 /Source="Nicolas_upshifts" /id="U1236" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.320679320679321" /psig="0.98901098901099" /xcortree=2763 /SigmaFactorBS="tgtttatctgtaaaaaacaagtGTGTAcaggggaaggatatT CCGCTATGATAGATTATATtccattcgggtaagggggagaaaagtttgtctcagcaat c" /listShort="pycA" /GFF_Attribute="listLong" CDS 1554185..1557631 /gene="pycA" /locus_tag="BSU_14860" /old_locus_tag="BSU14860" /EC_number="6.4.1.1" /function="16.2: Construct biomass (Anabolism)" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 6425269, 15134465, 20081037, 20097852; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="pyruvate carboxylase" /protein_id="NP_389369.1" /db_xref="EnsemblGenomes-Gn:BSU14860" /db_xref="EnsemblGenomes-Tr:CAB13359" /db_xref="GOA:Q9KWU4" /db_xref="InterPro:IPR000089" /db_xref="InterPro:IPR000891" /db_xref="InterPro:IPR003379" /db_xref="InterPro:IPR005479" /db_xref="InterPro:IPR005481" /db_xref="InterPro:IPR005482" /db_xref="InterPro:IPR005930" /db_xref="InterPro:IPR011053" /db_xref="InterPro:IPR011054" /db_xref="InterPro:IPR011761" /db_xref="InterPro:IPR011764" /db_xref="InterPro:IPR013785" /db_xref="InterPro:IPR013815" /db_xref="InterPro:IPR016185" /db_xref="SubtiList:BG12660" /db_xref="UniProtKB/Swiss-Prot:Q9KWU4" /translation="MSQQSIQKVLVANRGEIAIRIFRACTELNIRTVAVYSKEDSGSY HRYKADEAYLVGEGKKPIDAYLDIEGIIDIAKRNKVDAIHPGYGFLSENIHFARRCEE EGIVFIGPKSEHLDMFGDKVKAREQAEKAGIPVIPGSDGPAETLEAVEQFGQANGYPI IIKASLGGGGRGMRIVRSESEVKEAYERAKSEAKAAFGNDEVYVEKLIENPKHIEVQV IGDKQGNVVHLFERDCSVQRRHQKVIEVAPSVSLSPELRDQICEAAVALAKNVNYINA GTVEFLVANNEFYFIEVNPRVQVEHTITEMITGVDIVQTQILVAQGHSLHSKKVNIPE QKDIFTIGYAIQSRVTTEDPQNDFMPDTGKIMAYRSGGGFGVRLDTGNSFQGAVITPY YDSLLVKLSTWALTFEQAAAKMVRNLQEFRIRGIKTNIPFLENVAKHEKFLTGQYDTS FIDTTPELFNFPKQKDRGTKMLTYIGNVTVNGFPGIGKKEKPAFDKPLGVKVDVDQQP ARGTKQILDEKGAEGLANWVKEQKSVLLTDTTFRDAHQSLLATRIRSHDLKKIANPTA ALWPELFSMEMWGGATFDVAYRFLKEDPWKRLEDLRKEVPNTLFQMLLRSSNAVGYTN YPDNVIKEFVKQSAQSGIDVFRIFDSLNWVKGMTLAIDAVRDTGKVAEAAICYTGDIL DKNRTKYDLAYYTSMAKELEAAGAHILGIKDMAGLLKPQAAYELVSALKETIDIPVHL HTHDTSGNGIYMYAKAVEAGVDIIDVAVSSMAGLTSQPSASGFYHAMEGNDRRPEMNV QGVELLSQYWESVRKYYSEFESGMKSPHTEIYEHEMPGGQYSNLQQQAKGVGLGDRWN EVKEMYRRVNDMFGDIVKVTPSSKVVGDMALYMVQNNLTEKDVYEKGESLDFPDSVVE LFKGNIGQPHGGFPEKLQKLILKGQEPITVRPGELLEPVSFEAIKQEFKEQHNLEISD QDAVAYALYPKVFTDYVKTTESYGDISVLDTPTFFYGMTLGEEIEVEIERGKTLIVKL ISIGEPQPDATRVVYFELNGQPREVVIKDESIKSSVQERLKADRTNPSHIAASMPGTV IKVLAEAGTKVNKGDHLMINEAMKMETTVQAPFSGTIKQVHVKNGEPIQTGDLLLEIE KA*" gene 1554185..1557631 /gene="pycA" /locus_tag="BSU_14860" /old_locus_tag="BSU14860" promotor_-10 complement(1557197..1557215) /Source="Nicolas_upshift_promotors" /id="U1237" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.98901098901099" /psig="0.98901098901099" /xcortree=1065 /SigmaFactorBS="aatcagcttaacgatcagcgttttgccgcgctcaatttcaaC TTCTAtctcttcacctaatgTCATACCGTAGAAGAATGTcggtgtatctaataccgag a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1557217) /Source="Nicolas_upshifts" /id="U1237" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.98901098901099" /psig="0.98901098901099" /xcortree=1065 /SigmaFactorBS="aatcagcttaacgatcagcgttttgccgcgctcaatttcaaC TTCTAtctcttcacctaatgTCATACCGTAGAAGAATGTcggtgtatctaataccgag a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(1557231..1557236) /Source="Nicolas_upshift_promotors" /id="U1237" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.98901098901099" /psig="0.98901098901099" /xcortree=1065 /SigmaFactorBS="aatcagcttaacgatcagcgttttgccgcgctcaatttcaaC TTCTAtctcttcacctaatgTCATACCGTAGAAGAATGTcggtgtatctaataccgag a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 1557611 /Source="Nicolas_upshifts" /id="D839" /incds=0 /nref=20 /ntot=213 /MaxReadThrough="5.5667" /MaxDrop="6.03063" /score="0.893081758" /energy="-11.8" /TU="U1236" /idTUdmin="U1234" /TUdmin="-1" /isTUend="TRUE" downshifts 1557656 /Source="Nicolas_upshifts" /id="D840" /incds=0 /nref=2 /ntot=51 /MaxReadThrough="4.21552" /MaxDrop="4.9051" /score="0.893081758" /energy="-11.8" /TU="U1236" /idTUdmin="U1234" /TUdmin=44 /isTUend="FALSE" downshifts complement(1557688) /Source="Nicolas_upshifts" /id="D841" /incds=0 /nref=2 /ntot=10 /MaxReadThrough="2.24992" /MaxDrop="3.11732" /score="10.1921506" /energy="-11.8" /TU="NA" /idTUdmin="U1238" /TUdmin=330 /isTUend="FALSE" downshifts 1557700 /Source="Nicolas_upshifts" /id="D842" /incds=0 /nref=1 /ntot=2 /MaxReadThrough="3.6246" /MaxDrop="4.10361" /score="0.893081758" /energy="-11.8" /TU="U1236" /idTUdmin="U1234" /TUdmin=88 /isTUend="FALSE" CDS complement(1558034..1558954) /gene="ctaA" /locus_tag="BSU_14870" /old_locus_tag="BSU14870" /EC_number="1.3.-.-" /function="16.10: Respire" /experiment="publication(s) with functional evidences, PMID:12206660, 15491161, 15849754, 16321940, 16850406, 26592143" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12206660, 15491161, 15849754, 16321940, 16850406, 26592143; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="heme-A synthase" /protein_id="NP_389370.1" /db_xref="EnsemblGenomes-Gn:BSU14870" /db_xref="EnsemblGenomes-Tr:CAB13360" /db_xref="GOA:P12946" /db_xref="InterPro:IPR003780" /db_xref="InterPro:IPR023755" /db_xref="SubtiList:BG10213" /db_xref="UniProtKB/Swiss-Prot:P12946" /translation="MNKALKALGVLTTFVMLIVLIGGALVTKTGSGQGCGRQWPLCHG RFFPELNPASIIEWSHRFASGISIILVLSLAFWSWRKITPIFRETTFLAIMSIIFLFL QALLGALAVVFGSNALIMALHFGISLISFASVLILTLLIFEADKSVRTLVKPLQIGKK MQFHMIGILIYSYIVVYTGAYVRHTESSLACPNVPLCSPLNNGLPTQFHEWVQMGHRA AALLLFVWIIVAAVHAITSYKDQKQIFWGWISCLIFITLQALSGIMIVYSELALGFAL AHSFFIACLFGVLCYFLLLIARFRYESRQS*" gene complement(1558034..1558954) /gene="ctaA" /locus_tag="BSU_14870" /old_locus_tag="BSU14870" downshifts complement(1558040) /Source="Nicolas_upshifts" /id="D843" /incds=0 /nref=126 /ntot=238 /MaxReadThrough="2.72676" /MaxDrop="5.67271" /score="28.8671863" /energy="-15.3" /TU="U1238" /idTUdmin="U1238" /TUdmin="-22" /isTUend="TRUE" promotor_-10 complement(1558994..1559013) /Source="Nicolas_upshift_promotors" /id="U1238" /multdbtbs="SigA,SigE" /comp="M19" /sig="SigA" /pcomp="0.833166833166833" /psig=1 /xcortree=1626 /SigmaFactorBS="cattctattatatttttgtgaacaaaaggctctggGAATTGC CacaaaacacatatTCGCTTACACTTGGAACGTAtataaaattgcagcagtatgttaa g" /listShort="ctaA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1559009) /Source="Nicolas_upshifts" /id="U1238" /multdbtbs="SigA,SigE" /comp="M19" /sig="SigA" /pcomp="0.833166833166833" /psig=1 /xcortree=1626 /SigmaFactorBS="cattctattatatttttgtgaacaaaaggctctggGAATTGC CacaaaacacatatTCGCTTACACTTGGAACGTAtataaaattgcagcagtatgttaa g" /listShort="ctaA" /GFF_Attribute="listLong" promotor_-35 complement(1559027..1559034) /Source="Nicolas_upshift_promotors" /id="U1238" /multdbtbs="SigA,SigE" /comp="M19" /sig="SigA" /pcomp="0.833166833166833" /psig=1 /xcortree=1626 /SigmaFactorBS="cattctattatatttttgtgaacaaaaggctctggGAATTGC CacaaaacacatatTCGCTTACACTTGGAACGTAtataaaattgcagcagtatgttaa g" /listShort="ctaA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1559089..1559096 /Source="Nicolas_upshift_promotors" /id="U1239" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.824175824175824" /psig=1 /xcortree=1603 /SigmaFactorBS="acaaaaatataatagaatgacggcttctggaaaatgtaCACT TGATtattcatgccgggTCTGATAGAAATAAGGTAAAcgcaatgccgatttggagatt g" /listShort="S542, S543, ctaB, S544, ctaC, ctaD, ctaE, ctaF, ctaG" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1559110..1559129 /Source="Nicolas_upshift_promotors" /id="U1239" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.824175824175824" /psig=1 /xcortree=1603 /SigmaFactorBS="acaaaaatataatagaatgacggcttctggaaaatgtaCACT TGATtattcatgccgggTCTGATAGAAATAAGGTAAAcgcaatgccgatttggagatt g" /listShort="S542, S543, ctaB, S544, ctaC, ctaD, ctaE, ctaF, ctaG" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 1559111..1559216 /Source="Nicolas_S_feature" /locus_tag="new_1559111_1559216" /HighExp="LBGstat, M0t90, Lbstat, BC, T0.30H, T1.30H, B60, M9-stat, M40t90, S2" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S542" upshifts 1559111 /Source="Nicolas_upshifts" /id="U1239" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.824175824175824" /psig=1 /xcortree=1603 /SigmaFactorBS="acaaaaatataatagaatgacggcttctggaaaatgtaCACT TGATtattcatgccgggTCTGATAGAAATAAGGTAAAcgcaatgccgatttggagatt g" /listShort="S542, S543, ctaB, S544, ctaC, ctaD, ctaE, ctaF, ctaG" /GFF_Attribute="listLong" S_feature 1559218..1559308 /Source="Nicolas_S_feature" /locus_tag="new_1559218_1559308" /HighExp="LBGstat, M0t90, LPhT, BC, UNK1, BI, Lbexp, LBGtran, Lbstat, ferm" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="0.994, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S543" upshifts 1559218 /Source="Nicolas_upshifts" /id="U1240" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.977022977022977" /psig="0.994005994005994" /xcortree=2711 /SigmaFactorBS="tctttggtaaaattcataaaaagttcacaaataaattcctgt ttgtcgtttaatatttaataggatGTTTttttacaagatgttATCTTGTATGATAGAG T" /listShort="S543, ctaB, S544, ctaC, ctaD, ctaE, ctaF, ctaG" /GFF_Attribute="listLong" promotor_-35 1559224..1559227 /Source="Nicolas_upshift_promotors" /id="U1240" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.977022977022977" /psig="0.994005994005994" /xcortree=2711 /SigmaFactorBS="tctttggtaaaattcataaaaagttcacaaataaattcctgt ttgtcgtttaatatttaataggatGTTTttttacaagatgttATCTTGTATGATAGAG T" /listShort="S543, ctaB, S544, ctaC, ctaD, ctaE, ctaF, ctaG" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1559242..1559258 /Source="Nicolas_upshift_promotors" /id="U1240" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.977022977022977" /psig="0.994005994005994" /xcortree=2711 /SigmaFactorBS="tctttggtaaaattcataaaaagttcacaaataaattcctgt ttgtcgtttaatatttaataggatGTTTttttacaagatgttATCTTGTATGATAGAG T" /listShort="S543, ctaB, S544, ctaC, ctaD, ctaE, ctaF, ctaG" /GFF_Attribute="listLong" /label="promotor_-10" CDS 1559309..1560226 /gene="ctaB" /locus_tag="BSU_14880" /old_locus_tag="BSU14880" /EC_number="2.5.1.-" /function="16.10: Respire" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:8082800, 10675592, 15849754, 16850406, 7968515, 9829923, 19204012" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8082800, 10675592, 15849754, 16850406, 7968515, 9829923, 19204012; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="protoheme IX farnesyltransferase 2" /protein_id="NP_389371.1" /db_xref="EnsemblGenomes-Gn:BSU14880" /db_xref="EnsemblGenomes-Tr:CAB13361" /db_xref="GOA:P24009" /db_xref="InterPro:IPR000537" /db_xref="InterPro:IPR006369" /db_xref="InterPro:IPR030470" /db_xref="SubtiList:BG10214" /db_xref="UniProtKB/Swiss-Prot:P24009" /translation="MANSRILNDTAIDGQIEETTAWKDFLSLIKIGIVNSNLITTFTG MWLALHISGLSFLGNINTVLLTLIGSSLIIAGSCAINNWYDRDIDHLMERTKVRPTVT GKIQPSQALWSGILLVALGLIMLLMTTVMAAVIGFIGVFTYVVLYTMWTKRRYTINTV VGSVSGAVPPLIGWTAVEGNIGVVAWVLFMILFIWQIPHFLALAIKKTEDYRAANIPM LPVVYGFEVTKRQIIVWVACLMPLPFFLGSLGLPIVILGLLLNIGWLILGLMGFRSKN IMKWATQMFVYSLNYMTIYFVAMVVLTLF*" gene 1559309..1560226 /gene="ctaB" /locus_tag="BSU_14880" /old_locus_tag="BSU14880" downshifts 1560255 /Source="Nicolas_upshifts" /id="D844" /incds=0 /nref=33 /ntot=75 /MaxReadThrough="8.35391" /MaxDrop="5.6457" /score="0.893081758" /energy="-11.8" /TU="U1239,U1240" /idTUdmin="U1236" /TUdmin=1719 /isTUend="FALSE" upshifts 1560274 /Source="Nicolas_upshifts" /id="U1241" /multdbtbs="-" /comp="M2" /sig="Sig-" /pcomp="0.406593406593407" /psig="0.406593406593407" /xcortree=510 /SigmaFactorBS="gacgcttttctaaaaaatagatatgatgcttgttttatcgct tcaaaataaacgatgacaaCTAGTAaatgccgccttgacctcttgtttaatcaggcgg c" /listShort="S544, ctaC, ctaD, ctaE, ctaF, ctaG" /GFF_Attribute="listLong" misc_feature 1560275..1560280 /Source="Nicolas_upshift_promotors" /id="U1241" /multdbtbs="-" /comp="M2" /sig="Sig-" /pcomp="0.406593406593407" /psig="0.406593406593407" /xcortree=510 /SigmaFactorBS="gacgcttttctaaaaaatagatatgatgcttgttttatcgct tcaaaataaacgatgacaaCTAGTAaatgccgccttgacctcttgtttaatcaggcgg c" /listShort="S544, ctaC, ctaD, ctaE, ctaF, ctaG" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" promotor_-35 1560334..1560339 /Source="Nicolas_upshift_promotors" /id="U1242" /multdbtbs="-" /comp="M3" /sig="Sig-" /pcomp="0.450549450549451" /psig="0.450549450549451" /xcortree=338 /SigmaFactorBS="ttaatcaggcggctttacttttatacatagatGGCATTttga gtaaaaaaacTCATAATTTAAGAGAAGAGgaaatgtaagtgctttattggtgataggt t" /listShort="S544, ctaC, ctaD, ctaE, ctaF, ctaG" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1560354..1560372 /Source="Nicolas_upshift_promotors" /id="U1242" /multdbtbs="-" /comp="M3" /sig="Sig-" /pcomp="0.450549450549451" /psig="0.450549450549451" /xcortree=338 /SigmaFactorBS="ttaatcaggcggctttacttttatacatagatGGCATTttga gtaaaaaaacTCATAATTTAAGAGAAGAGgaaatgtaagtgctttattggtgataggt t" /listShort="S544, ctaC, ctaD, ctaE, ctaF, ctaG" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 1560362..1560465 /Source="Nicolas_S_feature" /locus_tag="new_1560362_1560465" /HighExp="Lbstat, M0t90, M40t90, T2.30H, T3.30H, T2.0H, T3.0H, T4.0H, T1.30H, S2" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="Sig-, Sig-, SigA, SigA" /TUshortPSig="0.451, 0.407, 0.994, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S544" upshifts 1560362 /Source="Nicolas_upshifts" /id="U1242" /multdbtbs="-" /comp="M3" /sig="Sig-" /pcomp="0.450549450549451" /psig="0.450549450549451" /xcortree=338 /SigmaFactorBS="ttaatcaggcggctttacttttatacatagatGGCATTttga gtaaaaaaacTCATAATTTAAGAGAAGAGgaaatgtaagtgctttattggtgataggt t" /listShort="S544, ctaC, ctaD, ctaE, ctaF, ctaG" /GFF_Attribute="listLong" CDS 1560466..1561536 /gene="ctaC" /locus_tag="BSU_14890" /old_locus_tag="BSU14890" /EC_number="1.9.3.1" /function="16.10: Respire" /experiment="publication(s) with functional evidences, PMID:1685007, 1847686, 9829923, 9882689, 27503613" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1685007, 1847686, 9829923, 9882689, 27503613; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="cytochrome caa3 oxidase (subunit II)" /protein_id="NP_389372.1" /db_xref="EnsemblGenomes-Gn:BSU14890" /db_xref="EnsemblGenomes-Tr:CAB13362" /db_xref="GOA:P24011" /db_xref="InterPro:IPR001505" /db_xref="InterPro:IPR002429" /db_xref="InterPro:IPR008972" /db_xref="InterPro:IPR009056" /db_xref="InterPro:IPR011759" /db_xref="InterPro:IPR014222" /db_xref="InterPro:IPR034236" /db_xref="InterPro:IPR036257" /db_xref="InterPro:IPR036909" /db_xref="SubtiList:BG10215" /db_xref="UniProtKB/Swiss-Prot:P24011" /translation="MVKHWRLILLLALVPLLLSGCGKPFLSTLKPAGEVADKQYDLTV LSTLIMVVVVAVVSVIFFYVIVRFRRSRVGENTIPKQVEGNKFLEITWTVIPILLLII LVIPVVLYTLELADTSPMDKKGRKAEDALVVNVRANLYWWEFEYPDYGIITSQELIVP TDQRVYFNLKASDVKHSFWIPSVGGKLDTNTDNENKFFLTFDSKRSKEAGDMFFGKCA ELCGPSHALMDFKVKTMSAKEFQGWTKEMKNYKSTAESDLAKQGEELFKEKNCLSCHA VEPNDKRAEAARTAPNLATFGERTKVAGVKEANKENVKAWLKDPDSIKPGNKMTGTYP KLSDSETNALYEYLKGLKAESK*" gene 1560466..1561536 /gene="ctaC" /locus_tag="BSU_14890" /old_locus_tag="BSU14890" CDS 1561569..1563437 /gene="ctaD" /locus_tag="BSU_14900" /old_locus_tag="BSU14900" /EC_number="1.9.3.1" /function="16.10: Respire" /experiment="publication(s) with functional evidences, PMID:1685007, 1847686, 10675592, 15849754, 16850406, 27503613" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1685007, 1847686, 10675592, 15849754, 16850406, 27503613; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="cytochrome caa3 oxidase (subunit I)" /protein_id="NP_389373.2" /db_xref="EnsemblGenomes-Gn:BSU14900" /db_xref="EnsemblGenomes-Tr:CAB13363" /db_xref="GOA:P24010" /db_xref="InterPro:IPR000883" /db_xref="InterPro:IPR014241" /db_xref="InterPro:IPR023615" /db_xref="InterPro:IPR023616" /db_xref="InterPro:IPR036927" /db_xref="SubtiList:BG10216" /db_xref="UniProtKB/Swiss-Prot:P24010" /translation="MLNALTEKRTRGSMLWDYLTTVDHKKIAILYLVAGGFFFLVGGI EAMFIRIQLAKPENAFLSAQAYNEVMTMHGTTMIFLAAMPLLFALMNAVVPLQIGARD VSFPFLNALGFWLFFFGGIFLNLSWFLGGAPDAGWTSYASLSLHSKGHGIDFFVLGLQ ISGLGTLIAGINFLATIINMRAPGMTYMRLPLFTWTTFVASALILFAFPPLTVGLALM MLDRLFGTNFFNPELGGNTVIWEHLFWIFGHPEVYILILPAFGIFSEVIPVFARKRLF GYSSMVFAIVLIGFLGFMVWVHHMFTTGLGPIANAIFAVATMAIAIPTGIKIFNWLLT IWGGNVKYTTAMLYAVSFIPSFVLGGVTGVMLAAAAADYQFHDTYFVVAHFHYVIIGG VVFGLLAGVHFWWPKMFGKILHETMGKISFVLFFIGFHLTFFIQHFVGLMGMPRRVYT FLPGQGLETGNLISTIGAFFMAAAVILLLVNVIWTSVKGEYVGADPWHDGRTLEWTVS SPPPEYNFKQLPFVRGLDPLWIEKQAGHKSMTPAEPVDDIHMPNGSILPLIISFGLFV AAFGLLYRSDYAWGLPVIFIGLGITFITMLLRSVIDDHGYHIHKEELPNDDKGVKA*" gene 1561569..1563437 /gene="ctaD" /locus_tag="BSU_14900" /old_locus_tag="BSU14900" CDS 1563437..1564060 /gene="ctaE" /locus_tag="BSU_14910" /old_locus_tag="BSU14910" /EC_number="1.9.3.1" /function="16.10: Respire" /experiment="publication(s) with functional evidences, PMID:1685007, 1847686, 10675592, 15849754, 16850406, 27503613" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1685007, 1847686, 10675592, 15849754, 16850406, 27503613; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="cytochrome caa3 oxidase (subunit III)" /protein_id="NP_389374.1" /db_xref="EnsemblGenomes-Gn:BSU14910" /db_xref="EnsemblGenomes-Tr:CAB13364" /db_xref="GOA:P24012" /db_xref="InterPro:IPR000298" /db_xref="InterPro:IPR013833" /db_xref="InterPro:IPR024791" /db_xref="InterPro:IPR033946" /db_xref="InterPro:IPR035973" /db_xref="SubtiList:BG10217" /db_xref="UniProtKB/Swiss-Prot:P24012" /translation="MQVQEKFTAETFPASPEKVTLEGKNKFLGFWLFLGGETVLFASL FATFLALRNSNAGDPPTTEMFDVTLVFIATMLLLTSSLTSVYAMYHMKNFSFGKMQLW LGITILLGAGFLGLEIYEFKHYTHEFGFTITSSALGSAFYTLVGTHGAHVAFGLMWIS TLMIRNAKRGLNLYTAPKFYVASLYWHFIDVVWVFIFTVVYLMGMVG*" gene 1563437..1564060 /gene="ctaE" /locus_tag="BSU_14910" /old_locus_tag="BSU14910" CDS 1564063..1564395 /gene="ctaF" /locus_tag="BSU_14920" /old_locus_tag="BSU14920" /EC_number="1.9.3.1" /function="16.10: Respire" /experiment="publication(s) with functional evidences, PMID:1685007, 1847686, 10675592, 15849754, 16850406, 27503613" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1685007, 1847686, 10675592, 15849754, 16850406, 27503613; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="cytochrome caa3 oxidase (subunit IV)" /protein_id="NP_389375.1" /db_xref="EnsemblGenomes-Gn:BSU14920" /db_xref="EnsemblGenomes-Tr:CAB13365" /db_xref="GOA:P24013" /db_xref="InterPro:IPR005171" /db_xref="InterPro:IPR014257" /db_xref="SubtiList:BG10218" /db_xref="UniProtKB/Swiss-Prot:P24013" /translation="MVDKKSRGHINSDLEFKKKKHAREMKYQVLSFGLMIGLTIVAFL TVATDGVGSWFTIPFIILLAAIQVIFQLYYFMHMNQKGHEAPALFLYSGVFVAFITVL AFVTIIWW*" gene 1564063..1564395 /gene="ctaF" /locus_tag="BSU_14920" /old_locus_tag="BSU14920" CDS 1564422..1565315 /gene="ctaG" /locus_tag="BSU_14930" /old_locus_tag="BSU14930" /function="16.10: Respire" /function="16.13: Shape" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:14766920, 15849754, 16305244, 16850406" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 14766920, 15849754, 16305244, 16850406; Product type f: factor" /codon_start=1 /transl_table=11 /product="cytochrome aa(3) assembly factor" /protein_id="NP_389376.1" /db_xref="EnsemblGenomes-Gn:BSU14930" /db_xref="EnsemblGenomes-Tr:CAB13366" /db_xref="GOA:O34329" /db_xref="InterPro:IPR014108" /db_xref="InterPro:IPR019108" /db_xref="SubtiList:BG12579" /db_xref="UniProtKB/Swiss-Prot:O34329" /translation="MNQLEIFGFRAMWSPYLFCILLGITALYLYFYRRMSSKPNRITG KEMVCFLSAMLFLYAAEGSPVDLLGHIMFSAHMVQMAVLYLVVPPLLIAGIPAWLWEK IIFRPSIKPVFSFFTTPLIALLLFNGIFSLYHVPLIFDTVKTDPFYHTLITWLIFVLA FFMWWPLVHKVERLRQLSGLMKLGYIMADGMLLTPACALIMFSGAPLYATYTDPALWA EAMRLCVPADMMGQVPLTGPEMLNTLPLLEDQQLGAVMMKIIQEIVYGTFLAVIFFQW VKKEREKDGQEEPPYIQQTIS*" gene 1564422..1565315 /gene="ctaG" /locus_tag="BSU_14930" /old_locus_tag="BSU14930" downshifts 1565290 /Source="Nicolas_upshifts" /id="D845" /incds=0 /nref=121 /ntot=229 /MaxReadThrough="1.94099" /MaxDrop="5.91271" /score="4.35633365" /energy="-13.3" /TU="NA" /idTUdmin="U1239" /TUdmin=0 /isTUend="TRUE" CDS complement(1565347..1565709) /gene="ylbA" /locus_tag="BSU_14940" /old_locus_tag="BSU14940" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_389377.1" /db_xref="EnsemblGenomes-Gn:BSU14940" /db_xref="EnsemblGenomes-Tr:CAB13367" /db_xref="InterPro:IPR014967" /db_xref="InterPro:IPR036491" /db_xref="SubtiList:BG13353" /db_xref="UniProtKB/Swiss-Prot:O34743" /translation="MLKFTESGLEGVKAELSWLDDLMESKGLIRAGQWDYERVTYDKK FSTIEGTFYLRIQGIAAEGDVGSGRAVIQLMSPLLGKHYYPHGVEYGETEEFPVQVVT KSKALIQDIANMLKTVQM*" gene complement(1565347..1565709) /gene="ylbA" /locus_tag="BSU_14940" /old_locus_tag="BSU14940" downshifts complement(1565366) /Source="Nicolas_upshifts" /id="D846" /incds=0 /nref=217 /ntot=257 /MaxReadThrough="1.00586" /MaxDrop="6.68145" /score="-3.42191479" /energy="-11.2" /TU="NA" /idTUdmin="U1244" /TUdmin=0 /isTUend="TRUE" promotor_-35 1565702..1565706 /Source="Nicolas_upshift_promotors" /id="U1243" /multdbtbs="SigF" /comp="M15" /sig="Sig-" /pcomp="0.57942057942058" /psig="0.367632367632368" /xcortree=1041 /SigmaFactorBS="cccttcaagtccgctttcagtaaacTTCAAcactgaccCCTC CTTATAAAAAttacctttcctgacaatcatagtatgaaagcgttaaactttcaatgaa t" /listShort="S545, ylbB, ylbC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1565715..1565728 /Source="Nicolas_upshift_promotors" /id="U1243" /multdbtbs="SigF" /comp="M15" /sig="Sig-" /pcomp="0.57942057942058" /psig="0.367632367632368" /xcortree=1041 /SigmaFactorBS="cccttcaagtccgctttcagtaaacTTCAAcactgaccCCTC CTTATAAAAAttacctttcctgacaatcatagtatgaaagcgttaaactttcaatgaa t" /listShort="S545, ylbB, ylbC" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-10 complement(1565733..1565752) /Source="Nicolas_upshift_promotors" /id="U1244" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.78921078921079" /psig="0.985014985014985" /xcortree=515 /SigmaFactorBS="aatttttgcatactttcaaaagaagaagattCATTGAAAgtt taacgctttcaTACTATGATTGTCAGGAAAGgtaatttttataaggaggggtcagtgt t" /listShort="ylbA" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 1565737..1565848 /Source="Nicolas_S_feature" /locus_tag="new_1565737_1565848" /HighExp="S7, S8, S4, S3, S6, S5, T5.0H, T4.0H, BC, T3.30H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="Sig-" /TUshortPSig="0.368" /TUlongSig="NA" /TUlongPSig="NA" /label="S545" upshifts 1565737 /Source="Nicolas_upshifts" /id="U1243" /multdbtbs="SigF" /comp="M15" /sig="Sig-" /pcomp="0.57942057942058" /psig="0.367632367632368" /xcortree=1041 /SigmaFactorBS="cccttcaagtccgctttcagtaaacTTCAAcactgaccCCTC CTTATAAAAAttacctttcctgacaatcatagtatgaaagcgttaaactttcaatgaa t" /listShort="S545, ylbB, ylbC" /GFF_Attribute="listLong" upshifts complement(1565745) /Source="Nicolas_upshifts" /id="U1244" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.78921078921079" /psig="0.985014985014985" /xcortree=515 /SigmaFactorBS="aatttttgcatactttcaaaagaagaagattCATTGAAAgtt taacgctttcaTACTATGATTGTCAGGAAAGgtaatttttataaggaggggtcagtgt t" /listShort="ylbA" /GFF_Attribute="listLong" promotor_-35 complement(1565767..1565774) /Source="Nicolas_upshift_promotors" /id="U1244" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.78921078921079" /psig="0.985014985014985" /xcortree=515 /SigmaFactorBS="aatttttgcatactttcaaaagaagaagattCATTGAAAgtt taacgctttcaTACTATGATTGTCAGGAAAGgtaatttttataaggaggggtcagtgt t" /listShort="ylbA" /GFF_Attribute="listLong" /label="promotor_-35" CDS 1565849..1566295 /gene="ylbB" /locus_tag="BSU_14950" /old_locus_tag="BSU14950" /EC_number="1.-.-.-" /function="16.11: Scavenge (Catabolism)" /function="18.1: Enzymes of unknown specificity" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative enzyme" /protein_id="NP_389378.2" /db_xref="EnsemblGenomes-Gn:BSU14950" /db_xref="EnsemblGenomes-Tr:CAB13368" /db_xref="InterPro:IPR000644" /db_xref="SubtiList:BG13354" /db_xref="UniProtKB/Swiss-Prot:O34682" /translation="MTKIKDLMTADLQYCTVLDNVYEAAVKMKDANVGAIPVVDEDGE TLVGIVTDRDLVLRGIAIKKPNSQKITDAMTEKPVSVEEDASVDEVLHLMASHQLRRI PVTKNKKLTGIVTLGDLSLSEQTNERAGSALSDISEGDNREEGFFH*" gene 1565849..1566295 /gene="ylbB" /locus_tag="BSU_14950" /old_locus_tag="BSU14950" promotor_-35 1565881..1565888 /Source="Nicolas_upshift_promotors" /id="U1245" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.536463536463537" /psig="0.996003996003996" /xcortree=2165 /SigmaFactorBS="acggatgacaaaaataaaagatctgatgacagccgaCTTGCA ATattgcacggtaTTAGATAATGTATATGAAGCtgcagtaaagatgaaggacgcaaat g" /listShort="ylbC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1565900..1565919 /Source="Nicolas_upshift_promotors" /id="U1245" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.536463536463537" /psig="0.996003996003996" /xcortree=2165 /SigmaFactorBS="acggatgacaaaaataaaagatctgatgacagccgaCTTGCA ATattgcacggtaTTAGATAATGTATATGAAGCtgcagtaaagatgaaggacgcaaat g" /listShort="ylbC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1565905 /Source="Nicolas_upshifts" /id="U1245" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.536463536463537" /psig="0.996003996003996" /xcortree=2165 /SigmaFactorBS="acggatgacaaaaataaaagatctgatgacagccgaCTTGCA ATattgcacggtaTTAGATAATGTATATGAAGCtgcagtaaagatgaaggacgcaaat g" /listShort="ylbC" /GFF_Attribute="listLong" promotor_-35 1566304..1566311 /Source="Nicolas_upshift_promotors" /id="U1246" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.515484515484515" /psig="0.731268731268731" /xcortree=141 /SigmaFactorBS="aagaaggcttttttcattaacacataaaTCTTTGACatgtta aataggcTGTATTGTAATGGGATGTAAacaagagattgtgaatcgccacgggggtgat a" /listShort="ylbC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1566325..1566344 /Source="Nicolas_upshift_promotors" /id="U1246" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.515484515484515" /psig="0.731268731268731" /xcortree=141 /SigmaFactorBS="aagaaggcttttttcattaacacataaaTCTTTGACatgtta aataggcTGTATTGTAATGGGATGTAAacaagagattgtgaatcgccacgggggtgat a" /listShort="ylbC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1566336 /Source="Nicolas_upshifts" /id="U1246" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.515484515484515" /psig="0.731268731268731" /xcortree=141 /SigmaFactorBS="aagaaggcttttttcattaacacataaaTCTTTGACatgtta aataggcTGTATTGTAATGGGATGTAAacaagagattgtgaatcgccacgggggtgat a" /listShort="ylbC" /GFF_Attribute="listLong" CDS 1566379..1567419 /gene="ylbC" /locus_tag="BSU_14960" /old_locus_tag="BSU14960" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_389379.1" /db_xref="EnsemblGenomes-Gn:BSU14960" /db_xref="EnsemblGenomes-Tr:CAB13369" /db_xref="GOA:O34586" /db_xref="InterPro:IPR014044" /db_xref="InterPro:IPR029410" /db_xref="InterPro:IPR035940" /db_xref="SubtiList:BG13355" /db_xref="UniProtKB/Swiss-Prot:O34586" /translation="MKNILRAMVILLIICGTYVLFIQYGSVPEKKSNDSEPQVSNEEA QSGKRIHMPTSGLLSFMGKHADEVTKKLGEPERIDPSAYDYDWWVYNQGKDQYIQIGV LNNKVVTLFASGNDINAKPFKIGESTGEVFKTTQVAPFVNVEYKGNSYRFEFSEEDIN TRPTVKVGKMYVQLYMDKFEGKLSSIRAFDAQTFVKQRPYEVVYRGELIKPKAVSDEK WKKIQTTSEKQILDLTNVIRVKHGLAKLEWDQPTAEVAFGHSEDMKENNYFSHVSKKY GSLKDRLEEGHVDFQQAGENIAYNYVDGPAAVEGWLNSEGHRKALLNSDYTHLGVGVD RKYYTQNFIKRW*" gene 1566379..1567419 /gene="ylbC" /locus_tag="BSU_14960" /old_locus_tag="BSU14960" promotor_-10 complement(1567342..1567360) /Source="Nicolas_upshift_promotors" /id="U1247" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.992007992007992" /psig="0.992007992007992" /xcortree=1068 /SigmaFactorBS="aataaagttttgggtgtaatatttccGGTCTActccgacacc aagatGCGTATAATCTGAATTCAGaagcgcttttcgatggccttcgctattcagccag c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1567347) /Source="Nicolas_upshifts" /id="U1247" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.992007992007992" /psig="0.992007992007992" /xcortree=1068 /SigmaFactorBS="aataaagttttgggtgtaatatttccGGTCTActccgacacc aagatGCGTATAATCTGAATTCAGaagcgcttttcgatggccttcgctattcagccag c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(1567376..1567381) /Source="Nicolas_upshift_promotors" /id="U1247" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.992007992007992" /psig="0.992007992007992" /xcortree=1068 /SigmaFactorBS="aataaagttttgggtgtaatatttccGGTCTActccgacacc aagatGCGTATAATCTGAATTCAGaagcgcttttcgatggccttcgctattcagccag c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 1567399 /Source="Nicolas_upshifts" /id="D847" /incds=0 /nref=84 /ntot=252 /MaxReadThrough="1.59604" /MaxDrop="4.17709" /score="-1.16631837" /energy="-8.1" /TU="NA" /idTUdmin="U1243" /TUdmin="-4" /isTUend="TRUE" promotor_-35 1567583..1567592 /Source="Nicolas_upshift_promotors" /id="U1248" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp="0.976023976023976" /psig="0.976023976023976" /xcortree=1306 /SigmaFactorBS="aaaattcatttgggaatgaatatAGGCGAACACaatgcccga caaaACGATACATTGTAGTAGGTAacgattttcggagggggtgaggattgtggcgaat c" /listShort="ylbD, ylbE" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1567606..1567625 /Source="Nicolas_upshift_promotors" /id="U1248" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp="0.976023976023976" /psig="0.976023976023976" /xcortree=1306 /SigmaFactorBS="aaaattcatttgggaatgaatatAGGCGAACACaatgcccga caaaACGATACATTGTAGTAGGTAacgattttcggagggggtgaggattgtggcgaat c" /listShort="ylbD, ylbE" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1567620 /Source="Nicolas_upshifts" /id="U1248" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp="0.976023976023976" /psig="0.976023976023976" /xcortree=1306 /SigmaFactorBS="aaaattcatttgggaatgaatatAGGCGAACACaatgcccga caaaACGATACATTGTAGTAGGTAacgattttcggagggggtgaggattgtggcgaat c" /listShort="ylbD, ylbE" /GFF_Attribute="listLong" CDS 1567651..1568049 /gene="ylbD" /locus_tag="BSU_14970" /old_locus_tag="BSU14970" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2b: Function from indirect experimental evidences (e.g. phenotypes); PubMedId: 19775244, 22882546; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="sporulation-related protein (coat)" /protein_id="NP_389380.1" /db_xref="EnsemblGenomes-Gn:BSU14970" /db_xref="EnsemblGenomes-Tr:CAB13370" /db_xref="InterPro:IPR025953" /db_xref="SubtiList:BG13356" /db_xref="UniProtKB/Swiss-Prot:O34880" /translation="MANQHANHSINDFKQFVKKHPKLIKEVRKEQRSWQDVYENWVLF GESDPIWDPYREPEEASEAVPETPQKNDFVSKMVTAVKKMDVNQMNEQINKMSQSISS LQSLLNTFSGSGQKHSQPGSGQHPFSFRKD*" gene 1567651..1568049 /gene="ylbD" /locus_tag="BSU_14970" /old_locus_tag="BSU14970" downshifts complement(1567655) /Source="Nicolas_upshifts" /id="D848" /incds=0 /nref=2 /ntot=11 /MaxReadThrough="2.37349" /MaxDrop="4.0378" /score="40.2648817" /energy="-14.3" /TU="NA" /idTUdmin="U1247" /TUdmin="-374" /isTUend="FALSE" CDS 1568065..1568304 /gene="ylbE" /locus_tag="BSU_14980" /old_locus_tag="BSU14980" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 22882546" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_389381.1" /db_xref="EnsemblGenomes-Gn:BSU14980" /db_xref="EnsemblGenomes-Tr:CAB13371" /db_xref="InterPro:IPR025613" /db_xref="SubtiList:BG13357" /db_xref="UniProtKB/Swiss-Prot:O34958" /translation="MRKEVQEYILANEERKRFIREQPIWYRRLSRKPDDLSSFQLEMM NFYEKTIPHRVNQFTNGIQMAQMMMQMFQAMRTKD*" gene 1568065..1568304 /gene="ylbE" /locus_tag="BSU_14980" /old_locus_tag="BSU14980" downshifts 1568283 /Source="Nicolas_upshifts" /id="D849" /incds=0 /nref=3 /ntot=17 /MaxReadThrough="2.09257" /MaxDrop="4.65792" /score="-7.8200921" /energy="-5.1" /TU="NA" /idTUdmin="U1248" /TUdmin=0 /isTUend="TRUE" promotor_-35 1568371..1568378 /Source="Nicolas_upshift_promotors" /id="U1249" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.974025974025974" /psig=1 /xcortree=2169 /SigmaFactorBS="cggtcataaggttttgttggcggctgcggttaagcatTTTCC AATtggctggtttCATGGTAAACTAACAACTGGaggtgcatgttatgtatgcgacgat g" /listShort="ylbF, ylbG, NA, S548, S549, ylbH, coaD, S550, S552, ylbK, ylbL" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1568389..1568408 /Source="Nicolas_upshift_promotors" /id="U1249" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.974025974025974" /psig=1 /xcortree=2169 /SigmaFactorBS="cggtcataaggttttgttggcggctgcggttaagcatTTTCC AATtggctggtttCATGGTAAACTAACAACTGGaggtgcatgttatgtatgcgacgat g" /listShort="ylbF, ylbG, NA, S548, S549, ylbH, coaD, S550, S552, ylbK, ylbL" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1568394 /Source="Nicolas_upshifts" /id="U1249" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.974025974025974" /psig=1 /xcortree=2169 /SigmaFactorBS="cggtcataaggttttgttggcggctgcggttaagcatTTTCC AATtggctggtttCATGGTAAACTAACAACTGGaggtgcatgttatgtatgcgacgat g" /listShort="ylbF, ylbG, NA, S548, S549, ylbH, coaD, S550, S552, ylbK, ylbL" /GFF_Attribute="listLong" CDS 1568420..1568869 /gene="ricF" /locus_tag="BSU_14990" /old_locus_tag="BSU14990" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:10712692, 15175311, 15661000, 23490197, 26434553, 27501195, 28295778" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10712692, 15175311, 15661000, 23490197, 26434553, 27501195, 28295778; Product type r: regulator" /codon_start=1 /transl_table=11 /product="subunit of a sporulation, competence and biofilmformation regulatory complex controlling RNase Y (RicAFTcomplex / FAD / two [4Fe-4S]2+)" /protein_id="NP_389382.1" /db_xref="EnsemblGenomes-Gn:BSU14990" /db_xref="EnsemblGenomes-Tr:CAB13372" /db_xref="GOA:O34412" /db_xref="InterPro:IPR010368" /db_xref="InterPro:IPR023378" /db_xref="SubtiList:BG13358" /db_xref="UniProtKB/Swiss-Prot:O34412" /translation="MYATMESVRLQSEAQQLAEMILQSETAENYRNCYKRLQEDEEAG RIIRSFIKIKEQYEDVQRFGKYHPDYREISRKMREIKRELDLNDKVADFKRAENELQS ILDEVSVEIGTAVSEHVKVPTGNPYFDGLSSCGGGCGSGGSCGCKVS*" gene 1568420..1568869 /gene="ricF" /locus_tag="BSU_14990" /old_locus_tag="BSU14990" downshifts 1568855 /Source="Nicolas_upshifts" /id="D850" /incds=0 /nref=1 /ntot=6 /MaxReadThrough="5.95111" /MaxDrop="2.83" /score="-4.2014677" /energy="-11.5" /TU="U1249" /idTUdmin="U1248" /TUdmin=572 /isTUend="FALSE" CDS 1568924..1569196 /gene="ylbG" /locus_tag="BSU_15000" /old_locus_tag="BSU15000" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 10712692, 21532344, 22333191" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_389383.1" /db_xref="EnsemblGenomes-Gn:BSU15000" /db_xref="EnsemblGenomes-Tr:CAB13373" /db_xref="GOA:O34658" /db_xref="InterPro:IPR016979" /db_xref="SubtiList:BG13359" /db_xref="UniProtKB/Swiss-Prot:O34658" /translation="MENRRQGMVVYLHSLKQSKMLRKFGNVHYVSKRLKYVVLYCDMD QIEKTMDKIASYSFVKKVEPSYKPFLKLEFESKLDKAKEYDYKIGI*" gene 1568924..1569196 /gene="ylbG" /locus_tag="BSU_15000" /old_locus_tag="BSU15000" S_feature complement(1569001..1569224) /Source="Nicolas_S_feature" /locus_tag="new_1569001_1569224_c" /HighExp="S8, S7, S4, S5, S6, S3, C30, BT, G135, C90" /AntisenseName="ylbG" /AntisenseCor="-0.668594452827031" /AntisenseRegPval="-35.5" /CDS_PredictionProba="NA" /TUshortSig="SigGF" /TUshortPSig="0.537" /TUlongSig="NA" /TUlongPSig="NA" /label="S546" misc_RNA 1569199..1569319 /gene="csfG" /locus_tag="BSU_misc_RNA_23" /product="sporulation-specific regulatory RNA" /experiment="publication(s) with functional evidences, PMID:21532344" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 21532344; Product type n: RNA" /function="15.7: Sporulation and germination" gene 1569199..1569319 /gene="csfG" /locus_tag="BSU_misc_RNA_23" S_feature complement(1569226..1569349) /Source="Nicolas_S_feature" /locus_tag="new_1569226_1569349_c" /HighExp="S3, S8, S7, G/S, S4, S5, Pyr, S6, B36, BT" /AntisenseName="NA" /AntisenseCor="-0.69279578575099399" /AntisenseRegPval="-39.1" /CDS_PredictionProba="NA" /TUshortSig="SigGF" /TUshortPSig="0.537" /TUlongSig="NA" /TUlongPSig="NA" /label="S547" downshifts complement(1569269) /Source="Nicolas_upshifts" /id="D851" /incds=0 /nref=61 /ntot=131 /MaxReadThrough="3.9368" /MaxDrop="7.78892" /score="40.2648817" /energy="-14.3" /TU="U1250" /idTUdmin="U1250" /TUdmin="-228" /isTUend="FALSE" S_feature 1569320..1569425 /Source="Nicolas_S_feature" /locus_tag="new_1569320_1569425" /HighExp="H2O2, Paraq, Oxctl, G180, G135, G150, Cold, C30, Diami, Glucon" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S548" promotor_-10 complement(1569350..1569362) /Source="Nicolas_upshift_promotors" /id="U1250" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.537462537462537" /psig="0.537462537462537" /xcortree=1087 /SigmaFactorBS="ttccaaacaatgaacgctaatcttgataaacaggTGTATAGg cagcatgatccttGTCCATACTATAAgcaacagcatctagaggatgttgttgccaacc g" /listShort="S547, S546" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1569357) /Source="Nicolas_upshifts" /id="U1250" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.537462537462537" /psig="0.537462537462537" /xcortree=1087 /SigmaFactorBS="ttccaaacaatgaacgctaatcttgataaacaggTGTATAGg cagcatgatccttGTCCATACTATAAgcaacagcatctagaggatgttgttgccaacc g" /listShort="S547, S546" /GFF_Attribute="listLong" promotor_-35 complement(1569377..1569383) /Source="Nicolas_upshift_promotors" /id="U1250" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.537462537462537" /psig="0.537462537462537" /xcortree=1087 /SigmaFactorBS="ttccaaacaatgaacgctaatcttgataaacaggTGTATAGg cagcatgatccttGTCCATACTATAAgcaacagcatctagaggatgttgttgccaacc g" /listShort="S547, S546" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1569406..1569410 /Source="Nicolas_upshift_promotors" /id="U1251" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.807192807192807" /psig=1 /xcortree=2460 /SigmaFactorBS="atcatgctgcctatacacctgtttatcaagattagcgttCAT TGtttggaagaatgcttTATGTTAAGATAGGATTGATttttttctatgtacatagcgg c" /listShort="S549, ylbH, coaD, S550" /listLong="S552, ylbK, ylbL" /label="promotor_-35" promotor_-10 1569426..1569445 /Source="Nicolas_upshift_promotors" /id="U1251" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.807192807192807" /psig=1 /xcortree=2460 /SigmaFactorBS="atcatgctgcctatacacctgtttatcaagattagcgttCAT TGtttggaagaatgcttTATGTTAAGATAGGATTGATttttttctatgtacatagcgg c" /listShort="S549, ylbH, coaD, S550" /listLong="S552, ylbK, ylbL" /label="promotor_-10" S_feature 1569427..1569518 /Source="Nicolas_S_feature" /locus_tag="new_1569427_1569518" /HighExp="H2O2, G135, Oxctl, Paraq, G180, dia0, G150, Lbexp, LBGexp, Mt0" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="1, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S549" upshifts 1569427 /Source="Nicolas_upshifts" /id="U1251" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.807192807192807" /psig=1 /xcortree=2460 /SigmaFactorBS="atcatgctgcctatacacctgtttatcaagattagcgttCAT TGtttggaagaatgcttTATGTTAAGATAGGATTGATttttttctatgtacatagcgg c" /listShort="S549, ylbH, coaD, S550" /listLong="S552, ylbK, ylbL" CDS 1569519..1570073 /gene="rsmD" /locus_tag="BSU_15010" /old_locus_tag="BSU15010" /EC_number="2.1.1.171" /function="18.1: Enzymes of unknown specificity" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 16014871, 17389639, 22535590, 22649054; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="16S rRNA m2G966 methyltransferase" /protein_id="NP_389384.2" /db_xref="EnsemblGenomes-Gn:BSU15010" /db_xref="EnsemblGenomes-Tr:CAB13374" /db_xref="GOA:O34331" /db_xref="InterPro:IPR004398" /db_xref="InterPro:IPR029063" /db_xref="SubtiList:BG13360" /db_xref="UniProtKB/Swiss-Prot:O34331" /translation="MRVISGSKKGRSLKAVAGTSTRPTTDKVKESIFNMIGPYFDGGR GLDLFAGSGGLGIEALSRGFEHCIFVDRDFKAIQTVKSNLKTLELTKHAQVYRNDAER ALHAAAKRETGFRGIFLDPPYKEQKLKALLTLIDEYQMLEEDGFIVAEHDREVELPET VGDLVMTRKETYGLTGVAIYKKRG*" gene 1569519..1570073 /gene="rsmD" /locus_tag="BSU_15010" /old_locus_tag="BSU15010" CDS 1570078..1570563 /gene="coaD" /locus_tag="BSU_15020" /old_locus_tag="BSU15020" /EC_number="2.7.7.3" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 10480925, 10939241, 16014871, 21912874; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="phosphopantetheine adenylyltransferase" /protein_id="NP_389385.1" /db_xref="EnsemblGenomes-Gn:BSU15020" /db_xref="EnsemblGenomes-Tr:CAB13375" /db_xref="GOA:O34797" /db_xref="InterPro:IPR001980" /db_xref="InterPro:IPR004821" /db_xref="InterPro:IPR014729" /db_xref="PDB:1O6B" /db_xref="SubtiList:BG13361" /db_xref="UniProtKB/Swiss-Prot:O34797" /translation="MASIAVCPGSFDPVTYGHLDIIKRGAHIFEQVYVCVLNNSSKKP LFSVEERCELLREVTKDIPNITVETSQGLLIDYAKRKNAKAILRGLRAVSDFEYEMQG TSVNRVLDESIETFFMMTNNQYSFLSSSIVKEVARYNGSVSEFVPPEVELALQQKFRQ G*" gene 1570078..1570563 /gene="coaD" /locus_tag="BSU_15020" /old_locus_tag="BSU15020" downshifts 1570530 /Source="Nicolas_upshifts" /id="D852" /incds=0 /nref=26 /ntot=196 /MaxReadThrough="3.45558" /MaxDrop="3.85134" /score="13.7782945" /energy="-7.8" /TU="U1249,U1251" /idTUdmin="U1251" /TUdmin="-1296" /isTUend="FALSE" CDS complement(1570574..1571800) /gene="spoVV" /locus_tag="BSU_15030" /old_locus_tag="BSU15030" /function="16.5: Explore" /function="16.13: Shape" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:12662922, 15849754, 16850406, 28945739" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12662922, 15849754, 16850406, 28945739; Product type t: transporter" /codon_start=1 /transl_table=11 /product="dipicolinic acid transporter (to the spore)" /protein_id="NP_389386.1" /db_xref="EnsemblGenomes-Gn:BSU15030" /db_xref="EnsemblGenomes-Tr:CAB13376" /db_xref="GOA:O34765" /db_xref="InterPro:IPR011642" /db_xref="InterPro:IPR014226" /db_xref="SubtiList:BG13362" /db_xref="UniProtKB/Swiss-Prot:O34765" /translation="MNLSKINTLLIASFFLFLTATVISHPQASFEASKTGLSMWWEVV FPSLLPFFILSELLIGFGIVRFVGVLLEPFMRPIFRVPGVGGFVLAMGMASGNPAGAK LTARLRQENQISRVEAERLASFTNSSNPLFIFGAVAVGFFQNASLGILLASAHYLGNL AVGLTMRSYGRKEEQHLRRKKTIPFPSVKDALHALHTARLAEKRPLGKILGDAVTSSV QTLLMVGGFIILFSVFNRLLSVVQLTDVLSVFTKGALTLFQLPTQLDIPLLSGMFEIT LGSKLVSETDVSLLQKAIIVSFILGFSGFSVQAQVAGILSETDIRFKPFFIARLLQGV YAAVFVMLLWKPLYTAWHDPYQYVFKSLNSSDMSTAFINGWNLLVQIGPAVTLCALFT YIIIFSYRLTNGTKKG*" gene complement(1570574..1571800) /gene="spoVV" /locus_tag="BSU_15030" /old_locus_tag="BSU15030" S_feature 1570575..1571849 /Source="Nicolas_S_feature" /locus_tag="new_1570575_1571849" /HighExp="H2O2, G135, Paraq, G150, G180, Oxctl, LBGexp, dia0, dia15, Mt0" /AntisenseName="ylbJ" /AntisenseCor="-0.54237424349391605" /AntisenseRegPval="-21.2" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="1, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S550" S_feature complement(1571801..1571902) /Source="Nicolas_S_feature" /locus_tag="new_1571801_1571902_c" /HighExp="LoTm, S3, S4, S5, T5.0H, M9-stat, T4.0H, S6, BT, T3.30H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigEF" /TUshortPSig="0.998" /TUlongSig="NA" /TUlongPSig="NA" /label="S551" promotor_-35 1571824..1571831 /Source="Nicolas_upshift_promotors" /id="U1252" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.932067932067932" /psig=1 /xcortree=1988 /SigmaFactorBS="acaagttcattcttacctccccgatgctaaaaaTGCCCAATg acatgtatatCATGATAAAATAATGTATGAtgtaaaacggccaagcagtacctgtcct c" /listShort="S552, ylbK, ylbL" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1571843..1571862 /Source="Nicolas_upshift_promotors" /id="U1252" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.932067932067932" /psig=1 /xcortree=1988 /SigmaFactorBS="acaagttcattcttacctccccgatgctaaaaaTGCCCAATg acatgtatatCATGATAAAATAATGTATGAtgtaaaacggccaagcagtacctgtcct c" /listShort="S552, ylbK, ylbL" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 1571851..1571980 /Source="Nicolas_S_feature" /locus_tag="new_1571851_1571980" /HighExp="Etha, dia15, dia5, Diami, H2O2, Lbtran, LBGtran, Paraq, G150, G135" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="1, 1" /TUlongSig="SigA" /TUlongPSig=1 /label="S552" upshifts 1571851 /Source="Nicolas_upshifts" /id="U1252" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.932067932067932" /psig=1 /xcortree=1988 /SigmaFactorBS="acaagttcattcttacctccccgatgctaaaaaTGCCCAATg acatgtatatCATGATAAAATAATGTATGAtgtaaaacggccaagcagtacctgtcct c" /listShort="S552, ylbK, ylbL" /GFF_Attribute="listLong" promotor_-10 complement(1571897..1571915) /Source="Nicolas_upshift_promotors" /id="U1253" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=985 /SigmaFactorBS="cctcctgcctgaattccctgtataccgaattctatGGTCTAa actgaacccctatgcTCGTATATTAGTACAAAGAatcaagaggacaggtactgcttgg c" /listShort="S551, ylbJ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1571912) /Source="Nicolas_upshifts" /id="U1253" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=985 /SigmaFactorBS="cctcctgcctgaattccctgtataccgaattctatGGTCTAa actgaacccctatgcTCGTATATTAGTACAAAGAatcaagaggacaggtactgcttgg c" /listShort="S551, ylbJ" /GFF_Attribute="listLong" promotor_-35 complement(1571932..1571937) /Source="Nicolas_upshift_promotors" /id="U1253" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=985 /SigmaFactorBS="cctcctgcctgaattccctgtataccgaattctatGGTCTAa actgaacccctatgcTCGTATATTAGTACAAAGAatcaagaggacaggtactgcttgg c" /listShort="S551, ylbJ" /GFF_Attribute="listLong" /label="promotor_-35" CDS 1571981..1572763 /gene="ylbK" /locus_tag="BSU_15040" /old_locus_tag="BSU15040" /EC_number="3.1.-.-" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 22720735; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative hydrolase" /protein_id="NP_389387.1" /db_xref="EnsemblGenomes-Gn:BSU15040" /db_xref="EnsemblGenomes-Tr:CAB13377" /db_xref="GOA:O34731" /db_xref="InterPro:IPR001423" /db_xref="InterPro:IPR002641" /db_xref="InterPro:IPR016035" /db_xref="SubtiList:BG13363" /db_xref="UniProtKB/Swiss-Prot:O34731" /translation="MAKPKIGLALGSGGARGLAHLGVLSSLHKHQIEVDMIAGSSMGA LVGSFYAAGHDVATMKKVAKAFKRRLYADYTVPKLGFLKGDRVRQLVHAYTFGKPIEE LQIPLGIVACDLQTGEKIVFRKGSVSDAVRASISIPGIFIPQRLDGRLLVDGAVVDRI PVSVVKDMGADIIIASDVSRVRKTETAVHIFDVIMQSMDILQNELVRHQTIAADIMIR PSLETYSSSSFANIEEMISAGEEATNRMISKIRKEIENWEGS*" gene 1571981..1572763 /gene="ylbK" /locus_tag="BSU_15040" /old_locus_tag="BSU15040" promotor_-35 1572543..1572549 /Source="Nicolas_upshift_promotors" /id="U1254" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.993006993006993" /psig="0.993006993006993" /xcortree=814 /SigmaFactorBS="ttccagggttcgaaaaactgaaacagcagTGCATATttttga tgtgattATGCAAAGTATGgatatactgcaaaatgaattagtgcggcatcaaacaatt g" /listShort="ylbL" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1572563..1572574 /Source="Nicolas_upshift_promotors" /id="U1254" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.993006993006993" /psig="0.993006993006993" /xcortree=814 /SigmaFactorBS="ttccagggttcgaaaaactgaaacagcagTGCATATttttga tgtgattATGCAAAGTATGgatatactgcaaaatgaattagtgcggcatcaaacaatt g" /listShort="ylbL" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1572574 /Source="Nicolas_upshifts" /id="U1254" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.993006993006993" /psig="0.993006993006993" /xcortree=814 /SigmaFactorBS="ttccagggttcgaaaaactgaaacagcagTGCATATttttga tgtgattATGCAAAGTATGgatatactgcaaaatgaattagtgcggcatcaaacaatt g" /listShort="ylbL" /GFF_Attribute="listLong" CDS 1572765..1573790 /gene="ylbL" /locus_tag="BSU_15050" /old_locus_tag="BSU15050" /function="16.11: Scavenge (Catabolism)" /function="18.1: Enzymes of unknown specificity" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative degradative enzyme" /protein_id="NP_389388.2" /db_xref="EnsemblGenomes-Gn:BSU15050" /db_xref="EnsemblGenomes-Tr:CAB13378" /db_xref="GOA:O34470" /db_xref="InterPro:IPR001478" /db_xref="InterPro:IPR008269" /db_xref="InterPro:IPR014721" /db_xref="InterPro:IPR020568" /db_xref="InterPro:IPR027065" /db_xref="InterPro:IPR036034" /db_xref="PDB:2KJP" /db_xref="SubtiList:BG13364" /db_xref="UniProtKB/Swiss-Prot:O34470" /translation="MLRKKHFSWMLVILILIAVLSFIKLPYYITKPGEATELASLIKV EGGYPEKGSLSLMTVKVGPANPFTYVWAKMHPYYEIVPDESIKEEGESDKEYMKRQLQ MMKSSQENAVIAAYQKAGKKVSYSFNGIYASSVVENMPAKGKIEVGDKIISADGKNYQ SAEKLIDYISSKKAGDKVTLKIEREEKEKRVTLTLKQFPDEPDRAGIGVSLYTDRNVK VEPDIDFEIENIGGPSAGLMMSLEIYNQLTKPDETKGYDIAGTGTIDVDGKVGPIGGI DQKVVAADKAGKDIFFAPNQNGASNSDYKNAVKTAKDIDSNMKIVPVDTMQDAIDYLN KLKAKST*" gene 1572765..1573790 /gene="ylbL" /locus_tag="BSU_15050" /old_locus_tag="BSU15050" downshifts 1573674 /Source="Nicolas_upshifts" /id="D853" /incds=1 /nref=59 /ntot=235 /MaxReadThrough="2.38639" /MaxDrop="3.52503" /score="19.0874959" /energy="-11.5" /TU="NA" /idTUdmin="U1249" /TUdmin=0 /isTUend="TRUE" CDS complement(1573807..1575054) /gene="ylbM" /locus_tag="BSU_15060" /old_locus_tag="BSU15060" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 16014871, 19215769; Product type f: factor" /codon_start=1 /transl_table=11 /product="putative component of the degradosome" /protein_id="NP_389389.1" /db_xref="EnsemblGenomes-Gn:BSU15060" /db_xref="EnsemblGenomes-Tr:CAB13379" /db_xref="InterPro:IPR008513" /db_xref="InterPro:IPR014729" /db_xref="SubtiList:BG13365" /db_xref="UniProtKB/Swiss-Prot:O34513" /translation="MKAVGLVVEYNPFHNGHLYHAQTAKLQTGCDTAVAVMSGHFLQR GEPAVVSKWARTKMALQSGVDLVIELPYLYAVQKADIFARGSVSILNELECEALFFGS ENGDIKPFLETAQLIDEHKHILNDRIKEELKKGASYPAAAAIAFSSILHTESALDLSK PNNILGYQYVTSILTGGYPMKPYTTARISSDYHDADLPEGENHIASATSIRKAMIGQN LEACLRFLPAASARELAAYRKSFGLWHTPESYFSYLKYSLSTVTARELQQVYEVEEGL EHRIIRSIRKSSSYQEFMELLKTKRYTWTRLQRMNTHILTRTKKQDMQKLLDNDKAPY IRLLGMTKKGQAYLSEKKKALSVPLVSKLSSFSHPALDLDVKASRIYSLPIEEPLRTE FDLQEYGHAPIRYDEDEQHFLNV*" gene complement(1573807..1575054) /gene="ylbM" /locus_tag="BSU_15060" /old_locus_tag="BSU15060" downshifts complement(1573834) /Source="Nicolas_upshifts" /id="D854" /incds=0 /nref=8 /ntot=182 /MaxReadThrough="1.58661" /MaxDrop="3.70777" /score="4.49214865" /energy="-11.5" /TU="NA" /idTUdmin="U1257" /TUdmin=775 /isTUend="FALSE" promotor_-35 1574971..1574977 /Source="Nicolas_upshift_promotors" /id="U1255" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.988011988011988" /psig="0.988011988011988" /xcortree=892 /SigmaFactorBS="atgtccgctcatgaccgcgacagccgtgtcacatccGGTTTG CagctttgctgtttGGGCATGATAAAggtgaccgttatgaaagggattatattcaacc a" /listShort="S553, ylbN" /listLong="rpmF" /label="promotor_-35" promotor_-10 1574991..1575002 /Source="Nicolas_upshift_promotors" /id="U1255" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.988011988011988" /psig="0.988011988011988" /xcortree=892 /SigmaFactorBS="atgtccgctcatgaccgcgacagccgtgtcacatccGGTTTG CagctttgctgtttGGGCATGATAAAggtgaccgttatgaaagggattatattcaacc a" /listShort="S553, ylbN" /listLong="rpmF" /label="promotor_-10" upshifts 1574995 /Source="Nicolas_upshifts" /id="U1255" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.988011988011988" /psig="0.988011988011988" /xcortree=892 /SigmaFactorBS="atgtccgctcatgaccgcgacagccgtgtcacatccGGTTTG CagctttgctgtttGGGCATGATAAAggtgaccgttatgaaagggattatattcaacc a" /listShort="S553, ylbN" /listLong="rpmF" CDS complement(1575051..1575236) /gene="ylzH" /locus_tag="BSU_15069" /old_locus_tag="BSU15069" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein,of unknown function" /protein_id="YP_003097727.1" /db_xref="EnsemblGenomes-Gn:BSU15069" /db_xref="EnsemblGenomes-Tr:CAX52618" /db_xref="UniProtKB/Swiss-Prot:C0H411" /translation="MIIAFKIVFVNIFSLQHNAAIEVSLTAEYAMHTLKTKIRRKSFH LQMYHTFLNIARKAEKI*" gene complement(1575051..1575236) /gene="ylzH" /locus_tag="BSU_15069" /old_locus_tag="BSU15069" promotor_-35 1575069..1575073 /Source="Nicolas_upshift_promotors" /id="U1256" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.872127872127872" /psig=1 /xcortree=2505 /SigmaFactorBS="aatccgacagctttcatattttttccgccttTCTTGctatgt ttaaaaacgTATGGTACATTTGCAAATGAaaactcttacgccttatttttgttttaag t" /listShort="S553, ylbN, rpmF" /listLong="ylbO" /label="promotor_-35" promotor_-10 1575089..1575108 /Source="Nicolas_upshift_promotors" /id="U1256" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.872127872127872" /psig=1 /xcortree=2505 /SigmaFactorBS="aatccgacagctttcatattttttccgccttTCTTGctatgt ttaaaaacgTATGGTACATTTGCAAATGAaaactcttacgccttatttttgttttaag t" /listShort="S553, ylbN, rpmF" /listLong="ylbO" /label="promotor_-10" S_feature 1575098..1575233 /Source="Nicolas_S_feature" /locus_tag="new_1575098_1575233" /HighExp="Cold, LoTm, Diami, Paraq, H2O2, Oxctl, G180, dia5, G135, LBGexp" /AntisenseName="ylzH" /AntisenseCor="-9.1134498265910996E-2" /AntisenseRegPval="-0.9" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigGF" /TUshortPSig="1, 0.988" /TUlongSig="NA" /TUlongPSig="NA" /label="S553" upshifts 1575098 /Source="Nicolas_upshifts" /id="U1256" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.872127872127872" /psig=1 /xcortree=2505 /SigmaFactorBS="aatccgacagctttcatattttttccgccttTCTTGctatgt ttaaaaacgTATGGTACATTTGCAAATGAaaactcttacgccttatttttgttttaag t" /listShort="S553, ylbN, rpmF" /listLong="ylbO" promotor_-10 complement(1575127..1575146) /Source="Nicolas_upshift_promotors" /id="U1257" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.502497502497502" /psig="0.988011988011988" /xcortree=2270 /SigmaFactorBS="tctttacagcataatgctgccattgaagtaTCGTTGACagcg gaatatgctATGCATACACTTAAAACAAAaataaggcgtaagagttttcatttgcaaa t" /listShort="ylbM" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1575137) /Source="Nicolas_upshifts" /id="U1257" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.502497502497502" /psig="0.988011988011988" /xcortree=2270 /SigmaFactorBS="tctttacagcataatgctgccattgaagtaTCGTTGACagcg gaatatgctATGCATACACTTAAAACAAAaataaggcgtaagagttttcatttgcaaa t" /listShort="ylbM" /GFF_Attribute="listLong" promotor_-35 complement(1575160..1575167) /Source="Nicolas_upshift_promotors" /id="U1257" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.502497502497502" /psig="0.988011988011988" /xcortree=2270 /SigmaFactorBS="tctttacagcataatgctgccattgaagtaTCGTTGACagcg gaatatgctATGCATACACTTAAAACAAAaataaggcgtaagagttttcatttgcaaa t" /listShort="ylbM" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1575204..1575211 /Source="Nicolas_upshift_promotors" /id="U1258" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.845154845154845" /psig=1 /xcortree=2657 /SigmaFactorBS="atggcagcattatgctgtaaagaaaaaatATTGACAAaaaca atcttaaaAGCTATAATCATGTTTGTTGctttcctgaggtgatacaaatgaaatggac g" /listShort="ylbN, rpmF, ylbO" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1575225..1575244 /Source="Nicolas_upshift_promotors" /id="U1258" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.845154845154845" /psig=1 /xcortree=2657 /SigmaFactorBS="atggcagcattatgctgtaaagaaaaaatATTGACAAaaaca atcttaaaAGCTATAATCATGTTTGTTGctttcctgaggtgatacaaatgaaatggac g" /listShort="ylbN, rpmF, ylbO" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1575235 /Source="Nicolas_upshifts" /id="U1258" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.845154845154845" /psig=1 /xcortree=2657 /SigmaFactorBS="atggcagcattatgctgtaaagaaaaaatATTGACAAaaaca atcttaaaAGCTATAATCATGTTTGTTGctttcctgaggtgatacaaatgaaatggac g" /listShort="ylbN, rpmF, ylbO" /GFF_Attribute="listLong" CDS 1575264..1575782 /gene="ylbN" /locus_tag="BSU_15070" /old_locus_tag="BSU15070" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 11700356, 22720735" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_389390.1" /db_xref="EnsemblGenomes-Gn:BSU15070" /db_xref="EnsemblGenomes-Tr:CAB13380" /db_xref="InterPro:IPR003772" /db_xref="SubtiList:BG13366" /db_xref="UniProtKB/Swiss-Prot:O34445" /translation="MKWTIYQLHQMPKQSFEFDETVELNELTKLNSDIRRISPVRVKG RADIKSKQVSFDFTISGEMLLPCSRTLVDVPYPFEISTKELFIFHHTDDIEDDDVHIV EDDTIDITPIVKEEILLEIPMQIFCESEQEKGAAPQEGKDWQVISEEDKKNQVDPRLA ALEKLLKQDDES*" gene 1575264..1575782 /gene="ylbN" /locus_tag="BSU_15070" /old_locus_tag="BSU15070" CDS 1575804..1575983 /gene="rpmF" /locus_tag="BSU_15080" /old_locus_tag="BSU15080" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 12682299; Product type f : factor" /codon_start=1 /transl_table=11 /product="ribosomal protein L32" /protein_id="NP_389391.1" /db_xref="EnsemblGenomes-Gn:BSU15080" /db_xref="EnsemblGenomes-Tr:CAB13381" /db_xref="GOA:O34687" /db_xref="InterPro:IPR002677" /db_xref="InterPro:IPR011332" /db_xref="PDB:3J3V" /db_xref="PDB:3J3W" /db_xref="PDB:3J9W" /db_xref="PDB:5NJT" /db_xref="SubtiList:BG12668" /db_xref="UniProtKB/Swiss-Prot:O34687" /translation="MAVPFRRTSKMKKRLRRTHFKLNVPGMTECPSCGEMKLSHRVCK ACGSYNGKDINVKSN*" gene 1575804..1575983 /gene="rpmF" /locus_tag="BSU_15080" /old_locus_tag="BSU15080" downshifts 1575963 /Source="Nicolas_upshifts" /id="D855" /incds=0 /nref=232 /ntot=266 /MaxReadThrough="5.64002" /MaxDrop="7.70407" /score="53.0065581" /energy="-17.1" /TU="U1258" /idTUdmin="U1256" /TUdmin=0 /isTUend="TRUE" upshifts complement(1576006) /Source="Nicolas_upshifts" /id="U1259" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.946053946053946" /psig=0 /xcortree=65 /SigmaFactorBS="actatttgcactcacaaattttccgcaagctgacaggaagag aaaaagaaaaaGCGCagggctttcaccctgcgcttttctcattagttactttttacat t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" misc_feature complement(1576010..1576013) /Source="Nicolas_upshift_promotors" /id="U1259" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.946053946053946" /psig=0 /xcortree=65 /SigmaFactorBS="actatttgcactcacaaattttccgcaagctgacaggaagag aaaaagaaaaaGCGCagggctttcaccctgcgcttttctcattagttactttttacat t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" promotor_-35 1576064..1576069 /Source="Nicolas_upshift_promotors" /id="U1260" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1162 /SigmaFactorBS="tcttcctgtcagcttgcggaaaatttgtgagtgcaaatAGTC TAtctaatctattaccgGCATATGTATGAGATAAATaagctgacatggagggagattg a" /listShort="ylbO" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1576085..1576103 /Source="Nicolas_upshift_promotors" /id="U1260" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1162 /SigmaFactorBS="tcttcctgtcagcttgcggaaaatttgtgagtgcaaatAGTC TAtctaatctattaccgGCATATGTATGAGATAAATaagctgacatggagggagattg a" /listShort="ylbO" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1576086 /Source="Nicolas_upshifts" /id="U1260" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1162 /SigmaFactorBS="tcttcctgtcagcttgcggaaaatttgtgagtgcaaatAGTC TAtctaatctattaccgGCATATGTATGAGATAAATaagctgacatggagggagattg a" /listShort="ylbO" /GFF_Attribute="listLong" CDS 1576129..1576710 /gene="gerR" /locus_tag="BSU_15090" /old_locus_tag="BSU15090" /function="16.5: Explore" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:15621419, 20435725" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15621419, 20435725; Product type r: regulator" /codon_start=1 /transl_table=11 /product="DNA-binding regulator" /protein_id="NP_389392.1" /db_xref="EnsemblGenomes-Gn:BSU15090" /db_xref="EnsemblGenomes-Tr:CAB13382" /db_xref="GOA:O34549" /db_xref="InterPro:IPR009057" /db_xref="InterPro:IPR014243" /db_xref="InterPro:IPR017930" /db_xref="SubtiList:BG13367" /db_xref="UniProtKB/Swiss-Prot:O34549" /translation="MTITRQDAWTQDEDLLLAEVVLRHIREGGTQLSAFEEVGRALTR TAAACGFRWNSYVRKQYQSGIELAKKQRKELRKQIGVHSVNMPNSMKQTASASSEGKR DLSIQDVIQFLEQFKETPSAQEFQLEREKLKEQIQSLQKELEDLRSENQTLRNQLEMT EEDYKALIDIMDRARKMVVSKEDGRMKKAAQET*" gene 1576129..1576710 /gene="gerR" /locus_tag="BSU_15090" /old_locus_tag="BSU15090" downshifts 1576711 /Source="Nicolas_upshifts" /id="D856" /incds=0 /nref=56 /ntot=139 /MaxReadThrough="2.70626" /MaxDrop="5.6861" /score="-7.71867756" /energy="-12.8" /TU="U1260" /idTUdmin="U1258" /TUdmin=0 /isTUend="TRUE" CDS complement(1576767..1577249) /gene="ylbP" /locus_tag="BSU_15100" /old_locus_tag="BSU15100" /EC_number="2.3.1.-" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative acetyltransferase" /protein_id="NP_389393.2" /db_xref="EnsemblGenomes-Gn:BSU15100" /db_xref="EnsemblGenomes-Tr:CAB13383" /db_xref="GOA:O34468" /db_xref="InterPro:IPR000182" /db_xref="InterPro:IPR016181" /db_xref="InterPro:IPR017274" /db_xref="PDB:2PR1" /db_xref="SubtiList:BG13368" /db_xref="UniProtKB/Swiss-Prot:O34468" /translation="MTKVERLLINYKTLEEFKKFKEYGIQELSMLEELQDNIIENDST SPFYGIYFGDKLVARMSLYQVNGKSNPYFDNRQDYLELWKLEVLPGYQNRGYGRALVE FAKSFKMPIRTNPRMKSAEFWNKMNFKTVKYDMARDKGENPLIWHPDMDREMTPGESA *" gene complement(1576767..1577249) /gene="ylbP" /locus_tag="BSU_15100" /old_locus_tag="BSU15100" downshifts complement(1576786) /Source="Nicolas_upshifts" /id="D857" /incds=0 /nref=90 /ntot=231 /MaxReadThrough="3.90092" /MaxDrop="6.59996" /score="14.5482917" /energy="-14.5" /TU="U1261" /idTUdmin="U1261" /TUdmin="-615" /isTUend="FALSE" downshifts 1577239 /Source="Nicolas_upshifts" /id="D858" /incds=0 /nref=1 /ntot=24 /MaxReadThrough="3.3013" /MaxDrop="4.42908" /score="-7.71867756" /energy="-12.8" /TU="NA" /idTUdmin="U1260" /TUdmin=418 /isTUend="FALSE" promotor_-10 complement(1577272..1577291) /Source="Nicolas_upshift_promotors" /id="U1261" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.45954045954046" /psig=1 /xcortree=358 /SigmaFactorBS="cttctcaaagatcccatgtgcttaaaattaaagtttaaaTAT TTGGAttttttaaataaaGCGTTTACAATATATGTAGAaacaacaaagggggagattt g" /listShort="ylbP" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1577291) /Source="Nicolas_upshifts" /id="U1261" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.45954045954046" /psig=1 /xcortree=358 /SigmaFactorBS="cttctcaaagatcccatgtgcttaaaattaaagtttaaaTAT TTGGAttttttaaataaaGCGTTTACAATATATGTAGAaacaacaaagggggagattt g" /listShort="ylbP" /GFF_Attribute="listLong" promotor_-35 complement(1577305..1577312) /Source="Nicolas_upshift_promotors" /id="U1261" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.45954045954046" /psig=1 /xcortree=358 /SigmaFactorBS="cttctcaaagatcccatgtgcttaaaattaaagtttaaaTAT TTGGAttttttaaataaaGCGTTTACAATATATGTAGAaacaacaaagggggagattt g" /listShort="ylbP" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1577349..1577355 /Source="Nicolas_upshift_promotors" /id="U1262" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.826173826173826" /psig=1 /xcortree=1857 /SigmaFactorBS="aatatttaaactttaattttaagcacatgggatctttgagAA GTAATttcttcttactTCTGCTATGATAATACGTAAatgctaaattgggtgtgacatc a" /listShort="ylbQ, yllA" /listLong="S554, mraZ, mraW, ftsL, pbpB" /label="promotor_-35" promotor_-10 1577367..1577386 /Source="Nicolas_upshift_promotors" /id="U1262" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.826173826173826" /psig=1 /xcortree=1857 /SigmaFactorBS="aatatttaaactttaattttaagcacatgggatctttgagAA GTAATttcttcttactTCTGCTATGATAATACGTAAatgctaaattgggtgtgacatc a" /listShort="ylbQ, yllA" /listLong="S554, mraZ, mraW, ftsL, pbpB" /label="promotor_-10" upshifts 1577369 /Source="Nicolas_upshifts" /id="U1262" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.826173826173826" /psig=1 /xcortree=1857 /SigmaFactorBS="aatatttaaactttaattttaagcacatgggatctttgagAA GTAATttcttcttactTCTGCTATGATAATACGTAAatgctaaattgggtgtgacatc a" /listShort="ylbQ, yllA" /listLong="S554, mraZ, mraW, ftsL, pbpB" CDS 1577409..1578305 /gene="panE" /locus_tag="BSU_15110" /old_locus_tag="BSU15110" /EC_number="1.1.1.169" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:1844812, 10736170, 23894131" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1844812, 10736170, 23894131; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="2-dehydropantoate 2-reductase" /protein_id="NP_389394.1" /db_xref="EnsemblGenomes-Gn:BSU15110" /db_xref="EnsemblGenomes-Tr:CAB13384" /db_xref="GOA:O34661" /db_xref="InterPro:IPR003710" /db_xref="InterPro:IPR008927" /db_xref="InterPro:IPR013328" /db_xref="InterPro:IPR013332" /db_xref="InterPro:IPR013752" /db_xref="InterPro:IPR036291" /db_xref="PDB:3EGO" /db_xref="SubtiList:BG13369" /db_xref="UniProtKB/Swiss-Prot:O34661" /translation="MKIGIIGGGSVGLLCAYYLSLYHDVTVVTRRQEQAAAIQSEGIR LYKGGEEFRADCSADTSINSDFDLLVVTVKQHQLQSVFSSLERIGKTNILFLQNGMGH IHDLKDWHVGHSIYVGIVEHGAVRKSDTAVDHTGLGAIKWSAFDDAEPDRLNILFQHN HSDFPIYYETDWYRLLTGKLIVNACINPLTALLQVKNGELLTTPAYLAFMKLVFQEAC RILKLENEEKAWERVQAVCGQTKENRSSMLVDVIGGRQTEADAIIGYLLKEASLQGLD AVHLEFLYGSIKALERNTNKVF*" gene 1577409..1578305 /gene="panE" /locus_tag="BSU_15110" /old_locus_tag="BSU15110" CDS 1578376..1579995 /gene="bshC" /locus_tag="BSU_15120" /old_locus_tag="BSU15120" /EC_number="6.-.-.-" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:16169927, 19578333, 20308541, 20799687, 25496067" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16169927, 19578333, 20308541, 20799687, 25496067; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="malate glucosamine cysteine ligase" /protein_id="NP_389395.2" /db_xref="EnsemblGenomes-Gn:BSU15120" /db_xref="EnsemblGenomes-Tr:CAB13385" /db_xref="GOA:P55342" /db_xref="InterPro:IPR011199" /db_xref="PDB:4WBD" /db_xref="SubtiList:BG11424" /db_xref="UniProtKB/Swiss-Prot:P55342" /translation="MQLTELSIKNQNVFVQHYIDGKEEMSSFFDYSIHHKDMWRERLE DLSSRFFAREELAAYLTSYHNKFGSSAMQSAIEKLKDPSSAAVVGGQQAGLLTGPLYT IHKIISIIVLAKQQEKELQVPVIPIFWVAGEDHDLDEINFVHTSEENGPVKKKLPQSY WKKSSAASTSLDQEKCAAWIDDVFAAFEETDHTNTLLDNVKRCLRESVTFTDFFELLI ADLFQEEGLVLLNSGDPGIKKLETAMFQKILRENDELARAVSDQQAFMRQAGYKPIIE SGKEQANLFYEYEDERFLIEKDNGRFVIKELDLGWTRDELHTHMEEHPERFSNNVVTR PLMQEFLIPTLAFIAGPGEINYWGELKQAFAVMGFKMPPVMPRLNITILERHIEKKLA ERNISLQDAIERGTENQRETYFERQIPEEFTAVMDQAKSQIEAIHKTVRQEALKVDQS LEPLLLKNAAFIQDQLQFLERTVMKRIEEKEGYVLKDYERIQNSIKPLLAPQERIWNI MYYLNRYGPKFFTTFKNLPFSFQNQHQVVKL*" gene 1578376..1579995 /gene="bshC" /locus_tag="BSU_15120" /old_locus_tag="BSU15120" downshifts 1579967 /Source="Nicolas_upshifts" /id="D859" /incds=0 /nref=1 /ntot=16 /MaxReadThrough="3.87099" /MaxDrop="3.76832" /score="34.9463932" /energy="-8.3" /TU="U1262" /idTUdmin="U1262" /TUdmin="-66" /isTUend="FALSE" promotor_-35 1580029..1580032 /Source="Nicolas_upshift_promotors" /id="U1263" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.501498501498502" /psig="0.955044955044955" /xcortree=3206 /SigmaFactorBS="aaactttgaaataaagttttaaagaaccctgactagttcagg GTTTttttttatgggtaaACAGTGTAAAATGAAGTTGTggagcgaagtggtgaatagt g" /listShort="S554, mraZ, mraW, ftsL, pbpB" /GFF_Attribute="listLong" /label="promotor_-35" S_feature 1580047..1580120 /Source="Nicolas_S_feature" /locus_tag="new_1580047_1580120" /HighExp="M9-stat, T5.0H, T3.0H, Lbstat, Lbtran, T2.30H, T1.30H, M0t90, T1.0H, T4.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.955" /TUlongSig="SigA" /TUlongPSig=1 /label="S554" promotor_-10 1580047..1580066 /Source="Nicolas_upshift_promotors" /id="U1263" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.501498501498502" /psig="0.955044955044955" /xcortree=3206 /SigmaFactorBS="aaactttgaaataaagttttaaagaaccctgactagttcagg GTTTttttttatgggtaaACAGTGTAAAATGAAGTTGTggagcgaagtggtgaatagt g" /listShort="S554, mraZ, mraW, ftsL, pbpB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1580047 /Source="Nicolas_upshifts" /id="U1263" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.501498501498502" /psig="0.955044955044955" /xcortree=3206 /SigmaFactorBS="aaactttgaaataaagttttaaagaaccctgactagttcagg GTTTttttttatgggtaaACAGTGTAAAATGAAGTTGTggagcgaagtggtgaatagt g" /listShort="S554, mraZ, mraW, ftsL, pbpB" /GFF_Attribute="listLong" downshifts complement(1580104) /Source="Nicolas_upshifts" /id="D860" /incds=0 /nref=17 /ntot=137 /MaxReadThrough="3.30554" /MaxDrop="4.47473" /score="-9.92306593" /energy="-12" /TU="NA" /idTUdmin="U1264" /TUdmin=1149 /isTUend="FALSE" CDS 1580121..1580552 /gene="mraZ" /locus_tag="BSU_15130" /old_locus_tag="BSU15130" /function="16.13: Shape" /function="16.9: Replicate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 10572301, 15939023, 16511046, 24659771, 22720735; Product type r: regulator" /codon_start=1 /transl_table=11 /product="inhibitor of RsmH and transcriptional regulator" /protein_id="NP_389396.1" /db_xref="EnsemblGenomes-Gn:BSU15130" /db_xref="EnsemblGenomes-Tr:CAB13386" /db_xref="GOA:P55343" /db_xref="InterPro:IPR003444" /db_xref="InterPro:IPR007159" /db_xref="InterPro:IPR020603" /db_xref="InterPro:IPR035642" /db_xref="InterPro:IPR035644" /db_xref="SubtiList:BG11425" /db_xref="UniProtKB/Swiss-Prot:P55343" /translation="MFMGEYQHTIDAKGRMIVPAKFREGLGEQFVLTRGLDQCLFGYP MHEWKQIEEKLKALPLTKKDARAFTRFFFSGATECELDKQGRVNIASSLLNYAKLEKE CVVIGVSNRIELWSKVIWEQYTEEQEDSFAEIAENMIGFDI*" gene 1580121..1580552 /gene="mraZ" /locus_tag="BSU_15130" /old_locus_tag="BSU15130" CDS 1580622..1581557 /gene="rsmH" /locus_tag="BSU_15140" /old_locus_tag="BSU15140" /EC_number="2.1.1.199" /function="16.6: Maintain" /function="16.13: Shape" /function="16.9: Replicate" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 9294438, 9721276, 10572301, 16849811, 19965768, 20924196, 22561317, 27711192; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="16S rRNA m4C1402 methyltransferase" /protein_id="NP_389397.1" /db_xref="EnsemblGenomes-Gn:BSU15140" /db_xref="EnsemblGenomes-Tr:CAB13387" /db_xref="GOA:Q07876" /db_xref="InterPro:IPR002903" /db_xref="InterPro:IPR023397" /db_xref="InterPro:IPR029063" /db_xref="SubtiList:BG10219" /db_xref="UniProtKB/Swiss-Prot:Q07876" /translation="MFQHKTVLLRETVDGLNIKPDGTYVDCTLGGAGHSTYLLQQLSE KGRLIAFDQDDTALQHAKEVLSDYKGQLILIKSNFRYLKEYLNEQGVTEVDGILFDLG VSSPQLDTPERGFSYHHDAPLDMRMDQSATLSAKEVVNEWRYEDLVRIFFKYGEEKFS KQIARKIEEARMKSPIQTTGQLVDLIKDAIPAPARRSGGHPAKRVFQAIRIAVNDELR VFEEALEQAIEVLKPGGRVSVITFHSLEDRICKTTFKEKSSLPELPPGLPVIPEEFEP ELKLITRKPITASQEELEENNRARSAKLRIAEKRK*" gene 1580622..1581557 /gene="rsmH" /locus_tag="BSU_15140" /old_locus_tag="BSU15140" S_feature complement(1581224..1582676) /Source="Nicolas_S_feature" /locus_tag="new_1581224_1582676_c" /HighExp="Salt, Sw, B60, Etha, M9-stat, Gly, C30, LPhT, BC, B36" /AntisenseName="ftsL" /AntisenseCor="-0.195961042435877" /AntisenseRegPval="-2.9" /CDS_PredictionProba="NA" /TUshortSig="SigB" /TUshortPSig="0.995" /TUlongSig="NA" /TUlongPSig="NA" /label="S555" CDS 1581597..1581950 /gene="ftsL" /locus_tag="BSU_15150" /old_locus_tag="BSU15150" /function="16.3: Control" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:10792716, 10844672, 11994149, 16549676, 16936019, 17020588, 22720735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10792716, 10844672, 11994149, 16549676, 16936019, 17020588, 22720735; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="cell-division protein" /protein_id="NP_389398.1" /db_xref="EnsemblGenomes-Gn:BSU15150" /db_xref="EnsemblGenomes-Tr:CAB13388" /db_xref="GOA:Q07867" /db_xref="InterPro:IPR011922" /db_xref="SubtiList:BG10220" /db_xref="UniProtKB/Swiss-Prot:Q07867" /translation="MSNLAYQPEKQQRHAISPEKKVIVKKRASITLGEKVLLVLFAAA VLSVSLLIVSKAYAAYQTNIEVQKLEEQISSENKQIGDLEKSVADLSKPQRIMDIAKK NGLNLKDKKVKNIQE*" gene 1581597..1581950 /gene="ftsL" /locus_tag="BSU_15150" /old_locus_tag="BSU15150" CDS 1581947..1584097 /gene="pbpB" /locus_tag="BSU_15160" /old_locus_tag="BSU15160" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:8636036, 10411726, 12682299, 14731276" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8636036, 10411726, 12682299, 14731276; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="penicillin-binding protein 2B" /protein_id="NP_389399.2" /db_xref="EnsemblGenomes-Gn:BSU15160" /db_xref="EnsemblGenomes-Tr:CAB13389" /db_xref="GOA:Q07868" /db_xref="InterPro:IPR001460" /db_xref="InterPro:IPR005311" /db_xref="InterPro:IPR005543" /db_xref="InterPro:IPR012338" /db_xref="InterPro:IPR036138" /db_xref="SubtiList:BG10221" /db_xref="UniProtKB/Swiss-Prot:Q07868" /translation="MIQMPKKNKFMNRGAAILSICFALFFFVILGRMAYIQITGKANG EVLATKATEQHEKKRTIEASRGSILDRKGKVIAEDTATYKLIAILDKKMTTDVKHPQH VVNKEKTAEALSKVINLDKADILDILNKDAKQVEFGSAGRDITYSQKQKIEKMKLPGI SFLRDTKRYYPNGVFASNLIGYAEVDEETNEISGAMGLEKVLDKYLKERDGYVTYESD KSGWELPNSKNKITAPKNGDNVYLTIDQKIQTFLEDSMTKVAQKYNPKKIMAAVVDPK TGKVLAMGQRPSFDPNKRDVTNYYNDLISYAYEPGSTMKIFTLAAAMQENVFNANEKY KSGTFEVGGAPVKDHNNGVGWGPTTYHDGVLRSSNVAFAKLAKEKLGYDRLNQYLHKF NFYQKTGIDLPGEVSSKINFKYEFDKASTAYGQASAVTPIQQIQAATAIANDGKMMKP YVIDHIVDPDKDKTIYQNKPESAGTPISASTAKKVRDILGEVVTSKIGTGQAYKIEGF DVAGKTGTAQIAGKGGYLDGTDNYIFSFMGMAPKDDPELLIYVAVQQPQLKAGQSSSD PVSEIFNPTMKNSLHYLNIEPTEKSDSDKEETKAQTMPDLTDQTVAAAQKKAKEENLT PIVIGSDVAVKEQYPKADEEVLTNQKVFLKTGGKIKMPDMTGWSRREVLQYGELAGIH IEVSGQGYAVSQSVKKDKEIKDKTVIKVKFKNPD*" gene 1581947..1584097 /gene="pbpB" /locus_tag="BSU_15160" /old_locus_tag="BSU15160" promotor_-10 complement(1582657..1582675) /Source="Nicolas_upshift_promotors" /id="U1264" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.995004995004995" /psig="0.995004995004995" /xcortree=233 /SigmaFactorBS="tatacttttgcgccacttttgtcatgctgtcttccaaaaaGG TTTGAattttctggtcaatGGTTAAATATACATTGTCAccattttttggcgctgtaat t" /listShort="S555" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1582676) /Source="Nicolas_upshifts" /id="U1264" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.995004995004995" /psig="0.995004995004995" /xcortree=233 /SigmaFactorBS="tatacttttgcgccacttttgtcatgctgtcttccaaaaaGG TTTGAattttctggtcaatGGTTAAATATACATTGTCAccattttttggcgctgtaat t" /listShort="S555" /GFF_Attribute="listLong" promotor_-35 complement(1582690..1582696) /Source="Nicolas_upshift_promotors" /id="U1264" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.995004995004995" /psig="0.995004995004995" /xcortree=233 /SigmaFactorBS="tatacttttgcgccacttttgtcatgctgtcttccaaaaaGG TTTGAattttctggtcaatGGTTAAATATACATTGTCAccattttttggcgctgtaat t" /listShort="S555" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 1584080 /Source="Nicolas_upshifts" /id="D861" /incds=0 /nref=237 /ntot=257 /MaxReadThrough="1.141" /MaxDrop="6.28059" /score="3.41058446" /energy="-7.4" /TU="NA" /idTUdmin="U1263" /TUdmin="-1" /isTUend="TRUE" promotor_-35 1584152..1584157 /Source="Nicolas_upshift_promotors" /id="U1265" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=993 /SigmaFactorBS="tatgcaggctttctttttttatgccttcagaggagcatcGTT CTAcctgtccaaattcagGCATAAAATGAAACAAGCCtaaataaggagtgaacggtct c" /listShort="spoVD" /listLong="S556, S557, murE, S558, mraY" /label="promotor_-35" promotor_-10 1584173..1584191 /Source="Nicolas_upshift_promotors" /id="U1265" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=993 /SigmaFactorBS="tatgcaggctttctttttttatgccttcagaggagcatcGTT CTAcctgtccaaattcagGCATAAAATGAAACAAGCCtaaataaggagtgaacggtct c" /listShort="spoVD" /listLong="S556, S557, murE, S558, mraY" /label="promotor_-10" upshifts 1584173 /Source="Nicolas_upshifts" /id="U1265" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=993 /SigmaFactorBS="tatgcaggctttctttttttatgccttcagaggagcatcGTT CTAcctgtccaaattcagGCATAAAATGAAACAAGCCtaaataaggagtgaacggtct c" /listShort="spoVD" /listLong="S556, S557, murE, S558, mraY" CDS 1584214..1586154 /gene="spoVD" /locus_tag="BSU_15170" /old_locus_tag="BSU15170" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:8244929, 8289242, 9006059, 28383125" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8244929, 8289242, 9006059, 28383125; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="transpeptidase penicillin-binding protein" /protein_id="NP_389400.2" /db_xref="EnsemblGenomes-Gn:BSU15170" /db_xref="EnsemblGenomes-Tr:CAB13390" /db_xref="GOA:Q03524" /db_xref="InterPro:IPR001460" /db_xref="InterPro:IPR005311" /db_xref="InterPro:IPR005543" /db_xref="InterPro:IPR011927" /db_xref="InterPro:IPR012338" /db_xref="InterPro:IPR036138" /db_xref="SubtiList:BG10222" /db_xref="UniProtKB/Swiss-Prot:Q03524" /translation="MRVSNVTVRKRLLFVLLFGVIVFLIIDTRLGYVQFVMGEKLTSL AKDSWSRNLPFEPERGEILDRNGVKLATNKSAPTVFVVPRQVQNPMKTSKQLAAVLNM SEEKVYKHVTKKASIEKITPEGRKISNEKAKEIKALDLKGVYVAEDSIRHYPFGSFLS HVLGFAGIDNQGLLGLEAYYDDDLKGEKGSVKFYTDAKGKKMPDEADDYTPPKDGLDM KLTVDSKVQTIMERELDNAEAKYHPDGMIAVAMNPKNGEILGMSSRPDFDPADYQSVD PSVYNRNLPVWSTYEPGSTFKIITLAAALEEQKVNLKRDQFYDKGHAEVDGARLRCWK RGGHGLQTYLEVVQNSCNPGFVELGERLGKEKLFKYIKDFGFGQKTGIDLQGEGTGIL FPLERVGPVEQATTAFGQGVSVTPIQQVAAVSAAVNGGTLYTPYIAKEWIDPVTKKTV KKQSPIAKKQVISEETSKQIRYALESVVAEGTGRNAFVEGYRVGGKTGTAQKVKDGKY LENNHIVSFIGFAPADDPSLVVYVAVDNPKGTIQFGGTVAAPIVGNIMRDSLPELGVK PRKNQIEKKYQWNDTKTIEVPNVVGMSVSDLESLLVNLNVDASGKGSKIVKQSPAAGT KVKEGSKIRVYLTEEDEKEAAD*" gene 1584214..1586154 /gene="spoVD" /locus_tag="BSU_15170" /old_locus_tag="BSU15170" promotor_-35 1585950..1585956 /Source="Nicolas_upshift_promotors" /id="U1266" /multdbtbs="-" /comp="M2" /sig="Sig-" /pcomp="0.435564435564436" /psig="0.435564435564436" /xcortree=578 /SigmaFactorBS="gaaaaatcaaatcgagaaaaaataccaatggaaCGACACAaa aacaatagaagtTCCGAATGTtgtagggatgtctgtctcagatcttgagtcactattg g" /listShort="S556, S557, murE, S558, mraY, murD, spoVE, S559, murG" /listLong="murB, divIB, ylxW, ylxX, sbp, S560, ftsA, ftsZ, S561, bpr" /label="promotor_-35" promotor_-10 1585971..1585979 /Source="Nicolas_upshift_promotors" /id="U1266" /multdbtbs="-" /comp="M2" /sig="Sig-" /pcomp="0.435564435564436" /psig="0.435564435564436" /xcortree=578 /SigmaFactorBS="gaaaaatcaaatcgagaaaaaataccaatggaaCGACACAaa aacaatagaagtTCCGAATGTtgtagggatgtctgtctcagatcttgagtcactattg g" /listShort="S556, S557, murE, S558, mraY, murD, spoVE, S559, murG" /listLong="murB, divIB, ylxW, ylxX, sbp, S560, ftsA, ftsZ, S561, bpr" /label="promotor_-10" upshifts 1585977 /Source="Nicolas_upshifts" /id="U1266" /multdbtbs="-" /comp="M2" /sig="Sig-" /pcomp="0.435564435564436" /psig="0.435564435564436" /xcortree=578 /SigmaFactorBS="gaaaaatcaaatcgagaaaaaataccaatggaaCGACACAaa aacaatagaagtTCCGAATGTtgtagggatgtctgtctcagatcttgagtcactattg g" /listShort="S556, S557, murE, S558, mraY, murD, spoVE, S559, murG" /listLong="murB, divIB, ylxW, ylxX, sbp, S560, ftsA, ftsZ, S561, bpr" downshifts 1586127 /Source="Nicolas_upshifts" /id="D862" /incds=0 /nref=19 /ntot=91 /MaxReadThrough="4.23549" /MaxDrop="4.37308" /score="-3.90592085" /energy="-13.6" /TU="U1265,U1266" /idTUdmin="U1265" /TUdmin="-91" /isTUend="FALSE" S_feature 1586172..1586239 /Source="Nicolas_S_feature" /locus_tag="new_1586172_1586239" /HighExp="C30, G180, G135, ferm, MG 15, G150, MG 45, MG-0.1, MG 10, MG 5" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="Sig-" /TUshortPSig="0.436" /TUlongSig="SigEF" /TUlongPSig=1 /label="S556" promotor_-35 1586209..1586213 /Source="Nicolas_upshift_promotors" /id="U1267" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.834165834165834" /psig=1 /xcortree=2534 /SigmaFactorBS="gaaaaaatgctgatatctttcaagattaGCTGGatgtatcct tttattTACGCTAAAATATGAACTGTatgcttaaaatcattaccacatcatttgatgt g" /listShort="S557, murE, S558, mraY, murD, spoVE, S559, murG, murB, divIB, ylxW, ylxX, sbp, S560, ftsA, ftsZ" /listLong="S561, bpr" /label="promotor_-35" promotor_-10 1586229..1586248 /Source="Nicolas_upshift_promotors" /id="U1267" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.834165834165834" /psig=1 /xcortree=2534 /SigmaFactorBS="gaaaaaatgctgatatctttcaagattaGCTGGatgtatcct tttattTACGCTAAAATATGAACTGTatgcttaaaatcattaccacatcatttgatgt g" /listShort="S557, murE, S558, mraY, murD, spoVE, S559, murG, murB, divIB, ylxW, ylxX, sbp, S560, ftsA, ftsZ" /listLong="S561, bpr" /label="promotor_-10" S_feature 1586241..1586329 /Source="Nicolas_S_feature" /locus_tag="new_1586241_1586329" /HighExp="G180, G150, LBGexp, Paraq, G135, Oxctl, C30, dia0, Cold, MG 15" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, Sig-" /TUshortPSig="1, 0.436" /TUlongSig="SigEF" /TUlongPSig=1 /label="S557" upshifts 1586241 /Source="Nicolas_upshifts" /id="U1267" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.834165834165834" /psig=1 /xcortree=2534 /SigmaFactorBS="gaaaaaatgctgatatctttcaagattaGCTGGatgtatcct tttattTACGCTAAAATATGAACTGTatgcttaaaatcattaccacatcatttgatgt g" /listShort="S557, murE, S558, mraY, murD, spoVE, S559, murG, murB, divIB, ylxW, ylxX, sbp, S560, ftsA, ftsZ" /listLong="S561, bpr" CDS 1586330..1587814 /gene="murE" /locus_tag="BSU_15180" /old_locus_tag="BSU15180" /EC_number="6.3.2.13" /function="16.13: Shape" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 8436954, 10520745, 12682299; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="UDP-N-acetylmuramoylalanyl-D-glutamate-2, 6-diaminopimelate ligase" /protein_id="NP_389401.1" /db_xref="EnsemblGenomes-Gn:BSU15180" /db_xref="EnsemblGenomes-Tr:CAB13391" /db_xref="GOA:Q03523" /db_xref="InterPro:IPR000713" /db_xref="InterPro:IPR004101" /db_xref="InterPro:IPR005761" /db_xref="InterPro:IPR013221" /db_xref="InterPro:IPR035911" /db_xref="InterPro:IPR036565" /db_xref="InterPro:IPR036615" /db_xref="SubtiList:BG10223" /db_xref="UniProtKB/Swiss-Prot:Q03523" /translation="MKLTKLLTYLTTEPSVNDSQDPEITSIEMDSREVKKGSLFVCVK GYTVDGHDFAQKAVENGAAAIVAEREVDVNVPVIIVRQSLRALSVLSDAFYGQPTKKL QLIGITGTNGKTSTTHMVDEILKKAGKRTGLIGTMYMKIGDETLPVKNTTPESVTLQK TFKKMNDKHVDTAIMEVSSHALSLGRVHGCDYDIAVFTNLTQDHLDYHKTMDEYRHAK SLLFSQLGGAFNHEHPKRAVLNADDEASAYFEKVTAAHISTYGIKNDADVMAKNISIT AQGTSFDLVTNKGTKHITMSLVGQFNVYNVLAAVATCIAAGIPFEIITEAVEELHGVR GRFELVNQQQEFPVIVDYAHTPDSLENVLETCRDMTEGKLFVVVGCGGDRDKTKRPKM AKIAVELADEPIFTSDNPRSEDPRAILRDMEAGVENAYYHSIANREQAIFFAIANAKK GDVVLIAGKGHETYQQIGNETFDFDDAEVAARAIVELNKNKTNS*" gene 1586330..1587814 /gene="murE" /locus_tag="BSU_15180" /old_locus_tag="BSU15180" S_feature 1587815..1587925 /Source="Nicolas_S_feature" /locus_tag="new_1587815_1587925" /HighExp="G180, G135, G150, C30, Oxctl, dia0, LBGexp, MG 25, Paraq, MG-0.2" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, Sig-" /TUshortPSig="1, 0.436" /TUlongSig="SigEF" /TUlongPSig=1 /label="S558" CDS 1587926..1588900 /gene="mraY" /locus_tag="BSU_15190" /old_locus_tag="BSU15190" /EC_number="2.7.8.13" /function="16.2: Construct biomass (Anabolism)" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:12682299, 15131133, 15849754, 16850406, 9592129, 24895118, 26620564, 27312048" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12682299, 15131133, 15849754, 16850406, 9592129, 24895118, 26620564, 27312048; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="phospho-N-acetylmuramoyl-pentapeptide undecaprenyl phosphate (C55P) transferase" /protein_id="NP_389402.2" /db_xref="EnsemblGenomes-Gn:BSU15190" /db_xref="EnsemblGenomes-Tr:CAB13392" /db_xref="GOA:Q03521" /db_xref="InterPro:IPR000715" /db_xref="InterPro:IPR003524" /db_xref="InterPro:IPR018480" /db_xref="SubtiList:BG10224" /db_xref="UniProtKB/Swiss-Prot:Q03521" /translation="MLEQVILFTILMGFLISVLLSPILIPFLRRLKFGQSIREEGPKS HQKKSGTPTMGGVMIILSIIVTTIVMTQKFSEISPEMVLLLFVTLGYGLLGFLDDYIK VVMKRNLGLTSKQKLIGQIIIAVVFYAVYHYYNFATDIRIPGTDLSFDLGWAYFILVL FMLVGGSNAVNLTDGLDGLLSGTAAIAFGAFAILAWNQSQYDVAIFSVAVVGAVLGFL VFNAHPAKVFMGDTGSLALGGAIVTIAILTKLEILLVIIGGVFVIETLSVILQVISFK TTGKRIFKMSPLHHHYELVGWSEWRVVVTFWAAGLLLAVLGIYIEVWL*" gene 1587926..1588900 /gene="mraY" /locus_tag="BSU_15190" /old_locus_tag="BSU15190" CDS 1588901..1590256 /gene="murD" /locus_tag="BSU_15200" /old_locus_tag="BSU15200" /EC_number="6.3.2.9" /function="16.2: Construct biomass (Anabolism)" /function="16.13: Shape" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 1765076, 9218784, 10966819; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="UDP-N-acetylmuramoylalanyl-D-glutamate ligase" /protein_id="NP_389403.1" /db_xref="EnsemblGenomes-Gn:BSU15200" /db_xref="EnsemblGenomes-Tr:CAB13393" /db_xref="GOA:Q03522" /db_xref="InterPro:IPR004101" /db_xref="InterPro:IPR005762" /db_xref="InterPro:IPR013221" /db_xref="InterPro:IPR036565" /db_xref="InterPro:IPR036615" /db_xref="SubtiList:BG10225" /db_xref="UniProtKB/Swiss-Prot:Q03522" /translation="MENDQFLQKQHFLILGLAKSGYAAASILHEKGIYVAVNDQKPFE ENEPAQKLSEKGIEVVCGEHPVSLFDQHQITILIKNPGIPYENIMVQEAEKRGIPVWT EIELAYYLTSAKFIGITGSNGKTTTTTLIYEMLKADSQKALIAGNIGTVASEVAYHAD GDEWIVTELSSFQLMGTHAFRPEISLILNVFDAHLDYHHTRENYEKAKQKVYLHQTAS DKAIVNQDDETVVRLAEAGKAEIVPFSVSKTLEQGAYVKDSMIMFNGEAILPLEEVVL PGAHNLENILAAIAVVKTAGASNEAVKKVLTSFTGVKHRLQYVTTVNGRKFYNDSKAT NILATSKALSAFDKPVILLAGGLDRGNGFDDLKPYMKHVKAVLTFGQTAPKLEKLGNE LGIQHVKRVDNVEQAVSAAFALSNEGDVILLSPACASWDQFKTFEERGDMFIDAVHML K*" gene 1588901..1590256 /gene="murD" /locus_tag="BSU_15200" /old_locus_tag="BSU15200" promotor_-35 1590080..1590085 /Source="Nicolas_upshift_promotors" /id="U1268" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp="0.56943056943057" /psig="0.56943056943057" /xcortree=675 /SigmaFactorBS="caaaactcgagaaactcggcaatgaactgGGAATAcaacatg tcaaacgtGTCGATAATGTTGAACAAGcagtatctgcggcgtttgcgctctcaaatga a" /listShort="spoVE, S559, murG, murB, divIB, ylxW, ylxX, sbp" /listLong="S560, ftsA, ftsZ" /label="promotor_-35" promotor_-10 1590101..1590119 /Source="Nicolas_upshift_promotors" /id="U1268" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp="0.56943056943057" /psig="0.56943056943057" /xcortree=675 /SigmaFactorBS="caaaactcgagaaactcggcaatgaactgGGAATAcaacatg tcaaacgtGTCGATAATGTTGAACAAGcagtatctgcggcgtttgcgctctcaaatga a" /listShort="spoVE, S559, murG, murB, divIB, ylxW, ylxX, sbp" /listLong="S560, ftsA, ftsZ" /label="promotor_-10" upshifts 1590111 /Source="Nicolas_upshifts" /id="U1268" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp="0.56943056943057" /psig="0.56943056943057" /xcortree=675 /SigmaFactorBS="caaaactcgagaaactcggcaatgaactgGGAATAcaacatg tcaaacgtGTCGATAATGTTGAACAAGcagtatctgcggcgtttgcgctctcaaatga a" /listShort="spoVE, S559, murG, murB, divIB, ylxW, ylxX, sbp" /listLong="S560, ftsA, ftsZ" CDS 1590317..1591417 /gene="spoVE" /locus_tag="BSU_15210" /old_locus_tag="BSU15210" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:2509435, 9622350, 15849754, 16484183, 16850406, 27312048" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 2509435, 9622350, 15849754, 16484183, 16850406, 27312048; Product type cp : cell process" /codon_start=1 /transl_table=11 /product="factor for spore cortex peptidoglycan synthesis (stage V sporulation)" /protein_id="NP_389404.1" /db_xref="EnsemblGenomes-Gn:BSU15210" /db_xref="EnsemblGenomes-Tr:CAB13394" /db_xref="GOA:P07373" /db_xref="InterPro:IPR001182" /db_xref="InterPro:IPR013437" /db_xref="InterPro:IPR013438" /db_xref="InterPro:IPR018365" /db_xref="SubtiList:BG10226" /db_xref="UniProtKB/Swiss-Prot:P07373" /translation="MTTKKTSPDLLLVIITLLLLTIGLIMVYSASAVWADYKFDDSFF FAKRQLLFAGIGVIAMFFIMNVDYWTWRTWSKLLMVICFFLLVLVLIPGVGMVRNGSR SWIGVGAFSIQPSEFMKLAMIAFLAKFLSEKQKNITSFRRGFVPALGIVFSAFLIIMC QPDLGTGTVMVGTCIVMIFVAGARIAHFVFLGLIGLSGFVGLVLSAPYRIKRITSYLN PWEDPLGSGFQIIQSLYAVGPGGLFGMGLGQSRQKFFYLPEPQTDFIFAILSEELGFI GGTLILLLFSVLLWRGIRIALGAPDLYGSFVAVGIISMIAIQVMINIGVVTGLIPVTG ITLPFLSYGGSSLTLMLMAVGVLLNVSRYSRY*" gene 1590317..1591417 /gene="spoVE" /locus_tag="BSU_15210" /old_locus_tag="BSU15210" S_feature 1591418..1591539 /Source="Nicolas_S_feature" /locus_tag="new_1591418_1591539" /HighExp="G180, C30, G135, G150, Oxctl, Paraq, LBGexp, dia0, S3, H2O2" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigEF, SigA, Sig-" /TUshortPSig="0.569, 1, 0.436" /TUlongSig="NA" /TUlongPSig="NA" /label="S559" CDS 1591540..1592631 /gene="murG" /locus_tag="BSU_15220" /old_locus_tag="BSU15220" /EC_number="2.4.1.227" /function="16.13: Shape" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:9244290, 11042447, 12538870, 12682299, 12813070" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9244290, 11042447, 12538870, 12682299, 12813070; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="UDP-N-acetylglucosamine-N-acetylmuramyl- (pentapeptide)pyrophosphoryl-undecaprenol N-acetylglucosamine transferase" /protein_id="NP_389405.2" /db_xref="EnsemblGenomes-Gn:BSU15220" /db_xref="EnsemblGenomes-Tr:CAB13395" /db_xref="GOA:P37585" /db_xref="InterPro:IPR004276" /db_xref="InterPro:IPR006009" /db_xref="InterPro:IPR007235" /db_xref="SubtiList:BG10227" /db_xref="UniProtKB/Swiss-Prot:P37585" /translation="MRIAISGGGTGGHIYPALAFIKEVQRRHPNVEFLYIGTENGLEK KIVERENIPFRSIEITGFKRKLSFENVKTVMRFLKGVKKSKSYLAEFKPDAVIGTGGY VCGPVVYAAAKMGIPTIVHEQNSLPGITNKFLSKYVNKVAICFEEAKSHFPSEKVVFT GNPRASEVVSIKTGRSLAEFGLSEDKKTVLIFGGSRGAAPINRAVIDMQDVLKTRDYQ VLYITGEVHYEKVMNELKSKGAADNMVTKPFLHQMPEYLKAIDVIVARAGATTIAEIT ALGIPSVLIPSPYVTANHQEVNARSLGQHDAAIVLKETELSGEKLIEALDRIVLNEQT LKEMSERTKSLGVPDAAARLYSVLEELKK*" gene 1591540..1592631 /gene="murG" /locus_tag="BSU_15220" /old_locus_tag="BSU15220" promotor_-35 1592020..1592029 /Source="Nicolas_upshift_promotors" /id="U1269" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1645 /SigmaFactorBS="tcacattttcctagcgagaaagttgtatttacgGGAAACCCG AgagcctctgaagTCGTCTCAATAAAGACgggacgatcattggctgaatttgggcttt c" /listShort="murB, divIB, ylxW, ylxX, sbp, S560, ftsA, ftsZ" /listLong="S561, bpr" /label="promotor_-35" promotor_-10 1592042..1592057 /Source="Nicolas_upshift_promotors" /id="U1269" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1645 /SigmaFactorBS="tcacattttcctagcgagaaagttgtatttacgGGAAACCCG AgagcctctgaagTCGTCTCAATAAAGACgggacgatcattggctgaatttgggcttt c" /listShort="murB, divIB, ylxW, ylxX, sbp, S560, ftsA, ftsZ" /listLong="S561, bpr" /label="promotor_-10" upshifts 1592047 /Source="Nicolas_upshifts" /id="U1269" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1645 /SigmaFactorBS="tcacattttcctagcgagaaagttgtatttacgGGAAACCCG AgagcctctgaagTCGTCTCAATAAAGACgggacgatcattggctgaatttgggcttt c" /listShort="murB, divIB, ylxW, ylxX, sbp, S560, ftsA, ftsZ" /listLong="S561, bpr" promotor_no_box 1592053..1592153 /Source="Nicolas_upshift_promotors" /id="U1270" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.363636363636364" /psig="0.0739260739260739" /xcortree=271 /SigmaFactorBS="aagacgggacgatcattggctgaatttgggctttctgaagac aaaaaaacggtcttaattttcggcggaagccgaggcgctgcaccgattaaccgcgctg t" /listShort="murB, divIB, ylxW, ylxX, sbp, S560, ftsA, ftsZ" /GFF_Attribute="listLong" /label="promotor_no_box" upshifts 1592113 /Source="Nicolas_upshifts" /id="U1270" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.363636363636364" /psig="0.0739260739260739" /xcortree=271 /SigmaFactorBS="aagacgggacgatcattggctgaatttgggctttctgaagac aaaaaaacggtcttaattttcggcggaagccgaggcgctgcaccgattaaccgcgctg t" /listShort="murB, divIB, ylxW, ylxX, sbp, S560, ftsA, ftsZ" /GFF_Attribute="listLong" CDS 1592663..1593574 /gene="murB" /locus_tag="BSU_15230" /old_locus_tag="BSU15230" /EC_number="1.3.1.98" /function="16.13: Shape" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 11327854, 12682299, 16484183, 22720735; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="UDP-N-acetylenolpyruvoylglucosamine reductase" /protein_id="NP_389406.1" /db_xref="EnsemblGenomes-Gn:BSU15230" /db_xref="EnsemblGenomes-Tr:CAB13396" /db_xref="GOA:P18579" /db_xref="InterPro:IPR003170" /db_xref="InterPro:IPR006094" /db_xref="InterPro:IPR011601" /db_xref="InterPro:IPR016166" /db_xref="InterPro:IPR016167" /db_xref="InterPro:IPR016169" /db_xref="InterPro:IPR036318" /db_xref="InterPro:IPR036635" /db_xref="SubtiList:BG10228" /db_xref="UniProtKB/Swiss-Prot:P18579" /translation="MEKVIQELKEREVGKVLANEPLANHTTMKIGGPADVLVIPSSVD AVKDIMDVIKKYDVKWTVIGRGSNLLVLDEGIRGVVIKLGAGLDHLELEGEQVTVGGG YSVVRLATSLSKKGLSGLEFAAGIPGSVGGAVYMNAGAHGSDMSEILVKAHILFEDGT IEWLTNEQMDFSYRTSVLQKKRPGVCLEAVLQLEQKDKESIVQQMQSNKDYRKNTQPY SSPCAGSIFRNPLPNHAGNLVEKAGLKGYQIGGAKISEMHGNFIVNAGGASAKDVLDL IDHVKKTIREKYEIDMHTEVEIIGGNR*" gene 1592663..1593574 /gene="murB" /locus_tag="BSU_15230" /old_locus_tag="BSU15230" downshifts 1593592 /Source="Nicolas_upshifts" /id="D863" /incds=0 /nref=2 /ntot=13 /MaxReadThrough="5.78428" /MaxDrop="2.8642" /score="-7.67573434" /energy="-7.4" /TU="U1267,U1268,U1269,U1270" /idTUdmin="U1266" /TUdmin=1809 /isTUend="FALSE" CDS 1593704..1594495 /gene="divIB" /locus_tag="BSU_15240" /old_locus_tag="BSU15240" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:10852898, 12682299, 15659156, 16618922, 16936019, 16936026, 20460179, 20870765" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10852898, 12682299, 15659156, 16618922, 16936019, 16936026, 20460179, 20870765; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="cell-division initiation protein" /protein_id="NP_389407.1" /db_xref="EnsemblGenomes-Gn:BSU15240" /db_xref="EnsemblGenomes-Tr:CAB13397" /db_xref="GOA:P16655" /db_xref="InterPro:IPR005548" /db_xref="InterPro:IPR013685" /db_xref="InterPro:IPR026580" /db_xref="InterPro:IPR034746" /db_xref="SubtiList:BG10229" /db_xref="UniProtKB/Swiss-Prot:P16655" /translation="MNPGQDREKIVNIEERIPKIKEQRKQKANRRLISFIMLFFIMVL IIVYLQTPISKVSTISVTGNENVSKKEIIDLSDINSGDTEFWSLDKQKTEKKIQQNKL VKKAEISKSLPNKINIAIEEYKAIAYLEKDDVYYEVLENGSVLPNEVTPDDAGPILVN WTNAKKRSQMAKQLDALSNSLKQSISEIYYTPVKMDENRIKLYMNDGYVVTASIKTFA DRMKTYPSIISQLSSNKKGIIHLEVATYFEEFGKNDKAAKKEDEN*" gene 1593704..1594495 /gene="divIB" /locus_tag="BSU_15240" /old_locus_tag="BSU15240" CDS 1594492..1595187 /gene="ylxW" /locus_tag="BSU_15250" /old_locus_tag="BSU15250" /function="16.13: Shape" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 16484183" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_389408.2" /db_xref="EnsemblGenomes-Gn:BSU15250" /db_xref="EnsemblGenomes-Tr:CAB13398" /db_xref="GOA:C0SPA3" /db_xref="InterPro:IPR010273" /db_xref="SubtiList:BG11490" /db_xref="UniProtKB/Swiss-Prot:C0SPA3" /translation="MRGKSAVLLSLIMLIAGFLISFSFQMTKENNKSAAETEEWKKEY ALRDELLKQEKENKKFEKELYQKQNKVRQAENKLKKEKSEYYNVLEDTEKYRMYIGEV GVQGEGVEVTLEDASYIPEGENVNSYIVHESHIFQVVNELYISGAAAVAVNGQRLTHD SYIKCNGPVVTVDGVQHPAPFTVSAIGDPDVLLPSLNIAGGLIDQLSMDHISVSAEKE KNVQMKPILKTKE*" gene 1594492..1595187 /gene="ylxW" /locus_tag="BSU_15250" /old_locus_tag="BSU15250" CDS 1595210..1595917 /gene="ylxX" /locus_tag="BSU_15260" /old_locus_tag="BSU15260" /function="16.13: Shape" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 16484183, 18179421" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_389409.2" /db_xref="EnsemblGenomes-Gn:BSU15260" /db_xref="EnsemblGenomes-Tr:CAB13399" /db_xref="GOA:Q45544" /db_xref="InterPro:IPR010273" /db_xref="SubtiList:BG11489" /db_xref="UniProtKB/Swiss-Prot:Q45544" /translation="MKIKRSFISISVLMVIFGLMISVQFNSLKHPKVRDTRDMWDIRE ELTSEQKKQEKLLAEINKYDKLLNSYSQTKEMTKETALNNTLQSLKKTAGMTDITGSG IVITISPLFSESLTGEPIENPPPDLLKKLINELNSYGAEHISINERRVVNHTVIRDIN GTTKIDGYALDDYPLTVKVLAKDPDMLHSRVKGSGLEDLFASENLALKAGKSESKLTL KAYDRPLDVQQLKLLKD*" gene 1595210..1595917 /gene="ylxX" /locus_tag="BSU_15260" /old_locus_tag="BSU15260" CDS 1595935..1596300 /gene="sbp" /locus_tag="BSU_15270" /old_locus_tag="BSU15270" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 1569582, 15849754, 16850406; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative integral inner membrane protein (small basic protein)" /protein_id="NP_389410.1" /db_xref="EnsemblGenomes-Gn:BSU15270" /db_xref="EnsemblGenomes-Tr:CAB13400" /db_xref="GOA:P28265" /db_xref="InterPro:IPR009709" /db_xref="SubtiList:BG10230" /db_xref="UniProtKB/Swiss-Prot:P28265" /translation="MWLPVLGLVLGIAIGLMTNLTIPSEYSNYLSLAVLAALDTLIGG IRAHLQGTYDEMVFVSGFFFNIILAISLAFLGVHLGVDLYLAGIFAFGVRLFQNIAVI RRNLLTKWTLSKKNKKNVI*" gene 1595935..1596300 /gene="sbp" /locus_tag="BSU_15270" /old_locus_tag="BSU15270" promotor_-35 1596152..1596155 /Source="Nicolas_upshift_promotors" /id="U1271" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.474525474525474" /psig="0.98901098901099" /xcortree=2335 /SigmaFactorBS="aatattatattggcaataagtttagCTTTtctgggagtccat ctTGGTGTAGACTTGTATTTAGcaggtatattcgcatttggagtcagattatttcaga a" /listShort="S560, ftsA, ftsZ" /listLong="S561, bpr" /label="promotor_-35" promotor_-10 1596171..1596190 /Source="Nicolas_upshift_promotors" /id="U1271" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.474525474525474" /psig="0.98901098901099" /xcortree=2335 /SigmaFactorBS="aatattatattggcaataagtttagCTTTtctgggagtccat ctTGGTGTAGACTTGTATTTAGcaggtatattcgcatttggagtcagattatttcaga a" /listShort="S560, ftsA, ftsZ" /listLong="S561, bpr" /label="promotor_-10" upshifts 1596187 /Source="Nicolas_upshifts" /id="U1271" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.474525474525474" /psig="0.98901098901099" /xcortree=2335 /SigmaFactorBS="aatattatattggcaataagtttagCTTTtctgggagtccat ctTGGTGTAGACTTGTATTTAGcaggtatattcgcatttggagtcagattatttcaga a" /listShort="S560, ftsA, ftsZ" /listLong="S561, bpr" S_feature 1596301..1596473 /Source="Nicolas_S_feature" /locus_tag="new_1596301_1596473" /HighExp="T3.0H, T2.30H, S2, T3.30H, Lbtran, T4.0H, T5.0H, T1.30H, S1, Lbstat" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, Sig-, SigWXY, SigA" /TUshortPSig="0.989, 0.0739, 1, 1" /TUlongSig="SigEF, Sig-" /TUlongPSig="0.569, 0.436" /label="S560" CDS 1596474..1597796 /gene="ftsA" /locus_tag="BSU_15280" /old_locus_tag="BSU15280" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:12682299, 15153768, 16159787, 16796675, 17015652, 23036588, 24224907" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12682299, 15153768, 16159787, 16796675, 17015652, 23036588, 24224907; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="cell-division protein essential for Z-ring assembly" /protein_id="NP_389411.2" /db_xref="EnsemblGenomes-Gn:BSU15280" /db_xref="EnsemblGenomes-Tr:CAB13401" /db_xref="GOA:P28264" /db_xref="InterPro:IPR003494" /db_xref="InterPro:IPR020823" /db_xref="SubtiList:BG10231" /db_xref="UniProtKB/Swiss-Prot:P28264" /translation="MNNNELYVSLDIGTSNTKVIVGEMTDDSLNIIGVGNVPSEGLKK GSIVDIDETVHSIRKAFDQAERMVGFPLRKAIVGVNGNYINIQDTNGVVAVSSENKEI QVEDVRRVMEAAQVVSVPHEQLIVDVIPKQFIVDGRDEITDPKKMLGVRLEVEGTLIT GSKTILHNLLRCVERAGIEITDICLQPLAAGSAALSKDEKNLGVALIDIGGGSTTIAV FQNGHLTSTRVIPLGGENITKDISIGLRTSTEEAERVKKQLGHAYYDEASEDEIFEVT VIGTNQKQTFTQQEAANIIEARVEEILEIVSEELRSMGITDLPGGFVLTGGQAAMPGV MSLAQDVLQNNVRVASPNYIGVRDPQYMTGVGLIQFACRNARIQGRKIGFKMPEEAIQ EIAVSSSEEQEQHHHQNEVQQRPKGKQKTQAEHNKQSKMKKLLSMFWE*" gene 1596474..1597796 /gene="ftsA" /locus_tag="BSU_15280" /old_locus_tag="BSU15280" upshifts complement(1596681) /Source="Nicolas_upshifts" /id="U1272" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.96103896103896" /psig="0.001998001998002" /xcortree=70 /SigmaFactorBS="ttgtatcttgaatattgatataatttccattaaCGCCGacaa tagcttttctAAGCGgaaaacctaccattctttcagcttggtcaaacgcttttcttat a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 complement(1596685..1596689) /Source="Nicolas_upshift_promotors" /id="U1272" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.96103896103896" /psig="0.001998001998002" /xcortree=70 /SigmaFactorBS="ttgtatcttgaatattgatataatttccattaaCGCCGacaa tagcttttctAAGCGgaaaacctaccattctttcagcttggtcaaacgcttttcttat a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 complement(1596704..1596708) /Source="Nicolas_upshift_promotors" /id="U1272" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.96103896103896" /psig="0.001998001998002" /xcortree=70 /SigmaFactorBS="ttgtatcttgaatattgatataatttccattaaCGCCGacaa tagcttttctAAGCGgaaaacctaccattctttcagcttggtcaaacgcttttcttat a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" CDS 1597832..1598980 /gene="ftsZ" /locus_tag="BSU_15290" /old_locus_tag="BSU15290" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:12682299, 12950927, 14527275, 15317782, 16159787, 16322744, 16549676, 22720735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12682299, 12950927, 14527275, 15317782, 16159787, 16322744, 16549676, 22720735; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="cell-division initiation protein" /protein_id="NP_389412.2" /db_xref="EnsemblGenomes-Gn:BSU15290" /db_xref="EnsemblGenomes-Tr:CAB13402" /db_xref="GOA:P17865" /db_xref="InterPro:IPR000158" /db_xref="InterPro:IPR003008" /db_xref="InterPro:IPR008280" /db_xref="InterPro:IPR018316" /db_xref="InterPro:IPR020805" /db_xref="InterPro:IPR024757" /db_xref="InterPro:IPR036525" /db_xref="InterPro:IPR037103" /db_xref="PDB:2RHH" /db_xref="PDB:2RHJ" /db_xref="PDB:2RHL" /db_xref="PDB:2RHO" /db_xref="PDB:2VAM" /db_xref="PDB:2VXY" /db_xref="PDB:4U39" /db_xref="SubtiList:BG10232" /db_xref="UniProtKB/Swiss-Prot:P17865" /translation="MLEFETNIDGLASIKVIGVGGGGNNAVNRMIENEVQGVEYIAVN TDAQALNLSKAEVKMQIGAKLTRGLGAGANPEVGKKAAEESKEQIEEALKGADMVFVT AGMGGGTGTGAAPVIAQIAKDLGALTVGVVTRPFTFEGRKRQLQAAGGISAMKEAVDT LIVIPNDRILEIVDKNTPMLEAFREADNVLRQGVQGISDLIATPGLINLDFADVKTIM SNKGSALMGIGIATGENRAAEAAKKAISSPLLEAAIDGAQGVLMNITGGTNLSLYEVQ EAADIVASASDQDVNMIFGSVINENLKDEIVVTVIATGFIEQEKDVTKPQRPSLNQSI KTHNQSVPKREPKREEPQQQNTVSRHTSQPADDTLDIPTFLRNRNKRG*" gene 1597832..1598980 /gene="ftsZ" /locus_tag="BSU_15290" /old_locus_tag="BSU15290" downshifts 1598954 /Source="Nicolas_upshifts" /id="D864" /incds=0 /nref=226 /ntot=389 /MaxReadThrough="2.85051" /MaxDrop="7.70428" /score="34.7919519" /energy="-13.7" /TU="U1267,U1271" /idTUdmin="U1269" /TUdmin="-5" /isTUend="TRUE" S_feature 1599179..1599282 /Source="Nicolas_S_feature" /locus_tag="new_1599179_1599282" /HighExp="T5.0H, BC, T4.0H, T3.30H, T3.0H, S2, BT, M9-stat, T2.30H, T2.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.953" /TUlongSig="SigA, SigWXY, SigA, Sig-" /TUlongPSig="0.989, 1, 1, 0.436" /label="S561" upshifts 1599179 /Source="Nicolas_upshifts" /id="U1273" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.453546453546454" /psig="0.953046953046953" /xcortree=486 /SigmaFactorBS="tttttatcattttcatatatatggaaattgaatgacatgaaa cgacaatatctgtaattcagATTGTCTACAGTTAATATACagcgatgttctgacaaac c" /listShort="S561, bpr" /GFF_Attribute="listLong" misc_feature 1599181..1599200 /Source="Nicolas_upshift_promotors" /id="U1273" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.453546453546454" /psig="0.953046953046953" /xcortree=486 /SigmaFactorBS="tttttatcattttcatatatatggaaattgaatgacatgaaa cgacaatatctgtaattcagATTGTCTACAGTTAATATACagcgatgttctgacaaac c" /listShort="S561, bpr" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" CDS 1599283..1603584 /gene="bpr" /locus_tag="BSU_15300" /old_locus_tag="BSU15300" /EC_number="3.4.21.-" /function="16.6: Maintain" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:1368833, 1938892, 2106512, 2108961, 15205417, 15375126, 18194340, 18414485, 26497454" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1368833, 1938892, 2106512, 2108961, 15205417, 15375126, 18194340, 18414485, 26497454; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="bacillopeptidase F" /protein_id="NP_389413.1" /db_xref="EnsemblGenomes-Gn:BSU15300" /db_xref="EnsemblGenomes-Tr:CAB13403" /db_xref="GOA:P16397" /db_xref="InterPro:IPR000209" /db_xref="InterPro:IPR008757" /db_xref="InterPro:IPR008969" /db_xref="InterPro:IPR008979" /db_xref="InterPro:IPR010259" /db_xref="InterPro:IPR012103" /db_xref="InterPro:IPR013320" /db_xref="InterPro:IPR013783" /db_xref="InterPro:IPR015500" /db_xref="InterPro:IPR022398" /db_xref="InterPro:IPR023828" /db_xref="InterPro:IPR033857" /db_xref="InterPro:IPR036852" /db_xref="InterPro:IPR037045" /db_xref="SubtiList:BG10233" /db_xref="UniProtKB/Swiss-Prot:P16397" /translation="MRKKTKNRLISSVLSTVVISSLLFPGAAGASSKVTSPSVKKELQ SAESIQNKISSSLKKSFKKKEKTTFLIKFKDLANPEKAAKAAVKKAKSKKLSAAKTEY QKRSAVVSSLKVTADESQQDVLKYLNTQKDKGNADQIHSYYVVNGIAVHASKEVMEKV VQFPEVEKVLPNEKRQLFKSSSPFNMKKAQKAIKATDGVEWNVDQIDAPKAWALGYDG TGTVVASIDTGVEWNHPALKEKYRGYNPENPNEPENEMNWYDAVAGEASPYDDLAHGT HVTGTMVGSEPDGTNQIGVAPGAKWIAVKAFSEDGGTDADILEAGEWVLAPKDAEGNP HPEMAPDVVNNSWGGGSGLDEWYRDMVNAWRAADIFPEFSAGNTDLFIPGGPGSIANP ANYPESFATGATDINKKLADFSLQGPSPYDEIKPEISAPGVNIRSSVPGQTYEDGWDG TSMAGPHVSAVAALLKQANASLSVDEMEDILTSTAEPLTDSTFPDSPNNGYGHGLVNA FDAVSAVTDGLGKAEGQVSVEGDDQEPPVYQHEKVTEAYEGGSLPLTLTAEDNVSVTS VKLSYKLDQGEWTEITAKRISGDHLKGTYQAEIPDIKGTKLSYKWMIHDFGGHVVSSD VYDVTVKPSITAGYKQDFETAPGGWVASGTNNNWEWGVPSTGPNTAASGEKVYGTNLT GNYANSANMNLVMPPIKAPDSGSLFLQFKSWHNLEDDFDYGYVFVLPEGEKNWEQAGV YNGKTSSWTDEEIDLSAYKGQNIQVMFNLQSDESIAKEGWYIDDVVLSDKSAGKTVKK NKLGVEKPSGKQKKKPVNPKKAKPSANTAVKHQNKAIQPQVLPLKAQVSVVETGKSTY SDQSTGQYTLKHKAGDYTLMAEAYGYQSKTQKVSLKTDQTTQANFTLEEMKKGTLKGT VINKTTGEPVTGASVYVVEDAAVEPAMTNDKGEYMLEAYEGAYTIKVAAPGYYSDEFS VELKGDVTKETALKPFVGYPGEIAYDDGTAENANSYFAAGNGWAVKMTLADGKDKGML TGGLFRFWDTEFPDPGGTEFKVEVYDATGKDGAPGKKIAGPFNAEALRNGEWTKVDLS SKGIMVDKDFYLVYIQSKPDPYSPGLAMDETGQNSGRNWQYIDGKWQPGDKADGNYMI RALVDYEAAVPEITSPTDKSYTNKDSVTVKGNASPGTTVHIYNGEKEAGETKAAADGT FHAGIILNKGENELTATASTDNGTTDASSPITVTLDQEKPELTLDNPKDGGKTNKETL TVKGAVSDDNLKDVKVNGKKATVADGSYSARILLENGRNEIKVIATDLAGNKTTKKTV IDVNFDKPVISGLIPGEDKNLKAGESVKIAFSSAEDLDATFTIRMPLTNARASVQNAT ELPLREISPGRYEGYWTATSSIKAKGAKVEVIVRDDYGNETRKTANGKLNMNTEN*" gene 1599283..1603584 /gene="bpr" /locus_tag="BSU_15300" /old_locus_tag="BSU15300" downshifts 1603581 /Source="Nicolas_upshifts" /id="D865" /incds=0 /nref=73 /ntot=169 /MaxReadThrough="0.90839" /MaxDrop="8.78054" /score="38.0577497" /energy="-11.4" /TU="NA" /idTUdmin="U1273" /TUdmin=1 /isTUend="TRUE" S_feature complement(1603592..1604734) /Source="Nicolas_S_feature" /locus_tag="new_1603592_1604734_c" /HighExp="S8, S6, S7, S5, LoTm, S4, B36, T5.0H, BT, B60" /AntisenseName="spoIIGA" /AntisenseCor="0.71080549463714104" /AntisenseRegPval="-42" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.579" /TUlongSig="NA" /TUlongPSig="NA" /label="S562" downshifts complement(1603634) /Source="Nicolas_upshifts" /id="D866" /incds=0 /nref=5 /ntot=22 /MaxReadThrough="2.36451" /MaxDrop="3.61596" /score="22.1321546" /energy="-9.6" /TU="NA" /idTUdmin="U1275" /TUdmin=0 /isTUend="TRUE" S_feature 1603712..1603778 /Source="Nicolas_S_feature" /locus_tag="new_1603712_1603778" /HighExp="M9-stat, T5.0H, S4, LoTm, T3.30H, T3.0H, B60, S3, S5, S7" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.534" /TUlongSig="NA" /TUlongPSig="NA" /label="S563" upshifts 1603714 /Source="Nicolas_upshifts" /id="U1274" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.282717282717283" /psig="0.534465534465534" /xcortree=966 /SigmaFactorBS="gcagatttccctgaaaaattgtattttcctctcaacattaat tgacagactttcccacagaGCTTGCTTTATACTTATGAAgcaagaaggggaacagcgt g" /listShort="S563, spoIIGA, sigE, S564, sigG, S565" /listLong="ylmA, NA, thiQ" misc_feature 1603715..1603734 /Source="Nicolas_upshift_promotors" /id="U1274" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.282717282717283" /psig="0.534465534465534" /xcortree=966 /SigmaFactorBS="gcagatttccctgaaaaattgtattttcctctcaacattaat tgacagactttcccacagaGCTTGCTTTATACTTATGAAgcaagaaggggaacagcgt g" /listShort="S563, spoIIGA, sigE, S564, sigG, S565" /listLong="ylmA, NA, thiQ" /label="promotor_single_box" /note="Geneious type: promotor_single_box" misc_feature complement(1603732..1603744) /Source="Nicolas_upshift_promotors" /id="U1275" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.430569430569431" /psig="0.185814185814186" /xcortree=1053 /SigmaFactorBS="caaatgacatctaaatagattttcacatctgactcctttctt tcttgcctcacgctgttcCCCTTCTTGCTTCataagtataaagcaagctctgtgggaa a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(1603744) /Source="Nicolas_upshifts" /id="U1275" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.430569430569431" /psig="0.185814185814186" /xcortree=1053 /SigmaFactorBS="caaatgacatctaaatagattttcacatctgactcctttctt tcttgcctcacgctgttcCCCTTCTTGCTTCataagtataaagcaagctctgtgggaa a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" CDS 1603779..1604708 /gene="spoIIGA" /locus_tag="BSU_15310" /old_locus_tag="BSU15310" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:7585939, 7729420, 9573195, 9663680, 10498732, 15849754, 16850406, 18378688, 21362630, 22111992" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7585939, 7729420, 9573195, 9663680, 10498732, 15849754, 16850406, 18378688, 21362630, 22111992; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="protease processing pro-sigma-E" /protein_id="NP_389414.1" /db_xref="EnsemblGenomes-Gn:BSU15310" /db_xref="EnsemblGenomes-Tr:CAB13405" /db_xref="GOA:P13801" /db_xref="InterPro:IPR005081" /db_xref="SubtiList:BG10234" /db_xref="UniProtKB/Swiss-Prot:P13801" /translation="MKIYLDVIWLLNFCFDALLLLLTAFILKRHVKKRRLVGGAFIGS SIVLLMFTPFSPIVEHPAGKLAFSVVIVVVTFGFKRFRFFFQNLFSFYFATFLMGGGI IGAHSLLQSNSIVQNGVMITNQTGFGDPISWLFIVGGFPALWFFSKRRIEDIETKNIQ YEERVSVQADLGSQTLHVRGLIDSGNQLYDPLTKTPVMIIYIDKLEPIFGTAETMIIR NTDPLEAIEQLDDSFRFLDKMRLIPYRGVGQQNQFLLCVKPDHVTIMTKEEMISADKC LIGISTTKLSADGEFDAIIHPKMLSGKAVKHVS*" gene 1603779..1604708 /gene="spoIIGA" /locus_tag="BSU_15310" /old_locus_tag="BSU15310" promotor_-10 complement(1604723..1604742) /Source="Nicolas_upshift_promotors" /id="U1276" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.494505494505495" /psig="0.57942057942058" /xcortree=1054 /SigmaFactorBS="gtcaaccgtaatttcagttttttcatcttcctctccCTTCta aatgtcacgccgTTTGAGTATGATAAGTAACGgacatttgcgaacattatgaaacgtg t" /listShort="S562" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1604736) /Source="Nicolas_upshifts" /id="U1276" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.494505494505495" /psig="0.57942057942058" /xcortree=1054 /SigmaFactorBS="gtcaaccgtaatttcagttttttcatcttcctctccCTTCta aatgtcacgccgTTTGAGTATGATAAGTAACGgacatttgcgaacattatgaaacgtg t" /listShort="S562" /GFF_Attribute="listLong" promotor_-35 complement(1604757..1604760) /Source="Nicolas_upshift_promotors" /id="U1276" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.494505494505495" /psig="0.57942057942058" /xcortree=1054 /SigmaFactorBS="gtcaaccgtaatttcagttttttcatcttcctctccCTTCta aatgtcacgccgTTTGAGTATGATAAGTAACGgacatttgcgaacattatgaaacgtg t" /listShort="S562" /GFF_Attribute="listLong" /label="promotor_-35" CDS 1604771..1605490 /gene="sigE" /locus_tag="BSU_15320" /old_locus_tag="BSU15320" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:1581961, 7708009, 8464402, 15187183, 20802044" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1581961, 7708009, 8464402, 15187183, 20802044; Product type f: factor" /codon_start=1 /transl_table=11 /product="RNA polymerase sporulation-specific sigma-29 factor (sigma-E)" /protein_id="NP_389415.2" /db_xref="EnsemblGenomes-Gn:BSU15320" /db_xref="EnsemblGenomes-Tr:CAB13406" /db_xref="GOA:P06222" /db_xref="InterPro:IPR000943" /db_xref="InterPro:IPR007627" /db_xref="InterPro:IPR007630" /db_xref="InterPro:IPR013324" /db_xref="InterPro:IPR013325" /db_xref="InterPro:IPR014200" /db_xref="InterPro:IPR014284" /db_xref="SubtiList:BG10235" /db_xref="UniProtKB/Swiss-Prot:P06222" /translation="MKKLKLRLTHLWYKLLMKLGLKSDEVYYIGGSEALPPPLSKDEE QVLLMKLPNGDQAARAILIERNLRLVVYIARKFENTGINIEDLISIGTIGLIKAVNTF NPEKKIKLATYASRCIENEILMYLRRNNKIRSEVSFDEPLNIDWDGNELLLSDVLGTD DDIITKDIEANVDKKLLKKALEQLNEREKQIMELRFGLVGEEEKTQKDVADMMGISQS YISRLEKRIIKRLRKEFNKMV*" gene 1604771..1605490 /gene="sigE" /locus_tag="BSU_15320" /old_locus_tag="BSU15320" S_feature 1605491..1605580 /Source="Nicolas_S_feature" /locus_tag="new_1605491_1605580" /HighExp="T5.0H, S3, M9-stat, T4.0H, S4, LoTm, S2, B60, B36, T3.30H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.534" /TUlongSig="NA" /TUlongPSig="NA" /label="S564" promotor_-35 1605564..1605570 /Source="Nicolas_upshift_promotors" /id="U1277" /multdbtbs="SigF,SigG" /comp="M8" /sig="SigGF" /pcomp="0.923076923076923" /psig="0.923076923076923" /xcortree=1135 /SigmaFactorBS="cagggatttcctgatttcgacagtttttcggtctgagtgcag TGCATATttttcccacccaaGGAGATACTTAAcgttgtacagcagctcctgtagggag g" /listShort="sigG" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 1605582 /Source="Nicolas_upshifts" /id="U1277" /multdbtbs="SigF,SigG" /comp="M8" /sig="SigGF" /pcomp="0.923076923076923" /psig="0.923076923076923" /xcortree=1135 /SigmaFactorBS="cagggatttcctgatttcgacagtttttcggtctgagtgcag TGCATATttttcccacccaaGGAGATACTTAAcgttgtacagcagctcctgtagggag g" /listShort="sigG" /GFF_Attribute="listLong" promotor_-10 1605584..1605595 /Source="Nicolas_upshift_promotors" /id="U1277" /multdbtbs="SigF,SigG" /comp="M8" /sig="SigGF" /pcomp="0.923076923076923" /psig="0.923076923076923" /xcortree=1135 /SigmaFactorBS="cagggatttcctgatttcgacagtttttcggtctgagtgcag TGCATATttttcccacccaaGGAGATACTTAAcgttgtacagcagctcctgtagggag g" /listShort="sigG" /GFF_Attribute="listLong" /label="promotor_-10" CDS 1605630..1606412 /gene="sigG" /locus_tag="BSU_15330" /old_locus_tag="BSU15330" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:15187183, 15256570, 16166546, 16497325, 17015665, 21935351" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15187183, 15256570, 16166546, 16497325, 17015665, 21935351; Product type f : factor" /codon_start=1 /transl_table=11 /product="RNA polymerase sporulation-specific sigma factor(sigma-G)" /protein_id="NP_389416.1" /db_xref="EnsemblGenomes-Gn:BSU15330" /db_xref="EnsemblGenomes-Tr:CAB13407" /db_xref="GOA:P19940" /db_xref="InterPro:IPR000943" /db_xref="InterPro:IPR007624" /db_xref="InterPro:IPR007627" /db_xref="InterPro:IPR007630" /db_xref="InterPro:IPR013324" /db_xref="InterPro:IPR013325" /db_xref="InterPro:IPR014212" /db_xref="InterPro:IPR014284" /db_xref="InterPro:IPR014322" /db_xref="InterPro:IPR036388" /db_xref="SubtiList:BG10236" /db_xref="UniProtKB/Swiss-Prot:P19940" /translation="MSRNKVEICGVDTSKLPVLKNEEMRKLFRQLQDEGDDSAREKLV NGNLRLVLSVIQRFNNRGEYVDDLFQVGCIGLMKSIDNFDLSHNVKFSTYAVPMIIGE IRRYLRDNNPIRVSRSLRDIAYKALQVRERLISETSKEPTAEDIAKVLEVPHEEIVFA LDAIQDPVSLFEPIYNDGGDPIYVMDQISDERNTDSQWIEELALKEGMRRLNDREKMI LRKRFFQGKTQMEVAEEIGISQAQVSRLEKAAIKQMNKNIHQ*" gene 1605630..1606412 /gene="sigG" /locus_tag="BSU_15330" /old_locus_tag="BSU15330" S_feature 1606413..1606501 /Source="Nicolas_S_feature" /locus_tag="new_1606413_1606501" /HighExp="LoTm, S7, S8, BT, S6, S4, G/S, S3, S2, S5" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.534" /TUlongSig="NA" /TUlongPSig="NA" /label="S565" promotor_-35 1606466..1606473 /Source="Nicolas_upshift_promotors" /id="U1278" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.323676323676324" /psig="0.98901098901099" /xcortree=2908 /SigmaFactorBS="aggcttttctattgattatggatGGTTTACGttttggaaaaa gTAAGGTATCCTAGTTCGTACaaagttttatgaaaattaaaacaattataaaaggcaa t" /listShort="ylmA, NA, thiQ, ylmC, S566, ylmD, ylmE, sepF, ylmG, ylmH, S567, divIVA, NA, ileS" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1606486..1606505 /Source="Nicolas_upshift_promotors" /id="U1278" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.323676323676324" /psig="0.98901098901099" /xcortree=2908 /SigmaFactorBS="aggcttttctattgattatggatGGTTTACGttttggaaaaa gTAAGGTATCCTAGTTCGTACaaagttttatgaaaattaaaacaattataaaaggcaa t" /listShort="ylmA, NA, thiQ, ylmC, S566, ylmD, ylmE, sepF, ylmG, ylmH, S567, divIVA, NA, ileS" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1606503 /Source="Nicolas_upshifts" /id="U1278" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.323676323676324" /psig="0.98901098901099" /xcortree=2908 /SigmaFactorBS="aggcttttctattgattatggatGGTTTACGttttggaaaaa gTAAGGTATCCTAGTTCGTACaaagttttatgaaaattaaaacaattataaaaggcaa t" /listShort="ylmA, NA, thiQ, ylmC, S566, ylmD, ylmE, sepF, ylmG, ylmH, S567, divIVA, NA, ileS" /GFF_Attribute="listLong" CDS 1606560..1607354 /gene="ylmA" /locus_tag="BSU_15340" /old_locus_tag="BSU15340" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 16707683, 18083814; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative ABC transporter (ATP-binding protein)" /protein_id="NP_389417.2" /db_xref="EnsemblGenomes-Gn:BSU15340" /db_xref="EnsemblGenomes-Tr:CAB13408" /db_xref="GOA:O31723" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR017871" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG13370" /db_xref="UniProtKB/Swiss-Prot:O31723" /translation="MILQLDNVSLKRNGKWILKDIHWKVEEKENWVLYGLNGAGKTAL LNMLCSYYFPTSGEMQVLGHEFGKTELGEKLRRKIGLVSAALQQKLYPADSAFEIALS GAYASIGLYETPSKETREKAIGLLEDLGAIEYADRRYETLSQGEKQRALIARALMADP ELLILDEPVTGLDFIAREKLLDTITYIANKENAPSILYVTHHAEEILPVFDKALLLKQ GEVFGSGEIKEMLTDQILSAFFDTPIHVLWNQDRPFLTRAEPITNA*" gene 1606560..1607354 /gene="ylmA" /locus_tag="BSU_15340" /old_locus_tag="BSU15340" promotor_-35 1607272..1607275 /Source="Nicolas_upshift_promotors" /id="U1279" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.9000999000999" /psig="0.976023976023976" /xcortree=567 /SigmaFactorBS="ataaaggaaatgcttactgatcaaatactttccgCTTTtttt gatacgccaaTCCATGTATTATGGAATCAGgatcggccgtttttaacaagagctgagc c" /listShort="NA, thiQ, ylmC, S566" /listLong="ylmD, ylmE, sepF, ylmG, ylmH, S567, divIVA, NA, ileS" /label="promotor_-35" promotor_-10 1607290..1607309 /Source="Nicolas_upshift_promotors" /id="U1279" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.9000999000999" /psig="0.976023976023976" /xcortree=567 /SigmaFactorBS="ataaaggaaatgcttactgatcaaatactttccgCTTTtttt gatacgccaaTCCATGTATTATGGAATCAGgatcggccgtttttaacaagagctgagc c" /listShort="NA, thiQ, ylmC, S566" /listLong="ylmD, ylmE, sepF, ylmG, ylmH, S567, divIVA, NA, ileS" /label="promotor_-10" upshifts 1607298 /Source="Nicolas_upshifts" /id="U1279" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.9000999000999" /psig="0.976023976023976" /xcortree=567 /SigmaFactorBS="ataaaggaaatgcttactgatcaaatactttccgCTTTtttt gatacgccaaTCCATGTATTATGGAATCAGgatcggccgtttttaacaagagctgagc c" /listShort="NA, thiQ, ylmC, S566" /listLong="ylmD, ylmE, sepF, ylmG, ylmH, S567, divIVA, NA, ileS" misc_RNA 1607367..1607468 /gene="tswE" /locus_tag="BSU_misc_RNA_24" /product="thiamine pyrophosphate riboswitch" /note="Evidence 1c: Function from experimental evidences in the studied genus; PubMedId: 11470904, 12410317, 15862294, 16728979, 16962976, 17307816, 18179415, 18776013; Product type n: RNA" /function="16.3: Control" gene 1607367..1607468 /gene="tswE" /locus_tag="BSU_misc_RNA_24" downshifts 1607455 /Source="Nicolas_upshifts" /id="D867" /incds=0 /nref=7 /ntot=53 /MaxReadThrough="5.58534" /MaxDrop="4.3688" /score="-2.39598083" /energy="-7.1" /TU="U1278,U1279" /idTUdmin="U1274" /TUdmin=971 /isTUend="FALSE" CDS 1607556..1608836 /gene="thiQ" /locus_tag="BSU_15350" /old_locus_tag="BSU15350" /EC_number="3.5.1.-" /function="16.3: Control" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:17618314" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 17618314; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="N-formyl-4-amino-5-aminomethyl-2- methylpyrimidinedeformylase" /protein_id="NP_389418.2" /db_xref="EnsemblGenomes-Gn:BSU15350" /db_xref="EnsemblGenomes-Tr:CAB13409" /db_xref="GOA:O31724" /db_xref="InterPro:IPR002933" /db_xref="InterPro:IPR010182" /db_xref="InterPro:IPR011650" /db_xref="InterPro:IPR036264" /db_xref="SubtiList:BG13371" /db_xref="UniProtKB/Swiss-Prot:O31724" /translation="MDQQIYSLQKKVEEHKEELIQLAKTLISYQTPAPPARNTEGIQS WIAGYLNELGFSIDKWDVYPGDPNVVGKLKGTDSADYYSLIINGHVDVAEVKEDEEWK HDPFHPIEKNGLLIGRGASDMKGGMACVLFAVKLIREASIELPGDLILQSVIGEEVGE AGTLECCKRGYHADFAIVADTSDMHIQGQGGVITGWIEIKSSQTFHDGTRRNMIHAGG GTFGASAIEKMAKIIAGLGELERHWSIMKSYPGFKPGTNTINPAVIEGGRHAAFIADE CRLWITVHFYPNETHDQVAAEIEDYVNRLSDSDIWLRENRPVFKWGGSSMIEDRGEIF PALEVDPGHPGVLALTASHQKVKRECPIIDVSQSVTDGGWLYDAGIPCVIYGPGDLHN AHSVNEKVSIEQLVEYTKIILDFIISWCSRKKEQ*" gene 1607556..1608836 /gene="thiQ" /locus_tag="BSU_15350" /old_locus_tag="BSU15350" misc_feature complement(1608777..1608793) /Source="Nicolas_upshift_promotors" /id="U1280" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.407592407592408" /psig="0.715284715284715" /xcortree=1716 /SigmaFactorBS="ttcatgtcattgttcttttttccggctgcaccagctgatgat aaaatcgAGTATAATTTTTGTATActctactagctgctcaatcgataccttctcgttc a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(1608782) /Source="Nicolas_upshifts" /id="U1280" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.407592407592408" /psig="0.715284715284715" /xcortree=1716 /SigmaFactorBS="ttcatgtcattgttcttttttccggctgcaccagctgatgat aaaatcgAGTATAATTTTTGTATActctactagctgctcaatcgataccttctcgttc a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 1608857..1608862 /Source="Nicolas_upshift_promotors" /id="U1281" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=1082 /SigmaFactorBS="aaaaaagaacaatgacatgaaaatttcttcttgctGACAAGg ttcagcctgcccgtTCATATACTTGAACAAAAGgacggaaaaaggacgtgatggaatg a" /listShort="ylmC, S566, ylmD, ylmE, sepF, ylmG, ylmH, S567, divIVA" /listLong="NA, ileS" /label="promotor_-35" promotor_-10 1608878..1608896 /Source="Nicolas_upshift_promotors" /id="U1281" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=1082 /SigmaFactorBS="aaaaaagaacaatgacatgaaaatttcttcttgctGACAAGg ttcagcctgcccgtTCATATACTTGAACAAAAGgacggaaaaaggacgtgatggaatg a" /listShort="ylmC, S566, ylmD, ylmE, sepF, ylmG, ylmH, S567, divIVA" /listLong="NA, ileS" /label="promotor_-10" upshifts 1608882 /Source="Nicolas_upshifts" /id="U1281" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=1082 /SigmaFactorBS="aaaaaagaacaatgacatgaaaatttcttcttgctGACAAGg ttcagcctgcccgtTCATATACTTGAACAAAAGgacggaaaaaggacgtgatggaatg a" /listShort="ylmC, S566, ylmD, ylmE, sepF, ylmG, ylmH, S567, divIVA" /listLong="NA, ileS" CDS 1608919..1609164 /gene="ylmC" /locus_tag="BSU_15360" /old_locus_tag="BSU15360" /experiment="publication(s) with functional evidences, PMID:12429060, 23396918" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12429060, 23396918; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="essential sporulation protein" /protein_id="NP_389419.1" /db_xref="EnsemblGenomes-Gn:BSU15360" /db_xref="EnsemblGenomes-Tr:CAB13410" /db_xref="InterPro:IPR011033" /db_xref="InterPro:IPR014238" /db_xref="InterPro:IPR027275" /db_xref="SubtiList:BG13372" /db_xref="UniProtKB/Swiss-Prot:O31725" /translation="MISISEFQVKDVVNVSNGKKLGSIGDIDINVTTGKIQAIILGGN GKVLGFFGKEEELVIPWRNIVKIGEDVILVRLSEPHA*" gene 1608919..1609164 /gene="ylmC" /locus_tag="BSU_15360" /old_locus_tag="BSU15360" promotor_-35 1609080..1609088 /Source="Nicolas_upshift_promotors" /id="U1282" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp=1 /psig=1 /xcortree=534 /SigmaFactorBS="aaatgggaaagttctcggattttttggaaaagaAGAGGAATT ggtcattccaTGGCGAAATATAGTAAAAAtcggggaagatgtaatcttagtccgatta a" /listShort="S566, ylmD, ylmE, sepF, ylmG, ylmH, S567, divIVA, NA, ileS" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1609099..1609117 /Source="Nicolas_upshift_promotors" /id="U1282" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp=1 /psig=1 /xcortree=534 /SigmaFactorBS="aaatgggaaagttctcggattttttggaaaagaAGAGGAATT ggtcattccaTGGCGAAATATAGTAAAAAtcggggaagatgtaatcttagtccgatta a" /listShort="S566, ylmD, ylmE, sepF, ylmG, ylmH, S567, divIVA, NA, ileS" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1609107 /Source="Nicolas_upshifts" /id="U1282" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp=1 /psig=1 /xcortree=534 /SigmaFactorBS="aaatgggaaagttctcggattttttggaaaagaAGAGGAATT ggtcattccaTGGCGAAATATAGTAAAAAtcggggaagatgtaatcttagtccgatta a" /listShort="S566, ylmD, ylmE, sepF, ylmG, ylmH, S567, divIVA, NA, ileS" /GFF_Attribute="listLong" S_feature 1609165..1609275 /Source="Nicolas_S_feature" /locus_tag="new_1609165_1609275" /HighExp="T3.0H, S2, S1, T4.0H, T3.30H, T5.0H, T2.0H, BC, Gly, S3" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.34150000000000003" /TUshortSig="SigH, SigEF, SigA, SigA" /TUshortPSig="1, 0.998, 0.976, 0.989" /TUlongSig="NA" /TUlongPSig="NA" /label="S566" misc_feature 1609267..1609286 /Source="Nicolas_upshift_promotors" /id="U1283" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.884115884115884" /psig=1 /xcortree=2210 /SigmaFactorBS="cacatttcatttagaaatatgcaaatcggcgctcaacgaatg cagtaagaTGTGGTAAAATAAGTGGGAAattccgcttttttaaatgtttgtcgaaagg t" /listShort="ylmD, ylmE, sepF, ylmG, ylmH, S567, divIVA, NA, ileS" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 1609277 /Source="Nicolas_upshifts" /id="U1283" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.884115884115884" /psig=1 /xcortree=2210 /SigmaFactorBS="cacatttcatttagaaatatgcaaatcggcgctcaacgaatg cagtaagaTGTGGTAAAATAAGTGGGAAattccgcttttttaaatgtttgtcgaaagg t" /listShort="ylmD, ylmE, sepF, ylmG, ylmH, S567, divIVA, NA, ileS" /GFF_Attribute="listLong" CDS 1609327..1610163 /gene="ylmD" /locus_tag="BSU_15370" /old_locus_tag="BSU15370" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 16498617, 19737354; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="conserved protein with laccase domain" /protein_id="NP_389420.1" /db_xref="EnsemblGenomes-Gn:BSU15370" /db_xref="EnsemblGenomes-Tr:CAB13411" /db_xref="GOA:O31726" /db_xref="InterPro:IPR003730" /db_xref="InterPro:IPR011324" /db_xref="SubtiList:BG13373" /db_xref="UniProtKB/Swiss-Prot:O31726" /translation="MNTYHPFSLTTPSTLMIQDWAQTNQNNKEVIAGFTTKNGGVSQK PFESLNTGLHVHDKDADVVKNREYIADMFNTDLQSWVFADQTHDNRVQKVTQRDRGKG AREYHTALKATDGIYTNEKNVFLALCFADCVPLFFYDPVKSLVGVAHAGWKGTVKQIG REMVKQWTEKEGSNPSDIYAVIGPSISGACYTVDDRVMDAVRALPVSADLAANQTAKA QYQLDLKELNRLILMDSGLASEQISVSGLCTESEPSLFYSHRRDQGKTGRMMSFIGMK EA*" gene 1609327..1610163 /gene="ylmD" /locus_tag="BSU_15370" /old_locus_tag="BSU15370" CDS 1610170..1610862 /gene="ylmE" /locus_tag="BSU_15380" /old_locus_tag="BSU15380" /function="16.13: Shape" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 14526035, 24097949; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative PLP-containing enzyme" /protein_id="NP_389421.1" /db_xref="EnsemblGenomes-Gn:BSU15380" /db_xref="EnsemblGenomes-Tr:CAB13412" /db_xref="GOA:O31727" /db_xref="InterPro:IPR001608" /db_xref="InterPro:IPR011078" /db_xref="InterPro:IPR029066" /db_xref="SubtiList:BG13374" /db_xref="UniProtKB/Swiss-Prot:O31727" /translation="MRVVDNLRHINERINEACNRSGRSSDEVTVIAVTKYVSPERAQE AVDAGITCLGENRDAELLRKQELMKGNPEWHFIGSLQSRKAKSVVNSVSYIHSLDRLS LAKEIEKRAEGTVRCFVQVNTSLEPSKHGMKKEEVIPFIQELSGFEHILVAGLMTMAP LTDDQDQIRSCFRSLRELRDQVQKLNQPNAPCTELSMGMSNDFEIAIEEGATYIRIGS SLVGNETGGVQQ*" gene 1610170..1610862 /gene="ylmE" /locus_tag="BSU_15380" /old_locus_tag="BSU15380" CDS 1610859..1611314 /gene="sepF" /locus_tag="BSU_15390" /old_locus_tag="BSU15390" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:14526035, 16420366, 16796675, 18782755, 22912848, 24218584" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 14526035, 16420366, 16796675, 18782755, 22912848, 24218584; Product type cp : cell process" /codon_start=1 /transl_table=11 /product="cell division machinery factor" /protein_id="NP_389422.3" /db_xref="EnsemblGenomes-Gn:BSU15390" /db_xref="EnsemblGenomes-Tr:CAB13413" /db_xref="GOA:O31728" /db_xref="InterPro:IPR007561" /db_xref="InterPro:IPR023052" /db_xref="PDB:3ZIH" /db_xref="PDB:3ZII" /db_xref="SubtiList:BG13375" /db_xref="UniProtKB/Swiss-Prot:O31728" /translation="MSMKNKLKNFFSMEDEEYEYEYIETERESHEEHEQKEKPAYNGN KPAGKQNVVSLQSVQKSSKVVLSEPRVYAEAQEIADHLKNRRAVVVNLQRIQHDQAKR IVDFLSGTVYAIGGDIQRIGSDIFLCTPDNVDVSGTISELISEDEHQRW*" gene 1610859..1611314 /gene="sepF" /locus_tag="BSU_15390" /old_locus_tag="BSU15390" CDS 1611321..1611593 /gene="ylmG" /locus_tag="BSU_15400" /old_locus_tag="BSU15400" /function="16.13: Shape" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 14526035, 19966467, 20359373; Product type f: factor" /codon_start=1 /transl_table=11 /product="factor involved in shape determination, distribution of nucleoids and osmotic tolerance" /protein_id="NP_389423.1" /db_xref="EnsemblGenomes-Gn:BSU15400" /db_xref="EnsemblGenomes-Tr:CAB13414" /db_xref="GOA:O31729" /db_xref="InterPro:IPR003425" /db_xref="SubtiList:BG13376" /db_xref="UniProtKB/Swiss-Prot:O31729" /translation="MILYQVFSVLSLLITIYSFALIIYIFMSWVPSTRETAVGRFLAS ICEPYLEPFRKIIPPIAMLDISPIVAILVLRFATTGLWGLYRMIAF*" gene 1611321..1611593 /gene="ylmG" /locus_tag="BSU_15400" /old_locus_tag="BSU15400" downshifts 1611582 /Source="Nicolas_upshifts" /id="D868" /incds=0 /nref=16 /ntot=97 /MaxReadThrough="6.19839" /MaxDrop="4.93537" /score="-6.17078585" /energy="-15.2" /TU="U1278,U1281,U1282,U1283" /idTUdmin="U1281" /TUdmin="-1452" /isTUend="FALSE" CDS 1611654..1612427 /gene="ylmH" /locus_tag="BSU_15410" /old_locus_tag="BSU15410" /function="16.13: Shape" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 10093218, 14526035, 21141807; Product type f: factor" /codon_start=1 /transl_table=11 /product="factor involved in shape determination, RNA-binding fold" /protein_id="NP_389424.1" /db_xref="EnsemblGenomes-Gn:BSU15410" /db_xref="EnsemblGenomes-Tr:CAB13415" /db_xref="GOA:P71020" /db_xref="InterPro:IPR002942" /db_xref="InterPro:IPR036986" /db_xref="SubtiList:BG11856" /db_xref="UniProtKB/Swiss-Prot:P71020" /translation="MSDIYQHFRKDERAFIDQALEWKRIVQEQYRMKLTDFLDPREQV ILSAVTGQADVGLAFSGGYDRAERKRAILFPEYITPEESDFELQAFNVRYADKFVSVD HRSLLGALMGIGLKRQKFGDIVFSETAVQLIVSADTADFVAAQLTQAGKAAVSLEKID LSDLNIPAVDVEIRDDTVSSLRLDAVCASMSRQSRQKSQTLVKNGLVKVNWKVVEDPS YIVAEGDMLSIRGFGRCSLTKIEGKTKKDKWRVTFERQK*" gene 1611654..1612427 /gene="ylmH" /locus_tag="BSU_15410" /old_locus_tag="BSU15410" promotor_-35 1612143..1612150 /Source="Nicolas_upshift_promotors" /id="U1284" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp="0.973026973026973" /psig="0.973026973026973" /xcortree=1638 /SigmaFactorBS="aatcgacttgtcagacCTTAACATtccagcagttgatGTCGA AATAAGAGATGACAcggtttcttctttaaggcttgacgccgtctgcgcctctatgagc a" /listShort="S567, divIVA, NA, ileS" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1612164..1612182 /Source="Nicolas_upshift_promotors" /id="U1284" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp="0.973026973026973" /psig="0.973026973026973" /xcortree=1638 /SigmaFactorBS="aatcgacttgtcagacCTTAACATtccagcagttgatGTCGA AATAAGAGATGACAcggtttcttctttaaggcttgacgccgtctgcgcctctatgagc a" /listShort="S567, divIVA, NA, ileS" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1612187 /Source="Nicolas_upshifts" /id="U1284" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp="0.973026973026973" /psig="0.973026973026973" /xcortree=1638 /SigmaFactorBS="aatcgacttgtcagacCTTAACATtccagcagttgatGTCGA AATAAGAGATGACAcggtttcttctttaaggcttgacgccgtctgcgcctctatgagc a" /listShort="S567, divIVA, NA, ileS" /GFF_Attribute="listLong" S_feature 1612428..1612520 /Source="Nicolas_S_feature" /locus_tag="new_1612428_1612520" /HighExp="C90, M0t90, C30, GM-0.1, Glucon, MG 5, GM 45, GM 5, GM 60, GM 120" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigD, SigA, SigH, SigEF, SigA" /TUshortPSig="0.973, 1, 1, 0.998, 0.989" /TUlongSig="SigA" /TUlongPSig="0.976" /label="S567" CDS 1612521..1613015 /gene="divIVA" /locus_tag="BSU_15420" /old_locus_tag="BSU15420" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:10724454, 12950914, 14526035, 15165232, 15554965, 16885474, 22108385, 22582279, 23264578, 24129255, 28674273" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10724454, 12950914, 14526035, 15165232, 15554965, 16885474, 22108385, 22582279, 23264578, 24129255, 28674273; Product type f : factor" /codon_start=1 /transl_table=11 /product="cell-division initiation protein" /protein_id="NP_389425.1" /db_xref="EnsemblGenomes-Gn:BSU15420" /db_xref="EnsemblGenomes-Tr:CAB13416" /db_xref="GOA:P71021" /db_xref="InterPro:IPR007793" /db_xref="InterPro:IPR019933" /db_xref="PDB:2WUJ" /db_xref="PDB:2WUK" /db_xref="SubtiList:BG11835" /db_xref="UniProtKB/Swiss-Prot:P71021" /translation="MPLTPNDIHNKTFTKSFRGYDEDEVNEFLAQVRKDYEIVLRKKT ELEAKVNELDERIGHFANIEETLNKSILVAQEAAEDVKRNSQKEAKLIVREAEKNADR IINESLSKSRKIAMEIEELKKQSKVFRTRFQMLIEAQLDLLKNDDWDHLLEYEVDAVF EEKE*" gene 1612521..1613015 /gene="divIVA" /locus_tag="BSU_15420" /old_locus_tag="BSU15420" promotor_-35 1613028..1613035 /Source="Nicolas_upshift_promotors" /id="U1285" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.556443556443556" /psig="0.999000999001" /xcortree=597 /SigmaFactorBS="tatttgaggaaaaggaataaattctctgattaTCTTGACAtt ttcttagcttgTCGAATATAATACGTTCATAaattcagatgaaaaaacggttgaaagg g" /listShort="NA, ileS" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1613049..1613068 /Source="Nicolas_upshift_promotors" /id="U1285" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.556443556443556" /psig="0.999000999001" /xcortree=597 /SigmaFactorBS="tatttgaggaaaaggaataaattctctgattaTCTTGACAtt ttcttagcttgTCGAATATAATACGTTCATAaattcagatgaaaaaacggttgaaagg g" /listShort="NA, ileS" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1613056 /Source="Nicolas_upshifts" /id="U1285" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.556443556443556" /psig="0.999000999001" /xcortree=597 /SigmaFactorBS="tatttgaggaaaaggaataaattctctgattaTCTTGACAtt ttcttagcttgTCGAATATAATACGTTCATAaattcagatgaaaaaacggttgaaagg g" /listShort="NA, ileS" /GFF_Attribute="listLong" misc_RNA 1613078..1613304 /gene="iswA" /locus_tag="BSU_misc_RNA_25" /product="T-box riboswitch specific of isoleucine tRNA" /note="Evidence 2b: Function from indirect experimental evidences (e.g. phenotypes); PubMedId: 1317842, 9098041, 12165569, 12547201; Product type n: RNA" gene 1613078..1613304 /gene="iswA" /locus_tag="BSU_misc_RNA_25" downshifts 1613271 /Source="Nicolas_upshifts" /id="D869" /incds=0 /nref=43 /ntot=100 /MaxReadThrough="7.76706" /MaxDrop="5.97038" /score="48.8352635" /energy="-19.4" /TU="U1278,U1282,U1283,U1284,U1285" /idTUdmin="U1281" /TUdmin=237 /isTUend="FALSE" CDS 1613357..1616122 /gene="ileS" /locus_tag="BSU_15430" /old_locus_tag="BSU15430" /EC_number="6.1.1.5" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 12682299, 16697013, 17043414, 17095543, 28139725; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="isoleucyl-tRNA synthetase" /protein_id="NP_389426.2" /db_xref="EnsemblGenomes-Gn:BSU15430" /db_xref="EnsemblGenomes-Tr:CAB13417" /db_xref="GOA:Q45477" /db_xref="InterPro:IPR001412" /db_xref="InterPro:IPR002300" /db_xref="InterPro:IPR002301" /db_xref="InterPro:IPR009008" /db_xref="InterPro:IPR009080" /db_xref="InterPro:IPR013155" /db_xref="InterPro:IPR014729" /db_xref="InterPro:IPR023585" /db_xref="InterPro:IPR033708" /db_xref="SubtiList:BG11792" /db_xref="UniProtKB/Swiss-Prot:Q45477" /translation="MDFKDTLLMPKTDFPMRGNLPNREPDIQKKWEEEDIYRLVQERT KDRPKFVLHDGPPYANGDIHMGHALNKILKDFIVRYKSMSGYNAPYVPGWDTHGLPIE TALTKNKKVNRKEMSVAEFRKLCEEYAWKQIEGQREQFKRLGVRGDWENPYVTLKPEY EAQQIRVFGEMAKRGYIYKGLKPVNWSPSSESALAEAEIEYQDKRSASIYVAFGVKDG KGVLENGERIIIWTTTPWTIPANLGISVHPDLEYSVIAVGEDRFVVASALVENVASAC GFDQYEVTRTVKGKDLENIIAEHPLYGRDSLVMLGEHVTTDAGTGCVHTAPGHGEDDF IIGQKYGLDVLCPVDEKGVMTSEAPGFEGMFYDDANKAITQQLDEKGALVKLEFITHS YPHDWRTKKPTIFRATAQWFASIKDFRSDLLDAIKETKWVPEWGEQRLHNMVRDRGDW CISRQRAWGVPIPVFYAENGEPVITDETIEHVSELFRQHGSNIWFEKEAKDLLPEGFT HPGSPNGTFTKEQDIMDVWFDSGSSHQAVLEERDDLVRPADLYLEGSDQYRGWFNSSL STAVAVTGKAPYKGVLSHGFALDGEGRKMSKSIGNVVVPAKVMKQLGADILRLWVSSV DYQADVRVSDAILKQVAEVYRKIRNTFRFLHGNLFDFDPKTNAVAVEDLREVDQYMLI KLNKLIDKVKKAYDEYEFAVVYHSIHNFCTIELSSFYLDFAKDIVYIEHADHPDRRSM QTVFYETLLALVKLSAPILPHTADELWSHLTFVEEQSVQLTDMPETITVPNSEATEEK FDRFMALRDDVLKALETARNEKIIGKSLEANLKLYPNKENKELLASIKENLSQLFIVS ELTISEENEAPNDAQSFATGKIAVEKAEGEMCERSRVISKDVGANPKYPTLSLRNAEI VEKYYQK*" gene 1613357..1616122 /gene="ileS" /locus_tag="BSU_15430" /old_locus_tag="BSU15430" downshifts 1616113 /Source="Nicolas_upshifts" /id="D870" /incds=0 /nref=233 /ntot=261 /MaxReadThrough="2.6695" /MaxDrop="6.91924" /score="40.2175565" /energy="-13.9" /TU="NA" /idTUdmin="U1278" /TUdmin="-1" /isTUend="TRUE" downshifts complement(1616168) /Source="Nicolas_upshifts" /id="D871" /incds=0 /nref=6 /ntot=17 /MaxReadThrough="1.29709" /MaxDrop="3.66645" /score="13.8608728" /energy="-15.6" /TU="NA" /idTUdmin="U1275" /TUdmin="-12534" /isTUend="FALSE" promotor_-35 1616203..1616209 /Source="Nicolas_upshift_promotors" /id="U1286" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=855 /SigmaFactorBS="aagagtgacatcctttagaacgaaaggaaaaatcttatgGGC TTTAgatcatcattcacaGGCAACAATAAAgatactacgttaagagcaggagttgtga a" /listShort="ylyA, lspA, rluD" /listLong="NA, pyrR, NA, pyrP, NA, pyrB, pyrC, pyrAA, pyrAB, pyrK, pyrD, pyrF, pyrE" /label="promotor_-35" promotor_-10 1616224..1616235 /Source="Nicolas_upshift_promotors" /id="U1286" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=855 /SigmaFactorBS="aagagtgacatcctttagaacgaaaggaaaaatcttatgGGC TTTAgatcatcattcacaGGCAACAATAAAgatactacgttaagagcaggagttgtga a" /listShort="ylyA, lspA, rluD" /listLong="NA, pyrR, NA, pyrP, NA, pyrB, pyrC, pyrAA, pyrAB, pyrK, pyrD, pyrF, pyrE" /label="promotor_-10" upshifts 1616224 /Source="Nicolas_upshifts" /id="U1286" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=855 /SigmaFactorBS="aagagtgacatcctttagaacgaaaggaaaaatcttatgGGC TTTAgatcatcattcacaGGCAACAATAAAgatactacgttaagagcaggagttgtga a" /listShort="ylyA, lspA, rluD" /listLong="NA, pyrR, NA, pyrP, NA, pyrB, pyrC, pyrAA, pyrAB, pyrK, pyrD, pyrF, pyrE" CDS 1616267..1616641 /gene="ylyA" /locus_tag="BSU_15440" /old_locus_tag="BSU15440" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:15496987, 23123912, 23678950" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15496987, 23123912, 23678950; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="sporulation-related RNA polymerase-binding factor" /protein_id="NP_389427.2" /db_xref="EnsemblGenomes-Gn:BSU15440" /db_xref="EnsemblGenomes-Tr:CAB13418" /db_xref="GOA:Q45478" /db_xref="InterPro:IPR000962" /db_xref="InterPro:IPR016841" /db_xref="InterPro:IPR020458" /db_xref="SubtiList:BG11795" /db_xref="UniProtKB/Swiss-Prot:Q45478" /translation="MNDQLTAIYTELLLMKEELQSRLFEYSCFQVSTSPQAAINQKQK ATLIYHIKEELQDVLLALSKIENGTFGYCEETGAPIPLAKLAVLPTARTANDFLYSVQ FEKKTLPIWKSTDIEYGQALYE*" gene 1616267..1616641 /gene="ylyA" /locus_tag="BSU_15440" /old_locus_tag="BSU15440" promotor_-35 1616673..1616677 /Source="Nicolas_upshift_promotors" /id="U1287" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.953046953046953" /psig=1 /xcortree=2549 /SigmaFactorBS="gtatgaataacagtgtctgtccggttaatatgcctgatattT CTTTactccagtgctttttATTGATAAAATGCATAATGGattaaagtaaccgtaaact g" /listShort="lspA, rluD, NA, pyrR, NA, pyrP, NA, pyrB, pyrC, pyrAA, pyrAB, pyrK, pyrD, pyrF, pyrE, S568" /listLong="NA, S569, cysH, cysP, sat, cysC, S570, sumT, sirB, sirC" /label="promotor_-35" upshifts 1616692 /Source="Nicolas_upshifts" /id="U1287" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.953046953046953" /psig=1 /xcortree=2549 /SigmaFactorBS="gtatgaataacagtgtctgtccggttaatatgcctgatattT CTTTactccagtgctttttATTGATAAAATGCATAATGGattaaagtaaccgtaaact g" /listShort="lspA, rluD, NA, pyrR, NA, pyrP, NA, pyrB, pyrC, pyrAA, pyrAB, pyrK, pyrD, pyrF, pyrE, S568" /listLong="NA, S569, cysH, cysP, sat, cysC, S570, sumT, sirB, sirC" promotor_-10 1616693..1616712 /Source="Nicolas_upshift_promotors" /id="U1287" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.953046953046953" /psig=1 /xcortree=2549 /SigmaFactorBS="gtatgaataacagtgtctgtccggttaatatgcctgatattT CTTTactccagtgctttttATTGATAAAATGCATAATGGattaaagtaaccgtaaact g" /listShort="lspA, rluD, NA, pyrR, NA, pyrP, NA, pyrB, pyrC, pyrAA, pyrAB, pyrK, pyrD, pyrF, pyrE, S568" /listLong="NA, S569, cysH, cysP, sat, cysC, S570, sumT, sirB, sirC" /label="promotor_-10" CDS 1616744..1617208 /gene="lspA" /locus_tag="BSU_15450" /old_locus_tag="BSU15450" /EC_number="3.4.23.36" /function="16.2: Construct biomass (Anabolism)" /function="16.13: Shape" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:9880550, 9882689, 10497172, 15849754, 16850406" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9880550, 9882689, 10497172, 15849754, 16850406; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="signal peptidase II" /protein_id="NP_389428.1" /db_xref="EnsemblGenomes-Gn:BSU15450" /db_xref="EnsemblGenomes-Tr:CAB13419" /db_xref="GOA:Q45479" /db_xref="InterPro:IPR001872" /db_xref="SubtiList:BG11793" /db_xref="UniProtKB/Swiss-Prot:Q45479" /translation="MLYYMIALLIIAADQLTKWLVVKNMELGQSIPIIDQVFYITSHR NTGAAWGILAGQMWFFYLITTAVIIGIVYYIQRYTKGQRLLGVALGLMLGGAIGNFID RAVRQEVVDFIHVIIVNYNYPIFNIADSSLCVGVMLLFIQMLLDSGKKKKEQ*" gene 1616744..1617208 /gene="lspA" /locus_tag="BSU_15450" /old_locus_tag="BSU15450" CDS 1617210..1618121 /gene="rluD" /locus_tag="BSU_15460" /old_locus_tag="BSU15460" /EC_number="4.2.1.-" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 15078091, 15928344, 17188032, 17937767, 18032607, 20817755; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="pseudouridylate synthase" /protein_id="NP_389429.3" /db_xref="EnsemblGenomes-Gn:BSU15460" /db_xref="EnsemblGenomes-Tr:CAB13420" /db_xref="GOA:Q45480" /db_xref="InterPro:IPR002942" /db_xref="InterPro:IPR006145" /db_xref="InterPro:IPR006224" /db_xref="InterPro:IPR006225" /db_xref="InterPro:IPR020103" /db_xref="InterPro:IPR036986" /db_xref="SubtiList:BG11796" /db_xref="UniProtKB/Swiss-Prot:Q45480" /translation="MNQIDITASEEQKSERIDKFLASTENDWSRTQVQQWVKDGQVVV NGSAVKANYKIQPGDQVTVTVPEPEALDVLAEPMDLDIYYEDQDVLVVNKPRGMVVHP APGHLTGTLVNGLMAHCTDLSGINGVMRPGIVHRIDKDTSGLLMVAKNDMAHESLVNQ LVNKTVTRKYTAVVHGLISHDDGTIDAPIGRDKKDRQSMTVTRDGKNAVTHFHVLERF QDFTLVECQLETGRTHQIRVHMKYIGFPLAGDPKYGPRKTIDFNGQALHAGVLGFDHP RTGEYVEFEAPLPEDMAELIENLRKNG*" gene 1617210..1618121 /gene="rluD" /locus_tag="BSU_15460" /old_locus_tag="BSU15460" promotor_-35 1618116..1618123 /Source="Nicolas_upshift_promotors" /id="U1288" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.785214785214785" /psig=1 /xcortree=2423 /SigmaFactorBS="ttaatcgaaaacctcagaaaaaacGGTTGACAgagggtttct tttcTGAAATAATAAACGAAGCTGaatagattctttaaaacagtccagagaggctgag a" /listShort="NA, pyrR, NA, pyrP, NA, pyrB, pyrC, pyrAA, pyrAB, pyrK, pyrD, pyrF, pyrE, S568" /listLong="NA, S569, cysH, cysP, sat, cysC, S570, sumT, sirB, sirC" /label="promotor_-35" promotor_-10 1618138..1618157 /Source="Nicolas_upshift_promotors" /id="U1288" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.785214785214785" /psig=1 /xcortree=2423 /SigmaFactorBS="ttaatcgaaaacctcagaaaaaacGGTTGACAgagggtttct tttcTGAAATAATAAACGAAGCTGaatagattctttaaaacagtccagagaggctgag a" /listShort="NA, pyrR, NA, pyrP, NA, pyrB, pyrC, pyrAA, pyrAB, pyrK, pyrD, pyrF, pyrE, S568" /listLong="NA, S569, cysH, cysP, sat, cysC, S570, sumT, sirB, sirC" /label="promotor_-10" upshifts 1618152 /Source="Nicolas_upshifts" /id="U1288" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.785214785214785" /psig=1 /xcortree=2423 /SigmaFactorBS="ttaatcgaaaacctcagaaaaaacGGTTGACAgagggtttct tttcTGAAATAATAAACGAAGCTGaatagattctttaaaacagtccagagaggctgag a" /listShort="NA, pyrR, NA, pyrP, NA, pyrB, pyrC, pyrAA, pyrAB, pyrK, pyrD, pyrF, pyrE, S568" /listLong="NA, S569, cysH, cysP, sat, cysC, S570, sumT, sirB, sirC" misc_RNA 1618161..1618277 /gene="pyaA" /locus_tag="BSU_misc_RNA_26" /product="pyrimidine biosynthesis operon attenuator" /experiment="publication(s) with functional evidences, PMID:7868607, 8206849, 8636037, 8955403, 9488732, 9932459, 11726695, 12787499, 15252202" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7868607, 8206849, 8636037, 8955403, 9488732, 9932459, 11726695, 12787499, 15252202; Product type n: RNA" gene 1618161..1618277 /gene="pyaA" /locus_tag="BSU_misc_RNA_26" CDS 1618304..1618849 /gene="pyrR" /locus_tag="BSU_15470" /old_locus_tag="BSU15470" /EC_number="2.4.2.9" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:7798145, 9932459, 12482852, 15716449, 17322189, 18678934" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7798145, 9932459, 12482852, 15716449, 17322189, 18678934; Product type r : regulator" /codon_start=1 /transl_table=11 /product="transcriptional attenuator and uracil phosphoribosyltransferase activity" /protein_id="NP_389430.1" /db_xref="EnsemblGenomes-Gn:BSU15470" /db_xref="EnsemblGenomes-Tr:CAB13421" /db_xref="GOA:P39765" /db_xref="InterPro:IPR000836" /db_xref="InterPro:IPR023050" /db_xref="InterPro:IPR029057" /db_xref="PDB:1A3C" /db_xref="PDB:1A4X" /db_xref="PDB:4P82" /db_xref="SubtiList:BG10712" /db_xref="UniProtKB/Swiss-Prot:P39765" /translation="MNQKAVILDEQAIRRALTRIAHEMIERNKGMNNCILVGIKTRGI YLAKRLAERIEQIEGNPVTVGEIDITLYRDDLSKKTSNDEPLVKGADIPVDITDQKVI LVDDVLYTGRTVRAGMDALVDVGRPSSIQLAVLVDRGHRELPIRADYIGKNIPTSKSE KVMVQLDEVDQNDLVAIYENE*" gene 1618304..1618849 /gene="pyrR" /locus_tag="BSU_15470" /old_locus_tag="BSU15470" downshifts complement(1618498) /Source="Nicolas_upshifts" /id="D872" /incds=1 /nref=1 /ntot=47 /MaxReadThrough="1.85132" /MaxDrop="2.50006" /score="0.812637138" /energy="-7" /TU="NA" /idTUdmin="U1275" /TUdmin="-14864" /isTUend="FALSE" downshifts 1618840 /Source="Nicolas_upshifts" /id="D873" /incds=0 /nref=13 /ntot=149 /MaxReadThrough="8.16191" /MaxDrop="3.4492" /score="16.3570883" /energy="-11.5" /TU="U1287,U1288" /idTUdmin="U1286" /TUdmin=704 /isTUend="FALSE" misc_RNA 1618853..1618970 /gene="pyaB" /locus_tag="BSU_misc_RNA_27" /product="pyrimidine biosynthesis operon attenuator" /experiment="publication(s) with functional evidences, PMID:7868607, 8206849, 8636037, 8955403, 9488732, 9932459, 11726695, 12787499, 15252202" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7868607, 8206849, 8636037, 8955403, 9488732, 9932459, 11726695, 12787499, 15252202; Product type n: RNA" gene 1618853..1618970 /gene="pyaB" /locus_tag="BSU_misc_RNA_27" CDS 1619023..1620330 /gene="pyrP" /locus_tag="BSU_15480" /old_locus_tag="BSU15480" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1c: Function from experimental evidences in the studied genus; PubMedId: 8206848, 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="uracil permease" /protein_id="NP_389431.2" /db_xref="EnsemblGenomes-Gn:BSU15480" /db_xref="EnsemblGenomes-Tr:CAB13422" /db_xref="GOA:P39766" /db_xref="InterPro:IPR006042" /db_xref="InterPro:IPR006043" /db_xref="InterPro:IPR029935" /db_xref="SubtiList:BG10992" /db_xref="UniProtKB/Swiss-Prot:P39766" /translation="MSKKKVNLGVRDVPTPFSWVSFSLQHLFAMFGSTILVPKLVGMS PAVALVTSGIGTLAYLLITKGQIPAYLGSSFAFISPIILVKATGGPGAAMVGAFLAGL VYGLIALLIRQLGTGWLMKILPPVVVGPVIIVIGLGLASTAVNMAMYADPNASELVYS LKHFSVAGVTLAITIICAIFLRGFLSLIPVLIGIIGGYLFALTQGIVNFQPVLDAKWF AVPEFIIPFKDYSPSVTLGIAAAMVPVAFVTMSEHIGHQMVLSKVVGQDFIKKPGLHR SIMGDSVATILASLIGGPPTTTYGENIGVLAITRVFSVFVIGGAAVIALCFGFIGKIS ALISSVPSAVMGGVSFLLFGIIASSGLRMLIDNKIDYENNRNLIITSVILVIGVGGAF IQVSQGGFQVSGMALAAIVGVILNLILPQAKEEQADTSEQHHI*" gene 1619023..1620330 /gene="pyrP" /locus_tag="BSU_15480" /old_locus_tag="BSU15480" misc_RNA 1620331..1620445 /gene="pyaC" /locus_tag="BSU_misc_RNA_28" /product="pyrimidine biosynthesis operon attenuator" /experiment="publication(s) with functional evidences, PMID:7868607, 8206849, 8636037, 8955403, 9488732, 9932459, 11726695, 12787499, 15252202" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7868607, 8206849, 8636037, 8955403, 9488732, 9932459, 11726695, 12787499, 15252202; Product type n: RNA" gene 1620331..1620445 /gene="pyaC" /locus_tag="BSU_misc_RNA_28" CDS 1620476..1621390 /gene="pyrB" /locus_tag="BSU_15490" /old_locus_tag="BSU15490" /EC_number="2.1.3.2" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:8535162, 16321950, 21663747" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8535162, 16321950, 21663747; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="aspartate carbamoyltransferase" /protein_id="NP_389432.2" /db_xref="EnsemblGenomes-Gn:BSU15490" /db_xref="EnsemblGenomes-Tr:CAB13423" /db_xref="GOA:P05654" /db_xref="InterPro:IPR002082" /db_xref="InterPro:IPR006130" /db_xref="InterPro:IPR006131" /db_xref="InterPro:IPR006132" /db_xref="InterPro:IPR036901" /db_xref="PDB:2AT2" /db_xref="PDB:3R7D" /db_xref="PDB:3R7F" /db_xref="PDB:3R7L" /db_xref="SubtiList:BG10713" /db_xref="UniProtKB/Swiss-Prot:P05654" /translation="MKHLTTMSELSTEEIKDLLQTAQELKSGKTDNQLTGKFAANLFF EPSTRTRFSFEVAEKKLGMNVLNLDGTSTSVQKGETLYDTIRTLESIGVDVCVIRHSE DEYYEELVSQVNIPILNAGDGCGQHPTQSLLDLMTIYEEFNTFKGLTVSIHGDIKHSR VARSNAEVLTRLGARVLFSGPSEWQDEENTFGTYVSMDEAVESSDVVMLLRIQNERHQ SAVSQEGYLNKYGLTVERAERMKRHAIIMHPAPVNRGVEIDDSLVESEKSRIFKQMKN GVFIRMAVIQRALQTNVKRGEAAYVISH*" gene 1620476..1621390 /gene="pyrB" /locus_tag="BSU_15490" /old_locus_tag="BSU15490" CDS 1621374..1622660 /gene="pyrC" /locus_tag="BSU_15500" /old_locus_tag="BSU15500" /EC_number="3.5.2.3" /function="2: Purines, pyrimidines, nucleosides, and nucleotides" /experiment="publication(s) with functional evidences, PMID:7516791, 16522191, 21045288" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7516791, 16522191, 21045288; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="dihydroorotase" /protein_id="NP_389433.2" /db_xref="EnsemblGenomes-Gn:BSU15500" /db_xref="EnsemblGenomes-Tr:CAB13424" /db_xref="GOA:P25995" /db_xref="InterPro:IPR002195" /db_xref="InterPro:IPR004722" /db_xref="InterPro:IPR006680" /db_xref="InterPro:IPR011059" /db_xref="InterPro:IPR032466" /db_xref="SubtiList:BG10714" /db_xref="UniProtKB/Swiss-Prot:P25995" /translation="MSYLIKNGWILNENGEKTQADIRVTGETITAIGKLDATDNETVI DAKGLLVSPGFVDLHVHFREPGGEKKETIETGAKAAARGGYTTVAAMPNTRPVPDTKE QMEWVQNRIKETSCVRVLPYASITIRQIGDEMTNFEALKEAGAFAFTDDGVGIQTAGM MYEAMKRAAAIDKAIVAHCEDNSLIYGGSVHEGTFSKANGLNGIPSVCESVHIARDVL LAEAANCHYHVCHISTKESVRVVRDAKKAGIRVTAEVSPHHLLLCDEDIPGLDTNYKM NPPLRSPEDRAALIEGLLDGTIDFIATDHAPHTEEEKNTEMKLAPFGIVGLETAFPLL YTHFVKNGSWSLKQLIDYMTIKPCEAFGLPYGTLQTGQAADITLIDLEKEAVIDKETF LSKGKNTPFNGISCTGWPVATIAAGKLAYEEGRLVK*" gene 1621374..1622660 /gene="pyrC" /locus_tag="BSU_15500" /old_locus_tag="BSU15500" CDS 1622657..1623751 /gene="pyrAA" /locus_tag="BSU_15510" /old_locus_tag="BSU15510" /EC_number="6.3.5.5" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1c: Function from experimental evidences in the studied genus; PubMedId: 1709162, 11390694, 23750951; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="pyrimidine-specific carbamoyl-phosphate synthetase (small subunit, glutaminase subunit)" /protein_id="NP_389434.1" /db_xref="EnsemblGenomes-Gn:BSU15510" /db_xref="EnsemblGenomes-Tr:CAB13425" /db_xref="GOA:P25993" /db_xref="InterPro:IPR002474" /db_xref="InterPro:IPR006274" /db_xref="InterPro:IPR017926" /db_xref="InterPro:IPR029062" /db_xref="InterPro:IPR035686" /db_xref="InterPro:IPR036480" /db_xref="SubtiList:BG10715" /db_xref="UniProtKB/Swiss-Prot:P25993" /translation="MKRRLVLENGAVFEGEAFGSLEHNMGEVVFNTGMTGYQEILSDP SYCGQIVTLTYPLIGNYGINRDDFESITPFVKGLIIKELCELPSNWRSAYTLDEYLKM KNIPGLQGIDTRKLTRMIRTAGALKGTFASSDEDIEAVLKRLNETELPRNQVSQVSAK TAYPSPGRGKRIVLVDFGMKHGILRELNKRKCDVIVVPYNITAEEVLQLKPDGIMLSN GPGDPKDVPEAIEMIKGVLGKVPLFGICLGHQLFALACGANTEKMKFGHRGSNHPVKE LATGKVALTSQNHGYTVSSISKTELEVTHIAINDDTIEGLKHKTLPAFTVQYHPEASP GPEDANHLFDRFIEMIETTEKEGEAVCQNA*" gene 1622657..1623751 /gene="pyrAA" /locus_tag="BSU_15510" /old_locus_tag="BSU15510" CDS 1623736..1626951 /gene="pyrAB" /locus_tag="BSU_15520" /old_locus_tag="BSU15520" /EC_number="6.3.5.5" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1c: Function from experimental evidences in the studied genus; PubMedId: 216664, 6120161, 10732707, 23750951; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="pyrimidine-specific carbamoyl-phosphate synthetase (large subunit)" /protein_id="NP_389435.1" /db_xref="EnsemblGenomes-Gn:BSU15520" /db_xref="EnsemblGenomes-Tr:CAB13426" /db_xref="GOA:P25994" /db_xref="InterPro:IPR005479" /db_xref="InterPro:IPR005480" /db_xref="InterPro:IPR005483" /db_xref="InterPro:IPR006275" /db_xref="InterPro:IPR011607" /db_xref="InterPro:IPR011761" /db_xref="InterPro:IPR013815" /db_xref="InterPro:IPR016185" /db_xref="InterPro:IPR033937" /db_xref="InterPro:IPR036897" /db_xref="InterPro:IPR036914" /db_xref="SubtiList:BG10716" /db_xref="UniProtKB/Swiss-Prot:P25994" /translation="MPKRVDINKILVIGSGPIIIGQAAEFDYAGTQACLALKEEGYEV ILVNSNPATIMTDTEMADRVYIEPLTPEFLTRIIRKERPDAILPTLGGQTGLNLAVEL SERGVLAECGVEVLGTKLSAIQQAEDRDLFRTLMNELNEPVPESEIIHSLEEAEKFVS QIGFPVIVRPAYTLGGTGGGICSNETELKEIVENGLKLSPVHQCLLEKSIAGYKEIEY EVMRDSQDHAIVVCNMENIDPVGIHTGDSIVVAPSQTLSDREYQLLRNVSLKLIRALG IEGGCNVQLALDPDSFQYYIIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLSLDEM MNPVTGKTYAAFEPALDYVVSKIPRWPFDKFESANRKLGTQMKATGEVMAIGRTLEES LLKAVRSLEADVYHLELKDAADISDELLEKRIKKAGDERLFYLAEAYRRGYTVEDLHE FSAIDVFFLHKLFGIVQFEKELKANAGDTDVLRRAKELGFSDQYISREWKMKESELYS LRKQAGIAPVFKMVDTCAAEFESETPYFYSTYEEENESVVTDKKSVMVLGSGPIRIGQ GVEFDYATVHSVWAIKQAGYEAIIVNNNPETVSTDFSISDKLYFEPLTIEDVMHIIDL EQPMGVVVQFGGQTAINLADELSARGVKILGTSLEDLDRAEDRDKFEQALGELGVPQP LGKTATSVNQAVSIASDIGYPVLVRPSYVLGGRAMEIVYHEEELLHYMKNAVKINPQH PVLIDRYLTGKEIEVDAVSDGETVVIPGIMEHIERAGVHSGDSIAVYPPQSLTEDIKK KIEQYTIALAKGLNIVGLLNIQFVLSQGEVYVLEVNPRSSRTVPFLSKITGIPMANLA TKIILGQKLAAFGYTEGLQPEQQGVFVKAPVFSFAKLRRVDITLGPEMKSTGEVMGKD STLEKALYKALIASGIQIPNYGSVLLTVADKDKEEGLAIAKRFHAIGYNILATEGTAG YLKEASIPAKVVGKIGQDGPNLLDVIRNGEAQFVINTLTKGKQPARDGFRIRRESVEN GVACLTSLDTAEAILRVLESMTFRADQMPAVNTNQEAAVTI*" gene 1623736..1626951 /gene="pyrAB" /locus_tag="BSU_15520" /old_locus_tag="BSU15520" CDS 1626948..1627718 /gene="pyrK" /locus_tag="BSU_15530" /old_locus_tag="BSU15530" /EC_number="1.3.98.1" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:169225, 10545205, 11188687, 15299876" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 169225, 10545205, 11188687, 15299876; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="dihydroorotate dehydrogenase (electron transfer subunit)" /protein_id="NP_389436.1" /db_xref="EnsemblGenomes-Gn:BSU15530" /db_xref="EnsemblGenomes-Tr:CAB13427" /db_xref="GOA:P25983" /db_xref="InterPro:IPR001433" /db_xref="InterPro:IPR012165" /db_xref="InterPro:IPR017927" /db_xref="InterPro:IPR017938" /db_xref="InterPro:IPR019480" /db_xref="InterPro:IPR023455" /db_xref="InterPro:IPR037117" /db_xref="SubtiList:BG10717" /db_xref="UniProtKB/Swiss-Prot:P25983" /translation="MKKAYLTVCSNQQIADRVFQMVLKGELVQGFTTPGQFLHLKVSE AVTPLLRRPISIADVNFEKNEVTIIYRVDGEGTRLLSLKQQGELVDVLGPLGNGFPVN EVQPGKTALLVGGGVGVPPLQELSKRLIEKGVNVIHVLGFQSAKDVFYEEECRQYGDT YVATADGSYGETGFVTDVIKRKKLEFDILLSCGPTPMLKALKQEYAHKEVYLSMEERM GCGIGACFACVCHTNESETSYVKVCLDGPVFKAQEVAL*" gene 1626948..1627718 /gene="pyrK" /locus_tag="BSU_15530" /old_locus_tag="BSU15530" CDS 1627718..1628653 /gene="pyrD" /locus_tag="BSU_15540" /old_locus_tag="BSU15540" /EC_number="1.3.1.15" /experiment="publication(s) with functional evidences, PMID:4380263, 10545205" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 4380263, 10545205; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="dihydroorotate dehydrogenase (catalytic subunit)" /protein_id="NP_389437.1" /db_xref="EnsemblGenomes-Gn:BSU15540" /db_xref="EnsemblGenomes-Tr:CAB13428" /db_xref="GOA:P25996" /db_xref="InterPro:IPR001295" /db_xref="InterPro:IPR005720" /db_xref="InterPro:IPR012135" /db_xref="InterPro:IPR013785" /db_xref="InterPro:IPR024920" /db_xref="InterPro:IPR033888" /db_xref="SubtiList:BG10718" /db_xref="UniProtKB/Swiss-Prot:P25996" /translation="MLEVKLPGLDLKNPIIPASGCFGFGKEFSRFYDLSCLGAIMIKA TTKEPRFGNPTPRVAETGAGMLNAIGLQNPGLDSVLHHELPWLEQFDTPIIANVAGSQ VDDYVEVAEHISKAPNVHALELNISCPNVKTGGIAFGTNPEMAADLTKAVKEVSDVPV YVKLSPNVANITEIALAIEEAGADGLTMINTLIGMRLDLKTGKPILANKTGGLSGPAV KPVAIRMVYEVSQMVNIPIIGMGGVQTAEDALEFLLAGASAVAVGTANFVNPFACPEI IEQLPSVLLQYGYQSIEECIGRSWNHEKQPAHHRA*" gene 1627718..1628653 /gene="pyrD" /locus_tag="BSU_15540" /old_locus_tag="BSU15540" CDS 1628622..1629341 /gene="pyrF" /locus_tag="BSU_15550" /old_locus_tag="BSU15550" /EC_number="4.1.1.23" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:10681442, 11390694, 22720735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10681442, 11390694, 22720735; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="orotidine 5'-phosphate decarboxylase" /protein_id="NP_389438.1" /db_xref="EnsemblGenomes-Gn:BSU15550" /db_xref="EnsemblGenomes-Tr:CAB13429" /db_xref="GOA:P25971" /db_xref="InterPro:IPR001754" /db_xref="InterPro:IPR011060" /db_xref="InterPro:IPR013785" /db_xref="InterPro:IPR014732" /db_xref="InterPro:IPR018089" /db_xref="PDB:1DBT" /db_xref="SubtiList:BG10719" /db_xref="UniProtKB/Swiss-Prot:P25971" /translation="MKNNLPIIALDFASAEETLAFLAPFQQEPLFVKVGMELFYQEGP SIVKQLKERNCELFLDLKLHDIPTTVNKAMKRLASLGVDLVNVHAAGGKKMMQAALEG LEEGTPAGKKRPSLIAVTQLTSTSEQIMKDELLIEKSLIDTVVHYSKQAEESGLDGVV CSVHEAKAIYQAVSPSFLTVTPGIRMSEDAANDQVRVATPAIAREKGSSAIVVGRSIT KAEDPVKAYKAVRLEWEGIKS*" gene 1628622..1629341 /gene="pyrF" /locus_tag="BSU_15550" /old_locus_tag="BSU15550" CDS 1629320..1629970 /gene="pyrE" /locus_tag="BSU_15560" /old_locus_tag="BSU15560" /EC_number="2.4.2.10" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 9305779, 22447609, 23405251; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="orotate phosphoribosyltransferase" /protein_id="NP_389439.1" /db_xref="EnsemblGenomes-Gn:BSU15560" /db_xref="EnsemblGenomes-Tr:CAB13430" /db_xref="GOA:P25972" /db_xref="InterPro:IPR000836" /db_xref="InterPro:IPR004467" /db_xref="InterPro:IPR023031" /db_xref="InterPro:IPR029057" /db_xref="SubtiList:BG10720" /db_xref="UniProtKB/Swiss-Prot:P25972" /translation="MGGNQILKQIIAKHLLDIQAVFLRPNEPFTWASGILSPIYCDNR LTLSFPEVRNDVASGISKLVKEHFPEAEMIAGTATAGIPHAALAADHLNLPMCYVRSK PKAHGKGNQIEGAVQEGQKTVVIEDLISTGGSVLEACAALQAAGCEVLGVVSIFTYGL PKAEEAFAKAELPYYSLTDYDTLTEVALENGNIHSDDLKKLQTWKRNPESKDWFKK*" gene 1629320..1629970 /gene="pyrE" /locus_tag="BSU_15560" /old_locus_tag="BSU15560" downshifts 1629972 /Source="Nicolas_upshifts" /id="D874" /incds=0 /nref=17 /ntot=184 /MaxReadThrough="3.91018" /MaxDrop="5.49939" /score="33.4515727" /energy="-9" /TU="U1287,U1288" /idTUdmin="U1287" /TUdmin="-115" /isTUend="FALSE" S_feature 1630017..1630089 /Source="Nicolas_S_feature" /locus_tag="new_1630017_1630089" /HighExp="Cold, Gly, MG 5, S0, LPh, M/G, GM 60, MG t5, Mal, HPh" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="1, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S568" promotor_-35 1630069..1630076 /Source="Nicolas_upshift_promotors" /id="U1289" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.936063936063936" /psig=1 /xcortree=2889 /SigmaFactorBS="tgaggcctgtttttttattaatcctataaaaaaagtcgGGTT GACTtatgttagaattgTGCTAAAATTTACTACAAATctaaaaacttatcaagagcgg c" /listShort="NA, S569, cysH, cysP, sat, cysC, S570, sumT, sirB, sirC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1630090..1630109 /Source="Nicolas_upshift_promotors" /id="U1289" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.936063936063936" /psig=1 /xcortree=2889 /SigmaFactorBS="tgaggcctgtttttttattaatcctataaaaaaagtcgGGTT GACTtatgttagaattgTGCTAAAATTTACTACAAATctaaaaacttatcaagagcgg c" /listShort="NA, S569, cysH, cysP, sat, cysC, S570, sumT, sirB, sirC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1630091 /Source="Nicolas_upshifts" /id="U1289" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.936063936063936" /psig=1 /xcortree=2889 /SigmaFactorBS="tgaggcctgtttttttattaatcctataaaaaaagtcgGGTT GACTtatgttagaattgTGCTAAAATTTACTACAAATctaaaaacttatcaagagcgg c" /listShort="NA, S569, cysH, cysP, sat, cysC, S570, sumT, sirB, sirC" /GFF_Attribute="listLong" misc_RNA 1630115..1630220 /gene="mswE" /locus_tag="BSU_misc_RNA_29" /product="S-adenosylmethionine riboswitch" /experiment="publication(s) with functional evidences, PMID:10094622, 12626738, 12910260, 17381305, 18039762" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10094622, 12626738, 12910260, 17381305, 18039762; Product type n: RNA" gene 1630115..1630220 /gene="mswE" /locus_tag="BSU_misc_RNA_29" S_feature 1630221..1630381 /Source="Nicolas_S_feature" /locus_tag="new_1630221_1630381" /HighExp="MG 10, B60, MG 5, MG t5, M9-exp, MG 25, MG 60, MG 15, GM 90, GM 25" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="SigA, SigA" /TUlongPSig="1, 1" /label="S569" CDS 1630382..1631083 /gene="cysH" /locus_tag="BSU_15570" /old_locus_tag="BSU15570" /EC_number="1.8.4.8" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:10094622, 11004190, 12072441, 16267287, 18456801" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10094622, 11004190, 12072441, 16267287, 18456801; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="(phospho)adenosine phosphosulfate reductase" /protein_id="NP_389440.1" /db_xref="EnsemblGenomes-Gn:BSU15570" /db_xref="EnsemblGenomes-Tr:CAB13431" /db_xref="GOA:P94498" /db_xref="InterPro:IPR002500" /db_xref="InterPro:IPR004511" /db_xref="InterPro:IPR011798" /db_xref="InterPro:IPR014729" /db_xref="SubtiList:BG11930" /db_xref="UniProtKB/Swiss-Prot:P94498" /translation="MLTYDNWEEPTITFPEDDPYKGALSVLKWAYGHYGDQLVYACSF GIEGIVLIDLIYKVKKDAEIVFLDTGLHFKETYETIERVKERYPGLNIILKKPDLTLE EQAEEHGDKLWEREPNQCCYLRKVVPLREALSGHPAWLSGLRRDQGPSRANTNFLNKD EKFKSVKVCPLIHWTWKDIWRYTSRNELDYNPLHDQGYPSIGCAPCTSPAFTAEDLRS GRWNGMAKTECGLHE*" gene 1630382..1631083 /gene="cysH" /locus_tag="BSU_15570" /old_locus_tag="BSU15570" CDS 1631095..1632159 /gene="cysP" /locus_tag="BSU_15580" /old_locus_tag="BSU15580" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:10094622, 10784039, 11004190, 15849754, 16850406, 22720735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10094622, 10784039, 11004190, 15849754, 16850406, 22720735; Product type t : transporter" /codon_start=1 /transl_table=11 /product="sulfate permease" /protein_id="NP_389441.1" /db_xref="EnsemblGenomes-Gn:BSU15580" /db_xref="EnsemblGenomes-Tr:CAB13432" /db_xref="GOA:O34734" /db_xref="InterPro:IPR001204" /db_xref="SubtiList:BG13377" /db_xref="UniProtKB/Swiss-Prot:O34734" /translation="MELAAILFSLFFAMNIGASGAAASMGVAYGSGAIKKKTYALILC AVGVFAGAVIGGGEVVKTISSGIIPEQTITLTIVCIIIGAAALSLFTANLLGIPLSTS EVTVGAVVGVGVAYKVLFVNNLLIIVSFWVFVPLFAFGFTYFVSKLFRYFKIEVKSSK KQKILGIVLLVAGFFEAFSAGMNNVANAVGPLVAAGVLDVGKGTLYGGAFVALGALLL GRRVLETNGKKITRFSKGEGILLSGTGAGLVIISSVFGMPVPLAQVTSSSIIGIGMAK NGPNVFHKQVVQTMLKVWIVSPFLSLSISYLLVSLFLKADYYSIFIMVSVLLAAGGAI SLTKAIRKERRSVHEQGGGI*" gene 1631095..1632159 /gene="cysP" /locus_tag="BSU_15580" /old_locus_tag="BSU15580" CDS 1632208..1633356 /gene="sat" /locus_tag="BSU_15590" /old_locus_tag="BSU15590" /EC_number="2.7.7.4" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 10094622, 11004190, 11274114; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="sulfate adenylyltransferase" /protein_id="NP_389442.1" /db_xref="EnsemblGenomes-Gn:BSU15590" /db_xref="EnsemblGenomes-Tr:CAB13433" /db_xref="GOA:O34764" /db_xref="InterPro:IPR002650" /db_xref="InterPro:IPR014729" /db_xref="InterPro:IPR015947" /db_xref="InterPro:IPR020792" /db_xref="InterPro:IPR024951" /db_xref="InterPro:IPR025980" /db_xref="SubtiList:BG13378" /db_xref="UniProtKB/Swiss-Prot:O34764" /translation="MSLAPHGGTLVNRVDESYDVSGIQKEIELDLISFADLELIGIGA YSPIEGFFNEKDYVSVVENMRLSSGVVWSLPITLPVDAQKAAELSLGETVKLTYEGET YGVIQIEDLYVPDKQKEAVNVYKTDEQEHPGVKKLFSRGNTYVGGPITLIKKASKQFP EFTFEPSETRRQFAEKGWETIVGFQTRNPVHRAHEYIQKTALETVDGLFLNPLVGETK SDDIPADVRMESYQVLLDHYYPKDRVFLGVFLAAMRYAGPREAIFHALVRKNYGCTHF IVGRDHAGVGDYYGTYEAQELFDTFKPEELGITPLKFEHSFFCKKCGNMGTAKTCPHG REHHVILSGTKVRGMLRDGVLPPAEFSRKEVVEVLIKGMKKKEEVGVS*" gene 1632208..1633356 /gene="sat" /locus_tag="BSU_15590" /old_locus_tag="BSU15590" upshifts complement(1632297) /Source="Nicolas_upshifts" /id="U1290" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.978021978021978" /psig="0.007992007992008" /xcortree=27 /SigmaFactorBS="accttcaatcgggctgtatgcaccgATaccgatcaattccaa atCCGCGaaagaaattaaatcaagttcaatttctttttgaatgccgctcacatcatat g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 complement(1632309..1632313) /Source="Nicolas_upshift_promotors" /id="U1290" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.978021978021978" /psig="0.007992007992008" /xcortree=27 /SigmaFactorBS="accttcaatcgggctgtatgcaccgATaccgatcaattccaa atCCGCGaaagaaattaaatcaagttcaatttctttttgaatgccgctcacatcatat g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 complement(1632331..1632332) /Source="Nicolas_upshift_promotors" /id="U1290" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.978021978021978" /psig="0.007992007992008" /xcortree=27 /SigmaFactorBS="accttcaatcgggctgtatgcaccgATaccgatcaattccaa atCCGCGaaagaaattaaatcaagttcaatttctttttgaatgccgctcacatcatat g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" CDS 1633369..1633962 /gene="cysC" /locus_tag="BSU_15600" /old_locus_tag="BSU15600" /EC_number="2.7.1.25" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 1332767, 10094622, 11004190, 19067028, 22720735; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="adenylylsulfate kinase" /protein_id="NP_389443.1" /db_xref="EnsemblGenomes-Gn:BSU15600" /db_xref="EnsemblGenomes-Tr:CAB13434" /db_xref="GOA:O34577" /db_xref="InterPro:IPR002891" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG13379" /db_xref="UniProtKB/Swiss-Prot:O34577" /translation="MTNRDIVWHEASITKEEYQQKNKHKSSILWLTGLSGSGKSTIAN AAARELFEQGYQVIVLDGDNIRHGLNRDLGFSDEDRKENIRRIGEVAKLFVQQGTIVI TAFISPFREDRQQVRELVEAGEFNEVYIKCDLDICEQRDPKGLYKKARNGEIPFFTGI DSPYEEPEAPELVLDSGQHDREACKNQLIEFVKQKLS*" gene 1633369..1633962 /gene="cysC" /locus_tag="BSU_15600" /old_locus_tag="BSU15600" S_feature 1633963..1634060 /Source="Nicolas_S_feature" /locus_tag="new_1633963_1634060" /HighExp="MG 10, B36, MG 5, MG t5, B60, MG 15, MG 90, MG-0.2, MG 60, MG 45" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="SigA, SigA" /TUlongPSig="1, 1" /label="S570" CDS 1634061..1634834 /gene="sumT" /locus_tag="BSU_15610" /old_locus_tag="BSU15610" /EC_number="2.1.1.107" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1c: Function from experimental evidences in the studied genus; PubMedId: 1906874, 11004190, 10094622, 19154787; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="uroporphyrinogen III and precorrin-1 C-methyltransferase" /protein_id="NP_389444.1" /db_xref="EnsemblGenomes-Gn:BSU15610" /db_xref="EnsemblGenomes-Tr:CAB13435" /db_xref="GOA:O34744" /db_xref="InterPro:IPR000878" /db_xref="InterPro:IPR003043" /db_xref="InterPro:IPR006366" /db_xref="InterPro:IPR014776" /db_xref="InterPro:IPR014777" /db_xref="InterPro:IPR035996" /db_xref="SubtiList:BG13380" /db_xref="UniProtKB/Swiss-Prot:O34744" /translation="MGKVYIVGAGPGDPDLLTIKALKAIEKADVILYDRLVNKEILQY AKEQADLIYCGKLPDFHTMKQETINRFLVKYAQKGKMVVRLKGGDPFVFGRGGEEAEC LSENGIPFEIIPGITSGIAAAAYAGIPVTHRDAGSNVAFVTGHYKKEEDFEEKWKALA TGIDTLVIYMGIKNVQQIERKLLENGRDGSTPAAFIHWGTTDKQKSVFCTVDTLSETV IKENITNPSLIVIGNVVNYHYKLEWFESELKKQDLSEAL*" gene 1634061..1634834 /gene="sumT" /locus_tag="BSU_15610" /old_locus_tag="BSU15610" promotor_-35 1634739..1634746 /Source="Nicolas_upshift_promotors" /id="U1291" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.763236763236763" /psig=1 /xcortree=1738 /SigmaFactorBS="ttcagaaacggtgataaaagaaaacattacaaatccgAGTTT AATtgtcattggaaatgTTGTAAATTATCACTATAAGctggaatggtttgaatctgaa c" /listShort="sirB, sirC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1634761..1634780 /Source="Nicolas_upshift_promotors" /id="U1291" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.763236763236763" /psig=1 /xcortree=1738 /SigmaFactorBS="ttcagaaacggtgataaaagaaaacattacaaatccgAGTTT AATtgtcattggaaatgTTGTAAATTATCACTATAAGctggaatggtttgaatctgaa c" /listShort="sirB, sirC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1634762 /Source="Nicolas_upshifts" /id="U1291" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.763236763236763" /psig=1 /xcortree=1738 /SigmaFactorBS="ttcagaaacggtgataaaagaaaacattacaaatccgAGTTT AATtgtcattggaaatgTTGTAAATTATCACTATAAGctggaatggtttgaatctgaa c" /listShort="sirB, sirC" /GFF_Attribute="listLong" CDS 1634837..1635622 /gene="sirB" /locus_tag="BSU_15620" /old_locus_tag="BSU15620" /EC_number="4.99.1.4" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1c: Function from experimental evidences in the studied genus; PubMedId: 10094622, 11004190, 12408752; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="sirohydrochlorin ferrochelatase" /protein_id="NP_389445.1" /db_xref="EnsemblGenomes-Gn:BSU15620" /db_xref="EnsemblGenomes-Tr:CAB13436" /db_xref="GOA:O34632" /db_xref="InterPro:IPR002762" /db_xref="SubtiList:BG13381" /db_xref="UniProtKB/Swiss-Prot:O34632" /translation="MKQAILYVGHGSRVKKAQQEAAAFLEGCKAHISVPVQEISFLEL QEPTIETGFEACVKQGATHIAVVPLLLLTAAHAKHDIPEEIVRVASRYPSVRISYGKP IGIDEEVVKAVYHRMKDIGVPYENARVVLIGRGSSDPDVKRDVTGIANLLQEMVPVKE VIPCFLTACGPNYKEVFSELEKDDGITTFIVPYLLFTGMLMNEIEREVQKLKAHNPNV YLSSYIGFHPHVKNAFLNRVRETAANSEGQFDFDGGSYASAAH*" gene 1634837..1635622 /gene="sirB" /locus_tag="BSU_15620" /old_locus_tag="BSU15620" CDS 1635603..1636091 /gene="sirC" /locus_tag="BSU_15630" /old_locus_tag="BSU15630" /EC_number="1.3.1.76" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1c: Function from experimental evidences in the studied genus; PubMedId: 10094622, 11004190, 12408752, 18588505; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="precorrin-2 dehydrogenase" /protein_id="NP_389446.1" /db_xref="EnsemblGenomes-Gn:BSU15630" /db_xref="EnsemblGenomes-Tr:CAB13437" /db_xref="GOA:O34813" /db_xref="InterPro:IPR006367" /db_xref="InterPro:IPR028161" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG13382" /db_xref="UniProtKB/Swiss-Prot:O34813" /translation="MLPLHISLEKKKVVIAGGGSIALRRLKTVISEGADITLVSPDVE PEIKQMAEERRIKWEKRTIEKEDYLNAFFIIAATDNAAVNKEIAQSASPFQLVNCVSD AELGNVYMPKIVKRGHVTVSVSTSGASPKHTKELAENVDKLIDGDFVAEVNRLYQMRR KK*" gene 1635603..1636091 /gene="sirC" /locus_tag="BSU_15630" /old_locus_tag="BSU15630" downshifts 1636071 /Source="Nicolas_upshifts" /id="D875" /incds=0 /nref=256 /ntot=267 /MaxReadThrough="2.85828" /MaxDrop="8.90139" /score="26.5923498" /energy="-16.6" /TU="U1289" /idTUdmin="U1291" /TUdmin=0 /isTUend="TRUE" downshifts complement(1636118) /Source="Nicolas_upshifts" /id="D876" /incds=0 /nref=149 /ntot=238 /MaxReadThrough="1.71588" /MaxDrop="5.36964" /score="15.559144" /energy="-16.6" /TU="NA" /idTUdmin="U1292" /TUdmin=7 /isTUend="TRUE" CDS complement(1636131..1637849) /gene="fbnA" /locus_tag="BSU_15640" /old_locus_tag="BSU15640" /function="16.9: Replicate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1b: Function from experimental evidences in the studied species; PubMedId: 11238985, 17586671, 24646681, 28294433; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative tRNA modification protein" /protein_id="NP_389447.1" /db_xref="EnsemblGenomes-Gn:BSU15640" /db_xref="EnsemblGenomes-Tr:CAB13438" /db_xref="InterPro:IPR008532" /db_xref="SubtiList:BG13383" /db_xref="UniProtKB/Swiss-Prot:O34693" /translation="MHMSFDGMFTYGMTHELNEKIMGGRITKIHQPYKHDVIFHIRAK GKNQKLLLSAHPSYSRVHITAQAYENPSEPPMFCMLLRKHIEGGFIEKIEQAGLDRIM IFHIKSRNEIGDETVRKLYVEIMGRHSNIILTDAAENVIIDGLKHLSPSMNSYRTVLP GQDYKLPPAQDKISPLEASEDDILRHLSFQEGRLDKQIVDHFSGVSPLFAKEAVHRAG LANKVTLPKALLALFAEVKEHRFIPNITTVNGKEYFYLLELTHLKGEARRFDSLSELL DRFYFGKAERDRVKQQAQDLERFVVNERKKNANKIKKLEKTLEYSENAKEFQLYGELL TANLYMLKKGDKQAEVINYYDEESPTITIPLNPNKTPSENAQAYFTKYQKAKNSVAVV EEQIRLAQEEIEYFDQLIQQLSSASPRDISEIREELVEGKYLRPKQQKGQKKQKPHNP VLETYESTSGLTILVGKNNRQNEYLTTRVAARDDIWLHTKDIPGSHVVIRSSEPDEQT IMEAATIAAYFSKAKDSSSVPVDYTKIRHVKKPNGAKPGFVTYDSQHTVFVTPDADTV IKLKKS*" gene complement(1636131..1637849) /gene="fbnA" /locus_tag="BSU_15640" /old_locus_tag="BSU15640" promotor_-10 complement(1637871..1637890) /Source="Nicolas_upshift_promotors" /id="U1292" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.766233766233766" /psig="0.999000999001" /xcortree=2006 /SigmaFactorBS="gctctcttatagagatatcactctataagcatgcttaTTCTG ActcgtcccatttCATGCTATAATTATCGAATGcaggaagaatgagagggtgtattgc a" /listShort="yloA" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 1637885..1637890 /Source="Nicolas_upshift_promotors" /id="U1293" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.996003996003996" /psig="0.996003996003996" /xcortree=989 /SigmaFactorBS="tacaccctctcattcttcctgcattcgataattatAGCATGa aatgggacgagtcaGAATAAGCATGCTTATAGAgtgatatctctataagagagcaggg g" /listShort="yloB, S571, yloC, ylzA, gmk, rpoZ" /listLong="coaBC" /label="promotor_-35" upshifts complement(1637885) /Source="Nicolas_upshifts" /id="U1292" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.766233766233766" /psig="0.999000999001" /xcortree=2006 /SigmaFactorBS="gctctcttatagagatatcactctataagcatgcttaTTCTG ActcgtcccatttCATGCTATAATTATCGAATGcaggaagaatgagagggtgtattgc a" /listShort="yloA" /GFF_Attribute="listLong" promotor_-35 complement(1637903..1637908) /Source="Nicolas_upshift_promotors" /id="U1292" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.766233766233766" /psig="0.999000999001" /xcortree=2006 /SigmaFactorBS="gctctcttatagagatatcactctataagcatgcttaTTCTG ActcgtcccatttCATGCTATAATTATCGAATGcaggaagaatgagagggtgtattgc a" /listShort="yloA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1637906..1637924 /Source="Nicolas_upshift_promotors" /id="U1293" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.996003996003996" /psig="0.996003996003996" /xcortree=989 /SigmaFactorBS="tacaccctctcattcttcctgcattcgataattatAGCATGa aatgggacgagtcaGAATAAGCATGCTTATAGAgtgatatctctataagagagcaggg g" /listShort="yloB, S571, yloC, ylzA, gmk, rpoZ" /listLong="coaBC" /label="promotor_-10" upshifts 1637910 /Source="Nicolas_upshifts" /id="U1293" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.996003996003996" /psig="0.996003996003996" /xcortree=989 /SigmaFactorBS="tacaccctctcattcttcctgcattcgataattatAGCATGa aatgggacgagtcaGAATAAGCATGCTTATAGAgtgatatctctataagagagcaggg g" /listShort="yloB, S571, yloC, ylzA, gmk, rpoZ" /listLong="coaBC" CDS 1637965..1640637 /gene="tcaB" /locus_tag="BSU_15650" /old_locus_tag="BSU15650" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:12161109, 24415722" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12161109, 24415722; Product type t: transporter" /codon_start=1 /transl_table=11 /product="P-type calcium transport ATPase (sporulation)" /protein_id="NP_389448.1" /db_xref="EnsemblGenomes-Gn:BSU15650" /db_xref="EnsemblGenomes-Tr:CAB13439" /db_xref="GOA:O34431" /db_xref="InterPro:IPR001757" /db_xref="InterPro:IPR004014" /db_xref="InterPro:IPR005782" /db_xref="InterPro:IPR006068" /db_xref="InterPro:IPR008250" /db_xref="InterPro:IPR018303" /db_xref="InterPro:IPR023214" /db_xref="InterPro:IPR023298" /db_xref="InterPro:IPR023299" /db_xref="InterPro:IPR036412" /db_xref="SubtiList:BG13384" /db_xref="UniProtKB/Swiss-Prot:O34431" /translation="MKFHEMGQTDLLEATNTSMKQGLTEKEVKKRLDKHGPNELQEGK KTSALLLFFAQFKDFMVLVLLAATLISGFLGEYVDAVAIIAIVFVNGILGFFQERRAE QSLQALKELSTPHVMALREGSWTKIPSKELVPGDIVKFTSGDRIGADVRIVEARSLEI EESALTGESIPVVKHADKLKKPDVSLGDITNMAFMGTIVTRGSGVGVVVGTGMNTAMG KIADMLESAGTLSTPLQRRLEQLGKILIVVALLLTVLVVAVGVIQGHDLYSMFLAGVS LAVAAIPEGLPAIVTVALSLGVQRMIKQKSIVRKLPAVETLGCASIICSDKTGTMTQN KMTVTHVWSGGKTWRVAGAGYEPKGSFTLNEKEISVNEHKPLQQMLLFGALCNNSNIE KRDGEYVLDGDPTEGALLTAARKGGFSKEFVESNYRVIEEFPFDSARKMMTVIVENQD RKRYIITKGAPDVLMQRSSRIYYDGSAALFSNERKAETEAVLRHLASQALRTIAVAYR PIKAGETPSMEQAEKDLTMLGLSGIIDPPRPEVRQAIKECREAGIKTVMITGDHVETA KAIAKDLRLLPKSGKIMDGKMLNELSQEELSHVVEDVYVFARVSPEHKLKIVKAYQEN GHIVAMTGDGVNDAPAIKQADIGVSMGITGTDVAKEASSLVLVDDNFATIKSAIKEGR NIYENIRKFIRYLLASNVGEILVMLFAMLLALPLPLVPIQILWVNLVTDGLPAMALGM DQPEGDVMKRKPRHPKEGVFARKLGWKVVSRGFLIGVATILAFIIVYHRNPENLAYAQ TIAFATLVLAQLIHVFDCRSETSVFSRNPFQNLYLIGAVLSSILLMLVVIYYPPLQPI FHTVAITPGDWMLVIGMSAIPTFLLAGSLLTRKK*" gene 1637965..1640637 /gene="tcaB" /locus_tag="BSU_15650" /old_locus_tag="BSU15650" promotor_-10 complement(1639370..1639389) /Source="Nicolas_upshift_promotors" /id="U1294" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.914085914085914" /psig="0.98001998001998" /xcortree=1702 /SigmaFactorBS="ttaataccgcctctgtttctgcttttctttCATTTGAAaaaa gagccgctgaGCCATCATAATAAATACGGGaagatcgctgcatgagtacatccggcgc a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1639381) /Source="Nicolas_upshifts" /id="U1294" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.914085914085914" /psig="0.98001998001998" /xcortree=1702 /SigmaFactorBS="ttaataccgcctctgtttctgcttttctttCATTTGAAaaaa gagccgctgaGCCATCATAATAAATACGGGaagatcgctgcatgagtacatccggcgc a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(1639404..1639411) /Source="Nicolas_upshift_promotors" /id="U1294" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.914085914085914" /psig="0.98001998001998" /xcortree=1702 /SigmaFactorBS="ttaataccgcctctgtttctgcttttctttCATTTGAAaaaa gagccgctgaGCCATCATAATAAATACGGGaagatcgctgcatgagtacatccggcgc a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" misc_feature 1640643..1640662 /Source="Nicolas_upshift_promotors" /id="U1295" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.925074925074925" /psig="0.994005994005994" /xcortree=2170 /SigmaFactorBS="cgccatccctacttttttgctggcggggtcacttttaacaag aaaaaaataaattcaTATGATATAATCTTAGGGGTaatagcgtgtctattgccctttt a" /listShort="S571, yloC, ylzA, gmk, rpoZ, coaBC, priA, defA, fmt, rsmB, yloN, prpC, prkC, cpgA, rpe, thiN, S573, spoVM" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" S_feature 1640646..1640719 /Source="Nicolas_S_feature" /locus_tag="new_1640646_1640719" /HighExp="LPhT, LBGstat, T3.0H, H2O2, T3.30H, Salt, B60, Lbexp, UNK1, C90" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigEF" /TUshortPSig="0.994, 0.996" /TUlongSig="NA" /TUlongPSig="NA" /label="S571" upshifts 1640646 /Source="Nicolas_upshifts" /id="U1295" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.925074925074925" /psig="0.994005994005994" /xcortree=2170 /SigmaFactorBS="cgccatccctacttttttgctggcggggtcacttttaacaag aaaaaaataaattcaTATGATATAATCTTAGGGGTaatagcgtgtctattgccctttt a" /listShort="S571, yloC, ylzA, gmk, rpoZ, coaBC, priA, defA, fmt, rsmB, yloN, prpC, prkC, cpgA, rpe, thiN, S573, spoVM" /GFF_Attribute="listLong" CDS 1640720..1641595 /gene="yloC" /locus_tag="BSU_15660" /old_locus_tag="BSU15660" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_389449.1" /db_xref="EnsemblGenomes-Gn:BSU15660" /db_xref="EnsemblGenomes-Tr:CAB13440" /db_xref="InterPro:IPR005229" /db_xref="InterPro:IPR013527" /db_xref="InterPro:IPR013551" /db_xref="SubtiList:BG13385" /db_xref="UniProtKB/Swiss-Prot:O34441" /translation="MIRSMTGFGSASKTQDDLSVSVELKSVNYRFKEVNARLPRPLLY FEDKLKQTILQHIQRGRIELFVSVDSDMLVEKRLEIDWPLLDEFVAAARDMKKRYQLS AEPDVMDFFKLDHVVQVHEEQTQNDKLEALIIDAAEEAVKGLCEMREKEGLLLAKDCL MHIDQLEELVRETELLAADVVSRYRERLYARIKEWTEDVLDESRLVTECAIFADRSDI TEEITRLKSHFAQFRDILASGGAVGRKLDFLVQELNREANTIGSKANDHQITKLVVEM KSSIEKIKEQVQNIE*" gene 1640720..1641595 /gene="yloC" /locus_tag="BSU_15660" /old_locus_tag="BSU15660" CDS 1641672..1641941 /gene="remA" /locus_tag="BSU_15670" /old_locus_tag="BSU15670" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:19363116, 23396918, 23646920" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 19363116, 23396918, 23646920; Product type r: regulator" /codon_start=1 /transl_table=11 /product="essential sporulation DNA binding protein; regulator of biofilm formation" /protein_id="NP_570902.1" /db_xref="EnsemblGenomes-Gn:BSU15670" /db_xref="EnsemblGenomes-Tr:CAE01452" /db_xref="InterPro:IPR007169" /db_xref="SubtiList:BG14185" /db_xref="UniProtKB/Swiss-Prot:Q7WY72" /translation="MTIKLINIGFGNIISANRMISIVSPESAPIKRMIQDARDRGMLI DATYGRRTRAVVVMDSDHIILSAVQPETVAHRLSVKEEIMDEGQG*" gene 1641672..1641941 /gene="remA" /locus_tag="BSU_15670" /old_locus_tag="BSU15670" misc_feature complement(1641752..1641756) /Source="Nicolas_upshift_promotors" /id="U1296" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.889110889110889" /psig="0.001998001998002" /xcortree=58 /SigmaFactorBS="ccgtatgtagcgtcaattagcattccgcggtctcttgcatcc tgaatcatccgtttgattgGCGCAgactccgggctgacaatcgaaatcatccgattgg c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(1641757) /Source="Nicolas_upshifts" /id="U1296" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.889110889110889" /psig="0.001998001998002" /xcortree=58 /SigmaFactorBS="ccgtatgtagcgtcaattagcattccgcggtctcttgcatcc tgaatcatccgtttgattgGCGCAgactccgggctgacaatcgaaatcatccgattgg c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" CDS 1641949..1642563 /gene="gmk" /locus_tag="BSU_15680" /old_locus_tag="BSU15680" /EC_number="2.7.4.8" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:12682299, 17012781, 24722991" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12682299, 17012781, 24722991; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="guanylate kinase" /protein_id="NP_389450.2" /db_xref="EnsemblGenomes-Gn:BSU15680" /db_xref="EnsemblGenomes-Tr:CAB13441" /db_xref="GOA:O34328" /db_xref="InterPro:IPR008144" /db_xref="InterPro:IPR008145" /db_xref="InterPro:IPR017665" /db_xref="InterPro:IPR020590" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG13386" /db_xref="UniProtKB/Swiss-Prot:O34328" /translation="MKERGLLIVLSGPSGVGKGTVRQAIFSQEDTKFEYSISVTTRSP REGEVNGVDYFFKTRDEFEQMIADNKLLEWAEYVGNYYGTPVDYVEQTLQDGKDVFLE IEVQGALQVRNAFPEGLFIFLAPPSLSELKNRIVTRGTETDALIENRMKAAKAEIEMM DAYDYVVENDNVETACDKIKAIVLAEHLKRERVAPRYKKMLEVE*" gene 1641949..1642563 /gene="gmk" /locus_tag="BSU_15680" /old_locus_tag="BSU15680" CDS 1642567..1642770 /gene="rpoZ" /locus_tag="BSU_15690" /old_locus_tag="BSU15690" /function="16.2: Construct biomass (Anabolism)" /function="16.3: Control" /function="16.9: Replicate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 12089032, 16159791, 17233676, 24476911, 25878038; Product type f: factor" /codon_start=1 /transl_table=11 /product="omega subunit of RNA polymerase" /protein_id="NP_389451.1" /db_xref="EnsemblGenomes-Gn:BSU15690" /db_xref="EnsemblGenomes-Tr:CAB13442" /db_xref="GOA:O35011" /db_xref="InterPro:IPR003716" /db_xref="InterPro:IPR006110" /db_xref="InterPro:IPR012293" /db_xref="InterPro:IPR036161" /db_xref="SubtiList:BG13387" /db_xref="UniProtKB/Swiss-Prot:O35011" /translation="MLDPSIDSLMNKLDSKYTLVTVSARRAREMQIKKDQMIEHTISH KYVGKALEEIDAGLLSFEKEDRE*" gene 1642567..1642770 /gene="rpoZ" /locus_tag="BSU_15690" /old_locus_tag="BSU15690" downshifts 1642759 /Source="Nicolas_upshifts" /id="D877" /incds=0 /nref=118 /ntot=257 /MaxReadThrough="5.65143" /MaxDrop="4.7291" /score="-8.13961715" /energy="-7.7" /TU="U1293,U1295" /idTUdmin="U1293" /TUdmin="-132" /isTUend="FALSE" CDS 1642851..1644071 /gene="coaBC" /locus_tag="BSU_15700" /old_locus_tag="BSU15700" /EC_number="4.1.1.36" /EC_number="6.3.2.5" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 11278255, 11358972, 12140293, 14686929, 15530362; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="coenzyme A biosynthesis bifunctional protein CoaBC; phosphopantothenoylcysteine synthetase/decarboxylase" /protein_id="NP_389452.1" /db_xref="EnsemblGenomes-Gn:BSU15700" /db_xref="EnsemblGenomes-Tr:CAB13443" /db_xref="GOA:O35033" /db_xref="InterPro:IPR003382" /db_xref="InterPro:IPR005252" /db_xref="InterPro:IPR007085" /db_xref="InterPro:IPR035929" /db_xref="InterPro:IPR036551" /db_xref="SubtiList:BG13388" /db_xref="UniProtKB/Swiss-Prot:O35033" /translation="MLNNRNVLLCVSGGIAVYKACALTSKLVQAGANVKVIMTESACR FVSPLTFQALSRHEVYTDTFKEQNPSVISHIDAADWADLIIVAPATANVIGKLANGIA DDMLTTTLLAATAPVWIAPAMNVHMYDHPAVKRNISVLYQDGYCFIEPSEGYLACGYV GKGRLEEPENIVKLAEKHFAEETSAPLEGKHVVITAGPTREAIDPVRFFTNKSTGKMG YALAEAAVQLGARVILISGPVSLDQPKGLAEFIPVQSAADMREAVLSVYDASDIVIKT AAVADFTPKTVFDHKMKKQDGGMTLELKRTVDILKELGEKKKEQILVGFAAETQDIEH YARKKLAAKNLDLIVANDVKANGAGFGADTNIVTIFFKDGHKRELPIMSKLDVSFEIL QEIAALSKQTGERS*" gene 1642851..1644071 /gene="coaBC" /locus_tag="BSU_15700" /old_locus_tag="BSU15700" S_feature complement(1643910..1644485) /Source="Nicolas_S_feature" /locus_tag="new_1643910_1644485_c" /HighExp="Etha, Salt, Sw, Gly, C30, M9-stat, B60, LPhT, HiTm, Heat" /AntisenseName="priA" /AntisenseCor="-5.1213364637925501E-2" /AntisenseRegPval="-0.4" /CDS_PredictionProba="NA" /TUshortSig="SigB" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S572" CDS 1644068..1646485 /gene="priA" /locus_tag="BSU_15710" /old_locus_tag="BSU15710" /function="16.9: Replicate" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:10572298, 11917020, 12682299, 21170359, 22720735, 28527403" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10572298, 11917020, 12682299, 21170359, 22720735, 28527403; Product type f : factor" /codon_start=1 /transl_table=11 /product="primosomal replication factor Y (primosomal protein N')" /protein_id="NP_389453.1" /db_xref="EnsemblGenomes-Gn:BSU15710" /db_xref="EnsemblGenomes-Tr:CAB13444" /db_xref="GOA:P94461" /db_xref="InterPro:IPR001650" /db_xref="InterPro:IPR005259" /db_xref="InterPro:IPR006935" /db_xref="InterPro:IPR014001" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR036388" /db_xref="SubtiList:BG11963" /db_xref="UniProtKB/Swiss-Prot:P94461" /translation="MNFAEVIVDVSTKNIDRPFDYKIPDHLKGMIKTGMRVIVPFGPR KIQGFVTAVKEASDLSGKSVKEVEDLLDLTPVLTEELMILSSWLSDKTLSFKITALQA MLPAALKAKYEKELKIAHGADLPPQVERLFSETKTLLYSDIPDHETLKLIQRHVQKGD IDVTYKVAQKTNKKMVRHIQANASKEELAKQAEGLSRQAAKQQAILHFLISEPEGVKI PAAELCKKTDTSSATIKTLIQKGLLKESYEEVYRDPYQDKMFKKTEPLPLTDEQRAAF EPIRETLDSDEHKVFLLHGVTGSGKTEIYLQSIEKVLAKGKEAIVLVPEISLTPQMVN RFKGRFGSQVAVMHSGLSTGEKYDEWRKIHRKEVRLVVGARSAIFAPFENLGMIIIDE EHESSYKQEEMPRYHAKEVAIKRAEHHSCPVVLGSATPTLESYARAQKGVYELLSLKH RVNHRVMPEVSLVDMREELRNGNRSMFSVELMEKLEETIAKGEQAVLFLNKRGYSSFV MCRDCGYVPQCPHCDISMTYHRYGQRLKCHYCGHEEPVPHTCPECASEHIRFFGTGTQ RVEEELTKVLPSARVIRMDVDTTSRKGAHEKLLSAFGEGKADILLGTQMIAKGLDFPN VTLVGVLSADTTLHIPDFRSAEKTFQLLTQVSGRAGRHEKPGHVIIQTYTPSHYSIQL TKTHDYETFYQHEMAHRREQSYPPYYYLALVTVSHEEVAKAAVTAEKIAHFLKANCGA DTKILGPSASPIARIKDRYRYQCVIKYKQETQLSALLKKILEHYKREIEQKHVMISID MNPYMMM*" gene 1644068..1646485 /gene="priA" /locus_tag="BSU_15710" /old_locus_tag="BSU15710" promotor_-10 complement(1644481..1644499) /Source="Nicolas_upshift_promotors" /id="U1297" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=253 /SigmaFactorBS="cccctttttgaacatgcctttgaatcAGTTTCAgcgtctcat gatcGGGTATATCTGAATACAGCagcgtctttgtttcagaaaacagccgttccacttg c" /listShort="S572" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1644485) /Source="Nicolas_upshifts" /id="U1297" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=253 /SigmaFactorBS="cccctttttgaacatgcctttgaatcAGTTTCAgcgtctcat gatcGGGTATATCTGAATACAGCagcgtctttgtttcagaaaacagccgttccacttg c" /listShort="S572" /GFF_Attribute="listLong" promotor_-35 complement(1644513..1644519) /Source="Nicolas_upshift_promotors" /id="U1297" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=253 /SigmaFactorBS="cccctttttgaacatgcctttgaatcAGTTTCAgcgtctcat gatcGGGTATATCTGAATACAGCagcgtctttgtttcagaaaacagccgttccacttg c" /listShort="S572" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1646336..1646340 /Source="Nicolas_upshift_promotors" /id="U1298" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.877122877122877" /psig=1 /xcortree=2458 /SigmaFactorBS="caagcgcgtcgccgatagccaggatcaaaGATAGatatcgct atcaatgCGTGATAAAATACAAACAGGaaacccagttatccgctttattgaagaagat a" /listShort="defA, fmt, rsmB, yloN, prpC, prkC, cpgA, rpe, thiN, S573, spoVM" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1646356..1646375 /Source="Nicolas_upshift_promotors" /id="U1298" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.877122877122877" /psig=1 /xcortree=2458 /SigmaFactorBS="caagcgcgtcgccgatagccaggatcaaaGATAGatatcgct atcaatgCGTGATAAAATACAAACAGGaaacccagttatccgctttattgaagaagat a" /listShort="defA, fmt, rsmB, yloN, prpC, prkC, cpgA, rpe, thiN, S573, spoVM" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1646367 /Source="Nicolas_upshifts" /id="U1298" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.877122877122877" /psig=1 /xcortree=2458 /SigmaFactorBS="caagcgcgtcgccgatagccaggatcaaaGATAGatatcgct atcaatgCGTGATAAAATACAAACAGGaaacccagttatccgctttattgaagaagat a" /listShort="defA, fmt, rsmB, yloN, prpC, prkC, cpgA, rpe, thiN, S573, spoVM" /GFF_Attribute="listLong" CDS 1646512..1646994 /gene="defA" /locus_tag="BSU_15720" /old_locus_tag="BSU15720" /EC_number="3.5.1.88" /function="16.2: Construct biomass (Anabolism)" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:11429456, 16014871, 16207374" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11429456, 16014871, 16207374; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="peptide deformylase" /protein_id="NP_389454.1" /db_xref="EnsemblGenomes-Gn:BSU15720" /db_xref="EnsemblGenomes-Tr:CAB13445" /db_xref="GOA:P94462" /db_xref="InterPro:IPR023635" /db_xref="InterPro:IPR036821" /db_xref="SubtiList:BG11933" /db_xref="UniProtKB/Swiss-Prot:P94462" /translation="MAVKKVVTHPAEVLETPAETVTVFDKKLKKLLDDMYDTMLEMDG VGLAAPQIGILKRAAVVEIGDDRGRIDLVNPEILEKSGEQTGIEGCLSFPNVYGDVTR ADYVKVRAFNRQGKPFILEARGFLARAVQHEMDHLDGVLFTSKISKYYTEDELADMEG *" gene 1646512..1646994 /gene="defA" /locus_tag="BSU_15720" /old_locus_tag="BSU15720" CDS 1646999..1647952 /gene="fmt" /locus_tag="BSU_15730" /old_locus_tag="BSU15730" /EC_number="2.1.2.9" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:769821, 769822, 98518, 9843487, 10858337, 26888283, 27983482" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 769821, 769822, 98518, 9843487, 10858337, 26888283, 27983482; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="methionyl-tRNA formyltransferase" /protein_id="NP_389455.1" /db_xref="EnsemblGenomes-Gn:BSU15730" /db_xref="EnsemblGenomes-Tr:CAB13446" /db_xref="GOA:P94463" /db_xref="InterPro:IPR001555" /db_xref="InterPro:IPR002376" /db_xref="InterPro:IPR005793" /db_xref="InterPro:IPR005794" /db_xref="InterPro:IPR011034" /db_xref="InterPro:IPR036477" /db_xref="InterPro:IPR037022" /db_xref="SubtiList:BG11937" /db_xref="UniProtKB/Swiss-Prot:P94463" /translation="MTRIVFMGTPDFSVPVLRTLIEDGYEVVGVVTQPDRPKGRKKVL TPPPVKEEALRHGIPVLQPEKVRLTEEIEKVLALKPDLIVTAAFGQILPKELLDSPKY GCINVHASLLPELRGGAPIHYSILQGKKKTGITIMYMVEKLDAGDMISKVEVDIEETD NVGTLHDKLSVAGAKLLSETVPNVIAGSISPEKQDEEKATYAPNIKREQELLDWSRTG EELYNQIRGLNPWPVAYTTLNGQNLKIWASKKIAAPTTAEPGTVVAVEKEGIIVATGN ETALLLTELQPAGKKRMKGEDFVRGAHVEAGDVLGVNNEKN*" gene 1646999..1647952 /gene="fmt" /locus_tag="BSU_15730" /old_locus_tag="BSU15730" CDS 1647939..1649282 /gene="rsmB" /locus_tag="BSU_15740" /old_locus_tag="BSU15740" /EC_number="2.1.1.176" /function="16.6: Maintain" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 14656444, 23729652, 27698115; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="RNA-binding Sun protein; 16S rRNA m5C967 methyltransferase, S-adenosyl-L-methionine-dependent" /protein_id="NP_389456.1" /db_xref="EnsemblGenomes-Gn:BSU15740" /db_xref="EnsemblGenomes-Tr:CAB13447" /db_xref="GOA:P94464" /db_xref="InterPro:IPR001678" /db_xref="InterPro:IPR004573" /db_xref="InterPro:IPR006027" /db_xref="InterPro:IPR018314" /db_xref="InterPro:IPR023267" /db_xref="InterPro:IPR029063" /db_xref="InterPro:IPR035926" /db_xref="SubtiList:BG12253" /db_xref="UniProtKB/Swiss-Prot:P94464" /translation="MKKTSVRDIALEALIKLEQNQAYSNLLLKSVIKSNELSDQNRGL LTELVYGTLQNKIALDYMLKPFINKPQKVKPWVIQLLRLSLYQMEYLEKIPDRAAIHE AVEIAKIRGHKGIASFVNGVLRSIQREGVPSFDAIEDPVRRLATETSHPEWLVKEWAD AYGFEAAEKICRIHLIPPKQTLRVNQMKADRAELLDQMAAEGIEVEKGDLAEDAVKLL KGTIAGTHFFQNGEVSIQDESSMLVARALDPKSDETVLDACAAPGGKSAHIAELMKNK GSVTSLDLHKHKVKLIKEAADRLGLTIIHAETMDARKAGETFENEQFDRILVDAPCSG FGVIRRKPDMKYTKKPDDSARLAEIQLSILREIAPLVKKGGTLVYSTCTMDRTENDEV IHAFIQEHPDFEPDLSLEKRLPEKVRPFVRDGRLQILPHYFGTDGFFICSMRKKG*" gene 1647939..1649282 /gene="rsmB" /locus_tag="BSU_15740" /old_locus_tag="BSU15740" CDS 1649286..1650377 /gene="rlmN" /locus_tag="BSU_15750" /old_locus_tag="BSU15750" /EC_number="2.1.1.192" /function="10.3: tRNA and rRNA base modification" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 8973346, 18307109, 20184321, 21368151, 22891362, 27081063, 27902775; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="23S rRNA m2A2503 methyltransferase and tRNA A37 C2 methyltransferase" /protein_id="NP_389457.1" /db_xref="EnsemblGenomes-Gn:BSU15750" /db_xref="EnsemblGenomes-Tr:CAB13448" /db_xref="GOA:O34617" /db_xref="InterPro:IPR004383" /db_xref="InterPro:IPR007197" /db_xref="InterPro:IPR013785" /db_xref="InterPro:IPR027492" /db_xref="SubtiList:BG13389" /db_xref="UniProtKB/Swiss-Prot:O34617" /translation="MAELNKTKVRKELRTERPSIYSFELDEIKQWLTDNGEKPFRAAQ IFEWLYEKRVSSFEDMTNLSKDLREKLNTRFVLTTLKTAVKQTSQDGTMKFLFELHDG YTIETVLMRHEYGNSVCVTTQVGCRIGCTFCASTLGGLKRNLEAGEIVAQVVKVQKAL DETDERVSSVVIMGIGEPFDNFNEMLAFLKIINHDKGLNIGARHITVSTSGIIPKIYE FADQQMQINFAISLHAPNTEIRSRLMPINRAYKLPDLMEAVKYYINKTGRRISFEYGL FGGVNDQVEHAEELADLLEGVKCHVNLIPVNYVPERDYVRTPRDQIFAFEKTLKSRGV NVTIRREQGHDIDAACGQLRAKERQDETR*" gene 1649286..1650377 /gene="rlmN" /locus_tag="BSU_15750" /old_locus_tag="BSU15750" CDS 1650384..1651148 /gene="prpC" /locus_tag="BSU_15760" /old_locus_tag="BSU15760" /EC_number="3.1.3.16" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:10986276, 12399479, 17693724, 22720735, 24390483, 25012659" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10986276, 12399479, 17693724, 22720735, 24390483, 25012659; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="multitarget phosphorylated protein phosphatase" /protein_id="NP_389458.1" /db_xref="EnsemblGenomes-Gn:BSU15760" /db_xref="EnsemblGenomes-Tr:CAB13449" /db_xref="GOA:O34779" /db_xref="InterPro:IPR001932" /db_xref="InterPro:IPR015655" /db_xref="InterPro:IPR036457" /db_xref="SubtiList:BG13390" /db_xref="UniProtKB/Swiss-Prot:O34779" /translation="MLTALKTDTGKIRQHNEDDAGIFKGKDEFILAVVADGMGGHLAG DVASKMAVKAMGEKWNEAETIPTAPSECEKWLIEQILSVNSKIYDHAQAHEECQGMGT TIVCALFTGKTVSVAHIGDSRCYLLQDDDFVQVTEDHSLVNELVRTGEISREDAEHHP RKNVLTKALGTDQLVSIDTRSFDIEPGDKLLLCSDGLTNKVEGTELKDILQSDSAPQE KVNLLVDKANQNGGEDNITAVLLELALQVEEGEDQC*" gene 1650384..1651148 /gene="prpC" /locus_tag="BSU_15760" /old_locus_tag="BSU15760" downshifts 1650437 /Source="Nicolas_upshifts" /id="D878" /incds=0 /nref=5 /ntot=126 /MaxReadThrough="6.12318" /MaxDrop="3.8594" /score="-7.80200272" /energy="-10" /TU="U1295,U1298" /idTUdmin="U1300" /TUdmin="-4708" /isTUend="FALSE" CDS 1651142..1653088 /gene="prkC" /locus_tag="BSU_15770" /old_locus_tag="BSU15770" /EC_number="2.7.11.1" /function="16.3: Control" /function="16.12: Sense" /experiment="publication(s) with functional evidences, PMID:10986276, 12399479, 18984160, 24390483, 25845974, 26102633" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10986276, 12399479, 18984160, 24390483, 25845974, 26102633; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="protein serine/threonine kinase" /protein_id="NP_389459.1" /db_xref="EnsemblGenomes-Gn:BSU15770" /db_xref="EnsemblGenomes-Tr:CAB13450" /db_xref="GOA:O34507" /db_xref="InterPro:IPR000719" /db_xref="InterPro:IPR005543" /db_xref="InterPro:IPR008271" /db_xref="InterPro:IPR011009" /db_xref="InterPro:IPR017441" /db_xref="SubtiList:BG13391" /db_xref="UniProtKB/Swiss-Prot:O34507" /translation="MLIGKRISGRYQILRVIGGGGMANVYLAEDIILDREVAIKILRF DYANDNEFIRRFRREAQSASSLDHPNIVSIYDLGEEDDIYYIVMEYVEGMTLKEYITA NGPLHPKEALNIMEQIVSAIAHAHQNQIVHRDIKPHNILIDHMGNIKVTDFGIATALS STTITHTNSVLGSVHYLSPEQARGGLATKKSDIYALGIVLFELLTGRIPFDGESAVSI ALKHLQAETPSAKRWNPSVPQSVENIILKATAKDPFHRYETAEDMEADIKTAFDADRL NEKRFTIQEDEEMTKAIPIIKDEELAKAAGEKEAEVTTAQENKTKKNGKRKKWPWVLL TICLVFITAGILAVTVFPSLFMPKDVKIPDVSGMEYEKAAGLLEKEGLQVDSEVLEIS DEKIEEGLMVKTDPKADTTVKEGATVTLYKSTGKAKTEIGDVTGQTVDQAKKALKDQG FNHVTVNEVNDEKNAGTVIDQNPSAGTELVPSEDQVKLTVSIGPEDITLRDLKTYSKE AASGYLEDNGLKLVEKEAYSDDVPEGQVVKQKPAAGTAVKPGNEVEVTFSLGPEKKPA KTVKEKVKIPYEPENEGDELQVQIAVDDADHSISDTYEEFKIKEPTERTIELKIEPGQ KGYYQVMVNNKVVSYKTIEYPKDE*" gene 1651142..1653088 /gene="prkC" /locus_tag="BSU_15770" /old_locus_tag="BSU15770" promotor_-35 1652997..1653003 /Source="Nicolas_upshift_promotors" /id="U1299" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.973026973026973" /psig="0.973026973026973" /xcortree=173 /SigmaFactorBS="cgactgaacgaacgatcgaactaaAGATTGAaccaggccaaa aaGGGTACTATCAAGTAATGGtaaacaataaagttgtcagctacaaaaccattgagta t" /listShort="cpgA, rpe, thiN, S573, spoVM" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1653017..1653035 /Source="Nicolas_upshift_promotors" /id="U1299" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.973026973026973" /psig="0.973026973026973" /xcortree=173 /SigmaFactorBS="cgactgaacgaacgatcgaactaaAGATTGAaccaggccaaa aaGGGTACTATCAAGTAATGGtaaacaataaagttgtcagctacaaaaccattgagta t" /listShort="cpgA, rpe, thiN, S573, spoVM" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1653033 /Source="Nicolas_upshifts" /id="U1299" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.973026973026973" /psig="0.973026973026973" /xcortree=173 /SigmaFactorBS="cgactgaacgaacgatcgaactaaAGATTGAaccaggccaaa aaGGGTACTATCAAGTAATGGtaaacaataaagttgtcagctacaaaaccattgagta t" /listShort="cpgA, rpe, thiN, S573, spoVM" /GFF_Attribute="listLong" CDS 1653103..1653999 /gene="rsgA" /locus_tag="BSU_15780" /old_locus_tag="BSU15780" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:15223319, 15828870, 16014871, 16485133, 17005971, 18007041, 18344364, 19246764, 22544754, 22720735, 28482099" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15223319, 15828870, 16014871, 16485133, 17005971, 18007041, 18344364, 19246764, 22544754, 22720735, 28482099; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="GTPase involved in ribosome biogenesis" /protein_id="NP_389460.1" /db_xref="EnsemblGenomes-Gn:BSU15780" /db_xref="EnsemblGenomes-Tr:CAB13451" /db_xref="GOA:O34530" /db_xref="InterPro:IPR004881" /db_xref="InterPro:IPR010914" /db_xref="InterPro:IPR012340" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR030378" /db_xref="InterPro:IPR031944" /db_xref="PDB:1T9H" /db_xref="SubtiList:BG13392" /db_xref="UniProtKB/Swiss-Prot:O34530" /translation="MPEGKIIKALSGFYYVLDESEDSDKVIQCRGRGIFRKNKITPLV GDYVVYQAENDKEGYLMEIKERTNELIRPPICNVDQAVLVFSAVQPSFSTALLDRFLV LVEANDIQPIICITKMDLIEDQDTEDTIQAYAEDYRNIGYDVYLTSSKDQDSLADIIP HFQDKTTVFAGQSGVGKSSLLNAISPELGLRTNEISEHLGRGKHTTRHVELIHTSGGL VADTPGFSSLEFTDIEEEELGYTFPDIREKSSSCKFRGCLHLKEPKCAVKQAVEDGEL KQYRYDHYVEFMTEIKDRKPRY*" gene 1653103..1653999 /gene="rsgA" /locus_tag="BSU_15780" /old_locus_tag="BSU15780" CDS 1654004..1654657 /gene="rpe" /locus_tag="BSU_15790" /old_locus_tag="BSU15790" /EC_number="5.1.3.1" /function="16.2: Construct biomass (Anabolism)" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 973353, 15755726, 16489742, 22720735; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="ribulose-5-phosphate 3-epimerase" /protein_id="NP_389461.1" /db_xref="EnsemblGenomes-Gn:BSU15790" /db_xref="EnsemblGenomes-Tr:CAB13452" /db_xref="GOA:O34557" /db_xref="InterPro:IPR000056" /db_xref="InterPro:IPR011060" /db_xref="InterPro:IPR013785" /db_xref="InterPro:IPR026019" /db_xref="SubtiList:BG13393" /db_xref="UniProtKB/Swiss-Prot:O34557" /translation="MIKVAPSILSADFAALGNEIKDVEKGGADCIHIDVMDGHFVPNI TIGPLIVEAVRPVTDLPLDVHLMIEEPDRYIPAFAKAGADILSVHAEACPHLHRTIQL IKEQGVKAGVVLNPHTPVQVIEHVFDDLDLVLLMTVNPGFGGQKFIHSVLPKIKEVKR MADEKGKKDLLIEVDGGVNKETAPLVIEAGANLLVAGSAVYGQSDRKKAISEIRGSK* " gene 1654004..1654657 /gene="rpe" /locus_tag="BSU_15790" /old_locus_tag="BSU15790" promotor_-35 1654655..1654664 /Source="Nicolas_upshift_promotors" /id="U1300" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.95104895104895" /psig="0.95104895104895" /xcortree=753 /SigmaFactorBS="aaaaagcaatttctgaaatcagaggaagtaaaTAAGCAGCTT tagaaaagagctgGGCATACAATAGCCTAAGCTctttttcctgtatgcagagaaagga a" /listShort="thiN" /listLong="S573, spoVM, S574, yloU, yloV" /label="promotor_-35" promotor_-10 1654678..1654697 /Source="Nicolas_upshift_promotors" /id="U1300" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.95104895104895" /psig="0.95104895104895" /xcortree=753 /SigmaFactorBS="aaaaagcaatttctgaaatcagaggaagtaaaTAAGCAGCTT tagaaaagagctgGGCATACAATAGCCTAAGCTctttttcctgtatgcagagaaagga a" /listShort="thiN" /listLong="S573, spoVM, S574, yloU, yloV" /label="promotor_-10" upshifts 1654683 /Source="Nicolas_upshifts" /id="U1300" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.95104895104895" /psig="0.95104895104895" /xcortree=753 /SigmaFactorBS="aaaaagcaatttctgaaatcagaggaagtaaaTAAGCAGCTT tagaaaagagctgGGCATACAATAGCCTAAGCTctttttcctgtatgcagagaaagga a" /listShort="thiN" /listLong="S573, spoVM, S574, yloU, yloV" CDS 1654730..1655374 /gene="thiN" /locus_tag="BSU_15800" /old_locus_tag="BSU15800" /EC_number="2.7.6.2" /function="16.2: Construct biomass (Anabolism)" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 14567704, 15150256, 16291685, 19490098; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="thiamine pyrophosphokinase" /protein_id="NP_389462.1" /db_xref="EnsemblGenomes-Gn:BSU15800" /db_xref="EnsemblGenomes-Tr:CAB13453" /db_xref="GOA:O34664" /db_xref="InterPro:IPR006282" /db_xref="InterPro:IPR007371" /db_xref="InterPro:IPR007373" /db_xref="InterPro:IPR036371" /db_xref="InterPro:IPR036759" /db_xref="PDB:3LM8" /db_xref="SubtiList:BG13394" /db_xref="UniProtKB/Swiss-Prot:O34664" /translation="MKTINIVAGGPKNLIPDLTGYTDEHTLWIGVDKGTVTLLDAGII PVEAFGDFDSITEQERRRIEKAAPALHVYQAEKDQTDLDLALDWALEKQPDIIQIFGI TGGRADHFLGNIQLLYKGVKTNIKIRLIDKQNHIQMFPPGEYDIEKDENKRYISFIPF SEDIHELTLTGFKYPLNNCHITLGSTLCISNELIHSRGTFSFAKGILIMIRSTD*" gene 1654730..1655374 /gene="thiN" /locus_tag="BSU_15800" /old_locus_tag="BSU15800" promotor_-35 1655135..1655141 /Source="Nicolas_upshift_promotors" /id="U1301" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.548451548451548" /psig="0.548451548451548" /xcortree=1059 /SigmaFactorBS="aaaaacgaacataaaaattaggctgatagacaaacaaaatca tATTCAAAtgttccctcctggtGAATATGATATTGAGAAGGatgaaaataagcgatat a" /listShort="S573, spoVM, S574" /listLong="yloU, yloV" /label="promotor_-35" upshifts 1655152 /Source="Nicolas_upshifts" /id="U1301" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.548451548451548" /psig="0.548451548451548" /xcortree=1059 /SigmaFactorBS="aaaaacgaacataaaaattaggctgatagacaaacaaaatca tATTCAAAtgttccctcctggtGAATATGATATTGAGAAGGatgaaaataagcgatat a" /listShort="S573, spoVM, S574" /listLong="yloU, yloV" promotor_-10 1655156..1655174 /Source="Nicolas_upshift_promotors" /id="U1301" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.548451548451548" /psig="0.548451548451548" /xcortree=1059 /SigmaFactorBS="aaaaacgaacataaaaattaggctgatagacaaacaaaatca tATTCAAAtgttccctcctggtGAATATGATATTGAGAAGGatgaaaataagcgatat a" /listShort="S573, spoVM, S574" /listLong="yloU, yloV" /label="promotor_-10" promotor_-35 1655265..1655270 /Source="Nicolas_upshift_promotors" /id="U1302" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.977022977022977" /psig="0.977022977022977" /xcortree=1088 /SigmaFactorBS="cggttttaaatatcctctaaataattGTCATAttacgctcgg ttcaaCACTATGTATTAGTAACGAactcattcattcacgaggtactttttcgtttgca a" /listShort="S573, spoVM, S574, yloU, yloV" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1655286..1655304 /Source="Nicolas_upshift_promotors" /id="U1302" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.977022977022977" /psig="0.977022977022977" /xcortree=1088 /SigmaFactorBS="cggttttaaatatcctctaaataattGTCATAttacgctcgg ttcaaCACTATGTATTAGTAACGAactcattcattcacgaggtactttttcgtttgca a" /listShort="S573, spoVM, S574, yloU, yloV" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1655299 /Source="Nicolas_upshifts" /id="U1302" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.977022977022977" /psig="0.977022977022977" /xcortree=1088 /SigmaFactorBS="cggttttaaatatcctctaaataattGTCATAttacgctcgg ttcaaCACTATGTATTAGTAACGAactcattcattcacgaggtactttttcgtttgca a" /listShort="S573, spoVM, S574, yloU, yloV" /GFF_Attribute="listLong" S_feature 1655375..1655445 /Source="Nicolas_S_feature" /locus_tag="new_1655375_1655445" /HighExp="S4, S5, S7, S8, S6, S3, B36, G/S, B60, BT" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigEF, SigEF, SigB, SigA, SigA" /TUshortPSig="0.977, 0.548, 0.973, 1, 0.994" /TUlongSig="SigK" /TUlongPSig="0.951" /label="S573" CDS 1655446..1655526 /gene="spoVM" /locus_tag="BSU_15810" /old_locus_tag="BSU15810" /function="16.8: Protect" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:9922240, 10077851, 10913836, 12562810, 18820968, 25825747, 28408070" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9922240, 10077851, 10913836, 12562810, 18820968, 25825747, 28408070; Product type f: factor" /codon_start=1 /transl_table=11 /product="factor required for normal spore cortex and coatsynthesis (stage V sporulation)" /protein_id="NP_389463.1" /db_xref="EnsemblGenomes-Gn:BSU15810" /db_xref="EnsemblGenomes-Tr:CAB13454" /db_xref="GOA:P37817" /db_xref="InterPro:IPR012609" /db_xref="PDB:2MVH" /db_xref="PDB:2MVJ" /db_xref="SubtiList:BG10776" /db_xref="UniProtKB/Swiss-Prot:P37817" /translation="MKFYTIKLPKFLGGIVRAMLGSFRKD*" gene 1655446..1655526 /gene="spoVM" /locus_tag="BSU_15810" /old_locus_tag="BSU15810" downshifts 1655541 /Source="Nicolas_upshifts" /id="D879" /incds=0 /nref=178 /ntot=258 /MaxReadThrough="4.05442" /MaxDrop="7.745" /score="7.47691609" /energy="-16.9" /TU="U1301,U1302" /idTUdmin="U1295" /TUdmin=0 /isTUend="TRUE" S_feature 1655586..1655958 /Source="Nicolas_S_feature" /locus_tag="new_1655586_1655958" /HighExp="S4, S5, T5.0H, S3, S6, S8, S7, T4.0H, LoTm, T3.30H" /AntisenseName="rpmB" /AntisenseCor="-0.40376097579549802" /AntisenseRegPval="-11.2" /CDS_PredictionProba="NA" /TUshortSig="SigEF, SigEF" /TUshortPSig="0.977, 0.548" /TUlongSig="SigK" /TUlongPSig="0.951" /label="S574" CDS complement(1655599..1655787) /gene="rpmB" /locus_tag="BSU_15820" /old_locus_tag="BSU15820" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1c: Function from experimental evidences in the studied genus; PubMedId: 8722036; Product type f : factor" /codon_start=1 /transl_table=11 /product="ribosomal protein L28" /protein_id="NP_389464.1" /db_xref="EnsemblGenomes-Gn:BSU15820" /db_xref="EnsemblGenomes-Tr:CAB13455" /db_xref="GOA:P37807" /db_xref="InterPro:IPR001383" /db_xref="InterPro:IPR026569" /db_xref="InterPro:IPR034704" /db_xref="InterPro:IPR037147" /db_xref="PDB:3J9W" /db_xref="PDB:5NJT" /db_xref="SubtiList:BG10777" /db_xref="UniProtKB/Swiss-Prot:P37807" /translation="MARKCVITGKKTTAGNNRSHAMNASKRTWGANLQKVRILVNGKP KKVYVSARALKSGKVERV*" gene complement(1655599..1655787) /gene="rpmB" /locus_tag="BSU_15820" /old_locus_tag="BSU15820" downshifts complement(1655615) /Source="Nicolas_upshifts" /id="D880" /incds=0 /nref=216 /ntot=298 /MaxReadThrough="2.59598" /MaxDrop="7.48719" /score="15.2403969" /energy="-14.3" /TU="NA" /idTUdmin="U1303" /TUdmin="-20" /isTUend="TRUE" downshifts complement(1655661) /Source="Nicolas_upshifts" /id="D881" /incds=1 /nref=1 /ntot=18 /MaxReadThrough="7.6779" /MaxDrop="3.1786" /score="15.2403969" /energy="-14.3" /TU="U1303" /idTUdmin="U1303" /TUdmin="-66" /isTUend="FALSE" S_feature complement(1655788..1655880) /Source="Nicolas_S_feature" /locus_tag="new_1655788_1655880_c" /HighExp="HPh, LPh, HiOs, LBGexp, aero, G180, GM 15, dia0, MG 25, MG t5" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S575" promotor_-10 complement(1655862..1655881) /Source="Nicolas_upshift_promotors" /id="U1303" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.782217782217782" /psig=1 /xcortree=2637 /SigmaFactorBS="agatgtcaagtgaattttcttgaaagatgatgaaacaataGT TGcaaacgttttttagcTGTGGTAAATTATTTAAAGTatccatatcgaaagcatctaa g" /listShort="S575, rpmB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1655880) /Source="Nicolas_upshifts" /id="U1303" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.782217782217782" /psig=1 /xcortree=2637 /SigmaFactorBS="agatgtcaagtgaattttcttgaaagatgatgaaacaataGT TGcaaacgttttttagcTGTGGTAAATTATTTAAAGTatccatatcgaaagcatctaa g" /listShort="S575, rpmB" /GFF_Attribute="listLong" promotor_-35 complement(1655897..1655900) /Source="Nicolas_upshift_promotors" /id="U1303" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.782217782217782" /psig=1 /xcortree=2637 /SigmaFactorBS="agatgtcaagtgaattttcttgaaagatgatgaaacaataGT TGcaaacgttttttagcTGTGGTAAATTATTTAAAGTatccatatcgaaagcatctaa g" /listShort="S575, rpmB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1655931..1655938 /Source="Nicolas_upshift_promotors" /id="U1304" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.54045954045954" /psig="0.99100899100899" /xcortree=2309 /SigmaFactorBS="ctattgtttcatcatctttcaagaaaattcaCTTGACATctt gcggaaacagcAGCGCTATAGTATATGTAGaggtacggccagcgattattgcctggtc t" /listShort="yloU, yloV, S576, sdaAB, sdaAA, recG" /listLong="fapR, plsX, fabD, fabG, acpA, S577, rnc, smc, ftsY" /label="promotor_-35" promotor_-10 1655953..1655971 /Source="Nicolas_upshift_promotors" /id="U1304" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.54045954045954" /psig="0.99100899100899" /xcortree=2309 /SigmaFactorBS="ctattgtttcatcatctttcaagaaaattcaCTTGACATctt gcggaaacagcAGCGCTATAGTATATGTAGaggtacggccagcgattattgcctggtc t" /listShort="yloU, yloV, S576, sdaAB, sdaAA, recG" /listLong="fapR, plsX, fabD, fabG, acpA, S577, rnc, smc, ftsY" /label="promotor_-10" upshifts 1655960 /Source="Nicolas_upshifts" /id="U1304" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.54045954045954" /psig="0.99100899100899" /xcortree=2309 /SigmaFactorBS="ctattgtttcatcatctttcaagaaaattcaCTTGACATctt gcggaaacagcAGCGCTATAGTATATGTAGaggtacggccagcgattattgcctggtc t" /listShort="yloU, yloV, S576, sdaAB, sdaAA, recG" /listLong="fapR, plsX, fabD, fabG, acpA, S577, rnc, smc, ftsY" promotor_-35 1655999..1656002 /Source="Nicolas_upshift_promotors" /id="U1305" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.451548451548452" /psig="0.99100899100899" /xcortree=2326 /SigmaFactorBS="tatgtagaggtacggccagcgattattgcctggtCTTTtcat aatggaaaccATATAGTAGAATAGCTGTAActctatgcattcgaaggaggaactagtg t" /listShort="yloU, yloV, S576, sdaAB, sdaAA, recG" /listLong="fapR, plsX, fabD, fabG, acpA, S577, rnc, smc, ftsY" /label="promotor_-35" promotor_-10 1656017..1656036 /Source="Nicolas_upshift_promotors" /id="U1305" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.451548451548452" /psig="0.99100899100899" /xcortree=2326 /SigmaFactorBS="tatgtagaggtacggccagcgattattgcctggtCTTTtcat aatggaaaccATATAGTAGAATAGCTGTAActctatgcattcgaaggaggaactagtg t" /listShort="yloU, yloV, S576, sdaAB, sdaAA, recG" /listLong="fapR, plsX, fabD, fabG, acpA, S577, rnc, smc, ftsY" /label="promotor_-10" upshifts 1656025 /Source="Nicolas_upshifts" /id="U1305" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.451548451548452" /psig="0.99100899100899" /xcortree=2326 /SigmaFactorBS="tatgtagaggtacggccagcgattattgcctggtCTTTtcat aatggaaaccATATAGTAGAATAGCTGTAActctatgcattcgaaggaggaactagtg t" /listShort="yloU, yloV, S576, sdaAB, sdaAA, recG" /listLong="fapR, plsX, fabD, fabG, acpA, S577, rnc, smc, ftsY" CDS 1656064..1656426 /gene="yloU" /locus_tag="BSU_15830" /old_locus_tag="BSU15830" /function="16.2: Construct biomass (Anabolism)" /function="16.3: Control" /function="16.13: Shape" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 16014871, 17114254, 24178028, 28579978; Product type f: factor" /codon_start=1 /transl_table=11 /product="putative factor involved in malonyl-CoA synthesis" /protein_id="NP_389465.1" /db_xref="EnsemblGenomes-Gn:BSU15830" /db_xref="EnsemblGenomes-Tr:CAB13456" /db_xref="InterPro:IPR005531" /db_xref="InterPro:IPR036837" /db_xref="SubtiList:BG13395" /db_xref="UniProtKB/Swiss-Prot:O34318" /translation="MSIELRTKYGQIDISNEVIAMVAGGAAVDCYGIVGMASKNQIKD GLTEILRKENFSRGVQVRQEGEQIHIDMYIIVSYGTKISEVAHNVQTKVKYTVNQTIG LAVDSVNIYVQGVRVTNP*" gene 1656064..1656426 /gene="yloU" /locus_tag="BSU_15830" /old_locus_tag="BSU15830" downshifts complement(1656277) /Source="Nicolas_upshifts" /id="D882" /incds=1 /nref=1 /ntot=143 /MaxReadThrough="1.75412" /MaxDrop="2.71497" /score="15.2403969" /energy="-14.3" /TU="NA" /idTUdmin="U1303" /TUdmin="-682" /isTUend="FALSE" CDS 1656442..1658103 /gene="yloV" /locus_tag="BSU_15840" /old_locus_tag="BSU15840" /EC_number="2.7.-.-" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 16647083, 22333191, 22517742; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative enzyme structurally related to dihydroxyacetone/glyceraldehyde kinase" /protein_id="NP_389466.1" /db_xref="EnsemblGenomes-Gn:BSU15840" /db_xref="EnsemblGenomes-Tr:CAB13457" /db_xref="GOA:O34751" /db_xref="InterPro:IPR004007" /db_xref="InterPro:IPR019986" /db_xref="InterPro:IPR033470" /db_xref="InterPro:IPR036117" /db_xref="SubtiList:BG13396" /db_xref="UniProtKB/Swiss-Prot:O34751" /translation="MSIRTLDGRTFAEMILAGAQNLSQNASAVDALNVFPVPDGDTGT NMNLSMTSGAREVEQMDTDDIGKVGSALSKGLLMGARGNSGVILSQLFRGFSKNIETK KEINALEFAAALQAGVDMAYKAVMKPVEGTILTVAKDAAKKAMILAEKETDITALMTA VTEEAEASLNRTPELLPVLKEVGVVDSGGKGLLCVYEGFLASLKGETVPQKAVLPSLD DMVSAEHHKSAQSMMNTEDIEFGFCTEVMVRLDQTKREFDEGTFRQDLSQFGDSLLVI ADESLAKVHIHAEEPGNVLNYAQHYGELIKIKIENMREQHTSIISQESKPADNETPPA KQPYGIVTVAMGEGIADLFKSIGASVVIEGGQTMNPSTEDIVDAVKSVNADTVFILPN NSNIIMAANQAASVVDEQVFVIPAKTVPQGMSALLAFNPDQEAEANEANMLSAIQQVK SGQVTFSVRDTHIDGKDIKKGDFMGILNGTIIGTSENQLSAAKMLLSEMIGEDDEIVT ILYGEDASQEEAEQLEAFLSEKYEEIEVEIHNGKQPLYSYIVSAE*" gene 1656442..1658103 /gene="yloV" /locus_tag="BSU_15840" /old_locus_tag="BSU15840" S_feature 1658104..1658193 /Source="Nicolas_S_feature" /locus_tag="new_1658104_1658193" /HighExp="G135, G180, G150, LBGexp, Oxctl, Paraq, dia0, LPh, Lbexp, S0" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.37023200000000001" /TUshortSig="SigA, SigA" /TUshortPSig="0.991, 0.991" /TUlongSig="NA" /TUlongPSig="NA" /label="S576" promotor_-35 1658166..1658173 /Source="Nicolas_upshift_promotors" /id="U1306" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.663336663336663" /psig="0.999000999001" /xcortree=385 /SigmaFactorBS="gcttttaagtgcggcagcgctgtaacgcgccCGCTTGCCatt ttatatctgaTCAATTAGTCTAGAAGCAAAgcgctaataagctctggttcataaggag g" /listShort="sdaAB, sdaAA, recG, fapR, plsX, fabD, fabG, acpA, S577, rnc" /listLong="smc, ftsY" /label="promotor_-35" promotor_-10 1658187..1658206 /Source="Nicolas_upshift_promotors" /id="U1306" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.663336663336663" /psig="0.999000999001" /xcortree=385 /SigmaFactorBS="gcttttaagtgcggcagcgctgtaacgcgccCGCTTGCCatt ttatatctgaTCAATTAGTCTAGAAGCAAAgcgctaataagctctggttcataaggag g" /listShort="sdaAB, sdaAA, recG, fapR, plsX, fabD, fabG, acpA, S577, rnc" /listLong="smc, ftsY" /label="promotor_-10" upshifts 1658195 /Source="Nicolas_upshifts" /id="U1306" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.663336663336663" /psig="0.999000999001" /xcortree=385 /SigmaFactorBS="gcttttaagtgcggcagcgctgtaacgcgccCGCTTGCCatt ttatatctgaTCAATTAGTCTAGAAGCAAAgcgctaataagctctggttcataaggag g" /listShort="sdaAB, sdaAA, recG, fapR, plsX, fabD, fabG, acpA, S577, rnc" /listLong="smc, ftsY" CDS 1658242..1658904 /gene="sdaAB" /locus_tag="BSU_15850" /old_locus_tag="BSU15850" /EC_number="4.3.1.17" /function="16.8: Protect" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:8385012, 9244285, 16014871, 22686449" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8385012, 9244285, 16014871, 22686449; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="L-serine dehydratase (beta chain)" /protein_id="NP_389467.1" /db_xref="EnsemblGenomes-Gn:BSU15850" /db_xref="EnsemblGenomes-Tr:CAB13458" /db_xref="GOA:O34635" /db_xref="InterPro:IPR002912" /db_xref="InterPro:IPR004643" /db_xref="InterPro:IPR005131" /db_xref="InterPro:IPR029009" /db_xref="SubtiList:BG13397" /db_xref="UniProtKB/Swiss-Prot:O34635" /translation="MKYRSVFDIIGPVMIGPSSSHTAGAARIGRVARSLFGREPERII VSFYGSFAETYKGHGTDVAIIGGLLDFDTFDERIKTAIQIAEAKGIDIEFRVEDAVPV HPNTAKITISDEKGELELTGISIGGGKIEITELNGFELRLSGNHPAILVVHNDKFGTI AGVANVLAKFSINVGHMEVARKDIGQLALMTIEVDQNIDDHILDELSKLPNIIQVTKI AD*" gene 1658242..1658904 /gene="sdaAB" /locus_tag="BSU_15850" /old_locus_tag="BSU15850" CDS 1658930..1659832 /gene="sdaAA" /locus_tag="BSU_15860" /old_locus_tag="BSU15860" /EC_number="4.3.1.17" /function="16.8: Protect" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:2504697, 16014871, 22686449" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 2504697, 16014871, 22686449; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="L-serine dehydratase (alpha chain)" /protein_id="NP_389468.1" /db_xref="EnsemblGenomes-Gn:BSU15860" /db_xref="EnsemblGenomes-Tr:CAB13459" /db_xref="GOA:O34607" /db_xref="InterPro:IPR004642" /db_xref="InterPro:IPR005130" /db_xref="SubtiList:BG13398" /db_xref="UniProtKB/Swiss-Prot:O34607" /translation="MFRNVKELIEITKEKQILISDVMIAQEMEVTEKTKEDIFQQMDH NLSVMEAAVQKGLEGVTSQTGLTGGDAVKLQAYIRSGKSLSGPLILDAVSKAVATNEV NAAMGTICATPTAGSAGVVPGTLFAVKEKLNPTREQMIRFLFTAGAFGFVVANNASIS GAAGGCQAEVGSASGMAAAAIVEMAGGTPEQSAEAMAITLKNMLGLVCDPVAGLVEVP CVKRNAMGASNAMIAADMALAGITSRIPCDEVIDAMYKIGQTMPTALRETGQGGLAAT PTGRELEKKIFGGALGSRETTSAN*" gene 1658930..1659832 /gene="sdaAA" /locus_tag="BSU_15860" /old_locus_tag="BSU15860" CDS 1659810..1661858 /gene="recG" /locus_tag="BSU_15870" /old_locus_tag="BSU15870" /EC_number="3.6.4.12" /function="16.6: Maintain" /function="16.9: Replicate" /experiment="publication(s) with functional evidences, PMID:1905712, 1494351, 15317759, 15533834, 16014871, 28078722, 28155219, 28527403" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1905712, 1494351, 15317759, 15533834, 16014871, 28078722, 28155219, 28527403; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="branch migrating ATP-dependent DNA helicase involved in DNA recombination and repair" /protein_id="NP_389469.1" /db_xref="EnsemblGenomes-Gn:BSU15870" /db_xref="EnsemblGenomes-Tr:CAB13460" /db_xref="GOA:O34942" /db_xref="InterPro:IPR001650" /db_xref="InterPro:IPR004609" /db_xref="InterPro:IPR011545" /db_xref="InterPro:IPR012340" /db_xref="InterPro:IPR014001" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR033454" /db_xref="SubtiList:BG13399" /db_xref="UniProtKB/Swiss-Prot:O34942" /translation="MKQHQQTSIANIKGIGPETEKTLNELGIYDISDLLNYFPYRYDD YELRDLEEVKHDERVTVEGKVHSEPSLTYYGKKRNRLTFRLLVGHYLITAVCFNRPYL KKKLSLGSVVTVSGKWDKHRQTISVQELKNGPHQEDKSIEPVYSVKENVTVKMMRRFI QQALTQYADSLPDPLPEKLRKSYKLPDYYQALKAMHQPETREALKLARRRFVYEEFLL FQLKMQAFRKAEREQTQGIRQRFSNEELMRFIKSLPFPLTNAQSRVLREITADMSSPY RMNRLLQGDVGSGKTAVAAIALYAAILSGYQGALMVPTEILAEQHADSLVSLFEKWDV SVALLTSSVKGKRRKELLERLAAGEIDILVGTHALIQDEVEFKALSLVITDEQHRFGV EQRKKLRNKGQDPDVLFMTATPIPRTLAITVFGEMDVSVIDEMPAGRKRIETYWVKHD MLDRILAFVEKELKQGRQAYIICPLIEESDKLDVQNAIDVYNMLSDIFRGKWNVGLMH GKLHSDEKDQVMREFSANHCQILVSTTVVEVGVNVPNATIMVIYDADRFGLSQLHQLR GRVGRGEHQSFCILMADPKSETGKERMRIMSETNDGFELSEKDLELRGPGDFFGKKQS GMPEFKVADMVHDYRALETARQDAANLVASDAFWKEPEYAVLRDELLKSGVMDGEKLS *" gene 1659810..1661858 /gene="recG" /locus_tag="BSU_15870" /old_locus_tag="BSU15870" promotor_-35 1661894..1661901 /Source="Nicolas_upshift_promotors" /id="U1307" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.522477522477522" /psig=1 /xcortree=2187 /SigmaFactorBS="tcagaagtttttggtgttcagccagaaacaatCGTTGCATtc caatctatgaaaTTATATACTACTATTAGTACctagtcttaattgtccggatggtgtt t" /listShort="fapR, plsX, fabD, fabG, acpA, S577, rnc, smc, ftsY" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1661916..1661935 /Source="Nicolas_upshift_promotors" /id="U1307" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.522477522477522" /psig=1 /xcortree=2187 /SigmaFactorBS="tcagaagtttttggtgttcagccagaaacaatCGTTGCATtc caatctatgaaaTTATATACTACTATTAGTACctagtcttaattgtccggatggtgtt t" /listShort="fapR, plsX, fabD, fabG, acpA, S577, rnc, smc, ftsY" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1661922 /Source="Nicolas_upshifts" /id="U1307" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.522477522477522" /psig=1 /xcortree=2187 /SigmaFactorBS="tcagaagtttttggtgttcagccagaaacaatCGTTGCATtc caatctatgaaaTTATATACTACTATTAGTACctagtcttaattgtccggatggtgtt t" /listShort="fapR, plsX, fabD, fabG, acpA, S577, rnc, smc, ftsY" /GFF_Attribute="listLong" CDS 1661967..1662533 /gene="fapR" /locus_tag="BSU_15880" /old_locus_tag="BSU15880" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:12737802, 17962296, 20201588, 22720735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12737802, 17962296, 20201588, 22720735; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcription factor controlling fatty acid and phospholipid metabolism (FapR-malonyl-Coa)" /protein_id="NP_389470.1" /db_xref="EnsemblGenomes-Gn:BSU15880" /db_xref="EnsemblGenomes-Tr:CAB13461" /db_xref="GOA:O34835" /db_xref="InterPro:IPR006683" /db_xref="InterPro:IPR017275" /db_xref="InterPro:IPR029069" /db_xref="InterPro:IPR036388" /db_xref="PDB:2F3X" /db_xref="PDB:2F41" /db_xref="SubtiList:BG13400" /db_xref="UniProtKB/Swiss-Prot:O34835" /translation="MRRNKRERQELLQQTIQATPFITDEELAGKFGVSIQTIRLDRLE LSIPELRERIKNVAEKTLEDEVKSLSLDEVIGEIIDLELDDQAISILEIKQEHVFSRN QIARGHHLFAQANSLAVAVIDDELALTASADIRFTRQVKQGERVVAKAKVTAVEKEKG RTVVEVNSYVGEEIVFSGRFDMYRSKHS*" gene 1661967..1662533 /gene="fapR" /locus_tag="BSU_15880" /old_locus_tag="BSU15880" CDS 1662547..1663548 /gene="plsX" /locus_tag="BSU_15890" /old_locus_tag="BSU15890" /function="16.13: Shape" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:8759840, 12682299, 16949372, 17557823, 17645809, 18369234, 19282621, 19850612, 24224907, 26816052, 26850107" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8759840, 12682299, 16949372, 17557823, 17645809, 18369234, 19282621, 19850612, 24224907, 26816052, 26850107; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="phosphate:acyl-ACP acyltransferase" /protein_id="NP_389471.1" /db_xref="EnsemblGenomes-Gn:BSU15890" /db_xref="EnsemblGenomes-Tr:CAB13462" /db_xref="GOA:P71018" /db_xref="InterPro:IPR003664" /db_xref="InterPro:IPR012281" /db_xref="PDB:1VI1" /db_xref="SubtiList:BG11843" /db_xref="UniProtKB/Swiss-Prot:P71018" /translation="MRIAVDAMGGDHAPKAVIDGVIKGIEAFDDLHITLVGDKTTIES HLTTTSDRITVLHADEVIEPTDEPVRAVRRKKNSSMVLMAQEVAENRADACISAGNTG ALMTAGLFIVGRIKGIDRPALAPTLPTVSGDGFLLLDVGANVDAKPEHLVQYAIMGSV YSQQVRGVTSPRVGLLNVGTEDKKGNELTKQTFQILKETANINFIGNVEARDLLDDVA DVVVTDGFTGNVTLKTLEGSALSIFKMMRDVMTSTLTSKLAAAVLKPKLKEMKMKMEY SNYGGASLFGLKAPVIKAHGSSDSNAVFHAIRQAREMVSQNVAALIQEEVKEEKTDE* " gene 1662547..1663548 /gene="plsX" /locus_tag="BSU_15890" /old_locus_tag="BSU15890" CDS 1663567..1664520 /gene="fabD" /locus_tag="BSU_15900" /old_locus_tag="BSU15900" /EC_number="2.3.1.39" /function="16.11: Scavenge (Catabolism)" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:12682299, 14586097, 19850612" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12682299, 14586097, 19850612; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="malonyl CoA:acyl carrier protein transacylase" /protein_id="NP_389472.1" /db_xref="EnsemblGenomes-Gn:BSU15900" /db_xref="EnsemblGenomes-Tr:CAB13463" /db_xref="GOA:P71019" /db_xref="InterPro:IPR004410" /db_xref="InterPro:IPR014043" /db_xref="InterPro:IPR016035" /db_xref="InterPro:IPR016036" /db_xref="InterPro:IPR020801" /db_xref="InterPro:IPR024925" /db_xref="SubtiList:BG11836" /db_xref="UniProtKB/Swiss-Prot:P71019" /translation="MSKIAFLFPGQGSQFIGMGKELYEQVPAAKRLFDEADETLETKL SSLIFEGDAEELTLTYNAQPALLTTSIAVLEKFKESGITPDFTAGHSLGEYSALVAAG ALSFKDAVYTVRKRGEFMNEAVPAGEGAMAAILGMDAEALKQVTDKVTEEGNLVQLAN LNCPGQIVISGTAKGVELASELAKENGAKRAIPLEVSGPFHSELMKPAAEKLKEVLDA CDIKDADVPVISNVSADVMTEKADIKEKLIEQLYSPVRFEESINKLIAEGVTTFIEIG PGKVLSGLVKKVNRRLKTIAVSDPETIELAIQTLKEENDNA*" gene 1663567..1664520 /gene="fabD" /locus_tag="BSU_15900" /old_locus_tag="BSU15900" CDS 1664513..1665253 /gene="fabG" /locus_tag="BSU_15910" /old_locus_tag="BSU15910" /EC_number="1.1.1.100" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:8759840, 12655455, 12682299, 19850612, 28126742" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8759840, 12655455, 12682299, 19850612, 28126742; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="beta-ketoacyl-acyl carrier protein reductase" /protein_id="NP_389473.1" /db_xref="EnsemblGenomes-Gn:BSU15910" /db_xref="EnsemblGenomes-Tr:CAB13464" /db_xref="GOA:P51831" /db_xref="InterPro:IPR002347" /db_xref="InterPro:IPR011284" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG11535" /db_xref="UniProtKB/Swiss-Prot:P51831" /translation="MLNDKTAIVTGASRGIGRSIALDLAKSGANVVVNYSGNEAKANE VVDEIKSMGRKAIAVKADVSNPEDVQNMIKETLSVFSTIDILVNNAGITRDNLIMRMK EDEWDDVININLKGVFNCTKAVTRQMMKQRSGRIINVSSIVGVSGNPGQANYVAAKAG VIGLTKSSAKELASRNITVNAIAPGFISTDMTDKLAKDVQDEMLKQIPLARFGEPSDV SSVVTFLASEGARYMTGQTLHIDGGMVM*" gene 1664513..1665253 /gene="fabG" /locus_tag="BSU_15910" /old_locus_tag="BSU15910" promotor_-35 1665284..1665288 /Source="Nicolas_upshift_promotors" /id="U1308" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.949050949050949" /psig=1 /xcortree=2635 /SigmaFactorBS="tgtaagttttttctcgaaaatttcatcgtagtttcTCTAGtt ttttaaaaacgaaTCCACTATAATACTTGAGGGgaggtgaattgctatggcagacaca t" /listShort="acpA, S577, rnc, smc, ftsY" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1665304..1665323 /Source="Nicolas_upshift_promotors" /id="U1308" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.949050949050949" /psig=1 /xcortree=2635 /SigmaFactorBS="tgtaagttttttctcgaaaatttcatcgtagtttcTCTAGtt ttttaaaaacgaaTCCACTATAATACTTGAGGGgaggtgaattgctatggcagacaca t" /listShort="acpA, S577, rnc, smc, ftsY" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1665309 /Source="Nicolas_upshifts" /id="U1308" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.949050949050949" /psig=1 /xcortree=2635 /SigmaFactorBS="tgtaagttttttctcgaaaatttcatcgtagtttcTCTAGtt ttttaaaaacgaaTCCACTATAATACTTGAGGGgaggtgaattgctatggcagacaca t" /listShort="acpA, S577, rnc, smc, ftsY" /GFF_Attribute="listLong" CDS 1665337..1665570 /gene="acpA" /locus_tag="BSU_15920" /old_locus_tag="BSU15920" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:8759840, 12682299, 19850612, 27467752" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8759840, 12682299, 19850612, 27467752; Product type c: carrier" /codon_start=1 /transl_table=11 /product="acyl carrier protein" /protein_id="NP_389474.1" /db_xref="EnsemblGenomes-Gn:BSU15920" /db_xref="EnsemblGenomes-Tr:CAB13465" /db_xref="GOA:P80643" /db_xref="InterPro:IPR003231" /db_xref="InterPro:IPR006162" /db_xref="InterPro:IPR009081" /db_xref="InterPro:IPR036736" /db_xref="PDB:1F80" /db_xref="PDB:1HY8" /db_xref="PDB:2X2B" /db_xref="SubtiList:BG11536" /db_xref="UniProtKB/Swiss-Prot:P80643" /translation="MADTLERVTKIIVDRLGVDEADVKLEASFKEDLGADSLDVVELV MELEDEFDMEISDEDAEKIATVGDAVNYIQNQQ*" gene 1665337..1665570 /gene="acpA" /locus_tag="BSU_15920" /old_locus_tag="BSU15920" downshifts 1665551 /Source="Nicolas_upshifts" /id="D883" /incds=0 /nref=22 /ntot=197 /MaxReadThrough="8.12206" /MaxDrop="4.1545" /score="-8.42930766" /energy="-17.4" /TU="U1306,U1307,U1308" /idTUdmin="U1306" /TUdmin="-880" /isTUend="FALSE" promotor_no_box 1665579..1665679 /Source="Nicolas_upshift_promotors" /id="U1309" /multdbtbs="-" /comp="M21" /sig="Sig-" /pcomp="0.502497502497502" /psig="0.030969030969031" /xcortree=1637 /SigmaFactorBS="taaaagtcccgccgaaacgcggggctttagccctttattcgt gcagttattacagcatgccgcttttacgcgcgctgtatccggtttagtcagagaagcg c" /listShort="S577, rnc, smc, ftsY" /GFF_Attribute="listLong" /label="promotor_no_box" S_feature 1665639..1665709 /Source="Nicolas_S_feature" /locus_tag="new_1665639_1665709" /HighExp="LBGstat, dia5, Cold, LBGtran, C30, Diami, G135, LBGexp, G/S, Oxctl" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="Sig-, SigA, SigA, SigA" /TUshortPSig="0.031, 1, 1, 0.999" /TUlongSig="SigA, SigA" /TUlongPSig="0.991, 0.991" /label="S577" upshifts 1665639 /Source="Nicolas_upshifts" /id="U1309" /multdbtbs="-" /comp="M21" /sig="Sig-" /pcomp="0.502497502497502" /psig="0.030969030969031" /xcortree=1637 /SigmaFactorBS="taaaagtcccgccgaaacgcggggctttagccctttattcgt gcagttattacagcatgccgcttttacgcgcgctgtatccggtttagtcagagaagcg c" /listShort="S577, rnc, smc, ftsY" /GFF_Attribute="listLong" CDS 1665710..1666459 /gene="rnc" /locus_tag="BSU_15930" /old_locus_tag="BSU15930" /EC_number="3.1.26.3" /experiment="publication(s) with functional evidences, PMID:11123676, 12682299, 16179796, 22412379, 23300471, 26883633" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11123676, 12682299, 16179796, 22412379, 23300471, 26883633; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="ribonuclease III" /protein_id="NP_389475.1" /db_xref="EnsemblGenomes-Gn:BSU15930" /db_xref="EnsemblGenomes-Tr:CAB13466" /db_xref="GOA:P51833" /db_xref="InterPro:IPR000999" /db_xref="InterPro:IPR011907" /db_xref="InterPro:IPR014720" /db_xref="InterPro:IPR036389" /db_xref="SubtiList:BG11537" /db_xref="UniProtKB/Swiss-Prot:P51833" /translation="MSKHSHYKDKKKFYKKVEQFKEFQERISVHFQNEKLLYQAFTHS SYVNEHRKKPYEDNERLEFLGDAVLELTISRFLFAKYPAMSEGDLTKLRAAIVCEPSL VSLAHELSFGDLVLLGKGEEMTGGRKRPALLADVFEAFIGALYLDQGLEPVESFLKVY VFPKINDGAFSHVMDFKSQLQEYVQRDGKGSLEYKISNEKGPAHNREFEAIVSLKGEP LGVGNGRSKKEAEQHAAQEALAKLQKHHTKQ*" gene 1665710..1666459 /gene="rnc" /locus_tag="BSU_15930" /old_locus_tag="BSU15930" downshifts 1666431 /Source="Nicolas_upshifts" /id="D884" /incds=0 /nref=78 /ntot=211 /MaxReadThrough="6.42554" /MaxDrop="5.70849" /score="-8.42930766" /energy="-17.4" /TU="U1307,U1308,U1309" /idTUdmin="U1306" /TUdmin=0 /isTUend="TRUE" promotor_-35 1666501..1666507 /Source="Nicolas_upshift_promotors" /id="U1310" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.816183816183816" /psig="0.985014985014985" /xcortree=110 /SigmaFactorBS="ggatttcagtatgtatgccgTCTTATTtgaccaatgttTATG ATAGAATTGAAATACTtattacataaggaggatcgctatgttcctcaaacgtttagac g" /listShort="smc, ftsY" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1666519..1666538 /Source="Nicolas_upshift_promotors" /id="U1310" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.816183816183816" /psig="0.985014985014985" /xcortree=110 /SigmaFactorBS="ggatttcagtatgtatgccgTCTTATTtgaccaatgttTATG ATAGAATTGAAATACTtattacataaggaggatcgctatgttcctcaaacgtttagac g" /listShort="smc, ftsY" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1666541 /Source="Nicolas_upshifts" /id="U1310" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.816183816183816" /psig="0.985014985014985" /xcortree=110 /SigmaFactorBS="ggatttcagtatgtatgccgTCTTATTtgaccaatgttTATG ATAGAATTGAAATACTtattacataaggaggatcgctatgttcctcaaacgtttagac g" /listShort="smc, ftsY" /GFF_Attribute="listLong" CDS 1666560..1670120 /gene="smc" /locus_tag="BSU_15940" /old_locus_tag="BSU15940" /function="16.9: Replicate" /experiment="publication(s) with functional evidences, PMID:9701812, 12100548, 12682299, 12897137, 15987505, 16272394, 26904953, 28154080" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9701812, 12100548, 12682299, 12897137, 15987505, 16272394, 26904953, 28154080; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="chromosome condensation and segregation SMC ATPase" /protein_id="NP_389476.2" /db_xref="EnsemblGenomes-Gn:BSU15940" /db_xref="EnsemblGenomes-Tr:CAB13467" /db_xref="GOA:P51834" /db_xref="InterPro:IPR003395" /db_xref="InterPro:IPR010935" /db_xref="InterPro:IPR011890" /db_xref="InterPro:IPR024704" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR036277" /db_xref="PDB:3ZGX" /db_xref="PDB:5H66" /db_xref="PDB:5H67" /db_xref="PDB:5NMO" /db_xref="PDB:5NNV" /db_xref="PDB:5XG3" /db_xref="SubtiList:BG11538" /db_xref="UniProtKB/Swiss-Prot:P51834" /translation="MFLKRLDVIGFKSFAERISVDFVKGVTAVVGPNGSGKSNITDAI RWVLGEQSARSLRGGKMEDIIFAGSDSRKRLNLAEVTLTLDNDDHFLPIDFHEVSVTR RVYRSGESEFLINNQPCRLKDIIDLFMDSGLGKEAFSIISQGKVEEILSSKAEDRRSI FEEAAGVLKYKTRKKKAENKLFETQDNLNRVEDILHELEGQVEPLKIQASIAKDYLEK KKELEHVEIALTAYDIEELHGKWSTLKEKVQMAKEEELAESSAISAKEAKIEDTRDKI QALDESVDELQQVLLVTSEELEKLEGRKEVLKERKKNAVQNQEQLEEAIVQFQQKETV LKEELSKQEAVFETLQAEVKQLRAQVKEKQQALSLHNENVEEKIEQLKSDYFELLNSQ ASIRNELQLLDDQMSQSAVTLQRLADNNEKHLQERHDISARKAACETEFARIEQEIHS QVGAYRDMQTKYEQKKRQYEKNESALYQAYQYVQQARSKKDMLETMQGDFSGFYQGVK EVLKAKERLGGIRGAVLELISTEQKYETAIEIALGASAQHVVTDDEQSARKAIQYLKQ NSFGRATFLPLSVIRDRQLQSRDAETAARHSSFLGVASELVTFDPAYRSVIQNLLGTV LITEDLKGANELAKLLGHRYRIVTLEGDVVNPGGSMTGGAVKKKNNSLLGRSRELEDV TKRLAEMEEKTALLEQEVKTLKHSIQDMEKKLADLRETGEGLRLKQQDVKGQLYELQV AEKNINTHLELYDQEKSALSESDEERKVRKRKLEEELSAVSEKMKQLEEDIDRLTKQK QTQSSTKESLSNELTELKIAAAKKEQACKGEEDNLARLKKELTETELALKEAKEDLSF LTSEMSSSTSGEEKLEEAAKHKLNDKTKTIELIALRRDQRIKLQHGLDTYERELKEMK RLYKQKTTLLKDEEVKLGRMEVELDNLLQYLREEYSLSFEGAKEKYQLETDPEEARKR VKLIKLAIEELGTVNLGSIDEFERVNERYKFLSEQKEDLTEAKNTLFQVIEEMDEEMT KRFNDTFVQIRSHFDQVFRSLFGGGRAELRLTDPNDLLHSGVEIIAQPPGKKLQNLNL LSGGERALTAIALLFSILKVRPVPFCVLDEVEAALDEANVFRFAQYLKKYSSDTQFIV ITHRKGTMEEADVLYGVTMQESGVSKVISVKLEETKEFVQ*" gene 1666560..1670120 /gene="smc" /locus_tag="BSU_15940" /old_locus_tag="BSU15940" S_feature complement(1670054..1671124) /Source="Nicolas_S_feature" /locus_tag="new_1670054_1671124_c" /HighExp="Cold, C30, Gly, T0.30H, Pyr, T-4.40H, G135, Lbstat, Fru, T-5.40H" /AntisenseName="ftsY" /AntisenseCor="-3.7172405649441298E-3" /AntisenseRegPval=0 /CDS_PredictionProba="NA" /TUshortSig="SigD" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S578" CDS 1670140..1671129 /gene="ftsY" /locus_tag="BSU_15950" /old_locus_tag="BSU15950" /function="16.1: Circulate" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:11021934, 11123669, 11166993, 12682299, 15995216, 16705751, 22056770" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11021934, 11123669, 11166993, 12682299, 15995216, 16705751, 22056770; Product type rc: receptor" /codon_start=1 /transl_table=11 /product="signal recognition particle (docking protein)" /protein_id="NP_389477.1" /db_xref="EnsemblGenomes-Gn:BSU15950" /db_xref="EnsemblGenomes-Tr:CAB13468" /db_xref="GOA:P51835" /db_xref="InterPro:IPR000897" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR004390" /db_xref="InterPro:IPR013822" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR036225" /db_xref="SubtiList:BG11539" /db_xref="UniProtKB/Swiss-Prot:P51835" /translation="MSFFKKLKEKITKQTDSVSEKFKDGLEKTRNSFQNKVNDLVSRY RKVDEDFFEELEEVLISADVGFTTVMELIDELKKEVKRRNIQDPKEVQSVISEKLVEI YNSGDEQISELNIQDGRLNVILLVGVNGVGKTTTIGKLAHKMKQEGKSVVLAAGDTFR AGAIEQLEVWGERTGVPVIKQTAGSDPAAVIYDAVHAAKARNADVLICDTAGRLQNKV NLMKELEKVKRVIEREVPEAPHEVLLALDATTGQNAMAQAKEFSKATNVTGIALTKLD GTAKGGIVLAIRNELHIPVKLVGLGEKVDDLQEFDPESYVYGLFSDLVEKADD*" gene 1670140..1671129 /gene="ftsY" /locus_tag="BSU_15950" /old_locus_tag="BSU15950" downshifts 1671116 /Source="Nicolas_upshifts" /id="D885" /incds=0 /nref=220 /ntot=261 /MaxReadThrough="2.98458" /MaxDrop="6.84303" /score="49.5808683" /energy="-14.4" /TU="NA" /idTUdmin="U1307" /TUdmin="-1" /isTUend="TRUE" CDS complement(1671166..1671651) /gene="ylqB" /locus_tag="BSU_15960" /old_locus_tag="BSU15960" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 15033535, 22287527" /codon_start=1 /transl_table=11 /product="conserved exported protein of unknown function" /protein_id="NP_389478.1" /db_xref="EnsemblGenomes-Gn:BSU15960" /db_xref="EnsemblGenomes-Tr:CAB13469" /db_xref="GOA:O31737" /db_xref="InterPro:IPR008969" /db_xref="InterPro:IPR008979" /db_xref="SubtiList:BG13401" /db_xref="UniProtKB/Swiss-Prot:O31737" /translation="MKKIGLLFMLCLAALFTIGFPAQQADAAEAPYKASITNISTDGG VYGKINYGQGQYWRVKYNITVSGKLLDQNGQPVPNAPVRFEADTKVGNTTQTASGTTD ANGTFEVPMYLGPAAGYYTYYTSVSVHYYDIIPFRVFSGESRLVSTDNSLYHFAYQVR R*" gene complement(1671166..1671651) /gene="ylqB" /locus_tag="BSU_15960" /old_locus_tag="BSU15960" downshifts complement(1671169) /Source="Nicolas_upshifts" /id="D886" /incds=0 /nref=139 /ntot=244 /MaxReadThrough="6.77251" /MaxDrop="6.10895" /score="32.8428224" /energy="-14.4" /TU="U1311" /idTUdmin="U1311" /TUdmin="-1076" /isTUend="FALSE" promotor_-10 complement(1671673..1671691) /Source="Nicolas_upshift_promotors" /id="U1311" /multdbtbs="SigD" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2831 /SigmaFactorBS="tatcttgtcaaagcggcgattaacttttccaaaatacGCTAA ATAtcatccaatttatTCCGATATTGTATATGAACcctattttaaggaggatttttat g" /listShort="ylqB, S578" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1671689) /Source="Nicolas_upshifts" /id="U1311" /multdbtbs="SigD" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2831 /SigmaFactorBS="tatcttgtcaaagcggcgattaacttttccaaaatacGCTAA ATAtcatccaatttatTCCGATATTGTATATGAACcctattttaaggaggatttttat g" /listShort="ylqB, S578" /GFF_Attribute="listLong" promotor_-35 complement(1671705..1671712) /Source="Nicolas_upshift_promotors" /id="U1311" /multdbtbs="SigD" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2831 /SigmaFactorBS="tatcttgtcaaagcggcgattaacttttccaaaatacGCTAA ATAtcatccaatttatTCCGATATTGTATATGAACcctattttaaggaggatttttat g" /listShort="ylqB, S578" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1671754..1671760 /Source="Nicolas_upshift_promotors" /id="U1312" /multdbtbs="SigA" /comp="M17" /sig="SigA" /pcomp="0.709290709290709" /psig=1 /xcortree=2649 /SigmaFactorBS="tttggaaaagttaatcgccgctttgacaagataaaaaCTTGA CAgtgtcattaaaaccGTGTAAACTAAGTTATCGTAaagggatttgacttaacaaagg g" /listShort="ylxM, ffh, S579, rpsP, ylqC, S580, ylqD, rimM, trmD" /listLong="NA, rplS, S581, rbgA, rnhB, ylqG, ylqH, S582, sucC, sucD, dprA, S583, topA, trmFO, codV, clpQ, clpY, codY, S584, flgB, flgC, fliE, fliF, fliG, S585, fliH, fliI, fliJ, ylxF, fliK, flgD, flgE, ylzI, fliL, fliM, fliY, cheY, fliZ, fliP, fliQ, fliR, flhB, flhA, flhF, ylxH, cheB, cheA, cheW, cheC, cheD, sigD, ylxL, S586, rpsB, S587, tsf, S588, pyrH, frr, S589, uppS, cdsA, dxr, rseP, proS, S590, polC, S591, S592, S593, ylxS, nusA, ylxR, rplGA, infB, ylxP, rbfA, truB, ribC, S594, rpsO, S595, pnpA, S596, ylxY, mlpA" /label="promotor_-35" promotor_-10 1671775..1671794 /Source="Nicolas_upshift_promotors" /id="U1312" /multdbtbs="SigA" /comp="M17" /sig="SigA" /pcomp="0.709290709290709" /psig=1 /xcortree=2649 /SigmaFactorBS="tttggaaaagttaatcgccgctttgacaagataaaaaCTTGA CAgtgtcattaaaaccGTGTAAACTAAGTTATCGTAaagggatttgacttaacaaagg g" /listShort="ylxM, ffh, S579, rpsP, ylqC, S580, ylqD, rimM, trmD" /listLong="NA, rplS, S581, rbgA, rnhB, ylqG, ylqH, S582, sucC, sucD, dprA, S583, topA, trmFO, codV, clpQ, clpY, codY, S584, flgB, flgC, fliE, fliF, fliG, S585, fliH, fliI, fliJ, ylxF, fliK, flgD, flgE, ylzI, fliL, fliM, fliY, cheY, fliZ, fliP, fliQ, fliR, flhB, flhA, flhF, ylxH, cheB, cheA, cheW, cheC, cheD, sigD, ylxL, S586, rpsB, S587, tsf, S588, pyrH, frr, S589, uppS, cdsA, dxr, rseP, proS, S590, polC, S591, S592, S593, ylxS, nusA, ylxR, rplGA, infB, ylxP, rbfA, truB, ribC, S594, rpsO, S595, pnpA, S596, ylxY, mlpA" /label="promotor_-10" upshifts 1671777 /Source="Nicolas_upshifts" /id="U1312" /multdbtbs="SigA" /comp="M17" /sig="SigA" /pcomp="0.709290709290709" /psig=1 /xcortree=2649 /SigmaFactorBS="tttggaaaagttaatcgccgctttgacaagataaaaaCTTGA CAgtgtcattaaaaccGTGTAAACTAAGTTATCGTAaagggatttgacttaacaaagg g" /listShort="ylxM, ffh, S579, rpsP, ylqC, S580, ylqD, rimM, trmD" /listLong="NA, rplS, S581, rbgA, rnhB, ylqG, ylqH, S582, sucC, sucD, dprA, S583, topA, trmFO, codV, clpQ, clpY, codY, S584, flgB, flgC, fliE, fliF, fliG, S585, fliH, fliI, fliJ, ylxF, fliK, flgD, flgE, ylzI, fliL, fliM, fliY, cheY, fliZ, fliP, fliQ, fliR, flhB, flhA, flhF, ylxH, cheB, cheA, cheW, cheC, cheD, sigD, ylxL, S586, rpsB, S587, tsf, S588, pyrH, frr, S589, uppS, cdsA, dxr, rseP, proS, S590, polC, S591, S592, S593, ylxS, nusA, ylxR, rplGA, infB, ylxP, rbfA, truB, ribC, S594, rpsO, S595, pnpA, S596, ylxY, mlpA" CDS 1671828..1672160 /gene="ylxM" /locus_tag="BSU_15970" /old_locus_tag="BSU15970" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 11274114, 24659773; Product type f: factor" /codon_start=1 /transl_table=11 /product="component of the signal recognition particle (SRP) protein-targeting pathway" /protein_id="NP_389479.1" /db_xref="EnsemblGenomes-Gn:BSU15970" /db_xref="EnsemblGenomes-Tr:CAB13470" /db_xref="GOA:P37104" /db_xref="InterPro:IPR007394" /db_xref="InterPro:IPR013324" /db_xref="InterPro:IPR036388" /db_xref="SubtiList:BG10829" /db_xref="UniProtKB/Swiss-Prot:P37104" /translation="MSLEKTTRMNYLFDFYQSLLTSKQKSYMSLYYLDDFSLGEIAEE YEVSRQAVYDNIKRTEAMLEQYEEKLLLLKKFQERKEMFNKLKELASGSKEEEEITAL IEALEKLD*" gene 1671828..1672160 /gene="ylxM" /locus_tag="BSU_15970" /old_locus_tag="BSU15970" downshifts complement(1671831) /Source="Nicolas_upshifts" /id="D887" /incds=0 /nref=3 /ntot=52 /MaxReadThrough="1.40385" /MaxDrop="4.6092" /score="32.8428224" /energy="-14.4" /TU="NA" /idTUdmin="U1311" /TUdmin="-1738" /isTUend="FALSE" CDS 1672174..1673514 /gene="ffh" /locus_tag="BSU_15980" /old_locus_tag="BSU15980" /function="16.13: Shape" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:7511896, 8662730, 10222262, 10224127, 10658653, 12682299, 11123669, 22056770, 26344568" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7511896, 8662730, 10222262, 10224127, 10658653, 12682299, 11123669, 22056770, 26344568; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="signal recognition particle-like (SRP) GTPase" /protein_id="NP_389480.1" /db_xref="EnsemblGenomes-Gn:BSU15980" /db_xref="EnsemblGenomes-Tr:CAB13471" /db_xref="GOA:P37105" /db_xref="InterPro:IPR000897" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR004125" /db_xref="InterPro:IPR004780" /db_xref="InterPro:IPR013822" /db_xref="InterPro:IPR022941" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR036891" /db_xref="PDB:4UE4" /db_xref="SubtiList:BG10830" /db_xref="UniProtKB/Swiss-Prot:P37105" /translation="MAFEGLADRLQQTISKIRGKGKVSEQDVKEMMREVRLALLEADV NFKVVKDFVKKVSERAVGQDVMKSLTPGQQVIKVVQEELTELMGGEESKIAVAKRPPT VIMMVGLQGAGKTTTSGKLANLLRKKHNRKPMLVAADIYRPAAIKQLETLGKQLDMPV FSLGDQVSPVEIAKQAIEKAKEEHYDYVILDTAGRLHIDHELMDELTNVKEIANPEEI FLVVDSMTGQDAVNVAKSFNEQLGLTGVVLTKLDGDTRGGAALSIRAVTNTPIKFAGL GEKLDALEPFHPERMASRILGMGDVLTLIEKAQASVDEDKAKELEQKMRTMSFTLDDF LEQLGQVRNMGPLDELLQMMPGAGKMKGLKNIQVDEKQLNHVEAIIKSMTVLEKEQPD IINASRRKRIAKGSGTSVQEVNRLLKQFDEMKKMMKQMTNMSKGKKKGFKLPFM*" gene 1672174..1673514 /gene="ffh" /locus_tag="BSU_15980" /old_locus_tag="BSU15980" S_feature 1673515..1673619 /Source="Nicolas_S_feature" /locus_tag="new_1673515_1673619" /HighExp="Cold, G135, C30, G180, LPhT, HPh, Paraq, LPh, Oxctl, G150" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S579" CDS 1673620..1673892 /gene="rpsP" /locus_tag="BSU_15990" /old_locus_tag="BSU15990" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:6419023, 12682299, 20034956" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 6419023, 12682299, 20034956; Product type s: structure" /codon_start=1 /transl_table=11 /product="ribosomal protein S16 (BS17)" /protein_id="NP_389481.1" /db_xref="EnsemblGenomes-Gn:BSU15990" /db_xref="EnsemblGenomes-Tr:CAB13472" /db_xref="GOA:P21474" /db_xref="InterPro:IPR000307" /db_xref="InterPro:IPR020592" /db_xref="InterPro:IPR023803" /db_xref="PDB:3J9W" /db_xref="PDB:5NJT" /db_xref="SubtiList:BG10831" /db_xref="UniProtKB/Swiss-Prot:P21474" /translation="MAVKIRLKRMGAKKSPFYRIVVADSRSPRDGRFIETVGTYNPVA KPAEVKIDEELALKWLQTGAKPSDTVRNLFSSQGIMEKFHNAKQGK*" gene 1673620..1673892 /gene="rpsP" /locus_tag="BSU_15990" /old_locus_tag="BSU15990" CDS 1673892..1674137 /gene="ylqC" /locus_tag="BSU_16000" /old_locus_tag="BSU16000" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 22333191, 22720735, 26483775; Product type f: factor" /codon_start=1 /transl_table=11 /product="putative RNA binding protein" /protein_id="NP_389482.1" /db_xref="EnsemblGenomes-Gn:BSU16000" /db_xref="EnsemblGenomes-Tr:CAB13473" /db_xref="GOA:O31738" /db_xref="InterPro:IPR009019" /db_xref="InterPro:IPR015946" /db_xref="InterPro:IPR020627" /db_xref="SubtiList:BG13402" /db_xref="UniProtKB/Swiss-Prot:O31738" /translation="MTDQHLEDLIVHIVTPLVDHPDDIRVIREETDQKIALRLSVHKS DTGKVIGKQGRTAKAIRTAVFAAGVQSSKKVQFEIFD*" gene 1673892..1674137 /gene="ylqC" /locus_tag="BSU_16000" /old_locus_tag="BSU16000" downshifts 1674109 /Source="Nicolas_upshifts" /id="D888" /incds=0 /nref=41 /ntot=178 /MaxReadThrough="6.57974" /MaxDrop="4.803" /score="-7.01631592" /energy="-5.6" /TU="U1312" /idTUdmin="U1312" /TUdmin="-1804" /isTUend="FALSE" S_feature 1674154..1674258 /Source="Nicolas_S_feature" /locus_tag="new_1674154_1674258" /HighExp="G180, Oxctl, G150, G135, Paraq, LBGexp, H2O2, HPh, LPh, dia0" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S580" CDS 1674259..1674645 /gene="ylqD" /locus_tag="BSU_16010" /old_locus_tag="BSU16010" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 22720735" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_389483.1" /db_xref="EnsemblGenomes-Gn:BSU16010" /db_xref="EnsemblGenomes-Tr:CAB13474" /db_xref="InterPro:IPR021297" /db_xref="SubtiList:BG13403" /db_xref="UniProtKB/Swiss-Prot:O31739" /translation="MQIIHRVAVMQVLTERSKEKLLASFAEKKQMLERECSQLYFQLR KHEKEQQNPNMIEQFKKAIEKRKDDIKIIDFQIAQVHTLPLGSELKEKEVDALLTIEA GDDWHEKTAANTIVIKDGKVIEIRQR*" gene 1674259..1674645 /gene="ylqD" /locus_tag="BSU_16010" /old_locus_tag="BSU16010" CDS 1674650..1675174 /gene="rimM" /locus_tag="BSU_16020" /old_locus_tag="BSU16020" /function="16.8: Protect" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 15496525, 16014871, 27382067; Product type f: factor" /codon_start=1 /transl_table=11 /product="16S rRNA processing protein" /protein_id="NP_389484.1" /db_xref="EnsemblGenomes-Gn:BSU16020" /db_xref="EnsemblGenomes-Tr:CAB13475" /db_xref="GOA:O31740" /db_xref="InterPro:IPR002676" /db_xref="InterPro:IPR009000" /db_xref="InterPro:IPR011033" /db_xref="InterPro:IPR011961" /db_xref="InterPro:IPR027275" /db_xref="InterPro:IPR036976" /db_xref="SubtiList:BG13404" /db_xref="UniProtKB/Swiss-Prot:O31740" /translation="MTKRWFNVGKIVNTHGIKGEVRVISKTDFAEERYKPGNTLYLFM DGRNEPVEVTVNTHRLHKQFHLLQFKERQNLNEVEELKNAIIKVPEEELGELNEGEFY FHEIIGCEVFTEEGELIGKVKEILTPGANDVWVIGRKGKKDALIPYIESVVKHIDVRE KKIEIELMEGLIDE*" gene 1674650..1675174 /gene="rimM" /locus_tag="BSU_16020" /old_locus_tag="BSU16020" CDS 1675171..1675902 /gene="trmD" /locus_tag="BSU_16030" /old_locus_tag="BSU16030" /EC_number="2.1.1.228" /function="16.2: Construct biomass (Anabolism)" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 10094308, 11532950, 12682299, 12773376, 15060037, 27881678, 28601227; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="tRNA(m1G37)methyltransferase" /protein_id="NP_389485.1" /db_xref="EnsemblGenomes-Gn:BSU16030" /db_xref="EnsemblGenomes-Tr:CAB13476" /db_xref="GOA:O31741" /db_xref="InterPro:IPR002649" /db_xref="InterPro:IPR016009" /db_xref="InterPro:IPR029026" /db_xref="InterPro:IPR029028" /db_xref="SubtiList:BG12687" /db_xref="UniProtKB/Swiss-Prot:O31741" /translation="MKIDFLTLFPEMFEGVLGSSILQKAQEKDAVQFQVVNFREYSDN KHNTVDDYPYGGGAGMVLKPQPVFDAVEDLTSKAAAAPRIILVCPQGERFTQKKAEQL AKEEHLLFICGHYEGYDERIREHLVTDEISIGDFVLTGGELPAMMIADSVVRLLPGVL GKEASHIEDSFSTGLLEHPHYTRPADYKGLKVPETLLSGNHAKIEEWRNKESIRRTYL RRPDLLKDHPLTEQQRKWISEWEKE*" gene 1675171..1675902 /gene="trmD" /locus_tag="BSU_16030" /old_locus_tag="BSU16030" promotor_-35 1675908..1675915 /Source="Nicolas_upshift_promotors" /id="U1313" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.822177822177822" /psig=1 /xcortree=2646 /SigmaFactorBS="aagtggatttctgaatgggaaaaagaatagattttATTGCAT AggctatgaaattgTGATAAGATACTACTTGTGGcttaagcgggcttatccgctgcaa g" /listShort="NA, rplS, S581, rbgA, rnhB, ylqG, ylqH, S582" /listLong="sucC, sucD, dprA, S583, topA, trmFO, codV, clpQ, clpY, codY, S584, flgB, flgC, fliE, fliF, fliG, S585, fliH, fliI, fliJ, ylxF, fliK, flgD, flgE, ylzI, fliL, fliM, fliY, cheY, fliZ, fliP, fliQ, fliR, flhB, flhA, flhF, ylxH, cheB, cheA, cheW, cheC, cheD, sigD, ylxL, S586, rpsB, S587, tsf, S588, pyrH, frr, S589, uppS, cdsA, dxr, rseP, proS, S590, polC, S591, S592, S593, ylxS, nusA, ylxR, rplGA, infB, ylxP, rbfA, truB, ribC, S594, rpsO, S595, pnpA, S596, ylxY, mlpA" /label="promotor_-35" promotor_-10 1675929..1675948 /Source="Nicolas_upshift_promotors" /id="U1313" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.822177822177822" /psig=1 /xcortree=2646 /SigmaFactorBS="aagtggatttctgaatgggaaaaagaatagattttATTGCAT AggctatgaaattgTGATAAGATACTACTTGTGGcttaagcgggcttatccgctgcaa g" /listShort="NA, rplS, S581, rbgA, rnhB, ylqG, ylqH, S582" /listLong="sucC, sucD, dprA, S583, topA, trmFO, codV, clpQ, clpY, codY, S584, flgB, flgC, fliE, fliF, fliG, S585, fliH, fliI, fliJ, ylxF, fliK, flgD, flgE, ylzI, fliL, fliM, fliY, cheY, fliZ, fliP, fliQ, fliR, flhB, flhA, flhF, ylxH, cheB, cheA, cheW, cheC, cheD, sigD, ylxL, S586, rpsB, S587, tsf, S588, pyrH, frr, S589, uppS, cdsA, dxr, rseP, proS, S590, polC, S591, S592, S593, ylxS, nusA, ylxR, rplGA, infB, ylxP, rbfA, truB, ribC, S594, rpsO, S595, pnpA, S596, ylxY, mlpA" /label="promotor_-10" upshifts 1675933 /Source="Nicolas_upshifts" /id="U1313" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.822177822177822" /psig=1 /xcortree=2646 /SigmaFactorBS="aagtggatttctgaatgggaaaaagaatagattttATTGCAT AggctatgaaattgTGATAAGATACTACTTGTGGcttaagcgggcttatccgctgcaa g" /listShort="NA, rplS, S581, rbgA, rnhB, ylqG, ylqH, S582" /listLong="sucC, sucD, dprA, S583, topA, trmFO, codV, clpQ, clpY, codY, S584, flgB, flgC, fliE, fliF, fliG, S585, fliH, fliI, fliJ, ylxF, fliK, flgD, flgE, ylzI, fliL, fliM, fliY, cheY, fliZ, fliP, fliQ, fliR, flhB, flhA, flhF, ylxH, cheB, cheA, cheW, cheC, cheD, sigD, ylxL, S586, rpsB, S587, tsf, S588, pyrH, frr, S589, uppS, cdsA, dxr, rseP, proS, S590, polC, S591, S592, S593, ylxS, nusA, ylxR, rplGA, infB, ylxP, rbfA, truB, ribC, S594, rpsO, S595, pnpA, S596, ylxY, mlpA" misc_RNA 1675981..1676022 /locus_tag="BSU_misc_RNA_30" /product="L19_leader" gene 1675981..1676022 /locus_tag="BSU_misc_RNA_30" CDS 1676042..1676389 /gene="rplS" /locus_tag="BSU_16040" /old_locus_tag="BSU16040" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 12682299, 16272117, 27477481; Product type f: factor" /codon_start=1 /transl_table=11 /product="ribosomal protein L19" /protein_id="NP_389486.2" /db_xref="EnsemblGenomes-Gn:BSU16040" /db_xref="EnsemblGenomes-Tr:CAB13477" /db_xref="GOA:O31742" /db_xref="InterPro:IPR001857" /db_xref="InterPro:IPR008991" /db_xref="InterPro:IPR018257" /db_xref="PDB:3J3V" /db_xref="PDB:3J3W" /db_xref="PDB:3J9W" /db_xref="PDB:5NJT" /db_xref="SubtiList:BG12667" /db_xref="UniProtKB/Swiss-Prot:O31742" /translation="MQKLIEDITKEQLRTDLPAFRPGDTLRVHVKVVEGNRERIQIFE GVVIKRRGGGISETFTVRKISYGVGVERTFPVHTPKIAKIEVVRYGKVRRAKLYYLRE LRGKAARIKEIRR*" gene 1676042..1676389 /gene="rplS" /locus_tag="BSU_16040" /old_locus_tag="BSU16040" downshifts 1676391 /Source="Nicolas_upshifts" /id="D889" /incds=0 /nref=212 /ntot=274 /MaxReadThrough="6.00308" /MaxDrop="9.06015" /score="23.9942041" /energy="-12.6" /TU="U1313" /idTUdmin="U1312" /TUdmin=478 /isTUend="FALSE" promotor_-35 1676444..1676450 /Source="Nicolas_upshift_promotors" /id="U1314" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.496503496503497" /psig="0.995004995004995" /xcortree=2756 /SigmaFactorBS="aaagagcttgttacctgtaacaagctctttttttatacagaA TTTGAAaatgccggacaggCATCGTAAAATACATAAAGGacaacaatgaatcatgcat a" /listShort="S581, rbgA" /GFF_Attribute="listLong" /label="promotor_-35" S_feature 1676463..1676531 /Source="Nicolas_S_feature" /locus_tag="new_1676463_1676531" /HighExp="Oxctl, G180, Paraq, G135, H2O2, LBGstat, dia15, G150, HPh, Cold" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.149563" /TUshortSig="SigA, SigA" /TUshortPSig="0.995, 1" /TUlongSig="SigA" /TUlongPSig=1 /label="S581" upshifts 1676463 /Source="Nicolas_upshifts" /id="U1314" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.496503496503497" /psig="0.995004995004995" /xcortree=2756 /SigmaFactorBS="aaagagcttgttacctgtaacaagctctttttttatacagaA TTTGAAaatgccggacaggCATCGTAAAATACATAAAGGacaacaatgaatcatgcat a" /listShort="S581, rbgA" /GFF_Attribute="listLong" promotor_-10 1676464..1676483 /Source="Nicolas_upshift_promotors" /id="U1314" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.496503496503497" /psig="0.995004995004995" /xcortree=2756 /SigmaFactorBS="aaagagcttgttacctgtaacaagctctttttttatacagaA TTTGAAaatgccggacaggCATCGTAAAATACATAAAGGacaacaatgaatcatgcat a" /listShort="S581, rbgA" /GFF_Attribute="listLong" /label="promotor_-10" CDS 1676532..1677380 /gene="rbgA" /locus_tag="BSU_16050" /old_locus_tag="BSU16050" /function="16.6: Maintain" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:12682299, 16390447, 16431913, 16997968, 17613524, 22267738, 25330043, 26951678" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12682299, 16390447, 16431913, 16997968, 17613524, 22267738, 25330043, 26951678; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="ribosome biogenesis GTPase A" /protein_id="NP_389487.1" /db_xref="EnsemblGenomes-Gn:BSU16050" /db_xref="EnsemblGenomes-Tr:CAB13478" /db_xref="GOA:O31743" /db_xref="InterPro:IPR006073" /db_xref="InterPro:IPR016478" /db_xref="InterPro:IPR019991" /db_xref="InterPro:IPR023179" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR030378" /db_xref="PDB:1PUJ" /db_xref="SubtiList:BG13405" /db_xref="UniProtKB/Swiss-Prot:O31743" /translation="MTIQWFPGHMAKARREVTEKLKLIDIVYELVDARIPMSSRNPMI EDILKNKPRIMLLNKADKADAAVTQQWKEHFENQGIRSLSINSVNGQGLNQIVPASKE ILQEKFDRMRAKGVKPRAIRALIIGIPNVGKSTLINRLAKKNIAKTGDRPGITTSQQW VKVGKELELLDTPGILWPKFEDELVGLRLAVTGAIKDSIINLQDVAVFGLRFLEEHYP ERLKERYGLDEIPEDIAELFDAIGEKRGCLMSGGLINYDKTTEVIIRDIRTEKFGRLS FEQPTM*" gene 1676532..1677380 /gene="rbgA" /locus_tag="BSU_16050" /old_locus_tag="BSU16050" promotor_-35 1677401..1677408 /Source="Nicolas_upshift_promotors" /id="U1315" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2823 /SigmaFactorBS="gacgatgtaaaggcgcgcagaaatgcgggtCTTTATTTtttc ttggctgaACCGATACATACAGTAAGGgagaagagaaagtgaatacattaaccgtaaa g" /listShort="rnhB, ylqG, ylqH, S582" /listLong="sucC, sucD, dprA, S583, topA, trmFO, codV, clpQ, clpY, codY, S584, flgB, flgC, fliE, fliF, fliG, S585, fliH, fliI, fliJ, ylxF, fliK, flgD, flgE, ylzI, fliL, fliM, fliY, cheY, fliZ, fliP, fliQ, fliR, flhB, flhA, flhF, ylxH, cheB, cheA, cheW, cheC, cheD, sigD, ylxL, S586, rpsB, S587, tsf, S588, pyrH, frr, S589, uppS, cdsA, dxr, rseP, proS, S590, polC, S591, S592, S593, ylxS, nusA, ylxR, rplGA, infB, ylxP, rbfA, truB, ribC, S594, rpsO, S595, pnpA, S596, ylxY, mlpA" /label="promotor_-35" promotor_-10 1677421..1677439 /Source="Nicolas_upshift_promotors" /id="U1315" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2823 /SigmaFactorBS="gacgatgtaaaggcgcgcagaaatgcgggtCTTTATTTtttc ttggctgaACCGATACATACAGTAAGGgagaagagaaagtgaatacattaaccgtaaa g" /listShort="rnhB, ylqG, ylqH, S582" /listLong="sucC, sucD, dprA, S583, topA, trmFO, codV, clpQ, clpY, codY, S584, flgB, flgC, fliE, fliF, fliG, S585, fliH, fliI, fliJ, ylxF, fliK, flgD, flgE, ylzI, fliL, fliM, fliY, cheY, fliZ, fliP, fliQ, fliR, flhB, flhA, flhF, ylxH, cheB, cheA, cheW, cheC, cheD, sigD, ylxL, S586, rpsB, S587, tsf, S588, pyrH, frr, S589, uppS, cdsA, dxr, rseP, proS, S590, polC, S591, S592, S593, ylxS, nusA, ylxR, rplGA, infB, ylxP, rbfA, truB, ribC, S594, rpsO, S595, pnpA, S596, ylxY, mlpA" /label="promotor_-10" upshifts 1677431 /Source="Nicolas_upshifts" /id="U1315" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2823 /SigmaFactorBS="gacgatgtaaaggcgcgcagaaatgcgggtCTTTATTTtttc ttggctgaACCGATACATACAGTAAGGgagaagagaaagtgaatacattaaccgtaaa g" /listShort="rnhB, ylqG, ylqH, S582" /listLong="sucC, sucD, dprA, S583, topA, trmFO, codV, clpQ, clpY, codY, S584, flgB, flgC, fliE, fliF, fliG, S585, fliH, fliI, fliJ, ylxF, fliK, flgD, flgE, ylzI, fliL, fliM, fliY, cheY, fliZ, fliP, fliQ, fliR, flhB, flhA, flhF, ylxH, cheB, cheA, cheW, cheC, cheD, sigD, ylxL, S586, rpsB, S587, tsf, S588, pyrH, frr, S589, uppS, cdsA, dxr, rseP, proS, S590, polC, S591, S592, S593, ylxS, nusA, ylxR, rplGA, infB, ylxP, rbfA, truB, ribC, S594, rpsO, S595, pnpA, S596, ylxY, mlpA" CDS 1677451..1678218 /gene="rnhB" /locus_tag="BSU_16060" /old_locus_tag="BSU16060" /EC_number="3.1.26.4" /function="16.2: Construct biomass (Anabolism)" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:10094689, 12475934, 23882084, 23937561, 29078353" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10094689, 12475934, 23882084, 23937561, 29078353; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="ribonuclease HII" /protein_id="NP_389488.1" /db_xref="EnsemblGenomes-Gn:BSU16060" /db_xref="EnsemblGenomes-Tr:CAB13479" /db_xref="GOA:O31744" /db_xref="InterPro:IPR001352" /db_xref="InterPro:IPR012337" /db_xref="InterPro:IPR022898" /db_xref="InterPro:IPR024567" /db_xref="InterPro:IPR036397" /db_xref="SubtiList:BG12666" /db_xref="UniProtKB/Swiss-Prot:O31744" /translation="MNTLTVKDIKDRLQEVKDAQDPFIAQCENDPRKSVQTLVEQWLK KQAKEKALKEQWVNMTSYERLARNKGFRLIAGVDEVGRGPLAGPVVASAVILPEECEI LGLTDSKKLSEKKREEYYELIMKEALAVGIGIVEATVIDEINIYEASKMAMVKAIQDL SDTPDYLLVDAMTLPLDTAQASIIKGDAKSVSIAAGACIAKVTRDRMMSAYAETYPMY GFEKNKGYGTKEHLEALAAYGPTELHRKTFAPVQSFR*" gene 1677451..1678218 /gene="rnhB" /locus_tag="BSU_16060" /old_locus_tag="BSU16060" CDS 1678250..1679980 /gene="ylqG" /locus_tag="BSU_16070" /old_locus_tag="BSU16070" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative glycosyltransferase" /protein_id="NP_389489.1" /db_xref="EnsemblGenomes-Gn:BSU16070" /db_xref="EnsemblGenomes-Tr:CAB13480" /db_xref="SubtiList:BG13406" /db_xref="UniProtKB/Swiss-Prot:O31745" /translation="MNIRNDVQKALQHLFGRTAVPQETSKVNEALNGEKRLLLGKVLR LLGDQHALIQVGNQTVQGKLETQLRPQAYYWFSYEKKTAEQTGRLQVVQSFDQNPKTI QDAAGKLLNAISVKTSNAALMMTGAMLKSKTPVTENDIKTAVRWMDTLPSQDTKKAVE TVLFALKRDLPIHSEILNGVHAVKSPVPLHQHVSQLLQAIDQNPQQSQMMSKLKEAVT VLLNSEIDVHAERLIDKLISLTDNTKAPSPTNTAGSRELSTPAGSPGKASLPIANHTA EQGSIQEEPVKTAADIPIKEARQLLVKLTESAEKNSLQIVKEAANWIKAAASSGDSKS LAASAVLQAAQVTDQEAEVFLKAVQQTAPHLADKADVLSFLSKVKTAIGARDEVAFIK AFEQGSAVTSGEMQSIKLALSALRASHEVAEPVKQEADQLFHKLNGQLFMQQDHPSYS QIVMSFPMFSKSGVQDMTVLFKGKKEADGKLDPSHCRLLFLLQLDTLKETVVDCLVQQ KVMTITIETDFELQAAIDPMVPALKQGLKEMGYSLSGVNAKKRVHTEEKASIDQYITS ISDQEVDVKI*" gene 1678250..1679980 /gene="ylqG" /locus_tag="BSU_16070" /old_locus_tag="BSU16070" upshifts complement(1679487) /Source="Nicolas_upshifts" /id="U1316" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.78921078921079" /psig="0.827172827172827" /xcortree=1797 /SigmaFactorBS="aaaagctgatcggcttctTGTTTGACtggttcggctacctCA TGCGATGCTCTTAAGGCAgaaagagccagcttgatggattgcatttcgccagatgtga c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 complement(1679488..1679507) /Source="Nicolas_upshift_promotors" /id="U1316" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.78921078921079" /psig="0.827172827172827" /xcortree=1797 /SigmaFactorBS="aaaagctgatcggcttctTGTTTGACtggttcggctacctCA TGCGATGCTCTTAAGGCAgaaagagccagcttgatggattgcatttcgccagatgtga c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 complement(1679522..1679529) /Source="Nicolas_upshift_promotors" /id="U1316" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.78921078921079" /psig="0.827172827172827" /xcortree=1797 /SigmaFactorBS="aaaagctgatcggcttctTGTTTGACtggttcggctacctCA TGCGATGCTCTTAAGGCAgaaagagccagcttgatggattgcatttcgccagatgtga c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" CDS 1679977..1680258 /gene="ylqH" /locus_tag="BSU_16080" /old_locus_tag="BSU16080" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type f: factor" /codon_start=1 /transl_table=11 /product="putative flagellar biosynthesis protein" /protein_id="NP_389490.1" /db_xref="EnsemblGenomes-Gn:BSU16080" /db_xref="EnsemblGenomes-Tr:CAB13481" /db_xref="GOA:O34867" /db_xref="InterPro:IPR004683" /db_xref="InterPro:IPR006135" /db_xref="InterPro:IPR029025" /db_xref="SubtiList:BG13407" /db_xref="UniProtKB/Swiss-Prot:O34867" /translation="MKEQTPIRKAVALHYDEQKDKAPRVIATGKGHVADNIIKEAKKA GVPIQEDRTLVELMRHLTVDDQIPEALYETVAEIFSFIYKLDESVKNKK*" gene 1679977..1680258 /gene="ylqH" /locus_tag="BSU_16080" /old_locus_tag="BSU16080" downshifts 1680090 /Source="Nicolas_upshifts" /id="D890" /incds=1 /nref=7 /ntot=136 /MaxReadThrough="4.03339" /MaxDrop="4.52065" /score="-6.81136789" /energy="-9.2" /TU="U1313,U1315" /idTUdmin="U1313" /TUdmin="-267" /isTUend="FALSE" S_feature 1680259..1680378 /Source="Nicolas_S_feature" /locus_tag="new_1680259_1680378" /HighExp="Cold, Lbstat, H2O2, Glu, Paraq, Mal, G135, GM 90, Oxctl, Fru" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigD, SigA" /TUshortPSig="1, 1" /TUlongSig="SigA" /TUlongPSig=1 /label="S582" promotor_-35 1680350..1680357 /Source="Nicolas_upshift_promotors" /id="U1317" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.55044955044955" /psig="0.999000999001" /xcortree=2227 /SigmaFactorBS="ttagaaggattaaaagattttgcatcgaacTGTAGACAattc ttccagtatTATTATAGAATGAAAGCGCAgtctattttagttttgttacataagttag g" /listShort="sucC, sucD, dprA, S583, topA" /listLong="trmFO, codV, clpQ, clpY, codY, S584, flgB, flgC, fliE, fliF, fliG, S585, fliH, fliI, fliJ, ylxF, fliK, flgD, flgE, ylzI, fliL, fliM, fliY, cheY, fliZ, fliP, fliQ, fliR, flhB, flhA, flhF, ylxH, cheB, cheA, cheW, cheC, cheD, sigD, ylxL, S586, rpsB, S587, tsf, S588, pyrH, frr, S589, uppS, cdsA, dxr, rseP, proS, S590, polC, S591, S592, S593, ylxS, nusA, ylxR, rplGA, infB, ylxP, rbfA, truB, ribC, S594, rpsO, S595, pnpA, S596, ylxY, mlpA" /label="promotor_-35" promotor_-10 1680371..1680390 /Source="Nicolas_upshift_promotors" /id="U1317" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.55044955044955" /psig="0.999000999001" /xcortree=2227 /SigmaFactorBS="ttagaaggattaaaagattttgcatcgaacTGTAGACAattc ttccagtatTATTATAGAATGAAAGCGCAgtctattttagttttgttacataagttag g" /listShort="sucC, sucD, dprA, S583, topA" /listLong="trmFO, codV, clpQ, clpY, codY, S584, flgB, flgC, fliE, fliF, fliG, S585, fliH, fliI, fliJ, ylxF, fliK, flgD, flgE, ylzI, fliL, fliM, fliY, cheY, fliZ, fliP, fliQ, fliR, flhB, flhA, flhF, ylxH, cheB, cheA, cheW, cheC, cheD, sigD, ylxL, S586, rpsB, S587, tsf, S588, pyrH, frr, S589, uppS, cdsA, dxr, rseP, proS, S590, polC, S591, S592, S593, ylxS, nusA, ylxR, rplGA, infB, ylxP, rbfA, truB, ribC, S594, rpsO, S595, pnpA, S596, ylxY, mlpA" /label="promotor_-10" upshifts 1680380 /Source="Nicolas_upshifts" /id="U1317" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.55044955044955" /psig="0.999000999001" /xcortree=2227 /SigmaFactorBS="ttagaaggattaaaagattttgcatcgaacTGTAGACAattc ttccagtatTATTATAGAATGAAAGCGCAgtctattttagttttgttacataagttag g" /listShort="sucC, sucD, dprA, S583, topA" /listLong="trmFO, codV, clpQ, clpY, codY, S584, flgB, flgC, fliE, fliF, fliG, S585, fliH, fliI, fliJ, ylxF, fliK, flgD, flgE, ylzI, fliL, fliM, fliY, cheY, fliZ, fliP, fliQ, fliR, flhB, flhA, flhF, ylxH, cheB, cheA, cheW, cheC, cheD, sigD, ylxL, S586, rpsB, S587, tsf, S588, pyrH, frr, S589, uppS, cdsA, dxr, rseP, proS, S590, polC, S591, S592, S593, ylxS, nusA, ylxR, rplGA, infB, ylxP, rbfA, truB, ribC, S594, rpsO, S595, pnpA, S596, ylxY, mlpA" CDS 1680431..1681588 /gene="sucC" /locus_tag="BSU_16090" /old_locus_tag="BSU16090" /EC_number="6.2.1.4" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2b: Function from indirect experimental evidences (e.g. phenotypes); PubMedId: 2548486, 22720735, 22751660; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="succinyl-CoA synthetase (beta subunit)" /protein_id="NP_389491.1" /db_xref="EnsemblGenomes-Gn:BSU16090" /db_xref="EnsemblGenomes-Tr:CAB13482" /db_xref="GOA:P80886" /db_xref="InterPro:IPR005809" /db_xref="InterPro:IPR005811" /db_xref="InterPro:IPR011761" /db_xref="InterPro:IPR013650" /db_xref="InterPro:IPR013815" /db_xref="InterPro:IPR016102" /db_xref="InterPro:IPR017866" /db_xref="SubtiList:BG12680" /db_xref="UniProtKB/Swiss-Prot:P80886" /translation="MNIHEYQGKEVLRKYGVSVPEGKVAFTAEEAVESAKSLSSSVYV VKAQIHAGGRGKAGGVKIAKSLDEVKAYAEELLGKTLVTHQTGPDGQVIKRLLIEEGC DIKKEYYIGLVLDRATSRIVLMASEEGGTEIEEVAEKTPEKIKKAVIDPAVGLQGYQA REIAFAINIPKELVGKAAKFMLGLYKAFVEKDCSIAEINPLVVTGDGNVMALDAKLNF DSNALYRQKDIMEYRDLDEEDPKEIEASKYDLSYISLDGNIGCMVNGAGLAMSTMDII KHYGGEPANFLDVGGGATAEKVTEAFKIILSDQNVKGIFVNIFGGIMKCDVIAEGVVE ATRQVGLTLPLVVRLEGTNVDLGKKILSESGLNITSAESMADGAQKIVSLV*" gene 1680431..1681588 /gene="sucC" /locus_tag="BSU_16090" /old_locus_tag="BSU16090" promotor_no_box complement(1680503..1680603) /Source="Nicolas_upshift_promotors" /id="U1318" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.864135864135864" /psig="0.0929070929070929" /xcortree=73 /SigmaFactorBS="ccagctttgcctcgaccgccagcatgaatttgagcctttacg acataaaccgagctggataagctctttgcactctcaactgcttcttctgctgtaaaag c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_no_box" upshifts complement(1680543) /Source="Nicolas_upshifts" /id="U1318" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.864135864135864" /psig="0.0929070929070929" /xcortree=73 /SigmaFactorBS="ccagctttgcctcgaccgccagcatgaatttgagcctttacg acataaaccgagctggataagctctttgcactctcaactgcttcttctgctgtaaaag c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" CDS 1681617..1682519 /gene="sucD" /locus_tag="BSU_16100" /old_locus_tag="BSU16100" /EC_number="6.2.1.4" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2b: Function from indirect experimental evidences (e.g. phenotypes); PubMedId: 9643546, 22720735, 22751660; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="succinyl-CoA synthetase (alpha subunit)" /protein_id="NP_389492.1" /db_xref="EnsemblGenomes-Gn:BSU16100" /db_xref="EnsemblGenomes-Tr:CAB13483" /db_xref="GOA:P80865" /db_xref="InterPro:IPR003781" /db_xref="InterPro:IPR005810" /db_xref="InterPro:IPR005811" /db_xref="InterPro:IPR016102" /db_xref="InterPro:IPR017440" /db_xref="InterPro:IPR033847" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG12681" /db_xref="UniProtKB/Swiss-Prot:P80865" /translation="MSVFINKDTRVIVQGITGSTALFHTKQMLEYGTNIVGGVTPGKG GTEAEGVPVFNTVAEAVQTTGANASVIYVPAPFAADAIMEAVDAELDLVICITEHIPV LDMVKVKRFMEGKKTRLIGPNCPGVITPEECKIGIMPGYIHKKGHVGVVSRSGTLTYE AVHQLSEAGVGQSTAVGIGGDPVNGTNFIDVLKAFNEDPDTHAVIMIGEIGGTAEEEA AEWVKANMTKPVVGFIGGKTAPPGKRMGHAGAIISGGKGTADEKIKTLNACGIEVAET PSVMGETLIKVLKEKNLFETCKTH*" gene 1681617..1682519 /gene="sucD" /locus_tag="BSU_16100" /old_locus_tag="BSU16100" downshifts 1682509 /Source="Nicolas_upshifts" /id="D891" /incds=0 /nref=94 /ntot=208 /MaxReadThrough="5.40077" /MaxDrop="4.8878" /score="9.51199539" /energy="-15" /TU="U1317" /idTUdmin="U1315" /TUdmin=2130 /isTUend="FALSE" CDS 1682580..1683473 /gene="dprA" /locus_tag="BSU_16110" /old_locus_tag="BSU16110" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:16014871, 16978360, 17803906, 18045469, 7768823, 23779106, 25138221, 28618091" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16014871, 16978360, 17803906, 18045469, 7768823, 23779106, 25138221, 28618091; Product type f: factor" /codon_start=1 /transl_table=11 /product="DNA processing Smf single strand binding protein" /protein_id="NP_389493.1" /db_xref="EnsemblGenomes-Gn:BSU16110" /db_xref="EnsemblGenomes-Tr:CAB13484" /db_xref="GOA:P39813" /db_xref="InterPro:IPR003488" /db_xref="SubtiList:BG11006" /db_xref="UniProtKB/Swiss-Prot:P39813" /translation="MDQAAVCLTICRINQLLSPSLLLKWWKADPSMSLTSPVLQTVTR DQIKAAALKNEIEQFYPKLPRVLAAYREQGINTIPISSKQYPFWLKSIYDPPAVLFAK GDMTLLSKGRKIGIVGTRNPTAYGKQVVNHLTKEICRKGWVIVSGLASGIDGMSHAAS IKAKGRTIGVIAGGFQHIYPRENLQLADHMAKHHILLSEHPPETKPQKWHFPMRNRII SGLSEGVIVVQGKEKSGSLITAYQALEQGREVFAVPGSLFDPYAGGPIKLIQQGAKAI WSAEDIFEELPERNVQYTEPF*" gene 1682580..1683473 /gene="dprA" /locus_tag="BSU_16110" /old_locus_tag="BSU16110" promotor_-35 1683479..1683486 /Source="Nicolas_upshift_promotors" /id="U1319" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.839160839160839" /psig=1 /xcortree=1880 /SigmaFactorBS="acgttcaatatacggaacccttttgaattatCGTTTGACaaa cggtattgtaaTATTTAATAATAGTGAGGATttaaagttgcatattgttttctattta a" /listShort="S583, topA, trmFO" /listLong="codV, clpQ, clpY, codY, S584, flgB, flgC, fliE, fliF, fliG, S585, fliH, fliI, fliJ, ylxF, fliK, flgD, flgE, ylzI, fliL, fliM, fliY, cheY, fliZ, fliP, fliQ, fliR, flhB, flhA, flhF, ylxH, cheB, cheA, cheW, cheC, cheD, sigD, ylxL, S586, rpsB, S587, tsf, S588, pyrH, frr, S589, uppS, cdsA, dxr, rseP, proS, S590, polC, S591, S592, S593, ylxS, nusA, ylxR, rplGA, infB, ylxP, rbfA, truB, ribC, S594, rpsO, S595, pnpA, S596, ylxY, mlpA" /label="promotor_-35" promotor_-10 1683501..1683520 /Source="Nicolas_upshift_promotors" /id="U1319" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.839160839160839" /psig=1 /xcortree=1880 /SigmaFactorBS="acgttcaatatacggaacccttttgaattatCGTTTGACaaa cggtattgtaaTATTTAATAATAGTGAGGATttaaagttgcatattgttttctattta a" /listShort="S583, topA, trmFO" /listLong="codV, clpQ, clpY, codY, S584, flgB, flgC, fliE, fliF, fliG, S585, fliH, fliI, fliJ, ylxF, fliK, flgD, flgE, ylzI, fliL, fliM, fliY, cheY, fliZ, fliP, fliQ, fliR, flhB, flhA, flhF, ylxH, cheB, cheA, cheW, cheC, cheD, sigD, ylxL, S586, rpsB, S587, tsf, S588, pyrH, frr, S589, uppS, cdsA, dxr, rseP, proS, S590, polC, S591, S592, S593, ylxS, nusA, ylxR, rplGA, infB, ylxP, rbfA, truB, ribC, S594, rpsO, S595, pnpA, S596, ylxY, mlpA" /label="promotor_-10" S_feature 1683508..1683660 /Source="Nicolas_S_feature" /locus_tag="new_1683508_1683660" /HighExp="dia15, H2O2, G/S, Paraq, Diami, S1, Oxctl, LBGexp, C30, S2" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.111279" /TUshortSig="SigA, SigA" /TUshortPSig="1, 0.999" /TUlongSig="SigD, SigA, SigA" /TUlongPSig="1, 1, 1" /label="S583" upshifts 1683508 /Source="Nicolas_upshifts" /id="U1319" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.839160839160839" /psig=1 /xcortree=1880 /SigmaFactorBS="acgttcaatatacggaacccttttgaattatCGTTTGACaaa cggtattgtaaTATTTAATAATAGTGAGGATttaaagttgcatattgttttctattta a" /listShort="S583, topA, trmFO" /listLong="codV, clpQ, clpY, codY, S584, flgB, flgC, fliE, fliF, fliG, S585, fliH, fliI, fliJ, ylxF, fliK, flgD, flgE, ylzI, fliL, fliM, fliY, cheY, fliZ, fliP, fliQ, fliR, flhB, flhA, flhF, ylxH, cheB, cheA, cheW, cheC, cheD, sigD, ylxL, S586, rpsB, S587, tsf, S588, pyrH, frr, S589, uppS, cdsA, dxr, rseP, proS, S590, polC, S591, S592, S593, ylxS, nusA, ylxR, rplGA, infB, ylxP, rbfA, truB, ribC, S594, rpsO, S595, pnpA, S596, ylxY, mlpA" CDS 1683661..1685736 /gene="topA" /locus_tag="BSU_16120" /old_locus_tag="BSU16120" /EC_number="5.99.1.2" /function="16.3: Control" /function="16.6: Maintain" /function="16.9: Replicate" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:9580687, 12682299, 16585761, 23133654" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9580687, 12682299, 16585761, 23133654; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="DNA topoisomerase I" /protein_id="NP_389494.1" /db_xref="EnsemblGenomes-Gn:BSU16120" /db_xref="EnsemblGenomes-Tr:CAB13485" /db_xref="GOA:P39814" /db_xref="InterPro:IPR000380" /db_xref="InterPro:IPR003601" /db_xref="InterPro:IPR003602" /db_xref="InterPro:IPR005733" /db_xref="InterPro:IPR006171" /db_xref="InterPro:IPR013497" /db_xref="InterPro:IPR013498" /db_xref="InterPro:IPR013825" /db_xref="InterPro:IPR023405" /db_xref="InterPro:IPR023406" /db_xref="InterPro:IPR028612" /db_xref="InterPro:IPR034149" /db_xref="SubtiList:BG11007" /db_xref="UniProtKB/Swiss-Prot:P39814" /translation="MSDYLVIVESPAKAKTIERYLGKKYKVKASMGHVRDLPKSQMGV DIEQNFEPKYITIRGKGPVLKELKTAAKKAKKVYLAADPDREGEAIAWHLAHSLDLDL NSDCRVVFNEITKDAIKESFKHPRMINMDLVDAQQARRILDRLVGYKISPILWKKVKK GLSAGRVQSVALRLIIDREKEINDFKPEEYWTIDGTFLKGQETFEASFFGKNGKKLPL NSEADVKEILSQLKGNQYTVEKVTKKERKRNPALPFTTSTLQQEAARKLNFRAKKTMM IAQQLYEGIDLGREGTVGLITYMRTDSTRISNTAVDEAAAFIDQTYGKEFLGGKRKPA KKNENAQDAHEAIRPTSVLRKPSELKAVLGRDQMRLYKLIWERFVASQMAPAVLDTMS VDLTNNGLTFRANGSKVKFSGFMKVYVEGKDDQMEEKDRMLPDLQEGDTVLSKDIEPE QHFTQPPPRYTEARLVKTLEERGIGRPSTYAPTLDTIQRRGYVALDNKRFVPTELGQI VLDLIMEFFPEIINVEFTAKMERDLDHVEEGNTEWVKIIDNFYTDFEKRVKKAESEMK EVEIEPEYAGEDCELCSSPMVYKMGRYGKFLACSNFPDCRNTKPIVKQIGVKCPSCGE GNIVERKSKKKRVFYGCDRYPDCEFVSWDKPIERKCPKCGKMLVEKKLKKGIQVQCVE CDYKEEPQK*" gene 1683661..1685736 /gene="topA" /locus_tag="BSU_16120" /old_locus_tag="BSU16120" downshifts 1685706 /Source="Nicolas_upshifts" /id="D892" /incds=0 /nref=48 /ntot=173 /MaxReadThrough="5.66787" /MaxDrop="4.5486" /score="0.939045188" /energy="-13.2" /TU="U1319" /idTUdmin="U1317" /TUdmin="-19" /isTUend="TRUE" promotor_-35 1685768..1685773 /Source="Nicolas_upshift_promotors" /id="U1320" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.588411588411588" /psig="0.588411588411588" /xcortree=1017 /SigmaFactorBS="aagaaccacagaagtagcggtgagcagggtcttgctcacctt ctttgtGTGTTAaaagaaggccttgaaTAATAAACTAGGAGATGTGaaagatgaacca a" /listShort="trmFO, codV, clpQ, clpY, codY" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 1685780 /Source="Nicolas_upshifts" /id="U1320" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.588411588411588" /psig="0.588411588411588" /xcortree=1017 /SigmaFactorBS="aagaaccacagaagtagcggtgagcagggtcttgctcacctt ctttgtGTGTTAaaagaaggccttgaaTAATAAACTAGGAGATGTGaaagatgaacca a" /listShort="trmFO, codV, clpQ, clpY, codY" /GFF_Attribute="listLong" promotor_-10 1685789..1685807 /Source="Nicolas_upshift_promotors" /id="U1320" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.588411588411588" /psig="0.588411588411588" /xcortree=1017 /SigmaFactorBS="aagaaccacagaagtagcggtgagcagggtcttgctcacctt ctttgtGTGTTAaaagaaggccttgaaTAATAAACTAGGAGATGTGaaagatgaacca a" /listShort="trmFO, codV, clpQ, clpY, codY" /GFF_Attribute="listLong" /label="promotor_-10" CDS 1685812..1687119 /gene="trmFO" /locus_tag="BSU_16130" /old_locus_tag="BSU16130" /EC_number="2.1.1.74" /function="16.2: Construct biomass (Anabolism)" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:16027442, 21561081, 23095745, 23157377, 27825927, 28745052" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16027442, 21561081, 23095745, 23157377, 27825927, 28745052; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="tRNA:m(5)U-54 methyltransferase" /protein_id="NP_389495.1" /db_xref="EnsemblGenomes-Gn:BSU16130" /db_xref="EnsemblGenomes-Tr:CAB13486" /db_xref="GOA:P39815" /db_xref="InterPro:IPR002218" /db_xref="InterPro:IPR004417" /db_xref="InterPro:IPR020595" /db_xref="InterPro:IPR036188" /db_xref="SubtiList:BG11008" /db_xref="UniProtKB/Swiss-Prot:P39815" /translation="MNQQTVNVIGAGLAGSEAAWQLAKRGIQVKLYEMRPVKQTPAHH TDKFAELVCSNSLRSNTLANAVGVLKEEMRALDSAIIAAADECSVPAGGALAVDRHEF AASVTNRVKNHPNVTVINEEVTEIPEGPTIIATGPLTSESLSAQLKELTGEDYLYFYD AAAPIVEKDSLDMDKVYLKSRYDKGEAAYLNCPMTEEEFDRFHEALTSAETVPLKEFE KEIFFEGCMPIEVMAKRGKKTMLFGPMKPVGLEHPVTGKRPYAVVQLRQDDAAGTLYN IVGFQTHLKWGDQKEVLKLIPGLENVEIVRYGVMHRNTFINSPSLLKPTYQFKNRSDL FFAGQMTGVEGYVESAASGLVAGINAAKLVLGEELVIFPQETAIGSMAHYITTTNQKN FQPMNANFGLLKELPVKIKNKKERNEQYANRAIETIQTISKTI*" gene 1685812..1687119 /gene="trmFO" /locus_tag="BSU_16130" /old_locus_tag="BSU16130" promotor_-35 1687125..1687129 /Source="Nicolas_upshift_promotors" /id="U1321" /multdbtbs="SigA" /comp="M16" /sig="SigA" /pcomp="0.626373626373626" /psig="0.998001998001998" /xcortree=2482 /SigmaFactorBS="caaacaatttcgaaaacaatataggtattGATTGcaacctga gcgcgattTGTGATACCATTTAAAAGCCcttcctggggaggtattaggcatggagaat g" /listShort="codV, clpQ, clpY, codY, S584, flgB, flgC, fliE, fliF, fliG, S585, fliH, fliI, fliJ, ylxF, fliK, flgD, flgE, ylzI, fliL, fliM, fliY, cheY, fliZ, fliP, fliQ, fliR, flhB, flhA, flhF, ylxH, cheB, cheA, cheW, cheC, cheD, sigD" /listLong="ylxL, S586, rpsB, S587, tsf, S588, pyrH, frr, S589, uppS, cdsA, dxr, rseP, proS, S590, polC, S591, S592, S593, ylxS, nusA, ylxR, rplGA, infB, ylxP, rbfA, truB, ribC, S594, rpsO, S595, pnpA, S596, ylxY, mlpA" /label="promotor_-35" promotor_-10 1687146..1687165 /Source="Nicolas_upshift_promotors" /id="U1321" /multdbtbs="SigA" /comp="M16" /sig="SigA" /pcomp="0.626373626373626" /psig="0.998001998001998" /xcortree=2482 /SigmaFactorBS="caaacaatttcgaaaacaatataggtattGATTGcaacctga gcgcgattTGTGATACCATTTAAAAGCCcttcctggggaggtattaggcatggagaat g" /listShort="codV, clpQ, clpY, codY, S584, flgB, flgC, fliE, fliF, fliG, S585, fliH, fliI, fliJ, ylxF, fliK, flgD, flgE, ylzI, fliL, fliM, fliY, cheY, fliZ, fliP, fliQ, fliR, flhB, flhA, flhF, ylxH, cheB, cheA, cheW, cheC, cheD, sigD" /listLong="ylxL, S586, rpsB, S587, tsf, S588, pyrH, frr, S589, uppS, cdsA, dxr, rseP, proS, S590, polC, S591, S592, S593, ylxS, nusA, ylxR, rplGA, infB, ylxP, rbfA, truB, ribC, S594, rpsO, S595, pnpA, S596, ylxY, mlpA" /label="promotor_-10" upshifts 1687156 /Source="Nicolas_upshifts" /id="U1321" /multdbtbs="SigA" /comp="M16" /sig="SigA" /pcomp="0.626373626373626" /psig="0.998001998001998" /xcortree=2482 /SigmaFactorBS="caaacaatttcgaaaacaatataggtattGATTGcaacctga gcgcgattTGTGATACCATTTAAAAGCCcttcctggggaggtattaggcatggagaat g" /listShort="codV, clpQ, clpY, codY, S584, flgB, flgC, fliE, fliF, fliG, S585, fliH, fliI, fliJ, ylxF, fliK, flgD, flgE, ylzI, fliL, fliM, fliY, cheY, fliZ, fliP, fliQ, fliR, flhB, flhA, flhF, ylxH, cheB, cheA, cheW, cheC, cheD, sigD" /listLong="ylxL, S586, rpsB, S587, tsf, S588, pyrH, frr, S589, uppS, cdsA, dxr, rseP, proS, S590, polC, S591, S592, S593, ylxS, nusA, ylxR, rplGA, infB, ylxP, rbfA, truB, ribC, S594, rpsO, S595, pnpA, S596, ylxY, mlpA" CDS 1687187..1688101 /gene="codV" /locus_tag="BSU_16140" /old_locus_tag="BSU16140" /function="16.9: Replicate" /function="16.8: Protect" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:10498718, 11208805, 16553881, 16597952, 21239579" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10498718, 11208805, 16553881, 16597952, 21239579; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="site-specific tyrosine recombinase for chromosome partitioning" /protein_id="NP_389496.1" /db_xref="EnsemblGenomes-Gn:BSU16140" /db_xref="EnsemblGenomes-Tr:CAB13487" /db_xref="GOA:P39776" /db_xref="InterPro:IPR002104" /db_xref="InterPro:IPR004107" /db_xref="InterPro:IPR010998" /db_xref="InterPro:IPR011010" /db_xref="InterPro:IPR011931" /db_xref="InterPro:IPR013762" /db_xref="InterPro:IPR023009" /db_xref="SubtiList:BG10965" /db_xref="UniProtKB/Swiss-Prot:P39776" /translation="MENVKNFVKLFVEYLQIEKNYSQYTIVNYVDSIEEFETFLRVQG INGFEEAAYQDTRIFLTEAYEKGLSRRTISKKISALRSFYKFLMREKLIEENPFQLVH LPKQEKRIPKFLYQKELEELFEVSDISQPAGMRDQALLELLYATGMRVSECCSITIND VDLFMDTVLVHGKGKKQRYIPFGSYAREALKVYMNSGRQCLLMKAKEPHDLLFVNQRG GPLTARGIRHILSGLVQKASSTLHIHPHMLRHTFATHLLNEGADLRSVQELLGHSNLS STQIYTHVSKEMLRNTYMSHHPRAFKKN*" gene 1687187..1688101 /gene="codV" /locus_tag="BSU_16140" /old_locus_tag="BSU16140" promotor_-35 1687226..1687230 /Source="Nicolas_upshift_promotors" /id="U1322" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.525474525474525" /psig="0.994005994005994" /xcortree=2472 /SigmaFactorBS="aggcatggagaatgttaagaatttcgtaaagttattcgttga aTATTTacaaattgaaaaaaaTTATTCACAATATACTATTGtgaattatgtggattca a" /listShort="clpQ, clpY, codY, S584" /listLong="flgB, flgC, fliE, fliF, fliG, S585, fliH, fliI, fliJ, ylxF, fliK, flgD, flgE, ylzI, fliL, fliM, fliY, cheY, fliZ, fliP, fliQ, fliR, flhB, flhA, flhF, ylxH, cheB, cheA, cheW, cheC, cheD, sigD, ylxL, S586, rpsB, S587, tsf, S588, pyrH, frr, S589, uppS, cdsA, dxr, rseP, proS, S590, polC" /label="promotor_-35" upshifts 1687243 /Source="Nicolas_upshifts" /id="U1322" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.525474525474525" /psig="0.994005994005994" /xcortree=2472 /SigmaFactorBS="aggcatggagaatgttaagaatttcgtaaagttattcgttga aTATTTacaaattgaaaaaaaTTATTCACAATATACTATTGtgaattatgtggattca a" /listShort="clpQ, clpY, codY, S584" /listLong="flgB, flgC, fliE, fliF, fliG, S585, fliH, fliI, fliJ, ylxF, fliK, flgD, flgE, ylzI, fliL, fliM, fliY, cheY, fliZ, fliP, fliQ, fliR, flhB, flhA, flhF, ylxH, cheB, cheA, cheW, cheC, cheD, sigD, ylxL, S586, rpsB, S587, tsf, S588, pyrH, frr, S589, uppS, cdsA, dxr, rseP, proS, S590, polC" promotor_-10 1687246..1687265 /Source="Nicolas_upshift_promotors" /id="U1322" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.525474525474525" /psig="0.994005994005994" /xcortree=2472 /SigmaFactorBS="aggcatggagaatgttaagaatttcgtaaagttattcgttga aTATTTacaaattgaaaaaaaTTATTCACAATATACTATTGtgaattatgtggattca a" /listShort="clpQ, clpY, codY, S584" /listLong="flgB, flgC, fliE, fliF, fliG, S585, fliH, fliI, fliJ, ylxF, fliK, flgD, flgE, ylzI, fliL, fliM, fliY, cheY, fliZ, fliP, fliQ, fliR, flhB, flhA, flhF, ylxH, cheB, cheA, cheW, cheC, cheD, sigD, ylxL, S586, rpsB, S587, tsf, S588, pyrH, frr, S589, uppS, cdsA, dxr, rseP, proS, S590, polC" /label="promotor_-10" CDS 1688114..1688659 /gene="clpQ" /locus_tag="BSU_16150" /old_locus_tag="BSU16150" /EC_number="3.4.25.2" /function="16.6: Maintain" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:11179218, 12032294, 12805205, 15983416, 17979190, 18689473, 21546913" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11179218, 12032294, 12805205, 15983416, 17979190, 18689473, 21546913; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="two-component ATP-dependent protease (N-terminalserine protease)" /protein_id="NP_389497.1" /db_xref="EnsemblGenomes-Gn:BSU16150" /db_xref="EnsemblGenomes-Tr:CAB13488" /db_xref="GOA:P39070" /db_xref="InterPro:IPR001353" /db_xref="InterPro:IPR022281" /db_xref="InterPro:IPR023333" /db_xref="InterPro:IPR029055" /db_xref="PDB:1YYF" /db_xref="PDB:2Z3A" /db_xref="PDB:2Z3B" /db_xref="SubtiList:BG10966" /db_xref="UniProtKB/Swiss-Prot:P39070" /translation="MSSFHATTIFAVQHKGRSAMSGDGQVTFGQAVVMKHTARKVRKL FNGKVLAGFAGSVADAFTLFEKFEAKLEEYNGNLKRAAVELAKEWRSDKVLRKLEAML IVMNQDTLLLVSGTGEVIEPDDGILAIGSGGNYALAAGRALKKHAGESMSASEIARAA LETAGEICVYTNDQIILEELE*" gene 1688114..1688659 /gene="clpQ" /locus_tag="BSU_16150" /old_locus_tag="BSU16150" CDS 1688676..1690079 /gene="clpY" /locus_tag="BSU_16160" /old_locus_tag="BSU16160" /function="16.3: Control" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:11179218, 12032294, 12805205, 15983416, 17979190, 18689473, 21546913" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11179218, 12032294, 12805205, 15983416, 17979190, 18689473, 21546913; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="two-component ATP-dependent protease (ATPase andchaperone)" /protein_id="NP_389498.1" /db_xref="EnsemblGenomes-Gn:BSU16160" /db_xref="EnsemblGenomes-Tr:CAB13489" /db_xref="GOA:P39778" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR003959" /db_xref="InterPro:IPR004491" /db_xref="InterPro:IPR019489" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG10967" /db_xref="UniProtKB/Swiss-Prot:P39778" /translation="MEKKPLTPRQIVDRLDQYIVGQQNAKKAVAVALRNRYRRSLLDE KLKDEVVPKNILMMGPTGVGKTEIARRIAKLSGAPFIKIEATKFTEVGYVGRDVESMV RDLVETSVRLIKEEKMNEVKEQAEENANKRIVRLLVPGKKKQSGVKNPFEMFFGGSQP NGEDEAESQEEANIEEKRKRMAHQLALGELEDYYVTVEVEEQQPSMFDMLQGSGMEQM GMNMQDALSGLMPKKKKRRKMTVREARKVLTNEEASKLIDMDEVGQEAVQRAEESGII FIDEIDKIAKNGGASSSADVSREGVQRDILPIVEGSTVVTKYGSVKTDHVLFIAAGAF HMAKPSDLIPELQGRFPIRVELNKLTVDDFVRILVEPDNALLKQYQALLQTEGISLEF SDEAIHKIAEVAYHVNQDTDNIGARRLHTILERLLEDLSFEAPDVTMEKITITPQYVE EKLGTIAKNKDLSQFIL*" gene 1688676..1690079 /gene="clpY" /locus_tag="BSU_16160" /old_locus_tag="BSU16160" CDS 1690119..1690898 /gene="codY" /locus_tag="BSU_16170" /old_locus_tag="BSU16170" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:9515911, 10094682, 10231480, 10803944, 10809682, 16488888, 17993518, 21856856, 24843172, 26473603, 27596595, 28011634" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9515911, 10094682, 10231480, 10803944, 10809682, 16488888, 17993518, 21856856, 24843172, 26473603, 27596595, 28011634; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator, GTP and BCAA-dependent" /protein_id="NP_389499.1" /db_xref="EnsemblGenomes-Gn:BSU16170" /db_xref="EnsemblGenomes-Tr:CAB13490" /db_xref="GOA:P39779" /db_xref="InterPro:IPR010312" /db_xref="InterPro:IPR013198" /db_xref="InterPro:IPR014154" /db_xref="InterPro:IPR029016" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="PDB:2B0L" /db_xref="PDB:2B18" /db_xref="PDB:2GX5" /db_xref="PDB:2HGV" /db_xref="PDB:5LNH" /db_xref="PDB:5LOE" /db_xref="PDB:5LOJ" /db_xref="PDB:5LOO" /db_xref="SubtiList:BG10968" /db_xref="UniProtKB/Swiss-Prot:P39779" /translation="MALLQKTRIINSMLQAAAGKPVNFKEMAETLRDVIDSNIFVVSR RGKLLGYSINQQIENDRMKKMLEDRQFPEEYTKNLFNVPETSSNLDINSEYTAFPVEN RDLFQAGLTTIVPIIGGGERLGTLILSRLQDQFNDDDLILAEYGATVVGMEILREKAE EIEEEARSKAVVQMAISSLSYSELEAIEHIFEELDGNEGLLVASKIADRVGITRSVIV NALRKLESAGVIESRSLGMKGTYIKVLNNKFLIELENLKSH*" gene 1690119..1690898 /gene="codY" /locus_tag="BSU_16170" /old_locus_tag="BSU16170" downshifts 1690873 /Source="Nicolas_upshifts" /id="D893" /incds=0 /nref=6 /ntot=130 /MaxReadThrough="5.35492" /MaxDrop="5.90286" /score="-6.99307778" /energy="-4.2" /TU="U1321,U1322" /idTUdmin="U1320" /TUdmin=0 /isTUend="TRUE" downshifts 1690917 /Source="Nicolas_upshifts" /id="D894" /incds=0 /nref=1 /ntot=104 /MaxReadThrough="4.95658" /MaxDrop="4.85551" /score="-6.99307778" /energy="-4.2" /TU="U1321,U1322" /idTUdmin="U1320" /TUdmin=44 /isTUend="FALSE" promotor_-35 1691018..1691025 /Source="Nicolas_upshift_promotors" /id="U1323" /multdbtbs="SigD" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2824 /SigmaFactorBS="gtaataattttaataaattttgcatttttCTTCAAAAagttt caaaaatGCCGAAAAGAAAGGAGAAAaaacagaaattctgctattttcaggcttatat c" /listShort="S584, flgB, flgC, fliE, fliF, fliG, S585, fliH, fliI, fliJ, ylxF, fliK, flgD, flgE, ylzI, fliL, fliM, fliY, cheY, fliZ, fliP, fliQ, fliR, flhB, flhA, flhF, ylxH, cheB, cheA, cheW, cheC, cheD, sigD, ylxL" /listLong="S586, rpsB, S587, tsf, S588, pyrH, frr, S589, uppS, cdsA, dxr, rseP, proS, S590, polC, S591, S592, S593, ylxS, nusA, ylxR, rplGA, infB, ylxP, rbfA, truB, ribC, S594, rpsO, S595, pnpA, S596, ylxY, mlpA" /label="promotor_-35" promotor_-10 1691038..1691056 /Source="Nicolas_upshift_promotors" /id="U1323" /multdbtbs="SigD" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2824 /SigmaFactorBS="gtaataattttaataaattttgcatttttCTTCAAAAagttt caaaaatGCCGAAAAGAAAGGAGAAAaaacagaaattctgctattttcaggcttatat c" /listShort="S584, flgB, flgC, fliE, fliF, fliG, S585, fliH, fliI, fliJ, ylxF, fliK, flgD, flgE, ylzI, fliL, fliM, fliY, cheY, fliZ, fliP, fliQ, fliR, flhB, flhA, flhF, ylxH, cheB, cheA, cheW, cheC, cheD, sigD, ylxL" /listLong="S586, rpsB, S587, tsf, S588, pyrH, frr, S589, uppS, cdsA, dxr, rseP, proS, S590, polC, S591, S592, S593, ylxS, nusA, ylxR, rplGA, infB, ylxP, rbfA, truB, ribC, S594, rpsO, S595, pnpA, S596, ylxY, mlpA" /label="promotor_-10" S_feature 1691049..1691202 /Source="Nicolas_S_feature" /locus_tag="new_1691049_1691202" /HighExp="C30, GM 90, GM 25, Cold, GM 15, GM 10, MG 150, GM-0.2, LBGstat, GM-0.1" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigD, SigA, SigA" /TUshortPSig="1, 0.994, 0.998" /TUlongSig="SigA, SigA, SigD, SigA, SigA" /TUlongPSig="1, 0.999, 1, 1, 1" /label="S584" upshifts 1691049 /Source="Nicolas_upshifts" /id="U1323" /multdbtbs="SigD" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2824 /SigmaFactorBS="gtaataattttaataaattttgcatttttCTTCAAAAagttt caaaaatGCCGAAAAGAAAGGAGAAAaaacagaaattctgctattttcaggcttatat c" /listShort="S584, flgB, flgC, fliE, fliF, fliG, S585, fliH, fliI, fliJ, ylxF, fliK, flgD, flgE, ylzI, fliL, fliM, fliY, cheY, fliZ, fliP, fliQ, fliR, flhB, flhA, flhF, ylxH, cheB, cheA, cheW, cheC, cheD, sigD, ylxL" /listLong="S586, rpsB, S587, tsf, S588, pyrH, frr, S589, uppS, cdsA, dxr, rseP, proS, S590, polC, S591, S592, S593, ylxS, nusA, ylxR, rplGA, infB, ylxP, rbfA, truB, ribC, S594, rpsO, S595, pnpA, S596, ylxY, mlpA" promotor_-35 1691177..1691184 /Source="Nicolas_upshift_promotors" /id="U1324" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.748251748251748" /psig="0.998001998001998" /xcortree=2791 /SigmaFactorBS="gataattgtgaggacatttttttacacgaacttCATAGACTt tatgcctgttattTCTTACAATAAGCATATAGTtttacaattctcgacaaggatattg a" /listShort="flgB, flgC, fliE, fliF, fliG, S585, fliH, fliI, fliJ, ylxF, fliK, flgD, flgE, ylzI, fliL, fliM, fliY, cheY, fliZ, fliP, fliQ, fliR, flhB, flhA, flhF, ylxH, cheB, cheA, cheW, cheC, cheD, sigD, ylxL, S586, rpsB, S587, tsf, S588, pyrH, frr, S589, uppS, cdsA, dxr, rseP, proS, S590, polC, S591" /listLong="S592, S593, ylxS, nusA, ylxR, rplGA, infB, ylxP, rbfA, truB, ribC, S594, rpsO, S595, pnpA, S596, ylxY, mlpA" /label="promotor_-35" promotor_-10 1691199..1691218 /Source="Nicolas_upshift_promotors" /id="U1324" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.748251748251748" /psig="0.998001998001998" /xcortree=2791 /SigmaFactorBS="gataattgtgaggacatttttttacacgaacttCATAGACTt tatgcctgttattTCTTACAATAAGCATATAGTtttacaattctcgacaaggatattg a" /listShort="flgB, flgC, fliE, fliF, fliG, S585, fliH, fliI, fliJ, ylxF, fliK, flgD, flgE, ylzI, fliL, fliM, fliY, cheY, fliZ, fliP, fliQ, fliR, flhB, flhA, flhF, ylxH, cheB, cheA, cheW, cheC, cheD, sigD, ylxL, S586, rpsB, S587, tsf, S588, pyrH, frr, S589, uppS, cdsA, dxr, rseP, proS, S590, polC, S591" /listLong="S592, S593, ylxS, nusA, ylxR, rplGA, infB, ylxP, rbfA, truB, ribC, S594, rpsO, S595, pnpA, S596, ylxY, mlpA" /label="promotor_-10" upshifts 1691204 /Source="Nicolas_upshifts" /id="U1324" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.748251748251748" /psig="0.998001998001998" /xcortree=2791 /SigmaFactorBS="gataattgtgaggacatttttttacacgaacttCATAGACTt tatgcctgttattTCTTACAATAAGCATATAGTtttacaattctcgacaaggatattg a" /listShort="flgB, flgC, fliE, fliF, fliG, S585, fliH, fliI, fliJ, ylxF, fliK, flgD, flgE, ylzI, fliL, fliM, fliY, cheY, fliZ, fliP, fliQ, fliR, flhB, flhA, flhF, ylxH, cheB, cheA, cheW, cheC, cheD, sigD, ylxL, S586, rpsB, S587, tsf, S588, pyrH, frr, S589, uppS, cdsA, dxr, rseP, proS, S590, polC, S591" /listLong="S592, S593, ylxS, nusA, ylxR, rplGA, infB, ylxP, rbfA, truB, ribC, S594, rpsO, S595, pnpA, S596, ylxY, mlpA" CDS 1691278..1691667 /gene="flgB" /locus_tag="BSU_16180" /old_locus_tag="BSU16180" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 1905667, 2129540, 2181149, 9657996, 17850253, 25843804; Product type s: structure" /codon_start=1 /transl_table=11 /product="flagellar component of cell-proximal portion of basal-body rod" /protein_id="NP_389500.1" /db_xref="EnsemblGenomes-Gn:BSU16180" /db_xref="EnsemblGenomes-Tr:CAB13491" /db_xref="GOA:P24500" /db_xref="InterPro:IPR001444" /db_xref="InterPro:IPR006300" /db_xref="InterPro:IPR019776" /db_xref="SubtiList:BG10237" /db_xref="UniProtKB/Swiss-Prot:P24500" /translation="MSLFSGTIQNLENALSRADIKQKVITNNIANIDTPNYKAKKVSF QNLLDQESSRLEAIKTDYRHVDFSDTDSNYSIVASGDTSYQQNGNNVDVDKEMTELAQ NQINYQALVERMNGKFNSLKTVLTGGK*" gene 1691278..1691667 /gene="flgB" /locus_tag="BSU_16180" /old_locus_tag="BSU16180" CDS 1691667..1692119 /gene="flgC" /locus_tag="BSU_16190" /old_locus_tag="BSU16190" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 1905667, 2129540, 2181149, 9657996; Product type s: structure" /codon_start=1 /transl_table=11 /product="flagellar component of cell-proximal portion of basal-body rod" /protein_id="NP_389501.1" /db_xref="EnsemblGenomes-Gn:BSU16190" /db_xref="EnsemblGenomes-Tr:CAB13492" /db_xref="GOA:P24501" /db_xref="InterPro:IPR001444" /db_xref="InterPro:IPR006299" /db_xref="InterPro:IPR010930" /db_xref="InterPro:IPR019776" /db_xref="SubtiList:BG10238" /db_xref="UniProtKB/Swiss-Prot:P24501" /translation="MTAFHSLNVSASALTAQRVRMDVVSSNLANMDTTRAKQVNGEWV PYRRKMVSLQSKGESFSSILNSQMSGSGNAGNGVKVSKITEDDSDFNLVYDPTDPDAN AEGYVQKPNVDPLKEMVDLVSSTRSYEANVTAMNATKGMLMKALEIGK*" gene 1691667..1692119 /gene="flgC" /locus_tag="BSU_16190" /old_locus_tag="BSU16190" CDS 1692130..1692450 /gene="fliE" /locus_tag="BSU_16200" /old_locus_tag="BSU16200" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 11133968, 1551848, 1905667, 2544561, 9161424, 11133968, 15136044; Product type s: structure" /codon_start=1 /transl_table=11 /product="flagellar basal body protein" /protein_id="NP_389502.1" /db_xref="EnsemblGenomes-Gn:BSU16200" /db_xref="EnsemblGenomes-Tr:CAB13493" /db_xref="GOA:P24502" /db_xref="InterPro:IPR001624" /db_xref="SubtiList:BG10239" /db_xref="UniProtKB/Swiss-Prot:P24502" /translation="MINAISPFQVQNTQNTQNATNQVNNSQKTDSSNQTSFSELLKNS ISSLNESQVASDNMTNALAAGKDVNLDEVMIAAQKASISLTAATEFRNKAVEAYQEIM RMQM*" gene 1692130..1692450 /gene="fliE" /locus_tag="BSU_16200" /old_locus_tag="BSU16200" downshifts complement(1692445) /Source="Nicolas_upshifts" /id="D895" /incds=0 /nref=1 /ntot=83 /MaxReadThrough="1.38909" /MaxDrop="2.66249" /score="0.0645368779" /energy="-7.4" /TU="NA" /idTUdmin="U1325" /TUdmin=2684 /isTUend="FALSE" CDS 1692496..1694106 /gene="fliF" /locus_tag="BSU_16210" /old_locus_tag="BSU16210" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 1551848, 1905667, 2544561, 9161424, 11133968, 22670715, 24970213, 28089452; Product type s: structure" /codon_start=1 /transl_table=11 /product="flagellar basal-body M-ring protein" /protein_id="NP_389503.1" /db_xref="EnsemblGenomes-Gn:BSU16210" /db_xref="EnsemblGenomes-Tr:CAB13494" /db_xref="GOA:P23447" /db_xref="InterPro:IPR000067" /db_xref="InterPro:IPR006182" /db_xref="InterPro:IPR013556" /db_xref="InterPro:IPR021157" /db_xref="SubtiList:BG10240" /db_xref="UniProtKB/Swiss-Prot:P23447" /translation="MNRTLMQMKNKTSEFWKNRSKLQKILMVSALAAIIIIGIIISVF ASNSKMAPLYKDLSAEEAGQIKEELDAKKVPNELSNGGTVISVPEDQVDSLKVQMAAE GLPKTGSIDYSFFGQNAGFGLTDNEFDMVKVKATQTELSNLINEMDGIKNSKVMINLP KDAVFVGEEQSAASASIVLQIQPGYTLDQSQINGLYHLVSKSVPNLKEDNIVIMDQNS TYYDKSDSDAGSYADSYSSQQGIKSQVEKDIQKHVQSLLGTMMGQDKVVVSVTADIDF TKENRTEDIVEPVDKENMEGIAVSAEKVSETYQGDGAANGGTAGTGEEDVTNYKADGE NTESGNYEKNSNKINYEVNRIHKEIAESPYKVRDLGIQVMVEPPDAKNTASLSTERQD DIQKILSTVVRTSLDKDETQNQNLSDADINNKIVVSVQPFDGKVNLDTNTEESSGIPL WAYIVGGVLIAAIIVLIIMLIRKKRAQEDEFEEYEYEVPQEPINLPDINEEENETAES VRRKQLEKMAKDKPEDFAKLLRSWLAED*" gene 1692496..1694106 /gene="fliF" /locus_tag="BSU_16210" /old_locus_tag="BSU16210" CDS 1694119..1695135 /gene="fliG" /locus_tag="BSU_16220" /old_locus_tag="BSU16220" /function="16.5: Explore" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 1551848, 1905667, 2544561, 9161424, 10440379, 11133968, 28089452; Product type s : structure" /codon_start=1 /transl_table=11 /product="flagellar motor switching and energizing component" /protein_id="NP_389504.1" /db_xref="EnsemblGenomes-Gn:BSU16220" /db_xref="EnsemblGenomes-Tr:CAB13495" /db_xref="GOA:P23448" /db_xref="InterPro:IPR000090" /db_xref="InterPro:IPR011002" /db_xref="InterPro:IPR023087" /db_xref="InterPro:IPR028263" /db_xref="InterPro:IPR032779" /db_xref="SubtiList:BG10241" /db_xref="UniProtKB/Swiss-Prot:P23448" /translation="MARRDQDKLTGKQKAAILMISLGLDVSASVYKHLTDEEIERLTL EISGVRSVDHQKKDEIIEEFHNIAIAQDYISQGGLSYARQVLEKALGEDKAENILNRL TSSLQVKPFDFARKAEPEQILNFIQQEHPQTMALILSYLDPVQAGQILSELNPEVQAE VARRIAVMDRTSPEIINEVERILEQKLSSAFTQDYTQTGGIEAVVEVLNGVDRGTEKT ILDSLEIQDPDLAEEIKKRMFVFEDIVTLDNRAIQRVIRDVENDDLLLSLKVASEEVK EIVFNNMSQRMVETFKEEMEFMGPVRLKDVEEAQSRIVSIVRKLEEAGEIVIARGGGD DIIV*" gene 1694119..1695135 /gene="fliG" /locus_tag="BSU_16220" /old_locus_tag="BSU16220" S_feature 1695136..1695253 /Source="Nicolas_S_feature" /locus_tag="new_1695136_1695253" /HighExp="Lbstat, C90, M0t90, M40t90, Lbtran, C30, LPhT, GM 90, M40t45, GM-0.2" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigD, SigA" /TUshortPSig="0.998, 1, 0.998" /TUlongSig="SigA, SigA, SigA, SigD, SigA, SigA" /TUlongPSig="0.994, 1, 0.999, 1, 1, 1" /label="S585" promotor_no_box complement(1695199..1695299) /Source="Nicolas_upshift_promotors" /id="U1325" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.937062937062937" /psig="0.00999000999001" /xcortree=81 /SigmaFactorBS="ttgcctgctcagaaatccggtcagcttcctctttcactcggg ccataagcgcctccgggttctcttcagcctgcaaaaggtgagaatgatcaatacgcac c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_no_box" upshifts complement(1695239) /Source="Nicolas_upshifts" /id="U1325" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.937062937062937" /psig="0.00999000999001" /xcortree=81 /SigmaFactorBS="ttgcctgctcagaaatccggtcagcttcctctttcactcggg ccataagcgcctccgggttctcttcagcctgcaaaaggtgagaatgatcaatacgcac c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" CDS 1695254..1695880 /gene="fliH" /locus_tag="BSU_16230" /old_locus_tag="BSU16230" /function="16.6: Maintain" /function="16.5: Explore" /function="16.13: Shape" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 1828465, 12217691, 16522800, 17002279, 26916245; Product type f: factor" /codon_start=1 /transl_table=11 /product="flagellar export apparatus subunit of cytoplasmic ATPase" /protein_id="NP_389505.2" /db_xref="EnsemblGenomes-Gn:BSU16230" /db_xref="EnsemblGenomes-Tr:CAB13496" /db_xref="GOA:P23449" /db_xref="InterPro:IPR018035" /db_xref="InterPro:IPR022524" /db_xref="SubtiList:BG10242" /db_xref="UniProtKB/Swiss-Prot:P23449" /translation="MARVKEEADRISEQANSHIENIRRQIEQEKNDWAAEKQKLIEEA KAEGFEQGVALGKAEAMKQYAELIGQANSITEMSRKAVEDKLEDANEEIVELAVALAK KVWQQKSDDKEAFLLLVQQVINEVKEYDDISIYVDPYYYETIFQQKDEIQQLLYKECR LGIYADEKAQKGTCYIETPFGRVDASVDTQLMQLKDKLLTALEAGAAE*" gene 1695254..1695880 /gene="fliH" /locus_tag="BSU_16230" /old_locus_tag="BSU16230" CDS 1695877..1697193 /gene="fliI" /locus_tag="BSU_16240" /old_locus_tag="BSU16240" /EC_number="3.6.3.14" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 12787361, 16113269, 16780875, 17002279, 26916245; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="flagellar-specific ATPase subunit of export apparatus" /protein_id="NP_389506.2" /db_xref="EnsemblGenomes-Gn:BSU16240" /db_xref="EnsemblGenomes-Tr:CAB13497" /db_xref="GOA:P23445" /db_xref="InterPro:IPR000194" /db_xref="InterPro:IPR000225" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR004100" /db_xref="InterPro:IPR005714" /db_xref="InterPro:IPR020003" /db_xref="InterPro:IPR022425" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR032463" /db_xref="SubtiList:BG10243" /db_xref="UniProtKB/Swiss-Prot:P23445" /translation="MKTQSLIDCIEMTDSYKRYGKVKRVIGLMIESKGPASSIGDLCL IYAKGQSGKVIKAEVVGFQEENILLMPYLEAASIAPGSIVEATGESLRVKVGTGLIGQ VIDAFGEPLDGKLLPKGLSPVSTEQSPPNPMKRPPIREKMGVGVRSIDSLLTVGKGQR IGIFAGSGVGKSTLMGMIAKQTEADLNVIALVGERGREVREFIEKDLGKEGLKRSIVV VATSDQPALMRLKAAYTATAIAEYFRDKGQNVMFMMDSVTRVAMAQREIGLAAGEPPT TKGYTPSVFAILPRLLERTGANEHGTITAFYTVLVDGDDMNEPIADTVRGILDGHIVL DRALANKGQFPAVNVLKSISRVMSNISTKQHLDAANKFRELLSTYQNSEDLINIGAYK RGSSREIDEAIQFYPQLIQFLKQGTDEPALLEESIAALTSLTGNEE*" gene 1695877..1697193 /gene="fliI" /locus_tag="BSU_16240" /old_locus_tag="BSU16240" CDS 1697196..1697639 /gene="fliJ" /locus_tag="BSU_16250" /old_locus_tag="BSU16250" /function="16.13: Shape" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 17088562, 26916245, 26984495, 27647891; Product type f: factor" /codon_start=1 /transl_table=11 /product="flagellar synthesis rod subunit of export ATPase" /protein_id="NP_389507.1" /db_xref="EnsemblGenomes-Gn:BSU16250" /db_xref="EnsemblGenomes-Tr:CAB13498" /db_xref="GOA:P20487" /db_xref="InterPro:IPR012823" /db_xref="SubtiList:BG10245" /db_xref="UniProtKB/Swiss-Prot:P20487" /translation="MAYQFRFQKLLELKENEKDQSLSEYQQSVSEFENVAEKLYENMS KKELLEQNKEKKLKSGMSVQEMRHYQQFVSNLDNTIYHYQKLVIMKRNQMNQKQEILT EKNIEVKKFEKMREKQFKMFALEDKAAEMKEMDDISIKQFMIQGH*" gene 1697196..1697639 /gene="fliJ" /locus_tag="BSU_16250" /old_locus_tag="BSU16250" CDS 1697651..1698265 /gene="ylxF" /locus_tag="BSU_16260" /old_locus_tag="BSU16260" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 17586671, 22307758; Product type s: structure" /codon_start=1 /transl_table=11 /product="putative kinesin-like protein" /protein_id="NP_389508.2" /db_xref="EnsemblGenomes-Gn:BSU16260" /db_xref="EnsemblGenomes-Tr:CAB13499" /db_xref="GOA:P23454" /db_xref="InterPro:IPR006668" /db_xref="InterPro:IPR011002" /db_xref="SubtiList:BG10246" /db_xref="UniProtKB/Swiss-Prot:P23454" /translation="MSGKKKESGKFRSVLLIIILPLMFLLIAGGIVLWAAGINVLKPI QDAAAKTPVLKELVPETENKKGAASSKDSSNTAALEKTIKDQKSEISILNKDLETSKS EIDRLNQKIRSLEKTAEDQKKSSEDHTEGSADSKASSENDKVISVYKSMDSGKAAKII AQLKEQEALKILNGLSKKQLADILAKMTPEQAATYTEKIAASQE*" gene 1697651..1698265 /gene="ylxF" /locus_tag="BSU_16260" /old_locus_tag="BSU16260" CDS 1698278..1699741 /gene="fliK" /locus_tag="BSU_16270" /old_locus_tag="BSU16270" /function="16.5: Explore" /function="16.13: Shape" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 16630628, 16949608, 28557186; Product type f: factor" /codon_start=1 /transl_table=11 /product="flagellar hook-length control protein (ruler)" /protein_id="NP_389509.2" /db_xref="EnsemblGenomes-Gn:BSU16270" /db_xref="EnsemblGenomes-Tr:CAB13500" /db_xref="GOA:P23451" /db_xref="InterPro:IPR001635" /db_xref="InterPro:IPR021136" /db_xref="SubtiList:BG10247" /db_xref="UniProtKB/Swiss-Prot:P23451" /translation="MKLLELAGPLLQTTTGSAAKNMKSSQGVFQNWLMSEAGLKELSE QGKGTPNSEDQLLADALKKIGEWLNASPEDQDKQNADLLQTLSKLTGKQLDANALQML QNLLQAVESKMSGGTDQLLTETEKIFSEAKTALSANDSASDINGALKSDKEQSNQENE VSEPAKELIYIQMFISQLVEGNKLTDLGNGNEAHAIYQNGDQFLSALEKKGVSQQLIQ DLKQQIFTKAESSSKLYSMTASELKSFQSLMDQMSMLPQKGTKEWSLAESQLKAFLLS KSSESSQDFGKSVLTPLSQSSSSKNASDVSGSIQPVDSKSGLQMLFSGYRGIGGVQTL DLQQMSSDIPNAETKTVADQVINAWKQMKYTPFGRSTGSFTIRLNPEHLGFVTIKLTN ENGMFQSKIIASSQSAKELLEQHLPQLKQSLPNMAVQIDRFTLPVQSGDQPIYGQLAD EQKQQQEGQRQQRQKKQSNDFGDLLDEVSMVEMEEEE*" gene 1698278..1699741 /gene="fliK" /locus_tag="BSU_16270" /old_locus_tag="BSU16270" CDS 1699738..1700160 /gene="flgD" /locus_tag="BSU_16280" /old_locus_tag="BSU16280" /function="16.13: Shape" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 8157595, 14563871, 24748615; Product type f: factor" /codon_start=1 /transl_table=11 /product="flagellar hook capping protein" /protein_id="NP_389510.1" /db_xref="EnsemblGenomes-Gn:BSU16280" /db_xref="EnsemblGenomes-Tr:CAB13501" /db_xref="GOA:P23455" /db_xref="InterPro:IPR005648" /db_xref="SubtiList:BG10248" /db_xref="UniProtKB/Swiss-Prot:P23455" /translation="MTSISSEYKLPEKTNTVSTNNSSLGKDEFLKILMTQVQNQDPLN PIDDKEFISQMATFSSLEQMMNLNTTMTQFVENQDPFTTYVDWMGKEVSWTDGKSATD KTGTVSSVKHFKGNYYLVLDDGTEISPANVMSVGQSSK*" gene 1699738..1700160 /gene="flgD" /locus_tag="BSU_16280" /old_locus_tag="BSU16280" CDS 1700182..1700976 /gene="flgE" /locus_tag="BSU_16290" /old_locus_tag="BSU16290" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 15502333, 15510139, 27759043, 28120828, 28429800; Product type f: factor" /codon_start=1 /transl_table=11 /product="flagellar hook protein" /protein_id="NP_389511.2" /db_xref="EnsemblGenomes-Gn:BSU16290" /db_xref="EnsemblGenomes-Tr:CAB13502" /db_xref="GOA:P23446" /db_xref="InterPro:IPR001444" /db_xref="InterPro:IPR010930" /db_xref="InterPro:IPR012836" /db_xref="InterPro:IPR019776" /db_xref="InterPro:IPR020013" /db_xref="SubtiList:BG10249" /db_xref="UniProtKB/Swiss-Prot:P23446" /translation="MLRSLYSGISGMKNFQTKLDVIGNNIANVNTVGFKKSRVTFKDM VSQTIAGGSAAGATIGGTNSKQIGLGSSSGTIDTIHSTSATQSTGRTLDLAIDGDGYF RIDTGDGTAYTRAGNFYLDNTGTLVTGDGYHVLNMNGGTIKIPTDAQSFSIGSDGKVS IVDAEGKTQDGGQIGIVTFANSDGLDKIGSNLYRESLNSGTASAANQPGDGGTGALKS GFLEMSNVDLTDEFTEMIVAQRGFQSNSKIITTSDEILQELVNLKR*" gene 1700182..1700976 /gene="flgE" /locus_tag="BSU_16290" /old_locus_tag="BSU16290" CDS 1701016..1701231 /gene="swrD" /locus_tag="BSU_16299" /old_locus_tag="BSU16299" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:9168127, 29061663" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9168127, 29061663; Product type f: factor" /codon_start=1 /transl_table=11 /product="flagellar power transducer required for swarming" /protein_id="YP_003097728.1" /db_xref="EnsemblGenomes-Gn:BSU16299" /db_xref="EnsemblGenomes-Tr:CAX52619" /db_xref="InterPro:IPR009384" /db_xref="UniProtKB/Swiss-Prot:C0H412" /translation="MIKVTRLNGQPFTLNALFIEQIECFPDTTITLSNGKKFVVKEDE EAVLEKIAAFYRKIQIFAMDQGIEEPE*" gene 1701016..1701231 /gene="swrD" /locus_tag="BSU_16299" /old_locus_tag="BSU16299" CDS 1701228..1701650 /gene="fliL" /locus_tag="BSU_16300" /old_locus_tag="BSU16300" /function="16.5: Explore" /function="16.12: Sense" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 10439416, 12787361, 16166542, 23264580, 25714720, 28717192; Product type f : factor" /codon_start=1 /transl_table=11 /product="flagellar basal-body (stator) associated protein" /protein_id="NP_389512.1" /db_xref="EnsemblGenomes-Gn:BSU16300" /db_xref="EnsemblGenomes-Tr:CAB13503" /db_xref="GOA:P23452" /db_xref="InterPro:IPR005503" /db_xref="SubtiList:BG10250" /db_xref="UniProtKB/Swiss-Prot:P23452" /translation="MKKKLMIILLIILIVIGALGAAAYFVLGGKSEKSEAKKSIDEIV ASSVDVEEITTNLKSDNIIRLAIKLETDSDKSKEELEKRDFQVKDAVISLLADTNADQ IEGDKGKETFKKELKDKINSYLQEGKVEKVYITSFNLQ*" gene 1701228..1701650 /gene="fliL" /locus_tag="BSU_16300" /old_locus_tag="BSU16300" CDS 1701684..1702682 /gene="fliM" /locus_tag="BSU_16310" /old_locus_tag="BSU16310" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 7787061, 16547037, 16796690, 16882724, 17015643, 17050923, 22720735, 28625846; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="flagellar motor switching and energizing component" /protein_id="NP_389513.1" /db_xref="EnsemblGenomes-Gn:BSU16310" /db_xref="EnsemblGenomes-Tr:CAB13504" /db_xref="GOA:P23453" /db_xref="InterPro:IPR001543" /db_xref="InterPro:IPR001689" /db_xref="InterPro:IPR028976" /db_xref="InterPro:IPR036429" /db_xref="SubtiList:BG10251" /db_xref="UniProtKB/Swiss-Prot:P23453" /translation="MSGEVLSQNEIDALLSAISTGEMDAEELKKEEKEKKVKVYDFKR ALRFSKDQIRSLTRIHDNFARLLTTHFSAQLRTYIHISVSSVDQVPYEEFIRSIPNMT ILNLFDVHPMEGRIMMEVNPTIAYTMMDRVMGGIGISHNKVDSLTEIETKIISNLFEN ALGNYKEAWQSIADIEPEMTEFEVNPQFVQMVSPNETVVVISLNTQIGEISGVINLCI PHIVLEPLIPKLSVHYWMQSDRNEPKPEETKSLEKRIMTAQIPVVAELGTSELTIEEF LSLEVGDCITLDKSVTDPLTVLVGDKPKFLGQAGRVNRKQAVQILDHDIRGEQDGE*" gene 1701684..1702682 /gene="fliM" /locus_tag="BSU_16310" /old_locus_tag="BSU16310" CDS 1702672..1703808 /gene="fliY" /locus_tag="BSU_16320" /old_locus_tag="BSU16320" /function="16.5: Explore" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:12920116, 16547037, 16796690, 16882724, 17015643, 17050923, 23226535, 23532838, 26195616" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12920116, 16547037, 16796690, 16882724, 17015643, 17050923, 23226535, 23532838, 26195616; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="flagellar motor switching and energizing phosphatase" /protein_id="NP_389514.1" /db_xref="EnsemblGenomes-Gn:BSU16320" /db_xref="EnsemblGenomes-Tr:CAB13505" /db_xref="GOA:P24073" /db_xref="InterPro:IPR001172" /db_xref="InterPro:IPR001543" /db_xref="InterPro:IPR007597" /db_xref="InterPro:IPR012826" /db_xref="InterPro:IPR028976" /db_xref="InterPro:IPR036429" /db_xref="SubtiList:BG10252" /db_xref="UniProtKB/Swiss-Prot:P24073" /translation="MENNRLSQDEIDALLNGTGSTLDEPEIPEVDDLSEMERDAIGEI GNISFGSSATALSTLLNQKVDITTPSVTVIPRSKISDAFPEPYVAIEVNYTEGFSGSN LLVVEQSDAAIIADLMIGGDGKGADPSLGEIHLSAVQEAMNQMMGSAATSMSTVFSKK IDISPPRVELLDVTEEKGTDRIPDDEMLVKVSFNLKVGELIDSSIMQLYPLTFAKDLI SSLMNSESAEEEETVQPEVTYEQPKEPVTPEPRIEPKQQQQPPKRQGTAKKAAPVQVS PVEFSAFDPNEAVQAPIHNLDMLLDIPLSITVELGRTKRSVKEILELSAGSIIELDKL AGEPVDILVNQRIVAKGEVVVIEENFGVRVTDILSQAERINNLK*" gene 1702672..1703808 /gene="fliY" /locus_tag="BSU_16320" /old_locus_tag="BSU16320" CDS 1703834..1704196 /gene="cheY" /locus_tag="BSU_16330" /old_locus_tag="BSU16330" /function="16.3: Control" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:10196193, 12864845, 12920116, 14749334, 23226535, 28542702" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10196193, 12864845, 12920116, 14749334, 23226535, 28542702; Product type r : regulator" /codon_start=1 /transl_table=11 /product="regulator of chemotaxis and motility" /protein_id="NP_389515.1" /db_xref="EnsemblGenomes-Gn:BSU16330" /db_xref="EnsemblGenomes-Tr:CAB13506" /db_xref="GOA:P24072" /db_xref="InterPro:IPR001789" /db_xref="InterPro:IPR011006" /db_xref="SubtiList:BG10258" /db_xref="UniProtKB/Swiss-Prot:P24072" /translation="MAHRILIVDDAAFMRMMIKDILVKNGFEVVAEAENGAQAVEKYK EHSPDLVTMDITMPEMDGITALKEIKQIDAQARIIMCSAMGQQSMVIDAIQAGAKDFI VKPFQADRVLEAINKTLN*" gene 1703834..1704196 /gene="cheY" /locus_tag="BSU_16330" /old_locus_tag="BSU16330" CDS 1704211..1704870 /gene="fliZ" /locus_tag="BSU_16340" /old_locus_tag="BSU16340" /function="16.3: Control" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 10791024, 1597417, 16513753, 24204316; Product type r: regulator" /codon_start=1 /transl_table=11 /product="flagellar regulatory protein" /protein_id="NP_389516.1" /db_xref="EnsemblGenomes-Gn:BSU16340" /db_xref="EnsemblGenomes-Tr:CAB13507" /db_xref="GOA:P35536" /db_xref="InterPro:IPR022781" /db_xref="SubtiList:BG10259" /db_xref="UniProtKB/Swiss-Prot:P35536" /translation="MKKSQYFIVFICFFVLFSVHPIAAAAADSDNSTVNEWFQKKDEK TADQSEQKKEKTTKTADETEGAAAPSVSAFDFVKMIFALLFVIVLIYGLVKLMNKRNR LLKPFQYVENIGGTSVGQNRSIQLIKVGKSVLVVGVGETIQLLKEIEDEKEIEVILSQ HEEAMSSKIEWQKFVKPLKSSEHQPQQKLPSFSKALKEQLEELKQNRSEGKKKGPRHH E*" gene 1704211..1704870 /gene="fliZ" /locus_tag="BSU_16340" /old_locus_tag="BSU16340" CDS 1704863..1705528 /gene="fliP" /locus_tag="BSU_16350" /old_locus_tag="BSU16350" /function="16.3: Control" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 15516571, 15849754, 16850406, 22720735, 26244495, 27855178, 28559296; Product type t: transporter" /codon_start=1 /transl_table=11 /product="component of the flagellar export machinery" /protein_id="NP_389517.1" /db_xref="EnsemblGenomes-Gn:BSU16350" /db_xref="EnsemblGenomes-Tr:CAB13508" /db_xref="GOA:P35528" /db_xref="InterPro:IPR005837" /db_xref="InterPro:IPR005838" /db_xref="SubtiList:BG10260" /db_xref="UniProtKB/Swiss-Prot:P35528" /translation="MNEFINIFSSSDPENVSSTVKLLLLLTVFSVAPGILILMTCFTR IVIVLSFVRTSLATQSMPPNQVLIGLALFLTFFIMAPTFSEINKEALTPLMDNKISLD EAYTKAEEPIKEFMSKHTRQKDLALFMNYAKMDKPESLKDIPLTTMVPAFAISELKTA FQIGFMIFIPFLIIDMVVASVLMSMGMMMLPPVMISLPFKILLFVLVDGWYLIVKSLL QSF*" gene 1704863..1705528 /gene="fliP" /locus_tag="BSU_16350" /old_locus_tag="BSU16350" CDS 1705543..1705812 /gene="fliQ" /locus_tag="BSU_16360" /old_locus_tag="BSU16360" /function="16.5: Explore" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 10234819, 15516571, 27855178; Product type t: transporter" /codon_start=1 /transl_table=11 /product="component of the flagellar export machinery" /protein_id="NP_389518.1" /db_xref="EnsemblGenomes-Gn:BSU16360" /db_xref="EnsemblGenomes-Tr:CAB13509" /db_xref="GOA:P35535" /db_xref="InterPro:IPR002191" /db_xref="InterPro:IPR006305" /db_xref="SubtiList:BG10261" /db_xref="UniProtKB/Swiss-Prot:P35535" /translation="MSSEFVISMAEKAVYVTLMISGPLLAIALLVGLIVSIFQATTQI QEQTLAFIPKIVAVLLALIFFGPWMLSTILSFTTELFSNLNRFAG*" gene 1705543..1705812 /gene="fliQ" /locus_tag="BSU_16360" /old_locus_tag="BSU16360" CDS 1705820..1706599 /gene="fliR" /locus_tag="BSU_16370" /old_locus_tag="BSU16370" /function="16.5: Explore" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 15060055, 15516571, 15849754, 16850406, 28771474; Product type t : transporter" /codon_start=1 /transl_table=11 /product="component of the flagellar export machinery" /protein_id="NP_389519.2" /db_xref="EnsemblGenomes-Gn:BSU16370" /db_xref="EnsemblGenomes-Tr:CAB13510" /db_xref="GOA:P35537" /db_xref="InterPro:IPR002010" /db_xref="InterPro:IPR006303" /db_xref="SubtiList:BG10262" /db_xref="UniProtKB/Swiss-Prot:P35537" /translation="MNSIIDLFPAFLLVFIRISAFFVTIPLFGHRNVPAVHRIGFAFF LAVICFSTIDKPPSLEIDEHYMLLAFKEALVGLCLGLIAYMMIAAVQIAGSFIDFQMG FSIANVIDPQTGAQSPLIGQFIYTMALLFMLSVNAHHLLLDGIYYSFQYISVDQAFPN FGDEKFAYFIAKSFNAMFIIAFQMSAPVVASLFLVDLALGIVARTVPQLNVFVVGLPL KIAVSFIMLIVCMSVIFVVVRNVFSLTIETMRNLLALVGVS*" gene 1705820..1706599 /gene="fliR" /locus_tag="BSU_16370" /old_locus_tag="BSU16370" CDS 1706599..1707681 /gene="flhB" /locus_tag="BSU_16380" /old_locus_tag="BSU16380" /function="16.1: Circulate" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 10234819, 16949608, 17050924, 17067800, 28557186, 28771466; Product type t : transporter" /codon_start=1 /transl_table=11 /product="component of the flagellar export machinery" /protein_id="NP_389520.1" /db_xref="EnsemblGenomes-Gn:BSU16380" /db_xref="EnsemblGenomes-Tr:CAB13511" /db_xref="GOA:P35538" /db_xref="InterPro:IPR006135" /db_xref="InterPro:IPR006136" /db_xref="InterPro:IPR029025" /db_xref="SubtiList:BG10543" /db_xref="UniProtKB/Swiss-Prot:P35538" /translation="MKLRVDLQFFAGEKTEKATPKKRKDTRKKGQVAKSSDVNTAVSL LVIFLSLIAIGPYMRDRLLSFIETFYTESLTMKLSESNVHTLFVSLLKDMGMILAPIL LVALVAGVVSNYMQVGFLFSAEVIQPKLEKLDPIKGFKRIYSMRAIVELIKSILKIVV VGFAAFAVLWLHYGEILRLPLLTPEEALSFVSKLTLWMGLSGAGALLILAGLDYLYQR FDYEKNIKMSKQDIKDEYKKSEGDPIIKSKIKQRQREMAMRRMMQEVPKADVIITNPT HYAIALKYDEEKMDAPYIVAKGVDHLALKIRKIAKEHDVMMVENRPLARALYDQVEID QAVPEEFFKVLAEILAYVYKTKQKVY*" gene 1706599..1707681 /gene="flhB" /locus_tag="BSU_16380" /old_locus_tag="BSU16380" CDS 1707714..1709747 /gene="flhA" /locus_tag="BSU_16390" /old_locus_tag="BSU16390" /function="16.1: Circulate" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:10234819, 15516571, 20534509, 28771466" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10234819, 15516571, 20534509, 28771466; Product type f: factor" /codon_start=1 /transl_table=11 /product="component of the flagellar export machinery" /protein_id="NP_389521.2" /db_xref="EnsemblGenomes-Gn:BSU16390" /db_xref="EnsemblGenomes-Tr:CAB13512" /db_xref="GOA:P35620" /db_xref="InterPro:IPR001712" /db_xref="InterPro:IPR006301" /db_xref="InterPro:IPR025505" /db_xref="PDB:3MIX" /db_xref="SubtiList:BG10542" /db_xref="UniProtKB/Swiss-Prot:P35620" /translation="MSTRDLSVLISVVLIVAMLVIPFPPWLLSILIIINISLALIVLL TTMNMQEALQFSIFPSLLLLLTLFRLGLNVSTTRSILSHGEGGKVVETFGNFVVGGNV LVGLVVFIILIIIQFIVITKGAERVSEVAARFTLDAMPGKQMSIDADLNAGMITEQEA KHRREKVAREADFYGAMDGASKFVKGDAIAGIIIVMINIIFGIVIGMLQQGMSIQEAA SHFTMLTVGDGIVSQIPALLISTATGIVVTRAASEGNLGHDITGQLFAYPKLLYVAAA TIMLLGIFTPIGILLTGPLAGLLAFGAYTLSKSGKEKEEVDEILEEEAEVDELKSPES VVQLLHIDPIEFEFGYGLIPLADANQGGDLLDRIVMIRRQLALELGLVIPVVRIRDNI ALQPNEYRLKIKGNEVAKGELLLDHYLAMSPTPEDDLIEGIETVEPSFGLPAKWISEA VKDEADMLGYTVVDPASVVSTHITEKIKQHAHELIGRQETKQLIDHLKESYPVLVEEV TPNPLSVGDIQKVLAKLLKEKVSIRNLVTIFETLADYGKLTTDSDLLTEYTRQALAKQ ITAQFAKENEVLKVVTCSGRVEKAIADGVQQTEHGNYLSLEPDISESIVRSVAKEAEQ LSLRQETAILLCSPPVRMYVKQLLERYFPDLPVLSYNELEANVEVQSIGVVDI*" gene 1707714..1709747 /gene="flhA" /locus_tag="BSU_16390" /old_locus_tag="BSU16390" CDS 1709747..1710847 /gene="flhF" /locus_tag="BSU_16400" /old_locus_tag="BSU16400" /function="16.5: Explore" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1c: Function from experimental evidences in the studied genus; PubMedId: 1447978, 15317803, 16980502, 17565194, 17699634, 26195616, 27807433; Product type t: transporter" /codon_start=1 /transl_table=11 /product="GTPase involved in the export of flagella and number regulation" /protein_id="NP_389522.1" /db_xref="EnsemblGenomes-Gn:BSU16400" /db_xref="EnsemblGenomes-Tr:CAB13513" /db_xref="GOA:Q01960" /db_xref="InterPro:IPR000897" /db_xref="InterPro:IPR020006" /db_xref="InterPro:IPR027417" /db_xref="PDB:2PX0" /db_xref="PDB:2PX3" /db_xref="PDB:3SYN" /db_xref="SubtiList:BG10544" /db_xref="UniProtKB/Swiss-Prot:Q01960" /translation="MKIKKFTAASMQEAALLIRKELGNEAVILNSKKIKKRKWFGLVN KPAVEVIAVLDQDFLEKKTPQKAAEPKQTLKTPVSSPKIEERTYPPQIPAQQELGDFS AYQSVLPEPLRKAEKLLQETGIKESTKTNTLKKLLRFSVEAGGLTEENVVGKLQEILC DMLPSADKWQEPIHSKYIVLFGSTGAGKTTTLAKLAAISMLEKHKKIAFITTDTYRIA AVEQLKTYAELLQAPLEVCYTKEEFQQAKELFSEYDHVFVDTAGRNFKDPQYIDELKE TIPFESSIQSFLVLSATAKYEDMKHIVKRFSSVPVNQYIFTKIDETTSLGSVFNILAE SKIGVGFMTNGQNVPEDIQTVSPLGFVRMLCR*" gene 1709747..1710847 /gene="flhF" /locus_tag="BSU_16400" /old_locus_tag="BSU16400" promotor_-10 complement(1710724..1710743) /Source="Nicolas_upshift_promotors" /id="U1326" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.993006993006993" /psig="0.993006993006993" /xcortree=1367 /SigmaFactorBS="gcacattctggccgttagtcataaaCCCGACACCTatttttg attctgCCAGTATATTAAATACAGAAcctaaggaagtcgtttcatctattttcgtaaa a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1710731) /Source="Nicolas_upshifts" /id="U1326" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.993006993006993" /psig="0.993006993006993" /xcortree=1367 /SigmaFactorBS="gcacattctggccgttagtcataaaCCCGACACCTatttttg attctgCCAGTATATTAAATACAGAAcctaaggaagtcgtttcatctattttcgtaaa a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(1710757..1710766) /Source="Nicolas_upshift_promotors" /id="U1326" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.993006993006993" /psig="0.993006993006993" /xcortree=1367 /SigmaFactorBS="gcacattctggccgttagtcataaaCCCGACACCTatttttg attctgCCAGTATATTAAATACAGAAcctaaggaagtcgtttcatctattttcgtaaa a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" CDS 1710838..1711734 /gene="flhG" /locus_tag="BSU_16410" /old_locus_tag="BSU16410" /function="16.5: Explore" /function="16.6: Maintain" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:15361076, 25733861, 26411371" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15361076, 25733861, 26411371; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="ATPase affecting flagellar basal body localisation and number" /protein_id="NP_389523.1" /db_xref="EnsemblGenomes-Gn:BSU16410" /db_xref="EnsemblGenomes-Tr:CAB13514" /db_xref="GOA:P40742" /db_xref="InterPro:IPR025501" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR033756" /db_xref="InterPro:IPR033875" /db_xref="PDB:3SYN" /db_xref="SubtiList:BG10254" /db_xref="UniProtKB/Swiss-Prot:P40742" /translation="MQMNRYDQAATLRAKMEKRERVLPMVYSQKAKTLAVISGKGGVG KSNITLNMALALQDKGKKVLLIDLDIGMGNIDILIGNSSSATIIDVLTDRKPLLQSLS VGPKGLRYISGGTGLDVMFQLDQRKWTFFANELSHALSQFDYVLFDMGAGLSKDQLPF ILSAEDILIITTPEPTAIMDAYSAVKHLVLTENKLSMKVAVNRCRDQKEGLDAFARLS RTIHMFLDVQVQFAGSVSDDVIVSKAVVEQVPFFIKSPQAKASRSVRILADALFEREE TRHKEDKQTFIEKLSSFLMRRA*" gene 1710838..1711734 /gene="flhG" /locus_tag="BSU_16410" /old_locus_tag="BSU16410" CDS 1711736..1712809 /gene="cheB" /locus_tag="BSU_16420" /old_locus_tag="BSU16420" /EC_number="3.1.1.61" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:1738311, 10632876, 12123464, 21515776" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1738311, 10632876, 12123464, 21515776; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="methyl-accepting chemotaxis proteins (MCP)-glutamate methylesterase" /protein_id="NP_389524.2" /db_xref="EnsemblGenomes-Gn:BSU16420" /db_xref="EnsemblGenomes-Tr:CAB13515" /db_xref="GOA:Q05522" /db_xref="InterPro:IPR000673" /db_xref="InterPro:IPR001789" /db_xref="InterPro:IPR008248" /db_xref="InterPro:IPR011006" /db_xref="InterPro:IPR035909" /db_xref="SubtiList:BG10255" /db_xref="UniProtKB/Swiss-Prot:Q05522" /translation="MIRVLVVDDSAFMRKMISDFLTEEKQIEVIGTARNGEEALKKIE LLKPDVITLDVEMPVMNGTDTLRKIIEIYNLPVIMVSSQTEKGKECTINCLEIGAFDF ITKPSGSISLDLYKIKEQLVERVVAAGLSGKRKRPVSQTVRPEPIVRAVVKPELSKPK PGTGRQIVCIGTSTGGPRALQKVIPKLPKDLNAPVVVVQHMPEGFTASLADRLNHLSD IQVKEAKDGEAALNGCVYIAPGGKNISVIKNSEGLQVVLDNHDTPSRHKPSADYLFRS VGKLTDYEKVAVIMTGMGSDGTAGLKDMLTAGNVKAIAESEESCVVYGMPKAAVKAGL IHEIKHVEDIAASITSCVKKERV*" gene 1711736..1712809 /gene="cheB" /locus_tag="BSU_16420" /old_locus_tag="BSU16420" CDS 1712815..1714833 /gene="cheA" /locus_tag="BSU_16430" /old_locus_tag="BSU16430" /EC_number="2.7.3.-" /function="16.3: Control" /function="16.12: Sense" /experiment="publication(s) with functional evidences, PMID:12094812, 12864845, 12920116, 15451661, 16045621, 21515776, 22355139" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12094812, 12864845, 12920116, 15451661, 16045621, 21515776, 22355139; Product type rc: receptor" /codon_start=1 /transl_table=11 /product="chemotactic two-component sensor histidine kinase" /protein_id="NP_389525.2" /db_xref="EnsemblGenomes-Gn:BSU16430" /db_xref="EnsemblGenomes-Tr:CAB13516" /db_xref="GOA:P29072" /db_xref="InterPro:IPR002545" /db_xref="InterPro:IPR003594" /db_xref="InterPro:IPR004105" /db_xref="InterPro:IPR004358" /db_xref="InterPro:IPR005467" /db_xref="InterPro:IPR008207" /db_xref="InterPro:IPR010808" /db_xref="InterPro:IPR035891" /db_xref="InterPro:IPR036061" /db_xref="InterPro:IPR036097" /db_xref="InterPro:IPR036641" /db_xref="InterPro:IPR036890" /db_xref="InterPro:IPR037006" /db_xref="InterPro:IPR037052" /db_xref="SubtiList:BG10256" /db_xref="UniProtKB/Swiss-Prot:P29072" /translation="MDMNQYLDVFIDESKEHLQTCNEKLLLLEKDPTDLQLVHDIFRA AHTLKGMSATMGYTDLAHLTHLLENVLDAIRNGDMEVTSDWLDILFEALDHLETMVQS IIDGGDGKRDISEVSAKLDVNGAHAESAASAEPAEAQSSASDWEYDEFERTVIQEAEE QGFKRYEIKISLNENCMLKAVRVYMVFEKLNEVGEVAKTIPSAEVLETEDFGTDFQVC FLTHQSAEDIEQLINGVSEIEHVEVIQGAPLTSAEKPEESKQEDSPAAAVPAKQEKQK QPAKNDEQAKHSAGGSKTIRVNIDRLDSLMNLFEELVIDRGRLEQIAKELEHNELTET VERMTRISGDLQSIILNMRMVPVETVFNRFPRMIRQLQKELNKKIELSIIGAETELDR TVIDEIGDPLVHLIRNSIDHGIEAPETRLQKGKPESGKVVLKAYHSGNHVFIEVEDDG AGLNRKKILEKALERGVITEKEAETLEDNQIYELIFAPGFSTADQISDISGRGVGLDV VKNKLESLGGSVSVKSAEGQGSLFSIQLPLTLSIISVLLIKLEEETFAIPISSIIETA VIDRKDILQTHDREVIDFRGHIVPVVYLKEEFKIEDTRKDAEQLHIIVVKKGDKPTAF VVDSFIGQQEVVLKSLGDYLTNVFAISGATILGDGEVALIIDCNALII*" gene 1712815..1714833 /gene="cheA" /locus_tag="BSU_16430" /old_locus_tag="BSU16430" CDS 1714855..1715325 /gene="cheW" /locus_tag="BSU_16440" /old_locus_tag="BSU16440" /function="16.3: Control" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:12864845, 15451661, 1624415, 8169223, 8169224" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12864845, 15451661, 1624415, 8169223, 8169224; Product type r: regulator" /codon_start=1 /transl_table=11 /product="modulation of CheA activity in response to attractants (chemotaxis)" /protein_id="NP_389526.1" /db_xref="EnsemblGenomes-Gn:BSU16440" /db_xref="EnsemblGenomes-Tr:CAB13517" /db_xref="GOA:P39802" /db_xref="InterPro:IPR002545" /db_xref="InterPro:IPR036061" /db_xref="SubtiList:BG10692" /db_xref="UniProtKB/Swiss-Prot:P39802" /translation="MTAEIKTGEKMIVFMVNGKEYAISVTQVKSIEKWQKPTRVPGVE PYICGVINLRGVVTPVIDLRKRLNLPEYEITDETRIIIIAYRDIEVGWIVDEANDVIT VHESEIESAPEGVQKDTDVSIEQIVKQENRLLNIIDANAVLDKESSQSAVPDQA*" gene 1714855..1715325 /gene="cheW" /locus_tag="BSU_16440" /old_locus_tag="BSU16440" CDS 1715344..1715973 /gene="cheC" /locus_tag="BSU_16450" /old_locus_tag="BSU16450" /function="16.3: Control" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:12920116, 14749334, 14993307, 15546616, 16469702, 18990184, 22720735, 23226535" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12920116, 14749334, 14993307, 15546616, 16469702, 18990184, 22720735, 23226535; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="signal terminating phosphatase of CheR-mediated methylation of methyl-accepting chemotaxis proteins (MCPs)" /protein_id="NP_389527.1" /db_xref="EnsemblGenomes-Gn:BSU16450" /db_xref="EnsemblGenomes-Tr:CAB13518" /db_xref="GOA:P40403" /db_xref="InterPro:IPR007597" /db_xref="InterPro:IPR028976" /db_xref="SubtiList:BG10749" /db_xref="UniProtKB/Swiss-Prot:P40403" /translation="MSIFNGIKEEQMDILREVGNIGAGHSASAMAQLLNRKIDMEVPF AKLLSFDELVDFFGGADVPVASIFLRMEGDLTGSMFFIMPFFQAEQFIRELIGNPDFD IEDLGEDHMSSSALHELGNILAGSYLTALADLTKLQLYPSVPEVSLDMFGAVISEGLM ELSQVGEHAIVVDTSIFDQSHQQELKAHMFMLPDYDSFEKLFVALGASL*" gene 1715344..1715973 /gene="cheC" /locus_tag="BSU_16450" /old_locus_tag="BSU16450" CDS 1715970..1716470 /gene="cheD" /locus_tag="BSU_16460" /old_locus_tag="BSU16460" /function="16.3: Control" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:15546616, 16469702, 22720735, 23226535" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15546616, 16469702, 22720735, 23226535; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="sequence specific deamidase required for methylation of methyl-accepting chemotaxis proteins (MCPs) by CheR" /protein_id="NP_389528.1" /db_xref="EnsemblGenomes-Gn:BSU16460" /db_xref="EnsemblGenomes-Tr:CAB13519" /db_xref="GOA:P40404" /db_xref="InterPro:IPR005659" /db_xref="InterPro:IPR011324" /db_xref="SubtiList:BG10750" /db_xref="UniProtKB/Swiss-Prot:P40404" /translation="MSTTEAVVIKVGIADVKIARFPDTIRTSGLGSCVGLVLYDKEKQ TAGLVHVMLPDSTLSKTAELNRAKYADTAVQTTIDMLIEAGCRKFALKAKLAGGSEMF KFKSTNDLMKIGPRNVLAIKEQLSLFNIPIISEDTGGSSGRTIEFEPKSCMLHIRTVK QGEKTI*" gene 1715970..1716470 /gene="cheD" /locus_tag="BSU_16460" /old_locus_tag="BSU16460" CDS 1716493..1717257 /gene="sigD" /locus_tag="BSU_16470" /old_locus_tag="BSU16470" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:2498284, 9648743, 9657996, 11751842, 15033535, 15066026, 15175317, 22329926, 22956758, 25288929, 26170408" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 2498284, 9648743, 9657996, 11751842, 15033535, 15066026, 15175317, 22329926, 22956758, 25288929, 26170408; Product type r : regulator" /codon_start=1 /transl_table=11 /product="RNA polymerase sigma-28 factor (sigma-D)" /protein_id="NP_389529.1" /db_xref="EnsemblGenomes-Gn:BSU16470" /db_xref="EnsemblGenomes-Tr:CAB13520" /db_xref="GOA:P10726" /db_xref="InterPro:IPR000943" /db_xref="InterPro:IPR007624" /db_xref="InterPro:IPR007627" /db_xref="InterPro:IPR007630" /db_xref="InterPro:IPR012845" /db_xref="InterPro:IPR013324" /db_xref="InterPro:IPR013325" /db_xref="InterPro:IPR014284" /db_xref="InterPro:IPR036388" /db_xref="SubtiList:BG10751" /db_xref="UniProtKB/Swiss-Prot:P10726" /translation="MQSLNYEDQVLWTRWKEWKDPKAGDDLMRRYMPLVTYHVGRISV GLPKSVHKDDLMSLGMLGLYDALEKFDPSRDLKFDTYASFRIRGAIIDGLRKEDWLPR TSREKTKKVEAAIEKLEQRYLRNVSPAEIAEELGMTVQDVVSTMNEGFFANLLSIDEK LHDQDDGENIQVMIRDDKNVPPEEKIMKDELIAQLAEKIHELSEKEQLVVSLFYKEEL TLTEIGQVLNLSTSRISQIHSKALFKLKNLLEKVIQ*" gene 1716493..1717257 /gene="sigD" /locus_tag="BSU_16470" /old_locus_tag="BSU16470" promotor_-35 1717267..1717273 /Source="Nicolas_upshift_promotors" /id="U1327" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.665334665334665" /psig="0.665334665334665" /xcortree=682 /SigmaFactorBS="aaaagtgatacaataatgaatttcaTGGTTAGcgagtgaaaa acatGTCAACACTATTatggcttttaagctttatgctccacggcgttcttctgtacgc t" /listShort="ylxL" /listLong="S586, rpsB, S587, tsf, S588, pyrH, frr, S589, uppS, cdsA, dxr, rseP, proS, S590, polC, S591, S592, S593, ylxS, nusA, ylxR, rplGA, infB, ylxP, rbfA, truB, ribC, S594, rpsO, S595, pnpA, S596, ylxY, mlpA" /label="promotor_-35" CDS 1717286..1717789 /gene="swrB" /locus_tag="BSU_16480" /old_locus_tag="BSU16480" /function="16.12: Sense" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:15066026, 15175317, 19202088, 21736639, 26244495" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15066026, 15175317, 19202088, 21736639, 26244495; Product type r: regulator" /codon_start=1 /transl_table=11 /product="coupling factor for flagellin transcription and translation" /protein_id="NP_389530.1" /db_xref="EnsemblGenomes-Gn:BSU16480" /db_xref="EnsemblGenomes-Tr:CAB13521" /db_xref="SubtiList:BG10752" /db_xref="UniProtKB/Swiss-Prot:P40405" /translation="MSTLLWLLSFMLHGVLLYAVIILYTRLAAVKETEKQQKQILEET ENTLAAFLLELKEENEKLIENKASSASQSDEESQKSGLQTSETYQERDPVQEAENLPE HIEGLITEVDRREELVNSEVQSFEDQVIELYEQGYSASQIAQKMKSGKTEIELFLKFR SKGVKDS*" gene 1717286..1717789 /gene="swrB" /locus_tag="BSU_16480" /old_locus_tag="BSU16480" promotor_-10 1717288..1717299 /Source="Nicolas_upshift_promotors" /id="U1327" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.665334665334665" /psig="0.665334665334665" /xcortree=682 /SigmaFactorBS="aaaagtgatacaataatgaatttcaTGGTTAGcgagtgaaaa acatGTCAACACTATTatggcttttaagctttatgctccacggcgttcttctgtacgc t" /listShort="ylxL" /listLong="S586, rpsB, S587, tsf, S588, pyrH, frr, S589, uppS, cdsA, dxr, rseP, proS, S590, polC, S591, S592, S593, ylxS, nusA, ylxR, rplGA, infB, ylxP, rbfA, truB, ribC, S594, rpsO, S595, pnpA, S596, ylxY, mlpA" /label="promotor_-10" upshifts 1717302 /Source="Nicolas_upshifts" /id="U1327" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.665334665334665" /psig="0.665334665334665" /xcortree=682 /SigmaFactorBS="aaaagtgatacaataatgaatttcaTGGTTAGcgagtgaaaa acatGTCAACACTATTatggcttttaagctttatgctccacggcgttcttctgtacgc t" /listShort="ylxL" /listLong="S586, rpsB, S587, tsf, S588, pyrH, frr, S589, uppS, cdsA, dxr, rseP, proS, S590, polC, S591, S592, S593, ylxS, nusA, ylxR, rplGA, infB, ylxP, rbfA, truB, ribC, S594, rpsO, S595, pnpA, S596, ylxY, mlpA" promotor_-35 1717785..1717791 /Source="Nicolas_upshift_promotors" /id="U1328" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.782217782217782" /psig=1 /xcortree=2651 /SigmaFactorBS="ctatttttaaaatttcgctccaaaggtgtaaaggattCTTGA TTgtcggataaagctgTGTTATATTATGTCTTGGTGttaaatacacacgcttaacgat t" /listShort="S586, rpsB, S587, tsf, S588, pyrH, frr, S589, uppS, cdsA, dxr, rseP, proS, S590, polC, S591" /listLong="S592, S593, ylxS, nusA, ylxR, rplGA, infB, ylxP, rbfA, truB, ribC, S594, rpsO, S595, pnpA, S596, ylxY, mlpA" /label="promotor_-35" promotor_-10 1717806..1717825 /Source="Nicolas_upshift_promotors" /id="U1328" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.782217782217782" /psig=1 /xcortree=2651 /SigmaFactorBS="ctatttttaaaatttcgctccaaaggtgtaaaggattCTTGA TTgtcggataaagctgTGTTATATTATGTCTTGGTGttaaatacacacgcttaacgat t" /listShort="S586, rpsB, S587, tsf, S588, pyrH, frr, S589, uppS, cdsA, dxr, rseP, proS, S590, polC, S591" /listLong="S592, S593, ylxS, nusA, ylxR, rplGA, infB, ylxP, rbfA, truB, ribC, S594, rpsO, S595, pnpA, S596, ylxY, mlpA" /label="promotor_-10" S_feature 1717808..1717932 /Source="Nicolas_S_feature" /locus_tag="new_1717808_1717932" /HighExp="GM 45, GM 15, H2O2, M9-exp, LBGexp, C30, MG 90, GM-0.1, G135, SMM" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="1, 0.998" /TUlongSig="SigGF, SigD, SigA, SigA, SigA, SigA, SigD, SigA, SigA" /TUlongPSig="0.665, 1, 0.994, 0.998, 1, 0.999, 1, 1, 1" /label="S586" upshifts 1717808 /Source="Nicolas_upshifts" /id="U1328" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.782217782217782" /psig=1 /xcortree=2651 /SigmaFactorBS="ctatttttaaaatttcgctccaaaggtgtaaaggattCTTGA TTgtcggataaagctgTGTTATATTATGTCTTGGTGttaaatacacacgcttaacgat t" /listShort="S586, rpsB, S587, tsf, S588, pyrH, frr, S589, uppS, cdsA, dxr, rseP, proS, S590, polC, S591" /listLong="S592, S593, ylxS, nusA, ylxR, rplGA, infB, ylxP, rbfA, truB, ribC, S594, rpsO, S595, pnpA, S596, ylxY, mlpA" CDS 1717933..1718673 /gene="rpsB" /locus_tag="BSU_16490" /old_locus_tag="BSU16490" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 9090122, 10675340, 12682299; Product type s: structure" /codon_start=1 /transl_table=11 /product="ribosomal protein S2" /protein_id="NP_389531.1" /db_xref="EnsemblGenomes-Gn:BSU16490" /db_xref="EnsemblGenomes-Tr:CAB13522" /db_xref="GOA:P21464" /db_xref="InterPro:IPR001865" /db_xref="InterPro:IPR005706" /db_xref="InterPro:IPR018130" /db_xref="InterPro:IPR023591" /db_xref="PDB:3J9W" /db_xref="PDB:5NJT" /db_xref="SubtiList:BG19004" /db_xref="UniProtKB/Swiss-Prot:P21464" /translation="MSVISMKQLLEAGVHFGHQTRRWNPKMKRYIFTERNGIYIIDLQ KTVKKVEEAYNFTKNLAAEGGKILFVGTKKQAQDSVKEEAQRSGMYYVNQRWLGGTLT NFETIQKRIKRLKDIEKMQENGTFDVLPKKEVVQLKKELERLEKFLGGIKDMKDLPDA LFIIDPRKERIAVAEARKLNIPIIGIVDTNCDPDEIDVVIPANDDAIRAVKLLTSKMA DAILEAKQGEEEAEVAEETAPETETTTA*" gene 1717933..1718673 /gene="rpsB" /locus_tag="BSU_16490" /old_locus_tag="BSU16490" downshifts 1718655 /Source="Nicolas_upshifts" /id="D896" /incds=0 /nref=4 /ntot=61 /MaxReadThrough="9.04923" /MaxDrop="4.1312" /score="7.42766835" /energy="-14.3" /TU="U1324,U1328" /idTUdmin="U1323" /TUdmin=869 /isTUend="FALSE" S_feature 1718700..1718774 /Source="Nicolas_S_feature" /locus_tag="new_1718700_1718774" /HighExp="LPh, dia0, G150, G180, LBGexp, Lbexp, HPh, Oxctl, dia15, MG 15" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="1, 0.998" /TUlongSig="SigGF, SigD, SigA, SigA, SigA, SigA, SigD, SigA, SigA" /TUlongPSig="0.665, 1, 0.994, 0.998, 1, 0.999, 1, 1, 1" /label="S587" CDS 1718775..1719656 /gene="tsf" /locus_tag="BSU_16500" /old_locus_tag="BSU16500" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 6396082, 9244380, 9973356, 27624934; Product type f: factor" /codon_start=1 /transl_table=11 /product="elongation factor Ts" /protein_id="NP_389532.1" /db_xref="EnsemblGenomes-Gn:BSU16500" /db_xref="EnsemblGenomes-Tr:CAB13523" /db_xref="GOA:P80700" /db_xref="InterPro:IPR001816" /db_xref="InterPro:IPR009060" /db_xref="InterPro:IPR014039" /db_xref="InterPro:IPR018101" /db_xref="InterPro:IPR036402" /db_xref="SubtiList:BG19025" /db_xref="UniProtKB/Swiss-Prot:P80700" /translation="MAITAQQVKELREKTGAGMMDCKKALTETDGDMDKAIDLLREKG IAKAAKKADRIAAEGSTLIKTDGNKGVILEVNSETDFVAKNEGFKELLNTLADHLLAN TPADVEEAMGQKMENGSTVEEYITSAVAKIGEKITLRRFTVLTKDDSSAFGAYLHMGG RIGVLTVLNGTTDEETAKDIAMHVAAVNPRYISRDQVSEEETNHERQILTQQALQEGK PENIVAKMVEGRLNKFFEEICLLDQAFVKNPDEKVKQVIAAKNATVQTFVRYEVGEGI EKRQENFAEEVMNQVKK*" gene 1718775..1719656 /gene="tsf" /locus_tag="BSU_16500" /old_locus_tag="BSU16500" S_feature 1719657..1719801 /Source="Nicolas_S_feature" /locus_tag="new_1719657_1719801" /HighExp="LBGexp, G150, LBGtran, G135, G180, LPh, Oxctl, dia0, Lbexp, M9-exp" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="1, 0.998" /TUlongSig="SigGF, SigD, SigA, SigA, SigA, SigA, SigD, SigA, SigA" /TUlongPSig="0.665, 1, 0.994, 0.998, 1, 0.999, 1, 1, 1" /label="S588" CDS 1719802..1720524 /gene="pyrH" /locus_tag="BSU_16510" /old_locus_tag="BSU16510" /EC_number="2.7.4.22" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:9862121, 12682299, 12869195, 22720735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9862121, 12682299, 12869195, 22720735; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="uridylate kinase" /protein_id="NP_389533.2" /db_xref="EnsemblGenomes-Gn:BSU16510" /db_xref="EnsemblGenomes-Tr:CAB13524" /db_xref="GOA:O31749" /db_xref="InterPro:IPR001048" /db_xref="InterPro:IPR011817" /db_xref="InterPro:IPR015963" /db_xref="InterPro:IPR036393" /db_xref="SubtiList:BG12675" /db_xref="UniProtKB/Swiss-Prot:O31749" /translation="MEKPKYKRIVLKLSGEALAGEQGNGINPTVIQSIAKQVKEIAEL EVEVAVVVGGGNLWRGKTGSDLGMDRATADYMGMLATVMNSLALQDSLETLGIQSRVQ TSIEMRQVAEPYIRRKAIRHLEKKRVVIFAAGTGNPYFSTDTTAALRAAEIEADVILM AKNNVDGVYNADPRKDESAVKYESLSYLDVLKDGLEVMDSTASSLCMDNDIPLIVFSI MEEGNIKRAVIGESIGTIVRGK*" gene 1719802..1720524 /gene="pyrH" /locus_tag="BSU_16510" /old_locus_tag="BSU16510" CDS 1720526..1721083 /gene="frr" /locus_tag="BSU_16520" /old_locus_tag="BSU16520" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 9862121, 12480895, 12682299, 14586115; Product type f: factor" /codon_start=1 /transl_table=11 /product="ribosome recycling factor" /protein_id="NP_389534.1" /db_xref="EnsemblGenomes-Gn:BSU16520" /db_xref="EnsemblGenomes-Tr:CAB13525" /db_xref="GOA:P81101" /db_xref="InterPro:IPR002661" /db_xref="InterPro:IPR023584" /db_xref="InterPro:IPR036191" /db_xref="SubtiList:BG12587" /db_xref="UniProtKB/Swiss-Prot:P81101" /translation="MSKEVLTQTKEKMEKAIAAYQRELATVRAGRANPSLLDKVTVEY YGAQTPLNQLSSINVPEARMLVITPYDKTAIGDIEKAILKADLGLTPTSDGNMIRIAI PALTEERRKELVKVVKKYAEEAKVAVRNVRRDANDDLKKLEKNGDITEDELRASTEDV QKLTDEYVSKIDSVTKDKEKEIMEV*" gene 1720526..1721083 /gene="frr" /locus_tag="BSU_16520" /old_locus_tag="BSU16520" downshifts complement(1721030) /Source="Nicolas_upshifts" /id="D897" /incds=0 /nref=1 /ntot=70 /MaxReadThrough="3.38183" /MaxDrop="3.17183" /score="-5.69560888" /energy="-4.8" /TU="NA" /idTUdmin="U1326" /TUdmin="-10739" /isTUend="FALSE" promotor_-35 1721072..1721075 /Source="Nicolas_upshift_promotors" /id="U1329" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.616383616383616" /psig="0.773226773226773" /xcortree=536 /SigmaFactorBS="acaaaagacaaagaaaaagaaatcATGGaagtttaatgaaaa ACTATGTACAATAGATAATAgtgaaaagaccctctcatgtttacagggggtttttttg t" /listShort="S589, uppS, cdsA, dxr, rseP, proS, S590, polC, S591" /listLong="S592, S593, ylxS, nusA, ylxR, rplGA, infB, ylxP, rbfA, truB, ribC, S594, rpsO, S595, pnpA, S596, ylxY, mlpA" /label="promotor_-35" promotor_-10 1721090..1721109 /Source="Nicolas_upshift_promotors" /id="U1329" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.616383616383616" /psig="0.773226773226773" /xcortree=536 /SigmaFactorBS="acaaaagacaaagaaaaagaaatcATGGaagtttaatgaaaa ACTATGTACAATAGATAATAgtgaaaagaccctctcatgtttacagggggtttttttg t" /listShort="S589, uppS, cdsA, dxr, rseP, proS, S590, polC, S591" /listLong="S592, S593, ylxS, nusA, ylxR, rplGA, infB, ylxP, rbfA, truB, ribC, S594, rpsO, S595, pnpA, S596, ylxY, mlpA" /label="promotor_-10" S_feature 1721108..1721213 /Source="Nicolas_S_feature" /locus_tag="new_1721108_1721213" /HighExp="G180, G135, T3.30H, Oxctl, G150, Cold, Paraq, C30, T3.0H, T4.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA, SigA" /TUshortPSig="0.773, 1, 0.998" /TUlongSig="SigGF, SigD, SigA, SigA, SigA, SigA, SigD, SigA, SigA" /TUlongPSig="0.665, 1, 0.994, 0.998, 1, 0.999, 1, 1, 1" /label="S589" upshifts 1721108 /Source="Nicolas_upshifts" /id="U1329" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.616383616383616" /psig="0.773226773226773" /xcortree=536 /SigmaFactorBS="acaaaagacaaagaaaaagaaatcATGGaagtttaatgaaaa ACTATGTACAATAGATAATAgtgaaaagaccctctcatgtttacagggggtttttttg t" /listShort="S589, uppS, cdsA, dxr, rseP, proS, S590, polC, S591" /listLong="S592, S593, ylxS, nusA, ylxR, rplGA, infB, ylxP, rbfA, truB, ribC, S594, rpsO, S595, pnpA, S596, ylxY, mlpA" CDS 1721214..1721996 /gene="uppS" /locus_tag="BSU_16530" /old_locus_tag="BSU16530" /EC_number="2.5.1.31" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:15788389, 16014871, 22904278, 23840410, 27578312" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15788389, 16014871, 22904278, 23840410, 27578312; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="undecaprenyl pyrophosphate synthase" /protein_id="NP_389535.1" /db_xref="EnsemblGenomes-Gn:BSU16530" /db_xref="EnsemblGenomes-Tr:CAB13526" /db_xref="GOA:O31751" /db_xref="InterPro:IPR001441" /db_xref="InterPro:IPR018520" /db_xref="InterPro:IPR036424" /db_xref="SubtiList:BG13408" /db_xref="UniProtKB/Swiss-Prot:O31751" /translation="MLNILKNWKNQQTAASNLERYTKEDILKGEIPEHIAIIMDGNGR WAKKRSLPRIAGHHEGMKVVKRTTKLANELGVKVLTLYAFSTENWKRPKMEVDFLMKL PEEFLNTYLPELVEENVQVRIIGDETALPAHTLRAIEKAVQDTAQNDGMILNFALNYG GRTEIVSAAKSLAEKVKEGSLNIEDIDESLFSTYLMTESLQDPELLIRTSGEIRLSNF MLWQVAYSEFVFTDVLWPDFKEDHFLQALGEFQQRGRRFGGI*" gene 1721214..1721996 /gene="uppS" /locus_tag="BSU_16530" /old_locus_tag="BSU16530" CDS 1722000..1722809 /gene="cdsA" /locus_tag="BSU_16540" /old_locus_tag="BSU16540" /EC_number="2.7.7.41" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1c: Function from experimental evidences in the studied genus; PubMedId: 175832, 12682299, 15849754, 16850406; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="phosphatidate cytidylyltransferase (CDP-diglyceride synthase)" /protein_id="NP_389536.1" /db_xref="EnsemblGenomes-Gn:BSU16540" /db_xref="EnsemblGenomes-Tr:CAB13527" /db_xref="GOA:O31752" /db_xref="InterPro:IPR000374" /db_xref="SubtiList:BG12575" /db_xref="UniProtKB/Swiss-Prot:O31752" /translation="MVDMKQRILTGVLAAIVFLFLVIVGKLPFTILIYAMGSVALFEL LRMKKLKLVSLPGLIGLLLLWMFLLPSQYSFFEADGISKMEIALFAVLLLLTYTVLVK NTFTFDEVGFITLAAIYIGMCFHYFIEIRNLDQYGLTYIFYACVVIWSTDSGAYFVGK SLGKRKLWPEISPNKTVEGFAGGIVIALVLATIFQLVAQLPIPYIYLLLITLFLSVFG QLGDLVESALKRHYDVKDSGNILPGHGGILDRFDSFLFVMPFLYFLLALFS*" gene 1722000..1722809 /gene="cdsA" /locus_tag="BSU_16540" /old_locus_tag="BSU16540" promotor_-35 1722790..1722797 /Source="Nicolas_upshift_promotors" /id="U1330" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.958041958041958" /psig=1 /xcortree=2056 /SigmaFactorBS="gacagtttcttgtttgtcatgcctttcttgtactttcTGCTT GCCcttttttcataaaaAAGTCTAATATGAATATGAGactgatcatgcagcaataaga a" /listShort="dxr, rseP, proS, S590, polC, S591, S592" /listLong="S593, ylxS, nusA, ylxR, rplGA, infB, ylxP, rbfA, truB, ribC, S594, rpsO, S595, pnpA, S596, ylxY, mlpA" /label="promotor_-35" promotor_-10 1722812..1722831 /Source="Nicolas_upshift_promotors" /id="U1330" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.958041958041958" /psig=1 /xcortree=2056 /SigmaFactorBS="gacagtttcttgtttgtcatgcctttcttgtactttcTGCTT GCCcttttttcataaaaAAGTCTAATATGAATATGAGactgatcatgcagcaataaga a" /listShort="dxr, rseP, proS, S590, polC, S591, S592" /listLong="S593, ylxS, nusA, ylxR, rplGA, infB, ylxP, rbfA, truB, ribC, S594, rpsO, S595, pnpA, S596, ylxY, mlpA" /label="promotor_-10" upshifts 1722813 /Source="Nicolas_upshifts" /id="U1330" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.958041958041958" /psig=1 /xcortree=2056 /SigmaFactorBS="gacagtttcttgtttgtcatgcctttcttgtactttcTGCTT GCCcttttttcataaaaAAGTCTAATATGAATATGAGactgatcatgcagcaataaga a" /listShort="dxr, rseP, proS, S590, polC, S591, S592" /listLong="S593, ylxS, nusA, ylxR, rplGA, infB, ylxP, rbfA, truB, ribC, S594, rpsO, S595, pnpA, S596, ylxY, mlpA" CDS 1722871..1724022 /gene="dxr" /locus_tag="BSU_16550" /old_locus_tag="BSU16550" /EC_number="1.1.1.267" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:12682299, 15567415, 17458547, 21296950, 23840410" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12682299, 15567415, 17458547, 21296950, 23840410; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="1-deoxy-D-xylulose-5-phosphate reductoisomerase" /protein_id="NP_389537.2" /db_xref="EnsemblGenomes-Gn:BSU16550" /db_xref="EnsemblGenomes-Tr:CAB13528" /db_xref="GOA:O31753" /db_xref="InterPro:IPR003821" /db_xref="InterPro:IPR013512" /db_xref="InterPro:IPR013644" /db_xref="InterPro:IPR026877" /db_xref="InterPro:IPR036169" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG13409" /db_xref="UniProtKB/Swiss-Prot:O31753" /translation="MKNICLLGATGSIGEQTLDVLRAHQDQFQLVSMSFGRNIDKAVP MIEVFQPKFVSVGDLDTYHKLKQMSFSFECQIGLGEEGLIEAAVMEEVDIVVNALLGS VGLIPTLKAIEQKKTIALANKETLVTAGHIVKEHAKKYDVPLLPVDSEHSAIFQALQG EQAKNIERLIITASGGSFRDKTREELESVTVEDALKHPNWSMGAKITIDSATMMNKGL EVIEAHWLFDIPYEQIDVVLHKESIIHSMVEFHDKSVIAQLGTPDMRVPIQYALTYPD RLPLPDAKRLELWEIGSLHFEKADFDRFRCLQFAFESGKIGGTMPTVLNAANEVAVAA FLAGKIPFLAIEDCIEKALTRHQLLKKPSLADIQEVDKDTRGYVNSILT*" gene 1722871..1724022 /gene="dxr" /locus_tag="BSU_16550" /old_locus_tag="BSU16550" CDS 1724029..1725297 /gene="rasP" /locus_tag="BSU_16560" /old_locus_tag="BSU16560" /EC_number="3.4.24.-" /function="16.3: Control" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:15130127, 15496982, 15520285, 16014871, 16899079, 18599827, 19889088, 20644139, 21810987, 26735940, 28376795, 28674070" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15130127, 15496982, 15520285, 16014871, 16899079, 18599827, 19889088, 20644139, 21810987, 26735940, 28376795, 28674070; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="inner membrane zinc metalloprotease required forthe extracytoplasmic stress response mediated by sigma(W)" /protein_id="NP_389538.1" /db_xref="EnsemblGenomes-Gn:BSU16560" /db_xref="EnsemblGenomes-Tr:CAB13529" /db_xref="GOA:O31754" /db_xref="InterPro:IPR001478" /db_xref="InterPro:IPR004387" /db_xref="InterPro:IPR008915" /db_xref="InterPro:IPR036034" /db_xref="SubtiList:BG13410" /db_xref="UniProtKB/Swiss-Prot:O31754" /translation="MFVNTVIAFIIIFGTLVFFHELGHLLLAQRAGILCREFAIGFGP KIFSFKKNETVYTIRLLPVGGFVRMAGEDPEMIEVKPGYTVGLLFNKEDQVEKVIINQ KEKYPDALVIEVETADLEHDMKITGYEQGKEDELSSFTVSETSFFIVDGEEVQIAPYN RQFGSKPVWQRIKAIAAGPIMNFILAYVILVMLGLIQGVPSNEPMLGQLTDNGRAAEA GLKEGDYIQSINGEKMRSWTDIVSAVKENPEKEMDVAVKRDNKTLHISVTPEAVKDEN KKTIGRFGSYAPTEKGVLSAVAYGATSTVDVTKAILTNLSKLVTGQFKLDMLSGPVGI YDMTDQVAKTGIVNLFQFAAFLSINLGIVNLLPIPALDGGRLLFLFIEAIRGKPINRE KEAFVVFIGVAFLMLLMLVVTWNDIQRLFL*" gene 1724029..1725297 /gene="rasP" /locus_tag="BSU_16560" /old_locus_tag="BSU16560" CDS 1725330..1727024 /gene="proS" /locus_tag="BSU_16570" /old_locus_tag="BSU16570" /EC_number="6.1.1.15" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 12682299, 16864571, 26886480; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="prolyl-tRNA synthetase" /protein_id="NP_389539.1" /db_xref="EnsemblGenomes-Gn:BSU16570" /db_xref="EnsemblGenomes-Tr:CAB13530" /db_xref="GOA:O31755" /db_xref="InterPro:IPR002314" /db_xref="InterPro:IPR002316" /db_xref="InterPro:IPR004154" /db_xref="InterPro:IPR004500" /db_xref="InterPro:IPR006195" /db_xref="InterPro:IPR007214" /db_xref="InterPro:IPR023717" /db_xref="InterPro:IPR033730" /db_xref="InterPro:IPR036621" /db_xref="InterPro:IPR036754" /db_xref="SubtiList:BG12659" /db_xref="UniProtKB/Swiss-Prot:O31755" /translation="MRQSLTLIPTLREVPADAEAKSHQLLLRAGFIRQNTSGVYSYMP LAYKVIQNIQQIVREEMEKIDAVEMLMPALQQAETWQESGRWYTYGPELMRLKDRHGR EFALGATHEEVITSLVRDEVKSYKRLPLTLYQIQSKFRDEKRPRFGLLRGREFIMKDA YSFHASAESLDETYQKMYEAYSNIFARCGINVRPVIADSGAMGGKDTHEFMALSAIGE DTIAYSDESQYAANIEMAEVLHQEVPSDEEPKALEKVHTPNVKTIEELTAFLQVSAEA CIKSVLFKADDRFVLVLVRGDHEVNDIKVKNLLHAEVVELATHEEVIQQLGTEPGFVG PVGIHQDVEVYADQAVKAMVNAVAGANEGDHHYKNVNVNRDAQIKEFADLRFIKEGDP SPDGKGTIRFAEGIEVGQVFKLGTRYSEAMNATYLDENGRAQPMLMGCYGIGVSRTLS AIAEQHHDEKGLIWPKSVAPYDLHILALNMKNDGQRELAEKLYADLKAEGYEVLYDDR AERAGVKFADSDLIGLPIRITVGKRADEGIVEVKIRQTGESTEISVDELSAFISKQ*" gene 1725330..1727024 /gene="proS" /locus_tag="BSU_16570" /old_locus_tag="BSU16570" S_feature 1727025..1727132 /Source="Nicolas_S_feature" /locus_tag="new_1727025_1727132" /HighExp="G135, G180, G150, C30, Oxctl, H2O2, Paraq, LPh, LBGexp, BC" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA, SigA, SigA" /TUshortPSig="1, 0.773, 1, 0.998" /TUlongSig="SigGF, SigD, SigA, SigA, SigA, SigA, SigD, SigA, SigA" /TUlongPSig="0.665, 1, 0.994, 0.998, 1, 0.999, 1, 1, 1" /label="S590" CDS 1727133..1731446 /gene="polC" /locus_tag="BSU_16580" /old_locus_tag="BSU16580" /EC_number="2.7.7.7" /function="16.9: Replicate" /experiment="publication(s) with functional evidences, PMID:11721055, 12081953, 12217498, 20122408, 21740522, 24106089, 28575448" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11721055, 12081953, 12217498, 20122408, 21740522, 24106089, 28575448; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="DNA polymerase III (alpha subunit)" /protein_id="NP_389540.1" /db_xref="EnsemblGenomes-Gn:BSU16580" /db_xref="EnsemblGenomes-Tr:CAB13531" /db_xref="GOA:P13267" /db_xref="InterPro:IPR003141" /db_xref="InterPro:IPR004013" /db_xref="InterPro:IPR006054" /db_xref="InterPro:IPR006308" /db_xref="InterPro:IPR011708" /db_xref="InterPro:IPR012337" /db_xref="InterPro:IPR012340" /db_xref="InterPro:IPR013520" /db_xref="InterPro:IPR024754" /db_xref="InterPro:IPR028112" /db_xref="InterPro:IPR029460" /db_xref="InterPro:IPR036397" /db_xref="SubtiList:BG10263" /db_xref="UniProtKB/Swiss-Prot:P13267" /translation="MEQLSVNRRQFQILLQQINMTDDTFMTYFEHGEIKKLTIHKASK SWHFHFQFKSLLPFQIYDTLTTRLTQSFAHIAKVTSSIEVQDAEVSESIVQDYWSRCI EELQGISPPIISLLNQQKPKLKGNKLIVKTKTDTEAAALKNKYSSMIQAEYRQFGFPD LQLDAEIFVSEQEVQKFREQKLAEDQERAMQALIEMEKKDKESDEDQAPSGPLVIGYQ IKDNEEIRTLDSIMDEERRITVQGYVFDVETRELKSGRTLCIFKITDYTNSILIKMFA REKEDAALMKSLKKGMWVKARGSIQNDTFVRDLVMIANDVNEIKAKTREDSAPEGEKR VELHLHSPMSQMDAVTGIGKLVEQAKKWGHEAIALTDHAVVQSFPDAYSAAKKHGIKM IYGMEANLVDDGVPIAYNAAHRLLEEETYVVFDVETTGLSAVYDTIIELAAVKVKGGE IIDKFEAFANPHRPLSATIIELTGITDDMLQDAPDVVDVIRDFREWIGDDILVAHNAS FDMGFLNVAYKKLLEVEKAKNPVIDTLELGRFLYPEFKNHRLNTLCKKFDIELTQHHR AIYDTEATAYLLLKMLKDAAEKGIQYHDELNENMGQSNAYQRSRPYHATLLAVNSTGL KNLFKLVSLSHIHYFYRVPRIPRSQLEKYREGLLIGSACDRGEVFEGMMQKSPEEVED IASFYDYLEVQPPEVYRHLLELELVRDEKALKEIIANITKLGEKLNKPVVATGNVHYL NDEDKIYRKILISSQGGANPLNRHELPKVHFRTTDEMLEAFSFLGEEKAKEIVVTNTQ KVASLVDDIKPIKDDLYTPKIEGADEEIREMSYQRARSIYGEELPEIVEARIEKELKS IIGHGFAVIYLISHKLVKRSLDDGYLVGSRGSVGSSLVATLTEITEVNPLPPHYVCPE CQHSEFFNDGSVGSGFDLPDKTCPHCGTPLKKDGHDIPFETFLGFKGDKVPDIDLNFS GEYQPQAHNYTKVLFGEDNVYRAGTIGTVAEKTAYGYVKGYAGDNNLHMRGAEIDRLV QGCTGVKRTTGQHPGGIIVVPDYMDIYDFSPIQFPADATGSEWKTTHFDFHSIHDNLL KLDILGHDDPTVIRMLQDLSGIDPKTIPTDDPEVMKIFQGTESLGVTEEQIGCKTGTL GIPEFGTRFVRQMLEDTKPTTFSELVQISGLSHGTDVWLGNAQELIHNNICELSEVIG CRDDIMVYLIYQGLEPSLAFKIMEFVRKGKGLTPEWEEEMKNNNVPDWYIDSCKKIKY MFPKAHAAAYVLMAVRIAYFKVHHALLYYAAYFTVRADDFDIDTMIKGSTAIRAVMED INAKGLDASPKEKNLLTVLELALEMCERGYSFQKVDLYRSSATEFIIDGNSLIPPFNS IPGLGTNAALNIVKAREEGEFLSKEDLQKRGKVSKTILEYLDRHGCLESLPDQNQLSL F*" gene 1727133..1731446 /gene="polC" /locus_tag="BSU_16580" /old_locus_tag="BSU16580" S_feature 1731447..1731511 /Source="Nicolas_S_feature" /locus_tag="new_1731447_1731511" /HighExp="C30, G180, G135, Oxctl, G150, H2O2, Paraq, Cold, LBGstat, Glucon" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA, SigA, SigA" /TUshortPSig="1, 0.773, 1, 0.998" /TUlongSig="SigGF, SigD, SigA, SigA, SigA, SigD, SigA, SigA" /TUlongPSig="0.665, 1, 0.998, 1, 0.999, 1, 1, 1" /label="S591" misc_RNA 1731457..1731674 /gene="surG" /locus_tag="BSU_misc_RNA_71" /product="small RNAs controlled by sporulation" /experiment="publication(s) with functional evidences, PMID:16385044" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16385044; Product type n: RNA" gene 1731457..1731674 /gene="surG" /locus_tag="BSU_misc_RNA_71" promotor_-35 1731483..1731489 /Source="Nicolas_upshift_promotors" /id="U1331" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=881 /SigmaFactorBS="aagcagaatttctcagaaattctgcttctaTGCATACataag cgcaaaaagTGCCATCGTAATattagagtttctgtcacttgcttaggtatgaaggtaa g" /listShort="S592, S593, ylxS, nusA, ylxR, rplGA, infB, ylxP, rbfA, truB" /listLong="ribC, S594, rpsO, S595, pnpA, S596, ylxY" /label="promotor_-35" promotor_-10 1731504..1731515 /Source="Nicolas_upshift_promotors" /id="U1331" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=881 /SigmaFactorBS="aagcagaatttctcagaaattctgcttctaTGCATACataag cgcaaaaagTGCCATCGTAATattagagtttctgtcacttgcttaggtatgaaggtaa g" /listShort="S592, S593, ylxS, nusA, ylxR, rplGA, infB, ylxP, rbfA, truB" /listLong="ribC, S594, rpsO, S595, pnpA, S596, ylxY" /label="promotor_-10" S_feature 1731513..1731580 /Source="Nicolas_S_feature" /locus_tag="new_1731513_1731580" /HighExp="S7, S5, S4, S8, S6, S3, G180, C30, T5.0H, ferm" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigGF, SigA" /TUshortPSig="0.998, 1" /TUlongSig="SigA, SigA, SigGF, SigA, SigD, SigA, SigA, SigA, SigD, SigA, SigA" /TUlongPSig="0.773, 1, 0.665, 0.998, 1, 0.998, 1, 0.999, 1, 1, 1" /label="S592" upshifts 1731513 /Source="Nicolas_upshifts" /id="U1331" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=881 /SigmaFactorBS="aagcagaatttctcagaaattctgcttctaTGCATACataag cgcaaaaagTGCCATCGTAATattagagtttctgtcacttgcttaggtatgaaggtaa g" /listShort="S592, S593, ylxS, nusA, ylxR, rplGA, infB, ylxP, rbfA, truB" /listLong="ribC, S594, rpsO, S595, pnpA, S596, ylxY" promotor_-35 1731563..1731569 /Source="Nicolas_upshift_promotors" /id="U1332" /multdbtbs="SigA" /comp="M16" /sig="SigA" /pcomp="0.441558441558442" /psig=1 /xcortree=2495 /SigmaFactorBS="gtttctgtcacttgcttaggtatgaaggtaagcgtatatccA TTTGCAataaaaatatggtTATGGTATAGTTTTATTGGAaatgctaacgattaccgag g" /listShort="S593, ylxS, nusA, ylxR, rplGA, infB, ylxP, rbfA, truB, ribC, S594, rpsO, S595, pnpA, S596, ylxY" /listLong="mlpA" /label="promotor_-35" S_feature 1731582..1731775 /Source="Nicolas_S_feature" /locus_tag="new_1731582_1731775" /HighExp="LoTm, Cold, HPh, G180, Paraq, Oxctl, T-5.40H, BMM, G150, LPh" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigGF" /TUshortPSig="1, 0.998" /TUlongSig="SigA, SigA, SigA, SigGF, SigA, SigD, SigA, SigA, SigA, SigD, SigA, SigA" /TUlongPSig="1, 0.773, 1, 0.665, 0.998, 1, 0.998, 1, 0.999, 1, 1, 1" /label="S593" upshifts 1731582 /Source="Nicolas_upshifts" /id="U1332" /multdbtbs="SigA" /comp="M16" /sig="SigA" /pcomp="0.441558441558442" /psig=1 /xcortree=2495 /SigmaFactorBS="gtttctgtcacttgcttaggtatgaaggtaagcgtatatccA TTTGCAataaaaatatggtTATGGTATAGTTTTATTGGAaatgctaacgattaccgag g" /listShort="S593, ylxS, nusA, ylxR, rplGA, infB, ylxP, rbfA, truB, ribC, S594, rpsO, S595, pnpA, S596, ylxY" /listLong="mlpA" promotor_-10 1731583..1731602 /Source="Nicolas_upshift_promotors" /id="U1332" /multdbtbs="SigA" /comp="M16" /sig="SigA" /pcomp="0.441558441558442" /psig=1 /xcortree=2495 /SigmaFactorBS="gtttctgtcacttgcttaggtatgaaggtaagcgtatatccA TTTGCAataaaaatatggtTATGGTATAGTTTTATTGGAaatgctaacgattaccgag g" /listShort="S593, ylxS, nusA, ylxR, rplGA, infB, ylxP, rbfA, truB, ribC, S594, rpsO, S595, pnpA, S596, ylxY" /listLong="mlpA" /label="promotor_-10" CDS 1731776..1732246 /gene="rimP" /locus_tag="BSU_16590" /old_locus_tag="BSU16590" /function="16.8: Protect" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 15257761, 16014871, 19150615, 20188109, 21529161; Product type f: factor" /codon_start=1 /transl_table=11 /product="ribosome maturation factor" /protein_id="NP_389541.1" /db_xref="EnsemblGenomes-Gn:BSU16590" /db_xref="EnsemblGenomes-Tr:CAB13532" /db_xref="GOA:P32726" /db_xref="InterPro:IPR003728" /db_xref="InterPro:IPR028989" /db_xref="InterPro:IPR028998" /db_xref="InterPro:IPR035956" /db_xref="InterPro:IPR036847" /db_xref="SubtiList:BG10264" /db_xref="UniProtKB/Swiss-Prot:P32726" /translation="MSKKVTDTVQEMAQPIVDSLQLELVDIEFVKEGQSWFLRVFIDS DDGVDIEECAKVSEALSEKLDEADPISQNYFLEVSSPGAERPLKKKADFEKSLGKNVY IKTYEPIDGVKVFEGELAEFDGQTVTVEITIKTRKKRINIPYEKIANARLAVTF*" gene 1731776..1732246 /gene="rimP" /locus_tag="BSU_16590" /old_locus_tag="BSU16590" downshifts complement(1732097) /Source="Nicolas_upshifts" /id="D898" /incds=1 /nref=3 /ntot=136 /MaxReadThrough="2.08299" /MaxDrop="3.17419" /score="-8.18111474" /energy="-9.2" /TU="NA" /idTUdmin="U1333" /TUdmin=0 /isTUend="TRUE" CDS 1732281..1733396 /gene="nusA" /locus_tag="BSU_16600" /old_locus_tag="BSU16600" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:12682299, 15978071, 16707701, 16946247, 27571753, 28507243" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12682299, 15978071, 16707701, 16946247, 27571753, 28507243; Product type f : factor" /codon_start=1 /transl_table=11 /product="transcription translation coupling factor involved in Rho-dependent transcription termination" /protein_id="NP_389542.1" /db_xref="EnsemblGenomes-Gn:BSU16600" /db_xref="EnsemblGenomes-Tr:CAB13533" /db_xref="GOA:P32727" /db_xref="InterPro:IPR003029" /db_xref="InterPro:IPR004087" /db_xref="InterPro:IPR009019" /db_xref="InterPro:IPR010213" /db_xref="InterPro:IPR012340" /db_xref="InterPro:IPR013735" /db_xref="InterPro:IPR015946" /db_xref="InterPro:IPR022967" /db_xref="InterPro:IPR025249" /db_xref="InterPro:IPR030842" /db_xref="InterPro:IPR036555" /db_xref="PDB:2MT4" /db_xref="SubtiList:BG10265" /db_xref="UniProtKB/Swiss-Prot:P32727" /translation="MSSELLDALTILEKEKGISKEIIIEAIEAALISAYKRNFNQAQN VRVDLNRETGSIRVFARKDVVDEVYDQRLEISIEEAQGIHPEYMVGDVVEIEVTPKDF GRIAAQTAKQVVTQRVREAERGVIYSEFIDREEDIMTGIVQRLDNKFIYVSLGKIEAL LPVNEQMPNESYKPHDRIKVYITKVEKTTKGPQIYVSRTHPGLLKRLFEIEVPEIYDG TVELKSVAREAGDRSKISVRTDDPDVDPVGSCVGPKGQRVQAIVNELKGEKIDIVNWS SDPVEFVANALSPSKVLDVIVNEEEKATTVIVPDYQLSLAIGKRGQNARLAAKLTGWK IDIKSETDARELGIYPRELEEDDEPLFTEPETAESDE*" gene 1732281..1733396 /gene="nusA" /locus_tag="BSU_16600" /old_locus_tag="BSU16600" promotor_no_box complement(1732343..1732443) /Source="Nicolas_upshift_promotors" /id="U1333" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.775224775224775" /psig="0.171828171828172" /xcortree=61 /SigmaFactorBS="agccagtttcacggtttagatccacccgtacattttgcgctt gattaaaattccgcttataagcagaaattaacgcagcttcgattgcttcgatgataat t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_no_box" upshifts complement(1732383) /Source="Nicolas_upshifts" /id="U1333" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.775224775224775" /psig="0.171828171828172" /xcortree=61 /SigmaFactorBS="agccagtttcacggtttagatccacccgtacattttgcgctt gattaaaattccgcttataagcagaaattaacgcagcttcgattgcttcgatgataat t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" CDS 1733410..1733685 /gene="rulR" /locus_tag="BSU_16610" /old_locus_tag="BSU16610" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 11679764, 12682299, 26771646, 27435445; Product type f: factor" /codon_start=1 /transl_table=11 /product="molecular ruler co-factor for RNA; new fold" /protein_id="NP_389543.1" /db_xref="EnsemblGenomes-Gn:BSU16610" /db_xref="EnsemblGenomes-Tr:CAB13534" /db_xref="InterPro:IPR007393" /db_xref="InterPro:IPR035931" /db_xref="SubtiList:BG10266" /db_xref="UniProtKB/Swiss-Prot:P32728" /translation="MNKHKKIPLRKCVVTGEMKPKKELIRVVRSKEGEISVDPTGKKN GRGAYLTLDKECILAAKKKNTLQNQFQSQIDDQIFDELLELAEKVKK*" gene 1733410..1733685 /gene="rulR" /locus_tag="BSU_16610" /old_locus_tag="BSU16610" CDS 1733687..1733989 /gene="rulQ" /locus_tag="BSU_16620" /old_locus_tag="BSU16620" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:15130481, 15361074, 22355167, 26522935, 26771646" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15130481, 15361074, 22355167, 26522935, 26771646; Product type f: factor" /codon_start=1 /transl_table=11 /product="K-turn RNA binding protein" /protein_id="NP_389544.1" /db_xref="EnsemblGenomes-Gn:BSU16620" /db_xref="EnsemblGenomes-Tr:CAB13535" /db_xref="GOA:P32729" /db_xref="InterPro:IPR004037" /db_xref="InterPro:IPR004038" /db_xref="InterPro:IPR029064" /db_xref="PDB:3V7Q" /db_xref="SubtiList:BG10267" /db_xref="UniProtKB/Swiss-Prot:P32729" /translation="MSGMEWFPLLGLANRARKVVSGEDLVIKEIRNARAKLVLLTEDA SSNTAKKVTDKCNYYKVPYKKVESRAVLGRSIGKEARVVVAVTDQGFANKLISLLD*" gene 1733687..1733989 /gene="rulQ" /locus_tag="BSU_16620" /old_locus_tag="BSU16620" CDS 1734009..1736159 /gene="infB" /locus_tag="BSU_16630" /old_locus_tag="BSU16630" /function="16.3: Control" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:1426242, 9588797, 12682299, 22720735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1426242, 9588797, 12682299, 22720735; Product type f: factor" /codon_start=1 /transl_table=11 /product="initiation factor IF-2" /protein_id="NP_389545.1" /db_xref="EnsemblGenomes-Gn:BSU16630" /db_xref="EnsemblGenomes-Tr:CAB13536" /db_xref="GOA:P17889" /db_xref="InterPro:IPR000178" /db_xref="InterPro:IPR000795" /db_xref="InterPro:IPR005225" /db_xref="InterPro:IPR006847" /db_xref="InterPro:IPR009000" /db_xref="InterPro:IPR015760" /db_xref="InterPro:IPR023115" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR036925" /db_xref="SubtiList:BG10268" /db_xref="UniProtKB/Swiss-Prot:P17889" /translation="MAKMRVYEYAKALNVSSKEILTALKNMDLEVNNHMAMLEEKAIK KLDAKYKKGGAAAKSQKPAETNKNKQPQGVNQQSAGNQPNKIRDGKKNDVQNNQFNKN KKNNNNKKNKRNNNNNKNQHQQKPVKPKKELPEKITFSGTLTVGALAEELGKEPSELI KKLMLLGVMATINQELDKDTIELIASEYGVETEEVIVLEETELEKYEEPDNEEDLEIR PPVVTIMGHVDHGKTTLLDSIRKTKVVEGEAGGITQHIGAYQIEENGKKITFLDTPGH AAFTTMRARGAEVTDITILVVAADDGVMPQTVEAINHAKAAEVPIIVAVNKIDKESAN PDRVMQELTEYGLVPEAWGGETIFVPLSALTGKGIDELVEMILLVSEVEELKANPNRQ AKGTVIEAELDKGRGSVATLLVQTGTLHVGDPIVVGNTFGRVRAMVNDIGRRVKTAGP STPVEITGLNDVPQAGDQFLVFKDEKTARSVGEARASKQLEEQRSDKAKLSLDDLFEQ IKQGDVKDINLIVKADVQGSAEALTAALQKIEVEGVKVKIIHTGVGAITESDIILASA SNAIVIGFNVRPDGNAKSTAEAENVDIRLHRIIYKVIDEIEAAMKGMLDPEYEEKVIG QVEVRQTFKVSKIGTIAGGYVTEGTITRDSGLRLIRDGVVIFEGEVDVLKRFKDDVKE VSQGYECGITIKKYNDIREGDILEAFVMQEIERT*" gene 1734009..1736159 /gene="infB" /locus_tag="BSU_16630" /old_locus_tag="BSU16630" promotor_-35 1736054..1736060 /Source="Nicolas_upshift_promotors" /id="U1334" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.797202797202797" /psig="0.797202797202797" /xcortree=274 /SigmaFactorBS="aggcgaagtagatgttctgaaacgctttaaagacgatgtgaa agaAGTTTCAcaaggctatgaatgTGGTATTACAATTAAGAAAtacaatgacattcgt g" /listShort="ylxP, rbfA, truB, ribC, S594, rpsO, S595, pnpA, S596, ylxY" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 1736069 /Source="Nicolas_upshifts" /id="U1334" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.797202797202797" /psig="0.797202797202797" /xcortree=274 /SigmaFactorBS="aggcgaagtagatgttctgaaacgctttaaagacgatgtgaa agaAGTTTCAcaaggctatgaatgTGGTATTACAATTAAGAAAtacaatgacattcgt g" /listShort="ylxP, rbfA, truB, ribC, S594, rpsO, S595, pnpA, S596, ylxY" /GFF_Attribute="listLong" promotor_-10 1736075..1736093 /Source="Nicolas_upshift_promotors" /id="U1334" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.797202797202797" /psig="0.797202797202797" /xcortree=274 /SigmaFactorBS="aggcgaagtagatgttctgaaacgctttaaagacgatgtgaa agaAGTTTCAcaaggctatgaatgTGGTATTACAATTAAGAAAtacaatgacattcgt g" /listShort="ylxP, rbfA, truB, ribC, S594, rpsO, S595, pnpA, S596, ylxY" /GFF_Attribute="listLong" /label="promotor_-10" CDS 1736156..1736434 /gene="ylxP" /locus_tag="BSU_16640" /old_locus_tag="BSU16640" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /pseudo /codon_start=1 /transl_table=11 /product="fragment of conserved protein" /db_xref="EnsemblGenomes-Gn:BSU16640" /db_xref="EnsemblGenomes-Tr:CAB13537" /db_xref="InterPro:IPR007546" /db_xref="InterPro:IPR036746" /db_xref="PSEUDO:CAB13537.1" /db_xref="SubtiList:BG10269" /db_xref="UniProtKB/Swiss-Prot:P32730" /translation="MIGFAECECIIYDAGSLKEKRAVLKRILTRVQNKFNVSISEIGY QDTWQRTSFGIAAVSSSRVQTEKELQRVLAFIDSFPEIERTITRTEWF*" gene 1736156..1736434 /gene="ylxP" /locus_tag="BSU_16640" /old_locus_tag="BSU16640" /pseudo CDS 1736451..1736804 /gene="rbfA" /locus_tag="BSU_16650" /old_locus_tag="BSU16650" /function="16.2: Construct biomass (Anabolism)" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 12628255, 15185964, 17996707, 21102555, 21529161, 23293003, 23611982, 24671761, 25904134, 27382067; Product type f: factor" /codon_start=1 /transl_table=11 /product="pre-ribosomal (17S) RNA binding factor A" /protein_id="NP_389547.1" /db_xref="EnsemblGenomes-Gn:BSU16650" /db_xref="EnsemblGenomes-Tr:CAB13538" /db_xref="GOA:P32731" /db_xref="InterPro:IPR000238" /db_xref="InterPro:IPR015946" /db_xref="InterPro:IPR020053" /db_xref="InterPro:IPR023799" /db_xref="SubtiList:BG10270" /db_xref="UniProtKB/Swiss-Prot:P32731" /translation="MSMRANRVGEQMKKELGDIISRKLKDPRIGFLTVTDVRVSGDLQ IAKVYISVLGDEKKREEALKGLAKAKGFIRSEIGSRIRLRKTPEIEFEFDESIDYGNR IETLIHELHSEKPSE*" gene 1736451..1736804 /gene="rbfA" /locus_tag="BSU_16650" /old_locus_tag="BSU16650" downshifts 1736795 /Source="Nicolas_upshifts" /id="D899" /incds=0 /nref=9 /ntot=130 /MaxReadThrough="6.97196" /MaxDrop="5.80207" /score="-3.06560848" /energy="-13.8" /TU="U1331,U1332,U1334" /idTUdmin="U1331" /TUdmin="-308" /isTUend="FALSE" CDS 1736886..1737815 /gene="truB" /locus_tag="BSU_16660" /old_locus_tag="BSU16660" /EC_number="5.4.99.25" /function="16.6: Maintain" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 7489483, 15987897; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="tRNA pseudouridine 55 synthase" /protein_id="NP_389548.1" /db_xref="EnsemblGenomes-Gn:BSU16660" /db_xref="EnsemblGenomes-Tr:CAB13539" /db_xref="GOA:P32732" /db_xref="InterPro:IPR002501" /db_xref="InterPro:IPR014780" /db_xref="InterPro:IPR020103" /db_xref="InterPro:IPR032819" /db_xref="SubtiList:BG10271" /db_xref="UniProtKB/Swiss-Prot:P32732" /translation="MVNGVLLLHKPVGMTSHDCVMKIRKLLKTKKVGHTGTLDPEVSG VLPICVGRATKIVEYLTEKSKTYDAEITLGFSTTTEDQTGETVETKPVNHDIDKADVE KVLNSLKGKQEQIPPMYSAVKVNGKKLYEYARAGIEVERPKRMITIEDIALTTEIKHH GETASFRFTVTCSKGTYVRTLAVMIGEKLGYPAHMSHLIRTASGDFSLDECFTFDELE AQAQSGTVEEHTVPIERALNHLPKWIISDTLAKKVENGALLETPEQFSEMTSGDRIAV FTESGTCLAIYFPHPAKKGLLKPAKVLMQKSEQ*" gene 1736886..1737815 /gene="truB" /locus_tag="BSU_16660" /old_locus_tag="BSU16660" promotor_-35 1737600..1737607 /Source="Nicolas_upshift_promotors" /id="U1335" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.938061938061938" /psig=1 /xcortree=1975 /SigmaFactorBS="catacagttcctattgaacgtgcgctcaatCATTTGCCgaaa tggatcataAGTGATACATTAGCTAAGAAagtagaaaatggggctttgcttgagacgc c" /listShort="ribC, S594, rpsO, S595, pnpA, S596, ylxY, mlpA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1737621..1737640 /Source="Nicolas_upshift_promotors" /id="U1335" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.938061938061938" /psig=1 /xcortree=1975 /SigmaFactorBS="catacagttcctattgaacgtgcgctcaatCATTTGCCgaaa tggatcataAGTGATACATTAGCTAAGAAagtagaaaatggggctttgcttgagacgc c" /listShort="ribC, S594, rpsO, S595, pnpA, S596, ylxY, mlpA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1737630 /Source="Nicolas_upshifts" /id="U1335" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.938061938061938" /psig=1 /xcortree=1975 /SigmaFactorBS="catacagttcctattgaacgtgcgctcaatCATTTGCCgaaa tggatcataAGTGATACATTAGCTAAGAAagtagaaaatggggctttgcttgagacgc c" /listShort="ribC, S594, rpsO, S595, pnpA, S596, ylxY, mlpA" /GFF_Attribute="listLong" CDS 1737834..1738784 /gene="ribC" /locus_tag="BSU_16670" /old_locus_tag="BSU16670" /EC_number="2.7.1.26" /EC_number="2.7.7.2" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:9473052, 10206712, 12456892, 15668000, 18156273, 21866869" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9473052, 10206712, 12456892, 15668000, 18156273, 21866869; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="bifunctional riboflavin kinase FAD synthase" /protein_id="NP_389549.1" /db_xref="EnsemblGenomes-Gn:BSU16670" /db_xref="EnsemblGenomes-Tr:CAB13540" /db_xref="GOA:P54575" /db_xref="InterPro:IPR002606" /db_xref="InterPro:IPR004821" /db_xref="InterPro:IPR014729" /db_xref="InterPro:IPR015864" /db_xref="InterPro:IPR015865" /db_xref="InterPro:IPR023465" /db_xref="InterPro:IPR023468" /db_xref="SubtiList:BG11495" /db_xref="UniProtKB/Swiss-Prot:P54575" /translation="MKTIHITHPHHLIKEEQAKSVMALGYFDGVHLGHQKVIGTAKQI AEEKGLTLAVMTFHPHPSHVLGRDKEPKDLITPLEDKINQIEQLGTEVLYVVKFNEVF ASLSPKQFIDQYIIGLNVQHAVAGFDFTYGKYGKGTMKTMPDDLDGKAGCTMVEKLTE QDKKISSSYIRTALQNGDVELANVLLGQPYFIKGIVIHGDKRGRTIGFPTANVGLNNS YIVPPTGVYAVKAEVNGEVYNGVCNIGYKPTFYEKRPEQPSIEVNLFDFNQEVYGAAI KIEWYKRIRSERKFNGIKELTEQIEKDKQEAIRYFSNLRK*" gene 1737834..1738784 /gene="ribC" /locus_tag="BSU_16670" /old_locus_tag="BSU16670" promotor_-35 1738817..1738823 /Source="Nicolas_upshift_promotors" /id="U1336" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.769230769230769" /psig="0.999000999001" /xcortree=2654 /SigmaFactorBS="ttcagcaatttgcggaaataacttgcaacgcacgcaaatttt attctaaaataTTTGCATataggcacgattttTAGTATGATAGTTTTCGTAGtcttaa a" /listShort="S594, rpsO, S595, pnpA, S596, ylxY, mlpA" /GFF_Attribute="listLong" /label="promotor_-35" S_feature 1738824..1738940 /Source="Nicolas_S_feature" /locus_tag="new_1738824_1738940" /HighExp="SMM, GM 15, Salt, T-4.40H, GM 45, T-5.40H, GM 60, MG 45, LPhT, MG t5" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA, SigB, SigA" /TUshortPSig="0.999, 1, 0.797, 1" /TUlongSig="SigGF, SigA, SigA, SigA, SigGF, SigA, SigD, SigA, SigA, SigA, SigD, SigA, SigA" /TUlongPSig="0.998, 1, 0.773, 1, 0.665, 0.998, 1, 0.998, 1, 0.999, 1, 1, 1" /label="S594" upshifts 1738824 /Source="Nicolas_upshifts" /id="U1336" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.769230769230769" /psig="0.999000999001" /xcortree=2654 /SigmaFactorBS="ttcagcaatttgcggaaataacttgcaacgcacgcaaatttt attctaaaataTTTGCATataggcacgattttTAGTATGATAGTTTTCGTAGtcttaa a" /listShort="S594, rpsO, S595, pnpA, S596, ylxY, mlpA" /GFF_Attribute="listLong" promotor_-10 1738838..1738857 /Source="Nicolas_upshift_promotors" /id="U1336" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.769230769230769" /psig="0.999000999001" /xcortree=2654 /SigmaFactorBS="ttcagcaatttgcggaaataacttgcaacgcacgcaaatttt attctaaaataTTTGCATataggcacgattttTAGTATGATAGTTTTCGTAGtcttaa a" /listShort="S594, rpsO, S595, pnpA, S596, ylxY, mlpA" /GFF_Attribute="listLong" /label="promotor_-10" CDS 1738941..1739210 /gene="rpsO" /locus_tag="BSU_16680" /old_locus_tag="BSU16680" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:12682299, 15627386, 8825778, 20418391, 22720735, 23611891" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12682299, 15627386, 8825778, 20418391, 22720735, 23611891; Product type s : structure" /codon_start=1 /transl_table=11 /product="ribosomal protein S15 (BS18)" /protein_id="NP_389550.1" /db_xref="EnsemblGenomes-Gn:BSU16680" /db_xref="EnsemblGenomes-Tr:CAB13541" /db_xref="GOA:P21473" /db_xref="InterPro:IPR000589" /db_xref="InterPro:IPR005290" /db_xref="InterPro:IPR009068" /db_xref="PDB:3J9W" /db_xref="PDB:5NJT" /db_xref="SubtiList:BG19010" /db_xref="UniProtKB/Swiss-Prot:P21473" /translation="MAITQERKNQLINEFKTHESDTGSPEVQIAILTDSINNLNEHLR THKKDHHSRRGLLKMVGKRRNLLTYLRNKDVTRYRELINKLGLRR*" gene 1738941..1739210 /gene="rpsO" /locus_tag="BSU_16680" /old_locus_tag="BSU16680" downshifts 1739193 /Source="Nicolas_upshifts" /id="D900" /incds=0 /nref=30 /ntot=154 /MaxReadThrough="8.65904" /MaxDrop="5.6648" /score="29.9198852" /energy="-10.2" /TU="U1332,U1334,U1335,U1336" /idTUdmin="U1331" /TUdmin=2090 /isTUend="FALSE" S_feature 1739238..1739323 /Source="Nicolas_S_feature" /locus_tag="new_1739238_1739323" /HighExp="Cold, LoTm, Oxctl, G180, H2O2, G150, dia15, Paraq, LPh, G135" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA, SigB, SigA" /TUshortPSig="0.999, 1, 0.797, 1" /TUlongSig="SigGF, SigA, SigA, SigA, SigGF, SigA, SigD, SigA, SigA, SigA, SigD, SigA, SigA" /TUlongPSig="0.998, 1, 0.773, 1, 0.665, 0.998, 1, 0.998, 1, 0.999, 1, 1, 1" /label="S595" promotor_-35 1739304..1739307 /Source="Nicolas_upshift_promotors" /id="U1337" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.798201798201798" /psig="0.999000999001" /xcortree=2126 /SigmaFactorBS="ataacaaatcattgaaatccttttacatactactttgacATT GatatgttcaattcatTTCGTTCATAATAGGAGTAAttgattatttcacacaacgaag a" /listShort="pnpA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1739323..1739342 /Source="Nicolas_upshift_promotors" /id="U1337" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.798201798201798" /psig="0.999000999001" /xcortree=2126 /SigmaFactorBS="ataacaaatcattgaaatccttttacatactactttgacATT GatatgttcaattcatTTCGTTCATAATAGGAGTAAttgattatttcacacaacgaag a" /listShort="pnpA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1739325 /Source="Nicolas_upshifts" /id="U1337" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.798201798201798" /psig="0.999000999001" /xcortree=2126 /SigmaFactorBS="ataacaaatcattgaaatccttttacatactactttgacATT GatatgttcaattcatTTCGTTCATAATAGGAGTAAttgattatttcacacaacgaag a" /listShort="pnpA" /GFF_Attribute="listLong" CDS 1739383..1741500 /gene="pnpA" /locus_tag="BSU_16690" /old_locus_tag="BSU16690" /EC_number="2.7.7.8" /EC_number="3.1.13.1" /function="16.2: Construct biomass (Anabolism)" /function="16.3: Control" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:8636041, 8825779, 9179491, 10572137, 15805522, 19215769, 19433509, 20659169, 21859751, 22568516, 25099370, 27708634" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8636041, 8825779, 9179491, 10572137, 15805522, 19215769, 19433509, 20659169, 21859751, 22568516, 25099370, 27708634; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="polynucleotide phosphorylase (PNPase)" /protein_id="NP_389551.1" /db_xref="EnsemblGenomes-Gn:BSU16690" /db_xref="EnsemblGenomes-Tr:CAB13542" /db_xref="GOA:P50849" /db_xref="InterPro:IPR001247" /db_xref="InterPro:IPR003029" /db_xref="InterPro:IPR004087" /db_xref="InterPro:IPR004088" /db_xref="InterPro:IPR012162" /db_xref="InterPro:IPR012340" /db_xref="InterPro:IPR015847" /db_xref="InterPro:IPR015848" /db_xref="InterPro:IPR020568" /db_xref="InterPro:IPR022967" /db_xref="InterPro:IPR027408" /db_xref="InterPro:IPR036345" /db_xref="InterPro:IPR036456" /db_xref="InterPro:IPR036612" /db_xref="SubtiList:BG11491" /db_xref="UniProtKB/Swiss-Prot:P50849" /translation="MGQEKHVFTIDWAGRTLTVETGQLAKQANGAVMIRYGDTAVLST ATASKEPKPLDFFPLTVNYEERLYAVGKIPGGFIKREGRPSEKAVLASRLIDRPIRPL FADGFRNEVQVISIVMSVDQNCSSEMAAMFGSSLALSVSDIPFEGPIAGVTVGRIDDQ FIINPTVDQLEKSDINLVVAGTKDAINMVEAGADEVPEEIMLEAIMFGHEEIKRLIAF QEEIVAAVGKEKSEIKLFEIDEELNEKVKALAEEDLLKAIQVHEKHAREDAINEVKNA VVAKFEDEEHDEDTIKQVKQILSKLVKNEVRRLITEEKVRPDGRGVDQIRPLSSEVGL LPRTHGSGLFTRGQTQALSVCTLGALGDVQILDGLGVEESKRFMHHYNFPQFSVGETG PMRGPGRREIGHGALGERALEPVIPSEKDFPYTVRLVSEVLESNGSTSQASICASTLA MMDAGVPIKAPVAGIAMGLVKSGEHYTVLTDIQGMEDALGDMDFKVAGTEKGVTALQM DIKIEGLSREILEEALQQAKKGRMEILNSMLATLSESRKELSRYAPKILTMTINPDKI RDVIGPSGKQINKIIEETGVKIDIEQDGTIFISSTDESGNQKAKKIIEDLVREVEVGQ LYLGKVKRIEKFGAFVEIFSGKDGLVHISELALERVGKVEDVVKIGDEILVKVTEIDK QGRVNLSRKAVLREEKEKEEQQS*" gene 1739383..1741500 /gene="pnpA" /locus_tag="BSU_16690" /old_locus_tag="BSU16690" downshifts 1741283 /Source="Nicolas_upshifts" /id="D901" /incds=1 /nref=1 /ntot=1 /MaxReadThrough="8.05841" /MaxDrop="3.82025" /score="-9.33432702" /energy="-7.8" /TU="U1332,U1334,U1335,U1336,U1337" /idTUdmin="U1337" /TUdmin="-198" /isTUend="FALSE" downshifts 1741484 /Source="Nicolas_upshifts" /id="D902" /incds=0 /nref=192 /ntot=270 /MaxReadThrough="5.61214" /MaxDrop="6.82185" /score="-9.33432702" /energy="-7.8" /TU="U1332,U1334,U1335,U1336" /idTUdmin="U1337" /TUdmin=3 /isTUend="TRUE" S_feature 1741529..1741617 /Source="Nicolas_S_feature" /locus_tag="new_1741529_1741617" /HighExp="G135, G180, G150, H2O2, Oxctl, LBGexp, Paraq, LoTm, LPh, dia15" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA, SigB, SigA" /TUshortPSig="0.999, 1, 0.797, 1" /TUlongSig="SigGF, SigA, SigA, SigA, SigGF, SigA, SigD, SigA, SigA, SigA, SigD, SigA, SigA" /TUlongPSig="0.998, 1, 0.773, 1, 0.665, 0.998, 1, 0.998, 1, 0.999, 1, 1, 1" /label="S596" CDS 1741618..1742577 /gene="ylxY" /locus_tag="BSU_16700" /old_locus_tag="BSU16700" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 14679227; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative sugar deacetylase" /protein_id="NP_389552.1" /db_xref="EnsemblGenomes-Gn:BSU16700" /db_xref="EnsemblGenomes-Tr:CAB13543" /db_xref="GOA:P50850" /db_xref="InterPro:IPR002509" /db_xref="InterPro:IPR010916" /db_xref="InterPro:IPR011330" /db_xref="InterPro:IPR014228" /db_xref="SubtiList:BG11492" /db_xref="UniProtKB/Swiss-Prot:P50850" /translation="MYKKFVPFAVFLFLFFVSFEMMENPHALDYIGAMKKDTVTVTAS KDPLYEELLQKAPEYEVKPQNARIDKVWKSIPGYNGLKVNIEQSYKKMKQHGKFREKD LVYSQVKPSVHLESLQPEPIYKGNPDKPMVAFLINVAWGNEYLEKMLPILQKHQVKAT FFLEGNWVRNNVQLAKKIAKDGHEIGNHSYNHPDMSKLTTGRISEQLDKTNEQIEQTI GVKPKWFAPPSGSFRKAVIDIAAEKQMGTVMWTVDTIDWQKPAPSVLQTRVLSKIHNG AMILMHPTDPTAESLEALITQIKDKGYALGTVTELMDETRLLK*" gene 1741618..1742577 /gene="ylxY" /locus_tag="BSU_16700" /old_locus_tag="BSU16700" promotor_-10 complement(1741686..1741694) /Source="Nicolas_upshift_promotors" /id="U1338" /multdbtbs="-" /comp="M2" /sig="SigI" /pcomp="0.645354645354645" /psig="0.645354645354645" /xcortree=686 /SigmaFactorBS="tgacgccgtgacagtcaccgtatcttttttcattGCCCCTAT ataatcaagtgcaTGCGGATTTtccatcatctcaaatgagacaaaaaaaagaaataaa a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1741689) /Source="Nicolas_upshifts" /id="U1338" /multdbtbs="-" /comp="M2" /sig="SigI" /pcomp="0.645354645354645" /psig="0.645354645354645" /xcortree=686 /SigmaFactorBS="tgacgccgtgacagtcaccgtatcttttttcattGCCCCTAT ataatcaagtgcaTGCGGATTTtccatcatctcaaatgagacaaaaaaaagaaataaa a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(1741708..1741715) /Source="Nicolas_upshift_promotors" /id="U1338" /multdbtbs="-" /comp="M2" /sig="SigI" /pcomp="0.645354645354645" /psig="0.645354645354645" /xcortree=686 /SigmaFactorBS="tgacgccgtgacagtcaccgtatcttttttcattGCCCCTAT ataatcaagtgcaTGCGGATTTtccatcatctcaaatgagacaaaaaaaagaaataaa a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1742181..1742186 /Source="Nicolas_upshift_promotors" /id="U1339" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.644355644355644" /psig="0.644355644355644" /xcortree=1044 /SigmaFactorBS="agattgcaaaagacggacatgaaatcggaaatcaTTCATAca atcatccggatatGAGCAAACTGACTACAGGAagaatttccgagcagctcgacaagac t" /listShort="mlpA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1742202..1742220 /Source="Nicolas_upshift_promotors" /id="U1339" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.644355644355644" /psig="0.644355644355644" /xcortree=1044 /SigmaFactorBS="agattgcaaaagacggacatgaaatcggaaatcaTTCATAca atcatccggatatGAGCAAACTGACTACAGGAagaatttccgagcagctcgacaagac t" /listShort="mlpA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1742207 /Source="Nicolas_upshifts" /id="U1339" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.644355644355644" /psig="0.644355644355644" /xcortree=1044 /SigmaFactorBS="agattgcaaaagacggacatgaaatcggaaatcaTTCATAca atcatccggatatGAGCAAACTGACTACAGGAagaatttccgagcagctcgacaagac t" /listShort="mlpA" /GFF_Attribute="listLong" CDS 1742617..1743846 /gene="mlpA" /locus_tag="BSU_16710" /old_locus_tag="BSU16710" /EC_number="3.4.24.-" /function="16.6: Maintain" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:10666719, 10974125" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10666719, 10974125; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="specific processing protease" /protein_id="NP_389553.2" /db_xref="EnsemblGenomes-Gn:BSU16710" /db_xref="EnsemblGenomes-Tr:CAB13544" /db_xref="GOA:Q04805" /db_xref="InterPro:IPR001431" /db_xref="InterPro:IPR007863" /db_xref="InterPro:IPR011249" /db_xref="InterPro:IPR011765" /db_xref="SubtiList:BG10779" /db_xref="UniProtKB/Swiss-Prot:Q04805" /translation="MIKRYTCQNGVRIVLENNPTVRSVAIGVWIGTGSRHETPEINGI SHFLEHMFFKGTSTKSAREIAESFDRIGGQVNAFTSKEYTCYYAKVLDEHANYALDVL ADMFFHSTFDENELKKEKNVVYEEIKMYEDAPDDIVHDLLSKATYGNHSLGYPILGTE ETLASFNGDSLRQYMHDYYTPDRVVISVAGNISDSFIKDVEKWFGSYEAKGKATGLEK PEFHTEKLTRKKETEQAHLCLGFKGLEVGHERIYDLIVLNNVLGGSMSSRLFQDVRED KGLAYSVYSYHSSYEDSGMLTIYGGTGANQLQQLSETIQETLATLKRDGITSKELENS KEQMKGSLMLSLESTNSKMSRNGKNELLLGKHKTLDEIINELNAVNLERVNGLARQLF TEDYALALISPSGNMPS*" gene 1742617..1743846 /gene="mlpA" /locus_tag="BSU_16710" /old_locus_tag="BSU16710" downshifts 1743835 /Source="Nicolas_upshifts" /id="D903" /incds=0 /nref=140 /ntot=219 /MaxReadThrough="1.31218" /MaxDrop="4.84427" /score="15.1952611" /energy="-12.6" /TU="NA" /idTUdmin="U1336" /TUdmin=0 /isTUend="TRUE" promotor_-35 1743875..1743880 /Source="Nicolas_upshift_promotors" /id="U1340" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1150 /SigmaFactorBS="gcaatatgccgtcttaaaaaggaaagcctgccccataatgga gcaGGCATTttttaatccctttcaTCATACATAGTACAAGGGGgtgacagacatgcgg c" /listShort="ymxH" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 1743890 /Source="Nicolas_upshifts" /id="U1340" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1150 /SigmaFactorBS="gcaatatgccgtcttaaaaaggaaagcctgccccataatgga gcaGGCATTttttaatccctttcaTCATACATAGTACAAGGGGgtgacagacatgcgg c" /listShort="ymxH" /GFF_Attribute="listLong" promotor_-10 1743896..1743914 /Source="Nicolas_upshift_promotors" /id="U1340" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1150 /SigmaFactorBS="gcaatatgccgtcttaaaaaggaaagcctgccccataatgga gcaGGCATTttttaatccctttcaTCATACATAGTACAAGGGGgtgacagacatgcgg c" /listShort="ymxH" /GFF_Attribute="listLong" /label="promotor_-10" CDS 1743924..1744181 /gene="ymxH" /locus_tag="BSU_16720" /old_locus_tag="BSU16720" /experiment="publication(s) with functional evidences, PMID:23396918" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 23396918; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="PRC barrel protein involved in sporulation" /protein_id="NP_389554.1" /db_xref="EnsemblGenomes-Gn:BSU16720" /db_xref="EnsemblGenomes-Tr:CAB13545" /db_xref="GOA:Q04811" /db_xref="InterPro:IPR011033" /db_xref="InterPro:IPR014238" /db_xref="InterPro:IPR027275" /db_xref="SubtiList:BG10780" /db_xref="UniProtKB/Swiss-Prot:Q04811" /translation="MRLSELSGKEIVDIKRAERLGVLGQTDLEINEQDGQITALLIPT VKWFGLRKQGHDIRVPWHHIQKIGSDMIILDVPEEMPPRQE*" gene 1743924..1744181 /gene="ymxH" /locus_tag="BSU_16720" /old_locus_tag="BSU16720" S_feature 1744182..1744236 /Source="Nicolas_S_feature" /locus_tag="new_1744182_1744236" /HighExp="S4, S3, S5, S6, S8, S7, B36, BT, LoTm, B60" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="NA" /TUshortPSig="NA" /TUlongSig="NA" /TUlongPSig="NA" /label="S597" downshifts 1744209 /Source="Nicolas_upshifts" /id="D904" /incds=0 /nref=41 /ntot=56 /MaxReadThrough="0.534319999999999" /MaxDrop="6.36032" /score="29.434739" /energy="-11.7" /TU="NA" /idTUdmin="U1340" /TUdmin=0 /isTUend="TRUE" promotor_-35 1744278..1744287 /Source="Nicolas_upshift_promotors" /id="U1341" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=1299 /SigmaFactorBS="ccggagccgatgtttttttatatggaaaaagcgcatcttttA TATTCACCGgtatttccttttgATCATAAGATGAAGGGGAGCttaacaactagagatc c" /listShort="S598, spoVFA, spoVFB, S599, asd, S600, dapG, dapA" /listLong="rnjB" /label="promotor_-35" S_feature 1744297..1744366 /Source="Nicolas_S_feature" /locus_tag="new_1744297_1744366" /HighExp="S6, S8, S7, BT, B36, S5, G/S, Pyr, B60, nit" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigK" /TUshortPSig="0.997" /TUlongSig="NA" /TUlongPSig="NA" /label="S598" upshifts 1744297 /Source="Nicolas_upshifts" /id="U1341" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=1299 /SigmaFactorBS="ccggagccgatgtttttttatatggaaaaagcgcatcttttA TATTCACCGgtatttccttttgATCATAAGATGAAGGGGAGCttaacaactagagatc c" /listShort="S598, spoVFA, spoVFB, S599, asd, S600, dapG, dapA" /listLong="rnjB" promotor_-10 1744301..1744320 /Source="Nicolas_upshift_promotors" /id="U1341" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=1299 /SigmaFactorBS="ccggagccgatgtttttttatatggaaaaagcgcatcttttA TATTCACCGgtatttccttttgATCATAAGATGAAGGGGAGCttaacaactagagatc c" /listShort="S598, spoVFA, spoVFB, S599, asd, S600, dapG, dapA" /listLong="rnjB" /label="promotor_-10" CDS 1744367..1745260 /gene="spoVFA" /locus_tag="BSU_16730" /old_locus_tag="BSU16730" /EC_number="1.3.1.-" /function="16.2: Construct biomass (Anabolism)" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:8098035, 8345520, 16707666, 25402593" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8098035, 8345520, 16707666, 25402593; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="spore dipicolinate synthase subunit A" /protein_id="NP_389555.1" /db_xref="EnsemblGenomes-Gn:BSU16730" /db_xref="EnsemblGenomes-Tr:CAB13546" /db_xref="GOA:Q04809" /db_xref="InterPro:IPR007698" /db_xref="InterPro:IPR014215" /db_xref="InterPro:IPR031629" /db_xref="InterPro:IPR036291" /db_xref="PDB:2RIR" /db_xref="SubtiList:BG10781" /db_xref="UniProtKB/Swiss-Prot:Q04809" /translation="MLTGLKIAVIGGDARQLEIIRKLTEQQADIYLVGFDQLDHGFTG AVKCNIDEIPFQQIDSIILPVSATTGEGVVSTVFSNEEVVLKQDHLDRTPAHCVIFSG ISNAYLENIAAQAKRKLVKLFERDDIAIYNSIPTVEGTIMLAIQHTDYTIHGSQVAVL GLGRTGMTIARTFAALGANVKVGARSSAHLARITEMGLVPFHTDELKEHVKDIDICIN TIPSMILNQTVLSSMTPKTLILDLASRPGGTDFKYAEKQGIKALLAPGLPGIVAPKTA GQILANVLSKLLAEIQAEEGK*" gene 1744367..1745260 /gene="spoVFA" /locus_tag="BSU_16730" /old_locus_tag="BSU16730" CDS 1745263..1745865 /gene="spoVFB" /locus_tag="BSU_16740" /old_locus_tag="BSU16740" /function="16.8: Protect" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:8098035, 8345520, 16707666, 25402593" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8098035, 8345520, 16707666, 25402593; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="spore dipicolinate synthase subunit B" /protein_id="NP_389556.1" /db_xref="EnsemblGenomes-Gn:BSU16740" /db_xref="EnsemblGenomes-Tr:CAB13547" /db_xref="GOA:Q04810" /db_xref="InterPro:IPR003382" /db_xref="InterPro:IPR014214" /db_xref="InterPro:IPR036551" /db_xref="SubtiList:BG10782" /db_xref="UniProtKB/Swiss-Prot:Q04810" /translation="MSSLKGKRIGFGLTGSHCTYEAVFPQIEELVNEGAEVRPVVTFN VKSTNTRFGEGAEWVKKIEDLTGYEAIDSIVKAEPLGPKLPLDCMVIAPLTGNSMSKL ANAMTDSPVLMAAKATIRNNRPVVLGISTNDALGLNGTNLMRLMSTKNIFFIPFGQDD PFKKPNSMVAKMDLLPQTIEKALMHQQLQPILVENYQGND*" gene 1745263..1745865 /gene="spoVFB" /locus_tag="BSU_16740" /old_locus_tag="BSU16740" misc_feature 1745919..1745938 /Source="Nicolas_upshift_promotors" /id="U1342" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.762237762237762" /psig="0.781218781218781" /xcortree=1233 /SigmaFactorBS="tgactaaatttacagaaaatctttcccaaactaaaaaattcg gtcatcacccgcatattcTATGGTAAAATAAAACGTAAaatcatagtcaaatcaattc a" /listShort="S599, asd, S600, dapG, dapA, rnjB, tepA, ylzJ" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" S_feature 1745919..1745990 /Source="Nicolas_S_feature" /locus_tag="new_1745919_1745990" /HighExp="S6, S7, S8, C90, S5, BT, MG 45, MG 5, SMM, B36" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigK" /TUshortPSig="0.781, 0.997" /TUlongSig="NA" /TUlongPSig="NA" /label="S599" upshifts 1745919 /Source="Nicolas_upshifts" /id="U1342" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.762237762237762" /psig="0.781218781218781" /xcortree=1233 /SigmaFactorBS="tgactaaatttacagaaaatctttcccaaactaaaaaattcg gtcatcacccgcatattcTATGGTAAAATAAAACGTAAaatcatagtcaaatcaattc a" /listShort="S599, asd, S600, dapG, dapA, rnjB, tepA, ylzJ" /GFF_Attribute="listLong" CDS 1745991..1747031 /gene="asd" /locus_tag="BSU_16750" /old_locus_tag="BSU16750" /EC_number="1.2.1.11" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:8098035, 12682299, 25355936, 25393291" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8098035, 12682299, 25355936, 25393291; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="aspartate-semialdehyde dehydrogenase" /protein_id="NP_389557.1" /db_xref="EnsemblGenomes-Gn:BSU16750" /db_xref="EnsemblGenomes-Tr:CAB13548" /db_xref="GOA:Q04797" /db_xref="InterPro:IPR000319" /db_xref="InterPro:IPR000534" /db_xref="InterPro:IPR005986" /db_xref="InterPro:IPR012080" /db_xref="InterPro:IPR012280" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG10783" /db_xref="UniProtKB/Swiss-Prot:Q04797" /translation="MGRGLHVAVVGATGAVGQQMLKTLEDRNFEMDTLTLLSSKRSAG TKVTFKGQELTVQEASPESFEGVNIALFSAGGSVSQALAPEAVKRGAIVIDNTSAFRM DENTPLVVPEVNEADLHEHNGIIANPNCSTIQMVAALEPIRKAYGLNKVIVSTYQAVS GAGNEAVKELYSQTQAILNKEEIEPEIMPVKGDKKHYQIAFNAIPQIDKFQDNGYTFE EMKMINETKKIMHMPDLQVAATCVRLPIQTGHSESVYIEIDRDDATVEDIKNLLKEAP GVTLQDDPSQQLYPMPADAVGKNDVFVGRIRKDLDRANGFHLWVVSDNLLKGAAWNSV QIAESLKKLNLV*" gene 1745991..1747031 /gene="asd" /locus_tag="BSU_16750" /old_locus_tag="BSU16750" S_feature 1747032..1747122 /Source="Nicolas_S_feature" /locus_tag="new_1747032_1747122" /HighExp="S7, S6, S8, LBGtran, GM 120, dia15, Heat, LBGstat, GM 90, MG 120" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigK" /TUshortPSig="0.781, 0.997" /TUlongSig="NA" /TUlongPSig="NA" /label="S600" CDS 1747123..1748337 /gene="dapG" /locus_tag="BSU_16760" /old_locus_tag="BSU16760" /EC_number="2.7.2.4" /function="16.2: Construct biomass (Anabolism)" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:1906928, 8098035" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1906928, 8098035; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="aspartokinase I (alpha and beta subunits)" /protein_id="NP_389558.2" /db_xref="EnsemblGenomes-Gn:BSU16760" /db_xref="EnsemblGenomes-Tr:CAB13549" /db_xref="GOA:Q04795" /db_xref="InterPro:IPR001048" /db_xref="InterPro:IPR001341" /db_xref="InterPro:IPR002912" /db_xref="InterPro:IPR005260" /db_xref="InterPro:IPR018042" /db_xref="InterPro:IPR027795" /db_xref="InterPro:IPR036393" /db_xref="SubtiList:BG10784" /db_xref="UniProtKB/Swiss-Prot:Q04795" /translation="MKIIVQKFGGTSVKDDKGRKLALGHIKEAISEGYKVVVVVSAMG RKGDPYATDSLLGLLYGDQSAISPREQDLLLSCGETISSVVFTSMLLDNGVKAAALTG AQAGFLTNDQHTNAKIIEMKPERLFSVLANHDAVVVAGFQGATEKGDTTTIGRGGSDT SAAALGAAVDAEYIDIFTDVEGVMTADPRVVENAKPLPVVTYTEICNLAYQGAKVISP RAVEIAMQAKVPIRVRSTYSNDKGTLVTSHHSSKVGSDVFERLITGIAHVKDVTQFKV PAKIGQYNVQTEVFKAMANAGISVDFFNITPSEIVYTVAGNKTETAQRILMDMGYDPM VTRNCAKVSAVGAGIMGVPGVTSKIVSALSEKEIPILQSADSHTTIWVLVHEADMVPA VNALHEVFELSK*" gene 1747123..1748337 /gene="dapG" /locus_tag="BSU_16760" /old_locus_tag="BSU16760" CDS 1748368..1749240 /gene="dapA" /locus_tag="BSU_16770" /old_locus_tag="BSU16770" /EC_number="4.3.3.7" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:8098035, 9298659" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8098035, 9298659; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="4-hydroxy-tetrahydrodipicolinate synthase" /protein_id="NP_389559.1" /db_xref="EnsemblGenomes-Gn:BSU16770" /db_xref="EnsemblGenomes-Tr:CAB13550" /db_xref="GOA:Q04796" /db_xref="InterPro:IPR002220" /db_xref="InterPro:IPR005263" /db_xref="InterPro:IPR013785" /db_xref="InterPro:IPR020624" /db_xref="InterPro:IPR020625" /db_xref="SubtiList:BG10785" /db_xref="UniProtKB/Swiss-Prot:Q04796" /translation="MNFGNVSTAMITPFDNKGNVDFQKLSTLIDYLLKNGTDSLVVAG TTGESPTLSTEEKIALFEYTVKEVNGRVPVIAGTGSNNTKDSIKLTKKAEEAGVDAVM LVTPYYNKPSQEGMYQHFKAIAAETSLPVMLYNVPGRTVASLAPETTIRLAADIPNVV AIKEASGDLEAITKIIAETPEDFYVYSGDDALTLPILSVGGRGVVSVASHIAGTDMQQ MIKNYTNGQTANAALIHQKLLPIMKELFKAPNPAPVKTALQLRGLDVGSVRLPLVPLT EDERLSLSSTISEL*" gene 1748368..1749240 /gene="dapA" /locus_tag="BSU_16770" /old_locus_tag="BSU16770" S_feature complement(1748711..1749895) /Source="Nicolas_S_feature" /locus_tag="new_1748711_1749895_c" /HighExp="S8, S6, S4, S5, S7, S3, LoTm, T5.0H, BT, C30" /AntisenseName="dapA" /AntisenseCor="0.13444126275526899" /AntisenseRegPval="-1.6" /CDS_PredictionProba="NA" /TUshortSig="SigEF" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S601" downshifts 1749247 /Source="Nicolas_upshifts" /id="D905" /incds=0 /nref=17 /ntot=99 /MaxReadThrough="6.0497" /MaxDrop="5.05122" /score="24.080775" /energy="-11.7" /TU="U1342" /idTUdmin="U1341" /TUdmin=0 /isTUend="TRUE" promotor_-35 1749340..1749343 /Source="Nicolas_upshift_promotors" /id="U1343" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.862137862137862" /psig=1 /xcortree=2241 /SigmaFactorBS="cgtttcttttacatattggttttccctaaaccttctgcttta tCTTGttttctaaatttactTTCAGTTATAATAGGAACAAgtgatgatggacgggtat g" /listShort="rnjB" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 1749357 /Source="Nicolas_upshifts" /id="U1343" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.862137862137862" /psig=1 /xcortree=2241 /SigmaFactorBS="cgtttcttttacatattggttttccctaaaccttctgcttta tCTTGttttctaaatttactTTCAGTTATAATAGGAACAAgtgatgatggacgggtat g" /listShort="rnjB" /GFF_Attribute="listLong" promotor_-10 1749359..1749378 /Source="Nicolas_upshift_promotors" /id="U1343" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.862137862137862" /psig=1 /xcortree=2241 /SigmaFactorBS="cgtttcttttacatattggttttccctaaaccttctgcttta tCTTGttttctaaatttactTTCAGTTATAATAGGAACAAgtgatgatggacgggtat g" /listShort="rnjB" /GFF_Attribute="listLong" /label="promotor_-10" CDS 1749418..1751085 /gene="rnjB" /locus_tag="BSU_16780" /old_locus_tag="BSU16780" /EC_number="3.1.-.-" /function="16.6: Maintain" /function="16.11: Scavenge (Catabolism)" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:15831787, 18713320, 20025672, 20729365, 24187087, 26296725, 28384222" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15831787, 18713320, 20025672, 20729365, 24187087, 26296725, 28384222; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="dual activity 5' exo-and endoribonuclease J2" /protein_id="NP_389560.2" /db_xref="EnsemblGenomes-Gn:BSU16780" /db_xref="EnsemblGenomes-Tr:CAB13551" /db_xref="GOA:O31760" /db_xref="InterPro:IPR001279" /db_xref="InterPro:IPR004613" /db_xref="InterPro:IPR011108" /db_xref="InterPro:IPR030854" /db_xref="InterPro:IPR036866" /db_xref="SubtiList:BG13422" /db_xref="UniProtKB/Swiss-Prot:O31760" /translation="MKKKNTENVRIIALGGVGEIGKNLYVIEIDSDIFVVDAGLMHPE NEMLGIDVVIPDISYLIERADRVKAIFLTHGHDENIGGVFYLLNKLSVPVYGTKLTLA LLREKLKQYGHNRKTDLREIHSKSVITFESTKVSFFRTIHSIPDSVGVSFKTSLGSIV CTGDFKFDQTPALNQTCDIGEIAKIGNSGVLALLSDSANAERPGYTPSEAAVSGEISD ALYNSQNRVIIAVFASNINRIQQVIHAAAQNGRKIAVAGKNLQSVLQLARKLGYIEAD DELFISVQDVKKYPKREVAIITAGSQGEPLAALTRMANKAHKQLNIEEGDTVVIASTP IPGQELIYSKTVDLLARAGAQVIFAQKRVHVSGHGSQEELKLMINLLKPKYLIPVNGE YRMQKAHSKIAEETGMKRSDIFLIEKGDVVEFRGQNVKIGDKVPYGNILIDGLGVGDI GNIVLRDRRLLSQDGILIVVITLDKQKKHLVSGPEIITRGFVYVRESEGLIVQATELV RSIVTEATETSNVEWSTLKQAMRDALNQFLYEKTKRKPMIIPIIMEV*" gene 1749418..1751085 /gene="rnjB" /locus_tag="BSU_16780" /old_locus_tag="BSU16780" promotor_-10 complement(1749882..1749900) /Source="Nicolas_upshift_promotors" /id="U1344" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1085 /SigmaFactorBS="tcgccaatgtcgcacgtctgattaagtgcaggtgtttgGTCA AAtttgaagtctcccgtGCATACAATAGATCCAAGTgatgttttaaagctcacaccta c" /listShort="S601" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1749899) /Source="Nicolas_upshifts" /id="U1344" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1085 /SigmaFactorBS="tcgccaatgtcgcacgtctgattaagtgcaggtgtttgGTCA AAtttgaagtctcccgtGCATACAATAGATCCAAGTgatgttttaaagctcacaccta c" /listShort="S601" /GFF_Attribute="listLong" promotor_-35 complement(1749916..1749921) /Source="Nicolas_upshift_promotors" /id="U1344" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1085 /SigmaFactorBS="tcgccaatgtcgcacgtctgattaagtgcaggtgtttgGTCA AAtttgaagtctcccgtGCATACAATAGATCCAAGTgatgttttaaagctcacaccta c" /listShort="S601" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 1751073 /Source="Nicolas_upshifts" /id="D906" /incds=0 /nref=227 /ntot=263 /MaxReadThrough="4.0072" /MaxDrop="6.75416" /score="24.080775" /energy="-11.7" /TU="U1342" /idTUdmin="U1343" /TUdmin=0 /isTUend="TRUE" promotor_-35 1751140..1751146 /Source="Nicolas_upshift_promotors" /id="U1345" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.995004995004995" /psig="0.995004995004995" /xcortree=917 /SigmaFactorBS="cggagctgctccggtctttattttttgtccttcaagccgGGA TTGAatgaagtatctttGTTCATAATACAaagagaaactcggaaaggatgaaagcgag a" /listShort="tepA, ylzJ, spoIIIE, S602" /listLong="ymfC" /label="promotor_-35" promotor_-10 1751160..1751171 /Source="Nicolas_upshift_promotors" /id="U1345" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.995004995004995" /psig="0.995004995004995" /xcortree=917 /SigmaFactorBS="cggagctgctccggtctttattttttgtccttcaagccgGGA TTGAatgaagtatctttGTTCATAATACAaagagaaactcggaaaggatgaaagcgag a" /listShort="tepA, ylzJ, spoIIIE, S602" /listLong="ymfC" /label="promotor_-10" upshifts 1751161 /Source="Nicolas_upshifts" /id="U1345" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.995004995004995" /psig="0.995004995004995" /xcortree=917 /SigmaFactorBS="cggagctgctccggtctttattttttgtccttcaagccgGGA TTGAatgaagtatctttGTTCATAATACAaagagaaactcggaaaggatgaaagcgag a" /listShort="tepA, ylzJ, spoIIIE, S602" /listLong="ymfC" CDS 1751201..1751938 /gene="tepA" /locus_tag="BSU_16790" /old_locus_tag="BSU16790" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:10455123, 15189290, 23927687" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10455123, 15189290, 23927687; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="protein export-enhancing protease (spore outgrowth)" /protein_id="NP_389561.3" /db_xref="EnsemblGenomes-Gn:BSU16790" /db_xref="EnsemblGenomes-Tr:CAB13552" /db_xref="GOA:Q99171" /db_xref="InterPro:IPR023562" /db_xref="InterPro:IPR029045" /db_xref="SubtiList:BG11055" /db_xref="UniProtKB/Swiss-Prot:Q99171" /translation="MDHRMENTEEERPEKNDAKDSIMNKIQQLGETTLPQLPQDTNIH CLTIIGQIEGHVQLPPQNKTTKYEHVIPQIVAIEQNPKIEGLLIILNTVGGDVEAGLA IAEMLASLSKPTVSIVLGGGHSIGVPIAVSCDYSYIAETATMTIHPVRLTGLVIGVPQ TFEYLDKMQERVVKFVTSHSNITEEKFKELMFSKGNLTRDIGTNVVGKDAVKYGLIDH AGGVGQAINKLNELIDEARKEEGRMIQ*" gene 1751201..1751938 /gene="tepA" /locus_tag="BSU_16790" /old_locus_tag="BSU16790" CDS 1751935..1752147 /gene="tepJ" /locus_tag="BSU_16799" /old_locus_tag="BSU16799" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:23927687" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 23927687; Product type r: regulator" /codon_start=1 /transl_table=11 /product="modulator of TepA activity (spore outgrowth)" /protein_id="YP_003097729.1" /db_xref="EnsemblGenomes-Gn:BSU16799" /db_xref="EnsemblGenomes-Tr:CAX52620" /db_xref="InterPro:IPR025619" /db_xref="UniProtKB/Swiss-Prot:C0H413" /translation="MILYTVMPQEIVFAEQNQETSAHEQIEYKGVPLLVEMKGNEAEV IQIMSTNPMHFLHPDISPGQKLKLNV*" gene 1751935..1752147 /gene="tepJ" /locus_tag="BSU_16799" /old_locus_tag="BSU16799" misc_feature 1752175..1752194 /Source="Nicolas_upshift_promotors" /id="U1346" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.997002997002997" /psig="0.999000999001" /xcortree=2128 /SigmaFactorBS="gctgaaattaaacgtataagaatccaacccttttttaagggc aaaaTATGCTATAATAGGGGAATCctacagaaaaaacgcagcctgtaaacggctgctt t" /listShort="spoIIIE, S602, ymfC" /listLong="ymfD" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 1752189 /Source="Nicolas_upshifts" /id="U1346" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.997002997002997" /psig="0.999000999001" /xcortree=2128 /SigmaFactorBS="gctgaaattaaacgtataagaatccaacccttttttaagggc aaaaTATGCTATAATAGGGGAATCctacagaaaaaacgcagcctgtaaacggctgctt t" /listShort="spoIIIE, S602, ymfC" /listLong="ymfD" CDS 1752278..1754641 /gene="spoIIIE" /locus_tag="BSU_16800" /old_locus_tag="BSU16800" /function="16.13: Shape" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 11062134, 11778051, 12618465, 16430687, 17139259, 17322320, 18160039, 24297254, 24769697, 26452092; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="spore DNA directional translocase (motor ATPase)" /protein_id="NP_389562.3" /db_xref="EnsemblGenomes-Gn:BSU16800" /db_xref="EnsemblGenomes-Tr:CAB13553" /db_xref="GOA:P21458" /db_xref="InterPro:IPR002543" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR018541" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG10763" /db_xref="UniProtKB/Swiss-Prot:P21458" /translation="MAKKKRKSRKKQAKQLNIKYELNGLLCIAISIIAILQLGVVGQT FIYLFRFFAGEWFILCLLGLLVLGVSLFWKKKTPSLLTRRKAGLYCIIASILLLSHVQ LFKNLTHKGSIESASVVRNTWELFLMDMNGSSASPDLGGGMIGALLFAASHFLFASTG SQIMAIVMILIGMILVTGRSLQETLKKWMSPIGRFIKEQWLAFIDDMKSFKSNMQSSK KTKAPSKKQKPARKKQQMEPEPPDEEGDYETVSPLIHSEPIISSFSDRNEEEESPVIE KRAEPVSKPLQDIQPETGDQETVSAPPMTFTELENKDYEMPSLDLLADPKHTGQQADK KNIYENARKLERTFQSFGVKAKVTQVHLGPAVTKYEVYPDVGVKVSKIVNLSDDLALA LAAKDIRIEAPIPGKSAIGIEVPNAEVAMVSLKEVLESKLNDRPDAKLLIGLGRNISG EAVLAELNKMPHLLVAGATGSGKSVCVNGIITSILMRAKPHEVKMMMIDPKMVELNVY NGIPHLLAPVVTDPKKASQALKKVVNEMERRYELFSHTGTRNIEGYNDYIKRANNEEG AKQPELPYIVVIVDELADLMMVASSDVEDSITRLSQMARAAGIHLIIATQRPSVDVIT GVIKANIPSRIAFSVSSQTDSRTILDMGGAEKLLGRGDMLFLPVGANKPVRVQGAFLS DDEVEKVVDHVITQQKAQYQEEMIPEETTETHSEVTDELYDEAVELIVGMQTASVSML QRRFRIGYTRAARLIDAMEERGVVGPYEGSKPREVLLSKEKYDELSS*" gene 1752278..1754641 /gene="spoIIIE" /locus_tag="BSU_16800" /old_locus_tag="BSU16800" S_feature 1754642..1754742 /Source="Nicolas_S_feature" /locus_tag="new_1754642_1754742" /HighExp="Cold, C30, G135, Lbstat, BC, G180, G150, S8, LoTm, S6" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.109246" /TUshortSig="SigA, SigGF" /TUshortPSig="0.999, 0.995" /TUlongSig="NA" /TUlongPSig="NA" /label="S602" promotor_-35 1754703..1754710 /Source="Nicolas_upshift_promotors" /id="U1347" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.742257742257742" /psig="0.98901098901099" /xcortree=3004 /SigmaFactorBS="atgtaaactgatcacctttcTATTTATTttttcgacaaaaca TGATATAGTTGTCCCAATTGttcaataatttttatcgaaagtggtttacggaggggaa a" /listShort="ymfC, ymfD" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1754725..1754744 /Source="Nicolas_upshift_promotors" /id="U1347" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.742257742257742" /psig="0.98901098901099" /xcortree=3004 /SigmaFactorBS="atgtaaactgatcacctttcTATTTATTttttcgacaaaaca TGATATAGTTGTCCCAATTGttcaataatttttatcgaaagtggtttacggaggggaa a" /listShort="ymfC, ymfD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1754743 /Source="Nicolas_upshifts" /id="U1347" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.742257742257742" /psig="0.98901098901099" /xcortree=3004 /SigmaFactorBS="atgtaaactgatcacctttcTATTTATTttttcgacaaaaca TGATATAGTTGTCCCAATTGttcaataatttttatcgaaagtggtttacggaggggaa a" /listShort="ymfC, ymfD" /GFF_Attribute="listLong" CDS 1754785..1755510 /gene="ymfC" /locus_tag="BSU_16810" /old_locus_tag="BSU16810" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative transcriptional regulator (GntR family,possibly involved in biofilm formation)" /protein_id="NP_389563.1" /db_xref="EnsemblGenomes-Gn:BSU16810" /db_xref="EnsemblGenomes-Tr:CAB13554" /db_xref="GOA:O31761" /db_xref="InterPro:IPR000524" /db_xref="InterPro:IPR011663" /db_xref="InterPro:IPR028978" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG13423" /db_xref="UniProtKB/Swiss-Prot:O31761" /translation="MSTKADNRHLYLKVIERIKEDIKNGIYTEKEKLPSEFELSKKLG VSRATLREALRILEEEHVIIRRHGVGTFVHSKPLFLSGIEQLNSVTKMIEQANMTPGT IFLSSQVLMPSEDDTKRFHLAEGQELFYLERVRTADGQPIVYCIDKIPMNILPNSFSH QQESMFDLLEKNSGSVISYAVTDIEPIGYHDTISPVLECDPETALLLLKQTHYDQHDK PVLYSLNYFRADKFRFHVLRKRF*" gene 1754785..1755510 /gene="ymfC" /locus_tag="BSU_16810" /old_locus_tag="BSU16810" downshifts 1755497 /Source="Nicolas_upshifts" /id="D907" /incds=0 /nref=135 /ntot=256 /MaxReadThrough="4.863" /MaxDrop="4.01593" /score="16.3235883" /energy="-7.2" /TU="U1346,U1347" /idTUdmin="U1346" /TUdmin="-88" /isTUend="FALSE" promotor_-35 1755566..1755572 /Source="Nicolas_upshift_promotors" /id="U1348" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=912 /SigmaFactorBS="atgtgtctgtttttttatttgcactgattcatgtttctttgT ACATACtttcattccggttaACGCAATATATAagggatgacaagaaagtgaatgggtg a" /listShort="ymfD" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 1755585 /Source="Nicolas_upshifts" /id="U1348" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=912 /SigmaFactorBS="atgtgtctgtttttttatttgcactgattcatgtttctttgT ACATACtttcattccggttaACGCAATATATAagggatgacaagaaagtgaatgggtg a" /listShort="ymfD" /GFF_Attribute="listLong" promotor_-10 1755587..1755598 /Source="Nicolas_upshift_promotors" /id="U1348" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=912 /SigmaFactorBS="atgtgtctgtttttttatttgcactgattcatgtttctttgT ACATACtttcattccggttaACGCAATATATAagggatgacaagaaagtgaatgggtg a" /listShort="ymfD" /GFF_Attribute="listLong" /label="promotor_-10" CDS 1755649..1756857 /gene="bcbE" /locus_tag="BSU_16825" /old_locus_tag="BSU16825" /function="7: Transport and binding proteins" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:15849754, 16850406, 18502870, 27375568" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15849754, 16850406, 18502870, 27375568; Product type t: transporter" /codon_start=1 /transl_table=11 /product="bacillibactin exporter" /protein_id="NP_389564.2" /db_xref="EnsemblGenomes-Gn:BSU16825" /db_xref="EnsemblGenomes-Tr:CAB13555" /db_xref="GOA:O31762" /db_xref="InterPro:IPR001958" /db_xref="InterPro:IPR011701" /db_xref="InterPro:IPR020846" /db_xref="InterPro:IPR036259" /db_xref="SubtiList:BG13424" /db_xref="UniProtKB/Swiss-Prot:O31762" /translation="MKNIIALSSVPLVMTLGNSMLIPVLPMMEKKLSVTSFQVSLIIT VYSVVAIICIPIAGYLSDRFGRKKILLPCLLIAGLGGAVAAFASTYMKNPYAMILAGR VLQGIGSAGAAPIVMPFIGDLFKGDDEKVSAGLGDIETANTSGKVLSPILGALLASWY WFVPFWFIPFFCLISFLLVLFLVAKPEEDEDAPAVSEFIKSVKKIFKQDGRWLYTVFI IGCVIMFLLFGVLFYLSDTLENKYAIDGVAKGGLLAIPLLFLSTSSFIAGKKIGKDKG RMKFCVVTGMILLTLSFIALWWNHSFYFLFVFLSFGGIGIGMALPALDALITEGIESE QCGTISSFYNSMRFIGVALGPPVFAALMSNANWIIFILSAFCSIVSLFLVLFTVDAKK SEEEKNLGTV*" gene 1755649..1756857 /gene="bcbE" /locus_tag="BSU_16825" /old_locus_tag="BSU16825" downshifts 1756815 /Source="Nicolas_upshifts" /id="D908" /incds=0 /nref=1 /ntot=32 /MaxReadThrough="1.34389" /MaxDrop="3.00655" /score="5.64651968" /energy="-6.7" /TU="NA" /idTUdmin="U1348" /TUdmin=0 /isTUend="TRUE" promotor_-35 1756926..1756933 /Source="Nicolas_upshift_promotors" /id="U1349" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.5994005994006" /psig="0.987012987012987" /xcortree=1918 /SigmaFactorBS="cagcatgcggaggttattGTTTCCTTataaatcctacaGTTG CTATAATTACATGAAAgagtgtttctgcggatgctgaaaattggtcataatacatact a" /listShort="ymfF, ymfH, S603, ymfI, ymfJ, ymfK, ymfK, ymfM" /listLong="pgsA, cinA, S604, recA, S605, pbpX, S606, S607, ymdA, ymdB, S608, spoVS" /label="promotor_-35" promotor_-10 1756946..1756965 /Source="Nicolas_upshift_promotors" /id="U1349" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.5994005994006" /psig="0.987012987012987" /xcortree=1918 /SigmaFactorBS="cagcatgcggaggttattGTTTCCTTataaatcctacaGTTG CTATAATTACATGAAAgagtgtttctgcggatgctgaaaattggtcataatacatact a" /listShort="ymfF, ymfH, S603, ymfI, ymfJ, ymfK, ymfK, ymfM" /listLong="pgsA, cinA, S604, recA, S605, pbpX, S606, S607, ymdA, ymdB, S608, spoVS" /label="promotor_-10" upshifts 1756968 /Source="Nicolas_upshifts" /id="U1349" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.5994005994006" /psig="0.987012987012987" /xcortree=1918 /SigmaFactorBS="cagcatgcggaggttattGTTTCCTTataaatcctacaGTTG CTATAATTACATGAAAgagtgtttctgcggatgctgaaaattggtcataatacatact a" /listShort="ymfF, ymfH, S603, ymfI, ymfJ, ymfK, ymfK, ymfM" /listLong="pgsA, cinA, S604, recA, S605, pbpX, S606, S607, ymdA, ymdB, S608, spoVS" promotor_-35 1756980..1756983 /Source="Nicolas_upshift_promotors" /id="U1350" /multdbtbs="-" /comp="M3" /sig="Sig-" /pcomp="0.430569430569431" /psig="0.430569430569431" /xcortree=811 /SigmaFactorBS="taattacatgaaagagtgtttctgcggATGCtgaaaattggt cataATACATACTAATTaagaaatgaacgaaggaggttccatatgtcatatgttaatg a" /listShort="ymfF, ymfH, S603, ymfI, ymfJ" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1756999..1757011 /Source="Nicolas_upshift_promotors" /id="U1350" /multdbtbs="-" /comp="M3" /sig="Sig-" /pcomp="0.430569430569431" /psig="0.430569430569431" /xcortree=811 /SigmaFactorBS="taattacatgaaagagtgtttctgcggATGCtgaaaattggt cataATACATACTAATTaagaaatgaacgaaggaggttccatatgtcatatgttaatg a" /listShort="ymfF, ymfH, S603, ymfI, ymfJ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1757013 /Source="Nicolas_upshifts" /id="U1350" /multdbtbs="-" /comp="M3" /sig="Sig-" /pcomp="0.430569430569431" /psig="0.430569430569431" /xcortree=811 /SigmaFactorBS="taattacatgaaagagtgtttctgcggATGCtgaaaattggt cataATACATACTAATTaagaaatgaacgaaggaggttccatatgtcatatgttaatg a" /listShort="ymfF, ymfH, S603, ymfI, ymfJ" /GFF_Attribute="listLong" CDS 1757037..1758317 /gene="ymfF" /locus_tag="BSU_16845" /old_locus_tag="BSU16845" /function="16.11: Scavenge (Catabolism)" /function="16.3: Control" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 22333191; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative metalloprotease" /protein_id="NP_389566.2" /db_xref="EnsemblGenomes-Gn:BSU16845" /db_xref="EnsemblGenomes-Tr:CAB13557" /db_xref="GOA:O31764" /db_xref="InterPro:IPR007863" /db_xref="InterPro:IPR011249" /db_xref="SubtiList:BG13426" /db_xref="UniProtKB/Swiss-Prot:O31764" /translation="MSYVNELKSKHGGLTAHIVKTEKFKTVSLIFKMLAPLTKDQVTK RALLPHVLLRGTKSHPKTAGLRSYLDELYGTSVSADLTKKGERHVITFRLEIPNEKYL KDQTPLLEKGLQLLAELVFSPALEGDAFQSQYVAQEKRTLKQRIQAVYDDKMRYSNLR LIQEMCKNDPYALHVNGEIDDVDDITAEQLYETYQSAIQKDQLDLYVVGDVDSNQVQS AIDKYFKTEERTLGMIENNHADEKVQPKEVIDEEDVKQGKLNIGYRTSITYTDQDYPA LQVFNGLFGGFSHSKLFINVREKASLAYYAASRIESFKGLLMVMSGIEVKNFEQAVSI IAEQFQAMKNGDFSEQDIAQTKAVIRNQVLETIDTAYGLSEFLYQQAAAQVEIPIEDF LANIENVTKEDIIKAGEKIQLDTTYFLKGTEGAS*" gene 1757037..1758317 /gene="ymfF" /locus_tag="BSU_16845" /old_locus_tag="BSU16845" CDS 1758314..1759600 /gene="ymfH" /locus_tag="BSU_16860" /old_locus_tag="BSU16860" /EC_number="3.4.24.-" /function="16.6: Maintain" /function="16.3: Control" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 22333191, 22720735; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative processing protease" /protein_id="NP_389568.2" /db_xref="EnsemblGenomes-Gn:BSU16860" /db_xref="EnsemblGenomes-Tr:CAB13559" /db_xref="GOA:O31766" /db_xref="InterPro:IPR007863" /db_xref="InterPro:IPR011249" /db_xref="InterPro:IPR011765" /db_xref="SubtiList:BG13428" /db_xref="UniProtKB/Swiss-Prot:O31766" /translation="MIKPIEYEQLQETLYHEKMSNGLDVYVLPKKGFNKTYAVFTTKY GSIDNRFVPLGKNEMVHVPDGIAHFLEHKLFEKADGDVFQDFSKQGASANAFTSFTRT AYLFSSTSNVERNLETLIDFVQDPYFTEKTVEKEKGIIGQEINMYDDNPDWRLYFGVI ENMYKEHPVRIDIAGTVESISHITKDLLYECYETFYHPSNMLLFIVGPVDPEAIISQV RENQGKKPYTDQPEIKREEVKEQEAVFRKEKEIKMNVQGPKCLVGLKSKNPFKLGKEL LKHELSMNLLLEALFGKSSAQYESLYEKGYIDETFSFDFTAEYGFGFAAIGGDTPEPD QLAEDISSMLLRAGELITAEKIELARKKKIGTFLKALNSPEYIANQFTRYAFLDMSLF DVVTVLEQITLEDVQNVIQEEIAADRLTVCKVVPKS*" gene 1758314..1759600 /gene="ymfH" /locus_tag="BSU_16860" /old_locus_tag="BSU16860" downshifts 1759450 /Source="Nicolas_upshifts" /id="D909" /incds=1 /nref=10 /ntot=159 /MaxReadThrough="5.673" /MaxDrop="3.16735" /score="1.51160893" /energy="-10.4" /TU="U1349,U1350" /idTUdmin="U1350" /TUdmin="-1256" /isTUend="FALSE" S_feature 1759601..1759654 /Source="Nicolas_S_feature" /locus_tag="new_1759601_1759654" /HighExp="Etha, dia15, H2O2, G135, G150, G180, Paraq, LBGexp, Oxctl, B36" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="Sig-, SigA" /TUshortPSig="0.431, 0.987" /TUlongSig="NA" /TUlongPSig="NA" /label="S603" CDS 1759655..1760383 /gene="efpI" /locus_tag="BSU_16870" /old_locus_tag="BSU16870" /EC_number="1.1.1.-" /function="16.2: Construct biomass (Anabolism)" /function="16.5: Explore" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:15066026, 28787546" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15066026, 28787546; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="EF-P-5 aminopentanone reductase (EF-P repair enzyme), NADPH-dependent" /protein_id="NP_389569.2" /db_xref="EnsemblGenomes-Gn:BSU16870" /db_xref="EnsemblGenomes-Tr:CAB13560" /db_xref="GOA:O31767" /db_xref="InterPro:IPR002347" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG13429" /db_xref="UniProtKB/Swiss-Prot:O31767" /translation="MNKTALITGASGGIGKSISETLAARGYNLLLHYNTNQNAAAELA EKLSQMFGVNAEILQADLSAQDGADKLTSSIVQPIDAIVLNSGRSHFGLITDVDNATV QEMVQLHVASPYMLTRNLLPGMIRNKSGAIVAVSSIWGETGASCEVLYSMAKGAQHSF VKGLAKELAPSGIRVNAVAPGAVDTNMMNQFTPAEKEEIADEIPIGRLARPQEIADAT AFLLSEKASYITGQILSVNGGWHC*" gene 1759655..1760383 /gene="efpI" /locus_tag="BSU_16870" /old_locus_tag="BSU16870" promotor_-35 1760399..1760405 /Source="Nicolas_upshift_promotors" /id="U1351" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=829 /SigmaFactorBS="tcggtgaatggcggctggcactgctgatccgaaaatattcgg TGTATAGtttcttttgcgaaGGACACAATAATcttgtaacttcacatgaaatggagga a" /listShort="ymfJ, ymfK, ymfK, ymfM" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 1760417 /Source="Nicolas_upshifts" /id="U1351" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=829 /SigmaFactorBS="tcggtgaatggcggctggcactgctgatccgaaaatattcgg TGTATAGtttcttttgcgaaGGACACAATAATcttgtaacttcacatgaaatggagga a" /listShort="ymfJ, ymfK, ymfK, ymfM" /GFF_Attribute="listLong" promotor_-10 1760419..1760430 /Source="Nicolas_upshift_promotors" /id="U1351" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=829 /SigmaFactorBS="tcggtgaatggcggctggcactgctgatccgaaaatattcgg TGTATAGtttcttttgcgaaGGACACAATAATcttgtaacttcacatgaaatggagga a" /listShort="ymfJ, ymfK, ymfK, ymfM" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1760430) /Source="Nicolas_upshifts" /id="U1352" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.945054945054945" /psig="0.050949050949051" /xcortree=702 /SigmaFactorBS="gctatcccagttttctaatactGACATgcttgtttCCTCCAT TTCATGTGaagttacaagattattgtgtccttcgcaaaagaaactatacaccgaatat t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 complement(1760441..1760455) /Source="Nicolas_upshift_promotors" /id="U1352" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.945054945054945" /psig="0.050949050949051" /xcortree=702 /SigmaFactorBS="gctatcccagttttctaatactGACATgcttgtttCCTCCAT TTCATGTGaagttacaagattattgtgtccttcgcaaaagaaactatacaccgaatat t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 complement(1760464..1760468) /Source="Nicolas_upshift_promotors" /id="U1352" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.945054945054945" /psig="0.050949050949051" /xcortree=702 /SigmaFactorBS="gctatcccagttttctaatactGACATgcttgtttCCTCCAT TTCATGTGaagttacaagattattgtgtccttcgcaaaagaaactatacaccgaatat t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" CDS 1760464..1760721 /gene="ymfJ" /locus_tag="BSU_16880" /old_locus_tag="BSU16880" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 17322312; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative enzyme" /protein_id="NP_389570.1" /db_xref="EnsemblGenomes-Gn:BSU16880" /db_xref="EnsemblGenomes-Tr:CAB13561" /db_xref="InterPro:IPR021637" /db_xref="InterPro:IPR024702" /db_xref="SubtiList:BG13430" /db_xref="UniProtKB/Swiss-Prot:O31768" /translation="MSVLENWDSWKNFLGDRLNYAQDKGMSQDTITDLATEIGSYLAN EVESKNEQEKVLADLWSVASKDEQHAIANMMVKLVENNSTH*" gene 1760464..1760721 /gene="ymfJ" /locus_tag="BSU_16880" /old_locus_tag="BSU16880" downshifts 1760706 /Source="Nicolas_upshifts" /id="D910" /incds=0 /nref=165 /ntot=250 /MaxReadThrough="4.58488" /MaxDrop="7.23574" /score="21.9507801" /energy="-8.7" /TU="U1349,U1351" /idTUdmin="U1350" /TUdmin=0 /isTUend="TRUE" downshifts complement(1760738) /Source="Nicolas_upshifts" /id="D911" /incds=0 /nref=2 /ntot=15 /MaxReadThrough="3.44398" /MaxDrop="3.96475" /score="-6.33040789" /energy="-7.2" /TU="NA" /idTUdmin="U1344" /TUdmin="-11987" /isTUend="FALSE" promotor_-35 1760779..1760782 /Source="Nicolas_upshift_promotors" /id="U1353" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.883116883116883" /psig="0.998001998001998" /xcortree=2284 /SigmaFactorBS="ttcctctcttttttatgttttcctcatcacagcaacattctt CTTTctaattagagaaaaATGCTTTATGATAAAGGAAGgtaaaattttgccacaatga a" /listShort="ymfK, ymfK, ymfM, pgsA, cinA, S604, recA" /listLong="S605, pbpX, S606, S607, ymdA, ymdB, S608, spoVS" /label="promotor_-35" promotor_-10 1760797..1760816 /Source="Nicolas_upshift_promotors" /id="U1353" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.883116883116883" /psig="0.998001998001998" /xcortree=2284 /SigmaFactorBS="ttcctctcttttttatgttttcctcatcacagcaacattctt CTTTctaattagagaaaaATGCTTTATGATAAAGGAAGgtaaaattttgccacaatga a" /listShort="ymfK, ymfK, ymfM, pgsA, cinA, S604, recA" /listLong="S605, pbpX, S606, S607, ymdA, ymdB, S608, spoVS" /label="promotor_-10" upshifts 1760797 /Source="Nicolas_upshifts" /id="U1353" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.883116883116883" /psig="0.998001998001998" /xcortree=2284 /SigmaFactorBS="ttcctctcttttttatgttttcctcatcacagcaacattctt CTTTctaattagagaaaaATGCTTTATGATAAAGGAAGgtaaaattttgccacaatga a" /listShort="ymfK, ymfK, ymfM, pgsA, cinA, S604, recA" /listLong="S605, pbpX, S606, S607, ymdA, ymdB, S608, spoVS" CDS 1760851..1761366 /gene="ymfKn" /locus_tag="BSU_16890" /old_locus_tag="BSU16890" /function="18: Unknown function" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /pseudo /codon_start=1 /transl_table=11 /product="conserved hypothetical protein with ACT domain; N-terminal part of YmfK" /db_xref="SubtiList:BG13431" /translation="MAKLEWYFEYEIQVNRPGLLGDISSLLGMLSINIVTINGVDLSR RGMLLRCRHIDQIKRLESILKTMETIKVTKLREPRLRDRLAVRHGRYIQRDADDKKTF RFERDELGLLVDFMAELFKKEGHKLIGIRGMPRVGKTESIVASSVCEQKVAVCVINLA EADDKKPADCR*" gene 1760851..1761366 /gene="ymfKn" /locus_tag="BSU_16890" /old_locus_tag="BSU16890" /pseudo CDS 1761302..1761640 /gene="ymfKc" /locus_tag="BSU_16900" /old_locus_tag="BSU16900" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /pseudo /codon_start=1 /transl_table=11 /product="conserved hypothetical protein with ACT domain; C-terminal part of YmfK" /db_xref="SubtiList:BG13432" /translation="RWLFVSSTLLKQTIRSQLIADEYSTENVFIVDGIVSTRRGSERH LQLVREIMRLPATKVVEHPDIFVQNTEYTLDDFDYIIELRNDPDEVITYEHAEEPQMF DQSGFSSFDF*" gene 1761302..1761640 /gene="ymfKc" /locus_tag="BSU_16900" /old_locus_tag="BSU16900" /pseudo CDS 1761707..1762573 /gene="rodZ" /locus_tag="BSU_16910" /old_locus_tag="BSU16910" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:12682299, 19164570, 22720735, 23879732, 27415800, 27818647" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12682299, 19164570, 22720735, 23879732, 27415800, 27818647; Product type f : factor" /codon_start=1 /transl_table=11 /product="cell shape determination factor" /protein_id="NP_389573.3" /db_xref="EnsemblGenomes-Gn:BSU16910" /db_xref="EnsemblGenomes-Tr:CAB13564" /db_xref="GOA:O31771" /db_xref="InterPro:IPR025194" /db_xref="SubtiList:BG13433" /db_xref="UniProtKB/Swiss-Prot:O31771" /translation="MSLDDLQAATKIQKRYLTALEEGNYDIIPGKFYVRAFIKQYAEA VGLDADQLFEEHKKDIPNTYHDDVSEKISGMNLQKEMPKPASKALELLPTILVILGVI VVIAIVYAIIQFANHKNSDDHNAASEKAITQSESKYEIPKDSTLKENQNNSSEKETDT KKETKENEDKKKENDSEKLEIKAAGTEGSLTTYEVSGADKIELELKASDSSWIRVRDE NSSSLKEGTLKKDETYKKDITDQKQVDIRTGYAPNLKIKINGKVLSYELDPKKVMAQT IKIVNKKEEKSS*" gene 1761707..1762573 /gene="rodZ" /locus_tag="BSU_16910" /old_locus_tag="BSU16910" promotor_no_box 1761770..1761870 /Source="Nicolas_upshift_promotors" /id="U1354" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.52947052947053" /psig="0.015984015984016" /xcortree=1494 /SigmaFactorBS="gaaggaaactatgacattattccggggaagttttatgttcgg gcattcatcaagcaatatgcagaagccgttgggcttgatgcggatcagctgtttgagg a" /listShort="pgsA, cinA, S604" /listLong="recA, S605, pbpX, S606, S607, ymdA, ymdB, S608, spoVS" /label="promotor_no_box" upshifts 1761830 /Source="Nicolas_upshifts" /id="U1354" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.52947052947053" /psig="0.015984015984016" /xcortree=1494 /SigmaFactorBS="gaaggaaactatgacattattccggggaagttttatgttcgg gcattcatcaagcaatatgcagaagccgttgggcttgatgcggatcagctgtttgagg a" /listShort="pgsA, cinA, S604" /listLong="recA, S605, pbpX, S606, S607, ymdA, ymdB, S608, spoVS" downshifts 1762533 /Source="Nicolas_upshifts" /id="D912" /incds=0 /nref=1 /ntot=107 /MaxReadThrough="5.43253" /MaxDrop="2.8328" /score="21.9507801" /energy="-8.7" /TU="U1353,U1354" /idTUdmin="U1351" /TUdmin=0 /isTUend="TRUE" CDS 1762623..1763204 /gene="pgsA" /locus_tag="BSU_16920" /old_locus_tag="BSU16920" /EC_number="2.7.8.5" /function="16.2: Construct biomass (Anabolism)" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:12682299, 15743965, 15849754, 16514141, 16850406, 27818647" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12682299, 15743965, 15849754, 16514141, 16850406, 27818647; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase" /protein_id="NP_389574.2" /db_xref="EnsemblGenomes-Gn:BSU16920" /db_xref="EnsemblGenomes-Tr:CAB13565" /db_xref="GOA:P46322" /db_xref="InterPro:IPR000462" /db_xref="InterPro:IPR004570" /db_xref="SubtiList:BG11373" /db_xref="UniProtKB/Swiss-Prot:P46322" /translation="MFNLPNKITLARIALIPIFMIIMLAPFDWGRLEVGDESIPVAHL AGAILFIIASTTDWVDGYYARKLNLVTNFGKFLDPLADKLLVSAALIILVQFDLAPAW MVIVIISREFAVTGLRLVLAGTGEVVAANMLGKIKTWAQIIAVSALLLHNLPFELVSF PFADLALWVAVFFTVVSGWEYFSKNWEALKTSN*" gene 1762623..1763204 /gene="pgsA" /locus_tag="BSU_16920" /old_locus_tag="BSU16920" CDS 1763222..1764472 /gene="cinA" /locus_tag="BSU_16930" /old_locus_tag="BSU16930" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 10438773, 11703670, 20480359; Product type r: regulator" /codon_start=1 /transl_table=11 /product="competence-damage inducible regulator" /protein_id="NP_389575.2" /db_xref="EnsemblGenomes-Gn:BSU16930" /db_xref="EnsemblGenomes-Tr:CAB13566" /db_xref="InterPro:IPR001453" /db_xref="InterPro:IPR008135" /db_xref="InterPro:IPR008136" /db_xref="InterPro:IPR036425" /db_xref="InterPro:IPR036653" /db_xref="SubtiList:BG11374" /db_xref="UniProtKB/Swiss-Prot:P46323" /translation="MEFPKKAEIIAVGSELLLGQIANTNAQFISKQLAEIGVNVFYHT AVGDNPERLKQVIRIAEERSDFIIFSGGLGPTKDDLTKETIANTLGRPLVLNDEAFQS IEDYFKRTKRTMSPNNRKQALVIEGSDVLANHFGMAPGMLTEHESRYYMLLPGPPSEL RPMFENEAKPLLLKKMGSNEKIVSTVLRFFGIGESQLEADLEDIIDAQTNPTIAPLAA DGEVTLRLTAKHADEKETERLLKETEAVILERVGEFFYGYDDTSLVKELSIACKEKGI TISAAESFTGGLFSEWLTDHSGASKLFAGGVVCYTNDVKQNVLGVKKETLDRFGAVSK ECASELAKGVQKLTGSDIGISFTGVAGPDAQEGHEPGHVFIGISANGKEEVHEFHFAG SRTGIRKRGAKYGCHLILKLLEQK*" gene 1763222..1764472 /gene="cinA" /locus_tag="BSU_16930" /old_locus_tag="BSU16930" S_feature 1764473..1764599 /Source="Nicolas_S_feature" /locus_tag="new_1764473_1764599" /HighExp="LBGstat, LBGtran, G135, Lbstat, G150, C30, LBGexp, dia0, S0, G180" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="Sig-, SigA" /TUshortPSig="0.016, 0.998" /TUlongSig="SigA" /TUlongPSig="0.987" /label="S604" promotor_-35 1764579..1764586 /Source="Nicolas_upshift_promotors" /id="U1355" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.863136863136863" /psig=1 /xcortree=1499 /SigmaFactorBS="tcacgccaagaaaaaatccgaatatgcgttcgctttttTCTT GGCAaatcccttcaaacaGGGTATAGTATATGTAGTGGtaacataaaggaggaaaaaa t" /listShort="recA, S605, pbpX" /listLong="S606, S607, ymdA, ymdB, S608, spoVS" /label="promotor_-35" promotor_-10 1764601..1764620 /Source="Nicolas_upshift_promotors" /id="U1355" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.863136863136863" /psig=1 /xcortree=1499 /SigmaFactorBS="tcacgccaagaaaaaatccgaatatgcgttcgctttttTCTT GGCAaatcccttcaaacaGGGTATAGTATATGTAGTGGtaacataaaggaggaaaaaa t" /listShort="recA, S605, pbpX" /listLong="S606, S607, ymdA, ymdB, S608, spoVS" /label="promotor_-10" upshifts 1764601 /Source="Nicolas_upshifts" /id="U1355" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.863136863136863" /psig=1 /xcortree=1499 /SigmaFactorBS="tcacgccaagaaaaaatccgaatatgcgttcgctttttTCTT GGCAaatcccttcaaacaGGGTATAGTATATGTAGTGGtaacataaaggaggaaaaaa t" /listShort="recA, S605, pbpX" /listLong="S606, S607, ymdA, ymdB, S608, spoVS" CDS 1764645..1765691 /gene="recA" /locus_tag="BSU_16940" /old_locus_tag="BSU16940" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:11555642, 16024744, 16061691, 16267290, 17229847, 22720735, 25939832, 26001966, 26930481, 28344191" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11555642, 16024744, 16061691, 16267290, 17229847, 22720735, 25939832, 26001966, 26930481, 28344191; Product type f: factor" /codon_start=1 /transl_table=11 /product="multifunctional SOS repair factor" /protein_id="NP_389576.2" /db_xref="EnsemblGenomes-Gn:BSU16940" /db_xref="EnsemblGenomes-Tr:CAB13567" /db_xref="GOA:P16971" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR013765" /db_xref="InterPro:IPR020584" /db_xref="InterPro:IPR020587" /db_xref="InterPro:IPR020588" /db_xref="InterPro:IPR023400" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG10721" /db_xref="UniProtKB/Swiss-Prot:P16971" /translation="MSDRQAALDMALKQIEKQFGKGSIMKLGEKTDTRISTVPSGSLA LDTALGIGGYPRGRIIEVYGPESSGKTTVALHAIAEVQQQGGQAAFIDAEHALDPVYA QKLGVNIEELLLSQPDTGEQALEIAEALVRSGAVDIVVVDSVAALVPKAEIEGDMGDS HVGLQARLMSQALRKLSGAINKSKTIAIFINQIREKVGVMFGNPETTPGGRALKFYSS VRLEVRRAEQLKQGNDVMGNKTKIKVVKNKVAPPFRTAEVDIMYGEGISKEGEIIDLG TELDIVQKSGSWYSYEEERLGQGRENAKQFLKENKDIMLMIQEQIREHYGLDNNGVVQ QQAEETQEELEFEE*" gene 1764645..1765691 /gene="recA" /locus_tag="BSU_16940" /old_locus_tag="BSU16940" downshifts 1765703 /Source="Nicolas_upshifts" /id="D913" /incds=0 /nref=201 /ntot=262 /MaxReadThrough="4.54659" /MaxDrop="9.405" /score="23.91264" /energy="-9.7" /TU="U1355" /idTUdmin="U1353" /TUdmin="-1" /isTUend="TRUE" S_feature 1765748..1765813 /Source="Nicolas_S_feature" /locus_tag="new_1765748_1765813" /HighExp="S7, S5, S8, S4, H2O2, C30, T5.0H, S6, ferm, Cold" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="Sig-, SigA, SigA" /TUlongPSig="0.016, 0.998, 0.987" /label="S605" promotor_-35 1765785..1765794 /Source="Nicolas_upshift_promotors" /id="U1356" /multdbtbs="SigW,SigX" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=2507 /SigmaFactorBS="caaaaaaatgataaaaatattgctttttttGACAACTTTTtt agggctttatTCGTCTAACAAAACGTgtgcaaaatggaatttattttgggaggaaaaa a" /listShort="pbpX, S606" /listLong="S607, ymdA, ymdB, S608, spoVS, S609, tdh, kbl, ymcB, ymcA" /label="promotor_-35" promotor_-10 1765807..1765822 /Source="Nicolas_upshift_promotors" /id="U1356" /multdbtbs="SigW,SigX" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=2507 /SigmaFactorBS="caaaaaaatgataaaaatattgctttttttGACAACTTTTtt agggctttatTCGTCTAACAAAACGTgtgcaaaatggaatttattttgggaggaaaaa a" /listShort="pbpX, S606" /listLong="S607, ymdA, ymdB, S608, spoVS, S609, tdh, kbl, ymcB, ymcA" /label="promotor_-10" upshifts 1765815 /Source="Nicolas_upshifts" /id="U1356" /multdbtbs="SigW,SigX" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=2507 /SigmaFactorBS="caaaaaaatgataaaaatattgctttttttGACAACTTTTtt agggctttatTCGTCTAACAAAACGTgtgcaaaatggaatttattttgggaggaaaaa a" /listShort="pbpX, S606" /listLong="S607, ymdA, ymdB, S608, spoVS, S609, tdh, kbl, ymcB, ymcA" CDS 1765859..1767034 /gene="pbpX" /locus_tag="BSU_16950" /old_locus_tag="BSU16950" /function="16.13: Shape" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:14762009, 15758244, 21856855" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 14762009, 15758244, 21856855; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="penicillin-binding endopeptidase X (lysozyme resistance)" /protein_id="NP_389577.1" /db_xref="EnsemblGenomes-Gn:BSU16950" /db_xref="EnsemblGenomes-Tr:CAB13568" /db_xref="GOA:O31773" /db_xref="InterPro:IPR001466" /db_xref="InterPro:IPR012338" /db_xref="SubtiList:BG12642" /db_xref="UniProtKB/Swiss-Prot:O31773" /translation="MTSPTRRRTAKRRRRKLNKRGKLLFGLLAVMVCITIWNALHRNS EENEPSQETAAVSNTDQKKEVKKKTAKKSEEQIKTVDRNQKISNYLKEIGFSGTAMIV RNGEIVTNKGFGYADRKHYIQNNPLTSFYVGSSQKALIATAILQLEEKGKLQTSDPVS TYLPHFPNGQTITLKNLLTHTSGINGHIEGNGAITPDDLIKDIELQGIKRQPGVWDYK DSNYSVLAYIIAEVSGEPYEQYIKNHIFKPAGMTHAGFYKTYEKEPYPAVGYKMEGSK TVTPYIPDLSQLYGAGDIYMSAIDMYKFDQALIDGKLYSQKSYEKMFTPGSSSTYGMG FYVAPGSYSNHGVMPGFNILNSFSKSGQTIVILFSNIQNNAKLGQVNNKIYQLLNQE* " gene 1765859..1767034 /gene="pbpX" /locus_tag="BSU_16950" /old_locus_tag="BSU16950" S_feature 1767035..1767134 /Source="Nicolas_S_feature" /locus_tag="new_1767035_1767134" /HighExp="dia0, LBGexp, Lbexp, Oxctl, Paraq, H2O2, C30, G150, Mt0, HPh" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.54369999999999996" /TUshortSig="SigWXY" /TUshortPSig=1 /TUlongSig="SigA, Sig-, SigA, SigA" /TUlongPSig="1, 0.016, 0.998, 0.987" /label="S606" promotor_-35 1767108..1767115 /Source="Nicolas_upshift_promotors" /id="U1357" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.791208791208791" /psig=1 /xcortree=1906 /SigmaFactorBS="aagaagactggcctgcaaacgttaagatggcaAGCTTGACaa gtatttccgacACATTTACAATGAAGTTGTAacatttgtttttttaacatgattgtta a" /listShort="S607, ymdA, ymdB, S608, spoVS" /listLong="S609, tdh, kbl, ymcB, ymcA" /label="promotor_-35" promotor_-10 1767129..1767148 /Source="Nicolas_upshift_promotors" /id="U1357" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.791208791208791" /psig=1 /xcortree=1906 /SigmaFactorBS="aagaagactggcctgcaaacgttaagatggcaAGCTTGACaa gtatttccgacACATTTACAATGAAGTTGTAacatttgtttttttaacatgattgtta a" /listShort="S607, ymdA, ymdB, S608, spoVS" /listLong="S609, tdh, kbl, ymcB, ymcA" /label="promotor_-10" S_feature 1767136..1767309 /Source="Nicolas_S_feature" /locus_tag="new_1767136_1767309" /HighExp="M9-stat, T3.30H, BC, T2.0H, T3.0H, T-1.40H, T1.30H, T2.30H, T4.0H, C90" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="SigWXY, SigA, Sig-, SigA, SigA" /TUlongPSig="1, 1, 0.016, 0.998, 0.987" /label="S607" upshifts 1767136 /Source="Nicolas_upshifts" /id="U1357" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.791208791208791" /psig=1 /xcortree=1906 /SigmaFactorBS="aagaagactggcctgcaaacgttaagatggcaAGCTTGACaa gtatttccgacACATTTACAATGAAGTTGTAacatttgtttttttaacatgattgtta a" /listShort="S607, ymdA, ymdB, S608, spoVS" /listLong="S609, tdh, kbl, ymcB, ymcA" CDS 1767310..1768872 /gene="rny" /locus_tag="BSU_16960" /old_locus_tag="BSU16960" /EC_number="3.1.26.-" /function="16.6: Maintain" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:12682299, 17005971, 19779461, 21803996, 21815947, 21862575, 22720735, 25402410, 26797123" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12682299, 17005971, 19779461, 21803996, 21815947, 21862575, 22720735, 25402410, 26797123; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="endoribonuclease Y" /protein_id="NP_389578.1" /db_xref="EnsemblGenomes-Gn:BSU16960" /db_xref="EnsemblGenomes-Tr:CAB13569" /db_xref="GOA:O31774" /db_xref="InterPro:IPR003607" /db_xref="InterPro:IPR004087" /db_xref="InterPro:IPR004088" /db_xref="InterPro:IPR006674" /db_xref="InterPro:IPR006675" /db_xref="InterPro:IPR015946" /db_xref="InterPro:IPR017705" /db_xref="InterPro:IPR022711" /db_xref="InterPro:IPR036612" /db_xref="SubtiList:BG13420" /db_xref="UniProtKB/Swiss-Prot:O31774" /translation="MTPIMMVLISILLILLGLVVGYFVRKTIAEAKIAGARGAAEQIL EDAKRDAEALKKEALLEAKDEIHKLRIDAEQEVRERRNELQKQENRLLQKEENLDRKH EGIDKREAMLEKKDHSLNERQQHIEEMESKVDEMIRMQQSELERISSLTRDEAKQIIL ERVENELSHDIAIMTKETENRAKEEADKKAKNILSLALQRCAADHVAETTVSVVNLPN DEMKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVILSGFDPIRRETARIALDKLVQD GRIHPARIEEMVEKSRREVDDYIREMGEQTTFEVGVHGLHPDLIKILGRLKFRTSYGQ NVLKHSMEVAFLAGLMASELGEDAKLAKRAGLLHDIGKAIDHEVEGSHVEIGVELATK YKEHPVVINSIASHHGDEEPTSIIAVLVAAADALSAARPGARSETLENYIRRLEKLEE ISESYEGVEKSFAIQAGREVRIMVKPDSINDLEAHRLARDIRKRIEDELDYPGHIKVT VIRETRAVEYAK*" gene 1767310..1768872 /gene="rny" /locus_tag="BSU_16960" /old_locus_tag="BSU16960" downshifts 1768849 /Source="Nicolas_upshifts" /id="D914" /incds=0 /nref=243 /ntot=268 /MaxReadThrough="5.32126" /MaxDrop="5.3789" /score="10.4712371" /energy="-9" /TU="U1357" /idTUdmin="U1357" /TUdmin="-1342" /isTUend="FALSE" CDS 1768941..1769735 /gene="pdeB" /locus_tag="BSU_16970" /old_locus_tag="BSU16970" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:19376879, 21856853, 24163345, 26904951, 26906740" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 19376879, 21856853, 24163345, 26904951, 26906740; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="2'3' and 3'5' cyclic nucleotide monophosphates phosphodiesterase involved in biofilm formation" /protein_id="NP_389579.2" /db_xref="EnsemblGenomes-Gn:BSU16970" /db_xref="EnsemblGenomes-Tr:CAB13570" /db_xref="GOA:O31775" /db_xref="InterPro:IPR005235" /db_xref="InterPro:IPR029052" /db_xref="PDB:4B2O" /db_xref="SubtiList:BG13421" /db_xref="UniProtKB/Swiss-Prot:O31775" /translation="MRILFIGDVVGSPGRDMVKEYVPKLKTKYKPHFTIINGENAAHG KGLTEKIYHSLIQSGADAITMGNHTWDKKEIFDFIDDVPNLVRPANFPEGTPGKGITY VKANGKELAVINLQGRTFLPPLDDPFLKADELIAEAAKRTPYIFIDFHAEATSEKLAL GWYTDGRASAVVGTHTHVQTADNRILPKGTAYITDVGMTGPYDGILGMDRETIIKRFK TNLPVRFTVAEGKTTLSGVVIDIDDQTKKAVKIERILINDDHMFFE*" gene 1768941..1769735 /gene="pdeB" /locus_tag="BSU_16970" /old_locus_tag="BSU16970" promotor_-35 1769490..1769495 /Source="Nicolas_upshift_promotors" /id="U1358" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.91008991008991" /psig="0.91008991008991" /xcortree=1456 /SigmaFactorBS="cgtgcaaacagcggataacCGCATTttgccgaagggaacgGC ATATATTACTGATGTGGgaatgactggcccgtatgacggtatactggggatggacaga g" /listShort="S608, spoVS, S609" /listLong="tdh, kbl, ymcB, ymcA" /label="promotor_-35" promotor_-10 1769511..1769529 /Source="Nicolas_upshift_promotors" /id="U1358" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.91008991008991" /psig="0.91008991008991" /xcortree=1456 /SigmaFactorBS="cgtgcaaacagcggataacCGCATTttgccgaagggaacgGC ATATATTACTGATGTGGgaatgactggcccgtatgacggtatactggggatggacaga g" /listShort="S608, spoVS, S609" /listLong="tdh, kbl, ymcB, ymcA" /label="promotor_-10" upshifts 1769531 /Source="Nicolas_upshifts" /id="U1358" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.91008991008991" /psig="0.91008991008991" /xcortree=1456 /SigmaFactorBS="cgtgcaaacagcggataacCGCATTttgccgaagggaacgGC ATATATTACTGATGTGGgaatgactggcccgtatgacggtatactggggatggacaga g" /listShort="S608, spoVS, S609" /listLong="tdh, kbl, ymcB, ymcA" promotor_-35 1769779..1769784 /Source="Nicolas_upshift_promotors" /id="U1359" /multdbtbs="SigH" /comp="M3" /sig="SigEF" /pcomp="0.916083916083916" /psig="0.916083916083916" /xcortree=759 /SigmaFactorBS="gttgaacatatggttattttataaaaatattaaaaagaaaag caGGAATAtagcaactccttagtGAATATAGTAAAAATGGAAggtagcccgctatttt t" /listShort="S608, spoVS, S609, tdh" /listLong="kbl, ymcB, ymcA" /label="promotor_-35" S_feature 1769795..1769934 /Source="Nicolas_S_feature" /locus_tag="new_1769795_1769934" /HighExp="T5.0H, LoTm, BT, B60, S8, M9-stat, S6, BC, B36, S4" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigEF, SigEF, SigA" /TUshortPSig="0.916, 0.91, 1" /TUlongSig="SigWXY, SigA, Sig-, SigA, SigA" /TUlongPSig="1, 1, 0.016, 0.998, 0.987" /label="S608" upshifts 1769795 /Source="Nicolas_upshifts" /id="U1359" /multdbtbs="SigH" /comp="M3" /sig="SigEF" /pcomp="0.916083916083916" /psig="0.916083916083916" /xcortree=759 /SigmaFactorBS="gttgaacatatggttattttataaaaatattaaaaagaaaag caGGAATAtagcaactccttagtGAATATAGTAAAAATGGAAggtagcccgctatttt t" /listShort="S608, spoVS, S609, tdh" /listLong="kbl, ymcB, ymcA" promotor_-10 1769800..1769818 /Source="Nicolas_upshift_promotors" /id="U1359" /multdbtbs="SigH" /comp="M3" /sig="SigEF" /pcomp="0.916083916083916" /psig="0.916083916083916" /xcortree=759 /SigmaFactorBS="gttgaacatatggttattttataaaaatattaaaaagaaaag caGGAATAtagcaactccttagtGAATATAGTAAAAATGGAAggtagcccgctatttt t" /listShort="S608, spoVS, S609, tdh" /listLong="kbl, ymcB, ymcA" /label="promotor_-10" upshifts complement(1769827) /Source="Nicolas_upshifts" /id="U1360" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.763236763236763" /psig="0.0679320679320679" /xcortree=695 /SigmaFactorBS="acaatcattattagatgttgctaTCCAAaaagccatCCCCAC AATGCTTTtcaaaaatagcgggctaccttccatttttactatattcactaaggagttg c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 complement(1769838..1769851) /Source="Nicolas_upshift_promotors" /id="U1360" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.763236763236763" /psig="0.0679320679320679" /xcortree=695 /SigmaFactorBS="acaatcattattagatgttgctaTCCAAaaagccatCCCCAC AATGCTTTtcaaaaatagcgggctaccttccatttttactatattcactaaggagttg c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 complement(1769860..1769864) /Source="Nicolas_upshift_promotors" /id="U1360" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.763236763236763" /psig="0.0679320679320679" /xcortree=695 /SigmaFactorBS="acaatcattattagatgttgctaTCCAAaaagccatCCCCAC AATGCTTTtcaaaaatagcgggctaccttccatttttactatattcactaaggagttg c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" downshifts complement(1769871) /Source="Nicolas_upshifts" /id="D915" /incds=0 /nref=5 /ntot=35 /MaxReadThrough="1.51152" /MaxDrop="3.63977" /score="3.80280375" /energy="-6.7" /TU="NA" /idTUdmin="U1366" /TUdmin=10274 /isTUend="FALSE" CDS 1769935..1770195 /gene="spoVS" /locus_tag="BSU_16980" /old_locus_tag="BSU16980" /function="16.3: Control" /function="16.5: Explore" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:7559352, 16428420, 18562273" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7559352, 16428420, 18562273; Product type r: regulator" /codon_start=1 /transl_table=11 /product="regulator required for dehydratation of the spore core and assembly of the coat (stage V sporulation)" /protein_id="NP_389580.1" /db_xref="EnsemblGenomes-Gn:BSU16980" /db_xref="EnsemblGenomes-Tr:CAB13571" /db_xref="GOA:P45693" /db_xref="InterPro:IPR007347" /db_xref="SubtiList:BG11245" /db_xref="UniProtKB/Swiss-Prot:P45693" /translation="MEILKVSAKSSPNSVAGALAGVLRERGAAEIQAIGAGALNQAVK AVAIARGFVAPSGVDLICIPAFTDIQIDGEERTAIKLIVEPR*" gene 1769935..1770195 /gene="spoVS" /locus_tag="BSU_16980" /old_locus_tag="BSU16980" downshifts 1770147 /Source="Nicolas_upshifts" /id="D916" /incds=0 /nref=1 /ntot=27 /MaxReadThrough="8.31914" /MaxDrop="4.27515" /score="5.18548432" /energy="-12.5" /TU="U1357,U1358,U1359" /idTUdmin="U1357" /TUdmin="-44" /isTUend="FALSE" downshifts complement(1770179) /Source="Nicolas_upshifts" /id="D917" /incds=0 /nref=3 /ntot=15 /MaxReadThrough="1.16149" /MaxDrop="3.88837" /score="3.80280375" /energy="-6.7" /TU="NA" /idTUdmin="U1366" /TUdmin=9966 /isTUend="FALSE" downshifts 1770191 /Source="Nicolas_upshifts" /id="D918" /incds=0 /nref=171 /ntot=265 /MaxReadThrough="4.08266" /MaxDrop="5.124" /score="5.18548432" /energy="-12.5" /TU="U1358,U1359" /idTUdmin="U1357" /TUdmin=0 /isTUend="TRUE" S_feature 1770236..1770410 /Source="Nicolas_S_feature" /locus_tag="new_1770236_1770410" /HighExp="S6, S8, S7, M9-stat, Lbstat, BT, S5, T1.30H, T2.0H, M0t90" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigEF, SigEF" /TUshortPSig="0.916, 0.91" /TUlongSig="SigA, SigWXY" /TUlongPSig="1, 1" /label="S609" promotor_-35 1770394..1770401 /Source="Nicolas_upshift_promotors" /id="U1361" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.825174825174825" /psig="0.999000999001" /xcortree=322 /SigmaFactorBS="ttttcaagacagatacttttgtccttctggaaaagacagttc TGTTTACGcttattccatatcaTGGTACAATCCGAATATAACaagaatttttcaagga g" /listShort="tdh, kbl, ymcB, ymcA" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 1770412 /Source="Nicolas_upshifts" /id="U1361" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.825174825174825" /psig="0.999000999001" /xcortree=322 /SigmaFactorBS="ttttcaagacagatacttttgtccttctggaaaagacagttc TGTTTACGcttattccatatcaTGGTACAATCCGAATATAACaagaatttttcaagga g" /listShort="tdh, kbl, ymcB, ymcA" /GFF_Attribute="listLong" promotor_-10 1770416..1770435 /Source="Nicolas_upshift_promotors" /id="U1361" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.825174825174825" /psig="0.999000999001" /xcortree=322 /SigmaFactorBS="ttttcaagacagatacttttgtccttctggaaaagacagttc TGTTTACGcttattccatatcaTGGTACAATCCGAATATAACaagaatttttcaagga g" /listShort="tdh, kbl, ymcB, ymcA" /GFF_Attribute="listLong" /label="promotor_-10" CDS 1770461..1771504 /gene="tdh" /locus_tag="BSU_16990" /old_locus_tag="BSU16990" /EC_number="1.1.1.103" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 8519804, 16817900, 22720735; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="threonine 3-dehydrogenase" /protein_id="NP_389581.1" /db_xref="EnsemblGenomes-Gn:BSU16990" /db_xref="EnsemblGenomes-Tr:CAB13572" /db_xref="GOA:O31776" /db_xref="InterPro:IPR002328" /db_xref="InterPro:IPR004627" /db_xref="InterPro:IPR011032" /db_xref="InterPro:IPR013149" /db_xref="InterPro:IPR013154" /db_xref="InterPro:IPR020843" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG12685" /db_xref="UniProtKB/Swiss-Prot:O31776" /translation="MQSGKMKALMKKDGAFGAVLTEVPIPEIDKHEVLIKVKAASICG TDVHIYNWDQWARQRIKTPYVFGHEFSGIVEGVGENVSSVKVGEYVSAETHIVCGECV PCLTGKSHVCTNTAIIGVDTAGCFAEYVKVPADNIWRNPADMDPSIASIQEPLGNAVH TVLESQPAGGTTAVIGCGPIGLMAVAVAKAAGASQVIAIDKNEYRLRLAKQMGATCTV SIEKEDPLKIVSALTSGEGADLVCEMSGHPSAIAQGLAMAANGGRFHILSLPEHPVTI DLTNKVVFKGLTIQGITGRKMFSTWRQVSQLISSNMIDLAPVITHQFPLEEFEKGFEL MRSGQCGKVILIP*" gene 1770461..1771504 /gene="tdh" /locus_tag="BSU_16990" /old_locus_tag="BSU16990" CDS 1771517..1772695 /gene="kbl" /locus_tag="BSU_17000" /old_locus_tag="BSU17000" /EC_number="2.3.1.29" /function="16.8: Protect" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 17146529, 22720735; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="2-amino-3-ketobutyrate CoA ligase (glycine acetyl transferase)" /protein_id="NP_389582.1" /db_xref="EnsemblGenomes-Gn:BSU17000" /db_xref="EnsemblGenomes-Tr:CAB13573" /db_xref="GOA:O31777" /db_xref="InterPro:IPR001917" /db_xref="InterPro:IPR004723" /db_xref="InterPro:IPR004839" /db_xref="InterPro:IPR010962" /db_xref="InterPro:IPR015421" /db_xref="InterPro:IPR015422" /db_xref="InterPro:IPR015424" /db_xref="SubtiList:BG12610" /db_xref="UniProtKB/Swiss-Prot:O31777" /translation="MTKEFEFLKAELNSMKENHTWQDIKQLESMQGPSVTVNHQKVIQ LSSNNYLGFTSHPRLINAAQEAVQQYGAGTGSVRTIAGTFTMHQELEKKLAAFKKTEA ALVFQSGFTTNQGVLSSILSKEDIVISDELNHASIIDGIRLTKADKKVYQHVNMSDLE RVLRKSMNYRMRLIVTDGVFSMDGNIAPLPDIVELAEKYDAFVMVDDAHASGVLGENG RGTVNHFGLDGRVHIQVGTLSKAIGVLGGYAAGSKVLIDYLRHKGRPFLFSTSHPPAV TAACMEAIDVLLEEPEHMERLWENTAYFKAMLVKMGLTLTKSETPILPILIGDEGVAK QFSDQLLSRGVFAQSIVFPTVAKGKARIRTIITAEHTKDELDQALDVIEKTAKELQLL *" gene 1771517..1772695 /gene="kbl" /locus_tag="BSU_17000" /old_locus_tag="BSU17000" downshifts 1772677 /Source="Nicolas_upshifts" /id="D919" /incds=0 /nref=3 /ntot=25 /MaxReadThrough="5.75732" /MaxDrop="3.4918" /score="4.73069387" /energy="-12.5" /TU="U1361" /idTUdmin="U1359" /TUdmin=1936 /isTUend="FALSE" promotor_-35 1772775..1772778 /Source="Nicolas_upshift_promotors" /id="U1362" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.681318681318681" /psig=1 /xcortree=2732 /SigmaFactorBS="ttccttattgattattattctcaatgagtgtacaatgatagg ttgccaGTTGtgcagagcttcaatAACCTTTATACTGAAGGGTGgaagtttggtttga a" /listShort="ymcB, ymcA" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 1772787 /Source="Nicolas_upshifts" /id="U1362" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.681318681318681" /psig=1 /xcortree=2732 /SigmaFactorBS="ttccttattgattattattctcaatgagtgtacaatgatagg ttgccaGTTGtgcagagcttcaatAACCTTTATACTGAAGGGTGgaagtttggtttga a" /listShort="ymcB, ymcA" /GFF_Attribute="listLong" promotor_-10 1772793..1772812 /Source="Nicolas_upshift_promotors" /id="U1362" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.681318681318681" /psig=1 /xcortree=2732 /SigmaFactorBS="ttccttattgattattattctcaatgagtgtacaatgatagg ttgccaGTTGtgcagagcttcaatAACCTTTATACTGAAGGGTGgaagtttggtttga a" /listShort="ymcB, ymcA" /GFF_Attribute="listLong" /label="promotor_-10" CDS 1772843..1774372 /gene="miaB" /locus_tag="BSU_17010" /old_locus_tag="BSU17010" /EC_number="2.8.4.3" /function="16.3: Control" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:15175311, 18307109, 20472640, 20584901, 22720735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15175311, 18307109, 20472640, 20584901, 22720735; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="enzyme for ms(2)i(6)A formation for tRNA modification" /protein_id="NP_389583.1" /db_xref="EnsemblGenomes-Gn:BSU17010" /db_xref="EnsemblGenomes-Tr:CAB13574" /db_xref="GOA:O31778" /db_xref="InterPro:IPR002792" /db_xref="InterPro:IPR005839" /db_xref="InterPro:IPR006463" /db_xref="InterPro:IPR006638" /db_xref="InterPro:IPR007197" /db_xref="InterPro:IPR013848" /db_xref="InterPro:IPR020612" /db_xref="InterPro:IPR023404" /db_xref="SubtiList:BG13418" /db_xref="UniProtKB/Swiss-Prot:O31778" /translation="MNEKQKLESGQVHPSDKKSEKDYSKYFEAVYIPPSLKDAKKRGK EAVTYHNDFKISEQFKGLGDGRKFYIRTYGCQMNEHDTEVMAGIFMALGYEATNSVDD ANVILLNTCAIRENAENKVFGELGHLKALKKNNPDLILGVCGCMSQEESVVNRILKKH PFVDMIFGTHNIHRLPELLSEAYLSKEMVVEVWSKEGDVIENLPKVRNGKIKGWVNIM YGCDKFCTYCIVPYTRGKERSRRPEDIIQEVRRLASEGYKEITLLGQNVNAYGKDFED MTYGLGDLMDELRKIDIPRIRFTTSHPRDFDDRLIEVLAKGGNLLDHIHLPVQSGSSE VLKLMARKYDRERYMELVRKIKEAMPNASLTTDIIVGFPNETDEQFEETLSLYREVEF DSAYTFIYSPREGTPAAKMKDNVPMRVKKERLQRLNALVNEISAKKMKEYEGKVVEVL VEGESKNNPDILAGYTEKSKLVNFKGPKEAIGKIVRVKIQQAKTWSLDGEMVGEAIEV K*" gene 1772843..1774372 /gene="miaB" /locus_tag="BSU_17010" /old_locus_tag="BSU17010" CDS 1774374..1774805 /gene="ricA" /locus_tag="BSU_17020" /old_locus_tag="BSU17020" /function="16.5: Explore" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:10712692, 15175311, 15661000, 22720735, 23490197, 26434553, 27501195, 28295778" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10712692, 15175311, 15661000, 22720735, 23490197, 26434553, 27501195, 28295778; Product type r: regulator" /codon_start=1 /transl_table=11 /product="master regulator for biofilm formation via regulation of RNase Y (RicAFT complex / FAD / two [4Fe-4S]2+)" /protein_id="NP_389584.1" /db_xref="EnsemblGenomes-Gn:BSU17020" /db_xref="EnsemblGenomes-Tr:CAB13575" /db_xref="InterPro:IPR010368" /db_xref="InterPro:IPR016783" /db_xref="InterPro:IPR023378" /db_xref="PDB:2PIH" /db_xref="SubtiList:BG13417" /db_xref="UniProtKB/Swiss-Prot:O31779" /translation="MTLYSKKDIVQQARNLAKMISETEEVDFFKRAEAQINENDKVST IVNQIKALQKQAVNLKHYEKHEALKQVEAKIDALQEELEEIPVIQEFRDSQMEVNDLL QLVAHTISNQVTNEIITSTGGDLLKGETGSKVKHSNNSCSL*" gene 1774374..1774805 /gene="ricA" /locus_tag="BSU_17020" /old_locus_tag="BSU17020" downshifts 1774788 /Source="Nicolas_upshifts" /id="D920" /incds=0 /nref=255 /ntot=267 /MaxReadThrough="0.9572" /MaxDrop="7.73043" /score="21.1260722" /energy="-10.3" /TU="NA" /idTUdmin="U1361" /TUdmin="-1" /isTUend="TRUE" promotor_-35 1774936..1774941 /Source="Nicolas_upshift_promotors" /id="U1363" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1090 /SigmaFactorBS="cagccgcgtataaactttatcgcacttataaGTAAAGtttct aggcacccctGCATACAATGGAACAGAAActttgtatttttatattttatttataaaa a" /listShort="S610, cotE, mutS" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1774957..1774975 /Source="Nicolas_upshift_promotors" /id="U1363" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1090 /SigmaFactorBS="cagccgcgtataaactttatcgcacttataaGTAAAGtttct aggcacccctGCATACAATGGAACAGAAActttgtatttttatattttatttataaaa a" /listShort="S610, cotE, mutS" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 1774965..1775066 /Source="Nicolas_S_feature" /locus_tag="new_1774965_1775066" /HighExp="S3, S5, S8, S4, S6, S7, B36, BT, Pyr, B60" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigEF" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S610" upshifts 1774965 /Source="Nicolas_upshifts" /id="U1363" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1090 /SigmaFactorBS="cagccgcgtataaactttatcgcacttataaGTAAAGtttct aggcacccctGCATACAATGGAACAGAAActttgtatttttatattttatttataaaa a" /listShort="S610, cotE, mutS" /GFF_Attribute="listLong" CDS 1775067..1775612 /gene="cotE" /locus_tag="BSU_17030" /old_locus_tag="BSU17030" /function="16.13: Shape" /function="16.5: Explore" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:11737650, 14563859, 14973022, 17172339, 20023017, 22773792, 25259857, 26821119, 27320701" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11737650, 14563859, 14973022, 17172339, 20023017, 22773792, 25259857, 26821119, 27320701; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="morphogenic spore protein" /protein_id="NP_389585.1" /db_xref="EnsemblGenomes-Gn:BSU17030" /db_xref="EnsemblGenomes-Tr:CAB13576" /db_xref="GOA:P14016" /db_xref="InterPro:IPR018901" /db_xref="SubtiList:BG10494" /db_xref="UniProtKB/Swiss-Prot:P14016" /translation="MSEYREIITKAVVAKGRKFTQCTNTISPEKKPSSILGGWIINHK YDAEKIGKTVEIEGYYDINVWYSYADNTKTEVVTERVKYVDVIKLRYRDNNYLDDEHE VIAKVLQQPNCLEVTISPNGNKIVVQAEREFLAEVVGETKVVVEVNPDWEEDDEEDWE DELDEELEDINPEFLVGDPEE*" gene 1775067..1775612 /gene="cotE" /locus_tag="BSU_17030" /old_locus_tag="BSU17030" downshifts 1775606 /Source="Nicolas_upshifts" /id="D921" /incds=0 /nref=64 /ntot=97 /MaxReadThrough="4.37388" /MaxDrop="8.23792" /score="10.7927556" /energy="-12.6" /TU="U1363" /idTUdmin="U1363" /TUdmin="-745" /isTUend="FALSE" downshifts complement(1775613) /Source="Nicolas_upshifts" /id="D922" /incds=0 /nref=1 /ntot=4 /MaxReadThrough="4.21458" /MaxDrop="3.44208" /score="12.3953461" /energy="-11.4" /TU="NA" /idTUdmin="U1366" /TUdmin=4532 /isTUend="FALSE" promotor_-35 1775670..1775673 /Source="Nicolas_upshift_promotors" /id="U1364" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.798201798201798" /psig=1 /xcortree=2577 /SigmaFactorBS="agtacccccaagtctcttttttatattgatatatcattCTTT tatcactttttgttTATGTTATAATGAAGGTTGGaaaatagaaacgttgatacatagt g" /listShort="mutS, mutL" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1775688..1775707 /Source="Nicolas_upshift_promotors" /id="U1364" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.798201798201798" /psig=1 /xcortree=2577 /SigmaFactorBS="agtacccccaagtctcttttttatattgatatatcattCTTT tatcactttttgttTATGTTATAATGAAGGTTGGaaaatagaaacgttgatacatagt g" /listShort="mutS, mutL" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1775692 /Source="Nicolas_upshifts" /id="U1364" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.798201798201798" /psig=1 /xcortree=2577 /SigmaFactorBS="agtacccccaagtctcttttttatattgatatatcattCTTT tatcactttttgttTATGTTATAATGAAGGTTGGaaaatagaaacgttgatacatagt g" /listShort="mutS, mutL" /GFF_Attribute="listLong" CDS 1775745..1778321 /gene="mutS" /locus_tag="BSU_17040" /old_locus_tag="BSU17040" /function="16.5: Explore" /function="16.6: Maintain" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:15375129, 16269814, 23998896, 26343983" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15375129, 16269814, 23998896, 26343983; Product type f: factor" /codon_start=1 /transl_table=11 /product="DNA mismatch repair recognition factor" /protein_id="NP_389586.2" /db_xref="EnsemblGenomes-Gn:BSU17040" /db_xref="EnsemblGenomes-Tr:CAB13577" /db_xref="GOA:P49849" /db_xref="InterPro:IPR000432" /db_xref="InterPro:IPR005748" /db_xref="InterPro:IPR007695" /db_xref="InterPro:IPR007696" /db_xref="InterPro:IPR007860" /db_xref="InterPro:IPR007861" /db_xref="InterPro:IPR016151" /db_xref="InterPro:IPR017261" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR036187" /db_xref="InterPro:IPR036678" /db_xref="SubtiList:BG11403" /db_xref="UniProtKB/Swiss-Prot:P49849" /translation="MAGYTPMIQQYLKIKAEHQDAFLFFRLGDFYEMFFEDAKKASQE LEITLTSRDGGAAEKIPMCGVPYHSASAYIEQLIKKGYKVAICEQTEDPKAAKGVVKR EVVQLITPGTVMDGKGIHESENNFIASVSACSNGYGLALSDLTTGENLAVLIERLEDV ISEIYSVGAREIVVSGSLDADTVAQLRERCGATISIEDGETDEHVTIIEHLNNEDITK TFLRLYTYLKRTQKRSLDHLQPVQVYELEEAMKIDLYSKRNLELTETIRSKNKKGSLL WLLDETKTAMGGRLLKQWIDRPLIRVNQIEERQEMVETLMSHFFEREDLRERLKEVYD LERLAGRVAFGNVNARDLIQLKESLKQVPGIKQLVASLAHDKAKERAKRIDPCGDVLE LLEEALYENPPLSVKEGNLIKDGYNQKLDEYRDASRNGKDWIARLEQQEREYTGIRSL KVGFNKVFGYYIEVTKANLHLLEEGRYERKQTLTNAERYITPELKEKEALILEAENNI CELEYELFTELREKVKQYIPRLQQLAKQMSELDALQCFATISENRHYTKPEFSKDEVE VIEGRHPVVEKVMDSQEYVPNNCMMGDNRQMLLITGPNMSGKSTYMRQIALISIMAQI GCFVPAKKAVLPIFDQIFTRIGAADDLISGQSTFMVEMLEAKNAIVNATKNSLILFDE IGRGTSTYDGMALAQAIIEYVHDHIGAKTLFSTHYHELTVLEDKLPQLKNVHVRAEEY NGTVVFLHQIKEGAADKSYGIHVAQLAELPGDLIARAQDILKELEHSGNKPEVPVQKP QVKEEPAQLSFFDEAEKPAETPKLSKKEKQVIDAFKSLNILDMTPLEAMNEMYKLQKK LH*" gene 1775745..1778321 /gene="mutS" /locus_tag="BSU_17040" /old_locus_tag="BSU17040" CDS 1778337..1780220 /gene="mutL" /locus_tag="BSU_17050" /old_locus_tag="BSU17050" /function="16.8: Protect" /function="16.5: Explore" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:15375129, 22843852, 26343983, 26384423, 27369079" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15375129, 22843852, 26343983, 26384423, 27369079; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="DNA mismatch repair endonuclease" /protein_id="NP_389587.1" /db_xref="EnsemblGenomes-Gn:BSU17050" /db_xref="EnsemblGenomes-Tr:CAB13578" /db_xref="GOA:P49850" /db_xref="InterPro:IPR002099" /db_xref="InterPro:IPR003594" /db_xref="InterPro:IPR013507" /db_xref="InterPro:IPR014721" /db_xref="InterPro:IPR014762" /db_xref="InterPro:IPR014790" /db_xref="InterPro:IPR020568" /db_xref="InterPro:IPR020667" /db_xref="InterPro:IPR036890" /db_xref="InterPro:IPR037198" /db_xref="PDB:3GAB" /db_xref="PDB:3KDG" /db_xref="PDB:3KDK" /db_xref="SubtiList:BG11402" /db_xref="UniProtKB/Swiss-Prot:P49850" /translation="MAKVIQLSDELSNKIAAGEVVERPASVVKELVENAIDADSTVIE IDIEEAGLASIRVLDNGEGMENEDCKRAFRRHATSKIKDENDLFRVRTLGFRGEALPS IASVSHLEITTSTGEGAGTKLVLQGGNIISESRSSSRKGTEIVVSNLFFNTPARLKYM KTVHTELGNITDVVNRIALAHPEVSIRLRHHGKNLLQTNGNGDVRHVLAAIYGTAVAK KMLPLHVSSLDFEVKGYIALPEITRASRNYMSSVVNGRYIKNFPLVKAVHEGYHTLLP IGRHPITFIEITMDPILVDVNVHPSKLEVRLSKETELHDLIRDGIKDVFKQQQLIPSA QVPKKSAPAIKNEQQFITFDEKPPEKKVPEKSTAPSYSPMKLSSVVKEPVDAEEKLPP LQFDAPPIVDQEQTLEVSDVSAEQPETFEQECHEEQPQPASDRVPIMYPIGQMHGTYI LAQNENGLYIIDQHAAQERIKYEYFREKVGEVEPEVQEMIVPLTFHYSTNEALIIEQH KQELESVGVFLESFGSNSYIVRCHPAWFPKGEEAELIEEIIQQVLDSKNIDIKKLREE AAIMMSCKGSIKANRHLRNDEIKALLDDLRSTSDPFTCPHGRPIIIHHSTYEMEKMFK RVM*" gene 1778337..1780220 /gene="mutL" /locus_tag="BSU_17050" /old_locus_tag="BSU17050" S_feature complement(1780123..1780617) /Source="Nicolas_S_feature" /locus_tag="new_1780123_1780617_c" /HighExp="M9-stat, LBGstat, LPhT, T2.0H, Lbstat, C30, T2.30H, M0t90, T1.30H, HiOs" /AntisenseName="mutL" /AntisenseCor="0.27126904061692803" /AntisenseRegPval="-5.2" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S611" downshifts 1780135 /Source="Nicolas_upshifts" /id="D923" /incds=1 /nref=216 /ntot=257 /MaxReadThrough="2.0064" /MaxDrop="5.37369" /score="33.4967163" /energy="-18.6" /TU="NA" /idTUdmin="U1364" /TUdmin=0 /isTUend="TRUE" downshifts complement(1780145) /Source="Nicolas_upshifts" /id="D924" /incds=1 /nref=3 /ntot=100 /MaxReadThrough="1.93338" /MaxDrop="2.7192" /score="27.1353816" /energy="-13.5" /TU="NA" /idTUdmin="U1366" /TUdmin=0 /isTUend="TRUE" promotor_-35 1780367..1780374 /Source="Nicolas_upshift_promotors" /id="U1365" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.861138861138861" /psig=1 /xcortree=478 /SigmaFactorBS="tcatggttcctccgtataacaaaatttcCATTTACAggcaat tgggattaATGTATATTTTGGGTGAGGGggtggaaacatatggcatgtggtccgaaga t" /listShort="S612" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1780389..1780408 /Source="Nicolas_upshift_promotors" /id="U1365" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.861138861138861" /psig=1 /xcortree=478 /SigmaFactorBS="tcatggttcctccgtataacaaaatttcCATTTACAggcaat tgggattaATGTATATTTTGGGTGAGGGggtggaaacatatggcatgtggtccgaaga t" /listShort="S612" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 1780399..1780532 /Source="Nicolas_S_feature" /locus_tag="new_1780399_1780532" /HighExp="LoTm, T0.30H, T1.30H, M9-stat, T3.0H, BC, T1.0H, B60, B36, T2.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.99494800000000005" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S612" upshifts 1780399 /Source="Nicolas_upshifts" /id="U1365" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.861138861138861" /psig=1 /xcortree=478 /SigmaFactorBS="tcatggttcctccgtataacaaaatttcCATTTACAggcaat tgggattaATGTATATTTTGGGTGAGGGggtggaaacatatggcatgtggtccgaaga t" /listShort="S612" /GFF_Attribute="listLong" misc_RNA complement(1780404..1780554) /gene="surX" /locus_tag="BSU_misc_RNA_89" /product="small untranslated RNA of unknown function" /note="Evidence 5: Unknown function; PubMedId : 20525796, 23155385" gene complement(1780404..1780554) /gene="surX" /locus_tag="BSU_misc_RNA_89" downshifts 1780489 /Source="Nicolas_upshifts" /id="D925" /incds=0 /nref=19 /ntot=136 /MaxReadThrough="3.45962" /MaxDrop="4.12444" /score="29.4045648" /energy="-15.3" /TU="U1365" /idTUdmin="U1364" /TUdmin=354 /isTUend="FALSE" CDS complement(1780618..1781073) /gene="ymzD" /locus_tag="BSU_17060" /old_locus_tag="BSU17060" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative integral inner membrane protein" /protein_id="YP_054578.1" /db_xref="EnsemblGenomes-Gn:BSU17060" /db_xref="EnsemblGenomes-Tr:CAE01453" /db_xref="GOA:Q7WY71" /db_xref="InterPro:IPR025912" /db_xref="SubtiList:BG14188" /db_xref="UniProtKB/Swiss-Prot:Q7WY71" /translation="MNQKEQNEHSKDFNLRSKLIGIVSITFIAAIALAVIFGGFFFGM KGLFSILGITYASNQTLALFILACFAVGLIIDPLTKIISIILAKSLSLKKTALFAFIL YFISNLITICFADYFMQSIYIPDVLLVVISAFMAIIELAFDNQPNREAA*" gene complement(1780618..1781073) /gene="ymzD" /locus_tag="BSU_17060" /old_locus_tag="BSU17060" S_feature complement(1781074..1781165) /Source="Nicolas_S_feature" /locus_tag="new_1781074_1781165_c" /HighExp="LBGstat, M9-stat, T1.0H, T1.30H, T2.0H, M0t90, MG 150, LPhT, T3.0H, M40t90" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S613" promotor_-10 complement(1781153..1781172) /Source="Nicolas_upshift_promotors" /id="U1366" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.537462537462537" /psig="0.999000999001" /xcortree=3231 /SigmaFactorBS="tgatgaaaaaggcccttccccagtggaaagggcCTTTtttgg ttttgttaaaaTATGCTATACTATTTTCGTCagaaaacagacttatagatattttggg c" /listShort="S613, ymzD, S611" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1781165) /Source="Nicolas_upshifts" /id="U1366" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.537462537462537" /psig="0.999000999001" /xcortree=3231 /SigmaFactorBS="tgatgaaaaaggcccttccccagtggaaagggcCTTTtttgg ttttgttaaaaTATGCTATACTATTTTCGTCagaaaacagacttatagatattttggg c" /listShort="S613, ymzD, S611" /GFF_Attribute="listLong" promotor_-35 complement(1781189..1781192) /Source="Nicolas_upshift_promotors" /id="U1366" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.537462537462537" /psig="0.999000999001" /xcortree=3231 /SigmaFactorBS="tgatgaaaaaggcccttccccagtggaaagggcCTTTtttgg ttttgttaaaaTATGCTATACTATTTTCGTCagaaaacagacttatagatattttggg c" /listShort="S613, ymzD, S611" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(1781228..1781785) /gene="ymcC" /locus_tag="BSU_17070" /old_locus_tag="BSU17070" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative integral inner membrane protein" /protein_id="NP_389588.1" /db_xref="EnsemblGenomes-Gn:BSU17070" /db_xref="EnsemblGenomes-Tr:CAB13579" /db_xref="GOA:O31780" /db_xref="SubtiList:BG13419" /db_xref="UniProtKB/Swiss-Prot:O31780" /translation="MNGIAWMIVFCEIAFWVVIVLGLAVRYVFKRHTLGLLFLALTPV IDLILLAATGVDLYRGASATAAHGIAAVYIGISIAYGKQMIQWADEKFQYYVTKKGTK PLKRFGMDHAKHGAKGWLRHVLAYLIGAGLLAGMIYFINDSSRTEALSGILKLWTVII GIDFLITASYFIWPKKEKASANLRS*" gene complement(1781228..1781785) /gene="ymcC" /locus_tag="BSU_17070" /old_locus_tag="BSU17070" promotor_-35 1781869..1781876 /Source="Nicolas_upshift_promotors" /id="U1367" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.404595404595405" /psig=1 /xcortree=3145 /SigmaFactorBS="ccatctttgtttttgtaacacaactgtattataaaAATTGCC CtctcatttttttCTTGTTACAATAAAGCTATGccaaaacaaattgaccatgagaaaa g" /listShort="pksA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1781889..1781908 /Source="Nicolas_upshift_promotors" /id="U1367" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.404595404595405" /psig=1 /xcortree=3145 /SigmaFactorBS="ccatctttgtttttgtaacacaactgtattataaaAATTGCC CtctcatttttttCTTGTTACAATAAAGCTATGccaaaacaaattgaccatgagaaaa g" /listShort="pksA" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-10 complement(1781891..1781909) /Source="Nicolas_upshift_promotors" /id="U1368" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.971028971028971" /psig="0.971028971028971" /xcortree=1400 /SigmaFactorBS="gcgccacgttgcttctgcaatttgttttcttcttttCTCATG gtcaatttgttttgGCATAGCTTTATTGTAACAagaaaaaaatgagagggcaattttt a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1781894 /Source="Nicolas_upshifts" /id="U1367" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.404595404595405" /psig=1 /xcortree=3145 /SigmaFactorBS="ccatctttgtttttgtaacacaactgtattataaaAATTGCC CtctcatttttttCTTGTTACAATAAAGCTATGccaaaacaaattgaccatgagaaaa g" /listShort="pksA" /GFF_Attribute="listLong" upshifts complement(1781905) /Source="Nicolas_upshifts" /id="U1368" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.971028971028971" /psig="0.971028971028971" /xcortree=1400 /SigmaFactorBS="gcgccacgttgcttctgcaatttgttttcttcttttCTCATG gtcaatttgttttgGCATAGCTTTATTGTAACAagaaaaaaatgagagggcaattttt a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" CDS 1781906..1782523 /gene="pksA" /locus_tag="BSU_17080" /old_locus_tag="BSU17080" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:17234808" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 17234808; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator of bacillaene synthesis operon" /protein_id="NP_389589.1" /db_xref="EnsemblGenomes-Gn:BSU17080" /db_xref="EnsemblGenomes-Tr:CAB13580" /db_xref="GOA:O34381" /db_xref="InterPro:IPR001647" /db_xref="InterPro:IPR009057" /db_xref="InterPro:IPR023772" /db_xref="InterPro:IPR036271" /db_xref="SubtiList:BG12647" /db_xref="UniProtKB/Swiss-Prot:O34381" /translation="MPKQIDHEKRRKQIAEATWRVILERGMEGASARNIAKEAGLSLG ALRHYFSTQDELLAFAMKLVQEKVTDRIKDIAVRDLLPKEKVLQILLEMVPTNEETIR EMEVWFAFTAYARHKKDMFDASHDGIFSGMRNLIAYLDESDLLKQNADKDIEAERLYA LVDGLALHAMLDPVRVNKDRIKRVIMQHVESICVEDTRETQKRHP*" gene 1781906..1782523 /gene="pksA" /locus_tag="BSU_17080" /old_locus_tag="BSU17080" promotor_-35 complement(1781924..1781929) /Source="Nicolas_upshift_promotors" /id="U1368" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.971028971028971" /psig="0.971028971028971" /xcortree=1400 /SigmaFactorBS="gcgccacgttgcttctgcaatttgttttcttcttttCTCATG gtcaatttgttttgGCATAGCTTTATTGTAACAagaaaaaaatgagagggcaattttt a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 1782511 /Source="Nicolas_upshifts" /id="D926" /incds=0 /nref=121 /ntot=233 /MaxReadThrough="1.91611" /MaxDrop="4.92546" /score="24.8248143" /energy="-17.1" /TU="NA" /idTUdmin="U1367" /TUdmin=0 /isTUend="TRUE" misc_feature 1782630..1782649 /Source="Nicolas_upshift_promotors" /id="U1369" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.95904095904096" /psig="0.999000999001" /xcortree=2952 /SigmaFactorBS="tttcaaagaacaaggatctctgaaaaaaatggaaaacaatca tgctgTTTGGTAAAGTGGAATGAAAgacggactgaggggtgaacactggtccatcgtt t" /listShort="S614, pksB, S615" /listLong="S616, pksC, S617, pksD, pksE, acpK, pksF, pksG, pksH, pksI, pksJ, pksL, pksM, pksN, pksR" /label="promotor_single_box" /note="Geneious type: promotor_single_box" S_feature 1782643..1782712 /Source="Nicolas_S_feature" /locus_tag="new_1782643_1782712" /HighExp="T3.0H, HiOs, T2.30H, T2.0H, BC, T3.30H, M9-tran, MG 150, M0t90, T4.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S614" upshifts 1782643 /Source="Nicolas_upshifts" /id="U1369" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.95904095904096" /psig="0.999000999001" /xcortree=2952 /SigmaFactorBS="tttcaaagaacaaggatctctgaaaaaaatggaaaacaatca tgctgTTTGGTAAAGTGGAATGAAAgacggactgaggggtgaacactggtccatcgtt t" /listShort="S614, pksB, S615" /listLong="S616, pksC, S617, pksD, pksE, acpK, pksF, pksG, pksH, pksI, pksJ, pksL, pksM, pksN, pksR" CDS 1782713..1783390 /gene="pksB" /locus_tag="BSU_17090" /old_locus_tag="BSU17090" /EC_number="3.1.2.-" /function="16.8: Protect" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 17234808, 26284661; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative hydrolase involved in bacillaene synthesis" /protein_id="NP_389590.1" /db_xref="EnsemblGenomes-Gn:BSU17090" /db_xref="EnsemblGenomes-Tr:CAB13581" /db_xref="GOA:O34769" /db_xref="InterPro:IPR001279" /db_xref="InterPro:IPR036866" /db_xref="SubtiList:BG12648" /db_xref="UniProtKB/Swiss-Prot:O34769" /translation="MNLTYKVHPIKTRYQGWTNYCYIIEDIVSRSAIVVDPSWELSKI TTTLSELEAELKAVALTHSHYDHVNLVDPLTKMFNAQVYMSKKEIDYYQFRCRNLISL DDHQTISIGNTRAQCLLTPGHTAGGMCYLFSESIFTGDTVFTEGCGICEDDGSSAEEM FDSIQRIKSEVSPHVRVYPGHSFGKSPGHSIKDLYQHNIYFQIDKKEYFVKFRTRKNQ KGIFDFK*" gene 1782713..1783390 /gene="pksB" /locus_tag="BSU_17090" /old_locus_tag="BSU17090" S_feature 1783391..1783658 /Source="Nicolas_S_feature" /locus_tag="new_1783391_1783658" /HighExp="HiOs, T2.0H, M0t90, S2, S1, T4.0H, T-5.40H, Lbstat, M9-tran, T2.30H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S615" CDS 1783500..1783766 /locus_tag="BSU_17099" /old_locus_tag="BSU17099" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_009513956.1" /translation="MKRIIMIWRPICNPGLFSYVLLYLLILYSSMEKSRKTMEQTVGK INLTDNIYRGYHQHEHATIYPVITIIKSYRSETHLLIGRVALRE*" gene 1783500..1783766 /locus_tag="BSU_17099" /old_locus_tag="BSU17099" promotor_-35 1783635..1783642 /Source="Nicolas_upshift_promotors" /id="U1370" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.914085914085914" /psig="0.993006993006993" /xcortree=556 /SigmaFactorBS="gcagaaaaacaatggagcaaactgtaggaaaaattAACTTGA CggataatatttacaGAGGTTACCATCAACATGAAcatgctactatttatccggtcat c" /listShort="S616, pksC, S617, pksD, pksE, acpK, pksF, pksG, pksH, pksI, pksJ, pksL, pksM, pksN, pksR" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1783657..1783676 /Source="Nicolas_upshift_promotors" /id="U1370" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.914085914085914" /psig="0.993006993006993" /xcortree=556 /SigmaFactorBS="gcagaaaaacaatggagcaaactgtaggaaaaattAACTTGA CggataatatttacaGAGGTTACCATCAACATGAAcatgctactatttatccggtcat c" /listShort="S616, pksC, S617, pksD, pksE, acpK, pksF, pksG, pksH, pksI, pksJ, pksL, pksM, pksN, pksR" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 1783660..1783762 /Source="Nicolas_S_feature" /locus_tag="new_1783660_1783762" /HighExp="S2, M0t90, M9-stat, HiOs, Lbstat, BC, M40t90, T2.30H, T1.30H, T2.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.62175899999999995" /TUshortSig="SigA" /TUshortPSig="0.993" /TUlongSig="SigA" /TUlongPSig="0.999" /label="S616" upshifts 1783660 /Source="Nicolas_upshifts" /id="U1370" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.914085914085914" /psig="0.993006993006993" /xcortree=556 /SigmaFactorBS="gcagaaaaacaatggagcaaactgtaggaaaaattAACTTGA CggataatatttacaGAGGTTACCATCAACATGAAcatgctactatttatccggtcat c" /listShort="S616, pksC, S617, pksD, pksE, acpK, pksF, pksG, pksH, pksI, pksJ, pksL, pksM, pksN, pksR" /GFF_Attribute="listLong" CDS 1783763..1784629 /gene="pksC" /locus_tag="BSU_17100" /old_locus_tag="BSU17100" /EC_number="2.3.1.39" /function="16.5: Explore" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:16707694, 16757561, 17234808, 26284661" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16707694, 16757561, 17234808, 26284661; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="malonyl-CoA-acyltransferase involved in bacillaene synthesis" /protein_id="NP_389591.1" /db_xref="EnsemblGenomes-Gn:BSU17100" /db_xref="EnsemblGenomes-Tr:CAB13582" /db_xref="GOA:O34825" /db_xref="InterPro:IPR004410" /db_xref="InterPro:IPR014043" /db_xref="InterPro:IPR016035" /db_xref="InterPro:IPR016036" /db_xref="InterPro:IPR020801" /db_xref="InterPro:IPR024925" /db_xref="PDB:5DZ6" /db_xref="SubtiList:BG12649" /db_xref="UniProtKB/Swiss-Prot:O34825" /translation="MITYVFPGQGSQKQGMGSGLFDEFKELTDQADEILGYSIKRLCL ENPYSNLNKTQFTQPALYVVNALSYLKKIRDEEVKPDFVAGHSLGEYNALFAAEAFDF ETGLQLVRKRGELMSLISNGGMAAVMGLNEEQVAKALKEYHLHDVDIANVNAPYQIVI SGKKDEIEKAASLFETMTEVTMVLPLNVSGAFHSRYMNKAKEEFEEFLHAFYFSPPSI PVISNVYAKPYTYEFMKQTLADQINHSVKWTDSISYLMKKGHMEFEEVGPGNVLTGLI HRIKKDAEAMPR*" gene 1783763..1784629 /gene="pksC" /locus_tag="BSU_17100" /old_locus_tag="BSU17100" S_feature 1784630..1785132 /Source="Nicolas_S_feature" /locus_tag="new_1784630_1785132" /HighExp="S2, Lbstat, M0t90, M40t90, S1, T1.0H, HiOs, T2.30H, M9-tran, T2.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.993" /TUlongSig="SigA" /TUlongPSig="0.999" /label="S617" CDS 1785133..1786107 /gene="pksD" /locus_tag="BSU_17110" /old_locus_tag="BSU17110" /EC_number="2.3.1.-" /function="16.5: Explore" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1c: Function from experimental evidences in the studied genus; PubMedId: 16707694, 17234808, 26284661; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="enzyme involved in bacillaene synthesis" /protein_id="NP_389592.2" /db_xref="EnsemblGenomes-Gn:BSU17110" /db_xref="EnsemblGenomes-Tr:CAB13583" /db_xref="GOA:O34877" /db_xref="InterPro:IPR014043" /db_xref="InterPro:IPR016035" /db_xref="InterPro:IPR016036" /db_xref="InterPro:IPR020801" /db_xref="SubtiList:BG12650" /db_xref="UniProtKB/Swiss-Prot:O34877" /translation="MNEPLVFMFSGQGSQYYHMGKELFKENTVFRQSMLEMDAIAARR IGTSIVEEIYHPGKRVSDPFDSILFSHPAIFMIEYSLYKVLEDRGIYPDYVLGSSLGE FAAAAVSGVSDAEDMLDCILEQAIIIQNSCDKGKMLAILDKPQLLNDHPQLFGNSELI SINYDSHFVISGEEDHIRKIMEDLKEKQILCQLLPVSYAFHSSLIDPAESAYAEFLRS KSFQKPSIPIVSSLTGSCLHVMDENFFWNAVRKPMMFREAIRYLESQHTCKFIDLGPS GTLAAFVKQLIPGDSADRCCSIITPFHQELKNLNTVEYFRTPERKFTR*" gene 1785133..1786107 /gene="pksD" /locus_tag="BSU_17110" /old_locus_tag="BSU17110" CDS 1786104..1788407 /gene="pksE" /locus_tag="BSU_17120" /old_locus_tag="BSU17120" /EC_number="2.3.1.-" /function="16.8: Protect" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1c: Function from experimental evidences in the studied genus; PubMedId: 16707694, 17234808, 22720735, 26284661; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="enzyme involved in bacillaene synthesis" /protein_id="NP_389593.3" /db_xref="EnsemblGenomes-Gn:BSU17120" /db_xref="EnsemblGenomes-Tr:CAB13584" /db_xref="GOA:O34787" /db_xref="InterPro:IPR004136" /db_xref="InterPro:IPR004410" /db_xref="InterPro:IPR013785" /db_xref="InterPro:IPR014043" /db_xref="InterPro:IPR014179" /db_xref="InterPro:IPR016035" /db_xref="InterPro:IPR016036" /db_xref="InterPro:IPR020801" /db_xref="PDB:5DZ7" /db_xref="SubtiList:BG12651" /db_xref="UniProtKB/Swiss-Prot:O34787" /translation="MITYVFPGQGSQQKGMGQGLFEQYQHLTDQADQILGYSIEKLCT EKSYLDVNHTEYTQPALYVVNALSYLKRVEETGRKPDFAAGHSLGEYNALMAAGAFDF ETGLRLVKKRGELMGRITGGGMAAVIGLSKEQVTAVLEEHRLYDIDVANENTPQQIVI SGPKKEIEKARAVFENTKDVKLFHPLNVSGAFHSRYMNEAKQVFKQYIDSFQFAPLAI PVISNVYAEPYHQDRLKDTLSEQMDNTVKWTDSIRFLMGRGEMEFAEIGPGTVLTGLI HRIKNEAEPLTYIPKKNPAISAHLKEQRNVQAGITAESLGSAEFKQDYHLTYAYLAGG MYRGIASKEMVVKLSRAGMMGFFGTGGLSLKEVEDAIHAIQGELGKGQAYGINLVHNM KHTESEEKMIDLLLRNQVSIVEASAFLSVTPVLVRYRAKGVKRNQNGDVICSNRLIAK ISRPEVAESFLSPAPENMLQKLLGENKITMNEAELLRCIPMADDICVEADSGGHTDGG VAYSLMPAMTSLRDEMMKKYQYRKKIRVGAAGGIGTPEAAMAAFMLGADFILTGSINQ CTVEAATSDKVKDLLQQMNVQDTAYAPAGDMFESGSKVQVLKKGVFFPARANKLYELY QRYGSIRELDAKMLAQLEEKYFKRSIEDIYKDIALHYPAADIEKAEQNPKHKMALIFR WYFRYSSKLAISGSEHSKVDYQIHCGPALGAFNQWVKGSQLENWRNRHVDEIGKKLMT ETAVLLHERMQSMYQPSHETDNIKIKV*" gene 1786104..1788407 /gene="pksE" /locus_tag="BSU_17120" /old_locus_tag="BSU17120" CDS 1788469..1788717 /gene="acpK" /locus_tag="BSU_17130" /old_locus_tag="BSU17130" /function="16.5: Explore" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1c: Function from experimental evidences in the studied genus; PubMedId: 16707694, 16757561, 17234808, 26284661; Product type c: carrier" /codon_start=1 /transl_table=11 /product="acyl-carrier protein involved in bacillaene synthesis" /protein_id="NP_570904.1" /db_xref="EnsemblGenomes-Gn:BSU17130" /db_xref="EnsemblGenomes-Tr:CAE01454" /db_xref="GOA:Q7PC63" /db_xref="InterPro:IPR009081" /db_xref="InterPro:IPR036736" /db_xref="SubtiList:BG14186" /db_xref="UniProtKB/Swiss-Prot:Q7PC63" /translation="MDKQRIFEVLITNICEVLPELDGHRFEPEDQLVELGADSVDRAE IITMVLEDLSLKIPRIELSGVKNIGELAEVLYDKVQSA*" gene 1788469..1788717 /gene="acpK" /locus_tag="BSU_17130" /old_locus_tag="BSU17130" CDS 1788695..1789942 /gene="pksF" /locus_tag="BSU_17140" /old_locus_tag="BSU17140" /EC_number="2.3.1.-" /function="16.5: Explore" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:16757561, 17234808, 26284661" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16757561, 17234808, 26284661; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="decarboxylase converting malonyl-S-AcpK to acetyl-S-AcpK for bacillaene-related polyketide synthesis" /protein_id="NP_389594.2" /db_xref="EnsemblGenomes-Gn:BSU17140" /db_xref="EnsemblGenomes-Tr:CAB13585" /db_xref="GOA:P40804" /db_xref="InterPro:IPR014030" /db_xref="InterPro:IPR014031" /db_xref="InterPro:IPR016039" /db_xref="InterPro:IPR020841" /db_xref="SubtiList:BG10925" /db_xref="UniProtKB/Swiss-Prot:P40804" /translation="MTKCNLPEVVVTGVGVTASIGQGKEDFASSLLSGRHAFDVMKRS GRQKDSRFIGAEIASLSYPDRLSKKMLRKASFSSRAALVTLTEAWEEAELDDADSSRI GLVVGGSNFQQRENFEVYERYQDRSGFISPAYGLSFMDSDLCGICTDQFGITGLAYTV GGASASGQLAVIHAIQQVLSGEVDTCIALGALMDLSYMECEALRALGAMGTDKYADEP ENACRPFDQNRDGFIYGESCGALVIERKETALRRGLKPYAALSGWSIKLDGNRNPDPS LEGEIHVIQKALERARLLPEDIDYINPHGTGSFIGDEIELKALRACRLSHAYINATKS ITGHGLSAAGIVEIISVLLQMKKSALHPSRNLDHPIDDSFHWVNEKSISYRIKNALSL SMGFGGMNTAVCIQNIEKCGGES*" gene 1788695..1789942 /gene="pksF" /locus_tag="BSU_17140" /old_locus_tag="BSU17140" CDS 1789943..1791205 /gene="pksG" /locus_tag="BSU_17150" /old_locus_tag="BSU17150" /function="16.5: Explore" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1c: Function from experimental evidences in the studied genus; PubMedId: 16707694, 16757561, 17234808, 26284661; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="acetyl-S-AcpK beta-ketothioester bacillaene intermediate transferase" /protein_id="NP_389595.2" /db_xref="EnsemblGenomes-Gn:BSU17150" /db_xref="EnsemblGenomes-Tr:CAB13586" /db_xref="GOA:P40830" /db_xref="InterPro:IPR013528" /db_xref="InterPro:IPR013746" /db_xref="InterPro:IPR016039" /db_xref="PDB:4YXQ" /db_xref="PDB:4YXT" /db_xref="PDB:4YXV" /db_xref="SubtiList:BG10926" /db_xref="UniProtKB/Swiss-Prot:P40830" /translation="MVSAGIEAMNVFGGTAYLDVMELAKYRHLDTARFENLLMKEKAV ALPYEDPVTFGVNAAKPIIDALSEAEKDRIELLITCSESGIDFGKSLSTYIHEYLGLN RNCRLFEVKQACYSGTAGFQMAVNFILSQTSPGAKALVIASDISRFLIAEGGDALSED WSYAEPSAGAGAVAVLVGENPEVFQIDPGANGYYGYEVMDTCRPIPDSEAGDSDLSLM SYLDCCEQTFLEYQKRVPGANYQDTFQYLAYHTPFGGMVKGAHRTMMRKVAKVKTSGI ETDFLTRVKPGLNYCQRVGNIMGAALFLALASTIDQGRFDTPKRIGCFSYGSGCCSEF YSGITTPQGQERQRTFGIEKHLDRRYQLSMEEYELLFKGSGMVRFGTRNVKLDFEMIP GIMQSTQEKPRLFLEEISEFHRKYRWIS*" gene 1789943..1791205 /gene="pksG" /locus_tag="BSU_17150" /old_locus_tag="BSU17150" CDS 1791193..1791972 /gene="pksH" /locus_tag="BSU_17160" /old_locus_tag="BSU17160" /function="16.5: Explore" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1c: Function from experimental evidences in the studied genus; PubMedId: 16707694, 16757561, 17234808, 26284661; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="enoyl-CoA hydratase for bacillaene biosynthesis" /protein_id="NP_389596.1" /db_xref="EnsemblGenomes-Gn:BSU17160" /db_xref="EnsemblGenomes-Tr:CAB13587" /db_xref="GOA:P40805" /db_xref="InterPro:IPR001753" /db_xref="InterPro:IPR018376" /db_xref="InterPro:IPR029045" /db_xref="PDB:3HP0" /db_xref="SubtiList:BG10927" /db_xref="UniProtKB/Swiss-Prot:P40805" /translation="MDLVTYQTIKVRFQASVCYITFHRPEANNTINDTLIEECLQVLN QCETSTVTVVVLEGLPEVFCFGADFQEIYQEMKRGRKQASSQEPLYDLWMKLQTGPYV TISHVRGKVNAGGLGFVSATDIAIADQTASFSLSELLFGLYPACVLPFLIRRIGRQKA HYMTLMTKPISVQEASEWGLIDAFDAESDVLLRKHLLRLRRLNKKGIAHYKQFMSSLD HQVSRAKATALTANQDMFSDPQNQMGIIRYVETGQFPWEDQ*" gene 1791193..1791972 /gene="pksH" /locus_tag="BSU_17160" /old_locus_tag="BSU17160" CDS 1792012..1792761 /gene="pksI" /locus_tag="BSU_17170" /old_locus_tag="BSU17170" /function="16.5: Explore" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1c: Function from experimental evidences in the studied genus; PubMedId: 16707694, 16757561, 17234808, 22720735, 26284661; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="decarboxylase involved in bacillaene synthesis" /protein_id="NP_389597.2" /db_xref="EnsemblGenomes-Gn:BSU17170" /db_xref="EnsemblGenomes-Tr:CAB13588" /db_xref="GOA:P40802" /db_xref="InterPro:IPR001753" /db_xref="InterPro:IPR018376" /db_xref="InterPro:IPR029045" /db_xref="PDB:4Q1G" /db_xref="PDB:4Q1H" /db_xref="PDB:4Q1I" /db_xref="PDB:4Q1J" /db_xref="PDB:4Q1K" /db_xref="SubtiList:BG10928" /db_xref="UniProtKB/Swiss-Prot:P40802" /translation="MTHSVVELIEIESAIIQVKMQDRTHKNAFSQELTDDLIQAFEYI RQNPKYKAVILTGYDNYFASGGTQEGLLRIQQGLTKFTDDNLYSLALDCEIPVIAAMQ GHGIGGGFVMGLFADIVILSRESVYTANFMKYGFTPGMGATFIVPKKLGFSLAQEILL NAGSYRGADLEKRGVPFKVLPRAEVLDYAVELAQELAEKPRNSLVTLKDHLVAPLRDQ LPRVIEQELMMHEKTFHHEEVKSRIKGLYGN*" gene 1792012..1792761 /gene="pksI" /locus_tag="BSU_17170" /old_locus_tag="BSU17170" CDS 1792806..1807937 /gene="pksJ" /locus_tag="BSU_17180" /old_locus_tag="BSU17180" /function="16.8: Protect" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1c: Function from experimental evidences in the studied genus; PubMedId: 16707694, 17234808, 17827323, 26284661, 26268540; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="polyketide synthase of type I involved in nonribosomal synthesis of bacillaene" /protein_id="NP_389598.3" /db_xref="EnsemblGenomes-Gn:BSU17180" /db_xref="EnsemblGenomes-Tr:CAB13589" /db_xref="GOA:P40806" /db_xref="InterPro:IPR000873" /db_xref="InterPro:IPR001242" /db_xref="InterPro:IPR006162" /db_xref="InterPro:IPR009081" /db_xref="InterPro:IPR010071" /db_xref="InterPro:IPR013968" /db_xref="InterPro:IPR014030" /db_xref="InterPro:IPR014031" /db_xref="InterPro:IPR016039" /db_xref="InterPro:IPR018201" /db_xref="InterPro:IPR020806" /db_xref="InterPro:IPR020807" /db_xref="InterPro:IPR020841" /db_xref="InterPro:IPR020845" /db_xref="InterPro:IPR025110" /db_xref="InterPro:IPR032821" /db_xref="InterPro:IPR036291" /db_xref="InterPro:IPR036736" /db_xref="PDB:4J1Q" /db_xref="PDB:4J1S" /db_xref="PDB:4NA1" /db_xref="PDB:4NA2" /db_xref="PDB:4NA3" /db_xref="PDB:5KTK" /db_xref="SubtiList:BG10929" /db_xref="UniProtKB/Swiss-Prot:P40806" /translation="MRNNDNIRILTNPSVSHGEPLHISEKQPATIPEVLYRTATELGD TKGIIYLQPDGTEVYQSYRRLWDDGLRIAKGLRQSGLKAKQSVILQLGDNSQLLPAFW GCVLTGVVPAPLAVPPTYAESSSGTQKLKDAWTLLDKPAVITDRGMHQEMLDWAKEQG LEGFRAIIVEDLLSAEADTDWHQSSPEDLALLLLTSGSTGTPKAVMLNHRNIMSMVKG IIQMQGFTREDITFNWMPFDHVGGIGMLHLRDVYLGCQEINVSSETILMEPLKWLDWI DHYRASVTWAPNFAFGLVTDFAEEIKDKKWDLSSMRYMLNGGEAMVAKVGRRILELLE PHGLPADAIRPAWGMSETSSGVIFSHEFTRAGTSDDDHFVEIGSPIPGFSMRIVNDHN ELVEEGEIGRFQVSGLSVTSGYYQRPDLNESVFTEDGWFETGDLGFLRNGRLTITGRT KDAIIINGINYYSHAIESAVEELPEIETSYTAACAVRLGQNSTDQLAIFFVTSAKLND EQMSQLLRNIQSHVSQVIGVTPEYLLPVQKEEIPKTAIGKIQRTQLKTSFENGEFDHL LHKPNRMNDAVQDEGIQQADQVKRVREEIQKHLLTCLTEELHVSHDWVEPNANIQSLG VNSIKMMKLIRSIEKNYHIKLTAREIHQYPTIERLASYLSEHEDLSSLSADKKGTDTY KTEPERSQATFQPLSEVQKGLWTLQKMSPEKSAYHVPLCFKFSSGLHHETFQQAFGLV LNQHPILKHVIQEKDGVPFLKNEPALSIEIKTENISSLKESDIPAFLRKKVKEPYVKE NSPLVRVMSFSRSEQEHFLLVVIHHLIFDGVSSVTFIRSLFDTYQLLLKGQQPEKAVS PAIYHDFAAWEKNMLAGKDGVKHRTYWQKQLSGTLPNLQLPNVSASSVDSQFREDTYT RRLSSGFMNQVRTFAKEHSVNVTTVFLSCYMMLLGRYTGQKEQIVGMPAMVRPEERFD DAIGHFLNMLPIRSELNPADTFSSFISKLQLTILDGLDHAAYPFPKMVRDLNIPRSQA GSPVFQTAFFYQNFLQSGSYQSLLSRYADFFSVDFVEYIHQEGEYELVFELWETEEKM ELNIKYNTGLFDAASISAMFDHFVYVTEQAMLNPSQPLKEYSLLPEAEKQMILKTWNA TGKTYPYITFHELFEQQAKKTPDRAAVSYEGQTLTYRELDEKSTQLAIYLQAHGVGPD RLAGIYVDRSLDMLVGLLAILKAGGAYVPLDPSYPAERLEYMLEDSEVFITLTTSELV NTLSWNGVTTALLDQDWDEIAQTASDRKVLTRTVTPENLAYVIYTSGSTGKPKGVMIP HKALTNFLVSMGETPGLTAEDKMLAVTTYCFDIAALELFLPLIKGAHCYICQTEHTKD VEKLKRDIRAIKPTVMQATPATWKMLFYSGWENEESVKILCGGEALPETLKRYFLDTG SEAWNMFGPTETTIWSAVQRINVECSHATIGRPIANTQIYITDSQLAPVPAGVPGELC IAGDGVAKGYYKKEELTDSRFIDNPFEPGSKLYRTGDMARWLTGGRIEYIGRIDNQVK IRGFRIELGDIESRLSEHPGILECVVVADMDNLAAYYTAKHANASLTARELRHFVKNA LPAYMVPSYFIQLDHMPLTPNGKIDRNSLKNIDLSGEQLKQRQTSPKNIQDTVFTIWQ EVLKTSDIEWDDGFFDVGGDSLLAVTVADRIKHELSCEFSVTDLFEYSTIKNISQYIT EQRMGDASDHIPTDPAAHIEDQSTEMSDLPDYYDDSVAIIGISCEFPGAKNHDEFWEN LRDGKESIAFFNKEELQRFGISKEIAENADYVPAKASIDGKDRFDPSFFQISPKDAEF MDPQLRMLLTHSWKAIEDAGYAARQIPQTSVFMSASNNSYRALLPSDTTESLETPDGY VSWVLAQSGTIPTMISHKLGLRGPSYFVHANCSSSLIGLHSAYKSLLSGESDYALVGG ATLHTESNIGYVHQPGLNFSSDGHIKAFDASADGMIGGEGVAVVLLKKAADAVKDGDH IYALLRGIGVNNDGADKVGFYAPSVKGQADVVQQVMNQTKVQPESICYVEAHGTGTKL GDPIELAALTNVYRQYTNKTQFCGIGSVKTNIGHLDTAAGLAGCIKVVMSLYHQELAP SVNYKEPNPNTDLASSPFYVVDQKKTLSREIKTHRAALSSFGLGGTNTHAIFEQFKRD SDKGKIDGTCIVPISAKNKERLQEYAEDILAYLERRGFENSQLPDFAYTLQVGREAME HRVVFIADHVNELKQRLTDFINGNTAIEGCFQGSKHNAREVSWLTEDEDSAELIRKWM AKGKVNKLAEMWSKGAHIDWMQLYKGERPNRMSLPTYPFAKERYWPSQDDRKPVAQIS GNQTGIGSIHPLLHQNTSDFSEQKFSSVFTGDEFFLRDHVVRGKPVLPGVAYLEMAYA AINQAAGSEIGQDVRIRLNHTVWVQPVVVDRHSAQVDISLFPEEDGKITFDIYSTQED GDDPVIHSQGSAELASAAETPVADLTEMSRRCGKGKMSPDQFYEEGRSRGMFHGPAFQ GIKNVNIGNREVLAQLQLPEIVSGTNEQFVLHPSIMDSALQTATICIMQELTDQKLIL PFALEELEVIKGCSSSMWAYARLSDSDHSGGVVQKADIDVIDESGTVCVRIKGFSTRV LEGEVHTSKPSTRHERLMLEPVWEKQNEEREDEDLSYTEHIIVLFETERSVTDSIASH MKDARVITLNEAVGHIAERYQCYMQNIFELLQSKVRKLSAGRIIIQAIVPLEKEKQLF AGVSGLFKTAEIEFSKLTAQVIEIEKPEEMIDLHLKLKDDSRRPFDKQIRYEAGYRFV KGWREMVLPSADTLHMPWRDEGVYLITGGAGSLGLLFAKEIANRTGRSTIVLTGRSVL SEDKENELEALRSIGAEVVYREADVSDQHAVRHLLEEIKERYGTLNGIIHGAGSSKDR FIIHKTNEEFQEVLQPKVSGLLHVDECSKDFPLDFFIFFSSVSGCLGNAGQADYAAAN SFMDAFAEYRRSLAASKKRFGSTISFNWPLWEEGGMQVGAEDEKRMLKTTGMVPMPTD SGLKAFYQGIVSDKPQVFVMEGQLQKMKQKLLSAGSKAKRNDQRKADQDQGQTRKLEA ALIQMVGAILKVNTDDIDVNTELSEYGFDSVTFTVFTNKINEKFQLELTPTIFFEYGS VQSLAEYVVAAYQGEWNQDATAKGKDERTNLVHSLSSLEASLSNMVSAILKVNSEDID VNTELSEYGFDSVTFTVFTNKINEEFQLELTPTIFFEYGSLHSLAEYLTVEHGDTLVQ EREKPEGQEELQTKSSEAPKITSRRKRRFTQPIIAKAERNKKQAADFEPVAIVGISGR FPGAMDIDEFWKNLEEGKDSITEVPKDRWDWREHYGNPDTDVNKTDIKWGGFIDGVAE FDPLFFGISPREADYVDPQQRLLMTYVWKALEDAGCSPQSLSGTGTGIFIGTGNTGYK DLFHRANLPIEGHAATGHMIPSVGPNRMSYFLNIHGPSEPVETACSSSLVAIHRAVTA MQNGDCEMAIAGGVNTILTEEAHISYSKAGMLSTDGRCKTFSADANGYVRGEGVGMVM LKKLEDAERDGNHIYGVIRGTAENHGGRANTLTSPNPKAQADLLVRAYRQADIDPSTV TYIEAHGTGTELGDPIEINGLKAAFKELSNMRGESQPDVPDHRCGIGSVKSNIGHLEL AAGISGLIKVLLQMKHKTLVKSLHCETLNPYLQLTDSPFYIVQEKQEWKSVTDRDGNE LPRRAGISSFGIGGVNAHIVIEEYMPKANSEHTATEQPNVIVLSAKNKSRLIDRASQL LEVIRNKKYTDQDLHRIAYTLQVGREEMDERLACVAGTMQELEEKLQAFVDGKEETDE FFRGQSHRNKETQTIFTADEDMALALDAWIRKRKYAKLADLWVKGVSIQWNTLYGETK PRLISLPSYPFAKDHYWVPAKEHSERDKKELVNAIEDRAACFLTKQWSLSPIGSAVPG TRTVAILCCQETADLAAEVSSYFPNHLLIDVSRIENDQSDIDWKEFDGLVDVIGCGWD DEGRLDWIEWVQRLVEFGHKEGLRLLCVTKGLESFQNTSVRMAGASRAGLYRMLQCEY SHLISRHMDAEEVTDHRRLAKLIADEFYSDSYDAEVCYRDGLRYQAFLKAHPETGKAT EQSAVFPKDHVLLITGGTRGIGLLCARHFAECYGVKKLVLTGREQLPPREEWARFKTS NTSLAEKIQAVRELEAKGVQVEMLSLTLSDDAQVEQTLQHIKRTLGPIGGVIHCAGLT DMDTLAFIRKTSDDIQRVLEPKVSGLTTLYRHVCNEPLQFFVLFSSVSAIIPELSAGQ ADYAMANSYMDYFAEAHQKHAPIISVQWPNWKETGMGEVTNQAYRDSGLLSITNSEGL RFLDQIVSKKFGPVVLPAMANQTNWEPELLMKRRKPHEGGLQEAALQSPPARDIEEAD EVSKCDGLLSETQSWLIDLFTEELRIDREDFEIDGLFQDYGVDSIILAQVLQRINRKL EAALDPSILYEYPTIQRFADWLIGSYSERLSALFGGRISDASAPLENKIEAEASVPGK DRALTPQIQAPAILSPDSHAEGIAVVGLSCRFPGAETLESYWSLLSEGRSSIGPIPAE RWGCKTPYYAGVIDGVSYFDPDFFLLHEEDVRAMDPQALLVLEECLKLLYHAGYTPEE IKGKPVGVYIGGRSQHKPDEDSLDHAKNPIVTVGQNYLAANLSQFFDVRGPSVVVDTA CSSALVGMNMAIQALRGGDIQSAIVGGVSLLSSDASHRLFDRRGILSKHSSFHVFDER ADGVVLGEGVGMVMLKTVKQALEDGDIIYAVVKAASVNNDGRTAGPATPNLEAQKEVM KDALFKSGKKPEDISYLEANGSGSIVTDLLELKAIQSVYRSGHSSPLSLGSIKPNIGH PLCAEGIASFIKVVLMLKERRFVPFLSGEKEMAHFDQQKANITFSRALEKWTDSQPTA AINCFADGGTNAHVIVEAWEKDEKHAIKRSPISPPQLKKRMLSPGEPKLEAETSKMTA ANIWDTYEVEV*" gene 1792806..1807937 /gene="pksJ" /locus_tag="BSU_17180" /old_locus_tag="BSU17180" promotor_-10 complement(1797651..1797670) /Source="Nicolas_upshift_promotors" /id="U1371" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.993006993006993" /psig="0.993006993006993" /xcortree=1370 /SigmaFactorBS="ttcttaaggctgtttctatctatctttccgttcgGAGTTAAC GGcatatgatcaagcTGAATAAAATAAGAAGGCACcatataggcaggcaaagcgtttt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1797667) /Source="Nicolas_upshifts" /id="U1371" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.993006993006993" /psig="0.993006993006993" /xcortree=1370 /SigmaFactorBS="ttcttaaggctgtttctatctatctttccgttcgGAGTTAAC GGcatatgatcaagcTGAATAAAATAAGAAGGCACcatataggcaggcaaagcgtttt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(1797684..1797693) /Source="Nicolas_upshift_promotors" /id="U1371" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.993006993006993" /psig="0.993006993006993" /xcortree=1370 /SigmaFactorBS="ttcttaaggctgtttctatctatctttccgttcgGAGTTAAC GGcatatgatcaagcTGAATAAAATAAGAAGGCACcatataggcaggcaaagcgtttt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" CDS 1807921..1821537 /gene="pksL" /locus_tag="BSU_17190" /old_locus_tag="BSU17190" /function="16.5: Explore" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1c: Function from experimental evidences in the studied genus; PubMedId: 16707694, 16757561, 17234808, 22720735, 26284661; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="polyketide synthase of type I (bacillaene synthesis)" /protein_id="NP_389600.3" /db_xref="EnsemblGenomes-Gn:BSU17190" /db_xref="EnsemblGenomes-Tr:CAB13602" /db_xref="GOA:Q05470" /db_xref="InterPro:IPR006162" /db_xref="InterPro:IPR009081" /db_xref="InterPro:IPR011254" /db_xref="InterPro:IPR013968" /db_xref="InterPro:IPR014030" /db_xref="InterPro:IPR014031" /db_xref="InterPro:IPR016039" /db_xref="InterPro:IPR018201" /db_xref="InterPro:IPR020806" /db_xref="InterPro:IPR020807" /db_xref="InterPro:IPR020841" /db_xref="InterPro:IPR032821" /db_xref="InterPro:IPR036291" /db_xref="InterPro:IPR036736" /db_xref="PDB:5E1V" /db_xref="PDB:5E5N" /db_xref="PDB:5E6K" /db_xref="PDB:5ENY" /db_xref="PDB:5ERF" /db_xref="SubtiList:BG10698" /db_xref="UniProtKB/Swiss-Prot:Q05470" /translation="MRWRSNVKKITKQLTLSLKNPFIYHHVVYGQNVLPGLAYIDIIY QIFREHGFSCSELQLRNLSIYQPLTAEQDAVIVLNIQCAEKKEGQWQITAKGIEKRDG KEASEEKLYMKADMHADSPAIFEETLDLSQIKASAQNVVQLDDVYEQCRRQELVHSEY MKAKGCIYEEEDGVLLELSLGSEAMLHAEGFMFHPTLIDGSGVGANHLLTSLLKGEQR LYLPLFYESFSASALLQTDCMTRIKRSSVRREKELIYVTLEFFNASGEKVAELKNFTS KLVREAELISGKHQDAQETQMTRADTAERDKPADMVSSPVNSYSEAEQFVSQLIAEKI NKPVEQVEKQVGYYQMGLNSSGLLEVVETISDKIGESLSPTLLFEHTTIAELSAFLAE EYAEHFSAAGSLGQNERARVSDSINDHKTVEGSRPAPIEAAGDIAIIGLAGRYPKAAN IHEFWNNLKEGKDCVSEIPESRWDWQRLEGITSPSGKDISKWGGFIDDPDCFDPQFFR ITPREAETMDPQERLFLETCWETIEDAGYTPKTLAKPKGRNKRQHVGVFAGVMHKDYT LVGAEEASAENVFPLSLNYAQIANRVSYFCNFHGPSMAVDTVCSSSLTAVHLALESIR HGECDVALAGGVNLSLHPNKYMTYGVWDMFSTDGHCRTFGKDGDGYVPAEGIGAVLLK PLRQAEEDGDRIYAVIKGSAVNHVGTVSGISVPSPVSQADLIETCLEKTGIDPRTISY VEAHGTGTSLGDPIEIQGLVKAFRQYTQDRQFCSIGSVKSNIGHAESAAGISGLSKVA LQLHHQKLVPSLHSEELNPYVDFEKSPFYVQHETETWKQPVIKENGEDVPYPRRAGIS SFGATGSNAHIILEEHIPQAAEQDVSLSSDSDISAVIPLSARNQERLRVYAKRLLDFL HDGIQIRDLAYTLQVGREPMEERVSFLASGIQELSDQLKAFIEGRKAIQHCWKGRVSR GSEPSRPAESVHKLLEQRKLDQIAEQWANGSGVDWKLLYEGSKPKRISLPTYPFERVR YWVPKAEKKTDRSKQERHILHPLLHQNVSDISGVRFRSAFTGREFFLKDHVIKGEHVL PGAALLEMVRAAVERAAADQFPTGFRLRNIVWVRPFAVTEQQKDIDVRLYPEENGEIT FEICRDPESAEESPIVYGQGSAVLCEAGENPVINIEELKASYNGRTLSPFDCYEAYTE MGIHYGDSHRAIDSLYAGENGVLVKLTMPPVISDTEDHYILHPSMIDSAFQASIGLRL GGATSLEDRKAMLPFAIQDVRIFKGCEASMWARITYSEGSTAGDRMQKLDIDLCNEEG QVCVRLTSYSARVLETDQEGPSEANDTLLFEHIWEERAAERQELIEYDTYKVVVCDVG EQMESLQNHLDCTVLQHDTETIDERFEGYAIQLFEEIKQLMHSKTGGHTFIQVAVPAL DEPQLLSGLTGLLKTAELENPKLTGQLIEIETGMSAGELFEILEENRRYPRDTHIRHW QGKRFVSKWKEVSGEHLSADMPWKDKGVYLITGGAGGLGFIFATEIANQTNDAVVILT GRSPLDERKKKKLKALQKLGIQAIYRQADLADKQTVDALLKETQNVYGDLDGIIHSAG LIKDNFIMKKKKEEVQTVLAPKVAGLIHLDEATKDIPLDFFILFSSGAGAVGSAGQAD YAMANAFMNAFSEYRNGQAELHKRYGKTLSVCWPLWKDGGMQIDAETARMLKRETGMV AMETDRGIQALYHGWTSGKPQVLVASGVTDRIRAFLHETGHGKGQSHNIKKSSLNQEA EKADMIGEIDEEILREKAENYFKQVLSSVIKLPAGQIDAEAPLEDYGIDSIMIMHVTG QLEKVFGSLSKTLFFEYQDIRSLTRYFIDSRREKLLDILGFETGKPSVERKSEPEKQE IPVIPRKSGFLPLQDKEQKQVREKETEEIAIIGISGRYPQADNIDELWEKLRDGRDCI TEIPADRWDHSLYYDEDKDKPGKTYSKWGGFMKDVDKFDPQFFHISPREAKLMDPQER LFLQCVYETMEDAGYTREHLGRKRDAELGGSVGVYVGVMYEEYQLYGAQEQVRGRSLA LTGNPSSIANRVSYYFDFHGPSIALDTMCSSSLTAIHLACQSLQRGECEAAFAGGVNV SIHPNKYLMLGQNKFMSSKGRCESFGQGGDGYVPGEGVGAVLLKPLSKAVEDGDHIYG IIKGTAINHGGKTNGYSVPNPNAQADVIKKAFVEAKVDPRTVSYIEAHGTGTSLGDPI EITGLSKVFTQETDDKQFCAIGSAKSNIGHCESAAGIAGVTKVLLQMKYRQLAPSLHS NVLNPNIDFLNSPFKVQQELEEWKRPIISVNGKDIELPRIAGVSSFGAGGVNAHILIE EYAPEPVEERLPARKQPAVIVLSAKNEERLQKRAERLLHAIREQTYVEADLHRIAYTL QVGREAMKERLAFVAETMQELEEKLYECISGTENREYVYRGQVKSNKEAIAAFAADED MSKTIEAWLQKGKYAKVLDLWVRGLRIDWSTLYQDQKPRRISLPAYPFARDRYWIDVN AKAEEKRTEEPFAPVQPVIPKPSVDREASGKPANITLQPLMTNQDRLERVPSDTETET ITAEALCDELTAGLAEVLYMDQNEIDPDEAFIDIGMDSITGLEWIKAINKQYGTSLNV TKVYDYPTTRDFAVYLAHELSTQAGEKKQTETYTPIRQKTVVPAAKPANISLQPLEHH QPVQEEAEETIQYAAAEISASRQYTVAIETLHENLRESIADVLYMEPYEVDIDEAFID IGMDSITGLEWIKAVNKQYGTSFTVTRVYDYPTIRDFAEMLKSELGTHLDRKIEHTDS FEAAQQKPAASSHPKPAERPLQPVQHPIKKEHEKKTVPVLQDRPEDAIAIVGMSGRYP GARNVREYWDNLVHARNAIRDIPTSRWDVDKYYDPVLNKKGKVYCKSMGMLDDIEHFD PLFFNIPPSEAELMDPQHRIFLQEGYKAFEDAGYNARTLNEKKCGVYLGIMSNEYGVM LNRQSRANATGNSFAIAAARIPYFLNLKGPAIPIDTACSSSLVGTHLARQALINKEID MALVGGVSLYLTPESYMSMCEAGMLSPDGQCKAFDNGANGFVPGEGAGALVLKRLKDA EADRDHIYGIIIGSGINQDGKTNGITAPSAKSQMDLERDIYETYGIHPESISYVEMHG TGTKQGDPIELEALSTVFQEKTDKKQFCAIGSVKSNIGHTSAAAGVAGVQKVLLCMNH KTLVPTLNFTTPNEHFEFEHSPLYVNTELKPWETADGKPRRACVSSFGYSGTNAHIVI EEYQPEKRNDRLTKQHRSALFVLSAKKEKQLKAYAEAMKDFVTSNEDIDLEDMAYTLQ TGREAMDYRMAFLADSREMLIKALDDYLAEMPNGSIFAAHVKTKKSEIKLFETDHDAK ALLQTWIEKKRLEKVAELWVKGLQIDWNKLYGEYTPRRISLPAYPFAEEYYWLPTQEG EPETIATAMPQFELMPKRCFLRKQWQPCPIEPAEMTNQTVAILANEETMALAEELSAY FSTYRIFDSQELDRVSAADYEHVAGAIDLIGCGTSHEHSMGWINWLQKLIEQGRASKH HLTVLGVTKGLEAYANEGVLLSGASRAGLYRMLQSEYSHLTSRHADMECEASHEELAR LIAVEYYAKSTESEVCYRNGQRYRAYLTEQPAEAALSHKQVSFSTDKVLLITGGTRGL GLLCARHFVKTYGVKRLVLIGREELPPRDQWNSVKISSLAEKIKAVQELEDMGAQVQV LSLDLTDRVAVEQSLKTIHETMGAIGGVIHCAGMVNKQNPAFIRKSLEEIGQVLEPKV EGLQTLFDLLQDEPLAFFTLFSSVSAAIPALAAGQADYAMANAFMDYFAEAHQDKCPI VSIQWPNWKETGLGEVRSKALEQTGLISLTNDEGLQLLDQILSDRQYAVVLPAVPDTN VWKPDKLMQPSLPVEALSHPETKEQTSTRNLFPETVDWLVTLFSDELKIAAEDFETDE PFQEYGIDSIILAQLVQQMNQQLNGDIDPSILFEYPTIESFAHWLISKYDISAVLQPS VPEKQTPLKPQSAMKQKLVPEQRPQQISHEKTALLAEDIAIIGLSCRFPGAETLEEYW DLIRDGRSAIAPVPPERFGNSSSNYAGLIDEMNRFDHDFFMMSESDVRAMDPQALAVL EESLKLWYHAGYTEKEVKGMRAGVYIGGRSQHKPDPASLSKAKNPIVAGGQNYLAANI SQFFDLKGPSIVLDTACSSALVGLNMAIQALRSGDIEAAVVGGVSLLDADAHRMFHER GLLCDKPSFHIFDKRADGVILGEGVGMVLVKTVNQAVEDGDSIYAVIKAAAINNDGRT AGPSSPNLEAQKDVMLSALEKSGKKTEEISYLEANGSGSAVTDLLELKAIQSIYRSES KAPLGLGSVKPNIGHPLCAEGIASLIKVALMLKHRQLVPFLSGNENMPYFDIEKTDLY FSRSQAEWKETTPAAAINCFADGGTNAHLIIEGWRDSAERPIRRKPLPLPELNRQPVL IKPSAQNVQKKVHSDTGASKDMFWKTFK*" gene 1807921..1821537 /gene="pksL" /locus_tag="BSU_17190" /old_locus_tag="BSU17190" CDS 1821553..1834341 /gene="pksM" /locus_tag="BSU_17200" /old_locus_tag="BSU17200" /function="16.5: Explore" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:15480790, 16707694, 17234808, 26284661" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15480790, 16707694, 17234808, 26284661; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="trans AT polyketide synthase of type I involved in bacillaene synthesis" /protein_id="NP_389601.3" /db_xref="EnsemblGenomes-Gn:BSU17200" /db_xref="EnsemblGenomes-Tr:CAB13603" /db_xref="GOA:P40872" /db_xref="InterPro:IPR006162" /db_xref="InterPro:IPR009081" /db_xref="InterPro:IPR013217" /db_xref="InterPro:IPR013968" /db_xref="InterPro:IPR014030" /db_xref="InterPro:IPR014031" /db_xref="InterPro:IPR016039" /db_xref="InterPro:IPR018201" /db_xref="InterPro:IPR020615" /db_xref="InterPro:IPR020806" /db_xref="InterPro:IPR020807" /db_xref="InterPro:IPR020841" /db_xref="InterPro:IPR029063" /db_xref="InterPro:IPR032821" /db_xref="InterPro:IPR036291" /db_xref="InterPro:IPR036736" /db_xref="SubtiList:BG10931" /db_xref="UniProtKB/Swiss-Prot:P40872" /translation="MITEQLHISLNNPIMSNHKVYGQALLPGLAYIDLIYQVFQEHGY AYQELELKNLTIFYPLIADESYDIALTIHVSERKEGTWSIIIDGQKQHGESLSDKRQY VTADMHRKEQTAFAESIDLNQWKSTADRILNLDEIYEQCRSQELVHTGMMKAEGQIYE AKEGAVIDLAVGQEALRHSDAFLFHPTLIDGSGIGSSCLISDQTMYLPLYYESFSASE RLQKGCTARILSSSVRQKKELTYMTIEYFNSAGQKVAELKQFAGKSVRNMSAFHSAKE IQEERAAVSQNISRDYPAFEMYLRQLLAKQLERPAEQMDIHAGYYELGLDSSSLLTVV QEIGDKVGADLAPTLLFEFTTIAELAAHLADHYSIGEADDAVRQSPSPIDGVTSSPEI GEDIAIIGMAGRYPKAKNIQEFWEQLKAGTDCITEIPNSRWEWKESDGLDSPAGKPLS KWGGFIEEADCFDPQFFRISPREAEMMDPQERLFLETCWEAIEDAGYTPETIASPQGE NKRQHVGVFAGVMHKDYSLIGAEALSEHNPFPLSLNYAQIANRVSYYCNFHGPSMAVD TVCSSSLTAVHLAIESIRNGECEAALAGGVNLSLHPAKYISYGSVGMHSSDGYCHTFG KGGDGYVSGEGVGTVLLKPLRKAEQDGDRIYAVIKGSAINHVGKVSGITVPSPVAQAD VIEACLEKTGIDPRTISYVEAHGTGTSLGDPIEVQGLVKAFSRNTQDKQFCSIGSVKS NIGHAEAAAGISGLTKTVLQLHHKTLVPSLHSEELNPYLKLDQTPFFVQHETKEWEQP SFTENGVDVTYPRRAGLSSFGASGSNAHLILEEYIPAESHSETILTKNEEIVIPLSAR NKDRLQAYALKLLDFLSEDVNLLALAYTMQAGRVEMEERAAFIVKDIKDLTAKLRAFA NGEEEIEGCWTGRAKENQEAAGLASVNALNNNLIRDSEMMEMAKAWVQGKRVTWDDLY GDRKPLKISVPTYPFARERYWISVPEMKTSTVNHILHPLVHRNTSDFTEQRFSSVFTG TEFFLSDHVVQGQKILPGVAYLEMAREAAEKAAGDLDGEQRVVSLKDIVWVRPITIES EPKEIHIGLFPEDNGDISFDIYSSSEHKEEALTIHCQGRAVISDEAETSILNLSSIQT ECSLDTVTSEQCYAAFRKIGLDYGEGYQGIEKVYVGKDQLLAKISLPAFLKNDKQHFA LHPSLMDSAFHATVGFIVSSVNAAGQAQTLSLPFALQEVDIFSPCPEKIWSYIRYSSD SKAENKVRKYDIDLCDENGRVCVRMKGASMRALDGEQHSKPQLLTDSQLTGHTVMIPV WEPVSLEAEDNASFAGKRAVLCGAAEADRTFIKHHYPQISFVDIRPADDIEAIADKLQ AYGSIDHVLWIAPSHRGSIGSDGQEEAVLHLFKLVKACLQLGYGEKQLEWSLVTVQAQ PVTQHEAVQPAHASIHGLAGTMAKEYPHWKIRLLDLEKGCTWPVNHMFALPADRLGHA WAYRNQQWHQQQLIPYRSSLSGDTLYRKGGVYVVIGGAGYIGEAWSEYMIRRYQAQIV WIGRSQLNAAIQSKIDRLSALGPEPFYIAADAADKHSLQQAYEQVKKRHPHIHGIVHS AMVLFEQSLEKMKPEEFTAGLAAKIDVSIRMAQVFRQENVDFVLFFSSLVAHIKNVKQ SHYASGCTFADAFAHQLSQSWACPVKVMNWGYWGNSEAAEDEHYVQLMNQIGLGLIEP AEAMKALEALLSGPVSQTAFIHTTKPVAVEGVNQNEFITLYPEQPSADAESLMERLPT TGRFQRVTHEELDDLLYRLLLGQLQTAELFDGYTLSVERLQQYKTREFYGKWIRQSSE FLLQHGYLKKVGDSLVRKDQAEDIELLWLEWNAKKEKWLKDSETKAMVVLAEAMLQAL PDILTGKVPATDIMFPHSSMELVEGIYKHNQVADYFNKVLADTLLAYLDERLKHDPEA SIRIMEIGAGTGGTSAGIFEKLKPYQKHINEYCYTDLSKAFLLHAEKEYGAENPYLTY QLFDVEKPIDQQEFEAGGYDVVIAANVLHATKNIRQTLRHTKAVMKNNGMLLLNEMAG NSLFPHITFGLLEGWWLYEDPAVRIPGCPGLHPDSWKAALESEGFESVFFPAEAAHDL SHQIVAASSNGLVRRMMKNVILPEKVVSQASNQEPAYIHTIDSEEAGQSKHALLREKS TEYMKKLIGETLKIPAGKIESSEPLEKYGIDSIVVVQLTNTLRKEFDHVSSTLFFEYQ TIDALVEHFIKTKTEALMKLTGLDRQVQQHTPAESRTQSSQKPDQAAKRTRRFRKLGF SGEKETPTNTLASRDVAVIGISGRYPQAETAEDFWNNLKEGRNCIEEIPKDRWDWKAY YDKEKGKEGSIYTKWGGFIKDMDKFDPLFFQISPLEAERMDPQERLFLQTAYASIEDA GYTPDSLCSSRKIGVFAGVMNKNYPTGYGYWSIANRISYLLNFQGPSLAVDTACSSSL TAIHLALESIYSGSSDCAIAGGVNLVVDPVHYQNLSVMNMLSASDTCKSFGDDADGFV DGEGVGAIVLKPLQQAIADGDHIYGVIKASAINSGGKTNGYTVPNPHAQAQVIKEAIE RADIPARTISYLEAHGTGTALGDPIEIAGLTKAFEKDTQEKQFCAIGSSKSNIGHCES AAGIAGLTKILFQFKYGQIAPSLHAQRLNPNIEFSHTPFVVQQQLGEWKRPVIGGQEV PRRAGLSSFGAGGSNAHIILEEYIPRTGAQTPKDHPPALIVLSAKNMERLQEKAEQLL TAIKQKRYCETDLIRIAYTLQTGREAMEERLAFIAESLEDLERKLNDFIENKADSLYL DRIDDNKKALAVLSADEDTEKIIEAWMSKGKYTKLLDLWVKGLSFDWGMLYGTQTPVR ISLPAYPFAKERYWAPGAAKAPVSIEQDHDQQTEEPFKVMTFQEVWKEEPATLTSKRI KTLICFLTEREKQNAFASALKNVDQDTKVIFISQGEVYSKQSEYSYQIVRQEPVTFEK AFQSIKEELGEPDAILYMWPMEDKRCIKDHSCIVYLLQGMSAAKLHPSRLLLAGCFED SLDRSYLESWIGFERSLGLVLPHTKVTGIFQPAEQGSMDDWTRKVWAELQASTEQTVL YQNLKRYVNHIEQTTIQPDNSKLKSGGTYLITGGVGGLGYLFAKHLAKNYAANLILTG RSPFNDEKQKQIKELKDLGGEAMYAEADVSDPIAMGDCVKRGKDRFGAINGVIHAAGI ESDSAIFDKKIESFQRIIEPKINGTIALDEWLKNEDLDFMCYFSSSSAVLGDFGCCDY AIGNRFQMAYAQYRNELHNGKTFVINWPVWKDGGMKIGDEETTDMYLKSSGQRFLEAE EGIRMFEHILAQQDAQHLVIAGQPSRVSRFLGMTEPAIPEPATQAPLAQENKDEVKTL SIEKRLEHDLKEHIHTLLKISKDKLNLNKNWADFGFDSIYLAKFSNVLSKHFNIEVTP ALFFGYSTLQELISFFLTDHKELIEAFYRDDASEAQKPPEAYAVIPVALEPEASKKSI RQVHDEPIAIIGMSGRFPQADSVHELWDNLKNGKSCISDIPGERRDWGRANRDPEKAV PRWGAFLKDIDRFDPLFFQISPKEAESMDPRQRIFLEEAWHTFEDAGYMGDRIKGKSC GVYVGVEEGEYAHLTGDTDYINGTQNATLSARIAYALDLKGPNMALTAACSSGLVAIH QACSALRQGDCEMALAGGVSLNISHMSFEALTRAEMLSPNGQCKVFDQDANGLVPGEA VAAVLLKPLSKAIEDKDHIYGCIKASGVNYDGKTNGITAPNPFSQAELIENIYEKNEI NPLDIQYVMAHSTGSNLGDPLEVQALTSVFSKYTKQKQFCMISSIKPLIGHTFAASGT VALISMLMAMKNQIIPATHHCESENPYIPFKESPFVLCKENRSWIKKNQKPRMGTIST TGISGTNAHAVIEEYIPDDQPSTQRHQGSPQIFVISAQNDDRLQDAACRMIAYLEQNH NLSLPDVAYTLQVGRKAMEARLAIVANNQEQLVRKLKEYVEAMKNGGVSGQQRSLYTG YTEGILEEQDEAVLQALAKERNLENIAECWVKGYQIPWELLHDGDDVRMVSLPGYPFA RERYWISSGTQQSEAVKQHSQDMKTEIDEPNGKTHIQKIIVQFLARELGISEDRINFK RNFLDYGMDSILGRKLMRHIEKTTQLKMAGREILECQTVQALSDHLALKAEKQNHSAA AHHIKGTYTDEQIIGLMQEVALGKLDFKSVQNIIEGSKSYES*" gene 1821553..1834341 /gene="pksM" /locus_tag="BSU_17200" /old_locus_tag="BSU17200" CDS 1834409..1850875 /gene="pksN" /locus_tag="BSU_17210" /old_locus_tag="BSU17210" /function="16.8: Protect" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1c: Function from experimental evidences in the studied genus; PubMedId: 16460000, 16707694, 17234808, 22720735, 26284661; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="trans AT polyketide synthase of type I involved in bacillaene synthesis" /protein_id="NP_389602.3" /db_xref="EnsemblGenomes-Gn:BSU17210" /db_xref="EnsemblGenomes-Tr:CAB13604" /db_xref="GOA:O31782" /db_xref="InterPro:IPR000873" /db_xref="InterPro:IPR001242" /db_xref="InterPro:IPR006162" /db_xref="InterPro:IPR009081" /db_xref="InterPro:IPR010071" /db_xref="InterPro:IPR013968" /db_xref="InterPro:IPR014030" /db_xref="InterPro:IPR014031" /db_xref="InterPro:IPR016039" /db_xref="InterPro:IPR018201" /db_xref="InterPro:IPR020806" /db_xref="InterPro:IPR020807" /db_xref="InterPro:IPR020841" /db_xref="InterPro:IPR020845" /db_xref="InterPro:IPR025110" /db_xref="InterPro:IPR032821" /db_xref="InterPro:IPR036291" /db_xref="InterPro:IPR036736" /db_xref="SubtiList:BG12652" /db_xref="UniProtKB/Swiss-Prot:O31782" /translation="MKRQLKSPLSEGQKGLWMLQKMSPGMSAYNIPLCFRFSKPIHAE TFKKALLFVQRQYPVLASVIQEENGIPFQSVQLSKDLYFVEEDISAMKSADIMPFLKE KAKEPFQLEAGPLWRTHLFHRLEECIVLITIHHIIFDGVSMLTLISALFEAYQQLLNG IEPLQQPSTADYYDFVDWENRMLTGREGEEHLAYWKEQLSGSLPVLDLPADRPRSSAR KFKGQAYKSLLPHHLRNQIKSFARTNHVNESVVFLSIYKVLLHHYTKQKDIIVGVPTM GRQEDRFETLIGYFINMMAVRSKNIGSQPLTAFIRELQLTVAVGLDHAAFPFPALVRE LNVDRSAADSPVFQTAFLYQNFFQATGLQKVLEPYQTLGIEYIEDIRQEGEFELALEI YEQENETVLHLLYNPDLYELSSIESMMENYMKLAQHMMEDPSLPLEAYSLQLNQEQTS LLEQWNATGTNIANDKCIHEVFEEKAKQTPDAVAVMFEDRSLTYKEVDEKSTSVAVYL QHQGVRPEQPVGICAERSFDMIIGILGILKAGGAYVPLDPSFPQERLKYMLKDSQASI VLTQPNVHDRISGLTGSHVKAINIELACRNGYTDQQSSGLKREVKPEHLAYIIYTSGS TGEPKGVMVEHRSIMNTLNFLESHYPVTAEDAYLLKTNYVFDVSISELFGWFIGDGRL VILPPNGEKSPQLCMDYIETYKVTHINFVPAMLHVFLEMAKDNKRFTEDGPLKYMMVA GEAFPKVLVKKAVSLFTNCRVENIYGPTEASIYAAYFGCGKGDIASHHTPIGKPVSNT KIYIVDQHLKPVPIGKPGELCIAGAGLARGYFKKPGLTAEKFIDNPFESGTKLYKSGD SARWLPDGNIEYLGRIDSQVKIRGFRVELGAIETKLGEFPGILDQAVVVKQLEGHQQL AAYYTEESGHASANPKDLRLHLKSSLPEYMIPSHFIRLDELPLSPSGKVNRKELEKRE IVFNRRKPNHLQLTEIEDQVLRIWEETLKVSGFGPEDGFFDAGGDSLLAVAVAERIKK EFDCEFHVTELFEYSTIRAISEYILEMKNSDLAGTQNEDDHDDKKDGKYPKQKIPPYF DDSVAIVGISCQFPGAKNHHDFWNHIKEGKESIRFFSEEELRANGVPEELIQHPDYVP VQSVIEGKDLFDPGFFQISPKDAEYMDPQLRLLLLHSWKAIEDAGYVAKEIPATSVYM SASSNSYRTLLPKETTEGHESPDGYVSWVLAQSGTIPTMISHKLGLKGPSYFVHSNCS SSLVGLYQAYKSLTSGESQYALVGGATLHAQSAIGYVHQNGLNFSSDGHVKAFDASAD GMAGGEGVAVILLKKAVDAVKDGDHIYAIMRGIGINNDGAEKAGFYAPSVKGQTEVIQ HVLDTTKIHPETVSYIEAHGTGTKLGDPIEMSALNKVYKQYTDKTQFCGIGSVKTNIG HLDTAAGLAGCIKVAMSLYHNELAPTINCTEPNPDIKFESSPFYVVRERKSLEKHAGV HRAALSSFGLGGTNAHAIFEQYENISDAGAENEGNQPYIIPISAKNSERLQVYAKEML SYISQDEQRHFSLRDIAYTFQVGREAMDNRIVFIVNDLEEWKHQLEAFVTGKPLAEGC IQGEKTRMTSAEQLLGNAEADDMASSRISKEELRKLAEMWANGFHVEWRRLYPNIKPR RISLPTYPFAEERYWPESSTGAITTIEPSRLHPLVHHNTSVLSEQRFSSIFTGQEYFI AEHIIKGMAILPAAVTLEMARAAIEQGIGGLEDHETGIRLKNVVWVRPVVAGSEPVQV NIGLYDEDGGHIAYRMYGDPESADAEPVVYNQGKAELIQLKREKALDLSKIKKQCDQS KMDAASFYEGMIGADYGPGYKSVEAVYKGDGQLLAKLSLPESVAHTLGDYVLHPSVMD GALQAAEYLQNVVRAELSDTEDFKAALPFALEELEVFRQCVSDMWVYVQFNSKNKPGD LIQKVDIHLCDEHGMICVRLKGFSTRVMEADIQTEPSKINAETLLLQPVWQEQKAANS LAAKKYAEHLVFLCEYDHETRKQIEAAIEDVHVYSLEARPSSVDGRFHSYTEQVFKKV QEIIRTKPKDGILVQIVTSAEGEQQLFSGLTGLLKTACQENAKLTGQMIEVSSEESGE SIAGKLLENQMSSDSYVKYQNGTRYIADWREIKQAKGDGSKPWKDNGVYLISGGAGGL GHIFAKEIAEQTKNATVILAGRSPLSESKSKKLKELHSKGADITYRQTDVTNKIEVYQ LIDDIQKRYGRLNGILHSAGIIKDSYLVNKQAKDLHDVLAPKVKGLVYLDEASKDLPL DFFILFSSLSGSLGSIGQSDYAAANVFMDMYAGYRNRLADLSQRHGQTLSVNWPLWRD GGMQVDQETEKRLVQLAGIVPMRAEKGIQALYQALHSEANQVMVIEGDVQKIKQNMLA KNASAPMEKKEAEHMTEQINSIDADSLLDKVKAMLKREIAKLLKVKLETIDDHAEMTV YGFDSISMTEFTNHINRAYQLELTPTVFFDHPTIHAFGKHLSEEYQSVFAKTFAVRAV SAQLQPAAKQEQAVRAKAKRRRKQQVMLPNAIQSDAGPEPIAIVGISGIFPMAKDVEA YWNILKEGKDCMTEIPKDRWDWREYEGDPAKEVNKTNVKWGGFIDGIADFDPLFFGIS PREAEQMEPQQRLLLTYAWKAIEDAGYSAKRLSGTKTGVFIGTGNTGYSSLLSKANSA IEGSAAANTSPSVGPNRVSYFLNLHGPSEPVDTACSSSLVAIHHAISSIEEGTCDMAL AGGVNTIILPEVYISFDKAGALSKEGKCKTFSNQADGFAHGEGAGILFLKKLKAAEEA GDHIYGVIKGSAINHGGRAASLTTPNPKAQADVIQSAYQKAGIDPKTVTYIEAHGTGT ELGDPVEINGLKSAFKALGVNEGDTSANPYCGLGSVKTNIGHLSLAAGAAGVIKILLQ LKHKTLVKSLHCENVNPYIQLKNSPFYIVRETEEWKALKNEQGEELPRRAGVSSFGIG GVNAHVIIEEYIPEASDENIPSIAPEHPGIFVLSAKNEARLKEHAQQLADALDKQTYS DVNLARIAYTLQAGRDAMEERLGIISGSIEDLQKKLKDFAAEKSGVEDVFKGRIDKGT LQMLTEDEEIQEAVEKWMERGKYAKLLELWVKGLDVDWTKLYGENLPKRISLPTYPFA KDRYWISDHIEKSGSIDANQAASRLGGAVLHPLMHQNTSNLSEQRFSSIYTGEEFFLA DHVVKGQRILPGVAHLELARAAVEQAAEVQGVPRIMKLKNAVWVRPIVVEDQPQQVHI RLLPGENGEISYEIYGHSDVTGEQSIVYSQGSAVLNPAENLPAVDLQSLREQCQESHF SVNEVYDTYRMIGFEYGPAYRGVKKIYTAEQFVLAKLSLHPSAADTLSQYKMHPGLMD SALQASSILTGAGDNQLTLPFAVQELEVFGACSSEMWVYARYSQGSKATDKVQKRDMD ILDESGNVCVRMKGLSFRAAEGGSGSAESDQTLATLMFEEKWVPKDFKKESPEPHYER HIVMLCDMNGLSKDRIESRMTGAECIVLESFREGLAERFQDYAEQALETVQGLLKSRP QGNVLIQLLTSAQRKQYSFSGLSALLKTAGLENKKLIGQTIEIDSHENVESVIEKLKE NKRHTEDQHIKYEKGKRYINDLDEMQIDDREISMPWRDKGVYLITGGAGGLGFIFAKE IARQAEQPVLILTGRSALNADQQAELNELQQLGARAEYRQVDVTQTEAASELITSITS DYEDLNGVIHSAGLIKDNYLMSKTNEELTQVLAPKVKGLVNVDEATEHLALDFFILFS SISSVAGSAGQADYAMANAFMDSYAAYRNALVTAMYRHGQTLSINWPLWKEGGMRANK EIENMTLKNTGVTPMRTETGIQALYKGLAFGKDQVIVMEGFKDMMREKLTQKPSSDDV PMKTVQVRVTSEARMDQGNMFDHIQEVLKQTISQLLKIKPEEIDPDMEFNQYGFDSIT LTEFANTLNEKCKLDLTPTVFFEHATVYAFAGYLSEEYPNAFTAQTPAKAEVLMQPVE QNIKNMTFSTENRFVKPSVTPMQKEADHKPEPIAIVGMSGVFPKAKDVEEYWKNLSSG ADCITEVPKDRWDWQEYYGDPLKEANKTNVKWGGFIDEVADFDPLFFGISPLEAEQME PQQRLLMTYAWKAVEEAGHSARSLAGTKTGIFIGTGNTGYSSLLSNVDIEGSAAANMS PSAGPNRVSYFLNIHGPSEPIDTACSSSLVAIHHAVCAIENGNCEMAIAGGVNTVVTP QGHIAYDKAGALSKEGRCKTFSDKADGFAVSEGAGILFLKKLTAAERDGDHIYGVIKG SAVNHGGRANSLTTPNPKAQADVVKTAYEKAGIDPRTVTYIEAHGTGTELGDPVEING LKAAFKELYEKTGDPAVHGSHCGLGSAKTNIGHLSLAAGVAGVIKVLLQLKHKTLVKS LYSETVNPYIRLDDSPFYIVQESREWQALRDEAGRELPRRAGISSFGIGGVNAHVVIE EYIPKETTHPATAPAVTAQHPGIFILSAKDEDRLKDQARQLADFISKRSITARDLTDI AYTLQEGRDAMEERLGIIAVSTGDLLEKLNLFIEGGTNAKYMYRGRAEKGIAQTLRSD DEVQKTLNNSWEPHIYERLLDLWVKGMEIGWSKLYDGKQPKRISLPTYPFAKERYWIT DTKEEAAAHQTALKTVESAALHPLIHVNTSDLSEQRFSSAFTGAEFFFADHKVKGKPV MPGVAYLEMVHAAVTRAVRRTEDQQSVIHIKNVVWVQPIVADGQPVQVDISLNPQQDG EIAFNVYTEAAHNDRKIHCQGSASIRGAGDIPVQDISALQDQCSLSTLSHDQCYELFK AIGIDYGPGFQGIDRLYIGRNQALAELSLPAGVTHTLNEFVLHPSMADSALQASIGLK LNSGDEQLSLPFALQELEIFSPCTNKMWVSVTSRPNEDKIQRLDIDLCDEQGRVCVRI KGITSRLLEEGIQPPDGPTSLGNSKATLNGALLMAPIWDRVQLEKRSISPADERVVIL GGDDNSRKAVQREFPFAKELYIEPNASIHRITGQLEALGSFDHIVWMSPSRVTECEVG DEMIEAQDQGVIQMYRLIKAMLSLGYGQKEISWTIVTVNTQYVDQHDIVDPVDAGVHG LIGSMSKEYPNWQTKLIDVKKYEDLPLSQLLSLPADQEGNTWAYRNKIWHKLRLIPVH NNQPVHTKYKHGGVYVVIGGAGGIGEAWSEYMIRTYQAQIVWIGRRKKDAAIQSKLDR FARLGRAPYYIQADAANREELERAYETMKQTHREINGIIHSAIVLQDRSLMNMSEECF RNVLAAKVDVSVRMAQVFRHEPLDFVLFFSSVQSFARASGQSNYAAGCSFKDAFAQRL SQVWPCTVAVMNWSYWGSIGVVSSPDYQKRMAQAGIGSIEAPEAMEALELLLGGPLKQ LVMMKMANETNDEAEQTEETIEVYPETHGSAIQKLRSYHPGDNTKIQQLL*" gene 1834409..1850875 /gene="pksN" /locus_tag="BSU_17210" /old_locus_tag="BSU17210" CDS 1850890..1858521 /gene="pksR" /locus_tag="BSU_17220" /old_locus_tag="BSU17220" /function="16.5: Explore" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1c: Function from experimental evidences in the studied genus; PubMedId: 10960106, 15480790, 16707694, 17234808, 22720735, 26284661; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="trans AT polyketide synthase involved in nonribosomal synthesis of bacillaene" /protein_id="NP_389604.2" /db_xref="EnsemblGenomes-Gn:BSU17220" /db_xref="EnsemblGenomes-Tr:CAB13606" /db_xref="GOA:O31784" /db_xref="InterPro:IPR001031" /db_xref="InterPro:IPR006162" /db_xref="InterPro:IPR009081" /db_xref="InterPro:IPR013217" /db_xref="InterPro:IPR014030" /db_xref="InterPro:IPR014031" /db_xref="InterPro:IPR016039" /db_xref="InterPro:IPR018201" /db_xref="InterPro:IPR020615" /db_xref="InterPro:IPR020806" /db_xref="InterPro:IPR020807" /db_xref="InterPro:IPR020841" /db_xref="InterPro:IPR029058" /db_xref="InterPro:IPR029063" /db_xref="InterPro:IPR032821" /db_xref="InterPro:IPR036736" /db_xref="PDB:4U3V" /db_xref="SubtiList:BG12654" /db_xref="UniProtKB/Swiss-Prot:O31784" /translation="MLNTEDILCKMLFAQLQSIGFFTESKSQPVLENFYGRWFEESQS ILERHQFLKRTENGHVPTRSIGTMSELWKEWNEQKFDLLQDNNMKAMVTLVETALKAL PEILTGKASATDILFPNSSMDLVEGVYKNNQVADYFNDVLADTLTAYLQERLKQEPEA KIRILEIGAGTGGTSAAVFQKLKAWQTHIKEYCYTDLSKAFLMHAENKYGPDNPYLTY KRFNVEEPASEQHIDAGGYDAVIAANVLHATKNIRQTLRNAKAVLKKNGLLLLNEISN HNIYSHLTFGLLEGWWLYEDPDLRIPGCPGLYPDTWKMVLESEGFRYVSFMAEQSHQL GQQIIAAESNGVVRQKKRTEAEEDPSHIQMNAEIDHSQESDSLIEQTAQFVKHTLAKS IKLSPERIHEDTTFEKYGIDSILQVNFIRELEKVTGELPKTILFEHNNTKELVEYLVK GHENKLRTALLKEKTKPAKNEAPLQTERTDPNKPFTFHTRRFVTEQEVTETQLANTEP LKIEKTSNLQGTHFNDSSTEDIAIIGVSGRYPMSNSLEELWGHLIAGDNCITEAPESR WRTSLLKTLSKDPKKPANKKRYGGFLQDIEAFDHQLFEVEQNRVMEMTPELRLCLETV WETFEDGGYTRTRLDKLRDDDGVGVFIGNMYNQYFWNIPSLEQAVLSSNGGDWHIANR VSHFFNLTGPSIAVSSACSSSLNAIHLACESLKLKNCSMAIAGGVNLTLDLSKYDSLE RANLLGSGNQSKSFGTGNGLIPGEGVGAVLLKPLSKAMEDQDHIYAVIKSSFANHSGG RQMYTAPDPKQQAKLIVKSIQQSGIDPETIGYIESAANGSALGDPIEVIALTNAFQQY TNKKQFCAIGSVKSNLGHLEAASGISQLTKVLLQMKKGTLVPTINAMPVNPNIKLEHT AFYLQEQTEPWHRLNDPETGKQLPRRSMINSFGAGGAYANLIIEEYMETAPEKEHIAP RQQEFTAVFSAKTKWSLLSYLENMQLFLEKEASLDIEPVVQALHRRNHNLEHRTAFTV ASTQELIEKLKVFRTSRESSLQQGIYTSFDLQPCAESASRDREINAAEQWAQGALIAF KEADIGNRTGWVHLPHYAFDHNTSFHFDVSSINEKSSDVEDNINQPVIQDQFTYDEPY VQGHVFNNERVLVGATYGSLAIEAFFNLFPEENSGRISKLSYISPIVIKQGETIELQA KPLQKDQVIELQIMYREPSSGLWKPAAIGQCGIGSFEPKKVNIENVKHSLTKLHHIDQ MYKTGNGPEWGELFKTITHLYRDHKSILAKIRLPQSGLANGHHYTVSPLMTNSAYLAI LSFLEQFDMTGGFLPFGINDIQFTKQTIKGDCWLLITLVKNTGDMLLFDVDVINESSE TVLHYSGYSLKQLRISNQRGNQNKAIKASNLKARIRSYVTDKLAVNMADPSKLSIAKA HIMDFGIDSSQLVALTREMEAETKIELNPTLFFEYPTIQELIDFFADKHEASFAQLFG EAHQQEERPAQIENQMKQIPAYETNTDKTIEHAADGIAIIGMSGQFPKANSVTEFWDN LVQGKNCVSEVPKERWDWRKYAAADKEGQSSLQWGGFIEGIGEFDPLFFGISPKEAAN MDPQEFLLLIHAWKAMEDAGLTGQVLSSRPTGVFVAAGNTDTAVVPSLIPNRISYALD VKGPSEYYEAACSSALVALHRAIQSIRNGECEQAIVGAVNLLLSPKGFIGFDSMGYLS EKGQAKSFQADANGFVRSEGAGVLIIKPLQKAIEDSDHIYSVIKGSGVSHGGRGMSLH APNPAGMKDAMLKAYQGAQIDPKTVTYIEAHGIASPLADAIEIEALKSGCSQLELELP QEVREEAPCYISSLKPSIGHGELVSGMAALMKVSMAMKHQTIPGISGFSSLNDQVSLK GTRFRVTAENQQWRDLSDDAGKKIPRRASINSYSFGGVNAHVILEEYIPLPKPPVSMS ENGAHIVVLSAKNQDRLKAIAQQQLDYVNKQQELSLQDYAYTLQTGREEMEDRLALVV RSKEELVIGLQACLAEKGDKLKSSVPVFSGNAENGSSDLEALLDGPLREMVIETLLSE NNLEKIAFCWTKGVQIPWEKLYQGKGARRIPLPTYPFEKRSCWNGFQAVENTPSVSQD ERINNSSDHHILANVLGMAPDELQFHKPLQQYGFDSISCIQLLQQLQSKVDPLIVLTE LQACHTVQDMMDLIAKKQEDTSLQNDQARTFPELIPLNDGKRGRPVFWFHGGVGGVEI YQQFAQKSQRPFYGIQARGFMTDSAPLHGIEQMASYYIEIIRSIQPEGPYDVGGYSLG GMIAYEVTRQLQSQGLAVKSMVMIDSPYRSETKENEASMKTSMLQTINTMLASIAKRE KFTDVLISREEVDISLEDEEFLSELIDLAKERGLNKPDKQIRAQAQQMMKTQRAYDLE SYTVKPLPDPETVKCYYFRNKSRSFFGDLDTYFTLSNEKEPFDQAAYWEEWERQIPHF HLVDVDSSNHFMILTEPKASTALLEFCEKLYSNRGVVNANFLKAFRKKHEAREEKETD ELVKR*" gene 1850890..1858521 /gene="pksR" /locus_tag="BSU_17220" /old_locus_tag="BSU17220" downshifts 1858510 /Source="Nicolas_upshifts" /id="D927" /incds=0 /nref=65 /ntot=216 /MaxReadThrough="0.92789" /MaxDrop="5.77685" /score="4.87908333" /energy="-14.6" /TU="NA" /idTUdmin="U1370" /TUdmin=1 /isTUend="TRUE" CDS complement(1858566..1859783) /gene="pksS" /locus_tag="BSU_17230" /old_locus_tag="BSU17230" /function="16.5: Explore" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1c: Function from experimental evidences in the studied genus; PubMedId: 17482575, 16707694, 17234808, 17886826, 26284661; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="cytochrome P450 of bacillaene metabolism" /protein_id="NP_389605.2" /db_xref="EnsemblGenomes-Gn:BSU17230" /db_xref="EnsemblGenomes-Tr:CAB13607" /db_xref="GOA:O31785" /db_xref="InterPro:IPR001128" /db_xref="InterPro:IPR002397" /db_xref="InterPro:IPR017972" /db_xref="InterPro:IPR036396" /db_xref="PDB:4YZR" /db_xref="SubtiList:BG12655" /db_xref="UniProtKB/Swiss-Prot:O31785" /translation="MEKLMFHPHGKEFHHNPFSVLGRFREEEPIHRFELKRFGATYPA WLITRYDDCMAFLKDNRITRDVKNVMNQEQIKMLNVSEDIDFVSDHMLAKDTPDHTRL RSLVHQAFTPRTIENLRGSIEQIAEQLLDEMEKENKADIMKSFASPLPFIVISELMGI PKEDRSQFQIWTNAMVDTSEGNRELTNQALREFKDYIAKLIHDRRIKPKDDLISKLVH AEENGSKLSEKELYSMLFLLVVAGLETTVNLLGSGTLALLQHKKECEKLKQQPEMIAT AVEELLRYTSPVVMMANRWAIEDFTYKGHSIKRGDMIFIGIGSANRDPNFFENPEILN INRSPNRHISFGFGIHFCLGAPLARLEGHIAFKALLKRFPDIELAVAPDDIQWRKNVF LRGLESLPVSLSK*" gene complement(1858566..1859783) /gene="pksS" /locus_tag="BSU_17230" /old_locus_tag="BSU17230" downshifts complement(1858585) /Source="Nicolas_upshifts" /id="D928" /incds=0 /nref=123 /ntot=225 /MaxReadThrough="0.911470000000001" /MaxDrop="4.23567" /score="16.9796453" /energy="-16.8" /TU="NA" /idTUdmin="U1373" /TUdmin=0 /isTUend="TRUE" promotor_no_box complement(1859798..1859898) /Source="Nicolas_upshift_promotors" /id="U1372" /multdbtbs="-" /comp="M21" /sig="Sig-" /pcomp="0.53046953046953" /psig="0.297702297702298" /xcortree=1727 /SigmaFactorBS="ctaagatagatatatagttttagagacaggattacatttcaa atcattctgttttttgtaaactaattcagcaatttgattcatctatttaccctattag g" /listShort="pksS" /GFF_Attribute="listLong" /label="promotor_no_box" upshifts complement(1859838) /Source="Nicolas_upshifts" /id="U1372" /multdbtbs="-" /comp="M21" /sig="Sig-" /pcomp="0.53046953046953" /psig="0.297702297702298" /xcortree=1727 /SigmaFactorBS="ctaagatagatatatagttttagagacaggattacatttcaa atcattctgttttttgtaaactaattcagcaatttgattcatctatttaccctattag g" /listShort="pksS" /GFF_Attribute="listLong" promotor_-10 complement(1859870..1859889) /Source="Nicolas_upshift_promotors" /id="U1373" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.85014985014985" /psig="0.999000999001" /xcortree=3215 /SigmaFactorBS="gccgttttttcacttttttcgttcttctcccTATTGAATgac gcctaagatagATATATAGTTTTAGAGACAGgattacatttcaaatcattctgttttt t" /listShort="pksS" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1859882) /Source="Nicolas_upshifts" /id="U1373" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.85014985014985" /psig="0.999000999001" /xcortree=3215 /SigmaFactorBS="gccgttttttcacttttttcgttcttctcccTATTGAATgac gcctaagatagATATATAGTTTTAGAGACAGgattacatttcaaatcattctgttttt t" /listShort="pksS" /GFF_Attribute="listLong" S_feature complement(1859884..1859964) /Source="Nicolas_S_feature" /locus_tag="new_1859884_1859964_c" /HighExp="Salt, Etha, T-3.40H, T-0.40H, T-1.40H, LoTm, T-2.40H, S1, SMM, T-4.40H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="Sig-" /TUshortPSig="0.122" /TUlongSig="NA" /TUlongPSig="NA" /label="S618" promotor_-35 complement(1859904..1859911) /Source="Nicolas_upshift_promotors" /id="U1373" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.85014985014985" /psig="0.999000999001" /xcortree=3215 /SigmaFactorBS="gccgttttttcacttttttcgttcttctcccTATTGAATgac gcctaagatagATATATAGTTTTAGAGACAGgattacatttcaaatcattctgttttt t" /listShort="pksS" /GFF_Attribute="listLong" /label="promotor_-35" downshifts complement(1860008) /Source="Nicolas_upshifts" /id="D929" /incds=0 /nref=24 /ntot=184 /MaxReadThrough="3.69744" /MaxDrop="5.18486" /score="-0.71313204" /energy="-20.1" /TU="U1374" /idTUdmin="U1375" /TUdmin=28 /isTUend="FALSE" CDS complement(1860014..1860370) /gene="ymzB" /locus_tag="BSU_17240" /old_locus_tag="BSU17240" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 11544224, 15805528, 20817675" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function involved in ethanol resistance" /protein_id="NP_389606.3" /db_xref="EnsemblGenomes-Gn:BSU17240" /db_xref="EnsemblGenomes-Tr:CAB13608" /db_xref="SubtiList:BG13435" /db_xref="UniProtKB/Swiss-Prot:O31786" /translation="MAHTNTQLSQWLESKVGQTLDIRKGELTHDEEISDLDQIVLHLQ KVAIRSTNHPDDYVAKEELVLEGEGTTFTEDGNVPLPQNAYEIPLLGELHIHQENEGL KVVTDRAVYTIDIQHS*" gene complement(1860014..1860370) /gene="ymzB" /locus_tag="BSU_17240" /old_locus_tag="BSU17240" misc_feature complement(1860430..1860443) /Source="Nicolas_upshift_promotors" /id="U1374" /multdbtbs="-" /comp="M20" /sig="Sig-" /pcomp="0.511488511488511" /psig="0.121878121878122" /xcortree=731 /SigmaFactorBS="ccgtacgctatatcaaggcactcaacagcgaactgtttcata cataaagagtGGGGCGGCTCTTTCccgtgtaaaagatgcagcaattgggaatagtatc g" /listShort="ymzB, S618, pksS" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(1860435) /Source="Nicolas_upshifts" /id="U1374" /multdbtbs="-" /comp="M20" /sig="Sig-" /pcomp="0.511488511488511" /psig="0.121878121878122" /xcortree=731 /SigmaFactorBS="ccgtacgctatatcaaggcactcaacagcgaactgtttcata cataaagagtGGGGCGGCTCTTTCccgtgtaaaagatgcagcaattgggaatagtatc g" /listShort="ymzB, S618, pksS" /GFF_Attribute="listLong" CDS complement(1860449..1861273) /gene="ymaE" /locus_tag="BSU_17250" /old_locus_tag="BSU17250" /function="16.6: Maintain" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 20817675; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative hydrolase" /protein_id="NP_389607.2" /db_xref="EnsemblGenomes-Gn:BSU17250" /db_xref="EnsemblGenomes-Tr:CAB13609" /db_xref="InterPro:IPR001279" /db_xref="InterPro:IPR036866" /db_xref="SubtiList:BG13413" /db_xref="UniProtKB/Swiss-Prot:O31787" /translation="MPYYICNTCGVQHAQTVDPPNSCLICEDERQYIHPDGQTWTTLE DMREKGNLQNILKKEEEHLYSIKTEPEFAIGQTAHLIQHKGFNVLWDCMTYLDQKTID QINELGGIQAIALSHPHYYSTQVEWAEAFQAPIYIHEDDKEWVTRPSNHIHFWSGETL NMKPGLDLYRLGGHFKGGAVLHWSKGNEGKGCLLTGDIITVAADRNWVSFMYSYPNLI PLPASKVEEIAAKVKPLQFNRLYNAFSKVVKENADESVQRSAVRYIKALNSELFHT*" gene complement(1860449..1861273) /gene="ymaE" /locus_tag="BSU_17250" /old_locus_tag="BSU17250" promotor_-10 complement(1861295..1861314) /Source="Nicolas_upshift_promotors" /id="U1375" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.88011988011988" /psig="0.992007992007992" /xcortree=2946 /SigmaFactorBS="gccggcaattctctctcagcagaactgccggttttttcgTTT GAATattcataatcaTAAGGTAAAATAATGGAAAAtagatgaaggaagtgaagaaagt g" /listShort="ymaE, ymzB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1861311) /Source="Nicolas_upshifts" /id="U1375" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.88011988011988" /psig="0.992007992007992" /xcortree=2946 /SigmaFactorBS="gccggcaattctctctcagcagaactgccggttttttcgTTT GAATattcataatcaTAAGGTAAAATAATGGAAAAtagatgaaggaagtgaagaaagt g" /listShort="ymaE, ymzB" /GFF_Attribute="listLong" promotor_-35 complement(1861326..1861332) /Source="Nicolas_upshift_promotors" /id="U1375" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.88011988011988" /psig="0.992007992007992" /xcortree=2946 /SigmaFactorBS="gccggcaattctctctcagcagaactgccggttttttcgTTT GAATattcataatcaTAAGGTAAAATAATGGAAAAtagatgaaggaagtgaagaaagt g" /listShort="ymaE, ymzB" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(1861384..1862712) /gene="aprX" /locus_tag="BSU_17260" /old_locus_tag="BSU17260" /function="16.6: Maintain" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:10589719, 16267290, 17884659, 28693413" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10589719, 16267290, 17884659, 28693413; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="alkaline serine protease" /protein_id="NP_389608.1" /db_xref="EnsemblGenomes-Gn:BSU17260" /db_xref="EnsemblGenomes-Tr:CAB13610" /db_xref="GOA:O31788" /db_xref="InterPro:IPR000209" /db_xref="InterPro:IPR015500" /db_xref="InterPro:IPR022398" /db_xref="InterPro:IPR023827" /db_xref="InterPro:IPR023828" /db_xref="InterPro:IPR036852" /db_xref="SubtiList:BG12567" /db_xref="UniProtKB/Swiss-Prot:O31788" /translation="MFGYSMVQMVRANAHKLDWPLRETVLQLYKPFKWTPCFLHKFFE TKLQNRKKMSVIIEFEEGCHETGFQMAGEVLQKEKRSKLKSRFNKINCCSAEVTPSAL HSLLSECSNIRKVYLNREVKALLDTATEASHAKEVVRNGQTLTGKGVTVAVVDTGIYP HPDLEGRIIGFADMVNQKTEPYDDNGHGTHCAGDVASSGASSSGQYRGPAPEANLIGV KVLNKQGSGTLADIIEGVEWCIQYNEDNPDEPIDIMSMSLGGDALRYDHEQEDPLVRA VEEAWSAGIVVCVAAGNSGPDSQTIASPGVSEKVITVGALDDNNTASSDDDTVASFSS RGPTVYGKEKPDILAPGVNIISLRSPNSYIDKLQKSSRVGSQYFTMSGTSMATPICAG IAALILQQNPDLTPDEVKELLKNGTDKWKDEDPNIYGAGAVNAENSVPGQ*" gene complement(1861384..1862712) /gene="aprX" /locus_tag="BSU_17260" /old_locus_tag="BSU17260" downshifts complement(1861391) /Source="Nicolas_upshifts" /id="D930" /incds=0 /nref=13 /ntot=21 /MaxReadThrough="2.43809" /MaxDrop="5.8915" /score="10.5332562" /energy="-13" /TU="NA" /idTUdmin="U1376" /TUdmin=8 /isTUend="TRUE" promotor_-10 complement(1862735..1862754) /Source="Nicolas_upshift_promotors" /id="U1376" /multdbtbs="SigA" /comp="M5" /sig="SigK" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1433 /SigmaFactorBS="aaaacaaactcttgtctgtctcttacagaggacaaacaAACT TACCAaacctatcatctgTTCATAGAGTATACAGAGAAccttataataggaggaaaat a" /listShort="aprX" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1862754) /Source="Nicolas_upshifts" /id="U1376" /multdbtbs="SigA" /comp="M5" /sig="SigK" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1433 /SigmaFactorBS="aaaacaaactcttgtctgtctcttacagaggacaaacaAACT TACCAaacctatcatctgTTCATAGAGTATACAGAGAAccttataataggaggaaaat a" /listShort="aprX" /GFF_Attribute="listLong" promotor_-35 complement(1862768..1862776) /Source="Nicolas_upshift_promotors" /id="U1376" /multdbtbs="SigA" /comp="M5" /sig="SigK" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1433 /SigmaFactorBS="aaaacaaactcttgtctgtctcttacagaggacaaacaAACT TACCAaacctatcatctgTTCATAGAGTATACAGAGAAccttataataggaggaaaat a" /listShort="aprX" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1862869..1862876 /Source="Nicolas_upshift_promotors" /id="U1378" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.806193806193806" /psig="0.999000999001" /xcortree=1507 /SigmaFactorBS="gatagattcagaagctgaggaaatcattgggGATTGAAAaag aacgtttgttcgTATTATAATGTGATCATATCaaactgggaaggggagagcaaccgta t" /listShort="ymzE, ymzE, S619, ymaC, ymaD" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(1862884..1862903) /Source="Nicolas_upshift_promotors" /id="U1377" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.753246753246753" /psig="0.999000999001" /xcortree=1500 /SigmaFactorBS="ggtgcaagtagaaattcatacggttgctctccCCTTCCCAgt ttgatatgatCACATTATAATACGAACAAAcgttctttttcaatccccaatgatttcc t" /listShort="aprX" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-10 1862892..1862911 /Source="Nicolas_upshift_promotors" /id="U1378" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.806193806193806" /psig="0.999000999001" /xcortree=1507 /SigmaFactorBS="gatagattcagaagctgaggaaatcattgggGATTGAAAaag aacgtttgttcgTATTATAATGTGATCATATCaaactgggaaggggagagcaaccgta t" /listShort="ymzE, ymzE, S619, ymaC, ymaD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1862895) /Source="Nicolas_upshifts" /id="U1377" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.753246753246753" /psig="0.999000999001" /xcortree=1500 /SigmaFactorBS="ggtgcaagtagaaattcatacggttgctctccCCTTCCCAgt ttgatatgatCACATTATAATACGAACAAAcgttctttttcaatccccaatgatttcc t" /listShort="aprX" /GFF_Attribute="listLong" upshifts 1862898 /Source="Nicolas_upshifts" /id="U1378" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.806193806193806" /psig="0.999000999001" /xcortree=1507 /SigmaFactorBS="gatagattcagaagctgaggaaatcattgggGATTGAAAaag aacgtttgttcgTATTATAATGTGATCATATCaaactgggaaggggagagcaaccgta t" /listShort="ymzE, ymzE, S619, ymaC, ymaD" /GFF_Attribute="listLong" promotor_-35 complement(1862916..1862923) /Source="Nicolas_upshift_promotors" /id="U1377" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.753246753246753" /psig="0.999000999001" /xcortree=1500 /SigmaFactorBS="ggtgcaagtagaaattcatacggttgctctccCCTTCCCAgt ttgatatgatCACATTATAATACGAACAAAcgttctttttcaatccccaatgatttcc t" /listShort="aprX" /GFF_Attribute="listLong" /label="promotor_-35" CDS 1862937..1863014 /gene="ymzEn" /locus_tag="BSU_17266" /old_locus_tag="BSU17266" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /pseudo /codon_start=1 /transl_table=11 /product="conserved hypothetical protein; N-terminal part of YmzE" /translation="MNFYLHRSLESQMPISIIYEERRND*" gene 1862937..1863014 /gene="ymzEn" /locus_tag="BSU_17266" /old_locus_tag="BSU17266" /pseudo downshifts complement(1862939) /Source="Nicolas_upshifts" /id="D931" /incds=0 /nref=4 /ntot=7 /MaxReadThrough="1.51659" /MaxDrop="5.37668" /score="10.5332562" /energy="-13" /TU="NA" /idTUdmin="U1377" /TUdmin="-462" /isTUend="FALSE" CDS 1862992..1863168 /gene="ymzEc" /locus_tag="BSU_17267" /old_locus_tag="BSU17267" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /pseudo /codon_start=1 /transl_table=11 /product="conserved hypothetical protein; C-terminal part of YmzE" /db_xref="PSEUDO:CAX52622.1" /translation="MKKDGTISKRTIIVRQKSKTKIKAFCFSKQQIRTFLLDSILSCD FVRTNKQNLYSAGR*" gene 1862992..1863168 /gene="ymzEc" /locus_tag="BSU_17267" /old_locus_tag="BSU17267" /pseudo downshifts 1863149 /Source="Nicolas_upshifts" /id="D932" /incds=0 /nref=42 /ntot=207 /MaxReadThrough="4.03151" /MaxDrop="6.55778" /score="-0.929304655" /energy="-5.5" /TU="U1378" /idTUdmin="U1378" /TUdmin="-1496" /isTUend="FALSE" S_feature 1863194..1863382 /Source="Nicolas_S_feature" /locus_tag="new_1863194_1863382" /HighExp="H2O2, M40t90, C90, M40t45, C30, S8, HiOs, G135, T-4.40H, T-5.40H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S619" misc_feature 1863377..1863396 /Source="Nicolas_upshift_promotors" /id="U1379" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.44955044955045" /psig=1 /xcortree=2371 /SigmaFactorBS="atcaattgattttttgaaaccgggaactttttcactgatgat attgtgtatacAATGGTAAGATAAAACCTATtggctaaacctcatataatgaaccgcg c" /listShort="ymaC, ymaD" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 1863384 /Source="Nicolas_upshifts" /id="U1379" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.44955044955045" /psig=1 /xcortree=2371 /SigmaFactorBS="atcaattgattttttgaaaccgggaactttttcactgatgat attgtgtatacAATGGTAAGATAAAACCTATtggctaaacctcatataatgaaccgcg c" /listShort="ymaC, ymaD" /GFF_Attribute="listLong" CDS 1863448..1864155 /gene="pghC" /locus_tag="BSU_17270" /old_locus_tag="BSU17270" /EC_number="3.4.19.-" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2b: Function from indirect experimental evidences (e.g. phenotypes); PubMedId: 16267290, 26158264; Product type h: extrachromosomal origin" /codon_start=1 /transl_table=11 /product="gamma-polyglutamate hydrolase (phage origin)" /protein_id="NP_389609.1" /db_xref="EnsemblGenomes-Gn:BSU17270" /db_xref="EnsemblGenomes-Tr:CAB13611" /db_xref="GOA:O31789" /db_xref="InterPro:IPR008585" /db_xref="SubtiList:BG13411" /db_xref="UniProtKB/Swiss-Prot:O31789" /translation="MRRFLLNVILVLAIVLFLRYVHYSLEPEPSNQPDTYSNFSSLAE NESPADYDISYNEKKGSKVLIMSPHGGRIEGGVSELVRYFNNEYSTYLFEGLKSHDNQ TLHITSTNFDEPLAKKKIKEHQYVVAFHGYKGENKNTLVGGTDRKRAKMIVRALERRG FSAELASSKSGLAGLNAENINNQGETGLSIQLEISREQREAFFDDFYYKNRKYTKNSE FYAYVSAIKGVLEKEYS*" gene 1863448..1864155 /gene="pghC" /locus_tag="BSU_17270" /old_locus_tag="BSU17270" promotor_-35 1864166..1864172 /Source="Nicolas_upshift_promotors" /id="U1380" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.377622377622378" /psig="0.843156843156843" /xcortree=1826 /SigmaFactorBS="gtgtcctggaaaaagagtattcgtaacaagcagatcAGAAGA CaaaataagagaagATCAGTAGACTGAAATAGGAtaaaaaaggaggcaaaacaatggc a" /listShort="ymaD" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1864186..1864205 /Source="Nicolas_upshift_promotors" /id="U1380" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.377622377622378" /psig="0.843156843156843" /xcortree=1826 /SigmaFactorBS="gtgtcctggaaaaagagtattcgtaacaagcagatcAGAAGA CaaaataagagaagATCAGTAGACTGAAATAGGAtaaaaaaggaggcaaaacaatggc a" /listShort="ymaD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1864190 /Source="Nicolas_upshifts" /id="U1380" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.377622377622378" /psig="0.843156843156843" /xcortree=1826 /SigmaFactorBS="gtgtcctggaaaaagagtattcgtaacaagcagatcAGAAGA CaaaataagagaagATCAGTAGACTGAAATAGGAtaaaaaaggaggcaaaacaatggc a" /listShort="ymaD" /GFF_Attribute="listLong" CDS 1864225..1864677 /gene="ymaD" /locus_tag="BSU_17280" /old_locus_tag="BSU17280" /function="16.8: Protect" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 16267290, 22904090, 25649915; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative peroxiredoxin-related protein" /protein_id="NP_389610.1" /db_xref="EnsemblGenomes-Gn:BSU17280" /db_xref="EnsemblGenomes-Tr:CAB13612" /db_xref="InterPro:IPR003718" /db_xref="InterPro:IPR015946" /db_xref="InterPro:IPR019905" /db_xref="InterPro:IPR036102" /db_xref="SubtiList:BG13412" /db_xref="UniProtKB/Swiss-Prot:O31790" /translation="MADHHFYLKANWPGNRNDVGTIESGNLITSISIPKEMDGPGEGT NPDEMLLGAAATCYIITLAAMMERSGLEKEDLQMESEGIVNVTKGVFTYKKIIHRPSV VLKHDASQDDVALAHKLCKKAESSCMISRAIQGNVELQLEASVKLGGE*" gene 1864225..1864677 /gene="ymaD" /locus_tag="BSU_17280" /old_locus_tag="BSU17280" downshifts 1864665 /Source="Nicolas_upshifts" /id="D933" /incds=0 /nref=44 /ntot=182 /MaxReadThrough="1.35366" /MaxDrop="6.07534" /score="17.0193804" /energy="-12.1" /TU="NA" /idTUdmin="U1379" /TUdmin="-2" /isTUend="TRUE" CDS complement(1864691..1865044) /gene="ebrB" /locus_tag="BSU_17290" /old_locus_tag="BSU17290" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:10735876, 15849754, 16750162, 16850406, 18024586, 22720735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10735876, 15849754, 16750162, 16850406, 18024586, 22720735; Product type t : transporter" /codon_start=1 /transl_table=11 /product="small toxic metabolite efflux transporter subunit" /protein_id="NP_389611.1" /db_xref="EnsemblGenomes-Gn:BSU17290" /db_xref="EnsemblGenomes-Tr:CAB13613" /db_xref="GOA:P0CW82" /db_xref="InterPro:IPR000390" /db_xref="SubtiList:BG12586" /db_xref="UniProtKB/Swiss-Prot:P0CW82" /translation="MRGLLYLALAIVSEVFGSTMLKLSEGFTQAWPIAGVIVGFLSAF TFLSFSLKTIDLSSAYATWSGVGTALTAIVGFLLFGETISLKGVFGLTLVIAGVVVLN QSKAHAEDKKQTACE*" gene complement(1864691..1865044) /gene="ebrB" /locus_tag="BSU_17290" /old_locus_tag="BSU17290" downshifts complement(1864732) /Source="Nicolas_upshifts" /id="D934" /incds=0 /nref=2 /ntot=45 /MaxReadThrough="0.84905" /MaxDrop="2.87924" /score="-2.89884673" /energy="-8.7" /TU="NA" /idTUdmin="U1381" /TUdmin="-11" /isTUend="TRUE" CDS complement(1865058..1865375) /gene="ebrA" /locus_tag="BSU_17300" /old_locus_tag="BSU17300" /function="16.8: Protect" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:10735876, 11104814, 17516673, 18024586" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10735876, 11104814, 17516673, 18024586; Product type t: transporter" /codon_start=1 /transl_table=11 /product="small toxic metabolite efflux transporter subunit" /protein_id="NP_389612.1" /db_xref="EnsemblGenomes-Gn:BSU17300" /db_xref="EnsemblGenomes-Tr:CAB13614" /db_xref="GOA:P0CW80" /db_xref="InterPro:IPR000390" /db_xref="SubtiList:BG12585" /db_xref="UniProtKB/Swiss-Prot:P0CW80" /translation="MLIGYIFLTIAICSESIGAAMLKVSDGFKKWKPSALVVIGYSLA FYMLSLTLNHIPLSLSYATWSGAGTVLTTVIGVKWFKEDLNAKGLIGILLLLSGVVLL NWP*" gene complement(1865058..1865375) /gene="ebrA" /locus_tag="BSU_17300" /old_locus_tag="BSU17300" promotor_-10 complement(1865419..1865438) /Source="Nicolas_upshift_promotors" /id="U1381" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.843156843156843" /psig="0.998001998001998" /xcortree=1863 /SigmaFactorBS="gtctttttaagtgtgtgaaaatgaatcTCTTGACTcatacat aggcataCACTAATATTTTTCTAGCTGaagttttttttctaatctaaaaatatagtga g" /listShort="ebrA, ebrB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1865427) /Source="Nicolas_upshifts" /id="U1381" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.843156843156843" /psig="0.998001998001998" /xcortree=1863 /SigmaFactorBS="gtctttttaagtgtgtgaaaatgaatcTCTTGACTcatacat aggcataCACTAATATTTTTCTAGCTGaagttttttttctaatctaaaaatatagtga g" /listShort="ebrA, ebrB" /GFF_Attribute="listLong" promotor_-35 complement(1865453..1865460) /Source="Nicolas_upshift_promotors" /id="U1381" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.843156843156843" /psig="0.998001998001998" /xcortree=1863 /SigmaFactorBS="gtctttttaagtgtgtgaaaatgaatcTCTTGACTcatacat aggcataCACTAATATTTTTCTAGCTGaagttttttttctaatctaaaaatatagtga g" /listShort="ebrA, ebrB" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(1865512..1865787) /gene="ymaG" /locus_tag="BSU_17310" /old_locus_tag="BSU17310" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:15849754, 16850406, 19775244, 19933362, 22882546" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15849754, 16850406, 19775244, 19933362, 22882546; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="inner spore coat protein; cell wall associated protein" /protein_id="NP_389613.2" /db_xref="EnsemblGenomes-Gn:BSU17310" /db_xref="EnsemblGenomes-Tr:CAB13615" /db_xref="GOA:O31793" /db_xref="SubtiList:BG13415" /db_xref="UniProtKB/Swiss-Prot:O31793" /translation="MNELEHFSPEDTRIFGRPFGFGRPFGFGRPFGFGYGFGRPGFGY GFGRPFGFFGGPFIGGLAGGLIGSALFNPYLYGGYPYYPYAPFPFYY*" gene complement(1865512..1865787) /gene="ymaG" /locus_tag="BSU_17310" /old_locus_tag="BSU17310" downshifts complement(1865513) /Source="Nicolas_upshifts" /id="D935" /incds=0 /nref=38 /ntot=44 /MaxReadThrough="0.28059" /MaxDrop="8.33353" /score="12.3408391" /energy="-11.5" /TU="NA" /idTUdmin="U1383" /TUdmin=0 /isTUend="TRUE" promotor_-35 1865783..1865788 /Source="Nicolas_upshift_promotors" /id="U1382" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.974025974025974" /psig="0.974025974025974" /xcortree=1027 /SigmaFactorBS="gctgaaatgctctaactcgTTCATGttttctttcctcctgTA ATAAAGTGTAGATGATGcagtgtattcaccctgcccggatttgattgggcgaatcgag g" /listShort="ymaF, miaA, ymaH" /listLong="ymzC" /label="promotor_-35" promotor_-10 1865804..1865822 /Source="Nicolas_upshift_promotors" /id="U1382" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.974025974025974" /psig="0.974025974025974" /xcortree=1027 /SigmaFactorBS="gctgaaatgctctaactcgTTCATGttttctttcctcctgTA ATAAAGTGTAGATGATGcagtgtattcaccctgcccggatttgattgggcgaatcgag g" /listShort="ymaF, miaA, ymaH" /listLong="ymzC" /label="promotor_-10" promotor_-10 complement(1865814..1865833) /Source="Nicolas_upshift_promotors" /id="U1383" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1298 /SigmaFactorBS="caatgtgttcacatcctccttttcctcgattcGCCCAATCAA atccgggcagggTGAATACACTGCATCATCTAcactttattacaggaggaaagaaaac a" /listShort="ymaG" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1865824 /Source="Nicolas_upshifts" /id="U1382" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.974025974025974" /psig="0.974025974025974" /xcortree=1027 /SigmaFactorBS="gctgaaatgctctaactcgTTCATGttttctttcctcctgTA ATAAAGTGTAGATGATGcagtgtattcaccctgcccggatttgattgggcgaatcgag g" /listShort="ymaF, miaA, ymaH" /listLong="ymzC" upshifts complement(1865827) /Source="Nicolas_upshifts" /id="U1383" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1298 /SigmaFactorBS="caatgtgttcacatcctccttttcctcgattcGCCCAATCAA atccgggcagggTGAATACACTGCATCATCTAcactttattacaggaggaaagaaaac a" /listShort="ymaG" /GFF_Attribute="listLong" promotor_-35 complement(1865846..1865855) /Source="Nicolas_upshift_promotors" /id="U1383" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1298 /SigmaFactorBS="caatgtgttcacatcctccttttcctcgattcGCCCAATCAA atccgggcagggTGAATACACTGCATCATCTAcactttattacaggaggaaagaaaac a" /listShort="ymaG" /GFF_Attribute="listLong" /label="promotor_-35" CDS 1865876..1866289 /gene="ymaF" /locus_tag="BSU_17320" /old_locus_tag="BSU17320" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 24098137, 25915524" /codon_start=1 /transl_table=11 /product="putative sporulation-related protein of unknown function" /protein_id="NP_389614.2" /db_xref="EnsemblGenomes-Gn:BSU17320" /db_xref="EnsemblGenomes-Tr:CAB13616" /db_xref="InterPro:IPR024307" /db_xref="SubtiList:BG13414" /db_xref="UniProtKB/Swiss-Prot:O31794" /translation="MNTLGLYQSDWSKAPPHAHAYHVKTTREQGHYHLIEGFTQPANG SNTDQHTHYYTGITSFENGHFHRYYGISGPAIPLADGTHYHEIEETTYLAYNEPIEIQ YGGVVYDPGDDRRKTHRHTLKGKTREIVGNEPLGW*" gene 1865876..1866289 /gene="ymaF" /locus_tag="BSU_17320" /old_locus_tag="BSU17320" upshifts 1866340 /Source="Nicolas_upshifts" /id="U1384" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.786213786213786" /psig="0.883116883116883" /xcortree=2366 /SigmaFactorBS="cggctggtagaaggatgtttaccgatgcaaaaaaagggcaaa atggataggtggttgtccatgttgAATGCTATAATGGGGGGAGAtttataaaagagag t" /listShort="miaA, ymaH" /listLong="ymzC, ymzA, S620, S621, nrdI, nrdE, nrdF, ymaB" misc_feature 1866346..1866365 /Source="Nicolas_upshift_promotors" /id="U1384" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.786213786213786" /psig="0.883116883116883" /xcortree=2366 /SigmaFactorBS="cggctggtagaaggatgtttaccgatgcaaaaaaagggcaaa atggataggtggttgtccatgttgAATGCTATAATGGGGGGAGAtttataaaagagag t" /listShort="miaA, ymaH" /listLong="ymzC, ymzA, S620, S621, nrdI, nrdE, nrdF, ymaB" /label="promotor_single_box" /note="Geneious type: promotor_single_box" CDS 1866389..1867333 /gene="miaA" /locus_tag="BSU_17330" /old_locus_tag="BSU17330" /EC_number="2.5.1.75" /function="16.3: Control" /function="16.6: Maintain" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 3045085, 11160115, 26735940, 28277934, 28471404; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="tRNA isopentenylpyrophosphate transferase" /protein_id="NP_389615.2" /db_xref="EnsemblGenomes-Gn:BSU17330" /db_xref="EnsemblGenomes-Tr:CAB13617" /db_xref="GOA:O31795" /db_xref="InterPro:IPR018022" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG12617" /db_xref="UniProtKB/Swiss-Prot:O31795" /translation="MNNTKQPVVILVGPTAVGKTNLSIQLAKSLNAEIISGDSMQIYK GMDIGTAKITEQEMEGVPHHLIDILDPQDSFSTADYQSLVRNKISEIANRGKLPMIVG GTGLYIQSVLYDYTFTEEANDPVFRESMQMAAEREGADFLHAKLAAADPEAAAAIHPN NTRRVIRALEILHTSGKTMSQHLKEQKRELLYNAVLIGLTMDRDTLYERINQRVDLMM QSGLLPEVKRLYDKNVRDCQSIQAIGYKELYAYFDGFVTLSDAVEQLKQNSRRYAKRQ LTWFRNKMQVTWFDMTPPVDMELKKKEIFTHIAGKLEL*" gene 1866389..1867333 /gene="miaA" /locus_tag="BSU_17330" /old_locus_tag="BSU17330" promotor_-35 1867313..1867321 /Source="Nicolas_upshift_promotors" /id="U1385" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=547 /SigmaFactorBS="gatatggagctgaaaaaaaaggaaattttcacacatataGCA GGAAAActcgaactttAATCGAAACTGTATGATATagagaatcaaggaggacgaaaca t" /listShort="ymaH, ymzC, ymzA, S620, S621" /listLong="nrdI, nrdE, nrdF, ymaB" /label="promotor_-35" promotor_-10 1867332..1867350 /Source="Nicolas_upshift_promotors" /id="U1385" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=547 /SigmaFactorBS="gatatggagctgaaaaaaaaggaaattttcacacatataGCA GGAAAActcgaactttAATCGAAACTGTATGATATagagaatcaaggaggacgaaaca t" /listShort="ymaH, ymzC, ymzA, S620, S621" /listLong="nrdI, nrdE, nrdF, ymaB" /label="promotor_-10" upshifts 1867334 /Source="Nicolas_upshifts" /id="U1385" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=547 /SigmaFactorBS="gatatggagctgaaaaaaaaggaaattttcacacatataGCA GGAAAActcgaactttAATCGAAACTGTATGATATagagaatcaaggaggacgaaaca t" /listShort="ymaH, ymzC, ymzA, S620, S621" /listLong="nrdI, nrdE, nrdF, ymaB" CDS 1867373..1867594 /gene="hfq" /locus_tag="BSU_17340" /old_locus_tag="BSU17340" /function="16.3: Control" /function="16.8: Protect" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:16166525, 20445260, 22053080, 23457461, 24932523, 27049793, 27581927" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16166525, 20445260, 22053080, 23457461, 24932523, 27049793, 27581927; Product type f: factor" /codon_start=1 /transl_table=11 /product="Hfq RNA chaperone" /protein_id="NP_389616.1" /db_xref="EnsemblGenomes-Gn:BSU17340" /db_xref="EnsemblGenomes-Tr:CAB13618" /db_xref="GOA:O31796" /db_xref="InterPro:IPR005001" /db_xref="InterPro:IPR010920" /db_xref="PDB:3AHU" /db_xref="PDB:3HSB" /db_xref="SubtiList:BG13416" /db_xref="UniProtKB/Swiss-Prot:O31796" /translation="MKPINIQDQFLNQIRKENTYVTVFLLNGFQLRGQVKGFDNFTVL LESEGKQQLIYKHAISTFAPQKNVQLELE*" gene 1867373..1867594 /gene="hfq" /locus_tag="BSU_17340" /old_locus_tag="BSU17340" downshifts complement(1867384) /Source="Nicolas_upshifts" /id="D936" /incds=0 /nref=3 /ntot=108 /MaxReadThrough="1.19472" /MaxDrop="3.56162" /score="-5.83707008" /energy="-5.2" /TU="NA" /idTUdmin="U1386" /TUdmin=22 /isTUend="TRUE" promotor_-10 complement(1867446..1867450) /Source="Nicolas_upshift_promotors" /id="U1386" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.998001998001998" /psig="0.000999000999001" /xcortree=46 /SigmaFactorBS="ttccaacaatacggtaaagttatcaaagcctttcacctggCC CCGCaactgaaagccgttCAGCAaaaaaacagtgacatacgtattttctttccggatt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1867450) /Source="Nicolas_upshifts" /id="U1386" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.998001998001998" /psig="0.000999000999001" /xcortree=46 /SigmaFactorBS="ttccaacaatacggtaaagttatcaaagcctttcacctggCC CCGCaactgaaagccgttCAGCAaaaaaacagtgacatacgtattttctttccggatt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(1867465..1867470) /Source="Nicolas_upshift_promotors" /id="U1386" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.998001998001998" /psig="0.000999000999001" /xcortree=46 /SigmaFactorBS="ttccaacaatacggtaaagttatcaaagcctttcacctggCC CCGCaactgaaagccgttCAGCAaaaaaacagtgacatacgtattttctttccggatt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 1867594 /Source="Nicolas_upshifts" /id="D937" /incds=0 /nref=26 /ntot=212 /MaxReadThrough="5.10866" /MaxDrop="4.06475" /score="17.2354231" /energy="-17" /TU="U1382,U1385" /idTUdmin="U1384" /TUdmin=0 /isTUend="TRUE" CDS 1867790..1868062 /gene="ymzC" /locus_tag="BSU_17350" /old_locus_tag="BSU17350" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_389617.1" /db_xref="EnsemblGenomes-Gn:BSU17350" /db_xref="EnsemblGenomes-Tr:CAB13619" /db_xref="InterPro:IPR025448" /db_xref="PDB:3KVP" /db_xref="SubtiList:BG13436" /db_xref="UniProtKB/Swiss-Prot:O31797" /translation="MFESEAELRRIRIALVWIAVFLLFGACGNQDTIIETDNGNSDYE TPQPTSFPLEHNHFGVMEDGYIKIYEYNESRNEVKLKKEYADDELE*" gene 1867790..1868062 /gene="ymzC" /locus_tag="BSU_17350" /old_locus_tag="BSU17350" promotor_-35 1868078..1868085 /Source="Nicolas_upshift_promotors" /id="U1387" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.84015984015984" /psig=1 /xcortree=2039 /SigmaFactorBS="cgcggatgatgagcttgaataaaattcacaagcattcGAATT TACaaagcggatgccaGCCGCTAAACTAAATACAGAcacagatcaaacagagggtgaa a" /listShort="ymzA, S620, S621, nrdI, nrdE, nrdF, ymaB, S623" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1868099..1868118 /Source="Nicolas_upshift_promotors" /id="U1387" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.84015984015984" /psig=1 /xcortree=2039 /SigmaFactorBS="cgcggatgatgagcttgaataaaattcacaagcattcGAATT TACaaagcggatgccaGCCGCTAAACTAAATACAGAcacagatcaaacagagggtgaa a" /listShort="ymzA, S620, S621, nrdI, nrdE, nrdF, ymaB, S623" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1868101 /Source="Nicolas_upshifts" /id="U1387" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.84015984015984" /psig=1 /xcortree=2039 /SigmaFactorBS="cgcggatgatgagcttgaataaaattcacaagcattcGAATT TACaaagcggatgccaGCCGCTAAACTAAATACAGAcacagatcaaacagagggtgaa a" /listShort="ymzA, S620, S621, nrdI, nrdE, nrdF, ymaB, S623" /GFF_Attribute="listLong" CDS 1868144..1868374 /gene="ymzA" /locus_tag="BSU_17360" /old_locus_tag="BSU17360" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_389618.1" /db_xref="EnsemblGenomes-Gn:BSU17360" /db_xref="EnsemblGenomes-Tr:CAB13620" /db_xref="SubtiList:BG13434" /db_xref="UniProtKB/Swiss-Prot:O31798" /translation="MKHKVIVNHWEEICEDDSCYEYGTSIIVNGKELIREASIITALK AVLEEIGADVEIEETVESEKCCDSLRKKNLDY*" gene 1868144..1868374 /gene="ymzA" /locus_tag="BSU_17360" /old_locus_tag="BSU17360" S_feature 1868375..1868451 /Source="Nicolas_S_feature" /locus_tag="new_1868375_1868451" /HighExp="dia5, dia15, Diami, B60, G150, H2O2, LPhT, G180, G135, C30" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigH" /TUshortPSig="1, 0.999" /TUlongSig="SigA" /TUlongPSig="0.883" /label="S620" downshifts 1868408 /Source="Nicolas_upshifts" /id="D938" /incds=0 /nref=24 /ntot=61 /MaxReadThrough="7.47169" /MaxDrop="4.19691" /score="8.2587309" /energy="-16.9" /TU="U1385,U1387" /idTUdmin="U1385" /TUdmin="-132" /isTUend="FALSE" S_feature 1868453..1868560 /Source="Nicolas_S_feature" /locus_tag="new_1868453_1868560" /HighExp="G180, G150, G135, H2O2, dia15, Paraq, LBGexp, C30, Diami, Oxctl" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigH" /TUshortPSig="1, 0.999" /TUlongSig="SigA" /TUlongPSig="0.883" /label="S621" promotor_-35 1868533..1868540 /Source="Nicolas_upshift_promotors" /id="U1388" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.653346653346653" /psig=1 /xcortree=3005 /SigmaFactorBS="aatatgaatttttcataaaaacgaatctataTATTGTGTttt tgctagagggTAGTATACTATATATAGTGTtagtgatgagagattcatattttttgat a" /listShort="nrdI, nrdE, nrdF, ymaB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1868554..1868573 /Source="Nicolas_upshift_promotors" /id="U1388" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.653346653346653" /psig=1 /xcortree=3005 /SigmaFactorBS="aatatgaatttttcataaaaacgaatctataTATTGTGTttt tgctagagggTAGTATACTATATATAGTGTtagtgatgagagattcatattttttgat a" /listShort="nrdI, nrdE, nrdF, ymaB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1868562 /Source="Nicolas_upshifts" /id="U1388" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.653346653346653" /psig=1 /xcortree=3005 /SigmaFactorBS="aatatgaatttttcataaaaacgaatctataTATTGTGTttt tgctagagggTAGTATACTATATATAGTGTtagtgatgagagattcatattttttgat a" /listShort="nrdI, nrdE, nrdF, ymaB" /GFF_Attribute="listLong" CDS 1868617..1869009 /gene="nrdI" /locus_tag="BSU_17370" /old_locus_tag="BSU17370" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:12682299, 16885274, 21561096, 22443445, 23402532, 26507228" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12682299, 16885274, 21561096, 22443445, 23402532, 26507228; Product type f : factor" /codon_start=1 /transl_table=11 /product="co-factor of ribonucleotide diphosphate reductase" /protein_id="NP_389619.1" /db_xref="EnsemblGenomes-Gn:BSU17370" /db_xref="EnsemblGenomes-Tr:CAB13621" /db_xref="GOA:P50618" /db_xref="InterPro:IPR004465" /db_xref="InterPro:IPR020852" /db_xref="InterPro:IPR029039" /db_xref="PDB:1RLJ" /db_xref="SubtiList:BG11426" /db_xref="UniProtKB/Swiss-Prot:P50618" /translation="MVQIIFDSKTGNVQRFVNKTGFQQIRKVDEMDHVDTPFVLVTYT TNFGQVPASTQSFLEKYAHLLLGVAASGNKVWGDNFAKSADTISRQYQVPILHKFELS GTSKDVELFTQEVERVVTKSSAKMDPVK*" gene 1868617..1869009 /gene="nrdI" /locus_tag="BSU_17370" /old_locus_tag="BSU17370" CDS 1868969..1871071 /gene="nrdE" /locus_tag="BSU_17380" /old_locus_tag="BSU17380" /EC_number="1.17.4.1" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:12682299, 15937154, 16885274, 17395719, 21561096, 22443445, 23402532, 24401092, 27920297" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12682299, 15937154, 16885274, 17395719, 21561096, 22443445, 23402532, 24401092, 27920297; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="ribonucleoside-diphosphate reductase (major subunit)" /protein_id="NP_389620.1" /db_xref="EnsemblGenomes-Gn:BSU17380" /db_xref="EnsemblGenomes-Tr:CAB13622" /db_xref="GOA:P50620" /db_xref="InterPro:IPR000788" /db_xref="InterPro:IPR008926" /db_xref="InterPro:IPR013346" /db_xref="InterPro:IPR013509" /db_xref="InterPro:IPR013554" /db_xref="InterPro:IPR026459" /db_xref="SubtiList:BG11404" /db_xref="UniProtKB/Swiss-Prot:P50620" /translation="MSQNQVPKWIQLNNEIMIQKDGKFQFDKDKEAVHSYFVDYINQN TVFFHNLKEKLDYLVENQYYEEEFLSLYSFEDIKEVFKTAYAKKFRFPSFMSAFKFYN DYALKTNDKKKILERYEDRISIVALFFANGDTEKAKEYVNLMINQEYQPSTPTFLNAG RKRRGELVSCFLLEVNDSLNDISRAIDISMQLSKLGGGVSLNLSKLRAKGEAIKDVEN ATKGVVGVMKLLDNAFRYADQMGQRQGSGAAYLNIFHRDINDFLDTKKISADEDVRVK TLSIGVVIPDKFVELAREDKAAYVFYPHTIYKEYGQHMDEMDMNEMYDKFVDNPRVKK EKINPRKLLEKLAMLRSESGYPYIMFQDNVNKVHANNHISKVKFSNLCSEVLQASQVS SYTDYDEEDEIGLDISCNLGSLNILNVMEHKSIEKTVKLATDSLTHVSETTDIRNAPA VRRANKAMKSIGLGAMNLHGYLAQNGIAYESPEARDFANTFFMMVNFYSIQRSAEIAK EKGETFDQYEGSTYATGEYFDKYVSTDFSPKYEKIANLFEGMHIPTTEDWKKLKAFVA EHGMYHSYRLCIAPTGSISYVQSSTASVMPIMERIEERTYGNSKTYYPMPGLASNNWF FYKEAYDMDMFKVVDMIATIQQHIDQGISFTLFLKDTMTTRDLNRIDLYAHHRGIKTI YYARTKDTGQDSCLSCVV*" gene 1868969..1871071 /gene="nrdE" /locus_tag="BSU_17380" /old_locus_tag="BSU17380" CDS 1871089..1872078 /gene="nrdF" /locus_tag="BSU_17390" /old_locus_tag="BSU17390" /EC_number="1.17.4.1" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:12682299, 15937154, 16885274, 17395719, 21561096, 22443445, 23402532, 24401092, 27920297" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12682299, 15937154, 16885274, 17395719, 21561096, 22443445, 23402532, 24401092, 27920297; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="ribonucleoside-diphosphate reductase (minor subunit)" /protein_id="NP_389621.1" /db_xref="EnsemblGenomes-Gn:BSU17390" /db_xref="EnsemblGenomes-Tr:CAB13623" /db_xref="GOA:P50621" /db_xref="InterPro:IPR000358" /db_xref="InterPro:IPR009078" /db_xref="InterPro:IPR026494" /db_xref="InterPro:IPR030475" /db_xref="InterPro:IPR033909" /db_xref="PDB:4DR0" /db_xref="SubtiList:BG11405" /db_xref="UniProtKB/Swiss-Prot:P50621" /translation="MTKIYDAANWSKHEDDFTQMFYNQNVKQFWLPEEIALNGDLLTW KYLGKNEQDTYMKVLAGLTLLDTEQGNTGMPIVAEHVDGHQRKAVLNFMAMMENAVHA KSYSNIFMTLAPTETINEVFEWVKQNKYLQKKAQMIVGLYKAIQKDDEISLFKAMVAS VYLESFLFYSGFYYPLYFYGQGKLMQSGEIINLILRDEAIHGVYVGLLAQEIYNKQTE EKKAELREFAIDLLNQLYENELEYTEDLYDQVGLSHDVKKFIRYNANKALMNLGFDPY FEEEDINPIVLNGLNTKTKSHDFFSMKGNGYKKATVEPLKDDDFYFEDEKEQI*" gene 1871089..1872078 /gene="nrdF" /locus_tag="BSU_17390" /old_locus_tag="BSU17390" downshifts 1872038 /Source="Nicolas_upshifts" /id="D939" /incds=0 /nref=3 /ntot=106 /MaxReadThrough="6.49299" /MaxDrop="2.8143" /score="-8.26008921" /energy="-10.8" /TU="U1387,U1388" /idTUdmin="U1388" /TUdmin="-726" /isTUend="FALSE" S_feature complement(1872092..1872751) /Source="Nicolas_S_feature" /locus_tag="new_1872092_1872751_c" /HighExp="BT, B36, C30, Pyr, S8, G135, G/S, Glucon, B60, C90" /AntisenseName="ymaB" /AntisenseCor="-0.136438199650502" /AntisenseRegPval="-1.6" /CDS_PredictionProba="NA" /TUshortSig="SigK" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S622" downshifts complement(1872107) /Source="Nicolas_upshifts" /id="D940" /incds=0 /nref=3 /ntot=8 /MaxReadThrough="2.78803" /MaxDrop="4.0424" /score="6.77419677" /energy="-10.8" /TU="NA" /idTUdmin="U1390" /TUdmin=7 /isTUend="TRUE" CDS 1872128..1872748 /gene="ymaB" /locus_tag="BSU_17400" /old_locus_tag="BSU17400" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 16885274, 21561096; Product type f: factor" /codon_start=1 /transl_table=11 /product="putative cofactor involved in deoxyribonucleotide synthesis" /protein_id="NP_389622.1" /db_xref="EnsemblGenomes-Gn:BSU17400" /db_xref="EnsemblGenomes-Tr:CAB13624" /db_xref="GOA:P50619" /db_xref="InterPro:IPR015797" /db_xref="SubtiList:BG11427" /db_xref="UniProtKB/Swiss-Prot:P50619" /translation="MGKMDEMILVAPRDDVFKKESLTFQGVYSEDSRVAEIMAQIEAA YREMRRGDAEEDPRFKQPIPYVVIKREDEVFLYERLAGGGESRLHNKLSLGFGGHMNA IEGAASFAEVLKLNTDRELEEELQINEEDKQAIVTLGLINDDENSVGKVHIGILSALQ LKPGAQVEVKEKEQIAGKWMKVSELKQDDIYNRLETWSQFVVDILE*" gene 1872128..1872748 /gene="ymaB" /locus_tag="BSU_17400" /old_locus_tag="BSU17400" downshifts 1872729 /Source="Nicolas_upshifts" /id="D941" /incds=0 /nref=130 /ntot=257 /MaxReadThrough="4.3301" /MaxDrop="6.0751" /score="31.3992458" /energy="-16.3" /TU="U1387,U1388" /idTUdmin="U1388" /TUdmin="-35" /isTUend="FALSE" promotor_-35 1872764..1872768 /Source="Nicolas_upshift_promotors" /id="U1389" /multdbtbs="-" /comp="M20" /sig="Sig-" /pcomp="0.631368631368631" /psig="0.230769230769231" /xcortree=1799 /SigmaFactorBS="ttgttgttgatattcttgaataaaaaaacccggtttctCGCG AtgaggagccgggtttttttatGAGACGCTCGTCCCCGTCtcggctatgattctagga t" /listShort="S623" /GFF_Attribute="listLong" /label="promotor_-35" S_feature 1872786..1873153 /Source="Nicolas_S_feature" /locus_tag="new_1872786_1873153" /HighExp="dia15, G180, H2O2, G135, G150, Diami, Paraq, Oxctl, LBGexp, C30" /AntisenseName="cwlC" /AntisenseCor="-8.9131707018362205E-2" /AntisenseRegPval="-0.8" /CDS_PredictionProba="NA" /TUshortSig="Sig-, SigA" /TUshortPSig="0.231, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S623" upshifts 1872786 /Source="Nicolas_upshifts" /id="U1389" /multdbtbs="-" /comp="M20" /sig="Sig-" /pcomp="0.631368631368631" /psig="0.230769230769231" /xcortree=1799 /SigmaFactorBS="ttgttgttgatattcttgaataaaaaaacccggtttctCGCG AtgaggagccgggtttttttatGAGACGCTCGTCCCCGTCtcggctatgattctagga t" /listShort="S623" /GFF_Attribute="listLong" promotor_-10 1872790..1872807 /Source="Nicolas_upshift_promotors" /id="U1389" /multdbtbs="-" /comp="M20" /sig="Sig-" /pcomp="0.631368631368631" /psig="0.230769230769231" /xcortree=1799 /SigmaFactorBS="ttgttgttgatattcttgaataaaaaaacccggtttctCGCG AtgaggagccgggtttttttatGAGACGCTCGTCCCCGTCtcggctatgattctagga t" /listShort="S623" /GFF_Attribute="listLong" /label="promotor_-10" downshifts complement(1872796) /Source="Nicolas_upshifts" /id="D942" /incds=0 /nref=1 /ntot=53 /MaxReadThrough="7.25519" /MaxDrop="4.6417" /score="9.14776993" /energy="-8.9" /TU="U1390" /idTUdmin="U1390" /TUdmin="-682" /isTUend="FALSE" CDS complement(1872812..1873579) /gene="cwlC" /locus_tag="BSU_17410" /old_locus_tag="BSU17410" /EC_number="3.5.1.28" /function="16.5: Explore" /function="16.11: Scavenge (Catabolism)" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:10515909, 10945275, 10974124, 11375403, 16042392" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10515909, 10945275, 10974124, 11375403, 16042392; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="N-acetylmuramoyl-L-alanine amidase (sporulation-specific)" /protein_id="NP_389623.2" /db_xref="EnsemblGenomes-Gn:BSU17410" /db_xref="EnsemblGenomes-Tr:CAB13625" /db_xref="GOA:Q06320" /db_xref="InterPro:IPR002508" /db_xref="InterPro:IPR007730" /db_xref="InterPro:IPR036680" /db_xref="PDB:1X60" /db_xref="SubtiList:BG10825" /db_xref="UniProtKB/Swiss-Prot:Q06320" /translation="MVKIFIDPGHGGSDPGATGNGLQEKTLTLQIALALRTILTNEYE GVSLLLSRTSDQYVSLNDRTNAANNWGADFFLSIHVNSGGGTGFESYIYPDVGAPTTT YQSTIHSEVIQAVDFADRGKKTANFHVLRESAMPALLTENGFIDTVSDANKLKTSSFI QSLARGHANGLEQAFNLKKTSSSGLYKVQIGAFKVKANADSLASNAEAKGFDSIVLLK DGLYKVQIGAFSSKDNADTLAARAKNAGFDAIVILES*" gene complement(1872812..1873579) /gene="cwlC" /locus_tag="BSU_17410" /old_locus_tag="BSU17410" promotor_-10 complement(1873588..1873607) /Source="Nicolas_upshift_promotors" /id="U1390" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1431 /SigmaFactorBS="tgtgaaagggttatttcctcatttttcagttgaatgataatc GTACAAGCAGaagccgtgttttTTCATATCCTGTAATGAGGTgatgaaaaatggttaa a" /listShort="cwlC, S622" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1873611) /Source="Nicolas_upshifts" /id="U1390" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1431 /SigmaFactorBS="tgtgaaagggttatttcctcatttttcagttgaatgataatc GTACAAGCAGaagccgtgttttTTCATATCCTGTAATGAGGTgatgaaaaatggttaa a" /listShort="cwlC, S622" /GFF_Attribute="listLong" promotor_-35 complement(1873620..1873629) /Source="Nicolas_upshift_promotors" /id="U1390" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1431 /SigmaFactorBS="tgtgaaagggttatttcctcatttttcagttgaatgataatc GTACAAGCAGaagccgtgttttTTCATATCCTGTAATGAGGTgatgaaaaatggttaa a" /listShort="cwlC, S622" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1873733..1873738 /Source="Nicolas_upshift_promotors" /id="U1391" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.828171828171828" /psig="0.828171828171828" /xcortree=1459 /SigmaFactorBS="agcgcacaattcaacatgaagcgacaacagatacggtccGAC ATGaaatctgtgcatacgCCATATGTTTGTATGTACTatgggttcggttaacctgcac t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1873754..1873772 /Source="Nicolas_upshift_promotors" /id="U1391" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.828171828171828" /psig="0.828171828171828" /xcortree=1459 /SigmaFactorBS="agcgcacaattcaacatgaagcgacaacagatacggtccGAC ATGaaatctgtgcatacgCCATATGTTTGTATGTACTatgggttcggttaacctgcac t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1873754 /Source="Nicolas_upshifts" /id="U1391" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.828171828171828" /psig="0.828171828171828" /xcortree=1459 /SigmaFactorBS="agcgcacaattcaacatgaagcgacaacagatacggtccGAC ATGaaatctgtgcatacgCCATATGTTTGTATGTACTatgggttcggttaacctgcac t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 1874036..1874041 /Source="Nicolas_upshift_promotors" /id="U1392" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp="0.777222777222777" /psig="0.777222777222777" /xcortree=1148 /SigmaFactorBS="tactctgacaaaatgattaaaaacaaaatctcatGGTTTGtc caccccatgtccgtGAATACAATAAGAAATAAAgtatttctcgggaaagcgcaggatt c" /listShort="S624, spoVK" /listLong="ynbA, ynbB" /label="promotor_-35" promotor_-10 1874058..1874076 /Source="Nicolas_upshift_promotors" /id="U1392" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp="0.777222777222777" /psig="0.777222777222777" /xcortree=1148 /SigmaFactorBS="tactctgacaaaatgattaaaaacaaaatctcatGGTTTGtc caccccatgtccgtGAATACAATAAGAAATAAAgtatttctcgggaaagcgcaggatt c" /listShort="S624, spoVK" /listLong="ynbA, ynbB" /label="promotor_-10" S_feature 1874062..1874202 /Source="Nicolas_S_feature" /locus_tag="new_1874062_1874202" /HighExp="S4, S5, S6, S8, S3, B60, LoTm, S7, T5.0H, B36" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigEF" /TUshortPSig="0.777" /TUlongSig="NA" /TUlongPSig="NA" /label="S624" upshifts 1874062 /Source="Nicolas_upshifts" /id="U1392" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp="0.777222777222777" /psig="0.777222777222777" /xcortree=1148 /SigmaFactorBS="tactctgacaaaatgattaaaaacaaaatctcatGGTTTGtc caccccatgtccgtGAATACAATAAGAAATAAAgtatttctcgggaaagcgcaggatt c" /listShort="S624, spoVK" /listLong="ynbA, ynbB" CDS 1874203..1875171 /gene="spoVK" /locus_tag="BSU_17420" /old_locus_tag="BSU17420" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:8464402, 22882546" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8464402, 22882546; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="mother cell sporulation ATPase" /protein_id="NP_389624.2" /db_xref="EnsemblGenomes-Gn:BSU17420" /db_xref="EnsemblGenomes-Tr:CAB13626" /db_xref="GOA:P27643" /db_xref="InterPro:IPR000641" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR003959" /db_xref="InterPro:IPR014232" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG11039" /db_xref="UniProtKB/Swiss-Prot:P27643" /translation="MLERAVTYKNNGQINIILNGQKQVLTNAEAEAEYQAALQKNEAK HGILKEIEKEMSALVGMEEMKRNIKEIYAWIFVNQKRAEQGLKVGKQALHMMFKGNPG TGKTTVARLIGKLFFEMNVLSKGHLIEAERADLVGEYIGHTAQKTRDLIKKSLGGILF IDEAYSLARGGEKDFGKEAIDTLVKHMEDKQHEFILILAGYSREMDHFLSLNPGLQSR FPISIDFPDYSVTQLMEIAKRMIDEREYQLSQEAEWKLKDYLMTVKSTTSPIKFSNGR FVRNVIEKSIRAQAMRLLMGDQYLKSDLMTIKSQDLSIKEEASGSA*" gene 1874203..1875171 /gene="spoVK" /locus_tag="BSU_17420" /old_locus_tag="BSU17420" downshifts 1875140 /Source="Nicolas_upshifts" /id="D943" /incds=0 /nref=5 /ntot=41 /MaxReadThrough="2.7881" /MaxDrop="5.20495" /score="22.9164064" /energy="-15.5" /TU="U1392" /idTUdmin="U1392" /TUdmin="-109" /isTUend="FALSE" promotor_-35 1875235..1875243 /Source="Nicolas_upshift_promotors" /id="U1393" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.879120879120879" /psig=1 /xcortree=1849 /SigmaFactorBS="ggtctgttttttgctcgtatttccgcttttcaaagcaatcga tttGTGGTATACacatgcagggTTTGGTATGATAATACTACTgcccaatatgcaaaag a" /listShort="ynbA, ynbB, glnR, glnA" /listLong="S625, ynxB, S626, ynzF, ynzG, S627, ynaB, ynaC" /label="promotor_-35" upshifts 1875250 /Source="Nicolas_upshifts" /id="U1393" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.879120879120879" /psig=1 /xcortree=1849 /SigmaFactorBS="ggtctgttttttgctcgtatttccgcttttcaaagcaatcga tttGTGGTATACacatgcagggTTTGGTATGATAATACTACTgcccaatatgcaaaag a" /listShort="ynbA, ynbB, glnR, glnA" /listLong="S625, ynxB, S626, ynzF, ynzG, S627, ynaB, ynaC" promotor_-10 1875254..1875273 /Source="Nicolas_upshift_promotors" /id="U1393" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.879120879120879" /psig=1 /xcortree=1849 /SigmaFactorBS="ggtctgttttttgctcgtatttccgcttttcaaagcaatcga tttGTGGTATACacatgcagggTTTGGTATGATAATACTACTgcccaatatgcaaaag a" /listShort="ynbA, ynbB, glnR, glnA" /listLong="S625, ynxB, S626, ynzF, ynzG, S627, ynaB, ynaC" /label="promotor_-10" CDS 1875304..1876566 /gene="hflX" /locus_tag="BSU_17430" /old_locus_tag="BSU17430" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 19824612, 26458047, 26733579, 26951678, 27398305; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="ribosome-splitting GTPase (also ATPase, rescuingstalled ribosomes, E-site binding)" /protein_id="NP_389625.2" /db_xref="EnsemblGenomes-Gn:BSU17430" /db_xref="EnsemblGenomes-Tr:CAB13627" /db_xref="GOA:P94478" /db_xref="InterPro:IPR006073" /db_xref="InterPro:IPR016496" /db_xref="InterPro:IPR025121" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR030394" /db_xref="InterPro:IPR032305" /db_xref="SubtiList:BG12263" /db_xref="UniProtKB/Swiss-Prot:P94478" /translation="MNEQETIQEKAILVGCQLPHITDEHFENSMEELASLTKTADGKV LTSVTQKRNRADAATYIGKGKVEELKALVEELEADLLIFNDELSPSQLKSLATAIEVK MIDRTQLILDIFAKRARTREGKLQIELAQLQYALPRLTGQGINLSRQGGGIGARGPGE TKLETDRRHIRNRIHEINTQLSTVIRHRSRYRERRKKNGVLQIALVGYTNAGKSTWFN RLTSADSYEEDLLFATLDPMTRKMVLPSGYSVLLSDTVGFIQDLPTTLIAAFRSTLEE VKEADLILHLIDSSNEDYAGHEKTVLRLLEELEADDIPMLTAYNKRDQKLPDFIPTAG RDHIMVSAKFEDDAAAFKEAIQRYLRQELLTSFEAHVPASEGKLLSRIKSETMVDRFY FNEENEQYDISGYVQEEQSIIGELKKYM*" gene 1875304..1876566 /gene="hflX" /locus_tag="BSU_17430" /old_locus_tag="BSU17430" CDS 1876584..1877849 /gene="ynbB" /locus_tag="BSU_17440" /old_locus_tag="BSU17440" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 22333191, 24610841; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative C-S lyase" /protein_id="NP_389626.2" /db_xref="EnsemblGenomes-Gn:BSU17440" /db_xref="EnsemblGenomes-Tr:CAB13628" /db_xref="GOA:P94479" /db_xref="InterPro:IPR000277" /db_xref="InterPro:IPR009651" /db_xref="InterPro:IPR015421" /db_xref="InterPro:IPR015424" /db_xref="SubtiList:BG12264" /db_xref="UniProtKB/Swiss-Prot:P94479" /translation="MFDTLTHGELLKKTAMEVEADIAGIHKQIEEISERNEWRVLQSY RKHKVSDTHFTPSTGYGYDDIGRDTLESIYADVFGGEAGLVRPQIISGTHAISIALFG VLRPGDELLYITGKPYDTLEEIVGVRGGENAGSLKDFQIGYNAVDLTKDGKIDYDAVA AAINPKTKVIGIQRSKGYANRPSFLISEIKEMIRFVKEINENLIVFVDNCYGEFVEEL EPCHVGADLMAGSLIKNPGGGLAKTGGYLVGKAKWIEACSYRMTSPGIGREAGASLYS LQEMYQGFFLAPHVVSQSLKGAVFTARFLEKLGFTSNPKWDAKRTDLIQSVEFSDREK MIAFCQAIQFASPINAHVTPYPAYMPGYEDDVIMAAGTFIQGASIELSADGPIRPPYV AYVQGGLTYSHVKNAICSAVDSLMQKQLI*" gene 1876584..1877849 /gene="ynbB" /locus_tag="BSU_17440" /old_locus_tag="BSU17440" promotor_-35 1877897..1877904 /Source="Nicolas_upshift_promotors" /id="U1394" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.96903096903097" /psig=1 /xcortree=2196 /SigmaFactorBS="atttgatgttaagaatccttacatcgTATTGACAcataatat aacatcACCTATAATGAAACTAAGTTaagaaaaggaggaaattgagatgagtgataat a" /listShort="glnR, glnA, S625, ynxB, S626, ynzF, ynzG" /listLong="S627, ynaB, ynaC" /label="promotor_-35" promotor_-10 1877919..1877938 /Source="Nicolas_upshift_promotors" /id="U1394" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.96903096903097" /psig=1 /xcortree=2196 /SigmaFactorBS="atttgatgttaagaatccttacatcgTATTGACAcataatat aacatcACCTATAATGAAACTAAGTTaagaaaaggaggaaattgagatgagtgataat a" /listShort="glnR, glnA, S625, ynxB, S626, ynzF, ynzG" /listLong="S627, ynaB, ynaC" /label="promotor_-10" upshifts 1877931 /Source="Nicolas_upshifts" /id="U1394" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.96903096903097" /psig=1 /xcortree=2196 /SigmaFactorBS="atttgatgttaagaatccttacatcgTATTGACAcataatat aacatcACCTATAATGAAACTAAGTTaagaaaaggaggaaattgagatgagtgataat a" /listShort="glnR, glnA, S625, ynxB, S626, ynzF, ynzG" /listLong="S627, ynaB, ynaC" CDS 1877959..1878366 /gene="glnR" /locus_tag="BSU_17450" /old_locus_tag="BSU17450" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:9287005, 12374841, 16547045, 16885465, 22625175, 22720735, 25691471" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9287005, 12374841, 16547045, 16885465, 22625175, 22720735, 25691471; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator (nitrogen metabolism)" /protein_id="NP_389627.1" /db_xref="EnsemblGenomes-Gn:BSU17450" /db_xref="EnsemblGenomes-Tr:CAB13629" /db_xref="GOA:P37582" /db_xref="InterPro:IPR000551" /db_xref="InterPro:IPR009061" /db_xref="PDB:4R4E" /db_xref="SubtiList:BG10424" /db_xref="UniProtKB/Swiss-Prot:P37582" /translation="MSDNIRRSMPLFPIGIVMQLTELSARQIRYYEENGLIFPARSEG NRRLFSFHDVDKLLEIKHLIEQGVNMAGIKQILAKAEAEPEQKQNEKTKKPMKHDLSD DELRQLLKNELMQAGRFQRGNTFRQGDMSRFFH*" gene 1877959..1878366 /gene="glnR" /locus_tag="BSU_17450" /old_locus_tag="BSU17450" downshifts complement(1877965) /Source="Nicolas_upshifts" /id="D944" /incds=0 /nref=2 /ntot=82 /MaxReadThrough="1.78139" /MaxDrop="3.45896" /score="-7.83781174" /energy="-10.3" /TU="NA" /idTUdmin="U1398" /TUdmin=3816 /isTUend="FALSE" misc_feature 1878347..1878365 /Source="Nicolas_upshift_promotors" /id="U1395" /multdbtbs="-" /comp="M18" /sig="SigL" /pcomp="0.777222777222777" /psig="0.777222777222777" /xcortree=2197 /SigmaFactorBS="ttttcaaagagggaatacattccgtcaaggcgacaTGTCCCG CTTCTTTCATTAatccgttagcaactgttttgctatatacatttaccttttaagagga g" /listShort="glnA, S625, ynxB, S626" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 1878372 /Source="Nicolas_upshifts" /id="U1395" /multdbtbs="-" /comp="M18" /sig="SigL" /pcomp="0.777222777222777" /psig="0.777222777222777" /xcortree=2197 /SigmaFactorBS="ttttcaaagagggaatacattccgtcaaggcgacaTGTCCCG CTTCTTTCATTAatccgttagcaactgttttgctatatacatttaccttttaagagga g" /listShort="glnA, S625, ynxB, S626" /GFF_Attribute="listLong" downshifts complement(1878425) /Source="Nicolas_upshifts" /id="D945" /incds=0 /nref=1 /ntot=72 /MaxReadThrough="1.70567" /MaxDrop="3.42395" /score="-7.83781174" /energy="-10.3" /TU="NA" /idTUdmin="U1398" /TUdmin=3356 /isTUend="FALSE" CDS 1878425..1879759 /gene="glnA" /locus_tag="BSU_17460" /old_locus_tag="BSU17460" /EC_number="6.3.1.2" /function="16.2: Construct biomass (Anabolism)" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:13737, 11719184, 12142436, 16055443, 16885465, 19233925, 19251843" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 13737, 11719184, 12142436, 16055443, 16885465, 19233925, 19251843; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="glutamine synthetase" /protein_id="NP_389628.1" /db_xref="EnsemblGenomes-Gn:BSU17460" /db_xref="EnsemblGenomes-Tr:CAB13630" /db_xref="GOA:P12425" /db_xref="InterPro:IPR001637" /db_xref="InterPro:IPR004809" /db_xref="InterPro:IPR008146" /db_xref="InterPro:IPR008147" /db_xref="InterPro:IPR014746" /db_xref="InterPro:IPR027302" /db_xref="InterPro:IPR027303" /db_xref="InterPro:IPR036651" /db_xref="PDB:2FWX" /db_xref="PDB:4LNF" /db_xref="PDB:4LNI" /db_xref="PDB:4LNK" /db_xref="PDB:4LNN" /db_xref="PDB:4LNO" /db_xref="PDB:4S0R" /db_xref="SubtiList:BG10425" /db_xref="UniProtKB/Swiss-Prot:P12425" /translation="MAKYTREDIEKLVKEENVKYIRLQFTDILGTIKNVEIPVSQLGK ALDNKVMFDGSSIEGFVRIEESDMYLYPDLNTFVIFPWTAEKGKVARFICDIYNPDGT PFEGDPRNNLKRILKEMEDLGFSDFNLGPEPEFFLFKLDEKGEPTLELNDKGGYFDLA PTDLGENCRRDIVLELEEMGFEIEASHHEVAPGQHEIDFKYAGAVRSCDDIQTFKLVV KTIARKHGLHATFMPKPLFGVNGSGMHCNLSLFKNGVNAFFDENADLQLSETAKHFIA GIVKHATSFTAVTNPTVNSYKRLVPGYEAPCYVAWSAQNRSPLIRIPASRGISTRVEV RSVDPAANPYLALSVLLAAGLDGIKNKLEAPAPIDRNIYVMSKEERMENGIVDLPATL AEALEEFKSNEVMVKALGEHLFEHFIEAKEIEWDMFRTQVHPWEREQYMSQY*" gene 1878425..1879759 /gene="glnA" /locus_tag="BSU_17460" /old_locus_tag="BSU17460" downshifts 1879736 /Source="Nicolas_upshifts" /id="D946" /incds=0 /nref=266 /ntot=287 /MaxReadThrough="5.53201" /MaxDrop="7.28613" /score="29.7599306" /energy="-16.4" /TU="U1394,U1395" /idTUdmin="U1393" /TUdmin=1 /isTUend="TRUE" S_feature 1879781..1880041 /Source="Nicolas_S_feature" /locus_tag="new_1879781_1880041" /HighExp="Cold, BT, LBGtran, G135, G180, Etha, G150, LBGexp, Oxctl, dia15" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigL, SigA" /TUshortPSig="0.777, 1" /TUlongSig="SigA" /TUlongPSig=1 /label="S625" promotor_-35 1880016..1880023 /Source="Nicolas_upshift_promotors" /id="U1396" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.845154845154845" /psig="0.997002997002997" /xcortree=3171 /SigmaFactorBS="agcaataataagatgagtaaggtagatgtttatCATTGACAt cataaccaaatgaATCCATAATTACGTTGAAATctaaatcaattttcaaaaaggagat t" /listShort="ynxB, S626, ynzF, ynzG" /listLong="S627, ynaB, ynaC" /label="promotor_-35" promotor_-10 1880038..1880057 /Source="Nicolas_upshift_promotors" /id="U1396" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.845154845154845" /psig="0.997002997002997" /xcortree=3171 /SigmaFactorBS="agcaataataagatgagtaaggtagatgtttatCATTGACAt cataaccaaatgaATCCATAATTACGTTGAAATctaaatcaattttcaaaaaggagat t" /listShort="ynxB, S626, ynzF, ynzG" /listLong="S627, ynaB, ynaC" /label="promotor_-10" upshifts 1880043 /Source="Nicolas_upshifts" /id="U1396" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.845154845154845" /psig="0.997002997002997" /xcortree=3171 /SigmaFactorBS="agcaataataagatgagtaaggtagatgtttatCATTGACAt cataaccaaatgaATCCATAATTACGTTGAAATctaaatcaattttcaaaaaggagat t" /listShort="ynxB, S626, ynzF, ynzG" /listLong="S627, ynaB, ynaC" CDS 1880087..1880377 /gene="ynxB" /locus_tag="BSU_17470" /old_locus_tag="BSU17470" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type h : extrachromosomal origin" /codon_start=1 /transl_table=11 /product="putative phage protein; defective, phage region" /protein_id="NP_389629.1" /db_xref="EnsemblGenomes-Gn:BSU17470" /db_xref="EnsemblGenomes-Tr:CAB13631" /db_xref="GOA:P31844" /db_xref="SubtiList:BG11074" /db_xref="UniProtKB/Swiss-Prot:P31844" /translation="MKKLTIFSGGLGAVFSVLAQLFAVIDDSYTLGNLWFLGALAGII TMLASIQTNNKPVFSILLIASSVIGLLGTGLVYIIPTLFNIIIIYKFSKVSQ*" gene 1880087..1880377 /gene="ynxB" /locus_tag="BSU_17470" /old_locus_tag="BSU17470" S_feature 1880378..1880622 /Source="Nicolas_S_feature" /locus_tag="new_1880378_1880622" /HighExp="Cold, M9-stat, BC, B60, LPhT, T0.30H, LBGstat, LoTm, S4, T1.30H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.49198399999999998" /TUshortSig="SigA, SigL, SigA" /TUshortPSig="0.997, 0.777, 1" /TUlongSig="SigA" /TUlongPSig=1 /label="S626" CDS 1880623..1880967 /gene="ynzF" /locus_tag="BSU_17480" /old_locus_tag="BSU17480" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type h : extrachromosomal origin" /codon_start=1 /transl_table=11 /product="putative phage protein; defective phage region" /protein_id="NP_389630.1" /db_xref="EnsemblGenomes-Gn:BSU17480" /db_xref="EnsemblGenomes-Tr:CAB13632" /db_xref="SubtiList:BG13469" /db_xref="UniProtKB/Swiss-Prot:O31799" /translation="MWKALSQLLKKQKNQSPSDEDYIQIPELEVKVLGMLHSINIDLV NVIAQAEKSKEFIGQIEGIWHSIANQFYSLAQGFENEDINKLSADLDHAAATWEAVAN KAKEFVTNSYQG*" gene 1880623..1880967 /gene="ynzF" /locus_tag="BSU_17480" /old_locus_tag="BSU17480" downshifts 1880945 /Source="Nicolas_upshifts" /id="D947" /incds=0 /nref=31 /ntot=125 /MaxReadThrough="3.06401" /MaxDrop="4.27622" /score="-0.54122646" /energy="-8.3" /TU="U1394,U1396" /idTUdmin="U1394" /TUdmin="-440" /isTUend="FALSE" CDS 1881098..1881349 /gene="ynzG" /locus_tag="BSU_17490" /old_locus_tag="BSU17490" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type h : extrachromosomal origin" /codon_start=1 /transl_table=11 /product="putative phage protein; defective phage region" /protein_id="NP_389631.1" /db_xref="EnsemblGenomes-Gn:BSU17490" /db_xref="EnsemblGenomes-Tr:CAB13633" /db_xref="SubtiList:BG13470" /db_xref="UniProtKB/Swiss-Prot:O31800" /translation="MLGINVEKSNENLIINWQLSKIEIPIKEINDVFLDPNYGGEEKS AVRIGFPYGSTDRVVIKTARNTYILFTTNPALIMSKIVS*" gene 1881098..1881349 /gene="ynzG" /locus_tag="BSU_17490" /old_locus_tag="BSU17490" promotor_-35 1881375..1881382 /Source="Nicolas_upshift_promotors" /id="U1397" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.96003996003996" /psig=1 /xcortree=3172 /SigmaFactorBS="ttaataaacagtttatgtcccttttaaatTTATCTATtaatg ttctgTGTGGTAAAATTTAGTGAGAtgatttaaggaggaggagcatttatggaagaaa t" /listShort="S627, ynaB, ynaC, ynaD" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1881393..1881412 /Source="Nicolas_upshift_promotors" /id="U1397" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.96003996003996" /psig=1 /xcortree=3172 /SigmaFactorBS="ttaataaacagtttatgtcccttttaaatTTATCTATtaatg ttctgTGTGGTAAAATTTAGTGAGAtgatttaaggaggaggagcatttatggaagaaa t" /listShort="S627, ynaB, ynaC, ynaD" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 1881406..1881535 /Source="Nicolas_S_feature" /locus_tag="new_1881406_1881535" /HighExp="LoTm, Etha, LPhT, B60, M9-stat, T3.0H, T3.30H, Salt, T4.0H, T1.30H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.968584" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="SigA, SigA, SigA" /TUlongPSig="0.997, 1, 1" /label="S627" upshifts 1881406 /Source="Nicolas_upshifts" /id="U1397" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.96003996003996" /psig=1 /xcortree=3172 /SigmaFactorBS="ttaataaacagtttatgtcccttttaaatTTATCTATtaatg ttctgTGTGGTAAAATTTAGTGAGAtgatttaaggaggaggagcatttatggaagaaa t" /listShort="S627, ynaB, ynaC, ynaD" /GFF_Attribute="listLong" CDS 1881536..1881970 /gene="ynaB" /locus_tag="BSU_17500" /old_locus_tag="BSU17500" /function="17.2: Prophage functions" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type h : extrachromosomal origin" /codon_start=1 /transl_table=11 /product="putative phage protein; defective phage region" /protein_id="NP_389632.2" /db_xref="EnsemblGenomes-Gn:BSU17500" /db_xref="EnsemblGenomes-Tr:CAB13634" /db_xref="InterPro:IPR018958" /db_xref="SubtiList:BG12254" /db_xref="UniProtKB/Swiss-Prot:P94480" /translation="MEDATFHFKDPASPQEISDIEQKLGVTFPNDYKEFLLQHNGMEM FDGIEILSLEGIIEYNEVQDFPEGYVLIGYHFDGRYVIDTNKSKNGLGYMLYLDSIDD IEDAINLDSNFEIWFDMLVSLNGTKYWEVNPNLQEYYKLVSE*" gene 1881536..1881970 /gene="ynaB" /locus_tag="BSU_17500" /old_locus_tag="BSU17500" CDS 1882040..1882831 /gene="ynaC" /locus_tag="BSU_17510" /old_locus_tag="BSU17510" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein; defective phage region" /protein_id="NP_389633.1" /db_xref="EnsemblGenomes-Gn:BSU17510" /db_xref="EnsemblGenomes-Tr:CAB13635" /db_xref="SubtiList:BG12255" /db_xref="UniProtKB/Swiss-Prot:P94481" /translation="MTIYEQIKDALKNKINELVSPQEVKKTLQEKYGTNPDSIILSDY CYNRYNKGISFNKHLFEYMNRSSYKYLGENSLYTGLIFRKSKGEDKEVIVGEWVNGVK SLREASVTNNQINDQAEIISKEQLVNLYNEYNQILRYEMNVLNCKPTELRHLIGRIGE FICAIQTNGTLARQTNQHGFDVVSDGRRISVKTTAQSSGFISINKNTFYDFDDFFVVQ YVNDDFKVIFFGSKEEVQKISRIYGSQYEVEISLLKKLNKEYQLN*" gene 1882040..1882831 /gene="ynaC" /locus_tag="BSU_17510" /old_locus_tag="BSU17510" promotor_-10 complement(1882148..1882167) /Source="Nicolas_upshift_promotors" /id="U1398" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.702297702297702" /psig="0.988011988011988" /xcortree=382 /SigmaFactorBS="gaggtgcttattaaaagaaatccccttattaTACcggttata acaataaTCTGATAAAATAATGCTATCcggattagttccgtatttttcttgaagggtt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1882156) /Source="Nicolas_upshifts" /id="U1398" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.702297702297702" /psig="0.988011988011988" /xcortree=382 /SigmaFactorBS="gaggtgcttattaaaagaaatccccttattaTACcggttata acaataaTCTGATAAAATAATGCTATCcggattagttccgtatttttcttgaagggtt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(1882183..1882185) /Source="Nicolas_upshift_promotors" /id="U1398" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.702297702297702" /psig="0.988011988011988" /xcortree=382 /SigmaFactorBS="gaggtgcttattaaaagaaatccccttattaTACcggttata acaataaTCTGATAAAATAATGCTATCcggattagttccgtatttttcttgaagggtt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 1882827 /Source="Nicolas_upshifts" /id="D948" /incds=0 /nref=10 /ntot=182 /MaxReadThrough="4.47202" /MaxDrop="6.29359" /score="3.60743536" /energy="-14.4" /TU="U1397" /idTUdmin="U1397" /TUdmin="-836" /isTUend="FALSE" downshifts 1882893 /Source="Nicolas_upshifts" /id="D949" /incds=0 /nref=1 /ntot=65 /MaxReadThrough="3.36892" /MaxDrop="4.40772" /score="3.60743536" /energy="-14.4" /TU="U1397" /idTUdmin="U1397" /TUdmin="-770" /isTUend="FALSE" promotor_-35 1883104..1883112 /Source="Nicolas_upshift_promotors" /id="U1399" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.628371628371628" /psig="0.628371628371628" /xcortree=3199 /SigmaFactorBS="gcaatattgttgaataagaatagttttaaAGAGGTTATtgtt gtcttcaTATTGAAATAAAGATTAAGtatattagaggggagttgctttaatgcacata a" /listShort="ynaD" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1883124..1883142 /Source="Nicolas_upshift_promotors" /id="U1399" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.628371628371628" /psig="0.628371628371628" /xcortree=3199 /SigmaFactorBS="gcaatattgttgaataagaatagttttaaAGAGGTTATtgtt gtcttcaTATTGAAATAAAGATTAAGtatattagaggggagttgctttaatgcacata a" /listShort="ynaD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1883135 /Source="Nicolas_upshifts" /id="U1399" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.628371628371628" /psig="0.628371628371628" /xcortree=3199 /SigmaFactorBS="gcaatattgttgaataagaatagttttaaAGAGGTTATtgtt gtcttcaTATTGAAATAAAGATTAAGtatattagaggggagttgctttaatgcacata a" /listShort="ynaD" /GFF_Attribute="listLong" CDS 1883166..1883678 /gene="ynaD" /locus_tag="BSU_17520" /old_locus_tag="BSU17520" /EC_number="2.3.1.-" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative N-acetyltransferase; putative phage region" /protein_id="NP_389634.1" /db_xref="EnsemblGenomes-Gn:BSU17520" /db_xref="EnsemblGenomes-Tr:CAB13636" /db_xref="GOA:P94482" /db_xref="InterPro:IPR000182" /db_xref="InterPro:IPR016181" /db_xref="SubtiList:BG12256" /db_xref="UniProtKB/Swiss-Prot:P94482" /translation="MHITTKRLLIREFEFKDWQAVYEYTSDSNVMKYIPEGVFTEEDA KAFVNKNKGDNAEKFPVILRDEDCLIGHIVFYKYFGEHTYEIGWVFNPNYQNKGYASE AAQAILEYGFKEMNLHRIIATCQPENIPSYRVMKKIGMRREGFFKKCIPKGNEWWDEY YYAILEEEWN*" gene 1883166..1883678 /gene="ynaD" /locus_tag="BSU_17520" /old_locus_tag="BSU17520" promotor_-35 1884125..1884131 /Source="Nicolas_upshift_promotors" /id="U1400" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.665334665334665" /psig="0.994005994005994" /xcortree=3213 /SigmaFactorBS="aaagtgaacctgccacagatgttcattatcttttagggggtt ccaaaaagaccgtattccTATCGATcgctcagagtgaaAATGGTATACTAAAGTTACA a" /listShort="S628, ynaE, S629, ynaF, ynaG, ynzI, S630, ynaI, S631" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 1884125 /Source="Nicolas_upshifts" /id="U1400" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.665334665334665" /psig="0.994005994005994" /xcortree=3213 /SigmaFactorBS="aaagtgaacctgccacagatgttcattatcttttagggggtt ccaaaaagaccgtattccTATCGATcgctcagagtgaaAATGGTATACTAAAGTTACA a" /listShort="S628, ynaE, S629, ynaF, ynaG, ynzI, S630, ynaI, S631" /GFF_Attribute="listLong" promotor_-35 1884127..1884131 /Source="Nicolas_upshift_promotors" /id="U1401" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.906093906093906" /psig=1 /xcortree=3221 /SigmaFactorBS="aaaaagaccgtattcctaTCGATcgctcagagtgaaAATGGT ATACTAAAGTTACAatcacaggaaggaattacaatttttttagatctacataaaatca t" /listShort="S628, ynaE, S629, ynaF, ynaG, ynzI, S630, ynaI" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1884145..1884164 /Source="Nicolas_upshift_promotors" /id="U1400" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.665334665334665" /psig="0.994005994005994" /xcortree=3213 /SigmaFactorBS="aaagtgaacctgccacagatgttcattatcttttagggggtt ccaaaaagaccgtattccTATCGATcgctcagagtgaaAATGGTATACTAAAGTTACA a" /listShort="S628, ynaE, S629, ynaF, ynaG, ynzI, S630, ynaI, S631" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-10 1884145..1884164 /Source="Nicolas_upshift_promotors" /id="U1401" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.906093906093906" /psig=1 /xcortree=3221 /SigmaFactorBS="aaaaagaccgtattcctaTCGATcgctcagagtgaaAATGGT ATACTAAAGTTACAatcacaggaaggaattacaatttttttagatctacataaaatca t" /listShort="S628, ynaE, S629, ynaF, ynaG, ynzI, S630, ynaI" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 1884169..1884237 /Source="Nicolas_S_feature" /locus_tag="new_1884169_1884237" /HighExp="T1.30H, M9-stat, Lbtran, M0t90, T0.30H, T1.0H, T2.30H, Lbstat, T3.0H, S2" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="1, 0.994" /TUlongSig="NA" /TUlongPSig="NA" /label="S628" upshifts 1884169 /Source="Nicolas_upshifts" /id="U1401" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.906093906093906" /psig=1 /xcortree=3221 /SigmaFactorBS="aaaaagaccgtattcctaTCGATcgctcagagtgaaAATGGT ATACTAAAGTTACAatcacaggaaggaattacaatttttttagatctacataaaatca t" /listShort="S628, ynaE, S629, ynaF, ynaG, ynzI, S630, ynaI" /GFF_Attribute="listLong" CDS 1884238..1884879 /gene="ynaE" /locus_tag="BSU_17530" /old_locus_tag="BSU17530" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_389635.1" /db_xref="EnsemblGenomes-Gn:BSU17530" /db_xref="EnsemblGenomes-Tr:CAB13637" /db_xref="InterPro:IPR024976" /db_xref="SubtiList:BG12257" /db_xref="UniProtKB/Swiss-Prot:P94483" /translation="MNLIGYIEERFQNLELIPSIYNQWGTGIHFCLGENIYQLKANEE LNLKMFRIVYEQTSIIFNELFEQNDDIFLVTNMYKHKKKEKCIRKLKVYQPFLKCKNH LNQIMVKTYPYPFEINKAEEYEMQQFSLLCKPRDLRVTELLKAASNEDFPQKPKFGGY SIDYPDVFFVNITKDIIFFIYDDRGCEVIAHDFKRIRPLYEKYHDWVEEYKCM*" gene 1884238..1884879 /gene="ynaE" /locus_tag="BSU_17530" /old_locus_tag="BSU17530" S_feature 1884880..1884967 /Source="Nicolas_S_feature" /locus_tag="new_1884880_1884967" /HighExp="M0t90, Lbtran, Lbstat, T1.30H, S2, T1.0H, T0.30H, MG 150, M9-stat, S1" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="1, 0.994" /TUlongSig="NA" /TUlongPSig="NA" /label="S629" CDS 1884968..1885321 /gene="ynaF" /locus_tag="BSU_17540" /old_locus_tag="BSU17540" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein; defective phage region" /protein_id="NP_389636.1" /db_xref="EnsemblGenomes-Gn:BSU17540" /db_xref="EnsemblGenomes-Tr:CAB13638" /db_xref="SubtiList:BG12258" /db_xref="UniProtKB/Swiss-Prot:P94484" /translation="MVLCDDERSAFLLVLDERLVDFDSQGGNHISVYLVTHFELSDQS YKDVLSFNDDLLGMEHNCSYAMDILSVKEELDFDFPFNMLAIKSYVQELIKMLGIDIT LPEMKERDFDKLSQN*" gene 1884968..1885321 /gene="ynaF" /locus_tag="BSU_17540" /old_locus_tag="BSU17540" CDS 1885365..1885640 /gene="ynaG" /locus_tag="BSU_17550" /old_locus_tag="BSU17550" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein; defective phage region" /protein_id="NP_389637.1" /db_xref="EnsemblGenomes-Gn:BSU17550" /db_xref="EnsemblGenomes-Tr:CAB13639" /db_xref="GOA:P94485" /db_xref="SubtiList:BG12259" /db_xref="UniProtKB/Swiss-Prot:P94485" /translation="MNVKKAAAVFSITIPIISAILIINFFTGFMSIPWQGMPVFFPLL LSPIGIILAFVSIKTNKRCAVYGIVLNAIMFPFPFFWFIGGALLFGV*" gene 1885365..1885640 /gene="ynaG" /locus_tag="BSU_17550" /old_locus_tag="BSU17550" downshifts complement(1885741) /Source="Nicolas_upshifts" /id="D950" /incds=0 /nref=2 /ntot=57 /MaxReadThrough="1.74772" /MaxDrop="3.30031" /score="-7.48025946" /energy="-14.4" /TU="NA" /idTUdmin="U1402" /TUdmin=308 /isTUend="FALSE" CDS 1885753..1885917 /gene="ynzI" /locus_tag="BSU_17559" /old_locus_tag="BSU17559" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein; defective phage region" /protein_id="YP_003097730.1" /db_xref="EnsemblGenomes-Gn:BSU17559" /db_xref="EnsemblGenomes-Tr:CAX52623" /db_xref="GOA:C0H415" /db_xref="UniProtKB/Swiss-Prot:C0H415" /translation="MDRKKDEIQRKYREQMREKKEREKEDGSSHTFEIVVVLAIIILM FFFNSVFKAF*" gene 1885753..1885917 /gene="ynzI" /locus_tag="BSU_17559" /old_locus_tag="BSU17559" S_feature 1885918..1886056 /Source="Nicolas_S_feature" /locus_tag="new_1885918_1886056" /HighExp="M0t90, Lbstat, S1, Lbtran, S2, M40t90, T1.30H, Glu, T1.0H, M40t45" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="1, 0.994" /TUlongSig="NA" /TUlongPSig="NA" /label="S630" CDS 1886057..1886527 /gene="ynaI" /locus_tag="BSU_17560" /old_locus_tag="BSU17560" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein; defective phage region" /protein_id="NP_389638.3" /db_xref="EnsemblGenomes-Gn:BSU17560" /db_xref="EnsemblGenomes-Tr:CAB13640" /db_xref="SubtiList:BG12261" /db_xref="UniProtKB/Swiss-Prot:P94487" /translation="MKLYNEFINIAKTFNKELDIIPLLYGSLGLEKVTGLDFSPEDID LLIPLIFLEEKWEKLKKVMELHGYKMVDLHEHEFKKTNTKIGISYIEDLKPFADVDYN NLEIFEDGGAKYHLLTIDDYLKIYKKSLLDGYRRRKKNHKDQSKINILNKLIRN*" gene 1886057..1886527 /gene="ynaI" /locus_tag="BSU_17560" /old_locus_tag="BSU17560" S_feature 1886528..1887351 /Source="Nicolas_S_feature" /locus_tag="new_1886528_1887351" /HighExp="Lbstat, M0t90, S8, C30, Pyr, Lbtran, M40t90, S1, M/G, S2" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.994" /TUlongSig="NA" /TUlongPSig="NA" /label="S631" promotor_-10 complement(1886691..1886709) /Source="Nicolas_upshift_promotors" /id="U1402" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.99100899100899" /psig="0.99100899100899" /xcortree=1005 /SigmaFactorBS="gtcatgaattgaaagaacggaatggccagaatagtttatGTT ATAagtccaaccctacatACATATATCAATACAGGAAagataaataagaagcaaaaat a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1886709) /Source="Nicolas_upshifts" /id="U1402" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.99100899100899" /psig="0.99100899100899" /xcortree=1005 /SigmaFactorBS="gtcatgaattgaaagaacggaatggccagaatagtttatGTT ATAagtccaaccctacatACATATATCAATACAGGAAagataaataagaagcaaaaat a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(1886725..1886730) /Source="Nicolas_upshift_promotors" /id="U1402" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.99100899100899" /psig="0.99100899100899" /xcortree=1005 /SigmaFactorBS="gtcatgaattgaaagaacggaatggccagaatagtttatGTT ATAagtccaaccctacatACATATATCAATACAGGAAagataaataagaagcaaaaat a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" CDS 1887352..1888743 /gene="xynP" /locus_tag="BSU_17570" /old_locus_tag="BSU17570" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 15849754, 16684115, 16850406, 17183216, 20406496; Product type t : transporter" /codon_start=1 /transl_table=11 /product="H+-xyloside symporter" /protein_id="NP_389639.2" /db_xref="EnsemblGenomes-Gn:BSU17570" /db_xref="EnsemblGenomes-Tr:CAB13641" /db_xref="GOA:P94488" /db_xref="InterPro:IPR001927" /db_xref="InterPro:IPR018043" /db_xref="InterPro:IPR020846" /db_xref="InterPro:IPR036259" /db_xref="SubtiList:BG12262" /db_xref="UniProtKB/Swiss-Prot:P94488" /translation="MLSENVKKISMVEKVGYASGDFACNLIYATVSTYLLFFYTDVFG LSAAAAGTMFLVVRIIDALADPFIGTIVDRTNSRFGRFRPYLLFGAFPFVILAILCFT TPDFSDMGKLIYAYITYVGLSLTYTTINVPYGALTSAMTRNNQEVVSITSVRMLFANL GGLVVAFFVPLLAAYLSDTSGNESLGWQLTMGILGMIGGCLLIFCFKSTKERVTLQKS EEKIKFTDIFEQFRVNRPLVVLSIFFIIIFGVNSISNSVGIYYVTYNLEREDLVKWYG LIGSLPALVILPFIPRLHQFLGKKKLLNYALLLNIIGLLALLFVPPSNVYLILVCRLI AAAGSLTAGGYMWALIPETIEYGEYRTGKRMGGLIYAIIGFFFKFGMALGGVVPGLVL DKFGYVANQAQTPAALMGILITTTIIPVFLLVLALIDINFYNLDEKKYKNMVRELENR DKVYLDHIDDFKA*" gene 1887352..1888743 /gene="xynP" /locus_tag="BSU_17570" /old_locus_tag="BSU17570" CDS 1888774..1890375 /gene="xynB" /locus_tag="BSU_17580" /old_locus_tag="BSU17580" /EC_number="3.2.1.37" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1c: Function from experimental evidences in the studied genus; PubMedId: 2440680, 6413490, 7816035, 9286998, 9973552, 16684115, 28066362; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="xylan beta-1,4-xylosidase" /protein_id="NP_389640.2" /db_xref="EnsemblGenomes-Gn:BSU17580" /db_xref="EnsemblGenomes-Tr:CAB13642" /db_xref="GOA:P94489" /db_xref="InterPro:IPR006710" /db_xref="InterPro:IPR013320" /db_xref="InterPro:IPR023296" /db_xref="PDB:1YIF" /db_xref="SubtiList:BG11987" /db_xref="UniProtKB/Swiss-Prot:P94489" /translation="MKITNPVLKGFNPDPSICRAGEDYYIAVSTFEWFPGVQIHHSKD LVNWHLVAHPLQRVSQLDMKGNPNSGGVWAPCLSYSDGKFWLIYTDVKVVDGAWKDCH NYLVTCETINGDWSEPIKLNSSGFDASLFHDTDGKKYLLNMLWDHRIDRHSFGGIVIQ EYSDKEQKLIGKPKVIFEGTDRKLTEAPHLYHIGNYYYLLTAEGGTRYEHAATIARSA NIEGPYEVHPDNPILTSWHDPGNPLQKCGHASIVQTHTDEWYLAHLTGRPIHPDDDSI FQQRGYCPLGRETAIQKLYWKDEWPYVVGGKEGSLEVDAPSIPETIFEATYPEVDEFE DSTLNINFQTLRIPFTNELGSLTQAPNHLRLFGHESLTSTFTQAFVARRWQSLHFEAE TAVEFYPENFQQAAGLVNYYNTENWTALQVTHDEELGRILELTICDNFSFSQPLNNKI VIPREVKYVYLRVNIEKDKYYYFYSFNKEDWHKIDIALESKKLSDDYIRGGGFFTGAF VGMQCQDTSGNHIPADFRYFRYKEK*" gene 1888774..1890375 /gene="xynB" /locus_tag="BSU_17580" /old_locus_tag="BSU17580" S_feature complement(1888890..1889195) /Source="Nicolas_S_feature" /locus_tag="new_1888890_1889195_c" /HighExp="S8, S6, S7, BT, C30, S5, Pyr, S4, B36, BC" /AntisenseName="xynB" /AntisenseCor="6.2527836498644102E-2" /AntisenseRegPval="-0.5" /CDS_PredictionProba="NA" /TUshortSig="SigK" /TUshortPSig="0.985" /TUlongSig="NA" /TUlongPSig="NA" /label="S632" promotor_-10 complement(1889190..1889209) /Source="Nicolas_upshift_promotors" /id="U1403" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.985014985014985" /psig="0.985014985014985" /xcortree=1333 /SigmaFactorBS="tcctgtataacaattcctccaaatGAGTGCCGAtcaatacgg tgatCCCATAACATATTTAATAAAtacttttttccatccgtatcatggaacaaagaag c" /listShort="S632" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1889195) /Source="Nicolas_upshifts" /id="U1403" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.985014985014985" /psig="0.985014985014985" /xcortree=1333 /SigmaFactorBS="tcctgtataacaattcctccaaatGAGTGCCGAtcaatacgg tgatCCCATAACATATTTAATAAAtacttttttccatccgtatcatggaacaaagaag c" /listShort="S632" /GFF_Attribute="listLong" promotor_-35 complement(1889223..1889231) /Source="Nicolas_upshift_promotors" /id="U1403" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.985014985014985" /psig="0.985014985014985" /xcortree=1333 /SigmaFactorBS="tcctgtataacaattcctccaaatGAGTGCCGAtcaatacgg tgatCCCATAACATATTTAATAAAtacttttttccatccgtatcatggaacaaagaag c" /listShort="S632" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 1890373 /Source="Nicolas_upshifts" /id="D951" /incds=0 /nref=2 /ntot=53 /MaxReadThrough="1.32947" /MaxDrop="3.8449" /score="13.0570501" /energy="-10.2" /TU="NA" /idTUdmin="U1400" /TUdmin=3190 /isTUend="FALSE" CDS complement(1890512..1891666) /gene="xylR" /locus_tag="BSU_17590" /old_locus_tag="BSU17590" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 1588910, 1719948, 2544559, 7559331; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator" /protein_id="NP_389641.3" /db_xref="EnsemblGenomes-Gn:BSU17590" /db_xref="EnsemblGenomes-Tr:CAB13643" /db_xref="GOA:P94490" /db_xref="InterPro:IPR000600" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG11986" /db_xref="UniProtKB/Swiss-Prot:P94490" /translation="MDIADQTFVKKVNQKLLLKEILKNSPISRAKLSEMTGLNKSTVS SQVNTLMKESMVFEIGQGQSSGGRRPVMLVFNKKAGYSVGIDVGVDYINGILTDLEGT IVLDQYRHLESNSPEITKDILIDMIHHFITQMPQSPYGLIGIGICVPGLIDKDQKIVF TPNSNWRDIDLKSSIQEKYNVPVFIENEANAGAYGEKVFGAAKNHDNIIYVSISTGIG IGVIINNHLYRGVSGFSGEMGHMTIDFNGPKCSCGNRGCWELYASEKALLKSLQTKEK KLSYQDIINLAHLNDIGTLNALQNFGFYLGIGLTNILNTFNPQAVILRNSIIESHPMV LNSMRSEVSSRVYSQLGNSYELLPSSLGQNAPALGMSSIVIDHFLDMITM*" gene complement(1890512..1891666) /gene="xylR" /locus_tag="BSU_17590" /old_locus_tag="BSU17590" downshifts complement(1890515) /Source="Nicolas_upshifts" /id="D952" /incds=0 /nref=9 /ntot=198 /MaxReadThrough="2.56326" /MaxDrop="4.09398" /score="19.297583" /energy="-7.4" /TU="NA" /idTUdmin="U1405" /TUdmin=0 /isTUend="TRUE" S_feature complement(1891565..1891743) /Source="Nicolas_S_feature" /locus_tag="new_1891565_1891743_c" /HighExp="dia15, Etha, dia5, dia0, Cold, LBGstat, Lbexp, M0t45, Diami, LBGexp" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S633" promotor_-35 1891711..1891717 /Source="Nicolas_upshift_promotors" /id="U1404" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.48951048951049" /psig="0.487512487512487" /xcortree=661 /SigmaFactorBS="ccatttgtttaatctttaaattaagtatcaacatAGTACATa gcgaatctTCCCTTTATTATATCTAatgtgttcataaaaaactaaaaaaaatattgaa a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(1891726..1891745) /Source="Nicolas_upshift_promotors" /id="U1405" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.583416583416583" /psig=1 /xcortree=1893 /SigmaFactorBS="ttcatcttatataacctcgtcagtattttcaatattttttTT AGttttttatgaacacATTAGATATAATAAAGGGAAgattcgctatgtactatgttga t" /listShort="S633, xylR" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-10 1891727..1891743 /Source="Nicolas_upshift_promotors" /id="U1404" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.48951048951049" /psig="0.487512487512487" /xcortree=661 /SigmaFactorBS="ccatttgtttaatctttaaattaagtatcaacatAGTACATa gcgaatctTCCCTTTATTATATCTAatgtgttcataaaaaactaaaaaaaatattgaa a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1891737 /Source="Nicolas_upshifts" /id="U1404" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.48951048951049" /psig="0.487512487512487" /xcortree=661 /SigmaFactorBS="ccatttgtttaatctttaaattaagtatcaacatAGTACATa gcgaatctTCCCTTTATTATATCTAatgtgttcataaaaaactaaaaaaaatattgaa a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" upshifts complement(1891743) /Source="Nicolas_upshifts" /id="U1405" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.583416583416583" /psig=1 /xcortree=1893 /SigmaFactorBS="ttcatcttatataacctcgtcagtattttcaatattttttTT AGttttttatgaacacATTAGATATAATAAAGGGAAgattcgctatgtactatgttga t" /listShort="S633, xylR" /GFF_Attribute="listLong" promotor_-35 complement(1891760..1891763) /Source="Nicolas_upshift_promotors" /id="U1405" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.583416583416583" /psig=1 /xcortree=1893 /SigmaFactorBS="ttcatcttatataacctcgtcagtattttcaatattttttTT AGttttttatgaacacATTAGATATAATAAAGGGAAgattcgctatgtactatgttga t" /listShort="S633, xylR" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1891770..1891777 /Source="Nicolas_upshift_promotors" /id="U1406" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.973026973026973" /psig=1 /xcortree=1568 /SigmaFactorBS="atgtgttcataaaaaactaaaaaaaaTATTGAAAatactgac gaggttATATAAGATGAAAATAAGTTagtttgtttaaacaacaaactaataggtgatg t" /listShort="S634, xylA, S635, xylB, S636" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1891792..1891811 /Source="Nicolas_upshift_promotors" /id="U1406" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.973026973026973" /psig=1 /xcortree=1568 /SigmaFactorBS="atgtgttcataaaaaactaaaaaaaaTATTGAAAatactgac gaggttATATAAGATGAAAATAAGTTagtttgtttaaacaacaaactaataggtgatg t" /listShort="S634, xylA, S635, xylB, S636" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 1891803..1891907 /Source="Nicolas_S_feature" /locus_tag="new_1891803_1891907" /HighExp="dia15, dia0, Lbexp, dia5, B60, Sw, G150, LPhT, Mt0, M0t45" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S634" upshifts 1891804 /Source="Nicolas_upshifts" /id="U1406" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.973026973026973" /psig=1 /xcortree=1568 /SigmaFactorBS="atgtgttcataaaaaactaaaaaaaaTATTGAAAatactgac gaggttATATAAGATGAAAATAAGTTagtttgtttaaacaacaaactaataggtgatg t" /listShort="S634, xylA, S635, xylB, S636" /GFF_Attribute="listLong" CDS 1891908..1893245 /gene="xylA" /locus_tag="BSU_17600" /old_locus_tag="BSU17600" /EC_number="5.3.1.5" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:7663444, 8132469" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7663444, 8132469; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="xylose isomerase" /protein_id="NP_389642.2" /db_xref="EnsemblGenomes-Gn:BSU17600" /db_xref="EnsemblGenomes-Tr:CAB13644" /db_xref="GOA:P0CI80" /db_xref="InterPro:IPR001998" /db_xref="InterPro:IPR013022" /db_xref="InterPro:IPR013452" /db_xref="InterPro:IPR036237" /db_xref="SubtiList:BG10806" /db_xref="UniProtKB/Swiss-Prot:P0CI80" /translation="MAQSHSSSINYFGSANKVVYEGKDSTNPLAFKYYNPQEVIGGKT LKEHLRFSIAYWHTFTADGTDVFGAATMQRPWDHYKGMDLAKMRVEAAFEMFEKLDAP FFAFHDRDIAPEGSTLKETNQNLDMIMGMIKDYMRNSGVKLLWNTANMFTNPRFVHGA ATSCNADVFAYAAAQVKKGLETAKELGAENYVFWGGREGYETLLNTDLKFELDNLARF MHMAVDYAKEIGYTGQFLIEPKPKEPTTHQYDTDAATTIAFLKQYGLDNHFKLNLEAN HATLAGHTFEHELRMARVHGLLGSVDANQGHPLLGWDTDEFPTDLYSTTLAMYEILQN GGLGSGGLNFDAKVRRSSFEPDDLIYAHIAGMDAFARGLKVAHKLIEDRVFEDVIQHR YRSFTEGIGLEIIEGRANFHTLEQYALNHKSIKNESGRQEKLKAILNQYILEV*" gene 1891908..1893245 /gene="xylA" /locus_tag="BSU_17600" /old_locus_tag="BSU17600" S_feature 1893246..1893320 /Source="Nicolas_S_feature" /locus_tag="new_1893246_1893320" /HighExp="dia0, dia15, Sw, Lbexp, dia5, B60, Mt0, M0t45, G150, LPhT" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S635" downshifts 1893277 /Source="Nicolas_upshifts" /id="D953" /incds=0 /nref=1 /ntot=3 /MaxReadThrough="4.89699" /MaxDrop="3.40404" /score="13.0570501" /energy="-10.2" /TU="U1406" /idTUdmin="U1406" /TUdmin="-1892" /isTUend="FALSE" CDS 1893396..1894895 /gene="xylB" /locus_tag="BSU_17610" /old_locus_tag="BSU17610" /EC_number="2.7.1.17" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 1660563, 8866023, 27467131; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="xylulose kinase" /protein_id="NP_389643.1" /db_xref="EnsemblGenomes-Gn:BSU17610" /db_xref="EnsemblGenomes-Tr:CAB13645" /db_xref="GOA:P39211" /db_xref="InterPro:IPR000577" /db_xref="InterPro:IPR006000" /db_xref="InterPro:IPR018483" /db_xref="InterPro:IPR018484" /db_xref="InterPro:IPR018485" /db_xref="SubtiList:BG10807" /db_xref="UniProtKB/Swiss-Prot:P39211" /translation="MKYVIGIDLGTSAVKTILVNQNGKVCAETSKRYPLIQEKAGYSE QNPEDWVQQTIEALAELVSISNVQAKDIDGISYSGQMHGLVLLDQDRQVLRNAILWND TRTTPQCIRMTEKFGDHLLDITKNRVLEGFTLPKMLWVKEHEPELFKKTAVFLLPKDY VRFRMTGVIHTEYSDAAGTLLLHITRKEWSNDICNQIGISADICPPLVESHDCVGSLL PHVAAKTGLLEKTKVYAGGADNACGAIGAGILSSGKTLCSIGTSGVILSYEEEKERDF KGKVHFFNHGKKDSFYTMGVTLAAGYSLDWFKRTFAPNESFEQLLQGVEAIPIGANGL LYTPYLVGERTPHADSSIRGSLIGMDGAHNRKHFLRAIMEGITFSLHESIELFREAGK SVHTVVSIGGGAKNDTWLQMQADIFNTRVIKLENEQGPAMGAAMLAAFGSGWFESLEE CAEQFIREAAAFYPKAQNVQKYKTLFDLYKNIYTHTKDLNTALKSFRKN*" gene 1893396..1894895 /gene="xylB" /locus_tag="BSU_17610" /old_locus_tag="BSU17610" S_feature 1894896..1895211 /Source="Nicolas_S_feature" /locus_tag="new_1894896_1895211" /HighExp="dia0, dia15, Lbexp, dia5, Mt0, M0t45, G150, Etha, Diami, Lbstat" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.51323200000000002" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S636" downshifts 1895169 /Source="Nicolas_upshifts" /id="D954" /incds=0 /nref=60 /ntot=197 /MaxReadThrough="0.61776" /MaxDrop="5.13425" /score="13.0570501" /energy="-10.2" /TU="NA" /idTUdmin="U1406" /TUdmin=0 /isTUend="TRUE" CDS complement(1895378..1896013) /gene="yncB" /locus_tag="BSU_17620" /old_locus_tag="BSU17620" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:11584000" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11584000; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="DNA nuclease, lipoprotein (phage origin)" /protein_id="NP_389644.1" /db_xref="EnsemblGenomes-Gn:BSU17620" /db_xref="EnsemblGenomes-Tr:CAB13646" /db_xref="GOA:P94492" /db_xref="InterPro:IPR002071" /db_xref="InterPro:IPR016071" /db_xref="InterPro:IPR035437" /db_xref="SubtiList:BG12265" /db_xref="UniProtKB/Swiss-Prot:P94492" /translation="MKKILISMIAIVLSITLAACGSNHAAKNHSDSNGTEQVSQDTHS NEYNQTEQKAGTPHSKNQKKLVNVTLDRAIDGDTIKVIYNGKKDTVRYLLVDTPETKK PNSCVQPYGEDASKRNKELVNSGKLQLEFDKGDRRDKYGRLLAYVYVDGKSVQETLLK EGLARVAYVYEPNTKYIDQFRLDEQEAKSDKLSIWSKSGYVTNRGFNGCVK*" gene complement(1895378..1896013) /gene="yncB" /locus_tag="BSU_17620" /old_locus_tag="BSU17620" promotor_-10 complement(1896050..1896069) /Source="Nicolas_upshift_promotors" /id="U1407" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.936063936063936" /psig="0.999000999001" /xcortree=2438 /SigmaFactorBS="gagtgttataagttcccttgaagttttcCATTCACAaaaaat gtccatatCGTTATAATGATGATGTTTAatcgcgaaaagagaaaatgataaagaggga a" /listShort="yncB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1896059) /Source="Nicolas_upshifts" /id="U1407" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.936063936063936" /psig="0.999000999001" /xcortree=2438 /SigmaFactorBS="gagtgttataagttcccttgaagttttcCATTCACAaaaaat gtccatatCGTTATAATGATGATGTTTAatcgcgaaaagagaaaatgataaagaggga a" /listShort="yncB" /GFF_Attribute="listLong" promotor_-35 complement(1896084..1896091) /Source="Nicolas_upshift_promotors" /id="U1407" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.936063936063936" /psig="0.999000999001" /xcortree=2438 /SigmaFactorBS="gagtgttataagttcccttgaagttttcCATTCACAaaaaat gtccatatCGTTATAATGATGATGTTTAatcgcgaaaagagaaaatgataaagaggga a" /listShort="yncB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1896201..1896208 /Source="Nicolas_upshift_promotors" /id="U1408" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.982017982017982" /psig=1 /xcortree=321 /SigmaFactorBS="ccatcacatagcggaaataaataatcctgaaaataaTATTGA CTgaaaatgcttttagAATTATGATAATATGAGAAAtgacaataatgtgacaaagaca t" /listShort="S637, yncC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1896223..1896242 /Source="Nicolas_upshift_promotors" /id="U1408" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.982017982017982" /psig=1 /xcortree=321 /SigmaFactorBS="ccatcacatagcggaaataaataatcctgaaaataaTATTGA CTgaaaatgcttttagAATTATGATAATATGAGAAAtgacaataatgtgacaaagaca t" /listShort="S637, yncC" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 1896225..1896423 /Source="Nicolas_S_feature" /locus_tag="new_1896225_1896423" /HighExp="T0.30H, Lbtran, T1.0H, M9-stat, M0t90, T1.30H, M40t90, T2.0H, T0.0H, T2.30H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S637" upshifts 1896225 /Source="Nicolas_upshifts" /id="U1408" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.982017982017982" /psig=1 /xcortree=321 /SigmaFactorBS="ccatcacatagcggaaataaataatcctgaaaataaTATTGA CTgaaaatgcttttagAATTATGATAATATGAGAAAtgacaataatgtgacaaagaca t" /listShort="S637, yncC" /GFF_Attribute="listLong" CDS 1896424..1897839 /gene="yncC" /locus_tag="BSU_17630" /old_locus_tag="BSU17630" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406, 22900538, 23569278; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative sugar transporter" /protein_id="NP_389645.2" /db_xref="EnsemblGenomes-Gn:BSU17630" /db_xref="EnsemblGenomes-Tr:CAB13647" /db_xref="GOA:P94493" /db_xref="InterPro:IPR003663" /db_xref="InterPro:IPR005828" /db_xref="InterPro:IPR005829" /db_xref="InterPro:IPR020846" /db_xref="InterPro:IPR036259" /db_xref="SubtiList:BG12266" /db_xref="UniProtKB/Swiss-Prot:P94493" /translation="MDMNEHRNRRLKLIMISATFGGLLFGYDTGVINGALPFMARPDQ LDLTPVTEGLVTSILLLGAAFGALLCGRLADRYGRRKMILNLSFLFFLASLGTALAPN VFIMAVFRFLLGLAVGGASAMVPAFLAEMAPHEKRGRMVTQNELMIVGGQFLAYVFNA ILGVTMANTGHVWRYMLVICAVPAIMLFASMLKVPESPRWLISKGKNSEALRVLKQIR EDKRAEAECREIQEAVEKDTALEKASLKDFSTPWLRRLLWIGIGVAIVNQITGVNSIM YYGTQILKESGFGTKAALIANIGNGLISVIAVIFGIWLVGKVRRRPILLIGLAGTTTA LLLIAIFSIVLDGSMALPYVVLSLTVLFLAFMQGCVGPVTWLVIAEIFPQRLRGLGSG ISVFFLWILNFVIGFAFPILLSSVGLSFTFFIFVALGVLAIGFVYKFMPETKGRTLEE LEEHFRSRHDHNTPEQSVIEV*" gene 1896424..1897839 /gene="yncC" /locus_tag="BSU_17630" /old_locus_tag="BSU17630" downshifts 1897829 /Source="Nicolas_upshifts" /id="D955" /incds=0 /nref=13 /ntot=69 /MaxReadThrough="0.90595" /MaxDrop="4.35189" /score="15.579587" /energy="-8.6" /TU="NA" /idTUdmin="U1408" /TUdmin="-2" /isTUend="TRUE" downshifts complement(1897932) /Source="Nicolas_upshifts" /id="D956" /incds=0 /nref=13 /ntot=41 /MaxReadThrough="1.08869" /MaxDrop="5.39832" /score="24.3759796" /energy="-9.3" /TU="NA" /idTUdmin="U1409" /TUdmin="-3" /isTUend="TRUE" CDS complement(1897941..1899125) /gene="alrB" /locus_tag="BSU_17640" /old_locus_tag="BSU17640" /EC_number="5.1.1.1" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:10348844, 18399999" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10348844, 18399999; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="alanine racemase (minor activity)" /protein_id="NP_389646.1" /db_xref="EnsemblGenomes-Gn:BSU17640" /db_xref="EnsemblGenomes-Tr:CAB13648" /db_xref="GOA:P94494" /db_xref="InterPro:IPR000821" /db_xref="InterPro:IPR001608" /db_xref="InterPro:IPR009006" /db_xref="InterPro:IPR011079" /db_xref="InterPro:IPR020622" /db_xref="InterPro:IPR029066" /db_xref="PDB:5IRP" /db_xref="SubtiList:BG12267" /db_xref="UniProtKB/Swiss-Prot:P94494" /translation="MIKLCREVWIEVNLDAVKKNLRAIRRHIPHKSKIMAVVKANGYG HGSIEVARHALEHGASELAVASVEEGIVLRKAGITAPILVLGFTSLSCVKKSAAWNIT LSAFQVDWMKEANEILEKEASANRLAIHINVDTGMGRLGVRTKEELLEVVKALKASKF LRWTGIFTHFSTADEPDTTLTKLQHEKFISFLSFLKKQGIELPTVHMCNTAAAIAFPE FSADMIRLGIGLYGLYPSAYIKQLNLVKLEPALSLKARIAYVKTMRTEPRTVSYGATY IAEPNEVIATLPIGYADGYSRALSNRGFVLHRGKRVPVAGRVTMDMIMVSLGENGEGK QGDEVVIYGKQKGAEISVDEVAEMLNTINYEVVSTLSRRIPRFYIRDGEIFKVSTPVL YV*" gene complement(1897941..1899125) /gene="alrB" /locus_tag="BSU_17640" /old_locus_tag="BSU17640" S_feature complement(1899126..1899205) /Source="Nicolas_S_feature" /locus_tag="new_1899126_1899205_c" /HighExp="S4, S5, S3, S6, S7, B36, BT, S8, LoTm, T5.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigEF" /TUshortPSig="0.908" /TUlongSig="NA" /TUlongPSig="NA" /label="S638" promotor_-10 complement(1899198..1899216) /Source="Nicolas_upshift_promotors" /id="U1409" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.908091908091908" /psig="0.908091908091908" /xcortree=1129 /SigmaFactorBS="aggcaccttctcgtatcacatggatttgctgtTGAATGattt caaataaagttGAATAAAATAAGATCGAATcatccaacaattaacatttattcttgcg g" /listShort="S638, alrB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1899209) /Source="Nicolas_upshifts" /id="U1409" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.908091908091908" /psig="0.908091908091908" /xcortree=1129 /SigmaFactorBS="aggcaccttctcgtatcacatggatttgctgtTGAATGattt caaataaagttGAATAAAATAAGATCGAATcatccaacaattaacatttattcttgcg g" /listShort="S638, alrB" /GFF_Attribute="listLong" promotor_-35 complement(1899232..1899237) /Source="Nicolas_upshift_promotors" /id="U1409" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.908091908091908" /psig="0.908091908091908" /xcortree=1129 /SigmaFactorBS="aggcaccttctcgtatcacatggatttgctgtTGAATGattt caaataaagttGAATAAAATAAGATCGAATcatccaacaattaacatttattcttgcg g" /listShort="S638, alrB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1899517..1899524 /Source="Nicolas_upshift_promotors" /id="U1410" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.687312687312687" /psig="0.996003996003996" /xcortree=2322 /SigmaFactorBS="ataatcggttgaaaaggcagtcgattccttGTTCCATAaacc taacatcagaGTATATAATTATACTCGTATtcacaaaaatcgtttaagtaaggggtat a" /listShort="yncE, yncF, S640, ynzJ, S642, S643, thyA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1899539..1899558 /Source="Nicolas_upshift_promotors" /id="U1410" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.687312687312687" /psig="0.996003996003996" /xcortree=2322 /SigmaFactorBS="ataatcggttgaaaaggcagtcgattccttGTTCCATAaacc taacatcagaGTATATAATTATACTCGTATtcacaaaaatcgtttaagtaaggggtat a" /listShort="yncE, yncF, S640, ynzJ, S642, S643, thyA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1899547 /Source="Nicolas_upshifts" /id="U1410" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.687312687312687" /psig="0.996003996003996" /xcortree=2322 /SigmaFactorBS="ataatcggttgaaaaggcagtcgattccttGTTCCATAaacc taacatcagaGTATATAATTATACTCGTATtcacaaaaatcgtttaagtaaggggtat a" /listShort="yncE, yncF, S640, ynzJ, S642, S643, thyA" /GFF_Attribute="listLong" CDS 1899589..1900050 /gene="yncE" /locus_tag="BSU_17650" /old_locus_tag="BSU17650" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type h : extrachromosomal origin" /codon_start=1 /transl_table=11 /product="putative prophage protein" /protein_id="NP_389648.2" /db_xref="EnsemblGenomes-Gn:BSU17650" /db_xref="EnsemblGenomes-Tr:CAB13649" /db_xref="InterPro:IPR020216" /db_xref="SubtiList:BG12268" /db_xref="UniProtKB/Swiss-Prot:P94495" /translation="MNRGVSFQIPNEYGNFLWRILQPVEIANYRWQTSGESYFVVEGE LDDEELFHDYEIVEGAVFEQQLKTNQYYTIFVELKAFPYGKMVNQVNTYEEFADSDCE LVLLIADNSYVSIYCKNKNIIEKLYFNALQHDFEDVQFITDENDTRTSLTV*" gene 1899589..1900050 /gene="yncE" /locus_tag="BSU_17650" /old_locus_tag="BSU17650" CDS 1900080..1900514 /gene="dutA" /locus_tag="BSU_17660" /old_locus_tag="BSU17660" /EC_number="3.6.1.23" /function="16.8: Protect" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:11375514, 15939294, 16908222, 17169987, 21358047, 23897460" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11375514, 15939294, 16908222, 17169987, 21358047, 23897460; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="deoxyuridine 5'-triphosphate pyrophosphatase (phage origin)" /protein_id="NP_389649.1" /db_xref="EnsemblGenomes-Gn:BSU17660" /db_xref="EnsemblGenomes-Tr:CAB13650" /db_xref="GOA:O31801" /db_xref="InterPro:IPR029054" /db_xref="InterPro:IPR033704" /db_xref="InterPro:IPR036157" /db_xref="PDB:2XCD" /db_xref="PDB:2XCE" /db_xref="PDB:4AOO" /db_xref="PDB:4AOZ" /db_xref="PDB:4APZ" /db_xref="PDB:4B0H" /db_xref="SubtiList:BG13437" /db_xref="UniProtKB/Swiss-Prot:O31801" /translation="MTMQIKIKYLDETQTRISKIEQGDWIDLRAAEDVTIKKDEFKLV PLGVAMELPEGYEAHVVPRSSTYKNFGVIQTNSMGVIDESYKGDNDFWFFPAYALRDT EIKKGDRICQFRIMKKMPAVELVEVEHLGNEDRGGLGSTGTK*" gene 1900080..1900514 /gene="dutA" /locus_tag="BSU_17660" /old_locus_tag="BSU17660" S_feature complement(1900263..1900568) /Source="Nicolas_S_feature" /locus_tag="new_1900263_1900568_c" /HighExp="LoTm, S5, T5.0H, S8, T4.0H, S4, S7, T3.30H, Cold, T-4.40H" /AntisenseName="yncF" /AntisenseCor="-0.40042805081531202" /AntisenseRegPval="-11.1" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.997" /TUlongSig="NA" /TUlongPSig="NA" /label="S639" downshifts 1900361 /Source="Nicolas_upshifts" /id="D957" /incds=1 /nref=1 /ntot=1 /MaxReadThrough="4.18195" /MaxDrop="2.2821" /score="0.171090809" /energy="-9.3" /TU="U1410" /idTUdmin="U1408" /TUdmin=2530 /isTUend="FALSE" S_feature 1900515..1901611 /Source="Nicolas_S_feature" /locus_tag="new_1900515_1901611" /HighExp="S8, G150, G180, dia0, G135, UNK1, MG 15, Lbexp, Fru, S7" /AntisenseName="cotU" /AntisenseCor="-0.266961200384908" /AntisenseRegPval="-5" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.996" /TUlongSig="NA" /TUlongPSig="NA" /label="S640" S_feature complement(1900570..1900855) /Source="Nicolas_S_feature" /locus_tag="new_1900570_1900855_c" /HighExp="LoTm, dia5, dia15, T3.30H, T3.0H, T-4.40H, T4.0H, T5.0H, T-3.40H, Salt" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.25207000000000002" /TUshortSig="SigA" /TUshortPSig="0.997" /TUlongSig="NA" /TUlongPSig="NA" /label="S641" downshifts complement(1900613) /Source="Nicolas_upshifts" /id="D958" /incds=0 /nref=2 /ntot=95 /MaxReadThrough="4.29622" /MaxDrop="2.9464" /score="11.6697365" /energy="-9.7" /TU="U1411" /idTUdmin="U1411" /TUdmin="-308" /isTUend="FALSE" promotor_-10 complement(1900850..1900869) /Source="Nicolas_upshift_promotors" /id="U1411" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.96903096903097" /psig="0.997002997002997" /xcortree=3122 /SigmaFactorBS="tatttctttatagagatgcttgtttcatcGACAACtcaatcc taaaTGTGGTAAAATCGATAAAAAtgtaaaaactgtaaatataataaaaggagcatct t" /listShort="S641, S639" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1900855) /Source="Nicolas_upshifts" /id="U1411" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.96903096903097" /psig="0.997002997002997" /xcortree=3122 /SigmaFactorBS="tatttctttatagagatgcttgtttcatcGACAACtcaatcc taaaTGTGGTAAAATCGATAAAAAtgtaaaaactgtaaatataataaaaggagcatct t" /listShort="S641, S639" /GFF_Attribute="listLong" promotor_-35 complement(1900881..1900886) /Source="Nicolas_upshift_promotors" /id="U1411" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.96903096903097" /psig="0.997002997002997" /xcortree=3122 /SigmaFactorBS="tatttctttatagagatgcttgtttcatcGACAACtcaatcc taaaTGTGGTAAAATCGATAAAAAtgtaaaaactgtaaatataataaaaggagcatct t" /listShort="S641, S639" /GFF_Attribute="listLong" /label="promotor_-35" downshifts complement(1901117) /Source="Nicolas_upshifts" /id="D959" /incds=0 /nref=17 /ntot=130 /MaxReadThrough="2.07509" /MaxDrop="8.56023" /score="11.6697365" /energy="-9.7" /TU="NA" /idTUdmin="U1412" /TUdmin=1 /isTUend="TRUE" CDS complement(1901117..1901377) /gene="cotU" /locus_tag="BSU_17670" /old_locus_tag="BSU17670" /function="16.8: Protect" /function="16.13: Shape" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:12562816, 18065538, 20023017" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12562816, 18065538, 20023017; Product type f: factor" /codon_start=1 /transl_table=11 /product="spore coat protein" /protein_id="NP_389650.1" /db_xref="EnsemblGenomes-Gn:BSU17670" /db_xref="EnsemblGenomes-Tr:CAB13651" /db_xref="GOA:O31802" /db_xref="SubtiList:BG13471" /db_xref="UniProtKB/Swiss-Prot:O31802" /translation="MGYYKKYKEEYYTWKKTYYKKYYDNDKKHYDCDKYYDHDKKHYD YDKKYDDHDKKYYDDHDYHYEKKYYDDDDHYYDFVESYKKHH*" gene complement(1901117..1901377) /gene="cotU" /locus_tag="BSU_17670" /old_locus_tag="BSU17670" promotor_-10 complement(1901398..1901417) /Source="Nicolas_upshift_promotors" /id="U1412" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1427 /SigmaFactorBS="agcctctttttactattcttatttcatttGACCATACCAtat catttaaacTTCATAAATTAAATTCGAATaacataaaggaggaatttaattgggttat t" /listShort="cotU" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1901408) /Source="Nicolas_upshifts" /id="U1412" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1427 /SigmaFactorBS="agcctctttttactattcttatttcatttGACCATACCAtat catttaaacTTCATAAATTAAATTCGAATaacataaaggaggaatttaattgggttat t" /listShort="cotU" /GFF_Attribute="listLong" promotor_-35 complement(1901430..1901439) /Source="Nicolas_upshift_promotors" /id="U1412" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1427 /SigmaFactorBS="agcctctttttactattcttatttcatttGACCATACCAtat catttaaacTTCATAAATTAAATTCGAATaacataaaggaggaatttaattgggttat t" /listShort="cotU" /GFF_Attribute="listLong" /label="promotor_-35" CDS 1901612..1901737 /gene="ynzJ" /locus_tag="BSU_17678" /old_locus_tag="BSU17678" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /pseudo /codon_start=1 /transl_table=11 /product="hypothetical protein (putative phage origin)" /db_xref="PSEUDO:CAX52624.1" /translation="MNVMVKIQELYDVIFHTAFEGFRVRHQKQTAKPARNRSYKE*" gene 1901612..1901737 /gene="ynzJ" /locus_tag="BSU_17678" /old_locus_tag="BSU17678" /pseudo S_feature 1901738..1901854 /Source="Nicolas_S_feature" /locus_tag="new_1901738_1901854" /HighExp="G180, G135, G150, dia0, UNK1, S8, Lbexp, C90, MG 5, MG 150" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.996" /TUlongSig="NA" /TUlongPSig="NA" /label="S642" CDS 1901781..1901945 /locus_tag="BSU_17679" /old_locus_tag="BSU17679" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; Product type h: extrachromosomal origin" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein from phage origin" /protein_id="YP_009513957.1" /translation="MKLERIYFKESPIAHGQMTIDIEVKYNALNQKKLLEDLMCLDNF QFGIHKHLTI*" gene 1901781..1901945 /locus_tag="BSU_17679" /old_locus_tag="BSU17679" promotor_-35 1901829..1901838 /Source="Nicolas_upshift_promotors" /id="U1413" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.935064935064935" /psig="0.935064935064935" /xcortree=1261 /SigmaFactorBS="atttattttaaagaaagcccaattgcacatggaCAAATGACA AttgatattgaggtAAAATACAATGCATTAAATCagaaaaagctattggaggatttaa t" /listShort="S643, thyA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1901852..1901871 /Source="Nicolas_upshift_promotors" /id="U1413" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.935064935064935" /psig="0.935064935064935" /xcortree=1261 /SigmaFactorBS="atttattttaaagaaagcccaattgcacatggaCAAATGACA AttgatattgaggtAAAATACAATGCATTAAATCagaaaaagctattggaggatttaa t" /listShort="S643, thyA" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 1901856..1902166 /Source="Nicolas_S_feature" /locus_tag="new_1901856_1902166" /HighExp="S7, S6, S8, S5, BT, G/S, Pyr, G180, G150, G135" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.585202" /TUshortSig="SigK, SigA" /TUshortPSig="0.935, 0.996" /TUlongSig="NA" /TUlongPSig="NA" /label="S643" upshifts 1901856 /Source="Nicolas_upshifts" /id="U1413" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.935064935064935" /psig="0.935064935064935" /xcortree=1261 /SigmaFactorBS="atttattttaaagaaagcccaattgcacatggaCAAATGACA AttgatattgaggtAAAATACAATGCATTAAATCagaaaaagctattggaggatttaa t" /listShort="S643, thyA" /GFF_Attribute="listLong" promotor_-35 1902147..1902154 /Source="Nicolas_upshift_promotors" /id="U1414" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.916083916083916" /psig="0.99000999000999" /xcortree=1985 /SigmaFactorBS="gagtggaataagatcctcactttatctgcaagtgcttagTAT TTGCGataatattgcattCGTAATAAATTATGCTTAGCaactgaaaatgaaagaagga t" /listShort="thyA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1902168..1902187 /Source="Nicolas_upshift_promotors" /id="U1414" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.916083916083916" /psig="0.99000999000999" /xcortree=1985 /SigmaFactorBS="gagtggaataagatcctcactttatctgcaagtgcttagTAT TTGCGataatattgcattCGTAATAAATTATGCTTAGCaactgaaaatgaaagaagga t" /listShort="thyA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1902168 /Source="Nicolas_upshifts" /id="U1414" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.916083916083916" /psig="0.99000999000999" /xcortree=1985 /SigmaFactorBS="gagtggaataagatcctcactttatctgcaagtgcttagTAT TTGCGataatattgcattCGTAATAAATTATGCTTAGCaactgaaaatgaaagaagga t" /listShort="thyA" /GFF_Attribute="listLong" CDS 1902219..1903058 /gene="thyA" /locus_tag="BSU_17680" /old_locus_tag="BSU17680" /EC_number="2.1.1.45" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:416889, 418407, 9648749, 10091656, 10574451" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 416889, 418407, 9648749, 10091656, 10574451; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="thymidylate synthase A (phage origin)" /protein_id="NP_389651.1" /db_xref="EnsemblGenomes-Gn:BSU17680" /db_xref="EnsemblGenomes-Tr:CAB13652" /db_xref="GOA:P0CI79" /db_xref="InterPro:IPR000398" /db_xref="InterPro:IPR020940" /db_xref="InterPro:IPR023451" /db_xref="InterPro:IPR036926" /db_xref="PDB:1B02" /db_xref="PDB:1BKO" /db_xref="PDB:1BKP" /db_xref="PDB:1BSF" /db_xref="PDB:1BSP" /db_xref="SubtiList:BG11190" /db_xref="UniProtKB/Swiss-Prot:P0CI79" /translation="MTQFDKQYNSIIKDIINNGISDEEFDVRTKWDSDGTPAHTLSVI SKQMRFDNSEVPILTTKKVAWKTAIKELLWIWQLKSNDVNDLNMMGVHIWDQWKQEDG TIGHAYGFQLGKKNRSLNGEKVDQVDYLLHQLKNNPSSRRHITMLWNPDELDAMALTP CVYETQWYVKHGKLHLEVRARSNDMALGNPFNVFQYNVLQRMIAQVTGYELGEYIFNI GDCHVYTRHIDNLKIQMEREQFEAPELWINPEVKDFYDFTIDDFKLINYKHGDKLLFE VAV*" gene 1902219..1903058 /gene="thyA" /locus_tag="BSU_17680" /old_locus_tag="BSU17680" promotor_-10 complement(1902241..1902260) /Source="Nicolas_upshift_promotors" /id="U1415" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.651348651348651" /psig="0.982017982017982" /xcortree=3110 /SigmaFactorBS="ccatctgagtcccacttggttcttacatcaaactcttcgtct gaGATTccattattgataatATCCTTTATAATTGAATTGTattgtttatcgaattgcg t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1902262) /Source="Nicolas_upshifts" /id="U1415" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.651348651348651" /psig="0.982017982017982" /xcortree=3110 /SigmaFactorBS="ccatctgagtcccacttggttcttacatcaaactcttcgtct gaGATTccattattgataatATCCTTTATAATTGAATTGTattgtttatcgaattgcg t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(1902275..1902278) /Source="Nicolas_upshift_promotors" /id="U1415" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.651348651348651" /psig="0.982017982017982" /xcortree=3110 /SigmaFactorBS="ccatctgagtcccacttggttcttacatcaaactcttcgtct gaGATTccattattgataatATCCTTTATAATTGAATTGTattgtttatcgaattgcg t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 1903018 /Source="Nicolas_upshifts" /id="D960" /incds=0 /nref=6 /ntot=143 /MaxReadThrough="4.34299" /MaxDrop="3.3234" /score="1.39203037" /energy="-7.7" /TU="U1410,U1414" /idTUdmin="U1413" /TUdmin="-4" /isTUend="TRUE" downshifts complement(1903164) /Source="Nicolas_upshifts" /id="D961" /incds=0 /nref=6 /ntot=150 /MaxReadThrough="3.28185" /MaxDrop="3.73135" /score="3.23768043" /energy="-6.6" /TU="U1417" /idTUdmin="U1417" /TUdmin="-286" /isTUend="FALSE" S_feature complement(1903165..1903471) /Source="Nicolas_S_feature" /locus_tag="new_1903165_1903471_c" /HighExp="LBGstat, Lbstat, LoTm, B60, LPhT, M9-stat, T1.30H, B36, nit, T0.30H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.99924299999999999" /TUshortSig="SigA" /TUshortPSig="0.994" /TUlongSig="NA" /TUlongPSig="NA" /label="S644" CDS complement(1903181..1903468) /locus_tag="BSU_17689" /old_locus_tag="BSU17689" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="YP_009513958.1" /translation="MEHTGHSSFLQLFCLNLTLIRVEIGMKYEKTSLFGMILVIVALL ISIYFMCNTNALIPAGYDLAIHGIVISRTVMIAFTLYLVSKLGYFLLNKKD*" gene complement(1903181..1903468) /locus_tag="BSU_17689" /old_locus_tag="BSU17689" downshifts complement(1903208) /Source="Nicolas_upshifts" /id="D962" /incds=0 /nref=2 /ntot=85 /MaxReadThrough="3.82042" /MaxDrop="6.47995" /score="3.23768043" /energy="-6.6" /TU="U1417" /idTUdmin="U1418" /TUdmin=308 /isTUend="FALSE" promotor_-35 1903295..1903303 /Source="Nicolas_upshift_promotors" /id="U1416" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.98001998001998" /psig="0.98001998001998" /xcortree=1393 /SigmaFactorBS="tattacaattccatgaatagctagatcatatccagcAGGTAT CAAcgcatttgtattaCACATAAAATATATAGATATtagaagtgctacaataactaaa a" /listShort="S645" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1903317..1903336 /Source="Nicolas_upshift_promotors" /id="U1416" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.98001998001998" /psig="0.98001998001998" /xcortree=1393 /SigmaFactorBS="tattacaattccatgaatagctagatcatatccagcAGGTAT CAAcgcatttgtattaCACATAAAATATATAGATATtagaagtgctacaataactaaa a" /listShort="S645" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1903319 /Source="Nicolas_upshifts" /id="U1416" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.98001998001998" /psig="0.98001998001998" /xcortree=1393 /SigmaFactorBS="tattacaattccatgaatagctagatcatatccagcAGGTAT CAAcgcatttgtattaCACATAAAATATATAGATATtagaagtgctacaataactaaa a" /listShort="S645" /GFF_Attribute="listLong" S_feature 1903330..1903490 /Source="Nicolas_S_feature" /locus_tag="new_1903330_1903490" /HighExp="S8, S6, S7, BT, S5, S4, S3, Pyr, G/S, dia15" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigK" /TUshortPSig="0.98" /TUlongSig="NA" /TUlongPSig="NA" /label="S645" downshifts 1903462 /Source="Nicolas_upshifts" /id="D963" /incds=0 /nref=13 /ntot=53 /MaxReadThrough="1.26429" /MaxDrop="5.75919" /score="7.35184753" /energy="-11.1" /TU="NA" /idTUdmin="U1416" /TUdmin=0 /isTUend="TRUE" CDS complement(1903511..1904233) /gene="yncM" /locus_tag="BSU_17690" /old_locus_tag="BSU17690" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences" /codon_start=1 /transl_table=11 /product="conserved exported protein" /protein_id="NP_389652.2" /db_xref="EnsemblGenomes-Gn:BSU17690" /db_xref="EnsemblGenomes-Tr:CAB13653" /db_xref="GOA:O31803" /db_xref="InterPro:IPR029143" /db_xref="PDB:4HFS" /db_xref="SubtiList:BG13438" /db_xref="UniProtKB/Swiss-Prot:O31803" /translation="MVKKVLIAGAVGTAVLFGTLSSGIPGLPAADAQVAKAASELPNG IGGRVYLNSTGAVFTAKIVLPETVKNNDSVSTPYIYSGFRATSGTEADIGLQYSKQYN VWKPLMKVGSKNEETYIEGKDKFTYNKGFRPGSTVQMTIYKNLSGNTRMTLWGTNNDG YTGRIITEIQGTNIGTISKWKTLATAAVSYESQRDAIKATFSTSFNNITIDNKAVTPV VDTQDFAKVSVAGNNVTISVNK*" gene complement(1903511..1904233) /gene="yncM" /locus_tag="BSU_17690" /old_locus_tag="BSU17690" downshifts complement(1903516) /Source="Nicolas_upshifts" /id="D964" /incds=0 /nref=31 /ntot=133 /MaxReadThrough="5.62856" /MaxDrop="4.3658" /score="0.425084384" /energy="-11.1" /TU="U1417" /idTUdmin="U1418" /TUdmin=0 /isTUend="TRUE" misc_feature complement(1904258..1904277) /Source="Nicolas_upshift_promotors" /id="U1417" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.51048951048951" /psig="0.994005994005994" /xcortree=503 /SigmaFactorBS="ttcaaaatgaaatattttgtcgatttatatacgtaaatccag ttccaaaATAAGGTATAATAAATGGCGaaaccactatcaaaagggggaattttggtga a" /listShort="yncM, S644" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(1904266) /Source="Nicolas_upshifts" /id="U1417" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.51048951048951" /psig="0.994005994005994" /xcortree=503 /SigmaFactorBS="ttcaaaatgaaatattttgtcgatttatatacgtaaatccag ttccaaaATAAGGTATAATAAATGGCGaaaccactatcaaaagggggaattttggtga a" /listShort="yncM, S644" /GFF_Attribute="listLong" S_feature complement(1904268..1904392) /Source="Nicolas_S_feature" /locus_tag="new_1904268_1904392_c" /HighExp="H2O2, dia15, S8, G180, G150, Paraq, Oxctl, LBGstat, G135, LBGexp" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S646" CDS complement(1904393..1904749) /gene="ynzK" /locus_tag="BSU_17699" /old_locus_tag="BSU17699" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative membrane protein of unknown function (phage origin)" /protein_id="YP_003097731.1" /db_xref="EnsemblGenomes-Gn:BSU17699" /db_xref="EnsemblGenomes-Tr:CAX52625" /db_xref="GOA:C0H417" /db_xref="InterPro:IPR025621" /db_xref="UniProtKB/Swiss-Prot:C0H417" /translation="MYRNIVFYLILLCLFISVVMKSFEVIRTIANVICFIFVLLYFKD EMKTYSRKALAILSICFLFLVGICAFIILQGQTLMKRHLFFTGLETIAGILLIIVSLS ICTFILRKISNRLKRM*" gene complement(1904393..1904749) /gene="ynzK" /locus_tag="BSU_17699" /old_locus_tag="BSU17699" promotor_-10 complement(1904773..1904792) /Source="Nicolas_upshift_promotors" /id="U1418" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.957042957042957" /psig=1 /xcortree=1838 /SigmaFactorBS="acatagtttagttagttcataagtgagcgcattcaattTATT GcagttacaaagaaacTTTTATAAACTCTTTGAGGAtcctacataaaaggagaggttt t" /listShort="ynzK, S646, yncM" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1904790) /Source="Nicolas_upshifts" /id="U1418" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.957042957042957" /psig=1 /xcortree=1838 /SigmaFactorBS="acatagtttagttagttcataagtgagcgcattcaattTATT GcagttacaaagaaacTTTTATAAACTCTTTGAGGAtcctacataaaaggagaggttt t" /listShort="ynzK, S646, yncM" /GFF_Attribute="listLong" promotor_-35 complement(1904808..1904812) /Source="Nicolas_upshift_promotors" /id="U1418" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.957042957042957" /psig=1 /xcortree=1838 /SigmaFactorBS="acatagtttagttagttcataagtgagcgcattcaattTATT GcagttacaaagaaacTTTTATAAACTCTTTGAGGAtcctacataaaaggagaggttt t" /listShort="ynzK, S646, yncM" /GFF_Attribute="listLong" /label="promotor_-35" downshifts complement(1904989) /Source="Nicolas_upshifts" /id="D965" /incds=0 /nref=58 /ntot=194 /MaxReadThrough="0.902090000000001" /MaxDrop="9.00312" /score="34.0680178" /energy="-10.8" /TU="NA" /idTUdmin="U1419" /TUdmin="-21" /isTUend="TRUE" CDS complement(1904995..1905195) /gene="cotC" /locus_tag="BSU_17700" /old_locus_tag="BSU17700" /function="16.8: Protect" /function="16.13: Shape" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:10788508, 11741866, 14762008, 18065538, 2821284, 19933362, 20023017" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10788508, 11741866, 14762008, 18065538, 2821284, 19933362, 20023017; Product type s: structure" /codon_start=1 /transl_table=11 /product="spore coat protein (outer)" /protein_id="NP_389653.2" /db_xref="EnsemblGenomes-Gn:BSU17700" /db_xref="EnsemblGenomes-Tr:CAB13654" /db_xref="GOA:P07790" /db_xref="SubtiList:BG10492" /db_xref="UniProtKB/Swiss-Prot:P07790" /translation="MGYYKKYKEEYYTVKKTYYKKYYEYDKKDYDCDYDKKYDDYDKK YYDHDKKDYDYVVEYKKHKKHY*" gene complement(1904995..1905195) /gene="cotC" /locus_tag="BSU_17700" /old_locus_tag="BSU17700" downshifts 1905178 /Source="Nicolas_upshifts" /id="D966" /incds=0 /nref=14 /ntot=29 /MaxReadThrough="1.37504" /MaxDrop="5.08099" /score="-4.2739983" /energy="-8" /TU="NA" /idTUdmin="U1416" /TUdmin=1716 /isTUend="FALSE" promotor_-10 complement(1905217..1905236) /Source="Nicolas_upshift_promotors" /id="U1419" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp="0.974025974025974" /psig="0.974025974025974" /xcortree=1429 /SigmaFactorBS="acagcccttttttccttctatgattttaactGTCCAAGCCGc aaaatctactcGCCGTATAATAAAGCGTAGTaaaaataaaggaggagtatatatgggt t" /listShort="cotC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1905229) /Source="Nicolas_upshifts" /id="U1419" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp="0.974025974025974" /psig="0.974025974025974" /xcortree=1429 /SigmaFactorBS="acagcccttttttccttctatgattttaactGTCCAAGCCGc aaaatctactcGCCGTATAATAAAGCGTAGTaaaaataaaggaggagtatatatgggt t" /listShort="cotC" /GFF_Attribute="listLong" promotor_-35 complement(1905249..1905258) /Source="Nicolas_upshift_promotors" /id="U1419" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp="0.974025974025974" /psig="0.974025974025974" /xcortree=1429 /SigmaFactorBS="acagcccttttttccttctatgattttaactGTCCAAGCCGc aaaatctactcGCCGTATAATAAAGCGTAGTaaaaataaaggaggagtatatatgggt t" /listShort="cotC" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(1905370..1905558) /gene="tatAC" /locus_tag="BSU_17710" /old_locus_tag="BSU17710" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:10974125, 11007775, 26239117" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10974125, 11007775, 26239117; Product type t: transporter" /codon_start=1 /transl_table=11 /product="component of the twin-arginine pre-protein translocation pathway" /protein_id="NP_389654.1" /db_xref="EnsemblGenomes-Gn:BSU17710" /db_xref="EnsemblGenomes-Tr:CAB13655" /db_xref="GOA:O31804" /db_xref="InterPro:IPR003369" /db_xref="InterPro:IPR006312" /db_xref="SubtiList:BG13464" /db_xref="UniProtKB/Swiss-Prot:O31804" /translation="MELSFTKILVILFVGFLVFGPDKLPALGRAAGKALSEFKQATSG LTQDIRKNDSENKEDKQM*" gene complement(1905370..1905558) /gene="tatAC" /locus_tag="BSU_17710" /old_locus_tag="BSU17710" downshifts complement(1905386) /Source="Nicolas_upshifts" /id="D967" /incds=0 /nref=213 /ntot=254 /MaxReadThrough="3.38696" /MaxDrop="6.07983" /score="8.58114058" /energy="-11" /TU="U1420,U1421" /idTUdmin="U1420" /TUdmin="-374" /isTUend="FALSE" misc_feature complement(1905527..1905534) /Source="Nicolas_upshift_promotors" /id="U1420" /multdbtbs="-" /comp="M1" /sig="Sig-" /pcomp="0.405594405594406" /psig="0.405594405594406" /xcortree=1585 /SigmaFactorBS="aatttgtttaaaaggttgtacttcaatcagggggaaaaggat atggaattaagcttcacaaaaataCTCGTTATtttgtttgtgggttttttagtatttg g" /listShort="tatAC, cotC" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(1905540) /Source="Nicolas_upshifts" /id="U1420" /multdbtbs="-" /comp="M1" /sig="Sig-" /pcomp="0.405594405594406" /psig="0.405594405594406" /xcortree=1585 /SigmaFactorBS="aatttgtttaaaaggttgtacttcaatcagggggaaaaggat atggaattaagcttcacaaaaataCTCGTTATtttgtttgtgggttttttagtatttg g" /listShort="tatAC, cotC" /GFF_Attribute="listLong" promotor_-10 complement(1905587..1905606) /Source="Nicolas_upshift_promotors" /id="U1421" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.891108891108891" /psig="0.999000999001" /xcortree=488 /SigmaFactorBS="cgtctttgtgctggttttaaaatgttcaaaataaatgCATTC CCAtttgtactgctatcTCTTATAATTTGTTTAAAAGgttgtacttcaatcaggggga a" /listShort="tatAC, cotC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1905605) /Source="Nicolas_upshifts" /id="U1421" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.891108891108891" /psig="0.999000999001" /xcortree=488 /SigmaFactorBS="cgtctttgtgctggttttaaaatgttcaaaataaatgCATTC CCAtttgtactgctatcTCTTATAATTTGTTTAAAAGgttgtacttcaatcaggggga a" /listShort="tatAC, cotC" /GFF_Attribute="listLong" promotor_-35 complement(1905621..1905628) /Source="Nicolas_upshift_promotors" /id="U1421" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.891108891108891" /psig="0.999000999001" /xcortree=488 /SigmaFactorBS="cgtctttgtgctggttttaaaatgttcaaaataaatgCATTC CCAtttgtactgctatcTCTTATAATTTGTTTAAAAGgttgtacttcaatcaggggga a" /listShort="tatAC, cotC" /GFF_Attribute="listLong" /label="promotor_-35" CDS 1905637..1905774 /locus_tag="BSU_17715" /old_locus_tag="BSU17715" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_009513959.1" /translation="MNILKPAQRRIHKTAAAEYNVQCHLPKKQEAGWINYVALPEMIQ T*" gene 1905637..1905774 /locus_tag="BSU_17715" /old_locus_tag="BSU17715" promotor_-35 1905668..1905673 /Source="Nicolas_upshift_promotors" /id="U1422" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.983016983016983" /psig="0.983016983016983" /xcortree=1117 /SigmaFactorBS="ttaaaaccagcacaaagacggaTTCATAaaacggctgctgct GAATATAATGTCCAATGCCacctgcctaagaagcaggaggcaggctggatcaattatg t" /listShort="S647, yndA, S648, ynzB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1905688..1905706 /Source="Nicolas_upshift_promotors" /id="U1422" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.983016983016983" /psig="0.983016983016983" /xcortree=1117 /SigmaFactorBS="ttaaaaccagcacaaagacggaTTCATAaaacggctgctgct GAATATAATGTCCAATGCCacctgcctaagaagcaggaggcaggctggatcaattatg t" /listShort="S647, yndA, S648, ynzB" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 1905706..1905808 /Source="Nicolas_S_feature" /locus_tag="new_1905706_1905808" /HighExp="S3, S4, LoTm, BT, B36, S5, S7, S6, T5.0H, S8" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.35884500000000003" /TUshortSig="SigEF" /TUshortPSig="0.983" /TUlongSig="NA" /TUlongPSig="NA" /label="S647" upshifts 1905706 /Source="Nicolas_upshifts" /id="U1422" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.983016983016983" /psig="0.983016983016983" /xcortree=1117 /SigmaFactorBS="ttaaaaccagcacaaagacggaTTCATAaaacggctgctgct GAATATAATGTCCAATGCCacctgcctaagaagcaggaggcaggctggatcaattatg t" /listShort="S647, yndA, S648, ynzB" /GFF_Attribute="listLong" CDS 1905809..1906207 /gene="yndA" /locus_tag="BSU_17720" /old_locus_tag="BSU17720" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="putative exported protein of unknown function" /protein_id="NP_389655.1" /db_xref="EnsemblGenomes-Gn:BSU17720" /db_xref="EnsemblGenomes-Tr:CAB13656" /db_xref="SubtiList:BG13439" /db_xref="UniProtKB/Swiss-Prot:O31805" /translation="MRFTKVVGFLSVLGLAAVFPLTAQAEKAGTAGAGEWDKLGTYTY TYSSPTVYSTGGDFRVCLSGSTPFSVSLHLYEDDPGDNPDDYVGANYFSPGECHTFGS IGKFVDGSNNKAEFFVTDYSGKSKTVTFYD*" gene 1905809..1906207 /gene="yndA" /locus_tag="BSU_17720" /old_locus_tag="BSU17720" S_feature 1906208..1907012 /Source="Nicolas_S_feature" /locus_tag="new_1906208_1907012" /HighExp="LoTm, S3, BT, S4, B36, S6, S5, S7, S8, T5.0H" /AntisenseName="yndB" /AntisenseCor="-0.559713635360228" /AntisenseRegPval="-22.9" /CDS_PredictionProba="0.91098199999999996" /TUshortSig="SigEF" /TUshortPSig="0.983" /TUlongSig="NA" /TUlongPSig="NA" /label="S648" CDS complement(1906272..1906706) /gene="flvS" /locus_tag="BSU_17730" /old_locus_tag="BSU17730" /experiment="publication(s) with functional evidences, PMID:20818668, 28160315" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 20818668, 28160315; Product type r: regulator" /codon_start=1 /transl_table=11 /product="regulator of stress-related ATPase (flavonoid-sensing)" /protein_id="NP_389656.1" /db_xref="EnsemblGenomes-Gn:BSU17730" /db_xref="EnsemblGenomes-Tr:CAB13657" /db_xref="GOA:O31806" /db_xref="InterPro:IPR013538" /db_xref="InterPro:IPR023393" /db_xref="PDB:2KEW" /db_xref="PDB:2KTE" /db_xref="SubtiList:BG13440" /db_xref="UniProtKB/Swiss-Prot:O31806" /translation="MAQNNENALPDITKSITLEAPIQKVWETVSTSEGIAKWFMPNDF QLKEGQEFHLQSPFGPSPCKVLAVQAPTELSFEWDTEGWVVTFQLEDLGEKTGFTLIH SGWKEPNEVIGKANEKSSVVRGKMDGGWTGIVNERLRKAVEE*" gene complement(1906272..1906706) /gene="flvS" /locus_tag="BSU_17730" /old_locus_tag="BSU17730" downshifts complement(1906288) /Source="Nicolas_upshifts" /id="D968" /incds=0 /nref=213 /ntot=253 /MaxReadThrough="1.7995" /MaxDrop="6.63594" /score="29.1580701" /energy="-7" /TU="NA" /idTUdmin="U1423" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(1906736..1906755) /Source="Nicolas_upshift_promotors" /id="U1423" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.487512487512487" /psig="0.996003996003996" /xcortree=2282 /SigmaFactorBS="ctgttcaacagcagctctagcataaataatgcacgcTATGGA CAtgatcttattagtTATTATATGATTGAATTGAAaaaacatcatatgtcaagaggta a" /listShort="yndB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1906752) /Source="Nicolas_upshifts" /id="U1423" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.487512487512487" /psig="0.996003996003996" /xcortree=2282 /SigmaFactorBS="ctgttcaacagcagctctagcataaataatgcacgcTATGGA CAtgatcttattagtTATTATATGATTGAATTGAAaaaacatcatatgtcaagaggta a" /listShort="yndB" /GFF_Attribute="listLong" promotor_-35 complement(1906769..1906776) /Source="Nicolas_upshift_promotors" /id="U1423" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.487512487512487" /psig="0.996003996003996" /xcortree=2282 /SigmaFactorBS="ctgttcaacagcagctctagcataaataatgcacgcTATGGA CAtgatcttattagtTATTATATGATTGAATTGAAaaaacatcatatgtcaagaggta a" /listShort="yndB" /GFF_Attribute="listLong" /label="promotor_-35" CDS 1907013..1907201 /gene="ynzB" /locus_tag="BSU_17740" /old_locus_tag="BSU17740" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 23625846" /codon_start=1 /transl_table=11 /product="conserved protein involved in spore germination" /protein_id="NP_389657.2" /db_xref="EnsemblGenomes-Gn:BSU17740" /db_xref="EnsemblGenomes-Tr:CAB13658" /db_xref="SubtiList:BG13465" /db_xref="UniProtKB/Swiss-Prot:O31807" /translation="MLGKIKAAIDNSPGKPARILVSEKAFQQLEEEMRFVYVSKPKTI MGIPVEVSDQAESFKLEF*" gene 1907013..1907201 /gene="ynzB" /locus_tag="BSU_17740" /old_locus_tag="BSU17740" S_feature 1907202..1907287 /Source="Nicolas_S_feature" /locus_tag="new_1907202_1907287" /HighExp="LoTm, BT, S4, S6, S3, S8, S7, B36, S5, G/S" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="NA" /TUshortPSig="NA" /TUlongSig="NA" /TUlongPSig="NA" /label="S649" downshifts 1907246 /Source="Nicolas_upshifts" /id="D969" /incds=0 /nref=7 /ntot=89 /MaxReadThrough="2.20002" /MaxDrop="4.21414" /score="19.5879917" /energy="-11.9" /TU="NA" /idTUdmin="U1422" /TUdmin=0 /isTUend="TRUE" promotor_-35 1907316..1907322 /Source="Nicolas_upshift_promotors" /id="U1424" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=875 /SigmaFactorBS="tgatgaaatgttcatcatgcttttttattgagaaaaaagacg AACATAAaaaataggtatacGGGAAAAATAATcctattagagagaggggaactgacag a" /listShort="S650, yndD" /GFF_Attribute="listLong" /label="promotor_-35" S_feature 1907334..1907493 /Source="Nicolas_S_feature" /locus_tag="new_1907334_1907493" /HighExp="S8, S4, S6, S7, S5, S3, BT, ferm, LoTm, nit" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.95681300000000002" /TUshortSig="SigGF" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S650" upshifts 1907334 /Source="Nicolas_upshifts" /id="U1424" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=875 /SigmaFactorBS="tgatgaaatgttcatcatgcttttttattgagaaaaaagacg AACATAAaaaataggtatacGGGAAAAATAATcctattagagagaggggaactgacag a" /listShort="S650, yndD" /GFF_Attribute="listLong" promotor_-10 1907336..1907347 /Source="Nicolas_upshift_promotors" /id="U1424" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=875 /SigmaFactorBS="tgatgaaatgttcatcatgcttttttattgagaaaaaagacg AACATAAaaaataggtatacGGGAAAAATAATcctattagagagaggggaactgacag a" /listShort="S650, yndD" /GFF_Attribute="listLong" /label="promotor_-10" CDS 1907494..1909056 /gene="yndD" /locus_tag="BSU_17750" /old_locus_tag="BSU17750" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1c: Function from experimental evidences in the studied genus; PubMedId: 10762253, 27208128; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="spore germination receptor subunit" /protein_id="NP_389658.1" /db_xref="EnsemblGenomes-Gn:BSU17750" /db_xref="EnsemblGenomes-Tr:CAB13659" /db_xref="GOA:O31808" /db_xref="InterPro:IPR004995" /db_xref="SubtiList:BG13441" /db_xref="UniProtKB/Swiss-Prot:O31808" /translation="MMRWRNNQYKTQKQHKSDYSTAEKQDQDVLTGNIGYDLEHVKRK IGHNGDVHFRELEITQLHVKAALIFVEGLSDQDLINKGLSVLVMNQPNQVSDEISQSG KGILTSKQIKNQIVSIGDVIDSEKISDIVLNVFMGSTALLIDGIPQAFLLGTVKKQNR SIEEPLSEALVRGPRTGFTEELSTNTALLRQQGKNDQLTLQRFEVGTRLKKDLIIAYM NDIADPKVVEEVRKRVRGIEIDHLPESGYVEQLIEDNYLSPFPQVQSTERPDRVISGL MEGRVAILLDGTPFALIVPVTFSMMLQSPEDYYERWFPSSLIRLLRFIAAMITLFAPA LYISFISFHPGLIPTKLAISISGTRQGVPFPSLIEALFMEVAIEILREAGLRLPKPIG PAIGIVGGLIIGEAAVQAGIVSPIMVIVVALTAISSFAIPHYSTGIALRMLRFGAMFC AAVFGLFGVIMYYLLLSSHVVKLKSFGVPYASPAVPYHLKDWKDFVIRMPLLVMKRRP KMMNTDNTKRVK*" gene 1907494..1909056 /gene="yndD" /locus_tag="BSU_17750" /old_locus_tag="BSU17750" promotor_-10 complement(1907797..1907816) /Source="Nicolas_upshift_promotors" /id="U1425" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.952047952047952" /psig="0.982017982017982" /xcortree=2029 /SigmaFactorBS="ctgaatctatgacatcaccgattgatacGATTTGATttttta tctgtttcGAAGTTAAAATACCTTTGCCggattgagaaatttcatcgcttacctgatt a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1907806) /Source="Nicolas_upshifts" /id="U1425" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.952047952047952" /psig="0.982017982017982" /xcortree=2029 /SigmaFactorBS="ctgaatctatgacatcaccgattgatacGATTTGATttttta tctgtttcGAAGTTAAAATACCTTTGCCggattgagaaatttcatcgcttacctgatt a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(1907831..1907838) /Source="Nicolas_upshift_promotors" /id="U1425" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.952047952047952" /psig="0.982017982017982" /xcortree=2029 /SigmaFactorBS="ctgaatctatgacatcaccgattgatacGATTTGATttttta tctgtttcGAAGTTAAAATACCTTTGCCggattgagaaatttcatcgcttacctgatt a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" CDS 1909086..1910177 /gene="yndE" /locus_tag="BSU_17760" /old_locus_tag="BSU17760" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 10762253, 15849754, 16850406; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative spore germination integral inner membrane protein" /protein_id="NP_389659.1" /db_xref="EnsemblGenomes-Gn:BSU17760" /db_xref="EnsemblGenomes-Tr:CAB13660" /db_xref="GOA:O31809" /db_xref="InterPro:IPR002293" /db_xref="InterPro:IPR004761" /db_xref="SubtiList:BG13442" /db_xref="UniProtKB/Swiss-Prot:O31809" /translation="MFSPTSKITTAQATIIIINYMLAAGVLTLPRTVTEQTQSPDGWI SVLLGGVLAVIAGMIIAKLSQQYPKETFYEYSRHIVGKWLGHLISIVFITYFLALGAF EVRVMSEIVDFFLLEGTPSWAIIMTVLWIGLYSITQGLDPIARLFEMIFPITVIIFLT IALMSLGIFEINNLRPVLGDGIMPVLRGVKTTNLSFTCSEIMFILVAFMKKPKNAVKA VVIGTGVVTSFYMITMIMVIGALSVEGVVTRTWPGLDLMRSFEIPGLIFERFESFLLV IWIMQLFATFIITFYAASLGVSQVFKKKPLSCMFGLLPVIYILSCMPKNENDVFILGD TVSHIALYIFGALPILLLVISKWRKRGEK*" gene 1909086..1910177 /gene="yndE" /locus_tag="BSU_17760" /old_locus_tag="BSU17760" CDS 1910167..1911381 /gene="yndF" /locus_tag="BSU_17770" /old_locus_tag="BSU17770" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 10762253, 27208128; Product type lp: lipoprotein" /codon_start=1 /transl_table=11 /product="putative spore germination lipoprotein" /protein_id="NP_389660.1" /db_xref="EnsemblGenomes-Gn:BSU17770" /db_xref="EnsemblGenomes-Tr:CAB13661" /db_xref="GOA:O31810" /db_xref="InterPro:IPR008844" /db_xref="SubtiList:BG13443" /db_xref="UniProtKB/Swiss-Prot:O31810" /translation="MKSKLKRQLPAMVIVCLLMICVTGCWSSREIEDLGLTFAIAIDK GKETNTEKELKEEGGSYPKKDNITLTYQFVNEKAAGAGTSGGGGSGQGAQKAYINISE TGDSLQQIGSEVALRRDREVFSPHLKVVVMSEDVLHTFPIDEMLDQFFRDNEIRLSCL VLSAKGEARDALQLKENGEIPAFRLIGLGENEHKVSRILPPMTLAKLIGKLHSGSSFL LQNVVAANGAVKYSGAAVINGKSKKMIGTLNEYETEGITWIRGEGKGGVVKSHDKKSQ QTLAYDINKIKSRIQPIVKGKDISFHVDIESEGDLVENWNTKEALDTQFIDRLETTIE NEVKKIVGQVLKKIQHDYKADVAGFDESFRLTYPHLWKRVKNNWDDTFSKADITYSVN VTITHFGTVKTQ*" gene 1910167..1911381 /gene="yndF" /locus_tag="BSU_17770" /old_locus_tag="BSU17770" promotor_-35 1911459..1911466 /Source="Nicolas_upshift_promotors" /id="U1426" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.534465534465534" /psig="0.98001998001998" /xcortree=2419 /SigmaFactorBS="ttaggataaagatactttttttggagaGATATACActtttca aatcgacCAATATGCTAATATAGGAATtgcttgaaatagaagggagaaggggctgtga g" /listShort="yndG, yndH" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1911481..1911500 /Source="Nicolas_upshift_promotors" /id="U1426" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.534465534465534" /psig="0.98001998001998" /xcortree=2419 /SigmaFactorBS="ttaggataaagatactttttttggagaGATATACActtttca aatcgacCAATATGCTAATATAGGAATtgcttgaaatagaagggagaaggggctgtga g" /listShort="yndG, yndH" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1911492 /Source="Nicolas_upshifts" /id="U1426" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.534465534465534" /psig="0.98001998001998" /xcortree=2419 /SigmaFactorBS="ttaggataaagatactttttttggagaGATATACActtttca aatcgacCAATATGCTAATATAGGAATtgcttgaaatagaagggagaaggggctgtga g" /listShort="yndG, yndH" /GFF_Attribute="listLong" CDS 1911528..1912334 /gene="yndG" /locus_tag="BSU_17780" /old_locus_tag="BSU17780" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 11737947, 22333191, 27435445" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_389661.1" /db_xref="EnsemblGenomes-Gn:BSU17780" /db_xref="EnsemblGenomes-Tr:CAB13662" /db_xref="GOA:O31811" /db_xref="SubtiList:BG13444" /db_xref="UniProtKB/Swiss-Prot:O31811" /translation="MRQKPIYVEIEMKSDLDTLWEYTQNPSLHKEWDLRFSNITYLNS QPCEKQKFLYETRVGFGLKVSGTGETVGVFNKCSSERSSSLAFGSDHPLSLIRHGSGY WKYIQRENGKMTFLTQYQYKTAYGLLGRWIDRLLFRPLLGWATAWSFDALRLWVEQNK HPKRFIRSAIIYVFMCLFFSLFWFYQGFAGVKTSILTGTAEIGLAILWLLPLKRKWII HGVQACIFAGFACLGSEIFMWVLLSVFSAASGALSLQLPSARRTKRKRKK*" gene 1911528..1912334 /gene="yndG" /locus_tag="BSU_17780" /old_locus_tag="BSU17780" S_feature complement(1912142..1913240) /Source="Nicolas_S_feature" /locus_tag="new_1912142_1913240_c" /HighExp="S8, S6, S7, S5, T0.30H, T2.0H, GM 150, BT, T1.30H, T-4.40H" /AntisenseName="yndH" /AntisenseCor="-0.58089150558713998" /AntisenseRegPval="-24.9" /CDS_PredictionProba="NA" /TUshortSig="SigK" /TUshortPSig="0.989" /TUlongSig="NA" /TUlongPSig="NA" /label="S651" CDS 1912339..1912956 /gene="yndH" /locus_tag="BSU_17790" /old_locus_tag="BSU17790" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_389662.1" /db_xref="EnsemblGenomes-Gn:BSU17790" /db_xref="EnsemblGenomes-Tr:CAB13663" /db_xref="InterPro:IPR025311" /db_xref="SubtiList:BG13445" /db_xref="UniProtKB/Swiss-Prot:O31812" /translation="MSSIYEKSIINYHLLHPKLQKRYQLDGSHTFSGTGTMSEISGGS FLVRMLLKLGVFFRCFFSERGKDIPFTIQNRTCLLKSQHTGIEWNRTFFFKGKKRFFD ALMIYDEKENRILDFFGKPHLLLSVLTFEASLDGSLTITSGKQWLLICGKRIPLPKWL TGTSEVCETFDEKKNCFTIEVHVQNTILGTLFFYKGTFQEEERES*" gene 1912339..1912956 /gene="yndH" /locus_tag="BSU_17790" /old_locus_tag="BSU17790" CDS 1912953..1914593 /gene="yndJ" /locus_tag="BSU_17800" /old_locus_tag="BSU17800" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 12618455, 15849754, 16850406, 28615734; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative integral inner membrane protein" /protein_id="NP_389663.1" /db_xref="EnsemblGenomes-Gn:BSU17800" /db_xref="EnsemblGenomes-Tr:CAB13664" /db_xref="GOA:O31813" /db_xref="InterPro:IPR025450" /db_xref="SubtiList:BG13446" /db_xref="UniProtKB/Swiss-Prot:O31813" /translation="MKRNGIVSALCFIGFLAAEAPDISVAEALVLLSILFFVPGIFPF VFRQSPVRAAQFMENGLIQCYPVAAFFAVLALVTEVGGFALIWWMYTVFNALYAILRL WETKIHRIEETSVLFGLIYLAGGGFWFFAYAAHLQIMQFGPLIILLTAVHFHYSAFLI PIFNGLLGRTIRKHRMLYSWITWVILLSPLLIALGITYSKTLDVIAVSIYMAAIYLHA FLVFTAAFRTKTGTFLIRLSSAVLMITIAFSMIYSFGVFRQEVTLTINQMIWIHGFVN AFGVILPALIGWRIEDAKPFDADSVKTFSRIYGKRKIGEEFLANIQAENNARYSGLVD DMGSLRSKDFSPEKLAPLILSFYEQTIEYNIKAKVTWSTWFRPLAIIYEWFSRRIGQI HLSTNPDWYRMYSKIKGVHSKKDGRERVRAWIRTNEKNETIFTALYSVYRSNGEGYMN ISLPLPFSSMTGILKPYHHQEKLVLTSRRRKSRAGDEGIYLQTRAGTCPLPLSETFLI EAVHDNKLTAVHHMWLFGIKFLTVHYSITHINQPIERT*" gene 1912953..1914593 /gene="yndJ" /locus_tag="BSU_17800" /old_locus_tag="BSU17800" promotor_-10 complement(1913227..1913246) /Source="Nicolas_upshift_promotors" /id="U1427" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.98901098901099" /psig="0.98901098901099" /xcortree=1248 /SigmaFactorBS="caaaactgatgtctcttcgattctatgtatctTTGTTTCCCa aaggcggaggatCGCATACAATGCATTAAAAActgtgtacatccaccagataagtgcg a" /listShort="S651" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1913240) /Source="Nicolas_upshifts" /id="U1427" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.98901098901099" /psig="0.98901098901099" /xcortree=1248 /SigmaFactorBS="caaaactgatgtctcttcgattctatgtatctTTGTTTCCCa aaggcggaggatCGCATACAATGCATTAAAAActgtgtacatccaccagataagtgcg a" /listShort="S651" /GFF_Attribute="listLong" promotor_-35 complement(1913260..1913268) /Source="Nicolas_upshift_promotors" /id="U1427" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.98901098901099" /psig="0.98901098901099" /xcortree=1248 /SigmaFactorBS="caaaactgatgtctcttcgattctatgtatctTTGTTTCCCa aaggcggaggatCGCATACAATGCATTAAAAActgtgtacatccaccagataagtgcg a" /listShort="S651" /GFF_Attribute="listLong" /label="promotor_-35" S_feature complement(1914233..1914999) /Source="Nicolas_S_feature" /locus_tag="new_1914233_1914999_c" /HighExp="T2.0H, T1.30H, T2.30H, GM 150, T3.30H, T1.0H, C30, T3.0H, T4.0H, T0.30H" /AntisenseName="yndK" /AntisenseCor="-0.33555507319526101" /AntisenseRegPval="-7.8" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S652" CDS 1914630..1914995 /gene="yndK" /locus_tag="BSU_17810" /old_locus_tag="BSU17810" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type h : extrachromosomal origin" /codon_start=1 /transl_table=11 /product="putative phage/plasmid replication protein" /protein_id="NP_389664.1" /db_xref="EnsemblGenomes-Gn:BSU17810" /db_xref="EnsemblGenomes-Tr:CAB13665" /db_xref="GOA:O31814" /db_xref="SubtiList:BG13447" /db_xref="UniProtKB/Swiss-Prot:O31814" /translation="MNCFKILHRIKTGKEGFMVFYISLFLILWLAAGFAVGMKQVYVD QLFDKAVIERLEKEANDHGHADRMIKQRVLYIAAVTVSGFISVYYEMKTIPQRRNIRK IEKNIMKLNQAKKRRMKRK*" gene 1914630..1914995 /gene="yndK" /locus_tag="BSU_17810" /old_locus_tag="BSU17810" downshifts 1914972 /Source="Nicolas_upshifts" /id="D970" /incds=0 /nref=166 /ntot=243 /MaxReadThrough="2.62352" /MaxDrop="5.68917" /score="15.340233" /energy="-10.4" /TU="NA" /idTUdmin="U1426" /TUdmin=2226 /isTUend="FALSE" misc_RNA complement(1914992..1915272) /gene="surA" /locus_tag="BSU_misc_RNA_72" /product="small untranslated RNA controlled by sporulation" /experiment="publication(s) with functional evidences, PMID:16385044" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16385044; Product type n: RNA" gene complement(1914992..1915272) /gene="surA" /locus_tag="BSU_misc_RNA_72" S_feature complement(1915001..1915132) /Source="Nicolas_S_feature" /locus_tag="new_1915001_1915132_c" /HighExp="B60, T2.0H, T1.30H, T1.0H, T2.30H, M9-stat, LoTm, S5, T3.30H, T4.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="Sig-, SigA" /TUshortPSig="0.443, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S653" downshifts complement(1915044) /Source="Nicolas_upshifts" /id="D971" /incds=0 /nref=21 /ntot=129 /MaxReadThrough="4.91485" /MaxDrop="4.94426" /score="14.7738511" /energy="-10.4" /TU="U1429,U1431" /idTUdmin="U1429" /TUdmin="-22" /isTUend="TRUE" promotor_-35 1915092..1915101 /Source="Nicolas_upshift_promotors" /id="U1428" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp="0.934065934065934" /psig="0.934065934065934" /xcortree=1253 /SigmaFactorBS="agcttacttttcataaattcaaaaatgagaagAACAGCGCCC gggctaatggtatATAATATTGTGAATTTAACAaaaatttaacaaggaggacgagaga a" /listShort="S654, yndL, S657, fosB, S658, S659" /GFF_Attribute="listLong" /label="promotor_-35" misc_feature complement(1915114..1915123) /Source="Nicolas_upshift_promotors" /id="U1429" /multdbtbs="-" /comp="M3" /sig="Sig-" /pcomp="0.442557442557443" /psig="0.442557442557443" /xcortree=1043 /SigmaFactorBS="gaatgtaggtctctttgaggctttagcacgaattctctcgtc ctccttgttaaatttttgttaaattcaCAATATTATAtaccattagcccgggcgctgt t" /listShort="S653" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" promotor_-10 1915115..1915134 /Source="Nicolas_upshift_promotors" /id="U1428" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp="0.934065934065934" /psig="0.934065934065934" /xcortree=1253 /SigmaFactorBS="agcttacttttcataaattcaaaaatgagaagAACAGCGCCC gggctaatggtatATAATATTGTGAATTTAACAaaaatttaacaaggaggacgagaga a" /listShort="S654, yndL, S657, fosB, S658, S659" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1915120 /Source="Nicolas_upshifts" /id="U1428" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp="0.934065934065934" /psig="0.934065934065934" /xcortree=1253 /SigmaFactorBS="agcttacttttcataaattcaaaaatgagaagAACAGCGCCC gggctaatggtatATAATATTGTGAATTTAACAaaaatttaacaaggaggacgagaga a" /listShort="S654, yndL, S657, fosB, S658, S659" /GFF_Attribute="listLong" S_feature 1915122..1915220 /Source="Nicolas_S_feature" /locus_tag="new_1915122_1915220" /HighExp="S8, S6, S7, BT, S5, G/S, B36, C30, Pyr, UNK1" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.52117199999999997" /TUshortSig="SigK" /TUshortPSig="0.934" /TUlongSig="NA" /TUlongPSig="NA" /label="S654" upshifts complement(1915132) /Source="Nicolas_upshifts" /id="U1429" /multdbtbs="-" /comp="M3" /sig="Sig-" /pcomp="0.442557442557443" /psig="0.442557442557443" /xcortree=1043 /SigmaFactorBS="gaatgtaggtctctttgaggctttagcacgaattctctcgtc ctccttgttaaatttttgttaaattcaCAATATTATAtaccattagcccgggcgctgt t" /listShort="S653" /GFF_Attribute="listLong" S_feature complement(1915134..1915264) /Source="Nicolas_S_feature" /locus_tag="new_1915134_1915264_c" /HighExp="T2.0H, T1.30H, M9-stat, T2.30H, T1.0H, B60, LoTm, T4.0H, T3.30H, T0.30H" /AntisenseName="yndL" /AntisenseCor="0.22331158442510801" /AntisenseRegPval="-3.7" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S655" CDS 1915221..1915979 /gene="pghL" /locus_tag="BSU_17820" /old_locus_tag="BSU17820" /EC_number="3.4.19.-" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:26158264" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 26158264; Product type h: extrachromosomal origin" /codon_start=1 /transl_table=11 /product="phage gamma-polyglutamate hydrolase" /protein_id="NP_389665.1" /db_xref="EnsemblGenomes-Gn:BSU17820" /db_xref="EnsemblGenomes-Tr:CAB13666" /db_xref="GOA:O31815" /db_xref="InterPro:IPR008585" /db_xref="SubtiList:BG13448" /db_xref="UniProtKB/Swiss-Prot:O31815" /translation="MKPAKVSLLRRLLHSLKHVDCNIAKRFPSTIKIVKLLMIFMVFT PISSIYAEDVYQNFEELKNNEDPSDYGVVTKETGSPVLVLAIHGGGIEGGTSEVAREL SKEYSMYLFEGLKSAGNSVLHITSTHFDEPRALKMTGNHEYVISLHGYAEEDQQIEVG GTDRVRAADLVEKLQHAGFPAVLLNMDHPHAGVSPNNIANKSKTGLSIQIEMSTGFRK SLFGIFSLKSRAVTQNERFYEFTEVMFRFLKNSY*" gene 1915221..1915979 /gene="pghL" /locus_tag="BSU_17820" /old_locus_tag="BSU17820" promotor_-35 1915247 /Source="Nicolas_upshift_promotors" /id="U1430" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.308691308691309" /psig="0.211788211788212" /xcortree=1323 /SigmaFactorBS="gttgatttggacttagaggcggagtagatgaaaccggccaaa gtatccctgctCcGccgtttgctccattccttgaagcatgttgattgtaacatagcca a" /listShort="yndL, S657, fosB, S658, S659" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1915249 /Source="Nicolas_upshift_promotors" /id="U1430" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.308691308691309" /psig="0.211788211788212" /xcortree=1323 /SigmaFactorBS="gttgatttggacttagaggcggagtagatgaaaccggccaaa gtatccctgctCcGccgtttgctccattccttgaagcatgttgattgtaacatagcca a" /listShort="yndL, S657, fosB, S658, S659" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1915254 /Source="Nicolas_upshifts" /id="U1430" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.308691308691309" /psig="0.211788211788212" /xcortree=1323 /SigmaFactorBS="gttgatttggacttagaggcggagtagatgaaaccggccaaa gtatccctgctCcGccgtttgctccattccttgaagcatgttgattgtaacatagcca a" /listShort="yndL, S657, fosB, S658, S659" /GFF_Attribute="listLong" promotor_-10 complement(1915270..1915289) /Source="Nicolas_upshift_promotors" /id="U1431" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.867132867132867" /psig=1 /xcortree=481 /SigmaFactorBS="caataattttacaattttaaTAGTTGATggaaaacgtttggc TATGTTACAATCAACATGCTtcaaggaatggagcaaacggcggagcagggatactttg g" /listShort="S655, S653, S652" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1915271) /Source="Nicolas_upshifts" /id="U1431" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.867132867132867" /psig=1 /xcortree=481 /SigmaFactorBS="caataattttacaattttaaTAGTTGATggaaaacgtttggc TATGTTACAATCAACATGCTtcaaggaatggagcaaacggcggagcagggatactttg g" /listShort="S655, S653, S652" /GFF_Attribute="listLong" promotor_-35 complement(1915304..1915311) /Source="Nicolas_upshift_promotors" /id="U1431" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.867132867132867" /psig=1 /xcortree=481 /SigmaFactorBS="caataattttacaattttaaTAGTTGATggaaaacgtttggc TATGTTACAATCAACATGCTtcaaggaatggagcaaacggcggagcagggatactttg g" /listShort="S655, S653, S652" /GFF_Attribute="listLong" /label="promotor_-35" S_feature complement(1915794..1916005) /Source="Nicolas_S_feature" /locus_tag="new_1915794_1916005_c" /HighExp="S8, S5, S7, S6, S4, ferm, nit, BT, Pyr, G/S" /AntisenseName="yndL" /AntisenseCor="0.82198535504067005" /AntisenseRegPval="-66.5" /CDS_PredictionProba="NA" /TUshortSig="SigGF" /TUshortPSig="0.515" /TUlongSig="NA" /TUlongPSig="NA" /label="S656" downshifts 1915958 /Source="Nicolas_upshifts" /id="D972" /incds=0 /nref=3 /ntot=23 /MaxReadThrough="4.17889" /MaxDrop="5.0493" /score="15.340233" /energy="-10.4" /TU="U1428,U1430" /idTUdmin="U1428" /TUdmin="-1540" /isTUend="FALSE" S_feature 1916003..1916622 /Source="Nicolas_S_feature" /locus_tag="new_1916003_1916622" /HighExp="S8, S6, S7, S5, C30, BT, G135, LBGstat, GM 150, M/G" /AntisenseName="yndM" /AntisenseCor="0.75549671487088998" /AntisenseRegPval="-50.2" /CDS_PredictionProba="NA" /TUshortSig="Sig-, SigK" /TUshortPSig="0.212, 0.934" /TUlongSig="NA" /TUlongPSig="NA" /label="S657" CDS complement(1916006..1916545) /gene="yndM" /locus_tag="BSU_17830" /old_locus_tag="BSU17830" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative integral inner membrane protein" /protein_id="NP_389666.1" /db_xref="EnsemblGenomes-Gn:BSU17830" /db_xref="EnsemblGenomes-Tr:CAB13667" /db_xref="GOA:O31816" /db_xref="InterPro:IPR019649" /db_xref="SubtiList:BG13449" /db_xref="UniProtKB/Swiss-Prot:O31816" /translation="MTIMNGFELHYLSFVYAQEFSSKNNNLGGQMKHIIALASKIAFT LALLYVILDRVYHASFLSVMFIALFLGFVSYLSGDMLVLPRTNNITASLADFGLSFVI LWVFVLTQTRNDFSPFGAALLSAACLTVFEYFFHRYLLKNVLDENFRNELSARDNTLQ YQTEAADELFPETKEKHKE*" gene complement(1916006..1916545) /gene="yndM" /locus_tag="BSU_17830" /old_locus_tag="BSU17830" promotor_-10 complement(1916546..1916560) /Source="Nicolas_upshift_promotors" /id="U1432" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.515484515484515" /psig="0.515484515484515" /xcortree=865 /SigmaFactorBS="taagaaagtttcatacagctgaaaaaaataccAGTGTAAaca aaaacggactGTTTAAAATAGTAACatgaccattatgaatggttttgaattgcattat t" /listShort="yndM, S656" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1916552) /Source="Nicolas_upshifts" /id="U1432" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.515484515484515" /psig="0.515484515484515" /xcortree=865 /SigmaFactorBS="taagaaagtttcatacagctgaaaaaaataccAGTGTAAaca aaaacggactGTTTAAAATAGTAACatgaccattatgaatggttttgaattgcattat t" /listShort="yndM, S656" /GFF_Attribute="listLong" promotor_-35 complement(1916574..1916580) /Source="Nicolas_upshift_promotors" /id="U1432" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.515484515484515" /psig="0.515484515484515" /xcortree=865 /SigmaFactorBS="taagaaagtttcatacagctgaaaaaaataccAGTGTAAaca aaaacggactGTTTAAAATAGTAACatgaccattatgaatggttttgaattgcattat t" /listShort="yndM, S656" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1916600..1916609 /Source="Nicolas_upshift_promotors" /id="U1433" /multdbtbs="SigW" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1668 /SigmaFactorBS="ccgtttttgtttacactggtatttttttcagctgtaTGAAAC TTTCttatgaaaaaagTCGTATATGTGGATGAtcagctttcaaggggggaatgatttg t" /listShort="fosB, S658, S659" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1916622..1916637 /Source="Nicolas_upshift_promotors" /id="U1433" /multdbtbs="SigW" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1668 /SigmaFactorBS="ccgtttttgtttacactggtatttttttcagctgtaTGAAAC TTTCttatgaaaaaagTCGTATATGTGGATGAtcagctttcaaggggggaatgatttg t" /listShort="fosB, S658, S659" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1916624 /Source="Nicolas_upshifts" /id="U1433" /multdbtbs="SigW" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1668 /SigmaFactorBS="ccgtttttgtttacactggtatttttttcagctgtaTGAAAC TTTCttatgaaaaaagTCGTATATGTGGATGAtcagctttcaaggggggaatgatttg t" /listShort="fosB, S658, S659" /GFF_Attribute="listLong" CDS 1916663..1917097 /gene="fosB" /locus_tag="BSU_17840" /old_locus_tag="BSU17840" /EC_number="2.5.1.-" /function="16.8: Protect" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:11244082, 16399398, 19763274, 23256780" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11244082, 16399398, 19763274, 23256780; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="magnesium-dependent bacillithiol-transferase" /protein_id="NP_389667.1" /db_xref="EnsemblGenomes-Gn:BSU17840" /db_xref="EnsemblGenomes-Tr:CAB13668" /db_xref="GOA:O31817" /db_xref="InterPro:IPR004360" /db_xref="InterPro:IPR022858" /db_xref="InterPro:IPR029068" /db_xref="SubtiList:BG13450" /db_xref="UniProtKB/Swiss-Prot:O31817" /translation="MEIKGINHLLFSVSHLDTSIDFYQKVFGAKLLVKGRTTAYFDMN GIWLALNEEPDIPRNDIKLSYTHIAFTIEDHEFEEMSAKLKRLHVNILPGRERDERDR KSIYFTDPDGHKFEFHTGTLQDRLRYYKQEKTHMHFYDETAF*" gene 1916663..1917097 /gene="fosB" /locus_tag="BSU_17840" /old_locus_tag="BSU17840" CDS 1916955..1917302 /gene="yzzP" /locus_tag="BSU_17845" /old_locus_tag="BSU17845" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 27144405" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="YP_009513960.1" /translation="MNAIENQFILPTLTATNLNFIPEPFKTGFDITNKKKRICTFMMK RPFDSTTIFHIRLNLKKGVGGDFMFGEGFYPTCSTMPYLLNCTSDWVKVKLKYTLHYI LYEESELFYQMLN*" gene 1916955..1917302 /gene="yzzP" /locus_tag="BSU_17845" /old_locus_tag="BSU17845" S_feature 1917098..1917430 /Source="Nicolas_S_feature" /locus_tag="new_1917098_1917430" /HighExp="T0.30H, T1.0H, T1.30H, T2.0H, T-0.40H, T0.0H, T-1.10H, T2.30H, Salt, T-1.40H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.66836499999999999" /TUshortSig="SigWXY, Sig-, SigK" /TUshortPSig="1, 0.212, 0.934" /TUlongSig="NA" /TUlongPSig="NA" /label="S658" promotor_-35 1917389..1917398 /Source="Nicolas_upshift_promotors" /id="U1434" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp="0.99000999000999" /psig="0.99000999000999" /xcortree=425 /SigmaFactorBS="ttccacgacctaaaaaaTGAAACGTTTttaagaagatgGCGT CTAATATTCTAAatgttcatattttgataaaagtttcctaaaggaaagaaaatttctt g" /listShort="S659" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1917410..1917425 /Source="Nicolas_upshift_promotors" /id="U1434" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp="0.99000999000999" /psig="0.99000999000999" /xcortree=425 /SigmaFactorBS="ttccacgacctaaaaaaTGAAACGTTTttaagaagatgGCGT CTAATATTCTAAatgttcatattttgataaaagtttcctaaaggaaagaaaatttctt g" /listShort="S659" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 1917432..1917610 /Source="Nicolas_S_feature" /locus_tag="new_1917432_1917610" /HighExp="T0.30H, T1.0H, T1.30H, T2.0H, T-0.40H, T-1.10H, T0.0H, T2.30H, T3.0H, BC" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigWXY, SigWXY, Sig-, SigK" /TUshortPSig="0.99, 1, 0.212, 0.934" /TUlongSig="NA" /TUlongPSig="NA" /label="S659" upshifts 1917432 /Source="Nicolas_upshifts" /id="U1434" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp="0.99000999000999" /psig="0.99000999000999" /xcortree=425 /SigmaFactorBS="ttccacgacctaaaaaaTGAAACGTTTttaagaagatgGCGT CTAATATTCTAAatgttcatattttgataaaagtttcctaaaggaaagaaaatttctt g" /listShort="S659" /GFF_Attribute="listLong" misc_RNA 1917501..1917580 /gene="ncrF" /locus_tag="BSU_misc_RNA_73" /product="putative conserved small untranslated RNA" /experiment="publication(s) with functional evidences, PMID:20525796" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 20525796; Product type n: RNA" gene 1917501..1917580 /gene="ncrF" /locus_tag="BSU_misc_RNA_73" downshifts 1917567 /Source="Nicolas_upshifts" /id="D973" /incds=0 /nref=16 /ntot=188 /MaxReadThrough="2.99425" /MaxDrop="4.30173" /score="-1.31226475" /energy="-14.3" /TU="U1433" /idTUdmin="U1434" /TUdmin=3 /isTUend="TRUE" CDS complement(1917639..1918256) /gene="lexA" /locus_tag="BSU_17850" /old_locus_tag="BSU17850" /function="16.8: Protect" /function="16.3: Control" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:14652736, 16267290, 16269821, 16855250, 17042786, 19684115, 24285298" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 14652736, 16267290, 16269821, 16855250, 17042786, 19684115, 24285298; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional repressor of the SOS regulon" /protein_id="NP_389668.1" /db_xref="EnsemblGenomes-Gn:BSU17850" /db_xref="EnsemblGenomes-Tr:CAB13669" /db_xref="GOA:P31080" /db_xref="InterPro:IPR006197" /db_xref="InterPro:IPR006199" /db_xref="InterPro:IPR006200" /db_xref="InterPro:IPR011991" /db_xref="InterPro:IPR015927" /db_xref="InterPro:IPR036286" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG10678" /db_xref="UniProtKB/Swiss-Prot:P31080" /translation="MTKLSKRQLDILRFIKAEVKSKGYPPSVREIGEAVGLASSSTVH GHLARLETKGLIRRDPTKPRAIEILDEEVDIPQSQVVNVPVIGKVTAGSPITAVENIE EYFPLPDRMVPPDEHVFMLEIMGDSMIDAGILDKDYVIVKQQNTANNGEIVVAMTEDD EATVKRFYKEDTHIRLQPENPTMEPIILQNVSILGKVIGVFRTVH*" gene complement(1917639..1918256) /gene="lexA" /locus_tag="BSU_17850" /old_locus_tag="BSU17850" downshifts complement(1917640) /Source="Nicolas_upshifts" /id="D974" /incds=0 /nref=186 /ntot=254 /MaxReadThrough="2.74616" /MaxDrop="7.90985" /score="8.16083322" /energy="-16.3" /TU="U1435" /idTUdmin="U1435" /TUdmin="-44" /isTUend="FALSE" promotor_-10 complement(1918280..1918299) /Source="Nicolas_upshift_promotors" /id="U1435" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.659340659340659" /psig=1 /xcortree=2083 /SigmaFactorBS="tatacgaacaaacgtttctgtcaattgttttttcgaacctaT GTTTGTActgtaaggaaaatCATGCTATAATCTTCTTAAAatcgacgttttgaggtgc g" /listShort="lexA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1918301) /Source="Nicolas_upshifts" /id="U1435" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.659340659340659" /psig=1 /xcortree=2083 /SigmaFactorBS="tatacgaacaaacgtttctgtcaattgttttttcgaacctaT GTTTGTActgtaaggaaaatCATGCTATAATCTTCTTAAAatcgacgttttgaggtgc g" /listShort="lexA" /GFF_Attribute="listLong" promotor_-35 complement(1918313..1918320) /Source="Nicolas_upshift_promotors" /id="U1435" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.659340659340659" /psig=1 /xcortree=2083 /SigmaFactorBS="tatacgaacaaacgtttctgtcaattgttttttcgaacctaT GTTTGTActgtaaggaaaatCATGCTATAATCTTCTTAAAatcgacgttttgaggtgc g" /listShort="lexA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1918336..1918343 /Source="Nicolas_upshift_promotors" /id="U1436" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.957042957042957" /psig=1 /xcortree=1508 /SigmaFactorBS="gcatgattttccttacagtacaaacataggttcgaaaaaacA ATTGACAgaaacgtttgttcGTATATACTGAAATTATAAAaatgcgaacaaacattcc t" /listShort="yneA, yneB, ynzC, S660, tkt" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 1918355 /Source="Nicolas_upshifts" /id="U1436" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.957042957042957" /psig=1 /xcortree=1508 /SigmaFactorBS="gcatgattttccttacagtacaaacataggttcgaaaaaacA ATTGACAgaaacgtttgttcGTATATACTGAAATTATAAAaatgcgaacaaacattcc t" /listShort="yneA, yneB, ynzC, S660, tkt" /GFF_Attribute="listLong" promotor_-10 1918357..1918376 /Source="Nicolas_upshift_promotors" /id="U1436" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.957042957042957" /psig=1 /xcortree=1508 /SigmaFactorBS="gcatgattttccttacagtacaaacataggttcgaaaaaacA ATTGACAgaaacgtttgttcGTATATACTGAAATTATAAAaatgcgaacaaacattcc t" /listShort="yneA, yneB, ynzC, S660, tkt" /GFF_Attribute="listLong" /label="promotor_-10" CDS 1918406..1918723 /gene="dinK" /locus_tag="BSU_17860" /old_locus_tag="BSU17860" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:12581363, 16267290, 16549676, 20400548, 20807205, 23728628" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12581363, 16267290, 16549676, 20400548, 20807205, 23728628; Product type cp : cell process" /codon_start=1 /transl_table=11 /product="cell division inhibitor" /protein_id="NP_389669.1" /db_xref="EnsemblGenomes-Gn:BSU17860" /db_xref="EnsemblGenomes-Tr:CAB13670" /db_xref="GOA:Q45056" /db_xref="InterPro:IPR018392" /db_xref="InterPro:IPR022887" /db_xref="InterPro:IPR036779" /db_xref="SubtiList:BG11820" /db_xref="UniProtKB/Swiss-Prot:Q45056" /translation="MIMSKESIIFVGLFTVILSAVILMLSYTSSGQELNQYVKIEVQQ GDTLWSIADQVADTKKINKNDFIEWVADKNQLQTSDIQPGDELVIPLKKKHQDAYELA TVR*" gene 1918406..1918723 /gene="dinK" /locus_tag="BSU_17860" /old_locus_tag="BSU17860" promotor_-10 complement(1918423..1918441) /Source="Nicolas_upshift_promotors" /id="U1437" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=2844 /SigmaFactorBS="atatgacagcataaggataaccgcGCTCAAAAtcactgtaaa cagACCGACAAAAATAATAGATtctttactcatgatcataacctccaacaggaatgtt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1918426) /Source="Nicolas_upshifts" /id="U1437" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=2844 /SigmaFactorBS="atatgacagcataaggataaccgcGCTCAAAAtcactgtaaa cagACCGACAAAAATAATAGATtctttactcatgatcataacctccaacaggaatgtt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(1918455..1918462) /Source="Nicolas_upshift_promotors" /id="U1437" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=2844 /SigmaFactorBS="atatgacagcataaggataaccgcGCTCAAAAtcactgtaaa cagACCGACAAAAATAATAGATtctttactcatgatcataacctccaacaggaatgtt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" CDS 1918742..1919395 /gene="dinL" /locus_tag="BSU_17870" /old_locus_tag="BSU17870" /function="16.9: Replicate" /function="16.13: Shape" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 12581363, 16267290, 17020588, 19060143, 22933559; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative site-specific recombinase, resolvase" /protein_id="NP_389670.1" /db_xref="EnsemblGenomes-Gn:BSU17870" /db_xref="EnsemblGenomes-Tr:CAB13671" /db_xref="GOA:Q45057" /db_xref="InterPro:IPR006119" /db_xref="InterPro:IPR036162" /db_xref="SubtiList:BG11821" /db_xref="UniProtKB/Swiss-Prot:Q45057" /translation="MKALIYARVSTNKEQQETSLKRQEEELTAIAAENGMEVVKVISE KASGYEMDRDGVFELLDEIKNADIDVILVQDETRLGRGNAKIALLHCIYREGVKVYTT AHRGELELSEADSMVLEIVSIVEEYQRKIHNMKIRRGMKRAVKNGFKPQKNLKNQHGN SGKEKIEVPISEIVRLRANKLTFAEIAATLRGFGYDVSKATVHRRFQEYIENEETAE* " gene 1918742..1919395 /gene="dinL" /locus_tag="BSU_17870" /old_locus_tag="BSU17870" promotor_-35 1919398..1919405 /Source="Nicolas_upshift_promotors" /id="U1438" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.965034965034965" /psig=1 /xcortree=2084 /SigmaFactorBS="gagaatgaagagactgcagagtgaatCAGTTGTAaaactttt tttgaTCTAGTACTATATAGACAAAatgcaataaaggagtttaacatgatttcaaacg c" /listShort="ynzC, S660, tkt" /listLong="yneE, yneF" /label="promotor_-35" promotor_-10 1919419..1919438 /Source="Nicolas_upshift_promotors" /id="U1438" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.965034965034965" /psig=1 /xcortree=2084 /SigmaFactorBS="gagaatgaagagactgcagagtgaatCAGTTGTAaaactttt tttgaTCTAGTACTATATAGACAAAatgcaataaaggagtttaacatgatttcaaacg c" /listShort="ynzC, S660, tkt" /listLong="yneE, yneF" /label="promotor_-10" upshifts 1919432 /Source="Nicolas_upshifts" /id="U1438" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.965034965034965" /psig=1 /xcortree=2084 /SigmaFactorBS="gagaatgaagagactgcagagtgaatCAGTTGTAaaactttt tttgaTCTAGTACTATATAGACAAAatgcaataaaggagtttaacatgatttcaaacg c" /listShort="ynzC, S660, tkt" /listLong="yneE, yneF" CDS 1919459..1919692 /gene="ynzC" /locus_tag="BSU_17880" /old_locus_tag="BSU17880" /function="16.8: Protect" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 12581363, 16267290, 18431750,19306341, 22333191, 22933559, 23099262" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_389671.1" /db_xref="EnsemblGenomes-Gn:BSU17880" /db_xref="EnsemblGenomes-Tr:CAB13672" /db_xref="GOA:O31818" /db_xref="InterPro:IPR009242" /db_xref="PDB:2HEP" /db_xref="PDB:2JVD" /db_xref="PDB:3BHP" /db_xref="SubtiList:BG13466" /db_xref="UniProtKB/Swiss-Prot:O31818" /translation="MISNAKIARINELAAKAKAGVITEEEKAEQQKLRQEYLKGFRSS MKNTLKSVKIIDPEGNDVTPEKLKREQRNNKLH*" gene 1919459..1919692 /gene="ynzC" /locus_tag="BSU_17880" /old_locus_tag="BSU17880" S_feature 1919693..1919828 /Source="Nicolas_S_feature" /locus_tag="new_1919693_1919828" /HighExp="M40t90, M40t45, dia15, C90, Etha, H2O2, T5.0H, Salt, dia5, HiOs" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="1, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S660" promotor_-35 1919796..1919803 /Source="Nicolas_upshift_promotors" /id="U1439" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.976023976023976" /psig="0.999000999001" /xcortree=2357 /SigmaFactorBS="aagtttctctcaaatttaagctgaaaCAGTTGAGaaaaagtc gtcagACATTTATGATGTAAGGGTAcaacacataaggaaggggatttttatggataca a" /listShort="tkt, yneE" /listLong="yneF" /label="promotor_-35" promotor_-10 1919817..1919836 /Source="Nicolas_upshift_promotors" /id="U1439" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.976023976023976" /psig="0.999000999001" /xcortree=2357 /SigmaFactorBS="aagtttctctcaaatttaagctgaaaCAGTTGAGaaaaagtc gtcagACATTTATGATGTAAGGGTAcaacacataaggaaggggatttttatggataca a" /listShort="tkt, yneE" /listLong="yneF" /label="promotor_-10" upshifts 1919830 /Source="Nicolas_upshifts" /id="U1439" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.976023976023976" /psig="0.999000999001" /xcortree=2357 /SigmaFactorBS="aagtttctctcaaatttaagctgaaaCAGTTGAGaaaaagtc gtcagACATTTATGATGTAAGGGTAcaacacataaggaaggggatttttatggataca a" /listShort="tkt, yneE" /listLong="yneF" CDS 1919861..1921864 /gene="tktA" /locus_tag="BSU_17890" /old_locus_tag="BSU17890" /EC_number="2.2.1.1" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:9696621, 12682299, 12882400, 27739585" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9696621, 12682299, 12882400, 27739585; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="transketolase" /protein_id="NP_389672.1" /db_xref="EnsemblGenomes-Gn:BSU17890" /db_xref="EnsemblGenomes-Tr:CAB13673" /db_xref="GOA:P45694" /db_xref="InterPro:IPR005474" /db_xref="InterPro:IPR005475" /db_xref="InterPro:IPR005478" /db_xref="InterPro:IPR009014" /db_xref="InterPro:IPR020826" /db_xref="InterPro:IPR029061" /db_xref="InterPro:IPR033247" /db_xref="InterPro:IPR033248" /db_xref="SubtiList:BG11247" /db_xref="UniProtKB/Swiss-Prot:P45694" /translation="MDTIEKKSVATIRTLSIDAIEKANSGHPGMPMGAAPMAYTLWTK FMNVSPANPGWFNRDRFVLSAGHGSALLYSMLHLSGFDLSIEDLKGFRQWGSKTPGHP EFGHTAGVDATTGPLGQGIAMAVGMAIAERHLAETYNRDSFNVVDHYTYSICGDGDLM EGISSEAASLAGHLQLGRLIVLYDSNDISLDGDLDRSFSENVKQRFEAMNWEVLYVED GNNIEELTAAIEKARQNEKKPTLIEVKTTIGFGSPNRAGTSGVHGAPLGKEESKLTKE AYAWTYEEDFYVPSEVYEHFAVAVKESGEKKEQEWNAQFAKYKEVYPELAEQLELAIK GELPKDWDQEVPVYEKGSSLASRASSGEVLNGLAKKIPFFVGGSADLAGSNKTTIKNA GDFTAVDYSGKNFWFGVREFAMGAALNGMALHGGLRVFGGTFFVFSDYLRPAIRLAAL MGLPVTYVFTHDSIAVGEDGPTHEPVEQLASLRAMPNLSLIRPADGNETAAAWKLAVQ STDHPTALVLTRQNLPTIDQTSEEALAGVEKGAYVVSKSKNETPDALLIASGSEVGLA IEAQAELAKENIDVSVVSMPSMDRFEKQSDEYKNEVLPADVKKRLAIEMGSSFGWGKY TGLEGDVLGIDRFGASAPGETIINEYGFSVPNVVNRVKALINK*" gene 1919861..1921864 /gene="tktA" /locus_tag="BSU_17890" /old_locus_tag="BSU17890" misc_feature complement(1920065..1920084) /Source="Nicolas_upshift_promotors" /id="U1440" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.713286713286713" /psig="0.78921078921079" /xcortree=31 /SigmaFactorBS="ccactggcggaatcccttaagatcttcaatactaagatcaaa cccgcttaaatgaagcATGCTGTATAATAGTGCTGAcccgtgtccagcagataaaaca a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(1920082) /Source="Nicolas_upshifts" /id="U1440" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.713286713286713" /psig="0.78921078921079" /xcortree=31 /SigmaFactorBS="ccactggcggaatcccttaagatcttcaatactaagatcaaa cccgcttaaatgaagcATGCTGTATAATAGTGCTGAcccgtgtccagcagataaaaca a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" downshifts 1921854 /Source="Nicolas_upshifts" /id="D975" /incds=0 /nref=230 /ntot=257 /MaxReadThrough="4.5478" /MaxDrop="6.66676" /score="16.4587041" /energy="-10.6" /TU="U1439" /idTUdmin="U1436" /TUdmin=0 /isTUend="TRUE" S_feature complement(1921866..1922524) /Source="Nicolas_S_feature" /locus_tag="new_1921866_1922524_c" /HighExp="Lbstat, C30, Salt, BC, S7, LPhT, S8, M0t90, T-0.40H, Glucon" /AntisenseName="yneE" /AntisenseCor="4.3891878649396997E-2" /AntisenseRegPval="-0.3" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="0.604, 0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S661" upshifts 1921964 /Source="Nicolas_upshifts" /id="U1441" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.783216783216783" /psig="0.996003996003996" /xcortree=441 /SigmaFactorBS="tgtttatccgacaaaaatagtattggctgtttaacagtaata gacaattctttcttttcttCTTTTGTATAATAGAGAGCAaatgaaatgctgctggaaa a" /listShort="yneE, yneF, S662, S663, ccdA, yneI" /listLong="yneJ" misc_feature 1921965..1921984 /Source="Nicolas_upshift_promotors" /id="U1441" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.783216783216783" /psig="0.996003996003996" /xcortree=441 /SigmaFactorBS="tgtttatccgacaaaaatagtattggctgtttaacagtaata gacaattctttcttttcttCTTTTGTATAATAGAGAGCAaatgaaatgctgctggaaa a" /listShort="yneE, yneF, S662, S663, ccdA, yneI" /listLong="yneJ" /label="promotor_single_box" /note="Geneious type: promotor_single_box" CDS 1922017..1922463 /gene="pcfA" /locus_tag="BSU_17900" /old_locus_tag="BSU17900" /experiment="publication(s) with functional evidences, PMID:19682252, 25041308, 22720735, 27489185" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 19682252, 25041308, 22720735, 27489185; Product type f: factor" /codon_start=1 /transl_table=11 /product="factor controlling DNA replication" /protein_id="NP_389673.1" /db_xref="EnsemblGenomes-Gn:BSU17900" /db_xref="EnsemblGenomes-Tr:CAB13674" /db_xref="GOA:P45707" /db_xref="InterPro:IPR019683" /db_xref="PDB:4TPS" /db_xref="SubtiList:BG11248" /db_xref="UniProtKB/Swiss-Prot:P45707" /translation="MERHYYTYLIKEEFANHYFGRESVMFELFQDYHWTSLEKQQYEM TEKQIQYITQPIPILHMHQRLKMNLNKTDYRQLDYIYRIALPKAKGHATFMMKEHMIE IVASGDYEAETIFFEVLRKVSPCFLAMDFNSKRYGWLNPVKERNFV*" gene 1922017..1922463 /gene="pcfA" /locus_tag="BSU_17900" /old_locus_tag="BSU17900" misc_feature 1922487..1922506 /Source="Nicolas_upshift_promotors" /id="U1442" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.973026973026973" /psig=1 /xcortree=2574 /SigmaFactorBS="atccggtgaaagaaagaaattttgtctaaaaccgaagaaaaa gagatgtaaaTGTTGTATAATAGCTTTTGGtttagtacactttaaactagacaacatg a" /listShort="yneF, S662, S663, ccdA, yneI, yneJ" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 1922495 /Source="Nicolas_upshifts" /id="U1442" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.973026973026973" /psig=1 /xcortree=2574 /SigmaFactorBS="atccggtgaaagaaagaaattttgtctaaaaccgaagaaaaa gagatgtaaaTGTTGTATAATAGCTTTTGGtttagtacactttaaactagacaacatg a" /listShort="yneF, S662, S663, ccdA, yneI, yneJ" /GFF_Attribute="listLong" promotor_-10 complement(1922506..1922523) /Source="Nicolas_upshift_promotors" /id="U1443" /multdbtbs="-" /comp="M15" /sig="SigA" /pcomp="0.394605394605395" /psig="0.604395604395604" /xcortree=3127 /SigmaFactorBS="aacaacgcccactaggatgccaacccataaagtcatttTATT TcctccttcatgttgtctaGTTTAAAGTGTACTAAACcaaaagctattatacaacatt t" /listShort="S661" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1922524) /Source="Nicolas_upshifts" /id="U1443" /multdbtbs="-" /comp="M15" /sig="SigA" /pcomp="0.394605394605395" /psig="0.604395604395604" /xcortree=3127 /SigmaFactorBS="aacaacgcccactaggatgccaacccataaagtcatttTATT TcctccttcatgttgtctaGTTTAAAGTGTACTAAACcaaaagctattatacaacatt t" /listShort="S661" /GFF_Attribute="listLong" promotor_-35 complement(1922542..1922546) /Source="Nicolas_upshift_promotors" /id="U1443" /multdbtbs="-" /comp="M15" /sig="SigA" /pcomp="0.394605394605395" /psig="0.604395604395604" /xcortree=3127 /SigmaFactorBS="aacaacgcccactaggatgccaacccataaagtcatttTATT TcctccttcatgttgtctaGTTTAAAGTGTACTAAACcaaaagctattatacaacatt t" /listShort="S661" /GFF_Attribute="listLong" /label="promotor_-35" CDS 1922549..1922767 /gene="yneF" /locus_tag="BSU_17910" /old_locus_tag="BSU17910" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative acyltransferase" /protein_id="NP_389674.1" /db_xref="EnsemblGenomes-Gn:BSU17910" /db_xref="EnsemblGenomes-Tr:CAB13675" /db_xref="GOA:P45708" /db_xref="InterPro:IPR005359" /db_xref="SubtiList:BG11249" /db_xref="UniProtKB/Swiss-Prot:P45708" /translation="MTLWVGILVGVVALLIGVALGFFIARKYMMSYLKKNPPINEQML RMMMMQMGMKPSQKKINQMMKAMNNQTK*" gene 1922549..1922767 /gene="yneF" /locus_tag="BSU_17910" /old_locus_tag="BSU17910" downshifts 1922779 /Source="Nicolas_upshifts" /id="D976" /incds=0 /nref=243 /ntot=260 /MaxReadThrough="3.51446" /MaxDrop="7.54782" /score="0.133420982" /energy="-4.3" /TU="U1441,U1442" /idTUdmin="U1439" /TUdmin=287 /isTUend="FALSE" S_feature 1922824..1923123 /Source="Nicolas_S_feature" /locus_tag="new_1922824_1923123" /HighExp="S4, S3, S5, G180, S8, T5.0H, LoTm, G135, S6, S7" /AntisenseName="ynzD" /AntisenseCor="-0.33023056016157298" /AntisenseRegPval="-7.5" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="1, 0.996" /TUlongSig="NA" /TUlongPSig="NA" /label="S662" CDS complement(1922841..1923014) /gene="spo0D" /locus_tag="BSU_17920" /old_locus_tag="BSU17920" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:11679073, 15187183, 17350627, 22303282, 23378509, 27965289" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11679073, 15187183, 17350627, 22303282, 23378509, 27965289; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="Spo0A-P phosphatase" /protein_id="NP_389675.1" /db_xref="EnsemblGenomes-Gn:BSU17920" /db_xref="EnsemblGenomes-Tr:CAB13676" /db_xref="GOA:O31819" /db_xref="InterPro:IPR018540" /db_xref="InterPro:IPR037208" /db_xref="SubtiList:BG13467" /db_xref="UniProtKB/Swiss-Prot:O31819" /translation="MIREHLLKEIEKKRAELLQIVMANGMTSHITIELSQELDHLLIQ YQKQRLRAVAGDE*" gene complement(1922841..1923014) /gene="spo0D" /locus_tag="BSU_17920" /old_locus_tag="BSU17920" downshifts complement(1922854) /Source="Nicolas_upshifts" /id="D977" /incds=0 /nref=109 /ntot=219 /MaxReadThrough="4.0851" /MaxDrop="5.22565" /score="1.92055758" /energy="-4.3" /TU="U1444,U1446" /idTUdmin="U1444" /TUdmin="-88" /isTUend="FALSE" promotor_-10 complement(1923052..1923071) /Source="Nicolas_upshift_promotors" /id="U1444" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.784215784215784" /psig="0.998001998001998" /xcortree=568 /SigmaFactorBS="ttgacattgagacattatactccttctCATTTGAAaattagt ataaatATGGATATAATATAAACATTcactttgaagatctaatgtatgaaaggataca t" /listShort="ynzD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1923059) /Source="Nicolas_upshifts" /id="U1444" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.784215784215784" /psig="0.998001998001998" /xcortree=568 /SigmaFactorBS="ttgacattgagacattatactccttctCATTTGAAaattagt ataaatATGGATATAATATAAACATTcactttgaagatctaatgtatgaaaggataca t" /listShort="ynzD" /GFF_Attribute="listLong" promotor_-35 complement(1923085..1923092) /Source="Nicolas_upshift_promotors" /id="U1444" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.784215784215784" /psig="0.998001998001998" /xcortree=568 /SigmaFactorBS="ttgacattgagacattatactccttctCATTTGAAaattagt ataaatATGGATATAATATAAACATTcactttgaagatctaatgtatgaaaggataca t" /listShort="ynzD" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1923094..1923102 /Source="Nicolas_upshift_promotors" /id="U1445" /multdbtbs="SigA" /comp="M1" /sig="SigH" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=535 /SigmaFactorBS="tatccatatttatactaattttcaaatgaGAAGGAGTAtaat gtctcaaTGTCAAATTAAATTATATAagttttttctgaaaatagaaatccttcaagtg a" /listShort="S663, ccdA, yneI, yneJ" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(1923114..1923133) /Source="Nicolas_upshift_promotors" /id="U1446" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.492507492507492" /psig="0.999000999001" /xcortree=3128 /SigmaFactorBS="catttcatttttttaacactttcacttgaagGATTTCTAttt tcagaaaaaacTTATATAATTTAATTTGACAttgagacattatactccttctcatttg a" /listShort="ynzD, S661" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-10 1923114..1923132 /Source="Nicolas_upshift_promotors" /id="U1445" /multdbtbs="SigA" /comp="M1" /sig="SigH" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=535 /SigmaFactorBS="tatccatatttatactaattttcaaatgaGAAGGAGTAtaat gtctcaaTGTCAAATTAAATTATATAagttttttctgaaaatagaaatccttcaagtg a" /listShort="S663, ccdA, yneI, yneJ" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 1923125..1923233 /Source="Nicolas_S_feature" /locus_tag="new_1923125_1923233" /HighExp="T4.0H, T3.30H, T3.0H, S2, Lbstat, T5.0H, T2.30H, S4, T-1.40H, S3" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigH, SigA, SigA" /TUshortPSig="0.999, 1, 0.996" /TUlongSig="NA" /TUlongPSig="NA" /label="S663" upshifts 1923125 /Source="Nicolas_upshifts" /id="U1445" /multdbtbs="SigA" /comp="M1" /sig="SigH" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=535 /SigmaFactorBS="tatccatatttatactaattttcaaatgaGAAGGAGTAtaat gtctcaaTGTCAAATTAAATTATATAagttttttctgaaaatagaaatccttcaagtg a" /listShort="S663, ccdA, yneI, yneJ" /GFF_Attribute="listLong" upshifts complement(1923126) /Source="Nicolas_upshifts" /id="U1446" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.492507492507492" /psig="0.999000999001" /xcortree=3128 /SigmaFactorBS="catttcatttttttaacactttcacttgaagGATTTCTAttt tcagaaaaaacTTATATAATTTAATTTGACAttgagacattatactccttctcatttg a" /listShort="ynzD, S661" /GFF_Attribute="listLong" promotor_-35 complement(1923148..1923155) /Source="Nicolas_upshift_promotors" /id="U1446" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.492507492507492" /psig="0.999000999001" /xcortree=3128 /SigmaFactorBS="catttcatttttttaacactttcacttgaagGATTTCTAttt tcagaaaaaacTTATATAATTTAATTTGACAttgagacattatactccttctcatttg a" /listShort="ynzD, S661" /GFF_Attribute="listLong" /label="promotor_-35" CDS 1923234..1923941 /gene="ccdA" /locus_tag="BSU_17930" /old_locus_tag="BSU17930" /function="16.10: Respire" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:15849754, 16771673, 16850406, 19682263" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15849754, 16771673, 16850406, 19682263; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="cytochrome c-type biogenesis protein CcdA; thiol-disulfide oxido-reductase" /protein_id="NP_389676.1" /db_xref="EnsemblGenomes-Gn:BSU17930" /db_xref="EnsemblGenomes-Tr:CAB13677" /db_xref="GOA:P45706" /db_xref="InterPro:IPR003834" /db_xref="SubtiList:BG11240" /db_xref="UniProtKB/Swiss-Prot:P45706" /translation="MGDVNYFLTFGAGFLSFISPCCLPLYPAFLSYITGVSMDDVKTE KLLLQKRSLFHTLCFLLGFSVIFIALGYGTSFIGSLFRDYHDAIRQIGALLIILFGFI TLGVFRPEAMMKERRIHFKHKPSGFLGSVLIGMAFAAGWTPCTGPILAAVITLAGTNP GSAVPYMMLYVLGFAVPFLLLSFFITKLKWIRKNQLFIMKAGGVLMIVIGVLLFFNWM SLIIILLSDLFGGFTGF*" gene 1923234..1923941 /gene="ccdA" /locus_tag="BSU_17930" /old_locus_tag="BSU17930" promotor_-35 1923961..1923968 /Source="Nicolas_upshift_promotors" /id="U1447" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.891108891108891" /psig="0.999000999001" /xcortree=2256 /SigmaFactorBS="ttactggtttttgacggtaaattactttcgtacTACTACTAa tccttttgttTTTGGTACAATAAGACTATTatctgtggaaatcgattgttggagggga a" /listShort="yneI, yneJ" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1923980..1923999 /Source="Nicolas_upshift_promotors" /id="U1447" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.891108891108891" /psig="0.999000999001" /xcortree=2256 /SigmaFactorBS="ttactggtttttgacggtaaattactttcgtacTACTACTAa tccttttgttTTTGGTACAATAAGACTATTatctgtggaaatcgattgttggagggga a" /listShort="yneI, yneJ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1923988 /Source="Nicolas_upshifts" /id="U1447" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.891108891108891" /psig="0.999000999001" /xcortree=2256 /SigmaFactorBS="ttactggtttttgacggtaaattactttcgtacTACTACTAa tccttttgttTTTGGTACAATAAGACTATTatctgtggaaatcgattgttggagggga a" /listShort="yneI, yneJ" /GFF_Attribute="listLong" CDS 1924030..1924392 /gene="yneI" /locus_tag="BSU_17940" /old_locus_tag="BSU17940" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 10781554; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative response regulator (CheY homolog)" /protein_id="NP_389677.1" /db_xref="EnsemblGenomes-Gn:BSU17940" /db_xref="EnsemblGenomes-Tr:CAB13678" /db_xref="GOA:P45709" /db_xref="InterPro:IPR001789" /db_xref="InterPro:IPR011006" /db_xref="SubtiList:BG11250" /db_xref="UniProtKB/Swiss-Prot:P45709" /translation="MTRVLVVDDAKFMRVKIREILEEANYIIAGEAADGEQAADLYKK LRPDLVTMDITMPVKNGIKALRDILTFDPKAKVIMCTAMRQQRIVTEAIELGAKDFIV KPFEETKVLEAVSRVMGH*" gene 1924030..1924392 /gene="yneI" /locus_tag="BSU_17940" /old_locus_tag="BSU17940" promotor_-35 1924410..1924413 /Source="Nicolas_upshift_promotors" /id="U1448" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.637362637362637" /psig="0.993006993006993" /xcortree=3154 /SigmaFactorBS="ttatgggacattaaagtcatttcttttcaaaATGGttttttt tattgttTTGGAGTATAGTATATAGTAtcaacactccgagaaacaaaggaatgataag t" /listShort="yneJ" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1924428..1924447 /Source="Nicolas_upshift_promotors" /id="U1448" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.637362637362637" /psig="0.993006993006993" /xcortree=3154 /SigmaFactorBS="ttatgggacattaaagtcatttcttttcaaaATGGttttttt tattgttTTGGAGTATAGTATATAGTAtcaacactccgagaaacaaaggaatgataag t" /listShort="yneJ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1924439 /Source="Nicolas_upshifts" /id="U1448" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.637362637362637" /psig="0.993006993006993" /xcortree=3154 /SigmaFactorBS="ttatgggacattaaagtcatttcttttcaaaATGGttttttt tattgttTTGGAGTATAGTATATAGTAtcaacactccgagaaacaaaggaatgataag t" /listShort="yneJ" /GFF_Attribute="listLong" CDS 1924471..1924962 /gene="yneJ" /locus_tag="BSU_17950" /old_locus_tag="BSU17950" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 10781554, 15849754, 16850406; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative integral inner membrane protein" /protein_id="NP_389678.1" /db_xref="EnsemblGenomes-Gn:BSU17950" /db_xref="EnsemblGenomes-Tr:CAB13679" /db_xref="GOA:P45710" /db_xref="InterPro:IPR009916" /db_xref="InterPro:IPR031306" /db_xref="SubtiList:BG11251" /db_xref="UniProtKB/Swiss-Prot:P45710" /translation="MISMMIIVSSIIAVLMAVAVMVVRIKSSDKPVSPKKIILPPIFM STGALMFLFPVFWVTGAEFLEAFTLGVIFSIFLIKTSKFEIKNNEIYMKRSKAFVFIL VGLLVIRIVMKSILSTSIDYGALSGMFWILAFGMIVPWRIAMYLSYRKLHNELQSSNI QMN*" gene 1924471..1924962 /gene="yneJ" /locus_tag="BSU_17950" /old_locus_tag="BSU17950" downshifts 1924958 /Source="Nicolas_upshifts" /id="D978" /incds=0 /nref=110 /ntot=273 /MaxReadThrough="1.09905" /MaxDrop="5.9692" /score="16.4219082" /energy="-9.7" /TU="NA" /idTUdmin="U1445" /TUdmin=2 /isTUend="TRUE" CDS complement(1924993..1925421) /gene="yneK" /locus_tag="BSU_17960" /old_locus_tag="BSU17960" /experiment="publication(s) with functional evidences, PMID:23060960" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 23060960; Product type f: factor" /codon_start=1 /transl_table=11 /product="factor interacting with DynA" /protein_id="NP_389679.1" /db_xref="EnsemblGenomes-Gn:BSU17960" /db_xref="EnsemblGenomes-Tr:CAB13680" /db_xref="InterPro:IPR020203" /db_xref="SubtiList:BG11252" /db_xref="UniProtKB/Swiss-Prot:P45711" /translation="MLEGWFLWFILFWVIMMVVLLSIGGFFMFRKFLKRLPKEDGRSE LDWQDYYIENSRHLWNDENKQFLDELTAPVPELFRDAAKAKIAGKIGELALKEKVAKI DQQLMIKGYILATPKRDHTFLKRHLRDKKIDLEPYQTLLK*" gene complement(1924993..1925421) /gene="yneK" /locus_tag="BSU_17960" /old_locus_tag="BSU17960" downshifts complement(1925010) /Source="Nicolas_upshifts" /id="D979" /incds=0 /nref=188 /ntot=245 /MaxReadThrough="1.60911" /MaxDrop="5.09033" /score="10.710816" /energy="-9.7" /TU="NA" /idTUdmin="U1449" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(1925439..1925458) /Source="Nicolas_upshift_promotors" /id="U1449" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.796203796203796" /psig="0.999000999001" /xcortree=3159 /SigmaFactorBS="gacgtctatcacttttttctattctttttttaCTGTGTTCtt ctaatctctctTCGTATACAATATGGTTAGAataagggggaatgattgatgctggaag g" /listShort="yneK" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1925451) /Source="Nicolas_upshifts" /id="U1449" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.796203796203796" /psig="0.999000999001" /xcortree=3159 /SigmaFactorBS="gacgtctatcacttttttctattctttttttaCTGTGTTCtt ctaatctctctTCGTATACAATATGGTTAGAataagggggaatgattgatgctggaag g" /listShort="yneK" /GFF_Attribute="listLong" S_feature complement(1925453..1925538) /Source="Nicolas_S_feature" /locus_tag="new_1925453_1925538_c" /HighExp="S8, S6, S7, LBGstat, C30, dia15, S0, Cold, T1.0H, Diami" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigK" /TUshortPSig="0.958, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S664" promotor_-35 complement(1925472..1925479) /Source="Nicolas_upshift_promotors" /id="U1449" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.796203796203796" /psig="0.999000999001" /xcortree=3159 /SigmaFactorBS="gacgtctatcacttttttctattctttttttaCTGTGTTCtt ctaatctctctTCGTATACAATATGGTTAGAataagggggaatgattgatgctggaag g" /listShort="yneK" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1925509..1925518 /Source="Nicolas_upshift_promotors" /id="U1450" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.995004995004995" /psig="0.995004995004995" /xcortree=1415 /SigmaFactorBS="agaagaacacagtaaaaaaagaatagaaaaaagtgatagacG TCTAGTCAAaagagatagtagATCATATTCTATTGTATAGTgaatctgctatttggcc a" /listShort="S665" /GFF_Attribute="listLong" /label="promotor_-35" S_feature 1925528..1925637 /Source="Nicolas_S_feature" /locus_tag="new_1925528_1925637" /HighExp="S8, BT, B36, S7, G/S, Pyr, B60, S6, Glucon, C30" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigK" /TUshortPSig="0.995" /TUlongSig="NA" /TUlongPSig="NA" /label="S665" upshifts 1925528 /Source="Nicolas_upshifts" /id="U1450" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.995004995004995" /psig="0.995004995004995" /xcortree=1415 /SigmaFactorBS="agaagaacacagtaaaaaaagaatagaaaaaagtgatagacG TCTAGTCAAaagagatagtagATCATATTCTATTGTATAGTgaatctgctatttggcc a" /listShort="S665" /GFF_Attribute="listLong" promotor_-10 1925531..1925550 /Source="Nicolas_upshift_promotors" /id="U1450" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.995004995004995" /psig="0.995004995004995" /xcortree=1415 /SigmaFactorBS="agaagaacacagtaaaaaaagaatagaaaaaagtgatagacG TCTAGTCAAaagagatagtagATCATATTCTATTGTATAGTgaatctgctatttggcc a" /listShort="S665" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-10 complement(1925533..1925552) /Source="Nicolas_upshift_promotors" /id="U1451" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.53946053946054" /psig="0.958041958041958" /xcortree=1633 /SigmaFactorBS="atcgtcaaataccctctagtgactctccCATGgccaaatagc agatTCACTATACAATAGAATATGatctactatctcttttgactagacgtctatcact t" /listShort="S664, yneK" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1925538) /Source="Nicolas_upshifts" /id="U1451" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.53946053946054" /psig="0.958041958041958" /xcortree=1633 /SigmaFactorBS="atcgtcaaataccctctagtgactctccCATGgccaaatagc agatTCACTATACAATAGAATATGatctactatctcttttgactagacgtctatcact t" /listShort="S664, yneK" /GFF_Attribute="listLong" S_feature complement(1925540..1925623) /Source="Nicolas_S_feature" /locus_tag="new_1925540_1925623_c" /HighExp="S8, S6, S7, C30, BT, S5, Pyr, Glucon, BC, C90" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigK" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S666" promotor_-35 complement(1925567..1925570) /Source="Nicolas_upshift_promotors" /id="U1451" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.53946053946054" /psig="0.958041958041958" /xcortree=1633 /SigmaFactorBS="atcgtcaaataccctctagtgactctccCATGgccaaatagc agatTCACTATACAATAGAATATGatctactatctcttttgactagacgtctatcact t" /listShort="S664, yneK" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 1925594 /Source="Nicolas_upshifts" /id="D980" /incds=0 /nref=9 /ntot=30 /MaxReadThrough="3.76639" /MaxDrop="5.34013" /score="5.70696998" /energy="-12.7" /TU="U1450" /idTUdmin="U1450" /TUdmin="-44" /isTUend="FALSE" CDS complement(1925655..1926047) /gene="cotM" /locus_tag="BSU_17970" /old_locus_tag="BSU17970" /function="16.13: Shape" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:9068633, 11150673" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9068633, 11150673; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="spore coat protein (outer)" /protein_id="NP_389680.1" /db_xref="EnsemblGenomes-Gn:BSU17970" /db_xref="EnsemblGenomes-Tr:CAB13681" /db_xref="GOA:Q45058" /db_xref="InterPro:IPR008978" /db_xref="SubtiList:BG11822" /db_xref="UniProtKB/Swiss-Prot:Q45058" /translation="MWRNASMNHSKRNDANDFDSMDEWLRQFFEDPFAWYDETLPIDL YETSQQYIIEADLTFLQPTQVTVTLSGCEFILTVKSSGQTFEKQMMLPFYFNDKNIQV ECENQILTVAVNKETEDGSSFSLQFPLS*" gene complement(1925655..1926047) /gene="cotM" /locus_tag="BSU_17970" /old_locus_tag="BSU17970" downshifts complement(1925668) /Source="Nicolas_upshifts" /id="D981" /incds=0 /nref=20 /ntot=92 /MaxReadThrough="4.44864" /MaxDrop="4.9615" /score="11.5991121" /energy="-12.7" /TU="U1454" /idTUdmin="U1456" /TUdmin=486 /isTUend="FALSE" promotor_-35 1925890..1925895 /Source="Nicolas_upshift_promotors" /id="U1452" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.994005994005994" /psig="0.994005994005994" /xcortree=439 /SigmaFactorBS="cttgtgtaggctgtaaaaaagtcagatccgcttctATAATAt actgctgacttgttTCATATAAATCAATAGGCAatgtttcgtcgtaccaggcgaaggg g" /listShort="S667" /listLong="S668, citB, S669, yneN" /label="promotor_-35" promotor_-10 1925911..1925929 /Source="Nicolas_upshift_promotors" /id="U1452" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.994005994005994" /psig="0.994005994005994" /xcortree=439 /SigmaFactorBS="cttgtgtaggctgtaaaaaagtcagatccgcttctATAATAt actgctgacttgttTCATATAAATCAATAGGCAatgtttcgtcgtaccaggcgaaggg g" /listShort="S667" /listLong="S668, citB, S669, yneN" /label="promotor_-10" upshifts 1925915 /Source="Nicolas_upshifts" /id="U1452" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.994005994005994" /psig="0.994005994005994" /xcortree=439 /SigmaFactorBS="cttgtgtaggctgtaaaaaagtcagatccgcttctATAATAt actgctgacttgttTCATATAAATCAATAGGCAatgtttcgtcgtaccaggcgaaggg g" /listShort="S667" /listLong="S668, citB, S669, yneN" promotor_-35 1926025..1926029 /Source="Nicolas_upshift_promotors" /id="U1453" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp=1 /psig=0 /xcortree=1243 /SigmaFactorBS="aatcattcgcatcgttgcgttttgaatggTTCATggaagcat tCCTCCACATATCAACcttgctttacatcatatgcggtggattataaatgggtgaacg c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1926039..1926053 /Source="Nicolas_upshift_promotors" /id="U1453" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp=1 /psig=0 /xcortree=1243 /SigmaFactorBS="aatcattcgcatcgttgcgttttgaatggTTCATggaagcat tCCTCCACATATCAACcttgctttacatcatatgcggtggattataaatgggtgaacg c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-10 complement(1926054..1926073) /Source="Nicolas_upshift_promotors" /id="U1454" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1290 /SigmaFactorBS="aagaaaagcagaccttagtgtctgtttttttatGCGTTCACC CatttataatccacCGCATATGATGTAAAGCAAGgttgatatgtggaggaatgcttcc a" /listShort="cotM, S666, S664, yneK" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1926056 /Source="Nicolas_upshifts" /id="U1453" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp=1 /psig=0 /xcortree=1243 /SigmaFactorBS="aatcattcgcatcgttgcgttttgaatggTTCATggaagcat tCCTCCACATATCAACcttgctttacatcatatgcggtggattataaatgggtgaacg c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" upshifts complement(1926069) /Source="Nicolas_upshifts" /id="U1454" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1290 /SigmaFactorBS="aagaaaagcagaccttagtgtctgtttttttatGCGTTCACC CatttataatccacCGCATATGATGTAAAGCAAGgttgatatgtggaggaatgcttcc a" /listShort="cotM, S666, S664, yneK" /GFF_Attribute="listLong" promotor_-35 complement(1926087..1926096) /Source="Nicolas_upshift_promotors" /id="U1454" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1290 /SigmaFactorBS="aagaaaagcagaccttagtgtctgtttttttatGCGTTCACC CatttataatccacCGCATATGATGTAAAGCAAGgttgatatgtggaggaatgcttcc a" /listShort="cotM, S666, S664, yneK" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(1926128..1926274) /gene="sspP" /locus_tag="BSU_17980" /old_locus_tag="BSU17980" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:10806362" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10806362; Product type f: factor" /codon_start=1 /transl_table=11 /product="small acid-soluble spore protein" /protein_id="NP_389681.1" /db_xref="EnsemblGenomes-Gn:BSU17980" /db_xref="EnsemblGenomes-Tr:CAB13682" /db_xref="GOA:P71032" /db_xref="InterPro:IPR012614" /db_xref="SubtiList:BG11921" /db_xref="UniProtKB/Swiss-Prot:P71032" /translation="MTNKNTSKDMHKNAPKGHNPGQPEPLSGSKKVKNRNHTRQKHNS SHDM*" gene complement(1926128..1926274) /gene="sspP" /locus_tag="BSU_17980" /old_locus_tag="BSU17980" downshifts complement(1926149) /Source="Nicolas_upshifts" /id="D982" /incds=0 /nref=42 /ntot=61 /MaxReadThrough="1.80349" /MaxDrop="6.88836" /score="0.778507843" /energy="-4.3" /TU="NA" /idTUdmin="U1456" /TUdmin=5 /isTUend="TRUE" CDS complement(1926306..1926452) /gene="sspO" /locus_tag="BSU_17990" /old_locus_tag="BSU17990" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:9852018, 10806362" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9852018, 10806362; Product type s: structure" /codon_start=1 /transl_table=11 /product="small acid-soluble spore protein" /protein_id="NP_389682.1" /db_xref="EnsemblGenomes-Gn:BSU17990" /db_xref="EnsemblGenomes-Tr:CAB13683" /db_xref="GOA:P71031" /db_xref="InterPro:IPR012613" /db_xref="SubtiList:BG11920" /db_xref="UniProtKB/Swiss-Prot:P71031" /translation="MVKRKANHVINGMNDAKSQGKGAGYIENDQLVLTEAERQNNKKR KTNQ*" gene complement(1926306..1926452) /gene="sspO" /locus_tag="BSU_17990" /old_locus_tag="BSU17990" S_feature 1926452..1926585 /Source="Nicolas_S_feature" /locus_tag="new_1926452_1926585" /HighExp="S8, S7, S3, S6, LoTm, S4, S5, BT, Pyr, C30" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigEF" /TUshortPSig="0.994" /TUlongSig="NA" /TUlongPSig="NA" /label="S667" upshifts 1926452 /Source="Nicolas_upshifts" /id="U1455" /multdbtbs="-" /comp="M19" /sig="Sig-" /pcomp="0.228771228771229" /psig="0.312687312687313" /xcortree=1215 /SigmaFactorBS="tgccttggctttttgcgtcattcattccgttaatgacgtgat tcgcttttcttttgaccatcattatcaccTCAatcataatatggcttcttttattgtg t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" misc_feature 1926463..1926465 /Source="Nicolas_upshift_promotors" /id="U1455" /multdbtbs="-" /comp="M19" /sig="Sig-" /pcomp="0.228771228771229" /psig="0.312687312687313" /xcortree=1215 /SigmaFactorBS="tgccttggctttttgcgtcattcattccgttaatgacgtgat tcgcttttcttttgaccatcattatcaccTCAatcataatatggcttcttttattgtg t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" promotor_-10 complement(1926468..1926479) /Source="Nicolas_upshift_promotors" /id="U1456" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp="0.977022977022977" /psig="0.977022977022977" /xcortree=837 /SigmaFactorBS="ttatgagaaaaatgtaccggtaatttttactgtttacgctct CTCATATaacacaataaaagaAGCCATATTATGattgaggtgataatgatggtcaaaa g" /listShort="sspO, sspP" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1926482) /Source="Nicolas_upshifts" /id="U1456" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp="0.977022977022977" /psig="0.977022977022977" /xcortree=837 /SigmaFactorBS="ttatgagaaaaatgtaccggtaatttttactgtttacgctct CTCATATaacacaataaaagaAGCCATATTATGattgaggtgataatgatggtcaaaa g" /listShort="sspO, sspP" /GFF_Attribute="listLong" promotor_-35 complement(1926494..1926500) /Source="Nicolas_upshift_promotors" /id="U1456" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp="0.977022977022977" /psig="0.977022977022977" /xcortree=837 /SigmaFactorBS="ttatgagaaaaatgtaccggtaatttttactgtttacgctct CTCATATaacacaataaaagaAGCCATATTATGattgaggtgataatgatggtcaaaa g" /listShort="sspO, sspP" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1926575..1926582 /Source="Nicolas_upshift_promotors" /id="U1457" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.956043956043956" /psig=1 /xcortree=2774 /SigmaFactorBS="tacatttttctcataagtcgaacttattgtatttaataaaaa cattgaTATTTACTtatgtatgattttgTTTTAATATGAAATTGTGAGaaaattgtga t" /listShort="S668, citB, S669, yneN, ynzL, sspN, tlp" /GFF_Attribute="listLong" /label="promotor_-35" S_feature 1926587..1926679 /Source="Nicolas_S_feature" /locus_tag="new_1926587_1926679" /HighExp="B60, M40t90, T0.0H, HiOs, T4.0H, T5.0H, T2.30H, M0t90, Sw, T-1.40H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="SigEF" /TUlongPSig="0.994" /label="S668" upshifts 1926587 /Source="Nicolas_upshifts" /id="U1457" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.956043956043956" /psig=1 /xcortree=2774 /SigmaFactorBS="tacatttttctcataagtcgaacttattgtatttaataaaaa cattgaTATTTACTtatgtatgattttgTTTTAATATGAAATTGTGAGaaaattgtga t" /listShort="S668, citB, S669, yneN, ynzL, sspN, tlp" /GFF_Attribute="listLong" promotor_-10 1926597..1926616 /Source="Nicolas_upshift_promotors" /id="U1457" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.956043956043956" /psig=1 /xcortree=2774 /SigmaFactorBS="tacatttttctcataagtcgaacttattgtatttaataaaaa cattgaTATTTACTtatgtatgattttgTTTTAATATGAAATTGTGAGaaaattgtga t" /listShort="S668, citB, S669, yneN, ynzL, sspN, tlp" /GFF_Attribute="listLong" /label="promotor_-10" downshifts complement(1926638) /Source="Nicolas_upshifts" /id="D983" /incds=0 /nref=1 /ntot=67 /MaxReadThrough="2.77282" /MaxDrop="4.02811" /score="0.778507843" /energy="-4.3" /TU="NA" /idTUdmin="U1458" /TUdmin=0 /isTUend="TRUE" CDS 1926680..1929409 /gene="citB" /locus_tag="BSU_18000" /old_locus_tag="BSU18000" /EC_number="4.2.1.3" /function="16.11: Scavenge (Catabolism)" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:9642180, 10468622, 10656796, 14636591, 16395550, 16923907, 22720735, 23354745" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9642180, 10468622, 10656796, 14636591, 16395550, 16923907, 22720735, 23354745; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="aconitate hydratase (bifunctional aconitase)" /protein_id="NP_389683.1" /db_xref="EnsemblGenomes-Gn:BSU18000" /db_xref="EnsemblGenomes-Tr:CAB13684" /db_xref="GOA:P09339" /db_xref="InterPro:IPR000573" /db_xref="InterPro:IPR001030" /db_xref="InterPro:IPR006249" /db_xref="InterPro:IPR015928" /db_xref="InterPro:IPR015931" /db_xref="InterPro:IPR015932" /db_xref="InterPro:IPR018136" /db_xref="InterPro:IPR036008" /db_xref="SubtiList:BG10478" /db_xref="UniProtKB/Swiss-Prot:P09339" /translation="MANEQKTAAKDVFQARKTFTTNGKTYHYYSLKALEDSGIGKVSK LPYSIKVLLESVLRQVDGFVIKKEHVENLAKWGTAELKDIDVPFKPSRVILQDFTGVP AVVDLASLRKAMAAVGGDPDKINPEIPVDLVIDHSVQVDKAGTEDALAVNMDLEFERN AERYKFLSWAKKAFNNYQAVPPATGIVHQVNLEFLASVVHAIEEDGELVTYPDTLVGT DSHTTMINGIGVLGWGVGGIEAEAGMLGQPSYFPVPEVIGAKLVGKLPNGTTATDLAL KVTQVLREKGVVGKFVEFFGPGIAELPLADRATIANMAPEYGATCGFFPVDEEALNYL RLTGRDPEHIDVVEAYCRSNGLFYTPDAEDPQFTDVVEIDLSQIEANLSGPKRPQDLI PLSAMQETFKKQLVSPAGNQGFGLNAEEENKEIKFKLLNGEETVMKTGAIAIAAITSC TNTSNPYVLIGAGLVAKKAVELGLKVPNYVKTSLAPGSKVVTGYLVNSGLLPYMKELG FNLVGYGCTTCIGNSGPLSPEIEEAVAKNDLLITSVLSGNRNFEGRIHPLVKGNYLAS PPLVVAYALAGTVNINLKTDPIGVGKDGQNVYFNDIWPSMDEINALVKQTVTPELFRK EYETVFDDNKRWNEIETTDEALYKWDNDSTYIQNPPFFEEMSVEPGKVEPLKGLRVVG KFGDSVTTDHISPAGAIGKDTPAGKYLQEKGVSPRDFNSYGSRRGNHEVMMRGTFANI RIKNQIAPGTEGGFTTYWPTGEVTSIYDACMKYKEDKTGLVVLAGKDYGMGSSRDWAA KGTNLLGIRTVIAESFERIHRSNLVFMGVLPLQFKQGENADTLGLTGKEVIEVDVDET VRPRDLVTVRAINEDGNVTTFEAVVRFDSEVEIDYYRHGGILQMVLREKMKQS*" gene 1926680..1929409 /gene="citB" /locus_tag="BSU_18000" /old_locus_tag="BSU18000" misc_feature complement(1926700..1926704) /Source="Nicolas_upshift_promotors" /id="U1458" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.95104895104895" /psig="0.001998001998002" /xcortree=88 /SigmaFactorBS="agtaatgatatgttttcccatttgtagtaaacgtttttctcg cttggaaaacgtcttttgCTGCAgttttttgctcgtttgccattctccaaaatccccc t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(1926704) /Source="Nicolas_upshifts" /id="U1458" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.95104895104895" /psig="0.001998001998002" /xcortree=88 /SigmaFactorBS="agtaatgatatgttttcccatttgtagtaaacgtttttctcg cttggaaaacgtcttttgCTGCAgttttttgctcgtttgccattctccaaaatccccc t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" S_feature 1929410..1929480 /Source="Nicolas_S_feature" /locus_tag="new_1929410_1929480" /HighExp="M9-stat, B60, M40t90, Glucon, M0t90, MG-0.2, Mal, T2.30H, MG-0.1, T2.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="SigEF" /TUlongPSig="0.994" /label="S669" CDS 1929481..1929993 /gene="yneN" /locus_tag="BSU_18010" /old_locus_tag="BSU18010" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15342593; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative membrane-bound proteins with a thioredoxin-like domain" /protein_id="NP_389684.1" /db_xref="EnsemblGenomes-Gn:BSU18010" /db_xref="EnsemblGenomes-Tr:CAB13685" /db_xref="GOA:O31820" /db_xref="InterPro:IPR000866" /db_xref="InterPro:IPR013766" /db_xref="InterPro:IPR036249" /db_xref="SubtiList:BG13451" /db_xref="UniProtKB/Swiss-Prot:O31820" /translation="MLKKWLAGILLIMLVGYTGWNLYQTYSKKEVGIQEGQQAPDFSL KTLSGEKSSLQDAKGKKVLLNFWATWCKPCRQEMPAMEKLQKEYADKLAVVAVNFTSA EKSEKQVRAFADTYDLTFPILIDKKGINADYNVMSYPTTYILDEKGVIQDIHVGTMTK KEMEQKLDLD*" gene 1929481..1929993 /gene="yneN" /locus_tag="BSU_18010" /old_locus_tag="BSU18010" downshifts 1929950 /Source="Nicolas_upshifts" /id="D984" /incds=0 /nref=115 /ntot=218 /MaxReadThrough="3.76369" /MaxDrop="5.09954" /score="13.5401842" /energy="-6.9" /TU="U1457" /idTUdmin="U1457" /TUdmin="-726" /isTUend="FALSE" promotor_-35 1930019..1930025 /Source="Nicolas_upshift_promotors" /id="U1459" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.715284715284715" /psig="0.715284715284715" /xcortree=1010 /SigmaFactorBS="actggatcttgattagattcagttttttttatactcaaataT GCTTACaagttttcagaattGGAAAAAATAAAagaatatgcggaggtgagaagcgtga a" /listShort="ynzL, sspN, tlp" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 1930038 /Source="Nicolas_upshifts" /id="U1459" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.715284715284715" /psig="0.715284715284715" /xcortree=1010 /SigmaFactorBS="actggatcttgattagattcagttttttttatactcaaataT GCTTACaagttttcagaattGGAAAAAATAAAagaatatgcggaggtgagaagcgtga a" /listShort="ynzL, sspN, tlp" /GFF_Attribute="listLong" promotor_-10 1930040..1930051 /Source="Nicolas_upshift_promotors" /id="U1459" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.715284715284715" /psig="0.715284715284715" /xcortree=1010 /SigmaFactorBS="actggatcttgattagattcagttttttttatactcaaataT GCTTACaagttttcagaattGGAAAAAATAAAagaatatgcggaggtgagaagcgtga a" /listShort="ynzL, sspN, tlp" /GFF_Attribute="listLong" /label="promotor_-10" CDS 1930074..1930199 /gene="ynzL" /locus_tag="BSU_18019" /old_locus_tag="BSU18019" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="YP_003097732.1" /db_xref="EnsemblGenomes-Gn:BSU18019" /db_xref="EnsemblGenomes-Tr:CAX52626" /db_xref="InterPro:IPR025004" /db_xref="UniProtKB/Swiss-Prot:C0H418" /translation="MKKMRKRSFHELVMENKKELMTNTEYLNQLEEKLEQRFKQK*" gene 1930074..1930199 /gene="ynzL" /locus_tag="BSU_18019" /old_locus_tag="BSU18019" downshifts complement(1930092) /Source="Nicolas_upshifts" /id="D985" /incds=0 /nref=1 /ntot=8 /MaxReadThrough="3.12259" /MaxDrop="3.48183" /score="-0.0160782027" /energy="-13.9" /TU="NA" /idTUdmin="U1462" /TUdmin=1298 /isTUend="FALSE" promotor_-35 1930213..1930219 /Source="Nicolas_upshift_promotors" /id="U1460" /multdbtbs="SigF,SigG" /comp="M8" /sig="SigGF" /pcomp="0.844155844155844" /psig="0.844155844155844" /xcortree=843 /SigmaFactorBS="gaacagcgatttaagcaaaaataacctttaatttgtaTTCAT GTttacccctccttttGAGAAACCTATCtgttgaggagggataaacatgggaaacaac a" /listShort="sspN, tlp" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1930234..1930245 /Source="Nicolas_upshift_promotors" /id="U1460" /multdbtbs="SigF,SigG" /comp="M8" /sig="SigGF" /pcomp="0.844155844155844" /psig="0.844155844155844" /xcortree=843 /SigmaFactorBS="gaacagcgatttaagcaaaaataacctttaatttgtaTTCAT GTttacccctccttttGAGAAACCTATCtgttgaggagggataaacatgggaaacaac a" /listShort="sspN, tlp" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1930236 /Source="Nicolas_upshifts" /id="U1460" /multdbtbs="SigF,SigG" /comp="M8" /sig="SigGF" /pcomp="0.844155844155844" /psig="0.844155844155844" /xcortree=843 /SigmaFactorBS="gaacagcgatttaagcaaaaataacctttaatttgtaTTCAT GTttacccctccttttGAGAAACCTATCtgttgaggagggataaacatgggaaacaac a" /listShort="sspN, tlp" /GFF_Attribute="listLong" CDS 1930264..1930410 /gene="sspN" /locus_tag="BSU_18020" /old_locus_tag="BSU18020" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:10333516" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10333516; Product type f: factor" /codon_start=1 /transl_table=11 /product="small acid-soluble spore protein" /protein_id="YP_054579.2" /db_xref="EnsemblGenomes-Gn:BSU18020" /db_xref="EnsemblGenomes-Tr:CAE01455" /db_xref="GOA:Q7WY69" /db_xref="InterPro:IPR012612" /db_xref="SubtiList:BG14179" /db_xref="UniProtKB/Swiss-Prot:Q7WY69" /translation="MGNNKKNGQPQYAPSHLGTKPVKYKANKGEKMHDTSGQRPIIMQ TKGE*" gene 1930264..1930410 /gene="sspN" /locus_tag="BSU_18020" /old_locus_tag="BSU18020" CDS 1930447..1930698 /gene="sspT" /locus_tag="BSU_18030" /old_locus_tag="BSU18030" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:10333516" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10333516; Product type f: factor" /codon_start=1 /transl_table=11 /product="small acid-soluble spore protein (thioredoxin-like protein)" /protein_id="NP_389685.1" /db_xref="EnsemblGenomes-Gn:BSU18030" /db_xref="EnsemblGenomes-Tr:CAB13686" /db_xref="GOA:Q45060" /db_xref="InterPro:IPR017524" /db_xref="SubtiList:BG11806" /db_xref="UniProtKB/Swiss-Prot:Q45060" /translation="MTKNQNQYQQPNPDDRSDNVEKLQDMVQNTIENIEEAEASMEFA SGEDKQRIKEKNARREQSIEAFRNEIQDESAARQNGYRS*" gene 1930447..1930698 /gene="sspT" /locus_tag="BSU_18030" /old_locus_tag="BSU18030" downshifts 1930676 /Source="Nicolas_upshifts" /id="D986" /incds=0 /nref=41 /ntot=49 /MaxReadThrough="2.07653" /MaxDrop="7.06685" /score="32.1193211" /energy="-7" /TU="NA" /idTUdmin="U1457" /TUdmin=0 /isTUend="TRUE" promotor_-35 1930719..1930724 /Source="Nicolas_upshift_promotors" /id="U1461" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.68031968031968" /psig=1 /xcortree=2003 /SigmaFactorBS="acggataccgttcttaaaaaaccagggaaacctggttTTTTT CtttctgatttgatTATGGTAAAATGGGGCTAAAttgacgttaagggagcagagtaat c" /listShort="S670, yneP, yneQ" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1930738..1930757 /Source="Nicolas_upshift_promotors" /id="U1461" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.68031968031968" /psig=1 /xcortree=2003 /SigmaFactorBS="acggataccgttcttaaaaaaccagggaaacctggttTTTTT CtttctgatttgatTATGGTAAAATGGGGCTAAAttgacgttaagggagcagagtaat c" /listShort="S670, yneP, yneQ" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 1930742..1930833 /Source="Nicolas_S_feature" /locus_tag="new_1930742_1930833" /HighExp="Etha, dia5, dia15, Diami, H2O2, G180, Salt, G150, BMM, G135" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S670" upshifts 1930742 /Source="Nicolas_upshifts" /id="U1461" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.68031968031968" /psig=1 /xcortree=2003 /SigmaFactorBS="acggataccgttcttaaaaaaccagggaaacctggttTTTTT CtttctgatttgatTATGGTAAAATGGGGCTAAAttgacgttaagggagcagagtaat c" /listShort="S670, yneP, yneQ" /GFF_Attribute="listLong" CDS 1930834..1931199 /gene="yneP" /locus_tag="BSU_18040" /old_locus_tag="BSU18040" /EC_number="3.1.2.-" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 11959124, 11994151, 16294310, 18338382; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="acyl-CoA thioesterase" /protein_id="YP_054580.1" /db_xref="EnsemblGenomes-Gn:BSU18040" /db_xref="EnsemblGenomes-Tr:CAB13687" /db_xref="GOA:Q45061" /db_xref="InterPro:IPR006683" /db_xref="InterPro:IPR006684" /db_xref="InterPro:IPR029069" /db_xref="SubtiList:BG11823" /db_xref="UniProtKB/Swiss-Prot:Q45061" /translation="MGIVYHANYLVWMEVGRTALIKDLGFLYSDMEKKGVLSPVVDIN ISYKKPLHYGETAVVHTWIEDYNGFKTVYGYHIYNPAGELSIKATSSHICVDKESFKP IQFRKAFPDWHTAYEKAKK*" gene 1930834..1931199 /gene="yneP" /locus_tag="BSU_18040" /old_locus_tag="BSU18040" CDS 1931215..1931514 /gene="yneQ" /locus_tag="BSU_18050" /old_locus_tag="BSU18050" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_389687.1" /db_xref="EnsemblGenomes-Gn:BSU18050" /db_xref="EnsemblGenomes-Tr:CAB13688" /db_xref="SubtiList:BG11824" /db_xref="UniProtKB/Swiss-Prot:Q45062" /translation="MAFGVKREELNRWKQAVKRGEIAFLTHYWLDDRFPEAKTVTKAG CADIDKLVQWGAAYGLKKEWIHKKSEFPHFDLLGETQKYILEQENLTDHLIRFHL*" gene 1931215..1931514 /gene="yneQ" /locus_tag="BSU_18050" /old_locus_tag="BSU18050" downshifts 1931490 /Source="Nicolas_upshifts" /id="D987" /incds=0 /nref=55 /ntot=217 /MaxReadThrough="3.04989" /MaxDrop="5.5978" /score="-4.41102273" /energy="-6" /TU="NA" /idTUdmin="U1461" /TUdmin=0 /isTUend="TRUE" CDS complement(1931545..1931832) /gene="yneR" /locus_tag="BSU_18060" /old_locus_tag="BSU18060" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 22333191, 23176286" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_389688.1" /db_xref="EnsemblGenomes-Gn:BSU18060" /db_xref="EnsemblGenomes-Tr:CAB13689" /db_xref="InterPro:IPR000361" /db_xref="InterPro:IPR008326" /db_xref="InterPro:IPR035903" /db_xref="SubtiList:BG11825" /db_xref="UniProtKB/Swiss-Prot:Q45063" /translation="MNMTINEDALNWYKEELDLESGDQVRFFVRYGGCSNVQKGFSLG VAKDAPQEAGVTAEADGITFFIEESDLWYFDNHDLLVSYSEDADEPVFEYQ*" gene complement(1931545..1931832) /gene="yneR" /locus_tag="BSU_18060" /old_locus_tag="BSU18060" downshifts complement(1931566) /Source="Nicolas_upshifts" /id="D988" /incds=0 /nref=216 /ntot=260 /MaxReadThrough="3.77766" /MaxDrop="7.20006" /score="-5.4451498" /energy="-6" /TU="U1462,U1463" /idTUdmin="U1463" /TUdmin="-154" /isTUend="FALSE" downshifts complement(1931632) /Source="Nicolas_upshifts" /id="D989" /incds=1 /nref=1 /ntot=1 /MaxReadThrough="7.5674" /MaxDrop="3.11178" /score="-5.4451498" /energy="-6" /TU="U1462,U1463" /idTUdmin="U1463" /TUdmin="-220" /isTUend="FALSE" promotor_-10 complement(1931862..1931881) /Source="Nicolas_upshift_promotors" /id="U1462" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.755244755244755" /psig="0.999000999001" /xcortree=2062 /SigmaFactorBS="gtaaaatggttataagcttaaaaaacttctCTTTTGACacag aatagcctaatACGTTTATAATAGAGAAAATtcaaatgaagaacaaaggggtgttctg t" /listShort="yneR" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1931874) /Source="Nicolas_upshifts" /id="U1462" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.755244755244755" /psig="0.999000999001" /xcortree=2062 /SigmaFactorBS="gtaaaatggttataagcttaaaaaacttctCTTTTGACacag aatagcctaatACGTTTATAATAGAGAAAATtcaaatgaagaacaaaggggtgttctg t" /listShort="yneR" /GFF_Attribute="listLong" promotor_-35 complement(1931897..1931904) /Source="Nicolas_upshift_promotors" /id="U1462" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.755244755244755" /psig="0.999000999001" /xcortree=2062 /SigmaFactorBS="gtaaaatggttataagcttaaaaaacttctCTTTTGACacag aatagcctaatACGTTTATAATAGAGAAAATtcaaatgaagaacaaaggggtgttctg t" /listShort="yneR" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(1931920..1932501) /gene="plsY" /locus_tag="BSU_18070" /old_locus_tag="BSU18070" /function="16.13: Shape" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:12682299, 15849754, 16850406, 16949372, 17005971, 17308305, 17557823, 17645809, 19282621, 26644587" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12682299, 15849754, 16850406, 16949372, 17005971, 17308305, 17557823, 17645809, 19282621, 26644587; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="acylphosphate:glycerol-3-phosphate O-acyltransferase" /protein_id="NP_389689.1" /db_xref="EnsemblGenomes-Gn:BSU18070" /db_xref="EnsemblGenomes-Tr:CAB13690" /db_xref="GOA:Q45064" /db_xref="InterPro:IPR003811" /db_xref="SubtiList:BG11826" /db_xref="UniProtKB/Swiss-Prot:Q45064" /translation="MLIALLIILAYLIGSIPSGLIVGKLAKGIDIREHGSGNLGATNA FRTLGVKAGSVVIAGDILKGTLATALPFLMHVDIHPLLAGVFAVLGHVFPIFAKFKGG KAVATSGGVLLFYAPLLFITMVAVFFIFLYLTKFVSLSSMLTGIYTVIYSFFVHDTYL LIVVTLLTIFVIYRHRANIKRIINKTEPKVKWL*" gene complement(1931920..1932501) /gene="plsY" /locus_tag="BSU_18070" /old_locus_tag="BSU18070" S_feature 1932502..1932632 /Source="Nicolas_S_feature" /locus_tag="new_1932502_1932632" /HighExp="C30, S8, S7, S5, S6, S4, BC, S3, T4.0H, H2O2" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="NA" /TUshortPSig="NA" /TUlongSig="NA" /TUlongPSig="NA" /label="S671" misc_feature complement(1932527..1932546) /Source="Nicolas_upshift_promotors" /id="U1463" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.994005994005994" /psig=1 /xcortree=2140 /SigmaFactorBS="tttgatttgatttgtaagcaaactttacaaaaaaacttatca tcagatcatgacatctCATGTTAAAATAAAAAGAAGggaatttgaaaaaggagaaatg t" /listShort="plsY, yneR" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(1932544) /Source="Nicolas_upshifts" /id="U1463" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.994005994005994" /psig=1 /xcortree=2140 /SigmaFactorBS="tttgatttgatttgtaagcaaactttacaaaaaaacttatca tcagatcatgacatctCATGTTAAAATAAAAAGAAGggaatttgaaaaaggagaaatg t" /listShort="plsY, yneR" /GFF_Attribute="listLong" promotor_-35 1932617..1932620 /Source="Nicolas_upshift_promotors" /id="U1464" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.52047952047952" /psig="0.998001998001998" /xcortree=3133 /SigmaFactorBS="tttgtaaagtttgcttacaaatcaaatcaaacatgcatcata tTTTGatttctcctgttttgATCGTGTAAAATAAGTGAAAaaggagtgacacacgatg c" /listShort="yneT, S672, parE, parC" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 1932634 /Source="Nicolas_upshifts" /id="U1464" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.52047952047952" /psig="0.998001998001998" /xcortree=3133 /SigmaFactorBS="tttgtaaagtttgcttacaaatcaaatcaaacatgcatcata tTTTGatttctcctgttttgATCGTGTAAAATAAGTGAAAaaggagtgacacacgatg c" /listShort="yneT, S672, parE, parC" /GFF_Attribute="listLong" promotor_-10 1932636..1932655 /Source="Nicolas_upshift_promotors" /id="U1464" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.52047952047952" /psig="0.998001998001998" /xcortree=3133 /SigmaFactorBS="tttgtaaagtttgcttacaaatcaaatcaaacatgcatcata tTTTGatttctcctgttttgATCGTGTAAAATAAGTGAAAaaggagtgacacacgatg c" /listShort="yneT, S672, parE, parC" /GFF_Attribute="listLong" /label="promotor_-10" CDS 1932671..1933078 /gene="yneT" /locus_tag="BSU_18080" /old_locus_tag="BSU18080" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 22938038; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative acyl-CoA-binding protein" /protein_id="NP_389690.1" /db_xref="EnsemblGenomes-Gn:BSU18080" /db_xref="EnsemblGenomes-Tr:CAB13691" /db_xref="GOA:Q45065" /db_xref="InterPro:IPR003781" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG11827" /db_xref="UniProtKB/Swiss-Prot:Q45065" /translation="MQNPSKAEIKEILQRSKRIAVVGLSDRPDRTSHMVSKAMQDAGY EIIPVNPTIDEALGVKAVSSLKEIDGPIDIVNVFRRSEQLPGVAEEFLETDAPVFWAQ QGLVNEEAYQMLKEKGRTVIMDLCIKVAHAVTK*" gene 1932671..1933078 /gene="yneT" /locus_tag="BSU_18080" /old_locus_tag="BSU18080" downshifts 1933074 /Source="Nicolas_upshifts" /id="D990" /incds=0 /nref=63 /ntot=221 /MaxReadThrough="4.35976" /MaxDrop="5.49229" /score="-2.11194139" /energy="-6" /TU="U1464" /idTUdmin="U1461" /TUdmin=1584 /isTUend="FALSE" promotor_-35 1933140..1933143 /Source="Nicolas_upshift_promotors" /id="U1465" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.554445554445554" /psig="0.998001998001998" /xcortree=2328 /SigmaFactorBS="taaattcaaggatttttgctttttaattttaagatattGTTT gcgtattacggtgaAACAGATACAATAAAGCTTGaacagctttttttgaataccttgt c" /listShort="S672, parE, parC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1933158..1933177 /Source="Nicolas_upshift_promotors" /id="U1465" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.554445554445554" /psig="0.998001998001998" /xcortree=2328 /SigmaFactorBS="taaattcaaggatttttgctttttaattttaagatattGTTT gcgtattacggtgaAACAGATACAATAAAGCTTGaacagctttttttgaataccttgt c" /listShort="S672, parE, parC" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 1933162..1933476 /Source="Nicolas_S_feature" /locus_tag="new_1933162_1933476" /HighExp="H2O2, G150, G180, Etha, Oxctl, LBGexp, dia0, Lbexp, M40t45, G135" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="0.998, 0.998" /TUlongSig="NA" /TUlongPSig="NA" /label="S672" upshifts 1933162 /Source="Nicolas_upshifts" /id="U1465" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.554445554445554" /psig="0.998001998001998" /xcortree=2328 /SigmaFactorBS="taaattcaaggatttttgctttttaattttaagatattGTTT gcgtattacggtgaAACAGATACAATAAAGCTTGaacagctttttttgaataccttgt c" /listShort="S672, parE, parC" /GFF_Attribute="listLong" CDS 1933477..1935444 /gene="parE" /locus_tag="BSU_18090" /old_locus_tag="BSU18090" /EC_number="5.99.1.3" /function="16.2: Construct biomass (Anabolism)" /function="16.9: Replicate" /experiment="publication(s) with functional evidences, PMID:8969507, 9539793, 12682299, 16267290" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8969507, 9539793, 12682299, 16267290; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="subunit B of DNA topoisomerase IV (ATP-dependent)" /protein_id="NP_389691.2" /db_xref="EnsemblGenomes-Gn:BSU18090" /db_xref="EnsemblGenomes-Tr:CAB13692" /db_xref="GOA:Q59192" /db_xref="InterPro:IPR001241" /db_xref="InterPro:IPR002288" /db_xref="InterPro:IPR003594" /db_xref="InterPro:IPR005740" /db_xref="InterPro:IPR006171" /db_xref="InterPro:IPR013506" /db_xref="InterPro:IPR013759" /db_xref="InterPro:IPR013760" /db_xref="InterPro:IPR014721" /db_xref="InterPro:IPR018522" /db_xref="InterPro:IPR020568" /db_xref="InterPro:IPR036890" /db_xref="SubtiList:BG11804" /db_xref="UniProtKB/Swiss-Prot:Q59192" /translation="MARKQQFDYNEDAIQVLEGLEAVRKRPGMYIGSTDARGLHHLVY EIVDNSVDEVLAGHGDHIIVKIHKDNSISVQDRGRGMPTGMHKLGKPTPEVILTVLHA GGKFGQGGYKTSGGLHGVGASVVNALSEWLTVTIERDGFVYQQRFENGGKPVTSLEKI GKTKKTGTLTHFKPDPTMFSTTTYNFETLSERLRESAFLLKGLKIELIDERNDQREVF YYENGIEAFVAYLNEEKDVLSEVVSFEGEHHSIEVDFAFQFNDGYSENILSFVNNVRT KDGGTHESGAKTAMTRAFNEYARKVALLKEKDKNLEGTDIREGLSAIISVRIPEELLQ FEGQTKGKLGTSEARSAVDAIVSEQLAYFLEENRDTATLLVKKAIKASQAREAARKAR EEARSGKKRKKSEATLSGKLTPAGSRNPAKNELYLVEGDSAGGSAKQGRDRRFQAVLP LRGKVINTEKAKLADIFKNEEINTIIHAIGGGVGADFSIDDINYDKIIIMTDADTDGA HIQVLLLTFFYRYMKPLIEHGKVFIALPPLYKVSKGSGKKEIIEYAWSDEEMGDVLKK VGKGYTIQRYKGLGEMNADQLWETTMNPESRTLVRVKIDDAARVERRVTTLMGDKVEP RRKWIEKNVAFGLDEESNILENENLSVAEEV*" gene 1933477..1935444 /gene="parE" /locus_tag="BSU_18090" /old_locus_tag="BSU18090" CDS 1935448..1937868 /gene="parC" /locus_tag="BSU_18100" /old_locus_tag="BSU18100" /EC_number="5.99.1.3" /function="16.2: Construct biomass (Anabolism)" /function="16.9: Replicate" /experiment="publication(s) with functional evidences, PMID:9539793, 12682299, 16267290, 16272394, 24440393" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9539793, 12682299, 16267290, 16272394, 24440393; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="subunit A of DNA topoisomerase IV (ATP-dependent)" /protein_id="NP_389692.2" /db_xref="EnsemblGenomes-Gn:BSU18100" /db_xref="EnsemblGenomes-Tr:CAB13693" /db_xref="GOA:Q45066" /db_xref="InterPro:IPR002205" /db_xref="InterPro:IPR005741" /db_xref="InterPro:IPR006691" /db_xref="InterPro:IPR013757" /db_xref="InterPro:IPR013758" /db_xref="InterPro:IPR013760" /db_xref="InterPro:IPR024946" /db_xref="InterPro:IPR035516" /db_xref="SubtiList:BG11803" /db_xref="UniProtKB/Swiss-Prot:Q45066" /translation="MSQPELFHDLPLEEVIGDRFGRYSKYIIQDRALPDARDGLKPVQ RRILYAMHTDGNTFDKNFRKAAKTVGNVIGNYHPHGDSSVYEAMVRMSQDWKVRNVLI EMHGNNGSIDGDPPAAMRYTEARLSPIASELLRDIDKNTVEFVPNFDDTSKEPVVLPA MFPNLLVNGSTGISAGYATDIPPHHLGEVIDAVIKRIQMPSCSVDELMEVIKGPDFPT GGIIQGVDGIRKAYETGKGKIIIRGKAEIETIRGGREQIVITEIPFEVNKANLVKKMD EFRIDKKVEGISEVRDETDRTGLRVVIELKKEADAKGILNFLYKNTDLQITYNFNMVA IHNRRPMLMSLPSILDAYIGHQKEVVTNRSVYELQKAKDRHHIVEGLMKALSILDEVI ATIRSSSDKRDAKNNLIAKYEFTEPQAEAIVSLQLYRLTNTDITALKEEAEELGKKIE ELESILSNDKKLLKVITNSLKALKKKYADTRRSVIEEKIEEIKINLEVMVASEDVYVT VTKDGYLKRTSQRSFAASNGQDFGMKDTDRMLHQFEMNTTDVLLLFTNKGSYIYCPVH QLPDIRWKDMGQHFSNLITIDRDETIVKAIPIKEFDPSAYLLFFTKNGMVKKTELTHY KAQRYSKALVALNLKGEDELIDVHVTNGESQIFMATHLGYGLWFGEDEVNVVGARAAG VKGINLKEDDFVVSGEILQQSDSIVLFTQRGAVKRMSLSEFEKTSRAKRGVVMLRELK KNPHRVVALFACGLEQRLMAETEKGDRKELQTKELRTNDRYSNGSFFFDEEESGKVTA VWRLHTEQ*" gene 1935448..1937868 /gene="parC" /locus_tag="BSU_18100" /old_locus_tag="BSU18100" downshifts 1937848 /Source="Nicolas_upshifts" /id="D991" /incds=0 /nref=227 /ntot=255 /MaxReadThrough="0.556700000000001" /MaxDrop="5.87714" /score="9.15080033" /energy="-14.6" /TU="NA" /idTUdmin="U1465" /TUdmin=0 /isTUend="TRUE" S_feature complement(1937876..1938065) /Source="Nicolas_S_feature" /locus_tag="new_1937876_1938065_c" /HighExp="LPhT, B60, Etha, B36, Gly, LoTm, Sw, BC, S8, Cold" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.99806099999999998" /TUshortSig="SigA, SigA, SigK" /TUshortPSig="0.968, 0.994, 0.642" /TUlongSig="NA" /TUlongPSig="NA" /label="S673" CDS complement(1937915..1938091) /gene="ynfCc" /locus_tag="BSU_18109" /old_locus_tag="BSU18109" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /pseudo /codon_start=1 /transl_table=11 /product="conserved hypothetical protein (C-terminus)" /db_xref="PSEUDO:SOX90559.1" /translation="MFNITRLCNENMRRLLNMLFILRMVILGLFSFTALNLFVWQGIE VIHAVTDLFTNHES*" gene complement(1937915..1938091) /gene="ynfCc" /locus_tag="BSU_18109" /old_locus_tag="BSU18109" /pseudo downshifts complement(1937919) /Source="Nicolas_upshifts" /id="D992" /incds=0 /nref=153 /ntot=267 /MaxReadThrough="0.609599999999999" /MaxDrop="7.72532" /score="38.0779167" /energy="-14.6" /TU="NA" /idTUdmin="U1467" /TUdmin=5 /isTUend="TRUE" CDS complement(1938066..1938476) /gene="ynfCn" /locus_tag="BSU_18110" /old_locus_tag="BSU18110" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /pseudo /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /db_xref="EnsemblGenomes-Gn:BSU18110" /db_xref="EnsemblGenomes-Tr:CAB13694" /db_xref="GOA:Q45067" /db_xref="PSEUDO:CAB13694.1" /db_xref="SubtiList:BG11828" /db_xref="UniProtKB/Swiss-Prot:Q45067" /translation="MDWGIIIKIFSNIKGGGDHLKKVTILKASILFLAIASFHLFSIP HAFDIGHHYKAVADQQEMHEMKAGQNADDEKKSITGAFTLTALWAMAVLLLTAESKST GYSRRRQRKKSFILAKFYQSSYFGKLHVQHHPIM*" gene complement(1938066..1938476) /gene="ynfCn" /locus_tag="BSU_18110" /old_locus_tag="BSU18110" /pseudo promotor_-10 complement(1938449..1938468) /Source="Nicolas_upshift_promotors" /id="U1466" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.83016983016983" /psig="0.968031968031968" /xcortree=410 /SigmaFactorBS="tatttttaaatttaataaatcaGGTTTACTtttaggatggat tgGGGTATTATTATAAAAATATtcagtaatattaaaggagggggagatcatttgaaaa a" /listShort="ynfC, S673" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1938452) /Source="Nicolas_upshifts" /id="U1466" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.83016983016983" /psig="0.968031968031968" /xcortree=410 /SigmaFactorBS="tatttttaaatttaataaatcaGGTTTACTtttaggatggat tgGGGTATTATTATAAAAATATtcagtaatattaaaggagggggagatcatttgaaaa a" /listShort="ynfC, S673" /GFF_Attribute="listLong" promotor_-35 complement(1938483..1938490) /Source="Nicolas_upshift_promotors" /id="U1466" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.83016983016983" /psig="0.968031968031968" /xcortree=410 /SigmaFactorBS="tatttttaaatttaataaatcaGGTTTACTtttaggatggat tgGGGTATTATTATAAAAATATtcagtaatattaaaggagggggagatcatttgaaaa a" /listShort="ynfC, S673" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(1938517..1938536) /Source="Nicolas_upshift_promotors" /id="U1467" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.52947052947053" /psig="0.994005994005994" /xcortree=2729 /SigmaFactorBS="cgctaataaaagaagttttcTCTTTCAAaaataagcaaaaag ATATATACTTAACAAAGTTAaatttatttttaaatttaataaatcaggtttactttta g" /listShort="ynfC, S673" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1938518) /Source="Nicolas_upshifts" /id="U1467" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.52947052947053" /psig="0.994005994005994" /xcortree=2729 /SigmaFactorBS="cgctaataaaagaagttttcTCTTTCAAaaataagcaaaaag ATATATACTTAACAAAGTTAaatttatttttaaatttaataaatcaggtttactttta g" /listShort="ynfC, S673" /GFF_Attribute="listLong" promotor_-35 complement(1938551..1938558) /Source="Nicolas_upshift_promotors" /id="U1467" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.52947052947053" /psig="0.994005994005994" /xcortree=2729 /SigmaFactorBS="cgctaataaaagaagttttcTCTTTCAAaaataagcaaaaag ATATATACTTAACAAAGTTAaatttatttttaaatttaataaatcaggtttactttta g" /listShort="ynfC, S673" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(1938565..1938584) /Source="Nicolas_upshift_promotors" /id="U1468" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.642357642357642" /psig="0.642357642357642" /xcortree=722 /SigmaFactorBS="ctaaacaacatatcatttaaaatatgtttTTATTCACACcat aaaccgggtaTACATACGCTAATAAAAGAAgttttctctttcaaaaataagcaaaaag a" /listShort="ynfC, S673" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1938576) /Source="Nicolas_upshifts" /id="U1468" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.642357642357642" /psig="0.642357642357642" /xcortree=722 /SigmaFactorBS="ctaaacaacatatcatttaaaatatgtttTTATTCACACcat aaaccgggtaTACATACGCTAATAAAAGAAgttttctctttcaaaaataagcaaaaag a" /listShort="ynfC, S673" /GFF_Attribute="listLong" promotor_-35 complement(1938598..1938607) /Source="Nicolas_upshift_promotors" /id="U1468" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.642357642357642" /psig="0.642357642357642" /xcortree=722 /SigmaFactorBS="ctaaacaacatatcatttaaaatatgtttTTATTCACACcat aaaccgggtaTACATACGCTAATAAAAGAAgttttctctttcaaaaataagcaaaaag a" /listShort="ynfC, S673" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1938824..1938829 /Source="Nicolas_upshift_promotors" /id="U1469" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.400599400599401" /psig=1 /xcortree=2601 /SigmaFactorBS="gtaacatctggctatgacaatattcttctcgaaaaaaCTTCC TaattcgtcatatTGTGATATAATAAAACTCGTtatgttaaaaaatctaacatcaaaa t" /listShort="S674, alsT" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1938842..1938861 /Source="Nicolas_upshift_promotors" /id="U1469" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.400599400599401" /psig=1 /xcortree=2601 /SigmaFactorBS="gtaacatctggctatgacaatattcttctcgaaaaaaCTTCC TaattcgtcatatTGTGATATAATAAAACTCGTtatgttaaaaaatctaacatcaaaa t" /listShort="S674, alsT" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1938847 /Source="Nicolas_upshifts" /id="U1469" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.400599400599401" /psig=1 /xcortree=2601 /SigmaFactorBS="gtaacatctggctatgacaatattcttctcgaaaaaaCTTCC TaattcgtcatatTGTGATATAATAAAACTCGTtatgttaaaaaatctaacatcaaaa t" /listShort="S674, alsT" /GFF_Attribute="listLong" S_feature 1938860..1938924 /Source="Nicolas_S_feature" /locus_tag="new_1938860_1938924" /HighExp="Cold, G180, Oxctl, G135, LBGexp, G150, HPh, dia0, Lbexp, LPh" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S674" CDS 1938925..1940322 /gene="alsT" /locus_tag="BSU_18120" /old_locus_tag="BSU18120" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2b: Function from indirect experimental evidences (e.g. phenotypes); PubMedId: 8969507, 12823818, 15849754, 16850406, 22607086; Product type t : transporter" /codon_start=1 /transl_table=11 /product="H+/Na+:nitrogen-donor aminoacid symporter" /protein_id="NP_389694.1" /db_xref="EnsemblGenomes-Gn:BSU18120" /db_xref="EnsemblGenomes-Tr:CAB13695" /db_xref="GOA:Q45068" /db_xref="InterPro:IPR001463" /db_xref="SubtiList:BG11798" /db_xref="UniProtKB/Swiss-Prot:Q45068" /translation="MESFFNSLINIPSDFIWKYLFYILIGLGLFFTIRFGFIQFRYFI EMFRIVGEKPEGNKGVSSMQAFFISAASRVGTGNLTGVALAIATGGPGAVFWMWVVAA VGMASSFVESTLAQLYKVRDGEDFRGGPAYYIQKGLGARWLGIVFAILITVSFGLIFN AVQTNTIAGALDGAFHVNKIVVAIVLAVLTAFIIFGGLKRVVAVSQLIVPVMAGIYIL IALFVVITNITAFPGVIATIVKNALGFEQVVGGGIGGIIVIGAQRGLFSNEAGMGSAP NAAATAHVSHPAKQGFIQTLGVFFDTFIICTSTAFIILLYSVTPKGDGIQVTQAALNH HIGGWAPTFIAVAMFLFAFSSVVGNYYYGETNIEFIKTSKTWLNIYRIAVIAMVVYGS LSGFQIVWDMADLFMGIMALINLIVIALLSNVAYKVYKDYAKQRKQGLDPVFKAKNIP GLKNAETWEDEKQEA*" gene 1938925..1940322 /gene="alsT" /locus_tag="BSU_18120" /old_locus_tag="BSU18120" downshifts 1940311 /Source="Nicolas_upshifts" /id="D993" /incds=0 /nref=112 /ntot=203 /MaxReadThrough="3.44078" /MaxDrop="5.75319" /score="16.664707" /energy="-14.7" /TU="U1469" /idTUdmin="U1469" /TUdmin="-23" /isTUend="FALSE" downshifts 1940356 /Source="Nicolas_upshifts" /id="D994" /incds=0 /nref=1 /ntot=3 /MaxReadThrough="2.22962" /MaxDrop="5.03444" /score="16.664707" /energy="-14.7" /TU="NA" /idTUdmin="U1469" /TUdmin=22 /isTUend="TRUE" S_feature complement(1940412..1941158) /Source="Nicolas_S_feature" /locus_tag="new_1940412_1941158_c" /HighExp="S6, S8, S7, S5, BT, C30, B36, S4, LoTm, B60" /AntisenseName="eglS" /AntisenseCor="0.42607634596628102" /AntisenseRegPval="-12.6" /CDS_PredictionProba="NA" /TUshortSig="SigK" /TUshortPSig="0.997" /TUlongSig="NA" /TUlongPSig="NA" /label="S675" promotor_-35 1940535..1940542 /Source="Nicolas_upshift_promotors" /id="U1470" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.585414585414585" /psig="0.995004995004995" /xcortree=1629 /SigmaFactorBS="ttgacaggcttttaaacctccccaaaacaagaaattaggttG ATAGACAatcatgagaaagATTTTTACAATGAGTTCGTGctcataagaagtgtagagc c" /listShort="eglS" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 1940554 /Source="Nicolas_upshifts" /id="U1470" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.585414585414585" /psig="0.995004995004995" /xcortree=1629 /SigmaFactorBS="ttgacaggcttttaaacctccccaaaacaagaaattaggttG ATAGACAatcatgagaaagATTTTTACAATGAGTTCGTGctcataagaagtgtagagc c" /listShort="eglS" /GFF_Attribute="listLong" promotor_-10 1940555..1940574 /Source="Nicolas_upshift_promotors" /id="U1470" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.585414585414585" /psig="0.995004995004995" /xcortree=1629 /SigmaFactorBS="ttgacaggcttttaaacctccccaaaacaagaaattaggttG ATAGACAatcatgagaaagATTTTTACAATGAGTTCGTGctcataagaagtgtagagc c" /listShort="eglS" /GFF_Attribute="listLong" /label="promotor_-10" CDS 1940625..1942124 /gene="eglS" /locus_tag="BSU_18130" /old_locus_tag="BSU18130" /EC_number="3.2.1.4" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:3024130, 7704256, 7710279, 15139916, 26907762" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 3024130, 7704256, 7710279, 15139916, 26907762; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="endo-1,4-beta-glucanase" /protein_id="NP_389695.2" /db_xref="EnsemblGenomes-Gn:BSU18130" /db_xref="EnsemblGenomes-Tr:CAB13696" /db_xref="GOA:P10475" /db_xref="InterPro:IPR001547" /db_xref="InterPro:IPR001956" /db_xref="InterPro:IPR008965" /db_xref="InterPro:IPR017853" /db_xref="InterPro:IPR018087" /db_xref="InterPro:IPR036966" /db_xref="PDB:2L8A" /db_xref="PDB:3PZT" /db_xref="PDB:3PZU" /db_xref="PDB:3PZV" /db_xref="SubtiList:BG10437" /db_xref="UniProtKB/Swiss-Prot:P10475" /translation="MKRSISIFITCLLITLLTMGGMIASPASAAGTKTPVAKNGQLSI KGTQLVNRDGKAVQLKGISSHGLQWYGEYVNKDSLKWLRDDWGITVFRAAMYTADGGY IDNPSVKNKVKEAVEAAKELGIYVIIDWHILNDGNPNQNKEKAKEFFKEMSSLYGNTP NVIYEIANEPNGDVNWKRDIKPYAEEVISVIRKNDPDNIIIVGTGTWSQDVNDAADDQ LKDANVMYALHFYAGTHGQFLRDKANYALSKGAPIFVTEWGTSDASGNGGVFLDQSRE WLKYLDSKTISWVNWNLSDKQESSSALKPGASKTGGWRLSDLSASGTFVRENILGTKD STKDIPETPSKDKPTQENGISVQYRAGDGSMNSNQIRPQLQIKNNGNTTVDLKDVTAR YWYKAKNKGQNFDCDYAQIGCGNVTHKFVTLHKPKQGADTYLELGFKNGTLAPGASTG NIQLRLHNDDWSNYAQSGDYSFFKSNTFKTTKKITLYDQGKLIWGTEPN*" gene 1940625..1942124 /gene="eglS" /locus_tag="BSU_18130" /old_locus_tag="BSU18130" promotor_-10 complement(1941157..1941176) /Source="Nicolas_upshift_promotors" /id="U1471" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=1389 /SigmaFactorBS="taccggttccgacaatgatgatgttgtctggatcatttttgC GGATAACTGaaatcacttcttcCGCATATGGTTTAATATCACgcttccagttcacatc a" /listShort="S675" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1941180) /Source="Nicolas_upshifts" /id="U1471" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=1389 /SigmaFactorBS="taccggttccgacaatgatgatgttgtctggatcatttttgC GGATAACTGaaatcacttcttcCGCATATGGTTTAATATCACgcttccagttcacatc a" /listShort="S675" /GFF_Attribute="listLong" promotor_-35 complement(1941190..1941199) /Source="Nicolas_upshift_promotors" /id="U1471" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=1389 /SigmaFactorBS="taccggttccgacaatgatgatgttgtctggatcatttttgC GGATAACTGaaatcacttcttcCGCATATGGTTTAATATCACgcttccagttcacatc a" /listShort="S675" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 1942072 /Source="Nicolas_upshifts" /id="D995" /incds=0 /nref=1 /ntot=89 /MaxReadThrough="3.59763" /MaxDrop="3.67571" /score="6.04626297" /energy="-10.7" /TU="NA" /idTUdmin="U1470" /TUdmin=1210 /isTUend="FALSE" CDS 1942192..1942455 /gene="ynfE" /locus_tag="BSU_18140" /old_locus_tag="BSU18140" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_389696.1" /db_xref="EnsemblGenomes-Gn:BSU18140" /db_xref="EnsemblGenomes-Tr:CAB13697" /db_xref="InterPro:IPR020302" /db_xref="SubtiList:BG11829" /db_xref="UniProtKB/Swiss-Prot:Q45069" /translation="MDEILKQYMVLYKKMSNMINGPDYPGKEKDIQHQKDQIEVYEKQ LQQGFSTDYDYDVFADSVIKCAYGDMTLEDLEAVYYGLTTPFF*" gene 1942192..1942455 /gene="ynfE" /locus_tag="BSU_18140" /old_locus_tag="BSU18140" downshifts complement(1942714) /Source="Nicolas_upshifts" /id="D996" /incds=0 /nref=4 /ntot=148 /MaxReadThrough="1.78569" /MaxDrop="4.04338" /score="32.2414244" /energy="-12.6" /TU="NA" /idTUdmin="U1472" /TUdmin=6 /isTUend="TRUE" CDS complement(1942714..1943982) /gene="xynC" /locus_tag="BSU_18150" /old_locus_tag="BSU18150" /EC_number="3.2.1.136" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:17028274, 25355936, 26559526, 28330222" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 17028274, 25355936, 26559526, 28330222; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="secreted endo-xylanase" /protein_id="NP_389697.1" /db_xref="EnsemblGenomes-Gn:BSU18150" /db_xref="EnsemblGenomes-Tr:CAB13698" /db_xref="GOA:Q45070" /db_xref="InterPro:IPR001139" /db_xref="InterPro:IPR017853" /db_xref="InterPro:IPR033452" /db_xref="PDB:3GTN" /db_xref="PDB:3KL0" /db_xref="PDB:3KL3" /db_xref="PDB:3KL5" /db_xref="SubtiList:BG11830" /db_xref="UniProtKB/Swiss-Prot:Q45070" /translation="MIPRIKKTICVLLVCFTMLSVMLGPGATEVLAASDVTVNVSAEK QVIRGFGGMNHPAWAGDLTAAQRETAFGNGQNQLGFSILRIHVDENRNNWYKEVETAK SAVKHGAIVFASPWNPPSDMVETFNRNGDTSAKRLKYNKYAAYAQHLNDFVTFMKNNG VNLYAISVQNEPDYAHEWTWWTPQEILRFMRENAGSINARVIAPESFQYLKNLSDPIL NDPQALANMDILGTHLYGTQVSQFPYPLFKQKGAGKDLWMTEVYYPNSDTNSADRWPE ALDVSQHIHNAMVEGDFQAYVWWYIRRSYGPMKEDGTISKRGYNMAHFSKFVRPGYVR IDATKNPNANVYVSAYKGDNKVVIVAINKSNTGVNQNFVLQNGSASNVSRWITSSSSN LQPGTNLTVSGNHFWAHLPAQSVTTFVVNR*" gene complement(1942714..1943982) /gene="xynC" /locus_tag="BSU_18150" /old_locus_tag="BSU18150" S_feature complement(1943983..1944112) /Source="Nicolas_S_feature" /locus_tag="new_1943983_1944112_c" /HighExp="Lbstat, BC, M0t90, LBGstat, Sw, T2.0H, M40t90, BI, T1.30H, T2.30H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.99419599999999997" /TUshortSig="SigA" /TUshortPSig="0.997" /TUlongSig="NA" /TUlongPSig="NA" /label="S676" CDS complement(1944113..1945654) /gene="xynD" /locus_tag="BSU_18160" /old_locus_tag="BSU18160" /EC_number="3.2.1.55" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:1938968, 17426966, 26559526" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1938968, 17426966, 26559526; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="arabinoxylan arabinofuranohydrolase" /protein_id="NP_389698.1" /db_xref="EnsemblGenomes-Gn:BSU18160" /db_xref="EnsemblGenomes-Tr:CAB13699" /db_xref="GOA:Q45071" /db_xref="InterPro:IPR005084" /db_xref="InterPro:IPR006584" /db_xref="InterPro:IPR006710" /db_xref="InterPro:IPR008979" /db_xref="InterPro:IPR023296" /db_xref="PDB:3C7E" /db_xref="PDB:3C7F" /db_xref="PDB:3C7G" /db_xref="PDB:3C7H" /db_xref="PDB:3C7O" /db_xref="SubtiList:BG11807" /db_xref="UniProtKB/Swiss-Prot:Q45071" /translation="MRKKCSVCLWILVLLLSCLSGKSAYAATSTTIAKHIGNSNPLID HHLGADPVALTYNGRVYIYMSSDDYEYNSNGTIKDNSFANLNRVFVISSADMVNWTDH GAIPVAGANGANGGRGIAKWAGASWAPSIAVKKINGKDKFFLYFANSGGGIGVLTADS PIGPWTDPIGKPLVTPSTPGMSGVVWLFDPAVFVDDDGTGYLYAGGGVPGVSNPTQGQ WANPKTARVIKLGPDMTSVVGSASTIDAPFMFEDSGLHKYNGTYYYSYCINFGGTHPA DKPPGEIGYMTSSSPMGPFTYRGHFLKNPGAFFGGGGNNHHAVFNFKNEWYVVYHAQT VSSALFGAGKGYRSPHINKLVHNADGSIQEVAANYAGVTQISNLNPYNRVEAETFAWN GRILTEKSTAPGGPVNNQHVTSIQNGDWIAVGNADFGAGGARSFKANVASTLGGKIEV RLDSADGKLVGTLNVPSTGGAQTWREIETAVSGATGVHKVFFVFTGTGTGNLFNFDYW QFTQR*" gene complement(1944113..1945654) /gene="xynD" /locus_tag="BSU_18160" /old_locus_tag="BSU18160" S_feature complement(1945655..1945976) /Source="Nicolas_S_feature" /locus_tag="new_1945655_1945976_c" /HighExp="M0t90, LBGstat, T1.30H, T2.30H, BC, M9-stat, T2.0H, T3.0H, T0.30H, Lbstat" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.25588499999999997" /TUshortSig="SigA" /TUshortPSig="0.997" /TUlongSig="NA" /TUlongPSig="NA" /label="S677" promotor_-10 complement(1945966..1945985) /Source="Nicolas_upshift_promotors" /id="U1472" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.568431568431568" /psig="0.997002997002997" /xcortree=563 /SigmaFactorBS="ttgtagaatcgaacactaactcctccaaaagtttCTATacac aatttttttaATGATGTAGGATGTTAGATAaagggatatcttggataatgatgtaatc t" /listShort="S677, xynD, S676, xynC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1945977) /Source="Nicolas_upshifts" /id="U1472" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.568431568431568" /psig="0.997002997002997" /xcortree=563 /SigmaFactorBS="ttgtagaatcgaacactaactcctccaaaagtttCTATacac aatttttttaATGATGTAGGATGTTAGATAaagggatatcttggataatgatgtaatc t" /listShort="S677, xynD, S676, xynC" /GFF_Attribute="listLong" promotor_-35 complement(1946000..1946003) /Source="Nicolas_upshift_promotors" /id="U1472" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.568431568431568" /psig="0.997002997002997" /xcortree=563 /SigmaFactorBS="ttgtagaatcgaacactaactcctccaaaagtttCTATacac aatttttttaATGATGTAGGATGTTAGATAaagggatatcttggataatgatgtaatc t" /listShort="S677, xynD, S676, xynC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1946203..1946210 /Source="Nicolas_upshift_promotors" /id="U1473" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.502497502497502" /psig="0.99000999000999" /xcortree=1619 /SigmaFactorBS="cccgctttttcatgttttgttcatattttattaATTGTTTAt tcaacactgtcCGCTATAGTAATCCATATCAacaaatatgactgccactcgcatcttt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1946223..1946242 /Source="Nicolas_upshift_promotors" /id="U1473" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.502497502497502" /psig="0.99000999000999" /xcortree=1619 /SigmaFactorBS="cccgctttttcatgttttgttcatattttattaATTGTTTAt tcaacactgtcCGCTATAGTAATCCATATCAacaaatatgactgccactcgcatcttt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1946230 /Source="Nicolas_upshifts" /id="U1473" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.502497502497502" /psig="0.99000999000999" /xcortree=1619 /SigmaFactorBS="cccgctttttcatgttttgttcatattttattaATTGTTTAt tcaacactgtcCGCTATAGTAATCCATATCAacaaatatgactgccactcgcatcttt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" CDS 1946249..1946695 /gene="yngA" /locus_tag="BSU_18170" /old_locus_tag="BSU18170" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406, 20512483; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative conserved membrane protein possibly involved in arabinogalactan metabolism" /protein_id="NP_389699.1" /db_xref="EnsemblGenomes-Gn:BSU18170" /db_xref="EnsemblGenomes-Tr:CAB13700" /db_xref="GOA:O31821" /db_xref="InterPro:IPR007267" /db_xref="SubtiList:BG13452" /db_xref="UniProtKB/Swiss-Prot:O31821" /translation="MTATRIFYEGRFVTLKEKIKTLGRFCTVGVGNTLIDFGVFFLLT ACHVSYLPAQICSYTAGIVNSYVWNRNWTFCVKRKADGKEIVRFLMINIAASGITFLL LYLFQNCGCSLLVSKLAATIGGMMMNFIGNRIWVFGDSLKNIQDQE*" gene 1946249..1946695 /gene="yngA" /locus_tag="BSU_18170" /old_locus_tag="BSU18170" CDS 1946702..1947595 /gene="yngB" /locus_tag="BSU_18180" /old_locus_tag="BSU18180" /EC_number="2.7.7.9" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 8320212, 20512483; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative UTP-glucose-1-phosphate uridylyltransferase" /protein_id="NP_389700.1" /db_xref="EnsemblGenomes-Gn:BSU18180" /db_xref="EnsemblGenomes-Tr:CAB13701" /db_xref="GOA:O31822" /db_xref="InterPro:IPR005771" /db_xref="InterPro:IPR005835" /db_xref="InterPro:IPR029044" /db_xref="SubtiList:BG13453" /db_xref="UniProtKB/Swiss-Prot:O31822" /translation="MRKKVRKAVIPAAGLGTRFLPATKAQPKEMLPIVDKPAIQYIVE EAAESGIEDILIITGRNKRSIEDHFDRSAELEFNLREKGKTETLKEMQQIADLANIHY IRQKEPLGLGHAVLCAEHFIGDEPFAVLLGDDIMVSETPALRQLMDVYDVYGTEVVGV QSVLPEDVSKYGIINTSGSQGHVYEVNDLVEKPSPEEAPSEIAVMGRYVLNSSIFSVL KTIGRGAGNEIQLTDALREVCRKEPIHARLLEGNRYDIGDKLGCFKASTEIGLMRPEM RSQLLAYLEDVIKRETKEMLR*" gene 1946702..1947595 /gene="yngB" /locus_tag="BSU_18180" /old_locus_tag="BSU18180" misc_feature 1947212..1947231 /Source="Nicolas_upshift_promotors" /id="U1474" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.997002997002997" /psig=1 /xcortree=2146 /SigmaFactorBS="tggcacagaggttgtcggtgtacagtcagttctccctgagga tgtcagcaaaTATGGTATTATAAATACATCagggtctcaagggcatgtatatgaagtg a" /listShort="yngC" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 1947220 /Source="Nicolas_upshifts" /id="U1474" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.997002997002997" /psig=1 /xcortree=2146 /SigmaFactorBS="tggcacagaggttgtcggtgtacagtcagttctccctgagga tgtcagcaaaTATGGTATTATAAATACATCagggtctcaagggcatgtatatgaagtg a" /listShort="yngC" /GFF_Attribute="listLong" CDS 1947668..1948264 /gene="yngC" /locus_tag="BSU_18190" /old_locus_tag="BSU18190" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406, 20512483; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative integral inner membrane protein, phosphatase or phosphate isomerase" /protein_id="NP_389701.1" /db_xref="EnsemblGenomes-Gn:BSU18190" /db_xref="EnsemblGenomes-Tr:CAB13702" /db_xref="GOA:O31823" /db_xref="InterPro:IPR032816" /db_xref="SubtiList:BG13454" /db_xref="UniProtKB/Swiss-Prot:O31823" /translation="MGSLISEILTWLTNMGYAGIAIGLMIEIIPSEIVLAYGGYMVSE GTIGFIGAIIAGVIGGTIAQIFIYWIGRYGGRPFLDKYGKYLLIKKHHIDMSENWFQK YGAGVVFSARFIPVVRHAISIPAGIARMPFLKFVVLTVLAIIPWSILFVYLGIQLGSQ WDDVENIAGTYTTPIMILAVVVIALYFVIKKRTAIFKR*" gene 1947668..1948264 /gene="yngC" /locus_tag="BSU_18190" /old_locus_tag="BSU18190" downshifts 1948254 /Source="Nicolas_upshifts" /id="D997" /incds=0 /nref=191 /ntot=259 /MaxReadThrough="1.94273" /MaxDrop="5.58345" /score="15.4353025" /energy="-15" /TU="NA" /idTUdmin="U1474" /TUdmin=0 /isTUend="TRUE" CDS complement(1948313..1949512) /gene="nrnB" /locus_tag="BSU_18200" /old_locus_tag="BSU18200" /function="16.11: Scavenge (Catabolism)" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:19553197, 22262096" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 19553197, 22262096; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="oligoribonuclease (nanoRNase)" /protein_id="NP_389702.1" /db_xref="EnsemblGenomes-Gn:BSU18200" /db_xref="EnsemblGenomes-Tr:CAB13703" /db_xref="GOA:O31824" /db_xref="SubtiList:BG13455" /db_xref="UniProtKB/Swiss-Prot:O31824" /translation="MYHLYSHNDLDGVGCGIVAKLAFGKDVEIRYNSVNGLNAQVQYF LEKAKESNRQDALFITDLAVNEENEERLNEYVHAGGKVKLIDHHKTALHLNEHEWGFV QVEYDDGRLTSATSLLYGYLIENGFMKPTNALDQFTELVRQYDTWEWERYDQKQAKRL NDLFFLLSIDEFEAKMIQRLSTHDEFFFDDFEEKLLDLEDEKIERYLRRKKREMVQTF VHEHCVGIVHAESYHSELGNRLGKDNPHLDYIAILSMGSKRVSLRTIHDYIDVSEIAG RYGGGGHAKASGCSITDEVYELFVAEAFRIDPVRPDAFRNIYNLKGSANGSLYENRAQ MRFFLFPLDNEWNIQINGETQDETFAAFEEAEWFIKRNYAASLVRDEVFVAFLAENLK LANQHRK*" gene complement(1948313..1949512) /gene="nrnB" /locus_tag="BSU_18200" /old_locus_tag="BSU18200" S_feature complement(1949513..1949584) /Source="Nicolas_S_feature" /locus_tag="new_1949513_1949584_c" /HighExp="S5, S7, S4, S8, S6, ferm, nit, LBGstat, T5.0H, S3" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigGF" /TUshortPSig="0.977" /TUlongSig="NA" /TUlongPSig="NA" /label="S678" promotor_-10 complement(1949572..1949583) /Source="Nicolas_upshift_promotors" /id="U1475" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.977022977022977" /psig="0.977022977022977" /xcortree=933 /SigmaFactorBS="atatatttacaataacaacattatgtcaactaattaccatTG CATAAaacgcttggtttttTAGAATAGTAAAtaaaggctgccgcacctctagcggcaa t" /listShort="S678, yngD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1949584) /Source="Nicolas_upshifts" /id="U1475" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.977022977022977" /psig="0.977022977022977" /xcortree=933 /SigmaFactorBS="atatatttacaataacaacattatgtcaactaattaccatTG CATAAaacgcttggtttttTAGAATAGTAAAtaaaggctgccgcacctctagcggcaa t" /listShort="S678, yngD" /GFF_Attribute="listLong" promotor_-35 complement(1949598..1949604) /Source="Nicolas_upshift_promotors" /id="U1475" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.977022977022977" /psig="0.977022977022977" /xcortree=933 /SigmaFactorBS="atatatttacaataacaacattatgtcaactaattaccatTG CATAAaacgcttggtttttTAGAATAGTAAAtaaaggctgccgcacctctagcggcaa t" /listShort="S678, yngD" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(1949682..1951217) /gene="ldeE" /locus_tag="BSU_18210" /old_locus_tag="BSU18210" /EC_number="6.4.1.4" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2b: Function from indirect experimental evidences (e.g. phenotypes); PubMedId: 19935659; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="methylcrotonoyl-CoA carboxylase subunit (leucinedegradation)" /protein_id="NP_389703.2" /db_xref="EnsemblGenomes-Gn:BSU18210" /db_xref="EnsemblGenomes-Tr:CAB13704" /db_xref="GOA:O31825" /db_xref="InterPro:IPR011762" /db_xref="InterPro:IPR011763" /db_xref="InterPro:IPR029045" /db_xref="InterPro:IPR034733" /db_xref="SubtiList:BG13456" /db_xref="UniProtKB/Swiss-Prot:O31825" /translation="MLMDYEKERTERAERIRKGGAEKYHQSNREKGKLFVRERLSLLF DDDIELEDAFFAECMSDGLPADGVVTAIGKIGGQTVCVMANDSTVKAGSWGAKTVEKI IRIQEIAEKLNCPLIYLVDSAGARITDQINVFPGRRGAGRIFYNQVKLSGRIPQICLL FGPSAAGGAYIPAFCDIVVMVDGNASMYLGSPRMAEMVIGEKVSLEEMGGARMHCSIS GCGDILAETEEEAIQLVRAYLSYFPANFQEKAPIHEKRPPKHFETPLADVIPQNQNAP FDMHELIERVIDEDSFFEIKALFAPELLTGLARIHGQPVGIVANQPKVKGGVLFHDSA DKAAKFITLCDAFHIPLLFLADIPGFMIGTKVEQAGIIRHGAKMISAMSEATVPKLSV IVRKAYGAGLYAMAGPAFEPDCCLALPTAQIAVMGPEAAVNAVYAKKIAELPEEERAA FISSKREEYKEDINIYRLASEMIIDAVIPANSLRDELAKRLKAYMTKEMTFTNRKHPV YPV*" gene complement(1949682..1951217) /gene="ldeE" /locus_tag="BSU_18210" /old_locus_tag="BSU18210" downshifts complement(1949694) /Source="Nicolas_upshifts" /id="D998" /incds=0 /nref=18 /ntot=38 /MaxReadThrough="1.74923" /MaxDrop="5.31437" /score="-1.4478995" /energy="-11.8" /TU="NA" /idTUdmin="U1477" /TUdmin=0 /isTUend="TRUE" CDS complement(1951228..1952010) /gene="ldeF" /locus_tag="BSU_18220" /old_locus_tag="BSU18220" /EC_number="4.2.1.18" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2b: Function from indirect experimental evidences (e.g. phenotypes); PubMedId: 19935659; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="methylglutaconyl-CoA hydratase (leucine degradation)" /protein_id="NP_389704.1" /db_xref="EnsemblGenomes-Gn:BSU18220" /db_xref="EnsemblGenomes-Tr:CAB13705" /db_xref="GOA:O34893" /db_xref="InterPro:IPR001753" /db_xref="InterPro:IPR014748" /db_xref="InterPro:IPR018376" /db_xref="InterPro:IPR029045" /db_xref="SubtiList:BG13457" /db_xref="UniProtKB/Swiss-Prot:O34893" /translation="MGDSILFTVKNEHMALITLNRPQAANALSAEMLRNLQMIIQEIE FNSNIRCVILTGTGEKAFCAGADLKERIKLKEDQVLESVSLIQRTAALLDALPQPVIA AINGSALGGGLELALACDLRIATEAAVLGLPETGLAIIPGAGGTQRLPRLIGRGKAKE FIYTGRRVTAHEAKEIGLVEHVTAPCDLMPKAEELAAAISANGPIAVRQAKFAINKGL ETDLATGLAIEQKAYEQTIPTKDRREGLQAFQEKRRAVYKGI*" gene complement(1951228..1952010) /gene="ldeF" /locus_tag="BSU_18220" /old_locus_tag="BSU18220" CDS complement(1952031..1952930) /gene="ldeG" /locus_tag="BSU_18230" /old_locus_tag="BSU18230" /EC_number="4.1.3.4" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2b: Function from indirect experimental evidences (e.g. phenotypes); PubMedId: 16330546, 19935659, 22720735; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="hydroxymethylglutaryl-CoA lyase (leucine degradation)" /protein_id="NP_389705.1" /db_xref="EnsemblGenomes-Gn:BSU18230" /db_xref="EnsemblGenomes-Tr:CAB13706" /db_xref="GOA:O34873" /db_xref="InterPro:IPR000891" /db_xref="InterPro:IPR013785" /db_xref="PDB:1YDO" /db_xref="SubtiList:BG13458" /db_xref="UniProtKB/Swiss-Prot:O34873" /translation="MPYPKKVTIKEVGPRDGLQNEPVWIATEDKITWINQLSRTGLSY IEITSFVHPKWIPALRDAIDVAKGIDREKGVTYAALVPNQRGLENALEGGINEACVFM SASETHNRKNINKSTSESLHILKQVNNDAQKANLTTRAYLSTVFGCPYEKDVPIEQVI RLSEALFEFGISELSLGDTIGAANPAQVETVLEALLARFPANQIALHFHDTRGTALAN MVTALQMGITVFDGSAGGLGGCPYAPGSSGNAATEDIVYMLEQMDIKTNVKLEKLLSA AKWIEEKMGKPLPSRNLQVFKSS*" gene complement(1952031..1952930) /gene="ldeG" /locus_tag="BSU_18230" /old_locus_tag="BSU18230" CDS complement(1952945..1953166) /gene="lgeHB" /locus_tag="BSU_18239" /old_locus_tag="BSU18239" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1a: Function from experimental evidences in the studied strain; Product type c: carrier" /codon_start=1 /transl_table=11 /product="methylcrotonyl-CoA carboxylase; biotinylated subunit (leucine degradation)" /protein_id="YP_003097733.1" /db_xref="EnsemblGenomes-Gn:BSU18239" /db_xref="EnsemblGenomes-Tr:CAX52627" /db_xref="InterPro:IPR000089" /db_xref="InterPro:IPR011053" /db_xref="PDB:1Z6H" /db_xref="PDB:1Z7T" /db_xref="PDB:2B8F" /db_xref="PDB:2B8G" /db_xref="UniProtKB/Swiss-Prot:C0H419" /translation="MTVSIQMAGNLWKVHVKAGDQIEKGQEVAILESMKMEIPIVADR SGIVKEVKKKEGDFVNEGDVLLELSNSTQ*" gene complement(1952945..1953166) /gene="lgeHB" /locus_tag="BSU_18239" /old_locus_tag="BSU18239" CDS complement(1953181..1954515) /gene="ldeHA" /locus_tag="BSU_18240" /old_locus_tag="BSU18240" /EC_number="6.4.1.4" /EC_number="6.3.4.14" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2b: Function from indirect experimental evidences (e.g. phenotypes); PubMedId: 7915138, 19935659; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="biotin carboxylase for subunit LdeHB of methylcrotonyl-CoA carboxylase" /protein_id="NP_389706.1" /db_xref="EnsemblGenomes-Gn:BSU18240" /db_xref="EnsemblGenomes-Tr:CAB13707" /db_xref="GOA:O34544" /db_xref="InterPro:IPR005479" /db_xref="InterPro:IPR005481" /db_xref="InterPro:IPR005482" /db_xref="InterPro:IPR011054" /db_xref="InterPro:IPR011761" /db_xref="InterPro:IPR011764" /db_xref="InterPro:IPR013815" /db_xref="InterPro:IPR016185" /db_xref="SubtiList:BG13459" /db_xref="UniProtKB/Swiss-Prot:O34544" /translation="MFTKVLIANRGEIAMRIIRTCSRLGIKTVAVYSEADKDAPHTKA ATEAYLIGESRVSESYLNIERIIKTAKKAKADAIHPGYGLLSENSRFAERCKQENIVF IGPSPDIIAKMGSKIEARKAMEAAGVPVVPGVSESLGDIEAACRTASQIGYPVMLKAS AGGGGIGMQRVENEEALKKAYEGNKKRAADFFGDGSMYIEKVIEHARHIEVQLLADQH GHTVHLFERDCSVQRRHQKVIEEAPSPFVDDELRMKIGQTAVKAAKAIGYTNAGTIEF IVDQKQNFYFLEMNTRLQVEHPVTEEITGLDLVEQQLRIAAGHTLTFSQKDIQRNGHA IEVRIYAEDPKTFFPSPGTITAFSLPDQKGVRHECAVAKDSTVTPFYDPMIAKMIVKG QTRTEAIEKLETALRDYRVEGIKTNLPLLIQAAATKAFKEGDVTTDFLKQHL*" gene complement(1953181..1954515) /gene="ldeHA" /locus_tag="BSU_18240" /old_locus_tag="BSU18240" CDS complement(1954525..1956174) /gene="ldeI" /locus_tag="BSU_18250" /old_locus_tag="BSU18250" /EC_number="6.2.1.16" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2b: Function from indirect experimental evidences (e.g. phenotypes); PubMedId: 12535077, 15213221, 19935659; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="acetoacetyl-CoA synthetase" /protein_id="NP_389707.1" /db_xref="EnsemblGenomes-Gn:BSU18250" /db_xref="EnsemblGenomes-Tr:CAB13708" /db_xref="GOA:O31826" /db_xref="InterPro:IPR000873" /db_xref="InterPro:IPR020845" /db_xref="InterPro:IPR025110" /db_xref="SubtiList:BG13460" /db_xref="UniProtKB/Swiss-Prot:O31826" /translation="MAELIHSTIGRLLEQTADAYPDRDAVVYPDRNIRYTYAQFDSLC RQTAKGLMRMGIGKGDHVAIWASNISEWLAVQFATAKIGAVLVTVNTNYQAHELDYLL KQSDAAALIIMDSYRGTSYPDIVNSLIPELQEAKPGQLKSERYPFLKTLIYIGNKRLS GMYHWDDTEILAKTVTDAELEERMNSLDKDNVINMQYTSGTTGFPKGVMLTHFNVINN AANIAECMALTSQDRMCIPVPFFHCFGCVLGVLACVSVGAAMIPVQEFDPVTVLKTVE KEKCTVLHGVPTMFIAELHHPDFDAYDLSTLRTGIMAGSPCPSEVMKAVIERMGMKDI TIAYGQTEASPVITQTRANDSFIRRVETTGRALPHTEVKIVEPGTCQEVQRGMQGELC TRGYHVMKGYYKDKDATRKAINHDGWLFTGDLAVMDEDGYCRITGRLKDMLIRGGENI YPREIEEFLYQHPAVLDVQVVGVPDAKFGEEAAAWIKLKDGKSVSPDELKAYCKGKIA RHKIPRYVIFTDDYPMTASGKIQKYKLREKTIEMFNLSSSQ*" gene complement(1954525..1956174) /gene="ldeI" /locus_tag="BSU_18250" /old_locus_tag="BSU18250" promotor_no_box 1954574..1954674 /Source="Nicolas_upshift_promotors" /id="U1476" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.287712287712288" /psig="0.174825174825175" /xcortree=1695 /SigmaFactorBS="ttatatttttgaattttgcctgaggccgtcatcggatagtca tccgtaaaaataacataacgcggaattttgtggcgggcgattttccctttgcaatagg c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_no_box" upshifts 1954634 /Source="Nicolas_upshifts" /id="U1476" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.287712287712288" /psig="0.174825174825175" /xcortree=1695 /SigmaFactorBS="ttatatttttgaattttgcctgaggccgtcatcggatagtca tccgtaaaaataacataacgcggaattttgtggcgggcgattttccctttgcaatagg c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" CDS complement(1956218..1957360) /gene="ldeJ" /locus_tag="BSU_18260" /old_locus_tag="BSU18260" /EC_number="1.3.8.4" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2b: Function from indirect experimental evidences (e.g. phenotypes); PubMedId: 8655474, 17085570, 19935659; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="isovaleryl-CoA dehydrogenase (leucine degradation)" /protein_id="NP_389708.1" /db_xref="EnsemblGenomes-Gn:BSU18260" /db_xref="EnsemblGenomes-Tr:CAB13709" /db_xref="GOA:O34421" /db_xref="InterPro:IPR006089" /db_xref="InterPro:IPR006091" /db_xref="InterPro:IPR009075" /db_xref="InterPro:IPR009100" /db_xref="InterPro:IPR013786" /db_xref="InterPro:IPR036250" /db_xref="InterPro:IPR037069" /db_xref="SubtiList:BG13461" /db_xref="UniProtKB/Swiss-Prot:O34421" /translation="MNFELTKEQQMVREMVKDFAKKEIAPHAEHVDQTGEFPMQTFKK MGELGLMGIPFPEEYGGSGGDTISYALAVEEVGKACGSTGLSYAAAVSLGASPLYYFG TEEQKQTHLTPLASGTALGSFGLTEPNAGSDAGGTQTKAISNGDEYVINGEKCWITNA SYARTVIVTAVTGKNKDGKNIISALIVPTDTPGLTITSPYDKMGVRGSNTAEILLEDV RVPAANLLGDPTKGFKQFLYTLDGGRISIAALAVGIAQAALDASLAYAKERKQFGQPI SSFQAIQFKLADMAMEIDLARQMVLKAAWLKDHNRPFTKEAAYAKLFASEMATRACNQ AIQIHGGSGYMKEYGVERMLRDAKLMEIGEGTSEIQRLVIARQLLK*" gene complement(1956218..1957360) /gene="ldeJ" /locus_tag="BSU_18260" /old_locus_tag="BSU18260" promotor_-10 complement(1957379..1957397) /Source="Nicolas_upshift_promotors" /id="U1477" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1156 /SigmaFactorBS="aaatgattcagttttaattttcagacttttcttgtcagGGAA TGattatagaactcgccTAATAGGATGTTACAAAGAtgtgaaggaggaaacgatgtga a" /listShort="yngJ, yngI, yngHA, yngHB, yngG, yngF, yngE" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1957396) /Source="Nicolas_upshifts" /id="U1477" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1156 /SigmaFactorBS="aaatgattcagttttaattttcagacttttcttgtcagGGAA TGattatagaactcgccTAATAGGATGTTACAAAGAtgtgaaggaggaaacgatgtga a" /listShort="yngJ, yngI, yngHA, yngHB, yngG, yngF, yngE" /GFF_Attribute="listLong" promotor_-35 complement(1957413..1957418) /Source="Nicolas_upshift_promotors" /id="U1477" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1156 /SigmaFactorBS="aaatgattcagttttaattttcagacttttcttgtcagGGAA TGattatagaactcgccTAATAGGATGTTACAAAGAtgtgaaggaggaaacgatgtga a" /listShort="yngJ, yngI, yngHA, yngHB, yngG, yngF, yngE" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(1957451..1957756) /gene="ynzE" /locus_tag="BSU_18270" /old_locus_tag="BSU18270" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_389709.1" /db_xref="EnsemblGenomes-Gn:BSU18270" /db_xref="EnsemblGenomes-Tr:CAB13710" /db_xref="GOA:O34356" /db_xref="InterPro:IPR020509" /db_xref="SubtiList:BG13468" /db_xref="UniProtKB/Swiss-Prot:O34356" /translation="MLTDPAEEAFLPNFLLLGAGTALVLCLVFFLYQKLDQSQFAVIK LGIWGSAVGLLMDTISLWNLPLIFPALSKGQVIAFTIWMVCAYCMYLLIPLILSHKK* " gene complement(1957451..1957756) /gene="ynzE" /locus_tag="BSU_18270" /old_locus_tag="BSU18270" CDS complement(1957746..1957919) /locus_tag="BSU_18275" /old_locus_tag="BSU18275" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="YP_009513961.1" /translation="MNMEAVFGHLPLLESEKLVLNKNKIEEKHVQDVFYVFISSLVRC HIIFCAVRRCCVD*" gene complement(1957746..1957919) /locus_tag="BSU_18275" /old_locus_tag="BSU18275" CDS complement(1958027..1959559) /gene="yngK" /locus_tag="BSU_18280" /old_locus_tag="BSU18280" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 10960106; Product type s: structure" /codon_start=1 /transl_table=11 /product="putative exported glycoside hydrolase" /protein_id="NP_389710.1" /db_xref="EnsemblGenomes-Gn:BSU18280" /db_xref="EnsemblGenomes-Tr:CAB13711" /db_xref="InterPro:IPR003790" /db_xref="InterPro:IPR013783" /db_xref="InterPro:IPR017853" /db_xref="SubtiList:BG13462" /db_xref="UniProtKB/Swiss-Prot:O35015" /translation="MKVCQKSIVRFLVSLIIGTFVISVPFMANAQSDRELRAVWIASV LNIDWPSKKGLSVKEQKQEYIKLLDDVQKMGMNAVIVQIKPTADAFYPSAYGPWSEYL TGVQGKDPGYDPLAFMIEETHKRNLEFHAWFNPYRITMNHTDLNKLSEDHPARKHPDW VAAYGNQLYYHPGIPEARDFIVKGIEEVVKHYDIDAVHMDDYFYPYKIAGQEFPDQAQ YEQYGKDAFSNIDDWRRDNVNQLVKQINQTIKAAKPYVKFGISPFGVWRNAADDPTGS NTKAGVRNYDDLYADTRHWIQEGDIDYIAPQIYWSIGFNAAAYDVLADWWSNEVKNRP VHLYIGQAAYKINNNFDPPWSDPEEYVRQITLNRQLELVKGSMHFSLKDLNKNPLGIK DSLSTDLYSKPALVPQMPWLDNTAPKKPKLTKVTEDKNGNLLQIKDHPSNQKTKETAY YAIYRAEGKKQRTLLATQRKTHEQQTFLDNTADPNKKYTYYVTSADRLHNESKASKRT TK*" gene complement(1958027..1959559) /gene="yngK" /locus_tag="BSU_18280" /old_locus_tag="BSU18280" downshifts complement(1958038) /Source="Nicolas_upshifts" /id="D999" /incds=0 /nref=7 /ntot=27 /MaxReadThrough="2.27934" /MaxDrop="4.41371" /score="9.43133612" /energy="-8" /TU="NA" /idTUdmin="U1478" /TUdmin="-6" /isTUend="TRUE" promotor_-10 complement(1959594..1959613) /Source="Nicolas_upshift_promotors" /id="U1478" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp="0.995004995004995" /psig="0.995004995004995" /xcortree=1335 /SigmaFactorBS="tagtgagatagacattctgTTAATCACCCttttatagcccgG GAATACCGTAATAGCGAATagtgaaagtgatgtaatgggggagaagaaacagaatgaa g" /listShort="yngK" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1959594) /Source="Nicolas_upshifts" /id="U1478" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp="0.995004995004995" /psig="0.995004995004995" /xcortree=1335 /SigmaFactorBS="tagtgagatagacattctgTTAATCACCCttttatagcccgG GAATACCGTAATAGCGAATagtgaaagtgatgtaatgggggagaagaaacagaatgaa g" /listShort="yngK" /GFF_Attribute="listLong" promotor_-35 complement(1959626..1959635) /Source="Nicolas_upshift_promotors" /id="U1478" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp="0.995004995004995" /psig="0.995004995004995" /xcortree=1335 /SigmaFactorBS="tagtgagatagacattctgTTAATCACCCttttatagcccgG GAATACCGTAATAGCGAATagtgaaagtgatgtaatgggggagaagaaacagaatgaa g" /listShort="yngK" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(1959695..1960087) /gene="yngL" /locus_tag="BSU_18290" /old_locus_tag="BSU18290" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406, 22720735, 28163698; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative integral inner membrane protein" /protein_id="NP_389711.1" /db_xref="EnsemblGenomes-Gn:BSU18290" /db_xref="EnsemblGenomes-Tr:CAB13712" /db_xref="GOA:O34506" /db_xref="InterPro:IPR010773" /db_xref="SubtiList:BG13463" /db_xref="UniProtKB/Swiss-Prot:O34506" /translation="MDRLSFLTFIMLILASYRLTHLIVFDKITEFIRKPFMKKKRIVD QNGHVDEKSVPASNFGYMLNCYWCAGVWCAILIGLGYLFLPRIAIPLIFILAIAGAQA ILETAVGVGVKLIDVLKSLQTMMNDKKS*" gene complement(1959695..1960087) /gene="yngL" /locus_tag="BSU_18290" /old_locus_tag="BSU18290" downshifts complement(1959726) /Source="Nicolas_upshifts" /id="D1000" /incds=0 /nref=2 /ntot=18 /MaxReadThrough="0.581539999999999" /MaxDrop="2.96298" /score="5.25915686" /energy="-11.4" /TU="NA" /idTUdmin="U1479" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(1960115..1960126) /Source="Nicolas_upshift_promotors" /id="U1479" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=852 /SigmaFactorBS="agaggccattctctgtccgtctttctttttgtatcaAGAATG GataagggacacttGGGAATGATAACatcatcctttttcttggaggcttctcaatgga c" /listShort="yngL" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1960122) /Source="Nicolas_upshifts" /id="U1479" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=852 /SigmaFactorBS="agaggccattctctgtccgtctttctttttgtatcaAGAATG GataagggacacttGGGAATGATAACatcatcctttttcttggaggcttctcaatgga c" /listShort="yngL" /GFF_Attribute="listLong" promotor_-35 complement(1960140..1960146) /Source="Nicolas_upshift_promotors" /id="U1479" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=852 /SigmaFactorBS="agaggccattctctgtccgtctttctttttgtatcaAGAATG GataagggacacttGGGAATGATAACatcatcctttttcttggaggcttctcaatgga c" /listShort="yngL" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(1960198..1964037) /gene="ppsE" /locus_tag="BSU_18300" /old_locus_tag="BSU18300" /EC_number="2.3.1.-" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:9889147, 10471562, 12486459, 22720735, 26284661" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9889147, 10471562, 12486459, 22720735, 26284661; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="nonribosomal plipastatin synthetase E" /protein_id="NP_389712.1" /db_xref="EnsemblGenomes-Gn:BSU18300" /db_xref="EnsemblGenomes-Tr:CAB13713" /db_xref="GOA:O31827" /db_xref="InterPro:IPR000873" /db_xref="InterPro:IPR001031" /db_xref="InterPro:IPR001242" /db_xref="InterPro:IPR006162" /db_xref="InterPro:IPR009081" /db_xref="InterPro:IPR010071" /db_xref="InterPro:IPR020459" /db_xref="InterPro:IPR020802" /db_xref="InterPro:IPR020806" /db_xref="InterPro:IPR020845" /db_xref="InterPro:IPR025110" /db_xref="InterPro:IPR029058" /db_xref="InterPro:IPR036736" /db_xref="SubtiList:BG11962" /db_xref="UniProtKB/Swiss-Prot:O31827" /translation="MKKGADTMNTIKKIKNIYPLSHMQEGMLFHSFLRKEEGAYVEQS LFTIKGSLSYDWFQRSIQAIIDRHDIFRTVFLPHVPHLSGPRQVVMTEREFHLNSEDI SHLPTNDQNEYIERFKEKDKQKGFDLQKDMLMRISLFKTAKDEHVCIWSHHHILMDGW CLGIVMQEFMQIYQSIHAGKPLSLDPVRPYSTYISWLTNRDKEKAAAYWDTYLKNYSA PSPLPRVSDKETKESYHREDLIFSLNKPLTDKLKETAKQHGVTLATLIQAVWGVMLQQ YNRTDDVVFGAVVSGRPSEIPGVEQMIGLFINTIPIRIKTHQDETFHELLIRCQKEML EAEPFTCQPLFDIQANTALKQELIDHIIVFENYPLQQKIADSADQTDSPLQIDQVQVS EQSGYNFNLVVAPGEELVIKFSYNAFVYDAAWISCIKRQFTQALSTAAQHPHMPIADF SFLDATEKEQIVTQFNNTKTEYPKNHTIIDLFREQAEKTPDHTALVYGNMSISYKELD KRSNALARELIQKGFRKNETAGILAAHSPEFMISVLAVLKAGGAYLPLDAELPPERVS FMLEETQAKMLIVQKGLEQNAAFSGTCIISDAQGLMEENDIPINISSSPDDLAYIMYT SGSTGRPKGVMITNRNVVSLVRNSNYTSASGDDRFIMTGSISFDAVTFEMFGALLNGA SLHIIDKSTMLTPDRFGAYLLENDITVLFLTTALFNQLAQVRADMFRGLHTLYVGGEA LSPALMNAVRHACPDLALHNIYGPTENTTFSTFFEMKRDYAGPIPIGKPISNSTAYIL DTKGRLLPIGVPGELCVGGDGVAKGYLNRVDLTNAVFSPHPFLPGERIYRTGDLARWL PDGNLEYISRIDRQMKIRGKRIEPAEIEARLLEMEGVQEAAVTLREKDGEAQLYTHYV GDHKKTDTDFRADLARVLPDYMIPQHWVRVERMPLTGNGKIDRSALPIPENKPAKRQN IILPRNLVEEELANIWKQVLGVNTISIDDDFFAIGGHSLRALQVIHTLKHQQNIDIPI DFLFEHPTIAQLAEKLYSKQLTAANEQHVIKLNQHGAQNLFCFPPISGFGIYFKDLAL LLNEKAAVYGFHFIEQDTRIEQYVNCMTDIQPEGPYVLLGYSAGGNLAFEVAQAMERK GLEVSDFIIVDAYLKEQPLPIDTGNDESAAYLPEAVREKVMKKKRNYQEYWAQLLNEG HIKASIHFIEAGIHPETSGHTGLTKWEGACGNYSEYTGFGAHKDMLEGTYAEKNADII LDILEKITSNQVILHKR*" gene complement(1960198..1964037) /gene="ppsE" /locus_tag="BSU_18300" /old_locus_tag="BSU18300" downshifts complement(1960210) /Source="Nicolas_upshifts" /id="D1001" /incds=0 /nref=51 /ntot=190 /MaxReadThrough="0.85603" /MaxDrop="4.50208" /score="20.3407616" /energy="-16.7" /TU="NA" /idTUdmin="U1479" /TUdmin="-484" /isTUend="FALSE" CDS complement(1964045..1974856) /gene="ppsD" /locus_tag="BSU_18310" /old_locus_tag="BSU18310" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:9889147, 10471562, 16707694, 26284661, 28477175" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9889147, 10471562, 16707694, 26284661, 28477175; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="nonribosomal plipastatin synthetase D involved in synthesis of plipastatin" /protein_id="NP_389713.2" /db_xref="EnsemblGenomes-Gn:BSU18310" /db_xref="EnsemblGenomes-Tr:CAB13714" /db_xref="GOA:P94459" /db_xref="InterPro:IPR000873" /db_xref="InterPro:IPR001242" /db_xref="InterPro:IPR006162" /db_xref="InterPro:IPR009081" /db_xref="InterPro:IPR010060" /db_xref="InterPro:IPR010071" /db_xref="InterPro:IPR013321" /db_xref="InterPro:IPR020806" /db_xref="InterPro:IPR020845" /db_xref="InterPro:IPR025110" /db_xref="InterPro:IPR036736" /db_xref="SubtiList:BG11961" /db_xref="UniProtKB/Swiss-Prot:P94459" /translation="MTKANSIQDIYPLSYMQEGMLFHSLLQKDSQAYVEQASFTIEGK VNPQFFQNSINALVERHDIFRTIFISQNVSSPQQVVLRERNVIVLEEDITHLNEAEQS QFIEQWKEKDRDRGFHLQKDVLMRIALIQTGESQYSCIWTFHHIMMDGWCLSIVLKEF LHIYASYVNASPITLEPVQPYGKYIKWLMEQDKEQAVSYWDHYLSGHEQQTVLPKQKK TKGKSRQEHVTFSFSKEESSRLSELAAREEVTLSTIFHTIWGILLQKYNNNDDAVFGS VISGRPAEIEGIEHMVGLFINTMPVRVQGAKTPFLQLIKDMQKDRLAAEAYSYHPLYE IQSRSAVKQGLIDHILVFENYPVQQEIQMLNKQEHASDLFQIHNFTVADETNYSFYLM VAPGEEIHIKMNYDAEQHDRSFVLSVKEHLLNAVSQILNNPNLPPEEIDITTDTEKRQ LIGEITDQTPVYETIHAMFEKQAEKTPDAHAVIDQACSLTYRELNKAANRLARHLRMK GVVRQEPVAIMMERSAAFITGVLGILKAGGAIVPVDPHYPADRIRYILHDCGCSHVVS QAHLPSSLEDNYIITHPEDIESKVDGSNIKSVNNADDLLYMIYTSGTTGKPKGVQFEH RNMANLLKFEYTHSGIDFEADVLQFATPSFDVCYQEIFSALLKGGTLHIVPEAIKRDV PQLFAFINKHQTNIVFLPTAFIKMIFSERELANSFPDGVKHLIAAGEQLMISDLFQDV LRKRGIHLHNHYGPSETHVVSTYTIHPGDPIPELPPIGKPIGCTDLYILNHQKQLQPC GVPGELYISGASVARGYVNHDKLTSDKFSSDPFKPDVIMYRTGDLARRLEDGNIEYIG RADNQVKIRGYRIEPQEIEVTLMNHPDISEAAILIWQDQNGEHELCAYYCSVQKLNTI DLRSYMASELPEYMIPAKWIWVDSIPLTPNGKVDRAALPEPDASISGNPYTAPRNLLE AKLSQLFEDVLKNGHIGIQDNFFDNGGHSLKATVLMSRIAKEFHVQVSLKDIFAHPTV EGLALIIREAEQNLYAAIEPAEKRDTYPVSSAQKRIYVLQQLDEGVAYNMPAVLELEG ALDVAKLSAVCKELISRHEPLRTSFVSGADDEPVQRIHTEVPFTLSKETTIEGFVRPF DLSQAPLFRAGLIEVSNEKHVLLVDMHHIISDGVSVQLLIREFTDLYANRQLKPLRIQ YKDYAVWQQKFKKGDSYQKQETYWQQQFSGDLPILELPTDKRRPAERQFIGGKVTFQL DKEITARIKRLAHKNRSTLYMTLLALYSAFLSRLSGQDDIVIGSPIAGRPHADLEAVL GMFVNTLALRTRPAGNKTFEEFLKEVRQTALEAYEHQDYPFEELVDKLGVQREMSRNP LFDTTLVLQNMEQQKLKMNDVQLQWNDLEHPISKFDISLYVTEHDSELFCQFEYSTAL FEKETIQRWASLFTTLVEHTAASPETELDNIPILTKEEERDFIESCHLFEETGYSMNQ TLHYALEQQAEKTPDQAAVIFEDGVMTYKELNEQANRIAWELIGRGVKPETTVAIIGK RSPEMLLGIYGILKAGGAYLPIDPDYPEERISFLLEDSGTNILLLQSAGLHVPEFTGE IVYLNQTNSGLAHRLSNPNVDVLPQSLAYVIYTSGSTGMPKGVEIEHRSAVNFLNSLQ SRYQLKHSDMIMHKTSYSFDASIWELFWWPYAGASVYLLPQGGEKEPEVIAKAIEEQK ITAMHFVPSMLHAFLEHIKYRSVPIKTNRLKRVFSGGEQLGTHLVSRFYELLPNVSIT NSYGPTEATVEAAFFDCPPHEKLERIPIGKPVHHVRLYLLNQNQRMLPVGCIGELYIA GAGVARGYLNRPALTEERFLEDPFYPGERMYKTGDVARWLPDGNVEFLGRTDDQVKIR GYRIEPGEIEAALRSIEGVREAAVTVRTDSGEPELCAYVEGLQRNEVRAQLERLLPGY MVPAYMIEMEQWPVTPSGKLDRNALPAPGGAADAETYTAPRNVTEMKLSQLWEDVLKN GPVGIHDNFFDRGGHSLKATALVSRITKEFDVQVPLKDVFAHPTVEGLATVIREGTDS PYEAIKPAEKQETYPVSSAQKRIYVLQQLEDGGTGYNMPAVLELEGKLNPERMDRAFQ ELIKRHESLRTSFEQDEGGDPVQRIHDEVPFTLQTTVLGARTEQEAAAAFIKPFDLSQ APLFRAQIVKVSDERHLLLVDMHHIISDGVSVNILIQEFGELYNNRKLPALRIQYKDY AVWQEGFKTGDAYKMQEAYWLKQLEGELPVLDLPADHARPPVRSFAGDKVSFTLEPEV ASGLHKLARENGSTLYMVLLAAYTAFLSRLSGQEDIIVGSPIAGRPHKDLEPILGMFV NTLALRTRPEGGKPFVQYLQEVRETALEAFEHQNYPFEELVDKLELTRDMSRNPVFDA MLVVQNNDYEPLHLHDLQMKPAQVSHLVSKFDLTLQASEGDGNIHFLFEYSTALFEKT TIERWASHLTNVLSIIGKNPKVTLNHIDILTQEERHQLLNEFNTGQANQYGVQTISQL FEQQAARTPKASALVSGDKTLTYQELDEWSNGIARALRSRGVKPDTPVGIMMHRSFSM IASILGVWKAGGCYVPIDPEYPKERKRYILSDSGTKLLMTINEADLGVLADFEGEILT IESVEEDDKSPLPQMSSAHHLAYIIYTSGTTGRPKGVMVEHKGIANTLQWRRNAYAFN ETDTILQLFSFSFDGFITSMFTPLLSGAKAVLLHEEEAKDILAIKHQLSRQRITHMII VPVLYRALLDVVQPEDVKTLRVVTLAGEAADRELIARSLAICPHTELANEYGPTENSV ATTVMRHMEKQAYVSIGQPIDGTQVLILNSNHQLQPIGVAGELCIAGTGLARGYVNLP ELTERAFTQNPFKPEARMYRTGDAARWMADGTLEYLGRIDDQVKIRGYRVETKEIESV IRCIKGVKDAAVVAHVTASGQTELSAYVVTKPGLSTNAVRSELQNKLPVFMHPAFIEK LDSLPLSPNGKLDRGALPKPVYNHEGERPFLPPSSKMEQILADIWKEVLGAEKIGTAD SFFELGGDSIKALQVSARLHRIGKQMAVKDLFSHPTIQELAAYIRDSDTSSSQAAVEG DVQWSPVQKWFLSQDIKEKHHFNQSVMLHRSTSVQEDALRKTLKAITCHHDALRMVFT QNEQGKWDQYNRPLSHSDDALYGLQMIDLSAPDGTDGNRPYEPLIKRHVLDIQQKMDL KNGPLLQAGLFHTIDGDFLFLSAHHLVVDGISWRVLLEDLALGYRQAAGGEDIKLPPK TSSFKAYAKKLSDYAESQQLMKQLKYWREAEEYQTEALPFDQIDGTRAHEGQRSTISF TLNDKETAALLKDANSAYNTDTQDMLLASVILALRHWTNQSAFKLSLEGHGREDVLKG IDVSRTIGWFTAIYPLLIKLNADLPDSEESMVHVLKTTKDTLRRVPDKGFGYGVIKYL TPPGKKDINFTGAPEISFNYLGQFESGRTAEVPEEDAFSFSPLGAGGDISTTWNREQS LDISAIAAEGKLTVNMTYDNARFQRKTIEQLSETCRQFLLQLIEHCQNKSETEKTISD FDDQELTEDALQEIADMLSFH*" gene complement(1964045..1974856) /gene="ppsD" /locus_tag="BSU_18310" /old_locus_tag="BSU18310" promotor_-35 1967065..1967068 /Source="Nicolas_upshift_promotors" /id="U1480" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.696303696303696" /psig="0.87012987012987" /xcortree=1814 /SigmaFactorBS="cgtaacagcctccggctttccacacaccaagtatggatgCTA TcatactgaacgaacgaTGCATCATGATGCCTACTGGtgtgtccggcttaacacctcg g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 1967085..1967104 /Source="Nicolas_upshift_promotors" /id="U1480" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.696303696303696" /psig="0.87012987012987" /xcortree=1814 /SigmaFactorBS="cgtaacagcctccggctttccacacaccaagtatggatgCTA TcatactgaacgaacgaTGCATCATGATGCCTACTGGtgtgtccggcttaacacctcg g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 1967086 /Source="Nicolas_upshifts" /id="U1480" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.696303696303696" /psig="0.87012987012987" /xcortree=1814 /SigmaFactorBS="cgtaacagcctccggctttccacacaccaagtatggatgCTA TcatactgaacgaacgaTGCATCATGATGCCTACTGGtgtgtccggcttaacacctcg g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" CDS complement(1974881..1982548) /gene="ppsC" /locus_tag="BSU_18320" /old_locus_tag="BSU18320" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:9889147, 10471562, 16707694, 26284661, 28477175" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9889147, 10471562, 16707694, 26284661, 28477175; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="non-ribosomal plipastatin synthetase C involved in synthesis of plipastatin" /protein_id="NP_389714.1" /db_xref="EnsemblGenomes-Gn:BSU18320" /db_xref="EnsemblGenomes-Tr:CAB13715" /db_xref="GOA:P39847" /db_xref="InterPro:IPR000873" /db_xref="InterPro:IPR001242" /db_xref="InterPro:IPR006162" /db_xref="InterPro:IPR009081" /db_xref="InterPro:IPR010060" /db_xref="InterPro:IPR010071" /db_xref="InterPro:IPR020806" /db_xref="InterPro:IPR020845" /db_xref="InterPro:IPR025110" /db_xref="InterPro:IPR036736" /db_xref="SubtiList:BG10972" /db_xref="UniProtKB/Swiss-Prot:P39847" /translation="MPQQPEIQDIYPLSFMQEGMLFHSLYDEQSRAYFEQASFTIHGQ LDLERFQKSMDAVFDRYDIFRTAFIYKNVAKPRQVVLKQRHCPIHIEDISHLNERDKE HCTEAFKEQDKSKGFDLQTDVLMRISILKWAPDHYVCIWSHHHILMDGWCLGIVIKDF LHIYQALGKGQLPDLPPVQPYGTYIKWLMQQDREEAAEYWKKRLQHFEKSTPLPKRTD QIPNGTLQQITFAIPEKETAELQKIAAASGATLNTVFQALWGIMLQKVNRSSDAVFGS VISGRPSELKDVENMVGLFINTIPIRAQSDSLSFSDLVRRMQKDMNEAEAYSYFPLYD IQAQSALKQELIDHIIVFENTPTQQEIEELNQAGSFDFSVKDFEMEEVTNYSCSVKVI PGRTLYVRIHFQTSAYQPSMMSEIKDYLLHMVSDVISDPSLPVSKMTLLDEDKTRKIV SQNNRTVSVSPEAPTLHGLFERQAAVTPERLAIRFSGGSLTYAELDMYASRLAAHLAA RGVTNESIVGVLSERSPDMLIAVLAVLKAGGAYLPLDPAYPKERLSYMLKDSGASLLL TQPGCSAPNFSGETLEVDMTSLECEEVKRHVSASVSDGSLAYVIYTSGSTGQPKGVAV EHRQAVSFLTGMQHQFRLSEDDIVMVKTSFSFDASVWQLFWWALSGASAYLLPPGWEK DSALIVQAIHQENVTTAHFIPAMLNSFLDQAEIERLSDRTSLKRVFAGGEPLAPRTAA RFASVLPQVSLIHGYGPTEATVDAAFYVLDPERDRDRLRIPIGKPVPGARLYVLDPHL AVQPSGVAGELYIAGAGVARGYLNRPALTEERFLEDPFYLGERMYKTGDVARWLPDGN VEFLGRTDDQVKIRGYRIEPGEIEAALRSIEGVREAAVTVRTDSGEPELCAYVEGLQR NEVRAQLQRLLPGYMVPAYMIEMEQWPVTPSGKLDRNALPAPGGAADAETYTAPRNVT EMKLSQLWEDVLKNGPVGIHDNFFDRGGHSLKATALVSRIAKEFDVQVPLKDVFAHPT VEGLATVIREGTDSPYEAIKPAEKQETYPVSSAQKRIYVLQQLEDGGTGYNMPAVLEL EGKLNLERMDRAFKELIKRHESLRTAFEQDAGGDPVQRIHDEVPFTLQTTVLGARTEE EAAAAFIKPFDLSQAPLFRAQIVKVSDERHLLLVDMHHIISDGVSVNILIREFGELYN NRKLPALRIQYKDYAVWQEGFKTGDAYKTQGAYWLKQLEGELPVLDLPADHARPPMRS FAGDKVSFTLDQEVTSGLYKLARENGSTLYMVLLAAYTAFLSRLSGQEDIIVGSPIAG RPHKDLEPILGMFVNTLALRTRPEGGKPFVQYLQEVRETAMEAFEHQDYPFEELVDKL ELTRDMSRNPLFDVMFVLQNMDQESLELDELCLKPAANNGHQTSKFDLTLYAQEQPRG LLTFQMEFSTDLYKKKTIEKWLQYFNNMLLSIIKDNKAALGTINILNEDEAHYLIHEL NRTKIDYPRNETISRLFEMQAEQTPNAVAIVSDTQVFTYEDLNSWANQIASVLQIKGV GPDSVVALLTGRTPELIAGMLGILKAGGAYLPIDSNLPVERIAYMLSDSRAALLLQSE KTEKRLLGIECEQIIIEDIQKQGEAKNVESSAGPHSLAYIIYTSGSTGKPKGVMIEQR SVIRLVKNSNYITFTPEDRLLMTSSIGFDVGSFEIFGPLLNGAALHLSDQQTFLDSHQ LKRYIEHQGITTIWLTSSLFNHLTEQNEQTFSQLKHLIIGGEALSPSHVNRIRNVCPE VSIWNGYGPTENTTFSTCLHIQKTYELSIPIGRPVGNSTAFILNQWGVLQPVGAVGEL CVGGDGVARGYLGRPDLTKEKFVPHPFAPGDRLYRTGDLARWLSDGTIEYVGRIDDQV KVRGYRVELGEIETALRQIDGVKEAAVLARTAQTGSKELFGYISVKAGTNAEQVRSLL ARSLPNYMIPAYIIEMETLPLTSNGKLNRKALPEPDVASKQTYIPPRNELEEQLALIW QEVLGIQRIGIEDSFFELGGDSIKALQVSARLGRYGLSLQVSDLFRHPKIKDLSPFIR KSERIIEQGPIQGDVPWTPVQQWFFSQDIEERHHFNQSVMLFHSGRLSENALRPALKK LAEHHDALRMVYRNDDRRWIQINQGIHESQLYSLRISDLSQSESGWETKIKQEVADLQ QSINLQEGPLLHAALFKTLTGDYLFLAIHHLVVDGVSWRILLEDLSAGYQQAAAGQTI QLPPKTDSYQEYARRIQEYAQSSKLIREEAYWRSVEEQQAAELPYEIPHHVNIDFSKR DSLSFSLTEADTAVLLQNVNHAYGTDTQDILLTAASLAICEWTGGSKLRIAMEGHGRE HILPELDISRTVGWFTSMYPALISFENHRDELGTSVKTVKDTLGRIPNKGVGYGMLKY LTHPENKSITFSKTPEISFNYLGQFNDIERQDTFRPSSLGSGKDITHTWKREQIIEMS AMAADKKLHFNLSYPPARFHRNTMEQLINRIEHFLLDIMKHCAGQQKAEKTLSDFSSQ SLTAEDLDSISSLVEEL*" gene complement(1974881..1982548) /gene="ppsC" /locus_tag="BSU_18320" /old_locus_tag="BSU18320" CDS complement(1982565..1990247) /gene="ppsB" /locus_tag="BSU_18330" /old_locus_tag="BSU18330" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:9889147, 10471562, 16707694, 26284661, 28477175" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9889147, 10471562, 16707694, 26284661, 28477175; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="nonribosomal plipastatin synthetase B involved in synthesis of plipastatin" /protein_id="NP_389715.1" /db_xref="EnsemblGenomes-Gn:BSU18330" /db_xref="EnsemblGenomes-Tr:CAB13716" /db_xref="GOA:P39846" /db_xref="InterPro:IPR000873" /db_xref="InterPro:IPR001242" /db_xref="InterPro:IPR006162" /db_xref="InterPro:IPR009081" /db_xref="InterPro:IPR010060" /db_xref="InterPro:IPR010071" /db_xref="InterPro:IPR020806" /db_xref="InterPro:IPR020845" /db_xref="InterPro:IPR025110" /db_xref="InterPro:IPR036736" /db_xref="SubtiList:BG10971" /db_xref="UniProtKB/Swiss-Prot:P39846" /translation="MAQSAQIQDIYPLSHMQEGMLFHSLMDFSSKAYIEQTSFTITGN LCVDSFQKSLNLLVSRYDIFRTIFIKEVPDLTGPQQVVLSNRELTVYREDISRLADQE QQTLIDAFMTKDREKGFDLQKDPLMRLALFDRGDSQYTCVWTHHHIIMDGWCLGIILK EFFSMYDSLKNNSPVQLGSTVPYSRYIEWLGEQDQEETAAYWSEYLKEYGNTASIPRI KRRTADGNYKADQVSFSLAPDMVEKLTEAAQNWGVTLNTLFMSIWGVLLHRYNAADDA VFGSVISGRPSAIDGIESMVGLFINTVPVRIRSAEGITFSSLVKAVQEDILSSEQHGY YPLYEIQNHSPLKQGLIDHIFVFENYPVQLHQALSVESENDEGALKLSDISMSEQTNY DFNIVIVPGESFYIKFSYNADVYEREEMLRIQGHLKQALDCILTNPDVAVSDINIVPP EEQQVIQLFNETERPYVNKTIPQLFEEQAHKTPEAAALKMGNECWTYRQLQVRANQIA HALIEKGVGSGDIVAVMMGRSMEMPAALLGIWKAGGAYMPLDPHFPAERLSFLLKDSQ AAQLLIEEDLISLIPPSYEGNTITIEHTESYQTEAPNMPPGDLAYLIYTSGTTGRPKG VLVDHHGIANTLQWRREEYSMTEQDISLHLFSYVFDGCVTSLFTPLLSGACVLLTTDD EAKDVLALKRKIARYKVSHMIIVPSLYRVLLEVMTADDAKSLRIVTFAGEAVTPDLLE LNQIICPSAELANEYGPTENSVATTILRHLNKKERITIGHPIRNTKVFVLHGNQMQPI GAAGELCISGAGLARGYYKQQELTQKAFSDHPFLEGERLYRTGDAGRFLPDGTIEYIG RFDDQVKIRGYRIELREIETVLRQAPGVKEAAVLARDVSAEEKELVAYIVPEKGNSLP DLYQHLAGTLPSYMIPASIINISQMPLTSSGKLDRFALPEPENNTSVTYMAPRTLIEA DLAHIWEDVLNKQHIGIRDDFFQLGGQSLKAAALVSRIHKKLNVELPLSEVFSYPTVE SMAVKLMSLKEHAFTQIEPADQRDVYPLSFSQKRLYALHQLADDSTGYNMPAVLELRG NLNRQRLRSVLTELVNRHEALRTVFVLDRDEPVQIIYPEMAFDLKELEMESEQMLESA IETFIKPFYLSSGPLFRACVITMGNNRGFLLLDMHHIIADGVSMSTLVQEFTDLYCGK ELPALNLHYKDFAVWQQEKHPKELYKKQEAYWLGQLGGSLPTLELPLDKTRPRLPDFR GGTIEVNIDKDMADELHRLMAETGTTLYMILLAVYSILLSKLSGQEDIVVGSPAAGRP HADLERVIGMFVNTLAMRSKPEGHKTFSSYLHDIRHLALTAYEHQDYPFEELADKLDT NREVNRNPLFDAMLVLQSSEDFRFEVPGLSISSVTPKHDISKFDLTLHAEEHLSGIRC RFEYSTALFEEETITQWASYFIELVKGVTADTEMRISNMQLLPAAERRLLLEKMGQYA AYPRNENIVSLFEKQVAQYPEHIAVVCGHSQLTYRDLNEKAERAAAMLIKQGVRTGDI VGLMLDRSPDMIIGVLSILKAGGAYLPIDPEYPKERISFMLNDSGAKLLLTERGLNKP ADYTGHILYIDECENNSIPADVNIEEIVTDQPAYVIYTSGTTGQPKGVIVEHRNVISL LKHQNLPFEFNHEDVWTLFHSYCFDFSVWEMFGALLNGSTLVVVSKETARDPQAFRLL LKKERVTVLNQTPTAFYGLMLEDQNHTDHLNIRYVIFGGEALQPGLLQSWNEKYPHTD LINMYGITETTVHVTFKKLSAADIAKNKSNIGRPLSTLQAHVMDAHMNLQPTGVPGEL YIGGEGVARGYLNRDELTADRFVSNPYLPGDRLYRTGDLAKRLSNGELEYLGRIDEQV KVRGHRIELGEIQAALLQYPMIKEAAVITRADEQGQTAIYAYMVIKDQQAANISDIRT YLKNALPDFMLPARMIQIDSIPVTVNGKLDQKALPEPEKQAYTADDISPRNEIETVMA EIWEELLNVDELGVSANFFKLGGDSIKALQVCARLKQRGFETTVREMFEHQTLGELSA RVRKDVRAIDQGPVEGEITWTPIQQWFFSQSLESHHFNQSVMIYRAERFDEAALRKVL KSLVTHHDALRIVCRHEDGRQVQINRGIDLSDEELYALELFDVKDSLTEARNTIEEAA SRMQEHIRLETGPLLHAGLFRTENGDHLFLTIHHLVVDAVSWRILFEDFSTAYKQAVS GESIKLPQKTDSYLTYSQRIADYSISRQVQREAAYWDECENRHIQPIPKDNDAASNTF KDTEVIDFELSRHHTELLLTAAHKAYSTEMNDILLTALGLALQKWTGNNQFKISMEGH GRESYLEDIDISRTVGWFTSIYPVWLDMRDSDHKDKEERLGHLIKQTKDMLHRIPHKG AGYGVLKYISKRWGSQKNSPEISFNYLGQFDQDIQSNAFEVSDIKPGNEISPNWERPY ALDISGAVSSGCLNMHIIYNRFQFEEKTIQTFSRHFKQTLENIIEHCTGKENQEWSAS DFTDEDLTLDELSEIMGAVNKL*" gene complement(1982565..1990247) /gene="ppsB" /locus_tag="BSU_18330" /old_locus_tag="BSU18330" downshifts complement(1986236) /Source="Nicolas_upshifts" /id="D1002" /incds=1 /nref=2 /ntot=18 /MaxReadThrough="4.83331" /MaxDrop="4.93461" /score="20.5621533" /energy="-10.2" /TU="U1481,U1483" /idTUdmin="U1481" /TUdmin="-5742" /isTUend="FALSE" upshifts complement(1986280) /Source="Nicolas_upshifts" /id="U1481" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.962037962037962" /psig="0.000999000999001" /xcortree=13 /SigmaFactorBS="agctaagcgggcaagaggatattgttgtcggttCGCCtgctg ccggaagaccgcACGCTgatctggagcgcgtcatcggaatgttcgtcaatacattggc g" /listShort="ppsC" /GFF_Attribute="listLong" promotor_-10 complement(1986282..1986286) /Source="Nicolas_upshift_promotors" /id="U1481" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.962037962037962" /psig="0.000999000999001" /xcortree=13 /SigmaFactorBS="agctaagcgggcaagaggatattgttgtcggttCGCCtgctg ccggaagaccgcACGCTgatctggagcgcgtcatcggaatgttcgtcaatacattggc g" /listShort="ppsC" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 complement(1986304..1986307) /Source="Nicolas_upshift_promotors" /id="U1481" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.962037962037962" /psig="0.000999000999001" /xcortree=13 /SigmaFactorBS="agctaagcgggcaagaggatattgttgtcggttCGCCtgctg ccggaagaccgcACGCTgatctggagcgcgtcatcggaatgttcgtcaatacattggc g" /listShort="ppsC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 1986583..1986587 /Source="Nicolas_upshift_promotors" /id="U1482" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.547452547452547" /psig="0.993006993006993" /xcortree=1818 /SigmaFactorBS="ccagtaggcctcctgttttttgtatagctctttcgggtgctt cTCTTGctgccaaacagcaaaATCCTTATAATGCAGGTTTAaagctggcaactctttt c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 1986600 /Source="Nicolas_upshifts" /id="U1482" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.547452547452547" /psig="0.993006993006993" /xcortree=1818 /SigmaFactorBS="ccagtaggcctcctgttttttgtatagctctttcgggtgctt cTCTTGctgccaaacagcaaaATCCTTATAATGCAGGTTTAaagctggcaactctttt c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 1986603..1986622 /Source="Nicolas_upshift_promotors" /id="U1482" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.547452547452547" /psig="0.993006993006993" /xcortree=1818 /SigmaFactorBS="ccagtaggcctcctgttttttgtatagctctttcgggtgctt cTCTTGctgccaaacagcaaaATCCTTATAATGCAGGTTTAaagctggcaactctttt c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" CDS complement(1990272..1997957) /gene="ppsA" /locus_tag="BSU_18340" /old_locus_tag="BSU18340" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:9889147, 10471562, 14762003, 16707694, 26284661, 26268540" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9889147, 10471562, 14762003, 16707694, 26284661, 26268540; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="non-ribosomal plipastatin synthetase A involved in synthesis of plipastatin" /protein_id="NP_389716.2" /db_xref="EnsemblGenomes-Gn:BSU18340" /db_xref="EnsemblGenomes-Tr:CAB13717" /db_xref="GOA:P39845" /db_xref="InterPro:IPR000873" /db_xref="InterPro:IPR001242" /db_xref="InterPro:IPR006162" /db_xref="InterPro:IPR009081" /db_xref="InterPro:IPR010060" /db_xref="InterPro:IPR010071" /db_xref="InterPro:IPR020806" /db_xref="InterPro:IPR020845" /db_xref="InterPro:IPR025110" /db_xref="InterPro:IPR036736" /db_xref="SubtiList:BG10970" /db_xref="UniProtKB/Swiss-Prot:P39845" /translation="MSEHTYSLTHAQRRVWFTELLEPDTSICNLTACVKFKGNIELDT LEGALNHSISRNDAIRFQLLEGEELEPRLHLTEYKYYPLRIIDFSNVEMIEIEQWIQD QASIPFKLFNSPLFQFYLLRIDSHEVWLFAKFHHIIMDGISLNVMGNQIIDLYQKMKK KDPLPDQPEPSYLSYIEKESQYLQSPRFAKDRLFWTQTFEHPLEYHSLADQTSLQKQS TSASRDTIILSPDLEQTIRIFCEEHKINIISLFMASFYICISRITSKKDLAIGTYYGN RGSKAEKEMLGMFVSSLPIRITVDPDTDFLSFVRTIGREQLSVMRHQRFPYNLLVNEL RNEQKDLHNLIGISMQYQPLQWHNADDFDYETALYFSGYTANELSVQIQERIDNGTIQ LNFDYQNTLFSLEDIKRIQSHLLTILENALKHPHSFIRELDMTNTREKQKLLYEFNKT EAVSPKAFTLHGLFERQAAFTPERLAIRFSGGSLTYAELDMYASRLAAHLAARGVTNE SIVGVLSERSPDMLIAVLAVLKAGGAYLPLDPAYPKERLSYMLKDSGASLLLTQPGCS APNFSGETLEVDMTSLASEKAENHEFTPADGGSLAYVIYTSGSTGQPKGVAVEHRQAV SFLTGMQHQFPLSEDDIVMVKTSFSFDASVWQLFWWSLSGASAYLLPPGWEKDSALIV QAIHQENVTTAHFIPAMLNSFLDQAEIERLSDRTSLKRVFAGGEPLAPRTAARFASVL PQVSLIHGYGPTEATVDAAFYVLDPERDRDRLRIPIGKPVPGARLYVLDPHLAVQPSG VAGELYIAGAGVARGYLNRPALTEERFLEDPFYPGERMYKTGDVARWLPDGNVEFLGR TDDQVKIRGYRIEPGEIEAALRSIEGVREAAVTVRTDSGEPELCAYVEGLQRNEVRAQ LERLLPGYMVPAYMIEMEQWPVTPSGKLDRNALPAPGGAADAETYTAPRNVTEMKLSQ LWEDVLKNGPVGIHDNFFDRGGHSLKATALVSRIAKEFDVQVPLKDVFAHPTVEGLAT VIREGTDSPYEAIKPAEKQETYPVSSAQKRIYVLQQLEDGGTGYNMPAVLELEGKLNP ERMERAFKELIKRHESLRTSFEQDAGGDPVQRIHDEVPFTLQTTVLGERTEQEAAAAF IKPFDLSQAPLFRAQIVKISDERHLLLVDMHHIISDGVSVNILIREFGELYNNRNLPA LRIQYKDYAVWREGFKTGDAYKTQEAYWLKQLEGELPVLDLPADHARPPVRSFAGDKV SFTLDQEVASGLHKLARENGSTLYMVLLAAYTAFLSRLSGQEDIIVGSPIAGRPHKDL EPILGMFVNTLALRTRPEGGKPFVQYLQEVRETALEAFEHQDYPFEELVDKLELTRDM SRNPVFDAMFILQNVEKQDIDLREIKVRPANFAHHISLFDITLIATEISGSICCEMEF STEVFLKATIERWADHFIEFLHEALSTPETSLAQINILSDKEKQKIVFEFNKTQVEFA QKDIPFHRIFEAKAEENPEHIAVIDNETEISYRLLNERANRLARTLQNRKGPKPTVAV LAKRSIDAIVGVLAVMKAGGVYIPIDAHYPKARIEYILRDSGADILLLQRELKHLISN SPESEMSHIFLDDEGSFEESNCNLNLSPAPEEPVYIIYTSGTTGAPKGVIVTYQNFTH AALAWRQIYELDRKPVRLLQIASFSFDVFSGDLARTLTNGGTLIVCPDETRLEPAEIY KIIKSQRITVMESTPALIIPVMEYVYRNQFKLPDLDILILGSDMVKAQDFKTLTDRFG QSMRIINSYGVTEATIDSSFYETSMGGECTGDNVPIGSPLPNVHMYVLSQTDQIQPIG VAGELCIGGAGVAKGYHHKPDLTQMKFTENPFVSGERLYRTGDRACWLPNGTIRLLGR MDYQVKINGYRIETEEIESVLLQTGLVREAAVAVQHDKNGQAGLAAYIVPSDVNTNAL RAALTKELPAYMIPAYLIPLVNMPLTLNGKLDRNALPAPNNVLSRPYTAPVNDLQKTM AYIWEDVLSMSRVGIHDSFFELGGDSIKALQVAARLAAEGWSMTIRDLFRYSTIQELC GHITPLASQADQGPAEGEAELTPIQRRFFGQVHAFHYHYNQSVMLFSEKGFNANALHL ALRKITEHHDAIRMIFQRDQNGHVIQFNRGINHKDHELFGLYISDWTKASLERAHLDE KLAAEETVIQSKMNVEKGPLLQAGLFKTAEGDHLLIALHHLVIDGVSWRILLEDLAAA YQQALEKKEIQLPPKTDSYLSYADGLTQIAESKQLLSEKTYWQTILDAHTAFLPKDIE NVPDKLQMNSDAAAFVLSGDWTEKLLFETQQAYGTDANELLLTALGMALSEWTGHDQI VISTEGHGREGHVPNIDISRTVGWFTSIYPILLDMGIPEPFEDQLAYRIKTTKDMLRR VPNKGTGYGLLTHIGELRHKEPEVSFNYLGQFSEEKEVETFQLSYYQPRYEIAGERER EYELDINALITDGRLHVKAVYTQVFSKHSIECFMDRFHRHLIETIEHCSQKKAREKTL SDFSNKELTLSALSSIEDLVKDL*" gene complement(1990272..1997957) /gene="ppsA" /locus_tag="BSU_18340" /old_locus_tag="BSU18340" S_feature complement(1997958..1998066) /Source="Nicolas_S_feature" /locus_tag="new_1997958_1998066_c" /HighExp="T1.30H, T1.0H, T0.30H, S1, M0t90, T2.30H, LPhT, C90, LoTm, Lbstat" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.982" /TUlongSig="NA" /TUlongPSig="NA" /label="S679" promotor_-10 complement(1998051..1998070) /Source="Nicolas_upshift_promotors" /id="U1483" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.428571428571429" /psig="0.982017982017982" /xcortree=557 /SigmaFactorBS="attcaaaaaaaatgttataaaaatttaatgtttttTATTGTA CtttaaaaaatatcCGTTAATATAGTGCATATATggattatatagtcatataatttct t" /listShort="S679, ppsA, ppsB, ppsC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(1998066) /Source="Nicolas_upshifts" /id="U1483" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.428571428571429" /psig="0.982017982017982" /xcortree=557 /SigmaFactorBS="attcaaaaaaaatgttataaaaatttaatgtttttTATTGTA CtttaaaaaatatcCGTTAATATAGTGCATATATggattatatagtcatataatttct t" /listShort="S679, ppsA, ppsB, ppsC" /GFF_Attribute="listLong" promotor_-35 complement(1998084..1998091) /Source="Nicolas_upshift_promotors" /id="U1483" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.428571428571429" /psig="0.982017982017982" /xcortree=557 /SigmaFactorBS="attcaaaaaaaatgttataaaaatttaatgtttttTATTGTA CtttaaaaaatatcCGTTAATATAGTGCATATATggattatatagtcatataatttct t" /listShort="S679, ppsA, ppsB, ppsC" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(1998340..1999815) /gene="dacC" /locus_tag="BSU_18350" /old_locus_tag="BSU18350" /EC_number="3.4.16.4" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:9733705, 9864321, 11160090, 14731276, 17582436, 19758330" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9733705, 9864321, 11160090, 14731276, 17582436, 19758330; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="D-alanyl-D-alanine carboxypeptidase" /protein_id="NP_389717.1" /db_xref="EnsemblGenomes-Gn:BSU18350" /db_xref="EnsemblGenomes-Tr:CAB13718" /db_xref="GOA:P39844" /db_xref="InterPro:IPR000667" /db_xref="InterPro:IPR012338" /db_xref="PDB:1W5D" /db_xref="PDB:2J9P" /db_xref="SubtiList:BG10969" /db_xref="UniProtKB/Swiss-Prot:P39844" /translation="MKKSIKLYVAVLLLFVVASVPYMHQAALAAEKQDALSGQIDKIL ADHPALEGAMAGITVRSAETGAVLYEHSGDTRMRPASSLKLLTAAAALSVLGENYSFT TEVRTDGTLKGKKLNGNLYLKGKGDPTLLPSDFDKMAEILKHSGVKVIKGNLIGDDTW HDDMRLSPDMPWSDEYTYYGAPISALTASPNEDYDAGTVIVEVTPNQKEGEEPAVSVS PKTDYITIKNDAKTTAAGSEKDLTIEREHGTNTITIEGSVPVDANKTKEWISVWEPAG YALDLFKQSLKKQGITVKGDIKTGEAPSSSDVLLSHRSMPLSKLFVPFMKLSNNGHAE VLVKEMGKVKKGEGSWEKGLEVLNSTLPEFGVDSKSLVLRDGSGISHIDAVSSDQLSQ LLYDIQDQSWFSAYLNSLPVAGNPDRMVGGTLRNRMKGTPAQGKVRAKTGSLSTVSSL SGYAETKSGKKLVFSILLNGLIDEEDGKDIEDQIAVILANQ*" gene complement(1998340..1999815) /gene="dacC" /locus_tag="BSU_18350" /old_locus_tag="BSU18350" downshifts complement(1998352) /Source="Nicolas_upshifts" /id="D1003" /incds=0 /nref=126 /ntot=224 /MaxReadThrough="1.56173" /MaxDrop="5.81468" /score="20.5621533" /energy="-10.2" /TU="NA" /idTUdmin="U1484" /TUdmin="-16" /isTUend="TRUE" CDS complement(1999849..2000826) /gene="galM" /locus_tag="BSU_18360" /old_locus_tag="BSU18360" /EC_number="5.1.3.3" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:9733705, 12753898, 19758330" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9733705, 12753898, 19758330; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="aldose 1-epimerase" /protein_id="NP_389718.1" /db_xref="EnsemblGenomes-Gn:BSU18360" /db_xref="EnsemblGenomes-Tr:CAB13719" /db_xref="GOA:P39840" /db_xref="InterPro:IPR008183" /db_xref="InterPro:IPR011013" /db_xref="InterPro:IPR014718" /db_xref="PDB:3MWX" /db_xref="PDB:4BZE" /db_xref="PDB:4BZF" /db_xref="PDB:4BZG" /db_xref="PDB:4BZH" /db_xref="SubtiList:BG10253" /db_xref="UniProtKB/Swiss-Prot:P39840" /translation="MANFIEKITYLGTPAIKAGNEHLEMIVVPEWGSNVISLVDKTTN VQLLREPETAESFHDTPTLYGIPILFPPNRISDGTFSFRGRTYHFDINEKDKHNHLHG FLYHEKWNVVTTKQTDEGVIVETEIDLSELPHVQKQFPHHAVVRMTYTIKENTLFKHA TVMNKGKEAFPWGIGYHTTFIFPAESSLFSLTADQQWELDERLLPTGKLMDVPYKEAL HEGMDLRHKQLDDVFLSSYQKRGGENQAVIYHQHAHISIIYKADEQFKHWVVYNADGK QGYLCPEPYTWVTNAVNLDLPSSLTGLQVLEPGEETTAKSSITIELNHQ*" gene complement(1999849..2000826) /gene="galM" /locus_tag="BSU_18360" /old_locus_tag="BSU18360" promotor_-10 complement(2000855..2000873) /Source="Nicolas_upshift_promotors" /id="U1484" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.985014985014985" /psig="0.985014985014985" /xcortree=537 /SigmaFactorBS="gtgtttttttatttgataggggaaaatataaaatGGAGGAAA TatggtacagtaCATTGAATTCTTATACTAGcaatgaatcaaggagaggttgagtaaa c" /listShort="yoxA, dacC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2000867) /Source="Nicolas_upshifts" /id="U1484" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.985014985014985" /psig="0.985014985014985" /xcortree=537 /SigmaFactorBS="gtgtttttttatttgataggggaaaatataaaatGGAGGAAA TatggtacagtaCATTGAATTCTTATACTAGcaatgaatcaaggagaggttgagtaaa c" /listShort="yoxA, dacC" /GFF_Attribute="listLong" promotor_-35 complement(2000885..2000893) /Source="Nicolas_upshift_promotors" /id="U1484" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.985014985014985" /psig="0.985014985014985" /xcortree=537 /SigmaFactorBS="gtgtttttttatttgataggggaaaatataaaatGGAGGAAA TatggtacagtaCATTGAATTCTTATACTAGcaatgaatcaaggagaggttgagtaaa c" /listShort="yoxA, dacC" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2000960..2002351) /gene="yoeA" /locus_tag="BSU_18370" /old_locus_tag="BSU18370" /function="16.1: Circulate" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406, 28472044; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative Na+-driven efflux transporter" /protein_id="NP_389719.2" /db_xref="EnsemblGenomes-Gn:BSU18370" /db_xref="EnsemblGenomes-Tr:CAB13720" /db_xref="GOA:O34474" /db_xref="InterPro:IPR002528" /db_xref="SubtiList:BG13548" /db_xref="UniProtKB/Swiss-Prot:O34474" /translation="METSQEPLVTQKKSKPSVWRSMSLFLVPLLLSNVLQSVGQLVGM MAVGRWLGVDAVAAVSSFFPLFFLLISFTIGIGSGSSILIGQAYGAKNEERLKAVVGT TLTFTFLLGVVLAVIGSIFTLDILRLMGTPENVIHVSANYARILFYAMPFMFLYFAYT TFLRGTGDSKTPFYTLIVSTVINIALLPVLILGMFGFPKLGIYGSAYATVISTIATFL VLMVYLRKRKHPLQFDKTVRRYLKMDKELLVLLLRLGVPASINMILVSLSEIAVISFV NHYGSNATAAYGVVNQVASYVQMPAVSLGIAVSIFAAQSIGANEFDRLKQVIRVGIWL NYIIGGVLIILIYVFSHQILSLFLTEQETLYIAHRLLMITLWSYLLFGNAQIISATMR ASGTVLWPTVISIFAIWGVEVPVAFVLSHYTKLEILGVWVGYPAAFAVSLLLIYGYYQ FVWKKKQITRLIQ*" gene complement(2000960..2002351) /gene="yoeA" /locus_tag="BSU_18370" /old_locus_tag="BSU18370" downshifts complement(2000974) /Source="Nicolas_upshifts" /id="D1004" /incds=0 /nref=74 /ntot=213 /MaxReadThrough="2.12119" /MaxDrop="5.14152" /score="31.8413544" /energy="-12.3" /TU="NA" /idTUdmin="U1486" /TUdmin=2 /isTUend="TRUE" downshifts 2001120 /Source="Nicolas_upshifts" /id="D1005" /incds=1 /nref=1 /ntot=3 /MaxReadThrough="1.76262" /MaxDrop="3.63403" /score="24.8192541" /energy="-9.3" /TU="NA" /idTUdmin="U1485" /TUdmin="-1452" /isTUend="FALSE" promotor_-35 2002141..2002147 /Source="Nicolas_upshift_promotors" /id="U1485" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=200 /SigmaFactorBS="acttcctgaaccgatcccaatcgtaaatgAGATTAAaagaaa aaataacGGGAAAAAGGATGATACAGctgccactgcatcaacaccgagccatctgcct a" /listShort="S680" /listLong="iseA" /label="promotor_-35" promotor_-10 2002161..2002179 /Source="Nicolas_upshift_promotors" /id="U1485" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=200 /SigmaFactorBS="acttcctgaaccgatcccaatcgtaaatgAGATTAAaagaaa aaataacGGGAAAAAGGATGATACAGctgccactgcatcaacaccgagccatctgcct a" /listShort="S680" /listLong="iseA" /label="promotor_-10" S_feature 2002172..2002505 /Source="Nicolas_S_feature" /locus_tag="new_2002172_2002505" /HighExp="M9-stat, Etha, Gly, S8, Sw, S7, B60, S6, Salt, C30" /AntisenseName="yoeA" /AntisenseCor="9.0133358617756607E-2" /AntisenseRegPval="-0.9" /CDS_PredictionProba="NA" /TUshortSig="SigB" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S680" upshifts 2002172 /Source="Nicolas_upshifts" /id="U1485" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=200 /SigmaFactorBS="acttcctgaaccgatcccaatcgtaaatgAGATTAAaagaaa aaataacGGGAAAAAGGATGATACAGctgccactgcatcaacaccgagccatctgcct a" /listShort="S680" /listLong="iseA" S_feature complement(2002352..2002456) /Source="Nicolas_S_feature" /locus_tag="new_2002352_2002456_c" /HighExp="S8, LBGstat, Etha, Cold, S7, T-1.40H, S2, C90, nit, C30" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="Sig-" /TUshortPSig="0.456" /TUlongSig="NA" /TUlongPSig="NA" /label="S681" promotor_no_box complement(2002416..2002516) /Source="Nicolas_upshift_promotors" /id="U1486" /multdbtbs="-" /comp="M1" /sig="Sig-" /pcomp="0.455544455544456" /psig="0.455544455544456" /xcortree=562 /SigmaFactorBS="ttacttgctagtttattcttcataagctaaaaagatgtgtaa aattagaagaatcgggaagggtttcataagtgcagtgatgaataataacatgttacat a" /listShort="S681, yoeA" /GFF_Attribute="listLong" /label="promotor_no_box" upshifts complement(2002456) /Source="Nicolas_upshifts" /id="U1486" /multdbtbs="-" /comp="M1" /sig="Sig-" /pcomp="0.455544455544456" /psig="0.455544455544456" /xcortree=562 /SigmaFactorBS="ttacttgctagtttattcttcataagctaaaaagatgtgtaa aattagaagaatcgggaagggtttcataagtgcagtgatgaataataacatgttacat a" /listShort="S681, yoeA" /GFF_Attribute="listLong" promotor_-35 2002478..2002483 /Source="Nicolas_upshift_promotors" /id="U1487" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.994005994005994" /psig="0.994005994005994" /xcortree=1154 /SigmaFactorBS="tatgaaacccttcccgattcttctaattttaCACATCttttt agcttatgaaGAATAAACTAGCAAGTAATggcgtattttttgtgagtaaaagaataaa a" /listShort="iseA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2002499..2002517 /Source="Nicolas_upshift_promotors" /id="U1487" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.994005994005994" /psig="0.994005994005994" /xcortree=1154 /SigmaFactorBS="tatgaaacccttcccgattcttctaattttaCACATCttttt agcttatgaaGAATAAACTAGCAAGTAATggcgtattttttgtgagtaaaagaataaa a" /listShort="iseA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2002507 /Source="Nicolas_upshifts" /id="U1487" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.994005994005994" /psig="0.994005994005994" /xcortree=1154 /SigmaFactorBS="tatgaaacccttcccgattcttctaattttaCACATCttttt agcttatgaaGAATAAACTAGCAAGTAATggcgtattttttgtgagtaaaagaataaa a" /listShort="iseA" /GFF_Attribute="listLong" promotor_-35 2002565..2002572 /Source="Nicolas_upshift_promotors" /id="U1488" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.353646353646354" /psig="0.993006993006993" /xcortree=1549 /SigmaFactorBS="ttgtgagtaaaagaataaaaaataatttatgcaaaagTATTG TAAtctatccgtaatTATTGTAACATTTGTAACATaagagaaagagattttgaaggag a" /listShort="iseA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2002585..2002604 /Source="Nicolas_upshift_promotors" /id="U1488" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.353646353646354" /psig="0.993006993006993" /xcortree=1549 /SigmaFactorBS="ttgtgagtaaaagaataaaaaataatttatgcaaaagTATTG TAAtctatccgtaatTATTGTAACATTTGTAACATaagagaaagagattttgaaggag a" /listShort="iseA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2002588 /Source="Nicolas_upshifts" /id="U1488" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.353646353646354" /psig="0.993006993006993" /xcortree=1549 /SigmaFactorBS="ttgtgagtaaaagaataaaaaataatttatgcaaaagTATTG TAAtctatccgtaatTATTGTAACATTTGTAACATaagagaaagagattttgaaggag a" /listShort="iseA" /GFF_Attribute="listLong" CDS 2002637..2003182 /gene="iseA" /locus_tag="BSU_18380" /old_locus_tag="BSU18380" /function="16.3: Control" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:17483219, 17581128, 18761694, 22720735, 23091053" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 17483219, 17581128, 18761694, 22720735, 23091053; Product type r: regulator" /codon_start=1 /transl_table=11 /product="inhibitor of DL-endopeptidases involved in cell-separation" /protein_id="NP_389720.2" /db_xref="EnsemblGenomes-Gn:BSU18380" /db_xref="EnsemblGenomes-Tr:CAB13721" /db_xref="InterPro:IPR031841" /db_xref="PDB:2RSX" /db_xref="SubtiList:BG13549" /db_xref="UniProtKB/Swiss-Prot:O34841" /translation="MKKCLLFLTTIALILSLSTNAFAKNTSGDLSQKQALQLALSARE HFWNTMSGHNPKVKKAVCPSGTFEYQNLQYVYMCSDLGTKAKAVNYLTPIFTKTAIEK GFKDYHFTVSKGKLAVPIGDGDNLLNWKKSTAKLISKKGSTITYEFTVPTLDGSPSAK RKVTFVKENKKWKVNQFDAVI*" gene 2002637..2003182 /gene="iseA" /locus_tag="BSU_18380" /old_locus_tag="BSU18380" downshifts 2003166 /Source="Nicolas_upshifts" /id="D1006" /incds=0 /nref=164 /ntot=264 /MaxReadThrough="4.38689" /MaxDrop="8.27665" /score="24.8192541" /energy="-9.3" /TU="NA" /idTUdmin="U1487" /TUdmin=0 /isTUend="TRUE" tRNA complement(2003276..2003348) /gene="trnSL-Arg1" /locus_tag="BSU_tRNA_85" /product="tRNA-Arg" /inference="profile:tRNAscan:1.23" /note="Evidence 2a: Function from experimental evidences in other organisms; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene complement(2003276..2003348) /gene="trnSL-Arg1" /locus_tag="BSU_tRNA_85" downshifts complement(2003374) /Source="Nicolas_upshifts" /id="D1007" /incds=0 /nref=4 /ntot=118 /MaxReadThrough="1.99821" /MaxDrop="3.03097" /score="3.94141467" /energy="-15.1" /TU="NA" /idTUdmin="U1489" /TUdmin=0 /isTUend="TRUE" CDS complement(2003401..2003946) /gene="yoeC" /locus_tag="BSU_18390" /old_locus_tag="BSU18390" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative bacteriophage integrase" /protein_id="NP_389721.2" /db_xref="EnsemblGenomes-Gn:BSU18390" /db_xref="EnsemblGenomes-Tr:CAB13722" /db_xref="GOA:O35009" /db_xref="InterPro:IPR002104" /db_xref="InterPro:IPR011010" /db_xref="InterPro:IPR013762" /db_xref="SubtiList:BG13550" /db_xref="UniProtKB/Swiss-Prot:O35009" /translation="MHIVQPIRSLEKIQEVKQYLLNKNKRDYFLFIFGINSALRISDI LPLQVKDVQNKDHLWATESKTKKKRKILILESLKQEIYEYTKDMKENEYLFKSVRTRK PISRIQAYRILREAAAACGLEEIGTHTLRKTFGYHFYQRTKDIAELQRILNHSSPSIT MRYIGIDEDTTRAAYKVFGGL*" gene complement(2003401..2003946) /gene="yoeC" /locus_tag="BSU_18390" /old_locus_tag="BSU18390" promotor_-10 complement(2003986..2004005) /Source="Nicolas_upshift_promotors" /id="U1489" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.642357642357642" /psig="0.999000999001" /xcortree=2388 /SigmaFactorBS="actatgtatattatgttacataaacgccgccgcaCTTTGACA ttcaacgtttttcAGCTATAATAGTAACATAGAcctcaaaatgttacataacggtttt t" /listShort="yoeC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2004000) /Source="Nicolas_upshifts" /id="U1489" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.642357642357642" /psig="0.999000999001" /xcortree=2388 /SigmaFactorBS="actatgtatattatgttacataaacgccgccgcaCTTTGACA ttcaacgtttttcAGCTATAATAGTAACATAGAcctcaaaatgttacataacggtttt t" /listShort="yoeC" /GFF_Attribute="listLong" promotor_-35 complement(2004019..2004026) /Source="Nicolas_upshift_promotors" /id="U1489" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.642357642357642" /psig="0.999000999001" /xcortree=2388 /SigmaFactorBS="actatgtatattatgttacataaacgccgccgcaCTTTGACA ttcaacgtttttcAGCTATAATAGTAACATAGAcctcaaaatgttacataacggtttt t" /listShort="yoeC" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2004262..2004492) /gene="yoeD" /locus_tag="BSU_18400" /old_locus_tag="BSU18400" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 16880568; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative excisionase" /protein_id="NP_389722.1" /db_xref="EnsemblGenomes-Gn:BSU18400" /db_xref="EnsemblGenomes-Tr:CAB13723" /db_xref="GOA:O34555" /db_xref="InterPro:IPR010093" /db_xref="SubtiList:BG13551" /db_xref="UniProtKB/Swiss-Prot:O34555" /translation="MYLTIEETAEYTNLSEDYIKSLVLEGKIRAVHDGEQFLIYKEQF KTHLEQLENYKALVQEILNEPIPEDIDVKDED*" gene complement(2004262..2004492) /gene="yoeD" /locus_tag="BSU_18400" /old_locus_tag="BSU18400" downshifts complement(2004276) /Source="Nicolas_upshifts" /id="D1008" /incds=0 /nref=193 /ntot=248 /MaxReadThrough="0.81591" /MaxDrop="5.75977" /score="19.8797745" /energy="-8.6" /TU="NA" /idTUdmin="U1490" /TUdmin="-1" /isTUend="TRUE" promotor_-10 complement(2004518..2004537) /Source="Nicolas_upshift_promotors" /id="U1490" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.931068931068931" /psig=1 /xcortree=2156 /SigmaFactorBS="atagtgcataatgccgtttttctgtgcagaattgaTTATATT gatatgagccaTGTGCTATATTAGAATCAGCatacggattaagaagggactgctatat g" /listShort="yoeD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2004530) /Source="Nicolas_upshifts" /id="U1490" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.931068931068931" /psig=1 /xcortree=2156 /SigmaFactorBS="atagtgcataatgccgtttttctgtgcagaattgaTTATATT gatatgagccaTGTGCTATATTAGAATCAGCatacggattaagaagggactgctatat g" /listShort="yoeD" /GFF_Attribute="listLong" promotor_-35 complement(2004549..2004555) /Source="Nicolas_upshift_promotors" /id="U1490" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.931068931068931" /psig=1 /xcortree=2156 /SigmaFactorBS="atagtgcataatgccgtttttctgtgcagaattgaTTATATT gatatgagccaTGTGCTATATTAGAATCAGCatacggattaagaagggactgctatat g" /listShort="yoeD" /GFF_Attribute="listLong" /label="promotor_-35" misc_feature complement(2004584..2004603) /Source="Nicolas_upshift_promotors" /id="U1491" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.656343656343656" /psig="0.971028971028971" /xcortree=1438 /SigmaFactorBS="gtattgttacaatcttagcgtaaaaaaattacagcgttttca caagtgacaAATGGTATATTATATAGTGCataatgccgtttttctgtgcagaattgat t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(2004594) /Source="Nicolas_upshifts" /id="U1491" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.656343656343656" /psig="0.971028971028971" /xcortree=1438 /SigmaFactorBS="gtattgttacaatcttagcgtaaaaaaattacagcgttttca caagtgacaAATGGTATATTATATAGTGCataatgccgtttttctgtgcagaattgat t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 2004607..2004614 /Source="Nicolas_upshift_promotors" /id="U1492" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.763236763236763" /psig=1 /xcortree=470 /SigmaFactorBS="aaacggcattatgcactatataatataccatttgtCACTTGT GaaaacgctgtaatTTTTTTACGCTAAGATTGTAacaatacagcttcatataggaggg a" /listShort="ggt" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2004628..2004647 /Source="Nicolas_upshift_promotors" /id="U1492" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.763236763236763" /psig=1 /xcortree=470 /SigmaFactorBS="aaacggcattatgcactatataatataccatttgtCACTTGT GaaaacgctgtaatTTTTTTACGCTAAGATTGTAacaatacagcttcatataggaggg a" /listShort="ggt" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2004632 /Source="Nicolas_upshifts" /id="U1492" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.763236763236763" /psig=1 /xcortree=470 /SigmaFactorBS="aaacggcattatgcactatataatataccatttgtCACTTGT GaaaacgctgtaatTTTTTTACGCTAAGATTGTAacaatacagcttcatataggaggg a" /listShort="ggt" /GFF_Attribute="listLong" CDS 2004677..2006440 /gene="ggt" /locus_tag="BSU_18410" /old_locus_tag="BSU18410" /EC_number="2.3.2.2" /function="16.11: Scavenge (Catabolism)" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:8763966, 23335395, 24279353, 26370226, 28120195" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8763966, 23335395, 24279353, 26370226, 28120195; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="membrane bound gamma-glutamyltranspeptidase" /protein_id="NP_389723.1" /db_xref="EnsemblGenomes-Gn:BSU18410" /db_xref="EnsemblGenomes-Tr:CAB13724" /db_xref="GOA:P54422" /db_xref="InterPro:IPR000101" /db_xref="InterPro:IPR029055" /db_xref="PDB:2V36" /db_xref="PDB:3A75" /db_xref="PDB:3WHQ" /db_xref="PDB:3WHR" /db_xref="PDB:3WHS" /db_xref="SubtiList:BG11838" /db_xref="UniProtKB/Swiss-Prot:P54422" /translation="MKRTWNVCLTALLSVLLVAGSVPFHAEAKKPPKSYDEYKQVDVG KDGMVATAHPLASEIGADVLKKGGNAIDAAVAIQFALNVTEPMMSGIGGGGFMMVYDG KTKDTTIIDSRERAPAGATPDMFLDENGKAIPFSERVTKGTAVGVPGTLKGLEEALDK WGTRSMKQLITPSIKLAEKGFPIDSVLAEAISDYQEKLSRTAAKDVFLPNGEPLKEGD TLIQKDLAKTFKLIRSKGTDAFYKGKFAKTLSDTVQDFGGSMTEKDLENYDITIDEPI WGDYQGYQIATTPPPSSGGIFLLQMLKILDHFNLSQYDVRSWEKYQLLAETMHLSYAD RASYAGDPEFVNVPLKGLLHPDYIKERQQLINLDQVNKKPKAGDPWKYQEGSANYKQV EQPKDKVEGQTTHFTVADRWGNVVSYTTTIEQLFGTGIMVPDYGVILNNELTDFDAIP GGANEVQPNKRPLSSMTPTILFKDDKPVLTVGSPGGATIISSVLQTILYHIEYGMELK AAVEEPRIYTNSMSSYRYEDGVPKDVLSKLNGMGHKFGTSPVDIGNVQSISIDHENGT FKGVADSSRNGAAIGINLKRK*" gene 2004677..2006440 /gene="ggt" /locus_tag="BSU_18410" /old_locus_tag="BSU18410" downshifts 2006421 /Source="Nicolas_upshifts" /id="D1009" /incds=0 /nref=24 /ntot=49 /MaxReadThrough="1.41914" /MaxDrop="5.80171" /score="3.23845421" /energy="-10.4" /TU="NA" /idTUdmin="U1492" /TUdmin=0 /isTUend="TRUE" CDS complement(2006541..2007398) /gene="ftsR" /locus_tag="BSU_18420" /old_locus_tag="BSU18420" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:17526699" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 17526699; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator (LysR family)" /protein_id="NP_389724.1" /db_xref="EnsemblGenomes-Gn:BSU18420" /db_xref="EnsemblGenomes-Tr:CAB13725" /db_xref="GOA:O34685" /db_xref="InterPro:IPR000847" /db_xref="InterPro:IPR005119" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG13552" /db_xref="UniProtKB/Swiss-Prot:O34685" /translation="MESGDLKIFQAVAREGSITKAAQMLNYVQSNVTARVHNLEEDLN IRLFHRTNRGMKLTAAGENLLQYADQVLSLLDQAEKSTRMSRQPKGPLRIGSLETMAV THLPEHAASFLRRFPEVDLSVNTADTHHLIQQVLDHKVDGAFVYGPVEHAAVRQLHVS HDELVLISSREGTAEDMLQQPMLFFGAGCSHRDRVKRLLEEAGIHNQKIIEFGTLEAI IKGVSAGMGTALLPKSAVDGSEHRTNVWIHQLPPSYQDLEIVFIYRKDFFITSAFQTF LDEINEMKR*" gene complement(2006541..2007398) /gene="ftsR" /locus_tag="BSU_18420" /old_locus_tag="BSU18420" promotor_-10 complement(2007444..2007463) /Source="Nicolas_upshift_promotors" /id="U1493" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.632367632367632" /psig="0.998001998001998" /xcortree=3011 /SigmaFactorBS="ctgtctgcctcctcattaattgtattttcatatctttacaTA TTTTACatagcggttttctTCGAGTAAAATGAACAAATAtgatagccaatatcacttt t" /listShort="ftsR" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2007464) /Source="Nicolas_upshifts" /id="U1493" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.632367632367632" /psig="0.998001998001998" /xcortree=3011 /SigmaFactorBS="ctgtctgcctcctcattaattgtattttcatatctttacaTA TTTTACatagcggttttctTCGAGTAAAATGAACAAATAtgatagccaatatcacttt t" /listShort="ftsR" /GFF_Attribute="listLong" promotor_-35 complement(2007477..2007484) /Source="Nicolas_upshift_promotors" /id="U1493" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.632367632367632" /psig="0.998001998001998" /xcortree=3011 /SigmaFactorBS="ctgtctgcctcctcattaattgtattttcatatctttacaTA TTTTACatagcggttttctTCGAGTAAAATGAACAAATAtgatagccaatatcacttt t" /listShort="ftsR" /GFF_Attribute="listLong" /label="promotor_-35" CDS 2007526..2008515 /gene="yogA" /locus_tag="BSU_18430" /old_locus_tag="BSU18430" /EC_number="1.-.-.-" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 10960106, 23873705; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative oxidoreductase" /protein_id="NP_389725.1" /db_xref="EnsemblGenomes-Gn:BSU18430" /db_xref="EnsemblGenomes-Tr:CAB13726" /db_xref="GOA:O35017" /db_xref="InterPro:IPR011032" /db_xref="InterPro:IPR013149" /db_xref="InterPro:IPR013154" /db_xref="InterPro:IPR020843" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG13553" /db_xref="UniProtKB/Swiss-Prot:O35017" /translation="MKAVIHNGKAGLLGLSVQDVPSTKPGYGEVKVKLKSAGLNHRDL FLMKNKSEQDPHMILGSDGAGIIEEIGEGVKNVTVQTEVVIFPTLNWDLTENVPPVPE ILGGPSDGTLAEYVIIPSQNAIKKPAYLSWEEAGVLPLSALTAYRALFTKGQLKKGEH LLIPGIGSGVATYALFMAKAIGATVSVTSRSEEKRKKALKLGADYAFDSYSNWDEQLQ GKKIDVVLDSIGPALFSEYFRHVKPNGRIVSFGASSGDNLSFPVRSLFFPQVNVLGTS MGSGEEFQAMLAFIDKHKLRPVIDRIYPLEKACEAYKRMQEGRQFGNIGIVME*" gene 2007526..2008515 /gene="yogA" /locus_tag="BSU_18430" /old_locus_tag="BSU18430" S_feature complement(2007582..2008540) /Source="Nicolas_S_feature" /locus_tag="new_2007582_2008540_c" /HighExp="T-4.40H, T-5.40H, Glu, GM 45, Glucon, GM-0.1, Gly, GM-0.2, UNK1, GM 90" /AntisenseName="yogA" /AntisenseCor="-0.49303153269799599" /AntisenseRegPval="-17.2" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S682" CDS complement(2008572..2010053) /gene="gltB" /locus_tag="BSU_18440" /old_locus_tag="BSU18440" /EC_number="1.4.1.13" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:3011766, 10651638, 11029411, 27223617" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 3011766, 10651638, 11029411, 27223617; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="glutamate synthase (small subunit, NADP-dependent)" /protein_id="NP_389726.2" /db_xref="EnsemblGenomes-Gn:BSU18440" /db_xref="EnsemblGenomes-Tr:CAB13727" /db_xref="GOA:O34399" /db_xref="InterPro:IPR006005" /db_xref="InterPro:IPR009051" /db_xref="InterPro:IPR023753" /db_xref="InterPro:IPR028261" /db_xref="InterPro:IPR036188" /db_xref="SubtiList:BG12594" /db_xref="UniProtKB/Swiss-Prot:O34399" /translation="MGKPTGFMEIKREKPAERDPLTRLKDWKEYSAPFSEEASKRQGA RCMDCGTPFCQIGADINGFTSGCPIYNLIPEWNDLVYRGRWKEALERLLKTNNFPEFT GRVCPAPCEGSCTLAISDPAVSIKNIERTIIDKGFENGWIQPRIPKKRTGKKVAIVGS GPAGLASADQLNQAGHSVTVFERADRAGGLLTYGIPNMKLEKGIVERRIKLLTQEGID FVTNTEIGVDITADELKEQFDAVILCTGAQKQRDLLIEGRDSKGVHYAMDYLTLATKS YLDSNFKDKQFIDAKGKDVIVIGGGDTGADCVATALRQKAKSVHQFGKHPKLPPARTN DNMWPEQPHVFTLEYAYEEAEAKFGRDPREYSIQTTKMVADKNGKLKELHTIQMEKVK NEHGKYEFRELPGTEKVWPAQLVFIAIGFEGTEQPLLKQFGVNSVNNKISAAYGDYQT NIDGVFAAGDARRGQSLIVWAINEGREVAREVDRYLMGSSVLP*" gene complement(2008572..2010053) /gene="gltB" /locus_tag="BSU_18440" /old_locus_tag="BSU18440" downshifts complement(2008585) /Source="Nicolas_upshifts" /id="D1010" /incds=0 /nref=247 /ntot=279 /MaxReadThrough="3.292" /MaxDrop="7.52772" /score="10.4717228" /energy="-6.5" /TU="U1495" /idTUdmin="U1495" /TUdmin="-570" /isTUend="FALSE" CDS complement(2010070..2014632) /gene="gltA" /locus_tag="BSU_18450" /old_locus_tag="BSU18450" /EC_number="1.4.1.13" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:39113, 3011766, 6769440, 6774712, 7559359, 14570271, 17134717" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 39113, 3011766, 6769440, 6774712, 7559359, 14570271, 17134717; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="glutamate synthase (large subunit, NADP-dependent)" /protein_id="NP_389727.2" /db_xref="EnsemblGenomes-Gn:BSU18450" /db_xref="EnsemblGenomes-Tr:CAB13728" /db_xref="GOA:P39812" /db_xref="InterPro:IPR002489" /db_xref="InterPro:IPR002932" /db_xref="InterPro:IPR006982" /db_xref="InterPro:IPR013785" /db_xref="InterPro:IPR017932" /db_xref="InterPro:IPR029055" /db_xref="InterPro:IPR036485" /db_xref="SubtiList:BG10811" /db_xref="UniProtKB/Swiss-Prot:P39812" /translation="MTYNQMPKAQGLYRPEFEHDACGIGLYAHLKGKQTHDIVKQGLK MLCQLDHRGGQGSDPDTGDGAGLLVQIPDAFFRKECKNINLPEKERYGVGMVFFSQKE DERKKIEKQINALIEQEGQVVLGWRTVPVNVGKIGTVAQKSCPFVRQVFIGASSDLKD NLSFERKLYVIRKQAENWGVTEGLDFYFASLSSQTIVYKGLLTPEQVDAFYSDLQDEA FVSAFALVHSRFSTNTFPTWERAHPNRYLVHNGEINTLRGNINWMRAREQQFVSESFG EDLNKILPILNADGSDSSILDNAFEFFVMAGRKPAHTAMMLIPEPWTENTHMSKEKRA FYEYHSSLMEPWDGPTAISFTDGKQIGAILDRNGLRPARYYVTKDDYIIFSSEVGVIE VEQENVLYKNRLEPGKMLLIDLEEGRIISDEEVKTQIATEYPYQKWLEEELVQVNPDP ESREEEQFSDLLTRQKAFGYTYEDIQKYLIPVIKEGKDPLGSMGNDAPLAVLSDRAQS LFNYFKQLFAQVTNPPIDAIREQLVTSTMTWLGAEGDLLHPSERNVRRIKLYTPVLSN EQFYALKTIVHPDLKSQKIDVLFSEDLERGLKDMFTQAEKAISQGVSLLILSDKKMNE RLTPIPPLLAVSALHQHLIRKGLRTKVSIIVESGEAREVHHFAALIGYGADAINPYLA YATYKQEIDEGRLDISYEEAVSKYGKSITEGVVKVMSKMGISTVQSYRGAQIFEAVGI SRDVIDRYFSGTASQLGGIDLQTIAEEAQRRHREAYQDDYSKTLEPGSDFQWRNGGEH HAFNPKTIHTLQWACRRNDYNLFKQYTKAADEERIGFLRNLFAFDGNRKPLKLEEVES AESIVKRFKTGAMSFGSLSKEAHEALAIAMNRLGGKSNSGEGGEDPKRFVPDENGDDR RSAIKQIASGRFGVKSHYLVNADELQIKMAQGAKPGEGGQLPGNKVYPWVADVRGSTP GVGLISPPPHHDIYSIEDLAQLIHDLKNANRDARISVKLVSKAGVGTIAAGVAKATAD VIVISGYDGGTGASPKTSIKHTGLPWELGLAEAHQTLMLNGLRDRVVLETDGKLMTGR DVVMAALLGAEEFGFATAPLVVLGCVMMRACHLDTCPVGVATQNPELRKKFMGDPDHI VNYMLFIAEEVREYMAALGFKTFDEMIGRTDVLHASERAKEHWKASQLDLSTLLYQPE GVRTFQSPQNHKIDQSLDITTILPAVQEAIESGKEADISIEINNTNRVAGTITGSEIS KRYGEEGLPEDTIKLHFTGSAGQSFGAFVPKGMTLYLDGDSNDYVGKGLSGGKIIVKS SEGFNSASDDNVIIGNVAFYGATSGEAYINGRAGERFAVRNSGVNVVVEGIGDHGCEY MTGGSVVVLGDVGKNFAAGMSGGIAYVLTEDVKAFKRKCNLEMILFESLEDEKEIQQI KAMLERHTAYTNSQKAEDLLDQWEDSVKKFVKVIPKNYKQMLASIEEQKAAGLSDEEA IMFAFEANTKPKQNTAASGQKQAVVQ*" gene complement(2010070..2014632) /gene="gltA" /locus_tag="BSU_18450" /old_locus_tag="BSU18450" promotor_no_box 2013093..2013193 /Source="Nicolas_upshift_promotors" /id="U1494" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.974025974025974" /psig="0.001998001998002" /xcortree=23 /SigmaFactorBS="taaagtagttaaacagcgattgcgctcggtcagaaagtacag caagcggagcgtcattccccattgaaccaaggggatctttgccttctttaataacagg a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_no_box" upshifts 2013153 /Source="Nicolas_upshifts" /id="U1494" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.974025974025974" /psig="0.001998001998002" /xcortree=23 /SigmaFactorBS="taaagtagttaaacagcgattgcgctcggtcagaaagtacag caagcggagcgtcattccccattgaaccaaggggatctttgccttctttaataacagg a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" S_feature complement(2014633..2014704) /Source="Nicolas_S_feature" /locus_tag="new_2014633_2014704_c" /HighExp="SMM, T-5.40H, HiOs, MG 15, Glu, T-4.40H, MG 150, MG 60, UNK1, MG 25" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S683" promotor_-10 complement(2014684..2014703) /Source="Nicolas_upshift_promotors" /id="U1495" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.95104895104895" /psig=1 /xcortree=3025 /SigmaFactorBS="catctatctcattttgagattcttttgatctaaattataTAT TGTTTatatcgttttgaaaACCTACAATGATTATAGAGTtgttagattttatgaccgg t" /listShort="S683, gltA, gltB, S682" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 2014701..2014708 /Source="Nicolas_upshift_promotors" /id="U1496" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.727272727272727" /psig="0.966033966033966" /xcortree=2238 /SigmaFactorBS="taataccggtcataaaatctaacaactctataatcattgtaG GTTTTCAaaacgatataaacaATATATAATTTAGATCAAAAgaatctcaaaatgagat a" /listShort="gltC" /GFF_Attribute="listLong" /label="promotor_-35" upshifts complement(2014704) /Source="Nicolas_upshifts" /id="U1495" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.95104895104895" /psig=1 /xcortree=3025 /SigmaFactorBS="catctatctcattttgagattcttttgatctaaattataTAT TGTTTatatcgttttgaaaACCTACAATGATTATAGAGTtgttagattttatgaccgg t" /listShort="S683, gltA, gltB, S682" /GFF_Attribute="listLong" promotor_-35 complement(2014718..2014725) /Source="Nicolas_upshift_promotors" /id="U1495" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.95104895104895" /psig=1 /xcortree=3025 /SigmaFactorBS="catctatctcattttgagattcttttgatctaaattataTAT TGTTTatatcgttttgaaaACCTACAATGATTATAGAGTtgttagattttatgaccgg t" /listShort="S683, gltA, gltB, S682" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 2014720 /Source="Nicolas_upshifts" /id="U1496" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.727272727272727" /psig="0.966033966033966" /xcortree=2238 /SigmaFactorBS="taataccggtcataaaatctaacaactctataatcattgtaG GTTTTCAaaacgatataaacaATATATAATTTAGATCAAAAgaatctcaaaatgagat a" /listShort="gltC" /GFF_Attribute="listLong" promotor_-10 2014723..2014742 /Source="Nicolas_upshift_promotors" /id="U1496" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.727272727272727" /psig="0.966033966033966" /xcortree=2238 /SigmaFactorBS="taataccggtcataaaatctaacaactctataatcattgtaG GTTTTCAaaacgatataaacaATATATAATTTAGATCAAAAgaatctcaaaatgagat a" /listShort="gltC" /GFF_Attribute="listLong" /label="promotor_-10" CDS 2014779..2015681 /gene="gltC" /locus_tag="BSU_18460" /old_locus_tag="BSU18460" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:2548995, 15150225, 17134717, 28294562" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 2548995, 15150225, 17134717, 28294562; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator (LysR family) (GltC-glutamate)" /protein_id="NP_389728.2" /db_xref="EnsemblGenomes-Gn:BSU18460" /db_xref="EnsemblGenomes-Tr:CAB13729" /db_xref="GOA:P20668" /db_xref="InterPro:IPR000847" /db_xref="InterPro:IPR005119" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG10810" /db_xref="UniProtKB/Swiss-Prot:P20668" /translation="MELRQLRYFMEVAEREHVSEAADHLHVAQSAISRQIANLEEELN VTLFEREGRNIKLTPIGKEFLIHVKTAMKAIDYAKEQIDEYLDPHRGTVKIGFPTSLA SQLLPTVISAFKEEYPHVEFLLRQGSYKFLIEAVRNRDIDLALLGPVPTNFSDITGKI LFTEKIYALVPLNHPLAKQKTVHLIDLRNDQFVLFPEGFVLREMAIDTCKQAGFAPLV STEGEDLDAIKGLVSAGMGVTLLPESTFAETTPRFTVKIPIEFPQVKRTVGIIKPKNR ELAPSANDFYEFVIQFFSKLEQYQ*" gene 2014779..2015681 /gene="gltC" /locus_tag="BSU_18460" /old_locus_tag="BSU18460" downshifts 2015661 /Source="Nicolas_upshifts" /id="D1011" /incds=0 /nref=104 /ntot=241 /MaxReadThrough="2.84467" /MaxDrop="3.98111" /score="22.3639229" /energy="-13.6" /TU="NA" /idTUdmin="U1496" /TUdmin=0 /isTUend="TRUE" CDS complement(2015733..2016848) /gene="proJ" /locus_tag="BSU_18470" /old_locus_tag="BSU18470" /EC_number="2.7.2.11" /function="16.8: Protect" /function="16.14: Store" /experiment="publication(s) with functional evidences, PMID:11418582, 15804359, 21784929, 28752945" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11418582, 15804359, 21784929, 28752945; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="glutamate 5-kinase" /protein_id="NP_389729.1" /db_xref="EnsemblGenomes-Gn:BSU18470" /db_xref="EnsemblGenomes-Tr:CAB13740" /db_xref="GOA:O07509" /db_xref="InterPro:IPR001048" /db_xref="InterPro:IPR001057" /db_xref="InterPro:IPR002478" /db_xref="InterPro:IPR005715" /db_xref="InterPro:IPR011529" /db_xref="InterPro:IPR015947" /db_xref="InterPro:IPR019797" /db_xref="InterPro:IPR036393" /db_xref="InterPro:IPR036974" /db_xref="SubtiList:BG12658" /db_xref="UniProtKB/Swiss-Prot:O07509" /translation="MTPDTSMKRVVVKIGSSSLTSLHGEISIRKLEALVDQVVKLKDA GYEVILVSSGAVAAGYRKLGFIQRPEKLPEKQASASIGQGLLMEAYSKLFLAHGYVAS QILITRSDFSDEYRYNNVRNTMNVLLERGIIPIINENDTVTVNRLKFGDNDTLAAKVA GLIDADMLVILSDIDGLYDGNPRTNPEAKKIQRVSEITPDIEACAGDTGSIVGTGGMR SKLDAFKIVMASGIKGFLGQADAGDILYHAVHEQAEGTYFEAEGTLPLNQKEQWIAFN SGPEGEMILSDDCSRKITNGQSSLYLDGVQKIKGKFKSGSVVRLMDSKGTEIGLGIVN YSSVQLQEPEKKKELTNRALIDQEAFVCHVDFSLPVN*" gene complement(2015733..2016848) /gene="proJ" /locus_tag="BSU_18470" /old_locus_tag="BSU18470" CDS complement(2016845..2017738) /gene="proH" /locus_tag="BSU_18480" /old_locus_tag="BSU18480" /EC_number="1.5.1.2" /function="16.2: Construct biomass (Anabolism)" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:11418582, 21784929, 22139509, 25344233, 28752945" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11418582, 21784929, 22139509, 25344233, 28752945; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="pyrroline-5-carboxylate reductase" /protein_id="NP_389730.2" /db_xref="EnsemblGenomes-Gn:BSU18480" /db_xref="EnsemblGenomes-Tr:CAB13741" /db_xref="GOA:P0CI77" /db_xref="InterPro:IPR000304" /db_xref="InterPro:IPR008927" /db_xref="InterPro:IPR028939" /db_xref="InterPro:IPR029036" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG11049" /db_xref="UniProtKB/Swiss-Prot:P0CI77" /translation="MRTKKRTKEMLPIFDQKKVAFIGAGSMAEGMISGIVRANKIPKQ NICVTNRSNTERLTELELQYGIKGALPNQLCIEDMDVLILAMKPKDAENALSSLKSRI QPHQLILSVLAGITTSFIEQSLLNEQPVVRVMPNTSSMIGASATAIALGKYVSEDLKK LAEALLGCMGEVYTIQENQMDIFTGIAGSGPAYFYYLMEFIEKTGEEAGLDKQLSRSI GAQTLLGAAKMLMETGEHPEILRDNITSPNGTTAAGLQALKKSGGGEAISQAIKHAAK RSKEISEDIEKTAAPLSGVIK*" gene complement(2016845..2017738) /gene="proH" /locus_tag="BSU_18480" /old_locus_tag="BSU18480" promotor_-10 complement(2017743..2017762) /Source="Nicolas_upshift_promotors" /id="U1497" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.498501498501498" /psig="0.999000999001" /xcortree=3035 /SigmaFactorBS="gtcgaaaagaaacaatacaaatcaataatggccttcaaaCTT GACAtcatttcctcacgTGGTAACATTTTAAACGTGTgaaaatgcgaacaaaaaagcg a" /listShort="proH, proJ" /GFF_Attribute="listLong" /label="promotor_-10" downshifts 2017751 /Source="Nicolas_upshifts" /id="D1012" /incds=0 /nref=1 /ntot=6 /MaxReadThrough="1.17009" /MaxDrop="3.27004" /score="-0.988973561" /energy="-13.3" /TU="NA" /idTUdmin="U1496" /TUdmin=2090 /isTUend="FALSE" upshifts complement(2017761) /Source="Nicolas_upshifts" /id="U1497" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.498501498501498" /psig="0.999000999001" /xcortree=3035 /SigmaFactorBS="gtcgaaaagaaacaatacaaatcaataatggccttcaaaCTT GACAtcatttcctcacgTGGTAACATTTTAAACGTGTgaaaatgcgaacaaaaaagcg a" /listShort="proH, proJ" /GFF_Attribute="listLong" promotor_-35 complement(2017776..2017782) /Source="Nicolas_upshift_promotors" /id="U1497" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.498501498501498" /psig="0.999000999001" /xcortree=3035 /SigmaFactorBS="gtcgaaaagaaacaatacaaatcaataatggccttcaaaCTT GACAtcatttcctcacgTGGTAACATTTTAAACGTGTgaaaatgcgaacaaaaaagcg a" /listShort="proH, proJ" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(2017791..2017809) /Source="Nicolas_upshift_promotors" /id="U1498" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1173 /SigmaFactorBS="gcgcagcagtgtgaaccgggtgttttctgcttttcattaTAC ATAtttgtcgaaaagaaaCAATACAAATCAATAATGGccttcaaacttgacatcattt c" /listShort="proH, proJ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2017809) /Source="Nicolas_upshifts" /id="U1498" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1173 /SigmaFactorBS="gcgcagcagtgtgaaccgggtgttttctgcttttcattaTAC ATAtttgtcgaaaagaaaCAATACAAATCAATAATGGccttcaaacttgacatcattt c" /listShort="proH, proJ" /GFF_Attribute="listLong" promotor_-35 complement(2017825..2017830) /Source="Nicolas_upshift_promotors" /id="U1498" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1173 /SigmaFactorBS="gcgcagcagtgtgaaccgggtgttttctgcttttcattaTAC ATAtttgtcgaaaagaaaCAATACAAATCAATAATGGccttcaaacttgacatcattt c" /listShort="proH, proJ" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2017886..2018254) /gene="rtp" /locus_tag="BSU_18490" /old_locus_tag="BSU18490" /function="16.9: Replicate" /experiment="publication(s) with functional evidences, PMID:11313334, 15657033, 16822523, 17376071, 17521668, 24946150" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11313334, 15657033, 16822523, 17376071, 17521668, 24946150; Product type f : factor" /codon_start=1 /transl_table=11 /product="replication terminator protein" /protein_id="NP_389731.1" /db_xref="EnsemblGenomes-Gn:BSU18490" /db_xref="EnsemblGenomes-Tr:CAB13742" /db_xref="GOA:P0CI76" /db_xref="InterPro:IPR003432" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="PDB:1BM9" /db_xref="PDB:1F4K" /db_xref="PDB:1J0R" /db_xref="PDB:2DPD" /db_xref="PDB:2DPU" /db_xref="PDB:2DQR" /db_xref="PDB:2EFW" /db_xref="SubtiList:BG10738" /db_xref="UniProtKB/Swiss-Prot:P0CI76" /translation="MKEEKRSSTGFLVKQRAFLKLYMITMTEQERLYGLKLLEVLRSE FKEIGFKPNHTEVYRSLHELLDDGILKQIKVKKEGAKLQEVVLYQFKDYEAAKLYKKQ LKVELDRCKKLIEKALSDNF*" gene complement(2017886..2018254) /gene="rtp" /locus_tag="BSU_18490" /old_locus_tag="BSU18490" promotor_-10 complement(2018289..2018307) /Source="Nicolas_upshift_promotors" /id="U1499" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.994005994005994" /psig="0.994005994005994" /xcortree=3198 /SigmaFactorBS="aatcagtaaacatgaaataactggactatcagtctttaatat aaaGAAGGAAAAcaataaaagaaAATTGAATATTTAGTACATagtgttgtcagtgaca g" /listShort="rtp" /listLong="proH" /label="promotor_-10" upshifts complement(2018312) /Source="Nicolas_upshifts" /id="U1499" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.994005994005994" /psig="0.994005994005994" /xcortree=3198 /SigmaFactorBS="aatcagtaaacatgaaataactggactatcagtctttaatat aaaGAAGGAAAAcaataaaagaaAATTGAATATTTAGTACATagtgttgtcagtgaca g" /listShort="rtp" /listLong="proH" S_feature complement(2018314..2018433) /Source="Nicolas_S_feature" /locus_tag="new_2018314_2018433_c" /HighExp="dia15, Etha, dia5, Diami, H2O2, LBGtran, LoTm, LBGexp, G180, dia0" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="1, 0.996" /TUlongSig="NA" /TUlongPSig="NA" /label="S684" promotor_-35 complement(2018319..2018327) /Source="Nicolas_upshift_promotors" /id="U1499" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.994005994005994" /psig="0.994005994005994" /xcortree=3198 /SigmaFactorBS="aatcagtaaacatgaaataactggactatcagtctttaatat aaaGAAGGAAAAcaataaaagaaAATTGAATATTTAGTACATagtgttgtcagtgaca g" /listShort="rtp" /listLong="proH" /label="promotor_-35" promotor_-10 complement(2018425..2018444) /Source="Nicolas_upshift_promotors" /id="U1500" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.955044955044955" /psig=1 /xcortree=2054 /SigmaFactorBS="gagatatgtaaaccctggcaatcgtttAAATTGAAgatagca gtaaatgCAGGCTATAATAGAACTAAGaaaactatgtaccaaatgttcagtcgaaatt t" /listShort="S684, rtp" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2018433) /Source="Nicolas_upshifts" /id="U1500" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.955044955044955" /psig=1 /xcortree=2054 /SigmaFactorBS="gagatatgtaaaccctggcaatcgtttAAATTGAAgatagca gtaaatgCAGGCTATAATAGAACTAAGaaaactatgtaccaaatgttcagtcgaaatt t" /listShort="S684, rtp" /GFF_Attribute="listLong" S_feature complement(2018435..2018531) /Source="Nicolas_S_feature" /locus_tag="new_2018435_2018531_c" /HighExp="Etha, dia15, LBGtran, LoTm, dia5, H2O2, LBGexp, M0t45, G135, G180" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.996" /TUlongSig="NA" /TUlongPSig="NA" /label="S685" promotor_-35 complement(2018459..2018466) /Source="Nicolas_upshift_promotors" /id="U1500" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.955044955044955" /psig=1 /xcortree=2054 /SigmaFactorBS="gagatatgtaaaccctggcaatcgtttAAATTGAAgatagca gtaaatgCAGGCTATAATAGAACTAAGaaaactatgtaccaaatgttcagtcgaaatt t" /listShort="S684, rtp" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2018554..2019270) /gene="yoxD" /locus_tag="BSU_18500" /old_locus_tag="BSU18500" /EC_number="1.-.-.-" /function="16.11: Scavenge (Catabolism)" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15317791; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative oxido-reductase" /protein_id="NP_389732.1" /db_xref="EnsemblGenomes-Gn:BSU18500" /db_xref="EnsemblGenomes-Tr:CAB13743" /db_xref="GOA:P14802" /db_xref="InterPro:IPR002347" /db_xref="InterPro:IPR020904" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG11048" /db_xref="UniProtKB/Swiss-Prot:P14802" /translation="MQSLQHKTALITGGGRGIGRATALALAKEGVNIGLIGRTSANVE KVAEEVKALGVKAAFAAADVKDADQVNQAVAQVKEQLGDIDILINNAGISKFGGFLDL SADEWENIIQVNLMGVYHVTRAVLPEMIERKAGDIINISSTAGQRGAAVTSAYSASKF AVLGLTESLMQEVRKHNIRVSALTPSTVASDMSIELNLTDGNPEKVMQPEDLAEYMVA QLKLDPRIFIKTAGLWSTNP*" gene complement(2018554..2019270) /gene="yoxD" /locus_tag="BSU_18500" /old_locus_tag="BSU18500" downshifts complement(2018576) /Source="Nicolas_upshifts" /id="D1013" /incds=0 /nref=109 /ntot=217 /MaxReadThrough="4.9568" /MaxDrop="5.08605" /score="27.1231718" /energy="-7.5" /TU="U1501" /idTUdmin="U1500" /TUdmin="-594" /isTUend="FALSE" promotor_-10 complement(2019308..2019327) /Source="Nicolas_upshift_promotors" /id="U1501" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.772227772227772" /psig="0.996003996003996" /xcortree=2690 /SigmaFactorBS="ttaatcagaagaaatgatatttacacagttcGTTTgatttgc gtattggaTGTATTGTACTTATAATGTGatatcgtacatatgtaaacaaagaaagggt g" /listShort="yoxD, S685, S684, rtp, proH" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2019317) /Source="Nicolas_upshifts" /id="U1501" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.772227772227772" /psig="0.996003996003996" /xcortree=2690 /SigmaFactorBS="ttaatcagaagaaatgatatttacacagttcGTTTgatttgc gtattggaTGTATTGTACTTATAATGTGatatcgtacatatgtaaacaaagaaagggt g" /listShort="yoxD, S685, S684, rtp, proH" /GFF_Attribute="listLong" promotor_-35 complement(2019343..2019346) /Source="Nicolas_upshift_promotors" /id="U1501" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.772227772227772" /psig="0.996003996003996" /xcortree=2690 /SigmaFactorBS="ttaatcagaagaaatgatatttacacagttcGTTTgatttgc gtattggaTGTATTGTACTTATAATGTGatatcgtacatatgtaaacaaagaaagggt g" /listShort="yoxD, S685, S684, rtp, proH" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 2019371..2019377 /Source="Nicolas_upshift_promotors" /id="U1502" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=228 /SigmaFactorBS="gcaaatcaaacgaactgtgtaaatatcatttcttcTGATTAA aaaaacggatacaGGGTAATGACATAAGAAAAggagtgaacatatgattatagtttat a" /listShort="yoxC, yoxB, yoaA, S686, S687" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2019391..2019409 /Source="Nicolas_upshift_promotors" /id="U1502" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=228 /SigmaFactorBS="gcaaatcaaacgaactgtgtaaatatcatttcttcTGATTAA aaaaacggatacaGGGTAATGACATAAGAAAAggagtgaacatatgattatagtttat a" /listShort="yoxC, yoxB, yoaA, S686, S687" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2019396 /Source="Nicolas_upshifts" /id="U1502" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=228 /SigmaFactorBS="gcaaatcaaacgaactgtgtaaatatcatttcttcTGATTAA aaaaacggatacaGGGTAATGACATAAGAAAAggagtgaacatatgattatagtttat a" /listShort="yoxC, yoxB, yoaA, S686, S687" /GFF_Attribute="listLong" CDS 2019421..2019726 /gene="yoxC" /locus_tag="BSU_18510" /old_locus_tag="BSU18510" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 16513748, 17598888; Product type ph: phenotype" /codon_start=1 /transl_table=11 /product="transition-dependent and sulfur-related metabolism protein" /protein_id="NP_389733.1" /db_xref="EnsemblGenomes-Gn:BSU18510" /db_xref="EnsemblGenomes-Tr:CAB13744" /db_xref="InterPro:IPR009293" /db_xref="SubtiList:BG11047" /db_xref="UniProtKB/Swiss-Prot:P28670" /translation="MIIVYISLAVLAVSIIFLGVTVIQNKKKIDPALKELSSVTQAMQ KQIEGLKTETELLTQKQKKIQQDVQIKKYTLQQTAAEVKEVPQAVKEVWQAGHFNSR* " gene 2019421..2019726 /gene="yoxC" /locus_tag="BSU_18510" /old_locus_tag="BSU18510" downshifts 2019710 /Source="Nicolas_upshifts" /id="D1014" /incds=0 /nref=6 /ntot=88 /MaxReadThrough="5.31272" /MaxDrop="3.8396" /score="-9.7711365" /energy="-17.8" /TU="U1502" /idTUdmin="U1503" /TUdmin="-1473" /isTUend="FALSE" CDS 2019797..2020567 /gene="yoxB" /locus_tag="BSU_18520" /old_locus_tag="BSU18520" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 11717291, 17598888, 19703276" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_389734.1" /db_xref="EnsemblGenomes-Gn:BSU18520" /db_xref="EnsemblGenomes-Tr:CAB13745" /db_xref="InterPro:IPR020530" /db_xref="InterPro:IPR036895" /db_xref="SubtiList:BG11046" /db_xref="UniProtKB/Swiss-Prot:P28671" /translation="MIINRSCLKEFAEKVHFLPSSLTKSDLLTDPFRLHQENELGIYY SPHNEFINRDASLVIAGITPGFSQMKTAYETAAESLLQGGTLEQMAVDTKIAAGFSGS MRHNLITMLDLCGLPQAFGIQSAAKLFGELRHMLHTTSVIKYPVFIQQKNYTGYKPAI THSPILSTYAFGHFPAELNHVTGPALLIPLGKAAETVCETLIRQHSLQNLICLNGFPH PSGANGHRLKQFSKNKEQLERQIRSFAALVDFAIEKRK*" gene 2019797..2020567 /gene="yoxB" /locus_tag="BSU_18520" /old_locus_tag="BSU18520" promotor_-35 2020549..2020556 /Source="Nicolas_upshift_promotors" /id="U1503" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.889110889110889" /psig="0.996003996003996" /xcortree=560 /SigmaFactorBS="gaaagacaaattcgttcctttgctgcattggttgatttcgcT ATAGAAAagaggaaataaaagGGATATGATAAACAAAAACAcaaacgtggggagtggt t" /listShort="yoaA" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 2020568 /Source="Nicolas_upshifts" /id="U1503" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.889110889110889" /psig="0.996003996003996" /xcortree=560 /SigmaFactorBS="gaaagacaaattcgttcctttgctgcattggttgatttcgcT ATAGAAAagaggaaataaaagGGATATGATAAACAAAAACAcaaacgtggggagtggt t" /listShort="yoaA" /GFF_Attribute="listLong" promotor_-10 2020571..2020590 /Source="Nicolas_upshift_promotors" /id="U1503" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.889110889110889" /psig="0.996003996003996" /xcortree=560 /SigmaFactorBS="gaaagacaaattcgttcctttgctgcattggttgatttcgcT ATAGAAAagaggaaataaaagGGATATGATAAACAAAAACAcaaacgtggggagtggt t" /listShort="yoaA" /GFF_Attribute="listLong" /label="promotor_-10" CDS 2020611..2021144 /gene="yoaA" /locus_tag="BSU_18530" /old_locus_tag="BSU18530" /EC_number="2.3.1.-" /function="16.8: Protect" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 10482513, 11717291, 17598888; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative N-acetyltransferase" /protein_id="NP_389735.2" /db_xref="EnsemblGenomes-Gn:BSU18530" /db_xref="EnsemblGenomes-Tr:CAB13746" /db_xref="GOA:O34569" /db_xref="InterPro:IPR000182" /db_xref="InterPro:IPR016181" /db_xref="SubtiList:BG13472" /db_xref="UniProtKB/Swiss-Prot:O34569" /translation="MFPILETDRLILRQITDQDAEAIFACFSNDEVTRYYGLENMESI EQAISMIQTFAALYQEKRGIRWGIERRDTKELIGTIGFHALAQKHRRAEIGYEIIPEH WRNGFASEVISKVVSYGFSALGLSRIGAVVFTDNEASNRLLLKMGFQKEGVLRQYMYQ NGTPYDTNVYSIVKPRE*" gene 2020611..2021144 /gene="yoaA" /locus_tag="BSU_18530" /old_locus_tag="BSU18530" S_feature 2021145..2021230 /Source="Nicolas_S_feature" /locus_tag="new_2021145_2021230" /HighExp="Salt, Sw, B60, LoTm, B36, M9-stat, BC, Lbstat, HiTm, Etha" /AntisenseName="yoaB" /AntisenseCor="-0.17521117067018899" /AntisenseRegPval="-2.4" /CDS_PredictionProba="NA" /TUshortSig="SigB" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S686" downshifts 2021187 /Source="Nicolas_upshifts" /id="D1015" /incds=0 /nref=6 /ntot=100 /MaxReadThrough="4.32682" /MaxDrop="3.67936" /score="-9.7711365" /energy="-17.8" /TU="U1502" /idTUdmin="U1503" /TUdmin=4 /isTUend="TRUE" CDS complement(2021223..2022467) /gene="yoaB" /locus_tag="BSU_18540" /old_locus_tag="BSU18540" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2b: Function from indirect experimental evidences (e.g. phenotypes); PubMedId: 12193636, 15849754, 16513748, 16850406, 28546427; Product type t : transporter" /codon_start=1 /transl_table=11 /product="negatively charged metabolite transporter" /protein_id="NP_389736.1" /db_xref="EnsemblGenomes-Gn:BSU18540" /db_xref="EnsemblGenomes-Tr:CAB13747" /db_xref="GOA:O34864" /db_xref="InterPro:IPR004748" /db_xref="InterPro:IPR011701" /db_xref="InterPro:IPR020846" /db_xref="InterPro:IPR036259" /db_xref="SubtiList:BG13473" /db_xref="UniProtKB/Swiss-Prot:O34864" /translation="MLDKIGIPKRLAWGFLGVVLFMMGDGLEQGWLSPFLIENGLTVQ QSASIFSIYGIALAIASWFSGVCLEAFGAKRTMFMGLLFYVIGTAAFIVFGFEQLNLP VMYVTYFVKGLGYPLFAYSFLTWVIYRTPQSKLSTAVGWFWIAYCLGMFVFGAWYSSY AIKAFGYLNTLWSSIFWVCLGAFFALFINKDRFEKKKRKRSETAEELLKGVTILFTNP RVLTGGIIRIINSIGTYGFPVFLPMHMAQHGISTNVWLQIWGTIFLGNIVFNLIFGIV GDKFGWKNTVIWFGGVGCGIFTVLLYYAPVFSGGSLAVVSVIGFIWGGLLAGYVPIGA IVPTVAGKDKGAAMSVLNLAAGLSAFVGPALAWLFIGLVGAQGVVWIFAALYLASAVL TKCIHIPEEKAVKEETSPQYAS*" gene complement(2021223..2022467) /gene="yoaB" /locus_tag="BSU_18540" /old_locus_tag="BSU18540" S_feature 2021232..2021971 /Source="Nicolas_S_feature" /locus_tag="new_2021232_2021971" /HighExp="LoTm, Salt, Sw, S6, Etha, M9-stat, LPhT, B60, T2.0H, T2.30H" /AntisenseName="yoaB" /AntisenseCor="-0.18536963552729299" /AntisenseRegPval="-2.6" /CDS_PredictionProba="NA" /TUshortSig="SigB" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S687" downshifts complement(2021237) /Source="Nicolas_upshifts" /id="D1016" /incds=0 /nref=32 /ntot=113 /MaxReadThrough="2.59019" /MaxDrop="4.97477" /score="29.0246554" /energy="-12.5" /TU="NA" /idTUdmin="U1504" /TUdmin=0 /isTUend="TRUE" S_feature complement(2022468..2022560) /Source="Nicolas_S_feature" /locus_tag="new_2022468_2022560_c" /HighExp="MG 10, MG 5, BMM, MG t5, MG 15, GM 25, HiTm, UNK1, GM 15, Gly" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S688" CDS complement(2022561..2024024) /gene="yoaC" /locus_tag="BSU_18550" /old_locus_tag="BSU18550" /EC_number="2.7.1.-" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2b: Function from indirect experimental evidences (e.g. phenotypes); PubMedId: 10094622, 12193636, 16850406, 18039762, 21749987, 27795321, 28546427; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="hydroxylated metabolite kinase" /protein_id="NP_389737.1" /db_xref="EnsemblGenomes-Gn:BSU18550" /db_xref="EnsemblGenomes-Tr:CAB13748" /db_xref="GOA:O34861" /db_xref="InterPro:IPR000577" /db_xref="InterPro:IPR018484" /db_xref="InterPro:IPR018485" /db_xref="SubtiList:BG13474" /db_xref="UniProtKB/Swiss-Prot:O34861" /translation="MKKQKGYLVFDIGTGNARVAVVSVTGSVLTVEREDIEYSTETLY PDSRYFSPQVLWKQVMNLAKRALSRSCDIDIIGLTSTSQRQGIVLIDQNGNPFLGLPN IDNRGREWEAGIPDWEEIYSSTGRLPTALFSALKLYGLKQRQPSLWEKTASFTSISDW VTYQLSGILTYEPSQATETLLFDVKQNTWSEEMCDIFGFSPSILPPLVRAGTAIGTIA NEYASELGLSINAKVIAGGGDTQLAVKSTGAGLEDIVIVSGTTTPITKITEDHGDTKH KAWLNCHTDQGHWLVETNPGITGLNYQKLKQIFYPNETYEVMEEEISALAKEDHACVA ALGSYLSAEKNALTRGGFLFDAPLSAHLKRAHFVRAALEEIAFSIKWNFDILTEVTPF ERDYVWVCGGGFQSKALTQYIADLLQKKVYVQEGYHQASVVGAAVICNETFQLTEEMS ANVRVIEPKDCQIELALYEEWKQTQRFFSGSESKVLI*" gene complement(2022561..2024024) /gene="yoaC" /locus_tag="BSU_18550" /old_locus_tag="BSU18550" CDS complement(2024042..2025076) /gene="yoaD" /locus_tag="BSU_18560" /old_locus_tag="BSU18560" /EC_number="1.1.1.-" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 10094622, 11390694, 12193636, 17012385, 18039762, 21749987, 27795321; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative 2-hydroxyacid dehydrogenase" /protein_id="NP_389738.1" /db_xref="EnsemblGenomes-Gn:BSU18560" /db_xref="EnsemblGenomes-Tr:CAB13749" /db_xref="GOA:O34815" /db_xref="InterPro:IPR006139" /db_xref="InterPro:IPR006140" /db_xref="InterPro:IPR029753" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG13475" /db_xref="UniProtKB/Swiss-Prot:O34815" /translation="MKNTMKRMFCSMTVLVTAPYNEEGRKELENLFGSVAYQSWKEQG RAYREDELIQLLKATNATGLITELDQVTDSVFASVPELSFVGVCRGMPSNVDVAAASK RGIPVFYTPGRNAQAVAEMFIGNVISFLRHTSASNQWLKDGEWDSDYLQAYVKFKGNE LTGKTVGMIGFGAVGQRIAKLLTAFDCKIKYYDPYIQDDHPLYEKASLKTVFSDSDIV SVHLPRTEETLGLIDRQYFDLMKESAIFVNTSRAVVVNREDLLFVLKEHKISGAILDV FYHEPPEESDYELISLPNVLATPHLAGATFEVEDHHVTILNKALKKWKGEKTLNIQTM YNKDALKTGG*" gene complement(2024042..2025076) /gene="yoaD" /locus_tag="BSU_18560" /old_locus_tag="BSU18560" S_feature complement(2025088..2025159) /Source="Nicolas_S_feature" /locus_tag="new_2025088_2025159_c" /HighExp="MG t5, MG 5, MG 10, BMM, GM 25, MG 15, Heat, GM 15, MG-0.2, M9-exp" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S689" downshifts complement(2025131) /Source="Nicolas_upshifts" /id="D1017" /incds=0 /nref=1 /ntot=24 /MaxReadThrough="7.78218" /MaxDrop="4.81701" /score="26.3160061" /energy="-11.4" /TU="U1504" /idTUdmin="U1507" /TUdmin=2727 /isTUend="FALSE" misc_RNA complement(2025160..2025251) /gene="mswF" /locus_tag="BSU_misc_RNA_31" /product="AdoMet riboswitch" /experiment="publication(s) with functional evidences, PMID:10094622, 12626738, 12910260, 17381305, 18039762" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10094622, 12626738, 12910260, 17381305, 18039762; Product type n: RNA" /function="16.3: Control" gene complement(2025160..2025251) /gene="mswF" /locus_tag="BSU_misc_RNA_31" promotor_-10 complement(2025279..2025298) /Source="Nicolas_upshift_promotors" /id="U1504" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.977022977022977" /psig=1 /xcortree=2890 /SigmaFactorBS="tccgatgataacgtcaattctgaaaaaaagaGATTGACAtca atctgagtcttCTTTATGATAAACGTATTCTtcattctgaaaattacatactcaatat t" /listShort="NA, S689, yoaD, yoaC, S688, yoaB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2025291) /Source="Nicolas_upshifts" /id="U1504" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.977022977022977" /psig=1 /xcortree=2890 /SigmaFactorBS="tccgatgataacgtcaattctgaaaaaaagaGATTGACAtca atctgagtcttCTTTATGATAAACGTATTCTtcattctgaaaattacatactcaatat t" /listShort="NA, S689, yoaD, yoaC, S688, yoaB" /GFF_Attribute="listLong" promotor_-35 complement(2025313..2025320) /Source="Nicolas_upshift_promotors" /id="U1504" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.977022977022977" /psig=1 /xcortree=2890 /SigmaFactorBS="tccgatgataacgtcaattctgaaaaaaagaGATTGACAtca atctgagtcttCTTTATGATAAACGTATTCTtcattctgaaaattacatactcaatat t" /listShort="NA, S689, yoaD, yoaC, S688, yoaB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 2025333..2025340 /Source="Nicolas_upshift_promotors" /id="U1505" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.977022977022977" /psig=1 /xcortree=3069 /SigmaFactorBS="gaagactcagattgatgtcaatctctttttttcagAATTGAC GttatcatcggaaaTGTTATAATTCTTACAAAATatctaactagagagaggaactggg c" /listShort="yoaE, yoaF" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2025354..2025373 /Source="Nicolas_upshift_promotors" /id="U1505" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.977022977022977" /psig=1 /xcortree=3069 /SigmaFactorBS="gaagactcagattgatgtcaatctctttttttcagAATTGAC GttatcatcggaaaTGTTATAATTCTTACAAAATatctaactagagagaggaactggg c" /listShort="yoaE, yoaF" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2025358 /Source="Nicolas_upshifts" /id="U1505" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.977022977022977" /psig=1 /xcortree=3069 /SigmaFactorBS="gaagactcagattgatgtcaatctctttttttcagAATTGAC GttatcatcggaaaTGTTATAATTCTTACAAAATatctaactagagagaggaactggg c" /listShort="yoaE, yoaF" /GFF_Attribute="listLong" CDS 2025400..2027442 /gene="yoaE" /locus_tag="BSU_18570" /old_locus_tag="BSU18570" /EC_number="1.-.-.-" /function="16.6: Maintain" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2b: Function from indirect experimental evidences (e.g. phenotypes); PubMedId: 2170332, 17114254; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="molybdopterin cofactor oxido-reductase" /protein_id="NP_389739.2" /db_xref="EnsemblGenomes-Gn:BSU18570" /db_xref="EnsemblGenomes-Tr:CAB13750" /db_xref="GOA:C0SP82" /db_xref="InterPro:IPR006655" /db_xref="InterPro:IPR006656" /db_xref="InterPro:IPR006657" /db_xref="InterPro:IPR006963" /db_xref="InterPro:IPR009010" /db_xref="SubtiList:BG13476" /db_xref="UniProtKB/Swiss-Prot:C0SP82" /translation="MRSFATQQNGIFKSVCSLDCPDQCGLLIHKKDGKIVKVQGDPDH PVTAGNICNKVRNMTERIYDEKRLTTPLKRTGAKGQAIFEPISWKEAIDTITSRWKQL IDEEGAESILPYSFYGNMGKLTAEGMDRRFFYRMGSSQLERTICSKAGSEGYKYTMGI SAGIDPEETVHTKLFIFWGINAVSTNMHQITIAQKARKKGAKIVVIDVHKNQTGRLAD WFIPIKPGTDSALALGIMHILFKENLHDEAFLSEYTVGYEELREHVKQYDPEKVSTIT GVSTEDIYRLAKMYGETSPSFIRIGNGPQHHDNGGMIVRTIACLPAITGQWLHTGGGA IKHNSGILEYNTNALQRPDLLKGRTPRSFNMNQLGRVLLETDPPIRSLFIYGTNPAVV APEANKVRQGLLREDLFTVVHDLFLTETAAYADIVLPATSAFENTDFYTSYWHHYIQL QQPVIERYGESKSNTEVFRLLAEAMGFTDQELKDSDEVLIRQALDHPDNPHLAEIDYD SLTKHSFMKAKREKPLFPGELPTPSGKIELYSEKMKQDGFPALPTYTPLVTDNEHPFM YVPGPNHNFLNSTFSNNEKHIKLEKTPKLFINTKDAEKHGIVDGAPVRIWNSRGECEL TAAVGEQVLPGVVVSQGLWADEQGKKQLVNALTPDRLSDMGGGATFFSGRVQIEKV*" gene 2025400..2027442 /gene="yoaE" /locus_tag="BSU_18570" /old_locus_tag="BSU18570" promotor_-35 2027450..2027459 /Source="Nicolas_upshift_promotors" /id="U1506" /multdbtbs="SigW" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1664 /SigmaFactorBS="aggccgtgtacagattgaaaaggtttgaaaaataaTGAAACC CGGagtatgccaagcCCGTATAACATAACATcgacataatggaggcatacacatggac g" /listShort="yoaF, S692, yozQ, S693" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2027472..2027487 /Source="Nicolas_upshift_promotors" /id="U1506" /multdbtbs="SigW" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1664 /SigmaFactorBS="aggccgtgtacagattgaaaaggtttgaaaaataaTGAAACC CGGagtatgccaagcCCGTATAACATAACATcgacataatggaggcatacacatggac g" /listShort="yoaF, S692, yozQ, S693" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2027475 /Source="Nicolas_upshifts" /id="U1506" /multdbtbs="SigW" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1664 /SigmaFactorBS="aggccgtgtacagattgaaaaggtttgaaaaataaTGAAACC CGGagtatgccaagcCCGTATAACATAACATcgacataatggaggcatacacatggac g" /listShort="yoaF, S692, yozQ, S693" /GFF_Attribute="listLong" CDS 2027509..2027802 /gene="yoaF" /locus_tag="BSU_18580" /old_locus_tag="BSU18580" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 23155385" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_389740.1" /db_xref="EnsemblGenomes-Gn:BSU18580" /db_xref="EnsemblGenomes-Tr:CAB13751" /db_xref="SubtiList:BG13477" /db_xref="UniProtKB/Swiss-Prot:O31829" /translation="MDVFLGIGIALAGYFIGEGLKQRNQTKGNEQNDIFLIKERDIYF YIGLFLGITTTEAKQLAGDMADLPYIEINGKKYVQKHMLKDWTFTLVEKHQGE*" gene 2027509..2027802 /gene="yoaF" /locus_tag="BSU_18580" /old_locus_tag="BSU18580" downshifts 2027782 /Source="Nicolas_upshifts" /id="D1018" /incds=0 /nref=97 /ntot=243 /MaxReadThrough="3.40762" /MaxDrop="4.1662" /score="-6.27063114" /energy="-3.9" /TU="U1506" /idTUdmin="U1505" /TUdmin=0 /isTUend="TRUE" S_feature complement(2027827..2028174) /Source="Nicolas_S_feature" /locus_tag="new_2027827_2028174_c" /HighExp="T0.30H, S0, T1.0H, aero, Etha, S8, SMMPr, T-0.40H, ferm, T-1.10H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigWXY" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S690" downshifts complement(2027858) /Source="Nicolas_upshifts" /id="D1019" /incds=0 /nref=43 /ntot=202 /MaxReadThrough="2.3171" /MaxDrop="4.25059" /score="-6.12586993" /energy="-17.4" /TU="NA" /idTUdmin="U1507" /TUdmin=0 /isTUend="TRUE" CDS complement(2028175..2028579) /gene="yoaG" /locus_tag="BSU_18590" /old_locus_tag="BSU18590" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 14563871, 15849754, 16850406, 20011599, 23155385; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative phage-related membrane protein" /protein_id="NP_389741.1" /db_xref="EnsemblGenomes-Gn:BSU18590" /db_xref="EnsemblGenomes-Tr:CAB13752" /db_xref="GOA:O31830" /db_xref="InterPro:IPR031374" /db_xref="SubtiList:BG13478" /db_xref="UniProtKB/Swiss-Prot:O31830" /translation="MKKIASYYLMTLGLSSLTFGLLLGFYSFVMYGDMIIALFTAAIA LLYGFVVYGLFAVPLQMKLQKKARTFNVMYLLIYSVVAFIAAFLFFVINEPASIAWTL QSYFYYMLSIAAAVIYWLWDSLILYKRTASGV*" gene complement(2028175..2028579) /gene="yoaG" /locus_tag="BSU_18590" /old_locus_tag="BSU18590" S_feature complement(2028580..2028675) /Source="Nicolas_S_feature" /locus_tag="new_2028580_2028675_c" /HighExp="T0.30H, T1.0H, T0.0H, T-0.40H, S0, T-1.10H, T-1.40H, SMMPr, Salt, Etha" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigWXY" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S691" promotor_-10 complement(2028665..2028680) /Source="Nicolas_upshift_promotors" /id="U1507" /multdbtbs="SigW" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1671 /SigmaFactorBS="ccagcgtattatctaataaaagaacgtcattttTGAAACCTT TtattagcgcattGCGTATAGCACGTTAGggaagacatctcgataaaagaaatacaaa g" /listShort="S691, yoaG, S690" /GFF_Attribute="listLong" /label="promotor_-10" CDS complement(2028665..2028784) /locus_tag="BSU_18595" /old_locus_tag="BSU18595" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_009513962.1" /translation="MHFFHSRFGQSGEAFSASVLSNKRTSFLKPFISALRIAR*" gene complement(2028665..2028784) /locus_tag="BSU_18595" /old_locus_tag="BSU18595" upshifts complement(2028675) /Source="Nicolas_upshifts" /id="U1507" /multdbtbs="SigW" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1671 /SigmaFactorBS="ccagcgtattatctaataaaagaacgtcattttTGAAACCTT TtattagcgcattGCGTATAGCACGTTAGggaagacatctcgataaaagaaatacaaa g" /listShort="S691, yoaG, S690" /GFF_Attribute="listLong" promotor_-35 complement(2028693..2028702) /Source="Nicolas_upshift_promotors" /id="U1507" /multdbtbs="SigW" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1671 /SigmaFactorBS="ccagcgtattatctaataaaagaacgtcattttTGAAACCTT TtattagcgcattGCGTATAGCACGTTAGggaagacatctcgataaaagaaatacaaa g" /listShort="S691, yoaG, S690" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 2028780..2028786 /Source="Nicolas_upshift_promotors" /id="U1508" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=915 /SigmaFactorBS="ctgattggccaaagcgcgaatgaaaaaagTGCATGAatacct gcccaacAGACAGAATAAGaagagttgatatttcaacacttttcgtaaaggggtgaaa c" /listShort="S692, yozQ, S693" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2028800..2028811 /Source="Nicolas_upshift_promotors" /id="U1508" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=915 /SigmaFactorBS="ctgattggccaaagcgcgaatgaaaaaagTGCATGAatacct gcccaacAGACAGAATAAGaagagttgatatttcaacacttttcgtaaaggggtgaaa c" /listShort="S692, yozQ, S693" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 2028811..2029019 /Source="Nicolas_S_feature" /locus_tag="new_2028811_2029019" /HighExp="S5, S8, S7, S6, S4, ferm, BT, nit, T5.0H, Pyr" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.99998799999999999" /TUshortSig="SigGF, SigWXY" /TUshortPSig="1, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S692" upshifts 2028811 /Source="Nicolas_upshifts" /id="U1508" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=915 /SigmaFactorBS="ctgattggccaaagcgcgaatgaaaaaagTGCATGAatacct gcccaacAGACAGAATAAGaagagttgatatttcaacacttttcgtaaaggggtgaaa c" /listShort="S692, yozQ, S693" /GFF_Attribute="listLong" CDS 2028854..2028976 /locus_tag="BSU_18596" /old_locus_tag="BSU18596" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="YP_009513963.1" /db_xref="EnsemblGenomes-Gn:BSU18596" /db_xref="EnsemblGenomes-Tr:CCQ48597" /db_xref="UniProtKB/TrEMBL:L8E9J0" /translation="MSKKGIQNSSIEQIRNDHETETAFKADDPKKHGSDPKRTK*" gene 2028854..2028976 /locus_tag="BSU_18596" /old_locus_tag="BSU18596" CDS 2029020..2029313 /gene="yozQ" /locus_tag="BSU_18600" /old_locus_tag="BSU18600" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 22882546" /codon_start=1 /transl_table=11 /product="putative sporulation protein" /protein_id="YP_054581.1" /db_xref="EnsemblGenomes-Gn:BSU18600" /db_xref="EnsemblGenomes-Tr:CAE01456" /db_xref="InterPro:IPR025100" /db_xref="SubtiList:BG14189" /db_xref="UniProtKB/Swiss-Prot:Q7WY68" /translation="MTQKNGADRPDDYKRFSSLDKEYDFQQSIRSNTETESVNTETQT HNKENKNDTTDVAGKYFEPSDYKGSTQLEKGLAETHEQVSDDYFEGTIDQNLD*" gene 2029020..2029313 /gene="yozQ" /locus_tag="BSU_18600" /old_locus_tag="BSU18600" S_feature 2029314..2029407 /Source="Nicolas_S_feature" /locus_tag="new_2029314_2029407" /HighExp="S5, S8, S6, S7, S4, BT, ferm, nit, T5.0H, G/S" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigGF, SigWXY" /TUshortPSig="1, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S693" downshifts 2029364 /Source="Nicolas_upshifts" /id="D1020" /incds=0 /nref=14 /ntot=74 /MaxReadThrough="3.32407" /MaxDrop="3.87581" /score="-6.27063114" /energy="-3.9" /TU="U1508" /idTUdmin="U1506" /TUdmin="-2" /isTUend="TRUE" CDS complement(2029429..2031114) /gene="yoaH" /locus_tag="BSU_18610" /old_locus_tag="BSU18610" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15033535, 27899502; Product type f: factor" /codon_start=1 /transl_table=11 /product="putative methyl-accepting chemotaxis protein" /protein_id="NP_389742.2" /db_xref="EnsemblGenomes-Gn:BSU18610" /db_xref="EnsemblGenomes-Tr:CAB13753" /db_xref="GOA:C0SP89" /db_xref="InterPro:IPR003660" /db_xref="InterPro:IPR004089" /db_xref="InterPro:IPR004090" /db_xref="InterPro:IPR007891" /db_xref="SubtiList:BG13479" /db_xref="UniProtKB/Swiss-Prot:C0SP89" /translation="MKVKTKLLGIISILVVSIIGIGGSSVFMISSTVKKNEELKDKME FQKEIKHIQYELTGLSNDERGFLITRDKEYDEGMKGKADDVLKSLDRVNDLIDEEKYQ SNIEDIKTSFTQYRALNQQVVTAYSSNPKKAETIHFGEERTIRKEGVAPAVNKLSDRL DQEVEDLKDEIQGNGKMSQSLIIIVTGISVILGIVLSIMLLKSIMVPLRSINKQLEEI AHGEADLTKKVIVKNKDEFGQLAQSFNSFTHSLTQIVKQISSSSEQVAASSEELSASA EESKSTSEHISRAMQMAADSNVKQSSMTEKSAESITELLDSISSVASNTGNIADLSSS MRDKAEIGSKSVNKMLDQMKFIDKSVDSAGNGLQTLVASTAEISDISSLITTISEQTN LLALNAAIEAARAGEQGKGFAVVAEEVRKLADETNKSANHIQSVVATIQNESIETVNN IKVVQENVSSGIVLSQETTGNFNEILNLVEQVTSQIQEVAAATQQLTSGVEVIQHTVH TLAAGTKETSANTEAVANSSQEQLHSMGEISYAAESLSQLAEELQTVINRFKY*" gene complement(2029429..2031114) /gene="yoaH" /locus_tag="BSU_18610" /old_locus_tag="BSU18610" downshifts complement(2029441) /Source="Nicolas_upshifts" /id="D1021" /incds=0 /nref=68 /ntot=193 /MaxReadThrough="2.22411" /MaxDrop="4.20676" /score="-6.12586993" /energy="-17.4" /TU="NA" /idTUdmin="U1509" /TUdmin="-21" /isTUend="TRUE" S_feature complement(2031115..2031202) /Source="Nicolas_S_feature" /locus_tag="new_2031115_2031202_c" /HighExp="Cold, C30, LBGstat, GM 90, GM 15, GM 45, GM 25, GM 60, GM 10, GM 120" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.115923" /TUshortSig="SigD" /TUshortPSig="0.998" /TUlongSig="NA" /TUlongPSig="NA" /label="S694" promotor_-10 complement(2031194..2031212) /Source="Nicolas_upshift_promotors" /id="U1509" /multdbtbs="SigD" /comp="M10" /sig="SigD" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=2825 /SigmaFactorBS="agaatttgcttattcatataagaatatcaCTATAAAActtga taacacgtGTCGATATTATGGACATGAgcgtaagcgaattggattcaaacgcgcttga a" /listShort="S694, yoaH" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2031202) /Source="Nicolas_upshifts" /id="U1509" /multdbtbs="SigD" /comp="M10" /sig="SigD" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=2825 /SigmaFactorBS="agaatttgcttattcatataagaatatcaCTATAAAActtga taacacgtGTCGATATTATGGACATGAgcgtaagcgaattggattcaaacgcgcttga a" /listShort="S694, yoaH" /GFF_Attribute="listLong" promotor_-35 complement(2031226..2031233) /Source="Nicolas_upshift_promotors" /id="U1509" /multdbtbs="SigD" /comp="M10" /sig="SigD" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=2825 /SigmaFactorBS="agaatttgcttattcatataagaatatcaCTATAAAActtga taacacgtGTCGATATTATGGACATGAgcgtaagcgaattggattcaaacgcgcttga a" /listShort="S694, yoaH" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 2031371..2031380 /Source="Nicolas_upshift_promotors" /id="U1510" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.971028971028971" /psig="0.971028971028971" /xcortree=1325 /SigmaFactorBS="cttattcgtttttctaaaaaaggcttttcccacctcaaattG GCTGAACCGgctgttttctcgAAAATATAATACAATACGCAgcataatatgaaggagc g" /listShort="yoaI" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 2031390 /Source="Nicolas_upshifts" /id="U1510" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.971028971028971" /psig="0.971028971028971" /xcortree=1325 /SigmaFactorBS="cttattcgtttttctaaaaaaggcttttcccacctcaaattG GCTGAACCGgctgttttctcgAAAATATAATACAATACGCAgcataatatgaaggagc g" /listShort="yoaI" /GFF_Attribute="listLong" promotor_-10 2031393..2031412 /Source="Nicolas_upshift_promotors" /id="U1510" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.971028971028971" /psig="0.971028971028971" /xcortree=1325 /SigmaFactorBS="cttattcgtttttctaaaaaaggcttttcccacctcaaattG GCTGAACCGgctgttttctcgAAAATATAATACAATACGCAgcataatatgaaggagc g" /listShort="yoaI" /GFF_Attribute="listLong" /label="promotor_-10" CDS 2031439..2032890 /gene="yoaI" /locus_tag="BSU_18620" /old_locus_tag="BSU18620" /EC_number="1.14.14.9" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative 4-hydroxyphenylacetate-3-hydroxylase" /protein_id="NP_389743.2" /db_xref="EnsemblGenomes-Gn:BSU18620" /db_xref="EnsemblGenomes-Tr:CAB13754" /db_xref="GOA:C0SPC0" /db_xref="InterPro:IPR004925" /db_xref="InterPro:IPR009100" /db_xref="InterPro:IPR012687" /db_xref="InterPro:IPR024674" /db_xref="InterPro:IPR024719" /db_xref="InterPro:IPR036250" /db_xref="SubtiList:BG13480" /db_xref="UniProtKB/Swiss-Prot:C0SPC0" /translation="MGIINGKEFIDRLNKLENEIWYDGEKIKGNISEHPAFKGIIKTK SSLYELQTKDELIHEMTYCLPGDHNRIGLSYLQPKTKNDLKKRRTMIEHWARHTHGMM GRSPDYMNTVMMSFASSAELLKDKENCFPEHILDMYEQAAKHDLSFTHTFITPQVNRS QSYFGLSEKPISAKVIDRTEKGLMIHGARLLATQGGLTDEILVFSAPKFFFETDEAYA FSIPSNTKGVKFITRESFVLSDSSFNHPLSSRYEEMDSIVVFDHVLVPWNRVFFYDNV EAAKDFMTKSSFHAFTFHQVVIRQMIKIEFLLGVAQLLVDTINVSEYQHIQEKLSEII VGLETIKALIDKSENDAQLDEFGYMRPCLIPLQVISTIIPKLYPRFTEIIQLIGASGM VTLPTENAFDSEIREDLDQYLQATNTNAEERVKIFRLAWDLTMSSFGTRQTHYERYFF GDPIRISSRLYTSYPKQEQLNMIKTFLHADTEH*" gene 2031439..2032890 /gene="yoaI" /locus_tag="BSU_18620" /old_locus_tag="BSU18620" downshifts 2032866 /Source="Nicolas_upshifts" /id="D1022" /incds=0 /nref=1 /ntot=19 /MaxReadThrough="2.84304" /MaxDrop="2.93575" /score="2.7297367" /energy="-12" /TU="U1510" /idTUdmin="U1510" /TUdmin="-22" /isTUend="TRUE" CDS complement(2032927..2033625) /gene="exlX" /locus_tag="BSU_18630" /old_locus_tag="BSU18630" /function="16.5: Explore" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:12354229, 18971341, 26751268" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12354229, 18971341, 26751268; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="extracellular endoglucanase precursor (expansin)" /protein_id="NP_389744.1" /db_xref="EnsemblGenomes-Gn:BSU18630" /db_xref="EnsemblGenomes-Tr:CAB13755" /db_xref="GOA:O34918" /db_xref="InterPro:IPR009009" /db_xref="InterPro:IPR036749" /db_xref="InterPro:IPR036908" /db_xref="PDB:2BH0" /db_xref="PDB:3D30" /db_xref="PDB:4FER" /db_xref="PDB:4FFT" /db_xref="PDB:4FG2" /db_xref="PDB:4FG4" /db_xref="SubtiList:BG13481" /db_xref="UniProtKB/Swiss-Prot:O34918" /translation="MKKIMSAFVGMVLLTIFCFSPQASAAYDDLHEGYATYTGSGYSG GAFLLDPIPSDMEITAINPADLNYGGVKAALAGSYLEVEGPKGKTTVYVTDLYPEGAR GALDLSPNAFRKIGNMKDGKINIKWRVVKAPITGNFTYRIKEGSSRWWAAIQVRNHKY PVMKMEYEKDGKWINMEKMDYNHFVSTNLGTGSLKVRMTDIRGKVVKDTIPKLPESGT SKAYTVPGHVQFPE*" gene complement(2032927..2033625) /gene="exlX" /locus_tag="BSU_18630" /old_locus_tag="BSU18630" downshifts complement(2032942) /Source="Nicolas_upshifts" /id="D1023" /incds=0 /nref=6 /ntot=95 /MaxReadThrough="0.66874" /MaxDrop="3.60414" /score="1.1918692" /energy="-7.7" /TU="NA" /idTUdmin="U1511" /TUdmin=132 /isTUend="FALSE" promotor_-10 complement(2033660..2033679) /Source="Nicolas_upshift_promotors" /id="U1511" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.762237762237762" /psig="0.998001998001998" /xcortree=3161 /SigmaFactorBS="tagtgaatttgccttaaaatcaactatgaatctatttccTCT TTCAAaccagatggattgAGTCTTATAATGATAATGATtctcatttgaagtctggttt g" /listShort="exlX" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2033679) /Source="Nicolas_upshifts" /id="U1511" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.762237762237762" /psig="0.998001998001998" /xcortree=3161 /SigmaFactorBS="tagtgaatttgccttaaaatcaactatgaatctatttccTCT TTCAAaccagatggattgAGTCTTATAATGATAATGATtctcatttgaagtctggttt g" /listShort="exlX" /GFF_Attribute="listLong" S_feature complement(2033681..2033894) /Source="Nicolas_S_feature" /locus_tag="new_2033681_2033894_c" /HighExp="G135, H2O2, G150, G180, LBGstat, dia15, LBGtran, Paraq, LBGexp, C30" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="NA" /TUshortPSig="NA" /TUlongSig="NA" /TUlongPSig="NA" /label="S695" promotor_-35 complement(2033693..2033700) /Source="Nicolas_upshift_promotors" /id="U1511" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.762237762237762" /psig="0.998001998001998" /xcortree=3161 /SigmaFactorBS="tagtgaatttgccttaaaatcaactatgaatctatttccTCT TTCAAaccagatggattgAGTCTTATAATGATAATGATtctcatttgaagtctggttt g" /listShort="exlX" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2033895..2034572) /gene="yoaK" /locus_tag="BSU_18640" /old_locus_tag="BSU18640" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative membrane protein" /protein_id="NP_389745.1" /db_xref="EnsemblGenomes-Gn:BSU18640" /db_xref="EnsemblGenomes-Tr:CAB13756" /db_xref="GOA:O34343" /db_xref="InterPro:IPR010699" /db_xref="SubtiList:BG13482" /db_xref="UniProtKB/Swiss-Prot:O34343" /translation="MTAAAYRNTLLSLLCLTAGIVDVIGYLSLGHVFTANMTGNIVLL GLAIGKSIQVTVFNSLTALIGFICGVIIATLMVGKAENTLWPSAVTKALALEAFILFV FACLSFYRAFVPVHILIILMSISMGIQTTAAKKLGIAGISSTVLTGTLASLLEDISGR LFFKKQKKTFLRDTVLRALAIILYCVGAIIVALAEPDFYHFIIWVPIVLIFGIMMTAK LKLSGEK*" gene complement(2033895..2034572) /gene="yoaK" /locus_tag="BSU_18640" /old_locus_tag="BSU18640" S_feature complement(2034573..2037062) /Source="Nicolas_S_feature" /locus_tag="new_2034573_2037062_c" /HighExp="LBGstat, G135, H2O2, G180, LBGtran, G150, dia15, Paraq, S0, Diami" /AntisenseName="pelB" /AntisenseCor="0.19898265589133701" /AntisenseRegPval="-3" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S696" CDS 2034745..2035782 /gene="pelB" /locus_tag="BSU_18650" /old_locus_tag="BSU18650" /EC_number="4.2.2.10" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 1731776, 2018526, 2185758, 7764549, 22695924; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="endo-pectin lyase" /protein_id="NP_389746.1" /db_xref="EnsemblGenomes-Gn:BSU18650" /db_xref="EnsemblGenomes-Tr:CAB13757" /db_xref="GOA:O34819" /db_xref="InterPro:IPR002022" /db_xref="InterPro:IPR011050" /db_xref="InterPro:IPR012334" /db_xref="SubtiList:BG12643" /db_xref="UniProtKB/Swiss-Prot:O34819" /translation="MKRLCLWFTVFSLFLVLLPGKALGAVDFPNTSTNGLLGFAGNAK NEKGISKTGTTGGKNGQIVYIQSVNDLKTHLGGSTPKILVLQNDLSASAKTTVTIGSN KTLVGSYAKKTLKNIYLTTSSAFGNVIFQNLTFEHSPQINGNNDIQLYLDSGMNYWID HVTFSGHSYNASGSDLDKLVYIGKSADYITISNSKFANHKYGLILGYPDDSQHQYDGY PHMTIANNYFENLYVRGPGLMRYGYFHVKNNYSNNFNQAITIATKAKIYSEYNYFGKG SEKGGILDDKGTGYFKDIGSYPSLNKQTSPLTSWNPGSNYSYRVQTPEYTKEFVTKYA GSQSTTLVFGY*" gene 2034745..2035782 /gene="pelB" /locus_tag="BSU_18650" /old_locus_tag="BSU18650" promotor_-35 2035979..2035985 /Source="Nicolas_upshift_promotors" /id="U1512" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=880 /SigmaFactorBS="agtgaaaagaaatcattgttctgaaccTGTATTAaatgaacg atcgtcCCACAAACTACTtaaaaacccctaaaaaggatgatggatatgtgcggcaggt t" /listShort="yoaM" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2036000..2036011 /Source="Nicolas_upshift_promotors" /id="U1512" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=880 /SigmaFactorBS="agtgaaaagaaatcattgttctgaaccTGTATTAaatgaacg atcgtcCCACAAACTACTtaaaaacccctaaaaaggatgatggatatgtgcggcaggt t" /listShort="yoaM" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2036012 /Source="Nicolas_upshifts" /id="U1512" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=880 /SigmaFactorBS="agtgaaaagaaatcattgttctgaaccTGTATTAaatgaacg atcgtcCCACAAACTACTtaaaaacccctaaaaaggatgatggatatgtgcggcaggt t" /listShort="yoaM" /GFF_Attribute="listLong" CDS 2036039..2036722 /gene="yoaM" /locus_tag="BSU_18660" /old_locus_tag="BSU18660" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 23945014, 26070154; Product type f: factor" /codon_start=1 /transl_table=11 /product="putative SOS response associated protein; defective prophage 6" /protein_id="NP_389747.1" /db_xref="EnsemblGenomes-Gn:BSU18660" /db_xref="EnsemblGenomes-Tr:CAB13758" /db_xref="GOA:O34906" /db_xref="InterPro:IPR003738" /db_xref="InterPro:IPR036590" /db_xref="SubtiList:BG13483" /db_xref="UniProtKB/Swiss-Prot:O34906" /translation="MCGRFTLYSAFDDIIDQFDIDQFFPKGEYQPSYNVAPSQNILAI INDGSNNRLGKLRWGLIPPWAKDEKIGYKMINARAETITEKPAFRRPLVSKRCIIPAD SFYEWKRLDSKTKIPMRIKLKSSALFAFAGLYEKWSTHQGYPLYTCTIITTEPNEFMK DIHDRMPVILAHDHEKEWLNPKNTSPDYLQSLLLPYDADDMEAYQVSSLVNSPKNNSA ELLDAENHM*" gene 2036039..2036722 /gene="yoaM" /locus_tag="BSU_18660" /old_locus_tag="BSU18660" CDS complement(2037063..2037368) /gene="yozS" /locus_tag="BSU_18669" /old_locus_tag="BSU18669" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative permease, phage-related; defective prophage 6" /protein_id="YP_003097734.1" /db_xref="EnsemblGenomes-Gn:BSU18669" /db_xref="EnsemblGenomes-Tr:CAX52628" /db_xref="GOA:C0H420" /db_xref="UniProtKB/Swiss-Prot:C0H420" /translation="MKALIFLSSLTAIGSSILGRWLGMLDDSYAVGDAWFIGVLAGLI SLLILIDSQTMTKNYIVSLSTILGILGVGFIYFPAAFINILLSITLDKQKKEDLHVR* " gene complement(2037063..2037368) /gene="yozS" /locus_tag="BSU_18669" /old_locus_tag="BSU18669" S_feature complement(2037369..2037470) /Source="Nicolas_S_feature" /locus_tag="new_2037369_2037470_c" /HighExp="HiTm, LBGstat, LBGtran, T1.30H, T1.0H, T0.30H, M9-stat, Lbstat, M0t90, T2.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S697" promotor_-10 complement(2037449..2037468) /Source="Nicolas_upshift_promotors" /id="U1513" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.725274725274725" /psig=1 /xcortree=3228 /SigmaFactorBS="tttattaaatccctatatatacgttatgtagggtttttctGC TTGAATcgtattgtaatgagCTTTAAAATGTTAATGTGGAaatgaaatggtaaccatt c" /listShort="S697, yozS, S696" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2037470) /Source="Nicolas_upshifts" /id="U1513" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.725274725274725" /psig=1 /xcortree=3228 /SigmaFactorBS="tttattaaatccctatatatacgttatgtagggtttttctGC TTGAATcgtattgtaatgagCTTTAAAATGTTAATGTGGAaatgaaatggtaaccatt c" /listShort="S697, yozS, S696" /GFF_Attribute="listLong" promotor_-35 complement(2037483..2037490) /Source="Nicolas_upshift_promotors" /id="U1513" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.725274725274725" /psig=1 /xcortree=3228 /SigmaFactorBS="tttattaaatccctatatatacgttatgtagggtttttctGC TTGAATcgtattgtaatgagCTTTAAAATGTTAATGTGGAaatgaaatggtaaccatt c" /listShort="S697, yozS, S696" /GFF_Attribute="listLong" /label="promotor_-35" S_feature complement(2037498..2037600) /Source="Nicolas_S_feature" /locus_tag="new_2037498_2037600_c" /HighExp="S8, S6, S7, S5, BT, G/S, Pyr, B36, nit, SMMPr" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigK" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S698" downshifts complement(2037540) /Source="Nicolas_upshifts" /id="D1024" /incds=0 /nref=9 /ntot=21 /MaxReadThrough="1.67639" /MaxDrop="3.95763" /score="-5.39979801" /energy="-8.3" /TU="NA" /idTUdmin="U1514" /TUdmin=0 /isTUend="TRUE" CDS complement(2037601..2038779) /gene="oxdD" /locus_tag="BSU_18670" /old_locus_tag="BSU18670" /EC_number="4.1.1.2" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:11546787, 14697267, 14973022, 15628860, 25526893" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11546787, 14697267, 14973022, 15628860, 25526893; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="oxalate decarboxylase (Mn2+-dependent); spore constituent" /protein_id="NP_389748.1" /db_xref="EnsemblGenomes-Gn:BSU18670" /db_xref="EnsemblGenomes-Tr:CAB13759" /db_xref="GOA:O34767" /db_xref="InterPro:IPR006045" /db_xref="InterPro:IPR011051" /db_xref="InterPro:IPR014710" /db_xref="InterPro:IPR017774" /db_xref="SubtiList:BG13484" /db_xref="UniProtKB/Swiss-Prot:O34767" /translation="MLLEQQPINHEDRNVPQPIRSDGAGAIDTGPRNIIRDIQNPNIF VPPVTDEGMIPNLRFSFSDAPMKLDHGGWSREITVRQLPISTAIAGVNMSLTAGGVRE LHWHKQAEWAYMLLGRARITAVDQDGRNFIADVGPGDLWYFPAGIPHSIQGLEHCEFL LVFDDGNFSEFSTLTISDWLAHTPKDVLSANFGVPENAFNSLPSEQVYIYQGNVPGSV ASEDIQSPYGKVPMTFKHELLNQPPIQMPGGSVRIVDSSNFPISKTIAAALVQIEPGA MRELHWHPNSDEWQYYLTGQGRMTVFIGNGTARTFDYRAGDVGYVPSNAGHYIQNTGT ETLWFLEMFKSNRYADVSLNQWMALTPKELVQSNLNAGSVMLDSLRKKKVPVVKYPGT *" gene complement(2037601..2038779) /gene="oxdD" /locus_tag="BSU_18670" /old_locus_tag="BSU18670" promotor_-10 complement(2038805..2038824) /Source="Nicolas_upshift_promotors" /id="U1514" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1289 /SigmaFactorBS="tgatcacattggtggtcacttttttatttgcggattcCTAGG CACAGcaatctaagattcTGCATAGGCTGAAATAAAATcttgttcatttctaaaacga g" /listShort="yoaN, S698" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2038824) /Source="Nicolas_upshifts" /id="U1514" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1289 /SigmaFactorBS="tgatcacattggtggtcacttttttatttgcggattcCTAGG CACAGcaatctaagattcTGCATAGGCTGAAATAAAATcttgttcatttctaaaacga g" /listShort="yoaN, S698" /GFF_Attribute="listLong" promotor_-35 complement(2038838..2038847) /Source="Nicolas_upshift_promotors" /id="U1514" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1289 /SigmaFactorBS="tgatcacattggtggtcacttttttatttgcggattcCTAGG CACAGcaatctaagattcTGCATAGGCTGAAATAAAATcttgttcatttctaaaacga g" /listShort="yoaN, S698" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2038902..2039390) /gene="yoaO" /locus_tag="BSU_18680" /old_locus_tag="BSU18680" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_389749.1" /db_xref="EnsemblGenomes-Gn:BSU18680" /db_xref="EnsemblGenomes-Tr:CAB13760" /db_xref="InterPro:IPR032545" /db_xref="SubtiList:BG13485" /db_xref="UniProtKB/Swiss-Prot:O34985" /translation="MRKKNNIKKWLLIIAGFLIICIITLFVMVSGNKVKYEGSGKSGL WMSNLEKSDKTSIGPNYFLNLYWQGSKKEEKWTVVERITLYVDGEKYQDDNVDEYDLS EYTGDEMPGGGRMEDHISTFDYMPEDEVIGHDVLVKVEWRTGQKKQTEAIKLHKKPWY KK*" gene complement(2038902..2039390) /gene="yoaO" /locus_tag="BSU_18680" /old_locus_tag="BSU18680" downshifts complement(2038927) /Source="Nicolas_upshifts" /id="D1025" /incds=0 /nref=32 /ntot=201 /MaxReadThrough="0.50319" /MaxDrop="3.84714" /score="18.561323" /energy="-9.2" /TU="NA" /idTUdmin="U1514" /TUdmin="-1387" /isTUend="FALSE" CDS complement(2039415..2039570) /locus_tag="BSU_18689" /old_locus_tag="BSU18689" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_009513964.1" /translation="MKQKMHLRAVIRFNLVFRKHFNLSQKFRQSSVRSLALSYFLFGN ILIVFSY*" gene complement(2039415..2039570) /locus_tag="BSU_18689" /old_locus_tag="BSU18689" CDS complement(2039610..2040365) /gene="yoaP" /locus_tag="BSU_18690" /old_locus_tag="BSU18690" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_389750.1" /db_xref="EnsemblGenomes-Gn:BSU18690" /db_xref="EnsemblGenomes-Tr:CAB13761" /db_xref="GOA:O34983" /db_xref="InterPro:IPR000182" /db_xref="InterPro:IPR016181" /db_xref="InterPro:IPR025685" /db_xref="InterPro:IPR036249" /db_xref="SubtiList:BG13486" /db_xref="UniProtKB/Swiss-Prot:O34983" /translation="MCYIEITKDNIEDNHICCALSTKQYEHAVNEKKRWLKARMDEGL VFYRLHERAKVFIEYLPANEAWVPINAPNFMYINCLWVSGRYKNNGHAKRLLDKCIAD AKACGMDGIIHIAGKKKLPYLSDKHFFEHMGFTLQDEAAPYFQLMALTWNGLADSPAF KSQVKSDSINEKGITIYYTAQCPFAVGMINDLRELTEKKGVQFQSIQLSSKEEAQKSP AIWTTFSVFFDGRFVTHEIMSINKFEKLLNTLA*" gene complement(2039610..2040365) /gene="yoaP" /locus_tag="BSU_18690" /old_locus_tag="BSU18690" promotor_-35 2040618..2040623 /Source="Nicolas_upshift_promotors" /id="U1515" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.993006993006993" /psig="0.993006993006993" /xcortree=1037 /SigmaFactorBS="agtacacgaagttttttatttgaaGTAATAtttgttacggga cagCAATAGTAAATAAGTGATAaaaggggaattaaacttggtggaaaaatgttattct t" /listShort="yoaQ, S699" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2040639..2040657 /Source="Nicolas_upshift_promotors" /id="U1515" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.993006993006993" /psig="0.993006993006993" /xcortree=1037 /SigmaFactorBS="agtacacgaagttttttatttgaaGTAATAtttgttacggga cagCAATAGTAAATAAGTGATAaaaggggaattaaacttggtggaaaaatgttattct t" /listShort="yoaQ, S699" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2040654 /Source="Nicolas_upshifts" /id="U1515" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.993006993006993" /psig="0.993006993006993" /xcortree=1037 /SigmaFactorBS="agtacacgaagttttttatttgaaGTAATAtttgttacggga cagCAATAGTAAATAAGTGATAaaaggggaattaaacttggtggaaaaatgttattct t" /listShort="yoaQ, S699" /GFF_Attribute="listLong" CDS 2040673..2041029 /gene="yoaQ" /locus_tag="BSU_18700" /old_locus_tag="BSU18700" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_389751.1" /db_xref="EnsemblGenomes-Gn:BSU18700" /db_xref="EnsemblGenomes-Tr:CAB13762" /db_xref="SubtiList:BG13487" /db_xref="UniProtKB/Swiss-Prot:O31831" /translation="MVEKCYSCLICGYKGLIQNPLYKGEYQKTFDICPCCGFEFGYSE DHDVRLGFIVTPDHLIEAAFQLYRKQWLESGMVIAHPEDIPEELKNGNCLKFEVLLKQ LKKLNLDIENFEISGF*" gene 2040673..2041029 /gene="yoaQ" /locus_tag="BSU_18700" /old_locus_tag="BSU18700" CDS complement(2040988..2041227) /gene="yozT" /locus_tag="BSU_18709" /old_locus_tag="BSU18709" /function="18: Unknown function" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein (putative phage origin); putative defective prophage 6" /protein_id="YP_003097735.1" /db_xref="EnsemblGenomes-Gn:BSU18709" /db_xref="EnsemblGenomes-Tr:CAX52629" /db_xref="UniProtKB/Swiss-Prot:C0H421" /translation="MTVINDYREEPEEAFWILYPMGVKCLSMITKSLLNTNRDFVTDC AFQLNILLIMTVKPKQVQPVSSLKTANFKIFYVKI*" gene complement(2040988..2041227) /gene="yozT" /locus_tag="BSU_18709" /old_locus_tag="BSU18709" S_feature 2041030..2041466 /Source="Nicolas_S_feature" /locus_tag="new_2041030_2041466" /HighExp="S8, S7, S4, S5, S6, S3, T5.0H, LoTm, BT, T4.0H" /AntisenseName="yozT" /AntisenseCor="0.93420248567111996" /AntisenseRegPval="-120.8" /CDS_PredictionProba="NA" /TUshortSig="SigEF" /TUshortPSig="0.993" /TUlongSig="NA" /TUlongPSig="NA" /label="S699" S_feature complement(2041228..2041329) /Source="Nicolas_S_feature" /locus_tag="new_2041228_2041329_c" /HighExp="S8, S7, S6, S5, S4, BT, ferm, nit, S3, T5.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigGF" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S700" CDS complement(2041330..2041827) /gene="yozF" /locus_tag="BSU_18710" /old_locus_tag="BSU18710" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type lp: lipoprotein" /codon_start=1 /transl_table=11 /product="putative lipoprotein" /protein_id="NP_389752.2" /db_xref="EnsemblGenomes-Gn:BSU18710" /db_xref="EnsemblGenomes-Tr:CAB13763" /db_xref="SubtiList:BG13753" /db_xref="UniProtKB/Swiss-Prot:O31832" /translation="MKRVLFSVIVFTAVGFTFCQSKAHALTFTVLPITQKTDQWSVKV SEAKNVKEFTRPHKGEYQVYSLEVKNIGEKAATVDVQLYRNDPNSITRFSLFGCPDEN CVKPKEDSKMLAESLNDGSPLKFNHFMLADKASELEVVIIWTQKGQEGRNLKQTFKFT EDGVN*" gene complement(2041330..2041827) /gene="yozF" /locus_tag="BSU_18710" /old_locus_tag="BSU18710" S_feature complement(2041828..2041927) /Source="Nicolas_S_feature" /locus_tag="new_2041828_2041927_c" /HighExp="S8, S7, S5, S6, S4, BT, ferm, nit, S3, T5.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigGF" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S701" CDS complement(2041928..2042839) /gene="yoaR" /locus_tag="BSU_18720" /old_locus_tag="BSU18720" /function="16.8: Protect" /function="16.13: Shape" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 8631706; Product type f: factor" /codon_start=1 /transl_table=11 /product="putative factor for cell wall maintenance or synthesis" /protein_id="NP_389753.1" /db_xref="EnsemblGenomes-Gn:BSU18720" /db_xref="EnsemblGenomes-Tr:CAB13764" /db_xref="InterPro:IPR007391" /db_xref="SubtiList:BG13488" /db_xref="UniProtKB/Swiss-Prot:O34611" /translation="MIQILITGLFLLAQPSEPQDSLTVTQQGRTIATVNREDFTMPLP GTPMVDYEKYSKFIKQLDQKVYREPINAVLNDHGSIVPGRVGYKLYQQAFMEKFYAYF YGQGPSKIEVPEMNIYPKVDSELLAHISTQQLGQYVTYFNSSNKSRSHNISLSAKAID NHVVFPNETFSFNQVVGMRTRNKGYKSAPIIVKGELSEGVGGGICQVSSTLFNAVDRA GLQIVQRYSHTRSVPYVPPGRDATVSWGGPDFRFQNQYNQPILIRAKRYGGSMIITLY SSDVINSRLRKIPKAPSRIPKEINAEQ*" gene complement(2041928..2042839) /gene="yoaR" /locus_tag="BSU_18720" /old_locus_tag="BSU18720" promotor_-10 complement(2042861..2042872) /Source="Nicolas_upshift_promotors" /id="U1516" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=941 /SigmaFactorBS="ctaaagattcaaacaaacgatgggaagaaaTACATCAaagga taagcggctGTTCATACTAATgattgggaggtaaaccgacttatgatacaaattttga t" /listShort="yoaR, S701, yozF, S700, yozT" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2042863) /Source="Nicolas_upshifts" /id="U1516" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=941 /SigmaFactorBS="ctaaagattcaaacaaacgatgggaagaaaTACATCAaagga taagcggctGTTCATACTAATgattgggaggtaaaccgacttatgatacaaattttga t" /listShort="yoaR, S701, yozF, S700, yozT" /GFF_Attribute="listLong" promotor_-35 complement(2042887..2042893) /Source="Nicolas_upshift_promotors" /id="U1516" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=941 /SigmaFactorBS="ctaaagattcaaacaaacgatgggaagaaaTACATCAaagga taagcggctGTTCATACTAATgattgggaggtaaaccgacttatgatacaaattttga t" /listShort="yoaR, S701, yozF, S700, yozT" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 2043123..2043130 /Source="Nicolas_upshift_promotors" /id="U1517" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.906093906093906" /psig="0.999000999001" /xcortree=2172 /SigmaFactorBS="ggtctcctataacaacaaaaaatcaatccatttcaatatttt ttTATTGAGAaacgataaatttttTGTTACATTCAATTAGACAAcaaataaatgaggt g" /listShort="yoaS, yozG, S702, yoaT, S703" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 2043139 /Source="Nicolas_upshifts" /id="U1517" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.906093906093906" /psig="0.999000999001" /xcortree=2172 /SigmaFactorBS="ggtctcctataacaacaaaaaatcaatccatttcaatatttt ttTATTGAGAaacgataaatttttTGTTACATTCAATTAGACAAcaaataaatgaggt g" /listShort="yoaS, yozG, S702, yoaT, S703" /GFF_Attribute="listLong" promotor_-10 2043145..2043164 /Source="Nicolas_upshift_promotors" /id="U1517" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.906093906093906" /psig="0.999000999001" /xcortree=2172 /SigmaFactorBS="ggtctcctataacaacaaaaaatcaatccatttcaatatttt ttTATTGAGAaacgataaatttttTGTTACATTCAATTAGACAAcaaataaatgaggt g" /listShort="yoaS, yozG, S702, yoaT, S703" /GFF_Attribute="listLong" /label="promotor_-10" CDS 2043186..2043668 /gene="yoaS" /locus_tag="BSU_18730" /old_locus_tag="BSU18730" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406, 19493340; Product type f: factor" /codon_start=1 /transl_table=11 /product="putative toxin of a toxin / antitoxin system" /protein_id="NP_389754.1" /db_xref="EnsemblGenomes-Gn:BSU18730" /db_xref="EnsemblGenomes-Tr:CAB13765" /db_xref="GOA:O31833" /db_xref="InterPro:IPR021354" /db_xref="SubtiList:BG13489" /db_xref="UniProtKB/Swiss-Prot:O31833" /translation="MNRMSTIFLKIALVLIGIPILALCIFLVPKVANYSAELFPNIAY IKYLVFIYLYVTAIPFYFALYQAFKLLSYIDKNKAFSGLSVRALKNIKYCAVTISIFY AAGMPVFYLMAEIDDAPGIIVIGLVIIFASMVIAVFAAVLQKLLKEAIDIKSENDLTV *" gene 2043186..2043668 /gene="yoaS" /locus_tag="BSU_18730" /old_locus_tag="BSU18730" CDS 2043678..2043932 /gene="yozG" /locus_tag="BSU_18740" /old_locus_tag="BSU18740" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 19493340; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative antitoxin of a toxin / antitoxin system; putative transcriptional regulator" /protein_id="NP_389755.1" /db_xref="EnsemblGenomes-Gn:BSU18740" /db_xref="EnsemblGenomes-Tr:CAB13766" /db_xref="GOA:O31834" /db_xref="InterPro:IPR001387" /db_xref="InterPro:IPR010982" /db_xref="SubtiList:BG13754" /db_xref="UniProtKB/Swiss-Prot:O31834" /translation="MAIIINIDVMLAKRKMSVTELSERVGITMANLSILKNGKAKAIR LSTLEAICKALECQPGDILEYRSDEDTGFVKKKYEGSTEK*" gene 2043678..2043932 /gene="yozG" /locus_tag="BSU_18740" /old_locus_tag="BSU18740" S_feature 2043933..2044037 /Source="Nicolas_S_feature" /locus_tag="new_2043933_2044037" /HighExp="LoTm, B60, Sw, G135, G180, B36, LBGstat, Cold, LBGtran, T2.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S702" CDS 2044038..2044832 /gene="yoaT" /locus_tag="BSU_18750" /old_locus_tag="BSU18750" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative integral inner membrane protein" /protein_id="NP_389756.1" /db_xref="EnsemblGenomes-Gn:BSU18750" /db_xref="EnsemblGenomes-Tr:CAB13767" /db_xref="GOA:O34535" /db_xref="InterPro:IPR008535" /db_xref="SubtiList:BG13490" /db_xref="UniProtKB/Swiss-Prot:O34535" /translation="MRAIKQIVHFGWEQALSCLFPAVIFASLAITQIIPLPFLPRYDW LLIICVLMQLWMVRSGLETRDELKVITLFHLIGLALELFKVHMGSWSYPEEGYSKIFG VPLYSGFMYASVASYLCQAWRRLKVELVKWPSFFAVVPLAAAIYLNFFTHHFSIDIRW WLSGLVIIVFWQTWVTYEVNGARYRMPLALSFILIGFFIWIAENIATFFGAWKYPNQI DTWSLVHLGKVSSWLLLVIVSFLIVASLKQVKEQSPTKAEMDESFS*" gene 2044038..2044832 /gene="yoaT" /locus_tag="BSU_18750" /old_locus_tag="BSU18750" S_feature 2044833..2045843 /Source="Nicolas_S_feature" /locus_tag="new_2044833_2045843" /HighExp="LoTm, Cold, Sw, H2O2, B60, GM 10, S8, dia15, T2.30H, MG 60" /AntisenseName="yoaU" /AntisenseCor="-2.6976304882719598E-2" /AntisenseRegPval="-0.2" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S703" CDS complement(2044956..2045828) /gene="yoaU" /locus_tag="BSU_18760" /old_locus_tag="BSU18760" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 17526699; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative transcriptional regulator (LysR family)" /protein_id="NP_389757.1" /db_xref="EnsemblGenomes-Gn:BSU18760" /db_xref="EnsemblGenomes-Tr:CAB13768" /db_xref="GOA:O34701" /db_xref="InterPro:IPR000847" /db_xref="InterPro:IPR005119" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG13491" /db_xref="UniProtKB/Swiss-Prot:O34701" /translation="MVMNMNHLHIFVKVGEKLNITEAAKELFISQPAVSKAIKNLESS LQLKLLIRDKHHGLMLTDIGKEILLLARQMKGIESKIYQVANRENKLLNGKVKIGSFP AVSTNIMPQAIAAFRSNYPLIRIELIEGTSDQIKGWVEDRTVDIGIAASPFEPFENQL LCNDYMVAVIPPQRDELKLEKHVDLETYQDDLIFCKGGHEIAMSNAFSQYNIELKENL TVQNAETLINMVKNNLGIGIISNFTLSSVPHQLIKKDIFPRVTRDIGVIAHSFEEITP AAHEFVKVLKAVVI*" gene complement(2044956..2045828) /gene="yoaU" /locus_tag="BSU_18760" /old_locus_tag="BSU18760" CDS 2045929..2046807 /gene="yoaV" /locus_tag="BSU_18770" /old_locus_tag="BSU18770" /function="16.1: Circulate" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 10844694, 11717295, 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative modified amino acid or TCA compound efflux permease" /protein_id="NP_389758.1" /db_xref="EnsemblGenomes-Gn:BSU18770" /db_xref="EnsemblGenomes-Tr:CAB13769" /db_xref="GOA:O34416" /db_xref="InterPro:IPR000620" /db_xref="SubtiList:BG13492" /db_xref="UniProtKB/Swiss-Prot:O34416" /translation="MVKVMLGIISVTLIWGYTWVAMKVGIHDIPPLLFSGLRLFIGAV PLFLILFIQRKKLSIQKEHLKSYIIMSLLMGLGYMGILTYGMQFVDSGKTSVLVYTMP IFVTVISHFSLNEKMNVYKTMGLVCGLFGLLFIFGKEMLNIDQSALFGELCVLVAALS WGIANVFSKLQFKHIDIIHMNAWHLMMGAVMLLVFSFIFEAVPSAEWTYQAVWSLLFN GLLSTGFTFVVWFWVLNQIQASKASMALMFVPVLALFFGWLQLHEQITINIILGALLI CCGIFMNTFTFSRRKV*" gene 2045929..2046807 /gene="yoaV" /locus_tag="BSU_18770" /old_locus_tag="BSU18770" S_feature complement(2046920..2046979) /Source="Nicolas_S_feature" /locus_tag="new_2046920_2046979_c" /HighExp="BC, T4.0H, M9-stat, S5, T5.0H, S4, S3, T3.0H, T3.30H, BT" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.167154" /TUshortSig="NA" /TUshortPSig="NA" /TUlongSig="NA" /TUlongPSig="NA" /label="S704" downshifts complement(2046955) /Source="Nicolas_upshifts" /id="D1026" /incds=0 /nref=55 /ntot=175 /MaxReadThrough="1.78313" /MaxDrop="5.17096" /score="15.465237" /energy="-12.3" /TU="NA" /idTUdmin="U1518" /TUdmin=0 /isTUend="TRUE" CDS complement(2046980..2047411) /gene="yoaW" /locus_tag="BSU_18780" /old_locus_tag="BSU18780" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:15101989" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15101989; Product type ph: phenotype" /codon_start=1 /transl_table=11 /product="biofilm forming exported protein" /protein_id="NP_389759.1" /db_xref="EnsemblGenomes-Gn:BSU18780" /db_xref="EnsemblGenomes-Tr:CAB13770" /db_xref="SubtiList:BG13493" /db_xref="UniProtKB/Swiss-Prot:O34541" /translation="MKKMLMLAFTFLLALTIHVGEASAVIVKDEEKVSFTMTENEKWF MKSDDLNSNHWTSHFGYRFTIFDTEGCTINARIMRMTLSGYEITVSEKNFSGDHFDFS ATDRVETMPYKTHYLILTKDPDCGDVKVKGLYGFQFDQPEW*" gene complement(2046980..2047411) /gene="yoaW" /locus_tag="BSU_18780" /old_locus_tag="BSU18780" promotor_-10 complement(2047431..2047450) /Source="Nicolas_upshift_promotors" /id="U1518" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.432567432567433" /psig=1 /xcortree=485 /SigmaFactorBS="ggtgctaaagattcatttggagaagactgTCTTGATcagaaa agaccctTCCAATATATTGAAGTAAAAgatatcgggaggaactcttttgaaaaagatg t" /listShort="yoaW" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2047439) /Source="Nicolas_upshifts" /id="U1518" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.432567432567433" /psig=1 /xcortree=485 /SigmaFactorBS="ggtgctaaagattcatttggagaagactgTCTTGATcagaaa agaccctTCCAATATATTGAAGTAAAAgatatcgggaggaactcttttgaaaaagatg t" /listShort="yoaW" /GFF_Attribute="listLong" S_feature complement(2047441..2047674) /Source="Nicolas_S_feature" /locus_tag="new_2047441_2047674_c" /HighExp="S4, S3, S5, S7, S8, S6, LoTm, T5.0H, T4.0H, Pyr" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigEF" /TUshortPSig="0.998" /TUlongSig="NA" /TUlongPSig="NA" /label="S705" promotor_-35 complement(2047464..2047470) /Source="Nicolas_upshift_promotors" /id="U1518" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.432567432567433" /psig=1 /xcortree=485 /SigmaFactorBS="ggtgctaaagattcatttggagaagactgTCTTGATcagaaa agaccctTCCAATATATTGAAGTAAAAgatatcgggaggaactcttttgaaaaagatg t" /listShort="yoaW" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(2047675..2047693) /Source="Nicolas_upshift_promotors" /id="U1519" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=1172 /SigmaFactorBS="gtataagctaaataagactcaaaagccTGAATAtttctttga gctaatGAATACAATAAATCGATAGaaaacactttagcagttttttgtagtgctcctg a" /listShort="S705, yoaW" /GFF_Attribute="listLong" /label="promotor_-10" CDS complement(2047675..2048307) /gene="yoaZ" /locus_tag="BSU_18790" /old_locus_tag="BSU18790" /function="16.6: Maintain" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 16181642; Product type f: factor" /codon_start=1 /transl_table=11 /product="putative factor of the oxidative stress response" /protein_id="NP_389760.1" /db_xref="EnsemblGenomes-Gn:BSU18790" /db_xref="EnsemblGenomes-Tr:CAB13771" /db_xref="GOA:O34947" /db_xref="InterPro:IPR002818" /db_xref="InterPro:IPR029062" /db_xref="SubtiList:BG13494" /db_xref="UniProtKB/Swiss-Prot:O34947" /translation="MQTRKVYLYVFHTMSDWEYGYLIAELNSGRYFKQDAASLKVVTV GVNKEMITTLGGLSIKPDISLDECTLGSQDLIILPGGNTWGEDIHQPILKKVGDALKL GTTIAAICGATLGLANEGYLNSRKHTSNDLDYMNMVCPNYKGETFYEKGPAVSDENLV TASGIAPLEFAVEVLKKLDVFAPDTLRSWYKLNKTQKPEYFFELMNTINR*" gene complement(2047675..2048307) /gene="yoaZ" /locus_tag="BSU_18790" /old_locus_tag="BSU18790" upshifts complement(2047681) /Source="Nicolas_upshifts" /id="U1519" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=1172 /SigmaFactorBS="gtataagctaaataagactcaaaagccTGAATAtttctttga gctaatGAATACAATAAATCGATAGaaaacactttagcagttttttgtagtgctcctg a" /listShort="S705, yoaW" /GFF_Attribute="listLong" promotor_-35 complement(2047709..2047714) /Source="Nicolas_upshift_promotors" /id="U1519" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=1172 /SigmaFactorBS="gtataagctaaataagactcaaaagccTGAATAtttctttga gctaatGAATACAATAAATCGATAGaaaacactttagcagttttttgtagtgctcctg a" /listShort="S705, yoaW" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 2048445..2048452 /Source="Nicolas_upshift_promotors" /id="U1520" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.84015984015984" /psig="0.999000999001" /xcortree=3062 /SigmaFactorBS="ccaacttataaaaatataagatcaattgattctaTGTTTACT agcgcaaaggggttTGTTACACTAACTGTCATGGgaaacatttcaaaggtaatacaaa a" /listShort="penP, S706" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2048467..2048486 /Source="Nicolas_upshift_promotors" /id="U1520" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.84015984015984" /psig="0.999000999001" /xcortree=3062 /SigmaFactorBS="ccaacttataaaaatataagatcaattgattctaTGTTTACT agcgcaaaggggttTGTTACACTAACTGTCATGGgaaacatttcaaaggtaatacaaa a" /listShort="penP, S706" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2048471 /Source="Nicolas_upshifts" /id="U1520" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.84015984015984" /psig="0.999000999001" /xcortree=3062 /SigmaFactorBS="ccaacttataaaaatataagatcaattgattctaTGTTTACT agcgcaaaggggttTGTTACACTAACTGTCATGGgaaacatttcaaaggtaatacaaa a" /listShort="penP, S706" /GFF_Attribute="listLong" CDS 2048533..2049453 /gene="penP" /locus_tag="BSU_18800" /old_locus_tag="BSU18800" /EC_number="3.5.2.6" /function="16.5: Explore" /function="16.8: Protect" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 7789815, 15187182, 16944130, 22211522, 25112476, 25355936; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="beta-lactamase precursor (putative hydrolase)" /protein_id="NP_389761.1" /db_xref="EnsemblGenomes-Gn:BSU18800" /db_xref="EnsemblGenomes-Tr:CAB13772" /db_xref="GOA:P39824" /db_xref="InterPro:IPR000871" /db_xref="InterPro:IPR012338" /db_xref="InterPro:IPR023650" /db_xref="SubtiList:BG11016" /db_xref="UniProtKB/Swiss-Prot:P39824" /translation="MKLKTKASIKFGICVGLLCLSITGFTPFFNSTHAEAKSIEDTNM ASCITNKKFVQLEKKFDARLGVYAIDIGSNKTIAYRPNERFAYASTYKVLAAAAVLKK NSIEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLG GPKGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTT DKRMILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVV AILSNRFTKDANYDNALIAEAAKVVLNDLK*" gene 2048533..2049453 /gene="penP" /locus_tag="BSU_18800" /old_locus_tag="BSU18800" promotor_-10 complement(2048964..2048983) /Source="Nicolas_upshift_promotors" /id="U1521" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.744255744255744" /psig="0.995004995004995" /xcortree=426 /SigmaFactorBS="cagtgacttttcaaaacctttagggccgccaagcTGTTGCAA caagatgttcccagCGGTATTATCGCTGTAACGGatagccgcttccgagatttctttt a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2048979) /Source="Nicolas_upshifts" /id="U1521" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.744255744255744" /psig="0.995004995004995" /xcortree=426 /SigmaFactorBS="cagtgacttttcaaaacctttagggccgccaagcTGTTGCAA caagatgttcccagCGGTATTATCGCTGTAACGGatagccgcttccgagatttctttt a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(2048998..2049005) /Source="Nicolas_upshift_promotors" /id="U1521" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.744255744255744" /psig="0.995004995004995" /xcortree=426 /SigmaFactorBS="cagtgacttttcaaaacctttagggccgccaagcTGTTGCAA caagatgttcccagCGGTATTATCGCTGTAACGGatagccgcttccgagatttctttt a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" S_feature 2049454..2050111 /Source="Nicolas_S_feature" /locus_tag="new_2049454_2050111" /HighExp="HiOs, S8, GM 25, GM 15, GM-0.1, C30, S2, S1, BC, GM 45" /AntisenseName="yobA" /AntisenseCor="8.9918765131424994E-2" /AntisenseRegPval="-0.8" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S706" CDS complement(2049950..2050312) /gene="yobA" /locus_tag="BSU_18810" /old_locus_tag="BSU18810" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="NP_389762.1" /db_xref="EnsemblGenomes-Gn:BSU18810" /db_xref="EnsemblGenomes-Tr:CAB13773" /db_xref="InterPro:IPR021598" /db_xref="PDB:2JQO" /db_xref="PDB:4QY7" /db_xref="SubtiList:BG13495" /db_xref="UniProtKB/Swiss-Prot:O31835" /translation="MPKIGVSLIVLIMLIIFLAGCNKNEQNGDETKMQSLVGYVVLKD NERAILITDTKAPGKEDYNLSEGQLMNKFKNNIVIVGLSEIDNTDDLKRGEKIKVWFH TRKESNPPSATIQKYELL*" gene complement(2049950..2050312) /gene="yobA" /locus_tag="BSU_18810" /old_locus_tag="BSU18810" CDS complement(2050373..2050585) /gene="yozU" /locus_tag="BSU_18819" /old_locus_tag="BSU18819" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function; Product type h : extrachromosomal origin" /pseudo /codon_start=1 /transl_table=11 /product="putative phage protein" /db_xref="PSEUDO:CAX52630.1" /translation="MEVAIVNDSKDKYIYAGIQKEAAFNNIFESAKMSKRIISRATTC KYLRKNKKKVEELENEYAAVMNCKKK*" gene complement(2050373..2050585) /gene="yozU" /locus_tag="BSU_18819" /old_locus_tag="BSU18819" /pseudo promotor_-35 2050624..2050631 /Source="Nicolas_upshift_promotors" /id="U1522" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.625374625374625" /psig="0.967032967032967" /xcortree=487 /SigmaFactorBS="aatcgagatttttactttttttatgatccattattCACTTCC AaaataacttccaatTACAACATAATATATGTATAaattgtaaatggagttgatgtaa t" /listShort="yobB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2050646..2050665 /Source="Nicolas_upshift_promotors" /id="U1522" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.625374625374625" /psig="0.967032967032967" /xcortree=487 /SigmaFactorBS="aatcgagatttttactttttttatgatccattattCACTTCC AaaataacttccaatTACAACATAATATATGTATAaattgtaaatggagttgatgtaa t" /listShort="yobB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2050649 /Source="Nicolas_upshifts" /id="U1522" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.625374625374625" /psig="0.967032967032967" /xcortree=487 /SigmaFactorBS="aatcgagatttttactttttttatgatccattattCACTTCC AaaataacttccaatTACAACATAATATATGTATAaattgtaaatggagttgatgtaa t" /listShort="yobB" /GFF_Attribute="listLong" CDS 2050689..2050952 /gene="yobB" /locus_tag="BSU_18820" /old_locus_tag="BSU18820" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 10376821; Product type h: extrachromosomal origin" /codon_start=1 /transl_table=11 /product="putative transcriptional regulator from bacteriophage; putative defective prophage 6" /protein_id="NP_389763.1" /db_xref="EnsemblGenomes-Gn:BSU18820" /db_xref="EnsemblGenomes-Tr:CAB13774" /db_xref="SubtiList:BG13496" /db_xref="UniProtKB/Swiss-Prot:O31836" /translation="MKIRKILLSSALSFGMLISAVPALAAGTSSEVAVKNEEYDYDTI YRISPLPMDFQPTIEYNGYTYTLTRHYFDYSIGFYTAIYTKVV*" gene 2050689..2050952 /gene="yobB" /locus_tag="BSU_18820" /old_locus_tag="BSU18820" downshifts 2050930 /Source="Nicolas_upshifts" /id="D1027" /incds=0 /nref=23 /ntot=100 /MaxReadThrough="0.60454" /MaxDrop="4.81085" /score="19.5390064" /energy="-8.7" /TU="NA" /idTUdmin="U1522" /TUdmin=3 /isTUend="TRUE" CDS complement(2051329..2053929) /gene="yppS" /locus_tag="BSU_18830" /old_locus_tag="BSU18830" /EC_number="2.7.9.-" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative PEP-dependent enzyme" /protein_id="NP_389764.1" /db_xref="EnsemblGenomes-Gn:BSU18830" /db_xref="EnsemblGenomes-Tr:CAB13775" /db_xref="GOA:O34309" /db_xref="InterPro:IPR002192" /db_xref="InterPro:IPR008279" /db_xref="InterPro:IPR013815" /db_xref="SubtiList:BG12657" /db_xref="UniProtKB/Swiss-Prot:O34309" /translation="MSSLVLGLHEIEKTQLSLVGGKGLHLGELSKIQGIQVPEGFCVT TVGYQKAIEQNETLQVLLDQLTMLKVEDRDQIGNISRKIRQIIMEVDIPSDVVKAVAQ YLSQFGEEHAYAVRSSATAEDLPHASFAGQQDTYLNITGVDAILQHISKCWASLFTDR AVIYRMQNGFDHSQVYLSVIVQRMVFPQASGILFTADPITSNRKVLSIDAGFGLGEAL VSGLVSADCFKVQDGQIIDKRIATKKMAIYGRKEGGTETQQIDSDQQKAQTLTDEQIL QLARIGRQIEAHFGQPQDIEWCLARDTFYIVQSRPITTLFPIPEASDQENHVYISVGH QQMMTDPIKPLGLSFFLLTTVAPMRKAGGRLFVDVTHHLASPDSREVFLKGMGQHDQL LKDALMTIIKRRDFIKSIPNDKTAPNPSRGNADMPAQVENDPTIVSDLIESSQTSIEE LKQNIQTKSGSDLFRFILEDIQELKKILFNPKSSVLIRTAMNASLWINEKMNEWLGEK NAADTLSQSVPHNITSEMGLALLDVADVIRPYPEVIDYLQHVKDDNFLDELAKFDGGS KTRDAIYDYLSKYGMRCTGEIDITRTRWSEKPTTLVPMILNNIKNFEPNVGHRKFEQG RQEALKKEQELLDRLKQLPDGEQKAKETKRAIDIIRNFSGFREYPKYGMVNRYFVYKQ ALLKEAEQLIEAGVIHEKEDIYYLTFEELHEVVRTHKLDYQIISTRKDEYTLYEKLSP PRVITSDGEIVTGEYKRENLPAGAIVGLPVSSGVIEGRARVILNMEDADLEDGDILVT SFTDPSWTPLFVSIKGLVTEVGGLMTHGAVIAREYGLPAVVGVENAAKLIKDGQRIRV HGTEGYIEIF*" gene complement(2051329..2053929) /gene="yppS" /locus_tag="BSU_18830" /old_locus_tag="BSU18830" S_feature complement(2053930..2054039) /Source="Nicolas_S_feature" /locus_tag="new_2053930_2054039_c" /HighExp="dia15, BC, S6, SMMPr, H2O2, S5, T-5.40H, S4, HPh, Sw" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S707" promotor_-35 2053955..2053962 /Source="Nicolas_upshift_promotors" /id="U1523" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.997002997002997" /psig=1 /xcortree=585 /SigmaFactorBS="ctcattctacatctccccttcaaaaaaaaaTATTGACAagag cttcctagcaGGATATAATAAAATTATAAGatggatatctataactttttaactagaa a" /listShort="S708" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2053977..2053996 /Source="Nicolas_upshift_promotors" /id="U1523" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.997002997002997" /psig=1 /xcortree=585 /SigmaFactorBS="ctcattctacatctccccttcaaaaaaaaaTATTGACAagag cttcctagcaGGATATAATAAAATTATAAGatggatatctataactttttaactagaa a" /listShort="S708" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 2053985..2054612 /Source="Nicolas_S_feature" /locus_tag="new_2053985_2054612" /HighExp="T5.0H, T4.0H, T3.30H, T3.0H, S1, T2.30H, Heat, S2, T-5.40H, C30" /AntisenseName="xynA" /AntisenseCor="-0.30871986344497798" /AntisenseRegPval="-6.6" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S708" upshifts 2053985 /Source="Nicolas_upshifts" /id="U1523" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.997002997002997" /psig=1 /xcortree=585 /SigmaFactorBS="ctcattctacatctccccttcaaaaaaaaaTATTGACAagag cttcctagcaGGATATAATAAAATTATAAGatggatatctataactttttaactagaa a" /listShort="S708" /GFF_Attribute="listLong" promotor_-10 complement(2054029..2054048) /Source="Nicolas_upshift_promotors" /id="U1524" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.41958041958042" /psig="0.999000999001" /xcortree=1451 /SigmaFactorBS="acctggtgaaatttcccaggttctttttatATTGCACaaaaa cagacacggTGATATAATCACACTACGTGcgctttctagttaaaaagttatagatatc c" /listShort="S707, pps" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2054039) /Source="Nicolas_upshifts" /id="U1524" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.41958041958042" /psig="0.999000999001" /xcortree=1451 /SigmaFactorBS="acctggtgaaatttcccaggttctttttatATTGCACaaaaa cagacacggTGATATAATCACACTACGTGcgctttctagttaaaaagttatagatatc c" /listShort="S707, pps" /GFF_Attribute="listLong" promotor_-35 complement(2054063..2054069) /Source="Nicolas_upshift_promotors" /id="U1524" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.41958041958042" /psig="0.999000999001" /xcortree=1451 /SigmaFactorBS="acctggtgaaatttcccaggttctttttatATTGCACaaaaa cagacacggTGATATAATCACACTACGTGcgctttctagttaaaaagttatagatatc c" /listShort="S707, pps" /GFF_Attribute="listLong" /label="promotor_-35" S_feature complement(2054085..2054544) /Source="Nicolas_S_feature" /locus_tag="new_2054085_2054544_c" /HighExp="S0, Lbstat, HiTm, dia0, ferm, Lbexp, T1.0H, M0t45, LBGtran, nit" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.995" /TUlongSig="SigA" /TUlongPSig="0.985" /label="S709" downshifts complement(2054127) /Source="Nicolas_upshifts" /id="D1028" /incds=0 /nref=87 /ntot=200 /MaxReadThrough="1.89557" /MaxDrop="5.26144" /score="1.97345986" /energy="-10.4" /TU="NA" /idTUdmin="U1525" /TUdmin=0 /isTUend="TRUE" downshifts complement(2054589) /Source="Nicolas_upshifts" /id="D1029" /incds=0 /nref=2 /ntot=26 /MaxReadThrough="5.28207" /MaxDrop="3.16026" /score="1.97345986" /energy="-10.4" /TU="U1525" /idTUdmin="U1525" /TUdmin="-462" /isTUend="FALSE" CDS complement(2054599..2055240) /gene="xynA" /locus_tag="BSU_18840" /old_locus_tag="BSU18840" /EC_number="3.2.1.8" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:7704256, 8628241, 16517552, 26559526" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7704256, 8628241, 16517552, 26559526; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="secreted endo-1,4-beta-xylanase" /protein_id="NP_389765.1" /db_xref="EnsemblGenomes-Gn:BSU18840" /db_xref="EnsemblGenomes-Tr:CAB13776" /db_xref="GOA:P18429" /db_xref="InterPro:IPR001137" /db_xref="InterPro:IPR013319" /db_xref="InterPro:IPR013320" /db_xref="InterPro:IPR018208" /db_xref="InterPro:IPR033119" /db_xref="InterPro:IPR033123" /db_xref="PDB:1AXK" /db_xref="PDB:1XXN" /db_xref="PDB:2B42" /db_xref="PDB:2B45" /db_xref="PDB:2B46" /db_xref="PDB:2DCY" /db_xref="PDB:2DCZ" /db_xref="PDB:2QZ3" /db_xref="PDB:2Z79" /db_xref="PDB:3EXU" /db_xref="PDB:3HD8" /db_xref="PDB:5K9Y" /db_xref="SubtiList:BG10808" /db_xref="UniProtKB/Swiss-Prot:P18429" /translation="MFKFKKNFLVGLSAALMSISLFSATASAASTDYWQNWTDGGGIV NAVNGSGGNYSVNWSNTGNFVVGKGWTTGSPFRTINYNAGVWAPNGNGYLTLYGWTRS PLIEYYVVDSWGTYRPTGTYKGTVKSDGGTYDIYTTTRYNAPSIDGDRTTFTQYWSVR QSKRPTGSNATITFSNHVNAWKSHGMNLGSNWAYQVMATEGYQSSGSSNVTVW*" gene complement(2054599..2055240) /gene="xynA" /locus_tag="BSU_18840" /old_locus_tag="BSU18840" S_feature complement(2055241..2055358) /Source="Nicolas_S_feature" /locus_tag="new_2055241_2055358_c" /HighExp="S0, HiTm, T1.0H, Gly, Lbstat, SMMPr, Lbtran, LBGstat, SMM, Lbexp" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.995" /TUlongSig="SigA" /TUlongPSig="0.985" /label="S710" promotor_-10 complement(2055335..2055354) /Source="Nicolas_upshift_promotors" /id="U1525" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.656343656343656" /psig="0.995004995004995" /xcortree=2292 /SigmaFactorBS="ttataatgtgtttctaggtatttgtaattgaattacaaatac ttttaaTATttgctcatgaattCGTGGTATTATACTGAAGGGgacgatcaaaagcttt g" /listShort="S710, xynA, S709" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2055358) /Source="Nicolas_upshifts" /id="U1525" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.656343656343656" /psig="0.995004995004995" /xcortree=2292 /SigmaFactorBS="ttataatgtgtttctaggtatttgtaattgaattacaaatac ttttaaTATttgctcatgaattCGTGGTATTATACTGAAGGGgacgatcaaaagcttt g" /listShort="S710, xynA, S709" /GFF_Attribute="listLong" promotor_-35 complement(2055368..2055370) /Source="Nicolas_upshift_promotors" /id="U1525" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.656343656343656" /psig="0.995004995004995" /xcortree=2292 /SigmaFactorBS="ttataatgtgtttctaggtatttgtaattgaattacaaatac ttttaaTATttgctcatgaattCGTGGTATTATACTGAAGGGgacgatcaaaagcttt g" /listShort="S710, xynA, S709" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2055868..2056107) /gene="yozV" /locus_tag="BSU_18849" /old_locus_tag="BSU18849" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type h : extrachromosomal origin" /codon_start=1 /transl_table=11 /product="putative phage protein; putative defective prophage 6" /protein_id="YP_003097736.1" /db_xref="EnsemblGenomes-Gn:BSU18849" /db_xref="EnsemblGenomes-Tr:CAX52631" /db_xref="GOA:C0H423" /db_xref="InterPro:IPR007829" /db_xref="UniProtKB/Swiss-Prot:C0H423" /translation="MVSKKNKIVAALLAFFFGGLGIHKFYLGRVGQGILYILFCWTGI PSIIAFIEFIIFLCGSEEGFDQKYNFYYFQQQSKA*" gene complement(2055868..2056107) /gene="yozV" /locus_tag="BSU_18849" /old_locus_tag="BSU18849" downshifts complement(2055888) /Source="Nicolas_upshifts" /id="D1030" /incds=0 /nref=31 /ntot=127 /MaxReadThrough="3.22282" /MaxDrop="3.97488" /score="-1.08247697" /energy="-4.5" /TU="U1526" /idTUdmin="U1526" /TUdmin="-529" /isTUend="FALSE" misc_feature complement(2056147..2056166) /Source="Nicolas_upshift_promotors" /id="U1526" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.57042957042957" /psig="0.985014985014985" /xcortree=2315 /SigmaFactorBS="taaaaaatctcaaaagaatttcaaaattttcacgatttctgg cggaaaATGCATTATAATGTGAAAGCattactttaaaaatggtagcaatgaactagga g" /listShort="yozV" /listLong="S710, xynA, S709" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(2056154) /Source="Nicolas_upshifts" /id="U1526" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.57042957042957" /psig="0.985014985014985" /xcortree=2315 /SigmaFactorBS="taaaaaatctcaaaagaatttcaaaattttcacgatttctgg cggaaaATGCATTATAATGTGAAAGCattactttaaaaatggtagcaatgaactagga g" /listShort="yozV" /listLong="S710, xynA, S709" promotor_-35 2056213..2056220 /Source="Nicolas_upshift_promotors" /id="U1527" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.897102897102897" /psig="0.99100899100899" /xcortree=3063 /SigmaFactorBS="gtgaaaattttgaaattcttttgagatttttTATTTTATtga gaaatgaaagcTCATATAATTGAACTAGATGgttttgggaggcatttattcaaaatgt a" /listShort="yobD, S711, yozI" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2056235..2056254 /Source="Nicolas_upshift_promotors" /id="U1527" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.897102897102897" /psig="0.99100899100899" /xcortree=3063 /SigmaFactorBS="gtgaaaattttgaaattcttttgagatttttTATTTTATtga gaaatgaaagcTCATATAATTGAACTAGATGgttttgggaggcatttattcaaaatgt a" /listShort="yobD, S711, yozI" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2056242 /Source="Nicolas_upshifts" /id="U1527" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.897102897102897" /psig="0.99100899100899" /xcortree=3063 /SigmaFactorBS="gtgaaaattttgaaattcttttgagatttttTATTTTATtga gaaatgaaagcTCATATAATTGAACTAGATGgttttgggaggcatttattcaaaatgt a" /listShort="yobD, S711, yozI" /GFF_Attribute="listLong" CDS 2056278..2056616 /gene="yobD" /locus_tag="BSU_18850" /old_locus_tag="BSU18850" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:10376821" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10376821; Product type h: extrachromosomal origin" /codon_start=1 /transl_table=11 /product="transcriptional regulator (phage-related, Xre family); putative defective prophage 6" /protein_id="NP_389766.1" /db_xref="EnsemblGenomes-Gn:BSU18850" /db_xref="EnsemblGenomes-Tr:CAB13777" /db_xref="GOA:O34647" /db_xref="InterPro:IPR001387" /db_xref="InterPro:IPR010982" /db_xref="InterPro:IPR027910" /db_xref="SubtiList:BG13497" /db_xref="UniProtKB/Swiss-Prot:O34647" /translation="MYCQRLRQLRKAHKLTMEQLAEKIGIAKSSYGGYEAESKKPPLD KLVILARLYDVSVDYILGLTDDPDPKVERKNLKEFLEKPDIHWDGYKLTPEILDPIRK ILKLVTANNN*" gene 2056278..2056616 /gene="yobD" /locus_tag="BSU_18850" /old_locus_tag="BSU18850" S_feature 2056617..2057213 /Source="Nicolas_S_feature" /locus_tag="new_2056617_2057213" /HighExp="M0t90, Lbstat, Lbtran, MG 150, M40t90, MG 15, SMM, GM 25, Fru, GM-0.1" /AntisenseName="yozH" /AntisenseCor="0.41013265801279702" /AntisenseRegPval="-11.6" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.991" /TUlongSig="NA" /TUlongPSig="NA" /label="S711" CDS complement(2056650..2057006) /gene="yozH" /locus_tag="BSU_18860" /old_locus_tag="BSU18860" /function="18: Unknown function" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein; putative defective prophage 6" /protein_id="NP_389767.2" /db_xref="EnsemblGenomes-Gn:BSU18860" /db_xref="EnsemblGenomes-Tr:CAB13778" /db_xref="SubtiList:BG13755" /db_xref="UniProtKB/Swiss-Prot:O31837" /translation="MNDLLFAAGNLHIGLGHDYLKCIALLINVKRFFSLTESYGNISD KLAVVAMKGVQFDQFEEAYKAYKETVAINQNSLVDFLSALITLIKAGEKLQKAGESLA IIMNKLLEMSPENSMK*" gene complement(2056650..2057006) /gene="yozH" /locus_tag="BSU_18860" /old_locus_tag="BSU18860" CDS 2057214..2057579 /gene="yozI" /locus_tag="BSU_18870" /old_locus_tag="BSU18870" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein; putative defective prophage 6" /protein_id="NP_389768.1" /db_xref="EnsemblGenomes-Gn:BSU18870" /db_xref="EnsemblGenomes-Tr:CAB13779" /db_xref="SubtiList:BG13756" /db_xref="UniProtKB/Swiss-Prot:O31838" /translation="MPKLYTCLICGYKGLIQNPLNNDGEYQKTFDICPCCDFEYGYSE DHDVSLGFIVTPDYLIDAAIQLYRKQWIENGMKTANPEDIPEELRNGDCLKFEVLLKQ LNSLNLDTENFEIKGFNGY*" gene 2057214..2057579 /gene="yozI" /locus_tag="BSU_18870" /old_locus_tag="BSU18870" S_feature complement(2057588..2058714) /Source="Nicolas_S_feature" /locus_tag="new_2057588_2058714_c" /HighExp="BC, Sw, HiOs, C90, Lbstat, M0t90, UNK1, M9-stat, HiTm, GM-0.1" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.997" /TUlongSig="SigA" /TUlongPSig="0.994" /label="S712" downshifts complement(2057631) /Source="Nicolas_upshifts" /id="D1031" /incds=0 /nref=3 /ntot=99 /MaxReadThrough="3.80479" /MaxDrop="4.2268" /score="22.3776508" /energy="-7.6" /TU="U1528" /idTUdmin="U1528" /TUdmin="-513" /isTUend="FALSE" CDS 2057801..2058460 /gene="yobE" /locus_tag="BSU_18880" /old_locus_tag="BSU18880" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type h : extrachromosomal origin" /codon_start=1 /transl_table=11 /product="putative SOS response associated phage protein; putative defective prophage 6" /protein_id="NP_389769.1" /db_xref="EnsemblGenomes-Gn:BSU18880" /db_xref="EnsemblGenomes-Tr:CAB13780" /db_xref="GOA:O34915" /db_xref="InterPro:IPR003738" /db_xref="InterPro:IPR036590" /db_xref="SubtiList:BG13498" /db_xref="UniProtKB/Swiss-Prot:O34915" /translation="MCGKFTLFSEFDDIIEQFNIDQFLPEGEYHPSYNVAPSQNILTI INDGSNNRLGKLRWGLIPPCAKDEKIGYKMINARAETLAEKPSFRKPLGSKRCIIPAD SFYEWKRLDPKTKIPMRIKLKSSNLFAFAGLYEKWNTLEGNLLYTCTIITIKPSELME DIHDRMPVILTDENKKEWLNPKNTDPDYLQSLLLPYDADDMEAYQVSSLVNSPELIES H*" gene 2057801..2058460 /gene="yobE" /locus_tag="BSU_18880" /old_locus_tag="BSU18880" downshifts 2058538 /Source="Nicolas_upshifts" /id="D1032" /incds=0 /nref=1 /ntot=20 /MaxReadThrough="1.22982" /MaxDrop="2.96245" /score="5.95470205" /energy="-19.6" /TU="NA" /idTUdmin="U1527" /TUdmin=990 /isTUend="FALSE" CDS complement(2058715..2059638) /gene="yobF" /locus_tag="BSU_18890" /old_locus_tag="BSU18890" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_389770.1" /db_xref="EnsemblGenomes-Gn:BSU18890" /db_xref="EnsemblGenomes-Tr:CAB13781" /db_xref="SubtiList:BG13499" /db_xref="UniProtKB/Swiss-Prot:O34780" /translation="MLVYIGNGHYCYSNSTAMFLSSIGENVSPQLVEILTGVGLGAMI EYEKNLYFSMRDPDDGINYALNILGFTAEEHQQASDLDDPFPLLKQQIKQNPVILGPL DMGELTYHPNHKNLNGSDHYVLGYQMDNENIYVQDPAGFPFVPLSLDQFKKAWMAERI PYRKGINKYWSTAKKVVTLDNNEIYERAIDYFKRTYRKFEKVDIGLIGREAICFYADQ LLNAPITADTIRHTTFFLFQLSARRANDYAMYFKDRHSHLSVLKTEQAKVFGICHSMS VNKDWKGISEKLMKLADLEDNFRLELLKVGY*" gene complement(2058715..2059638) /gene="yobF" /locus_tag="BSU_18890" /old_locus_tag="BSU18890" promotor_-10 complement(2059494..2059513) /Source="Nicolas_upshift_promotors" /id="U1528" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.746253746253746" /psig="0.997002997002997" /xcortree=3033 /SigmaFactorBS="tctcctcaacttgtagagatattaaCTGGTGTTgggttaggt gcCATGATAGAATATGAAAAAAacctttattttagtatgagagatcctgatgatggta t" /listShort="S712" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2059497) /Source="Nicolas_upshifts" /id="U1528" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.746253746253746" /psig="0.997002997002997" /xcortree=3033 /SigmaFactorBS="tctcctcaacttgtagagatattaaCTGGTGTTgggttaggt gcCATGATAGAATATGAAAAAAacctttattttagtatgagagatcctgatgatggta t" /listShort="S712" /GFF_Attribute="listLong" promotor_-35 complement(2059525..2059532) /Source="Nicolas_upshift_promotors" /id="U1528" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.746253746253746" /psig="0.997002997002997" /xcortree=3033 /SigmaFactorBS="tctcctcaacttgtagagatattaaCTGGTGTTgggttaggt gcCATGATAGAATATGAAAAAAacctttattttagtatgagagatcctgatgatggta t" /listShort="S712" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(2059649..2059668) /Source="Nicolas_upshift_promotors" /id="U1529" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.892107892107892" /psig="0.994005994005994" /xcortree=398 /SigmaFactorBS="aaatgatccagatgatgaatacgagaacggagcaatttaaTA TGGATTttcaattttcaaaaTTGTAAGGTTAACTTATCTAcccggaggtgatgttagt g" /listShort="yobF" /listLong="S712" /label="promotor_-10" upshifts complement(2059670) /Source="Nicolas_upshifts" /id="U1529" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.892107892107892" /psig="0.994005994005994" /xcortree=398 /SigmaFactorBS="aaatgatccagatgatgaatacgagaacggagcaatttaaTA TGGATTttcaattttcaaaaTTGTAAGGTTAACTTATCTAcccggaggtgatgttagt g" /listShort="yobF" /listLong="S712" promotor_-35 complement(2059683..2059690) /Source="Nicolas_upshift_promotors" /id="U1529" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.892107892107892" /psig="0.994005994005994" /xcortree=398 /SigmaFactorBS="aaatgatccagatgatgaatacgagaacggagcaatttaaTA TGGATTttcaattttcaaaaTTGTAAGGTTAACTTATCTAcccggaggtgatgttagt g" /listShort="yobF" /listLong="S712" /label="promotor_-35" CDS complement(2059691..2059864) /gene="yozW" /locus_tag="BSU_18898" /old_locus_tag="BSU18898" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein; putative defective prophage 6" /protein_id="YP_003097737.1" /db_xref="EnsemblGenomes-Gn:BSU18898" /db_xref="EnsemblGenomes-Tr:CAX52632" /db_xref="UniProtKB/Swiss-Prot:C0H424" /translation="MTEIKANSTVMIHVLADETLSSIKREYVEVDRKTEIGEKIIIVD KNDPDDEYENGAI*" gene complement(2059691..2059864) /gene="yozW" /locus_tag="BSU_18898" /old_locus_tag="BSU18898" CDS 2060009..2060233 /gene="yozX" /locus_tag="BSU_18899" /old_locus_tag="BSU18899" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type h : extrachromosomal origin" /codon_start=1 /transl_table=11 /product="putative phage protein; putative defective prophage 6" /protein_id="YP_003097738.1" /db_xref="EnsemblGenomes-Gn:BSU18899" /db_xref="EnsemblGenomes-Tr:CAX52633" /db_xref="UniProtKB/Swiss-Prot:C0H425" /translation="MNFLLDLFTNWTFDKVLDYTLAAVIWSVFKSRSKQNKYPGYFEK IRRYRNLHPLLRSLSMRVLLSITIHPYMFS*" gene 2060009..2060233 /gene="yozX" /locus_tag="BSU_18899" /old_locus_tag="BSU18899" CDS complement(2060237..2060692) /gene="yozJ" /locus_tag="BSU_18900" /old_locus_tag="BSU18900" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="NP_389771.1" /db_xref="EnsemblGenomes-Gn:BSU18900" /db_xref="EnsemblGenomes-Tr:CAB13782" /db_xref="SubtiList:BG13757" /db_xref="UniProtKB/Swiss-Prot:O31839" /translation="MADRYVLIEVNEDGEGRLKDEAVTWIDFRLSIVDFNASEGLNQL MEQISKDVKDELVLVLFNYRVKSSYDSWSGATEYEDFFDVEFFKVIKKNYKKFYQGLV TVELDVGINGFDNIESMPTDSNQNYYRNLIAEWEEFYNEDFIPLSLNKR*" gene complement(2060237..2060692) /gene="yozJ" /locus_tag="BSU_18900" /old_locus_tag="BSU18900" promotor_-35 2060752..2060759 /Source="Nicolas_upshift_promotors" /id="U1530" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.673326673326673" /psig="0.96003996003996" /xcortree=483 /SigmaFactorBS="aaatcacgattttaactatttatgatccattagtCACTTCCA aagcaacttccattTAACTCATAATTAATATATAaaatgtaaatggagttgatatatt t" /listShort="yozY" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2060774..2060793 /Source="Nicolas_upshift_promotors" /id="U1530" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.673326673326673" /psig="0.96003996003996" /xcortree=483 /SigmaFactorBS="aaatcacgattttaactatttatgatccattagtCACTTCCA aagcaacttccattTAACTCATAATTAATATATAaaatgtaaatggagttgatatatt t" /listShort="yozY" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2060778 /Source="Nicolas_upshifts" /id="U1530" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.673326673326673" /psig="0.96003996003996" /xcortree=483 /SigmaFactorBS="aaatcacgattttaactatttatgatccattagtCACTTCCA aagcaacttccattTAACTCATAATTAATATATAaaatgtaaatggagttgatatatt t" /listShort="yozY" /GFF_Attribute="listLong" CDS 2060817..2061077 /gene="yozY" /locus_tag="BSU_18908" /old_locus_tag="BSU18908" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type h : extrachromosomal origin" /codon_start=1 /transl_table=11 /product="putative transcriptional regulator from bacteriophage; putative defective prophage 6" /protein_id="YP_003097739.1" /db_xref="EnsemblGenomes-Gn:BSU18908" /db_xref="EnsemblGenomes-Tr:CAX52634" /db_xref="UniProtKB/Swiss-Prot:C0H426" /translation="MNLRKILLSSALSLGMLVSAAPVLATSSSSEVIVKSDEYDYDTI YQLSPLPNFKPSIEYNGYTYTLTRYYFDYSIQFYTAIYTKVV*" gene 2060817..2061077 /gene="yozY" /locus_tag="BSU_18908" /old_locus_tag="BSU18908" downshifts 2061024 /Source="Nicolas_upshifts" /id="D1033" /incds=0 /nref=1 /ntot=221 /MaxReadThrough="4.57606" /MaxDrop="3.58254" /score="4.613667" /energy="-8.7" /TU="U1530" /idTUdmin="U1530" /TUdmin="-638" /isTUend="FALSE" promotor_-35 2061492..2061495 /Source="Nicolas_upshift_promotors" /id="U1531" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.408591408591409" /psig="0.731268731268731" /xcortree=2853 /SigmaFactorBS="ataagagttattatatagggattacaCTACcattatctgggg gTGTATTAACATCCAAATACTcaaaagcaagaacaaatgtacccatagcacttccatt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2061509..2061528 /Source="Nicolas_upshift_promotors" /id="U1531" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.408591408591409" /psig="0.731268731268731" /xcortree=2853 /SigmaFactorBS="ataagagttattatatagggattacaCTACcattatctgggg gTGTATTAACATCCAAATACTcaaaagcaagaacaaatgtacccatagcacttccatt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2061526 /Source="Nicolas_upshifts" /id="U1531" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.408591408591409" /psig="0.731268731268731" /xcortree=2853 /SigmaFactorBS="ataagagttattatatagggattacaCTACcattatctgggg gTGTATTAACATCCAAATACTcaaaagcaagaacaaatgtacccatagcacttccatt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" downshifts 2061638 /Source="Nicolas_upshifts" /id="D1034" /incds=0 /nref=13 /ntot=69 /MaxReadThrough="3.18248" /MaxDrop="3.66335" /score="32.4789235" /energy="-13.7" /TU="U1530,U1531" /idTUdmin="U1530" /TUdmin="-24" /isTUend="FALSE" CDS 2061855..2061995 /gene="yozZ" /locus_tag="BSU_18909" /old_locus_tag="BSU18909" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type h : extrachromosomal origin" /pseudo /codon_start=1 /transl_table=11 /product="putative phage holin (fragment)" /db_xref="PSEUDO:CAX52635.1" /translation="MTVFGDDLTEKFNALLTFLTALGIIVDPTTQGISDSEQAMDYDS PR*" gene 2061855..2061995 /gene="yozZ" /locus_tag="BSU_18909" /old_locus_tag="BSU18909" /pseudo downshifts 2061992 /Source="Nicolas_upshifts" /id="D1035" /incds=0 /nref=1 /ntot=4 /MaxReadThrough="2.30104" /MaxDrop="4.04304" /score="32.4789235" /energy="-13.7" /TU="NA" /idTUdmin="U1531" /TUdmin=242 /isTUend="FALSE" promotor_-35 2062077..2062084 /Source="Nicolas_upshift_promotors" /id="U1532" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.99000999000999" /psig="0.999000999001" /xcortree=2950 /SigmaFactorBS="ttttttcaaatgaaaaaattgcagaaaactttacatccttTT ACAATTttttcaatgacTATGTTATGATTGTTTTCGAgagatttttgaaattttcaga a" /listShort="rapK, phrK" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2062096..2062115 /Source="Nicolas_upshift_promotors" /id="U1532" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.99000999000999" /psig="0.999000999001" /xcortree=2950 /SigmaFactorBS="ttttttcaaatgaaaaaattgcagaaaactttacatccttTT ACAATTttttcaatgacTATGTTATGATTGTTTTCGAgagatttttgaaattttcaga a" /listShort="rapK, phrK" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2062097 /Source="Nicolas_upshifts" /id="U1532" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.99000999000999" /psig="0.999000999001" /xcortree=2950 /SigmaFactorBS="ttttttcaaatgaaaaaattgcagaaaactttacatccttTT ACAATTttttcaatgacTATGTTATGATTGTTTTCGAgagatttttgaaattttcaga a" /listShort="rapK, phrK" /GFF_Attribute="listLong" CDS 2062150..2063265 /gene="rapK" /locus_tag="BSU_18910" /old_locus_tag="BSU18910" /EC_number="3.1.-.-" /function="16.3: Control" /function="16.12: Sense" /experiment="publication(s) with functional evidences, PMID:16816200, 25225273" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16816200, 25225273; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="response regulator aspartate phosphatase" /protein_id="NP_389772.1" /db_xref="EnsemblGenomes-Gn:BSU18910" /db_xref="EnsemblGenomes-Tr:CAB13783" /db_xref="GOA:O34930" /db_xref="InterPro:IPR011990" /db_xref="SubtiList:BG12664" /db_xref="UniProtKB/Swiss-Prot:O34930" /translation="MSKIASEVVATTLNDWYIAIKKQKVDESIKYYSEIKKLFDEMEE DQEVLAYYSLLEERHKMLLHSSRGEPLQKHTYFTEDNQNFITKTNDKLEYNFYLFEAM YEAYNKNYDRAINLYGLAEKKLAEIPDEIEAAEFYSKVSYLYTLVKQSIVAQHYIKNA ISIYKRHPDYKCKLATSTMIAAANYADMKRFEEAEQYYLEAIDIAKETKDEFLKAQLF HNLSIVYSDWNKPDKCIESLEKAIGNESWLHSIYYINSLFMMIKELFKIDEKMKAINF YNKAQERLILMENKVYEAKISILYNLYCGELKNNFNNCISNIEFLKQQNELESVDELS YIAAKRFESIGAFEEATSFFNAKIWAEQKMNQVEGIL*" gene 2062150..2063265 /gene="rapK" /locus_tag="BSU_18910" /old_locus_tag="BSU18910" promotor_-35 2062989..2062997 /Source="Nicolas_upshift_promotors" /id="U1533" /multdbtbs="SigH" /comp="M1" /sig="SigH" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=505 /SigmaFactorBS="aaattgacgaaaaaatgaaagccattaatttttacaataaag cACAGGAAAGactcatattaaTGGAGAATAAAGTATACGAagccaaaatcagcatcct g" /listShort="phrK" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 2063006 /Source="Nicolas_upshifts" /id="U1533" /multdbtbs="SigH" /comp="M1" /sig="SigH" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=505 /SigmaFactorBS="aaattgacgaaaaaatgaaagccattaatttttacaataaag cACAGGAAAGactcatattaaTGGAGAATAAAGTATACGAagccaaaatcagcatcct g" /listShort="phrK" /GFF_Attribute="listLong" promotor_-10 2063009..2063027 /Source="Nicolas_upshift_promotors" /id="U1533" /multdbtbs="SigH" /comp="M1" /sig="SigH" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=505 /SigmaFactorBS="aaattgacgaaaaaatgaaagccattaatttttacaataaag cACAGGAAAGactcatattaaTGGAGAATAAAGTATACGAagccaaaatcagcatcct g" /listShort="phrK" /GFF_Attribute="listLong" /label="promotor_-10" CDS 2063262..2063384 /gene="phrK" /locus_tag="BSU_18920" /old_locus_tag="BSU18920" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:11587781, 16816200" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11587781, 16816200; Product type r: regulator" /codon_start=1 /transl_table=11 /product="secreted regulator of the activity of phosphatase RapK" /protein_id="NP_389773.1" /db_xref="EnsemblGenomes-Gn:BSU18920" /db_xref="EnsemblGenomes-Tr:CAB13784" /db_xref="InterPro:IPR030968" /db_xref="SubtiList:BG12646" /db_xref="UniProtKB/Swiss-Prot:O31840" /translation="MKKLVLCVSILAVILSGVALTQLSTDSPSNIQVAERPVGG*" gene 2063262..2063384 /gene="phrK" /locus_tag="BSU_18920" /old_locus_tag="BSU18920" downshifts 2063378 /Source="Nicolas_upshifts" /id="D1036" /incds=0 /nref=232 /ntot=252 /MaxReadThrough="2.33184" /MaxDrop="6.45227" /score="9.89565332" /energy="-10.4" /TU="NA" /idTUdmin="U1532" /TUdmin=0 /isTUend="TRUE" CDS complement(2063510..2064163) /gene="yobHc" /locus_tag="BSU_18930" /old_locus_tag="BSU18930" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /pseudo /codon_start=1 /transl_table=11 /product="fragment of putative DNA phage repair protein; putative defective prophage 6" /db_xref="EnsemblGenomes-Gn:BSU18930" /db_xref="EnsemblGenomes-Tr:CAB13785" /db_xref="GOA:C0SPA8" /db_xref="InterPro:IPR001126" /db_xref="InterPro:IPR017961" /db_xref="InterPro:IPR024728" /db_xref="InterPro:IPR036775" /db_xref="PSEUDO:CAB13785.2" /db_xref="SubtiList:BG13500" /db_xref="UniProtKB/Swiss-Prot:C0SPA8" /translation="MAKAIQSSMWREFGLMCTVGIGDNMLLSKLALDLESKKTKSGIA RWRYEDVPNRLWKVRPLSKMWGIGGRMERNLNRMGISTVGQLAKFPLELLEKKFGIMG NQLYYHAHGIDLSEIGAPLMQGQISFGKSQILFRDYTKREEIKAVLLEICEEVARRAR TYNKVGRTISLGIGYSKDELGGGFHRSKTIDFPTNITMDIYKCCLMFFNKFYSGKKQ* " gene complement(2063510..2064163) /gene="yobHc" /locus_tag="BSU_18930" /old_locus_tag="BSU18930" /pseudo downshifts complement(2063784) /Source="Nicolas_upshifts" /id="D1037" /incds=1 /nref=1 /ntot=2 /MaxReadThrough="1.36944" /MaxDrop="2.50062" /score="17.2005818" /energy="-10" /TU="NA" /idTUdmin="U1535" /TUdmin=1628 /isTUend="FALSE" CDS complement(2064200..2064547) /gene="yobHm" /locus_tag="BSU_18940" /old_locus_tag="BSU18940" /function="16.9: Replicate" /function="16.5: Explore" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 12137951; Product type h: extrachromosomal origin" /pseudo /codon_start=1 /transl_table=11 /product="putative phage DNA repair protein fragment; putative defective prophage 6" /db_xref="EnsemblGenomes-Gn:BSU18940" /db_xref="EnsemblGenomes-Tr:CAB13786" /db_xref="GOA:O31841" /db_xref="InterPro:IPR001126" /db_xref="PSEUDO:CAB13786.1" /db_xref="SubtiList:BG13758" /db_xref="UniProtKB/Swiss-Prot:O31841" /translation="MTDYSQFPRENILCVDMKSFYASVSAVAMGLNPLTCYLAVVGNT DRQGSVVLAASPALKKDFGIKTGSRLFEIPEDPRIYIVNPQMKLFIRVSTEITKLFYR FVPEKCVHTYSID*" gene complement(2064200..2064547) /gene="yobHm" /locus_tag="BSU_18940" /old_locus_tag="BSU18940" /pseudo CDS complement(2064540..2064833) /gene="yozL" /locus_tag="BSU_18950" /old_locus_tag="BSU18950" /function="16.6: Maintain" /function="16.8: Protect" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 12137951" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein of phage origin; putative defective prophage 6" /protein_id="NP_389776.1" /db_xref="EnsemblGenomes-Gn:BSU18950" /db_xref="EnsemblGenomes-Tr:CAB13787" /db_xref="InterPro:IPR014962" /db_xref="SubtiList:BG13759" /db_xref="UniProtKB/Swiss-Prot:O31842" /translation="MMLEQLIQLKQDLIDGSKVEKPSLDDKQIDEMDILVSEALEFNK ELKFKLFNKGFVENVTGRVHYINFEQQKLHVKDQNDNTVYINMNNIIRVIYND*" gene complement(2064540..2064833) /gene="yozL" /locus_tag="BSU_18950" /old_locus_tag="BSU18950" upshifts 2064984 /Source="Nicolas_upshifts" /id="U1534" /multdbtbs="-" /comp="M1" /sig="SigA" /pcomp="0.340659340659341" /psig="0.65034965034965" /xcortree=472 /SigmaFactorBS="tatagatcagaacaaaagttcgatgtaaatgttggtaataaa atataaaggtcaataatgaTATCCGTAGTATTAATAAAGgagagattcttttcgacga g" /listShort="yozM" /GFF_Attribute="listLong" misc_feature 2064985..2065004 /Source="Nicolas_upshift_promotors" /id="U1534" /multdbtbs="-" /comp="M1" /sig="SigA" /pcomp="0.340659340659341" /psig="0.65034965034965" /xcortree=472 /SigmaFactorBS="tatagatcagaacaaaagttcgatgtaaatgttggtaataaa atataaaggtcaataatgaTATCCGTAGTATTAATAAAGgagagattcttttcgacga g" /listShort="yozM" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" CDS 2065042..2065377 /gene="yozM" /locus_tag="BSU_18960" /old_locus_tag="BSU18960" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type h : extrachromosomal origin" /codon_start=1 /transl_table=11 /product="putative bacteriophage protein; putative defective prophage 6" /protein_id="NP_389777.1" /db_xref="EnsemblGenomes-Gn:BSU18960" /db_xref="EnsemblGenomes-Tr:CAB13788" /db_xref="SubtiList:BG13760" /db_xref="UniProtKB/Swiss-Prot:O31843" /translation="MKKRLIGFLVLVPALIMWGITLIESNKKTPVEVLESAWDEFGLF SFEIGITDPAITIGMDQTKSEAKLREYLKDNLSREAKEKYKIYIFKDDTDKLEKEHQE YLKENNLNK*" gene 2065042..2065377 /gene="yozM" /locus_tag="BSU_18960" /old_locus_tag="BSU18960" promotor_no_box complement(2065416..2065516) /Source="Nicolas_upshift_promotors" /id="U1535" /multdbtbs="-" /comp="M21" /sig="Sig-" /pcomp="0.68031968031968" /psig="0.040959040959041" /xcortree=286 /SigmaFactorBS="aaagcgttggtgactgcattagagtctaaaaactacatatcc tcttttaaagaagatagagagagattacgtgtgaatactaaaaaaaaataaagaataa c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_no_box" downshifts complement(2065423) /Source="Nicolas_upshifts" /id="D1038" /incds=0 /nref=148 /ntot=238 /MaxReadThrough="2.4012" /MaxDrop="4.9328" /score="17.2005818" /energy="-10" /TU="NA" /idTUdmin="U1535" /TUdmin="-11" /isTUend="TRUE" CDS complement(2065424..2069029) /gene="yobI" /locus_tag="BSU_18970" /old_locus_tag="BSU18970" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15128444; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative phage repair NTPase with transmembrane helices; putative defective prophage 6" /protein_id="NP_389778.1" /db_xref="EnsemblGenomes-Gn:BSU18970" /db_xref="EnsemblGenomes-Tr:CAB13789" /db_xref="GOA:O34784" /db_xref="InterPro:IPR011646" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG13501" /db_xref="UniProtKB/Swiss-Prot:O34784" /translation="MGEIKKKFVQWLEKLLIRLKEPNVKEESLFEDLSPSNDVDTDGK YSKALSWGLENKKVKNIALTGPYGSGKSSILNTFQKQYSREYSFLNISLATFNTDTDD MENKLEKSILQQMIYRVHDRTIPFSRFKRIKHIRTKSIIINLIFFFAFIIVGIYLFKP DALKGIYAETLVSRSLGTEDQQQIRLTILLALFFIVYPLLAYKRIYHFVRANLKLNKV TIANTTLEKNTGEENSSIFDKYLDEILYFFEASKYNVVIFEDLDRFNNIGIFERLREL NELINNSEQIDRRVVFIYAIKDDIFGDADTEKLTRDRTKFFDFIIPVIPIINASNSGD ILKKKIKHSPYSDLINTHFLEDVTIYIDDMRVLKNIFNEFVIYQQKLSAIDLDPNKML AMIIYKNIYPVDFSKLQYNKGLVYEIFQKKQLIIEEQIKLINAKIQQLERKLANIEVE SLKSIAELNFIYLSELEISNLNSNYDINIDGEVFRGNTSNKDRFFEKLKNADTIYCYL RNRNGPATIKEIATVFGRKPNYFEREDAIKAIEKNEIQKFKKELLELEREKQEIRAQS LQVLITKMNSKDVFSDKLYEKKLLVYLLRHGYIDEMYNHYITYFYPESLSLSDIKFVF SIKNHESLPYSFELDNIGKIMSKLVGAEFKQIEVLNFHLLNYIMDHSEYRNYYDSIIE RLANGSKESVTFIDGFKERAINKAAFIQSISSKWDDFWSFIELRSNYTQQKKEEYLSD ILTYADIADIIRMNKESVMSFTLSKYLNLLSLVSDEEKIKELLLKLQVKFKSLDHLLN SETIYDFVVQRNLYEINIKTLSVILNDAPNITYAAVKNSDQQAVINYVNDNIDIFVEK VLLTEEIEEPEESFLELLNREDLDKRVKHAMIMKKTFAISDIGELIKELWPIVIRENK MVACWSNVITSYVEYNKKMPDFLIAFLNNPVNRKELSKNNIEAFDDKFDEAILEDISE EIINSRDITDETFEVLIASIQSWIYFPLGNVSEKRAKLLIDNDLLSLTPENFKELKLN FDTLHIQLALRNPDEFIDKQGDFSLDANDIKQLIDSNELSQFNKEIFVQHLNSNCLTD GNNDILKDTIYFINEHNLKITNELLTFLLESPTTLDTRLSLLAGQIKHIDNESITEFL TKIGEPYSEIAEKGRRIKISNNRTNKALVTALESKNYISSFKEDRERLRVNTKKK*" gene complement(2065424..2069029) /gene="yobI" /locus_tag="BSU_18970" /old_locus_tag="BSU18970" upshifts complement(2065456) /Source="Nicolas_upshifts" /id="U1535" /multdbtbs="-" /comp="M21" /sig="Sig-" /pcomp="0.68031968031968" /psig="0.040959040959041" /xcortree=286 /SigmaFactorBS="aaagcgttggtgactgcattagagtctaaaaactacatatcc tcttttaaagaagatagagagagattacgtgtgaatactaaaaaaaaataaagaataa c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" S_feature complement(2069030..2069174) /Source="Nicolas_S_feature" /locus_tag="new_2069030_2069174_c" /HighExp="LBGstat, Lbstat, M0t90, T3.0H, T1.30H, T3.30H, MG 150, T2.30H, T4.0H, T1.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigD" /TUshortPSig="1, 0.936" /TUlongSig="SigWXY" /TUlongPSig=1 /label="S713" misc_feature complement(2069167..2069186) /Source="Nicolas_upshift_promotors" /id="U1536" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.998001998001998" /psig=1 /xcortree=3220 /SigmaFactorBS="tgtgttgtttattgatcatctttttttcagaaacttttaatg ccctttCATGTTACAATTAATAGTGAatttcaactggcgataaaggactatattagat g" /listShort="S713, yobI" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(2069174) /Source="Nicolas_upshifts" /id="U1536" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.998001998001998" /psig=1 /xcortree=3220 /SigmaFactorBS="tgtgttgtttattgatcatctttttttcagaaacttttaatg ccctttCATGTTACAATTAATAGTGAatttcaactggcgataaaggactatattagat g" /listShort="S713, yobI" /GFF_Attribute="listLong" S_feature complement(2069176..2069261) /Source="Nicolas_S_feature" /locus_tag="new_2069176_2069261_c" /HighExp="LBGstat, C30, Lbstat, M0t90, GM 120, GM 25, GM 150, nit, GM 90, MG 150" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigD, SigWXY" /TUshortPSig="0.936, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S714" CDS complement(2069262..2069561) /gene="yoyA" /locus_tag="BSU_18979" /old_locus_tag="BSU18979" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function; Product type h : extrachromosomal origin" /pseudo /codon_start=1 /transl_table=11 /product="putative fragment of phage protein; putative defective prophage 6" /db_xref="PSEUDO:CAX52636.1" /translation="MATEGYGGNNSAPSRSIGFSEFCETLEKNEVVKPENKKSSLDLN NSLDYWKSRFNPGGNLSALDSQVLDIIKKAYNLGMVNKDNMLLRNEAINAYKNSI*" gene complement(2069262..2069561) /gene="yoyA" /locus_tag="BSU_18979" /old_locus_tag="BSU18979" /pseudo S_feature complement(2069562..2069699) /Source="Nicolas_S_feature" /locus_tag="new_2069562_2069699_c" /HighExp="LBGstat, C30, MG 150, GM 150, M0t90, Lbstat, GM 25, GM 90, GM 120, T1.30H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigD, SigWXY" /TUshortPSig="0.936, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S715" promotor_-10 complement(2069677..2069695) /Source="Nicolas_upshift_promotors" /id="U1537" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp="0.936063936063936" /psig="0.936063936063936" /xcortree=3232 /SigmaFactorBS="gtgaaaggaacttgcaaaatgcaggttcttttttgtattcaa ttATTAAATcatttgaatgattGTCGATATTTAATATGTGTaaaaatggaaaaggtgc t" /listShort="S715, yoyA, S714, S713, yobI" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2069699) /Source="Nicolas_upshifts" /id="U1537" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp="0.936063936063936" /psig="0.936063936063936" /xcortree=3232 /SigmaFactorBS="gtgaaaggaacttgcaaaatgcaggttcttttttgtattcaa ttATTAAATcatttgaatgattGTCGATATTTAATATGTGTaaaaatggaaaaggtgc t" /listShort="S715, yoyA, S714, S713, yobI" /GFF_Attribute="listLong" promotor_-35 complement(2069709..2069715) /Source="Nicolas_upshift_promotors" /id="U1537" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp="0.936063936063936" /psig="0.936063936063936" /xcortree=3232 /SigmaFactorBS="gtgaaaggaacttgcaaaatgcaggttcttttttgtattcaa ttATTAAATcatttgaatgattGTCGATATTTAATATGTGTaaaaatggaaaaggtgc t" /listShort="S715, yoyA, S714, S713, yobI" /GFF_Attribute="listLong" /label="promotor_-35" misc_RNA complement(2069732..2070115) /gene="asrE" /locus_tag="BSU_misc_RNA_74" /product="small regulatory antitoxin RNA, toxin-antitoxin type I system (BsrE/AsrE)" /experiment="publication(s) with functional evidences, PMID:18948176, 23059907, 24576839, 26565032, 26940229" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 18948176, 23059907, 24576839, 26565032, 26940229; Product type n: RNA" gene complement(2069732..2070115) /gene="asrE" /locus_tag="BSU_misc_RNA_74" S_feature complement(2069746..2069982) /Source="Nicolas_S_feature" /locus_tag="new_2069746_2069982_c" /HighExp="Salt, Etha, S4, LoTm, dia5, Diami, S5, MG 120, S3, aero" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigWXY" /TUshortPSig="0.518, 1" /TUlongSig="SigA" /TUlongPSig=1 /label="S716" promotor_-35 2069779..2069781 /Source="Nicolas_upshift_promotors" /id="U1538" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.774225774225774" /psig=1 /xcortree=474 /SigmaFactorBS="tttgcaagttcctttcacgttgtcaatatattgtgaaTTTtt aacgacaagggcaTTTATGTATAGTATGATATTtcctgtacagtaagttttgctcact c" /listShort="S717" /GFF_Attribute="listLong" /label="promotor_-35" downshifts complement(2069789) /Source="Nicolas_upshifts" /id="D1039" /incds=0 /nref=39 /ntot=216 /MaxReadThrough="3.37292" /MaxDrop="5.0558" /score="17.2005818" /energy="-10" /TU="U1541" /idTUdmin="U1539" /TUdmin=1 /isTUend="TRUE" promotor_-10 2069797..2069816 /Source="Nicolas_upshift_promotors" /id="U1538" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.774225774225774" /psig=1 /xcortree=474 /SigmaFactorBS="tttgcaagttcctttcacgttgtcaatatattgtgaaTTTtt aacgacaagggcaTTTATGTATAGTATGATATTtcctgtacagtaagttttgctcact c" /listShort="S717" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2069802 /Source="Nicolas_upshifts" /id="U1538" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.774225774225774" /psig=1 /xcortree=474 /SigmaFactorBS="tttgcaagttcctttcacgttgtcaatatattgtgaaTTTtt aacgacaagggcaTTTATGTATAGTATGATATTtcctgtacagtaagttttgctcact c" /listShort="S717" /GFF_Attribute="listLong" S_feature 2069824..2069977 /Source="Nicolas_S_feature" /locus_tag="new_2069824_2069977" /HighExp="T1.30H, B60, T2.0H, M9-stat, BT, T0.30H, B36, T1.0H, T3.0H, BC" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.87861900000000004" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S717" CDS 2069883..2069975 /gene="bsrE" /locus_tag="BSU_18978" /old_locus_tag="BSU18978" /experiment="publication(s) with functional evidences, PMID:26565032, 26940229" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 26565032, 26940229; Product type f: factor" /codon_start=1 /transl_table=11 /product="type I toxin (BsrE/AsrE)" /protein_id="YP_009513965.1" /translation="MSTFQALMLMLAIGSFIIALLTYIEKIDLP*" gene 2069883..2069975 /gene="bsrE" /locus_tag="BSU_18978" /old_locus_tag="BSU18978" downshifts 2069934 /Source="Nicolas_upshifts" /id="D1040" /incds=0 /nref=1 /ntot=6 /MaxReadThrough="6.71009" /MaxDrop="3.13767" /score="33.1812693" /energy="-14.4" /TU="U1538" /idTUdmin="U1538" /TUdmin="-66" /isTUend="FALSE" S_feature complement(2069984..2070118) /Source="Nicolas_S_feature" /locus_tag="new_2069984_2070118_c" /HighExp="T-0.40H, T0.0H, T0.30H, Salt, S4, M9-stat, T-1.10H, S7, B60, S5" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigWXY" /TUshortPSig="0.518, 1" /TUlongSig="SigA" /TUlongPSig=1 /label="S718" downshifts 2070000 /Source="Nicolas_upshifts" /id="D1041" /incds=0 /nref=135 /ntot=196 /MaxReadThrough="2.41468" /MaxDrop="5.72925" /score="33.1812693" /energy="-14.4" /TU="NA" /idTUdmin="U1538" /TUdmin=0 /isTUend="TRUE" downshifts complement(2070027) /Source="Nicolas_upshifts" /id="D1042" /incds=0 /nref=13 /ntot=114 /MaxReadThrough="6.34283" /MaxDrop="4.1536" /score="3.24083135" /energy="-14.3" /TU="U1539,U1541" /idTUdmin="U1539" /TUdmin="-237" /isTUend="FALSE" upshifts complement(2070118) /Source="Nicolas_upshifts" /id="U1539" /multdbtbs="-" /comp="M3" /sig="SigA" /pcomp="0.44955044955045" /psig="0.518481518481518" /xcortree=755 /SigmaFactorBS="cttgaggtttattgtaatgcatttcacggaaaatgtgttata atcagtttTAcaatacattacagtgcatttctttaatgagaaatgcataaaataaaaa a" /listShort="S718, S716" /GFF_Attribute="listLong" S_feature complement(2070120..2070243) /Source="Nicolas_S_feature" /locus_tag="new_2070120_2070243_c" /HighExp="T-0.40H, T0.0H, T0.30H, Salt, T-1.10H, T1.0H, T-1.40H, Etha, SMMPr, T1.30H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigWXY" /TUshortPSig=1 /TUlongSig="SigA" /TUlongPSig=1 /label="S719" misc_feature complement(2070127..2070128) /Source="Nicolas_upshift_promotors" /id="U1539" /multdbtbs="-" /comp="M3" /sig="SigA" /pcomp="0.44955044955045" /psig="0.518481518481518" /xcortree=755 /SigmaFactorBS="cttgaggtttattgtaatgcatttcacggaaaatgtgttata atcagtttTAcaatacattacagtgcatttctttaatgagaaatgcataaaataaaaa a" /listShort="S718, S716" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" CDS complement(2070244..2071086) /gene="yobJ" /locus_tag="BSU_18980" /old_locus_tag="BSU18980" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 11866510" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function; putative defective prophage 6" /protein_id="NP_389779.1" /db_xref="EnsemblGenomes-Gn:BSU18980" /db_xref="EnsemblGenomes-Tr:CAB13790" /db_xref="GOA:O34774" /db_xref="SubtiList:BG13502" /db_xref="UniProtKB/Swiss-Prot:O34774" /translation="MELLDIWNWIQQNGILTAVITGIVALLFNQRQKSIERFYSQSGE TLEKILEPMYYSLKEIKNEEDENHKMVLIEKFFEEYSGKKGKLSKLRNILLIDQILNT EDCFREYILNKNSENRKKLFYKMRMLDQAVNKEYRSIFVTLNKNYNWYKVLFRTNYIL SAVFVFVRWFKETLAFFVGASAFAFIPLLYDKYLGEQVLGNWLEVNKLIFGLSCSALY IFWIIHYFLLKDTMQRKDEISLFQEWFDKTKLGKWTNKNVWGKIGNWNVERRARRVRN DEDV*" gene complement(2070244..2071086) /gene="yobJ" /locus_tag="BSU_18980" /old_locus_tag="BSU18980" promotor_-35 2070581..2070584 /Source="Nicolas_upshift_promotors" /id="U1540" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.978021978021978" /psig="0.011988011988012" /xcortree=47 /SigmaFactorBS="aagcaaatgctgaagcaccgacaaaaaaagctagagtttctt taaacCATCtaacaaaaacaaaaaCAGCGcttaaaatataattcgttctaaaaagaac t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 2070594 /Source="Nicolas_upshifts" /id="U1540" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.978021978021978" /psig="0.011988011988012" /xcortree=47 /SigmaFactorBS="aagcaaatgctgaagcaccgacaaaaaaagctagagtttctt taaacCATCtaacaaaaacaaaaaCAGCGcttaaaatataattcgttctaaaaagaac t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 2070600..2070604 /Source="Nicolas_upshift_promotors" /id="U1540" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.978021978021978" /psig="0.011988011988012" /xcortree=47 /SigmaFactorBS="aagcaaatgctgaagcaccgacaaaaaaagctagagtttctt taaacCATCtaacaaaaacaaaaaCAGCGcttaaaatataattcgttctaaaaagaac t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-10 complement(2071112..2071127) /Source="Nicolas_upshift_promotors" /id="U1541" /multdbtbs="SigW" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1677 /SigmaFactorBS="agaagttttctagtcccgttttataTGAAACCTTTtttattt tagcCCGTATTAAAAGTAAAttcagagagaaggggagaagcttaattggagttattag a" /listShort="yobJ, S719, S718, S716, S715, yoyA, S714" /listLong="S713, yobI" /label="promotor_-10" upshifts complement(2071113) /Source="Nicolas_upshifts" /id="U1541" /multdbtbs="SigW" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1677 /SigmaFactorBS="agaagttttctagtcccgttttataTGAAACCTTTtttattt tagcCCGTATTAAAAGTAAAttcagagagaaggggagaagcttaattggagttattag a" /listShort="yobJ, S719, S718, S716, S715, yoyA, S714" /listLong="S713, yobI" S_feature complement(2071115..2071197) /Source="Nicolas_S_feature" /locus_tag="new_2071115_2071197_c" /HighExp="MG 150, T-3.40H, Cold, SMM, Lbstat, SMMPr, ferm, T-2.40H, Fru, LBGstat" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S720" promotor_-35 complement(2071139..2071148) /Source="Nicolas_upshift_promotors" /id="U1541" /multdbtbs="SigW" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1677 /SigmaFactorBS="agaagttttctagtcccgttttataTGAAACCTTTtttattt tagcCCGTATTAAAAGTAAAttcagagagaaggggagaagcttaattggagttattag a" /listShort="yobJ, S719, S718, S716, S715, yoyA, S714" /listLong="S713, yobI" /label="promotor_-35" S_feature complement(2071199..2071285) /Source="Nicolas_S_feature" /locus_tag="new_2071199_2071285_c" /HighExp="Lbstat, M0t90, HiOs, HiTm, M40t90, dia15, S2, S1, T-0.40H, G/S" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S721" downshifts complement(2071242) /Source="Nicolas_upshifts" /id="D1043" /incds=0 /nref=5 /ntot=191 /MaxReadThrough="4.07519" /MaxDrop="4.09712" /score="-3.79237769" /energy="-8.4" /TU="U1542" /idTUdmin="U1542" /TUdmin="-110" /isTUend="FALSE" CDS complement(2071286..2071744) /gene="rttM" /locus_tag="BSU_18990" /old_locus_tag="BSU18990" /function="17.2: Prophage functions" /experiment="publication(s) with functional evidences, PMID:22200572" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 22200572; Product type f: factor" /codon_start=1 /transl_table=11 /product="antitoxin inhibiting Rnase RttL" /protein_id="NP_389780.1" /db_xref="EnsemblGenomes-Gn:BSU18990" /db_xref="EnsemblGenomes-Tr:CAB13791" /db_xref="InterPro:IPR018958" /db_xref="PDB:2PRV" /db_xref="SubtiList:BG13503" /db_xref="UniProtKB/Swiss-Prot:O34596" /translation="MIYSKVENFINENKQNAIFTEGASHENIGRIEENLQCDLPNSYK WFLEKYGAGGLFGVLVLGYNFDHASVVNRTNEYKEHYGLTDGLVVIEDVDYFAYCLDT NKMKDGECPVVEWDRVIGYQDTVADSFIEFFYNKIQEAKDDWDEDEDWDD*" gene complement(2071286..2071744) /gene="rttM" /locus_tag="BSU_18990" /old_locus_tag="BSU18990" CDS complement(2071754..2073556) /gene="rttL" /locus_tag="BSU_19000" /old_locus_tag="BSU19000" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:22200572" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 22200572; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="phage toxin ribonuclease; putative defective prophage 6" /protein_id="NP_389781.1" /db_xref="EnsemblGenomes-Gn:BSU19000" /db_xref="EnsemblGenomes-Tr:CAB13792" /db_xref="GOA:O34330" /db_xref="InterPro:IPR006829" /db_xref="InterPro:IPR026834" /db_xref="SubtiList:BG13504" /db_xref="UniProtKB/Swiss-Prot:O34330" /translation="MKVFEADSLLFEADKRTKEYKELRSQMVKLKKAFKEVANLDDSE FSGKGADNIKAFYHGHVGVTDQWIDLIDMKIAFLSSMSATLEDAKMSDAYIEESFLEH ELANAYAKSKSIMSEQKKAMKDILNNINDILPLEIFSTEDFKDKLSSADDKREKTIDK LNKLDEDLKTEYAETEPNEQFIQQDFKKLQESTGKGKNATPIHYNAKAYRESDIHKKK GDIEKHSEAYLSVKKEEAKEREIKELKKKLNDGVSDPDEYLEIAKKVGYENLEPTQVQ LAVQIEQAKQLEGAGEITWDIVKGVGVGLYDVGKDTVTGIWDFITDPGETLSALGNAA MHPVKTYDAISAAIEESYQKDMVNGDAYSRSRWVTYAIGSVAVAVVGTKGAGAINKAD AAGKVINKASQAGKKIKDVKIPDLLPYNPKYKLALADNVPYNVVDSQNLKNELLTNAK KIPDGTRKPFTGQKKSPPWLNKEKYDAYEIEGKVKAKGKVKDVSRRVYTMKDIDINQK TEFGVTNLQLMKNGNAPYAKDGTQINLHHLIQEEPGPMLEIPNSLHTKYSDVIHQLKS DGESFRNDKVLKAQYESFRKRYWKWRAKQFENEN*" gene complement(2071754..2073556) /gene="rttL" /locus_tag="BSU_19000" /old_locus_tag="BSU19000" promotor_-10 complement(2073580..2073599) /Source="Nicolas_upshift_promotors" /id="U1542" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.987012987012987" /psig=1 /xcortree=3217 /SigmaFactorBS="gtgtgatgtataagacagtcattttggctgtctttttcTGTT ATTCaattagattacTGTGGTAAAATTTACATAGAagtagtctaggaaggagaatgat a" /listShort="yobL, yobK, S721, S720" /listLong="yobJ, S719, S718, S716" /label="promotor_-10" upshifts complement(2073596) /Source="Nicolas_upshifts" /id="U1542" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.987012987012987" /psig=1 /xcortree=3217 /SigmaFactorBS="gtgtgatgtataagacagtcattttggctgtctttttcTGTT ATTCaattagattacTGTGGTAAAATTTACATAGAagtagtctaggaaggagaatgat a" /listShort="yobL, yobK, S721, S720" /listLong="yobJ, S719, S718, S716" promotor_-35 complement(2073611..2073618) /Source="Nicolas_upshift_promotors" /id="U1542" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.987012987012987" /psig=1 /xcortree=3217 /SigmaFactorBS="gtgtgatgtataagacagtcattttggctgtctttttcTGTT ATTCaattagattacTGTGGTAAAATTTACATAGAagtagtctaggaaggagaatgat a" /listShort="yobL, yobK, S721, S720" /listLong="yobJ, S719, S718, S716" /label="promotor_-35" CDS complement(2073658..2074215) /gene="yobM" /locus_tag="BSU_19010" /old_locus_tag="BSU19010" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type h : extrachromosomal origin" /codon_start=1 /transl_table=11 /product="putative phage protein; putative defective prophage 6" /protein_id="NP_389782.3" /db_xref="EnsemblGenomes-Gn:BSU19010" /db_xref="EnsemblGenomes-Tr:CAB13793" /db_xref="InterPro:IPR018958" /db_xref="SubtiList:BG13505" /db_xref="UniProtKB/Swiss-Prot:O34377" /translation="MTNFVHKTVNGLKSLLDEKGAIKLFCSEGDIMEFLVTFSQDKAT LNDIQSFEAKHQLTLPQDYQKFMTLHNGAKIFEILSDGENIGGGLQLFSLEEIEEELK YEDLFEDINGIPIGYLLEECHLMIDKDKVNQGDPNYLYIFESGLEYNPLNLNFEKFLD RYILANGEPFWDWRYYTAENYYRTR*" gene complement(2073658..2074215) /gene="yobM" /locus_tag="BSU_19010" /old_locus_tag="BSU19010" S_feature complement(2074222..2074617) /Source="Nicolas_S_feature" /locus_tag="new_2074222_2074617_c" /HighExp="M0t90, LoTm, M40t90, Lbstat, LBGstat, M9-stat, T0.30H, T2.30H, T1.0H, T2.0H" /AntisenseName="yobN" /AntisenseCor="-6.3634699133798794E-2" /AntisenseRegPval="-0.5" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.997" /TUlongSig="NA" /TUlongPSig="NA" /label="S722" promotor_-35 2074280..2074285 /Source="Nicolas_upshift_promotors" /id="U1543" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.995004995004995" /psig="0.995004995004995" /xcortree=1014 /SigmaFactorBS="ctttcaaattccaaaagatgtgaacagatcGTGATAggtgct cttttcagtGAATATAATGCAATAAATTctaaaaagaggtgcctccaaaaattgaatt c" /listShort="S723, yobN, S724" /listLong="S725, yobO, S727, S728" /label="promotor_-35" promotor_-10 2074301..2074319 /Source="Nicolas_upshift_promotors" /id="U1543" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.995004995004995" /psig="0.995004995004995" /xcortree=1014 /SigmaFactorBS="ctttcaaattccaaaagatgtgaacagatcGTGATAggtgct cttttcagtGAATATAATGCAATAAATTctaaaaagaggtgcctccaaaaattgaatt c" /listShort="S723, yobN, S724" /listLong="S725, yobO, S727, S728" /label="promotor_-10" upshifts 2074310 /Source="Nicolas_upshifts" /id="U1543" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.995004995004995" /psig="0.995004995004995" /xcortree=1014 /SigmaFactorBS="ctttcaaattccaaaagatgtgaacagatcGTGATAggtgct cttttcagtGAATATAATGCAATAAATTctaaaaagaggtgcctccaaaaattgaatt c" /listShort="S723, yobN, S724" /listLong="S725, yobO, S727, S728" S_feature 2074312..2074438 /Source="Nicolas_S_feature" /locus_tag="new_2074312_2074438" /HighExp="S3, S4, S5, S6, M9-stat, S8, S7, T5.0H, T4.0H, LoTm" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigEF" /TUshortPSig="0.995" /TUlongSig="NA" /TUlongPSig="NA" /label="S723" CDS 2074343..2075779 /gene="yobN" /locus_tag="BSU_19020" /old_locus_tag="BSU19020" /EC_number="1.4.-.-" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative amine oxidase (flavoprotein)" /protein_id="NP_389783.2" /db_xref="EnsemblGenomes-Gn:BSU19020" /db_xref="EnsemblGenomes-Tr:CAB13794" /db_xref="GOA:O34363" /db_xref="InterPro:IPR001613" /db_xref="InterPro:IPR002937" /db_xref="InterPro:IPR036188" /db_xref="SubtiList:BG13506" /db_xref="UniProtKB/Swiss-Prot:O34363" /translation="MNSLMNDDMVKIIRNGLSASQHPKHILVIGAGLSGLVSASLLKN AGHRVTILEASGRAGGRVCTLRSPFSDDLYFNAGPMRIPNNHSLTLEYIKKFKLPTNV FINRTPMDIIYANGIKTRLQVFERAPGILRYPVAPNEQGKTSEELMLSLLQPILNFIN QNPARNWRIVEEQYKNHSLSSFLNTYFSYGAIDMIGVLLDMEAYMGMSLVEVLRESIF FSSPAHFYEITGGMDLLPHAFLPQLKTNILYHQKMMKMSQGENRVTIHCQHQQTAEFT SFTADLAIVTIPFSTLRFVKVEPYHSFSYYKRRAIRELNYISATKIGIEFKSRFWEKA GQHGGKSITDLPIRFSYYPSRNIGANGHAVILASYTWADEALIWDSLSEGERIQYTLL NLSEIYGDIVWSEFVSGTSFSWSQYPYSAGGFTAFEPGQELELYPYIPVPEGRVHFAG EHASLTHAWMQGAIESGIRVAYEVNRLP*" gene 2074343..2075779 /gene="yobN" /locus_tag="BSU_19020" /old_locus_tag="BSU19020" promotor_-10 complement(2074603..2074622) /Source="Nicolas_upshift_promotors" /id="U1544" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.425574425574426" /psig="0.997002997002997" /xcortree=3167 /SigmaFactorBS="atgatgtccatcggggttctgttgataaatacattTGTTGGC aatttgaatttttTGATATATTCTAAGGTTAACgaatggttattcggtatgcgcatcg g" /listShort="S722, yobM" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2074617) /Source="Nicolas_upshifts" /id="U1544" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.425574425574426" /psig="0.997002997002997" /xcortree=3167 /SigmaFactorBS="atgatgtccatcggggttctgttgataaatacattTGTTGGC aatttgaatttttTGATATATTCTAAGGTTAACgaatggttattcggtatgcgcatcg g" /listShort="S722, yobM" /GFF_Attribute="listLong" promotor_-35 complement(2074636..2074642) /Source="Nicolas_upshift_promotors" /id="U1544" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.425574425574426" /psig="0.997002997002997" /xcortree=3167 /SigmaFactorBS="atgatgtccatcggggttctgttgataaatacattTGTTGGC aatttgaatttttTGATATATTCTAAGGTTAACgaatggttattcggtatgcgcatcg g" /listShort="S722, yobM" /GFF_Attribute="listLong" /label="promotor_-35" S_feature 2075780..2076111 /Source="Nicolas_S_feature" /locus_tag="new_2075780_2076111" /HighExp="S3, S8, S4, S5, S7, M9-stat, S6, T5.0H, C30, BT" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigEF" /TUshortPSig="0.995" /TUlongSig="NA" /TUlongPSig="NA" /label="S724" promotor_-35 2076093..2076101 /Source="Nicolas_upshift_promotors" /id="U1545" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp=1 /psig=1 /xcortree=526 /SigmaFactorBS="tttcattgacttacatttcttgaaaaccagtataaatcctAA AGGAATTttgtaacaaaTACAGAATTGGAAAGAGAAgcgccaaaagaaatgctaactc c" /listShort="S725, yobO, S727, S728" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2076112..2076130 /Source="Nicolas_upshift_promotors" /id="U1545" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp=1 /psig=1 /xcortree=526 /SigmaFactorBS="tttcattgacttacatttcttgaaaaccagtataaatcctAA AGGAATTttgtaacaaaTACAGAATTGGAAAGAGAAgcgccaaaagaaatgctaactc c" /listShort="S725, yobO, S727, S728" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 2076113..2076205 /Source="Nicolas_S_feature" /locus_tag="new_2076113_2076205" /HighExp="M9-stat, T1.30H, T2.0H, S2, T2.30H, Lbstat, BC, T0.30H, T3.30H, T3.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigH" /TUshortPSig=1 /TUlongSig="SigEF" /TUlongPSig="0.995" /label="S725" upshifts 2076113 /Source="Nicolas_upshifts" /id="U1545" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp=1 /psig=1 /xcortree=526 /SigmaFactorBS="tttcattgacttacatttcttgaaaaccagtataaatcctAA AGGAATTttgtaacaaaTACAGAATTGGAAAGAGAAgcgccaaaagaaatgctaactc c" /listShort="S725, yobO, S727, S728" /GFF_Attribute="listLong" CDS 2076206..2078626 /gene="yobO" /locus_tag="BSU_19030" /old_locus_tag="BSU19030" /function="16.5: Explore" /function="16.13: Shape" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 11562162, 19450535; Product type h: extrachromosomal origin" /codon_start=1 /transl_table=11 /product="putative phage-related pre-neck appendage protein; defective prophage 6" /protein_id="NP_389784.1" /db_xref="EnsemblGenomes-Gn:BSU19030" /db_xref="EnsemblGenomes-Tr:CAB13795" /db_xref="InterPro:IPR006626" /db_xref="InterPro:IPR011050" /db_xref="InterPro:IPR012334" /db_xref="InterPro:IPR021865" /db_xref="InterPro:IPR024535" /db_xref="SubtiList:BG13507" /db_xref="UniProtKB/Swiss-Prot:O34433" /translation="MVHFKNCPDPSLNANSQSHPEFSSELEHIKTRMQNFIKHSVTDQ NIEVTDARVTAEGEVTSLLKERLDKEYYRLLSKITREVNVADFGAVPDGRDNTEAFRK AIGNGRVKVHVPAGEYLVQGIKLPSWTTIVGQGKGITVIKLHEDTPAHEWVITNDDYQ NGNRNIFVQGMSLDWNPSRQCGVRNPGGQFSSCLTFAKVEYGWIKDVEAINAGLHGID ITSPTYDHLPDTDWTKDGSRYIWIDNCVTYGSGDDGITTHYSEYIFISNCHSGNPRGT EFAEGVSNSNGIEIDDGSRHVWLLNNFTSGNIRGVEVKAHELWPASQNVHIIGHISYR DVRAFDLRHIGHHQITDPESTTAYDVTLIDCSAVEPVFNSLYDAVTPRALVISAYKNV NVSGFTAIGDPDYDYKENPVVALQYRSQNITINGIKIRGFKKAGVDINLSGGSNKTDY IKISNFDIYKSAPKGISIGGGLYNVNILNGTMITDNGTVAIQSPNNQATILGVQSEGY SVAASIKGQTYQQVPINLKGGIQLATTSGFAVNQTSAVIAGTGDITARGERNAVISSS GGSSTEGSRALIASSNNAHIRGNQASRTILSSENIILEEPYTVAGGHQSIKWLLDSVR GNGTFAGAISSSLGGYGEYFESSTGQLIHTGTIVTLRGEKIVPANVGDYMLGVISETS AFISGASSFVWQGRYLTNEFGGFIYETVTDEESGELIRVPKQNPDYDTALEANYHSRA ARDEWHVVGLVGQHYVRIDETVNQGDYLTAHNGIGTKATEGSWKVMKITSAYTSEKGY GIALTVIK*" gene 2076206..2078626 /gene="yobO" /locus_tag="BSU_19030" /old_locus_tag="BSU19030" S_feature complement(2078548..2079183) /Source="Nicolas_S_feature" /locus_tag="new_2078548_2079183_c" /HighExp="MG 150, S8, MG 120, S7, MG 90, GM-0.1, Glu, Fru, GM-0.2, GM 5" /AntisenseName="yobO" /AntisenseCor="0.134597835896198" /AntisenseRegPval="-1.6" /CDS_PredictionProba="0.40121099999999998" /TUshortSig="SigA" /TUshortPSig="0.997" /TUlongSig="NA" /TUlongPSig="NA" /label="S726" S_feature 2078627..2079084 /Source="Nicolas_S_feature" /locus_tag="new_2078627_2079084" /HighExp="M9-stat, Lbstat, BC, T1.30H, S2, T0.30H, T2.0H, T3.0H, T2.30H, S4" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigH" /TUshortPSig=1 /TUlongSig="SigEF" /TUlongPSig="0.995" /label="S727" promotor_-35 2079059..2079066 /Source="Nicolas_upshift_promotors" /id="U1546" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.488511488511489" /psig="0.896103896103896" /xcortree=87 /SigmaFactorBS="tctaaattcatttcaccgttactaaaagtaatcCTTGCATTc cttcgccctcCATGCTATATTCATATAGCGatgagctgaattgtgtaagccgatgtac a" /listShort="S728" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2079078..2079097 /Source="Nicolas_upshift_promotors" /id="U1546" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.488511488511489" /psig="0.896103896103896" /xcortree=87 /SigmaFactorBS="tctaaattcatttcaccgttactaaaagtaatcCTTGCATTc cttcgccctcCATGCTATATTCATATAGCGatgagctgaattgtgtaagccgatgtac a" /listShort="S728" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 2079086..2079196 /Source="Nicolas_S_feature" /locus_tag="new_2079086_2079196" /HighExp="LoTm, S7, HPh, LPhT, S8, BT, S6, G/S, S0, B36" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigH" /TUshortPSig="0.896, 1" /TUlongSig="SigEF" /TUlongPSig="0.995" /label="S728" upshifts 2079086 /Source="Nicolas_upshifts" /id="U1546" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.488511488511489" /psig="0.896103896103896" /xcortree=87 /SigmaFactorBS="tctaaattcatttcaccgttactaaaagtaatcCTTGCATTc cttcgccctcCATGCTATATTCATATAGCGatgagctgaattgtgtaagccgatgtac a" /listShort="S728" /GFF_Attribute="listLong" misc_RNA 2079096..2079203 /gene="bsrF" /locus_tag="BSU_misc_RNA_75" /product="small untranslated regulatory RNA" /experiment="publication(s) with functional evidences, PMID:18948176, 19542274" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 18948176, 19542274; Product type n: RNA" gene 2079096..2079203 /gene="bsrF" /locus_tag="BSU_misc_RNA_75" downshifts 2079181 /Source="Nicolas_upshifts" /id="D1044" /incds=0 /nref=65 /ntot=254 /MaxReadThrough="1.60135" /MaxDrop="9.06442" /score="30.7999406" /energy="-13.9" /TU="NA" /idTUdmin="U1545" /TUdmin=7 /isTUend="TRUE" CDS complement(2079214..2079546) /gene="csaA" /locus_tag="BSU_19040" /old_locus_tag="BSU19040" /function="16.1: Circulate" /function="16.6: Maintain" /function="16.13: Shape" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 10658654, 10816431, 13129613, 15856219, 17372352, 28724440; Product type f : factor" /codon_start=1 /transl_table=11 /product="molecular chaperone for secreting proteins" /protein_id="NP_389785.1" /db_xref="EnsemblGenomes-Gn:BSU19040" /db_xref="EnsemblGenomes-Tr:CAB13796" /db_xref="GOA:P37584" /db_xref="InterPro:IPR002547" /db_xref="InterPro:IPR008231" /db_xref="InterPro:IPR012340" /db_xref="PDB:2NZH" /db_xref="PDB:2NZO" /db_xref="SubtiList:BG10809" /db_xref="UniProtKB/Swiss-Prot:P37584" /translation="MAVIDDFEKLDIRTGTIVKAEEFPEARVPAIKLVIDFGTEIGIK QSSAQITKRYKPEGLINKQVIAVVNFPPRRIAGFKSEVLVLGGIPGQGDVVLLQPDQP VPNGTKIG*" gene complement(2079214..2079546) /gene="csaA" /locus_tag="BSU_19040" /old_locus_tag="BSU19040" downshifts complement(2079228) /Source="Nicolas_upshifts" /id="D1045" /incds=0 /nref=28 /ntot=228 /MaxReadThrough="4.42209" /MaxDrop="5.706" /score="-8.98970984" /energy="-13.9" /TU="U1547" /idTUdmin="U1550" /TUdmin=0 /isTUend="TRUE" CDS complement(2079611..2080336) /gene="yobQ" /locus_tag="BSU_19050" /old_locus_tag="BSU19050" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 10704478, 27038276; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative transcriptional regulator (AraC/XylS family)" /protein_id="NP_389786.1" /db_xref="EnsemblGenomes-Gn:BSU19050" /db_xref="EnsemblGenomes-Tr:CAB13797" /db_xref="GOA:O34901" /db_xref="InterPro:IPR009057" /db_xref="InterPro:IPR011051" /db_xref="InterPro:IPR013096" /db_xref="InterPro:IPR014710" /db_xref="InterPro:IPR018060" /db_xref="InterPro:IPR018062" /db_xref="SubtiList:BG13508" /db_xref="UniProtKB/Swiss-Prot:O34901" /translation="MLMDSLQEIICEKRTYTRLYHSHKHAYSQFLFPLEGSIDLETEG RQVKLNPDHFLYIPPQCEHRFRSIGRNECLVLDVPLHAMKIDEYRAGSGIEAALDPFW SSIRYLLTEEAKAGTANSLHMLVQYIKEKLQSHSYASIAYIHSHLFERLTIKKLAEIE HYHPAYYSSWFKKQTGKSPQNYIADLRLEEAKRMLMERNETLTVVSEALGFQNLSSFT RWFTKSTGMPPRLYRNTLYSDKK*" gene complement(2079611..2080336) /gene="yobQ" /locus_tag="BSU_19050" /old_locus_tag="BSU19050" CDS complement(2080351..2081094) /gene="yobR" /locus_tag="BSU_19060" /old_locus_tag="BSU19060" /EC_number="2.3.1.-" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 12793527, 23944997; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative acetyltransferase" /protein_id="NP_389787.1" /db_xref="EnsemblGenomes-Gn:BSU19060" /db_xref="EnsemblGenomes-Tr:CAB13798" /db_xref="GOA:O34376" /db_xref="InterPro:IPR000182" /db_xref="InterPro:IPR016181" /db_xref="SubtiList:BG13509" /db_xref="UniProtKB/Swiss-Prot:O34376" /translation="MDDIRKIERLAAASWPAYFQKSIGKWLLRANFGVTKRANSVWTS ADMPEGDFQLEAELFYQSLGLPVCFHISNASPKGLDDALADSRYEKVDECFQMTALCR SIMSRTNDNSRFTYKWEQEPSSVWIDEFIQLEGFSPERHKGYKHIFERMPPCKTFFKM YDKESLTALGTVSVIDGYGGLSNIVVAEEHRGKGAGTQVIRVLTEWAKNNGAERMFLQ VMKENLAAVSLYGKIGFSPISEHHYRIKR*" gene complement(2080351..2081094) /gene="yobR" /locus_tag="BSU_19060" /old_locus_tag="BSU19060" promotor_-10 complement(2081122..2081141) /Source="Nicolas_upshift_promotors" /id="U1547" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.273726273726274" /psig="0.997002997002997" /xcortree=3044 /SigmaFactorBS="ttattaataaacaataaaaatattatgtaaacaaataaatGG ATGTCttatatttctgaaTATTGTATAATATCAAGGGAgtatacataggggagaggca t" /listShort="yobR, yobQ, csaA, S726" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2081141) /Source="Nicolas_upshifts" /id="U1547" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.273726273726274" /psig="0.997002997002997" /xcortree=3044 /SigmaFactorBS="ttattaataaacaataaaaatattatgtaaacaaataaatGG ATGTCttatatttctgaaTATTGTATAATATCAAGGGAgtatacataggggagaggca t" /listShort="yobR, yobQ, csaA, S726" /GFF_Attribute="listLong" promotor_-35 complement(2081155..2081161) /Source="Nicolas_upshift_promotors" /id="U1547" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.273726273726274" /psig="0.997002997002997" /xcortree=3044 /SigmaFactorBS="ttattaataaacaataaaaatattatgtaaacaaataaatGG ATGTCttatatttctgaaTATTGTATAATATCAAGGGAgtatacataggggagaggca t" /listShort="yobR, yobQ, csaA, S726" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2081172..2081747) /gene="yobS" /locus_tag="BSU_19070" /old_locus_tag="BSU19070" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative transcriptional regulator" /protein_id="NP_389788.1" /db_xref="EnsemblGenomes-Gn:BSU19070" /db_xref="EnsemblGenomes-Tr:CAB13799" /db_xref="GOA:O34892" /db_xref="InterPro:IPR001647" /db_xref="InterPro:IPR009057" /db_xref="InterPro:IPR025996" /db_xref="InterPro:IPR036271" /db_xref="SubtiList:BG13510" /db_xref="UniProtKB/Swiss-Prot:O34892" /translation="MSPRIGLTQKMIVDAAAEIADQEGVNGVSLAALSKKMNVRPPSL YNHINGLQAIRAELAVRGLTKLFDQMADSVTERKGDSAMLSLAHAYVDFAIENPGYYE AALLKVHDKRTEIVSDQIVCLVTKLLIENGYASEKTAIHATRGLRSLLHGFTVLIAKE AFEREEDILESLSFSIRTFLSGLLINNKNIM*" gene complement(2081172..2081747) /gene="yobS" /locus_tag="BSU_19070" /old_locus_tag="BSU19070" CDS complement(2081753..2082454) /gene="yobT" /locus_tag="BSU_19080" /old_locus_tag="BSU19080" /EC_number="3.-.-.-" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative metal-dependent hydrolase" /protein_id="NP_389789.1" /db_xref="EnsemblGenomes-Gn:BSU19080" /db_xref="EnsemblGenomes-Tr:CAB13800" /db_xref="GOA:O34910" /db_xref="InterPro:IPR001279" /db_xref="InterPro:IPR036866" /db_xref="SubtiList:BG13511" /db_xref="UniProtKB/Swiss-Prot:O34910" /translation="MRITQYQTVWQLTFFPALFPVNCYLVEEENEVTLIDAALPGSYK GIIQAVNQLGKPLQHILLTHAHGDHVGSLDTLAQTFPHAKVMISERDSFLLQGDTSLR QDEPQTPIKGGIPKHIQTKPHQLLTGGETIGSLLAIPTPGHTPGSMSFLDTRNGTLIA GDAFQLRGGIAVSGQIKWAFPFPAFATWNKEEAIKSAQLLADKAPSCLAVGHGKFLRS PSERMRQAIQKAKKG*" gene complement(2081753..2082454) /gene="yobT" /locus_tag="BSU_19080" /old_locus_tag="BSU19080" promotor_-10 complement(2082484..2082503) /Source="Nicolas_upshift_promotors" /id="U1548" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.896103896103896" /psig=1 /xcortree=2198 /SigmaFactorBS="cgataaaaaaataataaacTCTTGAAAaactaatggtgttaG TTAATAATAAAACTAACACcattagtttttgttaggaggaataaaaagatgagaatta c" /listShort="yobT" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2082484) /Source="Nicolas_upshifts" /id="U1548" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.896103896103896" /psig=1 /xcortree=2198 /SigmaFactorBS="cgataaaaaaataataaacTCTTGAAAaactaatggtgttaG TTAATAATAAAACTAACACcattagtttttgttaggaggaataaaaagatgagaatta c" /listShort="yobT" /GFF_Attribute="listLong" promotor_-10 complement(2082488..2082503) /Source="Nicolas_upshift_promotors" /id="U1549" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.911088911088911" /psig="0.998001998001998" /xcortree=2199 /SigmaFactorBS="aaatgccgcagtgccacagcgagcacaagttaacatttatgt agcgataaaaaaataataaacTCTTGAAAaactaatggtgttaGTTAATAATAAAACT A" /listShort="yobT" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 complement(2082518..2082525) /Source="Nicolas_upshift_promotors" /id="U1548" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.896103896103896" /psig=1 /xcortree=2198 /SigmaFactorBS="cgataaaaaaataataaacTCTTGAAAaactaatggtgttaG TTAATAATAAAACTAACACcattagtttttgttaggaggaataaaaagatgagaatta c" /listShort="yobT" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 complement(2082518..2082525) /Source="Nicolas_upshift_promotors" /id="U1549" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.911088911088911" /psig="0.998001998001998" /xcortree=2199 /SigmaFactorBS="aaatgccgcagtgccacagcgagcacaagttaacatttatgt agcgataaaaaaataataaacTCTTGAAAaactaatggtgttaGTTAATAATAAAACT A" /listShort="yobT" /GFF_Attribute="listLong" /label="promotor_-35" upshifts complement(2082528) /Source="Nicolas_upshifts" /id="U1549" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.911088911088911" /psig="0.998001998001998" /xcortree=2199 /SigmaFactorBS="aaatgccgcagtgccacagcgagcacaagttaacatttatgt agcgataaaaaaataataaacTCTTGAAAaactaatggtgttaGTTAATAATAAAACT A" /listShort="yobT" /GFF_Attribute="listLong" CDS complement(2082531..2083013) /gene="yobU" /locus_tag="BSU_19090" /old_locus_tag="BSU19090" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type f: factor" /codon_start=1 /transl_table=11 /product="putative effector of transcriptional regulator" /protein_id="NP_389790.1" /db_xref="EnsemblGenomes-Gn:BSU19090" /db_xref="EnsemblGenomes-Tr:CAB13801" /db_xref="InterPro:IPR010499" /db_xref="InterPro:IPR011256" /db_xref="InterPro:IPR029442" /db_xref="SubtiList:BG13512" /db_xref="UniProtKB/Swiss-Prot:O34637" /translation="MGFSHITHLDLKRFAGLSQRTSNALEMTEERRIPALWDQLWKQD MSALLSQAEKDKSIIALYSNYEQETNGFYTFSVGTFQEYDDILPGPYENIDLPASAYA VFTSRIGPIEEIVLETWKEIWTWDKRHLRTFTGDFEMYDQNAAVPQRAQVNIYVAIKK *" gene complement(2082531..2083013) /gene="yobU" /locus_tag="BSU_19090" /old_locus_tag="BSU19090" misc_feature complement(2083052..2083069) /Source="Nicolas_upshift_promotors" /id="U1550" /multdbtbs="-" /comp="M18" /sig="Sig-" /pcomp="0.334665334665335" /psig="0.334665334665335" /xcortree=1509 /SigmaFactorBS="ataaagtaaaagaaaccattcatcacatgcaaaaaatatatg aaaccTGACACACTGCTGTCAGGtttctttgtctataatcttaaaaaaaggaggagat c" /listShort="yobU, yobT, yobS, yobR, yobQ, csaA" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(2083056) /Source="Nicolas_upshifts" /id="U1550" /multdbtbs="-" /comp="M18" /sig="Sig-" /pcomp="0.334665334665335" /psig="0.334665334665335" /xcortree=1509 /SigmaFactorBS="ataaagtaaaagaaaccattcatcacatgcaaaaaatatatg aaaccTGACACACTGCTGTCAGGtttctttgtctataatcttaaaaaaaggaggagat c" /listShort="yobU, yobT, yobS, yobR, yobQ, csaA" /GFF_Attribute="listLong" CDS complement(2083067..2084008) /gene="yobV" /locus_tag="BSU_19100" /old_locus_tag="BSU19100" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative transcriptional regulator" /protein_id="NP_389791.1" /db_xref="EnsemblGenomes-Gn:BSU19100" /db_xref="EnsemblGenomes-Tr:CAB13802" /db_xref="GOA:O34920" /db_xref="InterPro:IPR001034" /db_xref="InterPro:IPR013196" /db_xref="InterPro:IPR026881" /db_xref="InterPro:IPR028349" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG13513" /db_xref="UniProtKB/Swiss-Prot:O34920" /translation="MKLERLLAMVVLLISKKQVQAAELAELFEVSVRTIYRDIETINR AGIPIVTSQGSGGGIGIMETYRLEREWLKEEELFAIASALQSVSSMYEPVSHSTAYQK IKHLIPEQSTQAFKHQTEKWFIDMTAWGHTEDQKTLREKISAAIDRLLTISFTYTSAS GETLLRETEPYTLVCKAGHWYLYAYCLVRNDFRFFKLNRMKDLAILHQTFIRKDIQLD TLPWDKSWYQKDRLTELVILVQPSARQRIGEWFGYDVLHCCEEDEICQAVISLPEDQW LIGFLLQFGKDIEVLQPLHIRDKVKETIHHMQKIYET*" gene complement(2083067..2084008) /gene="yobV" /locus_tag="BSU_19100" /old_locus_tag="BSU19100" downshifts complement(2083100) /Source="Nicolas_upshifts" /id="D1046" /incds=0 /nref=4 /ntot=33 /MaxReadThrough="0.95712" /MaxDrop="3.62763" /score="-3.71616684" /energy="-9" /TU="NA" /idTUdmin="U1548" /TUdmin="-770" /isTUend="FALSE" promotor_-10 complement(2084038..2084057) /Source="Nicolas_upshift_promotors" /id="U1551" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.615384615384615" /psig="0.971028971028971" /xcortree=3116 /SigmaFactorBS="tatgcgaggtgtattccgccgcataatagatATGCCcaagct ttatcaaAATGTTATGATTGTTTTGTTggaaaatacaagaagaaaaggtgcgcagaat g" /listShort="yobV" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2084046) /Source="Nicolas_upshifts" /id="U1551" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.615384615384615" /psig="0.971028971028971" /xcortree=3116 /SigmaFactorBS="tatgcgaggtgtattccgccgcataatagatATGCCcaagct ttatcaaAATGTTATGATTGTTTTGTTggaaaatacaagaagaaaaggtgcgcagaat g" /listShort="yobV" /GFF_Attribute="listLong" promotor_-35 complement(2084071..2084075) /Source="Nicolas_upshift_promotors" /id="U1551" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.615384615384615" /psig="0.971028971028971" /xcortree=3116 /SigmaFactorBS="tatgcgaggtgtattccgccgcataatagatATGCCcaagct ttatcaaAATGTTATGATTGTTTTGTTggaaaatacaagaagaaaaggtgcgcagaat g" /listShort="yobV" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 2084079..2084088 /Source="Nicolas_upshift_promotors" /id="U1552" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=1341 /SigmaFactorBS="cataacattttgataaagcttgggcatatcTATTATGCGGcg gaatacacctCGCATATGCTATGAAAACAGgggtttccccttcttttttgtgttcagt a" /listShort="S729, yobW" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2084101..2084120 /Source="Nicolas_upshift_promotors" /id="U1552" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=1341 /SigmaFactorBS="cataacattttgataaagcttgggcatatcTATTATGCGGcg gaatacacctCGCATATGCTATGAAAACAGgggtttccccttcttttttgtgttcagt a" /listShort="S729, yobW" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2084109 /Source="Nicolas_upshifts" /id="U1552" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=1341 /SigmaFactorBS="cataacattttgataaagcttgggcatatcTATTATGCGGcg gaatacacctCGCATATGCTATGAAAACAGgggtttccccttcttttttgtgttcagt a" /listShort="S729, yobW" /GFF_Attribute="listLong" S_feature 2084124..2084188 /Source="Nicolas_S_feature" /locus_tag="new_2084124_2084188" /HighExp="BT, S7, B36, S8, S6, Pyr, G/S, B60, Glucon, G135" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigK" /TUshortPSig="0.997" /TUlongSig="NA" /TUlongPSig="NA" /label="S729" promotor_-35 2084160..2084165 /Source="Nicolas_upshift_promotors" /id="U1553" /multdbtbs="SigK" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1008 /SigmaFactorBS="cttcttttttgtgttcagtatttatttcagCTACTAtttccg accggataaGCATACACTTCTCAACGGAggggatttcacatcatgcatcttacacttc a" /listShort="yobW" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2084181..2084199 /Source="Nicolas_upshift_promotors" /id="U1553" /multdbtbs="SigK" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1008 /SigmaFactorBS="cttcttttttgtgttcagtatttatttcagCTACTAtttccg accggataaGCATACACTTCTCAACGGAggggatttcacatcatgcatcttacacttc a" /listShort="yobW" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2084190 /Source="Nicolas_upshifts" /id="U1553" /multdbtbs="SigK" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1008 /SigmaFactorBS="cttcttttttgtgttcagtatttatttcagCTACTAtttccg accggataaGCATACACTTCTCAACGGAggggatttcacatcatgcatcttacacttc a" /listShort="yobW" /GFF_Attribute="listLong" CDS 2084214..2084759 /gene="yobW" /locus_tag="BSU_19110" /old_locus_tag="BSU19110" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:8990290, 11717295, 15849754, 16850406" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8990290, 11717295, 15849754, 16850406; Product type f: factor" /codon_start=1 /transl_table=11 /product="mother cell-specific membrane sporulation protein" /protein_id="NP_389792.1" /db_xref="EnsemblGenomes-Gn:BSU19110" /db_xref="EnsemblGenomes-Tr:CAB13803" /db_xref="GOA:P94497" /db_xref="InterPro:IPR014743" /db_xref="SubtiList:BG12269" /db_xref="UniProtKB/Swiss-Prot:P94497" /translation="MHLTLQSVYPAIIIIFFLYKKIKRSIGYQPLKPRWLFTRIILFS LFAFGLSIFSAIHPFLYGYLILGILGGWLLVFFAKKNISFEKRRGKIYFRTHIWVEVI LLTLFLSRFLYRVTELYLTSPDLNRLGSYSQSIGTDPLTIGVCFLIAVYYIGFSSFII KLSRNELEQHEYNKEKDILAR*" gene 2084214..2084759 /gene="yobW" /locus_tag="BSU_19110" /old_locus_tag="BSU19110" downshifts 2084718 /Source="Nicolas_upshifts" /id="D1047" /incds=0 /nref=20 /ntot=63 /MaxReadThrough="3.56215" /MaxDrop="4.5413" /score="-4.21976438" /energy="-17.7" /TU="U1552,U1553" /idTUdmin="U1552" /TUdmin="-132" /isTUend="FALSE" CDS complement(2084786..2085109) /gene="czrA" /locus_tag="BSU_19120" /old_locus_tag="BSU19120" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:15948947, 16406068, 16430705, 19170879, 19995076, 25213752" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15948947, 16406068, 16430705, 19170879, 19995076, 25213752; Product type r : regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator (multiple metal-sensing ArsR-SmtB transcriptional repressor favouring Zn2+)" /protein_id="NP_389793.1" /db_xref="EnsemblGenomes-Gn:BSU19120" /db_xref="EnsemblGenomes-Tr:CAB13804" /db_xref="GOA:O31844" /db_xref="InterPro:IPR001845" /db_xref="InterPro:IPR011991" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG13748" /db_xref="UniProtKB/Swiss-Prot:O31844" /translation="MTEFRETEQSAADLDEETLFLVAQTFKALSDPTRIRILHLLSQG EHAVNGIAEKLNLLQSTVSHQLRFLKNLRLVKSRREGTSIYYSPEDEHVLDVLQQMIH HTQHD*" gene complement(2084786..2085109) /gene="czrA" /locus_tag="BSU_19120" /old_locus_tag="BSU19120" downshifts complement(2084793) /Source="Nicolas_upshifts" /id="D1048" /incds=0 /nref=73 /ntot=252 /MaxReadThrough="1.89304" /MaxDrop="4.873" /score="17.3750937" /energy="-18.6" /TU="NA" /idTUdmin="U1554" /TUdmin="-21" /isTUend="TRUE" promotor_-10 complement(2085130..2085149) /Source="Nicolas_upshift_promotors" /id="U1554" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.462537462537463" /psig="0.999000999001" /xcortree=2223 /SigmaFactorBS="actatgagattgaaatggaatacaagcaggctGGTTTGCAct caagcgcattTGTTATAAGATAAAACTATGaataaagaaaggtgatacatatgactga a" /listShort="czrA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2085141) /Source="Nicolas_upshifts" /id="U1554" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.462537462537463" /psig="0.999000999001" /xcortree=2223 /SigmaFactorBS="actatgagattgaaatggaatacaagcaggctGGTTTGCAct caagcgcattTGTTATAAGATAAAACTATGaataaagaaaggtgatacatatgactga a" /listShort="czrA" /GFF_Attribute="listLong" promotor_-35 complement(2085162..2085169) /Source="Nicolas_upshift_promotors" /id="U1554" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.462537462537463" /psig="0.999000999001" /xcortree=2223 /SigmaFactorBS="actatgagattgaaatggaatacaagcaggctGGTTTGCAct caagcgcattTGTTATAAGATAAAACTATGaataaagaaaggtgatacatatgactga a" /listShort="czrA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 2085230..2085236 /Source="Nicolas_upshift_promotors" /id="U1555" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.444555444555445" /psig="0.994005994005994" /xcortree=3129 /SigmaFactorBS="tttcaatctcatagtttaaatttatgtttcaaatcaggtttt tACTTGGTctgatataccctctTATGTCATAATAAAAAAGGTcatactgctccaaaca t" /listShort="yocA" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 2085247 /Source="Nicolas_upshifts" /id="U1555" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.444555444555445" /psig="0.994005994005994" /xcortree=3129 /SigmaFactorBS="tttcaatctcatagtttaaatttatgtttcaaatcaggtttt tACTTGGTctgatataccctctTATGTCATAATAAAAAAGGTcatactgctccaaaca t" /listShort="yocA" /GFF_Attribute="listLong" promotor_-10 2085251..2085270 /Source="Nicolas_upshift_promotors" /id="U1555" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.444555444555445" /psig="0.994005994005994" /xcortree=3129 /SigmaFactorBS="tttcaatctcatagtttaaatttatgtttcaaatcaggtttt tACTTGGTctgatataccctctTATGTCATAATAAAAAAGGTcatactgctccaaaca t" /listShort="yocA" /GFF_Attribute="listLong" /label="promotor_-10" CDS 2085303..2085980 /gene="yocA" /locus_tag="BSU_19130" /old_locus_tag="BSU19130" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 14563871, 20400549; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative murein fragments glycosidase" /protein_id="NP_389794.1" /db_xref="EnsemblGenomes-Gn:BSU19130" /db_xref="EnsemblGenomes-Tr:CAB13805" /db_xref="GOA:O34636" /db_xref="InterPro:IPR023346" /db_xref="SubtiList:BG13514" /db_xref="UniProtKB/Swiss-Prot:O34636" /translation="MKKKRKGCFAAAGFMMIFVFVIASFLLVLLFFNRDLIKKLPIDT KTIVLERLTDYKPLVEEELESQGLSNYTSLILGMMYQESKGKGNDPMQSSESLGLKRN EITDPQLSVKQGIKQFTLMYKTGKEKGVDLDTIIQSYNMGAGYIDFVAEHGGTHTEEL AKQYSEQQVKKNPDLYTCGGNAKNFRYPYCYGDYTYAEKVKEKTKTVEESLQVATLET MESKAHE*" gene 2085303..2085980 /gene="yocA" /locus_tag="BSU_19130" /old_locus_tag="BSU19130" downshifts 2085972 /Source="Nicolas_upshifts" /id="D1049" /incds=0 /nref=207 /ntot=268 /MaxReadThrough="3.9729" /MaxDrop="8.52704" /score="-4.21976438" /energy="-17.7" /TU="U1555" /idTUdmin="U1555" /TUdmin="-44" /isTUend="FALSE" CDS complement(2086070..2086606) /gene="yozB" /locus_tag="BSU_19140" /old_locus_tag="BSU19140" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406, 19222757, 24214949; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative integral inner membrane protein" /protein_id="NP_389795.1" /db_xref="EnsemblGenomes-Gn:BSU19140" /db_xref="EnsemblGenomes-Tr:CAB13806" /db_xref="GOA:O31845" /db_xref="InterPro:IPR007352" /db_xref="InterPro:IPR013833" /db_xref="SubtiList:BG13749" /db_xref="UniProtKB/Swiss-Prot:O31845" /translation="MNQTENKPKNYTGIVLTLTVLINGLIAVLFFMPKLDQFSHANIH ILPMLNAIFNSFTFIFLLAALIMIKQKNIKAHKRFILAAFTTTLLFLICYVTYHSIAE NTLYGGEGIMRPIYFFILITHICLSAIIVPLALFTLIRGFSMQVERHKKIARWTMPLW LYVSLTGVIVYLMISPYY*" gene complement(2086070..2086606) /gene="yozB" /locus_tag="BSU_19140" /old_locus_tag="BSU19140" downshifts complement(2086093) /Source="Nicolas_upshifts" /id="D1050" /incds=0 /nref=175 /ntot=250 /MaxReadThrough="4.33842" /MaxDrop="7.96098" /score="14.7470642" /energy="-7.7" /TU="U1556" /idTUdmin="U1557" /TUdmin="-1" /isTUend="TRUE" promotor_-10 complement(2086633..2086652) /Source="Nicolas_upshift_promotors" /id="U1556" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.824175824175824" /psig="0.99000999000999" /xcortree=1607 /SigmaFactorBS="gcctttgaagtgtgtctaatttctgacgaagcaatcgaaaCC GTTGACatcttctttgaatTTGCATACGATTTGGATAGCcagtacaaattaggagagg t" /listShort="yozB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2086653) /Source="Nicolas_upshifts" /id="U1556" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.824175824175824" /psig="0.99000999000999" /xcortree=1607 /SigmaFactorBS="gcctttgaagtgtgtctaatttctgacgaagcaatcgaaaCC GTTGACatcttctttgaatTTGCATACGATTTGGATAGCcagtacaaattaggagagg t" /listShort="yozB" /GFF_Attribute="listLong" promotor_-35 complement(2086666..2086673) /Source="Nicolas_upshift_promotors" /id="U1556" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.824175824175824" /psig="0.99000999000999" /xcortree=1607 /SigmaFactorBS="gcctttgaagtgtgtctaatttctgacgaagcaatcgaaaCC GTTGACatcttctttgaatTTGCATACGATTTGGATAGCcagtacaaattaggagagg t" /listShort="yozB" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2086743..2087525) /gene="yocB" /locus_tag="BSU_19150" /old_locus_tag="BSU19150" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 11717291, 16291680" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_389796.1" /db_xref="EnsemblGenomes-Gn:BSU19150" /db_xref="EnsemblGenomes-Tr:CAB13807" /db_xref="SubtiList:BG13515" /db_xref="UniProtKB/Swiss-Prot:O34516" /translation="MAIDSLINKLQYVQLEPPDKILSLYLNTDMRDPEQQGGEWKIAL KSGFSRLKEYLAASDPEEEKCLDGIRAKMNQYLNAMGKDMPRSLVFFVSDSGIWEPIK LQVPVDTRFYWEETAVLDQLKGLRQTYPSTAFILTQQHEVKIIETVLGKIEAVERYEY DMINESWKNSHSAVDKAPPFEENRMREHVTENQSRLYKRLAASLDQKAAAKRWERMVI AGDKETADILDQHMNKPIHSKIQKNLLNENEHKVIEHLIKEA*" gene complement(2086743..2087525) /gene="yocB" /locus_tag="BSU_19150" /old_locus_tag="BSU19150" downshifts complement(2086752) /Source="Nicolas_upshifts" /id="D1051" /incds=0 /nref=3 /ntot=38 /MaxReadThrough="5.37496" /MaxDrop="4.00348" /score="14.7470642" /energy="-7.7" /TU="U1557" /idTUdmin="U1557" /TUdmin="-660" /isTUend="FALSE" promotor_-10 complement(2087547..2087565) /Source="Nicolas_upshift_promotors" /id="U1557" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=229 /SigmaFactorBS="aaacaacaattccattattactagaaattagcggaaagtcaG GTTTGAtcgtttttaagagAGGAAAAAGAAAACTAACCtgtgaaaaaggaggaatcgg a" /listShort="yocB, yozB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2087566) /Source="Nicolas_upshifts" /id="U1557" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=229 /SigmaFactorBS="aaacaacaattccattattactagaaattagcggaaagtcaG GTTTGAtcgtttttaagagAGGAAAAAGAAAACTAACCtgtgaaaaaggaggaatcgg a" /listShort="yocB, yozB" /GFF_Attribute="listLong" promotor_-35 complement(2087579..2087585) /Source="Nicolas_upshift_promotors" /id="U1557" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=229 /SigmaFactorBS="aaacaacaattccattattactagaaattagcggaaagtcaG GTTTGAtcgtttttaagagAGGAAAAAGAAAACTAACCtgtgaaaaaggaggaatcgg a" /listShort="yocB, yozB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 2087622..2087629 /Source="Nicolas_upshift_promotors" /id="U1558" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.954045954045954" /psig=1 /xcortree=2435 /SigmaFactorBS="actttccgctaatttctagtaataatggaattgtTGTTTACA atacgcctctcttcTAATACAATTGGTAACTGTGtttctaagctgttttttgaaagga g" /listShort="yocC, yocD" /listLong="des, S730, desK, desR" /label="promotor_-35" promotor_-10 2087644..2087663 /Source="Nicolas_upshift_promotors" /id="U1558" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.954045954045954" /psig=1 /xcortree=2435 /SigmaFactorBS="actttccgctaatttctagtaataatggaattgtTGTTTACA atacgcctctcttcTAATACAATTGGTAACTGTGtttctaagctgttttttgaaagga g" /listShort="yocC, yocD" /listLong="des, S730, desK, desR" /label="promotor_-10" upshifts 2087648 /Source="Nicolas_upshifts" /id="U1558" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.954045954045954" /psig=1 /xcortree=2435 /SigmaFactorBS="actttccgctaatttctagtaataatggaattgtTGTTTACA atacgcctctcttcTAATACAATTGGTAACTGTGtttctaagctgttttttgaaagga g" /listShort="yocC, yocD" /listLong="des, S730, desK, desR" CDS 2087696..2088193 /gene="yocC" /locus_tag="BSU_19160" /old_locus_tag="BSU19160" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 14563871" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_389797.1" /db_xref="EnsemblGenomes-Gn:BSU19160" /db_xref="EnsemblGenomes-Tr:CAB13808" /db_xref="InterPro:IPR016181" /db_xref="SubtiList:BG13516" /db_xref="UniProtKB/Swiss-Prot:O35042" /translation="MFTVKEKNRQELEEELNDLEFQIYRMQENMKDLSKDAKVLGIDQ SKHDEWMIVSSIDDGQTCKIMLTDCKTAYRGKGCFSLVASYKDDAIHIGDIKGPPNHG FGSICMKYLKDIARDHNIPKVTGDIAKRDWNHVDRLIHFYEKHHFKVCIDHDTQSGSI KWVDL*" gene 2087696..2088193 /gene="yocC" /locus_tag="BSU_19160" /old_locus_tag="BSU19160" promotor_-35 2088200..2088203 /Source="Nicolas_upshift_promotors" /id="U1559" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.314685314685315" /psig="0.984015984015984" /xcortree=3013 /SigmaFactorBS="caatccggcagcattaagtgggttgatttgtaaaaaagtCTG GaagaaagagccaagaTATGCTGTAATGGTATAAAAccattgatggagggttctatgt a" /listShort="yocD" /listLong="des, S730, desK, desR" /label="promotor_-35" promotor_-10 2088219..2088238 /Source="Nicolas_upshift_promotors" /id="U1559" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.314685314685315" /psig="0.984015984015984" /xcortree=3013 /SigmaFactorBS="caatccggcagcattaagtgggttgatttgtaaaaaagtCTG GaagaaagagccaagaTATGCTGTAATGGTATAAAAccattgatggagggttctatgt a" /listShort="yocD" /listLong="des, S730, desK, desR" /label="promotor_-10" upshifts 2088221 /Source="Nicolas_upshifts" /id="U1559" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.314685314685315" /psig="0.984015984015984" /xcortree=3013 /SigmaFactorBS="caatccggcagcattaagtgggttgatttgtaaaaaagtCTG GaagaaagagccaagaTATGCTGTAATGGTATAAAAccattgatggagggttctatgt a" /listShort="yocD" /listLong="des, S730, desK, desR" CDS 2088257..2089234 /gene="yocD" /locus_tag="BSU_19170" /old_locus_tag="BSU19170" /EC_number="3.4.17.-" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 22516613; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative carboxypeptidase; aminoacid adenylate hydrolase (microcin resistance)" /protein_id="NP_389798.1" /db_xref="EnsemblGenomes-Gn:BSU19170" /db_xref="EnsemblGenomes-Tr:CAB13809" /db_xref="GOA:O35046" /db_xref="InterPro:IPR003507" /db_xref="InterPro:IPR027461" /db_xref="InterPro:IPR027478" /db_xref="InterPro:IPR029062" /db_xref="SubtiList:BG13517" /db_xref="UniProtKB/Swiss-Prot:O35046" /translation="MYASKLKKGDEIRIVSPATSMSILSNEAKIQAKTALERLGYRVT IAEHANECNEFDSSSIESRVHDLHAAFFDPGVKAILTTLGGFNSNQLLRYLDYEKIKR HPKILCGYSDITALCNAIYQKTGLVTYSGPHFSTFAMKKGLDYTEEYFLSCCASDDPF EIHPSSEWSDDRWFLDQENRRFYPNNGPVVIQEGYAEGTLIGGNLCTLNLLQGTEYFP ETEHTILLIEDDYMSDIHMFDRDLQSLIHLPAFSHVKAILIGRFQKASNVSIDLVKAM IETKKELSGIPIIANINAGHTSPIATFPIGGTCRIEAISGTSRIWIDKH*" gene 2088257..2089234 /gene="yocD" /locus_tag="BSU_19170" /old_locus_tag="BSU19170" downshifts 2089206 /Source="Nicolas_upshifts" /id="D1052" /incds=0 /nref=131 /ntot=256 /MaxReadThrough="3.77491" /MaxDrop="4.2254" /score="1.66373432" /energy="-9.5" /TU="U1558,U1559" /idTUdmin="U1558" /TUdmin="-132" /isTUend="FALSE" promotor_-35 2089331..2089338 /Source="Nicolas_upshift_promotors" /id="U1560" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.503496503496504" /psig="0.85914085914086" /xcortree=311 /SigmaFactorBS="acaaatgtcatataggaggcatgatgtgtgcTACTACAAaag acttctctcatTAGCGTATACTGAACCGAGAcacacaatgagaggatacttactatga c" /listShort="des, S730, desK, desR" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2089353..2089372 /Source="Nicolas_upshift_promotors" /id="U1560" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.503496503496504" /psig="0.85914085914086" /xcortree=311 /SigmaFactorBS="acaaatgtcatataggaggcatgatgtgtgcTACTACAAaag acttctctcatTAGCGTATACTGAACCGAGAcacacaatgagaggatacttactatga c" /listShort="des, S730, desK, desR" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2089360 /Source="Nicolas_upshifts" /id="U1560" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.503496503496504" /psig="0.85914085914086" /xcortree=311 /SigmaFactorBS="acaaatgtcatataggaggcatgatgtgtgcTACTACAAaag acttctctcatTAGCGTATACTGAACCGAGAcacacaatgagaggatacttactatga c" /listShort="des, S730, desK, desR" /GFF_Attribute="listLong" CDS 2089396..2090454 /gene="desE" /locus_tag="BSU_19180" /old_locus_tag="BSU19180" /EC_number="1.14.19.-" /function="16.8: Protect" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:9555904, 11717295, 12207704, 15247225, 15711796, 16105701, 28546427" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9555904, 11717295, 12207704, 15247225, 15711796, 16105701, 28546427; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="fatty acid desaturase" /protein_id="NP_389799.1" /db_xref="EnsemblGenomes-Gn:BSU19180" /db_xref="EnsemblGenomes-Tr:CAB13810" /db_xref="GOA:O34653" /db_xref="InterPro:IPR005804" /db_xref="SubtiList:BG13518" /db_xref="UniProtKB/Swiss-Prot:O34653" /translation="MTEQTIAHKQKQLTKQVAAFAQPETKNSLIQLLNTFIPFFGLWF LAYLSLDVSYLLTLALTVIAAGFLTRIFIIFHDCCHQSFFKQKRYNHILGFLTGVLTL FPYLQWQHSHSIHHATSSNLDKRGTGDIWMLTVNEYKAASRRTKLAYRLYRNPFIMFI LGPIYVFLITNRFNKKGARRKERVNTYLTNLAIVALAAACCLIFGWQSFLLVQGPIFL ISGSIGVWLFYVQHTFEDSYFEADENWSYVQAAVEGSSFYKLPKLLQWLTGNIGYHHV HHLSPKVPNYKLEVAHEHHEPLKNVPTITLKTSLQSLAFRLWDEDNKQFVSFRAIKHI PVSLPPDSPEKQKLRKNA*" gene 2089396..2090454 /gene="desE" /locus_tag="BSU_19180" /old_locus_tag="BSU19180" S_feature 2090455..2090524 /Source="Nicolas_S_feature" /locus_tag="new_2090455_2090524" /HighExp="Cold, S8, LoTm, Sw, Paraq, BC, S7, S0, Oxctl, T3.30H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.859" /TUlongSig="SigA, SigA" /TUlongPSig="0.984, 1" /label="S730" promotor_-35 2090508..2090514 /Source="Nicolas_upshift_promotors" /id="U1561" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.97002997002997" /psig="0.999000999001" /xcortree=3111 /SigmaFactorBS="gtcttctaatatactagaaggcttcctttttattgttggagg GTGCATTctggctttcacAATGATAAAGTTACAAGTAAgatgaaaagctgaaaatgag g" /listShort="desK, desR" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2090526..2090545 /Source="Nicolas_upshift_promotors" /id="U1561" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.97002997002997" /psig="0.999000999001" /xcortree=3111 /SigmaFactorBS="gtcttctaatatactagaaggcttcctttttattgttggagg GTGCATTctggctttcacAATGATAAAGTTACAAGTAAgatgaaaagctgaaaatgag g" /listShort="desK, desR" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2090526 /Source="Nicolas_upshifts" /id="U1561" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.97002997002997" /psig="0.999000999001" /xcortree=3111 /SigmaFactorBS="gtcttctaatatactagaaggcttcctttttattgttggagg GTGCATTctggctttcacAATGATAAAGTTACAAGTAAgatgaaaagctgaaaatgag g" /listShort="desK, desR" /GFF_Attribute="listLong" CDS 2090574..2091686 /gene="desK" /locus_tag="BSU_19190" /old_locus_tag="BSU19190" /function="16.3: Control" /function="16.12: Sense" /experiment="publication(s) with functional evidences, PMID:11285232, 11717295, 12207704, 14734164, 15090506, 15711796, 23356219, 24574048, 26172072, 28475313" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11285232, 11717295, 12207704, 14734164, 15090506, 15711796, 23356219, 24574048, 26172072, 28475313; Product type rc: receptor" /codon_start=1 /transl_table=11 /product="two-component thermosensor histidine kinase [DesR-DesK]" /protein_id="NP_389800.1" /db_xref="EnsemblGenomes-Gn:BSU19190" /db_xref="EnsemblGenomes-Tr:CAB13811" /db_xref="GOA:O34757" /db_xref="InterPro:IPR003594" /db_xref="InterPro:IPR011712" /db_xref="InterPro:IPR036890" /db_xref="PDB:3EHF" /db_xref="PDB:3EHG" /db_xref="PDB:3EHH" /db_xref="PDB:3EHJ" /db_xref="PDB:3GIE" /db_xref="PDB:3GIF" /db_xref="PDB:3GIG" /db_xref="PDB:5IUJ" /db_xref="PDB:5IUK" /db_xref="PDB:5IUL" /db_xref="PDB:5IUM" /db_xref="PDB:5IUN" /db_xref="SubtiList:BG13519" /db_xref="UniProtKB/Swiss-Prot:O34757" /translation="MIKNHFTFQKLNGITPYIWTIFFILPFYFIWKSSSTFVIIVGII LTLLFFSVYRFAFVSKGWTIYLWGFLLIGISTASITLFSYIYFAFFIAYFIGNIKERV PFHILYYVHLISAAVAANFSLVLKKEFFLTQIPFVVITLISAILLPFSIKSRKERERL EEKLEDANERIAELVKLEERQRIARDLHDTLGQKLSLIGLKSDLARKLIYKDPEQAAR ELKSVQQTARTSLNEVRKIVSSMKGIRLKDELINIKQILEAADIMFIYEEEKWPENIS LLNENILSMCLKEAVTNVVKHSQAKTCRVDIQQLWKEVVITVSDDGTFKGEENSFSKG HGLLGMRERLEFANGSLHIDTENGTKLTMAIPNNSK*" gene 2090574..2091686 /gene="desK" /locus_tag="BSU_19190" /old_locus_tag="BSU19190" CDS 2091705..2092304 /gene="desR" /locus_tag="BSU_19200" /old_locus_tag="BSU19200" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:11285232, 11717295, 12207704, 14734164, 15090506, 15711796, 19595746, 20581210, 24574048" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11285232, 11717295, 12207704, 14734164, 15090506, 15711796, 19595746, 20581210, 24574048; Product type r: regulator" /codon_start=1 /transl_table=11 /product="two-component response regulator [DesK]" /protein_id="NP_389801.1" /db_xref="EnsemblGenomes-Gn:BSU19200" /db_xref="EnsemblGenomes-Tr:CAB13812" /db_xref="GOA:O34723" /db_xref="InterPro:IPR000792" /db_xref="InterPro:IPR001789" /db_xref="InterPro:IPR011006" /db_xref="InterPro:IPR016032" /db_xref="InterPro:IPR036388" /db_xref="PDB:4LDZ" /db_xref="PDB:4LE0" /db_xref="PDB:4LE1" /db_xref="PDB:4LE2" /db_xref="PDB:5IUJ" /db_xref="PDB:5IUK" /db_xref="PDB:5IUL" /db_xref="PDB:5IUN" /db_xref="SubtiList:BG13520" /db_xref="UniProtKB/Swiss-Prot:O34723" /translation="MISIFIAEDQQMLLGALGSLLNLEDDMEVVGKGTTGQDAVDFVK KRQPDVCIMDIEMPGKTGLEAAEELKDTGCKIIILTTFARPGYFQRAIKAGVKGYLLK DSPSEELANAIRSVMNGKRIYAPELMEDLYSEANPLTDREKEVLELVADGKNTKEIAQ ELSIKSGTVRNYISMILEKLEVKNRIEAITRSKEKGWFK*" gene 2091705..2092304 /gene="desR" /locus_tag="BSU_19200" /old_locus_tag="BSU19200" downshifts 2092242 /Source="Nicolas_upshifts" /id="D1053" /incds=1 /nref=1 /ntot=41 /MaxReadThrough="4.44811" /MaxDrop="2.78724" /score="23.648858" /energy="-15.4" /TU="U1560" /idTUdmin="U1560" /TUdmin="-44" /isTUend="FALSE" downshifts 2092286 /Source="Nicolas_upshifts" /id="D1054" /incds=0 /nref=1 /ntot=68 /MaxReadThrough="1.88273" /MaxDrop="3.38398" /score="23.648858" /energy="-15.4" /TU="NA" /idTUdmin="U1560" /TUdmin=0 /isTUend="TRUE" S_feature complement(2092326..2092824) /Source="Nicolas_S_feature" /locus_tag="new_2092326_2092824_c" /HighExp="S4, LoTm, S6, S3, S5, S8, S7, B36, T5.0H, B60" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.230296" /TUshortSig="SigEF" /TUshortPSig="0.993" /TUlongSig="NA" /TUlongPSig="NA" /label="S731" downshifts complement(2092362) /Source="Nicolas_upshifts" /id="D1055" /incds=0 /nref=3 /ntot=21 /MaxReadThrough="1.62146" /MaxDrop="5.61121" /score="23.7393309" /energy="-12.4" /TU="NA" /idTUdmin="U1563" /TUdmin=0 /isTUend="TRUE" promotor_-35 2092796..2092805 /Source="Nicolas_upshift_promotors" /id="U1562" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1329 /SigmaFactorBS="tcttttaacccgagagcccctgaatcgcacataaagaaaAAC GGGACCActttcttttatcAGCATATGATATAAACAGCTctaagcagaacaaaaaaag a" /listShort="S732, S733" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(2092808..2092826) /Source="Nicolas_upshift_promotors" /id="U1563" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.993006993006993" /psig="0.993006993006993" /xcortree=1169 /SigmaFactorBS="ataaaagacataagcttttggcttgtgtctttttttGTTCTG cttagagctgtttataTCATATGCTGATAAAAGAAagtggtcccgtttttctttatgt g" /listShort="S731" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 2092817..2093011 /Source="Nicolas_S_feature" /locus_tag="new_2092817_2093011" /HighExp="S6, S8, S7, BT, B36, Pyr, G/S, C30, S5, B60" /AntisenseName="yocH" /AntisenseCor="0.113870403460631" /AntisenseRegPval="-1.2" /CDS_PredictionProba="NA" /TUshortSig="SigK" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S732" upshifts 2092817 /Source="Nicolas_upshifts" /id="U1562" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1329 /SigmaFactorBS="tcttttaacccgagagcccctgaatcgcacataaagaaaAAC GGGACCActttcttttatcAGCATATGATATAAACAGCTctaagcagaacaaaaaaag a" /listShort="S732, S733" /GFF_Attribute="listLong" promotor_-10 2092818..2092837 /Source="Nicolas_upshift_promotors" /id="U1562" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1329 /SigmaFactorBS="tcttttaacccgagagcccctgaatcgcacataaagaaaAAC GGGACCActttcttttatcAGCATATGATATAAACAGCTctaagcagaacaaaaaaag a" /listShort="S732, S733" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2092824) /Source="Nicolas_upshifts" /id="U1563" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.993006993006993" /psig="0.993006993006993" /xcortree=1169 /SigmaFactorBS="ataaaagacataagcttttggcttgtgtctttttttGTTCTG cttagagctgtttataTCATATGCTGATAAAAGAAagtggtcccgtttttctttatgt g" /listShort="S731" /GFF_Attribute="listLong" promotor_-35 complement(2092843..2092848) /Source="Nicolas_upshift_promotors" /id="U1563" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.993006993006993" /psig="0.993006993006993" /xcortree=1169 /SigmaFactorBS="ataaaagacataagcttttggcttgtgtctttttttGTTCTG cttagagctgtttataTCATATGCTGATAAAAGAAagtggtcccgtttttctttatgt g" /listShort="S731" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2092899..2093762) /gene="walL" /locus_tag="BSU_19210" /old_locus_tag="BSU19210" /EC_number="3.2.1.-" /function="16.6: Maintain" /function="16.8: Protect" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:17307850, 20070526, 20487291, 26102633" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 17307850, 20070526, 20487291, 26102633; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="exported cell wall lytic enzyme" /protein_id="NP_389802.1" /db_xref="EnsemblGenomes-Gn:BSU19210" /db_xref="EnsemblGenomes-Tr:CAB13813" /db_xref="GOA:O34669" /db_xref="InterPro:IPR010611" /db_xref="InterPro:IPR018392" /db_xref="InterPro:IPR036779" /db_xref="InterPro:IPR036908" /db_xref="SubtiList:BG13521" /db_xref="UniProtKB/Swiss-Prot:O34669" /translation="MKKTIMSFVAVAALSTTAFGAHASAKEITVQKGDTLWGISQKNG VNLKDLKEWNKLTSDKIIAGEKLTISSEETTTTGQYTIKAGDTLSKIAQKFGTTVNNL KVWNNLSSDMIYAGSTLSVKGQATAANTATENAQTNAPQAAPKQEAVQKEQPKQEAVQ QQPKQETKAEAETSVNTEEKAVQSNTNNQEASKELTVTATAYTANDGGISGVTATGID LNKNPNAKVIAVDPNVIPLGSKVYVEGYGEATAADTGGAIKGNKIDVFVPSKSDASNW GVKTVSVKVLN*" gene complement(2092899..2093762) /gene="walL" /locus_tag="BSU_19210" /old_locus_tag="BSU19210" downshifts complement(2092912) /Source="Nicolas_upshifts" /id="D1056" /incds=0 /nref=227 /ntot=262 /MaxReadThrough="2.55593" /MaxDrop="7.59881" /score="23.8272007" /energy="-10.2" /TU="U1565" /idTUdmin="U1565" /TUdmin="-22" /isTUend="TRUE" downshifts 2092968 /Source="Nicolas_upshifts" /id="D1057" /incds=1 /nref=8 /ntot=28 /MaxReadThrough="6.14664" /MaxDrop="3.95582" /score="23.648858" /energy="-15.4" /TU="U1562" /idTUdmin="U1560" /TUdmin=682 /isTUend="FALSE" downshifts complement(2093000) /Source="Nicolas_upshifts" /id="D1058" /incds=1 /nref=10 /ntot=161 /MaxReadThrough="7.34609" /MaxDrop="3.8459" /score="23.8272007" /energy="-10.2" /TU="U1565" /idTUdmin="U1565" /TUdmin="-110" /isTUend="FALSE" S_feature 2093013..2093780 /Source="Nicolas_S_feature" /locus_tag="new_2093013_2093780" /HighExp="BT, S8, S6, Gly, S7, C30, G135, G/S, Fru, Pyr" /AntisenseName="yocH" /AntisenseCor="-0.12155468325348801" /AntisenseRegPval="-1.3" /CDS_PredictionProba="NA" /TUshortSig="SigK" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S733" promotor_-35 2093758..2093762 /Source="Nicolas_upshift_promotors" /id="U1564" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.999000999001" /psig="0.000999000999001" /xcortree=1239 /SigmaFactorBS="agtgcagcaactgccacaaaggacataatcgtcttcTTCATa agtaaatCCTCCCTTGTTAGCTttttattggcggctaacaggtgatatcgtaacacac g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2093771..2093785 /Source="Nicolas_upshift_promotors" /id="U1564" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.999000999001" /psig="0.000999000999001" /xcortree=1239 /SigmaFactorBS="agtgcagcaactgccacaaaggacataatcgtcttcTTCATa agtaaatCCTCCCTTGTTAGCTttttattggcggctaacaggtgatatcgtaacacac g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2093782 /Source="Nicolas_upshifts" /id="U1564" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.999000999001" /psig="0.000999000999001" /xcortree=1239 /SigmaFactorBS="agtgcagcaactgccacaaaggacataatcgtcttcTTCATa agtaaatCCTCCCTTGTTAGCTttttattggcggctaacaggtgatatcgtaacacac g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 complement(2093801..2093820) /Source="Nicolas_upshift_promotors" /id="U1565" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.762237762237762" /psig="0.999000999001" /xcortree=582 /SigmaFactorBS="gtaaaggaactgtaatctaaatcatatctttttgttATTGAT TtgacatttacgTGTGTTACGATATCACCTGTtagccgccaataaaaagctaacaagg g" /listShort="yocH" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2093814) /Source="Nicolas_upshifts" /id="U1565" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.762237762237762" /psig="0.999000999001" /xcortree=582 /SigmaFactorBS="gtaaaggaactgtaatctaaatcatatctttttgttATTGAT TtgacatttacgTGTGTTACGATATCACCTGTtagccgccaataaaaagctaacaagg g" /listShort="yocH" /GFF_Attribute="listLong" S_feature complement(2093816..2094009) /Source="Nicolas_S_feature" /locus_tag="new_2093816_2094009_c" /HighExp="LoTm, HiOs, S8, C30, S2, G135, G180, T5.0H, S7, BC" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="SigA" /TUlongPSig=1 /label="S734" promotor_-35 complement(2093832..2093838) /Source="Nicolas_upshift_promotors" /id="U1565" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.762237762237762" /psig="0.999000999001" /xcortree=582 /SigmaFactorBS="gtaaaggaactgtaatctaaatcatatctttttgttATTGAT TtgacatttacgTGTGTTACGATATCACCTGTtagccgccaataaaaagctaacaagg g" /listShort="yocH" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2094010..2095785) /gene="recQ" /locus_tag="BSU_19220" /old_locus_tag="BSU19220" /EC_number="3.6.1.12" /experiment="publication(s) with functional evidences, PMID:11886746, 16385024, 22200572, 25246477, 26001966" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11886746, 16385024, 22200572, 25246477, 26001966; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="ATP-dependent helicase" /protein_id="NP_389803.1" /db_xref="EnsemblGenomes-Gn:BSU19220" /db_xref="EnsemblGenomes-Tr:CAB13814" /db_xref="GOA:O34748" /db_xref="InterPro:IPR001650" /db_xref="InterPro:IPR002121" /db_xref="InterPro:IPR004589" /db_xref="InterPro:IPR006293" /db_xref="InterPro:IPR010997" /db_xref="InterPro:IPR011545" /db_xref="InterPro:IPR014001" /db_xref="InterPro:IPR018982" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR032284" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG13522" /db_xref="UniProtKB/Swiss-Prot:O34748" /translation="MLHRAQSLLAHYFGYEKFRSGQDEAIRLVTEARQNTACIMPTGG GKSICYQIPALMFEGTTIVISPLISLMKDQVDALEEAGINAAYINSTQSNQEIYERLN GLKEGAYKLFYITPERLTSIEFIRILQGIDVPLVAIDEAHCISQWGHDFRPSYRNIEI LFRELHDKPVIMALTATATPEVHDDICKQLHIQKENTVYTGFSRENLTFKVVKGENKD RFIDEYVQNNRHEAGIVYTATRKEADRIYERLKRNQVRAGRYHGGLADDVRKEQQERF LNDELQVMVATSAFGMGIDKSNIRFVLHAQIPKDMESYYQEAGRAGRDGLASECVLLF SPQDIMVQRFLIEQSEHEEKQKQDLKKLRQMVDYCHTEDCLQRFILMYFGEKEPDACG QCGNCTDTRAAHDVTREAQMVLSCIIRMKERFGKTMVAQVLAGSKNKKVLENGFSDLS TYGILKHQSVGEISDFIEFLISDDFIRMSDGTFPTLFVSSKGRNVLKGELSVARKEAL KAAAITENDELFERLRMVRKEIAAEQGVPPFVVFSDQTLKEMSGKQPVNDDELLSIKG VGEQKRAKYGRLFLQEIQAYARMTD*" gene complement(2094010..2095785) /gene="recQ" /locus_tag="BSU_19220" /old_locus_tag="BSU19220" S_feature complement(2095786..2095916) /Source="Nicolas_S_feature" /locus_tag="new_2095786_2095916_c" /HighExp="LoTm, G180, Cold, G135, G150, T5.0H, T4.0H, T3.30H, S2, LBGexp" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="SigA" /TUlongPSig=1 /label="S735" misc_RNA complement(2095909..2096111) /gene="ssrSA" /locus_tag="BSU_misc_RNA_32" /product="6Sa RNA" /experiment="publication(s) with functional evidences, PMID:11886746, 15793584, 15811922, 22333917, 25576829, 26873600" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11886746, 15793584, 15811922, 22333917, 25576829, 26873600; Product type n : RNA" gene complement(2095909..2096111) /gene="ssrSA" /locus_tag="BSU_misc_RNA_32" downshifts complement(2095961) /Source="Nicolas_upshifts" /id="D1059" /incds=0 /nref=34 /ntot=297 /MaxReadThrough="4.06142" /MaxDrop="7.97725" /score="26.8190437" /energy="-12.7" /TU="U1566" /idTUdmin="U1568" /TUdmin=163 /isTUend="FALSE" promotor_-10 complement(2096109..2096128) /Source="Nicolas_upshift_promotors" /id="U1566" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.554445554445554" /psig=1 /xcortree=418 /SigmaFactorBS="attcactggaaaaagtttttctaaacaattgttctgaccTCT TGATTaaaagcgcctgaTGGTGTACTATATTAAAGAAgctactttgtgcgtattgtta a" /listShort="NA, S735, yocI, S734" /listLong="yocH" /label="promotor_-10" upshifts complement(2096127) /Source="Nicolas_upshifts" /id="U1566" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.554445554445554" /psig=1 /xcortree=418 /SigmaFactorBS="attcactggaaaaagtttttctaaacaattgttctgaccTCT TGATTaaaagcgcctgaTGGTGTACTATATTAAAGAAgctactttgtgcgtattgtta a" /listShort="NA, S735, yocI, S734" /listLong="yocH" S_feature complement(2096129..2096321) /Source="Nicolas_S_feature" /locus_tag="new_2096129_2096321_c" /HighExp="dia5, Etha, dia15, Diami, S8, S7, C30, G180, G135, C90" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigB" /TUshortPSig="1, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S736" promotor_-35 complement(2096141..2096148) /Source="Nicolas_upshift_promotors" /id="U1566" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.554445554445554" /psig=1 /xcortree=418 /SigmaFactorBS="attcactggaaaaagtttttctaaacaattgttctgaccTCT TGATTaaaagcgcctgaTGGTGTACTATATTAAAGAAgctactttgtgcgtattgtta a" /listShort="NA, S735, yocI, S734" /listLong="yocH" /label="promotor_-35" CDS complement(2096350..2096976) /gene="azoJ" /locus_tag="BSU_19230" /old_locus_tag="BSU19230" /EC_number="1.7.-.-" /experiment="publication(s) with functional evidences, PMID:11886746, 18208493, 22200572" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11886746, 18208493, 22200572; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="FMN-dependent NADH-azoreductase" /protein_id="NP_389804.1" /db_xref="EnsemblGenomes-Gn:BSU19230" /db_xref="EnsemblGenomes-Tr:CAB13815" /db_xref="GOA:O35022" /db_xref="InterPro:IPR003680" /db_xref="InterPro:IPR023048" /db_xref="InterPro:IPR029039" /db_xref="SubtiList:BG13523" /db_xref="UniProtKB/Swiss-Prot:O35022" /translation="MSTVLFVKSSDRTAEEGVSTKLYEAFLAAYKENNPNDEVVELDL HKENLPYLGRDMINGTFKAGQGMEMTEDEKKQAAIADKYLNQFVKADKVVFAFPLWNF TVPAVLHTYVDYLSRAGVTFKYTQEGPVGLMGGKKVALLNARGGVYSEGPMAALEMSL NFMKTVLGFWGVQDLHTVVIEGHNAAPDQAQEIVEKGLQEAKDLAAKF*" gene complement(2096350..2096976) /gene="azoJ" /locus_tag="BSU_19230" /old_locus_tag="BSU19230" downshifts complement(2096366) /Source="Nicolas_upshifts" /id="D1060" /incds=0 /nref=68 /ntot=205 /MaxReadThrough="5.10353" /MaxDrop="5.66408" /score="1.15982687" /energy="-10.9" /TU="U1567,U1568" /idTUdmin="U1567" /TUdmin="-220" /isTUend="FALSE" promotor_-10 complement(2097010..2097029) /Source="Nicolas_upshift_promotors" /id="U1567" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.682317682317682" /psig=1 /xcortree=1846 /SigmaFactorBS="tttgaaaaaaaatctcatattcaaaataaagtgATTGACTTt acgtaaaaaagaAAGTAACATACTATTTGTAAgtaaatataaaaagtttaccgggagg a" /listShort="yocJ, S736" /listLong="NA, S735, yocI, S734, yocH" /label="promotor_-10" upshifts complement(2097023) /Source="Nicolas_upshifts" /id="U1567" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.682317682317682" /psig=1 /xcortree=1846 /SigmaFactorBS="tttgaaaaaaaatctcatattcaaaataaagtgATTGACTTt acgtaaaaaagaAAGTAACATACTATTTGTAAgtaaatataaaaagtttaccgggagg a" /listShort="yocJ, S736" /listLong="NA, S735, yocI, S734, yocH" promotor_-35 complement(2097043..2097050) /Source="Nicolas_upshift_promotors" /id="U1567" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.682317682317682" /psig=1 /xcortree=1846 /SigmaFactorBS="tttgaaaaaaaatctcatattcaaaataaagtgATTGACTTt acgtaaaaaagaAAGTAACATACTATTTGTAAgtaaatataaaaagtttaccgggagg a" /listShort="yocJ, S736" /listLong="NA, S735, yocI, S734, yocH" /label="promotor_-35" CDS complement(2097126..2097617) /gene="yocK" /locus_tag="BSU_19240" /old_locus_tag="BSU19240" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 10220166, 15496987, 15496987; Product type f: factor" /codon_start=1 /transl_table=11 /product="putative general stress protein" /protein_id="NP_389805.2" /db_xref="EnsemblGenomes-Gn:BSU19240" /db_xref="EnsemblGenomes-Tr:CAB13816" /db_xref="GOA:P80872" /db_xref="InterPro:IPR000962" /db_xref="InterPro:IPR020458" /db_xref="InterPro:IPR037187" /db_xref="SubtiList:BG13524" /db_xref="UniProtKB/Swiss-Prot:P80872" /translation="MALTKEQTQHLYHKLLDMQKELSGEKKETESMTEEVGELSNGVD NHMADHGTLVTDRMTDQTVKEIDRELLEEVNRALQKMKDGTYGVCEKTGQEIPYERLE AVPYARMTVEAQADVEDDLETDAPSYEREFHEQVKDLSNKETIDQKSSQTYEILDREQ DSK*" gene complement(2097126..2097617) /gene="yocK" /locus_tag="BSU_19240" /old_locus_tag="BSU19240" downshifts complement(2097135) /Source="Nicolas_upshifts" /id="D1061" /incds=0 /nref=5 /ntot=49 /MaxReadThrough="7.79466" /MaxDrop="4.30433" /score="1.15982687" /energy="-10.9" /TU="U1568,U1573" /idTUdmin="U1571" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(2097629..2097647) /Source="Nicolas_upshift_promotors" /id="U1568" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=238 /SigmaFactorBS="aaggcagtagctcatctttccatcgatgtttccaTGTTTGAc agaaggcaaaacGGGAAACAGGATAGAAAGGagaggatatacatggcactgacaaaag a" /listShort="yocK, yocJ, S736" /listLong="NA" /label="promotor_-10" upshifts complement(2097641) /Source="Nicolas_upshifts" /id="U1568" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=238 /SigmaFactorBS="aaggcagtagctcatctttccatcgatgtttccaTGTTTGAc agaaggcaaaacGGGAAACAGGATAGAAAGGagaggatatacatggcactgacaaaag a" /listShort="yocK, yocJ, S736" /listLong="NA" promotor_-35 complement(2097661..2097667) /Source="Nicolas_upshift_promotors" /id="U1568" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=238 /SigmaFactorBS="aaggcagtagctcatctttccatcgatgtttccaTGTTTGAc agaaggcaaaacGGGAAACAGGATAGAAAGGagaggatatacatggcactgacaaaag a" /listShort="yocK, yocJ, S736" /listLong="NA" /label="promotor_-35" CDS complement(2097692..2098024) /gene="yocL" /locus_tag="BSU_19250" /old_locus_tag="BSU19250" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 21926231" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_389806.1" /db_xref="EnsemblGenomes-Gn:BSU19250" /db_xref="EnsemblGenomes-Tr:CAB13817" /db_xref="SubtiList:BG13525" /db_xref="UniProtKB/Swiss-Prot:O34976" /translation="MKKMFRSLIRHCLKPELDKLRECEERLSVIEKQKQSSKQESEET YIHIETLNVEKVDYHLEFGELTIDELSGRLNIGATYYIPPEEKDKKCQRKPEAPSTPA VTIRSKRQ*" gene complement(2097692..2098024) /gene="yocL" /locus_tag="BSU_19250" /old_locus_tag="BSU19250" S_feature complement(2098025..2098315) /Source="Nicolas_S_feature" /locus_tag="new_2098025_2098315_c" /HighExp="Salt, Cold, S3, S8, S4, S7, T5.0H, T3.30H, S6, T4.0H" /AntisenseName="yoyB" /AntisenseCor="0.489341986454357" /AntisenseRegPval="-16.899999999999999" /CDS_PredictionProba="NA" /TUshortSig="SigEF, SigA, SigWXY" /TUshortPSig="0.698, 0.799, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S737" promotor_-35 2098040..2098045 /Source="Nicolas_upshift_promotors" /id="U1569" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.877122877122877" /psig="0.877122877122877" /xcortree=1142 /SigmaFactorBS="agcgaccggaacatttttttcatgacatcacgacccttTGCA TActcctctttcgtctACATATATAATGAGGTATAtcccatagaaaggagaggttttc a" /listShort="yoyB, S738" /listLong="yozN, yocN" /label="promotor_-35" promotor_-10 2098060..2098078 /Source="Nicolas_upshift_promotors" /id="U1569" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.877122877122877" /psig="0.877122877122877" /xcortree=1142 /SigmaFactorBS="agcgaccggaacatttttttcatgacatcacgacccttTGCA TActcctctttcgtctACATATATAATGAGGTATAtcccatagaaaggagaggttttc a" /listShort="yoyB, S738" /listLong="yozN, yocN" /label="promotor_-10" upshifts 2098062 /Source="Nicolas_upshifts" /id="U1569" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.877122877122877" /psig="0.877122877122877" /xcortree=1142 /SigmaFactorBS="agcgaccggaacatttttttcatgacatcacgacccttTGCA TActcctctttcgtctACATATATAATGAGGTATAtcccatagaaaggagaggttttc a" /listShort="yoyB, S738" /listLong="yozN, yocN" CDS 2098102..2098329 /gene="yoyB" /locus_tag="BSU_19259" /old_locus_tag="BSU19259" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 19383706, 20709900" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="YP_003097740.1" /db_xref="EnsemblGenomes-Gn:BSU19259" /db_xref="EnsemblGenomes-Tr:CAX52637" /db_xref="UniProtKB/Swiss-Prot:C0H429" /translation="MLPTNINISHLKTNSIGTGSSLTFGSAELRNRCSAIKRNNGFGE QNADGIVMVIPIESIDDRDVSDALSMKINHQ*" gene 2098102..2098329 /gene="yoyB" /locus_tag="BSU_19259" /old_locus_tag="BSU19259" CDS complement(2098316..2098792) /gene="yocM" /locus_tag="BSU_19260" /old_locus_tag="BSU19260" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 11150673, 23155385; Product type f: factor" /codon_start=1 /transl_table=11 /product="putative chaperone" /protein_id="NP_389808.1" /db_xref="EnsemblGenomes-Gn:BSU19260" /db_xref="EnsemblGenomes-Tr:CAB13818" /db_xref="InterPro:IPR002068" /db_xref="InterPro:IPR008978" /db_xref="InterPro:IPR031107" /db_xref="SubtiList:BG13526" /db_xref="UniProtKB/Swiss-Prot:O34321" /translation="MDFEKMKQWMEFAQQMYGGDFWKQVFDEDQKTPFMTNGQSPFPF AQQDQRGKGDASFPSMDIVDTVAEVQFLIYLPGYRKQDVHILSYGDYLVVKGQRFSYF NEQDFRQKEGKYGSFEKKIPLSDHLHGKMNAIFKDGILYITIQKDEGQAKTIVIDD*" gene complement(2098316..2098792) /gene="yocM" /locus_tag="BSU_19260" /old_locus_tag="BSU19260" S_feature 2098330..2098837 /Source="Nicolas_S_feature" /locus_tag="new_2098330_2098837" /HighExp="S6, S5, S8, S7, S4, B36, BT, S3, T5.0H, LoTm" /AntisenseName="yocM" /AntisenseCor="0.54530996552252997" /AntisenseRegPval="-21.5" /CDS_PredictionProba="NA" /TUshortSig="SigEF" /TUshortPSig="0.877" /TUlongSig="NA" /TUlongPSig="NA" /label="S738" S_feature complement(2098793..2098895) /Source="Nicolas_S_feature" /locus_tag="new_2098793_2098895_c" /HighExp="Cold, Salt, S8, T5.0H, S3, T-0.40H, T0.0H, S4, T4.0H, S6" /AntisenseName="yozN" /AntisenseCor="0.471443110130365" /AntisenseRegPval="-15.6" /CDS_PredictionProba="NA" /TUshortSig="SigEF, SigA, SigWXY" /TUshortPSig="0.698, 0.799, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S739" promotor_-35 2098810..2098815 /Source="Nicolas_upshift_promotors" /id="U1570" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1089 /SigmaFactorBS="ttttcgaaatccatttgaagccccctgtcttAACATActtta taaccgccaGCATACAACTATAGAAAGGaggtttgcctgtggttcaaccaactccgta t" /listShort="yozN, yocN" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2098830..2098848 /Source="Nicolas_upshift_promotors" /id="U1570" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1089 /SigmaFactorBS="ttttcgaaatccatttgaagccccctgtcttAACATActtta taaccgccaGCATACAACTATAGAAAGGaggtttgcctgtggttcaaccaactccgta t" /listShort="yozN, yocN" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2098839 /Source="Nicolas_upshifts" /id="U1570" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1089 /SigmaFactorBS="ttttcgaaatccatttgaagccccctgtcttAACATActtta taaccgccaGCATACAACTATAGAAAGGaggtttgcctgtggttcaaccaactccgta t" /listShort="yozN, yocN" /GFF_Attribute="listLong" CDS 2098859..2099122 /gene="yozN" /locus_tag="BSU_19270" /old_locus_tag="BSU19270" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 20709900" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function (mother cell in sporulation)" /protein_id="NP_389809.1" /db_xref="EnsemblGenomes-Gn:BSU19270" /db_xref="EnsemblGenomes-Tr:CAB13819" /db_xref="SubtiList:BG13761" /db_xref="UniProtKB/Swiss-Prot:O31846" /translation="MVQPTPYININIFMLKINSFENASAVNVGQNLLAEWQNSDKKNQ GYGQNFGDASGFMGTRSHVDDRDQIDSPASFESEAVNSSIKRK*" gene 2098859..2099122 /gene="yozN" /locus_tag="BSU_19270" /old_locus_tag="BSU19270" promotor_-10 complement(2098875..2098894) /Source="Nicolas_upshift_promotors" /id="U1571" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.698301698301698" /psig="0.698301698301698" /xcortree=1042 /SigmaFactorBS="ataaattttgtcctacgttaaccgctgaagcattttcaaagg aATTAAttttcagcatgaaAATATTAATATTGATATACGgagttggttgaaccacagg c" /listShort="S739, yocM, S737, yocL, yocK" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2098895) /Source="Nicolas_upshifts" /id="U1571" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.698301698301698" /psig="0.698301698301698" /xcortree=1042 /SigmaFactorBS="ataaattttgtcctacgttaaccgctgaagcattttcaaagg aATTAAttttcagcatgaaAATATTAATATTGATATACGgagttggttgaaccacagg c" /listShort="S739, yocM, S737, yocL, yocK" /GFF_Attribute="listLong" S_feature complement(2098897..2099422) /Source="Nicolas_S_feature" /locus_tag="new_2098897_2099422_c" /HighExp="Salt, Cold, T-0.40H, T0.0H, T0.30H, T-1.10H, T-1.40H, T3.30H, T2.0H, S0" /AntisenseName="yocN" /AntisenseCor="-0.51964820699949898" /AntisenseRegPval="-19.3" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigWXY" /TUshortPSig="0.799, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S740" promotor_-35 complement(2098908..2098912) /Source="Nicolas_upshift_promotors" /id="U1571" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.698301698301698" /psig="0.698301698301698" /xcortree=1042 /SigmaFactorBS="ataaattttgtcctacgttaaccgctgaagcattttcaaagg aATTAAttttcagcatgaaAATATTAATATTGATATACGgagttggttgaaccacagg c" /listShort="S739, yocM, S737, yocL, yocK" /GFF_Attribute="listLong" /label="promotor_-35" CDS 2099127..2099360 /gene="yocN" /locus_tag="BSU_19280" /old_locus_tag="BSU19280" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 20709900" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function (sporulation-related)" /protein_id="NP_389810.1" /db_xref="EnsemblGenomes-Gn:BSU19280" /db_xref="EnsemblGenomes-Tr:CAB13820" /db_xref="SubtiList:BG13527" /db_xref="UniProtKB/Swiss-Prot:O34855" /translation="MFFSPSVVNVGGFKINTMDRGSSLTLGPYQQVDYFLSAKINQGF GEENGDFTPLVVPISNVLDADLVDSNSAKNSVV*" gene 2099127..2099360 /gene="yocN" /locus_tag="BSU_19280" /old_locus_tag="BSU19280" downshifts 2099347 /Source="Nicolas_upshifts" /id="D1062" /incds=0 /nref=62 /ntot=90 /MaxReadThrough="2.0117" /MaxDrop="7.59451" /score="5.68120132" /energy="-10.9" /TU="NA" /idTUdmin="U1570" /TUdmin=0 /isTUend="TRUE" CDS complement(2099446..2099790) /gene="yozO" /locus_tag="BSU_19290" /old_locus_tag="BSU19290" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 23155385" /codon_start=1 /transl_table=11 /product="conserved hypothetical phage protein" /protein_id="NP_389811.1" /db_xref="EnsemblGenomes-Gn:BSU19290" /db_xref="EnsemblGenomes-Tr:CAB13821" /db_xref="InterPro:IPR011993" /db_xref="InterPro:IPR012544" /db_xref="InterPro:IPR037063" /db_xref="SubtiList:BG13762" /db_xref="UniProtKB/Swiss-Prot:O31847" /translation="MGIFSVSRSTDAKKLEALLVEGERIESIYKLRVDQICFTNKRII FFDNKMFSKKKVRVFLPYKTIESFAIQEAGMFDPDTGLLLMTRSKTFELEFAKDTDLS EVQAVLTKHLCS*" gene complement(2099446..2099790) /gene="yozO" /locus_tag="BSU_19290" /old_locus_tag="BSU19290" downshifts complement(2099467) /Source="Nicolas_upshifts" /id="D1063" /incds=0 /nref=61 /ntot=217 /MaxReadThrough="4.58642" /MaxDrop="4.1868" /score="12.6520239" /energy="-9.6" /TU="U1572,U1573" /idTUdmin="U1574" /TUdmin=616 /isTUend="FALSE" S_feature complement(2099791..2099863) /Source="Nicolas_S_feature" /locus_tag="new_2099791_2099863_c" /HighExp="T0.30H, T0.0H, T1.0H, T-0.40H, T1.30H, T-1.10H, Salt, T2.0H, T-1.40H, T2.30H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigWXY" /TUshortPSig="0.799, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S741" promotor_-10 complement(2099859..2099878) /Source="Nicolas_upshift_promotors" /id="U1572" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.421578421578422" /psig="0.7992007992008" /xcortree=1714 /SigmaFactorBS="aatttgaaaaatgtaatctgttcgtaATGGTTtaaatgtctt ctaTGTCGTATTCTTATATAGGGataaaggacttatttttatgtagtgaatgataaaa c" /listShort="S741, yozO, S740, S739, yocM, S737, yocL, yocK" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2099863) /Source="Nicolas_upshifts" /id="U1572" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.421578421578422" /psig="0.7992007992008" /xcortree=1714 /SigmaFactorBS="aatttgaaaaatgtaatctgttcgtaATGGTTtaaatgtctt ctaTGTCGTATTCTTATATAGGGataaaggacttatttttatgtagtgaatgataaaa c" /listShort="S741, yozO, S740, S739, yocM, S737, yocL, yocK" /GFF_Attribute="listLong" S_feature complement(2099865..2099968) /Source="Nicolas_S_feature" /locus_tag="new_2099865_2099968_c" /HighExp="T0.30H, T0.0H, T-0.40H, T1.0H, T1.30H, Salt, T-1.10H, T2.0H, T-1.40H, T2.30H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigWXY" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S742" promotor_-35 complement(2099892..2099897) /Source="Nicolas_upshift_promotors" /id="U1572" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.421578421578422" /psig="0.7992007992008" /xcortree=1714 /SigmaFactorBS="aatttgaaaaatgtaatctgttcgtaATGGTTtaaatgtctt ctaTGTCGTATTCTTATATAGGGataaaggacttatttttatgtagtgaatgataaaa c" /listShort="S741, yozO, S740, S739, yocM, S737, yocL, yocK" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(2099955..2099970) /Source="Nicolas_upshift_promotors" /id="U1573" /multdbtbs="SigW" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1697 /SigmaFactorBS="taaaaaccacttttttataaaaacattgctgaatatTGAAAC TTTTttctctatatgtGCGTATTACTTGATGAcaacagcttaaaagccaaaaaacaaa t" /listShort="S742, S741, yozO, S740, S739, yocM, S737, yocL, yocK, yocJ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2099968) /Source="Nicolas_upshifts" /id="U1573" /multdbtbs="SigW" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1697 /SigmaFactorBS="taaaaaccacttttttataaaaacattgctgaatatTGAAAC TTTTttctctatatgtGCGTATTACTTGATGAcaacagcttaaaagccaaaaaacaaa t" /listShort="S742, S741, yozO, S740, S739, yocM, S737, yocL, yocK, yocJ" /GFF_Attribute="listLong" promotor_-35 complement(2099983..2099992) /Source="Nicolas_upshift_promotors" /id="U1573" /multdbtbs="SigW" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1697 /SigmaFactorBS="taaaaaccacttttttataaaaacattgctgaatatTGAAAC TTTTttctctatatgtGCGTATTACTTGATGAcaacagcttaaaagccaaaaaacaaa t" /listShort="S742, S741, yozO, S740, S739, yocM, S737, yocL, yocK, yocJ" /GFF_Attribute="listLong" /label="promotor_-35" downshifts complement(2100111) /Source="Nicolas_upshifts" /id="D1064" /incds=0 /nref=117 /ntot=269 /MaxReadThrough="5.5406" /MaxDrop="6.72115" /score="36.7697843" /energy="-10.7" /TU="U1574" /idTUdmin="U1576" /TUdmin="-6" /isTUend="TRUE" CDS complement(2100147..2100350) /gene="yozC" /locus_tag="BSU_19300" /old_locus_tag="BSU19300" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_389812.1" /db_xref="EnsemblGenomes-Gn:BSU19300" /db_xref="EnsemblGenomes-Tr:CAB13822" /db_xref="SubtiList:BG13750" /db_xref="UniProtKB/Swiss-Prot:O31848" /translation="MIHKNWLEKETIKKVKCVQTNAKKYIVNRVLTPGKEYEVKNETE EFLFVVDNTNKVGGYYKEYFEEM*" gene complement(2100147..2100350) /gene="yozC" /locus_tag="BSU_19300" /old_locus_tag="BSU19300" promotor_-10 complement(2100371..2100390) /Source="Nicolas_upshift_promotors" /id="U1574" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.938061938061938" /psig=1 /xcortree=2988 /SigmaFactorBS="ataatagaaatcaaggcaaaatcaatgaataaccgaTATTGC AAtttacaaaagaaaaaAGCTACAATAAGCTTATAGAtaagaaaaggagatttcatca t" /listShort="yozC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2100389) /Source="Nicolas_upshifts" /id="U1574" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.938061938061938" /psig=1 /xcortree=2988 /SigmaFactorBS="ataatagaaatcaaggcaaaatcaatgaataaccgaTATTGC AAtttacaaaagaaaaaAGCTACAATAAGCTTATAGAtaagaaaaggagatttcatca t" /listShort="yozC" /GFF_Attribute="listLong" S_feature complement(2100391..2100457) /Source="Nicolas_S_feature" /locus_tag="new_2100391_2100457_c" /HighExp="S7, S8, S6, S5, C30, S4, T4.0H, B60, BC, B36" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="Sig-" /TUshortPSig="0.461" /TUlongSig="NA" /TUlongPSig="NA" /label="S743" promotor_-35 complement(2100406..2100413) /Source="Nicolas_upshift_promotors" /id="U1574" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.938061938061938" /psig=1 /xcortree=2988 /SigmaFactorBS="ataatagaaatcaaggcaaaatcaatgaataaccgaTATTGC AAtttacaaaagaaaaaAGCTACAATAAGCTTATAGAtaagaaaaggagatttcatca t" /listShort="yozC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 2100423..2100430 /Source="Nicolas_upshift_promotors" /id="U1575" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.59040959040959" /psig="0.96103896103896" /xcortree=509 /SigmaFactorBS="attgtagcttttttcttttgtaaattgcaatatcggttattC ATTGATTttgccttgatttcTATTATAGAATGTTTGTATAcgcttacgtttgaagcaa c" /listShort="S744, dhaS, sqhC" /listLong="sodF" /label="promotor_-35" upshifts 2100442 /Source="Nicolas_upshifts" /id="U1575" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.59040959040959" /psig="0.96103896103896" /xcortree=509 /SigmaFactorBS="attgtagcttttttcttttgtaaattgcaatatcggttattC ATTGATTttgccttgatttcTATTATAGAATGTTTGTATAcgcttacgtttgaagcaa c" /listShort="S744, dhaS, sqhC" /listLong="sodF" misc_feature complement(2100444..2100456) /Source="Nicolas_upshift_promotors" /id="U1576" /multdbtbs="-" /comp="M5" /sig="Sig-" /pcomp="0.406593406593407" /psig="0.460539460539461" /xcortree=1224 /SigmaFactorBS="atagcacattgattcctggattgaatagcagaaataagctgt gatagttgcttcaaacgtaagcgtatacaaACATTCTATAATAgaaatcaaggcaaaa t" /listShort="S743, yozC" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" promotor_-10 2100444..2100463 /Source="Nicolas_upshift_promotors" /id="U1575" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.59040959040959" /psig="0.96103896103896" /xcortree=509 /SigmaFactorBS="attgtagcttttttcttttgtaaattgcaatatcggttattC ATTGATTttgccttgatttcTATTATAGAATGTTTGTATAcgcttacgtttgaagcaa c" /listShort="S744, dhaS, sqhC" /listLong="sodF" /label="promotor_-10" S_feature 2100447..2100579 /Source="Nicolas_S_feature" /locus_tag="new_2100447_2100579" /HighExp="BC, M0t90, M9-stat, S2, T2.30H, Sw, Lbstat, M40t90, T4.0H, T3.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.961" /TUlongSig="NA" /TUlongPSig="NA" /label="S744" upshifts complement(2100468) /Source="Nicolas_upshifts" /id="U1576" /multdbtbs="-" /comp="M5" /sig="Sig-" /pcomp="0.406593406593407" /psig="0.460539460539461" /xcortree=1224 /SigmaFactorBS="atagcacattgattcctggattgaatagcagaaataagctgt gatagttgcttcaaacgtaagcgtatacaaACATTCTATAATAgaaatcaaggcaaaa t" /listShort="S743, yozC" /GFF_Attribute="listLong" CDS 2100580..2102067 /gene="dhaS" /locus_tag="BSU_19310" /old_locus_tag="BSU19310" /EC_number="1.2.1.3" /function="16.11: Scavenge (Catabolism)" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:17555270, 23874669, 25409630, 26337367, 27797724" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 17555270, 23874669, 25409630, 26337367, 27797724; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="3-hydroxypropionaldehyde dehydrogenase" /protein_id="NP_389813.1" /db_xref="EnsemblGenomes-Gn:BSU19310" /db_xref="EnsemblGenomes-Tr:CAB13823" /db_xref="GOA:O34660" /db_xref="InterPro:IPR012394" /db_xref="InterPro:IPR015590" /db_xref="InterPro:IPR016161" /db_xref="InterPro:IPR016162" /db_xref="InterPro:IPR029510" /db_xref="SubtiList:BG12582" /db_xref="UniProtKB/Swiss-Prot:O34660" /translation="MSSLTMQVTKRLETFLQGTKKLYIDGKFVPSASGATFDTPNPAT GETLMTLYEAQAADVDKAVKAARKAFDQGEWRTMSPASRSRLMYKLADLMEEHKTELA QLETLDNGKPINETTNGDIPLAIEHMRYYAGWCTKITGQTIPVSGAYFNYTRHEPVGV VGQIIPWNFPLLMAMWKMGAALATGCTIVLKPAEQTPLSALYLAELIDQAGFPAGVIN IIPGFGEDAGEALTNHEAVDKIAFTGSTEIGKKIMSTAAKSIKRVTLELGGKSPNILL PDANLKKAIPGALNGVMFNQGQVCCAGSRVFIHKDQYDEVVDEMASYAESLRQGAGLH KDTQIGPLVSKEQHERVLSYIQKGKDEGAKAVTGGSCPFEAGYFVAPTVFANVEDEMT IAKEEIFGPVLTAIPYETVDEVIERANHSEYGLAAGLWTENVKQAHYIADRLQAGTVW VNCYNVFDAASPFGGYKQSGLGREMGSYALDNYTEVKSVWVNLED*" gene 2100580..2102067 /gene="dhaS" /locus_tag="BSU_19310" /old_locus_tag="BSU19310" promotor_-10 complement(2101023..2101040) /Source="Nicolas_upshift_promotors" /id="U1577" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.526473526473527" /psig="0.526473526473527" /xcortree=656 /SigmaFactorBS="cgggaaattccatggaatgatctggccgACGACACCGacagg ctcatgaCGCGTATAATTAAAATAAgcgccggaaaccggaatcgtctgtcctgttatt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2101029) /Source="Nicolas_upshifts" /id="U1577" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.526473526473527" /psig="0.526473526473527" /xcortree=656 /SigmaFactorBS="cgggaaattccatggaatgatctggccgACGACACCGacagg ctcatgaCGCGTATAATTAAAATAAgcgccggaaaccggaatcgtctgtcctgttatt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(2101053..2101061) /Source="Nicolas_upshift_promotors" /id="U1577" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.526473526473527" /psig="0.526473526473527" /xcortree=656 /SigmaFactorBS="cgggaaattccatggaatgatctggccgACGACACCGacagg ctcatgaCGCGTATAATTAAAATAAgcgccggaaaccggaatcgtctgtcctgttatt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 2102053 /Source="Nicolas_upshifts" /id="D1065" /incds=0 /nref=163 /ntot=260 /MaxReadThrough="3.66831" /MaxDrop="7.01026" /score="24.6079855" /energy="-7.1" /TU="U1575" /idTUdmin="U1575" /TUdmin="-1144" /isTUend="FALSE" promotor_-35 2102115..2102120 /Source="Nicolas_upshift_promotors" /id="U1578" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.988011988011988" /psig="0.988011988011988" /xcortree=1130 /SigmaFactorBS="aaaactgctgcctgccagcagtttttttctttctGTAATGgc agtaaaagacgctGAATATATATGCTTCTGAAggagttgagcgtgatgggcacacttc a" /listShort="sqhC, sodF, S745" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2102136..2102154 /Source="Nicolas_upshift_promotors" /id="U1578" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.988011988011988" /psig="0.988011988011988" /xcortree=1130 /SigmaFactorBS="aaaactgctgcctgccagcagtttttttctttctGTAATGgc agtaaaagacgctGAATATATATGCTTCTGAAggagttgagcgtgatgggcacacttc a" /listShort="sqhC, sodF, S745" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2102141 /Source="Nicolas_upshifts" /id="U1578" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.988011988011988" /psig="0.988011988011988" /xcortree=1130 /SigmaFactorBS="aaaactgctgcctgccagcagtttttttctttctGTAATGgc agtaaaagacgctGAATATATATGCTTCTGAAggagttgagcgtgatgggcacacttc a" /listShort="sqhC, sodF, S745" /GFF_Attribute="listLong" CDS 2102168..2104066 /gene="sqhC" /locus_tag="BSU_19320" /old_locus_tag="BSU19320" /EC_number="4.2.1.137" /EC_number="5.4.99.17" /function="16.13: Shape" /function="16.8: Protect" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:2253626, 18436644, 18630919, 21627333" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 2253626, 18436644, 18630919, 21627333; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="squalene-hopene cyclase, sporulenol synthase (spore protection)" /protein_id="NP_389814.2" /db_xref="EnsemblGenomes-Gn:BSU19320" /db_xref="EnsemblGenomes-Tr:CAB13824" /db_xref="GOA:Q796C3" /db_xref="InterPro:IPR008930" /db_xref="InterPro:IPR018333" /db_xref="InterPro:IPR032696" /db_xref="InterPro:IPR032697" /db_xref="SubtiList:BG12679" /db_xref="UniProtKB/Swiss-Prot:Q796C3" /translation="MGTLQEKVRRFQKKTITELRDRQNADGSWTFCFEGPIMTNSFFI LLLTSLDEGENEKELISSLAAGIHAKQQPDGTFINYPDETRGNLTATVQGYVGMLASG CFHRTEPHMKKAEQFIISHGGLRHVHFMTKWMLAANGLYPWPALYLPLSLMALPPTLP IHFYQFSSYARIHFAPMAVTLNQRFVLINRNISSLHHLDPHMTKNPFTWLRSDAFEER DLTSILLHWKRVFHAPFAFQQLGLQTAKTYMLDRIEKDGTLYSYASATIYMVYSLLSL GVSRYSPIIRRAITGIKSLVTKCNGIPYLENSTSTVWDTALISYALQKNGVTETDGSV TKAADFLLERQHTKIADWSVKNPNSVPGGWGFSNINTNNPDCDDTTAVLKAIPRNHSP AAWERGVSWLLSMQNNDGGFSAFEKNVNHPLIRLLPLESAEDAAVDPSTADLTGRVLH FLGEKVGFTEKHQHIQRAVKWLFEHQEQNGSWYGRWGVCYIYGTWAALTGMHACGVDR KHPGIQKALRWLKSIQNDDGSWGESCKSAEIKTYVPLHRGTIVQTAWALDALLTYENS EHPSVVKGMQYLTDSSSHSADSLAYPAGIGLPKQFYIRYHSYPYVFSLLAVGKYLDSI EKETANET*" gene 2102168..2104066 /gene="sqhC" /locus_tag="BSU_19320" /old_locus_tag="BSU19320" promotor_-10 complement(2103111..2103130) /Source="Nicolas_upshift_promotors" /id="U1579" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1383 /SigmaFactorBS="ctgcttttgtaacagagccatccgttTCGGTCACACcatttt tttgaagGGCATAGCTTATTAAAGCTGtatcccaaacagttgaagtagagttttccag a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2103119) /Source="Nicolas_upshifts" /id="U1579" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1383 /SigmaFactorBS="ctgcttttgtaacagagccatccgttTCGGTCACACcatttt tttgaagGGCATAGCTTATTAAAGCTGtatcccaaacagttgaagtagagttttccag a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(2103144..2103153) /Source="Nicolas_upshift_promotors" /id="U1579" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1383 /SigmaFactorBS="ctgcttttgtaacagagccatccgttTCGGTCACACcatttt tttgaagGGCATAGCTTATTAAAGCTGtatcccaaacagttgaagtagagttttccag a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" CDS 2104056..2104901 /gene="sodF" /locus_tag="BSU_19330" /old_locus_tag="BSU19330" /EC_number="1.15.1.1" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2b: Function from indirect experimental evidences (e.g. phenotypes); PubMedId: 17114254, 20233928; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="superoxide dismutase (Fe2+-dependent)" /protein_id="NP_389815.1" /db_xref="EnsemblGenomes-Gn:BSU19330" /db_xref="EnsemblGenomes-Tr:CAB13825" /db_xref="GOA:O35023" /db_xref="InterPro:IPR001189" /db_xref="InterPro:IPR019831" /db_xref="InterPro:IPR019832" /db_xref="InterPro:IPR019833" /db_xref="InterPro:IPR036314" /db_xref="InterPro:IPR036324" /db_xref="SubtiList:BG12676" /db_xref="UniProtKB/Swiss-Prot:O35023" /translation="MKRESYQAEMFNWCEALKDQIQKRGQLDQFEDQIDKMIEALEDD QTTEEDWYKQAAALYRDITESDDTSERRAYVPIGKHVLPKLPYKYSALEPYISRDIMI LHHTKHHQSYVDGLNKAESELKKARATKNYDLITHWERELAFHGAGHYLHSIFWFSMH PNGKRRPTGALFQMIDLSFGSYSAFKEHFTQASKKVEGVGWAILVWAPRSGRLEILTA EKHQLFSQWDVIPLLPLDVWEHAYYLQYKNDRASYVDHWWNVVDWREAEKRFEQAKEV VWKLY*" gene 2104056..2104901 /gene="sodF" /locus_tag="BSU_19330" /old_locus_tag="BSU19330" S_feature 2104902..2106408 /Source="Nicolas_S_feature" /locus_tag="new_2104902_2106408" /HighExp="S5, S6, S4, S8, S3, S7, T5.0H, B36, BT, T4.0H" /AntisenseName="yocR" /AntisenseCor="-0.62866346519731298" /AntisenseRegPval="-30.3" /CDS_PredictionProba="NA" /TUshortSig="SigEF" /TUshortPSig="0.988" /TUlongSig="NA" /TUlongPSig="NA" /label="S745" CDS complement(2104934..2106271) /gene="yocR" /locus_tag="BSU_19340" /old_locus_tag="BSU19340" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406, 17114254, 27766092; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative sodium-dependent transporter" /protein_id="NP_389816.1" /db_xref="EnsemblGenomes-Gn:BSU19340" /db_xref="EnsemblGenomes-Tr:CAB13826" /db_xref="GOA:O34383" /db_xref="InterPro:IPR000175" /db_xref="SubtiList:BG13528" /db_xref="UniProtKB/Swiss-Prot:O34383" /translation="MKEANQWSSKLGFILAAAGSAIGLGAIWKFPYVAGTSGGGAFLL IFILFTVLIGLPLLLGEFIIGRRTQKDAVQSYKTLAPGTKWHWIGYLGMVTCFILLSF YSVVGGWILIYIIKGFTGGLSQTSGFDTIFASTISNPYLAVGGQLLFMVVTILVVAKG VSSGIEKASQVLMPALFLLFIILMVRSVTLDGAMEGIKFFLMPDLTAIDANTILYAMG QSFFLLSVGVSVMVTYSAYLEKQENLVQSAVSVTVMNMLVAVMAGIAIFPAVFSFGLK PDQGPVLLFNVLPTVFNQMPFGIIFLLAFLLLFLFAALTSAFSMLEILVAVLSKGDIN KRKRFAWLGGIAIFIVGVPSALSYGVLSDVTIFHLSIFDAADYLVSNILMPLGALLIS IFVPLKIPKQDLFDELKSGSNLKRKWFAVWLLLIRYLSPVAIIIVFLHVIGIF*" gene complement(2104934..2106271) /gene="yocR" /locus_tag="BSU_19340" /old_locus_tag="BSU19340" downshifts complement(2104945) /Source="Nicolas_upshifts" /id="D1066" /incds=0 /nref=1 /ntot=50 /MaxReadThrough="0.83968" /MaxDrop="2.44824" /score="27.8372036" /energy="-11.1" /TU="NA" /idTUdmin="U1580" /TUdmin=154 /isTUend="FALSE" promotor_-10 complement(2106299..2106318) /Source="Nicolas_upshift_promotors" /id="U1580" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.993006993006993" /psig=1 /xcortree=2402 /SigmaFactorBS="tctatagatatatgatgtaaactaattaaaatgtTCTTGACT atataggaagatatTCTTACAATGAACCTTTATAatggttagatcaaataggagtgat a" /listShort="yocR" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2106314) /Source="Nicolas_upshifts" /id="U1580" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.993006993006993" /psig=1 /xcortree=2402 /SigmaFactorBS="tctatagatatatgatgtaaactaattaaaatgtTCTTGACT atataggaagatatTCTTACAATGAACCTTTATAatggttagatcaaataggagtgat a" /listShort="yocR" /GFF_Attribute="listLong" S_feature complement(2106316..2107474) /Source="Nicolas_S_feature" /locus_tag="new_2106316_2107474_c" /HighExp="M9-stat, T1.30H, B60, T1.0H, T2.0H, T0.30H, T2.30H, T3.0H, T3.30H, Etha" /AntisenseName="yocS" /AntisenseCor="-6.3575129468026695E-2" /AntisenseRegPval="-0.5" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="SigA" /TUlongPSig=1 /label="S746" promotor_-35 complement(2106333..2106340) /Source="Nicolas_upshift_promotors" /id="U1580" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.993006993006993" /psig=1 /xcortree=2402 /SigmaFactorBS="tctatagatatatgatgtaaactaattaaaatgtTCTTGACT atataggaagatatTCTTACAATGAACCTTTATAatggttagatcaaataggagtgat a" /listShort="yocR" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 2106392..2106395 /Source="Nicolas_upshift_promotors" /id="U1581" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.611388611388611" /psig=1 /xcortree=2909 /SigmaFactorBS="ttagtttacatcatatatctatagacatctgccaaaaactaa TATTgaattattcagaaaATTATTTATAATAAGAGAATgttatgaaatttgtaagaat t" /listShort="yocS" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2106410..2106429 /Source="Nicolas_upshift_promotors" /id="U1581" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.611388611388611" /psig=1 /xcortree=2909 /SigmaFactorBS="ttagtttacatcatatatctatagacatctgccaaaaactaa TATTgaattattcagaaaATTATTTATAATAAGAGAATgttatgaaatttgtaagaat t" /listShort="yocS" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2106410 /Source="Nicolas_upshifts" /id="U1581" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.611388611388611" /psig=1 /xcortree=2909 /SigmaFactorBS="ttagtttacatcatatatctatagacatctgccaaaaactaa TATTgaattattcagaaaATTATTTATAATAAGAGAATgttatgaaatttgtaagaat t" /listShort="yocS" /GFF_Attribute="listLong" CDS 2106490..2107455 /gene="yocS" /locus_tag="BSU_19350" /old_locus_tag="BSU19350" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406, 27766092; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative sodium-dependent symporter" /protein_id="NP_389817.1" /db_xref="EnsemblGenomes-Gn:BSU19350" /db_xref="EnsemblGenomes-Tr:CAB13827" /db_xref="GOA:O34524" /db_xref="InterPro:IPR002657" /db_xref="InterPro:IPR004710" /db_xref="SubtiList:BG13529" /db_xref="UniProtKB/Swiss-Prot:O34524" /translation="MDIIRKISHFAGQTFGIWVIVFAVLGFSFPSLFTWISSYITIFL GIIMFGMGLTLQADDFKELVRKPWQVIIGVIAQYTIMPLVAFGLAFGLHLPAEIAVGV ILVGCCPGGTASNVMTFLAKGNTALSVAVTTISTLLAPVVTPLLIMLFAKEWLPVSPG SLFISILQAVLFPIIAGLIVKMFFRKQVAKAVHALPLVSVIGIVAIVSAVVSGNRENL LQSGLLIFSVVILHNGIGYLLGFLCAKLLKMDYPSQKAIAIEVGMQNSGLGAALATAH FSPLSAVPSAIFSVWHNLSGSMLATYWSKKVKKKQAGSKSSNLSL*" gene 2106490..2107455 /gene="yocS" /locus_tag="BSU_19350" /old_locus_tag="BSU19350" downshifts 2107443 /Source="Nicolas_upshifts" /id="D1067" /incds=0 /nref=42 /ntot=166 /MaxReadThrough="3.53218" /MaxDrop="5.09676" /score="30.279305" /energy="-16.4" /TU="U1581" /idTUdmin="U1581" /TUdmin="-22" /isTUend="TRUE" CDS complement(2107505..2108758) /gene="odhB" /locus_tag="BSU_19360" /old_locus_tag="BSU19360" /EC_number="2.3.1.61" /function="16.2: Construct biomass (Anabolism)" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:1508153, 2500417, 22720735, 26098117" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1508153, 2500417, 22720735, 26098117; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="2-oxoglutarate dehydrogenase complex (dihydrolipoamide transsuccinylase, E2 subunit)" /protein_id="NP_389818.2" /db_xref="EnsemblGenomes-Gn:BSU19360" /db_xref="EnsemblGenomes-Tr:CAB13828" /db_xref="GOA:P16263" /db_xref="InterPro:IPR000089" /db_xref="InterPro:IPR001078" /db_xref="InterPro:IPR003016" /db_xref="InterPro:IPR004167" /db_xref="InterPro:IPR006255" /db_xref="InterPro:IPR011053" /db_xref="InterPro:IPR036625" /db_xref="SubtiList:BG10273" /db_xref="UniProtKB/Swiss-Prot:P16263" /translation="MAEIKVPELAESISEGTIAQWLKQPGDYVEQGEYLLELETDKVN VELTAEESGVLQEVLKDSGDTVQVGEIIGTISEGAGESSAPAPTEKTESKESVKEEKQ AEPAAQEVSEEAQSEAKSRTIASPSARKLAREKGIDLSQVPTGDPLGRVRKQDVEAYE KPASKPAPQQKQQPQAQKAQQSFDKPVEVQKMSRRRQTIAKRLVEVQQTSAMLTTFNE VDMTAVMNLRKRRKDQFFEQNEVKLGFMSFFTKAVVAALKKYPLLNAEIQGDELIVKK FYDIGIAVAADEGLVVPVVRDADRLTFAGIEKEIGELAKKARNNKLTLSELQGGSFTI TNGGTFGSLMSTPILNSPQVGILGMHKIQLRPVAIDEERFENRPMMYIALSYDHRIVD GKEAVGFLVTIKNLLEDPEQLLLEG*" gene complement(2107505..2108758) /gene="odhB" /locus_tag="BSU_19360" /old_locus_tag="BSU19360" downshifts complement(2107519) /Source="Nicolas_upshifts" /id="D1068" /incds=0 /nref=200 /ntot=253 /MaxReadThrough="5.25481" /MaxDrop="7.42366" /score="11.7726103" /energy="-16.4" /TU="U1582" /idTUdmin="U1582" /TUdmin="-1694" /isTUend="FALSE" CDS complement(2108774..2111608) /gene="odhA" /locus_tag="BSU_19370" /old_locus_tag="BSU19370" /EC_number="1.2.4.2" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:1508153, 2500417" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1508153, 2500417; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="2-oxoglutarate dehydrogenase (E1 subunit)" /protein_id="NP_389819.3" /db_xref="EnsemblGenomes-Gn:BSU19370" /db_xref="EnsemblGenomes-Tr:CAB13829" /db_xref="GOA:P23129" /db_xref="InterPro:IPR001017" /db_xref="InterPro:IPR005475" /db_xref="InterPro:IPR011603" /db_xref="InterPro:IPR023784" /db_xref="InterPro:IPR029061" /db_xref="InterPro:IPR031717" /db_xref="InterPro:IPR032106" /db_xref="SubtiList:BG10272" /db_xref="UniProtKB/Swiss-Prot:P23129" /translation="MFQNSMKQRMNWEDFYGPNLGYALELYDQYTQDPNSIDPDLKEM FDELGAPPSDIKEASGTKEKGRVTADLIQKIASAVRLAEDIRTYGHLNASVNPLRKDE KKSELFPLSDYGLTEEEIKAIPASVICKDAPKNISNGLEAIQYLRNTYKRTISFEFDH VHDFKEREWLTRKIESGELFQKNSAEKLSAVLERLTEVEGFEQFLHRTFVGQKRFSIE GLDALVPVLDDIIAQSVKSGTTSVNIGMAHRGRLNVLAHVLGKPYEIIFSEFQHAPNK DLVPSEGSIGISYGWTGDVKYHLGANRELQDAETKSARITLANNPSHLEFINPIVEGS TRAAQETRTQSGYPVQDETKSLAILIHGDAAFPGEGIVAETLNLSSLKGYQVGGAIHI IANNMIGFTTESAESRSTKYASDLAKGYEIPIVHVNADDPEACLSAVKFAVEYRKTFN KDFLIDLIGYRRYGHNEMDEPSTTQPMLYDAVRKHPTVKQIFAEKLVKEGVVTEEVVQ NIEKSVTKRIEDAYQKVPSKKEHTACEIELPEPVSNGFPDVDTSIDFDVLRKLNGELI NWPESFNVFGKLKRILERRAKAFDDDRKVEWSLAESLAFASILKDGTPIRLTGQDSER GTFAQRNLVLHDSETGKEFVPLHHLSDCSTSFAVHNSPLSEGSVLGFEYGYNVHSPET LVLWEAQYGDFANAAQVYFDQFISAGRAKWGQKSGLVMLLPHGYEGQGPEHSSGRIER FLQLAAENNWTVANLTSAAQYFHILRRQAKMLLREEIRPLVIMTPKSLLRNPNTVSEV QELSESRFQPVYEQSGLSHDYEKVTRLVLSSGKVSIDISDHFNKLEDGKEWLHIARIE QLYPFPAKGVKELFAKLPNLKEIVWVQEEPQNMGAWGYISPYLTEIAPEGVSVQYIGR RRRSSPAEGDPTVHKKEQERIVSDSLTRKN*" gene complement(2108774..2111608) /gene="odhA" /locus_tag="BSU_19370" /old_locus_tag="BSU19370" promotor_-10 complement(2111703..2111722) /Source="Nicolas_upshift_promotors" /id="U1582" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.718281718281718" /psig=1 /xcortree=2228 /SigmaFactorBS="tataaaggttttttactattttgtgaacaatcaaGGTAGAAT caaattgcaaacagTGGTAAAATATCGTTGGAAGcgtttttattacataattttggac a" /listShort="odhA, odhB, S746, yocR" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2111718) /Source="Nicolas_upshifts" /id="U1582" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.718281718281718" /psig=1 /xcortree=2228 /SigmaFactorBS="tataaaggttttttactattttgtgaacaatcaaGGTAGAAT caaattgcaaacagTGGTAAAATATCGTTGGAAGcgtttttattacataattttggac a" /listShort="odhA, odhB, S746, yocR" /GFF_Attribute="listLong" S_feature complement(2111720..2111836) /Source="Nicolas_S_feature" /locus_tag="new_2111720_2111836_c" /HighExp="dia15, G150, G135, H2O2, Lbexp, dia0, Oxctl, LBGtran, G180, Heat" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S747" promotor_-35 complement(2111737..2111744) /Source="Nicolas_upshift_promotors" /id="U1582" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.718281718281718" /psig=1 /xcortree=2228 /SigmaFactorBS="tataaaggttttttactattttgtgaacaatcaaGGTAGAAT caaattgcaaacagTGGTAAAATATCGTTGGAAGcgtttttattacataattttggac a" /listShort="odhA, odhB, S746, yocR" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2111837..2113753) /gene="yojO" /locus_tag="BSU_19380" /old_locus_tag="BSU19380" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 23087684; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative activator of nitric oxide reductase" /protein_id="NP_389820.2" /db_xref="EnsemblGenomes-Gn:BSU19380" /db_xref="EnsemblGenomes-Tr:CAB13830" /db_xref="InterPro:IPR002035" /db_xref="InterPro:IPR036465" /db_xref="SubtiList:BG13567" /db_xref="UniProtKB/Swiss-Prot:O31849" /translation="MKFIKFNDSTIDSFLFMMLTDLAKTLTKSEAVEVEYGVQSYYNP FEKKIYMSHFWKDRAAEDMEAGLKSDVYLRSVGTRYSSLHEFANFLNDIHRHLTFKSF AKQLFMLLEDIRIEECIKRERPGTKHVFAKRKDMYRKHFSTQLTLNLERSIFTDALFC AIYFKLTAESPLETLPSMREDIDLMRPFIEQQLLRVYEADSTRQVLKIVEDLMDGLEE VLDKDMLNTYFFLPELDYAKAAEQPLFEEEKKAPKLSDDITLPKQSDGDEDIHEEEMP TWHRETEAPSKSFLQFDIEHGAKSDLGKDASREGDDGDQALGSVQGSARQTKRKDYSK LEALESQKDQPNGAGMADGKENKYAFPIYKEPQPATSEEELSYKQQAKTIESYQKRLK QMIQKTLEHKKTLPRTDLHAGRLNNKLLRYFTERNPRLFYKKQEPSSEIDAVFTLLVD CSASMFDKMDETKRGIVLFHEALKSVAVPHQIVGFWEDTNDATEKSQPNYFNTVIPFQ SSLRQDSGPAIMQLEPEEDNRDGYAIRQMTKKMLHRSEAQKFLIVFSDGEPAAFGYEQ NGIVDTSEAVIEARKRGIEVINVFLSNSEIEESQMKTIQDMYGKFSIFVPDVDQLPDV LYPLLKKLLHKSIG*" gene complement(2111837..2113753) /gene="yojO" /locus_tag="BSU_19380" /old_locus_tag="BSU19380" CDS complement(2113764..2114678) /gene="yojN" /locus_tag="BSU_19390" /old_locus_tag="BSU19390" /function="16.8: Protect" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15491156, 23087684; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative nitric-oxide reductase associated protein" /protein_id="NP_389821.1" /db_xref="EnsemblGenomes-Gn:BSU19390" /db_xref="EnsemblGenomes-Tr:CAB13831" /db_xref="GOA:O31850" /db_xref="InterPro:IPR001270" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR011704" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG13566" /db_xref="UniProtKB/Swiss-Prot:O31850" /translation="MNRKGNLSMTTQLQHLTLPEDIQQKLLSYKEQPISPEFQSLIGT SGYEAEDEAILFDAIIALAMGKNVLLKGPTGSGKTKLAETLSSYFHKPMHSVNCSVDL DAEALVGYKTIENQSGQATIEFVSGPVTKAMKEGHFLYIDEINMAKPETLPILNGVLD YRKMMTNPFTGEVIRAKSGFGVIAAINEGYVGTVPLNEALKNRFVIIDVPYIKGELLK QVLMSQSALKDEKLIDRFITLSSDLIVQANNGQVSEEAASIRALIDTCDLAAYIPPRR AIERGIVEKLDDDREKAAVRNIAETLFE*" gene complement(2113764..2114678) /gene="yojN" /locus_tag="BSU_19390" /old_locus_tag="BSU19390" promotor_-10 complement(2114682..2114701) /Source="Nicolas_upshift_promotors" /id="U1583" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.98001998001998" /psig=1 /xcortree=1833 /SigmaFactorBS="taacgagaagcagtaatatcatccaggcccttttgTATTGag catacaggggctttTTTAGTATACTCGTTAATGGaatatgaataggaaagggaatctg t" /listShort="yojN, yojO, S747" /listLong="odhA, odhB, S746" /label="promotor_-10" upshifts complement(2114697) /Source="Nicolas_upshifts" /id="U1583" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.98001998001998" /psig=1 /xcortree=1833 /SigmaFactorBS="taacgagaagcagtaatatcatccaggcccttttgTATTGag catacaggggctttTTTAGTATACTCGTTAATGGaatatgaataggaaagggaatctg t" /listShort="yojN, yojO, S747" /listLong="odhA, odhB, S746" promotor_-35 complement(2114718..2114722) /Source="Nicolas_upshift_promotors" /id="U1583" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.98001998001998" /psig=1 /xcortree=1833 /SigmaFactorBS="taacgagaagcagtaatatcatccaggcccttttgTATTGag catacaggggctttTTTAGTATACTCGTTAATGGaatatgaataggaaagggaatctg t" /listShort="yojN, yojO, S747" /listLong="odhA, odhB, S746" /label="promotor_-35" CDS complement(2114742..2115332) /gene="sodC" /locus_tag="BSU_19400" /old_locus_tag="BSU19400" /EC_number="1.15.1.1" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:15897454" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15897454; Product type lp: lipoprotein" /codon_start=1 /transl_table=11 /product="superoxide dismutase (exported lipoprotein)" /protein_id="NP_389822.1" /db_xref="EnsemblGenomes-Gn:BSU19400" /db_xref="EnsemblGenomes-Tr:CAB13832" /db_xref="GOA:O31851" /db_xref="InterPro:IPR001424" /db_xref="InterPro:IPR024134" /db_xref="InterPro:IPR036423" /db_xref="PDB:1S4I" /db_xref="PDB:1U3N" /db_xref="PDB:1XTL" /db_xref="PDB:1XTM" /db_xref="SubtiList:BG13565" /db_xref="UniProtKB/Swiss-Prot:O31851" /translation="MHRLLLLMMLTALGVAGCGQKKPPDPPNRVPEKKVVETSAFGHH VQLVNREGKAVGFIEIKESDDEGLDIHISANSLRPGASLGFHIYEKGSCVRPDFESAG GPFNPLNKEHGFNNPMGHHAGDLPNLEVGADGKVDVIMNAPDTSLKKGSKLNILDEDG SAFIIHEQADDYLTNPSGNSGARIVCGALLGNNEKQ*" gene complement(2114742..2115332) /gene="sodC" /locus_tag="BSU_19400" /old_locus_tag="BSU19400" CDS complement(2115425..2116669) /gene="cwlS" /locus_tag="BSU_19410" /old_locus_tag="BSU19410" /EC_number="3.5.1.-" /function="16.6: Maintain" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:16855244, 22139507" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16855244, 22139507; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="peptidoglycan hydrolase (cell wall-binding d,l-endopeptidase)" /protein_id="NP_389823.1" /db_xref="EnsemblGenomes-Gn:BSU19410" /db_xref="EnsemblGenomes-Tr:CAB13833" /db_xref="GOA:O31852" /db_xref="InterPro:IPR000064" /db_xref="InterPro:IPR018392" /db_xref="InterPro:IPR036779" /db_xref="SubtiList:BG13564" /db_xref="UniProtKB/Swiss-Prot:O31852" /translation="MKKKIVAGLAVSAVVGSSMAAAPAEAKTIKVKSGDSLWKLSRQY DTTISALKSENKLKSTVLYVGQSLKVPESSKKSTTSPSNSSKTSTYTVAYGDSLWMIA KNHKMSVSELKSLNSLSSDLIRPGQKLKIKGTSSSSGSNGSKKNSGSNSSGSSKSTYT VKLGDSLWKIANSLNMTVAELKTLNGLTSDTLYPKQVLKIKGSSSPKNGNSGSKKPSN SNPSKTTTYKVKAGDSLWKIANRLGVTVQSIRDKNNLSSDVLQIGQVLTISGASKSNP SNPTKPTKPKDNSGSNIQIGSKIDRMITEAKKYVGVPYRWGGNTPAGFDCSGFIYYLI NNVSSISRLSTAGYWNVMQKVSQPSVGDFVFFTTYKSGPSHMGIYLGGGDFIHASSSG VDISNLSNSYWKQRYLGARSYF*" gene complement(2115425..2116669) /gene="cwlS" /locus_tag="BSU_19410" /old_locus_tag="BSU19410" downshifts complement(2115427) /Source="Nicolas_upshifts" /id="D1069" /incds=0 /nref=20 /ntot=183 /MaxReadThrough="4.09529" /MaxDrop="3.77828" /score="11.0350171" /energy="-4.7" /TU="U1584,U1585" /idTUdmin="U1585" /TUdmin="-616" /isTUend="FALSE" promotor_-10 complement(2116732..2116750) /Source="Nicolas_upshift_promotors" /id="U1584" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp="0.971028971028971" /psig="0.971028971028971" /xcortree=3048 /SigmaFactorBS="gatgctgaaaatgctgcgccaaatgtttgaaaaggGTTTAAC TtgctgaaaaattGACGATAAAACAGTTGTGTgccatttttggaaacaaaatactagc t" /listShort="cwlS, sodC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2116745) /Source="Nicolas_upshifts" /id="U1584" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp="0.971028971028971" /psig="0.971028971028971" /xcortree=3048 /SigmaFactorBS="gatgctgaaaatgctgcgccaaatgtttgaaaaggGTTTAAC TtgctgaaaaattGACGATAAAACAGTTGTGTgccatttttggaaacaaaatactagc t" /listShort="cwlS, sodC" /GFF_Attribute="listLong" S_feature complement(2116747..2116967) /Source="Nicolas_S_feature" /locus_tag="new_2116747_2116967_c" /HighExp="S2, Lbstat, T2.30H, M0t90, HiOs, T3.0H, Etha, M40t90, T3.30H, SMMPr" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigH" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S748" promotor_-35 complement(2116763..2116770) /Source="Nicolas_upshift_promotors" /id="U1584" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp="0.971028971028971" /psig="0.971028971028971" /xcortree=3048 /SigmaFactorBS="gatgctgaaaatgctgcgccaaatgtttgaaaaggGTTTAAC TtgctgaaaaattGACGATAAAACAGTTGTGTgccatttttggaaacaaaatactagc t" /listShort="cwlS, sodC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(2116953..2116971) /Source="Nicolas_upshift_promotors" /id="U1585" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp=1 /psig=1 /xcortree=541 /SigmaFactorBS="agaacaggctttttgccatttcataagaatgcagagGAAGGG ATTtgacacgccgaTAGAGAATTGATTAGAAAAatagacaagaaaggaggagaaactg c" /listShort="S748, cwlS, sodC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2116967) /Source="Nicolas_upshifts" /id="U1585" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp=1 /psig=1 /xcortree=541 /SigmaFactorBS="agaacaggctttttgccatttcataagaatgcagagGAAGGG ATTtgacacgccgaTAGAGAATTGATTAGAAAAatagacaagaaaggaggagaaactg c" /listShort="S748, cwlS, sodC" /GFF_Attribute="listLong" promotor_-35 complement(2116983..2116991) /Source="Nicolas_upshift_promotors" /id="U1585" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp=1 /psig=1 /xcortree=541 /SigmaFactorBS="agaacaggctttttgccatttcataagaatgcagagGAAGGG ATTtgacacgccgaTAGAGAATTGATTAGAAAAatagacaagaaaggaggagaaactg c" /listShort="S748, cwlS, sodC" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2117051..2118268) /gene="yojK" /locus_tag="BSU_19420" /old_locus_tag="BSU19420" /EC_number="2.4.1.-" /function="16.6: Maintain" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative YDP-glycosyltransferase" /protein_id="NP_389824.2" /db_xref="EnsemblGenomes-Gn:BSU19420" /db_xref="EnsemblGenomes-Tr:CAB13834" /db_xref="GOA:O31853" /db_xref="InterPro:IPR002213" /db_xref="InterPro:IPR006326" /db_xref="SubtiList:BG13563" /db_xref="UniProtKB/Swiss-Prot:O31853" /translation="MANVLMIGFPGEGHINPSIGVMKELKSRGENITYYAVKEYKEKI TALDIEFREYHDFRGDYFGKNATGDEERDFTEMLCAFLKACKDIATHIYEEVKHESYD YVIYDHHLLAGKVIANMLKLPRFSLCTTFAMNEEFAKEMMGAYMKGSLEDSPHYESYQ QLAETLNADFQAEIKKPFDVFLADGDLTIVFTSRGFQPLAEQFGERYVFVGPSITERA GNNDFPFDQIDNENVLFISMGTIFNNQKQFFNQCLEVCKDFDGKVVLSIGKHIKTSEL NDIPENFIVRPYVPQLEILKRASLFVTHGGMNSTSEGLYFETPLVVIPMGGDQFVVAD QVEKVGAGKVIKKEELSESLLKETIQEVMNNRSYAEKAKEIGQSLKAAGGSKKAADSI LEAVKQKTQSANA*" gene complement(2117051..2118268) /gene="yojK" /locus_tag="BSU_19420" /old_locus_tag="BSU19420" downshifts complement(2117077) /Source="Nicolas_upshifts" /id="D1070" /incds=0 /nref=14 /ntot=145 /MaxReadThrough="1.49168" /MaxDrop="4.07727" /score="9.41396656" /energy="-14.4" /TU="NA" /idTUdmin="U1586" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(2118301..2118320) /Source="Nicolas_upshift_promotors" /id="U1586" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.498501498501498" /psig="0.994005994005994" /xcortree=2220 /SigmaFactorBS="atatatgatgaatattaattaagtgaaaTACTTTACctgttt atgcattTATAGTACCGTATAAAATATtacataaattctcaaaggaagggtgctgccg c" /listShort="yojK" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2118309) /Source="Nicolas_upshifts" /id="U1586" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.498501498501498" /psig="0.994005994005994" /xcortree=2220 /SigmaFactorBS="atatatgatgaatattaattaagtgaaaTACTTTACctgttt atgcattTATAGTACCGTATAAAATATtacataaattctcaaaggaagggtgctgccg c" /listShort="yojK" /GFF_Attribute="listLong" promotor_-35 complement(2118334..2118341) /Source="Nicolas_upshift_promotors" /id="U1586" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.498501498501498" /psig="0.994005994005994" /xcortree=2220 /SigmaFactorBS="atatatgatgaatattaattaagtgaaaTACTTTACctgttt atgcattTATAGTACCGTATAAAATATtacataaattctcaaaggaagggtgctgccg c" /listShort="yojK" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2118504..2119127) /gene="cdaS" /locus_tag="BSU_19430" /old_locus_tag="BSU19430" /EC_number="2.7.7.85" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:21566650, 23192352, 24939848, 27252699, 27790204, 28751888" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 21566650, 23192352, 24939848, 27252699, 27790204, 28751888; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="spore diadenylate cyclase" /protein_id="NP_389825.3" /db_xref="EnsemblGenomes-Gn:BSU19430" /db_xref="EnsemblGenomes-Tr:CAB13835" /db_xref="GOA:O31854" /db_xref="InterPro:IPR003390" /db_xref="InterPro:IPR014046" /db_xref="InterPro:IPR019457" /db_xref="InterPro:IPR034693" /db_xref="InterPro:IPR036888" /db_xref="SubtiList:BG13562" /db_xref="UniProtKB/Swiss-Prot:O31854" /translation="MKAMRYEQISENAFKGKIQVYLEQILGDASLILKTLHEKDQCLL CELDDLGHVFQDMQGIASSFYLQSYIEEFTPAFIELAKAIKALSEHKHGALIVIERAD PVERFIQKGTSLHAEISSSLIESIFFPGNPLHDGALLVRENKLVSAANVLPLTTKEVD IHLGTRHRAALGMSGYTDALVLVVSEETGKMSFAKDGVLYPLISPRT*" gene complement(2118504..2119127) /gene="cdaS" /locus_tag="BSU_19430" /old_locus_tag="BSU19430" S_feature complement(2119128..2119278) /Source="Nicolas_S_feature" /locus_tag="new_2119128_2119278_c" /HighExp="S8, S5, S7, S6, Etha, S4, M9-stat, S3, C30, Gly" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigB" /TUshortPSig="0.998" /TUlongSig="NA" /TUlongPSig="NA" /label="S749" promotor_-35 2119154..2119160 /Source="Nicolas_upshift_promotors" /id="U1587" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=898 /SigmaFactorBS="gctcatagcgcatagccttcatctcctgtttaaatttccaac ttttcaCGAATGCttatcttattgatGCACATTCTATTggtaaaggagggatgtaaag a" /listShort="S750, norM" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 2119166 /Source="Nicolas_upshifts" /id="U1587" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=898 /SigmaFactorBS="gctcatagcgcatagccttcatctcctgtttaaatttccaac ttttcaCGAATGCttatcttattgatGCACATTCTATTggtaaaggagggatgtaaag a" /listShort="S750, norM" /GFF_Attribute="listLong" promotor_-10 2119174..2119185 /Source="Nicolas_upshift_promotors" /id="U1587" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=898 /SigmaFactorBS="gctcatagcgcatagccttcatctcctgtttaaatttccaac ttttcaCGAATGCttatcttattgatGCACATTCTATTggtaaaggagggatgtaaag a" /listShort="S750, norM" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 2119192..2119200 /Source="Nicolas_upshift_promotors" /id="U1588" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.995004995004995" /psig="0.995004995004995" /xcortree=539 /SigmaFactorBS="atcttattgatgcacattctattggtaaaGGAGGGATGtaaa gaatggaAATCGAAAGAATCATTCAGtatatttgcacctttttaggcgtgatttcgct t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_no_box 2119208..2119308 /Source="Nicolas_upshift_promotors" /id="U1589" /multdbtbs="-" /comp="M21" /sig="Sig-" /pcomp="0.56043956043956" /psig="0.006993006993007" /xcortree=1480 /SigmaFactorBS="tggaaatcgaaagaatcattcagtatatttgcacctttttag gcgtgatttcgctttcttttatttatgcccaaatgtttagaaaaacgaaaccgacaaa a" /listShort="S750, norM" /GFF_Attribute="listLong" /label="promotor_no_box" promotor_-10 2119212..2119230 /Source="Nicolas_upshift_promotors" /id="U1588" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.995004995004995" /psig="0.995004995004995" /xcortree=539 /SigmaFactorBS="atcttattgatgcacattctattggtaaaGGAGGGATGtaaa gaatggaAATCGAAAGAATCATTCAGtatatttgcacctttttaggcgtgatttcgct t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2119223 /Source="Nicolas_upshifts" /id="U1588" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.995004995004995" /psig="0.995004995004995" /xcortree=539 /SigmaFactorBS="atcttattgatgcacattctattggtaaaGGAGGGATGtaaa gaatggaAATCGAAAGAATCATTCAGtatatttgcacctttttaggcgtgatttcgct t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 complement(2119261..2119279) /Source="Nicolas_upshift_promotors" /id="U1590" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=740 /SigmaFactorBS="aaaaagcaatgaacgccgggcctattctttttttgtcGGTTT CGtttttctaaacatttGGGCATAAATAAAAGAAAGcgaaatcacgcctaaaaaggtg c" /listShort="S749, yojJ" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 2119268..2119353 /Source="Nicolas_S_feature" /locus_tag="new_2119268_2119353" /HighExp="S8, S7, S4, S5, S6, BT, S3, T5.0H, S2, ferm" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="Sig-, SigGF" /TUshortPSig="0.00699, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S750" upshifts 2119268 /Source="Nicolas_upshifts" /id="U1589" /multdbtbs="-" /comp="M21" /sig="Sig-" /pcomp="0.56043956043956" /psig="0.006993006993007" /xcortree=1480 /SigmaFactorBS="tggaaatcgaaagaatcattcagtatatttgcacctttttag gcgtgatttcgctttcttttatttatgcccaaatgtttagaaaaacgaaaccgacaaa a" /listShort="S750, norM" /GFF_Attribute="listLong" upshifts complement(2119278) /Source="Nicolas_upshifts" /id="U1590" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=740 /SigmaFactorBS="aaaaagcaatgaacgccgggcctattctttttttgtcGGTTT CGtttttctaaacatttGGGCATAAATAAAAGAAAGcgaaatcacgcctaaaaaggtg c" /listShort="S749, yojJ" /GFF_Attribute="listLong" promotor_-35 complement(2119295..2119301) /Source="Nicolas_upshift_promotors" /id="U1590" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=740 /SigmaFactorBS="aaaaagcaatgaacgccgggcctattctttttttgtcGGTTT CGtttttctaaacatttGGGCATAAATAAAAGAAAGcgaaatcacgcctaaaaaggtg c" /listShort="S749, yojJ" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 2119329..2119336 /Source="Nicolas_upshift_promotors" /id="U1591" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.634365634365634" /psig=1 /xcortree=2408 /SigmaFactorBS="cgaaaccgacaaaaaaagaataggcccggcgttcATTGCTTT ttatacataaaaTGTTATAATTTCTCTCGTTAtgaaaaagaaacggagatcaatgtat g" /listShort="norM, rsbRC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2119349..2119368 /Source="Nicolas_upshift_promotors" /id="U1591" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.634365634365634" /psig=1 /xcortree=2408 /SigmaFactorBS="cgaaaccgacaaaaaaagaataggcccggcgttcATTGCTTT ttatacataaaaTGTTATAATTTCTCTCGTTAtgaaaaagaaacggagatcaatgtat g" /listShort="norM, rsbRC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2119355 /Source="Nicolas_upshifts" /id="U1591" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.634365634365634" /psig=1 /xcortree=2408 /SigmaFactorBS="cgaaaccgacaaaaaaagaataggcccggcgttcATTGCTTT ttatacataaaaTGTTATAATTTCTCTCGTTAtgaaaaagaaacggagatcaatgtat g" /listShort="norM, rsbRC" /GFF_Attribute="listLong" CDS 2119393..2120751 /gene="mdtK" /locus_tag="BSU_19440" /old_locus_tag="BSU19440" /function="16.1: Circulate" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 14766544, 15849754, 15855508, 16850406, 16954325, 17114254; Product type t : transporter" /codon_start=1 /transl_table=11 /product="Na+-driven efflux MatE family protein" /protein_id="NP_389826.1" /db_xref="EnsemblGenomes-Gn:BSU19440" /db_xref="EnsemblGenomes-Tr:CAB13836" /db_xref="GOA:O31855" /db_xref="InterPro:IPR002528" /db_xref="SubtiList:BG13561" /db_xref="UniProtKB/Swiss-Prot:O31855" /translation="MKETQNAREKIKQLLHILIPIFITQAGLSLITFLDTVMSGKVSP ADLAGVAIGSSLWTPVYTGLAGILMAVTPIVAQLLGAEKKQKIPFTVLQAVYVAALLS IAVLVIGYAAVDLILGRLNLDIHVHQIAKHFLGFLSLGIFPLFVYTVLRSFIDSLGKT RVTMMITLSSLPINFVLNYVFIFGKFGMPALGGVGAGLASALTYWCICIISFFIIHKN APFSEYGIFLTMYKFSWKACKNLLKIGLPIGFAVFFETSIFAAVTLLMSHFHTVTIAS HQAAMNFASLLYMLPLSVSMALTIVVGFEAGAARFKDARSYSLIGIMMAIGFSLFTAA CILLFREQIAGMYTSDPDVLRLTQHFLIYALFFQLSDAVAAPIQGALRGYKDVNYTLA AAFVSYWVIGLPVGYMVGTFTSLGAFGYWIGLIAGLAAGAVGLFFRLAKLQKRYSQKQ HI*" gene 2119393..2120751 /gene="mdtK" /locus_tag="BSU_19440" /old_locus_tag="BSU19440" promotor_-10 complement(2119735..2119746) /Source="Nicolas_upshift_promotors" /id="U1592" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=946 /SigmaFactorBS="aaagcctaaaaagtgtttagcaatctgatgcacgTGAATATc aaggttcaatcgGCCAAGAATAAGgtcaactgcagcatatccaatcactaaaacggcg a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2119740) /Source="Nicolas_upshifts" /id="U1592" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=946 /SigmaFactorBS="aaagcctaaaaagtgtttagcaatctgatgcacgTGAATATc aaggttcaatcgGCCAAGAATAAGgtcaactgcagcatatccaatcactaaaacggcg a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(2119760..2119766) /Source="Nicolas_upshift_promotors" /id="U1592" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=946 /SigmaFactorBS="aaagcctaaaaagtgtttagcaatctgatgcacgTGAATATc aaggttcaatcgGCCAAGAATAAGgtcaactgcagcatatccaatcactaaaacggcg a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" CDS 2120767..2121615 /gene="rsbRC" /locus_tag="BSU_19450" /old_locus_tag="BSU19450" /function="16.8: Protect" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:15312768, 15583165, 17158665, 20935101, 22287516, 24599254" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15312768, 15583165, 17158665, 20935101, 22287516, 24599254; Product type f : factor" /codon_start=1 /transl_table=11 /product="co-antagonist of RsbT; component of the anxiosome (stressosome)" /protein_id="NP_389827.1" /db_xref="EnsemblGenomes-Gn:BSU19450" /db_xref="EnsemblGenomes-Tr:CAB13837" /db_xref="InterPro:IPR002645" /db_xref="InterPro:IPR036513" /db_xref="SubtiList:BG13560" /db_xref="UniProtKB/Swiss-Prot:O31856" /translation="MAKNKKLFEYLSQHAETISSTWYETIEETDPNSIYASTDPVVIH NLKSQNLAFNYKINRIFIDDEDVYLPILKEWAFEVTQDQEHLKTPIHYIIREFVRVRD LYVSYVKEFVHLNQNTVKSEEAEDLYHALIKAFDLVIHIFIEEMYKNTSLQLQAQKDM ITELSAPVIVLFHSVGLLPLIGDIDTVRAKLIMENTLHQCAKKKVTQLYIDLSGVAVI DTMVAHQLFSLIEALRLIGVSSTLSGIRPEIAQTAVQLGLSFEGISLRSTLASAIASD LKLKKV*" gene 2120767..2121615 /gene="rsbRC" /locus_tag="BSU_19450" /old_locus_tag="BSU19450" promotor_-10 complement(2121031..2121050) /Source="Nicolas_upshift_promotors" /id="U1593" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.994005994005994" /psig="0.994005994005994" /xcortree=1361 /SigmaFactorBS="aattctttcacataagaaacatataaATCTCTCACtctgaca aactccCGAATAATATAGTGGATAGGagtttttaaatgctcttgatcctgtgtgactt c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2121038) /Source="Nicolas_upshifts" /id="U1593" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.994005994005994" /psig="0.994005994005994" /xcortree=1361 /SigmaFactorBS="aattctttcacataagaaacatataaATCTCTCACtctgaca aactccCGAATAATATAGTGGATAGGagtttttaaatgctcttgatcctgtgtgactt c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(2121064..2121072) /Source="Nicolas_upshift_promotors" /id="U1593" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.994005994005994" /psig="0.994005994005994" /xcortree=1361 /SigmaFactorBS="aattctttcacataagaaacatataaATCTCTCACtctgaca aactccCGAATAATATAGTGGATAGGagtttttaaatgctcttgatcctgtgtgactt c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 2121578 /Source="Nicolas_upshifts" /id="D1071" /incds=0 /nref=10 /ntot=138 /MaxReadThrough="1.62054" /MaxDrop="3.13267" /score="12.3887642" /energy="-14" /TU="NA" /idTUdmin="U1591" /TUdmin=0 /isTUend="TRUE" downshifts complement(2121610) /Source="Nicolas_upshifts" /id="D1072" /incds=0 /nref=1 /ntot=13 /MaxReadThrough="1.55562" /MaxDrop="4.60101" /score="23.8391861" /energy="-13.7" /TU="NA" /idTUdmin="U1594" /TUdmin=22 /isTUend="TRUE" CDS complement(2121641..2122306) /gene="bshBB" /locus_tag="BSU_19460" /old_locus_tag="BSU19460" /EC_number="3.5.1.-" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:15136574, 20308541" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15136574, 20308541; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="malate N-acetylglucosamine deacetylase (second enzyme)" /protein_id="YP_054582.2" /db_xref="EnsemblGenomes-Gn:BSU19460" /db_xref="EnsemblGenomes-Tr:CAB13838" /db_xref="GOA:O31857" /db_xref="InterPro:IPR003737" /db_xref="InterPro:IPR023841" /db_xref="InterPro:IPR024078" /db_xref="SubtiList:BG13559" /db_xref="UniProtKB/Swiss-Prot:O31857" /translation="MKEHVLVILPHPDDESYGVAGLIALNRKKDIPVTYACATLGEMG RNMGDPFFANRETLPLLRKQELINACKEMDINDLRMLGLRDKTLEFEDDEYLADIMEE IIDDVKPSLIVTFYPGHGVHPDHDACGEAVIRALYRKKKEDRPRTICMAITRNREEVL GEADVVLDIKEVADIKMNALRAHRTQTEGMLRELEEKLKNNEPVMATWFEEEIYWTYQ WND*" gene complement(2121641..2122306) /gene="bshBB" /locus_tag="BSU_19460" /old_locus_tag="BSU19460" downshifts complement(2121655) /Source="Nicolas_upshifts" /id="D1073" /incds=0 /nref=189 /ntot=251 /MaxReadThrough="3.68743" /MaxDrop="7.13247" /score="23.8391861" /energy="-13.7" /TU="U1594" /idTUdmin="U1596" /TUdmin="-1" /isTUend="TRUE" CDS complement(2122325..2122675) /gene="yojF" /locus_tag="BSU_19470" /old_locus_tag="BSU19470" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 20308541" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function (bacillithiol synthesis operon)" /protein_id="NP_389829.1" /db_xref="EnsemblGenomes-Gn:BSU19470" /db_xref="EnsemblGenomes-Tr:CAB13839" /db_xref="InterPro:IPR014934" /db_xref="InterPro:IPR036492" /db_xref="PDB:1NJH" /db_xref="SubtiList:BG13558" /db_xref="UniProtKB/Swiss-Prot:O31858" /translation="MKAIIKEDVQASLERYADRPVYIHLETTTGSYSAHLNEKNMTVV AYIRNAKVTYHQAKIKGNGPYRVGLKTEEGWIYAEGLTEYTVDEENRLLMAGHLPGGK LAISLQISEKPFTV*" gene complement(2122325..2122675) /gene="yojF" /locus_tag="BSU_19470" /old_locus_tag="BSU19470" CDS complement(2122672..2122950) /gene="yoyC" /locus_tag="BSU_19479" /old_locus_tag="BSU19479" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 20308541, 22720735" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="YP_003097741.1" /db_xref="EnsemblGenomes-Gn:BSU19479" /db_xref="EnsemblGenomes-Tr:CAX52638" /db_xref="UniProtKB/Swiss-Prot:O68260" /translation="MDNDKEIVKAYASLWNNRSLAHDDAEAVAEAIDLELLDKRTHPR LRKPMLEKYFAAIQRIVNSQLEPAVKYQLVKLHTERAEYLKEERGEQS*" gene complement(2122672..2122950) /gene="yoyC" /locus_tag="BSU_19479" /old_locus_tag="BSU19479" promotor_-10 complement(2122977..2122996) /Source="Nicolas_upshift_promotors" /id="U1594" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.512487512487512" /psig="0.94105894105894" /xcortree=2009 /SigmaFactorBS="gtggaaacgggcgtcaaaaagccattgaggcctttgGCTTTT CagctgatgcatataTTATGTATAATCATTTCATGtatgtaagacataaaggagcaag a" /listShort="yoyC, yojF, yojG" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2122993) /Source="Nicolas_upshifts" /id="U1594" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.512487512487512" /psig="0.94105894105894" /xcortree=2009 /SigmaFactorBS="gtggaaacgggcgtcaaaaagccattgaggcctttgGCTTTT CagctgatgcatataTTATGTATAATCATTTCATGtatgtaagacataaaggagcaag a" /listShort="yoyC, yojF, yojG" /GFF_Attribute="listLong" promotor_-35 complement(2123011..2123017) /Source="Nicolas_upshift_promotors" /id="U1594" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.512487512487512" /psig="0.94105894105894" /xcortree=2009 /SigmaFactorBS="gtggaaacgggcgtcaaaaagccattgaggcctttgGCTTTT CagctgatgcatataTTATGTATAATCATTTCATGtatgtaagacataaaggagcaag a" /listShort="yoyC, yojF, yojG" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2123026..2123922) /gene="yojE" /locus_tag="BSU_19480" /old_locus_tag="BSU19480" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406, 22226636, 23944997; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative N-acetylated toxic metabolites" /protein_id="NP_389830.2" /db_xref="EnsemblGenomes-Gn:BSU19480" /db_xref="EnsemblGenomes-Tr:CAB13840" /db_xref="GOA:O31859" /db_xref="InterPro:IPR000620" /db_xref="InterPro:IPR004626" /db_xref="SubtiList:BG13557" /db_xref="UniProtKB/Swiss-Prot:O31859" /translation="MQHAETKKGVIYTAVSFIMWGLFPLYWKLLEQLPALDILAHRII WSFVFMCIVLFFLRQWKIGWQELRSLKKNGGILSLFLASILISINWFVYIWAVNHGFL LEASLGYYINPLVSVLLGILFLKEKLNRLQLVAVSIAAAGVIISAFQYGSIPYVALLL AFSFGLYGLSKKRTSLPSAIGLTLETFMIMPIALGYLLFSGHVQPAGAESGGTWLLLF LAGVFTALPLLLFAEGAKRLPLYQVGILQYIAPTITLLIGLFVYHEPFSSSKAFTFSC IWAALLLFTFSQVKWKRASKSH*" gene complement(2123026..2123922) /gene="yojE" /locus_tag="BSU_19480" /old_locus_tag="BSU19480" promotor_-35 2123764..2123773 /Source="Nicolas_upshift_promotors" /id="U1595" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1337 /SigmaFactorBS="actcctgccatcctattttccattgccgcaagaaaaaaagTA CGATACACataaaaacaaaagACCATATAATACGATGAGCCaaaatatcaagagccgg c" /listShort="S751, gerT" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 2123784 /Source="Nicolas_upshifts" /id="U1595" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1337 /SigmaFactorBS="actcctgccatcctattttccattgccgcaagaaaaaaagTA CGATACACataaaaacaaaagACCATATAATACGATGAGCCaaaatatcaagagccgg c" /listShort="S751, gerT" /GFF_Attribute="listLong" promotor_-10 2123787..2123806 /Source="Nicolas_upshift_promotors" /id="U1595" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1337 /SigmaFactorBS="actcctgccatcctattttccattgccgcaagaaaaaaagTA CGATACACataaaaacaaaagACCATATAATACGATGAGCCaaaatatcaagagccgg c" /listShort="S751, gerT" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 2123802..2124020 /Source="Nicolas_S_feature" /locus_tag="new_2123802_2124020" /HighExp="S6, S8, S7, BT, S5, B36, G/S, Pyr, B60, SMMPr" /AntisenseName="yojE" /AntisenseCor="-0.562105310907978" /AntisenseRegPval="-23.1" /CDS_PredictionProba="NA" /TUshortSig="SigK" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S751" promotor_-10 complement(2123946..2123965) /Source="Nicolas_upshift_promotors" /id="U1596" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.93006993006993" /psig=1 /xcortree=2446 /SigmaFactorBS="aaacattgtcttcacatcctttcttcacggacaaaatagtat ATGCCCACcagatctttcaCGTGATATAATATAAGATGCtctaaagaaaggcagggat a" /listShort="yojE, yoyC, yojF, yojG" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2123966) /Source="Nicolas_upshifts" /id="U1596" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.93006993006993" /psig=1 /xcortree=2446 /SigmaFactorBS="aaacattgtcttcacatcctttcttcacggacaaaatagtat ATGCCCACcagatctttcaCGTGATATAATATAAGATGCtctaaagaaaggcagggat a" /listShort="yojE, yoyC, yojF, yojG" /GFF_Attribute="listLong" promotor_-35 complement(2123977..2123984) /Source="Nicolas_upshift_promotors" /id="U1596" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.93006993006993" /psig=1 /xcortree=2446 /SigmaFactorBS="aaacattgtcttcacatcctttcttcacggacaaaatagtat ATGCCCACcagatctttcaCGTGATATAATATAAGATGCtctaaagaaaggcagggat a" /listShort="yojE, yoyC, yojF, yojG" /GFF_Attribute="listLong" /label="promotor_-35" CDS 2124021..2124494 /gene="gerT" /locus_tag="BSU_19490" /old_locus_tag="BSU19490" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:17720779" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 17720779; Product type s: structure" /codon_start=1 /transl_table=11 /product="component of the spore coat" /protein_id="YP_054583.1" /db_xref="EnsemblGenomes-Gn:BSU19490" /db_xref="EnsemblGenomes-Tr:CAE01457" /db_xref="GOA:Q7WY67" /db_xref="InterPro:IPR008978" /db_xref="SubtiList:BG14190" /db_xref="UniProtKB/Swiss-Prot:Q7WY67" /translation="MFEWNKYFPFHNQFSKEALKKADPKEVETYVNRVMESVFGSDYA AQFPFRDPLPQKEHPAKPDAKPDVKPDIDIFETADHVFVKVPISEEWLEQVRIKHTSH ELWLENLPRADHPKKVNLPCLVKRKGTKAVYKDGLLEVMFQKQQDYNMSEVEIIR*" gene 2124021..2124494 /gene="gerT" /locus_tag="BSU_19490" /old_locus_tag="BSU19490" downshifts 2124491 /Source="Nicolas_upshifts" /id="D1074" /incds=0 /nref=23 /ntot=53 /MaxReadThrough="-0.0703700000000005" /MaxDrop="9.27889" /score="40.8456275" /energy="-16.6" /TU="NA" /idTUdmin="U1595" /TUdmin=7 /isTUend="TRUE" CDS complement(2124529..2124765) /gene="yojB" /locus_tag="BSU_19510" /old_locus_tag="BSU19510" /function="18: Unknown function" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_389832.1" /db_xref="EnsemblGenomes-Gn:BSU19510" /db_xref="EnsemblGenomes-Tr:CAB13842" /db_xref="GOA:O31861" /db_xref="SubtiList:BG13555" /db_xref="UniProtKB/Swiss-Prot:O31861" /translation="MYPHHSYLRGIPGPAGYPARSPFLFGAPLVGGLLGGFLGSALFN YSRPYAYPPGPYGYGGGPYGFGAGVPYGGYPGFY*" gene complement(2124529..2124765) /gene="yojB" /locus_tag="BSU_19510" /old_locus_tag="BSU19510" downshifts complement(2124537) /Source="Nicolas_upshifts" /id="D1075" /incds=0 /nref=37 /ntot=68 /MaxReadThrough="2.10188" /MaxDrop="7.8003" /score="35.4403926" /energy="-16.6" /TU="NA" /idTUdmin="U1597" /TUdmin=1 /isTUend="TRUE" promotor_-10 complement(2124788..2124807) /Source="Nicolas_upshift_promotors" /id="U1597" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=1296 /SigmaFactorBS="ggcttgtgatgtaacaatcatagacagtccgtaGCCCAATCG TttttcttccttgcTGAATACTTTACGTATAGGCagacataaaggaggaaaaaatcat g" /listShort="yojB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2124803) /Source="Nicolas_upshifts" /id="U1597" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=1296 /SigmaFactorBS="ggcttgtgatgtaacaatcatagacagtccgtaGCCCAATCG TttttcttccttgcTGAATACTTTACGTATAGGCagacataaaggaggaaaaaatcat g" /listShort="yojB" /GFF_Attribute="listLong" promotor_-35 complement(2124821..2124830) /Source="Nicolas_upshift_promotors" /id="U1597" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=1296 /SigmaFactorBS="ggcttgtgatgtaacaatcatagacagtccgtaGCCCAATCG TttttcttccttgcTGAATACTTTACGTATAGGCagacataaaggaggaaaaaatcat g" /listShort="yojB" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2124850..2126184) /gene="yojA" /locus_tag="BSU_19520" /old_locus_tag="BSU19520" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 3020045, 15849754, 16850406, 17114254; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative H+/anion permease" /protein_id="NP_389833.1" /db_xref="EnsemblGenomes-Gn:BSU19520" /db_xref="EnsemblGenomes-Tr:CAB13843" /db_xref="GOA:O31862" /db_xref="InterPro:IPR003474" /db_xref="SubtiList:BG13554" /db_xref="UniProtKB/Swiss-Prot:O31862" /translation="MPILIVAVGVLILLFLIIKVKLNTFVSLIVVSFLVAIGLGMDIN KIVLSIETGIGGQLGHLALVFGLGAMLGRLVSDAGGGYRIAITLIDKFGRKRIQAAVV VASFIIGIALFFEVGLVLLIPIVYAIAKELKMPFLYLGIPMAAALNVTHGFLPPHPAP TAISVAYGAHIGQVLLFGIIIAVPTTVIAGPLFNKFAMKRFPGAYQKHGNLSGLGPRK EFQLDETPGFAISAVTSLFPVIFMAMATIFSLLLSEHSKGKDIIEFIGTPGTAMLISL LLALYTMGYARKISMQEIGRSISESISQIAMMLLIIGGGGAFKQVLIDGGVGDYVADF FRQTNMSPLFVAWTIAAVLRLCLGSATVAALTTAGMAAPLMEAGSVNPALMVLATGAG SVIACHVNDAGFWMVKEFFGLSMKETFQTWTLLTTVLSVTGLGCVLLAGLVM*" gene complement(2124850..2126184) /gene="yojA" /locus_tag="BSU_19520" /old_locus_tag="BSU19520" S_feature complement(2126185..2126320) /Source="Nicolas_S_feature" /locus_tag="new_2126185_2126320_c" /HighExp="M0t90, M40t90, Lbtran, S1, dia5, Mt0, T0.0H, BI, Lbstat, T0.30H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.25781100000000001" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S752" promotor_-10 complement(2126317..2126336) /Source="Nicolas_upshift_promotors" /id="U1598" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.999000999001" /psig=1 /xcortree=324 /SigmaFactorBS="gtaggtaatcgagacaagctcataaaaacGATTGACAgtcat tgattaggaGATTAGTATGAACATATTAGttgatcaaaagataacaatcatataacca a" /listShort="S752, yojA, yojB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2126327) /Source="Nicolas_upshifts" /id="U1598" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.999000999001" /psig=1 /xcortree=324 /SigmaFactorBS="gtaggtaatcgagacaagctcataaaaacGATTGACAgtcat tgattaggaGATTAGTATGAACATATTAGttgatcaaaagataacaatcatataacca a" /listShort="S752, yojA, yojB" /GFF_Attribute="listLong" promotor_-35 complement(2126351..2126358) /Source="Nicolas_upshift_promotors" /id="U1598" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.999000999001" /psig=1 /xcortree=324 /SigmaFactorBS="gtaggtaatcgagacaagctcataaaaacGATTGACAgtcat tgattaggaGATTAGTATGAACATATTAGttgatcaaaagataacaatcatataacca a" /listShort="S752, yojA, yojB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 2126416..2126423 /Source="Nicolas_upshift_promotors" /id="U1599" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.638361638361638" /psig="0.996003996003996" /xcortree=2766 /SigmaFactorBS="tacctaccgcctaacccaatgatttattagttataTGTTGAT TaacttttggttataTGTTATGTTTTTTAAAGTTGactgccaatcattatatctctcc a" /listShort="S753, yodA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2126438..2126457 /Source="Nicolas_upshift_promotors" /id="U1599" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.638361638361638" /psig="0.996003996003996" /xcortree=2766 /SigmaFactorBS="tacctaccgcctaacccaatgatttattagttataTGTTGAT TaacttttggttataTGTTATGTTTTTTAAAGTTGactgccaatcattatatctctcc a" /listShort="S753, yodA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2126441 /Source="Nicolas_upshifts" /id="U1599" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.638361638361638" /psig="0.996003996003996" /xcortree=2766 /SigmaFactorBS="tacctaccgcctaacccaatgatttattagttataTGTTGAT TaacttttggttataTGTTATGTTTTTTAAAGTTGactgccaatcattatatctctcc a" /listShort="S753, yodA" /GFF_Attribute="listLong" S_feature 2126442..2126548 /Source="Nicolas_S_feature" /locus_tag="new_2126442_2126548" /HighExp="M0t90, M40t90, LoTm, Salt, Cold, BI, HPh, LBGstat, GM 60, GM 45" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.996" /TUlongSig="NA" /TUlongPSig="NA" /label="S753" CDS 2126549..2126938 /gene="yodA" /locus_tag="BSU_19530" /old_locus_tag="BSU19530" /EC_number="5.3.2.-" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 22720735; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative tautomerase" /protein_id="NP_389834.1" /db_xref="EnsemblGenomes-Gn:BSU19530" /db_xref="EnsemblGenomes-Tr:CAB13844" /db_xref="GOA:O34882" /db_xref="InterPro:IPR004370" /db_xref="InterPro:IPR014347" /db_xref="SubtiList:BG13530" /db_xref="UniProtKB/Swiss-Prot:O34882" /translation="MPLLRFDVIEGRDEKSLQLLLDTAHQAMVEAFGVPERDRYQIVH QHPANELIIQDAGLGFQRTKDMVIISMTSKARTESQKEKLYALLAERLEKKCEISPDD LMVSITENGDADWSFGLGEAQFLNGKL*" gene 2126549..2126938 /gene="yodA" /locus_tag="BSU_19530" /old_locus_tag="BSU19530" downshifts 2126948 /Source="Nicolas_upshifts" /id="D1076" /incds=0 /nref=1 /ntot=8 /MaxReadThrough="1.20831" /MaxDrop="2.65754" /score="14.4455719" /energy="-13.2" /TU="NA" /idTUdmin="U1599" /TUdmin=0 /isTUend="TRUE" CDS complement(2127345..2127683) /gene="arxR" /locus_tag="BSU_19540" /old_locus_tag="BSU19540" /function="16.8: Protect" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:17158660, 18208493, 20652907, 27531959" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 17158660, 18208493, 20652907, 27531959; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional repressor" /protein_id="NP_389835.1" /db_xref="EnsemblGenomes-Gn:BSU19540" /db_xref="EnsemblGenomes-Tr:CAB13845" /db_xref="GOA:O34844" /db_xref="InterPro:IPR002577" /db_xref="InterPro:IPR011991" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="PDB:5HS7" /db_xref="PDB:5HS8" /db_xref="PDB:5HS9" /db_xref="SubtiList:BG13531" /db_xref="UniProtKB/Swiss-Prot:O34844" /translation="MGNTMCPKMESAFSLLGKRWNGLIIHVLMDGPKRFKEITETIPM ISQKMLAERLKELEQNEIVERQVLPETPVKVIYTLTEKGTALQAVFQEMQAWADQFCE PGDTVCEEEK*" gene complement(2127345..2127683) /gene="arxR" /locus_tag="BSU_19540" /old_locus_tag="BSU19540" promotor_-35 2127706..2127713 /Source="Nicolas_upshift_promotors" /id="U1600" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.674325674325674" /psig=1 /xcortree=2349 /SigmaFactorBS="tttcccataagtcttcatcccttcatctatTGATTGACatgt attcaatgaTCCATTACAATAATCTTTCAagttacatttagtaagcttctaacttttc t" /listShort="S754, yodC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2127727..2127746 /Source="Nicolas_upshift_promotors" /id="U1600" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.674325674325674" /psig=1 /xcortree=2349 /SigmaFactorBS="tttcccataagtcttcatcccttcatctatTGATTGACatgt attcaatgaTCCATTACAATAATCTTTCAagttacatttagtaagcttctaacttttc t" /listShort="S754, yodC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2127736 /Source="Nicolas_upshifts" /id="U1600" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.674325674325674" /psig=1 /xcortree=2349 /SigmaFactorBS="tttcccataagtcttcatcccttcatctatTGATTGACatgt attcaatgaTCCATTACAATAATCTTTCAagttacatttagtaagcttctaacttttc t" /listShort="S754, yodC" /GFF_Attribute="listLong" S_feature 2127740..2127812 /Source="Nicolas_S_feature" /locus_tag="new_2127740_2127812" /HighExp="dia5, Diami, dia15, Salt, Lbtran, Heat, HiOs, S1, aero, G180" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S754" promotor_-10 complement(2127771..2127790) /Source="Nicolas_upshift_promotors" /id="U1601" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.882117882117882" /psig="0.997002997002997" /xcortree=3124 /SigmaFactorBS="aaacatccagagtattcgtcatagtgTTTCCTCcttcggata aaCGTGGTATGATAATAGAAAAgttagaagcttactaaatgtaacttgaaagattatt g" /listShort="yodB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2127774) /Source="Nicolas_upshifts" /id="U1601" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.882117882117882" /psig="0.997002997002997" /xcortree=3124 /SigmaFactorBS="aaacatccagagtattcgtcatagtgTTTCCTCcttcggata aaCGTGGTATGATAATAGAAAAgttagaagcttactaaatgtaacttgaaagattatt g" /listShort="yodB" /GFF_Attribute="listLong" promotor_-35 complement(2127802..2127808) /Source="Nicolas_upshift_promotors" /id="U1601" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.882117882117882" /psig="0.997002997002997" /xcortree=3124 /SigmaFactorBS="aaacatccagagtattcgtcatagtgTTTCCTCcttcggata aaCGTGGTATGATAATAGAAAAgttagaagcttactaaatgtaacttgaaagattatt g" /listShort="yodB" /GFF_Attribute="listLong" /label="promotor_-35" CDS 2127813..2128421 /gene="noxC" /locus_tag="BSU_19550" /old_locus_tag="BSU19550" /EC_number="1.6.99.3" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1b: Function from experimental evidences in the studied species; PubMedId: 21749987, 24525333, 26312069; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="water forming NADH oxidase (nitroreductase)" /protein_id="NP_389836.1" /db_xref="EnsemblGenomes-Gn:BSU19550" /db_xref="EnsemblGenomes-Tr:CAB13846" /db_xref="GOA:P81102" /db_xref="InterPro:IPR000415" /db_xref="InterPro:IPR029479" /db_xref="SubtiList:BG13532" /db_xref="UniProtKB/Swiss-Prot:P81102" /translation="MTNTLDVLKARASVKEYDTNAPISKEELTELLDLATKAPSAWNL QHWHFTVFHSDESKAELLPVAYNQKQIVESSAVVAILGDLKANENGEEVYAELASQGY ITDEIKQTLLGQINGAYQSEQFARDSAFLNASLAAMQLMIAAKAKGYDTCAIGGFNKE QFQKQFDISERYVPVMLISIGKAVKPAHQSNRLPLSKVSTWL*" gene 2127813..2128421 /gene="noxC" /locus_tag="BSU_19550" /old_locus_tag="BSU19550" downshifts 2128411 /Source="Nicolas_upshifts" /id="D1077" /incds=0 /nref=98 /ntot=245 /MaxReadThrough="1.58009" /MaxDrop="5.56809" /score="28.8840715" /energy="-14.3" /TU="NA" /idTUdmin="U1600" /TUdmin="-11" /isTUend="TRUE" CDS complement(2128464..2129066) /gene="yodD" /locus_tag="BSU_19560" /old_locus_tag="BSU19560" /EC_number="3.1.-.-" /function="16.11: Scavenge (Catabolism)" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 17407181; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative hydrolase" /protein_id="NP_389837.1" /db_xref="EnsemblGenomes-Gn:BSU19560" /db_xref="EnsemblGenomes-Tr:CAB13847" /db_xref="GOA:O34842" /db_xref="InterPro:IPR002925" /db_xref="InterPro:IPR029058" /db_xref="SubtiList:BG13533" /db_xref="UniProtKB/Swiss-Prot:O34842" /translation="MKHIYEKGTSDNVLLLLHGTGGNEHDLLSLGRFIDPDAHLLGVR GSVLENGMPRFFKRLSEGVFDEKDLVVRTRELKDFIDEAAETHQFNRGRVIAVGYSNG ANIAASLLFHYKDVLKGAILHHPMVPIRGIELPDMAGLPVFIGAGKYDPLCTKEESEE LYRYLRDSGASASVYWQDGGHQLTQHEAEQAREWYKEAIV*" gene complement(2128464..2129066) /gene="yodD" /locus_tag="BSU_19560" /old_locus_tag="BSU19560" CDS complement(2129082..2129993) /gene="yodE" /locus_tag="BSU_19570" /old_locus_tag="BSU19570" /function="16.8: Protect" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 10960106, 17407181, 19329649, 25720121; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative thiol-dependent lyase/dioxygenase" /protein_id="NP_389838.1" /db_xref="EnsemblGenomes-Gn:BSU19570" /db_xref="EnsemblGenomes-Tr:CAB13848" /db_xref="GOA:O34543" /db_xref="InterPro:IPR000595" /db_xref="InterPro:IPR004360" /db_xref="InterPro:IPR029068" /db_xref="SubtiList:BG13534" /db_xref="UniProtKB/Swiss-Prot:O34543" /translation="MKTEGLHHVTAFARDPQENLRFYTEVLGLRLVKKTVNFDDPGTY HFYFGNQNGDPGTIMTFFPFQGSGQGTVGKGQAGRVYFSVPSGSLSFWKERLEKSGLS LEEKTLFGEKGLIFDDTEDLPLAIMEDAKSGKSEWTPDGITTNEAITGMKGVLLYSYD PQATIQLLTESFGYTKVAEEDQIVRLASSAAVGGVIDVHLHPEKRGVGGYGTVHHVAF RTKKKEQAKWLPIIAENHLPSSEILDREYFTSVYFREKGGILFEIATDEPGFMTDETF AELGTSLKLPEWLEKHRQQITDILPEL*" gene complement(2129082..2129993) /gene="yodE" /locus_tag="BSU_19570" /old_locus_tag="BSU19570" promotor_-10 complement(2130022..2130041) /Source="Nicolas_upshift_promotors" /id="U1602" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.317682317682318" /psig="0.997002997002997" /xcortree=3021 /SigmaFactorBS="aaatgattttttcaattatttaatcaaaacacatggTTTGCA tccttttcaataaagGTTTAAAATAATAAATATCTtgaaatcgagataaataggagtg a" /listShort="yodE" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2130038) /Source="Nicolas_upshifts" /id="U1602" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.317682317682318" /psig="0.997002997002997" /xcortree=3021 /SigmaFactorBS="aaatgattttttcaattatttaatcaaaacacatggTTTGCA tccttttcaataaagGTTTAAAATAATAAATATCTtgaaatcgagataaataggagtg a" /listShort="yodE" /GFF_Attribute="listLong" promotor_-35 complement(2130057..2130062) /Source="Nicolas_upshift_promotors" /id="U1602" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.317682317682318" /psig="0.997002997002997" /xcortree=3021 /SigmaFactorBS="aaatgattttttcaattatttaatcaaaacacatggTTTGCA tccttttcaataaagGTTTAAAATAATAAATATCTtgaaatcgagataaataggagtg a" /listShort="yodE" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 2130114..2130117 /Source="Nicolas_upshift_promotors" /id="U1603" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.576423576423576" /psig=1 /xcortree=2907 /SigmaFactorBS="gattaaataattgaaaaaatcatttttttctaataattatCT TGtgatcttttcttacAACTGCTATTATAGTGAGCAttatcatgtttcaggaggaaag t" /listShort="yoyD, yodF" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2130132..2130151 /Source="Nicolas_upshift_promotors" /id="U1603" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.576423576423576" /psig=1 /xcortree=2907 /SigmaFactorBS="gattaaataattgaaaaaatcatttttttctaataattatCT TGtgatcttttcttacAACTGCTATTATAGTGAGCAttatcatgtttcaggaggaaag t" /listShort="yoyD, yodF" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2130134 /Source="Nicolas_upshifts" /id="U1603" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.576423576423576" /psig=1 /xcortree=2907 /SigmaFactorBS="gattaaataattgaaaaaatcatttttttctaataattatCT TGtgatcttttcttacAACTGCTATTATAGTGAGCAttatcatgtttcaggaggaaag t" /listShort="yoyD, yodF" /GFF_Attribute="listLong" CDS 2130177..2130377 /gene="yoyD" /locus_tag="BSU_19579" /old_locus_tag="BSU19579" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 23504016, 24843172; Product type f: factor" /codon_start=1 /transl_table=11 /product="putative exported protein" /protein_id="YP_003097742.1" /db_xref="EnsemblGenomes-Gn:BSU19579" /db_xref="EnsemblGenomes-Tr:CAX52639" /db_xref="GOA:C0H431" /db_xref="InterPro:IPR021741" /db_xref="UniProtKB/Swiss-Prot:C0H431" /translation="MVKKALIVILILLPFVQLALLPLVNRIEPIMFGLPFFHFWLLLW IIVTPLCSFGIYQMQKKDGGLE*" gene 2130177..2130377 /gene="yoyD" /locus_tag="BSU_19579" /old_locus_tag="BSU19579" CDS 2130377..2131867 /gene="yodF" /locus_tag="BSU_19580" /old_locus_tag="BSU19580" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 12823818, 15849754, 16850406, 24142252, 27766092; Product type t : transporter" /codon_start=1 /transl_table=11 /product="putative Na+/metabolite permease" /protein_id="NP_389839.1" /db_xref="EnsemblGenomes-Gn:BSU19580" /db_xref="EnsemblGenomes-Tr:CAB13849" /db_xref="GOA:O34745" /db_xref="InterPro:IPR001734" /db_xref="SubtiList:BG13535" /db_xref="UniProtKB/Swiss-Prot:O34745" /translation="MQGNLTALLITAIIVLTVVCIGFLAGRDKSSRTSVEEWSVGGRR FGGLLVWFLVGADLYTAYTFLGLTSTAFTGGSVAFFAIPYSVLAYFIAYFFLPKLWKV AKIHKLTTLADYARERFNSKLLASLVAIVGVLMLIPYICLQLSGIQDTLQVAGTGYIN VKFVVIISFILVALYTFFSGIKGPTYTAIIKDILVWVIMLFMVVSLPLIHFNGWTPMI DTLVKEAPQMLTIPSEGPKGIPWFITASIVSALALFMWAHAATGVFTAKSADAVRKNS MFLPLYNIVLILVIFLGFIAFLVLPEDTNPRLALLHLIQTSYGGVAQGFAYATIALAS LIPCSIMAIGASNLFANNLYRDLIHPNVSQSKLTLVTRSMVFVVIGLALLFGMLFPTA LVTLQLLGVSGMVQIFPAIAVSLFWKNQTKEATVIGLLAGLAVTFIVYITQSAHGIYE GFWGLAANMIAVVILNPLFVKNAGSNPVIEGLFGKKQDANPNQKGA*" gene 2130377..2131867 /gene="yodF" /locus_tag="BSU_19580" /old_locus_tag="BSU19580" promotor_-10 complement(2131112..2131123) /Source="Nicolas_upshift_promotors" /id="U1604" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=821 /SigmaFactorBS="ttcgccgtgaaaacacctgtagcggcatgtgccCACATAAaa agtgccagagcGGAAACAATAGAtgctgtgataaaccaaggaatgccttttggccctt c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2131116) /Source="Nicolas_upshifts" /id="U1604" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=821 /SigmaFactorBS="ttcgccgtgaaaacacctgtagcggcatgtgccCACATAAaa agtgccagagcGGAAACAATAGAtgctgtgataaaccaaggaatgccttttggccctt c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(2131137..2131143) /Source="Nicolas_upshift_promotors" /id="U1604" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=821 /SigmaFactorBS="ttcgccgtgaaaacacctgtagcggcatgtgccCACATAAaa agtgccagagcGGAAACAATAGAtgctgtgataaaccaaggaatgccttttggccctt c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 2131855 /Source="Nicolas_upshifts" /id="D1078" /incds=0 /nref=128 /ntot=189 /MaxReadThrough="1.75716" /MaxDrop="6.37839" /score="42.3111155" /energy="-14.6" /TU="NA" /idTUdmin="U1603" /TUdmin="-21" /isTUend="TRUE" CDS complement(2131902..2133302) /gene="ctpA" /locus_tag="BSU_19590" /old_locus_tag="BSU19590" /EC_number="3.4.21.102" /function="16.11: Scavenge (Catabolism)" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 8996100, 10974125, 14526016, 17114254, 19889088; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="carboxy-terminal processing protease (Prc homolog, tail specific protease)" /protein_id="NP_389840.1" /db_xref="EnsemblGenomes-Gn:BSU19590" /db_xref="EnsemblGenomes-Tr:CAB13850" /db_xref="GOA:O34666" /db_xref="InterPro:IPR001478" /db_xref="InterPro:IPR002477" /db_xref="InterPro:IPR004447" /db_xref="InterPro:IPR005151" /db_xref="InterPro:IPR029045" /db_xref="InterPro:IPR036034" /db_xref="InterPro:IPR036365" /db_xref="InterPro:IPR036366" /db_xref="SubtiList:BG11794" /db_xref="UniProtKB/Swiss-Prot:O34666" /translation="MKRQLKLFFIVLITAVVASALTLFITGNSSILGQKSASTGDSKF DKLNKAYEQIKSDYYQKTDDDKLVDGAIKGMIQSLDDPYSTYMDQEQAKSFDETISAS FEGIGAQVEEKDGEILIVSPIKGSPAEKAGIKPRDQIIKVNGKSVKGMNVNEAVALIR GKKGTKVKLELNRAGVGNIDLSIKRDTIPVETVYSEMKDNNIGEIQITSFSETTAKEL TDAIDSLEKKGAKGYILDLRGNPGGLMEQAITMSNLFIDKGKNIMQVEYKNGSKEVMK AEKERKVTKPTVVLVNDGTASAAEIMAAALHESSNVPLIGETTFGKGTVQTAKEYDDG STVKLTVAKWLTADGEWIHKKGIKPQVKAELPDYAKLPYLDADKTYKSGDTGTNVKVA QKMLKALGYKVKVNSMYDQDFVSVVKQFQKKEKLNETGILTGDTTTKLMIELQKKLSD NDTQMEKAIETLKKEM*" gene complement(2131902..2133302) /gene="ctpA" /locus_tag="BSU_19590" /old_locus_tag="BSU19590" downshifts complement(2131926) /Source="Nicolas_upshifts" /id="D1079" /incds=0 /nref=188 /ntot=292 /MaxReadThrough="0.590400000000001" /MaxDrop="7.62713" /score="34.5981085" /energy="-14.6" /TU="NA" /idTUdmin="U1606" /TUdmin="-18" /isTUend="TRUE" promotor_-35 2133073..2133082 /Source="Nicolas_upshift_promotors" /id="U1605" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp="0.992007992007992" /psig="0.992007992007992" /xcortree=383 /SigmaFactorBS="tgtagaatacggatcatccagtgatTGAATCATTCctttaat tgctCCGTCTACTAATTTGTcatcatctgttttttggtaataatcacttttgatttgc t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2133094..2133109 /Source="Nicolas_upshift_promotors" /id="U1605" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp="0.992007992007992" /psig="0.992007992007992" /xcortree=383 /SigmaFactorBS="tgtagaatacggatcatccagtgatTGAATCATTCctttaat tgctCCGTCTACTAATTTGTcatcatctgttttttggtaataatcacttttgatttgc t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2133108 /Source="Nicolas_upshifts" /id="U1605" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp="0.992007992007992" /psig="0.992007992007992" /xcortree=383 /SigmaFactorBS="tgtagaatacggatcatccagtgatTGAATCATTCctttaat tgctCCGTCTACTAATTTGTcatcatctgttttttggtaataatcacttttgatttgc t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 complement(2133322..2133341) /Source="Nicolas_upshift_promotors" /id="U1606" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.878121878121878" /psig=1 /xcortree=3142 /SigmaFactorBS="gaaaagcaaaagaagggcgtttctctttcatttctgctccGA GTTGACgaataagaattcgTCCATGATAATAATGTAAGAagaaaaaggtggtgtttaa t" /listShort="ctpA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2133342) /Source="Nicolas_upshifts" /id="U1606" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.878121878121878" /psig=1 /xcortree=3142 /SigmaFactorBS="gaaaagcaaaagaagggcgtttctctttcatttctgctccGA GTTGACgaataagaattcgTCCATGATAATAATGTAAGAagaaaaaggtggtgtttaa t" /listShort="ctpA" /GFF_Attribute="listLong" promotor_-35 complement(2133355..2133362) /Source="Nicolas_upshift_promotors" /id="U1606" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.878121878121878" /psig=1 /xcortree=3142 /SigmaFactorBS="gaaaagcaaaagaagggcgtttctctttcatttctgctccGA GTTGACgaataagaattcgTCCATGATAATAATGTAAGAagaaaaaggtggtgtttaa t" /listShort="ctpA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 2133401..2133410 /Source="Nicolas_upshift_promotors" /id="U1607" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp="0.995004995004995" /psig="0.995004995004995" /xcortree=1327 /SigmaFactorBS="tcaactcggagcagaaatgaaagagaaacgcccttcttttgc tttTCATAAACCTatgtctttatacGACATATGATAAGGAAAAAGgaggattcgatat t" /listShort="yodH, yodI" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 2133416 /Source="Nicolas_upshifts" /id="U1607" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp="0.995004995004995" /psig="0.995004995004995" /xcortree=1327 /SigmaFactorBS="tcaactcggagcagaaatgaaagagaaacgcccttcttttgc tttTCATAAACCTatgtctttatacGACATATGATAAGGAAAAAGgaggattcgatat t" /listShort="yodH, yodI" /GFF_Attribute="listLong" promotor_-10 2133423..2133442 /Source="Nicolas_upshift_promotors" /id="U1607" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp="0.995004995004995" /psig="0.995004995004995" /xcortree=1327 /SigmaFactorBS="tcaactcggagcagaaatgaaagagaaacgcccttcttttgc tttTCATAAACCTatgtctttatacGACATATGATAAGGAAAAAGgaggattcgatat t" /listShort="yodH, yodI" /GFF_Attribute="listLong" /label="promotor_-10" CDS 2133455..2134156 /gene="yodH" /locus_tag="BSU_19600" /old_locus_tag="BSU19600" /EC_number="2.1.1.-" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 19703276; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative S-adenosylmethionine-dependent methyltransferase" /protein_id="NP_389841.1" /db_xref="EnsemblGenomes-Gn:BSU19600" /db_xref="EnsemblGenomes-Tr:CAB13851" /db_xref="GOA:O34954" /db_xref="InterPro:IPR013216" /db_xref="InterPro:IPR029063" /db_xref="SubtiList:BG13536" /db_xref="UniProtKB/Swiss-Prot:O34954" /translation="MSRYLEMLSLFGVAGAHPGGLAFSKAVLQKAAPSPDQPILDAGC GTGQTAAYLGHLLYPVTVVDKDPIMLEKAKKRFANEGLAIPAYQAELEHLPFSSESFS CVLSESVLSFSRLTSSLQEISRVLKPSGMLIGIEAALKKPMPPAEKKQMMDFYGFTCL HEESEWHKLLRSYGFQKTEAMSLLPEDMEFEPTTEMDLSQTIDPIYYDTLQTHYQLMQ LYSEYMGHCIFIAYK*" gene 2133455..2134156 /gene="yodH" /locus_tag="BSU_19600" /old_locus_tag="BSU19600" promotor_-35 2134181..2134189 /Source="Nicolas_upshift_promotors" /id="U1608" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.996003996003996" /psig="0.996003996003996" /xcortree=1407 /SigmaFactorBS="tacaagtaaaacggcgtatcgccccctgttttcGTCCAACCT ttttttcctatctATCATATGCTGATAGAAAGTcaggataggaggggaacaatattgg a" /listShort="yodI" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2134203..2134222 /Source="Nicolas_upshift_promotors" /id="U1608" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.996003996003996" /psig="0.996003996003996" /xcortree=1407 /SigmaFactorBS="tacaagtaaaacggcgtatcgccccctgttttcGTCCAACCT ttttttcctatctATCATATGCTGATAGAAAGTcaggataggaggggaacaatattgg a" /listShort="yodI" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2134208 /Source="Nicolas_upshifts" /id="U1608" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.996003996003996" /psig="0.996003996003996" /xcortree=1407 /SigmaFactorBS="tacaagtaaaacggcgtatcgccccctgttttcGTCCAACCT ttttttcctatctATCATATGCTGATAGAAAGTcaggataggaggggaacaatattgg a" /listShort="yodI" /GFF_Attribute="listLong" CDS 2134244..2134495 /gene="yodI" /locus_tag="BSU_19610" /old_locus_tag="BSU19610" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 12562816, 22882546, 23155385; Product type s: structure" /codon_start=1 /transl_table=11 /product="putative spore coat protein" /protein_id="NP_389842.1" /db_xref="EnsemblGenomes-Gn:BSU19610" /db_xref="EnsemblGenomes-Tr:CAB13852" /db_xref="GOA:O34654" /db_xref="SubtiList:BG13537" /db_xref="UniProtKB/Swiss-Prot:O34654" /translation="MERYYHLCKNHQGKVVRITERGGRVHVGRITRVTRDRVFIAPVG GGPRGFGYGYWGGYWGYGAAYGISLGLIAGVALAGLFFW*" gene 2134244..2134495 /gene="yodI" /locus_tag="BSU_19610" /old_locus_tag="BSU19610" downshifts 2134516 /Source="Nicolas_upshifts" /id="D1080" /incds=0 /nref=49 /ntot=83 /MaxReadThrough="0.88268" /MaxDrop="7.18785" /score="13.9812819" /energy="-15.5" /TU="NA" /idTUdmin="U1607" /TUdmin=0 /isTUend="TRUE" CDS complement(2134566..2135387) /gene="ldcB" /locus_tag="BSU_19620" /old_locus_tag="BSU19620" /EC_number="3.4.16.4" /function="16.6: Maintain" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:8631706, 15187182, 24909784" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8631706, 15187182, 24909784; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="D-alanyl-D-alanine carboxypeptidase lipoprotein (D-ala releasing from tetrapeptide hydrolysis)" /protein_id="NP_389843.1" /db_xref="EnsemblGenomes-Gn:BSU19620" /db_xref="EnsemblGenomes-Tr:CAB13853" /db_xref="GOA:O34866" /db_xref="InterPro:IPR003709" /db_xref="InterPro:IPR009045" /db_xref="PDB:4OX3" /db_xref="SubtiList:BG13538" /db_xref="UniProtKB/Swiss-Prot:O34866" /translation="MKKSGKWFSLAAALSVTAIVGAGCSMSNGDAQKDTKTTAETKQT EQKTADSKKSNTQNSEFSLESQYFNDIKKVDGLETIQNPENILALVNKQYALPGNYEP SDLVIPDVEFSFEEKIQKRYIRKEAADALKTMFDAAKKEGYELAAVSGYRSYDRQKVI FDNEVSLKGERKAKEAVAYPGESEHQTGLAMDISSRSNGFELNEAFGSTADGKWVQDN AYKYGFIIRYPKNKEDITKYEYEPWHLRYVGKKAAKVIQDNDLTLEEYFEKVKKI*" gene complement(2134566..2135387) /gene="ldcB" /locus_tag="BSU_19620" /old_locus_tag="BSU19620" downshifts complement(2134592) /Source="Nicolas_upshifts" /id="D1081" /incds=0 /nref=180 /ntot=242 /MaxReadThrough="0.784690000000001" /MaxDrop="5.88637" /score="-9.13236272" /energy="-6.1" /TU="NA" /idTUdmin="U1609" /TUdmin=0 /isTUend="TRUE" S_feature complement(2135388..2135469) /Source="Nicolas_S_feature" /locus_tag="new_2135388_2135469_c" /HighExp="dia15, LBGexp, G180, LBGtran, dia0, H2O2, Oxctl, Lbexp, Paraq, G135" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S755" CDS complement(2135470..2136171) /gene="deoD" /locus_tag="BSU_19630" /old_locus_tag="BSU19630" /EC_number="2.4.2.1" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:12571059, 16511068, 21279421, 21424839" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12571059, 16511068, 21279421, 21424839; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="purine nucleoside phosphorylase" /protein_id="NP_389844.1" /db_xref="EnsemblGenomes-Gn:BSU19630" /db_xref="EnsemblGenomes-Tr:CAB13854" /db_xref="GOA:O34925" /db_xref="InterPro:IPR000845" /db_xref="InterPro:IPR004402" /db_xref="InterPro:IPR018016" /db_xref="InterPro:IPR035994" /db_xref="PDB:4D8V" /db_xref="PDB:4D8X" /db_xref="PDB:4D8Y" /db_xref="PDB:4D98" /db_xref="PDB:4D9H" /db_xref="PDB:4DA0" /db_xref="PDB:4DA6" /db_xref="PDB:4DA7" /db_xref="PDB:4DA8" /db_xref="PDB:4DAB" /db_xref="PDB:4DAE" /db_xref="PDB:4DAN" /db_xref="PDB:4DAO" /db_xref="PDB:4DAR" /db_xref="SubtiList:BG12581" /db_xref="UniProtKB/Swiss-Prot:O34925" /translation="MSVHIGAEKGQIADTVLLPGDPLRAKFIAETYLENVECYNEVRG MYGFTGTYKGKKISVQGTGMGVPSISIYVNELIQSYDVQNLIRVGSCGAIRKDVKVRD VILAMTSSTDSQMNRVAFGSVDFAPCADFELLKNAYDAAKDKGVPVTVGSVFTADQFY NDDSQIEKLAKYGVLGVEMETTALYTLAAKHGRKALSILTVSDHVLTGEETTAEERQT TFHDMIEVALHSVSQ*" gene complement(2135470..2136171) /gene="deoD" /locus_tag="BSU_19630" /old_locus_tag="BSU19630" S_feature complement(2136172..2136261) /Source="Nicolas_S_feature" /locus_tag="new_2136172_2136261_c" /HighExp="dia15, G180, dia5, LBGtran, dia0, LBGexp, Lbexp, G150, Oxctl, H2O2" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S756" promotor_-10 complement(2136246..2136265) /Source="Nicolas_upshift_promotors" /id="U1609" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.65034965034965" /psig="0.999000999001" /xcortree=2571 /SigmaFactorBS="ccgtttttctgaggaagtgcctaacagatcctcgaaCATTTc ttttttcgatatatTCCTTTATAATCAATGCTGAagtttgtttcatcatgacattcgt t" /listShort="S756, deoD, S755, yodJ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2136261) /Source="Nicolas_upshifts" /id="U1609" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.65034965034965" /psig="0.999000999001" /xcortree=2571 /SigmaFactorBS="ccgtttttctgaggaagtgcctaacagatcctcgaaCATTTc ttttttcgatatatTCCTTTATAATCAATGCTGAagtttgtttcatcatgacattcgt t" /listShort="S756, deoD, S755, yodJ" /GFF_Attribute="listLong" promotor_-35 complement(2136281..2136285) /Source="Nicolas_upshift_promotors" /id="U1609" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.65034965034965" /psig="0.999000999001" /xcortree=2571 /SigmaFactorBS="ccgtttttctgaggaagtgcctaacagatcctcgaaCATTTc ttttttcgatatatTCCTTTATAATCAATGCTGAagtttgtttcatcatgacattcgt t" /listShort="S756, deoD, S755, yodJ" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 2136319..2136325 /Source="Nicolas_upshift_promotors" /id="U1610" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=862 /SigmaFactorBS="gttaggcacttcctcagaaaaaCGGATAAtcggggtgttaat tTGAAAACCTAACcgcaggaaggaggggtgggacatgggtaaaaaacatcgtaaccgg a" /listShort="yoyE" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2136340..2136351 /Source="Nicolas_upshift_promotors" /id="U1610" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=862 /SigmaFactorBS="gttaggcacttcctcagaaaaaCGGATAAtcggggtgttaat tTGAAAACCTAACcgcaggaaggaggggtgggacatgggtaaaaaacatcgtaaccgg a" /listShort="yoyE" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2136357 /Source="Nicolas_upshifts" /id="U1610" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=862 /SigmaFactorBS="gttaggcacttcctcagaaaaaCGGATAAtcggggtgttaat tTGAAAACCTAACcgcaggaaggaggggtgggacatgggtaaaaaacatcgtaaccgg a" /listShort="yoyE" /GFF_Attribute="listLong" CDS 2136373..2136498 /gene="yoyE" /locus_tag="BSU_19639" /old_locus_tag="BSU19639" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 24079885" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="YP_003097743.1" /db_xref="EnsemblGenomes-Gn:BSU19639" /db_xref="EnsemblGenomes-Tr:CAX52640" /db_xref="UniProtKB/Swiss-Prot:C0H432" /translation="MGKKHRNRITGQKKNNHIPEKDIIAAEEAHGKEYSAAKRKP*" gene 2136373..2136498 /gene="yoyE" /locus_tag="BSU_19639" /old_locus_tag="BSU19639" downshifts 2136496 /Source="Nicolas_upshifts" /id="D1082" /incds=0 /nref=9 /ntot=26 /MaxReadThrough="0.67198" /MaxDrop="4.89617" /score="16.4028635" /energy="-8.5" /TU="NA" /idTUdmin="U1610" /TUdmin=0 /isTUend="TRUE" CDS complement(2136538..2136852) /gene="yodL" /locus_tag="BSU_19640" /old_locus_tag="BSU19640" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:24079885, 27215790" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 24079885, 27215790; Product type f: factor" /codon_start=1 /transl_table=11 /product="shape determination factor" /protein_id="NP_389845.2" /db_xref="EnsemblGenomes-Gn:BSU19640" /db_xref="EnsemblGenomes-Tr:CAB13855" /db_xref="InterPro:IPR025923" /db_xref="SubtiList:BG13539" /db_xref="UniProtKB/Swiss-Prot:O30472" /translation="MMLSVFKKKSCSYDVTIFQTPRFGEKKGYRAVYRTELNGSDHQD VLKRAFSLFNVFDTVPSDYDARFMATGDVILIDEGRKGKTYYQLLPAGWRKINRLIVQ TT*" gene complement(2136538..2136852) /gene="yodL" /locus_tag="BSU_19640" /old_locus_tag="BSU19640" downshifts complement(2136550) /Source="Nicolas_upshifts" /id="D1083" /incds=0 /nref=96 /ntot=232 /MaxReadThrough="1.74792" /MaxDrop="5.79235" /score="-0.334745097" /energy="-8.5" /TU="NA" /idTUdmin="U1611" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(2136873..2136891) /Source="Nicolas_upshift_promotors" /id="U1611" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=447 /SigmaFactorBS="aaagattaagcggtttcgacaaaaatagagAGAGGAAAAcac agcaaaaACGCCAATATGTTAAAGAAataaaagggaggggatcttgatgatgttatcc g" /listShort="yodL" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2136880) /Source="Nicolas_upshifts" /id="U1611" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=447 /SigmaFactorBS="aaagattaagcggtttcgacaaaaatagagAGAGGAAAAcac agcaaaaACGCCAATATGTTAAAGAAataaaagggaggggatcttgatgatgttatcc g" /listShort="yodL" /GFF_Attribute="listLong" promotor_-35 complement(2136902..2136910) /Source="Nicolas_upshift_promotors" /id="U1611" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=447 /SigmaFactorBS="aaagattaagcggtttcgacaaaaatagagAGAGGAAAAcac agcaaaaACGCCAATATGTTAAAGAAataaaagggaggggatcttgatgatgttatcc g" /listShort="yodL" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2136913..2137524) /gene="pgpB" /locus_tag="BSU_19650" /old_locus_tag="BSU19650" /EC_number="3.1.3.27" /EC_number="3.1.3.-" /function="16.6: Maintain" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:15849754, 16850406, 27528508, 28168443" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15849754, 16850406, 27528508, 28168443; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="phosphatidylglycerol phosphate (PGP) phosphatase; undecaprenyl-pyrophosphate phosphatase (promiscuous activity)" /protein_id="NP_389846.1" /db_xref="EnsemblGenomes-Gn:BSU19650" /db_xref="EnsemblGenomes-Tr:CAB13856" /db_xref="GOA:O34349" /db_xref="InterPro:IPR000326" /db_xref="InterPro:IPR036938" /db_xref="PDB:5JKI" /db_xref="SubtiList:BG13540" /db_xref="UniProtKB/Swiss-Prot:O34349" /translation="MYKPVSLFLFFLILAAAIHTNAVQSADEAISKAAVLIRQPWLNE VMTGITHLGASSFLLPLIVIIGAGMFFYRKTWDGLLMLLVFGTDRLLNKVLKEWIERV RPDFAPLVHESSFSFPSGHSMNAACVYPVIAYFLVKHLPFLSKHKKMVYIIAGVIAVL VGISRVYLGVHFVTDVLGGFSLGLLLFFLVKGFDEKIKRFRQK*" gene complement(2136913..2137524) /gene="pgpB" /locus_tag="BSU_19650" /old_locus_tag="BSU19650" CDS complement(2137602..2137778) /gene="yozD" /locus_tag="BSU_19660" /old_locus_tag="BSU19660" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_389847.1" /db_xref="EnsemblGenomes-Gn:BSU19660" /db_xref="EnsemblGenomes-Tr:CAB13857" /db_xref="InterPro:IPR025545" /db_xref="SubtiList:BG13751" /db_xref="UniProtKB/Swiss-Prot:O31863" /translation="MKEIDLVIDTEEIAEFFYRELARRGYIPSEDELFEIADITFDYL IEKCMIDEELDEDE*" gene complement(2137602..2137778) /gene="yozD" /locus_tag="BSU_19660" /old_locus_tag="BSU19660" downshifts complement(2137606) /Source="Nicolas_upshifts" /id="D1084" /incds=0 /nref=35 /ntot=48 /MaxReadThrough="3.33111" /MaxDrop="5.99901" /score="19.8458751" /energy="-11.9" /TU="U1612,U1613" /idTUdmin="U1615" /TUdmin=0 /isTUend="TRUE" upshifts complement(2137617) /Source="Nicolas_upshifts" /id="U1612" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.51048951048951" /psig="0.934065934065934" /xcortree=2494 /SigmaFactorBS="tgaaatcgctgatattacCTTTgattatttgatagaaAAATG TATGATAGATGAAGAgctggatgaagatgagtgaggcttaaaaccggagcggtcagct c" /listShort="yodM, yodL" /GFF_Attribute="listLong" promotor_-10 complement(2137621..2137640) /Source="Nicolas_upshift_promotors" /id="U1612" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.51048951048951" /psig="0.934065934065934" /xcortree=2494 /SigmaFactorBS="tgaaatcgctgatattacCTTTgattatttgatagaaAAATG TATGATAGATGAAGAgctggatgaagatgagtgaggcttaaaaccggagcggtcagct c" /listShort="yodM, yodL" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 complement(2137656..2137659) /Source="Nicolas_upshift_promotors" /id="U1612" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.51048951048951" /psig="0.934065934065934" /xcortree=2494 /SigmaFactorBS="tgaaatcgctgatattacCTTTgattatttgatagaaAAATG TATGATAGATGAAGAgctggatgaagatgagtgaggcttaaaaccggagcggtcagct c" /listShort="yodM, yodL" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(2137792..2137810) /Source="Nicolas_upshift_promotors" /id="U1613" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1118 /SigmaFactorBS="tttttattcaatatatgactgaaagaattgtttagaacaccg GGTATAattcagcctgtttttTCATAAAACATAAAAAAGGaggcggtacggagatgaa a" /listShort="yozD, yodM" /listLong="yodL" /label="promotor_-10" upshifts complement(2137813) /Source="Nicolas_upshifts" /id="U1613" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1118 /SigmaFactorBS="tttttattcaatatatgactgaaagaattgtttagaacaccg GGTATAattcagcctgtttttTCATAAAACATAAAAAAGGaggcggtacggagatgaa a" /listShort="yozD, yodM" /listLong="yodL" S_feature complement(2137815..2138036) /Source="Nicolas_S_feature" /locus_tag="new_2137815_2138036_c" /HighExp="S8, S7, S6, BT, B36, Pyr, G/S, H2O2, S5, G135" /AntisenseName="yoyF" /AntisenseCor="0.43167183745996701" /AntisenseRegPval="-12.9" /CDS_PredictionProba="NA" /TUshortSig="SigK" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S757" promotor_-35 complement(2137826..2137831) /Source="Nicolas_upshift_promotors" /id="U1613" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1118 /SigmaFactorBS="tttttattcaatatatgactgaaagaattgtttagaacaccg GGTATAattcagcctgtttttTCATAAAACATAAAAAAGGaggcggtacggagatgaa a" /listShort="yozD, yodM" /listLong="yodL" /label="promotor_-35" promotor_-35 2137836..2137841 /Source="Nicolas_upshift_promotors" /id="U1614" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=997 /SigmaFactorBS="ttatgttttatgaaaaaacaggctgaattatacccggtGTTC TAaacaattctttcagTCATATATTGAATAAAAAAcgagccatgggaggctgacgcta t" /listShort="yoyF, S758" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2137856..2137874 /Source="Nicolas_upshift_promotors" /id="U1614" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=997 /SigmaFactorBS="ttatgttttatgaaaaaacaggctgaattatacccggtGTTC TAaacaattctttcagTCATATATTGAATAAAAAAcgagccatgggaggctgacgcta t" /listShort="yoyF, S758" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2137858 /Source="Nicolas_upshifts" /id="U1614" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=997 /SigmaFactorBS="ttatgttttatgaaaaaacaggctgaattatacccggtGTTC TAaacaattctttcagTCATATATTGAATAAAAAAcgagccatgggaggctgacgcta t" /listShort="yoyF, S758" /GFF_Attribute="listLong" CDS 2137897..2138040 /gene="yoyF" /locus_tag="BSU_19669" /old_locus_tag="BSU19669" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_003097744.1" /db_xref="EnsemblGenomes-Gn:BSU19669" /db_xref="EnsemblGenomes-Tr:CAX52641" /db_xref="GOA:C0H433" /db_xref="UniProtKB/Swiss-Prot:C0H433" /translation="MIAKMMEALDGERFDIIMEKTLKGMTRVMIWGCLPYFLYVLIRM FTN*" gene 2137897..2138040 /gene="yoyF" /locus_tag="BSU_19669" /old_locus_tag="BSU19669" CDS complement(2138037..2138717) /gene="yodN" /locus_tag="BSU_19670" /old_locus_tag="BSU19670" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_389848.1" /db_xref="EnsemblGenomes-Gn:BSU19670" /db_xref="EnsemblGenomes-Tr:CAB13858" /db_xref="SubtiList:BG13541" /db_xref="UniProtKB/Swiss-Prot:O34414" /translation="MKQNKPKFQVGDIVVVIMYGTVGTITKVHQIDKHYLYEVNHNEV LYFESSIQLYKDYEGVIVDMEKLDIEYEFLIGDVVYVKDYGKELFRIIGHRTEIWRYL EDGWEDIIYELTRLKDGEWLETEEEDLTLVLRKYEMDQFVHQLLFVHYVGETGHEIGE DIASSALLQFEGGDEDQDTLHILAVSIVDELLDIYNDYKILYEMFQDEEYKDMMMFVL ESLKEHFS*" gene complement(2138037..2138717) /gene="yodN" /locus_tag="BSU_19670" /old_locus_tag="BSU19670" S_feature 2138041..2139052 /Source="Nicolas_S_feature" /locus_tag="new_2138041_2139052" /HighExp="LoTm, S3, S8, S7, S4, T5.0H, BT, T4.0H, Pyr, S6" /AntisenseName="yodN" /AntisenseCor="0.52628108909126403" /AntisenseRegPval="-19.8" /CDS_PredictionProba="NA" /TUshortSig="SigEF" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S758" promotor_-10 complement(2138744..2138763) /Source="Nicolas_upshift_promotors" /id="U1615" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1356 /SigmaFactorBS="ttggatatttcctttggttttcatGCCCATGCGAattggctt cacccGGCATACGATAGCGTATGAGaaatgttgcggcgagggggagacaccatgaagc a" /listShort="yodN, S757, yozD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2138750) /Source="Nicolas_upshifts" /id="U1615" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1356 /SigmaFactorBS="ttggatatttcctttggttttcatGCCCATGCGAattggctt cacccGGCATACGATAGCGTATGAGaaatgttgcggcgagggggagacaccatgaagc a" /listShort="yodN, S757, yozD" /GFF_Attribute="listLong" promotor_-35 complement(2138777..2138786) /Source="Nicolas_upshift_promotors" /id="U1615" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1356 /SigmaFactorBS="ttggatatttcctttggttttcatGCCCATGCGAattggctt cacccGGCATACGATAGCGTATGAGaaatgttgcggcgagggggagacaccatgaagc a" /listShort="yodN, S757, yozD" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2138868..2139092) /gene="yozE" /locus_tag="BSU_19680" /old_locus_tag="BSU19680" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 22843344" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_389849.1" /db_xref="EnsemblGenomes-Gn:BSU19680" /db_xref="EnsemblGenomes-Tr:CAB13859" /db_xref="InterPro:IPR010673" /db_xref="InterPro:IPR023089" /db_xref="InterPro:IPR036806" /db_xref="PDB:2FJ6" /db_xref="SubtiList:BG13752" /db_xref="UniProtKB/Swiss-Prot:O31864" /translation="MKSFYHYLLKYRHPKPKDSISEFANQAYEDHSFPKTSTDYHEIS SYLELNADYLHTMATFDEAWDQYESEVHGR*" gene complement(2138868..2139092) /gene="yozE" /locus_tag="BSU_19680" /old_locus_tag="BSU19680" downshifts complement(2138882) /Source="Nicolas_upshifts" /id="D1085" /incds=0 /nref=115 /ntot=243 /MaxReadThrough="1.81033" /MaxDrop="7.07662" /score="34.0666929" /energy="-10.8" /TU="NA" /idTUdmin="U1616" /TUdmin=0 /isTUend="TRUE" misc_feature complement(2139133..2139152) /Source="Nicolas_upshift_promotors" /id="U1616" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.619380619380619" /psig="0.983016983016983" /xcortree=637 /SigmaFactorBS="aaacgcaactattttgacttctcctgagtcatgtttcagtat tcttttgttgtAATTTTACACTTGAACTGTAtaatagaacaacaaaagacagacatca g" /listShort="yozE" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(2139145) /Source="Nicolas_upshifts" /id="U1616" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.619380619380619" /psig="0.983016983016983" /xcortree=637 /SigmaFactorBS="aaacgcaactattttgacttctcctgagtcatgtttcagtat tcttttgttgtAATTTTACACTTGAACTGTAtaatagaacaacaaaagacagacatca g" /listShort="yozE" /GFF_Attribute="listLong" CDS complement(2139179..2139457) /gene="yokU" /locus_tag="BSU_19689" /old_locus_tag="BSU19689" /function="18: Unknown function" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 22843344, 24914178" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="YP_003097745.1" /db_xref="EnsemblGenomes-Gn:BSU19689" /db_xref="EnsemblGenomes-Tr:CAX52642" /db_xref="InterPro:IPR022451" /db_xref="InterPro:IPR022453" /db_xref="UniProtKB/Swiss-Prot:C0H434" /translation="MKTCEWCGELEAVPGRNTVYWELPDGTRAIELTDTPAMVCSSCG MTYQEENTVKEIEDQLLLIQTKKLPESLTYQQLMETERILKRNYFDFS*" gene complement(2139179..2139457) /gene="yokU" /locus_tag="BSU_19689" /old_locus_tag="BSU19689" CDS complement(2139454..2140869) /gene="kamA" /locus_tag="BSU_19690" /old_locus_tag="BSU19690" /EC_number="5.4.3.2" /function="16.11: Scavenge (Catabolism)" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:10629195, 10839984, 11148055, 17254853, 18307109, 21538109" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10629195, 10839984, 11148055, 17254853, 18307109, 21538109; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="lysine 2,3-aminomutase" /protein_id="NP_389850.1" /db_xref="EnsemblGenomes-Gn:BSU19690" /db_xref="EnsemblGenomes-Tr:CAB13860" /db_xref="GOA:O34676" /db_xref="InterPro:IPR003739" /db_xref="InterPro:IPR007197" /db_xref="InterPro:IPR013785" /db_xref="InterPro:IPR022459" /db_xref="InterPro:IPR025895" /db_xref="SubtiList:BG13542" /db_xref="UniProtKB/Swiss-Prot:O34676" /translation="MKNKWYKPKRHWKEIELWKDVPEEKWNDWLWQLTHTVRTLDDLK KVINLTEDEEEGVRISTKTIPLNITPYYASLMDPDNPRCPVRMQSVPLSEEMHKTKYD LEDPLHEDEDSPVPGLTHRYPDRVLFLVTNQCSMYCRYCTRRRFSGQIGMGVPKKQLD AAIAYIRETPEIRDCLISGGDGLLINDQILEYILKELRSIPHLEVIRIGTRAPVVFPQ RITDHLCEILKKYHPVWLNTHFNTSIEMTEESVEACEKLVNAGVPVGNQAVVLAGIND SVPIMKKLMHDLVKIRVRPYYIYQCDLSEGIGHFRAPVSKGLEIIEGLRGHTSGYAVP TFVVDAPGGGGKIALQPNYVLSQSPDKVILRNFEGVITSYPEPENYIPNQADAYFESV FPETADKKEPIGLSAIFADKEVSFTPENVDRIKRREAYIANPEHETLKDRREKRDQLK EKKFLAQQKKQKETECGGDSS*" gene complement(2139454..2140869) /gene="kamA" /locus_tag="BSU_19690" /old_locus_tag="BSU19690" promotor_-35 2140125..2140128 /Source="Nicolas_upshift_promotors" /id="U1617" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.68031968031968" /psig="0.995004995004995" /xcortree=2431 /SigmaFactorBS="ccgcgttcaccagcttttcacatgcctcaacggattCTTCtg tcatttcgatgctTGTGTTAAAATGGGTGTTCAgccagaccggatgatattttttcaa t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2140144..2140163 /Source="Nicolas_upshift_promotors" /id="U1617" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.68031968031968" /psig="0.995004995004995" /xcortree=2431 /SigmaFactorBS="ccgcgttcaccagcttttcacatgcctcaacggattCTTCtg tcatttcgatgctTGTGTTAAAATGGGTGTTCAgccagaccggatgatattttttcaa t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2140149 /Source="Nicolas_upshifts" /id="U1617" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.68031968031968" /psig="0.995004995004995" /xcortree=2431 /SigmaFactorBS="ccgcgttcaccagcttttcacatgcctcaacggattCTTCtg tcatttcgatgctTGTGTTAAAATGGGTGTTCAgccagaccggatgatattttttcaa t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" CDS complement(2140898..2141725) /gene="kamB" /locus_tag="BSU_19700" /old_locus_tag="BSU19700" /EC_number="2.3.1.-" /function="16.8: Protect" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:21538109, 24914178" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 21538109, 24914178; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="epsilon-amino-beta-lysine acetyl transferase" /protein_id="NP_389851.1" /db_xref="EnsemblGenomes-Gn:BSU19700" /db_xref="EnsemblGenomes-Tr:CAB13861" /db_xref="GOA:O34895" /db_xref="InterPro:IPR000182" /db_xref="InterPro:IPR016181" /db_xref="InterPro:IPR022525" /db_xref="InterPro:IPR029025" /db_xref="SubtiList:BG13543" /db_xref="UniProtKB/Swiss-Prot:O34895" /translation="MLKSIKSSGVTAVLDHDGFNKRIRVVRYDGAIEKALPDIVAAAK EENAEKIIVYAKQHDEPILAKQLFAPEGYLKGYYLGHSACVMVRYLSESRRQTDSYTE EQEIIEAIYRTAPRLRNDSTPVFTMRKAETNDMYQLSMLYKKVFRTYPTPVFDPAYIE KTMNANTVYYIMLDHDRLISAASAEINPELGHAEITDCAVLPEYRGHSLTSFLIEALE KEMAGEDIVHVFSLARASSFGMNAVLYHSGYQYGGRLINNCFIAEGLENMNIWCKQL* " gene complement(2140898..2141725) /gene="kamB" /locus_tag="BSU_19700" /old_locus_tag="BSU19700" CDS complement(2141703..2143013) /gene="yodQ" /locus_tag="BSU_19710" /old_locus_tag="BSU19710" /EC_number="3.5.1.-" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 23944997, 28032445; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative deacetylase" /protein_id="NP_389852.1" /db_xref="EnsemblGenomes-Gn:BSU19710" /db_xref="EnsemblGenomes-Tr:CAB13862" /db_xref="GOA:O34984" /db_xref="InterPro:IPR002933" /db_xref="InterPro:IPR010182" /db_xref="InterPro:IPR011650" /db_xref="InterPro:IPR033687" /db_xref="InterPro:IPR036264" /db_xref="SubtiList:BG12569" /db_xref="UniProtKB/Swiss-Prot:O34984" /translation="MRMQDIERKVIEWLDQHSAKAIRLLKRLIGEKSTLGSEFNAQAV VLEKLRQFHMDIDVWEPSIKQLKQHPYFKSNRSDFHESPNIVAKKTGAGGGRSLILNG HIDVVPEGSVKDWKYEPYQAVEENGKIYGRGSTDMKGGNTALLFALEALHACDVKLKG DVLFQSVVDEECGGAGTLSAIMRGYRADGALIPEPTNMKLFIKQQGSMWFRITVKGLS AHGGTRYEGVSAIEKSMHVITAIQELEKVRNARISDPLYDNIPIPVPVNIGTISGGAW PSSVADRVVIEGRCGIAPHEKPEAVKLELENWLKDLEYHDEWFKRHPVQVEWFGAQWL PNDLPDDHPLISVLQSAYQKMKQTEPIIEASPWGTDGGLLYHAGDTPVIVFGPGETKT AHQANEYIEVEAMIESAKIIALFVMDWCGLHTDGEDADAQVNKE*" gene complement(2141703..2143013) /gene="yodQ" /locus_tag="BSU_19710" /old_locus_tag="BSU19710" CDS complement(2143022..2143675) /gene="yodR" /locus_tag="BSU_19720" /old_locus_tag="BSU19720" /EC_number="2.8.3.-" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15150230, 21538109, 24914178; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative acyloate-acetoacetate CoA-transferase" /protein_id="NP_389853.1" /db_xref="EnsemblGenomes-Gn:BSU19720" /db_xref="EnsemblGenomes-Tr:CAB13863" /db_xref="GOA:O34466" /db_xref="InterPro:IPR004165" /db_xref="InterPro:IPR012791" /db_xref="SubtiList:BG13544" /db_xref="UniProtKB/Swiss-Prot:O34466" /translation="MGLGVAEREQIAKRAATEIKQGMIVNLGIGIPSLVPNFLKPDMQ VMFQAENGVLGIGESPEKGEEDAHLCNAAGYPVRAVKGASYFDTTMSFAMIRKGKIDI TILGALQVSQSGDLANWLVPGKKVPGMGGAMELAQKAKKVVVVMSHTDQKGRPKLTER CTLPLTAAGCVDLIITEKAVLEVDSHHFILKELMNGSTIDEVTRLTEAEIKIDMPFS* " gene complement(2143022..2143675) /gene="yodR" /locus_tag="BSU_19720" /old_locus_tag="BSU19720" CDS complement(2143660..2144349) /gene="yodS" /locus_tag="BSU_19730" /old_locus_tag="BSU19730" /EC_number="2.8.3.-" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15150230, 21538109, 24914178; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative oxoacid CoA-transferase" /protein_id="NP_389854.1" /db_xref="EnsemblGenomes-Gn:BSU19730" /db_xref="EnsemblGenomes-Tr:CAB13864" /db_xref="GOA:O34317" /db_xref="InterPro:IPR004163" /db_xref="InterPro:IPR004165" /db_xref="InterPro:IPR012792" /db_xref="SubtiList:BG13545" /db_xref="UniProtKB/Swiss-Prot:O34317" /translation="MAPFQKAISIDTAIADVRDGSVLMFGGFGGVGSPPSLIEAILDS GVTDLTVICNDAGFPDIGIGPLIVNQRVKTLIASHIGSNPVAGKQMTEGTLEVQFSPQ GTLAERIRAGGAGLGGILTDVGIDNQMVCEKKDIVTVAGKRYLIEEALTADFAFINAY IADEFGNLTYDKTARNMNPLMAMAARRTFAEAERIVPMGEISEEMIVTPGVFVEGVVR SEGVKWKWAWE*" gene complement(2143660..2144349) /gene="yodS" /locus_tag="BSU_19730" /old_locus_tag="BSU19730" CDS complement(2144356..2145690) /gene="yodT" /locus_tag="BSU_19740" /old_locus_tag="BSU19740" /EC_number="2.6.1.48" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 10839984, 15150230; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative aminovalerate aminotransferase" /protein_id="NP_389855.1" /db_xref="EnsemblGenomes-Gn:BSU19740" /db_xref="EnsemblGenomes-Tr:CAB13865" /db_xref="GOA:O34662" /db_xref="InterPro:IPR005814" /db_xref="InterPro:IPR015422" /db_xref="InterPro:IPR015424" /db_xref="SubtiList:BG13546" /db_xref="UniProtKB/Swiss-Prot:O34662" /translation="MSSYLIKPELSSAYPVVSYAKGSYVYDQTGKKYLDGSSGAVTCN IGHGVRDVTEKLKEQLDQVSFAYRSQFTSEPAEQLAALLAQELPGDVNWSFFVNSGSE AIETAMKIAIQYWQEKKQTQKSIFLSRWSSYHGITLGALSLSGFYERRYRFTHLIERY PAISAPHIYRLNHETEEDFVQTAADELDTMIKRIGSQFIAGFVAEPIIGAAGAAITPP PGYYERLSEVCRTHDVLFIADEVMTGLGRTGRMLATEHWDTVPDIAVLGKGLGAGYAP IAAAVVSDSIIETIKQGSGVIMSGHTYSAHPYSAKAALEVLRYVLKHGLIKQSEKKGA VLKKKLDEAASQSGIIGEVRGKGLLLGIEFVADQKTKKVFPPEQAITQLIVSEAKKRG LIVYPSKAGIDSGEGDAVIIAPPFTISDGEMEELISIFSETVAAVEKNLKKD*" gene complement(2144356..2145690) /gene="yodT" /locus_tag="BSU_19740" /old_locus_tag="BSU19740" CDS complement(2145671..2145826) /locus_tag="BSU_19745" /old_locus_tag="BSU19745" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="YP_009513966.1" /translation="MLDAEISKEPSLLGRLFLCEKVFAGNVMPPFGHSYNMVKGVLRW EHEQLFD*" gene complement(2145671..2145826) /locus_tag="BSU_19745" /old_locus_tag="BSU19745" promotor_-10 complement(2145709..2145727) /Source="Nicolas_upshift_promotors" /id="U1618" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1149 /SigmaFactorBS="aaggctctttttatgtgaaaaagtttttgcggggaacGTCAT GccgccatttggacacTCATACAATATGGTAAAAGgggttttgaggtgggagcatgag c" /listShort="yodT, yodS, yodR, yodQ, yodP, kamA, yokU, yozE" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2145725) /Source="Nicolas_upshifts" /id="U1618" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1149 /SigmaFactorBS="aaggctctttttatgtgaaaaagtttttgcggggaacGTCAT GccgccatttggacacTCATACAATATGGTAAAAGgggttttgaggtgggagcatgag c" /listShort="yodT, yodS, yodR, yodQ, yodP, kamA, yokU, yozE" /GFF_Attribute="listLong" promotor_-35 complement(2145743..2145748) /Source="Nicolas_upshift_promotors" /id="U1618" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1149 /SigmaFactorBS="aaggctctttttatgtgaaaaagtttttgcggggaacGTCAT GccgccatttggacacTCATACAATATGGTAAAAGgggttttgaggtgggagcatgag c" /listShort="yodT, yodS, yodR, yodQ, yodP, kamA, yokU, yozE" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2145820..2146053) /gene="yoyG" /locus_tag="BSU_19749" /old_locus_tag="BSU19749" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 20156992, 21670523; Product type f: factor" /codon_start=1 /transl_table=11 /product="putative toxin of a type I toxin family (sporulation operon)" /protein_id="YP_003097746.2" /db_xref="EnsemblGenomes-Gn:BSU19749" /db_xref="EnsemblGenomes-Tr:CAX52643" /db_xref="GOA:C0H435" /db_xref="InterPro:IPR010070" /db_xref="UniProtKB/Swiss-Prot:C0H435" /translation="MSGCILYFIISLHEIGVCTNHLGLGPHKMSYIVIRKDENSMYGY SGYGYGFGCGTNTFVLIVVLFILLIIVGAAFIC*" gene complement(2145820..2146053) /gene="yoyG" /locus_tag="BSU_19749" /old_locus_tag="BSU19749" downshifts complement(2145827) /Source="Nicolas_upshifts" /id="D1086" /incds=0 /nref=96 /ntot=237 /MaxReadThrough="2.70127" /MaxDrop="7.98506" /score="25.3834194" /energy="-16.5" /TU="NA" /idTUdmin="U1620" /TUdmin="-14" /isTUend="TRUE" promotor_-35 2145929..2145933 /Source="Nicolas_upshift_promotors" /id="U1619" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.999000999001" /psig=0 /xcortree=703 /SigmaFactorBS="agccaaatccgtaaccgtacccagagtatccaTACATgctgt tttCATCCTTTCTTATCAcgatatacgacattttatgcgggccaagtcccaaatggtt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2145942..2145956 /Source="Nicolas_upshift_promotors" /id="U1619" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.999000999001" /psig=0 /xcortree=703 /SigmaFactorBS="agccaaatccgtaaccgtacccagagtatccaTACATgctgt tttCATCCTTTCTTATCAcgatatacgacattttatgcgggccaagtcccaaatggtt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2145957 /Source="Nicolas_upshifts" /id="U1619" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.999000999001" /psig=0 /xcortree=703 /SigmaFactorBS="agccaaatccgtaaccgtacccagagtatccaTACATgctgt tttCATCCTTTCTTATCAcgatatacgacattttatgcgggccaagtcccaaatggtt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 complement(2145958..2145977) /Source="Nicolas_upshift_promotors" /id="U1620" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1350 /SigmaFactorBS="tatttccttacatgaaataggcgtttGCACAAACCAtttggg acttggccCGCATAAAATGTCGTATATCgtgataagaaaggatgaaaacagcatgtat g" /listShort="yoyG" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2145967) /Source="Nicolas_upshifts" /id="U1620" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1350 /SigmaFactorBS="tatttccttacatgaaataggcgtttGCACAAACCAtttggg acttggccCGCATAAAATGTCGTATATCgtgataagaaaggatgaaaacagcatgtat g" /listShort="yoyG" /GFF_Attribute="listLong" promotor_-35 complement(2145992..2146001) /Source="Nicolas_upshift_promotors" /id="U1620" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1350 /SigmaFactorBS="tatttccttacatgaaataggcgtttGCACAAACCAtttggg acttggccCGCATAAAATGTCGTATATCgtgataagaaaggatgaaaacagcatgtat g" /listShort="yoyG" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2146013..2146792) /gene="cgeE" /locus_tag="BSU_19750" /old_locus_tag="BSU19750" /function="16.5: Explore" /function="16.8: Protect" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:1729246, 7592393, 10066829, 27260256" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1729246, 7592393, 10066829, 27260256; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="protein involved in maturation of the outermost layer of the spore" /protein_id="NP_389856.1" /db_xref="EnsemblGenomes-Gn:BSU19750" /db_xref="EnsemblGenomes-Tr:CAB13866" /db_xref="GOA:P42093" /db_xref="InterPro:IPR000182" /db_xref="InterPro:IPR016181" /db_xref="SubtiList:BG11197" /db_xref="UniProtKB/Swiss-Prot:P42093" /translation="MTGHYSKTEHQYILLTSESASFDHYSVYRDPQLPQIFSHNFVQL HDTFPLERLLNFLPSVPKLLDANYLHLKASPQHVFPLGLKQSLVKSGFVVEDELLYDM KLSDWKGQMGHPLTAWGTAKSLSDGSSIMKIYDSIYIGEAIAEQKLKRKYPFYEADII ILVVCYSDQAQKVPIGCGELFIDHQEKTAKIEEVAILDQFQRKGYGSILVKEMLSIAK SLGMEAAYLVAASTDGATQFYEKLTFKKYERVHTVFHYFLT*" gene complement(2146013..2146792) /gene="cgeE" /locus_tag="BSU_19750" /old_locus_tag="BSU19750" CDS complement(2146821..2148101) /gene="cgeD" /locus_tag="BSU_19760" /old_locus_tag="BSU19760" /function="16.13: Shape" /function="16.5: Explore" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:1729246, 10066829, 21665972" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1729246, 10066829, 21665972; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="putative glycosyltransferase involved in maturation of the outermost layer of the spore" /protein_id="NP_389857.1" /db_xref="EnsemblGenomes-Gn:BSU19760" /db_xref="EnsemblGenomes-Tr:CAB13867" /db_xref="InterPro:IPR001173" /db_xref="InterPro:IPR029044" /db_xref="SubtiList:BG11196" /db_xref="UniProtKB/Swiss-Prot:P42092" /translation="MGEKVSIILTSYNKPDYLQKAIESVIQQTHDLWELFIMDDHSNA ETTAVIHKYLHDRRIQYHNSFVHPADRLKTARYATLINSALPFADGDYISYLTDDTVY HPERLSRMVQEFSHKPEAQAVYSKQKVVHVNERGEEISHFYRNANAVLDQAAFQVDHC SVMHRRSLLNLIHHKFGGYWDDDMKHWNHGDAIFWARLNNFTPFLPINEVLDTTYKTP DSFQNAYRFLPADLIDGSFVKGSDQNVYFFDQGVRHPVGEKWGFLYLNRTVAVPDPYL FQYRIGKILNIPNYILVKEADHPAIFYIEAGKKRRIVDQYAFQFYQFQRKDIVTIGKE EMETLPEGPPITWKRSELIKNPPGRRLFFIEREPFLFLNGVFHPISEQVTRKFFLHQK PISASFRNIQQFPIGKPFYPVYDEIIKKLNIATE*" gene complement(2146821..2148101) /gene="cgeD" /locus_tag="BSU_19760" /old_locus_tag="BSU19760" promotor_-10 complement(2147469..2147487) /Source="Nicolas_upshift_promotors" /id="U1621" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2789 /SigmaFactorBS="attggaatcatggcgacgcaattttttgggcgagactCAACA ACTttaccccatttctGCCGATAAATGAAGTATTAgacacaacctataaaaccccaga t" /listShort="cgeE, yoyG" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2147485) /Source="Nicolas_upshifts" /id="U1621" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2789 /SigmaFactorBS="attggaatcatggcgacgcaattttttgggcgagactCAACA ACTttaccccatttctGCCGATAAATGAAGTATTAgacacaacctataaaaccccaga t" /listShort="cgeE, yoyG" /GFF_Attribute="listLong" promotor_-35 complement(2147501..2147508) /Source="Nicolas_upshift_promotors" /id="U1621" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2789 /SigmaFactorBS="attggaatcatggcgacgcaattttttgggcgagactCAACA ACTttaccccatttctGCCGATAAATGAAGTATTAgacacaacctataaaaccccaga t" /listShort="cgeE, yoyG" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(2148069..2148087) /Source="Nicolas_upshift_promotors" /id="U1622" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.986013986013986" /psig="0.986013986013986" /xcortree=955 /SigmaFactorBS="ggagccgtttttatgtttgacggcgggaggcGGTATAgatgg gagagaaagtGTCTATTATTTTAACAAGTtacaacaaacccgattatttgcaaaaagc g" /listShort="cgeD, cgeE, yoyG" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2148079) /Source="Nicolas_upshifts" /id="U1622" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.986013986013986" /psig="0.986013986013986" /xcortree=955 /SigmaFactorBS="ggagccgtttttatgtttgacggcgggaggcGGTATAgatgg gagagaaagtGTCTATTATTTTAACAAGTtacaacaaacccgattatttgcaaaaagc g" /listShort="cgeD, cgeE, yoyG" /GFF_Attribute="listLong" promotor_-35 complement(2148103..2148108) /Source="Nicolas_upshift_promotors" /id="U1622" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.986013986013986" /psig="0.986013986013986" /xcortree=955 /SigmaFactorBS="ggagccgtttttatgtttgacggcgggaggcGGTATAgatgg gagagaaagtGTCTATTATTTTAACAAGTtacaacaaacccgattatttgcaaaaagc g" /listShort="cgeD, cgeE, yoyG" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2148166..2148471) /gene="cgeC" /locus_tag="BSU_19770" /old_locus_tag="BSU19770" /function="16.5: Explore" /function="16.8: Protect" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:1729246, 10066829, 21665972" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1729246, 10066829, 21665972; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="protein involved in maturation of the outermost layer of the spore" /protein_id="NP_389858.1" /db_xref="EnsemblGenomes-Gn:BSU19770" /db_xref="EnsemblGenomes-Tr:CAB13868" /db_xref="SubtiList:BG11195" /db_xref="UniProtKB/Swiss-Prot:P42091" /translation="MDLEKQVDREENQDDLHFILLLLILLIRQSSSEGNPSDLRRQLV FAKELGVPVSKVNLINGDTLQNVIVKEVLTDLVIFQNPLNNTRSHVSLSSVVSWGAF* " gene complement(2148166..2148471) /gene="cgeC" /locus_tag="BSU_19770" /old_locus_tag="BSU19770" downshifts complement(2148299) /Source="Nicolas_upshifts" /id="D1087" /incds=1 /nref=2 /ntot=28 /MaxReadThrough="5.32389" /MaxDrop="2.61092" /score="23.1569137" /energy="-13.4" /TU="U1623" /idTUdmin="U1623" /TUdmin="-2310" /isTUend="FALSE" promotor_-10 complement(2148495..2148514) /Source="Nicolas_upshift_promotors" /id="U1623" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1417 /SigmaFactorBS="ggaaaatgctgattttttaatggagtggacataGCCTATACC AtaaatcgaagtcgCACATATTGTGAAACAGAGAtaaggataagggagagggatgatt t" /listShort="cgeC, cgeD, cgeE" /listLong="yoyG" /label="promotor_-10" upshifts complement(2148510) /Source="Nicolas_upshifts" /id="U1623" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1417 /SigmaFactorBS="ggaaaatgctgattttttaatggagtggacataGCCTATACC AtaaatcgaagtcgCACATATTGTGAAACAGAGAtaaggataagggagagggatgatt t" /listShort="cgeC, cgeD, cgeE" /listLong="yoyG" promotor_-35 complement(2148528..2148537) /Source="Nicolas_upshift_promotors" /id="U1623" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1417 /SigmaFactorBS="ggaaaatgctgattttttaatggagtggacataGCCTATACC AtaaatcgaagtcgCACATATTGTGAAACAGAGAtaaggataagggagagggatgatt t" /listShort="cgeC, cgeD, cgeE" /listLong="yoyG" /label="promotor_-35" promotor_-35 2148607..2148616 /Source="Nicolas_upshift_promotors" /id="U1624" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1410 /SigmaFactorBS="cttaaatagatgaaaaatagatcaggtacggcgttcgACTCA TACCAaataacagccggaAGAATATGAATAACGTGAGTtcactatcgaataggaggtg t" /listShort="cgeA, cgeB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2148630..2148649 /Source="Nicolas_upshift_promotors" /id="U1624" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1410 /SigmaFactorBS="cttaaatagatgaaaaatagatcaggtacggcgttcgACTCA TACCAaataacagccggaAGAATATGAATAACGTGAGTtcactatcgaataggaggtg t" /listShort="cgeA, cgeB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2148630 /Source="Nicolas_upshifts" /id="U1624" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1410 /SigmaFactorBS="cttaaatagatgaaaaatagatcaggtacggcgttcgACTCA TACCAaataacagccggaAGAATATGAATAACGTGAGTtcactatcgaataggaggtg t" /listShort="cgeA, cgeB" /GFF_Attribute="listLong" upshifts complement(2148651) /Source="Nicolas_upshifts" /id="U1625" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.999000999001" /psig="0.000999000999001" /xcortree=1242 /SigmaFactorBS="taaatccttttttaactgtgcattttcagagCTCATtacaca caCCTCCTATTCGATAGtgaactcacgttattcatattcttccggctgttatttggta t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 complement(2148653..2148667) /Source="Nicolas_upshift_promotors" /id="U1625" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.999000999001" /psig="0.000999000999001" /xcortree=1242 /SigmaFactorBS="taaatccttttttaactgtgcattttcagagCTCATtacaca caCCTCCTATTCGATAGtgaactcacgttattcatattcttccggctgttatttggta t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 complement(2148676..2148680) /Source="Nicolas_upshift_promotors" /id="U1625" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.999000999001" /psig="0.000999000999001" /xcortree=1242 /SigmaFactorBS="taaatccttttttaactgtgcattttcagagCTCATtacaca caCCTCCTATTCGATAGtgaactcacgttattcatattcttccggctgttatttggta t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" CDS 2148676..2149077 /gene="cgeA" /locus_tag="BSU_19780" /old_locus_tag="BSU19780" /function="16.5: Explore" /function="16.13: Shape" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:759239, 14702409, 15621419, 19933362, 21665972" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 759239, 14702409, 15621419, 19933362, 21665972; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="spore outermost layer component" /protein_id="NP_389859.1" /db_xref="EnsemblGenomes-Gn:BSU19780" /db_xref="EnsemblGenomes-Tr:CAB13869" /db_xref="SubtiList:BG11193" /db_xref="UniProtKB/Swiss-Prot:P42089" /translation="MSSENAQLKKDLIKAVLSPLFPTATEGGENMDSNLKALLDAAID QKVDESETVTAESILDPSLPARWIFARITPGTTISIVTDSGDMIGPVVFVAFDQVHGI VFVTQESSVTPAGQATTLIDVDKVESVTFFS*" gene 2148676..2149077 /gene="cgeA" /locus_tag="BSU_19780" /old_locus_tag="BSU19780" CDS 2149084..2150037 /gene="cgeB" /locus_tag="BSU_19790" /old_locus_tag="BSU19790" /function="16.8: Protect" /function="16.13: Shape" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:1729246, 10066829, 21665972" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1729246, 10066829, 21665972; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="protein involved in maturation of the outermost layer of the spore" /protein_id="NP_389860.2" /db_xref="EnsemblGenomes-Gn:BSU19790" /db_xref="EnsemblGenomes-Tr:CAB13870" /db_xref="InterPro:IPR024542" /db_xref="SubtiList:BG11194" /db_xref="UniProtKB/Swiss-Prot:P42090" /translation="MKVLYIQSGYGGIYSYFDRWAEECFQNTHTEYMIADKPEAESLM KIEAFQPDFTLMMVGDRVPHDWLTWLKGKDIPVYVWLTEDPFYMDISLQVIKLADAIL TIEQNAALYYQELGYQNVYYVPIPVNHRLFKKMGTEHSYHSNLLIIGYPYPNRVQLMK EAVHLPFTVRVIGKEWGKYLPKKVLKQPHIDVVSTWVPPEQAVHYYNGADIVINAHRP YHFAFNQNTMRIKNASFNNRTFDIAACEAFQLTDLPAAHPFSSIISYHGMNDFKEKAA FYINHPEERQKAAAANYKETVPAFTFDELPAKLKAIHLALS*" gene 2149084..2150037 /gene="cgeB" /locus_tag="BSU_19790" /old_locus_tag="BSU19790" downshifts 2150027 /Source="Nicolas_upshifts" /id="D1088" /incds=0 /nref=4 /ntot=33 /MaxReadThrough="2.94229" /MaxDrop="5.87549" /score="22.1420541" /energy="-9" /TU="NA" /idTUdmin="U1624" /TUdmin=0 /isTUend="TRUE" CDS complement(2150108..2151256) /gene="phyC" /locus_tag="BSU_19800" /old_locus_tag="BSU19800" /EC_number="3.1.3.8" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:10679209, 12101298, 12111145, 12556126, 16980498, 17269748, 21463636" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10679209, 12101298, 12111145, 12556126, 16980498, 17269748, 21463636; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="phytase" /protein_id="NP_389861.1" /db_xref="EnsemblGenomes-Gn:BSU19800" /db_xref="EnsemblGenomes-Tr:CAB13871" /db_xref="GOA:P42094" /db_xref="InterPro:IPR003431" /db_xref="InterPro:IPR011042" /db_xref="SubtiList:BG11198" /db_xref="UniProtKB/Swiss-Prot:P42094" /translation="MKVPKTMLLSTAAGLLLSLTATSVSAHYVNEEHHFKVTAHTETD PVASGDDAADDPAIWVHEKHPEKSKLITTNKKSGLVVYDLDGKQLHSYEFGKLNNVDL RYDFPLNGEKIDIAAASNRSEGKNTIEVYAIDGDKGKLKSITDPNHPISTNISEVYGF SLYHSQKTGAFYALVTGKQGEFEQYEIVDGGKGYVTGKKVREFKLNSQTEGLVADDEY GNLYIAEEDEAIWKFNAEPGGGSKGQVVDRATGDHLTADIEGLTIYYAPNGKGYLMAS SQGNNSYAMYERQGKNRYVANFEITDGEKIDGTSDTDGIDVLGFGLGPKYPYGIFVAQ DGENIDNGQAVNQNFKIVSWEQIAQHLGEMPDLHKQVNPRKLKDRSDG*" gene complement(2150108..2151256) /gene="phyC" /locus_tag="BSU_19800" /old_locus_tag="BSU19800" downshifts complement(2150125) /Source="Nicolas_upshifts" /id="D1089" /incds=0 /nref=16 /ntot=104 /MaxReadThrough="2.64059" /MaxDrop="5.59857" /score="17.7154517" /energy="-8.7" /TU="NA" /idTUdmin="U1629" /TUdmin=2024 /isTUend="FALSE" promotor_-35 2151269..2151273 /Source="Nicolas_upshift_promotors" /id="U1627" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.642357642357642" /psig="0.988011988011988" /xcortree=1704 /SigmaFactorBS="tgtttttggaaccttcatttggtaccctccTCTTTtatcact aacactacTATTGTAAAATATATACAGGtgattaccgtgaggaaaatgaacctttttt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" misc_feature complement(2151282..2151301) /Source="Nicolas_upshift_promotors" /id="U1626" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.619380619380619" /psig="0.994005994005994" /xcortree=564 /SigmaFactorBS="cagaaaccctataaaaaaaggttcattttcctcacggtaatc acctgtatATATTTTACAATAGTAGTGTtagtgataaaagaggagggtaccaaatgaa g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" promotor_-10 2151289..2151308 /Source="Nicolas_upshift_promotors" /id="U1627" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.642357642357642" /psig="0.988011988011988" /xcortree=1704 /SigmaFactorBS="tgtttttggaaccttcatttggtaccctccTCTTTtatcact aacactacTATTGTAAAATATATACAGGtgattaccgtgaggaaaatgaacctttttt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2151291) /Source="Nicolas_upshifts" /id="U1626" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.619380619380619" /psig="0.994005994005994" /xcortree=564 /SigmaFactorBS="cagaaaccctataaaaaaaggttcattttcctcacggtaatc acctgtatATATTTTACAATAGTAGTGTtagtgataaaagaggagggtaccaaatgaa g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" upshifts 2151299 /Source="Nicolas_upshifts" /id="U1627" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.642357642357642" /psig="0.988011988011988" /xcortree=1704 /SigmaFactorBS="tgtttttggaaccttcatttggtaccctccTCTTTtatcact aacactacTATTGTAAAATATATACAGGtgattaccgtgaggaaaatgaacctttttt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 2151560..2151568 /Source="Nicolas_upshift_promotors" /id="U1628" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.867132867132867" /psig="0.867132867132867" /xcortree=1422 /SigmaFactorBS="atcattcccctaaattttgttttattggttgctttCATTAAT TCgattacaaagttgAACATATGATGCATGGTAGAgaaacgagagttggaggataagc c" /listShort="ypqP" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2151582..2151601 /Source="Nicolas_upshift_promotors" /id="U1628" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.867132867132867" /psig="0.867132867132867" /xcortree=1422 /SigmaFactorBS="atcattcccctaaattttgttttattggttgctttCATTAAT TCgattacaaagttgAACATATGATGCATGGTAGAgaaacgagagttggaggataagc c" /listShort="ypqP" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2151585 /Source="Nicolas_upshifts" /id="U1628" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.867132867132867" /psig="0.867132867132867" /xcortree=1422 /SigmaFactorBS="atcattcccctaaattttgttttattggttgctttCATTAAT TCgattacaaagttgAACATATGATGCATGGTAGAgaaacgagagttggaggataagc c" /listShort="ypqP" /GFF_Attribute="listLong" CDS 2151626..2152651 /NCBI_locus_tag="A8O17_RS10335" /NCBI_old_locus_tag="A8O17_10335" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_014664318.1" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /codon_start=1 /transl_table=11 /product="polysaccharide biosynthesis protein" /protein_id="WP_003230816.1" /locus_tag="Delta6_BSU_19810-BSU_21670" /modified_by="User" /translation="MPKQQTAELKPFFHNKTVLVTGGTGSIGSQIVKRLLMLTPKQVI VFSKDDSKQYVMSQKYAEDKRLLFVLGDVRDHRRVNQVMKGVDIVFHAAALKQVPTCE DHPFEAIQTNLIGGQNVVEAALSHRVQHVINISTDKAVSPVNTMGATKLLSEKLFHQA NRHVQNKGTLFCSVRFGNVLGSRGSVIPILFEQMMEGEPLTITDKNMTRFFMSIDDAA TLTLQSAAITKGGETFIFKMESLKLEELIHGFEEYASQHGLPRPAAVEVGKRPGEKLH EELTSPHEIESLYEWGNLYAILPEPEKHPDFRKVNLPGYQSDQAPLITKERIAQIIEE LHQEKKA*" /label="Delta6_BSU_19810-BSU_21670" gene 2151626..2152651 /NCBI_locus_tag="A8O17_RS10335" /NCBI_old_locus_tag="A8O17_10335" /locus_tag="Delta6_BSU_19810-BSU_21670" /modified_by="User" /label="Delta6_BSU_19810-BSU_21670" downshifts 2152029 /Source="Nicolas_upshifts" /id="D1090" /incds=0 /nref=18 /ntot=39 /MaxReadThrough="0.75679" /MaxDrop="7.79081" /score="-6.65536786" /energy="-8.7" /TU="NA" /idTUdmin="U1628" /TUdmin=0 /isTUend="TRUE" SCAR 2152045..2152046 /created_by="User" /note="deletion occured in betwen marked nucleotides" /modified_by="User" /label="Delta_SP_beta" downshifts 2152643 /Source="Nicolas_upshifts" /id="D1134" /incds=0 /nref=22 /ntot=177 /MaxReadThrough="2.90949" /MaxDrop="5.54327" /score="-2.31796312" /energy="-13.5" /TU="NA" /idTUdmin="U1701" /TUdmin=0 /isTUend="TRUE" CDS complement(2152695..2153126) /gene="msrB" /locus_tag="BSU_21680" /old_locus_tag="BSU21680" /EC_number="1.8.4.12" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 15680230, 16803968, 17031545, 18239417, 18662407; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="peptide methionine R-sulfoxide reductase" /protein_id="NP_390051.1" /db_xref="EnsemblGenomes-Gn:BSU21680" /db_xref="EnsemblGenomes-Tr:CAB14086" /db_xref="GOA:P54155" /db_xref="InterPro:IPR002579" /db_xref="InterPro:IPR011057" /db_xref="InterPro:IPR028427" /db_xref="PDB:2KZN" /db_xref="PDB:3E0O" /db_xref="SubtiList:BG11628" /db_xref="UniProtKB/Swiss-Prot:P54155" /translation="MAYNKEEKIKSLNRMQYEVTQNNGTEPPFQNEYWDHKEEGLYVD IVSGKPLFTSKDKFDSQCGWPSFTKPIEEEVEEKLDTSHGMIRTEVRSRTADSHLGHV FNDGPGPNGLRYCINSAALRFVPKHKLKEEGYESYLHLFNK*" gene complement(2152695..2153126) /gene="msrB" /locus_tag="BSU_21680" /old_locus_tag="BSU21680" downshifts complement(2152700) /Source="Nicolas_upshifts" /id="D1135" /incds=0 /nref=229 /ntot=262 /MaxReadThrough="2.46559" /MaxDrop="6.77483" /score="1.42817565" /energy="-12.3" /TU="NA" /idTUdmin="U1704" /TUdmin="-3" /isTUend="TRUE" CDS complement(2153127..2153660) /gene="msrA" /locus_tag="BSU_21690" /old_locus_tag="BSU21690" /EC_number="1.8.4.11" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:9573155, 16803968, 17062561, 18662407" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9573155, 16803968, 17062561, 18662407; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="peptide methionine S-sulfoxide reductase" /protein_id="NP_390052.1" /db_xref="EnsemblGenomes-Gn:BSU21690" /db_xref="EnsemblGenomes-Tr:CAB14087" /db_xref="GOA:P54154" /db_xref="InterPro:IPR002569" /db_xref="InterPro:IPR036509" /db_xref="SubtiList:BG11627" /db_xref="UniProtKB/Swiss-Prot:P54154" /translation="MSEKKEIATFAGGCFWCMVKPFDEQPGIEKVVSGYTGGHTENPT YEEVCSETTGHREAVQITFHPDVFPYEKLLELFWQQIDPTDAGGQFADRGSSYRAAIF YHNDKQKELAEASKQRLAESGIFKDPIVTDILKAEPFYEAEGYHQHFYKKNPAHYQRY RTGSGRAGFISEHWGAK*" gene complement(2153127..2153660) /gene="msrA" /locus_tag="BSU_21690" /old_locus_tag="BSU21690" promotor_-35 2153664..2153670 /Source="Nicolas_upshift_promotors" /id="U1703" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.648351648351648" /psig="0.946053946053946" /xcortree=3087 /SigmaFactorBS="agcctcctgcaaatgtggcgatttcttttttttcagacatac tGGTGCCTcctttgttaataCGTGGTATTATTATATTATAgcatgtaaaaatagaatg a" /listShort="S817, ypoP, S818" /GFF_Attribute="listLong" /label="promotor_-35" S_feature 2153681..2153791 /Source="Nicolas_S_feature" /locus_tag="new_2288083_2288193" /HighExp="B60, Lbstat, Cold, M9-stat, T4.0H, LoTm, S0, T3.30H, BC, Sw" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.946" /TUlongSig="NA" /TUlongPSig="NA" /label="S817" upshifts 2153681 /Source="Nicolas_upshifts" /id="U1703" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.648351648351648" /psig="0.946053946053946" /xcortree=3087 /SigmaFactorBS="agcctcctgcaaatgtggcgatttcttttttttcagacatac tGGTGCCTcctttgttaataCGTGGTATTATTATATTATAgcatgtaaaaatagaatg a" /listShort="S817, ypoP, S818" /GFF_Attribute="listLong" promotor_-10 2153683..2153702 /Source="Nicolas_upshift_promotors" /id="U1703" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.648351648351648" /psig="0.946053946053946" /xcortree=3087 /SigmaFactorBS="agcctcctgcaaatgtggcgatttcttttttttcagacatac tGGTGCCTcctttgttaataCGTGGTATTATTATATTATAgcatgtaaaaatagaatg a" /listShort="S817, ypoP, S818" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-10 complement(2153688..2153707) /Source="Nicolas_upshift_promotors" /id="U1704" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.762237762237762" /psig=1 /xcortree=2072 /SigmaFactorBS="gcatattgcttaaaacctatagattttattgaaaagcagaat caTTttcattctatttttaCATGCTATAATATAATAATAccacgtattaacaaaggag g" /listShort="msrA, msrB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2153708) /Source="Nicolas_upshifts" /id="U1704" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.762237762237762" /psig=1 /xcortree=2072 /SigmaFactorBS="gcatattgcttaaaacctatagattttattgaaaagcagaat caTTttcattctatttttaCATGCTATAATATAATAATAccacgtattaacaaaggag g" /listShort="msrA, msrB" /GFF_Attribute="listLong" promotor_-35 complement(2153723..2153724) /Source="Nicolas_upshift_promotors" /id="U1704" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.762237762237762" /psig=1 /xcortree=2072 /SigmaFactorBS="gcatattgcttaaaacctatagattttattgaaaagcagaat caTTttcattctatttttaCATGCTATAATATAATAATAccacgtattaacaaaggag g" /listShort="msrA, msrB" /GFF_Attribute="listLong" /label="promotor_-35" CDS 2153792..2154217 /gene="ypoP" /locus_tag="BSU_21700" /old_locus_tag="BSU21700" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 9571784, 10809700; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative transcriptional regulator (MarR family)" /protein_id="NP_390053.1" /db_xref="EnsemblGenomes-Gn:BSU21700" /db_xref="EnsemblGenomes-Tr:CAB14088" /db_xref="GOA:P54182" /db_xref="InterPro:IPR000835" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG11626" /db_xref="UniProtKB/Swiss-Prot:P54182" /translation="MKVRTQMMYDMETLLRKVFKQIRNEINEILDKELSRNEFTILRI LSEQGPKKVTEFAPILEVSASHITAVTDALVEKEWITRIRSKEDRRIIRIHITEAGEK VLQHFNEKKTEYFFKRFDCYTDAELATLIELFSKLDKKR*" gene 2153792..2154217 /gene="ypoP" /locus_tag="BSU_21700" /old_locus_tag="BSU21700" downshifts 2154205 /Source="Nicolas_upshifts" /id="D1136" /incds=0 /nref=92 /ntot=248 /MaxReadThrough="4.04021" /MaxDrop="5.35086" /score="-1.90494373" /energy="-7" /TU="U1703" /idTUdmin="U1703" /TUdmin="-1254" /isTUend="FALSE" S_feature 2154250..2155481 /Source="Nicolas_S_feature" /locus_tag="new_2288652_2289883" /HighExp="Cold, ferm, nit, C30, S0, Lbstat, T3.30H, T-4.40H, T5.0H, G135" /AntisenseName="dinF" /AntisenseCor="0.270994122332881" /AntisenseRegPval="-5.2" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.946" /TUlongSig="NA" /TUlongPSig="NA" /label="S818" CDS complement(2154267..2155604) /gene="dinF" /locus_tag="BSU_21710" /old_locus_tag="BSU21710" /function="16.1: Circulate" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1c: Function from experimental evidences in the studied genus; PubMedId: 11583854, 15849754, 16850406, 22933559, 26246409; Product type t : transporter" /codon_start=1 /transl_table=11 /product="damage inducible, Na+ driven multidrug efflux pump" /protein_id="NP_390054.1" /db_xref="EnsemblGenomes-Gn:BSU21710" /db_xref="EnsemblGenomes-Tr:CAB14089" /db_xref="GOA:P54181" /db_xref="InterPro:IPR002528" /db_xref="SubtiList:BG11625" /db_xref="UniProtKB/Swiss-Prot:P54181" /translation="MKAYDFTQGNVLKQLVLFSMPIMLGNALQVSFQFIDSLWIGNLL GAKALGAAAVSSTIVLTVLSFILGLNNATLTILSQQKGKDDIKGMASYINAFVVLLTG LSIGFGAAGFFLSELLLRLLKTPESMIPLAETYLQIQFIGILFLFGYNFISTVLRALG DSKTPLRFIAFAVVLNTVLAPLFISVFRMGIAGAAYSTILSQGIAFLYGLFYVIKHKL VPFSIPRMPKWEESALILKLGIPAGLQMMVITGGMMAIMSVVNSYGDHVVSGFGAVQR LDSIITLPAMAAGTAVNSMAGQNIGIGNEKRVGTIARLGVIAVISCMLVIAVMIWVFG KYLIRLFISEPDAVAFGEQYLKWIAFFYPFIGVNFVLNGIVRAAGAMLQVLVLNLISF WVLRYPFTALFSAWLGQKGIGLGIGMSFLFSSCAAFLYYRYGRWKAMKLFTEK*" gene complement(2154267..2155604) /gene="dinF" /locus_tag="BSU_21710" /old_locus_tag="BSU21710" CDS complement(2155676..2155870) /gene="ypmT" /locus_tag="BSU_21720" /old_locus_tag="BSU21720" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_390055.1" /db_xref="EnsemblGenomes-Gn:BSU21720" /db_xref="EnsemblGenomes-Tr:CAB14090" /db_xref="GOA:P54180" /db_xref="InterPro:IPR035403" /db_xref="SubtiList:BG11624" /db_xref="UniProtKB/Swiss-Prot:P54180" /translation="MKRIYQYFSLLSFTFSLYFGWLAYHHLAAEDMDQMYLNVSYCAL FLSVMVFTFGMRDRKKTDKS*" gene complement(2155676..2155870) /gene="ypmT" /locus_tag="BSU_21720" /old_locus_tag="BSU21720" downshifts complement(2155689) /Source="Nicolas_upshifts" /id="D1137" /incds=0 /nref=123 /ntot=248 /MaxReadThrough="3.84998" /MaxDrop="4.80224" /score="-2.26655222" /energy="-15.5" /TU="U1705" /idTUdmin="U1707" /TUdmin=0 /isTUend="TRUE" CDS complement(2155883..2156446) /gene="ypmS" /locus_tag="BSU_21730" /old_locus_tag="BSU21730" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_390056.1" /db_xref="EnsemblGenomes-Gn:BSU21730" /db_xref="EnsemblGenomes-Tr:CAB14091" /db_xref="GOA:P54179" /db_xref="InterPro:IPR018672" /db_xref="SubtiList:BG11623" /db_xref="UniProtKB/Swiss-Prot:P54179" /translation="MNKWKRLFFILLAINFILAAGFVALVLLPGEQAQVKDASESEYG FQVTSTKESLAAFVNSYLNDKASNKLDYKVEIDDDVHVAGKIKAFSTSIDAFIAFEPT VKKNGDVELNVTKFSLGKLSIPISFVLNYMDSFYELPSFVHVHPGDKSIEVRLSEMPL TNGMYVKADKINLEKDEIEFSYYHPKQ*" gene complement(2155883..2156446) /gene="ypmS" /locus_tag="BSU_21730" /old_locus_tag="BSU21730" CDS complement(2156456..2157223) /gene="ypmR" /locus_tag="BSU_21740" /old_locus_tag="BSU21740" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 17220230; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative exported lipase/acylhydrolase (lipoprotein)" /protein_id="NP_390057.1" /db_xref="EnsemblGenomes-Gn:BSU21740" /db_xref="EnsemblGenomes-Tr:CAB14092" /db_xref="GOA:P40766" /db_xref="InterPro:IPR013830" /db_xref="InterPro:IPR036514" /db_xref="SubtiList:BG11022" /db_xref="UniProtKB/Swiss-Prot:P40766" /translation="MKLRIFSIMASLILLLTACTSIRTSSEGKQKAHETKTKEHIVIA AVGDSLTEGVGDPDGKGYVGKVADSIRSDKQVKTVDVKNYAVKGNRSDDLLEKLKDKK VQKGIKDADYVFFTIGGNDLMKILRQNFLQLTVEPFQEAEKPYEKRFEKIISEIRELN DHAELIYVSMYNPFTFTLSELNEINGVVTDWNHIAEKELKKDKHAKIVHIEDLFNQKS DSSRISEEDDFHPNGTGYSLIAKRVYQAIKKEGLPKE*" gene complement(2156456..2157223) /gene="ypmR" /locus_tag="BSU_21740" /old_locus_tag="BSU21740" promotor_-10 complement(2157247..2157266) /Source="Nicolas_upshift_promotors" /id="U1705" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.735264735264735" /psig=1 /xcortree=2250 /SigmaFactorBS="aagtcagccagtacactcaagtaagctaagagactaggcaTT TGCAAAtcttctaaaaCATGATACACTTTCCACTAGtagaatgggaaggagcaacaag a" /listShort="ypmR, ypmS, ypmT, dinF" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2157264) /Source="Nicolas_upshifts" /id="U1705" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.735264735264735" /psig=1 /xcortree=2250 /SigmaFactorBS="aagtcagccagtacactcaagtaagctaagagactaggcaTT TGCAAAtcttctaaaaCATGATACACTTTCCACTAGtagaatgggaaggagcaacaag a" /listShort="ypmR, ypmS, ypmT, dinF" /GFF_Attribute="listLong" promotor_-35 complement(2157277..2157284) /Source="Nicolas_upshift_promotors" /id="U1705" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.735264735264735" /psig=1 /xcortree=2250 /SigmaFactorBS="aagtcagccagtacactcaagtaagctaagagactaggcaTT TGCAAAtcttctaaaaCATGATACACTTTCCACTAGtagaatgggaaggagcaacaag a" /listShort="ypmR, ypmS, ypmT, dinF" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2157301..2157882) /gene="scuA" /locus_tag="BSU_21750" /old_locus_tag="BSU21750" /function="16.10: Respire" /experiment="publication(s) with functional evidences, PMID:10837475, 14680962, 14766920, 16305244, 19027886, 29131589" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10837475, 14680962, 14766920, 16305244, 19027886, 29131589; Product type f : factor" /codon_start=1 /transl_table=11 /product="assembly factor BSco of the Cu(A) site of cytochrome c oxidase" /protein_id="NP_390058.2" /db_xref="EnsemblGenomes-Gn:BSU21750" /db_xref="EnsemblGenomes-Tr:CAB14093" /db_xref="GOA:P54178" /db_xref="InterPro:IPR003782" /db_xref="InterPro:IPR013766" /db_xref="InterPro:IPR036249" /db_xref="PDB:1ON4" /db_xref="PDB:1XZO" /db_xref="SubtiList:BG11622" /db_xref="UniProtKB/Swiss-Prot:P54178" /translation="MKVIKGLTAGLIFLFLCACGGQQIKDPLNYEVEPFTFQNQDGKN VSLESLKGEVWLADFIFTNCETICPPMTAHMTDLQKKLKAENIDVRIISFSVDPENDK PKQLKKFAANYPLSFDNWDFLTGYSQSEIEEFALKSFKAIVKKPEGEDQVIHQSSFYL VGPDGKVLKDYNGVENTPYDDIISDVKSASTLK*" gene complement(2157301..2157882) /gene="scuA" /locus_tag="BSU_21750" /old_locus_tag="BSU21750" S_feature complement(2157883..2157998) /Source="Nicolas_S_feature" /locus_tag="new_2292285_2292400_c" /HighExp="T5.0H, T3.30H, S2, T3.0H, BC, T2.30H, T4.0H, S1, HiOs, S3" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S819" CDS complement(2158030..2158281) /gene="ypmP" /locus_tag="BSU_21760" /old_locus_tag="BSU21760" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 15060025, 22720735" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_390059.1" /db_xref="EnsemblGenomes-Gn:BSU21760" /db_xref="EnsemblGenomes-Tr:CAB14094" /db_xref="InterPro:IPR019687" /db_xref="SubtiList:BG11621" /db_xref="UniProtKB/Swiss-Prot:P54177" /translation="MLLKSLEFKRGDGIQVKVTEIPVLKEDEHYFFMLHHHLQFYLKE VFSSNSRAKVYSFRHYMKRRMKWADYQAVFHQEVLKHNA*" gene complement(2158030..2158281) /gene="ypmP" /locus_tag="BSU_21760" /old_locus_tag="BSU21760" downshifts complement(2158043) /Source="Nicolas_upshifts" /id="D1138" /incds=0 /nref=2 /ntot=117 /MaxReadThrough="4.5803" /MaxDrop="2.91481" /score="26.0320926" /energy="-21.8" /TU="U1707" /idTUdmin="U1706" /TUdmin=0 /isTUend="TRUE" misc_feature complement(2158304..2158323) /Source="Nicolas_upshift_promotors" /id="U1706" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.896103896103896" /psig=1 /xcortree=626 /SigmaFactorBS="ttgctaatctaatttttttacacaaccgcgcaaaatgacaga cagcccggctggcATCATATATAATAGAAGAAAaacaaaaaagaggattgatagcttg t" /listShort="ypmP" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(2158318) /Source="Nicolas_upshifts" /id="U1706" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.896103896103896" /psig=1 /xcortree=626 /SigmaFactorBS="ttgctaatctaatttttttacacaaccgcgcaaaatgacaga cagcccggctggcATCATATATAATAGAAGAAAaacaaaaaagaggattgatagcttg t" /listShort="ypmP" /GFF_Attribute="listLong" CDS complement(2158367..2159635) /gene="ilvA" /locus_tag="BSU_21770" /old_locus_tag="BSU21770" /EC_number="4.3.1.19" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:12618455, 13878122, 1459955, 15060025, 18855421, 22094463, 27260660" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12618455, 13878122, 1459955, 15060025, 18855421, 22094463, 27260660; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="threonine dehydratase" /protein_id="NP_390060.1" /db_xref="EnsemblGenomes-Gn:BSU21770" /db_xref="EnsemblGenomes-Tr:CAB14095" /db_xref="GOA:P37946" /db_xref="InterPro:IPR000634" /db_xref="InterPro:IPR001721" /db_xref="InterPro:IPR001926" /db_xref="InterPro:IPR011820" /db_xref="InterPro:IPR036052" /db_xref="SubtiList:BG10673" /db_xref="UniProtKB/Swiss-Prot:P37946" /translation="MKPLLKENSLIQVKDILKAHQNVKDVVIHTPLQRNDRLSERYEC NIYLKREDLQVVRSFKLRGAYHKMKQLSSEQTENGVVCASAGNHAQGVAFSCKHLGIH GKIFMPSTTPRQKVSQVELFGKGFIDIILTGDTFDDAYKSAAECCEAESRTFIHPFDD PDVMAGQGTLAVEILNDIDTEPHFLFASVGGGGLLSGVGTYLKNVSPDTKVIAVEPAG AASYFESNKAGHVVTLDKIDKFVDGAAVKKIGEETFRTLETVVDDILLVPEGKVCTSI LELYNECAVVAEPAGALSVAALDLYKDQIKGKNVVCVVSGGNNDIGRMQEMKERSLIF EGLQHYFIVNFPQRAGALREFLDEVLGPNDDITRFEYTKKNNKSNGPALVGIELQNKA DYGPLIERMNKKPFHYVEVNKDEDLFHLLI*" gene complement(2158367..2159635) /gene="ilvA" /locus_tag="BSU_21770" /old_locus_tag="BSU21770" promotor_-10 complement(2159669..2159688) /Source="Nicolas_upshift_promotors" /id="U1707" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.754245754245754" /psig="0.999000999001" /xcortree=2906 /SigmaFactorBS="gacatagtctgtatttttttaattattaaataaaaataattG TCTTATTttttgaatattCATGTTATAATGGCATATTAaatagggatttaaaacaaga a" /listShort="ilvA, ypmP, S819, scuA, ypmR, ypmS, ypmT" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2159688) /Source="Nicolas_upshifts" /id="U1707" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.754245754245754" /psig="0.999000999001" /xcortree=2906 /SigmaFactorBS="gacatagtctgtatttttttaattattaaataaaaataattG TCTTATTttttgaatattCATGTTATAATGGCATATTAaatagggatttaaaacaaga a" /listShort="ilvA, ypmP, S819, scuA, ypmR, ypmS, ypmT" /GFF_Attribute="listLong" promotor_-35 complement(2159700..2159707) /Source="Nicolas_upshift_promotors" /id="U1707" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.754245754245754" /psig="0.999000999001" /xcortree=2906 /SigmaFactorBS="gacatagtctgtatttttttaattattaaataaaaataattG TCTTATTttttgaatattCATGTTATAATGGCATATTAaatagggatttaaaacaaga a" /listShort="ilvA, ypmP, S819, scuA, ypmR, ypmS, ypmT" /GFF_Attribute="listLong" /label="promotor_-35" misc_feature 2159842..2159861 /Source="Nicolas_upshift_promotors" /id="U1708" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.995004995004995" /psig=1 /xcortree=3088 /SigmaFactorBS="cctgcagagccaagaaaaaagatgatcgtaaaataaagggtg ttttcaaccaaaaggCATGATATAATGAAACCAATtagaaccaaaaggagccaattga t" /listShort="yplP, yplQ, S820" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 2159845 /Source="Nicolas_upshifts" /id="U1708" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.995004995004995" /psig=1 /xcortree=3088 /SigmaFactorBS="cctgcagagccaagaaaaaagatgatcgtaaaataaagggtg ttttcaaccaaaaggCATGATATAATGAAACCAATtagaaccaaaaggagccaattga t" /listShort="yplP, yplQ, S820" /GFF_Attribute="listLong" CDS 2159884..2160879 /gene="silP" /locus_tag="BSU_21780" /old_locus_tag="BSU21780" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:12399512, 16585774, 19763274" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12399512, 16585774, 19763274; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional enhancer involved in BCAA homeostasis" /protein_id="NP_390061.1" /db_xref="EnsemblGenomes-Gn:BSU21780" /db_xref="EnsemblGenomes-Tr:CAB14096" /db_xref="GOA:P54156" /db_xref="InterPro:IPR002078" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR013668" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR036388" /db_xref="SubtiList:BG11619" /db_xref="UniProtKB/Swiss-Prot:P54156" /translation="MNSAPKLNTFQHLIGEHQTFLEAKRIAKQFSLSELPVLITGKIG TGKNHFAHAIHLESSRSNEPFISVNCSTHSEETLIHELFGPNGNTGVFQKAVRGTLFL DDVWRMPASVQAQLLKALDSDTEKPRMICASADRSVEHTFRQDLFYRLNILTLTLPEL SERKSDIPLLTQHFLSNSGQQLLIDPSVFPVLEKHAFEGNVRELKNAADYMAAVSSGG TIQPYDLPPYIRGTIDGKTSKKKAKLLTLMEKAEFLFILETIKVLNEKGEPASRRIIS EHSKNTQTSLTPQQVRSRLDYLEKKDYVTKSRGRAGTKITFEGLSFIETLKNQMI*" gene 2159884..2160879 /gene="silP" /locus_tag="BSU_21780" /old_locus_tag="BSU21780" CDS 2160900..2161541 /gene="yplQ" /locus_tag="BSU_21790" /old_locus_tag="BSU21790" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16585774, 16850406, 19763274; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative membrane hydrolase" /protein_id="NP_390062.1" /db_xref="EnsemblGenomes-Gn:BSU21790" /db_xref="EnsemblGenomes-Tr:CAB14097" /db_xref="GOA:P54175" /db_xref="InterPro:IPR004254" /db_xref="InterPro:IPR005744" /db_xref="SubtiList:BG11620" /db_xref="UniProtKB/Swiss-Prot:P54175" /translation="MFTIKEEIANAITHGIGVLLSIPALVFLIIFAANYGSAWDIVSF TIFGVSMLLLYLSSTLLHSITHKKTKDILEIIDHSAIYVLIAGTYTPFLLGPLKGTLG FTLLVIVWSLALGGIVFKIFFVKRFILLSTFVYLVMGWLMIIAVKPLYASLSGAGFSL LFLGGILYSVGTIFYIWKKIPFHHAIWHSFVLGGSAAMFFCVLFYCVKVPFLS*" gene 2160900..2161541 /gene="yplQ" /locus_tag="BSU_21790" /old_locus_tag="BSU21790" S_feature 2161542..2162643 /Source="Nicolas_S_feature" /locus_tag="new_2295944_2297045" /HighExp="Cold, C30, Sw, BC, G135, LoTm, Fru, C90, BI, S0" /AntisenseName="ypkP" /AntisenseCor="0.28434605181220002" /AntisenseRegPval="-5.7" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S820" CDS complement(2161580..2162200) /gene="ypkP" /locus_tag="BSU_21800" /old_locus_tag="BSU21800" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative 1-acyl-sn-glycerol-3-phosphate acyltransferase" /protein_id="NP_390063.2" /db_xref="EnsemblGenomes-Gn:BSU21800" /db_xref="EnsemblGenomes-Tr:CAB14098" /db_xref="SubtiList:BG11618" /db_xref="UniProtKB/Swiss-Prot:P54174" /translation="MVRYSLLVVYIVYMLLKNMKQLFNQTMLDPRLSYKKQMALVYEQ PKAFLEGCIGISGSVVTIHQPEPIPHGPVLYVHPRLRLAELALIAGYIEEPAGFIANP KVFRLPFIGQWLDRMDVISDGDSEKVYEDVTKQLEKGQSLILSLDGSIDPVELAARYH LPLVMVETKGTDNMQNGSFFKRLKPADIELSFSKAYIPANEKQLRA*" gene complement(2161580..2162200) /gene="ypkP" /locus_tag="BSU_21800" /old_locus_tag="BSU21800" downshifts complement(2161606) /Source="Nicolas_upshifts" /id="D1139" /incds=0 /nref=72 /ntot=241 /MaxReadThrough="1.32187" /MaxDrop="5.02823" /score="16.0584527" /energy="-13.4" /TU="NA" /idTUdmin="U1710" /TUdmin="-21" /isTUend="TRUE" CDS complement(2162201..2162707) /gene="dfrA" /locus_tag="BSU_21810" /old_locus_tag="BSU21810" /EC_number="1.5.1.3" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:2840350, 3918568, 10574451, 12682299, 23944997" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 2840350, 3918568, 10574451, 12682299, 23944997; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="dihydrofolate reductase" /protein_id="NP_390064.1" /db_xref="EnsemblGenomes-Gn:BSU21810" /db_xref="EnsemblGenomes-Tr:CAB14099" /db_xref="GOA:P11045" /db_xref="InterPro:IPR001796" /db_xref="InterPro:IPR012259" /db_xref="InterPro:IPR017925" /db_xref="InterPro:IPR024072" /db_xref="SubtiList:BG10795" /db_xref="UniProtKB/Swiss-Prot:P11045" /translation="MISFIFAMDANRLIGKDNDLPWHLPNDLAYFKKITSGHSIIMGR KTFESIGRPLPNRKNIVVTSAPDSEFQGCTVVSSLKDVLDICSGPEECFVIGGAQLYT DLFPYADRLYMTKIHHEFEGDRHFPEFDESNWKLVSSEQGTKDEKNPYDYEFLMYEKK NSSKAGGF*" gene complement(2162201..2162707) /gene="dfrA" /locus_tag="BSU_21810" /old_locus_tag="BSU21810" CDS complement(2162704..2163498) /gene="thyB" /locus_tag="BSU_21820" /old_locus_tag="BSU21820" /EC_number="2.1.1.45" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:9648749, 10574451, 19732150" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9648749, 10574451, 19732150; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="thymidylate synthase B" /protein_id="NP_390065.1" /db_xref="EnsemblGenomes-Gn:BSU21820" /db_xref="EnsemblGenomes-Tr:CAB14100" /db_xref="GOA:P11044" /db_xref="InterPro:IPR000398" /db_xref="InterPro:IPR020940" /db_xref="InterPro:IPR023451" /db_xref="InterPro:IPR036926" /db_xref="SubtiList:BG10794" /db_xref="UniProtKB/Swiss-Prot:P11044" /translation="MKQYKDFCRHVLEHGEKKGDRTGTGTISTFGYQMRFNLREGFPM LTTKKLHFKSIAHELLWFLKGDTNVRYLQENGVRIWNEWADENGELGPVYGSQWRSWR GADGETIDQISRLIEDIKTNPNSRRLIVSAWNVGEIDKMALPPCHCLFQFYVSDGKLS CQLYQRSADVFLGVPFNIASYALLTMIIAHVTGLEPGEFIHTFGDVHIYQNHIEQVNL QLERDVRPLPQLRFARKVDSIFNFAFEDFIIEDYDPHPHIKGAVSV*" gene complement(2162704..2163498) /gene="thyB" /locus_tag="BSU_21820" /old_locus_tag="BSU21820" CDS complement(2163582..2164115) /gene="ypjQ" /locus_tag="BSU_21830" /old_locus_tag="BSU21830" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 8534098; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative phosphatidylglycerophosphatase" /protein_id="NP_390066.1" /db_xref="EnsemblGenomes-Gn:BSU21830" /db_xref="EnsemblGenomes-Tr:CAB14101" /db_xref="GOA:P54173" /db_xref="InterPro:IPR007686" /db_xref="InterPro:IPR026038" /db_xref="InterPro:IPR036681" /db_xref="PDB:1TLQ" /db_xref="SubtiList:BG11617" /db_xref="UniProtKB/Swiss-Prot:P54173" /translation="MKKYTMNEMVDITKDMLNKRGVMIEDIARIVQKLQEKYNPNLPL SVCMENVEKVLNKREIIHAVLTGLALDQLAEQKLLPEPLQHLVETDEPLYGIDEIIPL SIVNVYGSIGLTNFGYLDKEKIGIIKELDESPDGIHTFLDDIVAALAAAAASRIAHTH QDLQDEEKEQDEKPVVS*" gene complement(2163582..2164115) /gene="ypjQ" /locus_tag="BSU_21830" /old_locus_tag="BSU21830" downshifts complement(2163587) /Source="Nicolas_upshifts" /id="D1140" /incds=0 /nref=17 /ntot=167 /MaxReadThrough="4.91561" /MaxDrop="4.18561" /score="15.5758445" /energy="-9.3" /TU="U1710" /idTUdmin="U1711" /TUdmin=1232 /isTUend="FALSE" promotor_-35 2164045..2164050 /Source="Nicolas_upshift_promotors" /id="U1709" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.996003996003996" /psig="0.996003996003996" /xcortree=1113 /SigmaFactorBS="tatttttcctgaagtttttgaacaatccgtgcaatatcttct ATCATAacgccccgtttgttcaGCATATCCTTTGTTATATCgaccatttcattcattg t" /listShort="S821" /GFF_Attribute="listLong" /label="promotor_-35" S_feature 2164061..2165007 /Source="Nicolas_S_feature" /locus_tag="new_2298463_2299409" /HighExp="S5, S6, S4, S8, S7, S3, B36, BT, B60, T5.0H" /AntisenseName="ypjP" /AntisenseCor="-0.72590712604537599" /AntisenseRegPval="-44.6" /CDS_PredictionProba="0.99932399999999999" /TUshortSig="SigEF" /TUshortPSig="0.996" /TUlongSig="NA" /TUlongPSig="NA" /label="S821" upshifts 2164063 /Source="Nicolas_upshifts" /id="U1709" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.996003996003996" /psig="0.996003996003996" /xcortree=1113 /SigmaFactorBS="tatttttcctgaagtttttgaacaatccgtgcaatatcttct ATCATAacgccccgtttgttcaGCATATCCTTTGTTATATCgaccatttcattcattg t" /listShort="S821" /GFF_Attribute="listLong" promotor_-10 2164067..2164085 /Source="Nicolas_upshift_promotors" /id="U1709" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.996003996003996" /psig="0.996003996003996" /xcortree=1113 /SigmaFactorBS="tatttttcctgaagtttttgaacaatccgtgcaatatcttct ATCATAacgccccgtttgttcaGCATATCCTTTGTTATATCgaccatttcattcattg t" /listShort="S821" /GFF_Attribute="listLong" /label="promotor_-10" CDS complement(2164133..2164744) /gene="ypjP" /locus_tag="BSU_21840" /old_locus_tag="BSU21840" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_390067.1" /db_xref="EnsemblGenomes-Gn:BSU21840" /db_xref="EnsemblGenomes-Tr:CAB14102" /db_xref="GOA:P54172" /db_xref="InterPro:IPR025616" /db_xref="SubtiList:BG11616" /db_xref="UniProtKB/Swiss-Prot:P54172" /translation="MKLWMRKTLVVLFTIVTFGLVSPPAALMADKPSGQPSSLEQNDY TAFYDEHDLYDDESDDRRDPELLFQSYKEQLLDSAEDQSFLKFGSRIAPVIEDDYRKE ILPKIENVISDYLATLQDDEAYQDVVISSMPSAGKTEKIFNVYNRTTGEDLLRFHVRR DHPPHDGYWFNFHYHTAEDGFQSHHELGSIYWDRNTPPNWMSA*" gene complement(2164133..2164744) /gene="ypjP" /locus_tag="BSU_21840" /old_locus_tag="BSU21840" promotor_-10 complement(2164776..2164795) /Source="Nicolas_upshift_promotors" /id="U1710" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.984015984015984" /psig="0.999000999001" /xcortree=2276 /SigmaFactorBS="gcaacgaatctcctaatttgcatatcagtttcatatagtaca TGACTTgcatgttttggaTGTGCTAAAATAAGAGAAACatgacaataaaatagagagg a" /listShort="ypjP, ypjQ, thyB, dfrA, ypkP" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2164795) /Source="Nicolas_upshifts" /id="U1710" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.984015984015984" /psig="0.999000999001" /xcortree=2276 /SigmaFactorBS="gcaacgaatctcctaatttgcatatcagtttcatatagtaca TGACTTgcatgttttggaTGTGCTAAAATAAGAGAAACatgacaataaaatagagagg a" /listShort="ypjP, ypjQ, thyB, dfrA, ypkP" /GFF_Attribute="listLong" promotor_-35 complement(2164808..2164813) /Source="Nicolas_upshift_promotors" /id="U1710" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.984015984015984" /psig="0.999000999001" /xcortree=2276 /SigmaFactorBS="gcaacgaatctcctaatttgcatatcagtttcatatagtaca TGACTTgcatgttttggaTGTGCTAAAATAAGAGAAACatgacaataaaatagagagg a" /listShort="ypjP, ypjQ, thyB, dfrA, ypkP" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 2164964 /Source="Nicolas_upshifts" /id="D1141" /incds=0 /nref=57 /ntot=234 /MaxReadThrough="3.131" /MaxDrop="5.18613" /score="2.81720493" /energy="-15" /TU="U1709" /idTUdmin="U1709" /TUdmin="-527" /isTUend="FALSE" CDS complement(2165004..2165777) /gene="rsmJ" /locus_tag="BSU_21850" /old_locus_tag="BSU21850" /EC_number="2.1.1.242" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 22079366; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative 16S rRNA m(2)G1516 methyltransferase" /protein_id="NP_390068.2" /db_xref="EnsemblGenomes-Gn:BSU21850" /db_xref="EnsemblGenomes-Tr:CAB14103" /db_xref="GOA:P54171" /db_xref="InterPro:IPR007536" /db_xref="InterPro:IPR029063" /db_xref="SubtiList:BG11615" /db_xref="UniProtKB/Swiss-Prot:P54171" /translation="MITTSYRPSEHTIKTAKQLSKELNMPYCGRNKQTVEHLLKSAER DLLVVGKERFELYTKQGAKFFFHPNTAMFRAKRFLQGEKEPMLRAAGLSEGDTFLDCT LGLGSDAIIASMAVGETGSVVGIEKNHLVSVLVRTGLHSWETGIEELQAAMRRIQVKN GDCFEHIKQLPDNSVDVVYFDPMFHEPVETSDGIAPLRDLAEDSVLHEGCINEAVRVA RKSVVLKDHWKSPRFEQFGFNVMKRKTALFHYGVIQTSP*" gene complement(2165004..2165777) /gene="rsmJ" /locus_tag="BSU_21850" /old_locus_tag="BSU21850" downshifts complement(2165039) /Source="Nicolas_upshifts" /id="D1142" /incds=0 /nref=1 /ntot=66 /MaxReadThrough="2.86923" /MaxDrop="2.91228" /score="9.10717118" /energy="-15" /TU="U1711" /idTUdmin="U1711" /TUdmin="-220" /isTUend="FALSE" CDS complement(2165819..2166253) /gene="brxA" /locus_tag="BSU_21860" /old_locus_tag="BSU21860" /function="16.8: Protect" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:19653655, 21749987, 22938038, 24313874, 28301954" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 19653655, 21749987, 22938038, 24313874, 28301954; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="protein disulfide isomerase; bacilliredoxin A (de-bacillithiolation)" /protein_id="NP_390069.1" /db_xref="EnsemblGenomes-Gn:BSU21860" /db_xref="EnsemblGenomes-Tr:CAB14104" /db_xref="InterPro:IPR009474" /db_xref="PDB:3FHK" /db_xref="SubtiList:BG11614" /db_xref="UniProtKB/Swiss-Prot:P54170" /translation="MSMAYEEYMRQLVVPMRRELTGAGFEELTTAEEVENFMEKAEGT TLVVVNSVCGCAAGLARPAATQAVLQNDKTPDNTVTVFAGQDKEATAKMREYFTGQEP SSPSMALLKGKEVVHFIPRHEIEGHDMEEIMKNLTAAFDAHC*" gene complement(2165819..2166253) /gene="brxA" /locus_tag="BSU_21860" /old_locus_tag="BSU21860" downshifts complement(2165831) /Source="Nicolas_upshifts" /id="D1143" /incds=0 /nref=9 /ntot=210 /MaxReadThrough="5.2935" /MaxDrop="3.1992" /score="21.0933404" /energy="-9.7" /TU="U1711,U1712" /idTUdmin="U1712" /TUdmin="-462" /isTUend="FALSE" promotor_-10 complement(2166282..2166301) /Source="Nicolas_upshift_promotors" /id="U1711" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.972027972027972" /psig="0.997002997002997" /xcortree=1933 /SigmaFactorBS="ggggacactttcttttattttaaggcgtgaaCATTTGAAatc cggccctctcTATAGTATCCTTTACTTCAGatgaaggatactagagggggcttttttt a" /listShort="yphP, ypiP" /listLong="ypjP, ypjQ, thyB, dfrA, ypkP" /label="promotor_-10" upshifts complement(2166293) /Source="Nicolas_upshifts" /id="U1711" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.972027972027972" /psig="0.997002997002997" /xcortree=1933 /SigmaFactorBS="ggggacactttcttttattttaaggcgtgaaCATTTGAAatc cggccctctcTATAGTATCCTTTACTTCAGatgaaggatactagagggggcttttttt a" /listShort="yphP, ypiP" /listLong="ypjP, ypjQ, thyB, dfrA, ypkP" S_feature complement(2166295..2166359) /Source="Nicolas_S_feature" /locus_tag="new_2300697_2300761_c" /HighExp="Sw, S1, BC, Gly, HiOs, HiTm, GM-0.1, UNK1, Fru, MG 60" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.997" /TUlongSig="NA" /TUlongPSig="NA" /label="S822" promotor_-35 complement(2166315..2166322) /Source="Nicolas_upshift_promotors" /id="U1711" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.972027972027972" /psig="0.997002997002997" /xcortree=1933 /SigmaFactorBS="ggggacactttcttttattttaaggcgtgaaCATTTGAAatc cggccctctcTATAGTATCCTTTACTTCAGatgaaggatactagagggggcttttttt a" /listShort="yphP, ypiP" /listLong="ypjP, ypjQ, thyB, dfrA, ypkP" /label="promotor_-35" downshifts complement(2166338) /Source="Nicolas_upshifts" /id="D1144" /incds=0 /nref=32 /ntot=128 /MaxReadThrough="5.73826" /MaxDrop="4.95094" /score="26.9702838" /energy="-25.8" /TU="U1712" /idTUdmin="U1713" /TUdmin="-1" /isTUend="TRUE" CDS complement(2166360..2168036) /gene="ilvD" /locus_tag="BSU_21870" /old_locus_tag="BSU21870" /EC_number="4.2.1.9" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:12193635, 12618455, 15060025, 24163341" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12193635, 12618455, 15060025, 24163341; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="dihydroxy-acid dehydratase" /protein_id="NP_390070.2" /db_xref="EnsemblGenomes-Gn:BSU21870" /db_xref="EnsemblGenomes-Tr:CAB14105" /db_xref="GOA:P51785" /db_xref="InterPro:IPR000581" /db_xref="InterPro:IPR004404" /db_xref="InterPro:IPR015928" /db_xref="InterPro:IPR020558" /db_xref="SubtiList:BG11532" /db_xref="UniProtKB/Swiss-Prot:P51785" /translation="MAELRSNMITQGIDRAPHRSLLRAAGVKEEDFGKPFIAVCNSYI DIVPGHVHLQEFGKIVKEAIREAGGVPFEFNTIGVDDGIAMGHIGMRYSLPSREIIAD SVETVVSAHWFDGMVCIPNCDKITPGMLMAAMRINIPTIFVSGGPMAAGRTSDGRKIS LSSVFEGVGAYQAGKINENELQELEQFGCPTCGSCSGMFTANSMNCLSEALGLALPGN GTILATSPERKEFVRKSAAQLMETIRKDIKPRDIVTVKAIDNAFALDMALGGSTNTVL HTLALANEAGVEYSLERINEVAERVPHLAKLAPASDVFIEDLHEAGGVSAALNELSKK EGALHLDALTVTGKTLGETIAGHEVKDYDVIHPLDQPFTEKGGLAVLFGNLAPDGAII KTGGVQNGITRHEGPAVVFDSQDEALDGIINRKVKEGDVVIIRYEGPKGGPGMPEMLA PTSQIVGMGLGPKVALITDGRFSGASRGLSIGHVSPEAAEGGPLAFVENGDHIIVDIE KRILDVQVPEEEWEKRKANWKGFEPKVKTGYLARYSKLVTSANTGGIMKI*" gene complement(2166360..2168036) /gene="ilvD" /locus_tag="BSU_21870" /old_locus_tag="BSU21870" S_feature complement(2168037..2168227) /Source="Nicolas_S_feature" /locus_tag="new_2302439_2302629_c" /HighExp="S1, T-5.40H, MG 45, HiOs, T-4.40H, MG 120, UNK1, MG 25, MG-0.2, GM-0.2" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="0.997, 0.97" /TUlongSig="SigH" /TUlongPSig=1 /label="S823" promotor_-10 complement(2168216..2168235) /Source="Nicolas_upshift_promotors" /id="U1712" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.555444555444555" /psig="0.997002997002997" /xcortree=2910 /SigmaFactorBS="gaattcactttttataaaaattatttcgaatattGTTGaaaa atatccgaaaACTATTTATAGTAAGTAACAatattaatagttggagggttcaaatcga a" /listShort="S823, ilvD, S822, yphP, ypiP" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2168227) /Source="Nicolas_upshifts" /id="U1712" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.555444555444555" /psig="0.997002997002997" /xcortree=2910 /SigmaFactorBS="gaattcactttttataaaaattatttcgaatattGTTGaaaa atatccgaaaACTATTTATAGTAAGTAACAatattaatagttggagggttcaaatcga a" /listShort="S823, ilvD, S822, yphP, ypiP" /GFF_Attribute="listLong" promotor_-35 complement(2168250..2168253) /Source="Nicolas_upshift_promotors" /id="U1712" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.555444555444555" /psig="0.997002997002997" /xcortree=2910 /SigmaFactorBS="gaattcactttttataaaaattatttcgaatattGTTGaaaa atatccgaaaACTATTTATAGTAAGTAACAatattaatagttggagggttcaaatcga a" /listShort="S823, ilvD, S822, yphP, ypiP" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2168325..2169458) /gene="ypgR" /locus_tag="BSU_21880" /old_locus_tag="BSU21880" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative lyase or scaffold" /protein_id="NP_390071.1" /db_xref="EnsemblGenomes-Gn:BSU21880" /db_xref="EnsemblGenomes-Tr:CAB14106" /db_xref="InterPro:IPR004155" /db_xref="InterPro:IPR014824" /db_xref="InterPro:IPR016024" /db_xref="InterPro:IPR025989" /db_xref="InterPro:IPR036498" /db_xref="SubtiList:BG11613" /db_xref="UniProtKB/Swiss-Prot:P54169" /translation="MKIKSIEPTPSPNTMKVILTEELPAGKSNNYKPEQAEGAPLVIA EILKIDGVKGVYHVADFLAVERNARYDWKDILPQVRTAFGMESAESAEENRSDQESFG EVKVFVQMFSGIPMQVKLTDGEREERFGLPERFQQAILKLRSEASNVVFERAWKEQGV RFGDFDEIGHDVTEELQAAYSDERLKRLTEAAAQGKGEAKQAVQRKAYKVTLDMLDDE DWKKRYAHLEQMDPKEEDIPVLQKALDDPKVSIRRQAVVYLGMIETPDVLPLLYKALE DKAVSVRRTAGDCLSDIGDPQAIPAMIKSLSDSSKLVRWRAAMFLYEVGDESAIEALR AAEDDPEFEVSLQVKMALERIEHGEEAKGSVWKQMTESRKKGE*" gene complement(2168325..2169458) /gene="ypgR" /locus_tag="BSU_21880" /old_locus_tag="BSU21880" downshifts complement(2168341) /Source="Nicolas_upshifts" /id="D1145" /incds=0 /nref=193 /ntot=249 /MaxReadThrough="5.33526" /MaxDrop="6.88149" /score="18.2078317" /energy="-8.7" /TU="U1713" /idTUdmin="U1714" /TUdmin="-2" /isTUend="TRUE" misc_feature complement(2169480..2169499) /Source="Nicolas_upshift_promotors" /id="U1713" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.618381618381618" /psig="0.97002997002997" /xcortree=1972 /SigmaFactorBS="ccgggattgatgccgaaacgtcgtaatagaaggcttggagcg acTATGATAGAATAAGTCACAGatatgctataggaggacgatcatgaagataaaatca a" /listShort="ypgR, S823, ilvD" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(2169483) /Source="Nicolas_upshifts" /id="U1713" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.618381618381618" /psig="0.97002997002997" /xcortree=1972 /SigmaFactorBS="ccgggattgatgccgaaacgtcgtaatagaaggcttggagcg acTATGATAGAATAAGTCACAGatatgctataggaggacgatcatgaagataaaatca a" /listShort="ypgR, S823, ilvD" /GFF_Attribute="listLong" CDS complement(2169518..2170135) /gene="hdhQ" /locus_tag="BSU_21890" /old_locus_tag="BSU21890" /EC_number="3.6.1.-" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:25005104, 27062940" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 25005104, 27062940; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="Mn(2+)-dependent (deoxy)ribonucleoside pyrophosphohydrolase" /protein_id="NP_390072.1" /db_xref="EnsemblGenomes-Gn:BSU21890" /db_xref="EnsemblGenomes-Tr:CAB14107" /db_xref="InterPro:IPR003607" /db_xref="InterPro:IPR006674" /db_xref="SubtiList:BG11612" /db_xref="UniProtKB/Swiss-Prot:P54168" /translation="MKELKQAEQIRTWVQSILTDESSGHDWHHVSRVADLAAYIGEKE KADLFIVETAALVHDLIDVKLPDTVRLSVSEVYDQLVFFGVGKENADRVIHIITRMSF RDRGKLAKEPLSIEGKAVQDADRLDAIGAVGIARAFMFAGAKGHGLYGDEQSAYAHFF HKLLRLKDMMNTDTARELAEERHNFMLQFVRQLEKDIPGIDAETS*" gene complement(2169518..2170135) /gene="hdhQ" /locus_tag="BSU_21890" /old_locus_tag="BSU21890" CDS complement(2170151..2170633) /gene="bsaA" /locus_tag="BSU_21900" /old_locus_tag="BSU21900" /EC_number="1.11.1.-" /function="16.8: Protect" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2b: Function from indirect experimental evidences (e.g. phenotypes); PubMedId: 14563871, 14617062, 21749987, 25852656; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="bacillithiol peroxidase" /protein_id="NP_390073.1" /db_xref="EnsemblGenomes-Gn:BSU21900" /db_xref="EnsemblGenomes-Tr:CAB14108" /db_xref="GOA:P52035" /db_xref="InterPro:IPR000889" /db_xref="InterPro:IPR029759" /db_xref="InterPro:IPR029760" /db_xref="InterPro:IPR036249" /db_xref="SubtiList:BG11530" /db_xref="UniProtKB/Swiss-Prot:P52035" /translation="MSIYHMKVRTITGKDMTLQPFAGKVLMIVNTASKCGFTSQLKQL QELYDTYQQEGLEILGFPCNQFMNQEPGEEADIQEFCETNYGVTFPMFSKVDVNGKNA HPLFVYLTEHAKGMLGTKAIKWNFTKFIVDRNGEIVGRYSPNTNPKELEDDIVKLLEQ *" gene complement(2170151..2170633) /gene="bsaA" /locus_tag="BSU_21900" /old_locus_tag="BSU21900" S_feature complement(2170634..2170781) /Source="Nicolas_S_feature" /locus_tag="new_2305036_2305183_c" /HighExp="S2, HiOs, S1, Etha, T2.30H, T3.0H, Lbtran, M0t90, T2.0H, SMMPr" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigH" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S824" promotor_-10 complement(2170772..2170790) /Source="Nicolas_upshift_promotors" /id="U1714" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp=1 /psig=1 /xcortree=3200 /SigmaFactorBS="tggtttcacagtaaaatgattttcaaagatgtaAGAGGGAAT tgtaatgtttTATAGAATGATAAGATAAAaaacgagccatatgaattgataatgaact g" /listShort="S824, bsaA, ypgQ, ypgR" /listLong="S823, ilvD" /label="promotor_-10" upshifts complement(2170782) /Source="Nicolas_upshifts" /id="U1714" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp=1 /psig=1 /xcortree=3200 /SigmaFactorBS="tggtttcacagtaaaatgattttcaaagatgtaAGAGGGAAT tgtaatgtttTATAGAATGATAAGATAAAaaacgagccatatgaattgataatgaact g" /listShort="S824, bsaA, ypgQ, ypgR" /listLong="S823, ilvD" promotor_-35 complement(2170801..2170809) /Source="Nicolas_upshift_promotors" /id="U1714" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp=1 /psig=1 /xcortree=3200 /SigmaFactorBS="tggtttcacagtaaaatgattttcaaagatgtaAGAGGGAAT tgtaatgtttTATAGAATGATAAGATAAAaaacgagccatatgaattgataatgaact g" /listShort="S824, bsaA, ypgQ, ypgR" /listLong="S823, ilvD" /label="promotor_-35" promotor_-35 2170835..2170844 /Source="Nicolas_upshift_promotors" /id="U1715" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1652 /SigmaFactorBS="caattccctcttacatctttgaaaatcattttactgTGAAAC CAAAaggcgtgtcagtGCGTTTTATTTAAAGAgttttctgttgtttccccctcaacac g" /listShort="S825, metA, S826, ugtP" /listLong="S828, cspD, S829, ypzA" /label="promotor_-35" promotor_-10 2170857..2170872 /Source="Nicolas_upshift_promotors" /id="U1715" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1652 /SigmaFactorBS="caattccctcttacatctttgaaaatcattttactgTGAAAC CAAAaggcgtgtcagtGCGTTTTATTTAAAGAgttttctgttgtttccccctcaacac g" /listShort="S825, metA, S826, ugtP" /listLong="S828, cspD, S829, ypzA" /label="promotor_-10" S_feature 2170859..2170945 /Source="Nicolas_S_feature" /locus_tag="new_2305261_2305347" /HighExp="Salt, T-0.40H, T-1.10H, Heat, T-1.40H, H2O2, T0.0H, Paraq, T0.30H, HiTm" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigWXY" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S825" upshifts 2170859 /Source="Nicolas_upshifts" /id="U1715" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1652 /SigmaFactorBS="caattccctcttacatctttgaaaatcattttactgTGAAAC CAAAaggcgtgtcagtGCGTTTTATTTAAAGAgttttctgttgtttccccctcaacac g" /listShort="S825, metA, S826, ugtP" /listLong="S828, cspD, S829, ypzA" promotor_-35 2170908..2170915 /Source="Nicolas_upshift_promotors" /id="U1716" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.612387612387612" /psig="0.995004995004995" /xcortree=2257 /SigmaFactorBS="ccccctcaacacgtatagataGATTGAAAattggcgtgaaaa tTCCTATAATGAAGAAAATTAaacggggaaataatggaggtggcacgttgcctattaa t" /listShort="metA, S826, ugtP" /listLong="S828, cspD, S829, ypzA" /label="promotor_-35" promotor_-10 2170930..2170949 /Source="Nicolas_upshift_promotors" /id="U1716" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.612387612387612" /psig="0.995004995004995" /xcortree=2257 /SigmaFactorBS="ccccctcaacacgtatagataGATTGAAAattggcgtgaaaa tTCCTATAATGAAGAAAATTAaacggggaaataatggaggtggcacgttgcctattaa t" /listShort="metA, S826, ugtP" /listLong="S828, cspD, S829, ypzA" /label="promotor_-10" upshifts 2170947 /Source="Nicolas_upshifts" /id="U1716" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.612387612387612" /psig="0.995004995004995" /xcortree=2257 /SigmaFactorBS="ccccctcaacacgtatagataGATTGAAAattggcgtgaaaa tTCCTATAATGAAGAAAATTAaacggggaaataatggaggtggcacgttgcctattaa t" /listShort="metA, S826, ugtP" /listLong="S828, cspD, S829, ypzA" CDS 2170976..2171881 /gene="metAA" /locus_tag="BSU_21910" /old_locus_tag="BSU21910" /EC_number="2.3.1.31" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:5001847, 10939241, 11832514, 17056751, 18216013, 28581482" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 5001847, 10939241, 11832514, 17056751, 18216013, 28581482; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="homoserine O-acetyltransferase" /protein_id="NP_390074.2" /db_xref="EnsemblGenomes-Gn:BSU21910" /db_xref="EnsemblGenomes-Tr:CAB14109" /db_xref="GOA:P54167" /db_xref="InterPro:IPR005697" /db_xref="InterPro:IPR029062" /db_xref="InterPro:IPR033752" /db_xref="SubtiList:BG11534" /db_xref="UniProtKB/Swiss-Prot:P54167" /translation="MPINIPTHLPAKQVLESEHIFVMDESRAFHQDIRPQKIIILNLM PKKIQTETQLLRLLGNSPLQVHFTFLIPSTHTPKNTAREHLDEFYTTFSNIRHKRFDG MIITGAPIEHLAFEEVSYWEELKEIMEWSKTNVTSTLHICWGAQAGLYYHYGVEKIQM PKKIFGVFEHTVLSKHERLVRGFDELYYVPHSRHTDINMEQLQAVPELNILTASKEAG VCLIVSKDEKQVFLTGHPEYDTNTLLQEYERDLERNLSTVEAPKHYFAKGSNEPVNRW KAHATLLFMNWLNYYVYQETPYEWD*" gene 2170976..2171881 /gene="metAA" /locus_tag="BSU_21910" /old_locus_tag="BSU21910" misc_feature 2171916..2171935 /Source="Nicolas_upshift_promotors" /id="U1717" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.982017982017982" /psig="0.999000999001" /xcortree=2287 /SigmaFactorBS="gaatgggactaatttttctttttttagtgatacgctgagcaa aaaaTATGATAAAATACATCTGATtcagtctgcgtataacaaaaatttaaaatactgg a" /listShort="S826, ugtP" /listLong="S828, cspD, S829, ypzA" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 2171930 /Source="Nicolas_upshifts" /id="U1717" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.982017982017982" /psig="0.999000999001" /xcortree=2287 /SigmaFactorBS="gaatgggactaatttttctttttttagtgatacgctgagcaa aaaaTATGATAAAATACATCTGATtcagtctgcgtataacaaaaatttaaaatactgg a" /listShort="S826, ugtP" /listLong="S828, cspD, S829, ypzA" S_feature 2171931..2172111 /Source="Nicolas_S_feature" /locus_tag="new_2306333_2306513" /HighExp="Heat, HiTm, LoTm, C90, M9-stat, HiOs, SMM, UNK1, MG 25, S3" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA, SigWXY" /TUshortPSig="0.999, 0.995, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S826" CDS 2172112..2173260 /gene="ugtP" /locus_tag="BSU_21920" /old_locus_tag="BSU21920" /EC_number="2.4.1.315" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:11344159, 17209021, 17662947, 9720862, 18820022, 22362028, 22931116, 27684739" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11344159, 17209021, 17662947, 9720862, 18820022, 22362028, 22931116, 27684739; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="UDP-glucose diacylglyceroltransferase" /protein_id="NP_390075.1" /db_xref="EnsemblGenomes-Gn:BSU21920" /db_xref="EnsemblGenomes-Tr:CAB14110" /db_xref="GOA:P54166" /db_xref="InterPro:IPR001296" /db_xref="InterPro:IPR009695" /db_xref="InterPro:IPR023589" /db_xref="SubtiList:BG11611" /db_xref="UniProtKB/Swiss-Prot:P54166" /translation="MNTNKRVLILTANYGNGHVQVAKTLYEQCVRLGFQHVTVSNLYQ ESNPIVSEVTQYLYLKSFSIGKQFYRLFYYGVDKIYNKRKFNIYFKMGNKRLGELVDE HQPDIIINTFPMIVVPEYRRRTGRVIPTFNVMTDFCLHKIWVHENVDKYYVATDYVKE KLLEIGTHPSNVKITGIPIRPQFEESMPVGPIYKKYNLSPNKKVLLIMAGAHGVLKNV KELCENLVKDDQVQVVVVCGKNTALKESLSALEAENGDKLKVLGYVERIDELFRITDC MITKPGGITLTEATAIGVPVILYKPVPGQEKENANFFEDRGAAIVVNRHEEILESVTS LLADEDTLHRMKKNIKDLHLANSSEVILEDILKESEMMTAKQKAKVLS*" gene 2172112..2173260 /gene="ugtP" /locus_tag="BSU_21920" /old_locus_tag="BSU21920" S_feature complement(2172281..2173310) /Source="Nicolas_S_feature" /locus_tag="new_2306683_2307712_c" /HighExp="S8, S7, S6, C30, Lbstat, T0.30H, C90, BT, G135, Fru" /AntisenseName="ugtP" /AntisenseCor="-0.328222465122327" /AntisenseRegPval="-7.4" /CDS_PredictionProba="NA" /TUshortSig="SigK" /TUshortPSig="0.995" /TUlongSig="NA" /TUlongPSig="NA" /label="S827" downshifts 2173256 /Source="Nicolas_upshifts" /id="D1146" /incds=0 /nref=77 /ntot=240 /MaxReadThrough="4.0787" /MaxDrop="4.20549" /score="21.6989702" /energy="-12.1" /TU="U1715,U1717" /idTUdmin="U1716" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(2173292..2173311) /Source="Nicolas_upshift_promotors" /id="U1718" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.995004995004995" /psig="0.995004995004995" /xcortree=1392 /SigmaFactorBS="cttatttttcaaaagaagggcaagttccataaaaaaATGTAA CCGcttttattgatggcTGAATATAAATAAAAAGAGCacacgattttcgtatgctctc a" /listShort="S827" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2173310) /Source="Nicolas_upshifts" /id="U1718" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.995004995004995" /psig="0.995004995004995" /xcortree=1392 /SigmaFactorBS="cttatttttcaaaagaagggcaagttccataaaaaaATGTAA CCGcttttattgatggcTGAATATAAATAAAAAGAGCacacgattttcgtatgctctc a" /listShort="S827" /GFF_Attribute="listLong" promotor_-35 complement(2173326..2173334) /Source="Nicolas_upshift_promotors" /id="U1718" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.995004995004995" /psig="0.995004995004995" /xcortree=1392 /SigmaFactorBS="cttatttttcaaaagaagggcaagttccataaaaaaATGTAA CCGcttttattgatggcTGAATATAAATAAAAAGAGCacacgattttcgtatgctctc a" /listShort="S827" /GFF_Attribute="listLong" /label="promotor_-35" CDS 2173341..2173487 /locus_tag="BSU_21925" /old_locus_tag="BSU21925" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_009513973.1" /translation="MELALLLKNKPFRNLTGAPRWCIVEPSFNNESKLDDDKIFFSTW VLQY*" gene 2173341..2173487 /locus_tag="BSU_21925" /old_locus_tag="BSU21925" promotor_-35 2173380..2173387 /Source="Nicolas_upshift_promotors" /id="U1719" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.829170829170829" /psig="0.999000999001" /xcortree=3102 /SigmaFactorBS="ccttcttttgaaaaataagccgtttcgcAACTTGACgggtgc tcccagaTGGTGTATAGTTGAACCATCatttaacaatgaatcaaagttagatgatgac a" /listShort="S828, cspD, S829, ypzA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2173401..2173420 /Source="Nicolas_upshift_promotors" /id="U1719" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.829170829170829" /psig="0.999000999001" /xcortree=3102 /SigmaFactorBS="ccttcttttgaaaaataagccgtttcgcAACTTGACgggtgc tcccagaTGGTGTATAGTTGAACCATCatttaacaatgaatcaaagttagatgatgac a" /listShort="S828, cspD, S829, ypzA" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 2173412..2173502 /Source="Nicolas_S_feature" /locus_tag="new_2307814_2307904" /HighExp="C90, T5.0H, T3.30H, T3.0H, HiOs, Salt, LoTm, T-3.40H, S3, T-0.40H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.999" /TUlongSig="SigA, SigA, SigWXY" /TUlongPSig="0.999, 0.995, 1" /label="S828" upshifts 2173412 /Source="Nicolas_upshifts" /id="U1719" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.829170829170829" /psig="0.999000999001" /xcortree=3102 /SigmaFactorBS="ccttcttttgaaaaataagccgtttcgcAACTTGACgggtgc tcccagaTGGTGTATAGTTGAACCATCatttaacaatgaatcaaagttagatgatgac a" /listShort="S828, cspD, S829, ypzA" /GFF_Attribute="listLong" CDS 2173503..2173703 /gene="cspD" /locus_tag="BSU_21930" /old_locus_tag="BSU21930" /function="16.13: Shape" /function="16.8: Protect" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:9920884, 16352840" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9920884, 16352840; Product type f: factor" /codon_start=1 /transl_table=11 /product="cold-shock protein, molecular chaperone, RNA-helicase co-factor" /protein_id="NP_390076.1" /db_xref="EnsemblGenomes-Gn:BSU21930" /db_xref="EnsemblGenomes-Tr:CAB14111" /db_xref="GOA:P51777" /db_xref="InterPro:IPR002059" /db_xref="InterPro:IPR011129" /db_xref="InterPro:IPR012156" /db_xref="InterPro:IPR012340" /db_xref="InterPro:IPR019844" /db_xref="SubtiList:BG11531" /db_xref="UniProtKB/Swiss-Prot:P51777" /translation="MQNGKVKWFNNEKGFGFIEVEGGDDVFVHFTAIEGDGYKSLEEG QEVSFEIVEGNRGPQASNVVKL*" gene 2173503..2173703 /gene="cspD" /locus_tag="BSU_21930" /old_locus_tag="BSU21930" downshifts 2173718 /Source="Nicolas_upshifts" /id="D1147" /incds=0 /nref=257 /ntot=269 /MaxReadThrough="5.19931" /MaxDrop="8.09346" /score="9.24662311" /energy="-15.6" /TU="U1719" /idTUdmin="U1715" /TUdmin=308 /isTUend="FALSE" CDS complement(2173755..2173937) /gene="degR" /locus_tag="BSU_21940" /old_locus_tag="BSU21940" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:16625836, 19251843, 22720735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16625836, 19251843, 22720735; Product type f: factor" /codon_start=1 /transl_table=11 /product="activator of degradative enzymes (aprE, nprE, sacB) production or activity" /protein_id="NP_390077.1" /db_xref="EnsemblGenomes-Gn:BSU21940" /db_xref="EnsemblGenomes-Tr:CAB14112" /db_xref="GOA:P68731" /db_xref="SubtiList:BG10699" /db_xref="UniProtKB/Swiss-Prot:P68731" /translation="MDDKDLKLILHKTFIEIYSDLEELADIAKKGKPSMEKYVEEIEQ RCKQNILAIEIQMKIK*" gene complement(2173755..2173937) /gene="degR" /locus_tag="BSU_21940" /old_locus_tag="BSU21940" S_feature 2173763..2174068 /Source="Nicolas_S_feature" /locus_tag="new_2308165_2308470" /HighExp="Cold, LoTm, T4.0H, T3.30H, Pyr, T5.0H, Gly, T3.0H, S0, C30" /AntisenseName="degR" /AntisenseCor="-0.145220711637392" /AntisenseRegPval="-1.8" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.999" /TUlongSig="SigA, SigA, SigWXY" /TUlongPSig="0.999, 0.995, 1" /label="S829" downshifts complement(2173772) /Source="Nicolas_upshifts" /id="D1148" /incds=0 /nref=133 /ntot=216 /MaxReadThrough="3.75638" /MaxDrop="5.32427" /score="16.1392275" /energy="-7.3" /TU="U1720" /idTUdmin="U1720" /TUdmin="-22" /isTUend="TRUE" promotor_-10 complement(2173998..2174016) /Source="Nicolas_upshift_promotors" /id="U1720" /multdbtbs="SigD" /comp="M10" /sig="SigD" /pcomp="0.986013986013986" /psig="0.986013986013986" /xcortree=2841 /SigmaFactorBS="acaaaaaacacctccgccattattttgcagagtttttttgaa atttatgtaccaaaatAGAAAAGaaaataaaaataaGCCGATATAACTATTGAACcag a" /listShort="degR" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 complement(2174030..2174036) /Source="Nicolas_upshift_promotors" /id="U1720" /multdbtbs="SigD" /comp="M10" /sig="SigD" /pcomp="0.986013986013986" /psig="0.986013986013986" /xcortree=2841 /SigmaFactorBS="acaaaaaacacctccgccattattttgcagagtttttttgaa atttatgtaccaaaatAGAAAAGaaaataaaaataaGCCGATATAACTATTGAACcag a" /listShort="degR" /GFF_Attribute="listLong" /label="promotor_-35" upshifts complement(2174034) /Source="Nicolas_upshifts" /id="U1720" /multdbtbs="SigD" /comp="M10" /sig="SigD" /pcomp="0.986013986013986" /psig="0.986013986013986" /xcortree=2841 /SigmaFactorBS="acaaaaaacacctccgccattattttgcagagtttttttgaa atttatgtaccaaaatAGAAAAGaaaataaaaataaGCCGATATAACTATTGAACcag a" /listShort="degR" /GFF_Attribute="listLong" promotor_-35 2174044..2174050 /Source="Nicolas_upshift_promotors" /id="U1721" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=913 /SigmaFactorBS="tatcggcttatttttattttcttttctattttggTACATAAa tttcaaaaaaactCTGCAAAATAATggcggaggtgttttttgtgacttcagaatttca t" /listShort="ypzA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2174065..2174076 /Source="Nicolas_upshift_promotors" /id="U1721" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=913 /SigmaFactorBS="tatcggcttatttttattttcttttctattttggTACATAAa tttcaaaaaaactCTGCAAAATAATggcggaggtgttttttgtgacttcagaatttca t" /listShort="ypzA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2174070 /Source="Nicolas_upshifts" /id="U1721" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=913 /SigmaFactorBS="tatcggcttatttttattttcttttctattttggTACATAAa tttcaaaaaaactCTGCAAAATAATggcggaggtgttttttgtgacttcagaatttca t" /listShort="ypzA" /GFF_Attribute="listLong" CDS 2174093..2174362 /gene="ypzA" /locus_tag="BSU_21950" /old_locus_tag="BSU21950" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 12562816, 22882546; Product type s: structure" /codon_start=1 /transl_table=11 /product="putative spore coat protein" /protein_id="NP_390078.1" /db_xref="EnsemblGenomes-Gn:BSU21950" /db_xref="EnsemblGenomes-Tr:CAB14113" /db_xref="InterPro:IPR020314" /db_xref="SubtiList:BG13764" /db_xref="UniProtKB/Swiss-Prot:O32007" /translation="MTSEFHNEDQTGFTDKRQLELAVETAQKTTGAATRGQSKTLVDS AYQAIEDARELSQSEELAALDDPEFVKQQQQLLDDSEHQLDEFKE*" gene 2174093..2174362 /gene="ypzA" /locus_tag="BSU_21950" /old_locus_tag="BSU21950" downshifts 2174217 /Source="Nicolas_upshifts" /id="D1149" /incds=1 /nref=3 /ntot=82 /MaxReadThrough="6.79633" /MaxDrop="4.11501" /score="22.0113838" /energy="-7.3" /TU="U1719,U1721" /idTUdmin="U1719" /TUdmin="-117" /isTUend="FALSE" downshifts 2174345 /Source="Nicolas_upshifts" /id="D1150" /incds=0 /nref=18 /ntot=94 /MaxReadThrough="2.31821" /MaxDrop="6.65627" /score="22.0113838" /energy="-7.3" /TU="NA" /idTUdmin="U1719" /TUdmin=11 /isTUend="TRUE" CDS complement(2174390..2174572) /gene="ypeQ" /locus_tag="BSU_21960" /old_locus_tag="BSU21960" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 12562816" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_390079.1" /db_xref="EnsemblGenomes-Gn:BSU21960" /db_xref="EnsemblGenomes-Tr:CAB14114" /db_xref="InterPro:IPR019718" /db_xref="SubtiList:BG11610" /db_xref="UniProtKB/Swiss-Prot:P54165" /translation="MDKKMIFKELTELHDEYCKDCFIKKQFRKEFGKTYAHSFCINKC TVGEKLKQYGDVLTNH*" gene complement(2174390..2174572) /gene="ypeQ" /locus_tag="BSU_21960" /old_locus_tag="BSU21960" downshifts complement(2174410) /Source="Nicolas_upshifts" /id="D1151" /incds=0 /nref=5 /ntot=102 /MaxReadThrough="2.77117" /MaxDrop="4.29218" /score="16.1392275" /energy="-7.3" /TU="NA" /idTUdmin="U1723" /TUdmin=0 /isTUend="TRUE" CDS complement(2174565..2175245) /gene="ypeP" /locus_tag="BSU_21970" /old_locus_tag="BSU21970" /EC_number="3.1.-.-" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:12562816, 17905985, 22720735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12562816, 17905985, 22720735; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="ribonuclease" /protein_id="NP_390080.2" /db_xref="EnsemblGenomes-Gn:BSU21970" /db_xref="EnsemblGenomes-Tr:CAB14115" /db_xref="GOA:P54164" /db_xref="InterPro:IPR002156" /db_xref="InterPro:IPR012337" /db_xref="InterPro:IPR036397" /db_xref="SubtiList:BG11609" /db_xref="UniProtKB/Swiss-Prot:P54164" /translation="MKLRPHLKIEAKGTGSVSFFSEDWLTAQQARTFARELGRFPYMK ELEFEDEKGGSWTLKELEKLTEELAQEPDDITVYFDGSFDKESELAGLGIVIYYSLGG TRHRLRKNKSFRLKTNNEAEYAALYEAIREVRELGASRNSITIKGDSLVVLNQLDGSW PCYDPSHNEWLDKIEALLESLKLTPTYETIQRKDNQEADGLAKKILSHQFVESHTKLD RNGDDDIG*" gene complement(2174565..2175245) /gene="ypeP" /locus_tag="BSU_21970" /old_locus_tag="BSU21970" S_feature complement(2175246..2175383) /Source="Nicolas_S_feature" /locus_tag="new_2309648_2309785_c" /HighExp="S5, S4, S6, S8, S7, S3, T5.0H, T4.0H, BT, Pyr" /AntisenseName="ypdP" /AntisenseCor="-0.65324924042743404" /AntisenseRegPval="-33.4" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigH" /TUshortPSig="0.92, 0.564" /TUlongSig="NA" /TUlongPSig="NA" /label="S830" promotor_-35 2175262..2175267 /Source="Nicolas_upshift_promotors" /id="U1722" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.985014985014985" /psig="0.999000999001" /xcortree=2280 /SigmaFactorBS="caaatgcggtctgagcttcattacaatcaccttaccaTTCAT TagttgccgggctTATGCTATAATCAAACCAATcttaccccggaaaggaagctttttc a" /listShort="ypdP, ypdQ, sspL, S832" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2175280..2175299 /Source="Nicolas_upshift_promotors" /id="U1722" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.985014985014985" /psig="0.999000999001" /xcortree=2280 /SigmaFactorBS="caaatgcggtctgagcttcattacaatcaccttaccaTTCAT TagttgccgggctTATGCTATAATCAAACCAATcttaccccggaaaggaagctttttc a" /listShort="ypdP, ypdQ, sspL, S832" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2175285 /Source="Nicolas_upshifts" /id="U1722" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.985014985014985" /psig="0.999000999001" /xcortree=2280 /SigmaFactorBS="caaatgcggtctgagcttcattacaatcaccttaccaTTCAT TagttgccgggctTATGCTATAATCAAACCAATcttaccccggaaaggaagctttttc a" /listShort="ypdP, ypdQ, sspL, S832" /GFF_Attribute="listLong" CDS 2175328..2176017 /gene="queP" /locus_tag="BSU_21980" /old_locus_tag="BSU21980" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 28208705; Product type t : transporter" /codon_start=1 /transl_table=11 /product="preQ0 transporter (promiscuous)" /protein_id="NP_390081.1" /db_xref="EnsemblGenomes-Gn:BSU21980" /db_xref="EnsemblGenomes-Tr:CAB14116" /db_xref="GOA:P54163" /db_xref="InterPro:IPR003744" /db_xref="SubtiList:BG11607" /db_xref="UniProtKB/Swiss-Prot:P54163" /translation="MFNNSFWIFFAIIHFIIVLLFYKGFGKMGLFVWIGFATVCANLQ VVKTVELFGLTATLGNVMYGTIFFATDVLNEKYGPAEARKAVWLGFSTLLTLTFVMQG VLLFEPASSDISQTALETIFGFLPRVALGSLLAFIFSQTLDVYVYSAIRRIFPSDRLL WLRNGGSTAVSQLFDTFIFTAVAFLGIYPADVWLHIFISTYLIKFAVSLISLPYAYAA KKMIPNDERSS*" gene 2175328..2176017 /gene="queP" /locus_tag="BSU_21980" /old_locus_tag="BSU21980" promotor_-10 complement(2175378) /Source="Nicolas_upshift_promotors" /id="U1723" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.417582417582418" /psig="0.92007992007992" /xcortree=644 /SigmaFactorBS="gactgtcgcaaaaccgatccaaacaaacagtcccattttgcc aaatcCTTTATAAAATAAAAGAacAatgataaaatgaatgatcgcaaaaaagatccaa a" /listShort="S830, ypeP, ypeQ" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 complement(2175381..2175397) /Source="Nicolas_upshift_promotors" /id="U1723" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.417582417582418" /psig="0.92007992007992" /xcortree=644 /SigmaFactorBS="gactgtcgcaaaaccgatccaaacaaacagtcccattttgcc aaatcCTTTATAAAATAAAAGAacAatgataaaatgaatgatcgcaaaaaagatccaa a" /listShort="S830, ypeP, ypeQ" /GFF_Attribute="listLong" /label="promotor_-35" upshifts complement(2175384) /Source="Nicolas_upshifts" /id="U1723" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.417582417582418" /psig="0.92007992007992" /xcortree=644 /SigmaFactorBS="gactgtcgcaaaaccgatccaaacaaacagtcccattttgcc aaatcCTTTATAAAATAAAAGAacAatgataaaatgaatgatcgcaaaaaagatccaa a" /listShort="S830, ypeP, ypeQ" /GFF_Attribute="listLong" S_feature complement(2175385..2175774) /Source="Nicolas_S_feature" /locus_tag="new_2309787_2310176_c" /HighExp="S5, S4, S6, S7, S8, T5.0H, S3, T4.0H, BT, M9-stat" /AntisenseName="ypdP" /AntisenseCor="-0.645700204826543" /AntisenseRegPval="-32.4" /CDS_PredictionProba="NA" /TUshortSig="SigH" /TUshortPSig="0.564" /TUlongSig="NA" /TUlongPSig="NA" /label="S831" promotor_-10 complement(2175755..2175774) /Source="Nicolas_upshift_promotors" /id="U1724" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.564435564435564" /psig="0.564435564435564" /xcortree=1217 /SigmaFactorBS="ctgtactgccgccgtttctgagccataaaagccgatcaGAAG GAAATatccttctaatTGCCGAATATACATAAACATccagcgtttggctgaagataaa g" /listShort="S831, S830, ypeP, ypeQ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2175772) /Source="Nicolas_upshifts" /id="U1724" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.564435564435564" /psig="0.564435564435564" /xcortree=1217 /SigmaFactorBS="ctgtactgccgccgtttctgagccataaaagccgatcaGAAG GAAATatccttctaatTGCCGAATATACATAAACATccagcgtttggctgaagataaa g" /listShort="S831, S830, ypeP, ypeQ" /GFF_Attribute="listLong" promotor_-35 complement(2175786..2175794) /Source="Nicolas_upshift_promotors" /id="U1724" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.564435564435564" /psig="0.564435564435564" /xcortree=1217 /SigmaFactorBS="ctgtactgccgccgtttctgagccataaaagccgatcaGAAG GAAATatccttctaatTGCCGAATATACATAAACATccagcgtttggctgaagataaa g" /listShort="S831, S830, ypeP, ypeQ" /GFF_Attribute="listLong" /label="promotor_-35" CDS 2176017..2176415 /gene="ypdQ" /locus_tag="BSU_21990" /old_locus_tag="BSU21990" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 9888800, 10094689, 15115438, 17905985; Product type f: factor" /codon_start=1 /transl_table=11 /product="putative RNA binding protein (no RNase H activity)" /protein_id="NP_390082.1" /db_xref="EnsemblGenomes-Gn:BSU21990" /db_xref="EnsemblGenomes-Tr:CAB14117" /db_xref="GOA:P54162" /db_xref="InterPro:IPR002156" /db_xref="InterPro:IPR012337" /db_xref="InterPro:IPR036397" /db_xref="SubtiList:BG11608" /db_xref="UniProtKB/Swiss-Prot:P54162" /translation="MPTEIYVDGASAGNPGPSGIGIFIKHEGKAESFSIPIGVHTNQE AEFLALIEGMKLCATRGYQSVSFRTDSDIVERATELEMVKNITFQPFVEEIIRLKAAF PLFFIKWIPGKQNQKADLLAKEAIRLNEKN*" gene 2176017..2176415 /gene="ypdQ" /locus_tag="BSU_21990" /old_locus_tag="BSU21990" promotor_-35 2176408..2176414 /Source="Nicolas_upshift_promotors" /id="U1725" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=921 /SigmaFactorBS="gcaaaagaagcgattcggctgaatgaaaAGAATTAaatcttg atcattgGTTCATCCTAATggcgaggtgaactaacatgaaaaagaaagataaaggccg g" /listShort="sspL, S832" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2176429..2176440 /Source="Nicolas_upshift_promotors" /id="U1725" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=921 /SigmaFactorBS="gcaaaagaagcgattcggctgaatgaaaAGAATTAaatcttg atcattgGTTCATCCTAATggcgaggtgaactaacatgaaaaagaaagataaaggccg g" /listShort="sspL, S832" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2176440 /Source="Nicolas_upshifts" /id="U1725" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=921 /SigmaFactorBS="gcaaaagaagcgattcggctgaatgaaaAGAATTAaatcttg atcattgGTTCATCCTAATggcgaggtgaactaacatgaaaaagaaagataaaggccg g" /listShort="sspL, S832" /GFF_Attribute="listLong" CDS 2176457..2176585 /gene="sspL" /locus_tag="BSU_22000" /old_locus_tag="BSU22000" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:10333516" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10333516; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="small acid-soluble spore protein" /protein_id="YP_054584.1" /db_xref="EnsemblGenomes-Gn:BSU22000" /db_xref="EnsemblGenomes-Tr:CAE01458" /db_xref="GOA:Q7WY66" /db_xref="InterPro:IPR017526" /db_xref="SubtiList:BG14176" /db_xref="UniProtKB/Swiss-Prot:Q7WY66" /translation="MKKKDKGRLTGGVTPQGDLEGNTHNDPKTELEERAKKSNTKR*" gene 2176457..2176585 /gene="sspL" /locus_tag="BSU_22000" /old_locus_tag="BSU22000" S_feature 2176586..2177566 /Source="Nicolas_S_feature" /locus_tag="new_2310988_2311968" /HighExp="S8, S7, S5, S6, S4, C30, nit, ferm, Pyr, S3" /AntisenseName="exoA" /AntisenseCor="-0.365099613028674" /AntisenseRegPval="-9.1999999999999993" /CDS_PredictionProba="NA" /TUshortSig="SigGF, SigA" /TUshortPSig="0.999, 0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S832" CDS complement(2176593..2177483) /gene="exnP" /locus_tag="BSU_22010" /old_locus_tag="BSU22010" /function="16.6: Maintain" /function="16.9: Replicate" /experiment="publication(s) with functional evidences, PMID:16045613, 17038322, 17905985, 27435445" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16045613, 17038322, 17905985, 27435445; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="5'3'-exonuclease" /protein_id="NP_390083.1" /db_xref="EnsemblGenomes-Gn:BSU22010" /db_xref="EnsemblGenomes-Tr:CAB14118" /db_xref="GOA:P54161" /db_xref="InterPro:IPR002421" /db_xref="InterPro:IPR008918" /db_xref="InterPro:IPR020045" /db_xref="InterPro:IPR020046" /db_xref="InterPro:IPR029060" /db_xref="InterPro:IPR036279" /db_xref="SubtiList:BG11606" /db_xref="UniProtKB/Swiss-Prot:P54161" /translation="MNNNKLLLVDGMALLFRAFFATAVHRNFMINDSGVPTNGVNGFL KHLITAVETFQPTHVVCCWDMGSKTYRNDLFQDYKANRSAPPVELIPQFDLAKEAAAE LGIMNIGFAGYEADDCIGTLADLFANEADITVVTGDRDLLQLLTDKVSVALLQKGIGN YKVYTKETFYEETGVMPKALIDIKALMGDSSDNYPGVKGIGEKTAYKLIREYETIDRL LENLSLLPKGQQGKIQQGLSDLEMSRKLAEIHCSVPLACTLKDALFTLQMEQAADMLR RHQIKGIERMLEKLNAREIV*" gene complement(2176593..2177483) /gene="exnP" /locus_tag="BSU_22010" /old_locus_tag="BSU22010" downshifts complement(2176630) /Source="Nicolas_upshifts" /id="D1152" /incds=0 /nref=10 /ntot=174 /MaxReadThrough="2.94148" /MaxDrop="4.49836" /score="3.60870815" /energy="-15.6" /TU="U1726" /idTUdmin="U1726" /TUdmin="-284" /isTUend="FALSE" promotor_-10 complement(2177505..2177524) /Source="Nicolas_upshift_promotors" /id="U1726" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.999000999001" /psig=1 /xcortree=2164 /SigmaFactorBS="acagtatctctaattaaagagatactgtttTTTATTTttggg ctgcttTATGATAAAATAGAAGGAATgaaagaaaagggagttatttgatgaataataa t" /listShort="exoA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2177512) /Source="Nicolas_upshifts" /id="U1726" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.999000999001" /psig=1 /xcortree=2164 /SigmaFactorBS="acagtatctctaattaaagagatactgtttTTTATTTttggg ctgcttTATGATAAAATAGAAGGAATgaaagaaaagggagttatttgatgaataataa t" /listShort="exoA" /GFF_Attribute="listLong" promotor_-35 complement(2177536..2177542) /Source="Nicolas_upshift_promotors" /id="U1726" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.999000999001" /psig=1 /xcortree=2164 /SigmaFactorBS="acagtatctctaattaaagagatactgtttTTTATTTttggg ctgcttTATGATAAAATAGAAGGAATgaaagaaaagggagttatttgatgaataataa t" /listShort="exoA" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 2177540 /Source="Nicolas_upshifts" /id="D1153" /incds=0 /nref=4 /ntot=32 /MaxReadThrough="0.83304" /MaxDrop="4.41573" /score="0.126370352" /energy="-15" /TU="NA" /idTUdmin="U1725" /TUdmin=16 /isTUend="TRUE" CDS complement(2177584..2177730) /gene="ypzF" /locus_tag="BSU_22019" /old_locus_tag="BSU22019" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_003097753.1" /db_xref="EnsemblGenomes-Gn:BSU22019" /db_xref="EnsemblGenomes-Tr:CAX52652" /db_xref="UniProtKB/Swiss-Prot:C0H443" /translation="MLGRTKLGNRNAQANNNAKKKNGFQTHFDSYAGREAEKLIASNK RHND*" gene complement(2177584..2177730) /gene="ypzF" /locus_tag="BSU_22019" /old_locus_tag="BSU22019" downshifts complement(2177600) /Source="Nicolas_upshifts" /id="D1154" /incds=0 /nref=253 /ntot=272 /MaxReadThrough="0.89691" /MaxDrop="8.47168" /score="25.632979" /energy="-12" /TU="NA" /idTUdmin="U1727" /TUdmin=0 /isTUend="TRUE" upshifts complement(2177754) /Source="Nicolas_upshifts" /id="U1727" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=846 /SigmaFactorBS="ccgcatgtaagctggatgatcctgtcgCGAGTGAacctcctg ccggaaGCATATACTATAtgcatccgacgtaaggggggattcatgttgggcagaacaa a" /listShort="ypzF" /GFF_Attribute="listLong" promotor_-10 complement(2177755..2177766) /Source="Nicolas_upshift_promotors" /id="U1727" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=846 /SigmaFactorBS="ccgcatgtaagctggatgatcctgtcgCGAGTGAacctcctg ccggaaGCATATACTATAtgcatccgacgtaaggggggattcatgttgggcagaacaa a" /listShort="ypzF" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 complement(2177781..2177787) /Source="Nicolas_upshift_promotors" /id="U1727" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=846 /SigmaFactorBS="ccgcatgtaagctggatgatcctgtcgCGAGTGAacctcctg ccggaaGCATATACTATAtgcatccgacgtaaggggggattcatgttgggcagaacaa a" /listShort="ypzF" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2177805..2178062) /gene="ypbS" /locus_tag="BSU_22020" /old_locus_tag="BSU22020" /experiment="publication(s) with functional evidences, PMID:20709900, 22720735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 20709900, 22720735; Product type f: factor" /codon_start=1 /transl_table=11 /product="spore associated protein" /protein_id="NP_390084.1" /db_xref="EnsemblGenomes-Gn:BSU22020" /db_xref="EnsemblGenomes-Tr:CAB14119" /db_xref="InterPro:IPR019688" /db_xref="SubtiList:BG11605" /db_xref="UniProtKB/Swiss-Prot:P54160" /translation="MSEVHKAISAHSSKQHEHIKAFMRLENMRELAIEEAVAKCRNDE PYTTDAINEITEQMNQLAKKGIVPTRRLVSKEMVREYVSRM*" gene complement(2177805..2178062) /gene="ypbS" /locus_tag="BSU_22020" /old_locus_tag="BSU22020" promotor_-10 complement(2178082..2178101) /Source="Nicolas_upshift_promotors" /id="U1728" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.678321678321678" /psig=1 /xcortree=3060 /SigmaFactorBS="gaaaaattcagacaatacaataaaaatgtaaaattcaGTTGG CTTgtatttcaagtCATGATAGACTAAATAGAAAaaagcgagatgaacgattaatgtc a" /listShort="ypbS, ypzF" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2178097) /Source="Nicolas_upshifts" /id="U1728" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.678321678321678" /psig=1 /xcortree=3060 /SigmaFactorBS="gaaaaattcagacaatacaataaaaatgtaaaattcaGTTGG CTTgtatttcaagtCATGATAGACTAAATAGAAAaaagcgagatgaacgattaatgtc a" /listShort="ypbS, ypzF" /GFF_Attribute="listLong" promotor_-35 complement(2178113..2178120) /Source="Nicolas_upshift_promotors" /id="U1728" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.678321678321678" /psig=1 /xcortree=3060 /SigmaFactorBS="gaaaaattcagacaatacaataaaaatgtaaaattcaGTTGG CTTgtatttcaagtCATGATAGACTAAATAGAAAaaagcgagatgaacgattaatgtc a" /listShort="ypbS, ypzF" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2178127..2181708) /gene="dynA" /locus_tag="BSU_22030" /old_locus_tag="BSU22030" /EC_number="3.6.5.5" /experiment="publication(s) with functional evidences, PMID:21205012, 23388828, 23249255, 26842743, 26530236" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 21205012, 23388828, 23249255, 26842743, 26530236; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="dynamin GTPase" /protein_id="NP_390085.1" /db_xref="EnsemblGenomes-Gn:BSU22030" /db_xref="EnsemblGenomes-Tr:CAB14120" /db_xref="GOA:P54159" /db_xref="InterPro:IPR022812" /db_xref="InterPro:IPR027094" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG11604" /db_xref="UniProtKB/Swiss-Prot:P54159" /translation="MTDQNRKELLHKTGELYKQFIENQDEQRAAKLAAVMKKAADEEV YIAFTGHYSAGKSSLLNCLLMENILPTSPIPTSANLVVIRNGEKRVRLHTTDGACAEL EGTYQKDKVQQYCKDGEQIESVEIFDRYTEIDSGVAYIDTPGIDSTDDAHFLSAASIL HQADALFYVVHYNHVHAEENVKFLRSIKESIPNVYFIVNQIDRHDETETKFGDYQAQV EEMLCNEGISREALYFTSVTEPDHPFNQMGALREELSRIEQQSKSNMQALTEQKVRNL LKEHTEMLKKDETGAPSFAEQLNIHTGLVQSLRDQLDEAEKQMTEAEKRMQEEINRIL KNANLTPFEMRELAAAFLESQEPSFKTGFFFSKAKTAQERDKRRNAFFSDVAKRTEAE ADWHMIDTLHKLAKVFDVYTAESEKLIQAYRTPLDISIIEHAVKHGAAFSSEYVLQYT KDLAELIRKEAKREAADIIKVLSAMVKERVSKDVQTINDRLVQESEKLVFLQEQARLE NNAREKTDRLWAIWEEESACPMHIDTEWFKSKKTRVAAPEQKQGRSQLTAQPMPKSEI KMEQEMPLQDQIKRFYTLSDILGECSMLLKQTSAFRERVKRLEERKFTLALFGGFSSG KSSFANALVGERVLPSSPTPTTATINKITKPINGNLNKTANVVFKTEDDLTAEILQLT GIPKEPAGRSFTEKWEKAVKKNRLQEEHVKLISNFLLAYEKYQQYIQEQKKLTIPLSE LKPYVAEETTACAVKEVTVYYTCPLTEKGITIVDTPGASSMNKRHTELAFQYIKDADA FFYMTYYQHSFSKGDRSFLRKLGLVKESLSMDKMFFIINAADLAKDKTELETVTDYVS AELVKEGVYEPQLFTVSSKEELVGKPESFYNQFSKVRKHLDRFIEVDVKKASAAQLSS EADKLCETVFQLHQSQHQSREEKEAQKQCLMLSFERTAADIEKRRNSKTIIEKVKKDT REQLYHIAQRLSYFANDLLKSAFHPGLQNGDWKKNVSKAMTTALHEYLFEYIQEIKTL DVRMSGFIERHINEEWLDHFQKTLNEDGYFSVYAGDQHSNGIQLKEVEPEIEERAFEQ ELKEIKSPKQFFEQKGKATFIEAVRMKLTKITEAWIKNEEESLISHYTAHLRRLQEDM GEKAIAQITDQKETYLRGYAEGEHAKEIEMAYQACISWKNSDNTIKM*" gene complement(2178127..2181708) /gene="dynA" /locus_tag="BSU_22030" /old_locus_tag="BSU22030" S_feature complement(2181709..2181780) /Source="Nicolas_S_feature" /locus_tag="new_2316111_2316182_c" /HighExp="LBGstat, T1.30H, T1.0H, BMM, T2.30H, M9-stat, MG 150, T0.30H, T2.0H, GM-0.2" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.987" /TUlongSig="NA" /TUlongPSig="NA" /label="S833" misc_feature complement(2181770..2181789) /Source="Nicolas_upshift_promotors" /id="U1729" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.61038961038961" /psig="0.987012987012987" /xcortree=2239 /SigmaFactorBS="gctgccgtaatggcggcttttttctattctcctaaagaaatt tggtttattCTTGTGTAAAATGAAAAGGGaatgaattcagatctttcgaaaaaggttc a" /listShort="S833, ypbR" /listLong="ypbS, ypzF" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(2181780) /Source="Nicolas_upshifts" /id="U1729" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.61038961038961" /psig="0.987012987012987" /xcortree=2239 /SigmaFactorBS="gctgccgtaatggcggcttttttctattctcctaaagaaatt tggtttattCTTGTGTAAAATGAAAAGGGaatgaattcagatctttcgaaaaaggttc a" /listShort="S833, ypbR" /listLong="ypbS, ypzF" S_feature complement(2181825..2182022) /Source="Nicolas_S_feature" /locus_tag="new_2316227_2316424_c" /HighExp="HiOs, B60, GM 25, S7, GM 15, B36, S5, S8, GM 5, GM 60" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.24118200000000001" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S834" downshifts complement(2181868) /Source="Nicolas_upshifts" /id="D1155" /incds=0 /nref=1 /ntot=38 /MaxReadThrough="3.11615" /MaxDrop="3.46525" /score="27.1937922" /energy="-9.7" /TU="U1730" /idTUdmin="U1730" /TUdmin="-22" /isTUend="TRUE" CDS complement(2181884..2181973) /gene="fbpC" /locus_tag="BSU_22036" /old_locus_tag="BSU22036" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:18697947, 22389480, 22427629" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 18697947, 22389480, 22427629; Product type r: regulator" /codon_start=1 /transl_table=11 /product="regulator of iron homeostasis" /protein_id="YP_009513974.1" /db_xref="EnsemblGenomes-Gn:BSU22036" /db_xref="EnsemblGenomes-Tr:CCQ48599" /db_xref="UniProtKB/TrEMBL:L8ECR0" /translation="MTMLFLLGAVCTYSVLIGFVLKGISNKSV*" gene complement(2181884..2181973) /gene="fbpC" /locus_tag="BSU_22036" /old_locus_tag="BSU22036" promotor_-10 complement(2182001..2182020) /Source="Nicolas_upshift_promotors" /id="U1730" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.867132867132867" /psig=1 /xcortree=2098 /SigmaFactorBS="gcagaagacaaagcattacaggaatacagcgtaaaatagcGA TTGAAAatcattctcaaccaTGTTAAAATGGGTTTGAAAAagattctcaatcaggatg g" /listShort="S834" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2182022) /Source="Nicolas_upshifts" /id="U1730" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.867132867132867" /psig=1 /xcortree=2098 /SigmaFactorBS="gcagaagacaaagcattacaggaatacagcgtaaaatagcGA TTGAAAatcattctcaaccaTGTTAAAATGGGTTTGAAAAagattctcaatcaggatg g" /listShort="S834" /GFF_Attribute="listLong" promotor_-35 complement(2182035..2182042) /Source="Nicolas_upshift_promotors" /id="U1730" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.867132867132867" /psig=1 /xcortree=2098 /SigmaFactorBS="gcagaagacaaagcattacaggaatacagcgtaaaatagcGA TTGAAAatcattctcaaccaTGTTAAAATGGGTTTGAAAAagattctcaatcaggatg g" /listShort="S834" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2182044..2182550) /gene="bpsB" /locus_tag="BSU_22040" /old_locus_tag="BSU22040" /EC_number="2.1.1.-" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:12354229, 15849754, 16850406, 7726551, 8396117, 19465653" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12354229, 15849754, 16850406, 7726551, 8396117, 19465653; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="alkylpyrone methyltransferase (polyketide synthesis)" /protein_id="NP_390086.1" /db_xref="EnsemblGenomes-Gn:BSU22040" /db_xref="EnsemblGenomes-Tr:CAB14121" /db_xref="GOA:P54158" /db_xref="InterPro:IPR007269" /db_xref="SubtiList:BG11603" /db_xref="UniProtKB/Swiss-Prot:P54158" /translation="MFWLLIAILIVQRAAEMAVARQNEQKVKKQGAIEFGESHYPYII TMHILFFLSLIAEVLLMNKQPSSWWLGIAAVILSVQIVRYWALCSLGAYWNTKILVVP GVELVKKGPYKWMKHPNYAVVILEILLIPLLYQAYVTMCLFSIFNAVLLSVRIRAEDK ALQEYSVK*" gene complement(2182044..2182550) /gene="bpsB" /locus_tag="BSU_22040" /old_locus_tag="BSU22040" CDS complement(2182554..2183651) /gene="bpsA" /locus_tag="BSU_22050" /old_locus_tag="BSU22050" /EC_number="2.3.1.-" /function="15.10: Adaptations to atypical conditions" /experiment="publication(s) with functional evidences, PMID:19465653" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 19465653; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="promiscuous alkylpyrone synthase BpsA (polyketide synthesis)" /protein_id="NP_390087.1" /db_xref="EnsemblGenomes-Gn:BSU22050" /db_xref="EnsemblGenomes-Tr:CAB14122" /db_xref="GOA:P54157" /db_xref="InterPro:IPR001099" /db_xref="InterPro:IPR011141" /db_xref="InterPro:IPR012328" /db_xref="InterPro:IPR016039" /db_xref="InterPro:IPR018088" /db_xref="SubtiList:BG11523" /db_xref="UniProtKB/Swiss-Prot:P54157" /translation="MAFILSIGTSLPAYNVNQEKAAEFARYMFQHSFKDIDRLLSSFK NGQIHSRQFVKPIEWYKEGHSFEEKNQIYIEETLKHSRAAVRECLSHPEFFQEAIPYE KVEAVFFVSSTGLSTPSIEARLMNELPFSPYTKRIPIWGLGCAGGASGLARAAEYCKA YPEAFVLVISAELCSLTFQPEDKTKSNLIGTSLFGDGIAAALLCGEKADRRVSKLKLA PKIMDAQSVLMKQSEDVMGWDFTDQGFKVIFSRDIPTLVEKWLKTNVQIFLDKHKLSF HDISVFLAHPGGKKVIDAYIKSLGLSSEKLSSAQSILQKHGNMSSATILYVIKDHLQN GHKKEAERGLIGALGPGFSSELLLFSWEKGA*" gene complement(2182554..2183651) /gene="bpsA" /locus_tag="BSU_22050" /old_locus_tag="BSU22050" promotor_-10 complement(2183669..2183680) /Source="Nicolas_upshift_promotors" /id="U1731" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.995004995004995" /psig="0.995004995004995" /xcortree=901 /SigmaFactorBS="cagtctaactccgccgcggcggagtttttttTGCATATaaaa aagattgttgCGGCACAATGTAtgcaaagaggtgatcgcatggcgtttattttatcca t" /listShort="bcsA, ypbQ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2183672) /Source="Nicolas_upshifts" /id="U1731" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.995004995004995" /psig="0.995004995004995" /xcortree=901 /SigmaFactorBS="cagtctaactccgccgcggcggagtttttttTGCATATaaaa aagattgttgCGGCACAATGTAtgcaaagaggtgatcgcatggcgtttattttatcca t" /listShort="bcsA, ypbQ" /GFF_Attribute="listLong" promotor_-35 complement(2183695..2183701) /Source="Nicolas_upshift_promotors" /id="U1731" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.995004995004995" /psig="0.995004995004995" /xcortree=901 /SigmaFactorBS="cagtctaactccgccgcggcggagtttttttTGCATATaaaa aagattgttgCGGCACAATGTAtgcaaagaggtgatcgcatggcgtttattttatcca t" /listShort="bcsA, ypbQ" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2183725..2185041) /gene="pbuX" /locus_tag="BSU_22060" /old_locus_tag="BSU22060" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:9098051, 12923093, 15549109, 15849754, 16850406" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9098051, 12923093, 15549109, 15849754, 16850406; Product type t : transporter" /codon_start=1 /transl_table=11 /product="xanthine permease" /protein_id="NP_390088.1" /db_xref="EnsemblGenomes-Gn:BSU22060" /db_xref="EnsemblGenomes-Tr:CAB14123" /db_xref="GOA:P42086" /db_xref="InterPro:IPR006042" /db_xref="InterPro:IPR006043" /db_xref="InterPro:IPR017588" /db_xref="SubtiList:BG11080" /db_xref="UniProtKB/Swiss-Prot:P42086" /translation="MRNGFGKTLSLGIQHVLAMYAGAIVVPLIVGKAMGLTVEQLTYL VSIDIFMCGVATLLQVWSNRFFGIGLPVVLGCTFTAVSPMIAIGSEYGVSTVYGSIIA SGILVILISFFFGKLVSFFPPVVTGSVVTIIGITLMPVAMNNMAGGEGSADFGDLSNL ALAFTVLSIIVLLYRFTKGFIKSVSILIGILIGTFIAYFMGKVQFDNVSDAAVVQMIQ PFYFGAPSFHAAPIITMSIVAIVSLVESTGVYFALGDLTNRRLTEIDLSKGYRAEGLA VLLGGIFNAFPYTAFSQNVGLVQLTGIKKNAVIVVTGVILMAFGLFPKIAAFTTIIPS AVLGGAMVAMFGMVIAYGIKMLSRIDFAKQENLLIVACSVGLGLGVTVVPDIFKQLPS ALTLLTTNGIVAGSFTAVVLNIVYNVFSKAKKIEQEADLAEQKTAV*" gene complement(2183725..2185041) /gene="pbuX" /locus_tag="BSU_22060" /old_locus_tag="BSU22060" downshifts complement(2183738) /Source="Nicolas_upshifts" /id="D1156" /incds=0 /nref=177 /ntot=215 /MaxReadThrough="1.81377" /MaxDrop="6.3089" /score="32.8866099" /energy="-9" /TU="U1733" /idTUdmin="U1732" /TUdmin=0 /isTUend="TRUE" CDS complement(2185038..2185622) /gene="xpt" /locus_tag="BSU_22070" /old_locus_tag="BSU22070" /EC_number="2.4.2.22" /function="16.11: Scavenge (Catabolism)" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:12923093, 15549109, 19381559, 20108980, 20200045" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12923093, 15549109, 19381559, 20108980, 20200045; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="xanthine phosphoribosyltransferase" /protein_id="NP_390089.1" /db_xref="EnsemblGenomes-Gn:BSU22070" /db_xref="EnsemblGenomes-Tr:CAB14124" /db_xref="GOA:P42085" /db_xref="InterPro:IPR000836" /db_xref="InterPro:IPR010079" /db_xref="InterPro:IPR029057" /db_xref="PDB:1Y0B" /db_xref="PDB:2FXV" /db_xref="SubtiList:BG11079" /db_xref="UniProtKB/Swiss-Prot:P42085" /translation="MEALKRKIEEEGVVLSDQVLKVDSFLNHQIDPLLMQRIGDEFAS RFAKDGITKIVTIESSGIAPAVMTGLKLGVPVVFARKHKSLTLTDNLLTASVYSFTKQ TESQIAVSGTHLSDQDHVLIIDDFLANGQAAHGLVSIVKQAGASIAGIGIVIEKSFQP GRDELVKLGYRVESLARIQSLEEGKVSFVQEVHS*" gene complement(2185038..2185622) /gene="xpt" /locus_tag="BSU_22070" /old_locus_tag="BSU22070" misc_RNA complement(2185711..2185811) /gene="gswA" /locus_tag="BSU_misc_RNA_34" /product="guanine riboswitch" /experiment="publication(s) with functional evidences, PMID:12787499, 15549109, 18072940, 19603494, 20022916, 20200045, 20204714, 21439477" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12787499, 15549109, 18072940, 19603494, 20022916, 20200045, 20204714, 21439477; Product type n: RNA" gene complement(2185711..2185811) /gene="gswA" /locus_tag="BSU_misc_RNA_34" downshifts complement(2185718) /Source="Nicolas_upshifts" /id="D1157" /incds=0 /nref=8 /ntot=35 /MaxReadThrough="6.97435" /MaxDrop="3.25" /score="36.5247418" /energy="-19.2" /TU="U1732,U1733" /idTUdmin="U1734" /TUdmin=1870 /isTUend="FALSE" S_feature complement(2185812..2185952) /Source="Nicolas_S_feature" /locus_tag="new_2320214_2320354_c" /HighExp="dia15, BT, dia5, Diami, C90, LBGtran, Lbtran, Gly, SMMPr, M0t45" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="Sig-, SigA" /TUshortPSig="0.291, 0.992" /TUlongSig="NA" /TUlongPSig="NA" /label="S835" CDS complement(2185953..2187458) /gene="ypwA" /locus_tag="BSU_22080" /old_locus_tag="BSU22080" /EC_number="3.4.17.19" /function="16.11: Scavenge (Catabolism)" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 7765282, 22730127; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="metal-dependent carboxypeptidase" /protein_id="NP_390090.1" /db_xref="EnsemblGenomes-Gn:BSU22080" /db_xref="EnsemblGenomes-Tr:CAB14125" /db_xref="GOA:P50848" /db_xref="InterPro:IPR001333" /db_xref="PDB:3HQ2" /db_xref="SubtiList:BG11458" /db_xref="UniProtKB/Swiss-Prot:P50848" /translation="MEIHTYEKEFFDLLKRISHYSEAVALMHWDSRTGAPKNGSEDRA ESIGQLSTDIFNIQTSDRMKELIDVLYERFDDLSEDTKKAVELAKKEYEENKKIPEAE YKEYVILCSKAETAWEEAKGKSDFSLFSPYLEQLIEFNKRFITYWGYQEHPYDALLDL FEPGVTVKVLDQLFAELKEAIIPLVKQVTASGNKPDTSFITKAFPKEKQKELSLYFLQ ELGYDFDGGRLDETVHPFATTLNRGDVRVTTRYDEKDFRTAIFGTIHECGHAIYEQNI DEALSGTNLSDGASMGIHESQSLFYENFIGRNKHFWTPYYKKIQEASPVQFKDISLDD FVRAINESKPSFIRVEADELTYPLHIIIRYEIEKAIFSNEVSVEDLPSLWNQKYQDYL GITPQTDAEGILQDVHWAGGDFGYFPSYALGYMYAAQLKQKMLEDLPEFDALLERGEF HPIKQWLTEKVHIHGKRKKPLDIIKDATGEELNVRYLIDYLSNKYSNLYLL*" gene complement(2185953..2187458) /gene="ypwA" /locus_tag="BSU_22080" /old_locus_tag="BSU22080" promotor_no_box complement(2187394..2187494) /Source="Nicolas_upshift_promotors" /id="U1732" /multdbtbs="-" /comp="M21" /sig="Sig-" /pcomp="0.382617382617383" /psig="0.290709290709291" /xcortree=1802 /SigmaFactorBS="ctgtaatggaacggctagaatagggagggaatggatatggag atacatacatatgaaaaagaattttttgatcttttaaaaagaatctcacattacagcg a" /listShort="ypwA, S835, NA, xpt, pbuX" /GFF_Attribute="listLong" /label="promotor_no_box" upshifts complement(2187434) /Source="Nicolas_upshifts" /id="U1732" /multdbtbs="-" /comp="M21" /sig="Sig-" /pcomp="0.382617382617383" /psig="0.290709290709291" /xcortree=1802 /SigmaFactorBS="ctgtaatggaacggctagaatagggagggaatggatatggag atacatacatatgaaaaagaattttttgatcttttaaaaagaatctcacattacagcg a" /listShort="ypwA, S835, NA, xpt, pbuX" /GFF_Attribute="listLong" downshifts 2187446 /Source="Nicolas_upshifts" /id="D1158" /incds=0 /nref=4 /ntot=78 /MaxReadThrough="1.34397" /MaxDrop="3.87399" /score="12.6922524" /energy="-13.3" /TU="NA" /idTUdmin="U1735" /TUdmin="-5588" /isTUend="FALSE" promotor_-10 complement(2187484..2187503) /Source="Nicolas_upshift_promotors" /id="U1733" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.905094905094905" /psig="0.992007992007992" /xcortree=2219 /SigmaFactorBS="ctgccacaaaacataccggcagccttttatacaaacAATTTG ACtttcataccccctTCCATTAGCCTGTAATGGAAcggctagaatagggagggaatgg a" /listShort="ypwA, S835, NA, xpt, pbuX" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2187500) /Source="Nicolas_upshifts" /id="U1733" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.905094905094905" /psig="0.992007992007992" /xcortree=2219 /SigmaFactorBS="ctgccacaaaacataccggcagccttttatacaaacAATTTG ACtttcataccccctTCCATTAGCCTGTAATGGAAcggctagaatagggagggaatgg a" /listShort="ypwA, S835, NA, xpt, pbuX" /GFF_Attribute="listLong" promotor_-35 complement(2187517..2187524) /Source="Nicolas_upshift_promotors" /id="U1733" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.905094905094905" /psig="0.992007992007992" /xcortree=2219 /SigmaFactorBS="ctgccacaaaacataccggcagccttttatacaaacAATTTG ACtttcataccccctTCCATTAGCCTGTAATGGAAcggctagaatagggagggaatgg a" /listShort="ypwA, S835, NA, xpt, pbuX" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2187570..2188562) /gene="kdgT" /locus_tag="BSU_22090" /old_locus_tag="BSU22090" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2b: Function from indirect experimental evidences (e.g. phenotypes); PubMedId: 15849754, 16850406, 9846747; Product type t: transporter" /codon_start=1 /transl_table=11 /product="2-keto-3-deoxygluconate permease" /protein_id="NP_390091.1" /db_xref="EnsemblGenomes-Gn:BSU22090" /db_xref="EnsemblGenomes-Tr:CAB14126" /db_xref="GOA:P50847" /db_xref="InterPro:IPR004684" /db_xref="InterPro:IPR018395" /db_xref="SubtiList:BG11399" /db_xref="UniProtKB/Swiss-Prot:P50847" /translation="MKIKATIERVPGGMMIIPLFLGAALNTFAPGTAEFFGGFTGALI TGTLPILGVFIFCVGATIDFRSSGYIARKGITLLLGKIGFAALLGVIAAQFIPDDGIQ SGFFAGLSVLAIVAVMNETNGGLYLALMNHMGRKEDAGAFAFISTESGPFMTMVTFGV TGLAAFPWETLAATVIPFLLGCILGNLDHDLRDLFSKVVPAIIPFFAFSLGNTLNFGM LIQSGLLGIFIGVSVVILSGSSLFLLDRFIARGDGVAGVAASSTAGAAVAVPYALAEA NASFAPVAESATAIIATSVIVTSLLTPLATVWVDKKIKQKKRRTPPPKNQMTIN*" gene complement(2187570..2188562) /gene="kdgT" /locus_tag="BSU_22090" /old_locus_tag="BSU22090" downshifts complement(2187588) /Source="Nicolas_upshifts" /id="D1159" /incds=0 /nref=15 /ntot=59 /MaxReadThrough="3.32882" /MaxDrop="5.85236" /score="36.5247418" /energy="-19.2" /TU="NA" /idTUdmin="U1734" /TUdmin=0 /isTUend="TRUE" CDS complement(2188607..2189197) /gene="kdgA" /locus_tag="BSU_22100" /old_locus_tag="BSU22100" /EC_number="4.1.2.14" /function="16.2: Construct biomass (Anabolism)" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 9846747, 10368143; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="2-keto-3-deoxygluconate-6-phosphate aldolase" /protein_id="NP_390092.1" /db_xref="EnsemblGenomes-Gn:BSU22100" /db_xref="EnsemblGenomes-Tr:CAB14127" /db_xref="GOA:P50846" /db_xref="InterPro:IPR000887" /db_xref="InterPro:IPR013785" /db_xref="InterPro:IPR031338" /db_xref="SubtiList:BG11396" /db_xref="UniProtKB/Swiss-Prot:P50846" /translation="MESKVVENRLKEAKLIAVIRSKDKQEACQQIESLLDKGIRAVEV TYTTPGASDIIESFRNREDILIGAGTVISAQQAGEAAKAGAQFIVSPGFSADLAEHLS FVKTHYIPGVLTPSEIMEALTFGFTTLKLFPSGVFGIPFMKNLAGPFPQVTFIPTGGI HPSEVPDWLRAGAGAVGVGSQLGSCSKEDLQAVFQV*" gene complement(2188607..2189197) /gene="kdgA" /locus_tag="BSU_22100" /old_locus_tag="BSU22100" CDS complement(2189199..2190173) /gene="kdgK" /locus_tag="BSU_22110" /old_locus_tag="BSU22110" /EC_number="2.7.1.45" /function="16.11: Scavenge (Catabolism)" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 9846747, 10368143, 15039578; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="2-keto-3-deoxygluconate kinase" /protein_id="NP_390093.1" /db_xref="EnsemblGenomes-Gn:BSU22110" /db_xref="EnsemblGenomes-Tr:CAB14128" /db_xref="GOA:P50845" /db_xref="InterPro:IPR002173" /db_xref="InterPro:IPR011611" /db_xref="InterPro:IPR029056" /db_xref="SubtiList:BG11397" /db_xref="UniProtKB/Swiss-Prot:P50845" /translation="MKLDAVTFGESMAMFYANEYGGLHEVSTFSKGLAGAESNVACGL ARLGFRMGWMSKVGNDQLGTFILQELKKEGVDVSRVIRSQDENPTGLLLKSKVKEGDP QVTYYRKNSAASTLTTAEYPRDYFQCAGHLHVTGIPPALSAEMKDFTYHVMNDMRNAG KTISFDPNVRPSLWPDQATMVHTINDLAGLADWFFPGIAEGELLTGEKTPEGIADYYL KKGASFVAIKLGKEGAYFKTGTSEGFLEGCRVDRVVDTVGAGDGFAVGVISGILDGLS YKDAVQRGNAIGALQVQAPGDMDGLPTREKLASFLSAQRTVHQKKGDY*" gene complement(2189199..2190173) /gene="kdgK" /locus_tag="BSU_22110" /old_locus_tag="BSU22110" CDS complement(2190211..2191230) /gene="kdgR" /locus_tag="BSU_22120" /old_locus_tag="BSU22120" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:9846747, 15223311, 17322190, 28040177" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9846747, 15223311, 17322190, 28040177; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional repressor of the Kdg operon (KdgR-galacturonate)" /protein_id="NP_390094.1" /db_xref="EnsemblGenomes-Gn:BSU22120" /db_xref="EnsemblGenomes-Tr:CAB14129" /db_xref="GOA:P50844" /db_xref="InterPro:IPR000843" /db_xref="InterPro:IPR010982" /db_xref="InterPro:IPR012310" /db_xref="InterPro:IPR028082" /db_xref="SubtiList:BG11398" /db_xref="UniProtKB/Swiss-Prot:P50844" /translation="MKKKTTGHTTIKDVAECAGVSKSTVSRYINGKIDAISPEKVKNI KKAIAELNYRPSKMAQGLKIKKSKLIGFVVADITNPFSVAAFRGVEEVCDQYGYSIMV CNTDNSPEKEREMLLKLEAHSVEGLILNATGENKDVLRAFAEQQIPTILIDRKLPDLK LDTVTTDNRWITKEILQKVYSKGYTDVALFTEPISSISPRAERAAVYQEMASVQNVNG LVRLHEIDVKDKEQLKAELRSFHKEMPEQKKAILALNGLIMLKIISCMEELGLRIPQD IGIAGFDDTEWYKLIGPGITTIAQPSHDMGRTAMERVLKRIEGDKGAPQTIELEAKVI MRKSL*" gene complement(2190211..2191230) /gene="kdgR" /locus_tag="BSU_22120" /old_locus_tag="BSU22120" promotor_-10 complement(2191278..2191297) /Source="Nicolas_upshift_promotors" /id="U1734" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.827172827172827" /psig=1 /xcortree=3226 /SigmaFactorBS="aaaataatgaattgacatattattaaaaaaacTCTTCCCAaa ttttaaaatTATGGTATTCTTTTGTTGTAacggttttgaaatcggtttcaaatatatg a" /listShort="kdgR, kdgK, kdgA, kdgT" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2191288) /Source="Nicolas_upshifts" /id="U1734" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.827172827172827" /psig=1 /xcortree=3226 /SigmaFactorBS="aaaataatgaattgacatattattaaaaaaacTCTTCCCAaa ttttaaaatTATGGTATTCTTTTGTTGTAacggttttgaaatcggtttcaaatatatg a" /listShort="kdgR, kdgK, kdgA, kdgT" /GFF_Attribute="listLong" promotor_-35 complement(2191309..2191316) /Source="Nicolas_upshift_promotors" /id="U1734" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.827172827172827" /psig=1 /xcortree=3226 /SigmaFactorBS="aaaataatgaattgacatattattaaaaaaacTCTTCCCAaa ttttaaaatTATGGTATTCTTTTGTTGTAacggttttgaaatcggtttcaaatatatg a" /listShort="kdgR, kdgK, kdgA, kdgT" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 2191351..2191358 /Source="Nicolas_upshift_promotors" /id="U1735" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.93906093906094" /psig=1 /xcortree=3227 /SigmaFactorBS="gaagagtttttttaataatatgtcaattcattattttttCGT TGACTcttttcactatttaTCCTAAAATTTTCTTTGAAAccgttaccaaaatattttc a" /listShort="S836, kduI, kduD" /GFF_Attribute="listLong" /label="promotor_-35" S_feature 2191372..2191451 /Source="Nicolas_S_feature" /locus_tag="new_2325774_2325853" /HighExp="HiTm, Heat, nit, LBGstat, ferm, T-0.40H, HiOs, T1.30H, MG 150, S0" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S836" upshifts 2191372 /Source="Nicolas_upshifts" /id="U1735" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.93906093906094" /psig=1 /xcortree=3227 /SigmaFactorBS="gaagagtttttttaataatatgtcaattcattattttttCGT TGACTcttttcactatttaTCCTAAAATTTTCTTTGAAAccgttaccaaaatattttc a" /listShort="S836, kduI, kduD" /GFF_Attribute="listLong" promotor_-10 2191373..2191392 /Source="Nicolas_upshift_promotors" /id="U1735" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.93906093906094" /psig=1 /xcortree=3227 /SigmaFactorBS="gaagagtttttttaataatatgtcaattcattattttttCGT TGACTcttttcactatttaTCCTAAAATTTTCTTTGAAAccgttaccaaaatattttc a" /listShort="S836, kduI, kduD" /GFF_Attribute="listLong" /label="promotor_-10" CDS 2191452..2192279 /gene="kduI" /locus_tag="BSU_22130" /old_locus_tag="BSU22130" /EC_number="5.3.1.17" /function="16.2: Construct biomass (Anabolism)" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 15528647, 23437267, 27227414; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase, 5-keto-4-deoxyuronate isomerase" /protein_id="NP_390095.1" /db_xref="EnsemblGenomes-Gn:BSU22130" /db_xref="EnsemblGenomes-Tr:CAB14130" /db_xref="GOA:P50843" /db_xref="InterPro:IPR007045" /db_xref="InterPro:IPR011051" /db_xref="InterPro:IPR014710" /db_xref="InterPro:IPR021120" /db_xref="InterPro:IPR027449" /db_xref="SubtiList:BG11401" /db_xref="UniProtKB/Swiss-Prot:P50843" /translation="MENRYSVHPEQVKRFTTEELRSHFLMDSLFTENKLTMYYSHEDR VVIGGAAPGQSELKLDAGDFLKTDFFLERREIGIINVGQPGAVRVGDDEYVLQTKDFL YIGMGNQDVSFSSLNGEKAKFYFVSACAHKSYPTQKAALSELTPDRLGDDAASNVRSL YKVIHQDGIKSCQLMMGITMLDQNNNWNTMPAHVHDRRMEAYLYLDLEKDSKVFHFMG QPDETRHLVVGNEQAVLSPAWSIHSGAGTSNYSFVWAMAGENYTFTDMDLIPMDGLK* " gene 2191452..2192279 /gene="kduI" /locus_tag="BSU_22130" /old_locus_tag="BSU22130" CDS 2192281..2193045 /gene="kduD" /locus_tag="BSU_22140" /old_locus_tag="BSU22140" /EC_number="1.1.1.127" /function="16.11: Scavenge (Catabolism)" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 15528647, 24509771, 27028675; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="2-keto-3-deoxygluconate oxidoreductase" /protein_id="NP_390096.1" /db_xref="EnsemblGenomes-Gn:BSU22140" /db_xref="EnsemblGenomes-Tr:CAB14131" /db_xref="GOA:P50842" /db_xref="InterPro:IPR002347" /db_xref="InterPro:IPR011286" /db_xref="InterPro:IPR020904" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG11400" /db_xref="UniProtKB/Swiss-Prot:P50842" /translation="MGYLHDAFSLKGKTALVTGPGTGIGQGIAKALAGAGADIIGTSH TSSLSETQQLVEQEGRIFTSFTLDMSKPEAIKDSAAELFENRQIDILVNNAGIIHREK AEDFPEENWQHVLNVNLNSLFILTQLAGRHMLKRGHGKIINIASLLSFQGGILVPAYT ASKHAVAGLTKSFANEWAASGIQVNAIAPGYISTANTKPIRDDEKRNEDILKRIPAGR WGQADDIGGTAVFLASRASDYVNGHILAVDGGWLSR*" gene 2192281..2193045 /gene="kduD" /locus_tag="BSU_22140" /old_locus_tag="BSU22140" downshifts 2193034 /Source="Nicolas_upshifts" /id="D1160" /incds=0 /nref=12 /ntot=160 /MaxReadThrough="0.66029" /MaxDrop="3.56178" /score="23.0070487" /energy="-12.3" /TU="NA" /idTUdmin="U1735" /TUdmin=0 /isTUend="TRUE" downshifts complement(2193076) /Source="Nicolas_upshifts" /id="D1161" /incds=0 /nref=28 /ntot=225 /MaxReadThrough="1.88107" /MaxDrop="5.27501" /score="35.5168663" /energy="-12.3" /TU="NA" /idTUdmin="U1736" /TUdmin="-10" /isTUend="TRUE" CDS complement(2193086..2195011) /gene="ypvA" /locus_tag="BSU_22150" /old_locus_tag="BSU22150" /EC_number="3.6.1.-" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 8385320, 17114254; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative ATP-dependent helicase" /protein_id="NP_390097.1" /db_xref="EnsemblGenomes-Gn:BSU22150" /db_xref="EnsemblGenomes-Tr:CAB14132" /db_xref="GOA:P50831" /db_xref="InterPro:IPR006555" /db_xref="InterPro:IPR014013" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG11457" /db_xref="UniProtKB/Swiss-Prot:P50831" /translation="MTTSRLPFSLTKTKNFYEELNNWIGDVFYDILPEKGFDLRDEQV FMAFQLERAFKEKKVMFAEAGVGTGKTLVYLLFAISYARYVGKPAIIACADETLIEQL VKKEGDISKLAEHLDLKIDTRLSKSHEQYLCLKKLEKTMQRSDDDKWLDLYESLPSFV HESQAMQRFYPYGDRKQYANLSNEEWSDVSYDSFQDCLTCDMRHRCGLTLSRDYYRKS TDLIICSHDFYMEHVWTEESRKREGQLPLLPDHSAVVFDEGHLLEFAAQKALTYRVKQ STLELFLERLLQNDIREEFAELIEDALLANDEFFYVLSEESKEVAGSHRLEIKNDHRV KKAADELCRLLDKIGEALVFESEMYTIDQYELSVVEEYVEQMAYSLSLYQKDAISWLE KKEAESTFVVMPRTVAEVLGEKVFSKKIPYIFSSATLSEGGSFDYIADSLGIHDYLSL TVDSPYDYDEQMSINLYAKTDMDAEQKTAETIETIKRYKGRTLVLFPSFEELNEFKEL SAAWELPYPIFFEGDEEISSLVEKFQEEEETVLCSVHLWEGLDIPGDALKNVTIWSLP FPPHDPVFTAKRNGAKKDPFEEVDLPYMLLRVRQGIGRLIRSNQDSGSIHIYAGGENE RIIDEVKKVLPVEPHMM*" gene complement(2193086..2195011) /gene="ypvA" /locus_tag="BSU_22150" /old_locus_tag="BSU22150" promotor_-10 complement(2195042..2195061) /Source="Nicolas_upshift_promotors" /id="U1736" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.53946053946054" /psig=1 /xcortree=2498 /SigmaFactorBS="aaaaacttggcattgccaagttttttATTGTattcatcagcg gaaAATGATATTATTGGTGGTCTgaatgtcgaatagttgggggttggaactaggtgac a" /listShort="ypvA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2195046) /Source="Nicolas_upshifts" /id="U1736" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.53946053946054" /psig=1 /xcortree=2498 /SigmaFactorBS="aaaaacttggcattgccaagttttttATTGTattcatcagcg gaaAATGATATTATTGGTGGTCTgaatgtcgaatagttgggggttggaactaggtgac a" /listShort="ypvA" /GFF_Attribute="listLong" S_feature complement(2195048..2195112) /Source="Nicolas_S_feature" /locus_tag="new_2329450_2329514_c" /HighExp="S3, S4, S8, S7, LoTm, S5, S6, BT, G180, Cold" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigEF, SigA" /TUshortPSig="0.999, 1" /TUlongSig="SigA, SigA, SigA, SigA" /TUlongPSig="0.998, 1, 0.998, 1" /label="S837" promotor_-35 complement(2195076..2195080) /Source="Nicolas_upshift_promotors" /id="U1736" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.53946053946054" /psig=1 /xcortree=2498 /SigmaFactorBS="aaaaacttggcattgccaagttttttATTGTattcatcagcg gaaAATGATATTATTGGTGGTCTgaatgtcgaatagttgggggttggaactaggtgac a" /listShort="ypvA" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2195113..2195304) /gene="yptA" /locus_tag="BSU_22160" /old_locus_tag="BSU22160" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="NP_390098.1" /db_xref="EnsemblGenomes-Gn:BSU22160" /db_xref="EnsemblGenomes-Tr:CAB14133" /db_xref="SubtiList:BG11456" /db_xref="UniProtKB/Swiss-Prot:P50841" /translation="MLNSEHFNLIQRALDATANELKELGTDSSPSVISHAQTDLEKAV EHIYSTDHPFLSSHVINRK*" gene complement(2195113..2195304) /gene="yptA" /locus_tag="BSU_22160" /old_locus_tag="BSU22160" promotor_-10 complement(2195323..2195341) /Source="Nicolas_upshift_promotors" /id="U1737" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1119 /SigmaFactorBS="catgtttcggtgataacatgcggtaaagcaTGTATAtaaaat gaaaagttcGCATACAATGATGATTATTtccatcagaggtgatctcatgctgaacagc g" /listShort="yptA, S837, ypvA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2195332) /Source="Nicolas_upshifts" /id="U1737" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1119 /SigmaFactorBS="catgtttcggtgataacatgcggtaaagcaTGTATAtaaaat gaaaagttcGCATACAATGATGATTATTtccatcagaggtgatctcatgctgaacagc g" /listShort="yptA, S837, ypvA" /GFF_Attribute="listLong" S_feature complement(2195334..2195639) /Source="Nicolas_S_feature" /locus_tag="new_2329736_2330041_c" /HighExp="Cold, G135, G180, C30, G150, Oxctl, Paraq, H2O2, LBGstat, LPh" /AntisenseName="ypzG" /AntisenseCor="-0.39420155633160697" /AntisenseRegPval="-10.7" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="SigA, SigA, SigA, SigA" /TUlongPSig="0.998, 1, 0.998, 1" /label="S838" promotor_-35 complement(2195357..2195362) /Source="Nicolas_upshift_promotors" /id="U1737" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1119 /SigmaFactorBS="catgtttcggtgataacatgcggtaaagcaTGTATAtaaaat gaaaagttcGCATACAATGATGATTATTtccatcagaggtgatctcatgctgaacagc g" /listShort="yptA, S837, ypvA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 2195371..2195377 /Source="Nicolas_upshift_promotors" /id="U1738" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=859 /SigmaFactorBS="cgaacttttcattttatatacatgctttacCGCATGTtatca ccgaaacatGCACAAACTACActtgatattccgtctccggattatccgtcttatcaac a" /listShort="ypzG" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2195392..2195403 /Source="Nicolas_upshift_promotors" /id="U1738" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=859 /SigmaFactorBS="cgaacttttcattttatatacatgctttacCGCATGTtatca ccgaaacatGCACAAACTACActtgatattccgtctccggattatccgtcttatcaac a" /listShort="ypzG" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2195401 /Source="Nicolas_upshifts" /id="U1738" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=859 /SigmaFactorBS="cgaacttttcattttatatacatgctttacCGCATGTtatca ccgaaacatGCACAAACTACActtgatattccgtctccggattatccgtcttatcaac a" /listShort="ypzG" /GFF_Attribute="listLong" CDS 2195468..2195620 /gene="ypzG" /locus_tag="BSU_22169" /old_locus_tag="BSU22169" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="YP_003097754.1" /db_xref="EnsemblGenomes-Gn:BSU22169" /db_xref="EnsemblGenomes-Tr:CAX52653" /db_xref="InterPro:IPR025413" /db_xref="UniProtKB/Swiss-Prot:C0H444" /translation="MSYRNRLDQHSELFHHNWTRPKRSKSQVNGHTEMSQTNIILRSN AKAHRW*" gene 2195468..2195620 /gene="ypzG" /locus_tag="BSU_22169" /old_locus_tag="BSU22169" downshifts 2195630 /Source="Nicolas_upshifts" /id="D1162" /incds=0 /nref=35 /ntot=65 /MaxReadThrough="1.2837" /MaxDrop="7.64655" /score="-9.36260071" /energy="-16.3" /TU="NA" /idTUdmin="U1738" /TUdmin=0 /isTUend="TRUE" CDS complement(2195673..2196830) /gene="rlmKB" /locus_tag="BSU_22170" /old_locus_tag="BSU22170" /EC_number="2.1.1.264" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 22210896, 22362734; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="m(7)G2069 methylase of 23S rRNA" /protein_id="NP_390099.1" /db_xref="EnsemblGenomes-Gn:BSU22170" /db_xref="EnsemblGenomes-Tr:CAB14134" /db_xref="GOA:P50840" /db_xref="InterPro:IPR000241" /db_xref="InterPro:IPR002052" /db_xref="InterPro:IPR004114" /db_xref="InterPro:IPR029063" /db_xref="SubtiList:BG11455" /db_xref="UniProtKB/Swiss-Prot:P50840" /translation="MKKYTLIATAPMGIEAVVAKEVRDLGYECKVDNGKVIFEGDALA ICRANLWLRTADRIKVQVASFKAKTFDELFEKTKAINWRSFIPENGKFPVIGKSVKST LASVPDCQRIVKKAIVEKLKLQSGKANDWIEETGAEYKVEISLLKDQALITLDSSGTG LHKRGYRVDQGGAPIKETLAAALVQLTNWTPDRPFVDPFCGSGTIAIEAALIGQNIAP GFNRDFVSEDWEWIGKDLWNKARLEVEEKANYDQPLTIFASDIDHRMVQIAKENAEEA GLGDLIQFKQMQVKDFTTNLEFGVIVGNPPYGERLGEKKAVEQMYKEMGQAFEPLDTW SVYMLTSNENFEEAYGRKATKKRKLFNGFIKTDYYQYWSKVRPQRKKTENA*" gene complement(2195673..2196830) /gene="rlmKB" /locus_tag="BSU_22170" /old_locus_tag="BSU22170" downshifts complement(2195684) /Source="Nicolas_upshifts" /id="D1163" /incds=0 /nref=86 /ntot=240 /MaxReadThrough="4.31441" /MaxDrop="4.58268" /score="14.6684819" /energy="-6.2" /TU="U1739" /idTUdmin="U1740" /TUdmin=0 /isTUend="TRUE" misc_RNA complement(2196918..2197318) /gene="rnpB" /locus_tag="BSU_misc_RNA_35" /product="RNA component of ribonuclease P (RNase P) (catalytic subunit, ribozyme)" /experiment="publication(s) with functional evidences, PMID:1699929, 16980484, 17919279, 22448220" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1699929, 16980484, 17919279, 22448220; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene complement(2196918..2197318) /gene="rnpB" /locus_tag="BSU_misc_RNA_35" downshifts complement(2196928) /Source="Nicolas_upshifts" /id="D1164" /incds=0 /nref=200 /ntot=276 /MaxReadThrough="6.17541" /MaxDrop="7.4677" /score="0.20729905" /energy="-10.4" /TU="U1739,U1740" /idTUdmin="U1742" /TUdmin=406 /isTUend="FALSE" promotor_-10 complement(2197315..2197334) /Source="Nicolas_upshift_promotors" /id="U1739" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.684315684315684" /psig=1 /xcortree=288 /SigmaFactorBS="gcaagctttatgattgatcacgcttgaaaaaaatggcgCTTG TAAattgtaatcagttgTTATATAATAATTCATGTTCttaacgttcgggtaatcgctg c" /listShort="rnpB, ypsC, S838, yptA, S837, ypvA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2197333) /Source="Nicolas_upshifts" /id="U1739" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.684315684315684" /psig=1 /xcortree=288 /SigmaFactorBS="gcaagctttatgattgatcacgcttgaaaaaaatggcgCTTG TAAattgtaatcagttgTTATATAATAATTCATGTTCttaacgttcgggtaatcgctg c" /listShort="rnpB, ypsC, S838, yptA, S837, ypvA" /GFF_Attribute="listLong" promotor_-35 complement(2197349..2197355) /Source="Nicolas_upshift_promotors" /id="U1739" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.684315684315684" /psig=1 /xcortree=288 /SigmaFactorBS="gcaagctttatgattgatcacgcttgaaaaaaatggcgCTTG TAAattgtaatcagttgTTATATAATAATTCATGTTCttaacgttcgggtaatcgctg c" /listShort="rnpB, ypsC, S838, yptA, S837, ypvA" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2197377..2197673) /gene="gpsB" /locus_tag="BSU_22180" /old_locus_tag="BSU22180" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:18363795, 18776011, 19429628, 25845974, 27257764" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 18363795, 18776011, 19429628, 25845974, 27257764; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="cell division protein" /protein_id="NP_390100.1" /db_xref="EnsemblGenomes-Gn:BSU22180" /db_xref="EnsemblGenomes-Tr:CAB14135" /db_xref="GOA:P0CI74" /db_xref="InterPro:IPR007793" /db_xref="InterPro:IPR011229" /db_xref="InterPro:IPR019933" /db_xref="PDB:4UG3" /db_xref="PDB:5AN5" /db_xref="SubtiList:BG11454" /db_xref="UniProtKB/Swiss-Prot:P0CI74" /translation="MLADKVKLSAKEILEKEFKTGVRGYKQEDVDKFLDMIIKDYETF HQEIEELQQENLQLKKQLEEASKKQPVQSNTTNFDILKRLSNLEKHVFGSKLYD*" gene complement(2197377..2197673) /gene="gpsB" /locus_tag="BSU_22180" /old_locus_tag="BSU22180" promotor_-10 complement(2197698..2197717) /Source="Nicolas_upshift_promotors" /id="U1740" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.712287712287712" /psig="0.998001998001998" /xcortree=3143 /SigmaFactorBS="gaggaagacagctactaacaatgagagagaAATTTGACaacc gtacagattTCTGAAAAAATATATGTGATgattcacgatacgaggtgaaaaagatgct t" /listShort="gpsB, rnpB, ypsC" /listLong="S838, yptA, S837, ypvA" /label="promotor_-10" upshifts complement(2197708) /Source="Nicolas_upshifts" /id="U1740" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.712287712287712" /psig="0.998001998001998" /xcortree=3143 /SigmaFactorBS="gaggaagacagctactaacaatgagagagaAATTTGACaacc gtacagattTCTGAAAAAATATATGTGATgattcacgatacgaggtgaaaaagatgct t" /listShort="gpsB, rnpB, ypsC" /listLong="S838, yptA, S837, ypvA" promotor_-35 complement(2197731..2197738) /Source="Nicolas_upshift_promotors" /id="U1740" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.712287712287712" /psig="0.998001998001998" /xcortree=3143 /SigmaFactorBS="gaggaagacagctactaacaatgagagagaAATTTGACaacc gtacagattTCTGAAAAAATATATGTGATgattcacgatacgaggtgaaaaagatgct t" /listShort="gpsB, rnpB, ypsC" /listLong="S838, yptA, S837, ypvA" /label="promotor_-35" CDS complement(2197751..2198380) /gene="ypsA" /locus_tag="BSU_22190" /old_locus_tag="BSU22190" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_390101.2" /db_xref="EnsemblGenomes-Gn:BSU22190" /db_xref="EnsemblGenomes-Tr:CAB14136" /db_xref="InterPro:IPR010697" /db_xref="PDB:2NX2" /db_xref="SubtiList:BG11453" /db_xref="UniProtKB/Swiss-Prot:P50838" /translation="MENVQLDGVNNAAQQMGPTGAPFFKAGEMMKVLAITGYKPFELG IFKQDDKALYYIKKAIKNRLIAFLDEGLEWILISGQLGVELWAAEAAYDLQEEYPDLK VAVITPFYEQEKNWKEPNKEQYEAVLAQADYEASLTHRPYESPLQFKQKNQFFIDKSD GLLLLYDPEKEGSPKYMLGTAEKRREQDGYPIYFITMDDLRVTVEEDSY*" gene complement(2197751..2198380) /gene="ypsA" /locus_tag="BSU_22190" /old_locus_tag="BSU22190" downshifts complement(2198346) /Source="Nicolas_upshifts" /id="D1165" /incds=0 /nref=37 /ntot=160 /MaxReadThrough="5.74028" /MaxDrop="8.12374" /score="7.18626302" /energy="-9.8" /TU="U1741,U1742" /idTUdmin="U1744" /TUdmin=0 /isTUend="TRUE" CDS complement(2198382..2198609) /gene="cotD" /locus_tag="BSU_22200" /old_locus_tag="BSU22200" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:2821284, 10075739, 10400595, 1518043, 1691789, 19933362" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 2821284, 10075739, 10400595, 1518043, 1691789, 19933362; Product type cp : cell process" /codon_start=1 /transl_table=11 /product="spore coat protein (inner)" /protein_id="NP_390102.1" /db_xref="EnsemblGenomes-Gn:BSU22200" /db_xref="EnsemblGenomes-Tr:CAB14137" /db_xref="GOA:P07791" /db_xref="InterPro:IPR020108" /db_xref="SubtiList:BG10493" /db_xref="UniProtKB/Swiss-Prot:P07791" /translation="MHHCRPHMMAPIVHPTHCCEHHTFSKTIVPHIHPQHTTNVNHQH FQHVHYFPHTFSNVDPATHQHFQAGKPCCDY*" gene complement(2198382..2198609) /gene="cotD" /locus_tag="BSU_22200" /old_locus_tag="BSU22200" promotor_-10 complement(2198637..2198656) /Source="Nicolas_upshift_promotors" /id="U1741" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp="0.948051948051948" /psig="0.948051948051948" /xcortree=1359 /SigmaFactorBS="gcttaattgcacacttttaaaataggtctttgcaTCAGAACA TgtaccccttatttTTCATAACTTAGTATTGTAAtaaagtttatggaaaggggatttt a" /listShort="cotD, ypsA" /listLong="gpsB, rnpB, ypsC" /label="promotor_-10" upshifts complement(2198652) /Source="Nicolas_upshifts" /id="U1741" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp="0.948051948051948" /psig="0.948051948051948" /xcortree=1359 /SigmaFactorBS="gcttaattgcacacttttaaaataggtctttgcaTCAGAACA TgtaccccttatttTTCATAACTTAGTATTGTAAtaaagtttatggaaaggggatttt a" /listShort="cotD, ypsA" /listLong="gpsB, rnpB, ypsC" S_feature complement(2198654..2198808) /Source="Nicolas_S_feature" /locus_tag="new_2333056_2333210_c" /HighExp="LBGexp, dia15, Paraq, H2O2, Heat, G135, UNK1, Lbexp, BMM, HiTm" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.808141" /TUshortSig="SigA, Sig-, SigA, SigA" /TUshortPSig="1, 0.419, 0.998, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S839" promotor_-35 complement(2198670..2198678) /Source="Nicolas_upshift_promotors" /id="U1741" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp="0.948051948051948" /psig="0.948051948051948" /xcortree=1359 /SigmaFactorBS="gcttaattgcacacttttaaaataggtctttgcaTCAGAACA TgtaccccttatttTTCATAACTTAGTATTGTAAtaaagtttatggaaaggggatttt a" /listShort="cotD, ypsA" /listLong="gpsB, rnpB, ypsC" /label="promotor_-35" CDS complement(2198693..2198821) /locus_tag="BSU_22205" /old_locus_tag="BSU22205" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="YP_009513975.1" /translation="MTLVIFKGRVGMYKGVFYLFFVVVFLIAFVFSNFKDSLIAHF*" gene complement(2198693..2198821) /locus_tag="BSU_22205" /old_locus_tag="BSU22205" upshifts complement(2198808) /Source="Nicolas_upshifts" /id="U1742" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.592407592407592" /psig=1 /xcortree=2670 /SigmaFactorBS="ctgaattcacattgatttTGTTGtagaatagcggcgaaTCCT GTAAAATGACGTTAGTtatttttaaagggagagttggtatgtataagggtgtttttta c" /listShort="S839, cotD, ypsA, gpsB" /listLong="rnpB, ypsC, S838, yptA, S837, ypvA" S_feature complement(2198810..2198921) /Source="Nicolas_S_feature" /locus_tag="new_2333212_2333323_c" /HighExp="Sw, M40t90, Etha, Salt, M40t45, H2O2, S8, S6, G135, G180" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="Sig-, SigA, SigA" /TUshortPSig="0.419, 0.998, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S840" promotor_-10 complement(2198811..2198830) /Source="Nicolas_upshift_promotors" /id="U1742" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.592407592407592" /psig=1 /xcortree=2670 /SigmaFactorBS="ctgaattcacattgatttTGTTGtagaatagcggcgaaTCCT GTAAAATGACGTTAGTtatttttaaagggagagttggtatgtataagggtgtttttta c" /listShort="S839, cotD, ypsA, gpsB" /listLong="rnpB, ypsC, S838, yptA, S837, ypvA" /label="promotor_-10" promotor_-35 complement(2198846..2198850) /Source="Nicolas_upshift_promotors" /id="U1742" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.592407592407592" /psig=1 /xcortree=2670 /SigmaFactorBS="ctgaattcacattgatttTGTTGtagaatagcggcgaaTCCT GTAAAATGACGTTAGTtatttttaaagggagagttggtatgtataagggtgtttttta c" /listShort="S839, cotD, ypsA, gpsB" /listLong="rnpB, ypsC, S838, yptA, S837, ypvA" /label="promotor_-35" CDS complement(2198922..2200163) /gene="yprB" /locus_tag="BSU_22210" /old_locus_tag="BSU22210" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 23249255; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative nucleic acid binding enzyme" /protein_id="NP_390103.1" /db_xref="EnsemblGenomes-Gn:BSU22210" /db_xref="EnsemblGenomes-Tr:CAB14138" /db_xref="GOA:P50837" /db_xref="InterPro:IPR011990" /db_xref="InterPro:IPR012337" /db_xref="InterPro:IPR036397" /db_xref="SubtiList:BG11452" /db_xref="UniProtKB/Swiss-Prot:P50837" /translation="MSLKGKLQRMKKHMALDEGEQKIEAGKQENHFDDIPFLEEWEAF GMKPFIFEDEYCLIREVEYPLSHRHGLYSFSELEEVITLWNQSGLSHTLSAKGYNKNN LFFFDTETTGLGGGAGNTIFLLGHARVYEDRVTVKQHLLPKPGNEVALYQSFLSEVDI TSLVTYNGKAFDWPQVKTRHTLIRDRLPKLPEFGHFDLLHGARRLWKHKMDRVSLGTV EKEELGIRRLEDTPGYLAPMLYFHFIKAQEPDLLKGVLHHNEMDVLSLISLYIHMSKK ILSESHAPKEHSEAYAMAKWFMAHKETDQAIKQLERLIEKSFEDQDSARLDLSLLYKK QNRLEEAVPLWEKLSRSQNQKCRYAAVIELAKYFEHKKKEFGKALQVAEQSLSDAACL SEKETEKLHVRIARLKRKYSS*" gene complement(2198922..2200163) /gene="yprB" /locus_tag="BSU_22210" /old_locus_tag="BSU22210" promotor_-10 complement(2199877..2199895) /Source="Nicolas_upshift_promotors" /id="U1743" /multdbtbs="-" /comp="M5" /sig="Sig-" /pcomp="0.418581418581419" /psig="0.418581418581419" /xcortree=723 /SigmaFactorBS="gcttttctgagcttgaggaagtgatcacaCTGTGGAAtcaaa gcggcctgtCGCATACATTGTCAGCAAAagggtataacaaaaacaacctctttttctt t" /listShort="S840, S839" /listLong="cotD" /label="promotor_-10" upshifts complement(2199886) /Source="Nicolas_upshifts" /id="U1743" /multdbtbs="-" /comp="M5" /sig="Sig-" /pcomp="0.418581418581419" /psig="0.418581418581419" /xcortree=723 /SigmaFactorBS="gcttttctgagcttgaggaagtgatcacaCTGTGGAAtcaaa gcggcctgtCGCATACATTGTCAGCAAAagggtataacaaaaacaacctctttttctt t" /listShort="S840, S839" /listLong="cotD" promotor_-35 complement(2199910..2199917) /Source="Nicolas_upshift_promotors" /id="U1743" /multdbtbs="-" /comp="M5" /sig="Sig-" /pcomp="0.418581418581419" /psig="0.418581418581419" /xcortree=723 /SigmaFactorBS="gcttttctgagcttgaggaagtgatcacaCTGTGGAAtcaaa gcggcctgtCGCATACATTGTCAGCAAAagggtataacaaaaacaacctctttttctt t" /listShort="S840, S839" /listLong="cotD" /label="promotor_-35" CDS complement(2200179..2202428) /gene="yprA" /locus_tag="BSU_22220" /old_locus_tag="BSU22220" /EC_number="3.6.4.-" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 16267290; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative ATP-dependent RNA helicase" /protein_id="NP_390104.1" /db_xref="EnsemblGenomes-Gn:BSU22220" /db_xref="EnsemblGenomes-Tr:CAB14139" /db_xref="GOA:P50830" /db_xref="InterPro:IPR001650" /db_xref="InterPro:IPR011545" /db_xref="InterPro:IPR014001" /db_xref="InterPro:IPR018973" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG11451" /db_xref="UniProtKB/Swiss-Prot:P50830" /translation="MKKKSLTELISDLKGNENVVNWHEIEPREAKTRPMPESIDERIK AALSKRGIDELYTHQYSAFQYVQKGESIVTVTPTASGKTLCYNLPVLQSIAQDETNRA LYLFPTKALAQDQKSELNEIIDEMGIDIKSFTYDGDTSPAIRQKVRKAGHIVITNPDM LHSAILPHHTKWVSLFENLKYIVIDELHTYRGVFGSHVANVIRRLKRICRFYGSDPVF ICTSATIANPKELGEQLTGKPMRLVDDNGAPSGRKHFVFYNPPIVNKPLNIRRSATAE VNELAKEFLKNKVQTIVFARSRVRVEIILSHIQELVKKEIGTKSIRGYRGGYLPKERR EIERGLREGDILGVVSTNALELGVDIGQLQVCVMTGYPGSVASAWQQAGRAGRRHGES LIIMVANSTPIDQYIVRHPEYFFNRSPESARINPENLIILVDHLKCAAYELPFRADEE FGAMEVSDILEYLQEEAVLHRNGERYHWASESFPASNISLRSASQENVVIVDQSDIAN VRIIGEMDRFSAMTLLHDEAIYLHEGVQYQVEKLDWDHKKAYVRKVDVEYYTDANLAV QLKVLEIDKTKEKSRTSLHYGDVTVNALPTIFKKIKMTTFENIGSGPIHLPEEELHTS AAWLEIKTADEDIGEKTLEQLLLGISNVLQHIVPVYIMCDRNDVHVVSQIKAAHTGLP TIFLYDHYPGGIGLAEEVFKRFSDINEAAKQLITHCPCHDGCPSCIGTEIEGIKAKER ILQLLDQMS*" gene complement(2200179..2202428) /gene="yprA" /locus_tag="BSU_22220" /old_locus_tag="BSU22220" promotor_-10 complement(2202444..2202463) /Source="Nicolas_upshift_promotors" /id="U1744" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.362637362637363" /psig="0.998001998001998" /xcortree=2675 /SigmaFactorBS="tgccttgctttttttattcaactgtataaaatttgcaCCTAG CCatgcaaacaaataTTCGGTAAACTGTACTTGACaaagaggtgtaaagaatgaaaaa g" /listShort="yprA, yprB, S840, S839, cotD" /listLong="ypsA, gpsB, rnpB, ypsC, S838, yptA, S837, ypvA" /label="promotor_-10" upshifts complement(2202460) /Source="Nicolas_upshifts" /id="U1744" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.362637362637363" /psig="0.998001998001998" /xcortree=2675 /SigmaFactorBS="tgccttgctttttttattcaactgtataaaatttgcaCCTAG CCatgcaaacaaataTTCGGTAAACTGTACTTGACaaagaggtgtaaagaatgaaaaa g" /listShort="yprA, yprB, S840, S839, cotD" /listLong="ypsA, gpsB, rnpB, ypsC, S838, yptA, S837, ypvA" promotor_-35 complement(2202477..2202483) /Source="Nicolas_upshift_promotors" /id="U1744" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.362637362637363" /psig="0.998001998001998" /xcortree=2675 /SigmaFactorBS="tgccttgctttttttattcaactgtataaaatttgcaCCTAG CCatgcaaacaaataTTCGGTAAACTGTACTTGACaaagaggtgtaaagaatgaaaaa g" /listShort="yprA, yprB, S840, S839, cotD" /listLong="ypsA, gpsB, rnpB, ypsC, S838, yptA, S837, ypvA" /label="promotor_-35" CDS complement(2202531..2203037) /gene="ypqE" /locus_tag="BSU_22230" /old_locus_tag="BSU22230" /EC_number="2.7.1.-" /function="16.1: Circulate" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 10627040, 28731580; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative phosphotransferase system enzyme IIA component" /protein_id="NP_390105.1" /db_xref="EnsemblGenomes-Gn:BSU22230" /db_xref="EnsemblGenomes-Tr:CAB14140" /db_xref="GOA:P50829" /db_xref="InterPro:IPR001127" /db_xref="InterPro:IPR011055" /db_xref="SubtiList:BG11450" /db_xref="UniProtKB/Swiss-Prot:P50829" /translation="MLKKLFGMGKIQEKVTEEVIYSPADGTVMDLSDVPDPVFSQKMM GEGIAVEPSSGEIVSPAEGEVIQIFHTKHAVGIRTRSGIELLIHVGLETVNMNGEGFT AHIKEGDKVKVGDPLITCDLELIKEKASSTVIPIVIMNGEAVGSMVSAGEKAARKGES KLFTIKAK*" gene complement(2202531..2203037) /gene="ypqE" /locus_tag="BSU_22230" /old_locus_tag="BSU22230" downshifts complement(2202554) /Source="Nicolas_upshifts" /id="D1166" /incds=0 /nref=88 /ntot=236 /MaxReadThrough="4.55156" /MaxDrop="6.1724" /score="32.5355561" /energy="-10.2" /TU="U1745" /idTUdmin="U1747" /TUdmin=808 /isTUend="FALSE" promotor_-10 complement(2203081..2203100) /Source="Nicolas_upshift_promotors" /id="U1745" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.704295704295704" /psig=1 /xcortree=3134 /SigmaFactorBS="tttaaccagattatgcgtctatgccagatgttgttatAAATT GAAgcaaaattgaaagTGTGGTTAAATAGTGGTGAAtgaagggataacggttgaagtg a" /listShort="ypqE, yprA, yprB, S840, S839, cotD" /listLong="ypsA, gpsB, rnpB, ypsC, S838, yptA, S837, ypvA" /label="promotor_-10" upshifts complement(2203098) /Source="Nicolas_upshifts" /id="U1745" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.704295704295704" /psig=1 /xcortree=3134 /SigmaFactorBS="tttaaccagattatgcgtctatgccagatgttgttatAAATT GAAgcaaaattgaaagTGTGGTTAAATAGTGGTGAAtgaagggataacggttgaagtg a" /listShort="ypqE, yprA, yprB, S840, S839, cotD" /listLong="ypsA, gpsB, rnpB, ypsC, S838, yptA, S837, ypvA" promotor_-35 complement(2203114..2203121) /Source="Nicolas_upshift_promotors" /id="U1745" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.704295704295704" /psig=1 /xcortree=3134 /SigmaFactorBS="tttaaccagattatgcgtctatgccagatgttgttatAAATT GAAgcaaaattgaaagTGTGGTTAAATAGTGGTGAAtgaagggataacggttgaagtg a" /listShort="ypqE, yprA, yprB, S840, S839, cotD" /listLong="ypsA, gpsB, rnpB, ypsC, S838, yptA, S837, ypvA" /label="promotor_-35" promotor_-35 2203119..2203128 /Source="Nicolas_upshift_promotors" /id="U1746" /multdbtbs="SigE,SigK" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1340 /SigmaFactorBS="aaccacactttcaattttgcttcaaTTTATAACAAcatctgg catagaCGCATAATCTGGTTAAAAAAggcggtggcgatattggaattccatgatgaca a" /listShort="ypqA, S841" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2203142..2203161 /Source="Nicolas_upshift_promotors" /id="U1746" /multdbtbs="SigE,SigK" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1340 /SigmaFactorBS="aaccacactttcaattttgcttcaaTTTATAACAAcatctgg catagaCGCATAATCTGGTTAAAAAAggcggtggcgatattggaattccatgatgaca a" /listShort="ypqA, S841" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2203154 /Source="Nicolas_upshifts" /id="U1746" /multdbtbs="SigE,SigK" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1340 /SigmaFactorBS="aaccacactttcaattttgcttcaaTTTATAACAAcatctgg catagaCGCATAATCTGGTTAAAAAAggcggtggcgatattggaattccatgatgaca a" /listShort="ypqA, S841" /GFF_Attribute="listLong" CDS 2203175..2203594 /gene="ypqA" /locus_tag="BSU_22240" /old_locus_tag="BSU22240" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type f: factor" /codon_start=1 /transl_table=11 /product="putative chaperone" /protein_id="NP_390106.1" /db_xref="EnsemblGenomes-Gn:BSU22240" /db_xref="EnsemblGenomes-Tr:CAB14141" /db_xref="InterPro:IPR008978" /db_xref="SubtiList:BG11449" /db_xref="UniProtKB/Swiss-Prot:P50836" /translation="MEFHDDKKNELQKKEEIITEAIDTLFQSSAFGNLINGFQNLINS SLKDVQTTIHVRERDTGLYIDITIPATFRDGEIVVDVKSRYLHVTLQEKQKHQNEATF TSMTRTVQLPYEVRQEDMETSWNEQTMTLFFPKNKHE*" gene 2203175..2203594 /gene="ypqA" /locus_tag="BSU_22240" /old_locus_tag="BSU22240" S_feature 2203595..2203745 /Source="Nicolas_S_feature" /locus_tag="new_2337997_2338147" /HighExp="S6, S8, S7, BT, S5, B36, B60, Pyr, G/S, nit" /AntisenseName="yppG" /AntisenseCor="0.95679380325708796" /AntisenseRegPval="-144.5" /CDS_PredictionProba="NA" /TUshortSig="SigK" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S841" CDS complement(2203615..2203992) /gene="yppG" /locus_tag="BSU_22250" /old_locus_tag="BSU22250" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 22882546; Product type s: structure" /codon_start=1 /transl_table=11 /product="putative spore coat protein; methionine-glutamine-rich protein" /protein_id="NP_390107.1" /db_xref="EnsemblGenomes-Gn:BSU22250" /db_xref="EnsemblGenomes-Tr:CAB14142" /db_xref="InterPro:IPR025555" /db_xref="SubtiList:BG11448" /db_xref="UniProtKB/Swiss-Prot:P50835" /translation="MNGSSRSYPRQMGYYYPQHMQGYYQQAAPGYLEQQLPQQHYGQQ DYYQPYAPIQPMPMQPPVFSNPYPIPRPNQQQPSQFQSIMSQFKKANGQFDFNKMMDT TGQVMSAMNQVGSLIKGFTSFFK*" gene complement(2203615..2203992) /gene="yppG" /locus_tag="BSU_22250" /old_locus_tag="BSU22250" downshifts complement(2203648) /Source="Nicolas_upshifts" /id="D1167" /incds=0 /nref=10 /ntot=43 /MaxReadThrough="3.01854" /MaxDrop="4.7006" /score="0.85617333" /energy="-12.8" /TU="U1747" /idTUdmin="U1747" /TUdmin="-286" /isTUend="FALSE" S_feature 2203990..2204135 /Source="Nicolas_S_feature" /locus_tag="new_2338392_2338537" /HighExp="S6, S8, S7, BT, S5, B36, B60, Pyr, G/S, C30" /AntisenseName="yppG" /AntisenseCor="0.96504903995490698" /AntisenseRegPval="-156.6" /CDS_PredictionProba="NA" /TUshortSig="NA" /TUshortPSig="NA" /TUlongSig="NA" /TUlongPSig="NA" /label="S842" promotor_-10 complement(2204022..2204040) /Source="Nicolas_upshift_promotors" /id="U1747" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1321 /SigmaFactorBS="aactttcgacacaatttgacaaatgctaatcatcacttGTGA CACAAAcaatagaagtcatTCATACATATATAGAAGAGaaatatgttgtgtttagggg g" /listShort="yppG" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2204041) /Source="Nicolas_upshifts" /id="U1747" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1321 /SigmaFactorBS="aactttcgacacaatttgacaaatgctaatcatcacttGTGA CACAAAcaatagaagtcatTCATACATATATAGAAGAGaaatatgttgtgtttagggg g" /listShort="yppG" /GFF_Attribute="listLong" promotor_-35 complement(2204054..2204063) /Source="Nicolas_upshift_promotors" /id="U1747" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1321 /SigmaFactorBS="aactttcgacacaatttgacaaatgctaatcatcacttGTGA CACAAAcaatagaagtcatTCATACATATATAGAAGAGaaatatgttgtgtttagggg g" /listShort="yppG" /GFF_Attribute="listLong" /label="promotor_-35" misc_feature 2204136..2204155 /Source="Nicolas_upshift_promotors" /id="U1748" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.896103896103896" /psig="0.994005994005994" /xcortree=2721 /SigmaFactorBS="catttgtcaaattgtgtcgaaagtttaaattttttaaaaaca gaaaaaagtcgaatcatTATGGTACCATATTTTCAATacagatgagaggggatgcacc a" /listShort="yppF" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 2204137 /Source="Nicolas_upshifts" /id="U1748" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.896103896103896" /psig="0.994005994005994" /xcortree=2721 /SigmaFactorBS="catttgtcaaattgtgtcgaaagtttaaattttttaaaaaca gaaaaaagtcgaatcatTATGGTACCATATTTTCAATacagatgagaggggatgcacc a" /listShort="yppF" /GFF_Attribute="listLong" CDS 2204180..2204368 /gene="yppF" /locus_tag="BSU_22260" /old_locus_tag="BSU22260" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 22720735, 22882546; Product type f: factor" /codon_start=1 /transl_table=11 /product="putative sporulation protein" /protein_id="NP_390108.1" /db_xref="EnsemblGenomes-Gn:BSU22260" /db_xref="EnsemblGenomes-Tr:CAB14143" /db_xref="InterPro:IPR025553" /db_xref="SubtiList:BG11447" /db_xref="UniProtKB/Swiss-Prot:P50834" /translation="MNVSYLSKRFAEMKKYETDCMNKLMDFAKFLYIQGHLSITEFRN SMKVLEANGAESPAYEMN*" gene 2204180..2204368 /gene="yppF" /locus_tag="BSU_22260" /old_locus_tag="BSU22260" downshifts 2204384 /Source="Nicolas_upshifts" /id="D1168" /incds=0 /nref=112 /ntot=242 /MaxReadThrough="3.3677" /MaxDrop="5.69944" /score="0.283992322" /energy="-8.5" /TU="U1748" /idTUdmin="U1748" /TUdmin="-200" /isTUend="FALSE" CDS complement(2204407..2204778) /gene="yppE" /locus_tag="BSU_22270" /old_locus_tag="BSU22270" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_390109.1" /db_xref="EnsemblGenomes-Gn:BSU22270" /db_xref="EnsemblGenomes-Tr:CAB14144" /db_xref="InterPro:IPR014913" /db_xref="InterPro:IPR023351" /db_xref="PDB:2HFI" /db_xref="PDB:2IM8" /db_xref="SubtiList:BG11446" /db_xref="UniProtKB/Swiss-Prot:P50833" /translation="MLSQTLLEMTEQMIEVAEKGADRYQEGKNSNHSYDFFETIKPAV EENDELAARWAEGALELIKVRRPKYVHKEQIEAVKDNFLELVLQSYVHHIHKKRFKDI TESVLYTLHAVKDEIAREDSR*" gene complement(2204407..2204778) /gene="yppE" /locus_tag="BSU_22270" /old_locus_tag="BSU22270" downshifts complement(2204440) /Source="Nicolas_upshifts" /id="D1169" /incds=0 /nref=158 /ntot=245 /MaxReadThrough="1.04225" /MaxDrop="5.78413" /score="-2.77698308" /energy="-10.3" /TU="NA" /idTUdmin="U1749" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(2204790..2204809) /Source="Nicolas_upshift_promotors" /id="U1749" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.943056943056943" /psig=1 /xcortree=2155 /SigmaFactorBS="acacaggtatgcgtttgagaaggtataccgcatcggCTGAAT ttgtgagtgaaaTTTGGTACGATAGGCATTGAggtgaaagatattgctatcacaaact t" /listShort="yppE" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2204803) /Source="Nicolas_upshifts" /id="U1749" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.943056943056943" /psig=1 /xcortree=2155 /SigmaFactorBS="acacaggtatgcgtttgagaaggtataccgcatcggCTGAAT ttgtgagtgaaaTTTGGTACGATAGGCATTGAggtgaaagatattgctatcacaaact t" /listShort="yppE" /GFF_Attribute="listLong" promotor_-35 complement(2204822..2204827) /Source="Nicolas_upshift_promotors" /id="U1749" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.943056943056943" /psig=1 /xcortree=2155 /SigmaFactorBS="acacaggtatgcgtttgagaaggtataccgcatcggCTGAAT ttgtgagtgaaaTTTGGTACGATAGGCATTGAggtgaaagatattgctatcacaaact t" /listShort="yppE" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2204824..2205069) /gene="yppD" /locus_tag="BSU_22280" /old_locus_tag="BSU22280" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15687200; Product type f: factor" /codon_start=1 /transl_table=11 /product="putative sporulation protein" /protein_id="NP_390110.1" /db_xref="EnsemblGenomes-Gn:BSU22280" /db_xref="EnsemblGenomes-Tr:CAB14145" /db_xref="InterPro:IPR020252" /db_xref="SubtiList:BG11445" /db_xref="UniProtKB/Swiss-Prot:P50832" /translation="MSGYVCKTDILRMLSDIEDELTRAEQSLNHSVNALEAEMRETEN DRLSVLEEEIIDLHICINELYQSPEHRYAFEKVYRIG*" gene complement(2204824..2205069) /gene="yppD" /locus_tag="BSU_22280" /old_locus_tag="BSU22280" promotor_-10 complement(2205095..2205113) /Source="Nicolas_upshift_promotors" /id="U1750" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp=1 /psig=1 /xcortree=446 /SigmaFactorBS="gcgatttgcttctagttttgtcatgagGAAGGAAAGagcctt gagagCAAAGAATGTTAACCGGGAgagacaaggaaagggaggtacacgaatgtccggt t" /listShort="yppD, yppE" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2205100) /Source="Nicolas_upshifts" /id="U1750" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp=1 /psig=1 /xcortree=446 /SigmaFactorBS="gcgatttgcttctagttttgtcatgagGAAGGAAAGagcctt gagagCAAAGAATGTTAACCGGGAgagacaaggaaagggaggtacacgaatgtccggt t" /listShort="yppD, yppE" /GFF_Attribute="listLong" promotor_-35 complement(2205125..2205133) /Source="Nicolas_upshift_promotors" /id="U1750" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp=1 /psig=1 /xcortree=446 /SigmaFactorBS="gcgatttgcttctagttttgtcatgagGAAGGAAAGagcctt gagagCAAAGAATGTTAACCGGGAgagacaaggaaagggaggtacacgaatgtccggt t" /listShort="yppD, yppE" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 2205219..2205225 /Source="Nicolas_upshift_promotors" /id="U1751" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=860 /SigmaFactorBS="ctgaagttttcgacaaaaacacccgcaaaaatTGTATGAtcc tcctcattaatGCAAACGATACTtgtgaggaggtgccgtatgaaaacaagaccgaaaa a" /listShort="sspM" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2205240..2205251 /Source="Nicolas_upshift_promotors" /id="U1751" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=860 /SigmaFactorBS="ctgaagttttcgacaaaaacacccgcaaaaatTGTATGAtcc tcctcattaatGCAAACGATACTtgtgaggaggtgccgtatgaaaacaagaccgaaaa a" /listShort="sspM" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2205247 /Source="Nicolas_upshifts" /id="U1751" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=860 /SigmaFactorBS="ctgaagttttcgacaaaaacacccgcaaaaatTGTATGAtcc tcctcattaatGCAAACGATACTtgtgaggaggtgccgtatgaaaacaagaccgaaaa a" /listShort="sspM" /GFF_Attribute="listLong" CDS 2205268..2205372 /gene="sspM" /locus_tag="BSU_22290" /old_locus_tag="BSU22290" /function="16.5: Explore" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:10806362" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10806362; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="small acid-soluble spore protein" /protein_id="YP_054585.1" /db_xref="EnsemblGenomes-Gn:BSU22290" /db_xref="EnsemblGenomes-Tr:CAE01459" /db_xref="GOA:Q7WY65" /db_xref="SubtiList:BG14177" /db_xref="UniProtKB/Swiss-Prot:Q7WY65" /translation="MKTRPKKAGQQKKTESKAIDSLDKKLGGPNRPST*" gene 2205268..2205372 /gene="sspM" /locus_tag="BSU_22290" /old_locus_tag="BSU22290" downshifts 2205354 /Source="Nicolas_upshifts" /id="D1170" /incds=0 /nref=31 /ntot=49 /MaxReadThrough="1.6498" /MaxDrop="6.01285" /score="0.283992322" /energy="-8.5" /TU="NA" /idTUdmin="U1751" /TUdmin=0 /isTUend="TRUE" CDS complement(2205397..2206359) /gene="yppC" /locus_tag="BSU_22300" /old_locus_tag="BSU22300" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_390111.1" /db_xref="EnsemblGenomes-Gn:BSU22300" /db_xref="EnsemblGenomes-Tr:CAB14146" /db_xref="InterPro:IPR019658" /db_xref="SubtiList:BG10952" /db_xref="UniProtKB/Swiss-Prot:P39791" /translation="MNVQEQQAIRKLLSRIERQTKMKNADNISRTNAYKAFYDRHPEI KWSLLASFVSRNAGWSMTDLKGSLFQLGLRERQQKWFFLAYERANWLIFSDAYPQLLL YHWSKRVGKPLFHLLHVFGVSQFMSEEWTRFWHERNTERLMYALIINEQNTIQTPIIQ NPSFKKNVFDTIPFYLSDWFHFNTVIFPSSNGFFYGISVKRFSKAEERIRLGKQLSQL LFKPELFSSFYHFLHTVPHTGSRFDMEKMIGITKRTSPMLRTCYPELIHSLDGTKTDW FHGKIKKTFFRREELPKQIELTDWYLHKKRQLHALFAVEQWLKK*" gene complement(2205397..2206359) /gene="yppC" /locus_tag="BSU_22300" /old_locus_tag="BSU22300" promotor_-35 2205527..2205536 /Source="Nicolas_upshift_promotors" /id="U1752" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1658 /SigmaFactorBS="aattcctcgcgcctaaagaacgttttctttatctttccaTGA AACCAATctgttttcgttCCGTCTAATGAGTGGAttaactcagggtagcatgtcctta g" /listShort="S843, S844, recU, ponA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2205548..2205563 /Source="Nicolas_upshift_promotors" /id="U1752" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1658 /SigmaFactorBS="aattcctcgcgcctaaagaacgttttctttatctttccaTGA AACCAATctgttttcgttCCGTCTAATGAGTGGAttaactcagggtagcatgtcctta g" /listShort="S843, S844, recU, ponA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2205548 /Source="Nicolas_upshifts" /id="U1752" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1658 /SigmaFactorBS="aattcctcgcgcctaaagaacgttttctttatctttccaTGA AACCAATctgttttcgttCCGTCTAATGAGTGGAttaactcagggtagcatgtcctta g" /listShort="S843, S844, recU, ponA" /GFF_Attribute="listLong" S_feature 2205552..2205887 /Source="Nicolas_S_feature" /locus_tag="new_2339954_2340289" /HighExp="T1.0H, T0.30H, T1.30H, H2O2, Paraq, LBGstat, T2.0H, T-0.40H, Salt, T2.30H" /AntisenseName="yppC" /AntisenseCor="-0.27690969451148201" /AntisenseRegPval="-5.4" /CDS_PredictionProba="NA" /TUshortSig="SigWXY" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S843" promotor_-35 2205858..2205862 /Source="Nicolas_upshift_promotors" /id="U1753" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.965034965034965" /psig=1 /xcortree=2511 /SigmaFactorBS="acttaaataaaaaggaatcgtgtcaaaaaCATTCtttttaaa cgaaggaTTTTGTATAATAGGTGTTTGgatagtgttttgttcatttataatgagggca t" /listShort="S844, recU, ponA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2205878..2205897 /Source="Nicolas_upshift_promotors" /id="U1753" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.965034965034965" /psig=1 /xcortree=2511 /SigmaFactorBS="acttaaataaaaaggaatcgtgtcaaaaaCATTCtttttaaa cgaaggaTTTTGTATAATAGGTGTTTGgatagtgttttgttcatttataatgagggca t" /listShort="S844, recU, ponA" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 2205889..2206399 /Source="Nicolas_S_feature" /locus_tag="new_2340291_2340801" /HighExp="LBGstat, T1.0H, T1.30H, H2O2, T0.30H, Paraq, T2.0H, C30, G135, G180" /AntisenseName="yppC" /AntisenseCor="-0.312791370178301" /AntisenseRegPval="-6.8" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigWXY" /TUshortPSig="1, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S844" upshifts 2205889 /Source="Nicolas_upshifts" /id="U1753" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.965034965034965" /psig=1 /xcortree=2511 /SigmaFactorBS="acttaaataaaaaggaatcgtgtcaaaaaCATTCtttttaaa cgaaggaTTTTGTATAATAGGTGTTTGgatagtgttttgttcatttataatgagggca t" /listShort="S844, recU, ponA" /GFF_Attribute="listLong" S_feature complement(2206360..2206816) /Source="Nicolas_S_feature" /locus_tag="new_2340762_2341218_c" /HighExp="S8, S6, S7, S5, C30, G135, S4, BT, G180, Fru" /AntisenseName="recU" /AntisenseCor="-0.34780203121991599" /AntisenseRegPval="-8.3000000000000007" /CDS_PredictionProba="NA" /TUshortSig="SigGF" /TUshortPSig="0.997" /TUlongSig="NA" /TUlongPSig="NA" /label="S845" CDS 2206400..2207020 /gene="recU" /locus_tag="BSU_22310" /old_locus_tag="BSU22310" /function="16.6: Maintain" /function="16.9: Replicate" /experiment="publication(s) with functional evidences, PMID:14701911, 15317759, 16020779, 16024744, 19433509, 19542287, 20735784, 21600217, 27903910" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 14701911, 15317759, 16020779, 16024744, 19433509, 19542287, 20735784, 21600217, 27903910; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="Holliday junction resolvase" /protein_id="NP_390112.1" /db_xref="EnsemblGenomes-Gn:BSU22310" /db_xref="EnsemblGenomes-Tr:CAB14147" /db_xref="GOA:P39792" /db_xref="InterPro:IPR004612" /db_xref="InterPro:IPR011335" /db_xref="PDB:1RZN" /db_xref="PDB:1ZP7" /db_xref="PDB:5FDK" /db_xref="SubtiList:BG10953" /db_xref="UniProtKB/Swiss-Prot:P39792" /translation="MIRYPNGKTFQPKHSVSSQNSQKRAPSYSNRGMTLEDDLNETNK YYLTNQIAVIHKKPTPVQIVNVHYPKRSAAVIKEAYFKQSSTTDYNGIYKGRYIDFEA KETKNKTSFPLQNFHDHQIEHMKQVKAQDGICFVIISAFDQVYFLEADKLFYFWDRKE KNGRKSIRKDELEETAYPISLGYAPRIDYISIIEQLYFSPSSGAKG*" gene 2206400..2207020 /gene="recU" /locus_tag="BSU_22310" /old_locus_tag="BSU22310" promotor_-10 complement(2206805..2206816) /Source="Nicolas_upshift_promotors" /id="U1754" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=893 /SigmaFactorBS="ttttctgtcccagaaataaaacagcttatcggcttccaaAAA ATAAacctggtcgaaagcGGATATAATAACaaaacaaataccgtcttgagcctttacc t" /listShort="S845" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2206816) /Source="Nicolas_upshifts" /id="U1754" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=893 /SigmaFactorBS="ttttctgtcccagaaataaaacagcttatcggcttccaaAAA ATAAacctggtcgaaagcGGATATAATAACaaaacaaataccgtcttgagcctttacc t" /listShort="S845" /GFF_Attribute="listLong" promotor_-35 complement(2206831..2206837) /Source="Nicolas_upshift_promotors" /id="U1754" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=893 /SigmaFactorBS="ttttctgtcccagaaataaaacagcttatcggcttccaaAAA ATAAacctggtcgaaagcGGATATAATAACaaaacaaataccgtcttgagcctttacc t" /listShort="S845" /GFF_Attribute="listLong" /label="promotor_-35" CDS 2207042..2209786 /gene="ponA" /locus_tag="BSU_22320" /old_locus_tag="BSU22320" /EC_number="2.4.1.129" /function="16.9: Replicate" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:10322023, 10692371, 12562814, 15262952, 18266856, 25355936, 27852437" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10322023, 10692371, 12562814, 15262952, 18266856, 25355936, 27852437; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="peptidoglycan glycosyltransferase (penicillin-binding proteins 1A and 1B)" /protein_id="NP_390113.1" /db_xref="EnsemblGenomes-Gn:BSU22320" /db_xref="EnsemblGenomes-Tr:CAB14148" /db_xref="GOA:P39793" /db_xref="InterPro:IPR001264" /db_xref="InterPro:IPR001460" /db_xref="InterPro:IPR003961" /db_xref="InterPro:IPR012338" /db_xref="InterPro:IPR013783" /db_xref="InterPro:IPR023346" /db_xref="InterPro:IPR036116" /db_xref="InterPro:IPR036950" /db_xref="SubtiList:BG10954" /db_xref="UniProtKB/Swiss-Prot:P39793" /translation="MSDQFNSREARRKANSKSSPSPKKGKKRKKGGLFKKTLFTLLIL FVLGVVGGAVTFAVMVSDAPSLDESKLKTPYSSTIYDKNGKEIAEVGAEKRTYVSIDE IPDVVKEAFIATEDARFYEHHGIDPVRIGGALVANFKDGFGAEGGSTITQQVVKNSLL SHQKTLKRKVQEVWLSIQLERNYSKDEILEMYLNRIYFSPRAYGIGKAAEEFFGVTDL SKLTVEQAATLAGMPQSPTAYNPVKNPDKAEKRRNIVLSLMKKQGFISDSQYNKAKKV AVKDEGVVSQKEYEKASTNKYSAFVEEVMKEIDEKSDVDPSADGLKIYTTLDTKAQDK LDELMDGDTVGFTEGMQGGVTLLDTKNGEVRAIGAGRNQPVGGFNYATQTKAQPGSTI KPILDYGPVIENKKWSTYEQIDDSAYTYSNGKPIRDWDRKYLGPISMRYALAQSRNIP ALKAFQAVGKDTAVDFANGLGLGLTKDNVTEAYSIGGFGGNDGVSPLTMAGAYSAFGN NGTYNEPHFVKSIEFNDGTKLDLTPKSKSAMSDYTAFMITDMLKTAVKTGTGQLAQVP GVEVAGKTGTTNFDDNEVKRYNIASGGARDSWFVGYTPQYTAAVWTGMGENEAGKKSL SAEEQKVAKRIFAQLIADVDDGSGSFEKPDSVVEATVEKGSNPAKLAGPNTPSDKKLT EYFVKGTAPSTVSKTYEKEEKEETAKLSGLNVKYDKDNQSLTLSWNYDGDATFAVKQS VDGGSYSEIQNSSAKEAVISGVQPGSVYKFEVTAVSDDGKSTASTSYEVPKAEDDEDK KDQQQTDDEKQDDEKTQDDTQTDDSQKDDGQTDQDQTDDSTNDQDKKQDNTNTNPSDN NNQDQSNDNDNDNSNNQDTSDGDSNSGKNDSTGSDTNKNKTDTSNKTQTNSSSIEKTN *" gene 2207042..2209786 /gene="ponA" /locus_tag="BSU_22320" /old_locus_tag="BSU22320" downshifts complement(2209456) /Source="Nicolas_upshifts" /id="D1171" /incds=1 /nref=1 /ntot=77 /MaxReadThrough="1.95969" /MaxDrop="2.87717" /score="24.9960782" /energy="-11.3" /TU="NA" /idTUdmin="U1755" /TUdmin=418 /isTUend="FALSE" downshifts 2209772 /Source="Nicolas_upshifts" /id="D1172" /incds=0 /nref=243 /ntot=302 /MaxReadThrough="1.61976" /MaxDrop="7.42523" /score="24.2831363" /energy="-14.6" /TU="U1753" /idTUdmin="U1752" /TUdmin="-4" /isTUend="TRUE" CDS complement(2209862..2210356) /gene="ypoC" /locus_tag="BSU_22330" /old_locus_tag="BSU22330" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_390114.1" /db_xref="EnsemblGenomes-Gn:BSU22330" /db_xref="EnsemblGenomes-Tr:CAB14149" /db_xref="SubtiList:BG10955" /db_xref="UniProtKB/Swiss-Prot:P39789" /translation="MTQAKEVLASYEQYLRSLGQKSSSDMKKTLQTNPVYFDFCTELQ GDLPWEDSGKYVPLLFEVWDDIKASLLPVFQTRKSRCDQNEMLKGIVCLLASLHWTAG EPVKSLDWQELREKSYPAKPINWAERVEFILLKPTQYHCFIQLDELITEMKKHFYKYH AMNR*" gene complement(2209862..2210356) /gene="ypoC" /locus_tag="BSU_22330" /old_locus_tag="BSU22330" downshifts complement(2209875) /Source="Nicolas_upshifts" /id="D1173" /incds=0 /nref=116 /ntot=222 /MaxReadThrough="2.50883" /MaxDrop="5.43593" /score="29.5358766" /energy="-11.6" /TU="NA" /idTUdmin="U1755" /TUdmin="-1" /isTUend="TRUE" CDS complement(2210353..2211012) /gene="nth" /locus_tag="BSU_22340" /old_locus_tag="BSU22340" /EC_number="4.2.99.18" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:9808040, 11160880, 12682299, 21954439, 24914186" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9808040, 11160880, 12682299, 21954439, 24914186; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="endonuclease III, apurinic apyrimidic DNA lyase" /protein_id="NP_390115.1" /db_xref="EnsemblGenomes-Gn:BSU22340" /db_xref="EnsemblGenomes-Tr:CAB14150" /db_xref="GOA:P39788" /db_xref="InterPro:IPR000445" /db_xref="InterPro:IPR003265" /db_xref="InterPro:IPR003651" /db_xref="InterPro:IPR004035" /db_xref="InterPro:IPR004036" /db_xref="InterPro:IPR005759" /db_xref="InterPro:IPR011257" /db_xref="InterPro:IPR023170" /db_xref="SubtiList:BG10956" /db_xref="UniProtKB/Swiss-Prot:P39788" /translation="MLNLKQIEFCLDKIGDMFPHAECELVHSNPFELVVAVALSAQCT DALVNRVTKTLFQKYKRPEDYLAVPLEELQQDIKSIGLYRNKAKNIQKLSKMIIEDYG GEVPRDRDELVKLPGVGRKTANVVVSVAFGVPAIAVDTHVERVSKRLGICRWKDSVLE VEKTLMRKVPKEDWSVTHHRLIFFGRYHCKAQSPRCAECPLLSLCREGQKRDKKGLVK R*" gene complement(2210353..2211012) /gene="nth" /locus_tag="BSU_22340" /old_locus_tag="BSU22340" CDS complement(2211031..2211729) /gene="dnaD" /locus_tag="BSU_22350" /old_locus_tag="BSU22350" /function="16.9: Replicate" /function="16.6: Maintain" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:11222620, 12682299, 15556628, 15686560, 16002087, 16677303, 16855238, 17277452, 18206906, 21954439, 22821970, 23909787" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11222620, 12682299, 15556628, 15686560, 16002087, 16677303, 16855238, 17277452, 18206906, 21954439, 22821970, 23909787; Product type f: factor" /codon_start=1 /transl_table=11 /product="DNA-remodelling primosomal protein" /protein_id="NP_390116.1" /db_xref="EnsemblGenomes-Gn:BSU22350" /db_xref="EnsemblGenomes-Tr:CAB14151" /db_xref="GOA:P39787" /db_xref="InterPro:IPR006343" /db_xref="InterPro:IPR034829" /db_xref="PDB:2V79" /db_xref="SubtiList:BG10957" /db_xref="UniProtKB/Swiss-Prot:P39787" /translation="MKKQQFIDMQEQGTSTIPNLLLTHYKQLGLNETELILLLKIKMH LEKGSYFPTPNQLQEGMSISVEECTNRLRMFIQKGFLFIEECEDQNGIKFEKYSLQPL WGKLYEYIQLAQNQTQERKAEGEQKSLYTIFEEEFARPLSPLECETLAIWQDQDQHDA QLIKHALKEAVLSGKLSFRYIDRILFEWKKNGLKTVEQAKIHSQKFRRVQAKQNEPQK EYKRQVPFYNWLEQ*" gene complement(2211031..2211729) /gene="dnaD" /locus_tag="BSU_22350" /old_locus_tag="BSU22350" S_feature complement(2211730..2211821) /Source="Nicolas_S_feature" /locus_tag="new_2346132_2346223_c" /HighExp="LoTm, G180, Cold, G135, LBGstat, G150, C30, Etha, Oxctl, M9-stat" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA, SigA, SigA" /TUshortPSig="0.999, 0.994, 0.85, 1" /TUlongSig="SigWXY, SigA, SigA" /TUlongPSig="1, 1, 0.995" /label="S846" CDS complement(2211822..2213114) /gene="asnS" /locus_tag="BSU_22360" /old_locus_tag="BSU22360" /EC_number="6.1.1.22" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 12682299, 26804570; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="asparaginyl-tRNA synthetase" /protein_id="NP_390117.1" /db_xref="EnsemblGenomes-Gn:BSU22360" /db_xref="EnsemblGenomes-Tr:CAB14152" /db_xref="GOA:P39772" /db_xref="InterPro:IPR002312" /db_xref="InterPro:IPR004364" /db_xref="InterPro:IPR004365" /db_xref="InterPro:IPR004522" /db_xref="InterPro:IPR006195" /db_xref="InterPro:IPR012340" /db_xref="SubtiList:BG10958" /db_xref="UniProtKB/Swiss-Prot:P39772" /translation="MKTTINQVYKHVGEEVTIGAWVANKRSSGKIAFLQLRDGTGFIQ GVVVKAEVEESIFQTAKSVTQETSLYIKGIVKEDERSPLGYELAVTDIEVIHEATDYP ITPKEHGTEFLMDHRHLWLRSKRQHAIMKIRNEIIRATYEFFNNEGFVKVDPPILTGS APEGTTELFATKYFDEDAYLSQSGQLYMEAAAMALGKVFSFGPTFRAEKSKTKRHLIE FWMIEPEMAFVEFEENLQVQENYVSFIVQSVLKNCKIELNTLGRDTSKLEQIKAPFPR ITYDEAIEFLKEKGFDDIEWGDDFGAPHETAIAEHYDKPVFITRYPTSLKPFYMQPAS DREDVVLCADLIAPEGYGEIIGGSERIHDMELLESRLKEHGLDSDAYKWYAELRKYGS VPHSGFGLGLERTVAWISGAPHVRETIPFPRLLNRLYP*" gene complement(2211822..2213114) /gene="asnS" /locus_tag="BSU_22360" /old_locus_tag="BSU22360" S_feature complement(2213115..2213176) /Source="Nicolas_S_feature" /locus_tag="new_2347517_2347578_c" /HighExp="LBGexp, dia0, Lbexp, G150, G180, LPh, C30, Oxctl, LBGtran, G135" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA, SigA, SigA" /TUshortPSig="0.999, 0.994, 0.85, 1" /TUlongSig="SigWXY, SigA, SigA" /TUlongPSig="1, 1, 0.995" /label="S847" promotor_-10 complement(2213176..2213195) /Source="Nicolas_upshift_promotors" /id="U1755" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.663336663336663" /psig="0.999000999001" /xcortree=2680 /SigmaFactorBS="gaaaagccgctttttatctGCATTGACccggttagttaagaG CGGGTATAATAAAGTGATGataaaagagttcgcggggcaatgagcttccgaatgtctt t" /listShort="S847, asnS, S846, dnaD, nth, ypoC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2213176) /Source="Nicolas_upshifts" /id="U1755" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.663336663336663" /psig="0.999000999001" /xcortree=2680 /SigmaFactorBS="gaaaagccgctttttatctGCATTGACccggttagttaagaG CGGGTATAATAAAGTGATGataaaagagttcgcggggcaatgagcttccgaatgtctt t" /listShort="S847, asnS, S846, dnaD, nth, ypoC" /GFF_Attribute="listLong" promotor_-35 complement(2213210..2213217) /Source="Nicolas_upshift_promotors" /id="U1755" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.663336663336663" /psig="0.999000999001" /xcortree=2680 /SigmaFactorBS="gaaaagccgctttttatctGCATTGACccggttagttaagaG CGGGTATAATAAAGTGATGataaaagagttcgcggggcaatgagcttccgaatgtctt t" /listShort="S847, asnS, S846, dnaD, nth, ypoC" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2213258..2214439) /gene="aspB" /locus_tag="BSU_22370" /old_locus_tag="BSU22370" /EC_number="2.6.1.1" /function="16.11: Scavenge (Catabolism)" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:418816, 12670965, 22740702" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 418816, 12670965, 22740702; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="anabolic oxaloacetate / glutamate aminotransferase" /protein_id="NP_390118.1" /db_xref="EnsemblGenomes-Gn:BSU22370" /db_xref="EnsemblGenomes-Tr:CAB14153" /db_xref="GOA:P53001" /db_xref="InterPro:IPR004838" /db_xref="InterPro:IPR004839" /db_xref="InterPro:IPR015421" /db_xref="InterPro:IPR015422" /db_xref="InterPro:IPR015424" /db_xref="SubtiList:BG11513" /db_xref="UniProtKB/Swiss-Prot:P53001" /translation="MKLAKRVSALTPSTTLAITAKAKELKAAGHDVIGLGAGEPDFNT PQHIIDAAVRSMNEGHTKYTPSGGLAELKNSIAEKFKRDQNIEYKPSQIIVCTGAKHA LYTLFQVILDEEDEVIIPTPYWVSYPEQVKLAGGKPVYVEGLEENHFKISPEQLKNAI TEKTKAIVINSPSNPTGVMYTEEELSALGEVCLEHDILIVSDEIYEKLTYGGKKHVSI AQLSDRLKEQTVIINGVSKSHSMTGWRIGYAAGSEDIIKAMTNLASHSTSNPTSIAQY GAIAAYNGPSEPLEEMREAFEHRLNTIYAKLIEIPGFSCVKPEGAFYLFPNAKEAAQS CGFKDVDEFVKALLEEEKVAIVPGSGFGSPENVRLSYATSLDLLEEAIERIKRFVEKH S*" gene complement(2213258..2214439) /gene="aspB" /locus_tag="BSU_22370" /old_locus_tag="BSU22370" downshifts complement(2213262) /Source="Nicolas_upshifts" /id="D1174" /incds=0 /nref=48 /ntot=196 /MaxReadThrough="6.37268" /MaxDrop="4.0831" /score="5.04709675" /energy="-9.3" /TU="U1756,U1758,U1760,U1761,U1762" /idTUdmin="U1760" /TUdmin="-66" /isTUend="FALSE" CDS complement(2214462..2214947) /gene="tseB" /locus_tag="BSU_22380" /old_locus_tag="BSU22380" /experiment="publication(s) with functional evidences, PMID:25954268" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 25954268; Product type ph: phenotype" /codon_start=1 /transl_table=11 /product="suppressor of tetracyclin sensitivity of an ezrAmutant" /protein_id="NP_390119.1" /db_xref="EnsemblGenomes-Gn:BSU22380" /db_xref="EnsemblGenomes-Tr:CAB14154" /db_xref="GOA:P54396" /db_xref="InterPro:IPR025711" /db_xref="PDB:2GU3" /db_xref="SubtiList:BG11502" /db_xref="UniProtKB/Swiss-Prot:P54396" /translation="MRKKALIFTVIFGIIFLAVLLVSASIYKSAMAQKEEGHEAAAAE AKKETDLAHVDQVETFVGKEKYYVVKGTDKKGTALYVWVPADKKAKILSKEAKEGISE DKAAKIIKDEGLVSKQKEVHLAREGNVLLWEVTYLDKEGQYSLSYVDFTTGKILKNIT P*" gene complement(2214462..2214947) /gene="tseB" /locus_tag="BSU_22380" /old_locus_tag="BSU22380" promotor_-10 complement(2214895..2214914) /Source="Nicolas_upshift_promotors" /id="U1756" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.47952047952048" /psig="0.994005994005994" /xcortree=2324 /SigmaFactorBS="ccatttatcgtacgtaggtgagaagatgagaaaaaaagCATT AATAtttaccgtcattTTTGGTATTATTTTTTTAGCagtacttcttgtctcggcaagc a" /listShort="ypmB, aspB, S847, asnS, S846, dnaD, nth, ypoC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2214912) /Source="Nicolas_upshifts" /id="U1756" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.47952047952048" /psig="0.994005994005994" /xcortree=2324 /SigmaFactorBS="ccatttatcgtacgtaggtgagaagatgagaaaaaaagCATT AATAtttaccgtcattTTTGGTATTATTTTTTTAGCagtacttcttgtctcggcaagc a" /listShort="ypmB, aspB, S847, asnS, S846, dnaD, nth, ypoC" /GFF_Attribute="listLong" promotor_-35 complement(2214927..2214934) /Source="Nicolas_upshift_promotors" /id="U1756" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.47952047952048" /psig="0.994005994005994" /xcortree=2324 /SigmaFactorBS="ccatttatcgtacgtaggtgagaagatgagaaaaaaagCATT AATAtttaccgtcattTTTGGTATTATTTTTTTAGCagtacttcttgtctcggcaagc a" /listShort="ypmB, aspB, S847, asnS, S846, dnaD, nth, ypoC" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2214956..2215126) /gene="ypmA" /locus_tag="BSU_22390" /old_locus_tag="BSU22390" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 22720735" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_390120.1" /db_xref="EnsemblGenomes-Gn:BSU22390" /db_xref="EnsemblGenomes-Tr:CAB14155" /db_xref="InterPro:IPR012190" /db_xref="SubtiList:BG11501" /db_xref="UniProtKB/Swiss-Prot:P54395" /translation="MESKIEILSTINVEHSDDLYKIVDTLNRTLKRDNLMFGLALDEE NKNQAVFTIYRT*" gene complement(2214956..2215126) /gene="ypmA" /locus_tag="BSU_22390" /old_locus_tag="BSU22390" S_feature complement(2215127..2215198) /Source="Nicolas_S_feature" /locus_tag="new_2349529_2349600_c" /HighExp="H2O2, T0.30H, T0.0H, dia15, T-0.40H, T-1.10H, G135, T1.0H, G180, Paraq" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.136042" /TUshortSig="SigA, SigWXY, SigA, SigA, SigA" /TUshortPSig="0.85, 1, 1, 1, 0.995" /TUlongSig="NA" /TUlongPSig="NA" /label="S848" promotor_-35 2215160..2215166 /Source="Nicolas_upshift_promotors" /id="U1757" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=823 /SigmaFactorBS="ttttcatcctccagtttgaacaaatattgttaGTCATACtcc atttcaggacaCGCCATACTAGTatcacagagcgggaaatccgcttttaaataaaaca c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(2215181..2215200) /Source="Nicolas_upshift_promotors" /id="U1758" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.646353646353646" /psig="0.85014985014985" /xcortree=1587 /SigmaFactorBS="aagcggcttttgcggtgtgggagtaggatggtgtttTATTTA AaagcggatttcccgcTCTGTGATACTAGTATGGCGtgtcctgaaatggagtatgact a" /listShort="S848, ypmA, ypmB, aspB, S847, asnS, S846, dnaD, nth, ypoC" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-10 2215181..2215192 /Source="Nicolas_upshift_promotors" /id="U1757" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=823 /SigmaFactorBS="ttttcatcctccagtttgaacaaatattgttaGTCATACtcc atttcaggacaCGCCATACTAGTatcacagagcgggaaatccgcttttaaataaaaca c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 2215188..2215262 /Source="Nicolas_S_feature" /locus_tag="new_2349590_2349664" /HighExp="S8, S6, S5, S7, nit, BT, G/S, Pyr, C30, ferm" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="NA" /TUshortPSig="NA" /TUlongSig="NA" /TUlongPSig="NA" /label="S849" upshifts 2215188 /Source="Nicolas_upshifts" /id="U1757" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=823 /SigmaFactorBS="ttttcatcctccagtttgaacaaatattgttaGTCATACtcc atttcaggacaCGCCATACTAGTatcacagagcgggaaatccgcttttaaataaaaca c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" upshifts complement(2215198) /Source="Nicolas_upshifts" /id="U1758" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.646353646353646" /psig="0.85014985014985" /xcortree=1587 /SigmaFactorBS="aagcggcttttgcggtgtgggagtaggatggtgtttTATTTA AaagcggatttcccgcTCTGTGATACTAGTATGGCGtgtcctgaaatggagtatgact a" /listShort="S848, ypmA, ypmB, aspB, S847, asnS, S846, dnaD, nth, ypoC" /GFF_Attribute="listLong" S_feature complement(2215200..2215268) /Source="Nicolas_S_feature" /locus_tag="new_2349602_2349670_c" /HighExp="T0.30H, T1.0H, T-0.40H, T1.30H, T0.0H, Salt, H2O2, T-1.10H, Oxctl, G150" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigWXY, SigA, SigA, SigA" /TUshortPSig="1, 1, 1, 0.995" /TUlongSig="NA" /TUlongPSig="NA" /label="S850" promotor_-35 complement(2215216..2215222) /Source="Nicolas_upshift_promotors" /id="U1758" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.646353646353646" /psig="0.85014985014985" /xcortree=1587 /SigmaFactorBS="aagcggcttttgcggtgtgggagtaggatggtgtttTATTTA AaagcggatttcccgcTCTGTGATACTAGTATGGCGtgtcctgaaatggagtatgact a" /listShort="S848, ypmA, ypmB, aspB, S847, asnS, S846, dnaD, nth, ypoC" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 2215232 /Source="Nicolas_upshifts" /id="D1175" /incds=0 /nref=8 /ntot=26 /MaxReadThrough="0.48859" /MaxDrop="6.02806" /score="18.4569945" /energy="-8.4" /TU="NA" /idTUdmin="U1757" /TUdmin=0 /isTUend="TRUE" CDS complement(2215269..2218064) /gene="dinG" /locus_tag="BSU_22400" /old_locus_tag="BSU22400" /EC_number="3.6.1.-" /function="16.6: Maintain" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:8385320, 12060778, 17416902, 21546913, 22166102, 28527403" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8385320, 12060778, 17416902, 21546913, 22166102, 28527403; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="damage inducible ATP-dependent 3'->5' nuclease" /protein_id="NP_390121.1" /db_xref="EnsemblGenomes-Gn:BSU22400" /db_xref="EnsemblGenomes-Tr:CAB14156" /db_xref="GOA:P54394" /db_xref="InterPro:IPR001650" /db_xref="InterPro:IPR006054" /db_xref="InterPro:IPR006310" /db_xref="InterPro:IPR006555" /db_xref="InterPro:IPR006935" /db_xref="InterPro:IPR012337" /db_xref="InterPro:IPR013520" /db_xref="InterPro:IPR014001" /db_xref="InterPro:IPR014013" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR036397" /db_xref="SubtiList:BG11515" /db_xref="UniProtKB/Swiss-Prot:P54394" /translation="MNKQRFVVIDVETTGNSPKKGDKIIQIAAVVIENGQITERFSKY INPNKSIPAFIEQLTGISNQMVENEQPFEAVAEEVFQLLDGAYFVAHNIHFDLGFVKY ELHKAGFQLPDCEVLDTVELSRIVFPGFEGYKLTELSEELQLRHDQPHRADSDAEVTG LIFLEILEKLRQLPYPTLKQLRRLSQHFISDLTHLLDMFINENRHTEIPGYTRFSSFS VREPEAIDVRINEDENFSFEIESWEAGNEKALSELMPGYEKRDGQMMMMREVADAFAN REHALIEAPPGIGKTIGYLIPAALFAKKSKKPVIISTYSTLLQQQILTKDLPIVQDLF PFPVTAAILKGQSHYLCLYKFEQVLHEEDDNYDAVLTKAQLLVWLTETNTGDVAELNL PSGGKLLWDRLAYDDDSYKRSRSEHVIGFYERAKQIAMRSDLVITNHSLLLTDEGSHK KRLPESGTFIIDEAHHFERAASEHLGKRATYIELHTKLSRIGTLKEQGLLKKMRQLFQ RNSLPVDSFFELEEWLQHVQAESDAFFSSVHSFVKRRKPKEDLNRLVFKVNKESQDKS WSILTDGAERLCSMLTHLQQLFEAQSSLMEKHLKGMKSKTVFLADEYQRSMKGLQHYC QTLQKLFFGSDDDEAVWIEIDAKGAKNAVAIYAQPLEPGELLADQFFARKNSVVLTSA TLTVEGSFQFMIERLGLSDFFPRTMRIESPFSYDERMQVMIPKEMKSIQDTGQPEFIQ DTARYIELMAKEKQPKILVLFTSHDMLKKVHQELKHNMSASGIQLLAQGITGGSPGKL MKTFKTSNQAILLGTNHFWEGVDFPGDELTTVMIVRLPFRSPDHPLHAAKCELARKKG KNPFQTVSLPEAVLTFRQGIGRLLRSAGDKGTIIILDRRIKTAGYGRLFLDALPTTSV SEMTDSELEAYVAGEKE*" gene complement(2215269..2218064) /gene="dinG" /locus_tag="BSU_22400" /old_locus_tag="BSU22400" promotor_-35 2215737..2215741 /Source="Nicolas_upshift_promotors" /id="U1759" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.645354645354645" /psig="0.340659340659341" /xcortree=32 /SigmaFactorBS="ccgggacttccgcctgtaatcccttgtgccaagagctgaatg ccggaagcactcatgttATGCTtAAGCTcctggtgaacctttttcagcatatcatggg a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 2215738 /Source="Nicolas_upshifts" /id="U1759" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.645354645354645" /psig="0.340659340659341" /xcortree=32 /SigmaFactorBS="ccgggacttccgcctgtaatcccttgtgccaagagctgaatg ccggaagcactcatgttATGCTtAAGCTcctggtgaacctttttcagcatatcatggg a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 2215743..2215747 /Source="Nicolas_upshift_promotors" /id="U1759" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.645354645354645" /psig="0.340659340659341" /xcortree=32 /SigmaFactorBS="ccgggacttccgcctgtaatcccttgtgccaagagctgaatg ccggaagcactcatgttATGCTtAAGCTcctggtgaacctttttcagcatatcatggg a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-10 complement(2216394..2216409) /Source="Nicolas_upshift_promotors" /id="U1760" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1683 /SigmaFactorBS="gctttctttagctctgtacattcttttgtcaaacgaaGAAAA CCTAAagaagacttaaaCCGTCTAGTGTTTAAGgtgaacaaagaaagccaggataaaa g" /listShort="S850, S848, ypmA, ypmB, aspB" /listLong="S847, asnS, S846, dnaD, nth, ypoC" /label="promotor_-10" upshifts complement(2216408) /Source="Nicolas_upshifts" /id="U1760" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1683 /SigmaFactorBS="gctttctttagctctgtacattcttttgtcaaacgaaGAAAA CCTAAagaagacttaaaCCGTCTAGTGTTTAAGgtgaacaaagaaagccaggataaaa g" /listShort="S850, S848, ypmA, ypmB, aspB" /listLong="S847, asnS, S846, dnaD, nth, ypoC" promotor_-35 complement(2216422..2216431) /Source="Nicolas_upshift_promotors" /id="U1760" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1683 /SigmaFactorBS="gctttctttagctctgtacattcttttgtcaaacgaaGAAAA CCTAAagaagacttaaaCCGTCTAGTGTTTAAGgtgaacaaagaaagccaggataaaa g" /listShort="S850, S848, ypmA, ypmB, aspB" /listLong="S847, asnS, S846, dnaD, nth, ypoC" /label="promotor_-35" S_feature complement(2218065..2218189) /Source="Nicolas_S_feature" /locus_tag="new_2352467_2352591_c" /HighExp="dia15, Diami, H2O2, Heat, LBGstat, C30, G180, G135, Oxctl, MG 15" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA, SigA" /TUshortPSig="1, 1, 0.995" /TUlongSig="NA" /TUlongPSig="NA" /label="S851" CDS complement(2218190..2218573) /gene="panD" /locus_tag="BSU_22410" /old_locus_tag="BSU22410" /EC_number="4.1.1.11" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:9169598, 12600205, 15033515, 26762040" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9169598, 12600205, 15033515, 26762040; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="aspartate 1-decarboxylase" /protein_id="NP_390122.1" /db_xref="EnsemblGenomes-Gn:BSU22410" /db_xref="EnsemblGenomes-Tr:CAB14157" /db_xref="GOA:P52999" /db_xref="InterPro:IPR003190" /db_xref="InterPro:IPR009010" /db_xref="SubtiList:BG11493" /db_xref="UniProtKB/Swiss-Prot:P52999" /translation="MYRTMMSGKLHRATVTEANLNYVGSITIDEDLIDAVGMLPNEKV QIVNNNNGARLETYIIPGKRGSGVICLNGAAARLVQEGDKVIIISYKMMSDQEAASHE PKVAVLNDQNKIEQMLGNEPARTIL*" gene complement(2218190..2218573) /gene="panD" /locus_tag="BSU_22410" /old_locus_tag="BSU22410" CDS complement(2218575..2219435) /gene="panC" /locus_tag="BSU_22420" /old_locus_tag="BSU22420" /EC_number="6.3.2.1" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 17175524, 7037743; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="pantothenate synthetase" /protein_id="NP_390123.1" /db_xref="EnsemblGenomes-Gn:BSU22420" /db_xref="EnsemblGenomes-Tr:CAB14158" /db_xref="GOA:P52998" /db_xref="InterPro:IPR003721" /db_xref="InterPro:IPR004821" /db_xref="InterPro:IPR014729" /db_xref="SubtiList:BG11520" /db_xref="UniProtKB/Swiss-Prot:P52998" /translation="MRQITDISQLKEAIKQYHSEGKSIGFVPTMGFLHEGHLTLADKA RQENDAVIMSIFVNPAQFGPNEDFEAYPRDIERDAALAENAGVDILFTPDAHDMYPGE KNVTIHVERRTDVLCGRSREGHFDGVAIVLTKLFNLVKPTRAYFGLKDAQQVAVVDGL ISDFFMDIELVPVDTVREEDGLAKSSRNVYLTAEERKEAPKLYRALQTSAELVQAGER DPEAVIKAAKDIIETTSGTIDYVELYSYPELEPVNEIAGKMILAVAVAFSKARLIDNI IIDIREMERI*" gene complement(2218575..2219435) /gene="panC" /locus_tag="BSU_22420" /old_locus_tag="BSU22420" CDS complement(2219437..2220270) /gene="panB" /locus_tag="BSU_22430" /old_locus_tag="BSU22430" /EC_number="2.1.2.11" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 1844812, 8096212; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="ketopantoate hydroxymethyltransferase" /protein_id="NP_390124.1" /db_xref="EnsemblGenomes-Gn:BSU22430" /db_xref="EnsemblGenomes-Tr:CAB14159" /db_xref="GOA:P52996" /db_xref="InterPro:IPR003700" /db_xref="InterPro:IPR015813" /db_xref="SubtiList:BG11519" /db_xref="UniProtKB/Swiss-Prot:P52996" /translation="MKTKLDFLKMKESEEPIVMLTAYDYPAAKLAEQAGVDMILVGDS LGMVVLGLDSTVGVTVADMIHHTKAVKRGAPNTFIVTDMPFMSYHLSKEDTLKNAAAI VQESGADALKLEGGEGVFESIRALTLGGIPVVSHLGLTPQSVGVLGGYKVQGKDEQSA KKLIEDSIKCEEAGAMMLVLECVPAELTAKIAETLSIPVIGIGAGVKADGQVLVYHDI IGHGVERTPKFVKQYTRIDETIETAISGYVQDVRHRAFPEQKHSFQMNQTVLDGLYGG K*" gene complement(2219437..2220270) /gene="panB" /locus_tag="BSU_22430" /old_locus_tag="BSU22430" S_feature complement(2220271..2220478) /Source="Nicolas_S_feature" /locus_tag="new_2354673_2354880_c" /HighExp="LBGstat, dia15, Diami, H2O2, MG 15, Heat, Oxctl, MG 25, MG 10, G180" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA, SigA" /TUshortPSig="1, 1, 0.995" /TUlongSig="NA" /TUlongPSig="NA" /label="S852" promotor_-10 complement(2220473..2220492) /Source="Nicolas_upshift_promotors" /id="U1761" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.98001998001998" /psig=1 /xcortree=2662 /SigmaFactorBS="ctgccgatatcgaattgggctaatgTGTTGgtacaagcccgt tgatTTTGGTATACTTCCATTGGGcagtatcgcctgcgaactgcacctattattaaaa t" /listShort="S852, panB, panC, panD, S851, dinG, S850, S848, ypmA, ypmB, aspB, S847, asnS, S846, dnaD, nth, ypoC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2220478) /Source="Nicolas_upshifts" /id="U1761" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.98001998001998" /psig=1 /xcortree=2662 /SigmaFactorBS="ctgccgatatcgaattgggctaatgTGTTGgtacaagcccgt tgatTTTGGTATACTTCCATTGGGcagtatcgcctgcgaactgcacctattattaaaa t" /listShort="S852, panB, panC, panD, S851, dinG, S850, S848, ypmA, ypmB, aspB, S847, asnS, S846, dnaD, nth, ypoC" /GFF_Attribute="listLong" promotor_-35 complement(2220509..2220513) /Source="Nicolas_upshift_promotors" /id="U1761" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.98001998001998" /psig=1 /xcortree=2662 /SigmaFactorBS="ctgccgatatcgaattgggctaatgTGTTGgtacaagcccgt tgatTTTGGTATACTTCCATTGGGcagtatcgcctgcgaactgcacctattattaaaa t" /listShort="S852, panB, panC, panD, S851, dinG, S850, S848, ypmA, ypmB, aspB, S847, asnS, S846, dnaD, nth, ypoC" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2220516..2221493) /gene="birA" /locus_tag="BSU_22440" /old_locus_tag="BSU22440" /EC_number="6.3.4.15" /function="16.3: Control" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:12368242, 15459338, 28466579" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12368242, 15459338, 28466579; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="biotin acetyl-CoA-carboxylase ligase and biotin regulon repressor (BirA-biotinoyl-5'-AMP)" /protein_id="NP_390125.1" /db_xref="EnsemblGenomes-Gn:BSU22440" /db_xref="EnsemblGenomes-Tr:CAB14160" /db_xref="GOA:P0CI75" /db_xref="InterPro:IPR003142" /db_xref="InterPro:IPR004143" /db_xref="InterPro:IPR004408" /db_xref="InterPro:IPR004409" /db_xref="InterPro:IPR008988" /db_xref="InterPro:IPR013196" /db_xref="InterPro:IPR030855" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG11206" /db_xref="UniProtKB/Swiss-Prot:P0CI75" /translation="MRSTLRKDLIELFSQAGNEFISGQKISDALGCSRTAVWKHIEEL RKEGYEVEAVRRKGYRLIKKPGKLSESEIRFGLKTEVMGQHLIYHDVLSSTQKTAHEL ANNNAPEGTLVVADKQTAGRGRMSRVWHSQEGNGVWMSLILRPDIPLQKTPQLTLLAA VAVVQGIEEAAGIQTDIKWPNDILINGKKTVGILTEMQAEEDRVRSVIIGIGINVNQQ PNDFPDELKDIATSLSQAAGEKIDRAGVIQHILLCFEKRYRDYMTHGFTPIKLLWESY ALGIGTNMRARTLNGTFYGKALGIDDEGVLLLETNEGIKKIYSADIELG*" gene complement(2220516..2221493) /gene="birA" /locus_tag="BSU_22440" /old_locus_tag="BSU22440" CDS complement(2221478..2222671) /gene="cca" /locus_tag="BSU_22450" /old_locus_tag="BSU22450" /EC_number="2.7.7.72" /function="16.2: Construct biomass (Anabolism)" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:9829937, 16109934, 20360175, 22940585" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9829937, 16109934, 20360175, 22940585; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="tRNA nucleotidyltransferase" /protein_id="NP_390126.1" /db_xref="EnsemblGenomes-Gn:BSU22450" /db_xref="EnsemblGenomes-Tr:CAB14161" /db_xref="GOA:P42977" /db_xref="InterPro:IPR002646" /db_xref="InterPro:IPR023068" /db_xref="InterPro:IPR032810" /db_xref="InterPro:IPR032828" /db_xref="SubtiList:BG11208" /db_xref="UniProtKB/Swiss-Prot:P42977" /translation="MEKVFIKALPVLRILIEAGHQAYFVGGAVRDSYMKRTIGDVDIA TDAAPDQVERLFQRTVDVGKEHGTIIVLWEDETYEVTTFRTESDYVDFRRPSEVQFIS SLEEDLKRRDLTINAMAMTADGKVLDYFGGKKDIDQKVIRTVGKPEDRFQEDALRMLR AVRFMSQLGFTLSPETEEAIAKEKSLLSHVSVERKTIEFEKLLQGRASRQALQTLIQT RLYEELPGFYHKRENLISTSEFPFFSLTSREELWAALLINLGIVLKDAPLFLKAWKLP GKVIKEAIHIADTFGQSLDAMTMYRAGKKALLSAAKISQLRQNEKLDEKKLKDIQYAY QNLPIKSLKDLDITGKDLLALRNRPAGKWVSEELQWIEQAVVTGKLSNQKKHIEEWLK TCGQH*" gene complement(2221478..2222671) /gene="cca" /locus_tag="BSU_22450" /old_locus_tag="BSU22450" CDS complement(2222676..2223809) /gene="bshA" /locus_tag="BSU_22460" /old_locus_tag="BSU22460" /EC_number="2.4.1.-" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:16751541, 20308541, 22569254, 27454321, 28301954" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16751541, 20308541, 22569254, 27454321, 28301954; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="N-acetyl-alpha-D-glucosaminyl L-malate synthase;malate glycosyltransferase for bacillithiol synthesis" /protein_id="NP_390127.1" /db_xref="EnsemblGenomes-Gn:BSU22460" /db_xref="EnsemblGenomes-Tr:CAB14162" /db_xref="GOA:P42982" /db_xref="InterPro:IPR001296" /db_xref="InterPro:IPR023881" /db_xref="InterPro:IPR028098" /db_xref="PDB:5D00" /db_xref="PDB:5D01" /db_xref="SubtiList:BG11213" /db_xref="UniProtKB/Swiss-Prot:P42982" /translation="MRKLKIGITCYPSVGGSGIIATELGKQLAEKGHEIHFITSSIPF RLNTYHPNIHFHEVEVNQYAVFKYPPYDLTLASKIAEVAERENLDIIHAHYALPHAVC AYLAKQMLKRNIGIVTTLHGTDITVLGYDPSLKDLIRFAIESSDRVTAVSSALAAETY DLIKPEKKIETIYNFIDERVYLKKNTAAIKEKHGILPDEKVVIHVSNFRKVKRVQDVI RVFRNIAGKTKAKLLLVGDGPEKSTACELIRKYGLEDQVLMLGNQDRVEDLYSISDLK LLLSEKESFGLVLLEAMACGVPCIGTNIGGIPEVIKNNVSGFLVDVGDVTAATARAMS ILEDEQLSNRFTKAAIEMLENEFSSKKIVSQYEQIYADLAEPE*" gene complement(2222676..2223809) /gene="bshA" /locus_tag="BSU_22460" /old_locus_tag="BSU22460" CDS complement(2223806..2224516) /gene="bshBA" /locus_tag="BSU_22470" /old_locus_tag="BSU22470" /EC_number="3.5.1.-" /function="4.10: Glutathione and analogs" /experiment="publication(s) with functional evidences, PMID:11004195, 20308541, 23894131, 28117687" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11004195, 20308541, 23894131, 28117687; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="N-acetyl-alpha-D-glucosaminyl L-malate deacetylase 1; malate N-acetylglucosamine N-acetyl hydrolase" /protein_id="NP_390128.2" /db_xref="EnsemblGenomes-Gn:BSU22470" /db_xref="EnsemblGenomes-Tr:CAB14163" /db_xref="GOA:P42981" /db_xref="InterPro:IPR003737" /db_xref="InterPro:IPR023842" /db_xref="InterPro:IPR024078" /db_xref="SubtiList:BG11212" /db_xref="UniProtKB/Swiss-Prot:P42981" /translation="MYNADVLAFGAHSDDVEIGMGGTIAKFVKQEKKVMICDLTEAEL SSNGTVSLRKEEAAEAARILGADKRIQLTLPDRGLIMSDQAIRSIVTVIRICRPKAVF MPYKKDRHPDHGNAAALVEEAIFSAGIHKYKDEKSLPAHKVSKVYYYMINGFHQPDFV IDISDTIEAKKQSLNAYKSQFIPSKDSVSTPLTNGYIEIVEAREKLYGKEAGVEYAEG FFSKRMLMLDHDVLGGEQ*" gene complement(2223806..2224516) /gene="bshBA" /locus_tag="BSU_22470" /old_locus_tag="BSU22470" CDS complement(2224509..2224922) /gene="mgsA" /locus_tag="BSU_22480" /old_locus_tag="BSU22480" /EC_number="4.2.3.3" /function="16.3: Control" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:9489667, 10368300, 10715115, 11423008, 15489434, 21992469, 23894131, 28807600" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9489667, 10368300, 10715115, 11423008, 15489434, 21992469, 23894131, 28807600; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="methylglyoxal synthase" /protein_id="NP_390129.1" /db_xref="EnsemblGenomes-Gn:BSU22480" /db_xref="EnsemblGenomes-Tr:CAB14164" /db_xref="GOA:P42980" /db_xref="InterPro:IPR004363" /db_xref="InterPro:IPR011607" /db_xref="InterPro:IPR018148" /db_xref="InterPro:IPR036914" /db_xref="SubtiList:BG11211" /db_xref="UniProtKB/Swiss-Prot:P42980" /translation="MKIALIAHDKKKQDMVQFTTAYRDILKNHDLYATGTTGLKIHEA TGLQIERFQSGPLGGDQQIGALIAANALDLVIFLRDPLTAQPHEPDVSALIRLCDVYS IPLATNMGTAEILVRTLDEGVFEFRDLLRGEEPNV*" gene complement(2224509..2224922) /gene="mgsA" /locus_tag="BSU_22480" /old_locus_tag="BSU22480" CDS complement(2224938..2225741) /gene="dapB" /locus_tag="BSU_22490" /old_locus_tag="BSU22490" /EC_number="1.17.1.8" /function="16.13: Shape" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 6422596, 9398235, 12682299, 20503968; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="(4S)-4-hydroxy-2,3,4, 5-tetrahydro-(2S)-dipicolinic acid (HTPA) dehydratase reductase" /protein_id="NP_390130.1" /db_xref="EnsemblGenomes-Gn:BSU22490" /db_xref="EnsemblGenomes-Tr:CAB14165" /db_xref="GOA:P42976" /db_xref="InterPro:IPR000846" /db_xref="InterPro:IPR022663" /db_xref="InterPro:IPR022664" /db_xref="InterPro:IPR023940" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG11207" /db_xref="UniProtKB/Swiss-Prot:P42976" /translation="MSNETIKLVIAGPRGRMGQEAVKLAERTPHFDLVGAIDHTYDQQ KLSDVMPVESDAFIYTDIHACFTETQPDVLIDLTTPEIGKVHTKIALEHGVRPVVGTT GFSEADLKELTSLTEEKGIGAIIAPNFALGAILMMKFSKMAANYFEDVEIIELHHDQK LDAPSGTALKTAEMISEVRKEKQQGHPDEKEILPGARGAEQNGIRLHSVRLPGLIAHQ EVMFGMDGQTLQIRHDSYNRASFMSGVKLSVEQVMKIDQLVYGLENIID*" gene complement(2224938..2225741) /gene="dapB" /locus_tag="BSU_22490" /old_locus_tag="BSU22490" CDS complement(2225753..2226088) /gene="ypjD" /locus_tag="BSU_22500" /old_locus_tag="BSU22500" /function="16.3: Control" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1c: Function from experimental evidences in the studied genus; PubMedId: 16390452, 20529853, 20944217, 21733847, 24339782, 26920050, 28117687; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="oxidized nucleotide pyrophosphohydrolase" /protein_id="NP_390131.1" /db_xref="EnsemblGenomes-Gn:BSU22500" /db_xref="EnsemblGenomes-Tr:CAB14166" /db_xref="InterPro:IPR004518" /db_xref="InterPro:IPR012359" /db_xref="PDB:2GTA" /db_xref="SubtiList:BG11210" /db_xref="UniProtKB/Swiss-Prot:P42979" /translation="MSDKTMKDIQAEVDRYIGQFKEGYFSPLAMMARLTEELGELARE VNHRYGEKPKKATEDDKSMEEEIGDVLFVLVCLANSLDISLEEAHDRVMHKFNTRDKD RWTRKEEGK*" gene complement(2225753..2226088) /gene="ypjD" /locus_tag="BSU_22500" /old_locus_tag="BSU22500" promotor_-10 complement(2226108..2226127) /Source="Nicolas_upshift_promotors" /id="U1762" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.632367632367632" /psig=1 /xcortree=2567 /SigmaFactorBS="atgaaaaagaaaacagcaaacgtgcttaaaCATTTGTCaaac gtatctgaaTTAGCTAACATGTAAGAGGAtgataggaggtttcgttcagtgagtgata a" /listShort="ypjD, dapB, mgsA, ypjG, ypjH, cca, birA, S852, panB, panC, panD, S851, dinG, S850, S848, ypmA, ypmB, aspB" /listLong="S847, asnS, S846, dnaD, nth, ypoC" /label="promotor_-10" upshifts complement(2226118) /Source="Nicolas_upshifts" /id="U1762" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.632367632367632" /psig=1 /xcortree=2567 /SigmaFactorBS="atgaaaaagaaaacagcaaacgtgcttaaaCATTTGTCaaac gtatctgaaTTAGCTAACATGTAAGAGGAtgataggaggtttcgttcagtgagtgata a" /listShort="ypjD, dapB, mgsA, ypjG, ypjH, cca, birA, S852, panB, panC, panD, S851, dinG, S850, S848, ypmA, ypmB, aspB" /listLong="S847, asnS, S846, dnaD, nth, ypoC" promotor_-35 complement(2226141..2226148) /Source="Nicolas_upshift_promotors" /id="U1762" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.632367632367632" /psig=1 /xcortree=2567 /SigmaFactorBS="atgaaaaagaaaacagcaaacgtgcttaaaCATTTGTCaaac gtatctgaaTTAGCTAACATGTAAGAGGAtgataggaggtttcgttcagtgagtgata a" /listShort="ypjD, dapB, mgsA, ypjG, ypjH, cca, birA, S852, panB, panC, panD, S851, dinG, S850, S848, ypmA, ypmB, aspB" /listLong="S847, asnS, S846, dnaD, nth, ypoC" /label="promotor_-35" promotor_-35 2226157..2226164 /Source="Nicolas_upshift_promotors" /id="U1763" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.883116883116883" /psig=1 /xcortree=2405 /SigmaFactorBS="ctaattcagatacgtttgacaaatgtttaagcaCGTTTGCTg ttttctttttcaTCCACTATAATATAAACGCTatctaatggaaggaaaaggggttttg t" /listShort="ypjC" /GFF_Attribute="listLong" /label="promotor_-35" misc_feature complement(2226173..2226192) /Source="Nicolas_upshift_promotors" /id="U1764" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.415584415584416" /psig="0.995004995004995" /xcortree=2307 /SigmaFactorBS="tttttaatctaatttctccaagcatcacacaaaacccctttt ccttccattagatagcgtTTATATTATAGTGGATGAAAaagaaaacagcaaacgtgct t" /listShort="ypjD, dapB, mgsA, ypjG, ypjH, cca, birA, S852, panB, panC, panD, S851, dinG, S850, S848, ypmA" /listLong="ypmB, aspB, S847, asnS, S846, dnaD, nth, ypoC" /label="promotor_single_box" /note="Geneious type: promotor_single_box" promotor_-10 2226178..2226197 /Source="Nicolas_upshift_promotors" /id="U1763" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.883116883116883" /psig=1 /xcortree=2405 /SigmaFactorBS="ctaattcagatacgtttgacaaatgtttaagcaCGTTTGCTg ttttctttttcaTCCACTATAATATAAACGCTatctaatggaaggaaaaggggttttg t" /listShort="ypjC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2226184 /Source="Nicolas_upshifts" /id="U1763" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.883116883116883" /psig=1 /xcortree=2405 /SigmaFactorBS="ctaattcagatacgtttgacaaatgtttaagcaCGTTTGCTg ttttctttttcaTCCACTATAATATAAACGCTatctaatggaaggaaaaggggttttg t" /listShort="ypjC" /GFF_Attribute="listLong" upshifts complement(2226192) /Source="Nicolas_upshifts" /id="U1764" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.415584415584416" /psig="0.995004995004995" /xcortree=2307 /SigmaFactorBS="tttttaatctaatttctccaagcatcacacaaaacccctttt ccttccattagatagcgtTTATATTATAGTGGATGAAAaagaaaacagcaaacgtgct t" /listShort="ypjD, dapB, mgsA, ypjG, ypjH, cca, birA, S852, panB, panC, panD, S851, dinG, S850, S848, ypmA" /listLong="ypmB, aspB, S847, asnS, S846, dnaD, nth, ypoC" CDS 2226228..2227100 /gene="ypjC" /locus_tag="BSU_22510" /old_locus_tag="BSU22510" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative integral inner membrane protein" /protein_id="NP_390132.2" /db_xref="EnsemblGenomes-Gn:BSU22510" /db_xref="EnsemblGenomes-Tr:CAB14167" /db_xref="GOA:P42978" /db_xref="InterPro:IPR003740" /db_xref="InterPro:IPR019264" /db_xref="SubtiList:BG11209" /db_xref="UniProtKB/Swiss-Prot:P42978" /translation="MLGEIRLKNIFFILIGAAIFSFGLVHFNMQNNLAEGGFTGITLL LYALFHISPSISNLVLNIPIFFIGWRLLGRTMFVYTLVGTVALSLFLSIFQRYEIHMP LQHDLALAALFAGVFIGAGLGIIFKFGGTTGGVDIIARLVNKYFGIPMGRTMFAFDAC VIILSLLTYLSYKEAMYTLVAVFVAARLIDFIQEGGYAAKGATIISSKNDLIQKKILE EMERGVTILKGQGSYTKEDIDVLYCVVPKNELVMLKSVINSIDPHAFVAVSDVHDVLG EGFTLDENKNPLPR*" gene 2226228..2227100 /gene="ypjC" /locus_tag="BSU_22510" /old_locus_tag="BSU22510" CDS complement(2227142..2227936) /gene="ypjB" /locus_tag="BSU_22520" /old_locus_tag="BSU22520" /function="16.5: Explore" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:12662922" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12662922; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="sporulation septum-associated protein" /protein_id="NP_390133.1" /db_xref="EnsemblGenomes-Gn:BSU22520" /db_xref="EnsemblGenomes-Tr:CAB14168" /db_xref="GOA:P54393" /db_xref="InterPro:IPR014231" /db_xref="SubtiList:BG11500" /db_xref="UniProtKB/Swiss-Prot:P54393" /translation="MKRKLTICLLIALIFYNGNAKAAERGSLEELNDLSDTVFQMTRQ AKYEEALQVLEYFEKTLKSAEKKQQDPMLTGAQIRQITLGYNDMVRSLKQADTSDTQK LRAAAQFRMLMDAVDNRSDPLWGSLEKPIMEAFTELKRDVQKNGSTSFHEKWNEFISL YDLIYPSLTIDVSEDQLETVGKHIDVIEQEEFQQMTESTKLERLSLLQHDLKNVFDRV EEDDADPSLLWVIITTGSIIITALTYVGYRKYKAEKNKLKKRDYPK*" gene complement(2227142..2227936) /gene="ypjB" /locus_tag="BSU_22520" /old_locus_tag="BSU22520" downshifts complement(2227167) /Source="Nicolas_upshifts" /id="D1176" /incds=0 /nref=4 /ntot=106 /MaxReadThrough="1.96946" /MaxDrop="3.51024" /score="34.9661402" /energy="-11.3" /TU="NA" /idTUdmin="U1765" /TUdmin=198 /isTUend="FALSE" S_feature complement(2227937..2228004) /Source="Nicolas_S_feature" /locus_tag="new_2362339_2362406_c" /HighExp="LBGstat, C30, S0, LoTm, G180, G135, G150, Oxctl, Paraq, LPh" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.866" /TUlongSig="SigH, SigA" /TUlongPSig="1, 0.999" /label="S853" CDS complement(2228005..2228562) /gene="ypjA" /locus_tag="BSU_22530" /old_locus_tag="BSU22530" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 15849754, 16850406; Product type m:membrane component" /codon_start=1 /transl_table=11 /product="conserved integral inner membrane protein of unknown function" /protein_id="NP_390134.1" /db_xref="EnsemblGenomes-Gn:BSU22530" /db_xref="EnsemblGenomes-Tr:CAB14169" /db_xref="GOA:P54392" /db_xref="InterPro:IPR009845" /db_xref="SubtiList:BG11499" /db_xref="UniProtKB/Swiss-Prot:P54392" /translation="MLILVLAINFLGTVYGYYWYLPQLLETPARFLIFVPDSPTATFF FLFVLLAFLMKRNAPLLEALALVTLVKYGLWAVAMNFLVLAVTGDLPWEGYMLIASHF AMAVQGVLYSPYFRFSFWHLAIAAVWTLHNDVIDYLFDMMPQYSMLSDYMTEIGYGTF WLSIFSIALAYFLVVSKKQTKLELM*" gene complement(2228005..2228562) /gene="ypjA" /locus_tag="BSU_22530" /old_locus_tag="BSU22530" S_feature complement(2228563..2228642) /Source="Nicolas_S_feature" /locus_tag="new_2362965_2363044_c" /HighExp="C30, UNK1, G135, BMM, G150, G180, Oxctl, LoTm, Paraq, S0" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.866" /TUlongSig="SigH, SigA" /TUlongPSig="1, 0.999" /label="S854" downshifts complement(2228687) /Source="Nicolas_upshifts" /id="D1177" /incds=0 /nref=131 /ntot=215 /MaxReadThrough="3.97061" /MaxDrop="6.41485" /score="13.3880841" /energy="-8" /TU="U1765" /idTUdmin="U1767" /TUdmin="-2" /isTUend="TRUE" CDS complement(2228709..2229476) /gene="qcrC" /locus_tag="BSU_22540" /old_locus_tag="BSU22540" /function="16.10: Respire" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 7592464, 8647852, 12446663, 12615356, 19114526; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="menaquinol:cytochrome c oxidoreductase (cytochrome cc subunit)" /protein_id="NP_390135.1" /db_xref="EnsemblGenomes-Gn:BSU22540" /db_xref="EnsemblGenomes-Tr:CAB14170" /db_xref="GOA:P46913" /db_xref="InterPro:IPR005798" /db_xref="InterPro:IPR009056" /db_xref="InterPro:IPR012049" /db_xref="InterPro:IPR027387" /db_xref="InterPro:IPR036150" /db_xref="InterPro:IPR036909" /db_xref="SubtiList:BG11327" /db_xref="UniProtKB/Swiss-Prot:P46913" /translation="MHRGKGMKFVGDSRIPAEKKPNIPKDYSEYPGKTEAFWPNFLLK EWMVGAVFLIGFLVLTIVHQPPLERMADPTDTGYIPLPDWYFLFLYQLLKYEYAAGSF TVVGAMIMPGLAFGALLLAPFLDRGTERRPWKRPVAVGMMLLAISAAVFLTWQSVATH DWAKAEEQGKITKEADIDTNAEGYKVFKEQGCISCHGDNLQGGAAGPSLVDSGLKPDE IKKIAVEGKGKMPAGVFKGNDKQLEELAKFISETTAK*" gene complement(2228709..2229476) /gene="qcrC" /locus_tag="BSU_22540" /old_locus_tag="BSU22540" CDS complement(2229511..2230185) /gene="qcrB" /locus_tag="BSU_22550" /old_locus_tag="BSU22550" /function="16.10: Respire" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 7592464, 8647852, 12446663, 12615356, 15849754, 16850406; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="menaquinol:cytochrome c oxidoreductase (cytochrome b subunit)" /protein_id="NP_390136.1" /db_xref="EnsemblGenomes-Gn:BSU22550" /db_xref="EnsemblGenomes-Tr:CAB14171" /db_xref="GOA:P46912" /db_xref="InterPro:IPR005797" /db_xref="InterPro:IPR016174" /db_xref="InterPro:IPR023530" /db_xref="InterPro:IPR027387" /db_xref="SubtiList:BG11326" /db_xref="UniProtKB/Swiss-Prot:P46912" /translation="MLNKIYDWVDERLDITPMWRDIADHEVPEHVNPAHHFSAFVYCF GGLTFFVTVIQVLSGMFLTMYYVPDIKNAWESVYYLQNEVAFGQIVRGMHHWGASLVI VMMFLHTLRVFFQGAYKKPRELNWIVGVLIFFVMLGLGFTGYLLPWDMKALFATKVGL QIAEATPLIGTQVKTLLAGHPDIVGAQTLTRFFAIHVFFLPAALFGLMAAHFIMIRKQ GISGPL*" gene complement(2229511..2230185) /gene="qcrB" /locus_tag="BSU_22550" /old_locus_tag="BSU22550" CDS complement(2230187..2230690) /gene="qcrA" /locus_tag="BSU_22560" /old_locus_tag="BSU22560" /EC_number="1.10.2.-" /function="16.10: Respire" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 7592464, 8647852, 12446663, 12615356, 24652282, 27503613; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="menaquinol:cytochrome c oxidoreductase (iron-sulfur subunit)" /protein_id="NP_390137.1" /db_xref="EnsemblGenomes-Gn:BSU22560" /db_xref="EnsemblGenomes-Tr:CAB14172" /db_xref="GOA:P46911" /db_xref="InterPro:IPR006311" /db_xref="InterPro:IPR014349" /db_xref="InterPro:IPR014909" /db_xref="InterPro:IPR017941" /db_xref="InterPro:IPR036922" /db_xref="SubtiList:BG11325" /db_xref="UniProtKB/Swiss-Prot:P46911" /translation="MGGKHDISRRQFLNYTLTGVGGFMAASMLMPMVRFALDPVLKST GKQDMVQVVSVDELTKEPQRFDFKINQVDAWYESEESRSAWVFKNGDEIVALSPICKH LGCTVNWNSDPKNPNKFFCPCHYGLYEKDGTNVPGTPPLAPLDHYEQEVKDGFLYLGK AKPKGEG*" gene complement(2230187..2230690) /gene="qcrA" /locus_tag="BSU_22560" /old_locus_tag="BSU22560" downshifts 2230699 /Source="Nicolas_upshifts" /id="D1178" /incds=0 /nref=1 /ntot=80 /MaxReadThrough="1.24169" /MaxDrop="3.42621" /score="0.352684802" /energy="-11.5" /TU="NA" /idTUdmin="U1763" /TUdmin=3608 /isTUend="FALSE" promotor_-10 complement(2230754..2230773) /Source="Nicolas_upshift_promotors" /id="U1765" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.595404595404595" /psig="0.866133866133866" /xcortree=512 /SigmaFactorBS="ataaacaatattttggctaTATTGACCttgctgagagattcA TATATTATGAGGGTGTCTAgagttattgcaatattttctattttagtcagtttgcagg g" /listShort="qcrA, qcrB, qcrC, S854, ypjA, S853, ypjB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2230754) /Source="Nicolas_upshifts" /id="U1765" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.595404595404595" /psig="0.866133866133866" /xcortree=512 /SigmaFactorBS="ataaacaatattttggctaTATTGACCttgctgagagattcA TATATTATGAGGGTGTCTAgagttattgcaatattttctattttagtcagtttgcagg g" /listShort="qcrA, qcrB, qcrC, S854, ypjA, S853, ypjB" /GFF_Attribute="listLong" promotor_-35 complement(2230788..2230795) /Source="Nicolas_upshift_promotors" /id="U1765" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.595404595404595" /psig="0.866133866133866" /xcortree=512 /SigmaFactorBS="ataaacaatattttggctaTATTGACCttgctgagagattcA TATATTATGAGGGTGTCTAgagttattgcaatattttctattttagtcagtttgcagg g" /listShort="qcrA, qcrB, qcrC, S854, ypjA, S853, ypjB" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2230833..2231279) /gene="ypiF" /locus_tag="BSU_22570" /old_locus_tag="BSU22570" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 15743949" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_390138.1" /db_xref="EnsemblGenomes-Gn:BSU22570" /db_xref="EnsemblGenomes-Tr:CAB14173" /db_xref="InterPro:IPR019615" /db_xref="SubtiList:BG11498" /db_xref="UniProtKB/Swiss-Prot:P54391" /translation="MRWRITDAKDYLQAKDYIDTAVIPLINIRVNNHFKMAAEKGEFT QLLSEELERQLKGRVYLLPPYTYVDRNEITVQGLKDLREELITEFPHVVLLTSDESWR AEDALGKMIVTSSVPLEHLNDSLKRKILDERTAEILNVLLQLWSTL*" gene complement(2230833..2231279) /gene="ypiF" /locus_tag="BSU_22570" /old_locus_tag="BSU22570" downshifts 2231282 /Source="Nicolas_upshifts" /id="D1179" /incds=0 /nref=2 /ntot=54 /MaxReadThrough="0.94679" /MaxDrop="2.794" /score="0.352684802" /energy="-11.5" /TU="NA" /idTUdmin="U1763" /TUdmin=4191 /isTUend="FALSE" CDS complement(2231334..2231873) /gene="ypiB" /locus_tag="BSU_22580" /old_locus_tag="BSU22580" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 16847875" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_390139.1" /db_xref="EnsemblGenomes-Gn:BSU22580" /db_xref="EnsemblGenomes-Tr:CAB14174" /db_xref="InterPro:IPR011188" /db_xref="InterPro:IPR014957" /db_xref="InterPro:IPR014963" /db_xref="SubtiList:BG11497" /db_xref="UniProtKB/Swiss-Prot:P54390" /translation="MQTPVSVNEKKDFIRWFLNHYQLKRRECVWILNYLMSHDSLMEK VHFVEQAEFCPRGIIMSTHCVEEVPFRFYKENVMTTDAEKSFHDIRLNKQQDLFIQLN FRSAYSSPEYAAVLESNPHIPKNLFENKKDQGLAEQILEHAISTFQREKLLKDIDDAL DRHDKEAFEQLSRQLNQLT*" gene complement(2231334..2231873) /gene="ypiB" /locus_tag="BSU_22580" /old_locus_tag="BSU22580" downshifts complement(2231347) /Source="Nicolas_upshifts" /id="D1180" /incds=0 /nref=84 /ntot=250 /MaxReadThrough="5.68366" /MaxDrop="5.48142" /score="16.8021869" /energy="-11.2" /TU="U1766,U1767" /idTUdmin="U1768" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(2231906..2231924) /Source="Nicolas_upshift_promotors" /id="U1766" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp=1 /psig=1 /xcortree=519 /SigmaFactorBS="attttgcgaatcgaggatgaattttctagataaGCAGGAATA ttaaccattcaTGTGGAACATATAAGTATAtagattatacgaacgatagaggagggaa t" /listShort="ypiB, ypiF, qcrA, qcrB" /listLong="qcrC, S854, ypjA, S853, ypjB" /label="promotor_-10" upshifts complement(2231917) /Source="Nicolas_upshifts" /id="U1766" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp=1 /psig=1 /xcortree=519 /SigmaFactorBS="attttgcgaatcgaggatgaattttctagataaGCAGGAATA ttaaccattcaTGTGGAACATATAAGTATAtagattatacgaacgatagaggagggaa t" /listShort="ypiB, ypiF, qcrA, qcrB" /listLong="qcrC, S854, ypjA, S853, ypjB" promotor_-35 complement(2231936..2231944) /Source="Nicolas_upshift_promotors" /id="U1766" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp=1 /psig=1 /xcortree=519 /SigmaFactorBS="attttgcgaatcgaggatgaattttctagataaGCAGGAATA ttaaccattcaTGTGGAACATATAAGTATAtagattatacgaacgatagaggagggaa t" /listShort="ypiB, ypiF, qcrA, qcrB" /listLong="qcrC, S854, ypjA, S853, ypjB" /label="promotor_-35" CDS complement(2231945..2233216) /gene="ypiA" /locus_tag="BSU_22590" /old_locus_tag="BSU22590" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_390140.1" /db_xref="EnsemblGenomes-Gn:BSU22590" /db_xref="EnsemblGenomes-Tr:CAB14175" /db_xref="InterPro:IPR011990" /db_xref="InterPro:IPR013026" /db_xref="InterPro:IPR019734" /db_xref="SubtiList:BG11496" /db_xref="UniProtKB/Swiss-Prot:P54389" /translation="MNTLIQEAIKLVEAGETEKGLNTLSKAEKQLHDEDKAIAAQLYY EWGDVEKAISLISDLHDLYPNETELTNFYAELLIDIDEEEKALAVLETIPETDPSYPE SLLLMADLYQMQGLFEVSEQKLFQAKSILDNEPVIDFALGELYFAQGAYAKAVQYFKT TAEEQSEIGGVNVHQRLAESLSASGEFEDAIPWYEKAVDENPDPNTIFGYGFTALQAG LVKTAIKQLSDLKELDPSYTSLYMPLSKSYEAEGMYEEALKTAKEGIRYDEYNKELFL YAAKMALKIGKSEEGKKLLQEALALDPGFVEALHTLLAVYHKEEDYDQIIDLIQEVRS YGEEDPKYNWYLASAYTELEQYEEAKQSFEAAYLHYREDRDFLYEYASFLLEEGLQKE ALPLLKKVLEMDGANEELEETILRIEDEFSR*" gene complement(2231945..2233216) /gene="ypiA" /locus_tag="BSU_22590" /old_locus_tag="BSU22590" S_feature complement(2233217..2233284) /Source="Nicolas_S_feature" /locus_tag="new_2367619_2367686_c" /HighExp="dia15, Diami, dia5, Etha, H2O2, T1.30H, LPhT, T0.30H, T3.0H, S3" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA, SigEF, SigA" /TUshortPSig="0.999, 0.999, 0.999, 1" /TUlongSig="Sig-, Sig-, SigA, SigA, SigA, SigA, SigA, SigA" /TUlongPSig="0.042, 0.047, 0.994, 0.999, 1, 0.999, 1, 0.998" /label="S855" promotor_-10 complement(2233281..2233300) /Source="Nicolas_upshift_promotors" /id="U1767" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.977022977022977" /psig="0.999000999001" /xcortree=2047 /SigmaFactorBS="ttcccttccgtacagaagcatctTATTTGCCgggggcattcg tcTGAATTATGATAAGATTAACccgaacaaataaagctttttttgtatggttgatgtt g" /listShort="S855, ypiA, ypiB, ypiF, qcrA, qcrB, qcrC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2233284) /Source="Nicolas_upshifts" /id="U1767" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.977022977022977" /psig="0.999000999001" /xcortree=2047 /SigmaFactorBS="ttcccttccgtacagaagcatctTATTTGCCgggggcattcg tcTGAATTATGATAAGATTAACccgaacaaataaagctttttttgtatggttgatgtt g" /listShort="S855, ypiA, ypiB, ypiF, qcrA, qcrB, qcrC" /GFF_Attribute="listLong" promotor_-35 complement(2233314..2233321) /Source="Nicolas_upshift_promotors" /id="U1767" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.977022977022977" /psig="0.999000999001" /xcortree=2047 /SigmaFactorBS="ttcccttccgtacagaagcatctTATTTGCCgggggcattcg tcTGAATTATGATAAGATTAACccgaacaaataaagctttttttgtatggttgatgtt g" /listShort="S855, ypiA, ypiB, ypiF, qcrA, qcrB, qcrC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(2233351..2233370) /Source="Nicolas_upshift_promotors" /id="U1768" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.788211788211788" /psig="0.999000999001" /xcortree=569 /SigmaFactorBS="ctgtacagagggcgatcttccttttttcaTTTTCTATctcaa gatctTTTGGTAAACTAATAAGACTcaataattcccttccgtacagaagcatcttatt t" /listShort="S855, ypiA, ypiB" /listLong="ypiF, qcrA, qcrB, qcrC, S854, ypjA, S853, ypjB" /label="promotor_-10" upshifts complement(2233357) /Source="Nicolas_upshifts" /id="U1768" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.788211788211788" /psig="0.999000999001" /xcortree=569 /SigmaFactorBS="ctgtacagagggcgatcttccttttttcaTTTTCTATctcaa gatctTTTGGTAAACTAATAAGACTcaataattcccttccgtacagaagcatcttatt t" /listShort="S855, ypiA, ypiB" /listLong="ypiF, qcrA, qcrB, qcrC, S854, ypjA, S853, ypjB" S_feature complement(2233359..2233503) /Source="Nicolas_S_feature" /locus_tag="new_2367761_2367905_c" /HighExp="S3, LoTm, M9-stat, S4, Etha, S5, T5.0H, BT, B36, S6" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigEF, SigA, Sig-, SigA" /TUshortPSig="0.999, 1, 0.047, 0.994" /TUlongSig="Sig-, SigA, SigA, SigA, SigA, SigA" /TUlongPSig="0.042, 0.999, 1, 0.999, 1, 0.998" /label="S856" promotor_-35 complement(2233381..2233388) /Source="Nicolas_upshift_promotors" /id="U1768" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.788211788211788" /psig="0.999000999001" /xcortree=569 /SigmaFactorBS="ctgtacagagggcgatcttccttttttcaTTTTCTATctcaa gatctTTTGGTAAACTAATAAGACTcaataattcccttccgtacagaagcatcttatt t" /listShort="S855, ypiA, ypiB" /listLong="ypiF, qcrA, qcrB, qcrC, S854, ypjA, S853, ypjB" /label="promotor_-35" promotor_-10 complement(2233485..2233503) /Source="Nicolas_upshift_promotors" /id="U1769" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=983 /SigmaFactorBS="aaaaaatcctgaagttttacttcaggattttttatgcagATC ATAattcgaggcgaaaaaACATAGCTTGTCTTATAGAacggatagaaaaacgaaaagg g" /listShort="S856, S855, ypiA" /listLong="ypiB, ypiF, qcrA, qcrB, qcrC" /label="promotor_-10" upshifts complement(2233503) /Source="Nicolas_upshifts" /id="U1769" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=983 /SigmaFactorBS="aaaaaatcctgaagttttacttcaggattttttatgcagATC ATAattcgaggcgaaaaaACATAGCTTGTCTTATAGAacggatagaaaaacgaaaagg g" /listShort="S856, S855, ypiA" /listLong="ypiB, ypiF, qcrA, qcrB, qcrC" promotor_-35 complement(2233519..2233524) /Source="Nicolas_upshift_promotors" /id="U1769" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=983 /SigmaFactorBS="aaaaaatcctgaagttttacttcaggattttttatgcagATC ATAattcgaggcgaaaaaACATAGCTTGTCTTATAGAacggatagaaaaacgaaaagg g" /listShort="S856, S855, ypiA" /listLong="ypiB, ypiF, qcrA, qcrB, qcrC" /label="promotor_-35" CDS complement(2233552..2234838) /gene="aroA" /locus_tag="BSU_22600" /old_locus_tag="BSU22600" /EC_number="2.5.1.19" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 3106153, 22938038, 24628944; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvoylshikimate-3-phosphate synthase)" /protein_id="NP_390141.1" /db_xref="EnsemblGenomes-Gn:BSU22600" /db_xref="EnsemblGenomes-Tr:CAB14176" /db_xref="GOA:P20691" /db_xref="InterPro:IPR001986" /db_xref="InterPro:IPR006264" /db_xref="InterPro:IPR013792" /db_xref="InterPro:IPR023193" /db_xref="InterPro:IPR036968" /db_xref="SubtiList:BG10294" /db_xref="UniProtKB/Swiss-Prot:P20691" /translation="MKRDKVQTLHGEIHIPGDKSISHRSVMFGALAAGTTTVKNFLPG ADCLSTIDCFRKMGVHIEQSSSDVVIHGKGIDALKEPESLLDVGNSGTTIRLMLGILA GRPFYSAVAGDESIAKRPMKRVTEPLKKMGAKIDGRAGGEFTPLSVSGASLKGIDYVS PVASAQIKSAVLLAGLQAEGTTTVTEPHKSRDHTERMLSAFGVKLSEDQTSVSIAGGQ KLTAADIFVPGDISSAAFFLAAGAMVPNSRIVLKNVGLNPTRTGIIDVLQNMGAKLEI KPSADSGAEPYGDLIIETSSLKAVEIGGDIIPRLIDEIPIIALLATQAEGTTVIKDAA ELKVKETNRIDTVVSELRKLGAEIEPTADGMKVYGKQTLKGGAAVSSHGDHRIGMMLG IASCITEEPIEIEHTDAIHVSYPTFFEHLNKLSKKS*" gene complement(2233552..2234838) /gene="aroA" /locus_tag="BSU_22600" /old_locus_tag="BSU22600" downshifts complement(2233575) /Source="Nicolas_upshifts" /id="D1181" /incds=0 /nref=68 /ntot=212 /MaxReadThrough="3.64462" /MaxDrop="4.25336" /score="16.8021869" /energy="-11.2" /TU="U1770,U1772,U1773" /idTUdmin="U1775" /TUdmin="-6" /isTUend="TRUE" CDS complement(2234849..2235964) /gene="tyrA" /locus_tag="BSU_22610" /old_locus_tag="BSU22610" /EC_number="1.3.1.12" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:3106153, 3121591" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 3106153, 3121591; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="prephenate dehydrogenase" /protein_id="NP_390142.1" /db_xref="EnsemblGenomes-Gn:BSU22610" /db_xref="EnsemblGenomes-Tr:CAB14177" /db_xref="GOA:P20692" /db_xref="InterPro:IPR002912" /db_xref="InterPro:IPR003099" /db_xref="InterPro:IPR008927" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG10293" /db_xref="UniProtKB/Swiss-Prot:P20692" /translation="MNQMKDTILLAGLGLIGGSIALAIKKNHPGKRIIGIDISDEQAV AALKLGVIDDRADSFISGVKEAATVIIATPVEQTLVMLEELAHSGIEHELLITDVGST KQKVVDYADQVLPSRYQFVGGHPMAGSHKSGVAAAKEFLFENAFYILTPGQKTDKQAV EQLKNLLKGTNAHFVEMSPEEHDGVTSVISHFPHIVAASLVHQTHHSENLYPLVKRFA AGGFRDITRIASSSPAMWRDILLHNKDKILDRFDEWIREIDKIRTYVEQEDAENLFRY FKTAKDYRDGLPLRQKGAIPAFYDLYVDVPDHPGVISEITAILAAERISITNIRIIET REDINGILRISFQSDDDRKRAEQCIEARAEYETFYAD*" gene complement(2234849..2235964) /gene="tyrA" /locus_tag="BSU_22610" /old_locus_tag="BSU22610" CDS complement(2236013..2237095) /gene="hisC" /locus_tag="BSU_22620" /old_locus_tag="BSU22620" /EC_number="2.6.1.5" /EC_number="2.6.1.9" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:4431, 418816, 824269, 11518529, 15102328" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 4431, 418816, 824269, 11518529, 15102328; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="histidinol-phosphate aminotransferase; tyrosine/phenylalanine aminotransferase (promiscuous)" /protein_id="NP_390143.2" /db_xref="EnsemblGenomes-Gn:BSU22620" /db_xref="EnsemblGenomes-Tr:CAB14178" /db_xref="GOA:P17731" /db_xref="InterPro:IPR001917" /db_xref="InterPro:IPR004839" /db_xref="InterPro:IPR005861" /db_xref="InterPro:IPR015421" /db_xref="InterPro:IPR015422" /db_xref="InterPro:IPR015424" /db_xref="SubtiList:BG10292" /db_xref="UniProtKB/Swiss-Prot:P17731" /translation="MRIKEHLKQLKPYQPGKPIEAVKSEYGLDKVVKLASNENPYGCS EAAKEALHHEIQQLALYPDGYSAALRTRLSKHLNVSETSLIFGNGSDEIIQIICRAFL NDKTNTVTAAPTFPQYKHNAVIEGAEVREIALRPDGSHDLDAMLEAIDEQTQVVWICS PNNPTGTYTSEGELLAFLERVPSRVLVVLDEAYYEYVTAEDYPETVPLLSKYSNLMIL RTFSKAYGLAALRVGYGIADENLIRQIEPAREPFNTSRLGQAAAIAALDDQAFIASCV EQNNAGLQQYYDFAKTHGLKCYPSQTNFVLIDFKRPADELFQALLEKGYIVRSGNALG FPTSLRITIGTKEQNEEILAILAEIL*" gene complement(2236013..2237095) /gene="hisC" /locus_tag="BSU_22620" /old_locus_tag="BSU22620" CDS complement(2237106..2237909) /gene="trpA" /locus_tag="BSU_22630" /old_locus_tag="BSU22630" /EC_number="4.2.1.20" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:2422155, 9383185, 10714985, 12963367, 17114058, 17555270" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 2422155, 9383185, 10714985, 12963367, 17114058, 17555270; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="tryptophan synthase (alpha subunit)" /protein_id="NP_390144.1" /db_xref="EnsemblGenomes-Gn:BSU22630" /db_xref="EnsemblGenomes-Tr:CAB14179" /db_xref="GOA:P07601" /db_xref="InterPro:IPR002028" /db_xref="InterPro:IPR011060" /db_xref="InterPro:IPR013785" /db_xref="InterPro:IPR018204" /db_xref="SubtiList:BG10291" /db_xref="UniProtKB/Swiss-Prot:P07601" /translation="MFKLDLQPSEKLFIPFITAGDPVPEVSIELAKSLQKAGATALEL GVAYSDPLADGPVIQRASKRALDQGMNIVKAIELGGEMKKNGVNIPIILFTYYNPVLQ LNKEYFFALLRENHIDGLLVPDLPLEESNSLQEECKSHEVTYISLVAPTSESRLKTII EQAEGFVYCVSSLGVTGVRNEFNSSVYPFIRTVKNLSTVPVAVGFGISNREQVIKMNE ISDGVVVGSALVRKIEELKDRLISAETRNQALQEFEDYAMAFSGLYSLK*" gene complement(2237106..2237909) /gene="trpA" /locus_tag="BSU_22630" /old_locus_tag="BSU22630" promotor_-10 complement(2237594..2237613) /Source="Nicolas_upshift_promotors" /id="U1770" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.598401598401598" /psig=1 /xcortree=3019 /SigmaFactorBS="gagaaatgaaaaaaaacggagtgaatattccgattatccTCT TTACGtattataatccTGTGTTACAATTGAACAAAGaatactttttcgctttactgcg g" /listShort="hisC, tyrA, aroE, S856, S855, ypiA" /listLong="ypiB, ypiF, qcrA, qcrB, qcrC" /label="promotor_-10" upshifts complement(2237611) /Source="Nicolas_upshifts" /id="U1770" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.598401598401598" /psig=1 /xcortree=3019 /SigmaFactorBS="gagaaatgaaaaaaaacggagtgaatattccgattatccTCT TTACGtattataatccTGTGTTACAATTGAACAAAGaatactttttcgctttactgcg g" /listShort="hisC, tyrA, aroE, S856, S855, ypiA" /listLong="ypiB, ypiF, qcrA, qcrB, qcrC" promotor_-35 complement(2237625..2237632) /Source="Nicolas_upshift_promotors" /id="U1770" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.598401598401598" /psig=1 /xcortree=3019 /SigmaFactorBS="gagaaatgaaaaaaaacggagtgaatattccgattatccTCT TTACGtattataatccTGTGTTACAATTGAACAAAGaatactttttcgctttactgcg g" /listShort="hisC, tyrA, aroE, S856, S855, ypiA" /listLong="ypiB, ypiF, qcrA, qcrB, qcrC" /label="promotor_-35" CDS complement(2237902..2239104) /gene="trpB" /locus_tag="BSU_22640" /old_locus_tag="BSU22640" /EC_number="4.2.1.20" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:2422155, 3062311, 9383185, 10714985, 12963367, 17114058, 17555270" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 2422155, 3062311, 9383185, 10714985, 12963367, 17114058, 17555270; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="tryptophan synthase (beta subunit)" /protein_id="NP_390145.2" /db_xref="EnsemblGenomes-Gn:BSU22640" /db_xref="EnsemblGenomes-Tr:CAB14180" /db_xref="GOA:P07600" /db_xref="InterPro:IPR001926" /db_xref="InterPro:IPR006653" /db_xref="InterPro:IPR006654" /db_xref="InterPro:IPR023026" /db_xref="InterPro:IPR036052" /db_xref="SubtiList:BG10290" /db_xref="UniProtKB/Swiss-Prot:P07600" /translation="MYPYPNEIGRYGDFGGKFVPETLMQPLDEIQTAFKQIKDDPAFR EEYYKLLKDYSGRPTALTYADRVTEYLGGAKIYLKREDLNHTGSHKINNALGQALLAK KMGKTKIIAETGAGQHGVAAATVAAKFGFSCTVFMGEEDVARQSLNVFRMKLLGAEVV PVTSGNGTLKDATNEAIRYWVQHCEDHFYMIGSVVGPHPYPQVVREFQKMIGEEAKDQ LKRIEGTMPDKVVACVGGGSNAMGMFQAFLNEDVELIGAEAAGKGIDTPLHAATISKG TVGVIHGSLTYLIQDEFGQIIEPYSISAGLDYPGIGPEHAYLHKSGRVTYDSITDEEA VDALKLLSEKEGILPAIESAHALAKAFKLAKGMDRGQLILVCLSGRGDKDVNTLMNVL EEEVKAHV*" gene complement(2237902..2239104) /gene="trpB" /locus_tag="BSU_22640" /old_locus_tag="BSU22640" CDS complement(2239085..2239732) /gene="trpF" /locus_tag="BSU_22650" /old_locus_tag="BSU22650" /EC_number="5.3.1.24" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:2422155, 9383185, 10714985, 12963367, 17114058" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 2422155, 9383185, 10714985, 12963367, 17114058; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="phosphoribosylanthranilate isomerase" /protein_id="NP_390146.3" /db_xref="EnsemblGenomes-Gn:BSU22650" /db_xref="EnsemblGenomes-Tr:CAB14181" /db_xref="GOA:P20167" /db_xref="InterPro:IPR001240" /db_xref="InterPro:IPR011060" /db_xref="InterPro:IPR013785" /db_xref="SubtiList:BG10289" /db_xref="UniProtKB/Swiss-Prot:P20167" /translation="MKKPALKYCGIRSLKDLQLAAESQADYLGFIFAESKRKVSPEDV KKWLNQVRVEKQVAGVFVNESIETMSRIAKSLKLDVIQLHGDEKPADAAALRKLTGCE IWKALHHQDNTTQEIARFKDNVDGFVIDSSVKGSRGGTGVAFSWECVPEYQQAAIGKR CFIAGGVNPDSITRLLKWQPEGIDLASGIEKNGQKDQNLMRLLEERMNRYVSISE*" gene complement(2239085..2239732) /gene="trpF" /locus_tag="BSU_22650" /old_locus_tag="BSU22650" downshifts complement(2239179) /Source="Nicolas_upshifts" /id="D1182" /incds=1 /nref=30 /ntot=83 /MaxReadThrough="8.17917" /MaxDrop="5.75867" /score="2.96963632" /energy="-11.9" /TU="U1771,U1772,U1773,U1775" /idTUdmin="U1774" /TUdmin=616 /isTUend="FALSE" misc_feature complement(2239355..2239358) /Source="Nicolas_upshift_promotors" /id="U1771" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.394605394605395" /psig="0.041958041958042" /xcortree=2849 /SigmaFactorBS="gcttcaccatcaagataacacaactcaagaaatagcccgctt taaagataatgttgaCGGCtttgtgattgattcatctgtaaaagggtctagaggcgga a" /listShort="trpB, trpA" /listLong="hisC, tyrA, aroE, S856, S855, ypiA, ypiB, ypiF" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(2239355) /Source="Nicolas_upshifts" /id="U1771" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.394605394605395" /psig="0.041958041958042" /xcortree=2849 /SigmaFactorBS="gcttcaccatcaagataacacaactcaagaaatagcccgctt taaagataatgttgaCGGCtttgtgattgattcatctgtaaaagggtctagaggcgga a" /listShort="trpB, trpA" /listLong="hisC, tyrA, aroE, S856, S855, ypiA, ypiB, ypiF" downshifts complement(2239575) /Source="Nicolas_upshifts" /id="D1183" /incds=1 /nref=1 /ntot=84 /MaxReadThrough="8.55417" /MaxDrop="3.4408" /score="2.96963632" /energy="-11.9" /TU="U1772,U1773,U1775" /idTUdmin="U1774" /TUdmin=220 /isTUend="FALSE" CDS complement(2239737..2240486) /gene="trpC" /locus_tag="BSU_22660" /old_locus_tag="BSU22660" /EC_number="4.1.1.48" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:2422155, 9383185, 17555270, 10627030, 10714985, 12963367, 17114058" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 2422155, 9383185, 17555270, 10627030, 10714985, 12963367, 17114058; Product type e: enzyme" /pseudo /codon_start=1 /transl_table=11 /product="indole-3-glycerol phosphate synthase" /db_xref="GOA:P03964" /db_xref="InterPro:IPR001468" /db_xref="InterPro:IPR011060" /db_xref="InterPro:IPR013785" /db_xref="InterPro:IPR013798" /db_xref="PSEUDO:CAB14182.3" /db_xref="SubtiList:BG11038" /db_xref="UniProtKB/Swiss-Prot:P03964" /translation="MLEKIIKQKKEEVKTLVLPVEQPFEKRSFKEALASPNRFIGLIA EVKKASPSKGLIKEDFVPVQIAKDYEAAKADAISVLTDTPFFQGENSYLSDVKRAVSI PVLRKDFIDSLQVEESRRIGADAILLIGEVLDPLHLHELYLEAGEKGMDVLVEVHDAS TLEQILKVFTPDILGVNNRNLKTFETSVKQTEQIASLVPKESLLVSESGIGSLEHLTF VNEHGARAVLIGESLMRQTSQRKAIHALFRE*" gene complement(2239737..2240486) /gene="trpC" /locus_tag="BSU_22660" /old_locus_tag="BSU22660" /pseudo misc_feature complement(2239770..2239772) /Source="Nicolas_upshift_promotors" /id="U1772" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.43956043956044" /psig="0.046953046953047" /xcortree=2850 /SigmaFactorBS="tgtcaatgaacatggggcgcgagctgtacttatcggtgaatc attgatgagacaaacttctCAGcgtaaagcaatccatgctttgtttagggagtgaggt t" /listShort="trpF, trpB, trpA, hisC, tyrA, aroE, S856" /listLong="S855, ypiA, ypiB, ypiF, qcrA, qcrB" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(2239773) /Source="Nicolas_upshifts" /id="U1772" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.43956043956044" /psig="0.046953046953047" /xcortree=2850 /SigmaFactorBS="tgtcaatgaacatggggcgcgagctgtacttatcggtgaatc attgatgagacaaacttctCAGcgtaaagcaatccatgctttgtttagggagtgaggt t" /listShort="trpF, trpB, trpA, hisC, tyrA, aroE, S856" /listLong="S855, ypiA, ypiB, ypiF, qcrA, qcrB" CDS complement(2240479..2241495) /gene="trpD" /locus_tag="BSU_22670" /old_locus_tag="BSU22670" /EC_number="2.4.2.18" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:2422155, 9383185, 17555270, 10714985, 12963367, 17114058" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 2422155, 9383185, 17555270, 10714985, 12963367, 17114058; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="anthranilate phosphoribosyltransferase" /protein_id="NP_390148.2" /db_xref="EnsemblGenomes-Gn:BSU22670" /db_xref="EnsemblGenomes-Tr:CAB14183" /db_xref="GOA:P03947" /db_xref="InterPro:IPR000312" /db_xref="InterPro:IPR005940" /db_xref="InterPro:IPR017459" /db_xref="InterPro:IPR035902" /db_xref="InterPro:IPR036320" /db_xref="SubtiList:BG10288" /db_xref="UniProtKB/Swiss-Prot:P03947" /translation="MNRFLQLCVDGKTLTAGEAETLMNMMMAAEMTPSEMGGILSILA HRGETPEELAGFVKAMRAHALTVDGLPDIVDTCGTGGDGISTFNISTASAIVASAAGA KIAKHGNRSVSSKSGSADVLEELEVSIQTTPEKVKSSIETNNMGFLFAPLYHSSMKHV AGTRKELGFRTVFNLLGPLSNPLQAKRQVIGVYSVEKAGLMASALETFQPKHVMFVSS RDGLDELSITAPTDVIELKDGERREYTVSPEDFGFTNGRLEDLQVQSPKESAYLIQNI FENKSSSSALSITAFNAGAAIYTAGITASLKEGTELALETITSGGAAAQLERLKQKEE EIYA*" gene complement(2240479..2241495) /gene="trpD" /locus_tag="BSU_22670" /old_locus_tag="BSU22670" CDS complement(2241467..2243014) /gene="trpE" /locus_tag="BSU_22680" /old_locus_tag="BSU22680" /EC_number="4.1.3.27" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:2422155, 9383185, 17555270, 10714985, 12963367, 15063849, 17114058" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 2422155, 9383185, 17555270, 10714985, 12963367, 15063849, 17114058; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="anthranilate synthase" /protein_id="NP_390149.1" /db_xref="EnsemblGenomes-Gn:BSU22680" /db_xref="EnsemblGenomes-Tr:CAB14184" /db_xref="GOA:P03963" /db_xref="InterPro:IPR005256" /db_xref="InterPro:IPR005801" /db_xref="InterPro:IPR006805" /db_xref="InterPro:IPR015890" /db_xref="InterPro:IPR019999" /db_xref="SubtiList:BG10287" /db_xref="UniProtKB/Swiss-Prot:P03963" /translation="MNFQSNISAFLEDSLSHHTIPIVETFTVDTLTPIQMIEKLDREI TYLLESKDDTSTWSRYSFIGLNPFLTIKEEQGRFSAADQDSKSLYTGNELKEVLNWMN TTYKIKTPELGIPFVGGAVGYLSYDMIPLIEPSVPSHTKETDMEKCMLFVCRTLIAYD HETKNVHFIQYARLTGEETKNEKMDVFHQNHLELQNLIEKMMDQKNIKELFLSADSYK TPSFETVSSNYEKSAFMADVEKIKSYIKAGDIFQGVLSQKFEVPIKADAFELYRVLRI VNPSPYMYYMKLLDREIVGSSPERLIHVQDGHLEIHPIAGTRKRGADKAEDERLKVEL MKDEKEKAEHYMLVDLARNDIGRVAEYGSVSVPEFTKIVSFSHVMHIISVVTGRLKKG VHPVDALMSAFPAGTLTGAPKIRAMQLLQELEPTPRETYGGCIAYIGFDGNIDSCITI RTMSVKNGVASIQAGAGIVADSVPEAEYEESCNKAGALLKTIHIAEDMFHSKEDKADE QISTIVR*" gene complement(2241467..2243014) /gene="trpE" /locus_tag="BSU_22680" /old_locus_tag="BSU22680" S_feature complement(2243093..2243224) /Source="Nicolas_S_feature" /locus_tag="new_2377495_2377626_c" /HighExp="Etha, S1, GM 25, GM 15, HiTm, Glu, MG-0.1, GM 60, M9-exp, GM 120" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigWXY, SigA, SigA, SigA" /TUshortPSig="0.994, 0.647, 0.999, 1, 0.996" /TUlongSig="SigA, SigA, SigA" /TUlongPSig="0.999, 1, 0.998" /label="S857" downshifts complement(2243136) /Source="Nicolas_upshifts" /id="D1184" /incds=0 /nref=61 /ntot=157 /MaxReadThrough="7.41666" /MaxDrop="5.25158" /score="2.96963632" /energy="-11.9" /TU="U1773,U1774,U1775,U1776" /idTUdmin="U1777" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(2243215..2243234) /Source="Nicolas_upshift_promotors" /id="U1773" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.52047952047952" /psig="0.994005994005994" /xcortree=401 /SigmaFactorBS="aaaagttgtcgtattgaggcccgatttaTCATTGACaaaaaa tactgaatTGTAATACGATAAGAACAGCttagaaatacacaagagtgtgtataaagca a" /listShort="S857, trpE, trpD, trpC, trpF, trpB, trpA, hisC, tyrA, aroE, S856" /listLong="S855, ypiA, ypiB, ypiF, qcrA, qcrB" /label="promotor_-10" upshifts complement(2243224) /Source="Nicolas_upshifts" /id="U1773" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.52047952047952" /psig="0.994005994005994" /xcortree=401 /SigmaFactorBS="aaaagttgtcgtattgaggcccgatttaTCATTGACaaaaaa tactgaatTGTAATACGATAAGAACAGCttagaaatacacaagagtgtgtataaagca a" /listShort="S857, trpE, trpD, trpC, trpF, trpB, trpA, hisC, tyrA, aroE, S856" /listLong="S855, ypiA, ypiB, ypiF, qcrA, qcrB" CDS complement(2243230..2243613) /gene="aroH" /locus_tag="BSU_22690" /old_locus_tag="BSU22690" /EC_number="5.4.99.5" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:2105742, 8378335, 9384560, 10818343, 15865424, 16060652, 28743924" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 2105742, 8378335, 9384560, 10818343, 15865424, 16060652, 28743924; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="chorismate mutase" /protein_id="NP_390150.1" /db_xref="EnsemblGenomes-Gn:BSU22690" /db_xref="EnsemblGenomes-Tr:CAB14185" /db_xref="GOA:P19080" /db_xref="InterPro:IPR008243" /db_xref="InterPro:IPR035959" /db_xref="PDB:1COM" /db_xref="PDB:1DBF" /db_xref="PDB:1FNJ" /db_xref="PDB:1FNK" /db_xref="PDB:2CHS" /db_xref="PDB:2CHT" /db_xref="PDB:3ZO8" /db_xref="PDB:3ZOP" /db_xref="PDB:3ZP4" /db_xref="PDB:3ZP7" /db_xref="SubtiList:BG10286" /db_xref="UniProtKB/Swiss-Prot:P19080" /translation="MMIRGIRGATTVERDTEEEILQKTKQLLEKIIEENHTKPEDVVQ MLLSATPDLHAVFPAKAVRELSGWQYVPVTCMQEMDVTGGLKKCIRVMMTVQTDVPQD QIRHVYLEKVVVLRPDLSLTKNTEL*" gene complement(2243230..2243613) /gene="aroH" /locus_tag="BSU_22690" /old_locus_tag="BSU22690" promotor_-35 complement(2243249..2243256) /Source="Nicolas_upshift_promotors" /id="U1773" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.52047952047952" /psig="0.994005994005994" /xcortree=401 /SigmaFactorBS="aaaagttgtcgtattgaggcccgatttaTCATTGACaaaaaa tactgaatTGTAATACGATAAGAACAGCttagaaatacacaagagtgtgtataaagca a" /listShort="S857, trpE, trpD, trpC, trpF, trpB, trpA, hisC, tyrA, aroE, S856" /listLong="S855, ypiA, ypiB, ypiF, qcrA, qcrB" /label="promotor_-35" CDS complement(2243610..2244698) /gene="aroB" /locus_tag="BSU_22700" /old_locus_tag="BSU22700" /EC_number="4.2.3.4" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:97285, 97286, 6795181, 24628944" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 97285, 97286, 6795181, 24628944; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="3-dehydroquinate synthase" /protein_id="NP_390151.1" /db_xref="EnsemblGenomes-Gn:BSU22700" /db_xref="EnsemblGenomes-Tr:CAB14186" /db_xref="GOA:P31102" /db_xref="InterPro:IPR016037" /db_xref="InterPro:IPR030960" /db_xref="InterPro:IPR030963" /db_xref="SubtiList:BG10285" /db_xref="UniProtKB/Swiss-Prot:P31102" /translation="MKTLHVQTASSSYPVFIGQGIRKKACELLTSLNRPLTRIMFVTD EEVDRLYGDEMLHLLQEKWPVKKVTVPSGEQAKSMDMYTKLQSEAIRFHMDRSSCIIA FGGGVVGDLAGFVAATFMRGIDFIQMPTTLLAHDSAVGGKVAVNHPLGKNLIGAFYQP KAVLYDTDFLRSLPEKELRSGMAEVIKHAFIYDRAFLEELLNIHSLRDITNDQLNDMI FKGISIKASVVQQDEKEEGIRAYLNFGHTLGHAVEAEYGYGQITHGDAVALGMQFALY ISEKTVGCEMDRKRLVSWLKSLGYPSQIRKETETSVLLNRMMNDKKTRGGKIQFIVLN ELGKVADHTFSRNELESWLNKWRLEETS*" gene complement(2243610..2244698) /gene="aroB" /locus_tag="BSU_22700" /old_locus_tag="BSU22700" promotor_-10 complement(2243739..2243754) /Source="Nicolas_upshift_promotors" /id="U1774" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp="0.647352647352647" /psig="0.647352647352647" /xcortree=1460 /SigmaFactorBS="aaagcctgggttatccaagtcaaatcagaaaagagacGGAAA CTTCggttctcttgaaCCGTATGATGAATGATaagaaaacccgtggcgggaagattca g" /listShort="aroH, S857, trpE, trpD, trpC" /listLong="trpF, trpB, trpA, hisC, tyrA, aroE" /label="promotor_-10" upshifts complement(2243752) /Source="Nicolas_upshifts" /id="U1774" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp="0.647352647352647" /psig="0.647352647352647" /xcortree=1460 /SigmaFactorBS="aaagcctgggttatccaagtcaaatcagaaaagagacGGAAA CTTCggttctcttgaaCCGTATGATGAATGATaagaaaacccgtggcgggaagattca g" /listShort="aroH, S857, trpE, trpD, trpC" /listLong="trpF, trpB, trpA, hisC, tyrA, aroE" promotor_-35 complement(2243767..2243775) /Source="Nicolas_upshift_promotors" /id="U1774" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp="0.647352647352647" /psig="0.647352647352647" /xcortree=1460 /SigmaFactorBS="aaagcctgggttatccaagtcaaatcagaaaagagacGGAAA CTTCggttctcttgaaCCGTATGATGAATGATaagaaaacccgtggcgggaagattca g" /listShort="aroH, S857, trpE, trpD, trpC" /listLong="trpF, trpB, trpA, hisC, tyrA, aroE" /label="promotor_-35" CDS complement(2244698..2245870) /gene="aroF" /locus_tag="BSU_22710" /old_locus_tag="BSU22710" /EC_number="4.2.3.5" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:97285, 97286, 6795181, 10518299, 24628944" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 97285, 97286, 6795181, 10518299, 24628944; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="chorismate synthase" /protein_id="NP_390152.3" /db_xref="EnsemblGenomes-Gn:BSU22710" /db_xref="EnsemblGenomes-Tr:CAB14187" /db_xref="GOA:P31104" /db_xref="InterPro:IPR000453" /db_xref="InterPro:IPR020541" /db_xref="InterPro:IPR035904" /db_xref="SubtiList:BG10284" /db_xref="UniProtKB/Swiss-Prot:P31104" /translation="MRYLTAGESHGPQLTTIIEGVPAGLYITEEDINFELARRQKGHG RGRRMQIEKDQAKIMSGVRHARTLGSPIALVVENNDWKHWTKIMGAAPITEDEEKEMK RQISRPRPGHADLNGAIKYNHRDMRNVLERSSARETTVRVAAGAVAKKILSELGIKVA GHVLQIGAVKAEKTEYTSIEDLQRVTEESPVRCYDEEAGKKMMAAIDEAKANGDSIGG IVEVIVEGMPVGVGSYVHYDRKLDSKLAAAVLSINAFKGVEFGIGFEAAGRNGSEVHD EIIWDEEKGYTRATNRLGGLEGGMTTGMPIVVRGVMKPIPTLYKPLKSVDIETKEPFS ASIERSDSCAVPAASVVAEAAVAWEIANAVVEQFGLDQIDRIRENVENMRKLSREF*" gene complement(2244698..2245870) /gene="aroF" /locus_tag="BSU_22710" /old_locus_tag="BSU22710" promotor_-10 complement(2245905..2245924) /Source="Nicolas_upshift_promotors" /id="U1775" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.607392607392607" /psig="0.999000999001" /xcortree=3020 /SigmaFactorBS="tagtcccagccgatacattcttttatcaaaaaagatagACTG ACTTtttgctgaaaaaTATGTTATAGTAGTCTTACTtaaaagcgttaatgcgatgaag g" /listShort="aroF, aroB, aroH, S857, trpE, trpD, trpC, trpF, trpB, trpA, hisC, tyrA, aroE" /listLong="S856, S855, ypiA, ypiB, ypiF" /label="promotor_-10" upshifts complement(2245922) /Source="Nicolas_upshifts" /id="U1775" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.607392607392607" /psig="0.999000999001" /xcortree=3020 /SigmaFactorBS="tagtcccagccgatacattcttttatcaaaaaagatagACTG ACTTtttgctgaaaaaTATGTTATAGTAGTCTTACTtaaaagcgttaatgcgatgaag g" /listShort="aroF, aroB, aroH, S857, trpE, trpD, trpC, trpF, trpB, trpA, hisC, tyrA, aroE" /listLong="S856, S855, ypiA, ypiB, ypiF" promotor_-35 complement(2245937..2245944) /Source="Nicolas_upshift_promotors" /id="U1775" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.607392607392607" /psig="0.999000999001" /xcortree=3020 /SigmaFactorBS="tagtcccagccgatacattcttttatcaaaaaagatagACTG ACTTtttgctgaaaaaTATGTTATAGTAGTCTTACTtaaaagcgttaatgcgatgaag g" /listShort="aroF, aroB, aroH, S857, trpE, trpD, trpC, trpF, trpB, trpA, hisC, tyrA, aroE" /listLong="S856, S855, ypiA, ypiB, ypiF" /label="promotor_-35" CDS complement(2245945..2246715) /gene="cheR" /locus_tag="BSU_22720" /old_locus_tag="BSU22720" /EC_number="2.1.1.80" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:7635819, 7893679, 8244966, 10196193, 15544802, 25799883, 27544050" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7635819, 7893679, 8244966, 10196193, 15544802, 25799883, 27544050; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="methyl-accepting chemotaxis proteins (MCPs) methyltransferase" /protein_id="NP_390153.2" /db_xref="EnsemblGenomes-Gn:BSU22720" /db_xref="EnsemblGenomes-Tr:CAB14188" /db_xref="GOA:P31105" /db_xref="InterPro:IPR000780" /db_xref="InterPro:IPR022641" /db_xref="InterPro:IPR022642" /db_xref="InterPro:IPR029063" /db_xref="InterPro:IPR036804" /db_xref="PDB:5FTW" /db_xref="SubtiList:BG10283" /db_xref="UniProtKB/Swiss-Prot:P31105" /translation="MDTYSVFTTKWKQLTGVDLTLYKEAQMKRRLTSLYEKKGFQSFK DFAAALEKDQALLNETLDRMTINVSEFYRNYKRWEVLETAILPLIKTSRPLKIWSAAC STGEEPYTLAMLLDQQKGLPGYQILATDIDEKALEKAKKGVYQERSLQEVPLSVKDRY FTQNANRSYEVKTEIKKNITFKKHNLLADRYEQDFDLIVCRNVFIYFTESAKEELYLK MAHSLKKNGVLFVGSTEQIFNPEKFGLVPADTFFYQKR*" gene complement(2245945..2246715) /gene="cheR" /locus_tag="BSU_22720" /old_locus_tag="BSU22720" promotor_-10 complement(2246741..2246760) /Source="Nicolas_upshift_promotors" /id="U1776" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.821178821178821" /psig=1 /xcortree=3061 /SigmaFactorBS="tctaaaatcagctgaaaagctgatttttttattgaaacaaTA CAATTtcctgataaaaCAAGCTATACTAGGACAAAAagacagcgagactgggagagta g" /listShort="cheR, aroF, aroB, aroH, S857, trpE, trpD" /listLong="trpC, trpF, trpB, trpA, hisC, tyrA, aroE, S856, S855, ypiA, ypiB, ypiF" /label="promotor_-10" upshifts complement(2246758) /Source="Nicolas_upshifts" /id="U1776" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.821178821178821" /psig=1 /xcortree=3061 /SigmaFactorBS="tctaaaatcagctgaaaagctgatttttttattgaaacaaTA CAATTtcctgataaaaCAAGCTATACTAGGACAAAAagacagcgagactgggagagta g" /listShort="cheR, aroF, aroB, aroH, S857, trpE, trpD" /listLong="trpC, trpF, trpB, trpA, hisC, tyrA, aroE, S856, S855, ypiA, ypiB, ypiF" promotor_-35 complement(2246772..2246778) /Source="Nicolas_upshift_promotors" /id="U1776" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.821178821178821" /psig=1 /xcortree=3061 /SigmaFactorBS="tctaaaatcagctgaaaagctgatttttttattgaaacaaTA CAATTtcctgataaaaCAAGCTATACTAGGACAAAAagacagcgagactgggagagta g" /listShort="cheR, aroF, aroB, aroH, S857, trpE, trpD" /listLong="trpC, trpF, trpB, trpA, hisC, tyrA, aroE, S856, S855, ypiA, ypiB, ypiF" /label="promotor_-35" S_feature complement(2246790..2246951) /Source="Nicolas_S_feature" /locus_tag="new_2381192_2381353_c" /HighExp="M0t90, Lbstat, S0, Mt0, M0t45, M40t90, Lbtran, Mal, G/S, MG-0.2" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA, SigA, SigA" /TUshortPSig="0.996, 0.999, 1, 0.998" /TUlongSig="SigEF" /TUlongPSig=1 /label="S858" downshifts complement(2246833) /Source="Nicolas_upshifts" /id="D1185" /incds=0 /nref=26 /ntot=128 /MaxReadThrough="4.04342" /MaxDrop="4.7493" /score="29.2259705" /energy="-8.6" /TU="U1777,U1778,U1779,U1780" /idTUdmin="U1778" /TUdmin="-880" /isTUend="FALSE" CDS complement(2246952..2247401) /gene="ndk" /locus_tag="BSU_22730" /old_locus_tag="BSU22730" /EC_number="2.7.4.6" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 9179491, 11734624, 22720735, 26735940; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="nucleoside diphosphate kinase" /protein_id="NP_390154.1" /db_xref="EnsemblGenomes-Gn:BSU22730" /db_xref="EnsemblGenomes-Tr:CAB14189" /db_xref="GOA:P31103" /db_xref="InterPro:IPR001564" /db_xref="InterPro:IPR023005" /db_xref="InterPro:IPR034907" /db_xref="InterPro:IPR036850" /db_xref="SubtiList:BG10282" /db_xref="UniProtKB/Swiss-Prot:P31103" /translation="MMEKTFIMVKPDGVQRQLIGDILSRFERKGLQLAGAKLMRVTEQ MAEKHYAEHQGKPFFGELVEFITSGPVFAMVWEGENVIEVTRQLIGKTNPKEALPGTI RGDYGMFVGKNIIHGSDSLESAEREINIFFKNEELVSYQQLMAGWIY*" gene complement(2246952..2247401) /gene="ndk" /locus_tag="BSU_22730" /old_locus_tag="BSU22730" promotor_-10 complement(2247444..2247463) /Source="Nicolas_upshift_promotors" /id="U1777" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.578421578421578" /psig="0.996003996003996" /xcortree=1593 /SigmaFactorBS="gtagatattaagaaatttctccgccccgGATTGATTaattat cagaaaGATGTTACGATTTCGGTGTGcagtgtgaaagcctatacatacataatgatgg g" /listShort="ndk, S858, cheR, aroF, aroB, aroH, S857" /listLong="trpE, trpD, trpC, trpF, trpB, trpA, hisC, tyrA, aroE" /label="promotor_-10" upshifts complement(2247451) /Source="Nicolas_upshifts" /id="U1777" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.578421578421578" /psig="0.996003996003996" /xcortree=1593 /SigmaFactorBS="gtagatattaagaaatttctccgccccgGATTGATTaattat cagaaaGATGTTACGATTTCGGTGTGcagtgtgaaagcctatacatacataatgatgg g" /listShort="ndk, S858, cheR, aroF, aroB, aroH, S857" /listLong="trpE, trpD, trpC, trpF, trpB, trpA, hisC, tyrA, aroE" promotor_-35 complement(2247476..2247483) /Source="Nicolas_upshift_promotors" /id="U1777" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.578421578421578" /psig="0.996003996003996" /xcortree=1593 /SigmaFactorBS="gtagatattaagaaatttctccgccccgGATTGATTaattat cagaaaGATGTTACGATTTCGGTGTGcagtgtgaaagcctatacatacataatgatgg g" /listShort="ndk, S858, cheR, aroF, aroB, aroH, S857" /listLong="trpE, trpD, trpC, trpF, trpB, trpA, hisC, tyrA, aroE" /label="promotor_-35" CDS complement(2247517..2248563) /gene="hepT" /locus_tag="BSU_22740" /old_locus_tag="BSU22740" /EC_number="2.5.1.30" /function="16.10: Respire" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:6768722, 9139683, 9720033, 9756625, 10545188, 23840410" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 6768722, 9139683, 9720033, 9756625, 10545188, 23840410; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="heptaprenyl diphosphate synthase component II" /protein_id="NP_390155.1" /db_xref="EnsemblGenomes-Gn:BSU22740" /db_xref="EnsemblGenomes-Tr:CAB14190" /db_xref="GOA:P31114" /db_xref="InterPro:IPR000092" /db_xref="InterPro:IPR008949" /db_xref="InterPro:IPR014119" /db_xref="InterPro:IPR033749" /db_xref="SubtiList:BG10281" /db_xref="UniProtKB/Swiss-Prot:P31114" /translation="MLNIIRLLAESLPRISDGNENTDVWVNDMKFKMAYSFLNDDIDV IERELEQTVRSDYPLLSEAGLHLLQAGGKRIRPVFVLLSGMFGDYDINKIKYVAVTLE MIHMASLVHDDVIDDAELRRGKPTIKAKWDNRIAMYTGDYMLAGSLEMMTRINEPKAH RILSQTIVEVCLGEIEQIKDKYNMEQNLRTYLRRIKRKTALLIAVSCQLGAIASGADE KIHKALYWFGYYVGMSYQIIDDILDFTSTEEELGKPVGGDLLQGNVTLPVLYALKNPA LKNQLKLINSETTQEQLEPIIEEIKKTDAIEASMAVSEMYLQKAFQKLNTLPRGRARS SLAAIAKYIGKRKF*" gene complement(2247517..2248563) /gene="hepT" /locus_tag="BSU_22740" /old_locus_tag="BSU22740" CDS complement(2248505..2249206) /gene="menG" /locus_tag="BSU_22750" /old_locus_tag="BSU22750" /EC_number="2.1.1.163" /function="16.10: Respire" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:16279806, 9045837, 9139683, 21513522, 26735940" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16279806, 9045837, 9139683, 21513522, 26735940; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="demethylmenaquinone methyltransferase" /protein_id="NP_390156.1" /db_xref="EnsemblGenomes-Gn:BSU22750" /db_xref="EnsemblGenomes-Tr:CAB14191" /db_xref="GOA:P31113" /db_xref="InterPro:IPR004033" /db_xref="InterPro:IPR014122" /db_xref="InterPro:IPR023576" /db_xref="InterPro:IPR029063" /db_xref="SubtiList:BG10280" /db_xref="UniProtKB/Swiss-Prot:P31113" /translation="MQDSKEQRVHGVFEKIYKNYDQMNSVISFQQHKKWRDKTMRIMN VKEGAKALDVCCGTADWTIALAKAAGKSGEIKGLDFSENMLSVGEQKVKDGGFSQIEL LHGNAMELPFDDDTFDYVTIGFGLRNVPDYLTVLKEMRRVVKPGGQVVCLETSQPEMF GFRQAYFMYFKYIMPFFGKLFAKSYKEYSWLQESARDFPGMKELAGLFEEAGLKNVKY HSFTGGVAATHIGWK*" gene complement(2248505..2249206) /gene="menG" /locus_tag="BSU_22750" /old_locus_tag="BSU22750" CDS complement(2249213..2249968) /gene="hepS" /locus_tag="BSU_22760" /old_locus_tag="BSU22760" /EC_number="2.5.1.30" /function="16.2: Construct biomass (Anabolism)" /function="16.10: Respire" /experiment="publication(s) with functional evidences, PMID:6768722, 9139683, 9720033, 9756625, 10545188, 23840410" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 6768722, 9139683, 9720033, 9756625, 10545188, 23840410; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="heptaprenyl diphosphate synthase component I" /protein_id="NP_390157.1" /db_xref="EnsemblGenomes-Gn:BSU22760" /db_xref="EnsemblGenomes-Tr:CAB14192" /db_xref="GOA:P31112" /db_xref="InterPro:IPR009920" /db_xref="SubtiList:BG10279" /db_xref="UniProtKB/Swiss-Prot:P31112" /translation="MQDIYGTLANLNTKLKQKLSHPYLAKHISAPKIDEDKLLLFHAL FEEADIKNNDRENYIVTAMLVQSALDTHDEVTTARVIKRDENKNRQLTVLAGDYFSGL YYSLLSEMKDIYMIRTLATAIKEINEHKIRLYDRSFKDENDFFESVGIVESALFHRVA EHFNLPRWKKLSSDFFVFKRLMNGNDAFLDVIGSFIQLGKTKEEILEDCFKKAKNSIE SLLPLNSPIQNILINRLKTISQDQTYHQKVEEG*" gene complement(2249213..2249968) /gene="hepS" /locus_tag="BSU_22760" /old_locus_tag="BSU22760" S_feature complement(2249969..2250054) /Source="Nicolas_S_feature" /locus_tag="new_2384371_2384456_c" /HighExp="H2O2, G150, G180, Paraq, Oxctl, G135, T-4.40H, Lbexp, T-3.40H, dia0" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA, SigA" /TUshortPSig="0.999, 1, 0.998" /TUlongSig="SigEF" /TUlongPSig=1 /label="S859" promotor_-10 complement(2250043..2250062) /Source="Nicolas_upshift_promotors" /id="U1778" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.919080919080919" /psig="0.999000999001" /xcortree=2333 /SigmaFactorBS="ttaaaagcaaatgctcgcaaacagcgggaggataCAGCCAAT ttctttttttTATGCTATAATGATACCTGCgtaagcgaatgaaaagataaaactcata c" /listShort="S859, hepS, menH, hepT, ndk, S858, cheR" /listLong="aroF, aroB, aroH, S857, trpE, trpD, trpC, trpF, trpB, trpA, hisC, tyrA, aroE, S856, S855, ypiA, ypiB, ypiF" /label="promotor_-10" upshifts complement(2250054) /Source="Nicolas_upshifts" /id="U1778" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.919080919080919" /psig="0.999000999001" /xcortree=2333 /SigmaFactorBS="ttaaaagcaaatgctcgcaaacagcgggaggataCAGCCAAT ttctttttttTATGCTATAATGATACCTGCgtaagcgaatgaaaagataaaactcata c" /listShort="S859, hepS, menH, hepT, ndk, S858, cheR" /listLong="aroF, aroB, aroH, S857, trpE, trpD, trpC, trpF, trpB, trpA, hisC, tyrA, aroE, S856, S855, ypiA, ypiB, ypiF" promotor_-35 complement(2250073..2250080) /Source="Nicolas_upshift_promotors" /id="U1778" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.919080919080919" /psig="0.999000999001" /xcortree=2333 /SigmaFactorBS="ttaaaagcaaatgctcgcaaacagcgggaggataCAGCCAAT ttctttttttTATGCTATAATGATACCTGCgtaagcgaatgaaaagataaaactcata c" /listShort="S859, hepS, menH, hepT, ndk, S858, cheR" /listLong="aroF, aroB, aroH, S857, trpE, trpD, trpC, trpF, trpB, trpA, hisC, tyrA, aroE, S856, S855, ypiA, ypiB, ypiF" /label="promotor_-35" CDS complement(2250132..2250359) /gene="mtrB" /locus_tag="BSU_22770" /old_locus_tag="BSU22770" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:15099736, 15588817, 16285852, 16306262, 17114058, 28069823" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15099736, 15588817, 16285852, 16306262, 17114058, 28069823; Product type r : regulator" /codon_start=1 /transl_table=11 /product="tryptophan operon RNA-binding attenuation protein (TRAP)" /protein_id="NP_390158.1" /db_xref="EnsemblGenomes-Gn:BSU22770" /db_xref="EnsemblGenomes-Tr:CAB14193" /db_xref="GOA:P19466" /db_xref="InterPro:IPR000824" /db_xref="InterPro:IPR016031" /db_xref="InterPro:IPR023558" /db_xref="PDB:1WAP" /db_xref="PDB:3ZZQ" /db_xref="PDB:4B27" /db_xref="SubtiList:BG10278" /db_xref="UniProtKB/Swiss-Prot:P19466" /translation="MNQKHSSDFVVIKAVEDGVNVIGLTRGTDTKFHHSEKLDKGEVI IAQFTEHTSAIKVRGEALIQTAYGEMKSEKK*" gene complement(2250132..2250359) /gene="mtrB" /locus_tag="BSU_22770" /old_locus_tag="BSU22770" downshifts complement(2250153) /Source="Nicolas_upshifts" /id="D1186" /incds=0 /nref=22 /ntot=162 /MaxReadThrough="6.02348" /MaxDrop="4.385" /score="8.50521108" /energy="-10.5" /TU="U1779,U1780" /idTUdmin="U1781" /TUdmin=1499 /isTUend="FALSE" CDS complement(2250381..2250953) /gene="folEA" /locus_tag="BSU_22780" /old_locus_tag="BSU22780" /EC_number="3.5.4.16" /function="16.2: Construct biomass (Anabolism)" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:1551827, 12559918, 14717702, 17032654" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1551827, 12559918, 14717702, 17032654; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="GTP cyclohydrolase I" /protein_id="NP_390159.1" /db_xref="EnsemblGenomes-Gn:BSU22780" /db_xref="EnsemblGenomes-Tr:CAB14194" /db_xref="GOA:P19465" /db_xref="InterPro:IPR001474" /db_xref="InterPro:IPR018234" /db_xref="InterPro:IPR020602" /db_xref="SubtiList:BG10277" /db_xref="UniProtKB/Swiss-Prot:P19465" /translation="MKEVNKEQIEQAVRQILEAIGEDPNREGLLDTPKRVAKMYAEVF SGLNEDPKEHFQTIFGENHEELVLVKDIAFHSMCEHHLVPFYGKAHVAYIPRGGKVTG LSKLARAVEAVAKRPQLQERITSTIAESIVETLDPHGVMVVVEAEHMCMTMRGVRKPG AKTVTSAVRGVFKDDAAARAEVLEHIKRQD*" gene complement(2250381..2250953) /gene="folEA" /locus_tag="BSU_22780" /old_locus_tag="BSU22780" promotor_-10 complement(2250982..2251001) /Source="Nicolas_upshift_promotors" /id="U1779" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.841158841158841" /psig=1 /xcortree=1869 /SigmaFactorBS="aagagcatgggcttcctgacagggcattcactTTGCTTTtag cggggcataTGTGCTAGAATCGAAATTAAatgtattcattggtggaggacatagaaca t" /listShort="folEA, mtrB, S859, hepS, menH, hepT, ndk, S858, cheR" /listLong="aroF, aroB, aroH, S857, trpE, trpD, trpC, trpF, trpB, trpA, hisC, tyrA, aroE, S856, S855, ypiA, ypiB, ypiF" /label="promotor_-10" upshifts complement(2250992) /Source="Nicolas_upshifts" /id="U1779" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.841158841158841" /psig=1 /xcortree=1869 /SigmaFactorBS="aagagcatgggcttcctgacagggcattcactTTGCTTTtag cggggcataTGTGCTAGAATCGAAATTAAatgtattcattggtggaggacatagaaca t" /listShort="folEA, mtrB, S859, hepS, menH, hepT, ndk, S858, cheR" /listLong="aroF, aroB, aroH, S857, trpE, trpD, trpC, trpF, trpB, trpA, hisC, tyrA, aroE, S856, S855, ypiA, ypiB, ypiF" S_feature complement(2250994..2251077) /Source="Nicolas_S_feature" /locus_tag="new_2385396_2385479_c" /HighExp="Oxctl, G150, G180, G135, LBGexp, Paraq, LPh, H2O2, aero, Lbexp" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.998" /TUlongSig="SigEF" /TUlongPSig=1 /label="S860" promotor_-35 complement(2251014..2251020) /Source="Nicolas_upshift_promotors" /id="U1779" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.841158841158841" /psig=1 /xcortree=1869 /SigmaFactorBS="aagagcatgggcttcctgacagggcattcactTTGCTTTtag cggggcataTGTGCTAGAATCGAAATTAAatgtattcattggtggaggacatagaaca t" /listShort="folEA, mtrB, S859, hepS, menH, hepT, ndk, S858, cheR" /listLong="aroF, aroB, aroH, S857, trpE, trpD, trpC, trpF, trpB, trpA, hisC, tyrA, aroE, S856, S855, ypiA, ypiB, ypiF" /label="promotor_-35" downshifts complement(2251122) /Source="Nicolas_upshifts" /id="D1187" /incds=0 /nref=33 /ntot=254 /MaxReadThrough="6.68474" /MaxDrop="5.1938" /score="8.50521108" /energy="-10.5" /TU="U1780" /idTUdmin="U1781" /TUdmin=530 /isTUend="FALSE" CDS complement(2251141..2251419) /gene="hbs" /locus_tag="BSU_22790" /old_locus_tag="BSU22790" /function="16.1: Circulate" /function="16.3: Control" /function="16.6: Maintain" /function="16.9: Replicate" /experiment="publication(s) with functional evidences, PMID:1382620, 9106208, 10224127, 10231583, 10715001, 11931565, 19210617" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1382620, 9106208, 10224127, 10231583, 10715001, 11931565, 19210617; Product type f: factor" /codon_start=1 /transl_table=11 /product="non-specific DNA-binding protein HBsu" /protein_id="NP_390160.1" /db_xref="EnsemblGenomes-Gn:BSU22790" /db_xref="EnsemblGenomes-Tr:CAB14195" /db_xref="GOA:P08821" /db_xref="InterPro:IPR000119" /db_xref="InterPro:IPR010992" /db_xref="InterPro:IPR020816" /db_xref="SubtiList:BG10276" /db_xref="UniProtKB/Swiss-Prot:P08821" /translation="MNKTELINAVAEASELSKKDATKAVDSVFDTILDALKNGDKIQL IGFGNFEVRERSARKGRNPQTGEEIEIPASKVPAFKPGKALKDAVAGK*" gene complement(2251141..2251419) /gene="hbs" /locus_tag="BSU_22790" /old_locus_tag="BSU22790" S_feature complement(2251420..2251645) /Source="Nicolas_S_feature" /locus_tag="new_2385822_2386047_c" /HighExp="dia5, C90, T-0.40H, G/S, S1, Salt, Lbexp, dia15, T-1.40H, BI" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.998" /TUlongSig="SigEF" /TUlongPSig=1 /label="S861" promotor_-10 complement(2251627..2251646) /Source="Nicolas_upshift_promotors" /id="U1780" /multdbtbs="SigA" /comp="M17" /sig="SigA" /pcomp="0.591408591408591" /psig="0.998001998001998" /xcortree=2643 /SigmaFactorBS="aaaaaaggaatattcgttcggtaaatcaccttaaatcCTTGA CgagcaagggattgacgCTTTAAAATGCTTGATATGGctttttatatgtgttactcta c" /listShort="S861, hbs, S860, folEA, mtrB, S859, hepS, menH, hepT, ndk, S858, cheR" /listLong="aroF, aroB, aroH, S857, trpE, trpD, trpC, trpF, trpB, trpA, hisC, tyrA, aroE, S856, S855, ypiA, ypiB, ypiF" /label="promotor_-10" upshifts complement(2251645) /Source="Nicolas_upshifts" /id="U1780" /multdbtbs="SigA" /comp="M17" /sig="SigA" /pcomp="0.591408591408591" /psig="0.998001998001998" /xcortree=2643 /SigmaFactorBS="aaaaaaggaatattcgttcggtaaatcaccttaaatcCTTGA CgagcaagggattgacgCTTTAAAATGCTTGATATGGctttttatatgtgttactcta c" /listShort="S861, hbs, S860, folEA, mtrB, S859, hepS, menH, hepT, ndk, S858, cheR" /listLong="aroF, aroB, aroH, S857, trpE, trpD, trpC, trpF, trpB, trpA, hisC, tyrA, aroE, S856, S855, ypiA, ypiB, ypiF" promotor_-35 complement(2251663..2251668) /Source="Nicolas_upshift_promotors" /id="U1780" /multdbtbs="SigA" /comp="M17" /sig="SigA" /pcomp="0.591408591408591" /psig="0.998001998001998" /xcortree=2643 /SigmaFactorBS="aaaaaaggaatattcgttcggtaaatcaccttaaatcCTTGA CgagcaagggattgacgCTTTAAAATGCTTGATATGGctttttatatgtgttactcta c" /listShort="S861, hbs, S860, folEA, mtrB, S859, hepS, menH, hepT, ndk, S858, cheR" /listLong="aroF, aroB, aroH, S857, trpE, trpD, trpC, trpF, trpB, trpA, hisC, tyrA, aroE, S856, S855, ypiA, ypiB, ypiF" /label="promotor_-35" CDS complement(2251793..2253271) /gene="spoIVA" /locus_tag="BSU_22800" /old_locus_tag="BSU22800" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:11160095, 17114257, 17427285, 24810258, 26387458, 28408070" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11160095, 17114257, 17427285, 24810258, 26387458, 28408070; Product type cp : cell process" /codon_start=1 /transl_table=11 /product="morphogenetic stage IV sporulation protein" /protein_id="NP_390161.1" /db_xref="EnsemblGenomes-Gn:BSU22800" /db_xref="EnsemblGenomes-Tr:CAB14196" /db_xref="GOA:P35149" /db_xref="InterPro:IPR014201" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG10275" /db_xref="UniProtKB/Swiss-Prot:P35149" /translation="MEKVDIFKDIAERTGGDIYLGVVGAVRTGKSTFIKKFMELVVLP NISNEADRARAQDELPQSAAGKTIMTTEPKFVPNQAMSVHVSDGLDVNIRLVDCVGYT VPGAKGYEDENGPRMINTPWYEEPIPFHEAAEIGTRKVIQEHSTIGVVITTDGTIGDI ARSDYIEAEERVIEELKEVGKPFIMVINSVRPYHPETEAMRQDLSEKYDIPVLAMSVE SMRESDVLSVLREALYEFPVLEVNVNLPSWVMVLKENHWLRESYQESVKETVKDIKRL RDVDRVVGQFSEFEFIESAGLAGIELGQGVAEIDLYAPDHLYDQILKEVVGVEIRGRD HLLELMQDFAHAKTEYDQVSDALKMVKQTGYGIAAPALADMSLDEPEIIRQGSRFGVR LKAVAPSIHMIKVDVESEFAPIIGTEKQSEELVRYLMQDFEDDPLSIWNSDIFGRSLS SIVREGIQAKLSLMPENARYKLKETLERIINEGSGGLIAIIL*" gene complement(2251793..2253271) /gene="spoIVA" /locus_tag="BSU_22800" /old_locus_tag="BSU22800" downshifts complement(2251806) /Source="Nicolas_upshifts" /id="D1188" /incds=0 /nref=59 /ntot=76 /MaxReadThrough="3.43222" /MaxDrop="7.13908" /score="13.6316529" /energy="-9.2" /TU="U1781" /idTUdmin="U1782" /TUdmin=0 /isTUend="TRUE" S_feature complement(2253272..2253433) /Source="Nicolas_S_feature" /locus_tag="new_2387674_2387835_c" /HighExp="S3, S4, S5, S6, LoTm, S7, B36, BT, T5.0H, S8" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigEF, SigA" /TUshortPSig="1, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S862" promotor_-10 complement(2253420..2253438) /Source="Nicolas_upshift_promotors" /id="U1781" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1096 /SigmaFactorBS="gtaaatgacaaacaggaacctgtttttttagaaaatgatatg aaaaaGGAATGaacctttctcccttGCATACAAATAGGGAGAAAggtttttttatatt a" /listShort="S862, spoIVA" /listLong="S861, hbs, S860, folEA, mtrB, S859, hepS, menH, hepT, ndk, S858" /label="promotor_-10" upshifts complement(2253445) /Source="Nicolas_upshifts" /id="U1781" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1096 /SigmaFactorBS="gtaaatgacaaacaggaacctgtttttttagaaaatgatatg aaaaaGGAATGaacctttctcccttGCATACAAATAGGGAGAAAggtttttttatatt a" /listShort="S862, spoIVA" /listLong="S861, hbs, S860, folEA, mtrB, S859, hepS, menH, hepT, ndk, S858" CDS complement(2253452..2254186) /gene="yphF" /locus_tag="BSU_22810" /old_locus_tag="BSU22810" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type lp: lipoprotein" /codon_start=1 /transl_table=11 /product="putative lipoprotein of unknown function" /protein_id="NP_390162.1" /db_xref="EnsemblGenomes-Gn:BSU22810" /db_xref="EnsemblGenomes-Tr:CAB14197" /db_xref="SubtiList:BG10274" /db_xref="UniProtKB/Swiss-Prot:P39911" /translation="MGKLKCAIIFAAVVFLSGCLYPNERKSSVHAIPYQDQLKQVQSA VDEFQKANGGLLPIQTKDMSTPLYQKYPIDFNRLAPRYIAEPPSTAFESGGDYQYVLV DVENDPTVKLIDLKMAEKIRDVKLRIQMYRQEHQYPPYKDVLSRDLFTLDEKKLGDGS SLTVTSPISGNSLPLMIDGDGEIYADYRTELASCLKKSKKTFKPGTEIQDMIWHETPF VPAFSVKYTVNDKQEPVFLENDMKKE*" gene complement(2253452..2254186) /gene="yphF" /locus_tag="BSU_22810" /old_locus_tag="BSU22810" promotor_-35 complement(2253453..2253458) /Source="Nicolas_upshift_promotors" /id="U1781" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1096 /SigmaFactorBS="gtaaatgacaaacaggaacctgtttttttagaaaatgatatg aaaaaGGAATGaacctttctcccttGCATACAAATAGGGAGAAAggtttttttatatt a" /listShort="S862, spoIVA" /listLong="S861, hbs, S860, folEA, mtrB, S859, hepS, menH, hepT, ndk, S858" /label="promotor_-35" downshifts complement(2253478) /Source="Nicolas_upshifts" /id="D1189" /incds=0 /nref=6 /ntot=78 /MaxReadThrough="6.50932" /MaxDrop="4.759" /score="15.8109079" /energy="-12.7" /TU="U1782" /idTUdmin="U1783" /TUdmin=1100 /isTUend="FALSE" CDS complement(2254208..2254411) /gene="yphE" /locus_tag="BSU_22820" /old_locus_tag="BSU22820" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_390163.1" /db_xref="EnsemblGenomes-Gn:BSU22820" /db_xref="EnsemblGenomes-Tr:CAB14198" /db_xref="GOA:P50744" /db_xref="InterPro:IPR020076" /db_xref="SubtiList:BG11444" /db_xref="UniProtKB/Swiss-Prot:P50744" /translation="MNLALMKMWFALGSMGLMFLAVASIYLSRFKCQNRFLKIAISSF AYMCMLISGIIVFVVVFSGPVNE*" gene complement(2254208..2254411) /gene="yphE" /locus_tag="BSU_22820" /old_locus_tag="BSU22820" promotor_-10 complement(2254447..2254466) /Source="Nicolas_upshift_promotors" /id="U1782" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.491508491508492" /psig=1 /xcortree=3051 /SigmaFactorBS="tttgcttcagtttttttgttctatcaatggatggaaaatctG GTTGATCttttccggcgctgTATATTAAAATATAATATAAcgcttatatcttacatat c" /listShort="yphE, yphF, S862, spoIVA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2254468) /Source="Nicolas_upshifts" /id="U1782" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.491508491508492" /psig=1 /xcortree=3051 /SigmaFactorBS="tttgcttcagtttttttgttctatcaatggatggaaaatctG GTTGATCttttccggcgctgTATATTAAAATATAATATAAcgcttatatcttacatat c" /listShort="yphE, yphF, S862, spoIVA" /GFF_Attribute="listLong" promotor_-35 complement(2254480..2254487) /Source="Nicolas_upshift_promotors" /id="U1782" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.491508491508492" /psig=1 /xcortree=3051 /SigmaFactorBS="tttgcttcagtttttttgttctatcaatggatggaaaatctG GTTGATCttttccggcgctgTATATTAAAATATAATATAAcgcttatatcttacatat c" /listShort="yphE, yphF, S862, spoIVA" /GFF_Attribute="listLong" /label="promotor_-35" S_feature complement(2254533..2254732) /Source="Nicolas_S_feature" /locus_tag="new_2388935_2389134_c" /HighExp="S7, S8, S6, C30, BT, G135, G180, Oxctl, Cold, LBGstat" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigK, SigA, Sig-" /TUshortPSig="1, 1, 0.481" /TUlongSig="NA" /TUlongPSig="NA" /label="S863" downshifts complement(2254576) /Source="Nicolas_upshifts" /id="D1190" /incds=0 /nref=264 /ntot=295 /MaxReadThrough="2.22999" /MaxDrop="8.05743" /score="26.216597" /energy="-14.1" /TU="NA" /idTUdmin="U1783" /TUdmin=2 /isTUend="TRUE" promotor_-10 complement(2254707..2254726) /Source="Nicolas_upshift_promotors" /id="U1783" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1314 /SigmaFactorBS="agatggaggatttggtaaatacgtttgaaaatcaagtgaagt aAAAGTGTCAAtcaaatggtgaatCGCATATCTTAATTGAACGAaagcccgaaaaaca g" /listShort="S863" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2254732) /Source="Nicolas_upshifts" /id="U1783" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1314 /SigmaFactorBS="agatggaggatttggtaaatacgtttgaaaatcaagtgaagt aAAAGTGTCAAtcaaatggtgaatCGCATATCTTAATTGAACGAaagcccgaaaaaca g" /listShort="S863" /GFF_Attribute="listLong" promotor_-35 complement(2254740..2254749) /Source="Nicolas_upshift_promotors" /id="U1783" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1314 /SigmaFactorBS="agatggaggatttggtaaatacgtttgaaaatcaagtgaagt aAAAGTGTCAAtcaaatggtgaatCGCATATCTTAATTGAACGAaagcccgaaaaaca g" /listShort="S863" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2254749..2255786) /gene="gpsA" /locus_tag="BSU_22830" /old_locus_tag="BSU22830" /EC_number="1.1.1.94" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:7592341, 12682299, 15557260" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7592341, 12682299, 15557260; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="NADPH-dependent glycerol-3-phosphate dehydrogenase" /protein_id="NP_390164.1" /db_xref="EnsemblGenomes-Gn:BSU22830" /db_xref="EnsemblGenomes-Tr:CAB14199" /db_xref="GOA:P46919" /db_xref="InterPro:IPR006109" /db_xref="InterPro:IPR006168" /db_xref="InterPro:IPR008927" /db_xref="InterPro:IPR011128" /db_xref="InterPro:IPR013328" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG11366" /db_xref="UniProtKB/Swiss-Prot:P46919" /translation="MKKVTMLGAGSWGTALALVLTDNGNEVCVWAHRADLIHQINELH ENKDYLPNVKLSTSIKGTTDMKEAVSDADVIIVAVPTKAIREVLRQAVPFITKKAVFV HVSKGIEPDSLLRISEIMEIELPSDVRKDIVVLSGPSHAEEVGLRHPTTVTASSKSMR AAEEVQDLFINHNFRVYTNPDIIGVEIGGALKNIIALAAGITDGLGYGDNAKAALITR GLAEIARLGTKMGGNPLTFSGLTGVGDLIVTCTSVHSRNWRAGNLLGKGYKLEDVLEE MGMVVEGVRTTKAAYQLSKKYDVKMPITEALHQVLFNGQKVETAVESLMARGKTHEME DLVNTFENQVK*" gene complement(2254749..2255786) /gene="gpsA" /locus_tag="BSU_22830" /old_locus_tag="BSU22830" CDS complement(2255804..2257114) /gene="der" /locus_tag="BSU_22840" /old_locus_tag="BSU22840" /EC_number="3.6.5.-" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:12682299, 16682769, 16894162, 16997968, 19246542, 23056455, 24822275, 27484475" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12682299, 16682769, 16894162, 16997968, 19246542, 23056455, 24822275, 27484475; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="GTPase essential for ribosome 50S subunit assembly (maturation of the 50S subunit central protoberance)" /protein_id="NP_390165.1" /db_xref="EnsemblGenomes-Gn:BSU22840" /db_xref="EnsemblGenomes-Tr:CAB14200" /db_xref="GOA:P50743" /db_xref="InterPro:IPR005225" /db_xref="InterPro:IPR006073" /db_xref="InterPro:IPR015946" /db_xref="InterPro:IPR016484" /db_xref="InterPro:IPR027368" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR031166" /db_xref="InterPro:IPR032859" /db_xref="PDB:2HJG" /db_xref="PDB:4DCS" /db_xref="PDB:4DCT" /db_xref="PDB:4DCU" /db_xref="PDB:4DCV" /db_xref="PDB:4KYU" /db_xref="PDB:5X4B" /db_xref="SubtiList:BG11443" /db_xref="UniProtKB/Swiss-Prot:P50743" /translation="MGKPVVAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYS SAEWLNYDFNLIDTGGIDIGDEPFLAQIRQQAEIAMDEADVIIFMVNGREGVTAADEE VAKILYRTKKPVVLAVNKLDNTEMRANIYDFYSLGFGEPYPISGTHGLGLGDLLDAVA EHFKNIPETKYNEEVIQFCLIGRPNVGKSSLVNAMLGEERVIVSNVAGTTRDAVDTSF TYNQQEFVIVDTAGMRKKGKVYETTEKYSVLRALKAIDRSEVVAVVLDGEEGIIEQDK RIAGYAHEAGKAVVIVVNKWDAVDKDESTMKEFEENIRDHFQFLDYAPILFMSALTKK RIHTLMPAIIKASENHSLRVQTNVLNDVIMDAVAMNPTPTHNGSRLKIYYATQVSVKP PSFVVFVNDPELMHFSYERFLENRIRDAFGFEGTPIKIFARARK*" gene complement(2255804..2257114) /gene="der" /locus_tag="BSU_22840" /old_locus_tag="BSU22840" S_feature complement(2257115..2257239) /Source="Nicolas_S_feature" /locus_tag="new_2391517_2391641_c" /HighExp="Cold, G180, G150, Oxctl, G135, C30, LBGexp, Paraq, dia0, H2O2" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, Sig-" /TUshortPSig="1, 0.481" /TUlongSig="NA" /TUlongPSig="NA" /label="S864" promotor_-10 complement(2257225..2257244) /Source="Nicolas_upshift_promotors" /id="U1784" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.706293706293706" /psig=1 /xcortree=2499 /SigmaFactorBS="atgacgtgtatttgatcgtgaaacatttttaagaataGTTGt gatcccagtaaaaACTGATATAATAAATGAGTTaagcccttcctctgaagggtttctt t" /listShort="S864, engA, gpsA, S863" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2257239) /Source="Nicolas_upshifts" /id="U1784" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.706293706293706" /psig=1 /xcortree=2499 /SigmaFactorBS="atgacgtgtatttgatcgtgaaacatttttaagaataGTTGt gatcccagtaaaaACTGATATAATAAATGAGTTaagcccttcctctgaagggtttctt t" /listShort="S864, engA, gpsA, S863" /GFF_Attribute="listLong" promotor_-35 complement(2257259..2257262) /Source="Nicolas_upshift_promotors" /id="U1784" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.706293706293706" /psig=1 /xcortree=2499 /SigmaFactorBS="atgacgtgtatttgatcgtgaaacatttttaagaataGTTGt gatcccagtaaaaACTGATATAATAAATGAGTTaagcccttcctctgaagggtttctt t" /listShort="S864, engA, gpsA, S863" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2257268..2257462) /gene="ypzH" /locus_tag="BSU_22849" /old_locus_tag="BSU22849" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="YP_003097755.1" /db_xref="EnsemblGenomes-Gn:BSU22849" /db_xref="EnsemblGenomes-Tr:CAX52654" /db_xref="UniProtKB/Swiss-Prot:C0H445" /translation="MSESLTKVILSVITTNRNRVAGGAPVFFCNDQKEMELFAKNLEA ILDGIAHRIGDDVYLIVKHF*" gene complement(2257268..2257462) /gene="ypzH" /locus_tag="BSU_22849" /old_locus_tag="BSU22849" CDS complement(2257459..2258352) /gene="yphB" /locus_tag="BSU_22850" /old_locus_tag="BSU22850" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved membrane protein of unknown function" /protein_id="NP_390166.1" /db_xref="EnsemblGenomes-Gn:BSU22850" /db_xref="EnsemblGenomes-Tr:CAB14201" /db_xref="GOA:P50742" /db_xref="InterPro:IPR025918" /db_xref="SubtiList:BG11442" /db_xref="UniProtKB/Swiss-Prot:P50742" /translation="MSDYIYPIIAGVIAGIATRLYMLKTDYRQYPTYVHGKVIHIALG LIAAGLGAIIMPALLQEEFTAITFLTLAATQFRDVRNMERNTLTQMDSYELVSRGSTY IEGIAIAFESRNYIVIFTALLTTSAYVFLSIWAAVIAAVVCFLLAMKFMSGSVLKDIV DIEYIKPRFDGPGLFVDNIYMMNIGLPEKQELILKHGMGFILTPKNFNSAATIANLGQ RQAILFDVSNVLGVYRDSGEPSLTPIAKRDLNDGRVAVFVLPQIHHPETAVQIISNVP TLENAIRMPTEFIKNQDKVIG*" gene complement(2257459..2258352) /gene="yphB" /locus_tag="BSU_22850" /old_locus_tag="BSU22850" CDS complement(2258349..2258948) /gene="yphA" /locus_tag="BSU_22860" /old_locus_tag="BSU22860" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 15849754, 16850406; Product type m:membrane component" /codon_start=1 /transl_table=11 /product="conserved membrane protein of unknown function" /protein_id="NP_390167.1" /db_xref="EnsemblGenomes-Gn:BSU22860" /db_xref="EnsemblGenomes-Tr:CAB14202" /db_xref="GOA:P50741" /db_xref="InterPro:IPR014617" /db_xref="SubtiList:BG11441" /db_xref="UniProtKB/Swiss-Prot:P50741" /translation="MEQFYYYWSMWFLWVLTTFIFEKTKRRIAVSVFILTNIILSIHD IALYFSLNAAYLMFFVCGCVYAGYLGMYRFRYIMVYLTLVAAYAFVYLFALYDPVWFI IKPEWAAVILIVLLTASVERNFEKQLVLFVLGMCQGELVYSFVIQKLAGAMAVGGFQW LNACSAGMILLFGISKYEHLASQIGQKSKRSNKGATKMS*" gene complement(2258349..2258948) /gene="yphA" /locus_tag="BSU_22860" /old_locus_tag="BSU22860" promotor_-35 2258821..2258827 /Source="Nicolas_upshift_promotors" /id="U1785" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.6003996003996" /psig="0.6003996003996" /xcortree=787 /SigmaFactorBS="catcaaatatgcagcattcagggaaaaatataaagcgatgtc aTGTATGCttagaataatattAGTTAAAATAAAgacagagacggcaattcgtcttttc g" /listShort="S865, ypzI" /GFF_Attribute="listLong" /label="promotor_-35" S_feature 2258836..2259019 /Source="Nicolas_S_feature" /locus_tag="new_2393238_2393421" /HighExp="S5, S8, S6, S7, BT, S4, ferm, nit, Pyr, G/S" /AntisenseName="yphA" /AntisenseCor="0.73324773408178501" /AntisenseRegPval="-45.9" /CDS_PredictionProba="NA" /TUshortSig="SigGF" /TUshortPSig="0.6" /TUlongSig="NA" /TUlongPSig="NA" /label="S865" upshifts 2258838 /Source="Nicolas_upshifts" /id="U1785" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.6003996003996" /psig="0.6003996003996" /xcortree=787 /SigmaFactorBS="catcaaatatgcagcattcagggaaaaatataaagcgatgtc aTGTATGCttagaataatattAGTTAAAATAAAgacagagacggcaattcgtcttttc g" /listShort="S865, ypzI" /GFF_Attribute="listLong" promotor_-10 2258841..2258852 /Source="Nicolas_upshift_promotors" /id="U1785" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.6003996003996" /psig="0.6003996003996" /xcortree=787 /SigmaFactorBS="catcaaatatgcagcattcagggaaaaatataaagcgatgtc aTGTATGCttagaataatattAGTTAAAATAAAgacagagacggcaattcgtcttttc g" /listShort="S865, ypzI" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-10 complement(2258959..2258977) /Source="Nicolas_upshift_promotors" /id="U1786" /multdbtbs="-" /comp="M3" /sig="Sig-" /pcomp="0.48051948051948" /psig="0.48051948051948" /xcortree=969 /SigmaFactorBS="tgtcttttcccatgatcatactccttaatgtgagatcgatTG TTTAaaaaatgtgcttgaaCTCCATACTGGGAATATGGaggaagtaaaatggaacaat t" /listShort="yphA, seaA, ypzH, S864, engA, gpsA, S863" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2258978) /Source="Nicolas_upshifts" /id="U1786" /multdbtbs="-" /comp="M3" /sig="Sig-" /pcomp="0.48051948051948" /psig="0.48051948051948" /xcortree=969 /SigmaFactorBS="tgtcttttcccatgatcatactccttaatgtgagatcgatTG TTTAaaaaatgtgcttgaaCTCCATACTGGGAATATGGaggaagtaaaatggaacaat t" /listShort="yphA, seaA, ypzH, S864, engA, gpsA, S863" /GFF_Attribute="listLong" promotor_-35 complement(2258993..2258998) /Source="Nicolas_upshift_promotors" /id="U1786" /multdbtbs="-" /comp="M3" /sig="Sig-" /pcomp="0.48051948051948" /psig="0.48051948051948" /xcortree=969 /SigmaFactorBS="tgtcttttcccatgatcatactccttaatgtgagatcgatTG TTTAaaaaatgtgcttgaaCTCCATACTGGGAATATGGaggaagtaaaatggaacaat t" /listShort="yphA, seaA, ypzH, S864, engA, gpsA, S863" /GFF_Attribute="listLong" /label="promotor_-35" CDS 2259026..2259157 /gene="ypzI" /locus_tag="BSU_22869" /old_locus_tag="BSU22869" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences" /codon_start=1 /transl_table=11 /product="putative sporulation-related protein" /protein_id="YP_003097756.2" /db_xref="EnsemblGenomes-Gn:BSU22869" /db_xref="EnsemblGenomes-Tr:CAX52655" /db_xref="InterPro:IPR025414" /db_xref="UniProtKB/Swiss-Prot:C0H446" /translation="MGKDRQEKKLKASGRVESDRDQSIHYDGATSLEQNGRFKKRKS* " gene 2259026..2259157 /gene="ypzI" /locus_tag="BSU_22869" /old_locus_tag="BSU22869" downshifts 2259145 /Source="Nicolas_upshifts" /id="D1191" /incds=0 /nref=37 /ntot=122 /MaxReadThrough="0.20384" /MaxDrop="6.94664" /score="3.33160455" /energy="-13.2" /TU="NA" /idTUdmin="U1785" /TUdmin=1 /isTUend="TRUE" CDS complement(2259200..2260249) /gene="fni" /locus_tag="BSU_22870" /old_locus_tag="BSU22870" /EC_number="5.3.3.2" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:12798687, 14745175, 15206931" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12798687, 14745175, 15206931; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="isopentenyl diphosphate isomerase (typeII)" /protein_id="NP_390168.3" /db_xref="EnsemblGenomes-Gn:BSU22870" /db_xref="EnsemblGenomes-Tr:CAB14203" /db_xref="GOA:P50740" /db_xref="InterPro:IPR000262" /db_xref="InterPro:IPR011179" /db_xref="InterPro:IPR013785" /db_xref="PDB:1P0K" /db_xref="PDB:1P0N" /db_xref="SubtiList:BG11440" /db_xref="UniProtKB/Swiss-Prot:P50740" /translation="MTRAERKRQHINHALSIGQKRETGLDDITFVHVSLPDLALEQVD ISTKIGELSSSSPIFINAMTGGGGKLTYEINKSLARAASQAGIPLAVGSQMSALKDPS ERLSYEIVRKENPNGLIFANLGSEATAAQAKEAVEMIGANALQIHLNVIQEIVMPEGD RSFSGALKRIEQICSRVSVPVIVKEVGFGMSKASAGKLYEAGAAAVDIGGYGGTNFSK IENLRRQRQISFFNSWGISTAASLAEIRSEFPASTMIASGGLQDALDVAKAIALGASC TGMAGHFLKALTDSGEEGLLEEIQLILEELKLIMTVLGARTIADLQKAPLVIKGETHH WLTERGVNTSSYSVR*" gene complement(2259200..2260249) /gene="fni" /locus_tag="BSU_22870" /old_locus_tag="BSU22870" downshifts complement(2259220) /Source="Nicolas_upshifts" /id="D1192" /incds=0 /nref=209 /ntot=250 /MaxReadThrough="1.39069" /MaxDrop="4.82362" /score="15.2467448" /energy="-13.2" /TU="NA" /idTUdmin="U1788" /TUdmin=0 /isTUend="TRUE" downshifts complement(2260124) /Source="Nicolas_upshifts" /id="D1193" /incds=1 /nref=45 /ntot=237 /MaxReadThrough="6.15611" /MaxDrop="4.91722" /score="13.2731686" /energy="-15.7" /TU="U1788,U1789,U1790" /idTUdmin="U1788" /TUdmin="-904" /isTUend="FALSE" CDS complement(2260262..2261410) /gene="rpfA" /locus_tag="BSU_22880" /old_locus_tag="BSU22880" /function="16.11: Scavenge (Catabolism)" /function="16.6: Maintain" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 9179491, 9862121, 14586115; Product type f: factor" /codon_start=1 /transl_table=11 /product="RNA degradation presenting factor (ribosomal protein S1 homolog)" /protein_id="NP_390169.1" /db_xref="EnsemblGenomes-Gn:BSU22880" /db_xref="EnsemblGenomes-Tr:CAB14204" /db_xref="GOA:P38494" /db_xref="InterPro:IPR003029" /db_xref="InterPro:IPR012340" /db_xref="InterPro:IPR022967" /db_xref="SubtiList:BG11005" /db_xref="UniProtKB/Swiss-Prot:P38494" /translation="MTEEMNQIDVQVPEVGDVVKGIVTKVEDKHVDVEIINVKQSGII PISELSSLHVEKASDVVKVDDELDLKVTKVEDDALILSKRAVDADRAWEDLEKKFETK EVFEAEVKDVVKGGLVVDIGVRGFIPASLVEAHFVEDFTDYKGKTLSLLVVELDRDKN RVILSHRAVVESEQANKKQELLQSLEVGSVLDGKVQRLTDFGAFVDIGGIDGLVHISQ LSHSHVEKPSDVVEEGQEVKVKVLSVDRDNERISLSIKDTLPGPWNQIGEKVKPGDVL EGTVQRLVSFGAFVEILPGVEGLVHISQISNKHIGTPHEVLEEGQTVKVKVLDVNENE ERISLSMRELEETPKADQEDYRQYQAKEETSTGFQLGDLIGDKLNKLK*" gene complement(2260262..2261410) /gene="rpfA" /locus_tag="BSU_22880" /old_locus_tag="BSU22880" misc_feature 2260591..2260594 /Source="Nicolas_upshift_promotors" /id="U1787" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.677322677322677" /psig="0.023976023976024" /xcortree=89 /SigmaFactorBS="ttacaagacgctgtacagttccttcaagcacatCGCCaggct tcactttttcgccgatttggttccaaggtccaggcagtgtatctttgatcgataaaga a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 2260618 /Source="Nicolas_upshifts" /id="U1787" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.677322677322677" /psig="0.023976023976024" /xcortree=89 /SigmaFactorBS="ttacaagacgctgtacagttccttcaagcacatCGCCaggct tcactttttcgccgatttggttccaaggtccaggcagtgtatctttgatcgataaaga a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" downshifts 2260684 /Source="Nicolas_upshifts" /id="D1194" /incds=1 /nref=1 /ntot=124 /MaxReadThrough="1.88188" /MaxDrop="2.8624" /score="-3.97389972" /energy="-11.8" /TU="NA" /idTUdmin="U1787" /TUdmin=0 /isTUend="TRUE" downshifts 2261388 /Source="Nicolas_upshifts" /id="D1195" /incds=0 /nref=3 /ntot=200 /MaxReadThrough="1.33117" /MaxDrop="3.08345" /score="-3.97389972" /energy="-11.8" /TU="NA" /idTUdmin="U1787" /TUdmin=704 /isTUend="FALSE" S_feature complement(2261411..2261550) /Source="Nicolas_S_feature" /locus_tag="new_2395813_2395952_c" /HighExp="C90, Salt, Etha, Lbtran, HiOs, M40t90, S1, LBGtran, LoTm, M0t90" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigEF, SigA" /TUshortPSig="0.999, 0.703, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S866" promotor_-10 complement(2261549..2261568) /Source="Nicolas_upshift_promotors" /id="U1788" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.802197802197802" /psig="0.999000999001" /xcortree=2236 /SigmaFactorBS="aacgaagatagaatgttattGCTTGACAaacctgtcctttta TTAGAAGTTAATACTAATAAaactttttattgatcattcaaaaaacttttttggatga t" /listShort="S866, ypfD, fni" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2261550) /Source="Nicolas_upshifts" /id="U1788" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.802197802197802" /psig="0.999000999001" /xcortree=2236 /SigmaFactorBS="aacgaagatagaatgttattGCTTGACAaacctgtcctttta TTAGAAGTTAATACTAATAAaactttttattgatcattcaaaaaacttttttggatga t" /listShort="S866, ypfD, fni" /GFF_Attribute="listLong" S_feature complement(2261552..2261642) /Source="Nicolas_S_feature" /locus_tag="new_2395954_2396044_c" /HighExp="G135, G180, LBGexp, C30, Cold, Oxctl, dia0, G150, Paraq, H2O2" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.40511799999999998" /TUshortSig="SigEF, SigA" /TUshortPSig="0.703, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S867" promotor_-35 complement(2261583..2261590) /Source="Nicolas_upshift_promotors" /id="U1788" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.802197802197802" /psig="0.999000999001" /xcortree=2236 /SigmaFactorBS="aacgaagatagaatgttattGCTTGACAaacctgtcctttta TTAGAAGTTAATACTAATAAaactttttattgatcattcaaaaaacttttttggatga t" /listShort="S866, ypfD, fni" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2261643..2262317) /gene="cmk" /locus_tag="BSU_22890" /old_locus_tag="BSU22890" /EC_number="2.7.4.25" /function="16.2: Construct biomass (Anabolism)" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:8576266, 9179491, 9862121, 11827479, 12682299, 16880539" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8576266, 9179491, 9862121, 11827479, 12682299, 16880539; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="cytidylate kinase" /protein_id="NP_390170.1" /db_xref="EnsemblGenomes-Gn:BSU22890" /db_xref="EnsemblGenomes-Tr:CAB14205" /db_xref="GOA:P38493" /db_xref="InterPro:IPR003136" /db_xref="InterPro:IPR011994" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG11004" /db_xref="UniProtKB/Swiss-Prot:P38493" /translation="MEKKLSIAIDGPAAAGKSTVAKIVAEKKSYIYIDTGAMYRAITY AALQENVDLTDEEKLAELLKRTDIELITTKDGQKVFVNGTDVTEAIRTDEISNQVSIA AKHRSVREEMVKRQQQLGEKGGVVMDGRDIGTHVLPNAEVKIFLLASVEERAKRRYEE NVKKGFDVNYETLIEEIARRDKLDSEREVSPLRKAEDALEIDTTSLSIQEVADKILEA VEQKSR*" gene complement(2261643..2262317) /gene="cmk" /locus_tag="BSU_22890" /old_locus_tag="BSU22890" S_feature complement(2262318..2262395) /Source="Nicolas_S_feature" /locus_tag="new_2396720_2396797_c" /HighExp="S4, S5, S7, S8, S6, dia15, S3, Diami, dia5, LBGtran" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigEF, SigA" /TUshortPSig="0.703, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S868" CDS complement(2262396..2262572) /gene="ypfB" /locus_tag="BSU_22900" /old_locus_tag="BSU22900" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_390171.1" /db_xref="EnsemblGenomes-Gn:BSU22900" /db_xref="EnsemblGenomes-Tr:CAB14206" /db_xref="InterPro:IPR035281" /db_xref="SubtiList:BG11003" /db_xref="UniProtKB/Swiss-Prot:P38492" /translation="MKTFERLLIKLLFIQAIILLGVQFLFHYQHIEPYVSKVIQYEGV DKMEENNRIETFKH*" gene complement(2262396..2262572) /gene="ypfB" /locus_tag="BSU_22900" /old_locus_tag="BSU22900" promotor_-10 complement(2262584..2262602) /Source="Nicolas_upshift_promotors" /id="U1789" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.703296703296703" /psig="0.703296703296703" /xcortree=1196 /SigmaFactorBS="atcaggcgccagttaaataagagaagaaaggcccgaatGGAA TAAacatcggcaaacacTTCCATACTATTTGTAATGgaggtgctccaatgaaaacatt t" /listShort="ypfB, S868, cmk, S867, S866, ypfD, fni" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2262601) /Source="Nicolas_upshifts" /id="U1789" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.703296703296703" /psig="0.703296703296703" /xcortree=1196 /SigmaFactorBS="atcaggcgccagttaaataagagaagaaaggcccgaatGGAA TAAacatcggcaaacacTTCCATACTATTTGTAATGgaggtgctccaatgaaaacatt t" /listShort="ypfB, S868, cmk, S867, S866, ypfD, fni" /GFF_Attribute="listLong" promotor_-35 complement(2262617..2262623) /Source="Nicolas_upshift_promotors" /id="U1789" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.703296703296703" /psig="0.703296703296703" /xcortree=1196 /SigmaFactorBS="atcaggcgccagttaaataagagaagaaaggcccgaatGGAA TAAacatcggcaaacacTTCCATACTATTTGTAATGgaggtgctccaatgaaaacatt t" /listShort="ypfB, S868, cmk, S867, S866, ypfD, fni" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2262617..2263270) /gene="dgrA" /locus_tag="BSU_22910" /old_locus_tag="BSU22910" /function="16.12: Sense" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:16249258, 23893111, 28536559" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16249258, 23893111, 28536559; Product type rc: receptor" /codon_start=1 /transl_table=11 /product="cyclic di-GMP receptor" /protein_id="NP_390172.1" /db_xref="EnsemblGenomes-Gn:BSU22910" /db_xref="EnsemblGenomes-Tr:CAB14207" /db_xref="GOA:P38491" /db_xref="InterPro:IPR009875" /db_xref="InterPro:IPR009926" /db_xref="InterPro:IPR012349" /db_xref="SubtiList:BG11002" /db_xref="UniProtKB/Swiss-Prot:P38491" /translation="MIEIGENVLLEYIEENELKKAKSKAVSIENNELLIAYPVDVVTG RTVILHNDMEVTVEFVGKDEVPYRFISRIKGKVKDKLQMICLEMPPREKMKRIQRRQY VRTDAVLDVQIQPGNEEEIRTLSYNISAGGIAVVLADGLSFQSGESLRLIIRLPEEEH TRQIETEAVVRRIFNDPKSEKRKMTLEYSEIAAGDQQALLQYCIRRQLNKRRKARME* " gene complement(2262617..2263270) /gene="dgrA" /locus_tag="BSU_22910" /old_locus_tag="BSU22910" promotor_-10 complement(2263300..2263319) /Source="Nicolas_upshift_promotors" /id="U1790" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.971028971028971" /psig=1 /xcortree=2544 /SigmaFactorBS="aagacctataaaaacaggaggaaaggactaaatgTCTTTtcc tttttttcattaCGTGCTTTAATAAAAACGTGagtatattgaatgcgaaagagtgaag t" /listShort="ypfA, ypfB, S868, cmk, S867, S866, ypfD, fni" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2263313) /Source="Nicolas_upshifts" /id="U1790" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.971028971028971" /psig=1 /xcortree=2544 /SigmaFactorBS="aagacctataaaaacaggaggaaaggactaaatgTCTTTtcc tttttttcattaCGTGCTTTAATAAAAACGTGagtatattgaatgcgaaagagtgaag t" /listShort="ypfA, ypfB, S868, cmk, S867, S866, ypfD, fni" /GFF_Attribute="listLong" promotor_-35 complement(2263335..2263339) /Source="Nicolas_upshift_promotors" /id="U1790" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.971028971028971" /psig=1 /xcortree=2544 /SigmaFactorBS="aagacctataaaaacaggaggaaaggactaaatgTCTTTtcc tttttttcattaCGTGCTTTAATAAAAACGTGagtatattgaatgcgaaagagtgaag t" /listShort="ypfA, ypfB, S868, cmk, S867, S866, ypfD, fni" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2263363..2264715) /gene="sleC" /locus_tag="BSU_22920" /old_locus_tag="BSU22920" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:10658652, 12177332, 22720735, 23543708, 24752279, 25022853, 25384476, 26187959" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10658652, 12177332, 22720735, 23543708, 24752279, 25022853, 25384476, 26187959; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="spore germination membrane component" /protein_id="NP_390173.1" /db_xref="EnsemblGenomes-Gn:BSU22920" /db_xref="EnsemblGenomes-Tr:CAB14208" /db_xref="GOA:P38490" /db_xref="InterPro:IPR014239" /db_xref="InterPro:IPR025711" /db_xref="SubtiList:BG11001" /db_xref="UniProtKB/Swiss-Prot:P38490" /translation="MIRGILIAVLGIAIVGTGYWGYKEHQEKDAVLLHAENNYQRAFH ELTYQVDQLHDKIGTTLAMNSQKSLSPALIDVWRITSEAHNSVSQLPLTLMPFNKTEE LLSKIGDFSYKTSVRDLDQKPLDKNEYTSLNKLYQQSEDIQNELRHVQHLVMSKNLRW MDVEMALASDEKQSDNTIINSFKTVEKNVGAFSTGTDLGPSFTSTKKEEKGFSHLKGK QISEQEAKQIAERFAPDDNYSIKVVKSGKKTNRDVYSISMKDPDHKAVIYMDITKKGG HPVYLIQNREVKDQKISLNDGSNRALAFLKKNGFETDDLEIDESAQYDKIGVFSYVPV ENKVRMYPEAIRMKVALDDGEVVGFSARDFLTSHRKRTIPKPAITEAEAKSKLNKNVQ VRETRLALITNELGQEVLCYEMLGTIENDTFRMYINAKDGSEEKVEKLKNAEPIYKDL *" gene complement(2263363..2264715) /gene="sleC" /locus_tag="BSU_22920" /old_locus_tag="BSU22920" downshifts complement(2263378) /Source="Nicolas_upshifts" /id="D1196" /incds=0 /nref=21 /ntot=44 /MaxReadThrough="0.647060000000002" /MaxDrop="5.74199" /score="16.6521528" /energy="-10.1" /TU="NA" /idTUdmin="U1791" /TUdmin=0 /isTUend="TRUE" CDS complement(2264750..2265667) /gene="sleB" /locus_tag="BSU_22930" /old_locus_tag="BSU22930" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:10658652, 12177332, 16905870, 16907803, 25963559, 26187959, 28333204" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10658652, 12177332, 16905870, 16907803, 25963559, 26187959, 28333204; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="spore germination cortex-lytic enzyme" /protein_id="NP_390174.1" /db_xref="EnsemblGenomes-Gn:BSU22930" /db_xref="EnsemblGenomes-Tr:CAB14209" /db_xref="GOA:P50739" /db_xref="InterPro:IPR002477" /db_xref="InterPro:IPR011105" /db_xref="InterPro:IPR014224" /db_xref="InterPro:IPR036365" /db_xref="InterPro:IPR036366" /db_xref="SubtiList:BG11439" /db_xref="UniProtKB/Swiss-Prot:P50739" /translation="MKSKGSIMACLILFSFTITTFINTETISAFSNQVIQRGATGDDV VELQARLQYNGYYNGKIDGVYGWGTYWAVRNFQDQFGLKEVDGLVGAKTKQTLICKSK YYREYVMEQLNKGNTFTHYGKIPLKYQTKPSKAATQKARQQAEARQKQPAEKTTQKPK ANANKQQNNTPAKARKQDAVAANMPGGFSNNDIRLLAQAVYGEARGEPYEGQVAIAAV ILNRLNSPLFPNSVAGVIFEPLAFTAVADGQIYMQPNETAREAVLDAINGWDPSEEAL YYFNPDTATSPWIWGRPQIKRIGKHIFCE*" gene complement(2264750..2265667) /gene="sleB" /locus_tag="BSU_22930" /old_locus_tag="BSU22930" downshifts complement(2265138) /Source="Nicolas_upshifts" /id="D1197" /incds=1 /nref=1 /ntot=3 /MaxReadThrough="6.35344" /MaxDrop="4.29326" /score="-3.16364421" /energy="-21.7" /TU="U1791,U1792" /idTUdmin="U1793" /TUdmin=682 /isTUend="FALSE" misc_feature complement(2265289..2265296) /Source="Nicolas_upshift_promotors" /id="U1791" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.245754245754246" /psig="0.374625374625375" /xcortree=1472 /SigmaFactorBS="gaatatgtcatggaacagctcaataaagggaatacattcacg cattacggaaaaatTCCGCTAAagtatcagacgaaaccatcaaaagcagcaacacaaa a" /listShort="ypeB" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(2265292) /Source="Nicolas_upshifts" /id="U1791" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.245754245754246" /psig="0.374625374625375" /xcortree=1472 /SigmaFactorBS="gaatatgtcatggaacagctcaataaagggaatacattcacg cattacggaaaaatTCCGCTAAagtatcagacgaaaccatcaaaagcagcaacacaaa a" /listShort="ypeB" /GFF_Attribute="listLong" promotor_-10 complement(2265705..2265716) /Source="Nicolas_upshift_promotors" /id="U1792" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=937 /SigmaFactorBS="gtgcagtttttatgttctgagggataacaaggaaagagTGTA TAAaaataacctcgttACAGAAAATACGattacacttaaaaatttgcagtaggaggct t" /listShort="sleB, ypeB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2265714) /Source="Nicolas_upshifts" /id="U1792" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=937 /SigmaFactorBS="gtgcagtttttatgttctgagggataacaaggaaagagTGTA TAAaaataacctcgttACAGAAAATACGattacacttaaaaatttgcagtaggaggct t" /listShort="sleB, ypeB" /GFF_Attribute="listLong" promotor_-35 complement(2265730..2265736) /Source="Nicolas_upshift_promotors" /id="U1792" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=937 /SigmaFactorBS="gtgcagtttttatgttctgagggataacaaggaaagagTGTA TAAaaataacctcgttACAGAAAATACGattacacttaaaaatttgcagtaggaggct t" /listShort="sleB, ypeB" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2265806..2266462) /gene="prsW" /locus_tag="BSU_22940" /old_locus_tag="BSU22940" /EC_number="3.4.-.-" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:15849754, 16816000, 16850406, 17020587, 19889088, 23155385, 28674070" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15849754, 16816000, 16850406, 17020587, 19889088, 23155385, 28674070; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="protease required for RsiW anti-sigma(W) degradation" /protein_id="NP_390175.1" /db_xref="EnsemblGenomes-Gn:BSU22940" /db_xref="EnsemblGenomes-Tr:CAB14210" /db_xref="GOA:P50738" /db_xref="InterPro:IPR023596" /db_xref="InterPro:IPR026898" /db_xref="SubtiList:BG11438" /db_xref="UniProtKB/Swiss-Prot:P50738" /translation="MFAIISAGIAPGIALLSYFYLKDQYDNEPVHMVLRSFFLGVVLV FPIMFIQYVLEKENVGGGSFFVSFLSSGFLEESLKWFILMISVYPHAHFDEHYDGIVY GASVSLGFATLENILYLIGHGVEHAFVRALLPVSCHALIGVIMGFYLGKARFSADKAR VKWLTLSLVVPSLLHGSYDFILTALSNWIYYMLPFMVFLWWFGLRKAKKARSVNMMQV *" gene complement(2265806..2266462) /gene="prsW" /locus_tag="BSU_22940" /old_locus_tag="BSU22940" downshifts complement(2265820) /Source="Nicolas_upshifts" /id="D1198" /incds=0 /nref=239 /ntot=262 /MaxReadThrough="0.9181" /MaxDrop="6.61797" /score="-3.16364421" /energy="-21.7" /TU="NA" /idTUdmin="U1793" /TUdmin=0 /isTUend="TRUE" misc_feature complement(2266487..2266506) /Source="Nicolas_upshift_promotors" /id="U1793" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.976023976023976" /psig=1 /xcortree=3121 /SigmaFactorBS="cattcgtatgctctttttgtttttttaagtgcagacagatgt aaaattttaaacaaCATGGTAGGATAGATGTAGGaatataaaggaaagaggttgcctg a" /listShort="prsW" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(2266502) /Source="Nicolas_upshifts" /id="U1793" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.976023976023976" /psig=1 /xcortree=3121 /SigmaFactorBS="cattcgtatgctctttttgtttttttaagtgcagacagatgt aaaattttaaacaaCATGGTAGGATAGATGTAGGaatataaaggaaagaggttgcctg a" /listShort="prsW" /GFF_Attribute="listLong" CDS complement(2266582..2267556) /gene="ypdA" /locus_tag="BSU_22950" /old_locus_tag="BSU22950" /EC_number="1.8.-.-" /function="16.6: Maintain" /function="16.8: Protect" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 20308541; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative bacillithiol biosynthesis thiol disulfide oxidoreductase" /protein_id="NP_390176.2" /db_xref="EnsemblGenomes-Gn:BSU22950" /db_xref="EnsemblGenomes-Tr:CAB14211" /db_xref="GOA:P50736" /db_xref="InterPro:IPR000103" /db_xref="InterPro:IPR023856" /db_xref="InterPro:IPR036188" /db_xref="SubtiList:BG11436" /db_xref="UniProtKB/Swiss-Prot:P50736" /translation="MIQEKAIIIGGGPCGLSAAIHLKQIGIDALVIEKGNVVNSIYNY PTHQTFFSSSEKLEIGDVAFITENRKPVRIQALSYYREVVKRKNIRVNAFEMVRKVTK TQNNTFVIETSKETYTTPYCIIATGYYDHPNYMGVPGEDLPKVFHYFKEGHPYFDKDV VVIGGKNSSVDAALELVKSGARVTVLYRGNEYSPSIKPWILPEFEALVRNGTIRMEFG ACVEKITENEVVFRSGEKELITIKNDFVFAMTGYHPDHQFLEKIGVEIDKETGRPFFN EETMETNVEGVFIAGVIAAGNNANEIFIENGRFHGGHIAAEIAKRENH*" gene complement(2266582..2267556) /gene="ypdA" /locus_tag="BSU_22950" /old_locus_tag="BSU22950" downshifts complement(2266590) /Source="Nicolas_upshifts" /id="D1199" /incds=0 /nref=239 /ntot=263 /MaxReadThrough="3.524" /MaxDrop="6.45954" /score="27.4058676" /energy="-12.2" /TU="U1796" /idTUdmin="U1796" /TUdmin="-748" /isTUend="FALSE" promotor_-35 2267410..2267415 /Source="Nicolas_upshift_promotors" /id="U1794" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.958041958041958" /psig="0.958041958041958" /xcortree=1114 /SigmaFactorBS="atttcgagcttttcacttgaactgaaaaaGGTTTGatgcgtc gggtaattGTAAATACTGTTAACGACAttgcctttttcgatgacgagggcatcaatgc c" /listShort="S869" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2267431..2267449 /Source="Nicolas_upshift_promotors" /id="U1794" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.958041958041958" /psig="0.958041958041958" /xcortree=1114 /SigmaFactorBS="atttcgagcttttcacttgaactgaaaaaGGTTTGatgcgtc gggtaattGTAAATACTGTTAACGACAttgcctttttcgatgacgagggcatcaatgc c" /listShort="S869" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 2267441..2267634 /Source="Nicolas_S_feature" /locus_tag="new_2401843_2402036" /HighExp="S8, S6, S7, S4, S5, C30, S3, BT, B36, C90" /AntisenseName="ypdA" /AntisenseCor="-0.487730736536516" /AntisenseRegPval="-16.8" /CDS_PredictionProba="NA" /TUshortSig="SigEF" /TUshortPSig="0.958" /TUlongSig="NA" /TUlongPSig="NA" /label="S869" upshifts 2267441 /Source="Nicolas_upshifts" /id="U1794" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.958041958041958" /psig="0.958041958041958" /xcortree=1114 /SigmaFactorBS="atttcgagcttttcacttgaactgaaaaaGGTTTGatgcgtc gggtaattGTAAATACTGTTAACGACAttgcctttttcgatgacgagggcatcaatgc c" /listShort="S869" /GFF_Attribute="listLong" downshifts 2267592 /Source="Nicolas_upshifts" /id="D1200" /incds=0 /nref=13 /ntot=27 /MaxReadThrough="1.93985" /MaxDrop="5.69954" /score="23.7306175" /energy="-9.3" /TU="NA" /idTUdmin="U1794" /TUdmin=0 /isTUend="TRUE" CDS complement(2267665..2268948) /gene="gudB" /locus_tag="BSU_22960" /old_locus_tag="BSU22960" /EC_number="1.4.1.2" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:9829940, 18326565, 22178969, 22720735, 25610436" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9829940, 18326565, 22178969, 22720735, 25610436; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="cryptic glutamate dehydrogenase (active after removal of a 9 bp insert)" /protein_id="NP_390177.2" /db_xref="EnsemblGenomes-Gn:BSU22960" /db_xref="EnsemblGenomes-Tr:CAB14212" /db_xref="GOA:P50735" /db_xref="InterPro:IPR006095" /db_xref="InterPro:IPR006096" /db_xref="InterPro:IPR006097" /db_xref="InterPro:IPR014362" /db_xref="InterPro:IPR033524" /db_xref="InterPro:IPR033922" /db_xref="InterPro:IPR036291" /db_xref="PDB:3K8Z" /db_xref="SubtiList:BG11435" /db_xref="UniProtKB/Swiss-Prot:P50735" /translation="MAADRNTGHTEEDKLDVLKSTQTVIHKALEKLGYPEEVYELLKE PMRLLTVKIPVRMDDGSVKIFTGYRAQHNDSVGPTKGGIRFHPNVTEKEVKAVKALSI WMSLKCGIIDLPYGGGKGGIVCDPRDMSFRELERLSRGYVRAISQIVGPTKDVPAPDV FTNSQIMAWMMDEYSRIDEFNSPGFITGKPLVLGGSHGRESATAKGVTICIKEAAKKR GIDIKGARVVVQGFGNAGSYLAKFMHDAGAKVVGISDAYGGLYDPEGLDIDYLLDRRD SFGTVTKLFNDTITNQELLELDCDILVPAAIENQITEENAHNIRAKIVVEAANGPTTL EGTKILSDRDILLVPDVLASAGGVTVSYFEWVQNNQGFYWSEEEVEEKLEKMMVKSFN NIYEMANNRRIDMRLAAYMVGVRKMAEASRFRGWI*" gene complement(2267665..2268948) /gene="gudB" /locus_tag="BSU_22960" /old_locus_tag="BSU22960" downshifts complement(2267668) /Source="Nicolas_upshifts" /id="D1201" /incds=0 /nref=2 /ntot=54 /MaxReadThrough="7.92262" /MaxDrop="4.04542" /score="18.1400723" /energy="-9.3" /TU="U1796" /idTUdmin="U1797" /TUdmin=1345 /isTUend="FALSE" promotor_-35 2267706..2267712 /Source="Nicolas_upshift_promotors" /id="U1795" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.965034965034965" /psig="0.001998001998002" /xcortree=59 /SigmaFactorBS="cttatatccagcctctaaaacgcgaagcttcagccattttgc GAACGCCgaccatatatgCAGCGagcctcatgtcaattcttcggttgttagccatttc g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2267724..2267728 /Source="Nicolas_upshift_promotors" /id="U1795" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.965034965034965" /psig="0.001998001998002" /xcortree=59 /SigmaFactorBS="cttatatccagcctctaaaacgcgaagcttcagccattttgc GAACGCCgaccatatatgCAGCGagcctcatgtcaattcttcggttgttagccatttc g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2267724 /Source="Nicolas_upshifts" /id="U1795" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.965034965034965" /psig="0.001998001998002" /xcortree=59 /SigmaFactorBS="cttatatccagcctctaaaacgcgaagcttcagccattttgc GAACGCCgaccatatatgCAGCGagcctcatgtcaattcttcggttgttagccatttc g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 complement(2268991..2269010) /Source="Nicolas_upshift_promotors" /id="U1796" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.716283716283716" /psig="0.972027972027972" /xcortree=2225 /SigmaFactorBS="ttttttttcgttaaaaaacatggaaaaacataacgtttatTC TATGCAcagatcatatgaagGTGTATACTATTCTCTGAAAgggagcatgtgagaaaca g" /listShort="gudB, ypdA, prsW" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2269012) /Source="Nicolas_upshifts" /id="U1796" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.716283716283716" /psig="0.972027972027972" /xcortree=2225 /SigmaFactorBS="ttttttttcgttaaaaaacatggaaaaacataacgtttatTC TATGCAcagatcatatgaagGTGTATACTATTCTCTGAAAgggagcatgtgagaaaca g" /listShort="gudB, ypdA, prsW" /GFF_Attribute="listLong" promotor_-35 complement(2269025..2269032) /Source="Nicolas_upshift_promotors" /id="U1796" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.716283716283716" /psig="0.972027972027972" /xcortree=2225 /SigmaFactorBS="ttttttttcgttaaaaaacatggaaaaacataacgtttatTC TATGCAcagatcatatgaagGTGTATACTATTCTCTGAAAgggagcatgtgagaaaca g" /listShort="gudB, ypdA, prsW" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2269104..2269688) /gene="mecB" /locus_tag="BSU_22970" /old_locus_tag="BSU22970" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:11914365, 19801546" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11914365, 19801546; Product type f: factor" /codon_start=1 /transl_table=11 /product="adaptor to ClpC; regulator of competence and sporulation" /protein_id="NP_390178.1" /db_xref="EnsemblGenomes-Gn:BSU22970" /db_xref="EnsemblGenomes-Tr:CAB14213" /db_xref="GOA:P50734" /db_xref="InterPro:IPR008681" /db_xref="PDB:3JTN" /db_xref="PDB:3JTO" /db_xref="SubtiList:BG11434" /db_xref="UniProtKB/Swiss-Prot:P50734" /translation="MRLERLNYNKIKIFLTLDDLTDRGLTKEDLWKDSFKVHQLFKDM MNEANTELGFEANGPIAVEVYSLQAQGMVVIVTKNQDADSEDDEYDDDYIEMQVKLDE SADIIYQFHSFEDIIQLSESLQRIGITGGTVYHYDGQYFLSLEDLGSHTAEGVVAVLA EYGNPTTLTIYRLQEYGKLIMDGNAVETIQTHFS*" gene complement(2269104..2269688) /gene="mecB" /locus_tag="BSU_22970" /old_locus_tag="BSU22970" downshifts complement(2269106) /Source="Nicolas_upshifts" /id="D1202" /incds=0 /nref=258 /ntot=274 /MaxReadThrough="3.02006" /MaxDrop="7.92719" /score="23.8885529" /energy="-7.1" /TU="U1797" /idTUdmin="U1797" /TUdmin="-93" /isTUend="FALSE" S_feature complement(2269689..2269770) /Source="Nicolas_S_feature" /locus_tag="new_2404091_2404172_c" /HighExp="dia5, Diami, Etha, dia15, C90, Salt, LPhT, Heat, MG-0.2, Lbtran" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="SigWXY" /TUlongPSig=1 /label="S870" promotor_-10 complement(2269763..2269782) /Source="Nicolas_upshift_promotors" /id="U1797" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.846153846153846" /psig=1 /xcortree=638 /SigmaFactorBS="atccgtatggcaataaaaactgcattgTGCTTGTCttactag tgaactCAGTGTAAACTGATAACAATtaagaacctatgactcatcatctcatataatg t" /listShort="S870, mecB" /listLong="gudB, ypdA" /label="promotor_-10" upshifts complement(2269770) /Source="Nicolas_upshifts" /id="U1797" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.846153846153846" /psig=1 /xcortree=638 /SigmaFactorBS="atccgtatggcaataaaaactgcattgTGCTTGTCttactag tgaactCAGTGTAAACTGATAACAATtaagaacctatgactcatcatctcatataatg t" /listShort="S870, mecB" /listLong="gudB, ypdA" promotor_-35 complement(2269796..2269803) /Source="Nicolas_upshift_promotors" /id="U1797" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.846153846153846" /psig=1 /xcortree=638 /SigmaFactorBS="atccgtatggcaataaaaactgcattgTGCTTGTCttactag tgaactCAGTGTAAACTGATAACAATtaagaacctatgactcatcatctcatataatg t" /listShort="S870, mecB" /listLong="gudB, ypdA" /label="promotor_-35" CDS complement(2269847..2270626) /gene="ypbG" /locus_tag="BSU_22980" /old_locus_tag="BSU22980" /EC_number="3.1.-.-" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15838020, 17434969; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative phosphoesterase" /protein_id="NP_390179.1" /db_xref="EnsemblGenomes-Gn:BSU22980" /db_xref="EnsemblGenomes-Tr:CAB14214" /db_xref="GOA:P50733" /db_xref="InterPro:IPR004843" /db_xref="InterPro:IPR029052" /db_xref="SubtiList:BG11433" /db_xref="UniProtKB/Swiss-Prot:P50733" /translation="MKLSVKIAGVLTVAAAAMTAKMYATAKGNHLKTHTFPLSKMKGK PPLTIFFISDIHKRLIDQDLLEKARSHAPHLVIIGGDLAEGGVPSARIEENIKRLVHF GVPIVFVWGNNDYEVRQHKLYSIFKAHGVITLRNESVPFSYNGHTIAIAGVDDIRMEM DHYEEAIKELDESQLNILVCHNPEIHEQINEDDGIDVILSGHTHGGQIRFGKFGPYEL GKTGIVKNAAYLISNGYGTTKVPLRLGAEPETHIVTLCGPE*" gene complement(2269847..2270626) /gene="ypbG" /locus_tag="BSU_22980" /old_locus_tag="BSU22980" promotor_-10 complement(2270652..2270667) /Source="Nicolas_upshift_promotors" /id="U1798" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1649 /SigmaFactorBS="gaaagtaaataaaatggggcgttttctcaaacgatAGAAACG TCTttttttattgtCCGTCTTATTGATAAGttctaaaaagaatggagagttttttatg a" /listShort="ypbG" /listLong="S870, mecB" /label="promotor_-10" upshifts complement(2270663) /Source="Nicolas_upshifts" /id="U1798" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1649 /SigmaFactorBS="gaaagtaaataaaatggggcgttttctcaaacgatAGAAACG TCTttttttattgtCCGTCTTATTGATAAGttctaaaaagaatggagagttttttatg a" /listShort="ypbG" /listLong="S870, mecB" promotor_-35 complement(2270679..2270688) /Source="Nicolas_upshift_promotors" /id="U1798" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1649 /SigmaFactorBS="gaaagtaaataaaatggggcgttttctcaaacgatAGAAACG TCTttttttattgtCCGTCTTATTGATAAGttctaaaaagaatggagagttttttatg a" /listShort="ypbG" /listLong="S870, mecB" /label="promotor_-35" CDS complement(2270712..2271155) /gene="ypbF" /locus_tag="BSU_22990" /old_locus_tag="BSU22990" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_390180.1" /db_xref="EnsemblGenomes-Gn:BSU22990" /db_xref="EnsemblGenomes-Tr:CAB14215" /db_xref="GOA:P50732" /db_xref="InterPro:IPR020210" /db_xref="SubtiList:BG11432" /db_xref="UniProtKB/Swiss-Prot:P50732" /translation="MESLWNQLDQFTDAPTKQMLQALVKRKQKFENYAAQCRRWRWAS LICLGLLCVMIMIKSPEPQLILQEILSHTFYLFWMLATAFAYCTSYYFKKKEEKSETD FHKLRCEIIQKSTDLWPQPDKWKARESVFHMMKHKYDINLYFESK*" gene complement(2270712..2271155) /gene="ypbF" /locus_tag="BSU_22990" /old_locus_tag="BSU22990" downshifts complement(2270729) /Source="Nicolas_upshifts" /id="D1203" /incds=0 /nref=4 /ntot=112 /MaxReadThrough="4.67294" /MaxDrop="3.33254" /score="6.86206051" /energy="-7.5" /TU="U1801" /idTUdmin="U1799" /TUdmin=22 /isTUend="TRUE" CDS complement(2271218..2271940) /gene="ypbE" /locus_tag="BSU_23000" /old_locus_tag="BSU23000" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 16855244, 22950025; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative enzyme possibly involved in cell wall turnover" /protein_id="NP_390181.1" /db_xref="EnsemblGenomes-Gn:BSU23000" /db_xref="EnsemblGenomes-Tr:CAB14216" /db_xref="GOA:P50731" /db_xref="InterPro:IPR018392" /db_xref="InterPro:IPR036779" /db_xref="SubtiList:BG11431" /db_xref="UniProtKB/Swiss-Prot:P50731" /translation="MTNMSRVERRKAQNLYEDQNAALADDYVDDGESLPTRQSVKNQR EQKKKQGKTKTPLFTVLAVIFVFVPVIVLVTLFYLKSHPDNHDDYEDVFIDSSQSKYE VVPKSEDKNDTADTKETALQKESKKEPEDSKPKEQTAADKKQTAVAEKEDSPNKEEAT AAAASSSQSTVQQQEQPAEPVQNVPNRVVKHTVQKKETLYRISMKYYKSRTGEEKIRA YNHLNGNDVYTGQVLDIPLMDE*" gene complement(2271218..2271940) /gene="ypbE" /locus_tag="BSU_23000" /old_locus_tag="BSU23000" downshifts complement(2271499) /Source="Nicolas_upshifts" /id="D1204" /incds=1 /nref=4 /ntot=93 /MaxReadThrough="4.30678" /MaxDrop="3.33147" /score="6.86206051" /energy="-7.5" /TU="U1799,U1801" /idTUdmin="U1799" /TUdmin="-748" /isTUend="FALSE" CDS complement(2271891..2272460) /gene="ypbD" /locus_tag="BSU_23010" /old_locus_tag="BSU23010" /function="16.6: Maintain" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 15849754, 16850406" /codon_start=1 /transl_table=11 /product="conserved membrane protein of unknown function" /protein_id="NP_390182.1" /db_xref="EnsemblGenomes-Gn:BSU23010" /db_xref="EnsemblGenomes-Tr:CAB14217" /db_xref="GOA:P50730" /db_xref="InterPro:IPR003675" /db_xref="SubtiList:BG11430" /db_xref="UniProtKB/Swiss-Prot:P50730" /translation="MTQLLIIFAAAAAGLFFFEDVRDVLKLWDIRDMRIIWYGVSIAV IVILADMAVMKWFPSHLYDDGGINKKIFSKRSIPHIIFLTLLIAFAEEMLFRGVLQTH IGLWTASLIFAALHFRYLSKWLLFIMVTAISFLLGLMYEWTGNLFVPMTAHFIIDAVF ACQIRFEHVRRDKHDEHVESREKKSPESL*" gene complement(2271891..2272460) /gene="ypbD" /locus_tag="BSU_23010" /old_locus_tag="BSU23010" promotor_-10 complement(2272209..2272227) /Source="Nicolas_upshift_promotors" /id="U1799" /multdbtbs="-" /comp="M3" /sig="Sig-" /pcomp="0.466533466533467" /psig="0.466533466533467" /xcortree=1458 /SigmaFactorBS="ctcatttatatgatgacggcggaatcaataaaaaaatATTCA GTaagaggtcaatcccTCATATTATATTTTTAACGcttctgattgctttcgcggaaga a" /listShort="ypbE, ypbF" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2272225) /Source="Nicolas_upshifts" /id="U1799" /multdbtbs="-" /comp="M3" /sig="Sig-" /pcomp="0.466533466533467" /psig="0.466533466533467" /xcortree=1458 /SigmaFactorBS="ctcatttatatgatgacggcggaatcaataaaaaaatATTCA GTaagaggtcaatcccTCATATTATATTTTTAACGcttctgattgctttcgcggaaga a" /listShort="ypbE, ypbF" /GFF_Attribute="listLong" promotor_-35 complement(2272242..2272248) /Source="Nicolas_upshift_promotors" /id="U1799" /multdbtbs="-" /comp="M3" /sig="Sig-" /pcomp="0.466533466533467" /psig="0.466533466533467" /xcortree=1458 /SigmaFactorBS="ctcatttatatgatgacggcggaatcaataaaaaaatATTCA GTaagaggtcaatcccTCATATTATATTTTTAACGcttctgattgctttcgcggaaga a" /listShort="ypbE, ypbF" /GFF_Attribute="listLong" /label="promotor_-35" S_feature 2272479..2273225 /Source="Nicolas_S_feature" /locus_tag="new_2406881_2407627" /HighExp="S6, S8, S7, C30, BT, S5, C90, Pyr, BC, Sw" /AntisenseName="recQ" /AntisenseCor="-0.47918253719211501" /AntisenseRegPval="-16.100000000000001" /CDS_PredictionProba="NA" /TUshortSig="NA" /TUshortPSig="NA" /TUlongSig="NA" /TUlongPSig="NA" /label="S871" CDS complement(2272520..2274010) /gene="recS" /locus_tag="BSU_23020" /old_locus_tag="BSU23020" /EC_number="3.6.1.-" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:16385024, 25246477, 26001966, 28527403" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16385024, 25246477, 26001966, 28527403; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="ATP-dependent DNA helicase" /protein_id="NP_390183.1" /db_xref="EnsemblGenomes-Gn:BSU23020" /db_xref="EnsemblGenomes-Tr:CAB14218" /db_xref="GOA:P50729" /db_xref="InterPro:IPR001650" /db_xref="InterPro:IPR002464" /db_xref="InterPro:IPR004589" /db_xref="InterPro:IPR011545" /db_xref="InterPro:IPR014001" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG11407" /db_xref="UniProtKB/Swiss-Prot:P50729" /translation="MTKLQQTLYQFFGFTSFKKGQQDIIESILSGKDTIAMLPTGGGK SLCYQLPGYMLDGMVLIVSPLLSLMEDQVQQLKARGEKRAAALNSMLNRQERQFVLEH IHRYKFLYLSPEALQSPYVLEKLKSVPISLFVIDEAHCISEWGHDFRPDYSKLGQLRK KLGHPPVLALTATATKETLQDVMNLLELQHAVRHLNSVNRPNIALRVENAADTAEKID RVIQLVENLQGPGIVYCPTRKWAKELAGEIKSKTSSRADFYHGGLESGDRILIQQQFI HNQLDVICCTNAFGMGVDKPDIRYVIHFHLPQTAEAFMQEIGRAGRDGKPSVSILLRA PGDFELQEQIIQMESVTAEEIADVIRVLEKTEERDERRLRDVLLQYGVGETQARMMIH LFMQGKTSVELMKKEISYRMELKLEKMHRVSFLLQRDGCLRQALLTYFDESYEPDDGN LPCCSHCGFDLSLYEQKGERSKMAPLDSWSSELHRIFSLQTVGELN*" gene complement(2272520..2274010) /gene="recS" /locus_tag="BSU_23020" /old_locus_tag="BSU23020" CDS complement(2274003..2275061) /gene="gmmB" /locus_tag="BSU_23030" /old_locus_tag="BSU23030" /experiment="publication(s) with functional evidences, PMID:21170359" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 21170359; Product type f: factor" /codon_start=1 /transl_table=11 /product="subunit of the platform for genome maintenance machinery" /protein_id="NP_390184.1" /db_xref="EnsemblGenomes-Gn:BSU23030" /db_xref="EnsemblGenomes-Tr:CAB14219" /db_xref="InterPro:IPR008308" /db_xref="InterPro:IPR029491" /db_xref="InterPro:IPR036388" /db_xref="SubtiList:BG11429" /db_xref="UniProtKB/Swiss-Prot:P50728" /translation="MSLNYFDIMVLDCLCKINGERSGSAVFHLFKGKRSSQTIQDAGL FQTAKYFGMAAKCSRSDISASLDKLEKHSYLAPMSESDTYKVTASGAAVLRHALSERP WPVHCHGAHYQQAAGVLWKRLSLLVQVLSHKQQGSRQYIPVTKDHKTLHWVKKYLSRH TDHIEMAKSLFAMLEAHLKKIENKAAQIFVYSLTSHHRIGYTSRQLADTLKEDEWYVY IMFWASVHYFIHSLPECEDALLKDLLSDVHLDNALTESTRKTWQMVKQGFPIQRIAEI RKLKTATIEDHIVEISLHEPAFMINDYVSAEDQLQIAEFAKRMRTNKIKQIRDGLEQR FSYFQIRLALTKQVQQYD*" gene complement(2274003..2275061) /gene="gmmB" /locus_tag="BSU_23030" /old_locus_tag="BSU23030" promotor_-35 2274351..2274360 /Source="Nicolas_upshift_promotors" /id="U1800" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.996003996003996" /psig="0.996003996003996" /xcortree=1318 /SigmaFactorBS="tatctaagtgcacatcagaaaggagatcctttaacaaagcAT CTTCACACtccggaagagaaTGAATAAAATAATGTACCGAagcccaaaacatgatata g" /listShort="S872, S873, S874, fer" /GFF_Attribute="listLong" /label="promotor_-35" S_feature 2274371..2275161 /Source="Nicolas_S_feature" /locus_tag="new_2408773_2409563" /HighExp="S8, S6, S7, S5, BT, B36, Pyr, G/S, B60, nit" /AntisenseName="ypbB" /AntisenseCor="-0.76734368116597995" /AntisenseRegPval="-52.7" /CDS_PredictionProba="NA" /TUshortSig="SigK" /TUshortPSig="0.996" /TUlongSig="NA" /TUlongPSig="NA" /label="S872" upshifts 2274371 /Source="Nicolas_upshifts" /id="U1800" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.996003996003996" /psig="0.996003996003996" /xcortree=1318 /SigmaFactorBS="tatctaagtgcacatcagaaaggagatcctttaacaaagcAT CTTCACACtccggaagagaaTGAATAAAATAATGTACCGAagcccaaaacatgatata g" /listShort="S872, S873, S874, fer" /GFF_Attribute="listLong" promotor_-10 2274373..2274392 /Source="Nicolas_upshift_promotors" /id="U1800" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.996003996003996" /psig="0.996003996003996" /xcortree=1318 /SigmaFactorBS="tatctaagtgcacatcagaaaggagatcctttaacaaagcAT CTTCACACtccggaagagaaTGAATAAAATAATGTACCGAagcccaaaacatgatata g" /listShort="S872, S873, S874, fer" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-10 complement(2275102..2275121) /Source="Nicolas_upshift_promotors" /id="U1801" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.926073926073926" /psig="0.993006993006993" /xcortree=2277 /SigmaFactorBS="ataaggggttatctacataacatcccccttaatgatgacttt aaaCGTCGATTtctgtttgaaaTCTGTTAAAATAAAAAGAGCaaatcaacgatttttg t" /listShort="ypbB, recQ, ypbD, ypbE, ypbF, ypbG" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2275125) /Source="Nicolas_upshifts" /id="U1801" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.926073926073926" /psig="0.993006993006993" /xcortree=2277 /SigmaFactorBS="ataaggggttatctacataacatcccccttaatgatgacttt aaaCGTCGATTtctgtttgaaaTCTGTTAAAATAAAAAGAGCaaatcaacgatttttg t" /listShort="ypbB, recQ, ypbD, ypbE, ypbF, ypbG" /GFF_Attribute="listLong" promotor_-35 complement(2275133..2275140) /Source="Nicolas_upshift_promotors" /id="U1801" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.926073926073926" /psig="0.993006993006993" /xcortree=2277 /SigmaFactorBS="ataaggggttatctacataacatcccccttaatgatgacttt aaaCGTCGATTtctgtttgaaaTCTGTTAAAATAAAAAGAGCaaatcaacgatttttg t" /listShort="ypbB, recQ, ypbD, ypbE, ypbF, ypbG" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 2275139..2275145 /Source="Nicolas_upshift_promotors" /id="U1802" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.99100899100899" /psig="0.99100899100899" /xcortree=115 /SigmaFactorBS="ctctttttattttaacagatttcaaacagaaatcgaCGTTTA AagtcatcattaagGGGGATGTTATGTAGATAACcccttatgtgataagcattctcaa t" /listShort="S873" /listLong="S874, fer" /label="promotor_-35" promotor_-10 2275159..2275178 /Source="Nicolas_upshift_promotors" /id="U1802" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.99100899100899" /psig="0.99100899100899" /xcortree=115 /SigmaFactorBS="ctctttttattttaacagatttcaaacagaaatcgaCGTTTA AagtcatcattaagGGGGATGTTATGTAGATAACcccttatgtgataagcattctcaa t" /listShort="S873" /listLong="S874, fer" /label="promotor_-10" S_feature 2275163..2275232 /Source="Nicolas_S_feature" /locus_tag="new_2409565_2409634" /HighExp="S6, S8, S7, S5, BT, B36, C30, Pyr, B60, G/S" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigB, SigK" /TUshortPSig="0.991, 0.996" /TUlongSig="NA" /TUlongPSig="NA" /label="S873" upshifts 2275163 /Source="Nicolas_upshifts" /id="U1802" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.99100899100899" /psig="0.99100899100899" /xcortree=115 /SigmaFactorBS="ctctttttattttaacagatttcaaacagaaatcgaCGTTTA AagtcatcattaagGGGGATGTTATGTAGATAACcccttatgtgataagcattctcaa t" /listShort="S873" /listLong="S874, fer" promotor_-35 2275212..2275219 /Source="Nicolas_upshift_promotors" /id="U1803" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.692307692307692" /psig=1 /xcortree=1751 /SigmaFactorBS="ataaccccttatgtgataagcattctcaatcatttttcTGTT GAAAtgtggcagcaacatCATTACAATAAGTAAGAGGAataggtgttaaattgattaa a" /listShort="S874, fer" /GFF_Attribute="listLong" /label="promotor_-35" S_feature 2275234..2275326 /Source="Nicolas_S_feature" /locus_tag="new_2409636_2409728" /HighExp="LPhT, LBGstat, HPh, C90, LBGtran, C30, Lbtran, Cold, LPh, MG 25" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigK" /TUshortPSig="1, 0.996" /TUlongSig="SigB" /TUlongPSig="0.991" /label="S874" promotor_-10 2275234..2275253 /Source="Nicolas_upshift_promotors" /id="U1803" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.692307692307692" /psig=1 /xcortree=1751 /SigmaFactorBS="ataaccccttatgtgataagcattctcaatcatttttcTGTT GAAAtgtggcagcaacatCATTACAATAAGTAAGAGGAataggtgttaaattgattaa a" /listShort="S874, fer" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2275234 /Source="Nicolas_upshifts" /id="U1803" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.692307692307692" /psig=1 /xcortree=1751 /SigmaFactorBS="ataaccccttatgtgataagcattctcaatcatttttcTGTT GAAAtgtggcagcaacatCATTACAATAAGTAAGAGGAataggtgttaaattgattaa a" /listShort="S874, fer" /GFF_Attribute="listLong" CDS 2275327..2275575 /gene="fer" /locus_tag="BSU_23040" /old_locus_tag="BSU23040" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:12538057, 21665975" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12538057, 21665975; Product type c: carrier" /codon_start=1 /transl_table=11 /product="ferredoxin" /protein_id="NP_390185.1" /db_xref="EnsemblGenomes-Gn:BSU23040" /db_xref="EnsemblGenomes-Tr:CAB14220" /db_xref="GOA:P50727" /db_xref="InterPro:IPR001080" /db_xref="InterPro:IPR017896" /db_xref="SubtiList:BG11388" /db_xref="UniProtKB/Swiss-Prot:P50727" /translation="MAKYTIVDKDTCIACGACGAAAPDIYDYDDEGIAFVTLDENKGV VEVPEVLEEDMIDAFEGCPTDSIKVADEPFEGDPLKFE*" gene 2275327..2275575 /gene="fer" /locus_tag="BSU_23040" /old_locus_tag="BSU23040" downshifts 2275559 /Source="Nicolas_upshifts" /id="D1205" /incds=0 /nref=221 /ntot=291 /MaxReadThrough="3.16016" /MaxDrop="8.38074" /score="34.9672707" /energy="-9.9" /TU="U1803" /idTUdmin="U1800" /TUdmin=0 /isTUend="TRUE" CDS complement(2275615..2276187) /gene="fmnP" /locus_tag="BSU_23050" /old_locus_tag="BSU23050" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:12456892, 15849754, 16850406, 17693491, 25438558" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12456892, 15849754, 16850406, 17693491, 25438558; Product type t : transporter" /codon_start=1 /transl_table=11 /product="FMN permease" /protein_id="NP_390186.1" /db_xref="EnsemblGenomes-Gn:BSU23050" /db_xref="EnsemblGenomes-Tr:CAB14237" /db_xref="GOA:P50726" /db_xref="InterPro:IPR024529" /db_xref="InterPro:IPR025720" /db_xref="SubtiList:BG11428" /db_xref="UniProtKB/Swiss-Prot:P50726" /translation="MKVKKLVVVSMLSSIAFVLMLLNFPFPGLPDYLKIDFSDVPAII AILIYGPLAGIAVEAIKNVLQYIIQGSMAGVPVGQVANFIAGTLFILPTAFLFKKLNS AKGLAVSLLLGTAAMTILMSILNYVLILPAYTWFLHSPALSDSALKTAVVAGILPFNM IKGIVITVVFSLIFIKLKPWIEQQRSAHIH*" gene complement(2275615..2276187) /gene="fmnP" /locus_tag="BSU_23050" /old_locus_tag="BSU23050" downshifts complement(2275635) /Source="Nicolas_upshifts" /id="D1206" /incds=0 /nref=103 /ntot=231 /MaxReadThrough="2.60651" /MaxDrop="4.95518" /score="35.0684207" /energy="-9.9" /TU="NA" /idTUdmin="U1804" /TUdmin=0 /isTUend="TRUE" misc_RNA complement(2276179..2276486) /gene="fswB" /locus_tag="BSU_misc_RNA_78" /product="flavin mononucleotide riboswitch" /experiment="publication(s) with functional evidences, PMID:12456892, 15808508" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12456892, 15808508; Product type n: RNA" gene complement(2276179..2276486) /gene="fswB" /locus_tag="BSU_misc_RNA_78" S_feature complement(2276188..2276292) /Source="Nicolas_S_feature" /locus_tag="new_2410590_2410694_c" /HighExp="S1, LPhT, M9-stat, B60, Heat, T0.30H, Gly, S5, BC, S7" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S875" promotor_-10 complement(2276485..2276504) /Source="Nicolas_upshift_promotors" /id="U1804" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.425574425574426" /psig=1 /xcortree=605 /SigmaFactorBS="acagcttgcaggtaatatatttaatttgaagcaattcTCTAT ACagccaaccagttaTCGTTTATAATGTAATTAAAtttcatatgatcaatcttcgggg c" /listShort="ypzE, S875, fmnP" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2276501) /Source="Nicolas_upshifts" /id="U1804" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.425574425574426" /psig=1 /xcortree=605 /SigmaFactorBS="acagcttgcaggtaatatatttaatttgaagcaattcTCTAT ACagccaaccagttaTCGTTTATAATGTAATTAAAtttcatatgatcaatcttcgggg c" /listShort="ypzE, S875, fmnP" /GFF_Attribute="listLong" promotor_-35 complement(2276518..2276524) /Source="Nicolas_upshift_promotors" /id="U1804" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.425574425574426" /psig=1 /xcortree=605 /SigmaFactorBS="acagcttgcaggtaatatatttaatttgaagcaattcTCTAT ACagccaaccagttaTCGTTTATAATGTAATTAAAtttcatatgatcaatcttcgggg c" /listShort="ypzE, S875, fmnP" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 2276613..2276620 /Source="Nicolas_upshift_promotors" /id="U1805" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.887112887112887" /psig="0.995004995004995" /xcortree=3067 /SigmaFactorBS="gatttattaggctttacttttatcctttactgcgtcaataca CGTTGACActcttttgagaataTGTTAAATTATCAGATATTTagtttgtcaatttagg a" /listShort="serA" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 2276631 /Source="Nicolas_upshifts" /id="U1805" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.887112887112887" /psig="0.995004995004995" /xcortree=3067 /SigmaFactorBS="gatttattaggctttacttttatcctttactgcgtcaataca CGTTGACActcttttgagaataTGTTAAATTATCAGATATTTagtttgtcaatttagg a" /listShort="serA" /GFF_Attribute="listLong" promotor_-10 2276635..2276654 /Source="Nicolas_upshift_promotors" /id="U1805" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.887112887112887" /psig="0.995004995004995" /xcortree=3067 /SigmaFactorBS="gatttattaggctttacttttatcctttactgcgtcaataca CGTTGACActcttttgagaataTGTTAAATTATCAGATATTTagtttgtcaatttagg a" /listShort="serA" /GFF_Attribute="listLong" /label="promotor_-10" CDS 2276684..2278261 /gene="serA" /locus_tag="BSU_23070" /old_locus_tag="BSU23070" /EC_number="1.1.1.95" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:168067, 11390694, 17611193, 4337849, 21749987, 22938038, 28827360" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 168067, 11390694, 17611193, 4337849, 21749987, 22938038, 28827360; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="3-phosphoglycerate dehydrogenase" /protein_id="NP_390188.2" /db_xref="EnsemblGenomes-Gn:BSU23070" /db_xref="EnsemblGenomes-Tr:CAB14239" /db_xref="GOA:P35136" /db_xref="InterPro:IPR002912" /db_xref="InterPro:IPR006139" /db_xref="InterPro:IPR006140" /db_xref="InterPro:IPR006236" /db_xref="InterPro:IPR029009" /db_xref="InterPro:IPR029752" /db_xref="InterPro:IPR029753" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG10509" /db_xref="UniProtKB/Swiss-Prot:P35136" /translation="MFRVLVSDKMSNDGLQPLIESDFIEIVQKNVADAEDELHTFDAL LVRSATKVTEDLFNKMTSLKIVGRAGVGVDNIDIDEATKHGVIVINAPNGNTISTAEH TFAMISSLMRHIPQANISVKSREWNRTAYVGSELYGKTLGIVGLGRIGSEIAQRARAF GMTVHVFDPFLTEERAKKIGVNSRTFEEVLESADIITVHTPLTKETKGLLNKETIAKT KKGVRLINCARGGIIDEAALLEALENGHVAGAALDVFEVEPPVDNKLVDHPLVIATPH LGASTKEAQLNVAAQVSEEVLQFAKGLPVMSAINLPAMTKDEFAKIKPYHQIAGKIGS LVSQCMKEPVQDVAIQYEGTIAKLETSFITKALLSGFLKPRVDSTVNEVNAGGVAKER GISFSEKISSSESGYDNCISVKVTGDRSTFTVTATYIPHFGERIVEINGFNIDFYPTG HLVYIQHQDTTGVIGRVGRILGDNDINIATMQVGRKEKGGEAIMMLSFDRHLEDKIVK ELTNVPDIVSVKLIDLP*" gene 2276684..2278261 /gene="serA" /locus_tag="BSU_23070" /old_locus_tag="BSU23070" downshifts 2278243 /Source="Nicolas_upshifts" /id="D1207" /incds=0 /nref=246 /ntot=311 /MaxReadThrough="3.23011" /MaxDrop="8.29454" /score="32.0086708" /energy="-10.2" /TU="U1805" /idTUdmin="U1805" /TUdmin="-198" /isTUend="FALSE" CDS complement(2278304..2279071) /gene="aroC" /locus_tag="BSU_23080" /old_locus_tag="BSU23080" /EC_number="4.2.1.10" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:6442253" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 6442253; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="3-dehydroquinate dehydratase" /protein_id="NP_390189.1" /db_xref="EnsemblGenomes-Gn:BSU23080" /db_xref="EnsemblGenomes-Tr:CAB14240" /db_xref="GOA:P35146" /db_xref="InterPro:IPR001381" /db_xref="InterPro:IPR013785" /db_xref="InterPro:IPR018508" /db_xref="SubtiList:BG10538" /db_xref="UniProtKB/Swiss-Prot:P35146" /translation="MNVLTIKGVSIGEGMPKIIIPLMGKTEKQILNEAEAVKLLNPDI VEWRVDVFEKANDREAVTKLISKLRKSLEDKLFLFTFRTHKEGGSMEMDESSYLALLE SAIQTKDIDLIDIELFSGDANVKALVSLAEENNVYVVMSNHDFEKTPVKDEIISRLRK MQDLGAHIPKMAVMPNDTGDLLTLLDATYTMKTIYADRPIITMSMAATGLISRLSGEV FGSACTFGAGEEASAPGQIPVSELRSVLDILHKNTRG*" gene complement(2278304..2279071) /gene="aroC" /locus_tag="BSU_23080" /old_locus_tag="BSU23080" downshifts complement(2278319) /Source="Nicolas_upshifts" /id="D1208" /incds=0 /nref=152 /ntot=231 /MaxReadThrough="2.53428" /MaxDrop="5.12103" /score="24.3727755" /energy="-10.2" /TU="NA" /idTUdmin="U1806" /TUdmin=0 /isTUend="TRUE" S_feature 2278573..2279185 /Source="Nicolas_S_feature" /locus_tag="new_2412975_2413587" /HighExp="B36, C30, LoTm, B60, C90, HiOs, BI, Sw, T1.0H, BT" /AntisenseName="aroC" /AntisenseCor="4.7354591214804703E-2" /AntisenseRegPval="-0.4" /CDS_PredictionProba="NA" /TUshortSig="NA" /TUshortPSig="NA" /TUlongSig="NA" /TUlongPSig="NA" /label="S876" promotor_-10 complement(2279098..2279117) /Source="Nicolas_upshift_promotors" /id="U1806" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.943056943056943" /psig=1 /xcortree=2283 /SigmaFactorBS="taaggctcttttttagttgctattcatataatagaaATTTtc aaaaaaaagttgTACGTGTATAATAAAACAAGgtaaagattgaaaggatttgagacga g" /listShort="aroC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2279111) /Source="Nicolas_upshifts" /id="U1806" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.943056943056943" /psig=1 /xcortree=2283 /SigmaFactorBS="taaggctcttttttagttgctattcatataatagaaATTTtc aaaaaaaagttgTACGTGTATAATAAAACAAGgtaaagattgaaaggatttgagacga g" /listShort="aroC" /GFF_Attribute="listLong" promotor_-35 complement(2279132..2279135) /Source="Nicolas_upshift_promotors" /id="U1806" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.943056943056943" /psig=1 /xcortree=2283 /SigmaFactorBS="taaggctcttttttagttgctattcatataatagaaATTTtc aaaaaaaagttgTACGTGTATAATAAAACAAGgtaaagattgaaaggatttgagacga g" /listShort="aroC" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 2279145 /Source="Nicolas_upshifts" /id="D1209" /incds=0 /nref=10 /ntot=52 /MaxReadThrough="2.02363" /MaxDrop="5.64228" /score="10.7892325" /energy="-8.5" /TU="NA" /idTUdmin="U1805" /TUdmin=704 /isTUend="FALSE" CDS complement(2279183..2280289) /gene="rsiX" /locus_tag="BSU_23090" /old_locus_tag="BSU23090" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:9139908, 9393439, 10712692, 14762009, 16306698" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9139908, 9393439, 10712692, 14762009, 16306698; Product type r: regulator" /codon_start=1 /transl_table=11 /product="negative regulator of sigma(X) activity" /protein_id="NP_390190.2" /db_xref="EnsemblGenomes-Gn:BSU23090" /db_xref="EnsemblGenomes-Tr:CAB14241" /db_xref="GOA:P35166" /db_xref="InterPro:IPR019606" /db_xref="SubtiList:BG10537" /db_xref="UniProtKB/Swiss-Prot:P35166" /translation="MMKSEWNEEQIKELLSQLPAVKDHRSPQDIYKRLTMAKRKNKPA VRWIGPACAAAIAVYIAFIISPHFFDQAQPQQKEASQENAVTKTETEDSPKAASSLDQ TSFVVPEKEQDNYITVAVADADTSAIIPVSIQKTNADQTIQDMLFESSELGILDHAIT IPTFIDEVEIKEKPKQKELSIRVHQPATAFSIKDDTLLKKLLKESLKWSPYEKVKFLS DQNETGVRIGSYGTFTEISIPKQSKRSYYLYQNKQGQDFLVPSNHSFDTVKEAIKEME SSSQEDTTPLIQAGAVQSVTKKQKHLYIRFSKESEVDDSIAGILMIEGLLLTAKEFGF TEVTFTETRTKKIGKYDISDAIPVPAAPNPISLN*" gene complement(2279183..2280289) /gene="rsiX" /locus_tag="BSU_23090" /old_locus_tag="BSU23090" downshifts complement(2279200) /Source="Nicolas_upshifts" /id="D1210" /incds=0 /nref=155 /ntot=242 /MaxReadThrough="3.84557" /MaxDrop="5.30684" /score="7.9467954" /energy="-6.7" /TU="U1809" /idTUdmin="U1806" /TUdmin="-881" /isTUend="FALSE" CDS complement(2280225..2280809) /gene="sigX" /locus_tag="BSU_23100" /old_locus_tag="BSU23100" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:9636707, 11222589, 12399481, 14762009, 19767430, 27965645" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9636707, 11222589, 12399481, 14762009, 19767430, 27965645; Product type r : regulator" /codon_start=1 /transl_table=11 /product="RNA polymerase ECF(extracytoplasmic function)-type sigma factor sigma(X)" /protein_id="NP_390191.2" /db_xref="EnsemblGenomes-Gn:BSU23100" /db_xref="EnsemblGenomes-Tr:CAB14242" /db_xref="GOA:P35165" /db_xref="InterPro:IPR000838" /db_xref="InterPro:IPR007627" /db_xref="InterPro:IPR013249" /db_xref="InterPro:IPR013324" /db_xref="InterPro:IPR013325" /db_xref="InterPro:IPR014284" /db_xref="InterPro:IPR036388" /db_xref="SubtiList:BG10536" /db_xref="UniProtKB/Swiss-Prot:P35165" /translation="MEETFQLLYDTYHQDLYQFLFYMVKDKNQTEDLLQEVYIRVLNS YHTFEGRSSEKTWLLSIARHVAIDWFRKQQTIRQRILGTFDWDTQDVRDQQLLPDELA VQHENVREIYAALDQCTIDQRAVIILRFIQGYSIQETAKALRFSESKVKTTQHRGLKV LRKHMELLREELMDDEVRMERRTDKGVVKSTSGS*" gene complement(2280225..2280809) /gene="sigX" /locus_tag="BSU_23100" /old_locus_tag="BSU23100" promotor_-35 2280603..2280608 /Source="Nicolas_upshift_promotors" /id="U1807" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.95004995004995" /psig="0.018981018981019" /xcortree=30 /SigmaFactorBS="aatgtaccgagtatacgctgtctgattgtttgctgtttacgg aaCCAGTCtatcgcaacatggcGTGCGatagacaaaagccatgttttttcactgcttc t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 2280619 /Source="Nicolas_upshifts" /id="U1807" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.95004995004995" /psig="0.018981018981019" /xcortree=30 /SigmaFactorBS="aatgtaccgagtatacgctgtctgattgtttgctgtttacgg aaCCAGTCtatcgcaacatggcGTGCGatagacaaaagccatgttttttcactgcttc t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 2280623..2280627 /Source="Nicolas_upshift_promotors" /id="U1807" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.95004995004995" /psig="0.018981018981019" /xcortree=30 /SigmaFactorBS="aatgtaccgagtatacgctgtctgattgtttgctgtttacgg aaCCAGTCtatcgcaacatggcGTGCGatagacaaaagccatgttttttcactgcttc t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 2280760..2280765 /Source="Nicolas_upshift_promotors" /id="U1808" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.956043956043956" /psig="0.956043956043956" /xcortree=1055 /SigmaFactorBS="ttctgtctggtttttatcctttaccatataaaataaaaattg gTACAAAtcttgatgatatgtaTCATATAATAATTGAAAGGtttcttccatttgaaac c" /listShort="S877" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 2280777 /Source="Nicolas_upshifts" /id="U1808" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.956043956043956" /psig="0.956043956043956" /xcortree=1055 /SigmaFactorBS="ttctgtctggtttttatcctttaccatataaaataaaaattg gTACAAAtcttgatgatatgtaTCATATAATAATTGAAAGGtttcttccatttgaaac c" /listShort="S877" /GFF_Attribute="listLong" promotor_-10 2280781..2280799 /Source="Nicolas_upshift_promotors" /id="U1808" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.956043956043956" /psig="0.956043956043956" /xcortree=1055 /SigmaFactorBS="ttctgtctggtttttatcctttaccatataaaataaaaattg gTACAAAtcttgatgatatgtaTCATATAATAATTGAAAGGtttcttccatttgaaac c" /listShort="S877" /GFF_Attribute="listLong" /label="promotor_-10" downshifts 2280817 /Source="Nicolas_upshifts" /id="D1211" /incds=0 /nref=8 /ntot=81 /MaxReadThrough="5.89234" /MaxDrop="4.38483" /score="6.57298987" /energy="-13.5" /TU="U1808" /idTUdmin="U1807" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(2280858..2280877) /Source="Nicolas_upshift_promotors" /id="U1809" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.565434565434565" /psig="0.998001998001998" /xcortree=2781 /SigmaFactorBS="aaaatttaaggatatgttaatataaattcCCTTCCAAattcc agttactCGTAATATAGTTGTAATGTAacttttcaagctattcatacgacaaaaaagt g" /listShort="sigX, rsiX, aroC" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 2280862..2280969 /Source="Nicolas_S_feature" /locus_tag="new_2415264_2415371" /HighExp="S4, S8, S6, S7, C30, S3, LoTm, B60, BT, S5" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigEF" /TUshortPSig="0.956" /TUlongSig="NA" /TUlongPSig="NA" /label="S877" upshifts complement(2280866) /Source="Nicolas_upshifts" /id="U1809" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.565434565434565" /psig="0.998001998001998" /xcortree=2781 /SigmaFactorBS="aaaatttaaggatatgttaatataaattcCCTTCCAAattcc agttactCGTAATATAGTTGTAATGTAacttttcaagctattcatacgacaaaaaagt g" /listShort="sigX, rsiX, aroC" /GFF_Attribute="listLong" promotor_-35 complement(2280890..2280897) /Source="Nicolas_upshift_promotors" /id="U1809" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.565434565434565" /psig="0.998001998001998" /xcortree=2781 /SigmaFactorBS="aaaatttaaggatatgttaatataaattcCCTTCCAAattcc agttactCGTAATATAGTTGTAATGTAacttttcaagctattcatacgacaaaaaagt g" /listShort="sigX, rsiX, aroC" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 2280925 /Source="Nicolas_upshifts" /id="D1212" /incds=0 /nref=12 /ntot=64 /MaxReadThrough="2.08559" /MaxDrop="4.36303" /score="6.57298987" /energy="-13.5" /TU="NA" /idTUdmin="U1808" /TUdmin="-2" /isTUend="TRUE" S_feature complement(2280954..2281012) /Source="Nicolas_S_feature" /locus_tag="new_2415356_2415414_c" /HighExp="Lbstat, BI, nit, S0, M40t90, Lbtran, M0t90, G135, Sw, ferm" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="NA" /TUshortPSig="NA" /TUlongSig="NA" /TUlongPSig="NA" /label="S878" downshifts complement(2280985) /Source="Nicolas_upshifts" /id="D1213" /incds=0 /nref=156 /ntot=252 /MaxReadThrough="2.62215" /MaxDrop="6.99198" /score="33.3049318" /energy="-13.5" /TU="NA" /idTUdmin="U1810" /TUdmin="-4" /isTUend="TRUE" CDS complement(2281013..2282782) /gene="resE" /locus_tag="BSU_23110" /old_locus_tag="BSU23110" /function="16.3: Control" /function="16.12: Sense" /experiment="publication(s) with functional evidences, PMID:11222591, 14996800, 16825793, 16885456, 17189364, 17322317, 17628154" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11222591, 14996800, 16825793, 16885456, 17189364, 17322317, 17628154; Product type rc: receptor" /codon_start=1 /transl_table=11 /product="two-component sensor histidine kinase (ResD / ResE)" /protein_id="NP_390192.1" /db_xref="EnsemblGenomes-Gn:BSU23110" /db_xref="EnsemblGenomes-Tr:CAB14243" /db_xref="GOA:P35164" /db_xref="InterPro:IPR000014" /db_xref="InterPro:IPR003594" /db_xref="InterPro:IPR003660" /db_xref="InterPro:IPR003661" /db_xref="InterPro:IPR004358" /db_xref="InterPro:IPR005467" /db_xref="InterPro:IPR013767" /db_xref="InterPro:IPR035965" /db_xref="InterPro:IPR036097" /db_xref="InterPro:IPR036890" /db_xref="PDB:4ZR7" /db_xref="SubtiList:BG10535" /db_xref="UniProtKB/Swiss-Prot:P35164" /translation="MKFWKSVVGKLWFTILSLVLIVLFILTVLLLEFIENYHVEEAEN DLTQLANKVAVILENHEDQALARSITWELADNLTSIAIIQDEKNHWYSPNDKNRLSSI TVEQIQHDKDLNKALKDHKKVSKRTGLSDTDTDNERLIVGVPYEKDGKKGMVFLSQSL LAVKDTTKHTTRYIFLAAGIAIVLTTFFAFFLSSRVTYPLRKMREGAQDLAKGKFDTK IPILTQDEIGELATAFNQMGRQLNFHINALNQEKEQLSNILSSMADGVITINIDGTIL VTNPPAERFLQAWYYEQNMNIKEGDNLPPEAKELFQNAVSTEKEQMIEMTLQGRSWVL LMSPLYAESHVRGAVAVLRDMTEERRLDKLREDFIANVSHELRTPISMLQGYSEAIVD DIASSEEDRKEIAQIIYDESLRMGRLVNDLLDLARMESGHTGLHYEKINVNEFLEKII RKFSGVAKEKNIALDHDISLTEEEFMFDEDKMEQVFTNLIDNALRHTSAGGSVSISVH SVKDGLKIDIKDSGSGIPEEDLPFIFERFYKADKARTRGRAGTGLGLAIVKNIVEAHN GSITVHSRIDKGTTFSFYIPTKR*" gene complement(2281013..2282782) /gene="resE" /locus_tag="BSU_23110" /old_locus_tag="BSU23110" downshifts complement(2281069) /Source="Nicolas_upshifts" /id="D1214" /incds=0 /nref=5 /ntot=13 /MaxReadThrough="7.56028" /MaxDrop="3.58685" /score="33.3049318" /energy="-13.5" /TU="U1810,U1811,U1812" /idTUdmin="U1810" /TUdmin="-88" /isTUend="FALSE" CDS complement(2282779..2283501) /gene="resD" /locus_tag="BSU_23120" /old_locus_tag="BSU23120" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:10972836, 15028686, 15375128, 16825793, 16885456, 17322317, 17628154" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10972836, 15028686, 15375128, 16825793, 16885456, 17322317, 17628154; Product type r: regulator" /codon_start=1 /transl_table=11 /product="two-component response regulator (ResD / ResE)" /protein_id="NP_390193.2" /db_xref="EnsemblGenomes-Gn:BSU23120" /db_xref="EnsemblGenomes-Tr:CAB14244" /db_xref="GOA:P35163" /db_xref="InterPro:IPR001789" /db_xref="InterPro:IPR001867" /db_xref="InterPro:IPR011006" /db_xref="InterPro:IPR036388" /db_xref="SubtiList:BG10534" /db_xref="UniProtKB/Swiss-Prot:P35163" /translation="MDQTNETKILVVDDEARIRRLLRMYLERENYAIDEAENGDEAIA KGLEANYDLILLDLMMPGTDGIEVCRQIREKKATPIIMLTAKGEEANRVQGFEAGTDD YIVKPFSPREVVLRVKALLRRASQTSYFNANTPTKNVLVFSHLSIDHDAHRVTADGTE VSLTPKEYELLYFLAKTPDKVYDREKLLKEVWQYEFFGDLRTVDTHVKRLREKLNKVS PEAAKKIVTVWGVGYKFEVGAE*" gene complement(2282779..2283501) /gene="resD" /locus_tag="BSU_23120" /old_locus_tag="BSU23120" S_feature complement(2283502..2283581) /Source="Nicolas_S_feature" /locus_tag="new_2417904_2417983_c" /HighExp="Lbstat, M0t90, ferm, M40t90, S2, S0, nit, M40t45, BI, Lbtran" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA, SigEF" /TUshortPSig="0.998, 0.998, 0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S879" CDS complement(2283582..2284757) /gene="resC" /locus_tag="BSU_23130" /old_locus_tag="BSU23130" /function="16.10: Respire" /experiment="publication(s) with functional evidences, PMID:10844653, 12682299, 15849754, 16850406, 19682263" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10844653, 12682299, 15849754, 16850406, 19682263; Product type f: factor" /codon_start=1 /transl_table=11 /product="factor required for cytochrome c synthesis" /protein_id="NP_390194.2" /db_xref="EnsemblGenomes-Gn:BSU23130" /db_xref="EnsemblGenomes-Tr:CAB14245" /db_xref="GOA:P35162" /db_xref="InterPro:IPR002541" /db_xref="InterPro:IPR017562" /db_xref="SubtiList:BG10533" /db_xref="UniProtKB/Swiss-Prot:P35162" /translation="MAELSGNFLYAAFLVYLIAVPIFGGAIRGNKDKKGRPNRWANIG ITLSIVGFFCHLGYFITRWAASGHAPVSNMFEFTTAFGMMLVLAFIILYFLYRLPSLG LFTLSIALLLIAYASMFPTDISPLIPSLQSNWLYIHVTTAALGQAILAISFVAGVIFL LKHVDQTKPSKKTFWLEAIMFILVTTVAFIAITSAFRLAGYEAEFNWVDKSKEKSVMV YEMPALVGPHQGELLTEGRMEPLVDLPALFSGRKVNTVIWSFGAGLVLYGALRLIIRK RISALLHPLVKNVNLDLVDEVGYRAVSIGFPIFTLGALIFAMIWAQLAWTRFWGWDPK EVWALITFLFYAAYLHLRLSRGWHGEKSAWLAVIGFAIIMFNLIFVNLVLAGLHSYA* " gene complement(2283582..2284757) /gene="resC" /locus_tag="BSU_23130" /old_locus_tag="BSU23130" CDS complement(2284777..2286405) /gene="resB" /locus_tag="BSU_23140" /old_locus_tag="BSU23140" /function="16.10: Respire" /experiment="publication(s) with functional evidences, PMID:9395519, 10844653, 12682299, 16825793, 19682263" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9395519, 10844653, 12682299, 16825793, 19682263; Product type f: factor" /codon_start=1 /transl_table=11 /product="factor required for cytochrome c synthesis" /protein_id="NP_390195.1" /db_xref="EnsemblGenomes-Gn:BSU23140" /db_xref="EnsemblGenomes-Tr:CAB14246" /db_xref="GOA:P35161" /db_xref="InterPro:IPR007816" /db_xref="SubtiList:BG10532" /db_xref="UniProtKB/Swiss-Prot:P35161" /translation="MKQVKCECGHINPVGTVLCESCGRALQETQPPLADMRYDGSARR SQTYNKTIIDKIWNFFSSVKVGIWLIVITLAASAFGTIFPQEAYLPPGAQADTYYKEQ YGTFGQLYYLLGFHHLYGSWWYLLLIASIGISLVICSLDRVIPLYRALKNQGVRRSPA FLRRQRLFSETVTVLNGESKEKIVTLLKKKHYRIREKEGSILAEKGRFSRWGPYVNHI GLIIFLIGAMLRFVPGMYVDETLWVREGETAAIPGTDGKYYLKNNQFSVETYNSKTEK KVFADAIDRVGDGRVAKNFQTDAVLYKREGKIVYGEKPKLEKVTEEDIRVNQPLRFDS FSVYQVDYKENQLDQMVFQLIDKKTKKSFGSLKINLLDPDSVYDLGNGYKVEIASYLP DFYFNQDGEPSTKTKIPNNPAFVFNIITPDKPKGEKSFVAIQETIEGSGNNKYKLKFD HVETKNITGLTVRKDLTLWVLAVGGAIFMIGVIQGMYWQHRRIWLHSQDGAVMVAGHT NKNWFGLKKDLAFILADSGLTEPVDQKELIKTQK*" gene complement(2284777..2286405) /gene="resB" /locus_tag="BSU_23140" /old_locus_tag="BSU23140" CDS complement(2286402..2286941) /gene="resA" /locus_tag="BSU_23150" /old_locus_tag="BSU23150" /function="16.10: Respire" /experiment="publication(s) with functional evidences, PMID:12637552, 12682299, 15667290, 16537372, 16825793, 16971393, 17189364, 18456809, 19682263, 22720735, 26735940" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12637552, 12682299, 15667290, 16537372, 16825793, 16971393, 17189364, 18456809, 19682263, 22720735, 26735940; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="extracytoplasmic thioredoxin involved in cytochrome c maturation (lipoprotein)" /protein_id="NP_390196.2" /db_xref="EnsemblGenomes-Gn:BSU23150" /db_xref="EnsemblGenomes-Tr:CAB14247" /db_xref="GOA:P35160" /db_xref="InterPro:IPR000866" /db_xref="InterPro:IPR013766" /db_xref="InterPro:IPR017937" /db_xref="InterPro:IPR023555" /db_xref="InterPro:IPR036249" /db_xref="PDB:1ST9" /db_xref="PDB:1SU9" /db_xref="PDB:2F9S" /db_xref="PDB:2H19" /db_xref="PDB:2H1A" /db_xref="PDB:2H1B" /db_xref="PDB:2H1D" /db_xref="PDB:2H1G" /db_xref="PDB:3C71" /db_xref="PDB:3C73" /db_xref="SubtiList:BG10531" /db_xref="UniProtKB/Swiss-Prot:P35160" /translation="MKKKRRLFIRTGILLVLICALGYTIYNAVFAGKESISEGSDAPN FVLEDTNGKRIELSDLKGKGVFLNFWGTWCEPCKKEFPYMANQYKHFKSQGVEIVAVN VGESKIAVHNFMKSYGVNFPVVLDTDRQVLDAYDVSPLPTTFLINPEGKVVKVVTGTM TESMIHDYMNLIKPGETSG*" gene complement(2286402..2286941) /gene="resA" /locus_tag="BSU_23150" /old_locus_tag="BSU23150" S_feature complement(2286942..2287035) /Source="Nicolas_S_feature" /locus_tag="new_2421344_2421437_c" /HighExp="LBGtran, LBGstat, G180, Oxctl, H2O2, G150, M0t90, G135, Paraq, LPhT" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA, SigEF" /TUshortPSig="0.998, 0.998, 0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S880" CDS complement(2287036..2287770) /gene="rluB" /locus_tag="BSU_23160" /old_locus_tag="BSU23160" /EC_number="4.2.1.70" /function="16.13: Shape" /function="16.8: Protect" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:9888802, 24214967" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9888802, 24214967; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="23S rRNA pseudouridine 2633 (=2605 standard) pseudouridine synthase" /protein_id="NP_390197.2" /db_xref="EnsemblGenomes-Gn:BSU23160" /db_xref="EnsemblGenomes-Tr:CAB14248" /db_xref="GOA:P35159" /db_xref="InterPro:IPR000748" /db_xref="InterPro:IPR002942" /db_xref="InterPro:IPR006145" /db_xref="InterPro:IPR018496" /db_xref="InterPro:IPR020103" /db_xref="InterPro:IPR036986" /db_xref="SubtiList:BG10530" /db_xref="UniProtKB/Swiss-Prot:P35159" /translation="MERLQKVIAHAGVASRRKAEELIKEGKVKVNGKVVTELGVKVTG SDQIEVNGLKVEREEPVYFLLYKPRGVISAAQDDKGRKVVTDFFKNIPQRIYPIGRLD YDTSGLLLLTNDGEFANKLMHPKYEIDKTYVAKVKGIPPKELLRKLERGIRLEEGKTA PAKAKLLSLDKKKQTSIIQLTIHEGRNRQVRRMFEAIGHEVIKLKREEYAFLNLRGLH TGDARELTPHEVKRLRALADHGKNAF*" gene complement(2287036..2287770) /gene="rluB" /locus_tag="BSU_23160" /old_locus_tag="BSU23160" promotor_-10 complement(2287779..2287798) /Source="Nicolas_upshift_promotors" /id="U1810" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.616383616383616" /psig="0.998001998001998" /xcortree=2676 /SigmaFactorBS="aaaacggcgttttttttagatttggcataggaatttgaaaaa gctTGTTTgttaaggttgaaaaAAGTAAGATAATACTTGAGGtgaaagacatggaaag a" /listShort="rluB, S880, resA, resB, resC, S879, resD, resE" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2287802) /Source="Nicolas_upshifts" /id="U1810" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.616383616383616" /psig="0.998001998001998" /xcortree=2676 /SigmaFactorBS="aaaacggcgttttttttagatttggcataggaatttgaaaaa gctTGTTTgttaaggttgaaaaAAGTAAGATAATACTTGAGGtgaaagacatggaaag a" /listShort="rluB, S880, resA, resB, resC, S879, resD, resE" /GFF_Attribute="listLong" promotor_-35 complement(2287813..2287817) /Source="Nicolas_upshift_promotors" /id="U1810" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.616383616383616" /psig="0.998001998001998" /xcortree=2676 /SigmaFactorBS="aaaacggcgttttttttagatttggcataggaatttgaaaaa gctTGTTTgttaaggttgaaaaAAGTAAGATAATACTTGAGGtgaaagacatggaaag a" /listShort="rluB, S880, resA, resB, resC, S879, resD, resE" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2287862..2288398) /gene="spmB" /locus_tag="BSU_23170" /old_locus_tag="BSU23170" /function="16.13: Shape" /function="16.5: Explore" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:7642500, 15849754, 16850406, 19189487" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7642500, 15849754, 16850406, 19189487; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="spore maturation protein" /protein_id="NP_390198.2" /db_xref="EnsemblGenomes-Gn:BSU23170" /db_xref="EnsemblGenomes-Tr:CAB14249" /db_xref="GOA:P35158" /db_xref="InterPro:IPR011642" /db_xref="SubtiList:BG10529" /db_xref="UniProtKB/Swiss-Prot:P35158" /translation="MEIINWLSLAMIPIIIAGILLYGTIKKVPTYESFVEGGKEGIEI AFSIIPYLVGMLVAITVFRSSGALDFIMDLLKPAFSAIGIPAEVVPLALIRPISGTAA LGMTTDLIAVYGPDSFIGRLASVMQGSTDTTLYVLTVYFGAVGIKKMGDALKVGLLAD LIGVVASIIIVTLLFGSA*" gene complement(2287862..2288398) /gene="spmB" /locus_tag="BSU_23170" /old_locus_tag="BSU23170" promotor_-10 complement(2287867..2287886) /Source="Nicolas_upshift_promotors" /id="U1811" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.816183816183816" /psig="0.998001998001998" /xcortree=2645 /SigmaFactorBS="acttcttgcagatttaatcggcgTAGTTGCAtctatcatcat cgtTACGTTATTATTTGGGAGCGcctgaaaacggcgttttttttagatttggcatagg a" /listShort="rluB, S880, resA, resB, resC, S879, resD, resE" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2287871) /Source="Nicolas_upshifts" /id="U1811" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.816183816183816" /psig="0.998001998001998" /xcortree=2645 /SigmaFactorBS="acttcttgcagatttaatcggcgTAGTTGCAtctatcatcat cgtTACGTTATTATTTGGGAGCGcctgaaaacggcgttttttttagatttggcatagg a" /listShort="rluB, S880, resA, resB, resC, S879, resD, resE" /GFF_Attribute="listLong" promotor_-35 complement(2287901..2287908) /Source="Nicolas_upshift_promotors" /id="U1811" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.816183816183816" /psig="0.998001998001998" /xcortree=2645 /SigmaFactorBS="acttcttgcagatttaatcggcgTAGTTGCAtctatcatcat cgtTACGTTATTATTTGGGAGCGcctgaaaacggcgttttttttagatttggcatagg a" /listShort="rluB, S880, resA, resB, resC, S879, resD, resE" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2288403..2288993) /gene="spmA" /locus_tag="BSU_23180" /old_locus_tag="BSU23180" /function="16.5: Explore" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:7642500, 15849754, 16850406, 19189487" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7642500, 15849754, 16850406, 19189487; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="spore maturation protein" /protein_id="NP_390199.1" /db_xref="EnsemblGenomes-Gn:BSU23180" /db_xref="EnsemblGenomes-Tr:CAB14250" /db_xref="GOA:P35157" /db_xref="InterPro:IPR011642" /db_xref="SubtiList:BG10528" /db_xref="UniProtKB/Swiss-Prot:P35157" /translation="MVNIIWVSLTVIGLVFAMCNGTLQDVNEAVFKGAKEAITISFGL MSVLVFWLGLMKIAEQSGLLDIFSRMCRPFISKLFPDIPPDHPAMGYILSNLMANFFG LGNAATPLGIKAMEQMKKLNGNRSEASRSMITFLAVNTSCITLIPTTVIAVRMAYSSK TPTDIVGPSILATLISGIGAIIIDRYFYYRRKKKGR*" gene complement(2288403..2288993) /gene="spmA" /locus_tag="BSU_23180" /old_locus_tag="BSU23180" CDS complement(2288981..2290129) /gene="dacB" /locus_tag="BSU_23190" /old_locus_tag="BSU23190" /EC_number="3.4.16.4" /function="16.13: Shape" /function="16.5: Explore" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:7642500, 8892816, 9864321, 10498740, 18266856, 19542328" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7642500, 8892816, 9864321, 10498740, 18266856, 19542328; Product type cp : cell process" /codon_start=1 /transl_table=11 /product="D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5*) (required for spore cortex)" /protein_id="NP_390200.1" /db_xref="EnsemblGenomes-Gn:BSU23190" /db_xref="EnsemblGenomes-Tr:CAB14251" /db_xref="GOA:P35150" /db_xref="InterPro:IPR001967" /db_xref="InterPro:IPR012338" /db_xref="InterPro:IPR012907" /db_xref="InterPro:IPR018044" /db_xref="PDB:3MFD" /db_xref="SubtiList:BG10527" /db_xref="UniProtKB/Swiss-Prot:P35150" /translation="MRIFKKAVFVIMISFLIATVNVNTAHAAIDVSAKSAIIIDGASG RVLYAKDEHQKRRIASITKIMTAVLAIESGKMDQTVTVSANAVRTEGSAIYLTEGQKV KLKDLVYGLMLRSGNDAAVAIAEHVGGSLDGFVYMMNQKAEQLGMKNTRFQNPHGLDD HENHYSTAYDMAILTKYAMKLKDYQKISGTKIYKAETMESVWKNKNKLLTMLYPYSTG GKTGYTKLAKRTLVSTASKDGIDLIAVTINDPNDWDDHMKMFNYVFEHYQTYLIAKKG DIPKLKGTFYESKAFIKRDITYLLTEEEKENVKINTTLLKPKKAWEKDASKIPDIVGH MEIMFNDATIAKVPIYYENERHQKPKKQFFETFKSIFLNAAGGAKWSI*" gene complement(2288981..2290129) /gene="dacB" /locus_tag="BSU_23190" /old_locus_tag="BSU23190" promotor_-10 complement(2290151..2290169) /Source="Nicolas_upshift_promotors" /id="U1812" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=990 /SigmaFactorBS="tatgtttgcttccagaaatataattgttaTTCATAactgatg gacatgcGCATAAACTTGTACAAACCaccacaaggacgtgagcaaacatgcgcatttt c" /listShort="dacB, spmA, spmB, rluB, S880, resA, resB, resC, S879, resD, resE" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2290158) /Source="Nicolas_upshifts" /id="U1812" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=990 /SigmaFactorBS="tatgtttgcttccagaaatataattgttaTTCATAactgatg gacatgcGCATAAACTTGTACAAACCaccacaaggacgtgagcaaacatgcgcatttt c" /listShort="dacB, spmA, spmB, rluB, S880, resA, resB, resC, S879, resD, resE" /GFF_Attribute="listLong" promotor_-35 complement(2290184..2290189) /Source="Nicolas_upshift_promotors" /id="U1812" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=990 /SigmaFactorBS="tatgtttgcttccagaaatataattgttaTTCATAactgatg gacatgcGCATAAACTTGTACAAACCaccacaaggacgtgagcaaacatgcgcatttt c" /listShort="dacB, spmA, spmB, rluB, S880, resA, resB, resC, S879, resD, resE" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2290252..2290791) /gene="ypuI" /locus_tag="BSU_23200" /old_locus_tag="BSU23200" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 12065423" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_390201.1" /db_xref="EnsemblGenomes-Gn:BSU23200" /db_xref="EnsemblGenomes-Tr:CAB14252" /db_xref="InterPro:IPR025013" /db_xref="SubtiList:BG10526" /db_xref="UniProtKB/Swiss-Prot:P35156" /translation="MKEAKCERQIHEGKIPNEMGHSIVRAQTQKTGEFLSMVVNTVND YLNQTTLESLQAELPIEKGYCCDVLSTLRRMAVFCEGGAEACRRLLMQEPFQEARAEK TLYNVYHQCIEEFFMPKKDTWCENSRASYTGVSAIEFYHAVPASLEQLLLPLSAAFLK MREELAHYEASGSSMAPIR*" gene complement(2290252..2290791) /gene="ypuI" /locus_tag="BSU_23200" /old_locus_tag="BSU23200" downshifts complement(2290265) /Source="Nicolas_upshifts" /id="D1215" /incds=0 /nref=219 /ntot=260 /MaxReadThrough="1.63638" /MaxDrop="8.00748" /score="36.7302977" /energy="-12.2" /TU="NA" /idTUdmin="U1813" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(2290800..2290817) /Source="Nicolas_upshift_promotors" /id="U1813" /multdbtbs="-" /comp="M3" /sig="Sig-" /pcomp="0.436563436563437" /psig="0.436563436563437" /xcortree=810 /SigmaFactorBS="tttaaccaaaccttcgaagatataaaatagaagtttaaTGAA TCgcgctttttcatcaTCATAAGATATAAGGAAGaagctatcatgaaagaagcaaaat g" /listShort="ypuI" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2290815) /Source="Nicolas_upshifts" /id="U1813" /multdbtbs="-" /comp="M3" /sig="Sig-" /pcomp="0.436563436563437" /psig="0.436563436563437" /xcortree=810 /SigmaFactorBS="tttaaccaaaccttcgaagatataaaatagaagtttaaTGAA TCgcgctttttcatcaTCATAAGATATAAGGAAGaagctatcatgaaagaagcaaaat g" /listShort="ypuI" /GFF_Attribute="listLong" promotor_-35 complement(2290832..2290837) /Source="Nicolas_upshift_promotors" /id="U1813" /multdbtbs="-" /comp="M3" /sig="Sig-" /pcomp="0.436563436563437" /psig="0.436563436563437" /xcortree=810 /SigmaFactorBS="tttaaccaaaccttcgaagatataaaatagaagtttaaTGAA TCgcgctttttcatcaTCATAAGATATAAGGAAGaagctatcatgaaagaagcaaaat g" /listShort="ypuI" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2290846..2291439) /gene="spcB" /locus_tag="BSU_23210" /old_locus_tag="BSU23210" /function="16.6: Maintain" /function="16.9: Replicate" /experiment="publication(s) with functional evidences, PMID:12065423, 12100548, 12682299, 12897137, 16272394, 23541893, 24440393, 25951515, 26904953, 27435445, 28286005" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12065423, 12100548, 12682299, 12897137, 16272394, 23541893, 24440393, 25951515, 26904953, 27435445, 28286005; Product type f : factor" /codon_start=1 /transl_table=11 /product="chromosome condensation and segregation factor" /protein_id="NP_390202.1" /db_xref="EnsemblGenomes-Gn:BSU23210" /db_xref="EnsemblGenomes-Tr:CAB14253" /db_xref="GOA:P35155" /db_xref="InterPro:IPR005234" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG10525" /db_xref="UniProtKB/Swiss-Prot:P35155" /translation="MGLDIVNWKAIVEALLYAAGDEGLTKKQLLTVLEIEEPELNTIM ADVADEYRGDTRGIELIEYADTYMLSTKKDFAPYLKKLIEVPSKGLSQASLEVLAIVS YKQPITRAEIEEIRGVKSERILHSLVAKALLCEVGRADGPGRAILYGTTPTFLEQFGL KTLDELPPLPENAEEDVLQEEADLFFENFNQTFEDIK*" gene complement(2290846..2291439) /gene="spcB" /locus_tag="BSU_23210" /old_locus_tag="BSU23210" CDS complement(2291429..2292184) /gene="scpA" /locus_tag="BSU_23220" /old_locus_tag="BSU23220" /function="16.13: Shape" /function="16.9: Replicate" /experiment="publication(s) with functional evidences, PMID:12065423, 12100548, 12682299, 12897137, 16272394, 23541893, 24440393, 25951515, 26904953, 28286005" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12065423, 12100548, 12682299, 12897137, 16272394, 23541893, 24440393, 25951515, 26904953, 28286005; Product type f: factor" /codon_start=1 /transl_table=11 /product="chromosome condensation and partitioning factor" /protein_id="NP_390203.1" /db_xref="EnsemblGenomes-Gn:BSU23220" /db_xref="EnsemblGenomes-Tr:CAB14254" /db_xref="GOA:P35154" /db_xref="InterPro:IPR003768" /db_xref="PDB:3ZGX" /db_xref="PDB:5H66" /db_xref="PDB:5H67" /db_xref="PDB:5XG3" /db_xref="SubtiList:BG10524" /db_xref="UniProtKB/Swiss-Prot:P35154" /translation="MEEYQVKIDTFEGPLDLLLHLINRLEIDIYDIPVAKITEQYLLY VHTMRVLELDIASEYLVMAATLLSIKSRMLLPKQEEELFEDELLEEEDPREELIEKLI EYRKYKDAAKDLKEREEERQKSFTKPPSDLSEYAKEVKQSEQKLSVTVYDMIGAFQKV LKRKKINRPMETTITRQDIPIEARMNEIVHSLKSRGTRINFMDLFPYEQKEHLVVTFL AVLELMKNQLVLIEQEHNFSDIYITGSESIHGA*" gene complement(2291429..2292184) /gene="scpA" /locus_tag="BSU_23220" /old_locus_tag="BSU23220" promotor_-35 2292028..2292037 /Source="Nicolas_upshift_promotors" /id="U1814" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1387 /SigmaFactorBS="cataaccaaatactcgctggcaatgtcgaGCTCAAGCACgcg catcgtatgTACATATAATAAATATTGTTcagtgatcttcgccacaggtatatcatat a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2292050..2292069 /Source="Nicolas_upshift_promotors" /id="U1814" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1387 /SigmaFactorBS="cataaccaaatactcgctggcaatgtcgaGCTCAAGCACgcg catcgtatgTACATATAATAAATATTGTTcagtgatcttcgccacaggtatatcatat a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2292059 /Source="Nicolas_upshifts" /id="U1814" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1387 /SigmaFactorBS="cataaccaaatactcgctggcaatgtcgaGCTCAAGCACgcg catcgtatgTACATATAATAAATATTGTTcagtgatcttcgccacaggtatatcatat a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 complement(2292230..2292249) /Source="Nicolas_upshift_promotors" /id="U1815" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.862137862137862" /psig=1 /xcortree=2560 /SigmaFactorBS="ctgtacaaactccttcaaaacaggatatgaaatagTATTGGA CgagagctttttggTGGCTTATACTATAGGGTAGccagtttttccggcaatgagagtg a" /listShort="scpA, spcB, ypuI" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2292245) /Source="Nicolas_upshifts" /id="U1815" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.862137862137862" /psig=1 /xcortree=2560 /SigmaFactorBS="ctgtacaaactccttcaaaacaggatatgaaatagTATTGGA CgagagctttttggTGGCTTATACTATAGGGTAGccagtttttccggcaatgagagtg a" /listShort="scpA, spcB, ypuI" /GFF_Attribute="listLong" promotor_-35 complement(2292263..2292270) /Source="Nicolas_upshift_promotors" /id="U1815" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.862137862137862" /psig=1 /xcortree=2560 /SigmaFactorBS="ctgtacaaactccttcaaaacaggatatgaaatagTATTGGA CgagagctttttggTGGCTTATACTATAGGGTAGccagtttttccggcaatgagagtg a" /listShort="scpA, spcB, ypuI" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 2292410..2292417 /Source="Nicolas_upshift_promotors" /id="U1816" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.984015984015984" /psig=1 /xcortree=2166 /SigmaFactorBS="tttcctttctaagaagcactagaggccgggcgttcttTTTTC CTTttatcccttcTATGGTACACTAAAAGCACAttaaaggaggaagcaccttgtatcc g" /listShort="ypuF" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2292428..2292447 /Source="Nicolas_upshift_promotors" /id="U1816" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.984015984015984" /psig=1 /xcortree=2166 /SigmaFactorBS="tttcctttctaagaagcactagaggccgggcgttcttTTTTC CTTttatcccttcTATGGTACACTAAAAGCACAttaaaggaggaagcaccttgtatcc g" /listShort="ypuF" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2292433 /Source="Nicolas_upshifts" /id="U1816" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.984015984015984" /psig=1 /xcortree=2166 /SigmaFactorBS="tttcctttctaagaagcactagaggccgggcgttcttTTTTC CTTttatcccttcTATGGTACACTAAAAGCACAttaaaggaggaagcaccttgtatcc g" /listShort="ypuF" /GFF_Attribute="listLong" CDS 2292465..2292989 /gene="ypuF" /locus_tag="BSU_23230" /old_locus_tag="BSU23230" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_390204.1" /db_xref="EnsemblGenomes-Gn:BSU23230" /db_xref="EnsemblGenomes-Tr:CAB14255" /db_xref="InterPro:IPR005500" /db_xref="InterPro:IPR023203" /db_xref="SubtiList:BG10523" /db_xref="UniProtKB/Swiss-Prot:P17617" /translation="MYPKAYIDYLVEFHATRDYFECHEILEEYWKEDPPKKRKRYWVG FIQLAVALYHHRRQNTAGAKRLMANSIRILQAEHRAVEDLGLDHGRLLELMQSVYEQI ETVSAYKSIILPIKDEKLEEACRIECRKKKYTWGQPSALSNIFLIDKHRLRDRTDVIR EREKEIERRKKSRD*" gene 2292465..2292989 /gene="ypuF" /locus_tag="BSU_23230" /old_locus_tag="BSU23230" CDS complement(2293003..2293377) /gene="ypzK" /locus_tag="BSU_23240" /old_locus_tag="BSU23240" /function="16.8: Protect" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15466513, 25349719; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative riboflavin synthesis-related N-acetyltransferase" /protein_id="NP_390205.1" /db_xref="EnsemblGenomes-Gn:BSU23240" /db_xref="EnsemblGenomes-Tr:CAB14256" /db_xref="GOA:P17622" /db_xref="InterPro:IPR000182" /db_xref="InterPro:IPR016181" /db_xref="SubtiList:BG10522" /db_xref="UniProtKB/Swiss-Prot:P17622" /translation="MLIRYKKSFEKIAMGLLSFMPNEKDLKQLQQTIKDYETDTDRQL FLWKEDEDIVGAIGVEKKDSEVEIRHISVNPSHRHQGIGKQMMDALKHLFKTQVLVPN ELTQSFFERCQGQQDQDISYNN*" gene complement(2293003..2293377) /gene="ypzK" /locus_tag="BSU_23240" /old_locus_tag="BSU23240" downshifts complement(2293019) /Source="Nicolas_upshifts" /id="D1216" /incds=0 /nref=264 /ntot=275 /MaxReadThrough="1.34496" /MaxDrop="8.09525" /score="39.5464967" /energy="-14.3" /TU="NA" /idTUdmin="U1817" /TUdmin="-4" /isTUend="TRUE" promotor_-10 complement(2293439..2293458) /Source="Nicolas_upshift_promotors" /id="U1817" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.601398601398601" /psig="0.993006993006993" /xcortree=420 /SigmaFactorBS="tttaaaccgctcatttgaataatttgctgaaaacAGTTTAAA aatatggcgaaAATGATATAATGTGAGAAAAcggatcacctattcgtatccgttaata g" /listShort="ypzK" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2293451) /Source="Nicolas_upshifts" /id="U1817" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.601398601398601" /psig="0.993006993006993" /xcortree=420 /SigmaFactorBS="tttaaaccgctcatttgaataatttgctgaaaacAGTTTAAA aatatggcgaaAATGATATAATGTGAGAAAAcggatcacctattcgtatccgttaata g" /listShort="ypzK" /GFF_Attribute="listLong" promotor_-35 complement(2293470..2293477) /Source="Nicolas_upshift_promotors" /id="U1817" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.601398601398601" /psig="0.993006993006993" /xcortree=420 /SigmaFactorBS="tttaaaccgctcatttgaataatttgctgaaaacAGTTTAAA aatatggcgaaAATGATATAATGTGAGAAAAcggatcacctattcgtatccgttaata g" /listShort="ypzK" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2293490..2293954) /gene="ribH" /locus_tag="BSU_23250" /old_locus_tag="BSU23250" /EC_number="2.5.1.78" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:3100522, 7473709, 10881048, 12456892, 24442413" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 3100522, 7473709, 10881048, 12456892, 24442413; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="6,7-dimethyl-8-ribityllumazine synthase, beta subunit" /protein_id="NP_390206.1" /db_xref="EnsemblGenomes-Gn:BSU23250" /db_xref="EnsemblGenomes-Tr:CAB14257" /db_xref="GOA:P11998" /db_xref="InterPro:IPR002180" /db_xref="InterPro:IPR034964" /db_xref="InterPro:IPR036467" /db_xref="PDB:1RVV" /db_xref="PDB:1ZIS" /db_xref="SubtiList:BG10521" /db_xref="UniProtKB/Swiss-Prot:P11998" /translation="MNIIQGNLVGTGLKIGIVVGRFNDFITSKLLSGAEDALLRHGVD TNDIDVAWVPGAFEIPFAAKKMAETKKYDAIITLGTVIRGATTHYDYVCNEAAKGIAQ AANTTGVPVIFGIVTTENIEQAIERAGTKAGNKGVDCAVSAIEMANLNRSFE*" gene complement(2293490..2293954) /gene="ribH" /locus_tag="BSU_23250" /old_locus_tag="BSU23250" promotor_-35 2293825..2293829 /Source="Nicolas_upshift_promotors" /id="U1818" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.974025974025974" /psig="0.000999000999001" /xcortree=35 /SigmaFactorBS="atgcgcctggaacccaagccacatcaatgtcatttgtgtCTA CGccatgtctgagcaGCGCAtcttctgctccgctcagcagcttgctcgtaataaaatc a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2293843..2293847 /Source="Nicolas_upshift_promotors" /id="U1818" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.974025974025974" /psig="0.000999000999001" /xcortree=35 /SigmaFactorBS="atgcgcctggaacccaagccacatcaatgtcatttgtgtCTA CGccatgtctgagcaGCGCAtcttctgctccgctcagcagcttgctcgtaataaaatc a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2293846 /Source="Nicolas_upshifts" /id="U1818" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.974025974025974" /psig="0.000999000999001" /xcortree=35 /SigmaFactorBS="atgcgcctggaacccaagccacatcaatgtcatttgtgtCTA CGccatgtctgagcaGCGCAtcttctgctccgctcagcagcttgctcgtaataaaatc a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" CDS complement(2293987..2295183) /gene="ribBA" /locus_tag="BSU_23260" /old_locus_tag="BSU23260" /EC_number="3.5.4.25" /EC_number="4.1.99.12" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:9297088, 9515916, 12456892, 19583770, 24442413" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9297088, 9515916, 12456892, 19583770, 24442413; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="fused 3,4-dihydroxy-2-butanone 4-phosphate synthase and GTP cyclohydrolase II" /protein_id="NP_390207.1" /db_xref="EnsemblGenomes-Gn:BSU23260" /db_xref="EnsemblGenomes-Tr:CAB14258" /db_xref="GOA:P17620" /db_xref="InterPro:IPR000422" /db_xref="InterPro:IPR000926" /db_xref="InterPro:IPR016299" /db_xref="InterPro:IPR017945" /db_xref="InterPro:IPR032677" /db_xref="InterPro:IPR036144" /db_xref="SubtiList:BG10520" /db_xref="UniProtKB/Swiss-Prot:P17620" /translation="MFHPIEEALDALKKGEVIIVVDDEDRENEGDFVALAEHATPEVI NFMATHGRGLICTPLSEEIADRLDLHPMVEHNTDSHHTAFTVSIDHRETKTGISAQER SFTVQALLDSKSVPSDFQRPGHIFPLIAKKGGVLKRAGHTEAAVDLAEACGSPGAGVI CEIMNEDGTMARVPELIEIAKKHQLKMITIKDLIQYRYNLTTLVEREVDITLPTDFGT FKVYGYTNEVDGKEHVAFVMGDVPFGEEPVLVRVHSECLTGDVFGSHRCDCGPQLHAA LNQIAAEGRGVLLYLRQEGRGIGLINKLKAYKLQEQGYDTVEANEALGFLPDLRNYGI GAQILRDLGVRNMKLLTNNPRKIAGLEGYGLSISERVPLQMEAKEHNKKYLQTKMNKL GHLLHF*" gene complement(2293987..2295183) /gene="ribBA" /locus_tag="BSU_23260" /old_locus_tag="BSU23260" CDS complement(2295198..2295845) /gene="ribE" /locus_tag="BSU_23270" /old_locus_tag="BSU23270" /EC_number="2.5.1.9" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:2106516, 12456892" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 2106516, 12456892; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="riboflavin synthase (alpha subunit)" /protein_id="NP_390208.1" /db_xref="EnsemblGenomes-Gn:BSU23270" /db_xref="EnsemblGenomes-Tr:CAB14259" /db_xref="GOA:P16440" /db_xref="InterPro:IPR001783" /db_xref="InterPro:IPR017938" /db_xref="InterPro:IPR023366" /db_xref="InterPro:IPR026017" /db_xref="SubtiList:BG10519" /db_xref="UniProtKB/Swiss-Prot:P16440" /translation="MFTGIIEETGTIESMKKAGHAMALTIKCSKILEDVHLGDSIAVN GICLTVTDFTKNQFTVDVMPETVKATSLNDLTKGSKVNLERAMAANGRFGGHFVSGHV DGTAEITRIEEKSNAVYYDLKMDPSLTKTLVLKGSITVDGVSLTIFGLTEDTVTISLI PHTISETIFSEKTIGSKVNIECDMIGKYMYRFLHKANENKTQQTITKAFLSENGF*" gene complement(2295198..2295845) /gene="ribE" /locus_tag="BSU_23270" /old_locus_tag="BSU23270" CDS complement(2295856..2296941) /gene="ribD" /locus_tag="BSU_23280" /old_locus_tag="BSU23280" /EC_number="1.1.1.193" /EC_number="3.5.4.26" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:9068650, 12456892, 17765262, 18986985, 23385458" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9068650, 12456892, 17765262, 18986985, 23385458; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="fused diaminohydroxyphosphoribosylaminopyrimidine deaminase; 5-amino-6-(5-phosphoribosylamino) uracil reductase" /protein_id="NP_390209.1" /db_xref="EnsemblGenomes-Gn:BSU23280" /db_xref="EnsemblGenomes-Tr:CAB14260" /db_xref="GOA:P17618" /db_xref="InterPro:IPR002125" /db_xref="InterPro:IPR002734" /db_xref="InterPro:IPR004794" /db_xref="InterPro:IPR011549" /db_xref="InterPro:IPR016192" /db_xref="InterPro:IPR016193" /db_xref="InterPro:IPR024072" /db_xref="PDB:2B3Z" /db_xref="PDB:2D5N" /db_xref="PDB:3EX8" /db_xref="PDB:4G3M" /db_xref="SubtiList:BG10518" /db_xref="UniProtKB/Swiss-Prot:P17618" /translation="MEEYYMKLALDLAKQGEGQTESNPLVGAVVVKDGQIVGMGAHLK YGEAHAEVHAIHMAGAHAEGADIYVTLEPCSHYGKTPPCAELIINSGIKRVFVAMRDP NPLVAGRGISMMKEAGIEVREGILADQAERLNEKFLHFMRTGLPYVTLKAAASLDGKI ATSTGDSKWITSEAARQDAQQYRKTHQSILVGVGTVKADNPSLTCRLPNVTKQPVRVI LDTVLSIPEDAKVICDQIAPTWIFTTARADEEKKKRLSAFGVNIFTLETERIQIPDVL KILAEEGIMSVYVEGGSAVHGSFVKEGCFQEIIFYFAPKLIGGTHAPSLISGEGFQSM KDVPLLQFTDITQIGRDIKLTAKPTKE*" gene complement(2295856..2296941) /gene="ribD" /locus_tag="BSU_23280" /old_locus_tag="BSU23280" S_feature complement(2296942..2297070) /Source="Nicolas_S_feature" /locus_tag="new_2431344_2431472_c" /HighExp="T0.30H, B60, T1.30H, T2.0H, MG-0.2, T1.0H, S1, T0.0H, LPhT, T-0.40H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.996" /TUlongSig="NA" /TUlongPSig="NA" /label="S881" misc_RNA complement(2297071..2297215) /gene="fswA" /locus_tag="BSU_misc_RNA_36" /product="flavin riboswitch" /experiment="publication(s) with functional evidences, PMID:12456892, 15808508, 17693491, 17997835" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12456892, 15808508, 17693491, 17997835; Product type n: RNA" gene complement(2297071..2297215) /gene="fswA" /locus_tag="BSU_misc_RNA_36" promotor_-10 complement(2297232..2297251) /Source="Nicolas_upshift_promotors" /id="U1819" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.437562437562438" /psig="0.996003996003996" /xcortree=606 /SigmaFactorBS="tttgtttttctcaaattgtaagtttatttCATTGCGTacttt aaaaaggatCGCTATAATAACCAATAAGGacaaatgaataaagattgtatccttcggg g" /listShort="NA, S881, ribD, ribE, ribAB, ribH, ypzK" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2297242) /Source="Nicolas_upshifts" /id="U1819" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.437562437562438" /psig="0.996003996003996" /xcortree=606 /SigmaFactorBS="tttgtttttctcaaattgtaagtttatttCATTGCGTacttt aaaaaggatCGCTATAATAACCAATAAGGacaaatgaataaagattgtatccttcggg g" /listShort="NA, S881, ribD, ribE, ribAB, ribH, ypzK" /GFF_Attribute="listLong" promotor_-35 complement(2297266..2297273) /Source="Nicolas_upshift_promotors" /id="U1819" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.437562437562438" /psig="0.996003996003996" /xcortree=606 /SigmaFactorBS="tttgtttttctcaaattgtaagtttatttCATTGCGTacttt aaaaaggatCGCTATAATAACCAATAAGGacaaatgaataaagattgtatccttcggg g" /listShort="NA, S881, ribD, ribE, ribAB, ribH, ypzK" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2297335..2297679) /gene="ypuD" /locus_tag="BSU_23300" /old_locus_tag="BSU23300" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_390211.1" /db_xref="EnsemblGenomes-Gn:BSU23300" /db_xref="EnsemblGenomes-Tr:CAB14262" /db_xref="SubtiList:BG10516" /db_xref="UniProtKB/Swiss-Prot:P17616" /translation="MGRIKTKITILLVLLLLLAGGYMYINDIELKDVPTAIGQTLSSE EEEYTIQEYKVTKIDGSEYHGVAENGTKIIFNGKKLNQDLSDIKEGDKIKAYFSKSKR IDGLIKVAKVND*" gene complement(2297335..2297679) /gene="ypuD" /locus_tag="BSU_23300" /old_locus_tag="BSU23300" downshifts complement(2297350) /Source="Nicolas_upshifts" /id="D1217" /incds=0 /nref=78 /ntot=221 /MaxReadThrough="1.58771" /MaxDrop="5.14851" /score="20.5522057" /energy="-14.7" /TU="NA" /idTUdmin="U1820" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(2297711..2297729) /Source="Nicolas_upshift_promotors" /id="U1820" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=749 /SigmaFactorBS="tgcatcgttatattaataatttacgagaatttacGGTTTTTt attcatgaaaaaaAGGAATAACTCATATGAATgaatagattcatattggctggaggtt t" /listShort="ypuD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2297724) /Source="Nicolas_upshifts" /id="U1820" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=749 /SigmaFactorBS="tgcatcgttatattaataatttacgagaatttacGGTTTTTt attcatgaaaaaaAGGAATAACTCATATGAATgaatagattcatattggctggaggtt t" /listShort="ypuD" /GFF_Attribute="listLong" promotor_-35 2297738..2297743 /Source="Nicolas_upshift_promotors" /id="U1821" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=1077 /SigmaFactorBS="tatgaatctattcattcatatgagttattcctttttttcaTG AATAaaaaaccgtaaattcTCGTAAATTATTAATATAAcgatgcataacgggaatatg t" /listShort="S882" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 complement(2297744..2297750) /Source="Nicolas_upshift_promotors" /id="U1820" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=749 /SigmaFactorBS="tgcatcgttatattaataatttacgagaatttacGGTTTTTt attcatgaaaaaaAGGAATAACTCATATGAATgaatagattcatattggctggaggtt t" /listShort="ypuD" /GFF_Attribute="listLong" /label="promotor_-35" S_feature 2297758..2298680 /Source="Nicolas_S_feature" /locus_tag="new_2432160_2433082" /HighExp="S5, S4, S6, S8, S7, C30, S3, C90, BT, BC" /AntisenseName="sipS" /AntisenseCor="-0.46666993867379197" /AntisenseRegPval="-15.2" /CDS_PredictionProba="NA" /TUshortSig="SigEF" /TUshortPSig="0.998" /TUlongSig="NA" /TUlongPSig="NA" /label="S882" upshifts 2297758 /Source="Nicolas_upshifts" /id="U1821" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=1077 /SigmaFactorBS="tatgaatctattcattcatatgagttattcctttttttcaTG AATAaaaaaccgtaaattcTCGTAAATTATTAATATAAcgatgcataacgggaatatg t" /listShort="S882" /GFF_Attribute="listLong" promotor_-10 2297759..2297777 /Source="Nicolas_upshift_promotors" /id="U1821" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=1077 /SigmaFactorBS="tatgaatctattcattcatatgagttattcctttttttcaTG AATAaaaaaccgtaaattcTCGTAAATTATTAATATAAcgatgcataacgggaatatg t" /listShort="S882" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-10 complement(2297765..2297780) /Source="Nicolas_upshift_promotors" /id="U1822" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1641 /SigmaFactorBS="atagaaaagaaatttttgcagaaatgTGAAACATATtcccgt tatgcaTCGTTATATTAATAATttacgagaatttacggttttttattcatgaaaaaaa g" /listShort="ypuD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2297768) /Source="Nicolas_upshifts" /id="U1822" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1641 /SigmaFactorBS="atagaaaagaaatttttgcagaaatgTGAAACATATtcccgt tatgcaTCGTTATATTAATAATttacgagaatttacggttttttattcatgaaaaaaa g" /listShort="ypuD" /GFF_Attribute="listLong" S_feature complement(2297770..2297836) /Source="Nicolas_S_feature" /locus_tag="new_2432172_2432238_c" /HighExp="Etha, T1.30H, M9-stat, T0.30H, M40t90, T2.30H, MG-0.2, MG 15, HiTm, T3.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigI, SigA" /TUshortPSig="1, 0.994" /TUlongSig="SigA" /TUlongPSig="0.97" /label="S883" promotor_-35 complement(2297793..2297802) /Source="Nicolas_upshift_promotors" /id="U1822" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1641 /SigmaFactorBS="atagaaaagaaatttttgcagaaatgTGAAACATATtcccgt tatgcaTCGTTATATTAATAATttacgagaatttacggttttttattcatgaaaaaaa g" /listShort="ypuD" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(2297831..2297839) /Source="Nicolas_upshift_promotors" /id="U1823" /multdbtbs="-" /comp="M2" /sig="SigI" /pcomp=1 /psig=1 /xcortree=1769 /SigmaFactorBS="ttggggctgctttttttatatcttttttacggtcaTCCCCTA AAaacagaacataaaTTCGTATATctatagaaaagaaatttttgcagaaatgtgaaac a" /listShort="S883, ypuD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2297836) /Source="Nicolas_upshifts" /id="U1823" /multdbtbs="-" /comp="M2" /sig="SigI" /pcomp=1 /psig=1 /xcortree=1769 /SigmaFactorBS="ttggggctgctttttttatatcttttttacggtcaTCCCCTA AAaacagaacataaaTTCGTATATctatagaaaagaaatttttgcagaaatgtgaaac a" /listShort="S883, ypuD" /GFF_Attribute="listLong" promotor_-35 complement(2297853..2297861) /Source="Nicolas_upshift_promotors" /id="U1823" /multdbtbs="-" /comp="M2" /sig="SigI" /pcomp=1 /psig=1 /xcortree=1769 /SigmaFactorBS="ttggggctgctttttttatatcttttttacggtcaTCCCCTA AAaacagaacataaaTTCGTATATctatagaaaagaaatttttgcagaaatgtgaaac a" /listShort="S883, ypuD" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2297914..2298468) /gene="sipS" /locus_tag="BSU_23310" /old_locus_tag="BSU23310" /EC_number="3.4.21.89" /function="16.2: Construct biomass (Anabolism)" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:8282190, 9325333, 9694797, 9823656, 10198007, 10336490, 10982814, 11004175, 11309398, 15502345" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8282190, 9325333, 9694797, 9823656, 10198007, 10336490, 10982814, 11004175, 11309398, 15502345; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="type I signal peptidase" /protein_id="NP_390212.1" /db_xref="EnsemblGenomes-Gn:BSU23310" /db_xref="EnsemblGenomes-Tr:CAB14263" /db_xref="GOA:P28628" /db_xref="InterPro:IPR000223" /db_xref="InterPro:IPR015927" /db_xref="InterPro:IPR019756" /db_xref="InterPro:IPR019757" /db_xref="InterPro:IPR019758" /db_xref="InterPro:IPR036286" /db_xref="SubtiList:BG10515" /db_xref="UniProtKB/Swiss-Prot:P28628" /translation="MKSENVSKKKSILEWAKAIVIAVVLALLIRNFIFAPYVVDGDSM YPTLHNRERVFVNMTVKYIGEFDRGDIVVLNGDDVHYVKRIIGLPGDTVEMKNDQLYI NGKKVDEPYLAANKKRAKQDGFDHLTDDFGPVKVPDNKYFVMGDNRRNSMDSRNGLGL FTKKQIAGTSKFVFYPFNEMRKTN*" gene complement(2297914..2298468) /gene="sipS" /locus_tag="BSU_23310" /old_locus_tag="BSU23310" downshifts complement(2297924) /Source="Nicolas_upshifts" /id="D1218" /incds=0 /nref=195 /ntot=252 /MaxReadThrough="3.6233" /MaxDrop="7.24702" /score="30.4586783" /energy="-10.9" /TU="U1824" /idTUdmin="U1825" /TUdmin="-2" /isTUend="TRUE" promotor_-10 complement(2298494..2298513) /Source="Nicolas_upshift_promotors" /id="U1824" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.901098901098901" /psig="0.994005994005994" /xcortree=3155 /SigmaFactorBS="atgaagattaacagtttgtaaaatcacttcaatggtcctaaT GGGATTttttttcgattCGTGATAACATAAATTGAAGaccgttgtttattggaggaaa t" /listShort="sipS, S883, ypuD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2298512) /Source="Nicolas_upshifts" /id="U1824" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.901098901098901" /psig="0.994005994005994" /xcortree=3155 /SigmaFactorBS="atgaagattaacagtttgtaaaatcacttcaatggtcctaaT GGGATTttttttcgattCGTGATAACATAAATTGAAGaccgttgtttattggaggaaa t" /listShort="sipS, S883, ypuD" /GFF_Attribute="listLong" S_feature complement(2298514..2298913) /Source="Nicolas_S_feature" /locus_tag="new_2432916_2433315_c" /HighExp="T4.0H, T2.30H, T5.0H, T3.0H, T2.0H, T3.30H, M9-stat, C90, BC, T1.30H" /AntisenseName="ypzC" /AntisenseCor="-0.215992681600812" /AntisenseRegPval="-3.4" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.97" /TUlongSig="NA" /TUlongPSig="NA" /label="S884" promotor_-35 complement(2298525..2298531) /Source="Nicolas_upshift_promotors" /id="U1824" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.901098901098901" /psig="0.994005994005994" /xcortree=3155 /SigmaFactorBS="atgaagattaacagtttgtaaaatcacttcaatggtcctaaT GGGATTttttttcgattCGTGATAACATAAATTGAAGaccgttgtttattggaggaaa t" /listShort="sipS, S883, ypuD" /GFF_Attribute="listLong" /label="promotor_-35" CDS 2298735..2298971 /gene="ypzC" /locus_tag="BSU_23320" /old_locus_tag="BSU23320" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="NP_390213.1" /db_xref="EnsemblGenomes-Gn:BSU23320" /db_xref="EnsemblGenomes-Tr:CAB14264" /db_xref="SubtiList:BG13765" /db_xref="UniProtKB/Swiss-Prot:O32012" /translation="MFIYCIPLISQSMIPMALDKTINVMKVTGMFAATYFTGDNRTPF FAFIICLKSFKLENMDQPPKNKSNIFPAVEDSLL*" gene 2298735..2298971 /gene="ypzC" /locus_tag="BSU_23320" /old_locus_tag="BSU23320" CDS complement(2298914..2299120) /gene="ypzJ" /locus_tag="BSU_23328" /old_locus_tag="BSU23328" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="YP_003097757.1" /db_xref="EnsemblGenomes-Gn:BSU23328" /db_xref="EnsemblGenomes-Tr:CAX52656" /db_xref="InterPro:IPR018652" /db_xref="UniProtKB/Swiss-Prot:C0H447" /translation="MNNKGCIKCGSTEAGQKEIATTGTGLSKLFDVQHNRFLVVYCKN CGYSEFYNKESSTAGNILDLFFGG*" gene complement(2298914..2299120) /gene="ypzJ" /locus_tag="BSU_23328" /old_locus_tag="BSU23328" misc_feature complement(2299153..2299172) /Source="Nicolas_upshift_promotors" /id="U1825" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.440559440559441" /psig="0.97002997002997" /xcortree=2780 /SigmaFactorBS="caattagtatgtaatcaaaattaagtaaactttaaagtagta cgggtcattgggattgatattTTGTAGTAAAATAAATCAAAcaaacgtgatgtaatga a" /listShort="ypzJ, S884, sipS" /listLong="S883, ypuD" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(2299175) /Source="Nicolas_upshifts" /id="U1825" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.440559440559441" /psig="0.97002997002997" /xcortree=2780 /SigmaFactorBS="caattagtatgtaatcaaaattaagtaaactttaaagtagta cgggtcattgggattgatattTTGTAGTAAAATAAATCAAAcaaacgtgatgtaatga a" /listShort="ypzJ, S884, sipS" /listLong="S883, ypuD" CDS complement(2299229..2299483) /gene="ypuC" /locus_tag="BSU_23329" /old_locus_tag="BSU23329" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /pseudo /codon_start=1 /transl_table=11 /product="fragment of hypothetical protein" /db_xref="PSEUDO:CAX52657.1" /translation="MSFLVFVLIFLFVILTRRVCKLLHFFVYYRFIPHRAEPCVLYEQ YPSDVAAGYAFGGVWLSLNVLVMELFRFSRRFTKLRNEPN*" gene complement(2299229..2299483) /gene="ypuC" /locus_tag="BSU_23329" /old_locus_tag="BSU23329" /pseudo promotor_-35 2299363..2299372 /Source="Nicolas_upshift_promotors" /id="U1826" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.995004995004995" /psig="0.995004995004995" /xcortree=1336 /SigmaFactorBS="taacccgcagcaacatcactcggatactgctcataaaGTACA CACGGctcagcccgatgaGGAATAAAACGATAATAAACaaaaaaatgcaacagtttgc a" /listShort="S885" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2299374..2299763) /gene="ypuC" /locus_tag="BSU_23330" /old_locus_tag="BSU23330" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function; PubMedId : 15849754, 16850406" /pseudo /codon_start=1 /transl_table=11 /product="fragment of hypothetical protein" /db_xref="SubtiList:BG10514" /translation="MSYWIGYRLGPAAIQKAFASRGVLLAVIVLTFFWTVFRGQDRKI ELSFLFFLVIGGELYEEGIRRLFHSLHPVHAPLESHVLYPFPSEQTLTAFVIFGFCAY LFVRHSHKTRLQTVAFFCLLSFYSSSG*" gene complement(2299374..2299763) /gene="ypuC" /locus_tag="BSU_23330" /old_locus_tag="BSU23330" /pseudo S_feature 2299386..2300457 /Source="Nicolas_S_feature" /locus_tag="new_2433788_2434859" /HighExp="S6, S8, S7, BT, S5, B36, S4, Pyr, G/S, C30" /AntisenseName="ypuC" /AntisenseCor="0.37168085148262697" /AntisenseRegPval="-9.5" /CDS_PredictionProba="0.69113899999999995" /TUshortSig="SigK" /TUshortPSig="0.995" /TUlongSig="NA" /TUlongPSig="NA" /label="S885" promotor_-10 2299386..2299405 /Source="Nicolas_upshift_promotors" /id="U1826" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.995004995004995" /psig="0.995004995004995" /xcortree=1336 /SigmaFactorBS="taacccgcagcaacatcactcggatactgctcataaaGTACA CACGGctcagcccgatgaGGAATAAAACGATAATAAACaaaaaaatgcaacagtttgc a" /listShort="S885" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2299386 /Source="Nicolas_upshifts" /id="U1826" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.995004995004995" /psig="0.995004995004995" /xcortree=1336 /SigmaFactorBS="taacccgcagcaacatcactcggatactgctcataaaGTACA CACGGctcagcccgatgaGGAATAAAACGATAATAAACaaaaaaatgcaacagtttgc a" /listShort="S885" /GFF_Attribute="listLong" CDS complement(2299741..2299944) /gene="ypuB" /locus_tag="BSU_23340" /old_locus_tag="BSU23340" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="NP_390215.1" /db_xref="EnsemblGenomes-Gn:BSU23340" /db_xref="EnsemblGenomes-Tr:CAB14266" /db_xref="SubtiList:BG10513" /db_xref="UniProtKB/Swiss-Prot:P35151" /translation="MQVLTGLLEQYGYAVLFIVLMLELLALLGPGEFAGVLVFQEKLN WVLSMLAAGLGSCGSEHVVLDRV*" gene complement(2299741..2299944) /gene="ypuB" /locus_tag="BSU_23340" /old_locus_tag="BSU23340" CDS 2300353..2300469 /locus_tag="BSU_23349" /old_locus_tag="BSU23349" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /pseudo /codon_start=1 /transl_table=11 /product="hypothetical protein" /db_xref="PSEUDO:SOX90572.1" /translation="MYMHFESAQDDPITFARKAAAAFRVVKRIDRYLGFRKL*" gene 2300353..2300469 /locus_tag="BSU_23349" /old_locus_tag="BSU23349" /pseudo downshifts 2300420 /Source="Nicolas_upshifts" /id="D1219" /incds=0 /nref=3 /ntot=18 /MaxReadThrough="-0.179729999999999" /MaxDrop="3.76747" /score="-7.5033349" /energy="-9.1" /TU="NA" /idTUdmin="U1826" /TUdmin=198 /isTUend="FALSE" promotor_-35 2300546..2300555 /Source="Nicolas_upshift_promotors" /id="U1827" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1416 /SigmaFactorBS="aaacaggcatctcctaaatatttttgccgataagtttaCGCT AATCAActctagcactaaTACATATAAAAAATAGAATGatatgaaaggagacttgata g" /listShort="ypzD" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2300568..2300587 /Source="Nicolas_upshift_promotors" /id="U1827" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1416 /SigmaFactorBS="aaacaggcatctcctaaatatttttgccgataagtttaCGCT AATCAActctagcactaaTACATATAAAAAATAGAATGatatgaaaggagacttgata g" /listShort="ypzD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2300568 /Source="Nicolas_upshifts" /id="U1827" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1416 /SigmaFactorBS="aaacaggcatctcctaaatatttttgccgataagtttaCGCT AATCAActctagcactaaTACATATAAAAAATAGAATGatatgaaaggagacttgata g" /listShort="ypzD" /GFF_Attribute="listLong" CDS 2300610..2300822 /gene="ypzD" /locus_tag="BSU_23350" /old_locus_tag="BSU23350" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="putative germination protein" /protein_id="NP_390216.1" /db_xref="EnsemblGenomes-Gn:BSU23350" /db_xref="EnsemblGenomes-Tr:CAB14267" /db_xref="InterPro:IPR019618" /db_xref="SubtiList:BG13766" /db_xref="UniProtKB/Swiss-Prot:O32013" /translation="MIDYPININNVSGNSVINVGGAFMIRPLTLSKSVFGSGGLNTGI VFENNFVSKAKMINHQFTDQNVTKTF*" gene 2300610..2300822 /gene="ypzD" /locus_tag="BSU_23350" /old_locus_tag="BSU23350" downshifts 2300816 /Source="Nicolas_upshifts" /id="D1220" /incds=0 /nref=4 /ntot=32 /MaxReadThrough="4.9048" /MaxDrop="3.6863" /score="3.56038753" /energy="-6.9" /TU="U1827" /idTUdmin="U1827" /TUdmin="-264" /isTUend="FALSE" downshifts complement(2300958) /Source="Nicolas_upshifts" /id="D1221" /incds=0 /nref=254 /ntot=263 /MaxReadThrough="2.52018" /MaxDrop="8.47213" /score="34.3429406" /energy="-12.4" /TU="NA" /idTUdmin="U1828" /TUdmin=0 /isTUend="TRUE" CDS complement(2300958..2301389) /gene="ppiB" /locus_tag="BSU_23360" /old_locus_tag="BSU23360" /EC_number="5.2.1.8" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:8639516, 9063446, 9748346, 25184565" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8639516, 9063446, 9748346, 25184565; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="peptidyl-prolyl isomerase" /protein_id="NP_390217.1" /db_xref="EnsemblGenomes-Gn:BSU23360" /db_xref="EnsemblGenomes-Tr:CAB14268" /db_xref="GOA:P35137" /db_xref="InterPro:IPR002130" /db_xref="InterPro:IPR020892" /db_xref="InterPro:IPR024936" /db_xref="InterPro:IPR029000" /db_xref="SubtiList:BG10512" /db_xref="UniProtKB/Swiss-Prot:P35137" /translation="MKTGYFLLEDGNKIEFELYPEAAPGTVANFEKLANEGFYDGLTF HRVIPGFVSQGGCPHGTGTGGPGYTIKCETEGNPHTHEAGALSMAHAGKDTGGSQFFI VHEPQPHLNGVHTVFGKVTSGLEFAKNMSNGDVMKEVRVEG*" gene complement(2300958..2301389) /gene="ppiB" /locus_tag="BSU_23360" /old_locus_tag="BSU23360" S_feature complement(2301390..2301476) /Source="Nicolas_S_feature" /locus_tag="new_2435792_2435878_c" /HighExp="dia5, dia15, dia0, Lbexp, LBGtran, C90, Lbtran, HPh, G180, Mt0" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S886" promotor_-10 complement(2301459..2301478) /Source="Nicolas_upshift_promotors" /id="U1828" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.643356643356643" /psig=1 /xcortree=2355 /SigmaFactorBS="ttcaggtttcatttttattttttagtaaagctcgggagaTTC GTTttcccccgaaaggTGTGGTATAATAGCCGCGACaaggagagacaggctataacct a" /listShort="S886, ppiB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2301476) /Source="Nicolas_upshifts" /id="U1828" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.643356643356643" /psig=1 /xcortree=2355 /SigmaFactorBS="ttcaggtttcatttttattttttagtaaagctcgggagaTTC GTTttcccccgaaaggTGTGGTATAATAGCCGCGACaaggagagacaggctataacct a" /listShort="S886, ppiB" /GFF_Attribute="listLong" promotor_-35 complement(2301492..2301497) /Source="Nicolas_upshift_promotors" /id="U1828" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.643356643356643" /psig=1 /xcortree=2355 /SigmaFactorBS="ttcaggtttcatttttattttttagtaaagctcgggagaTTC GTTttcccccgaaaggTGTGGTATAATAGCCGCGACaaggagagacaggctataacct a" /listShort="S886, ppiB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 2301526..2301535 /Source="Nicolas_upshift_promotors" /id="U1829" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1655 /SigmaFactorBS="gggggaaaacgaatctcccgagctttactaaaaaataaaaaT GAAACCTGAatctctttatctCCGTCTAACCTAACGGaactgtatttttcatgattca g" /listShort="S887, ypuA" /GFF_Attribute="listLong" /label="promotor_-35" S_feature 2301545..2301642 /Source="Nicolas_S_feature" /locus_tag="new_2435947_2436044" /HighExp="Heat, Etha, Salt, dia0, HiTm, T0.30H, B60, Lbexp, T1.0H, Oxctl" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigWXY" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S887" upshifts 2301545 /Source="Nicolas_upshifts" /id="U1829" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1655 /SigmaFactorBS="gggggaaaacgaatctcccgagctttactaaaaaataaaaaT GAAACCTGAatctctttatctCCGTCTAACCTAACGGaactgtatttttcatgattca g" /listShort="S887, ypuA" /GFF_Attribute="listLong" promotor_-10 2301548..2301563 /Source="Nicolas_upshift_promotors" /id="U1829" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1655 /SigmaFactorBS="gggggaaaacgaatctcccgagctttactaaaaaataaaaaT GAAACCTGAatctctttatctCCGTCTAACCTAACGGaactgtatttttcatgattca g" /listShort="S887, ypuA" /GFF_Attribute="listLong" /label="promotor_-10" CDS 2301643..2302515 /gene="ypuA" /locus_tag="BSU_23370" /old_locus_tag="BSU23370" /function="16.6: Maintain" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 17434969, 18179421, 24706874; Product type f: factor" /codon_start=1 /transl_table=11 /product="putative exported protein" /protein_id="NP_390218.1" /db_xref="EnsemblGenomes-Gn:BSU23370" /db_xref="EnsemblGenomes-Tr:CAB14269" /db_xref="InterPro:IPR009343" /db_xref="SubtiList:BG10511" /db_xref="UniProtKB/Swiss-Prot:P31847" /translation="MKKIWIGMLAAAVLLLMVPKVSLADAAVGDVIVTLGADLSESDK QKVLDEMNVPDNATTVTVTNKEEHEYLGKYISNAQIGSRAISSSSITIAKKGSGLNVE THNISGITDEMYLNALMTAGVKDAKVYVTAPFEVSGTAALTGLIKAYEVSSDEAISED VKQVANQELVTTSELGDKIGNENAAALIAKIKEEFAKNGVPDNKADIEKQVDDAASDL NVTLTDSQKNQLVSLFNKMKNADIDWGQVSDQLDKAKDKITKFIESDEGKNFIQKVID FFVSIWNAIVSIFK*" gene 2301643..2302515 /gene="ypuA" /locus_tag="BSU_23370" /old_locus_tag="BSU23370" downshifts 2302422 /Source="Nicolas_upshifts" /id="D1222" /incds=1 /nref=1 /ntot=1 /MaxReadThrough="5.9994" /MaxDrop="4.15288" /score="27.7277161" /energy="-12.7" /TU="U1829" /idTUdmin="U1829" /TUdmin="-66" /isTUend="FALSE" downshifts 2302488 /Source="Nicolas_upshifts" /id="D1223" /incds=0 /nref=104 /ntot=219 /MaxReadThrough="1.98749" /MaxDrop="5.95835" /score="27.7277161" /energy="-12.7" /TU="NA" /idTUdmin="U1829" /TUdmin=0 /isTUend="TRUE" CDS complement(2302545..2303864) /gene="lysA" /locus_tag="BSU_23380" /old_locus_tag="BSU23380" /EC_number="4.1.1.20" /experiment="publication(s) with functional evidences, PMID:9044297, 14627808" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9044297, 14627808; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="meso-2,6-diaminopimelate decarboxylase" /protein_id="NP_390219.1" /db_xref="EnsemblGenomes-Gn:BSU23380" /db_xref="EnsemblGenomes-Tr:CAB14270" /db_xref="GOA:P23630" /db_xref="InterPro:IPR000183" /db_xref="InterPro:IPR002986" /db_xref="InterPro:IPR009006" /db_xref="InterPro:IPR022643" /db_xref="InterPro:IPR022644" /db_xref="InterPro:IPR022653" /db_xref="InterPro:IPR022657" /db_xref="InterPro:IPR029066" /db_xref="SubtiList:BG10510" /db_xref="UniProtKB/Swiss-Prot:P23630" /translation="MFLHGTSRQNQHGHLEIGGVDALYLAEKYGTPLYVYDVALIRER AKSFKQAFISAGLKAQVAYASKAFSSVAMIQLAEEEGLSLDVVSGGELYTAVAAGFPA ERIHFHGNNKSREELRMALEHRIGCIVVDNFYEIALLEDLCKETGHSIDVLLRITPGV EAHTHDYITTGQEDSKFGFDLHNGQTERAIEQVLQSEHIQLLGVHCHIGSQIFDTAGF VLAAEKIFKKLDEWRDSYSFVSKVLNLGGGFGIRYTEDDEPLHATEYVEKIIEAVKEN ASRYGFDIPEIWIEPGRSLVGDAGTTLYTVGSQKEVPGVRQYVAVDGGMNDNIRPALY QAKYEAAAANRIGEAHDKTVSIAGKCCESGDMLIWDIDLPEVKEGDLLAVFCTGAYGY SMANNYNRIPRPAVVFVENGEAHLVVKRETYEDIVKLDLPFKTGVKQ*" gene complement(2302545..2303864) /gene="lysA" /locus_tag="BSU_23380" /old_locus_tag="BSU23380" downshifts complement(2302565) /Source="Nicolas_upshifts" /id="D1224" /incds=0 /nref=192 /ntot=251 /MaxReadThrough="2.99445" /MaxDrop="5.13504" /score="28.6775009" /energy="-12.7" /TU="NA" /idTUdmin="U1830" /TUdmin=0 /isTUend="TRUE" S_feature complement(2303865..2303929) /Source="Nicolas_S_feature" /locus_tag="new_2438267_2438331_c" /HighExp="C90, HiOs, BMM, GM 120, GM 25, MG-0.2, GM 15, GM-0.2, MG t5, MG 5" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigGF" /TUshortPSig="0.996, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S888" promotor_-10 complement(2303925..2303944) /Source="Nicolas_upshift_promotors" /id="U1830" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.711288711288711" /psig="0.996003996003996" /xcortree=3075 /SigmaFactorBS="ggcagcctaccaattcataatcgCATTGAAActgactgaaga gtaTGATAATGTATGTCTTAATTatgaagggacagtccataaaactgtcctttcatcc a" /listShort="S888, lysA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2303929) /Source="Nicolas_upshifts" /id="U1830" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.711288711288711" /psig="0.996003996003996" /xcortree=3075 /SigmaFactorBS="ggcagcctaccaattcataatcgCATTGAAActgactgaaga gtaTGATAATGTATGTCTTAATTatgaagggacagtccataaaactgtcctttcatcc a" /listShort="S888, lysA" /GFF_Attribute="listLong" promotor_-35 complement(2303959..2303966) /Source="Nicolas_upshift_promotors" /id="U1830" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.711288711288711" /psig="0.996003996003996" /xcortree=3075 /SigmaFactorBS="ggcagcctaccaattcataatcgCATTGAAActgactgaaga gtaTGATAATGTATGTCTTAATTatgaagggacagtccataaaactgtcctttcatcc a" /listShort="S888, lysA" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2303970..2305451) /gene="spoVAF" /locus_tag="BSU_23390" /old_locus_tag="BSU23390" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:16077113, 17573930, 24682327, 26604257" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16077113, 17573930, 24682327, 26604257; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="stage V sporulation protein AF" /protein_id="NP_390220.2" /db_xref="EnsemblGenomes-Gn:BSU23390" /db_xref="EnsemblGenomes-Tr:CAB14271" /db_xref="GOA:P31845" /db_xref="InterPro:IPR004995" /db_xref="SubtiList:BG10508" /db_xref="UniProtKB/Swiss-Prot:P31845" /translation="MPDHKEEKIRVYRNPAKNEEYFKNRVGMGTSYDVGVRKLTILDK EIQLYYLNGLCDTAYIIHLMRELVAINNRKEDPDELVDIVENRLLNAQVEKVKTLDET TDQVLSGLVAVIVEGAGFAFIIDVRSYPGRNPEEPDTEKVVRGARDGFVENIVVNTAL LRRRIRDERLRVKMTKVGERSKTDLSICYIEDIADPDLVEIVEKEIASIDVDGLTMAD KTVEEFIVNQSYNPFPLVRYTERPDVAANHVLEGHVIIIVDTSPSVIITPTTLFHHVQ HAEEYRQAPSVGTFLRWVRFFGILASTLFLPIWFLFVLQPDLLPDNMKFIGLNKDTHI PIILQIFLADLGIEFLRMAAIHTPTALSTAMGLIAAVLIGQIAIEVGLFSPEVILYVS LAAIGTFTTPSYELSLANKMSRLVLMILVALFHIKGLVIGFTVLIIAMASIKSLQTPY LWPLIPFNGKALWQVLVRTAKPGAKVRPSIVHPKNRLRQPTNS*" gene complement(2303970..2305451) /gene="spoVAF" /locus_tag="BSU_23390" /old_locus_tag="BSU23390" misc_feature complement(2304676..2304695) /Source="Nicolas_upshift_promotors" /id="U1831" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.95004995004995" /psig="0.998001998001998" /xcortree=2143 /SigmaFactorBS="tatacagaaagaccggatgtggccgcaaatcatgttctagaa ggcCATGTTATCATTATAGTGGAcacatcgccgagtgtgatcattaccccgacgactt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(2304680) /Source="Nicolas_upshifts" /id="U1831" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.95004995004995" /psig="0.998001998001998" /xcortree=2143 /SigmaFactorBS="tatacagaaagaccggatgtggccgcaaatcatgttctagaa ggcCATGTTATCATTATAGTGGAcacatcgccgagtgtgatcattaccccgacgactt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" CDS complement(2305402..2306013) /gene="spoVAEA" /locus_tag="BSU_23401" /old_locus_tag="BSU23401" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:16077113, 17573930, 24682327, 26604257" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16077113, 17573930, 24682327, 26604257; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="stage V sporulation germinant protein" /protein_id="YP_003097758.1" /db_xref="EnsemblGenomes-Gn:BSU23401" /db_xref="EnsemblGenomes-Tr:CAX52658" /db_xref="GOA:P40870" /db_xref="InterPro:IPR025914" /db_xref="UniProtKB/Swiss-Prot:P40870" /translation="MTTKRKVILVTDGDVYAAKTIEYAASKVGGRCISQSKGNPSTRS GAELVKLIASAPYDPVFVMFDDSGLQGEGPGEAALTYVATHPSIEVLGVIAVASKTHQ AEWTRVDVSIDRNGEITEYGVDKVGEREFDDHRMSGDTVYCLDKLDLPLIVGIGDIGK MGRKDDISKGSPITMKAVEFILERSGYHAGPQGRENSGLSESS*" gene complement(2305402..2306013) /gene="spoVAEA" /locus_tag="BSU_23401" /old_locus_tag="BSU23401" CDS complement(2306021..2306371) /gene="spoVAEB" /locus_tag="BSU_23402" /old_locus_tag="BSU23402" /experiment="publication(s) with functional evidences, PMID:17573930, 26604257, 27105070" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 17573930, 26604257, 27105070; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="spore germinant protein" /protein_id="YP_003097759.1" /db_xref="EnsemblGenomes-Gn:BSU23402" /db_xref="EnsemblGenomes-Tr:CAX52659" /db_xref="GOA:C0H450" /db_xref="InterPro:IPR005562" /db_xref="InterPro:IPR014204" /db_xref="UniProtKB/Swiss-Prot:C0H450" /translation="MDYLLAFVCGGAICIVGQLLLDIFKLTPAHVMTSFVVIGAILDG FGIYDKFIEFAGGGATVPIVSFGHSLLHGAMHQAHIHGFIGIGMGIFELTSAGISAAI LFAFIVAVIFKPKG*" gene complement(2306021..2306371) /gene="spoVAEB" /locus_tag="BSU_23402" /old_locus_tag="BSU23402" CDS complement(2306373..2307389) /gene="spoVAD" /locus_tag="BSU_23410" /old_locus_tag="BSU23410" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:16077113, 22328679, 26604257, 27105070" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16077113, 22328679, 26604257, 27105070; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="stage V sporulation protein AD (uptake of pyridine-2,6-dicarboxylic acid)" /protein_id="NP_390222.1" /db_xref="EnsemblGenomes-Gn:BSU23410" /db_xref="EnsemblGenomes-Tr:CAB14273" /db_xref="GOA:P40869" /db_xref="InterPro:IPR010894" /db_xref="InterPro:IPR016039" /db_xref="PDB:3LM6" /db_xref="SubtiList:BG10895" /db_xref="UniProtKB/Swiss-Prot:P40869" /translation="MKLTGKQTWVFEHPIFVNSAGTAAGPKEKDGPLGSLFDKTYDEM HCNQKSWEMAERQLMEDAVNVALQKNNLTKDDIDLLLAGDLLNQNVTANYVARHLKIP FLCMFGACSTSMETVAVASALVDGGFAKRALAATSSHNATAERQFRYPTEYGGQKPDT ATSTVTGSGAVVISQTPGDIQITSATVGKVSDLGITDPFDMGSAMAPAAADTIKQHFK DLNRTADDYDLILTGDLSGVGSPIVKDILKEDGYPVGTKHDDCGLLIYTPDQQVFAGG SGCACSAVVTYSHIFKQLREGKLNRVFVVATGALLSPTMIQQKETIPTIAHGVVFERA GGAS*" gene complement(2306373..2307389) /gene="spoVAD" /locus_tag="BSU_23410" /old_locus_tag="BSU23410" promotor_-35 2306869..2306876 /Source="Nicolas_upshift_promotors" /id="U1832" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.711288711288711" /psig="0.987012987012987" /xcortree=627 /SigmaFactorBS="tatcacccggtgtctgaCTGATGACaactgcaccgcttCCGG TTACAGTGGAGGTAGCagtgtccggtttttggcctccgtattctgtcggatagcgaaa c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2306890..2306909 /Source="Nicolas_upshift_promotors" /id="U1832" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.711288711288711" /psig="0.987012987012987" /xcortree=627 /SigmaFactorBS="tatcacccggtgtctgaCTGATGACaactgcaccgcttCCGG TTACAGTGGAGGTAGCagtgtccggtttttggcctccgtattctgtcggatagcgaaa c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2306912 /Source="Nicolas_upshifts" /id="U1832" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.711288711288711" /psig="0.987012987012987" /xcortree=627 /SigmaFactorBS="tatcacccggtgtctgaCTGATGACaactgcaccgcttCCGG TTACAGTGGAGGTAGCagtgtccggtttttggcctccgtattctgtcggatagcgaaa c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" CDS complement(2307402..2307854) /gene="spoVAC" /locus_tag="BSU_23420" /old_locus_tag="BSU23420" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:15849754, 16077113, 16850406, 24666282, 26604257, 27105070" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15849754, 16077113, 16850406, 24666282, 26604257, 27105070; Product type cp : cell process" /codon_start=1 /transl_table=11 /product="mechanosensitive channel; stage V sporulation protein AC" /protein_id="NP_390223.1" /db_xref="EnsemblGenomes-Gn:BSU23420" /db_xref="EnsemblGenomes-Tr:CAB14274" /db_xref="GOA:P40868" /db_xref="InterPro:IPR005562" /db_xref="InterPro:IPR014203" /db_xref="SubtiList:BG10894" /db_xref="UniProtKB/Swiss-Prot:P40868" /translation="MTNIKENYKSKVKTYQPKPPYVWNCVKAFLVGGLICAIGQGLQN FYIHFFDFNEKTAGNPTAATLILISALLTGFGIYDRIGQFAGAGSAVPVTGFANSMAS AALEYKSEGLVLGVATNMFKLAGNVIVFGVVAAYIVGMIRFAFEKLMS*" gene complement(2307402..2307854) /gene="spoVAC" /locus_tag="BSU_23420" /old_locus_tag="BSU23420" CDS complement(2307867..2308292) /gene="spoVAB" /locus_tag="BSU_23430" /old_locus_tag="BSU23430" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:15849754, 16077113, 16850406, 26604257" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15849754, 16077113, 16850406, 26604257; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="stage V sporulation protein AB" /protein_id="NP_390224.1" /db_xref="EnsemblGenomes-Gn:BSU23430" /db_xref="EnsemblGenomes-Tr:CAB14275" /db_xref="GOA:P40867" /db_xref="InterPro:IPR020144" /db_xref="SubtiList:BG10893" /db_xref="UniProtKB/Swiss-Prot:P40867" /translation="MIVSVLFIIFVGLGGGITVGAGFVAFLTVMGIIPRLMQLTKTMR FVQAYEAAVILGAVCGGWETLHMNHLYLTKWIAVPVGLLAGLFVGMLAAALTEVLNVL PILAKRIGLRSKIIILLMAIVIGKIAGSLFHWLYFIDHS*" gene complement(2307867..2308292) /gene="spoVAB" /locus_tag="BSU_23430" /old_locus_tag="BSU23430" CDS complement(2308282..2308902) /gene="spoVAA" /locus_tag="BSU_23440" /old_locus_tag="BSU23440" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:3114420, 26604257" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 3114420, 26604257; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="stage V sporulation protein AA" /protein_id="NP_390225.2" /db_xref="EnsemblGenomes-Gn:BSU23440" /db_xref="EnsemblGenomes-Tr:CAB14276" /db_xref="GOA:P40866" /db_xref="InterPro:IPR021997" /db_xref="SubtiList:BG10892" /db_xref="UniProtKB/Swiss-Prot:P40866" /translation="MERRIFIRLRHRVLAHPGDIITVGDAAQIEGQLQLKKKLSAMPL YQVSEKDKNIVILDIIQVLRAIHLQDPTIDVQTVGGAETIVEIQYRKRNLSTVLFIGV WLLLFIGSCLAIMNFHEDVSMRDVHIALYEIITGERNDYPYLLQIPYSIGLGLGMIVF FNHIFKKRLNEEPSPLEVEMFNYQLDLDQYVAMHENQETIKDLHDR*" gene complement(2308282..2308902) /gene="spoVAA" /locus_tag="BSU_23440" /old_locus_tag="BSU23440" promotor_-10 complement(2308933..2308944) /Source="Nicolas_upshift_promotors" /id="U1833" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=924 /SigmaFactorBS="tgtgcaaaagcgtggtaatttatggtcttttcgagcggaTGA ATGAgaacaaaatcgaaCCACATACTACAtatataaccaccgaaagatggtgatcaat g" /listShort="spoVAA, spoVAB, spoVAC, spoVAD, spoVAEB, spoVAEA, spoVAF, S888, lysA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2308943) /Source="Nicolas_upshifts" /id="U1833" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=924 /SigmaFactorBS="tgtgcaaaagcgtggtaatttatggtcttttcgagcggaTGA ATGAgaacaaaatcgaaCCACATACTACAtatataaccaccgaaagatggtgatcaat g" /listShort="spoVAA, spoVAB, spoVAC, spoVAD, spoVAEB, spoVAEA, spoVAF, S888, lysA" /GFF_Attribute="listLong" promotor_-35 complement(2308958..2308964) /Source="Nicolas_upshift_promotors" /id="U1833" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=924 /SigmaFactorBS="tgtgcaaaagcgtggtaatttatggtcttttcgagcggaTGA ATGAgaacaaaatcgaaCCACATACTACAtatataaccaccgaaagatggtgatcaat g" /listShort="spoVAA, spoVAB, spoVAC, spoVAD, spoVAEB, spoVAEA, spoVAF, S888, lysA" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2309027..2309794) /gene="sigF" /locus_tag="BSU_23450" /old_locus_tag="BSU23450" /function="16.5: Explore" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:9891799, 15187183, 15205417, 15819616, 16045607, 22115775, 23169620, 24067622, 26506528" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9891799, 15187183, 15205417, 15819616, 16045607, 22115775, 23169620, 24067622, 26506528; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="RNA polymerase sporulation-specific sigma factor(sigma-F)" /protein_id="NP_390226.1" /db_xref="EnsemblGenomes-Gn:BSU23450" /db_xref="EnsemblGenomes-Tr:CAB14277" /db_xref="GOA:P07860" /db_xref="InterPro:IPR000943" /db_xref="InterPro:IPR007624" /db_xref="InterPro:IPR007627" /db_xref="InterPro:IPR007630" /db_xref="InterPro:IPR013324" /db_xref="InterPro:IPR013325" /db_xref="InterPro:IPR014236" /db_xref="InterPro:IPR014284" /db_xref="InterPro:IPR014322" /db_xref="InterPro:IPR036388" /db_xref="SubtiList:BG10298" /db_xref="UniProtKB/Swiss-Prot:P07860" /translation="MDVEVKKNGKNAQLKDHEVKELIKQSQNGDQQARDLLIEKNMRL VWSVVQRFLNRGYEPDDLFQIGCIGLLKSVDKFDLTYDVRFSTYAVPMIIGEIQRFIR DDGTVKVSRSLKELGNKIRRAKDELSKTLGRVPTVQEIADHLEIEAEDVVLAQEAVRA PSSIHETVYENDGDPITLLDQIADNSEEKWFDKIALKEAISDLEEREKLIVYLRYYKD QTQSEVAERLGISQVQVSRLEKKILKQIKVQMDHTDG*" gene complement(2309027..2309794) /gene="sigF" /locus_tag="BSU_23450" /old_locus_tag="BSU23450" downshifts complement(2309057) /Source="Nicolas_upshifts" /id="D1225" /incds=0 /nref=89 /ntot=197 /MaxReadThrough="1.81932" /MaxDrop="7.16571" /score="21.6169221" /energy="-13.5" /TU="NA" /idTUdmin="U1834" /TUdmin=1 /isTUend="TRUE" CDS complement(2309806..2310246) /gene="spoIIAB" /locus_tag="BSU_23460" /old_locus_tag="BSU23460" /EC_number="2.7.11.-" /function="16.5: Explore" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:15023063, 15187183, 15819616, 16166546, 16824103, 22115775" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15023063, 15187183, 15819616, 16166546, 16824103, 22115775; Product type cp : cell process" /codon_start=1 /transl_table=11 /product="anti-sigma factor (antagonist of sigma(F)) and serine kinase" /protein_id="NP_390227.1" /db_xref="EnsemblGenomes-Gn:BSU23460" /db_xref="EnsemblGenomes-Tr:CAB14278" /db_xref="GOA:P10728" /db_xref="InterPro:IPR003594" /db_xref="InterPro:IPR010194" /db_xref="InterPro:IPR036890" /db_xref="SubtiList:BG10297" /db_xref="UniProtKB/Swiss-Prot:P10728" /translation="MKNEMHLEFSALSQNESFARVTVASFIAQLDPTMDELTEIKTVV SEAVTNAIIHGYEENCEGKVYISVTLEDHVVYMTIRDEGLGITDLEEARQPLFTTKPE LERSGMGFTIMENFMDDVSIDSSPEMGTTIRLTKHLSKSKALCN*" gene complement(2309806..2310246) /gene="spoIIAB" /locus_tag="BSU_23460" /old_locus_tag="BSU23460" CDS complement(2310243..2310596) /gene="spoIIAA" /locus_tag="BSU_23470" /old_locus_tag="BSU23470" /function="16.5: Explore" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:11173484, 15819616, 16824103, 22115775" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11173484, 15819616, 16824103, 22115775; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="anti-anti-sigma factor (antagonist of SpoIIAB)" /protein_id="NP_390228.1" /db_xref="EnsemblGenomes-Gn:BSU23470" /db_xref="EnsemblGenomes-Tr:CAB14279" /db_xref="GOA:P10727" /db_xref="InterPro:IPR002645" /db_xref="InterPro:IPR003658" /db_xref="InterPro:IPR014237" /db_xref="InterPro:IPR036513" /db_xref="PDB:1AUZ" /db_xref="PDB:1BUZ" /db_xref="SubtiList:BG10296" /db_xref="UniProtKB/Swiss-Prot:P10727" /translation="MSLGIDMNVKESVLCIRLTGELDHHTAETLKQKVTQSLEKDDIR HIVLNLEDLSFMDSSGLGVILGRYKQIKQIGGEMVVCAISPAVKRLFDMSGLFKIIRF EQSEQQALLTLGVAS*" gene complement(2310243..2310596) /gene="spoIIAA" /locus_tag="BSU_23470" /old_locus_tag="BSU23470" promotor_-10 complement(2310621..2310639) /Source="Nicolas_upshift_promotors" /id="U1834" /multdbtbs="SigH" /comp="M1" /sig="SigH" /pcomp=1 /psig=1 /xcortree=445 /SigmaFactorBS="attatgccgaatgaccactagttttgtcacggtGAAGGAATT cattccgtcgaAATCGAAACACTCATTATCcgatcatatcaaggaggaatgagcatga g" /listShort="spoIIAA, spoIIAB, sigF" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2310632) /Source="Nicolas_upshifts" /id="U1834" /multdbtbs="SigH" /comp="M1" /sig="SigH" /pcomp=1 /psig=1 /xcortree=445 /SigmaFactorBS="attatgccgaatgaccactagttttgtcacggtGAAGGAATT cattccgtcgaAATCGAAACACTCATTATCcgatcatatcaaggaggaatgagcatga g" /listShort="spoIIAA, spoIIAB, sigF" /GFF_Attribute="listLong" S_feature complement(2310634..2310691) /Source="Nicolas_S_feature" /locus_tag="new_2445036_2445093_c" /HighExp="S4, S3, S7, S5, S8, S6, T5.0H, BT, LoTm, T4.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigGF" /TUshortPSig="0.859" /TUlongSig="NA" /TUlongPSig="NA" /label="S889" promotor_-35 complement(2310651..2310659) /Source="Nicolas_upshift_promotors" /id="U1834" /multdbtbs="SigH" /comp="M1" /sig="SigH" /pcomp=1 /psig=1 /xcortree=445 /SigmaFactorBS="attatgccgaatgaccactagttttgtcacggtGAAGGAATT cattccgtcgaAATCGAAACACTCATTATCcgatcatatcaaggaggaatgagcatga g" /listShort="spoIIAA, spoIIAB, sigF" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2310692..2311861) /gene="dacF" /locus_tag="BSU_23480" /old_locus_tag="BSU23480" /EC_number="3.4.16.4" /function="16.8: Protect" /function="16.5: Explore" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:8021191, 8936302, 9864321, 19189487" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8021191, 8936302, 9864321, 19189487; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="D-alanyl-D-alanine carboxypeptidase (penicilin binding protein)" /protein_id="NP_390229.1" /db_xref="EnsemblGenomes-Gn:BSU23480" /db_xref="EnsemblGenomes-Tr:CAB14280" /db_xref="GOA:P38422" /db_xref="InterPro:IPR001967" /db_xref="InterPro:IPR012338" /db_xref="InterPro:IPR012907" /db_xref="InterPro:IPR015956" /db_xref="InterPro:IPR018044" /db_xref="InterPro:IPR037167" /db_xref="SubtiList:BG10295" /db_xref="UniProtKB/Swiss-Prot:P38422" /translation="MKRLLSTLLIGIMLLTFAPSAFAKQDGKRTSELAHEAKSAVLIE RDTGKVLYNKNSNERLAPASMTKIMTMLLIMEALDKGKIKMSDKVRTSEHAASMGGSQ IFLEPGEEMTVKEMLKGIAIASGNDASVAMAEFISGSEEEFVKKMNKKAKELGLKNTS FKNPTGLTEEGHYSSAYDMAIMAKELLKYESITKFTGTYEDYLRENTDKKFWLVNTNR LIKFYPGVDGVKTGYTGEAKYCLTASAKKGNMRAIAVVFGASTPKERNAQVTKMLDFA FSQYETHPLYKRNQTVAKVKVKKGKQKFIELTTSEPISILTKKGEDMNDVKKEIKMKD NISAPIQKGQELGTLVLKKDGEVLAESPVAAKEDMKKAGFITFLKRTMGDWTKFK*" gene complement(2310692..2311861) /gene="dacF" /locus_tag="BSU_23480" /old_locus_tag="BSU23480" promotor_-10 complement(2311890..2311901) /Source="Nicolas_upshift_promotors" /id="U1835" /multdbtbs="SigF,SigG" /comp="M8" /sig="SigGF" /pcomp="0.85914085914086" /psig="0.85914085914086" /xcortree=1155 /SigmaFactorBS="tgtctttttttatgcccaaaattcgaaacattttccatcagt ggCGTATAAaaccatcacgcttGGAAAAAATAAAaaggattatgaaatggagggcttt t" /listShort="dacF, S889, spoIIAA, spoIIAB, sigF" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2311905) /Source="Nicolas_upshifts" /id="U1835" /multdbtbs="SigF,SigG" /comp="M8" /sig="SigGF" /pcomp="0.85914085914086" /psig="0.85914085914086" /xcortree=1155 /SigmaFactorBS="tgtctttttttatgcccaaaattcgaaacattttccatcagt ggCGTATAAaaccatcacgcttGGAAAAAATAAAaaggattatgaaatggagggcttt t" /listShort="dacF, S889, spoIIAA, spoIIAB, sigF" /GFF_Attribute="listLong" promotor_-35 complement(2311915..2311921) /Source="Nicolas_upshift_promotors" /id="U1835" /multdbtbs="SigF,SigG" /comp="M8" /sig="SigGF" /pcomp="0.85914085914086" /psig="0.85914085914086" /xcortree=1155 /SigmaFactorBS="tgtctttttttatgcccaaaattcgaaacattttccatcagt ggCGTATAAaaccatcacgcttGGAAAAAATAAAaaggattatgaaatggagggcttt t" /listShort="dacF, S889, spoIIAA, spoIIAB, sigF" /GFF_Attribute="listLong" /label="promotor_-35" downshifts complement(2312007) /Source="Nicolas_upshifts" /id="D1226" /incds=0 /nref=243 /ntot=267 /MaxReadThrough="0.87114" /MaxDrop="7.5376" /score="26.8559416" /energy="-16.7" /TU="NA" /idTUdmin="U1836" /TUdmin="-1" /isTUend="TRUE" CDS complement(2312016..2312831) /gene="pupG" /locus_tag="BSU_23490" /old_locus_tag="BSU23490" /EC_number="2.4.2.1" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:10537218, 15530033, 21279421, 21543875" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10537218, 15530033, 21279421, 21543875; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="purine nucleoside phosphorylase" /protein_id="NP_390230.1" /db_xref="EnsemblGenomes-Gn:BSU23490" /db_xref="EnsemblGenomes-Tr:CAB14281" /db_xref="GOA:P46354" /db_xref="InterPro:IPR000845" /db_xref="InterPro:IPR011268" /db_xref="InterPro:IPR011270" /db_xref="InterPro:IPR018099" /db_xref="InterPro:IPR035994" /db_xref="SubtiList:BG11330" /db_xref="UniProtKB/Swiss-Prot:P46354" /translation="MKDRIERAAAFIKQNLPESPKIGLILGSGLGILADEIENPVKLK YEDIPEFPVSTVEGHAGQLVLGTLEGVSVIAMQGRFHFYEGYSMEKVTFPVRVMKALG VEALIVTNAAGGVNTEFRAGDLMIITDHINFMGTNPLIGPNEADFGARFPDMSSAYDK DLSSLAEKIAKDLNIPIQKGVYTAVTGPSYETPAEVRFLRTMGSDAVGMSTVPEVIVA NHAGMRVLGISCISNAAAGILDQPLSHDEVMEVTEKVKAGFLKLVKAIVAQYE*" gene complement(2312016..2312831) /gene="pupG" /locus_tag="BSU_23490" /old_locus_tag="BSU23490" CDS complement(2312844..2314028) /gene="deoB" /locus_tag="BSU_23500" /old_locus_tag="BSU23500" /EC_number="5.4.2.7" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:10537218, 26211718" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10537218, 26211718; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="1,5-phosphopentomutase" /protein_id="NP_390231.2" /db_xref="EnsemblGenomes-Gn:BSU23500" /db_xref="EnsemblGenomes-Tr:CAB14282" /db_xref="GOA:P46353" /db_xref="InterPro:IPR006124" /db_xref="InterPro:IPR010045" /db_xref="InterPro:IPR017849" /db_xref="InterPro:IPR017850" /db_xref="InterPro:IPR024052" /db_xref="SubtiList:BG11331" /db_xref="UniProtKB/Swiss-Prot:P46353" /translation="MPAYKYNRVFLIVMDSVGIGEAPDAADFNDEGAHTLGHIAEHMN GLHMPNMAKLGLGLIEDIKGVEKTEHPLAYYGKMQEASNGKDTMTGHWEIMGLYIDKP FKVFPEGFPDELLQELEKRSGRKIIGNKPASGTAILDELGQEHMETGALIVYTSADSV LQIAAHEEVVPLEELYRICETARELTLDPKYMVGRIIARPFVGEPGQFKRTPNRHDYA LKPFDRTVMNELKDCGLDVISIGKISDIYDGEGITSSRRTVSNMDGMDKVIDTLGEDF TGLSFANLVDFDALFGHRRDPEGYGRALEEFDARLPEVFEKMREDDLLIITADHGNDP IHHGTDHTREYVPILAYSKKHKKAQMLPLADTFADIGATIADNFQTNKPKYGKSFLSL LQ*" gene complement(2312844..2314028) /gene="deoB" /locus_tag="BSU_23500" /old_locus_tag="BSU23500" promotor_-10 complement(2314077..2314096) /Source="Nicolas_upshift_promotors" /id="U1836" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.725274725274725" /psig=1 /xcortree=1806 /SigmaFactorBS="acagaaaatattgaagtttctcattatttccaaataCATTGT CAacgggaatgaaaacgGTTTATACTTGAGTTGTCAGacctcttagcgatacaataga c" /listShort="drm, pupG" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2314095) /Source="Nicolas_upshifts" /id="U1836" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.725274725274725" /psig=1 /xcortree=1806 /SigmaFactorBS="acagaaaatattgaagtttctcattatttccaaataCATTGT CAacgggaatgaaaacgGTTTATACTTGAGTTGTCAGacctcttagcgatacaataga c" /listShort="drm, pupG" /GFF_Attribute="listLong" S_feature complement(2314097..2314188) /Source="Nicolas_S_feature" /locus_tag="new_2448499_2448590_c" /HighExp="S3, S4, M0t90, G180, S7, S8, Glucon, G135, S5, LoTm" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigB, SigEF, SigA" /TUshortPSig="1, 1, 1, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S890" promotor_-35 complement(2314112..2314119) /Source="Nicolas_upshift_promotors" /id="U1836" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.725274725274725" /psig=1 /xcortree=1806 /SigmaFactorBS="acagaaaatattgaagtttctcattatttccaaataCATTGT CAacgggaatgaaaacgGTTTATACTTGAGTTGTCAGacctcttagcgatacaataga c" /listShort="drm, pupG" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2314189..2315079) /gene="ripX" /locus_tag="BSU_23510" /old_locus_tag="BSU23510" /function="16.9: Replicate" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:10498718, 11134515, 11208805, 16553881, 16597952, 21239579, 23305333" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10498718, 11134515, 11208805, 16553881, 16597952, 21239579, 23305333; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="site-specific tyrosine recombinase for chromosome partitioning" /protein_id="NP_390232.2" /db_xref="EnsemblGenomes-Gn:BSU23510" /db_xref="EnsemblGenomes-Tr:CAB14283" /db_xref="GOA:P46352" /db_xref="InterPro:IPR002104" /db_xref="InterPro:IPR004107" /db_xref="InterPro:IPR010998" /db_xref="InterPro:IPR011010" /db_xref="InterPro:IPR011932" /db_xref="InterPro:IPR013762" /db_xref="InterPro:IPR023009" /db_xref="SubtiList:BG11332" /db_xref="UniProtKB/Swiss-Prot:P46352" /translation="MKDQIKDFIHYVMVERGLSQNTIVSYERDLKSYSLYLTETLHVT DWNHVTRIHIIQYLKHLKDSGKSGKTSARHLASIRSFHQFLLREKVTDKDPSVHIETQ KTERALPKVLALNEVERLLDTPKLTSPFGYRDKAMLELLYATGIRVSEMIELKTADVH LSMGFIRCFGKGRKERIVPIGEAAASAIEEYMTKARGKLLKNNVSDALFLNHHGKQIS RQGFWKNLKKIALEAGIKKELTPHTLRHSFATHLLENGADLRAVQEMLGHADISTTQI YTHVTKTRLKDVYKQFHPRA*" gene complement(2314189..2315079) /gene="ripX" /locus_tag="BSU_23510" /old_locus_tag="BSU23510" CDS complement(2315087..2315314) /gene="yqzK" /locus_tag="BSU_23519" /old_locus_tag="BSU23519" /function="18: Unknown function" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 22720735" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="YP_003097760.1" /db_xref="EnsemblGenomes-Gn:BSU23519" /db_xref="EnsemblGenomes-Tr:CAX52660" /db_xref="GOA:C0H451" /db_xref="InterPro:IPR025321" /db_xref="UniProtKB/Swiss-Prot:C0H451" /translation="MGRFLKTAVDALKVFILFTGFTALFYYAMIWVNQEYENYHRYDK PEGSAVKVVEMDQDEKGGWFDRLIFFYQNGE*" gene complement(2315087..2315314) /gene="yqzK" /locus_tag="BSU_23519" /old_locus_tag="BSU23519" promotor_-10 complement(2315217..2315236) /Source="Nicolas_upshift_promotors" /id="U1837" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.835164835164835" /psig=1 /xcortree=3146 /SigmaFactorBS="cgatgcattgaaagttttcatcctgtttaccGGTTTTACcgc tttgttctatTATGCTATGATATGGGTGAAtcaagagtatgaaaactatcatcggtat g" /listShort="ripX, S890, drm, pupG" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2315228) /Source="Nicolas_upshifts" /id="U1837" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.835164835164835" /psig=1 /xcortree=3146 /SigmaFactorBS="cgatgcattgaaagttttcatcctgtttaccGGTTTTACcgc tttgttctatTATGCTATGATATGGGTGAAtcaagagtatgaaaactatcatcggtat g" /listShort="ripX, S890, drm, pupG" /GFF_Attribute="listLong" promotor_-35 complement(2315250..2315257) /Source="Nicolas_upshift_promotors" /id="U1837" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.835164835164835" /psig=1 /xcortree=3146 /SigmaFactorBS="cgatgcattgaaagttttcatcctgtttaccGGTTTTACcgc tttgttctatTATGCTATGATATGGGTGAAtcaagagtatgaaaactatcatcggtat g" /listShort="ripX, S890, drm, pupG" /GFF_Attribute="listLong" /label="promotor_-35" upshifts complement(2315307) /Source="Nicolas_upshifts" /id="U1838" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=180 /SigmaFactorBS="atttggcatatGGTTTATataactggaaccataGGGAAAGGA TCGATTAGGAcatgggaagattcctgaaaacagctgtcgatgcattgaaagttttcat c" /listShort="yqzK, ripX, S890, drm, pupG" /GFF_Attribute="listLong" promotor_-10 complement(2315316..2315334) /Source="Nicolas_upshift_promotors" /id="U1838" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=180 /SigmaFactorBS="atttggcatatGGTTTATataactggaaccataGGGAAAGGA TCGATTAGGAcatgggaagattcctgaaaacagctgtcgatgcattgaaagttttcat c" /listShort="yqzK, ripX, S890, drm, pupG" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-10 complement(2315344..2315362) /Source="Nicolas_upshift_promotors" /id="U1839" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1165 /SigmaFactorBS="ttctcatggggaaagggttttttgctgtttctaTGTATAaaa cctttctgatttgGCATATGGTTTATATAACTggaaccatagggaaaggatcgattag g" /listShort="yqzK, ripX, S890, drm, pupG" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 complement(2315350..2315356) /Source="Nicolas_upshift_promotors" /id="U1838" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=180 /SigmaFactorBS="atttggcatatGGTTTATataactggaaccataGGGAAAGGA TCGATTAGGAcatgggaagattcctgaaaacagctgtcgatgcattgaaagttttcat c" /listShort="yqzK, ripX, S890, drm, pupG" /GFF_Attribute="listLong" /label="promotor_-35" upshifts complement(2315357) /Source="Nicolas_upshifts" /id="U1839" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1165 /SigmaFactorBS="ttctcatggggaaagggttttttgctgtttctaTGTATAaaa cctttctgatttgGCATATGGTTTATATAACTggaaccatagggaaaggatcgattag g" /listShort="yqzK, ripX, S890, drm, pupG" /GFF_Attribute="listLong" promotor_-35 complement(2315379..2315384) /Source="Nicolas_upshift_promotors" /id="U1839" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1165 /SigmaFactorBS="ttctcatggggaaagggttttttgctgtttctaTGTATAaaa cctttctgatttgGCATATGGTTTATATAACTggaaccatagggaaaggatcgattag g" /listShort="yqzK, ripX, S890, drm, pupG" /GFF_Attribute="listLong" /label="promotor_-35" downshifts complement(2315439) /Source="Nicolas_upshifts" /id="D1227" /incds=0 /nref=159 /ntot=251 /MaxReadThrough="4.06128" /MaxDrop="5.73495" /score="5.40881961" /energy="-8.1" /TU="U1840" /idTUdmin="U1841" /TUdmin=506 /isTUend="FALSE" CDS complement(2315439..2315888) /gene="fur" /locus_tag="BSU_23520" /old_locus_tag="BSU23520" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:12029044, 12374814, 14563870, 15802251, 16672620, 25160631, 25209494" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12029044, 12374814, 14563870, 15802251, 16672620, 25160631, 25209494; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator for iron transport andmetabolism" /protein_id="NP_390233.2" /db_xref="EnsemblGenomes-Gn:BSU23520" /db_xref="EnsemblGenomes-Tr:CAB14284" /db_xref="GOA:P54574" /db_xref="InterPro:IPR002481" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG11766" /db_xref="UniProtKB/Swiss-Prot:P54574" /translation="MENRIDRIKKQLHSSSYKLTPQREATVRVLLENEEDHLSAEDVY LLVKEKSPEIGLATVYRTLELLTELKVVDKINFGDGVSRYDLRKEGAAHFHHHLVCME CGAVDEIEEDLLEDVEEIIERDWKFKIKDHRLTFHGICHRCNGKETE*" gene complement(2315439..2315888) /gene="fur" /locus_tag="BSU_23520" /old_locus_tag="BSU23520" promotor_-10 complement(2315912..2315931) /Source="Nicolas_upshift_promotors" /id="U1840" /multdbtbs="SigA" /comp="M16" /sig="SigA" /pcomp="0.893106893106893" /psig=1 /xcortree=2743 /SigmaFactorBS="accattttatttatcagtttataataattatAGTTGgaactc tgcgcgtatTTTGTTATAATGAGTCATGGaatgcggcgtaggagggaaagacatggaa a" /listShort="fur, yqzK, ripX, S890" /listLong="drm, pupG" /label="promotor_-10" upshifts complement(2315922) /Source="Nicolas_upshifts" /id="U1840" /multdbtbs="SigA" /comp="M16" /sig="SigA" /pcomp="0.893106893106893" /psig=1 /xcortree=2743 /SigmaFactorBS="accattttatttatcagtttataataattatAGTTGgaactc tgcgcgtatTTTGTTATAATGAGTCATGGaatgcggcgtaggagggaaagacatggaa a" /listShort="fur, yqzK, ripX, S890" /listLong="drm, pupG" S_feature complement(2315924..2316000) /Source="Nicolas_S_feature" /locus_tag="new_2450326_2450402_c" /HighExp="S3, S4, S5, BT, LoTm, M9-stat, T5.0H, T3.30H, T4.0H, T3.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigEF" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S891" promotor_-35 complement(2315947..2315951) /Source="Nicolas_upshift_promotors" /id="U1840" /multdbtbs="SigA" /comp="M16" /sig="SigA" /pcomp="0.893106893106893" /psig=1 /xcortree=2743 /SigmaFactorBS="accattttatttatcagtttataataattatAGTTGgaactc tgcgcgtatTTTGTTATAATGAGTCATGGaatgcggcgtaggagggaaagacatggaa a" /listShort="fur, yqzK, ripX, S890" /listLong="drm, pupG" /label="promotor_-35" CDS complement(2316001..2316645) /gene="spoIIM" /locus_tag="BSU_23530" /old_locus_tag="BSU23530" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:15849754, 16850406, 17376078, 17824930, 20382772, 23859254" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15849754, 16850406, 17376078, 17824930, 20382772, 23859254; Product type cp : cell process" /codon_start=1 /transl_table=11 /product="autolysin component for dissolution of the septal cell wall (stage II sporulation)" /protein_id="NP_390234.1" /db_xref="EnsemblGenomes-Gn:BSU23530" /db_xref="EnsemblGenomes-Tr:CAB14285" /db_xref="GOA:P37873" /db_xref="InterPro:IPR002798" /db_xref="InterPro:IPR014196" /db_xref="SubtiList:BG10768" /db_xref="UniProtKB/Swiss-Prot:P37873" /translation="MRKISYKDMFLRHVKDHLSLYIFVSVLFFMGVIFGAIIVNSMTI SQKEDLYYYLSQFFGQLSDGKQASSADMFGQSIFHNAKYLGLMWILGISVIGMPIIFI MIFLKGIVVGFTVGFLVNQMGVSGFFLSFVSVLPQNVLLIPAYLIMGTCAIAFSLKLI RQLFVKRSLHDAPIQWFGRYAFVLLVILFLALISSLFEAYLSPVLMEKLTSRLF*" gene complement(2316001..2316645) /gene="spoIIM" /locus_tag="BSU_23530" /old_locus_tag="BSU23530" promotor_-10 complement(2316676..2316694) /Source="Nicolas_upshift_promotors" /id="U1841" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=995 /SigmaFactorBS="ccgcctagcattcatctctattgtttctttttgaaaaagGGC ATGtttttctgtttcttTCATACAATCTATTAAATCaaatcactagagcgggcgggag g" /listShort="spoIIM, S891" /listLong="fur" /label="promotor_-10" upshifts complement(2316693) /Source="Nicolas_upshifts" /id="U1841" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=995 /SigmaFactorBS="ccgcctagcattcatctctattgtttctttttgaaaaagGGC ATGtttttctgtttcttTCATACAATCTATTAAATCaaatcactagagcgggcgggag g" /listShort="spoIIM, S891" /listLong="fur" promotor_-35 complement(2316709..2316714) /Source="Nicolas_upshift_promotors" /id="U1841" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=995 /SigmaFactorBS="ccgcctagcattcatctctattgtttctttttgaaaaagGGC ATGtttttctgtttcttTCATACAATCTATTAAATCaaatcactagagcgggcgggag g" /listShort="spoIIM, S891" /listLong="fur" /label="promotor_-35" CDS complement(2316746..2316961) /gene="yqkK" /locus_tag="BSU_23540" /old_locus_tag="BSU23540" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_390235.1" /db_xref="EnsemblGenomes-Gn:BSU23540" /db_xref="EnsemblGenomes-Tr:CAB14286" /db_xref="SubtiList:BG11765" /db_xref="UniProtKB/Swiss-Prot:P54573" /translation="MAKSQAKKKRGHRLRNGGRDVLLSRGSTPSFSTHGRMTKSKKEI LNKRKHKNPYDHTAVDDKDFFVPQKAA*" gene complement(2316746..2316961) /gene="yqkK" /locus_tag="BSU_23540" /old_locus_tag="BSU23540" downshifts complement(2316826) /Source="Nicolas_upshifts" /id="D1228" /incds=1 /nref=17 /ntot=130 /MaxReadThrough="0.857610000000001" /MaxDrop="3.7055" /score="1.77181315" /energy="-9.8" /TU="NA" /idTUdmin="U1842" /TUdmin="-1" /isTUend="TRUE" CDS complement(2317061..2318380) /gene="mleA" /locus_tag="BSU_23550" /old_locus_tag="BSU23550" /EC_number="1.1.1.38" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:16788182, 23136871" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16788182, 23136871; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="catabolic NAD-dependent malic enzyme (conversionof malate into pyruvate)" /protein_id="NP_390236.1" /db_xref="EnsemblGenomes-Gn:BSU23550" /db_xref="EnsemblGenomes-Tr:CAB14287" /db_xref="GOA:P54572" /db_xref="InterPro:IPR001891" /db_xref="InterPro:IPR002912" /db_xref="InterPro:IPR006140" /db_xref="InterPro:IPR012301" /db_xref="InterPro:IPR012302" /db_xref="InterPro:IPR015884" /db_xref="InterPro:IPR036291" /db_xref="InterPro:IPR037062" /db_xref="SubtiList:BG11764" /db_xref="UniProtKB/Swiss-Prot:P54572" /translation="MIAKHMIRTLMIETPSVPGNLGRVATAIGLLGGDIGEVETVKVG PNYTMRNITVQVENEEQLQEVIAAVQALGEGIRLHTVSDEVLSAHEGGKIQMKSKMPI RSLAELGRVYTPGVADVCRLIEKEPEKASIYTTISNSVAIVTDGTAILGLGNIGSVAG MPVMEGKAALFDQLAGISGIPILLDTSDPEEIIKTVKHISPGFSGILLEDIGSPHCFE IEDRLKEELNIPVMHDDQHGTAVVTLAAAISACRSAGVDLKEAKVGQIGLGAAGVAIC RMFMAYGVNAVYGTDKSESAMNRLEQYGGQAVSSIEELMETCDIVIATTGVPGLIKPA FVRSGQVILALSNPKPEIEPEAALQAGAAYAADGRSVNNVLGFPGIFRGALNAKSTEI NHDMLVAAAEAIAACTKQGDVVPQPLDSKVHHAVAAAVEHAALTAVK*" gene complement(2317061..2318380) /gene="mleA" /locus_tag="BSU_23550" /old_locus_tag="BSU23550" downshifts complement(2317068) /Source="Nicolas_upshifts" /id="D1229" /incds=0 /nref=29 /ntot=84 /MaxReadThrough="3.50516" /MaxDrop="5.65279" /score="42.1653011" /energy="-15.2" /TU="U1842,U1843" /idTUdmin="U1842" /TUdmin="-243" /isTUend="FALSE" CDS complement(2318398..2319804) /gene="mleN" /locus_tag="BSU_23560" /old_locus_tag="BSU23560" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:10903309, 15849754, 16850406" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10903309, 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="malate-H+/Na+-lactate antiporter" /protein_id="NP_390237.1" /db_xref="EnsemblGenomes-Gn:BSU23560" /db_xref="EnsemblGenomes-Tr:CAB14288" /db_xref="GOA:P54571" /db_xref="InterPro:IPR004770" /db_xref="InterPro:IPR018461" /db_xref="SubtiList:BG11763" /db_xref="UniProtKB/Swiss-Prot:P54571" /translation="MKDVRLPTLFEIIIVLGVFLALVLSFTVFLDLPIQLALFVSWFI AMLLGIRLGYSYKDLQNAIVHGISNGLEAVLILVSVGALIGTWIAGGVVPTLIYYGLE FIHPSIFLLATLIICSIMSVATGTSWGTVGTAGIAMIAIGEGLGIPLPLVAGAILSGA YFGDKLSPLSDSTVLASSLSKVDVLAHVRAMLYLSIPAYVITAILFTVVGFMYGGKNI DLDKVEFLKSSLQNTFDIHIWMLIPAVLVIVLLAMKKPSMPVIVIGALLGAIWAVVFQ GMDIAHAIATAYNGFSIKTDVEFLNGLLNRGGIVGMLDSLVVIIFGLGFGGLLEKLGV LKVIVSTFEKKLTSAGNVTLSTLIVAFLANIFGCAMYVSLILTPKIMEDSYDRLHLDR RVLSRNSEVGGTLTSGMVPWSDNGIYMAGILGVSTFSYLPFMWLSFVAIGLAIIYGYT GKFIWYTKNNTVKAEKLG*" gene complement(2318398..2319804) /gene="mleN" /locus_tag="BSU_23560" /old_locus_tag="BSU23560" promotor_-10 complement(2319852..2319871) /Source="Nicolas_upshift_promotors" /id="U1842" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.964035964035964" /psig="0.998001998001998" /xcortree=2714 /SigmaFactorBS="tcatctccgaatagtcggatgaataagcTGTTTACAacatag ggatgaggAAGTATAGTATACGTGTTGCactatatattgaaagcgttttagcttttac a" /listShort="mleN, mleA, yqkK" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2319861) /Source="Nicolas_upshifts" /id="U1842" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.964035964035964" /psig="0.998001998001998" /xcortree=2714 /SigmaFactorBS="tcatctccgaatagtcggatgaataagcTGTTTACAacatag ggatgaggAAGTATAGTATACGTGTTGCactatatattgaaagcgttttagcttttac a" /listShort="mleN, mleA, yqkK" /GFF_Attribute="listLong" S_feature complement(2319863..2319944) /Source="Nicolas_S_feature" /locus_tag="new_2454265_2454346_c" /HighExp="S0, dia0, dia5, Lbexp, G150, Oxctl, G135, Mt0, Paraq, LBGexp" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="1, 0.937" /TUlongSig="NA" /TUlongPSig="NA" /label="S892" promotor_-35 complement(2319886..2319893) /Source="Nicolas_upshift_promotors" /id="U1842" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.964035964035964" /psig="0.998001998001998" /xcortree=2714 /SigmaFactorBS="tcatctccgaatagtcggatgaataagcTGTTTACAacatag ggatgaggAAGTATAGTATACGTGTTGCactatatattgaaagcgttttagcttttac a" /listShort="mleN, mleA, yqkK" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2319945..2321372) /gene="ansB" /locus_tag="BSU_23570" /old_locus_tag="BSU23570" /EC_number="4.3.1.1" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:1711029" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1711029; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="L-aspartase (aspartate ammonia lyase)" /protein_id="NP_390238.2" /db_xref="EnsemblGenomes-Gn:BSU23570" /db_xref="EnsemblGenomes-Tr:CAB14289" /db_xref="GOA:P26899" /db_xref="InterPro:IPR000362" /db_xref="InterPro:IPR004708" /db_xref="InterPro:IPR008948" /db_xref="InterPro:IPR018951" /db_xref="InterPro:IPR020557" /db_xref="InterPro:IPR022761" /db_xref="InterPro:IPR024083" /db_xref="SubtiList:BG10301" /db_xref="UniProtKB/Swiss-Prot:P26899" /translation="MLNGQKEYRVEKDFLGEKQIEADVYYGIQTLRASENFPITGYKI HEEMINALAIVKKAAALANMDVKRLYEGIGQAIVQAADEILEGKWHDQFIVDPIQGGA GTSMNMNANEVIGNRALEIMGHKKGDYIHLSPNTHVNMSQSTNDVFPTAIHISTLKLL EKLLKTMEDMHSVFKQKAQEFDSVIKMGRTHLQDAVPIRLGQEFEAYSRVLERDIKRI KQSRQHLYEVNMGATAVGTGLNADPEYIKQVVKHLADISGLPLVGADHLVDATQNTDA YTEVSASLKVCMMNMSKIANDLRLMASGPRAGLAEISLPARQPGSSIMPGKVNPVMAE LINQIAFQVIGNDNTICLASEAGQLELNVMEPVLVFNLLQSISIMNNGFRSFTDNCLK GIEANEKRMKQYVEKSAGVITAVNPHLGYEAAARIAREAIMTGQSVRDLCLQHDVLTE EELDIILNPYEMTKPGIAGKELLEK*" gene complement(2319945..2321372) /gene="ansB" /locus_tag="BSU_23570" /old_locus_tag="BSU23570" CDS complement(2321417..2322406) /gene="ansA" /locus_tag="BSU_23580" /old_locus_tag="BSU23580" /EC_number="3.5.1.1" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:1711029, 11914346, 22720735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1711029, 11914346, 22720735; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="exported L-asparaginase" /protein_id="NP_390239.1" /db_xref="EnsemblGenomes-Gn:BSU23580" /db_xref="EnsemblGenomes-Tr:CAB14290" /db_xref="GOA:P26900" /db_xref="InterPro:IPR006033" /db_xref="InterPro:IPR006034" /db_xref="InterPro:IPR020827" /db_xref="InterPro:IPR027473" /db_xref="InterPro:IPR027474" /db_xref="InterPro:IPR027475" /db_xref="InterPro:IPR036152" /db_xref="InterPro:IPR037152" /db_xref="SubtiList:BG10300" /db_xref="UniProtKB/Swiss-Prot:P26900" /translation="MKKLLMLTTGGTIASVEGENGLAPGVKADELLSYVSKLDNDYTM ETQSLMNIDSTNMQPEYWVEIAEAVKENYDAYDGFVITHGTDTMAYTSAALSYMLQHA KKPIVITGSQIPITFQKTDAKKNITDAIRFACEGVGGVYVVFDGRVIQGTRAIKLRTK SYDAFESINYPYIAFINEDGIEYNKQVTEPENDTFTVDTSLCTDVCLLKLHPGLKPEM FDALKSMYKGIVIESYGSGGVPFEGRDILSKVNELIESGIVVVITTQCLEEGEDMSIY EVGRRVNQDLIIRSRNMNTEAIVPKLMWALGQSSDLPVVKRIMETPIADDVVL*" gene complement(2321417..2322406) /gene="ansA" /locus_tag="BSU_23580" /old_locus_tag="BSU23580" S_feature complement(2322407..2322486) /Source="Nicolas_S_feature" /locus_tag="new_2456809_2456888_c" /HighExp="dia0, Lbexp, G150, Oxctl, dia5, LBGexp, Paraq, C30, G180, H2O2" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="1, 0.937" /TUlongSig="NA" /TUlongPSig="NA" /label="S893" promotor_-10 complement(2322468..2322487) /Source="Nicolas_upshift_promotors" /id="U1843" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.808191808191808" /psig=1 /xcortree=1807 /SigmaFactorBS="taggtattaggaagtgtacgcgaattgaataataatgTCTTG CGTattttattttccgtGTCTATAATTGCATTAAAAGtatgcgaaaagcgaatacctt c" /listShort="S893, ansA, ansB, S892, mleN, mleA, yqkK" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2322486) /Source="Nicolas_upshifts" /id="U1843" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.808191808191808" /psig=1 /xcortree=1807 /SigmaFactorBS="taggtattaggaagtgtacgcgaattgaataataatgTCTTG CGTattttattttccgtGTCTATAATTGCATTAAAAGtatgcgaaaagcgaatacctt c" /listShort="S893, ansA, ansB, S892, mleN, mleA, yqkK" /GFF_Attribute="listLong" S_feature complement(2322488..2322808) /Source="Nicolas_S_feature" /locus_tag="new_2456890_2457210_c" /HighExp="LBGstat, S5, G135, S8, S6, LBGtran, G180, G150, LoTm, LBGexp" /AntisenseName="ansR" /AntisenseCor="0.23077291929287899" /AntisenseRegPval="-3.9" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.937" /TUlongSig="NA" /TUlongPSig="NA" /label="S894" promotor_-35 complement(2322502..2322509) /Source="Nicolas_upshift_promotors" /id="U1843" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.808191808191808" /psig=1 /xcortree=1807 /SigmaFactorBS="taggtattaggaagtgtacgcgaattgaataataatgTCTTG CGTattttattttccgtGTCTATAATTGCATTAAAAGtatgcgaaaagcgaatacctt c" /listShort="S893, ansA, ansB, S892, mleN, mleA, yqkK" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 2322527..2322534 /Source="Nicolas_upshift_promotors" /id="U1844" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.525474525474525" /psig="0.998001998001998" /xcortree=2183 /SigmaFactorBS="cggaaaataaaatacgcaagacattattattcaattcgCGTA CACTtcctaatacctaTATGATATAATCAGCTCAAGgtgaaaaaggagcggaagttca t" /listShort="ansR" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2322547..2322566 /Source="Nicolas_upshift_promotors" /id="U1844" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.525474525474525" /psig="0.998001998001998" /xcortree=2183 /SigmaFactorBS="cggaaaataaaatacgcaagacattattattcaattcgCGTA CACTtcctaatacctaTATGATATAATCAGCTCAAGgtgaaaaaggagcggaagttca t" /listShort="ansR" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2322549 /Source="Nicolas_upshifts" /id="U1844" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.525474525474525" /psig="0.998001998001998" /xcortree=2183 /SigmaFactorBS="cggaaaataaaatacgcaagacattattattcaattcgCGTA CACTtcctaatacctaTATGATATAATCAGCTCAAGgtgaaaaaggagcggaagttca t" /listShort="ansR" /GFF_Attribute="listLong" CDS 2322588..2322938 /gene="ansR" /locus_tag="BSU_23590" /old_locus_tag="BSU23590" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:11914346" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11914346; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator of ansAB (Xre family)" /protein_id="NP_390240.1" /db_xref="EnsemblGenomes-Gn:BSU23590" /db_xref="EnsemblGenomes-Tr:CAB14291" /db_xref="GOA:Q07683" /db_xref="InterPro:IPR001387" /db_xref="InterPro:IPR010982" /db_xref="InterPro:IPR027910" /db_xref="SubtiList:BG10299" /db_xref="UniProtKB/Swiss-Prot:Q07683" /translation="MNLDRLTELRKKKNWSLQYTADLLGIAKSTYAGYESGYRRPSLE ALAMLADLFDTTCDELLGREKQKQTAPQAIELATWSSLDFTISVDGQPLSEDEIIQLI TFIRTKRKVQEELS*" gene 2322588..2322938 /gene="ansR" /locus_tag="BSU_23590" /old_locus_tag="BSU23590" S_feature complement(2322810..2322946) /Source="Nicolas_S_feature" /locus_tag="new_2457212_2457348_c" /HighExp="LBGstat, S8, S6, S7, S5, ferm, nit, LBGtran, BT, LPhT" /AntisenseName="ansR" /AntisenseCor="-0.22421651781702501" /AntisenseRegPval="-3.7" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.937" /TUlongSig="NA" /TUlongPSig="NA" /label="S895" downshifts complement(2322853) /Source="Nicolas_upshifts" /id="D1230" /incds=1 /nref=4 /ntot=116 /MaxReadThrough="3.90926" /MaxDrop="4.76642" /score="10.2434094" /energy="-23.6" /TU="U1847" /idTUdmin="U1845" /TUdmin=1451 /isTUend="FALSE" CDS complement(2322947..2324110) /gene="yqxK" /locus_tag="BSU_23600" /old_locus_tag="BSU23600" /function="16.11: Scavenge (Catabolism)" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type f: factor" /codon_start=1 /transl_table=11 /product="putative nucleotide binding protein" /protein_id="NP_390241.2" /db_xref="EnsemblGenomes-Gn:BSU23600" /db_xref="EnsemblGenomes-Tr:CAB14292" /db_xref="GOA:P38423" /db_xref="InterPro:IPR005287" /db_xref="InterPro:IPR010994" /db_xref="InterPro:IPR016195" /db_xref="SubtiList:BG11073" /db_xref="UniProtKB/Swiss-Prot:P38423" /translation="MKKIYADLHIHIGRTFTGRAVKITGAKTLTLDRILVEASEHKGI ELLGIIDCHSPEVILELEEGISSGKYRELDGGGIRYRSTTLLLGSELEIYDEACSGPI HVLVFMPTLADMKQFSNWLSARLKNIHLSSQRIYETGLNLQKKVQDMGGLFIPAHIFT PHKSLYGKGVKSSLTEVFDPSMIDAVELGLSCDTDMASHVSQLNPYPFLTNSDAHSLG KIGREYNELYVQSADFTEFALALKGQDDRKIIANYGLDPLLGKYYQTACEACGEPAVS GETACANCGKARFTKGVSDRLRELSDQLEVRVPRPRYVHQIPLQFVPGVGPKTLDKLK KAFGTEMAVLHEAAEEDLARVVPPKTAALIVKARSGKLELKAGGGGTYGKIKP*" gene complement(2322947..2324110) /gene="yqxK" /locus_tag="BSU_23600" /old_locus_tag="BSU23600" CDS complement(2324107..2324664) /gene="nudF" /locus_tag="BSU_23610" /old_locus_tag="BSU23610" /EC_number="3.1.7.1" /EC_number="3.6.1.13" /function="16.6: Maintain" /function="16.11: Scavenge (Catabolism)" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 10542272, 17693564, 21638333, 25212876; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="isopentenyl pyrophosphate and dimethylallyl pyrophosphate diphosphatase (moonlighting ADP-ribose pyrophosphatase)" /protein_id="NP_390242.1" /db_xref="EnsemblGenomes-Gn:BSU23610" /db_xref="EnsemblGenomes-Tr:CAB14293" /db_xref="GOA:P54570" /db_xref="InterPro:IPR000086" /db_xref="InterPro:IPR015797" /db_xref="InterPro:IPR020084" /db_xref="InterPro:IPR020476" /db_xref="SubtiList:BG11762" /db_xref="UniProtKB/Swiss-Prot:P54570" /translation="MKSLEEKTIAKEQIFSGKVIDLYVEDVELPNGKASKREIVKHPG AVAVLAVTDEGKIIMVKQFRKPLERTIVEIPAGKLEKGEEPEYTALRELEEETGYTAK KLTKITAFYTSPGFADEIVHVFLAEELSVLEEKRELDEDEFVEVMEVTLEDALKLVES REVYDAKTAYAIQYLQLKEALQAQK*" gene complement(2324107..2324664) /gene="nudF" /locus_tag="BSU_23610" /old_locus_tag="BSU23610" promotor_no_box complement(2324594..2324694) /Source="Nicolas_upshift_promotors" /id="U1845" /multdbtbs="-" /comp="M21" /sig="Sig-" /pcomp="0.688311688311688" /psig="0.01998001998002" /xcortree=1733 /SigmaFactorBS="tcatatagagacagaacgggagatgaagaaatgaaatcatta gaagaaaaaacaattgccaaagaacagattttttcgggtaaagtcattgatctttatg t" /listShort="nudF" /GFF_Attribute="listLong" /label="promotor_no_box" upshifts complement(2324634) /Source="Nicolas_upshifts" /id="U1845" /multdbtbs="-" /comp="M21" /sig="Sig-" /pcomp="0.688311688311688" /psig="0.01998001998002" /xcortree=1733 /SigmaFactorBS="tcatatagagacagaacgggagatgaagaaatgaaatcatta gaagaaaaaacaattgccaaagaacagattttttcgggtaaagtcattgatctttatg t" /listShort="nudF" /GFF_Attribute="listLong" promotor_-35 2324678..2324683 /Source="Nicolas_upshift_promotors" /id="U1846" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.994005994005994" /psig="0.994005994005994" /xcortree=1028 /SigmaFactorBS="ttttcttctaatgatttcatttcttcatctcccGTTCTGtct ctatatgatgccCCATACATTTTATCATACTagagcaaaagggggcttcttcgtgaaa g" /listShort="S896, yqkF" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2324699..2324717 /Source="Nicolas_upshift_promotors" /id="U1846" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.994005994005994" /psig="0.994005994005994" /xcortree=1028 /SigmaFactorBS="ttttcttctaatgatttcatttcttcatctcccGTTCTGtct ctatatgatgccCCATACATTTTATCATACTagagcaaaagggggcttcttcgtgaaa g" /listShort="S896, yqkF" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-10 complement(2324701..2324715) /Source="Nicolas_upshift_promotors" /id="U1847" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.404595404595405" /psig="0.937062937062937" /xcortree=2733 /SigmaFactorBS="tccgactaagacaacaccttttggcatgcggtgcactttcac gaagaagcccccttttgcTCTAgTATGATAAAATGTATggggcatcatatagagacag a" /listShort="nudF, yqxK, S895, S894, S893, ansA, ansB, S892" /listLong="mleN, mleA, yqkK" /label="promotor_-10" upshifts 2324705 /Source="Nicolas_upshifts" /id="U1846" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.994005994005994" /psig="0.994005994005994" /xcortree=1028 /SigmaFactorBS="ttttcttctaatgatttcatttcttcatctcccGTTCTGtct ctatatgatgccCCATACATTTTATCATACTagagcaaaagggggcttcttcgtgaaa g" /listShort="S896, yqkF" /GFF_Attribute="listLong" S_feature 2324712..2324886 /Source="Nicolas_S_feature" /locus_tag="new_2459114_2459288" /HighExp="S4, S5, S3, S7, S6, LoTm, BT, T5.0H, G/S, S8" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.99962399999999996" /TUshortSig="SigEF" /TUshortPSig="0.994" /TUlongSig="NA" /TUlongPSig="NA" /label="S896" promotor_-35 complement(2324717..2324720) /Source="Nicolas_upshift_promotors" /id="U1847" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.404595404595405" /psig="0.937062937062937" /xcortree=2733 /SigmaFactorBS="tccgactaagacaacaccttttggcatgcggtgcactttcac gaagaagcccccttttgcTCTAgTATGATAAAATGTATggggcatcatatagagacag a" /listShort="nudF, yqxK, S895, S894, S893, ansA, ansB, S892" /listLong="mleN, mleA, yqkK" /label="promotor_-35" upshifts complement(2324720) /Source="Nicolas_upshifts" /id="U1847" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.404595404595405" /psig="0.937062937062937" /xcortree=2733 /SigmaFactorBS="tccgactaagacaacaccttttggcatgcggtgcactttcac gaagaagcccccttttgcTCTAgTATGATAAAATGTATggggcatcatatagagacag a" /listShort="nudF, yqxK, S895, S894, S893, ansA, ansB, S892" /listLong="mleN, mleA, yqkK" CDS 2324739..2324861 /gene="mciZ" /locus_tag="BSU_23616" /old_locus_tag="BSU23616" /function="15.1: Cell division" /experiment="publication(s) with functional evidences, PMID:18284588, 23237472, 25848052, 27752253" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 18284588, 23237472, 25848052, 27752253; Product type f: factor" /codon_start=1 /transl_table=11 /product="cell division inhibitor" /protein_id="YP_009513976.1" /db_xref="EnsemblGenomes-Gn:BSU23616" /db_xref="EnsemblGenomes-Tr:CCQ48600" /db_xref="GOA:L8EBJ9" /db_xref="InterPro:IPR025177" /db_xref="PDB:2MRW" /db_xref="PDB:4U39" /db_xref="UniProtKB/TrEMBL:L8EBJ9" /translation="MKVHRMPKGVVLVGKAWEIRAKLKEYGRTFQYVKDWISKP*" gene 2324739..2324861 /gene="mciZ" /locus_tag="BSU_23616" /old_locus_tag="BSU23616" promotor_-35 2324862..2324869 /Source="Nicolas_upshift_promotors" /id="U1848" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.717282717282717" /psig="0.998001998001998" /xcortree=1920 /SigmaFactorBS="tcaatatgtgaaagattggatctcaaagccataaAAGTTGAA actttagctccttTATATTACGGTCAATACAAAgcctaaaaaaggagtgtgcacatga g" /listShort="yqkF" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2324883..2324902 /Source="Nicolas_upshift_promotors" /id="U1848" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.717282717282717" /psig="0.998001998001998" /xcortree=1920 /SigmaFactorBS="tcaatatgtgaaagattggatctcaaagccataaAAGTTGAA actttagctccttTATATTACGGTCAATACAAAgcctaaaaaaggagtgtgcacatga g" /listShort="yqkF" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2324888 /Source="Nicolas_upshifts" /id="U1848" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.717282717282717" /psig="0.998001998001998" /xcortree=1920 /SigmaFactorBS="tcaatatgtgaaagattggatctcaaagccataaAAGTTGAA actttagctccttTATATTACGGTCAATACAAAgcctaaaaaaggagtgtgcacatga g" /listShort="yqkF" /GFF_Attribute="listLong" CDS 2324924..2325844 /gene="yqkF" /locus_tag="BSU_23620" /old_locus_tag="BSU23620" /EC_number="1.1.1.-" /function="16.6: Maintain" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1c: Function from experimental evidences in the studied genus; PubMedId: 9643546, 15317791, 16242712, 24330391; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="NADPH-dependent aldo-keto reductase (acts on 4-hydroxy-2,3-trans-nonenal)" /protein_id="NP_390243.1" /db_xref="EnsemblGenomes-Gn:BSU23620" /db_xref="EnsemblGenomes-Tr:CAB14294" /db_xref="GOA:P54569" /db_xref="InterPro:IPR020471" /db_xref="InterPro:IPR023210" /db_xref="InterPro:IPR036812" /db_xref="SubtiList:BG11761" /db_xref="UniProtKB/Swiss-Prot:P54569" /translation="MRKRKLGTSDLDISEVGLGCMSLGTEKNKALSILDEAIELGINY LDTADLYDRGRNEEIVGDAIQNRRHDIILATKAGNRWDDGSEGWYWDPSKAYIKEAVK KSLTRLKTDYIDLYQLHGGTIEDNIDETIEAFEELKQEGVIRYYGISSIRPNVIKEYV KKSNIVSIMMQFSLFDRRPEEWLPLLEEHQISVVARGPVAKGLLTEKPLDQASESMKQ NGYLSYSFEELTNARKAMEEVAPDLSMTEKSLQYLLAQPAVASVITGASKIEQLRENI QAANARRLTEEEIKALQSHTKQDIYKAHRS*" gene 2324924..2325844 /gene="yqkF" /locus_tag="BSU_23620" /old_locus_tag="BSU23620" downshifts 2325833 /Source="Nicolas_upshifts" /id="D1231" /incds=0 /nref=186 /ntot=248 /MaxReadThrough="1.49159" /MaxDrop="5.81013" /score="18.6018806" /energy="-14.8" /TU="NA" /idTUdmin="U1846" /TUdmin="-1" /isTUend="TRUE" CDS complement(2325876..2326100) /gene="yqkE" /locus_tag="BSU_23630" /old_locus_tag="BSU23630" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_390244.1" /db_xref="EnsemblGenomes-Gn:BSU23630" /db_xref="EnsemblGenomes-Tr:CAB14295" /db_xref="InterPro:IPR024980" /db_xref="SubtiList:BG11760" /db_xref="UniProtKB/Swiss-Prot:P54568" /translation="MKKQKSIDKHQLKDGLQSDIKAKLMEMKSQLKEEDEKRQKREKA EQIRKKKEIEKNKSFEELLNESQMDWHQYK*" gene complement(2325876..2326100) /gene="yqkE" /locus_tag="BSU_23630" /old_locus_tag="BSU23630" downshifts complement(2325933) /Source="Nicolas_upshifts" /id="D1232" /incds=0 /nref=19 /ntot=195 /MaxReadThrough="0.59953" /MaxDrop="5.9087" /score="15.8160537" /energy="-13" /TU="NA" /idTUdmin="U1849" /TUdmin="-1" /isTUend="TRUE" promotor_-10 complement(2326123..2326142) /Source="Nicolas_upshift_promotors" /id="U1849" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.718281718281718" /psig="0.996003996003996" /xcortree=2028 /SigmaFactorBS="gctgagaaagtgatcagaagagagtcTGCTTGTTcagtttat atgctcCGTGATAAACTGGCTTCAAAacaaaacatgggggaagtctgcatgaaaaaac a" /listShort="yqkE" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2326130) /Source="Nicolas_upshifts" /id="U1849" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.718281718281718" /psig="0.996003996003996" /xcortree=2028 /SigmaFactorBS="gctgagaaagtgatcagaagagagtcTGCTTGTTcagtttat atgctcCGTGATAAACTGGCTTCAAAacaaaacatgggggaagtctgcatgaaaaaac a" /listShort="yqkE" /GFF_Attribute="listLong" promotor_-35 complement(2326157..2326164) /Source="Nicolas_upshift_promotors" /id="U1849" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.718281718281718" /psig="0.996003996003996" /xcortree=2028 /SigmaFactorBS="gctgagaaagtgatcagaagagagtcTGCTTGTTcagtttat atgctcCGTGATAAACTGGCTTCAAAacaaaacatgggggaagtctgcatgaaaaaac a" /listShort="yqkE" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 2326179..2326186 /Source="Nicolas_upshift_promotors" /id="U1850" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.7002997002997" /psig=1 /xcortree=3151 /SigmaFactorBS="tataaactgaacaagcagactctcttctgatCACTTTCTcag cgtagcagtgtTTAGGTATAATGATCTTAAAcacgaattgcctatatatttcgttgaa a" /listShort="yqkD" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2326201..2326220 /Source="Nicolas_upshift_promotors" /id="U1850" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.7002997002997" /psig=1 /xcortree=3151 /SigmaFactorBS="tataaactgaacaagcagactctcttctgatCACTTTCTcag cgtagcagtgtTTAGGTATAATGATCTTAAAcacgaattgcctatatatttcgttgaa a" /listShort="yqkD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2326208 /Source="Nicolas_upshifts" /id="U1850" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.7002997002997" /psig=1 /xcortree=3151 /SigmaFactorBS="tataaactgaacaagcagactctcttctgatCACTTTCTcag cgtagcagtgtTTAGGTATAATGATCTTAAAcacgaattgcctatatatttcgttgaa a" /listShort="yqkD" /GFF_Attribute="listLong" CDS 2326262..2327179 /gene="yqkD" /locus_tag="BSU_23640" /old_locus_tag="BSU23640" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative hydrolase" /protein_id="NP_390245.1" /db_xref="EnsemblGenomes-Gn:BSU23640" /db_xref="EnsemblGenomes-Tr:CAB14296" /db_xref="GOA:P54567" /db_xref="InterPro:IPR022742" /db_xref="InterPro:IPR029058" /db_xref="SubtiList:BG11759" /db_xref="UniProtKB/Swiss-Prot:P54567" /translation="MKKILLAIGALVTAVIAIGIVFSHMILFIKKKTDEDIIKRETDN GHDVFESFEQMEKTAFVIPSAYGYDIKGYHVAPHDTPNTIIICHGVTMNVLNSLKYMH LFLDLGWNVLIYDHRRHGQSGGKTTSYGFYEKDDLNKVVSLLKNKTNHRGLIGIHGES MGAVTALLYAGAHCSDGADFYIADCPFACFDEQLAYRLRAEYRLPSWPLLPIADFFLK LRGGYRAREVSPLAVIDKIEKPVLFIHSKDDDYIPVSSTERLYEKKRGPKALYIAENG EHAMSYTKNRHTYRKTVQEFLDNMNDSTE*" gene 2326262..2327179 /gene="yqkD" /locus_tag="BSU_23640" /old_locus_tag="BSU23640" downshifts 2327154 /Source="Nicolas_upshifts" /id="D1233" /incds=0 /nref=27 /ntot=171 /MaxReadThrough="2.02201" /MaxDrop="3.99393" /score="14.106821" /energy="-11.8" /TU="NA" /idTUdmin="U1850" /TUdmin=594 /isTUend="FALSE" CDS complement(2327219..2327458) /gene="yqkC" /locus_tag="BSU_23650" /old_locus_tag="BSU23650" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 22720735" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_390246.1" /db_xref="EnsemblGenomes-Gn:BSU23650" /db_xref="EnsemblGenomes-Tr:CAB14297" /db_xref="InterPro:IPR020157" /db_xref="SubtiList:BG11758" /db_xref="UniProtKB/Swiss-Prot:P54566" /translation="MEQKLKAMKNTAQNKTWVSFLNQNHPYTLLHWSIGGAESIKKDV WLLQDEMTFETQEFTTIDLAIEWIRENMDGITDVL*" gene complement(2327219..2327458) /gene="yqkC" /locus_tag="BSU_23650" /old_locus_tag="BSU23650" downshifts complement(2327230) /Source="Nicolas_upshifts" /id="D1234" /incds=0 /nref=215 /ntot=269 /MaxReadThrough="3.31829" /MaxDrop="6.35785" /score="16.3526162" /energy="-11.2" /TU="NA" /idTUdmin="U1851" /TUdmin=0 /isTUend="TRUE" CDS complement(2327471..2327794) /gene="yqkB" /locus_tag="BSU_23660" /old_locus_tag="BSU23660" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_390247.1" /db_xref="EnsemblGenomes-Gn:BSU23660" /db_xref="EnsemblGenomes-Tr:CAB14298" /db_xref="InterPro:IPR000361" /db_xref="InterPro:IPR035903" /db_xref="SubtiList:BG11757" /db_xref="UniProtKB/Swiss-Prot:P54565" /translation="MNIHVTDAAKQALQQAFDANPGKKAQLRYDAEGCGCAVSGVPTI WLAEELTGQCEQLETNGIPLYIQSSQKVFFDDQMTIDYNEKAKTLALKSPAEMLSPRM SILVK*" gene complement(2327471..2327794) /gene="yqkB" /locus_tag="BSU_23660" /old_locus_tag="BSU23660" promotor_-10 complement(2327537..2327556) /Source="Nicolas_upshift_promotors" /id="U1851" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.962037962037962" /psig=1 /xcortree=2731 /SigmaFactorBS="tccaatcgtcgcaaaaagtgtTTTTTGACgatcaaatgacga TCGATTACAATGAAAAAGCCaaaacattggcgctgaaaagcccggctgaaatgctcag c" /listShort="yqkC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2327538) /Source="Nicolas_upshifts" /id="U1851" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.962037962037962" /psig=1 /xcortree=2731 /SigmaFactorBS="tccaatcgtcgcaaaaagtgtTTTTTGACgatcaaatgacga TCGATTACAATGAAAAAGCCaaaacattggcgctgaaaagcccggctgaaatgctcag c" /listShort="yqkC" /GFF_Attribute="listLong" promotor_-35 complement(2327570..2327577) /Source="Nicolas_upshift_promotors" /id="U1851" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.962037962037962" /psig=1 /xcortree=2731 /SigmaFactorBS="tccaatcgtcgcaaaaagtgtTTTTTGACgatcaaatgacga TCGATTACAATGAAAAAGCCaaaacattggcgctgaaaagcccggctgaaatgctcag c" /listShort="yqkC" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2327791..2328822) /gene="yqkA" /locus_tag="BSU_23670" /old_locus_tag="BSU23670" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_390248.1" /db_xref="EnsemblGenomes-Gn:BSU23670" /db_xref="EnsemblGenomes-Tr:CAB14299" /db_xref="GOA:P54564" /db_xref="InterPro:IPR000182" /db_xref="InterPro:IPR007344" /db_xref="InterPro:IPR016181" /db_xref="SubtiList:BG11756" /db_xref="UniProtKB/Swiss-Prot:P54564" /translation="MIEFLQHKEATIAREILAVQIPAYIKETEIIGFDGIPALQEKVK DIQASHERFAGYRKNGKLIGVISYEKNMHYLTICRLVVHPDGFRKGIGRALLQFVIDH NEDAEKIEVVTAENNTPAVSLYTQAGFQKAETVKAAQGLLLSVFHLYPKRKVEIILYN EKWAECFDEEKERLKLVFGPEIIAIHHIGSTSIPNMAAKPIIDMLIEVRSIEAVSQFD EQMKANGYTPKGENGIAGRRYFQKGGNKRTHHVHMYEQGNPAIERHLLFRDYLRAHPN IAKEYAVLKKQLAAQHPDSINQYIQGKDEWIKTAEENAKRWKKGRNNANGSIVCYNSE NDENGGFTL*" gene complement(2327791..2328822) /gene="yqkA" /locus_tag="BSU_23670" /old_locus_tag="BSU23670" promotor_-10 complement(2327818..2327837) /Source="Nicolas_upshift_promotors" /id="U1852" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.957042957042957" /psig=1 /xcortree=2060 /SigmaFactorBS="atgcgaagcggtggaaaaaaggcagaaacaATGCGAATggca gtattgTATGCTACAATAGCGAAAATgatgaaaacgggggtttcaccttatgaacata c" /listShort="yqkB, yqkC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2327825) /Source="Nicolas_upshifts" /id="U1852" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.957042957042957" /psig=1 /xcortree=2060 /SigmaFactorBS="atgcgaagcggtggaaaaaaggcagaaacaATGCGAATggca gtattgTATGCTACAATAGCGAAAATgatgaaaacgggggtttcaccttatgaacata c" /listShort="yqkB, yqkC" /GFF_Attribute="listLong" promotor_-35 complement(2327848..2327855) /Source="Nicolas_upshift_promotors" /id="U1852" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.957042957042957" /psig=1 /xcortree=2060 /SigmaFactorBS="atgcgaagcggtggaaaaaaggcagaaacaATGCGAATggca gtattgTATGCTACAATAGCGAAAATgatgaaaacgggggtttcaccttatgaacata c" /listShort="yqkB, yqkC" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2328815..2329159) /gene="yqjZ" /locus_tag="BSU_23680" /old_locus_tag="BSU23680" /function="16.8: Protect" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 16267290; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative degradation enzyme (oxygenase)" /protein_id="NP_390249.1" /db_xref="EnsemblGenomes-Gn:BSU23680" /db_xref="EnsemblGenomes-Tr:CAB14300" /db_xref="InterPro:IPR007138" /db_xref="InterPro:IPR011008" /db_xref="PDB:2GO8" /db_xref="SubtiList:BG11755" /db_xref="UniProtKB/Swiss-Prot:P54563" /translation="MMDFLSKTPEPPYYAVIFSSVKSENDTGYGETAERMVSLAADQP GFLGVESVREADGRGITVSYWDSMDAINHWRHHTEHQAAKEKGRSVWYESYAVRVAKV DRQRLFQENTND*" gene complement(2328815..2329159) /gene="yqjZ" /locus_tag="BSU_23680" /old_locus_tag="BSU23680" CDS complement(2329169..2329639) /gene="yqjY" /locus_tag="BSU_23690" /old_locus_tag="BSU23690" /function="16.8: Protect" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 16267290; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative N-acetyltransferase" /protein_id="NP_390250.1" /db_xref="EnsemblGenomes-Gn:BSU23690" /db_xref="EnsemblGenomes-Tr:CAB14301" /db_xref="GOA:P54562" /db_xref="InterPro:IPR000182" /db_xref="InterPro:IPR016181" /db_xref="InterPro:IPR017255" /db_xref="PDB:1MK4" /db_xref="SubtiList:BG11754" /db_xref="UniProtKB/Swiss-Prot:P54562" /translation="MDIRTITSSDYEMVTSVLNEWWGGRQLKEKLPRLFFEHFQDTSF ITSEHNSMTGFLIGFQSQSDPETAYIHFSGVHPDFRKMQIGKQLYDVFIETVKQRGCT RVKCVTSPVNKVSIAYHTKLGFDIEKGTKTVNGISVFANYDGPGQDRVLFVKNI*" gene complement(2329169..2329639) /gene="yqjY" /locus_tag="BSU_23690" /old_locus_tag="BSU23690" S_feature complement(2329640..2329716) /Source="Nicolas_S_feature" /locus_tag="new_2464042_2464118_c" /HighExp="SMM, T-4.40H, MG 150, M9-tran, GM 90, T-3.40H, GM-0.2, M9-exp, GM 120, T-2.40H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.999" /TUlongSig="SigEF" /TUlongPSig="0.776" /label="S897" downshifts 2329640 /Source="Nicolas_upshifts" /id="D1235" /incds=0 /nref=8 /ntot=121 /MaxReadThrough="0.87367" /MaxDrop="3.61005" /score="-1.04904304" /energy="-6.5" /TU="NA" /idTUdmin="U1854" /TUdmin="-748" /isTUend="FALSE" promotor_-10 complement(2329691..2329710) /Source="Nicolas_upshift_promotors" /id="U1853" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.998001998001998" /psig="0.999000999001" /xcortree=3045 /SigmaFactorBS="ttgttccctcggcagtctggaaacgtatgatacaggaaagaa ggCATTTACAattccagccaggcaAAATATAATTTTTATATTGTgagaaaaagagctg a" /listShort="S897, yqjY, yqjZ, yqkA, yqkB, yqkC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2329716) /Source="Nicolas_upshifts" /id="U1853" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.998001998001998" /psig="0.999000999001" /xcortree=3045 /SigmaFactorBS="ttgttccctcggcagtctggaaacgtatgatacaggaaagaa ggCATTTACAattccagccaggcaAAATATAATTTTTATATTGTgagaaaaagagctg a" /listShort="S897, yqjY, yqjZ, yqkA, yqkB, yqkC" /GFF_Attribute="listLong" S_feature complement(2329718..2329824) /Source="Nicolas_S_feature" /locus_tag="new_2464120_2464226_c" /HighExp="M40t90, S4, M40t45, S6, H2O2, S5, S3, S8, S7, G135" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigEF" /TUshortPSig="0.776" /TUlongSig="NA" /TUlongPSig="NA" /label="S898" promotor_-35 complement(2329725..2329732) /Source="Nicolas_upshift_promotors" /id="U1853" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.998001998001998" /psig="0.999000999001" /xcortree=3045 /SigmaFactorBS="ttgttccctcggcagtctggaaacgtatgatacaggaaagaa ggCATTTACAattccagccaggcaAAATATAATTTTTATATTGTgagaaaaagagctg a" /listShort="S897, yqjY, yqjZ, yqkA, yqkB, yqkC" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2329825..2330163) /gene="yqjX" /locus_tag="BSU_23700" /old_locus_tag="BSU23700" /function="16.8: Protect" /function="16.5: Explore" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 12137951, 16267290" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_390251.1" /db_xref="EnsemblGenomes-Gn:BSU23700" /db_xref="EnsemblGenomes-Tr:CAB14302" /db_xref="GOA:P54561" /db_xref="InterPro:IPR014962" /db_xref="SubtiList:BG11753" /db_xref="UniProtKB/Swiss-Prot:P54561" /translation="MNDHLKRGNLLWEGSRMFLPEHKQSLLERKRLKQKLQKPILDPD KLEEMNQTLCAAMEFAQDITVSCFQDGEIVCCTGKICRYEEFEKAVWIKGDEDQLYKL KLDQVLDIVL*" gene complement(2329825..2330163) /gene="yqjX" /locus_tag="BSU_23700" /old_locus_tag="BSU23700" CDS complement(2330160..2331398) /gene="polYB" /locus_tag="BSU_23710" /old_locus_tag="BSU23710" /EC_number="2.7.7.7" /function="16.5: Explore" /function="16.9: Replicate" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:12137951, 12644484, 15469515, 16045613, 16267290, 19924481, 24118570" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12137951, 12644484, 15469515, 16045613, 16267290, 19924481, 24118570; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="Y family DNA polymerase V bypassing lesions during replication" /protein_id="NP_390252.1" /db_xref="EnsemblGenomes-Gn:BSU23710" /db_xref="EnsemblGenomes-Tr:CAB14303" /db_xref="GOA:P54560" /db_xref="InterPro:IPR001126" /db_xref="InterPro:IPR017961" /db_xref="InterPro:IPR022880" /db_xref="InterPro:IPR036775" /db_xref="SubtiList:BG11752" /db_xref="UniProtKB/Swiss-Prot:P54560" /translation="MMKEKVIFLVDMQSFYASVEKAENPHLKNRPVIVSGDPEKRGGV VLAACPLAKQKGVVNASRLWEAQEKCPEAVVLRPRMQRYIDVSLQITAILEEYTDLVE PYSIDEQFMDITGSQKLFGTPMEIAKSIQGRIMREIGVYARVGIGPNKALAKIACDNF AKKNKNGIFTLTKENMKTEMWPLPVGSMFGVGSRMKHHLNRMGISTIGGLAAFPLDLL KKKWGINGHVLWMTANGIDYSPVSTSSLDGQKAIGHGMTLPRDYEHFDKEIKVVLLEL SEEVCRRSRNAGVMGQTVSVSCRGADFDWPTGFNRQVKLAEPTNSTQDVYEAVRRLFL TFWDGKPVRRLGVNLSQLSSDDIWQLNLFQDYAKKMSLGYVMDGIKNRFGDTAIIRAA SLTAAGQAFERAAKIGGHYK*" gene complement(2330160..2331398) /gene="polYB" /locus_tag="BSU_23710" /old_locus_tag="BSU23710" misc_feature 2330322..2330323 /Source="Nicolas_upshift_promotors" /id="U1854" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.95904095904096" /psig="0.005994005994006" /xcortree=20 /SigmaFactorBS="tcacatagcctaggctcattttctttgcataatcctgaaata aattgagCTgccatatgtcatcagatgagagctgagacagattgacaccgaggcggcg g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 2330333 /Source="Nicolas_upshifts" /id="U1854" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.95904095904096" /psig="0.005994005994006" /xcortree=20 /SigmaFactorBS="tcacatagcctaggctcattttctttgcataatcctgaaata aattgagCTgccatatgtcatcagatgagagctgagacagattgacaccgaggcggcg g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" downshifts 2330388 /Source="Nicolas_upshifts" /id="D1236" /incds=1 /nref=2 /ntot=2 /MaxReadThrough="-0.14995" /MaxDrop="4.86715" /score="-1.04904304" /energy="-6.5" /TU="NA" /idTUdmin="U1854" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(2331423..2331441) /Source="Nicolas_upshift_promotors" /id="U1855" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.776223776223776" /psig="0.776223776223776" /xcortree=763 /SigmaFactorBS="tattttctgtcagacaagaatcatttaccAGTATAaaacgaa catactttcGCATATAATGAAAAGCGAAcataagttctttttagaggtgtgtatgatg a" /listShort="polYB, yqjX, S898" /listLong="S897, yqjY, yqjZ, yqkA, yqkB, yqkC" /label="promotor_-10" upshifts complement(2331432) /Source="Nicolas_upshifts" /id="U1855" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.776223776223776" /psig="0.776223776223776" /xcortree=763 /SigmaFactorBS="tattttctgtcagacaagaatcatttaccAGTATAaaacgaa catactttcGCATATAATGAAAAGCGAAcataagttctttttagaggtgtgtatgatg a" /listShort="polYB, yqjX, S898" /listLong="S897, yqjY, yqjZ, yqkA, yqkB, yqkC" promotor_-35 complement(2331458..2331463) /Source="Nicolas_upshift_promotors" /id="U1855" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.776223776223776" /psig="0.776223776223776" /xcortree=763 /SigmaFactorBS="tattttctgtcagacaagaatcatttaccAGTATAaaacgaa catactttcGCATATAATGAAAAGCGAAcataagttctttttagaggtgtgtatgatg a" /listShort="polYB, yqjX, S898" /listLong="S897, yqjY, yqjZ, yqkA, yqkB, yqkC" /label="promotor_-35" promotor_-35 2331503..2331506 /Source="Nicolas_upshift_promotors" /id="U1856" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.778221778221778" /psig=1 /xcortree=2862 /SigmaFactorBS="tgattcttgtctgacagaaaatatgatccaaggGTTTgagag aagaaaaacATTTAGTAGAATAAAAGCGAagcataaggataggagagtcatgatggag a" /listShort="yqzH" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2331521..2331540 /Source="Nicolas_upshift_promotors" /id="U1856" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.778221778221778" /psig=1 /xcortree=2862 /SigmaFactorBS="tgattcttgtctgacagaaaatatgatccaaggGTTTgagag aagaaaaacATTTAGTAGAATAAAAGCGAagcataaggataggagagtcatgatggag a" /listShort="yqzH" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2331530 /Source="Nicolas_upshifts" /id="U1856" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.778221778221778" /psig=1 /xcortree=2862 /SigmaFactorBS="tgattcttgtctgacagaaaatatgatccaaggGTTTgagag aagaaaaacATTTAGTAGAATAAAAGCGAagcataaggataggagagtcatgatggag a" /listShort="yqzH" /GFF_Attribute="listLong" CDS 2331564..2331770 /gene="yqzH" /locus_tag="BSU_23720" /old_locus_tag="BSU23720" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_390253.1" /db_xref="EnsemblGenomes-Gn:BSU23720" /db_xref="EnsemblGenomes-Tr:CAB14304" /db_xref="InterPro:IPR025546" /db_xref="SubtiList:BG13774" /db_xref="UniProtKB/Swiss-Prot:O32014" /translation="MEKFVEKMLGQALRQYGRNVAIDPLSPYEKQSLKAALQERRNEE PDEDLHAHIEDIIYDYVTNQGLFS*" gene 2331564..2331770 /gene="yqzH" /locus_tag="BSU_23720" /old_locus_tag="BSU23720" promotor_-35 2332253..2332256 /Source="Nicolas_upshift_promotors" /id="U1857" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.676323676323676" /psig="0.782217782217782" /xcortree=1401 /SigmaFactorBS="caataacgaaatattttgaacgatctATTGgagaaggaaatt ttTTCATATATGATAGAGAAAGatcatacatacaggagagaatataattcatgaagaa a" /listShort="yqjV, yqjU" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2332271..2332290 /Source="Nicolas_upshift_promotors" /id="U1857" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.676323676323676" /psig="0.782217782217782" /xcortree=1401 /SigmaFactorBS="caataacgaaatattttgaacgatctATTGgagaaggaaatt ttTTCATATATGATAGAGAAAGatcatacatacaggagagaatataattcatgaagaa a" /listShort="yqjV, yqjU" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2332287 /Source="Nicolas_upshifts" /id="U1857" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.676323676323676" /psig="0.782217782217782" /xcortree=1401 /SigmaFactorBS="caataacgaaatattttgaacgatctATTGgagaaggaaatt ttTTCATATATGATAGAGAAAGatcatacatacaggagagaatataattcatgaagaa a" /listShort="yqjV, yqjU" /GFF_Attribute="listLong" CDS 2332319..2333551 /gene="yqjV" /locus_tag="BSU_23730" /old_locus_tag="BSU23730" /function="16.1: Circulate" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 12793527, 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative efflux transporter" /protein_id="NP_390254.2" /db_xref="EnsemblGenomes-Gn:BSU23730" /db_xref="EnsemblGenomes-Tr:CAB14305" /db_xref="GOA:P54559" /db_xref="InterPro:IPR001958" /db_xref="InterPro:IPR005829" /db_xref="InterPro:IPR011701" /db_xref="InterPro:IPR020846" /db_xref="InterPro:IPR036259" /db_xref="SubtiList:BG11751" /db_xref="UniProtKB/Swiss-Prot:P54559" /translation="MKKWKDIHPISWTIIIGTIFGRMATSMSIPFLAIYLTAVQGASA SYAGLVIAASSSVGILASFYGGYISDKFGRKNMMLVSIFGWMLVFAGFAAASNLWVFF VVNALNGLCKSLFEPASKALLSDMTEEKTRLLVFNLRYAAINIGVVFGPVLGLYFGSS QSTTPFLVPAVIYGLYGIVLALQFKKHPSLSAPAQSRNMSVREAFMVTQKDYLFTIAL VGITLCTFGYSQFSSTFPQYMAQNPLIGNGTKLYGLMLTLNAIVVLATQFPIVHFAKR FSPLCSLMLGNVMVSISMAIFTVSHGVPSIVMIVITFTIGEVLLFSMMDLYVDQIAKP GLKGTYFGAIGFSQLGNVIGPWVGGICIDLFGAGRPIYIFSVLSGITLLGLPFLAFAY RQMKMETTKHRSRLEKPL*" gene 2332319..2333551 /gene="yqjV" /locus_tag="BSU_23730" /old_locus_tag="BSU23730" CDS 2333398..2333760 /gene="yqjU" /locus_tag="BSU_23740" /old_locus_tag="BSU23740" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="NP_390255.2" /db_xref="EnsemblGenomes-Gn:BSU23740" /db_xref="EnsemblGenomes-Tr:CAB14306" /db_xref="GOA:P54558" /db_xref="SubtiList:BG11750" /db_xref="UniProtKB/Swiss-Prot:P54558" /translation="MYRPVWRWPADLYFFCPERHYPARPAIFSVRLSANENGDHKTPF PSGKAALNKKRKRMNLSRKHEVKNMNIGDVMFQLFVFIIFAAVVFAAVTGFKYAKNRK AQLDRIEKKLNSLSEDHD*" gene 2333398..2333760 /gene="yqjU" /locus_tag="BSU_23740" /old_locus_tag="BSU23740" S_feature complement(2333577..2333756) /Source="Nicolas_S_feature" /locus_tag="new_2467979_2468158_c" /HighExp="Sw, BC, C90, C30, M0t90, BI, Lbtran, Lbstat, M40t45, G135" /AntisenseName="yqjU" /AntisenseCor="-0.38632421151235602" /AntisenseRegPval="-10.3" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S899" downshifts complement(2333610) /Source="Nicolas_upshifts" /id="D1237" /incds=0 /nref=59 /ntot=226 /MaxReadThrough="1.66997" /MaxDrop="4.81479" /score="21.7095422" /energy="-11.4" /TU="NA" /idTUdmin="U1858" /TUdmin=0 /isTUend="TRUE" CDS complement(2333757..2334143) /gene="yqjT" /locus_tag="BSU_23750" /old_locus_tag="BSU23750" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative lyase" /protein_id="NP_390256.1" /db_xref="EnsemblGenomes-Gn:BSU23750" /db_xref="EnsemblGenomes-Tr:CAB14307" /db_xref="InterPro:IPR029068" /db_xref="SubtiList:BG11749" /db_xref="UniProtKB/Swiss-Prot:P54557" /translation="MHHIELYVSDLEASRRFWGWFLKELGYKEYQKWSSGISWKKDRF YLVIVQAKEPFLEPEYHRCRVGLNHLAFHAESKLQVDQMTEKLTAKGYRVLYRDRHPF AGGDGHYAVFCEDPDRIKVELVAPSC*" gene complement(2333757..2334143) /gene="yqjT" /locus_tag="BSU_23750" /old_locus_tag="BSU23750" CDS complement(2334147..2335106) /gene="coaA" /locus_tag="BSU_23760" /old_locus_tag="BSU23760" /EC_number="2.7.1.33" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:1328157, 24784177" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1328157, 24784177; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="pantothenate kinase" /protein_id="NP_390257.2" /db_xref="EnsemblGenomes-Gn:BSU23760" /db_xref="EnsemblGenomes-Tr:CAB14308" /db_xref="GOA:P54556" /db_xref="InterPro:IPR004566" /db_xref="InterPro:IPR006083" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG11748" /db_xref="UniProtKB/Swiss-Prot:P54556" /translation="MKNKELNLHTLYTQHNRESWSGFGGHLSIAVSEEEAKAVEGLND YLSVEEVETIYIPLVRLLHLHVKSAAERNKHVNVFLKHPHSAKIPFIIGIAGSVAVGK STTARILQKLLSRLPDRPKVSLITTDGFLFPTAELKKKNMMSRKGFPESYDVKALLEF LNDLKSGKDSVKAPVYSHLTYDREEGVFEVVEQADIVIIEGINVLQSPTLEDDRENPR IFVSDFFDFSIYVDAEESRIFTWYLERFRLLRETAFQNPDSYFHKFKDLSDQEADEMA ASIWESVNRPNLYENILPTKFRSDLILRKGDGHKVEEVLVRRV*" gene complement(2334147..2335106) /gene="coaA" /locus_tag="BSU_23760" /old_locus_tag="BSU23760" S_feature complement(2335107..2335177) /Source="Nicolas_S_feature" /locus_tag="new_2469509_2469579_c" /HighExp="LBGtran, dia15, Diami, C90, H2O2, M0t45, G135, Lbtran, HiTm, G150" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S900" CDS complement(2335178..2336524) /gene="dsdA" /locus_tag="BSU_23770" /old_locus_tag="BSU23770" /EC_number="4.3.1.18" /function="16.8: Protect" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 7592420; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="D-serine ammonia-lyase" /protein_id="NP_390258.2" /db_xref="EnsemblGenomes-Gn:BSU23770" /db_xref="EnsemblGenomes-Tr:CAB14309" /db_xref="GOA:P54555" /db_xref="InterPro:IPR000634" /db_xref="InterPro:IPR001926" /db_xref="InterPro:IPR011780" /db_xref="InterPro:IPR036052" /db_xref="SubtiList:BG11747" /db_xref="UniProtKB/Swiss-Prot:P54555" /translation="MSVHSEVLHALLKDPFIQKLIDAEPVFWANSGKKEGPLPRADEW ATEIAEAEKRMQRFAPYIAEVFPETKGAKGIIESPLFEVQHMKGKLEAAYQQPFPGRW LLKCDHELPISGSIKARGGIYEVLKYAENLALQEGMLQETDDYRILQEERFTGFFSRY SIAVGSTGNLGLSIGIIGAALGFRVTVHMSADAKQWKKDLLRQKGVTVMEYETDYSEA VNEGRRQAEQDPFCYFIDDEHSRQLFLGYAVAASRLKTQLDCMNIKPSLETPLFVYLP CGVGGGPGGVAFGLKLLYGDDVHVFFAEPTHSPCMLLGLYSGLHEKISVQDIGLDNQT AADGLAVGRPSGFVGKLIEPLLSGCYTVEDNTLYTLLHMLAVSEDKYLEPSALAGMFG PVQLFSTEEGRRYAQKYKMEHAVHVVWGTGGSMVPKDEMAAYNRIGADLLKKRNEK*" gene complement(2335178..2336524) /gene="dsdA" /locus_tag="BSU_23770" /old_locus_tag="BSU23770" S_feature complement(2336525..2336599) /Source="Nicolas_S_feature" /locus_tag="new_2470927_2471001_c" /HighExp="C90, LBGtran, Diami, dia15, H2O2, dia5, G150, MG 15, GM-0.2, M40t45" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S901" CDS complement(2336600..2337379) /gene="yqjQ" /locus_tag="BSU_23780" /old_locus_tag="BSU23780" /EC_number="1.1.1.-" /function="16.11: Scavenge (Catabolism)" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative metabolite dehydrogenase, NAD-binding" /protein_id="NP_390259.1" /db_xref="EnsemblGenomes-Gn:BSU23780" /db_xref="EnsemblGenomes-Tr:CAB14310" /db_xref="GOA:P54554" /db_xref="InterPro:IPR002347" /db_xref="InterPro:IPR020904" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG11746" /db_xref="UniProtKB/Swiss-Prot:P54554" /translation="MKHIAGKRIWITGASGGLGERIAYLCAAEGAHVLLSARREDRLI EIKRKITEEWSGQCEIFPLDVGRLEDIARVRDQIGSIDVLINNAGFGIFETVLDSTLD DMKAMFDVNVFGLIACTKAVLPQMLEQKKGHIINIASQAGKIATPKSSLYSATKHAVL GYSNALRMELSGTGIYVTTVNPGPIQTDFFSIADKGGDYAKNVGRWMLDPDDVAAQIT AAIFTKKREINLPRLMNAGTKLYQLFPALVEKLAGRALMKK*" gene complement(2336600..2337379) /gene="yqjQ" /locus_tag="BSU_23780" /old_locus_tag="BSU23780" CDS complement(2337385..2338344) /gene="yqjP" /locus_tag="BSU_23790" /old_locus_tag="BSU23790" /EC_number="3.-.-.-" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative metal-dependent hydrolase" /protein_id="NP_390260.1" /db_xref="EnsemblGenomes-Gn:BSU23790" /db_xref="EnsemblGenomes-Tr:CAB14311" /db_xref="GOA:P54553" /db_xref="InterPro:IPR001279" /db_xref="InterPro:IPR036866" /db_xref="SubtiList:BG11745" /db_xref="UniProtKB/Swiss-Prot:P54553" /translation="MTTEDVIAIRVPTPFAVGDVIVYLVKGDALTLIDAGPNTKEAAR ALQEQLAAVNVKLSDIEQVVLTHHHADHAGLLDVFSDEIEVIGHTFNEPYISQNQAFM DWQKRFFQKLLPELGVPFDTGKAEKLIRSAYAFSCTRSLTKSIREGMGIDGLEGWSVL EMPGHAESHIVLFHEKSGRMLGGDLLLANSSSNPILEAPKAGDVRSKPLVDYQRSLRR LSQLDPTIVFPGHGEPITSVQALIEKRFDKQRNRTEDVRRMLDEKPMTAFQVCQQLFP AVYEKELFLTMSETAGHLDVLEAEEAITSYWEGNTVYFKTMKR*" gene complement(2337385..2338344) /gene="yqjP" /locus_tag="BSU_23790" /old_locus_tag="BSU23790" promotor_-10 complement(2338366..2338385) /Source="Nicolas_upshift_promotors" /id="U1858" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.597402597402597" /psig=1 /xcortree=2254 /SigmaFactorBS="caatagctttttcaaaaaggtttgttctcattctgcaaTAAT GACAcaagaccgagaaaaAGCTAAAATATGAATAATGAatgaagacaaggagcgaaag g" /listShort="yqjP, yqjQ, S901, dsdA, S900, coaA, yqjT, S899" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2338385) /Source="Nicolas_upshifts" /id="U1858" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.597402597402597" /psig=1 /xcortree=2254 /SigmaFactorBS="caatagctttttcaaaaaggtttgttctcattctgcaaTAAT GACAcaagaccgagaaaaAGCTAAAATATGAATAATGAatgaagacaaggagcgaaag g" /listShort="yqjP, yqjQ, S901, dsdA, S900, coaA, yqjT, S899" /GFF_Attribute="listLong" promotor_-35 complement(2338400..2338407) /Source="Nicolas_upshift_promotors" /id="U1858" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.597402597402597" /psig=1 /xcortree=2254 /SigmaFactorBS="caatagctttttcaaaaaggtttgttctcattctgcaaTAAT GACAcaagaccgagaaaaAGCTAAAATATGAATAATGAatgaagacaaggagcgaaag g" /listShort="yqjP, yqjQ, S901, dsdA, S900, coaA, yqjT, S899" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 2338441..2338448 /Source="Nicolas_upshift_promotors" /id="U1859" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.784215784215784" /psig="0.992007992007992" /xcortree=573 /SigmaFactorBS="tcattattgcagaatgagaacaaacctttttgaaaaagcTAT TGACAttagcttgtccgccaTTGCATAATGAACAACAAACtaaaacgagaaccattgg a" /listShort="S902, proI" /GFF_Attribute="listLong" /label="promotor_-35" S_feature 2338462..2338748 /Source="Nicolas_S_feature" /locus_tag="new_2472864_2473150" /HighExp="Diami, C90, BC, Paraq, G180, GM 15, Oxctl, S7, MG-0.2, MG t5" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.992" /TUlongSig="NA" /TUlongPSig="NA" /label="S902" upshifts 2338462 /Source="Nicolas_upshifts" /id="U1859" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.784215784215784" /psig="0.992007992007992" /xcortree=573 /SigmaFactorBS="tcattattgcagaatgagaacaaacctttttgaaaaagcTAT TGACAttagcttgtccgccaTTGCATAATGAACAACAAACtaaaacgagaaccattgg a" /listShort="S902, proI" /GFF_Attribute="listLong" promotor_-10 2338464..2338483 /Source="Nicolas_upshift_promotors" /id="U1859" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.784215784215784" /psig="0.992007992007992" /xcortree=573 /SigmaFactorBS="tcattattgcagaatgagaacaaacctttttgaaaaagcTAT TGACAttagcttgtccgccaTTGCATAATGAACAACAAACtaaaacgagaaccattgg a" /listShort="S902, proI" /GFF_Attribute="listLong" /label="promotor_-10" misc_RNA 2338478..2338723 /gene="pswI" /locus_tag="BSU_misc_RNA_91" /product="proline T-box riboswitch" /experiment="publication(s) with functional evidences, PMID:21233158" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 21233158" gene 2338478..2338723 /gene="pswI" /locus_tag="BSU_misc_RNA_91" CDS 2338749..2339585 /gene="proI" /locus_tag="BSU_23800" /old_locus_tag="BSU23800" /EC_number="1.5.1.2" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:11418582, 21233158, 28752945, 28824574" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11418582, 21233158, 28752945, 28824574; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="pyrroline-5-carboxylate reductase (NADP-dependent, weak activity)" /protein_id="NP_390261.1" /db_xref="EnsemblGenomes-Gn:BSU23800" /db_xref="EnsemblGenomes-Tr:CAB14312" /db_xref="GOA:P54552" /db_xref="InterPro:IPR000304" /db_xref="InterPro:IPR008927" /db_xref="InterPro:IPR028939" /db_xref="InterPro:IPR029036" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG11744" /db_xref="UniProtKB/Swiss-Prot:P54552" /translation="MKKIGFVGAGSMAEAMINGILQSGITKPEHIYITNRSNDERLIE LKETYSVRPCRDKNEFFTHTDIIILAFKPKDAAESIDSIRPYIKDQLVISVLAGLTIE TIQHYFGRKLAVIRVMPNTSAAIRKSATGFSVSTEASKNDIIAAKALLETIGDATLVE ERHLDAVTAIAGSGPAYVYRYIEAMEKAAQKVGLDKETAKALILQTMAGATDMLLQSG KQPEKLRKEITSPGGTTEAGLRALQDSRFEEAIIHCIEETAKRSAEIKEQFAGAALER HS*" gene 2338749..2339585 /gene="proI" /locus_tag="BSU_23800" /old_locus_tag="BSU23800" downshifts 2339583 /Source="Nicolas_upshifts" /id="D1238" /incds=0 /nref=29 /ntot=190 /MaxReadThrough="0.55696" /MaxDrop="3.78131" /score="36.2472665" /energy="-12" /TU="NA" /idTUdmin="U1859" /TUdmin="-1" /isTUend="TRUE" CDS complement(2339626..2341269) /gene="yqjN" /locus_tag="BSU_23810" /old_locus_tag="BSU23810" /function="16.8: Protect" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative N-deacylase" /protein_id="NP_390262.2" /db_xref="EnsemblGenomes-Gn:BSU23810" /db_xref="EnsemblGenomes-Tr:CAB14313" /db_xref="GOA:P54551" /db_xref="InterPro:IPR002933" /db_xref="InterPro:IPR012166" /db_xref="SubtiList:BG11743" /db_xref="UniProtKB/Swiss-Prot:P54551" /translation="MNWQTKDELLALLTSLVQYESITGSKGEVALAEYLYFILKDKPY FQKHPDDVTLHPMDDGRSFLTALVKKKNVKKTVLLLSHFDVVDIEDYGEFKHMACKPA ELLSSFLEKKELLPERVRRDAESGDWLFGRGTMDMKAGLCIQLSMLERAMNGHFEGNL LLITVPDEEVNSRGMIEAVPALKEMEKKHDITLTACLNAEPMFEKFPGDQQQYFYTGS IGKVLAGFFCKGIETHVGEPFSGLNANLMVSEINRLLELNADYCEKVDGEVTPPPVNL MQKDLKEAYSVQTPHTAVTLFNVLSMKRSASELHQMLLKTAEQAAEEIMSNVRKKTQD FQQFEPFQPIERDVTVLTFDELVSRAKKRAGISETERALNYAFANRGELGDRDFSTKI VSELASLCKEDAPLIVLFYSPPLYPAVSSKDDQLIRNTADQIKHYAAERYGIALREVQ YFPGLSDLSYLQLEKQEVDAYTSNMPLFNRGYSLPSGKNQALYVPVLNVGPAGKDPHK WTERLYMPYSFEVLPDLLSFTISALLKQSESAGQLLREK*" gene complement(2339626..2341269) /gene="yqjN" /locus_tag="BSU_23810" /old_locus_tag="BSU23810" downshifts complement(2339638) /Source="Nicolas_upshifts" /id="D1239" /incds=0 /nref=1 /ntot=62 /MaxReadThrough="2.2598" /MaxDrop="2.55609" /score="14.9380989" /energy="-12" /TU="NA" /idTUdmin="U1861" /TUdmin=0 /isTUend="TRUE" promotor_-35 2341287..2341293 /Source="Nicolas_upshift_promotors" /id="U1860" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.94105894105894" /psig="0.94105894105894" /xcortree=822 /SigmaFactorBS="cagcaattcgtccttcgtctgccaattcattgattccgcccc tcctaTGAATAAaaatgcttctataCTGAAAAATAAActgatttctcgtctattatac a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 2341300 /Source="Nicolas_upshifts" /id="U1860" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.94105894105894" /psig="0.94105894105894" /xcortree=822 /SigmaFactorBS="cagcaattcgtccttcgtctgccaattcattgattccgcccc tcctaTGAATAAaaatgcttctataCTGAAAAATAAActgatttctcgtctattatac a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 2341307..2341318 /Source="Nicolas_upshift_promotors" /id="U1860" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.94105894105894" /psig="0.94105894105894" /xcortree=822 /SigmaFactorBS="cagcaattcgtccttcgtctgccaattcattgattccgcccc tcctaTGAATAAaaatgcttctataCTGAAAAATAAActgatttctcgtctattatac a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" misc_feature complement(2341325..2341344) /Source="Nicolas_upshift_promotors" /id="U1861" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.976023976023976" /psig="0.999000999001" /xcortree=397 /SigmaFactorBS="ctttcccgtcatataaactgctcaaatgaaccgcttttgtca aacaTTTCTGTATAATAGACGAGAaatcagtttatttttcagtatagaagcattttta t" /listShort="yqjN" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(2341330) /Source="Nicolas_upshifts" /id="U1861" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.976023976023976" /psig="0.999000999001" /xcortree=397 /SigmaFactorBS="ctttcccgtcatataaactgctcaaatgaaccgcttttgtca aacaTTTCTGTATAATAGACGAGAaatcagtttatttttcagtatagaagcattttta t" /listShort="yqjN" /GFF_Attribute="listLong" promotor_-35 2341376..2341383 /Source="Nicolas_upshift_promotors" /id="U1862" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.681318681318681" /psig="0.999000999001" /xcortree=1795 /SigmaFactorBS="cagaaatgtttgacaaaagcggttcatttgagcagttTATAT GACgggaaagaaatgaCTTGATATAATCAATCTCTAaaaaccttacgggaggcgaaag a" /listShort="yqjM, yqjL" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2341397..2341416 /Source="Nicolas_upshift_promotors" /id="U1862" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.681318681318681" /psig="0.999000999001" /xcortree=1795 /SigmaFactorBS="cagaaatgtttgacaaaagcggttcatttgagcagttTATAT GACgggaaagaaatgaCTTGATATAATCAATCTCTAaaaaccttacgggaggcgaaag a" /listShort="yqjM, yqjL" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2341399 /Source="Nicolas_upshifts" /id="U1862" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.681318681318681" /psig="0.999000999001" /xcortree=1795 /SigmaFactorBS="cagaaatgtttgacaaaagcggttcatttgagcagttTATAT GACgggaaagaaatgaCTTGATATAATCAATCTCTAaaaaccttacgggaggcgaaag a" /listShort="yqjM, yqjL" /GFF_Attribute="listLong" CDS 2341441..2342457 /gene="yqjM" /locus_tag="BSU_23820" /old_locus_tag="BSU23820" /EC_number="1.6.99.1" /function="16.8: Protect" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:12660247, 15249051, 15890652, 20011599, 20461254" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12660247, 15249051, 15890652, 20011599, 20461254; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="NADPH-dependent flavin oxidoreductase (acting oncinnamaldehyde-related compounds)" /protein_id="NP_390263.1" /db_xref="EnsemblGenomes-Gn:BSU23820" /db_xref="EnsemblGenomes-Tr:CAB14314" /db_xref="GOA:P54550" /db_xref="InterPro:IPR001155" /db_xref="InterPro:IPR013785" /db_xref="InterPro:IPR023663" /db_xref="PDB:1Z41" /db_xref="PDB:1Z42" /db_xref="PDB:1Z44" /db_xref="PDB:1Z48" /db_xref="SubtiList:BG11742" /db_xref="UniProtKB/Swiss-Prot:P54550" /translation="MARKLFTPITIKDMTLKNRIVMSPMCMYSSHEKDGKLTPFHMAH YISRAIGQVGLIIVEASAVNPQGRITDQDLGIWSDEHIEGFAKLTEQVKEQGSKIGIQ LAHAGRKAELEGDIFAPSAIAFDEQSATPVEMSAEKVKETVQEFKQAAARAKEAGFDV IEIHAAHGYLIHEFLSPLSNHRTDEYGGSPENRYRFLREIIDEVKQVWDGPLFVRVSA SDYTDKGLDIADHIGFAKWMKEQGVDLIDCSSGALVHADINVFPGYQVSFAEKIREQA DMATGAVGMITDGSMAEEILQNGRADLIFIGRELLRDPFFARTAAKQLNTEIPAPVQY ERGW*" gene 2341441..2342457 /gene="yqjM" /locus_tag="BSU_23820" /old_locus_tag="BSU23820" downshifts 2342444 /Source="Nicolas_upshifts" /id="D1240" /incds=0 /nref=42 /ntot=157 /MaxReadThrough="2.79686" /MaxDrop="5.04803" /score="39.119339" /energy="-12.8" /TU="U1862" /idTUdmin="U1862" /TUdmin="-770" /isTUend="FALSE" promotor_-35 2342506..2342515 /Source="Nicolas_upshift_promotors" /id="U1863" /multdbtbs="SigW,SigX" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1646 /SigmaFactorBS="atcctgtagaggatatctctttttttatttttagAGAAACGA TCggctaaggttctCCGTCTCCCTAGTAGAaccaattagaggagatgactccaatgaa a" /listShort="yqjL" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2342528..2342543 /Source="Nicolas_upshift_promotors" /id="U1863" /multdbtbs="SigW,SigX" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1646 /SigmaFactorBS="atcctgtagaggatatctctttttttatttttagAGAAACGA TCggctaaggttctCCGTCTCCCTAGTAGAaccaattagaggagatgactccaatgaa a" /listShort="yqjL" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2342532 /Source="Nicolas_upshifts" /id="U1863" /multdbtbs="SigW,SigX" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1646 /SigmaFactorBS="atcctgtagaggatatctctttttttatttttagAGAAACGA TCggctaaggttctCCGTCTCCCTAGTAGAaccaattagaggagatgactccaatgaa a" /listShort="yqjL" /GFF_Attribute="listLong" CDS 2342567..2343328 /gene="yqjL" /locus_tag="BSU_23830" /old_locus_tag="BSU23830" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15838020, 22720735; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative hydrolase" /protein_id="NP_390264.1" /db_xref="EnsemblGenomes-Gn:BSU23830" /db_xref="EnsemblGenomes-Tr:CAB14315" /db_xref="InterPro:IPR022742" /db_xref="InterPro:IPR029058" /db_xref="SubtiList:BG11741" /db_xref="UniProtKB/Swiss-Prot:P54549" /translation="MKSAWMEKTYTIDGCAFHTQHRKGSSGVTIVFEAGYGTSSETWK PLMADIDDEFGIFTYDRAGIGKSGQSRAKRTADQQVKELESLLKAADVKPPYLAVSHS YGAVITGLWACKNKHDIIGMVLLDPALGDCASFTFIPEEMHKSHTRKMMLEGTHAEFS KSLQELKKRQVHLGNMPLLVLSSGERTEKFAAEQEWQNLHSSILSLSNQSGWIQAKNS SHNIHHDEPHIVHLAIYDVWCAACQQAAPLYQAVN*" gene 2342567..2343328 /gene="yqjL" /locus_tag="BSU_23830" /old_locus_tag="BSU23830" downshifts 2343236 /Source="Nicolas_upshifts" /id="D1241" /incds=1 /nref=21 /ntot=204 /MaxReadThrough="3.34804" /MaxDrop="3.21955" /score="0.451826768" /energy="-11.2" /TU="U1863" /idTUdmin="U1862" /TUdmin=22 /isTUend="TRUE" downshifts 2343324 /Source="Nicolas_upshifts" /id="D1242" /incds=0 /nref=4 /ntot=33 /MaxReadThrough="1.34151" /MaxDrop="3.85711" /score="0.451826768" /energy="-11.2" /TU="NA" /idTUdmin="U1863" /TUdmin=0 /isTUend="TRUE" S_feature complement(2343356..2343556) /Source="Nicolas_S_feature" /locus_tag="new_2477758_2477958_c" /HighExp="B60, S5, Etha, S4, B36, BMM, Heat, S3, S2, S6" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.21631400000000001" /TUshortSig="SigA, SigA" /TUshortPSig="1, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S903" CDS complement(2343372..2343497) /gene="rpmGCc" /locus_tag="BSU_23836" /old_locus_tag="BSU23836" /function="10.2: Ribosomal proteins: synthesis and modification" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function; PubMedId : 27561249; Product type s: structure" /pseudo /codon_start=1 /transl_table=11 /product="ribosomal protein L33* pseudogene" /translation="CTETGDRNYITTKNKRTNPDRLELKKYSPRLKKYTLHRETK*" gene complement(2343372..2343497) /gene="rpmGCc" /locus_tag="BSU_23836" /old_locus_tag="BSU23836" /pseudo downshifts complement(2343399) /Source="Nicolas_upshifts" /id="D1243" /incds=0 /nref=187 /ntot=264 /MaxReadThrough="3.91531" /MaxDrop="7.65732" /score="5.23287853" /energy="-8.8" /TU="U1864" /idTUdmin="U1865" /TUdmin=1 /isTUend="TRUE" CDS complement(2343490..2343522) /gene="rpmGCn" /locus_tag="BSU_23837" /old_locus_tag="BSU23837" /function="10.2: Ribosomal proteins: synthesis and modification" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function; PubMedId : 19648245, 27561249; Product type s: structure" /pseudo /codon_start=1 /transl_table=11 /product="ribosomal protein L33C pseudogene" /db_xref="PSEUDO:CCQ48601.1" /translation="MRVNVTLALH*" gene complement(2343490..2343522) /gene="rpmGCn" /locus_tag="BSU_23837" /old_locus_tag="BSU23837" /pseudo promotor_-10 complement(2343550..2343569) /Source="Nicolas_upshift_promotors" /id="U1864" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.597402597402597" /psig=1 /xcortree=665 /SigmaFactorBS="cccgcgaggctgaaggcggagctcttaTTTGACAAtttgtga tgacgTTGTATAATAAAACGTAATCattacgttttataaggagatgttaattatgaga g" /listShort="S903" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2343556) /Source="Nicolas_upshifts" /id="U1864" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.597402597402597" /psig=1 /xcortree=665 /SigmaFactorBS="cccgcgaggctgaaggcggagctcttaTTTGACAAtttgtga tgacgTTGTATAATAAAACGTAATCattacgttttataaggagatgttaattatgaga g" /listShort="S903" /GFF_Attribute="listLong" promotor_-35 complement(2343582..2343589) /Source="Nicolas_upshift_promotors" /id="U1864" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.597402597402597" /psig=1 /xcortree=665 /SigmaFactorBS="cccgcgaggctgaaggcggagctcttaTTTGACAAtttgtga tgacgTTGTATAATAAAACGTAATCattacgttttataaggagatgttaattatgaga g" /listShort="S903" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2343604..2344527) /gene="rnz" /locus_tag="BSU_23840" /old_locus_tag="BSU23840" /EC_number="3.1.26.11" /function="16.2: Construct biomass (Anabolism)" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:12682299, 12941704, 16336119, 17005971" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12682299, 12941704, 16336119, 17005971; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="ribonuclease Z" /protein_id="NP_390265.1" /db_xref="EnsemblGenomes-Gn:BSU23840" /db_xref="EnsemblGenomes-Tr:CAB14316" /db_xref="GOA:P54548" /db_xref="InterPro:IPR001279" /db_xref="InterPro:IPR013471" /db_xref="InterPro:IPR036866" /db_xref="PDB:1Y44" /db_xref="PDB:2FK6" /db_xref="PDB:4GCW" /db_xref="SubtiList:BG11740" /db_xref="UniProtKB/Swiss-Prot:P54548" /translation="MELLFLGTGAGIPAKARNVTSVALKLLEERRSVWLFDCGEATQH QILHTTIKPRKIEKIFITHMHGDHVYGLPGLLGSRSFQGGEDELTVYGPKGIKAFIET SLAVTKTHLTYPLAIQEIEEGIVFEDDQFIVTAVSVIHGVEAFGYRVQEKDVPGSLKA DVLKEMNIPPGPVYQKIKKGETVTLEDGRIINGNDFLEPPKKGRSVVFSGDTRVSDKL KELARDCDVLVHEATFAKEDRKLAYDYYHSTTEQAAVTAKEARAKQLILTHISARYQG DASLELQKEAVDVFPNSVAAYDFLEVNVPRG*" gene complement(2343604..2344527) /gene="rnz" /locus_tag="BSU_23840" /old_locus_tag="BSU23840" promotor_-10 complement(2344553..2344572) /Source="Nicolas_upshift_promotors" /id="U1865" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.492507492507492" /psig=1 /xcortree=2380 /SigmaFactorBS="tctagcacgaaaggattgttcttttcagaggcaagATTCACa ttttccgcttgaTCCTGTATTCTTGTAGGTATctggttctagtaggaggaaggaaacg t" /listShort="rnz, S903" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2344566) /Source="Nicolas_upshifts" /id="U1865" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.492507492507492" /psig=1 /xcortree=2380 /SigmaFactorBS="tctagcacgaaaggattgttcttttcagaggcaagATTCACa ttttccgcttgaTCCTGTATTCTTGTAGGTATctggttctagtaggaggaaggaaacg t" /listShort="rnz, S903" /GFF_Attribute="listLong" promotor_-35 complement(2344586..2344591) /Source="Nicolas_upshift_promotors" /id="U1865" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.492507492507492" /psig=1 /xcortree=2380 /SigmaFactorBS="tctagcacgaaaggattgttcttttcagaggcaagATTCACa ttttccgcttgaTCCTGTATTCTTGTAGGTATctggttctagtaggaggaaggaaacg t" /listShort="rnz, S903" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 2344665..2344672 /Source="Nicolas_upshift_promotors" /id="U1866" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.676323676323676" /psig=1 /xcortree=2347 /SigmaFactorBS="acattttttcagcattctgcttaaaaaagggcttaaaTGTTT GCTttcgttgaattttAGATTTAAAATGAAGGAAATatacggggtgtactaaaataaa g" /listShort="S904, zwf" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2344686..2344705 /Source="Nicolas_upshift_promotors" /id="U1866" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.676323676323676" /psig=1 /xcortree=2347 /SigmaFactorBS="acattttttcagcattctgcttaaaaaagggcttaaaTGTTT GCTttcgttgaattttAGATTTAAAATGAAGGAAATatacggggtgtactaaaataaa g" /listShort="S904, zwf" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 2344688..2344753 /Source="Nicolas_S_feature" /locus_tag="new_2479090_2479155" /HighExp="dia5, C90, MG 5, Lbexp, MG t5, MG 45, M9-exp, GM 90, GM 120, GM-0.2" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S904" upshifts 2344688 /Source="Nicolas_upshifts" /id="U1866" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.676323676323676" /psig=1 /xcortree=2347 /SigmaFactorBS="acattttttcagcattctgcttaaaaaagggcttaaaTGTTT GCTttcgttgaattttAGATTTAAAATGAAGGAAATatacggggtgtactaaaataaa g" /listShort="S904, zwf" /GFF_Attribute="listLong" CDS 2344754..2346223 /gene="zwf" /locus_tag="BSU_23850" /old_locus_tag="BSU23850" /EC_number="1.1.1.49" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:1704005, 19779711, 26129872" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1704005, 19779711, 26129872; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="glucose-6-phosphate 1-dehydrogenase (NADP-dependent)" /protein_id="NP_390266.2" /db_xref="EnsemblGenomes-Gn:BSU23850" /db_xref="EnsemblGenomes-Tr:CAB14317" /db_xref="GOA:P54547" /db_xref="InterPro:IPR001282" /db_xref="InterPro:IPR019796" /db_xref="InterPro:IPR022674" /db_xref="InterPro:IPR022675" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG11739" /db_xref="UniProtKB/Swiss-Prot:P54547" /translation="MKTNQQPKAVIVIFGATGDLAKRKLYPSIHRLYQNGQIGEEFAV VGVGRRPWSNEDLRQTVKTSISSSADKHIDDFTSHFYYHPFDVTNPGSYQELNVLLNQ LEDTYQIPNNRMFYLAMAPEFFGTIAKTLKSEGVTATTGWSRLVIEKPFGHDLPSAQA LNKEIREAFTEDQIYRIDHYLGKQMVQNIEVIRFANAIFEPLWTNRYISNIQITSSES LGVEDRARYYEKSGALRDMVQNHIMQMVALLAMEPPIKLNTEEIRSEKVKVLRALRPI AKDEVDEYFVRGQYHAGEIDGVPVPAYTDEDNVAPDSNTETFVAGKLLIDNFRWAGVP FYIRTGKRMKEKSTKIVVQFKDIPMNLYYGNENNMNPNLLVIHIQPDEGITLYLNAKK LGGAAHAQPIKLDYCSNCNDELNTPEAYEKLIHDCLLGDATNFAHWDEVALSWSFVDS ISETWAANKTLSPNYESGSMGPKESDDLLVKDGLHWWNI*" gene 2344754..2346223 /gene="zwf" /locus_tag="BSU_23850" /old_locus_tag="BSU23850" downshifts 2346206 /Source="Nicolas_upshifts" /id="D1244" /incds=0 /nref=206 /ntot=286 /MaxReadThrough="3.46838" /MaxDrop="7.76173" /score="1.1363172" /energy="-15.2" /TU="U1866" /idTUdmin="U1866" /TUdmin="-90" /isTUend="FALSE" downshifts 2346274 /Source="Nicolas_upshifts" /id="D1245" /incds=0 /nref=1 /ntot=104 /MaxReadThrough="2.5392" /MaxDrop="4.74183" /score="1.1363172" /energy="-15.2" /TU="U1866" /idTUdmin="U1866" /TUdmin="-22" /isTUend="TRUE" CDS complement(2346348..2347757) /gene="gndA" /locus_tag="BSU_23860" /old_locus_tag="BSU23860" /EC_number="1.1.1.44" /function="16.2: Construct biomass (Anabolism)" /function="16.7: Manage energy" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:15231785, 15755726" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15231785, 15755726; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="NADP+-dependent 6-P-gluconate dehydrogenase" /protein_id="NP_390267.2" /db_xref="EnsemblGenomes-Gn:BSU23860" /db_xref="EnsemblGenomes-Tr:CAB14318" /db_xref="GOA:P80859" /db_xref="InterPro:IPR006113" /db_xref="InterPro:IPR006114" /db_xref="InterPro:IPR006115" /db_xref="InterPro:IPR006183" /db_xref="InterPro:IPR006184" /db_xref="InterPro:IPR008927" /db_xref="InterPro:IPR013328" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG11738" /db_xref="UniProtKB/Swiss-Prot:P80859" /translation="MSKQQIGVIGLAVMGKNLALNIESRGFSVSVYNRSSSKTEEFLQ EAKGKNVVGTYSIEEFVQSLETPRKILLMVKAGTATDATIQSLLPHLEKDDILIDGGN TYYKDTQRRNKELAESGIHFIGTGVSGGEEGALKGPSIMPGGQKEAHELVKPILEAIS AKVDGEPCTTYIGPDGAGHYVKMVHNGIEYGDMQLISESYFILKQVLGLSADELHEVF AEWNKGELDSYLIEITADIFTKKDEETGKPLVDVILDKAGQKGTGKWTSQSALDLGVP LPIITESVFARFISAMKEERVKASGLLSGPEVKPVTENKEELIEAVRKALFMSKICSY AQGFAQMKAASEEYNWDLKYGEIAMIFRGGCIIRAAFLQKIKEAYDREPELDNLLLDS YFKNIVESYQGALRQVISLAVAQGVPVPSFSSALAYYDSYRTAVLPANLIQAQRDYFG AHTYERTDKEGIFHTEWMK*" gene complement(2346348..2347757) /gene="gndA" /locus_tag="BSU_23860" /old_locus_tag="BSU23860" downshifts complement(2346365) /Source="Nicolas_upshifts" /id="D1246" /incds=0 /nref=220 /ntot=361 /MaxReadThrough="1.88983" /MaxDrop="8.82894" /score="24.3727084" /energy="-18" /TU="NA" /idTUdmin="U1867" /TUdmin="-15" /isTUend="TRUE" downshifts complement(2346438) /Source="Nicolas_upshifts" /id="D1247" /incds=1 /nref=1 /ntot=36 /MaxReadThrough="8.40595" /MaxDrop="2.3555" /score="24.3727084" /energy="-18" /TU="U1867" /idTUdmin="U1867" /TUdmin="-88" /isTUend="FALSE" misc_feature complement(2347821..2347839) /Source="Nicolas_upshift_promotors" /id="U1867" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.377622377622378" /psig="0.987012987012987" /xcortree=2358 /SigmaFactorBS="atgaaaagaaaagctgaatcgcttgaaaaaaagggtgaatgt atGGTAATTTCTTTATTATAAatatcattttattttaatttaaattttaaaatgatta a" /listShort="gndA" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(2347823) /Source="Nicolas_upshifts" /id="U1867" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.377622377622378" /psig="0.987012987012987" /xcortree=2358 /SigmaFactorBS="atgaaaagaaaagctgaatcgcttgaaaaaaagggtgaatgt atGGTAATTTCTTTATTATAAatatcattttattttaatttaaattttaaaatgatta a" /listShort="gndA" /GFF_Attribute="listLong" CDS complement(2347867..2349111) /gene="polYA" /locus_tag="BSU_23870" /old_locus_tag="BSU23870" /EC_number="2.7.7.7" /function="16.6: Maintain" /function="16.5: Explore" /function="16.9: Replicate" /experiment="publication(s) with functional evidences, PMID:12137951, 12644484, 15469515, 16045613, 25713353" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12137951, 12644484, 15469515, 16045613, 25713353; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="DNA-damage lesion bypass DNA polymerase" /protein_id="NP_390268.2" /db_xref="EnsemblGenomes-Gn:BSU23870" /db_xref="EnsemblGenomes-Tr:CAB14319" /db_xref="GOA:P54545" /db_xref="InterPro:IPR001126" /db_xref="InterPro:IPR017061" /db_xref="InterPro:IPR017961" /db_xref="InterPro:IPR022880" /db_xref="InterPro:IPR024728" /db_xref="InterPro:IPR036775" /db_xref="SubtiList:BG11737" /db_xref="UniProtKB/Swiss-Prot:P54545" /translation="MPGKSRIIFHIDMNSFYASVEMAYDPALRGKPVAVAGNVKERKG IVVTCSYEARARGVKTTMPVWQAKRHCPELIVLPPNFDRYRNSSRAMFTILREYTDLV EPVSIDEGYMDMTDTPYSSRALETAKEIQSRLQKELLLPSSIGIAPNKFLAKMASDMK KPLGITILRKRQVPDILWPLPVGEMHGVGKKTAEKLKGLGIHTIGELAAADEHSLKRL LGINGPRLKNKANGIHHAPVDPERIYEFKSVGNSSTLSHDSSDEEELLGVFRKLAASV SDRLQRKEVMASKLFIMIRYADWRTITRSTTLRNPIDQKNDILKEAEHLFFKHWNKNP VRLLGITGTDLVEKEQAYKQLDLFSFNEDAKDEPIQQMMEKLNKKYGTKLIRKGATLK KEESKTKGTSFNKDFFQDEKKS*" gene complement(2347867..2349111) /gene="polYA" /locus_tag="BSU_23870" /old_locus_tag="BSU23870" S_feature complement(2349112..2349386) /Source="Nicolas_S_feature" /locus_tag="new_2483514_2483788_c" /HighExp="M40t90, Sw, M40t45, H2O2, C30, Cold, Etha, C90, Diami, BC" /AntisenseName="yqzJ" /AntisenseCor="0.48883700687558601" /AntisenseRegPval="-16.8" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.993" /TUlongSig="NA" /TUlongPSig="NA" /label="S905" promotor_-35 2349132..2349139 /Source="Nicolas_upshift_promotors" /id="U1868" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.635364635364635" /psig="0.994005994005994" /xcortree=2144 /SigmaFactorBS="ttcggctctttcccggcataaacaaatctccttttcggtCAT TAGACaacagcttgtacaTATAGTAAAATGAAGCTATTgaatggatgtgatgacaatg t" /listShort="yqzJ, oxaAB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2349153..2349172 /Source="Nicolas_upshift_promotors" /id="U1868" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.635364635364635" /psig="0.994005994005994" /xcortree=2144 /SigmaFactorBS="ttcggctctttcccggcataaacaaatctccttttcggtCAT TAGACaacagcttgtacaTATAGTAAAATGAAGCTATTgaatggatgtgatgacaatg t" /listShort="yqzJ, oxaAB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2349153 /Source="Nicolas_upshifts" /id="U1868" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.635364635364635" /psig="0.994005994005994" /xcortree=2144 /SigmaFactorBS="ttcggctctttcccggcataaacaaatctccttttcggtCAT TAGACaacagcttgtacaTATAGTAAAATGAAGCTATTgaatggatgtgatgacaatg t" /listShort="yqzJ, oxaAB" /GFF_Attribute="listLong" CDS 2349184..2349471 /gene="mifM" /locus_tag="BSU_23880" /old_locus_tag="BSU23880" /experiment="publication(s) with functional evidences, PMID:19779460, 21383133, 22720735, 25313395, 25903689" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 19779460, 21383133, 22720735, 25313395, 25903689; Product type r: regulator" /codon_start=1 /transl_table=11 /product="regulator of OxaAB translation" /protein_id="YP_054586.1" /db_xref="EnsemblGenomes-Gn:BSU23880" /db_xref="EnsemblGenomes-Tr:CAE01460" /db_xref="GOA:Q7WY64" /db_xref="PDB:3J9W" /db_xref="SubtiList:BG14191" /db_xref="UniProtKB/Swiss-Prot:Q7WY64" /translation="MTMFVESINDVLFLVDFFTIILPALTAIGIAFLLRECRAGEQWK SKRTDEHQTVFHINRTDFLIIIYHRITTWIRKVFRMNSPVNDEEDAGSLLL*" gene 2349184..2349471 /gene="mifM" /locus_tag="BSU_23880" /old_locus_tag="BSU23880" promotor_-10 complement(2349368..2349387) /Source="Nicolas_upshift_promotors" /id="U1869" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.554445554445554" /psig="0.993006993006993" /xcortree=2094 /SigmaFactorBS="cttcctcatcgttcacaggcgaattcatgcggaagactttac GTATccaagttgtaatgcgATGATATATAATAATAAGAAagtctgttcggttaatgtg a" /listShort="S905, polYA" /listLong="gndA" /label="promotor_-10" upshifts complement(2349388) /Source="Nicolas_upshifts" /id="U1869" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.554445554445554" /psig="0.993006993006993" /xcortree=2094 /SigmaFactorBS="cttcctcatcgttcacaggcgaattcatgcggaagactttac GTATccaagttgtaatgcgATGATATATAATAATAAGAAagtctgttcggttaatgtg a" /listShort="S905, polYA" /listLong="gndA" promotor_-35 complement(2349403..2349406) /Source="Nicolas_upshift_promotors" /id="U1869" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.554445554445554" /psig="0.993006993006993" /xcortree=2094 /SigmaFactorBS="cttcctcatcgttcacaggcgaattcatgcggaagactttac GTATccaagttgtaatgcgATGATATATAATAATAAGAAagtctgttcggttaatgtg a" /listShort="S905, polYA" /listLong="gndA" /label="promotor_-35" CDS 2349502..2350329 /gene="oxaAB" /locus_tag="BSU_23890" /old_locus_tag="BSU23890" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:11889108, 15654078, 15671040, 15849754, 16293689, 16850406, 21204254, 24443530, 24739968, 25903689" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11889108, 15654078, 15671040, 15849754, 16293689, 16850406, 21204254, 24443530, 24739968, 25903689; Product type f: factor" /codon_start=1 /transl_table=11 /product="Sec-independent factor for membrane protein insertion (YidC/SpoIIIJ family)" /protein_id="NP_390269.1" /db_xref="EnsemblGenomes-Gn:BSU23890" /db_xref="EnsemblGenomes-Tr:CAB14320" /db_xref="GOA:P54544" /db_xref="InterPro:IPR001708" /db_xref="InterPro:IPR023060" /db_xref="InterPro:IPR028055" /db_xref="SubtiList:BG11736" /db_xref="UniProtKB/Swiss-Prot:P54544" /translation="MLKTYQKLLAMGIFLIVLCSGNAAFAATNQVGGLSNVGFFHDYL IEPFSALLKGVAGLFHGEYGLSIILVTIIVRIVVLPLFVNQFKKQRIFQEKMAVIKPQ VDSIQVKLKKTKDPEKQKELQMEMMKLYQEHNINPLAMGCLPMLIQSPIMIGLYYAIR STPEIASHSFLWFSLGQSDILMSLSAGIMYFVQAYIAQKLSAKYSAVPQNPAAQQSAK LMVFIFPVMMTIFSLNVPAALPLYWFTSGLFLTVQNIVLQMTHHKSKKTAALTESVK* " gene 2349502..2350329 /gene="oxaAB" /locus_tag="BSU_23890" /old_locus_tag="BSU23890" downshifts 2350146 /Source="Nicolas_upshifts" /id="D1248" /incds=1 /nref=4 /ntot=125 /MaxReadThrough="5.05074" /MaxDrop="3.49092" /score="-5.67811369" /energy="-7.6" /TU="U1868" /idTUdmin="U1868" /TUdmin="-176" /isTUend="FALSE" downshifts 2350322 /Source="Nicolas_upshifts" /id="D1249" /incds=0 /nref=71 /ntot=229 /MaxReadThrough="1.09826" /MaxDrop="6.56698" /score="-5.67811369" /energy="-7.6" /TU="NA" /idTUdmin="U1868" /TUdmin=0 /isTUend="TRUE" S_feature complement(2350334..2351254) /Source="Nicolas_S_feature" /locus_tag="new_2484736_2485656_c" /HighExp="LoTm, B36, M0t90, M40t90, Lbstat, M9-stat, T1.30H, B60, LBGtran, BT" /AntisenseName="yqjF" /AntisenseCor="0.18628881890353799" /AntisenseRegPval="-2.7" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S906" downshifts complement(2350377) /Source="Nicolas_upshifts" /id="D1250" /incds=0 /nref=170 /ntot=248 /MaxReadThrough="0.24428" /MaxDrop="6.31082" /score="18.1943524" /energy="-12.4" /TU="NA" /idTUdmin="U1871" /TUdmin="-1" /isTUend="TRUE" promotor_-35 2350447..2350453 /Source="Nicolas_upshift_promotors" /id="U1870" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=161 /SigmaFactorBS="cagaaatggccatcctaaaaaatagccgtatCGTTTAAaaag aaggaaatcGGGAATACCTTTACTCACCtccaaccgaaaggagcctatacgttgacgg a" /listShort="yqjF" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2350467..2350485 /Source="Nicolas_upshift_promotors" /id="U1870" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=161 /SigmaFactorBS="cagaaatggccatcctaaaaaatagccgtatCGTTTAAaaag aaggaaatcGGGAATACCTTTACTCACCtccaaccgaaaggagcctatacgttgacgg a" /listShort="yqjF" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2350476 /Source="Nicolas_upshifts" /id="U1870" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=161 /SigmaFactorBS="cagaaatggccatcctaaaaaatagccgtatCGTTTAAaaag aaggaaatcGGGAATACCTTTACTCACCtccaaccgaaaggagcctatacgttgacgg a" /listShort="yqjF" /GFF_Attribute="listLong" CDS 2350509..2351237 /gene="yqjF" /locus_tag="BSU_23900" /old_locus_tag="BSU23900" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_390270.3" /db_xref="EnsemblGenomes-Gn:BSU23900" /db_xref="EnsemblGenomes-Tr:CAB14321" /db_xref="InterPro:IPR018644" /db_xref="InterPro:IPR023375" /db_xref="SubtiList:BG11735" /db_xref="UniProtKB/Swiss-Prot:P54543" /translation="MTERFQQKNISVPDGIWIMRQTWNDVLFAHWPVDVSILRALVPS VLELDTYNGQAWISMLPFMLTNLRARYLPVIPGARAFPELNLRTYVTYKGKPGIYFFS LDADHRLAVLGARTFFHLPYFYADMKSEKNGDAIDYVSKRKNDKEAAFHAAYRPISAP FTAEKDSLDYWLTERYRLYTTYRNKLYYEDIHHHPWLLQNAEAEISVNTVTDAHGITL PESDPLLHYAKKQDVLFWPLRKWS*" gene 2350509..2351237 /gene="yqjF" /locus_tag="BSU_23900" /old_locus_tag="BSU23900" CDS complement(2351278..2352393) /gene="yqjE" /locus_tag="BSU_23910" /old_locus_tag="BSU23910" /function="16.5: Explore" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative peptidase or deacylase" /protein_id="NP_390271.2" /db_xref="EnsemblGenomes-Gn:BSU23910" /db_xref="EnsemblGenomes-Tr:CAB14322" /db_xref="GOA:P54542" /db_xref="InterPro:IPR001261" /db_xref="InterPro:IPR002933" /db_xref="InterPro:IPR008007" /db_xref="InterPro:IPR010162" /db_xref="InterPro:IPR011650" /db_xref="InterPro:IPR036264" /db_xref="SubtiList:BG11734" /db_xref="UniProtKB/Swiss-Prot:P54542" /translation="MVNEKRLLEEFLELVQIDSETKHEAEICKVLKRKFSDLGVDVKE DDTMDITGHGAGNLICTLKGTKQTDTIYFTSHMDTVVPGNGVKPVVENGYVKTDGTTI LGADDKAGLAAMFEAIKVLKEENIEHGTIEFIITVGEESGLIGAKALDRSMITASYGY ALDSDGKVGNIIVAAPTQAKVRAAIFGKTAHAGVEPEKGISAITIASKAISKMPLGRI DEETTANIGRFEGGTQTNIVCDEVHILAEARSLVPEKMEAQVQKMKAAFEEAAADMGG RAEVEIEVMYPGFKYQDGDQVVEIAKKAAAKIGRPSELQTSGGGSDANVIAGHGIPTV NLAVGYEQIHTKNEKMPIEELVKTAEMVVAIIEEAAK*" gene complement(2351278..2352393) /gene="yqjE" /locus_tag="BSU_23910" /old_locus_tag="BSU23910" downshifts complement(2351299) /Source="Nicolas_upshifts" /id="D1251" /incds=0 /nref=23 /ntot=203 /MaxReadThrough="3.90071" /MaxDrop="3.95711" /score="11.6635037" /energy="-10.6" /TU="U1871" /idTUdmin="U1871" /TUdmin="-923" /isTUend="FALSE" CDS complement(2352411..2353934) /gene="yqjD" /locus_tag="BSU_23920" /old_locus_tag="BSU23920" /EC_number="6.4.1.3" /function="16.5: Explore" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative propionyl-CoA carboxylase beta chain" /protein_id="NP_390272.2" /db_xref="EnsemblGenomes-Gn:BSU23920" /db_xref="EnsemblGenomes-Tr:CAB14323" /db_xref="GOA:P54541" /db_xref="InterPro:IPR000438" /db_xref="InterPro:IPR011762" /db_xref="InterPro:IPR011763" /db_xref="InterPro:IPR029045" /db_xref="InterPro:IPR034733" /db_xref="SubtiList:BG11733" /db_xref="UniProtKB/Swiss-Prot:P54541" /translation="MNEHMDHFYTKRKQAEEGGGREKLAQQRQKGKLTARERIIFLLD QDSFIELHPFMESQVLTREQRMLGDGVVTGYGTIDGRSVYVFAQDFTVYGGALGETHA RKICALMDLAAKNKAPIIGLNDSGGARIQEGVLSLDGYGHIFYRNVLYSGVIPQISVI LGPCAGGAVYSPALTDFIFMAEQTGRMFITGPKVIEKVTGEQVDAESLGGAGIHNAVS GNAHFSGHTEKEVLTGVRKLLSYLPLNGRTTEPKPEKEASRPLLNRLVPADTTKPYDV RKVIRELADPQSFFEIQPFFAKNIVIGFARLGEKAIGIVASQPKHLAGSLTIDAADKA ARFIRFCDAFDIPLLTVEDVPGFLPGIQQEHNGIIRHGAKLLFAYAEATVPKVTLIIR KAYGGAYVAMNSKAIGADLVFAWPNAEIAVMGPEGAASILYEKEIKASADPQKTKREK TAEYKKQNAGPYKAAACGMVDDIILPEESRGRLIQAFHMLTHKTEERPKKKHGNIPL* " gene complement(2352411..2353934) /gene="yqjD" /locus_tag="BSU_23920" /old_locus_tag="BSU23920" promotor_-10 complement(2353517..2353536) /Source="Nicolas_upshift_promotors" /id="U1871" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.504495504495505" /psig="0.999000999001" /xcortree=1916 /SigmaFactorBS="agcaaaaaataaggcgccgattatcgggctgaatgactcagg tgGTGCGagaattcaagagggTGTGTTATCATTAGATGGATacggtcacatattttac c" /listShort="yqjE, S906" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2353539) /Source="Nicolas_upshifts" /id="U1871" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.504495504495505" /psig="0.999000999001" /xcortree=1916 /SigmaFactorBS="agcaaaaaataaggcgccgattatcgggctgaatgactcagg tgGTGCGagaattcaagagggTGTGTTATCATTAGATGGATacggtcacatattttac c" /listShort="yqjE, S906" /GFF_Attribute="listLong" promotor_-35 complement(2353551..2353555) /Source="Nicolas_upshift_promotors" /id="U1871" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.504495504495505" /psig="0.999000999001" /xcortree=1916 /SigmaFactorBS="agcaaaaaataaggcgccgattatcgggctgaatgactcagg tgGTGCGagaattcaagagggTGTGTTATCATTAGATGGATacggtcacatattttac c" /listShort="yqjE, S906" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2353927..2354349) /gene="yqjC" /locus_tag="BSU_23930" /old_locus_tag="BSU23930" /EC_number="5.1.99.1" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative methylmalonyl-CoA epimerase" /protein_id="NP_390273.2" /db_xref="EnsemblGenomes-Gn:BSU23930" /db_xref="EnsemblGenomes-Tr:CAB14324" /db_xref="GOA:P54540" /db_xref="InterPro:IPR017515" /db_xref="InterPro:IPR018146" /db_xref="InterPro:IPR029068" /db_xref="SubtiList:BG11732" /db_xref="UniProtKB/Swiss-Prot:P54540" /translation="MNRLDHIGIAVFSIKDARSFYENVLGLAFLHQETVEEQKVNVAF FQAGSVKLELIEPLTADSPVHLFLEKKGQGLHHIAFLCNCLSEQLQALSDQHVQLIDR FPRQGANGKKIAFISPRETNGVLVELCEPKGDQHNEHE*" gene complement(2353927..2354349) /gene="yqjC" /locus_tag="BSU_23930" /old_locus_tag="BSU23930" promotor_-35 2354378..2354385 /Source="Nicolas_upshift_promotors" /id="U1872" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.963036963036963" /psig=1 /xcortree=1904 /SigmaFactorBS="catccctgctttcgctaatagatatCGCTTGTCcgcccattc aaaaCACGCTAAAATATAGACAGAttgtttaaggagtgaaaatcatgtctcaaaaact g" /listShort="S907, S908" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2354399..2354418 /Source="Nicolas_upshift_promotors" /id="U1872" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.963036963036963" /psig=1 /xcortree=1904 /SigmaFactorBS="catccctgctttcgctaatagatatCGCTTGTCcgcccattc aaaaCACGCTAAAATATAGACAGAttgtttaaggagtgaaaatcatgtctcaaaaact g" /listShort="S907, S908" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 2354413..2354566 /Source="Nicolas_S_feature" /locus_tag="new_2488815_2488968" /HighExp="LPhT, Etha, dia15, Salt, M9-stat, LBGstat, Heat, BC, T-0.40H, HiOs" /AntisenseName="yqjB" /AntisenseCor="-0.57221813594264503" /AntisenseRegPval="-24.1" /CDS_PredictionProba="0.99822200000000005" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S907" upshifts 2354413 /Source="Nicolas_upshifts" /id="U1872" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.963036963036963" /psig=1 /xcortree=1904 /SigmaFactorBS="catccctgctttcgctaatagatatCGCTTGTCcgcccattc aaaaCACGCTAAAATATAGACAGAttgtttaaggagtgaaaatcatgtctcaaaaact g" /listShort="S907, S908" /GFF_Attribute="listLong" downshifts 2354523 /Source="Nicolas_upshifts" /id="D1252" /incds=0 /nref=1 /ntot=140 /MaxReadThrough="3.88708" /MaxDrop="3.25163" /score="3.10927996" /energy="-7" /TU="U1872" /idTUdmin="U1872" /TUdmin="-638" /isTUend="FALSE" CDS complement(2354551..2355081) /gene="yqjB" /locus_tag="BSU_23940" /old_locus_tag="BSU23940" /EC_number="2.-.-.-" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative L,D-transpeptidase" /protein_id="NP_390274.1" /db_xref="EnsemblGenomes-Gn:BSU23940" /db_xref="EnsemblGenomes-Tr:CAB14325" /db_xref="GOA:P54539" /db_xref="InterPro:IPR005490" /db_xref="SubtiList:BG11731" /db_xref="UniProtKB/Swiss-Prot:P54539" /translation="MRFFLCSIFMMISPIWPLGENPLPGDPYVIVNKRTNELAVILDN KVEGVYSVATGKTDDLTPEGEFSVTVKAENPYYRKKNIEGGSPDNPLGARWIGFDAKG TDGRIYGIHGTNREESVGKFVSNGCIRMHNDEVVHLFQTIPVGTRVLITDDNRSFEEI AIEHKALIKKQDIPIE*" gene complement(2354551..2355081) /gene="yqjB" /locus_tag="BSU_23940" /old_locus_tag="BSU23940" S_feature 2354568..2355203 /Source="Nicolas_S_feature" /locus_tag="new_2488970_2489605" /HighExp="LPhT, H2O2, BC, Salt, dia15, M9-stat, Heat, LBGstat, T5.0H, Etha" /AntisenseName="yqjB" /AntisenseCor="-0.31126010332536502" /AntisenseRegPval="-6.7" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S908" promotor_-10 complement(2355098..2355109) /Source="Nicolas_upshift_promotors" /id="U1873" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=825 /SigmaFactorBS="aaaggaataaaagcgcaaaaatcactcggatgattCGCATGA gctcttccttcattGGTCAACCTAATgaaaaaggaggagcttatgcgttttttcttat g" /listShort="yqjB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2355105) /Source="Nicolas_upshifts" /id="U1873" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=825 /SigmaFactorBS="aaaggaataaaagcgcaaaaatcactcggatgattCGCATGA gctcttccttcattGGTCAACCTAATgaaaaaggaggagcttatgcgttttttcttat g" /listShort="yqjB" /GFF_Attribute="listLong" promotor_-35 complement(2355124..2355130) /Source="Nicolas_upshift_promotors" /id="U1873" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=825 /SigmaFactorBS="aaaggaataaaagcgcaaaaatcactcggatgattCGCATGA gctcttccttcattGGTCAACCTAATgaaaaaggaggagcttatgcgttttttcttat g" /listShort="yqjB" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2355133..2356101) /gene="yqjA" /locus_tag="BSU_23950" /old_locus_tag="BSU23950" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_390275.2" /db_xref="EnsemblGenomes-Gn:BSU23950" /db_xref="EnsemblGenomes-Tr:CAB14326" /db_xref="GOA:P54538" /db_xref="InterPro:IPR010343" /db_xref="InterPro:IPR021062" /db_xref="SubtiList:BG11730" /db_xref="UniProtKB/Swiss-Prot:P54538" /translation="MFKIGYRTIKTALGTALAIYISQLLHLQNFASAGIITILCIQIT QKRSLQASWARFSACCLAIAFSYLFFELIGYHPFVIGALLLIFIPITVLLKINEGIVT SSVIILHLYMSGGITPTFIWNEVQLITVGIGVALLMNLYMPSLDRKLIAYRKKIEDNF AVIFAEIERYLLTGEQDWSGKEIPETHQLITEAKNLAYRDVQNHILRYENLHYHYFKM REKQFEIIERLLPKVTSISITVDQGKMIAEFIHDLREAIHPGNTAYKFLKRLADMRKE FEEMPLPATREEFEARAALFHLLGEMEQYLVIKSYFKGIKAQKSLG*" gene complement(2355133..2356101) /gene="yqjA" /locus_tag="BSU_23950" /old_locus_tag="BSU23950" downshifts complement(2355149) /Source="Nicolas_upshifts" /id="D1253" /incds=0 /nref=79 /ntot=223 /MaxReadThrough="2.22356" /MaxDrop="3.94894" /score="1.98299685" /energy="-14.1" /TU="NA" /idTUdmin="U1874" /TUdmin=0 /isTUend="TRUE" CDS complement(2356172..2356894) /gene="artR" /locus_tag="BSU_23960" /old_locus_tag="BSU23960" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:10939241, 11423008" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10939241, 11423008; Product type t: transporter" /codon_start=1 /transl_table=11 /product="high affinity arginine ABC transporter (ATP-binding protein)" /protein_id="NP_390276.1" /db_xref="EnsemblGenomes-Gn:BSU23960" /db_xref="EnsemblGenomes-Tr:CAB14327" /db_xref="GOA:P54537" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR017871" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR030679" /db_xref="SubtiList:BG11729" /db_xref="UniProtKB/Swiss-Prot:P54537" /translation="MIKVEKLSKSFGKHEVLKNISTTIAEGEVVAVIGPSGSGKSTFL RCLNLLEKPNGGTITIKDTEITKPKTNTLKVRENIGMVFQHFHLFPHKTVLENIMYAP VNVKKESKQAAQEKAEDLLRKVGLFEKRNDYPNRLSGGQKQRVAIARALAMNPDIMLF DEPTSALDPEMVKEVLQVMKELVETGMTMVIVTHEMGFAKEVADRVLFMDQGMIVEDG NPKEFFMSPKSKRAQDFLEKIL*" gene complement(2356172..2356894) /gene="artR" /locus_tag="BSU_23960" /old_locus_tag="BSU23960" downshifts complement(2356183) /Source="Nicolas_upshifts" /id="D1254" /incds=0 /nref=30 /ntot=152 /MaxReadThrough="4.81216" /MaxDrop="4.0342" /score="0.346345754" /energy="-7" /TU="U1874" /idTUdmin="U1874" /TUdmin="-1034" /isTUend="FALSE" CDS complement(2356887..2357546) /gene="artQ" /locus_tag="BSU_23970" /old_locus_tag="BSU23970" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:10939241, 11423008, 15849754, 16850406" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10939241, 11423008, 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="high affinity arginine ABC transporter (permease)" /protein_id="NP_390277.1" /db_xref="EnsemblGenomes-Gn:BSU23970" /db_xref="EnsemblGenomes-Tr:CAB14328" /db_xref="GOA:P54536" /db_xref="InterPro:IPR000515" /db_xref="InterPro:IPR010065" /db_xref="InterPro:IPR035906" /db_xref="SubtiList:BG11728" /db_xref="UniProtKB/Swiss-Prot:P54536" /translation="MNLDFSATIPQIPFILEGLAITLKIVVVSAIIGLILGIVLSLCK ISTFRPFIWIADFYTSVFRGTPLVLQLMIVYFGLPQLLGFQIDQFWAAVVALSLNSAA YVSEIIRAGINAIDKGQKEAAVALGVPYGKMMKDLLLPQAFKNISPAIVNELITLTKE SAIVTVIGLGDVMRRAYQAGAATYNYLEPLIIAGLIYYVLVLILTFIGKAVERKLKSN D*" gene complement(2356887..2357546) /gene="artQ" /locus_tag="BSU_23970" /old_locus_tag="BSU23970" S_feature complement(2357547..2357626) /Source="Nicolas_S_feature" /locus_tag="new_2491949_2492028_c" /HighExp="S1, S2, ferm, MG 15, Fru, Glu, BMM, S3, UNK1, S5" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="SigA" /TUlongPSig=1 /label="S909" CDS complement(2357627..2358394) /gene="artP" /locus_tag="BSU_23980" /old_locus_tag="BSU23980" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:10939241, 11423008" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10939241, 11423008; Product type t: transporter" /codon_start=1 /transl_table=11 /product="high affinity arginine ABC transporter binding lipoprotein" /protein_id="NP_390278.1" /db_xref="EnsemblGenomes-Gn:BSU23980" /db_xref="EnsemblGenomes-Tr:CAB14329" /db_xref="GOA:P54535" /db_xref="InterPro:IPR001320" /db_xref="InterPro:IPR001638" /db_xref="InterPro:IPR018313" /db_xref="SubtiList:BG11727" /db_xref="UniProtKB/Swiss-Prot:P54535" /translation="MKKWLLLLVAACITFALTACGSSNSGSESGKKKLIMGTSADYKP FEYKEGDNIVGFDVELAKALAKKAGYEIEVQDMDFNSLITALKSKQVDLVLSGMTPTP ERKKQVDFSDVYYTANHMIVSKKDSGIQSLKDLKGKTVGVQLGSIQEEKGKELSPEYG FKTEDRNRISDLVQEIKSDRFDAAIIEDIVAEGYFKSNDDLQGFVIPDAKAEEAGSAI AFRKDSELTDKFNKALKEMEDNGELEKLKKKWFTGEK*" gene complement(2357627..2358394) /gene="artP" /locus_tag="BSU_23980" /old_locus_tag="BSU23980" promotor_-10 complement(2358444..2358463) /Source="Nicolas_upshift_promotors" /id="U1874" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.94105894105894" /psig=1 /xcortree=2912 /SigmaFactorBS="gaaagataagcctaaagataatttttaaaaatagTATTGCAT aaaaatgagaaactGTTTAAAATACAAATTAACGaataaatattcaaatacaccaaaa g" /listShort="artP, S909, artQ, artR, yqjA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2358459) /Source="Nicolas_upshifts" /id="U1874" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.94105894105894" /psig=1 /xcortree=2912 /SigmaFactorBS="gaaagataagcctaaagataatttttaaaaatagTATTGCAT aaaaatgagaaactGTTTAAAATACAAATTAACGaataaatattcaaatacaccaaaa g" /listShort="artP, S909, artQ, artR, yqjA" /GFF_Attribute="listLong" promotor_-35 complement(2358478..2358485) /Source="Nicolas_upshift_promotors" /id="U1874" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.94105894105894" /psig=1 /xcortree=2912 /SigmaFactorBS="gaaagataagcctaaagataatttttaaaaatagTATTGCAT aaaaatgagaaactGTTTAAAATACAAATTAACGaataaatattcaaatacaccaaaa g" /listShort="artP, S909, artQ, artR, yqjA" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2358662..2359099) /gene="brxB" /locus_tag="BSU_23990" /old_locus_tag="BSU23990" /experiment="publication(s) with functional evidences, PMID:21749987, 24313874, 28301954" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 21749987, 24313874, 28301954; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="bacilliredoxin B (de-bacillithiolation)" /protein_id="NP_390279.1" /db_xref="EnsemblGenomes-Gn:BSU23990" /db_xref="EnsemblGenomes-Tr:CAB14330" /db_xref="InterPro:IPR009474" /db_xref="SubtiList:BG11726" /db_xref="UniProtKB/Swiss-Prot:P54534" /translation="MNMDFNLFMNDIVRQARQEITAAGYTELKTAEEVDEALTKKGTT LVMVNSVCGCAGGIARPAAYHSVHYDKRPDQLVTVFAGQDKEATARARDYFEGYPPSS PSFAILKDGKIMKMVERHEIEGHEPMAVVAKLQEAFEEYCEEV*" gene complement(2358662..2359099) /gene="brxB" /locus_tag="BSU_23990" /old_locus_tag="BSU23990" downshifts complement(2358671) /Source="Nicolas_upshifts" /id="D1255" /incds=0 /nref=252 /ntot=266 /MaxReadThrough="3.9242" /MaxDrop="7.06654" /score="21.489397" /energy="-11.8" /TU="U1875" /idTUdmin="U1875" /TUdmin="-200" /isTUend="FALSE" promotor_-10 complement(2359123..2359142) /Source="Nicolas_upshift_promotors" /id="U1875" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.99100899100899" /psig=1 /xcortree=1935 /SigmaFactorBS="agtaaacgaagagcaaaaaaagtgcacggcgaagcaaagtCA TTTGCCgatatggacgtttcCTTGCTATCATAAGAACAGAtgatgaaaaaggagaggt c" /listShort="yqiW" /listLong="artP, S909, artQ, artR, yqjA" /label="promotor_-10" upshifts complement(2359144) /Source="Nicolas_upshifts" /id="U1875" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.99100899100899" /psig=1 /xcortree=1935 /SigmaFactorBS="agtaaacgaagagcaaaaaaagtgcacggcgaagcaaagtCA TTTGCCgatatggacgtttcCTTGCTATCATAAGAACAGAtgatgaaaaaggagaggt c" /listShort="yqiW" /listLong="artP, S909, artQ, artR, yqjA" promotor_-35 complement(2359157..2359164) /Source="Nicolas_upshift_promotors" /id="U1875" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.99100899100899" /psig=1 /xcortree=1935 /SigmaFactorBS="agtaaacgaagagcaaaaaaagtgcacggcgaagcaaagtCA TTTGCCgatatggacgtttcCTTGCTATCATAAGAACAGAtgatgaaaaaggagaggt c" /listShort="yqiW" /listLong="artP, S909, artQ, artR, yqjA" /label="promotor_-35" promotor_-35 2359197..2359203 /Source="Nicolas_upshift_promotors" /id="U1876" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=198 /SigmaFactorBS="cggcaaatgactttgcttcgccgtgcactttttttgctcttC GTTTACtgcttacagaaaaaGGGGATTATATAACCAGAAgtaaaataaaggagcagtt g" /listShort="bmrU, bmr, bmrR" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 2359216 /Source="Nicolas_upshifts" /id="U1876" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=198 /SigmaFactorBS="cggcaaatgactttgcttcgccgtgcactttttttgctcttC GTTTACtgcttacagaaaaaGGGGATTATATAACCAGAAgtaaaataaaggagcagtt g" /listShort="bmrU, bmr, bmrR" /GFF_Attribute="listLong" promotor_-10 2359218..2359236 /Source="Nicolas_upshift_promotors" /id="U1876" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=198 /SigmaFactorBS="cggcaaatgactttgcttcgccgtgcactttttttgctcttC GTTTACtgcttacagaaaaaGGGGATTATATAACCAGAAgtaaaataaaggagcagtt g" /listShort="bmrU, bmr, bmrR" /GFF_Attribute="listLong" /label="promotor_-10" CDS 2359260..2360153 /gene="bmrU" /locus_tag="BSU_24000" /old_locus_tag="BSU24000" /EC_number="2.7.1.-" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 7961792, 8098708, 10220166, 17114254, 17535816; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative lipid kinase BmrU" /protein_id="NP_390280.2" /db_xref="EnsemblGenomes-Gn:BSU24000" /db_xref="EnsemblGenomes-Tr:CAB14331" /db_xref="GOA:P39074" /db_xref="InterPro:IPR001206" /db_xref="InterPro:IPR005218" /db_xref="InterPro:IPR016064" /db_xref="InterPro:IPR017438" /db_xref="SubtiList:BG10302" /db_xref="UniProtKB/Swiss-Prot:P39074" /translation="MSHRKALLIHNGNAGNKNIEKALGAVVPVLSHHLDEVIIKQTKK KDDAYHFCRSIDDSVDTVFILGGDGTIHQCINAISALERKPAVGILPGGTCNDFSRVL GIPQNLAKAAEALMAGKKTSVDVCQMNDRYFLNFWGIGLIAETSNQINETEKALLGKI SYFTSALRTVSSAASFPMTLKIDGEEIKEEAVMLLVMNGQYIGTNRIPLPDASIEDGL LDVLICRNTNLTALRELMSMEQGSIDRFTGELSYVQASRIEIETDTAKKADMDGEVYT HTPAVIQVLPQHIDMLVPANE*" gene 2359260..2360153 /gene="bmrU" /locus_tag="BSU_24000" /old_locus_tag="BSU24000" promotor_-35 2360186..2360193 /Source="Nicolas_upshift_promotors" /id="U1877" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.97002997002997" /psig="0.993006993006993" /xcortree=1530 /SigmaFactorBS="tcataaggctttagaaagattttgcaaatCCGTTGACtctcc cctaggaggaGGTCTTACAGTATAAGGGATacacacttgaaaaaggggaagtcatatg g" /listShort="bmr, bmrR" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2360209..2360228 /Source="Nicolas_upshift_promotors" /id="U1877" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.97002997002997" /psig="0.993006993006993" /xcortree=1530 /SigmaFactorBS="tcataaggctttagaaagattttgcaaatCCGTTGACtctcc cctaggaggaGGTCTTACAGTATAAGGGATacacacttgaaaaaggggaagtcatatg g" /listShort="bmr, bmrR" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2360217 /Source="Nicolas_upshifts" /id="U1877" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.97002997002997" /psig="0.993006993006993" /xcortree=1530 /SigmaFactorBS="tcataaggctttagaaagattttgcaaatCCGTTGACtctcc cctaggaggaGGTCTTACAGTATAAGGGATacacacttgaaaaaggggaagtcatatg g" /listShort="bmr, bmrR" /GFF_Attribute="listLong" CDS 2360254..2361423 /gene="bmr" /locus_tag="BSU_24010" /old_locus_tag="BSU24010" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:10200972, 10961951, 11321573, 15849754, 16850406, 25756668" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10200972, 10961951, 11321573, 15849754, 16850406, 25756668; Product type t : transporter" /codon_start=1 /transl_table=11 /product="multidrug-efflux transporter" /protein_id="NP_390281.2" /db_xref="EnsemblGenomes-Gn:BSU24010" /db_xref="EnsemblGenomes-Tr:CAB14332" /db_xref="GOA:P33449" /db_xref="InterPro:IPR001958" /db_xref="InterPro:IPR005829" /db_xref="InterPro:IPR011701" /db_xref="InterPro:IPR020846" /db_xref="InterPro:IPR036259" /db_xref="SubtiList:BG10303" /db_xref="UniProtKB/Swiss-Prot:P33449" /translation="MEKKNITLTILLTNLFIAFLGIGLVIPVTPTIMNELHLSGTAVG YMVACFAITQLIVSPIAGRWVDRFGRKIMIVIGLLFFSVSEFLFGIGKTVEMLFISRM LGGISAAFIMPGVTAFIADITTIKTRPKALGYMSAAISTGFIIGPGIGGFLAEVHSRL PFFFAAAFALLAAILSILTLREPERNPENQEIKGQKTGFKRIFAPMYFIAFLIILISS FGLASFESLFALFVDHKFGFTASDIAIMITGGAIVGAITQVVLFDRFTRWFGEIHLIR YSLILSTSLVFLLTTVHSYVAILLVTVTVFVGFDLMRPAVTTYLSKIAGNEQGFAGGM NSMFTSIGNVFGPIIGGMLFDIDVNYPFYFATVTLAIGIALTIAWKAPAHLKAST*" gene 2360254..2361423 /gene="bmr" /locus_tag="BSU_24010" /old_locus_tag="BSU24010" downshifts 2361406 /Source="Nicolas_upshifts" /id="D1256" /incds=0 /nref=6 /ntot=31 /MaxReadThrough="4.82186" /MaxDrop="5.02667" /score="-1.94257488" /energy="-18" /TU="U1876,U1877" /idTUdmin="U1876" /TUdmin="-924" /isTUend="FALSE" CDS 2361496..2362332 /gene="bmrR" /locus_tag="BSU_24020" /old_locus_tag="BSU24020" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:11201751, 11839496, 12682015, 14985361, 18658145, 21690368" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11201751, 11839496, 12682015, 14985361, 18658145, 21690368; Product type r : regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator (MerR family)" /protein_id="NP_390282.2" /db_xref="EnsemblGenomes-Gn:BSU24020" /db_xref="EnsemblGenomes-Tr:CAB14333" /db_xref="GOA:P39075" /db_xref="InterPro:IPR000551" /db_xref="InterPro:IPR009061" /db_xref="InterPro:IPR011256" /db_xref="InterPro:IPR029442" /db_xref="PDB:1BOW" /db_xref="PDB:1EXI" /db_xref="PDB:1EXJ" /db_xref="PDB:1R8E" /db_xref="PDB:2BOW" /db_xref="PDB:3D6Y" /db_xref="PDB:3D6Z" /db_xref="PDB:3D70" /db_xref="PDB:3D71" /db_xref="PDB:3IAO" /db_xref="PDB:3Q1M" /db_xref="PDB:3Q2Y" /db_xref="PDB:3Q3D" /db_xref="PDB:3Q5P" /db_xref="PDB:3Q5R" /db_xref="PDB:3Q5S" /db_xref="SubtiList:BG10304" /db_xref="UniProtKB/Swiss-Prot:P39075" /translation="MKESYYSIGEVSKLANVSIKALRYYDKIDLFKPAYVDPDTSYRY YTDSQLIHLDLIKSLKYIGTPLEEMKKAQDLEMEELFAFYTEQERQIREKLDFLSALE QTISLVKKRMKRQMEYPALGEVFVLDEEEIRIIQTEAEGIGPENVLNASYSKLKKFIE SADGFTNNSYGATFSFQPYTSIDEMTYRHIFTPVLTNKQISSITPDMEITTIPKGRYA CIAYNFSPEHYFLNLQKLIKYIADRQLTVVSDVYELIIPIHYSPKKQEEYRVEMKIRI AE*" gene 2361496..2362332 /gene="bmrR" /locus_tag="BSU_24020" /old_locus_tag="BSU24020" downshifts 2362330 /Source="Nicolas_upshifts" /id="D1257" /incds=0 /nref=5 /ntot=156 /MaxReadThrough="4.1979" /MaxDrop="4.72542" /score="5.00815505" /energy="-15.7" /TU="NA" /idTUdmin="U1876" /TUdmin=0 /isTUend="TRUE" downshifts complement(2362394) /Source="Nicolas_upshifts" /id="D1258" /incds=0 /nref=15 /ntot=247 /MaxReadThrough="3.01431" /MaxDrop="6.04069" /score="8.5296919" /energy="-16.8" /TU="U1879" /idTUdmin="U1878" /TUdmin="-10" /isTUend="TRUE" CDS complement(2362394..2363668) /gene="bkdB" /locus_tag="BSU_24030" /old_locus_tag="BSU24030" /EC_number="2.3.1.168" /function="16.11: Scavenge (Catabolism)" /function="16.2: Construct biomass (Anabolism)" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:10094682, 12427936, 15241682, 22720735, 28371347" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10094682, 12427936, 15241682, 22720735, 28371347; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="branched-chain alpha-keto acid dehydrogenase E2 subunit (lipoamide acyltransferase)" /protein_id="NP_390283.1" /db_xref="EnsemblGenomes-Gn:BSU24030" /db_xref="EnsemblGenomes-Tr:CAB14334" /db_xref="GOA:P37942" /db_xref="InterPro:IPR000089" /db_xref="InterPro:IPR001078" /db_xref="InterPro:IPR003016" /db_xref="InterPro:IPR004167" /db_xref="InterPro:IPR011053" /db_xref="InterPro:IPR036625" /db_xref="SubtiList:BG10305" /db_xref="UniProtKB/Swiss-Prot:P37942" /translation="MAIEQMTMPQLGESVTEGTISKWLVAPGDKVNKYDPIAEVMTDK VNAEVPSSFTGTITELVGEEGQTLQVGEMICKIETEGANPAEQKQEQPAASEAAENPV AKSAGAADQPNKKRYSPAVLRLAGEHGIDLDQVTGTGAGGRITRKDIQRLIETGGVQE QNPEELKTAAPAPKSASKPEPKEETSYPASAAGDKEIPVTGVRKAIASNMKRSKTEIP HAWTMMEVDVTNMVAYRNSIKDSFKKTEGFNLTFFAFFVKAVAQALKEFPQMNSMWAG DKIIQKKDINISIAVATEDSLFVPVIKNADEKTIKGIAKDITGLAKKVRDGKLTADDM QGGTFTVNNTGSFGSVQSMGIINYPQAAILQVESIVKRPVVMDNGMIAVRDMVNLCLS LDHRVLDGLVCGRFLGRVKQILESIDEKTSVY*" gene complement(2362394..2363668) /gene="bkdB" /locus_tag="BSU_24030" /old_locus_tag="BSU24030" CDS complement(2363691..2364674) /gene="bkdAB" /locus_tag="BSU_24040" /old_locus_tag="BSU24040" /EC_number="1.2.4.4" /function="16.2: Construct biomass (Anabolism)" /function="16.8: Protect" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:10094682, 12427936, 15241682, 28371347" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10094682, 12427936, 15241682, 28371347; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="branched-chain alpha-keto acid dehydrogenase E1 subunit" /protein_id="NP_390284.1" /db_xref="EnsemblGenomes-Gn:BSU24040" /db_xref="EnsemblGenomes-Tr:CAB14335" /db_xref="GOA:P37941" /db_xref="InterPro:IPR005475" /db_xref="InterPro:IPR009014" /db_xref="InterPro:IPR029061" /db_xref="InterPro:IPR033248" /db_xref="SubtiList:BG10306" /db_xref="UniProtKB/Swiss-Prot:P37941" /translation="MSVMSYIDAINLAMKEEMERDSRVFVLGEDVGRKGGVFKATAGL YEQFGEERVMDTPLAESAIAGVGIGAAMYGMRPIAEMQFADFIMPAVNQIISEAAKIR YRSNNDWSCPIVVRAPYGGGVHGALYHSQSVEAIFANQPGLKIVMPSTPYDAKGLLKA AVRDEDPVLFFEHKRAYRLIKGEVPADDYVLPIGKADVKREGDDITVITYGLCVHFAL QAAERLEKDGISAHVVDLRTVYPLDKEAIIEAASKTGKVLLVTEDTKEGSIMSEVAAI ISEHCLFDLDAPIKRLAGPDIPAMPYAPTMEKYFMVNPDKVEAAMRELAEF*" gene complement(2363691..2364674) /gene="bkdAB" /locus_tag="BSU_24040" /old_locus_tag="BSU24040" CDS complement(2364688..2365680) /gene="bkdAA" /locus_tag="BSU_24050" /old_locus_tag="BSU24050" /EC_number="1.2.4.4" /function="16.11: Scavenge (Catabolism)" /function="16.2: Construct biomass (Anabolism)" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:10094682, 12427936, 15241682, 22720735, 28371347" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10094682, 12427936, 15241682, 22720735, 28371347; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="branched-chain alpha-keto acid dehydrogenase E1 subunit" /protein_id="NP_390285.1" /db_xref="EnsemblGenomes-Gn:BSU24050" /db_xref="EnsemblGenomes-Tr:CAB14336" /db_xref="GOA:P37940" /db_xref="InterPro:IPR001017" /db_xref="InterPro:IPR029061" /db_xref="InterPro:IPR034616" /db_xref="SubtiList:BG10307" /db_xref="UniProtKB/Swiss-Prot:P37940" /translation="MSTNRHQALGLTDQEAVDMYRTMLLARKIDERMWLLNRSGKIPF VISCQGQEAAQVGAAFALDREMDYVLPYYRDMGVVLAFGMTAKDLMMSGFAKAADPNS GGRQMPGHFGQKKNRIVTGSSPVTTQVPHAVGIALAGRMEKKDIAAFVTFGEGSSNQG DFHEGANFAAVHKLPVIFMCENNKYAISVPYDKQVACENISDRAIGYGMPGVTVNGND PLEVYQAVKEARERARRGEGPTLIETISYRLTPHSSDDDDSSYRGREEVEEAKKSDPL LTYQAYLKETGLLSDEIEQTMLDEIMAIVNEATDEAENAPYAAPESALDYVYAK*" gene complement(2364688..2365680) /gene="bkdAA" /locus_tag="BSU_24050" /old_locus_tag="BSU24050" CDS complement(2365702..2367126) /gene="lpdV" /locus_tag="BSU_24060" /old_locus_tag="BSU24060" /EC_number="1.8.1.4" /function="16.2: Construct biomass (Anabolism)" /function="16.8: Protect" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:10094682, 12427936, 15241682, 28371347" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10094682, 12427936, 15241682, 28371347; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="branched-chain alpha-keto acid dehydrogenase E3 subunit (dihydrolipoamide dehydrogenase)" /protein_id="NP_390286.2" /db_xref="EnsemblGenomes-Gn:BSU24060" /db_xref="EnsemblGenomes-Tr:CAB14337" /db_xref="GOA:P54533" /db_xref="InterPro:IPR001100" /db_xref="InterPro:IPR004099" /db_xref="InterPro:IPR006258" /db_xref="InterPro:IPR012999" /db_xref="InterPro:IPR016156" /db_xref="InterPro:IPR023753" /db_xref="InterPro:IPR036188" /db_xref="SubtiList:BG11725" /db_xref="UniProtKB/Swiss-Prot:P54533" /translation="MATEYDVVILGGGTGGYVAAIRAAQLGLKTAVVEKEKLGGTCLH KGCIPSKALLRSAEVYRTAREADQFGVETAGVSLNFEKVQQRKQAVVDKLAAGVNHLM KKGKIDVYTGYGRILGPSIFSPLPGTISVERGNGEENDMLIPKQVIIATGSRPRMLPG LEVDGKSVLTSDEALQMEELPQSIIIVGGGVIGIEWASMLHDFGVKVTVIEYADRILP TEDLEISKEMESLLKKKGIQFITGAKVLPDTMTKTSDDISIQAEKDGETVTYSAEKML VSIGRQANIEGIGLENTDIVTENGMISVNESCQTKESHIYAIGDVIGGLQLAHVASHE GIIAVEHFAGLNPHPLDPTLVPKCIYSSPEAASVGLTEDEAKANGHNVKIGKFPFMAI GKALVYGESDGFVKIVADRDTDDILGVHMIGPHVTDMISEAGLAKVLDATPWEVGQTI HPHPTLSEAIGEAALAADGKAIHF*" gene complement(2365702..2367126) /gene="lpdV" /locus_tag="BSU_24060" /old_locus_tag="BSU24060" CDS complement(2367147..2368238) /gene="buk" /locus_tag="BSU_24070" /old_locus_tag="BSU24070" /EC_number="2.7.2.-" /EC_number="2.7.2.7" /function="16.2: Construct biomass (Anabolism)" /function="16.8: Protect" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:10094682, 12427936, 15241682" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10094682, 12427936, 15241682; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="branched-chain fatty-acid kinase" /protein_id="NP_390287.2" /db_xref="EnsemblGenomes-Gn:BSU24070" /db_xref="EnsemblGenomes-Tr:CAB14338" /db_xref="GOA:P54532" /db_xref="InterPro:IPR000890" /db_xref="InterPro:IPR011245" /db_xref="InterPro:IPR023865" /db_xref="SubtiList:BG11724" /db_xref="UniProtKB/Swiss-Prot:P54532" /translation="MKVLHDEKRILTINPGSTSTKIGVFHNERSIFEKTLRHNIEELQ RFDRIIDQYEFRKNHILETLHEQGINISKFDAVCARGGLLRPIEGGTYVVNDEMIEDL KSGYAGQHASNLGGIIAREIADGLNIPSYIVDPVVVDEMSVLAKVSGMPEIERKSIFH ALNQKAVARKAAASLGKRYENMKMIITHMGGGITIGVHDRGRVVDVNNGLHGEGPFSP ERAGTVPAGDLVDLCFSGEYTKEEIMKKLVGTGGLLGYLGTNDAVKVEQMIQGGDEKA RFIYDAMAYQVAKEIGAASAALKGEVEAIVLTGGLAYGKSFVSAIRSYIDWISDVLVY PGENELQSLAQGALRVLQGEEQSKQYRIE*" gene complement(2367147..2368238) /gene="buk" /locus_tag="BSU_24070" /old_locus_tag="BSU24070" CDS complement(2368257..2369351) /gene="bcd" /locus_tag="BSU_24080" /old_locus_tag="BSU24080" /EC_number="1.4.1.8" /EC_number="1.4.1.-" /EC_number="1.4.1.9" /function="16.8: Protect" /function="16.2: Construct biomass (Anabolism)" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:4204435, 10094682, 12427936, 15241682, 20935095, 21856856, 22720735, 28165735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 4204435, 10094682, 12427936, 15241682, 20935095, 21856856, 22720735, 28165735; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="branched-chain amino acid dehydrogenase" /protein_id="NP_390288.1" /db_xref="EnsemblGenomes-Gn:BSU24080" /db_xref="EnsemblGenomes-Tr:CAB14339" /db_xref="GOA:P54531" /db_xref="InterPro:IPR006095" /db_xref="InterPro:IPR006096" /db_xref="InterPro:IPR006097" /db_xref="InterPro:IPR016211" /db_xref="InterPro:IPR033524" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG11723" /db_xref="UniProtKB/Swiss-Prot:P54531" /translation="MELFKYMEKYDYEQLVFCQDEQSGLKAIIAIHDTTLGPALGGTR MWTYENEEAAIEDALRLARGMTYKNAAAGLNLGGGKTVIIGDPRKDKNEEMFRAFGRY IQGLNGRYITAEDVGTTVEDMDIIHDETDYVTGISPAFGSSGNPSPVTAYGVYRGMKA AAKAAFGTDSLEGKTIAVQGVGNVAYNLCRHLHEEGANLIVTDINKQSVQRAVEDFGA RAVDPDDIYSQDCDIYAPCALGATINDDTIKQLKAKVIAGAANNQLKETRHGDQIHEM GIVYAPDYVINAGGVINVADELYGYNAERALKKVEGIYGNIERVLEISQRDGIPAYLA ADRLAEERIERMRRSRSQFLQNGHSVLSRR*" gene complement(2368257..2369351) /gene="bcd" /locus_tag="BSU_24080" /old_locus_tag="BSU24080" CDS complement(2369363..2370262) /gene="ptb" /locus_tag="BSU_24090" /old_locus_tag="BSU24090" /EC_number="2.3.1.19" /EC_number="2.3.1.-" /function="16.2: Construct biomass (Anabolism)" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:10094682, 12427936, 15241682, 22720735, 28165735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10094682, 12427936, 15241682, 22720735, 28165735; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="phosphate BCFA and butyryl coenzyme A transferase" /protein_id="NP_390289.2" /db_xref="EnsemblGenomes-Gn:BSU24090" /db_xref="EnsemblGenomes-Tr:CAB14340" /db_xref="GOA:P54530" /db_xref="InterPro:IPR002505" /db_xref="InterPro:IPR012147" /db_xref="InterPro:IPR014079" /db_xref="SubtiList:BG11722" /db_xref="UniProtKB/Swiss-Prot:P54530" /translation="MKLKDLIGKASIHKNKTIAVAHAEDEEVIRAVKLAAEHLSARFL LTGDSKKLNELTSSMQGHQVEIVHANTPEESAKLAVRAVHHKTADVLMKGNVPTSVLL KAVLNRQEGLRSASVLSHVAVFDIPDFDRLMFVTDSAMNIAPSLEELRQILQNAVHVA HAVGNNMPKAAALAAVETVNPKMEATVNAAALAQMYKRGQIKGCIVDGPLALDNAVSQ IAAAQKKISGDVAGNADILLVPTIEAGNILYKSLIYFAKASVAAVITGAKAPIALTSR ADSAENKLYSIALAICASEEYTH*" gene complement(2369363..2370262) /gene="ptb" /locus_tag="BSU_24090" /old_locus_tag="BSU24090" misc_feature complement(2370298..2370317) /Source="Nicolas_upshift_promotors" /id="U1878" /multdbtbs="SigL" /comp="M18" /sig="SigL" /pcomp="0.764235764235764" /psig="0.764235764235764" /xcortree=340 /SigmaFactorBS="tgcacgaatgtttcggtatacctggtatgacagcacccttaa gagcTGGCATGGAACTTGCATAATaaaaggcggagtcgaaacaagaaaggtggtaaca g" /listShort="ptb, bcd, buk, lpdV, bkdAA, bkdAB, bkdB" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(2370303) /Source="Nicolas_upshifts" /id="U1878" /multdbtbs="SigL" /comp="M18" /sig="SigL" /pcomp="0.764235764235764" /psig="0.764235764235764" /xcortree=340 /SigmaFactorBS="tgcacgaatgtttcggtatacctggtatgacagcacccttaa gagcTGGCATGGAACTTGCATAATaaaaggcggagtcgaaacaagaaaggtggtaaca g" /listShort="ptb, bcd, buk, lpdV, bkdAA, bkdAB, bkdB" /GFF_Attribute="listLong" S_feature complement(2370305..2370386) /Source="Nicolas_S_feature" /locus_tag="new_2504707_2504788_c" /HighExp="Cold, LBGtran, G180, Lbexp, G135, G150, LBGexp, Diami, Oxctl, Mt0" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S910" CDS complement(2370387..2372465) /gene="bkdR" /locus_tag="BSU_24100" /old_locus_tag="BSU24100" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:10094682, 12427936, 15241682, 16585774" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10094682, 12427936, 15241682, 16585774; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator" /protein_id="NP_390290.1" /db_xref="EnsemblGenomes-Gn:BSU24100" /db_xref="EnsemblGenomes-Tr:CAB14341" /db_xref="GOA:P54529" /db_xref="InterPro:IPR000014" /db_xref="InterPro:IPR002078" /db_xref="InterPro:IPR002197" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR009057" /db_xref="InterPro:IPR013767" /db_xref="InterPro:IPR025662" /db_xref="InterPro:IPR025943" /db_xref="InterPro:IPR025944" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR035965" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG11721" /db_xref="UniProtKB/Swiss-Prot:P54529" /translation="MQKVLIVGAGKRGTALLHILIKTAIIDIIAVVDKDPEAPGLKEA EQYGIAVSSDWKPYIQQKPDIVIHTTGDQAVFDELLQRKHEDTIVMPGKMAYIVFQLM EEKQHLIQMLKEQTYKYDRIFNSTHDGMIFIDINEEIILFNHMAEKMVGKKREEVIGR PIKEVIPSTKMPRILKTRVPEYNQKQLLGDHLQIVTTRLPIIDEGGRLLGALCVFKDI TDAVELAEEVTNLKQVRTMLEAIIQSSDEAISVVDENGIGLLINKAYTKMTGLSEKEV IGKPANTDISEGESMHLKVLETRRPVRGVRMKVGPNEKEVIVNVAPVIVDGILKGSVG VIHDVSEIKMLTAELNRARQIIRTLEAKYTFDDIIGKSEQMLVALEQAKLGAKTPATI LLRGESGTGKELFAHAIHNESDRKYNKFIRVNCAALSENLLESELFGYEDGAFSGAKR GGKKGLFEEANNGSIFLDEIGELTQNMQAKLLRVLQEKEIVRVGGTKAIPVNVRVIAA TNVNIEKAMADGTFREDLYYRINRYPISIPPLRQRLEDIEALSVRLIQKINRDYGRNV KGLSQQALRALSAYHWPGNVRELENVLGRAMIFLNPHMEWIEKDHLPVFELEQKENDT DQGTGFDFPDIEGEKLSVAVEKFEAHLIQQTLEKHHFNRTKTAKALGVSIRNLYYKMD KYGLANEGMQ*" gene complement(2370387..2372465) /gene="bkdR" /locus_tag="BSU_24100" /old_locus_tag="BSU24100" promotor_-10 complement(2372525..2372544) /Source="Nicolas_upshift_promotors" /id="U1879" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.949050949050949" /psig=1 /xcortree=2683 /SigmaFactorBS="ttatcttttcatttcctttattgtccagcggaaaaaatATTT tgtcaagagaagaaaaCGTGGTAACATAGGGTTGTGcaaattattgcaacggaataaa t" /listShort="bkdR, S910, ptb, bcd, buk, lpdV, bkdAA, bkdAB, bkdB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2372542) /Source="Nicolas_upshifts" /id="U1879" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.949050949050949" /psig=1 /xcortree=2683 /SigmaFactorBS="ttatcttttcatttcctttattgtccagcggaaaaaatATTT tgtcaagagaagaaaaCGTGGTAACATAGGGTTGTGcaaattattgcaacggaataaa t" /listShort="bkdR, S910, ptb, bcd, buk, lpdV, bkdAA, bkdAB, bkdB" /GFF_Attribute="listLong" promotor_-35 2372552..2372559 /Source="Nicolas_upshift_promotors" /id="U1880" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.63036963036963" /psig="0.998001998001998" /xcortree=386 /SigmaFactorBS="atttgcacaaccctatgttaccacgttttcttCTCTTGACaa aatattttttcCGCTGGACAATAAAGGAAATgaaaagataaaggggttttctgaagat g" /listShort="yqzF" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 complement(2372561..2372564) /Source="Nicolas_upshift_promotors" /id="U1879" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.949050949050949" /psig=1 /xcortree=2683 /SigmaFactorBS="ttatcttttcatttcctttattgtccagcggaaaaaatATTT tgtcaagagaagaaaaCGTGGTAACATAGGGTTGTGcaaattattgcaacggaataaa t" /listShort="bkdR, S910, ptb, bcd, buk, lpdV, bkdAA, bkdAB, bkdB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2372573..2372592 /Source="Nicolas_upshift_promotors" /id="U1880" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.63036963036963" /psig="0.998001998001998" /xcortree=386 /SigmaFactorBS="atttgcacaaccctatgttaccacgttttcttCTCTTGACaa aatattttttcCGCTGGACAATAAAGGAAATgaaaagataaaggggttttctgaagat g" /listShort="yqzF" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2372580 /Source="Nicolas_upshifts" /id="U1880" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.63036963036963" /psig="0.998001998001998" /xcortree=386 /SigmaFactorBS="atttgcacaaccctatgttaccacgttttcttCTCTTGACaa aatattttttcCGCTGGACAATAAAGGAAATgaaaagataaaggggttttctgaagat g" /listShort="yqzF" /GFF_Attribute="listLong" CDS 2372618..2372854 /gene="yqzF" /locus_tag="BSU_24110" /old_locus_tag="BSU24110" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_390291.1" /db_xref="EnsemblGenomes-Gn:BSU24110" /db_xref="EnsemblGenomes-Tr:CAB14342" /db_xref="GOA:O32015" /db_xref="InterPro:IPR020138" /db_xref="SubtiList:BG13772" /db_xref="UniProtKB/Swiss-Prot:O32015" /translation="MSRLLALLILVIPGAISALGIKLMRDTLFGHTIKPFSALWLQGL SGFIFFAIGLYVLAGFILYRDRKRNQVSPRFRKR*" gene 2372618..2372854 /gene="yqzF" /locus_tag="BSU_24110" /old_locus_tag="BSU24110" downshifts 2372845 /Source="Nicolas_upshifts" /id="D1259" /incds=0 /nref=64 /ntot=230 /MaxReadThrough="2.80342" /MaxDrop="5.10794" /score="42.7247617" /energy="-11.9" /TU="NA" /idTUdmin="U1880" /TUdmin=0 /isTUend="TRUE" CDS complement(2372896..2373801) /gene="mmgF" /locus_tag="BSU_24120" /old_locus_tag="BSU24120" /EC_number="4.1.3.30" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:12706720, 17274076, 28956599" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12706720, 17274076, 28956599; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="2-methylisocitrate lyase" /protein_id="NP_390292.1" /db_xref="EnsemblGenomes-Gn:BSU24120" /db_xref="EnsemblGenomes-Tr:CAB14343" /db_xref="GOA:P54528" /db_xref="InterPro:IPR012695" /db_xref="InterPro:IPR015813" /db_xref="InterPro:IPR018523" /db_xref="SubtiList:BG11720" /db_xref="UniProtKB/Swiss-Prot:P54528" /translation="MSWIVNKQSSQEELAGRFRKLMSAPDILQIPGAHDGMAALLAKE AGFSAIYLSGAAYTASRGLPDLGIITSAEIAERAKDLVRAADLPLLVDIDTGFGGVLN AARTAREMLEARVAAVQMEDQQLPKKCGHLNGKQLVPIKEMAQKIKAIKQAAPSLIVV ARTDARAQEGLDAAIKRSEAYIEAGADAIFPEALQAENEFRQFAERIPVPLLANMTEF GKTPYYRADEFEDMGFHMVIYPVTSLRAAAKACERMFGLMKEHGSQKEGLHDMQTRKE LYDTISYYDYEALDKTIAKTVLPDE*" gene complement(2372896..2373801) /gene="mmgF" /locus_tag="BSU_24120" /old_locus_tag="BSU24120" downshifts complement(2372899) /Source="Nicolas_upshifts" /id="D1260" /incds=0 /nref=29 /ntot=69 /MaxReadThrough="2.12559" /MaxDrop="5.62" /score="33.814061" /energy="-11.9" /TU="NA" /idTUdmin="U1884" /TUdmin=0 /isTUend="TRUE" CDS complement(2373819..2375237) /gene="mmgE" /locus_tag="BSU_24130" /old_locus_tag="BSU24130" /EC_number="4.2.1.79" /EC_number="4.2.1.-" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:17274076, 28956599" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 17274076, 28956599; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="2-methylcitrate dehydratase (promiscuous)" /protein_id="NP_390293.2" /db_xref="EnsemblGenomes-Gn:BSU24130" /db_xref="EnsemblGenomes-Tr:CAB14344" /db_xref="GOA:P45859" /db_xref="InterPro:IPR005656" /db_xref="InterPro:IPR012705" /db_xref="InterPro:IPR036148" /db_xref="SubtiList:BG11323" /db_xref="UniProtKB/Swiss-Prot:P45859" /translation="MPKTDRVIEEITDYVLEKEITSAEAYTTAGHVLLDTLGCGILAL RYPECTKLLGPIVPGTTVPNGSKVPGTSYVLDPVRAAFNIGCMIRWLDYNDTWLAAEW GHPSDNLGGILAAADYVSRVRLSEGKEPLTVRDVLEMMIKAHEIQGVLALENSLNRVG LDHVLFVKVATTAVAAKLLGGGREEIKNALSNAWIDNAALRTYRHSPNTGSRKSWAAG DATSRGVHLALMSLKGEMGYPTALSAPGWGFQDVLFNKKEIKLARPLDAYVMENVLFK VSYPAEFHAQTAAESAVILHPQVKNRIDEIDRVVIRTHESAIRIIDKKGPLHNPADRD HCLQYITAIGLLFGDITAQHYEAETANDPRIDKLRDKMEVTENKTYTEDYLKPDKRSI SNAVQVHFKDGTSTEMVECEFPLGHRFRREEAVPKLLEKFSDNLKTHFPDKQHKHIYE RCTSYETLQTMRVNEFVDMFCM*" gene complement(2373819..2375237) /gene="mmgE" /locus_tag="BSU_24130" /old_locus_tag="BSU24130" misc_feature complement(2374114..2374133) /Source="Nicolas_upshift_promotors" /id="U1881" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.881118881118881" /psig="0.997002997002997" /xcortree=616 /SigmaFactorBS="tatcaccgcacagcattatgaagctgaaacagcgaatgatcc gagaatagataaacttCGTGATAAAATGGAAGTGACtgaaaataaaacatataccgag g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(2374131) /Source="Nicolas_upshifts" /id="U1881" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.881118881118881" /psig="0.997002997002997" /xcortree=616 /SigmaFactorBS="tatcaccgcacagcattatgaagctgaaacagcgaatgatcc gagaatagataaacttCGTGATAAAATGGAAGTGACtgaaaataaaacatataccgag g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" CDS complement(2375252..2376370) /gene="mmgD" /locus_tag="BSU_24140" /old_locus_tag="BSU24140" /EC_number="2.3.3.5" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:8759838, 17274076, 28956599" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8759838, 17274076, 28956599; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="bifunctional citrate synthase/2-methylcitrate synthase" /protein_id="NP_390294.1" /db_xref="EnsemblGenomes-Gn:BSU24140" /db_xref="EnsemblGenomes-Tr:CAB14345" /db_xref="GOA:P45858" /db_xref="InterPro:IPR002020" /db_xref="InterPro:IPR016142" /db_xref="InterPro:IPR019810" /db_xref="InterPro:IPR024176" /db_xref="InterPro:IPR036969" /db_xref="SubtiList:BG11322" /db_xref="UniProtKB/Swiss-Prot:P45858" /translation="MEEKQHYSPGLDGVIAAETHISYLDTQSSQILIRGYDLIELSET KSYLELVHLLLEGRLPEESEMETLERKINSASSLPADHLRLLELLPEDTHPMDGLRTG LSALAGYDRQIDDRSPSANKERAYQLLGKMPALTAASYRIINKKEPILPLQTLSYSAN FLYMMTGKLPSSLEEQIFDRSLVLYSEHEMPNSTFAARVIASTHSDLYGALTGAVASL KGNLHGGANEAVMYLLLEAKTTSDFEQLLQTKLKRKEKIMGFGHRVYMKKMDPRALMM KEALQQLCDKAGDHRLYEMCEAGERLMEKEKGLYPNLDYYAAPVYWMLGIPIPLYTPI FFSARTSGLCAHVIEQHANNRLFRPRVSYMGPRYQTKS*" gene complement(2375252..2376370) /gene="mmgD" /locus_tag="BSU_24140" /old_locus_tag="BSU24140" CDS complement(2376404..2377543) /gene="mmgC" /locus_tag="BSU_24150" /old_locus_tag="BSU24150" /EC_number="1.3.99.-" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:28956599" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 28956599; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="propionyl-CoA dehydrogenase subunit" /protein_id="NP_390295.2" /db_xref="EnsemblGenomes-Gn:BSU24150" /db_xref="EnsemblGenomes-Tr:CAB14346" /db_xref="GOA:P45857" /db_xref="InterPro:IPR006089" /db_xref="InterPro:IPR006091" /db_xref="InterPro:IPR009075" /db_xref="InterPro:IPR009100" /db_xref="InterPro:IPR013786" /db_xref="InterPro:IPR036250" /db_xref="InterPro:IPR037069" /db_xref="PDB:5LNX" /db_xref="SubtiList:BG11321" /db_xref="UniProtKB/Swiss-Prot:P45857" /translation="MHVTQEQVMMRKMVRDFARKEIAPAAEIMEKTDEFPFQLIKKMG KHGLMGIPVPEQYGGAGADVVSYILAIHEISRISAAVGVILSVHTSVGTNPILYFGNE EQKMKYIPNLASGDHLGAFALTEPHSGSDAGSLRTTAIKKNGKYLLNGSKIFITNGGA ADIYITFALTAPDQGRHGISAFIVEKNTPGFTVGKKERKLGLYGSNTTELIFDNAEVP EANLLGKEGDGFHIAMANLNVGRIGIAAQALGIAEAALEHAVDYAKQRVQFGRPIAAN QGISFKLADMATRAEAARHLVYHAADLHNRGLNCGKEASMAKQFASDAAVKAALDAVQ IYGGYGYMKDYPVERLLRDAKVTQIYEGTNEIQRLIISKYLLGGT*" gene complement(2376404..2377543) /gene="mmgC" /locus_tag="BSU_24150" /old_locus_tag="BSU24150" CDS complement(2377571..2378434) /gene="mmgB" /locus_tag="BSU_24160" /old_locus_tag="BSU24160" /EC_number="1.1.1.157" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:8759838, 18461320, 28956599" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8759838, 18461320, 28956599; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="3-hydroxybutyryl-CoA dehydrogenase" /protein_id="NP_390296.2" /db_xref="EnsemblGenomes-Gn:BSU24160" /db_xref="EnsemblGenomes-Tr:CAB14347" /db_xref="GOA:P45856" /db_xref="InterPro:IPR006108" /db_xref="InterPro:IPR006176" /db_xref="InterPro:IPR006180" /db_xref="InterPro:IPR008927" /db_xref="InterPro:IPR013328" /db_xref="InterPro:IPR022694" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG11320" /db_xref="UniProtKB/Swiss-Prot:P45856" /translation="MEIKQIMVAGAGQMGSGIAQTAADAGFYVRMYDVNPEAAEAGLK RLKKQLARDAEKGKRTETEVKSVINRISISQTLEEAEHADIVIEAIAENMAAKTEMFK TLDRICPPHTILASNTSSLPITEIAAVTNRPQRVIGMHFMNPVPVMKLVEVIRGLATS EETALDVMALAEKMGKTAVEVNDFPGFVSNRVLLPMINEAIYCVYEGVAKPEAIDEVM KLGMNHPMGPLALADFIGLDTCLSIMEVLHSGLGDSKYRPCPLLRKYVKAGWLGKKSG RGFYDYEEKTS*" gene complement(2377571..2378434) /gene="mmgB" /locus_tag="BSU_24160" /old_locus_tag="BSU24160" CDS complement(2378459..2379640) /gene="mmgA" /locus_tag="BSU_24170" /old_locus_tag="BSU24170" /EC_number="2.3.1.9" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:16352833, 18246303, 19016856, 28956599" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16352833, 18246303, 19016856, 28956599; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="degradative acetoacetyl-CoA thiolase" /protein_id="NP_390297.1" /db_xref="EnsemblGenomes-Gn:BSU24170" /db_xref="EnsemblGenomes-Tr:CAB14348" /db_xref="GOA:P45855" /db_xref="InterPro:IPR002155" /db_xref="InterPro:IPR016039" /db_xref="InterPro:IPR020610" /db_xref="InterPro:IPR020613" /db_xref="InterPro:IPR020615" /db_xref="InterPro:IPR020616" /db_xref="InterPro:IPR020617" /db_xref="PDB:5LP7" /db_xref="SubtiList:BG11319" /db_xref="UniProtKB/Swiss-Prot:P45855" /translation="MRKTVIVSAARTPFGKFGGVLKEVKAAELGGIVMKEALQQAGVS GDDVEGNVMGMVVQAGSGQIPSRQAARLAGMPWSVPSETLNKVCASGLRAVTLCDQMI RAQDADILVAGGMESMSNIPYAVPAGRWGARMGDGELRDLMVYDGLTCAFDEVHMAVH GNTAAKEYAISRREQDEWALRSHARAAKAADEGKFQDEIVPVNWIGRKGKPNVVDKDE AIRRDTSLDQLAKLAPIYASDGSITAGNAPGVNDGAGAFVLMSEEKAAELGKRPLATI LGFSTTGMPAHELAAAPGFAINKLLKKNGLTVQDIDLFEVNEAFASVVLTCEKIVGFD LEKVNVNGGAIALGHPIGASGARILMTLVYELKRRGGGLGVAAICSGAAQGDAVLVQV H*" gene complement(2378459..2379640) /gene="mmgA" /locus_tag="BSU_24170" /old_locus_tag="BSU24170" downshifts complement(2379220) /Source="Nicolas_upshifts" /id="D1261" /incds=1 /nref=1 /ntot=1 /MaxReadThrough="6.17207" /MaxDrop="2.33167" /score="-0.949614429" /energy="-7.8" /TU="U1884" /idTUdmin="U1885" /TUdmin=550 /isTUend="FALSE" misc_feature complement(2379327..2379333) /Source="Nicolas_upshift_promotors" /id="U1882" /multdbtbs="-" /comp="M20" /sig="Sig-" /pcomp="0.382617382617383" /psig="0.0869130869130869" /xcortree=1497 /SigmaFactorBS="tgaataaagtctgtgcttccggccttcgcgctgtcactttat gtgatcaaatgattcGGGCGCAggatgcggacatacttgttgcgggggggatggaaag c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(2379330) /Source="Nicolas_upshifts" /id="U1882" /multdbtbs="-" /comp="M20" /sig="Sig-" /pcomp="0.382617382617383" /psig="0.0869130869130869" /xcortree=1497 /SigmaFactorBS="tgaataaagtctgtgcttccggccttcgcgctgtcactttat gtgatcaaatgattcGGGCGCAggatgcggacatacttgttgcgggggggatggaaag c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_no_box complement(2379554..2379654) /Source="Nicolas_upshift_promotors" /id="U1883" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.495504495504495" /psig="0.002997002997003" /xcortree=1483 /SigmaFactorBS="aatgaggtgaaaccatgaggaaaacagtcattgtaagtgctg caagaactccatttggcaaattcggcggagttttgaaagaggtgaaagctgctgagct t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_no_box" upshifts complement(2379594) /Source="Nicolas_upshifts" /id="U1883" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.495504495504495" /psig="0.002997002997003" /xcortree=1483 /SigmaFactorBS="aatgaggtgaaaccatgaggaaaacagtcattgtaagtgctg caagaactccatttggcaaattcggcggagttttgaaagaggtgaaagctgctgagct t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 complement(2379687..2379705) /Source="Nicolas_upshift_promotors" /id="U1884" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1050 /SigmaFactorBS="tgttagaaggaggctgtttgacgcagccttcttttttcaTTC ATTcatgcccgtttcaaaGCATACATTCATAGAAGACaactagaaattgtaagcgctg t" /listShort="mmgA, mmgB, mmgC, prpC, prpD, prpB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2379705) /Source="Nicolas_upshifts" /id="U1884" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1050 /SigmaFactorBS="tgttagaaggaggctgtttgacgcagccttcttttttcaTTC ATTcatgcccgtttcaaaGCATACATTCATAGAAGACaactagaaattgtaagcgctg t" /listShort="mmgA, mmgB, mmgC, prpC, prpD, prpB" /GFF_Attribute="listLong" promotor_-35 complement(2379721..2379726) /Source="Nicolas_upshift_promotors" /id="U1884" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1050 /SigmaFactorBS="tgttagaaggaggctgtttgacgcagccttcttttttcaTTC ATTcatgcccgtttcaaaGCATACATTCATAGAAGACaactagaaattgtaagcgctg t" /listShort="mmgA, mmgB, mmgC, prpC, prpD, prpB" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2379767..2380498) /gene="glpQ" /locus_tag="BSU_24180" /old_locus_tag="BSU24180" /EC_number="3.1.4.46" /function="16.6: Maintain" /function="16.11: Scavenge (Catabolism)" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:6319195, 14563871, 21966272, 22843846, 24373430, 27780866" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 6319195, 14563871, 21966272, 22843846, 24373430, 27780866; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="glycerophosphodiester phosphodiesterase (exolytic cleavage of individual teichoic acid monomer units)" /protein_id="NP_390298.2" /db_xref="EnsemblGenomes-Gn:BSU24180" /db_xref="EnsemblGenomes-Tr:CAB14349" /db_xref="GOA:P54527" /db_xref="InterPro:IPR004129" /db_xref="InterPro:IPR017946" /db_xref="InterPro:IPR030395" /db_xref="SubtiList:BG11719" /db_xref="UniProtKB/Swiss-Prot:P54527" /translation="MTKIFAHRGASGQFPENTMLAFEKGIEAGADGIELDVQLTKDGR IVVIHDERLNRTTSLKGFVKDTAYDEVKTANAAAGHDQAYSDIKVPLLEDVLSWAVKK DFLINIELKNSVIRYEGMEEKVLEAVKRFNVEDRVILSTFNHDSLALCARLAPHIERA VLTSDVLYQADRYIASIPASGYHPKINSPGVTDEVLKKMRNGLIKVRPYTVNRPEDMK RLIEAGADGMFTDFPEKASALLKNE*" gene complement(2379767..2380498) /gene="glpQ" /locus_tag="BSU_24180" /old_locus_tag="BSU24180" downshifts complement(2379774) /Source="Nicolas_upshifts" /id="D1262" /incds=0 /nref=31 /ntot=180 /MaxReadThrough="0.31166" /MaxDrop="4.10202" /score="-0.949614429" /energy="-7.8" /TU="NA" /idTUdmin="U1885" /TUdmin="-4" /isTUend="TRUE" promotor_-10 complement(2380521..2380540) /Source="Nicolas_upshift_promotors" /id="U1885" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.838161838161838" /psig="0.999000999001" /xcortree=1960 /SigmaFactorBS="ttattatgatcagtagattgatacagccttaatcCTAGagtg gagccgacaaAATAAGTATAATGGAGAAAActttagggtttgaggtgaaacgatgaca a" /listShort="yqiK" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2380532) /Source="Nicolas_upshifts" /id="U1885" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.838161838161838" /psig="0.999000999001" /xcortree=1960 /SigmaFactorBS="ttattatgatcagtagattgatacagccttaatcCTAGagtg gagccgacaaAATAAGTATAATGGAGAAAActttagggtttgaggtgaaacgatgaca a" /listShort="yqiK" /GFF_Attribute="listLong" promotor_-35 complement(2380555..2380558) /Source="Nicolas_upshift_promotors" /id="U1885" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.838161838161838" /psig="0.999000999001" /xcortree=1960 /SigmaFactorBS="ttattatgatcagtagattgatacagccttaatcCTAGagtg gagccgacaaAATAAGTATAATGGAGAAAActttagggtttgaggtgaaacgatgaca a" /listShort="yqiK" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2380577..2381197) /gene="yqiI" /locus_tag="BSU_24190" /old_locus_tag="BSU24190" /EC_number="3.5.1.28" /experiment="publication(s) with functional evidences, PMID:22843846" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 22843846; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="N-acetylmuramoyl-L-alanine amidase" /protein_id="NP_390299.2" /db_xref="EnsemblGenomes-Gn:BSU24190" /db_xref="EnsemblGenomes-Tr:CAB14350" /db_xref="GOA:P54525" /db_xref="InterPro:IPR002508" /db_xref="SubtiList:BG11717" /db_xref="UniProtKB/Swiss-Prot:P54525" /translation="MRMLWRSLALCGLALTLAPCAQAAEPIEGKTVYIDAGHGGEDSG AVGNGLFEKDINLAVSEHVTDKLKEEGANPVASRSDDHFLTLEERVAKASANQADLFV SIHVNSGVASASGTETYFQSDYEGENSRRLASDIQSQLVSSLQTRDRGVKESDFYVIT YSQMPSVLAELGFITNSSDADKLGSEEYQQKAADAIVNGIDSYYDQ*" gene complement(2380577..2381197) /gene="yqiI" /locus_tag="BSU_24190" /old_locus_tag="BSU24190" CDS complement(2381212..2381505) /gene="yqiH" /locus_tag="BSU_24200" /old_locus_tag="BSU24200" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 22843846; Product type lp: lipoprotein" /codon_start=1 /transl_table=11 /product="putative lipoprotein" /protein_id="NP_390300.2" /db_xref="EnsemblGenomes-Gn:BSU24200" /db_xref="EnsemblGenomes-Tr:CAB14351" /db_xref="GOA:P40770" /db_xref="SubtiList:BG11030" /db_xref="UniProtKB/Swiss-Prot:P40770" /translation="MKQTVLLLFTALFLSGCSVASADDSVPRFTEEGKYIGSADPHTI AVSLNGEETMIQVPKDKRDECESLPDQTHVLVKYTKKDNGTLQLEDIQLRKNS*" gene complement(2381212..2381505) /gene="yqiH" /locus_tag="BSU_24200" /old_locus_tag="BSU24200" promotor_-10 complement(2381525..2381544) /Source="Nicolas_upshift_promotors" /id="U1886" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.909090909090909" /psig="0.978021978021978" /xcortree=2990 /SigmaFactorBS="aacttgctcgcctgcattcgcgttgTCTTTACAaattctcca ttctgGTCAAAGATAAAAGCCAAACatcaggaagaggtggtcatgtgaaacaaacggt t" /listShort="yqiH, yqiI, yqiK" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2381531) /Source="Nicolas_upshifts" /id="U1886" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.909090909090909" /psig="0.978021978021978" /xcortree=2990 /SigmaFactorBS="aacttgctcgcctgcattcgcgttgTCTTTACAaattctcca ttctgGTCAAAGATAAAAGCCAAACatcaggaagaggtggtcatgtgaaacaaacggt t" /listShort="yqiH, yqiI, yqiK" /GFF_Attribute="listLong" promotor_-35 complement(2381559..2381566) /Source="Nicolas_upshift_promotors" /id="U1886" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.909090909090909" /psig="0.978021978021978" /xcortree=2990 /SigmaFactorBS="aacttgctcgcctgcattcgcgttgTCTTTACAaattctcca ttctgGTCAAAGATAAAAGCCAAACatcaggaagaggtggtcatgtgaaacaaacggt t" /listShort="yqiH, yqiI, yqiK" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 2381761..2381768 /Source="Nicolas_upshift_promotors" /id="U1887" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.973026973026973" /psig="0.996003996003996" /xcortree=1968 /SigmaFactorBS="tttgagaatagggtgagcaaatCGTTTGACgggtgggtcagc cAAGCGTAACCTTTTAAAGGAtatttactttattgaaagaagttaaagccatgaaaaa a" /listShort="S911, yqiG" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2381782..2381801 /Source="Nicolas_upshift_promotors" /id="U1887" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.973026973026973" /psig="0.996003996003996" /xcortree=1968 /SigmaFactorBS="tttgagaatagggtgagcaaatCGTTTGACgggtgggtcagc cAAGCGTAACCTTTTAAAGGAtatttactttattgaaagaagttaaagccatgaaaaa a" /listShort="S911, yqiG" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 2381799..2382004 /Source="Nicolas_S_feature" /locus_tag="new_2516201_2516406" /HighExp="Diami, dia15, dia5, H2O2, Paraq, LBGexp, G180, LBGstat, LBGtran, G135" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.99653599999999998" /TUshortSig="SigA" /TUshortPSig="0.996" /TUlongSig="NA" /TUlongPSig="NA" /label="S911" upshifts 2381799 /Source="Nicolas_upshifts" /id="U1887" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.973026973026973" /psig="0.996003996003996" /xcortree=1968 /SigmaFactorBS="tttgagaatagggtgagcaaatCGTTTGACgggtgggtcagc cAAGCGTAACCTTTTAAAGGAtatttactttattgaaagaagttaaagccatgaaaaa a" /listShort="S911, yqiG" /GFF_Attribute="listLong" CDS 2381813..2381965 /locus_tag="BSU_24205" /old_locus_tag="BSU24205" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_009513977.1" /translation="MKEVKAMKKFVLLLAAAVITCSIGHQISGGYKGPEKERPKHHSA LKIFSR*" gene 2381813..2381965 /locus_tag="BSU_24205" /old_locus_tag="BSU24205" promotor_-35 2381973..2381980 /Source="Nicolas_upshift_promotors" /id="U1888" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.83016983016983" /psig="0.993006993006993" /xcortree=612 /SigmaFactorBS="tcaagatattcagtcggtaaagcagatCAATTGCAttaattt ttacataTAGGCTAGAATATGTGCGAAtccaaacgaaagaagatgatcaaatgaatcc t" /listShort="yqiG" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2381995..2382014 /Source="Nicolas_upshift_promotors" /id="U1888" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.83016983016983" /psig="0.993006993006993" /xcortree=612 /SigmaFactorBS="tcaagatattcagtcggtaaagcagatCAATTGCAttaattt ttacataTAGGCTAGAATATGTGCGAAtccaaacgaaagaagatgatcaaatgaatcc t" /listShort="yqiG" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2382006 /Source="Nicolas_upshifts" /id="U1888" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.83016983016983" /psig="0.993006993006993" /xcortree=612 /SigmaFactorBS="tcaagatattcagtcggtaaagcagatCAATTGCAttaattt ttacataTAGGCTAGAATATGTGCGAAtccaaacgaaagaagatgatcaaatgaatcc t" /listShort="yqiG" /GFF_Attribute="listLong" CDS 2382038..2383156 /gene="yqiG" /locus_tag="BSU_24210" /old_locus_tag="BSU24210" /EC_number="1.-.-.-" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 25355936; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative NADH-dependent flavin oxidoreductase" /protein_id="NP_390301.1" /db_xref="EnsemblGenomes-Gn:BSU24210" /db_xref="EnsemblGenomes-Tr:CAB14352" /db_xref="GOA:P54524" /db_xref="InterPro:IPR001155" /db_xref="InterPro:IPR013785" /db_xref="SubtiList:BG11716" /db_xref="UniProtKB/Swiss-Prot:P54524" /translation="MNPKYKPLFEPFTFKSGVTINNRIAVAPMTHYASNEDGTISEAE LDYIIPRSKEMGMVITACANVTPDGKAFPGQPAIHDDSNIPGLKKLAQAIQAQGAKAV VQIHHGGIECPSELVPQQDVVGPSDVFDNGKQIARALTEEEVENIVKAFGEATRRAIE AGFDGVEIHGANGYLIQQFYSPKTNQRTDRWGGSDEKRLAFPLAIVDEVKKAASEHAK GAFLVGYRLSPEEPETPGLTMTETYTLVDALGDKELDYLHISLMDVNSKARRGADPTR TRMDLLNERVGNKVPLIAVGSIHSADDALAVIENGIPLVAMGREILVDPNWTVKVKEG REKQIETVIKGTDKEKYHLPEPLWQAIVNTQGWVPYKD*" gene 2382038..2383156 /gene="yqiG" /locus_tag="BSU_24210" /old_locus_tag="BSU24210" downshifts 2383141 /Source="Nicolas_upshifts" /id="D1263" /incds=0 /nref=23 /ntot=181 /MaxReadThrough="1.88324" /MaxDrop="6.67511" /score="30.8551972" /energy="-16.1" /TU="NA" /idTUdmin="U1887" /TUdmin="-9" /isTUend="TRUE" S_feature complement(2383183..2383353) /Source="Nicolas_S_feature" /locus_tag="new_2517585_2517755_c" /HighExp="T0.30H, S6, S8, T1.30H, T1.0H, T-0.40H, S7, Salt, T0.0H, T2.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigWXY, SigK" /TUshortPSig="1, 0.956" /TUlongSig="NA" /TUlongPSig="NA" /label="S912" downshifts complement(2383226) /Source="Nicolas_upshifts" /id="D1264" /incds=0 /nref=1 /ntot=37 /MaxReadThrough="3.46085" /MaxDrop="2.69939" /score="-5.47428449" /energy="-16.1" /TU="U1889" /idTUdmin="U1890" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(2383337..2383352) /Source="Nicolas_upshift_promotors" /id="U1889" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1662 /SigmaFactorBS="tcacgaagcatgatcgaccctagatgtgtccgttataaaaTG AAACCTTTctcctgcaaaaTCGTAAGTAAGGCGTAttcatgtaaaaaggagacgtacg a" /listShort="S912" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2383353) /Source="Nicolas_upshifts" /id="U1889" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1662 /SigmaFactorBS="tcacgaagcatgatcgaccctagatgtgtccgttataaaaTG AAACCTTTctcctgcaaaaTCGTAAGTAAGGCGTAttcatgtaaaaaggagacgtacg a" /listShort="S912" /GFF_Attribute="listLong" S_feature complement(2383355..2383483) /Source="Nicolas_S_feature" /locus_tag="new_2517757_2517885_c" /HighExp="S6, S8, S7, S5, BT, M9-stat, B36, G180, G135, S4" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigK" /TUshortPSig="0.956" /TUlongSig="NA" /TUlongPSig="NA" /label="S913" promotor_-35 complement(2383364..2383373) /Source="Nicolas_upshift_promotors" /id="U1889" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1662 /SigmaFactorBS="tcacgaagcatgatcgaccctagatgtgtccgttataaaaTG AAACCTTTctcctgcaaaaTCGTAAGTAAGGCGTAttcatgtaaaaaggagacgtacg a" /listShort="S912" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(2383482..2383501) /Source="Nicolas_upshift_promotors" /id="U1890" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.956043956043956" /psig="0.956043956043956" /xcortree=1313 /SigmaFactorBS="ctgataaataggaggcgttttgttttggggacatttgtagta TGGGAGAAGaatattaagtatcCGCATATAGTAAAGGATAGGtttgaaaagtaaggaa a" /listShort="S913, S912" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2383505) /Source="Nicolas_upshifts" /id="U1890" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.956043956043956" /psig="0.956043956043956" /xcortree=1313 /SigmaFactorBS="ctgataaataggaggcgttttgttttggggacatttgtagta TGGGAGAAGaatattaagtatcCGCATATAGTAAAGGATAGGtttgaaaagtaaggaa a" /listShort="S913, S912" /GFF_Attribute="listLong" promotor_-35 complement(2383515..2383523) /Source="Nicolas_upshift_promotors" /id="U1890" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.956043956043956" /psig="0.956043956043956" /xcortree=1313 /SigmaFactorBS="ctgataaataggaggcgttttgttttggggacatttgtagta TGGGAGAAGaatattaagtatcCGCATATAGTAAAGGATAGGtttgaaaagtaaggaa a" /listShort="S913, S912" /GFF_Attribute="listLong" /label="promotor_-35" downshifts complement(2383615) /Source="Nicolas_upshifts" /id="D1265" /incds=0 /nref=199 /ntot=267 /MaxReadThrough="2.54843" /MaxDrop="4.82417" /score="-1.10791055" /energy="-15.5" /TU="NA" /idTUdmin="U1891" /TUdmin=0 /isTUend="TRUE" CDS complement(2383621..2384424) /gene="spo0A" /locus_tag="BSU_24220" /old_locus_tag="BSU24220" /function="16.12: Sense" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:8504245, 12406209, 15556029, 15808745, 23569226, 26152584, 27148245, 27501195, 28723971" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8504245, 12406209, 15556029, 15808745, 23569226, 26152584, 27148245, 27501195, 28723971; Product type r: regulator" /codon_start=1 /transl_table=11 /product="response regulator, phosphorylated in response to complex YlbF/YmcA/YaaT" /protein_id="NP_390302.1" /db_xref="EnsemblGenomes-Gn:BSU24220" /db_xref="EnsemblGenomes-Tr:CAB14353" /db_xref="GOA:P06534" /db_xref="InterPro:IPR001789" /db_xref="InterPro:IPR011006" /db_xref="InterPro:IPR012052" /db_xref="InterPro:IPR014879" /db_xref="InterPro:IPR016032" /db_xref="InterPro:IPR036388" /db_xref="PDB:1LQ1" /db_xref="SubtiList:BG10765" /db_xref="UniProtKB/Swiss-Prot:P06534" /translation="MEKIKVCVADDNRELVSLLSEYIEGQEDMEVIGVAYNGQECLSL FKEKDPDVLVLDIIMPHLDGLAVLERLRESDLKKQPNVIMLTAFGQEDVTKKAVDLGA SYFILKPFDMENLVGHIRQVSGNASSVTHRAPSSQSSIIRSSQPEPKKKNLDASITSI IHEIGVPAHIKGYLYLREAISMVYNDIELLGSITKVLYPDIAKKFNTTASRVERAIRH AIEVAWSRGNIDSISSLFGYTVSMTKAKPTNSEFIAMVADKLRLEHKAS*" gene complement(2383621..2384424) /gene="spo0A" /locus_tag="BSU_24220" /old_locus_tag="BSU24220" promotor_-10 complement(2384467..2384485) /Source="Nicolas_upshift_promotors" /id="U1891" /multdbtbs="SigH" /comp="M1" /sig="SigH" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=457 /SigmaFactorBS="ccactaatattggtgattatgatttttttAGAGGGTATatag cggtttTGTCGAATGTAAACATGTAgcaagggtgaatcctgttaactacatttgggga g" /listShort="spo0A" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2384473) /Source="Nicolas_upshifts" /id="U1891" /multdbtbs="SigH" /comp="M1" /sig="SigH" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=457 /SigmaFactorBS="ccactaatattggtgattatgatttttttAGAGGGTATatag cggtttTGTCGAATGTAAACATGTAgcaagggtgaatcctgttaactacatttgggga g" /listShort="spo0A" /GFF_Attribute="listLong" S_feature complement(2384475..2384627) /Source="Nicolas_S_feature" /locus_tag="new_2518877_2519029_c" /HighExp="T1.30H, T3.0H, T2.30H, T2.0H, HiTm, Lbtran, T1.0H, T-0.40H, T0.30H, T-1.10H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S914" promotor_-35 complement(2384496..2384504) /Source="Nicolas_upshift_promotors" /id="U1891" /multdbtbs="SigH" /comp="M1" /sig="SigH" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=457 /SigmaFactorBS="ccactaatattggtgattatgatttttttAGAGGGTATatag cggtttTGTCGAATGTAAACATGTAgcaagggtgaatcctgttaactacatttgggga g" /listShort="spo0A" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(2384623..2384642) /Source="Nicolas_upshift_promotors" /id="U1892" /multdbtbs="SigA,SigA" /comp="M4" /sig="SigA" /pcomp="0.703296703296703" /psig=1 /xcortree=2278 /SigmaFactorBS="cggagtttccggcagtttttttattttgatccctCTTCACTT ctcagaatacaTACGGTAAAATATACAAAAGaagatttttcgacaaattcacgtttcc t" /listShort="S914, spo0A" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2384635) /Source="Nicolas_upshifts" /id="U1892" /multdbtbs="SigA,SigA" /comp="M4" /sig="SigA" /pcomp="0.703296703296703" /psig=1 /xcortree=2278 /SigmaFactorBS="cggagtttccggcagtttttttattttgatccctCTTCACTT ctcagaatacaTACGGTAAAATATACAAAAGaagatttttcgacaaattcacgtttcc t" /listShort="S914, spo0A" /GFF_Attribute="listLong" promotor_-35 complement(2384654..2384661) /Source="Nicolas_upshift_promotors" /id="U1892" /multdbtbs="SigA,SigA" /comp="M4" /sig="SigA" /pcomp="0.703296703296703" /psig=1 /xcortree=2278 /SigmaFactorBS="cggagtttccggcagtttttttattttgatccctCTTCACTT ctcagaatacaTACGGTAAAATATACAAAAGaagatttttcgacaaattcacgtttcc t" /listShort="S914, spo0A" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2384700..2385980) /gene="spoIVB" /locus_tag="BSU_24230" /old_locus_tag="BSU24230" /EC_number="3.4.-.-" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:12218026, 15292188, 16164552, 16238631, 16818230, 17493131, 17557826" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12218026, 15292188, 16164552, 16238631, 16818230, 17493131, 17557826; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="regulatory membrane-associated serine protease" /protein_id="NP_390303.2" /db_xref="EnsemblGenomes-Gn:BSU24230" /db_xref="EnsemblGenomes-Tr:CAB14354" /db_xref="GOA:P17896" /db_xref="InterPro:IPR001478" /db_xref="InterPro:IPR008763" /db_xref="InterPro:IPR009003" /db_xref="InterPro:IPR014219" /db_xref="InterPro:IPR036034" /db_xref="SubtiList:BG10311" /db_xref="UniProtKB/Swiss-Prot:P17896" /translation="MPDNIRKAVGLILLVSLLSVGLCKPLKEYLLIPTQMRVFETQTQ AIETSLSVNAQTSESSEAFTVKKDPHEIKVTGKKSGESELVYDLAGFPIKKTKVHVLP DLKVIPGGQSIGVKLHSVGVLVVGFHQINTSEGKKSPGETAGIEAGDIIIEMNGQKIE KMNDVAPFIQKAGKTGESLDLLIKRDKQKIKTKLIPEKDEGEGKYRIGLYIRDSAAGI GTMTFYEPKTKKYGALGHVISDMDTKKPIVVENGEIVKSTVTSIEKGTGGNPGEKLAR FSSERKTIGDINRNSPFGIFGTLHQPIQNNISDQALPVAFSTEVKKGPAEILTVIDDD KVEKFDIEIVSTTPQKFPATKGMVLKITDPRLLKETGGIVQGMSGSPIIQNGKVIGAV THVFVNDPTSGYGVHIEWMLSEAGIDIYGKEKAS*" gene complement(2384700..2385980) /gene="spoIVB" /locus_tag="BSU_24230" /old_locus_tag="BSU24230" downshifts complement(2384715) /Source="Nicolas_upshifts" /id="D1266" /incds=0 /nref=34 /ntot=51 /MaxReadThrough="1.04939" /MaxDrop="7.80695" /score="49.1812184" /energy="-12.5" /TU="NA" /idTUdmin="U1893" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(2386041..2386052) /Source="Nicolas_upshift_promotors" /id="U1893" /multdbtbs="SigF,SigG" /comp="M8" /sig="SigGF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=830 /SigmaFactorBS="cattcgttcatcagtatatccaatgtttttcttcatatgaca GTTATAAataagccgtcagaaGGCAAAATTAAAtgatgtagcagcaagtcataaagaa g" /listShort="spoIVB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2386055) /Source="Nicolas_upshifts" /id="U1893" /multdbtbs="SigF,SigG" /comp="M8" /sig="SigGF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=830 /SigmaFactorBS="cattcgttcatcagtatatccaatgtttttcttcatatgaca GTTATAAataagccgtcagaaGGCAAAATTAAAtgatgtagcagcaagtcataaagaa g" /listShort="spoIVB" /GFF_Attribute="listLong" promotor_-35 complement(2386067..2386073) /Source="Nicolas_upshift_promotors" /id="U1893" /multdbtbs="SigF,SigG" /comp="M8" /sig="SigGF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=830 /SigmaFactorBS="cattcgttcatcagtatatccaatgtttttcttcatatgaca GTTATAAataagccgtcagaaGGCAAAATTAAAtgatgtagcagcaagtcataaagaa g" /listShort="spoIVB" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2386155..2387885) /gene="recN" /locus_tag="BSU_24240" /old_locus_tag="BSU24240" /function="16.8: Protect" /function="16.6: Maintain" /function="16.9: Replicate" /experiment="publication(s) with functional evidences, PMID:15186413, 15849320, 15948952, 16009134, 16061691, 16385024, 17999999, 20360008, 21517913, 23380520, 24373815" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15186413, 15849320, 15948952, 16009134, 16061691, 16385024, 17999999, 20360008, 21517913, 23380520, 24373815; Product type f : factor" /codon_start=1 /transl_table=11 /product="factor for double strand breaks DNA repair and genetic recombination" /protein_id="NP_390304.2" /db_xref="EnsemblGenomes-Gn:BSU24240" /db_xref="EnsemblGenomes-Tr:CAB14355" /db_xref="GOA:P17894" /db_xref="InterPro:IPR004604" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG10310" /db_xref="UniProtKB/Swiss-Prot:P17894" /translation="MLAELSIKNFAIIEELTVSFERGLTVLTGETGAGKSIIIDAISL LVGGRGSSEFVRYGEAKAELEGLFLLESGHPVLGVCAEQGIDVSDEMIVMRRDISTSG KSVCRVNGKLVTIASLREIGRLLLDIHGQHDNQLLMEDENHLQLLDKFAGAEVESALK TYQEGYQRYVKLLKKLKQLSESEQEMAHRLDLIQFQLEEIESAKLELNEDEQLQEERQ QISNFEKIYESLQNAYNALRSEQGGLDWVGMASAQLEDISDINEPLKKMSESVSNSYY LLEDATFQMRNMLDELEFDPERLNYIETRLNEIKQLKRKYGATVEDILEYASKIEEEI DQIENRDSHLQSLKKELDSVGKDVAVEAANVSQIRKTWAKKLADEIHRELKSLYMEKS TFDTEFKVRTASRNEEAPLVNGQPVQLTEQGIDLVKFLISTNTGEPLKSLSKVASGGE LSRVMLAIKSIFSSQQDVTSIIFDEVDTGVSGRVAQAIAEKIHKVSIGSQVLCITHLP QVAAMADTHLYIAKELKDGRTTTRVKPLSKQEKVAEIGRMIAGVEVTDLTKRHAKELL KQADQVKTTG*" gene complement(2386155..2387885) /gene="recN" /locus_tag="BSU_24240" /old_locus_tag="BSU24240" downshifts complement(2386170) /Source="Nicolas_upshifts" /id="D1267" /incds=0 /nref=232 /ntot=260 /MaxReadThrough="1.73202" /MaxDrop="6.33427" /score="20.028822" /energy="-12.4" /TU="NA" /idTUdmin="U1895" /TUdmin=0 /isTUend="TRUE" CDS complement(2387922..2388371) /gene="argR" /locus_tag="BSU_24250" /old_locus_tag="BSU24250" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:180070, 9194709, 9383188, 11305941, 11856827, 17020585, 17576690, 18007040, 18455186" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 180070, 9194709, 9383188, 11305941, 11856827, 17020585, 17576690, 18007040, 18455186; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator (AhrC(ArgR)-arginine)" /protein_id="NP_390305.1" /db_xref="EnsemblGenomes-Gn:BSU24250" /db_xref="EnsemblGenomes-Tr:CAB14356" /db_xref="GOA:P17893" /db_xref="InterPro:IPR001669" /db_xref="InterPro:IPR020899" /db_xref="InterPro:IPR020900" /db_xref="InterPro:IPR024946" /db_xref="InterPro:IPR036251" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="PDB:1F9N" /db_xref="PDB:2P5K" /db_xref="PDB:2P5L" /db_xref="PDB:2P5M" /db_xref="SubtiList:BG10309" /db_xref="UniProtKB/Swiss-Prot:P17893" /translation="MNKGQRHIKIREIITSNEIETQDELVDMLKQDGYKVTQATVSRD IKELHLVKVPTNNGSYKYSLPADQRFNPLSKLKRALMDAFVKIDSASHMIVLKTMPGN AQAIGALMDNLDWDEMMGTICGDDTILIICRTPEDTEGVKNRLLELL*" gene complement(2387922..2388371) /gene="argR" /locus_tag="BSU_24250" /old_locus_tag="BSU24250" S_feature complement(2388372..2388457) /Source="Nicolas_S_feature" /locus_tag="new_2522774_2522859_c" /HighExp="H2O2, G180, G135, G150, Oxctl, Heat, Paraq, C30, dia15, LBGexp" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA, SigA" /TUshortPSig="0.999, 0.993, 1" /TUlongSig="SigB" /TUlongPSig="0.742" /label="S915" CDS complement(2388469..2389314) /gene="yqxC" /locus_tag="BSU_24260" /old_locus_tag="BSU24260" /EC_number="2.1.1.-" /function="9.4: RNA processing" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 16014871, 22333191, 24809820; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative 2'-O-ribose RNA methyltransferase" /protein_id="NP_390306.2" /db_xref="EnsemblGenomes-Gn:BSU24260" /db_xref="EnsemblGenomes-Tr:CAB14357" /db_xref="GOA:P19672" /db_xref="InterPro:IPR002877" /db_xref="InterPro:IPR002942" /db_xref="InterPro:IPR004538" /db_xref="InterPro:IPR029063" /db_xref="InterPro:IPR036986" /db_xref="SubtiList:BG10308" /db_xref="UniProtKB/Swiss-Prot:P19672" /translation="MTSKKERLDVLLVERGLAETREKAKRAIMAGIVYSNENRLDKPG EKIDRDLPLTVKGNPLRYVSRGGLKLEKALKEFPVSVKDKIMIDIGSSTGGFTDCALQ NGAKQSYAVDVGYNQLAWKLRQDERVVVMERTNFRYATPADFTKGMPEFATIDVSFIS LRLILPVLRTLLVPGSDCMALVKPQFEAGRESVGKKGIVRDPKVHADVLKRMISFSAA EGYICKGLSFSPITGGDGNIEFLLHLHWPGEGQEGQELPEEEIMRVVEEAHKTLKEKK ADVPE*" gene complement(2388469..2389314) /gene="yqxC" /locus_tag="BSU_24260" /old_locus_tag="BSU24260" downshifts complement(2388502) /Source="Nicolas_upshifts" /id="D1268" /incds=0 /nref=1 /ntot=65 /MaxReadThrough="5.65358" /MaxDrop="2.6955" /score="4.97422627" /energy="-9.4" /TU="U1895,U1896,U1898" /idTUdmin="U1895" /TUdmin="-2332" /isTUend="FALSE" CDS complement(2389311..2391212) /gene="dxs" /locus_tag="BSU_24270" /old_locus_tag="BSU24270" /EC_number="2.2.1.7" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 12682299, 12882400, 15292217, 17458547, 23840410, 25212876; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="1-deoxyxylulose-5-phosphate synthase" /protein_id="NP_390307.1" /db_xref="EnsemblGenomes-Gn:BSU24270" /db_xref="EnsemblGenomes-Tr:CAB14358" /db_xref="GOA:P54523" /db_xref="InterPro:IPR005474" /db_xref="InterPro:IPR005475" /db_xref="InterPro:IPR005477" /db_xref="InterPro:IPR009014" /db_xref="InterPro:IPR020826" /db_xref="InterPro:IPR029061" /db_xref="InterPro:IPR033248" /db_xref="SubtiList:BG11715" /db_xref="UniProtKB/Swiss-Prot:P54523" /translation="MDLLSIQDPSFLKNMSIDELEKLSDEIRQFLITSLSASGGHIGP NLGVVELTVALHKEFNSPKDKFLWDVGHQSYVHKLLTGRGKEFATLRQYKGLCGFPKR SESEHDVWETGHSSTSLSGAMGMAAARDIKGTDEYIIPIIGDGALTGGMALEALNHIG DEKKDMIVILNDNEMSIAPNVGAIHSMLGRLRTAGKYQWVKDELEYLFKKIPAVGGKL AATAERVKDSLKYMLVSGMFFEELGFTYLGPVDGHSYHELIENLQYAKKTKGPVLLHV ITKKGKGYKPAETDTIGTWHGTGPYKINTGDFVKPKAAAPSWSGLVSGTVQRMAREDG RIVAITPAMPVGSKLEGFAKEFPDRMFDVGIAEQHAATMAAAMAMQGMKPFLAIYSTF LQRAYDQVVHDICRQNANVFIGIDRAGLVGADGETHQGVFDIAFMRHIPNMVLMMPKD ENEGQHMVHTALSYDEGPIAMRFPRGNGLGVKMDEQLKTIPIGTWEVLRPGNDAVILT FGTTIEMAIEAAEELQKEGLSVRVVNARFIKPIDEKMMKSILKEGLPILTIEEAVLEG GFGSSILEFAHDQGEYHTPIDRMGIPDRFIEHGSVTALLEEIGLTKQQVANRIRLLMP PKTHKGIGS*" gene complement(2389311..2391212) /gene="dxs" /locus_tag="BSU_24270" /old_locus_tag="BSU24270" promotor_-35 2390420..2390426 /Source="Nicolas_upshift_promotors" /id="U1894" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=952 /SigmaFactorBS="tgcagaagaacagggcctttcgtttttttggCGTATTGaaga ttctcaatcaGCTCATGATAAGaatgtccgtccactgggcccaaatacgtaaaaccga g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2390441..2390452 /Source="Nicolas_upshift_promotors" /id="U1894" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=952 /SigmaFactorBS="tgcagaagaacagggcctttcgtttttttggCGTATTGaaga ttctcaatcaGCTCATGATAAGaatgtccgtccactgggcccaaatacgtaaaaccga g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2390449 /Source="Nicolas_upshifts" /id="U1894" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=952 /SigmaFactorBS="tgcagaagaacagggcctttcgtttttttggCGTATTGaaga ttctcaatcaGCTCATGATAAGaatgtccgtccactgggcccaaatacgtaaaaccga g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" S_feature complement(2391213..2391341) /Source="Nicolas_S_feature" /locus_tag="new_2525615_2525743_c" /HighExp="Salt, Heat, dia15, H2O2, HiOs, Cold, T-5.40H, T3.30H, SMM, G135" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA, SigA" /TUshortPSig="0.999, 0.993, 1" /TUlongSig="SigB" /TUlongPSig="0.742" /label="S916" promotor_-10 complement(2391336..2391355) /Source="Nicolas_upshift_promotors" /id="U1895" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.508491508491508" /psig="0.999000999001" /xcortree=2286 /SigmaFactorBS="gcaagagatcactaaaacgatcctaATTTGAAgcggctgcac gaggTATGGTAAAATGTAAGCAGTttatatgaaaaatgaaaaggaaaagcgcgtttgt c" /listShort="S916, dxs, yqxC, S915, ahrC, recN" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2391341) /Source="Nicolas_upshifts" /id="U1895" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.508491508491508" /psig="0.999000999001" /xcortree=2286 /SigmaFactorBS="gcaagagatcactaaaacgatcctaATTTGAAgcggctgcac gaggTATGGTAAAATGTAAGCAGTttatatgaaaaatgaaaaggaaaagcgcgtttgt c" /listShort="S916, dxs, yqxC, S915, ahrC, recN" /GFF_Attribute="listLong" promotor_-35 complement(2391370..2391376) /Source="Nicolas_upshift_promotors" /id="U1895" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.508491508491508" /psig="0.999000999001" /xcortree=2286 /SigmaFactorBS="gcaagagatcactaaaacgatcctaATTTGAAgcggctgcac gaggTATGGTAAAATGTAAGCAGTttatatgaaaaatgaaaaggaaaagcgcgtttgt c" /listShort="S916, dxs, yqxC, S915, ahrC, recN" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2391387..2392277) /gene="ispA" /locus_tag="BSU_24280" /old_locus_tag="BSU24280" /EC_number="2.5.1.10" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 8755734, 12682299, 17147392, 23569278; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="farnesyl diphosphate synthase" /protein_id="NP_390308.2" /db_xref="EnsemblGenomes-Gn:BSU24280" /db_xref="EnsemblGenomes-Tr:CAB14359" /db_xref="GOA:P54383" /db_xref="InterPro:IPR000092" /db_xref="InterPro:IPR008949" /db_xref="InterPro:IPR033749" /db_xref="SubtiList:BG11714" /db_xref="UniProtKB/Swiss-Prot:P54383" /translation="MTNKLTSFLADRKKTIENQLSVYTEKLDMPDSLKKSMLYSLQAG GKRLRPLIVLAVLNAYGKSEKDGIPVGCAVEMIHTYSLIHDDLPCMDDDDLRRGKPTN HKVFGEATAVLAGDGLLTESFKLITSHVSDEVSAEKRLRLVNELISAAGTEGMVGGQV ADMEAENRQVTLEELESIHERKTAKLLGFCVIAGAILADAPEEDIETLRTFSSHIGIG FQIRDDILDLEGSEEKIGKRVGSDTTNDKSTYPSLLSLEGAKHKLDVHIKEAKRLIGG LSLQKDLLYELCDLIAARDH*" gene complement(2391387..2392277) /gene="ispA" /locus_tag="BSU_24280" /old_locus_tag="BSU24280" CDS complement(2392267..2392521) /gene="xseB" /locus_tag="BSU_24290" /old_locus_tag="BSU24290" /EC_number="3.1.11.6" /function="16.6: Maintain" /function="16.9: Replicate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 11381137, 12682299; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="exodeoxyribonuclease VII (small subunit)" /protein_id="NP_390309.2" /db_xref="EnsemblGenomes-Gn:BSU24290" /db_xref="EnsemblGenomes-Tr:CAB14360" /db_xref="GOA:P54522" /db_xref="InterPro:IPR003761" /db_xref="InterPro:IPR037004" /db_xref="SubtiList:BG11713" /db_xref="UniProtKB/Swiss-Prot:P54522" /translation="MTDVKKNENMTFEEAMKGLESIVSKLEEGDVPLEQAINYFQEGM ALSKMCHEKLQKVEKQMDFILKEDGELAPFSVQEEDEGDK*" gene complement(2392267..2392521) /gene="xseB" /locus_tag="BSU_24290" /old_locus_tag="BSU24290" CDS complement(2392518..2393864) /gene="xseA" /locus_tag="BSU_24300" /old_locus_tag="BSU24300" /EC_number="3.1.11.6" /function="16.9: Replicate" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 12682299, 17182742; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="exodeoxyribonuclease VII (large subunit)" /protein_id="NP_390310.2" /db_xref="EnsemblGenomes-Gn:BSU24300" /db_xref="EnsemblGenomes-Tr:CAB14361" /db_xref="GOA:P54521" /db_xref="InterPro:IPR003753" /db_xref="InterPro:IPR020579" /db_xref="InterPro:IPR025824" /db_xref="SubtiList:BG11712" /db_xref="UniProtKB/Swiss-Prot:P54521" /translation="MGEAAYVTVSALTKYIKRKFDVDPHLENIWIKGELSNVKIHTRG HIYFTLKDENARMQSVMFARQSERLPFKPENGMKVLVRGGISVYEPSGNYQLYAKEMQ PDGVGALYLAYEELKKKLAGEGLFDDRYKKQIPAFPATIGVVTSPTGAAVRDVITTLK RRYPLVKVIVLPALVQGENASRSIVTRIEEANEKEICDVLIVGRGGGSIEELWAFNEE IVARAIFASNIPIISAVGHETDFTISDFVADIRAATPTGAAEIAVPHTTDLIERTKTA EVRMTRAMQQHLGQKKERIQTLQSSYAFRFPKRLYAQKEQQFDLAYQQFQAQLTALLD RKSRQLERETYRLEALHPHEQLKQARTRYQEQTNQLRKNMNIQMKQLHSQFQTVLGKL NALSPLQVMERGYSLAYKEDKLIKSVSQIEEQDRLEIKLKDGVLTCEVLEKRGEEK*" gene complement(2392518..2393864) /gene="xseA" /locus_tag="BSU_24300" /old_locus_tag="BSU24300" S_feature complement(2393865..2394001) /Source="Nicolas_S_feature" /locus_tag="new_2528267_2528403_c" /HighExp="H2O2, G180, G135, Cold, G150, Paraq, Oxctl, LBGstat, LPh, HPh" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigB, SigA" /TUshortPSig="0.993, 0.742, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S917" CDS complement(2394002..2394853) /gene="folD" /locus_tag="BSU_24310" /old_locus_tag="BSU24310" /EC_number="1.5.1.5" /EC_number="3.5.4.9" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 7061514, 9454603, 12682299, 19171795; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="methylenetetrahydrofolate dehydrogenase; methenyltetrahydrofolate cyclohydrolase" /protein_id="NP_390311.1" /db_xref="EnsemblGenomes-Gn:BSU24310" /db_xref="EnsemblGenomes-Tr:CAB14362" /db_xref="GOA:P54382" /db_xref="InterPro:IPR000672" /db_xref="InterPro:IPR020630" /db_xref="InterPro:IPR020631" /db_xref="InterPro:IPR020867" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG11711" /db_xref="UniProtKB/Swiss-Prot:P54382" /translation="MTATIIDGKETAREKREQLAKEVEELKKQGVTPGLAVILIGDDP ASHSYVRGKKKAAETMGMNFKLDQFDSSLTEAELLSIIDQYNQDPEFHGILVQLPLPD HISEKAVIERISPDKDVDGFHPLNVGKMLLGEDTFLPCTPHGIVELLKKTNIDLSGKE VVVVGRSNIVGKPVGQLLLNENATVTYCHSRTENITEHTKKADILVVAVGRANFISAD QIKEGAVVIDVGVNRLENGKLCGDVEFEGAKEKASFITPVPGGVGPMTITMLAHNTVK SAKRTLS*" gene complement(2394002..2394853) /gene="folD" /locus_tag="BSU_24310" /old_locus_tag="BSU24310" CDS complement(2394865..2395260) /gene="nusB" /locus_tag="BSU_24320" /old_locus_tag="BSU24320" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 16707701, 16946247, 27964882; Product type f: factor" /codon_start=1 /transl_table=11 /product="transcription termination factor NusB" /protein_id="NP_390312.2" /db_xref="EnsemblGenomes-Gn:BSU24320" /db_xref="EnsemblGenomes-Tr:CAB14363" /db_xref="GOA:P54520" /db_xref="InterPro:IPR006027" /db_xref="InterPro:IPR011605" /db_xref="InterPro:IPR035926" /db_xref="SubtiList:BG11710" /db_xref="UniProtKB/Swiss-Prot:P54520" /translation="MKRRTAREKALQALFQIDVSDIAVNEAIEHALDEEKTDPFFEQL VHGVLEHQDQLDEMISKHLVNWKLDRIANVDRAILRLAAYEMAYAEDIPVNVSMNEAI ELAKRFGDDKATKFVNGVLSNIKSDIEQS*" gene complement(2394865..2395260) /gene="nusB" /locus_tag="BSU_24320" /old_locus_tag="BSU24320" misc_feature complement(2395303..2395322) /Source="Nicolas_upshift_promotors" /id="U1896" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.416583416583417" /psig="0.993006993006993" /xcortree=2425 /SigmaFactorBS="tgaaaatattcggtaatagggtaaaaaaaccttgatttcaat atgcggatacgaaaaaaaTATGTTATGATCTCTTTGTGgcttaacgacaagcggataa a" /listShort="nusB, folD, S917, xseA, xseB, ispA, S916, dxs, yqxC, S915, ahrC, recN" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(2395322) /Source="Nicolas_upshifts" /id="U1896" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.416583416583417" /psig="0.993006993006993" /xcortree=2425 /SigmaFactorBS="tgaaaatattcggtaatagggtaaaaaaaccttgatttcaat atgcggatacgaaaaaaaTATGTTATGATCTCTTTGTGgcttaacgacaagcggataa a" /listShort="nusB, folD, S917, xseA, xseB, ispA, S916, dxs, yqxC, S915, ahrC, recN" /GFF_Attribute="listLong" S_feature complement(2395324..2395486) /Source="Nicolas_S_feature" /locus_tag="new_2529726_2529888_c" /HighExp="G180, G150, Oxctl, Etha, G135, GM 120, dia0, HPh, MG 150, LBGexp" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigB, SigA" /TUshortPSig="0.742, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S918" CDS complement(2395524..2395931) /gene="yqhY" /locus_tag="BSU_24330" /old_locus_tag="BSU24330" /function="16.13: Shape" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:16014871, 17114254, 22720735, 28579978" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16014871, 17114254, 22720735, 28579978; Product type ph: phenotype" /codon_start=1 /transl_table=11 /product="alkaline shock protein" /protein_id="NP_390313.2" /db_xref="EnsemblGenomes-Gn:BSU24330" /db_xref="EnsemblGenomes-Tr:CAB14364" /db_xref="InterPro:IPR005531" /db_xref="SubtiList:BG11709" /db_xref="UniProtKB/Swiss-Prot:P54519" /translation="MKDNSLLKMDHEDTHLGKVEIAPEVIEVIAGIAASEVDGVAEMR GNFATGVVERFGKVNHGKGVKVDLADDGITIDVYCVVTFGVSIPKVAASVQENIRQTL LNMTSLSINEINIHIVGIQFDTKAQEVQIDEEM*" gene complement(2395524..2395931) /gene="yqhY" /locus_tag="BSU_24330" /old_locus_tag="BSU24330" downshifts complement(2395531) /Source="Nicolas_upshifts" /id="D1269" /incds=0 /nref=6 /ntot=76 /MaxReadThrough="6.4099" /MaxDrop="4.1473" /score="9.44795832" /energy="-9.5" /TU="U1897,U1898" /idTUdmin="U1899" /TUdmin=2409 /isTUend="FALSE" CDS complement(2395952..2397304) /gene="accC" /locus_tag="BSU_24340" /old_locus_tag="BSU24340" /EC_number="6.3.4.14" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:7592499, 12682299, 14594796" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7592499, 12682299, 14594796; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="acetyl-CoA carboxylase subunit (biotin carboxylase subunit)" /protein_id="NP_390314.2" /db_xref="EnsemblGenomes-Gn:BSU24340" /db_xref="EnsemblGenomes-Tr:CAB14365" /db_xref="GOA:P49787" /db_xref="InterPro:IPR004549" /db_xref="InterPro:IPR005479" /db_xref="InterPro:IPR005481" /db_xref="InterPro:IPR005482" /db_xref="InterPro:IPR011054" /db_xref="InterPro:IPR011761" /db_xref="InterPro:IPR011764" /db_xref="InterPro:IPR013815" /db_xref="InterPro:IPR016185" /db_xref="SubtiList:BG11384" /db_xref="UniProtKB/Swiss-Prot:P49787" /translation="MIKKLLIANRGEIAVRIIRACRELGIETVAVYSEADKDALHVQM ADEAFCIGPKASKDSYLNVTNIVSVAKLTGTDAIHPGYGFLAENADFAELCEEVNVTF VGPSADAISKMGTKDVARETMKQAGVPIVPGSQGIIENVEEAVSLANEIGYPVIIKAT AGGGGKGIRVARTEEELINGIKITQQEAATAFGNPGVYIEKYIEDFRHVEIQVLADNY GNTIHLGERDCSIQRRLQKLLEESPSPALDSEIREQMGDAAVKAAKAVGYTGAGTVEF IYDYNEQRYYFMEMNTRIQVEHPVTEMVTGTDLIKEQIKVASGMELSLKQEDVEFEGW AIECRINAENPSKNFMPSPGEIKMYLPPGGLGVRVDSAAYPGYSIPPYYDSMIAKVIT YGKTRDEAIARMKRALSEFVIEGIETTIPFHLKLLEHETFVSGEFNTKFLETYDVMGS *" gene complement(2395952..2397304) /gene="accC" /locus_tag="BSU_24340" /old_locus_tag="BSU24340" promotor_-10 complement(2396833..2396852) /Source="Nicolas_upshift_promotors" /id="U1897" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.742257742257742" /psig="0.742257742257742" /xcortree=127 /SigmaFactorBS="gggaattatagaaaatgtggaagaagcGGTTTCGcttgctaa tgaaatTGGGTATCCTGTAATTATAAaagccaccgcaggcggaggcggaaaaggaatt a" /listShort="yqhY, S918, nusB, folD, S917, xseA, xseB, ispA" /listLong="S916, dxs, yqxC, S915, ahrC, recN" /label="promotor_-10" upshifts complement(2396840) /Source="Nicolas_upshifts" /id="U1897" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.742257742257742" /psig="0.742257742257742" /xcortree=127 /SigmaFactorBS="gggaattatagaaaatgtggaagaagcGGTTTCGcttgctaa tgaaatTGGGTATCCTGTAATTATAAaagccaccgcaggcggaggcggaaaaggaatt a" /listShort="yqhY, S918, nusB, folD, S917, xseA, xseB, ispA" /listLong="S916, dxs, yqxC, S915, ahrC, recN" promotor_-35 complement(2396867..2396873) /Source="Nicolas_upshift_promotors" /id="U1897" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.742257742257742" /psig="0.742257742257742" /xcortree=127 /SigmaFactorBS="gggaattatagaaaatgtggaagaagcGGTTTCGcttgctaa tgaaatTGGGTATCCTGTAATTATAAaagccaccgcaggcggaggcggaaaaggaatt a" /listShort="yqhY, S918, nusB, folD, S917, xseA, xseB, ispA" /listLong="S916, dxs, yqxC, S915, ahrC, recN" /label="promotor_-35" CDS complement(2397316..2397795) /gene="accB" /locus_tag="BSU_24350" /old_locus_tag="BSU24350" /EC_number="6.4.1.2" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:7592499, 12682299, 14594796, 15518551" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7592499, 12682299, 14594796, 15518551; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="acetyl-CoA carboxylase subunit (biotin carboxyl carrier subunit)" /protein_id="NP_390315.1" /db_xref="EnsemblGenomes-Gn:BSU24350" /db_xref="EnsemblGenomes-Tr:CAB14366" /db_xref="GOA:P49786" /db_xref="InterPro:IPR000089" /db_xref="InterPro:IPR001249" /db_xref="InterPro:IPR001882" /db_xref="InterPro:IPR011053" /db_xref="SubtiList:BG11383" /db_xref="UniProtKB/Swiss-Prot:P49786" /translation="MLNIKEIHELIKAIDESTIDEFVYENEGVSLKLKKHEAGTVQVM QQAPAAPVQAQAPQAVQPQAQQAAAPAQEAPKQDENLHKITSPMVGTFYASSSPEAGP YVTAGSKVNENTVVCIVEAMKLFNEIEAEVKGEIVEVLVENGQLVEYGQPLFLVKAE* " gene complement(2397316..2397795) /gene="accB" /locus_tag="BSU_24350" /old_locus_tag="BSU24350" promotor_-10 complement(2397854..2397873) /Source="Nicolas_upshift_promotors" /id="U1898" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.727272727272727" /psig=1 /xcortree=2334 /SigmaFactorBS="caagcgggctttttgcgttgctgtcatattaGAGTTGAAttc aaaagtccgcTCCTGTAAGATGAACATAGTatgtacttttagtagtaacctataaaaa a" /listShort="accB, accC, yqhY, S918, nusB, folD, S917, xseA, xseB, ispA, S916, dxs, yqxC, S915, ahrC, recN" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2397865) /Source="Nicolas_upshifts" /id="U1898" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.727272727272727" /psig=1 /xcortree=2334 /SigmaFactorBS="caagcgggctttttgcgttgctgtcatattaGAGTTGAAttc aaaagtccgcTCCTGTAAGATGAACATAGTatgtacttttagtagtaacctataaaaa a" /listShort="accB, accC, yqhY, S918, nusB, folD, S917, xseA, xseB, ispA, S916, dxs, yqxC, S915, ahrC, recN" /GFF_Attribute="listLong" promotor_-35 complement(2397887..2397894) /Source="Nicolas_upshift_promotors" /id="U1898" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.727272727272727" /psig=1 /xcortree=2334 /SigmaFactorBS="caagcgggctttttgcgttgctgtcatattaGAGTTGAAttc aaaagtccgcTCCTGTAAGATGAACATAGTatgtacttttagtagtaacctataaaaa a" /listShort="accB, accC, yqhY, S918, nusB, folD, S917, xseA, xseB, ispA, S916, dxs, yqxC, S915, ahrC, recN" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2397951..2398607) /gene="spoIIIAH" /locus_tag="BSU_24360" /old_locus_tag="BSU24360" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:15028710, 15752199, 16959571, 1766372" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15028710, 15752199, 16959571, 1766372; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="stage III sporulation ratchet engulfment protein" /protein_id="NP_390316.2" /db_xref="EnsemblGenomes-Gn:BSU24360" /db_xref="EnsemblGenomes-Tr:CAB14367" /db_xref="GOA:P49785" /db_xref="InterPro:IPR024232" /db_xref="PDB:3TUF" /db_xref="PDB:3UZ0" /db_xref="SubtiList:BG11415" /db_xref="UniProtKB/Swiss-Prot:P49785" /translation="MLKKQTVWLLTMLSLVVVLSVYYIMSPESKNAVQMQSEKSASDS GEVATEKAPAKQDTKEKSGTETEKGKEDGTKGTKDSSADKETSAEASEKGTVVTETAD DDLFTTYRLDLEDARSKEREELNAIVSSDDATAKEKSEAYDKMTALSEVEGTEKQLET LIKTQGYEDALVNAEGDKINITVKSDKHSKSKATAIIDLVAKEIKTMKDVAVTFEPSK *" gene complement(2397951..2398607) /gene="spoIIIAH" /locus_tag="BSU_24360" /old_locus_tag="BSU24360" downshifts complement(2397958) /Source="Nicolas_upshifts" /id="D1270" /incds=0 /nref=26 /ntot=57 /MaxReadThrough="0.0903599999999987" /MaxDrop="6.40434" /score="21.0450747" /energy="-13" /TU="NA" /idTUdmin="U1899" /TUdmin="-18" /isTUend="TRUE" CDS complement(2398608..2399297) /gene="spoIIIAG" /locus_tag="BSU_24370" /old_locus_tag="BSU24370" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:1766372, 15028710, 28784753" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1766372, 15028710, 28784753; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="stage III sporulation engulfment assembly protein" /protein_id="NP_390317.2" /db_xref="EnsemblGenomes-Gn:BSU24370" /db_xref="EnsemblGenomes-Tr:CAB14368" /db_xref="GOA:P49784" /db_xref="InterPro:IPR014195" /db_xref="SubtiList:BG11414" /db_xref="UniProtKB/Swiss-Prot:P49784" /translation="MNKNGLWNVLKKQFLPGQTKDGEKPKLTKYHYFLFVFVLGVSFM LVSQLFSSPEKTENAKTITAVSSQHSADSKEKTAEVFKASKSDKPKDSIDDYEKEYEN QLKEILETIIGVDDVSVVVNVDATSLKVYEKNKSNKNTTTEETDKEGGKRSVTDQSSE EEIVMIKNGDKETPVVVQTKKPDIRGVLVVAQGVDNVQIKQTIIEAVTRVLDVPSHRV AVAPKKIKEDS*" gene complement(2398608..2399297) /gene="spoIIIAG" /locus_tag="BSU_24370" /old_locus_tag="BSU24370" CDS complement(2399290..2399910) /gene="spoIIIAF" /locus_tag="BSU_24380" /old_locus_tag="BSU24380" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:1766372, 15028710, 17693505, 28784753" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1766372, 15028710, 17693505, 28784753; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="stage III sporulation protein (feeding tube apparatus)" /protein_id="NP_390318.1" /db_xref="EnsemblGenomes-Gn:BSU24380" /db_xref="EnsemblGenomes-Tr:CAB14369" /db_xref="GOA:P49783" /db_xref="InterPro:IPR014245" /db_xref="SubtiList:BG11413" /db_xref="UniProtKB/Swiss-Prot:P49783" /translation="MSFLTEWLTTIVLFILFAIVIDMLLPSSSMQKYAKMVVSLLLIV VMLTPIFKLFKTDPEVIFEYLTKNGQSESADIKNQINSKKIEIQASQRAYILEEMAVQ LKKKAEERFSHDEYKVGRIKLTAGEKVDSEEDIKTISVYMAPSSEKTVQTVAPVHIDT DHAYVTKEAAEQKEAKQIQTQLADIWEIGSEKITVHMEGGESVGNE*" gene complement(2399290..2399910) /gene="spoIIIAF" /locus_tag="BSU_24380" /old_locus_tag="BSU24380" promotor_-10 complement(2399616..2399634) /Source="Nicolas_upshift_promotors" /id="U1899" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=981 /SigmaFactorBS="tctgccgacataaaaaatcaaatcaattcaaaaaaaataGAA ATAcaagcttcccagcgcGCATATATTCTAGAAGAAAtggctgtccaactaaaaaaga a" /listShort="spoIIIAG, spoIIIAH" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2399634) /Source="Nicolas_upshifts" /id="U1899" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=981 /SigmaFactorBS="tctgccgacataaaaaatcaaatcaattcaaaaaaaataGAA ATAcaagcttcccagcgcGCATATATTCTAGAAGAAAtggctgtccaactaaaaaaga a" /listShort="spoIIIAG, spoIIIAH" /GFF_Attribute="listLong" promotor_-35 complement(2399650..2399655) /Source="Nicolas_upshift_promotors" /id="U1899" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=981 /SigmaFactorBS="tctgccgacataaaaaatcaaatcaattcaaaaaaaataGAA ATAcaagcttcccagcgcGCATATATTCTAGAAGAAAtggctgtccaactaaaaaaga a" /listShort="spoIIIAG, spoIIIAH" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2399924..2401123) /gene="spoIIIAE" /locus_tag="BSU_24390" /old_locus_tag="BSU24390" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:1766372, 15028710, 15849754, 16850406, 28784753" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1766372, 15028710, 15849754, 16850406, 28784753; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="stage III sporulation protein (feeding tube apparatus)" /protein_id="NP_390319.2" /db_xref="EnsemblGenomes-Gn:BSU24390" /db_xref="EnsemblGenomes-Tr:CAB14370" /db_xref="GOA:P49782" /db_xref="InterPro:IPR014194" /db_xref="SubtiList:BG11412" /db_xref="UniProtKB/Swiss-Prot:P49782" /translation="MKRFQWVLLLAVLIIAGRAEIVQAAGNAEQTEDHAETAEQLAER TAASLETDKIGEFWNDIMTEYGGLLPESQKGSLMEFINGDKSFSPQEWLKALFSYLFH EVLANGKLLGTLILLTIFCVILQLLQNAFQQSTVSKVAYSIVYMVLIILALNSFHVAI NYATEAIQTMTSFILALIPLLLALLASSGGAVSAAFFHPVILFLMNTSGLLIQNIVMP LIFLSAILSIVSTMTEQYKVTQLANLLRNIAIGALAVFLTIFLGVISVQGASAAVTDG ITLRTAKFITGNFIPVLGRMFTDATDTVISASLLLKNTVGILGVAILICIAAFPAIKV LSLAFIYKLAAAILQPLGGGPVITCLDVISKSVIYIFAALAIVSLMFFLSLTVIITAG NLTMMMK*" gene complement(2399924..2401123) /gene="spoIIIAE" /locus_tag="BSU_24390" /old_locus_tag="BSU24390" CDS complement(2401142..2401543) /gene="spoIIIAD" /locus_tag="BSU_24400" /old_locus_tag="BSU24400" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:1766372, 15028710, 15849754, 16850406, 28784753" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1766372, 15028710, 15849754, 16850406, 28784753; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="stage III sporulation protein (feeding tube apparatus)" /protein_id="NP_390320.1" /db_xref="EnsemblGenomes-Gn:BSU24400" /db_xref="EnsemblGenomes-Tr:CAB14371" /db_xref="GOA:P49781" /db_xref="InterPro:IPR014211" /db_xref="InterPro:IPR025664" /db_xref="SubtiList:BG11411" /db_xref="UniProtKB/Swiss-Prot:P49781" /translation="MQIDIVQIVGLGLIATFLSLIVKEQKPTFAFLIVVFAGCAIFLY LVDQIYDIIRMIEKIAINANVNMVYVETILKIIGIAYIAEFGAQLTKDAGQGAIASKI ELAGKILILVMAVPILTVIIETILGLIPSMS*" gene complement(2401142..2401543) /gene="spoIIIAD" /locus_tag="BSU_24400" /old_locus_tag="BSU24400" CDS complement(2401550..2401756) /gene="spoIIIAC" /locus_tag="BSU_24410" /old_locus_tag="BSU24410" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:1766372, 15028710, 17693505, 28784753" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1766372, 15028710, 17693505, 28784753; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="stage III sporulation protein (feeding tube apparatus)" /protein_id="NP_390321.1" /db_xref="EnsemblGenomes-Gn:BSU24410" /db_xref="EnsemblGenomes-Tr:CAB14372" /db_xref="GOA:P49780" /db_xref="InterPro:IPR009570" /db_xref="InterPro:IPR025664" /db_xref="SubtiList:BG11410" /db_xref="UniProtKB/Swiss-Prot:P49780" /translation="MGVDVNVIFQIAGVGIVVAFLHTILDQMGKKEYAQWVTLLGFIY ILFMVATIVDDLFKKIKAVFLFQG*" gene complement(2401550..2401756) /gene="spoIIIAC" /locus_tag="BSU_24410" /old_locus_tag="BSU24410" CDS complement(2401779..2402294) /gene="spoIIIAB" /locus_tag="BSU_24420" /old_locus_tag="BSU24420" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:1766372, 15028710, 17693505, 28784753" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1766372, 15028710, 17693505, 28784753; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="stage III sporulation protein (feeding tube apparatus)" /protein_id="NP_390322.1" /db_xref="EnsemblGenomes-Gn:BSU24420" /db_xref="EnsemblGenomes-Tr:CAB14373" /db_xref="GOA:Q01368" /db_xref="InterPro:IPR014198" /db_xref="SubtiList:BG10541" /db_xref="UniProtKB/Swiss-Prot:Q01368" /translation="MLKLLGAVFIVVATTWTGFEMAKIYTERPRQIRQLRAALQSLEA EIMYGHTPLHTASQQIAKQLAQPVSTLFSAFSDQLDKGSDSAKTAWEQSLKKVWDTLS LKKSEYEVLKQFGETLGIHDRISQQKHIKLALTHLEASEADAEQAQAKNEKMIKSLGF LAGLLLILLLM*" gene complement(2401779..2402294) /gene="spoIIIAB" /locus_tag="BSU_24420" /old_locus_tag="BSU24420" CDS complement(2402288..2403211) /gene="spoIIIAA" /locus_tag="BSU_24430" /old_locus_tag="BSU24430" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:1766372, 15028710, 17693505, 28784753" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1766372, 15028710, 17693505, 28784753; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="ATP-binding stage III sporulation protein" /protein_id="NP_390323.1" /db_xref="EnsemblGenomes-Gn:BSU24430" /db_xref="EnsemblGenomes-Tr:CAB14374" /db_xref="GOA:Q01367" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR014217" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG10540" /db_xref="UniProtKB/Swiss-Prot:Q01367" /translation="MNEIAEVLPESMKNALSEIPEQQWLEIEEVRIRINRPVELIRRG QPVYLSYAGTAEDAHLILSRLSNYSMYTLEEELKKGYVTIRGGHRVGLAGRVITENGG VKGLRDIASFNIRIARQKLGIAEPLLPYLYQNSWLNTLIIGPPQTGKTTLLRDLARLS STGKKNMLPVKTGIVDERSEIAGCLRGIPQHQFGQRIDVLDACPKAEGLMMMIRSMSP EVMIVDEIGRMEDTDALLEALHAGVSVIVSAHGWSISDLMKRPSLKRLWEERAFDRYL ELSRAKGPGTVSQIYDKDGNVLSRTTGVKTC*" gene complement(2402288..2403211) /gene="spoIIIAA" /locus_tag="BSU_24430" /old_locus_tag="BSU24430" S_feature complement(2403212..2403286) /Source="Nicolas_S_feature" /locus_tag="new_2537614_2537688_c" /HighExp="S3, LoTm, S4, T5.0H, M9-stat, S5, BT, S7, S6, T4.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigEF" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S919" CDS complement(2403287..2403568) /gene="yqhV" /locus_tag="BSU_24440" /old_locus_tag="BSU24440" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_390324.1" /db_xref="EnsemblGenomes-Gn:BSU24440" /db_xref="EnsemblGenomes-Tr:CAB14375" /db_xref="GOA:P49779" /db_xref="InterPro:IPR020390" /db_xref="SubtiList:BG11459" /db_xref="UniProtKB/Swiss-Prot:P49779" /translation="MKFLLGNINSTVLTMAGLRVLSSMIELTAAIVMLVTNDVRKAVV VNSILAIVGPLIFIITMTVGIYQIAGQLSYAKLILIFTGVVLILAGVHK*" gene complement(2403287..2403568) /gene="yqhV" /locus_tag="BSU_24440" /old_locus_tag="BSU24440" promotor_-10 complement(2403588..2403606) /Source="Nicolas_upshift_promotors" /id="U1900" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=992 /SigmaFactorBS="ttttgtgcccaaaaacagaatctttcttttatacgaaaatga caAGACTActtcagcaagctagaGCATATCATATAAAAAAATgggaggttgggagagt g" /listShort="yqhV, S919, spoIIIAA, spoIIIAB, spoIIIAC, spoIIIAD, spoIIIAE, spoIIIAF" /listLong="spoIIIAG, spoIIIAH" /label="promotor_-10" upshifts complement(2403611) /Source="Nicolas_upshifts" /id="U1900" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=992 /SigmaFactorBS="ttttgtgcccaaaaacagaatctttcttttatacgaaaatga caAGACTActtcagcaagctagaGCATATCATATAAAAAAATgggaggttgggagagt g" /listShort="yqhV, S919, spoIIIAA, spoIIIAB, spoIIIAC, spoIIIAD, spoIIIAE, spoIIIAF" /listLong="spoIIIAG, spoIIIAH" promotor_-35 complement(2403622..2403627) /Source="Nicolas_upshift_promotors" /id="U1900" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=992 /SigmaFactorBS="ttttgtgcccaaaaacagaatctttcttttatacgaaaatga caAGACTActtcagcaagctagaGCATATCATATAAAAAAATgggaggttgggagagt g" /listShort="yqhV, S919, spoIIIAA, spoIIIAB, spoIIIAC, spoIIIAD, spoIIIAE, spoIIIAF" /listLong="spoIIIAG, spoIIIAH" /label="promotor_-35" CDS complement(2403713..2404270) /gene="efp" /locus_tag="BSU_24450" /old_locus_tag="BSU24450" /function="16.6: Maintain" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:1956781, 14586115, 15066026, 15210970, 16014871, 27002156, 28787546" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1956781, 14586115, 15066026, 15210970, 16014871, 27002156, 28787546; Product type f: factor" /codon_start=1 /transl_table=11 /product="elongation factor P" /protein_id="NP_390325.2" /db_xref="EnsemblGenomes-Gn:BSU24450" /db_xref="EnsemblGenomes-Tr:CAB14376" /db_xref="GOA:P49778" /db_xref="InterPro:IPR001059" /db_xref="InterPro:IPR008991" /db_xref="InterPro:IPR011768" /db_xref="InterPro:IPR012340" /db_xref="InterPro:IPR013185" /db_xref="InterPro:IPR013852" /db_xref="InterPro:IPR014722" /db_xref="InterPro:IPR015365" /db_xref="InterPro:IPR020599" /db_xref="SubtiList:BG11460" /db_xref="UniProtKB/Swiss-Prot:P49778" /translation="MISVNDFRTGLTIEVDGGIWRVVDFQHVKPGKGAAFVRSKLRNL RTGAIQEKTFRAGEKVAKAQIETKTMQYLYANGDQHVFMDTSSYEQLELSATQIEEEL KYLLENMSVHIMMYQDETLGIELPNTVELKVVETEPGIKGDTASGGTKPAKTETGLVV NVPFFVNEGDTLVVNTSDGSYVSRA*" gene complement(2403713..2404270) /gene="efp" /locus_tag="BSU_24450" /old_locus_tag="BSU24450" downshifts complement(2403725) /Source="Nicolas_upshifts" /id="D1271" /incds=0 /nref=256 /ntot=266 /MaxReadThrough="0.83852" /MaxDrop="7.73118" /score="27.4193827" /energy="-13.5" /TU="NA" /idTUdmin="U1901" /TUdmin=0 /isTUend="TRUE" CDS complement(2404295..2405356) /gene="papA" /locus_tag="BSU_24460" /old_locus_tag="BSU24460" /EC_number="3.4.-.-" /function="16.6: Maintain" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:23144141, 26735940, 27002156" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 23144141, 26735940, 27002156; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="aminopeptidase (Met-Xaa and Xaa-Pro, Xaa-Pro-Xaa)" /protein_id="NP_390326.1" /db_xref="EnsemblGenomes-Gn:BSU24460" /db_xref="EnsemblGenomes-Tr:CAB14377" /db_xref="GOA:P54518" /db_xref="InterPro:IPR000587" /db_xref="InterPro:IPR000994" /db_xref="InterPro:IPR001131" /db_xref="InterPro:IPR001714" /db_xref="InterPro:IPR029149" /db_xref="InterPro:IPR036005" /db_xref="SubtiList:BG11708" /db_xref="UniProtKB/Swiss-Prot:P54518" /translation="MKLEKLRNLFGQLGIDGMLITSNTNVRYMTGFTGSAGLAVISGD KAAFITDFRYTEQAKVQVKGFEIIEHGGSLIQTTADTVESFGIKRLGFEQNSMTYGTY ASYSAVISDAELVPVAESVEKLRLIKSSEEIKILEEAAKIADDAFRHILTFMKPGISE IAVANELEFYMRSQGADSSSFDMIVASGLRSSLPHGVASDKLIESGDLVTLDFGAYYK GYCSDITRTVAVGQPSDQLKEIYQVVFDAQALGVAHIKPGMTGKEADALTRDHIAAKG YGDYFGHSTGHGLGMEVHESPGLSVRSSAILEPGMVVTVEPGIYIPETGGVRIEDDIV ITENGNRTITHSPKELIIL*" gene complement(2404295..2405356) /gene="papA" /locus_tag="BSU_24460" /old_locus_tag="BSU24460" CDS complement(2405353..2405799) /gene="yqhS" /locus_tag="BSU_24470" /old_locus_tag="BSU24470" /EC_number="4.2.1.10" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 10870960, 19099550; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="3-dehydroquinate dehydratase, type II" /protein_id="NP_390327.1" /db_xref="EnsemblGenomes-Gn:BSU24470" /db_xref="EnsemblGenomes-Tr:CAB14378" /db_xref="GOA:P54517" /db_xref="InterPro:IPR001874" /db_xref="InterPro:IPR018509" /db_xref="InterPro:IPR036441" /db_xref="PDB:1GQO" /db_xref="SubtiList:BG11707" /db_xref="UniProtKB/Swiss-Prot:P54517" /translation="MPHFLILNGPNVNRLGSREPEVFGRQTLTDIETDLFQFAEALHI QLTFFQSNHEGDLIDAIHEAEEQYSGIVLNPGALSHYSYAIRDAVSSISLPVVEVHLS NLYAREEFRHQSVIAPVAKGQIVGLGAEGYKLAVRYLLSQQGGESR*" gene complement(2405353..2405799) /gene="yqhS" /locus_tag="BSU_24470" /old_locus_tag="BSU24470" promotor_-10 complement(2405848..2405867) /Source="Nicolas_upshift_promotors" /id="U1901" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.485514485514486" /psig="0.999000999001" /xcortree=2230 /SigmaFactorBS="gaaaagcttgcacgtgcgctgggaatgcatagagaatAGTGT ATAatccttttccagTATGATAAAATGTTCACGAGaagtgaacattttttacatgaga a" /listShort="yqhS, yqhT, efp" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2405864) /Source="Nicolas_upshifts" /id="U1901" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.485514485514486" /psig="0.999000999001" /xcortree=2230 /SigmaFactorBS="gaaaagcttgcacgtgcgctgggaatgcatagagaatAGTGT ATAatccttttccagTATGATAAAATGTTCACGAGaagtgaacattttttacatgaga a" /listShort="yqhS, yqhT, efp" /GFF_Attribute="listLong" promotor_-35 complement(2405880..2405887) /Source="Nicolas_upshift_promotors" /id="U1901" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.485514485514486" /psig="0.999000999001" /xcortree=2230 /SigmaFactorBS="gaaaagcttgcacgtgcgctgggaatgcatagagaatAGTGT ATAatccttttccagTATGATAAAATGTTCACGAGaagtgaacattttttacatgaga a" /listShort="yqhS, yqhT, efp" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2405886..2406422) /gene="yqhR" /locus_tag="BSU_24480" /old_locus_tag="BSU24480" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative integral inner membrane protein" /protein_id="NP_390328.1" /db_xref="EnsemblGenomes-Gn:BSU24480" /db_xref="EnsemblGenomes-Tr:CAB14379" /db_xref="GOA:P54516" /db_xref="InterPro:IPR024563" /db_xref="SubtiList:BG11706" /db_xref="UniProtKB/Swiss-Prot:P54516" /translation="MMTSEKDTEQNEELNEKQKPPVSMAGRVAATGFCGGVLWSFVAY IAYLFHFSEISPNMILQPFVLGEWKKHGLGTVISIILIGVISIGAAFLYFLLLKRLKT MWPGILYGLVLWLLVFFVFNPIFPDVRTVTELTSDTIITTICIYLLYGLFVGYSISFE YNELNSEKLARALGMHRE*" gene complement(2405886..2406422) /gene="yqhR" /locus_tag="BSU_24480" /old_locus_tag="BSU24480" promotor_-10 complement(2406435..2406446) /Source="Nicolas_upshift_promotors" /id="U1902" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.976023976023976" /psig="0.976023976023976" /xcortree=905 /SigmaFactorBS="caaattttactcgcagctgccaaaaagtgtgagcttttTTAT TGAcatttcattttttGGGCACACTTTAactggaggtgccatgatgacaagcgaaaaa g" /listShort="yqhR" /listLong="yqhS, yqhT, efp" /label="promotor_-10" upshifts complement(2406444) /Source="Nicolas_upshifts" /id="U1902" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.976023976023976" /psig="0.976023976023976" /xcortree=905 /SigmaFactorBS="caaattttactcgcagctgccaaaaagtgtgagcttttTTAT TGAcatttcattttttGGGCACACTTTAactggaggtgccatgatgacaagcgaaaaa g" /listShort="yqhR" /listLong="yqhS, yqhT, efp" promotor_-35 complement(2406460..2406466) /Source="Nicolas_upshift_promotors" /id="U1902" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.976023976023976" /psig="0.976023976023976" /xcortree=905 /SigmaFactorBS="caaattttactcgcagctgccaaaaagtgtgagcttttTTAT TGAcatttcattttttGGGCACACTTTAactggaggtgccatgatgacaagcgaaaaa g" /listShort="yqhR" /listLong="yqhS, yqhT, efp" /label="promotor_-35" promotor_-35 2406492..2406498 /Source="Nicolas_upshift_promotors" /id="U1903" /multdbtbs="SigB,SigF" /comp="M11" /sig="SigB" /pcomp="0.995004995004995" /psig="0.995004995004995" /xcortree=746 /SigmaFactorBS="aatgaaatgtcaataaaaaagctcacactttttggcagctgC GAGTAAaatttgaaaataacGGGTATAATGCATGTAGAAaaagcaaggctatggcaat t" /listShort="yqhQ, yqhP" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 2406511 /Source="Nicolas_upshifts" /id="U1903" /multdbtbs="SigB,SigF" /comp="M11" /sig="SigB" /pcomp="0.995004995004995" /psig="0.995004995004995" /xcortree=746 /SigmaFactorBS="aatgaaatgtcaataaaaaagctcacactttttggcagctgC GAGTAAaatttgaaaataacGGGTATAATGCATGTAGAAaaagcaaggctatggcaat t" /listShort="yqhQ, yqhP" /GFF_Attribute="listLong" promotor_-10 2406513..2406531 /Source="Nicolas_upshift_promotors" /id="U1903" /multdbtbs="SigB,SigF" /comp="M11" /sig="SigB" /pcomp="0.995004995004995" /psig="0.995004995004995" /xcortree=746 /SigmaFactorBS="aatgaaatgtcaataaaaaagctcacactttttggcagctgC GAGTAAaatttgaaaataacGGGTATAATGCATGTAGAAaaagcaaggctatggcaat t" /listShort="yqhQ, yqhP" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 2406568..2406571 /Source="Nicolas_upshift_promotors" /id="U1904" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.963036963036963" /psig=1 /xcortree=3141 /SigmaFactorBS="aaggctatggcaattttttcagcctgtcaatCTAGaggttta gcgctgtTTCCTGTACAATAGAGTGAAaggaaatggttagcaatcctaaagaaatagg c" /listShort="yqhQ, yqhP" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2406586..2406605 /Source="Nicolas_upshift_promotors" /id="U1904" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.963036963036963" /psig=1 /xcortree=3141 /SigmaFactorBS="aaggctatggcaattttttcagcctgtcaatCTAGaggttta gcgctgtTTCCTGTACAATAGAGTGAAaggaaatggttagcaatcctaaagaaatagg c" /listShort="yqhQ, yqhP" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2406597 /Source="Nicolas_upshifts" /id="U1904" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.963036963036963" /psig=1 /xcortree=3141 /SigmaFactorBS="aaggctatggcaattttttcagcctgtcaatCTAGaggttta gcgctgtTTCCTGTACAATAGAGTGAAaggaaatggttagcaatcctaaagaaatagg c" /listShort="yqhQ, yqhP" /GFF_Attribute="listLong" CDS 2406649..2407605 /gene="yqhQ" /locus_tag="BSU_24490" /old_locus_tag="BSU24490" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_390329.2" /db_xref="EnsemblGenomes-Gn:BSU24490" /db_xref="EnsemblGenomes-Tr:CAB14380" /db_xref="GOA:P54515" /db_xref="InterPro:IPR010787" /db_xref="SubtiList:BG11705" /db_xref="UniProtKB/Swiss-Prot:P54515" /translation="MSKHKVPPAYGGQAVVEGVMFGGKHHYVTAIRRTDGSIDFFKLP RKHNPKLNIVKKIPFLRGIAAIIEASANGTKHLNFSSERYGLDPSEDETLEQEEKKSS GLSMYLSLAVIGVLSFLFSKFVFTLVPVFLAELTRPIFSLNTAQIAIESLFKLILLLG YIYFLSMTPLIKRVFQYHGAEHKVINCYEQNLPITVENVQNQSRLHYRCGSSFILFTI IVGMFVYLLVPTDPLWLRVIDRVALIPVVLGISFEVLQLTNKVRDIPGLKLLGYPGLW LQLLTTKEPKDEQVEVAIESFNELLRLEALSEQNQKPSHNVI*" gene 2406649..2407605 /gene="yqhQ" /locus_tag="BSU_24490" /old_locus_tag="BSU24490" CDS 2407645..2408040 /gene="yqhP" /locus_tag="BSU_24500" /old_locus_tag="BSU24500" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_390330.1" /db_xref="EnsemblGenomes-Gn:BSU24500" /db_xref="EnsemblGenomes-Tr:CAB14381" /db_xref="GOA:P54514" /db_xref="SubtiList:BG11704" /db_xref="UniProtKB/Swiss-Prot:P54514" /translation="MNHRVQPIIAVLIALGAFGFLYVLVTNPGEMAKMAVTVIVAGII IYFIVKYVMNRNAGSEGAAFKKAAKQSRRRMKEQKAKHRAGHKGRVSHLRSVPSASKP KPMILKKKSQTQLTVIEGKKNKKKNRALF*" gene 2407645..2408040 /gene="yqhP" /locus_tag="BSU_24500" /old_locus_tag="BSU24500" promotor_no_box 2407923..2408023 /Source="Nicolas_upshift_promotors" /id="U1905" /multdbtbs="-" /comp="M21" /sig="Sig-" /pcomp="0.578421578421578" /psig="0.007992007992008" /xcortree=275 /SigmaFactorBS="gcgaagcgttccgagcgccagcaagcctaagccgatgattct caagaaaaaaagccagactcagctgactgttatagaagggaaaaaaaataaaaagaaa a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_no_box" upshifts 2407983 /Source="Nicolas_upshifts" /id="U1905" /multdbtbs="-" /comp="M21" /sig="Sig-" /pcomp="0.578421578421578" /psig="0.007992007992008" /xcortree=275 /SigmaFactorBS="gcgaagcgttccgagcgccagcaagcctaagccgatgattct caagaaaaaaagccagactcagctgactgttatagaagggaaaaaaaataaaaagaaa a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" downshifts 2408026 /Source="Nicolas_upshifts" /id="D1272" /incds=0 /nref=116 /ntot=283 /MaxReadThrough="2.23161" /MaxDrop="5.94415" /score="29.0609078" /energy="-8" /TU="NA" /idTUdmin="U1903" /TUdmin="-1" /isTUend="TRUE" CDS complement(2408037..2408912) /gene="yqhO" /locus_tag="BSU_24510" /old_locus_tag="BSU24510" /EC_number="3.1.1.-" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative lipase / acyl esterase" /protein_id="NP_390331.1" /db_xref="EnsemblGenomes-Gn:BSU24510" /db_xref="EnsemblGenomes-Tr:CAB14382" /db_xref="GOA:P54513" /db_xref="InterPro:IPR002641" /db_xref="InterPro:IPR016035" /db_xref="SubtiList:BG11703" /db_xref="UniProtKB/Swiss-Prot:P54513" /translation="MYIDGVFSGGGVKGIALAGAYEVLEEKGFRFKRVAGTSAGAIIA AFIASGYTSKEIHALIEEVDGEKLLDQRYSFLPLKMLQWVSIYWRLGLYKGDTIEKWI ADLLRAKGIRVFGDLQKGSLRLIASDLTNGTMIVLPDDLARYGLNPDMFPVARAVRMS CSIPYFFEPIKLKTDTGTATVVDGGVLSNFPIWLFSKERKRPVIGVTLAPRERERPKK NIRNAFELFGALFETMKDAHDARHIASRYEQNIIFLPVDDVMATDFHLTQQKKLALIE LGKRRTELFLKQWTY*" gene complement(2408037..2408912) /gene="yqhO" /locus_tag="BSU_24510" /old_locus_tag="BSU24510" promotor_-10 complement(2408939..2408957) /Source="Nicolas_upshift_promotors" /id="U1906" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.986013986013986" /psig="0.986013986013986" /xcortree=1086 /SigmaFactorBS="cgtcttttttgatacgctgacgccacccgtcattcgttGGTC TAtttcttcgcgtgtttTCTTAAAATGGTAATAAACgatcggatggagggggagggaa t" /listShort="yqhO" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2408956) /Source="Nicolas_upshifts" /id="U1906" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.986013986013986" /psig="0.986013986013986" /xcortree=1086 /SigmaFactorBS="cgtcttttttgatacgctgacgccacccgtcattcgttGGTC TAtttcttcgcgtgtttTCTTAAAATGGTAATAAACgatcggatggagggggagggaa t" /listShort="yqhO" /GFF_Attribute="listLong" promotor_-35 complement(2408973..2408978) /Source="Nicolas_upshift_promotors" /id="U1906" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.986013986013986" /psig="0.986013986013986" /xcortree=1086 /SigmaFactorBS="cgtcttttttgatacgctgacgccacccgtcattcgttGGTC TAtttcttcgcgtgtttTCTTAAAATGGTAATAAACgatcggatggagggggagggaa t" /listShort="yqhO" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2409038..2409466) /gene="mntR" /locus_tag="BSU_24520" /old_locus_tag="BSU24520" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:12950915, 15948947, 16533030, 17118401, 17176058, 17342524, 27748968, 28223356" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12950915, 15948947, 16533030, 17118401, 17176058, 17342524, 27748968, 28223356; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator (hydrogen peroxide sensing, allosterically regulated by Mn2+)" /protein_id="NP_390332.2" /db_xref="EnsemblGenomes-Gn:BSU24520" /db_xref="EnsemblGenomes-Tr:CAB14383" /db_xref="GOA:P54512" /db_xref="InterPro:IPR001367" /db_xref="InterPro:IPR022687" /db_xref="InterPro:IPR022689" /db_xref="InterPro:IPR022897" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="InterPro:IPR036421" /db_xref="PDB:1ON1" /db_xref="PDB:1ON2" /db_xref="PDB:2EV0" /db_xref="PDB:2EV5" /db_xref="PDB:2EV6" /db_xref="PDB:2F5C" /db_xref="PDB:2F5D" /db_xref="PDB:2F5E" /db_xref="PDB:2F5F" /db_xref="PDB:2HYF" /db_xref="PDB:2HYG" /db_xref="PDB:3R60" /db_xref="PDB:3R61" /db_xref="PDB:4HV5" /db_xref="PDB:4HV6" /db_xref="PDB:4HX4" /db_xref="PDB:4HX7" /db_xref="PDB:4HX8" /db_xref="SubtiList:BG11702" /db_xref="UniProtKB/Swiss-Prot:P54512" /translation="MTTPSMEDYIEQIYMLIEEKGYARVSDIAEALAVHPSSVTKMVQ KLDKDEYLIYEKYRGLVLTSKGKKIGKRLVYRHELLEQFLRIIGVDEEKIYNDVEGIE HHLSWNSIDRIGDLVQYFEEDDARKKDLKSIQKKTEHHNQ*" gene complement(2409038..2409466) /gene="mntR" /locus_tag="BSU_24520" /old_locus_tag="BSU24520" downshifts complement(2409065) /Source="Nicolas_upshifts" /id="D1273" /incds=0 /nref=322 /ntot=333 /MaxReadThrough="2.568" /MaxDrop="7.28707" /score="15.888362" /energy="-12" /TU="NA" /idTUdmin="U1908" /TUdmin=6 /isTUend="TRUE" promotor_-10 complement(2409501..2409520) /Source="Nicolas_upshift_promotors" /id="U1907" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.97902097902098" /psig=1 /xcortree=2459 /SigmaFactorBS="gtaaacagggcttttgacccgcggagcatCCTTGttttttca agttcatTAGTGTAAACTTGTAATGGTttataaagttaaggtgctttttgggagggtt t" /listShort="mntR" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2409509) /Source="Nicolas_upshifts" /id="U1907" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.97902097902098" /psig=1 /xcortree=2459 /SigmaFactorBS="gtaaacagggcttttgacccgcggagcatCCTTGttttttca agttcatTAGTGTAAACTTGTAATGGTttataaagttaaggtgctttttgggagggtt t" /listShort="mntR" /GFF_Attribute="listLong" promotor_-35 complement(2409536..2409540) /Source="Nicolas_upshift_promotors" /id="U1907" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.97902097902098" /psig=1 /xcortree=2459 /SigmaFactorBS="gtaaacagggcttttgacccgcggagcatCCTTGttttttca agttcatTAGTGTAAACTTGTAATGGTttataaagttaaggtgctttttgggagggtt t" /listShort="mntR" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2409566..2410402) /gene="lipM" /locus_tag="BSU_24530" /old_locus_tag="BSU24530" /EC_number="2.3.1.181" /function="3: Fatty acid and phospholipid metabolism" /experiment="publication(s) with functional evidences, PMID:20882995, 21338420, 21338421, 23960015" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 20882995, 21338420, 21338421, 23960015; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="protein octanoyltransferase" /protein_id="NP_390333.1" /db_xref="EnsemblGenomes-Gn:BSU24530" /db_xref="EnsemblGenomes-Tr:CAB14384" /db_xref="GOA:P54511" /db_xref="InterPro:IPR004143" /db_xref="InterPro:IPR024898" /db_xref="SubtiList:BG11701" /db_xref="UniProtKB/Swiss-Prot:P54511" /translation="MQKETWRFIDSGNASPAFNMALDEALLYWHSEKKIPPVIRFYGW NPATLSVGYFQNIKKEINFEAVHKYNLGFVRRPTGGRGVLHDQELTYSVIVSEEHPEM PATVTEAYRVISEGILQGFRNLGLDAYFAIPRTEKEKESLKNPRSSVCFDAPSWYELV VEGRKVAGSAQTRQKGVILQHGSILLDLDEDKLFDLFLYPSERVRERMQRNFKNKAVA INELIEKRVTMDEARKAFKEGFETGLNIHLEPYELSQEELDFVHHLAETKYASDEWNY KR*" gene complement(2409566..2410402) /gene="lipM" /locus_tag="BSU_24530" /old_locus_tag="BSU24530" promotor_-10 complement(2410426..2410445) /Source="Nicolas_upshift_promotors" /id="U1908" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.697302697302697" /psig="0.997002997002997" /xcortree=2353 /SigmaFactorBS="agcgtgattgtcatctataatggaactaaaaTATTTTTCatt ttcccgacagTTTGATAAACTGATTCTATTaaaacggtaaggaaggtcttaaaatgca a" /listShort="yqhM, mntR" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2410437) /Source="Nicolas_upshifts" /id="U1908" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.697302697302697" /psig="0.997002997002997" /xcortree=2353 /SigmaFactorBS="agcgtgattgtcatctataatggaactaaaaTATTTTTCatt ttcccgacagTTTGATAAACTGATTCTATTaaaacggtaaggaaggtcttaaaatgca a" /listShort="yqhM, mntR" /GFF_Attribute="listLong" S_feature complement(2410439..2410983) /Source="Nicolas_S_feature" /locus_tag="new_2544841_2545385_c" /HighExp="Lbstat, LPhT, HiOs, M0t90, S1, M40t90, Sw, S0, B36, BC" /AntisenseName="yqhL" /AntisenseCor="-0.136624541005539" /AntisenseRegPval="-1.6" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.995" /TUlongSig="NA" /TUlongPSig="NA" /label="S920" promotor_-35 complement(2410459..2410466) /Source="Nicolas_upshift_promotors" /id="U1908" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.697302697302697" /psig="0.997002997002997" /xcortree=2353 /SigmaFactorBS="agcgtgattgtcatctataatggaactaaaaTATTTTTCatt ttcccgacagTTTGATAAACTGATTCTATTaaaacggtaaggaaggtcttaaaatgca a" /listShort="yqhM, mntR" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 2410483..2410488 /Source="Nicolas_upshift_promotors" /id="U1909" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.458541458541459" /psig=1 /xcortree=2522 /SigmaFactorBS="caaactgtcgggaaaatgaaaaatattttagttccattataG ATGACaatcacgctgtgcTTTACTATAATAGTATTTGTcgaaaacggctctatgacct t" /listShort="S921, yqhL" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2410502..2410521 /Source="Nicolas_upshift_promotors" /id="U1909" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.458541458541459" /psig=1 /xcortree=2522 /SigmaFactorBS="caaactgtcgggaaaatgaaaaatattttagttccattataG ATGACaatcacgctgtgcTTTACTATAATAGTATTTGTcgaaaacggctctatgacct t" /listShort="S921, yqhL" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2410502 /Source="Nicolas_upshifts" /id="U1909" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.458541458541459" /psig=1 /xcortree=2522 /SigmaFactorBS="caaactgtcgggaaaatgaaaaatattttagttccattataG ATGACaatcacgctgtgcTTTACTATAATAGTATTTGTcgaaaacggctctatgacct t" /listShort="S921, yqhL" /GFF_Attribute="listLong" S_feature 2410513..2410592 /Source="Nicolas_S_feature" /locus_tag="new_2544915_2544994" /HighExp="dia15, H2O2, dia5, Diami, MG-0.2, G180, UNK1, LBGexp, Heat, MG 15" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S921" CDS 2410593..2410973 /gene="yqhL" /locus_tag="BSU_24540" /old_locus_tag="BSU24540" /function="5.5: Sulfur metabolism" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 11092948; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative sulfur transferase" /protein_id="NP_390334.2" /db_xref="EnsemblGenomes-Gn:BSU24540" /db_xref="EnsemblGenomes-Tr:CAB14385" /db_xref="GOA:P54510" /db_xref="InterPro:IPR001763" /db_xref="InterPro:IPR036873" /db_xref="SubtiList:BG11700" /db_xref="UniProtKB/Swiss-Prot:P54510" /translation="MSNMIVLIIFAAFIIYMIASYVYQQRIMKTLTEEEFRAGYRKAQ LIDVREPNEFEGGHILGARNIPLSQLKQRKNEIRTDKPVYLYCQNSVRSGRAAQTLRK NGCTEIYNLKGGFKKWGGKIKAKK*" gene 2410593..2410973 /gene="yqhL" /locus_tag="BSU_24540" /old_locus_tag="BSU24540" downshifts 2410909 /Source="Nicolas_upshifts" /id="D1274" /incds=1 /nref=1 /ntot=1 /MaxReadThrough="6.17088" /MaxDrop="3.92673" /score="27.1863605" /energy="-12" /TU="U1909" /idTUdmin="U1909" /TUdmin="-44" /isTUend="FALSE" downshifts 2410953 /Source="Nicolas_upshifts" /id="D1275" /incds=0 /nref=213 /ntot=249 /MaxReadThrough="2.26861" /MaxDrop="6.03848" /score="27.1863605" /energy="-12" /TU="NA" /idTUdmin="U1909" /TUdmin=0 /isTUend="TRUE" CDS complement(2411008..2412474) /gene="gcvPB" /locus_tag="BSU_24550" /old_locus_tag="BSU24550" /EC_number="1.4.4.2" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:8181752, 20011599, 22720735, 23721735, 29089431" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8181752, 20011599, 22720735, 23721735, 29089431; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="glycine decarboxylase (subunit 2) (glycine cleavage system protein P)" /protein_id="NP_390335.1" /db_xref="EnsemblGenomes-Gn:BSU24550" /db_xref="EnsemblGenomes-Tr:CAB14386" /db_xref="GOA:P54377" /db_xref="InterPro:IPR015421" /db_xref="InterPro:IPR015422" /db_xref="InterPro:IPR015424" /db_xref="InterPro:IPR020581" /db_xref="InterPro:IPR023012" /db_xref="SubtiList:BG11511" /db_xref="UniProtKB/Swiss-Prot:P54377" /translation="MSNQDQALIFELSREGRIGYSLPELDVPEIELGDLLSDTYIRDE DAALPEVSELDIMRHYTALSKRNHGVDSGFYPLGSCTMKYNPKINEKIARIPGFAAIH PLQDEDTVQGALELLYDLSKHLEEITGMDEVTLQPAAGAHGEWTGLMMIRAYHEARGD FKRTKVIVPDSAHGTNPASATVAGFETVTVKSNEKGLVDLEDLKRAVNEETAALMLTN PNTLGLFEEQITEMAEIVHQAGGKLYYDGANLNAVLSKARPGDMGFDVVHLNLHKTFT GPHGGGGPGSGPVGVKQDLIPYLPKPVLVKKEGRFTFDYDRPHAIGRVKPYYGNFGIN VRAYTYIRSMGPDGLKAVTENAVLNANYMMRKLAPYYDLPFDRHCKHEFVLSGKRQKK LGVRTLDIAKRLLDFGYHPPTIYFPLNVEECIMIEPTETESKETLDAFIDAMIQIAKE AEENPELVQEAPHTTIVKRMDETKAARHPVLRYEAEER*" gene complement(2411008..2412474) /gene="gcvPB" /locus_tag="BSU_24550" /old_locus_tag="BSU24550" downshifts complement(2411028) /Source="Nicolas_upshifts" /id="D1276" /incds=0 /nref=31 /ntot=215 /MaxReadThrough="3.45831" /MaxDrop="4.3142" /score="0.884126414" /energy="-12" /TU="U1911" /idTUdmin="U1911" /TUdmin="-1517" /isTUend="FALSE" CDS complement(2412467..2413813) /gene="gcvPA" /locus_tag="BSU_24560" /old_locus_tag="BSU24560" /EC_number="1.4.4.2" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 8181752, 20011599, 23721735, 29089431; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="glycine decarboxylase (subunit 1) (glycine cleavage system protein P)" /protein_id="NP_390336.2" /db_xref="EnsemblGenomes-Gn:BSU24560" /db_xref="EnsemblGenomes-Tr:CAB14387" /db_xref="GOA:P54376" /db_xref="InterPro:IPR015421" /db_xref="InterPro:IPR015422" /db_xref="InterPro:IPR015424" /db_xref="InterPro:IPR020581" /db_xref="InterPro:IPR023010" /db_xref="SubtiList:BG11510" /db_xref="UniProtKB/Swiss-Prot:P54376" /translation="MKHRYLPATEKDKQEMLATIGVSSIDDLFADIPENVKYKKEHQI KKAKSETELTRELTKLASKNRDTVQYASFLGAGVYDHYQPVIVDHVISRSEFYTAYTP YQPEISQGELQAIFEFQTMICELTGMDIANSSMYDGGTALAEAAMLASGHTKKKKIVV SKTVHPESREVLKTYAKGQYIDVVEVPAADGVTDLDALRQTVCENTAAVIVQYPNFFG RIEPLKDIEPIAHQGKSMFIVSANPLALGLLTPPGKFQSDIVVGDAQPFGIPSAYGGP HCGFFAVTKKLMRKVPGRLVGQTEDENGKRGFVLTLQAREQHIRRDKATSNICSNQAL NALAASVAMTALGKNGVKDIARQNLLKANYAKQEAKKAGLTVMFDGPMFNEFVIKLDE PVRAVNKRLLAKGMIGGYDLGLTYPELDCHMLIAVTELRTKEEIDALIQELGDRHE*" gene complement(2412467..2413813) /gene="gcvPA" /locus_tag="BSU_24560" /old_locus_tag="BSU24560" CDS complement(2413843..2414931) /gene="gcvT" /locus_tag="BSU_24570" /old_locus_tag="BSU24570" /EC_number="2.1.2.10" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:8219277, 15472076, 22720735, 23721735, 29089431" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8219277, 15472076, 22720735, 23721735, 29089431; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="aminomethyltransferase (glycine cleavage system protein T)" /protein_id="NP_390337.2" /db_xref="EnsemblGenomes-Gn:BSU24570" /db_xref="EnsemblGenomes-Tr:CAB14388" /db_xref="GOA:P54378" /db_xref="InterPro:IPR006222" /db_xref="InterPro:IPR006223" /db_xref="InterPro:IPR013977" /db_xref="InterPro:IPR022903" /db_xref="InterPro:IPR028896" /db_xref="InterPro:IPR029043" /db_xref="PDB:1YX2" /db_xref="SubtiList:BG11509" /db_xref="UniProtKB/Swiss-Prot:P54378" /translation="MLKRTPLFDLYKEYGGKTIDFGGWELPVQFSSIKKEHEAVRTAA GLFDVSHMGEVEVSGNDSLSFLQRLMTNDVSALTPGRAQYTAMCYPDGGTVDDLLIYQ KGENRYLLVINASNIDKDLAWMKEHAAGDVQIDNQSDQIALLAVQGPKAEAILKNLTD ADVSALKPFAFIDEADISGRKALISRTGYTGEDGYEIYCRSDDAMHIWKKIIDAGDAY GLIPCGLGARDTLRFEAKLPLYGQELTRDITPIEAGIGFAVKHKKESDFFGKSVLSEQ KENGAKRKLVGLEMIEKGIPRHGYEVFQNGKSVGKVTTGTQSPTLGKNVGLALIDSET SEIGTVVDVEIRKKLVKAKVVKTPFYKR*" gene complement(2413843..2414931) /gene="gcvT" /locus_tag="BSU_24570" /old_locus_tag="BSU24570" misc_RNA complement(2415005..2415204) /gene="swgA" /locus_tag="BSU_misc_RNA_37" /product="dual aptamer glycine riboswitch" /experiment="publication(s) with functional evidences, PMID:15472076, 21439473, 23249744, 23721735, 29089431" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15472076, 21439473, 23249744, 23721735, 29089431; Product type n: RNA" gene complement(2415005..2415204) /gene="swgA" /locus_tag="BSU_misc_RNA_37" downshifts complement(2415055) /Source="Nicolas_upshifts" /id="D1277" /incds=0 /nref=1 /ntot=31 /MaxReadThrough="6.79606" /MaxDrop="3.0322" /score="21.5485037" /energy="-20.2" /TU="U1911" /idTUdmin="U1915" /TUdmin=3630 /isTUend="FALSE" S_feature complement(2415205..2415275) /Source="Nicolas_S_feature" /locus_tag="new_2549607_2549677_c" /HighExp="B60, S8, S6, B36, S7, M9-stat, Sw, T3.0H, HiOs, M40t90" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.995" /TUlongSig="NA" /TUlongPSig="NA" /label="S922" promotor_-35 2415208..2415213 /Source="Nicolas_upshift_promotors" /id="U1910" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.83016983016983" /psig="0.83016983016983" /xcortree=1074 /SigmaFactorBS="gttttcggtcaggtctctccccttgctgtcattcgCTCATAt tttcatgctgttatGGACATACTATAGCAATATcttacatcaaatacatactcatatc c" /listShort="S923, yqhH, yqhG, S924, sinI, sinR" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2415229..2415247 /Source="Nicolas_upshift_promotors" /id="U1910" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.83016983016983" /psig="0.83016983016983" /xcortree=1074 /SigmaFactorBS="gttttcggtcaggtctctccccttgctgtcattcgCTCATAt tttcatgctgttatGGACATACTATAGCAATATcttacatcaaatacatactcatatc c" /listShort="S923, yqhH, yqhG, S924, sinI, sinR" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2415233 /Source="Nicolas_upshifts" /id="U1910" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.83016983016983" /psig="0.83016983016983" /xcortree=1074 /SigmaFactorBS="gttttcggtcaggtctctccccttgctgtcattcgCTCATAt tttcatgctgttatGGACATACTATAGCAATATcttacatcaaatacatactcatatc c" /listShort="S923, yqhH, yqhG, S924, sinI, sinR" /GFF_Attribute="listLong" S_feature 2415243..2415372 /Source="Nicolas_S_feature" /locus_tag="new_2549645_2549774" /HighExp="S4, S8, S7, S3, S5, S6, LoTm, T5.0H, T4.0H, C30" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigEF" /TUshortPSig="0.83" /TUlongSig="NA" /TUlongPSig="NA" /label="S923" promotor_-10 complement(2415261..2415280) /Source="Nicolas_upshift_promotors" /id="U1911" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.629370629370629" /psig="0.995004995004995" /xcortree=417 /SigmaFactorBS="gatgaataatataagaaaaatctgcccaaattgcTGTTGCCC agcatatagtgatGATGGTAGGATATGAGTATGtatttgatgtaagatattgctatag t" /listShort="S922, NA, NA, gcvT, gcvPA, gcvPB, S920, yqhM" /listLong="mntR" /label="promotor_-10" upshifts complement(2415275) /Source="Nicolas_upshifts" /id="U1911" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.629370629370629" /psig="0.995004995004995" /xcortree=417 /SigmaFactorBS="gatgaataatataagaaaaatctgcccaaattgcTGTTGCCC agcatatagtgatGATGGTAGGATATGAGTATGtatttgatgtaagatattgctatag t" /listShort="S922, NA, NA, gcvT, gcvPA, gcvPB, S920, yqhM" /listLong="mntR" promotor_-35 complement(2415294..2415301) /Source="Nicolas_upshift_promotors" /id="U1911" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.629370629370629" /psig="0.995004995004995" /xcortree=417 /SigmaFactorBS="gatgaataatataagaaaaatctgcccaaattgcTGTTGCCC agcatatagtgatGATGGTAGGATATGAGTATGtatttgatgtaagatattgctatag t" /listShort="S922, NA, NA, gcvT, gcvPA, gcvPB, S920, yqhM" /listLong="mntR" /label="promotor_-35" CDS 2415373..2417046 /gene="yqhH" /locus_tag="BSU_24580" /old_locus_tag="BSU24580" /EC_number="3.6.-.-" /function="16.3: Control" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 26735940; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative RNA polymerase-associated helicase protein" /protein_id="NP_390338.1" /db_xref="EnsemblGenomes-Gn:BSU24580" /db_xref="EnsemblGenomes-Tr:CAB14389" /db_xref="GOA:P54509" /db_xref="InterPro:IPR000330" /db_xref="InterPro:IPR001650" /db_xref="InterPro:IPR014001" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG11699" /db_xref="UniProtKB/Swiss-Prot:P54509" /translation="MNTEMIYDAKWPEEFAERLKNDGPWANWELYKLSAEIQKTLAIP EFEGLRAPLYLPSFTPLPHQLEVAQKVVEKMNGKAILADEVGLGKTVEAGLILKEYMI RGLAKKILILVPASLVSQWVKELQEKFLIPAVEQKKSYVWEQCDIVVSSIDTAKRSPH REIVLSIPYDLVIIDEAHKLKNSKTKNYEFVRNLVKKYCLLLTATPIQNRIEEIFNLV SLLKPGHLGSQNHFQEEFAKKKSSLEAHEHLKDLVNKVMIRNRRHDTGLNWKQRHVET VPIQFSPSEQALYDEISRLKDSINKPASMFSIMTLQRECCSSREAVYMTLKKMLDQKE KQAPAIDEDTISVLIDRINQVTQNSKALQVVDLIKKIDDKVIIFTEYRATQIYLQWFL QQNGISSVPFRGGFKRGKKDWMKDLFRGKIQVLIATEAGGEGINLQFCNHMINYDLPW NPMRLEQRIGRIHRLGQERDVHIYNMATKHTVEEHILKLLYEKIHLFEKVVGELDDIL TKIQVNNFEEHLHDILYHSATEEEMKIKMDNLTSFLSYKKQLPAEKRGS*" gene 2415373..2417046 /gene="yqhH" /locus_tag="BSU_24580" /old_locus_tag="BSU24580" CDS 2417067..2417861 /gene="yqhG" /locus_tag="BSU_24590" /old_locus_tag="BSU24590" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_390339.1" /db_xref="EnsemblGenomes-Gn:BSU24590" /db_xref="EnsemblGenomes-Tr:CAB14390" /db_xref="InterPro:IPR024562" /db_xref="SubtiList:BG11698" /db_xref="UniProtKB/Swiss-Prot:P54508" /translation="MRQQEVHDFLLRFFQANSCQIVDQGLGYMTVQLTVEMDKQIMNR PFYWHWREKTGGDPNPMKITFITDKENAPKDLDGEFIYFGAPRLFQIFKAVKQNGRFT RMYEKIESAGAKVPLQPWLGINVTISYQSDMKKDKLLSLGLHLVSGTIIEDFQSKLTQ FSLTSQICDYCFTISPMIKPESGLKRMENYISKSAMQEPSDWAEQAVNRWKNDMTLLD KFYEHIEEKPEEYHLEKQALKTLYQPKISVEIENGGLFYLQNNISS*" gene 2417067..2417861 /gene="yqhG" /locus_tag="BSU_24590" /old_locus_tag="BSU24590" misc_feature 2417397..2417398 /Source="Nicolas_upshift_promotors" /id="U1912" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.497502497502497" /psig="0.541458541458541" /xcortree=3205 /SigmaFactorBS="aaagctgttaaacaaaatgggagatttaccagaatgtatgag aaaattgaatcaGCcggagctaaagtcccacttcagccttggcttggtataaatgtca c" /GFF_Attribute="listShort" /listLong="S924, sinI, sinR" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 2417403 /Source="Nicolas_upshifts" /id="U1912" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.497502497502497" /psig="0.541458541458541" /xcortree=3205 /SigmaFactorBS="aaagctgttaaacaaaatgggagatttaccagaatgtatgag aaaattgaatcaGCcggagctaaagtcccacttcagccttggcttggtataaatgtca c" /GFF_Attribute="listShort" /listLong="S924, sinI, sinR" promotor_-35 2417885..2417888 /Source="Nicolas_upshift_promotors" /id="U1913" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.667332667332667" /psig="0.843156843156843" /xcortree=965 /SigmaFactorBS="ataatatttcaagctaacttttttaccattcgacatcattCT CGttttttttgagaaaaTACGATTATAATAAAGGTATattggaaaaaaattctggtga t" /listShort="S924, sinI, sinR" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2417904..2417923 /Source="Nicolas_upshift_promotors" /id="U1913" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.667332667332667" /psig="0.843156843156843" /xcortree=965 /SigmaFactorBS="ataatatttcaagctaacttttttaccattcgacatcattCT CGttttttttgagaaaaTACGATTATAATAAAGGTATattggaaaaaaattctggtga t" /listShort="S924, sinI, sinR" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 2417905..2418043 /Source="Nicolas_S_feature" /locus_tag="new_2552307_2552445" /HighExp="LoTm, S4, S5, T5.0H, M9-stat, S3, B60, S7, T4.0H, T3.30H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigEF" /TUshortPSig="0.843, 0.83" /TUlongSig="SigA" /TUlongPSig="0.541" /label="S924" upshifts 2417905 /Source="Nicolas_upshifts" /id="U1913" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.667332667332667" /psig="0.843156843156843" /xcortree=965 /SigmaFactorBS="ataatatttcaagctaacttttttaccattcgacatcattCT CGttttttttgagaaaaTACGATTATAATAAAGGTATattggaaaaaaattctggtga t" /listShort="S924, sinI, sinR" /GFF_Attribute="listLong" CDS 2418044..2418217 /gene="sinI" /locus_tag="BSU_24600" /old_locus_tag="BSU24600" /function="16.5: Explore" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:8549812, 10547280, 11751836, 15661000, 15805512, 23569226, 25326308, 26434553, 28430084" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8549812, 10547280, 11751836, 15661000, 15805512, 23569226, 25326308, 26434553, 28430084; Product type r: regulator" /codon_start=1 /transl_table=11 /product="antagonist of SinR" /protein_id="NP_390340.1" /db_xref="EnsemblGenomes-Gn:BSU24600" /db_xref="EnsemblGenomes-Tr:CAB14391" /db_xref="GOA:P23308" /db_xref="InterPro:IPR010981" /db_xref="InterPro:IPR036281" /db_xref="PDB:1B0N" /db_xref="SubtiList:BG10753" /db_xref="UniProtKB/Swiss-Prot:P23308" /translation="MKNAKQEHFELDQEWVELMVEAKEANISPEEIRKYLLLNKKSAH PGPAARSHTVNPF*" gene 2418044..2418217 /gene="sinI" /locus_tag="BSU_24600" /old_locus_tag="BSU24600" promotor_-35 2418202..2418206 /Source="Nicolas_upshift_promotors" /id="U1914" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.995004995004995" /psig=1 /xcortree=3096 /SigmaFactorBS="acaaaaagtctgctcatcctggtccggcagccagaagtcata cCGTAAatcctttctgaaTGTGCTATAATATCACAAGGaaggtgatgacattgattgg c" /listShort="sinR" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2418219..2418238 /Source="Nicolas_upshift_promotors" /id="U1914" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.995004995004995" /psig=1 /xcortree=3096 /SigmaFactorBS="acaaaaagtctgctcatcctggtccggcagccagaagtcata cCGTAAatcctttctgaaTGTGCTATAATATCACAAGGaaggtgatgacattgattgg c" /listShort="sinR" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2418219 /Source="Nicolas_upshifts" /id="U1914" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.995004995004995" /psig=1 /xcortree=3096 /SigmaFactorBS="acaaaaagtctgctcatcctggtccggcagccagaagtcata cCGTAAatcctttctgaaTGTGCTATAATATCACAAGGaaggtgatgacattgattgg c" /listShort="sinR" /GFF_Attribute="listLong" CDS 2418251..2418586 /gene="sinR" /locus_tag="BSU_24610" /old_locus_tag="BSU24610" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:15805512, 16585769, 16740951, 16923912, 21708175, 25326308, 26434553, 28546427" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15805512, 16585769, 16740951, 16923912, 21708175, 25326308, 26434553, 28546427; Product type r: regulator" /codon_start=1 /transl_table=11 /product="master regulator of biofilm formation" /protein_id="NP_390341.1" /db_xref="EnsemblGenomes-Gn:BSU24610" /db_xref="EnsemblGenomes-Tr:CAB14392" /db_xref="GOA:P06533" /db_xref="InterPro:IPR001387" /db_xref="InterPro:IPR010981" /db_xref="InterPro:IPR010982" /db_xref="InterPro:IPR036281" /db_xref="PDB:1B0N" /db_xref="PDB:2YAL" /db_xref="PDB:3QQ6" /db_xref="PDB:3ZKC" /db_xref="SubtiList:BG10754" /db_xref="UniProtKB/Swiss-Prot:P06533" /translation="MIGQRIKQYRKEKGYSLSELAEKAGVAKSYLSSIERNLQTNPSI QFLEKVSAVLDVSVHTLLDEKHETEYDGQLDSEWEKLVRDAMTSGVSKKQFREFLDYQ KWRKSQKEE*" gene 2418251..2418586 /gene="sinR" /locus_tag="BSU_24610" /old_locus_tag="BSU24610" downshifts 2418563 /Source="Nicolas_upshifts" /id="D1278" /incds=0 /nref=21 /ntot=181 /MaxReadThrough="4.7611" /MaxDrop="6.41889" /score="2.30357781" /energy="-20" /TU="U1913,U1914" /idTUdmin="U1910" /TUdmin="-2" /isTUend="TRUE" downshifts 2418653 /Source="Nicolas_upshifts" /id="D1279" /incds=0 /nref=1 /ntot=85 /MaxReadThrough="2.4376" /MaxDrop="4.25363" /score="58.1462301" /energy="-26.8" /TU="NA" /idTUdmin="U1913" /TUdmin=22 /isTUend="TRUE" CDS complement(2418679..2419464) /gene="tasA" /locus_tag="BSU_24620" /old_locus_tag="BSU24620" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:10464223, 10827084, 16430695, 16430696, 18047568, 23569226, 25326308, 27655338, 28546427" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10464223, 10827084, 16430695, 16430696, 18047568, 23569226, 25326308, 27655338, 28546427; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="major biofilm matrix component" /protein_id="NP_390342.1" /db_xref="EnsemblGenomes-Gn:BSU24620" /db_xref="EnsemblGenomes-Tr:CAB14393" /db_xref="GOA:P54507" /db_xref="InterPro:IPR022121" /db_xref="InterPro:IPR023833" /db_xref="SubtiList:BG11697" /db_xref="UniProtKB/Swiss-Prot:P54507" /translation="MGMKKKLSLGVASAALGLALVGGGTWAAFNDIKSKDATFASGTL DLSAKENSASVNLSNLKPGDKLTKDFQFENNGSLAIKEVLMALNYGDFKANGGSNTSP EDFLSQFEVTLLTVGKEGGNGYPKNIILDDANLKDLYLMSAKNDAAAAEKIKKQIDPK FLNASGKVNVATIDGKTAPEYDGVPKTPTDFDQVQMEIQFKDDKTKDEKGLMVQNKYQ GNSIKLQFSFEATQWNGLTIKKDHTDKDGYVKENEKAHSEDKN*" gene complement(2418679..2419464) /gene="tasA" /locus_tag="BSU_24620" /old_locus_tag="BSU24620" downshifts complement(2418685) /Source="Nicolas_upshifts" /id="D1280" /incds=0 /nref=144 /ntot=227 /MaxReadThrough="4.33009" /MaxDrop="8.70948" /score="10.0483516" /energy="-20" /TU="NA" /idTUdmin="U1915" /TUdmin=0 /isTUend="TRUE" misc_feature complement(2419517..2419534) /Source="Nicolas_upshift_promotors" /id="U1915" /multdbtbs="-" /comp="M14" /sig="Sig-" /pcomp="0.236763236763237" /psig="0.478521478521479" /xcortree=2768 /SigmaFactorBS="agaaagacaaaagccttggaaacagatacaaaggacagcacc atgtcTACTTAACTTCAGTTGTAaacctggcaacaggtttcgatataaaatcattcaa t" /listShort="tasA" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(2419521) /Source="Nicolas_upshifts" /id="U1915" /multdbtbs="-" /comp="M14" /sig="Sig-" /pcomp="0.236763236763237" /psig="0.478521478521479" /xcortree=2768 /SigmaFactorBS="agaaagacaaaagccttggaaacagatacaaaggacagcacc atgtcTACTTAACTTCAGTTGTAaacctggcaacaggtttcgatataaaatcattcaa t" /listShort="tasA" /GFF_Attribute="listLong" CDS complement(2419528..2420100) /gene="sipW" /locus_tag="BSU_24630" /old_locus_tag="BSU24630" /EC_number="3.4.21.89" /function="16.1: Circulate" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:10464223, 10559173, 10827084, 15101989, 16430695, 22328672, 26346121, 27655338" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10464223, 10559173, 10827084, 15101989, 16430695, 22328672, 26346121, 27655338; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="type I signal peptidase" /protein_id="NP_390343.1" /db_xref="EnsemblGenomes-Gn:BSU24630" /db_xref="EnsemblGenomes-Tr:CAB14394" /db_xref="GOA:P54506" /db_xref="InterPro:IPR001733" /db_xref="InterPro:IPR015927" /db_xref="InterPro:IPR036286" /db_xref="SubtiList:BG11696" /db_xref="UniProtKB/Swiss-Prot:P54506" /translation="MKLISNILYVIIFTLIIVLTLVVISTRSSGGEPAVFGYTLKSVL SGSMEPEFNTGSLILVKEITDVKELQKGDVITFMQDANTAVTHRIVDITKQGDHLLFK TKGDNNAAADSAPVSDENVRAQYTGFQLPYAGYMLHFASQPIGTAVLLIVPGVMLLVY AFVTISSAIREIERKTKALETDTKDSTMST*" gene complement(2419528..2420100) /gene="sipW" /locus_tag="BSU_24630" /old_locus_tag="BSU24630" CDS complement(2420084..2420845) /gene="tapA" /locus_tag="BSU_24640" /old_locus_tag="BSU24640" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:10464223, 10559173, 14707086, 16430695, 17554552, 21477127, 24488317, 26441856, 26819068, 27655338" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10464223, 10559173, 14707086, 16430695, 17554552, 21477127, 24488317, 26441856, 26819068, 27655338; Product type lp : lipoprotein" /codon_start=1 /transl_table=11 /product="lipoprotein for biofilm formation" /protein_id="NP_390344.1" /db_xref="EnsemblGenomes-Gn:BSU24640" /db_xref="EnsemblGenomes-Tr:CAB14395" /db_xref="GOA:P40949" /db_xref="InterPro:IPR013783" /db_xref="InterPro:IPR023833" /db_xref="InterPro:IPR023848" /db_xref="SubtiList:BG11076" /db_xref="UniProtKB/Swiss-Prot:P40949" /translation="MFRLFHNQQKAKTKLKVLLIFQLSVIFSLTAAICLQFSDDTSAA FHDIETFDVSLQTCKDFQHTDKNCHYDKRWDQSDLHISDQTDTKGTVCSPFALFAVLE NTGEKLKKSKWKWELHKLENARKPLKDGNVIEKGFVSNQIGDSLYKIETKKKMKPGIY AFKVYKPAGYPANGSTFEWSEPMRLAKCDEKPTVPKKETKSDVKKENETTQKDIPEKT MKEETSQEAVTKEKETQSDQKESGEEDEKSNEADQ*" gene complement(2420084..2420845) /gene="tapA" /locus_tag="BSU_24640" /old_locus_tag="BSU24640" promotor_-10 complement(2420905..2420924) /Source="Nicolas_upshift_promotors" /id="U1916" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.473526473526474" /psig="0.97002997002997" /xcortree=2769 /SigmaFactorBS="aaaacattcttttaaacgaacaaaatgagcgatttcggTGTT TTTAaatctataaatcgTTGATTATACTCTATTTGTGaagttctttaaagagaacgat t" /listShort="yqxM, sipW" /listLong="tasA" /label="promotor_-10" upshifts complement(2420923) /Source="Nicolas_upshifts" /id="U1916" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.473526473526474" /psig="0.97002997002997" /xcortree=2769 /SigmaFactorBS="aaaacattcttttaaacgaacaaaatgagcgatttcggTGTT TTTAaatctataaatcgTTGATTATACTCTATTTGTGaagttctttaaagagaacgat t" /listShort="yqxM, sipW" /listLong="tasA" promotor_-35 complement(2420938..2420945) /Source="Nicolas_upshift_promotors" /id="U1916" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.473526473526474" /psig="0.97002997002997" /xcortree=2769 /SigmaFactorBS="aaaacattcttttaaacgaacaaaatgagcgatttcggTGTT TTTAaatctataaatcgTTGATTATACTCTATTTGTGaagttctttaaagagaacgat t" /listShort="yqxM, sipW" /listLong="tasA" /label="promotor_-35" promotor_-35 2421067..2421073 /Source="Nicolas_upshift_promotors" /id="U1917" /multdbtbs="SigF" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=1137 /SigmaFactorBS="ctcattttttcaattttttagaaatttttgggattgttatgt gagaatttaaaTGCATATcccattattatttGGTAATAATAAAcaaagaaagggtgac a" /listShort="yqzG" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 2421074 /Source="Nicolas_upshifts" /id="U1917" /multdbtbs="SigF" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=1137 /SigmaFactorBS="ctcattttttcaattttttagaaatttttgggattgttatgt gagaatttaaaTGCATATcccattattatttGGTAATAATAAAcaaagaaagggtgac a" /listShort="yqzG" /GFF_Attribute="listLong" promotor_-10 2421087..2421098 /Source="Nicolas_upshift_promotors" /id="U1917" /multdbtbs="SigF" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=1137 /SigmaFactorBS="ctcattttttcaattttttagaaatttttgggattgttatgt gagaatttaaaTGCATATcccattattatttGGTAATAATAAAcaaagaaagggtgac a" /listShort="yqzG" /GFF_Attribute="listLong" /label="promotor_-10" CDS 2421117..2421443 /gene="yqzG" /locus_tag="BSU_24650" /old_locus_tag="BSU24650" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type f: factor" /codon_start=1 /transl_table=11 /product="putative exported protein" /protein_id="NP_390345.1" /db_xref="EnsemblGenomes-Gn:BSU24650" /db_xref="EnsemblGenomes-Tr:CAB14396" /db_xref="InterPro:IPR024987" /db_xref="PDB:2LYX" /db_xref="SubtiList:BG13773" /db_xref="UniProtKB/Swiss-Prot:O32019" /translation="MMIKQCVICLSLLVFGTTAAHAEETPLVTARHMSKWEEIAVKEA KKRYPLAQVLFKQKVWDRKRKDEAVKQYHLTLREGSKEFGVFVTISFDPYSQKVNKIA ILEEYQ*" gene 2421117..2421443 /gene="yqzG" /locus_tag="BSU_24650" /old_locus_tag="BSU24650" S_feature complement(2421260..2421484) /Source="Nicolas_S_feature" /locus_tag="new_2555662_2555886_c" /HighExp="GM 150, G/S, C30, T-4.40H, S8, T-3.40H, Pyr, S7, S2, C90" /AntisenseName="yqzG" /AntisenseCor="0.536702817178903" /AntisenseRegPval="-20.7" /CDS_PredictionProba="NA" /TUshortSig="SigEF, SigA" /TUshortPSig="0.549, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S925" downshifts complement(2421303) /Source="Nicolas_upshifts" /id="D1281" /incds=1 /nref=92 /ntot=160 /MaxReadThrough="2.23218" /MaxDrop="5.56661" /score="31.27773" /energy="-10.2" /TU="NA" /idTUdmin="U1918" /TUdmin=0 /isTUend="TRUE" downshifts 2421425 /Source="Nicolas_upshifts" /id="D1282" /incds=0 /nref=13 /ntot=41 /MaxReadThrough="2.14107" /MaxDrop="4.98052" /score="-9.62570043" /energy="-15.1" /TU="NA" /idTUdmin="U1917" /TUdmin=0 /isTUend="TRUE" CDS complement(2421485..2421664) /gene="spoIIT" /locus_tag="BSU_24660" /old_locus_tag="BSU24660" /function="16.1: Circulate" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:26735940" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 26735940; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="factor involved in sporulation" /protein_id="NP_390346.2" /db_xref="EnsemblGenomes-Gn:BSU24660" /db_xref="EnsemblGenomes-Tr:CAB14397" /db_xref="InterPro:IPR025622" /db_xref="SubtiList:BG13771" /db_xref="UniProtKB/Swiss-Prot:O32020" /translation="MKTNDYVKYMTQQFVKYIDTPRDERKERKEVRKETKTPVSQQWF GILPYGFRLWLKRKK*" gene complement(2421485..2421664) /gene="spoIIT" /locus_tag="BSU_24660" /old_locus_tag="BSU24660" promotor_-10 complement(2421683..2421701) /Source="Nicolas_upshift_promotors" /id="U1918" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.549450549450549" /psig="0.549450549450549" /xcortree=1011 /SigmaFactorBS="aaactgctgagatggacagaataaaacagtgtaaagGGTATA AaaaaagtcatgtgaGACAACACTCATAATAATTgaatgatgaggtgatcacgtgaaa a" /listShort="yqzE, S925" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2421698) /Source="Nicolas_upshifts" /id="U1918" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.549450549450549" /psig="0.549450549450549" /xcortree=1011 /SigmaFactorBS="aaactgctgagatggacagaataaaacagtgtaaagGGTATA AaaaaagtcatgtgaGACAACACTCATAATAATTgaatgatgaggtgatcacgtgaaa a" /listShort="yqzE, S925" /GFF_Attribute="listLong" promotor_-35 complement(2421716..2421722) /Source="Nicolas_upshift_promotors" /id="U1918" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.549450549450549" /psig="0.549450549450549" /xcortree=1011 /SigmaFactorBS="aaactgctgagatggacagaataaaacagtgtaaagGGTATA AaaaaagtcatgtgaGACAACACTCATAATAATTgaatgatgaggtgatcacgtgaaa a" /listShort="yqzE, S925" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2421735..2422109) /gene="comGG" /locus_tag="BSU_24670" /old_locus_tag="BSU24670" /function="16.5: Explore" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:9150204, 9723928, 15849754, 16850406, 24164455" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9150204, 9723928, 15849754, 16850406, 24164455; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="component of the DNA transport pilin platform" /protein_id="NP_390347.1" /db_xref="EnsemblGenomes-Gn:BSU24670" /db_xref="EnsemblGenomes-Tr:CAB14398" /db_xref="GOA:P25959" /db_xref="InterPro:IPR020372" /db_xref="SubtiList:BG10489" /db_xref="UniProtKB/Swiss-Prot:P25959" /translation="MYRTRGFIYPAVLFVSALVLLIVNFVAAQYISRCMFEKETKELY IGENLLQNGVLLSIRHVLEERKGQEGTQQFLYGRVSYYIHDTSIKEQKEINLRVSTDS GTERTAQIVFDQKQKKLLRWTE*" gene complement(2421735..2422109) /gene="comGG" /locus_tag="BSU_24670" /old_locus_tag="BSU24670" CDS complement(2422110..2422493) /gene="comGF" /locus_tag="BSU_24680" /old_locus_tag="BSU24680" /function="16.5: Explore" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:9150204, 9723928, 15849754, 16850406" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9150204, 9723928, 15849754, 16850406; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="component of the DNA transport pilin platform" /protein_id="NP_390348.1" /db_xref="EnsemblGenomes-Gn:BSU24680" /db_xref="EnsemblGenomes-Tr:CAB14399" /db_xref="GOA:P25958" /db_xref="InterPro:IPR016977" /db_xref="SubtiList:BG10488" /db_xref="UniProtKB/Swiss-Prot:P25958" /translation="MLISGSLAAIIHLFLSRQQEHDGFTQQEWMISIEQMMNECKESQ AVKTAEHGSVLICTNLSGQDIRFDIYHSMIRKRVDGKGHVPILDHITAMKADIENGVV LLKIESEDQKVYQTAFPVYSYLGGG*" gene complement(2422110..2422493) /gene="comGF" /locus_tag="BSU_24680" /old_locus_tag="BSU24680" CDS complement(2422519..2422866) /gene="comGE" /locus_tag="BSU_24690" /old_locus_tag="BSU24690" /function="16.11: Scavenge (Catabolism)" /function="16.9: Replicate" /experiment="publication(s) with functional evidences, PMID:7783624, 9224890, 9422590, 9723928, 16751195" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7783624, 9224890, 9422590, 9723928, 16751195; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="component of the DNA transport pilin platform" /protein_id="NP_390349.1" /db_xref="EnsemblGenomes-Gn:BSU24690" /db_xref="EnsemblGenomes-Tr:CAB14400" /db_xref="GOA:P25957" /db_xref="InterPro:IPR012902" /db_xref="InterPro:IPR020488" /db_xref="SubtiList:BG10487" /db_xref="UniProtKB/Swiss-Prot:P25957" /translation="MWRENKGFSTIETMSALSLWLFVLLTVVPLWDKLMADEKMAESR EIGYQMMNESISKYVMSGEGAASKTITKNNHIYAMKWEEEGEYQNVCIKAAAYKEKSF CLSILQTEWLHAS*" gene complement(2422519..2422866) /gene="comGE" /locus_tag="BSU_24690" /old_locus_tag="BSU24690" CDS complement(2422850..2423281) /gene="comGD" /locus_tag="BSU_24700" /old_locus_tag="BSU24700" /function="16.5: Explore" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:9224890, 9422590, 9723928, 16751195" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9224890, 9422590, 9723928, 16751195; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="membrane component of the DNA transport pilin platform" /protein_id="NP_390350.1" /db_xref="EnsemblGenomes-Gn:BSU24700" /db_xref="EnsemblGenomes-Tr:CAB14401" /db_xref="GOA:P25956" /db_xref="InterPro:IPR002416" /db_xref="InterPro:IPR012902" /db_xref="InterPro:IPR016785" /db_xref="SubtiList:BG10486" /db_xref="UniProtKB/Swiss-Prot:P25956" /translation="MNIKLNEEKGFTLLESLLVLSLASILLVAVFTTLPPAYDNTAVR QAASQLKNDIMLTQQTAISRQQRTKILFHKKEYQLVIGDTVIERPYATGLSIELLTLK DRLEFNEKGHPNAGGKIRVKGHAVYDITVYLGSGRVNVERK*" gene complement(2422850..2423281) /gene="comGD" /locus_tag="BSU_24700" /old_locus_tag="BSU24700" CDS complement(2423271..2423567) /gene="comGC" /locus_tag="BSU_24710" /old_locus_tag="BSU24710" /function="16.11: Scavenge (Catabolism)" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:7783624, 9723928, 11744713, 16751195, 22820325, 24164455, 28659339" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7783624, 9723928, 11744713, 16751195, 22820325, 24164455, 28659339; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="pilin-like component of the DNA transport membrane pilin platform" /protein_id="NP_390351.1" /db_xref="EnsemblGenomes-Gn:BSU24710" /db_xref="EnsemblGenomes-Tr:CAB14402" /db_xref="GOA:P25955" /db_xref="InterPro:IPR012902" /db_xref="InterPro:IPR016940" /db_xref="SubtiList:BG10485" /db_xref="UniProtKB/Swiss-Prot:P25955" /translation="MNEKGFTLVEMLIVLFIISILLLITIPNVTKHNQTIQKKGCEGL QNMVKAQMTAFELDHEGQTPSLADLQSEGYVKKDAVCPNGKRIIITGGEVKVEH*" gene complement(2423271..2423567) /gene="comGC" /locus_tag="BSU_24710" /old_locus_tag="BSU24710" CDS complement(2423581..2424552) /gene="comGB" /locus_tag="BSU_24720" /old_locus_tag="BSU24720" /function="16.11: Scavenge (Catabolism)" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:9150204, 9723928, 15849754, 15968048, 16850406, 24164455" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9150204, 9723928, 15849754, 15968048, 16850406, 24164455; Product type cp : cell process" /codon_start=1 /transl_table=11 /product="membrane pilin platform component of the DNA transport machinery" /protein_id="NP_390352.1" /db_xref="EnsemblGenomes-Gn:BSU24720" /db_xref="EnsemblGenomes-Tr:CAB14403" /db_xref="GOA:P25954" /db_xref="InterPro:IPR001992" /db_xref="InterPro:IPR018076" /db_xref="SubtiList:BG10484" /db_xref="UniProtKB/Swiss-Prot:P25954" /translation="MTAGGYTLLDGLRLMELQMNKRQAADLTDSVTCLREGAPFYQVL KSLSFHKEAVGICYFAETHGELPASMIQSGELLERKIAQADQLKRVLRYPLFLIFTVA VMFYMLQSIIIPQFSGIYQSMNMETSRSTDMLFAFFQHIDLVIILLVLFTAGIGIYYW LVFKKKSPARQMLICIRIPLVGKLVKLFNSYFFSLQLSSLLKSGLSIYDSLNAFKHQT FLPFYRCEAEQLIERLKAGESIESAICGSLFYETDLSKVISHGQLSGRLDRELFTYSQ FILQRLEHKAQKWTGILQPMIYGFVAAMILLVYLSMLVPMYQMMNQM*" gene complement(2423581..2424552) /gene="comGB" /locus_tag="BSU_24720" /old_locus_tag="BSU24720" CDS complement(2424605..2425675) /gene="comGA" /locus_tag="BSU_24730" /old_locus_tag="BSU24730" /function="16.5: Explore" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:11298275, 15528548, 16009134, 9723928, 21564336, 21707789, 25899641" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11298275, 15528548, 16009134, 9723928, 21564336, 21707789, 25899641; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="membrane associated ATPase of the pilin platformfor DNA competence" /protein_id="NP_390353.1" /db_xref="EnsemblGenomes-Gn:BSU24730" /db_xref="EnsemblGenomes-Tr:CAB14404" /db_xref="GOA:P25953" /db_xref="InterPro:IPR001482" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG10483" /db_xref="UniProtKB/Swiss-Prot:P25953" /translation="MDSIEKVSKNLIEEAYLTKASDIHIVPRERDAIIHFRVDHALLK KRDMKKEECVRLISHFKFLSAMDIGERRKPQNGSLTLKLKEGNVHLRMSTLPTINEES LVIRVMPQYNIPSIDKLSLFPKTGATLLSFLKHSHGMLIFTGPTGSGKTTTLYSLVQY AKKHFNRNIVTLEDPVETRDEDVLQVQVNEKAGVTYSAGLKAILRHDPDMIILGEIRD AETAEIAVRAAMTGHLVLTSLHTRDAKGAIYRLLEFGINMNEIEQTVIAIAAQRLVDL ACPFCENGCSSVYCRQSRNTRRASVYELLYGKNLQQCIQEAKGNHANYQYQTLRQIIR KGIALGYLTTNNYDRWVYHEKD*" gene complement(2424605..2425675) /gene="comGA" /locus_tag="BSU_24730" /old_locus_tag="BSU24730" promotor_-10 complement(2425693..2425712) /Source="Nicolas_upshift_promotors" /id="U1919" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.943056943056943" /psig=1 /xcortree=2966 /SigmaFactorBS="ttcagcatataacatctcacaaaatcacgttttcccTGTTTG ATtaccttttcttctTTTTCTACAATATGCGTTGAaaggagagggaatcaaattggat t" /listShort="comGA, comGB, comGC, comGD, comGE, comGF, comGG, yqzE, S925" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2425709) /Source="Nicolas_upshifts" /id="U1919" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.943056943056943" /psig=1 /xcortree=2966 /SigmaFactorBS="ttcagcatataacatctcacaaaatcacgttttcccTGTTTG ATtaccttttcttctTTTTCTACAATATGCGTTGAaaggagagggaatcaaattggat t" /listShort="comGA, comGB, comGC, comGD, comGE, comGF, comGG, yqzE, S925" /GFF_Attribute="listLong" promotor_-35 complement(2425726..2425733) /Source="Nicolas_upshift_promotors" /id="U1919" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.943056943056943" /psig=1 /xcortree=2966 /SigmaFactorBS="ttcagcatataacatctcacaaaatcacgttttcccTGTTTG ATtaccttttcttctTTTTCTACAATATGCGTTGAaaggagagggaatcaaattggat t" /listShort="comGA, comGB, comGC, comGD, comGE, comGF, comGG, yqzE, S925" /GFF_Attribute="listLong" /label="promotor_-35" S_feature complement(2425858..2426086) /Source="Nicolas_S_feature" /locus_tag="new_2560260_2560488_c" /HighExp="Etha, Salt, Sw, Gly, LPhT, B36, Heat, B60, LoTm, M9-stat" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.37350499999999998" /TUshortSig="SigB" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S926" downshifts complement(2425899) /Source="Nicolas_upshifts" /id="D1283" /incds=0 /nref=16 /ntot=42 /MaxReadThrough="0.95925" /MaxDrop="5.92871" /score="30.7083619" /energy="-13" /TU="NA" /idTUdmin="U1920" /TUdmin=1 /isTUend="TRUE" CDS complement(2426087..2427040) /gene="yqxL" /locus_tag="BSU_24740" /old_locus_tag="BSU24740" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:15856219, 24415722" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15856219, 24415722; Product type t: transporter" /codon_start=1 /transl_table=11 /product="CorA-type divalent ion transporter" /protein_id="NP_390354.1" /db_xref="EnsemblGenomes-Gn:BSU24740" /db_xref="EnsemblGenomes-Tr:CAB14405" /db_xref="GOA:P40948" /db_xref="InterPro:IPR002523" /db_xref="SubtiList:BG11075" /db_xref="UniProtKB/Swiss-Prot:P40948" /translation="MKAHTGKDWFWYQMGPQERSKARDLIHFSHWPQCEKWFENNHHV NFLRVDTTETENEAVFGSIVYDQGLGEEKDHTVFHFYITRQYFFTINFDFSILREIKG KEVVRQMERADNAIEGFLILLGELMNAYLIGVDEFEVKLRKLRWQIKDDNSKSILNRV HLLRHELMIWKNLILSAKKIEMALKETFLPQNEGKKDYQRTQLKIDRGFTYISEFEGE LNNLLHSEEVITSHRGNEIVKALTIFTTLFTPITALGALWGMNFSVMPELNWKYGYLF SLLLIVTSTVLIYLYLRKKGWTGDMLQERKKKKKPRKRRTL*" gene complement(2426087..2427040) /gene="yqxL" /locus_tag="BSU_24740" /old_locus_tag="BSU24740" promotor_-10 complement(2427064..2427083) /Source="Nicolas_upshift_promotors" /id="U1920" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=239 /SigmaFactorBS="cacctgaaaatgctcataaaacatgtgttgaagcggcagact GGTTTAGtgacgcggttattGGGCAATTAAAGAATAAAGAacaaaagtttggaggagc t" /listShort="yqxL, S926" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2427085) /Source="Nicolas_upshifts" /id="U1920" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=239 /SigmaFactorBS="cacctgaaaatgctcataaaacatgtgttgaagcggcagact GGTTTAGtgacgcggttattGGGCAATTAAAGAATAAAGAacaaaagtttggaggagc t" /listShort="yqxL, S926" /GFF_Attribute="listLong" promotor_-35 complement(2427097..2427103) /Source="Nicolas_upshift_promotors" /id="U1920" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=239 /SigmaFactorBS="cacctgaaaatgctcataaaacatgtgttgaagcggcagact GGTTTAGtgacgcggttattGGGCAATTAAAGAATAAAGAacaaaagtttggaggagc t" /listShort="yqxL, S926" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 2427123..2427129 /Source="Nicolas_upshift_promotors" /id="U1921" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=246 /SigmaFactorBS="ccagtctgccgcttcaacacaTGTTTTAtgagcattttcagg TGGTATGGAATGTAGAAAGacatcggaaaagggaggtgcatgccttccttggagaagg c" /listShort="yqhB, S927" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2427144..2427162 /Source="Nicolas_upshift_promotors" /id="U1921" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=246 /SigmaFactorBS="ccagtctgccgcttcaacacaTGTTTTAtgagcattttcagg TGGTATGGAATGTAGAAAGacatcggaaaagggaggtgcatgccttccttggagaagg c" /listShort="yqhB, S927" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2427162 /Source="Nicolas_upshifts" /id="U1921" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=246 /SigmaFactorBS="ccagtctgccgcttcaacacaTGTTTTAtgagcattttcagg TGGTATGGAATGTAGAAAGacatcggaaaagggaggtgcatgccttccttggagaagg c" /listShort="yqhB, S927" /GFF_Attribute="listLong" CDS 2427183..2428511 /gene="yqhB" /locus_tag="BSU_24750" /old_locus_tag="BSU24750" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative membrane associated enzyme" /protein_id="NP_390355.1" /db_xref="EnsemblGenomes-Gn:BSU24750" /db_xref="EnsemblGenomes-Tr:CAB14406" /db_xref="GOA:P54505" /db_xref="InterPro:IPR000644" /db_xref="InterPro:IPR002550" /db_xref="InterPro:IPR005170" /db_xref="InterPro:IPR016169" /db_xref="InterPro:IPR036318" /db_xref="SubtiList:BG11695" /db_xref="UniProtKB/Swiss-Prot:P54505" /translation="MPSLEKAVVLEFINLLAVAILILLTGFFVAVEFSIVKVRRSKID QLVAKGKKGAKAAKHVITHLDEYLSACQLGITVAALGLGWLGEPTVQTLLRPLFHKAG LNESLTHLLSLVIAFLVVTYLNVVIGELAPKSFAIQKAESITLLFAKPLIWFYKIMFP FIWLLNHSARLITGVFGLKPASEHELAYTEEELRVLLAESYKSGEIRKSELKYMNNIF TFDKRMAKEIMVPRNEMVSLSLDEDSISNLQETVKQTKYTRYPVVREDKDNVIGVINM KEVLFSMLTKDFSIKKHQIEPFVQPVIHVIETIPIYKLLLKMQKERTHMAILIDEYGG TSGLVTVEDIIEEIVGEIRDEFDADEVPHIRELGKDHYLLNAKLLISDVNSLLGTDLS EAEVDTLGGWFLTQNIDAEPESAIEYDGYSFKVKDINSHHILFIEVKKAE*" gene 2427183..2428511 /gene="yqhB" /locus_tag="BSU_24750" /old_locus_tag="BSU24750" S_feature 2428512..2429486 /Source="Nicolas_S_feature" /locus_tag="new_2562914_2563888" /HighExp="Sw, Salt, Etha, LPhT, M9-stat, S8, BC, S6, BT, Gly" /AntisenseName="rsbRD" /AntisenseCor="0.58358076577781004" /AntisenseRegPval="-25.2" /CDS_PredictionProba="NA" /TUshortSig="SigB" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S927" CDS complement(2428564..2429400) /gene="rsbRD" /locus_tag="BSU_24760" /old_locus_tag="BSU24760" /function="16.3: Control" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:11157946, 15312768, 15583165, 16963570, 17158665" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11157946, 15312768, 15583165, 16963570, 17158665; Product type f: factor" /codon_start=1 /transl_table=11 /product="component of the anxiosome (stressosome)" /protein_id="NP_390356.2" /db_xref="EnsemblGenomes-Gn:BSU24760" /db_xref="EnsemblGenomes-Tr:CAB14407" /db_xref="InterPro:IPR002645" /db_xref="InterPro:IPR025751" /db_xref="InterPro:IPR036513" /db_xref="SubtiList:BG11694" /db_xref="UniProtKB/Swiss-Prot:P54504" /translation="MIALDQHLTEHKKDITQQWLEVCTSNGSWLYSAKDQQKLEQKLK DQHELLVTIVAKSLRKEDVEDELNRWSLQCARDRAVHEVTVTQSVGQFNTFRHIMFEW IHKFSEASSQDISIQEFYEWSRILNQNIDEIIEVFTEEYHQVTMIQLNAQKEMINELS APIMPITDGIGILPLVGEIDTHRARTILESVLEQCSALKLSYLFLDISGVPIVDTMVA YQIFKVIDSTKLLGIETIISGIRPEIAQTVVKLGLDFSNVKTEQSLAKALANKGFKIK EC*" gene complement(2428564..2429400) /gene="rsbRD" /locus_tag="BSU_24760" /old_locus_tag="BSU24760" S_feature complement(2429401..2429585) /Source="Nicolas_S_feature" /locus_tag="new_2563803_2563987_c" /HighExp="Etha, LoTm, Salt, Heat, Gly, M9-stat, B60, S8, S0, Mal" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.147982" /TUshortSig="SigB" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S928" tRNA 2429487..2429557 /gene="trnSL-Gln1" /locus_tag="BSU_tRNA_73" /product="tRNA-Gln" /inference="profile:tRNAscan:1.23" /note="transfer RNA-Gln (UUG); Evidence 2a: Function from experimental evidences in other organisms; Product type n: RNA" gene 2429487..2429557 /gene="trnSL-Gln1" /locus_tag="BSU_tRNA_73" CDS complement(2429624..2430004) /gene="mgsR" /locus_tag="BSU_24770" /old_locus_tag="BSU24770" /function="16.3: Control" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:18643936, 22812682" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 18643936, 22812682; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator of stress" /protein_id="NP_390357.2" /db_xref="EnsemblGenomes-Gn:BSU24770" /db_xref="EnsemblGenomes-Tr:CAB14408" /db_xref="GOA:P54503" /db_xref="InterPro:IPR006504" /db_xref="InterPro:IPR006660" /db_xref="InterPro:IPR036249" /db_xref="SubtiList:BG11693" /db_xref="UniProtKB/Swiss-Prot:P54503" /translation="MEQQLTFYSYPSCTSCRKTKHWLKAHQIEFNERHLFRETPTREE LKYILSLTTEGIDEILATRSQTFKNLNLNIEEMTVNEVLELLIEKPKLLRRPILVDNK KLVIGYNPGELLKLSKKKTVHQSA*" gene complement(2429624..2430004) /gene="mgsR" /locus_tag="BSU_24770" /old_locus_tag="BSU24770" downshifts complement(2429630) /Source="Nicolas_upshifts" /id="D1284" /incds=0 /nref=9 /ntot=174 /MaxReadThrough="6.12556" /MaxDrop="6.72616" /score="0.164931099" /energy="-19.7" /TU="U1922" /idTUdmin="U1925" /TUdmin=912 /isTUend="FALSE" promotor_-10 complement(2430033..2430051) /Source="Nicolas_upshift_promotors" /id="U1922" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=225 /SigmaFactorBS="aatgttttttaaaaaataatccgaaaaaagttctgtaaatGG TTTAAatgaaaaatgatccGGGTAGTTATTCTACAAAGagatggttaactgaggagga a" /listShort="mgsR, S928, rsbRD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2430052) /Source="Nicolas_upshifts" /id="U1922" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=225 /SigmaFactorBS="aatgttttttaaaaaataatccgaaaaaagttctgtaaatGG TTTAAatgaaaaatgatccGGGTAGTTATTCTACAAAGagatggttaactgaggagga a" /listShort="mgsR, S928, rsbRD" /GFF_Attribute="listLong" promotor_-35 complement(2430066..2430072) /Source="Nicolas_upshift_promotors" /id="U1922" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=225 /SigmaFactorBS="aatgttttttaaaaaataatccgaaaaaagttctgtaaatGG TTTAAatgaaaaatgatccGGGTAGTTATTCTACAAAGagatggttaactgaggagga a" /listShort="mgsR, S928, rsbRD" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 2430091..2430096 /Source="Nicolas_upshift_promotors" /id="U1923" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1002 /SigmaFactorBS="ttcatttaaaccatttacagaacttttttcGGATTAtttttt aaaaaacatTCATACAATAGAAAACACAatcaaagggacaaattccatttgtatatta a" /GFF_Attribute="listShort" /listLong="yqgY, S929, yqgW, S930" /label="promotor_-35" promotor_-10 2430112..2430130 /Source="Nicolas_upshift_promotors" /id="U1923" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1002 /SigmaFactorBS="ttcatttaaaccatttacagaacttttttcGGATTAtttttt aaaaaacatTCATACAATAGAAAACACAatcaaagggacaaattccatttgtatatta a" /GFF_Attribute="listShort" /listLong="yqgY, S929, yqgW, S930" /label="promotor_-10" upshifts 2430121 /Source="Nicolas_upshifts" /id="U1923" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1002 /SigmaFactorBS="ttcatttaaaccatttacagaacttttttcGGATTAtttttt aaaaaacatTCATACAATAGAAAACACAatcaaagggacaaattccatttgtatatta a" /GFF_Attribute="listShort" /listLong="yqgY, S929, yqgW, S930" promotor_-35 2430171..2430178 /Source="Nicolas_upshift_promotors" /id="U1924" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.845154845154845" /psig=1 /xcortree=513 /SigmaFactorBS="caaagggacaaattccatttgtatattaataatgaaaaTGTT TACAtttctaggtgtgatcTATTATAATAACAGTCAGAGggactctcgggaggggata a" /listShort="yqgY, S929" /listLong="yqgW, S930" /label="promotor_-35" upshifts 2430193 /Source="Nicolas_upshifts" /id="U1924" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.845154845154845" /psig=1 /xcortree=513 /SigmaFactorBS="caaagggacaaattccatttgtatattaataatgaaaaTGTT TACAtttctaggtgtgatcTATTATAATAACAGTCAGAGggactctcgggaggggata a" /listShort="yqgY, S929" /listLong="yqgW, S930" promotor_-10 2430194..2430213 /Source="Nicolas_upshift_promotors" /id="U1924" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.845154845154845" /psig=1 /xcortree=513 /SigmaFactorBS="caaagggacaaattccatttgtatattaataatgaaaaTGTT TACAtttctaggtgtgatcTATTATAATAACAGTCAGAGggactctcgggaggggata a" /listShort="yqgY, S929" /listLong="yqgW, S930" /label="promotor_-10" CDS 2430236..2430481 /gene="yqgY" /locus_tag="BSU_24780" /old_locus_tag="BSU24780" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_390358.1" /db_xref="EnsemblGenomes-Gn:BSU24780" /db_xref="EnsemblGenomes-Tr:CAB14409" /db_xref="GOA:P54502" /db_xref="InterPro:IPR020254" /db_xref="SubtiList:BG11692" /db_xref="UniProtKB/Swiss-Prot:P54502" /translation="MNRMFRVLGFWTGIFAVMFYLGDMKDASLLFFGQTILFVFLSYL NLTERMYIYIFGAYLTIFFAGFTYYSIFIMVPGGGGH*" gene 2430236..2430481 /gene="yqgY" /locus_tag="BSU_24780" /old_locus_tag="BSU24780" downshifts 2430378 /Source="Nicolas_upshifts" /id="D1285" /incds=1 /nref=1 /ntot=86 /MaxReadThrough="6.68961" /MaxDrop="2.1025" /score="22.3415753" /energy="-13.7" /TU="U1924" /idTUdmin="U1923" /TUdmin=176 /isTUend="FALSE" downshifts 2430467 /Source="Nicolas_upshifts" /id="D1286" /incds=0 /nref=98 /ntot=234 /MaxReadThrough="4.03872" /MaxDrop="5.76938" /score="22.3415753" /energy="-13.7" /TU="U1924" /idTUdmin="U1923" /TUdmin=265 /isTUend="FALSE" S_feature 2430512..2431267 /Source="Nicolas_S_feature" /locus_tag="new_2564914_2565669" /HighExp="M9-stat, T0.30H, T1.30H, LoTm, T1.0H, B60, T2.0H, S5, S4, T2.30H" /AntisenseName="yqgX" /AntisenseCor="-0.68109878166952498" /AntisenseRegPval="-37.299999999999997" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="SigEF" /TUlongPSig=1 /label="S929" CDS complement(2430521..2431156) /gene="yqgX" /locus_tag="BSU_24790" /old_locus_tag="BSU24790" /EC_number="3.-.-.-" /function="16.11: Scavenge (Catabolism)" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 20669241, 22333191; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative metal-binding hydrolase" /protein_id="NP_390359.1" /db_xref="EnsemblGenomes-Gn:BSU24790" /db_xref="EnsemblGenomes-Tr:CAB14410" /db_xref="GOA:P54501" /db_xref="InterPro:IPR001279" /db_xref="InterPro:IPR036866" /db_xref="SubtiList:BG11691" /db_xref="UniProtKB/Swiss-Prot:P54501" /translation="MKWRRMPVGPIQANAYFLISDDQCLIFDPGGEGHKINQYIKEKG LTPLAILLTHAHFDHIGALDEVREKWDIPVYLHQNEKNWLADASLNGSGMLRGIEVTA KPADHLIEGDGELNIGPFHLETLFTPGHSPGSVSYYVKDADLVISGDVLFQGGIGRTD LIGGNQETLLTSIHEKLLTLPEHTLVLSGHGPETDVLTEQDQNPFLNGFSL*" gene complement(2430521..2431156) /gene="yqgX" /locus_tag="BSU_24790" /old_locus_tag="BSU24790" downshifts complement(2430546) /Source="Nicolas_upshifts" /id="D1287" /incds=0 /nref=154 /ntot=239 /MaxReadThrough="1.42757" /MaxDrop="5.15622" /score="-8.36666809" /energy="-13.7" /TU="NA" /idTUdmin="U1925" /TUdmin="-4" /isTUend="TRUE" promotor_-10 complement(2431178..2431197) /Source="Nicolas_upshift_promotors" /id="U1925" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.982017982017982" /psig=1 /xcortree=2361 /SigmaFactorBS="ttttttataggtttgtcgatagcgttttcattgcgatTGTTT GAAtcttttttcaaaaACCCTCATAATAAGAGCATAaaaaagaaagaggtgataatag t" /listShort="yqgX" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2431195) /Source="Nicolas_upshifts" /id="U1925" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.982017982017982" /psig=1 /xcortree=2361 /SigmaFactorBS="ttttttataggtttgtcgatagcgttttcattgcgatTGTTT GAAtcttttttcaaaaACCCTCATAATAAGAGCATAaaaaagaaagaggtgataatag t" /listShort="yqgX" /GFF_Attribute="listLong" promotor_-35 complement(2431211..2431218) /Source="Nicolas_upshift_promotors" /id="U1925" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.982017982017982" /psig=1 /xcortree=2361 /SigmaFactorBS="ttttttataggtttgtcgatagcgttttcattgcgatTGTTT GAAtcttttttcaaaaACCCTCATAATAAGAGCATAaaaaagaaagaggtgataatag t" /listShort="yqgX" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 2431235..2431242 /Source="Nicolas_upshift_promotors" /id="U1926" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.703296703296703" /psig=1 /xcortree=514 /SigmaFactorBS="gattcaaacaatcgcaatgaaaacgcTATCGACAaacctata aaaaacAGGTAGAATAAAACTGGAAAgaattgcaggtttttcaatgtaaagggggctg t" /listShort="yqgW, S930" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2431257..2431276 /Source="Nicolas_upshift_promotors" /id="U1926" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.703296703296703" /psig=1 /xcortree=514 /SigmaFactorBS="gattcaaacaatcgcaatgaaaacgcTATCGACAaacctata aaaaacAGGTAGAATAAAACTGGAAAgaattgcaggtttttcaatgtaaagggggctg t" /listShort="yqgW, S930" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2431269 /Source="Nicolas_upshifts" /id="U1926" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.703296703296703" /psig=1 /xcortree=514 /SigmaFactorBS="gattcaaacaatcgcaatgaaaacgcTATCGACAaacctata aaaaacAGGTAGAATAAAACTGGAAAgaattgcaggtttttcaatgtaaagggggctg t" /listShort="yqgW, S930" /GFF_Attribute="listLong" upshifts complement(2431289) /Source="Nicolas_upshifts" /id="U1927" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.996003996003996" /psig=0 /xcortree=709 /SigmaFactorBS="aaagagcgacaaggccgaaaatcacgacaagtAACATaacac agCCCCCTTTACATTGAaaaacctgcaattctttccagttttattctacctgtttttt a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 complement(2431291..2431305) /Source="Nicolas_upshift_promotors" /id="U1927" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.996003996003996" /psig=0 /xcortree=709 /SigmaFactorBS="aaagagcgacaaggccgaaaatcacgacaagtAACATaacac agCCCCCTTTACATTGAaaaacctgcaattctttccagttttattctacctgtttttt a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 complement(2431313..2431317) /Source="Nicolas_upshift_promotors" /id="U1927" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.996003996003996" /psig=0 /xcortree=709 /SigmaFactorBS="aaagagcgacaaggccgaaaatcacgacaagtAACATaacac agCCCCCTTTACATTGAaaaacctgcaattctttccagttttattctacctgtttttt a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" CDS 2431313..2431486 /gene="yqgW" /locus_tag="BSU_24800" /old_locus_tag="BSU24800" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_390360.1" /db_xref="EnsemblGenomes-Gn:BSU24800" /db_xref="EnsemblGenomes-Tr:CAB14411" /db_xref="GOA:P54500" /db_xref="InterPro:IPR024490" /db_xref="SubtiList:BG11690" /db_xref="UniProtKB/Swiss-Prot:P54500" /translation="MLLVVIFGLVALFALWGVLRSVRNKNILGFLLAGATLFVFGWFT VMTVINSGYPTAH*" gene 2431313..2431486 /gene="yqgW" /locus_tag="BSU_24800" /old_locus_tag="BSU24800" downshifts 2431474 /Source="Nicolas_upshifts" /id="D1288" /incds=0 /nref=255 /ntot=278 /MaxReadThrough="3.92092" /MaxDrop="7.18555" /score="14.1643615" /energy="-12.4" /TU="U1926" /idTUdmin="U1924" /TUdmin=217 /isTUend="FALSE" CDS complement(2431518..2431832) /gene="yqgV" /locus_tag="BSU_24810" /old_locus_tag="BSU24810" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_390361.2" /db_xref="EnsemblGenomes-Gn:BSU24810" /db_xref="EnsemblGenomes-Tr:CAB14412" /db_xref="GOA:P54499" /db_xref="InterPro:IPR002767" /db_xref="InterPro:IPR029756" /db_xref="SubtiList:BG11689" /db_xref="UniProtKB/Swiss-Prot:P54499" /translation="MAIADVTIIPIGTETPSVSAYVADVQKILEGYQAEGKIKYQLTP MNTLIEGELSDLFAVIQAIHEAPFQKGLHRVATNIRIDDRRDKKTTLESKIESVNKHL QP*" gene complement(2431518..2431832) /gene="yqgV" /locus_tag="BSU_24810" /old_locus_tag="BSU24810" S_feature 2431519..2432586 /Source="Nicolas_S_feature" /locus_tag="new_2565921_2566988" /HighExp="LoTm, M9-stat, C30, Cold, S8, S7, B60, Lbstat, G135, C90" /AntisenseName="yqgV" /AntisenseCor="-0.23995763414552801" /AntisenseRegPval="-4.2" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="SigA, SigEF" /TUlongPSig="1, 1" /label="S930" downshifts complement(2431532) /Source="Nicolas_upshifts" /id="D1289" /incds=0 /nref=247 /ntot=265 /MaxReadThrough="2.24429" /MaxDrop="6.85096" /score="0.185625845" /energy="-12.4" /TU="NA" /idTUdmin="U1928" /TUdmin="-1" /isTUend="TRUE" CDS complement(2431835..2432896) /gene="yqgU" /locus_tag="BSU_24820" /old_locus_tag="BSU24820" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type lp: lipoprotein" /codon_start=1 /transl_table=11 /product="putative lipoprotein" /protein_id="NP_390362.2" /db_xref="EnsemblGenomes-Gn:BSU24820" /db_xref="EnsemblGenomes-Tr:CAB14413" /db_xref="GOA:P54498" /db_xref="SubtiList:BG11688" /db_xref="UniProtKB/Swiss-Prot:P54498" /translation="MLMRSVCFILLAVLLFSLSACEPSHQQQKQASAAKDEKKDIIPL SAEKADGAEGWLNNSTILYTASNPTKTELFAYRIFTGKAKKLYQTDGQIVDVQINARE QMILLQITHSQKTAVVLLNAEGETLYEKDYETYELEAAWNQYDPYQMMVTEFNENWDF HTYQVNAKKDESFLSPVQVPFIHWTSKNTFDYVKEGRDDKTGPLYTFDTASKTEQKLE DNVLFFDSFHQMSFTVKSASGGKGTYQFKTPQSTSPVTAKWPLQAKYTSLAPMEYDYD EAGGLFYTFKQSGDAYKLAAINVASGETKDLVSLREMEPIQISPNGKYALYGFHFEQI ILLKSHETKQLIIDQKEME*" gene complement(2431835..2432896) /gene="yqgU" /locus_tag="BSU_24820" /old_locus_tag="BSU24820" CDS complement(2432958..2434088) /gene="yqgT" /locus_tag="BSU_24830" /old_locus_tag="BSU24830" /function="16.13: Shape" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 12765833, 24163346; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative d,l-endopeptidase" /protein_id="NP_390363.1" /db_xref="EnsemblGenomes-Gn:BSU24830" /db_xref="EnsemblGenomes-Tr:CAB14414" /db_xref="GOA:P54497" /db_xref="InterPro:IPR000834" /db_xref="InterPro:IPR034274" /db_xref="SubtiList:BG11687" /db_xref="UniProtKB/Swiss-Prot:P54497" /translation="MMAFITVKPEIKNNLANVAKELKIDEELLKSANRSAQKHQLYCP GYVIEEHSGKELQTIQDIKRFLQPRQLKLSDSWIEQEKIYDDSAVEKEIKKIIDVFPF VSCREIGRSVLGRPIWELKAGGEHAVKKVHMNASFHANEWITTSVLLKWFKEYCMSLC CNSPFFGFSPIKLFNSTSLSLVPLVNPDGVDLVLNGSEVMGARRDELERLNEHRPNFN EWKANINGVDLNKQFPSLWEIEKYRKPTAPSYRDFPGISPLTEPESIAMYRLITENPP DRLLALHTQGEEIYWGYKGLEPEESAAVIKEFEELSGNIYKGVRDIDSYAGFRDWFIH HYFKEGYTVELGKGQNPLPFQQFSHIYNATSGILWRALFFHE*" gene complement(2432958..2434088) /gene="yqgT" /locus_tag="BSU_24830" /old_locus_tag="BSU24830" promotor_-10 complement(2434096..2434114) /Source="Nicolas_upshift_promotors" /id="U1928" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.927072927072927" /psig="0.927072927072927" /xcortree=1180 /SigmaFactorBS="cttgatcaggcatcataatcacaatgtctcccgcatcgaagt gagcgggaggcTTTCTTtttttaaatacgctgTCATATAGTAACAAAAAAGggggatg a" /listShort="yqgT, yqgU, yqgV" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2434128) /Source="Nicolas_upshifts" /id="U1928" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.927072927072927" /psig="0.927072927072927" /xcortree=1180 /SigmaFactorBS="cttgatcaggcatcataatcacaatgtctcccgcatcgaagt gagcgggaggcTTTCTTtttttaaatacgctgTCATATAGTAACAAAAAAGggggatg a" /listShort="yqgT, yqgU, yqgV" /GFF_Attribute="listLong" promotor_-35 complement(2434130..2434135) /Source="Nicolas_upshift_promotors" /id="U1928" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.927072927072927" /psig="0.927072927072927" /xcortree=1180 /SigmaFactorBS="cttgatcaggcatcataatcacaatgtctcccgcatcgaagt gagcgggaggcTTTCTTtttttaaatacgctgTCATATAGTAACAAAAAAGggggatg a" /listShort="yqgT, yqgU, yqgV" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2434171..2436087) /gene="ltaSC" /locus_tag="BSU_24840" /old_locus_tag="BSU24840" /function="16.13: Shape" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:15187182, 21255105, 23103977, 25288647, 25666134" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15187182, 21255105, 23103977, 25288647, 25666134; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="enzyme responsible for polyglycerolphosphate LTAsynthesis" /protein_id="NP_390364.2" /db_xref="EnsemblGenomes-Gn:BSU24840" /db_xref="EnsemblGenomes-Tr:CAB14415" /db_xref="GOA:P54496" /db_xref="InterPro:IPR000917" /db_xref="InterPro:IPR012160" /db_xref="InterPro:IPR017849" /db_xref="InterPro:IPR017850" /db_xref="SubtiList:BG11686" /db_xref="UniProtKB/Swiss-Prot:P54496" /translation="MRKTFFSKISFMLIAILLMWLKTYAVYKTSFHIKIDNLTQEFIL FINPLSFLLLIFGLSLFLKGKNRNRYIIAMSCLVTFVLLANMVFYRFYNDFLTIPVLF QTSNMGDLGSSIGTLLEPTDLLLAVDIAVLIWLHIRQKAFQSDIPSTKNERAAYFLFV ASVYFFNLGLSEAERPQLLTRSFDREMLVKNISLFNFHIYDGVLQSKQSAQRALADSN SLTEIENYVTANAKDANKRLFGAAKGRNVILVSLESTQSFVINEKLNGEEITPFLNDF IKQSYNFNNVYHQTGQGKTSDSEFIVDNSLYPLGRGAVFFTNAGNQYMAAPEILKNSG YYSAVLHANNKSFWNRDLMYDSFGYDSFFDINSYDVTDENSVGWGLKDKEFFEQSSEL MKNLPQPFYSRLITLTNHFPFDLDEEDQLIDEYDSNSQTLNKYFPTVRYQDEALKRFI EKLKEDGLYDNSVIVLYGDHYGISENHNEAMGQFLGKEITPFEEVQLQKVPLVIHIPG ITDKKPQTIETVGGQIDIRPTLMNLLGIDTKDQIQFGNDLLSDEKLDFTVLRDGSFIT DQVVYTDGACYDKETGKPLEETKQCEAFADKAKQELSLSDEIIYGDLLRFYDQKRLDN SSKRKEKQMLDQAS*" gene complement(2434171..2436087) /gene="ltaSC" /locus_tag="BSU_24840" /old_locus_tag="BSU24840" downshifts complement(2434198) /Source="Nicolas_upshifts" /id="D1290" /incds=0 /nref=5 /ntot=142 /MaxReadThrough="4.5611" /MaxDrop="3.8416" /score="15.4764643" /energy="-14.5" /TU="U1930,U1931" /idTUdmin="U1928" /TUdmin="-2667" /isTUend="FALSE" promotor_-35 2435203..2435209 /Source="Nicolas_upshift_promotors" /id="U1929" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=213 /SigmaFactorBS="agcggatacagtgaattgtccacgataaattcagaatccgaG GTTTTCccctggcctgtttggTGGTAAACATTATTAAAGTtgtagctctgttttataa a" /listShort="S931" /GFF_Attribute="listLong" /label="promotor_-35" S_feature 2435222..2436251 /Source="Nicolas_S_feature" /locus_tag="new_2569624_2570653" /HighExp="Etha, Gly, M9-stat, Salt, S8, LPhT, S7, Sw, HiTm, B60" /AntisenseName="yqgS" /AntisenseCor="-0.36996929809172002" /AntisenseRegPval="-9.4" /CDS_PredictionProba="NA" /TUshortSig="SigB" /TUshortPSig="0.998" /TUlongSig="NA" /TUlongPSig="NA" /label="S931" upshifts 2435222 /Source="Nicolas_upshifts" /id="U1929" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=213 /SigmaFactorBS="agcggatacagtgaattgtccacgataaattcagaatccgaG GTTTTCccctggcctgtttggTGGTAAACATTATTAAAGTtgtagctctgttttataa a" /listShort="S931" /GFF_Attribute="listLong" promotor_-10 2435225..2435243 /Source="Nicolas_upshift_promotors" /id="U1929" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=213 /SigmaFactorBS="agcggatacagtgaattgtccacgataaattcagaatccgaG GTTTTCccctggcctgtttggTGGTAAACATTATTAAAGTtgtagctctgttttataa a" /listShort="S931" /GFF_Attribute="listLong" /label="promotor_-10" S_feature complement(2436088..2436154) /Source="Nicolas_S_feature" /locus_tag="new_2570490_2570556_c" /HighExp="T-3.40H, BC, Sw, S5, Lbstat, T-5.40H, S4, ferm, C30, nit" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="1, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S932" promotor_-10 complement(2436148..2436167) /Source="Nicolas_upshift_promotors" /id="U1930" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.483516483516484" /psig=1 /xcortree=3130 /SigmaFactorBS="aaaattgttaaaattgtgtaaatgaAATTGATTttttgttgt gctcaGGTTAAGATTTAATTTGATGtgttaatgagaatgttgggaatagactgatttt t" /listShort="S932, yqgS, yqgT, yqgU, yqgV" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2436154) /Source="Nicolas_upshifts" /id="U1930" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.483516483516484" /psig=1 /xcortree=3130 /SigmaFactorBS="aaaattgttaaaattgtgtaaatgaAATTGATTttttgttgt gctcaGGTTAAGATTTAATTTGATGtgttaatgagaatgttgggaatagactgatttt t" /listShort="S932, yqgS, yqgT, yqgU, yqgV" /GFF_Attribute="listLong" promotor_-35 complement(2436182..2436189) /Source="Nicolas_upshift_promotors" /id="U1930" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.483516483516484" /psig=1 /xcortree=3130 /SigmaFactorBS="aaaattgttaaaattgtgtaaatgaAATTGATTttttgttgt gctcaGGTTAAGATTTAATTTGATGtgttaatgagaatgttgggaatagactgatttt t" /listShort="S932, yqgS, yqgT, yqgU, yqgV" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2436204..2437169) /gene="glcK" /locus_tag="BSU_24850" /old_locus_tag="BSU24850" /EC_number="2.7.1.59" /EC_number="2.7.1.2" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:9620975, 10737197, 15018644, 15050034, 20495944, 21108133, 27324299" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9620975, 10737197, 15018644, 15050034, 20495944, 21108133, 27324299; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="glucose kinase" /protein_id="NP_390365.2" /db_xref="EnsemblGenomes-Gn:BSU24850" /db_xref="EnsemblGenomes-Tr:CAB14416" /db_xref="GOA:P54495" /db_xref="InterPro:IPR000600" /db_xref="InterPro:IPR004654" /db_xref="SubtiList:BG11685" /db_xref="UniProtKB/Swiss-Prot:P54495" /translation="MDEIWFAGIDLGGTTIKLAFINQYGEIQHKWEVPTDKTGDTITV TIAKTIDSKLDELQKPKHIIKYIGMGAPGPVDMAAGVVYETVNLGWKNYALKNHLETE TGIPAVIENDANIAALGEMWKGAGDGAKDVILVTLGTGVGGGIIANGEIVHGINGAGG EIGHICSIPEGGAPCNCGKTGCIETIASATGIVRIAKEKIANAKKTTRLKATEQLSAR DVFEAAGENDEIALEVVDYVAKHLGLVLGNLASSLNPSKIVLGGGVSRAGELLRSKVE KTFRKCAFPRAAQAADISIAALGNDAGVIGGAWIAKNEWLKHQNC*" gene complement(2436204..2437169) /gene="glcK" /locus_tag="BSU_24850" /old_locus_tag="BSU24850" CDS complement(2437180..2437395) /gene="yqgQ" /locus_tag="BSU_24860" /old_locus_tag="BSU24860" /function="9.3: Transcription factors" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15050034, 20057058; Product type f: factor" /codon_start=1 /transl_table=11 /product="putative single strand nucleic acid binding transcription factor" /protein_id="NP_390366.1" /db_xref="EnsemblGenomes-Gn:BSU24860" /db_xref="EnsemblGenomes-Tr:CAB14417" /db_xref="InterPro:IPR009256" /db_xref="InterPro:IPR023164" /db_xref="PDB:2NN4" /db_xref="SubtiList:BG11684" /db_xref="UniProtKB/Swiss-Prot:P54494" /translation="MNTFYDVQQLLKTFGHIVYFGDRELEIEFMLDELKELYMNHMIE KEQWARAAAVLRKELEQTKNGRDFYKG*" gene complement(2437180..2437395) /gene="yqgQ" /locus_tag="BSU_24860" /old_locus_tag="BSU24860" S_feature complement(2437396..2437504) /Source="Nicolas_S_feature" /locus_tag="new_2571798_2571906_c" /HighExp="M0t90, Lbstat, M40t90, M40t45, Lbtran, Mt0, dia5, Diami, M0t45, BI" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S933" CDS complement(2437505..2439028) /gene="glpG" /locus_tag="BSU_24870" /old_locus_tag="BSU24870" /EC_number="3.4.21.105" /function="16.1: Circulate" /function="16.13: Shape" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 15050034, 16355228, 23518036, 26858402; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="membrane endopeptidase" /protein_id="NP_390367.2" /db_xref="EnsemblGenomes-Gn:BSU24870" /db_xref="EnsemblGenomes-Tr:CAB14418" /db_xref="GOA:P54493" /db_xref="InterPro:IPR011990" /db_xref="InterPro:IPR013026" /db_xref="InterPro:IPR019734" /db_xref="InterPro:IPR022764" /db_xref="InterPro:IPR035952" /db_xref="SubtiList:BG11683" /db_xref="UniProtKB/Swiss-Prot:P54493" /translation="MFLLEYTYWKIAAHLVNSGYGVIQAGESDEIWLEAPDKSSHDLV RLYKHDLDFRQEMVRDIEEQAERVERVRHQLGRRRMKLLNVFFSTEAPVDDWEEIAKK TFEKGTVSVEPAIVRGTMLRDDLQAVFPSFRTEDCSEEHASFENAQMARERFLSLVLK QEEQRKTEAAVFQNGKPTFTYLFIALQILMFFLLEINGGSTNTETLVAFGAKENSLIA QGEWWRLLTPIVLHIGIAHLAFNTLALWSVGTAVERMYGSGRFLLIYLAAGITGSIAS FVFSPYPSAGASGAIFGCLGALLYVALSNRKMFLRTIGTNIIVIIIINLGFGFAVSNI DNSGHIGGLIGGFFAAAALGLPKAGAFGKRLLSAVLLIALAVGFLYYGLHSPSHQESA LIQQASELYQEGKYEEVTELLNGEAAQKDASADLLKILAVSDIQIGEYDQAVSLLERA VKKEPKDHASYYNLALLYAEKNELAQAEKAIQTAVKLKPKEQRYKELQRQIENNKES* " gene complement(2437505..2439028) /gene="glpG" /locus_tag="BSU_24870" /old_locus_tag="BSU24870" promotor_-10 complement(2439046..2439065) /Source="Nicolas_upshift_promotors" /id="U1931" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.602397602397602" /psig=1 /xcortree=2337 /SigmaFactorBS="aaaatcccgtgaaaaacgggattttttgctttCAGTAGGCgt ttcggagcgccaGCTGTTATAATGAAAAAAAActattggagcggtaaacatgtttttg c" /listShort="glpG, S933, yqgQ, glcK, S932, yqgS, yqgT, yqgU, yqgV" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2439059) /Source="Nicolas_upshifts" /id="U1931" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.602397602397602" /psig=1 /xcortree=2337 /SigmaFactorBS="aaaatcccgtgaaaaacgggattttttgctttCAGTAGGCgt ttcggagcgccaGCTGTTATAATGAAAAAAAActattggagcggtaaacatgtttttg c" /listShort="glpG, S933, yqgQ, glcK, S932, yqgS, yqgT, yqgU, yqgV" /GFF_Attribute="listLong" promotor_-35 complement(2439080..2439087) /Source="Nicolas_upshift_promotors" /id="U1931" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.602397602397602" /psig=1 /xcortree=2337 /SigmaFactorBS="aaaatcccgtgaaaaacgggattttttgctttCAGTAGGCgt ttcggagcgccaGCTGTTATAATGAAAAAAAActattggagcggtaaacatgtttttg c" /listShort="glpG, S933, yqgQ, glcK, S932, yqgS, yqgT, yqgU, yqgV" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2439118..2439291) /gene="yqgO" /locus_tag="BSU_24880" /old_locus_tag="BSU24880" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_390368.1" /db_xref="EnsemblGenomes-Gn:BSU24880" /db_xref="EnsemblGenomes-Tr:CAB14419" /db_xref="SubtiList:BG11682" /db_xref="UniProtKB/Swiss-Prot:P54492" /translation="MKKLLIYAIFAVSAVMFYQNRYRLMNTVLSQPGIRRSFIHLFLR IPFIRNKFIQQAF*" gene complement(2439118..2439291) /gene="yqgO" /locus_tag="BSU_24880" /old_locus_tag="BSU24880" downshifts complement(2439145) /Source="Nicolas_upshifts" /id="D1291" /incds=0 /nref=121 /ntot=211 /MaxReadThrough="2.93694" /MaxDrop="5.6047" /score="19.2452946" /energy="-8.9" /TU="NA" /idTUdmin="U1932" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(2439307..2439318) /Source="Nicolas_upshift_promotors" /id="U1932" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.99000999000999" /psig="0.99000999000999" /xcortree=909 /SigmaFactorBS="gattatttcttgtttttcataactttcctgtcccttattcgA GAATAAataaggtagaataACAAACCCTATTggcaggagggatatcatgaaaaaactt t" /listShort="yqgO" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2439319) /Source="Nicolas_upshifts" /id="U1932" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.99000999000999" /psig="0.99000999000999" /xcortree=909 /SigmaFactorBS="gattatttcttgtttttcataactttcctgtcccttattcgA GAATAAataaggtagaataACAAACCCTATTggcaggagggatatcatgaaaaaactt t" /listShort="yqgO" /GFF_Attribute="listLong" promotor_-35 complement(2439332..2439338) /Source="Nicolas_upshift_promotors" /id="U1932" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.99000999000999" /psig="0.99000999000999" /xcortree=909 /SigmaFactorBS="gattatttcttgtttttcataactttcctgtcccttattcgA GAATAAataaggtagaataACAAACCCTATTggcaggagggatatcatgaaaaaactt t" /listShort="yqgO" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2439358..2439921) /gene="folN" /locus_tag="BSU_24890" /old_locus_tag="BSU24890" /EC_number="6.3.3.2" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 17329806, 20952389, 22773193; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="5-formyltetrahydrofolate cyclo-ligase" /protein_id="NP_390369.1" /db_xref="EnsemblGenomes-Gn:BSU24890" /db_xref="EnsemblGenomes-Tr:CAB14420" /db_xref="GOA:P54491" /db_xref="InterPro:IPR002698" /db_xref="PDB:1YDM" /db_xref="SubtiList:BG11681" /db_xref="UniProtKB/Swiss-Prot:P54491" /translation="MKSQLRKKTLEALSALSNEDILQKTERMYKYLFSLPEWQNAGTI AVTISRGLEIPTRPVIEQAWEEGKQVCIPKCHPDTKKMQFRTYQTDDQLETVYAGLLE PVIEKTKEVNPSQIDLMIVPGVCFDVNGFRVGFGGGYYDRYLSEYEGKTVSLLLECQL FAHVPRLPHDIPVHKLITEDRIISCFS*" gene complement(2439358..2439921) /gene="folN" /locus_tag="BSU_24890" /old_locus_tag="BSU24890" S_feature complement(2439922..2440005) /Source="Nicolas_S_feature" /locus_tag="new_2574324_2574407_c" /HighExp="Cold, G180, LBGexp, LBGtran, G135, HPh, LPh, dia0, Oxctl, Lbexp" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S934" CDS complement(2440006..2440155) /gene="rpmGA" /locus_tag="BSU_24900" /old_locus_tag="BSU24900" /function="16.2: Construct biomass (Anabolism)" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 12682299, 12904577, 19648245, 22720735, 23002217, 27561249; Product type s : structure" /codon_start=1 /transl_table=11 /product="ribosomal protein L33" /protein_id="NP_570908.2" /db_xref="EnsemblGenomes-Gn:BSU24900" /db_xref="EnsemblGenomes-Tr:CAE01461" /db_xref="GOA:P56849" /db_xref="InterPro:IPR001705" /db_xref="InterPro:IPR011332" /db_xref="InterPro:IPR018264" /db_xref="PDB:3J9W" /db_xref="PDB:5NJT" /db_xref="SubtiList:BG14180" /db_xref="UniProtKB/Swiss-Prot:P56849" /translation="MRVNITLACTECGERNYISKKNKRNNPDRVEFKKYCPRDKKSTL HRETK*" gene complement(2440006..2440155) /gene="rpmGA" /locus_tag="BSU_24900" /old_locus_tag="BSU24900" downshifts complement(2440052) /Source="Nicolas_upshifts" /id="D1292" /incds=0 /nref=154 /ntot=253 /MaxReadThrough="5.3064" /MaxDrop="4.5881" /score="34.7393253" /energy="-15.3" /TU="U1933" /idTUdmin="U1932" /TUdmin="-907" /isTUend="FALSE" promotor_-10 complement(2440192..2440211) /Source="Nicolas_upshift_promotors" /id="U1933" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.778221778221778" /psig=1 /xcortree=2638 /SigmaFactorBS="ttcaataattcagcaattcattgaaaaacagcCTAGcattcc gtccattatAGTGGTATTATATATAAGTCtgaataagtaaatgattttagtttggagg g" /listShort="rpmGA, S934, yqgN, yqgO" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2440202) /Source="Nicolas_upshifts" /id="U1933" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.778221778221778" /psig=1 /xcortree=2638 /SigmaFactorBS="ttcaataattcagcaattcattgaaaaacagcCTAGcattcc gtccattatAGTGGTATTATATATAAGTCtgaataagtaaatgattttagtttggagg g" /listShort="rpmGA, S934, yqgN, yqgO" /GFF_Attribute="listLong" promotor_-35 complement(2440227..2440230) /Source="Nicolas_upshift_promotors" /id="U1933" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.778221778221778" /psig=1 /xcortree=2638 /SigmaFactorBS="ttcaataattcagcaattcattgaaaaacagcCTAGcattcc gtccattatAGTGGTATTATATATAAGTCtgaataagtaaatgattttagtttggagg g" /listShort="rpmGA, S934, yqgN, yqgO" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2440239..2441318) /gene="yqgM" /locus_tag="BSU_24910" /old_locus_tag="BSU24910" /EC_number="2.4.1.-" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative glycosyltransferase" /protein_id="NP_390370.2" /db_xref="EnsemblGenomes-Gn:BSU24910" /db_xref="EnsemblGenomes-Tr:CAB14421" /db_xref="GOA:P54490" /db_xref="InterPro:IPR001296" /db_xref="InterPro:IPR028098" /db_xref="SubtiList:BG11680" /db_xref="UniProtKB/Swiss-Prot:P54490" /translation="MNILMLSPEHPDEPKSGLGVHLNRLISYLNPHINITVFTPSGQL FSYAKFEDYIADANFTMVRHVLSHNKRFDLIHAHDDTTAPAAQYLKQRLGLPLAATIH GLESERKKVCREAPHPYRLMTERLLIESADALIVLSTFMKRSLDKAAHKKITVIPSPA SMEEEKGKIPRSMNRRFLFSYGRFVPEKGLSQLLKVFAILKQRQPDLYLVLAGEGPSL SCYEKLAAAYNLKDRVMFLPFLNRKDIRTLLSHCEMAVFPSSYEPFGLAAQESMEQGV LTVVSQSGGFCDYAVHDKTAIIADFTLVQEAADLLDSFLKDREKARRIKEAGRQQVFK LHHPRLIMSSYLQLYERIFNNSAIH*" gene complement(2440239..2441318) /gene="yqgM" /locus_tag="BSU_24910" /old_locus_tag="BSU24910" CDS complement(2441315..2441785) /gene="yqgL" /locus_tag="BSU_24920" /old_locus_tag="BSU24920" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_390371.1" /db_xref="EnsemblGenomes-Gn:BSU24920" /db_xref="EnsemblGenomes-Tr:CAB14422" /db_xref="SubtiList:BG11679" /db_xref="UniProtKB/Swiss-Prot:P54489" /translation="MDKHPFPYNIRHKLSFFRDTFDIIIQNAHTLTVSWEISEETMRL AEAVLFEKTQDMIKELRIVIKRKDIEAVRTKRTTYDKGEWTIRQAAGDAVYRAEYRIV NSMNVSLKLAGTDDIYLDENGIRHINSFQIEEAHTRWEAQFSAYTCYGRGEKER*" gene complement(2441315..2441785) /gene="yqgL" /locus_tag="BSU_24920" /old_locus_tag="BSU24920" promotor_-35 2441730..2441738 /Source="Nicolas_upshift_promotors" /id="U1934" /multdbtbs="-" /comp="M2" /sig="SigI" /pcomp="0.982017982017982" /psig="0.982017982017982" /xcortree=1724 /SigmaFactorBS="aaggtgtgagcgttttgaatgattatgtcgaatgtgTCCCTA AAAaaggaaagcttatGTCGTATATtatagggaaatgggtgtttatccatggactcct a" /listShort="S935, yqzD, yqzC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2441752..2441760 /Source="Nicolas_upshift_promotors" /id="U1934" /multdbtbs="-" /comp="M2" /sig="SigI" /pcomp="0.982017982017982" /psig="0.982017982017982" /xcortree=1724 /SigmaFactorBS="aaggtgtgagcgttttgaatgattatgtcgaatgtgTCCCTA AAAaaggaaagcttatGTCGTATATtatagggaaatgggtgtttatccatggactcct a" /listShort="S935, yqzD, yqzC" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 2441753..2441926 /Source="Nicolas_S_feature" /locus_tag="new_2576155_2576328" /HighExp="M9-stat, T1.0H, T1.30H, T0.30H, T2.0H, T2.30H, T3.0H, Lbstat, T3.30H, B60" /AntisenseName="yqgL" /AntisenseCor="0.210779859401483" /AntisenseRegPval="-3.3" /CDS_PredictionProba="NA" /TUshortSig="SigI" /TUshortPSig="0.982" /TUlongSig="NA" /TUlongPSig="NA" /label="S935" upshifts 2441754 /Source="Nicolas_upshifts" /id="U1934" /multdbtbs="-" /comp="M2" /sig="SigI" /pcomp="0.982017982017982" /psig="0.982017982017982" /xcortree=1724 /SigmaFactorBS="aaggtgtgagcgttttgaatgattatgtcgaatgtgTCCCTA AAAaaggaaagcttatGTCGTATATtatagggaaatgggtgtttatccatggactcct a" /listShort="S935, yqzD, yqzC" /GFF_Attribute="listLong" promotor_-10 complement(2441821..2441840) /Source="Nicolas_upshift_promotors" /id="U1935" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.768231768231768" /psig="0.999000999001" /xcortree=2933 /SigmaFactorBS="cgcgaaaaaaacgagattttgtcgagaaatctttCTTCGCTT cttcttcatgtAATGGTTTAATAGGAACACGaagtgaacgattggaaaggagaatgtt a" /listShort="yqgL" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2441833) /Source="Nicolas_upshifts" /id="U1935" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.768231768231768" /psig="0.999000999001" /xcortree=2933 /SigmaFactorBS="cgcgaaaaaaacgagattttgtcgagaaatctttCTTCGCTT cttcttcatgtAATGGTTTAATAGGAACACGaagtgaacgattggaaaggagaatgtt a" /listShort="yqgL" /GFF_Attribute="listLong" promotor_-35 complement(2441852..2441859) /Source="Nicolas_upshift_promotors" /id="U1935" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.768231768231768" /psig="0.999000999001" /xcortree=2933 /SigmaFactorBS="cgcgaaaaaaacgagattttgtcgagaaatctttCTTCGCTT cttcttcatgtAATGGTTTAATAGGAACACGaagtgaacgattggaaaggagaatgtt a" /listShort="yqgL" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 2441898..2441902 /Source="Nicolas_upshift_promotors" /id="U1936" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.806193806193806" /psig="0.995004995004995" /xcortree=2671 /SigmaFactorBS="ctcgacaaaatctcgtttttttcgcgaattCCTTTagaaact attggtttTATGGTATAAAAAAGAAGGAtaaaaaaagaatagaaggtgatgaaacgtg g" /listShort="yqzD, yqzC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2441918..2441937 /Source="Nicolas_upshift_promotors" /id="U1936" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.806193806193806" /psig="0.995004995004995" /xcortree=2671 /SigmaFactorBS="ctcgacaaaatctcgtttttttcgcgaattCCTTTagaaact attggtttTATGGTATAAAAAAGAAGGAtaaaaaaagaatagaaggtgatgaaacgtg g" /listShort="yqzD, yqzC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2441928 /Source="Nicolas_upshifts" /id="U1936" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.806193806193806" /psig="0.995004995004995" /xcortree=2671 /SigmaFactorBS="ctcgacaaaatctcgtttttttcgcgaattCCTTTagaaact attggtttTATGGTATAAAAAAGAAGGAtaaaaaaagaatagaaggtgatgaaacgtg g" /listShort="yqzD, yqzC" /GFF_Attribute="listLong" CDS 2441965..2442318 /gene="yqzD" /locus_tag="BSU_24930" /old_locus_tag="BSU24930" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_390372.1" /db_xref="EnsemblGenomes-Gn:BSU24930" /db_xref="EnsemblGenomes-Tr:CAB14423" /db_xref="GOA:O32022" /db_xref="SubtiList:BG13770" /db_xref="UniProtKB/Swiss-Prot:O32022" /translation="MEIAIIALFIVSIALIAFSYSQRDPMKDVEQELETLQLSAMQEI YKLKKKMTVLEEELLETNLVIRKSKQNDINQKIAKQILSKYNNGMSAEAIAKAEHVSV EDVNTIIKDNEKVLV*" gene 2441965..2442318 /gene="yqzD" /locus_tag="BSU_24930" /old_locus_tag="BSU24930" CDS 2442315..2442779 /gene="yqzC" /locus_tag="BSU_24940" /old_locus_tag="BSU24940" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 22720735" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_390373.2" /db_xref="EnsemblGenomes-Gn:BSU24940" /db_xref="EnsemblGenomes-Tr:CAB14424" /db_xref="InterPro:IPR003770" /db_xref="SubtiList:BG13769" /db_xref="UniProtKB/Swiss-Prot:O32023" /translation="MTKRGIQAFAGGIILATAVLAAVFYLTDEDQAAAVKDNKTVTEQ DVNNYLDSKKLVSVNRDEYQKLLDSKEKSLNNDSGSDTKSDKVKTYKLTIKDGMSTAD VSAILEKEGIISSAQDFNDYVIDAGYHKEIRAGEFKVKSDMSFKKIVKTLTR*" gene 2442315..2442779 /gene="yqzC" /locus_tag="BSU_24940" /old_locus_tag="BSU24940" downshifts 2442765 /Source="Nicolas_upshifts" /id="D1293" /incds=0 /nref=216 /ntot=264 /MaxReadThrough="0.9847" /MaxDrop="6.07831" /score="21.2108939" /energy="-8.8" /TU="NA" /idTUdmin="U1934" /TUdmin=0 /isTUend="TRUE" CDS complement(2442808..2443590) /gene="pstBB" /locus_tag="BSU_24950" /old_locus_tag="BSU24950" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:8760913, 9098050, 12897025, 15289558" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8760913, 9098050, 12897025, 15289558; Product type t: transporter" /codon_start=1 /transl_table=11 /product="phosphate ABC transporter (ATP-binding protein)" /protein_id="NP_390374.1" /db_xref="EnsemblGenomes-Gn:BSU24950" /db_xref="EnsemblGenomes-Tr:CAB14425" /db_xref="GOA:P46342" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR005670" /db_xref="InterPro:IPR015850" /db_xref="InterPro:IPR017871" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG11379" /db_xref="UniProtKB/Swiss-Prot:P46342" /translation="MSIATEAVMKQEVYQVNGMNLWYGQHHALKNINLSIYENEVTAI IGPSGCGKSTFIKTLNLMIQMTPNVKLAGELNYNGSNILKDKVDIVDLRKNIGMVFQK GNPFPQSIFDNVAYGPRVHGTKNKKKLQEIVEKSLKDVALWDEVKDRLHTSALSLSGG QQQRLCIARALATNPDILLMDEPTSALDPISTRKIEELILELKDKYTIVIVTHNMQQA ARVSDQTAFFYMGELVECDNTNKMFSNPKDQRTLDYISGKFG*" gene complement(2442808..2443590) /gene="pstBB" /locus_tag="BSU_24950" /old_locus_tag="BSU24950" downshifts complement(2442819) /Source="Nicolas_upshifts" /id="D1294" /incds=0 /nref=20 /ntot=46 /MaxReadThrough="2.29658" /MaxDrop="6.53816" /score="26.1659198" /energy="-8.8" /TU="NA" /idTUdmin="U1937" /TUdmin=0 /isTUend="TRUE" CDS complement(2443601..2444410) /gene="pstBA" /locus_tag="BSU_24960" /old_locus_tag="BSU24960" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:8760913, 9098050, 12897025, 15289558" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8760913, 9098050, 12897025, 15289558; Product type t: transporter" /codon_start=1 /transl_table=11 /product="phosphate ABC transporter (ATP-binding protein)" /protein_id="NP_390375.1" /db_xref="EnsemblGenomes-Gn:BSU24960" /db_xref="EnsemblGenomes-Tr:CAB14426" /db_xref="GOA:P46341" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR005670" /db_xref="InterPro:IPR015850" /db_xref="InterPro:IPR017871" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG11378" /db_xref="UniProtKB/Swiss-Prot:P46341" /translation="MSEQMVKEKPERAVIVPKQNHVLEVKDLSIYYGNKQAVHHVNMD IEKNAVTALIGPSGCGKSTFLRNINRMNDLIPSARAEGEILYEGLNILGGNINVVSLR REIGMVFQKPNPFPKSIYANITHALKYAGERNKAVLDEIVEESLTKAALWDEVKDRLH SSALSLSGGQQQRLCIARTLAMKPAVLLLDEPASALDPISNAKIEELITGLKREYSII IVTHNMQQALRVSDRTAFFLNGELVEYGQTEQIFTSPKKQKTEDYINGKFG*" gene complement(2443601..2444410) /gene="pstBA" /locus_tag="BSU_24960" /old_locus_tag="BSU24960" CDS complement(2444431..2445315) /gene="pstA" /locus_tag="BSU_24970" /old_locus_tag="BSU24970" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:9098050, 12897025, 15289558, 15849754, 16850406" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9098050, 12897025, 15289558, 15849754, 16850406; Product type t : transporter" /codon_start=1 /transl_table=11 /product="phosphate ABC transporter (permease)" /protein_id="NP_390376.2" /db_xref="EnsemblGenomes-Gn:BSU24970" /db_xref="EnsemblGenomes-Tr:CAB14427" /db_xref="GOA:P46340" /db_xref="InterPro:IPR000515" /db_xref="InterPro:IPR005672" /db_xref="InterPro:IPR035906" /db_xref="SubtiList:BG11377" /db_xref="UniProtKB/Swiss-Prot:P46340" /translation="MNRKITDKLATGMFGLCAAIIAAILVGLFSYIIINGVSQLSFQF ITTKSSAIAAGGGIRDQLFNSFYILFITMLITIPLGVGGGVFMAEYAPNNKVTDFIRT CIEVLSSLPSIVIGMFGLLMFVNLTGWGYTIIGGALALTVFNLPVMVRVTEDAIRSVP KDLKEASLALGVSRWHTVKTVLIPSAIPSIITGAILASGRVFGEAAALLFTAGLTTPR LNFTEWNPFSETSPLNIFRPAETLAVHIWNVNTQGMIPDAEAIANGGSAVLVISVLVF NLAARWLGTMIYKKLTAN*" gene complement(2444431..2445315) /gene="pstA" /locus_tag="BSU_24970" /old_locus_tag="BSU24970" CDS complement(2445315..2446244) /gene="pstC" /locus_tag="BSU_24980" /old_locus_tag="BSU24980" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:9098050, 12897025, 15289558, 15849754, 16850406" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9098050, 12897025, 15289558, 15849754, 16850406; Product type t : transporter" /codon_start=1 /transl_table=11 /product="phosphate ABC transporter (permease)" /protein_id="NP_390377.2" /db_xref="EnsemblGenomes-Gn:BSU24980" /db_xref="EnsemblGenomes-Tr:CAB14428" /db_xref="GOA:P46339" /db_xref="InterPro:IPR000515" /db_xref="InterPro:IPR011864" /db_xref="InterPro:IPR035906" /db_xref="SubtiList:BG11376" /db_xref="UniProtKB/Swiss-Prot:P46339" /translation="MINNRENMSVSERLISSRQNRQLDEVRGRMIVTACALIMIAASV AITIFLGVKGLQSFLVNGVSPIEFLTSLNWNPTDSDPKYGVLPFIFGSFAVTILSALI AAPLGIAGAIFMTEIAPNWGKKVLQPVIELLVGIPSVVYGFIGLTVLVPFIAQFKSSG TGHSLLAGTIVLSVMILPTITSISADAMASLPKSLREGSYALGATRWQTIRKVLVPAA FPTLMTAVVLGMARAFGEALAVQMVIGNTRVLPESPFDTAGTLTTIITLNMGHTTYGS VENNTLWSMGLVLLVMSFLFILLIRYLSSRRKV*" gene complement(2445315..2446244) /gene="pstC" /locus_tag="BSU_24980" /old_locus_tag="BSU24980" CDS complement(2446313..2447215) /gene="pstS" /locus_tag="BSU_24990" /old_locus_tag="BSU24990" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:9098050, 9593301, 10913081, 15289558, 21461370, 25355936" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9098050, 9593301, 10913081, 15289558, 21461370, 25355936; Product type t : transporter" /codon_start=1 /transl_table=11 /product="phosphate ABC transporter (phosphate binding lipoprotein)" /protein_id="NP_390378.1" /db_xref="EnsemblGenomes-Gn:BSU24990" /db_xref="EnsemblGenomes-Tr:CAB14429" /db_xref="GOA:P46338" /db_xref="InterPro:IPR011862" /db_xref="InterPro:IPR024370" /db_xref="SubtiList:BG11375" /db_xref="UniProtKB/Swiss-Prot:P46338" /translation="MKKNKLVLMLLMAAFMMIAAACGNAGESKKSNSDSAKGEEKASG SLTISGSSAMQPLVLAAAEKFMEENPDADIQVQAGGSGTGLSQVSEGAVQIGNSDVFA EEKEGIDAKALVDHQVAVVGMAAAVNPDAGVKDISKDELKKIFTGKIKNWKELGGKDQ KITLVNRPDSSGTRATFVKYALDGAEPAEGITEDSSNTVKKIIADTPGAIGYLAFSYL TDDKVTALSIDGVKPEAKNVATGEYPIWAYQHSYTKGEATGLAKEFLDYLKSEDIQKS IVTDQGYIPVTDMKVTRDANGKQS*" gene complement(2446313..2447215) /gene="pstS" /locus_tag="BSU_24990" /old_locus_tag="BSU24990" upshifts complement(2447270) /Source="Nicolas_upshifts" /id="U1937" /multdbtbs="SigA" /comp="M6" /sig="Sig-" /pcomp="0.977022977022977" /psig="0.014985014985015" /xcortree=7 /SigmaFactorBS="aaaaaacgcactgatttacaaaaCCTtaacattcggTTCAAA CCCTTTTTACAtagaacctttactctatacgtgtaggacaaattacacattatacgca g" /listShort="pstS, pstC, pstA, pstBA, pstBB" /GFF_Attribute="listLong" promotor_-10 complement(2447278..2447294) /Source="Nicolas_upshift_promotors" /id="U1937" /multdbtbs="SigA" /comp="M6" /sig="Sig-" /pcomp="0.977022977022977" /psig="0.014985014985015" /xcortree=7 /SigmaFactorBS="aaaaaacgcactgatttacaaaaCCTtaacattcggTTCAAA CCCTTTTTACAtagaacctttactctatacgtgtaggacaaattacacattatacgca g" /listShort="pstS, pstC, pstA, pstBA, pstBB" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 complement(2447305..2447307) /Source="Nicolas_upshift_promotors" /id="U1937" /multdbtbs="SigA" /comp="M6" /sig="Sig-" /pcomp="0.977022977022977" /psig="0.014985014985015" /xcortree=7 /SigmaFactorBS="aaaaaacgcactgatttacaaaaCCTtaacattcggTTCAAA CCCTTTTTACAtagaacctttactctatacgtgtaggacaaattacacattatacgca g" /listShort="pstS, pstC, pstA, pstBA, pstBB" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2447369..2449519) /gene="pbpA" /locus_tag="BSU_25000" /old_locus_tag="BSU25000" /EC_number="3.4.-.-" /function="16.2: Construct biomass (Anabolism)" /function="16.13: Shape" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:9139922, 9851991, 12896990, 17307860" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9139922, 9851991, 12896990, 17307860; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="transpeptidase (penicillin-binding protein 2A)" /protein_id="NP_390379.1" /db_xref="EnsemblGenomes-Gn:BSU25000" /db_xref="EnsemblGenomes-Tr:CAB14430" /db_xref="GOA:P54488" /db_xref="InterPro:IPR001460" /db_xref="InterPro:IPR005311" /db_xref="InterPro:IPR012338" /db_xref="InterPro:IPR036138" /db_xref="SubtiList:BG11678" /db_xref="UniProtKB/Swiss-Prot:P54488" /translation="MRRNKPKKQNHKEKKKSLPIRLNILFLAAFVIFTWIIVELGIKQ IVQGDDYKNQANKQEQSEVSSAVPRGKIYDRNFNAIVTNKALNAITYTRSKSTTQEQR LKIAKKLSDMIKVDTKKVTERDKKDYWILTRPKEAKKLISSKERQQVEDKKISDDDLY QLQLKRITDKQLNELTDKDMQILAIKRQMDSGYALTPQYIKNEDVSAKEMAVVSEHLD ELPGVDVTSDWEREYPYKNLLRSVLGSVSSSNEGLPSNLLDHYLSLGYSRNDRVGKSY LEYQYESLLQGQKAKVENITDSKGNVTGTKTVSEGKAGKDLVLTIDIDLQKSVEKIIE KKLKAAKARPSTELLDRAFVVMMDPRNGEVLTMAGKQIKRENGAYKFDDYALGAMTSS YAMGSAVKGATVLTGLQTGAINLNTVFKDEPLYIGQDKRGKKSWQNLGPVGIQTALEK SSNVFMFKTAIAVGKGEYKPHQALPLDTSAFDTFRNYFSQFGLGVKTGIDLPNEMTGY KGTSRLSGFLLDFAIGQYDTYTPLELAQYVSTIANGGYRMKPQLVKEVRDSNAKKGIG AVVDSVQPEVLNKVDMKSSYIEEVQAGFRRVATKGTAAGQLASASYKPAAKTGTAQSF YDGPDKSKTGTDTYNTTLVAYAPADNPEIAISVVVPWTYIDYNQRYSITNEIGREVMD KYFELKSKQDKEGTQQKNKDKIEENAENTTSSDN*" gene complement(2447369..2449519) /gene="pbpA" /locus_tag="BSU_25000" /old_locus_tag="BSU25000" downshifts complement(2447379) /Source="Nicolas_upshifts" /id="D1295" /incds=0 /nref=255 /ntot=278 /MaxReadThrough="1.22121" /MaxDrop="8.82988" /score="31.2726004" /energy="-10" /TU="U1940" /idTUdmin="U1938" /TUdmin="-6" /isTUend="TRUE" promotor_-10 complement(2448113..2448131) /Source="Nicolas_upshift_promotors" /id="U1938" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.987012987012987" /psig="0.987012987012987" /xcortree=129 /SigmaFactorBS="gcattagagaagtcatcaaacgtttttaTGTTTAAaacagca attgcagtTGGTAAAGGTGAATATAAAcctcaccaagcattgcctttggatacttctg c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2448121) /Source="Nicolas_upshifts" /id="U1938" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.987012987012987" /psig="0.987012987012987" /xcortree=129 /SigmaFactorBS="gcattagagaagtcatcaaacgtttttaTGTTTAAaacagca attgcagtTGGTAAAGGTGAATATAAAcctcaccaagcattgcctttggatacttctg c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(2448147..2448153) /Source="Nicolas_upshift_promotors" /id="U1938" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.987012987012987" /psig="0.987012987012987" /xcortree=129 /SigmaFactorBS="gcattagagaagtcatcaaacgtttttaTGTTTAAaacagca attgcagtTGGTAAAGGTGAATATAAAcctcaccaagcattgcctttggatacttctg c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(2448808..2448827) /Source="Nicolas_upshift_promotors" /id="U1939" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1230 /SigmaFactorBS="tggtaagtgaacatttagacgaactgccaggtgttGATGTCA CGTccgattgggaacgTGAATATCCTTATAAAAACCttcttcgctcagtgctcggaag t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2448825) /Source="Nicolas_upshifts" /id="U1939" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1230 /SigmaFactorBS="tggtaagtgaacatttagacgaactgccaggtgttGATGTCA CGTccgattgggaacgTGAATATCCTTATAAAAACCttcttcgctcagtgctcggaag t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(2448841..2448850) /Source="Nicolas_upshift_promotors" /id="U1939" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1230 /SigmaFactorBS="tggtaagtgaacatttagacgaactgccaggtgttGATGTCA CGTccgattgggaacgTGAATATCCTTATAAAAACCttcttcgctcagtgctcggaag t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(2449569..2449588) /Source="Nicolas_upshift_promotors" /id="U1940" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.773226773226773" /psig="0.994005994005994" /xcortree=2518 /SigmaFactorBS="aatttttttgccaaaaaggggttatcTGTAGaaaaaagtcga aaaaACCTTTAAAATGAAAACTGGcactcttacttgagtgtcttttctttctgtaaat a" /listShort="pbpA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2449574) /Source="Nicolas_upshifts" /id="U1940" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.773226773226773" /psig="0.994005994005994" /xcortree=2518 /SigmaFactorBS="aatttttttgccaaaaaggggttatcTGTAGaaaaaagtcga aaaaACCTTTAAAATGAAAACTGGcactcttacttgagtgtcttttctttctgtaaat a" /listShort="pbpA" /GFF_Attribute="listLong" promotor_-35 complement(2449604..2449608) /Source="Nicolas_upshift_promotors" /id="U1940" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.773226773226773" /psig="0.994005994005994" /xcortree=2518 /SigmaFactorBS="aatttttttgccaaaaaggggttatcTGTAGaaaaaagtcga aaaaACCTTTAAAATGAAAACTGGcactcttacttgagtgtcttttctttctgtaaat a" /listShort="pbpA" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2449633..2450925) /gene="yqgE" /locus_tag="BSU_25010" /old_locus_tag="BSU25010" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 10960106, 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative efflux transporter" /protein_id="NP_390380.2" /db_xref="EnsemblGenomes-Gn:BSU25010" /db_xref="EnsemblGenomes-Tr:CAB14431" /db_xref="GOA:P54487" /db_xref="InterPro:IPR011701" /db_xref="InterPro:IPR020846" /db_xref="InterPro:IPR036259" /db_xref="SubtiList:BG11677" /db_xref="UniProtKB/Swiss-Prot:P54487" /translation="MSKLKKVIGDVDVNKGLLFLLTIGGLYSLGIALSNTFVNVYLWK QSGKFIDLAIYNLSIVTMQPITFYLAGRLAKKIDRVFILRFGVIFLAAFYLSVLLAGE TAASRLVLIGAVLGVGYGFYWLAFNVLTFEITEPDTRDFFNGFMGILSSSAGMIGPIV AGFVISRLENNTGYTVIFSLSLSLFALAVVMSFFLKRRESKGRFMLSKVFGERHSNMN WRRITNAHFFQGLREGIFVFLISVFVFIETNSELALGTFGLVNSAVSFFAYYFASRLI KKKARKKSILLGGLILYGALFLILFHMSFSTLLTYGVFIAIGYPLLLVPYVSLTYDVI GRARHARKARIEYIVLREMFLNAGRIVSILCFLLIVALLKEDVGIPLSLAILGIGHPL IYYFVKDIRFKEKEGENETMEEDGQKRVTEPTLLKGER*" gene complement(2449633..2450925) /gene="yqgE" /locus_tag="BSU_25010" /old_locus_tag="BSU25010" promotor_-10 complement(2450948..2450959) /Source="Nicolas_upshift_promotors" /id="U1941" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=934 /SigmaFactorBS="ggtcctcattatgggaccttgtttttttatgtcttcttttTA CATATctcggtttgagtgAGACAGACTAAGggatagtaaaggggagtcagtaatgagc a" /listShort="yqgE, pbpA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2450959) /Source="Nicolas_upshifts" /id="U1941" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=934 /SigmaFactorBS="ggtcctcattatgggaccttgtttttttatgtcttcttttTA CATATctcggtttgagtgAGACAGACTAAGggatagtaaaggggagtcagtaatgagc a" /listShort="yqgE, pbpA" /GFF_Attribute="listLong" promotor_-35 complement(2450973..2450979) /Source="Nicolas_upshift_promotors" /id="U1941" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=934 /SigmaFactorBS="ggtcctcattatgggaccttgtttttttatgtcttcttttTA CATATctcggtttgagtgAGACAGACTAAGggatagtaaaggggagtcagtaatgagc a" /listShort="yqgE, pbpA" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2451032..2451640) /gene="sodA" /locus_tag="BSU_25020" /old_locus_tag="BSU25020" /EC_number="1.15.1.1" /function="16.8: Protect" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:9393707, 9573176, 9658017, 10074093, 15897454, 18084079, 25445927" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9393707, 9573176, 9658017, 10074093, 15897454, 18084079, 25445927; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="superoxide dismutase (Mn[2+]-dependent)" /protein_id="NP_390381.3" /db_xref="EnsemblGenomes-Gn:BSU25020" /db_xref="EnsemblGenomes-Tr:CAB14432" /db_xref="GOA:P54375" /db_xref="InterPro:IPR001189" /db_xref="InterPro:IPR019831" /db_xref="InterPro:IPR019832" /db_xref="InterPro:IPR019833" /db_xref="InterPro:IPR036314" /db_xref="InterPro:IPR036324" /db_xref="PDB:2RCV" /db_xref="SubtiList:BG11676" /db_xref="UniProtKB/Swiss-Prot:P54375" /translation="MAYELPELPYAYDALEPHIDKETMTIHHTKHHNTYVTNLNKAVE GNTALANKSVEELVADLDSVPENIRTAVRNNGGGHANHKLFWTLLSPNGGGEPTGALA EEINSVFGSFDKFKEQFAAAAAGRFGSGWAWLVVNNGKLEITSTPNQDSPLSEGKTPI LGLDVWEHAYYLNYQNRRPDYISAFWNVVNWDEVARLYSEAK*" gene complement(2451032..2451640) /gene="sodA" /locus_tag="BSU_25020" /old_locus_tag="BSU25020" downshifts complement(2451047) /Source="Nicolas_upshifts" /id="D1296" /incds=0 /nref=265 /ntot=268 /MaxReadThrough="4.329" /MaxDrop="9.16338" /score="3.26408916" /energy="-8.1" /TU="U1943" /idTUdmin="U1942" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(2451692..2451711) /Source="Nicolas_upshift_promotors" /id="U1942" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.671328671328671" /psig="0.998001998001998" /xcortree=102 /SigmaFactorBS="cgctgaaatgagccaaatcgtgagctttttCATTGATTacaa agcattctttTGTTACATTGAATGAAGAAAggctcgctgtgaagcggcatttcagtac a" /listShort="sodA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2451703) /Source="Nicolas_upshifts" /id="U1942" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.671328671328671" /psig="0.998001998001998" /xcortree=102 /SigmaFactorBS="cgctgaaatgagccaaatcgtgagctttttCATTGATTacaa agcattctttTGTTACATTGAATGAAGAAAggctcgctgtgaagcggcatttcagtac a" /listShort="sodA" /GFF_Attribute="listLong" S_feature complement(2451705..2451773) /Source="Nicolas_S_feature" /locus_tag="new_2586107_2586175_c" /HighExp="Etha, Salt, Heat, LPhT, Gly, Sw, S4, LoTm, M9-stat, B36" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigB, SigA" /TUshortPSig="0.997, 1" /TUlongSig="SigB" /TUlongPSig="0.999" /label="S936" promotor_-35 complement(2451726..2451733) /Source="Nicolas_upshift_promotors" /id="U1942" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.671328671328671" /psig="0.998001998001998" /xcortree=102 /SigmaFactorBS="cgctgaaatgagccaaatcgtgagctttttCATTGATTacaa agcattctttTGTTACATTGAATGAAGAAAggctcgctgtgaagcggcatttcagtac a" /listShort="sodA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(2451764..2451782) /Source="Nicolas_upshift_promotors" /id="U1943" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=263 /SigmaFactorBS="tggacggtcctataagaaatgctggcggcaGGTTTAAtgggg cagattatcGGTTAAAGTGAAATATGTCcgctgaaatgagccaaatcgtgagcttttt c" /listShort="S936, sodA, yqgE" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2451773) /Source="Nicolas_upshifts" /id="U1943" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=263 /SigmaFactorBS="tggacggtcctataagaaatgctggcggcaGGTTTAAtgggg cagattatcGGTTAAAGTGAAATATGTCcgctgaaatgagccaaatcgtgagcttttt c" /listShort="S936, sodA, yqgE" /GFF_Attribute="listLong" promotor_-35 complement(2451797..2451803) /Source="Nicolas_upshift_promotors" /id="U1943" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=263 /SigmaFactorBS="tggacggtcctataagaaatgctggcggcaGGTTTAAtgggg cagattatcGGTTAAAGTGAAATATGTCcgctgaaatgagccaaatcgtgagcttttt c" /listShort="S936, sodA, yqgE" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2451819..2452301) /gene="yqgC" /locus_tag="BSU_25030" /old_locus_tag="BSU25030" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 15849754, 16850406; Product type m:membrane component" /codon_start=1 /transl_table=11 /product="conserved integral inner membrane protein of unknown function" /protein_id="NP_390382.1" /db_xref="EnsemblGenomes-Gn:BSU25030" /db_xref="EnsemblGenomes-Tr:CAB14433" /db_xref="GOA:P54486" /db_xref="InterPro:IPR007403" /db_xref="SubtiList:BG11675" /db_xref="UniProtKB/Swiss-Prot:P54486" /translation="MDMLYWLLIAAVFIIAFIGLVYPVIPSVVFIVAGFVLYGFLFSF SPYSYMFWLVEAVFAAVLFAADYVSNLLGVKRFGGSKAAIWGSTIGLLIGPFVIPVAG IILGPFIGAVCAELIVHQKDLKSAFKIGLGSLIGFLTGVIAKGIIQLLMIGYFLWTVL *" gene complement(2451819..2452301) /gene="yqgC" /locus_tag="BSU_25030" /old_locus_tag="BSU25030" S_feature complement(2452302..2452594) /Source="Nicolas_S_feature" /locus_tag="new_2586704_2586996_c" /HighExp="Etha, Gly, Salt, aero, S0, LoTm, HiTm, LPh, nit, ferm" /AntisenseName="yqgB" /AntisenseCor="9.8584854910492598E-2" /AntisenseRegPval="-1" /CDS_PredictionProba="NA" /TUshortSig="SigB, SigA" /TUshortPSig="0.999, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S937" promotor_-35 2452344..2452350 /Source="Nicolas_upshift_promotors" /id="U1944" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.36963036963037" /psig="0.731268731268731" /xcortree=2372 /SigmaFactorBS="ttttactctgtcttcttcatgtcttcCTTGTATtcacacgca tgcaaCGATACAATAAGCAACATATattagtttagctaggaagtgaagatagtgaatg t" /listShort="yqgB, S939" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2452365..2452384 /Source="Nicolas_upshift_promotors" /id="U1944" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.36963036963037" /psig="0.731268731268731" /xcortree=2372 /SigmaFactorBS="ttttactctgtcttcttcatgtcttcCTTGTATtcacacgca tgcaaCGATACAATAAGCAACATATattagtttagctaggaagtgaagatagtgaatg t" /listShort="yqgB, S939" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2452378 /Source="Nicolas_upshifts" /id="U1944" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.36963036963037" /psig="0.731268731268731" /xcortree=2372 /SigmaFactorBS="ttttactctgtcttcttcatgtcttcCTTGTATtcacacgca tgcaaCGATACAATAAGCAACATATattagtttagctaggaagtgaagatagtgaatg t" /listShort="yqgB, S939" /GFF_Attribute="listLong" CDS 2452411..2453178 /gene="yqgB" /locus_tag="BSU_25040" /old_locus_tag="BSU25040" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1c: Function from experimental evidences in the studied genus; PubMedId: 15294815; Product type ph: phenotype" /codon_start=1 /transl_table=11 /product="factor involved in motility" /protein_id="NP_390383.2" /db_xref="EnsemblGenomes-Gn:BSU25040" /db_xref="EnsemblGenomes-Tr:CAB14434" /db_xref="GOA:P54485" /db_xref="InterPro:IPR009574" /db_xref="SubtiList:BG11674" /db_xref="UniProtKB/Swiss-Prot:P54485" /translation="MNVFQLFIKSTYSPRDIAKTRFQGIGKAILYVFLLSVLFAIPTA YYVSTGTVKSMNGFKTVLNKDFPDFTISNGKLQTDEKKATESQANGFVIVFDPTDSYG TEQIEAKQNAIGILQNKFVLAIDGQAQEMSYSMMPSELQKKDVIAGLNQNKAMIVTVL SALIFLVTAAGKFIEVSFLALIGLIIKNSQKKHLSYHQLWKLSAYSITLSTVFFTIMR ALEATVPSEFLLNWFVNFVILFLVLKEIPSKKVINKS*" gene 2452411..2453178 /gene="yqgB" /locus_tag="BSU_25040" /old_locus_tag="BSU25040" promotor_-10 complement(2452592..2452610) /Source="Nicolas_upshift_promotors" /id="U1945" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=174 /SigmaFactorBS="ttttctcatccgtttgaagtttgcCGTTTGAaattgtgaaat caGGGAAATCTTTGTTTAAAAcagttttaaagccgttcattgattttacggtccctgt a" /listShort="S937, yqgC" /listLong="S936, sodA, yqgE" /label="promotor_-10" upshifts complement(2452594) /Source="Nicolas_upshifts" /id="U1945" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=174 /SigmaFactorBS="ttttctcatccgtttgaagtttgcCGTTTGAaattgtgaaat caGGGAAATCTTTGTTTAAAAcagttttaaagccgttcattgattttacggtccctgt a" /listShort="S937, yqgC" /listLong="S936, sodA, yqgE" S_feature complement(2452596..2453532) /Source="Nicolas_S_feature" /locus_tag="new_2586998_2587934_c" /HighExp="S0, S1, aero, M0t45, HPh, Lbtran, LPh, GM 120, nit, M/G" /AntisenseName="yqgB" /AntisenseCor="0.31978785018705103" /AntisenseRegPval="-7.1" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S938" promotor_-35 complement(2452624..2452630) /Source="Nicolas_upshift_promotors" /id="U1945" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=174 /SigmaFactorBS="ttttctcatccgtttgaagtttgcCGTTTGAaattgtgaaat caGGGAAATCTTTGTTTAAAAcagttttaaagccgttcattgattttacggtccctgt a" /listShort="S937, yqgC" /listLong="S936, sodA, yqgE" /label="promotor_-35" S_feature 2453179..2453609 /Source="Nicolas_S_feature" /locus_tag="new_2587581_2588011" /HighExp="C30, HiOs, UNK1, Gly, Fru, S8, Salt, MG 5, S7, MG 25" /AntisenseName="yqgA" /AntisenseCor="0.170248276038857" /AntisenseRegPval="-2.2999999999999998" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.731" /TUlongSig="NA" /TUlongPSig="NA" /label="S939" downshifts 2453566 /Source="Nicolas_upshifts" /id="D1297" /incds=0 /nref=5 /ntot=131 /MaxReadThrough="3.89102" /MaxDrop="3.29021" /score="30.8580926" /energy="-13.8" /TU="U1944" /idTUdmin="U1944" /TUdmin="-88" /isTUend="FALSE" downshifts complement(2453577) /Source="Nicolas_upshifts" /id="D1298" /incds=0 /nref=15 /ntot=207 /MaxReadThrough="6.7306" /MaxDrop="3.9194" /score="7.48192829" /energy="-14.3" /TU="U1947" /idTUdmin="U1945" /TUdmin="-1848" /isTUend="FALSE" CDS complement(2453594..2454022) /gene="yqgA" /locus_tag="BSU_25050" /old_locus_tag="BSU25050" /experiment="publication(s) with functional evidences, PMID:25130749, 27797724" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 25130749, 27797724; Product type ph: phenotype" /codon_start=1 /transl_table=11 /product="cell wall protein" /protein_id="NP_390384.2" /db_xref="EnsemblGenomes-Gn:BSU25050" /db_xref="EnsemblGenomes-Tr:CAB14435" /db_xref="GOA:P54484" /db_xref="SubtiList:BG11673" /db_xref="UniProtKB/Swiss-Prot:P54484" /translation="MKQGKFSVFLILLLMLTLVVAPKEKAEAASSGWQPVSGISGCKI RVITDAYTYTKSATSIDAYAETNGKCGKLNYKSFGVSIVEGGDIGPQYSGYFSSRTPT KKFYFSKLPKPTGTPWAVGLSVYKGKAKGAAFVYINPQKR*" gene complement(2453594..2454022) /gene="yqgA" /locus_tag="BSU_25050" /old_locus_tag="BSU25050" promotor_-35 2454018..2454022 /Source="Nicolas_upshift_promotors" /id="U1946" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp=1 /psig=0 /xcortree=294 /SigmaFactorBS="tagtagcaaaattaaaaacacagaaaattttccttgcTTCAT tttgtagatCCTCCTTTAAACTATtacataattatcctaacagatccattgttcattg t" /listShort="yqfZ" /listLong="S940, ispG" /label="promotor_-35" promotor_-10 2454032..2454046 /Source="Nicolas_upshift_promotors" /id="U1946" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp=1 /psig=0 /xcortree=294 /SigmaFactorBS="tagtagcaaaattaaaaacacagaaaattttccttgcTTCAT tttgtagatCCTCCTTTAAACTATtacataattatcctaacagatccattgttcattg t" /listShort="yqfZ" /listLong="S940, ispG" /label="promotor_-10" upshifts 2454041 /Source="Nicolas_upshifts" /id="U1946" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp=1 /psig=0 /xcortree=294 /SigmaFactorBS="tagtagcaaaattaaaaacacagaaaattttccttgcTTCAT tttgtagatCCTCCTTTAAACTATtacataattatcctaacagatccattgttcattg t" /listShort="yqfZ" /listLong="S940, ispG" promotor_-10 complement(2454045..2454064) /Source="Nicolas_upshift_promotors" /id="U1947" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.994005994005994" /psig=1 /xcortree=2294 /SigmaFactorBS="agatcaaaaagaggcttttataatataaaactcgtattccat TATTTACAatgaacaatggatcTGTTAGGATAATTATGTAATagtttaaaggaggatc t" /listShort="yqgA, S938, S937, yqgC, S936" /listLong="sodA" /label="promotor_-10" upshifts complement(2454068) /Source="Nicolas_upshifts" /id="U1947" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.994005994005994" /psig=1 /xcortree=2294 /SigmaFactorBS="agatcaaaaagaggcttttataatataaaactcgtattccat TATTTACAatgaacaatggatcTGTTAGGATAATTATGTAATagtttaaaggaggatc t" /listShort="yqgA, S938, S937, yqgC, S936" /listLong="sodA" promotor_-35 complement(2454079..2454086) /Source="Nicolas_upshift_promotors" /id="U1947" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.994005994005994" /psig=1 /xcortree=2294 /SigmaFactorBS="agatcaaaaagaggcttttataatataaaactcgtattccat TATTTACAatgaacaatggatcTGTTAGGATAATTATGTAATagtttaaaggaggatc t" /listShort="yqgA, S938, S937, yqgC, S936" /listLong="sodA" /label="promotor_-35" promotor_-35 2454237..2454242 /Source="Nicolas_upshift_promotors" /id="U1948" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=967 /SigmaFactorBS="ccgagcattcgcagtctcttttcttttGTCATGaatcgaaat ggacaaGCATACTATGGTATAAAATttcgtatgcgggaggaaaagcgatgaagcgtct c" /listShort="yqfZ, S940, ispG" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2454258..2454276 /Source="Nicolas_upshift_promotors" /id="U1948" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=967 /SigmaFactorBS="ccgagcattcgcagtctcttttcttttGTCATGaatcgaaat ggacaaGCATACTATGGTATAAAATttcgtatgcgggaggaaaagcgatgaagcgtct c" /listShort="yqfZ, S940, ispG" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2454270 /Source="Nicolas_upshifts" /id="U1948" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=967 /SigmaFactorBS="ccgagcattcgcagtctcttttcttttGTCATGaatcgaaat ggacaaGCATACTATGGTATAAAATttcgtatgcgggaggaaaagcgatgaagcgtct c" /listShort="yqfZ, S940, ispG" /GFF_Attribute="listLong" CDS 2454299..2454598 /gene="yqfZ" /locus_tag="BSU_25060" /old_locus_tag="BSU25060" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 15294815; Product type ph : phenotype" /codon_start=1 /transl_table=11 /product="factor involved in motility" /protein_id="NP_390385.1" /db_xref="EnsemblGenomes-Gn:BSU25060" /db_xref="EnsemblGenomes-Tr:CAB14436" /db_xref="GOA:P54483" /db_xref="InterPro:IPR018392" /db_xref="InterPro:IPR020506" /db_xref="InterPro:IPR036779" /db_xref="SubtiList:BG11672" /db_xref="UniProtKB/Swiss-Prot:P54483" /translation="MKRLTLVCSIVFILFILFYDLKIGTIPIQDLPVYEASAKTAVQE PAYKTVKVKPGDTVMSIVGSAGSPDDIVKDFEALNPNVKANAIQAGTAYKFPVYP*" gene 2454299..2454598 /gene="yqfZ" /locus_tag="BSU_25060" /old_locus_tag="BSU25060" promotor_-35 2454611..2454618 /Source="Nicolas_upshift_promotors" /id="U1949" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.613386613386613" /psig="0.999000999001" /xcortree=1976 /SigmaFactorBS="ccggtctacccttaatttaacgttaatTTCTTGTCagttcgg cgaagacACTGTTACAATGTAATTTGTaaaataaattcacataaaccatactagaatt g" /listShort="S940, ispG" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2454633..2454652 /Source="Nicolas_upshift_promotors" /id="U1949" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.613386613386613" /psig="0.999000999001" /xcortree=1976 /SigmaFactorBS="ccggtctacccttaatttaacgttaatTTCTTGTCagttcgg cgaagacACTGTTACAATGTAATTTGTaaaataaattcacataaaccatactagaatt g" /listShort="S940, ispG" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 2454644..2454720 /Source="Nicolas_S_feature" /locus_tag="new_2589046_2589122" /HighExp="Diami, dia5, dia15, H2O2, Etha, Salt, LBGexp, Oxctl, Paraq, dia0" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigEF" /TUshortPSig="0.999, 1" /TUlongSig="Sig-" /TUlongPSig=0 /label="S940" upshifts 2454644 /Source="Nicolas_upshifts" /id="U1949" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.613386613386613" /psig="0.999000999001" /xcortree=1976 /SigmaFactorBS="ccggtctacccttaatttaacgttaatTTCTTGTCagttcgg cgaagacACTGTTACAATGTAATTTGTaaaataaattcacataaaccatactagaatt g" /listShort="S940, ispG" /GFF_Attribute="listLong" CDS 2454721..2455854 /gene="ispG" /locus_tag="BSU_25070" /old_locus_tag="BSU25070" /EC_number="1.17.7.1" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 12571359, 16268586, 25212876; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase)" /protein_id="NP_390386.1" /db_xref="EnsemblGenomes-Gn:BSU25070" /db_xref="EnsemblGenomes-Tr:CAB14437" /db_xref="GOA:P54482" /db_xref="InterPro:IPR004588" /db_xref="InterPro:IPR011005" /db_xref="InterPro:IPR016425" /db_xref="InterPro:IPR036849" /db_xref="SubtiList:BG11671" /db_xref="UniProtKB/Swiss-Prot:P54482" /translation="MQVSEITHRTKTRPVKVGPLTIGGNNEVVIQSMTTTKTHDVEAT VAEINRLAEAGCQIVRVACPDERAANAIADIKKRISIPLVVDIHFDYKLALKAIEGGA DKIRINPGNIGRREKVEAVVKAAKDKGIPIRIGVNAGSLEKRILEKYGYPTADGMVES ALHHIKILEDLDFHDIIVSMKASDVNLAIEAYEKAAKAFDYPLHLGITESGTLFAGTV KSAAGLGAILSKGIGNTMRISLSADPVEEVKVARELLKSFGLASNAATLISCPTCGRI EIDLISIANEVEEYISKIKAPIKVAVLGCAVNGPGEAREADIGIAGARGEGLLFRKGK IVRKVPEETMVEELKKEIDILAEEHYAKLEAEKAKLKEETQKA*" gene 2454721..2455854 /gene="ispG" /locus_tag="BSU_25070" /old_locus_tag="BSU25070" downshifts 2455835 /Source="Nicolas_upshifts" /id="D1299" /incds=0 /nref=230 /ntot=267 /MaxReadThrough="2.62035" /MaxDrop="8.92434" /score="30.8580926" /energy="-13.8" /TU="NA" /idTUdmin="U1948" /TUdmin=3 /isTUend="TRUE" CDS complement(2455880..2456269) /gene="yqfX" /locus_tag="BSU_25080" /old_locus_tag="BSU25080" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 17322312, 22882546" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function expressed in germinating spores" /protein_id="NP_390387.1" /db_xref="EnsemblGenomes-Gn:BSU25080" /db_xref="EnsemblGenomes-Tr:CAB14438" /db_xref="GOA:P54481" /db_xref="SubtiList:BG11670" /db_xref="UniProtKB/Swiss-Prot:P54481" /translation="MKVANDYEKRDNNSYYVDHGSEGTNITRDNDGFFEETAAEIAEP YRAADRSNDQDNDRSGGNVNEGRGIGYIALALSIISLFVLPVLLGAAGIIVGYIARRR GAQGLGAWAMGIGVVSLVLGIFIIPFF*" gene complement(2455880..2456269) /gene="yqfX" /locus_tag="BSU_25080" /old_locus_tag="BSU25080" downshifts complement(2455906) /Source="Nicolas_upshifts" /id="D1300" /incds=0 /nref=10 /ntot=62 /MaxReadThrough="1.85077" /MaxDrop="8.74353" /score="28.1764525" /energy="-13.8" /TU="NA" /idTUdmin="U1950" /TUdmin=2 /isTUend="TRUE" promotor_-10 complement(2456300..2456311) /Source="Nicolas_upshift_promotors" /id="U1950" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=841 /SigmaFactorBS="ataaacaattgacattaacagaaaagtttagcaAACATGAat caggcaaaatgGATCAAACTATAaaagctcctttaataaaacagaagggggaattgaa g" /listShort="yqfX" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2456304) /Source="Nicolas_upshifts" /id="U1950" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=841 /SigmaFactorBS="ataaacaattgacattaacagaaaagtttagcaAACATGAat caggcaaaatgGATCAAACTATAaaagctcctttaataaaacagaagggggaattgaa g" /listShort="yqfX" /GFF_Attribute="listLong" promotor_-35 complement(2456325..2456331) /Source="Nicolas_upshift_promotors" /id="U1950" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=841 /SigmaFactorBS="ataaacaattgacattaacagaaaagtttagcaAACATGAat caggcaaaatgGATCAAACTATAaaagctcctttaataaaacagaagggggaattgaa g" /listShort="yqfX" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 2456344..2456351 /Source="Nicolas_upshift_promotors" /id="U1951" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.971028971028971" /psig="0.999000999001" /xcortree=587 /SigmaFactorBS="agtttgatccattttgcctgattcatgtttgctaaacttttC TGTTAATgtcaattgttTATGTTACACTTGAAGGGATgaaactgaaggagtgtgggca t" /listShort="yqfW, S941" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2456362..2456381 /Source="Nicolas_upshift_promotors" /id="U1951" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.971028971028971" /psig="0.999000999001" /xcortree=587 /SigmaFactorBS="agtttgatccattttgcctgattcatgtttgctaaacttttC TGTTAATgtcaattgttTATGTTACACTTGAAGGGATgaaactgaaggagtgtgggca t" /listShort="yqfW, S941" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2456363 /Source="Nicolas_upshifts" /id="U1951" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.971028971028971" /psig="0.999000999001" /xcortree=587 /SigmaFactorBS="agtttgatccattttgcctgattcatgtttgctaaacttttC TGTTAATgtcaattgttTATGTTACACTTGAAGGGATgaaactgaaggagtgtgggca t" /listShort="yqfW, S941" /GFF_Attribute="listLong" CDS 2456402..2456983 /gene="yqfW" /locus_tag="BSU_25090" /old_locus_tag="BSU25090" /EC_number="3.1.3.-" /function="16.11: Scavenge (Catabolism)" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative nucleotidase" /protein_id="NP_390388.1" /db_xref="EnsemblGenomes-Gn:BSU25090" /db_xref="EnsemblGenomes-Tr:CAB14439" /db_xref="GOA:P54480" /db_xref="InterPro:IPR009206" /db_xref="InterPro:IPR023214" /db_xref="InterPro:IPR036412" /db_xref="SubtiList:BG11669" /db_xref="UniProtKB/Swiss-Prot:P54480" /translation="MLRLGIDIDGTITAQDTFVPYLNRSFNLSISLNDMTDYDLTKLL NITQEEFWDWMNQNEAIIYKEALLAQHAKQSLDLLKEEHKLIYITARRTHLTDITYEW FDRQNIHYDHIELVGGHHKVEAVKNHNIDLFFEDHHGNAMMIAKEAGIPVILFNSPYN QLPIDSNIIRVNNWLEAVQWMNNNKHHLIRVNN*" gene 2456402..2456983 /gene="yqfW" /locus_tag="BSU_25090" /old_locus_tag="BSU25090" downshifts 2456981 /Source="Nicolas_upshifts" /id="D1301" /incds=0 /nref=34 /ntot=240 /MaxReadThrough="4.07255" /MaxDrop="4.44714" /score="-2.90660182" /energy="-8" /TU="U1951" /idTUdmin="U1951" /TUdmin="-611" /isTUend="FALSE" S_feature 2457026..2457634 /Source="Nicolas_S_feature" /locus_tag="new_2591428_2592036" /HighExp="LoTm, S8, Cold, S7, S5, Sw, BC, S6, HiOs, B60" /AntisenseName="zur" /AntisenseCor="-0.265512398914523" /AntisenseRegPval="-5" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S941" CDS complement(2457026..2457463) /gene="zur" /locus_tag="BSU_25100" /old_locus_tag="BSU25100" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:12180919, 12426338, 12904577, 17216355, 21821657, 25213752, 27561249, 28104400" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12180919, 12426338, 12904577, 17216355, 21821657, 25213752, 27561249, 28104400; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator (Zn[2+]-binding Fur family)" /protein_id="NP_390389.2" /db_xref="EnsemblGenomes-Gn:BSU25100" /db_xref="EnsemblGenomes-Tr:CAB14440" /db_xref="GOA:P54479" /db_xref="InterPro:IPR002481" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG11668" /db_xref="UniProtKB/Swiss-Prot:P54479" /translation="MNVQEALNLLKENGYKYTNKREDMLQLFADSDRYLTAKNVLSAL NDDYPGLSFDTIYRNLSLYEELGILETTELSGEKLFRFKCSFTHHHHHFICLACGKTK EIESCPMDKLCDDLDGYQVSGHKFEIYGTCPDCTAENQENTTA*" gene complement(2457026..2457463) /gene="zur" /locus_tag="BSU_25100" /old_locus_tag="BSU25100" downshifts complement(2457030) /Source="Nicolas_upshifts" /id="D1302" /incds=0 /nref=181 /ntot=243 /MaxReadThrough="2.37371" /MaxDrop="6.74703" /score="16.4418277" /energy="-11.9" /TU="U1956" /idTUdmin="U1952" /TUdmin=0 /isTUend="TRUE" S_feature complement(2457464..2457558) /Source="Nicolas_S_feature" /locus_tag="new_2591866_2591960_c" /HighExp="LPhT, G180, Cold, LBGstat, H2O2, Oxctl, G135, G150, HPh, Lbtran" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA, SigA" /TUshortPSig="1, 1, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S942" promotor_-10 complement(2457554..2457573) /Source="Nicolas_upshift_promotors" /id="U1952" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.428571428571429" /psig=1 /xcortree=2760 /SigmaFactorBS="aaaaacgcaatccactaggctttCATTTACTtttattcattt tatGGGTATAATTTTATCTGCAGtaaagaaaatggcttgctggacagacagctgccat t" /listShort="S942, zur" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2457558) /Source="Nicolas_upshifts" /id="U1952" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.428571428571429" /psig=1 /xcortree=2760 /SigmaFactorBS="aaaaacgcaatccactaggctttCATTTACTtttattcattt tatGGGTATAATTTTATCTGCAGtaaagaaaatggcttgctggacagacagctgccat t" /listShort="S942, zur" /GFF_Attribute="listLong" promotor_-35 complement(2457588..2457595) /Source="Nicolas_upshift_promotors" /id="U1952" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.428571428571429" /psig=1 /xcortree=2760 /SigmaFactorBS="aaaaacgcaatccactaggctttCATTTACTtttattcattt tatGGGTATAATTTTATCTGCAGtaaagaaaatggcttgctggacagacagctgccat t" /listShort="S942, zur" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2457601..2458482) /gene="yqfU" /locus_tag="BSU_25110" /old_locus_tag="BSU25110" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative integral inner membrane protein" /protein_id="NP_390390.2" /db_xref="EnsemblGenomes-Gn:BSU25110" /db_xref="EnsemblGenomes-Tr:CAB14441" /db_xref="GOA:P54478" /db_xref="InterPro:IPR003740" /db_xref="InterPro:IPR019264" /db_xref="SubtiList:BG11667" /db_xref="UniProtKB/Swiss-Prot:P54478" /translation="MTPTKQHKKETFTHFIFRVFMILVGAASAAVSIELFLIPNDFID GGIIGVSLILDHLFMSNPFLNFAFFVVILNIPFMIFGYKYIGKTFLVSTFIGIVGLAV IESSLHHVEAITTQPILATVFGGLLLGFGVGLVIRNGGSMDGTEILGILLTKKLPFSV GEFVMFINVFIFIWAVFVFGPEQAMYSFMTYYIAMKTIDAVIQGLDETKAVIIVSEQY DEISDAILHRLGRGTTKLKGKGGYTDEEKDVIYAVVTRLEVTKLKSIVFEVDQNAFIT IMNTHETRGGKFKNAIH*" gene complement(2457601..2458482) /gene="yqfU" /locus_tag="BSU_25110" /old_locus_tag="BSU25110" promotor_-35 2458478..2458483 /Source="Nicolas_upshift_promotors" /id="U1953" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.948051948051948" /psig="0.948051948051948" /xcortree=1102 /SigmaFactorBS="ctttcttatgttgttttgttgggGTCATAaaatctcctttcc tgCAATAACTATTTTAAATACattataaatctattttaccattaaacactgacacatt t" /listShort="yqfT, S944" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2458499..2458517 /Source="Nicolas_upshift_promotors" /id="U1953" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.948051948051948" /psig="0.948051948051948" /xcortree=1102 /SigmaFactorBS="ctttcttatgttgttttgttgggGTCATAaaatctcctttcc tgCAATAACTATTTTAAATACattataaatctattttaccattaaacactgacacatt t" /listShort="yqfT, S944" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2458515 /Source="Nicolas_upshifts" /id="U1953" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.948051948051948" /psig="0.948051948051948" /xcortree=1102 /SigmaFactorBS="ctttcttatgttgttttgttgggGTCATAaaatctcctttcc tgCAATAACTATTTTAAATACattataaatctattttaccattaaacactgacacatt t" /listShort="yqfT, S944" /GFF_Attribute="listLong" misc_feature complement(2458520..2458539) /Source="Nicolas_upshift_promotors" /id="U1954" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.706293706293706" /psig=1 /xcortree=2995 /SigmaFactorBS="cctccagacttaatgtatgggcaaatcagtaaaatgtgtcag tgtttAATGGTAAAATAGATTTATAatgtatttaaaatagttattgcaggaaaggaga t" /listShort="yqfU, S942, zur" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(2458526) /Source="Nicolas_upshifts" /id="U1954" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.706293706293706" /psig=1 /xcortree=2995 /SigmaFactorBS="cctccagacttaatgtatgggcaaatcagtaaaatgtgtcag tgtttAATGGTAAAATAGATTTATAatgtatttaaaatagttattgcaggaaaggaga t" /listShort="yqfU, S942, zur" /GFF_Attribute="listLong" S_feature complement(2458528..2458855) /Source="Nicolas_S_feature" /locus_tag="new_2592930_2593257_c" /HighExp="Cold, T-4.40H, T-5.40H, Salt, GM-0.1, BMM, UNK1, MG 25, GM-0.2, SMM" /AntisenseName="yqfT" /AntisenseCor="-0.62379514374156597" /AntisenseRegPval="-29.7" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S943" promotor_-35 2458544..2458553 /Source="Nicolas_upshift_promotors" /id="U1955" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1273 /SigmaFactorBS="aataactattttaaatacattataaatctattttaccattaa acACTGACACATtttactgatttgCCCATACATTAAGTCTGGAGgtggaatgaccgat g" /listShort="yqfT" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 2458560 /Source="Nicolas_upshifts" /id="U1955" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1273 /SigmaFactorBS="aataactattttaaatacattataaatctattttaccattaa acACTGACACATtttactgatttgCCCATACATTAAGTCTGGAGgtggaatgaccgat g" /listShort="yqfT" /GFF_Attribute="listLong" promotor_-10 2458566..2458585 /Source="Nicolas_upshift_promotors" /id="U1955" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1273 /SigmaFactorBS="aataactattttaaatacattataaatctattttaccattaa acACTGACACATtttactgatttgCCCATACATTAAGTCTGGAGgtggaatgaccgat g" /listShort="yqfT" /GFF_Attribute="listLong" /label="promotor_-10" CDS 2458598..2458852 /gene="yqfT" /locus_tag="BSU_25120" /old_locus_tag="BSU25120" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_390391.1" /db_xref="EnsemblGenomes-Gn:BSU25120" /db_xref="EnsemblGenomes-Tr:CAB14442" /db_xref="InterPro:IPR020277" /db_xref="SubtiList:BG11666" /db_xref="UniProtKB/Swiss-Prot:P54477" /translation="MILFQRIILQRLNQATADDLLKYSKQYGISLTRSQAVEVANLLY GKNVNIFNESERMRLLKQVETITSKETAQTVNELFKQFTS*" gene 2458598..2458852 /gene="yqfT" /locus_tag="BSU_25120" /old_locus_tag="BSU25120" downshifts 2458839 /Source="Nicolas_upshifts" /id="D1303" /incds=0 /nref=12 /ntot=72 /MaxReadThrough="3.97414" /MaxDrop="7.03976" /score="24.5413663" /energy="-9.8" /TU="U1953" /idTUdmin="U1955" /TUdmin="-7" /isTUend="TRUE" CDS complement(2458879..2459772) /gene="nfo" /locus_tag="BSU_25130" /old_locus_tag="BSU25130" /EC_number="3.1.21.2" /function="16.8: Protect" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:12486072, 12949090, 16237020, 18203828, 19930460, 21441501, 24123749, 24244006, 24914186" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12486072, 12949090, 16237020, 18203828, 19930460, 21441501, 24123749, 24244006, 24914186; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="type IV apurinic/apyrimidinic endonuclease" /protein_id="NP_390392.1" /db_xref="EnsemblGenomes-Gn:BSU25130" /db_xref="EnsemblGenomes-Tr:CAB14443" /db_xref="GOA:P54476" /db_xref="InterPro:IPR001719" /db_xref="InterPro:IPR013022" /db_xref="InterPro:IPR018246" /db_xref="InterPro:IPR036237" /db_xref="SubtiList:BG11665" /db_xref="UniProtKB/Swiss-Prot:P54476" /translation="MLRIGSHVSMSGKHMLLAASQEAVSYGANTFMIYTGAPQNTRRK KIEDLNIEAGRAHMQENGIDEIIVHAPYIINIGNTTNPSTFELGVDFLRSEIERTAAI GAKQIVLHPGAHVGAGAEAGIKKIIEGLNEVIDPNQNVQIALETMAGKGSECGRSFEE LAQIIEGVTHNEQLSVCFDTCHTHDAGYNIVEDFDGVLNEFDKIIGIDRIKVLHINDS KNVKGARKDRHENIGFGEIGFDALQYVVHHEQLKDIPKILETPYVGEDKKNKKPPYRF EIEMLKEKQFDDTLLEKILQQ*" gene complement(2458879..2459772) /gene="nfo" /locus_tag="BSU_25130" /old_locus_tag="BSU25130" S_feature 2458884..2459685 /Source="Nicolas_S_feature" /locus_tag="new_2593286_2594087" /HighExp="S6, S7, C30, S8, S5, G135, C90, Gly, LoTm, Sw" /AntisenseName="nfo" /AntisenseCor="-0.36683479556464399" /AntisenseRegPval="-9.3000000000000007" /CDS_PredictionProba="NA" /TUshortSig="SigEF" /TUshortPSig="0.948" /TUlongSig="NA" /TUlongPSig="NA" /label="S944" downshifts complement(2458900) /Source="Nicolas_upshifts" /id="D1304" /incds=0 /nref=46 /ntot=187 /MaxReadThrough="4.82641" /MaxDrop="6.05328" /score="16.7756411" /energy="-9.8" /TU="U1956" /idTUdmin="U1952" /TUdmin="-1870" /isTUend="FALSE" CDS complement(2459782..2461098) /gene="cshB" /locus_tag="BSU_25140" /old_locus_tag="BSU25140" /EC_number="3.6.1.-" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:16014871, 16352840, 18203828, 20572937, 23175651" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16014871, 16352840, 18203828, 20572937, 23175651; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="ATP-dependent RNA helicase; cold shock" /protein_id="NP_390393.1" /db_xref="EnsemblGenomes-Gn:BSU25140" /db_xref="EnsemblGenomes-Tr:CAB14444" /db_xref="GOA:P54475" /db_xref="InterPro:IPR001650" /db_xref="InterPro:IPR011545" /db_xref="InterPro:IPR014001" /db_xref="InterPro:IPR014014" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR030881" /db_xref="SubtiList:BG11664" /db_xref="UniProtKB/Swiss-Prot:P54475" /translation="MKETKFELYELKPFIIDAVHRLGFYEPTDIQKRLIPAVLKKESV IGQSQTGTGKTHAYLLPLLNKIDPAKDVVQVVITAPTRELANQIYQEALKITQGEEGS QIRSKCFIGGTDKQKSIDKLKIQPHLVVGTPGRIADLIKEQALSVHKAESLVIDEADL MLDMGFLADVDYIGSRMPEDLQMLVFSATIPEKLKPFLKKYMENPKYAHVEPKQVTAA KIEHILIPSKHRDKDKLLFDIMSHLNPYLGIVFANTKNTADHIAQYLTGKGMKIGLLH GGLTPRERKKVMKQINDLEFTYIIATDLAARGIDIKGVSHVINYELPDDLDFYVHRVG RTARAGSSGQAMTIYELTDEDALVRLEKMGIEFEYLELEKGEWKKGDDRQRRKKRKKT PNEADEIAHRLVKKPKKVKPGYKKKMSYEMEKIKKKQRRNQSKKRK*" gene complement(2459782..2461098) /gene="cshB" /locus_tag="BSU_25140" /old_locus_tag="BSU25140" promotor_-10 complement(2461134..2461153) /Source="Nicolas_upshift_promotors" /id="U1956" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.683316683316683" /psig=1 /xcortree=2492 /SigmaFactorBS="tacataactgaataaaacaaacgccttgcaaaCGTGGtgttt ttaagcaaaaTCGGGTATAATGTGATGATGgacacataatgtgccgctttaaggagct g" /listShort="cshB, nfo, S943, yqfU, S942, zur" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2461145) /Source="Nicolas_upshifts" /id="U1956" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.683316683316683" /psig=1 /xcortree=2492 /SigmaFactorBS="tacataactgaataaaacaaacgccttgcaaaCGTGGtgttt ttaagcaaaaTCGGGTATAATGTGATGATGgacacataatgtgccgctttaaggagct g" /listShort="cshB, nfo, S943, yqfU, S942, zur" /GFF_Attribute="listLong" promotor_-35 complement(2461169..2461173) /Source="Nicolas_upshift_promotors" /id="U1956" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.683316683316683" /psig=1 /xcortree=2492 /SigmaFactorBS="tacataactgaataaaacaaacgccttgcaaaCGTGGtgttt ttaagcaaaaTCGGGTATAATGTGATGATGgacacataatgtgccgctttaaggagct g" /listShort="cshB, nfo, S943, yqfU, S942, zur" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 2461202..2461211 /Source="Nicolas_upshift_promotors" /id="U1957" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1300 /SigmaFactorBS="aaaacaccacgtttgcaaggcgtttgttttattcagttaTGT AAAGCAAataccgcagcccaTGCATATTCTAATAGCAGAGagagctgaaaggaggtac a" /listShort="yqfQ, S945, ispH" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 2461223 /Source="Nicolas_upshifts" /id="U1957" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1300 /SigmaFactorBS="aaaacaccacgtttgcaaggcgtttgttttattcagttaTGT AAAGCAAataccgcagcccaTGCATATTCTAATAGCAGAGagagctgaaaggaggtac a" /listShort="yqfQ, S945, ispH" /GFF_Attribute="listLong" promotor_-10 2461225..2461244 /Source="Nicolas_upshift_promotors" /id="U1957" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1300 /SigmaFactorBS="aaaacaccacgtttgcaaggcgtttgttttattcagttaTGT AAAGCAAataccgcagcccaTGCATATTCTAATAGCAGAGagagctgaaaggaggtac a" /listShort="yqfQ, S945, ispH" /GFF_Attribute="listLong" /label="promotor_-10" CDS 2461267..2462010 /gene="yqfQ" /locus_tag="BSU_25150" /old_locus_tag="BSU25150" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_390394.1" /db_xref="EnsemblGenomes-Gn:BSU25150" /db_xref="EnsemblGenomes-Tr:CAB14445" /db_xref="InterPro:IPR025571" /db_xref="SubtiList:BG11663" /db_xref="UniProtKB/Swiss-Prot:P54474" /translation="MFSPQQPMRNYPQPGPPRPMPNQRMMGRRPPNMRGPSFGAQQQG FQQAGQFLPQANAGARNGAGAGGGLKGMLSRFLPGGGGAGSAGVPGIPGAGAAASGGA GLQGIQNIANPASLSSMLGNVQKVLGMAQQVTPMIQQYGPLVRNLPAMMKLYSQLSKS DDTETEANEESEKQSVSEESSEKEKETETKTSDGNKKSKPKSSSLPKKSKTTDNKEQE LKTSAPKKKEAASPAPKRTSGSSKPRLYI*" gene 2461267..2462010 /gene="yqfQ" /locus_tag="BSU_25150" /old_locus_tag="BSU25150" downshifts 2461992 /Source="Nicolas_upshifts" /id="D1305" /incds=0 /nref=1 /ntot=27 /MaxReadThrough="5.46594" /MaxDrop="3.2445" /score="4.32537428" /energy="-6.8" /TU="U1957" /idTUdmin="U1957" /TUdmin="-1056" /isTUend="FALSE" promotor_-35 2462014..2462021 /Source="Nicolas_upshift_promotors" /id="U1958" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.473526473526474" /psig=1 /xcortree=2580 /SigmaFactorBS="atcaggcagttcaaaaccgagattatatatttaacatTCTTT GATatcttaagtgagaTTGGCTATAATGAGATCAGAagaatgcaagaatagagccgtt t" /listShort="S945, ispH" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2462035..2462054 /Source="Nicolas_upshift_promotors" /id="U1958" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.473526473526474" /psig=1 /xcortree=2580 /SigmaFactorBS="atcaggcagttcaaaaccgagattatatatttaacatTCTTT GATatcttaagtgagaTTGGCTATAATGAGATCAGAagaatgcaagaatagagccgtt t" /listShort="S945, ispH" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 2462037..2462132 /Source="Nicolas_S_feature" /locus_tag="new_2596439_2596534" /HighExp="S8, S7, S6, Cold, H2O2, Salt, dia15, G180, Paraq, G135" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigK" /TUshortPSig="1, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S945" upshifts 2462037 /Source="Nicolas_upshifts" /id="U1958" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.473526473526474" /psig=1 /xcortree=2580 /SigmaFactorBS="atcaggcagttcaaaaccgagattatatatttaacatTCTTT GATatcttaagtgagaTTGGCTATAATGAGATCAGAagaatgcaagaatagagccgtt t" /listShort="S945, ispH" /GFF_Attribute="listLong" CDS 2462133..2463077 /gene="ispH" /locus_tag="BSU_25160" /old_locus_tag="BSU25160" /EC_number="1.17.7.4" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 12682299, 12706830, 15381396, 15469281, 17458547, 27169371; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate reductase" /protein_id="NP_390395.2" /db_xref="EnsemblGenomes-Gn:BSU25160" /db_xref="EnsemblGenomes-Tr:CAB14446" /db_xref="GOA:P54473" /db_xref="InterPro:IPR003451" /db_xref="SubtiList:BG11662" /db_xref="UniProtKB/Swiss-Prot:P54473" /translation="MDVIKISPRGYCYGVVDAMVIAKNASLDKSLPRPIYILGMIVHN KHVTDAFEEEGIFTLDGSNRLDILKQVDKGTVIFTAHGVSPEVRRIAEEKGLVAIDAT CPDVTKTHNLILEMKEKGYHVIYIGKKGHPEPEGAVGVAPEIVHLVETEEDVKNLDIQ SEKLIVTNQTTMSQWDVHDIMELVKEKYPHVEYHQEICLATQVRQEAVSEQAKKADLT IVVGDPKSNNSNRLAQVSEEIAGTKAYRIGDLSELKLEWLKGVNTVAVTAGASTPTPI TKEVIRFLEQFDHEDPSTWTTEHNIPLKKILPKVKAKN*" gene 2462133..2463077 /gene="ispH" /locus_tag="BSU_25160" /old_locus_tag="BSU25160" downshifts 2463048 /Source="Nicolas_upshifts" /id="D1306" /incds=0 /nref=106 /ntot=243 /MaxReadThrough="4.04288" /MaxDrop="5.66904" /score="29.529951" /energy="-12.2" /TU="U1958" /idTUdmin="U1957" /TUdmin=0 /isTUend="TRUE" CDS complement(2463100..2464221) /gene="yqfO" /locus_tag="BSU_25170" /old_locus_tag="BSU25170" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 17187687, 17586767; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative GTP cyclohydrolase" /protein_id="NP_390396.1" /db_xref="EnsemblGenomes-Gn:BSU25170" /db_xref="EnsemblGenomes-Tr:CAB14447" /db_xref="GOA:P54472" /db_xref="InterPro:IPR002678" /db_xref="InterPro:IPR015867" /db_xref="InterPro:IPR017221" /db_xref="InterPro:IPR036069" /db_xref="SubtiList:BG11661" /db_xref="UniProtKB/Swiss-Prot:P54472" /translation="MAKSVNGQQIIQLFEQFSPKAYAVEGDKIGLQIGTLNKPIKNVM VTLDVLESVIDEAIEKEVDLIIAHHPPIFRSLKHISTDQPAGRLIEKCLKHDIAVYAA HTNLDVADGGVNDLLAEALELSETEVLAPTYTDPLKKLAVYVPKEYEEQVRAALGNAG AGHIGEYSHCAFSSEGIGSFKPLDGAKPFIGEVGELELVHEVRLETVFPKSVEKAVIN AMIKSHPYEEVAYDIYPVEQTPAEKGLGRVGTLKNEMTLKEFALFVKDKLDVNGVRMV GDADSMVKKVAVLGGDGNKYIHHAKRKGADVYVTGDLYFHVAHDAMMLGLNVVDPGHY AEKIMKEGVTRKLTSMCNDKKFGVNIFVSETDTNPFTFL*" gene complement(2463100..2464221) /gene="yqfO" /locus_tag="BSU_25170" /old_locus_tag="BSU25170" downshifts complement(2463125) /Source="Nicolas_upshifts" /id="D1307" /incds=0 /nref=63 /ntot=224 /MaxReadThrough="3.241" /MaxDrop="4.76436" /score="27.9821938" /energy="-12.2" /TU="NA" /idTUdmin="U1959" /TUdmin="-1" /isTUend="TRUE" CDS complement(2464214..2464864) /gene="trmK" /locus_tag="BSU_25180" /old_locus_tag="BSU25180" /EC_number="2.1.1.217" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:18420655, 27098549" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 18420655, 27098549; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="tRNA (adenine(22)-N(1))-methyltransferase" /protein_id="NP_390397.1" /db_xref="EnsemblGenomes-Gn:BSU25180" /db_xref="EnsemblGenomes-Tr:CAB14448" /db_xref="GOA:P54471" /db_xref="InterPro:IPR006901" /db_xref="InterPro:IPR029063" /db_xref="SubtiList:BG11660" /db_xref="UniProtKB/Swiss-Prot:P54471" /translation="MADIGSDHAYLPCYAVLNHKASGAIAGEITDGPFLSAKRQVEKS GLNSHISVRQGDGLEVIKKGEADAITIAGMGGALIAHILEAGKDKLTGKERLILQPNI HAVHIREWLYKERYALIDEVILEEDGKCYEVLVAEAGDRDAAYDGISLSAGMLVGPFL AKEKNAVFLKKWTQELQHTQSIYEQISQAADTEQNKQKLKELADRMELLKEVIDHG*" gene complement(2464214..2464864) /gene="trmK" /locus_tag="BSU_25180" /old_locus_tag="BSU25180" S_feature complement(2464865..2464973) /Source="Nicolas_S_feature" /locus_tag="new_2599267_2599375_c" /HighExp="LBGexp, LBGtran, dia15, dia0, Lbexp, G150, G180, LBGstat, Oxctl, H2O2" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA, SigA" /TUshortPSig="1, 0.98, 0.998" /TUlongSig="SigH, SigEF, SigA, SigA, SigA, SigA, SigA" /TUlongPSig="1, 0.974, 0.979, 1, 1, 0.999, 0.998" /label="S946" promotor_-10 complement(2464961..2464980) /Source="Nicolas_upshift_promotors" /id="U1959" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.933066933066933" /psig=1 /xcortree=2573 /SigmaFactorBS="tcaaaagaaataatttcaaaatcatttgcttcaGCTTGgatt ccgggctgattTTTTATATGATAGTAAAGGAaaaaatgattgagaaaagttgtgatga c" /listShort="S946, trmK, yqfO" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2464973) /Source="Nicolas_upshifts" /id="U1959" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.933066933066933" /psig=1 /xcortree=2573 /SigmaFactorBS="tcaaaagaaataatttcaaaatcatttgcttcaGCTTGgatt ccgggctgattTTTTATATGATAGTAAAGGAaaaaatgattgagaaaagttgtgatga c" /listShort="S946, trmK, yqfO" /GFF_Attribute="listLong" S_feature complement(2464975..2465088) /Source="Nicolas_S_feature" /locus_tag="new_2599377_2599490_c" /HighExp="Lbstat, M0t90, M9-stat, S2, T1.0H, T1.30H, T2.30H, T3.0H, S7, T2.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="0.98, 0.998" /TUlongSig="SigH, SigEF, SigA, SigA, SigA, SigA, SigA" /TUlongPSig="1, 0.974, 0.979, 1, 1, 0.999, 0.998" /label="S947" promotor_-35 complement(2464996..2465000) /Source="Nicolas_upshift_promotors" /id="U1959" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.933066933066933" /psig=1 /xcortree=2573 /SigmaFactorBS="tcaaaagaaataatttcaaaatcatttgcttcaGCTTGgatt ccgggctgattTTTTATATGATAGTAAAGGAaaaaatgattgagaaaagttgtgatga c" /listShort="S946, trmK, yqfO" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2465121..2465483) /gene="cccA" /locus_tag="BSU_25190" /old_locus_tag="BSU25190" /function="16.7: Manage energy" /function="16.10: Respire" /experiment="publication(s) with functional evidences, PMID:10024472, 10473570, 11361075, 15995641, 19222757" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10024472, 10473570, 11361075, 15995641, 19222757; Product type c: carrier" /codon_start=1 /transl_table=11 /product="cytochrome c550" /protein_id="NP_390398.1" /db_xref="EnsemblGenomes-Gn:BSU25190" /db_xref="EnsemblGenomes-Tr:CAB14449" /db_xref="GOA:P24469" /db_xref="InterPro:IPR009056" /db_xref="InterPro:IPR012218" /db_xref="InterPro:IPR036909" /db_xref="SubtiList:BG10315" /db_xref="UniProtKB/Swiss-Prot:P24469" /translation="MKWNPLIPFLLIAVLGIGLTFFLSVKGLDDSREIASGGESKSAE KKDANASPEEIYKANCIACHGENYEGVSGPSLKGVGDKKDVAEIKTKIEKGGNGMPSG LVPADKLDDMAEWVSKIK*" gene complement(2465121..2465483) /gene="cccA" /locus_tag="BSU_25190" /old_locus_tag="BSU25190" downshifts complement(2465133) /Source="Nicolas_upshifts" /id="D1308" /incds=0 /nref=3 /ntot=88 /MaxReadThrough="4.32389" /MaxDrop="3.4795" /score="-4.13120914" /energy="-7.6" /TU="U1961,U1962" /idTUdmin="U1968" /TUdmin="-7" /isTUend="TRUE" promotor_-35 2465479..2465483 /Source="Nicolas_upshift_promotors" /id="U1960" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp=1 /psig=0 /xcortree=693 /SigmaFactorBS="agcaaaaatggaataagcgggttccatTTCATttcccttCCC CCTTTTTGATCCttccccctatgtaaacacttctaattctaacttatttttacaaaaa g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2465491..2465505 /Source="Nicolas_upshift_promotors" /id="U1960" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp=1 /psig=0 /xcortree=693 /SigmaFactorBS="agcaaaaatggaataagcgggttccatTTCATttcccttCCC CCTTTTTGATCCttccccctatgtaaacacttctaattctaacttatttttacaaaaa g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2465512 /Source="Nicolas_upshifts" /id="U1960" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp=1 /psig=0 /xcortree=693 /SigmaFactorBS="agcaaaaatggaataagcgggttccatTTCATttcccttCCC CCTTTTTGATCCttccccctatgtaaacacttctaattctaacttatttttacaaaaa g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 complement(2465520..2465539) /Source="Nicolas_upshift_promotors" /id="U1961" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.274725274725275" /psig="0.98001998001998" /xcortree=484 /SigmaFactorBS="ataaaaaacttttgtatagcaatcCATTTACTttttgtaaaa aTAAGTTAGAATTAGAAGTGTttacatagggggaaggatcaaaaagggggaagggaaa t" /listShort="cccA, S947, S946, trmK, yqfO" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2465522) /Source="Nicolas_upshifts" /id="U1961" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.274725274725275" /psig="0.98001998001998" /xcortree=484 /SigmaFactorBS="ataaaaaacttttgtatagcaatcCATTTACTttttgtaaaa aTAAGTTAGAATTAGAAGTGTttacatagggggaaggatcaaaaagggggaagggaaa t" /listShort="cccA, S947, S946, trmK, yqfO" /GFF_Attribute="listLong" S_feature complement(2465524..2465645) /Source="Nicolas_S_feature" /locus_tag="new_2599926_2600047_c" /HighExp="Lbstat, T3.0H, T1.30H, M9-stat, T2.30H, T1.0H, T2.0H, T3.30H, M0t90, Lbtran" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigH, SigEF, SigA, SigA, SigA, SigA" /TUshortPSig="0.998, 1, 0.974, 0.979, 1, 1, 0.999" /TUlongSig="SigA, SigGF" /TUlongPSig="0.998, 0.979" /label="S948" promotor_-35 complement(2465551..2465558) /Source="Nicolas_upshift_promotors" /id="U1961" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.274725274725275" /psig="0.98001998001998" /xcortree=484 /SigmaFactorBS="ataaaaaacttttgtatagcaatcCATTTACTttttgtaaaa aTAAGTTAGAATTAGAAGTGTttacatagggggaaggatcaaaaagggggaagggaaa t" /listShort="cccA, S947, S946, trmK, yqfO" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 2465625 /Source="Nicolas_upshift_promotors" /id="U1963" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.485514485514486" /psig="0.997002997002997" /xcortree=360 /SigmaFactorBS="ctttatacaaaattgaatagaaacatgcctaaatctcTaata tcctttttattcTATTGTATAATGTATTGTATacgcttacaatagaaaatatggaatt a" /listShort="S950, S951" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(2465634..2465653) /Source="Nicolas_upshift_promotors" /id="U1962" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.42957042957043" /psig="0.998001998001998" /xcortree=363 /SigmaFactorBS="tgaaaaatttcaaaatctaattccatattttcTATTGTAagc gtatacaataCATTATACAATAGAATAAAAaggatattagagatttaggcatgtttct a" /listShort="S948, cccA, S947, S946, trmK, yqfO" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-10 2465642..2465661 /Source="Nicolas_upshift_promotors" /id="U1963" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.485514485514486" /psig="0.997002997002997" /xcortree=360 /SigmaFactorBS="ctttatacaaaattgaatagaaacatgcctaaatctcTaata tcctttttattcTATTGTATAATGTATTGTATacgcttacaatagaaaatatggaatt a" /listShort="S950, S951" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2465645) /Source="Nicolas_upshifts" /id="U1962" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.42957042957043" /psig="0.998001998001998" /xcortree=363 /SigmaFactorBS="tgaaaaatttcaaaatctaattccatattttcTATTGTAagc gtatacaataCATTATACAATAGAATAAAAaggatattagagatttaggcatgtttct a" /listShort="S948, cccA, S947, S946, trmK, yqfO" /GFF_Attribute="listLong" S_feature complement(2465647..2465786) /Source="Nicolas_S_feature" /locus_tag="new_2600049_2600188_c" /HighExp="Lbstat, S8, S1, S7, G/S, BT, Mal, Gly, S6, Pyr" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigH, SigEF, SigA, SigA, SigA, SigA" /TUshortPSig="1, 0.974, 0.979, 1, 1, 0.999" /TUlongSig="SigA, SigGF" /TUlongPSig="0.998, 0.979" /label="S949" S_feature 2465648..2465752 /Source="Nicolas_S_feature" /locus_tag="new_2600050_2600154" /HighExp="T2.30H, M9-stat, T3.0H, T1.30H, T2.0H, T1.0H, T3.30H, T4.0H, M0t90, T5.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.997" /TUlongSig="NA" /TUlongPSig="NA" /label="S950" upshifts 2465648 /Source="Nicolas_upshifts" /id="U1963" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.485514485514486" /psig="0.997002997002997" /xcortree=360 /SigmaFactorBS="ctttatacaaaattgaatagaaacatgcctaaatctcTaata tcctttttattcTATTGTATAATGTATTGTATacgcttacaatagaaaatatggaatt a" /listShort="S950, S951" /GFF_Attribute="listLong" promotor_-35 complement(2465667..2465673) /Source="Nicolas_upshift_promotors" /id="U1962" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.42957042957043" /psig="0.998001998001998" /xcortree=363 /SigmaFactorBS="tgaaaaatttcaaaatctaattccatattttcTATTGTAagc gtatacaataCATTATACAATAGAATAAAAaggatattagagatttaggcatgtttct a" /listShort="S948, cccA, S947, S946, trmK, yqfO" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 2465716..2465723 /Source="Nicolas_upshift_promotors" /id="U1964" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.955044955044955" /psig=1 /xcortree=558 /SigmaFactorBS="tgaaatttttcaccacaatgttCATTTGCAaatgacatcatt tTTCAGTAAAATAAAGGCATAttatccatatatctttttaaaaaaagaagaacggatc t" /listShort="S951" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2465737..2465756 /Source="Nicolas_upshift_promotors" /id="U1964" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.955044955044955" /psig=1 /xcortree=558 /SigmaFactorBS="tgaaatttttcaccacaatgttCATTTGCAaatgacatcatt tTTCAGTAAAATAAAGGCATAttatccatatatctttttaaaaaaagaagaacggatc t" /listShort="S951" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 2465754..2467903 /Source="Nicolas_S_feature" /locus_tag="new_2600156_2602305" /HighExp="S2, T4.0H, T5.0H, Lbstat, M9-stat, T3.30H, S8, T3.0H, C30, T2.0H" /AntisenseName="sigA" /AntisenseCor="-0.16938350693676901" /AntisenseRegPval="-2.2999999999999998" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="1, 0.997" /TUlongSig="NA" /TUlongPSig="NA" /label="S951" upshifts 2465754 /Source="Nicolas_upshifts" /id="U1964" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.955044955044955" /psig=1 /xcortree=558 /SigmaFactorBS="tgaaatttttcaccacaatgttCATTTGCAaatgacatcatt tTTCAGTAAAATAAAGGCATAttatccatatatctttttaaaaaaagaagaacggatc t" /listShort="S951" /GFF_Attribute="listLong" CDS complement(2465812..2466927) /gene="sigA" /locus_tag="BSU_25200" /old_locus_tag="BSU25200" /function="16.2: Construct biomass (Anabolism)" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:12455702, 12682299, 14527287, 15060039, 15670950, 28648455" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12455702, 12682299, 14527287, 15060039, 15670950, 28648455; Product type f : factor" /codon_start=1 /transl_table=11 /product="RNA polymerase major sigma-43 factor (sigma-A)" /protein_id="NP_390399.2" /db_xref="EnsemblGenomes-Gn:BSU25200" /db_xref="EnsemblGenomes-Tr:CAB14450" /db_xref="GOA:P06224" /db_xref="InterPro:IPR000943" /db_xref="InterPro:IPR007127" /db_xref="InterPro:IPR007624" /db_xref="InterPro:IPR007627" /db_xref="InterPro:IPR007630" /db_xref="InterPro:IPR009042" /db_xref="InterPro:IPR012760" /db_xref="InterPro:IPR013324" /db_xref="InterPro:IPR013325" /db_xref="InterPro:IPR014284" /db_xref="InterPro:IPR028630" /db_xref="InterPro:IPR036388" /db_xref="SubtiList:BG10314" /db_xref="UniProtKB/Swiss-Prot:P06224" /translation="MADKQTHETELTFDQVKEQLTESGKKRGVLTYEEIAERMSSFEI ESDQMDEYYEFLGEQGVELISENEETEDPNIQQLAKAEEEFDLNDLSVPPGVKINDPV RMYLKEIGRVNLLSAKEEIAYAQKIEEGDEESKRRLAEANLRLVVSIAKRYVGRGMLF LDLIQEGNMGLMKAVEKFDYRKGYKFSTYATWWIRQAITRAIADQARTIRIPVHMVET INKLIRVQRQLLQDLGREPTPEEIAEDMDLTPEKVREILKIAQEPVSLETPIGEEDDS HLGDFIEDQEATSPSDHAAYELLKEQLEDVLDTLTDREENVLRLRFGLDDGRTRTLEE VGKVFGVTRERIRQIEAKALRKLRHPSRSKRLKDFLE*" gene complement(2465812..2466927) /gene="sigA" /locus_tag="BSU_25200" /old_locus_tag="BSU25200" downshifts complement(2465831) /Source="Nicolas_upshifts" /id="D1309" /incds=0 /nref=118 /ntot=198 /MaxReadThrough="4.93947" /MaxDrop="6.16048" /score="4.75833607" /energy="-11.7" /TU="U1966,U1968,U1969,U1970,U1972,U1973" /idTUdmin="U1970" /TUdmin="-287" /isTUend="FALSE" S_feature complement(2466928..2467125) /Source="Nicolas_S_feature" /locus_tag="new_2601330_2601527_c" /HighExp="BC, Cold, SMMPr, S1, BI, G135, C30, Lbstat, S5, C90" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigH, SigEF, SigA, SigA, SigA, SigA" /TUshortPSig="1, 0.974, 0.979, 1, 1, 0.999" /TUlongSig="SigA, SigGF" /TUlongPSig="0.998, 0.979" /label="S952" CDS complement(2467126..2468937) /gene="dnaG" /locus_tag="BSU_25210" /old_locus_tag="BSU25210" /EC_number="2.7.7.-" /function="16.9: Replicate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 3100394, 9387153, 12682299, 16036556, 28386108; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="DNA primase" /protein_id="NP_390400.2" /db_xref="EnsemblGenomes-Gn:BSU25210" /db_xref="EnsemblGenomes-Tr:CAB14451" /db_xref="GOA:P05096" /db_xref="InterPro:IPR002694" /db_xref="InterPro:IPR006171" /db_xref="InterPro:IPR006295" /db_xref="InterPro:IPR013264" /db_xref="InterPro:IPR016136" /db_xref="InterPro:IPR019475" /db_xref="InterPro:IPR030846" /db_xref="InterPro:IPR034151" /db_xref="InterPro:IPR036185" /db_xref="InterPro:IPR036977" /db_xref="InterPro:IPR037068" /db_xref="PDB:5GUJ" /db_xref="SubtiList:BG10313" /db_xref="UniProtKB/Swiss-Prot:P05096" /translation="MGNRIPDEIVDQVQKSADIVEVIGDYVQLKKQGRNYFGLCPFHG ESTPSFSVSPDKQIFHCFGCGAGGNVFSFLRQMEGYSFAESVSHLADKYQIDFPDDIT VHSGARPESSGEQKMAEAHELLKKFYHHLLINTKEGQEALDYLLSRGFTKELINEFQI GYALDSWDFITKFLVKRGFSEAQMEKAGLLIRREDGSGYFDRFRNRVMFPIHDHHGAV VAFSGRALGSQQPKYMNSPETPLFHKSKLLYNFYKARLHIRKQERAVLFEGFADVISA VSSDVKESIATMGTSLTDDHVKILRRNVEEIILCYDSDKAGYEATLKASELLQKKGCK VRVAMIPDGLDPDDYIKKFGGEKFKNDIIDASVTVMAFKMQYFRKGKNLSDEGDRLAY IKDVLKEISTLSGSLEQEVYVKQLASEFSLSQESLTEQLSVFSKQNKPADNSGETKTR RAHLTTKARQKRLRPAYENAERLLLAHMLRDRSVIKKVIDRVGFQFNIDEHRALAAYL YAFYEEGAELTPQHLMARVTDDHISQLLSDILMLQVNQELSEAELSDYVKKVLNQRNW SMIKEKEAERAEAERQKDFLRAASLAQEIVTLNRSLK*" gene complement(2467126..2468937) /gene="dnaG" /locus_tag="BSU_25210" /old_locus_tag="BSU25210" promotor_-35 2468532..2468538 /Source="Nicolas_upshift_promotors" /id="U1965" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.738261738261738" /psig="0.998001998001998" /xcortree=455 /SigmaFactorBS="aaagcccctagaaagcagataatccagtgcctcttgaccttc ttTTGTATTtattaacaaatGATGGTAAAATTTCTTCAGGagctcatgtgcctcagcc a" /listShort="antE" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 2468548 /Source="Nicolas_upshifts" /id="U1965" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.738261738261738" /psig="0.998001998001998" /xcortree=455 /SigmaFactorBS="aaagcccctagaaagcagataatccagtgcctcttgaccttc ttTTGTATTtattaacaaatGATGGTAAAATTTCTTCAGGagctcatgtgcctcagcc a" /listShort="antE" /GFF_Attribute="listLong" promotor_-10 2468550..2468569 /Source="Nicolas_upshift_promotors" /id="U1965" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.738261738261738" /psig="0.998001998001998" /xcortree=455 /SigmaFactorBS="aaagcccctagaaagcagataatccagtgcctcttgaccttc ttTTGTATTtattaacaaatGATGGTAAAATTTCTTCAGGagctcatgtgcctcagcc a" /listShort="antE" /GFF_Attribute="listLong" /label="promotor_-10" CDS 2468577..2468873 /gene="antE" /locus_tag="BSU_25220" /old_locus_tag="BSU25220" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function; PubMedId: 9864351" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_054587.1" /db_xref="EnsemblGenomes-Gn:BSU25220" /db_xref="EnsemblGenomes-Tr:CAE01462" /db_xref="GOA:Q7WY63" /db_xref="SubtiList:BG14178" /db_xref="UniProtKB/Swiss-Prot:Q7WY63" /translation="MPQPFFVLQKTLAGLRNGLLYHLENQFGICQQGEKPTRQKNSLP SALKKRKHCRPLRSQSNEKSVCRAIRKTKVCFLHEKDRVQSSFGLASLIEHNHL*" gene 2468577..2468873 /gene="antE" /locus_tag="BSU_25220" /old_locus_tag="BSU25220" CDS complement(2468971..2469465) /gene="yqxD" /locus_tag="BSU_25230" /old_locus_tag="BSU25230" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 9387153, 22720735" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_390401.2" /db_xref="EnsemblGenomes-Gn:BSU25230" /db_xref="EnsemblGenomes-Tr:CAB14452" /db_xref="InterPro:IPR003791" /db_xref="SubtiList:BG10312" /db_xref="UniProtKB/Swiss-Prot:P17868" /translation="MEGWRITLLNEQEKTIFVDADACPVKDEILQTASEYEVQVLFVA SFEHYQLSRSNEEKWKYVDPHKEAADLYIANHVKPGDIVVTQDIGLASLLLNRNVSVM SERGRLYKEDTIDFALEGRHFSGKQRRKGVYAKGPKKLNKEDRERFITLLQKILSNDE GILH*" gene complement(2468971..2469465) /gene="yqxD" /locus_tag="BSU_25230" /old_locus_tag="BSU25230" promotor_-10 complement(2469438..2469456) /Source="Nicolas_upshift_promotors" /id="U1966" /multdbtbs="SigH" /comp="M1" /sig="SigH" /pcomp=1 /psig=1 /xcortree=431 /SigmaFactorBS="taataaaggatgtgcgattttgcttgcttttatGCAGGAGTT taatggagggaTGGAGAATTACTCTTCTTAatgaacaagaaaagacgatttttgtcga t" /listShort="yqxD, dnaG, S952, sigA, S949, S948, cccA" /listLong="S947, S946, trmK, yqfO" /label="promotor_-10" upshifts complement(2469449) /Source="Nicolas_upshifts" /id="U1966" /multdbtbs="SigH" /comp="M1" /sig="SigH" /pcomp=1 /psig=1 /xcortree=431 /SigmaFactorBS="taataaaggatgtgcgattttgcttgcttttatGCAGGAGTT taatggagggaTGGAGAATTACTCTTCTTAatgaacaagaaaagacgatttttgtcga t" /listShort="yqxD, dnaG, S952, sigA, S949, S948, cccA" /listLong="S947, S946, trmK, yqfO" S_feature complement(2469466..2469579) /Source="Nicolas_S_feature" /locus_tag="new_2603868_2603981_c" /HighExp="S5, S4, S6, S7, S8, S3, Etha, dia15, G180, G150" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigEF, SigA, SigA, SigA, SigA" /TUshortPSig="0.974, 0.979, 1, 1, 0.999" /TUlongSig="SigA, SigGF" /TUlongPSig="0.998, 0.979" /label="S953" promotor_-35 complement(2469468..2469476) /Source="Nicolas_upshift_promotors" /id="U1966" /multdbtbs="SigH" /comp="M1" /sig="SigH" /pcomp=1 /psig=1 /xcortree=431 /SigmaFactorBS="taataaaggatgtgcgattttgcttgcttttatGCAGGAGTT taatggagggaTGGAGAATTACTCTTCTTAatgaacaagaaaagacgatttttgtcga t" /listShort="yqxD, dnaG, S952, sigA, S949, S948, cccA" /listLong="S947, S946, trmK, yqfO" /label="promotor_-35" promotor_-35 2469474..2469479 /Source="Nicolas_upshift_promotors" /id="U1967" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.832167832167832" /psig="0.832167832167832" /xcortree=1219 /SigmaFactorBS="ttctccatccctccattaaactccTGCATAaaagcaagcaaa atcGCACATCCTTTATTATTGTggatgtatatgaatttgtcgaaaaatttccgggaga a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2469495..2469513 /Source="Nicolas_upshift_promotors" /id="U1967" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.832167832167832" /psig="0.832167832167832" /xcortree=1219 /SigmaFactorBS="ttctccatccctccattaaactccTGCATAaaagcaagcaaa atcGCACATCCTTTATTATTGTggatgtatatgaatttgtcgaaaaatttccgggaga a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2469510 /Source="Nicolas_upshifts" /id="U1967" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.832167832167832" /psig="0.832167832167832" /xcortree=1219 /SigmaFactorBS="ttctccatccctccattaaactccTGCATAaaagcaagcaaa atcGCACATCCTTTATTATTGTggatgtatatgaatttgtcgaaaaatttccgggaga a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 complement(2469564..2469582) /Source="Nicolas_upshift_promotors" /id="U1968" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.974025974025974" /psig="0.974025974025974" /xcortree=794 /SigmaFactorBS="ttataataaaaaattgtgataaaatgattaattttaGGTTTA aggatcgtgtgatacGAATAAACTATTATGGGTAagatgtcaagaatttctcccggaa a" /listShort="S953, yqxD, dnaG, S952, sigA, S949, S948, cccA" /listLong="S947, S946, trmK, yqfO" /label="promotor_-10" upshifts complement(2469579) /Source="Nicolas_upshifts" /id="U1968" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.974025974025974" /psig="0.974025974025974" /xcortree=794 /SigmaFactorBS="ttataataaaaaattgtgataaaatgattaattttaGGTTTA aggatcgtgtgatacGAATAAACTATTATGGGTAagatgtcaagaatttctcccggaa a" /listShort="S953, yqxD, dnaG, S952, sigA, S949, S948, cccA" /listLong="S947, S946, trmK, yqfO" S_feature complement(2469581..2469658) /Source="Nicolas_S_feature" /locus_tag="new_2603983_2604060_c" /HighExp="Etha, G180, G135, G150, LBGtran, LBGexp, dia15, H2O2, Oxctl, Salt" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA, SigA, SigA" /TUshortPSig="0.979, 1, 1, 0.999" /TUlongSig="SigA, SigGF" /TUlongPSig="0.998, 0.979" /label="S954" promotor_-35 complement(2469598..2469603) /Source="Nicolas_upshift_promotors" /id="U1968" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.974025974025974" /psig="0.974025974025974" /xcortree=794 /SigmaFactorBS="ttataataaaaaattgtgataaaatgattaattttaGGTTTA aggatcgtgtgatacGAATAAACTATTATGGGTAagatgtcaagaatttctcccggaa a" /listShort="S953, yqxD, dnaG, S952, sigA, S949, S948, cccA" /listLong="S947, S946, trmK, yqfO" /label="promotor_-35" promotor_-10 complement(2469624..2469643) /Source="Nicolas_upshift_promotors" /id="U1969" /multdbtbs="SigA,SigA" /comp="M16" /sig="SigA" /pcomp="0.731268731268731" /psig="0.97902097902098" /xcortree=2530 /SigmaFactorBS="ctcaggacgctctatcctgggtttttggctgtgccaaaaggg aataatgaaaaacaATAGcatctttgtgaagttTGTATTATAATAAAAAATTGtgata a" /listShort="S954, S953, yqxD, dnaG, S952, sigA, S949, S948, cccA" /listLong="S947, S946, trmK, yqfO" /label="promotor_-10" upshifts complement(2469658) /Source="Nicolas_upshifts" /id="U1969" /multdbtbs="SigA,SigA" /comp="M16" /sig="SigA" /pcomp="0.731268731268731" /psig="0.97902097902098" /xcortree=2530 /SigmaFactorBS="ctcaggacgctctatcctgggtttttggctgtgccaaaaggg aataatgaaaaacaATAGcatctttgtgaagttTGTATTATAATAAAAAATTGtgata a" /listShort="S954, S953, yqxD, dnaG, S952, sigA, S949, S948, cccA" /listLong="S947, S946, trmK, yqfO" promotor_-35 complement(2469659..2469662) /Source="Nicolas_upshift_promotors" /id="U1969" /multdbtbs="SigA,SigA" /comp="M16" /sig="SigA" /pcomp="0.731268731268731" /psig="0.97902097902098" /xcortree=2530 /SigmaFactorBS="ctcaggacgctctatcctgggtttttggctgtgccaaaaggg aataatgaaaaacaATAGcatctttgtgaagttTGTATTATAATAAAAAATTGtgata a" /listShort="S954, S953, yqxD, dnaG, S952, sigA, S949, S948, cccA" /listLong="S947, S946, trmK, yqfO" /label="promotor_-35" CDS complement(2469719..2470531) /gene="ppsR" /locus_tag="BSU_25240" /old_locus_tag="BSU25240" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:15720552, 20044937" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15720552, 20044937; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="bifunctional ADP-dependent kinase-Pi-dependent pyrophosphorylase / positive regulator of gluconeogenesis" /protein_id="NP_390402.1" /db_xref="EnsemblGenomes-Gn:BSU25240" /db_xref="EnsemblGenomes-Tr:CAB14453" /db_xref="GOA:P54470" /db_xref="InterPro:IPR005177" /db_xref="InterPro:IPR026565" /db_xref="SubtiList:BG11659" /db_xref="UniProtKB/Swiss-Prot:P54470" /translation="MNNRIIYVVSDSVGETAELVVKAALSQFNGSADDTHVRRIPYVE DIGTINEVISLAKADGGIICFTLVVPEIREYLIAEAEKANVLYYDIIGPLIDKMETAY GLTAKYEPGRVRQLDEDYFKKVEAIEFAVKYDDGRDPRGILKADIVLIGVSRTSKTPL SQYLAHKRLKVANVPIVPEVDPPEELFNVDPKKCIGLKISPDKLNHIRKERLKSLGLN DKAIYANINRIKEELEYFEKIVDRIGCQVVDVSNKAVEETANIIHHLKTKNI*" gene complement(2469719..2470531) /gene="ppsR" /locus_tag="BSU_25240" /old_locus_tag="BSU25240" CDS complement(2470557..2471195) /gene="ccpN" /locus_tag="BSU_25250" /old_locus_tag="BSU25250" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:15720552, 17011578, 17962296, 18511073, 18586936, 19202299, 19726675, 28178965" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15720552, 17011578, 17962296, 18511073, 18586936, 19202299, 19726675, 28178965; Product type r: regulator" /codon_start=1 /transl_table=11 /product="negative regulator of gluconeogenesis" /protein_id="NP_390403.1" /db_xref="EnsemblGenomes-Gn:BSU25250" /db_xref="EnsemblGenomes-Tr:CAB14454" /db_xref="GOA:O34994" /db_xref="InterPro:IPR000644" /db_xref="InterPro:IPR013196" /db_xref="InterPro:IPR016842" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="PDB:3FV6" /db_xref="PDB:3FWR" /db_xref="PDB:3FWS" /db_xref="SubtiList:BG13768" /db_xref="UniProtKB/Swiss-Prot:O34994" /translation="MSTIELNKRQEHILQIVKENGPITGEHIAEKLNLTRATLRPDLA ILTMSGFLEARPRVGYFYTGKTGTQLLADKLKKLQVKDFQSIPVVIHENVSVYDAICT MFLEDVGTLFVVDRDAVLVGVLSRKDLLRASIGQQELTSVPVHIIMTRMPNITVCRRE DYVMDIAKHLIEKQIDALPVIKDTDKGFEVIGRVTKTNMTKILVSLSENEIL*" gene complement(2470557..2471195) /gene="ccpN" /locus_tag="BSU_25250" /old_locus_tag="BSU25250" S_feature complement(2471196..2471327) /Source="Nicolas_S_feature" /locus_tag="new_2605598_2605729_c" /HighExp="G135, dia5, G180, G150, dia15, H2O2, LBGexp, Lbexp, Oxctl, Paraq" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA, SigA, SigA" /TUshortPSig="1, 1, 0.999, 0.998" /TUlongSig="SigGF" /TUlongPSig="0.979" /label="S955" promotor_-10 complement(2471321..2471340) /Source="Nicolas_upshift_promotors" /id="U1970" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.955044955044955" /psig=1 /xcortree=2057 /SigmaFactorBS="atggtaagcttggcggatgagatcaagtCCTTTGCGaatatg aatgccctTATTGTAAAATAAAGAGAGAaaaggcggttgctgtgtgatcggtaatcgt c" /listShort="S955, ccpN, yqfL, S954, S953, yqxD, dnaG, S952, sigA, S949, S948" /listLong="cccA, S947, S946, trmK, yqfO" /label="promotor_-10" CDS complement(2471328..2473367) /gene="glyS" /locus_tag="BSU_25260" /old_locus_tag="BSU25260" /EC_number="6.1.1.14" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 12682299, 15890195; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="glycyl-tRNA synthetase (beta subunit)" /protein_id="NP_390404.2" /db_xref="EnsemblGenomes-Gn:BSU25260" /db_xref="EnsemblGenomes-Tr:CAB14455" /db_xref="GOA:P54381" /db_xref="InterPro:IPR006194" /db_xref="InterPro:IPR009080" /db_xref="InterPro:IPR015944" /db_xref="SubtiList:BG11658" /db_xref="UniProtKB/Swiss-Prot:P54381" /translation="MSKQDLLLEIGLEEMPARFLNESMVQLGDKLTGWLKEKNITHGE VKLFNTPRRLAVFVKDVAEKQDDIKEEAKGPAKKIALDADGNWTKAAIGFSKGQGANV EDLYIKEVKGIEYVFVQKFQAGQETKSLLPELSGLITSLHFPKNMRWGNEDLRYIRPI KWIVALFGQDVIPFSITNVESGRTTQGHRFLGHEVSIESPSAYEEQLKGQHVIADPSV RKQMIQSQLETMAAENNWSIPVDEDLLDEVNHLVEYPTALYGSFESEFLSIPEEVLVT TMKEHQRYFPVKDKNGDLLPHFITVRNGNSHAIENVARGNEKVLRARLSDASFFYKED QKLNIDANVKKLENIVFHEELGSLADKVRRVTSIAEKLAVRLQADEDTLKHVKRAAEI SKFDLVTHMIYEFPELQGIMGEKYARMLGEDEAVAAAVNEHYMPRSAGGETPSTFTGA VVAMADKLDTIASFFSIGVIPTGSQDPYGLRRQASGIVAILLDRNWGISFEELLTFVQ TDKENELLDFFTQRLKYVLNAEQIRHDVIDAVLESSELEPYSALHKAQVLEQKLGAPG FKETAEALGRVISISKKGVRGDIQPDLFENEYEAKLFDAYQTAKQNLQENFSKKDYEA ALASLAALKEPIDAYFDHTMVIADNESLKANRLAQMVSLADEIKSFANMNALIVK*" gene complement(2471328..2473367) /gene="glyS" /locus_tag="BSU_25260" /old_locus_tag="BSU25260" upshifts complement(2471330) /Source="Nicolas_upshifts" /id="U1970" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.955044955044955" /psig=1 /xcortree=2057 /SigmaFactorBS="atggtaagcttggcggatgagatcaagtCCTTTGCGaatatg aatgccctTATTGTAAAATAAAGAGAGAaaaggcggttgctgtgtgatcggtaatcgt c" /listShort="S955, ccpN, yqfL, S954, S953, yqxD, dnaG, S952, sigA, S949, S948" /listLong="cccA, S947, S946, trmK, yqfO" promotor_-35 complement(2471355..2471362) /Source="Nicolas_upshift_promotors" /id="U1970" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.955044955044955" /psig=1 /xcortree=2057 /SigmaFactorBS="atggtaagcttggcggatgagatcaagtCCTTTGCGaatatg aatgccctTATTGTAAAATAAAGAGAGAaaaggcggttgctgtgtgatcggtaatcgt c" /listShort="S955, ccpN, yqfL, S954, S953, yqxD, dnaG, S952, sigA, S949, S948" /listLong="cccA, S947, S946, trmK, yqfO" /label="promotor_-35" downshifts complement(2471374) /Source="Nicolas_upshifts" /id="D1310" /incds=0 /nref=1 /ntot=2 /MaxReadThrough="6.14024" /MaxDrop="3.62589" /score="-9.01330408" /energy="-8.2" /TU="U1972,U1973,U1975" /idTUdmin="U1975" /TUdmin="-1320" /isTUend="FALSE" downshifts complement(2471440) /Source="Nicolas_upshifts" /id="D1311" /incds=1 /nref=10 /ntot=162 /MaxReadThrough="6.17154" /MaxDrop="3.30313" /score="-9.01330408" /energy="-8.2" /TU="U1972,U1973,U1975" /idTUdmin="U1975" /TUdmin="-1386" /isTUend="FALSE" CDS complement(2473360..2474247) /gene="glyQ" /locus_tag="BSU_25270" /old_locus_tag="BSU25270" /EC_number="6.1.1.14" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 12682299, 15890195; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="glycyl-tRNA synthetase (alpha subunit)" /protein_id="NP_390405.1" /db_xref="EnsemblGenomes-Gn:BSU25270" /db_xref="EnsemblGenomes-Tr:CAB14456" /db_xref="GOA:P54380" /db_xref="InterPro:IPR002310" /db_xref="InterPro:IPR006194" /db_xref="SubtiList:BG11657" /db_xref="UniProtKB/Swiss-Prot:P54380" /translation="MNIQDMILTLQKHWSSQGCVLMQAYDVEKGAGTMSPYTFLRSIG PEPWKVAYVEPSRRPADGRYGENPNRLYQHHQFQVIIKPSPDNIQELYLDSLRALGID PLEHDIRFVEDNWENPSLGCAGLGWEVWLDGMEITQFTYFQQVGGLECKPVSVEITYG IERLASYIQDKENVFDLEWTSGFTVKDLFMMAEYEHSVYTFETSDVDMLFQLFSTYEK EAIKQMDNGLVHPAYDYVLKCSHTFNLLDAKGAISVTERTGYIARVRNLARKVAKTYY EEREKLGFPMLKGEGSSHE*" gene complement(2473360..2474247) /gene="glyQ" /locus_tag="BSU_25270" /old_locus_tag="BSU25270" misc_RNA complement(2474330..2474504) /gene="tboG" /locus_tag="BSU_misc_RNA_39" /product="T-box riboswitch controlling synthesis of glycine-tRNA ligase" /experiment="publication(s) with functional evidences, PMID:1317842, 9098041, 12165569, 12547201, 15890195, 26229106" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1317842, 9098041, 12165569, 12547201, 15890195, 26229106; Product type n : RNA" gene complement(2474330..2474504) /gene="tboG" /locus_tag="BSU_misc_RNA_39" downshifts complement(2474364) /Source="Nicolas_upshifts" /id="D1312" /incds=0 /nref=70 /ntot=220 /MaxReadThrough="6.60948" /MaxDrop="5.42847" /score="18.9025126" /energy="-23.3" /TU="U1972,U1973,U1975" /idTUdmin="U1976" /TUdmin=178 /isTUend="FALSE" promotor_-35 2474479..2474484 /Source="Nicolas_upshift_promotors" /id="U1971" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.955044955044955" /psig="0.955044955044955" /xcortree=959 /SigmaFactorBS="ctaaggtcgctttcatgaggtaaacgcaaGTACTTctttctc tcactgcaACATATTTTATAATAAATGatcatataaaaagatggaccaaatgtcaact t" /listShort="S956" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2474500..2474518 /Source="Nicolas_upshift_promotors" /id="U1971" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.955044955044955" /psig="0.955044955044955" /xcortree=959 /SigmaFactorBS="ctaaggtcgctttcatgaggtaaacgcaaGTACTTctttctc tcactgcaACATATTTTATAATAAATGatcatataaaaagatggaccaaatgtcaact t" /listShort="S956" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-10 complement(2474508..2474527) /Source="Nicolas_upshift_promotors" /id="U1972" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.911088911088911" /psig=1 /xcortree=3007 /SigmaFactorBS="aagcatgaaacatcttatgggtgaaaacaaaAGTTGACAttt ggtccatctttTTATATGATCATTTATTATAaaatatgttgcagtgagagaaagaagt a" /listShort="NA, glyQ, glyS, S955, ccpN, yqfL, S954, S953, yqxD, dnaG, S952, sigA, S949, S948, cccA" /listLong="S947, S946, trmK, yqfO" /label="promotor_-10" S_feature 2474510..2475922 /Source="Nicolas_S_feature" /locus_tag="new_2608912_2610324" /HighExp="C30, S8, Gly, BT, G135, Fru, S6, C90, Lbstat, Mal" /AntisenseName="recO" /AntisenseCor="0.22892689952134901" /AntisenseRegPval="-3.8" /CDS_PredictionProba="NA" /TUshortSig="SigEF" /TUshortPSig="0.955" /TUlongSig="NA" /TUlongPSig="NA" /label="S956" upshifts 2474510 /Source="Nicolas_upshifts" /id="U1971" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.955044955044955" /psig="0.955044955044955" /xcortree=959 /SigmaFactorBS="ctaaggtcgctttcatgaggtaaacgcaaGTACTTctttctc tcactgcaACATATTTTATAATAAATGatcatataaaaagatggaccaaatgtcaact t" /listShort="S956" /GFF_Attribute="listLong" upshifts complement(2474520) /Source="Nicolas_upshifts" /id="U1972" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.911088911088911" /psig=1 /xcortree=3007 /SigmaFactorBS="aagcatgaaacatcttatgggtgaaaacaaaAGTTGACAttt ggtccatctttTTATATGATCATTTATTATAaaatatgttgcagtgagagaaagaagt a" /listShort="NA, glyQ, glyS, S955, ccpN, yqfL, S954, S953, yqxD, dnaG, S952, sigA, S949, S948, cccA" /listLong="S947, S946, trmK, yqfO" promotor_-35 complement(2474542..2474549) /Source="Nicolas_upshift_promotors" /id="U1972" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.911088911088911" /psig=1 /xcortree=3007 /SigmaFactorBS="aagcatgaaacatcttatgggtgaaaacaaaAGTTGACAttt ggtccatctttTTATATGATCATTTATTATAaaatatgttgcagtgagagaaagaagt a" /listShort="NA, glyQ, glyS, S955, ccpN, yqfL, S954, S953, yqxD, dnaG, S952, sigA, S949, S948, cccA" /listLong="S947, S946, trmK, yqfO" /label="promotor_-35" CDS complement(2474544..2475311) /gene="recO" /locus_tag="BSU_25280" /old_locus_tag="BSU25280" /function="16.9: Replicate" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:10323239, 15186413, 16061691, 26001966" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10323239, 15186413, 16061691, 26001966; Product type f: factor" /codon_start=1 /transl_table=11 /product="DNA double strand break repair and homologous recombination factor" /protein_id="NP_390406.2" /db_xref="EnsemblGenomes-Gn:BSU25280" /db_xref="EnsemblGenomes-Tr:CAB14457" /db_xref="GOA:P42095" /db_xref="InterPro:IPR003717" /db_xref="InterPro:IPR012340" /db_xref="InterPro:IPR022572" /db_xref="SubtiList:BG11189" /db_xref="UniProtKB/Swiss-Prot:P42095" /translation="MLTKCEGIVLRTNDYGETNKIVTLLTREHGKIGVMARGAKKPNS RLSAVSQPFLYGSFLMQKTSGLGTLQQGEMILSMRGIREDLFLTAYAAYVAELVDRGT EEKKPNPYLFEFILESLKQLNEGTDPDVITFIVQMKMLGVMGLYPELNHCVHCKSQDG TFHFSVRDNGFICHRCFEKDPYRIPIKPQTARLLRLFYYFDLSRLGNVSLKEETKAEL KQVIDLYYEEYSGLYLKSKRFLDQMESMKHLMGENKS*" gene complement(2474544..2475311) /gene="recO" /locus_tag="BSU_25280" /old_locus_tag="BSU25280" CDS complement(2475348..2475491) /gene="yqzL" /locus_tag="BSU_25289" /old_locus_tag="BSU25289" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="YP_003097761.1" /db_xref="EnsemblGenomes-Gn:BSU25289" /db_xref="EnsemblGenomes-Tr:CAX52661" /db_xref="InterPro:IPR025617" /db_xref="UniProtKB/Swiss-Prot:C0H452" /translation="MLNFTWNVFSQTGNVDTYLLFKELEKENMERPEELEDELARFDY PIL*" gene complement(2475348..2475491) /gene="yqzL" /locus_tag="BSU_25289" /old_locus_tag="BSU25289" S_feature complement(2475492..2475638) /Source="Nicolas_S_feature" /locus_tag="new_2609894_2610040_c" /HighExp="Lbstat, T1.30H, T2.0H, M9-stat, S2, T3.0H, S5, M0t90, T2.30H, T4.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA, SigB" /TUshortPSig="0.999, 0.998, 1" /TUlongSig="SigGF" /TUlongPSig="0.979" /label="S957" CDS complement(2475639..2476544) /gene="era" /locus_tag="BSU_25290" /old_locus_tag="BSU25290" /function="16.13: Shape" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:12399511, 12427945, 12682299, 21646538, 22720735, 27834201, 28132488" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12399511, 12427945, 12682299, 21646538, 22720735, 27834201, 28132488; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="maturation of 16S RNA and assembly of 30S ribosomal subunit GTPase" /protein_id="NP_390407.1" /db_xref="EnsemblGenomes-Gn:BSU25290" /db_xref="EnsemblGenomes-Tr:CAB14458" /db_xref="GOA:P42182" /db_xref="InterPro:IPR004044" /db_xref="InterPro:IPR005225" /db_xref="InterPro:IPR005662" /db_xref="InterPro:IPR006073" /db_xref="InterPro:IPR009019" /db_xref="InterPro:IPR015946" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR030388" /db_xref="SubtiList:BG11188" /db_xref="UniProtKB/Swiss-Prot:P42182" /translation="MTNESFKSGFVSIIGRPNVGKSTFLNRVIGQKIAIMSDKPQTTR NKVQGVLTTGTSQTIFIDTPGIHKPKHKLGDFMMKVAQNTLKEVDLILFMINAEEGYG KGDEFIIEKLQTMSTPVFLIVNKIDKIHPDQLLLLIDEYRKRYPFKEIVPISALEGNN IETLLAQIEAYLPEGPQFYPSDQVTDHPERFIISELIREKVLHLTREEIPHSIAVAIE SIKGQDNGSVHVAATIVVERDSQKGIVIGKKGSLLKEVGKRARADIEALLGSRVYLEL WVKVQKDWRNKMSQLRDFGFKEDEY*" gene complement(2475639..2476544) /gene="era" /locus_tag="BSU_25290" /old_locus_tag="BSU25290" CDS complement(2476525..2476935) /gene="cdd" /locus_tag="BSU_25300" /old_locus_tag="BSU25300" /EC_number="3.5.4.5" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:2526291, 8157589, 10217788, 11851403, 22720735, 25890046" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 2526291, 8157589, 10217788, 11851403, 22720735, 25890046; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="cytidine/deoxycytidine deaminase" /protein_id="NP_390408.1" /db_xref="EnsemblGenomes-Gn:BSU25300" /db_xref="EnsemblGenomes-Tr:CAB14459" /db_xref="GOA:P19079" /db_xref="InterPro:IPR002125" /db_xref="InterPro:IPR006262" /db_xref="InterPro:IPR016192" /db_xref="InterPro:IPR016193" /db_xref="PDB:1JTK" /db_xref="PDB:1UWZ" /db_xref="PDB:1UX0" /db_xref="PDB:1UX1" /db_xref="SubtiList:BG10477" /db_xref="UniProtKB/Swiss-Prot:P19079" /translation="MNRQELITEALKARDMAYAPYSKFQVGAALLTKDGKVYRGCNIE NAAYSMCNCAERTALFKAVSEGDTEFQMLAVAADTPGPVSPCGACRQVISELCTKDVI VVLTNLQGQIKEMTVEELLPGAFSSEDLHDERKL*" gene complement(2476525..2476935) /gene="cdd" /locus_tag="BSU_25300" /old_locus_tag="BSU25300" promotor_-10 complement(2476973..2476992) /Source="Nicolas_upshift_promotors" /id="U1973" /multdbtbs="SigA,SigB" /comp="M7" /sig="SigA" /pcomp="0.873126873126873" /psig="0.999000999001" /xcortree=528 /SigmaFactorBS="attcttacatttattttacatttttagaaatgggCGTGaaaa aaagcgcgcgATTATGTAAAATATAAAGTGatagcggtaccattataggtaagagagg a" /listShort="cdd, era, S957, yqzL, recO, NA, glyQ, glyS, S955, ccpN, yqfL, S954, S953, yqxD, dnaG, S952, sigA, S949, S948" /listLong="cccA, S947, S946, trmK, yqfO" /label="promotor_-10" upshifts complement(2476984) /Source="Nicolas_upshifts" /id="U1973" /multdbtbs="SigA,SigB" /comp="M7" /sig="SigA" /pcomp="0.873126873126873" /psig="0.999000999001" /xcortree=528 /SigmaFactorBS="attcttacatttattttacatttttagaaatgggCGTGaaaa aaagcgcgcgATTATGTAAAATATAAAGTGatagcggtaccattataggtaagagagg a" /listShort="cdd, era, S957, yqzL, recO, NA, glyQ, glyS, S955, ccpN, yqfL, S954, S953, yqxD, dnaG, S952, sigA, S949, S948" /listLong="cccA, S947, S946, trmK, yqfO" S_feature complement(2476986..2477053) /Source="Nicolas_S_feature" /locus_tag="new_2611388_2611455_c" /HighExp="Oxctl, H2O2, G180, G150, GM 120, S1, G135, Diami, LBGtran, C30" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigB" /TUshortPSig="0.998, 1" /TUlongSig="SigGF" /TUlongPSig="0.979" /label="S958" promotor_-35 complement(2477007..2477010) /Source="Nicolas_upshift_promotors" /id="U1973" /multdbtbs="SigA,SigB" /comp="M7" /sig="SigA" /pcomp="0.873126873126873" /psig="0.999000999001" /xcortree=528 /SigmaFactorBS="attcttacatttattttacatttttagaaatgggCGTGaaaa aaagcgcgcgATTATGTAAAATATAAAGTGatagcggtaccattataggtaagagagg a" /listShort="cdd, era, S957, yqzL, recO, NA, glyQ, glyS, S955, ccpN, yqfL, S954, S953, yqxD, dnaG, S952, sigA, S949, S948" /listLong="cccA, S947, S946, trmK, yqfO" /label="promotor_-35" CDS complement(2477054..2477425) /gene="unpK" /locus_tag="BSU_25310" /old_locus_tag="BSU25310" /EC_number="2.7.1.66" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 12923107, 17535816, 19935659, 28872301; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="undecaprenol kinase" /protein_id="NP_390409.2" /db_xref="EnsemblGenomes-Gn:BSU25310" /db_xref="EnsemblGenomes-Tr:CAB14460" /db_xref="GOA:P19638" /db_xref="InterPro:IPR000829" /db_xref="InterPro:IPR033717" /db_xref="InterPro:IPR036945" /db_xref="SubtiList:BG11040" /db_xref="UniProtKB/Swiss-Prot:P19638" /translation="MDSKDHRNELNRFFKSFVHAGRGIWETARTERNFQFHAAAACAV LICGFLVELSIIEWMIIFLLIGGMFSLELLNTAIEHTVDLITDKHHPLAKAAKDAAAG AVCVFAVISCIIGLLIFLPKL*" gene complement(2477054..2477425) /gene="unpK" /locus_tag="BSU_25310" /old_locus_tag="BSU25310" CDS complement(2477406..2477879) /gene="rnrY" /locus_tag="BSU_25320" /old_locus_tag="BSU25320" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 16511207, 16818608, 19181801, 20639334, 20807199, 23273979, 23638028, 24511998, 24901994, 28031281; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="endonuclease involved in 70S ribosomes quality control" /protein_id="NP_390410.2" /db_xref="EnsemblGenomes-Gn:BSU25320" /db_xref="EnsemblGenomes-Tr:CAB14461" /db_xref="GOA:P46347" /db_xref="InterPro:IPR002036" /db_xref="InterPro:IPR020549" /db_xref="InterPro:IPR023091" /db_xref="SubtiList:BG11656" /db_xref="UniProtKB/Swiss-Prot:P46347" /translation="MSLLIDIVDETGSVSEEMLKEVENLLQFAAEREGVQDQAEVSVT IVSNDDIHQINKEYRGKDAPTDVISFALEEEGEGEIEIVGAEMPPVLGDIIISADRTR EQAEEYNHSFKRELGFLAVHGFLHLLGYDHMTKEEEEEMFTKQKELLDAYGLKRS*" gene complement(2477406..2477879) /gene="rnrY" /locus_tag="BSU_25320" /old_locus_tag="BSU25320" CDS complement(2477880..2480015) /gene="pgpH" /locus_tag="BSU_25330" /old_locus_tag="BSU25330" /function="16.3: Control" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:16751502, 26240071, 27378384" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16751502, 26240071, 27378384; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="c-di-AMP-degrading phosphodiesterases" /protein_id="NP_390411.1" /db_xref="EnsemblGenomes-Gn:BSU25330" /db_xref="EnsemblGenomes-Tr:CAB14462" /db_xref="GOA:P46344" /db_xref="InterPro:IPR003607" /db_xref="InterPro:IPR006674" /db_xref="InterPro:IPR006675" /db_xref="InterPro:IPR011621" /db_xref="InterPro:IPR011624" /db_xref="SubtiList:BG11655" /db_xref="UniProtKB/Swiss-Prot:P46344" /translation="MLKKKAKTKSSSKKWSSFKNARSMHVLLYLLLAAIMFALLFVHV KPETLDLDLFSVSDKTIYAPATVEDQKATEEKKQAAEDAVEDQYTLKKEYTDNRIDLV SSIFDSISEVKKSSEEGSKSPSEKSMVKSVKDKLTSDVNDSISEDSIKTLLKADSEDF SFVRDTVITAVNTVMSSEIPSDKLSDAKDKVEKELKSNSIPSKYLGAATEIGRFAIIP NYVFDPKATEAKRQEASDNVQQVQIKQGQVLVEENDLIDREVYRKLELTGLLNNSNLF KPISGLLIMIGLFIATLVYYFEKQKQNLKFKNQSILLFSIITTLLLVIMEVVSLFQKM EYNNIGYLVPIAAGAILIKLLMNERIAILGSIILAICGSMMFNQGVTGTFNYVIGIYY LISGISGVLFLGKHNARSKILQTGLFVAFINMVVVLSLLLIQNTALSGLEIGTLMLMG VVSGFASSVLIIGLMPFFETGFGILSTMRLLELSNPNHPLLRKILTETPGTYHHSVMV ANLSEAACEAVGANGLLARVGAYYHDLGKTKRPQYFIENQMNIDNPHDKLSPQLSKNI IISHTTDGANMLRSYKFPKELVDIAEQHHGTSLLKFFYYKAKEKGDQITEEEFRYPGP KPQSKEAAIISVADSVEAAVRSMHNPNPERIEKLVRGIISDKLQDGQFSECDLTFKEL DTIAKTLCATLKGIFHSRIEYPEATKKVK*" gene complement(2477880..2480015) /gene="pgpH" /locus_tag="BSU_25330" /old_locus_tag="BSU25330" promotor_-35 2479859..2479864 /Source="Nicolas_upshift_promotors" /id="U1974" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1188 /SigmaFactorBS="gttgccggagcgtaaatggtcttgtcgctgactgaaaacaGG TCTAaatcaagtgtttccgGCTTAACATGTACAAAGAGcaaagcaaacataatggcag c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 2479879 /Source="Nicolas_upshifts" /id="U1974" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1188 /SigmaFactorBS="gttgccggagcgtaaatggtcttgtcgctgactgaaaacaGG TCTAaatcaagtgtttccgGCTTAACATGTACAAAGAGcaaagcaaacataatggcag c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 2479880..2479898 /Source="Nicolas_upshift_promotors" /id="U1974" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1188 /SigmaFactorBS="gttgccggagcgtaaatggtcttgtcgctgactgaaaacaGG TCTAaatcaagtgtttccgGCTTAACATGTACAAAGAGcaaagcaaacataatggcag c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" CDS complement(2480094..2481053) /gene="phoH" /locus_tag="BSU_25340" /old_locus_tag="BSU25340" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:12762842" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12762842; Product type ph: phenotype" /codon_start=1 /transl_table=11 /product="phosphate starvation-induced protein" /protein_id="NP_390412.2" /db_xref="EnsemblGenomes-Gn:BSU25340" /db_xref="EnsemblGenomes-Tr:CAB14476" /db_xref="GOA:P46343" /db_xref="InterPro:IPR003714" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG11337" /db_xref="UniProtKB/Swiss-Prot:P46343" /translation="MTEHLLAMNQKLKNPDEALSLFGNQDSFLKLMEKDLNLNIITRG ETIYVSGDDESFQIADRLLGSLLALIRKGIEISERDVIYAIKMAKKNELEYFESMYEE EITKNAKGKSIRVKTMGQREYVAAMKRNDLVFGIGPAGTGKTYLAVVKAVHALKNGHI KKIILTRPAVEAGESLGFLPGDLKEKVDPYLRPLYDALHDVLGADHTERLMERGIIEI APLAYMRGRTLDDAYVILDEAQNTTPAQMKMFLTRLGFGSKMIITGDVSQIDLPKGVK SGLAVAKEMLKGIDGISMIELDQTDVVRHPLVAKIIEAYDKQN*" gene complement(2480094..2481053) /gene="phoH" /locus_tag="BSU_25340" /old_locus_tag="BSU25340" downshifts complement(2480109) /Source="Nicolas_upshifts" /id="D1313" /incds=0 /nref=1 /ntot=63 /MaxReadThrough="6.04676" /MaxDrop="4.50442" /score="9.12152318" /energy="-13.1" /TU="U1975,U1976,U1977" /idTUdmin="U1978" /TUdmin=1034 /isTUend="FALSE" CDS complement(2481050..2482246) /gene="yqfD" /locus_tag="BSU_25350" /old_locus_tag="BSU25350" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 14523133, 26735940; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="stage IV sporulation protein; putative UDP-glucose-4-epimerase" /protein_id="NP_390413.2" /db_xref="EnsemblGenomes-Gn:BSU25350" /db_xref="EnsemblGenomes-Tr:CAB14477" /db_xref="GOA:P54469" /db_xref="InterPro:IPR010690" /db_xref="SubtiList:BG11654" /db_xref="UniProtKB/Swiss-Prot:P54469" /translation="MKNKWLSFFSGKVQLELTGRGIERLLNECTRQGIPVFHVKKKKE AVSLYIQLQDVHAFRRVRSKFKCKARFINRKGFPFLLLKSKLNIGFTIGFAIFFILLF LLSNMVWKIDVTGAKPETEHQMRQHLNEIGVKKGRLQFLMMSPEKIQKSLTNGIDNIT WVGVDLKGTTIHMKVVEKNEPEKEKYVSPRNIVAKKKATITRMFVQKGQPMAAIHDHV EKGQLLVSGLIGSEDHQQEVASKAEIYGETWYRSEVTVPLETLFNVYTGKVRTKHKLS FGSLAIPIWGMTFKKEELKHPKTEQEKHSLHFLGFKLPVSYVKEQTRESEEALRKYTK EEAVQEGIKLGKQDVEDKIGENGEVKSEKVLHQTVENGKVKLIILYQVIEDIVQTTPI VRETEE*" gene complement(2481050..2482246) /gene="yqfD" /locus_tag="BSU_25350" /old_locus_tag="BSU25350" promotor_-10 complement(2481117..2481136) /Source="Nicolas_upshift_promotors" /id="U1975" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.493506493506494" /psig="0.998001998001998" /xcortree=609 /SigmaFactorBS="aaacggcgaggtgaaaagtgaaaaaGTTTTGCAccagactgt tgagAATGGTAAAGTAAAGTTGATtattctctaccaagttatagaagatatcgttcaa a" /listShort="phoH, yqfF, yqfG, dgkA, S958, cdd, era, S957, yqzL, recO, NA, glyQ, glyS, S955, ccpN, yqfL" /listLong="S954, S953, yqxD, dnaG, S952, sigA, S949, S948, cccA, S947, S946, trmK, yqfO" /label="promotor_-10" upshifts complement(2481122) /Source="Nicolas_upshifts" /id="U1975" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.493506493506494" /psig="0.998001998001998" /xcortree=609 /SigmaFactorBS="aaacggcgaggtgaaaagtgaaaaaGTTTTGCAccagactgt tgagAATGGTAAAGTAAAGTTGATtattctctaccaagttatagaagatatcgttcaa a" /listShort="phoH, yqfF, yqfG, dgkA, S958, cdd, era, S957, yqzL, recO, NA, glyQ, glyS, S955, ccpN, yqfL" /listLong="S954, S953, yqxD, dnaG, S952, sigA, S949, S948, cccA, S947, S946, trmK, yqfO" promotor_-35 complement(2481150..2481157) /Source="Nicolas_upshift_promotors" /id="U1975" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.493506493506494" /psig="0.998001998001998" /xcortree=609 /SigmaFactorBS="aaacggcgaggtgaaaagtgaaaaaGTTTTGCAccagactgt tgagAATGGTAAAGTAAAGTTGATtattctctaccaagttatagaagatatcgttcaa a" /listShort="phoH, yqfF, yqfG, dgkA, S958, cdd, era, S957, yqzL, recO, NA, glyQ, glyS, S955, ccpN, yqfL" /listLong="S954, S953, yqxD, dnaG, S952, sigA, S949, S948, cccA, S947, S946, trmK, yqfO" /label="promotor_-35" promotor_-10 complement(2481197..2481215) /Source="Nicolas_upshift_promotors" /id="U1976" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=741 /SigmaFactorBS="agaggctttgcgaaaatatacaaaagaagaagcAGTTCAAga aggcattaaattGGGTAAACAGGATGTAGAGgataaaataggcgaaaacggcgaggtg a" /listShort="phoH, yqfF, yqfG, dgkA, S958, cdd, era, S957, yqzL, recO" /listLong="NA, glyQ, glyS" /label="promotor_-10" upshifts complement(2481209) /Source="Nicolas_upshifts" /id="U1976" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=741 /SigmaFactorBS="agaggctttgcgaaaatatacaaaagaagaagcAGTTCAAga aggcattaaattGGGTAAACAGGATGTAGAGgataaaataggcgaaaacggcgaggtg a" /listShort="phoH, yqfF, yqfG, dgkA, S958, cdd, era, S957, yqzL, recO" /listLong="NA, glyQ, glyS" promotor_-35 complement(2481230..2481236) /Source="Nicolas_upshift_promotors" /id="U1976" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=741 /SigmaFactorBS="agaggctttgcgaaaatatacaaaagaagaagcAGTTCAAga aggcattaaattGGGTAAACAGGATGTAGAGgataaaataggcgaaaacggcgaggtg a" /listShort="phoH, yqfF, yqfG, dgkA, S958, cdd, era, S957, yqzL, recO" /listLong="NA, glyQ, glyS" /label="promotor_-35" upshifts complement(2481424) /Source="Nicolas_upshifts" /id="U1977" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.97902097902098" /psig="0.97902097902098" /xcortree=910 /SigmaFactorBS="acagtcccgcttgaAACATTAtttaacgtctatacGGGCAAA GTAAGgacaaagcacaagctttcttttggttctttggcaatcccgatctgggggatga c" /listShort="phoH, yqfF, yqfG, dgkA" /listLong="S958, cdd, era, S957, yqzL, recO, NA, glyQ, glyS, S955, ccpN, yqfL, S954, S953, yqxD, dnaG, S952, sigA, S949, S948, cccA" promotor_-10 complement(2481438..2481449) /Source="Nicolas_upshift_promotors" /id="U1977" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.97902097902098" /psig="0.97902097902098" /xcortree=910 /SigmaFactorBS="acagtcccgcttgaAACATTAtttaacgtctatacGGGCAAA GTAAGgacaaagcacaagctttcttttggttctttggcaatcccgatctgggggatga c" /listShort="phoH, yqfF, yqfG, dgkA" /listLong="S958, cdd, era, S957, yqzL, recO, NA, glyQ, glyS, S955, ccpN, yqfL, S954, S953, yqxD, dnaG, S952, sigA, S949, S948, cccA" /label="promotor_-10" promotor_-35 complement(2481464..2481470) /Source="Nicolas_upshift_promotors" /id="U1977" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.97902097902098" /psig="0.97902097902098" /xcortree=910 /SigmaFactorBS="acagtcccgcttgaAACATTAtttaacgtctatacGGGCAAA GTAAGgacaaagcacaagctttcttttggttctttggcaatcccgatctgggggatga c" /listShort="phoH, yqfF, yqfG, dgkA" /listLong="S958, cdd, era, S957, yqzL, recO, NA, glyQ, glyS, S955, ccpN, yqfL, S954, S953, yqxD, dnaG, S952, sigA, S949, S948, cccA" /label="promotor_-35" CDS complement(2482265..2482546) /gene="yqfC" /locus_tag="BSU_25360" /old_locus_tag="BSU25360" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 12662922" /codon_start=1 /transl_table=11 /product="conserved sporulation protein of unknown function" /protein_id="NP_390414.1" /db_xref="EnsemblGenomes-Gn:BSU25360" /db_xref="EnsemblGenomes-Tr:CAB14478" /db_xref="InterPro:IPR022476" /db_xref="InterPro:IPR022477" /db_xref="SubtiList:BG11653" /db_xref="UniProtKB/Swiss-Prot:P54468" /translation="MGQRKNRMKAWLTRALEIPPDVMMDLPRITMVGRLHIYIENHRG LLLFSENEVRLMLKQGQCIISGKNFVIKAILPEEILLEGTIDVVRYVES*" gene complement(2482265..2482546) /gene="yqfC" /locus_tag="BSU_25360" /old_locus_tag="BSU25360" CDS complement(2482603..2483022) /gene="yqfB" /locus_tag="BSU_25370" /old_locus_tag="BSU25370" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_390415.2" /db_xref="EnsemblGenomes-Gn:BSU25370" /db_xref="EnsemblGenomes-Tr:CAB14479" /db_xref="GOA:P54467" /db_xref="InterPro:IPR016788" /db_xref="SubtiList:BG11652" /db_xref="UniProtKB/Swiss-Prot:P54467" /translation="MEDLLTNPLIIAAIIGIISAIFGKKSKEEKQNSQKRKKPQHVQS ASPQKKQSKEDAPAPIPNRMEQARREAEERRRETARNLKGLERDLAAAKQKTVYTKQK MLQVNKDTVVQGIVLGEVFGPPRAKKPHRTMRPARKN*" gene complement(2482603..2483022) /gene="yqfB" /locus_tag="BSU_25370" /old_locus_tag="BSU25370" downshifts complement(2482617) /Source="Nicolas_upshifts" /id="D1314" /incds=0 /nref=232 /ntot=257 /MaxReadThrough="4.55662" /MaxDrop="7.47609" /score="-3.87904232" /energy="-16.8" /TU="U1978" /idTUdmin="U1980" /TUdmin=242 /isTUend="FALSE" CDS complement(2483047..2484042) /gene="floA" /locus_tag="BSU_25380" /old_locus_tag="BSU25380" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:12501411, 22753055" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12501411, 22753055; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="flotillin-like protein involved in membrane lipid rafts" /protein_id="NP_390416.1" /db_xref="EnsemblGenomes-Gn:BSU25380" /db_xref="EnsemblGenomes-Tr:CAB14480" /db_xref="GOA:P54466" /db_xref="InterPro:IPR022853" /db_xref="SubtiList:BG11651" /db_xref="UniProtKB/Swiss-Prot:P54466" /translation="MDPSTLMILAIVAVAIIVLAVFFTFVPVMLWISALAAGVKISIF TLVGMRLRRVIPNRVVNPLIKAHKAGLNVGTNQLESHYLAGGNVDRVVNALIAAQRAN IELTFERCAAIDLAGRDVLEAVQMSVNPKVIETPFIAGVAMDGIEVKAKARITVRANI ERLVGGAGEETIVARVGEGIVSTIGSSDNHKKVLENPDMISQTVLGKGLDSGTAFEIL SIDIADVDIGKNIGAILQTDQAEADKNIAQAKAEERRAMAVAQEQEMRARVEEMRAKV VEAEAEVPLAMAEALREGNIGVMDYMNIKNIDADTEMRDSFGKLTKDPSDEDRKS*" gene complement(2483047..2484042) /gene="floA" /locus_tag="BSU_25380" /old_locus_tag="BSU25380" CDS complement(2484064..2485377) /gene="nfeDA" /locus_tag="BSU_25390" /old_locus_tag="BSU25390" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 22720735, 22753055; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative membrane bound peptidase of unkwnown function" /protein_id="NP_390417.1" /db_xref="EnsemblGenomes-Gn:BSU25390" /db_xref="EnsemblGenomes-Tr:CAB14481" /db_xref="GOA:P54465" /db_xref="InterPro:IPR002810" /db_xref="InterPro:IPR002825" /db_xref="InterPro:IPR029045" /db_xref="SubtiList:BG11650" /db_xref="UniProtKB/Swiss-Prot:P54465" /translation="MLQIKGFRAALLGIFLLSLLGVQLNAKAEKQTVYVIPVEKNVEQ GLASFLSRSLQDAKDAHADHIILDINTPGGLVKSAIDMADLITESEIPVTAYVNKRAL SAGAYIALQADHIYMAPGGKMGAAAIVDGQGNAADQKAQSLWLAEMEDAAVKNNRDPK YALAMADPDIDAKEVGAPKGDLLTLNADKAIEVGYSEGTADNLSTLVKKLGFEKAQIS YAKESFAEKTARWLTNPVIVPILLTIAFLGLTVELFSPGVGLPGTAGLIALLLFFYGH LAAGLAGYETVLLFIAGVILILLEIFLPGGIIGLLGLGAIIASLFLAAGSFTVMAVSL LIASAVSITAFILLTRVLGKRMKFFKKLILNDSTNTESGYVSNQTRTDLMGKVGITFT PLRPSGTVIIDDERLDVVSEGSFTEKDKKVKVIKVEGSRIVVREI*" gene complement(2484064..2485377) /gene="nfeDA" /locus_tag="BSU_25390" /old_locus_tag="BSU25390" promotor_-10 complement(2485413..2485428) /Source="Nicolas_upshift_promotors" /id="U1978" /multdbtbs="SigW" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1696 /SigmaFactorBS="atctttctaagagagatgtctttttttatacataaaaaaaTG AAACCTTTgatacatttgttACGTATGAAGAGAAGGcacttattataaaaggaaggag g" /listShort="yqeZ, yqfA, yqfB, yqfC, yqfD" /listLong="phoH, yqfF, yqfG" /label="promotor_-10" upshifts complement(2485430) /Source="Nicolas_upshifts" /id="U1978" /multdbtbs="SigW" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1696 /SigmaFactorBS="atctttctaagagagatgtctttttttatacataaaaaaaTG AAACCTTTgatacatttgttACGTATGAAGAGAAGGcacttattataaaaggaaggag g" /listShort="yqeZ, yqfA, yqfB, yqfC, yqfD" /listLong="phoH, yqfF, yqfG" promotor_-35 complement(2485441..2485450) /Source="Nicolas_upshift_promotors" /id="U1978" /multdbtbs="SigW" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1696 /SigmaFactorBS="atctttctaagagagatgtctttttttatacataaaaaaaTG AAACCTTTgatacatttgttACGTATGAAGAGAAGGcacttattataaaaggaaggag g" /listShort="yqeZ, yqfA, yqfB, yqfC, yqfD" /listLong="phoH, yqfF, yqfG" /label="promotor_-35" CDS complement(2485508..2485954) /gene="yqeY" /locus_tag="BSU_25400" /old_locus_tag="BSU25400" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 17284460, 22720735, 25149203" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function with tRNA aminoacid amidase domain" /protein_id="NP_390418.1" /db_xref="EnsemblGenomes-Gn:BSU25400" /db_xref="EnsemblGenomes-Tr:CAB14482" /db_xref="GOA:P54464" /db_xref="InterPro:IPR003789" /db_xref="InterPro:IPR019004" /db_xref="InterPro:IPR023168" /db_xref="PDB:1NG6" /db_xref="SubtiList:BG11649" /db_xref="UniProtKB/Swiss-Prot:P54464" /translation="MSLLERLNQDMKLYMKNREKDKLTVVRMVKASLQNEAIKLKKDS LTEDEELTVLSRELKQRKDSLQEFSNANRLDLVDKVQKELDILEVYLPEQLSEEELRT IVNETIAEVGASSKADMGKVMGAIMPKVKGKADGSLINKLVSSQLS*" gene complement(2485508..2485954) /gene="yqeY" /locus_tag="BSU_25400" /old_locus_tag="BSU25400" downshifts complement(2485521) /Source="Nicolas_upshifts" /id="D1315" /incds=0 /nref=248 /ntot=267 /MaxReadThrough="5.1355" /MaxDrop="8.31948" /score="17.2548348" /energy="-10.3" /TU="U1980" /idTUdmin="U1983" /TUdmin=1760 /isTUend="FALSE" downshifts complement(2485719) /Source="Nicolas_upshifts" /id="D1316" /incds=1 /nref=1 /ntot=34 /MaxReadThrough="8.99916" /MaxDrop="1.9798" /score="17.2548348" /energy="-10.3" /TU="U1980" /idTUdmin="U1983" /TUdmin=1562 /isTUend="FALSE" CDS complement(2485969..2486142) /gene="rpsU" /locus_tag="BSU_25410" /old_locus_tag="BSU25410" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:12682299, 22720735, 23002217, 25035996" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12682299, 22720735, 23002217, 25035996; Product type s: structure" /codon_start=1 /transl_table=11 /product="ribosomal protein S21" /protein_id="NP_390419.1" /db_xref="EnsemblGenomes-Gn:BSU25410" /db_xref="EnsemblGenomes-Tr:CAB14483" /db_xref="GOA:P21478" /db_xref="InterPro:IPR001911" /db_xref="InterPro:IPR018278" /db_xref="SubtiList:BG11648" /db_xref="UniProtKB/Swiss-Prot:P21478" /translation="MSKTVVRKNESLEDALRRFKRSVSKTGTLQEARKREFYEKPSVK RKKKSEAARKRKF*" gene complement(2485969..2486142) /gene="rpsU" /locus_tag="BSU_25410" /old_locus_tag="BSU25410" misc_feature 2486078..2486082 /Source="Nicolas_upshift_promotors" /id="U1979" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.877122877122877" /psig="0.113886113886114" /xcortree=55 /SigmaFactorBS="tttttcataaaattcacgctttcttgcttcttgcaaagtacc tgtctttgatacaCTGCGtttgaagcgacgaagagcatcttcaagcgattcgtttttt c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 2486083 /Source="Nicolas_upshifts" /id="U1979" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.877122877122877" /psig="0.113886113886114" /xcortree=55 /SigmaFactorBS="tttttcataaaattcacgctttcttgcttcttgcaaagtacc tgtctttgatacaCTGCGtttgaagcgacgaagagcatcttcaagcgattcgtttttt c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 complement(2486203..2486222) /Source="Nicolas_upshift_promotors" /id="U1980" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.547452547452547" /psig="0.998001998001998" /xcortree=2702 /SigmaFactorBS="ggcagtcgcactcatgacggaaaagtgaactcactTAGTTGA CctgactgatggctTATATTATAATGTCAAAGTAcatgtttatatgtgtaacttaaag g" /listShort="rpsU, yqeY, yqeZ, yqfA, yqfB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2486218) /Source="Nicolas_upshifts" /id="U1980" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.547452547452547" /psig="0.998001998001998" /xcortree=2702 /SigmaFactorBS="ggcagtcgcactcatgacggaaaagtgaactcactTAGTTGA CctgactgatggctTATATTATAATGTCAAAGTAcatgtttatatgtgtaacttaaag g" /listShort="rpsU, yqeY, yqeZ, yqfA, yqfB" /GFF_Attribute="listLong" promotor_-35 complement(2486236..2486243) /Source="Nicolas_upshift_promotors" /id="U1980" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.547452547452547" /psig="0.998001998001998" /xcortree=2702 /SigmaFactorBS="ggcagtcgcactcatgacggaaaagtgaactcactTAGTTGA CctgactgatggctTATATTATAATGTCAAAGTAcatgtttatatgtgtaacttaaag g" /listShort="rpsU, yqeY, yqeZ, yqfA, yqfB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 2486261..2486266 /Source="Nicolas_upshift_promotors" /id="U1981" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.975024975024975" /psig="0.975024975024975" /xcortree=971 /SigmaFactorBS="taagccatcagtcaggtcaactaagtgagttcacttttccGT CATGagtgcgactgcctgtCTATATAATGAAAGAAAGGggttggtgaataggatgtta a" /listShort="yqeW" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 2486281 /Source="Nicolas_upshifts" /id="U1981" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.975024975024975" /psig="0.975024975024975" /xcortree=971 /SigmaFactorBS="taagccatcagtcaggtcaactaagtgagttcacttttccGT CATGagtgcgactgcctgtCTATATAATGAAAGAAAGGggttggtgaataggatgtta a" /listShort="yqeW" /GFF_Attribute="listLong" promotor_-10 2486282..2486300 /Source="Nicolas_upshift_promotors" /id="U1981" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.975024975024975" /psig="0.975024975024975" /xcortree=971 /SigmaFactorBS="taagccatcagtcaggtcaactaagtgagttcacttttccGT CATGagtgcgactgcctgtCTATATAATGAAAGAAAGGggttggtgaataggatgtta a" /listShort="yqeW" /GFF_Attribute="listLong" /label="promotor_-10" CDS 2486315..2487238 /gene="yqeW" /locus_tag="BSU_25420" /old_locus_tag="BSU25420" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406, 22720735; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative Na+/anion cotransporter" /protein_id="NP_390420.2" /db_xref="EnsemblGenomes-Gn:BSU25420" /db_xref="EnsemblGenomes-Tr:CAB14484" /db_xref="GOA:P54463" /db_xref="InterPro:IPR003841" /db_xref="InterPro:IPR004633" /db_xref="SubtiList:BG11647" /db_xref="UniProtKB/Swiss-Prot:P54463" /translation="MLILISFTALILFFLAGMNMLRKGLISMAYSKIEERLLLFTDHP LKAFLISIVFTGILQSSSAFMVIVIGFVSAGVLSFKRTIPMILGTNVGSTFTTEFIAI KMDIVIWVLLIGGLLFFLTGRYPLKQLGTSFLGLGIIFFCISGFSHLAGPLTKLKTGA DVLYHVNDSNWSALLIGMVLTAIIHSSSVCIGILMSFMNEGIIGLTQAMSVVLGSNIG TCITAVMAAVSGGYAAKQTAYAHVVFNVLGVALVLPFLTAATGFVEQLSPDPAQKIAH FSLLFNVVTALLFLPLTNLFYRLIHLLIPAK*" gene 2486315..2487238 /gene="yqeW" /locus_tag="BSU_25420" /old_locus_tag="BSU25420" CDS complement(2487275..2488630) /gene="mtaB" /locus_tag="BSU_25430" /old_locus_tag="BSU25430" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:6163767, 9023197, 10572129, 15339930, 18252828, 8844851, 20472640, 20584901, 27913733" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 6163767, 9023197, 10572129, 15339930, 18252828, 8844851, 20472640, 20584901, 27913733; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="tRNA N(6)-threonylcarbamoyladenosine (t(6)A) methylthiotransferase" /protein_id="NP_390421.1" /db_xref="EnsemblGenomes-Gn:BSU25430" /db_xref="EnsemblGenomes-Tr:CAB14485" /db_xref="GOA:P54462" /db_xref="InterPro:IPR002792" /db_xref="InterPro:IPR005839" /db_xref="InterPro:IPR006467" /db_xref="InterPro:IPR006638" /db_xref="InterPro:IPR007197" /db_xref="InterPro:IPR013848" /db_xref="InterPro:IPR020612" /db_xref="InterPro:IPR023404" /db_xref="InterPro:IPR034557" /db_xref="SubtiList:BG11646" /db_xref="UniProtKB/Swiss-Prot:P54462" /translation="MATVAFHTLGCKVNHYETEAIWQLFKEAGYERRDFEQTADVYVI NTCTVTNTGDKKSRQVIRRAIRQNPDGVICVTGCYAQTSPAEIMAIPGVDIVVGTQDR EKMLGYIDQYREERQPINGVSNIMKARVYEELDVPAFTDRTRASLKIQEGCNNFCTFC IIPWARGLLRSRDPEEVIKQAQQLVDAGYKEIVLTGIHTGGYGEDMKDYNFAKLLSEL DTRVEGVKRIRISSIEASQITDEVIEVLDRSDKIVNHLHIPIQSGSNTVLKRMRRKYT MEFFADRLNKLKKALPGLAVTSDVIVGFPGETEEEFMETYNFIKEHKFSELHVFPYSK RTGTPAARMEDQVDENVKNERVHRLIALSDQLAKEYASQYENEVLEIIPEEAFKETEE ENMFVGYTDNYMKVVFKGTEDMIGKIVKVKILKAGYPYNEGQFVRVVEDEITEHMRLS S*" gene complement(2487275..2488630) /gene="mtaB" /locus_tag="BSU_25430" /old_locus_tag="BSU25430" downshifts complement(2487281) /Source="Nicolas_upshifts" /id="D1317" /incds=0 /nref=208 /ntot=260 /MaxReadThrough="1.95578" /MaxDrop="6.05381" /score="30.7201786" /energy="-11.3" /TU="NA" /idTUdmin="U1983" /TUdmin=0 /isTUend="TRUE" CDS complement(2488630..2489400) /gene="rsmE" /locus_tag="BSU_25440" /old_locus_tag="BSU25440" /EC_number="2.1.1.193" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 9023197, 10383760, 14517985, 16014871, 16431987, 22925577, 24598751; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="methylase of U1498 in 16S rRNA" /protein_id="NP_390422.1" /db_xref="EnsemblGenomes-Gn:BSU25440" /db_xref="EnsemblGenomes-Tr:CAB14486" /db_xref="GOA:P54461" /db_xref="InterPro:IPR006700" /db_xref="InterPro:IPR015947" /db_xref="InterPro:IPR029026" /db_xref="InterPro:IPR029028" /db_xref="PDB:1VHK" /db_xref="SubtiList:BG11645" /db_xref="UniProtKB/Swiss-Prot:P54461" /translation="MQRYFIELTKQQIEEAPTFSITGEEVHHIVNVMRMNEGDQIICC SQDGFEAKCELQSVSKDKVSCLVIEWTNENRELPIKVYIASGLPKGDKLEWIIQKGTE LGAHAFIPFQAARSVVKLDDKKAKKKRERWTKIAKEAAEQSYRNEVPRVMDVHSFQQL LQRMQDFDKCVVAYEESSKQGEISAFSAIVSSLPKGSSLLIVFGPEGGLTEAEVERLT EQDGVTCGLGPRILRTETAPLYALSAISYQTELLRGDQ*" gene complement(2488630..2489400) /gene="rsmE" /locus_tag="BSU_25440" /old_locus_tag="BSU25440" CDS complement(2489423..2490358) /gene="prmA" /locus_tag="BSU_25450" /old_locus_tag="BSU25450" /EC_number="2.1.1.-" /function="16.6: Maintain" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 17215866, 18611379; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="ribosomal protein L11 methyltransferase" /protein_id="NP_390423.2" /db_xref="EnsemblGenomes-Gn:BSU25450" /db_xref="EnsemblGenomes-Tr:CAB14487" /db_xref="GOA:P54460" /db_xref="InterPro:IPR004498" /db_xref="InterPro:IPR029063" /db_xref="SubtiList:BG11644" /db_xref="UniProtKB/Swiss-Prot:P54460" /translation="MKWSELSIHTTHEAVEPISNILHEAGASGVVIEDPLDLIKEREN VYGEIYQLDPNDYPDEGVIVKAYLPVNSFLGETVDGIKETINNLLLYNIDLGRNHITI SEVNEEEWATAWKKYYHPVKISEKFTIVPTWEEYTPVHTDELIIEMDPGMAFGTGTHP TTVLCIQALERFVQKGDKVIDVGTGSGILSIAAAMLEAESVHAYDLDPVAVESARLNL KLNKVSDIAQVKQNNLLDGIEGEHDVIVANILAEVILRFTSQAYSLLKEGGHFITSGI IGHKKQEVKEALEQAGFTIVEILSMEDWVSIIAKK*" gene complement(2489423..2490358) /gene="prmA" /locus_tag="BSU_25450" /old_locus_tag="BSU25450" CDS complement(2490383..2491510) /gene="dnaJ" /locus_tag="BSU_25460" /old_locus_tag="BSU25460" /function="16.6: Maintain" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:10383760, 10658654, 16385044, 16952052" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10383760, 10658654, 16385044, 16952052; Product type f: factor" /codon_start=1 /transl_table=11 /product="co-factor of molecular chaperone" /protein_id="NP_390424.2" /db_xref="EnsemblGenomes-Gn:BSU25460" /db_xref="EnsemblGenomes-Tr:CAB14488" /db_xref="GOA:P17631" /db_xref="InterPro:IPR001305" /db_xref="InterPro:IPR001623" /db_xref="InterPro:IPR002939" /db_xref="InterPro:IPR008971" /db_xref="InterPro:IPR012724" /db_xref="InterPro:IPR018253" /db_xref="InterPro:IPR036410" /db_xref="InterPro:IPR036869" /db_xref="SubtiList:BG10665" /db_xref="UniProtKB/Swiss-Prot:P17631" /translation="MSKRDYYEVLGVSKSASKDEIKKAYRKLSKKYHPDINKEAGSDE KFKEVKEAYETLSDDQKRAHYDQFGHTDPNQGFGGGGFGGGDFGGFGFDDIFSSIFGG GTRRRDPNAPRQGADLQYTMTLSFEDAAFGKETTIEIPREETCETCKGSGAKPGTNPE TCSHCGGSGQLNVEQNTPFGKVVNRRVCHHCEGTGKIIKNKCADCGGKGKIKKRKKIN VTIPAGVDDGQQLRLSGQGEPGINGGPAGDLFVVFHVRAHEFFERDGDDIYCEMPLTF AQAALGDEVEVPTLHGKVKLKIPAGTQTGTKFRLRGKGVQNVRGYGQGDQHIVVRVVT PTNLTDKQKDIIREFAEVSGNLPDEQEMSFFDKVKRAFKGD*" gene complement(2490383..2491510) /gene="dnaJ" /locus_tag="BSU_25460" /old_locus_tag="BSU25460" misc_feature 2491427..2491430 /Source="Nicolas_upshift_promotors" /id="U1982" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.966033966033966" /psig="0.014985014985015" /xcortree=39 /SigmaFactorBS="tttcatctgatccggcttctttgttaatatcaggatgatatt tttttgaCAGCttccgataagcttttttaatttcatcctttgaagcgctcttacttac t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 2491438 /Source="Nicolas_upshifts" /id="U1982" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.966033966033966" /psig="0.014985014985015" /xcortree=39 /SigmaFactorBS="tttcatctgatccggcttctttgttaatatcaggatgatatt tttttgaCAGCttccgataagcttttttaatttcatcctttgaagcgctcttacttac t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" S_feature complement(2491511..2491688) /Source="Nicolas_S_feature" /locus_tag="new_2625913_2626090_c" /HighExp="Heat, dia15, H2O2, Diami, G135, G150, G180, LPhT, Etha, Oxctl" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.357489" /TUshortSig="SigA, SigA" /TUshortPSig="1, 1" /TUlongSig="SigGF" /TUlongPSig="0.978" /label="S959" misc_RNA 2491550..2491640 /gene="surC" /locus_tag="BSU_misc_RNA_79" /product="sporulation-related small untranslated RNA" /experiment="publication(s) with functional evidences, PMID:16385044" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16385044; Product type n: RNA" gene 2491550..2491640 /gene="surC" /locus_tag="BSU_misc_RNA_79" CDS complement(2491710..2493545) /gene="dnaK" /locus_tag="BSU_25470" /old_locus_tag="BSU25470" /function="16.6: Maintain" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:10074100, 12224648, 12799007, 17407764, 22938038, 25355936, 27148221" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10074100, 12224648, 12799007, 17407764, 22938038, 25355936, 27148221; Product type f: factor" /codon_start=1 /transl_table=11 /product="molecular chaperone, ATP-dependent" /protein_id="NP_390425.1" /db_xref="EnsemblGenomes-Gn:BSU25470" /db_xref="EnsemblGenomes-Tr:CAB14489" /db_xref="GOA:P17820" /db_xref="InterPro:IPR012725" /db_xref="InterPro:IPR013126" /db_xref="InterPro:IPR018181" /db_xref="InterPro:IPR029047" /db_xref="InterPro:IPR029048" /db_xref="PDB:2FZO" /db_xref="SubtiList:BG10664" /db_xref="UniProtKB/Swiss-Prot:P17820" /translation="MSKVIGIDLGTTNSCVAVLEGGEPKVIANAEGNRTTPSVVAFKN GERQVGEVAKRQSITNPNTIMSIKRHMGTDYKVEIEGKDYTPQEVSAIILQHLKSYAE SYLGETVSKAVITVPAYFNDAERQATKDAGKIAGLEVERIINEPTAAALAYGLDKTDE DQTILVYDLGGGTFDVSILELGDGVFEVRSTAGDNRLGGDDFDQVIIDHLVSEFKKEN GIDLSKDKMALQRLKDAAEKAKKDLSGVSSTQISLPFITAGEAGPLHLELTLTRAKFE ELSSHLVERTMGPVRQALQDAGLSASEIDKVILVGGSTRIPAVQEAIKKETGKEAHKG VNPDEVVALGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK SQVFSTAADNQTAVDIHVLQGERPMSADNKTLGRFQLTDIPPAPRGVPQIEVSFDIDK NGIVNVRAKDLGTGKEQNITIKSSSGLSDEEIERMVKEAEENADADAKKKEEIEVRNE ADQLVFQTEKTLKDLEGKVDEEQVKKANDAKDALKAAIEKNEFEEIKAKKDELQTIVQ ELSMKLYEEAAKAQQAQGGANAEGKADDNVVDAEYEEVNDDQNKK*" gene complement(2491710..2493545) /gene="dnaK" /locus_tag="BSU_25470" /old_locus_tag="BSU25470" downshifts complement(2491733) /Source="Nicolas_upshifts" /id="D1318" /incds=0 /nref=130 /ntot=247 /MaxReadThrough="8.0737" /MaxDrop="4.023" /score="21.9400858" /energy="-13.4" /TU="U1983,U1985" /idTUdmin="U1984" /TUdmin=3565 /isTUend="FALSE" CDS complement(2493569..2494132) /gene="grpE" /locus_tag="BSU_25480" /old_locus_tag="BSU25480" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:9303302, 10383760, 12682299, 17289679, 21546913, 22720735, 22938038, 26913285" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9303302, 10383760, 12682299, 17289679, 21546913, 22720735, 22938038, 26913285; Product type r: regulator" /codon_start=1 /transl_table=11 /product="nucleotide exchange factor for DnaK activity" /protein_id="NP_390426.1" /db_xref="EnsemblGenomes-Gn:BSU25480" /db_xref="EnsemblGenomes-Tr:CAB14490" /db_xref="GOA:P15874" /db_xref="InterPro:IPR000740" /db_xref="InterPro:IPR009012" /db_xref="InterPro:IPR013805" /db_xref="PDB:2G61" /db_xref="SubtiList:BG10663" /db_xref="UniProtKB/Swiss-Prot:P15874" /translation="MSEEKQTVEQNETEEQEIIEEQAAADEQQEETNESELLQNQINE LQGLLEEKENKLLRVQADFENYKRRSRLEMEASQKYRSQNIVTDLLPALDSFERALQV EADNEQTKSLLQGMEMVHRQLVEALKKEGVEAIEAVGQEFDPNLHQAVMQAEDENYGS NIVVEEMQKGYKLKDRVIRPSMVKVNQ*" gene complement(2493569..2494132) /gene="grpE" /locus_tag="BSU_25480" /old_locus_tag="BSU25480" S_feature complement(2494133..2494203) /Source="Nicolas_S_feature" /locus_tag="new_2628535_2628605_c" /HighExp="LPhT, dia15, Heat, Etha, Diami, dia5, H2O2, T-0.40H, T0.30H, T0.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="1, 1" /TUlongSig="SigGF" /TUlongPSig="0.978" /label="S960" CDS complement(2494204..2495235) /gene="hrcA" /locus_tag="BSU_25490" /old_locus_tag="BSU25490" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:10555317, 12082092, 15109714, 16872404, 16585746, 22720735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10555317, 12082092, 15109714, 16872404, 16585746, 22720735; Product type r : regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator of heat-shock genes" /protein_id="NP_390427.1" /db_xref="EnsemblGenomes-Gn:BSU25490" /db_xref="EnsemblGenomes-Tr:CAB14491" /db_xref="GOA:P25499" /db_xref="InterPro:IPR002571" /db_xref="InterPro:IPR021153" /db_xref="InterPro:IPR029016" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG10662" /db_xref="UniProtKB/Swiss-Prot:P25499" /translation="MLTNRQLLILQVIINDFIKSAQPVGSRTLSKKDEITFSSATIRN EMADLEELGFIEKTHSSSGRVPSEKGYRYYVDHLLSPVKLTKSDLDQIHSIFKEKIFE LEKTVQKSAQILSDLTNYTSIVLGPKLSENYLKQIQIIPIQPDMAVAILVTNTGHVEN KTINFPTKMDLSDIEKLVNILNDRLSGVPMDELNERIFKEVVMYLRQHIKNYDNILDA LRSTFHSTNHVEKLFFGGKINMLNQPEFHDITRVRSLLSLIEKEQDVLKLVQSPHTGI SIKIGKENDYEEMENCSLITASYSVDQKQIGSIAIIGPTRMNYSRVVSLLQHVTSDLS KALTSLYDE*" gene complement(2494204..2495235) /gene="hrcA" /locus_tag="BSU_25490" /old_locus_tag="BSU25490" promotor_-10 complement(2495276..2495295) /Source="Nicolas_upshift_promotors" /id="U1983" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.629370629370629" /psig=1 /xcortree=2023 /SigmaFactorBS="tgaagtttttggcgcttttttgggtgagttatAATTGACAtt tttcttgtggttTGATACTTTTGTTATAGAATtagcactcgcttattgagagtgctaa c" /listShort="hrcA, S960, grpE, dnaK, S959, dnaJ, prmA, rsmE, rimO" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2495289) /Source="Nicolas_upshifts" /id="U1983" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.629370629370629" /psig=1 /xcortree=2023 /SigmaFactorBS="tgaagtttttggcgcttttttgggtgagttatAATTGACAtt tttcttgtggttTGATACTTTTGTTATAGAATtagcactcgcttattgagagtgctaa c" /listShort="hrcA, S960, grpE, dnaK, S959, dnaJ, prmA, rsmE, rimO" /GFF_Attribute="listLong" promotor_-35 complement(2495310..2495317) /Source="Nicolas_upshift_promotors" /id="U1983" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.629370629370629" /psig=1 /xcortree=2023 /SigmaFactorBS="tgaagtttttggcgcttttttgggtgagttatAATTGACAtt tttcttgtggttTGATACTTTTGTTATAGAATtagcactcgcttattgagagtgctaa c" /listShort="hrcA, S960, grpE, dnaK, S959, dnaJ, prmA, rsmE, rimO" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2495316..2496455) /gene="hemN" /locus_tag="BSU_25500" /old_locus_tag="BSU25500" /EC_number="1.3.98.3" /function="16.10: Respire" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:8757728, 9371469, 10498703, 12196143, 19944166" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8757728, 9371469, 10498703, 12196143, 19944166; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="coproporphyrinogen III oxidase" /protein_id="NP_390428.2" /db_xref="EnsemblGenomes-Gn:BSU25500" /db_xref="EnsemblGenomes-Tr:CAB14492" /db_xref="GOA:P54304" /db_xref="InterPro:IPR004559" /db_xref="InterPro:IPR006638" /db_xref="InterPro:IPR007197" /db_xref="InterPro:IPR010723" /db_xref="InterPro:IPR013785" /db_xref="InterPro:IPR034505" /db_xref="SubtiList:BG11395" /db_xref="UniProtKB/Swiss-Prot:P54304" /translation="MKSAYIHIPFCEHICHYCDFNKYFIQSQPVDEYLNALEQEMINT IAKTGQPDLKTIFIGGGTPTSLSEEQLKKLMDMINRVLKPSSDLSEFAVEANPDDLSA EKLKILKEAGVNRLSFGVQTFEDDLLEKIGRVHKQKDVFTSFERAREIGFENISLDLM FGLPGQTLKHLEHSINTALSLDAEHYSVYSLIVEPKTVFYNLMQKGRLHLPPQEQEAE MYEIVMSKMEAHGIHQYEISNFAKAGMESKHNLTYWSNEQYFGFGAGAHGYIGGTRTV NVGPVKHYIDLIAEKGFPYRDTHEVTTEEQIEEEMFLGLRKTAGVSKKRFAEKYGRSL DGLFPSVLKDLAEKGLIHNSESAVYLTHQGKLLGNEVFGAFLGEL*" gene complement(2495316..2496455) /gene="hemN" /locus_tag="BSU_25500" /old_locus_tag="BSU25500" promotor_-10 complement(2496328..2496339) /Source="Nicolas_upshift_promotors" /id="U1984" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.978021978021978" /psig="0.978021978021978" /xcortree=802 /SigmaFactorBS="aaatattttattcaaagtcagccagtcgacgagTATTTAAac gcactcgaacaGGAAATGATAAAtacaatagcaaaaaccgggcagcctgatctcaaaa c" /GFF_Attribute="listShort" /listLong="hrcA, S960, grpE, dnaK, S959, dnaJ" /label="promotor_-10" upshifts complement(2496332) /Source="Nicolas_upshifts" /id="U1984" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.978021978021978" /psig="0.978021978021978" /xcortree=802 /SigmaFactorBS="aaatattttattcaaagtcagccagtcgacgagTATTTAAac gcactcgaacaGGAAATGATAAAtacaatagcaaaaaccgggcagcctgatctcaaaa c" /GFF_Attribute="listShort" /listLong="hrcA, S960, grpE, dnaK, S959, dnaJ" promotor_-35 complement(2496353..2496359) /Source="Nicolas_upshift_promotors" /id="U1984" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.978021978021978" /psig="0.978021978021978" /xcortree=802 /SigmaFactorBS="aaatattttattcaaagtcagccagtcgacgagTATTTAAac gcactcgaacaGGAAATGATAAAtacaatagcaaaaaccgggcagcctgatctcaaaa c" /GFF_Attribute="listShort" /listLong="hrcA, S960, grpE, dnaK, S959, dnaJ" /label="promotor_-35" CDS complement(2496508..2498346) /gene="lepA" /locus_tag="BSU_25510" /old_locus_tag="BSU25510" /function="16.2: Construct biomass (Anabolism)" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 12511492, 17110332, 22720735; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="ribosomal elongation factor, GTPase" /protein_id="NP_390429.1" /db_xref="EnsemblGenomes-Gn:BSU25510" /db_xref="EnsemblGenomes-Tr:CAB14493" /db_xref="GOA:P37949" /db_xref="InterPro:IPR000640" /db_xref="InterPro:IPR000795" /db_xref="InterPro:IPR004161" /db_xref="InterPro:IPR005225" /db_xref="InterPro:IPR006297" /db_xref="InterPro:IPR009000" /db_xref="InterPro:IPR013842" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR031157" /db_xref="InterPro:IPR035647" /db_xref="InterPro:IPR035654" /db_xref="SubtiList:BG10441" /db_xref="UniProtKB/Swiss-Prot:P37949" /translation="MTDKEKRLERQSRIRNFSIIAHIDHGKSTLADRILEKTSAITQR EMKEQLLDSMDLERERGITIKLNSVQLKYKAKDGEEYIFHLIDTPGHVDFTYEVSRSL AACEGAILVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPSAEPERVRQEVEDV IGLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDPEAPLKALIFDSLYDAYRGVVA YIRVVEGTVKPGQKIKMMATGKEFEVTEVGVFTPKATPTNELTVGDVGFLTASIKNVG DTRVGDTITSAANPAEEALPGYRKLNPMVYCGLYPIDTAKYNDLREALEKLELNDSSL QYEAETSQALGFGFRCGFLGMLHMEIIQERIEREFNIDLITTAPSVIYDVYMTDGEKV VVDNPSNMPDPQKIERVEEPYVKATMMVPNDYVGAVMELCQGKRGNFIDMQYLDANRV SIIYDMPLAEIVYEFFDQLKSSTKGYASFDYELIGYKPSKLVKMDIMLNGEKIDALSF IVHRDYAYERGKVIVEKLKELIPRQQFEVPVQAAIGQKIVARSTIKAMRKNVLAKCYG GDISRKRKLLEKQKEGKRRMKQVGSVEVPQEAFMAVLKMDDSPKKQ*" gene complement(2496508..2498346) /gene="lepA" /locus_tag="BSU_25510" /old_locus_tag="BSU25510" downshifts complement(2496530) /Source="Nicolas_upshifts" /id="D1319" /incds=0 /nref=15 /ntot=213 /MaxReadThrough="5.2925" /MaxDrop="3.979" /score="5.45344919" /energy="-14" /TU="U1985" /idTUdmin="U1984" /TUdmin="-1232" /isTUend="FALSE" promotor_-10 complement(2498381..2498400) /Source="Nicolas_upshift_promotors" /id="U1985" /multdbtbs="SigA" /comp="M16" /sig="SigA" /pcomp="0.701298701298701" /psig=1 /xcortree=2588 /SigmaFactorBS="cccagatatgatagggaacttttctctttcttgttttaCATT GaatctttacaatcctATTGATATAATCTAAGCTAGtgtattttgcgtttaatagtag g" /listShort="lepA, hemN, hrcA, S960, grpE, dnaK, S959, dnaJ, prmA, rsmE, rimO" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2498398) /Source="Nicolas_upshifts" /id="U1985" /multdbtbs="SigA" /comp="M16" /sig="SigA" /pcomp="0.701298701298701" /psig=1 /xcortree=2588 /SigmaFactorBS="cccagatatgatagggaacttttctctttcttgttttaCATT GaatctttacaatcctATTGATATAATCTAAGCTAGtgtattttgcgtttaatagtag g" /listShort="lepA, hemN, hrcA, S960, grpE, dnaK, S959, dnaJ, prmA, rsmE, rimO" /GFF_Attribute="listLong" promotor_-35 complement(2498416..2498420) /Source="Nicolas_upshift_promotors" /id="U1985" /multdbtbs="SigA" /comp="M16" /sig="SigA" /pcomp="0.701298701298701" /psig=1 /xcortree=2588 /SigmaFactorBS="cccagatatgatagggaacttttctctttcttgttttaCATT GaatctttacaatcctATTGATATAATCTAAGCTAGtgtattttgcgtttaatagtag g" /listShort="lepA, hemN, hrcA, S960, grpE, dnaK, S959, dnaJ, prmA, rsmE, rimO" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2498480..2498818) /gene="yqxA" /locus_tag="BSU_25520" /old_locus_tag="BSU25520" /function="18: Unknown function" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_390430.1" /db_xref="EnsemblGenomes-Gn:BSU25520" /db_xref="EnsemblGenomes-Tr:CAB14494" /db_xref="InterPro:IPR020534" /db_xref="SubtiList:BG10440" /db_xref="UniProtKB/Swiss-Prot:P38425" /translation="MIAYFGKCLLLVTIMFLGVLFGMQQANHGMLSMKGYHDPSLKGA FTLTDGKDNEKEASILGETVTAKDLVEKQKELEKVETFNMFSKAGKALSDTVTNTAQS MYEWIRDMNQ*" gene complement(2498480..2498818) /gene="yqxA" /locus_tag="BSU_25520" /old_locus_tag="BSU25520" downshifts complement(2498486) /Source="Nicolas_upshifts" /id="D1320" /incds=0 /nref=11 /ntot=43 /MaxReadThrough="2.553" /MaxDrop="3.8126" /score="5.45344919" /energy="-14" /TU="NA" /idTUdmin="U1986" /TUdmin=2 /isTUend="TRUE" CDS complement(2498835..2500040) /gene="spoIIP" /locus_tag="BSU_25530" /old_locus_tag="BSU25530" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:17376078, 23834622" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 17376078, 23834622; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="spore autolysin (stage II sporulation)" /protein_id="NP_390431.1" /db_xref="EnsemblGenomes-Gn:BSU25530" /db_xref="EnsemblGenomes-Tr:CAB14495" /db_xref="GOA:P37968" /db_xref="InterPro:IPR010897" /db_xref="SubtiList:BG10439" /db_xref="UniProtKB/Swiss-Prot:P37968" /translation="MRNKRRNRQIVVAVNGGKAVKAIFLFIVSLIVIFVLSGVLTSLR PELRPSSDSFYGIAEELPGDVFAHLLQMENHYFASDLSQTDSSFHLSRLSLKLATSIN LEDPRSFLGRELPGFAQFDTEILLAGQGTDYTNMPAESPPPSKVMEEEREANLAEIEK QQTQSDNAQKDPPKQTTGDKKVVFIYHTHNTESYLPLLKGETDPDMARHSKANVTLVG DMFGQALESQGIGATVNKTDIQSKLNKKGLNYARSYDESRPVVKDALASNKNLQYIID IHRDSRRKKDTTATIKGKSYARVAFVVGKKSKNFEENYKIASELHKLMEKKYPGLSTG VFSKGSPGDNGVYNQDLTDRALLLEFGGVDNNLEELQRAANAAADVFSEMYWDAEKVN AASGETKKQ*" gene complement(2498835..2500040) /gene="spoIIP" /locus_tag="BSU_25530" /old_locus_tag="BSU25530" promotor_-10 complement(2500060..2500078) /Source="Nicolas_upshift_promotors" /id="U1986" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp="0.58941058941059" /psig="0.58941058941059" /xcortree=451 /SigmaFactorBS="caagaaaacaaaggctcctacaatcactaaacaGTTCTActt cctctagcttgtTCATAGAGTAATTACTAGAcaagcgctggagggattcaatgagaaa t" /listShort="spoIIP, yqxA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2500072) /Source="Nicolas_upshifts" /id="U1986" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp="0.58941058941059" /psig="0.58941058941059" /xcortree=451 /SigmaFactorBS="caagaaaacaaaggctcctacaatcactaaacaGTTCTActt cctctagcttgtTCATAGAGTAATTACTAGAcaagcgctggagggattcaatgagaaa t" /listShort="spoIIP, yqxA" /GFF_Attribute="listLong" promotor_-35 complement(2500094..2500099) /Source="Nicolas_upshift_promotors" /id="U1986" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp="0.58941058941059" /psig="0.58941058941059" /xcortree=451 /SigmaFactorBS="caagaaaacaaaggctcctacaatcactaaacaGTTCTActt cctctagcttgtTCATAGAGTAATTACTAGAcaagcgctggagggattcaatgagaaa t" /listShort="spoIIP, yqxA" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2500103..2501209) /gene="gpr" /locus_tag="BSU_25540" /old_locus_tag="BSU25540" /EC_number="3.4.24.78" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:10666631, 10986255, 12807468, 23927687" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10666631, 10986255, 12807468, 23927687; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="spore germination protease" /protein_id="NP_390432.1" /db_xref="EnsemblGenomes-Gn:BSU25540" /db_xref="EnsemblGenomes-Tr:CAB14496" /db_xref="GOA:P22322" /db_xref="InterPro:IPR005080" /db_xref="InterPro:IPR023430" /db_xref="SubtiList:BG10438" /db_xref="UniProtKB/Swiss-Prot:P22322" /translation="MKKSELDVNQYLIRTDLAVETKEAMANQQAVPTKEIKGFIEKER DHGGIKIRTVDVTKEGAELSGKKEGRYLTLEAQGIRENDSEMQEKVSAVFAEEFSAFL ENLNISKDASCLIVGLGNWNVTPDALGPMAVENLLVTRHLFKLQPENVQEGYRPVSAF APGVMGITGIETSDIIKGVIEQSKPDFVIAIDALAARAVERVNTTIQISDTGIHPGSG VGNKRKDLSKDTLGVPVIAIGVPTVVDAVTIASDTVDYILKHFGREMKDNRPSRSLVP AGMTFGKKKVLTEDDLPDQKQRQSFLGIVGTLQEDEKRQLIHEVLSPLGHNLMVTPKE VDSFIDDMANVLANGLNTALHEKVSQENKGSYNH*" gene complement(2500103..2501209) /gene="gpr" /locus_tag="BSU_25540" /old_locus_tag="BSU25540" promotor_-10 complement(2501237..2501248) /Source="Nicolas_upshift_promotors" /id="U1987" /multdbtbs="SigF,SigG" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=1139 /SigmaFactorBS="aatgtaaagtatttttcattgaaggttctctttttAGCATGA tttattcagcaaatGGCAACAATATAggtacttaatgtgaaggaggcccctgtatgaa a" /listShort="gpr, spoIIP, yqxA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2501244) /Source="Nicolas_upshifts" /id="U1987" /multdbtbs="SigF,SigG" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=1139 /SigmaFactorBS="aatgtaaagtatttttcattgaaggttctctttttAGCATGA tttattcagcaaatGGCAACAATATAggtacttaatgtgaaggaggcccctgtatgaa a" /listShort="gpr, spoIIP, yqxA" /GFF_Attribute="listLong" promotor_-35 complement(2501263..2501269) /Source="Nicolas_upshift_promotors" /id="U1987" /multdbtbs="SigF,SigG" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=1139 /SigmaFactorBS="aatgtaaagtatttttcattgaaggttctctttttAGCATGA tttattcagcaaatGGCAACAATATAggtacttaatgtgaaggaggcccctgtatgaa a" /listShort="gpr, spoIIP, yqxA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 2501308..2501311 /Source="Nicolas_upshift_promotors" /id="U1988" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.63936063936064" /psig=1 /xcortree=2636 /SigmaFactorBS="catgctaaaaagagaaccttcaatgaaaaatactttacattt atATTGcaatctaaaggtgtgTTTGATAGAATACAATTTGTtctattgtgaagaagat t" /listShort="S961, rpsT" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 2501324 /Source="Nicolas_upshifts" /id="U1988" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.63936063936064" /psig=1 /xcortree=2636 /SigmaFactorBS="catgctaaaaagagaaccttcaatgaaaaatactttacattt atATTGcaatctaaaggtgtgTTTGATAGAATACAATTTGTtctattgtgaagaagat t" /listShort="S961, rpsT" /GFF_Attribute="listLong" promotor_-10 2501327..2501346 /Source="Nicolas_upshift_promotors" /id="U1988" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.63936063936064" /psig=1 /xcortree=2636 /SigmaFactorBS="catgctaaaaagagaaccttcaatgaaaaatactttacattt atATTGcaatctaaaggtgtgTTTGATAGAATACAATTTGTtctattgtgaagaagat t" /listShort="S961, rpsT" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 2501338..2501412 /Source="Nicolas_S_feature" /locus_tag="new_2635740_2635814" /HighExp="HiTm, LPhT, UNK1, HiOs, dia5, aero, MG 15, SMM, Lbtran, MG 45" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S961" CDS 2501413..2501679 /gene="rpsT" /locus_tag="BSU_25550" /old_locus_tag="BSU25550" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:12682299, 16629673, 23002217" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12682299, 16629673, 23002217; Product type s: structure" /codon_start=1 /transl_table=11 /product="ribosomal protein S20 (BS20)" /protein_id="NP_390433.2" /db_xref="EnsemblGenomes-Gn:BSU25550" /db_xref="EnsemblGenomes-Tr:CAB14497" /db_xref="GOA:P21477" /db_xref="InterPro:IPR002583" /db_xref="InterPro:IPR036510" /db_xref="PDB:3J9W" /db_xref="PDB:5NJT" /db_xref="SubtiList:BG11643" /db_xref="UniProtKB/Swiss-Prot:P21477" /translation="MPNIKSAIKRTKTNNERRVHNATIKSAMRTAIKQVEASVANNEA DKAKTALTEAAKRIDKAVKTGLVHKNTAARYKSRLAKKVNGLSA*" gene 2501413..2501679 /gene="rpsT" /locus_tag="BSU_25550" /old_locus_tag="BSU25550" downshifts 2501668 /Source="Nicolas_upshifts" /id="D1321" /incds=0 /nref=244 /ntot=274 /MaxReadThrough="2.22204" /MaxDrop="8.54705" /score="33.3621187" /energy="-12.3" /TU="NA" /idTUdmin="U1988" /TUdmin=0 /isTUend="TRUE" CDS complement(2501694..2502737) /gene="holA" /locus_tag="BSU_25560" /old_locus_tag="BSU25560" /EC_number="2.7.7.7" /function="16.9: Replicate" /experiment="publication(s) with functional evidences, PMID:9434186, 11432857, 12060778, 12682299, 22333191, 23525462" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9434186, 11432857, 12060778, 12682299, 22333191, 23525462; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="DNA polymerase clamp loader delta subunit" /protein_id="NP_390434.1" /db_xref="EnsemblGenomes-Gn:BSU25560" /db_xref="EnsemblGenomes-Tr:CAB14498" /db_xref="GOA:P54459" /db_xref="InterPro:IPR005790" /db_xref="InterPro:IPR008921" /db_xref="InterPro:IPR010372" /db_xref="InterPro:IPR027417" /db_xref="PDB:3ZH9" /db_xref="SubtiList:BG11642" /db_xref="UniProtKB/Swiss-Prot:P54459" /translation="MVFDVWKSLKKGEVHPVYCLYGKETYLLQETVSRIRQTVVDQET KDFNLSVFDLEEDPLDQAIADAETFPFMGERRLVIVKNPYFLTGEKKKEKIEHNVSAL ESYIQSPAPYTVFVLLAPYEKLDERKKLTKALKKHAFMMEAKELNAKETTDFTVNLAK TEQKTIGTEAAEHLVLLVNGHLSSIFQEIQKLCTFIGDREEITLDDVKMLVARSLEQN IFELINKIVNRKRTESLQIFYDLLKQNEEPIKIMALISNQFRLILQTKYFAEQGYGQK QIASNLKVHPFRVKLAMDQARLFSEEELRLIIEQLAVMDYEMKTGKKDKQLLLELFLL QLLKRNEKNDPHY*" gene complement(2501694..2502737) /gene="holA" /locus_tag="BSU_25560" /old_locus_tag="BSU25560" downshifts complement(2501739) /Source="Nicolas_upshifts" /id="D1322" /incds=0 /nref=14 /ntot=198 /MaxReadThrough="1.76478" /MaxDrop="4.34213" /score="-1.12561483" /energy="-8.1" /TU="NA" /idTUdmin="U1989" /TUdmin=5 /isTUend="TRUE" promotor_-10 complement(2502766..2502785) /Source="Nicolas_upshift_promotors" /id="U1989" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.519480519480519" /psig="0.953046953046953" /xcortree=2159 /SigmaFactorBS="ttaatataaatggggaagcagcagtcaggcttcctCTTTAct attttgcaaacTCAATTTAGGATAGAAGGGGatgatgaaagagaggaagtcgtacaac a" /listShort="holA" /GFF_Attribute="listLong" /label="promotor_-10" CDS complement(2502777..2502926) /locus_tag="BSU_25565" /old_locus_tag="BSU25565" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_009513978.1" /translation="MKNLEAKVTFSVLVIIAFLQAVPGACEQAFNINGEAAVRLPLYY FANSI*" gene complement(2502777..2502926) /locus_tag="BSU_25565" /old_locus_tag="BSU25565" upshifts complement(2502778) /Source="Nicolas_upshifts" /id="U1989" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.519480519480519" /psig="0.953046953046953" /xcortree=2159 /SigmaFactorBS="ttaatataaatggggaagcagcagtcaggcttcctCTTTAct attttgcaaacTCAATTTAGGATAGAAGGGGatgatgaaagagaggaagtcgtacaac a" /listShort="holA" /GFF_Attribute="listLong" promotor_-35 complement(2502799..2502803) /Source="Nicolas_upshift_promotors" /id="U1989" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.519480519480519" /psig="0.953046953046953" /xcortree=2159 /SigmaFactorBS="ttaatataaatggggaagcagcagtcaggcttcctCTTTAct attttgcaaacTCAATTTAGGATAGAAGGGGatgatgaaagagaggaagtcgtacaac a" /listShort="holA" /GFF_Attribute="listLong" /label="promotor_-35" S_feature complement(2502801..2503140) /Source="Nicolas_S_feature" /locus_tag="new_2637203_2637542_c" /HighExp="S8, S6, S7, BT, S5, C30, Pyr, G/S, B36, GM 150" /AntisenseName="yqzM" /AntisenseCor="-2.0369593011890001E-2" /AntisenseRegPval="-0.1" /CDS_PredictionProba="NA" /TUshortSig="SigK, SigA" /TUshortPSig="1, 0.996" /TUlongSig="NA" /TUlongPSig="NA" /label="S962" downshifts complement(2502844) /Source="Nicolas_upshifts" /id="D1323" /incds=0 /nref=4 /ntot=37 /MaxReadThrough="5.04584" /MaxDrop="3.298" /score="-1.12561483" /energy="-8.1" /TU="U1991,U1995" /idTUdmin="U1992" /TUdmin=748 /isTUend="FALSE" promotor_-35 2502913..2502919 /Source="Nicolas_upshift_promotors" /id="U1990" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.405594405594406" /psig=1 /xcortree=421 /SigmaFactorBS="aaggcgataatcaccagaacagaaaacgttaccttagctTCT AGATttttcaaaacaatTCCATTATACTTAAGTCAGTcaggagggataaagttgaatg a" /listShort="yqzM" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2502933..2502952 /Source="Nicolas_upshift_promotors" /id="U1990" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.405594405594406" /psig=1 /xcortree=421 /SigmaFactorBS="aaggcgataatcaccagaacagaaaacgttaccttagctTCT AGATttttcaaaacaatTCCATTATACTTAAGTCAGTcaggagggataaagttgaatg a" /listShort="yqzM" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2502934 /Source="Nicolas_upshifts" /id="U1990" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.405594405594406" /psig=1 /xcortree=421 /SigmaFactorBS="aaggcgataatcaccagaacagaaaacgttaccttagctTCT AGATttttcaaaacaatTCCATTATACTTAAGTCAGTcaggagggataaagttgaatg a" /listShort="yqzM" /GFF_Attribute="listLong" CDS 2502967..2503101 /gene="yqzM" /locus_tag="BSU_25569" /old_locus_tag="BSU25569" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="YP_003097762.1" /db_xref="EnsemblGenomes-Gn:BSU25569" /db_xref="EnsemblGenomes-Tr:CAX52662" /db_xref="GOA:C0H453" /db_xref="InterPro:IPR025416" /db_xref="UniProtKB/Swiss-Prot:C0H453" /translation="MNDFEKNVQSKRNDAVDSAVGFVVSFGFFAFLFVMATVIHLVGS *" gene 2502967..2503101 /gene="yqzM" /locus_tag="BSU_25569" /old_locus_tag="BSU25569" downshifts 2503095 /Source="Nicolas_upshifts" /id="D1324" /incds=0 /nref=156 /ntot=250 /MaxReadThrough="3.51266" /MaxDrop="6.2258" /score="20.1810918" /energy="-12.1" /TU="U1990" /idTUdmin="U1990" /TUdmin="-465" /isTUend="FALSE" CDS complement(2503141..2505471) /gene="comEC" /locus_tag="BSU_25570" /old_locus_tag="BSU25570" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:12123453, 15661011, 16751195, 17630974, 21397556, 27318187" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12123453, 15661011, 16751195, 17630974, 21397556, 27318187; Product type cp : cell process" /codon_start=1 /transl_table=11 /product="DNA channel for uptake in competent cells" /protein_id="NP_390435.1" /db_xref="EnsemblGenomes-Gn:BSU25570" /db_xref="EnsemblGenomes-Tr:CAB14499" /db_xref="GOA:P39695" /db_xref="InterPro:IPR001279" /db_xref="InterPro:IPR004477" /db_xref="InterPro:IPR004797" /db_xref="InterPro:IPR025405" /db_xref="InterPro:IPR035681" /db_xref="InterPro:IPR036866" /db_xref="SubtiList:BG10482" /db_xref="UniProtKB/Swiss-Prot:P39695" /translation="MRNSRLLLPMAAASATAGITAAAYFPAIFLFILFLLIILIKTRH AFLIIVCFFSFILFFVLYAVTDSQNVSSYRQGTYQFKAVIDTIPKIDGDRMSMMVETP DKEKWAAAYRIQSAGEKEQLLYIEPGMSCELTGTLEEPNHATVPGAFDYNEYLYRQHI HWNYSVTSIQNCSEPENFKYKVLSLRKHIISFTNSLLPPDSTGIVQALTVGDRFYVED EVLTAYQKLGVVHLLAISGLHVGILTAGLFYIMIRLGITREKASILLLLFLPLYVMLT GAAPSVLRAALMSGVYLAGSLVKWRVRSATAICLSYIVLLLFNPYHLFEAGFQLSFAV SFSLILSSSIFQQVKTSLGQLTIVSLIAQLGSLPILLYHFHQFSIISVPMNMLMVPFY TFCILPGAVAGVLLLSLSASFGRLFFSWFDLLISWINRLITNIADVDVFTIMIAHPAP VLLFLFTVTIILLLMAIEKRSLSQLMVTGGICCTVMFLLFIYPCLSSEGEVDMIDIGQ GDSMFVGAPHQRGRVLIDTGGTLSYSSEPWREKQHPFSLGEKVLIPFLTAKGIKQLDA LILTHADQDHIGEAEILLKHHKVKRLVIPKGFVSEPKDEKVLQAAREEGVAIEEVKRG DVLQIKDLQFHVLSPEAPDPASKNNSSLVLWMETGGMSWILTGDLEKEGEQEVMNVFP NIKADVLKVGHHGSKGSTGEEFIQQLQPKTAIISAGKNNRYHHPHQKVLQLLQRHSIR VLRTDQNGTIQYRYKNRVGTFSVYPPYDTSDITETN*" gene complement(2503141..2505471) /gene="comEC" /locus_tag="BSU_25570" /old_locus_tag="BSU25570" promotor_-10 complement(2503158..2503177) /Source="Nicolas_upshift_promotors" /id="U1991" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1328 /SigmaFactorBS="aaacggaacgatccaatatagatacaaaaacagaGTTGGAAC CTtttctgtctatccTCCATATGATACATCAGATAtaacagagacgaactaaaaaaga c" /listShort="S962, holA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2503174) /Source="Nicolas_upshifts" /id="U1991" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1328 /SigmaFactorBS="aaacggaacgatccaatatagatacaaaaacagaGTTGGAAC CTtttctgtctatccTCCATATGATACATCAGATAtaacagagacgaactaaaaaaga c" /listShort="S962, holA" /GFF_Attribute="listLong" promotor_-35 complement(2503191..2503200) /Source="Nicolas_upshift_promotors" /id="U1991" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1328 /SigmaFactorBS="aaacggaacgatccaatatagatacaaaaacagaGTTGGAAC CTtttctgtctatccTCCATATGATACATCAGATAtaacagagacgaactaaaaaaga c" /listShort="S962, holA" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2505475..2506044) /gene="comEB" /locus_tag="BSU_25580" /old_locus_tag="BSU25580" /EC_number="3.5.4.12" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1c: Function from experimental evidences in the studied genus; PubMedId: 7768800, 26416910; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="dCMP deaminase associated to DNA transport (competence)" /protein_id="NP_390436.1" /db_xref="EnsemblGenomes-Gn:BSU25580" /db_xref="EnsemblGenomes-Tr:CAB14500" /db_xref="GOA:P32393" /db_xref="InterPro:IPR002125" /db_xref="InterPro:IPR013404" /db_xref="InterPro:IPR015517" /db_xref="InterPro:IPR016192" /db_xref="InterPro:IPR016193" /db_xref="InterPro:IPR016473" /db_xref="InterPro:IPR035105" /db_xref="SubtiList:BG10481" /db_xref="UniProtKB/Swiss-Prot:P32393" /translation="MERISWNQYFMAQSHLLALRSTCPRLSVGATIVRDKRMIAGGYN GSIAGGVHCADEGCLMIDDHCARTIHAEMNAILQCSKFGVPTDGAEIYVTHYPCIQCC KSIIQAGIKTVYYAEDYKTHPYAQELFEQAGVTVEQVELDEMIVDLKNREKLSFVAGL IGKLADAGLAEEELKKIHEQANTLFTSYV*" gene complement(2505475..2506044) /gene="comEB" /locus_tag="BSU_25580" /old_locus_tag="BSU25580" promotor_-10 complement(2506071..2506090) /Source="Nicolas_upshift_promotors" /id="U1992" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.903096903096903" /psig=1 /xcortree=1881 /SigmaFactorBS="gaaaataaagtcttccattacagtaaagtGATTTGACggtca tgcattatgATAGGTAAACTAAAGGTCAGgcaacacaacatttggagggaacaacgtg g" /listShort="comEB, comEC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2506081) /Source="Nicolas_upshifts" /id="U1992" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.903096903096903" /psig=1 /xcortree=1881 /SigmaFactorBS="gaaaataaagtcttccattacagtaaagtGATTTGACggtca tgcattatgATAGGTAAACTAAAGGTCAGgcaacacaacatttggagggaacaacgtg g" /listShort="comEB, comEC" /GFF_Attribute="listLong" promotor_-35 complement(2506105..2506112) /Source="Nicolas_upshift_promotors" /id="U1992" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.903096903096903" /psig=1 /xcortree=1881 /SigmaFactorBS="gaaaataaagtcttccattacagtaaagtGATTTGACggtca tgcattatgATAGGTAAACTAAAGGTCAGgcaacacaacatttggagggaacaacgtg g" /listShort="comEB, comEC" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2506111..2506728) /gene="comEA" /locus_tag="BSU_25590" /old_locus_tag="BSU25590" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:16751195, 21278288, 22398145, 25727469" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16751195, 21278288, 22398145, 25727469; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="membrane bound high-affinity DNA-binding receptor" /protein_id="NP_390437.1" /db_xref="EnsemblGenomes-Gn:BSU25590" /db_xref="EnsemblGenomes-Tr:CAB14501" /db_xref="GOA:P39694" /db_xref="InterPro:IPR003583" /db_xref="InterPro:IPR004509" /db_xref="InterPro:IPR004787" /db_xref="InterPro:IPR010994" /db_xref="InterPro:IPR019554" /db_xref="SubtiList:BG10480" /db_xref="UniProtKB/Swiss-Prot:P39694" /translation="MNWLNQHKKAIILAASAAVFTAIMIFLATGKNKEPVKQAVPTET ENTVVKQEANNDESNETIVIDIKGAVQHPGVYEMRTGDRVSQAIEKAGGTSEQADEAQ VNLAEILQDGTVVYIPKKGEETAVQQGGGGSVQSDGGKGALVNINTATLEELQGISGV GPSKAEAIIAYREENGRFQTIEDITKVSGIGEKSFEKIKSSITVK*" gene complement(2506111..2506728) /gene="comEA" /locus_tag="BSU_25590" /old_locus_tag="BSU25590" promotor_-35 2506749..2506754 /Source="Nicolas_upshift_promotors" /id="U1993" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1103 /SigmaFactorBS="ttatgctgattcaaccaattcatcgtgcatgttccccgcttt cGTCATAttttattttcataacACATATGGTTTAGAGGATAatagctcaaaggagggg a" /listShort="comER" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 2506766 /Source="Nicolas_upshifts" /id="U1993" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1103 /SigmaFactorBS="ttatgctgattcaaccaattcatcgtgcatgttccccgcttt cGTCATAttttattttcataacACATATGGTTTAGAGGATAatagctcaaaggagggg a" /listShort="comER" /GFF_Attribute="listLong" promotor_-10 2506770..2506788 /Source="Nicolas_upshift_promotors" /id="U1993" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1103 /SigmaFactorBS="ttatgctgattcaaccaattcatcgtgcatgttccccgcttt cGTCATAttttattttcataacACATATGGTTTAGAGGATAatagctcaaaggagggg a" /listShort="comER" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-10 complement(2506789..2506803) /Source="Nicolas_upshift_promotors" /id="U1994" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.999000999001" /psig="0.000999000999001" /xcortree=681 /SigmaFactorBS="tcgtacccatatttcctgtgccgataaagcctatcTTCAAtg gtttccCCTCCTTTGAGCTATtatcctctaaaccatatgtgttatgaaaataaaatat g" /listShort="comEA, comEB, comEC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2506791) /Source="Nicolas_upshifts" /id="U1994" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.999000999001" /psig="0.000999000999001" /xcortree=681 /SigmaFactorBS="tcgtacccatatttcctgtgccgataaagcctatcTTCAAtg gtttccCCTCCTTTGAGCTATtatcctctaaaccatatgtgttatgaaaataaaatat g" /listShort="comEA, comEB, comEC" /GFF_Attribute="listLong" S_feature complement(2506793..2507640) /Source="Nicolas_S_feature" /locus_tag="new_2641195_2642042_c" /HighExp="C30, T0.30H, T-2.40H, GM 150, T1.30H, T-0.40H, T-1.10H, T-1.40H, T1.0H, T0.0H" /AntisenseName="comER" /AntisenseCor="-8.2389039371154299E-2" /AntisenseRegPval="-0.7" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.996" /TUlongSig="NA" /TUlongPSig="NA" /label="S963" promotor_-35 complement(2506812..2506816) /Source="Nicolas_upshift_promotors" /id="U1994" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.999000999001" /psig="0.000999000999001" /xcortree=681 /SigmaFactorBS="tcgtacccatatttcctgtgccgataaagcctatcTTCAAtg gtttccCCTCCTTTGAGCTATtatcctctaaaccatatgtgttatgaaaataaaatat g" /listShort="comEA, comEB, comEC" /GFF_Attribute="listLong" /label="promotor_-35" CDS 2506812..2507633 /gene="comER" /locus_tag="BSU_25600" /old_locus_tag="BSU25600" /EC_number="1.5.1.2" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 7968523, 11418582, 27446060, 28824574; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative pyrroline-5'-carboxylate reductase" /protein_id="NP_390438.1" /db_xref="EnsemblGenomes-Gn:BSU25600" /db_xref="EnsemblGenomes-Tr:CAB14502" /db_xref="GOA:P39696" /db_xref="InterPro:IPR000304" /db_xref="InterPro:IPR008927" /db_xref="InterPro:IPR028939" /db_xref="InterPro:IPR029036" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG10479" /db_xref="UniProtKB/Swiss-Prot:P39696" /translation="MKIGFIGTGNMGTILIESFIESKAADPSNMTITNRTIEKALHIK NRYNSINVTESLEKLVSENEMIFICVKPLDIYPLLARALPYLRKDHILISITSPVQTE QLEQYVPCQVARVIPSITNRALAGVSLVTFGTSCGESAKAKINELMQHISHPLQIESD ITRVASDIVSCGPAFMSYLIQRFIDAAVSETSVSKQDAILMCKEMLVGMGKLLETELY TLPALQEKVCVKGGVTGEGIKALESGVQDMFHRVFQNTHMKYEEDISAVKKQFHV*" gene 2506812..2507633 /gene="comER" /locus_tag="BSU_25600" /old_locus_tag="BSU25600" promotor_-10 complement(2507628..2507647) /Source="Nicolas_upshift_promotors" /id="U1995" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.95104895104895" /psig="0.996003996003996" /xcortree=2968 /SigmaFactorBS="taaaacgatggttttttaaaatgcttttttatgCTTTTGCAg tacagacgaacgTATGACATACTCGTCTACACatgaaactgctttttcactgcggaaa t" /listShort="S963, comEA, comEB, comEC, S962, holA" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 2507634..2507714 /Source="Nicolas_S_feature" /locus_tag="new_2642036_2642116" /HighExp="S4, S5, S3, S6, S7, B36, Pyr, G/S, S8, BT" /AntisenseName="yqeM" /AntisenseCor="-0.52267300854840604" /AntisenseRegPval="-19.5" /CDS_PredictionProba="NA" /TUshortSig="NA" /TUshortPSig="NA" /TUlongSig="NA" /TUlongPSig="NA" /label="S964" upshifts complement(2507641) /Source="Nicolas_upshifts" /id="U1995" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.95104895104895" /psig="0.996003996003996" /xcortree=2968 /SigmaFactorBS="taaaacgatggttttttaaaatgcttttttatgCTTTTGCAg tacagacgaacgTATGACATACTCGTCTACACatgaaactgctttttcactgcggaaa t" /listShort="S963, comEA, comEB, comEC, S962, holA" /GFF_Attribute="listLong" promotor_-35 complement(2507661..2507668) /Source="Nicolas_upshift_promotors" /id="U1995" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.95104895104895" /psig="0.996003996003996" /xcortree=2968 /SigmaFactorBS="taaaacgatggttttttaaaatgcttttttatgCTTTTGCAg tacagacgaacgTATGACATACTCGTCTACACatgaaactgctttttcactgcggaaa t" /listShort="S963, comEA, comEB, comEC, S962, holA" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 2507674 /Source="Nicolas_upshifts" /id="D1325" /incds=0 /nref=45 /ntot=64 /MaxReadThrough="2.4803" /MaxDrop="5.1403" /score="7.09525061" /energy="-10.5" /TU="NA" /idTUdmin="U1993" /TUdmin=0 /isTUend="TRUE" CDS complement(2507699..2508442) /gene="yqeM" /locus_tag="BSU_25610" /old_locus_tag="BSU25610" /EC_number="2.1.1.-" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative methyltransferase" /protein_id="NP_390439.1" /db_xref="EnsemblGenomes-Gn:BSU25610" /db_xref="EnsemblGenomes-Tr:CAB14503" /db_xref="GOA:P54458" /db_xref="InterPro:IPR029063" /db_xref="SubtiList:BG11641" /db_xref="UniProtKB/Swiss-Prot:P54458" /translation="MIYQGFASVYDELMSHAPYDQWTKWIEASLPEKGRILDLACGTG EISIRLAEKGFEVTGIDLSEEMLSFAQQKVSSSQPILFLQQDMREITGFDGQFDAVVI CCDSLNYLKTKNDVIETFKSVFRVLKPEGILLFDVHSSFKIAEVFPDSTFADQDEDIS YIWQSFAGSDELSVIHDMSFFVWNGEAYDRFDETHEQRTFPVEEYEEMLKNCGFQLHR VTADFTDTEPSAQSERLFFKAQKSKTIVS*" gene complement(2507699..2508442) /gene="yqeM" /locus_tag="BSU_25610" /old_locus_tag="BSU25610" downshifts complement(2507729) /Source="Nicolas_upshifts" /id="D1326" /incds=0 /nref=144 /ntot=230 /MaxReadThrough="1.41467" /MaxDrop="5.51802" /score="7.9251293" /energy="-10.5" /TU="NA" /idTUdmin="U1996" /TUdmin="-1" /isTUend="TRUE" CDS complement(2508439..2508795) /gene="rsfS" /locus_tag="BSU_25620" /old_locus_tag="BSU25620" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 15044829, 16980477, 22238375, 22238376, 22829778, 26299947; Product type f : factor" /codon_start=1 /transl_table=11 /product="ribosomal silencing factor" /protein_id="NP_390440.1" /db_xref="EnsemblGenomes-Gn:BSU25620" /db_xref="EnsemblGenomes-Tr:CAB14504" /db_xref="GOA:P54457" /db_xref="InterPro:IPR004394" /db_xref="SubtiList:BG11640" /db_xref="UniProtKB/Swiss-Prot:P54457" /translation="MNQKSILKIAAAACDDKRAEDILALDMEGISLVADYFLICHGNS DKQVQAIAREIKDQADENGIQVKKMEGFDEARWVLVDLGDVVVHVFHKDERSYYNLEK LWGDAPLADLDFGMNQ*" gene complement(2508439..2508795) /gene="rsfS" /locus_tag="BSU_25620" /old_locus_tag="BSU25620" CDS complement(2508813..2509373) /gene="yqeK" /locus_tag="BSU_25630" /old_locus_tag="BSU25630" /function="16.2: Construct biomass (Anabolism)" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15175311, 22333191; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative hydrolase" /protein_id="NP_390441.1" /db_xref="EnsemblGenomes-Gn:BSU25630" /db_xref="EnsemblGenomes-Tr:CAB14505" /db_xref="InterPro:IPR003607" /db_xref="InterPro:IPR005249" /db_xref="InterPro:IPR006674" /db_xref="SubtiList:BG11639" /db_xref="UniProtKB/Swiss-Prot:P54456" /translation="MNREEALACVKQQLTEHRYIHTVGVMNTAIELAERFGADSKKAE IAAIFHDYAKFRPKEEMKQIIAREKMPAHLLDHNPELWHAPVGAYLVQREAGVQDEDI LDAIRYHTSGRPGMTLLEKVIYVADYIEPNRAFPGVDEVRKLAETDLNQALIQSIKNT MVFLMKKNQPVFPDTFLTYNWLVSGS*" gene complement(2508813..2509373) /gene="yqeK" /locus_tag="BSU_25630" /old_locus_tag="BSU25630" CDS complement(2509363..2509932) /gene="nadD" /locus_tag="BSU_25640" /old_locus_tag="BSU25640" /EC_number="2.7.7.18" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 11704676, 12682299, 19716475, 23204464, 25631047; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="nicotinate-nucleotide adenylyltransferase" /protein_id="NP_390442.1" /db_xref="EnsemblGenomes-Gn:BSU25640" /db_xref="EnsemblGenomes-Tr:CAB14506" /db_xref="GOA:P54455" /db_xref="InterPro:IPR004821" /db_xref="InterPro:IPR005248" /db_xref="InterPro:IPR014729" /db_xref="PDB:1KAM" /db_xref="PDB:1KAQ" /db_xref="SubtiList:BG11638" /db_xref="UniProtKB/Swiss-Prot:P54455" /translation="MKKIGIFGGTFDPPHNGHLLMANEVLYQAGLDEIWFMPNQIPPH KQNEDYTDSFHRVEMLKLAIQSNPSFKLELVEMEREGPSYTFDTVSLLKQRYPNDQLF FIIGADMIEYLPKWYKLDELLNLIQFIGVKRPGFHVETPYPLLFADVPEFEVSSTMIR ERFKSKKPTDYLIPDKVKKYVEENGLYES*" gene complement(2509363..2509932) /gene="nadD" /locus_tag="BSU_25640" /old_locus_tag="BSU25640" CDS complement(2509944..2510234) /gene="yqeI" /locus_tag="BSU_25650" /old_locus_tag="BSU25650" /experiment="publication(s) with functional evidences, PMID:12682299, 16014871, 17005971, 17105995" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12682299, 16014871, 17005971, 17105995; Product type f: factor" /codon_start=1 /transl_table=11 /product="50S RNA-binding protein" /protein_id="NP_390443.1" /db_xref="EnsemblGenomes-Gn:BSU25650" /db_xref="EnsemblGenomes-Tr:CAB14507" /db_xref="GOA:P54454" /db_xref="InterPro:IPR001890" /db_xref="InterPro:IPR017924" /db_xref="InterPro:IPR035920" /db_xref="SubtiList:BG11637" /db_xref="UniProtKB/Swiss-Prot:P54454" /translation="MLTGKQKRFLRSKAHHLTPIFQVGKGGVNDNMIKQIAEALEARE LIKVSVLQNCEEDKNDVAEALVKGSRSQLVQTIGNTIVLYKESKENKQIELP*" gene complement(2509944..2510234) /gene="yqeI" /locus_tag="BSU_25650" /old_locus_tag="BSU25650" CDS complement(2510228..2511070) /gene="aroE" /locus_tag="BSU_25660" /old_locus_tag="BSU25660" /EC_number="1.1.1.25" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 2104604, 12906820, 22938038; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="shikimate 5-dehydrogenase" /protein_id="NP_390444.2" /db_xref="EnsemblGenomes-Gn:BSU25660" /db_xref="EnsemblGenomes-Tr:CAB14508" /db_xref="GOA:P54374" /db_xref="InterPro:IPR006151" /db_xref="InterPro:IPR011342" /db_xref="InterPro:IPR013708" /db_xref="InterPro:IPR022893" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG11522" /db_xref="UniProtKB/Swiss-Prot:P54374" /translation="MKKLYGVIGNPIGHSMSPDIHNASLKDLGLDGHYHAFKVEENDL EDAVKGIRALGVQGINVTVPHKVSIMDYLDHIDESAKVLGAVNTVRREGDKLVGYNTD GEGFVKSLMKVLDKPISELSFLMIGAGGAARAIFTTIVRNTPKKFDICNRTLEKAKRL TEATPSFHNKEVLSIKEAEERLEQYDVIIHTTSVGMYPNVDDVPLSLQRAASSAVVCD IVYNPIQTALLKEASQKGLKTLDGVGMFVEQAALSFQLWTGQEPNIEKMRSIVIGKLG GTEC*" gene complement(2510228..2511070) /gene="aroE" /locus_tag="BSU_25660" /old_locus_tag="BSU25660" downshifts 2511062 /Source="Nicolas_upshifts" /id="D1327" /incds=0 /nref=2 /ntot=118 /MaxReadThrough="0.240279999999999" /MaxDrop="3.04009" /score="0.0642154872" /energy="-17" /TU="NA" /idTUdmin="U1993" /TUdmin=3388 /isTUend="FALSE" CDS complement(2511088..2512188) /gene="rgpH" /locus_tag="BSU_25670" /old_locus_tag="BSU25670" /function="16.6: Maintain" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:12427945, 12682299, 17237168, 17895579, 18801747, 19540197, 20376346, 22750478" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12427945, 12682299, 17237168, 17895579, 18801747, 19540197, 20376346, 22750478; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="potassium-dependent GTPase involved in ribosome 30S assembly" /protein_id="NP_390445.1" /db_xref="EnsemblGenomes-Gn:BSU25670" /db_xref="EnsemblGenomes-Tr:CAB14509" /db_xref="GOA:P54453" /db_xref="InterPro:IPR006073" /db_xref="InterPro:IPR019988" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR030378" /db_xref="SubtiList:BG11636" /db_xref="UniProtKB/Swiss-Prot:P54453" /translation="MEKVVCIGCGVTIQTEDKTGLGYAPPASLTKENVICQRCFRLKN YNEIQDVSLTDDDFLNILHGIGETDSLVVKIVDIFDFNGSWINGLQRLVGGNPILLVG NKADILPKSLKRERLIQWMKREAKELGLKPVDVFLVSAGRGQGIREVIDAIEHYRNGK DVYVVGCTNVGKSTFINRIIKEVSGEEDIITTSQFPGTTLDAIEIPLDDGSSLYDTPG IINNHQMAHYVNKKDLKILSPKKELKPRTFQLNDQQTLYFGGLARFDYVSGERSPFIC YMPNELMIHRTKLENADALYEKHAGELLTPPGKDEMDEFPELVAHTFTIKDKKTDIVF SGLGWVTVHDADKKVTAYAPKGVHVFVRRSLI*" gene complement(2511088..2512188) /gene="rgpH" /locus_tag="BSU_25670" /old_locus_tag="BSU25670" CDS complement(2512192..2512710) /gene="yqeG" /locus_tag="BSU_25680" /old_locus_tag="BSU25680" /EC_number="3.1.3.-" /experiment="publication(s) with functional evidences, PMID:27784292" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 27784292; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="phosphatase (active on GMP and Glc-6-P)" /protein_id="NP_390446.1" /db_xref="EnsemblGenomes-Gn:BSU25680" /db_xref="EnsemblGenomes-Tr:CAB14510" /db_xref="GOA:P54452" /db_xref="InterPro:IPR006356" /db_xref="InterPro:IPR006439" /db_xref="InterPro:IPR006549" /db_xref="InterPro:IPR010021" /db_xref="InterPro:IPR023214" /db_xref="InterPro:IPR036412" /db_xref="SubtiList:BG11635" /db_xref="UniProtKB/Swiss-Prot:P54452" /translation="MLKKFFLPDEFVKNIFHITPEKLKERNVKGIITDLDNTLVEWDR PNATPRLIEWFEEMKEHGIKVTIVSNNNERRVKLFSEPLGIPFIYKARKPMGKAFNRA VRNMELKKEDCVVIGDQLLTDVLGGNRNGYHTILVVPVASSDGFITRFNRQVERRILS ALKRKGHIQWEE*" gene complement(2512192..2512710) /gene="yqeG" /locus_tag="BSU_25680" /old_locus_tag="BSU25680" promotor_-10 complement(2512620..2512637) /Source="Nicolas_upshift_promotors" /id="U1996" /multdbtbs="-" /comp="M10" /sig="Sig-" /pcomp="0.415584415584416" /psig="0.415584415584416" /xcortree=2452 /SigmaFactorBS="ttttacctgacgagtttgtaaaaaatatttttcatattACAC ctgagaaattaaaggAACGAAATGTAAAAGGAAttattactgacctggataatacgct t" /listShort="yqeH, aroD, yqeI, nadD, yqeK, yqeL, yqeM" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2512634) /Source="Nicolas_upshifts" /id="U1996" /multdbtbs="-" /comp="M10" /sig="Sig-" /pcomp="0.415584415584416" /psig="0.415584415584416" /xcortree=2452 /SigmaFactorBS="ttttacctgacgagtttgtaaaaaatatttttcatattACAC ctgagaaattaaaggAACGAAATGTAAAAGGAAttattactgacctggataatacgct t" /listShort="yqeH, aroD, yqeI, nadD, yqeK, yqeL, yqeM" /GFF_Attribute="listLong" promotor_-35 complement(2512653..2512656) /Source="Nicolas_upshift_promotors" /id="U1996" /multdbtbs="-" /comp="M10" /sig="Sig-" /pcomp="0.415584415584416" /psig="0.415584415584416" /xcortree=2452 /SigmaFactorBS="ttttacctgacgagtttgtaaaaaatatttttcatattACAC ctgagaaattaaaggAACGAAATGTAAAAGGAAttattactgacctggataatacgct t" /listShort="yqeH, aroD, yqeI, nadD, yqeK, yqeL, yqeM" /GFF_Attribute="listLong" /label="promotor_-35" S_feature complement(2512711..2513272) /Source="Nicolas_S_feature" /locus_tag="new_2647113_2647674_c" /HighExp="G135, G180, G150, Paraq, Oxctl, C30, Heat, HPh, BMM, LPh" /AntisenseName="sda" /AntisenseCor="-8.6107693225382295E-2" /AntisenseRegPval="-0.8" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S965" downshifts complement(2512744) /Source="Nicolas_upshifts" /id="D1328" /incds=0 /nref=1 /ntot=1 /MaxReadThrough="6.83118" /MaxDrop="5.26138" /score="9.20556883" /energy="-8.6" /TU="U1998" /idTUdmin="U1999" /TUdmin=616 /isTUend="FALSE" promotor_-35 2512935..2512942 /Source="Nicolas_upshift_promotors" /id="U1997" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.98101898101898" /psig=1 /xcortree=2945 /SigmaFactorBS="tactcacaagttatccactttttggtgtggataacagaacga TTGTTCTTatatgcatttCATGGTAGATTAAAGATAACttcaacctcagatgaatgca a" /listShort="S966, sda, S967, S969" /GFF_Attribute="listLong" /label="promotor_-35" S_feature 2512953..2513053 /Source="Nicolas_S_feature" /locus_tag="new_2647355_2647455" /HighExp="T3.0H, T-0.40H, MG 150, T5.0H, T-1.40H, T4.0H, T2.30H, T0.0H, T3.30H, HiOs" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S966" promotor_-10 2512953..2512972 /Source="Nicolas_upshift_promotors" /id="U1997" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.98101898101898" /psig=1 /xcortree=2945 /SigmaFactorBS="tactcacaagttatccactttttggtgtggataacagaacga TTGTTCTTatatgcatttCATGGTAGATTAAAGATAACttcaacctcagatgaatgca a" /listShort="S966, sda, S967, S969" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2512953 /Source="Nicolas_upshifts" /id="U1997" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.98101898101898" /psig=1 /xcortree=2945 /SigmaFactorBS="tactcacaagttatccactttttggtgtggataacagaacga TTGTTCTTatatgcatttCATGGTAGATTAAAGATAACttcaacctcagatgaatgca a" /listShort="S966, sda, S967, S969" /GFF_Attribute="listLong" misc_RNA complement(2513003..2513261) /gene="sdaM" /locus_tag="BSU_misc_RNA_80" /product="antisense RNA" /experiment="publication(s) with functional evidences, PMID:20525796" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 20525796; Product type n: RNA" gene complement(2513003..2513261) /gene="sdaM" /locus_tag="BSU_misc_RNA_80" CDS 2513054..2513212 /gene="sda" /locus_tag="BSU_25690" /old_locus_tag="BSU25690" /function="16.3: Control" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:15023339, 16796683, 19040634, 22720735, 28752667" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15023339, 16796683, 19040634, 22720735, 28752667; Product type f: factor" /codon_start=1 /transl_table=11 /product="check point factor coupling initiation of sporulation and replication initiation" /protein_id="YP_054588.1" /db_xref="EnsemblGenomes-Gn:BSU25690" /db_xref="EnsemblGenomes-Tr:CAE01463" /db_xref="GOA:Q7WY62" /db_xref="InterPro:IPR015064" /db_xref="InterPro:IPR036916" /db_xref="PDB:1PV0" /db_xref="PDB:3FYR" /db_xref="SubtiList:BG14183" /db_xref="UniProtKB/Swiss-Prot:Q7WY62" /translation="MNWVPSMRKLSDELLIESYFKATEMNLNRDFIELIENEIKRRSL GHIISVSS*" gene 2513054..2513212 /gene="sda" /locus_tag="BSU_25690" /old_locus_tag="BSU25690" S_feature 2513213..2513459 /Source="Nicolas_S_feature" /locus_tag="new_2647615_2647861" /HighExp="Cold, T-0.40H, MG 150, T5.0H, T4.0H, C30, T2.30H, M9-tran, S2, GM 150" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S967" promotor_-10 complement(2513260..2513279) /Source="Nicolas_upshift_promotors" /id="U1998" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.509490509490509" /psig="0.999000999001" /xcortree=2592 /SigmaFactorBS="cctctttttaggggtgttttttgctgaaaataGTAGTaaagc gcgcagccaaAGTGATATAATATCAGTCATctgagtaaaaaaaggaaatacgcccgga a" /listShort="S965, yqeG, yqeH, aroD, yqeI, nadD, yqeK, yqeL, yqeM" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2513271) /Source="Nicolas_upshifts" /id="U1998" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.509490509490509" /psig="0.999000999001" /xcortree=2592 /SigmaFactorBS="cctctttttaggggtgttttttgctgaaaataGTAGTaaagc gcgcagccaaAGTGATATAATATCAGTCATctgagtaaaaaaaggaaatacgcccgga a" /listShort="S965, yqeG, yqeH, aroD, yqeI, nadD, yqeK, yqeL, yqeM" /GFF_Attribute="listLong" promotor_-35 complement(2513295..2513299) /Source="Nicolas_upshift_promotors" /id="U1998" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.509490509490509" /psig="0.999000999001" /xcortree=2592 /SigmaFactorBS="cctctttttaggggtgttttttgctgaaaataGTAGTaaagc gcgcagccaaAGTGATATAATATCAGTCATctgagtaaaaaaaggaaatacgcccgga a" /listShort="S965, yqeG, yqeH, aroD, yqeI, nadD, yqeK, yqeL, yqeM" /GFF_Attribute="listLong" /label="promotor_-35" S_feature complement(2513323..2513470) /Source="Nicolas_S_feature" /locus_tag="new_2647725_2647872_c" /HighExp="S8, S7, S6, Etha, LBGstat, T0.30H, Salt, BT, LPhT, C30" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.99948400000000004" /TUshortSig="SigK, SigA, SigB" /TUshortPSig="1, 1, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S968" downshifts complement(2513360) /Source="Nicolas_upshifts" /id="D1329" /incds=0 /nref=12 /ntot=92 /MaxReadThrough="2.70676" /MaxDrop="4.386" /score="9.20556883" /energy="-8.6" /TU="NA" /idTUdmin="U1999" /TUdmin=0 /isTUend="TRUE" downshifts 2513416 /Source="Nicolas_upshifts" /id="D1330" /incds=0 /nref=1 /ntot=126 /MaxReadThrough="5.36291" /MaxDrop="2.1106" /score="10.3636587" /energy="-6.2" /TU="U1997" /idTUdmin="U1997" /TUdmin="-1056" /isTUend="FALSE" S_feature 2513461..2514514 /Source="Nicolas_S_feature" /locus_tag="new_2647863_2648916" /HighExp="T-0.40H, Cold, M40t90, T0.0H, C30, Glucon, S2, T1.30H, T2.30H, T2.0H" /AntisenseName="yqeF" /AntisenseCor="-0.39616310996746001" /AntisenseRegPval="-10.8" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S969" promotor_-10 complement(2513465..2513484) /Source="Nicolas_upshift_promotors" /id="U1999" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1228 /SigmaFactorBS="cctgcagcgttgagccggacaaccGCCTAGTCCGatttattt ctccTACATAGGCTGTTATAAAACcttattaaggaggcgcttcacatgtatggcgcag g" /listShort="S968" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2513470) /Source="Nicolas_upshifts" /id="U1999" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1228 /SigmaFactorBS="cctgcagcgttgagccggacaaccGCCTAGTCCGatttattt ctccTACATAGGCTGTTATAAAACcttattaaggaggcgcttcacatgtatggcgcag g" /listShort="S968" /GFF_Attribute="listLong" promotor_-35 complement(2513497..2513506) /Source="Nicolas_upshift_promotors" /id="U1999" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1228 /SigmaFactorBS="cctgcagcgttgagccggacaaccGCCTAGTCCGatttattt ctccTACATAGGCTGTTATAAAACcttattaaggaggcgcttcacatgtatggcgcag g" /listShort="S968" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2513518..2514249) /gene="yqeF" /locus_tag="BSU_25700" /old_locus_tag="BSU25700" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative lipoprotein; putative esterase" /protein_id="NP_390447.1" /db_xref="EnsemblGenomes-Gn:BSU25700" /db_xref="EnsemblGenomes-Tr:CAB14511" /db_xref="GOA:P54451" /db_xref="InterPro:IPR013830" /db_xref="InterPro:IPR036514" /db_xref="SubtiList:BG11634" /db_xref="UniProtKB/Swiss-Prot:P54451" /translation="MKHFIILFLLLFVTAGCEGRGYEDVVAFGDSNTRGSNWDYRDYP KAQQWVNILKTAERGNLDILNAGIGGQTTEDARLRFQTDVLDQKPKYLFIMFGTNDAA ILTEGKPRVSKQRFRENLVYFIEESRKHGIKPILMTCIPIIEGNGKHHLFYYSRYQAA AFEPKGGARKWHNSYNDITRDVSKRLDVPLVDNWKHFIEADGGKATDEALIQSGLIDP SGNHMTPKGARIVYEGIQDGQILQR*" gene complement(2513518..2514249) /gene="yqeF" /locus_tag="BSU_25700" /old_locus_tag="BSU25700" promotor_-10 complement(2514268..2514287) /Source="Nicolas_upshift_promotors" /id="U2000" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.380619380619381" /psig=1 /xcortree=2739 /SigmaFactorBS="taactataggaaaaaacagtgatagcgaaaaactcttCATTG AAcgaagagaaacagAGGTATAACATTAAAGTGAGgcttttgggggtgtaaagatgaa a" /listShort="yqeF, S968" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2514284) /Source="Nicolas_upshifts" /id="U2000" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.380619380619381" /psig=1 /xcortree=2739 /SigmaFactorBS="taactataggaaaaaacagtgatagcgaaaaactcttCATTG AAcgaagagaaacagAGGTATAACATTAAAGTGAGgcttttgggggtgtaaagatgaa a" /listShort="yqeF, S968" /GFF_Attribute="listLong" S_feature complement(2514286..2514394) /Source="Nicolas_S_feature" /locus_tag="new_2648688_2648796_c" /HighExp="Etha, Salt, Gly, S8, C30, S7, LPhT, Sw, Heat, HiTm" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigB" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S970" promotor_-35 complement(2514301..2514307) /Source="Nicolas_upshift_promotors" /id="U2000" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.380619380619381" /psig=1 /xcortree=2739 /SigmaFactorBS="taactataggaaaaaacagtgatagcgaaaaactcttCATTG AAcgaagagaaacagAGGTATAACATTAAAGTGAGgcttttgggggtgtaaagatgaa a" /listShort="yqeF, S968" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(2514395..2514413) /Source="Nicolas_upshift_promotors" /id="U2001" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=162 /SigmaFactorBS="tttccagtgcggattcaggttattttcttttctttggtttgt gTGTTTTtcagattggaaagaAGGGAATTTTAAAAAATCAtcagctgcgccgcaatga a" /listShort="S970, yqeF, S968" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2514416) /Source="Nicolas_upshifts" /id="U2001" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=162 /SigmaFactorBS="tttccagtgcggattcaggttattttcttttctttggtttgt gTGTTTTtcagattggaaagaAGGGAATTTTAAAAAATCAtcagctgcgccgcaatga a" /listShort="S970, yqeF, S968" /GFF_Attribute="listLong" promotor_-35 complement(2514428..2514433) /Source="Nicolas_upshift_promotors" /id="U2001" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=162 /SigmaFactorBS="tttccagtgcggattcaggttattttcttttctttggtttgt gTGTTTTtcagattggaaagaAGGGAATTTTAAAAAATCAtcagctgcgccgcaatga a" /listShort="S970, yqeF, S968" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2514501..2515253) /gene="cwlH" /locus_tag="BSU_25710" /old_locus_tag="BSU25710" /EC_number="3.5.1.28" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:10515909, 10974124, 15687192" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10515909, 10974124, 15687192; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="N-acetylmuramoyl-L-alanine amidase" /protein_id="NP_390448.1" /db_xref="EnsemblGenomes-Gn:BSU25710" /db_xref="EnsemblGenomes-Tr:CAB14512" /db_xref="GOA:P54450" /db_xref="InterPro:IPR002477" /db_xref="InterPro:IPR002502" /db_xref="InterPro:IPR036365" /db_xref="InterPro:IPR036366" /db_xref="InterPro:IPR036505" /db_xref="SubtiList:BG11633" /db_xref="UniProtKB/Swiss-Prot:P54450" /translation="MVTIKKDFIPVSNDNRPGYAMAPAYITVHNTANTAKGADAKMHA KFVKNPNTSESWHFTVDDSVIYQHLPIDENGWHAGDGTNGTGNRKSIGIEICENADGD FEKATSNAQWLIRKLMKENNIPLNRVVPHKKWSGKECPRKLLDHWNSFLNGISSSDTP PKETSPSYPLPSGVIKLTSPYRKGTNILQLQKALAVLHFYPDKGAKNNGIDGVYGPKT ANAVKRFQLMNGLTADGIYGPKTKAKLKSKLK*" gene complement(2514501..2515253) /gene="cwlH" /locus_tag="BSU_25710" /old_locus_tag="BSU25710" downshifts complement(2514504) /Source="Nicolas_upshifts" /id="D1331" /incds=0 /nref=4 /ntot=10 /MaxReadThrough="1.29819" /MaxDrop="4.65121" /score="4.6304411" /energy="-10.7" /TU="NA" /idTUdmin="U2003" /TUdmin=0 /isTUend="TRUE" promotor_-35 2514632..2514638 /Source="Nicolas_upshift_promotors" /id="U2002" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=171 /SigmaFactorBS="ctgttttcggtccgtaaactccatctatgccatTGTTTTTgg ctcccttatcaGGGTAAAAGTGAAGTACAGctaaagccttttgcagctggagaatgtt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2514652..2514670 /Source="Nicolas_upshift_promotors" /id="U2002" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=171 /SigmaFactorBS="ctgttttcggtccgtaaactccatctatgccatTGTTTTTgg ctcccttatcaGGGTAAAAGTGAAGTACAGctaaagccttttgcagctggagaatgtt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2514659 /Source="Nicolas_upshifts" /id="U2002" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=171 /SigmaFactorBS="ctgttttcggtccgtaaactccatctatgccatTGTTTTTgg ctcccttatcaGGGTAAAAGTGAAGTACAGctaaagccttttgcagctggagaatgtt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 complement(2515263..2515282) /Source="Nicolas_upshift_promotors" /id="U2003" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp="0.898101898101898" /psig="0.898101898101898" /xcortree=1426 /SigmaFactorBS="caggttaagaacacaattcttttttacctcataaaaaaGGCT GTCCAtctctctgttttcTGCATTCTTATTAATAGGGAgggatagaaatggtaaccat a" /listShort="cwlH" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2515282) /Source="Nicolas_upshifts" /id="U2003" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp="0.898101898101898" /psig="0.898101898101898" /xcortree=1426 /SigmaFactorBS="caggttaagaacacaattcttttttacctcataaaaaaGGCT GTCCAtctctctgttttcTGCATTCTTATTAATAGGGAgggatagaaatggtaaccat a" /listShort="cwlH" /GFF_Attribute="listLong" promotor_-35 complement(2515296..2515304) /Source="Nicolas_upshift_promotors" /id="U2003" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp="0.898101898101898" /psig="0.898101898101898" /xcortree=1426 /SigmaFactorBS="caggttaagaacacaattcttttttacctcataaaaaaGGCT GTCCAtctctctgttttcTGCATTCTTATTAATAGGGAgggatagaaatggtaaccat a" /listShort="cwlH" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 2515348..2515355 /Source="Nicolas_upshift_promotors" /id="U2004" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.694305694305694" /psig=1 /xcortree=1830 /SigmaFactorBS="aggtaaaaaagaattgtgttcttaacctggttttCAGTTGAA cagctgaaatggcaCCAGTTATACTAATTTAGATgacggaggttttgactcctgacat c" /listShort="S971, yqeD" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2515370..2515389 /Source="Nicolas_upshift_promotors" /id="U2004" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.694305694305694" /psig=1 /xcortree=1830 /SigmaFactorBS="aggtaaaaaagaattgtgttcttaacctggttttCAGTTGAA cagctgaaatggcaCCAGTTATACTAATTTAGATgacggaggttttgactcctgacat c" /listShort="S971, yqeD" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 2515374..2515439 /Source="Nicolas_S_feature" /locus_tag="new_2649776_2649841" /HighExp="dia15, H2O2, C30, G180, Heat, S8, Paraq, Oxctl, LBGexp, Etha" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S971" upshifts 2515374 /Source="Nicolas_upshifts" /id="U2004" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.694305694305694" /psig=1 /xcortree=1830 /SigmaFactorBS="aggtaaaaaagaattgtgttcttaacctggttttCAGTTGAA cagctgaaatggcaCCAGTTATACTAATTTAGATgacggaggttttgactcctgacat c" /listShort="S971, yqeD" /GFF_Attribute="listLong" CDS 2515440..2516066 /gene="yqeD" /locus_tag="BSU_25720" /old_locus_tag="BSU25720" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 15849754, 15855514, 16850406" /codon_start=1 /transl_table=11 /product="conserved membrane protein of unknown function" /protein_id="NP_390449.1" /db_xref="EnsemblGenomes-Gn:BSU25720" /db_xref="EnsemblGenomes-Tr:CAB14513" /db_xref="GOA:P54449" /db_xref="InterPro:IPR015414" /db_xref="InterPro:IPR032816" /db_xref="SubtiList:BG11632" /db_xref="UniProtKB/Swiss-Prot:P54449" /translation="MLKKVIGILVIIAIISVGFFQKEAWLDAIKAGGMFSVLFSMLLI AADVFFPIVPFALIAALNGAVFGTANGIWITLTGSMLGTILLFFLARYSFRDWARKKV QAYPAIQSYEASFNKNAFTAVLLGRLIPVIPSLVMNVICGLSQVRWHVFFFASLIGKI PNIVVVTIAGANFTSNKLLSISIYGTYILIIMLVIYKKFPHLLKVPKK*" gene 2515440..2516066 /gene="yqeD" /locus_tag="BSU_25720" /old_locus_tag="BSU25720" downshifts 2516034 /Source="Nicolas_upshifts" /id="D1332" /incds=0 /nref=2 /ntot=63 /MaxReadThrough="2.9326" /MaxDrop="2.91074" /score="15.7108141" /energy="-10.3" /TU="U2004" /idTUdmin="U2004" /TUdmin="-22" /isTUend="TRUE" CDS complement(2516085..2516978) /gene="yqeC" /locus_tag="BSU_25730" /old_locus_tag="BSU25730" /EC_number="1.1.1.-" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 10658669, 15231785; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative catabolic 6-phospho-gluconate dehydrogenase (NAD[+]-dependent)" /protein_id="NP_390450.1" /db_xref="EnsemblGenomes-Gn:BSU25730" /db_xref="EnsemblGenomes-Tr:CAB14514" /db_xref="GOA:P54448" /db_xref="InterPro:IPR004849" /db_xref="InterPro:IPR006114" /db_xref="InterPro:IPR006115" /db_xref="InterPro:IPR006183" /db_xref="InterPro:IPR006184" /db_xref="InterPro:IPR008927" /db_xref="InterPro:IPR013328" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG11631" /db_xref="UniProtKB/Swiss-Prot:P54448" /translation="MKIGLIGLGKMGINIGKQFIDRNHQVVGYDVNQAAVDELKAYGA EGTTNLKEFISLLHPPRILWVMVPHGIVDAVLRDVSPLLSKGDMIIEAGNSHYKESIR RYNQMKEAGIHYLDAGTSGGMEGARHGACFMVGGDHEAWEIVEPLFRDTAVENGYLYA GEAGSGHFLKMIHNGIEYGMMAAIGEGFEVLENSQFDFDYEKVARVWNHGSVIRSWLM GLTERAFAKDAKLDQIKGIMHSSGEGKWTVETALDLQTATPVIAMSLMMRYRSLTDDT FTGKVVAALRNEFGGHATEKK*" gene complement(2516085..2516978) /gene="yqeC" /locus_tag="BSU_25730" /old_locus_tag="BSU25730" downshifts complement(2516110) /Source="Nicolas_upshifts" /id="D1333" /incds=0 /nref=4 /ntot=12 /MaxReadThrough="1.46947" /MaxDrop="3.03963" /score="0.698755756" /energy="-8.4" /TU="NA" /idTUdmin="U2003" /TUdmin="-1606" /isTUend="FALSE" promotor_-35 2517161..2517167 /Source="Nicolas_upshift_promotors" /id="U2005" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.874125874125874" /psig="0.998001998001998" /xcortree=3104 /SigmaFactorBS="tctattactgaatctctttatatccataattatcgctttatc CTTGATTtaccatcagttTAAGTTAAAATATGGGAAGGaattcgattttttcagtaaa a" /listShort="yqeB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2517179..2517198 /Source="Nicolas_upshift_promotors" /id="U2005" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.874125874125874" /psig="0.998001998001998" /xcortree=3104 /SigmaFactorBS="tctattactgaatctctttatatccataattatcgctttatc CTTGATTtaccatcagttTAAGTTAAAATATGGGAAGGaattcgattttttcagtaaa a" /listShort="yqeB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2517179 /Source="Nicolas_upshifts" /id="U2005" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.874125874125874" /psig="0.998001998001998" /xcortree=3104 /SigmaFactorBS="tctattactgaatctctttatatccataattatcgctttatc CTTGATTtaccatcagttTAAGTTAAAATATGGGAAGGaattcgattttttcagtaaa a" /listShort="yqeB" /GFF_Attribute="listLong" CDS 2517230..2517952 /gene="yqeB" /locus_tag="BSU_25740" /old_locus_tag="BSU25740" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_390451.2" /db_xref="EnsemblGenomes-Gn:BSU25740" /db_xref="EnsemblGenomes-Tr:CAB14515" /db_xref="GOA:P54447" /db_xref="SubtiList:BG11630" /db_xref="UniProtKB/Swiss-Prot:P54447" /translation="MLQNQSHTLIGVTKTAVFFLYAALAIIGFAIGYFIPQIAKWALS LPWIPLEGPLRLITSFQGSTASFITALLGMCAGIWFAHSVIAMLLSVKITDHTVEFIK GKKVQTIHSDDIALVFMDHKRLVLLGTAGYELVREEIDEKPVNVEKAFRQHHYEWATD GDPFKDQFRRWIPDAPDLSQGAHALLKARHKALQDEEKDDIEEFRLELAQLGIVVRDE GTRQYWRKAETYPPKIQLGEGL*" gene 2517230..2517952 /gene="yqeB" /locus_tag="BSU_25740" /old_locus_tag="BSU25740" CDS complement(2517985..2518395) /gene="nucB" /locus_tag="BSU_25750" /old_locus_tag="BSU25750" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:7746143, 17209033, 21179489" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7746143, 17209033, 21179489; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="sporulation-specific matrix degrading exported DNase" /protein_id="NP_390452.1" /db_xref="EnsemblGenomes-Gn:BSU25750" /db_xref="EnsemblGenomes-Tr:CAB14516" /db_xref="GOA:P42983" /db_xref="InterPro:IPR029476" /db_xref="SubtiList:BG11237" /db_xref="UniProtKB/Swiss-Prot:P42983" /translation="MKKWMAGLFLAAAVLLCLMVPQQIQGASSYDKVLYFPLSRYPET GSHIRDAIAEGHPDICTIDRDGADKRREESLKGIPTKPGYDRDEWPMAVCEEGGAGAD VRYVTPSDNRGAGSWVGNQMSSYPDGTRVLFIVQ*" gene complement(2517985..2518395) /gene="nucB" /locus_tag="BSU_25750" /old_locus_tag="BSU25750" downshifts complement(2518010) /Source="Nicolas_upshifts" /id="D1334" /incds=0 /nref=2 /ntot=20 /MaxReadThrough="0.80212" /MaxDrop="3.40706" /score="-0.144589925" /energy="-9.3" /TU="NA" /idTUdmin="U2006" /TUdmin="-11" /isTUend="TRUE" promotor_-10 complement(2518415..2518433) /Source="Nicolas_upshift_promotors" /id="U2006" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp="0.996003996003996" /psig="0.996003996003996" /xcortree=1115 /SigmaFactorBS="cagcatactaacttcaaatgttaAAAATAttcttcatcaagc gcCCATACATTGAAATGAACAaaggtatggggggatggggatgaaaaaatggatggca g" /listShort="nucB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2518417) /Source="Nicolas_upshifts" /id="U2006" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp="0.996003996003996" /psig="0.996003996003996" /xcortree=1115 /SigmaFactorBS="cagcatactaacttcaaatgttaAAAATAttcttcatcaagc gcCCATACATTGAAATGAACAaaggtatggggggatggggatgaaaaaatggatggca g" /listShort="nucB" /GFF_Attribute="listLong" promotor_-35 complement(2518449..2518454) /Source="Nicolas_upshift_promotors" /id="U2006" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp="0.996003996003996" /psig="0.996003996003996" /xcortree=1115 /SigmaFactorBS="cagcatactaacttcaaatgttaAAAATAttcttcatcaagc gcCCATACATTGAAATGAACAaaggtatggggggatggggatgaaaaaatggatggca g" /listShort="nucB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 2518518..2518526 /Source="Nicolas_upshift_promotors" /id="U2007" /multdbtbs="SigE,SigK" /comp="M5" /sig="SigK" /pcomp="0.595404595404595" /psig="0.595404595404595" /xcortree=1062 /SigmaFactorBS="ttaccaaagccggactcccccgcgagaaatttcccggtaCAG ACACAGacagcctcccggtCACATACATTTACATATAGGcttttgcctacatactttt g" /listShort="spoIVCB" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 2518539 /Source="Nicolas_upshifts" /id="U2007" /multdbtbs="SigE,SigK" /comp="M5" /sig="SigK" /pcomp="0.595404595404595" /psig="0.595404595404595" /xcortree=1062 /SigmaFactorBS="ttaccaaagccggactcccccgcgagaaatttcccggtaCAG ACACAGacagcctcccggtCACATACATTTACATATAGGcttttgcctacatactttt g" /listShort="spoIVCB" /GFF_Attribute="listLong" promotor_-10 2518540..2518559 /Source="Nicolas_upshift_promotors" /id="U2007" /multdbtbs="SigE,SigK" /comp="M5" /sig="SigK" /pcomp="0.595404595404595" /psig="0.595404595404595" /xcortree=1062 /SigmaFactorBS="ttaccaaagccggactcccccgcgagaaatttcccggtaCAG ACACAGacagcctcccggtCACATACATTTACATATAGGcttttgcctacatactttt g" /listShort="spoIVCB" /GFF_Attribute="listLong" /label="promotor_-10" CDS 2518591..2519061 /gene="sigKn" /locus_tag="BSU_25760" /old_locus_tag="BSU25760" /function="16.5: Explore" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:8464402, 7704261, 2536191, 2163341, 10974124, 15187183, 20889742" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8464402, 7704261, 2536191, 2163341, 10974124, 15187183, 20889742; Product type r: regulator" /pseudo /codon_start=1 /transl_table=11 /product="RNA polymerase sporulation-specific sigma-K factor precursor (Sigma-27) (N-terminal half)" /db_xref="GOA:P12254" /db_xref="InterPro:IPR000943" /db_xref="InterPro:IPR007627" /db_xref="InterPro:IPR007630" /db_xref="InterPro:IPR013324" /db_xref="InterPro:IPR013325" /db_xref="InterPro:IPR014284" /db_xref="PSEUDO:CAB14517.2" /db_xref="SubtiList:BG10459" /db_xref="UniProtKB/Swiss-Prot:P12254" /translation="MVTGVFAALGFVVKELVFLVSYVKNNAFPQPLSSSEEKKYLELM AKGDEHARNMLIEHNLRLVAHIVKKFENTGEDAEDLISIGTIGLIKGIESYSAGKGTK LATYAARCIENEIVITKGGCIHPSLIRFNIYGVRIHNGNFFHDKVNNCFFIFKS*" gene 2518591..2519061 /gene="sigKn" /locus_tag="BSU_25760" /old_locus_tag="BSU25760" /pseudo downshifts 2518781 /Source="Nicolas_upshifts" /id="D1335" /incds=1 /nref=2 /ntot=5 /MaxReadThrough="7.53734" /MaxDrop="3.01863" /score="-7.46047649" /energy="-12.1" /TU="U2007" /idTUdmin="U2007" /TUdmin="-132" /isTUend="FALSE" downshifts 2518913 /Source="Nicolas_upshifts" /id="D1336" /incds=1 /nref=44 /ntot=61 /MaxReadThrough="0.8049" /MaxDrop="7.21386" /score="-7.46047649" /energy="-12.1" /TU="NA" /idTUdmin="U2007" /TUdmin=0 /isTUend="TRUE" CDS complement(2518969..2520471) /gene="spoIVCA" /locus_tag="BSU_25770" /old_locus_tag="BSU25770" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:1631085, 2163341, 7704261, 8300549, 8969508, 8655528, 18673456" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1631085, 2163341, 7704261, 8300549, 8969508, 8655528, 18673456; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="site-specific DNA recombinase; skin element" /protein_id="NP_390454.2" /db_xref="EnsemblGenomes-Gn:BSU25770" /db_xref="EnsemblGenomes-Tr:CAB14518" /db_xref="GOA:P17867" /db_xref="InterPro:IPR006118" /db_xref="InterPro:IPR006119" /db_xref="InterPro:IPR011109" /db_xref="InterPro:IPR025827" /db_xref="InterPro:IPR036162" /db_xref="SubtiList:BG10458" /db_xref="UniProtKB/Swiss-Prot:P17867" /translation="MIAIYVRVSTEEQAIKGSSIDSQIEACIKKAGTKDVLKYADEGF SGELLERPALNRLREDASKGLISQVICYDPDRLSRKLMNQLIIDDELRKRNIPLIFVN GEYANSPEGQLFFAMRGAISEFEKAKIKERTSSGRLQKMKKGMIIKDSKLYGYKFVKE KRTLEILEEEAKIIRMIFNYFTDHKSPFFGRVNGIALHLTQMGVKTKKGAKVWHRQVV RQILMNSSYKGEHRQYKYDTEGSYVSKQAGNKSIIKIRPEEEQITVTIPAIVPAEQWD YAQELLGQSKRKHLSISPHNYLLSGLVRCGKCGNTMTGKKRKSHGKDYYVYTCRKNYS GAKDRGCGKEMSENKLNRHVWGEIFKFITNPQKYVSFKEAEQSNHLSDELELIEKEIE KTKKGRKRLLTLISLSDDDDLDIDEIKAQIIELQKKQNQLTEKCNEIQSKMKVLDDTS SSENALKRAIDYFQSIGADNLTLEDKKTIVNFIVKEVTIVDSDTIYIETY*" gene complement(2518969..2520471) /gene="spoIVCA" /locus_tag="BSU_25770" /old_locus_tag="BSU25770" downshifts complement(2518985) /Source="Nicolas_upshifts" /id="D1337" /incds=1 /nref=21 /ntot=131 /MaxReadThrough="2.50085" /MaxDrop="6.35891" /score="-0.144589925" /energy="-9.3" /TU="NA" /idTUdmin="U2008" /TUdmin=4 /isTUend="TRUE" promotor_-10 complement(2520578..2520596) /Source="Nicolas_upshift_promotors" /id="U2008" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp="0.993006993006993" /psig="0.993006993006993" /xcortree=1098 /SigmaFactorBS="gaaacgtttaataacactatagtttaatttaaaatctcCTCA TTtggacaaacagctgttACATAGCATTACCCAAGGGgtgatgcattttatgaaagtg a" /listShort="spoIVCA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2520596) /Source="Nicolas_upshifts" /id="U2008" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp="0.993006993006993" /psig="0.993006993006993" /xcortree=1098 /SigmaFactorBS="gaaacgtttaataacactatagtttaatttaaaatctcCTCA TTtggacaaacagctgttACATAGCATTACCCAAGGGgtgatgcattttatgaaagtg a" /listShort="spoIVCA" /GFF_Attribute="listLong" S_feature complement(2520598..2520899) /Source="Nicolas_S_feature" /locus_tag="new_2655000_2655301_c" /HighExp="dia5, Diami, S8, S7, dia15, C30, G135, S6, G180, LBGtran" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.974" /TUlongSig="NA" /TUlongPSig="NA" /label="S972" promotor_-35 complement(2520613..2520618) /Source="Nicolas_upshift_promotors" /id="U2008" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp="0.993006993006993" /psig="0.993006993006993" /xcortree=1098 /SigmaFactorBS="gaaacgtttaataacactatagtttaatttaaaatctcCTCA TTtggacaaacagctgttACATAGCATTACCCAAGGGgtgatgcattttatgaaagtg a" /listShort="spoIVCA" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2520920..2521339) /gene="arsC" /locus_tag="BSU_25780" /old_locus_tag="BSU25780" /EC_number="1.20.4.4" /function="16.8: Protect" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:11698660, 16192272, 16905151, 8760915, 8969508, 9537360, 17303556, 21258851, 21904062, 23813734" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11698660, 16192272, 16905151, 8760915, 8969508, 9537360, 17303556, 21258851, 21904062, 23813734; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="thioredoxin-coupled arsenate reductase; skin element" /protein_id="NP_390455.1" /db_xref="EnsemblGenomes-Gn:BSU25780" /db_xref="EnsemblGenomes-Tr:CAB14519" /db_xref="GOA:P45947" /db_xref="InterPro:IPR014064" /db_xref="InterPro:IPR023485" /db_xref="InterPro:IPR036196" /db_xref="PDB:1JL3" /db_xref="PDB:1Z2D" /db_xref="PDB:1Z2E" /db_xref="PDB:2IPA" /db_xref="SubtiList:BG11304" /db_xref="UniProtKB/Swiss-Prot:P45947" /translation="MENKIIYFLCTGNSCRSQMAEGWAKQYLGDEWKVYSAGIEAHGL NPNAVKAMKEVGIDISNQTSDIIDSDILNNADLVVTLCGDAADKCPMTPPHVKREHWG FDDPARAQGTEEEKWAFFQRVRDEIGNRLKEFAETGK*" gene complement(2520920..2521339) /gene="arsC" /locus_tag="BSU_25780" /old_locus_tag="BSU25780" downshifts complement(2520944) /Source="Nicolas_upshifts" /id="D1338" /incds=0 /nref=106 /ntot=239 /MaxReadThrough="3.85143" /MaxDrop="6.98965" /score="17.1730317" /energy="-8.6" /TU="U2009" /idTUdmin="U2009" /TUdmin="-1823" /isTUend="FALSE" CDS complement(2521351..2522391) /gene="arsB" /locus_tag="BSU_25790" /old_locus_tag="BSU25790" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 9537360, 15849754, 16850406, 16905151; Product type t: transporter" /codon_start=1 /transl_table=11 /product="arsenite efflux transporter; skin element" /protein_id="NP_390456.2" /db_xref="EnsemblGenomes-Gn:BSU25790" /db_xref="EnsemblGenomes-Tr:CAB14520" /db_xref="GOA:P45946" /db_xref="InterPro:IPR002657" /db_xref="InterPro:IPR004706" /db_xref="SubtiList:BG11303" /db_xref="UniProtKB/Swiss-Prot:P45946" /translation="MKRLSFLDRYLTIWIFLAMALGIGLGFIFPSFVGGLNKLQVGTT SIPLAIGLVLMMYPPLAKVRYEEIGRVFKDIKVLILSLVQNWIIGPTLMFILAIIFLP DKPEYMIGLIMIGLARCIAMVIVWNDLSKGDTEYAAGLVAFNSIFQMLFFSVYAYIFV TVIPQWLGMEGAVVNITMAEVAKSVFIYLGVPFIAGMVTRYIFVKVKGKEWYEKVFIP KISPITLIALLFTIIVMFSLKGDVIVSLPLDVVRVAIPLLIYFVLMFFVSFFLGKKIG ANYAVTTTLAFTAGSNNFELAIAVAVGVFGIHSGAAFAAVIGPLVEVPVMIALVKVAL WFQRKYFGSHSM*" gene complement(2521351..2522391) /gene="arsB" /locus_tag="BSU_25790" /old_locus_tag="BSU25790" CDS complement(2522414..2522854) /gene="yqcK" /locus_tag="BSU_25800" /old_locus_tag="BSU25800" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 8760915, 8969508, 9537360, 16905151, 21749987; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative thiol lyase" /protein_id="NP_390457.2" /db_xref="EnsemblGenomes-Gn:BSU25800" /db_xref="EnsemblGenomes-Tr:CAB14521" /db_xref="GOA:P45945" /db_xref="InterPro:IPR004360" /db_xref="InterPro:IPR029068" /db_xref="SubtiList:BG11302" /db_xref="UniProtKB/Swiss-Prot:P45945" /translation="MKYVHVGVNVVSLEKSINFYEKVFGVKAVKVKTDYAKFLLETPG LNFTLNVADEVKGNQVNHFGFQVDSLEEVLKHKKRLEKEGFFAREEMDTTCCYAVQDK FWITDPDGNEWEFFYTKSNSEVQKQDSSSCCVTPPSDITTNSCC*" gene complement(2522414..2522854) /gene="yqcK" /locus_tag="BSU_25800" /old_locus_tag="BSU25800" CDS complement(2522915..2523232) /gene="arsR" /locus_tag="BSU_25810" /old_locus_tag="BSU25810" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:9537360, 16430705, 19632156" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9537360, 16430705, 19632156; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator (ArsR-arsenate); skin element" /protein_id="NP_390458.1" /db_xref="EnsemblGenomes-Gn:BSU25810" /db_xref="EnsemblGenomes-Tr:CAB14522" /db_xref="GOA:P45949" /db_xref="InterPro:IPR001845" /db_xref="InterPro:IPR011991" /db_xref="InterPro:IPR018334" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG11301" /db_xref="UniProtKB/Swiss-Prot:P45949" /translation="MDETKSELLRKYEQKFKALADQKRLEIMYELCQRGKTCVCDLTE IFEVTQSKLSYHLKILLDANLITKETKGTWSYYDLNDEEVNGLLSEELCCIFRKKGEG DCC*" gene complement(2522915..2523232) /gene="arsR" /locus_tag="BSU_25810" /old_locus_tag="BSU25810" promotor_-10 complement(2523263..2523282) /Source="Nicolas_upshift_promotors" /id="U2009" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.645354645354645" /psig="0.974025974025974" /xcortree=1792 /SigmaFactorBS="tttagcgggttttacaattaatcaaaataaattgatttattT GCTTGCAttaatttaaaaatcATGAGTATAATAAATACATCaaaaaaaattgattaaa g" /listShort="arsR, yqcK, arsB, arsC, S972, spoIVCA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2523285) /Source="Nicolas_upshifts" /id="U2009" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.645354645354645" /psig="0.974025974025974" /xcortree=1792 /SigmaFactorBS="tttagcgggttttacaattaatcaaaataaattgatttattT GCTTGCAttaatttaaaaatcATGAGTATAATAAATACATCaaaaaaaattgattaaa g" /listShort="arsR, yqcK, arsB, arsC, S972, spoIVCA" /GFF_Attribute="listLong" promotor_-35 complement(2523297..2523304) /Source="Nicolas_upshift_promotors" /id="U2009" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.645354645354645" /psig="0.974025974025974" /xcortree=1792 /SigmaFactorBS="tttagcgggttttacaattaatcaaaataaattgatttattT GCTTGCAttaatttaaaaatcATGAGTATAATAAATACATCaaaaaaaattgattaaa g" /listShort="arsR, yqcK, arsB, arsC, S972, spoIVCA" /GFF_Attribute="listLong" /label="promotor_-35" downshifts complement(2523587) /Source="Nicolas_upshifts" /id="D1339" /incds=0 /nref=6 /ntot=37 /MaxReadThrough="1.61397" /MaxDrop="5.36072" /score="17.1730317" /energy="-8.6" /TU="NA" /idTUdmin="U2010" /TUdmin=0 /isTUend="TRUE" CDS complement(2523604..2524368) /gene="yqcI" /locus_tag="BSU_25820" /old_locus_tag="BSU25820" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 8760915, 8969508; Product type h:extrachromosomal origin" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function; skin element" /protein_id="NP_390459.2" /db_xref="EnsemblGenomes-Gn:BSU25820" /db_xref="EnsemblGenomes-Tr:CAB14523" /db_xref="InterPro:IPR014988" /db_xref="SubtiList:BG11300" /db_xref="UniProtKB/Swiss-Prot:P45944" /translation="MTELYAKSDLEKIKETLPGWQLDSFNYLNEKIGDKENKFPCIPG RQAFLSDQLRIAFVGDPRNPETAKELAPLLTRYGTISRETGKYASLTVIFHTPEELLT DYKIEDYESLFWQLLNSLSMEDPADWPDDIPENPDNFQWEYCFNGEPYFVLCATPAHS KRKSRSFPYFMLTFQPRWVFEDLNDTTAFGRNMSKQIRKRLEAYDEVPIHPHLGWYGK KDNLEWKQYFLRDDENQVSQCPFMKMKNLFKKKRSD*" gene complement(2523604..2524368) /gene="yqcI" /locus_tag="BSU_25820" /old_locus_tag="BSU25820" promotor_-10 complement(2524387..2524406) /Source="Nicolas_upshift_promotors" /id="U2010" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.986013986013986" /psig="0.986013986013986" /xcortree=1287 /SigmaFactorBS="atattcatttggatatatgaaaaagtaattagACATTCACCT ccttcgtgctcccGCAATACATTATGATAAATGccttcggaggtggatttattgactg a" /listShort="yqcI" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2524401) /Source="Nicolas_upshifts" /id="U2010" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.986013986013986" /psig="0.986013986013986" /xcortree=1287 /SigmaFactorBS="atattcatttggatatatgaaaaagtaattagACATTCACCT ccttcgtgctcccGCAATACATTATGATAAATGccttcggaggtggatttattgactg a" /listShort="yqcI" /GFF_Attribute="listLong" promotor_-35 complement(2524420..2524429) /Source="Nicolas_upshift_promotors" /id="U2010" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.986013986013986" /psig="0.986013986013986" /xcortree=1287 /SigmaFactorBS="atattcatttggatatatgaaaaagtaattagACATTCACCT ccttcgtgctcccGCAATACATTATGATAAATGccttcggaggtggatttattgactg a" /listShort="yqcI" /GFF_Attribute="listLong" /label="promotor_-35" misc_feature 2524763..2524782 /Source="Nicolas_upshift_promotors" /id="U2011" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.441558441558442" /psig="0.995004995004995" /xcortree=2867 /SigmaFactorBS="tgcggtctcaccgaaaatttaaattgcggtgccctatttcct ttttctgcgaacgaaaaCTTGTTAATATTTACAGTACtagtagagttaagggaagggt g" /listShort="rapE" /listLong="phrE, yqzI, yqcG, yqcF" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 2524764 /Source="Nicolas_upshifts" /id="U2011" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.441558441558442" /psig="0.995004995004995" /xcortree=2867 /SigmaFactorBS="tgcggtctcaccgaaaatttaaattgcggtgccctatttcct ttttctgcgaacgaaaaCTTGTTAATATTTACAGTACtagtagagttaagggaagggt g" /listShort="rapE" /listLong="phrE, yqzI, yqcG, yqcF" CDS 2524811..2525938 /gene="rapE" /locus_tag="BSU_25830" /old_locus_tag="BSU25830" /EC_number="3.1.-.-" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:8760915, 8969508, 10629174, 11679073, 12897006" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8760915, 8969508, 10629174, 11679073, 12897006; Product type r: regulator" /codon_start=1 /transl_table=11 /product="response regulator aspartate phosphatase; skin element" /protein_id="NP_390460.2" /db_xref="EnsemblGenomes-Gn:BSU25830" /db_xref="EnsemblGenomes-Tr:CAB14524" /db_xref="GOA:P45943" /db_xref="InterPro:IPR011990" /db_xref="InterPro:IPR013026" /db_xref="InterPro:IPR019734" /db_xref="SubtiList:BG11299" /db_xref="UniProtKB/Swiss-Prot:P45943" /translation="MISITSAEVGMKINEWHRHIQKFNVTDAEMLKAEIERDIEVMEE DQDLLIYYQLMAFRHKIMLEYTLPSDENRMELSEYLNKIEGHKKKLDNMRAYYYNFFR GMYEFRNGEYTRAITYYKKAERKIPTISDKIEKAEFYFKLSEVYYHMKMTHISMHYAE LSYNIYKKHELYSVRRIQCHFVIAGNYDDLENHEKALPHLQEALKGAELLKSKNTHIY ATAFFNLGNCYHKMDNLNKAARYIEQALVQYRKINSDVLPQAYHDLALIYFKQGKKEQ AMDCFRKGIRSAVDFKDELFMNLFEALDVLYIRNGDTPKLLNIFSRLENGKGYPYLEE LALLGGNLFDYNGKIEDSIICFKKMVYAQKQISKGECMYEI*" gene 2524811..2525938 /gene="rapE" /locus_tag="BSU_25830" /old_locus_tag="BSU25830" promotor_-35 2525818..2525821 /Source="Nicolas_upshift_promotors" /id="U2012" /multdbtbs="SigA,SigH" /comp="M7" /sig="SigA" /pcomp="0.748251748251748" /psig=1 /xcortree=473 /SigmaFactorBS="gaacggcaaaggatacccttatctggaagagctggcATTGtt aggaggcaaccttTTCGATTATAATGGAAAAATagaggatagtatcatctgtttcaag a" /listShort="phrE, yqzI" /listLong="yqcG, yqcF" /label="promotor_-35" promotor_-10 2525837..2525856 /Source="Nicolas_upshift_promotors" /id="U2012" /multdbtbs="SigA,SigH" /comp="M7" /sig="SigA" /pcomp="0.748251748251748" /psig=1 /xcortree=473 /SigmaFactorBS="gaacggcaaaggatacccttatctggaagagctggcATTGtt aggaggcaaccttTTCGATTATAATGGAAAAATagaggatagtatcatctgtttcaag a" /listShort="phrE, yqzI" /listLong="yqcG, yqcF" /label="promotor_-10" upshifts 2525842 /Source="Nicolas_upshifts" /id="U2012" /multdbtbs="SigA,SigH" /comp="M7" /sig="SigA" /pcomp="0.748251748251748" /psig=1 /xcortree=473 /SigmaFactorBS="gaacggcaaaggatacccttatctggaagagctggcATTGtt aggaggcaaccttTTCGATTATAATGGAAAAATagaggatagtatcatctgtttcaag a" /listShort="phrE, yqzI" /listLong="yqcG, yqcF" CDS 2525928..2526062 /gene="phrE" /locus_tag="BSU_25840" /old_locus_tag="BSU25840" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:10629174" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10629174; Product type r: regulator" /codon_start=1 /transl_table=11 /product="regulator peptide of the activity of phosphataseRapE; skin element" /protein_id="NP_390461.1" /db_xref="EnsemblGenomes-Gn:BSU25840" /db_xref="EnsemblGenomes-Tr:CAB14525" /db_xref="SubtiList:BG11521" /db_xref="UniProtKB/Swiss-Prot:O32025" /translation="MKSKLFISLSAVLIGLAFFGSMYNGEMKEASRNVTLAPTHEFLV *" gene 2525928..2526062 /gene="phrE" /locus_tag="BSU_25840" /old_locus_tag="BSU25840" downshifts 2526077 /Source="Nicolas_upshifts" /id="D1340" /incds=0 /nref=48 /ntot=239 /MaxReadThrough="3.50767" /MaxDrop="5.81353" /score="18.2148871" /energy="-8" /TU="U2012" /idTUdmin="U2011" /TUdmin=257 /isTUend="FALSE" CDS 2526172..2526330 /gene="yqzI" /locus_tag="BSU_25850" /old_locus_tag="BSU25850" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein; skin element" /protein_id="NP_390462.1" /db_xref="EnsemblGenomes-Gn:BSU25850" /db_xref="EnsemblGenomes-Tr:CAB14526" /db_xref="SubtiList:BG13775" /db_xref="UniProtKB/Swiss-Prot:O32026" /translation="MDLFDECLEALGKNKEILSEELTAKYYELLSNSFPLHLGDESSG KKFVVINL*" gene 2526172..2526330 /gene="yqzI" /locus_tag="BSU_25850" /old_locus_tag="BSU25850" promotor_-35 2526638..2526644 /Source="Nicolas_upshift_promotors" /id="U2013" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.949050949050949" /psig="0.995004995004995" /xcortree=2986 /SigmaFactorBS="tcgaatgattcatttccaccatttgatccacataacagTTAG TTTcatcattcttcCATGGTAATATTTTGTTATGacgattaaatgaaaggatatgatc a" /listShort="yqcG, yqcF" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2526656..2526675 /Source="Nicolas_upshift_promotors" /id="U2013" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.949050949050949" /psig="0.995004995004995" /xcortree=2986 /SigmaFactorBS="tcgaatgattcatttccaccatttgatccacataacagTTAG TTTcatcattcttcCATGGTAATATTTTGTTATGacgattaaatgaaaggatatgatc a" /listShort="yqcG, yqcF" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2526660 /Source="Nicolas_upshifts" /id="U2013" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.949050949050949" /psig="0.995004995004995" /xcortree=2986 /SigmaFactorBS="tcgaatgattcatttccaccatttgatccacataacagTTAG TTTcatcattcttcCATGGTAATATTTTGTTATGacgattaaatgaaaggatatgatc a" /listShort="yqcG, yqcF" /GFF_Attribute="listLong" CDS 2526700..2528295 /gene="rttG" /locus_tag="BSU_25860" /old_locus_tag="BSU25860" /function="16.13: Shape" /function="16.6: Maintain" /function="17.2: Prophage functions" /experiment="publication(s) with functional evidences, PMID:22200572, 27450630" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 22200572, 27450630; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="phage ribonuclease toxin; skin element" /protein_id="NP_390463.1" /db_xref="EnsemblGenomes-Gn:BSU25860" /db_xref="EnsemblGenomes-Tr:CAB14527" /db_xref="GOA:P45942" /db_xref="InterPro:IPR006829" /db_xref="InterPro:IPR026835" /db_xref="InterPro:IPR027797" /db_xref="SubtiList:BG11298" /db_xref="UniProtKB/Swiss-Prot:P45942" /translation="MKVFEAKTLLTEAEKRAQEYKDLKSKMVKLKKAFKAVADLDDSE FSGKGANNIKSFYEDQAGIADQWIDLIEMKISFLTSIPGFLEDANLSDAYIEETFLAH ELANAYTKSKSIMSEQKKAMKDILNDINDILPLDLFSTETFKNELSSAEKKRKEAIEK MDEVDQNLTSEYGLSEANEQMIQADYQALMNATAKGKSASPIHYNAKAYRDSEIHKMT EDVKKQSTDYISFKDQQAEQRRIAKEQEELANRPWYEKSWDAVCNFTGEVSGYYDYKR AADGVDPVTGEKLTAGQRVAAGAMAAAGYIPIVGWAGKLAKGGKAVYSTSKALYRADK ALDVYKTPKTFHALQNSSKGLYGLASANGFSEAITGRDMFGNKVSKERQEQSLSGAMA MLVPFGARGINKKLNAKSSSRVSEASTNTSKKPKVPKTYKRPTYFRKGVRDKVWENAK DSTGSVKDPLTKQVMKKDEPWDMGHKPGYEFRKHQQSAMERNISRKQFLDEHNNPDHY QPELPSSNRSHKGEDMTDDYFGD*" gene 2526700..2528295 /gene="rttG" /locus_tag="BSU_25860" /old_locus_tag="BSU25860" CDS 2528310..2528888 /gene="rttF" /locus_tag="BSU_25870" /old_locus_tag="BSU25870" /function="17.2: Prophage functions" /experiment="publication(s) with functional evidences, PMID:22200572" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 22200572; Product type f: factor" /codon_start=1 /transl_table=11 /product="antitoxin factor of ribonuclease toxin RttG; skin element" /protein_id="NP_390464.1" /db_xref="EnsemblGenomes-Gn:BSU25870" /db_xref="EnsemblGenomes-Tr:CAB14528" /db_xref="InterPro:IPR020941" /db_xref="SubtiList:BG11297" /db_xref="UniProtKB/Swiss-Prot:P45941" /translation="MGVTQENKVIARTVLGAFGGKPKVTKYWDDNKNSSIDILSVSDQ PQEGITSYSTLGLSDHSINYEVNGTPLRIEIVAAMESASDIYANVLSTCAFNIINSNF TCAPGVIFKNVISMYDQETDMKHIMFVPPFLWEEDLELLEFSNKNVTWLMALPISEGE LQVAEKHGSDYLQDLLESKQIDIFDIKRESVV*" gene 2528310..2528888 /gene="rttF" /locus_tag="BSU_25870" /old_locus_tag="BSU25870" S_feature complement(2528934..2529129) /Source="Nicolas_S_feature" /locus_tag="new_2663336_2663531_c" /HighExp="BT, S8, C30, HiOs, ferm, nit, S2, S7, BC, Lbstat" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.997" /TUlongSig="NA" /TUlongPSig="NA" /label="S973" CDS 2529006..2529152 /locus_tag="BSU_25875" /old_locus_tag="BSU25875" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_009513979.1" /translation="MINEEKHTNPQANNNIFGRIDTWYSVHRSSNLRENKERPAYYVA GPYL*" gene 2529006..2529152 /locus_tag="BSU_25875" /old_locus_tag="BSU25875" CDS complement(2529149..2529511) /gene="yqxJ" /locus_tag="BSU_25880" /old_locus_tag="BSU25880" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein; skin element" /protein_id="NP_390465.1" /db_xref="EnsemblGenomes-Gn:BSU25880" /db_xref="EnsemblGenomes-Tr:CAB14529" /db_xref="InterPro:IPR035945" /db_xref="SubtiList:BG10507" /db_xref="UniProtKB/Swiss-Prot:P24809" /translation="MVTVEERLDNLEKKVEKQAFQLRLVQQLAADYDRFGLFDQVLAY DLSEKQYQELRELTSQYTDKIKNGEEVSLHNFTEEFKRILKDIEKEVDFEKFISLWLK GPEEGFGFSKALHNHFFN*" gene complement(2529149..2529511) /gene="yqxJ" /locus_tag="BSU_25880" /old_locus_tag="BSU25880" downshifts complement(2529174) /Source="Nicolas_upshifts" /id="D1341" /incds=0 /nref=227 /ntot=262 /MaxReadThrough="4.48269" /MaxDrop="6.26554" /score="-2.16437819" /energy="-9.9" /TU="U2014" /idTUdmin="U2014" /TUdmin="-198" /isTUend="FALSE" CDS complement(2529527..2530006) /gene="yqxI" /locus_tag="BSU_25890" /old_locus_tag="BSU25890" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein; skin element" /protein_id="NP_390466.1" /db_xref="EnsemblGenomes-Gn:BSU25890" /db_xref="EnsemblGenomes-Tr:CAB14530" /db_xref="SubtiList:BG10506" /db_xref="UniProtKB/Swiss-Prot:P24812" /translation="MFKKLLLATSALTFSLSLVLPLDGHAKAQEVTLQAQQEVTYQTP VKLSELPTNTTEQSGEFHTNGIKKWIAKEAMKATASALRHGGRIVGEVVDELGGSAGK TFAKHTDDVADALDELVKRGDVVEDAIIDTVSSYLIDAGVKSSTARTIASVFTFLAF* " gene complement(2529527..2530006) /gene="yqxI" /locus_tag="BSU_25890" /old_locus_tag="BSU25890" downshifts 2530000 /Source="Nicolas_upshifts" /id="D1342" /incds=0 /nref=1 /ntot=12 /MaxReadThrough="1.00897" /MaxDrop="4.14855" /score="2.6302535" /energy="-6.8" /TU="NA" /idTUdmin="U2013" /TUdmin=1100 /isTUend="FALSE" promotor_-10 complement(2530035..2530054) /Source="Nicolas_upshift_promotors" /id="U2014" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.410589410589411" /psig="0.997002997002997" /xcortree=3239 /SigmaFactorBS="atagttcaaaattattctaatatttgagtaaaaagtatTATT TTTCtagtctgaacatAATGTTATCATTTACATGTAaataatttaaaagaaagggatt g" /listShort="yqxI, yqxJ, S973" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2530052) /Source="Nicolas_upshifts" /id="U2014" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.410589410589411" /psig="0.997002997002997" /xcortree=3239 /SigmaFactorBS="atagttcaaaattattctaatatttgagtaaaaagtatTATT TTTCtagtctgaacatAATGTTATCATTTACATGTAaataatttaaaagaaagggatt g" /listShort="yqxI, yqxJ, S973" /GFF_Attribute="listLong" promotor_-35 complement(2530067..2530074) /Source="Nicolas_upshift_promotors" /id="U2014" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.410589410589411" /psig="0.997002997002997" /xcortree=3239 /SigmaFactorBS="atagttcaaaattattctaatatttgagtaaaaagtatTATT TTTCtagtctgaacatAATGTTATCATTTACATGTAaataatttaaaagaaagggatt g" /listShort="yqxI, yqxJ, S973" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 2530095..2530100 /Source="Nicolas_upshift_promotors" /id="U2015" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.907092907092907" /psig="0.907092907092907" /xcortree=960 /SigmaFactorBS="aaaaataatactttttactcaaatattAGAATAattttgaac tatctgTAACAAAATAAACATAAGTatctccttgagaaagatactcaaggagactatt t" /listShort="S974, S975" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2530116..2530134 /Source="Nicolas_upshift_promotors" /id="U2015" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.907092907092907" /psig="0.907092907092907" /xcortree=960 /SigmaFactorBS="aaaaataatactttttactcaaatattAGAATAattttgaac tatctgTAACAAAATAAACATAAGTatctccttgagaaagatactcaaggagactatt t" /listShort="S974, S975" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2530128 /Source="Nicolas_upshifts" /id="U2015" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.907092907092907" /psig="0.907092907092907" /xcortree=960 /SigmaFactorBS="aaaaataatactttttactcaaatattAGAATAattttgaac tatctgTAACAAAATAAACATAAGTatctccttgagaaagatactcaaggagactatt t" /listShort="S974, S975" /GFF_Attribute="listLong" S_feature 2530132..2530328 /Source="Nicolas_S_feature" /locus_tag="new_2664534_2664730" /HighExp="LoTm, S4, S3, S6, S5, B36, S7, B60, S8, BT" /AntisenseName="cwlA" /AntisenseCor="-0.216639314662711" /AntisenseRegPval="-3.5" /CDS_PredictionProba="NA" /TUshortSig="SigEF" /TUshortPSig="0.907" /TUlongSig="NA" /TUlongPSig="NA" /label="S974" CDS complement(2530171..2530989) /gene="cwlA" /locus_tag="BSU_25900" /old_locus_tag="BSU25900" /EC_number="3.5.1.28" /experiment="publication(s) with functional evidences, PMID:1683402, 2127796, 7907356" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1683402, 2127796, 7907356; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="N-acetylmuramoyl-L-alanine amidase; skin element" /protein_id="NP_390467.1" /db_xref="EnsemblGenomes-Gn:BSU25900" /db_xref="EnsemblGenomes-Tr:CAB14531" /db_xref="GOA:P24808" /db_xref="InterPro:IPR002477" /db_xref="InterPro:IPR002502" /db_xref="InterPro:IPR036365" /db_xref="InterPro:IPR036366" /db_xref="InterPro:IPR036505" /db_xref="SubtiList:BG10505" /db_xref="UniProtKB/Swiss-Prot:P24808" /translation="MAIKVVKNLVSKSKYGLKCPNPMKAEYITIHNTANDASAANEIS YMKNNSSSTSFHFAVDDKQVIQGIPTNRNAWHTGDGTNGTGNRKSIGVEICYSKSGGV RYKAAEKLAIKFVAQLLKERGWGIDRVRKHQDWNGKYCPHRILSEGRWIQVKTAIEAE LKKLGGKTNSSKASVAKKKTTNTSSKKTSYALPSGIFKVKSPMMRGEKVTQIQKALAA LYFYPDKGAKNNGIDGVYGPKTADAIRRFQSMYGLTQDGIYGPKTKAKLEALLK*" gene complement(2530171..2530989) /gene="cwlA" /locus_tag="BSU_25900" /old_locus_tag="BSU25900" promotor_-35 2530302..2530308 /Source="Nicolas_upshift_promotors" /id="U2016" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=113 /SigmaFactorBS="tgttttcggaccatacacgccgtcaatgccgtTGTTTTTtgc tcctttatccGGGTAAAAGTATAGTGCAGccagtgctttttgaatttgtgttaccttt t" /listShort="S975" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2530322..2530340 /Source="Nicolas_upshift_promotors" /id="U2016" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=113 /SigmaFactorBS="tgttttcggaccatacacgccgtcaatgccgtTGTTTTTtgc tcctttatccGGGTAAAAGTATAGTGCAGccagtgctttttgaatttgtgttaccttt t" /listShort="S975" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 2530330..2531652 /Source="Nicolas_S_feature" /locus_tag="new_2664732_2666054" /HighExp="M9-stat, LoTm, S4, B60, S3, T1.0H, T0.30H, S5, T1.30H, S6" /AntisenseName="yqxH" /AntisenseCor="0.21547411495493299" /AntisenseRegPval="-3.4" /CDS_PredictionProba="NA" /TUshortSig="SigB, SigEF" /TUshortPSig="0.999, 0.907" /TUlongSig="NA" /TUlongPSig="NA" /label="S975" upshifts 2530330 /Source="Nicolas_upshifts" /id="U2016" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=113 /SigmaFactorBS="tgttttcggaccatacacgccgtcaatgccgtTGTTTTTtgc tcctttatccGGGTAAAAGTATAGTGCAGccagtgctttttgaatttgtgttaccttt t" /listShort="S975" /GFF_Attribute="listLong" CDS complement(2531034..2531456) /gene="yqxH" /locus_tag="BSU_25910" /old_locus_tag="BSU25910" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 25176138; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative holin; skin element" /protein_id="NP_390468.1" /db_xref="EnsemblGenomes-Gn:BSU25910" /db_xref="EnsemblGenomes-Tr:CAB14532" /db_xref="GOA:P24811" /db_xref="InterPro:IPR006480" /db_xref="SubtiList:BG10504" /db_xref="UniProtKB/Swiss-Prot:P24811" /translation="MEETSLFINFETLDLARVYLFGGVKYLDLLLVLSIIDVLTGVIK AWKFKKLRSRSAWFGYVRKLLNFFAVILANVIDTVLNLNGVLTFGTVLFYIANEGLSI TENLAQIGVKIPSSITDRLQTIENEKEQSKNNADKAAG*" gene complement(2531034..2531456) /gene="yqxH" /locus_tag="BSU_25910" /old_locus_tag="BSU25910" CDS complement(2531501..2532394) /gene="yqxG" /locus_tag="BSU_25920" /old_locus_tag="BSU25920" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 25176138; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative phage-related lytic exoenzyme; skin element" /protein_id="NP_390469.1" /db_xref="EnsemblGenomes-Gn:BSU25920" /db_xref="EnsemblGenomes-Tr:CAB14533" /db_xref="SubtiList:BG11069" /db_xref="UniProtKB/Swiss-Prot:P24810" /translation="MASYSFQFSTDATGKPGAAKPYREGNRDFVVPVASISGNSELLT NAVLKATEVYTQYGQDRLGQVLISKVKGHAYSDREGTLFIEESNDMNSWTTISSLVVK ANTLGETEWIHLTKRYFRFRYANGNLQQSEFLLYQSLGAGEEDININHTVPITAVAPF SVQLDKSGLTNDGRLKVQTEGLNLSSLDTQSKTMDIVFHDKTETIGEGNPFTVGSFKT LLIEVYGTAETSELKFWGKSLSGTKRALRGQKVDDGTFATSTKGKSEAWSFSITGFKE IVMELTALTNGNFSVRGTAVS*" gene complement(2531501..2532394) /gene="yqxG" /locus_tag="BSU_25920" /old_locus_tag="BSU25920" CDS complement(2532482..2532646) /gene="yqcE" /locus_tag="BSU_25930" /old_locus_tag="BSU25930" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved phage protein of unknown function; skin element" /protein_id="NP_390470.1" /db_xref="EnsemblGenomes-Gn:BSU25930" /db_xref="EnsemblGenomes-Tr:CAB14534" /db_xref="InterPro:IPR010022" /db_xref="SubtiList:BG11296" /db_xref="UniProtKB/Swiss-Prot:P45940" /translation="MNYWVLALHYNWASSEMVKQAIHLKDCSPEDLQEGIEKKLITAE QYKEITGEAI*" gene complement(2532482..2532646) /gene="yqcE" /locus_tag="BSU_25930" /old_locus_tag="BSU25930" CDS complement(2532643..2532978) /gene="yqcD" /locus_tag="BSU_25940" /old_locus_tag="BSU25940" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved phage protein of unknown function; skin element" /protein_id="NP_390471.1" /db_xref="EnsemblGenomes-Gn:BSU25940" /db_xref="EnsemblGenomes-Tr:CAB14535" /db_xref="InterPro:IPR019094" /db_xref="InterPro:IPR035950" /db_xref="SubtiList:BG11295" /db_xref="UniProtKB/Swiss-Prot:P45939" /translation="MNIGEAILFKYPTADPTKDFIVQNNGDGTPSYIAEWNIRAPIPT EAELKTWWEELQSTSAYEPPVQVDLLARELSQEKLARKQLEELNQTLGSELSKIKLQL LTLQGGQGS*" gene complement(2532643..2532978) /gene="yqcD" /locus_tag="BSU_25940" /old_locus_tag="BSU25940" CDS complement(2532988..2534088) /gene="yqcC" /locus_tag="BSU_25950" /old_locus_tag="BSU25950" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 8760915, 8969508" /codon_start=1 /transl_table=11 /product="conserved phage protein of unknown function; skin element" /protein_id="NP_390472.2" /db_xref="EnsemblGenomes-Gn:BSU25950" /db_xref="EnsemblGenomes-Tr:CAB14536" /db_xref="InterPro:IPR008983" /db_xref="SubtiList:BG11294" /db_xref="UniProtKB/Swiss-Prot:P45938" /translation="MAYDAKTDWLPDDPINEDDVNRWEKGIQDAHKDLAVHKNDMNNP HNTTKAQIGLGNVDNVQQASKKEFEEHRNDLQRHITPVERENWNAKETIVGAQEKADK ALSDAKYYVDTNYKNNNLTLITGDNAIQDARTGGEEYPLGLTLMDIGQGNTTGYPLGY GIVKNEKYNNYRFTQYFYGTGNESGTYYDSTGVWIRHWWSGSGWTPWQKISGFAHANI GTTGVQYLKKIDHTKIAFNRVIKDSHNAFDTKNNRFIAPNDGMYLIGASIYTLNYTSY INFHLKVYLNGKAYKTLHHVRGDFQEKDNGMNLGLNGNATVPMNKGDYVEIWCYCNYG GDETLKRAVDDKNGVFNFFDIQELGGRNYPRF*" gene complement(2532988..2534088) /gene="yqcC" /locus_tag="BSU_25950" /old_locus_tag="BSU25950" CDS complement(2534091..2534363) /gene="yqcB" /locus_tag="BSU_25960" /old_locus_tag="BSU25960" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved phage protein of unknown function; skin element" /protein_id="NP_390473.1" /db_xref="EnsemblGenomes-Gn:BSU25960" /db_xref="EnsemblGenomes-Tr:CAB14537" /db_xref="SubtiList:BG11293" /db_xref="UniProtKB/Swiss-Prot:P45937" /translation="MITQLYRERTAADLKNRISKVLLNGNETEIVELTIQGAVVTVLT QREEDIKHIKSVQILDDQNNVITERTTDLDVSNNRTLDFRITFEVV*" gene complement(2534091..2534363) /gene="yqcB" /locus_tag="BSU_25960" /old_locus_tag="BSU25960" CDS complement(2534360..2534938) /gene="yqcA" /locus_tag="BSU_25970" /old_locus_tag="BSU25970" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 2238468, 8760915, 8969508; Product type s: structure" /codon_start=1 /transl_table=11 /product="putative phage tail baseplate protein; skin element" /protein_id="NP_390474.2" /db_xref="EnsemblGenomes-Gn:BSU25970" /db_xref="EnsemblGenomes-Tr:CAB14538" /db_xref="InterPro:IPR018755" /db_xref="SubtiList:BG11292" /db_xref="UniProtKB/Swiss-Prot:P45936" /translation="MSKLDEMTAYLPPFLTKLKEMAELLKAEAPEFEKQNNSIFDLTD QLFVTTATWGLERWEKILNVPRESGDTDEIRRLRLISKMSNIPPATYRAIEHALNRFL KNPSAQVRLLPGEYRFKVDIDIDDMQHMSELIETLENMKPAHLAYTLRAALNEPLQIK DTVILNNRRYRKASELKVGYSVTLNNNEVVLV*" gene complement(2534360..2534938) /gene="yqcA" /locus_tag="BSU_25970" /old_locus_tag="BSU25970" CDS complement(2534922..2535968) /gene="yqbT" /locus_tag="BSU_25980" /old_locus_tag="BSU25980" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type s: structure" /codon_start=1 /transl_table=11 /product="putative phage baseplate assembly protein; skin element" /protein_id="NP_390475.1" /db_xref="EnsemblGenomes-Gn:BSU25980" /db_xref="EnsemblGenomes-Tr:CAB14539" /db_xref="InterPro:IPR006949" /db_xref="SubtiList:BG11291" /db_xref="UniProtKB/Swiss-Prot:P45935" /translation="MFEDQTYESIMDRMLNSISADIDKREGSVIYNALAPVAAELAKS YIWLDTVLELVFSDTAQGEFLDRRATEAGIERTAATKAVRAGEFTEGVTIPVGSRFYV DNLYFQYTADGTLECETAGEAGNANISGQNLLSLDTIPGLQKAIVKEILIPGREEEDD DSLRARYFTRVRREAVSANKAHYKQWAEEVDGVGKVKVFPLWNGDGTVKIVVTNANLE PASDILISKVKNYIDPEPGQGEGQAPIGAFVTVESAVWKEVEISAEVLPEVNSSIDQV KQEIESGVLNLFKKIAFEDNVIRLSQINNIVYNSPSVSDYADIKINGVAENLVLSAVE IPKLGQVNIIEQTR*" gene complement(2534922..2535968) /gene="yqbT" /locus_tag="BSU_25980" /old_locus_tag="BSU25980" CDS complement(2535961..2536386) /gene="yqbS" /locus_tag="BSU_25990" /old_locus_tag="BSU25990" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved phage protein of unknown function; skin element" /protein_id="NP_390476.1" /db_xref="EnsemblGenomes-Gn:BSU25990" /db_xref="EnsemblGenomes-Tr:CAB14540" /db_xref="InterPro:IPR020288" /db_xref="SubtiList:BG11290" /db_xref="UniProtKB/Swiss-Prot:P45934" /translation="MALSPEIEFEDIEDDSEVIETSQTYKIDFENGRITNEIITGLEA IKQFVYLSLHTERYAYSVYSHDIGNELQDVLADNETTDAYKKMEIPRLIEEALIYDDR ISAVTDFEIEKQGESFRVSFTVETDEGTLEIEEVLGEDV*" gene complement(2535961..2536386) /gene="yqbS" /locus_tag="BSU_25990" /old_locus_tag="BSU25990" CDS complement(2536399..2536662) /gene="yqbR" /locus_tag="BSU_26000" /old_locus_tag="BSU26000" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved phage protein of unknown function; skin element" /protein_id="NP_390477.1" /db_xref="EnsemblGenomes-Gn:BSU26000" /db_xref="EnsemblGenomes-Tr:CAB14541" /db_xref="InterPro:IPR022555" /db_xref="SubtiList:BG11289" /db_xref="UniProtKB/Swiss-Prot:P45933" /translation="MRLSEAIKHLAVRAVDSESPVDILPAEVVSVSPVEIRLNENDKL IIPADLIIVPKRLRAGEEALNTGERVMIVSLKGGQSFFILDKI*" gene complement(2536399..2536662) /gene="yqbR" /locus_tag="BSU_26000" /old_locus_tag="BSU26000" CDS complement(2536659..2537639) /gene="yqbQ" /locus_tag="BSU_26010" /old_locus_tag="BSU26010" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved phage protein of unknown function; skin element" /protein_id="NP_390478.1" /db_xref="EnsemblGenomes-Gn:BSU26010" /db_xref="EnsemblGenomes-Tr:CAB14542" /db_xref="SubtiList:BG11288" /db_xref="UniProtKB/Swiss-Prot:P45950" /translation="MIELFVIKETEWLELVTESVSLEGQRYQAPRSITAKIITKQGTH SYYSVSEGDTVLFKWKGKELFRGIVFSRNPEEHWMTFTAYDMLQYLVKNKDVYVFSNQ RADEIIKRLARDFQIPTTSIANTGYTIKSLVFKDDTSLYDMILKALKQTKSQTGRNYQ LYSAKGKLGLRAWPDLSEVWVLETGVNITGYQYSTSINDTATKVKLRRQKDNKTYTAT ASDSSGISKYGVLQYVETVSDNINQAQLQERAKVKQAQKKGVKKELKSIQAIGIPDLQ SGLPIYISIPEVGVKKTYWIDTDKHEFKGSTHTMTIDVVEKNSIPDGVSS*" gene complement(2536659..2537639) /gene="yqbQ" /locus_tag="BSU_26010" /old_locus_tag="BSU26010" CDS complement(2537652..2538311) /gene="yqbP" /locus_tag="BSU_26020" /old_locus_tag="BSU26020" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type s: structure" /codon_start=1 /transl_table=11 /product="putative phage murein-binding protein; skin element" /protein_id="NP_390479.1" /db_xref="EnsemblGenomes-Gn:BSU26020" /db_xref="EnsemblGenomes-Tr:CAB14543" /db_xref="InterPro:IPR018392" /db_xref="InterPro:IPR036779" /db_xref="SubtiList:BG11287" /db_xref="UniProtKB/Swiss-Prot:P45932" /translation="MTKSIYEFWISQGKDKLRLPVLPEQIDISNTIQNESVKVASFGE ITFIDKPGAKEISFSSFFPKKHSPLAEYKGFPSPENAIAKIEKWVKSKKPVQFLITGT KINLTCSIEVFSYTEGQKDIGDRDYEIKLKEYKTASPRKIKQKKKTKKKRPSKSAPKT YTVKKGDTLWDLAGKFYGDSTKWRKIWKVNKKAMIKRSKRNIRQPGHWIFPGQKLKIP Q*" gene complement(2537652..2538311) /gene="yqbP" /locus_tag="BSU_26020" /old_locus_tag="BSU26020" downshifts complement(2538128) /Source="Nicolas_upshifts" /id="D1343" /incds=1 /nref=1 /ntot=9 /MaxReadThrough="-0.00586999999999982" /MaxDrop="3.5543" /score="1.10121369" /energy="-11.3" /TU="NA" /idTUdmin="U2019" /TUdmin=5654 /isTUend="FALSE" misc_feature complement(2538189..2538197) /Source="Nicolas_upshift_promotors" /id="U2017" /multdbtbs="-" /comp="M20" /sig="Sig-" /pcomp="0.223776223776224" /psig="0.106893106893107" /xcortree=1518 /SigmaFactorBS="ccggtccttcctgaacaaattgatatatccaacacaattcaa aatgaatcagtaaaaGTGGCTAGTtttggggagatcacttttattgataaaccgggag c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(2538194) /Source="Nicolas_upshifts" /id="U2017" /multdbtbs="-" /comp="M20" /sig="Sig-" /pcomp="0.223776223776224" /psig="0.106893106893107" /xcortree=1518 /SigmaFactorBS="ccggtccttcctgaacaaattgatatatccaacacaattcaa aatgaatcagtaaaaGTGGCTAGTtttggggagatcacttttattgataaaccgggag c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" CDS complement(2538304..2543061) /gene="yqbO" /locus_tag="BSU_26030" /old_locus_tag="BSU26030" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 8760915, 8969508, 27824135; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative tape measure protein; skin element" /protein_id="NP_390480.2" /db_xref="EnsemblGenomes-Gn:BSU26030" /db_xref="EnsemblGenomes-Tr:CAB14544" /db_xref="InterPro:IPR008258" /db_xref="InterPro:IPR023346" /db_xref="SubtiList:BG11286" /db_xref="UniProtKB/Swiss-Prot:P45931" /translation="MAKLTATFELHDKISRKLRMIQGNAERLKRAANGPLIFEAEDRT ERVMRQIDRSANRLTARARLLEMGLDDRVSNGLHSIRQQAEDLTEGSHEVTVSVNDQA TPRFRLIRGGLTDLNSSHAEPTVSVRDHASNQLDEIRRHVTDVDSEHAEPTVSIKDRA SAALDAIEAKIDSLKGATITLAVAGGFSAGSIMGSGKSTMSQDAYVSATSNVNKKDVA KMTDQIYFNNKAGSSREEVSLSLRNLSQQTGASKKALAELTESSSKIAQLMNADQAEV DRAFSSMYNNLKLSGKQSGDLIAYVYRNAGDQADDLLDTMNEYSSTFKDLKLTGGQIA NAMIKGTKGGARNFDNLADSMREFNIRRTEMSDSQVDAFKTLFGAKETKKMFKGFKDG SISGEESLFRVAKALSKVKDKTKRAAIATELIGTQYEDLKQPILDMAEGIGTSAKTSG ELERSFTKLRDNNPMTPVNDAMRDFESISKDMGTSLLTGLGPAFDKISSFINSKEGQE KLKEIKKDIADLGEEIGDKLNVAIEWSVNHWDDLKTAIKVVIPSLIGLIGYLKILRPL LKGIGTVGSDAAGVIRKLIPKRTPKAGTNTQSERRNRNSNRNASTRGRESKTATGPTS LPRSGSLTYCCCSDGGKNDRIRRRRGKRVLGRRGNPNRMNPSDSSIAVSSERLERRRS GRTVGTNPTRDSRSAIITTRSELYSAGRAAGGTSKFGKVLSPLKSVGKFAKGVPLLGT ALAATDLIGMNKDNVGEKIGSAGGGLAGAATGAAIGSVIPGVGTAIGGLVGGIAGTMG GSSLGKAFDGSEVKKKLNSTLFDQKWWSEKWSGIKSNAKTSINGLSDTWSNVKEKVKS TLFNSEWWSEKWSGVKSWAQNKWNSASSVWESVKGKIKSTLFSEKWWSGKWEGVKSWA QSKWDSASSVWQSVKGKLKSTLFSEKWWSGKWESVKSWSKNKWDNAKSIWKSVKSSIS ETLFSKKWWSEKWQSVKELGSSILGGVKEVGGKVASSAKKTAGKAWGYVKSGVNYLFG SGKEKPKKHATGGYITKPTISWIGEAGKEFVIPVENNKGRGKMLLSQAASKLGMSVVD DIASASSAGGEPATSPLVRSAAVTASVSPIIDTSSLDEQATSFGQQFTKSFDQGIRDN VVSMEAWKQKNVGQPMNNLISYSPNYGKQVVNGYAKGQNSTSTGTDGFLQTKVKMPFQ NTVNKSSSWGSGTIKGFASGQNSSQTGTDQYVSTHINKPFIRSKESSNGWGSGMIGNF VSGMTSKASEVNEAAKELAKKVEKAFREELDIHSPSRVMMSLGRFASIGIVKGLDSVD VKKFAEKQAGSLAAAYSGMGAVSGNVKQWLMAAIMATKTPMSWLPGLMTIAQHESGGN PKAINLWDSNAKAGHPSQGLMQTIPSTFNAHKLPGMNNILNPIHNAAAAIGYIKSRYG SINNVPGIRSMRHGGPYVGYANGGLITKEQIARVGEGNKREWIIPEERGIRGRYLLAQ AAKALGMEVTDPSEKGQTELSSGQVTAATTGRNQTTFKAAGGKEVIIQFNGDQHFHND QDMNSLVAKIKQALVDELEQDINIGTKGVVAFD*" gene complement(2538304..2543061) /gene="yqbO" /locus_tag="BSU_26030" /old_locus_tag="BSU26030" CDS complement(2543064..2543255) /gene="yqbNc" /locus_tag="BSU_26039" /old_locus_tag="BSU26039" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /pseudo /codon_start=1 /transl_table=11 /product="conserved unknown protein (fragment); skin element; C-terminal part of YqbN" /db_xref="SubtiList:BG11285" /translation="SKKLVKDGDKEAVYLYYAMHELKYAPSELRELYEAPKAFKALLY GLIGFKLELLEKEAKKGGN*" gene complement(2543064..2543255) /gene="yqbNc" /locus_tag="BSU_26039" /old_locus_tag="BSU26039" /pseudo CDS complement(2543243..2543692) /gene="yqbNn" /locus_tag="BSU_26040" /old_locus_tag="BSU26040" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function; PubMedId: 8760915, 8969508" /pseudo /codon_start=1 /transl_table=11 /product="conserved unknown protein (fragment); skin element; N-terminal part of YqbN" /translation="MSEKQNEKVYDLSFFMPGQTIEAEEVEVPISKRFVDKEGNVVPF IFKAITTERIDELEKENTTYKNVKGRGRVKELDSQRFYARIAVETTVYPNFKAKELRE AYKTEDPVEVAKRVLSVGGEYANWLNKAIEINGFDDDLEDLEEAAKN*" gene complement(2543243..2543692) /gene="yqbNn" /locus_tag="BSU_26040" /old_locus_tag="BSU26040" /pseudo downshifts complement(2543584) /Source="Nicolas_upshifts" /id="D1344" /incds=1 /nref=1 /ntot=1 /MaxReadThrough="0.0885900000000008" /MaxDrop="2.00139" /score="22.4743207" /energy="-11.1" /TU="NA" /idTUdmin="U2019" /TUdmin=198 /isTUend="FALSE" promotor_-35 2543755..2543758 /Source="Nicolas_upshift_promotors" /id="U2018" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.752247752247752" /psig="0.997002997002997" /xcortree=2856 /SigmaFactorBS="ttttagttttggacaagaaaaaaagcacattcatactttttg AATGtgctttccatataaTTCATGTATAATAGATTCTTgaagctaccttagcttatcc t" /listShort="yqdB, S978, S979" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2543773..2543792 /Source="Nicolas_upshift_promotors" /id="U2018" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.752247752247752" /psig="0.997002997002997" /xcortree=2856 /SigmaFactorBS="ttttagttttggacaagaaaaaaagcacattcatactttttg AATGtgctttccatataaTTCATGTATAATAGATTCTTgaagctaccttagcttatcc t" /listShort="yqdB, S978, S979" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2543773 /Source="Nicolas_upshifts" /id="U2018" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.752247752247752" /psig="0.997002997002997" /xcortree=2856 /SigmaFactorBS="ttttagttttggacaagaaaaaaagcacattcatactttttg AATGtgctttccatataaTTCATGTATAATAGATTCTTgaagctaccttagcttatcc t" /listShort="yqdB, S978, S979" /GFF_Attribute="listLong" CDS 2543838..2544017 /gene="txpA" /locus_tag="BSU_26050" /old_locus_tag="BSU26050" /function="17.2: Prophage functions" /experiment="publication(s) with functional evidences, PMID:16166525, 23300471, 27450630" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16166525, 23300471, 27450630; Product type f: factor" /codon_start=1 /transl_table=11 /product="toxic peptide of toxin-antitoxin system; skin element" /protein_id="NP_390482.1" /db_xref="EnsemblGenomes-Gn:BSU26050" /db_xref="EnsemblGenomes-Tr:CAB14546" /db_xref="GOA:P54373" /db_xref="SubtiList:BG11512" /db_xref="UniProtKB/Swiss-Prot:P54373" /translation="MSTYESLMVMIGFANLIGGIMTWVISLLTLLFMLRKKDTHPIYI TVKEKCLHEDPPIKG*" gene 2543838..2544017 /gene="txpA" /locus_tag="BSU_26050" /old_locus_tag="BSU26050" downshifts 2543939 /Source="Nicolas_upshifts" /id="D1345" /incds=1 /nref=7 /ntot=107 /MaxReadThrough="3.91957" /MaxDrop="3.54148" /score="3.89495031" /energy="-11.4" /TU="U2018" /idTUdmin="U2020" /TUdmin="-867" /isTUend="FALSE" misc_RNA complement(2543941..2544163) /gene="ratA" /locus_tag="BSU_misc_RNA_81" /product="antisense RNA controlling synthesis of TxpA, membrane associated toxin of a toxin antitoxin system; skin element" /experiment="publication(s) with functional evidences, PMID:16166525, 18948176, 23300471" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16166525, 18948176, 23300471; Product type n: RNA" /function="17.2: Prophage functions" gene complement(2543941..2544163) /gene="ratA" /locus_tag="BSU_misc_RNA_81" S_feature complement(2543960..2544175) /Source="Nicolas_S_feature" /locus_tag="new_2678362_2678577_c" /HighExp="BC, B60, M9-stat, Lbstat, Sw, LPhT, HPh, Etha, BT, S2" /AntisenseName="yqdB" /AntisenseCor="0.425939075311497" /AntisenseRegPval="-12.6" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="1, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S976" downshifts complement(2544003) /Source="Nicolas_upshifts" /id="D1346" /incds=0 /nref=235 /ntot=269 /MaxReadThrough="4.02751" /MaxDrop="6.00843" /score="16.3983079" /energy="-17.8" /TU="U2019" /idTUdmin="U2021" /TUdmin=21 /isTUend="TRUE" promotor_-10 complement(2544160..2544179) /Source="Nicolas_upshift_promotors" /id="U2019" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.988011988011988" /psig=1 /xcortree=3094 /SigmaFactorBS="tagataaaaaaagtaacaaataaaagatacaaataattATAT AATcaatatatattCATGTTATAATGGTGCCAAGcaaaagtattgcaactactggcgt a" /listShort="S976" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2544175) /Source="Nicolas_upshifts" /id="U2019" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.988011988011988" /psig=1 /xcortree=3094 /SigmaFactorBS="tagataaaaaaagtaacaaataaaagatacaaataattATAT AATcaatatatattCATGTTATAATGGTGCCAAGcaaaagtattgcaactactggcgt a" /listShort="S976" /GFF_Attribute="listLong" S_feature complement(2544177..2544684) /Source="Nicolas_S_feature" /locus_tag="new_2678579_2679086_c" /HighExp="Cold, G135, S8, M0t90, LPhT, G180, Lbtran, S4, C30, M0t45" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigB" /TUshortPSig="1, 0.968" /TUlongSig="NA" /TUlongPSig="NA" /label="S977" promotor_-35 complement(2544191..2544197) /Source="Nicolas_upshift_promotors" /id="U2019" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.988011988011988" /psig=1 /xcortree=3094 /SigmaFactorBS="tagataaaaaaagtaacaaataaaagatacaaataattATAT AATcaatatatattCATGTTATAATGGTGCCAAGcaaaagtattgcaactactggcgt a" /listShort="S976" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 2544293..2544300 /Source="Nicolas_upshift_promotors" /id="U2020" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.947052947052947" /psig="0.999000999001" /xcortree=471 /SigmaFactorBS="agccttaaccctttttcttttattaaaaaccCTCGGATTatg aaagtgtTATGGTACAATATGGTTTAGtataaatgaatattggctttcaacatctcaa g" /listShort="S978, S979" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2544311..2544330 /Source="Nicolas_upshift_promotors" /id="U2020" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.947052947052947" /psig="0.999000999001" /xcortree=471 /SigmaFactorBS="agccttaaccctttttcttttattaaaaaccCTCGGATTatg aaagtgtTATGGTACAATATGGTTTAGtataaatgaatattggctttcaacatctcaa g" /listShort="S978, S979" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 2544322..2544541 /Source="Nicolas_S_feature" /locus_tag="new_2678724_2678943" /HighExp="B60, BT, M9-stat, BC, T1.30H, B36, T2.0H, T0.30H, S8, Gly" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.99046900000000004" /TUshortSig="SigA, SigA" /TUshortPSig="0.999, 0.997" /TUlongSig="NA" /TUlongPSig="NA" /label="S978" upshifts 2544322 /Source="Nicolas_upshifts" /id="U2020" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.947052947052947" /psig="0.999000999001" /xcortree=471 /SigmaFactorBS="agccttaaccctttttcttttattaaaaaccCTCGGATTatg aaagtgtTATGGTACAATATGGTTTAGtataaatgaatattggctttcaacatctcaa g" /listShort="S978, S979" /GFF_Attribute="listLong" CDS 2544397..2544486 /gene="bsrH" /locus_tag="BSU_26055" /old_locus_tag="BSU26055" /experiment="publication(s) with functional evidences, PMID:23059907, 23300471, 24576839" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 23059907, 23300471, 24576839; Product type f: factor" /codon_start=1 /transl_table=11 /product="skin region; type I toxin" /protein_id="YP_009513980.1" /translation="MHVSTFQALMLMLAFGSFIIALLTYIKKK*" gene 2544397..2544486 /gene="bsrH" /locus_tag="BSU_26055" /old_locus_tag="BSU26055" misc_RNA complement(2544474..2544612) /gene="asrH" /locus_tag="BSU_misc_RNA_92" /product="antitoxin RNA" /experiment="publication(s) with functional evidences, PMID:23059907, 23300471, 24576839" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 23059907, 23300471, 24576839; Product type n: RNA" gene complement(2544474..2544612) /gene="asrH" /locus_tag="BSU_misc_RNA_92" downshifts 2544498 /Source="Nicolas_upshifts" /id="D1347" /incds=0 /nref=1 /ntot=25 /MaxReadThrough="6.08901" /MaxDrop="3.1963" /score="15.4220162" /energy="-11.5" /TU="U2018,U2020" /idTUdmin="U2020" /TUdmin="-308" /isTUend="FALSE" downshifts 2544564 /Source="Nicolas_upshifts" /id="D1348" /incds=0 /nref=16 /ntot=140 /MaxReadThrough="3.52603" /MaxDrop="5.25491" /score="15.4220162" /energy="-11.5" /TU="U2018,U2020" /idTUdmin="U2020" /TUdmin="-242" /isTUend="FALSE" S_feature 2544609..2544980 /Source="Nicolas_S_feature" /locus_tag="new_2679011_2679382" /HighExp="Cold, LoTm, LPhT, S8, C30, Glu, T-0.40H, M/G, GM 25, T2.0H" /AntisenseName="yqbM" /AntisenseCor="-0.170707368814771" /AntisenseRegPval="-2.2999999999999998" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="0.999, 0.997" /TUlongSig="NA" /TUlongPSig="NA" /label="S979" misc_feature complement(2544671..2544690) /Source="Nicolas_upshift_promotors" /id="U2021" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.95104895104895" /psig=1 /xcortree=3098 /SigmaFactorBS="tctaatcactttcacgaaaaatcgccgactttaacgaagata tttacgaaaaaaTGTGGTAAGATTACTTTAGAagtaattcaaccgtaccaaatggaaa c" /listShort="S977, S976" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(2544684) /Source="Nicolas_upshifts" /id="U2021" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.95104895104895" /psig=1 /xcortree=3098 /SigmaFactorBS="tctaatcactttcacgaaaaatcgccgactttaacgaagata tttacgaaaaaaTGTGGTAAGATTACTTTAGAagtaattcaaccgtaccaaatggaaa c" /listShort="S977, S976" /GFF_Attribute="listLong" CDS complement(2544740..2545183) /gene="yqbM" /locus_tag="BSU_26060" /old_locus_tag="BSU26060" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 8760915, 8969508, 25525268, 26909579; Product type s: structure" /codon_start=1 /transl_table=11 /product="putative tail tube protein; skin element" /protein_id="NP_390483.2" /db_xref="EnsemblGenomes-Gn:BSU26060" /db_xref="EnsemblGenomes-Tr:CAB14547" /db_xref="InterPro:IPR018989" /db_xref="SubtiList:BG11284" /db_xref="UniProtKB/Swiss-Prot:P45929" /translation="MALKAQNTISGKEGRLFLDGEEMAHIKTFEANVEKNKSEVNIMG RRMTGHKTTGANGTGTATFYKVTSQFVLIMMDYVKKGSDPYFTLQAVLDDASSGRGTE RVTLYDVNFDSAKIAGLDVDSEALEEEVPFTFEDFDVPEQLKSTF*" gene complement(2544740..2545183) /gene="yqbM" /locus_tag="BSU_26060" /old_locus_tag="BSU26060" CDS complement(2545186..2546586) /gene="yqbK" /locus_tag="BSU_26075" /old_locus_tag="BSU26075" /function="17.2: Prophage functions" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type s: structure" /codon_start=1 /transl_table=11 /product="putative phage tail sheath protein; skin element" /protein_id="NP_390485.2" /db_xref="EnsemblGenomes-Gn:BSU26075" /db_xref="EnsemblGenomes-Tr:CAB14549" /db_xref="InterPro:IPR020287" /db_xref="InterPro:IPR035089" /db_xref="InterPro:IPR035326" /db_xref="SubtiList:BG11282" /db_xref="UniProtKB/Swiss-Prot:P45927" /translation="MNGGTFTPGKEKERAGIYFNFKTTAENRVSAGERGTVALPIASS WGEVKKFISISSIEDLNKKVGLNIDDPSLLLLREAMKKANTVLLYRLTEGLRASADIS EGVKATALYGGTKGNDIIISITENVIDSSKVDVTTYLDQSEVDKQTVSKAEELKPNKY VTFTGKGDLTVTIPLTGTAPEDVSGALPATSGIRLSGGTDKTPTNADYTAFLEAAETE YFDTIALPVEDNEQLKATFVAFIKRLRDNQGQKVQGVLSNYKGDHEGIINVTGGVLLE DGTEITPEKATAWVAGASAGATFNQSLTFVEYEGAVDVLNRIDNDEIVERLSNGEFLF TYDSRDKSVSVEKDINSLTSLTAEKNKMFQKNKIVRVLDAINNDLTSQLKALIKSRKA SGSDVPATNDGLQFVKTLITQYLSVLQDNEGITDFDSENDITIALNNDRDGFLIDLAV QPVDAAEKFYFNVEVK*" gene complement(2545186..2546586) /gene="yqbK" /locus_tag="BSU_26075" /old_locus_tag="BSU26075" promotor_-10 complement(2545777..2545795) /Source="Nicolas_upshift_promotors" /id="U2022" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.968031968031968" /psig="0.968031968031968" /xcortree=155 /SigmaFactorBS="caagggcaaaaggttcaaggtgttctttcAAATTACaaggga gaccatgaGGGTATTATCAATGTAACAggtggtgtcctacttgaggatggaacggaga t" /listShort="yqbM, S977" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2545785) /Source="Nicolas_upshifts" /id="U2022" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.968031968031968" /psig="0.968031968031968" /xcortree=155 /SigmaFactorBS="caagggcaaaaggttcaaggtgttctttcAAATTACaaggga gaccatgaGGGTATTATCAATGTAACAggtggtgtcctacttgaggatggaacggaga t" /listShort="yqbM, S977" /GFF_Attribute="listLong" promotor_-35 complement(2545810..2545816) /Source="Nicolas_upshift_promotors" /id="U2022" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.968031968031968" /psig="0.968031968031968" /xcortree=155 /SigmaFactorBS="caagggcaaaaggttcaaggtgttctttcAAATTACaaggga gaccatgaGGGTATTATCAATGTAACAggtggtgtcctacttgaggatggaacggaga t" /listShort="yqbM, S977" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2546587..2546778) /gene="yqzN" /locus_tag="BSU_26089" /old_locus_tag="BSU26089" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved phage protein of unknown function; skin element" /protein_id="YP_003097763.1" /db_xref="EnsemblGenomes-Gn:BSU26089" /db_xref="EnsemblGenomes-Tr:CAX52664" /db_xref="UniProtKB/Swiss-Prot:C0H454" /translation="MMATKKEKAENAFYIKDLREHSRELFGVKPEVFDGALFHVHKMS ITKSEAKKLISQFLQKEVK*" gene complement(2546587..2546778) /gene="yqzN" /locus_tag="BSU_26089" /old_locus_tag="BSU26089" CDS complement(2546775..2547212) /gene="yqbJ" /locus_tag="BSU_26090" /old_locus_tag="BSU26090" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved phage protein of unknown function; skin element" /protein_id="NP_390486.2" /db_xref="EnsemblGenomes-Gn:BSU26090" /db_xref="EnsemblGenomes-Tr:CAB14550" /db_xref="SubtiList:BG11281" /db_xref="UniProtKB/Swiss-Prot:P45926" /translation="MNQEVGSIMGYLYKLYPVQVYEEEIPQDFAVPSLYFPPASTVDG VDTVSTFQKAYVLNVKLFHENVQKAHNEAERIADTLRSRRGIIPLIQESGEDTGDFIR LSRIETRVSDDYATIVLNWTSRYWYEREDQRSIDGFKFKSGVK*" gene complement(2546775..2547212) /gene="yqbJ" /locus_tag="BSU_26090" /old_locus_tag="BSU26090" CDS complement(2547225..2547728) /gene="yqbI" /locus_tag="BSU_26100" /old_locus_tag="BSU26100" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type s: structure" /codon_start=1 /transl_table=11 /product="putative phage tail component; skin element" /protein_id="NP_390487.1" /db_xref="EnsemblGenomes-Gn:BSU26100" /db_xref="EnsemblGenomes-Tr:CAB14551" /db_xref="InterPro:IPR010064" /db_xref="SubtiList:BG11280" /db_xref="UniProtKB/Swiss-Prot:P45925" /translation="MKIRGLDQFIQSLDRASRGGLKRKYEQWLESMGFEFLDIIQDEI IRTKTVDTRRLLNSFQKGDQDNIFSMTEGSLKLDVGTNLDYASYVNDGHFTIDPSKNQ DRRWVPGRWKGDRFEYDPAEKNSGMLLKFRWVDGSGFWDNAMAIFQLMFERSLERKLQ QWIYEEF*" gene complement(2547225..2547728) /gene="yqbI" /locus_tag="BSU_26100" /old_locus_tag="BSU26100" CDS complement(2547725..2548087) /gene="yqbH" /locus_tag="BSU_26110" /old_locus_tag="BSU26110" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved phage protein of unknown function; skin element" /protein_id="NP_390488.1" /db_xref="EnsemblGenomes-Gn:BSU26110" /db_xref="EnsemblGenomes-Tr:CAB14552" /db_xref="InterPro:IPR024556" /db_xref="SubtiList:BG11279" /db_xref="UniProtKB/Swiss-Prot:P45924" /translation="MSYQSLLTHRCDIYHLQEKKENRKQKFGVPVEDVQPVFSYPDEP DIENQPCYFTEKSQSIIQQESNVSIYQSFLVHFPATADIRVNDRAVWDGTAYKLQKPR KIRNHHWEVTAVREVEYL*" gene complement(2547725..2548087) /gene="yqbH" /locus_tag="BSU_26110" /old_locus_tag="BSU26110" CDS complement(2548084..2548479) /gene="yqbG" /locus_tag="BSU_26120" /old_locus_tag="BSU26120" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved phage protein of unknown function; skin element" /protein_id="NP_390489.2" /db_xref="EnsemblGenomes-Gn:BSU26120" /db_xref="EnsemblGenomes-Tr:CAB14553" /db_xref="InterPro:IPR013514" /db_xref="InterPro:IPR036558" /db_xref="PDB:1XN8" /db_xref="PDB:1ZTS" /db_xref="SubtiList:BG11278" /db_xref="UniProtKB/Swiss-Prot:P45923" /translation="MLLITPDELKSYSVFESVKTRPDELLKQDILEATADIILKVGHD FSDAEYIPLPETVRLALLKLSQFYALINGDESIIKGYTTEKIGDYSYTLGDGSSLQKP DVYALIKDYVKPADPDLEGIEAKVRMRSI*" gene complement(2548084..2548479) /gene="yqbG" /locus_tag="BSU_26120" /old_locus_tag="BSU26120" CDS complement(2548483..2548794) /gene="yqbF" /locus_tag="BSU_26130" /old_locus_tag="BSU26130" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein; skin element" /protein_id="NP_390490.1" /db_xref="EnsemblGenomes-Gn:BSU26130" /db_xref="EnsemblGenomes-Tr:CAB14554" /db_xref="InterPro:IPR027926" /db_xref="InterPro:IPR036269" /db_xref="InterPro:IPR036840" /db_xref="PDB:2HJQ" /db_xref="SubtiList:BG11277" /db_xref="UniProtKB/Swiss-Prot:P45922" /translation="MFTAKLIKGKTYNVMGITFRAGVSQTVPKKLYEYLNENPYFILT QELNNQKDDPINYTESELKGMNKAEHESIISNLGRNPSDFKNADERIAYILKQIDNKG E*" gene complement(2548483..2548794) /gene="yqbF" /locus_tag="BSU_26130" /old_locus_tag="BSU26130" promotor_-10 complement(2548618..2548636) /Source="Nicolas_upshift_promotors" /id="U2023" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=2847 /SigmaFactorBS="tttaaatgaaaatccatattttatactaacccaagagCTTAA TAAtcaaaaggatgaTCCGATAAATTATACTGAAtcggaattgaaaggtatgaataaa g" /listShort="yqbG" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2548633) /Source="Nicolas_upshifts" /id="U2023" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=2847 /SigmaFactorBS="tttaaatgaaaatccatattttatactaacccaagagCTTAA TAAtcaaaaggatgaTCCGATAAATTATACTGAAtcggaattgaaaggtatgaataaa g" /listShort="yqbG" /GFF_Attribute="listLong" promotor_-35 complement(2548649..2548656) /Source="Nicolas_upshift_promotors" /id="U2023" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=2847 /SigmaFactorBS="tttaaatgaaaatccatattttatactaacccaagagCTTAA TAAtcaaaaggatgaTCCGATAAATTATACTGAAtcggaattgaaaggtatgaataaa g" /listShort="yqbG" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2548805..2549740) /gene="yqbE" /locus_tag="BSU_26140" /old_locus_tag="BSU26140" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type s: structure" /codon_start=1 /transl_table=11 /product="putative phage capsid protein; skin element" /protein_id="NP_390491.2" /db_xref="EnsemblGenomes-Gn:BSU26140" /db_xref="EnsemblGenomes-Tr:CAB14555" /db_xref="InterPro:IPR024455" /db_xref="SubtiList:BG11276" /db_xref="UniProtKB/Swiss-Prot:P45921" /translation="MRNQEVINKAEMTLSTLESGGIMNPTQASTFIRMVQDTPTILRD ARVIQMDHDTQKIEKIGFGQRILRAAQEGVALTKDQKSVPSTSTVNLSTKEVIAEVNI TYDTLENNIEKDGLQNTIMQMIAERAAVDIEELLVNGDTSSSDSYLAQLDGIRKQATS HIVDAAGEELTRQTFKRGYKAVPPKYLRIPQEFRFYTSPGIEVEWKDRVADRQTNLGD AAVQGGLSSAFGVPIKGIANLQPYTIGEGDTAADVSDIILTHPKNIILGFSRNIRIEV DKDIRRRMFIIVLTAKLDSVFEEEDAVAKIVKVKE*" gene complement(2548805..2549740) /gene="yqbE" /locus_tag="BSU_26140" /old_locus_tag="BSU26140" CDS complement(2549759..2550727) /gene="yqbD" /locus_tag="BSU_26150" /old_locus_tag="BSU26150" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative nucleic acid-binding protein; skin element" /protein_id="NP_390492.2" /db_xref="EnsemblGenomes-Gn:BSU26150" /db_xref="EnsemblGenomes-Tr:CAB14556" /db_xref="GOA:P45920" /db_xref="InterPro:IPR027924" /db_xref="SubtiList:BG11275" /db_xref="UniProtKB/Swiss-Prot:P45920" /translation="MPRELVNAKITHVSYVDKAANQKQFFIVKSEKQPDFQKEVRILA KEADEQKLVYGIVYEPDTVDAHGDFMTAAEIEKAAHGFLKDARQIDKQHDFQGGVGEV VESYVAPADFEMNGETIKKGSWVLVTKASEEVWEQIKKGEITGYSMAGTAETIEKQEK PVSQEKTDEKGLFNLLKNFFVGKQQQSYEEPVAKAGRKFSASNLQEIKNAHAALGNLL SQVETKEGEEEMTSEEVTKSIQEALEPIKKRLETLEKEEELNKKDKEKEEETEKEGEK LKKAISEAVQPLADRIEAIEKSRGTSKQTEESGSEQVQKSIWSGLF*" gene complement(2549759..2550727) /gene="yqbD" /locus_tag="BSU_26150" /old_locus_tag="BSU26150" downshifts complement(2549899) /Source="Nicolas_upshifts" /id="D1349" /incds=1 /nref=2 /ntot=11 /MaxReadThrough="0.90521" /MaxDrop="4.11085" /score="3.63408171" /energy="-7.7" /TU="NA" /idTUdmin="U2025" /TUdmin=902 /isTUend="FALSE" promotor_no_box complement(2549925..2550025) /Source="Nicolas_upshift_promotors" /id="U2024" /multdbtbs="-" /comp="M21" /sig="Sig-" /pcomp="0.55044955044955" /psig="0.030969030969031" /xcortree=1491 /SigmaFactorBS="gtaactaaatccattcaagaagcattagagccaattaagaag cggctcgagacattagaaaaagaggaagagcttaataagaaagataaagaaaaagaag a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_no_box" upshifts complement(2549965) /Source="Nicolas_upshifts" /id="U2024" /multdbtbs="-" /comp="M21" /sig="Sig-" /pcomp="0.55044955044955" /psig="0.030969030969031" /xcortree=1491 /SigmaFactorBS="gtaactaaatccattcaagaagcattagagccaattaagaag cggctcgagacattagaaaaagaggaagagcttaataagaaagataaagaaaaagaag a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" downshifts 2550043 /Source="Nicolas_upshifts" /id="D1350" /incds=1 /nref=2 /ntot=27 /MaxReadThrough="-0.23511" /MaxDrop="3.95319" /score="-9.87607" /energy="-6.4" /TU="NA" /idTUdmin="U2018" /TUdmin=5105 /isTUend="FALSE" CDS complement(2550760..2551413) /gene="yqbC" /locus_tag="BSU_26160" /old_locus_tag="BSU26160" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved phage protein of unknown function; skin element" /protein_id="NP_390493.1" /db_xref="EnsemblGenomes-Gn:BSU26160" /db_xref="EnsemblGenomes-Tr:CAB14557" /db_xref="GOA:P45919" /db_xref="SubtiList:BG11274" /db_xref="UniProtKB/Swiss-Prot:P45919" /translation="MNWMEFISSIVKSIIWPVAIIILVFKLKQPVSNLISTLAKIKYK DWEFEFTIDQKLDKISFQLNKENQYGTDDQNLKDSLNLESNSEITEETHSHYNEKTSI KGDNDLLLKMEMIRLYGAVKNLYEKVSEKDDAADKSQGIGMLYMVDYLKRHKILNDSF AESLLDIMNIVHDLEKSHISQSYIMNKFFWNVDKSVKRLMEITSNYVAENTAGETSN* " gene complement(2550760..2551413) /gene="yqbC" /locus_tag="BSU_26160" /old_locus_tag="BSU26160" downshifts complement(2550801) /Source="Nicolas_upshifts" /id="D1351" /incds=0 /nref=89 /ntot=228 /MaxReadThrough="2.10348" /MaxDrop="4.01141" /score="3.63408171" /energy="-7.7" /TU="NA" /idTUdmin="U2025" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(2551432..2551451) /Source="Nicolas_upshift_promotors" /id="U2025" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.973026973026973" /psig="0.995004995004995" /xcortree=2296 /SigmaFactorBS="agaaaaagaagagattcaaagagaagTCTTAGCAaacatgga ataaaaTAGTATAATGTCCTCATTACatattaggtggggaaaatatgaattggatgga g" /listShort="yqbC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2551439) /Source="Nicolas_upshifts" /id="U2025" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.973026973026973" /psig="0.995004995004995" /xcortree=2296 /SigmaFactorBS="agaaaaagaagagattcaaagagaagTCTTAGCAaacatgga ataaaaTAGTATAATGTCCTCATTACatattaggtggggaaaatatgaattggatgga g" /listShort="yqbC" /GFF_Attribute="listLong" CDS complement(2551454..2552371) /gene="yqbB" /locus_tag="BSU_26170" /old_locus_tag="BSU26170" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type s: structure" /codon_start=1 /transl_table=11 /product="putative phage head morphogenesis protein; skin element" /protein_id="NP_390494.1" /db_xref="EnsemblGenomes-Gn:BSU26170" /db_xref="EnsemblGenomes-Tr:CAB14558" /db_xref="InterPro:IPR006528" /db_xref="SubtiList:BG11273" /db_xref="UniProtKB/Swiss-Prot:P45918" /translation="MNKTDKLLESLNVFIQKAEENQYKQLGEMVPDFPGKSNIPKYVE EYEKGIARLLRRQHKKFLDGLKGFVSKDSEETLKALLVFFTQNLFAEDDFEEEFQELT EGFLQQTIEEMAEVIMDSIDPEVPFKVLSNRTINWIKDWSKKLAEIMKLNTHEVVEDV LTNAIENGSSIQDIELTLKDMPQFDRERARTTAITEVLAASSAAQHESYAQSPAVKKK KWRHSGGKKNNPRENHIDLDGTVIGVDEEFQIPGSSETCMFPRDPKLSTRERVNCHCV LSPVVDSKILGLSPEEKEEIQREVLANME*" gene complement(2551454..2552371) /gene="yqbB" /locus_tag="BSU_26170" /old_locus_tag="BSU26170" promotor_-35 complement(2551466..2551473) /Source="Nicolas_upshift_promotors" /id="U2025" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.973026973026973" /psig="0.995004995004995" /xcortree=2296 /SigmaFactorBS="agaaaaagaagagattcaaagagaagTCTTAGCAaacatgga ataaaaTAGTATAATGTCCTCATTACatattaggtggggaaaatatgaattggatgga g" /listShort="yqbC" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2552368..2553900) /gene="yqbA" /locus_tag="BSU_26180" /old_locus_tag="BSU26180" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type s: structure" /codon_start=1 /transl_table=11 /product="putative phage capsid protein; skin element" /protein_id="NP_390495.1" /db_xref="EnsemblGenomes-Gn:BSU26180" /db_xref="EnsemblGenomes-Tr:CAB14559" /db_xref="InterPro:IPR006430" /db_xref="InterPro:IPR006944" /db_xref="InterPro:IPR016753" /db_xref="SubtiList:BG11272" /db_xref="UniProtKB/Swiss-Prot:P45917" /translation="MSKKSVKARVIKASPPTESTKQIYEDEFADSYDSNILPPPYNLK ELKMIAEYSTILQQCVDAYRTNIVGFGFDFEYSFDVNSPDVTNEEKTEAESEWTKLEE FVKYLHFDESAETLLGFVIEDREKTGNGFIEVIRNGENKPAGIEYMDVQNVRVCKLSE PIEVDFTYFEQGQMKSIKREKRFRKYVQMIDGRMVYFKEYGDPRTLNLETGQYDEQTP LEKRANEVVHFKIGSGIYGKPRWIGHIVNLYGARKAEELNFMYFKQGRHIPAAITIEN GMLSEDSYTQLQDYMNGLEGVENAHKFLLLEAEGIAKGKNIHGDEEIAPVKVDIKSLA EILQEDALFLEYDQKNRDKIRSAFRLPPLYTGEAQDYNRATADTARKITEEQVFQPER KLITGKLNALFLNDLEIHKVRLQLKGPDFRDPLEIAKVLTPFITAGAVSPNDLRDLAG RVLGKTLEEWPEEEYNRPLGKTNESSVSDPLAALFKSKNGTPNMIGLLKDMRDVLEDL KR*" gene complement(2552368..2553900) /gene="yqbA" /locus_tag="BSU_26180" /old_locus_tag="BSU26180" promotor_-10 complement(2553768..2553783) /Source="Nicolas_upshift_promotors" /id="U2026" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp="0.996003996003996" /psig="0.996003996003996" /xcortree=1679 /SigmaFactorBS="tatgaagatgaatttgctgacagctaTGACAGCAATattttg cctcctCCGTATAACCTAAAGGaattaaaaatgattgctgagtattcaacaatcttac a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2553771) /Source="Nicolas_upshifts" /id="U2026" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp="0.996003996003996" /psig="0.996003996003996" /xcortree=1679 /SigmaFactorBS="tatgaagatgaatttgctgacagctaTGACAGCAATattttg cctcctCCGTATAACCTAAAGGaattaaaaatgattgctgagtattcaacaatcttac a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(2553796..2553805) /Source="Nicolas_upshift_promotors" /id="U2026" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp="0.996003996003996" /psig="0.996003996003996" /xcortree=1679 /SigmaFactorBS="tatgaagatgaatttgctgacagctaTGACAGCAATattttg cctcctCCGTATAACCTAAAGGaattaaaaatgattgctgagtattcaacaatcttac a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2553904..2555199) /gene="yqaT" /locus_tag="BSU_26190" /old_locus_tag="BSU26190" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative phage-related terminase large subunit; skin element" /protein_id="NP_390496.1" /db_xref="EnsemblGenomes-Gn:BSU26190" /db_xref="EnsemblGenomes-Tr:CAB14560" /db_xref="GOA:P45916" /db_xref="InterPro:IPR006437" /db_xref="InterPro:IPR035412" /db_xref="InterPro:IPR035413" /db_xref="SubtiList:BG11271" /db_xref="UniProtKB/Swiss-Prot:P45916" /translation="MIKQVNPHFKEFLFDWNQKFQFLVGGYGSSKSYHVALKIVLKLL REKRTALVIREVYDTHRDSTFSLFDELVSDLKLDHIVRCVSSPMQIRFSNGSRIIFKG MDKPAKLKSINNISLIWIEECSEVKYEGFKELLGRLRHPTLPLHMILSTNPVGEDNWT FKHFFKDDREKRFVLDDKELYEKRIIVSNDTYYHHSTADDNLFLPESYVQQLEELKEY DPDLYRIARKGHFGVNGIRVLPQFEERPHEEVMTAISNINRPLKRVGMDFGFVESYNA VVRVAVDHEKKYLYIYWEYYKNGLTDDKTAEELKEFAETKELIKADSAEPKTIRYFQQ HGFNMVGARKYQGSRLQYTKKIKRFRKIICSDRCENTIYELKPLAYATDKLGNIIEDE FTIDPHTLSAIWYALDDYEVTDLKEESKGRPQRSRPGRR*" gene complement(2553904..2555199) /gene="yqaT" /locus_tag="BSU_26190" /old_locus_tag="BSU26190" CDS complement(2555192..2555911) /gene="yqaS" /locus_tag="BSU_26200" /old_locus_tag="BSU26200" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative phage-related terminase small subunit; skin element" /protein_id="NP_390497.1" /db_xref="EnsemblGenomes-Gn:BSU26200" /db_xref="EnsemblGenomes-Tr:CAB14561" /db_xref="InterPro:IPR018925" /db_xref="SubtiList:BG11270" /db_xref="UniProtKB/Swiss-Prot:P45915" /translation="MVDKHIQAYKDYAKGMKYKDLAEKYGVSVNTIKSWKQRHGWQRK KGAPLKKGVHTKKVGAPLGNKNALGNNGGAPKGNQNAVTHGFFSKFLPEETLSIMEGI QERSPVDMIWDQIQIQYAAIIRAQKIMFVSDKQEMIKELKKKKSVLSETNEVEEEEFE FQFSWDRHATFLNAQSRAMAELRNLIKQFDELAHSEDERRLKLEHMRLNINKKKIEIE ELTEEDKPFEITIVNKGDDSD*" gene complement(2555192..2555911) /gene="yqaS" /locus_tag="BSU_26200" /old_locus_tag="BSU26200" CDS complement(2555979..2556443) /gene="yqaR" /locus_tag="BSU_26210" /old_locus_tag="BSU26210" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein; skin element" /protein_id="NP_390498.1" /db_xref="EnsemblGenomes-Gn:BSU26210" /db_xref="EnsemblGenomes-Tr:CAB14562" /db_xref="SubtiList:BG11269" /db_xref="UniProtKB/Swiss-Prot:P45914" /translation="MIQIDFGTVITSAITAVFFTGGTNYVLQKKNRKGNEIFTKGYIL IDEIYNINNKRIETAAAFVPFYNHPEGYLEKLHTDYFKELSAFELIVKKFSILFDKEL NIKLQEYINYLREVEVALRGFMNDDPIIEVNFNQEYIERLIDEITNLIKKHI*" gene complement(2555979..2556443) /gene="yqaR" /locus_tag="BSU_26210" /old_locus_tag="BSU26210" downshifts complement(2556015) /Source="Nicolas_upshifts" /id="D1352" /incds=0 /nref=3 /ntot=110 /MaxReadThrough="4.51141" /MaxDrop="2.49083" /score="14.4586367" /energy="-6.1" /TU="U2027" /idTUdmin="U2030" /TUdmin=1144 /isTUend="FALSE" promotor_-10 complement(2556455..2556473) /Source="Nicolas_upshift_promotors" /id="U2027" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2837 /SigmaFactorBS="taggttttatacaacagtttcgttcgacaaattttgcgaata GTACCTGTatcgctctcttttGCCGATAATTAGTAAAAGGaggggatgaaattgattc a" /listShort="yqaR, yqaS, yqaT" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2556476) /Source="Nicolas_upshifts" /id="U2027" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2837 /SigmaFactorBS="taggttttatacaacagtttcgttcgacaaattttgcgaata GTACCTGTatcgctctcttttGCCGATAATTAGTAAAAGGaggggatgaaattgattc a" /listShort="yqaR, yqaS, yqaT" /GFF_Attribute="listLong" promotor_-35 complement(2556487..2556494) /Source="Nicolas_upshift_promotors" /id="U2027" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2837 /SigmaFactorBS="taggttttatacaacagtttcgttcgacaaattttgcgaata GTACCTGTatcgctctcttttGCCGATAATTAGTAAAAGGaggggatgaaattgattc a" /listShort="yqaR, yqaS, yqaT" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(2556575..2556594) /Source="Nicolas_upshift_promotors" /id="U2028" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.451548451548452" /psig="0.999000999001" /xcortree=1842 /SigmaFactorBS="ccaattatgccaagattgccactttgagcgttTGTTGaatct gaaaaaatctgTAGTGTAAAATGGGAGGCAGgtcggcgcggcgaattattcctgcgtc a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2556587) /Source="Nicolas_upshifts" /id="U2028" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.451548451548452" /psig="0.999000999001" /xcortree=1842 /SigmaFactorBS="ccaattatgccaagattgccactttgagcgttTGTTGaatct gaaaaaatctgTAGTGTAAAATGGGAGGCAGgtcggcgcggcgaattattcctgcgtc a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" CDS complement(2556587..2557042) /gene="yqaQ" /locus_tag="BSU_26220" /old_locus_tag="BSU26220" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type f: factor" /codon_start=1 /transl_table=11 /product="putative phage DNA-binding protein; skin element" /protein_id="NP_390499.1" /db_xref="EnsemblGenomes-Gn:BSU26220" /db_xref="EnsemblGenomes-Tr:CAB14563" /db_xref="GOA:P45948" /db_xref="InterPro:IPR013324" /db_xref="SubtiList:BG11268" /db_xref="UniProtKB/Swiss-Prot:P45948" /translation="MNRKEIENLINSYHWMVKEVRRLQRVLYGSVIPMKNWGVAQYGL EATMPKGSPGKSQAELRQMDMREERLFKRLKYYEERVYAVELGAEKIHGEQHKVIYDC MMEGMSYRAISLHLGISRETVRKMKDEFISQLCQDCHFERLLNLKKSVV*" gene complement(2556587..2557042) /gene="yqaQ" /locus_tag="BSU_26220" /old_locus_tag="BSU26220" promotor_-35 complement(2556611..2556615) /Source="Nicolas_upshift_promotors" /id="U2028" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.451548451548452" /psig="0.999000999001" /xcortree=1842 /SigmaFactorBS="ccaattatgccaagattgccactttgagcgttTGTTGaatct gaaaaaatctgTAGTGTAAAATGGGAGGCAGgtcggcgcggcgaattattcctgcgtc a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" S_feature complement(2557095..2558242) /Source="Nicolas_S_feature" /locus_tag="new_2691497_2692644_c" /HighExp="S6, S7, S8, C30, Lbstat, HiOs, Gly, BC, BT, M9-stat" /AntisenseName="yqaP" /AntisenseCor="-0.46437062782716898" /AntisenseRegPval="-15.1" /CDS_PredictionProba="NA" /TUshortSig="SigK" /TUshortPSig="0.998" /TUlongSig="NA" /TUlongPSig="NA" /label="S980" downshifts complement(2557137) /Source="Nicolas_upshifts" /id="D1353" /incds=0 /nref=4 /ntot=109 /MaxReadThrough="1.36767" /MaxDrop="4.23865" /score="20.7400212" /energy="-22.6" /TU="NA" /idTUdmin="U2030" /TUdmin=22 /isTUend="TRUE" promotor_-35 2557183..2557190 /Source="Nicolas_upshift_promotors" /id="U2029" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.91008991008991" /psig=1 /xcortree=3203 /SigmaFactorBS="tggactaactggatattttatgctttaatgaattcacattac ctaaggaaaaaaaTTCAACTCcctccttaaaTATGGTAAAATTTTATTATAaagtagt g" /listShort="yqaP, S981" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 2557188 /Source="Nicolas_upshifts" /id="U2029" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.91008991008991" /psig=1 /xcortree=3203 /SigmaFactorBS="tggactaactggatattttatgctttaatgaattcacattac ctaaggaaaaaaaTTCAACTCcctccttaaaTATGGTAAAATTTTATTATAaagtagt g" /listShort="yqaP, S981" /GFF_Attribute="listLong" promotor_-10 2557201..2557220 /Source="Nicolas_upshift_promotors" /id="U2029" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.91008991008991" /psig=1 /xcortree=3203 /SigmaFactorBS="tggactaactggatattttatgctttaatgaattcacattac ctaaggaaaaaaaTTCAACTCcctccttaaaTATGGTAAAATTTTATTATAaagtagt g" /listShort="yqaP, S981" /GFF_Attribute="listLong" /label="promotor_-10" CDS 2557240..2558169 /gene="yqaP" /locus_tag="BSU_26230" /old_locus_tag="BSU26230" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved phage protein of unknown function; skin element" /protein_id="NP_390500.1" /db_xref="EnsemblGenomes-Gn:BSU26230" /db_xref="EnsemblGenomes-Tr:CAB14564" /db_xref="SubtiList:BG11267" /db_xref="UniProtKB/Swiss-Prot:P45913" /translation="MRVREIKNLLDNYNKQIGVSVSHVPHSNRKTVLNLQKSLDAINE LSKLGFLDDDIERFKDLGSIYYSRVPEDKIEVDNHIANQITNHIKIVKEKLRGFGILI DQSVSDQNENVISVKLPQYNSLEELEKFIKKLNNAFQNGITLEEINGHYKLQGFDTGS MWIDILVNSSAAVIFVGQLIDAAINISKRSQELLITKANIEKLALQNEQLKLQVETSK ALLDGIEKGIDTITDAEIKNVTEGANYSTESIGHIKQSVKIFAELLHEGTQFHPSLDA PSETVEAFPEPQKNLEEPQQLLETLADNLPEQE*" gene 2557240..2558169 /gene="yqaP" /locus_tag="BSU_26230" /old_locus_tag="BSU26230" downshifts 2558161 /Source="Nicolas_upshifts" /id="D1354" /incds=0 /nref=27 /ntot=172 /MaxReadThrough="5.25742" /MaxDrop="3.87932" /score="-5.04773631" /energy="-8.8" /TU="U2029" /idTUdmin="U2029" /TUdmin="-462" /isTUend="FALSE" S_feature 2558206..2558511 /Source="Nicolas_S_feature" /locus_tag="new_2692608_2692913" /HighExp="M9-stat, LoTm, T3.30H, T4.0H, T0.30H, Lbstat, T5.0H, T2.0H, T3.0H, T2.30H" /AntisenseName="yqaO" /AntisenseCor="-0.289049566701301" /AntisenseRegPval="-5.8" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S981" CDS complement(2558243..2558449) /gene="yqaO" /locus_tag="BSU_26240" /old_locus_tag="BSU26240" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved phage protein of unknown function; skin element" /protein_id="NP_390501.1" /db_xref="EnsemblGenomes-Gn:BSU26240" /db_xref="EnsemblGenomes-Tr:CAB14565" /db_xref="InterPro:IPR035530" /db_xref="SubtiList:BG11266" /db_xref="UniProtKB/Swiss-Prot:P45912" /translation="MYNPREINIKKDFTIQQKIDPGKVQIIVLDGNQGTAHVLDAPEH GKTVIQTVKGSFARVDHEIGFKVK*" gene complement(2558243..2558449) /gene="yqaO" /locus_tag="BSU_26240" /old_locus_tag="BSU26240" S_feature complement(2558450..2558530) /Source="Nicolas_S_feature" /locus_tag="new_2692852_2692932_c" /HighExp="S6, S8, S7, S5, BT, C30, Pyr, B36, G/S, Glucon" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigK" /TUshortPSig="0.998" /TUlongSig="NA" /TUlongPSig="NA" /label="S982" downshifts 2558468 /Source="Nicolas_upshifts" /id="D1355" /incds=0 /nref=84 /ntot=200 /MaxReadThrough="2.89711" /MaxDrop="5.40073" /score="28.5080646" /energy="-11.3" /TU="U2029" /idTUdmin="U2029" /TUdmin="-155" /isTUend="FALSE" CDS complement(2558531..2558959) /gene="yqaN" /locus_tag="BSU_26250" /old_locus_tag="BSU26250" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 20889742; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative Holliday junction resolvase; skin element" /protein_id="NP_390502.1" /db_xref="EnsemblGenomes-Gn:BSU26250" /db_xref="EnsemblGenomes-Tr:CAB14566" /db_xref="GOA:P45911" /db_xref="InterPro:IPR008822" /db_xref="InterPro:IPR036614" /db_xref="SubtiList:BG11265" /db_xref="UniProtKB/Swiss-Prot:P45911" /translation="MDCIKFTVYGEPVAQGRPRGSIRNGKVHMRDPAKSKYFKQYVAL VASQHRPETIITGPVSMDVKVYRPMPKSVSNSKKKKEKAEKGLLRPTTKPDVDNYVKG VKDALNHLIYKDDSQVVDLKVSKFYSEEPRVEVMIREVSA*" gene complement(2558531..2558959) /gene="yqaN" /locus_tag="BSU_26250" /old_locus_tag="BSU26250" CDS complement(2559055..2559204) /gene="yqzO" /locus_tag="BSU_26259" /old_locus_tag="BSU26259" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function; PubMedId : 20889742" /codon_start=1 /transl_table=11 /product="hypothetical protein; skin element" /protein_id="YP_003097764.1" /db_xref="EnsemblGenomes-Gn:BSU26259" /db_xref="EnsemblGenomes-Tr:CAX52665" /db_xref="UniProtKB/Swiss-Prot:C0H455" /translation="MGMKKKTNIKATGGLYIFGPSNRNEGKDLTPTIRLLEEKIKQME RMLSA*" gene complement(2559055..2559204) /gene="yqzO" /locus_tag="BSU_26259" /old_locus_tag="BSU26259" CDS complement(2559195..2560136) /gene="sknM" /locus_tag="BSU_26260" /old_locus_tag="BSU26260" /experiment="publication(s) with functional evidences, PMID:20889742" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 20889742; Product type h: extrachromosomal origin" /codon_start=1 /transl_table=11 /product="putative helicase loader; skin element" /protein_id="NP_390503.3" /db_xref="EnsemblGenomes-Gn:BSU26260" /db_xref="EnsemblGenomes-Tr:CAB14567" /db_xref="GOA:P45910" /db_xref="InterPro:IPR002611" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG11264" /db_xref="UniProtKB/Swiss-Prot:P45910" /translation="MAINKAVSIDTAFQTIMQELRERSARFLGTKQAVSEEKAEFDCP YCKDRGIVVYRVHKDTSWHLDEQLDLMVPDDMVSEDDFLLGKVCTPDKASEWKDTYSK QCECVRRKKIARLMAASGITEEFEKLLFGNFITDGKPDMIKDAYECAVEYYKDFQKIK GERQNSIALLGQPGSGKTHLLTAIMNNLIKKKSVHCMYFPYVEGMGDLKANFDNLEAK LDAMRKVEVLFIDDLFKPINGQPRATDWQVEQIQSVLNYRYLNHKPLLISSELTIDEI LDIDEALGSRIHQMCRDYIVIIRGDRMQLNHRLGDWE*" gene complement(2559195..2560136) /gene="sknM" /locus_tag="BSU_26260" /old_locus_tag="BSU26260" promotor_-10 complement(2559238..2559257) /Source="Nicolas_upshift_promotors" /id="U2030" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=1373 /SigmaFactorBS="gagattttggatatagacgaggctcttggttcacGAATTCAC CAgatgtgccgtgatTACATAGTGATTATTAGAGGcgatcgaatgcaattaaatcata g" /listShort="yqzO, yqaN, S982, yqaO, S980" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2559254) /Source="Nicolas_upshifts" /id="U2030" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=1373 /SigmaFactorBS="gagattttggatatagacgaggctcttggttcacGAATTCAC CAgatgtgccgtgatTACATAGTGATTATTAGAGGcgatcgaatgcaattaaatcata g" /listShort="yqzO, yqaN, S982, yqaO, S980" /GFF_Attribute="listLong" promotor_-35 complement(2559271..2559280) /Source="Nicolas_upshift_promotors" /id="U2030" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=1373 /SigmaFactorBS="gagattttggatatagacgaggctcttggttcacGAATTCAC CAgatgtgccgtgatTACATAGTGATTATTAGAGGcgatcgaatgcaattaaatcata g" /listShort="yqzO, yqaN, S982, yqaO, S980" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2560018..2560695) /gene="yqaL" /locus_tag="BSU_26270" /old_locus_tag="BSU26270" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 20889742; Product type f: factor" /codon_start=1 /transl_table=11 /product="putative DNA-binding protein; skin element" /protein_id="NP_390504.2" /db_xref="EnsemblGenomes-Gn:BSU26270" /db_xref="EnsemblGenomes-Tr:CAB14568" /db_xref="InterPro:IPR006343" /db_xref="InterPro:IPR034829" /db_xref="InterPro:IPR036388" /db_xref="SubtiList:BG11263" /db_xref="UniProtKB/Swiss-Prot:P45909" /translation="MVIPRLPFKEFRDEKIYDHLFKRAEYRPNQELELGQTIIKVVEL AKDFNWSAAQIKYSLDRMEKQGYIKLHRLPQKRGLIVTILHYADYIQLGNYMKNKALE PAQIEHQEVDDKMKNAFELYENKVARSVGPMEAQRIGYMVDDYGEEKVMEAIKTAFQL KGKAASLSYVQAILSNPFTQKRKEKQYGYKQSSQYRHRISNDHAGTSGKVSPLFGNKT GRIRRKG*" gene complement(2560018..2560695) /gene="yqaL" /locus_tag="BSU_26270" /old_locus_tag="BSU26270" CDS complement(2560771..2561625) /gene="yqaK" /locus_tag="BSU_26280" /old_locus_tag="BSU26280" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 20889742; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative DNA recombination protein; skin element" /protein_id="NP_390505.1" /db_xref="EnsemblGenomes-Gn:BSU26280" /db_xref="EnsemblGenomes-Tr:CAB14569" /db_xref="GOA:P45908" /db_xref="InterPro:IPR004590" /db_xref="InterPro:IPR018330" /db_xref="SubtiList:BG11262" /db_xref="UniProtKB/Swiss-Prot:P45908" /translation="MATNQSIKNNIQKKQKNVPVQQQGATMKGLLSSPSVIKRFEEVL GKRATQFTASILSLYNSEQMLQKTDPMSVISSAMVAATLDLPIDKNLGYAWIVPYGGK AQFQLGYKGYIQLALRTGQYKSINCIPIHEGELQKWNPLTEEIEIDFEKRESDAVIGY AAYFELINGFRKTVYWTKAQVEKHKKKFSKSDFGWKNDWDAMALKTVLKAVLSKWGIL SVEMQKAVIEEDETRERIDITNEADSSEIIDSEPSNKDETEKPSAQETDPFDGKPVDI KDDELPFD*" gene complement(2560771..2561625) /gene="yqaK" /locus_tag="BSU_26280" /old_locus_tag="BSU26280" CDS complement(2561628..2562587) /gene="yqaJ" /locus_tag="BSU_26290" /old_locus_tag="BSU26290" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 20889742; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative nuclease; skin element" /protein_id="NP_390506.1" /db_xref="EnsemblGenomes-Gn:BSU26290" /db_xref="EnsemblGenomes-Tr:CAB14570" /db_xref="GOA:P45907" /db_xref="InterPro:IPR011335" /db_xref="InterPro:IPR011604" /db_xref="InterPro:IPR017482" /db_xref="InterPro:IPR019080" /db_xref="SubtiList:BG11261" /db_xref="UniProtKB/Swiss-Prot:P45907" /translation="MTSKRAEVLAKNSEMSRDEWLIERRKGIGGSDASIILGLNKWKT PFELWLDKTGQVPVSESQSEAAYFGSLLEDIVAKEFEIRSGKKVRRKKAILRHPEYNF ILANVDRMIVGEKAILECKTTSAYNLKEWEDEEIPESYIVQVQHYLGVLGPEYRKAYF AVLIGGNKFVWKEIERDDELIDMIFKAEIEFWNDKVLGGQAPALDGSSAAEEYLKKRY AETENNKAIDLTAANRERIQQYLLIKEQISELQSQAKELENQIKHEMKDAEYGFIGNY QACWKPVVSNRIDTKKLKDQFPDVYEKVKKETHFRRFGIKEVS*" gene complement(2561628..2562587) /gene="yqaJ" /locus_tag="BSU_26290" /old_locus_tag="BSU26290" CDS complement(2562693..2562887) /gene="yqaI" /locus_tag="BSU_26300" /old_locus_tag="BSU26300" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function; PubMedId : 20889742" /codon_start=1 /transl_table=11 /product="hypothetical protein; skin element" /protein_id="NP_390507.1" /db_xref="EnsemblGenomes-Gn:BSU26300" /db_xref="EnsemblGenomes-Tr:CAB14571" /db_xref="InterPro:IPR018474" /db_xref="InterPro:IPR023118" /db_xref="PDB:2DSM" /db_xref="SubtiList:BG11260" /db_xref="UniProtKB/Swiss-Prot:P45906" /translation="MVENPMVINNWHDKLTETDVQIDFYGDEVTPVDDYVIDGGEIIL RENLERYLREQLGFEFKNAQ*" gene complement(2562693..2562887) /gene="yqaI" /locus_tag="BSU_26300" /old_locus_tag="BSU26300" CDS complement(2562847..2563020) /locus_tag="BSU_26305" /old_locus_tag="BSU26305" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein; skin element" /protein_id="YP_009513981.1" /translation="MMVHFVHKPATALEVRKWCVMIRNNSEFHLLWDRRADKFREENK NGRKSNGHKQLAR*" gene complement(2562847..2563020) /locus_tag="BSU_26305" /old_locus_tag="BSU26305" CDS complement(2563017..2563274) /gene="sknH" /locus_tag="BSU_26310" /old_locus_tag="BSU26310" /experiment="publication(s) with functional evidences, PMID:20889742" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 20889742; Product type f: factor" /codon_start=1 /transl_table=11 /product="skin element; factor binding to DnaA" /protein_id="NP_390508.1" /db_xref="EnsemblGenomes-Gn:BSU26310" /db_xref="EnsemblGenomes-Tr:CAB14572" /db_xref="InterPro:IPR020278" /db_xref="SubtiList:BG11259" /db_xref="UniProtKB/Swiss-Prot:P45905" /translation="MNTNHFLKADVPIAKRKIESAEELSIMLSEALRDGDYEEAISLA GSIKVLTEDISRLANKGRLYETALKMQQQGINLTVVSRCIG*" gene complement(2563017..2563274) /gene="sknH" /locus_tag="BSU_26310" /old_locus_tag="BSU26310" CDS complement(2563271..2563840) /gene="yqaG" /locus_tag="BSU_26320" /old_locus_tag="BSU26320" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative transcriptional regulator; skin element" /protein_id="NP_390509.1" /db_xref="EnsemblGenomes-Gn:BSU26320" /db_xref="EnsemblGenomes-Tr:CAB14573" /db_xref="GOA:P45904" /db_xref="InterPro:IPR001387" /db_xref="InterPro:IPR010982" /db_xref="SubtiList:BG11258" /db_xref="UniProtKB/Swiss-Prot:P45904" /translation="MENNPYNMRNLPQIMRSARKAAGLSQYQIGKLIGGKDQRYVSDV ENGLAKLTPELCIKWFEKCAAYEHIDLVHYLFKLHPTAAAPIDPALNECASNAVINMV HQLEEALQATKHLARWLTDNRPGKTEELPMADIKQIFDLIAANKTLIYSLVRTHGLKM QELADRWTRKALVDQVAMAKQEGRQAVSV*" gene complement(2563271..2563840) /gene="yqaG" /locus_tag="BSU_26320" /old_locus_tag="BSU26320" CDS complement(2563914..2564054) /gene="yqdA" /locus_tag="BSU_26330" /old_locus_tag="BSU26330" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function; PubMedId : 20889742" /codon_start=1 /transl_table=11 /product="hypothetical protein; skin element" /protein_id="NP_390510.1" /db_xref="EnsemblGenomes-Gn:BSU26330" /db_xref="EnsemblGenomes-Tr:CAB14574" /db_xref="SubtiList:BG11508" /db_xref="UniProtKB/Swiss-Prot:P54372" /translation="MKVILKKGPLFEQAEAKAYKYLSGILVQRMNEHQEKLAQKNKKE SA*" gene complement(2563914..2564054) /gene="yqdA" /locus_tag="BSU_26330" /old_locus_tag="BSU26330" CDS complement(2564084..2564314) /gene="yqaF" /locus_tag="BSU_26340" /old_locus_tag="BSU26340" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 20889742; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative transcriptional regulator; skin element" /protein_id="NP_390511.1" /db_xref="EnsemblGenomes-Gn:BSU26340" /db_xref="EnsemblGenomes-Tr:CAB14575" /db_xref="GOA:P45903" /db_xref="InterPro:IPR001387" /db_xref="InterPro:IPR010982" /db_xref="SubtiList:BG11257" /db_xref="UniProtKB/Swiss-Prot:P45903" /translation="MMRKWLKKNRLEKGFTQEEVAKAAQIGRAYYTMIENGTRKPSVI VSKKIGEKLGFDWTIFFEDVCNETKHNSKDSA*" gene complement(2564084..2564314) /gene="yqaF" /locus_tag="BSU_26340" /old_locus_tag="BSU26340" promotor_-35 2564425..2564428 /Source="Nicolas_upshift_promotors" /id="U2031" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.632367632367632" /psig="0.999000999001" /xcortree=3225 /SigmaFactorBS="ttcataaaaaaagtatcgttttgttaccaaaaCTTAtatgta accctttgTTACGTTACAATGAGATATAgaataaaaacaaaagtcaggtgattaatat g" /listShort="yqaE, S983" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2564443..2564462 /Source="Nicolas_upshift_promotors" /id="U2031" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.632367632367632" /psig="0.999000999001" /xcortree=3225 /SigmaFactorBS="ttcataaaaaaagtatcgttttgttaccaaaaCTTAtatgta accctttgTTACGTTACAATGAGATATAgaataaaaacaaaagtcaggtgattaatat g" /listShort="yqaE, S983" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2564453 /Source="Nicolas_upshifts" /id="U2031" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.632367632367632" /psig="0.999000999001" /xcortree=3225 /SigmaFactorBS="ttcataaaaaaagtatcgttttgttaccaaaaCTTAtatgta accctttgTTACGTTACAATGAGATATAgaataaaaacaaaagtcaggtgattaatat g" /listShort="yqaE, S983" /GFF_Attribute="listLong" CDS 2564491..2564841 /gene="sknR" /locus_tag="BSU_26350" /old_locus_tag="BSU26350" /function="16.3: Control" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:20889742" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 20889742; Product type r: regulator" /codon_start=1 /transl_table=11 /product="skin element; transcriptional repressor of yqaF-yqaN operon (Xre family)" /protein_id="NP_390512.1" /db_xref="EnsemblGenomes-Gn:BSU26350" /db_xref="EnsemblGenomes-Tr:CAB14576" /db_xref="GOA:P45902" /db_xref="InterPro:IPR001387" /db_xref="InterPro:IPR010982" /db_xref="SubtiList:BG11256" /db_xref="UniProtKB/Swiss-Prot:P45902" /translation="MFSENLKKCRKQKKLTQQNMADKLGITRPAYTAYELGSREPDYK TLINISNILDVSLDYLLKGESNEKVFQDEAKKVLNDPETFLAAKDGEVTDEILQAALE IITEQLKERRKSDK*" gene 2564491..2564841 /gene="sknR" /locus_tag="BSU_26350" /old_locus_tag="BSU26350" S_feature 2564842..2564980 /Source="Nicolas_S_feature" /locus_tag="new_2699244_2699382" /HighExp="Cold, Lbtran, S8, LPhT, M9-stat, HiOs, Gly, HiTm, LBGstat, LoTm" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S983" downshifts 2564937 /Source="Nicolas_upshifts" /id="D1356" /incds=0 /nref=16 /ntot=206 /MaxReadThrough="2.91165" /MaxDrop="4.79693" /score="-0.848064104" /energy="-4.5" /TU="U2031" /idTUdmin="U2031" /TUdmin="-88" /isTUend="FALSE" CDS complement(2565108..2565275) /gene="yqaD" /locus_tag="BSU_26360" /old_locus_tag="BSU26360" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved phage protein of unknown function; skin element" /protein_id="NP_390513.1" /db_xref="EnsemblGenomes-Gn:BSU26360" /db_xref="EnsemblGenomes-Tr:CAB14577" /db_xref="GOA:P45901" /db_xref="SubtiList:BG11255" /db_xref="UniProtKB/Swiss-Prot:P45901" /translation="MKNNDKKKEVQRKYREEIKKKKQKNEDNKNFIKETIIVVTIIVL FIFFTYTLQGF*" gene complement(2565108..2565275) /gene="yqaD" /locus_tag="BSU_26360" /old_locus_tag="BSU26360" CDS complement(2565631..2566167) /gene="yqaC" /locus_tag="BSU_26370" /old_locus_tag="BSU26370" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative kinase / phosphatase; skin element" /protein_id="NP_390514.1" /db_xref="EnsemblGenomes-Gn:BSU26370" /db_xref="EnsemblGenomes-Tr:CAB14578" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG11254" /db_xref="UniProtKB/Swiss-Prot:P45900" /translation="MKKNIHILGASGVGTSTLGAALSKRLPHTHLDTDNYYWLDKFTK KREIPERRKLLEKDLTINEKWILSGAVCGWGDNLKSYFDLVVFLWIPQDIRLERLRHR EFQRYGNEVLAGGSKYEQSKTFLEWASLYDNAGMEVRSRALHEHWMADLSCPVLKIED DCSVNERVDRVLDYLSSN*" gene complement(2565631..2566167) /gene="yqaC" /locus_tag="BSU_26370" /old_locus_tag="BSU26370" promotor_-10 complement(2566217..2566235) /Source="Nicolas_upshift_promotors" /id="U2032" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.992007992007992" /psig="0.992007992007992" /xcortree=542 /SigmaFactorBS="acacgcatctggatttccctcgaaaagtAAAGGTCTTttagg gatttaTGTCAAAATAATAGTAAGTacgttatgcaacaaacagggagtttggttgctt a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2566223) /Source="Nicolas_upshifts" /id="U2032" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.992007992007992" /psig="0.992007992007992" /xcortree=542 /SigmaFactorBS="acacgcatctggatttccctcgaaaagtAAAGGTCTTttagg gatttaTGTCAAAATAATAGTAAGTacgttatgcaacaaacagggagtttggttgctt a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(2566247..2566255) /Source="Nicolas_upshift_promotors" /id="U2032" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.992007992007992" /psig="0.992007992007992" /xcortree=542 /SigmaFactorBS="acacgcatctggatttccctcgaaaagtAAAGGTCTTttagg gatttaTGTCAAAATAATAGTAAGTacgttatgcaacaaacagggagtttggttgctt a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 2566259..2566263 /Source="Nicolas_upshift_promotors" /id="U2033" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.519480519480519" /psig="0.999000999001" /xcortree=1908 /SigmaFactorBS="ttactattattttgacataaatccctaaaagacctttactTT TCGagggaaatccagatgCGTGTTAAAATCATAATACTtacgaaaacagtcatgatta a" /listShort="yqaB, spoIIIC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2566279..2566298 /Source="Nicolas_upshift_promotors" /id="U2033" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.519480519480519" /psig="0.999000999001" /xcortree=1908 /SigmaFactorBS="ttactattattttgacataaatccctaaaagacctttactTT TCGagggaaatccagatgCGTGTTAAAATCATAATACTtacgaaaacagtcatgatta a" /listShort="yqaB, spoIIIC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2566279 /Source="Nicolas_upshifts" /id="U2033" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.519480519480519" /psig="0.999000999001" /xcortree=1908 /SigmaFactorBS="ttactattattttgacataaatccctaaaagacctttactTT TCGagggaaatccagatgCGTGTTAAAATCATAATACTtacgaaaacagtcatgatta a" /listShort="yqaB, spoIIIC" /GFF_Attribute="listLong" CDS 2566436..2566954 /gene="yqaB" /locus_tag="BSU_26380" /old_locus_tag="BSU26380" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative peptidase; skin element" /protein_id="NP_390515.1" /db_xref="EnsemblGenomes-Gn:BSU26380" /db_xref="EnsemblGenomes-Tr:CAB14579" /db_xref="InterPro:IPR010359" /db_xref="SubtiList:BG11253" /db_xref="UniProtKB/Swiss-Prot:P45899" /translation="MRYTNSHLEDWIENLYKKIDITEPEQINFERIAEALDIRLSFKP VTSFALKHSGIYNICLDSRKSRTEQWYDFAHEFCHIYRHEGDKKTMPATWTDYLDWQS NYFTYHFCIPTCMLRNINLPYIQSHAIENVAWLFKVSPSFAKKRLSIYYRKLTQHLFS QTVTGNLCPPFL*" gene 2566436..2566954 /gene="yqaB" /locus_tag="BSU_26380" /old_locus_tag="BSU26380" misc_feature complement(2566921..2566939) /Source="Nicolas_upshift_promotors" /id="U2034" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.888111888111888" /psig="0.888111888111888" /xcortree=1184 /SigmaFactorBS="acgtctttttttgtttttttcaatgcgcgcaaatgcatgagg atttcattattcattacaaaaaggggggGCATAAATTTCCCGTAACAgtttgactaaa t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" CDS 2566936..2567352 /gene="sigKc" /locus_tag="BSU_26390" /old_locus_tag="BSU26390" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:2163341, 7704261, 8969508" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 2163341, 7704261, 8969508; Product type f: factor" /pseudo /codon_start=1 /transl_table=11 /product="RNA polymerase sporulation-specific sigma-K factor precursor (Sigma-27) (C-terminal fragment)" /db_xref="GOA:P12254" /db_xref="InterPro:IPR000943" /db_xref="InterPro:IPR007627" /db_xref="InterPro:IPR007630" /db_xref="InterPro:IPR013324" /db_xref="InterPro:IPR013325" /db_xref="InterPro:IPR014284" /db_xref="PSEUDO:CAB14580.1" /db_xref="SubtiList:BG10919" /db_xref="UniProtKB/Swiss-Prot:P12254" /translation="MPPLFVMNNEILMHLRALKKTKKDVSLHDPIGQDKEGNEISLID VLKSENEDVIDTIQLNMELEKVKQYIDILDDREKEVIVGRFGLDLKKEKTQREIAKEL GISRSYVSRIEKRALMKMFHEFYRAEKEKRKKAKGK*" gene 2566936..2567352 /gene="sigKc" /locus_tag="BSU_26390" /old_locus_tag="BSU26390" /pseudo misc_feature 2566941..2566955 /Source="Nicolas_upshift_promotors" /id="U2035" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.647352647352647" /psig="0.217782217782218" /xcortree=1060 /SigmaFactorBS="tcaacatttatttagtcaaactgttacgggaaatttatgccC CCCCTTTTTGTAATgaataatgaaatcctcatgcatttgcgcgcattgaaaaaaacaa a" /listShort="spoIIIC, S984" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(2566949) /Source="Nicolas_upshifts" /id="U2034" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.888111888111888" /psig="0.888111888111888" /xcortree=1184 /SigmaFactorBS="acgtctttttttgtttttttcaatgcgcgcaaatgcatgagg atttcattattcattacaaaaaggggggGCATAAATTTCCCGTAACAgtttgactaaa t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" upshifts 2566960 /Source="Nicolas_upshifts" /id="U2035" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.647352647352647" /psig="0.217782217782218" /xcortree=1060 /SigmaFactorBS="tcaacatttatttagtcaaactgttacgggaaatttatgccC CCCCTTTTTGTAATgaataatgaaatcctcatgcatttgcgcgcattgaaaaaaacaa a" /listShort="spoIIIC, S984" /GFF_Attribute="listLong" downshifts 2567336 /Source="Nicolas_upshifts" /id="D1357" /incds=0 /nref=50 /ntot=108 /MaxReadThrough="3.60274" /MaxDrop="5.60264" /score="-0.848064104" /energy="-4.5" /TU="U2035" /idTUdmin="U2033" /TUdmin=1 /isTUend="TRUE" CDS 2567352..2567468 /locus_tag="BSU_26399" /old_locus_tag="BSU26399" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_009513982.1" /translation="MQKKPDLILRLSLFERVMKIIFFIADKLSEKDRQDRNK*" gene 2567352..2567468 /locus_tag="BSU_26399" /old_locus_tag="BSU26399" S_feature 2567381..2568715 /Source="Nicolas_S_feature" /locus_tag="new_2701783_2703117" /HighExp="S8, S6, S7, S5, S4, BT, B36, dia15, C30, H2O2" /AntisenseName="psiE" /AntisenseCor="0.376363934894826" /AntisenseRegPval="-9.8000000000000007" /CDS_PredictionProba="0.117191" /TUshortSig="Sig-" /TUshortPSig="0.218" /TUlongSig="NA" /TUlongPSig="NA" /label="S984" downshifts complement(2567499) /Source="Nicolas_upshifts" /id="D1358" /incds=0 /nref=1 /ntot=20 /MaxReadThrough="3.25265" /MaxDrop="3.18978" /score="3.17084908" /energy="-14.7" /TU="NA" /idTUdmin="U2036" /TUdmin=66 /isTUend="FALSE" CDS complement(2567577..2567741) /gene="yrkS" /locus_tag="BSU_26400" /old_locus_tag="BSU26400" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="NP_390517.1" /db_xref="EnsemblGenomes-Gn:BSU26400" /db_xref="EnsemblGenomes-Tr:CAB14581" /db_xref="SubtiList:BG11785" /db_xref="UniProtKB/Swiss-Prot:P54446" /translation="MKVIIIEGLQTDKCMNDCYHYLIKLYRQEIQGDSNISWNKRSRD RASTARSRPV*" gene complement(2567577..2567741) /gene="yrkS" /locus_tag="BSU_26400" /old_locus_tag="BSU26400" promotor_-10 complement(2567671..2567690) /Source="Nicolas_upshift_promotors" /id="U2036" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.824175824175824" /psig="0.975024975024975" /xcortree=1403 /SigmaFactorBS="aggggtgatgtattttatgaaggtaataatcatcgagggact gcaAACTGACAaatgcatgaacgatTGCTATCATTATTTAATAAAactttataggcag g" /listShort="yrkS" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2567697) /Source="Nicolas_upshifts" /id="U2036" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.824175824175824" /psig="0.975024975024975" /xcortree=1403 /SigmaFactorBS="aggggtgatgtattttatgaaggtaataatcatcgagggact gcaAACTGACAaatgcatgaacgatTGCTATCATTATTTAATAAAactttataggcag g" /listShort="yrkS" /GFF_Attribute="listLong" promotor_-35 complement(2567705..2567712) /Source="Nicolas_upshift_promotors" /id="U2036" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.824175824175824" /psig="0.975024975024975" /xcortree=1403 /SigmaFactorBS="aggggtgatgtattttatgaaggtaataatcatcgagggact gcaAACTGACAaatgcatgaacgatTGCTATCATTATTTAATAAAactttataggcag g" /listShort="yrkS" /GFF_Attribute="listLong" /label="promotor_-35" downshifts complement(2567875) /Source="Nicolas_upshifts" /id="D1359" /incds=0 /nref=79 /ntot=219 /MaxReadThrough="1.20909" /MaxDrop="4.40328" /score="39.3560776" /energy="-10.6" /TU="NA" /idTUdmin="U2036" /TUdmin="-310" /isTUend="FALSE" CDS complement(2568286..2568702) /gene="psiE" /locus_tag="BSU_26410" /old_locus_tag="BSU26410" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 12897016, 15849754, 16850406; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="phosphate starvation inducible protein" /protein_id="NP_390518.2" /db_xref="EnsemblGenomes-Gn:BSU26410" /db_xref="EnsemblGenomes-Tr:CAB14582" /db_xref="GOA:P54445" /db_xref="InterPro:IPR009315" /db_xref="InterPro:IPR020948" /db_xref="SubtiList:BG11784" /db_xref="UniProtKB/Swiss-Prot:P54445" /translation="MRFSNKFKKVPYLLQALLNVCLFFLALALSALLISETWYIVLFV YKSLFNKVDSYYEMLGELLIFFMYFEFIALIIKYFKSDFHFPLRYFIYIGITAVIRLI IIDHDQAISTFWWAMAILAMICGFFIANRRNSVVEH*" gene complement(2568286..2568702) /gene="psiE" /locus_tag="BSU_26410" /old_locus_tag="BSU26410" CDS complement(2568748..2570046) /gene="yrkQ" /locus_tag="BSU_26420" /old_locus_tag="BSU26420" /EC_number="2.7.13.3" /function="16.3: Control" /function="16.12: Sense" /experiment="publication(s) with functional evidences, PMID:11717295" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11717295; Product type rc: receptor" /codon_start=1 /transl_table=11 /product="two-component sensor histidine kinase [YrkP]" /protein_id="NP_390519.1" /db_xref="EnsemblGenomes-Gn:BSU26420" /db_xref="EnsemblGenomes-Tr:CAB14583" /db_xref="GOA:P54444" /db_xref="InterPro:IPR003660" /db_xref="InterPro:IPR003661" /db_xref="InterPro:IPR036097" /db_xref="InterPro:IPR036890" /db_xref="SubtiList:BG11783" /db_xref="UniProtKB/Swiss-Prot:P54444" /translation="MAHLKFTLTKKLALLIMVAAIVSGVIFLTLQKITDDLIEGYLSS EEYYHEESARYIQKFSKYVSENELSTSDRKAFGEWVKKENYINLTIFKDQELQYDSIY SESDYGKEKLTQYAQNHSHPVKFSDGEGRVIIDGFYSSRYYDLAFALDLLGATLIFLI IVLFGIRQSLRYLKTIHQEIHILEGGELDYEMTIKGHDELAMIAKSIEDLRKAFLDKL KAIEELQAESRSLVTEMSHDMRTPLTSLIMNLEFAKKEGGEAGASKDRYVANAYGKAL QLKSLSDNLFAYFLLNKEYEADLETVAVKEVIYDLISDQIAILHQEHFRVHISGELPE TYINVNLEELGRVFDNVMSNLLKYADPEEKISITFVSDQEIFEIHVSNTIKLADITPE SNGLGERSIARMMSRMQGQFHSIQKNSKYYIVLRFWNTKM*" gene complement(2568748..2570046) /gene="yrkQ" /locus_tag="BSU_26420" /old_locus_tag="BSU26420" CDS complement(2570033..2570728) /gene="yrkP" /locus_tag="BSU_26430" /old_locus_tag="BSU26430" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:11717295, 18175906" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11717295, 18175906; Product type r: regulator" /codon_start=1 /transl_table=11 /product="two-component response regulator [YrkQ]" /protein_id="NP_390520.1" /db_xref="EnsemblGenomes-Gn:BSU26430" /db_xref="EnsemblGenomes-Tr:CAB14584" /db_xref="GOA:P54443" /db_xref="InterPro:IPR001789" /db_xref="InterPro:IPR001867" /db_xref="InterPro:IPR011006" /db_xref="InterPro:IPR016032" /db_xref="InterPro:IPR036388" /db_xref="SubtiList:BG11782" /db_xref="UniProtKB/Swiss-Prot:P54443" /translation="MAYRILVVEDDEDIGDLLEESLTRAGYEVLRAKDGKRALQLVND SLDLVILDIMMPGISGIETCQHIRKSSNVPILFLTARSSTLDKTEGLLAGGDDYMTKP FSEEELHARVIAQLRRYTIYQEKKEQEETFLIGGKLRVSEEFNEVWKEEKQIKLSDLE YRILKLLMNKRNKIFSAQNIYESVWGQPYFYCSNNTVMVHIRKLRSKIEDDPARPVYI KTEWGRGYRFGAS*" gene complement(2570033..2570728) /gene="yrkP" /locus_tag="BSU_26430" /old_locus_tag="BSU26430" misc_feature complement(2570794..2570811) /Source="Nicolas_upshift_promotors" /id="U2037" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.270729270729271" /psig="0.737262737262737" /xcortree=673 /SigmaFactorBS="acaaatttgtggcgagcatcagctttcataaattgttaagat ttacgtagtaTCTTATAACGTACTTATTactatgaacgatatatagtaaggacacacg a" /listShort="yrkP" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(2570803) /Source="Nicolas_upshifts" /id="U2037" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.270729270729271" /psig="0.737262737262737" /xcortree=673 /SigmaFactorBS="acaaatttgtggcgagcatcagctttcataaattgttaagat ttacgtagtaTCTTATAACGTACTTATTactatgaacgatatatagtaaggacacacg a" /listShort="yrkP" /GFF_Attribute="listLong" promotor_-35 2570889..2570895 /Source="Nicolas_upshift_promotors" /id="U2038" /multdbtbs="-" /comp="M6" /sig="Sig-" /pcomp="0.76023976023976" /psig="0.145854145854146" /xcortree=1734 /SigmaFactorBS="aatttgtcacattttctaaaaaaaatgatgacTCTTCATaaa ttgTTAAGATTCGGTCTTTATAtttatccattgtaaggctcaagtttttcagatccgc a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2570902..2570920 /Source="Nicolas_upshift_promotors" /id="U2038" /multdbtbs="-" /comp="M6" /sig="Sig-" /pcomp="0.76023976023976" /psig="0.145854145854146" /xcortree=1734 /SigmaFactorBS="aatttgtcacattttctaaaaaaaatgatgacTCTTCATaaa ttgTTAAGATTCGGTCTTTATAtttatccattgtaaggctcaagtttttcagatccgc a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2570917 /Source="Nicolas_upshifts" /id="U2038" /multdbtbs="-" /comp="M6" /sig="Sig-" /pcomp="0.76023976023976" /psig="0.145854145854146" /xcortree=1734 /SigmaFactorBS="aatttgtcacattttctaaaaaaaatgatgacTCTTCATaaa ttgTTAAGATTCGGTCTTTATAtttatccattgtaaggctcaagtttttcagatccgc a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" CDS 2570996..2572213 /gene="yrkO" /locus_tag="BSU_26440" /old_locus_tag="BSU26440" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406, 21737930; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative integral inner membrane protein" /protein_id="NP_390521.1" /db_xref="EnsemblGenomes-Gn:BSU26440" /db_xref="EnsemblGenomes-Tr:CAB14585" /db_xref="GOA:P54442" /db_xref="InterPro:IPR007349" /db_xref="SubtiList:BG11781" /db_xref="UniProtKB/Swiss-Prot:P54442" /translation="MIVQKEGRGQPVSLRERVHFLDIVRGFALLGIIIVNYFLIVDSV KGFEMASDDVLHKLVSWFAEGKFVTLFSFLFGVGFMIFMDRAAQKVESPNKLFARRLS ILLGFGILHITFVWVGDILAFYAVSGFLLLAFYKRTAKTVLRWIIALIVFQFLTPVFT MLYNVINTAGSKNPNFSEFTLFSHSSLTYMESISTRWTDMVTMAAGSFSMIYSMFLMF LLGVYFVKMEFFKDMEAKKPIWKRIWIISTIAFLITQSSILLDMFNLSENMLWKDISS VLGQNGGLTGSMFYMSTFAMLFLYLPQLRGPMMIFTKVGRMSLTCYLLHSIIGTVLFL RYGFGLADHIQSAGTFMFSLAVYFVLMSFSTLWLKRFRYGPMELVWRKLTYGKVNGSP KATPLHSEKSIQK*" gene 2570996..2572213 /gene="yrkO" /locus_tag="BSU_26440" /old_locus_tag="BSU26440" promotor_-35 2571455..2571462 /Source="Nicolas_upshift_promotors" /id="U2039" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.844155844155844" /psig="0.999000999001" /xcortree=1907 /SigmaFactorBS="tatcgcacttatcgtgtttcaaTTCCTGACtcctgttttcac aaTGTTGTACAATGTCATCAATactgcagggtcaaaaaacccgaatttttcagagttt a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2571477..2571496 /Source="Nicolas_upshift_promotors" /id="U2039" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.844155844155844" /psig="0.999000999001" /xcortree=1907 /SigmaFactorBS="tatcgcacttatcgtgtttcaaTTCCTGACtcctgttttcac aaTGTTGTACAATGTCATCAATactgcagggtcaaaaaacccgaatttttcagagttt a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2571493 /Source="Nicolas_upshifts" /id="U2039" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.844155844155844" /psig="0.999000999001" /xcortree=1907 /SigmaFactorBS="tatcgcacttatcgtgtttcaaTTCCTGACtcctgttttcac aaTGTTGTACAATGTCATCAATactgcagggtcaaaaaacccgaatttttcagagttt a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" CDS 2572132..2572380 /locus_tag="BSU_26449" /old_locus_tag="BSU26449" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_009513983.1" /translation="MAQADVRQSKRESQSNSAAFGKIYSEITPLHRLHDFKLVLLNEA GIKRTDLIYGLVIFISFRLLWANKSTRVYSMCIAHDRI*" gene 2572132..2572380 /locus_tag="BSU_26449" /old_locus_tag="BSU26449" S_feature complement(2572309..2573356) /Source="Nicolas_S_feature" /locus_tag="new_2706711_2707758_c" /HighExp="Diami, C30, dia15, dia5, Lbstat, S8, C90, G180, H2O2, G135" /AntisenseName="yrkN" /AntisenseCor="0.40539464433869998" /AntisenseRegPval="-11.3" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA, SigA, SigA" /TUshortPSig="1, 0.962, 1, 0.998" /TUlongSig="NA" /TUlongPSig="NA" /label="S985" CDS 2572725..2573282 /gene="yrkN" /locus_tag="BSU_26450" /old_locus_tag="BSU26450" /EC_number="2.3.-.-" /function="16.8: Protect" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 18175906; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative N-acetyltransferase" /protein_id="NP_390522.1" /db_xref="EnsemblGenomes-Gn:BSU26450" /db_xref="EnsemblGenomes-Tr:CAB14586" /db_xref="GOA:P54441" /db_xref="InterPro:IPR000182" /db_xref="InterPro:IPR016181" /db_xref="SubtiList:BG11780" /db_xref="UniProtKB/Swiss-Prot:P54441" /translation="MKTKNEPKVILELAKESDLPEFQKKLQEAFAIAVIETFGDCEDG PIPSDNDVQESFNAPGAVVYHILQDGKNVGGAVVRINSQTNHNSLDLFYVSPEYHSQG IGLSAWKAIEAQYPDTVLWETVTPYFEKRNINFYVNKCGFHIVEFYNEHHSNPHMHRN GREDDKPLLNDDDFFRFVKIMKKKD*" gene 2572725..2573282 /gene="yrkN" /locus_tag="BSU_26450" /old_locus_tag="BSU26450" S_feature 2573283..2573405 /Source="Nicolas_S_feature" /locus_tag="new_2707685_2707807" /HighExp="S8, Sw, C30, S7, BC, C90, Lbstat, Mal, LoTm, dia15" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="NA" /TUshortPSig="NA" /TUlongSig="NA" /TUlongPSig="NA" /label="S986" S_feature complement(2573358..2573772) /Source="Nicolas_S_feature" /locus_tag="new_2707760_2708174_c" /HighExp="M0t90, M40t90, Lbstat, dia5, LPhT, dia15, M9-stat, Lbtran, C90, Etha" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA, SigA, SigA" /TUshortPSig="1, 0.962, 1, 0.998" /TUlongSig="NA" /TUlongPSig="NA" /label="S987" downshifts complement(2573401) /Source="Nicolas_upshifts" /id="D1360" /incds=0 /nref=81 /ntot=255 /MaxReadThrough="5.45539" /MaxDrop="5.6563" /score="-3.35079978" /energy="-23.7" /TU="U2041,U2042,U2044,U2045" /idTUdmin="U2042" /TUdmin="-182" /isTUend="FALSE" CDS complement(2573773..2574297) /gene="yrkL" /locus_tag="BSU_26470" /old_locus_tag="BSU26470" /EC_number="1.6.-.-" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 11053405; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative NAD(P)H oxidoreductase" /protein_id="NP_390524.2" /db_xref="EnsemblGenomes-Gn:BSU26470" /db_xref="EnsemblGenomes-Tr:CAB14588" /db_xref="GOA:P54439" /db_xref="InterPro:IPR003680" /db_xref="InterPro:IPR029039" /db_xref="SubtiList:BG11778" /db_xref="UniProtKB/Swiss-Prot:P54439" /translation="MKTLVIVIHPNLETSVVNKTWMNRLKQEKDITVHDLYGEYPNFI IDVEKEQQLLLDHERIVFQFPMYWYSSPALLKQWEDDVLTHGWAYGTGGTKLHGKELL LAISLGAQESDYQAGGEYNITISELIRPFQVTANYIGMRFLPAFTQYGTLHLSKEDVK NSAERLVDYLKAEH*" gene complement(2573773..2574297) /gene="yrkL" /locus_tag="BSU_26470" /old_locus_tag="BSU26470" promotor_-35 2574145..2574152 /Source="Nicolas_upshift_promotors" /id="U2040" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.972027972027972" /psig="0.996003996003996" /xcortree=458 /SigmaFactorBS="cgatacgctcatgatctaacaggagctgCTGCTCTTtttcta catcAATGATAAAATTAGGGTATTcaccgtacaggtcatgaaccgtaatgtctttctc t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2574163..2574182 /Source="Nicolas_upshift_promotors" /id="U2040" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.972027972027972" /psig="0.996003996003996" /xcortree=458 /SigmaFactorBS="cgatacgctcatgatctaacaggagctgCTGCTCTTtttcta catcAATGATAAAATTAGGGTATTcaccgtacaggtcatgaaccgtaatgtctttctc t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2574177 /Source="Nicolas_upshifts" /id="U2040" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.972027972027972" /psig="0.996003996003996" /xcortree=458 /SigmaFactorBS="cgatacgctcatgatctaacaggagctgCTGCTCTTtttcta catcAATGATAAAATTAGGGTATTcaccgtacaggtcatgaaccgtaatgtctttctc t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" S_feature complement(2574298..2574385) /Source="Nicolas_S_feature" /locus_tag="new_2708700_2708787_c" /HighExp="dia5, Etha, dia15, M9-stat, M0t90, Lbtran, Diami, C90, T3.0H, T3.30H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA, SigA, SigA" /TUshortPSig="1, 0.962, 1, 0.998" /TUlongSig="NA" /TUlongPSig="NA" /label="S988" promotor_-10 complement(2574380..2574399) /Source="Nicolas_upshift_promotors" /id="U2041" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.987012987012987" /psig=1 /xcortree=2050 /SigmaFactorBS="tcatcattgattttggtgcccaatTAGTTGCCctgaattcat gaaaAAGGATAAAATAGGTGTAAAtaaagttgctattttaaaattagaatcaattcat t" /listShort="S988, yrkL, S987, S985" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2574385) /Source="Nicolas_upshifts" /id="U2041" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.987012987012987" /psig=1 /xcortree=2050 /SigmaFactorBS="tcatcattgattttggtgcccaatTAGTTGCCctgaattcat gaaaAAGGATAAAATAGGTGTAAAtaaagttgctattttaaaattagaatcaattcat t" /listShort="S988, yrkL, S987, S985" /GFF_Attribute="listLong" S_feature complement(2574387..2574540) /Source="Nicolas_S_feature" /locus_tag="new_2708789_2708942_c" /HighExp="M0t90, M9-stat, Lbstat, M40t90, T1.30H, C90, Lbtran, T0.30H, dia15, BC" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA, SigA" /TUshortPSig="0.962, 1, 0.998" /TUlongSig="NA" /TUlongPSig="NA" /label="S989" promotor_-35 complement(2574414..2574421) /Source="Nicolas_upshift_promotors" /id="U2041" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.987012987012987" /psig=1 /xcortree=2050 /SigmaFactorBS="tcatcattgattttggtgcccaatTAGTTGCCctgaattcat gaaaAAGGATAAAATAGGTGTAAAtaaagttgctattttaaaattagaatcaattcat t" /listShort="S988, yrkL, S987, S985" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2574541..2575017) /gene="yrkK" /locus_tag="BSU_26480" /old_locus_tag="BSU26480" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative integral inner membrane protein" /protein_id="NP_390525.2" /db_xref="EnsemblGenomes-Gn:BSU26480" /db_xref="EnsemblGenomes-Tr:CAB14589" /db_xref="GOA:P54438" /db_xref="InterPro:IPR025671" /db_xref="SubtiList:BG11777" /db_xref="UniProtKB/Swiss-Prot:P54438" /translation="MVYFVAFFCFAITLHNIEEAIWLPEWSQQSSKFQKPVTSNEFHF AVIVITMLAYLSAFGFLYMPESDIAKWIFIGFLGSMVINAIFPHLIATVVMKKYAPGL LTGLLLNIPVNSLVIYQMFLKNLIVWKELIISTLVVGIILLALIPLLFKVGDKVSP*" gene complement(2574541..2575017) /gene="yrkK" /locus_tag="BSU_26480" /old_locus_tag="BSU26480" promotor_-10 complement(2575053..2575072) /Source="Nicolas_upshift_promotors" /id="U2042" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.553446553446553" /psig="0.962037962037962" /xcortree=3147 /SigmaFactorBS="caactactaaggcagattcttctctcttttaacaCCATATCC aatcagcctcaaaTGTAATATAATGTTGCCAAAccatattggttgtggcaccgaggag g" /listShort="yrkK, S989, S988, yrkL, S987, S985" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2575067) /Source="Nicolas_upshifts" /id="U2042" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.553446553446553" /psig="0.962037962037962" /xcortree=3147 /SigmaFactorBS="caactactaaggcagattcttctctcttttaacaCCATATCC aatcagcctcaaaTGTAATATAATGTTGCCAAAccatattggttgtggcaccgaggag g" /listShort="yrkK, S989, S988, yrkL, S987, S985" /GFF_Attribute="listLong" S_feature complement(2575069..2575599) /Source="Nicolas_S_feature" /locus_tag="new_2709471_2710001_c" /HighExp="Diami, dia15, S8, G180, Etha, G135, S6, S0, G150, LBGexp" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="1, 0.998" /TUlongSig="NA" /TUlongPSig="NA" /label="S990" promotor_-35 complement(2575086..2575093) /Source="Nicolas_upshift_promotors" /id="U2042" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.553446553446553" /psig="0.962037962037962" /xcortree=3147 /SigmaFactorBS="caactactaaggcagattcttctctcttttaacaCCATATCC aatcagcctcaaaTGTAATATAATGTTGCCAAAccatattggttgtggcaccgaggag g" /listShort="yrkK, S989, S988, yrkL, S987, S985" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2575600..2576385) /gene="yrkJ" /locus_tag="BSU_26490" /old_locus_tag="BSU26490" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative permease" /protein_id="NP_390526.1" /db_xref="EnsemblGenomes-Gn:BSU26490" /db_xref="EnsemblGenomes-Tr:CAB14590" /db_xref="GOA:P54437" /db_xref="InterPro:IPR002781" /db_xref="SubtiList:BG11776" /db_xref="UniProtKB/Swiss-Prot:P54437" /translation="MDIAFITTLFIIGFIGAFISGMIGIGGAVINYPMLLYIPSLVGV MSLTAHEVSGIGAIQVFFATLGGVWAYRKSGLINKTLIIYMGSSILLGSVLGSYFSHY ISEKGINFIYGILAIIAVILMFIPKKGQKGQEHSEDKEVIFNKWLASSLAFIIGGVSG ILGAGGAFILVPIMLSILNIPVRVTVASSLAITFLSSIGATVGKVITGQVLFVPALVL MITSLIASPIGASVGQKVNTKFLQWVLAQLIGATAIKIWLELL*" gene complement(2575600..2576385) /gene="yrkJ" /locus_tag="BSU_26490" /old_locus_tag="BSU26490" CDS complement(2576446..2576673) /gene="yrkI" /locus_tag="BSU_26500" /old_locus_tag="BSU26500" /function="5.5: Sulfur metabolism" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 9555915; Product type c: carrier" /codon_start=1 /transl_table=11 /product="putative sulfur-carrier protein" /protein_id="NP_390527.1" /db_xref="EnsemblGenomes-Gn:BSU26500" /db_xref="EnsemblGenomes-Tr:CAB14591" /db_xref="GOA:P54436" /db_xref="InterPro:IPR001455" /db_xref="InterPro:IPR036868" /db_xref="SubtiList:BG11775" /db_xref="UniProtKB/Swiss-Prot:P54436" /translation="MKSDKVLDAKGLACPMPIVRTKKAMNELESGQILEVHATDKGAK NDLTAWSKSGGHDLLEQTDEGDILKFWIQKG*" gene complement(2576446..2576673) /gene="yrkI" /locus_tag="BSU_26500" /old_locus_tag="BSU26500" downshifts complement(2576470) /Source="Nicolas_upshifts" /id="D1361" /incds=0 /nref=4 /ntot=22 /MaxReadThrough="5.31659" /MaxDrop="3.95633" /score="-3.35079978" /energy="-23.7" /TU="U2044,U2045" /idTUdmin="U2046" /TUdmin=3085 /isTUend="FALSE" CDS complement(2576707..2577840) /gene="yrkH" /locus_tag="BSU_26510" /old_locus_tag="BSU26510" /EC_number="3.-.-.-" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative sulfur transferase / hydrolase" /protein_id="NP_390528.2" /db_xref="EnsemblGenomes-Gn:BSU26510" /db_xref="EnsemblGenomes-Tr:CAB14592" /db_xref="InterPro:IPR001279" /db_xref="InterPro:IPR001763" /db_xref="InterPro:IPR036866" /db_xref="InterPro:IPR036873" /db_xref="SubtiList:BG11774" /db_xref="UniProtKB/Swiss-Prot:P54435" /translation="MKHDRKGNDPKRSDKKIFNKEPLFILDVRNENDFSDWKIEGHDF DHLNVPYFDLLDGVEDILEKIPSDKEVLVVCAKEGSSVMVSEMLSEAGHSVSYLKGGM KAWSEHLEPVKVGDLKDGGEMYQFVRIGKGCLSYMVISNGEAAIIDATRMVNFFIDFA KGKGATITHVFDTHLHADHISGGRVIAEKTKATYWLPPKDAEEVEFDYQPLEEGNDII IGNTTIKIQPIYSPGHTIGSTSFIVDDQYLLSGDILFIDSIGRPDLAGMAEDWVGDLR KTLYSRYKALSKDLIVLPAHFMIIDELNENGSVGKQLSTLFSENHGLNIADETEFRHL VTDHLPPQPNAYQEIRETNMGKISPDEEKQREMEIGPNRCAIR*" gene complement(2576707..2577840) /gene="yrkH" /locus_tag="BSU_26510" /old_locus_tag="BSU26510" misc_feature complement(2577542..2577557) /Source="Nicolas_upshift_promotors" /id="U2043" /multdbtbs="-" /comp="M19" /sig="Sig-" /pcomp="0.410589410589411" /psig="0.477522477522478" /xcortree=1482 /SigmaFactorBS="aaaagaaggttcatccgtcatggtatccgaaatgctttctga agcaggtcattctgTATCCTACCTTAAGGGtggaatgaaagcatggagcgaacattta g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(2577553) /Source="Nicolas_upshifts" /id="U2043" /multdbtbs="-" /comp="M19" /sig="Sig-" /pcomp="0.410589410589411" /psig="0.477522477522478" /xcortree=1482 /SigmaFactorBS="aaaagaaggttcatccgtcatggtatccgaaatgctttctga agcaggtcattctgTATCCTACCTTAAGGGtggaatgaaagcatggagcgaacattta g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" S_feature complement(2577841..2578174) /Source="Nicolas_S_feature" /locus_tag="new_2712243_2712576_c" /HighExp="Diami, dia15, Sw, BC, S0, G180, dia5, G135, M9-stat, S8" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.99950300000000003" /TUshortSig="SigA, SigA" /TUshortPSig="1, 0.998" /TUlongSig="NA" /TUlongPSig="NA" /label="S991" CDS complement(2578175..2578732) /gene="yrkF" /locus_tag="BSU_26530" /old_locus_tag="BSU26530" /function="5.5: Sulfur metabolism" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 22720735; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative rhodanese-related sulfur transferase" /protein_id="NP_390530.1" /db_xref="EnsemblGenomes-Gn:BSU26530" /db_xref="EnsemblGenomes-Tr:CAB14594" /db_xref="InterPro:IPR001455" /db_xref="InterPro:IPR001763" /db_xref="InterPro:IPR036868" /db_xref="InterPro:IPR036873" /db_xref="SubtiList:BG11772" /db_xref="UniProtKB/Swiss-Prot:P54433" /translation="MMKATIVLDAKGLACPMPIVKTKKRMKDLKAGEVLEIHATDKGS TADLEAWAKSTGHEYLGTEAEGEILRHFLRKGGEHSSENASSIPEISLEAFKQKVDSD ESLNILDVREIEEYEKAHIPGVVHIPLGEVEKRANELNENDEIYIICHSGRRSEMAAR TMKKQGFKKVINVVPGMRDWTGKTE*" gene complement(2578175..2578732) /gene="yrkF" /locus_tag="BSU_26530" /old_locus_tag="BSU26530" S_feature complement(2578733..2578917) /Source="Nicolas_S_feature" /locus_tag="new_2713135_2713319_c" /HighExp="Diami, dia15, Sw, BC, S8, dia5, G180, S7, S0, S6" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.12629799999999999" /TUshortSig="SigA, SigA" /TUshortPSig="1, 0.998" /TUlongSig="NA" /TUlongPSig="NA" /label="S992" CDS complement(2578918..2579400) /gene="yrkE" /locus_tag="BSU_26540" /old_locus_tag="BSU26540" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative protein involved in sulfur metabolism (DsrE-like)" /protein_id="NP_390531.1" /db_xref="EnsemblGenomes-Gn:BSU26540" /db_xref="EnsemblGenomes-Tr:CAB14595" /db_xref="InterPro:IPR027396" /db_xref="InterPro:IPR032836" /db_xref="SubtiList:BG11771" /db_xref="UniProtKB/Swiss-Prot:P54432" /translation="MTEQTKRTTIVLFSGDYDKAMAAYIIANGAAAYDHEVTIFHTFW GFNALRKEELIPVKKGFLEKMFGKMMPRGADKMGLSKMNFAGMGPKMIKNVMKKHNVL TLPQLIEMAQEQGVKLVACTMTMDLLGLQEKELLDDIDYAGVAAYLADAEEGSVNLFI *" gene complement(2578918..2579400) /gene="yrkE" /locus_tag="BSU_26540" /old_locus_tag="BSU26540" S_feature complement(2579401..2579509) /Source="Nicolas_S_feature" /locus_tag="new_2713803_2713911_c" /HighExp="Diami, dia15, Sw, BC, dia5, S8, G180, S6, Oxctl, M9-stat" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="1, 0.998" /TUlongSig="NA" /TUlongPSig="NA" /label="S993" CDS complement(2579547..2579738) /gene="yrkD" /locus_tag="BSU_26550" /old_locus_tag="BSU26550" /function="5.5: Sulfur metabolism" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 21339296; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative metal-sensitive transcriptional regulator involved in sulfur metabolism" /protein_id="NP_390532.1" /db_xref="EnsemblGenomes-Gn:BSU26550" /db_xref="EnsemblGenomes-Tr:CAB14596" /db_xref="GOA:P54431" /db_xref="InterPro:IPR003735" /db_xref="SubtiList:BG11770" /db_xref="UniProtKB/Swiss-Prot:P54431" /translation="MMEQGKDCREVVTQLAASRNAIDRAMGLIVSTNLEHCVRESLEK GEDTQNLVKEAVDLLVKSR*" gene complement(2579547..2579738) /gene="yrkD" /locus_tag="BSU_26550" /old_locus_tag="BSU26550" downshifts complement(2579554) /Source="Nicolas_upshifts" /id="D1362" /incds=0 /nref=153 /ntot=252 /MaxReadThrough="8.17686" /MaxDrop="5.42995" /score="-6.39526496" /energy="-7.9" /TU="U2044,U2045" /idTUdmin="U2046" /TUdmin=1 /isTUend="TRUE" S_feature complement(2579739..2579828) /Source="Nicolas_S_feature" /locus_tag="new_2714141_2714230_c" /HighExp="Diami, dia15, S6, S7, S8, Etha, dia5, S5, BC, M9-stat" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA, SigK" /TUshortPSig="1, 0.998, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S994" CDS complement(2579829..2580146) /gene="yrzM" /locus_tag="BSU_26558" /old_locus_tag="BSU26558" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /pseudo /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /db_xref="PSEUDO:CAX52666.1" /translation="MIIIATYRRYYPITGISCIHKDKLEAMDITILDIRHYNDVANFS DNIILNIPYAYLKRFYLEIPRDKIHIIARDRVELNLGVRFLKRKGIHVNSYELATCKC KNK*" gene complement(2579829..2580146) /gene="yrzM" /locus_tag="BSU_26558" /old_locus_tag="BSU26558" /pseudo promotor_-10 complement(2579935..2579954) /Source="Nicolas_upshift_promotors" /id="U2044" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.661338661338661" /psig=1 /xcortree=1899 /SigmaFactorBS="aatattattttaaacatcccatatgcgtatctaaaacgTTTT TATttagagattccaCGTGATAAAATACACATAATagctcgtgaccgggtggaattaa a" /listShort="S994, yrkD, S993, yrkE, S992, yrkF, S991, yrkH, yrkI, yrkJ, S990, yrkK, S989, S988, yrkL, S987, S985" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2579951) /Source="Nicolas_upshifts" /id="U2044" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.661338661338661" /psig=1 /xcortree=1899 /SigmaFactorBS="aatattattttaaacatcccatatgcgtatctaaaacgTTTT TATttagagattccaCGTGATAAAATACACATAATagctcgtgaccgggtggaattaa a" /listShort="S994, yrkD, S993, yrkE, S992, yrkF, S991, yrkH, yrkI, yrkJ, S990, yrkK, S989, S988, yrkL, S987, S985" /GFF_Attribute="listLong" promotor_-35 complement(2579967..2579973) /Source="Nicolas_upshift_promotors" /id="U2044" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.661338661338661" /psig=1 /xcortree=1899 /SigmaFactorBS="aatattattttaaacatcccatatgcgtatctaaaacgTTTT TATttagagattccaCGTGATAAAATACACATAATagctcgtgaccgggtggaattaa a" /listShort="S994, yrkD, S993, yrkE, S992, yrkF, S991, yrkH, yrkI, yrkJ, S990, yrkK, S989, S988, yrkL, S987, S985" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2580188..2580403) /gene="yrzN" /locus_tag="BSU_26559" /old_locus_tag="BSU26559" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /pseudo /codon_start=1 /transl_table=11 /product="hypothetical protein" /db_xref="PSEUDO:CAX52667.1" /translation="MINKADLKLNRLIALFEFLLAELALSNVSIFSIRGYRNESISSK KVTFTLDYIPMGVYYCFVNKQRVNKVV*" gene complement(2580188..2580403) /gene="yrzN" /locus_tag="BSU_26559" /old_locus_tag="BSU26559" /pseudo promotor_-10 complement(2580216..2580235) /Source="Nicolas_upshift_promotors" /id="U2045" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.728271728271728" /psig="0.998001998001998" /xcortree=1794 /SigmaFactorBS="tgaatctatcagctcaaagaaagtaactttcacACTTGACTa tatacctatggggGTATATTATTGTTTTGTGAAtaaacaaagagttaataaggtggtg t" /listShort="yrzM, S994, yrkD, S993, yrkE, S992, yrkF, S991, yrkH, yrkI, yrkJ, S990, yrkK, S989, S988, yrkL, S987, S985" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2580230) /Source="Nicolas_upshifts" /id="U2045" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.728271728271728" /psig="0.998001998001998" /xcortree=1794 /SigmaFactorBS="tgaatctatcagctcaaagaaagtaactttcacACTTGACTa tatacctatggggGTATATTATTGTTTTGTGAAtaaacaaagagttaataaggtggtg t" /listShort="yrzM, S994, yrkD, S993, yrkE, S992, yrkF, S991, yrkH, yrkI, yrkJ, S990, yrkK, S989, S988, yrkL, S987, S985" /GFF_Attribute="listLong" promotor_-35 complement(2580250..2580257) /Source="Nicolas_upshift_promotors" /id="U2045" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.728271728271728" /psig="0.998001998001998" /xcortree=1794 /SigmaFactorBS="tgaatctatcagctcaaagaaagtaactttcacACTTGACTa tatacctatggggGTATATTATTGTTTTGTGAAtaaacaaagagttaataaggtggtg t" /listShort="yrzM, S994, yrkD, S993, yrkE, S992, yrkF, S991, yrkH, yrkI, yrkJ, S990, yrkK, S989, S988, yrkL, S987, S985" /GFF_Attribute="listLong" /label="promotor_-35" S_feature complement(2580404..2580530) /Source="Nicolas_S_feature" /locus_tag="new_2714806_2714932_c" /HighExp="S6, S7, S8, S5, BT, B36, G/S, BC, Pyr, B60" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.114547" /TUshortSig="SigK, SigA" /TUshortPSig="1, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S995" CDS complement(2580531..2581091) /gene="yrkC" /locus_tag="BSU_26560" /old_locus_tag="BSU26560" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 10704478; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative enzyme; cupin family" /protein_id="NP_390533.1" /db_xref="EnsemblGenomes-Gn:BSU26560" /db_xref="EnsemblGenomes-Tr:CAB14597" /db_xref="GOA:P54430" /db_xref="InterPro:IPR011051" /db_xref="InterPro:IPR013096" /db_xref="InterPro:IPR014710" /db_xref="SubtiList:BG11769" /db_xref="UniProtKB/Swiss-Prot:P54430" /translation="MYYNPFSPQCYYYVTVPMYNDGRSVYWTIPNEMEKVHRGADLRS SYEDRNLLLKDYGPKPFVVNINRATKQNNTFRTALWTGKHFQVTLMSLGIGEDIGLEI HPNVDQFLRIEQGRGIVKMGKSKDHLNFQRNVYDDSAIVVPAGTWHNVINTGNTPLKL YSIYAPPNHPFGTVHETKADAVAAED*" gene complement(2580531..2581091) /gene="yrkC" /locus_tag="BSU_26560" /old_locus_tag="BSU26560" CDS complement(2581108..2581284) /locus_tag="BSU_26569" /old_locus_tag="BSU26569" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_009513984.1" /translation="MLTKASEIQHLENDYKVGDKLFIHESNGDRTFIFVFNMSFLDLA HSLNKCIGYYHKNL*" gene complement(2581108..2581284) /locus_tag="BSU_26569" /old_locus_tag="BSU26569" promotor_-10 complement(2581118..2581137) /Source="Nicolas_upshift_promotors" /id="U2046" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1282 /SigmaFactorBS="catttttgtgtttaatatgagttttcttgaTTTAGCACACtc ccttaataaaTGCATAGGATACTATCACAAaaatttataattgcggggatcaaaaaat g" /listShort="yrkC, S995, yrzN, yrzM, S994, yrkD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2581129) /Source="Nicolas_upshifts" /id="U2046" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1282 /SigmaFactorBS="catttttgtgtttaatatgagttttcttgaTTTAGCACACtc ccttaataaaTGCATAGGATACTATCACAAaaatttataattgcggggatcaaaaaat g" /listShort="yrkC, S995, yrzN, yrzM, S994, yrkD" /GFF_Attribute="listLong" S_feature complement(2581131..2581316) /Source="Nicolas_S_feature" /locus_tag="new_2715533_2715718_c" /HighExp="BC, Sw, S3, dia15, Etha, S4, S5, H2O2, LBGtran, LBGstat" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.49093999999999999" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S996" promotor_-35 complement(2581150..2581159) /Source="Nicolas_upshift_promotors" /id="U2046" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1282 /SigmaFactorBS="catttttgtgtttaatatgagttttcttgaTTTAGCACACtc ccttaataaaTGCATAGGATACTATCACAAaaatttataattgcggggatcaaaaaat g" /listShort="yrkC, S995, yrzN, yrzM, S994, yrkD" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2581317..2581463) /gene="yrkB" /locus_tag="BSU_26570" /old_locus_tag="BSU26570" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="NP_390534.1" /db_xref="EnsemblGenomes-Gn:BSU26570" /db_xref="EnsemblGenomes-Tr:CAB14598" /db_xref="SubtiList:BG11768" /db_xref="UniProtKB/Swiss-Prot:P54429" /translation="MLLKNWPSRRIQRDKSKRAGIGGTNNRIPYTLLLCYVNVQKPFR IVDL*" gene complement(2581317..2581463) /gene="yrkB" /locus_tag="BSU_26570" /old_locus_tag="BSU26570" CDS complement(2581633..2582454) /gene="bltR" /locus_tag="BSU_26580" /old_locus_tag="BSU26580" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:7608059, 9083003, 10200972, 21954605" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7608059, 9083003, 10200972, 21954605; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator (polyamine metabolism)" /protein_id="NP_390535.1" /db_xref="EnsemblGenomes-Gn:BSU26580" /db_xref="EnsemblGenomes-Tr:CAB14599" /db_xref="GOA:P39842" /db_xref="InterPro:IPR000551" /db_xref="InterPro:IPR009061" /db_xref="InterPro:IPR011256" /db_xref="SubtiList:BG10904" /db_xref="UniProtKB/Swiss-Prot:P39842" /translation="MSEDVKKYFTTGEFSKLCRVKKQTLFHYDEIGLFSPEIKKENGY RYYSYHQFETFQVISLFKELGVPLKEIKCLIKGKTPDKILHVLKEKSIEIDKKINELK QLQTILQTKVTLTEQALETDFSSISFEYLNEETFMLSRKTLNLPERKYVAAISELIHE VQQYELDEGYPIGGIFAREQILEKDFYNYSYFYIKVKDGAENINYHVRPKGLYAVGYE IGGNTEEAYRRIIEFIERNGMQIGENAYEEYMLDEMVVDGYENTYAKILLQVKEV*" gene complement(2581633..2582454) /gene="bltR" /locus_tag="BSU_26580" /old_locus_tag="BSU26580" promotor_-35 2582462..2582469 /Source="Nicolas_upshift_promotors" /id="U2048" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.983016983016983" /psig="0.997002997002997" /xcortree=1531 /SigmaFactorBS="acttcttaacatcttcgctcataaaaaccTCCTTGACtatac ggtaaccataTACCTTATGATTTGATTGTActtgaaaaaagcttcaagcgaaaaggat a" /listShort="blt" /GFF_Attribute="listLong" /label="promotor_-35" misc_feature complement(2582464..2582483) /Source="Nicolas_upshift_promotors" /id="U2047" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.561438561438561" /psig="0.966033966033966" /xcortree=1901 /SigmaFactorBS="tttttacctatccttttcgcttgaagcttttttcaagtacaa tcaaatcataaggtatATGGTTACCGTATAGTCAAGgaggtttttatgagcgaagatg t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(2582481) /Source="Nicolas_upshifts" /id="U2047" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.561438561438561" /psig="0.966033966033966" /xcortree=1901 /SigmaFactorBS="tttttacctatccttttcgcttgaagcttttttcaagtacaa tcaaatcataaggtatATGGTTACCGTATAGTCAAGgaggtttttatgagcgaagatg t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" S_feature complement(2582483..2584487) /Source="Nicolas_S_feature" /locus_tag="new_2716885_2718889_c" /HighExp="BC, Sw, Salt, Mal, T4.0H, M9-stat, T3.30H, G180, G135, MG 5" /AntisenseName="blt" /AntisenseCor="0.56943492854420497" /AntisenseRegPval="-23.8" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S997" promotor_-10 2582485..2582504 /Source="Nicolas_upshift_promotors" /id="U2048" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.983016983016983" /psig="0.997002997002997" /xcortree=1531 /SigmaFactorBS="acttcttaacatcttcgctcataaaaaccTCCTTGACtatac ggtaaccataTACCTTATGATTTGATTGTActtgaaaaaagcttcaagcgaaaaggat a" /listShort="blt" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2582493 /Source="Nicolas_upshifts" /id="U2048" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.983016983016983" /psig="0.997002997002997" /xcortree=1531 /SigmaFactorBS="acttcttaacatcttcgctcataaaaaccTCCTTGACtatac ggtaaccataTACCTTATGATTTGATTGTActtgaaaaaagcttcaagcgaaaaggat a" /listShort="blt" /GFF_Attribute="listLong" CDS 2582571..2583773 /gene="blt" /locus_tag="BSU_26590" /old_locus_tag="BSU26590" /function="16.1: Circulate" /function="16.4: Excrete" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:9083003, 10200972, 10359661, 12793527, 15849754, 16850406, 19114526, 21954605" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9083003, 10200972, 10359661, 12793527, 15849754, 16850406, 19114526, 21954605; Product type t: transporter" /codon_start=1 /transl_table=11 /product="efflux transporter (promiscuous, acetylated polyamines efflux)" /protein_id="NP_390536.1" /db_xref="EnsemblGenomes-Gn:BSU26590" /db_xref="EnsemblGenomes-Tr:CAB14600" /db_xref="GOA:P39843" /db_xref="InterPro:IPR001958" /db_xref="InterPro:IPR004734" /db_xref="InterPro:IPR005829" /db_xref="InterPro:IPR011701" /db_xref="InterPro:IPR020846" /db_xref="InterPro:IPR036259" /db_xref="SubtiList:BG10905" /db_xref="UniProtKB/Swiss-Prot:P39843" /translation="MKKSINEQKTIFIILLSNIFVAFLGIGLIIPVMPSFMKIMHLSG STMGYLVAAFAISQLITSPFAGRWVDRFGRKKMIILGLLIFSLSELIFGLGTHVSIFY FSRILGGVSAAFIMPAVTAYVADITTLKERSKAMGYVSAAISTGFIIGPGAGGFIAGF GIRMPFFFASAIALIAAVTSVFILKESLSIEERHQLSSHTKESNFIKDLKRSIHPVYF IAFIIVFVMAFGLSAYETVFSLFSDHKFGFTPKDIAAIITISSIVAVVIQVLLFGKLV NKLGEKRMIQLCLITGAILAFVSTVMSGFLTVLLVTCFIFLAFDLLRPALTAHLSNMA GNQQGFVAGMNSTYTSLGNIFGPALGGILFDLNIHYPFLFAGFVMIVGLGLTMVWKEK KNDAAALN*" gene 2582571..2583773 /gene="blt" /locus_tag="BSU_26590" /old_locus_tag="BSU26590" CDS 2583942..2584400 /gene="bltD" /locus_tag="BSU_26600" /old_locus_tag="BSU26600" /EC_number="2.3.1.57" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:10200972, 10359661, 12793527, 9083003, 16210326, 21954605, 28197687" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10200972, 10359661, 12793527, 9083003, 16210326, 21954605, 28197687; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="spermine/spermidine acetyltransferase" /protein_id="NP_390537.1" /db_xref="EnsemblGenomes-Gn:BSU26600" /db_xref="EnsemblGenomes-Tr:CAB14601" /db_xref="GOA:P39909" /db_xref="InterPro:IPR000182" /db_xref="InterPro:IPR016181" /db_xref="InterPro:IPR027455" /db_xref="SubtiList:BG10906" /db_xref="UniProtKB/Swiss-Prot:P39909" /translation="MSINIKAVTDDNRAAILDLHVSQNQLSYIESTKVCLEDAKECHY YKPVGLYYEGDLVGFAMYGLFPEYDEDNKNGRVWLDRFFIDERYQGKGLGKKMLKALI QHLAELYKCKRIYLSIFENNIHAIRLYQRFGFQFNGELDFNGEKVMVKEL*" gene 2583942..2584400 /gene="bltD" /locus_tag="BSU_26600" /old_locus_tag="BSU26600" downshifts complement(2584532) /Source="Nicolas_upshifts" /id="D1363" /incds=0 /nref=77 /ntot=211 /MaxReadThrough="5.09534" /MaxDrop="4.8114" /score="-0.00168005652" /energy="-10.7" /TU="U2049" /idTUdmin="U2051" /TUdmin=3845 /isTUend="FALSE" CDS complement(2584557..2585861) /gene="yrkA" /locus_tag="BSU_26610" /old_locus_tag="BSU26610" /function="16.8: Protect" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type s: structure" /codon_start=1 /transl_table=11 /product="putative membrane associated protein" /protein_id="NP_390538.1" /db_xref="EnsemblGenomes-Gn:BSU26610" /db_xref="EnsemblGenomes-Tr:CAB14602" /db_xref="GOA:P54428" /db_xref="InterPro:IPR000644" /db_xref="InterPro:IPR002550" /db_xref="InterPro:IPR005170" /db_xref="InterPro:IPR016169" /db_xref="InterPro:IPR036318" /db_xref="SubtiList:BG11767" /db_xref="UniProtKB/Swiss-Prot:P54428" /translation="MTTINLIIFTLLIVLTAFFVATEFAIVKIRSSKIDQLILEGKKG AISAKKVITHLDEYLSACQLGITVTALGIGWVGESTFEVILHPLFAHFHVSETVSHVL ILVIAFVMATFLHVVVGELAPKTLAIQKAETITLLTAKPIIWFYRILFPFIWFLNGSA RFIVGLFGLKPASEHELAHSEEELRILLSESYKSGEINQNELKYVNNIFEFDERIAKE IMIPRREIVAISSEDSYETIVKIIKTESYTRYPVLNGDKDSIIGFINAKEFLSAYIDT DQKIKEDFKLENHINPVIHVIESVPIHDVLVKMQKERTHIAILVDEYGGTSGLVTAED ILEEIVGEIRDEFDKDEVPNIRKVNDNHYILDSKVLIEDVNDLLGTTLASDEVDTIGG WFMTQQIDAAVGSVIEADGYIFKVHETVGRHINYLEIVRKKE*" gene complement(2584557..2585861) /gene="yrkA" /locus_tag="BSU_26610" /old_locus_tag="BSU26610" S_feature complement(2585862..2585941) /Source="Nicolas_S_feature" /locus_tag="new_2720264_2720343_c" /HighExp="BC, Sw, MG 15, Mal, Salt, MG 25, MG-0.2, MG 45, MG 5, M/G" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S998" promotor_-10 complement(2585927..2585946) /Source="Nicolas_upshift_promotors" /id="U2049" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.633366633366633" /psig=1 /xcortree=1760 /SigmaFactorBS="atacggaaaaagatgattatttacatcattcagAGTTGATTt taggttcttttgaACTTATAATGTTATATATACtgttttttgtttattcaataaatat t" /listShort="S998, yrkA, S997, bltR, yrkB, S996, yrkC, S995" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2585941) /Source="Nicolas_upshifts" /id="U2049" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.633366633366633" /psig=1 /xcortree=1760 /SigmaFactorBS="atacggaaaaagatgattatttacatcattcagAGTTGATTt taggttcttttgaACTTATAATGTTATATATACtgttttttgtttattcaataaatat t" /listShort="S998, yrkA, S997, bltR, yrkB, S996, yrkC, S995" /GFF_Attribute="listLong" promotor_-35 complement(2585961..2585968) /Source="Nicolas_upshift_promotors" /id="U2049" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.633366633366633" /psig=1 /xcortree=1760 /SigmaFactorBS="atacggaaaaagatgattatttacatcattcagAGTTGATTt taggttcttttgaACTTATAATGTTATATATACtgttttttgtttattcaataaatat t" /listShort="S998, yrkA, S997, bltR, yrkB, S996, yrkC, S995" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2586124..2586267) /gene="yrzO" /locus_tag="BSU_26619" /old_locus_tag="BSU26619" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="YP_003097765.1" /db_xref="EnsemblGenomes-Gn:BSU26619" /db_xref="EnsemblGenomes-Tr:CAX52668" /db_xref="InterPro:IPR025417" /db_xref="UniProtKB/Swiss-Prot:C0H458" /translation="MFEGLLFFISAGIVCELAAINRNGRKNIKQQAELIQILKENLYK DIK*" gene complement(2586124..2586267) /gene="yrzO" /locus_tag="BSU_26619" /old_locus_tag="BSU26619" CDS complement(2586285..2587250) /gene="yrdR" /locus_tag="BSU_26620" /old_locus_tag="BSU26620" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative efflux transporter" /protein_id="NP_390539.1" /db_xref="EnsemblGenomes-Gn:BSU26620" /db_xref="EnsemblGenomes-Tr:CAB14603" /db_xref="GOA:O07086" /db_xref="InterPro:IPR000620" /db_xref="SubtiList:BG12289" /db_xref="UniProtKB/Swiss-Prot:O07086" /translation="MKKGQLFIGALTCLVASMSWGAMFPVADHALEFVDPFYFSFIRY GVVTIMLVILLLVREGKKSFHLEGKAKWIILFGVMAFTIYNVLIFLGQRLMGKSGIMT ASIAEALMPMLSIVILWGYKHVKPKKYTMISILIAFLGASMVITKGNISFFFSLGDHL FSILFIFIGVLGWVVYTMGGQIFREWSTLRYSTLTCLFGTAITGIMTAILTAQGYVSV PSIKVIAAIKYDFLFMITLPGIIALLSWNYGIKILSSINGILFINFVPITTLLIMVIK GYNITAFDIVGTLFVIIGLILNNIYQRKEDYKQVLQKEKTNLTIT*" gene complement(2586285..2587250) /gene="yrdR" /locus_tag="BSU_26620" /old_locus_tag="BSU26620" promotor_-35 2587288..2587291 /Source="Nicolas_upshift_promotors" /id="U2050" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.601398601398601" /psig="0.905094905094905" /xcortree=1788 /SigmaFactorBS="aaattacaatgagaaTTATaaaaagaagtaagcATCAAGTAA AATGAACAAAAgtgatgaaaaacatcattgataatgatactttaatgaaggggggatc t" /listShort="yrdQ, S999" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2587306..2587325 /Source="Nicolas_upshift_promotors" /id="U2050" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.601398601398601" /psig="0.905094905094905" /xcortree=1788 /SigmaFactorBS="aaattacaatgagaaTTATaaaaagaagtaagcATCAAGTAA AATGAACAAAAgtgatgaaaaacatcattgataatgatactttaatgaaggggggatc t" /listShort="yrdQ, S999" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2587333 /Source="Nicolas_upshifts" /id="U2050" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.601398601398601" /psig="0.905094905094905" /xcortree=1788 /SigmaFactorBS="aaattacaatgagaaTTATaaaaagaagtaagcATCAAGTAA AATGAACAAAAgtgatgaaaaacatcattgataatgatactttaatgaaggggggatc t" /listShort="yrdQ, S999" /GFF_Attribute="listLong" CDS 2587376..2588242 /gene="czcR" /locus_tag="BSU_26630" /old_locus_tag="BSU26630" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2b: Function from indirect experimental evidences (e.g. phenotypes); PubMedId: 22666466, 25437189; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator (LysR family)" /protein_id="NP_390540.1" /db_xref="EnsemblGenomes-Gn:BSU26630" /db_xref="EnsemblGenomes-Tr:CAB14604" /db_xref="GOA:P71025" /db_xref="InterPro:IPR000847" /db_xref="InterPro:IPR005119" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG12288" /db_xref="UniProtKB/Swiss-Prot:P71025" /translation="MELRDLQIFKCVAHHKSITGAAKELNYVQSNVTARIKQLENELK TPLFNRHKKGVSLSPEGRKMIEYVNKILKDVEELEQVFLDTEIPSGILKIGTVETVRI LPTIIASYYKKYPNVDLSLQAGLTEELIKKVMNHELDGAFISGPLKHSILEQYDVYTE KLTLVTSNKTFNIEDFSTTPILVFNQGCGYRSRLEQWLKDEGVLPNRMMEFNILETIL NSVALGLGITVVPESAVMHLAVQGKVYCHPLPEKDSCISTIFIRHKDAYLTNSMRSLL KTIVEHKNMSMA*" gene 2587376..2588242 /gene="czcR" /locus_tag="BSU_26630" /old_locus_tag="BSU26630" S_feature 2588243..2588343 /Source="Nicolas_S_feature" /locus_tag="new_2722645_2722745" /HighExp="HiTm, dia15, LBGstat, LPhT, T0.30H, Diami, Paraq, dia5, H2O2, Cold" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.905" /TUlongSig="NA" /TUlongPSig="NA" /label="S999" downshifts 2588301 /Source="Nicolas_upshifts" /id="D1364" /incds=0 /nref=6 /ntot=135 /MaxReadThrough="2.57006" /MaxDrop="3.43983" /score="-6.36950065" /energy="-7" /TU="NA" /idTUdmin="U2050" /TUdmin=0 /isTUend="TRUE" CDS complement(2588365..2589402) /gene="yrdP" /locus_tag="BSU_26640" /old_locus_tag="BSU26640" /EC_number="1.14.-.-" /function="16.8: Protect" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 9099864, 12100555, 12527699; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative oxidoreductase" /protein_id="NP_390541.1" /db_xref="EnsemblGenomes-Gn:BSU26640" /db_xref="EnsemblGenomes-Tr:CAB14605" /db_xref="GOA:O07085" /db_xref="InterPro:IPR000103" /db_xref="InterPro:IPR000960" /db_xref="InterPro:IPR036188" /db_xref="SubtiList:BG11980" /db_xref="UniProtKB/Swiss-Prot:O07085" /translation="MYDTIVIGAGQAGISIGYYLKQSDQKFIILDKSHEVGESWKDRY DSLVLFTSRMYSSLPGMHLEGEKHGFPSKNEIVAYLKKYVKKFEIPIQLRTEVISVLK IKNYFLIKTNREEYQTKNLVIATGPFHTPNIPSISKDLSDNINQLHSSQYKNSKQLAY GNVLVVGGGNSGAQIAVELSKERVTYLACSNKLVYFPLMIGKRSIFWWFDKLGVLHAS HTSIVGKFIQKKGDPVFGHELKHAIKQKEIILKKRVIAAKQNEIIFKDSSTLEVNNII WATGFRNPLCWINIKGVLDQEGRIIHHRGVSPVEGLYFIGLPWQHKRGSALLQGVGND AEYIVKQMNGE*" gene complement(2588365..2589402) /gene="yrdP" /locus_tag="BSU_26640" /old_locus_tag="BSU26640" downshifts complement(2588377) /Source="Nicolas_upshifts" /id="D1365" /incds=0 /nref=30 /ntot=134 /MaxReadThrough="2.50972" /MaxDrop="5.83595" /score="2.19797168" /energy="-12.5" /TU="NA" /idTUdmin="U2051" /TUdmin=0 /isTUend="TRUE" S_feature complement(2589403..2589489) /Source="Nicolas_S_feature" /locus_tag="new_2723805_2723891_c" /HighExp="LBGtran, dia5, Gly, Diami, LBGstat, M0t45, LBGexp, Lbtran, dia0, LoTm" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="0.907, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S1000" CDS complement(2589490..2590425) /gene="czcD" /locus_tag="BSU_26650" /old_locus_tag="BSU26650" /function="16.1: Circulate" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:10735849, 12100555, 15849754, 15948947, 16850406, 22447126, 26787764, 27210016" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10735849, 12100555, 15849754, 15948947, 16850406, 22447126, 26787764, 27210016; Product type t: transporter" /codon_start=1 /transl_table=11 /product="potassium/proton-divalent cation antiporter" /protein_id="NP_390542.1" /db_xref="EnsemblGenomes-Gn:BSU26650" /db_xref="EnsemblGenomes-Tr:CAB14606" /db_xref="GOA:O07084" /db_xref="InterPro:IPR002524" /db_xref="InterPro:IPR027469" /db_xref="InterPro:IPR027470" /db_xref="InterPro:IPR036837" /db_xref="SubtiList:BG11931" /db_xref="UniProtKB/Swiss-Prot:O07084" /translation="MGHNHNEGANKKVLLISFIMITGYMIIEAIGGFLTNSLALLSDA GHMLSDSISLMVALIAFTLAEKKANHNKTFGYKRFEILAAVINGAALILISLYIIYEA IERFSNPPKVATTGMLTISIIGLVVNLLVAWIMMSGGDTKNNLNIRGAYLHVISDMLG SVGAILAAILIIFFGWGWADPLASIIVAILVLRSGYNVTKDSIHILMEGTPENIDVSD IIRTIEGTEGIQNIHDLHIWSITSGLNALSCHAVVDDQLTISESENILRKIEHELEHK GITHVTIQMETEAHNHDNAILCQPKMEKQRDHHHH*" gene complement(2589490..2590425) /gene="czcD" /locus_tag="BSU_26650" /old_locus_tag="BSU26650" promotor_-10 complement(2590460..2590479) /Source="Nicolas_upshift_promotors" /id="U2051" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.809190809190809" /psig="0.907092907092907" /xcortree=1543 /SigmaFactorBS="ctcatatataaatattatttgtatcaTGTTAGAAtgcttcat aacagaTTTGAAATAATAAATACATAtgtattaaaaactttaggtaaggaggagtttt t" /listShort="czcD, S1000, yrdP" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2590467) /Source="Nicolas_upshifts" /id="U2051" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.809190809190809" /psig="0.907092907092907" /xcortree=1543 /SigmaFactorBS="ctcatatataaatattatttgtatcaTGTTAGAAtgcttcat aacagaTTTGAAATAATAAATACATAtgtattaaaaactttaggtaaggaggagtttt t" /listShort="czcD, S1000, yrdP" /GFF_Attribute="listLong" S_feature complement(2590469..2590552) /Source="Nicolas_S_feature" /locus_tag="new_2724871_2724954_c" /HighExp="dia5, Gly, LBGtran, Diami, LBGstat, LBGexp, LoTm, dia0, Lbexp, M0t45" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1001" promotor_-35 complement(2590494..2590501) /Source="Nicolas_upshift_promotors" /id="U2051" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.809190809190809" /psig="0.907092907092907" /xcortree=1543 /SigmaFactorBS="ctcatatataaatattatttgtatcaTGTTAGAAtgcttcat aacagaTTTGAAATAATAAATACATAtgtattaaaaactttaggtaaggaggagtttt t" /listShort="czcD, S1000, yrdP" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(2590533..2590552) /Source="Nicolas_upshift_promotors" /id="U2052" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.546453546453546" /psig=1 /xcortree=1541 /SigmaFactorBS="gaataattaaggaggtattgtggatttctataaaaatatTTT GACATttcagtaaagagcAGATATATTTATATATGAACacatgctcatatataaatat t" /listShort="S1001, czcD, S1000, yrdP" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2590552) /Source="Nicolas_upshifts" /id="U2052" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.546453546453546" /psig=1 /xcortree=1541 /SigmaFactorBS="gaataattaaggaggtattgtggatttctataaaaatatTTT GACATttcagtaaagagcAGATATATTTATATATGAACacatgctcatatataaatat t" /listShort="S1001, czcD, S1000, yrdP" /GFF_Attribute="listLong" promotor_-35 complement(2590566..2590573) /Source="Nicolas_upshift_promotors" /id="U2052" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.546453546453546" /psig=1 /xcortree=1541 /SigmaFactorBS="gaataattaaggaggtattgtggatttctataaaaatatTTT GACATttcagtaaagagcAGATATATTTATATATGAACacatgctcatatataaatat t" /listShort="S1001, czcD, S1000, yrdP" /GFF_Attribute="listLong" /label="promotor_-35" downshifts complement(2590687) /Source="Nicolas_upshifts" /id="D1366" /incds=0 /nref=1 /ntot=41 /MaxReadThrough="3.75163" /MaxDrop="3.57795" /score="38.5313506" /energy="-18.1" /TU="NA" /idTUdmin="U2051" /TUdmin="-2310" /isTUend="FALSE" CDS complement(2590712..2591101) /gene="yrdN" /locus_tag="BSU_26660" /old_locus_tag="BSU26660" /EC_number="5.3.2.-" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative tautomerase" /protein_id="NP_390543.1" /db_xref="EnsemblGenomes-Gn:BSU26660" /db_xref="EnsemblGenomes-Tr:CAB14607" /db_xref="GOA:P94502" /db_xref="InterPro:IPR004370" /db_xref="InterPro:IPR014347" /db_xref="SubtiList:BG12287" /db_xref="UniProtKB/Swiss-Prot:P94502" /translation="MPLLRFDLIEGRDQSSLKKLLDVAHNVVVEAFDVPQQDRYQIVH EHPENHMIIEDTGLGFNRTKNLVVLSVTSKSRPEEKKQKFYRLLAERLESECGIASTD LIVSIVENDNADWSFGLGEAQFLTGKL*" gene complement(2590712..2591101) /gene="yrdN" /locus_tag="BSU_26660" /old_locus_tag="BSU26660" promotor_-35 2591349..2591356 /Source="Nicolas_upshift_promotors" /id="U2053" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.525474525474525" /psig="0.998001998001998" /xcortree=2368 /SigmaFactorBS="ttagaaatcatttattcttctaagctttAGTTTACAtgaagc tctgctatcATATATAATTCAAAATTAAGatggaagacatctcaaaatcagatatcaa c" /listShort="gltR" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2591372..2591391 /Source="Nicolas_upshift_promotors" /id="U2053" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.525474525474525" /psig="0.998001998001998" /xcortree=2368 /SigmaFactorBS="ttagaaatcatttattcttctaagctttAGTTTACAtgaagc tctgctatcATATATAATTCAAAATTAAGatggaagacatctcaaaatcagatatcaa c" /listShort="gltR" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2591381 /Source="Nicolas_upshifts" /id="U2053" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.525474525474525" /psig="0.998001998001998" /xcortree=2368 /SigmaFactorBS="ttagaaatcatttattcttctaagctttAGTTTACAtgaagc tctgctatcATATATAATTCAAAATTAAGatggaagacatctcaaaatcagatatcaa c" /listShort="gltR" /GFF_Attribute="listLong" CDS 2591435..2592325 /gene="gltR" /locus_tag="BSU_26670" /old_locus_tag="BSU26670" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:9023181, 28294562" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9023181, 28294562; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator (LysR family)" /protein_id="NP_390544.2" /db_xref="EnsemblGenomes-Gn:BSU26670" /db_xref="EnsemblGenomes-Tr:CAB14608" /db_xref="GOA:P94501" /db_xref="InterPro:IPR000847" /db_xref="InterPro:IPR005119" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG11942" /db_xref="UniProtKB/Swiss-Prot:P94501" /translation="MNIQLLQVFLTTAREGSISKAALTLNYAQSNVTNKIQQLENDLQ TKLFYRHSRGITLTPPGQILVSYSEKILHTIEEARAAMGESSAPSGPLRIGSMETTAA VWLPQLLAHYNNLYPNVDLNLVTGPTEQQIQAVLHYELNGAFISGPIEHPDLVQEKVL DEEMVLVTSASHPVISSIQDVQTQTMLVFRKGCSYRAKLNHILQEEGLLPIKLMEFGI LEAIIGCVSAGLGISLLPRSIIASHEKEGRIRSHTISDKYSFVSTMFIRRKDTLITPA LSAFLTHMRDHFQIKRPDQS*" gene 2591435..2592325 /gene="gltR" /locus_tag="BSU_26670" /old_locus_tag="BSU26670" promotor_-35 2592013..2592018 /Source="Nicolas_upshift_promotors" /id="U2054" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1013 /SigmaFactorBS="acacaaacaatgcttgtattccgtaaaggatgCTCATAcaga gcaaagctcaaTCATATCCTGCAAGAAGAAggtttattacctataaaattaatggaat t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2592034..2592052 /Source="Nicolas_upshift_promotors" /id="U2054" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1013 /SigmaFactorBS="acacaaacaatgcttgtattccgtaaaggatgCTCATAcaga gcaaagctcaaTCATATCCTGCAAGAAGAAggtttattacctataaaattaatggaat t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2592041 /Source="Nicolas_upshifts" /id="U2054" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1013 /SigmaFactorBS="acacaaacaatgcttgtattccgtaaaggatgCTCATAcaga gcaaagctcaaTCATATCCTGCAAGAAGAAggtttattacctataaaattaatggaat t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" CDS complement(2592483..2592800) /gene="yrdK" /locus_tag="BSU_26680" /old_locus_tag="BSU26680" /function="18: Unknown function" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="NP_390545.3" /db_xref="EnsemblGenomes-Gn:BSU26680" /db_xref="EnsemblGenomes-Tr:CAB14609" /db_xref="SubtiList:BG12286" /db_xref="UniProtKB/Swiss-Prot:P94500" /translation="MRLYTEYIPNKNKLINQQQYHSDLQDLLHQWILQLLQLDVLPLS NRKYQSSRCHPKSVGEYLIVVRAIDALGNSQPLTSRRNQVSRAMTFVQNSLNEENLHP NID*" gene complement(2592483..2592800) /gene="yrdK" /locus_tag="BSU_26680" /old_locus_tag="BSU26680" CDS complement(2592758..2594080) /gene="brnQ" /locus_tag="BSU_26690" /old_locus_tag="BSU26690" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:8544834, 9287000, 9531631, 15849754, 16850406, 25645558" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8544834, 9287000, 9531631, 15849754, 16850406, 25645558; Product type t : transporter" /codon_start=1 /transl_table=11 /product="low-affinity branched-chain amino acid transporter" /protein_id="NP_390546.1" /db_xref="EnsemblGenomes-Gn:BSU26690" /db_xref="EnsemblGenomes-Tr:CAB14610" /db_xref="GOA:P94499" /db_xref="InterPro:IPR004685" /db_xref="SubtiList:BG11918" /db_xref="UniProtKB/Swiss-Prot:P94499" /translation="MSKKVSASYIIIIGLMLFALFFGAGNLIFPPMLGQLAGKNVWVA NAGFLVTGVGLPLLAITAFVFSGKQNLQSLASRVHPVFGIVFTTILYLAIGPFFAIPR SGNVSFEIGVKPFLSNDASPVSLIIFTILFFALACLLSLNPSKIIDIVGKFLTPIKLT FIGLLVAVALIRPIGTIQAPSKGYTSQAFFKGFQEGYLTLDALVAFVFGIIIVNALKE QGASTKKQLIVVCAKAAAIAAVLLAVMYTALSYMGASSVEELGILENGAEVLAKVSSY YFGSYGSILLGLMITVACLTTSVGLITACSSFFHELFPNISYKKIAVVLSVFSTLVAN IGLTQLIKVSMPVLLTMYPIAISLIFLTFLHSVFKGKTEVYQGSLLFAFIISLFDGLK AAGIKIEVVNRIFTQILPMYNIGLGWLIPAIAGGICGYILSIFRTKTS*" gene complement(2592758..2594080) /gene="brnQ" /locus_tag="BSU_26690" /old_locus_tag="BSU26690" CDS complement(2594245..2594577) /gene="azlD" /locus_tag="BSU_26700" /old_locus_tag="BSU26700" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:9287000, 25645558" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9287000, 25645558; Product type t: transporter" /codon_start=1 /transl_table=11 /product="branched-chain amino acid / methionine exporter" /protein_id="NP_390547.1" /db_xref="EnsemblGenomes-Gn:BSU26700" /db_xref="EnsemblGenomes-Tr:CAB14611" /db_xref="GOA:O07923" /db_xref="InterPro:IPR008407" /db_xref="SubtiList:BG11916" /db_xref="UniProtKB/Swiss-Prot:O07923" /translation="MTMTMTQQMITIAMVVLGTMLTRFLPFMIFPSGKPTPKYVQYLG KVLPSAVIGLLVIYCLKDVSLLSGSHGIPELVGAAAVVLLHLWKKNMLLSIAGGTVVY MVLVQLVF*" gene complement(2594245..2594577) /gene="azlD" /locus_tag="BSU_26700" /old_locus_tag="BSU26700" CDS complement(2594574..2595338) /gene="azlC" /locus_tag="BSU_26710" /old_locus_tag="BSU26710" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:9287000, 15849754, 16850406, 25645558" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9287000, 15849754, 16850406, 25645558; Product type t: transporter" /codon_start=1 /transl_table=11 /product="branched-chain amino acid / methionine exporter" /protein_id="NP_390548.1" /db_xref="EnsemblGenomes-Gn:BSU26710" /db_xref="EnsemblGenomes-Tr:CAB14612" /db_xref="GOA:O07942" /db_xref="InterPro:IPR004471" /db_xref="InterPro:IPR011606" /db_xref="SubtiList:BG11915" /db_xref="UniProtKB/Swiss-Prot:O07942" /translation="MNKNKESLHLSSPAINTHMNKRSQIWAAFRSAFPYTIPIFAGFL FLGIAYGIFMHSLGFSAIYPIIMSFMIFAGSMEFVAANFLLGAFNPMNALFLTLMVNA RHLFYGISMLDKYRGTGKKKLYLIFGMCDESFSINYTANVPANVDKGWFMFFVTLLNH LYWVAGAAIGGIFGSYVKFNTEGLDFVMTALFIVIFIEQWMKEKKHYSALTGLGLSVA SLILFGGNQFIIPAMLAILGVLTVLRKPLEKAEVSV*" gene complement(2594574..2595338) /gene="azlC" /locus_tag="BSU_26710" /old_locus_tag="BSU26710" CDS complement(2595351..2595824) /gene="azlB" /locus_tag="BSU_26720" /old_locus_tag="BSU26720" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:9023181, 9287000, 26473603" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9023181, 9287000, 26473603; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional repressor of the azlBCD operon" /protein_id="NP_390549.1" /db_xref="EnsemblGenomes-Gn:BSU26720" /db_xref="EnsemblGenomes-Tr:CAB14613" /db_xref="GOA:O07920" /db_xref="InterPro:IPR000485" /db_xref="InterPro:IPR011008" /db_xref="InterPro:IPR011991" /db_xref="InterPro:IPR019885" /db_xref="InterPro:IPR019887" /db_xref="InterPro:IPR019888" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG11914" /db_xref="UniProtKB/Swiss-Prot:O07920" /translation="MGIMLDETDKAILRDLQEDASISNLNLSKKIGLSPSACLARTKN LVEAGIIKKFTTIVDEKKLGIEVTALALINLSPLNRETIHSFLEDINKFPQVQECYTL TGSHDYMLKIVAKDMESYRNFIIDSLMQNPAISGVDTSIVMSTEKRTVSVPIDEM*" gene complement(2595351..2595824) /gene="azlB" /locus_tag="BSU_26720" /old_locus_tag="BSU26720" CDS complement(2596158..2596433) /gene="yrdF" /locus_tag="BSU_26730" /old_locus_tag="BSU26730" /function="16.8: Protect" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative ribonuclease inhibitor" /protein_id="NP_390550.1" /db_xref="EnsemblGenomes-Gn:BSU26730" /db_xref="EnsemblGenomes-Tr:CAB14614" /db_xref="GOA:O07938" /db_xref="InterPro:IPR000468" /db_xref="InterPro:IPR035905" /db_xref="SubtiList:BG12285" /db_xref="UniProtKB/Swiss-Prot:O07938" /translation="MRKIIIDGRDFENIEVLHDDLKDKLDFPDYYGRNLDALWDCLTG WVDLPLTLVLKNFEFSNTFLGSYADDVLEVIQEAQEELKDEFKIIIE*" gene complement(2596158..2596433) /gene="yrdF" /locus_tag="BSU_26730" /old_locus_tag="BSU26730" misc_feature complement(2596445..2596464) /Source="Nicolas_upshift_promotors" /id="U2055" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.881118881118881" /psig="0.972027972027972" /xcortree=3056 /SigmaFactorBS="ttttcagcctcatttggacaaacagctgttacatagtaaacg tttgtTAAGATAAAATAATGGAGGGcatagtttctaatgagaaaaataataatagatg g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(2596451) /Source="Nicolas_upshifts" /id="U2055" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.881118881118881" /psig="0.972027972027972" /xcortree=3056 /SigmaFactorBS="ttttcagcctcatttggacaaacagctgttacatagtaaacg tttgtTAAGATAAAATAATGGAGGGcatagtttctaatgagaaaaataataatagatg g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" S_feature complement(2596519..2596704) /Source="Nicolas_S_feature" /locus_tag="new_2730921_2731106_c" /HighExp="BT, S4, S8, S3, S5, S7, S6, LoTm, B36, G/S" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigEF" /TUshortPSig="0.977" /TUlongSig="NA" /TUlongPSig="NA" /label="S1002" CDS complement(2596705..2597937) /gene="cypA" /locus_tag="BSU_26740" /old_locus_tag="BSU26740" /EC_number="1.14.-.-" /function="16.8: Protect" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:9778370, 12354229, 28898812" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9778370, 12354229, 28898812; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="cytochrome P450" /protein_id="NP_390551.1" /db_xref="EnsemblGenomes-Gn:BSU26740" /db_xref="EnsemblGenomes-Tr:CAB14615" /db_xref="GOA:O08469" /db_xref="InterPro:IPR001128" /db_xref="InterPro:IPR002397" /db_xref="InterPro:IPR017972" /db_xref="InterPro:IPR036396" /db_xref="SubtiList:BG11929" /db_xref="UniProtKB/Swiss-Prot:O08469" /translation="MSSKEKKSVTILTESQLSSRAFKDEAYEFYKELRKSQALYPLSL GALGKGWLISRYDDAIHLLKNEKLKKNYENVFTAKEKRPALLKNEETLTKHMLNSDPP DHNRLRTLVQKAFTHRMILQLEDKIQHIADSLLDKVQPNKFMNLVDDYAFPLPIIVIS EMLGIPLEDRQKFRVWSQAIIDFSDAPERLQENDHLLGEFVEYLESLVRKKRREPAGD LISALIQAESEGTQLSTEELYSMIMLLIVAGHETTVNLITNMTYALMCHHDQLEKLRQ QPDLMNSAIEEALRFHSPVELTTIRWTAEPFILHGQEIKRKDVIIISLASANRDEKIF PNADIFDIERKNNRHIAFGHGNHFCLGAQLARLEAKIAISTLLRRCPNIQLKGEKKQM KWKGNFLMRALEELPISF*" gene complement(2596705..2597937) /gene="cypA" /locus_tag="BSU_26740" /old_locus_tag="BSU26740" CDS complement(2597987..2598145) /gene="yrdDc" /locus_tag="BSU_26748" /old_locus_tag="BSU26748" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /pseudo /codon_start=1 /transl_table=11 /product="hypothetical protein; C-terminal part of YrdD" /db_xref="PSEUDO:CAX52669.1" /translation="MEVLGVSPFYQGKSLGSKMINDCLISFISKCGDGILALIMNTDL NGSFYKSS*" gene complement(2597987..2598145) /gene="yrdDc" /locus_tag="BSU_26748" /old_locus_tag="BSU26748" /pseudo CDS complement(2598142..2598345) /gene="yrdDm" /locus_tag="BSU_26749" /old_locus_tag="BSU26749" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /pseudo /codon_start=1 /transl_table=11 /product="hypothetical protein; internal part of YrdD" /db_xref="SubtiList:BG12284" /translation="MHKVLTRAYFKKHFFFVGIQNGEMVVAALLKHRDKPDIKLDRLY SSRGDNINQNGAKKFSKSLKEPA*" gene complement(2598142..2598345) /gene="yrdDm" /locus_tag="BSU_26749" /old_locus_tag="BSU26749" /pseudo promotor_-10 complement(2598306..2598324) /Source="Nicolas_upshift_promotors" /id="U2056" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.977022977022977" /psig="0.977022977022977" /xcortree=1116 /SigmaFactorBS="gtaaaacgcgaaaaaaagatcattcatttatttttgaaaTGC ATAaagtactgacaagaGCATATTTTAAAAAGCATTtcttttttgttggcattcagaa t" /listShort="yrdD, yrdD, cypA, S1002" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2598323) /Source="Nicolas_upshifts" /id="U2056" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.977022977022977" /psig="0.977022977022977" /xcortree=1116 /SigmaFactorBS="gtaaaacgcgaaaaaaagatcattcatttatttttgaaaTGC ATAaagtactgacaagaGCATATTTTAAAAAGCATTtcttttttgttggcattcagaa t" /listShort="yrdD, yrdD, cypA, S1002" /GFF_Attribute="listLong" CDS complement(2598330..2598479) /gene="yrdDn" /locus_tag="BSU_26750" /old_locus_tag="BSU26750" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /pseudo /codon_start=1 /transl_table=11 /product="hypothetical protein; N-terminal part of YrdD" /db_xref="SubtiList:BG14036" /translation="MFLYRQARADEVSKVAKLFHQSFNQYPFMDLLVKREKKIIHLFL KCIKY*" gene complement(2598330..2598479) /gene="yrdDn" /locus_tag="BSU_26750" /old_locus_tag="BSU26750" /pseudo promotor_-35 complement(2598339..2598344) /Source="Nicolas_upshift_promotors" /id="U2056" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.977022977022977" /psig="0.977022977022977" /xcortree=1116 /SigmaFactorBS="gtaaaacgcgaaaaaaagatcattcatttatttttgaaaTGC ATAaagtactgacaagaGCATATTTTAAAAAGCATTtcttttttgttggcattcagaa t" /listShort="yrdD, yrdD, cypA, S1002" /GFF_Attribute="listLong" /label="promotor_-35" downshifts complement(2598563) /Source="Nicolas_upshifts" /id="D1367" /incds=0 /nref=140 /ntot=216 /MaxReadThrough="2.2276" /MaxDrop="4.5127" /score="5.01317133" /energy="-16.7" /TU="NA" /idTUdmin="U2057" /TUdmin=0 /isTUend="TRUE" CDS complement(2598578..2599141) /gene="yrdC" /locus_tag="BSU_26760" /old_locus_tag="BSU26760" /EC_number="3.-.-.-" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative hydrolase" /protein_id="NP_390553.1" /db_xref="EnsemblGenomes-Gn:BSU26760" /db_xref="EnsemblGenomes-Tr:CAB14617" /db_xref="GOA:O07081" /db_xref="InterPro:IPR000868" /db_xref="InterPro:IPR036380" /db_xref="SubtiList:BG12283" /db_xref="UniProtKB/Swiss-Prot:O07081" /translation="MEEKKALIIVDVQKAFDDKKWGERNNVKAEENISKILELWREKG WTVIYIQHTSDKPHSLFHPKNEGFAIKEIVKPMDEEVIITKTVNSSFIGTNLEEFLKL NEITTVVITGLTTPHCVSTTTRMSGNLGFDTYLISDATAAFGMRDQNDTYYDAATIHN ISLATLHDEFATILTTDQLINDFIKTH*" gene complement(2598578..2599141) /gene="yrdC" /locus_tag="BSU_26760" /old_locus_tag="BSU26760" downshifts 2599059 /Source="Nicolas_upshifts" /id="D1368" /incds=1 /nref=44 /ntot=194 /MaxReadThrough="1.72227" /MaxDrop="3.37915" /score="14.6499034" /energy="-6.6" /TU="NA" /idTUdmin="U2060" /TUdmin="-4488" /isTUend="FALSE" promotor_-10 complement(2599171..2599190) /Source="Nicolas_upshift_promotors" /id="U2057" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.856143856143856" /psig="0.997002997002997" /xcortree=2342 /SigmaFactorBS="ggcgctcatttgaaattcatcattaaaCAATTGTAcaaaagt aaaatttGTATTTAGAATGTAGTAATAaatagaaattctacgtaggagggtatcttgt g" /listShort="yrdC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2599179) /Source="Nicolas_upshifts" /id="U2057" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.856143856143856" /psig="0.997002997002997" /xcortree=2342 /SigmaFactorBS="ggcgctcatttgaaattcatcattaaaCAATTGTAcaaaagt aaaatttGTATTTAGAATGTAGTAATAaatagaaattctacgtaggagggtatcttgt g" /listShort="yrdC" /GFF_Attribute="listLong" promotor_-35 complement(2599205..2599212) /Source="Nicolas_upshift_promotors" /id="U2057" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.856143856143856" /psig="0.997002997002997" /xcortree=2342 /SigmaFactorBS="ggcgctcatttgaaattcatcattaaaCAATTGTAcaaaagt aaaatttGTATTTAGAATGTAGTAATAaatagaaattctacgtaggagggtatcttgt g" /listShort="yrdC" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2599370..2599741) /gene="yrdB" /locus_tag="BSU_26770" /old_locus_tag="BSU26770" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative integral inner membrane protein" /protein_id="NP_390554.1" /db_xref="EnsemblGenomes-Gn:BSU26770" /db_xref="EnsemblGenomes-Tr:CAB14618" /db_xref="GOA:O07080" /db_xref="InterPro:IPR021214" /db_xref="SubtiList:BG12282" /db_xref="UniProtKB/Swiss-Prot:O07080" /translation="MEKLNQTNLLLRFTLEIAALISLGVYAWISFNGYFKYVLTLVLP IAVMIVWSVFAVPHDPSRSGQTVIAVNGVTRLVIELLIFAMAVAALYFSYLKPVSIVF LCLIILHYIISAERIKWLLNQ*" gene complement(2599370..2599741) /gene="yrdB" /locus_tag="BSU_26770" /old_locus_tag="BSU26770" S_feature complement(2599742..2599971) /Source="Nicolas_S_feature" /locus_tag="new_2734144_2734373_c" /HighExp="BMM, GM 120, GM 90, SMM, MG 150, GM 60, MG 120, M9-tran, Glu, S1" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.48162700000000003" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1003" promotor_-10 complement(2599953..2599972) /Source="Nicolas_upshift_promotors" /id="U2058" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.992007992007992" /psig=1 /xcortree=3041 /SigmaFactorBS="gtataatctttacttcgttcgacaaattctgcaaatTGTAGA CAacttcctgattatTTGGATAATTAACTGAATAGgaggggaaaagttgtcatatttc a" /listShort="S1003, yrdB" /listLong="yrdC" /label="promotor_-10" upshifts complement(2599969) /Source="Nicolas_upshifts" /id="U2058" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.992007992007992" /psig=1 /xcortree=3041 /SigmaFactorBS="gtataatctttacttcgttcgacaaattctgcaaatTGTAGA CAacttcctgattatTTGGATAATTAACTGAATAGgaggggaaaagttgtcatatttc a" /listShort="S1003, yrdB" /listLong="yrdC" promotor_-35 complement(2599986..2599993) /Source="Nicolas_upshift_promotors" /id="U2058" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.992007992007992" /psig=1 /xcortree=3041 /SigmaFactorBS="gtataatctttacttcgttcgacaaattctgcaaatTGTAGA CAacttcctgattatTTGGATAATTAACTGAATAGgaggggaaaagttgtcatatttc a" /listShort="S1003, yrdB" /listLong="yrdC" /label="promotor_-35" downshifts complement(2600537) /Source="Nicolas_upshifts" /id="D1369" /incds=0 /nref=174 /ntot=248 /MaxReadThrough="2.42722" /MaxDrop="5.81863" /score="7.90390368" /energy="-10.3" /TU="NA" /idTUdmin="U2059" /TUdmin=6 /isTUend="TRUE" CDS complement(2600551..2601054) /gene="yrdA" /locus_tag="BSU_26780" /old_locus_tag="BSU26780" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 22720735" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_390555.1" /db_xref="EnsemblGenomes-Gn:BSU26780" /db_xref="EnsemblGenomes-Tr:CAB14619" /db_xref="GOA:O07079" /db_xref="InterPro:IPR007837" /db_xref="InterPro:IPR034660" /db_xref="SubtiList:BG12281" /db_xref="UniProtKB/Swiss-Prot:O07079" /translation="MFQTLDHFLKSWEFEADATQKLLNSLTDESLKQEITSQNWTLGR IAWHTVAAIGIITSNTDLTFQAPAEDYPVPTSAQFIADSYHQASNAFVQALKTQWTDH TLQERINFIGQQMPNGSLLMFLIQHQNHHRGQMTVLMRQAGLTVPGIYGPAKEEWAKF GLEAPKM*" gene complement(2600551..2601054) /gene="yrdA" /locus_tag="BSU_26780" /old_locus_tag="BSU26780" S_feature complement(2601055..2601279) /Source="Nicolas_S_feature" /locus_tag="new_2735457_2735681_c" /HighExp="Etha, Lbstat, M0t90, M40t90, LoTm, M9-stat, Gly, S2, T0.30H, T4.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.997" /TUlongSig="NA" /TUlongPSig="NA" /label="S1004" CDS complement(2601280..2602134) /gene="aadK" /locus_tag="BSU_26790" /old_locus_tag="BSU26790" /EC_number="2.7.7.-" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:8293959" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8293959; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="aminoglycoside 6-adenylyltransferase" /protein_id="NP_390556.1" /db_xref="EnsemblGenomes-Gn:BSU26790" /db_xref="EnsemblGenomes-Tr:CAB14620" /db_xref="GOA:P17585" /db_xref="InterPro:IPR007530" /db_xref="PDB:2PBE" /db_xref="SubtiList:BG11037" /db_xref="UniProtKB/Swiss-Prot:P17585" /translation="MRSEQEMMDIFLDFALNDERIRLVTLEGSRTNRNIPPDNFQDYD ISYFVTDVESFKENDQWLEIFGKRIMMQKPEDMELFPPELGNWFSYIILFEDGNKLDL TLIPIREAEDYFANNDGLVKVLLDKDSFINYKVTPNDRQYWIKRPTAREFDDCCNEFW MVSTYVVKGLARNEILFAIDHLNEIVRPNLLRMMAWHIASQKGYSFSMGKNYKFMKRY LSNKEWEELMSTYSVNGYQEMWKSLFTCYALFRKYSKAVSEGLAYKYPDYDEGITKYT EGIYCSVK*" gene complement(2601280..2602134) /gene="aadK" /locus_tag="BSU_26790" /old_locus_tag="BSU26790" S_feature complement(2602135..2602237) /Source="Nicolas_S_feature" /locus_tag="new_2736537_2736639_c" /HighExp="M9-stat, T3.0H, T0.30H, T1.30H, T2.30H, Lbtran, T3.30H, T1.0H, M0t90, Lbstat" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.997" /TUlongSig="NA" /TUlongPSig="NA" /label="S1005" promotor_-10 complement(2602218..2602237) /Source="Nicolas_upshift_promotors" /id="U2059" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.909090909090909" /psig="0.997002997002997" /xcortree=3219 /SigmaFactorBS="gttgatatctgattttgagatgtcttgcatcttaatattgAA TGatatataggagaacATCATGTAAAATAAAGCTTAgaagaatacatcacattcaaga g" /listShort="S1005, aadK, S1004, yrdA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2602235) /Source="Nicolas_upshifts" /id="U2059" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.909090909090909" /psig="0.997002997002997" /xcortree=3219 /SigmaFactorBS="gttgatatctgattttgagatgtcttgcatcttaatattgAA TGatatataggagaacATCATGTAAAATAAAGCTTAgaagaatacatcacattcaaga g" /listShort="S1005, aadK, S1004, yrdA" /GFF_Attribute="listLong" promotor_-35 complement(2602252..2602255) /Source="Nicolas_upshift_promotors" /id="U2059" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.909090909090909" /psig="0.997002997002997" /xcortree=3219 /SigmaFactorBS="gttgatatctgattttgagatgtcttgcatcttaatattgAA TGatatataggagaacATCATGTAAAATAAAGCTTAgaagaatacatcacattcaaga g" /listShort="S1005, aadK, S1004, yrdA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 2602406..2602413 /Source="Nicolas_upshift_promotors" /id="U2060" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.723276723276723" /psig="0.894105894105894" /xcortree=2930 /SigmaFactorBS="atcgacatgttaactggtatgagaGATTGACAaaaagaagga aaaCGATATATTTAAGCGAATACgagtttttgagtaaattttaaaatgacactttttt c" /listShort="S1006, yrpB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2602427..2602446 /Source="Nicolas_upshift_promotors" /id="U2060" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.723276723276723" /psig="0.894105894105894" /xcortree=2930 /SigmaFactorBS="atcgacatgttaactggtatgagaGATTGACAaaaagaagga aaaCGATATATTTAAGCGAATACgagtttttgagtaaattttaaaatgacactttttt c" /listShort="S1006, yrpB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2602442 /Source="Nicolas_upshifts" /id="U2060" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.723276723276723" /psig="0.894105894105894" /xcortree=2930 /SigmaFactorBS="atcgacatgttaactggtatgagaGATTGACAaaaagaagga aaaCGATATATTTAAGCGAATACgagtttttgagtaaattttaaaatgacactttttt c" /listShort="S1006, yrpB" /GFF_Attribute="listLong" S_feature 2602447..2602512 /Source="Nicolas_S_feature" /locus_tag="new_2736849_2736914" /HighExp="LoTm, BC, S1, S2, C90, T4.0H, HiOs, T5.0H, T3.30H, SMMPr" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.894" /TUlongSig="NA" /TUlongPSig="NA" /label="S1006" CDS 2602513..2603556 /gene="yrpB" /locus_tag="BSU_26800" /old_locus_tag="BSU26800" /EC_number="1.13.12.-" /function="16.8: Protect" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 9501443; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative anionic nitroalkane monoxygenase" /protein_id="NP_390557.1" /db_xref="EnsemblGenomes-Gn:BSU26800" /db_xref="EnsemblGenomes-Tr:CAB14621" /db_xref="GOA:O05413" /db_xref="InterPro:IPR004136" /db_xref="InterPro:IPR013785" /db_xref="SubtiList:BG12305" /db_xref="UniProtKB/Swiss-Prot:O05413" /translation="MNEFMKKFSLTKPIIQAPMAGGITKPRLASAVSNQGALGSLASG YLTPDLLEQQIKEIFELTDAPFQINVFVPLGLEMPPKDQIKKWKENIPLANQVNQFTS VQEEWDDFYQKIDLILKYKVKACSFTFDLPPEDAVKELKTAGCCLIGTASTVEEALLM EERGMDIVVLQGSEAGGHRGAFLPSKGESAVGLMALIPQAADALSVPVIAAGGMIDHR GVKAALTLGAQGVQIGSAFLICHESNAHPVHKQKILEANEADTKLTTLFSGKEARGIV NKWMEENEQFETQTLPYPYQNTLTKAMRQKASLQNNHDQMSLWAGQGIRSLTEEISVK QLLNQLCQEDIKI*" gene 2602513..2603556 /gene="yrpB" /locus_tag="BSU_26800" /old_locus_tag="BSU26800" downshifts 2603554 /Source="Nicolas_upshifts" /id="D1370" /incds=0 /nref=22 /ntot=198 /MaxReadThrough="1.3622" /MaxDrop="5.04821" /score="14.6499034" /energy="-6.6" /TU="NA" /idTUdmin="U2060" /TUdmin=7 /isTUend="TRUE" promotor_-35 2603841..2603848 /Source="Nicolas_upshift_promotors" /id="U2061" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.95904095904096" /psig=1 /xcortree=2015 /SigmaFactorBS="atcgatagctcccatattaaatttgaatagtaaaatggttct ttttCGTTTGATtcagatgatataaAGTCATATGATAAAAAAAGAatgagacagaaag c" /listShort="yrpC" /listLong="yrpD, S1007" /label="promotor_-35" upshifts 2603855 /Source="Nicolas_upshifts" /id="U2061" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.95904095904096" /psig=1 /xcortree=2015 /SigmaFactorBS="atcgatagctcccatattaaatttgaatagtaaaatggttct ttttCGTTTGATtcagatgatataaAGTCATATGATAAAAAAAGAatgagacagaaag c" /listShort="yrpC" /listLong="yrpD, S1007" promotor_-10 2603862..2603881 /Source="Nicolas_upshift_promotors" /id="U2061" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.95904095904096" /psig=1 /xcortree=2015 /SigmaFactorBS="atcgatagctcccatattaaatttgaatagtaaaatggttct ttttCGTTTGATtcagatgatataaAGTCATATGATAAAAAAAGAatgagacagaaag c" /listShort="yrpC" /listLong="yrpD, S1007" /label="promotor_-10" CDS 2603906..2604703 /gene="murI" /locus_tag="BSU_26810" /old_locus_tag="BSU26810" /EC_number="5.1.1.3" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:12829290, 15212785, 15347750, 17720142, 25777674" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12829290, 15212785, 15347750, 17720142, 25777674; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="glutamate racemase" /protein_id="NP_390558.1" /db_xref="EnsemblGenomes-Gn:BSU26810" /db_xref="EnsemblGenomes-Tr:CAB14622" /db_xref="GOA:O05412" /db_xref="InterPro:IPR001920" /db_xref="InterPro:IPR004391" /db_xref="InterPro:IPR015942" /db_xref="InterPro:IPR018187" /db_xref="SubtiList:BG12306" /db_xref="UniProtKB/Swiss-Prot:O05412" /translation="MKIGFFDSGIGGMTVLYEAIKVLPYEDYIFYADTLNVPYGEKSK GKVKEYIFNAAEFLASQNIKALVIACNTATSIAIEDLRRNFDFPIIGIEPAVKPAINK CTEERKRVLVVATNLTLKEEKFHNLVKEIDHHDLVDCLALPGLVEFAENFDFSEDKII KYLKNELSSFDLKQYGTIVLGCTHFPFFKNSFEKLFGIKVDMISGSVGTAKQLKKVLA DRNQLGKGSGSITFFNSGHKIVDQEVISKYKRLFEILDETQRSHVGH*" gene 2603906..2604703 /gene="murI" /locus_tag="BSU_26810" /old_locus_tag="BSU26810" promotor_-35 2605009..2605013 /Source="Nicolas_upshift_promotors" /id="U2062" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.304695304695305" /psig="0.997002997002997" /xcortree=3238 /SigmaFactorBS="gtgtaaattctgtatctatgtgcatgtttattATGGAattat tttcataaTGTTTTATAATACAAGATGAtagcgttttctaattataatgataggggga a" /listShort="yrpD, S1007, S1008, S1009, S1010" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2605027..2605046 /Source="Nicolas_upshift_promotors" /id="U2062" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.304695304695305" /psig="0.997002997002997" /xcortree=3238 /SigmaFactorBS="gtgtaaattctgtatctatgtgcatgtttattATGGAattat tttcataaTGTTTTATAATACAAGATGAtagcgttttctaattataatgataggggga a" /listShort="yrpD, S1007, S1008, S1009, S1010" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2605037 /Source="Nicolas_upshifts" /id="U2062" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.304695304695305" /psig="0.997002997002997" /xcortree=3238 /SigmaFactorBS="gtgtaaattctgtatctatgtgcatgtttattATGGAattat tttcataaTGTTTTATAATACAAGATGAtagcgttttctaattataatgataggggga a" /listShort="yrpD, S1007, S1008, S1009, S1010" /GFF_Attribute="listLong" promotor_-10 complement(2605061..2605075) /Source="Nicolas_upshift_promotors" /id="U2063" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.921078921078921" /psig="0.070929070929071" /xcortree=302 /SigmaFactorBS="caaaaagcacggttgccgtaagcgcacccgcaagcagacctt ttttcATCATcattatttCCCCCTATCATTATAattagaaaacgctatcatcttgtat t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2605075) /Source="Nicolas_upshifts" /id="U2063" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.921078921078921" /psig="0.070929070929071" /xcortree=302 /SigmaFactorBS="caaaaagcacggttgccgtaagcgcacccgcaagcagacctt ttttcATCATcattatttCCCCCTATCATTATAattagaaaacgctatcatcttgtat t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(2605084..2605088) /Source="Nicolas_upshift_promotors" /id="U2063" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.921078921078921" /psig="0.070929070929071" /xcortree=302 /SigmaFactorBS="caaaaagcacggttgccgtaagcgcacccgcaagcagacctt ttttcATCATcattatttCCCCCTATCATTATAattagaaaacgctatcatcttgtat t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" CDS 2605084..2605791 /gene="yrpD" /locus_tag="BSU_26820" /old_locus_tag="BSU26820" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 25355936; Product type lp: lipoprotein" /codon_start=1 /transl_table=11 /product="putative lipoprotein" /protein_id="NP_390559.1" /db_xref="EnsemblGenomes-Gn:BSU26820" /db_xref="EnsemblGenomes-Tr:CAB14623" /db_xref="InterPro:IPR029143" /db_xref="SubtiList:BG12307" /db_xref="UniProtKB/Swiss-Prot:O05411" /translation="MMKKGLLAGALTATVLFGTCAVDVPGIISPKTAEAASQLTDGIG GRAYLNSNGAILVTKIQLPSSTQVSNGTAYIYSGFSGGTESDIGFQYSDKYNVWKPYM KVGSKGQDQVQYLEGGSQFTNTKGFRPGSTVQLTIYKNLNGNTRATYWGTNNAGYNGR LISEISKTNVGSISKWKALATVATTGSRQSIKSNFSTSFTNITIDNKAITPVIDTQDF AKVTVSGNSVSLSVVKN*" gene 2605084..2605791 /gene="yrpD" /locus_tag="BSU_26820" /old_locus_tag="BSU26820" downshifts 2605791 /Source="Nicolas_upshifts" /id="D1371" /incds=0 /nref=4 /ntot=168 /MaxReadThrough="5.98921" /MaxDrop="2.677" /score="15.7112026" /energy="-8.2" /TU="U2062" /idTUdmin="U2064" /TUdmin="-660" /isTUend="FALSE" S_feature 2605836..2606009 /Source="Nicolas_S_feature" /locus_tag="new_2740238_2740411" /HighExp="Lbstat, M0t90, M40t90, BT, S0, ferm, S2, M9-stat, Lbtran, T1.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.997" /TUlongSig="SigA" /TUlongPSig=1 /label="S1007" promotor_-35 2605991..2605992 /Source="Nicolas_upshift_promotors" /id="U2064" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.591408591408591" /psig="0.861138861138861" /xcortree=1974 /SigmaFactorBS="ccccttctgaacctgttccatttgctcaacgcaaaaggtgTG catcactgtcttaaaAATGTTAAAACAAATAGCAGatggtgcactttatttttagatg a" /listShort="S1008, S1009" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2606008..2606027 /Source="Nicolas_upshift_promotors" /id="U2064" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.591408591408591" /psig="0.861138861138861" /xcortree=1974 /SigmaFactorBS="ccccttctgaacctgttccatttgctcaacgcaaaaggtgTG catcactgtcttaaaAATGTTAAAACAAATAGCAGatggtgcactttatttttagatg a" /listShort="S1008, S1009" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 2606011..2606339 /Source="Nicolas_S_feature" /locus_tag="new_2740413_2740741" /HighExp="Lbstat, M0t90, BT, M40t90, S2, S0, ferm, T2.0H, M9-stat, dia15" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.99711000000000005" /TUshortSig="SigA, SigA" /TUshortPSig="0.861, 0.997" /TUlongSig="NA" /TUlongPSig="NA" /label="S1008" upshifts 2606011 /Source="Nicolas_upshifts" /id="U2064" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.591408591408591" /psig="0.861138861138861" /xcortree=1974 /SigmaFactorBS="ccccttctgaacctgttccatttgctcaacgcaaaaggtgTG catcactgtcttaaaAATGTTAAAACAAATAGCAGatggtgcactttatttttagatg a" /listShort="S1008, S1009" /GFF_Attribute="listLong" CDS 2606115..2606276 /locus_tag="BSU_26829" /old_locus_tag="BSU26829" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /pseudo /codon_start=1 /transl_table=11 /product="hypothetical protein" /db_xref="PSEUDO:SOX90581.1" /translation="MYFHKRGMASYSSIASGRLANDWPRTTHHFETDSFQNHKYDPIT NKDQLAVQP*" gene 2606115..2606276 /locus_tag="BSU_26829" /old_locus_tag="BSU26829" /pseudo promotor_-35 2606305..2606314 /Source="Nicolas_upshift_promotors" /id="U2065" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1413 /SigmaFactorBS="atttttacatcaattaaactagcaTCACTATCGAataagctc gatcTGCATATCATGTACTATCCTcttttaaggaaggtgatgttatgaggtcatttcc a" /listShort="S1009, S1010" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2606327..2606346 /Source="Nicolas_upshift_promotors" /id="U2065" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1413 /SigmaFactorBS="atttttacatcaattaaactagcaTCACTATCGAataagctc gatcTGCATATCATGTACTATCCTcttttaaggaaggtgatgttatgaggtcatttcc a" /listShort="S1009, S1010" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 2606341..2606492 /Source="Nicolas_S_feature" /locus_tag="new_2740743_2740894" /HighExp="BT, S8, B36, S7, Lbstat, G/S, Pyr, M0t90, B60, M40t90" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.94474599999999997" /TUshortSig="SigK, SigA, SigA" /TUshortPSig="1, 0.861, 0.997" /TUlongSig="NA" /TUlongPSig="NA" /label="S1009" upshifts 2606341 /Source="Nicolas_upshifts" /id="U2065" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1413 /SigmaFactorBS="atttttacatcaattaaactagcaTCACTATCGAataagctc gatcTGCATATCATGTACTATCCTcttttaaggaaggtgatgttatgaggtcatttcc a" /listShort="S1009, S1010" /GFF_Attribute="listLong" CDS 2606367..2606444 /gene="yrpDX" /locus_tag="BSU_26826" /old_locus_tag="BSU26826" /experiment="publication(s) with functional evidences, PMID:20709900" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 20709900" /codon_start=1 /transl_table=11 /product="expressed polypeptide of unknown function" /protein_id="YP_009513985.1" /db_xref="EnsemblGenomes-Gn:BSU26826" /db_xref="EnsemblGenomes-Tr:CCQ48602" /db_xref="GOA:L8E9J8" /db_xref="InterPro:IPR010070" /db_xref="UniProtKB/TrEMBL:L8E9J8" /translation="MRSFPLIVVLFILLIIVGTSFFGGY*" gene 2606367..2606444 /gene="yrpDX" /locus_tag="BSU_26826" /old_locus_tag="BSU26826" downshifts 2606449 /Source="Nicolas_upshifts" /id="D1372" /incds=0 /nref=23 /ntot=198 /MaxReadThrough="3.86249" /MaxDrop="4.0885" /score="28.4802594" /energy="-18.1" /TU="U2062,U2065" /idTUdmin="U2064" /TUdmin="-2" /isTUend="TRUE" S_feature 2606494..2606691 /Source="Nicolas_S_feature" /locus_tag="new_2740896_2741093" /HighExp="BT, B36, S8, Lbstat, G/S, Pyr, Diami, S7, dia15, M0t90" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigK, SigA" /TUshortPSig="1, 0.997" /TUlongSig="NA" /TUlongPSig="NA" /label="S1010" S_feature complement(2606683..2606954) /Source="Nicolas_S_feature" /locus_tag="new_2741085_2741356_c" /HighExp="Heat, BMM, Etha, S2, S3, S4, B36, S5, B60, T0.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.40965600000000002" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1011" downshifts complement(2606725) /Source="Nicolas_upshifts" /id="D1373" /incds=0 /nref=37 /ntot=78 /MaxReadThrough="2.30607" /MaxDrop="6.9537" /score="19.9821634" /energy="-15.5" /TU="NA" /idTUdmin="U2066" /TUdmin=0 /isTUend="TRUE" CDS complement(2606731..2606892) /locus_tag="BSU_26827" /old_locus_tag="BSU26827" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_009513986.1" /translation="MGKKLIETIQYPPYYCDVAYLESSHMKSRRNLFQNKKSLDVWQW ITLEIYWLI*" gene complement(2606731..2606892) /locus_tag="BSU_26827" /old_locus_tag="BSU26827" CDS complement(2606955..2607710) /gene="zinT" /locus_tag="BSU_26830" /old_locus_tag="BSU26830" /function="16.14: Store" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 12904577, 24128931; Product type lp: lipoprotein" /codon_start=1 /transl_table=11 /product="lipoprotein buffering protein for Zn2+ transport" /protein_id="NP_390560.1" /db_xref="EnsemblGenomes-Gn:BSU26830" /db_xref="EnsemblGenomes-Tr:CAB14624" /db_xref="GOA:O05410" /db_xref="InterPro:IPR012674" /db_xref="InterPro:IPR015304" /db_xref="SubtiList:BG12308" /db_xref="UniProtKB/Swiss-Prot:O05410" /translation="MNILFSKRLGILTIGSLLVLAGCQTSGSSAGESNQTTSSSAVEE DSSKTQEQTSDSHTHEHSHDHSHAHDEETEKIYEGYFKNSQVKDRLLSDWEGDWQSVY PYLQDGTLDEVFSYKSEHEGGKTAEEYKEYYKKGYQTDVDRIVIQKDTVTFFKNGKEY SGKYTYDGYEILTYDAGNRGVRYIFKLAKKAEGLPQYIQFSDHSIYPTKASHYHLYWG DDREALLDEVKNWPTYYPSKMDGHDIAHEMMAH*" gene complement(2606955..2607710) /gene="zinT" /locus_tag="BSU_26830" /old_locus_tag="BSU26830" promotor_-10 complement(2607741..2607760) /Source="Nicolas_upshift_promotors" /id="U2066" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.54045954045954" /psig=1 /xcortree=666 /SigmaFactorBS="tttaaaataggccatccgcatgaagagcatttttccTTTGAT gtttgcaagagatgtATGTATAATAAATCGTAATGttttcgatttaataaaaaaggag t" /listShort="yrpE, S1011" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2607757) /Source="Nicolas_upshifts" /id="U2066" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.54045954045954" /psig=1 /xcortree=666 /SigmaFactorBS="tttaaaataggccatccgcatgaagagcatttttccTTTGAT gtttgcaagagatgtATGTATAATAAATCGTAATGttttcgatttaataaaaaaggag t" /listShort="yrpE, S1011" /GFF_Attribute="listLong" promotor_-35 complement(2607776..2607781) /Source="Nicolas_upshift_promotors" /id="U2066" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.54045954045954" /psig=1 /xcortree=666 /SigmaFactorBS="tttaaaataggccatccgcatgaagagcatttttccTTTGAT gtttgcaagagatgtATGTATAATAAATCGTAATGttttcgatttaataaaaaaggag t" /listShort="yrpE, S1011" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2607842..2608372) /gene="sigZ" /locus_tag="BSU_26840" /old_locus_tag="BSU26840" /function="16.3: Control" /function="16.12: Sense" /experiment="publication(s) with functional evidences, PMID:11700344, 15019740, 17675383" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11700344, 15019740, 17675383; Product type r: regulator" /codon_start=1 /transl_table=11 /product="RNA polymerase ECF(extracytoplasmic function)-type sigma factor (sigma-Z)" /protein_id="NP_390561.1" /db_xref="EnsemblGenomes-Gn:BSU26840" /db_xref="EnsemblGenomes-Tr:CAB14625" /db_xref="GOA:O05409" /db_xref="InterPro:IPR000838" /db_xref="InterPro:IPR007627" /db_xref="InterPro:IPR013249" /db_xref="InterPro:IPR013324" /db_xref="InterPro:IPR013325" /db_xref="InterPro:IPR014284" /db_xref="InterPro:IPR014304" /db_xref="InterPro:IPR036388" /db_xref="SubtiList:BG11976" /db_xref="UniProtKB/Swiss-Prot:O05409" /translation="MNIEDLWDQFHQPLKTYISHRVNDQSIVDDLLQIVFMKIQVHLP NLIDEQKIDSWIYRITRNTIIDFYRTKKTSEILPDVLHFNDSAEEENFTKEATVCIRS TIKRLPEKYREALELTDFQGLSQKELSEKLGISYSGAKSRVQRGRGKLKQLLEGCCHI EADRYGNIVDFRILKE*" gene complement(2607842..2608372) /gene="sigZ" /locus_tag="BSU_26840" /old_locus_tag="BSU26840" promotor_-10 complement(2608418..2608437) /Source="Nicolas_upshift_promotors" /id="U2067" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.519480519480519" /psig="0.996003996003996" /xcortree=1905 /SigmaFactorBS="acctctcctttatcattatttttggcaacagctgcaatacaa tTGATTCAAcaattgtttgctcTTTGTTACGATTAAAAAGACgaagcaaatgtaaagc a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2608441) /Source="Nicolas_upshifts" /id="U2067" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.519480519480519" /psig="0.996003996003996" /xcortree=1905 /SigmaFactorBS="acctctcctttatcattatttttggcaacagctgcaatacaa tTGATTCAAcaattgtttgctcTTTGTTACGATTAAAAAGACgaagcaaatgtaaagc a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(2608451..2608458) /Source="Nicolas_upshift_promotors" /id="U2067" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.519480519480519" /psig="0.996003996003996" /xcortree=1905 /SigmaFactorBS="acctctcctttatcattatttttggcaacagctgcaatacaa tTGATTCAAcaattgtttgctcTTTGTTACGATTAAAAAGACgaagcaaatgtaaagc a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" CDS 2608507..2609487 /gene="yrpG" /locus_tag="BSU_26850" /old_locus_tag="BSU26850" /EC_number="1.1.-.-" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 23990306, 25326299; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative aldo-keto reductase" /protein_id="NP_390562.2" /db_xref="EnsemblGenomes-Gn:BSU26850" /db_xref="EnsemblGenomes-Tr:CAB14626" /db_xref="GOA:O05408" /db_xref="InterPro:IPR023210" /db_xref="InterPro:IPR036812" /db_xref="SubtiList:BG12309" /db_xref="UniProtKB/Swiss-Prot:O05408" /translation="MEYTYLGRTGLRVSRLCLGTMNFGVDTDEKTAFRIMDEALDNGI QFFDTANIYGWGKNAGLTESIIGKWFAQGGQRREKVVLATKVYEPISDPNDGPNDMRG LSLYKIRRHLEGSLKRLQTDHIELYQMHHIDRRTPWDEIWEAFETQVRSGKVDYIGSS NFAGWHLVKAQAEAEKRRFMGLVTEQHKYSLLERTAEMEVLPAARDLGLGVVAWSPLA GGLLGGKALKSNAGTRTAKRADLIEKHRLQLEKFSDLCKELGEKEANVALAWVLANPV LTAPIIGPRTVEQLRDTIKAVEISLDKEILRMLNDIFPGPGGETPEAYAW*" gene 2608507..2609487 /gene="yrpG" /locus_tag="BSU_26850" /old_locus_tag="BSU26850" CDS complement(2609761..2611077) /gene="yraO" /locus_tag="BSU_26860" /old_locus_tag="BSU26860" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 11053381, 11566984, 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative citrate transporter" /protein_id="NP_390563.1" /db_xref="EnsemblGenomes-Gn:BSU26860" /db_xref="EnsemblGenomes-Tr:CAB14627" /db_xref="GOA:O05407" /db_xref="InterPro:IPR004680" /db_xref="InterPro:IPR014738" /db_xref="SubtiList:BG12279" /db_xref="UniProtKB/Swiss-Prot:O05407" /translation="MLTILGFSMVTVFTILIMTKKVSPIVALTITPIVFALIGGFGKG IGDMILEGIQTVASSAALLLFAILFFGILIDAGLFDPLIEKILSIVKGDPVKIAIGSA VLAMLIALDGDGTTTYMITVSAMLPLYKRIGMNPMVMATLAMLSLSIVSGMTPWGGPA TRAISVLGLDPSDFFVPLLPTMLGGIACVIFLAFLMGRKERNRIGIVQLEPRHITKDS SQSYMAATLESEQLKRPRLIYLNLFLVISIMVFIVLGTKHPSVLFLIGFVLALTINYP NVKMQKERIAEHSGNAITVVLLVFSAGVFAGILSGTKMVDAIAGSLISIIPSSMGGFF PVIVALTSIPFTFVLSNDAYYFGMVPIFAEAASAYGIEPVEIARASIMGQPVHLMSPL VASTVLLVSMLKMDLGSFQRFAVKWAVITSLVITLLAIITGAITIL*" gene complement(2609761..2611077) /gene="yraO" /locus_tag="BSU_26860" /old_locus_tag="BSU26860" S_feature complement(2611078..2611191) /Source="Nicolas_S_feature" /locus_tag="new_2745480_2745593_c" /HighExp="Lbtran, M40t90, Lbstat, HiTm, Mal, Gly, M0t90, S1, T1.0H, Fru" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.998" /TUlongSig="NA" /TUlongPSig="NA" /label="S1012" CDS complement(2611192..2612061) /gene="yraN" /locus_tag="BSU_26870" /old_locus_tag="BSU26870" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 20011599; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative transcriptional regulator (probes citrate or citrate-related metabolite)" /protein_id="NP_390564.1" /db_xref="EnsemblGenomes-Gn:BSU26870" /db_xref="EnsemblGenomes-Tr:CAB14628" /db_xref="GOA:O07906" /db_xref="InterPro:IPR000847" /db_xref="InterPro:IPR005119" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG12278" /db_xref="UniProtKB/Swiss-Prot:O07906" /translation="MDEKDWILLKILHEEQSVTKTAERLFTSQPSITYRLKKIEEIFG IELFTKRHKGITFTAEGEHLVAYARRMLQELQDTKDHISNLSKEVQGHLRLGVSSNFA QYKLPKLLREFSTMYPNVQYSVQTGWSTDVMKLLDAGIVQVGILRGSHRWKGVEERLT REKLHIISKKPITIEQLPFLPFIKYKTDASLKTIIEDWMHTNLKQAPIIAMEVDRQET CKEMVKHGLGYSIAPEICLQESDHLYTMELYNAKGKPLMRDTWLMYDQKSLGIKLVKA FIDFLKGEQMVTI*" gene complement(2611192..2612061) /gene="yraN" /locus_tag="BSU_26870" /old_locus_tag="BSU26870" promotor_-10 complement(2612084..2612103) /Source="Nicolas_upshift_promotors" /id="U2068" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.318681318681319" /psig="0.998001998001998" /xcortree=3210 /SigmaFactorBS="gtgtagaaggtaaaaaaataaaaataaaatataagtttTCTT AAtattcgataaaaaaACTTTTATAATTGTGAAAGAaggactagaaaggaagatgaaa a" /listShort="yraN, S1012, yraO" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2612101) /Source="Nicolas_upshifts" /id="U2068" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.318681318681319" /psig="0.998001998001998" /xcortree=3210 /SigmaFactorBS="gtgtagaaggtaaaaaaataaaaataaaatataagtttTCTT AAtattcgataaaaaaACTTTTATAATTGTGAAAGAaggactagaaaggaagatgaaa a" /listShort="yraN, S1012, yraO" /GFF_Attribute="listLong" promotor_-35 complement(2612118..2612123) /Source="Nicolas_upshift_promotors" /id="U2068" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.318681318681319" /psig="0.998001998001998" /xcortree=3210 /SigmaFactorBS="gtgtagaaggtaaaaaaataaaaataaaatataagtttTCTT AAtattcgataaaaaaACTTTTATAATTGTGAAAGAaggactagaaaggaagatgaaa a" /listShort="yraN, S1012, yraO" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(2612168..2612169) /Source="Nicolas_upshift_promotors" /id="U2069" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.367632367632368" /psig="0.537462537462537" /xcortree=645 /SigmaFactorBS="ctctcatgattgttacattcgtcttgaccATcgtcatcatcc tcatcttaaAGGTAGTATTTtttatGTtttttagtgtagaaggtaaaaaaataaaaat a" /listShort="yraN" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2612176) /Source="Nicolas_upshifts" /id="U2069" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.367632367632368" /psig="0.537462537462537" /xcortree=645 /SigmaFactorBS="ctctcatgattgttacattcgtcttgaccATcgtcatcatcc tcatcttaaAGGTAGTATTTtttatGTtttttagtgtagaaggtaaaaaaataaaaat a" /listShort="yraN" /GFF_Attribute="listLong" promotor_-35 complement(2612206..2612207) /Source="Nicolas_upshift_promotors" /id="U2069" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.367632367632368" /psig="0.537462537462537" /xcortree=645 /SigmaFactorBS="ctctcatgattgttacattcgtcttgaccATcgtcatcatcc tcatcttaaAGGTAGTATTTtttatGTtttttagtgtagaaggtaaaaaaataaaaat a" /listShort="yraN" /GFF_Attribute="listLong" /label="promotor_-35" CDS 2612206..2613309 /gene="prpF" /locus_tag="BSU_26880" /old_locus_tag="BSU26880" /EC_number="5.3.3.7" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2b: Function from indirect experimental evidences (e.g. phenotypes); PubMedId: 11294638, 12473114, 14702315, 17567742; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="aconitate isomerase" /protein_id="NP_390565.2" /db_xref="EnsemblGenomes-Gn:BSU26880" /db_xref="EnsemblGenomes-Tr:CAB14629" /db_xref="GOA:O07931" /db_xref="InterPro:IPR007400" /db_xref="SubtiList:BG12277" /db_xref="UniProtKB/Swiss-Prot:O07931" /translation="MVKTNVTIMRGGTSKGVFFHESAMPNNKNEWEPFLLDVMGSPDK RQIDGLGGGNSLTSKVAIIKKAYTSDIDVHYTFGQVSISEEKVDFKGNCGNISAAVGP FAIEEGLVKAKEPMTAVRILNTNTNKMIIAEVEVEDGQVKYDGDVTISGVPGSGSPIY LNFHDAAGSVTGHLLPTGNSSEFLDTSQGQIEVSIIDYANPLVFVEASSIGLDGTELA EEFTDLQLAQFEELRSIAAEKCGFASRFSATKLSPAVPKLAIVAKPEKYKDSTGAWHS SVEMDLHIRMMSMQKPHQALAVTGAICTTRALSVEGAIPARIAKNHSTKVRLAHSSGI IETMVEPTGIKIVRTARRIMDGTVYTHGDYQMM*" gene 2612206..2613309 /gene="prpF" /locus_tag="BSU_26880" /old_locus_tag="BSU26880" misc_feature 2613199..2613218 /Source="Nicolas_upshift_promotors" /id="U2070" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.736263736263736" /psig="0.984015984015984" /xcortree=3092 /SigmaFactorBS="atccctgcaagaatagcaaaaaaccactctacaaaggttcgg ctagctcattctTCTGGTATTATTGAAACAATggtggagcccactggtataaagatcg t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 2613205 /Source="Nicolas_upshifts" /id="U2070" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.736263736263736" /psig="0.984015984015984" /xcortree=3092 /SigmaFactorBS="atccctgcaagaatagcaaaaaaccactctacaaaggttcgg ctagctcattctTCTGGTATTATTGAAACAATggtggagcccactggtataaagatcg t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" downshifts complement(2613556) /Source="Nicolas_upshifts" /id="D1374" /incds=0 /nref=123 /ntot=254 /MaxReadThrough="2.33762" /MaxDrop="7.47213" /score="6.31571576" /energy="-8.7" /TU="U2071" /idTUdmin="U2071" /TUdmin="-33" /isTUend="FALSE" CDS complement(2613582..2614415) /gene="csn" /locus_tag="BSU_26890" /old_locus_tag="BSU26890" /EC_number="3.2.1.132" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:11065371, 11320136, 1664582, 25355936" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11065371, 11320136, 1664582, 25355936; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="chitosanase" /protein_id="NP_390566.1" /db_xref="EnsemblGenomes-Gn:BSU26890" /db_xref="EnsemblGenomes-Tr:CAB14630" /db_xref="GOA:O07921" /db_xref="InterPro:IPR000400" /db_xref="InterPro:IPR023346" /db_xref="SubtiList:BG11923" /db_xref="UniProtKB/Swiss-Prot:O07921" /translation="MKISMQKADFWKKAAISLLVFTMFFTLMMSETVFAAGLNKDQKR RAEQLTSIFENGTTEIQYGYVERLDDGRGYTCGRAGFTTATGDALEVVEVYTKAVPNN KLKKYLPELRRLAKEESDDTSNLKGFASAWKSLANDKEFRAAQDKVNDHLYYQPAMKR SDNAGLKTALARAVMYDTVIQHGDGDDPDSFYALIKRTNKKAGGSPKDGIDEKKWLNK FLDVRYDDLMNPANHDTRDEWRESVARVDVLRSIAKENNYNLNGPIHVRSNEYGNFVI K*" gene complement(2613582..2614415) /gene="csn" /locus_tag="BSU_26890" /old_locus_tag="BSU26890" misc_feature complement(2614445..2614464) /Source="Nicolas_upshift_promotors" /id="U2071" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.84015984015984" /psig="0.992007992007992" /xcortree=504 /SigmaFactorBS="agattcaaaatattgacaaattgatgtattttcaacaatagg gcagtttcTTCATGTATACTGAGTCTGTatttacaatatttagaaaggggaagtgaaa t" /listShort="csn" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(2614454) /Source="Nicolas_upshifts" /id="U2071" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.84015984015984" /psig="0.992007992007992" /xcortree=504 /SigmaFactorBS="agattcaaaatattgacaaattgatgtattttcaacaatagg gcagtttcTTCATGTATACTGAGTCTGTatttacaatatttagaaaggggaagtgaaa t" /listShort="csn" /GFF_Attribute="listLong" promotor_-35 2614620..2614624 /Source="Nicolas_upshift_promotors" /id="U2072" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.450549450549451" /psig="0.992007992007992" /xcortree=490 /SigmaFactorBS="gggaaggtcccttgattttcatactgcttcaactttcattaa caaGATGCcataaggctttactCTATTTTATAATGGAAGTGAtcatcgaaaatcgtta g" /listShort="S1013, yraL" /GFF_Attribute="listLong" /label="promotor_-35" S_feature 2614635..2614857 /Source="Nicolas_S_feature" /locus_tag="new_2749037_2749259" /HighExp="Lbstat, M9-stat, B60, M0t90, M40t90, T1.30H, T2.0H, T3.0H, T2.30H, T1.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.97565800000000003" /TUshortSig="SigA" /TUshortPSig="0.992" /TUlongSig="NA" /TUlongPSig="NA" /label="S1013" upshifts 2614635 /Source="Nicolas_upshifts" /id="U2072" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.450549450549451" /psig="0.992007992007992" /xcortree=490 /SigmaFactorBS="gggaaggtcccttgattttcatactgcttcaactttcattaa caaGATGCcataaggctttactCTATTTTATAATGGAAGTGAtcatcgaaaatcgtta g" /listShort="S1013, yraL" /GFF_Attribute="listLong" promotor_-10 2614639..2614658 /Source="Nicolas_upshift_promotors" /id="U2072" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.450549450549451" /psig="0.992007992007992" /xcortree=490 /SigmaFactorBS="gggaaggtcccttgattttcatactgcttcaactttcattaa caaGATGCcataaggctttactCTATTTTATAATGGAAGTGAtcatcgaaaatcgtta g" /listShort="S1013, yraL" /GFF_Attribute="listLong" /label="promotor_-10" CDS 2614858..2615121 /gene="yraL" /locus_tag="BSU_26900" /old_locus_tag="BSU26900" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_390567.1" /db_xref="EnsemblGenomes-Gn:BSU26900" /db_xref="EnsemblGenomes-Tr:CAB14631" /db_xref="GOA:O07917" /db_xref="InterPro:IPR009057" /db_xref="SubtiList:BG12276" /db_xref="UniProtKB/Swiss-Prot:O07917" /translation="MAYVKATAILPEKLISEIQKYVQGKTIYIPKPESSHQKWGACSG TRKLIDDRNASIKKAFKNGKTIHQLSDEYHLSIETIKKIVYSK*" gene 2614858..2615121 /gene="yraL" /locus_tag="BSU_26900" /old_locus_tag="BSU26900" downshifts 2615109 /Source="Nicolas_upshifts" /id="D1375" /incds=0 /nref=71 /ntot=223 /MaxReadThrough="1.7419" /MaxDrop="4.94534" /score="-1.04752822" /energy="-9.9" /TU="NA" /idTUdmin="U2072" /TUdmin="-10" /isTUend="TRUE" CDS 2615258..2616073 /gene="yraK" /locus_tag="BSU_26910" /old_locus_tag="BSU26910" /function="18.1: Enzymes of unknown specificity" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative hydrolase" /protein_id="NP_390568.2" /db_xref="EnsemblGenomes-Gn:BSU26910" /db_xref="EnsemblGenomes-Tr:CAB14632" /db_xref="GOA:O07937" /db_xref="InterPro:IPR000073" /db_xref="InterPro:IPR029058" /db_xref="SubtiList:BG12275" /db_xref="UniProtKB/Swiss-Prot:O07937" /translation="MTINNGTLQVPGANIHYQVRGSGPIILLVHGGGGDADKFHHVAN HLANWYTVVTYDRRGHSRSNLANQIEGYRVETHSDDAHRLLAKITNKPAYVFGSSSGA VIGLDLCIRHPEQVHVMIPHEPILLQLLHGNELKQAEQFMEDLKKNHRSEVIKLMSRL ETDEQSKAVLTKRLLGNSTYFTEYEIQGILSYTLDFEALKTVFTSSPMKILPAGGSAS RELFPYRCANALAEQLETEWVEFPGNHTGYTMYHKEFSERLHDMLEKEKKHTC*" gene 2615258..2616073 /gene="yraK" /locus_tag="BSU_26910" /old_locus_tag="BSU26910" S_feature complement(2616408..2616480) /Source="Nicolas_S_feature" /locus_tag="new_2750810_2750882_c" /HighExp="BC, Lbstat, Sw, M40t90, M0t90, S2, BI, BT, S3, S4" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="NA" /TUshortPSig="NA" /TUlongSig="NA" /TUlongPSig="NA" /label="S1014" downshifts complement(2616451) /Source="Nicolas_upshifts" /id="D1376" /incds=0 /nref=44 /ntot=205 /MaxReadThrough="1.43644" /MaxDrop="4.78753" /score="-0.984762906" /energy="-12.6" /TU="NA" /idTUdmin="U2073" /TUdmin="-1" /isTUend="TRUE" CDS complement(2616481..2616837) /gene="yraJ" /locus_tag="BSU_26920" /old_locus_tag="BSU26920" /function="18: Unknown function" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_390569.2" /db_xref="EnsemblGenomes-Gn:BSU26920" /db_xref="EnsemblGenomes-Tr:CAB14633" /db_xref="InterPro:IPR003646" /db_xref="SubtiList:BG12274" /db_xref="UniProtKB/Swiss-Prot:O07934" /translation="MTKLKMLSMLTVMIASLFIFSSQALAVQYFTVSTSSGAPVNMRS GPGTNYPIMLSIPSGSRVPYYCYAYGTTVTGKYGTSNIWDQIQWKDSRGVVNIGYVSD TYVYTGSDGPVGYKCN*" gene complement(2616481..2616837) /gene="yraJ" /locus_tag="BSU_26920" /old_locus_tag="BSU26920" CDS complement(2616890..2617249) /gene="yraI" /locus_tag="BSU_26930" /old_locus_tag="BSU26930" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_390570.2" /db_xref="EnsemblGenomes-Gn:BSU26930" /db_xref="EnsemblGenomes-Tr:CAB14634" /db_xref="InterPro:IPR003646" /db_xref="SubtiList:BG12273" /db_xref="UniProtKB/Swiss-Prot:O07909" /translation="MNKLKRLSMLTVMIASVFIFSSHALAAQYYTVSTSSGAPVNMRS GPGTSWGIVTTIPSGTRIPIYCYKTGTTVTGKYGTSNIWNYTERTLASGEIVPGFVSD TYMYTGSDGPVVPKCSW*" gene complement(2616890..2617249) /gene="yraI" /locus_tag="BSU_26930" /old_locus_tag="BSU26930" misc_feature complement(2617342..2617361) /Source="Nicolas_upshift_promotors" /id="U2073" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.487512487512487" /psig="0.99100899100899" /xcortree=492 /SigmaFactorBS="tccttaattgtcgaaaacataggaataattccacttttgaaa gatctagttTATGGTACATTGATAAATATatgggaggggagggggcatggtatctgaa a" /listShort="yraI, yraJ" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(2617352) /Source="Nicolas_upshifts" /id="U2073" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.487512487512487" /psig="0.99100899100899" /xcortree=492 /SigmaFactorBS="tccttaattgtcgaaaacataggaataattccacttttgaaa gatctagttTATGGTACATTGATAAATATatgggaggggagggggcatggtatctgaa a" /listShort="yraI, yraJ" /GFF_Attribute="listLong" CDS complement(2617521..2617622) /locus_tag="BSU_26935" /old_locus_tag="BSU26935" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_009513987.1" /translation="MIGEKGGVSMNREEAWIQGSSTLIELIGGNEAA*" gene complement(2617521..2617622) /locus_tag="BSU_26935" /old_locus_tag="BSU26935" S_feature complement(2617662..2617764) /Source="Nicolas_S_feature" /locus_tag="new_2752064_2752166_c" /HighExp="M40t90, LBGstat, M40t45, M0t90, Lbstat, Lbtran, LBGtran, LPhT, ferm, S8" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.575" /TUlongSig="NA" /TUlongPSig="NA" /label="S1015" downshifts complement(2617704) /Source="Nicolas_upshifts" /id="D1377" /incds=0 /nref=19 /ntot=188 /MaxReadThrough="2.12056" /MaxDrop="4.09264" /score="-0.984762906" /energy="-12.6" /TU="NA" /idTUdmin="U2074" /TUdmin=0 /isTUend="TRUE" CDS complement(2617765..2618151) /gene="yraH" /locus_tag="BSU_26940" /old_locus_tag="BSU26940" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative lyase" /protein_id="NP_390571.1" /db_xref="EnsemblGenomes-Gn:BSU26940" /db_xref="EnsemblGenomes-Tr:CAB14635" /db_xref="GOA:O07918" /db_xref="InterPro:IPR004360" /db_xref="InterPro:IPR018146" /db_xref="InterPro:IPR029068" /db_xref="SubtiList:BG12272" /db_xref="UniProtKB/Swiss-Prot:O07918" /translation="MKLLQIRLLVNDFKKSVEFYKDSLGLPISWLENEMEYALFDNGE TKIELLSRETMAEIVGEEKKSLEGEAQSKFLLQFKVEDVDKTYDDLHEKGVKCENKPH DRKEWSARVAHFRDPDHNLIEIYKML*" gene complement(2617765..2618151) /gene="yraH" /locus_tag="BSU_26940" /old_locus_tag="BSU26940" misc_feature complement(2618193..2618209) /Source="Nicolas_upshift_promotors" /id="U2074" /multdbtbs="-" /comp="M18" /sig="SigA" /pcomp="0.245754245754246" /psig="0.575424575424575" /xcortree=1510 /SigmaFactorBS="tgcacttaaatctgaaataagggtgaagtatggaaacttgac atagtgctgtcaggtttcTTTGGTATCATTAAATTggatgaccagtaaaagtatggtt t" /listShort="yraH, S1015" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(2618209) /Source="Nicolas_upshifts" /id="U2074" /multdbtbs="-" /comp="M18" /sig="SigA" /pcomp="0.245754245754246" /psig="0.575424575424575" /xcortree=1510 /SigmaFactorBS="tgcacttaaatctgaaataagggtgaagtatggaaacttgac atagtgctgtcaggtttcTTTGGTATCATTAAATTggatgaccagtaaaagtatggtt t" /listShort="yraH, S1015" /GFF_Attribute="listLong" promotor_-35 2618342..2618348 /Source="Nicolas_upshift_promotors" /id="U2075" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp="0.98001998001998" /psig="0.98001998001998" /xcortree=887 /SigmaFactorBS="gcgattcttaaaacaaaaaatgataccgagtgtattttcTGT ATGCttcaacttcatttcGGGAAATGTAACgttgataaaaggaggttacatcaatatg g" /listShort="yraG, yraF, adhB, yraE, yraD" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2618363..2618374 /Source="Nicolas_upshift_promotors" /id="U2075" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp="0.98001998001998" /psig="0.98001998001998" /xcortree=887 /SigmaFactorBS="gcgattcttaaaacaaaaaatgataccgagtgtattttcTGT ATGCttcaacttcatttcGGGAAATGTAACgttgataaaaggaggttacatcaatatg g" /listShort="yraG, yraF, adhB, yraE, yraD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2618363 /Source="Nicolas_upshifts" /id="U2075" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp="0.98001998001998" /psig="0.98001998001998" /xcortree=887 /SigmaFactorBS="gcgattcttaaaacaaaaaatgataccgagtgtattttcTGT ATGCttcaacttcatttcGGGAAATGTAACgttgataaaaggaggttacatcaatatg g" /listShort="yraG, yraF, adhB, yraE, yraD" /GFF_Attribute="listLong" CDS 2618400..2618645 /gene="yraG" /locus_tag="BSU_26950" /old_locus_tag="BSU26950" /function="16.5: Explore" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 10066829, 22882546; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="putative spore coat protein" /protein_id="NP_390572.1" /db_xref="EnsemblGenomes-Gn:BSU26950" /db_xref="EnsemblGenomes-Tr:CAB14636" /db_xref="GOA:O07919" /db_xref="InterPro:IPR012347" /db_xref="SubtiList:BG12271" /db_xref="UniProtKB/Swiss-Prot:O07919" /translation="MDHQTLAAHEAVDLHEIVNFKTLCIAKSKLMQGLVFDQELKDLM EKDVQQSIQDLTELQAVYERASFQAPVPQSRPTPIIN*" gene 2618400..2618645 /gene="yraG" /locus_tag="BSU_26950" /old_locus_tag="BSU26950" CDS 2618663..2619031 /gene="yraF" /locus_tag="BSU_26960" /old_locus_tag="BSU26960" /function="16.5: Explore" /function="16.13: Shape" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 10066829, 22882546; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="putative spore coat protein" /protein_id="NP_390573.1" /db_xref="EnsemblGenomes-Gn:BSU26960" /db_xref="EnsemblGenomes-Tr:CAB14637" /db_xref="GOA:O07949" /db_xref="InterPro:IPR012347" /db_xref="InterPro:IPR012851" /db_xref="SubtiList:BG12270" /db_xref="UniProtKB/Swiss-Prot:O07949" /translation="MNNDHLDPINSLNVPELADTTFAMDFLIRAKEGVRNTAVALTET ASPDVRALLRKQLMQGIAMHQEITELMISKKWFHPYELSEQYKLDQLSAKNTIMVGNM NLFPDETNRKGMFDRTPDEH*" gene 2618663..2619031 /gene="yraF" /locus_tag="BSU_26960" /old_locus_tag="BSU26960" CDS 2619050..2620186 /gene="adhB" /locus_tag="BSU_26970" /old_locus_tag="BSU26970" /EC_number="1.1.1.-" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 7926692, 17586670; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative oxidoreductase (involving bacillithiol)" /protein_id="NP_390574.2" /db_xref="EnsemblGenomes-Gn:BSU26970" /db_xref="EnsemblGenomes-Tr:CAB14638" /db_xref="GOA:O06012" /db_xref="InterPro:IPR002328" /db_xref="InterPro:IPR011032" /db_xref="InterPro:IPR013149" /db_xref="InterPro:IPR013154" /db_xref="InterPro:IPR027399" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG11902" /db_xref="UniProtKB/Swiss-Prot:O06012" /translation="MKAVTYQGIKNVVVKDVPDPKIEKSDDMIIKVTSTAICGSDLHL IHGFIPNMQEDYVIGHEPMGIVEEVGSGVTKLKKGDRVIIPFNIACGECFFCKNQLES QCDQSNDNGEMGAYFGYSGQTGGYPGGQAEYLRVPFANFTHFKIPESCEEPDEKLSVI ADAMTTGFWSVDNAGVKKGDTVIVLGCGPVGLFAQKFCWLKGAKRVIAVDYVNYRLQH AKRTNKVEIVNFEDHENTGNYLKEITKGGADVVIDAVGMDGKMSDLEFLASGLKLHGG TMSALVIASQAVRKGGTIQITGVYGGRYNGFPLGDIMQRNVNIRSGQAPVIHYMPYMF ELVSTGKIDPGDVVSHVLPLSEAKHGYDIFDSKMDDCIKVVLKP*" gene 2619050..2620186 /gene="adhB" /locus_tag="BSU_26970" /old_locus_tag="BSU26970" CDS 2620205..2620402 /gene="yraE" /locus_tag="BSU_26980" /old_locus_tag="BSU26980" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 10066829, 22882546; Product type s: structure" /codon_start=1 /transl_table=11 /product="putative spore coat protein" /protein_id="NP_390575.1" /db_xref="EnsemblGenomes-Gn:BSU26980" /db_xref="EnsemblGenomes-Tr:CAB14639" /db_xref="InterPro:IPR012347" /db_xref="SubtiList:BG13780" /db_xref="UniProtKB/Swiss-Prot:O06011" /translation="MEYALHEVLEVQEMTAFKTLCLTKSKTMKALVSDPKLKEIMQQD VDITTRQLQEFASILSNAKQE*" gene 2620205..2620402 /gene="yraE" /locus_tag="BSU_26980" /old_locus_tag="BSU26980" CDS 2620418..2620717 /gene="yraD" /locus_tag="BSU_26990" /old_locus_tag="BSU26990" /function="16.5: Explore" /function="16.13: Shape" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 10066829, 22882546; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="putative spore coat protein" /protein_id="NP_390576.1" /db_xref="EnsemblGenomes-Gn:BSU26990" /db_xref="EnsemblGenomes-Tr:CAB14640" /db_xref="GOA:O06010" /db_xref="InterPro:IPR012347" /db_xref="InterPro:IPR012851" /db_xref="SubtiList:BG13779" /db_xref="UniProtKB/Swiss-Prot:O06010" /translation="MNPIIEYLTGMNVLTDQIIAMDLLISAKNGVRNYAMAATEAGTP EVKEVLIRHLEEALDMHEQLSSYMMEKGWYHPWNPDEQVKLNLKNIDTAIQLPTL*" gene 2620418..2620717 /gene="yraD" /locus_tag="BSU_26990" /old_locus_tag="BSU26990" downshifts 2620708 /Source="Nicolas_upshifts" /id="D1378" /incds=0 /nref=11 /ntot=39 /MaxReadThrough="1.62449" /MaxDrop="3.8153" /score="-8.57687054" /energy="-10.7" /TU="NA" /idTUdmin="U2075" /TUdmin=0 /isTUend="TRUE" CDS complement(2620980..2621402) /gene="adhR" /locus_tag="BSU_27000" /old_locus_tag="BSU27000" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:14663075, 17962296, 19170879" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 14663075, 17962296, 19170879; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator regulated by thiol-alkylation" /protein_id="NP_390578.2" /db_xref="EnsemblGenomes-Gn:BSU27000" /db_xref="EnsemblGenomes-Tr:CAB14642" /db_xref="GOA:O06008" /db_xref="InterPro:IPR000551" /db_xref="InterPro:IPR009061" /db_xref="SubtiList:BG13777" /db_xref="UniProtKB/Swiss-Prot:O06008" /translation="MNIAQVAKQFGLTAATLRYYERVGLIPPVKRKDSGIRDYDEEDI KWIEFIKCMRNAGLSIEALIEYTTLFTEGDRTVEARKNILADERQRLIEKRKEIDETI KRLDTKIKDYDGKLRENEAKLKSRPKTESLHGSVEQRR*" gene complement(2620980..2621402) /gene="adhR" /locus_tag="BSU_27000" /old_locus_tag="BSU27000" promotor_-35 2621400..2621403 /Source="Nicolas_upshift_promotors" /id="U2076" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.547452547452547" /psig="0.926073926073926" /xcortree=2007 /SigmaFactorBS="aactgctttgccacctgagcaatattCATGatcttcacctct ctaTCCTGTATGTTGTGAAGGTAacacttaaagttaactttaagtcaagctcaaaaca a" /listShort="S1016, yrzP, S1017, adhA" /listLong="yraA, S1018" /label="promotor_-35" promotor_-10 2621419..2621438 /Source="Nicolas_upshift_promotors" /id="U2076" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.547452547452547" /psig="0.926073926073926" /xcortree=2007 /SigmaFactorBS="aactgctttgccacctgagcaatattCATGatcttcacctct ctaTCCTGTATGTTGTGAAGGTAacacttaaagttaactttaagtcaagctcaaaaca a" /listShort="S1016, yrzP, S1017, adhA" /listLong="yraA, S1018" /label="promotor_-10" S_feature 2621434..2621584 /Source="Nicolas_S_feature" /locus_tag="new_2755836_2755986" /HighExp="Diami, dia15, dia5, H2O2, S8, Paraq, S5, G180, S6, G135" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.926" /TUlongSig="NA" /TUlongPSig="NA" /label="S1016" upshifts 2621434 /Source="Nicolas_upshifts" /id="U2076" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.547452547452547" /psig="0.926073926073926" /xcortree=2007 /SigmaFactorBS="aactgctttgccacctgagcaatattCATGatcttcacctct ctaTCCTGTATGTTGTGAAGGTAacacttaaagttaactttaagtcaagctcaaaaca a" /listShort="S1016, yrzP, S1017, adhA" /listLong="yraA, S1018" promotor_-10 complement(2621437..2621456) /Source="Nicolas_upshift_promotors" /id="U2077" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.947052947052947" /psig="0.984015984015984" /xcortree=2044 /SigmaFactorBS="tatataaacccagattcagcagctaacCACTTGTTttgagct tgacttAAAGTTAACTTTAAGTGTTAccttcacaacatacaggatagagaggtgaaga t" /listShort="yraB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2621444) /Source="Nicolas_upshifts" /id="U2077" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.947052947052947" /psig="0.984015984015984" /xcortree=2044 /SigmaFactorBS="tatataaacccagattcagcagctaacCACTTGTTttgagct tgacttAAAGTTAACTTTAAGTGTTAccttcacaacatacaggatagagaggtgaaga t" /listShort="yraB" /GFF_Attribute="listLong" promotor_-35 complement(2621470..2621477) /Source="Nicolas_upshift_promotors" /id="U2077" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.947052947052947" /psig="0.984015984015984" /xcortree=2044 /SigmaFactorBS="tatataaacccagattcagcagctaacCACTTGTTttgagct tgacttAAAGTTAACTTTAAGTGTTAccttcacaacatacaggatagagaggtgaaga t" /listShort="yraB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(2621553..2621572) /Source="Nicolas_upshift_promotors" /id="U2078" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.975024975024975" /psig="0.99000999000999" /xcortree=630 /SigmaFactorBS="ctaattgttctcttccggcagtgtgttTATTTGCCattcagc aatccctCCAACTACACTGTTTTTAGTgcatggagaagtatagagtttaaagtgtgct t" /GFF_Attribute="listShort" /listLong="yraB" /label="promotor_-10" upshifts complement(2621561) /Source="Nicolas_upshifts" /id="U2078" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.975024975024975" /psig="0.99000999000999" /xcortree=630 /SigmaFactorBS="ctaattgttctcttccggcagtgtgttTATTTGCCattcagc aatccctCCAACTACACTGTTTTTAGTgcatggagaagtatagagtttaaagtgtgct t" /GFF_Attribute="listShort" /listLong="yraB" CDS 2621585..2621779 /gene="yrzP" /locus_tag="BSU_27009" /old_locus_tag="BSU27009" /EC_number="4.1.1.44" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 17962296, 19170879; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative carboxymuconolactone decarboxylase" /protein_id="YP_009513988.1" /db_xref="EnsemblGenomes-Gn:BSU27009" /db_xref="EnsemblGenomes-Tr:CAX52671" /db_xref="InterPro:IPR029032" /db_xref="UniProtKB/TrEMBL:C0H460" /translation="MANKHTAGREQLGEFAPKFAELHDDVLFGDIWAREEELSSRDRS MITVSALITDCFSAYKSGSF*" gene 2621585..2621779 /gene="yrzP" /locus_tag="BSU_27009" /old_locus_tag="BSU27009" promotor_-35 complement(2621587..2621594) /Source="Nicolas_upshift_promotors" /id="U2078" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.975024975024975" /psig="0.99000999000999" /xcortree=630 /SigmaFactorBS="ctaattgttctcttccggcagtgtgttTATTTGCCattcagc aatccctCCAACTACACTGTTTTTAGTgcatggagaagtatagagtttaaagtgtgct t" /GFF_Attribute="listShort" /listLong="yraB" /label="promotor_-35" promotor_-35 2621797..2621804 /Source="Nicolas_upshift_promotors" /id="U2079" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.952047952047952" /psig="0.987012987012987" /xcortree=2722 /SigmaFactorBS="atcaggttcattttaaatggtttttttaaaaaaCCCTTGCCt taaagcagactttaAGGTTTATCGTTATGTTGAAgacaccataaaacataaataagtg c" /listShort="S1017, adhA" /listLong="yraA" /label="promotor_-35" promotor_-10 2621820..2621839 /Source="Nicolas_upshift_promotors" /id="U2079" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.952047952047952" /psig="0.987012987012987" /xcortree=2722 /SigmaFactorBS="atcaggttcattttaaatggtttttttaaaaaaCCCTTGCCt taaagcagactttaAGGTTTATCGTTATGTTGAAgacaccataaaacataaataagtg c" /listShort="S1017, adhA" /listLong="yraA" /label="promotor_-10" upshifts 2621824 /Source="Nicolas_upshifts" /id="U2079" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.952047952047952" /psig="0.987012987012987" /xcortree=2722 /SigmaFactorBS="atcaggttcattttaaatggtttttttaaaaaaCCCTTGCCt taaagcagactttaAGGTTTATCGTTATGTTGAAgacaccataaaacataaataagtg c" /listShort="S1017, adhA" /listLong="yraA" S_feature 2621825..2621909 /Source="Nicolas_S_feature" /locus_tag="new_2756227_2756311" /HighExp="LBGstat, dia15, Diami, LPhT, LBGtran, dia5, M40t90, Lbtran, H2O2, Lbstat" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="0.987, 0.926" /TUlongSig="NA" /TUlongPSig="NA" /label="S1017" CDS 2621910..2622959 /gene="adhA" /locus_tag="BSU_27010" /old_locus_tag="BSU27010" /EC_number="1.1.1.-" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 19170879; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative aldehyde dehydrogenase; carbonyl stressresponse" /protein_id="NP_390579.2" /db_xref="EnsemblGenomes-Gn:BSU27010" /db_xref="EnsemblGenomes-Tr:CAB14643" /db_xref="GOA:C0SPA5" /db_xref="InterPro:IPR002328" /db_xref="InterPro:IPR011032" /db_xref="InterPro:IPR013149" /db_xref="InterPro:IPR013154" /db_xref="InterPro:IPR020843" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG12562" /db_xref="UniProtKB/Swiss-Prot:C0SPA5" /translation="MCNQHQTRVLSVSHAKAKFEQTTIERRGLRPHDVLIDIKFSGIC HSDIHSAFDEWGGGIFPMVPGHEIAGVVTAVGTKVTKLAVGDRVGVGCFVDSCGECEY CLNAEEQFCTKGVVQTYNSVDYDGNPTYGGYSQKIVVTDRFVVRIPDRLEMDVASPLL CAGITTYSPLKHWNVGPGKKVAIVGVGGLGHLAIQFAHAMGAEVTVLSRSMNKKEEAL ELGANHYFATSDPATFTALAGRFDVILNTVSANLDVDAYLSMLRIDGTLVSVGAPAKP DTYSVFSLIMGRRSIAGSLVGGIQETQEMLDFAAEHGIEPKIEVIGADQVDEAYERIL RSDVRYRFVIDISTL*" gene 2621910..2622959 /gene="adhA" /locus_tag="BSU_27010" /old_locus_tag="BSU27010" promotor_-35 2623027..2623034 /Source="Nicolas_upshift_promotors" /id="U2080" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.987012987012987" /psig=1 /xcortree=2035 /SigmaFactorBS="cgaaaaatgatctctttaagcaaatATTTTGAAggccggtca atcttCCTGTTATTCTATGAATAGAgagttattaggagggttttttatgagcaaaaaa a" /listShort="yraA, S1018" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2623049..2623068 /Source="Nicolas_upshift_promotors" /id="U2080" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.987012987012987" /psig=1 /xcortree=2035 /SigmaFactorBS="cgaaaaatgatctctttaagcaaatATTTTGAAggccggtca atcttCCTGTTATTCTATGAATAGAgagttattaggagggttttttatgagcaaaaaa a" /listShort="yraA, S1018" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2623062 /Source="Nicolas_upshifts" /id="U2080" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.987012987012987" /psig=1 /xcortree=2035 /SigmaFactorBS="cgaaaaatgatctctttaagcaaatATTTTGAAggccggtca atcttCCTGTTATTCTATGAATAGAgagttattaggagggttttttatgagcaaaaaa a" /listShort="yraA, S1018" /GFF_Attribute="listLong" CDS 2623090..2623599 /gene="sufL" /locus_tag="BSU_27020" /old_locus_tag="BSU27020" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 12775685, 17257049, 17933887, 24330391, 26774339; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="deglycase; general stress protecting enzyme; protects against methylglyoxal toxicity" /protein_id="NP_390580.2" /db_xref="EnsemblGenomes-Gn:BSU27020" /db_xref="EnsemblGenomes-Tr:CAB14644" /db_xref="GOA:O06006" /db_xref="InterPro:IPR002818" /db_xref="InterPro:IPR006286" /db_xref="InterPro:IPR029062" /db_xref="SubtiList:BG13776" /db_xref="UniProtKB/Swiss-Prot:O06006" /translation="MSKKIAVLVTDQFEDIEYTSPVKAYEEAGYSVVAIDLEAGKEVT GKHGEKVKIDKAISDVDASDFDALLIPGGFSPDLLRADDRPGEFAKAFVENKKPVFAI CHGPQVLIDTDLLKGKDITGYRSIRKDLINAGANYKDAEVVVSHNIVTSRTPDDLEAF NRESLNLLK*" gene 2623090..2623599 /gene="sufL" /locus_tag="BSU_27020" /old_locus_tag="BSU27020" downshifts 2623568 /Source="Nicolas_upshifts" /id="D1379" /incds=0 /nref=178 /ntot=254 /MaxReadThrough="4.08169" /MaxDrop="5.1444" /score="24.8267602" /energy="-16.3" /TU="U2080" /idTUdmin="U2076" /TUdmin=528 /isTUend="FALSE" S_feature 2623613..2624718 /Source="Nicolas_S_feature" /locus_tag="new_2758015_2759120" /HighExp="Diami, dia5, Etha, dia15, LPhT, H2O2, Lbstat, Salt, Fru, Paraq" /AntisenseName="sacC" /AntisenseCor="0.18236909579254801" /AntisenseRegPval="-2.6" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="SigA" /TUlongPSig="0.926" /label="S1018" CDS complement(2623641..2625674) /gene="sacC" /locus_tag="BSU_27030" /old_locus_tag="BSU27030" /EC_number="3.2.1.7" /EC_number="3.2.1.65" /EC_number="3.2.1.80" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:7646030, 8057358, 10217495, 12224641" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7646030, 8057358, 10217495, 12224641; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="levanase" /protein_id="NP_390581.1" /db_xref="EnsemblGenomes-Gn:BSU27030" /db_xref="EnsemblGenomes-Tr:CAB14645" /db_xref="GOA:P05656" /db_xref="InterPro:IPR001362" /db_xref="InterPro:IPR013148" /db_xref="InterPro:IPR013189" /db_xref="InterPro:IPR013320" /db_xref="InterPro:IPR018053" /db_xref="InterPro:IPR023296" /db_xref="PDB:4AZZ" /db_xref="PDB:4B1L" /db_xref="PDB:4B1M" /db_xref="SubtiList:BG10320" /db_xref="UniProtKB/Swiss-Prot:P05656" /translation="MKKRLIQVMIMFTLLLTMAFSADAADSSYYDEDYRPQYHFTPEA NWMNDPNGMVYYAGEYHLFYQYHPYGLQWGPMHWGHAVSKDLVTWEHLPVALYPDEKG TIFSGSAVVDKNNTSGFQTGKEKPLVAIYTQDREGHQVQSIAYSNDKGRTWTKYAGNP VIPNPGKKDFRDPKVFWYEKEKKWVMVLAAGDRILIYTSKNLKQWTYASEFGQDQGSH GGVWECPDLFELPVDGNPNQKKWVMQVSVGNGAVSGGSGMQYFVGDFDGTHFKNENPP NKVLWTDYGRDFYAAVSWSDIPSTDSRRLWLGWMSNWQYANDVPTSPWRSATSIPREL KLKAFTEGVRVVQTPVKELETIRGTSKKWKNLTISPASHNVLAGQSGDAYEINAEFKV SPGSAAEFGFKVRTGENQFTKVGYDRRNAKLFVDRSESGNDTFNPAFNTGKETAPLKP VNGKVKLRIFVDRSSVEVFGNDGKQVITDIILPDRSSKGLELYAANGGVKVKSLTIHP LKKVWGTTPFMSNMTGWTTVNGTWADTIEGKQGRSDGDSFILSSASGSDFTYESDITI KDGNGRGAGALMFRSDKDAKNGYLANVDAKHDLVKFFKFENGAASVIAEYKTPIDVNK KYHLKTEAEGDRFKIYLDDRLVIDAHDSVFSEGQFGLNVWDATAVFQNVTKES*" gene complement(2623641..2625674) /gene="sacC" /locus_tag="BSU_27030" /old_locus_tag="BSU27030" downshifts complement(2623666) /Source="Nicolas_upshifts" /id="D1380" /incds=0 /nref=14 /ntot=60 /MaxReadThrough="0.56875" /MaxDrop="5.09923" /score="-2.07442916" /energy="-14.2" /TU="NA" /idTUdmin="U2081" /TUdmin=0 /isTUend="TRUE" CDS complement(2625583..2625750) /locus_tag="BSU_27035" /old_locus_tag="BSU27035" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_009513989.1" /translation="MPETDQLAQQSLLKVFKHEERSEGTNEKETDSSHDHVHPAVDYG IFGRCSRFKLL*" gene complement(2625583..2625750) /locus_tag="BSU_27035" /old_locus_tag="BSU27035" S_feature complement(2625675..2625830) /Source="Nicolas_S_feature" /locus_tag="new_2760077_2760232_c" /HighExp="UNK1, Fru, B60, T0.30H, M40t90, M0t90, ferm, LPh, GM-0.2, GM-0.1" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigL" /TUshortPSig="0.886" /TUlongSig="NA" /TUlongPSig="NA" /label="S1019" CDS complement(2625831..2626658) /gene="levG" /locus_tag="BSU_27040" /old_locus_tag="BSU27040" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:2117666, 9033408, 15849754, 16850406" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 2117666, 9033408, 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="phosphotransferase system (PTS) fructose-specific enzyme IID component" /protein_id="NP_390582.1" /db_xref="EnsemblGenomes-Gn:BSU27040" /db_xref="EnsemblGenomes-Tr:CAB14646" /db_xref="GOA:P26382" /db_xref="InterPro:IPR004704" /db_xref="SubtiList:BG10319" /db_xref="UniProtKB/Swiss-Prot:P26382" /translation="MEKEKRLTKKEIFSMFIRSNFLLGSFNFERVQAMGYCYVMIPAI KKLYGPGAKRNEALQRHLEWFNTHPWLTAPIFGVTAAMEEEMANNKGIDGKAISGMKI GLMGPIAGVGDPIFWGTIRPVLAALGASLALGGNIAGPLLFFFLLNAIRLSTKYYGLK YGYVKGMEILQDLAGNRIQKLTEGASILGLFVMGALVSKWTTINIPIVVSRIKDESGK VDVQTVQNVLDSIMPGALPLGLTLLVAWMLRKGVNPLLIICGIFVIGILGYWAGFLA* " gene complement(2625831..2626658) /gene="levG" /locus_tag="BSU_27040" /old_locus_tag="BSU27040" CDS complement(2626679..2627488) /gene="levF" /locus_tag="BSU_27050" /old_locus_tag="BSU27050" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:2117666, 9033408, 15849754, 16850406" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 2117666, 9033408, 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="phosphotransferase system (PTS) fructose-specific enzyme IIC component" /protein_id="NP_390583.1" /db_xref="EnsemblGenomes-Gn:BSU27050" /db_xref="EnsemblGenomes-Tr:CAB14647" /db_xref="GOA:P26381" /db_xref="InterPro:IPR004700" /db_xref="SubtiList:BG10318" /db_xref="UniProtKB/Swiss-Prot:P26381" /translation="MSSLQIILLLIIAAITGIASVLDEGQTHRPLVACTLVGLVLGDL KTGIILGGTLELMALGWMNVGLAMAPDTAIASVISTILVITADQGIGEGIAVAVALAA AGQALTIFVRTITVFFIHRADQYAKAGNIKGIEIMHITAMVFQALRVMIPTLIVALIS VSAVQAFLGNIPDVITKGLQIGGGIIVVVGYAMVINMMNIPYLKPFFYIGFLLAAFTD FNLVGFGALGLCLALLYQQVMQKQSAHGAVAAASDSGSVAVYDDDDDDLDA*" gene complement(2626679..2627488) /gene="levF" /locus_tag="BSU_27050" /old_locus_tag="BSU27050" CDS complement(2627505..2627993) /gene="levE" /locus_tag="BSU_27060" /old_locus_tag="BSU27060" /EC_number="2.7.1.202" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:2117666, 9033408, 9622354, 10589728" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 2117666, 9033408, 9622354, 10589728; Product type t: transporter" /codon_start=1 /transl_table=11 /product="phosphotransferase system (PTS) fructose-specific enzyme IIB component" /protein_id="NP_390584.1" /db_xref="EnsemblGenomes-Gn:BSU27060" /db_xref="EnsemblGenomes-Tr:CAB14648" /db_xref="GOA:P26380" /db_xref="InterPro:IPR004720" /db_xref="InterPro:IPR018455" /db_xref="InterPro:IPR036667" /db_xref="PDB:1BLE" /db_xref="SubtiList:BG10317" /db_xref="UniProtKB/Swiss-Prot:P26380" /translation="MNIVLARIDDRFIHGQILTRWIKVHAADRIIVVSDDIAQDEMRK TLILSVAPSNVKASAVSVSKMAKAFHSPRYEGVTAMLLFENPSDIVSLIEAGVPIKTV NVGGMRFENHRRQITKSVSVTEQDIKAFETLSDKGVKLELRQLPSDASEDFVQILRNV TK*" gene complement(2627505..2627993) /gene="levE" /locus_tag="BSU_27060" /old_locus_tag="BSU27060" CDS complement(2627993..2628433) /gene="levD" /locus_tag="BSU_27070" /old_locus_tag="BSU27070" /EC_number="2.7.1.202" /function="16.3: Control" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:2117666, 9033408" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 2117666, 9033408; Product type t: transporter" /codon_start=1 /transl_table=11 /product="phosphotransferase system (PTS) fructose-specific enzyme IIA component" /protein_id="NP_390585.1" /db_xref="EnsemblGenomes-Gn:BSU27070" /db_xref="EnsemblGenomes-Tr:CAB14649" /db_xref="GOA:P26379" /db_xref="InterPro:IPR004701" /db_xref="InterPro:IPR013789" /db_xref="InterPro:IPR033887" /db_xref="InterPro:IPR036662" /db_xref="SubtiList:BG10316" /db_xref="UniProtKB/Swiss-Prot:P26379" /translation="MISVIISGHGDFPIALKESSGMIFGEENNLIAVPFFKGEGIQTL QEKYHQALKDIPEEHEVLFLVDIFGGTPYNAAASFIAEDQRMDMAAGVNLPILLEVLS LREHLALKDLLNNLKAMSQQSFQVCSEHLEKVKTANQDTREDEL*" gene complement(2627993..2628433) /gene="levD" /locus_tag="BSU_27070" /old_locus_tag="BSU27070" downshifts 2628430 /Source="Nicolas_upshifts" /id="D1381" /incds=0 /nref=2 /ntot=5 /MaxReadThrough="0.496260000000001" /MaxDrop="4.58461" /score="24.8267602" /energy="-16.3" /TU="NA" /idTUdmin="U2080" /TUdmin=3740 /isTUend="FALSE" misc_feature complement(2628470..2628488) /Source="Nicolas_upshift_promotors" /id="U2081" /multdbtbs="SigL" /comp="M18" /sig="SigL" /pcomp="0.886113886113886" /psig="0.886113886113886" /xcortree=1498 /SigmaFactorBS="ttgctattggctgaaataacaatgaaaacgcttaacacaact gtgtTGGCACGATCCTTGCATTAtatatggatgtacaaaacaggaaaggagcaataga t" /listShort="levD, levE, levF, levG, S1019, sacC" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(2628474) /Source="Nicolas_upshifts" /id="U2081" /multdbtbs="SigL" /comp="M18" /sig="SigL" /pcomp="0.886113886113886" /psig="0.886113886113886" /xcortree=1498 /SigmaFactorBS="ttgctattggctgaaataacaatgaaaacgcttaacacaact gtgtTGGCACGATCCTTGCATTAtatatggatgtacaaaacaggaaaggagcaataga t" /listShort="levD, levE, levF, levG, S1019, sacC" /GFF_Attribute="listLong" CDS complement(2628623..2631430) /gene="levR" /locus_tag="BSU_27080" /old_locus_tag="BSU27080" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:1619665, 1900939, 7592487, 8057358, 9622354, 10589728, 19202299" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1619665, 1900939, 7592487, 8057358, 9622354, 10589728, 19202299; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator (NifA/NtrC family)" /protein_id="NP_390586.2" /db_xref="EnsemblGenomes-Gn:BSU27080" /db_xref="EnsemblGenomes-Tr:CAB14650" /db_xref="GOA:P23914" /db_xref="InterPro:IPR001550" /db_xref="InterPro:IPR002078" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR004701" /db_xref="InterPro:IPR011608" /db_xref="InterPro:IPR025943" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR033887" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="InterPro:IPR036634" /db_xref="InterPro:IPR036662" /db_xref="SubtiList:BG10677" /db_xref="UniProtKB/Swiss-Prot:P23914" /translation="MRRIDKIYHQLKHNFHDSTLDHLLKIQGNSAKEIAEQLKMERSN VSFELNNLVRSKKVIKIKTFPVRYIPVEIAEKLFNKKWDTEMMEVKDLQAFSGNSKQN HQHISTNPLELMIGAKGSLKKAISQAKAAVFYPPNGLHMLLLGPTGSGKSLFANRIYQ FAIYSDILKAGAPFITFNCADYYNNPQLLLSQLFGHKKGSFTGAAEDKAGLVEQANGG ILFMDEIHRLPPEGQEMLFYFIDSGSYNRLGESEHKRTSNVLFICATTENPSSALLKT FLRRIPMTIHIPSLEERSLNERVDLTTFLLGKEAERIKKNLSVHIDVYNALIHSAKFG NVGQLKSNVQLVCAHGFLHNLDRNEVIELTVRDLPDEIKQEWMSSSKNMQRSKAISEY VNITTIISPIVEDETTKIDEDLSFNLYHLIEEKVKTLMKEGLSKKDINQYILTDVHLH VRSFFHHQAFQKDNLLTFVEDDVIQMTKQLKEIAEHELDCTFDRKFIYFLSMHIDAFL KRGKQIDVLNTQETDEIRDTHVKEYRVAMIFKDKIQEYFKVAIPEIEVIYLTMLIHSI KSLKENKRVGIIVAAHGNSTASSMVEVATELLGSTPIAAVDMPLTVSPSDILECVAEK MKQVDEGEGVLMLVDMGSLAMLESRLEEKTGISIKTISNVTTSMVLDAVRKVNYLNLN LHAIYQSVTKDFIELWERQPAASGKKKALVSICTTGSGTAKKLEDILTTIVNKASDTP IHILTVSSIKLANSIKEIEKEYEILATVGTKDPKINAPHVSLEVLIEGEGEKLIQQAI TKGSISLSNGLNEANIIVRELCEDSLKKYLVFLNPHHVIDMLLEWLQTVQDELGVIFN NAVLIKVIMHTAFAFERVIKQNPIAFSEEEEINDQLKEMVYVTERTLAPYEEKLGLRI SDDEKLFIAAIFAEEVHGQLF*" gene complement(2628623..2631430) /gene="levR" /locus_tag="BSU_27080" /old_locus_tag="BSU27080" misc_feature complement(2631646..2631665) /Source="Nicolas_upshift_promotors" /id="U2082" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.743256743256743" /psig="0.957042957042957" /xcortree=2981 /SigmaFactorBS="attcattttttgtcattgattattttgacatcattacattcc ccgagAATGATAAACTGTTTACTGAttattacttttgaaggggactggccctccagaa c" /listShort="levR" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(2631652) /Source="Nicolas_upshifts" /id="U2082" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.743256743256743" /psig="0.957042957042957" /xcortree=2981 /SigmaFactorBS="attcattttttgtcattgattattttgacatcattacattcc ccgagAATGATAAACTGTTTACTGAttattacttttgaaggggactggccctccagaa c" /listShort="levR" /GFF_Attribute="listLong" CDS 2631977..2632117 /locus_tag="BSU_27085" /old_locus_tag="BSU27085" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_009513990.1" /translation="MTFLFYSAIQVESRVKNRATRHVTALKIVLKFKNKSIYSFKCYN IR*" gene 2631977..2632117 /locus_tag="BSU_27085" /old_locus_tag="BSU27085" misc_feature 2632098..2632117 /Source="Nicolas_upshift_promotors" /id="U2083" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.929070929070929" /psig="0.997002997002997" /xcortree=1762 /SigmaFactorBS="agcacttaaaatagttttaaaatttaaaaataaaagtatcta ttcttttaAATGTTATAATATCCGATAAaactttactcatctttttattactggagga a" /listShort="aapA" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 2632108 /Source="Nicolas_upshifts" /id="U2083" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.929070929070929" /psig="0.997002997002997" /xcortree=1762 /SigmaFactorBS="agcacttaaaatagttttaaaatttaaaaataaaagtatcta ttcttttaAATGTTATAATATCCGATAAaactttactcatctttttattactggagga a" /listShort="aapA" /GFF_Attribute="listLong" CDS 2632156..2633544 /gene="aapA" /locus_tag="BSU_27090" /old_locus_tag="BSU27090" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 15849754, 16850406, 17608695, 22084243; Product type t: transporter" /codon_start=1 /transl_table=11 /product="small amino acid permease" /protein_id="NP_390587.2" /db_xref="EnsemblGenomes-Gn:BSU27090" /db_xref="EnsemblGenomes-Tr:CAB14651" /db_xref="GOA:O06005" /db_xref="InterPro:IPR002293" /db_xref="InterPro:IPR004840" /db_xref="InterPro:IPR004841" /db_xref="SubtiList:BG12556" /db_xref="UniProtKB/Swiss-Prot:O06005" /translation="MIGNSSKDNFGQQQKLSRGLKNRHIQLMAIGGAIGTGLFLGSGK SIHFAGPSILFAYLITGVFCFFIMRSLGELLLSNAGYHSFVDFVRDYLGNMAAFITGW TYWFCWISLAMADLTAVGIYTQYWLPDVPQWLPGLLALIILLIMNLATVKLFGELEFW FALIKVIAILALIVTGILLIAKGFSAASGPASLNNLWSHGGMFPNGWHGFILSFQMVV FAFVGIELVGLTAGETENPQKVIPKAINQIPVRILLFYVGALFVIMCIYPWNVLNPNE SPFVQVFSAVGIVVAASLINFVVLTSAASAANSALFSTSRMVYSLAKDHHAPGLLKKL TSSNVPSNALFFSSIAILIGVSLNYLMPEQVFTLITSVSTICFIFIWGITVICHLKYR KTRQHEAKANKFKMPFYPLSNYLTLAFLAFILVILALANDTRIALFVTPVWFVLLIIL YKVQTRRGHKVK*" gene 2632156..2633544 /gene="aapA" /locus_tag="BSU_27090" /old_locus_tag="BSU27090" downshifts 2633533 /Source="Nicolas_upshifts" /id="D1382" /incds=0 /nref=7 /ntot=120 /MaxReadThrough="0.96985" /MaxDrop="3.54068" /score="11.8049306" /energy="-13" /TU="NA" /idTUdmin="U2083" /TUdmin="-21" /isTUend="TRUE" S_feature complement(2633566..2633639) /Source="Nicolas_S_feature" /locus_tag="new_2767968_2768041_c" /HighExp="MG 120, LBGstat, MG 150, MG 90, S0, HPh, HiOs, GM-0.1, aero, GM 5" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="NA" /TUshortPSig="NA" /TUlongSig="NA" /TUlongPSig="NA" /label="S1020" downshifts complement(2633608) /Source="Nicolas_upshifts" /id="D1383" /incds=0 /nref=11 /ntot=121 /MaxReadThrough="1.79954" /MaxDrop="4.59487" /score="37.881034" /energy="-13" /TU="NA" /idTUdmin="U2084" /TUdmin=0 /isTUend="TRUE" CDS complement(2633640..2634272) /gene="yrhP" /locus_tag="BSU_27100" /old_locus_tag="BSU27100" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16098526, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative amino acid exporter" /protein_id="NP_390588.1" /db_xref="EnsemblGenomes-Gn:BSU27100" /db_xref="EnsemblGenomes-Tr:CAB14652" /db_xref="GOA:O05406" /db_xref="InterPro:IPR001123" /db_xref="InterPro:IPR004778" /db_xref="SubtiList:BG12304" /db_xref="UniProtKB/Swiss-Prot:O05406" /translation="MHSLLAYIPIAAMMVIIPGADTMLVMKNTLRYGPKAGRYNILGL ATGLSFWTVIAILGLSVVIAKSVILFTTIKYLGAAYLIYLGVKSFFAKSMFSLDDMQS QAKNMASSPKRYYKTSFMQGSLSNILNPKTVLVYVTIMPQFINLNGNINQQLIILASI LTLLAVLWFLFLVYIIDYAKKWMKNSKFQKVFQKITGIILVGFGIKTGLS*" gene complement(2633640..2634272) /gene="yrhP" /locus_tag="BSU_27100" /old_locus_tag="BSU27100" downshifts complement(2633696) /Source="Nicolas_upshifts" /id="D1384" /incds=0 /nref=4 /ntot=132 /MaxReadThrough="4.46187" /MaxDrop="3.11632" /score="37.881034" /energy="-13" /TU="U2084" /idTUdmin="U2084" /TUdmin="-88" /isTUend="FALSE" promotor_-10 complement(2634326..2634345) /Source="Nicolas_upshift_promotors" /id="U2084" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.717282717282717" /psig=1 /xcortree=2999 /SigmaFactorBS="tgccttagtaatcgctattttaacaaatcaTATTGATTtatt ccaaacgcatTGATACACTTTTATAAGTAGttacttttgtagtcactatatgattgag g" /listShort="yrhP" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2634337) /Source="Nicolas_upshifts" /id="U2084" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.717282717282717" /psig=1 /xcortree=2999 /SigmaFactorBS="tgccttagtaatcgctattttaacaaatcaTATTGATTtatt ccaaacgcatTGATACACTTTTATAAGTAGttacttttgtagtcactatatgattgag g" /listShort="yrhP" /GFF_Attribute="listLong" promotor_-35 2634351..2634357 /Source="Nicolas_upshift_promotors" /id="U2085" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.402597402597403" /psig=1 /xcortree=1861 /SigmaFactorBS="acaaaagtaactacttataaaagtgtatcaatgcgTTTGGAA taaatcaatatgaTTTGTTAAAATAGCGATTACtaaggcagcgattgctctttatatt g" /listShort="yrhO" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 complement(2634360..2634367) /Source="Nicolas_upshift_promotors" /id="U2084" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.717282717282717" /psig=1 /xcortree=2999 /SigmaFactorBS="tgccttagtaatcgctattttaacaaatcaTATTGATTtatt ccaaacgcatTGATACACTTTTATAAGTAGttacttttgtagtcactatatgattgag g" /listShort="yrhP" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2634371..2634390 /Source="Nicolas_upshift_promotors" /id="U2085" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.402597402597403" /psig=1 /xcortree=1861 /SigmaFactorBS="acaaaagtaactacttataaaagtgtatcaatgcgTTTGGAA taaatcaatatgaTTTGTTAAAATAGCGATTACtaaggcagcgattgctctttatatt g" /listShort="yrhO" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2634376 /Source="Nicolas_upshifts" /id="U2085" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.402597402597403" /psig=1 /xcortree=1861 /SigmaFactorBS="acaaaagtaactacttataaaagtgtatcaatgcgTTTGGAA taaatcaatatgaTTTGTTAAAATAGCGATTACtaaggcagcgattgctctttatatt g" /listShort="yrhO" /GFF_Attribute="listLong" CDS 2634425..2635252 /gene="yrhO" /locus_tag="BSU_27110" /old_locus_tag="BSU27110" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative transcriptional regulator controlling amino acid export" /protein_id="NP_390589.1" /db_xref="EnsemblGenomes-Gn:BSU27110" /db_xref="EnsemblGenomes-Tr:CAB14653" /db_xref="InterPro:IPR002831" /db_xref="InterPro:IPR021586" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG12303" /db_xref="UniProtKB/Swiss-Prot:O05405" /translation="MKENMLDILKNLNFTEYESKAYLALLQESPLTGYAVAKKSGVPR SKIYEVLESLVIRGDVFVSHGNTPQYVPVPAKELIKNRRLKAEEHFDQAEKYFEKFEQ TANDRENIWNITGRSEILEKVKACILSAKKRILLEIWKEDFKEIEAELKQAAEQGVIV TIIAYGDIVSDFANVYLHDMSSEITEEYDGRWLVYSGDDSEVVAGIVSLGNDSRAAWT MHVGLVMPITEVIIHDLYLMEILKKHRELLEESFGKNLIQLRRKFSIHSDFKKHYLE* " gene 2634425..2635252 /gene="yrhO" /locus_tag="BSU_27110" /old_locus_tag="BSU27110" downshifts 2635248 /Source="Nicolas_upshifts" /id="D1385" /incds=0 /nref=57 /ntot=233 /MaxReadThrough="0.74814" /MaxDrop="5.12635" /score="6.64108595" /energy="-9.5" /TU="NA" /idTUdmin="U2085" /TUdmin=0 /isTUend="TRUE" promotor_-35 2635365..2635374 /Source="Nicolas_upshift_promotors" /id="U2086" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp="0.874125874125874" /psig="0.874125874125874" /xcortree=1440 /SigmaFactorBS="tttacttctctcttttaaaaaatgtgattctgcGCAAACTAT TtttcagcctgccGCGTCTATCCTAGGTAacagcctacgatatacgtatattcaaaaa g" /listShort="sigV" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2635387..2635402 /Source="Nicolas_upshift_promotors" /id="U2086" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp="0.874125874125874" /psig="0.874125874125874" /xcortree=1440 /SigmaFactorBS="tttacttctctcttttaaaaaatgtgattctgcGCAAACTAT TtttcagcctgccGCGTCTATCCTAGGTAacagcctacgatatacgtatattcaaaaa g" /listShort="sigV" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2635392 /Source="Nicolas_upshifts" /id="U2086" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp="0.874125874125874" /psig="0.874125874125874" /xcortree=1440 /SigmaFactorBS="tttacttctctcttttaaaaaatgtgattctgcGCAAACTAT TtttcagcctgccGCGTCTATCCTAGGTAacagcctacgatatacgtatattcaaaaa g" /listShort="sigV" /GFF_Attribute="listLong" CDS 2635448..2635948 /gene="sigV" /locus_tag="BSU_27120" /old_locus_tag="BSU27120" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:16274938, 21926231, 23687273, 26901131" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16274938, 21926231, 23687273, 26901131; Product type r: regulator" /codon_start=1 /transl_table=11 /product="RNA polymerase ECF(extracytoplasmic function)-type sigma factor (sigma(V))" /protein_id="NP_390590.1" /db_xref="EnsemblGenomes-Gn:BSU27120" /db_xref="EnsemblGenomes-Tr:CAB14654" /db_xref="GOA:O05404" /db_xref="InterPro:IPR000838" /db_xref="InterPro:IPR007627" /db_xref="InterPro:IPR013249" /db_xref="InterPro:IPR013324" /db_xref="InterPro:IPR013325" /db_xref="InterPro:IPR014284" /db_xref="InterPro:IPR036388" /db_xref="SubtiList:BG11974" /db_xref="UniProtKB/Swiss-Prot:O05404" /translation="MKKKQTTKALLVTCITDHKQDFYRLAFSYVKNQDDALDIVQESI KKALSSVETVRNPETIKSWFYKILVRTAIDFLRKQKKIRVMDDETIEFLSKGKEDHYK DTDLHEALDELPYRYKTIIILRFFEDLKLEEIAEITGENTNTVKTRLYRALKLMRIQL TKEDLS*" gene 2635448..2635948 /gene="sigV" /locus_tag="BSU_27120" /old_locus_tag="BSU27120" CDS 2635948..2636805 /gene="rsiV" /locus_tag="BSU_27130" /old_locus_tag="BSU27130" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:16274938, 23687273, 26901131" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16274938, 23687273, 26901131; Product type r: regulator" /codon_start=1 /transl_table=11 /product="anti-sigma(V) factor" /protein_id="NP_390591.1" /db_xref="EnsemblGenomes-Gn:BSU27130" /db_xref="EnsemblGenomes-Tr:CAB14655" /db_xref="GOA:O05403" /db_xref="InterPro:IPR021729" /db_xref="InterPro:IPR025303" /db_xref="InterPro:IPR037126" /db_xref="PDB:5JEN" /db_xref="SubtiList:BG12302" /db_xref="UniProtKB/Swiss-Prot:O05403" /translation="MDKRLQQLREEYKNVQIPKELDIIVEKALQQEPKKKRIVMWPTS AAIAAAILFTALVNINPDAAQAMSKIPVIGKIVKAITFIEIKEEKDQSSIDVKTPALS GLSNKELENSINEKYLKESQQLYKEFIQSTSKNKKGHLSIYSDYETVTDTPDLLSIRR NIETTQASSYTQSRYITIDKKNDILLTLKSLFKDERYIKVISQNIKEQMKQQMKEDPN KIYWLTDEDAEPFKTILPDQTFYITEDHKLVISFDEYEVAPGYMGVTEFTIPTGVISN LLVGERYIR*" gene 2635948..2636805 /gene="rsiV" /locus_tag="BSU_27130" /old_locus_tag="BSU27130" promotor_-10 complement(2636823..2636834) /Source="Nicolas_upshift_promotors" /id="U2087" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.784215784215784" /psig="0.784215784215784" /xcortree=1210 /SigmaFactorBS="atagtatgcaaatattctcgttgtttttgatagcggggttac gacctCGAATAGagaagagagaaaacATCCATAATCTTagatggatgtttttatttta t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2636842) /Source="Nicolas_upshifts" /id="U2087" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.784215784215784" /psig="0.784215784215784" /xcortree=1210 /SigmaFactorBS="atagtatgcaaatattctcgttgtttttgatagcggggttac gacctCGAATAGagaagagagaaaacATCCATAATCTTagatggatgtttttatttta t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(2636849..2636855) /Source="Nicolas_upshift_promotors" /id="U2087" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.784215784215784" /psig="0.784215784215784" /xcortree=1210 /SigmaFactorBS="atagtatgcaaatattctcgttgtttttgatagcggggttac gacctCGAATAGagaagagagaaaacATCCATAATCTTagatggatgtttttatttta t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" CDS 2636916..2638820 /gene="oatA" /locus_tag="BSU_27140" /old_locus_tag="BSU27140" /EC_number="2.3.1.-" /function="16.8: Protect" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:1521192, 15661003, 21135105, 21586574, 21856855, 21926231" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1521192, 15661003, 21135105, 21586574, 21856855, 21926231; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="peptidoglycan O-acetyltransferase" /protein_id="NP_390592.1" /db_xref="EnsemblGenomes-Gn:BSU27140" /db_xref="EnsemblGenomes-Tr:CAB14656" /db_xref="GOA:O05402" /db_xref="InterPro:IPR002656" /db_xref="InterPro:IPR036514" /db_xref="SubtiList:BG12301" /db_xref="UniProtKB/Swiss-Prot:O05402" /translation="MYHKTQHHRYIPGLDGLRAFAVLSVITYHLNFNWANGGFIGVDI FFVLSGYLITSILLPAYGNDINLDFRDFWVRRIRRLLPAAYLMIFSTVVWVVLFDREL LHTVRGDAISSLFYMSNWWFIFHKLSYFDSFGSPSPLKNLWSLAIEEQFYIIWPMFLV VGMYIMKSRARLAAVISLLVLCSAVMMSVLYEPGGDPSRVYYGTDTRSFELLIGCALA LVWPMKRLSSNRLPSKLKHTLHATEFLAFCILVLCVYFTDEYEPFLYRGGMLFISVTA AILIACVCHPSSFLGNLLSWRPLRWLGTRSYGIYLWHYPVIVLSTPVQEIGNPVFWHI VLKVIVTCILAELSYHFIEKPIRTQGFRSFSRRVFIHRIKEWKTTSVISKMSIGFIIF AILIFAGGLSGLAGEQKHPTKWTYSSQETNADTSQASGDKKNAAADKKHNPEQKTTDS NQGQKENKDSGQETHKKKDTQSQQLKKPADTAKEVLAIGDSVMLDISSHLRQSFSNVT IDGKVGRQMSQALELAREYKSFNQPNKAVIIELGTNGYFTNSQIEQLLQSFSKAHIYL VNTRVPRQWESKVNESLQQQAHAHQNVTLVDWHTEALQHPEYFTPDGVHLVPKGAKTL TALIVQAMKS*" gene 2636916..2638820 /gene="oatA" /locus_tag="BSU_27140" /old_locus_tag="BSU27140" promotor_-35 2638901..2638907 /Source="Nicolas_upshift_promotors" /id="U2088" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=182 /SigmaFactorBS="gattatgtcttctttcagcaaggcagcccttaTGTTTACatg ccgtttacgtaaGGGTAAGCCAAAATTGAATggagggatgataatgaaaggaaatgaa g" /listShort="yrhK, S1021, S1022" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2638923..2638941 /Source="Nicolas_upshift_promotors" /id="U2088" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=182 /SigmaFactorBS="gattatgtcttctttcagcaaggcagcccttaTGTTTACatg ccgtttacgtaaGGGTAAGCCAAAATTGAATggagggatgataatgaaaggaaatgaa g" /listShort="yrhK, S1021, S1022" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2638929 /Source="Nicolas_upshifts" /id="U2088" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=182 /SigmaFactorBS="gattatgtcttctttcagcaaggcagcccttaTGTTTACatg ccgtttacgtaaGGGTAAGCCAAAATTGAATggagggatgataatgaaaggaaatgaa g" /listShort="yrhK, S1021, S1022" /GFF_Attribute="listLong" CDS 2638954..2639244 /gene="yrhK" /locus_tag="BSU_27150" /old_locus_tag="BSU27150" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 21926231" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_390593.1" /db_xref="EnsemblGenomes-Gn:BSU27150" /db_xref="EnsemblGenomes-Tr:CAB14657" /db_xref="GOA:O05401" /db_xref="InterPro:IPR025424" /db_xref="SubtiList:BG12300" /db_xref="UniProtKB/Swiss-Prot:O05401" /translation="MKGNEEHDIQKELKRYELFFKKRYKVLYTVNDFIIGAMFLVGSF FFFYDRLMSAGIWLFAIGSLLLLIRPTIRLIHDFHYRKHVEQQFKHQSSTDD*" gene 2638954..2639244 /gene="yrhK" /locus_tag="BSU_27150" /old_locus_tag="BSU27150" S_feature 2639245..2639360 /Source="Nicolas_S_feature" /locus_tag="new_2773647_2773762" /HighExp="Etha, Salt, LPhT, HiTm, G135, LBGstat, G180, G150, Heat, H2O2" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigB" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S1021" promotor_-35 2639342..2639349 /Source="Nicolas_upshift_promotors" /id="U2089" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=79 /SigmaFactorBS="gactttcagactatttatttttaaaaacaaggtaaaaagaAC TAAACTtttgcctctgcatGCCGATATGAATAATAAGGccggcgcgatactccctata a" /listShort="S1022" /GFF_Attribute="listLong" /label="promotor_-35" S_feature 2639362..2639487 /Source="Nicolas_S_feature" /locus_tag="new_2773764_2773889" /HighExp="Gly, G/S, Lbstat, C90, Pyr, LPhT, LoTm, Etha, T0.30H, C30" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigD, SigB" /TUshortPSig="0.998, 0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S1022" upshifts 2639362 /Source="Nicolas_upshifts" /id="U2089" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=79 /SigmaFactorBS="gactttcagactatttatttttaaaaacaaggtaaaaagaAC TAAACTtttgcctctgcatGCCGATATGAATAATAAGGccggcgcgatactccctata a" /listShort="S1022" /GFF_Attribute="listLong" promotor_-10 2639363..2639381 /Source="Nicolas_upshift_promotors" /id="U2089" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=79 /SigmaFactorBS="gactttcagactatttatttttaaaaacaaggtaaaaagaAC TAAACTtttgcctctgcatGCCGATATGAATAATAAGGccggcgcgatactccctata a" /listShort="S1022" /GFF_Attribute="listLong" /label="promotor_-10" misc_RNA 2639381..2639481 /gene="surF" /locus_tag="BSU_misc_RNA_82" /product="small untranslated RNA expressed under sporulation conditions (SurF-AbrB)" /experiment="publication(s) with functional evidences, PMID:20709900, 25790031" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 20709900, 25790031; Product type n: RNA" gene 2639381..2639481 /gene="surF" /locus_tag="BSU_misc_RNA_82" downshifts 2639444 /Source="Nicolas_upshifts" /id="D1386" /incds=0 /nref=7 /ntot=129 /MaxReadThrough="3.60641" /MaxDrop="5.24336" /score="25.0079309" /energy="-15.8" /TU="U2089" /idTUdmin="U2088" /TUdmin=16 /isTUend="TRUE" CDS complement(2639488..2642652) /gene="cypB" /locus_tag="BSU_27160" /old_locus_tag="BSU27160" /EC_number="1.14.14.1" /function="16.8: Protect" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:11574077, 12775685" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11574077, 12775685; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="cytochrome P450 CYP102A3" /protein_id="NP_390594.1" /db_xref="EnsemblGenomes-Gn:BSU27160" /db_xref="EnsemblGenomes-Tr:CAB14658" /db_xref="GOA:O08336" /db_xref="InterPro:IPR001094" /db_xref="InterPro:IPR001128" /db_xref="InterPro:IPR001433" /db_xref="InterPro:IPR001709" /db_xref="InterPro:IPR003097" /db_xref="InterPro:IPR008254" /db_xref="InterPro:IPR017927" /db_xref="InterPro:IPR017938" /db_xref="InterPro:IPR017972" /db_xref="InterPro:IPR023206" /db_xref="InterPro:IPR029039" /db_xref="InterPro:IPR036396" /db_xref="SubtiList:BG12299" /db_xref="UniProtKB/Swiss-Prot:O08336" /translation="MKQASAIPQPKTYGPLKNLPHLEKEQLSQSLWRIADELGPIFRF DFPGVSSVFVSGHNLVAEVCDEKRFDKNLGKGLQKVREFGGDGLFTSWTHEPNWQKAH RILLPSFSQKAMKGYHSMMLDIATQLIQKWSRLNPNEEIDVADDMTRLTLDTIGLCGF NYRFNSFYRDSQHPFITSMLRALKEAMNQSKRLGLQDKMMVKTKLQFQKDIEVMNSLV DRMIAERKANPDENIKDLLSLMLYAKDPVTGETLDDENIRYQIITFLIAGHETTSGLL SFAIYCLLTHPEKLKKAQEEADRVLTDDTPEYKQIQQLKYIRMVLNETLRLYPTAPAF SLYAKEDTVLGGEYPISKGQPVTVLIPKLHRDQNAWGPDAEDFRPERFEDPSSIPHHA YKPFGNGQRACIGMQFALQEATMVLGLVLKHFELINHTGYELKIKEALTIKPDDFKIT VKPRKTAAINVQRKEQADIKAETKPKETKPKHGTPLLVLFGSNLGTAEGIAGELAAQG RQMGFTAETAPLDDYIGKLPEEGAVVIVTASYNGAPPDNAAGFVEWLKELEEGQLKGV SYAVFGCGNRSWASTYQRIPRLIDDMMKAKGASRLTAIGEGDAADDFESHRESWENRF WKETMDAFDINEIAQKEDRPSLSITFLSEATETPVAKAYGAFEGIVLENRELQTAAST RSTRHIELEIPAGKTYKEGDHIGILPKNSRELVQRVLSRFGLQSNHVIKVSGSAHMAH LPMDRPIKVVDLLSSYVELQEPASRLQLRELASYTVCPPHQKELEQLVSDDGIYKEQV LAKRLTMLDFLEDYPACEMPFERFLALLPSLKPRYYSISSSPKVHANIVSMTVGVVKA SAWSGRGEYRGVASNYLAELNTGDAAACFIRTPQSGFQMPNDPETPMIMVGPGTGIAP FRGFIQARSVLKKEGSTLGEALLYFGCRRPDHDDLYREELDQAEQDGLVTIRRCYSRV ENEPKGYVQHLLKQDTQKLMTLIEKGAHIYVCGDGSQMAPDVERTLRLAYEAEKAASQ EESAVWLQKLQDQRRYVKDVWTGM*" gene complement(2639488..2642652) /gene="cypB" /locus_tag="BSU_27160" /old_locus_tag="BSU27160" downshifts complement(2639504) /Source="Nicolas_upshifts" /id="D1387" /incds=0 /nref=25 /ntot=213 /MaxReadThrough="2.3596" /MaxDrop="4.0425" /score="-9.99429269" /energy="-17.6" /TU="NA" /idTUdmin="U2091" /TUdmin=0 /isTUend="TRUE" promotor_-35 2640638..2640647 /Source="Nicolas_upshift_promotors" /id="U2090" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1249 /SigmaFactorBS="ctggagttctcgattcTCTAACACAAtcccttcaaacgcGCC ATATGCTTTAGCAACCGgcgtttccgtcgcttcactgagaaaagtaatcgataatgaa g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2640661..2640680 /Source="Nicolas_upshift_promotors" /id="U2090" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1249 /SigmaFactorBS="ctggagttctcgattcTCTAACACAAtcccttcaaacgcGCC ATATGCTTTAGCAACCGgcgtttccgtcgcttcactgagaaaagtaatcgataatgaa g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2640682 /Source="Nicolas_upshifts" /id="U2090" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1249 /SigmaFactorBS="ctggagttctcgattcTCTAACACAAtcccttcaaacgcGCC ATATGCTTTAGCAACCGgcgtttccgtcgcttcactgagaaaagtaatcgataatgaa g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" CDS complement(2642668..2643252) /gene="bscR" /locus_tag="BSU_27170" /old_locus_tag="BSU27170" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:11574077" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11574077; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator for cypB" /protein_id="NP_390595.1" /db_xref="EnsemblGenomes-Gn:BSU27170" /db_xref="EnsemblGenomes-Tr:CAB14659" /db_xref="GOA:O08335" /db_xref="InterPro:IPR001647" /db_xref="InterPro:IPR009057" /db_xref="InterPro:IPR023772" /db_xref="InterPro:IPR032551" /db_xref="SubtiList:BG12298" /db_xref="UniProtKB/Swiss-Prot:O08335" /translation="MISASSSKYDMIMKASVSLFTERGFDATTIPMIAERAHVGTGTI YRYFDSKETLVNVLFQESIQRFTEKLKQDVSELPVREGFHHVFCCLVQFTKESDYALF FLETKKDAHYLNHTSKKMIENLTQMLDDYFNKGKAEGVIRSLPSNVLIAIVLGAFLKI YQLVQTGDIEMDTDLITELEQCCWDAIKLHSSQK*" gene complement(2642668..2643252) /gene="bscR" /locus_tag="BSU_27170" /old_locus_tag="BSU27170" CDS complement(2643475..2644017) /gene="yrhH" /locus_tag="BSU_27180" /old_locus_tag="BSU27180" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15870467; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative methyltransferase" /protein_id="NP_390596.1" /db_xref="EnsemblGenomes-Gn:BSU27180" /db_xref="EnsemblGenomes-Tr:CAB14660" /db_xref="GOA:O05400" /db_xref="InterPro:IPR013216" /db_xref="InterPro:IPR029063" /db_xref="SubtiList:BG12297" /db_xref="UniProtKB/Swiss-Prot:O05400" /translation="MLENRLYKRSDFWKLFSRKYKLTKTIEHMMIDSIDIQENDRILE IGIGNGTVFKSITKKLKKGSLKSIDPSKRKVRQISRANRKNMGNGEVFHGYPEDIPFD DRTFNKVFSLHTVQSCTDIRLALREIYRVLQIDGRFYISIDTNTGEKEKTYIQLLKDQ HFRDLSVIRRASCLCIVAVK*" gene complement(2643475..2644017) /gene="yrhH" /locus_tag="BSU_27180" /old_locus_tag="BSU27180" S_feature complement(2644018..2644103) /Source="Nicolas_S_feature" /locus_tag="new_2778420_2778505_c" /HighExp="T-0.40H, Salt, T0.30H, Heat, T0.0H, Etha, T-1.10H, T-1.40H, T1.0H, T1.30H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigWXY, SigA" /TUshortPSig="1, 0.998" /TUlongSig="SigA, SigA" /TUlongPSig="1, 1" /label="S1023" promotor_-10 complement(2644101..2644116) /Source="Nicolas_upshift_promotors" /id="U2091" /multdbtbs="SigW,SigX" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1647 /SigmaFactorBS="aaaaaatgaaaaagtttagttctatTGAAACATTTttcaata cattgCCGTCTAGTTGGTACCttccttcacttttagaaatgaagatgatgtttatttt t" /listShort="S1023, yrhH, bscR, cypB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2644103) /Source="Nicolas_upshifts" /id="U2091" /multdbtbs="SigW,SigX" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1647 /SigmaFactorBS="aaaaaatgaaaaagtttagttctatTGAAACATTTttcaata cattgCCGTCTAGTTGGTACCttccttcacttttagaaatgaagatgatgtttatttt t" /listShort="S1023, yrhH, bscR, cypB" /GFF_Attribute="listLong" promotor_-35 complement(2644129..2644138) /Source="Nicolas_upshift_promotors" /id="U2091" /multdbtbs="SigW,SigX" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1647 /SigmaFactorBS="aaaaaatgaaaaagtttagttctatTGAAACATTTttcaata cattgCCGTCTAGTTGGTACCttccttcacttttagaaatgaagatgatgtttatttt t" /listShort="S1023, yrhH, bscR, cypB" /GFF_Attribute="listLong" /label="promotor_-35" S_feature complement(2644172..2644388) /Source="Nicolas_S_feature" /locus_tag="new_2778574_2778790_c" /HighExp="S7, S8, S6, LPhT, BT, LBGstat, S5, B36, G/S, Cold" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.99909999999999999" /TUshortSig="SigK, SigA" /TUshortPSig="0.999, 0.998" /TUlongSig="SigA, SigA" /TUlongPSig="1, 1" /label="S1024" CDS complement(2644206..2644364) /locus_tag="BSU_27185" /old_locus_tag="BSU27185" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_009513991.1" /translation="MMNDYQKRLPSIGHGYASMPHSFKHGYGNPFRQQRLMAMQQQRL YVFPYHWH*" gene complement(2644206..2644364) /locus_tag="BSU_27185" /old_locus_tag="BSU27185" downshifts complement(2644215) /Source="Nicolas_upshifts" /id="D1388" /incds=0 /nref=34 /ntot=184 /MaxReadThrough="3.04168" /MaxDrop="7.65849" /score="23.6695072" /energy="-11.3" /TU="U2093" /idTUdmin="U2092" /TUdmin="-3" /isTUend="TRUE" promotor_-10 complement(2644386..2644405) /Source="Nicolas_upshift_promotors" /id="U2092" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1229 /SigmaFactorBS="aaggaccaagtttagcgaaaTAGCTGTCAAgaaaatgcgcgc cTGCATATAGTAAATCAACGTtattgtgaggcaggtgatggcatgatgaacgattatc a" /listShort="S1024" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2644388) /Source="Nicolas_upshifts" /id="U2092" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1229 /SigmaFactorBS="aaggaccaagtttagcgaaaTAGCTGTCAAgaaaatgcgcgc cTGCATATAGTAAATCAACGTtattgtgaggcaggtgatggcatgatgaacgattatc a" /listShort="S1024" /GFF_Attribute="listLong" S_feature complement(2644390..2644520) /Source="Nicolas_S_feature" /locus_tag="new_2778792_2778922_c" /HighExp="S7, S8, LPhT, S6, LBGstat, B36, BT, S5, Cold, T-1.10H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.893648" /TUshortSig="SigA, SigA" /TUshortPSig="0.998, 1" /TUlongSig="SigA" /TUlongPSig=1 /label="S1025" promotor_-35 complement(2644419..2644428) /Source="Nicolas_upshift_promotors" /id="U2092" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1229 /SigmaFactorBS="aaggaccaagtttagcgaaaTAGCTGTCAAgaaaatgcgcgc cTGCATATAGTAAATCAACGTtattgtgaggcaggtgatggcatgatgaacgattatc a" /listShort="S1024" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2644521..2644670) /gene="yrzI" /locus_tag="BSU_27190" /old_locus_tag="BSU27190" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_390597.1" /db_xref="EnsemblGenomes-Gn:BSU27190" /db_xref="EnsemblGenomes-Tr:CAB14661" /db_xref="InterPro:IPR012655" /db_xref="SubtiList:BG13819" /db_xref="UniProtKB/Swiss-Prot:O32027" /translation="MTINLFFLTLTIKKRFKSLEEFEREQQIEQIYDEMKESQLKHLY LTNWR*" gene complement(2644521..2644670) /gene="yrzI" /locus_tag="BSU_27190" /old_locus_tag="BSU27190" downshifts 2644664 /Source="Nicolas_upshifts" /id="D1389" /incds=0 /nref=4 /ntot=35 /MaxReadThrough="1.96539" /MaxDrop="3.70444" /score="-6.5827622" /energy="-7.8" /TU="NA" /idTUdmin="U2089" /TUdmin=4972 /isTUend="FALSE" S_feature complement(2644671..2644761) /Source="Nicolas_S_feature" /locus_tag="new_2779073_2779163_c" /HighExp="S7, LBGstat, Cold, S6, B36, LPhT, T-0.40H, LoTm, S8, BT" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="0.998, 1" /TUlongSig="SigA" /TUlongPSig=1 /label="S1026" S_feature complement(2644763..2644982) /Source="Nicolas_S_feature" /locus_tag="new_2779165_2779384_c" /HighExp="B60, B36, S7, BT, LBGstat, Cold, LoTm, LPhT, S6, Pyr" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.52109300000000003" /TUshortSig="SigA, SigA" /TUshortPSig="0.998, 1" /TUlongSig="SigA" /TUlongPSig=1 /label="S1027" downshifts complement(2644806) /Source="Nicolas_upshifts" /id="D1390" /incds=0 /nref=2 /ntot=37 /MaxReadThrough="7.23426" /MaxDrop="3.6023" /score="11.9275075" /energy="-19.6" /TU="U2093,U2094" /idTUdmin="U2094" /TUdmin="-440" /isTUend="FALSE" downshifts 2644928 /Source="Nicolas_upshifts" /id="D1391" /incds=0 /nref=16 /ntot=94 /MaxReadThrough="0.94778" /MaxDrop="4.28987" /score="-6.5827622" /energy="-7.8" /TU="NA" /idTUdmin="U2089" /TUdmin=5236 /isTUend="FALSE" promotor_-10 complement(2644961..2644980) /Source="Nicolas_upshift_promotors" /id="U2093" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.984015984015984" /psig="0.998001998001998" /xcortree=590 /SigmaFactorBS="tcgatgatttgcacaatttccgtccatttttagaaaaagaTG TTTACAaaatggaatttggtGGATATACTTACAAAGTAAGaaaaaagcaaaggaggct g" /listShort="S1027, S1026, yrzI, S1025, S1024, S1023, yrhH" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2644982) /Source="Nicolas_upshifts" /id="U2093" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.984015984015984" /psig="0.998001998001998" /xcortree=590 /SigmaFactorBS="tcgatgatttgcacaatttccgtccatttttagaaaaagaTG TTTACAaaatggaatttggtGGATATACTTACAAAGTAAGaaaaaagcaaaggaggct g" /listShort="S1027, S1026, yrzI, S1025, S1024, S1023, yrhH" /GFF_Attribute="listLong" S_feature complement(2644984..2645059) /Source="Nicolas_S_feature" /locus_tag="new_2779386_2779461_c" /HighExp="Lbexp, dia0, dia5, G150, Cold, C30, Mt0, LBGexp, dia15, Etha" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.115567" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="SigA" /TUlongPSig=1 /label="S1028" promotor_-35 complement(2644995..2645002) /Source="Nicolas_upshift_promotors" /id="U2093" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.984015984015984" /psig="0.998001998001998" /xcortree=590 /SigmaFactorBS="tcgatgatttgcacaatttccgtccatttttagaaaaagaTG TTTACAaaatggaatttggtGGATATACTTACAAAGTAAGaaaaaagcaaaggaggct g" /listShort="S1027, S1026, yrzI, S1025, S1024, S1023, yrhH" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2645060..2645860) /gene="yrhG" /locus_tag="BSU_27200" /old_locus_tag="BSU27200" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406, 24887098; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative formate/nitrite transporter" /protein_id="NP_390598.1" /db_xref="EnsemblGenomes-Gn:BSU27200" /db_xref="EnsemblGenomes-Tr:CAB14662" /db_xref="GOA:O05399" /db_xref="InterPro:IPR000292" /db_xref="InterPro:IPR023271" /db_xref="InterPro:IPR024002" /db_xref="SubtiList:BG12296" /db_xref="UniProtKB/Swiss-Prot:O05399" /translation="MAFRKPDEIAEAAIEAGMKKIKLPLPSLLVLGFLGGAFIALGYL LDIRVIGDLPKEWGSLSSLIGAAVFPVGLILVVLAGAELITGNMMSVAMALFSRKISV KELAINWGIVTIMNLIGALFVAYFFGHLVGLTETGPYLEKTIAVAQGKLDMSFGKVLI SAIGCNWLVCLAVWLSFGAQDAAGKILGIWFPIMAFVAIGFQHVVANMFVIPAAIFAG SFTWGQFIGNIIPAFIGNVIGGAVFVGLIYFIAYHKKDRSRKEMKQVS*" gene complement(2645060..2645860) /gene="yrhG" /locus_tag="BSU_27200" /old_locus_tag="BSU27200" S_feature complement(2645929..2646082) /Source="Nicolas_S_feature" /locus_tag="new_2780331_2780484_c" /HighExp="Lbexp, dia0, dia5, Cold, G150, Etha, HiOs, Salt, C90, dia15" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="1, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S1029" downshifts complement(2645972) /Source="Nicolas_upshifts" /id="D1392" /incds=0 /nref=1 /ntot=70 /MaxReadThrough="6.01922" /MaxDrop="3.7673" /score="23.461824" /energy="-25" /TU="U2094,U2095" /idTUdmin="U2095" /TUdmin="-132" /isTUend="FALSE" promotor_-10 complement(2646073..2646092) /Source="Nicolas_upshift_promotors" /id="U2094" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.418581418581419" /psig=1 /xcortree=111 /SigmaFactorBS="aagaagctctgcaaagctagtatatttgtCATTGACacaaat ttgtcacaTTTGATATGATGTTGCTACAgttatagaaggctaaagcaatggaatgtat g" /listShort="S1029, yrhG, S1028, S1027, S1026, yrzI, S1025" /listLong="S1024, S1023, yrhH" /label="promotor_-10" upshifts complement(2646082) /Source="Nicolas_upshifts" /id="U2094" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.418581418581419" /psig=1 /xcortree=111 /SigmaFactorBS="aagaagctctgcaaagctagtatatttgtCATTGACacaaat ttgtcacaTTTGATATGATGTTGCTACAgttatagaaggctaaagcaatggaatgtat g" /listShort="S1029, yrhG, S1028, S1027, S1026, yrzI, S1025" /listLong="S1024, S1023, yrhH" promotor_-35 complement(2646107..2646113) /Source="Nicolas_upshift_promotors" /id="U2094" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.418581418581419" /psig=1 /xcortree=111 /SigmaFactorBS="aagaagctctgcaaagctagtatatttgtCATTGACacaaat ttgtcacaTTTGATATGATGTTGCTACAgttatagaaggctaaagcaatggaatgtat g" /listShort="S1029, yrhG, S1028, S1027, S1026, yrzI, S1025" /listLong="S1024, S1023, yrhH" /label="promotor_-35" CDS complement(2646123..2646491) /gene="yrhF" /locus_tag="BSU_27210" /old_locus_tag="BSU27210" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_390599.1" /db_xref="EnsemblGenomes-Gn:BSU27210" /db_xref="EnsemblGenomes-Tr:CAB14663" /db_xref="InterPro:IPR018745" /db_xref="SubtiList:BG12295" /db_xref="UniProtKB/Swiss-Prot:O05398" /translation="MSKKIHEFNDIIRKLRKELFGKGPERIHTVFVENMAVSTLYGNL SASEQFIARTPEGREMVHAARTSLIQDLYSKQTPEGMEELMGAKLVHLFSDIKIEENI AVSVFVFDRKIDEQKEALQS*" gene complement(2646123..2646491) /gene="yrhF" /locus_tag="BSU_27210" /old_locus_tag="BSU27210" S_feature complement(2646492..2646588) /Source="Nicolas_S_feature" /locus_tag="new_2780894_2780990_c" /HighExp="T0.30H, LBGstat, T1.0H, T1.30H, G150, Lbexp, dia0, G180, M9-stat, LBGtran" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1030" promotor_-10 complement(2646574..2646593) /Source="Nicolas_upshift_promotors" /id="U2095" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.908091908091908" /psig=1 /xcortree=2748 /SigmaFactorBS="atagactcataacaagatcctattacaaatccatcaacactG CTTTtattataatgtgataTTTATTATAATACAATATGGcaggaaaattttaaccaag t" /listShort="S1030, yrhF, S1029" /listLong="yrhG, S1028, S1027, S1026, yrzI, S1025, S1024, S1023, yrhH" /label="promotor_-10" promotor_-35 2646578..2646581 /Source="Nicolas_upshift_promotors" /id="U2096" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.412587412587413" /psig=1 /xcortree=2755 /SigmaFactorBS="ccctcaggacatttcacttggttaaaattttcctgccatATT GtattataataaatatCACATTATAATAAAAGCAGTgttgatggatttgtaataggat c" /listShort="S1031, yrhE, yrhD" /GFF_Attribute="listLong" /label="promotor_-35" upshifts complement(2646594) /Source="Nicolas_upshifts" /id="U2095" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.908091908091908" /psig=1 /xcortree=2748 /SigmaFactorBS="atagactcataacaagatcctattacaaatccatcaacactG CTTTtattataatgtgataTTTATTATAATACAATATGGcaggaaaattttaaccaag t" /listShort="S1030, yrhF, S1029" /listLong="yrhG, S1028, S1027, S1026, yrzI, S1025, S1024, S1023, yrhH" promotor_-10 2646597..2646616 /Source="Nicolas_upshift_promotors" /id="U2096" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.412587412587413" /psig=1 /xcortree=2755 /SigmaFactorBS="ccctcaggacatttcacttggttaaaattttcctgccatATT GtattataataaatatCACATTATAATAAAAGCAGTgttgatggatttgtaataggat c" /listShort="S1031, yrhE, yrhD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2646599 /Source="Nicolas_upshifts" /id="U2096" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.412587412587413" /psig=1 /xcortree=2755 /SigmaFactorBS="ccctcaggacatttcacttggttaaaattttcctgccatATT GtattataataaatatCACATTATAATAAAAGCAGTgttgatggatttgtaataggat c" /listShort="S1031, yrhE, yrhD" /GFF_Attribute="listLong" S_feature 2646600..2646806 /Source="Nicolas_S_feature" /locus_tag="new_2781002_2781208" /HighExp="G150, Lbexp, dia0, Cold, dia5, G135, LBGstat, LBGexp, G180, C30" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1031" promotor_-35 complement(2646609..2646613) /Source="Nicolas_upshift_promotors" /id="U2095" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.908091908091908" /psig=1 /xcortree=2748 /SigmaFactorBS="atagactcataacaagatcctattacaaatccatcaacactG CTTTtattataatgtgataTTTATTATAATACAATATGGcaggaaaattttaaccaag t" /listShort="S1030, yrhF, S1029" /listLong="yrhG, S1028, S1027, S1026, yrzI, S1025, S1024, S1023, yrhH" /label="promotor_-35" CDS 2646807..2649749 /gene="yrhE" /locus_tag="BSU_27220" /old_locus_tag="BSU27220" /EC_number="1.17.1.9" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 10913079, 19114526; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative formate dehydrogenase" /protein_id="NP_390600.1" /db_xref="EnsemblGenomes-Gn:BSU27220" /db_xref="EnsemblGenomes-Tr:CAB14664" /db_xref="GOA:Q795Y4" /db_xref="InterPro:IPR001041" /db_xref="InterPro:IPR006478" /db_xref="InterPro:IPR006656" /db_xref="InterPro:IPR006657" /db_xref="InterPro:IPR006963" /db_xref="InterPro:IPR009010" /db_xref="InterPro:IPR009051" /db_xref="InterPro:IPR012675" /db_xref="InterPro:IPR017896" /db_xref="InterPro:IPR017900" /db_xref="InterPro:IPR019574" /db_xref="InterPro:IPR036010" /db_xref="SubtiList:BG12294" /db_xref="UniProtKB/Swiss-Prot:Q795Y4" /translation="MMDVKSISVRVDGTEIQARAGATILDILNENGIEYPQICHVPEV DPIQTCDTCIVEANGKLVRSCATVAENGMSIDLSGNRVKEAQTEAMDRLLENHLLYCT VCDNNNGNCTLHNTAEMMGIEHQKYPYTPKEDPSCAVDMSHPFYRYDPNQCIACGQCV EVCQNLQVNETLSIDWERERPRVIWDEGVPINESSCVSCGQCVTVCPCNALMEKSMLG QAGFMTGIKEDVMEPMIDLVKNVEPGYGSIFAISEVEAAMRETRTKKTKTVCTFCGVG CSFEVWTKGRDILKIQPVSDAPVNAISTCVKGKFGWDFVNSKERITKPLIRKNGAFVE SSWEEALDLVASRLGSIKEQYGKGSVGFISSSKITNEENYVIQKLARQVFETNNVDNC SRYCQSPATDGLFRTVGMGGDAGTIKDIAKAGLVIIVGANPAEGHPVLATRVKRAHKL HGQKLIVADLRKNEMAERSDLFISPKQGTDQVWLMAVTKYMIDQGWHDQAFIDENVNY FEDYKETLKTYTLDYAERITGLSKENIIQIAEMIRDADGTCVLWGMGVTQNTGGSDTS AAISNLLLATGNYRRPGAGAYPLRGHNNVQGACDMGTLPGWLPGYQHITDDKARAKFE EAYGVEIDGKPGLDNIQMLHAIEEGKMKAMYLVGEDMALVDSNANHVHDILSSLDFFV VQDIFLSRTAQYADVVLPATPSLEKDGTFTNTERRVQRLYQALPTLGDAKPDWWIIQE VANRLGANWNYSHPSDIFSEMASLSPLFAKASYEVLEGWNSFLWGSFTGESTPLLYED GFNFPDKKARFALSDWTEPAAFPEEYDLHINNGRMLEHFHEGNMTNKSKGIQAKVPNV FVEISPELAQERGVCDGSLVRLVSPFGAVKLNALITDRVRKNELYLPMNSTDKESAIN FLTGPAADKRTNTPAYKQTKVRMEVLGGCETAPLPKTNPRNKKRHPQNGVEAERKWNR PGYVHLTD*" gene 2646807..2649749 /gene="yrhE" /locus_tag="BSU_27220" /old_locus_tag="BSU27220" CDS 2649768..2650250 /gene="yrhD" /locus_tag="BSU_27230" /old_locus_tag="BSU27230" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 10913079" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_390601.1" /db_xref="EnsemblGenomes-Gn:BSU27230" /db_xref="EnsemblGenomes-Tr:CAB14665" /db_xref="InterPro:IPR012440" /db_xref="SubtiList:BG12293" /db_xref="UniProtKB/Swiss-Prot:O05396" /translation="MATPITTIKKETKTAEQIKLEKIEELKELLAENEDAVSKTMTLM NELNDLGIFDAATSMLRAKEDIAKIALGQVSREPVTNLINTMMAAGGALTKADPEFTA KLLESVMAGTEQAQSFLKEDKKVGILDLLKAMNDPDINRAVGFGLQFLKGMGKELREQ *" gene 2649768..2650250 /gene="yrhD" /locus_tag="BSU_27230" /old_locus_tag="BSU27230" downshifts 2650230 /Source="Nicolas_upshifts" /id="D1393" /incds=0 /nref=65 /ntot=196 /MaxReadThrough="1.1227" /MaxDrop="6.19465" /score="27.8496451" /energy="-11.2" /TU="NA" /idTUdmin="U2096" /TUdmin=0 /isTUend="TRUE" CDS complement(2650286..2650516) /gene="yrhC" /locus_tag="BSU_27240" /old_locus_tag="BSU27240" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 17056751" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_390602.1" /db_xref="EnsemblGenomes-Gn:BSU27240" /db_xref="EnsemblGenomes-Tr:CAB14666" /db_xref="GOA:O05395" /db_xref="InterPro:IPR025418" /db_xref="SubtiList:BG12292" /db_xref="UniProtKB/Swiss-Prot:O05395" /translation="MNKNRMKSLKEDYKHFAFTLLAVSTFLYIGAVLPDQGLTLGQKS TMFLADCVFLAGAFFCADRSLIYKKRLEEADE*" gene complement(2650286..2650516) /gene="yrhC" /locus_tag="BSU_27240" /old_locus_tag="BSU27240" downshifts complement(2650306) /Source="Nicolas_upshifts" /id="D1394" /incds=0 /nref=60 /ntot=210 /MaxReadThrough="0.98344" /MaxDrop="5.84379" /score="15.2557797" /energy="-11.2" /TU="NA" /idTUdmin="U2097" /TUdmin=0 /isTUend="TRUE" S_feature complement(2650517..2650598) /Source="Nicolas_S_feature" /locus_tag="new_2784919_2785000_c" /HighExp="dia5, dia15, BT, Diami, B36, B60, nit, dia0, MG 10, S1" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigK, SigA, SigA" /TUshortPSig="1, 0.999, 0.998" /TUlongSig="NA" /TUlongPSig="NA" /label="S1032" CDS complement(2650599..2651738) /gene="mccB" /locus_tag="BSU_27250" /old_locus_tag="BSU27250" /EC_number="4.4.1.2" /EC_number="4.4.1.1" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:10939241, 15760717, 17056751, 18812398" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10939241, 15760717, 17056751, 18812398; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="cystathionine gamma-lyase and homocysteine gamma-lyase for reverse transsulfuration pathway" /protein_id="NP_390603.1" /db_xref="EnsemblGenomes-Gn:BSU27250" /db_xref="EnsemblGenomes-Tr:CAB14667" /db_xref="GOA:O05394" /db_xref="InterPro:IPR000277" /db_xref="InterPro:IPR015421" /db_xref="InterPro:IPR015422" /db_xref="InterPro:IPR015424" /db_xref="SubtiList:BG12291" /db_xref="UniProtKB/Swiss-Prot:O05394" /translation="MKKKTLMIHGGITGDEKTGAVSVPIYQVSTYKQPKAGQHTGYEY SRTANPTRTALEALVTELESGEAGYAFSSGMAAITAVMMLFNSGDHVVLTDDVYGGTY RVMTKVLNRLGIESTFVDTSSREEVEKAIRPNTKAIYIETPTNPLLKITDLTLMADIA KKAGVLLIVDNTFNTPYFQQPLTLGADIVLHSATKYLGGHSDVVGGLVVTASKELGEE LHFVQNSTGGVLGPQDSWLLMRGIKTLGLRMEAIDQNARKIASFLENHPAVQTLYYPG SSNHPGHELAKTQGAGFGGMISFDIGSEERVDAFLGNLKLFTIAESLGAVESLISVPA RMTHASIPRERRLELGITDGLIRISVGIEDAEDLLEDIGQALENI*" gene complement(2650599..2651738) /gene="mccB" /locus_tag="BSU_27250" /old_locus_tag="BSU27250" CDS complement(2651740..2652663) /gene="mccA" /locus_tag="BSU_27260" /old_locus_tag="BSU27260" /EC_number="2.5.1.47" /EC_number="4.2.1.-" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:10939241, 15760717, 17056751, 18812398" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10939241, 15760717, 17056751, 18812398; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="cystathionine beta-synthase for the reverse transsulfuration pathway" /protein_id="NP_390604.1" /db_xref="EnsemblGenomes-Gn:BSU27260" /db_xref="EnsemblGenomes-Tr:CAB14668" /db_xref="GOA:O05393" /db_xref="InterPro:IPR001216" /db_xref="InterPro:IPR001926" /db_xref="InterPro:IPR036052" /db_xref="SubtiList:BG12290" /db_xref="UniProtKB/Swiss-Prot:O05393" /translation="MTVITDITELIGNTPLLRLKNFDVPEGVAVYAKLEMMNPGGSIK DRLGDMLIRDALDSGKVKPGGVIIEATAGNTGIGLALSARKYGLKAIFCVPEHFSREK QQIMQALGASIIHTPRQDGMQGAIQKAIQLETEIENSYCVLQFKNRVNPSTYYKTLGP EMWEALDGNIHTFVAGAGSGGTFAGTASFLKEKNPAVKTVIVEPVGSILNGGEPHAHK TEGIGMEFIPDYMDKSHFDEIYTVTDENAFRLVKEAAEKEGLLIGSSSGAALYAALEE AKKASAGTNIVTVFPDSSDRYISKQIYEGGI*" gene complement(2651740..2652663) /gene="mccA" /locus_tag="BSU_27260" /old_locus_tag="BSU27260" downshifts complement(2652656) /Source="Nicolas_upshifts" /id="D1395" /incds=0 /nref=16 /ntot=178 /MaxReadThrough="7.13056" /MaxDrop="3.40819" /score="0.994445584" /energy="-8.7" /TU="U2097,U2098,U2099" /idTUdmin="U2102" /TUdmin=1874 /isTUend="FALSE" S_feature complement(2652664..2652727) /Source="Nicolas_S_feature" /locus_tag="new_2787066_2787129_c" /HighExp="dia5, Diami, dia15, BT, B36, S6, LBGstat, S8, dia0, B60" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigK, SigA, SigA" /TUshortPSig="1, 0.999, 0.998" /TUlongSig="NA" /TUlongPSig="NA" /label="S1033" CDS complement(2652728..2653423) /gene="mtnN" /locus_tag="BSU_27270" /old_locus_tag="BSU27270" /EC_number="3.2.2.9" /EC_number="3.2.2.16" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:10574451, 10939241, 15102328, 17056751, 24509311, 25849497, 25849889" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10574451, 10939241, 15102328, 17056751, 24509311, 25849497, 25849889; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="methylthioadenosine / S-adenosylhomocysteine nucleosidase" /protein_id="NP_390605.1" /db_xref="EnsemblGenomes-Gn:BSU27270" /db_xref="EnsemblGenomes-Tr:CAB14669" /db_xref="GOA:O32028" /db_xref="InterPro:IPR000845" /db_xref="InterPro:IPR010049" /db_xref="InterPro:IPR035994" /db_xref="SubtiList:BG13800" /db_xref="UniProtKB/Swiss-Prot:O32028" /translation="MRLAVIGAMEEEVTILRNKLENAKTETIAHCEFTTGEYEGTEVI LLKSGIGKVNAAISTTLLLDRYKPDYVINTGSAGGFHHTLNVGDVVISTDVRHHDVDV TAFDYEYGQVPGLPAAYAADEKLISITEEAVSELDGIQVAKGTIATGDSFMNDPKRVE EVRARFSDLYAVEMEAAAVAQVCHQFKTPFVVIRALSDIAGKESHVSFDQFLEQAAVH STELVLKVIKRIH*" gene complement(2652728..2653423) /gene="mtnN" /locus_tag="BSU_27270" /old_locus_tag="BSU27270" promotor_-10 complement(2653163..2653182) /Source="Nicolas_upshift_promotors" /id="U2097" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1315 /SigmaFactorBS="tctgcttgaccgttacaagcctgattatgtcattaacACAGG CTCAGccggcggatttcATCATACATTGAATGTAGGGgatgtcgtcatttccactgac g" /listShort="S1033, mccA, mccB, S1032, yrhC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2653181) /Source="Nicolas_upshifts" /id="U2097" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1315 /SigmaFactorBS="tctgcttgaccgttacaagcctgattatgtcattaacACAGG CTCAGccggcggatttcATCATACATTGAATGTAGGGgatgtcgtcatttccactgac g" /listShort="S1033, mccA, mccB, S1032, yrhC" /GFF_Attribute="listLong" promotor_-35 complement(2653195..2653204) /Source="Nicolas_upshift_promotors" /id="U2097" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1315 /SigmaFactorBS="tctgcttgaccgttacaagcctgattatgtcattaacACAGG CTCAGccggcggatttcATCATACATTGAATGTAGGGgatgtcgtcatttccactgac g" /listShort="S1033, mccA, mccB, S1032, yrhC" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2653444..2654085) /gene="yrrT" /locus_tag="BSU_27280" /old_locus_tag="BSU27280" /EC_number="2.1.1.-" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 10939241, 17056751; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative AdoMet-dependent methyltransferase" /protein_id="NP_390606.1" /db_xref="EnsemblGenomes-Gn:BSU27280" /db_xref="EnsemblGenomes-Tr:CAB14670" /db_xref="GOA:O32029" /db_xref="InterPro:IPR001737" /db_xref="InterPro:IPR020598" /db_xref="InterPro:IPR023553" /db_xref="InterPro:IPR029063" /db_xref="SubtiList:BG13799" /db_xref="UniProtKB/Swiss-Prot:O32029" /translation="MGREFIPLFEDWAATYDQTVQGLDIQYKEAFRGYDHILDAIVRK SGTHVLEFGPGTGNLTAKLLDAGKTVFGIEPSPAMRKLASDKLSGRTEIVDGDFLTFP EPPFQADTIVSSYAFHHLTDEEKRAAIKQYGKYLHLHDKIVFADTVFENAQAYQQAID KARSQGFYQLANDLETEHYPTLDALKEMFTAEGFAVRFTQQNDFVWIMEAIKR*" gene complement(2653444..2654085) /gene="yrrT" /locus_tag="BSU_27280" /old_locus_tag="BSU27280" promotor_-10 complement(2653652..2653671) /Source="Nicolas_upshift_promotors" /id="U2098" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.498501498501498" /psig="0.999000999001" /xcortree=2663 /SigmaFactorBS="catttgactgacgaagaaaagcgggctgccataaagcaatAT GGcaaataccttcacttgCATGATAAAATAGTGTTTGCcgataccgtctttgaaaatg c" /listShort="mtnN, S1033, mccA, mccB, S1032, yrhC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2653671) /Source="Nicolas_upshifts" /id="U2098" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.498501498501498" /psig="0.999000999001" /xcortree=2663 /SigmaFactorBS="catttgactgacgaagaaaagcgggctgccataaagcaatAT GGcaaataccttcacttgCATGATAAAATAGTGTTTGCcgataccgtctttgaaaatg c" /listShort="mtnN, S1033, mccA, mccB, S1032, yrhC" /GFF_Attribute="listLong" promotor_-35 complement(2653688..2653691) /Source="Nicolas_upshift_promotors" /id="U2098" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.498501498501498" /psig="0.999000999001" /xcortree=2663 /SigmaFactorBS="catttgactgacgaagaaaagcgggctgccataaagcaatAT GGcaaataccttcacttgCATGATAAAATAGTGTTTGCcgataccgtctttgaaaatg c" /listShort="mtnN, S1033, mccA, mccB, S1032, yrhC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 2654137..2654146 /Source="Nicolas_upshift_promotors" /id="U2100" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.975024975024975" /psig="0.975024975024975" /xcortree=1274 /SigmaFactorBS="taattcctataagtatactatggattaatGATGGAACAGttc ctataatacCACATATTCTGAAAAGCAGGtactaaaacactttgtgtattttatgcca t" /listShort="S1034, yrzA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(2654143..2654162) /Source="Nicolas_upshift_promotors" /id="U2099" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.436563436563437" /psig="0.998001998001998" /xcortree=1746 /SigmaFactorBS="gatggcataaaatacacaaagtgttttaGTACctgcttttca gaataTGTGGTATTATAGGAACTGTtccatcattaatccatagtatacttataggaat t" /listShort="yrrT, mtnN, S1033, mccA, mccB, S1032, yrhC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2654149) /Source="Nicolas_upshifts" /id="U2099" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.436563436563437" /psig="0.998001998001998" /xcortree=1746 /SigmaFactorBS="gatggcataaaatacacaaagtgttttaGTACctgcttttca gaataTGTGGTATTATAGGAACTGTtccatcattaatccatagtatacttataggaat t" /listShort="yrrT, mtnN, S1033, mccA, mccB, S1032, yrhC" /GFF_Attribute="listLong" promotor_-10 2654159..2654178 /Source="Nicolas_upshift_promotors" /id="U2100" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.975024975024975" /psig="0.975024975024975" /xcortree=1274 /SigmaFactorBS="taattcctataagtatactatggattaatGATGGAACAGttc ctataatacCACATATTCTGAAAAGCAGGtactaaaacactttgtgtattttatgcca t" /listShort="S1034, yrzA" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 2654168..2654232 /Source="Nicolas_S_feature" /locus_tag="new_2788570_2788634" /HighExp="BT, S6, S7, S8, S5, B36, G/S, Pyr, C30, B60" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigK" /TUshortPSig="0.975" /TUlongSig="NA" /TUlongPSig="NA" /label="S1034" upshifts 2654168 /Source="Nicolas_upshifts" /id="U2100" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.975024975024975" /psig="0.975024975024975" /xcortree=1274 /SigmaFactorBS="taattcctataagtatactatggattaatGATGGAACAGttc ctataatacCACATATTCTGAAAAGCAGGtactaaaacactttgtgtattttatgcca t" /listShort="S1034, yrzA" /GFF_Attribute="listLong" promotor_-35 complement(2654178..2654181) /Source="Nicolas_upshift_promotors" /id="U2099" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.436563436563437" /psig="0.998001998001998" /xcortree=1746 /SigmaFactorBS="gatggcataaaatacacaaagtgttttaGTACctgcttttca gaataTGTGGTATTATAGGAACTGTtccatcattaatccatagtatacttataggaat t" /listShort="yrrT, mtnN, S1033, mccA, mccB, S1032, yrhC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 2654213..2654220 /Source="Nicolas_upshift_promotors" /id="U2101" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.471528471528472" /psig="0.837162837162837" /xcortree=2723 /SigmaFactorBS="gcaggtactaaaacactttgtgtattttatgccatctcaTAT TGCGCattgaccgcaaaaaaGCTTATACTTCATATGACttgtgaaagctggagggtca a" /listShort="yrzA" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 2654234 /Source="Nicolas_upshifts" /id="U2101" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.471528471528472" /psig="0.837162837162837" /xcortree=2723 /SigmaFactorBS="gcaggtactaaaacactttgtgtattttatgccatctcaTAT TGCGCattgaccgcaaaaaaGCTTATACTTCATATGACttgtgaaagctggagggtca a" /listShort="yrzA" /GFF_Attribute="listLong" promotor_-10 2654236..2654253 /Source="Nicolas_upshift_promotors" /id="U2101" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.471528471528472" /psig="0.837162837162837" /xcortree=2723 /SigmaFactorBS="gcaggtactaaaacactttgtgtattttatgccatctcaTAT TGCGCattgaccgcaaaaaaGCTTATACTTCATATGACttgtgaaagctggagggtca a" /listShort="yrzA" /GFF_Attribute="listLong" /label="promotor_-10" CDS 2654278..2654481 /gene="yrzA" /locus_tag="BSU_27290" /old_locus_tag="BSU27290" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_390607.1" /db_xref="EnsemblGenomes-Gn:BSU27290" /db_xref="EnsemblGenomes-Tr:CAB14671" /db_xref="InterPro:IPR019686" /db_xref="SubtiList:BG13811" /db_xref="UniProtKB/Swiss-Prot:O32030" /translation="MNFQLDLIKDKVEFFEAASLQELEKKINTQIENNKAIMLRVKSV SHQTLVAEGRILYSAVVHFSAEA*" gene 2654278..2654481 /gene="yrzA" /locus_tag="BSU_27290" /old_locus_tag="BSU27290" downshifts 2654488 /Source="Nicolas_upshifts" /id="D1396" /incds=0 /nref=205 /ntot=257 /MaxReadThrough="1.11529" /MaxDrop="5.39095" /score="26.0850303" /energy="-14.2" /TU="NA" /idTUdmin="U2101" /TUdmin="-10" /isTUend="TRUE" CDS complement(2654518..2655219) /gene="yrrS" /locus_tag="BSU_27300" /old_locus_tag="BSU27300" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 14679248" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_390608.1" /db_xref="EnsemblGenomes-Gn:BSU27300" /db_xref="EnsemblGenomes-Tr:CAB14672" /db_xref="GOA:O32031" /db_xref="InterPro:IPR009988" /db_xref="SubtiList:BG13798" /db_xref="UniProtKB/Swiss-Prot:O32031" /translation="MSNNQSRYENRDKRRKANLVLNILIAIVSILIVVVAANLFINSP SSKDVSKDSETAQKQESPASGKTEKKSDEDIKDSKKDTSDSEKDSEKSSDSDSKKDDS SSKKDDSDSDSSSDSAGDGLKDAKVTEGGSSSDVEKTYENPDWKAVGTEQTGEHAATY DSSSQDWAEMLKAISYATGVSTDNMTVLWLGNNGSPQDAKGKILDKATGNKYQVTITW VDEKGWKPTKVEKLK*" gene complement(2654518..2655219) /gene="yrrS" /locus_tag="BSU_27300" /old_locus_tag="BSU27300" downshifts complement(2654530) /Source="Nicolas_upshifts" /id="D1397" /incds=0 /nref=237 /ntot=265 /MaxReadThrough="1.64695" /MaxDrop="6.48551" /score="22.1367505" /energy="-14.2" /TU="NA" /idTUdmin="U2102" /TUdmin=0 /isTUend="TRUE" CDS complement(2655284..2657038) /gene="pbpI" /locus_tag="BSU_27310" /old_locus_tag="BSU27310" /function="16.8: Protect" /function="16.2: Construct biomass (Anabolism)" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:14679248" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 14679248; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="penicillin-binding protein PBP4B" /protein_id="NP_390609.1" /db_xref="EnsemblGenomes-Gn:BSU27310" /db_xref="EnsemblGenomes-Tr:CAB14673" /db_xref="GOA:O32032" /db_xref="InterPro:IPR001460" /db_xref="InterPro:IPR005311" /db_xref="InterPro:IPR012338" /db_xref="InterPro:IPR036138" /db_xref="SubtiList:BG13797" /db_xref="UniProtKB/Swiss-Prot:O32032" /translation="MKISKRMKLAVIAFLIVFFLLLLRLAEIQLFFTESFSKKKINLI QESVKQRTEEVLISDGRGSFLDRNGRALTGQSEPAVVLFPFLLTQDWPIKKVADILGM SEDDLRQTLGQAKKPVILQQKKIKTLSKQSITKINSLKYPGIYGVYMENEDKPSLASH TIGSTNQDPALLRKKYPDKESLPITTEIGTTGLERTFDEFLLPEQDTKLLYHVDGKGN PLFGMDVKYTAEANTFYPLQIKTTIDQSIQKAMEEVLDEQGLKKGGAVLLDIENSSVL GIVSKPDADVSRQNTLQNYMLTPIYPGSVFKTVIAAAAIENNMVKPSQTFNCNLNLYG EPGDDKGTLSFDESFAQSCNYTFTSLAEQLMKKDSSVIEDMSEKLALTDRAGWEGKLY HETDFRQLYNEKSGVIWGDEKDKSVKKAIAQTAIGQKNVKVTPLEVANMMATIARGGE KRQVKIAEQIEYKNGTTLVTFKDQKLKGETIDKYTSQQLQKILRRVVESPSGTGRRFQ DLPYTVAGKSGTAQTGKLSKEKETLYEKWFAGYFPADKPKYALVVLHMDTPGDKALTN SVFYDIVKKVHEIEINQK*" gene complement(2655284..2657038) /gene="pbpI" /locus_tag="BSU_27310" /old_locus_tag="BSU27310" misc_feature complement(2655312..2655331) /Source="Nicolas_upshift_promotors" /id="U2102" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.938061938061938" /psig="0.998001998001998" /xcortree=2157 /SigmaFactorBS="gttttacacatggatacaccgggagataaggctctgacaaat tcggtgtttTATGATATTGTTAAAAAAGTacacgaaattgaaatcaatcagaaataga a" /listShort="yrrS" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(2655322) /Source="Nicolas_upshifts" /id="U2102" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.938061938061938" /psig="0.998001998001998" /xcortree=2157 /SigmaFactorBS="gttttacacatggatacaccgggagataaggctctgacaaat tcggtgtttTATGATATTGTTAAAAAAGTacacgaaattgaaatcaatcagaaataga a" /listShort="yrrS" /GFF_Attribute="listLong" promotor_-10 complement(2656353..2656368) /Source="Nicolas_upshift_promotors" /id="U2103" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1643 /SigmaFactorBS="agcttttatatcatgtggacggaaaaGGAAACCCTTtgtttg gcatggACGTCAAATATACAGCtgaagccaatacattttatccgctccagatcaaaac a" /listShort="yrrS" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2656356) /Source="Nicolas_upshifts" /id="U2103" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1643 /SigmaFactorBS="agcttttatatcatgtggacggaaaaGGAAACCCTTtgtttg gcatggACGTCAAATATACAGCtgaagccaatacattttatccgctccagatcaaaac a" /listShort="yrrS" /GFF_Attribute="listLong" promotor_-35 complement(2656381..2656390) /Source="Nicolas_upshift_promotors" /id="U2103" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1643 /SigmaFactorBS="agcttttatatcatgtggacggaaaaGGAAACCCTTtgtttg gcatggACGTCAAATATACAGCtgaagccaatacattttatccgctccagatcaaaac a" /listShort="yrrS" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(2656584..2656602) /Source="Nicolas_upshift_promotors" /id="U2104" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.96103896103896" /psig="0.96103896103896" /xcortree=975 /SigmaFactorBS="actttcaaaacaatctatcacaaaaatcaattctttGAAATA tcccggcatttacgGCGTATATATGGAGAATGAagacaagcccagccttgcttcacat a" /listShort="yrrS" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2656598) /Source="Nicolas_upshifts" /id="U2104" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.96103896103896" /psig="0.96103896103896" /xcortree=975 /SigmaFactorBS="actttcaaaacaatctatcacaaaaatcaattctttGAAATA tcccggcatttacgGCGTATATATGGAGAATGAagacaagcccagccttgcttcacat a" /listShort="yrrS" /GFF_Attribute="listLong" promotor_-35 2656617..2656624 /Source="Nicolas_upshift_promotors" /id="U2105" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.805194805194805" /psig=1 /xcortree=3003 /SigmaFactorBS="tcattctccatatatacgccgtaaatgccgggaTATTTCAAa gaattgatttttgTGATAGATTGTTTTGAAAGTgttttgattttcttttgctgcaaaa t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 complement(2656617..2656622) /Source="Nicolas_upshift_promotors" /id="U2104" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.96103896103896" /psig="0.96103896103896" /xcortree=975 /SigmaFactorBS="actttcaaaacaatctatcacaaaaatcaattctttGAAATA tcccggcatttacgGCGTATATATGGAGAATGAagacaagcccagccttgcttcacat a" /listShort="yrrS" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2656639..2656658 /Source="Nicolas_upshift_promotors" /id="U2105" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.805194805194805" /psig=1 /xcortree=3003 /SigmaFactorBS="tcattctccatatatacgccgtaaatgccgggaTATTTCAAa gaattgatttttgTGATAGATTGTTTTGAAAGTgttttgattttcttttgctgcaaaa t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2656644 /Source="Nicolas_upshifts" /id="U2105" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.805194805194805" /psig=1 /xcortree=3003 /SigmaFactorBS="tcattctccatatatacgccgtaaatgccgggaTATTTCAAa gaattgatttttgTGATAGATTGTTTTGAAAGTgttttgattttcttttgctgcaaaa t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" CDS complement(2657092..2657565) /gene="greA" /locus_tag="BSU_27320" /old_locus_tag="BSU27320" /function="16.2: Construct biomass (Anabolism)" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:10910724, 16014871, 16707701, 21515770, 28976965" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10910724, 16014871, 16707701, 21515770, 28976965; Product type f: factor" /codon_start=1 /transl_table=11 /product="transcription elongation factor resolving backtracking / stalling" /protein_id="NP_390610.1" /db_xref="EnsemblGenomes-Gn:BSU27320" /db_xref="EnsemblGenomes-Tr:CAB14674" /db_xref="GOA:P80240" /db_xref="InterPro:IPR001437" /db_xref="InterPro:IPR006359" /db_xref="InterPro:IPR018151" /db_xref="InterPro:IPR022691" /db_xref="InterPro:IPR023459" /db_xref="InterPro:IPR028624" /db_xref="InterPro:IPR036805" /db_xref="InterPro:IPR036953" /db_xref="SubtiList:BG19019" /db_xref="UniProtKB/Swiss-Prot:P80240" /translation="MAQEKVFPMTAEGKQKLEQELEYLKTVKRKEVVERIKIARSFGD LSENSEYDSAKEEQAFVEGRVTTLENMIRNAKIIEDDGGSNVVGLGKTVTFVELPDGD EESYTIVGSAEADPFEGKISNDSPIAKSLLGKKVDEEVTVQTPGGEMLVKIVKIS*" gene complement(2657092..2657565) /gene="greA" /locus_tag="BSU_27320" /old_locus_tag="BSU27320" downshifts complement(2657099) /Source="Nicolas_upshifts" /id="D1398" /incds=0 /nref=130 /ntot=229 /MaxReadThrough="5.30316" /MaxDrop="4.90519" /score="34.2316821" /energy="-17" /TU="U2107" /idTUdmin="U2106" /TUdmin="-17" /isTUend="TRUE" S_feature complement(2657566..2657698) /Source="Nicolas_S_feature" /locus_tag="new_2791968_2792100_c" /HighExp="HPh, C90, dia5, dia15, Diami, H2O2, dia0, Etha, G180, Oxctl" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA, SigA, SigA" /TUshortPSig="0.998, 1, 1, 0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S1035" promotor_-10 complement(2657680..2657699) /Source="Nicolas_upshift_promotors" /id="U2106" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.839160839160839" /psig="0.998001998001998" /xcortree=1924 /SigmaFactorBS="gtgcgaattcccttctttccctgtttataaacgcgaaaTATT TGCAgaacgacacgattCAGTTTAAGATAAACAGTACctatatgggagagaagaacga g" /listShort="S1035, greA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2657698) /Source="Nicolas_upshifts" /id="U2106" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.839160839160839" /psig="0.998001998001998" /xcortree=1924 /SigmaFactorBS="gtgcgaattcccttctttccctgtttataaacgcgaaaTATT TGCAgaacgacacgattCAGTTTAAGATAAACAGTACctatatgggagagaagaacga g" /listShort="S1035, greA" /GFF_Attribute="listLong" S_feature complement(2657700..2657808) /Source="Nicolas_S_feature" /locus_tag="new_2792102_2792210_c" /HighExp="HPh, G180, G135, LBGexp, dia0, Paraq, Oxctl, G150, LPh, H2O2" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA, SigA" /TUshortPSig="1, 1, 0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S1036" promotor_-35 complement(2657713..2657720) /Source="Nicolas_upshift_promotors" /id="U2106" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.839160839160839" /psig="0.998001998001998" /xcortree=1924 /SigmaFactorBS="gtgcgaattcccttctttccctgtttataaacgcgaaaTATT TGCAgaacgacacgattCAGTTTAAGATAAACAGTACctatatgggagagaagaacga g" /listShort="S1035, greA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(2657801..2657820) /Source="Nicolas_upshift_promotors" /id="U2107" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.656343656343656" /psig=1 /xcortree=2659 /SigmaFactorBS="atctgatggtcacaaaaattcaaaccatTCTTGaacaaaacg cgatttTGTAATACCATAGCATAGACataaataactctgaccatattatgtataggca g" /listShort="S1036, S1035, greA, pbpI" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2657808) /Source="Nicolas_upshifts" /id="U2107" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.656343656343656" /psig=1 /xcortree=2659 /SigmaFactorBS="atctgatggtcacaaaaattcaaaccatTCTTGaacaaaacg cgatttTGTAATACCATAGCATAGACataaataactctgaccatattatgtataggca g" /listShort="S1036, S1035, greA, pbpI" /GFF_Attribute="listLong" CDS complement(2657816..2658451) /gene="udk" /locus_tag="BSU_27330" /old_locus_tag="BSU27330" /EC_number="2.7.1.48" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2b: Function from indirect experimental evidences (e.g. phenotypes); PubMedId: 6208029; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="uridine kinase" /protein_id="NP_390611.1" /db_xref="EnsemblGenomes-Gn:BSU27330" /db_xref="EnsemblGenomes-Tr:CAB14675" /db_xref="GOA:O32033" /db_xref="InterPro:IPR000764" /db_xref="InterPro:IPR006083" /db_xref="InterPro:IPR026008" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG12696" /db_xref="UniProtKB/Swiss-Prot:O32033" /translation="MGKNPVVIGIAGGSGSGKTSVTRSIYEQFKGHSILMIQQDLYYK DQSHLPFEERLNTNYDHPLAFDNDYLIEHIQDLLNYRPIEKPIYDYKLHTRSEETVHV EPKDVIILEGILVLEDKRLRDLMDIKLYVDTDADLRIIRRIMRDINERGRSIDSVIEQ YVSVVRPMHNQFVEPTKRYADIIIPEGGQNHVAIDLMVTKIQTILEQNAIL*" gene complement(2657816..2658451) /gene="udk" /locus_tag="BSU_27330" /old_locus_tag="BSU27330" promotor_-35 complement(2657836..2657840) /Source="Nicolas_upshift_promotors" /id="U2107" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.656343656343656" /psig=1 /xcortree=2659 /SigmaFactorBS="atctgatggtcacaaaaattcaaaccatTCTTGaacaaaacg cgatttTGTAATACCATAGCATAGACataaataactctgaccatattatgtataggca g" /listShort="S1036, S1035, greA, pbpI" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 2657946..2657951 /Source="Nicolas_upshift_promotors" /id="U2108" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.865134865134865" /psig="0.865134865134865" /xcortree=1199 /SigmaFactorBS="cgtatcgtttcgtcggctcgacgaattggttaTGCATCggac ggaccactgacACATATTGTTCAATGACAGaatcaatagagcgtccgcgctcattaat a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2657967..2657985 /Source="Nicolas_upshift_promotors" /id="U2108" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.865134865134865" /psig="0.865134865134865" /xcortree=1199 /SigmaFactorBS="cgtatcgtttcgtcggctcgacgaattggttaTGCATCggac ggaccactgacACATATTGTTCAATGACAGaatcaatagagcgtccgcgctcattaat a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2657974 /Source="Nicolas_upshifts" /id="U2108" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.865134865134865" /psig="0.865134865134865" /xcortree=1199 /SigmaFactorBS="cgtatcgtttcgtcggctcgacgaattggttaTGCATCggac ggaccactgacACATATTGTTCAATGACAGaatcaatagagcgtccgcgctcattaat a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" CDS complement(2658458..2659726) /gene="yrrO" /locus_tag="BSU_27340" /old_locus_tag="BSU27340" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative hydrolase large subunit" /protein_id="NP_390612.1" /db_xref="EnsemblGenomes-Gn:BSU27340" /db_xref="EnsemblGenomes-Tr:CAB14676" /db_xref="GOA:O32034" /db_xref="InterPro:IPR001539" /db_xref="InterPro:IPR013785" /db_xref="InterPro:IPR032525" /db_xref="SubtiList:BG13796" /db_xref="UniProtKB/Swiss-Prot:O32034" /translation="MTAVNDKISTIVNGKRVITKKPELLAPAGNLEKLKIAVHYGADA VFIGGQEYGLRSNADNFTIEEIAEGVEFAKKYGAKIYVTTNIFAHNENMDGLEDYLKA LGDANVAGIIVADPLIIETCRRVAPNVEVHLSTQQSLSNWKAVQFWKEEGLDRVVLAR ETSALEIREMKEKVDIEIESFIHGAMCIAYSGRCVLSNHMTARDSNRGGCCQSCRWDY DLYQTDGANAVALYGEEDAPFAMSPKDLKLIESIPKMIEMGIDSLKIEGRMKSIHYVA TVVSVYRKVIDAYCADPENFVIQKEWLEELDKCANRDTATAFFEGTPGYEEQMFGEHA KKTTYDFVGLVLNYDEDTQMVTLQQRNFFKKGDEVEFFGPEIENFTHTIETIWDEDGN ELDAARHPLQIVKFKLDKKIYPSNMMRKGK*" gene complement(2658458..2659726) /gene="yrrO" /locus_tag="BSU_27340" /old_locus_tag="BSU27340" CDS complement(2659745..2660674) /gene="yrrN" /locus_tag="BSU_27350" /old_locus_tag="BSU27350" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative hydrolase small subunit" /protein_id="NP_390613.1" /db_xref="EnsemblGenomes-Gn:BSU27350" /db_xref="EnsemblGenomes-Tr:CAB14677" /db_xref="GOA:O32035" /db_xref="InterPro:IPR001539" /db_xref="InterPro:IPR013785" /db_xref="SubtiList:BG13795" /db_xref="UniProtKB/Swiss-Prot:O32035" /translation="MKKPELLVTPTSTADILPLIQAGATAFLVGEQRYGLRLAGEFSR EDVTKAVEIAHKEGAKVYVAVNAIFHNDKVGELGEYLAFLAEAGVDAAVFGDPAVLMA ARESAPDLKLHWSTETTGTNYYTCNYWGRKGAARSVLARELNMDSIVEIKENAEVEIE IQVHGMTCMFQSKRSLIGNYFEYQGKVMDIERKKKESGMFLHDKERDNKYPIFEDENG THIMSPNDVCIIDELEELIDAGIDSFKIDGVLKMPEYLIEVTKMYREAIDLCVENRDE YEAKKEDWIERIESIQPVNRKIDTGFFFKETVY*" gene complement(2659745..2660674) /gene="yrrN" /locus_tag="BSU_27350" /old_locus_tag="BSU27350" CDS complement(2660680..2661333) /gene="yrrM" /locus_tag="BSU_27360" /old_locus_tag="BSU27360" /EC_number="2.1.1.-" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative acyl-CoA O-methyltransferase" /protein_id="NP_390614.1" /db_xref="EnsemblGenomes-Gn:BSU27360" /db_xref="EnsemblGenomes-Tr:CAB14678" /db_xref="GOA:O32036" /db_xref="InterPro:IPR002935" /db_xref="InterPro:IPR029063" /db_xref="SubtiList:BG13794" /db_xref="UniProtKB/Swiss-Prot:O32036" /translation="MTDRYEQINDYIEALLKPRPDNVKRLEAYAEEHHVPIMEKAGME VLLQILSVKQPKKILEIGTAIGYSAIRMALELPSAEIYTIERNEKRHEEAVNNIKEFQ LDDRIHVFYGDALELADAVHVTAPYDVIFIDAAKGQYQNFFHLYEPMLSPDGVIITDN VLFKGLVAEDYSKIEPKRRRRLVAKIDEYNHWLMNHPDYQTAIIPVGDGLAISKKKR* " gene complement(2660680..2661333) /gene="yrrM" /locus_tag="BSU_27360" /old_locus_tag="BSU27360" S_feature complement(2661334..2661438) /Source="Nicolas_S_feature" /locus_tag="new_2795736_2795840_c" /HighExp="LBGexp, G180, H2O2, G150, Paraq, Oxctl, G135, dia15, C30, LBGstat" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="1, 0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S1037" promotor_-10 complement(2661420..2661439) /Source="Nicolas_upshift_promotors" /id="U2109" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.586413586413586" /psig=1 /xcortree=2599 /SigmaFactorBS="aaaatgagaaataaaaggagagcaaaaagctctccttttGTT CGctttccgcaaggtttTATGATAAAATATATCGGGTtgtttaccgatgtatcatgat g" /listShort="S1037, yrrM, yrrN, yrrO, udk, S1036, S1035, greA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2661438) /Source="Nicolas_upshifts" /id="U2109" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.586413586413586" /psig=1 /xcortree=2599 /SigmaFactorBS="aaaatgagaaataaaaggagagcaaaaagctctccttttGTT CGctttccgcaaggtttTATGATAAAATATATCGGGTtgtttaccgatgtatcatgat g" /listShort="S1037, yrrM, yrrN, yrrO, udk, S1036, S1035, greA" /GFF_Attribute="listLong" promotor_-35 complement(2661455..2661459) /Source="Nicolas_upshift_promotors" /id="U2109" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.586413586413586" /psig=1 /xcortree=2599 /SigmaFactorBS="aaaatgagaaataaaaggagagcaaaaagctctccttttGTT CGctttccgcaaggtttTATGATAAAATATATCGGGTtgtttaccgatgtatcatgat g" /listShort="S1037, yrrM, yrrN, yrrO, udk, S1036, S1035, greA" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2661485..2662567) /gene="yrrL" /locus_tag="BSU_27370" /old_locus_tag="BSU27370" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 22333191" /codon_start=1 /transl_table=11 /product="conserved membrane associated protein" /protein_id="NP_390615.1" /db_xref="EnsemblGenomes-Gn:BSU27370" /db_xref="EnsemblGenomes-Tr:CAB14679" /db_xref="GOA:O34758" /db_xref="InterPro:IPR003770" /db_xref="SubtiList:BG13793" /db_xref="UniProtKB/Swiss-Prot:O34758" /translation="MYINQQKKSFFNKKRIILSSIVVLFLIIGGAFLYGKSLLEPVEK DSKTTVNINIPSGSSVSAIASILKKNDVIKSEKAFQYYVKYKGASGFQAGFYHLNKGM DLDAIIQKLTSGATGYAFQITVTEGAQLTQIAAAIADETKYSKKQVIAKLDDETFINQ LKKEFPDTVTNDVFNKNIKHPLEGYLFPATYPFNDPDTSLEDIIKAMIKQTNSYVETY KSEMKKNKVSVHKLLTMASLIEEEATEKADRHKIASVFYNRLKKKMPLQTDPTVLYAA GKHKDRVLYKDLEIDSPYNTYKNTGLTPGPIANAGMSSWEAALHPDKTDYLYFLAKSN GEVVFTKTLKEHNKAKEKYISSKNEK*" gene complement(2661485..2662567) /gene="yrrL" /locus_tag="BSU_27370" /old_locus_tag="BSU27370" downshifts complement(2661519) /Source="Nicolas_upshifts" /id="D1399" /incds=0 /nref=21 /ntot=144 /MaxReadThrough="3.5258" /MaxDrop="3.97301" /score="10.5327118" /energy="-11" /TU="U2110" /idTUdmin="U2111" /TUdmin=1173 /isTUend="FALSE" promotor_-10 complement(2662583..2662602) /Source="Nicolas_upshift_promotors" /id="U2110" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.718281718281718" /psig="0.999000999001" /xcortree=2524 /SigmaFactorBS="ctccggcttttttctgctttatgcaggcctctttttgtaata aATTGccgaaatacaatgaATCATGTAGTATAAGAGCTGatgggaggagacctaatgt a" /listShort="yrrL, S1037, yrrM, yrrN, yrrO, udk, S1036, S1035, greA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2662603) /Source="Nicolas_upshifts" /id="U2110" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.718281718281718" /psig="0.999000999001" /xcortree=2524 /SigmaFactorBS="ctccggcttttttctgctttatgcaggcctctttttgtaata aATTGccgaaatacaatgaATCATGTAGTATAAGAGCTGatgggaggagacctaatgt a" /listShort="yrrL, S1037, yrrM, yrrN, yrrO, udk, S1036, S1035, greA" /GFF_Attribute="listLong" promotor_-35 complement(2662617..2662620) /Source="Nicolas_upshift_promotors" /id="U2110" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.718281718281718" /psig="0.999000999001" /xcortree=2524 /SigmaFactorBS="ctccggcttttttctgctttatgcaggcctctttttgtaata aATTGccgaaatacaatgaATCATGTAGTATAAGAGCTGatgggaggagacctaatgt a" /listShort="yrrL, S1037, yrrM, yrrN, yrrO, udk, S1036, S1035, greA" /GFF_Attribute="listLong" /label="promotor_-35" downshifts complement(2662693) /Source="Nicolas_upshifts" /id="D1400" /incds=0 /nref=260 /ntot=268 /MaxReadThrough="2.55298" /MaxDrop="6.9121" /score="36.0941054" /energy="-15" /TU="NA" /idTUdmin="U2111" /TUdmin="-1" /isTUend="TRUE" CDS complement(2662698..2662979) /gene="yrzB" /locus_tag="BSU_27380" /old_locus_tag="BSU27380" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 22333191; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative nucleic acid binding protein" /protein_id="NP_390616.1" /db_xref="EnsemblGenomes-Gn:BSU27380" /db_xref="EnsemblGenomes-Tr:CAB14680" /db_xref="InterPro:IPR009711" /db_xref="SubtiList:BG13812" /db_xref="UniProtKB/Swiss-Prot:O34828" /translation="MEHGEKNITIVDDQGNEQLCEVLFTFENEEFGKSYVLYYPIESK DDEEVEILASSFTPNEDGENGELFPIETDEEWDMIEETLNTFLADEDEE*" gene complement(2662698..2662979) /gene="yrzB" /locus_tag="BSU_27380" /old_locus_tag="BSU27380" downshifts complement(2662758) /Source="Nicolas_upshifts" /id="D1401" /incds=1 /nref=1 /ntot=1 /MaxReadThrough="6.68915" /MaxDrop="5.19246" /score="36.0941054" /energy="-15" /TU="U2111,U2113,U2114,U2115" /idTUdmin="U2111" /TUdmin="-66" /isTUend="FALSE" CDS complement(2662997..2663413) /gene="rimF" /locus_tag="BSU_27390" /old_locus_tag="BSU27390" /function="16.6: Maintain" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 15044829, 14512736, 16021622, 22720735, 23251031, 25545592; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="pre-16S ribosomal RNA maturation enzyme" /protein_id="NP_390617.1" /db_xref="EnsemblGenomes-Gn:BSU27390" /db_xref="EnsemblGenomes-Tr:CAB14681" /db_xref="GOA:O34634" /db_xref="InterPro:IPR005227" /db_xref="InterPro:IPR006641" /db_xref="InterPro:IPR012337" /db_xref="InterPro:IPR037027" /db_xref="PDB:1VHX" /db_xref="SubtiList:BG13792" /db_xref="UniProtKB/Swiss-Prot:O34634" /translation="MRILGLDLGTKTLGVALSDEMGWTAQGIETIKINEAEGDYGLSR LSELIKDYTIDKIVLGFPKNMNGTVGPRGEASQTFAKVLETTYNVPVVLWDERLTTMA AEKMLIAADVSRQKRKKVIDKMAAVMILQGYLDSLN*" gene complement(2662997..2663413) /gene="rimF" /locus_tag="BSU_27390" /old_locus_tag="BSU27390" promotor_-10 complement(2663245..2663263) /Source="Nicolas_upshift_promotors" /id="U2111" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.54045954045954" /psig="0.54045954045954" /xcortree=676 /SigmaFactorBS="cataaagataaatgaagcagaaggcgattatggtttatccCG TTTAtctgaactgataaagGACTATACTATAGATAAAAtcgtgctcggctttcctaag a" /listShort="yrzB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2663264) /Source="Nicolas_upshifts" /id="U2111" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.54045954045954" /psig="0.54045954045954" /xcortree=676 /SigmaFactorBS="cataaagataaatgaagcagaaggcgattatggtttatccCG TTTAtctgaactgataaagGACTATACTATAGATAAAAtcgtgctcggctttcctaag a" /listShort="yrzB" /GFF_Attribute="listLong" promotor_-35 complement(2663279..2663284) /Source="Nicolas_upshift_promotors" /id="U2111" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.54045954045954" /psig="0.54045954045954" /xcortree=676 /SigmaFactorBS="cataaagataaatgaagcagaaggcgattatggtttatccCG TTTAtctgaactgataaagGACTATACTATAGATAAAAtcgtgctcggctttcctaag a" /listShort="yrzB" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2663421..2663687) /gene="yrzL" /locus_tag="BSU_27400" /old_locus_tag="BSU27400" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 22333191, 22720735" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="YP_054589.1" /db_xref="EnsemblGenomes-Gn:BSU27400" /db_xref="EnsemblGenomes-Tr:CAE01464" /db_xref="InterPro:IPR009309" /db_xref="SubtiList:BG14184" /db_xref="UniProtKB/Swiss-Prot:Q7WY61" /translation="MSSFDKTMKFNFSDDSAETNVNEVLITVYDALQEKGYNPINQIV GYLLSGDPAYIPRHRDARNLIRKLERDELIEELVKSYLEQHKEA*" gene complement(2663421..2663687) /gene="yrzL" /locus_tag="BSU_27400" /old_locus_tag="BSU27400" promotor_-35 2663575..2663583 /Source="Nicolas_upshift_promotors" /id="U2112" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.99000999000999" /psig="0.99000999000999" /xcortree=1251 /SigmaFactorBS="gcaagtatccgacaatctggttgattggaTTGTAGCCCtttt cctgaagcgcGTCATACACTGTAATCAGCAcctcatttacgttagtctcagcagaatc a" /listShort="S1038" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2663598..2663617 /Source="Nicolas_upshift_promotors" /id="U2112" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.99000999000999" /psig="0.99000999000999" /xcortree=1251 /SigmaFactorBS="gcaagtatccgacaatctggttgattggaTTGTAGCCCtttt cctgaagcgcGTCATACACTGTAATCAGCAcctcatttacgttagtctcagcagaatc a" /listShort="S1038" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 2663606..2664795 /Source="Nicolas_S_feature" /locus_tag="new_2798008_2799197" /HighExp="S6, C30, C90, S8, S7, Gly, G135, Fru, G180, M/G" /AntisenseName="alaS" /AntisenseCor="-0.27843994691040502" /AntisenseRegPval="-5.5" /CDS_PredictionProba="NA" /TUshortSig="SigK" /TUshortPSig="0.99" /TUlongSig="NA" /TUlongPSig="NA" /label="S1038" upshifts 2663606 /Source="Nicolas_upshifts" /id="U2112" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.99000999000999" /psig="0.99000999000999" /xcortree=1251 /SigmaFactorBS="gcaagtatccgacaatctggttgattggaTTGTAGCCCtttt cctgaagcgcGTCATACACTGTAATCAGCAcctcatttacgttagtctcagcagaatc a" /listShort="S1038" /GFF_Attribute="listLong" S_feature complement(2663688..2663748) /Source="Nicolas_S_feature" /locus_tag="new_2798090_2798150_c" /HighExp="LBGtran, LBGexp, G135, C90, G150, G180, LBGstat, Oxctl, LoTm, B60" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigD, SigA" /TUshortPSig="0.994, 0.997, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S1039" promotor_-10 complement(2663742..2663761) /Source="Nicolas_upshift_promotors" /id="U2113" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.57042957042957" /psig="0.994005994005994" /xcortree=3173 /SigmaFactorBS="ggcttctgtagaagattgggtgaaatCCGTTTTAtaattcgc ccatgTAGTGTAGAATGATGGTAAGattaggaccccaggctgaactttgcctgcgaat t" /listShort="S1039, yrzL, yrrK, yrzB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2663748) /Source="Nicolas_upshifts" /id="U2113" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.57042957042957" /psig="0.994005994005994" /xcortree=3173 /SigmaFactorBS="ggcttctgtagaagattgggtgaaatCCGTTTTAtaattcgc ccatgTAGTGTAGAATGATGGTAAGattaggaccccaggctgaactttgcctgcgaat t" /listShort="S1039, yrzL, yrrK, yrzB" /GFF_Attribute="listLong" CDS complement(2663772..2666408) /gene="alaS" /locus_tag="BSU_27410" /old_locus_tag="BSU27410" /EC_number="6.1.1.7" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 12554667, 12682299, 17329819, 22720735, 25918376; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="alanyl-tRNA synthetase" /protein_id="NP_390618.1" /db_xref="EnsemblGenomes-Gn:BSU27410" /db_xref="EnsemblGenomes-Tr:CAB14682" /db_xref="GOA:O34526" /db_xref="InterPro:IPR002318" /db_xref="InterPro:IPR003156" /db_xref="InterPro:IPR009000" /db_xref="InterPro:IPR012947" /db_xref="InterPro:IPR018162" /db_xref="InterPro:IPR018163" /db_xref="InterPro:IPR018164" /db_xref="InterPro:IPR018165" /db_xref="InterPro:IPR023033" /db_xref="SubtiList:BG12563" /db_xref="UniProtKB/Swiss-Prot:O34526" /translation="MKHLTSAEVRQMFLDFFKEKGHAVEPSASLVPHEDPSLLWINSG VATLKKYFDGRVVPENPRIVNAQKAIRTNDIENVGKTARHHTFFEMLGNFSIGDYFKE EAITWAWEFLTSDKWIGFDKELLSVTVHPEDEEAYEFWAKKIGIPEERIIRLEGNFWD IGEGPSGPNTEIFYDRGEAYGNDPEDPELYPGGENDRYLEVWNLVFSEFNHNPDGTYT PLPKKNIDTGMGLERMVSVIQNVPTNFDTDLFVPIIKATESISGETYGKDNVKDTAFK VIADHIRTVAFAVSDGALPSNEGRGYVLRRLLRRAVRYAKTINIHRPFMFDLVPVVAE IMADFYPEVKEKADFIAKVIKTEEERFHETLNEGLAILSEMIKKEKDKGSSVISGADV FKLYDTYGFPVELTEEYAEDENMTVDHEGFEEEMNQQRERARNARQDVGSMQVQGGAL RDVTVESTFVGYSQTKADANIIVLLQDGQLIEEAHEGESVQIILDETPFYAESGGQIG DKGYLRSEQAVVRIKDVQKAPNGQHVHEGVVESGTVQKGLHVTAEVEDHMRSGVIKNH TATHLLHQALKDVLGTHVNQAGSLVTENRLRFDFSHFGQVTKEELEQIERIVNEKIWA SIPVSIDLKPIAEAKEMGAMALFGEKYGDIVRVVQVGDYSLELCGGCHVRNTAEIGLF KIVSESGIGAGTRRIEAVTGQGAYVEMNSQISVLKQTADELKTNIKEVPKRVAALQAE LKDAQRENESLLAKLGNVEAGAILSKVKEVDGVNVLAAKVNAKDMNHLRTMVDELKAK LGSAVIVLGAVQNDKVNISAGVTKDLIEKGLHAGKLVKQAAEVCGGGGGGRPDMAQAG GKQPEKLEEALASVEDWVKSVL*" gene complement(2663772..2666408) /gene="alaS" /locus_tag="BSU_27410" /old_locus_tag="BSU27410" promotor_-35 complement(2663775..2663782) /Source="Nicolas_upshift_promotors" /id="U2113" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.57042957042957" /psig="0.994005994005994" /xcortree=3173 /SigmaFactorBS="ggcttctgtagaagattgggtgaaatCCGTTTTAtaattcgc ccatgTAGTGTAGAATGATGGTAAGattaggaccccaggctgaactttgcctgcgaat t" /listShort="S1039, yrzL, yrrK, yrzB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(2666174..2666192) /Source="Nicolas_upshift_promotors" /id="U2114" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=1639 /SigmaFactorBS="cggccgtgtcgtgccggaaaatccaagaatcgtaaacGCTCA AAAagcgatcagaacaAACGATATAGAAAATGTAGgtaaaactgcgcgccatcacact t" /listShort="S1039, yrzL, yrrK, yrzB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2666190) /Source="Nicolas_upshifts" /id="U2114" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=1639 /SigmaFactorBS="cggccgtgtcgtgccggaaaatccaagaatcgtaaacGCTCA AAAagcgatcagaacaAACGATATAGAAAATGTAGgtaaaactgcgcgccatcacact t" /listShort="S1039, yrzL, yrrK, yrzB" /GFF_Attribute="listLong" promotor_-35 complement(2666206..2666213) /Source="Nicolas_upshift_promotors" /id="U2114" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=1639 /SigmaFactorBS="cggccgtgtcgtgccggaaaatccaagaatcgtaaacGCTCA AAAagcgatcagaacaAACGATATAGAAAATGTAGgtaaaactgcgcgccatcacact t" /listShort="S1039, yrzL, yrrK, yrzB" /GFF_Attribute="listLong" /label="promotor_-35" S_feature complement(2666409..2666487) /Source="Nicolas_S_feature" /locus_tag="new_2800811_2800889_c" /HighExp="G150, LBGexp, G135, G180, Oxctl, LBGtran, Lbexp, Paraq, dia15, H2O2" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1040" misc_RNA complement(2666488..2666695) /gene="tboA" /locus_tag="BSU_misc_RNA_40" /product="T-box riboswitch specific of alanine tRNA" /experiment="publication(s) with functional evidences, PMID:1317842, 9098041, 12165569, 12547201" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1317842, 9098041, 12165569, 12547201; Product type n: RNA" /function="16.3: Control" gene complement(2666488..2666695) /gene="tboA" /locus_tag="BSU_misc_RNA_40" promotor_-10 complement(2666703..2666722) /Source="Nicolas_upshift_promotors" /id="U2115" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.84015984015984" /psig=1 /xcortree=2558 /SigmaFactorBS="aatgatgatccattttttgcggatgaggacggagCATTGACA tcggcgtgccgcttGTCTATAATTTCTCGTAGAAtacatacgaatctcgagtgacgga t" /listShort="NA, S1040, alaS, S1039, yrzL, yrrK, yrzB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2666718) /Source="Nicolas_upshifts" /id="U2115" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.84015984015984" /psig=1 /xcortree=2558 /SigmaFactorBS="aatgatgatccattttttgcggatgaggacggagCATTGACA tcggcgtgccgcttGTCTATAATTTCTCGTAGAAtacatacgaatctcgagtgacgga t" /listShort="NA, S1040, alaS, S1039, yrzL, yrrK, yrzB" /GFF_Attribute="listLong" promotor_-35 complement(2666737..2666744) /Source="Nicolas_upshift_promotors" /id="U2115" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.84015984015984" /psig=1 /xcortree=2558 /SigmaFactorBS="aatgatgatccattttttgcggatgaggacggagCATTGACA tcggcgtgccgcttGTCTATAATTTCTCGTAGAAtacatacgaatctcgagtgacgga t" /listShort="NA, S1040, alaS, S1039, yrzL, yrrK, yrzB" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2666739..2667800) /gene="yrrI" /locus_tag="BSU_27420" /old_locus_tag="BSU27420" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative membrane protein of unknown function" /protein_id="NP_390619.1" /db_xref="EnsemblGenomes-Gn:BSU27420" /db_xref="EnsemblGenomes-Tr:CAB14683" /db_xref="GOA:O34472" /db_xref="InterPro:IPR002549" /db_xref="SubtiList:BG13791" /db_xref="UniProtKB/Swiss-Prot:O34472" /translation="MLQKPVQLLLWVAICLLVLLTVYVFFMLDMLWSPFWLVIKTIFI PLIISIFISYLLLPVTEWLHGKGLPRTLSILVIYVLFFGGIGWALYKGVPVLIVQLTD LSENIPMFAETYNGLLLHVHNHTDDWPDGMHHRIDKMIRQTEAFFAGTIEGAISGIRN VLDYFLIAATIPFLVFYMVKDIELMKKTVWYLTPKSWRKRGSAFLRDVDDSLGDYIRG QLLVCLILGVIAGISFWVFGLPYPLILGLISGVTNVIPYFGPFIGAVPALLIAMTISV KAVLVVVITVFILQFMEGNILSPFIVGRSLKMHPVVIMLALLAGGELAGIVGMILAVP ATAVLKVMMIHFLRMRTEH*" gene complement(2666739..2667800) /gene="yrrI" /locus_tag="BSU_27420" /old_locus_tag="BSU27420" promotor_-35 2667709..2667714 /Source="Nicolas_upshift_promotors" /id="U2116" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1047 /SigmaFactorBS="atcaagggaataaagatcgtttttatgacgagccaaaagggt gaccatAACATAtcaagcataaaaaagACATAGACTGTTAACAGAAccagcaaacaaa t" /listShort="S1041, glnQ, glnH, glnM, glnP" /GFF_Attribute="listLong" /label="promotor_-35" S_feature 2667720..2667955 /Source="Nicolas_S_feature" /locus_tag="new_2802122_2802357" /HighExp="S5, S6, S4, S8, S3, S7, LoTm, BT, M9-stat, T5.0H" /AntisenseName="yrrI" /AntisenseCor="0.71790030040923003" /AntisenseRegPval="-43.2" /CDS_PredictionProba="NA" /TUshortSig="SigEF" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S1041" upshifts 2667721 /Source="Nicolas_upshifts" /id="U2116" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1047 /SigmaFactorBS="atcaagggaataaagatcgtttttatgacgagccaaaagggt gaccatAACATAtcaagcataaaaaagACATAGACTGTTAACAGAAccagcaaacaaa t" /listShort="S1041, glnQ, glnH, glnM, glnP" /GFF_Attribute="listLong" promotor_-10 2667730..2667748 /Source="Nicolas_upshift_promotors" /id="U2116" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1047 /SigmaFactorBS="atcaagggaataaagatcgtttttatgacgagccaaaagggt gaccatAACATAtcaagcataaaaaagACATAGACTGTTAACAGAAccagcaaacaaa t" /listShort="S1041, glnQ, glnH, glnM, glnP" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-10 complement(2667817..2667828) /Source="Nicolas_upshift_promotors" /id="U2117" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.97902097902098" /psig="0.97902097902098" /xcortree=801 /SigmaFactorBS="catgacttctgactgactaaagaaacataaAGAATAAttcct tgtaaaccTCAAAAGATATAggtgaggtgaaagcagatgctccaaaaaccggtgcagc t" /listShort="yrrI" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2667818) /Source="Nicolas_upshifts" /id="U2117" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.97902097902098" /psig="0.97902097902098" /xcortree=801 /SigmaFactorBS="catgacttctgactgactaaagaaacataaAGAATAAttcct tgtaaaccTCAAAAGATATAggtgaggtgaaagcagatgctccaaaaaccggtgcagc t" /listShort="yrrI" /GFF_Attribute="listLong" promotor_-35 complement(2667842..2667848) /Source="Nicolas_upshift_promotors" /id="U2117" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.97902097902098" /psig="0.97902097902098" /xcortree=801 /SigmaFactorBS="catgacttctgactgactaaagaaacataaAGAATAAttcct tgtaaaccTCAAAAGATATAggtgaggtgaaagcagatgctccaaaaaccggtgcagc t" /listShort="yrrI" /GFF_Attribute="listLong" /label="promotor_-35" CDS 2667956..2668684 /gene="glnQ" /locus_tag="BSU_27430" /old_locus_tag="BSU27430" /EC_number="3.6.3.-" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1c: Function from experimental evidences in the studied genus; PubMedId: 1856180; Product type t : transporter" /codon_start=1 /transl_table=11 /product="glutamine ABC transporter (ATP-binding protein)" /protein_id="NP_390620.1" /db_xref="EnsemblGenomes-Gn:BSU27430" /db_xref="EnsemblGenomes-Tr:CAB14684" /db_xref="GOA:O34677" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR017871" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR030679" /db_xref="SubtiList:BG11485" /db_xref="UniProtKB/Swiss-Prot:O34677" /translation="MITFQNVNKHYGDFHVLKQINLQIEKGEVVVIIGPSGSGKSTLL RCINRLESINEGVLTVNGTAINDRKTDINQVRQNIGMVFQHFHLYPHKTVLQNIMLAP VKVLRQSPEQAKETARYYLEKVGIPDKADAYPSQLSGGQQQRVAIARGLAMKPEVMLF DEPTSALDPEMIGEVLDVMKTLAKEGMTMVVVTHEMGFAKEVADRIVFIDEGKILEEA VPAEFYANPKEERARLFLSRILNH*" gene 2667956..2668684 /gene="glnQ" /locus_tag="BSU_27430" /old_locus_tag="BSU27430" downshifts complement(2668412) /Source="Nicolas_upshifts" /id="D1402" /incds=1 /nref=1 /ntot=9 /MaxReadThrough="1.29649" /MaxDrop="3.29152" /score="-3.35464926" /energy="-5.4" /TU="NA" /idTUdmin="U2117" /TUdmin="-726" /isTUend="FALSE" CDS 2668706..2669527 /gene="glnH" /locus_tag="BSU_27440" /old_locus_tag="BSU27440" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1c: Function from experimental evidences in the studied genus; PubMedId: 1856180; Product type lp : lipoprotein" /codon_start=1 /transl_table=11 /product="glutamine ABC transporter (glutamine-binding lipoprotein)" /protein_id="NP_390621.1" /db_xref="EnsemblGenomes-Gn:BSU27440" /db_xref="EnsemblGenomes-Tr:CAB14685" /db_xref="GOA:O34563" /db_xref="InterPro:IPR001320" /db_xref="InterPro:IPR001638" /db_xref="InterPro:IPR018313" /db_xref="SubtiList:BG11486" /db_xref="UniProtKB/Swiss-Prot:O34563" /translation="MKKIFSLALISLFAVILLAACGSKGSNGEASKESKKDTLAAIKD NDKIVFGVKTDTRLFGLKNPSSGEIEGFDIDIAKQIAKDILGDEKKAQFKEVTSKTRI PMLQNGDIDAIVATMTITEERKKEVDFSDVYFEAGQSLLVKKGSKIKSVENLGKGSKV LAVKGSTSSQNIREKAPEASVLEFENYAEAFTALKSGQGDALTTDNAILYGMADENKN YQLTGKPFTDEPYGIAVKKGQSALAKEINASLKKMKSDGRYDEIYKKWIKEDPAE*" gene 2668706..2669527 /gene="glnH" /locus_tag="BSU_27440" /old_locus_tag="BSU27440" CDS 2669588..2670238 /gene="glnM" /locus_tag="BSU_27450" /old_locus_tag="BSU27450" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1c: Function from experimental evidences in the studied genus; PubMedId: 1856180, 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="glutamine ABC transporter (permease)" /protein_id="NP_390622.1" /db_xref="EnsemblGenomes-Gn:BSU27450" /db_xref="EnsemblGenomes-Tr:CAB14686" /db_xref="GOA:O34671" /db_xref="InterPro:IPR000515" /db_xref="InterPro:IPR010065" /db_xref="InterPro:IPR035906" /db_xref="SubtiList:BG11487" /db_xref="UniProtKB/Swiss-Prot:O34671" /translation="MNVSILFDNFSMYMDGFYHTLLASVIALAGSFVLGVAVAVMRIT VFKPLQWLGTAYVEFIRNIPLLLITFVFYFGLPNAGLRLDGFQAGTVALTIYTSAFIA EAIRAGIQSVSKGQMEAARSSGFTYSQAMLHIILPQAIKIVIPPLGNQFLNLVKNSSI LGVVAGLDLMYQADLVSSSTLVVFDVYIFVALFYLVLTIPLSIGVNYLEKRLEKSY*" gene 2669588..2670238 /gene="glnM" /locus_tag="BSU_27450" /old_locus_tag="BSU27450" CDS 2670255..2670911 /gene="glnP" /locus_tag="BSU_27460" /old_locus_tag="BSU27460" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1c: Function from experimental evidences in the studied genus; PubMedId: 1856180, 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="glutamine ABC transporter (permease)" /protein_id="NP_390623.1" /db_xref="EnsemblGenomes-Gn:BSU27460" /db_xref="EnsemblGenomes-Tr:CAB14687" /db_xref="GOA:O34606" /db_xref="InterPro:IPR000515" /db_xref="InterPro:IPR010065" /db_xref="InterPro:IPR035906" /db_xref="SubtiList:BG11488" /db_xref="UniProtKB/Swiss-Prot:O34606" /translation="MDFIGAYSQEHLAFLWDGFLVTLYVAFISIILSFFFGLIAGTLR YAKVPVLSQLIAVLVETIRNLPLLLIIFFTFFALPEIGIKLEITAAAITALTIFESAM LSEIIRSGLKSIDKGQIEAARSSGLSYTQTLFFIVMPQALRRMVPPIVSQFISLLKDT SLAVVIALPELIHNAQIINGQSADGSYFFPIFLLAALMYFAVNYSLSLAARRLEVRQT *" gene 2670255..2670911 /gene="glnP" /locus_tag="BSU_27460" /old_locus_tag="BSU27460" downshifts 2670910 /Source="Nicolas_upshifts" /id="D1403" /incds=0 /nref=15 /ntot=32 /MaxReadThrough="2.21558" /MaxDrop="6.08472" /score="5.38937989" /energy="-11.7" /TU="NA" /idTUdmin="U2116" /TUdmin=0 /isTUend="TRUE" CDS complement(2670946..2671077) /gene="yrzQ" /locus_tag="BSU_27468" /old_locus_tag="BSU27468" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="YP_003097766.1" /db_xref="EnsemblGenomes-Gn:BSU27468" /db_xref="EnsemblGenomes-Tr:CAX52672" /db_xref="InterPro:IPR025029" /db_xref="UniProtKB/Swiss-Prot:C0H461" /translation="MNRTMTSLLAMGAGALVYRMATQSDMLNNRSMKRMRRRITKMF* " gene complement(2670946..2671077) /gene="yrzQ" /locus_tag="BSU_27468" /old_locus_tag="BSU27468" downshifts complement(2670964) /Source="Nicolas_upshifts" /id="D1404" /incds=0 /nref=50 /ntot=77 /MaxReadThrough="1.58565" /MaxDrop="8.21989" /score="5.69801689" /energy="-11.7" /TU="NA" /idTUdmin="U2118" /TUdmin=0 /isTUend="TRUE" CDS complement(2671099..2671290) /gene="yrzR" /locus_tag="BSU_27469" /old_locus_tag="BSU27469" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="YP_003097767.1" /db_xref="EnsemblGenomes-Gn:BSU27469" /db_xref="EnsemblGenomes-Tr:CAX52673" /db_xref="UniProtKB/Swiss-Prot:C0H462" /translation="MLICPNCKSKDIGKIGVNQYYCWGCFIELTVAKGKIATHQVEED GTLSSLDDLFSEDERSINF*" gene complement(2671099..2671290) /gene="yrzR" /locus_tag="BSU_27469" /old_locus_tag="BSU27469" CDS complement(2671302..2671826) /gene="yrrD" /locus_tag="BSU_27470" /old_locus_tag="BSU27470" /function="18: Unknown function" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_390624.1" /db_xref="EnsemblGenomes-Gn:BSU27470" /db_xref="EnsemblGenomes-Tr:CAB14688" /db_xref="InterPro:IPR011033" /db_xref="InterPro:IPR027275" /db_xref="SubtiList:BG13790" /db_xref="UniProtKB/Swiss-Prot:O34402" /translation="MSLRRKAKPKPVQQKVVDHTLRTCHEVEGFPVYSERTSSYLGTI SDICFSLKGDCLGFILAQKRFLHHHHALLRACDISSIFDDRILASVSSEQLLPLPKSC FTYEQMKMKLVKSQEGDILGMLEDVYFCLDRGIIVAYELSDGFFSDLAGSKRQIQRAD SLVEVRKDEIVLNG*" gene complement(2671302..2671826) /gene="yrrD" /locus_tag="BSU_27470" /old_locus_tag="BSU27470" upshifts complement(2671413) /Source="Nicolas_upshifts" /id="U2118" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.84015984015984" /psig="0.84015984015984" /xcortree=827 /SigmaFactorBS="ggatatattggggatgctggaagaTGTATACttttgtttgga cagGGGCATAATCGTagcatatgaactctcggacggtttcttttctgacctggcggga a" /listShort="yrzR, yrzQ" /GFF_Attribute="listLong" promotor_-10 complement(2671417..2671428) /Source="Nicolas_upshift_promotors" /id="U2118" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.84015984015984" /psig="0.84015984015984" /xcortree=827 /SigmaFactorBS="ggatatattggggatgctggaagaTGTATACttttgtttgga cagGGGCATAATCGTagcatatgaactctcggacggtttcttttctgacctggcggga a" /listShort="yrzR, yrzQ" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 complement(2671443..2671449) /Source="Nicolas_upshift_promotors" /id="U2118" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.84015984015984" /psig="0.84015984015984" /xcortree=827 /SigmaFactorBS="ggatatattggggatgctggaagaTGTATACttttgtttgga cagGGGCATAATCGTagcatatgaactctcggacggtttcttttctgacctggcggga a" /listShort="yrzR, yrzQ" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(2671797..2671808) /Source="Nicolas_upshift_promotors" /id="U2119" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=838 /SigmaFactorBS="agttttttttcatttgcagtggaattgatttcatCGTATGAg tctaaggcgcaaaGCAAAACCTAAGcctgttcaacaaaaggtggttgatcacactttg a" /listShort="yrrD, yrzR, yrzQ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2671803) /Source="Nicolas_upshifts" /id="U2119" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=838 /SigmaFactorBS="agttttttttcatttgcagtggaattgatttcatCGTATGAg tctaaggcgcaaaGCAAAACCTAAGcctgttcaacaaaaggtggttgatcacactttg a" /listShort="yrrD, yrzR, yrzQ" /GFF_Attribute="listLong" promotor_-35 complement(2671823..2671829) /Source="Nicolas_upshift_promotors" /id="U2119" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=838 /SigmaFactorBS="agttttttttcatttgcagtggaattgatttcatCGTATGAg tctaaggcgcaaaGCAAAACCTAAGcctgttcaacaaaaggtggttgatcacactttg a" /listShort="yrrD, yrzR, yrzQ" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2671884..2674280) /gene="recDB" /locus_tag="BSU_27480" /old_locus_tag="BSU27480" /EC_number="3.1.11.5" /function="16.9: Replicate" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:3537961, 11557815, 21170359, 22720735, 24443534, 28527403" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 3537961, 11557815, 21170359, 22720735, 24443534, 28527403; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="5'-3' helicase associated to SSB; exonuclease V" /protein_id="NP_390625.1" /db_xref="EnsemblGenomes-Gn:BSU27480" /db_xref="EnsemblGenomes-Tr:CAB14689" /db_xref="GOA:O34481" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR006345" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR027785" /db_xref="InterPro:IPR029493" /db_xref="SubtiList:BG13789" /db_xref="UniProtKB/Swiss-Prot:O34481" /translation="MQQHPDQLKLEEEPYLKGTVNTVIYHNDTNLYTVLKVKVTETSE AIEDKAVSVTGYFPALQEEETYTFYGKIVTHPKFGLQFQAEHFKKEIPTTKEGIIQYL SSDLFEGIGKKTAEEIVKKLGDSAINKILADASVLYDVPRLSKKKADTLAGALQRHQG LEQIMISLNQFGFGPQLSMKIYQAYESETLEKIQENPYQLVKDVEGIGFGKADELGSR MGLSGNHPERVKAAILYTLETTCLSEGHTYIETEQLIIDTQSLLNQSAREGQRITEMD AANAIIALGENKDIVIEDGRCYFPSLFYAEQNVAKRVKHIASQTEYENQFPESEFLLA LGELEERMDVQYAPSQKEAIQKALSSPMLLLTGGPGTGKTTVIRGIVELYGELHGVSL DPSAYKKDEAFPIVLAAPTGRAAKRMSESTGLPAVTIHRLLGWNGAEGFTHTEDQPIE GKLLIIDEASMLDIWLANHLFKAIPDHIQIIIVGDEDQLPSVGPGQVLRDLLASQVIP TVRLTDIYRQAEGSSIVELAHQMKNGLLPNNLTAPTKDRSFIRCGGSQIKEVVEKVVA NALKKGYTAKDIQVLAPMYRGKAGINELNVMLQDILNPPKEKRRELKFGDVVYRTGDK ILQLVNQPENNVFNGDIGEITSIFYAKENTEKEDMAVVSFDGNEMTFTKKDFNQFTHA YCCSIHKSQGSEFPIVVLPVVKGYYRMLRRNLLYTAITRAKKFLILCGEEEALEWGVK NNDATVRQTSLKNRLSVQVEEMDAELEALQKELPFSVHDANIGMEGITPFDFMKEEQQ *" gene complement(2671884..2674280) /gene="recDB" /locus_tag="BSU_27480" /old_locus_tag="BSU27480" downshifts complement(2671910) /Source="Nicolas_upshifts" /id="D1405" /incds=0 /nref=32 /ntot=211 /MaxReadThrough="2.07603" /MaxDrop="3.57113" /score="41.0323102" /energy="-10.8" /TU="NA" /idTUdmin="U2121" /TUdmin=0 /isTUend="TRUE" promotor_-35 2672130..2672136 /Source="Nicolas_upshift_promotors" /id="U2120" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=884 /SigmaFactorBS="cctcttccccgcataaaatgagaaatttcttcgctcttgtaa tcgcGGTATAAagaaggtttcttctGAGCATTCTATAatagcctttcacaacaggcaa a" /listShort="S1042" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 2672144 /Source="Nicolas_upshifts" /id="U2120" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=884 /SigmaFactorBS="cctcttccccgcataaaatgagaaatttcttcgctcttgtaa tcgcGGTATAAagaaggtttcttctGAGCATTCTATAatagcctttcacaacaggcaa a" /listShort="S1042" /GFF_Attribute="listLong" promotor_-10 2672151..2672162 /Source="Nicolas_upshift_promotors" /id="U2120" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=884 /SigmaFactorBS="cctcttccccgcataaaatgagaaatttcttcgctcttgtaa tcgcGGTATAAagaaggtttcttctGAGCATTCTATAatagcctttcacaacaggcaa a" /listShort="S1042" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 2672164..2672513 /Source="Nicolas_S_feature" /locus_tag="new_2806566_2806915" /HighExp="S8, S5, S6, S7, S4, C30, nit, ferm, G135, T5.0H" /AntisenseName="yrrC" /AntisenseCor="-0.46935785055870999" /AntisenseRegPval="-15.4" /CDS_PredictionProba="NA" /TUshortSig="SigGF" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1042" downshifts complement(2672265) /Source="Nicolas_upshifts" /id="D1406" /incds=1 /nref=16 /ntot=163 /MaxReadThrough="4.93428" /MaxDrop="2.86437" /score="41.0323102" /energy="-10.8" /TU="U2121,U2122" /idTUdmin="U2121" /TUdmin="-355" /isTUend="FALSE" CDS complement(2674305..2674925) /gene="yrrB" /locus_tag="BSU_27490" /old_locus_tag="BSU27490" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 11777911, 12594026, 18180259; Product type f: factor" /codon_start=1 /transl_table=11 /product="putative tetratricopeptide repeat family protein" /protein_id="NP_390626.1" /db_xref="EnsemblGenomes-Gn:BSU27490" /db_xref="EnsemblGenomes-Tr:CAB14690" /db_xref="InterPro:IPR011990" /db_xref="InterPro:IPR013026" /db_xref="InterPro:IPR013105" /db_xref="InterPro:IPR019734" /db_xref="PDB:2Q7F" /db_xref="SubtiList:BG13788" /db_xref="UniProtKB/Swiss-Prot:O34452" /translation="MQEGDYEKAAEAFTKAIEENKEDAIPYINFANLLSSVNELERAL AFYDKALELDSSAATAYYGAGNVYVVKEMYKEAKDMFEKALRAGMENGDLFYMLGTVL VKLEQPKLALPYLQRAVELNENDTEARFQFGMCLANEGMLDEALSQFAAVTEQDPGHA DAFYNAGVTYAYKENREKALEMLDKAIDIQPDHMLALHAKKLIDPS*" gene complement(2674305..2674925) /gene="yrrB" /locus_tag="BSU_27490" /old_locus_tag="BSU27490" CDS complement(2675011..2676126) /gene="mnmA" /locus_tag="BSU_27500" /old_locus_tag="BSU27500" /EC_number="2.8.1.13" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:12549933, 12756333, 9811540, 15044829, 17580114, 22720735, 25825430" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12549933, 12756333, 9811540, 15044829, 17580114, 22720735, 25825430; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="tRNA-specific 2-thiouridylase" /protein_id="NP_390627.3" /db_xref="EnsemblGenomes-Gn:BSU27500" /db_xref="EnsemblGenomes-Tr:CAB14691" /db_xref="GOA:O35020" /db_xref="InterPro:IPR004506" /db_xref="InterPro:IPR014729" /db_xref="InterPro:IPR023382" /db_xref="SubtiList:BG13787" /db_xref="UniProtKB/Swiss-Prot:O35020" /translation="MEKRPEDTRVVVGMSGGVDSSVAALLLKEQGYDVIGIFMKNWDD TDENGFCTATEDYEDVIRVCNQIGIPYYAVNFEKQYYEKVFQYFLDEYKAGRTPNPDV LCNKEIKFKAFLEHALSLGADYLATGHYARVDRSGGKVRMLRGIDENKDQTYFLNQLT EDTLSKVMFPIGELQKSRVREIAKEAELATATKKDSTGICFIGERNFKTFLSQYLPAQ PGDMMTMDGEVKGRHDGLMYYTIGQRHGLGIGGSGEPWFAVGKDLEKNILYVDQGFHN PLLYSDKITATNISWVRSDIMKGEEISCTAKFRYRQEDHKVTVRMTGEGEAEVIFDEQ VRAVTPGQAVVFYDGEECLGGGTIDDVYKDGTKLWYV*" gene complement(2675011..2676126) /gene="mnmA" /locus_tag="BSU_27500" /old_locus_tag="BSU27500" downshifts complement(2675012) /Source="Nicolas_upshifts" /id="D1407" /incds=0 /nref=2 /ntot=69 /MaxReadThrough="6.45399" /MaxDrop="4.31641" /score="2.49091848" /energy="-7.8" /TU="U2121,U2122" /idTUdmin="U2121" /TUdmin="-3102" /isTUend="FALSE" CDS complement(2676157..2677296) /gene="iscSA" /locus_tag="BSU_27510" /old_locus_tag="BSU27510" /EC_number="2.8.1.7" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:7496536, 10930739, 12682299, 17064282, 25825430" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7496536, 10930739, 12682299, 17064282, 25825430; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="cysteine desulfurase involved in U34 tRNA thiolation" /protein_id="NP_390629.2" /db_xref="EnsemblGenomes-Gn:BSU27510" /db_xref="EnsemblGenomes-Tr:CAB14693" /db_xref="GOA:O34599" /db_xref="InterPro:IPR000192" /db_xref="InterPro:IPR015421" /db_xref="InterPro:IPR015422" /db_xref="InterPro:IPR015424" /db_xref="InterPro:IPR016454" /db_xref="InterPro:IPR020578" /db_xref="SubtiList:BG13809" /db_xref="UniProtKB/Swiss-Prot:O34599" /translation="MERIYLDHAATSPMDERVLEQMIPHFSGSFGNPSSIHSFGRESR KWVDEARAQIAAEIGAAEQEIIFTSGGTEADNLAIMGTALARKDLGRHIITTKIEHHA VLHTCEKLEGDGFDITYLDVDQNGRVSAKQVKEALRDDTILVTVMYGNNEVGTVQPIE EIGELLKEHKAYFHTDAVQAFGLLPIDVKNSHIDLLSVSGHKLNGPKGTGFLYASKDV KLSPLLFGGEQERKRRAGTENVPGIVGLKEAIKLSSEERDEKNEKYQSFKAIFADTLR DAGVAFEVNGDKEHSLPHVLNLYFPGVSVEALLVNLDMAGVAVSSGSACTAGSVLPSH VLTAMFGEESDRLTSSIRISFGLGNTAEQVKTAAKHVADVVKRLT*" gene complement(2676157..2677296) /gene="iscSA" /locus_tag="BSU_27510" /old_locus_tag="BSU27510" promotor_-10 complement(2676863..2676882) /Source="Nicolas_upshift_promotors" /id="U2121" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.687312687312687" /psig="0.978021978021978" /xcortree=2070 /SigmaFactorBS="acgttgaccaaaatggaagagtcagtgcaaaaCAGGTGAAag aagcactgcgtGATGATACAATCCTTGTGACagtgatgtatggaaataatgaagtcgg a" /listShort="trmU, yrrB, yrrC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2676875) /Source="Nicolas_upshifts" /id="U2121" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.687312687312687" /psig="0.978021978021978" /xcortree=2070 /SigmaFactorBS="acgttgaccaaaatggaagagtcagtgcaaaaCAGGTGAAag aagcactgcgtGATGATACAATCCTTGTGACagtgatgtatggaaataatgaagtcgg a" /listShort="trmU, yrrB, yrrC" /GFF_Attribute="listLong" promotor_-35 complement(2676896..2676903) /Source="Nicolas_upshift_promotors" /id="U2121" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.687312687312687" /psig="0.978021978021978" /xcortree=2070 /SigmaFactorBS="acgttgaccaaaatggaagagtcagtgcaaaaCAGGTGAAag aagcactgcgtGATGATACAATCCTTGTGACagtgatgtatggaaataatgaagtcgg a" /listShort="trmU, yrrB, yrrC" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2677315..2677731) /gene="cymR" /locus_tag="BSU_27520" /old_locus_tag="BSU27520" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:15668000, 16109943, 16513748, 17056751, 18974048, 19508281, 21624051" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15668000, 16109943, 16513748, 17056751, 18974048, 19508281, 21624051; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator of cysteine biosynthesis" /protein_id="NP_390630.2" /db_xref="EnsemblGenomes-Gn:BSU27520" /db_xref="EnsemblGenomes-Tr:CAB14694" /db_xref="GOA:O34527" /db_xref="InterPro:IPR000944" /db_xref="InterPro:IPR030489" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="PDB:2Y75" /db_xref="SubtiList:BG13813" /db_xref="UniProtKB/Swiss-Prot:O34527" /translation="MKISTKGRYGLTIMIELAKKHGEGPTSLKSIAQTNNLSEHYLEQ LVSPLRNAGLVKSIRGAYGGYVLGSEPDAITAGDIIRVLEGPISPVEVLEDEEPAKRE LWIRIRDAVKEVLDSTTLEDLASYTDGEQEAYMFYI*" gene complement(2677315..2677731) /gene="cymR" /locus_tag="BSU_27520" /old_locus_tag="BSU27520" S_feature complement(2677732..2677829) /Source="Nicolas_S_feature" /locus_tag="new_2812134_2812231_c" /HighExp="Cold, T3.0H, G135, LBGexp, G180, G150, Salt, Lbexp, H2O2, T5.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1043" promotor_-10 complement(2677814..2677833) /Source="Nicolas_upshift_promotors" /id="U2122" /multdbtbs="SigA" /comp="M16" /sig="SigA" /pcomp="0.932067932067932" /psig=1 /xcortree=2578 /SigmaFactorBS="cattagaaaagggtaaaggcccctttccttctgcctcAATGa aaattcgctgaaggTATGTTATAATAACAGTTGGtctataagataataaacggacgaa a" /listShort="S1043, cymR, iscS, trmU, yrrB, yrrC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2677829) /Source="Nicolas_upshifts" /id="U2122" /multdbtbs="SigA" /comp="M16" /sig="SigA" /pcomp="0.932067932067932" /psig=1 /xcortree=2578 /SigmaFactorBS="cattagaaaagggtaaaggcccctttccttctgcctcAATGa aaattcgctgaaggTATGTTATAATAACAGTTGGtctataagataataaacggacgaa a" /listShort="S1043, cymR, iscS, trmU, yrrB, yrrC" /GFF_Attribute="listLong" promotor_-35 complement(2677849..2677852) /Source="Nicolas_upshift_promotors" /id="U2122" /multdbtbs="SigA" /comp="M16" /sig="SigA" /pcomp="0.932067932067932" /psig=1 /xcortree=2578 /SigmaFactorBS="cattagaaaagggtaaaggcccctttccttctgcctcAATGa aaattcgctgaaggTATGTTATAATAACAGTTGGtctataagataataaacggacgaa a" /listShort="S1043, cymR, iscS, trmU, yrrB, yrrC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 2677877..2677884 /Source="Nicolas_upshift_promotors" /id="U2123" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.974025974025974" /psig=1 /xcortree=1971 /SigmaFactorBS="tttcattgaggcagaaggaaaggggcctttaCCCTTTTCtaa tgtacggtttTCCGTTACCCTGTAATTAAGtaaggagagatgatagatgaagccattg g" /listShort="yrvN" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2677898..2677917 /Source="Nicolas_upshift_promotors" /id="U2123" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.974025974025974" /psig=1 /xcortree=1971 /SigmaFactorBS="tttcattgaggcagaaggaaaggggcctttaCCCTTTTCtaa tgtacggtttTCCGTTACCCTGTAATTAAGtaaggagagatgatagatgaagccattg g" /listShort="yrvN" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2677906 /Source="Nicolas_upshifts" /id="U2123" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.974025974025974" /psig=1 /xcortree=1971 /SigmaFactorBS="tttcattgaggcagaaggaaaggggcctttaCCCTTTTCtaa tgtacggtttTCCGTTACCCTGTAATTAAGtaaggagagatgatagatgaagccattg g" /listShort="yrvN" /GFF_Attribute="listLong" CDS 2677934..2679199 /gene="rarA" /locus_tag="BSU_27530" /old_locus_tag="BSU27530" /function="16.3: Control" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:15743409, 17641684, 21170359" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15743409, 17641684, 21170359; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="DNA-dependent ATPase active at replication forks" /protein_id="NP_390631.1" /db_xref="EnsemblGenomes-Gn:BSU27530" /db_xref="EnsemblGenomes-Tr:CAB14695" /db_xref="GOA:O34528" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR008824" /db_xref="InterPro:IPR008921" /db_xref="InterPro:IPR021886" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR032423" /db_xref="SubtiList:BG13808" /db_xref="UniProtKB/Swiss-Prot:O34528" /translation="MKPLAYRMRPTKIEDIIGQQHLVAEDKIIGRMVQAKHLSSMILY GPPGIGKTSIATAIAGSTSIAFRKLNAVINNKKDMEIVAQEAKMSGQVILILDEVHRL DKGKQDFLLPYLENGMIILIGATTANPYHAINPAIRSRTQIFELEPLTPELIKQALER ALHDEHRGLGTYSVSIDDQAMEHFAHGCGGDVRSALNALELAVLSTKESADGEIHITL ETAEECLQKKSFSHDKDGDAHYDVLSAFQKSIRGSDANAALHYLARLIEAGDLESIAR RLLVIAYEDIGLASPQAGPRVLNAIQTAERVGFPEARIPLANAVIELCLSPKSNSAIL AIDEALADIRAGKIGDVPKHLKDAHYKGAQELGRGIDYKYPHNYDNGWVEQQYLPDPL KNKQYYKPKQTGKFESALKQVYDKLMKRK*" gene 2677934..2679199 /gene="rarA" /locus_tag="BSU_27530" /old_locus_tag="BSU27530" downshifts 2679198 /Source="Nicolas_upshifts" /id="D1408" /incds=0 /nref=24 /ntot=228 /MaxReadThrough="1.09429" /MaxDrop="4.5261" /score="14.6665846" /energy="-12" /TU="NA" /idTUdmin="U2123" /TUdmin="-7" /isTUend="TRUE" CDS complement(2679241..2680005) /gene="tcdA" /locus_tag="BSU_27540" /old_locus_tag="BSU27540" /EC_number="6.1.-.-" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 12177353, 20097860, 23242255, 27913733, 28671653; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="tRNA threonylcarbamoyladenosine dehydratase (t(6)A37 dehydratase)" /protein_id="NP_390632.3" /db_xref="EnsemblGenomes-Gn:BSU27540" /db_xref="EnsemblGenomes-Tr:CAB14713" /db_xref="GOA:O32037" /db_xref="InterPro:IPR000594" /db_xref="InterPro:IPR035985" /db_xref="SubtiList:BG13807" /db_xref="UniProtKB/Swiss-Prot:O32037" /translation="MLHQFSRNELAIGKEGLETLKNSTVAVLGVGGVGSFAAEALARS GVGRILLVDKDDVDITNVNRQLHALLSTVGQPKVDLMKARIADINPECEVIALKMFYT EETYEQFFDYGLDYVIDASDTICYKIHLMKECLKRDIPLISSMGAANKTDPTRFQIAD ISKTHTDPIAKVVRTKLRKEGIKKGVQVIFSDESPIVIREDVRKEVGNDEAKIRKAKM PPSSNAFVPSVAGLIMGGHVVMDLLKDIEIKRVKDK*" gene complement(2679241..2680005) /gene="tcdA" /locus_tag="BSU_27540" /old_locus_tag="BSU27540" downshifts complement(2679259) /Source="Nicolas_upshifts" /id="D1409" /incds=0 /nref=246 /ntot=264 /MaxReadThrough="2.35294" /MaxDrop="7.20309" /score="44.7253801" /energy="-12" /TU="NA" /idTUdmin="U2125" /TUdmin=0 /isTUend="TRUE" misc_RNA complement(2680089..2680289) /gene="ssrSB" /locus_tag="BSU_misc_RNA_41" /product="6Sb RNA" /experiment="publication(s) with functional evidences, PMID:12177353, 15793584, 15811922, 25576829, 26873600" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12177353, 15793584, 15811922, 25576829, 26873600; Product type n: RNA" gene complement(2680089..2680289) /gene="ssrSB" /locus_tag="BSU_misc_RNA_41" downshifts complement(2680107) /Source="Nicolas_upshifts" /id="D1410" /incds=0 /nref=81 /ntot=303 /MaxReadThrough="7.44881" /MaxDrop="6.73892" /score="44.7253801" /energy="-12" /TU="U2125,U2127" /idTUdmin="U2125" /TUdmin="-848" /isTUend="FALSE" upshifts 2680276 /Source="Nicolas_upshifts" /id="U2124" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.425574425574426" /psig="0.143856143856144" /xcortree=714 /SigmaFactorBS="gcgggctcccaaatcaaaaaaatgttcggtcaaaactaggtg tacaactaacacatcaggaCTTTATTTAActtgtcaaaatcatatcacagacgatttt g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" misc_feature 2680277..2680286 /Source="Nicolas_upshift_promotors" /id="U2124" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.425574425574426" /psig="0.143856143856144" /xcortree=714 /SigmaFactorBS="gcgggctcccaaatcaaaaaaatgttcggtcaaaactaggtg tacaactaacacatcaggaCTTTATTTAActtgtcaaaatcatatcacagacgatttt g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" promotor_-10 complement(2680287..2680306) /Source="Nicolas_upshift_promotors" /id="U2125" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.578421578421578" /psig=1 /xcortree=392 /SigmaFactorBS="aaaaaagttaagaactgaatttgcagttcgatTCTTGAAAat caaaatcgtcTGTGATATGATTTTGACAAGttaaataaagtcctgatgtgttagttgt a" /listShort="NA, yrvM" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2680298) /Source="Nicolas_upshifts" /id="U2125" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.578421578421578" /psig=1 /xcortree=392 /SigmaFactorBS="aaaaaagttaagaactgaatttgcagttcgatTCTTGAAAat caaaatcgtcTGTGATATGATTTTGACAAGttaaataaagtcctgatgtgttagttgt a" /listShort="NA, yrvM" /GFF_Attribute="listLong" promotor_-35 complement(2680319..2680326) /Source="Nicolas_upshift_promotors" /id="U2125" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.578421578421578" /psig=1 /xcortree=392 /SigmaFactorBS="aaaaaagttaagaactgaatttgcagttcgatTCTTGAAAat caaaatcgtcTGTGATATGATTTTGACAAGttaaataaagtcctgatgtgttagttgt a" /listShort="NA, yrvM" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2680341..2682119) /gene="aspS" /locus_tag="BSU_27550" /old_locus_tag="BSU27550" /EC_number="6.1.1.12" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:12177353, 26804570" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12177353, 26804570; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="aspartyl-tRNA synthetase, promiscuous (also recognizes tRNAasn)" /protein_id="NP_390633.1" /db_xref="EnsemblGenomes-Gn:BSU27550" /db_xref="EnsemblGenomes-Tr:CAB14714" /db_xref="GOA:O32038" /db_xref="InterPro:IPR002312" /db_xref="InterPro:IPR004115" /db_xref="InterPro:IPR004364" /db_xref="InterPro:IPR004365" /db_xref="InterPro:IPR004524" /db_xref="InterPro:IPR006195" /db_xref="InterPro:IPR012340" /db_xref="InterPro:IPR029351" /db_xref="SubtiList:BG12572" /db_xref="UniProtKB/Swiss-Prot:O32038" /translation="MFGRTYYCGDITEKAIGESVTLKGWVQKRRDLGGLIFIDLRDRT GIVQVVFNPDVSKEALAIAEGIRNEYVLDIQGKVVAREEGTVNPNLKTGAIEIHADGV NVLNAAKTPPFAISDQAEEVSEDVRLKHRYLDLRRPAMFQTMQLRHNVTKAVRSFLDE NGFLDIETPILTGSTPEGARDYLVPSRVHEGEFYALPQSPQLFKQLLMVSGIERYYQI ARCFRDEDLRADRQPEFTQIDIEMSFMSQEDIMSLAEEMMAKVMRETKGEELQLPLPR MTYDEAMNKYGSDKPDTRFDMLLTDVSDIVKDTEFKVFSSAVANGGVVKAINVKGGAG DYSRKDIDALGAFAANYGAKGLAWVKVEADGVKGPIAKFFDEEKQSKLIEALDAAEGD LLLFGADQFEVVAASLGALRLKLGKERGLIDEKLFNFLWVIDWPLLEHDPEEGRFYAA HHPFTMPVREDLELIETAPEDMKAQAYDLVLNGYELGGGSIRIFEKDIQEKMFALLGF SPEEAAEQFGFLLEAFEYGAPPHGGIALGLDRLVMLLAGRTNLRDTIAFPKTASASCL MTEAPGEVSDAQLDELHLSIKKKVKN*" gene complement(2680341..2682119) /gene="aspS" /locus_tag="BSU_27550" /old_locus_tag="BSU27550" CDS complement(2682133..2683407) /gene="hisS" /locus_tag="BSU_27560" /old_locus_tag="BSU27560" /EC_number="6.1.1.21" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 28321488; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="histidyl-tRNA synthetase" /protein_id="NP_390634.1" /db_xref="EnsemblGenomes-Gn:BSU27560" /db_xref="EnsemblGenomes-Tr:CAB14715" /db_xref="GOA:O32039" /db_xref="InterPro:IPR004154" /db_xref="InterPro:IPR004516" /db_xref="InterPro:IPR006195" /db_xref="InterPro:IPR015807" /db_xref="InterPro:IPR033656" /db_xref="InterPro:IPR036621" /db_xref="SubtiList:BG12605" /db_xref="UniProtKB/Swiss-Prot:O32039" /translation="MGYNIPRGTQDILPGESDRWQFVEQIMRDTCRTYQYKEIRTPIF EHTELFARGVGESTDIVQKEMYTFEDRKGRSLTLRPEGTAAAVRAFNENKLFANPVQP TKLYYVGPMFRYERPQTGRYRQFYQFGIEAIGSKDPAIDAEVMALAMSIYEKAGLENV KLVINSLGDQDSRKSYREALVKHFEPRIEEFCSDCQSRLHTNPLRILDCKKDRDHELM KSAPSILTYLNEESAAYFEKVKQYLNDLGISYEIDPNLVRGLDYYNHTAFEIMSNAEG FGAITTLAGGGRYDGLVEQIGGPEAPGIGFAMSIERLLAAIDAEKRELPVDKGIDCYI VTLGEKAKDYSVSLVYKLREAGISSEIDYENKKMKGQFKTADRLKARFIAILGEDELA QNKINVKDAQTGEQIEVALDEFIHVMKANQKG*" gene complement(2682133..2683407) /gene="hisS" /locus_tag="BSU_27560" /old_locus_tag="BSU27560" misc_RNA complement(2683497..2683729) /gene="tboH" /locus_tag="BSU_misc_RNA_42" /product="T-box riboswitch controlling synthesis of histidine and aspartate tRNA ligases" /note="Evidence 1a: Function from experimental evidences in the studied strain; Product type n: RNA" /function="16.3: Control" gene complement(2683497..2683729) /gene="tboH" /locus_tag="BSU_misc_RNA_42" downshifts complement(2683527) /Source="Nicolas_upshifts" /id="D1411" /incds=0 /nref=71 /ntot=180 /MaxReadThrough="7.0761" /MaxDrop="5.61082" /score="40.6097692" /energy="-23.7" /TU="U2127" /idTUdmin="U2128" /TUdmin=0 /isTUend="TRUE" promotor_-35 2683739..2683742 /Source="Nicolas_upshift_promotors" /id="U2126" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.582417582417582" /psig=1 /xcortree=2538 /SigmaFactorBS="ctgacctactcttctccattattggttcaaatctttcatcAT TTgctatgtactcaatTTCTATTATAATAATGGGATtggggttctctgtcaagcttta t" /listShort="S1044, yrvJ" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(2683753..2683772) /Source="Nicolas_upshift_promotors" /id="U2127" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.9000999000999" /psig=1 /xcortree=3008 /SigmaFactorBS="ccaaagaagcagcgctgaggaaaaacaaccggaataaaGCTT GACAgagaaccccaatccCATTATTATAATAGAAATTGagtacatagcaaatgatgaa a" /listShort="NA, hisS, aspS, NA, yrvM" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-10 2683757..2683776 /Source="Nicolas_upshift_promotors" /id="U2126" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.582417582417582" /psig=1 /xcortree=2538 /SigmaFactorBS="ctgacctactcttctccattattggttcaaatctttcatcAT TTgctatgtactcaatTTCTATTATAATAATGGGATtggggttctctgtcaagcttta t" /listShort="S1044, yrvJ" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 2683759..2684043 /Source="Nicolas_S_feature" /locus_tag="new_2818161_2818445" /HighExp="H2O2, G135, G180, C30, G150, Paraq, Oxctl, dia15, LBGstat, LBGexp" /AntisenseName="yrzK" /AntisenseCor="-0.27832941694878799" /AntisenseRegPval="-5.4" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1044" upshifts 2683759 /Source="Nicolas_upshifts" /id="U2126" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.582417582417582" /psig=1 /xcortree=2538 /SigmaFactorBS="ctgacctactcttctccattattggttcaaatctttcatcAT TTgctatgtactcaatTTCTATTATAATAATGGGATtggggttctctgtcaagcttta t" /listShort="S1044, yrvJ" /GFF_Attribute="listLong" upshifts complement(2683772) /Source="Nicolas_upshifts" /id="U2127" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.9000999000999" /psig=1 /xcortree=3008 /SigmaFactorBS="ccaaagaagcagcgctgaggaaaaacaaccggaataaaGCTT GACAgagaaccccaatccCATTATTATAATAGAAATTGagtacatagcaaatgatgaa a" /listShort="NA, hisS, aspS, NA, yrvM" /GFF_Attribute="listLong" promotor_-35 complement(2683787..2683794) /Source="Nicolas_upshift_promotors" /id="U2127" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.9000999000999" /psig=1 /xcortree=3008 /SigmaFactorBS="ccaaagaagcagcgctgaggaaaaacaaccggaataaaGCTT GACAgagaaccccaatccCATTATTATAATAGAAATTGagtacatagcaaatgatgaa a" /listShort="NA, hisS, aspS, NA, yrvM" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2683789..2683959) /gene="yrzK" /locus_tag="BSU_27570" /old_locus_tag="BSU27570" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_390635.1" /db_xref="EnsemblGenomes-Gn:BSU27570" /db_xref="EnsemblGenomes-Tr:CAB14716" /db_xref="InterPro:IPR035378" /db_xref="SubtiList:BG13820" /db_xref="UniProtKB/Swiss-Prot:O32040" /translation="MKYHPKMGRAFHDGEANLHYSDHADPDTTGYLTETASEFGLMSK EAALRKNNRNKA*" gene complement(2683789..2683959) /gene="yrzK" /locus_tag="BSU_27570" /old_locus_tag="BSU27570" promotor_-10 complement(2683990..2684001) /Source="Nicolas_upshift_promotors" /id="U2128" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.945054945054945" /psig="0.945054945054945" /xcortree=906 /SigmaFactorBS="taaaaaagcattcttgtttaatatcgtaaagtcctttctgat tttTAAATAAaaataaaatgatttGTTTATACTAAGcgtaaatacaatcaaaaaggtg t" /listShort="yrzK, NA" /listLong="hisS, aspS, NA, yrvM" /label="promotor_-10" upshifts complement(2684007) /Source="Nicolas_upshifts" /id="U2128" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.945054945054945" /psig="0.945054945054945" /xcortree=906 /SigmaFactorBS="taaaaaagcattcttgtttaatatcgtaaagtcctttctgat tttTAAATAAaaataaaatgatttGTTTATACTAAGcgtaaatacaatcaaaaaggtg t" /listShort="yrzK, NA" /listLong="hisS, aspS, NA, yrvM" promotor_-35 complement(2684016..2684022) /Source="Nicolas_upshift_promotors" /id="U2128" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.945054945054945" /psig="0.945054945054945" /xcortree=906 /SigmaFactorBS="taaaaaagcattcttgtttaatatcgtaaagtcctttctgat tttTAAATAAaaataaaatgatttGTTTATACTAAGcgtaaatacaatcaaaaaggtg t" /listShort="yrzK, NA" /listLong="hisS, aspS, NA, yrvM" /label="promotor_-35" promotor_-35 2684019..2684026 /Source="Nicolas_upshift_promotors" /id="U2129" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2794 /SigmaFactorBS="ttacgcttagtataaacaaatcattttatttttaTTTAAAAA tcagaaaggacttTACGATATTAAACAAGAATgcttttttaatgatcatcagaaagga g" /listShort="yrvJ" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2684040..2684058 /Source="Nicolas_upshift_promotors" /id="U2129" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2794 /SigmaFactorBS="ttacgcttagtataaacaaatcattttatttttaTTTAAAAA tcagaaaggacttTACGATATTAAACAAGAATgcttttttaatgatcatcagaaagga g" /listShort="yrvJ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2684045 /Source="Nicolas_upshifts" /id="U2129" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2794 /SigmaFactorBS="ttacgcttagtataaacaaatcattttatttttaTTTAAAAA tcagaaaggacttTACGATATTAAACAAGAATgcttttttaatgatcatcagaaagga g" /listShort="yrvJ" /GFF_Attribute="listLong" CDS 2684092..2685648 /gene="yrvJ" /locus_tag="BSU_27580" /old_locus_tag="BSU27580" /EC_number="3.5.1.28" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative N-acetylmuramoyl-L-alanine amidase, family 3" /protein_id="NP_390636.1" /db_xref="EnsemblGenomes-Gn:BSU27580" /db_xref="EnsemblGenomes-Tr:CAB14717" /db_xref="GOA:O32041" /db_xref="InterPro:IPR002508" /db_xref="InterPro:IPR003646" /db_xref="InterPro:IPR017293" /db_xref="SubtiList:BG13806" /db_xref="UniProtKB/Swiss-Prot:O32041" /translation="MNKKYFVLIVCIIFTSALFPTFSSVTAAQGEAVIATDEMNVRSG PGLSYGITAEVKKGERYPILKEDGDWVQIQLGSGEKGWVVSWLITKEDQASTSSSGSS DTVTSTDPDLRMRSGPGTSYEVIGKFPQGSQASVIDKDSGWIKISYHSATGWVSSEYV TSGGSSSASDESDQTEDSGASTTGTVGVSSLNVRASASHDAAIITKLDRGTKLTVLNE KNGWAHIEVNGLKGWVASHYLLTSSVPADDSANAGSSSSAKKAYIMYGGTNLRSDAST SASIVERAAKGDSYTITGSKGSWYEIKLDNGQTAYVANWVVQTSKSAEEAGEPPVSDS PSGNGSLNNKTIIVDPGHGGKDSGTIGYSGKFEKNLTIKTAKLLASKLRSAGADVYVT RQDDTFVSLQSRVSTSHYRNADAFISIHYDSYADTSTRGSTAYYYSPAKDQELASDVH SEVVKRSSIPDRGVLFGDYYVLRENRQPAMLYELGYVSHPQEEAIVHSNSYQEKVTDG IESGLEKYFQ*" gene 2684092..2685648 /gene="yrvJ" /locus_tag="BSU_27580" /old_locus_tag="BSU27580" downshifts 2685627 /Source="Nicolas_upshifts" /id="D1412" /incds=0 /nref=199 /ntot=249 /MaxReadThrough="2.10072" /MaxDrop="7.40599" /score="44.9570925" /energy="-9.9" /TU="U2126" /idTUdmin="U2129" /TUdmin="-2" /isTUend="TRUE" CDS complement(2685675..2686073) /gene="dtd" /locus_tag="BSU_27590" /old_locus_tag="BSU27590" /EC_number="3.1.-.-" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 15292242, 15525705, 16844682, 18700836, 28362257; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="gly-tRNA(Ala) deacylase / D-Tyr-tRNATyr deacylase" /protein_id="NP_390637.2" /db_xref="EnsemblGenomes-Gn:BSU27590" /db_xref="EnsemblGenomes-Tr:CAB14718" /db_xref="GOA:O32042" /db_xref="InterPro:IPR003732" /db_xref="InterPro:IPR023509" /db_xref="SubtiList:BG13805" /db_xref="UniProtKB/Swiss-Prot:O32042" /translation="MDEEVVGQIGQGLMVLVGITHDDTEDDAAYLADKVVNLRIFDDS EGKMNLSLVDIGGEILSVSQFTLYGDTKKGRRPNYMNAAKPDKALGLYEKWNDLLREK GIKVETGTFGAMMDVQLTNSGPVTLIMDSK*" gene complement(2685675..2686073) /gene="dtd" /locus_tag="BSU_27590" /old_locus_tag="BSU27590" downshifts complement(2685683) /Source="Nicolas_upshifts" /id="D1413" /incds=0 /nref=152 /ntot=267 /MaxReadThrough="2.01735" /MaxDrop="9.47739" /score="37.3693259" /energy="-9.9" /TU="NA" /idTUdmin="U2130" /TUdmin=0 /isTUend="TRUE" CDS complement(2686127..2688331) /gene="rsh" /locus_tag="BSU_27600" /old_locus_tag="BSU27600" /EC_number="2.7.6.5" /EC_number="3.1.7.2" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:6248722, 9383190, 11545276, 12081964, 12372825, 13129942, 15066282, 17183219, 18067544, 18996989, 26460002" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 6248722, 9383190, 11545276, 12081964, 12372825, 13129942, 15066282, 17183219, 18067544, 18996989, 26460002; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="GTP pyrophosphokinase (RelA/SpoT)" /protein_id="NP_390638.2" /db_xref="EnsemblGenomes-Gn:BSU27600" /db_xref="EnsemblGenomes-Tr:CAB14719" /db_xref="GOA:O54408" /db_xref="InterPro:IPR002912" /db_xref="InterPro:IPR003607" /db_xref="InterPro:IPR004095" /db_xref="InterPro:IPR004811" /db_xref="InterPro:IPR007685" /db_xref="InterPro:IPR012675" /db_xref="InterPro:IPR012676" /db_xref="InterPro:IPR033655" /db_xref="SubtiList:BG12665" /db_xref="UniProtKB/Swiss-Prot:O54408" /translation="MANEQVLTAEQVIDKARSYLSDEHIAFVEKAYLYAEDAHREQYR KSGEPYIIHPIQVAGILVDLEMDPSTIAGGFLHDVVEDTDVTLDDLKEAFSEEVAMLV DGVTKLGKIKYKSQEEQQAENHRKMFVAMAQDIRVILIKLADRLHNMRTLKHLPQEKQ RRISNETLEIFAPLAHRLGISKIKWELEDTALRYLNPQQYYRIVNLMKKKRAERELYV DEVVNEVKKRVEEVNIKADFSGRPKHIYSIYRKMVLQNKQFNEIYDLLAVRILVNSIK DCYAVLGIIHTCWKPMPGRFKDYIAMPKPNMYQSLHTTVIGPKGDPLEVQIRTFEMHE IAEYGVAAHWAYKEGKAANEGATFEKKLSWFREILEFQNESTDAEEFMESLKIDLFSD MVYVFTPKGDVIELPSGSVPIDFSYRIHSEIGNKTIGAKVNGKMVTLDHKLRTGDIVE ILTSKHSYGPSQDWVKLAQTSQAKHKIRQFFKKQRREENVEKGRELVEKEIKNLDFEL KDVLTPENIQKVADKFNFSNEEDMYAAVGYNGITALQVANRLTEKERKQRDQEEQEKI VQEVTGEPKPYPQGRKREAGVRVKGIDNLLVRLSKCCNPVPGDDIVGFITKGRGVSVH REDCPNVKTNEAQERLIPVEWEHESQVQKRKEYNVEIEILGYDRRGLLNEVLQAVNET KTNISSVSGKSDRNKVATIHMAIFIQNINHLHKVVERIKQIRDIYSVRRVMN*" gene complement(2686127..2688331) /gene="rsh" /locus_tag="BSU_27600" /old_locus_tag="BSU27600" promotor_-10 complement(2688360..2688379) /Source="Nicolas_upshift_promotors" /id="U2130" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.648351648351648" /psig="0.998001998001998" /xcortree=2252 /SigmaFactorBS="taatatttggctatttgaacttctgcTCTTTACAtctttcgt ttttttCTTGATAATAAACTACAATAcagtttacattttaaaaaaggtgattccatgg c" /listShort="relA, dtd" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2688367) /Source="Nicolas_upshifts" /id="U2130" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.648351648351648" /psig="0.998001998001998" /xcortree=2252 /SigmaFactorBS="taatatttggctatttgaacttctgcTCTTTACAtctttcgt ttttttCTTGATAATAAACTACAATAcagtttacattttaaaaaaggtgattccatgg c" /listShort="relA, dtd" /GFF_Attribute="listLong" S_feature complement(2688369..2688459) /Source="Nicolas_S_feature" /locus_tag="new_2822771_2822861_c" /HighExp="Cold, G135, G180, G150, H2O2, Paraq, Oxctl, C30, LBGexp, BMM" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigK, SigA, SigB" /TUshortPSig="0.951, 1, 1" /TUlongSig="SigA, SigA" /TUlongPSig="0.999, 1" /label="S1045" promotor_-35 complement(2688394..2688401) /Source="Nicolas_upshift_promotors" /id="U2130" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.648351648351648" /psig="0.998001998001998" /xcortree=2252 /SigmaFactorBS="taatatttggctatttgaacttctgcTCTTTACAtctttcgt ttttttCTTGATAATAAACTACAATAcagtttacattttaaaaaaggtgattccatgg c" /listShort="relA, dtd" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 2688423 /Source="Nicolas_upshifts" /id="D1414" /incds=0 /nref=1 /ntot=14 /MaxReadThrough="1.75679" /MaxDrop="3.54336" /score="0.486890657" /energy="-12.7" /TU="NA" /idTUdmin="U2126" /TUdmin=2772 /isTUend="FALSE" CDS complement(2688499..2689011) /gene="apt" /locus_tag="BSU_27610" /old_locus_tag="BSU27610" /EC_number="2.4.2.7" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:6408059, 9383190, 15629952" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 6408059, 9383190, 15629952; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="adenine phosphoribosyltransferase" /protein_id="NP_390639.1" /db_xref="EnsemblGenomes-Gn:BSU27610" /db_xref="EnsemblGenomes-Tr:CAB14720" /db_xref="GOA:O34443" /db_xref="InterPro:IPR000836" /db_xref="InterPro:IPR005764" /db_xref="InterPro:IPR029057" /db_xref="SubtiList:BG12568" /db_xref="UniProtKB/Swiss-Prot:O34443" /translation="MDLKQYVTIVPDYPKEGVQFKDITTLMDKGDVYRYATDQIVEYA KEKQIDLVVGPEARGFIIGCPVAYALGVGFAPVRKEGKLPREVIKVDYGLEYGKDVLT IHKDAIKPGQRVLITDDLLATGGTIEATIKLVEELGGVVAGIAFLIELSYLDGRNKLE DYDILTLMKY*" gene complement(2688499..2689011) /gene="apt" /locus_tag="BSU_27610" /old_locus_tag="BSU27610" downshifts complement(2688504) /Source="Nicolas_upshifts" /id="D1415" /incds=0 /nref=39 /ntot=228 /MaxReadThrough="5.36411" /MaxDrop="4.05036" /score="2.83935873" /energy="-6.8" /TU="U2131,U2132,U2133" /idTUdmin="U2131" /TUdmin="-115" /isTUend="FALSE" CDS complement(2689017..2691377) /gene="recJ" /locus_tag="BSU_27620" /old_locus_tag="BSU27620" /EC_number="3.1.-.-" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:21087930, 21170359, 26001966" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 21087930, 21170359, 26001966; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="single-strand DNA-specific exonuclease" /protein_id="NP_390640.1" /db_xref="EnsemblGenomes-Gn:BSU27620" /db_xref="EnsemblGenomes-Tr:CAB14721" /db_xref="GOA:O32044" /db_xref="InterPro:IPR001667" /db_xref="InterPro:IPR003156" /db_xref="InterPro:IPR004610" /db_xref="InterPro:IPR018779" /db_xref="SubtiList:BG13804" /db_xref="UniProtKB/Swiss-Prot:O32044" /translation="MLASKMRWEIQRPDQDKVKSLTEQLHITPLVASLLVKRGFDTAE SARLFLHTKDADFYDPFEMKGMKEAADRIKQAISQQEKIMIYGDYDADGVTSTSVMLH TLQKLSAQVDFYIPDRFKEGYGPNEQAFRSIKERGFSLIITVDTGIAAVHEAKVAKEL GLDVIITDHHEPGPELPDVRAIVHPKQPGCTYPFKELAGVGVAFKLAHALLGELPDEL LDLAAIGTIADLVPLHDENRLIATLGLERLRRTNRLGLKELIKLSGGDIGEANEETVG FQLAPRLNAVGRIEQADPAVHLLMSEDSFEAEELAAEIDQLNKERQKMVSKMTDEAIE MVEQQGLDQTAIVVAKAGWNPGVVGIVASKLVDRFYRPAIVLGIDEEKGIAKGSARSI RGFNLFESLSECRDILPHFGGHPMAAGMTLKAEDVPDLRSRLNEIADNTLTEEDFIPV QEVDLVCGVEDITVESIAEMNMLSPFGMLNPKPHVLVENAVLEDVRKIGANKTHVKMT IRNESSQLDCVGFNKGELQEGIVPGSRISIVGEMSINEWNNRKKPQLMIKDAAVSEWQ LFDLRGKRTWEDTVSALPSAKRAIVSFKEDSTTLLQTEDLRREVHVISSKDQAKAFDL DGAYIVLLDPPPSLDMLARLLEGKAPERIYFIFLNHEDHFLSTFPARDHFKWYYAFLL KRGAFDVKKHGSELAKHKGWSVETINFMTKVFFDLGFVKIENGVLSVVSGAKKRDLTD SQTYQAKQQLMELDQKLNYSSAEELKEWLNKLMKQDSEAYESTRRT*" gene complement(2689017..2691377) /gene="recJ" /locus_tag="BSU_27620" /old_locus_tag="BSU27620" promotor_-10 complement(2689481..2689500) /Source="Nicolas_upshift_promotors" /id="U2131" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.95104895104895" /psig="0.95104895104895" /xcortree=754 /SigmaFactorBS="tgcacgtcatcagttctaaagatcaaGCAAAGGCGTttgacc tcgatggTGCATATATTGTATTACTGGatccgccgccttcgctggacatgctcgcacg t" /listShort="apt, S1045" /listLong="relA, dtd" /label="promotor_-10" upshifts complement(2689489) /Source="Nicolas_upshifts" /id="U2131" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.95104895104895" /psig="0.95104895104895" /xcortree=754 /SigmaFactorBS="tgcacgtcatcagttctaaagatcaaGCAAAGGCGTttgacc tcgatggTGCATATATTGTATTACTGGatccgccgccttcgctggacatgctcgcacg t" /listShort="apt, S1045" /listLong="relA, dtd" promotor_-35 complement(2689514..2689523) /Source="Nicolas_upshift_promotors" /id="U2131" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.95104895104895" /psig="0.95104895104895" /xcortree=754 /SigmaFactorBS="tgcacgtcatcagttctaaagatcaaGCAAAGGCGTttgacc tcgatggTGCATATATTGTATTACTGGatccgccgccttcgctggacatgctcgcacg t" /listShort="apt, S1045" /listLong="relA, dtd" /label="promotor_-35" promotor_-10 complement(2691391..2691410) /Source="Nicolas_upshift_promotors" /id="U2132" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.493506493506494" /psig=1 /xcortree=2600 /SigmaFactorBS="gattgagaaaaaagactagttttcgaatattATTTGAAaccc ctcagcctgcTCTAGTATAATAGGGTGGTTgaggggtgaatttatgttagcgtcaaaa a" /listShort="recJ, apt, S1045, relA, dtd" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2691402) /Source="Nicolas_upshifts" /id="U2132" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.493506493506494" /psig=1 /xcortree=2600 /SigmaFactorBS="gattgagaaaaaagactagttttcgaatattATTTGAAaccc ctcagcctgcTCTAGTATAATAGGGTGGTTgaggggtgaatttatgttagcgtcaaaa a" /listShort="recJ, apt, S1045, relA, dtd" /GFF_Attribute="listLong" promotor_-35 complement(2691425..2691431) /Source="Nicolas_upshift_promotors" /id="U2132" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.493506493506494" /psig=1 /xcortree=2600 /SigmaFactorBS="gattgagaaaaaagactagttttcgaatattATTTGAAaccc ctcagcctgcTCTAGTATAATAGGGTGGTTgaggggtgaatttatgttagcgtcaaaa a" /listShort="recJ, apt, S1045, relA, dtd" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2691444..2691767) /gene="yrvD" /locus_tag="BSU_27630" /old_locus_tag="BSU27630" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_390641.1" /db_xref="EnsemblGenomes-Gn:BSU27630" /db_xref="EnsemblGenomes-Tr:CAB14722" /db_xref="GOA:O32045" /db_xref="InterPro:IPR010445" /db_xref="SubtiList:BG13803" /db_xref="UniProtKB/Swiss-Prot:O32045" /translation="MNKQWTIIFALIFTLIVAIFAVINVRSVEVDYLFGRSEWPLILV ILGSVLMGALIVFSVGIFQVMKLKREIKTLRKENRTAIHKQEDTHLADQTDTQDASAM IEKKD*" gene complement(2691444..2691767) /gene="yrvD" /locus_tag="BSU_27630" /old_locus_tag="BSU27630" promotor_-10 complement(2691788..2691806) /Source="Nicolas_upshift_promotors" /id="U2133" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=175 /SigmaFactorBS="cagcaaagggagcttaacctagtgttaagccaTGTTTAAaac cagtcttgattGGGAAAGTTACCTCAATAAgaagtttgggggaaaagagaatgaataa a" /listShort="yrvD, recJ, apt, S1045" /listLong="relA, dtd" /label="promotor_-10" upshifts complement(2691799) /Source="Nicolas_upshifts" /id="U2133" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=175 /SigmaFactorBS="cagcaaagggagcttaacctagtgttaagccaTGTTTAAaac cagtcttgattGGGAAAGTTACCTCAATAAgaagtttgggggaaaagagaatgaataa a" /listShort="yrvD, recJ, apt, S1045" /listLong="relA, dtd" promotor_-35 complement(2691821..2691827) /Source="Nicolas_upshift_promotors" /id="U2133" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=175 /SigmaFactorBS="cagcaaagggagcttaacctagtgttaagccaTGTTTAAaac cagtcttgattGGGAAAGTTACCTCAATAAgaagtttgggggaaaagagaatgaataa a" /listShort="yrvD, recJ, apt, S1045" /listLong="relA, dtd" /label="promotor_-35" CDS complement(2691843..2692340) /gene="yrvC" /locus_tag="BSU_27640" /old_locus_tag="BSU27640" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 14563871; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative potassium transport accessory component" /protein_id="NP_390642.1" /db_xref="EnsemblGenomes-Gn:BSU27640" /db_xref="EnsemblGenomes-Tr:CAB14723" /db_xref="GOA:O32046" /db_xref="InterPro:IPR006037" /db_xref="InterPro:IPR026278" /db_xref="InterPro:IPR036721" /db_xref="SubtiList:BG13802" /db_xref="UniProtKB/Swiss-Prot:O32046" /translation="MRVRESELPGIGQKVEMITRNRDKISIIIHHDGRRELYYFDEND HEECVASVQFDDAEARQMSAILGGMAYKPKALEQVESALDDLIIEWCKAEAGAPAIHQ TIGDLNVGQEYHVTVIAIVKKNQDKQLNPSSETVIDEGDTLVISGEGTGLKRLIREKL TAKGA*" gene complement(2691843..2692340) /gene="yrvC" /locus_tag="BSU_27640" /old_locus_tag="BSU27640" S_feature complement(2692341..2692416) /Source="Nicolas_S_feature" /locus_tag="new_2826743_2826818_c" /HighExp="Oxctl, HiOs, G180, LBGexp, Paraq, G150, G135, H2O2, MG-0.2, Mal" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="0.999, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S1046" promotor_-10 complement(2692410..2692429) /Source="Nicolas_upshift_promotors" /id="U2134" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.485514485514486" /psig="0.999000999001" /xcortree=2308 /SigmaFactorBS="cagggcagcctgttttttgaagtttcATTGAACTtaaaatag acattTGCTATAATGACATACGCTTacatttaaacatatatatggtgttaaaagtgtt t" /listShort="S1046, yrvC, yrvD, recJ" /listLong="apt, S1045, relA, dtd" /label="promotor_-10" upshifts complement(2692416) /Source="Nicolas_upshifts" /id="U2134" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.485514485514486" /psig="0.999000999001" /xcortree=2308 /SigmaFactorBS="cagggcagcctgttttttgaagtttcATTGAACTtaaaatag acattTGCTATAATGACATACGCTTacatttaaacatatatatggtgttaaaagtgtt t" /listShort="S1046, yrvC, yrvD, recJ" /listLong="apt, S1045, relA, dtd" promotor_-35 complement(2692443..2692450) /Source="Nicolas_upshift_promotors" /id="U2134" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.485514485514486" /psig="0.999000999001" /xcortree=2308 /SigmaFactorBS="cagggcagcctgttttttgaagtttcATTGAACTtaaaatag acattTGCTATAATGACATACGCTTacatttaaacatatatatggtgttaaaagtgtt t" /listShort="S1046, yrvC, yrvD, recJ" /listLong="apt, S1045, relA, dtd" /label="promotor_-35" CDS complement(2692498..2694711) /gene="secDF" /locus_tag="BSU_27650" /old_locus_tag="BSU27650" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:9694879, 15941986, 15995216, 16517687" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9694879, 15941986, 15995216, 16517687; Product type t: transporter" /codon_start=1 /transl_table=11 /product="protein-export membrane protein" /protein_id="NP_390643.1" /db_xref="EnsemblGenomes-Gn:BSU27650" /db_xref="EnsemblGenomes-Tr:CAB14724" /db_xref="GOA:O32047" /db_xref="InterPro:IPR005665" /db_xref="InterPro:IPR005791" /db_xref="InterPro:IPR022645" /db_xref="InterPro:IPR022646" /db_xref="InterPro:IPR022813" /db_xref="SubtiList:BG12672" /db_xref="UniProtKB/Swiss-Prot:O32047" /translation="MKKGRLIAFFLFVLLIGTGLGYFTKPAANNITLGLDLQGGFEVL YDVQPVKKGDKITKDVLVSTVEALNRRANVLGVSEPNIQIEGNNRIRVQLAGVTNQNR AREILATEAQLSFRDANDKELLNGADLVENGAKQTYDSTTNEPIVTIKLKDADKFGEV TKKVMKMAPNNQLVIWLDYDKGDSFKKEVQKEHPKFVSAPNVSQELNTTDVKIEGHFT AQEAKDLASILNAGALPVKLTEKYSTSVGAQFGQQALHDTVFAGIVGIAIIFLFMLFY YRLPGLIAVITLSVYIYITLQIFDWMNAVLTLPGIAALILGVGMAVDANIITYERIKE ELKLGKSVRSAFRSGNRRSFATIFDANITTIIAAVVLFIFGTSSVKGFATMLILSILT SFITAVFLSRFLLALLVESRWLDRKKGWFGVNKKHIMDIQDTDENTEPHTPFQKWDFT SKRKYFFIFSSAVTVAGIIILLVFRLNLGIDFASGARIEVQSDHKLTTEQVEKDFESL GMDPDTVVLSGEKSNIGVARFVGVPDKETIAKVKTYFKDKYGSDPNVSTVSPTVGKEL ARNALYAVAIASIGIIIYVSIRFEYKMAIAAIASLLYDAFFIVTFFSITRLEVDVTFI AAILTIIGYSINDTIVTFDRVREHMKKRKPKTFADLNHIVNLSLQQTFTRSINTVLTV VIVVVTLLIFGASSITNFSIALLVGLLTGVYSSLYIAAQIWLAWKGRELKKDSAQ*" gene complement(2692498..2694711) /gene="secDF" /locus_tag="BSU_27650" /old_locus_tag="BSU27650" downshifts complement(2692503) /Source="Nicolas_upshifts" /id="D1416" /incds=0 /nref=174 /ntot=249 /MaxReadThrough="4.49738" /MaxDrop="5.0013" /score="29.1843057" /energy="-17.8" /TU="U2137" /idTUdmin="U2137" /TUdmin="-1100" /isTUend="FALSE" promotor_-35 2694270..2694275 /Source="Nicolas_upshift_promotors" /id="U2135" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.625374625374625" /psig="0.987012987012987" /xcortree=604 /SigmaFactorBS="caccaaatttatcagcgtctttcagcttaatcgTGACAAttg gctcatttgtTGTGCTATCATAAGTTTGTTtagcgccgttttcgactagatcagcacc g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2694289..2694308 /Source="Nicolas_upshift_promotors" /id="U2135" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.625374625374625" /psig="0.987012987012987" /xcortree=604 /SigmaFactorBS="caccaaatttatcagcgtctttcagcttaatcgTGACAAttg gctcatttgtTGTGCTATCATAAGTTTGTTtagcgccgttttcgactagatcagcacc g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2694297 /Source="Nicolas_upshifts" /id="U2135" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.625374625374625" /psig="0.987012987012987" /xcortree=604 /SigmaFactorBS="caccaaatttatcagcgtctttcagcttaatcgTGACAAttg gctcatttgtTGTGCTATCATAAGTTTGTTtagcgccgttttcgactagatcagcacc g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" CDS complement(2694750..2695046) /gene="comN" /locus_tag="BSU_27660" /old_locus_tag="BSU27660" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:19028902, 27059541" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 19028902, 27059541; Product type r: regulator" /codon_start=1 /transl_table=11 /product="post-transcriptional regulator" /protein_id="NP_390644.1" /db_xref="EnsemblGenomes-Gn:BSU27660" /db_xref="EnsemblGenomes-Tr:CAB14726" /db_xref="GOA:O32049" /db_xref="InterPro:IPR025716" /db_xref="SubtiList:BG13814" /db_xref="UniProtKB/Swiss-Prot:O32049" /translation="MEKHPADLYKDHVRPFLYSKLEEFKILGYDDVELESLWSYLTDK KWKKKTELSIYELASDILSVKIGEFMNYATVESFKTSNWLGSEEGQEALEELLR*" gene complement(2694750..2695046) /gene="comN" /locus_tag="BSU_27660" /old_locus_tag="BSU27660" downshifts 2694957 /Source="Nicolas_upshifts" /id="D1417" /incds=1 /nref=1 /ntot=66 /MaxReadThrough="1.36122" /MaxDrop="2.33158" /score="-9.07145122" /energy="-8.4" /TU="NA" /idTUdmin="U2136" /TUdmin="-2508" /isTUend="FALSE" S_feature complement(2695047..2695125) /Source="Nicolas_S_feature" /locus_tag="new_2829449_2829527_c" /HighExp="LBGtran, Lbtran, C90, M40t45, HiOs, Lbexp, Cold, M0t45, UNK1, M0t90" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="SigH" /TUlongPSig=1 /label="S1047" promotor_-35 2695087..2695092 /Source="Nicolas_upshift_promotors" /id="U2136" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=986 /SigmaFactorBS="tccacgctccttttttattgtttttcaagaagacttGTCATG cttggacgacatatacGCATATCTTTATTGTATATgattccaggtagtttgagaaggc a" /listShort="spoVB, S1049" /listLong="yrzE" /label="promotor_-35" promotor_-10 2695109..2695127 /Source="Nicolas_upshift_promotors" /id="U2136" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=986 /SigmaFactorBS="tccacgctccttttttattgtttttcaagaagacttGTCATG cttggacgacatatacGCATATCTTTATTGTATATgattccaggtagtttgagaaggc a" /listShort="spoVB, S1049" /listLong="yrzE" /label="promotor_-10" promotor_-10 complement(2695111..2695130) /Source="Nicolas_upshift_promotors" /id="U2137" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.787212787212787" /psig=1 /xcortree=2330 /SigmaFactorBS="ctttaaaaacgtctgtttcgccatttttaccccctgcCTTCt caaactacctggaATCATATACAATAAAGATATgcgtatatgtcgtccaagcatgaca a" /listShort="S1047, comN, secDF, S1046, yrvC, yrvD" /listLong="recJ, apt, S1045, relA, dtd" /label="promotor_-10" upshifts 2695111 /Source="Nicolas_upshifts" /id="U2136" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=986 /SigmaFactorBS="tccacgctccttttttattgtttttcaagaagacttGTCATG cttggacgacatatacGCATATCTTTATTGTATATgattccaggtagtttgagaaggc a" /listShort="spoVB, S1049" /listLong="yrzE" upshifts complement(2695125) /Source="Nicolas_upshifts" /id="U2137" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.787212787212787" /psig=1 /xcortree=2330 /SigmaFactorBS="ctttaaaaacgtctgtttcgccatttttaccccctgcCTTCt caaactacctggaATCATATACAATAAAGATATgcgtatatgtcgtccaagcatgaca a" /listShort="S1047, comN, secDF, S1046, yrvC, yrvD" /listLong="recJ, apt, S1045, relA, dtd" S_feature complement(2695127..2696045) /Source="Nicolas_S_feature" /locus_tag="new_2829529_2830447_c" /HighExp="S2, M9-stat, Lbstat, BC, T2.0H, T3.0H, T2.30H, T3.30H, Cold, M0t90" /AntisenseName="spoVB" /AntisenseCor="-8.5173616652496897E-2" /AntisenseRegPval="-0.8" /CDS_PredictionProba="NA" /TUshortSig="SigH" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1048" promotor_-35 complement(2695145..2695148) /Source="Nicolas_upshift_promotors" /id="U2137" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.787212787212787" /psig=1 /xcortree=2330 /SigmaFactorBS="ctttaaaaacgtctgtttcgccatttttaccccctgcCTTCt caaactacctggaATCATATACAATAAAGATATgcgtatatgtcgtccaagcatgaca a" /listShort="S1047, comN, secDF, S1046, yrvC, yrvD" /listLong="recJ, apt, S1045, relA, dtd" /label="promotor_-35" CDS 2695162..2696718 /gene="spoVB" /locus_tag="BSU_27670" /old_locus_tag="BSU27670" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:1744050, 15292147, 15849754, 16850406, 17714441, 19648239" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1744050, 15292147, 15849754, 16850406, 17714441, 19648239; Product type t : transporter" /codon_start=1 /transl_table=11 /product="involved in spore cortex synthesis (stage V sporulation); translocase with flippase function for peptidoglycan synthesis" /protein_id="NP_390645.1" /db_xref="EnsemblGenomes-Gn:BSU27670" /db_xref="EnsemblGenomes-Tr:CAB14727" /db_xref="GOA:Q00758" /db_xref="InterPro:IPR002797" /db_xref="InterPro:IPR014249" /db_xref="InterPro:IPR024923" /db_xref="InterPro:IPR029303" /db_xref="SubtiList:BG10778" /db_xref="UniProtKB/Swiss-Prot:Q00758" /translation="MAKQTFLKGTLILIAAGMVTRMLGFVNRVVIARFIGEEGVGLYM MAAPTFFLATTLTQFGLPVAISKLVAEASARGDHQKTKNILVMSLTITGVLSLIFTPL FLFFAPVMAETMLTDKRTLYPLLAITPVVPIIAISSVLRGYFQGKQNMNPLAMSQVLE QVVRISLVAVCTTIFLPYGIEYAAAGAMLSSVAGELASLLYLFVCFKYKKTIKIRKHF LQSIKNGKQTFTQLMSVSLPTTGSRFIGNLSWFFEPIVVAQSLAIAGVATVAATKQYG ELTGFAMTLLTLPSFITYSLSTALVPAISEGMEQKKLQVVEYRLEQAMRLCLLSGGIS VVILFVFADELMRVMYGSSGAAVFIKVMAPFFLLYYFQGPLQAVLQALNLAGAAMMNS LIGALVKTGLIFVLATRPSLGIMGAALAIVTGMVLVTLLHAATVSKVLPISIKIKEYA LSFAVIVICGFISSAIKQYISFGASEAVNLAGWIAASAAIYMILLLVFRLIKKDELRR IPIIGRLIIR*" gene 2695162..2696718 /gene="spoVB" /locus_tag="BSU_27670" /old_locus_tag="BSU27670" promotor_-10 complement(2696031..2696049) /Source="Nicolas_upshift_promotors" /id="U2138" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp=1 /psig=1 /xcortree=549 /SigmaFactorBS="acctgcaattttttctgctccattccttcactgatcGCAGGA ACAagcgcggtcgaCAAAGAATATGTAATAAAGctgggcagagtcagcagcgtcatgg c" /listShort="S1048" /listLong="S1047, comN, secDF" /label="promotor_-10" upshifts complement(2696045) /Source="Nicolas_upshifts" /id="U2138" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp=1 /psig=1 /xcortree=549 /SigmaFactorBS="acctgcaattttttctgctccattccttcactgatcGCAGGA ACAagcgcggtcgaCAAAGAATATGTAATAAAGctgggcagagtcagcagcgtcatgg c" /listShort="S1048" /listLong="S1047, comN, secDF" promotor_-35 complement(2696061..2696069) /Source="Nicolas_upshift_promotors" /id="U2138" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp=1 /psig=1 /xcortree=549 /SigmaFactorBS="acctgcaattttttctgctccattccttcactgatcGCAGGA ACAagcgcggtcgaCAAAGAATATGTAATAAAGctgggcagagtcagcagcgtcatgg c" /listShort="S1048" /listLong="S1047, comN, secDF" /label="promotor_-35" S_feature 2696719..2697483 /Source="Nicolas_S_feature" /locus_tag="new_2831121_2831885" /HighExp="S3, BT, S4, LoTm, S7, S8, T5.0H, T4.0H, M9-stat, T3.30H" /AntisenseName="yrbG" /AntisenseCor="0.65629957843767395" /AntisenseRegPval="-33.799999999999997" /CDS_PredictionProba="NA" /TUshortSig="SigEF" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1049" CDS complement(2696722..2697378) /gene="yrbG" /locus_tag="BSU_27680" /old_locus_tag="BSU27680" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_390646.1" /db_xref="EnsemblGenomes-Gn:BSU27680" /db_xref="EnsemblGenomes-Tr:CAB14728" /db_xref="GOA:O32050" /db_xref="InterPro:IPR007353" /db_xref="InterPro:IPR023090" /db_xref="SubtiList:BG13786" /db_xref="UniProtKB/Swiss-Prot:O32050" /translation="MEELLTIAFRTVVLYFVILVIFRFMGKREIGELSILDLVVFIMM AEIAVLAIENVDDHLFHTILPMLVLMIIQVTLAYFSLKNRKVRQLLDGKPTIIIKYGK IDEEAMKSQRYNFDDLMVQLRENSIDRVADVSFAILEPSGKLTIVKKENSGEHRQLEM PLIIDGFIQTENLSRISKDRKWLLESLQKHGYTNPSDISFCSFTDGEIYIDEKDGHRT *" gene complement(2696722..2697378) /gene="yrbG" /locus_tag="BSU_27680" /old_locus_tag="BSU27680" promotor_-10 complement(2697397..2697408) /Source="Nicolas_upshift_promotors" /id="U2139" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=940 /SigmaFactorBS="aattagacgtaaaagctttgtgaaatgcaatcggtttttctT ACATAAattgatcattttgTTGCAACCTATAatgagttggaggtgcataatggaagag c" /listShort="yrbG" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2697409) /Source="Nicolas_upshifts" /id="U2139" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=940 /SigmaFactorBS="aattagacgtaaaagctttgtgaaatgcaatcggtttttctT ACATAAattgatcattttgTTGCAACCTATAatgagttggaggtgcataatggaagag c" /listShort="yrbG" /GFF_Attribute="listLong" promotor_-35 complement(2697422..2697428) /Source="Nicolas_upshift_promotors" /id="U2139" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=940 /SigmaFactorBS="aattagacgtaaaagctttgtgaaatgcaatcggtttttctT ACATAAattgatcattttgTTGCAACCTATAatgagttggaggtgcataatggaagag c" /listShort="yrbG" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 2697461..2697466 /Source="Nicolas_upshift_promotors" /id="U2140" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=977 /SigmaFactorBS="tgtaagaaaaaccgattgcatttcacaaagcttttaCGTCTA attcatgggataaggGAATACATTTTTACAAAGAcgagccatcagcatgtctgacggt t" /listShort="yrzE" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2697482..2697500 /Source="Nicolas_upshift_promotors" /id="U2140" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=977 /SigmaFactorBS="tgtaagaaaaaccgattgcatttcacaaagcttttaCGTCTA attcatgggataaggGAATACATTTTTACAAAGAcgagccatcagcatgtctgacggt t" /listShort="yrzE" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2697485 /Source="Nicolas_upshifts" /id="U2140" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=977 /SigmaFactorBS="tgtaagaaaaaccgattgcatttcacaaagcttttaCGTCTA attcatgggataaggGAATACATTTTTACAAAGAcgagccatcagcatgtctgacggt t" /listShort="yrzE" /GFF_Attribute="listLong" CDS 2697513..2697965 /gene="yrzE" /locus_tag="BSU_27690" /old_locus_tag="BSU27690" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative transporter" /protein_id="NP_390647.1" /db_xref="EnsemblGenomes-Gn:BSU27690" /db_xref="EnsemblGenomes-Tr:CAB14729" /db_xref="GOA:O32051" /db_xref="InterPro:IPR023804" /db_xref="SubtiList:BG13815" /db_xref="UniProtKB/Swiss-Prot:O32051" /translation="MSDGFEQKEQKPFNTGREETIMEETKQVGKGILYGLIAIFSAML LTSLAVSLLLTATSLEESSFNWLITAISFLSLFIGGFISGGKGKERGWMIGALTALSF SLIILLFQYLGFGKTFTAEQLIFHLGFLGVCMLGGIFGVNMRGNRSST*" gene 2697513..2697965 /gene="yrzE" /locus_tag="BSU_27690" /old_locus_tag="BSU27690" downshifts 2697949 /Source="Nicolas_upshifts" /id="D1418" /incds=0 /nref=39 /ntot=61 /MaxReadThrough="1.45569" /MaxDrop="7.7199" /score="41.7975947" /energy="-15" /TU="NA" /idTUdmin="U2140" /TUdmin=0 /isTUend="TRUE" downshifts complement(2698004) /Source="Nicolas_upshifts" /id="D1419" /incds=0 /nref=188 /ntot=281 /MaxReadThrough="2.20451" /MaxDrop="7.91954" /score="33.5938356" /energy="-15" /TU="NA" /idTUdmin="U2141" /TUdmin="-1" /isTUend="TRUE" CDS complement(2698022..2698288) /gene="yrbF" /locus_tag="BSU_27700" /old_locus_tag="BSU27700" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 10974125, 16166550, 21235483, 26790414; Product type t: transporter" /codon_start=1 /transl_table=11 /product="component of the preprotein translocase" /protein_id="NP_390648.2" /db_xref="EnsemblGenomes-Gn:BSU27700" /db_xref="EnsemblGenomes-Tr:CAB14730" /db_xref="GOA:O32052" /db_xref="InterPro:IPR003849" /db_xref="SubtiList:BG13785" /db_xref="UniProtKB/Swiss-Prot:O32052" /translation="MTGTLGTLVPIILMFAVLYFLLIRPQQKQQKAVRQMQEELKKGD SVVTIGGLHGTVDSIDESKVVIKTGDNTRLTFDRRAIREVSAAE*" gene complement(2698022..2698288) /gene="yrbF" /locus_tag="BSU_27700" /old_locus_tag="BSU27700" CDS complement(2698325..2699470) /gene="tgt" /locus_tag="BSU_27710" /old_locus_tag="BSU27710" /EC_number="2.4.2.29" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 12123838, 14660578, 16199558, 16206323; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="tRNA-guanine transglycosylase" /protein_id="NP_390649.1" /db_xref="EnsemblGenomes-Gn:BSU27710" /db_xref="EnsemblGenomes-Tr:CAB14731" /db_xref="GOA:O32053" /db_xref="InterPro:IPR002616" /db_xref="InterPro:IPR004803" /db_xref="InterPro:IPR036511" /db_xref="SubtiList:BG12686" /db_xref="UniProtKB/Swiss-Prot:O32053" /translation="MAEQPIRYEFIKECKQTGARLGKVHTPHGSFETPVFMPVGTLAT VKTMSPEELKAMDAGIILSNTYHLWLRPGQDIVKEAGGLHKFMNWDRAILTDSGGFQV FSLSKFRNIEEEGVHFRNHLNGDKLFLSPEKAMEIQNALGSDIMMAFDECPPYPAEYD YMKRSVERTSRWAERCLNAHNRQDEQGLFGIVQGGEYEDLRTQSAKDLISLDFPGYAI GGLSVGEPKDVMNRVLEFTTPLLPKDKPRYLMGVGSPDALIDGAIRGVDMFDCVLPTR IARNGTVFTAEGRLNMKNAKFERDFRPIDEECDCYTCKNYTRAYIRHLIRCNETFGLR LTTYHNLHFLLHLMEQVRQAIREDRLGDFREEFFERYGYNKPNAKSF*" gene complement(2698325..2699470) /gene="tgt" /locus_tag="BSU_27710" /old_locus_tag="BSU27710" upshifts complement(2698377) /Source="Nicolas_upshifts" /id="U2141" /multdbtbs="-" /comp="M20" /sig="Sig-" /pcomp="0.432567432567433" /psig="0.164835164835165" /xcortree=2327 /SigmaFactorBS="tacacttaatggagcaggtaagacaggctattcgcgaggatc gtctgggtgatttcaGagaagagttctttgagcgttacggctataacaagccaaatgc g" /listShort="yrbF" /GFF_Attribute="listLong" misc_feature complement(2698380) /Source="Nicolas_upshift_promotors" /id="U2141" /multdbtbs="-" /comp="M20" /sig="Sig-" /pcomp="0.432567432567433" /psig="0.164835164835165" /xcortree=2327 /SigmaFactorBS="tacacttaatggagcaggtaagacaggctattcgcgaggatc gtctgggtgatttcaGagaagagttctttgagcgttacggctataacaagccaaatgc g" /listShort="yrbF" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(2698421) /Source="Nicolas_upshifts" /id="U2142" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.380619380619381" /psig="0.98901098901099" /xcortree=2457 /SigmaFactorBS="attcggccttcgattaacaACTTACcataaccttcatttTCT GTTACACTTAATGGAGCaggtaagacaggctattcgcgaggatcgtctgggtgatttc a" /listShort="yrbF" /GFF_Attribute="listLong" promotor_-10 complement(2698423..2698442) /Source="Nicolas_upshift_promotors" /id="U2142" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.380619380619381" /psig="0.98901098901099" /xcortree=2457 /SigmaFactorBS="attcggccttcgattaacaACTTACcataaccttcatttTCT GTTACACTTAATGGAGCaggtaagacaggctattcgcgaggatcgtctgggtgatttc a" /listShort="yrbF" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 complement(2698457..2698462) /Source="Nicolas_upshift_promotors" /id="U2142" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.380619380619381" /psig="0.98901098901099" /xcortree=2457 /SigmaFactorBS="attcggccttcgattaacaACTTACcataaccttcatttTCT GTTACACTTAATGGAGCaggtaagacaggctattcgcgaggatcgtctgggtgatttc a" /listShort="yrbF" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2699497..2700525) /gene="queA" /locus_tag="BSU_27720" /old_locus_tag="BSU27720" /EC_number="2.4.99.17" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:10939241, 15822125, 17083917, 10739928" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10939241, 15822125, 17083917, 10739928; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="S-adenosylmethionine tRNA ribosyltransferase-isomerase" /protein_id="NP_390650.1" /db_xref="EnsemblGenomes-Gn:BSU27720" /db_xref="EnsemblGenomes-Tr:CAB14732" /db_xref="GOA:O32054" /db_xref="InterPro:IPR003699" /db_xref="InterPro:IPR036100" /db_xref="PDB:1YY3" /db_xref="SubtiList:BG12662" /db_xref="UniProtKB/Swiss-Prot:O32054" /translation="MKVDLFDFELPERLIAQVPLEQRDASRLMVLDKHTGELTDSSFK HIISFFNEGDCLVLNNTRVLPARLFGTKEDTGAKVELLLLKQETGDKWETLAKPAKRV KKGTVVTFGDGRLKAICTEELEHGGRKMEFQYDGIFYEVLESLGEMPLPPYIKEQLDD KERYQTVYSKEIGSAAAPTAGLHFTEEILQQLKDKGVQIEFITLHVGLGTFRPVSADE VEEHNMHAEFYQMSEETAAALNKVRENGGRIISVGTTSTRTLETIAGEHDGQFKASSG WTSIFIYPGYEFKAIDGMITNFHLPKSSLIMLVSALAGRENILRAYNHAVEEEYRFFS FGDAMLII*" gene complement(2699497..2700525) /gene="queA" /locus_tag="BSU_27720" /old_locus_tag="BSU27720" CDS complement(2700555..2700755) /gene="yrzS" /locus_tag="BSU_27729" /old_locus_tag="BSU27729" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="conserved membrane protein of unknown function" /protein_id="YP_003097768.1" /db_xref="EnsemblGenomes-Gn:BSU27729" /db_xref="EnsemblGenomes-Tr:CAX52674" /db_xref="GOA:C0H463" /db_xref="InterPro:IPR021320" /db_xref="UniProtKB/Swiss-Prot:C0H463" /translation="MTEFPKIIMILGAVLLIIGAVLHFVGKMPGDIFVKKGNVTFFFP VVTCIIISVVLSILLNLFGRMK*" gene complement(2700555..2700755) /gene="yrzS" /locus_tag="BSU_27729" /old_locus_tag="BSU27729" CDS complement(2700748..2701752) /gene="ruvB" /locus_tag="BSU_27730" /old_locus_tag="BSU27730" /EC_number="3.1.22.4" /function="16.6: Maintain" /function="16.9: Replicate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 14701911, 15317759, 16267290, 19422832, 21600217, 24770420; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="Holliday junction DNA helicase, ATP-dependent component" /protein_id="YP_054590.1" /db_xref="EnsemblGenomes-Gn:BSU27730" /db_xref="EnsemblGenomes-Tr:CAB14733" /db_xref="GOA:O32055" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR004605" /db_xref="InterPro:IPR008823" /db_xref="InterPro:IPR008824" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG12669" /db_xref="UniProtKB/Swiss-Prot:O32055" /translation="MDERLVSSEADNHESVIEQSLRPQNLAQYIGQHKVKENLRVFID AAKMRQETLDHVLLYGPPGLGKTTLASIVANEMGVELRTTSGPAIERPGDLAAILTAL EPGDVLFIDEIHRLHRSIEEVLYPAMEDFCLDIVIGKGPSARSVRLDLPPFTLVGATT RVGLLTAPLRDRFGVMSRLEYYTQEELADIVTRTADVFEVEIDKPSALEIARRSRGTP RVANRLLRRVRDFAQVLGDSRITEDISQNALERLQVDRLGLDHIDHKLLMGMIEKFNG GPVGLDTISATIGEESHTIEDVYEPYLLQIGFIQRTPRGRIVTPAVYHHFQMEAPRYD *" gene complement(2700748..2701752) /gene="ruvB" /locus_tag="BSU_27730" /old_locus_tag="BSU27730" CDS complement(2701763..2702368) /gene="ruvA" /locus_tag="BSU_27740" /old_locus_tag="BSU27740" /EC_number="3.1.22.4" /function="16.9: Replicate" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:14701911, 15317759, 16267290, 24770420" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 14701911, 15317759, 16267290, 24770420; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="Holliday junction DNA helicase" /protein_id="NP_390652.1" /db_xref="EnsemblGenomes-Gn:BSU27740" /db_xref="EnsemblGenomes-Tr:CAB14734" /db_xref="GOA:O05392" /db_xref="InterPro:IPR000085" /db_xref="InterPro:IPR003583" /db_xref="InterPro:IPR010994" /db_xref="InterPro:IPR011114" /db_xref="InterPro:IPR012340" /db_xref="InterPro:IPR013849" /db_xref="InterPro:IPR036267" /db_xref="SubtiList:BG11973" /db_xref="UniProtKB/Swiss-Prot:O05392" /translation="MIEFVKGTIDYVSPQYIVIENGGIGYQIFTPNPFIYKERSQETI FTYHHIREDAFSLYGFSTREEKALFTKLLNVTGIGPKGALAILGSGDPGAVIQAIENE DEAFLVKFPGVGKKTARQIILDLKGKLADVVPEMIENLFNHEERLEKQTAETALEEAL EALRVLGYAEKEIKKVLPHLKEEIGLTTDQYVKKALQKLLK*" gene complement(2701763..2702368) /gene="ruvA" /locus_tag="BSU_27740" /old_locus_tag="BSU27740" promotor_-10 complement(2702387..2702406) /Source="Nicolas_upshift_promotors" /id="U2143" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.915084915084915" /psig=1 /xcortree=2553 /SigmaFactorBS="aaagaatgagagagaagcgaacatatgttaacttttctatAA GACTTtggctgttttTATGGTACAATGAAGAACAGtcaaagaggtgaatttgcgtgat t" /listShort="ruvA, ruvB, yrzS, queA, tgt, yrbF" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2702403) /Source="Nicolas_upshifts" /id="U2143" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.915084915084915" /psig=1 /xcortree=2553 /SigmaFactorBS="aaagaatgagagagaagcgaacatatgttaacttttctatAA GACTTtggctgttttTATGGTACAATGAAGAACAGtcaaagaggtgaatttgcgtgat t" /listShort="ruvA, ruvB, yrzS, queA, tgt, yrbF" /GFF_Attribute="listLong" S_feature complement(2702405..2702506) /Source="Nicolas_S_feature" /locus_tag="new_2836807_2836908_c" /HighExp="Etha, Heat, S8, S7, S4, S3, S6, S5, Salt, LoTm" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigGF, SigB" /TUshortPSig="0.997, 1" /TUlongSig="SigA" /TUlongPSig=1 /label="S1050" promotor_-35 complement(2702417..2702423) /Source="Nicolas_upshift_promotors" /id="U2143" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.915084915084915" /psig=1 /xcortree=2553 /SigmaFactorBS="aaagaatgagagagaagcgaacatatgttaacttttctatAA GACTTtggctgttttTATGGTACAATGAAGAACAGtcaaagaggtgaatttgcgtgat t" /listShort="ruvA, ruvB, yrzS, queA, tgt, yrbF" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2702507..2703019) /gene="bofC" /locus_tag="BSU_27750" /old_locus_tag="BSU27750" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:10931291, 16049010" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10931291, 16049010; Product type f: factor" /codon_start=1 /transl_table=11 /product="bypass of forespore C, intercompartmental signaling factor" /protein_id="NP_390653.1" /db_xref="EnsemblGenomes-Gn:BSU27750" /db_xref="EnsemblGenomes-Tr:CAB14735" /db_xref="GOA:O05391" /db_xref="InterPro:IPR015050" /db_xref="InterPro:IPR015071" /db_xref="PDB:2BW2" /db_xref="SubtiList:BG11917" /db_xref="UniProtKB/Swiss-Prot:O05391" /translation="MKRFSTAYLLLGILCSAAVFLIGAPSRALGAEVEHYEPLQVHVQ LEKVYLDGDVSIEHKHEKVFSMDDFWAAYAGWTLVEQKKGYVLFRKQMDDISPLSKVN GYIGVSDNGVISTFHGRPEPASEPIQSFFQIDLERLESHMQKNLLKGIPFRTKAEFED VIEHMKTYSG*" gene complement(2702507..2703019) /gene="bofC" /locus_tag="BSU_27750" /old_locus_tag="BSU27750" promotor_-10 complement(2703048..2703059) /Source="Nicolas_upshift_promotors" /id="U2144" /multdbtbs="SigF,SigG" /comp="M8" /sig="SigGF" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=1133 /SigmaFactorBS="gaacggtttgtcagggaaaatgtgcagacaaattttgataaa aCGGTTAAgcagtagcctctttGGTCAAACTAATcataaacgtgtgcaaagaggtgta g" /listShort="bofC, S1050, ruvA, ruvB" /listLong="yrzS, queA, tgt, yrbF" /label="promotor_-10" upshifts complement(2703063) /Source="Nicolas_upshifts" /id="U2144" /multdbtbs="SigF,SigG" /comp="M8" /sig="SigGF" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=1133 /SigmaFactorBS="gaacggtttgtcagggaaaatgtgcagacaaattttgataaa aCGGTTAAgcagtagcctctttGGTCAAACTAATcataaacgtgtgcaaagaggtgta g" /listShort="bofC, S1050, ruvA, ruvB" /listLong="yrzS, queA, tgt, yrbF" CDS complement(2703067..2704374) /gene="csbX" /locus_tag="BSU_27760" /old_locus_tag="BSU27760" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 9099855, 14638426, 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative catecholate siderophose exporter" /protein_id="NP_390654.2" /db_xref="EnsemblGenomes-Gn:BSU27760" /db_xref="EnsemblGenomes-Tr:CAB14736" /db_xref="GOA:O05390" /db_xref="InterPro:IPR004748" /db_xref="InterPro:IPR011701" /db_xref="InterPro:IPR020846" /db_xref="InterPro:IPR036259" /db_xref="SubtiList:BG11922" /db_xref="UniProtKB/Swiss-Prot:O05390" /translation="MNTVHAKGNVLNKIGIPSHMVWGYIGVVIFMVGDGLEQGWLSPF LVDHGLSMQQSASLFTMYGIAVTISAWLSGTFVQTWGPRKTMTVGLLAFILGSAAFIG WAIPHMYYPALLGSYALRGLGYPLFAYSFLVWVSYSTSQNILGKAVGWFWFMFTCGLN VLGPFYSSYAVPAFGEINTLWSALLFVAAGGILALFFNKDKFTPIQKQDQPKWKELSK AFTIMFENPKVGIGGVVKTINAIGQFGFAIFLPTYLARYGYSVSEWLQIWGTLFFVNI VFNIIFGAVGDKLGWRNTVMWFGGVGCGIFTLALYYTPQLIGHQYWVLMIIACCYGAA LAGYVPLSALLPTLAPDNKGAAMSVLNLGSGLCAFIAPGIVSLFIGPLGAGGVIWIFA ALYFFSAFLTRFLTISEQSTDVYTEERFVRENVQTNFDKTVKQ*" gene complement(2703067..2704374) /gene="csbX" /locus_tag="BSU_27760" /old_locus_tag="BSU27760" promotor_-35 complement(2703074..2703080) /Source="Nicolas_upshift_promotors" /id="U2144" /multdbtbs="SigF,SigG" /comp="M8" /sig="SigGF" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=1133 /SigmaFactorBS="gaacggtttgtcagggaaaatgtgcagacaaattttgataaa aCGGTTAAgcagtagcctctttGGTCAAACTAATcataaacgtgtgcaaagaggtgta g" /listShort="bofC, S1050, ruvA, ruvB" /listLong="yrzS, queA, tgt, yrbF" /label="promotor_-35" downshifts complement(2704328) /Source="Nicolas_upshifts" /id="D1420" /incds=0 /nref=2 /ntot=80 /MaxReadThrough="7.18585" /MaxDrop="3.0235" /score="-6.29978124" /energy="-14.3" /TU="U2145,U2146" /idTUdmin="U2146" /TUdmin="-1793" /isTUend="FALSE" promotor_-10 complement(2704398..2704416) /Source="Nicolas_upshift_promotors" /id="U2145" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=262 /SigmaFactorBS="ttgagcacactgaaaaaatcgctttttaatctaacaGGATTA CaattcagcaagcttGGGTATATACTCCATTGATactttaagtaggcggtggagaaaa t" /listShort="csbX, bofC, S1050, ruvA, ruvB, yrzS, queA, tgt" /listLong="yrbF" /label="promotor_-10" upshifts complement(2704413) /Source="Nicolas_upshifts" /id="U2145" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=262 /SigmaFactorBS="ttgagcacactgaaaaaatcgctttttaatctaacaGGATTA CaattcagcaagcttGGGTATATACTCCATTGATactttaagtaggcggtggagaaaa t" /listShort="csbX, bofC, S1050, ruvA, ruvB, yrzS, queA, tgt" /listLong="yrbF" promotor_-35 complement(2704431..2704437) /Source="Nicolas_upshift_promotors" /id="U2145" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=262 /SigmaFactorBS="ttgagcacactgaaaaaatcgctttttaatctaacaGGATTA CaattcagcaagcttGGGTATATACTCCATTGATactttaagtaggcggtggagaaaa t" /listShort="csbX, bofC, S1050, ruvA, ruvB, yrzS, queA, tgt" /listLong="yrbF" /label="promotor_-35" CDS complement(2704445..2705470) /gene="yrbE" /locus_tag="BSU_27770" /old_locus_tag="BSU27770" /EC_number="1.-.-.-" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 28043209; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative inositol-related oxidoreductase" /protein_id="NP_390655.1" /db_xref="EnsemblGenomes-Gn:BSU27770" /db_xref="EnsemblGenomes-Tr:CAB14737" /db_xref="GOA:O05389" /db_xref="InterPro:IPR000683" /db_xref="InterPro:IPR004104" /db_xref="InterPro:IPR030827" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG12280" /db_xref="UniProtKB/Swiss-Prot:O05389" /translation="MTKQIVTGIIGAGRIGKLHVQNISRIPHMKIKAISDIQASRIKS WADSHQIEYITSDYRDLLHDPDIDAIFICSPTAVHAQMIKEAAEAKKHIFCEKPVSFS LDETSEALAAVRKHGVTLQVGFNRRFDPHFKKIKTIVENGEIGTPHLLKITSRDPEPP NIDYVRTSGGLFMDMSIHDFDMARYIMGSEVTEVYAKGAALVNPSFAELGDIDTAVIT LTFENGAMAVIDNSRQAVYGYDQRVEVFGTKGSAAADNSRPTTVEVSTADFVMKDKPH FFFLERYKDSYEEEILRFAEAIGTNQETPCTGNDGLQAGRIARAAQQSLAFGMPVSIE HTEKIAF*" gene complement(2704445..2705470) /gene="yrbE" /locus_tag="BSU_27770" /old_locus_tag="BSU27770" promotor_-10 complement(2705507..2705526) /Source="Nicolas_upshift_promotors" /id="U2146" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.993006993006993" /psig=1 /xcortree=328 /SigmaFactorBS="gaattgtgataaaagagacatagaacgtttaatttccatTCT TGAAAagcgcttacaaatgGGATAGTATTAATTTTAAATaaagcgctttcgtgaatga t" /listShort="yrbE, csbX, bofC" /listLong="S1050, ruvA, ruvB" /label="promotor_-10" upshifts complement(2705527) /Source="Nicolas_upshifts" /id="U2146" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.993006993006993" /psig=1 /xcortree=328 /SigmaFactorBS="gaattgtgataaaagagacatagaacgtttaatttccatTCT TGAAAagcgcttacaaatgGGATAGTATTAATTTTAAATaaagcgctttcgtgaatga t" /listShort="yrbE, csbX, bofC" /listLong="S1050, ruvA, ruvB" promotor_-35 complement(2705541..2705548) /Source="Nicolas_upshift_promotors" /id="U2146" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.993006993006993" /psig=1 /xcortree=328 /SigmaFactorBS="gaattgtgataaaagagacatagaacgtttaatttccatTCT TGAAAagcgcttacaaatgGGATAGTATTAATTTTAAATaaagcgctttcgtgaatga t" /listShort="yrbE, csbX, bofC" /listLong="S1050, ruvA, ruvB" /label="promotor_-35" promotor_-35 2705596..2705603 /Source="Nicolas_upshift_promotors" /id="U2147" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.661338661338661" /psig="0.997002997002997" /xcortree=1538 /SigmaFactorBS="ctatgtctcttttatcacaattcatgcttatAAGTAGCCttc ttcttcaagaCCAGATACACTAGAATTAGGctctttttcctgaacagtttatgatttt c" /listShort="yrzF" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2705617..2705636 /Source="Nicolas_upshift_promotors" /id="U2147" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.661338661338661" /psig="0.997002997002997" /xcortree=1538 /SigmaFactorBS="ctatgtctcttttatcacaattcatgcttatAAGTAGCCttc ttcttcaagaCCAGATACACTAGAATTAGGctctttttcctgaacagtttatgatttt c" /listShort="yrzF" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2705625 /Source="Nicolas_upshifts" /id="U2147" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.661338661338661" /psig="0.997002997002997" /xcortree=1538 /SigmaFactorBS="ctatgtctcttttatcacaattcatgcttatAAGTAGCCttc ttcttcaagaCCAGATACACTAGAATTAGGctctttttcctgaacagtttatgatttt c" /listShort="yrzF" /GFF_Attribute="listLong" promotor_-35 2705657..2705662 /Source="Nicolas_upshift_promotors" /id="U2148" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.993006993006993" /psig="0.993006993006993" /xcortree=1056 /SigmaFactorBS="tcaagaccagatacactagaattaggctctttttcctgaaca gtttATGATTttcctataaacagctGCATAAAATAGAGCAAAGAaggtgaatgaaatg c" /listShort="yrzF" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 2705671 /Source="Nicolas_upshifts" /id="U2148" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.993006993006993" /psig="0.993006993006993" /xcortree=1056 /SigmaFactorBS="tcaagaccagatacactagaattaggctctttttcctgaaca gtttATGATTttcctataaacagctGCATAAAATAGAGCAAAGAaggtgaatgaaatg c" /listShort="yrzF" /GFF_Attribute="listLong" promotor_-10 2705678..2705696 /Source="Nicolas_upshift_promotors" /id="U2148" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.993006993006993" /psig="0.993006993006993" /xcortree=1056 /SigmaFactorBS="tcaagaccagatacactagaattaggctctttttcctgaaca gtttATGATTttcctataaacagctGCATAAAATAGAGCAAAGAaggtgaatgaaatg c" /listShort="yrzF" /GFF_Attribute="listLong" /label="promotor_-10" CDS 2705708..2706355 /gene="yrzF" /locus_tag="BSU_27785" /old_locus_tag="BSU27785" /EC_number="2.7.11.1" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative serine/threonine-protein kinase" /protein_id="NP_390656.2" /db_xref="EnsemblGenomes-Gn:BSU27785" /db_xref="EnsemblGenomes-Tr:CAB14738" /db_xref="GOA:O32057" /db_xref="InterPro:IPR011009" /db_xref="InterPro:IPR017441" /db_xref="SubtiList:BG13816" /db_xref="UniProtKB/Swiss-Prot:O32057" /translation="MLTKAEALAHTVIYRKNSRFDKVKEKSEELTLIGKGRSAYVFAL TEGGRKMALKVFFPEYQATAVKEAAIYEKLAGSAFYPDIYETGDSFILMEYIKGETFY NCLKKGIAISDDMIQQVEEALSDARAAGLNPSDIHLRNLILTETGAVRVIDVARFEQT KTCTQWDDLKSAYHALYKKPIFPKKIPGFWLEIIAFLYKKDWFQKHFAQRKRKYS*" gene 2705708..2706355 /gene="yrzF" /locus_tag="BSU_27785" /old_locus_tag="BSU27785" S_feature complement(2706030..2706363) /Source="Nicolas_S_feature" /locus_tag="new_2840432_2840765_c" /HighExp="LPhT, S8, BI, S7, S6, C30, Sw, BC, Gly, C90" /AntisenseName="yrzF" /AntisenseCor="0.348831504804749" /AntisenseRegPval="-8.4" /CDS_PredictionProba="NA" /TUshortSig="NA" /TUshortPSig="NA" /TUlongSig="NA" /TUlongPSig="NA" /label="S1051" downshifts 2706334 /Source="Nicolas_upshifts" /id="D1421" /incds=0 /nref=29 /ntot=228 /MaxReadThrough="2.4121" /MaxDrop="5.05737" /score="20.8102477" /energy="-18.2" /TU="NA" /idTUdmin="U2147" /TUdmin="-20" /isTUend="TRUE" S_feature complement(2706365..2706562) /Source="Nicolas_S_feature" /locus_tag="new_2840767_2840964_c" /HighExp="LPhT, BI, B60, S8, Gly, S7, S6, B36, S5, LBGstat" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.99984200000000001" /TUshortSig="Sig-" /TUshortPSig="0.032" /TUlongSig="NA" /TUlongPSig="NA" /label="S1052" CDS complement(2706401..2706523) /locus_tag="BSU_27786" /old_locus_tag="BSU27786" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_009513992.1" /db_xref="EnsemblGenomes-Gn:BSU27786" /db_xref="EnsemblGenomes-Tr:CCQ48603" /db_xref="UniProtKB/TrEMBL:L8EAY3" /translation="MEKTYCHSGEKDPEAVYLTVRGYRIKLSPEQMKLISAVRK*" gene complement(2706401..2706523) /locus_tag="BSU_27786" /old_locus_tag="BSU27786" downshifts complement(2706408) /Source="Nicolas_upshifts" /id="D1422" /incds=0 /nref=3 /ntot=19 /MaxReadThrough="4.39913" /MaxDrop="4.52186" /score="39.5790138" /energy="-18.2" /TU="NA" /idTUdmin="U2149" /TUdmin=0 /isTUend="TRUE" upshifts complement(2706571) /Source="Nicolas_upshifts" /id="U2149" /multdbtbs="-" /comp="M6" /sig="Sig-" /pcomp="0.965034965034965" /psig="0.031968031968032" /xcortree=11 /SigmaFactorBS="cattttactatatatcggattcatataaTCTTTACAtttctt TAAAATTACCTCAATAAAgcaatgataagatgaaataaagccaataaagggtgagggg a" /listShort="S1052" /GFF_Attribute="listLong" promotor_-10 complement(2706572..2706589) /Source="Nicolas_upshift_promotors" /id="U2149" /multdbtbs="-" /comp="M6" /sig="Sig-" /pcomp="0.965034965034965" /psig="0.031968031968032" /xcortree=11 /SigmaFactorBS="cattttactatatatcggattcatataaTCTTTACAtttctt TAAAATTACCTCAATAAAgcaatgataagatgaaataaagccaataaagggtgagggg a" /listShort="S1052" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 complement(2706596..2706603) /Source="Nicolas_upshift_promotors" /id="U2149" /multdbtbs="-" /comp="M6" /sig="Sig-" /pcomp="0.965034965034965" /psig="0.031968031968032" /xcortree=11 /SigmaFactorBS="cattttactatatatcggattcatataaTCTTTACAtttctt TAAAATTACCTCAATAAAgcaatgataagatgaaataaagccaataaagggtgagggg a" /listShort="S1052" /GFF_Attribute="listLong" /label="promotor_-35" CDS 2706608..2706898 /gene="yrzH" /locus_tag="BSU_27800" /old_locus_tag="BSU27800" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="NP_390658.2" /db_xref="EnsemblGenomes-Gn:BSU27800" /db_xref="EnsemblGenomes-Tr:CAB14740" /db_xref="SubtiList:BG13818" /db_xref="UniProtKB/Swiss-Prot:O32059" /translation="MNPIYSKMREKKGESHIKTENTLSLDAARGELVNEKTLVKRTIY WNYPDSRPAVTWINHNTVKIGNQTLHLDTDETYDWRKDDHWIREEPPQASVR*" gene 2706608..2706898 /gene="yrzH" /locus_tag="BSU_27800" /old_locus_tag="BSU27800" misc_feature 2706619..2706638 /Source="Nicolas_upshift_promotors" /id="U2150" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.462537462537463" /psig="0.903096903096903" /xcortree=657 /SigmaFactorBS="atcttatcattgctttattgaggtaattttaaagaaatgtaa agattatatgaatccgatATATAGTAAAATGAGAGAAAaaaagggagagagtcacatt a" /listShort="S1053, yrzH, yrzT" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" S_feature 2706619..2706766 /Source="Nicolas_S_feature" /locus_tag="new_2841021_2841168" /HighExp="T3.30H, T4.0H, T3.0H, T2.0H, T2.30H, T5.0H, M9-stat, S7, T1.30H, B60" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.99999400000000005" /TUshortSig="SigA" /TUshortPSig="0.903" /TUlongSig="NA" /TUlongPSig="NA" /label="S1053" upshifts 2706619 /Source="Nicolas_upshifts" /id="U2150" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.462537462537463" /psig="0.903096903096903" /xcortree=657 /SigmaFactorBS="atcttatcattgctttattgaggtaattttaaagaaatgtaa agattatatgaatccgatATATAGTAAAATGAGAGAAAaaaagggagagagtcacatt a" /listShort="S1053, yrzH, yrzT" /GFF_Attribute="listLong" CDS 2706905..2707045 /gene="yrzT" /locus_tag="BSU_27809" /old_locus_tag="BSU27809" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_003097769.1" /db_xref="EnsemblGenomes-Gn:BSU27809" /db_xref="EnsemblGenomes-Tr:CAX52675" /db_xref="GOA:C0H464" /db_xref="UniProtKB/Swiss-Prot:C0H464" /translation="MNKMNGTNDEKHFNHFVIALSFIYGLTELGYLLLKDFITIAISL PL*" gene 2706905..2707045 /gene="yrzT" /locus_tag="BSU_27809" /old_locus_tag="BSU27809" downshifts 2707034 /Source="Nicolas_upshifts" /id="D1423" /incds=0 /nref=139 /ntot=241 /MaxReadThrough="0.64189" /MaxDrop="4.74983" /score="23.2933855" /energy="-9.9" /TU="NA" /idTUdmin="U2150" /TUdmin="-2" /isTUend="TRUE" promotor_-35 2707094..2707100 /Source="Nicolas_upshift_promotors" /id="U2151" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.992007992007992" /psig="0.992007992007992" /xcortree=1083 /SigmaFactorBS="cgtagtcgatacgccgcgttttttctttttcccttcctCTTC TTAttgataattacaggTCATATAATGTGACAAATCgattgtagaaatagttcgatta g" /listShort="yrbD, S1054" /GFF_Attribute="listLong" /label="promotor_-35" promotor_no_box 2707108..2707208 /Source="Nicolas_upshift_promotors" /id="U2152" /multdbtbs="-" /comp="M21" /sig="Sig-" /pcomp="0.383616383616384" /psig="0.376623376623377" /xcortree=317 /SigmaFactorBS="ttacaggtcatataatgtgacaaatcgattgtagaaatagtt cgattagaccaaaatcctttttatacatgtattcgaatttgaagtgagggggaagctt g" /listShort="yrbD" /GFF_Attribute="listLong" /label="promotor_no_box" promotor_-10 2707115..2707133 /Source="Nicolas_upshift_promotors" /id="U2151" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.992007992007992" /psig="0.992007992007992" /xcortree=1083 /SigmaFactorBS="cgtagtcgatacgccgcgttttttctttttcccttcctCTTC TTAttgataattacaggTCATATAATGTGACAAATCgattgtagaaatagttcgatta g" /listShort="yrbD, S1054" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2707116 /Source="Nicolas_upshifts" /id="U2151" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.992007992007992" /psig="0.992007992007992" /xcortree=1083 /SigmaFactorBS="cgtagtcgatacgccgcgttttttctttttcccttcctCTTC TTAttgataattacaggTCATATAATGTGACAAATCgattgtagaaatagttcgatta g" /listShort="yrbD, S1054" /GFF_Attribute="listLong" upshifts 2707168 /Source="Nicolas_upshifts" /id="U2152" /multdbtbs="-" /comp="M21" /sig="Sig-" /pcomp="0.383616383616384" /psig="0.376623376623377" /xcortree=317 /SigmaFactorBS="ttacaggtcatataatgtgacaaatcgattgtagaaatagtt cgattagaccaaaatcctttttatacatgtattcgaatttgaagtgagggggaagctt g" /listShort="yrbD" /GFF_Attribute="listLong" CDS 2707209..2708663 /gene="alaP" /locus_tag="BSU_27810" /old_locus_tag="BSU27810" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1c: Function from experimental evidences in the studied genus; PubMedId: 1400476, 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="sodium/proton-dependent alanine transporter" /protein_id="NP_390659.2" /db_xref="EnsemblGenomes-Gn:BSU27810" /db_xref="EnsemblGenomes-Tr:CAB14741" /db_xref="GOA:O32060" /db_xref="InterPro:IPR001463" /db_xref="SubtiList:BG13784" /db_xref="UniProtKB/Swiss-Prot:O32060" /translation="MADFVASLNAVLWSTPVIYILLGIGFAFSIMTRFLQVRHLKEMI VQMFKGKSSEAGVSSFQALSIALSGRVGTGNIAGVATAIAFGGPGAVFWMWAIAFIGA ASAFVESTLAQIYKVKQDGQYRGGPAYYIEKGLGIKWFAVLFAAAALIAMAFLMPGVQ SNSIAAGIQNAFGISPFVTGCGLVLLLGFIIFGGVKRIANAAQMIVPFMAIGYILLSL IIIVMNVSELPAVISLIFKSAFALDSAFGGLIGMAISWGVKRGIYSNEAGQGTGPHPA AAAEVSHPVKQGLVQAFSVYIDTLFVCSATAFMILFTGMYNTQAADGSFIVHQLKGVE AGPGFTQAAIDSVLPGFGAGFVAIALFFFAFTTIMAYYYIAETNIAYLARGRESKWAM LGLKLIILAATFYGTVKTASLAWALGDAGLGIMVWLNVIAIVLLAKPALLALKDYERQ KKQGLDPIFDPKALGIKNADFWEKEYTHESERVS*" gene 2707209..2708663 /gene="alaP" /locus_tag="BSU_27810" /old_locus_tag="BSU27810" downshifts 2708664 /Source="Nicolas_upshifts" /id="D1424" /incds=0 /nref=6 /ntot=43 /MaxReadThrough="5.01314" /MaxDrop="4.4617" /score="6.86850608" /energy="-10.8" /TU="U2151" /idTUdmin="U2152" /TUdmin=0 /isTUend="TRUE" CDS complement(2708704..2709426) /gene="yrbC" /locus_tag="BSU_27820" /old_locus_tag="BSU27820" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 12060744, 18641136, 20647113; Product type f: factor" /codon_start=1 /transl_table=11 /product="putative factor regulating gene expression" /protein_id="NP_390660.1" /db_xref="EnsemblGenomes-Gn:BSU27820" /db_xref="EnsemblGenomes-Tr:CAB14742" /db_xref="GOA:P94447" /db_xref="InterPro:IPR002876" /db_xref="InterPro:IPR017856" /db_xref="InterPro:IPR026564" /db_xref="InterPro:IPR029072" /db_xref="SubtiList:BG13783" /db_xref="UniProtKB/Swiss-Prot:P94447" /translation="MAGHSKWKNIQKRKNAQDAKRGKIFMKLAKEIYVAAKEGGADPE ANSALRLVIEKAKGANMPNENIDRAIKKAAGGQDGSSYEEITYEGYGPSGIAVMVECV TDNKNRTASNVRTAFNKNGGSLGESGCVAFLFERKGFITIDRTERQIEEDELMLDVLE AGGEELRIEEDLYEVFTEPEHFEEVKTALESKYLISSAEVTMLPNTYAEADDQAVEKL ETLIDVLEDDDDVQEVYTNYRS*" gene complement(2708704..2709426) /gene="yrbC" /locus_tag="BSU_27820" /old_locus_tag="BSU27820" S_feature 2708709..2709130 /Source="Nicolas_S_feature" /locus_tag="new_2843111_2843532" /HighExp="S8, S6, S7, BT, C30, S5, S4, LoTm, C90, S3" /AntisenseName="yrbC" /AntisenseCor="-8.4330852334841305E-2" /AntisenseRegPval="-0.8" /CDS_PredictionProba="NA" /TUshortSig="SigEF" /TUshortPSig="0.992" /TUlongSig="NA" /TUlongPSig="NA" /label="S1054" downshifts complement(2708720) /Source="Nicolas_upshifts" /id="D1425" /incds=0 /nref=11 /ntot=164 /MaxReadThrough="3.2014" /MaxDrop="3.66865" /score="23.9031001" /energy="-16" /TU="U2153" /idTUdmin="U2153" /TUdmin="-574" /isTUend="FALSE" promotor_-10 complement(2709449..2709468) /Source="Nicolas_upshift_promotors" /id="U2153" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.986013986013986" /psig=1 /xcortree=1965 /SigmaFactorBS="aggaagggctgccggaagtgatattcggcagccttttTCTTT GCAtcagcgaacatttCCCATTAAAGTGTACATAGAaaatgtaaaagaaggtgaaaac a" /listShort="yrbC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2709466) /Source="Nicolas_upshifts" /id="U2153" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.986013986013986" /psig=1 /xcortree=1965 /SigmaFactorBS="aggaagggctgccggaagtgatattcggcagccttttTCTTT GCAtcagcgaacatttCCCATTAAAGTGTACATAGAaaatgtaaaagaaggtgaaaac a" /listShort="yrbC" /GFF_Attribute="listLong" promotor_-35 complement(2709482..2709489) /Source="Nicolas_upshift_promotors" /id="U2153" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.986013986013986" /psig=1 /xcortree=1965 /SigmaFactorBS="aggaagggctgccggaagtgatattcggcagccttttTCTTT GCAtcagcgaacatttCCCATTAAAGTGTACATAGAaaatgtaaaagaaggtgaaaac a" /listShort="yrbC" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2709529..2710125) /gene="sgpA" /locus_tag="BSU_27830" /old_locus_tag="BSU27830" /function="16.13: Shape" /function="16.5: Explore" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:9770294, 10438771, 12562816, 17322312" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9770294, 10438771, 12562816, 17322312; Product type f: factor" /codon_start=1 /transl_table=11 /product="spore germination protein" /protein_id="NP_390661.2" /db_xref="EnsemblGenomes-Gn:BSU27830" /db_xref="EnsemblGenomes-Tr:CAB14743" /db_xref="GOA:P94446" /db_xref="InterPro:IPR019076" /db_xref="SubtiList:BG13782" /db_xref="UniProtKB/Swiss-Prot:P94446" /translation="MGKKMTIASLILMTAGLTACGANDNAMNDTRNNGNTRPIGYYTN ENDADRQGDGIDHDGPVSELMEDQNDGNRNTTNVNNRDRVTADDRVPLATDGTYNNTN NRNMNRNAANNGYDNQENRRLAAKIANRVKQVKNVNDTQVMVSDDRVVIAVKSHREFT KSDRDNVVKAARNYANGRDVQVSTDKGLFRKLHKMNNR*" gene complement(2709529..2710125) /gene="sgpA" /locus_tag="BSU_27830" /old_locus_tag="BSU27830" downshifts complement(2709544) /Source="Nicolas_upshifts" /id="D1426" /incds=0 /nref=96 /ntot=172 /MaxReadThrough="2.47709" /MaxDrop="7.18444" /score="23.9031001" /energy="-16" /TU="NA" /idTUdmin="U2154" /TUdmin="-12" /isTUend="TRUE" promotor_-10 complement(2710168..2710179) /Source="Nicolas_upshift_promotors" /id="U2154" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=845 /SigmaFactorBS="cagatcactgccaaatggagagaactgacaCGCTTAAcatgc cccccatacGCACATGATAAAagcgagcaaacatgctcaattcgtccacggggggttt t" /listShort="coxA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2710170) /Source="Nicolas_upshifts" /id="U2154" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=845 /SigmaFactorBS="cagatcactgccaaatggagagaactgacaCGCTTAAcatgc cccccatacGCACATGATAAAagcgagcaaacatgctcaattcgtccacggggggttt t" /listShort="coxA" /GFF_Attribute="listLong" S_feature complement(2710172..2710236) /Source="Nicolas_S_feature" /locus_tag="new_2844574_2844638_c" /HighExp="B36, LoTm, S8, S6, S5, BT, B60, S4, S7, S3" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigEF, SigEF, SigA" /TUshortPSig="1, 0.999, 0.996" /TUlongSig="NA" /TUlongPSig="NA" /label="S1055" promotor_-35 complement(2710194..2710200) /Source="Nicolas_upshift_promotors" /id="U2154" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=845 /SigmaFactorBS="cagatcactgccaaatggagagaactgacaCGCTTAAcatgc cccccatacGCACATGATAAAagcgagcaaacatgctcaattcgtccacggggggttt t" /listShort="coxA" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2710273..2711436) /gene="safA" /locus_tag="BSU_27840" /old_locus_tag="BSU27840" /function="16.13: Shape" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:10438771, 10714986, 10714992, 11040425, 15901704, 26953338" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10438771, 10714986, 10714992, 11040425, 15901704, 26953338; Product type f : factor" /codon_start=1 /transl_table=11 /product="morphogenetic protein associated with SpoVID" /protein_id="NP_390662.1" /db_xref="EnsemblGenomes-Gn:BSU27840" /db_xref="EnsemblGenomes-Tr:CAB14744" /db_xref="GOA:O32062" /db_xref="InterPro:IPR014248" /db_xref="InterPro:IPR018392" /db_xref="InterPro:IPR036779" /db_xref="SubtiList:BG13781" /db_xref="UniProtKB/Swiss-Prot:O32062" /translation="MKIHIVQKGDSLWKIAEKYGVDVEEVKKLNTQLSNPDLIMPGMK IKVPSEGVPVRKEPKAGKSPAAGSVKQEHPYAKEKPKSVVDVEDTKPKEKKSMPYVPP MPNLQENVYPEADVNDYYDMKQLFQPWSPPKPEEPKKHHDGNMDHMYHMQDQFPQQEA MSNMENANYPNMPNMPKAPEVGGIEEENVHHTVPNMPMPAVQPYYHYPAHFVPCPVPV SPILPGSGLCYPYYPAQAYPMHPMHGYQPGFVSPQYDPGYENQHHENSHHGHYGSYGA PQYASPAYGSPYGHMPYGPYYGTPQVMGAYQPAAAHGYMPYKDHDDCGCDGDHQPYFS APGHSGMGAYGSPNMPYGTANPNPNPYSAGVSMPMTNQPSVNQMFGRPEEENE*" gene complement(2710273..2711436) /gene="safA" /locus_tag="BSU_27840" /old_locus_tag="BSU27840" downshifts complement(2710281) /Source="Nicolas_upshifts" /id="D1427" /incds=0 /nref=34 /ntot=189 /MaxReadThrough="5.61903" /MaxDrop="3.9565" /score="38.1347732" /energy="-11.1" /TU="U2155,U2156,U2159" /idTUdmin="U2154" /TUdmin="-749" /isTUend="FALSE" S_feature complement(2711437..2711512) /Source="Nicolas_S_feature" /locus_tag="new_2845839_2845914_c" /HighExp="S5, S4, B36, LoTm, S3, B60, S7, S6, Pyr, T5.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigEF, SigEF, SigA" /TUshortPSig="1, 0.999, 0.996" /TUlongSig="NA" /TUlongPSig="NA" /label="S1056" promotor_-10 complement(2711488..2711506) /Source="Nicolas_upshift_promotors" /id="U2155" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1106 /SigmaFactorBS="gaatgctttcgatcacgtagatcagaaatattttcccttcct ttaCTCATAacttcttttgttcagGCATATGTTGTGAAGAAACatattgtaatcacag c" /listShort="S1056, safA, S1055, coxA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2711512) /Source="Nicolas_upshifts" /id="U2155" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1106 /SigmaFactorBS="gaatgctttcgatcacgtagatcagaaatattttcccttcct ttaCTCATAacttcttttgttcagGCATATGTTGTGAAGAAACatattgtaatcacag c" /listShort="S1056, safA, S1055, coxA" /GFF_Attribute="listLong" promotor_-35 complement(2711522..2711527) /Source="Nicolas_upshift_promotors" /id="U2155" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1106 /SigmaFactorBS="gaatgctttcgatcacgtagatcagaaatattttcccttcct ttaCTCATAacttcttttgttcagGCATATGTTGTGAAGAAACatattgtaatcacag c" /listShort="S1056, safA, S1055, coxA" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2711553..2712659) /gene="nadA" /locus_tag="BSU_27850" /old_locus_tag="BSU27850" /EC_number="2.5.1.72" /function="16.10: Respire" /experiment="publication(s) with functional evidences, PMID:15898769, 15937336, 15967443, 18959769, 26455817" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15898769, 15937336, 15967443, 18959769, 26455817; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="quinolinate synthetase" /protein_id="NP_390663.1" /db_xref="EnsemblGenomes-Gn:BSU27850" /db_xref="EnsemblGenomes-Tr:CAB14745" /db_xref="GOA:Q9KWZ1" /db_xref="InterPro:IPR003473" /db_xref="InterPro:IPR023515" /db_xref="InterPro:IPR036094" /db_xref="SubtiList:BG12629" /db_xref="UniProtKB/Swiss-Prot:Q9KWZ1" /translation="MSILDVIKQSNDMMPESYKELSRKDMETRVAAIKKKFGSRLFIP GHHYQKDEVIQFADQTGDSLQLAQVAEKNKEADYIVFCGVHFMAETADMLTSEQQTVV LPDMRAGCSMADMADMQQTNRAWKKLQHIFGDTIIPLTYVNSTAEIKAFVGKHGGATV TSSNAKKVLEWAFTQKKRILFLPDQHLGRNTAYDLGIALEDMAVWDPMKDELVAESGH TNVKVILWKGHCSVHEKFTTKNIHDMRERDPDIQIIVHPECSHEVVTLSDDNGSTKYI IDTINQAPAGSKWAIGTEMNLVQRIIHEHPDKQIESLNPDMCPCLTMNRIDLPHLLWS LEQIEKGEPSGVIKVPKAIQEDALLALNRMLSIT*" gene complement(2711553..2712659) /gene="nadA" /locus_tag="BSU_27850" /old_locus_tag="BSU27850" promotor_-10 complement(2712235..2712253) /Source="Nicolas_upshift_promotors" /id="U2156" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1174 /SigmaFactorBS="gacatggctgacatgcagcagaccaatagggcatggaagaag cttcAGCATAtatttggagatacgaTCATACCTTTAACTTATGTgaactccactgcgg a" /listShort="S1056, safA, S1055, coxA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2712260) /Source="Nicolas_upshifts" /id="U2156" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1174 /SigmaFactorBS="gacatggctgacatgcagcagaccaatagggcatggaagaag cttcAGCATAtatttggagatacgaTCATACCTTTAACTTATGTgaactccactgcgg a" /listShort="S1056, safA, S1055, coxA" /GFF_Attribute="listLong" promotor_-35 complement(2712269..2712274) /Source="Nicolas_upshift_promotors" /id="U2156" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1174 /SigmaFactorBS="gacatggctgacatgcagcagaccaatagggcatggaagaag cttcAGCATAtatttggagatacgaTCATACCTTTAACTTATGTgaactccactgcgg a" /listShort="S1056, safA, S1055, coxA" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 2712571 /Source="Nicolas_upshifts" /id="U2157" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.993006993006993" /psig=0 /xcortree=25 /SigmaFactorBS="ttttgataatgatggcctggtataaagagcctgctgccgaac tttttcttaatggcggcaaCGCGcgtttccatatcctttctcgatagttctttataac t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" misc_feature 2712572..2712575 /Source="Nicolas_upshift_promotors" /id="U2157" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.993006993006993" /psig=0 /xcortree=25 /SigmaFactorBS="ttttgataatgatggcctggtataaagagcctgctgccgaac tttttcttaatggcggcaaCGCGcgtttccatatcctttctcgatagttctttataac t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" CDS complement(2712646..2713515) /gene="nadC" /locus_tag="BSU_27860" /old_locus_tag="BSU27860" /EC_number="2.4.2.19" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 8419294, 28618168; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="nicotinate-nucleotide pyrophosphorylase (quinolinate phosphoribosyltransferase)" /protein_id="NP_390664.1" /db_xref="EnsemblGenomes-Gn:BSU27860" /db_xref="EnsemblGenomes-Tr:CAB14746" /db_xref="GOA:P39666" /db_xref="InterPro:IPR002638" /db_xref="InterPro:IPR004393" /db_xref="InterPro:IPR013785" /db_xref="InterPro:IPR022412" /db_xref="InterPro:IPR027277" /db_xref="InterPro:IPR036068" /db_xref="InterPro:IPR037128" /db_xref="SubtiList:BG10868" /db_xref="UniProtKB/Swiss-Prot:P39666" /translation="MNHLQLKKLLNHFFLEDIGTGDLTSQSIFGEQSCEAEIVAKSEG IFAGAAIIKEGFSLLDENVQSILHKKDGDMLHKGEVIAELHGPAAALLSGERVVLNLI QRLSGIATMTREAVRCLDDEQIKICDTRKTTPGLRMLEKYAVRAGGGYNHRFGLYDGI MIKDNHIAACGSILEACKKARQAAGHMVNIEVEIETEEQLREAIAAGADVIMFDNCPP DTVRHFAKLTPANIKTEASGGITLESLPAFKGTGVNYISLGFLTHSVKSLDISMDVTL SNESVEECCYVNS*" gene complement(2712646..2713515) /gene="nadC" /locus_tag="BSU_27860" /old_locus_tag="BSU27860" downshifts 2712740 /Source="Nicolas_upshifts" /id="D1428" /incds=1 /nref=4 /ntot=107 /MaxReadThrough="0.495279999999999" /MaxDrop="3.83418" /score="-8.75482157" /energy="-7.4" /TU="NA" /idTUdmin="U2157" /TUdmin=6 /isTUend="TRUE" CDS complement(2713469..2715064) /gene="nadB" /locus_tag="BSU_27870" /old_locus_tag="BSU27870" /EC_number="1.4.3.16" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:8444804, 16199587, 18959769" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8444804, 16199587, 18959769; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="L-aspartate oxidase" /protein_id="NP_390665.1" /db_xref="EnsemblGenomes-Gn:BSU27870" /db_xref="EnsemblGenomes-Tr:CAB14747" /db_xref="GOA:P38032" /db_xref="InterPro:IPR003953" /db_xref="InterPro:IPR005288" /db_xref="InterPro:IPR015939" /db_xref="InterPro:IPR027477" /db_xref="InterPro:IPR036188" /db_xref="InterPro:IPR037099" /db_xref="SubtiList:BG10867" /db_xref="UniProtKB/Swiss-Prot:P38032" /translation="MSKKTIAVIGSGAAALSLAAAFPPSYEVTVITKKSVKNSNSVYA QGGIAAAYAKDDSIEAHLEDTLYAGCGHNNLAIVADVLHDGKMMVQSLLERGFPFDRN ERGGVCLGREGAHSYNRIFHAGGDATGRLLIDYLLKRINSKIKLIENETAADLLIEDG RCIGVMTKDSKGRLKVRHADEVVLAAGGCGNLFLHHTNDLTVTGDGLSLAYRAGAELT DLEFTQFHPTLLVKNGVSYGLVSEAVRGEGGCLVDENGRRIMAERHPLGDLAPRDIVS RVIHEEMAKGNRVYIDFSAISDFETRFPTITAICEKAGIDIHSGKIPVAPGMHFLMGG VSVNRWGETTVPGLYAIGETACSGLHGANRLASNSLLEALVFGKRAAEHIIQKPVYNR QYQSGLETSVFYEVPDIEGHELQSKMTSHMSILREQSSLIELSIWLHTLPFQEVNVKD ITIRQMELSHLWQTAKLMTFSALLREESRGAHFRTDFPHAEVSWQGRQIVHTKKGTKI RKNEGIWNNESFTAEKITESLFS*" gene complement(2713469..2715064) /gene="nadB" /locus_tag="BSU_27870" /old_locus_tag="BSU27870" promotor_-10 complement(2715092..2715111) /Source="Nicolas_upshift_promotors" /id="U2159" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.97002997002997" /psig="0.996003996003996" /xcortree=2917 /SigmaFactorBS="aataaatcatccggtcttcctccatccgttctccataaaaaa cTCTTGAGTttattttatccttgTGTAAATATAGGTGTCAAGAcaggtgtaaacaaca g" /listShort="nadB, nadC, nadA, S1056, safA, S1055, coxA" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 2715092..2715099 /Source="Nicolas_upshift_promotors" /id="U2158" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.999000999001" /psig=1 /xcortree=2916 /SigmaFactorBS="ctttttagacatatgccatcctcctgttgtttacacctgTCT TGACAcctatatttacacaaGGATAAAATAAACTCAAGAGttttttatggagaacgga t" /listShort="nifS, nadR, S1057" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 2715113 /Source="Nicolas_upshifts" /id="U2158" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.999000999001" /psig=1 /xcortree=2916 /SigmaFactorBS="ctttttagacatatgccatcctcctgttgtttacacctgTCT TGACAcctatatttacacaaGGATAAAATAAACTCAAGAGttttttatggagaacgga t" /listShort="nifS, nadR, S1057" /GFF_Attribute="listLong" promotor_-10 2715115..2715134 /Source="Nicolas_upshift_promotors" /id="U2158" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.999000999001" /psig=1 /xcortree=2916 /SigmaFactorBS="ctttttagacatatgccatcctcctgttgtttacacctgTCT TGACAcctatatttacacaaGGATAAAATAAACTCAAGAGttttttatggagaacgga t" /listShort="nifS, nadR, S1057" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2715116) /Source="Nicolas_upshifts" /id="U2159" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.97002997002997" /psig="0.996003996003996" /xcortree=2917 /SigmaFactorBS="aataaatcatccggtcttcctccatccgttctccataaaaaa cTCTTGAGTttattttatccttgTGTAAATATAGGTGTCAAGAcaggtgtaaacaaca g" /listShort="nadB, nadC, nadA, S1056, safA, S1055, coxA" /GFF_Attribute="listLong" promotor_-35 complement(2715126..2715133) /Source="Nicolas_upshift_promotors" /id="U2159" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.97002997002997" /psig="0.996003996003996" /xcortree=2917 /SigmaFactorBS="aataaatcatccggtcttcctccatccgttctccataaaaaa cTCTTGAGTttattttatccttgTGTAAATATAGGTGTCAAGAcaggtgtaaacaaca g" /listShort="nadB, nadC, nadA, S1056, safA, S1055, coxA" /GFF_Attribute="listLong" /label="promotor_-35" CDS 2715167..2716354 /gene="nifS" /locus_tag="BSU_27880" /old_locus_tag="BSU27880" /EC_number="2.8.1.7" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:8444804, 14567704, 16199587, 25447671, 26443755, 28882201" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8444804, 14567704, 16199587, 25447671, 26443755, 28882201; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="desulfurase involved in iron-sulfur clusters forNAD biosynthesis" /protein_id="NP_390666.1" /db_xref="EnsemblGenomes-Gn:BSU27880" /db_xref="EnsemblGenomes-Tr:CAB14748" /db_xref="GOA:P38033" /db_xref="InterPro:IPR000192" /db_xref="InterPro:IPR015421" /db_xref="InterPro:IPR015422" /db_xref="InterPro:IPR015424" /db_xref="InterPro:IPR016454" /db_xref="InterPro:IPR020578" /db_xref="SubtiList:BG10866" /db_xref="UniProtKB/Swiss-Prot:P38033" /translation="MIYLDYAATTPICEEALTVYQKLSMDMYGNASSLHDAGGKAKHI LEYCREKIANIIGGEASGIYFTSGGTESNFLAIQSLLNGLPKTKRHFITTAMEHQSIH NCAAFLEQQGYDVTVIEPNEYGLITEEILLTHIRPETGLVSIQHANSETGIIQPIQHL SSYLHNKGILLHCDAVQTFGKIPINTKNLGVDALSMSSHKIHGPKGVGAVYIRPDVPW KPVYPLTTHEYGFRAGTVNVPGIGAFTAAAELIVSEMEKQISRNEALRTYFLDQIRIR SLPVTLAADTSKAECLPHIIGCFFHSFEGQYVMLECNRSNICISTGSACSAGYHGPSE TMKALRKTEQEALQFIRISFGRHTTAEQLEQLLHTFTVLWEQKKGEFDIDRRIKANGR QQA*" gene 2715167..2716354 /gene="nifS" /locus_tag="BSU_27880" /old_locus_tag="BSU27880" promotor_-10 complement(2715168..2715187) /Source="Nicolas_upshift_promotors" /id="U2160" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=1362 /SigmaFactorBS="atatccatactaagcttctgatatacagtaagggcTTCCTCA CAAataggcgttgtcgcTGCATAATCTAAATAAATCAtccggtcttcctccatccgtt c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2715186) /Source="Nicolas_upshifts" /id="U2160" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=1362 /SigmaFactorBS="atatccatactaagcttctgatatacagtaagggcTTCCTCA CAAataggcgttgtcgcTGCATAATCTAAATAAATCAtccggtcttcctccatccgtt c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(2715202..2715211) /Source="Nicolas_upshift_promotors" /id="U2160" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=1362 /SigmaFactorBS="atatccatactaagcttctgatatacagtaagggcTTCCTCA CAAataggcgttgtcgcTGCATAATCTAAATAAATCAtccggtcttcctccatccgtt c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 2716069..2716074 /Source="Nicolas_upshift_promotors" /id="U2161" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.79020979020979" /psig=1 /xcortree=1922 /SigmaFactorBS="cttcgaaagcagaatgtcttccgcatattatagggtgttttt ttcaCTCATTtgaaggacaaTATGTTATGTTAGAATGTAAtcggagtaatatttgcat t" /listShort="nadR" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 2716083 /Source="Nicolas_upshifts" /id="U2161" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.79020979020979" /psig=1 /xcortree=1922 /SigmaFactorBS="cttcgaaagcagaatgtcttccgcatattatagggtgttttt ttcaCTCATTtgaaggacaaTATGTTATGTTAGAATGTAAtcggagtaatatttgcat t" /listShort="nadR" /GFF_Attribute="listLong" promotor_-10 2716085..2716104 /Source="Nicolas_upshift_promotors" /id="U2161" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.79020979020979" /psig=1 /xcortree=1922 /SigmaFactorBS="cttcgaaagcagaatgtcttccgcatattatagggtgttttt ttcaCTCATTtgaaggacaaTATGTTATGTTAGAATGTAAtcggagtaatatttgcat t" /listShort="nadR" /GFF_Attribute="listLong" /label="promotor_-10" CDS 2716314..2716856 /gene="niaR" /locus_tag="BSU_27890" /old_locus_tag="BSU27890" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:16199587, 18276644" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16199587, 18276644; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional repressor of de novo NAD biosynthesis" /protein_id="NP_390667.2" /db_xref="EnsemblGenomes-Gn:BSU27890" /db_xref="EnsemblGenomes-Tr:CAB14749" /db_xref="GOA:P39667" /db_xref="InterPro:IPR004173" /db_xref="InterPro:IPR013196" /db_xref="InterPro:IPR026043" /db_xref="InterPro:IPR035922" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG10865" /db_xref="UniProtKB/Swiss-Prot:P39667" /translation="MTEELKLMGANRRDQLLLWLKESKSPLTGGELAKKANVSRQVIV QDISLLKAKNVPIIATSQGYVYMDAAAQQHQQAERIIACLHGPERTEEELQLIVDEGV TVKDVKIEHPVYGDLTAAIQVGTRKEVSHFIKKINSTNAAYLSQLTDGVHLHTLTAPD EHRIDQACQALEEAGILIKD*" gene 2716314..2716856 /gene="niaR" /locus_tag="BSU_27890" /old_locus_tag="BSU27890" downshifts 2716839 /Source="Nicolas_upshifts" /id="D1429" /incds=0 /nref=109 /ntot=246 /MaxReadThrough="3.55509" /MaxDrop="5.04771" /score="15.054047" /energy="-5.6" /TU="U2158" /idTUdmin="U2161" /TUdmin="-8" /isTUend="TRUE" CDS complement(2716881..2717738) /gene="pheA" /locus_tag="BSU_27900" /old_locus_tag="BSU27900" /EC_number="4.2.1.51" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:104661, 114523" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 104661, 114523; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="prephenate dehydratase" /protein_id="NP_390668.1" /db_xref="EnsemblGenomes-Gn:BSU27900" /db_xref="EnsemblGenomes-Tr:CAB14750" /db_xref="GOA:P21203" /db_xref="InterPro:IPR001086" /db_xref="InterPro:IPR002912" /db_xref="InterPro:IPR008242" /db_xref="InterPro:IPR018528" /db_xref="SubtiList:BG10914" /db_xref="UniProtKB/Swiss-Prot:P21203" /translation="MKVGYLGPAATFTHLAVSSCFQNGAEHVAYRTIPECIDAAVAGE VDFAFVPLENALEGSVNLTIDYLIHEQPLPIVGEMTLPIHQHLLVHPSRENAWKELDK IYSHSHAIAQCHKFLHRHFPSVPYEYANSTGAAAKFVSDHPELNIGVIANDMAASTYE LKIVKRDIQDYRDNHTRFVILSPDENISFEVNSKLSSRPKTTLMVMLPQDDQSGALHR VLSAFSWRNLNLSKIESRPTKTGLGHYFFIIDIEKAFDDVLIPGAMQELEALGCKVRL LGAYQSYQL*" gene complement(2716881..2717738) /gene="pheA" /locus_tag="BSU_27900" /old_locus_tag="BSU27900" S_feature 2716884..2717593 /Source="Nicolas_S_feature" /locus_tag="new_2851286_2851995" /HighExp="S2, T-5.40H, T3.30H, T-4.40H, GM-0.2, GM-0.1, Pyr, T4.0H, T5.0H, GM 10" /AntisenseName="pheA" /AntisenseCor="-0.15664933741609299" /AntisenseRegPval="-2" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1057" downshifts complement(2716901) /Source="Nicolas_upshifts" /id="D1430" /incds=0 /nref=173 /ntot=247 /MaxReadThrough="1.87872" /MaxDrop="5.15605" /score="13.965695" /energy="-5.6" /TU="NA" /idTUdmin="U2162" /TUdmin=0 /isTUend="TRUE" CDS complement(2717755..2718198) /gene="thrR" /locus_tag="BSU_27910" /old_locus_tag="BSU27910" /experiment="publication(s) with functional evidences, PMID:2537815, 27260660" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 2537815, 27260660; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional repressor of operons hom-thrCB and thrD" /protein_id="NP_390669.1" /db_xref="EnsemblGenomes-Gn:BSU27910" /db_xref="EnsemblGenomes-Tr:CAB14751" /db_xref="InterPro:IPR002912" /db_xref="InterPro:IPR008310" /db_xref="SubtiList:BG10913" /db_xref="UniProtKB/Swiss-Prot:P21204" /translation="MKEETFYLVREDVLPDAMRKTLEVKKLLDRKKADSVADAVQKVD LSRSAFYKYRDAVFPFYTMVKEQIITLFFHLEDRSGALSQLLQAVADSGSNVLSIHQT IPLQGRANVTLSISTSAMEEDIHTLMNKLRKFDFVEKVEILGSGA*" gene complement(2717755..2718198) /gene="thrR" /locus_tag="BSU_27910" /old_locus_tag="BSU27910" CDS complement(2718259..2719545) /gene="obgE" /locus_tag="BSU_27920" /old_locus_tag="BSU27920" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:10781545, 12682299, 15325267, 15827604, 18689482, 20830302, 24844575, 26951678, 28357361" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10781545, 12682299, 15325267, 15827604, 18689482, 20830302, 24844575, 26951678, 28357361; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="ppGpp-binding GTPase involved in cell portioning, DNA repair and ribosome assembly" /protein_id="NP_390670.1" /db_xref="EnsemblGenomes-Gn:BSU27920" /db_xref="EnsemblGenomes-Tr:CAB14752" /db_xref="GOA:P20964" /db_xref="InterPro:IPR005225" /db_xref="InterPro:IPR006073" /db_xref="InterPro:IPR006074" /db_xref="InterPro:IPR006169" /db_xref="InterPro:IPR014100" /db_xref="InterPro:IPR015349" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR031167" /db_xref="InterPro:IPR035101" /db_xref="InterPro:IPR036346" /db_xref="InterPro:IPR036726" /db_xref="PDB:1LNZ" /db_xref="SubtiList:BG10337" /db_xref="UniProtKB/Swiss-Prot:P20964" /translation="MFVDQVKVYVKGGDGGNGMVAFRREKYVPKGGPAGGDGGKGGDV VFEVDEGLRTLMDFRYKKHFKAIRGEHGMSKNQHGRNADDMVIKVPPGTVVTDDDTKQ VIADLTEHGQRAVIARGGRGGRGNSRFATPANPAPQLSENGEPGKERYIVLELKVLAD VGLVGFPSVGKSTLLSVVSSAKPKIADYHFTTLVPNLGMVETDDGRSFVMADLPGLIE GAHQGVGLGHQFLRHIERTRVIVHVIDMSGLEGRDPYDDYLTINQELSEYNLRLTERP QIIVANKMDMPEAAENLEAFKEKLTDDYPVFPISAVTREGLRELLFEVANQLENTPEF PLYDEEELTQNRVMYTMENEEVPFNITRDPDGVFVLSGDSLERLFKMTDFSRDESVKR FARQMRGMGVDEALRERGAKDGDIIRLLEFEFEFID*" gene complement(2718259..2719545) /gene="obgE" /locus_tag="BSU_27920" /old_locus_tag="BSU27920" CDS complement(2719579..2720157) /gene="spo0B" /locus_tag="BSU_27930" /old_locus_tag="BSU27930" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:9443976, 9477965, 9726997, 9809070, 10997904, 16788205, 27679485" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9443976, 9477965, 9726997, 9809070, 10997904, 16788205, 27679485; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="sporulation initiation phosphotransferase" /protein_id="NP_390671.1" /db_xref="EnsemblGenomes-Gn:BSU27930" /db_xref="EnsemblGenomes-Tr:CAB14753" /db_xref="GOA:P06535" /db_xref="InterPro:IPR016120" /db_xref="InterPro:IPR016122" /db_xref="InterPro:IPR037100" /db_xref="PDB:1F51" /db_xref="PDB:1IXM" /db_xref="PDB:2FTK" /db_xref="SubtiList:BG10336" /db_xref="UniProtKB/Swiss-Prot:P06535" /translation="MKDVSKNQEENISDTALTNELIHLLGHSRHDWMNKLQLIKGNLS LQKYDRVFEMIEEMVIDAKHESKLSNLKTPHLAFDFLTFNWKTHYMTLEYEVLGEIKD LSAYDQKLAKLMRKLFHLFDQAVSRESENHLTVSLQTDHPDRQLILYLDFHGAFADPS AFDDIRQNGYEDVDIMRFEITSHECLIEIGLD*" gene complement(2719579..2720157) /gene="spo0B" /locus_tag="BSU_27930" /old_locus_tag="BSU27930" S_feature complement(2720158..2720223) /Source="Nicolas_S_feature" /locus_tag="new_2854560_2854625_c" /HighExp="Cold, H2O2, G135, Paraq, G180, Oxctl, G150, C30, LPh, dia15" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="0.997, 1" /TUlongSig="SigEF" /TUlongPSig=1 /label="S1058" promotor_-10 complement(2720208..2720227) /Source="Nicolas_upshift_promotors" /id="U2162" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.522477522477522" /psig="0.997002997002997" /xcortree=3176 /SigmaFactorBS="gaaaaaaggaacatgatatttctgggaaaaacaatTGTTTTT CtaacaaagccttcTCTGTTATAATTCATAATACacacttatacagactcctaaataa g" /listShort="S1058, spo0B, obg, yszB, pheA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2720223) /Source="Nicolas_upshifts" /id="U2162" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.522477522477522" /psig="0.997002997002997" /xcortree=3176 /SigmaFactorBS="gaaaaaaggaacatgatatttctgggaaaaacaatTGTTTTT CtaacaaagccttcTCTGTTATAATTCATAATACacacttatacagactcctaaataa g" /listShort="S1058, spo0B, obg, yszB, pheA" /GFF_Attribute="listLong" S_feature complement(2720225..2720442) /Source="Nicolas_S_feature" /locus_tag="new_2854627_2854844_c" /HighExp="Cold, G135, H2O2, Paraq, G180, Oxctl, G150, C30, LPh, HPh" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="SigEF" /TUlongPSig=1 /label="S1059" CDS 2720235..2720357 /locus_tag="BSU_27935" /old_locus_tag="BSU27935" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_009513993.1" /translation="MLEKQLFFPEISCSFFLALVDLQPGRTFYVLLLGEHIQWV*" gene 2720235..2720357 /locus_tag="BSU_27935" /old_locus_tag="BSU27935" promotor_-35 complement(2720241..2720248) /Source="Nicolas_upshift_promotors" /id="U2162" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.522477522477522" /psig="0.997002997002997" /xcortree=3176 /SigmaFactorBS="gaaaaaaggaacatgatatttctgggaaaaacaatTGTTTTT CtaacaaagccttcTCTGTTATAATTCATAATACacacttatacagactcctaaataa g" /listShort="S1058, spo0B, obg, yszB, pheA" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2720478..2720762) /gene="rpmA" /locus_tag="BSU_27940" /old_locus_tag="BSU27940" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:9000630, 9588797, 11399077, 12682299, 14586115, 17981968, 22720735, 24335279, 25388641, 27435445" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9000630, 9588797, 11399077, 12682299, 14586115, 17981968, 22720735, 24335279, 25388641, 27435445; Product type f: factor" /codon_start=1 /transl_table=11 /product="ribosomal protein L27 (BL24)" /protein_id="NP_390672.1" /db_xref="EnsemblGenomes-Gn:BSU27940" /db_xref="EnsemblGenomes-Tr:CAB14754" /db_xref="GOA:P05657" /db_xref="InterPro:IPR001684" /db_xref="InterPro:IPR018261" /db_xref="PDB:3J9W" /db_xref="PDB:5NJT" /db_xref="SubtiList:BG10335" /db_xref="UniProtKB/Swiss-Prot:P05657" /translation="MLRLDLQFFASKKGVGSTKNGRDSEAKRLGAKRADGQFVTGGSI LYRQRGTKIYPGENVGRGGDDTLFAKIDGTVKFERFGRDRKKVSVYPVAQ*" gene complement(2720478..2720762) /gene="rpmA" /locus_tag="BSU_27940" /old_locus_tag="BSU27940" downshifts complement(2720487) /Source="Nicolas_upshifts" /id="D1431" /incds=0 /nref=212 /ntot=261 /MaxReadThrough="7.39131" /MaxDrop="7.26483" /score="32.4992871" /energy="-12.5" /TU="U2163" /idTUdmin="U2164" /TUdmin=1078 /isTUend="FALSE" CDS complement(2720775..2721113) /gene="rppA" /locus_tag="BSU_27950" /old_locus_tag="BSU27950" /function="16.2: Construct biomass (Anabolism)" /function="16.6: Maintain" /function="16.13: Shape" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 11567142, 22333191, 25388641, 27435445, 28187498; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="ribosomal protein L27 specific N-terminal end cysteine protease" /protein_id="NP_390673.2" /db_xref="EnsemblGenomes-Gn:BSU27950" /db_xref="EnsemblGenomes-Tr:CAB14755" /db_xref="InterPro:IPR007422" /db_xref="InterPro:IPR036764" /db_xref="SubtiList:BG10334" /db_xref="UniProtKB/Swiss-Prot:P26942" /translation="MIQATIRRSHDKGILSFEMTGHANFAEHGQDLVCAGVTAVVFGA VNAVIVLAGFEPLLDIGEDGGYFYFEFPESLDPEARQKAQLLIEGMIVSLETIERDYK DNLRVTTNII*" gene complement(2720775..2721113) /gene="rppA" /locus_tag="BSU_27950" /old_locus_tag="BSU27950" CDS complement(2721116..2721424) /gene="rplU" /locus_tag="BSU_27960" /old_locus_tag="BSU27960" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:8223574, 12682299, 22720735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8223574, 12682299, 22720735; Product type s: structure" /codon_start=1 /transl_table=11 /product="ribosomal protein L21 (BL20)" /protein_id="NP_390674.1" /db_xref="EnsemblGenomes-Gn:BSU27960" /db_xref="EnsemblGenomes-Tr:CAB14756" /db_xref="GOA:P26908" /db_xref="InterPro:IPR001787" /db_xref="InterPro:IPR018258" /db_xref="InterPro:IPR028909" /db_xref="InterPro:IPR036164" /db_xref="PDB:3J3V" /db_xref="PDB:3J3W" /db_xref="PDB:3J9W" /db_xref="PDB:5NJT" /db_xref="SubtiList:BG10333" /db_xref="UniProtKB/Swiss-Prot:P26908" /translation="MYAIIKTGGKQIKVEEGQTVYIEKLAAEAGETVTFEDVLFVGGD NVKVGNPTVEGATVTAKVEKQGRAKKITVFRYKPKKNVHKKQGHRQPYTKVTIEKINA *" gene complement(2721116..2721424) /gene="rplU" /locus_tag="BSU_27960" /old_locus_tag="BSU27960" misc_RNA complement(2721438..2721513) /gene="ldlU" /locus_tag="BSU_misc_RNA_43" /product="ribosomal protein L21 leader mRNA sequence" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 27381917" gene complement(2721438..2721513) /gene="ldlU" /locus_tag="BSU_misc_RNA_43" promotor_-10 complement(2721525..2721544) /Source="Nicolas_upshift_promotors" /id="U2163" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.848151848151848" /psig=1 /xcortree=2655 /SigmaFactorBS="attcttccatggaggaactgcttctgccctactaaaactgAT TGACAAacgccttgtatttTGGTATATTTTTTAATGTTAtggatgtagcaccattgct a" /listShort="NA, rplU, ysxB, rpmA, S1059, S1058, spo0B, obg, yszB, pheA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2721545) /Source="Nicolas_upshifts" /id="U2163" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.848151848151848" /psig=1 /xcortree=2655 /SigmaFactorBS="attcttccatggaggaactgcttctgccctactaaaactgAT TGACAAacgccttgtatttTGGTATATTTTTTAATGTTAtggatgtagcaccattgct a" /listShort="NA, rplU, ysxB, rpmA, S1059, S1058, spo0B, obg, yszB, pheA" /GFF_Attribute="listLong" promotor_-35 complement(2721558..2721565) /Source="Nicolas_upshift_promotors" /id="U2163" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.848151848151848" /psig=1 /xcortree=2655 /SigmaFactorBS="attcttccatggaggaactgcttctgccctactaaaactgAT TGACAAacgccttgtatttTGGTATATTTTTTAATGTTAtggatgtagcaccattgct a" /listShort="NA, rplU, ysxB, rpmA, S1059, S1058, spo0B, obg, yszB, pheA" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2721571..2722437) /gene="spoIVFB" /locus_tag="BSU_27970" /old_locus_tag="BSU27970" /EC_number="3.4.24.-" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:10809718, 11959848, 15087499, 16731018, 16816000, 16818230, 26953342, 29180425" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10809718, 11959848, 15087499, 16731018, 16816000, 16818230, 26953342, 29180425; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="membrane metalloprotease [proteolysis of pro-sigma(K)]" /protein_id="NP_390675.1" /db_xref="EnsemblGenomes-Gn:BSU27970" /db_xref="EnsemblGenomes-Tr:CAB14757" /db_xref="GOA:P26937" /db_xref="InterPro:IPR008915" /db_xref="SubtiList:BG10332" /db_xref="UniProtKB/Swiss-Prot:P26937" /translation="MNKWLDLILKIHVHPFLWIIAALGLLTGHMKALLCLLLIVLIHE LGHAALAVFFSWRIKRVFLLPFGGTVEVEEHGNRPLKEEFAVIIAGPLQHIWLQFAAW MLAEVSVIHQHTFELFTFYNLSILFVNLLPIWPLDGGKLLFLLFSKQLPFQKAHRLNL KTSLCFCLLLGCWVLFVIPLQISAWVLFVFLAVSLFEEYRQRHYIHVRFLLERYYGKN RELEKLLPLTVKAEDKVYHVMAEFKRGCKHPIIIEKSGQKLSQLDENEVLHAYFADKR TNSSMEELLLPY*" gene complement(2721571..2722437) /gene="spoIVFB" /locus_tag="BSU_27970" /old_locus_tag="BSU27970" CDS complement(2722430..2723224) /gene="spoIVFA" /locus_tag="BSU_27980" /old_locus_tag="BSU27980" /function="16.3: Control" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:10809718, 11959848, 15087499, 16731018, 16816000, 16818230, 17824930, 22882546" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10809718, 11959848, 15087499, 16731018, 16816000, 16818230, 17824930, 22882546; Product type r: regulator" /codon_start=1 /transl_table=11 /product="regulator of SpoIVFB (stage IV sporulation)" /protein_id="NP_390676.1" /db_xref="EnsemblGenomes-Gn:BSU27980" /db_xref="EnsemblGenomes-Tr:CAB14758" /db_xref="GOA:P26936" /db_xref="InterPro:IPR011055" /db_xref="InterPro:IPR016047" /db_xref="SubtiList:BG10331" /db_xref="UniProtKB/Swiss-Prot:P26936" /translation="MSHRADEIRKRLEKRRKQLSGSKRFSTQTVSEKQKPPSWVMVTD QEKHGTLPVYEDNMPTFNGKHPLVKTDSIILKCLLSACLVLVSAIAYKTNIGPVSQIK PAVAKTFETEFQFASASHWFETKFGNPLAFLAPEHKNKEQQIEVGKDLIAPASGKVQQ DFQDNGEGIKVETSSDKIDSVKEGYVVEVSKDSQTGLTVKVQHADNTYSIYGELKDVD VALYDFVDKGKKLGSIKLDDHNKGVYYFAMKDGDKFIDPIQVISFE*" gene complement(2722430..2723224) /gene="spoIVFA" /locus_tag="BSU_27980" /old_locus_tag="BSU27980" downshifts 2723227 /Source="Nicolas_upshifts" /id="D1432" /incds=0 /nref=1 /ntot=7 /MaxReadThrough="1.00279" /MaxDrop="2.6024" /score="-6.66807377" /energy="-6.9" /TU="NA" /idTUdmin="U2165" /TUdmin="-131" /isTUend="FALSE" promotor_no_box 2723233..2723333 /Source="Nicolas_upshift_promotors" /id="U2165" /multdbtbs="-" /comp="M21" /sig="Sig-" /pcomp="0.536463536463537" /psig="0.242757242757243" /xcortree=281 /SigmaFactorBS="tcctttgcattcgttgggtttgtacatcatatgtcttgtcca tggcaaatattcggtttagtcaagaacaaagcaggcaaaaacaaaaaaaacctgacac a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_no_box" promotor_-10 complement(2723248..2723266) /Source="Nicolas_upshift_promotors" /id="U2164" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=982 /SigmaFactorBS="tttgtttttgcctgctttgttcttgactaaacCGAATAtttg ccatggacaagACATATGATGTACAAACCCaacgaatgcaaaggatgatggcaatgag t" /listShort="spoIVFA, spoIVFB" /listLong="NA, rplU, ysxB, rpmA, S1059, S1058, spo0B, obg, yszB, pheA" /label="promotor_-10" upshifts complement(2723259) /Source="Nicolas_upshifts" /id="U2164" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=982 /SigmaFactorBS="tttgtttttgcctgctttgttcttgactaaacCGAATAtttg ccatggacaagACATATGATGTACAAACCCaacgaatgcaaaggatgatggcaatgag t" /listShort="spoIVFA, spoIVFB" /listLong="NA, rplU, ysxB, rpmA, S1059, S1058, spo0B, obg, yszB, pheA" promotor_-35 complement(2723282..2723287) /Source="Nicolas_upshift_promotors" /id="U2164" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=982 /SigmaFactorBS="tttgtttttgcctgctttgttcttgactaaacCGAATAtttg ccatggacaagACATATGATGTACAAACCCaacgaatgcaaaggatgatggcaatgag t" /listShort="spoIVFA, spoIVFB" /listLong="NA, rplU, ysxB, rpmA, S1059, S1058, spo0B, obg, yszB, pheA" /label="promotor_-35" upshifts 2723293 /Source="Nicolas_upshifts" /id="U2165" /multdbtbs="-" /comp="M21" /sig="Sig-" /pcomp="0.536463536463537" /psig="0.242757242757243" /xcortree=281 /SigmaFactorBS="tcctttgcattcgttgggtttgtacatcatatgtcttgtcca tggcaaatattcggtttagtcaagaacaaagcaggcaaaaacaaaaaaaacctgacac a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" downshifts 2723336 /Source="Nicolas_upshifts" /id="D1433" /incds=0 /nref=2 /ntot=27 /MaxReadThrough="1.68429" /MaxDrop="7.01891" /score="-6.66807377" /energy="-6.9" /TU="U2165" /idTUdmin="U2165" /TUdmin="-22" /isTUend="TRUE" downshifts complement(2723371) /Source="Nicolas_upshifts" /id="D1434" /incds=0 /nref=236 /ntot=262 /MaxReadThrough="2.68001" /MaxDrop="5.80551" /score="40.3102023" /energy="-12.6" /TU="U2166" /idTUdmin="U2167" /TUdmin="-3" /isTUend="TRUE" CDS complement(2723374..2724180) /gene="minD" /locus_tag="BSU_27990" /old_locus_tag="BSU27990" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:11886553, 12426398, 12492852, 12492861, 16322744, 16885474, 17513368, 19019154, 28674273" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11886553, 12426398, 12492852, 12492861, 16322744, 16885474, 17513368, 19019154, 28674273; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="ATPase activator of MinC" /protein_id="NP_390677.1" /db_xref="EnsemblGenomes-Gn:BSU27990" /db_xref="EnsemblGenomes-Tr:CAB14759" /db_xref="GOA:Q01464" /db_xref="InterPro:IPR002586" /db_xref="InterPro:IPR010223" /db_xref="InterPro:IPR025501" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG10330" /db_xref="UniProtKB/Swiss-Prot:Q01464" /translation="MGEAIVITSGKGGVGKTTTSANLGTALAILGKRVCLVDTDIGLR NLDVVMGLENRIIYDLVDVVEGRCKMHQALVKDKRFDDLLYLMPAAQTSDKTAVAPEQ IKNMVQELKQEFDYVIIDCPAGIEQGYKNAVSGADKAIVVTTPEISAVRDADRIIGLL EQEENIEPPRLVVNRIRNHLMKNGDTMDIDEIVQHLSIDLLGIVADDDEVIKASNHGE PIAMDPKNRASIAYRNIARRILGESVPLQVLEEQNKGMMAKIKSFFGVRS*" gene complement(2723374..2724180) /gene="minD" /locus_tag="BSU_27990" /old_locus_tag="BSU27990" CDS complement(2724182..2724862) /gene="minC" /locus_tag="BSU_28000" /old_locus_tag="BSU28000" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:10411726, 12426398, 12446561, 15317782, 16322744, 17326815, 19141479, 20352045, 22720735, 24366721" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10411726, 12426398, 12446561, 15317782, 16322744, 17326815, 19141479, 20352045, 22720735, 24366721; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="cell-division regulator (septum placement)" /protein_id="NP_390678.1" /db_xref="EnsemblGenomes-Gn:BSU28000" /db_xref="EnsemblGenomes-Tr:CAB14760" /db_xref="GOA:Q01463" /db_xref="InterPro:IPR005526" /db_xref="InterPro:IPR013033" /db_xref="InterPro:IPR036145" /db_xref="PDB:2M4I" /db_xref="SubtiList:BG10329" /db_xref="UniProtKB/Swiss-Prot:Q01463" /translation="MKTKKQQYVTIKGTKNGLTLHLDDACSFDELLDGLQNMLSIEQY TDGKGQKISVHVKLGNRFLYKEQEEQLTELIASKKDLFVHSIDSEVITKKEAQQIREE AEIISVSKIVRSGQVLQVKGDLLLIGDVNPGGTVRAGGNIFVLGSLKGIAHAGFNGNN QAVIAASEMLPTQLRINHVLNRSPDHIQKGNEMECAYLDTDGNMVIERLQHLAHLRPD LTRLEGGM*" gene complement(2724182..2724862) /gene="minC" /locus_tag="BSU_28000" /old_locus_tag="BSU28000" CDS complement(2724915..2725433) /gene="mreD" /locus_tag="BSU_28010" /old_locus_tag="BSU28010" /function="16.2: Construct biomass (Anabolism)" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:15849754, 16101995, 16850406, 18156271" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15849754, 16101995, 16850406, 18156271; Product type s: structure" /codon_start=1 /transl_table=11 /product="cell-shape determining protein" /protein_id="NP_390679.1" /db_xref="EnsemblGenomes-Gn:BSU28010" /db_xref="EnsemblGenomes-Tr:CAB14761" /db_xref="GOA:Q01467" /db_xref="InterPro:IPR007227" /db_xref="SubtiList:BG10328" /db_xref="UniProtKB/Swiss-Prot:Q01467" /translation="MKRFLLPFVMMLVFSAESIFTDLVHFPFVTDDQVLAPRFLMLVL IFMSAFINQKHAMIYGFIFGFLYDMNYTSLLGVYMFGFAGLCYLASKAFKVLHTNAFV VILIAVLAVCLLEFYVFGIQSLIHKDIMTFNGFVLDRFIPTILLNIAAALILVLPFRL FFMSLKKELRDE*" gene complement(2724915..2725433) /gene="mreD" /locus_tag="BSU_28010" /old_locus_tag="BSU28010" CDS complement(2725430..2726302) /gene="mreC" /locus_tag="BSU_28020" /old_locus_tag="BSU28020" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:15849754, 16101995, 16850406, 17427287, 20623345" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15849754, 16101995, 16850406, 17427287, 20623345; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="cell-shape determining protein" /protein_id="NP_390680.2" /db_xref="EnsemblGenomes-Gn:BSU28020" /db_xref="EnsemblGenomes-Tr:CAB14762" /db_xref="GOA:Q01466" /db_xref="InterPro:IPR007221" /db_xref="SubtiList:BG10327" /db_xref="UniProtKB/Swiss-Prot:Q01466" /translation="MPNKRLMLLLLCIIILVAMIGFSLKGGRNTTWPEKVIGDTTGVF QNIFHTPAEFFAGIFENINDLKNTYKENERLREKLDGQTQYEAKLQELEEENKSLRDE LGHVKSIKDYKPILATVIARSPDNWAKQVTINKGTQQNVAKDMAVTNEKGALIGKIKS SGLNNFTSAVQLLSDTDRNNRVATKISGKKGSKGYGLIEGYDKEKKRLKMTIIERKDK QDVKKGDLIETSGTGGVFPEGLTIGEVTDIESDSYGLTKVAYVKPAADLTDLNNVIVV NRDVPTVDTEEEGS*" gene complement(2725430..2726302) /gene="mreC" /locus_tag="BSU_28020" /old_locus_tag="BSU28020" CDS complement(2726333..2727346) /gene="mreB" /locus_tag="BSU_28030" /old_locus_tag="BSU28030" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:14588250, 15745453, 15922599, 16322744, 16885474, 17064365, 17513368, 22166997, 24550515, 27376153, 28589952" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 14588250, 15745453, 15922599, 16322744, 16885474, 17064365, 17513368, 22166997, 24550515, 27376153, 28589952; Product type cp : cell process" /codon_start=1 /transl_table=11 /product="cell-shape determining protein" /protein_id="NP_390681.2" /db_xref="EnsemblGenomes-Gn:BSU28030" /db_xref="EnsemblGenomes-Tr:CAB14763" /db_xref="GOA:Q01465" /db_xref="InterPro:IPR004753" /db_xref="SubtiList:BG10326" /db_xref="UniProtKB/Swiss-Prot:Q01465" /translation="MFGIGARDLGIDLGTANTLVFVKGKGIVVREPSVVALQTDTKSI VAVGNDAKNMIGRTPGNVVALRPMKDGVIADYETTATMMKYYINQAIKNKGMFARKPY VMVCVPSGITAVEERAVIDATRQAGARDAYPIEEPFAAAIGANLPVWEPTGSMVVDIG GGTTEVAIISLGGIVTSQSIRVAGDEMDDAIINYIRKTYNLMIGDRTAEAIKMEIGSA EAPEESDNMEIRGRDLLTGLPKTIEITGKEISNALRDTVSTIVEAVKSTLEKTPPELA ADIMDRGIVLTGGGALLRNLDKVISEETKMPVLIAEDPLDCVAIGTGKALEHIHLFKG KTR*" gene complement(2726333..2727346) /gene="mreB" /locus_tag="BSU_28030" /old_locus_tag="BSU28030" upshifts complement(2727387) /Source="Nicolas_upshifts" /id="U2166" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.380619380619381" /psig="0.897102897102897" /xcortree=2535 /SigmaFactorBS="atatttgtaacactttttttttcgtcgaatTAAGCTATAATA GAGTTTAtgagtttttccctttagggtatttttgctttaagaaaggaagatacataca t" /listShort="mreB, mreC, mreD, minC, minD" /GFF_Attribute="listLong" misc_feature complement(2727399..2727417) /Source="Nicolas_upshift_promotors" /id="U2166" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.380619380619381" /psig="0.897102897102897" /xcortree=2535 /SigmaFactorBS="atatttgtaacactttttttttcgtcgaatTAAGCTATAATA GAGTTTAtgagtttttccctttagggtatttttgctttaagaaaggaagatacataca t" /listShort="mreB, mreC, mreD, minC, minD" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" CDS complement(2727438..2728133) /gene="ysxA" /locus_tag="BSU_28040" /old_locus_tag="BSU28040" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 10652786, 17434969, 18556794; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="conserved nucleotide-related metabolism protein" /protein_id="NP_390682.1" /db_xref="EnsemblGenomes-Gn:BSU28040" /db_xref="EnsemblGenomes-Tr:CAB14764" /db_xref="GOA:Q02170" /db_xref="InterPro:IPR000445" /db_xref="InterPro:IPR001405" /db_xref="InterPro:IPR010994" /db_xref="InterPro:IPR020891" /db_xref="InterPro:IPR025657" /db_xref="SubtiList:BG10325" /db_xref="UniProtKB/Swiss-Prot:Q02170" /translation="MVIHDLPLKLKDFPMKEKPRERLLKVGAENLANHELLAILLRTG TKHESVLDLSNRLLRSFDGLRLLKEASVEELSSIPGIGMVKAIQILAAVELGSRIHKL ANEEHFVIRSPEDGANLVMEDMRFLTQEHFVCLYLNTKNQVIHKRTVFIGSLNSSIVH PREVFKEAFKRSAASFICVHNHPSGDPTPSREDIEVTRRLFECGNLIGIELLDHLVIG DKKFVSLKEKGYL*" gene complement(2727438..2728133) /gene="ysxA" /locus_tag="BSU_28040" /old_locus_tag="BSU28040" CDS complement(2728170..2728739) /gene="maf" /locus_tag="BSU_28050" /old_locus_tag="BSU28050" /EC_number="3.6.1.9" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:10841541, 16216582, 21564336, 24210219" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10841541, 16216582, 21564336, 24210219; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="nucleoside triphosphate pyrophosphatase; septum formation DNA-binding protein (multicopy associated filamentation)" /protein_id="NP_390683.1" /db_xref="EnsemblGenomes-Gn:BSU28050" /db_xref="EnsemblGenomes-Tr:CAB14765" /db_xref="GOA:Q02169" /db_xref="InterPro:IPR003697" /db_xref="InterPro:IPR029001" /db_xref="PDB:1EX2" /db_xref="PDB:1EXC" /db_xref="PDB:4HEB" /db_xref="SubtiList:BG10324" /db_xref="UniProtKB/Swiss-Prot:Q02169" /translation="MTKPLILASQSPRRKELLDLLQLPYSIIVSEVEEKLNRNFSPEE NVQWLAKQKAKAVADLHPHAIVIGADTMVCLDGECLGKPQDQEEAASMLRRLSGRSHS VITAVSIQAENHSETFYDKTEVAFWSLSEEEIWTYIETKEPMDKAGAYGIQGRGALFV KKIDGDYYSVMGLPISKTMRALRHFDIRA*" gene complement(2728170..2728739) /gene="maf" /locus_tag="BSU_28050" /old_locus_tag="BSU28050" promotor_-10 complement(2728591..2728606) /Source="Nicolas_upshift_promotors" /id="U2167" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1656 /SigmaFactorBS="ttattgtcagtgaagtagaagaaaaattaaatCGAAACTTTT caccagaagaaaACGTCCAATGGTTGGCaaaacaaaaagctaaggctgtagctgatct c" /listShort="radC, mreB, mreC, mreD, minC, minD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2728600) /Source="Nicolas_upshifts" /id="U2167" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1656 /SigmaFactorBS="ttattgtcagtgaagtagaagaaaaattaaatCGAAACTTTT caccagaagaaaACGTCCAATGGTTGGCaaaacaaaaagctaaggctgtagctgatct c" /listShort="radC, mreB, mreC, mreD, minC, minD" /GFF_Attribute="listLong" promotor_-35 complement(2728619..2728628) /Source="Nicolas_upshift_promotors" /id="U2167" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1656 /SigmaFactorBS="ttattgtcagtgaagtagaagaaaaattaaatCGAAACTTTT caccagaagaaaACGTCCAATGGTTGGCaaaacaaaaagctaaggctgtagctgatct c" /listShort="radC, mreB, mreC, mreD, minC, minD" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(2728778..2728797) /Source="Nicolas_upshift_promotors" /id="U2168" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.296703296703297" /psig=1 /xcortree=2191 /SigmaFactorBS="ctttttttattttgtcatgaaaaagttatttttctgaAATTG TGacaagcctcgtgaTTTGGTAGGATAAACGAGTAtctttttttcttaagcaaaccct g" /listShort="maf, radC, mreB, mreC, mreD, minC, minD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2728794) /Source="Nicolas_upshifts" /id="U2168" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.296703296703297" /psig=1 /xcortree=2191 /SigmaFactorBS="ctttttttattttgtcatgaaaaagttatttttctgaAATTG TGacaagcctcgtgaTTTGGTAGGATAAACGAGTAtctttttttcttaagcaaaccct g" /listShort="maf, radC, mreB, mreC, mreD, minC, minD" /GFF_Attribute="listLong" promotor_-35 complement(2728811..2728817) /Source="Nicolas_upshift_promotors" /id="U2168" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.296703296703297" /psig=1 /xcortree=2191 /SigmaFactorBS="ctttttttattttgtcatgaaaaagttatttttctgaAATTG TGacaagcctcgtgaTTTGGTAGGATAAACGAGTAtctttttttcttaagcaaaccct g" /listShort="maf, radC, mreB, mreC, mreD, minC, minD" /GFF_Attribute="listLong" /label="promotor_-35" downshifts complement(2728890) /Source="Nicolas_upshifts" /id="D1435" /incds=0 /nref=41 /ntot=100 /MaxReadThrough="1.92542" /MaxDrop="5.77117" /score="8.94061802" /energy="-7.4" /TU="NA" /idTUdmin="U2169" /TUdmin=1 /isTUend="TRUE" CDS complement(2728892..2729890) /gene="spoIIB" /locus_tag="BSU_28060" /old_locus_tag="BSU28060" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:16959571, 17376078, 22720735, 22882546" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16959571, 17376078, 22720735, 22882546; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="spatial and temporal regulator of the dissolution of septal peptidoglycan during engulfment (stage II sporulation)" /protein_id="NP_390684.1" /db_xref="EnsemblGenomes-Gn:BSU28060" /db_xref="EnsemblGenomes-Tr:CAB14766" /db_xref="GOA:P37575" /db_xref="InterPro:IPR007730" /db_xref="InterPro:IPR036680" /db_xref="SubtiList:BG10912" /db_xref="UniProtKB/Swiss-Prot:P37575" /translation="MKKRKNKKNSKAAEKALKVTINGKEETVYEQETPETEANKSMTF SNWEEKRQAEQEVAASQEHPDEDEFNWDSEEDKVFKEDPKVVPPFQKKKTKLYAKGKT GAAKPVKRVAATIAFAAVIGTGLGLFALNISGNKEASAPASLEDSLGSQTAKAGDTSA DKQTSGAEKQAAQTEGTYKTYAVQAGKFSNEKGAETLTEQLTEKGYSAVSLSKDDGYT YVIAGLASEKEVSQQLGQVLIDSDFEAWGGKELSLSIESDMTDSFKETAELAAKAILD EDITKASVEKIEKSLGETKASETGEKKAILQALKELEDPSAEAGWKAQQELLAVVK*" gene complement(2728892..2729890) /gene="spoIIB" /locus_tag="BSU_28060" /old_locus_tag="BSU28060" promotor_-10 complement(2729937..2729956) /Source="Nicolas_upshift_promotors" /id="U2169" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.95104895104895" /psig="0.999000999001" /xcortree=443 /SigmaFactorBS="aacgttttttggacaaggcgacaaaagtctTGTTCTTTtttt ctttgccTGTGCTAAAGTGTGTAGCATgaaaagccgacaagaacggtcaagcaaatga a" /listShort="spoIIB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2729945) /Source="Nicolas_upshifts" /id="U2169" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.95104895104895" /psig="0.999000999001" /xcortree=443 /SigmaFactorBS="aacgttttttggacaaggcgacaaaagtctTGTTCTTTtttt ctttgccTGTGCTAAAGTGTGTAGCATgaaaagccgacaagaacggtcaagcaaatga a" /listShort="spoIIB" /GFF_Attribute="listLong" promotor_-35 complement(2729968..2729975) /Source="Nicolas_upshift_promotors" /id="U2169" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.95104895104895" /psig="0.999000999001" /xcortree=443 /SigmaFactorBS="aacgttttttggacaaggcgacaaaagtctTGTTCTTTtttt ctttgccTGTGCTAAAGTGTGTAGCATgaaaagccgacaagaacggtcaagcaaatga a" /listShort="spoIIB" /GFF_Attribute="listLong" /label="promotor_-35" downshifts complement(2730013) /Source="Nicolas_upshifts" /id="D1436" /incds=0 /nref=1 /ntot=56 /MaxReadThrough="3.18314" /MaxDrop="2.89774" /score="11.209969" /energy="-7.6" /TU="U2170" /idTUdmin="U2170" /TUdmin="-440" /isTUend="FALSE" CDS complement(2730024..2730770) /gene="comC" /locus_tag="BSU_28070" /old_locus_tag="BSU28070" /EC_number="3.4.23.43" /function="16.6: Maintain" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:2553669, 9723928, 15849754, 16751195, 16850406, 16751195" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 2553669, 9723928, 15849754, 16751195, 16850406, 16751195; Product type cp : cell process" /codon_start=1 /transl_table=11 /product="membrane prepilin peptidase" /protein_id="NP_390685.2" /db_xref="EnsemblGenomes-Gn:BSU28070" /db_xref="EnsemblGenomes-Tr:CAB14767" /db_xref="GOA:P15378" /db_xref="InterPro:IPR000045" /db_xref="InterPro:IPR010627" /db_xref="SubtiList:BG10323" /db_xref="UniProtKB/Swiss-Prot:P15378" /translation="MLSILFIFGLILGSFYYTAGCRIPLHLSIIAPRSSCPFCRRTLT PAELIPILSFLFQKGKCKSCGHRISFMYPAAELVTACLFAAAGIRFGISLELFPAVVF ISLLIIVAVTDIHFMLIPNRILIFFLPFLAAARLISPLDSWYAGLLGAAAGFLFLAVI AAITHGGVGGGDIKLFAVIGFVLGVKMLAAAFFFSVLIGALYGAAAVLTGRLAKRQPL PFAPAIAAGSILAYLYGDSIISFYIKMALG*" gene complement(2730024..2730770) /gene="comC" /locus_tag="BSU_28070" /old_locus_tag="BSU28070" promotor_-10 complement(2730798..2730817) /Source="Nicolas_upshift_promotors" /id="U2170" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.675324675324675" /psig="0.99000999000999" /xcortree=2963 /SigmaFactorBS="tttcatgtgtaaaattgaatattcccAATTGGAGctcaggat gtccatTTTGCTACAATCCATACCAGaactcaatgagtaaaggtgtgttgtctatgct a" /listShort="comC, spoIIB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2730805) /Source="Nicolas_upshifts" /id="U2170" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.675324675324675" /psig="0.99000999000999" /xcortree=2963 /SigmaFactorBS="tttcatgtgtaaaattgaatattcccAATTGGAGctcaggat gtccatTTTGCTACAATCCATACCAGaactcaatgagtaaaggtgtgttgtctatgct a" /listShort="comC, spoIIB" /GFF_Attribute="listLong" promotor_-35 complement(2730832..2730839) /Source="Nicolas_upshift_promotors" /id="U2170" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.675324675324675" /psig="0.99000999000999" /xcortree=2963 /SigmaFactorBS="tttcatgtgtaaaattgaatattcccAATTGGAGctcaggat gtccatTTTGCTACAATCCATACCAGaactcaatgagtaaaggtgtgttgtctatgct a" /listShort="comC, spoIIB" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2730910..2732202) /gene="folC" /locus_tag="BSU_28080" /old_locus_tag="BSU28080" /EC_number="6.3.2.17" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 2105929, 2985605, 3040739, 6994831, 9098041, 15705579, 22720735, 26443588; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="folyl-polyglutamate synthase" /protein_id="NP_390686.1" /db_xref="EnsemblGenomes-Gn:BSU28080" /db_xref="EnsemblGenomes-Tr:CAB14768" /db_xref="GOA:Q05865" /db_xref="InterPro:IPR001645" /db_xref="InterPro:IPR004101" /db_xref="InterPro:IPR013221" /db_xref="InterPro:IPR018109" /db_xref="InterPro:IPR036565" /db_xref="InterPro:IPR036615" /db_xref="SubtiList:BG10322" /db_xref="UniProtKB/Swiss-Prot:Q05865" /translation="MFTAYQDARSWIHGRLKFGVKPGLGRMKQLMARLGHPEKKIRAF HVAGTNGKGSTVAFIRSMLQEAGYTVGTFTSPYIITFNERISVNGIPISDEEWTALVN QMKPHVEALDQTEYGQPTEFEIMTACAFLYFAEFHKVDFVIFETGLGGRFDSTNVVEP LLTVITSIGHDHMNILGNTIEEIAGEKAGIIKEGIPIVTAVTQPEALQVIRHEAERHA APFQSLHDACVIFNEEALPAGEQFSFKTEEKCYEDIRTSLIGTHQRQNAALSILAAEW LNKENIAHISDEALRSGLVKAAWPGRLELVQEHPPVYLDGAHNEEGVEKLAETMKQRF ANSRISVVFSALKDKPYQNMIKRLETIAHAIHFASFDFPRASLAKDLYDASEISNKSW SEDPDDVIKFIESKKGSNEIVLITGSLYFISDIRKRLK*" gene complement(2730910..2732202) /gene="folC" /locus_tag="BSU_28080" /old_locus_tag="BSU28080" downshifts complement(2730915) /Source="Nicolas_upshifts" /id="D1437" /incds=0 /nref=1 /ntot=121 /MaxReadThrough="1.66565" /MaxDrop="3.18428" /score="24.7086033" /energy="-14.3" /TU="NA" /idTUdmin="U2171" /TUdmin=0 /isTUend="TRUE" S_feature complement(2732203..2732261) /Source="Nicolas_S_feature" /locus_tag="new_2866605_2866663_c" /HighExp="S0, LBGexp, G150, MG 45, G135, G180, Gly, Oxctl, M0t45, LBGtran" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="SigEF" /TUlongPSig=1 /label="S1060" CDS complement(2732262..2734904) /gene="valS" /locus_tag="BSU_28090" /old_locus_tag="BSU28090" /EC_number="6.1.1.9" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:9098041, 11114335, 25310979" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9098041, 11114335, 25310979; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="valyl-tRNA synthetase" /protein_id="NP_390687.2" /db_xref="EnsemblGenomes-Gn:BSU28090" /db_xref="EnsemblGenomes-Tr:CAB14769" /db_xref="GOA:Q05873" /db_xref="InterPro:IPR001412" /db_xref="InterPro:IPR002300" /db_xref="InterPro:IPR002303" /db_xref="InterPro:IPR009008" /db_xref="InterPro:IPR009080" /db_xref="InterPro:IPR010978" /db_xref="InterPro:IPR013155" /db_xref="InterPro:IPR014729" /db_xref="InterPro:IPR019499" /db_xref="InterPro:IPR033705" /db_xref="InterPro:IPR037118" /db_xref="SubtiList:BG10321" /db_xref="UniProtKB/Swiss-Prot:Q05873" /translation="METNEQTMPTKYDPAAVEKDRYDFWLKGKFFEAGSDQTKEPYSV VIPPPNVTGRLHLGHAWDTTLQDIVTRMKRMQGYDVLWLPGMDHAGIATQAKVEAKLR EEGKSRYDLGREKFLEETWKWKEEYADFIRSQWAKLGLGLDYSRERFTLDEGLSKAVR EVFVKLYEKGLIYRGEYIINWDPATKTALSDIEVIYKDVQGAFYHMSYPLADGSGSIE IATTRPETMLGDTAVAVHPEDERYKHLIGKTVILPIVNREIPIVGDDYVDMEFGSGAV KITPAHDPNDFELGNRHNLERILVMNEDGTMNENALQYQGMDRFECRKKLVKDLQEAG VLFKIEDHMHSVGHSERSGAVVEPYLSTQWFVRMQPLADAAIELQKKEEKVNFVPDRF EKTYLHWMENIRDWCISRQLWWGHRIPAWYHKETGELYVGLEAPEDSENWEQDTDVLD TWFSSALWPFSTMGWPDVTAEDFKRYYPTDVLVTGYDIIFFWVSRMIFQGIEFTGERP FKDVLIHGLIRDEQGRKMSKSLGNGVDPMDVIDKYGADSLRYFLATGSSPGQDLRFSY EKVESTWNFANKIWNASRFALMNMDGMTYDELDLSGEKSVADKWILTRLNETIEHVTQ LADRYEFGEVGRHLYNFIWDDFCDWYIEMAKLPLYGEDEAAKKTTRSILAYVLDQTMR LLHPFMPFLTEEIWQHLPHQGESITVSQWPAVVPEHTDTEAAADMKLLVELIRSVRNI RSEVNTPMSKQVELYIKTSTDEIASRLEANRSYVERFTNPSVLKIGTDIEAVDKAMTA VVSGAEVILPLEGLINIDEEIARLQKEFDKLTKEVERVQKKLGNEGFMKKAPAHVIDE EREKEKDYVAKRDAVQKRMAELKG*" gene complement(2732262..2734904) /gene="valS" /locus_tag="BSU_28090" /old_locus_tag="BSU28090" S_feature complement(2734905..2734963) /Source="Nicolas_S_feature" /locus_tag="new_2869307_2869365_c" /HighExp="G150, G180, LBGexp, Oxctl, G135, dia0, HPh, Lbexp, Paraq, MG 60" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, Sig-, SigEF" /TUshortPSig="1, 0.012, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S1061" misc_RNA complement(2734964..2735186) /gene="tboV" /locus_tag="BSU_misc_RNA_44" /product="T-box riboswitch specific of valine tRNA" /experiment="publication(s) with functional evidences, PMID:1317842, 9098041, 12165569, 12547201" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1317842, 9098041, 12165569, 12547201; Product type n: RNA" /function="16.3: Control" gene complement(2734964..2735186) /gene="tboV" /locus_tag="BSU_misc_RNA_44" downshifts complement(2735007) /Source="Nicolas_upshifts" /id="D1438" /incds=0 /nref=9 /ntot=27 /MaxReadThrough="6.76593" /MaxDrop="4.53149" /score="23.9897385" /energy="-20" /TU="U2171,U2173,U2176" /idTUdmin="U2176" /TUdmin="-726" /isTUend="FALSE" promotor_-10 complement(2735215..2735234) /Source="Nicolas_upshift_promotors" /id="U2171" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.492507492507492" /psig=1 /xcortree=2387 /SigmaFactorBS="tctgtatagaaagcggtgtttttggaaaagatgATTGACgaa tcaaaaacactTTTACTATAATAAAGAACATaaataatgtatacaatgagctgataaa t" /listShort="NA, S1061, valS, S1060, folC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2735227) /Source="Nicolas_upshifts" /id="U2171" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.492507492507492" /psig=1 /xcortree=2387 /SigmaFactorBS="tctgtatagaaagcggtgtttttggaaaagatgATTGACgaa tcaaaaacactTTTACTATAATAAAGAACATaaataatgtatacaatgagctgataaa t" /listShort="NA, S1061, valS, S1060, folC" /GFF_Attribute="listLong" S_feature complement(2735229..2735337) /Source="Nicolas_S_feature" /locus_tag="new_2869631_2869739_c" /HighExp="S8, S6, S7, S5, B36, LoTm, S4, S3, BT, B60" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="Sig-, SigEF" /TUshortPSig="0.012, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S1062" promotor_-35 complement(2735249..2735254) /Source="Nicolas_upshift_promotors" /id="U2171" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.492507492507492" /psig=1 /xcortree=2387 /SigmaFactorBS="tctgtatagaaagcggtgtttttggaaaagatgATTGACgaa tcaaaaacactTTTACTATAATAAAGAACATaaataatgtatacaatgagctgataaa t" /listShort="NA, S1061, valS, S1060, folC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 2735291..2735300 /Source="Nicolas_upshift_promotors" /id="U2172" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1272 /SigmaFactorBS="tcatcttttccaaaaacaccgctttctatacagatggGCAGG CACCTattgcccaagttTACATATGATGCTTGTAAATgcgtagaggaggatgcaccgt g" /listShort="yszA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2735313..2735332 /Source="Nicolas_upshift_promotors" /id="U2172" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1272 /SigmaFactorBS="tcatcttttccaaaaacaccgctttctatacagatggGCAGG CACCTattgcccaagttTACATATGATGCTTGTAAATgcgtagaggaggatgcaccgt g" /listShort="yszA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2735314 /Source="Nicolas_upshifts" /id="U2172" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1272 /SigmaFactorBS="tcatcttttccaaaaacaccgctttctatacagatggGCAGG CACCTattgcccaagttTACATATGATGCTTGTAAATgcgtagaggaggatgcaccgt g" /listShort="yszA" /GFF_Attribute="listLong" promotor_-10 complement(2735330..2735344) /Source="Nicolas_upshift_promotors" /id="U2173" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.98001998001998" /psig="0.011988011988012" /xcortree=1270 /SigmaFactorBS="gccttacccatggcggcagcgaataagagctgaaacgtttcT TCACggtgcatCCTCCTCTACGCATTtacaagcatcatatgtaaacttgggcaatagg t" /listShort="S1062, NA, S1061, valS" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2735337) /Source="Nicolas_upshifts" /id="U2173" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.98001998001998" /psig="0.011988011988012" /xcortree=1270 /SigmaFactorBS="gccttacccatggcggcagcgaataagagctgaaacgtttcT TCACggtgcatCCTCCTCTACGCATTtacaagcatcatatgtaaacttgggcaatagg t" /listShort="S1062, NA, S1061, valS" /GFF_Attribute="listLong" promotor_-35 complement(2735352..2735356) /Source="Nicolas_upshift_promotors" /id="U2173" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.98001998001998" /psig="0.011988011988012" /xcortree=1270 /SigmaFactorBS="gccttacccatggcggcagcgaataagagctgaaacgtttcT TCACggtgcatCCTCCTCTACGCATTtacaagcatcatatgtaaacttgggcaatagg t" /listShort="S1062, NA, S1061, valS" /GFF_Attribute="listLong" /label="promotor_-35" CDS 2735352..2735543 /gene="yszA" /locus_tag="BSU_28099" /old_locus_tag="BSU28099" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="YP_003097770.1" /db_xref="EnsemblGenomes-Gn:BSU28099" /db_xref="EnsemblGenomes-Tr:CAX52676" /db_xref="GOA:C0H465" /db_xref="UniProtKB/Swiss-Prot:C0H465" /translation="MKKRFSSYSLPPWVRQIRLVSAQVIIPITIFQGIRTIFFPTTFD VLLLAILIFLACALHLEWI*" gene 2735352..2735543 /gene="yszA" /locus_tag="BSU_28099" /old_locus_tag="BSU28099" CDS complement(2735562..2736587) /gene="cotN" /locus_tag="BSU_28100" /old_locus_tag="BSU28100" /function="16.5: Explore" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:16371471, 16390444, 22091839" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16371471, 16390444, 22091839; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="spore coat protein" /protein_id="NP_390688.1" /db_xref="EnsemblGenomes-Gn:BSU28100" /db_xref="EnsemblGenomes-Tr:CAB14770" /db_xref="InterPro:IPR011009" /db_xref="InterPro:IPR014253" /db_xref="SubtiList:BG10347" /db_xref="UniProtKB/Swiss-Prot:P37964" /translation="MEDTQSVLQEYGLTAQFIEPVSPLVWKVYTDYGIFALKKLKEGR GKHFTDHMVAIEEKGFRSFVPVYRTNSGEFFSAGIQYGDIYYLMPWLQFDQEEERDQK HAYLFRETARLHERTAQELKVRRDEIERYYGQTKKKWEQDKIFYEQFVDRAEKEWYLS PFELQAITYFSETISAVNFALERLEDWYESAKEKDVSRVVMNHGSLSIHHFLYNDAGT GYFTNFERASVGPPQNDLLGFYTKMFRGFPKACPECVEWFYGYTKSFPLREAEVSLFL SYMAYPAAMYKVLNGYQTGKRQHEKEECTQLLKAYWQMKNIEPFVMKIHQIEQEKKFQ AENESTS*" gene complement(2735562..2736587) /gene="cotN" /locus_tag="BSU_28100" /old_locus_tag="BSU28100" downshifts complement(2735592) /Source="Nicolas_upshifts" /id="D1439" /incds=0 /nref=23 /ntot=70 /MaxReadThrough="4.44965" /MaxDrop="6.68961" /score="-7.46388093" /energy="-12.1" /TU="U2176" /idTUdmin="U2176" /TUdmin="-1311" /isTUend="FALSE" CDS complement(2736620..2738347) /gene="spoVID" /locus_tag="BSU_28110" /old_locus_tag="BSU28110" /function="16.13: Shape" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:11325931, 16371471, 16950916, 22773792, 23178679" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11325931, 16371471, 16950916, 22773792, 23178679; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="morphogenetic spore protein (stage VI sporulation)" /protein_id="NP_390689.1" /db_xref="EnsemblGenomes-Gn:BSU28110" /db_xref="EnsemblGenomes-Tr:CAB14771" /db_xref="GOA:P37963" /db_xref="InterPro:IPR018392" /db_xref="InterPro:IPR036779" /db_xref="SubtiList:BG10346" /db_xref="UniProtKB/Swiss-Prot:P37963" /translation="MPQNHRLQFSVEESICFQKGQEVSELLSISLDPDIRVQEVNDYV SIIGSLELTGEYNIDQNKHTEEIYTDKRFVEQVRKREDGSAELTHCFPVDITIPKNKV SHLQDVFVFIDAFDYQLTDSRILTIQADLAIEGLLDDTQDKEPEIPLYEAPAAFREEE LSEPPAHSVVEEPGASSAEEAVLQHEPPAEPPELFISKAGLREELETEKAESEPPESV ASEPEAREDVKEEEESEELAVPETEVRAESETEESEPEPDPSEIEIQEIVKAKKETAE PAAAIADVREEADSPAETELREHVGAEESPALEAELHSETVIAKEKEETTVSPNHEYA LRQEAQNEEAAQSDQADPALCQEEAEPDEALESVSEAALSIEDSRETASAVYMENDNA DLHFHFNQKTSSEEASQEELPEPAYRTFLPEQEEEDSFYSAPKLLEEEEQEEESFEIE VRKTPSAEEPKEETPFQSFQLPESSETERKETDAVPRVAPAAETKEPQTKESDNSLYL TKLFTKEADEFSRMKICIVQQEDTIERLCERYEITSQQLIRMNSLALDDELKAGQILY IPQYKNSHA*" gene complement(2736620..2738347) /gene="spoVID" /locus_tag="BSU_28110" /old_locus_tag="BSU28110" promotor_-35 2737949..2737952 /Source="Nicolas_upshift_promotors" /id="U2174" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.456543456543457" /psig="0.684315684315684" /xcortree=691 /SigmaFactorBS="ggctctttgtcttgcgtatcgtccaaaagcccttcGATCgct aaatcagcttgaATTGTTAAAATGCGCGAATCcgtcaattgatagtcaaatgcgtcaa t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2737968..2737987 /Source="Nicolas_upshift_promotors" /id="U2174" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.456543456543457" /psig="0.684315684315684" /xcortree=691 /SigmaFactorBS="ggctctttgtcttgcgtatcgtccaaaagcccttcGATCgct aaatcagcttgaATTGTTAAAATGCGCGAATCcgtcaattgatagtcaaatgcgtcaa t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2737974 /Source="Nicolas_upshifts" /id="U2174" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.456543456543457" /psig="0.684315684315684" /xcortree=691 /SigmaFactorBS="ggctctttgtcttgcgtatcgtccaaaagcccttcGATCgct aaatcagcttgaATTGTTAAAATGCGCGAATCcgtcaattgatagtcaaatgcgtcaa t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 2738343..2738347 /Source="Nicolas_upshift_promotors" /id="U2175" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp=1 /psig=0 /xcortree=699 /SigmaFactorBS="tcttctacagaaaattgcaatcgatgattttgcGGCAAgttc atatCCTCCTTTCATCTAAtccttaaaattagatgtcactaaaggtgtatgtatgaac t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2738356..2738370 /Source="Nicolas_upshift_promotors" /id="U2175" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp=1 /psig=0 /xcortree=699 /SigmaFactorBS="tcttctacagaaaattgcaatcgatgattttgcGGCAAgttc atatCCTCCTTTCATCTAAtccttaaaattagatgtcactaaaggtgtatgtatgaac t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2738370 /Source="Nicolas_upshifts" /id="U2175" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp=1 /psig=0 /xcortree=699 /SigmaFactorBS="tcttctacagaaaattgcaatcgatgattttgcGGCAAgttc atatCCTCCTTTCATCTAAtccttaaaattagatgtcactaaaggtgtatgtatgaac t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 complement(2738385..2738403) /Source="Nicolas_upshift_promotors" /id="U2176" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1091 /SigmaFactorBS="caaggactccttgtgccggttttttcgtgctctcccaCTCAT AttttctccagttcatACATACACCTTTAGTGACAtctaattttaaggattagatgaa a" /listShort="spoVID, ysxE, S1062, NA, S1061, valS" /listLong="S1060, folC" /label="promotor_-10" upshifts complement(2738401) /Source="Nicolas_upshifts" /id="U2176" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1091 /SigmaFactorBS="caaggactccttgtgccggttttttcgtgctctcccaCTCAT AttttctccagttcatACATACACCTTTAGTGACAtctaattttaaggattagatgaa a" /listShort="spoVID, ysxE, S1062, NA, S1061, valS" /listLong="S1060, folC" promotor_-35 complement(2738419..2738424) /Source="Nicolas_upshift_promotors" /id="U2176" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1091 /SigmaFactorBS="caaggactccttgtgccggttttttcgtgctctcccaCTCAT AttttctccagttcatACATACACCTTTAGTGACAtctaattttaaggattagatgaa a" /listShort="spoVID, ysxE, S1062, NA, S1061, valS" /listLong="S1060, folC" /label="promotor_-35" CDS complement(2738478..2739770) /gene="hemL" /locus_tag="BSU_28120" /old_locus_tag="BSU28120" /EC_number="5.4.3.8" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:1672867, 12029044, 15802251, 16682782, 20946885, 27303897" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1672867, 12029044, 15802251, 16682782, 20946885, 27303897; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="glutamate-1-semialdehyde 2,1-aminomutase" /protein_id="NP_390690.1" /db_xref="EnsemblGenomes-Gn:BSU28120" /db_xref="EnsemblGenomes-Tr:CAB14772" /db_xref="GOA:P30949" /db_xref="InterPro:IPR004639" /db_xref="InterPro:IPR005814" /db_xref="InterPro:IPR015421" /db_xref="InterPro:IPR015422" /db_xref="InterPro:IPR015424" /db_xref="PDB:3BS8" /db_xref="SubtiList:BG10345" /db_xref="UniProtKB/Swiss-Prot:P30949" /translation="MRSYEKSKTAFKEAQKLMPGGVNSPVRAFKSVDMDPIFMERGKG SKIFDIDGNEYIDYVLSWGPLILGHTNDRVVESLKKVAEYGTSFGAPTEVENELAKLV IDRVPSVEIVRMVSSGTEATMSALRLARGYTGRNKILKFEGCYHGHGDSLLIKAGSGV ATLGLPDSPGVPEGIAKNTITVPYNDLESVKLAFQQFGEDIAGVIVEPVAGNMGVVPP QEGFLQGLRDITEQYGSLLIFDEVMTGFRVDYNCAQGYFGVTPDLTCLGKVIGGGLPV GAYGGKAEIMEQIAPSGPIYQAGTLSGNPLAMTAGLETLKQLTPESYKNFIKKGDRLE EGISKTAGAHGIPHTFNRAGSMIGFFFTNEPVINYETAKSSDLKLFASYYKGMANEGV FLPPSQFEGLFLSTAHTDEDIENTIQAAEKVFAEISRR*" gene complement(2738478..2739770) /gene="hemL" /locus_tag="BSU_28120" /old_locus_tag="BSU28120" downshifts complement(2738495) /Source="Nicolas_upshifts" /id="D1440" /incds=0 /nref=144 /ntot=397 /MaxReadThrough="3.40168" /MaxDrop="7.29251" /score="3.77738386" /energy="-10.6" /TU="NA" /idTUdmin="U2177" /TUdmin="-5" /isTUend="TRUE" CDS complement(2739800..2740774) /gene="hemB" /locus_tag="BSU_28130" /old_locus_tag="BSU28130" /EC_number="4.2.1.24" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:2110138, 12029044, 15802251, 20823524, 24598743" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 2110138, 12029044, 15802251, 20823524, 24598743; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="delta-aminolevulinic acid dehydratase (porphobilinogen synthase)" /protein_id="NP_390691.1" /db_xref="EnsemblGenomes-Gn:BSU28130" /db_xref="EnsemblGenomes-Tr:CAB14773" /db_xref="GOA:P30950" /db_xref="InterPro:IPR001731" /db_xref="InterPro:IPR013785" /db_xref="InterPro:IPR030656" /db_xref="SubtiList:BG10344" /db_xref="UniProtKB/Swiss-Prot:P30950" /translation="MSQSFNRHRRLRTSKAMREMVKETRLHPSDFIYPIFVVEGLEGK KAVPSMPDVHHVSLDLLKDEVAELVKLGIQSVIVFGIPEEKDDCGTQAYHDHGIVQKA ITEIKEHFPEMVVVADTCLCEYTDHGHCGLVKDGVILNDESLELLAQTAVSQAKAGAD IIAPSNMMDGFVTVIREALDKEGFVNIPIMSYAVKYSSEFYGPFRDAANSTPQFGDRK TYQMDPANRMEALREAQSDVEEGADFLIVKPSLSYMDIMRDVKNEFTLPLVAYNVSGE YSMVKAAAQNGWIKEKEIVLEILTSMKRAGADLIITYHAKDAAKWLAE*" gene complement(2739800..2740774) /gene="hemB" /locus_tag="BSU_28130" /old_locus_tag="BSU28130" CDS complement(2740771..2741559) /gene="hemD" /locus_tag="BSU_28140" /old_locus_tag="BSU28140" /EC_number="4.2.1.75" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:1672867, 2110138, 7628476, 12029044, 12196144, 15802251" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1672867, 2110138, 7628476, 12029044, 12196144, 15802251; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="uroporphyrinogen III cosynthase" /protein_id="NP_390692.1" /db_xref="EnsemblGenomes-Gn:BSU28140" /db_xref="EnsemblGenomes-Tr:CAB14774" /db_xref="GOA:P21248" /db_xref="InterPro:IPR003754" /db_xref="InterPro:IPR036108" /db_xref="SubtiList:BG10343" /db_xref="UniProtKB/Swiss-Prot:P21248" /translation="MENDFPLKGKTVLVTRNKAQAASFQQKVEALGGKAVLTSLITFR RALPNDVAEQVREDLAAPGWLVFTSVNGADFFFSYLKENQLILPAHKKIAAVGEKTAR RLKMHNVSVDVMPQEYIAEQLADALKQHAEPGETITVMKGNLSRDVIKQELVPLGFEV KEWVLYETIPDEEGIEALKDAAGQYSFDYVTFTSSSTVHTFMHVLGEELKKWKANGTA CISIGPLTNDALLTYGITSHTPDTFTIDGMLELMCSMSREEERI*" gene complement(2740771..2741559) /gene="hemD" /locus_tag="BSU_28140" /old_locus_tag="BSU28140" CDS complement(2741549..2742493) /gene="hemC" /locus_tag="BSU_28150" /old_locus_tag="BSU28150" /EC_number="2.5.1.61" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:2110138, 9058548, 12029044, 15802251, 23908040, 24598743" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 2110138, 9058548, 12029044, 15802251, 23908040, 24598743; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="porphobilinogen deaminase (hydroxymethylbilane synthase)" /protein_id="NP_390693.1" /db_xref="EnsemblGenomes-Gn:BSU28150" /db_xref="EnsemblGenomes-Tr:CAB14775" /db_xref="GOA:P16616" /db_xref="InterPro:IPR000860" /db_xref="InterPro:IPR022417" /db_xref="InterPro:IPR022418" /db_xref="InterPro:IPR022419" /db_xref="InterPro:IPR036803" /db_xref="SubtiList:BG10342" /db_xref="UniProtKB/Swiss-Prot:P16616" /translation="MMRTIKVGSRRSKLAMTQTKWVIQKLKEINPSFAFEIKEIVTKG DRIVDVTLSKVGGKGLFVKEIEQALLNEEIDMAVHSMKDMPAVLPEGLVIGCIPERED PRDALISKNRVKLSEMKKGAVIGTSSLRRSAQLLIERPDLTIKWIRGNIDTRLQKLET EDYDAIILAAAGLSRMGWKQDVVTEFLEPERCLPAVGQGALAIECRESDEELLALFSQ FTDEYTKRTVLAERAFLNAMEGGCQVPIAGYSVLNGQDEIEMTGLVASPDGKIIFKET VTGNDPEEVGKRCAALMADKGAKDLIDRVKRELDEDGK*" gene complement(2741549..2742493) /gene="hemC" /locus_tag="BSU_28150" /old_locus_tag="BSU28150" CDS complement(2742526..2743356) /gene="hemX" /locus_tag="BSU_28160" /old_locus_tag="BSU28160" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:8012594, 12029044, 15802251, 15849754, 16850406" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8012594, 12029044, 15802251, 15849754, 16850406; Product type f: factor" /codon_start=1 /transl_table=11 /product="negative effector of the concentration of glutamyl-tRNA reductase HemA" /protein_id="NP_390694.2" /db_xref="EnsemblGenomes-Gn:BSU28160" /db_xref="EnsemblGenomes-Tr:CAB14776" /db_xref="GOA:P16645" /db_xref="InterPro:IPR002541" /db_xref="SubtiList:BG10341" /db_xref="UniProtKB/Swiss-Prot:P16645" /translation="MIDTAMARLNEGTIVIYALSVLFYFIDFLQHNRKAGKMAFWLLS IVWTLQTVYLAYFMWVTGRFPVLNVTEALYFYAWVLVTLSLVLTKLLRVDFIVFFTNV IGFSMIAIHTFSPTEQQSAAFSGQLVSELLVIHITMAILSYGAFSLSFVFSVLYMFQY HLLKKKKWGKWLLRIEDLSKLDYMAYVLNVIGVPMLLLSLILGVIWAYVSLETLYWFD AKVLGSFVVLLLYSYYLYIRLIKELQGKVAALWNTACFLVLMINYFLLGSLSQFHWFS *" gene complement(2742526..2743356) /gene="hemX" /locus_tag="BSU_28160" /old_locus_tag="BSU28160" CDS complement(2743364..2744731) /gene="hemA" /locus_tag="BSU_28170" /old_locus_tag="BSU28170" /EC_number="1.2.1.70" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:1536660, 15802251, 1672867, 2490162, 12029044" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1536660, 15802251, 1672867, 2490162, 12029044; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="glutamyl-tRNA reductase" /protein_id="NP_390695.1" /db_xref="EnsemblGenomes-Gn:BSU28170" /db_xref="EnsemblGenomes-Tr:CAB14777" /db_xref="GOA:P16618" /db_xref="InterPro:IPR000343" /db_xref="InterPro:IPR006151" /db_xref="InterPro:IPR015895" /db_xref="InterPro:IPR015896" /db_xref="InterPro:IPR018214" /db_xref="InterPro:IPR036291" /db_xref="InterPro:IPR036343" /db_xref="InterPro:IPR036453" /db_xref="SubtiList:BG10340" /db_xref="UniProtKB/Swiss-Prot:P16618" /translation="MHILVVGVDYKSAPIEIREKVSFQPNELAEAMVQLKEEKSILEN IIVSTCNRTEIYAVVDQLHTGRYYIKKFLADWFQLSKEELSPFLTFYESDAAVEHLFR VACGLDSMVIGETQILGQVRDSFKTAQQEKTIGTIFNELFKQAVTVGKRTHAETDIGS NAVSVSYAAVELAKKIFGNLSSKHILILGAGKMGELAAENLHGQGIGKVTVINRTYLK AKELADRFSGEARSLNQLESALAEADILISSTGASEFVVSKEMMENANKLRKGRPLFM VDIAVPRDLDPALNDLEGVFLYDIDDLEGIVEANMKERRETAEKVELLIEETIVEFKQ WMNTLGVVPVISALREKALAIQSETMDSIERKLPHLSTREKKLLNKHTKSIINQMLRD PILKVKELAADADSEEKLALFMQIFDIEEAAGRQMMKTVESSQKVHSFKKAESKAGFS PLVSE*" gene complement(2743364..2744731) /gene="hemA" /locus_tag="BSU_28170" /old_locus_tag="BSU28170" misc_feature complement(2744795..2744814) /Source="Nicolas_upshift_promotors" /id="U2177" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.932067932067932" /psig="0.999000999001" /xcortree=1604 /SigmaFactorBS="atatagcataagaattttaaaatctgttcacattttgtgaaa gaaacTATGTTATAATTATTATAAAtaatgagttctatgttagaatgattataaatta a" /listShort="hemA, hemX, hemC, hemD, hemB, hemL" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(2744801) /Source="Nicolas_upshifts" /id="U2177" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.932067932067932" /psig="0.999000999001" /xcortree=1604 /SigmaFactorBS="atatagcataagaattttaaaatctgttcacattttgtgaaa gaaacTATGTTATAATTATTATAAAtaatgagttctatgttagaatgattataaatta a" /listShort="hemA, hemX, hemC, hemD, hemB, hemL" /GFF_Attribute="listLong" S_feature complement(2744803..2744892) /Source="Nicolas_S_feature" /locus_tag="new_2879205_2879294_c" /HighExp="dia15, Salt, dia5, Etha, Paraq, H2O2, Diami, Heat, LoTm, S5" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigB, SigGF" /TUshortPSig="0.997, 1, 0.948" /TUlongSig="NA" /TUlongPSig="NA" /label="S1063" misc_feature 2744852..2744871 /Source="Nicolas_upshift_promotors" /id="U2178" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.94105894105894" /psig=1 /xcortree=2409 /SigmaFactorBS="aataattataacatagtttctttcacaaaatgtgaacagatt ttaaaattctTATGCTATATTAGAAAAAGCttcagggaaaagaagcattcctattgac a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 2744860 /Source="Nicolas_upshifts" /id="U2178" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.94105894105894" /psig=1 /xcortree=2409 /SigmaFactorBS="aataattataacatagtttctttcacaaaatgtgaacagatt ttaaaattctTATGCTATATTAGAAAAAGCttcagggaaaagaagcattcctattgac a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 complement(2744889..2744908) /Source="Nicolas_upshift_promotors" /id="U2179" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.693306693306693" /psig="0.997002997002997" /xcortree=1856 /SigmaFactorBS="ccttcttgttttttagagctgatgtGTAGTAAATttctgctg ttTTTGGTATTGTCAATAGGAAtgcttcttttccctgaagctttttctaatatagcat a" /listShort="S1063, hemA, hemX, hemC, hemD, hemB, hemL" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2744892) /Source="Nicolas_upshifts" /id="U2179" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.693306693306693" /psig="0.997002997002997" /xcortree=1856 /SigmaFactorBS="ccttcttgttttttagagctgatgtGTAGTAAATttctgctg ttTTTGGTATTGTCAATAGGAAtgcttcttttccctgaagctttttctaatatagcat a" /listShort="S1063, hemA, hemX, hemC, hemD, hemB, hemL" /GFF_Attribute="listLong" S_feature complement(2744894..2745310) /Source="Nicolas_S_feature" /locus_tag="new_2879296_2879712_c" /HighExp="Etha, S5, Gly, S7, S4, S8, S6, H2O2, dia15, G135" /AntisenseName="ysxD" /AntisenseCor="-1.16761021676615E-2" /AntisenseRegPval="-0.1" /CDS_PredictionProba="NA" /TUshortSig="SigB, SigGF" /TUshortPSig="1, 0.948" /TUlongSig="NA" /TUlongPSig="NA" /label="S1064" promotor_-35 complement(2744919..2744927) /Source="Nicolas_upshift_promotors" /id="U2179" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.693306693306693" /psig="0.997002997002997" /xcortree=1856 /SigmaFactorBS="ccttcttgttttttagagctgatgtGTAGTAAATttctgctg ttTTTGGTATTGTCAATAGGAAtgcttcttttccctgaagctttttctaatatagcat a" /listShort="S1063, hemA, hemX, hemC, hemD, hemB, hemL" /GFF_Attribute="listLong" /label="promotor_-35" CDS 2744961..2745458 /gene="ysxD" /locus_tag="BSU_28180" /old_locus_tag="BSU28180" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative integral inner membrane protein" /protein_id="NP_390696.2" /db_xref="EnsemblGenomes-Gn:BSU28180" /db_xref="EnsemblGenomes-Tr:CAB14778" /db_xref="GOA:P40736" /db_xref="SubtiList:BG11068" /db_xref="UniProtKB/Swiss-Prot:P40736" /translation="MKQKSILFPCLLLAASVYAWLESGQAELFSGQDQWPVLLMLLGA AFVYQGKKEAVTPHFFIGLLLFGIGLHFFAKPKWVWWPDDFEMLLFMIGFSLLVSTVQ KKEYVYEAVSMICFSLFLYFFKQIMAWLESAHIPTALLKEYWPFVFIGISLLLLLIKR KKSIR*" gene 2744961..2745458 /gene="ysxD" /locus_tag="BSU_28180" /old_locus_tag="BSU28180" promotor_-10 complement(2745294..2745312) /Source="Nicolas_upshift_promotors" /id="U2180" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=747 /SigmaFactorBS="gttggaatatgcgcagactcaagccatgccataattTGTTTG AaaaagtacaaaaacaGGGAAAAACAAATCATCGAcacagcttcatatacatattctt t" /listShort="S1064, S1063, hemA, hemX" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2745310) /Source="Nicolas_upshifts" /id="U2180" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=747 /SigmaFactorBS="gttggaatatgcgcagactcaagccatgccataattTGTTTG AaaaagtacaaaaacaGGGAAAAACAAATCATCGAcacagcttcatatacatattctt t" /listShort="S1064, S1063, hemA, hemX" /GFF_Attribute="listLong" S_feature complement(2745312..2745442) /Source="Nicolas_S_feature" /locus_tag="new_2879714_2879844_c" /HighExp="S5, S4, S8, S6, H2O2, S7, Etha, dia15, Diami, G180" /AntisenseName="ysxD" /AntisenseCor="-1.18079537254433E-2" /AntisenseRegPval="-0.1" /CDS_PredictionProba="NA" /TUshortSig="SigGF" /TUshortPSig="0.948" /TUlongSig="NA" /TUlongPSig="NA" /label="S1065" promotor_-35 complement(2745328..2745334) /Source="Nicolas_upshift_promotors" /id="U2180" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=747 /SigmaFactorBS="gttggaatatgcgcagactcaagccatgccataattTGTTTG AaaaagtacaaaaacaGGGAAAAACAAATCATCGAcacagcttcatatacatattctt t" /listShort="S1064, S1063, hemA, hemX" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(2745422..2745433) /Source="Nicolas_upshift_promotors" /id="U2181" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.948051948051948" /psig="0.948051948051948" /xcortree=1211 /SigmaFactorBS="tcaaaaaaatgataaaccggtagaggatcctctaccggtttt atttatCGTATAGatttttttcgttttATCAATAATAACaataaactgattccaataa a" /listShort="S1065, S1064, S1063" /listLong="hemA" /label="promotor_-10" upshifts complement(2745442) /Source="Nicolas_upshifts" /id="U2181" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.948051948051948" /psig="0.948051948051948" /xcortree=1211 /SigmaFactorBS="tcaaaaaaatgataaaccggtagaggatcctctaccggtttt atttatCGTATAGatttttttcgttttATCAATAATAACaataaactgattccaataa a" /listShort="S1065, S1064, S1063" /listLong="hemA" promotor_-35 complement(2745448..2745454) /Source="Nicolas_upshift_promotors" /id="U2181" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.948051948051948" /psig="0.948051948051948" /xcortree=1211 /SigmaFactorBS="tcaaaaaaatgataaaccggtagaggatcctctaccggtttt atttatCGTATAGatttttttcgttttATCAATAATAACaataaactgattccaataa a" /listShort="S1065, S1064, S1063" /listLong="hemA" /label="promotor_-35" CDS complement(2745480..2746067) /gene="engB" /locus_tag="BSU_28190" /old_locus_tag="BSU28190" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:12682299, 16997968, 17981968, 21360172, 21636901, 25771857, 26103561, 27484475" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12682299, 16997968, 17981968, 21360172, 21636901, 25771857, 26103561, 27484475; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="GTPase involved in ribosome 50S subunit assembly(maturation of the central 50S protuberance)" /protein_id="NP_390697.1" /db_xref="EnsemblGenomes-Gn:BSU28190" /db_xref="EnsemblGenomes-Tr:CAB14779" /db_xref="GOA:P38424" /db_xref="InterPro:IPR005225" /db_xref="InterPro:IPR006073" /db_xref="InterPro:IPR019987" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR030393" /db_xref="PDB:1SUL" /db_xref="PDB:1SVI" /db_xref="PDB:1SVW" /db_xref="SubtiList:BG10339" /db_xref="UniProtKB/Swiss-Prot:P38424" /translation="MKVTKSEIVISAVKPEQYPEGGLPEIALAGRSNVGKSSFINSLI NRKNLARTSSKPGKTQTLNFYIINDELHFVDVPGYGFAKVSKSEREAWGRMIETYITT REELKAVVQIVDLRHAPSNDDVQMYEFLKYYGIPVIVIATKADKIPKGKWDKHAKVVR QTLNIDPEDELILFSSETKKGKDEAWGAIKKMINR*" gene complement(2745480..2746067) /gene="engB" /locus_tag="BSU_28190" /old_locus_tag="BSU28190" downshifts complement(2745508) /Source="Nicolas_upshifts" /id="D1441" /incds=0 /nref=78 /ntot=212 /MaxReadThrough="4.03888" /MaxDrop="6.16077" /score="19.8235959" /energy="-13.4" /TU="NA" /idTUdmin="U2182" /TUdmin=0 /isTUend="TRUE" CDS complement(2746064..2748388) /gene="lonA" /locus_tag="BSU_28200" /old_locus_tag="BSU28200" /EC_number="3.4.21.53" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:10411757, 11325926, 15987505, 18689473, 20600124, 21546913, 25538299, 26677871" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10411757, 11325926, 15987505, 18689473, 20600124, 21546913, 25538299, 26677871; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="class III heat-shock ATP-dependent LonA protease" /protein_id="NP_390698.1" /db_xref="EnsemblGenomes-Gn:BSU28200" /db_xref="EnsemblGenomes-Tr:CAB14780" /db_xref="GOA:P37945" /db_xref="InterPro:IPR003111" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR003959" /db_xref="InterPro:IPR004815" /db_xref="InterPro:IPR008268" /db_xref="InterPro:IPR008269" /db_xref="InterPro:IPR014721" /db_xref="InterPro:IPR015947" /db_xref="InterPro:IPR020568" /db_xref="InterPro:IPR027065" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR027543" /db_xref="PDB:1X37" /db_xref="PDB:3M65" /db_xref="PDB:3M6A" /db_xref="SubtiList:BG10338" /db_xref="UniProtKB/Swiss-Prot:P37945" /translation="MAEELKRSIPLLPLRGLLVYPTMVLHLDVGRDKSVQALEQAMMH DHMIFLATQQDISIDEPGEDEIFTVGTYTKIKQMLKLPNGTIRVLVEGLKRAHIVKYN EHEDYTSVDIQLIHEDDSKDTEDEALMRTLLDHFDQYIKISKKISAETYAAVTDIEEP GRMADIVASHLPLKLKDKQDILETADVKDRLNKVIDFINNEKEVLEIEKKIGQRVKRS MERTQKEYYLREQMKAIQKELGDKEGKTGEVQTLTEKIEEAGMPDHVKETALKELNRY EKIPSSSAESSVIRNYIDWLVALPWTDETDDKLDLKEAGRLLDEEHHGLEKVKERILE YLAVQKLTKSLKGPILCLAGPPGVGKTSLAKSIAKSLGRKFVRISLGGVRDESEIRGH RRTYVGAMPGRIIQGMKKAGKLNPVFLLDEIDKMSSDFRGDPSSAMLEVLDPEQNSSF SDHYIEETFDLSKVLFIATANNLATIPGPLRDRMEIINIAGYTEIEKLEIVKDHLLPK QIKEHGLKKSNLQLRDQAILDIIRYYTREAGVRSLERQLAAICRKAAKAIVAEERKRI TVTEKNLQDFIGKRIFRYGQAETEDQVGVVTGLAYTTVGGDTLSIEVSLSPGKGKLIL TGKLGDVMRESAQAAFSYVRSKTEELGIEPDFHEKYDIHIHVPEGAVPKDGPSAGITM ATALVSALTGRAVSREVGMTGEITLRGRVLPIGGLKEKALGAHRAGLTTIIAPKDNEK DIEDIPESVREGLTFILASHLDEVLEHALVGEKK*" gene complement(2746064..2748388) /gene="lonA" /locus_tag="BSU_28200" /old_locus_tag="BSU28200" S_feature complement(2748389..2748500) /Source="Nicolas_S_feature" /locus_tag="new_2882791_2882902_c" /HighExp="Etha, dia15, LBGtran, dia5, Diami, H2O2, LBGexp, Lbexp, LoTm, Paraq" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.967" /TUlongSig="NA" /TUlongPSig="NA" /label="S1066" promotor_-10 complement(2748485..2748504) /Source="Nicolas_upshift_promotors" /id="U2182" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.646353646353646" /psig="0.967032967032967" /xcortree=2001 /SigmaFactorBS="ttgataatagggtttttttcatgaaggacatctttTCCTTTT TcatatcagaaagaAAGGGTATACTACGAGGAGActgttttatagaaaatggaaccat g" /listShort="S1066, lonA, ysxC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2748500) /Source="Nicolas_upshifts" /id="U2182" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.646353646353646" /psig="0.967032967032967" /xcortree=2001 /SigmaFactorBS="ttgataatagggtttttttcatgaaggacatctttTCCTTTT TcatatcagaaagaAAGGGTATACTACGAGGAGActgttttatagaaaatggaaccat g" /listShort="S1066, lonA, ysxC" /GFF_Attribute="listLong" promotor_-35 complement(2748518..2748525) /Source="Nicolas_upshift_promotors" /id="U2182" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.646353646353646" /psig="0.967032967032967" /xcortree=2001 /SigmaFactorBS="ttgataatagggtttttttcatgaaggacatctttTCCTTTT TcatatcagaaagaAAGGGTATACTACGAGGAGActgttttatagaaaatggaaccat g" /listShort="S1066, lonA, ysxC" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2748569..2750227) /gene="lonB" /locus_tag="BSU_28210" /old_locus_tag="BSU28210" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:10411757, 11325926, 18689473, 26428922" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10411757, 11325926, 18689473, 26428922; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="spore-specific ATP-dependent protease LonB" /protein_id="NP_390699.1" /db_xref="EnsemblGenomes-Gn:BSU28210" /db_xref="EnsemblGenomes-Tr:CAB14781" /db_xref="GOA:P42425" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR003959" /db_xref="InterPro:IPR008268" /db_xref="InterPro:IPR008269" /db_xref="InterPro:IPR014251" /db_xref="InterPro:IPR014721" /db_xref="InterPro:IPR020568" /db_xref="InterPro:IPR027065" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG11077" /db_xref="UniProtKB/Swiss-Prot:P42425" /translation="MSWTGIALFIQLFFGIIIGLYFWNLLKNQRTQKVTIDKESKKEM EQLRKMRAISLSEPLSEKVRPKSFKDIVGQEDGIKALKAALCGPNPQHVIVYGPPGVG KTAAARLVLEEAKKHKQSPFKEQAVFVELDATTARFDERGIADPLIGSVHDPIYQGAG AMGQAGIPQPKQGAVTHAHGGVLFIDEIGELHPIQMNKMLKVLEDRKVFLDSAYYSEE NTQIPNHIHDIFQNGLPADFRLIGATTRMPNEIPPAIRSRCLEVFFRELEKDELKTVA KTAADKIEKNISEEGLDLLTSYTRNGREAVNMIQIAAGMAVTENRKDITIEDIEWVIH SSQLTPKHEQKIGVEPQVGIVNGLAVYGPNSGSLLEIEVSVTAAQDKGSINITGIAEE ESIGSQSKSIRRKSMAKGSVENVLTVLRTMGMKPSDYDIHINFPGGIPIDGPSAGIAM AAGIFSAIHKIPIDNTVAMTGEISLNGLVKPIGGVIPKIKAAKQSGAKKVIIPYENQQ AILKQIDGIEIIAVKTFQEVLDEILVNPPTEQKPFHIEINKESV*" gene complement(2748569..2750227) /gene="lonB" /locus_tag="BSU_28210" /old_locus_tag="BSU28210" downshifts complement(2748588) /Source="Nicolas_upshifts" /id="D1442" /incds=0 /nref=24 /ntot=42 /MaxReadThrough="2.32825" /MaxDrop="4.82102" /score="7.30551887" /energy="-7.1" /TU="NA" /idTUdmin="U2183" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(2750271..2750289) /Source="Nicolas_upshift_promotors" /id="U2183" /multdbtbs="SigF" /comp="M3" /sig="SigEF" /pcomp="0.66933066933067" /psig="0.66933066933067" /xcortree=1167 /SigmaFactorBS="aggtttttttgcatgcaactcttccggaaaaaCGTTTAttcc cgtcttctatgGGAGATACTAGCAATCAGAggaatgaattggatacataaattgtttt t" /listShort="lonB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2750282) /Source="Nicolas_upshifts" /id="U2183" /multdbtbs="SigF" /comp="M3" /sig="SigEF" /pcomp="0.66933066933067" /psig="0.66933066933067" /xcortree=1167 /SigmaFactorBS="aggtttttttgcatgcaactcttccggaaaaaCGTTTAttcc cgtcttctatgGGAGATACTAGCAATCAGAggaatgaattggatacataaattgtttt t" /listShort="lonB" /GFF_Attribute="listLong" promotor_-35 complement(2750305..2750310) /Source="Nicolas_upshift_promotors" /id="U2183" /multdbtbs="SigF" /comp="M3" /sig="SigEF" /pcomp="0.66933066933067" /psig="0.66933066933067" /xcortree=1167 /SigmaFactorBS="aggtttttttgcatgcaactcttccggaaaaaCGTTTAttcc cgtcttctatgGGAGATACTAGCAATCAGAggaatgaattggatacataaattgtttt t" /listShort="lonB" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2750379..2751641) /gene="clpX" /locus_tag="BSU_28220" /old_locus_tag="BSU28220" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:11395451, 11807061, 12354604, 12761164, 14679237, 15948963, 16899079, 17827297, 17981983, 18662407, 19136590, 25433860, 27014237" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11395451, 11807061, 12354604, 12761164, 14679237, 15948963, 16899079, 17827297, 17981983, 18662407, 19136590, 25433860, 27014237; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="protein unfolding ATPase required for presentation of proteins to proteases; Maxwell's demon" /protein_id="NP_390700.2" /db_xref="EnsemblGenomes-Gn:BSU28220" /db_xref="EnsemblGenomes-Tr:CAB14782" /db_xref="GOA:P50866" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR003959" /db_xref="InterPro:IPR004487" /db_xref="InterPro:IPR010603" /db_xref="InterPro:IPR019489" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG11387" /db_xref="UniProtKB/Swiss-Prot:P50866" /translation="MFKFNEEKGQLKCSFCGKTQDQVRKLVAGPGVYICDECIELCTE IVEEELGTEEEVEFKDVPKPQEIREILNEYVIGQDQAKKSLAVAVYNHYKRINSNSKV DDVELSKSNISLIGPTGSGKTLLAQTLARILNVPFAIADATSLTEAGYVGEDVENILL KLIQAADYDVEKAEKGIIYIDEIDKVARKSENPSITRDVSGEGVQQALLKILEGTVAS VPPQGGRKHPHQEFIQIDTTNILFICGGAFDGIEQIIKRRLGQKVIGFGADNKAADLE KEDLLSKVLPEDLLRFGLIPEFIGRLPVIASLEKLDEEALVAILTKPKNALVKQFKKM LELDNVELEFEEEALSEIAKKAIERKTGARGLRSIIEGIMLDVMFELPSRDDIEKCVI TGATVTHGEPPRLLLKDGTEVSQDKTSA*" gene complement(2750379..2751641) /gene="clpX" /locus_tag="BSU_28220" /old_locus_tag="BSU28220" downshifts complement(2750389) /Source="Nicolas_upshifts" /id="D1443" /incds=0 /nref=256 /ntot=333 /MaxReadThrough="2.8818" /MaxDrop="7.82186" /score="40.299167" /energy="-18.9" /TU="U2185" /idTUdmin="U2184" /TUdmin="-19" /isTUend="TRUE" S_feature complement(2751642..2751731) /Source="Nicolas_S_feature" /locus_tag="new_2886044_2886133_c" /HighExp="dia15, dia5, Salt, Diami, C90, H2O2, Paraq, Oxctl, S1, Heat" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="1, 1" /TUlongSig="SigA, SigA, SigA" /TUlongPSig="1, 0.998, 0.896" /label="S1067" promotor_-10 complement(2751719..2751738) /Source="Nicolas_upshift_promotors" /id="U2184" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.883116883116883" /psig=1 /xcortree=1875 /SigmaFactorBS="atacatatagaatgtgcaagtcagaaacacattgTTACCGTC tttttggaaagTATGGTAAAATGCAATACATactcgttcgtttcaagaatcattttct t" /listShort="S1067, clpX" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2751731) /Source="Nicolas_upshifts" /id="U2184" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.883116883116883" /psig=1 /xcortree=1875 /SigmaFactorBS="atacatatagaatgtgcaagtcagaaacacattgTTACCGTC tttttggaaagTATGGTAAAATGCAATACATactcgttcgtttcaagaatcattttct t" /listShort="S1067, clpX" /GFF_Attribute="listLong" S_feature complement(2751733..2751864) /Source="Nicolas_S_feature" /locus_tag="new_2886135_2886266_c" /HighExp="H2O2, dia15, Paraq, Oxctl, G180, G135, HPh, G150, LPh, C90" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="1, 0.998" /TUlongSig="SigA, SigA" /TUlongPSig="1, 0.896" /label="S1068" promotor_-35 complement(2751750..2751757) /Source="Nicolas_upshift_promotors" /id="U2184" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.883116883116883" /psig=1 /xcortree=1875 /SigmaFactorBS="atacatatagaatgtgcaagtcagaaacacattgTTACCGTC tttttggaaagTATGGTAAAATGCAATACATactcgttcgtttcaagaatcattttct t" /listShort="S1067, clpX" /GFF_Attribute="listLong" /label="promotor_-35" downshifts complement(2751909) /Source="Nicolas_upshifts" /id="D1444" /incds=0 /nref=4 /ntot=16 /MaxReadThrough="8.26501" /MaxDrop="4.34985" /score="-0.284489083" /energy="-10.7" /TU="U2185,U2190" /idTUdmin="U2190" /TUdmin="-153" /isTUend="FALSE" CDS complement(2751913..2753187) /gene="tig" /locus_tag="BSU_28230" /old_locus_tag="BSU28230" /EC_number="5.2.1.8" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:9748346, 12224648, 16156784, 17021213" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9748346, 12224648, 16156784, 17021213; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="prolyl isomerase (trigger factor)" /protein_id="NP_390701.1" /db_xref="EnsemblGenomes-Gn:BSU28230" /db_xref="EnsemblGenomes-Tr:CAB14783" /db_xref="GOA:P80698" /db_xref="InterPro:IPR001179" /db_xref="InterPro:IPR005215" /db_xref="InterPro:IPR008880" /db_xref="InterPro:IPR008881" /db_xref="InterPro:IPR027304" /db_xref="InterPro:IPR036611" /db_xref="SubtiList:BG19023" /db_xref="UniProtKB/Swiss-Prot:P80698" /translation="MSVKWEKQEGNEGVLTVEVDAETFKTALDDAFKKVVKQVSIPGF RKGKIPRGLFEQRFGVEALYQDALDILLPVEYPKAVEEAGIEPVDRPEIDVEKIEKGE SLIFTAKVTVKPEVKLGEYKGLGIEKDDTTVTDEDVQNELKALQERQAELVVKEEGAV EEGNTVVLDFEGFVDGEAFEGGKAENYSLEVGSGSFIPGFEDQLVGLEAGAEKDVEVT FPEEYHAEDLAGKPAVFKVKIHEIKAKELPELDDEFAKDIDEEVETLAELTEKTKKRL EEAKENEADAKLREELVLKASENAEIDVPQAMVDTELDRMLKEFEQRLQMQGMNLELY TQFSGQDEAALKEQMKEDAEKRVKSNLTLEAIAKAENLEVSDEEVDAELTKMAEAYNM PVENIKQAIGSTDAMKEDLKVRKAIDFLVENR*" gene complement(2751913..2753187) /gene="tig" /locus_tag="BSU_28230" /old_locus_tag="BSU28230" S_feature complement(2753188..2753377) /Source="Nicolas_S_feature" /locus_tag="new_2887590_2887779_c" /HighExp="H2O2, HPh, BMM, dia15, T-4.40H, G180, Paraq, Oxctl, LBGexp, MG 25" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="1, 0.998" /TUlongSig="SigA, SigA" /TUlongPSig="1, 0.896" /label="S1069" promotor_-10 complement(2753364..2753383) /Source="Nicolas_upshift_promotors" /id="U2185" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.873126873126873" /psig=1 /xcortree=2561 /SigmaFactorBS="ttgaagaaatttcttatttgtaaatcgcgccatatAGTTGaa agcgctatgtgtTATGTTATAATATAGTGGTTgtatttgtgtataacgggttataaga a" /listShort="S1069, tig, S1068, S1067, clpX" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2753377) /Source="Nicolas_upshifts" /id="U2185" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.873126873126873" /psig=1 /xcortree=2561 /SigmaFactorBS="ttgaagaaatttcttatttgtaaatcgcgccatatAGTTGaa agcgctatgtgtTATGTTATAATATAGTGGTTgtatttgtgtataacgggttataaga a" /listShort="S1069, tig, S1068, S1067, clpX" /GFF_Attribute="listLong" promotor_-35 complement(2753398..2753402) /Source="Nicolas_upshift_promotors" /id="U2185" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.873126873126873" /psig=1 /xcortree=2561 /SigmaFactorBS="ttgaagaaatttcttatttgtaaatcgcgccatatAGTTGaa agcgctatgtgtTATGTTATAATATAGTGGTTgtatttgtgtataacgggttataaga a" /listShort="S1069, tig, S1068, S1067, clpX" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2753415..2754419) /gene="ysoA" /locus_tag="BSU_28240" /old_locus_tag="BSU28240" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative hydrolase" /protein_id="NP_390702.2" /db_xref="EnsemblGenomes-Gn:BSU28240" /db_xref="EnsemblGenomes-Tr:CAB14784" /db_xref="InterPro:IPR011990" /db_xref="InterPro:IPR013026" /db_xref="InterPro:IPR019734" /db_xref="SubtiList:BG12338" /db_xref="UniProtKB/Swiss-Prot:P94569" /translation="MTHDKKNAKIIPFPHLKDRLVEKGMSSLKEKKYQEALELFSEAM KYDDTESDLHLGMAICFLELGELEEAESVCEKMLKEGYGHYFTVLQVYMTILIQLKKY EEVKSTIEAVLEENQLPAESAEQFYKLLDFSRKMTDPDREDEAWAEEYEDTIDTEKVL ASPEEQMNLIHSLKDRNVAKYTGLLKTILQDPSAHPIIKTMIVMLLAEHEYSKPVHIS KFGESLTIEPSEIVPPDAAPILHRVLRVLDETLGNENPTLYAAVEELWRRHLYVLYPF QPKLLSADLWAAALHKVGYEMHGIEIESEELHMMYEFTDRELDEACTMLKDIEEISYL *" gene complement(2753415..2754419) /gene="ysoA" /locus_tag="BSU_28240" /old_locus_tag="BSU28240" promotor_-10 complement(2754444..2754463) /Source="Nicolas_upshift_promotors" /id="U2186" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.609390609390609" /psig=1 /xcortree=1870 /SigmaFactorBS="ttgtccggcggctttttttgcctggtgaaacctttcatttCT TGTTTTtgttcacaggtGTTGATACACTTGAACAAAAtaaatgcctgaaaggaatata g" /listShort="ysoA" /listLong="S1069, tig, S1068, S1067, clpX" /label="promotor_-10" upshifts complement(2754462) /Source="Nicolas_upshifts" /id="U2186" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.609390609390609" /psig=1 /xcortree=1870 /SigmaFactorBS="ttgtccggcggctttttttgcctggtgaaacctttcatttCT TGTTTTtgttcacaggtGTTGATACACTTGAACAAAAtaaatgcctgaaaggaatata g" /listShort="ysoA" /listLong="S1069, tig, S1068, S1067, clpX" promotor_-35 complement(2754475..2754482) /Source="Nicolas_upshift_promotors" /id="U2186" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.609390609390609" /psig=1 /xcortree=1870 /SigmaFactorBS="ttgtccggcggctttttttgcctggtgaaacctttcatttCT TGTTTTtgttcacaggtGTTGATACACTTGAACAAAAtaaatgcctgaaaggaatata g" /listShort="ysoA" /listLong="S1069, tig, S1068, S1067, clpX" /label="promotor_-35" CDS complement(2754538..2755137) /gene="leuD" /locus_tag="BSU_28250" /old_locus_tag="BSU28250" /EC_number="4.2.1.33" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 15228537, 15916605; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="3-isopropylmalate dehydratase (small subunit)" /protein_id="NP_390703.1" /db_xref="EnsemblGenomes-Gn:BSU28250" /db_xref="EnsemblGenomes-Tr:CAB14785" /db_xref="GOA:P94568" /db_xref="InterPro:IPR000573" /db_xref="InterPro:IPR004431" /db_xref="InterPro:IPR015928" /db_xref="InterPro:IPR033940" /db_xref="SubtiList:BG11950" /db_xref="UniProtKB/Swiss-Prot:P94568" /translation="MEPLKSHTGKAAVLNRINVDTDQIIPKQFLKRIERTGYGRFAFF DWRYDANGEPNPEFELNQPVYQGASILIAGENFGCGSSREHAPWALDDYGFKIIIAPS FADIFHQNCFKNGMLPIRMPYDNWKQLVGQYENQSLQMTVDLENQLIHDSEGNQISFE VDPHWKEMLINGYDEISLTLLLEDEIKQFESQRSSWLQA*" gene complement(2754538..2755137) /gene="leuD" /locus_tag="BSU_28250" /old_locus_tag="BSU28250" downshifts complement(2754559) /Source="Nicolas_upshifts" /id="D1445" /incds=0 /nref=5 /ntot=111 /MaxReadThrough="6.76876" /MaxDrop="3.81278" /score="12.2084487" /energy="-9.9" /TU="U2190,U2191" /idTUdmin="U2186" /TUdmin="-1176" /isTUend="FALSE" CDS complement(2755150..2756568) /gene="leuC" /locus_tag="BSU_28260" /old_locus_tag="BSU28260" /EC_number="4.2.1.33" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 15228537, 15916605; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="3-isopropylmalate dehydratase (large subunit)" /protein_id="NP_390704.1" /db_xref="EnsemblGenomes-Gn:BSU28260" /db_xref="EnsemblGenomes-Tr:CAB14786" /db_xref="GOA:P80858" /db_xref="InterPro:IPR001030" /db_xref="InterPro:IPR004430" /db_xref="InterPro:IPR015931" /db_xref="InterPro:IPR015932" /db_xref="InterPro:IPR018136" /db_xref="InterPro:IPR033941" /db_xref="InterPro:IPR036008" /db_xref="SubtiList:BG11949" /db_xref="UniProtKB/Swiss-Prot:P80858" /translation="MMPRTIIEKIWDQHIVKHGEGKPDLLYIDLHLIHEVTSPQAFEG LRQKGRKVRRPQNTFATMDHNIPTVNRFEIKDEVAKRQVTALERNCEEFGVRLADLHS VDQGIVHVVGPELGLTLPGKTIVCGDSHTSTHGAFGALAFGIGTSEVEHVLSTQTLWQ QRPKTLEVRVDGTLQKGVTAKDVILAVIGKYGVKFGTGYVIEYTGEVFRNMTMDERMT VCNMSIEAGARAGLIAPDEVTFEYCKNRKYTPKGEEFDKAVEEWKALRTDPGAVYDKS IVLDGNKISPMVTWGINPGMVLPVDSEVPAPESFSAEDDKKEAIRAYEYMGLTPHQKI EDIKVEHVFIGSCTNSRMTDLRQAADMIKGKKVADSVRAIVVPGSQSVKLQAEKEGLD QIFLEAGFEWRESGCSMCLSMNNDVVPEGERCASTSNRNFEGRQGKGARTHLVSPAMA AMAAIHGHFVDVRKFYQEKTVV*" gene complement(2755150..2756568) /gene="leuC" /locus_tag="BSU_28260" /old_locus_tag="BSU28260" promotor_-35 2756457..2756461 /Source="Nicolas_upshift_promotors" /id="U2187" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.98901098901099" /psig="0.001998001998002" /xcortree=28 /SigmaFactorBS="ctttcttcccttttgtctcaagccttcaaatgcctgaggagA CGTCacctcatgaatgagGTGCAaatcaatatagagaagatccggctttccctcacca t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2756476..2756480 /Source="Nicolas_upshift_promotors" /id="U2187" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.98901098901099" /psig="0.001998001998002" /xcortree=28 /SigmaFactorBS="ctttcttcccttttgtctcaagccttcaaatgcctgaggagA CGTCacctcatgaatgagGTGCAaatcaatatagagaagatccggctttccctcacca t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2756476 /Source="Nicolas_upshifts" /id="U2187" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.98901098901099" /psig="0.001998001998002" /xcortree=28 /SigmaFactorBS="ctttcttcccttttgtctcaagccttcaaatgcctgaggagA CGTCacctcatgaatgagGTGCAaatcaatatagagaagatccggctttccctcacca t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" CDS complement(2756618..2757715) /gene="leuB" /locus_tag="BSU_28270" /old_locus_tag="BSU28270" /EC_number="1.1.1.85" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:10095787, 15228537, 15916605, 17389690" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10095787, 15228537, 15916605, 17389690; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="3-isopropylmalate dehydrogenase" /protein_id="NP_390705.2" /db_xref="EnsemblGenomes-Gn:BSU28270" /db_xref="EnsemblGenomes-Tr:CAB14787" /db_xref="GOA:P05645" /db_xref="InterPro:IPR004429" /db_xref="InterPro:IPR019818" /db_xref="InterPro:IPR024084" /db_xref="SubtiList:BG10675" /db_xref="UniProtKB/Swiss-Prot:P05645" /translation="MKKRIALLPGDGIGPEVLESATDVLKSVAERFNHEFEFEYGLIG GAAIDEHHNPLPEETVAACKNADAILLGAVGGPKWDQNPSELRPEKGLLSIRKQLDLF ANLRPVKVFESLSDASPLKKEYIDNVDFVIVRELTGGLYFGQPSKRYVNTEGEQEAVD TLFYKRTEIERVIREGFKMAAARKGKVTSVDKANVLESSRLWREVAEDVAQEFPDVKL EHMLVDNAAMQLIYAPNQFDVVVTENMFGDILSDEASMLTGSLGMLPSASLSSSGLHL FEPVHGSAPDIAGKGMANPFAAILSAAMLLRTSFGLEEEAKAVEDAVNKVLASGKRTR DLARSEEFSSTQAITEEVKAAIMSENTISNV*" gene complement(2756618..2757715) /gene="leuB" /locus_tag="BSU_28270" /old_locus_tag="BSU28270" CDS complement(2757736..2759292) /gene="leuA" /locus_tag="BSU_28280" /old_locus_tag="BSU28280" /EC_number="2.3.3.13" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 15228537, 15916605, 16330546; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="2-isopropylmalate synthase" /protein_id="NP_390706.1" /db_xref="EnsemblGenomes-Gn:BSU28280" /db_xref="EnsemblGenomes-Tr:CAB14788" /db_xref="GOA:P94565" /db_xref="InterPro:IPR000891" /db_xref="InterPro:IPR002034" /db_xref="InterPro:IPR005671" /db_xref="InterPro:IPR013709" /db_xref="InterPro:IPR013785" /db_xref="InterPro:IPR036230" /db_xref="SubtiList:BG11948" /db_xref="UniProtKB/Swiss-Prot:P94565" /translation="MRKINFFDTTLRDGEQSPGVNLNTQEKLAIAKQLERLGADIIEA GFPASSRGDFLAVQEIARTIKNCSVTGLARCVKGDIDAAWEALKDGAQPRIHVFIATS DIHLKHKLKMTREQVIERAVGMVKYAKERFPIVQWSAEDACRTELPFLAEIVEKVIDA GASVINLPDTVGYLAPAEYGNIFKYMKENVPNIHKAKLSAHCHDDLGMAVANSLAAIE NGADQIECAVNGIGERAGNAALEEIAVALHTRKDFYQVETGITLNEIKRTSDLVSKLT GMAVPRNKAVVGDNAFAHESGIHQDGFLKEKSTYEIISPELVGVTADALVLGKHSGRH AFKDRLTALGFQFDSEEINKFFTMFKELTEKKKEITDEDLVSLILEEKVTDRKIGYEF LSLQVHYGTSQVPTATLSLKNQENAQLIQEAATGAGSVEAIYNTLERCIDKDVELLDY RIQSNRKGEDAFAQVYVRVLVNGKESAGRGIAQDVLEASAKAYLNAVNRQLVFQSNMS GLKNHTAVGS*" gene complement(2757736..2759292) /gene="leuA" /locus_tag="BSU_28280" /old_locus_tag="BSU28280" promotor_-35 2758132..2758135 /Source="Nicolas_upshift_promotors" /id="U2188" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.831168831168831" /psig=1 /xcortree=1529 /SigmaFactorBS="cttgttccgtaatgtacttgcagagaaagaaattcataccca atCTTGcgatctgttactttTTCTTCTAAAATAAGAGAAAcaagatcctcatcagtga t" /listShort="S1070" /GFF_Attribute="listLong" /label="promotor_-35" S_feature 2758148..2760589 /Source="Nicolas_S_feature" /locus_tag="new_2892550_2894991" /HighExp="Lbstat, C30, T0.30H, M9-stat, T1.30H, H2O2, M0t90, T2.0H, Salt, BC" /AntisenseName="ilvC" /AntisenseCor="-0.51305153097242795" /AntisenseRegPval="-18.7" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1070" upshifts 2758148 /Source="Nicolas_upshifts" /id="U2188" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.831168831168831" /psig=1 /xcortree=1529 /SigmaFactorBS="cttgttccgtaatgtacttgcagagaaagaaattcataccca atCTTGcgatctgttactttTTCTTCTAAAATAAGAGAAAcaagatcctcatcagtga t" /listShort="S1070" /GFF_Attribute="listLong" promotor_-10 2758150..2758169 /Source="Nicolas_upshift_promotors" /id="U2188" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.831168831168831" /psig=1 /xcortree=1529 /SigmaFactorBS="cttgttccgtaatgtacttgcagagaaagaaattcataccca atCTTGcgatctgttactttTTCTTCTAAAATAAGAGAAAcaagatcctcatcagtga t" /listShort="S1070" /GFF_Attribute="listLong" /label="promotor_-10" CDS complement(2759279..2760307) /gene="ilvC" /locus_tag="BSU_28290" /old_locus_tag="BSU28290" /EC_number="1.1.1.86" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 15228537, 15916605, 25393291, 25849365; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="acetohydroxy-acid isomeroreductase (NADP-dependent)" /protein_id="NP_390707.1" /db_xref="EnsemblGenomes-Gn:BSU28290" /db_xref="EnsemblGenomes-Tr:CAB14789" /db_xref="GOA:P37253" /db_xref="InterPro:IPR000506" /db_xref="InterPro:IPR008927" /db_xref="InterPro:IPR013023" /db_xref="InterPro:IPR013116" /db_xref="InterPro:IPR013328" /db_xref="InterPro:IPR014359" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG10672" /db_xref="UniProtKB/Swiss-Prot:P37253" /translation="MVKVYYNGDIKENVLAGKTVAVIGYGSQGHAHALNLKESGVDVI VGVRQGKSFTQAQEDGHKVFSVKEAAAQAEIIMVLLPDEQQQKVYEAEIKDELTAGKS LVFAHGFNVHFHQIVPPADVDVFLVAPKGPGHLVRRTYEQGAGVPALFAIYQDVTGEA RDKALAYAKGIGGARAGVLETTFKEETETDLFGEQAVLCGGLSALVKAGFETLTEAGY QPELAYFECLHELKLIVDLMYEEGLAGMRYSISDTAQWGDFVSGPRVVDAKVKESMKE VLKDIQNGTFAKEWIVENQVNRPRFNAINASENEHQIEVVGRKLREMMPFVKQGKKKE AVVSVAQN*" gene complement(2759279..2760307) /gene="ilvC" /locus_tag="BSU_28290" /old_locus_tag="BSU28290" CDS complement(2760331..2760849) /gene="ilvH" /locus_tag="BSU_28300" /old_locus_tag="BSU28300" /EC_number="2.2.1.6" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1c: Function from experimental evidences in the studied genus; PubMedId: 10229948, 14702326, 15228537, 15916605; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="acetohydroxy-acid synthase (small subunit)" /protein_id="NP_390708.2" /db_xref="EnsemblGenomes-Gn:BSU28300" /db_xref="EnsemblGenomes-Tr:CAB14790" /db_xref="GOA:P37252" /db_xref="InterPro:IPR002912" /db_xref="InterPro:IPR004789" /db_xref="InterPro:IPR019455" /db_xref="SubtiList:BG10671" /db_xref="UniProtKB/Swiss-Prot:P37252" /translation="MKRIITLTVVNRSGVLNRITGLFTKRHYNIESITVGHTETAGVS RITFVVHVEGENDVEQLTKQLNKQIDVLKVTDITNQSIVQRELALIKVVSAPSTRTEI NGIIEPFRASVVDVSRDSIVVQVTGESNKIEALIELLKPYGIKEIARTGTTAFARGTQ QKASSNKTISIV*" gene complement(2760331..2760849) /gene="ilvH" /locus_tag="BSU_28300" /old_locus_tag="BSU28300" promotor_-35 2760570..2760573 /Source="Nicolas_upshift_promotors" /id="U2189" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.947052947052947" /psig="0.041958041958042" /xcortree=26 /SigmaFactorBS="ctatgattccattaatctctgttcttgttgaaggtgcggAGA CaaccttgattaaggcCAGCTccctctggacaatcgattgatttgtgatgtctgtgac t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2760589..2760593 /Source="Nicolas_upshift_promotors" /id="U2189" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.947052947052947" /psig="0.041958041958042" /xcortree=26 /SigmaFactorBS="ctatgattccattaatctctgttcttgttgaaggtgcggAGA CaaccttgattaaggcCAGCTccctctggacaatcgattgatttgtgatgtctgtgac t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2760591 /Source="Nicolas_upshifts" /id="U2189" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.947052947052947" /psig="0.041958041958042" /xcortree=26 /SigmaFactorBS="ctatgattccattaatctctgttcttgttgaaggtgcggAGA CaaccttgattaaggcCAGCTccctctggacaatcgattgatttgtgatgtctgtgac t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" CDS complement(2760846..2762570) /gene="ilvB" /locus_tag="BSU_28310" /old_locus_tag="BSU28310" /EC_number="2.2.1.6" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1c: Function from experimental evidences in the studied genus; PubMedId: 10229948, 14702326, 15228537, 15916605; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="acetohydroxy-acid synthase (large subunit)" /protein_id="NP_390709.1" /db_xref="EnsemblGenomes-Gn:BSU28310" /db_xref="EnsemblGenomes-Tr:CAB14791" /db_xref="GOA:P37251" /db_xref="InterPro:IPR011766" /db_xref="InterPro:IPR012000" /db_xref="InterPro:IPR012001" /db_xref="InterPro:IPR012846" /db_xref="InterPro:IPR029035" /db_xref="InterPro:IPR029061" /db_xref="SubtiList:BG10670" /db_xref="UniProtKB/Swiss-Prot:P37251" /translation="MGTNVQVDSASAECTQTMSGALMLIESLKKEKVEMIFGYPGGAV LPIYDKLYNSGLVHILPRHEQGAIHAAEGYARVSGKPGVVIATSGPGATNLVTGLADA MIDSLPLVVFTGQVATSVIGSDAFQEADILGITMPVTKHSYQVRQPEDLPRIIKEAFH IATTGRPGPVLIDIPKDVATIEGEFSYDHEMNLPGYQPTTEPNYLQIRKLVEAVSSAK KPVILAGAGVLHGKASEELKNYAEQQQIPVAHTLLGLGGFPADHPLFLGMAGMHGTYT ANMALHECDLLISIGARFDDRVTGNLKHFARNAKIAHIDIDPAEIGKIMKTQIPVVGD SKIVLQELIKQDGKQSDSSEWKKQLAEWKEEYPLWYVDNEEEGFKPQKLIEYIHQFTK GEAIVATDVGQHQMWSAQFYPFQKADKWVTSGGLGTMGFGLPAAIGAQLAEKDATVVA VVGDGGFQMTLQELDVIRELNLPVKVVILNNACLGMVRQWQEIFYEERYSESKFASQP DFVKLSEAYGIKGIRISSEAEAKEKLEEALTSREPVVIDVRVASEEKVFPMVAPGKGL HEMVGVKP*" gene complement(2760846..2762570) /gene="ilvB" /locus_tag="BSU_28310" /old_locus_tag="BSU28310" S_feature complement(2762571..2762691) /Source="Nicolas_S_feature" /locus_tag="new_2896973_2897093_c" /HighExp="T-5.40H, T-4.40H, S2, MG 120, Glucon, GM-0.2, T-2.40H, GM-0.1, HiOs, T-3.40H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="0.998, 0.896" /TUlongSig="NA" /TUlongPSig="NA" /label="S1071" misc_RNA complement(2762692..2762938) /gene="tboILV" /locus_tag="BSU_misc_RNA_45" /product="T-box controlling synthesis of branched chain amino acids" /note="Evidence 2b: Function from indirect experimental evidences (e.g. phenotypes); PubMedId: 1317842, 9098041, 12165569, 12547201; Product type n: RNA" /function="16.3: Control" gene complement(2762692..2762938) /gene="tboILV" /locus_tag="BSU_misc_RNA_45" downshifts complement(2762735) /Source="Nicolas_upshifts" /id="D1446" /incds=0 /nref=18 /ntot=78 /MaxReadThrough="7.67475" /MaxDrop="4.2339" /score="5.33237345" /energy="-13.8" /TU="U2190,U2191" /idTUdmin="U2195" /TUdmin=2682 /isTUend="FALSE" S_feature complement(2762939..2763065) /Source="Nicolas_S_feature" /locus_tag="new_2897341_2897467_c" /HighExp="LoTm, HiOs, T-3.40H, BC, B60, Pyr, GM 15, T-5.40H, UNK1, MG 120" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="0.998, 0.896" /TUlongSig="NA" /TUlongPSig="NA" /label="S1072" promotor_-10 complement(2763047..2763066) /Source="Nicolas_upshift_promotors" /id="U2190" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.867132867132867" /psig="0.998001998001998" /xcortree=2905 /SigmaFactorBS="tgattaatcaaaattgtctaataattttaaaaaatgcTGTTG ACActgcgtccaaagcgGCGTAATATGAGTTCAACAAaagataaatgcaagcttcaca a" /listShort="S1072, NA, S1071, ilvB, ilvH, ilvC, leuA, leuB, leuC, leuD, ysoA, S1069, tig, S1068" /listLong="S1067, clpX" /label="promotor_-10" upshifts complement(2763065) /Source="Nicolas_upshifts" /id="U2190" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.867132867132867" /psig="0.998001998001998" /xcortree=2905 /SigmaFactorBS="tgattaatcaaaattgtctaataattttaaaaaatgcTGTTG ACActgcgtccaaagcgGCGTAATATGAGTTCAACAAaagataaatgcaagcttcaca a" /listShort="S1072, NA, S1071, ilvB, ilvH, ilvC, leuA, leuB, leuC, leuD, ysoA, S1069, tig, S1068" /listLong="S1067, clpX" S_feature complement(2763067..2763197) /Source="Nicolas_S_feature" /locus_tag="new_2897469_2897599_c" /HighExp="Cold, S8, S0, S7, Mal, S6, G135, M9-stat, C30, S5" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.896" /TUlongSig="NA" /TUlongPSig="NA" /label="S1073" promotor_-35 complement(2763081..2763088) /Source="Nicolas_upshift_promotors" /id="U2190" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.867132867132867" /psig="0.998001998001998" /xcortree=2905 /SigmaFactorBS="tgattaatcaaaattgtctaataattttaaaaaatgcTGTTG ACActgcgtccaaagcgGCGTAATATGAGTTCAACAAaagataaatgcaagcttcaca a" /listShort="S1072, NA, S1071, ilvB, ilvH, ilvC, leuA, leuB, leuC, leuD, ysoA, S1069, tig, S1068" /listLong="S1067, clpX" /label="promotor_-35" promotor_-10 complement(2763192..2763211) /Source="Nicolas_upshift_promotors" /id="U2191" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.747252747252747" /psig="0.896103896103896" /xcortree=310 /SigmaFactorBS="tgttataaaatcttccatgtttatataaaattaAATAattct ggtgtattCTTGATAGATTAATAAAAAAattataaaaacttttaacatttgcaattcc t" /listShort="S1073, S1072, NA, S1071, ilvB, ilvH, ilvC, leuA, leuB, leuC, leuD, ysoA" /listLong="S1069, tig, S1068, S1067, clpX" /label="promotor_-10" upshifts complement(2763201) /Source="Nicolas_upshifts" /id="U2191" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.747252747252747" /psig="0.896103896103896" /xcortree=310 /SigmaFactorBS="tgttataaaatcttccatgtttatataaaattaAATAattct ggtgtattCTTGATAGATTAATAAAAAAattataaaaacttttaacatttgcaattcc t" /listShort="S1073, S1072, NA, S1071, ilvB, ilvH, ilvC, leuA, leuB, leuC, leuD, ysoA" /listLong="S1069, tig, S1068, S1067, clpX" promotor_-35 complement(2763225..2763228) /Source="Nicolas_upshift_promotors" /id="U2191" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.747252747252747" /psig="0.896103896103896" /xcortree=310 /SigmaFactorBS="tgttataaaatcttccatgtttatataaaattaAATAattct ggtgtattCTTGATAGATTAATAAAAAAattataaaaacttttaacatttgcaattcc t" /listShort="S1073, S1072, NA, S1071, ilvB, ilvH, ilvC, leuA, leuB, leuC, leuD, ysoA" /listLong="S1069, tig, S1068, S1067, clpX" /label="promotor_-35" promotor_-35 2763323..2763332 /Source="Nicolas_upshift_promotors" /id="U2192" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1322 /SigmaFactorBS="ctgacagatcatcttgcaatccatttcaatttcggATAGGCA CTTctcttgttccctcGGCATACATTAATGATATCTtgcaaagaaaaggtgatacgat g" /listShort="ysnD, S1074, ysnE" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2763346..2763365 /Source="Nicolas_upshift_promotors" /id="U2192" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1322 /SigmaFactorBS="ctgacagatcatcttgcaatccatttcaatttcggATAGGCA CTTctcttgttccctcGGCATACATTAATGATATCTtgcaaagaaaaggtgatacgat g" /listShort="ysnD, S1074, ysnE" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2763348 /Source="Nicolas_upshifts" /id="U2192" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1322 /SigmaFactorBS="ctgacagatcatcttgcaatccatttcaatttcggATAGGCA CTTctcttgttccctcGGCATACATTAATGATATCTtgcaaagaaaaggtgatacgat g" /listShort="ysnD, S1074, ysnE" /GFF_Attribute="listLong" CDS 2763386..2763721 /gene="cotQ" /locus_tag="BSU_28320" /old_locus_tag="BSU28320" /experiment="publication(s) with functional evidences, PMID:19933362" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 19933362; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="inner spore coat protein" /protein_id="NP_390710.1" /db_xref="EnsemblGenomes-Gn:BSU28320" /db_xref="EnsemblGenomes-Tr:CAB14792" /db_xref="SubtiList:BG12335" /db_xref="UniProtKB/Swiss-Prot:P94563" /translation="MNKSFADMQGFPAGFPSFPNFPQQYYPAVPPFYQQSQQPFGGYG YGQPFSQAYSPLTTPSGMYSSFPYASGFYGQQFSGAGFSGHGGSLSAPAIHAGGFSGA PGVHGGFRY*" gene 2763386..2763721 /gene="cotQ" /locus_tag="BSU_28320" /old_locus_tag="BSU28320" downshifts 2763715 /Source="Nicolas_upshifts" /id="D1447" /incds=0 /nref=14 /ntot=36 /MaxReadThrough="3.79194" /MaxDrop="6.48183" /score="11.836855" /energy="-13" /TU="U2192" /idTUdmin="U2193" /TUdmin="-220" /isTUend="FALSE" promotor_-35 2763802..2763809 /Source="Nicolas_upshift_promotors" /id="U2193" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.486513486513487" /psig="0.954045954045954" /xcortree=614 /SigmaFactorBS="ttttaaaacgacttcacaagtacagtcacattttctgTCTTT ATAtttggaaacaggaTGGAATATGATTAAGATGAAttgaacgatattctgcacaatc c" /listShort="S1074" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2763823..2763842 /Source="Nicolas_upshift_promotors" /id="U2193" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.486513486513487" /psig="0.954045954045954" /xcortree=614 /SigmaFactorBS="ttttaaaacgacttcacaagtacagtcacattttctgTCTTT ATAtttggaaacaggaTGGAATATGATTAAGATGAAttgaacgatattctgcacaatc c" /listShort="S1074" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 2763825..2763889 /Source="Nicolas_S_feature" /locus_tag="new_2898227_2898291" /HighExp="S5, S6, S8, S7, B36, S4, S3, B60, BT, Pyr" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigK" /TUshortPSig="0.954, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S1074" upshifts 2763825 /Source="Nicolas_upshifts" /id="U2193" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.486513486513487" /psig="0.954045954045954" /xcortree=614 /SigmaFactorBS="ttttaaaacgacttcacaagtacagtcacattttctgTCTTT ATAtttggaaacaggaTGGAATATGATTAAGATGAAttgaacgatattctgcacaatc c" /listShort="S1074" /GFF_Attribute="listLong" CDS 2763890..2764345 /gene="ysnE" /locus_tag="BSU_28330" /old_locus_tag="BSU28330" /EC_number="2.3.1.-" /function="16.5: Explore" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 17555270, 26337367; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative indole acetic acid N-acetyltransferase" /protein_id="NP_390711.1" /db_xref="EnsemblGenomes-Gn:BSU28330" /db_xref="EnsemblGenomes-Tr:CAB14793" /db_xref="GOA:P94562" /db_xref="InterPro:IPR000182" /db_xref="InterPro:IPR016181" /db_xref="PDB:1YX0" /db_xref="SubtiList:BG12336" /db_xref="UniProtKB/Swiss-Prot:P94562" /translation="MHIKIDDLTGRQVVSLVNEHLHSMTLMSPPESIHALGLEKLRGP EITFWSAWEGDELAGCGALKELDTRHGEIKSMRTSASHLRKGVAKQVLQHIIEEAEKR GYERLSLETGSMASFEPARKLYESFGFQYCEPFADYGEDPNSVFMTKKL*" gene 2763890..2764345 /gene="ysnE" /locus_tag="BSU_28330" /old_locus_tag="BSU28330" promotor_-35 2764453..2764459 /Source="Nicolas_upshift_promotors" /id="U2194" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=194 /SigmaFactorBS="cacctttatgatacacgccaatgttttcaatttTGTTTAAtt caaagaacagcGGGAATTACAAACGACATGaacgatatcatgcaaattcataaaggag g" /listShort="ysnF" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2764473..2764491 /Source="Nicolas_upshift_promotors" /id="U2194" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=194 /SigmaFactorBS="cacctttatgatacacgccaatgttttcaatttTGTTTAAtt caaagaacagcGGGAATTACAAACGACATGaacgatatcatgcaaattcataaaggag g" /listShort="ysnF" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2764480 /Source="Nicolas_upshifts" /id="U2194" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=194 /SigmaFactorBS="cacctttatgatacacgccaatgttttcaatttTGTTTAAtt caaagaacagcGGGAATTACAAACGACATGaacgatatcatgcaaattcataaaggag g" /listShort="ysnF" /GFF_Attribute="listLong" CDS 2764529..2765350 /gene="ysnF" /locus_tag="BSU_28340" /old_locus_tag="BSU28340" /function="16.8: Protect" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 11988534, 27464829; Product type ph: phenotype" /codon_start=1 /transl_table=11 /product="putative stress response protein" /protein_id="NP_390712.3" /db_xref="EnsemblGenomes-Gn:BSU28340" /db_xref="EnsemblGenomes-Tr:CAB14794" /db_xref="InterPro:IPR019060" /db_xref="InterPro:IPR025889" /db_xref="SubtiList:BG12337" /db_xref="UniProtKB/Swiss-Prot:P94560" /translation="MKSIVGVYETPQETIAAIEGLLTKGYDSDDISVVTSRRDTDYLE SRTGTEVNQAIDAHQDESESFFDKLKDYFTMDDTATHSKALSDLDIKTDEIDKYQEDL DDGKLLVAVDTDADVIAPIDNGNALSGGFSSTNELDYTTKEEKTMPLREEQLKVDKED VQTGEVEIGKEVKTEKRDMDIPVRHDEIYVERRPVDENKTDAAPVNDSEEIRVPIVEE KLEVTKKPVVTDEVVVGKRTVEENEHISETVKKEEPRLNKEGKVDGLDDDPLNNK*" gene 2764529..2765350 /gene="ysnF" /locus_tag="BSU_28340" /old_locus_tag="BSU28340" downshifts 2765343 /Source="Nicolas_upshifts" /id="D1448" /incds=0 /nref=8 /ntot=77 /MaxReadThrough="2.49244" /MaxDrop="8.12771" /score="22.7277041" /energy="-13.3" /TU="NA" /idTUdmin="U2194" /TUdmin="-21" /isTUend="TRUE" downshifts 2765407 /Source="Nicolas_upshifts" /id="D1449" /incds=0 /nref=1 /ntot=38 /MaxReadThrough="1.26489" /MaxDrop="4.30778" /score="22.7277041" /energy="-13.3" /TU="NA" /idTUdmin="U2194" /TUdmin=43 /isTUend="FALSE" tRNA complement(2765414..2765487) /gene="trnSL-Arg2" /locus_tag="BSU_tRNA_84" /product="tRNA-Arg" /inference="profile:tRNAscan:1.23" /note="transfer RNA-Arg (UCU); Evidence 2a: Function from experimental evidences in other organisms; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene complement(2765414..2765487) /gene="trnSL-Arg2" /locus_tag="BSU_tRNA_84" downshifts complement(2765448) /Source="Nicolas_upshifts" /id="D1450" /incds=0 /nref=34 /ntot=243 /MaxReadThrough="1.54905" /MaxDrop="4.72186" /score="24.0242272" /energy="-13.3" /TU="U2195,U2196" /idTUdmin="U2195" /TUdmin="-31" /isTUend="FALSE" promotor_-10 complement(2765524..2765543) /Source="Nicolas_upshift_promotors" /id="U2195" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.843156843156843" /psig=1 /xcortree=282 /SigmaFactorBS="catgaaaaaaattctaaaaaaccGTTGACTTattattgcatc ccATATATAATAAATCTTGTCGctgatagttaaagcgaaaaacaaaaaaacaaaacgt g" /listShort="trnSL-Arg2" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2765527) /Source="Nicolas_upshifts" /id="U2195" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.843156843156843" /psig=1 /xcortree=282 /SigmaFactorBS="catgaaaaaaattctaaaaaaccGTTGACTTattattgcatc ccATATATAATAAATCTTGTCGctgatagttaaagcgaaaaacaaaaaaacaaaacgt g" /listShort="trnSL-Arg2" /GFF_Attribute="listLong" promotor_-35 complement(2765557..2765564) /Source="Nicolas_upshift_promotors" /id="U2195" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.843156843156843" /psig=1 /xcortree=282 /SigmaFactorBS="catgaaaaaaattctaaaaaaccGTTGACTTattattgcatc ccATATATAATAAATCTTGTCGctgatagttaaagcgaaaaacaaaaaaacaaaacgt g" /listShort="trnSL-Arg2" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2765618..2766127) /gene="ysnB" /locus_tag="BSU_28350" /old_locus_tag="BSU28350" /EC_number="3.1.4.-" /function="16.6: Maintain" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative phosphoesterase" /protein_id="NP_390713.2" /db_xref="EnsemblGenomes-Gn:BSU28350" /db_xref="EnsemblGenomes-Tr:CAB14795" /db_xref="GOA:P94559" /db_xref="InterPro:IPR000979" /db_xref="InterPro:IPR020935" /db_xref="InterPro:IPR024654" /db_xref="InterPro:IPR029052" /db_xref="SubtiList:BG12334" /db_xref="UniProtKB/Swiss-Prot:P94559" /translation="MNVLIISDSHGLEEELQTIAKRHEAEVDLMIHCGDSELETRHPA LEPYAVVKGNCDFAGDFKDELLLTAGSRKILVTHGHLHGIKQTLLNVYYRAEELGADV ICFGHSHIAGSEVLRGKLMINPGSIRLPRVRRTESYAILTLENDAATVRFYDQAGNEI EDLQNRVTL*" gene complement(2765618..2766127) /gene="ysnB" /locus_tag="BSU_28350" /old_locus_tag="BSU28350" downshifts complement(2765635) /Source="Nicolas_upshifts" /id="D1451" /incds=0 /nref=87 /ntot=225 /MaxReadThrough="4.15666" /MaxDrop="5.59323" /score="24.0242272" /energy="-13.3" /TU="U2196,U2197" /idTUdmin="U2197" /TUdmin="-130" /isTUend="FALSE" CDS complement(2766143..2766739) /gene="rdgB" /locus_tag="BSU_28360" /old_locus_tag="BSU28360" /EC_number="3.6.1.66" /function="16.8: Protect" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 16322510, 17090528, 17976651, 18689515, 19943897; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="deoxyinosine/deoxyxanthosine triphosphate pyrophosphatase, promiscuous (subunit A)" /protein_id="NP_390714.1" /db_xref="EnsemblGenomes-Gn:BSU28360" /db_xref="EnsemblGenomes-Tr:CAB14796" /db_xref="GOA:P94558" /db_xref="InterPro:IPR002637" /db_xref="InterPro:IPR020922" /db_xref="InterPro:IPR029001" /db_xref="SubtiList:BG12333" /db_xref="UniProtKB/Swiss-Prot:P94558" /translation="MIIMKEAIIATHNPGKVKEFKEILEPRGYDVKSLAEIGFTEEIE ETGHTFEENAIMKAEAVAKAVNKMVIADDSGLSIDNLGGRPGVYSARYAGEQKDDQAN IEKVLSELKGIEKEQRTARFRCALAVSIPGEETKTVEGHVEGYIAEEPRGEYGFGYDP IFIVKDKDKTMAELTSDEKNKISHRADALKKLSKLLEA*" gene complement(2766143..2766739) /gene="rdgB" /locus_tag="BSU_28360" /old_locus_tag="BSU28360" CDS complement(2766752..2767489) /gene="rph" /locus_tag="BSU_28370" /old_locus_tag="BSU28370" /EC_number="2.7.7.56" /function="16.2: Construct biomass (Anabolism)" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:1624460, 19153445" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1624460, 19153445; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="ribonuclease PH" /protein_id="NP_390715.1" /db_xref="EnsemblGenomes-Gn:BSU28370" /db_xref="EnsemblGenomes-Tr:CAB14797" /db_xref="GOA:P28619" /db_xref="InterPro:IPR001247" /db_xref="InterPro:IPR002381" /db_xref="InterPro:IPR015847" /db_xref="InterPro:IPR018336" /db_xref="InterPro:IPR020568" /db_xref="InterPro:IPR027408" /db_xref="InterPro:IPR036345" /db_xref="PDB:1OYP" /db_xref="PDB:1OYR" /db_xref="PDB:1OYS" /db_xref="SubtiList:BG10357" /db_xref="UniProtKB/Swiss-Prot:P28619" /translation="MRHDGRQHDELRPITFDLDFISHPEGSVLITAGNTKVICNASVE DRVPPFLRGGGKGWITAEYSMLPRATNQRTIRESSKGKISGRTMEIQRLIGRALRAVV DLEKLGERTIWIDCDVIQADGGTRTASITGAFLAMAIAIGKLIKAGTIKTNPITDFLA AISVGIDKEQGILLDLNYEEDSSAEVDMNVIMTGSGRFVELQGTGEEATFSREDLNGL LGLAEKGIQELIDKQKEVLGDSLPELK*" gene complement(2766752..2767489) /gene="rph" /locus_tag="BSU_28370" /old_locus_tag="BSU28370" promotor_-10 complement(2767571..2767590) /Source="Nicolas_upshift_promotors" /id="U2196" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.502497502497502" /psig="0.947052947052947" /xcortree=1453 /SigmaFactorBS="acagaaccggtctccagaccatctcaagtgaatacggGTAGT TtttaaattgggattTTTGATATACTAGGAAGAAAgaggttagcgttccggctgcctc t" /listShort="rph, ysnA, ysnB, trnSL-Arg2" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2767587) /Source="Nicolas_upshifts" /id="U2196" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.502497502497502" /psig="0.947052947052947" /xcortree=1453 /SigmaFactorBS="acagaaccggtctccagaccatctcaagtgaatacggGTAGT TtttaaattgggattTTTGATATACTAGGAAGAAAgaggttagcgttccggctgcctc t" /listShort="rph, ysnA, ysnB, trnSL-Arg2" /GFF_Attribute="listLong" CDS complement(2767600..2768700) /gene="gerM" /locus_tag="BSU_28380" /old_locus_tag="BSU28380" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:14662349, 27381174" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 14662349, 27381174; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="germination (cortex hydrolysis) and sporulation (stage II, multiple polar septa) lytic enzyme" /protein_id="NP_390716.1" /db_xref="EnsemblGenomes-Gn:BSU28380" /db_xref="EnsemblGenomes-Tr:CAB14798" /db_xref="GOA:P39072" /db_xref="InterPro:IPR019606" /db_xref="SubtiList:BG10356" /db_xref="UniProtKB/Swiss-Prot:P39072" /translation="MLKKGPAVIGATCLTSALLLSGCGLFQSDKAAEEIDPPQDVTFV NDEAGANSNTTAAKKTESEKSDTAKADQASSTVMRELYLIDKNGYVVAQTLPLPKSES TAKQALEYLVQGGPVSEILPNGFRAVLPADTTVNVDIKKDGTAIADFSNEFKNYKKED EQKIVQSVTWTLTQFSSIDKVKLRINGHELKEMPVGGTPISDDLSRKDGINLETAGVN DLTATHPLTVYYLAENEDSEYYVPVTKRIDNSEKDDITAAINELAKGPSKVSGLLTDF SEDVKLVSKPKIKDGRVTLDFNQSIFGSADEKTKMISSEVLNSIVLTLTEQPDVKSVS VKVNGKSELVNEKGEKLTEPVSRPSQVNTGSF*" gene complement(2767600..2768700) /gene="gerM" /locus_tag="BSU_28380" /old_locus_tag="BSU28380" promotor_-35 complement(2767605..2767610) /Source="Nicolas_upshift_promotors" /id="U2196" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.502497502497502" /psig="0.947052947052947" /xcortree=1453 /SigmaFactorBS="acagaaccggtctccagaccatctcaagtgaatacggGTAGT TtttaaattgggattTTTGATATACTAGGAAGAAAgaggttagcgttccggctgcctc t" /listShort="rph, ysnA, ysnB, trnSL-Arg2" /GFF_Attribute="listLong" /label="promotor_-35" downshifts complement(2767617) /Source="Nicolas_upshifts" /id="D1452" /incds=0 /nref=2 /ntot=16 /MaxReadThrough="5.80816" /MaxDrop="4.3535" /score="41.5916163" /energy="-13" /TU="U2197" /idTUdmin="U2198" /TUdmin=1209 /isTUend="FALSE" promotor_-10 complement(2768723..2768741) /Source="Nicolas_upshift_promotors" /id="U2197" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=980 /SigmaFactorBS="tatgttgcgggtttttttctgttttgccggaattcttcGGTC TAtttcctaaagaggcTCGTATACATAATAGTACAaacatccttaggagggaaaagta t" /listShort="gerM, rph, ysnA, ysnB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2768739) /Source="Nicolas_upshifts" /id="U2197" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=980 /SigmaFactorBS="tatgttgcgggtttttttctgttttgccggaattcttcGGTC TAtttcctaaagaggcTCGTATACATAATAGTACAaacatccttaggagggaaaagta t" /listShort="gerM, rph, ysnA, ysnB" /GFF_Attribute="listLong" promotor_-35 complement(2768756..2768761) /Source="Nicolas_upshift_promotors" /id="U2197" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=980 /SigmaFactorBS="tatgttgcgggtttttttctgttttgccggaattcttcGGTC TAtttcctaaagaggcTCGTATACATAATAGTACAaacatccttaggagggaaaagta t" /listShort="gerM, rph, ysnA, ysnB" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2768815..2769633) /gene="rcmE" /locus_tag="BSU_28390" /old_locus_tag="BSU28390" /EC_number="5.1.1.3" /function="16.2: Construct biomass (Anabolism)" /function="16.13: Shape" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1c: Function from experimental evidences in the studied genus; PubMedId: 15347750, 17610893, 17720142, 19309142; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="glutamate racemase" /protein_id="NP_390717.2" /db_xref="EnsemblGenomes-Gn:BSU28390" /db_xref="EnsemblGenomes-Tr:CAB14799" /db_xref="GOA:P94556" /db_xref="InterPro:IPR001920" /db_xref="InterPro:IPR004391" /db_xref="InterPro:IPR015942" /db_xref="InterPro:IPR018187" /db_xref="InterPro:IPR033134" /db_xref="PDB:1ZUW" /db_xref="SubtiList:BG11964" /db_xref="UniProtKB/Swiss-Prot:P94556" /translation="MLEQPIGVIDSGVGGLTVAKEIMRQLPKENIIYVGDTKRCPYGP RPEEEVLQYTWELTNYLLENHHIKMLVIACNTATAIALDDIQRSVGIPVVGVIQPGAR AAIKVTDNQHIGVIGTENTIKSNAYEEALLALNPDLKVENLACPLLVPFVESGKFLDK TADEIVKTSLYPLKDTSIDSLILGCTHYPILKEAIQRYMGEHVNIISSGDETAREVST ILSYKGLLNQSPIAPDHQFLTTGARDQFAKIADDWFGHEVGHVECISLQEPIKR*" gene complement(2768815..2769633) /gene="rcmE" /locus_tag="BSU_28390" /old_locus_tag="BSU28390" downshifts complement(2768827) /Source="Nicolas_upshifts" /id="D1453" /incds=0 /nref=230 /ntot=265 /MaxReadThrough="0.9265" /MaxDrop="6.72492" /score="41.5916163" /energy="-13" /TU="NA" /idTUdmin="U2198" /TUdmin="-1" /isTUend="TRUE" CDS complement(2769641..2770081) /gene="ysmB" /locus_tag="BSU_28400" /old_locus_tag="BSU28400" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 26577401; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative transcriptional regulator (mother cell's gene expression during sporulation)" /protein_id="NP_390718.1" /db_xref="EnsemblGenomes-Gn:BSU28400" /db_xref="EnsemblGenomes-Tr:CAB14800" /db_xref="GOA:P97247" /db_xref="InterPro:IPR000835" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG12332" /db_xref="UniProtKB/Swiss-Prot:P97247" /translation="MTSKPLEHVADIEKSLRHIAAIIKQKGREILNQYAITPPQFVGL QWLYELGDMTIGELSGKMYLACSTTTDLIDRMQKNELVERVKDPADRRVVRIHLLPEG ERIIQEVITKRQEYLRDMFESFTDEEIAIFEKSLMKLQHEMKRK*" gene complement(2769641..2770081) /gene="ysmB" /locus_tag="BSU_28400" /old_locus_tag="BSU28400" promotor_-10 complement(2770124..2770143) /Source="Nicolas_upshift_promotors" /id="U2198" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.862137862137862" /psig="0.997002997002997" /xcortree=2513 /SigmaFactorBS="gactaaagtcctctatttctctcctgcgagTCTTGcattttc ttcaaaaaAGAAGGAAAATAGACACGGAacgcttttgtgcgtaagagatccttgagtg a" /listShort="ysmB, racE" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2770133) /Source="Nicolas_upshifts" /id="U2198" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.862137862137862" /psig="0.997002997002997" /xcortree=2513 /SigmaFactorBS="gactaaagtcctctatttctctcctgcgagTCTTGcattttc ttcaaaaaAGAAGGAAAATAGACACGGAacgcttttgtgcgtaagagatccttgagtg a" /listShort="ysmB, racE" /GFF_Attribute="listLong" S_feature complement(2770135..2770277) /Source="Nicolas_S_feature" /locus_tag="new_2904537_2904679_c" /HighExp="BT, B36, S6, S8, S7, B60, Pyr, G/S, Lbtran, Mt0" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.121047" /TUshortSig="SigK, SigA" /TUshortPSig="1, 0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S1075" promotor_-35 complement(2770159..2770163) /Source="Nicolas_upshift_promotors" /id="U2198" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.862137862137862" /psig="0.997002997002997" /xcortree=2513 /SigmaFactorBS="gactaaagtcctctatttctctcctgcgagTCTTGcattttc ttcaaaaaAGAAGGAAAATAGACACGGAacgcttttgtgcgtaagagatccttgagtg a" /listShort="ysmB, racE" /GFF_Attribute="listLong" /label="promotor_-35" downshifts complement(2770322) /Source="Nicolas_upshifts" /id="D1454" /incds=0 /nref=2 /ntot=16 /MaxReadThrough="6.16749" /MaxDrop="4.6532" /score="20.9204638" /energy="-10.8" /TU="U2200,U2202" /idTUdmin="U2202" /TUdmin="-176" /isTUend="FALSE" CDS complement(2770325..2770549) /gene="gerE" /locus_tag="BSU_28410" /old_locus_tag="BSU28410" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:11243786, 11418558, 11741866, 14702409, 17172339, 20435725, 21670523, 26790838" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11243786, 11418558, 11741866, 14702409, 17172339, 20435725, 21670523, 26790838; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="transcriptional regulator required for the expression of late spore coat genes" /protein_id="NP_390719.2" /db_xref="EnsemblGenomes-Gn:BSU28410" /db_xref="EnsemblGenomes-Tr:CAB14801" /db_xref="GOA:P11470" /db_xref="InterPro:IPR000792" /db_xref="InterPro:IPR016032" /db_xref="InterPro:IPR036388" /db_xref="PDB:1FSE" /db_xref="SubtiList:BG10355" /db_xref="UniProtKB/Swiss-Prot:P11470" /translation="MKEKEFQSKPLLTKREREVFELLVQDKTTKEIASELFISEKTVR NHISNAMQKLGVKGRSQAVVELLRMGELEL*" gene complement(2770325..2770549) /gene="gerE" /locus_tag="BSU_28410" /old_locus_tag="BSU28410" upshifts 2770598 /Source="Nicolas_upshifts" /id="U2199" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.481518481518482" /psig="0.838161838161838" /xcortree=697 /SigmaFactorBS="tttctccttcaagtattgtaaccctccttgctaaggtgagag cgaatcagaaacgaatgggtTTTGATATAGTCGAGATATcatatgtaagaagggcgca g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" misc_feature 2770600..2770618 /Source="Nicolas_upshift_promotors" /id="U2199" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.481518481518482" /psig="0.838161838161838" /xcortree=697 /SigmaFactorBS="tttctccttcaagtattgtaaccctccttgctaaggtgagag cgaatcagaaacgaatgggtTTTGATATAGTCGAGATATcatatgtaagaagggcgca g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" promotor_-10 complement(2770607..2770626) /Source="Nicolas_upshift_promotors" /id="U2200" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1352 /SigmaFactorBS="aaacgcttcttcatacacgataaactaattatcttgtaAACG TCACCTcctgcgcccttctTACATATGATATCTCGACTAtatcaaaacccattcgttt c" /listShort="gerE, S1075, ysmB, racE" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2770627) /Source="Nicolas_upshifts" /id="U2200" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1352 /SigmaFactorBS="aaacgcttcttcatacacgataaactaattatcttgtaAACG TCACCTcctgcgcccttctTACATATGATATCTCGACTAtatcaaaacccattcgttt c" /listShort="gerE, S1075, ysmB, racE" /GFF_Attribute="listLong" promotor_-35 complement(2770640..2770649) /Source="Nicolas_upshift_promotors" /id="U2200" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1352 /SigmaFactorBS="aaacgcttcttcatacacgataaactaattatcttgtaAACG TCACCTcctgcgcccttctTACATATGATATCTCGACTAtatcaaaacccattcgttt c" /listShort="gerE, S1075, ysmB, racE" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2770665..2771108) /gene="ysmA" /locus_tag="BSU_28420" /old_locus_tag="BSU28420" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_390720.1" /db_xref="EnsemblGenomes-Gn:BSU28420" /db_xref="EnsemblGenomes-Tr:CAB14802" /db_xref="InterPro:IPR006683" /db_xref="InterPro:IPR029069" /db_xref="SubtiList:BG10354" /db_xref="UniProtKB/Swiss-Prot:P11469" /translation="MKLPAYIDMPFQEWKTSFSFFNKVSVRFSETDMFGHMNNVTPFI YFEEVRISYFKKLNMMSENKQTMTVVASQQCDYLRQVMPYEELRIYVKTSAVGSSSLT LHYLGENLEGEPCFTGAVVMVQVSKESGKAVSWTDEEKETLLHTR*" gene complement(2770665..2771108) /gene="ysmA" /locus_tag="BSU_28420" /old_locus_tag="BSU28420" CDS complement(2771169..2771930) /gene="sdhB" /locus_tag="BSU_28430" /old_locus_tag="BSU28430" /EC_number="1.3.5.1" /function="16.10: Respire" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:11803018, 1707123, 22720735, 22389480, 22790590" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11803018, 1707123, 22720735, 22389480, 22790590; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="succinate dehydrogenase (iron-sulfur protein)" /protein_id="NP_390721.1" /db_xref="EnsemblGenomes-Gn:BSU28430" /db_xref="EnsemblGenomes-Tr:CAB14803" /db_xref="GOA:P08066" /db_xref="InterPro:IPR004489" /db_xref="InterPro:IPR009051" /db_xref="InterPro:IPR012675" /db_xref="InterPro:IPR017896" /db_xref="InterPro:IPR017900" /db_xref="InterPro:IPR025192" /db_xref="InterPro:IPR036010" /db_xref="SubtiList:BG10353" /db_xref="UniProtKB/Swiss-Prot:P08066" /translation="MSEQKTIRFIITRQDTADSTPYDEEFEIPYRPNLNVISALMEIR RNPVNVKGEKTTPVTWDMNCLEEVCGACSMVINGKPRQSCTALIDQLEQPIRLKPMKT FPVVRDLQVDRSRMFDSLKKVKAWIPIDGTYDLGPGPRMPEKRRQWAYELSKCMTCGV CLEACPNVNSKSKFMGPAPMSQVRLFNAHPTGAMNKSERLEALMDEGGLADCGNSQNC VQSCPKGIPLTTSIAALNRDTNLQAFRNFFGSDRV*" gene complement(2771169..2771930) /gene="sdhB" /locus_tag="BSU_28430" /old_locus_tag="BSU28430" downshifts complement(2771177) /Source="Nicolas_upshifts" /id="D1455" /incds=0 /nref=61 /ntot=257 /MaxReadThrough="5.46426" /MaxDrop="4.6864" /score="20.9204638" /energy="-10.8" /TU="U2202" /idTUdmin="U2205" /TUdmin=1 /isTUend="TRUE" CDS complement(2771933..2773693) /gene="sdhA" /locus_tag="BSU_28440" /old_locus_tag="BSU28440" /EC_number="1.3.5.1" /function="16.10: Respire" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:11803018, 1707123, 18535631, 22389480, 22790590" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11803018, 1707123, 18535631, 22389480, 22790590; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="succinate dehydrogenase (flavoprotein subunit)" /protein_id="NP_390722.2" /db_xref="EnsemblGenomes-Gn:BSU28440" /db_xref="EnsemblGenomes-Tr:CAB14804" /db_xref="GOA:P08065" /db_xref="InterPro:IPR003952" /db_xref="InterPro:IPR003953" /db_xref="InterPro:IPR011280" /db_xref="InterPro:IPR015939" /db_xref="InterPro:IPR027477" /db_xref="InterPro:IPR036188" /db_xref="InterPro:IPR037099" /db_xref="SubtiList:BG10352" /db_xref="UniProtKB/Swiss-Prot:P08065" /translation="MSQSSIIVVGGGLAGLMATIKAAESGMAVKLFSIVPVKRSHSVC AQGGINGAVNTKGEGDSPWEHFDDTVYGGDFLANQPPVKAMCEAAPSIIHLLDRMGVM FNRTPEGLLDFRRFGGTQHHRTAYAGATTGQQLLYALDEQVRRYEVAGLVTKYEGWEF LGAVLDDDRTCRGIVAQNLTNMQIESFRSDAVIMATGGPGIIFGKSTNSMINTGSAAS IVYQQGAYYANGEFIQIHPTAIPGDDKLRLMSESARGEGGRVWTYKDGKPWYFLEEKY PAYGNLVPRDIATREIFDVCVNQKLGINGENMVYLDLSHKDPKELDIKLGGIIEIYEK FMGDDPRKLPMKIFPAVHYSMGGLWVDYDQMTNIPGLFAAGECDYSMHGGNRLGANSL LSAIYGGMVAGPNAVKYVNGLESSAEDMSSSLFDAHVKKEEEKWADIMSMDGTENAYV LHKELGEWMTANVTVVRHNDKLLKTDDKIQELMERFKKININDTTKWSNQGAMFTRQF SNMLQLARVITLGAYNRNESRGAHYKPDYPERNDDEWLKTTMAKHVSPYEAPEFEYQD VDVSLITPRKRDYSKKKVAK*" gene complement(2771933..2773693) /gene="sdhA" /locus_tag="BSU_28440" /old_locus_tag="BSU28440" CDS complement(2773727..2774335) /gene="sdhC" /locus_tag="BSU_28450" /old_locus_tag="BSU28450" /EC_number="1.3.5.1" /function="16.2: Construct biomass (Anabolism)" /function="16.10: Respire" /experiment="publication(s) with functional evidences, PMID:11803018, 15849754, 16850406, 1707123, 18535631, 22389480, 22389480" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11803018, 15849754, 16850406, 1707123, 18535631, 22389480, 22389480; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="succinate dehydrogenase (cytochrome b558 subunit)" /protein_id="NP_390723.1" /db_xref="EnsemblGenomes-Gn:BSU28450" /db_xref="EnsemblGenomes-Tr:CAB14805" /db_xref="GOA:P08064" /db_xref="InterPro:IPR000701" /db_xref="InterPro:IPR011138" /db_xref="InterPro:IPR016002" /db_xref="InterPro:IPR034804" /db_xref="SubtiList:BG10351" /db_xref="UniProtKB/Swiss-Prot:P08064" /translation="MSGNREFYFRRLHSLLGVIPVGIFLIQHLVVNQFAARGAEAFNS AAHFMDSLPFRYALEIFIIFLPLIYHAVYGVYIAFTAKNNAGQYSYMRNWLFVLQRVT GIITLIFVSWHVWETRIAAQMGAEVNFDMMANILSSPAMLGFYIVGVLSTIFHFSNGL WSFAVTWGITVTPRSQRISTYVTLIIFVALSYVGLKAIFAFV*" gene complement(2773727..2774335) /gene="sdhC" /locus_tag="BSU_28450" /old_locus_tag="BSU28450" promotor_-35 2774105..2774112 /Source="Nicolas_upshift_promotors" /id="U2201" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.545454545454545" /psig=1 /xcortree=646 /SigmaFactorBS="tagctgtattgaccggcgttatttttcgcagtaaacgcTATG TACAcaccataaactgCATGATAAATTAATGGTAAGaagataataaaaatttccaagg c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2774125..2774144 /Source="Nicolas_upshift_promotors" /id="U2201" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.545454545454545" /psig=1 /xcortree=646 /SigmaFactorBS="tagctgtattgaccggcgttatttttcgcagtaaacgcTATG TACAcaccataaactgCATGATAAATTAATGGTAAGaagataataaaaatttccaagg c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2774127 /Source="Nicolas_upshifts" /id="U2201" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.545454545454545" /psig=1 /xcortree=646 /SigmaFactorBS="tagctgtattgaccggcgttatttttcgcagtaaacgcTATG TACAcaccataaactgCATGATAAATTAATGGTAAGaagataataaaaatttccaagg c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" S_feature complement(2774336..2774431) /Source="Nicolas_S_feature" /locus_tag="new_2908738_2908833_c" /HighExp="Lbtran, dia5, Mt0, T0.30H, T1.0H, M0t90, M40t90, T0.0H, Glucon, dia0" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.78844099999999995" /TUshortSig="SigA, SigA" /TUshortPSig="0.999, 1" /TUlongSig="SigA" /TUlongPSig=1 /label="S1076" promotor_-10 complement(2774421..2774440) /Source="Nicolas_upshift_promotors" /id="U2202" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.766233766233766" /psig="0.999000999001" /xcortree=2226 /SigmaFactorBS="tcggaaaattataatttatgtacgcgtttTCTTGACGccctt ttgagggagGAGTAAAATGAAATTGTCAAtaaatcttaataaagtgcttacaattgaa a" /listShort="S1076, sdhC, sdhA, sdhB, ysmA, gerE, S1075" /listLong="ysmB, racE" /label="promotor_-10" upshifts complement(2774431) /Source="Nicolas_upshifts" /id="U2202" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.766233766233766" /psig="0.999000999001" /xcortree=2226 /SigmaFactorBS="tcggaaaattataatttatgtacgcgtttTCTTGACGccctt ttgagggagGAGTAAAATGAAATTGTCAAtaaatcttaataaagtgcttacaattgaa a" /listShort="S1076, sdhC, sdhA, sdhB, ysmA, gerE, S1075" /listLong="ysmB, racE" S_feature complement(2774433..2775054) /Source="Nicolas_S_feature" /locus_tag="new_2908835_2909456_c" /HighExp="MG 120, B36, UNK1, Fru, MG 150, BMM, Gly, Glucon, Glu, GM-0.1" /AntisenseName="yslB" /AntisenseCor="-0.44143968421748903" /AntisenseRegPval="-13.5" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="SigA" /TUlongPSig=1 /label="S1077" promotor_-35 complement(2774455..2774462) /Source="Nicolas_upshift_promotors" /id="U2202" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.766233766233766" /psig="0.999000999001" /xcortree=2226 /SigmaFactorBS="tcggaaaattataatttatgtacgcgtttTCTTGACGccctt ttgagggagGAGTAAAATGAAATTGTCAAtaaatcttaataaagtgcttacaattgaa a" /listShort="S1076, sdhC, sdhA, sdhB, ysmA, gerE, S1075" /listLong="ysmB, racE" /label="promotor_-35" promotor_-35 2774570..2774574 /Source="Nicolas_upshift_promotors" /id="U2203" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.612387612387612" /psig="0.995004995004995" /xcortree=2758 /SigmaFactorBS="cttaatttttcataagaattacaggatcatTCTGTaatcctc ccccctgttTGAGCTATAATATACGCAGGagagaggggagacagatatgaagtctaaa t" /listShort="yslB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_no_box 2774584..2774684 /Source="Nicolas_upshift_promotors" /id="U2204" /multdbtbs="-" /comp="M21" /sig="Sig-" /pcomp="0.631368631368631" /psig="0.024975024975025" /xcortree=1731 /SigmaFactorBS="ccctgtttgagctataatatacgcaggagagaggggagacag atatgaagtctaaatttgaagcatctattgacaacctaaaagaaattgaaatgaacgc t" /listShort="yslB" /GFF_Attribute="listLong" /label="promotor_no_box" promotor_-10 2774591..2774610 /Source="Nicolas_upshift_promotors" /id="U2203" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.612387612387612" /psig="0.995004995004995" /xcortree=2758 /SigmaFactorBS="cttaatttttcataagaattacaggatcatTCTGTaatcctc ccccctgttTGAGCTATAATATACGCAGGagagaggggagacagatatgaagtctaaa t" /listShort="yslB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2774600 /Source="Nicolas_upshifts" /id="U2203" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.612387612387612" /psig="0.995004995004995" /xcortree=2758 /SigmaFactorBS="cttaatttttcataagaattacaggatcatTCTGTaatcctc ccccctgttTGAGCTATAATATACGCAGGagagaggggagacagatatgaagtctaaa t" /listShort="yslB" /GFF_Attribute="listLong" CDS 2774628..2775074 /gene="yslB" /locus_tag="BSU_28460" /old_locus_tag="BSU28460" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_390724.1" /db_xref="EnsemblGenomes-Gn:BSU28460" /db_xref="EnsemblGenomes-Tr:CAB14806" /db_xref="InterPro:IPR019642" /db_xref="InterPro:IPR024096" /db_xref="PDB:3NJC" /db_xref="SubtiList:BG11236" /db_xref="UniProtKB/Swiss-Prot:P42955" /translation="MKSKFEASIDNLKEIEMNAYAYELIREIVLPDMLGQDYSSMMYW AGKHLARKFPLESWEEFPAFFEEAGWGTLTNVSAKKQELEFELEGPIISNRLKHQKEP CFQLEAGFIAEQIQLMNDQIAESYEQVKKRADKVVLTVKWDMKDPV*" gene 2774628..2775074 /gene="yslB" /locus_tag="BSU_28460" /old_locus_tag="BSU28460" upshifts 2774644 /Source="Nicolas_upshifts" /id="U2204" /multdbtbs="-" /comp="M21" /sig="Sig-" /pcomp="0.631368631368631" /psig="0.024975024975025" /xcortree=1731 /SigmaFactorBS="ccctgtttgagctataatatacgcaggagagaggggagacag atatgaagtctaaatttgaagcatctattgacaacctaaaagaaattgaaatgaacgc t" /listShort="yslB" /GFF_Attribute="listLong" downshifts 2775062 /Source="Nicolas_upshifts" /id="D1456" /incds=0 /nref=217 /ntot=255 /MaxReadThrough="2.21897" /MaxDrop="6.5759" /score="4.74486914" /energy="-10.8" /TU="NA" /idTUdmin="U2203" /TUdmin=0 /isTUend="TRUE" downshifts complement(2775100) /Source="Nicolas_upshifts" /id="D1457" /incds=0 /nref=8 /ntot=160 /MaxReadThrough="5.89867" /MaxDrop="4.19639" /score="2.38159916" /energy="-10.8" /TU="U2205" /idTUdmin="U2206" /TUdmin=1270 /isTUend="FALSE" CDS complement(2775118..2776344) /gene="lysCA" /locus_tag="BSU_28470" /old_locus_tag="BSU28470" /EC_number="2.7.2.4" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:2981221, 2981222, 14597663, 1980002, 8757727, 9851048" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 2981221, 2981222, 14597663, 1980002, 8757727, 9851048; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="aspartokinase II alpha subunit (aa 1->408)" /protein_id="NP_390725.1" /db_xref="EnsemblGenomes-Gn:BSU28470" /db_xref="EnsemblGenomes-Tr:CAB14807" /db_xref="GOA:P08495" /db_xref="InterPro:IPR001048" /db_xref="InterPro:IPR001341" /db_xref="InterPro:IPR002912" /db_xref="InterPro:IPR005260" /db_xref="InterPro:IPR018042" /db_xref="InterPro:IPR027795" /db_xref="InterPro:IPR036393" /db_xref="SubtiList:BG10350" /db_xref="UniProtKB/Swiss-Prot:P08495" /translation="MGLIVQKFGGTSVGSVEKIQNAANRAIAEKQKGHQVVVVVSAMG KSTDELVSLAKAISDQPSKREMDMLLATGEQVTISLLSMALQEKGYDAVSYTGWQAGI RTEAIHGNARITDIDTSVLADQLEKGKIVIVAGFQGMTEDCEITTLGRGGSDTTAVAL AAALKADKCDIYTDVPGVFTTDPRYVKSARKLEGISYDEMLELANLGAGVLHPRAVEF AKNYQVPLEVRSSTETEAGTLIEEESSMEQNLIVRGIAFEDQITRVTIYGLTSGLTTL STIFTTLAKRNINVDIIIQTQAEDKTGISFSVKTEDADQTVAVLEEYKDALEFEKIET ESKLAKVSIVGSGMVSNPGVAAEMFAVLAQKNILIKMVSTSEIKVSTVVSENDMVKAV ESLHDAFELSKHPSAV*" CDS complement(2775118..2775609) /gene="lysCB" /locus_tag="BSU_28475" /old_locus_tag="BSU28475" /EC_number="2.7.2.4" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:1980002, 2981221, 2981222, 8757727, 9851048, 14597663" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1980002, 2981221, 2981222, 8757727, 9851048, 14597663; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="aspartokinase II beta subunit (aa 246->408)" /protein_id="YP_009513994.1" /translation="MEQNLIVRGIAFEDQITRVTIYGLTSGLTTLSTIFTTLAKRNIN VDIIIQTQAEDKTGISFSVKTEDADQTVAVLEEYKDALEFEKIETESKLAKVSIVGSG MVSNPGVAAEMFAVLAQKNILIKMVSTSEIKVSTVVSENDMVKAVESLHDAFELSKHP SAV*" gene complement(2775118..2776344) /gene="lysCA" /locus_tag="BSU_28470" /old_locus_tag="BSU28470" gene complement(2775118..2775609) /gene="lysCB" /locus_tag="BSU_28475" /old_locus_tag="BSU28475" downshifts complement(2776458) /Source="Nicolas_upshifts" /id="D1458" /incds=0 /nref=1 /ntot=22 /MaxReadThrough="7.23315" /MaxDrop="4.15833" /score="31.7469619" /energy="-13.5" /TU="U2205,U2206" /idTUdmin="U2207" /TUdmin=44 /isTUend="FALSE" misc_RNA complement(2776470..2776649) /gene="kswC" /locus_tag="BSU_misc_RNA_46" /product="lysine riboswitch" /experiment="publication(s) with functional evidences, PMID:14523230, 14597663, 14627808, 21169337, 22416067" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 14523230, 14597663, 14627808, 21169337, 22416067; Product type n: RNA" gene complement(2776470..2776649) /gene="kswC" /locus_tag="BSU_misc_RNA_46" downshifts complement(2776502) /Source="Nicolas_upshifts" /id="D1459" /incds=0 /nref=22 /ntot=132 /MaxReadThrough="7.09997" /MaxDrop="4.61976" /score="31.7469619" /energy="-13.5" /TU="U2205,U2206" /idTUdmin="U2207" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(2776674..2776693) /Source="Nicolas_upshift_promotors" /id="U2205" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.472527472527473" /psig=1 /xcortree=3002 /SigmaFactorBS="gctcctttacgacaaattgcaaaaataaTGTTGTCCttttaa ataagaTCTGATAAAATGTGAACTAAtttcatagttagatcgtgttatatggtgaaga t" /listShort="NA, lysC, S1077, S1076, sdhC, sdhA, sdhB" /listLong="ysmA, gerE" /label="promotor_-10" upshifts complement(2776681) /Source="Nicolas_upshifts" /id="U2205" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.472527472527473" /psig=1 /xcortree=3002 /SigmaFactorBS="gctcctttacgacaaattgcaaaaataaTGTTGTCCttttaa ataagaTCTGATAAAATGTGAACTAAtttcatagttagatcgtgttatatggtgaaga t" /listShort="NA, lysC, S1077, S1076, sdhC, sdhA, sdhB" /listLong="ysmA, gerE" promotor_-35 complement(2776706..2776713) /Source="Nicolas_upshift_promotors" /id="U2205" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.472527472527473" /psig=1 /xcortree=3002 /SigmaFactorBS="gctcctttacgacaaattgcaaaaataaTGTTGTCCttttaa ataagaTCTGATAAAATGTGAACTAAtttcatagttagatcgtgttatatggtgaaga t" /listShort="NA, lysC, S1077, S1076, sdhC, sdhA, sdhB" /listLong="ysmA, gerE" /label="promotor_-35" CDS complement(2776714..2778486) /gene="uvrC" /locus_tag="BSU_28490" /old_locus_tag="BSU28490" /EC_number="4.1.99.3" /function="16.6: Maintain" /function="16.9: Replicate" /experiment="publication(s) with functional evidences, PMID:8655545, 16267290, 16426634, 25713353" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8655545, 16267290, 16426634, 25713353; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="excinuclease ABC (subunit C)" /protein_id="NP_390727.2" /db_xref="EnsemblGenomes-Gn:BSU28490" /db_xref="EnsemblGenomes-Tr:CAB14809" /db_xref="GOA:P14951" /db_xref="InterPro:IPR000305" /db_xref="InterPro:IPR001162" /db_xref="InterPro:IPR001943" /db_xref="InterPro:IPR004791" /db_xref="InterPro:IPR010994" /db_xref="InterPro:IPR035901" /db_xref="InterPro:IPR036876" /db_xref="SubtiList:BG10349" /db_xref="UniProtKB/Swiss-Prot:P14951" /translation="MNKQLKEKLALLPDQPGCYLMKDRQQTVIYVGKAKVLKNRVRSY FTGSHDAKTQRLVTEIEDFEYIVTSSNLEALILEMNLIKKHDPKYNVMLKDDKTYPFI KLTHERHPRLIVTRNVKKDKGRYFGPYPNVQAARETKKLLDRLYPLRKCSKLPDRVCL YYHLGQCLAPCVKDISEETNRELVESITRFLRGGYNEVKKELEEKMHEAAENLEFERA KELRDQIAHIESTMEKQKMTMNDLVDRDVFAYAYDKGWMCVQVFFIRQGKLIERDVSM FPLYQEADEEFLTFIGQFYSKNNHFLPKEILVPDSIDQSMIEQLLETNVHQPKKGPKK ELLMLAHKNAKIALKEKFSLIERDEERSIGAVQKLGEALNIYTPHRIEAFDNSNIQGT NPVSAMIVFIDGKPYKKEYRKYKIKTVTGPDDYGSMREVVRRRYTRVLRENLPLPDLI IIDGGKGQINAARDVIENELGLDIPIAGLAKDEKHRTSNLLIGDPLEVAYLERNSQEF YLLQRIQDEVHRFAISFHRQIRGKSAFQSVLDDIPGIGEKRKKMLLKHFGSVKKMKEA SLEDIKKAGVPAAAAQLLYDKLQK*" gene complement(2776714..2778486) /gene="uvrC" /locus_tag="BSU_28490" /old_locus_tag="BSU28490" promotor_-10 complement(2778513..2778532) /Source="Nicolas_upshift_promotors" /id="U2206" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.63936063936064" /psig=1 /xcortree=2092 /SigmaFactorBS="tgagggatcgctttttttattcgccaattgtgaaCCATAGAG aaaaacaaacgttCGTGTTAAACTGGAAATAAAggattaaacataaggaagggtaaca t" /listShort="uvrC, NA" /listLong="lysC, S1077, S1076, sdhC, sdhA, sdhB, ysmA" /label="promotor_-10" upshifts complement(2778527) /Source="Nicolas_upshifts" /id="U2206" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.63936063936064" /psig=1 /xcortree=2092 /SigmaFactorBS="tgagggatcgctttttttattcgccaattgtgaaCCATAGAG aaaaacaaacgttCGTGTTAAACTGGAAATAAAggattaaacataaggaagggtaaca t" /listShort="uvrC, NA" /listLong="lysC, S1077, S1076, sdhC, sdhA, sdhB, ysmA" promotor_-35 complement(2778546..2778553) /Source="Nicolas_upshift_promotors" /id="U2206" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.63936063936064" /psig=1 /xcortree=2092 /SigmaFactorBS="tgagggatcgctttttttattcgccaattgtgaaCCATAGAG aaaaacaaacgttCGTGTTAAACTGGAAATAAAggattaaacataaggaagggtaaca t" /listShort="uvrC, NA" /listLong="lysC, S1077, S1076, sdhC, sdhA, sdhB, ysmA" /label="promotor_-35" downshifts complement(2778616) /Source="Nicolas_upshifts" /id="D1460" /incds=0 /nref=237 /ntot=268 /MaxReadThrough="4.77689" /MaxDrop="6.41061" /score="23.4086154" /energy="-10.5" /TU="U2207,U2208" /idTUdmin="U2209" /TUdmin=373 /isTUend="FALSE" CDS complement(2778622..2778936) /gene="trxA" /locus_tag="BSU_28500" /old_locus_tag="BSU28500" /function="16.6: Maintain" /function="16.8: Protect" /function="16.2: Construct biomass (Anabolism)" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:9537387, 12682299, 1459769, 15937154, 17303556, 18455736, 18601268" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9537387, 12682299, 1459769, 15937154, 17303556, 18455736, 18601268; Product type c: carrier" /codon_start=1 /transl_table=11 /product="thioredoxin" /protein_id="NP_390728.1" /db_xref="EnsemblGenomes-Gn:BSU28500" /db_xref="EnsemblGenomes-Tr:CAB14810" /db_xref="GOA:P14949" /db_xref="InterPro:IPR005746" /db_xref="InterPro:IPR013766" /db_xref="InterPro:IPR017937" /db_xref="InterPro:IPR036249" /db_xref="PDB:2GZY" /db_xref="PDB:2GZZ" /db_xref="PDB:2IPA" /db_xref="PDB:2VOC" /db_xref="SubtiList:BG10348" /db_xref="UniProtKB/Swiss-Prot:P14949" /translation="MAIVKATDQSFSAETSEGVVLADFWAPWCGPCKMIAPVLEELDQ EMGDKLKIVKIDVDENQETAGKYGVMSIPTLLVLKDGEVVETSVGFKPKEALQELVNK HL*" gene complement(2778622..2778936) /gene="trxA" /locus_tag="BSU_28500" /old_locus_tag="BSU28500" promotor_-10 complement(2778962..2778981) /Source="Nicolas_upshift_promotors" /id="U2207" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.496503496503497" /psig="0.995004995004995" /xcortree=1940 /SigmaFactorBS="gctgtgatcaggaaaaaataatttgtaagcattaaaaTAGcg tgaacgaatgggaGATGCTATACTAAAAATCATcatttcacattggaggaattcaata a" /listShort="trxA, uvrC, NA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2778976) /Source="Nicolas_upshifts" /id="U2207" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.496503496503497" /psig="0.995004995004995" /xcortree=1940 /SigmaFactorBS="gctgtgatcaggaaaaaataatttgtaagcattaaaaTAGcg tgaacgaatgggaGATGCTATACTAAAAATCATcatttcacattggaggaattcaata a" /listShort="trxA, uvrC, NA" /GFF_Attribute="listLong" S_feature complement(2778978..2779187) /Source="Nicolas_S_feature" /locus_tag="new_2913380_2913589_c" /HighExp="Etha, Salt, Gly, Sw, M9-stat, LPhT, BC, B60, S5, LoTm" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.99984399999999996" /TUshortSig="SigB, SigA" /TUshortPSig="0.991, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S1078" promotor_-35 complement(2778997..2778999) /Source="Nicolas_upshift_promotors" /id="U2207" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.496503496503497" /psig="0.995004995004995" /xcortree=1940 /SigmaFactorBS="gctgtgatcaggaaaaaataatttgtaagcattaaaaTAGcg tgaacgaatgggaGATGCTATACTAAAAATCATcatttcacattggaggaattcaata a" /listShort="trxA, uvrC, NA" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2779081..2779191) /locus_tag="BSU_28509" /old_locus_tag="BSU28509" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /pseudo /codon_start=1 /transl_table=11 /product="CDS C-terminal fragment" /db_xref="PSEUDO:SOX90589.1" /translation="MVKYMTVKRRCDLMLRTILMIIGAIVVIGAIIRFVF*" gene complement(2779081..2779191) /locus_tag="BSU_28509" /old_locus_tag="BSU28509" /pseudo promotor_-10 complement(2779177..2779195) /Source="Nicolas_upshift_promotors" /id="U2208" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp="0.99100899100899" /psig="0.99100899100899" /xcortree=165 /SigmaFactorBS="cgccggagcttcatgccggcgctctttttcaGGTTTTAaaac agctccggcaGGGCATGGTAAAGTACATGacagtgaagaggagatgtgatcttatgct t" /listShort="S1078, trxA, uvrC" /listLong="NA" /label="promotor_-10" upshifts complement(2779187) /Source="Nicolas_upshifts" /id="U2208" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp="0.99100899100899" /psig="0.99100899100899" /xcortree=165 /SigmaFactorBS="cgccggagcttcatgccggcgctctttttcaGGTTTTAaaac agctccggcaGGGCATGGTAAAGTACATGacagtgaagaggagatgtgatcttatgct t" /listShort="S1078, trxA, uvrC" /listLong="NA" promotor_-35 complement(2779210..2779216) /Source="Nicolas_upshift_promotors" /id="U2208" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp="0.99100899100899" /psig="0.99100899100899" /xcortree=165 /SigmaFactorBS="cgccggagcttcatgccggcgctctttttcaGGTTTTAaaac agctccggcaGGGCATGGTAAAGTACATGacagtgaagaggagatgtgatcttatgct t" /listShort="S1078, trxA, uvrC" /listLong="NA" /label="promotor_-35" CDS complement(2779259..2780746) /gene="abfB" /locus_tag="BSU_28510" /old_locus_tag="BSU28510" /EC_number="3.2.1.55" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:14973026, 17827291, 18757805" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 14973026, 17827291, 18757805; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="exo-alpha-L-arabinofuranosidase" /protein_id="NP_390729.2" /db_xref="EnsemblGenomes-Gn:BSU28510" /db_xref="EnsemblGenomes-Tr:CAB14811" /db_xref="GOA:P94552" /db_xref="InterPro:IPR010720" /db_xref="InterPro:IPR017853" /db_xref="SubtiList:BG11985" /db_xref="UniProtKB/Swiss-Prot:P94552" /translation="MSEHQAVIQTDIAKGTINKNIYGHFAEHLGRGIYEGIWVGTDSD IPNINGIRKDVLEALKQLHIPVLRWPGGCFADEYHWANGVGDRKTMLNTHWGGTIESN EFGTHEFMMLCELLECEPYICGNVGSGTVQEMSEWIEYMTFEEGTPMSDWRKQNGREE PWKLKYFGVGNENWGCGGNMHPEYYADLYRRFQTYVRNYSGNDIYKIAGGANVDDFNW TDVLMKKAAGLMDGLSLHYYTIPGDFWKGKGSATEFTEDEWFITMKKAKYIDELIQKH GTIMDRYDPEQRVGLIIDEWGTWFDPEPGTNPGFLYQQNTIRDALVAASHFHIFHQHC RRVQMANIAQTVNVLQAMILTEGERMLLTPTYHVFNMFKVHQDASLLATETMSADYEW NGETLPQISISASKQAEGDINITICNIDHQNKAEAEIELRGLHKAADHSGVILTAEKM NAHNTFDDPHHVKPESFRQYTLSKNKLKVKLPPMSVVLLTLRADS*" gene complement(2779259..2780746) /gene="abfB" /locus_tag="BSU_28510" /old_locus_tag="BSU28510" S_feature complement(2780747..2780859) /Source="Nicolas_S_feature" /locus_tag="new_2915149_2915261_c" /HighExp="T0.30H, M40t90, M0t90, BC, M9-stat, T1.30H, T1.0H, T2.0H, T2.30H, T3.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1079" promotor_-10 complement(2780840..2780859) /Source="Nicolas_upshift_promotors" /id="U2209" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.903096903096903" /psig=1 /xcortree=367 /SigmaFactorBS="aaatacatacgtacaaatataaaaacaatagaaaatgtCGTT GACAtgtacgaacatataTAATATGGTTACTTTAAAAGcgcttacattcatgctgact c" /listShort="S1079, xsa, S1078" /listLong="trxA" /label="promotor_-10" upshifts complement(2780859) /Source="Nicolas_upshifts" /id="U2209" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.903096903096903" /psig=1 /xcortree=367 /SigmaFactorBS="aaatacatacgtacaaatataaaaacaatagaaaatgtCGTT GACAtgtacgaacatataTAATATGGTTACTTTAAAAGcgcttacattcatgctgact c" /listShort="S1079, xsa, S1078" /listLong="trxA" promotor_-35 complement(2780874..2780881) /Source="Nicolas_upshift_promotors" /id="U2209" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.903096903096903" /psig=1 /xcortree=367 /SigmaFactorBS="aaatacatacgtacaaatataaaaacaatagaaaatgtCGTT GACAtgtacgaacatataTAATATGGTTACTTTAAAAGcgcttacattcatgctgact c" /listShort="S1079, xsa, S1078" /listLong="trxA" /label="promotor_-35" CDS complement(2780963..2781940) /gene="etfA" /locus_tag="BSU_28520" /old_locus_tag="BSU28520" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:17189250, 20059546, 21398533" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 17189250, 20059546, 21398533; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="electron transfer flavoprotein (alpha subunit)" /protein_id="NP_390730.1" /db_xref="EnsemblGenomes-Gn:BSU28520" /db_xref="EnsemblGenomes-Tr:CAB14812" /db_xref="GOA:P94551" /db_xref="InterPro:IPR001308" /db_xref="InterPro:IPR014729" /db_xref="InterPro:IPR014730" /db_xref="InterPro:IPR014731" /db_xref="InterPro:IPR018206" /db_xref="InterPro:IPR029035" /db_xref="InterPro:IPR033947" /db_xref="SubtiList:BG11934" /db_xref="UniProtKB/Swiss-Prot:P94551" /translation="MGKKVIVLGEIRDGELRNVTFEAIAAGRTISGDGEVIGVLIGEN VQSIAQELIHYGADKVLTAEDPKLKTYTADGYSQVMRGVIEQENPDSVIFGHTAMGKD LSPKLAARLQTGLISDAIDVSVTGGNVVFTRPIYSGKAFERVISTDPMIFATIRPNNI QASEKDTSRSGSIESIDVSLTDLRTVIQEVVKKTADGVDLSEAKIIVAGGRGVKSKEG FQPLQELAEVLGAAVGASRGACDADYCDYALQIGQTGKVVTPDLYIACGISGAIQHLA GMSNSKVIVAINKDPEADIFKIADYGIVGDLFEVVPLLTEEFKQLNIHS*" gene complement(2780963..2781940) /gene="etfA" /locus_tag="BSU_28520" /old_locus_tag="BSU28520" downshifts complement(2780971) /Source="Nicolas_upshifts" /id="D1461" /incds=0 /nref=58 /ntot=179 /MaxReadThrough="2.43782" /MaxDrop="7.95053" /score="30.2462458" /energy="-13.5" /TU="NA" /idTUdmin="U2210" /TUdmin="-2" /isTUend="TRUE" CDS complement(2781976..2782749) /gene="etfB" /locus_tag="BSU_28530" /old_locus_tag="BSU28530" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:10026281, 17189250, 21398533" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10026281, 17189250, 21398533; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="electron transfer flavoprotein (beta subunit)" /protein_id="NP_390731.1" /db_xref="EnsemblGenomes-Gn:BSU28530" /db_xref="EnsemblGenomes-Tr:CAB14813" /db_xref="GOA:P94550" /db_xref="InterPro:IPR000049" /db_xref="InterPro:IPR012255" /db_xref="InterPro:IPR014729" /db_xref="InterPro:IPR014730" /db_xref="InterPro:IPR033948" /db_xref="SubtiList:BG11935" /db_xref="UniProtKB/Swiss-Prot:P94550" /translation="MNLFVLMKRTFDTEEKIVIETGKIQDDGAEWIINPYDEYAIEEA IQLKEKHGGTITAVTVGGEEAEKELRTALAMGCDQAVLINIEDDLDEPDQYSISQVLY HYMKDQEFDLILGGNVAIDGGSGQVAPRLAELLDIPCITTITKLEINGTDAEAERDVE GDVEKIKTTLPLLVTAQQGLNEPRYPSLPGIMKAKKKPLEELELDDLDLDEEDAEPKL KTIERFLPPKKEAGKLLQGEPAEQAKELVSLLRSEAKVI*" gene complement(2781976..2782749) /gene="etfB" /locus_tag="BSU_28530" /old_locus_tag="BSU28530" CDS complement(2782764..2783540) /gene="fadB" /locus_tag="BSU_28540" /old_locus_tag="BSU28540" /EC_number="4.2.1.17" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:17189250, 21398533" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 17189250, 21398533; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="enoyl-CoA hydratase" /protein_id="NP_390732.1" /db_xref="EnsemblGenomes-Gn:BSU28540" /db_xref="EnsemblGenomes-Tr:CAB14814" /db_xref="GOA:P94549" /db_xref="InterPro:IPR001753" /db_xref="InterPro:IPR014748" /db_xref="InterPro:IPR018376" /db_xref="InterPro:IPR029045" /db_xref="SubtiList:BG12331" /db_xref="UniProtKB/Swiss-Prot:P94549" /translation="MNAISLAVDQFVAVLTIHNPPANALSSRILEELSSCLDQCETDA GVRSIIIHGEGRFFSAGADIKEFTSLKGNEDSSLLAERGQQLMERIESFPKPIIAAIH GAALGGGLELAMACHIRIAAEDAKLGLPELNLGIIPGFAGTQRLPRYVGTAKALELIG SGEPISGKEALDLGLVSIGAKDEAEVIEKAKALAAKFAEKSPQTLASLLELLYSNKVY SYEGSLKLEAKRFGEAFESEDAKEGIQAFLEKRKPQFKGE*" gene complement(2782764..2783540) /gene="fadB" /locus_tag="BSU_28540" /old_locus_tag="BSU28540" downshifts 2782829 /Source="Nicolas_upshifts" /id="D1462" /incds=1 /nref=1 /ntot=21 /MaxReadThrough="0.92259" /MaxDrop="4.42725" /score="-8.29305955" /energy="-5.1" /TU="NA" /idTUdmin="U2203" /TUdmin=7767 /isTUend="FALSE" CDS complement(2783555..2784139) /gene="fadR" /locus_tag="BSU_28550" /old_locus_tag="BSU28550" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:17189250, 18941141, 21398533, 24356978" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 17189250, 18941141, 21398533, 24356978; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator of fatty acids degradation [FadR-long-chain (C14-C20) acyl-CoAs]" /protein_id="NP_390733.1" /db_xref="EnsemblGenomes-Gn:BSU28550" /db_xref="EnsemblGenomes-Tr:CAB14815" /db_xref="GOA:P94548" /db_xref="InterPro:IPR001647" /db_xref="InterPro:IPR009057" /db_xref="InterPro:IPR013570" /db_xref="InterPro:IPR036271" /db_xref="PDB:1VI0" /db_xref="PDB:3WHB" /db_xref="PDB:3WHC" /db_xref="SubtiList:BG12330" /db_xref="UniProtKB/Swiss-Prot:P94548" /translation="MKQKRPKYMQIIDAAVEVIAENGYHQSQVSKIAKQAGVADGTIY LYFKNKEDILISLFKEKMGQFIERMEEDIKEKATAKEKLALVISKHFSLLAGDHNLAI VTQLELRQSNLELRQKINEILKGYLNILDGILTEGIQSGEIKEGLDVRLARQMIFGTI DETVTTWVMNDQKYDLVALSNSVLELLVSGIHNK*" gene complement(2783555..2784139) /gene="fadR" /locus_tag="BSU_28550" /old_locus_tag="BSU28550" promotor_-10 complement(2784181..2784200) /Source="Nicolas_upshift_promotors" /id="U2210" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.596403596403596" /psig=1 /xcortree=372 /SigmaFactorBS="aaagagaacgcctatgaataaACTTGACAaacctgaaaatcC TTCTTATCATGAAATTATGaatgaatagtcattcatttctataggaaggaacgatgaa c" /listShort="fadR, fadB, etfB, etfA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2784181) /Source="Nicolas_upshifts" /id="U2210" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.596403596403596" /psig=1 /xcortree=372 /SigmaFactorBS="aaagagaacgcctatgaataaACTTGACAaacctgaaaatcC TTCTTATCATGAAATTATGaatgaatagtcattcatttctataggaaggaacgatgaa c" /listShort="fadR, fadB, etfB, etfA" /GFF_Attribute="listLong" promotor_-35 complement(2784213..2784220) /Source="Nicolas_upshift_promotors" /id="U2210" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.596403596403596" /psig=1 /xcortree=372 /SigmaFactorBS="aaagagaacgcctatgaataaACTTGACAaacctgaaaatcC TTCTTATCATGAAATTATGaatgaatagtcattcatttctataggaaggaacgatgaa c" /listShort="fadR, fadB, etfB, etfA" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2784244..2785926) /gene="lcfA" /locus_tag="BSU_28560" /old_locus_tag="BSU28560" /EC_number="6.2.1.3" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:17085570, 17189250, 21398533, 21673922" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 17085570, 17189250, 21398533, 21673922; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="long chain acyl-CoA ligase (degradative)" /protein_id="NP_390734.1" /db_xref="EnsemblGenomes-Gn:BSU28560" /db_xref="EnsemblGenomes-Tr:CAB14816" /db_xref="GOA:P94547" /db_xref="InterPro:IPR000873" /db_xref="InterPro:IPR020845" /db_xref="InterPro:IPR025110" /db_xref="SubtiList:BG11946" /db_xref="UniProtKB/Swiss-Prot:P94547" /translation="MQSQKPWLAEYPNDIPHELPLPNKTLQSILTDSAARFPDKTAIS FYGKKLTFHDILTDALKLAAFLQCNGLQKGDRVAVMLPNCPQTVISYYGVLFAGGIVV QTNPLYTEHELEYQLRDAQVSVIITLDLLFPKAIKMKTLSIVDQILITSVKDYLPFPK NILYPLTQKQKVHIDFDKTANIHTFASCMKQEKTELLTIPKIDPEHDIAVLQYTGGTT GAPKGVMLTHQNILANTEMCAAWMYDVKEGAEKVLGIVPFFHVYGLTAVMNYSIKLGF EMILLPKFDPLETLKIIDKHKPTLFPGAPTIYIGLLHHPELQHYDLSSIKSCLSGSAA LPVEVKQKFEKVTGGKLVEGYGLSEASPVTHANFIWGKNKPGSIGCPWPSTDAAIYSE ETGELAAPYEHGEIIVKGPQVMKGYWNKPEETAAVLRDGWLFTGDMGYMDEEGFFYIA DRKKDIIIAGGYNIYPREVEEALYEHEAIQEIVVAGVPDSYRGETVKAFVVLKKGAKA DTEELDAFARSRLAPYKVPKAYEFRKELPKTAVGKILRRRLLEEETENHHIK*" gene complement(2784244..2785926) /gene="lcfA" /locus_tag="BSU_28560" /old_locus_tag="BSU28560" misc_feature complement(2785955..2785974) /Source="Nicolas_upshift_promotors" /id="U2211" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.411588411588412" /psig="0.985014985014985" /xcortree=352 /SigmaFactorBS="tatgagaaaaagaaagatttacctttctttttcttttttttg ccgtccaTCTGCTATAATGATAAGGTGgatctctaaaatcgaaaggggaggttttatg c" /listShort="lcfA, fadR, fadB, etfB, etfA" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(2785963) /Source="Nicolas_upshifts" /id="U2211" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.411588411588412" /psig="0.985014985014985" /xcortree=352 /SigmaFactorBS="tatgagaaaaagaaagatttacctttctttttcttttttttg ccgtccaTCTGCTATAATGATAAGGTGgatctctaaaatcgaaaggggaggttttatg c" /listShort="lcfA, fadR, fadB, etfB, etfA" /GFF_Attribute="listLong" downshifts complement(2786051) /Source="Nicolas_upshifts" /id="D1463" /incds=0 /nref=8 /ntot=101 /MaxReadThrough="2.17789" /MaxDrop="3.3655" /score="10.932726" /energy="-9.8" /TU="U2212" /idTUdmin="U2212" /TUdmin="-22" /isTUend="TRUE" CDS complement(2786115..2786519) /gene="yshE" /locus_tag="BSU_28570" /old_locus_tag="BSU28570" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative integral inner membrane protein" /protein_id="NP_390735.1" /db_xref="EnsemblGenomes-Gn:BSU28570" /db_xref="EnsemblGenomes-Tr:CAB14817" /db_xref="GOA:P94546" /db_xref="InterPro:IPR007140" /db_xref="SubtiList:BG12329" /db_xref="UniProtKB/Swiss-Prot:P94546" /translation="MSDFWENELVEIAAYYSVAVLCLVLFLTVFELVTAYKNWEEIQK GNLAVAMATGGKILGIANVFQHSISQHNSLLQMIGWGVYGFVMLLISYFIFEFLTPRF KIDQEIENDNRAVGFISFVISVGLSFVVAAGI*" gene complement(2786115..2786519) /gene="yshE" /locus_tag="BSU_28570" /old_locus_tag="BSU28570" downshifts complement(2786117) /Source="Nicolas_upshifts" /id="D1464" /incds=0 /nref=1 /ntot=75 /MaxReadThrough="3.74343" /MaxDrop="2.92029" /score="10.932726" /energy="-9.8" /TU="U2212" /idTUdmin="U2212" /TUdmin="-88" /isTUend="FALSE" CDS complement(2786534..2788891) /gene="mutSB" /locus_tag="BSU_28580" /old_locus_tag="BSU28580" /function="16.8: Protect" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:11254128, 12719520, 22333191, 27799325" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11254128, 12719520, 22333191, 27799325; Product type f: factor" /codon_start=1 /transl_table=11 /product="homologous recombination factor" /protein_id="NP_390736.1" /db_xref="EnsemblGenomes-Gn:BSU28580" /db_xref="EnsemblGenomes-Tr:CAB14818" /db_xref="GOA:P94545" /db_xref="InterPro:IPR000432" /db_xref="InterPro:IPR002625" /db_xref="InterPro:IPR005747" /db_xref="InterPro:IPR007696" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR036063" /db_xref="InterPro:IPR036187" /db_xref="SubtiList:BG12328" /db_xref="UniProtKB/Swiss-Prot:P94545" /translation="MQQKVLSALEFHKVKEQVIGHAASSLGKEMLLELKPSASIDEIK KQLDEVDEASDIIRLRGQAPFGGLVDIRGALRRAEIGSVLSPSEFTEISGLLYAVKQM KHFITQMAEDGVDIPLIHQHAEQLITLSDLERDINSCIDDHGEVLDHASETLRGIRTQ LRTLESRVRDRLESMLRSSSASKMLSDTIVTIRNDRFVIPVKQEYRSSYGGIVHDTSS SGATLFIEPQAIVDMNNSLQQAKVKEKQEIERILRVLTEKTAEYTEELFLDLQVLQTL DFIFAKARYAKAVKATKPIMNDTGFIRLKKARHPLLPPDQVVANDIELGRDFSTIVIT GPNTGGKTVTLKTLGLLTLMAQSGLHIPADEGSEAAVFEHVFADIGDEQSIEQSLSTF SSHMVNIVGILEQVNENSLVLFDELGAGTDPQEGAALAMSILDDVHRTNARVLATTHY PELKAYGYNREGVMNASVEFDIETLSPTYKLLIGVPGRSNAFEISKRLGLPDHIIGQA KSEMTAEHNEVDTMIASLEQSKKRAEEELSETESIRKEAEKLHKELQQQIIELNSKKD KMLEEAEQQAAEKVKAAMKEAEDIIHELRTIKEEHKSFKDHELINAKKRLEGAMPAFE KSKKPEKPKTQKRDFKPGDEVKVLTFGQKGTLLEKTGGNEWNVQIGILKMKVKEKDLE FIKSAPEPKKEKMITAVKGKDYHVSLELDLRGERYENALSRVEKYLDDAVLAGYPRVS IIHGKGTGALRKGVQDLLKNHRSVKSSRFGEAGEGGSGVTVVELK*" gene complement(2786534..2788891) /gene="mutSB" /locus_tag="BSU_28580" /old_locus_tag="BSU28580" CDS complement(2788912..2790624) /gene="polX" /locus_tag="BSU_28590" /old_locus_tag="BSU28590" /EC_number="2.7.7.7" /EC_number="3.1.11.-" /function="16.6: Maintain" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:18776221, 18938175, 28254425" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 18776221, 18938175, 28254425; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="DNA polymerase/3'-5' exonuclease X" /protein_id="NP_390737.1" /db_xref="EnsemblGenomes-Gn:BSU28590" /db_xref="EnsemblGenomes-Tr:CAB14819" /db_xref="GOA:P94544" /db_xref="InterPro:IPR002054" /db_xref="InterPro:IPR003141" /db_xref="InterPro:IPR003583" /db_xref="InterPro:IPR004013" /db_xref="InterPro:IPR010996" /db_xref="InterPro:IPR016195" /db_xref="InterPro:IPR022311" /db_xref="InterPro:IPR027421" /db_xref="InterPro:IPR029398" /db_xref="InterPro:IPR037160" /db_xref="SubtiList:BG12327" /db_xref="UniProtKB/Swiss-Prot:P94544" /translation="MHKKDIIRLLETIAVYMELKGDNPFKVSAFRKAAAALEQDDRSL SEMDDMMSLSGIGKGTYSVIKEYIDEGKSSTLESLQKEVPEGLVPLLKLPGLGGKKIA KLYKELGVHDAESLKEACEQQKVQGLAGFGKKSEEKILQALGEAGKQPERFPIGYALR IAREIEEHLSQFTHIIKFSRAGSLRRARETVKDLDYIIATDHPAEVREQLLELPNIKS VIASGDTKVSVILSFEYETSVDFRLVTEEQFPTTLHHFTGSKDHNIKMRQIAKERGER ISEYGVETVETGEIKTFPSEREFYAHFGLPLIPPEIRESGQEVETYSDSIELIELGQI KGDLHMHSTWSDGAFSIREMAEACIKKGYQYMAITDHSQYLKVANGLTAERLKQQAKE IDALNAEFENFRILKGVEMDILPDGTLDYDDDVLAEMDIVIASIHSSFNQPEHVIMKR LETALTNKHVDIIAHPTGRLIGRRAGYEIDIDQLIELARKTNTALELNANPARLDLRT EHLMKANEQGVTLVINTDAHNIEMLDDMKTGVTAARKGWTETKNVLNARSLKDVEAFL KRND*" gene complement(2788912..2790624) /gene="polX" /locus_tag="BSU_28590" /old_locus_tag="BSU28590" S_feature complement(2790625..2790697) /Source="Nicolas_S_feature" /locus_tag="new_2925027_2925099_c" /HighExp="Cold, LPhT, LBGstat, H2O2, dia15, G180, G135, Sw, G150, Paraq" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1080" CDS complement(2790698..2791231) /gene="yshB" /locus_tag="BSU_28600" /old_locus_tag="BSU28600" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative integral membrane protein" /protein_id="NP_390738.1" /db_xref="EnsemblGenomes-Gn:BSU28600" /db_xref="EnsemblGenomes-Tr:CAB14820" /db_xref="GOA:P94543" /db_xref="InterPro:IPR003825" /db_xref="SubtiList:BG12326" /db_xref="UniProtKB/Swiss-Prot:P94543" /translation="MLDIIILILLLMGTLLGLKRGFILQFIRLTSFILSIAFAALFYK NVAPHLHWIPAPDFSAGQPALSFFTGNLEAAYYNAIAFIVLFIIAKILLRIIGSFLSI VAGIPVIKQINQMLGAVLGFLEVYLFTFVLLYVASVLPVDALQQMMGQSSLANVIINH TPYLSGLLQELWTQYGA*" gene complement(2790698..2791231) /gene="yshB" /locus_tag="BSU_28600" /old_locus_tag="BSU28600" CDS complement(2791238..2791495) /gene="zapA" /locus_tag="BSU_28610" /old_locus_tag="BSU28610" /experiment="publication(s) with functional evidences, PMID:15317782, 16796675, 18588879, 20711458, 24097947, 26258635" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15317782, 16796675, 18588879, 20711458, 24097947, 26258635; Product type r : regulator" /codon_start=1 /transl_table=11 /product="regulator of cell division" /protein_id="NP_390739.1" /db_xref="EnsemblGenomes-Gn:BSU28610" /db_xref="EnsemblGenomes-Tr:CAB14821" /db_xref="GOA:P94542" /db_xref="InterPro:IPR007838" /db_xref="InterPro:IPR023688" /db_xref="InterPro:IPR036192" /db_xref="SubtiList:BG12325" /db_xref="UniProtKB/Swiss-Prot:P94542" /translation="MSDGKKTKTTVDIYGQHFTIVGEESRAHMRYVAGIVDDKMREIN EKNPYLDINKLAVLTAVNVVHDYVKLQEKCEKLERQLKEKD*" gene complement(2791238..2791495) /gene="zapA" /locus_tag="BSU_28610" /old_locus_tag="BSU28610" promotor_-10 complement(2791522..2791541) /Source="Nicolas_upshift_promotors" /id="U2212" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.992007992007992" /psig=1 /xcortree=2168 /SigmaFactorBS="tgtatataccagtgtatcataacagcgggaggctcgtcTTTC CATTcatttaataaaCGTGTTATGATAAGAACTAGgattctcgcggaatggaggagaa a" /listShort="yshA, yshB, S1080, polX, mutSB, yshE" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2791538) /Source="Nicolas_upshifts" /id="U2212" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.992007992007992" /psig=1 /xcortree=2168 /SigmaFactorBS="tgtatataccagtgtatcataacagcgggaggctcgtcTTTC CATTcatttaataaaCGTGTTATGATAAGAACTAGgattctcgcggaatggaggagaa a" /listShort="yshA, yshB, S1080, polX, mutSB, yshE" /GFF_Attribute="listLong" promotor_-35 complement(2791553..2791560) /Source="Nicolas_upshift_promotors" /id="U2212" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.992007992007992" /psig=1 /xcortree=2168 /SigmaFactorBS="tgtatataccagtgtatcataacagcgggaggctcgtcTTTC CATTcatttaataaaCGTGTTATGATAAGAACTAGgattctcgcggaatggaggagaa a" /listShort="yshA, yshB, S1080, polX, mutSB, yshE" /GFF_Attribute="listLong" /label="promotor_-35" misc_feature 2791578..2791597 /Source="Nicolas_upshift_promotors" /id="U2213" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.987012987012987" /psig="0.999000999001" /xcortree=2131 /SigmaFactorBS="gttcttatcataacacgtttattaaatgaatggaaagacgag cctcccgctgtTATGATACACTGGTATATACagcgaaaagtgtaaaaaaaggagatta t" /listShort="rnhC" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 2791585 /Source="Nicolas_upshifts" /id="U2213" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.987012987012987" /psig="0.999000999001" /xcortree=2131 /SigmaFactorBS="gttcttatcataacacgtttattaaatgaatggaaagacgag cctcccgctgtTATGATACACTGGTATATACagcgaaaagtgtaaaaaaaggagatta t" /listShort="rnhC" /GFF_Attribute="listLong" CDS 2791629..2792570 /gene="rnhC" /locus_tag="BSU_28620" /old_locus_tag="BSU28620" /EC_number="3.1.26.4" /function="16.6: Maintain" /function="16.2: Construct biomass (Anabolism)" /function="16.9: Replicate" /experiment="publication(s) with functional evidences, PMID:9888800, 10094689, 12794188, 23882084" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9888800, 10094689, 12794188, 23882084; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="ribonuclease HIII" /protein_id="NP_390740.1" /db_xref="EnsemblGenomes-Gn:BSU28620" /db_xref="EnsemblGenomes-Tr:CAB14822" /db_xref="GOA:P94541" /db_xref="InterPro:IPR001352" /db_xref="InterPro:IPR004641" /db_xref="InterPro:IPR012337" /db_xref="InterPro:IPR024567" /db_xref="InterPro:IPR024568" /db_xref="InterPro:IPR036397" /db_xref="SubtiList:BG12324" /db_xref="UniProtKB/Swiss-Prot:P94541" /translation="MSHSVIKVSLSAIDQMKMTYSGSLTASVPQGAVFQAKPPGCTIT AYQSGKVLFQGKNAAAESARWGTAEPQEKKKTAKKPADPRYAPPADIAGMSVIGSDEV GTGDYFGPMTVVCAYVDKTMLPLMKELGVKDSKDLKDPQIIEIARNLIKTIPYSLLVL KNEKYNSMQEKGMSQGKMKALLHNQAITHLLRKLDGVKPEAILIDQFAEPGVYFNHLK GRDIVKERTYFSTKAEGIHLAVAAASIIARYSFLMEMDKLSRAAGMTLPKGAGPHVDE AAAKLILKKGASALRTFTKLHFANTQKAQRLADKKRS*" gene 2791629..2792570 /gene="rnhC" /locus_tag="BSU_28620" /old_locus_tag="BSU28620" promotor_-10 complement(2792302..2792321) /Source="Nicolas_upshift_promotors" /id="U2214" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.586413586413586" /psig="0.998001998001998" /xcortree=2466 /SigmaFactorBS="gaatatcttgcaatgattgaagcagcggcgacagcCAGGTGA AtaccttcagctttTGTGCTAAAATAGGTCCGCTccttcacaatgtctctgcccttta a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2792317) /Source="Nicolas_upshifts" /id="U2214" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.586413586413586" /psig="0.998001998001998" /xcortree=2466 /SigmaFactorBS="gaatatcttgcaatgattgaagcagcggcgacagcCAGGTGA AtaccttcagctttTGTGCTAAAATAGGTCCGCTccttcacaatgtctctgcccttta a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(2792335..2792342) /Source="Nicolas_upshift_promotors" /id="U2214" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.586413586413586" /psig="0.998001998001998" /xcortree=2466 /SigmaFactorBS="gaatatcttgcaatgattgaagcagcggcgacagcCAGGTGA AtaccttcagctttTGTGCTAAAATAGGTCCGCTccttcacaatgtctctgcccttta a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 2792553 /Source="Nicolas_upshifts" /id="D1465" /incds=0 /nref=150 /ntot=232 /MaxReadThrough="1.71535" /MaxDrop="5.25365" /score="25.6336933" /energy="-13.7" /TU="NA" /idTUdmin="U2213" /TUdmin=0 /isTUend="TRUE" downshifts complement(2792585) /Source="Nicolas_upshifts" /id="D1466" /incds=0 /nref=1 /ntot=5 /MaxReadThrough="2.4685" /MaxDrop="5.29665" /score="-4.45611985" /energy="-14.9" /TU="NA" /idTUdmin="U2216" /TUdmin=44 /isTUend="FALSE" CDS complement(2792606..2795020) /gene="pheT" /locus_tag="BSU_28630" /old_locus_tag="BSU28630" /EC_number="6.1.1.20" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:811647, 2127701, 2492510, 12682299" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 811647, 2127701, 2492510, 12682299; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="phenylalanyl-tRNA synthetase (beta subunit)" /protein_id="NP_390741.1" /db_xref="EnsemblGenomes-Gn:BSU28630" /db_xref="EnsemblGenomes-Tr:CAB14823" /db_xref="GOA:P17922" /db_xref="InterPro:IPR002547" /db_xref="InterPro:IPR004532" /db_xref="InterPro:IPR005121" /db_xref="InterPro:IPR005146" /db_xref="InterPro:IPR005147" /db_xref="InterPro:IPR009061" /db_xref="InterPro:IPR012340" /db_xref="InterPro:IPR020825" /db_xref="InterPro:IPR033714" /db_xref="InterPro:IPR036690" /db_xref="SubtiList:BG10875" /db_xref="UniProtKB/Swiss-Prot:P17922" /translation="MFVSYKWLEDYVDLKGMDPAVLAEKITRAGIEVEGIEYKGEGIK GVVIGHVLEREQHPNADKLNKCLVDIGAEAPVQIICGAPNVDKGQKVAVATVGAVLPG NFKIKKAKLRGEESNGMICSLQELGIESKLVAKEYAEGIFVFPNDAETGSDALAALQL DDAILELGLTPNRADAMNMLGVAYEVAAILDTEVKLPQTDYPAASEQASDYISVKIED QEANPLYTAKIIKNVTIAPSPLWMQTKLMNAGIRPHNNVVDITNFVLLEYGQPLHAFD YDRFGSKEVVVRKAAENEMIVTLDDQERKLSADHLVITNGTKAQAVAGVMGGAESEVQ EDTKTILLEAAYFNGQKVRKASKDLGLRSESSVRFEKGIDPARVRLAAERAAQLIHLY AGGEVLAGTVEEDHLTIEANNIHVSADKVSSVLGLTISKEELISIYKRLGFTVGEADD LLVVTVPSRRGDITIEEDLIEEAARLYGYDNIPSTLPETAGTTGGLTPYQAKRRKVRR FLEGAGLSQAITYSLTNEKKATAFAIEKSLNTVLALPMSEERSILRHSLVPNLLDSVS YNLARQTDSVALYEVGSVFLTKEEDTKPVETERVAGAVTGLWRKQLWQGEKKPVDFFV VKGIVEGLLDKLNVLDSIEFVQSERKQLHPGRTANILLNGSLIGFIGQVHPSLEKELD IKETYVFELDLHALLAAETAPLVYTAIPKYPSVTRDIALVTDKTVTSGQLESVIKEAG GKLLKEVTVFDVYEGEHMEEGKKSVAFSLQYVNPEQTLTEEEVTKAHSKVLKALEDTY QAVLRG*" gene complement(2792606..2795020) /gene="pheT" /locus_tag="BSU_28630" /old_locus_tag="BSU28630" downshifts complement(2792629) /Source="Nicolas_upshifts" /id="D1467" /incds=0 /nref=214 /ntot=255 /MaxReadThrough="3.98669" /MaxDrop="7.11892" /score="32.4736491" /energy="-14.7" /TU="NA" /idTUdmin="U2216" /TUdmin=0 /isTUend="TRUE" CDS complement(2795036..2796070) /gene="pheS" /locus_tag="BSU_28640" /old_locus_tag="BSU28640" /EC_number="6.1.1.20" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:811647, 2127701, 2492510, 12682299" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 811647, 2127701, 2492510, 12682299; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="phenylalanyl-tRNA synthetase (alpha subunit)" /protein_id="NP_390742.1" /db_xref="EnsemblGenomes-Gn:BSU28640" /db_xref="EnsemblGenomes-Tr:CAB14824" /db_xref="GOA:P17921" /db_xref="InterPro:IPR002319" /db_xref="InterPro:IPR004188" /db_xref="InterPro:IPR004529" /db_xref="InterPro:IPR006195" /db_xref="InterPro:IPR010978" /db_xref="InterPro:IPR022911" /db_xref="SubtiList:BG10874" /db_xref="UniProtKB/Swiss-Prot:P17921" /translation="MEEKLKQLEQEALEQVEAASSLKVVNDIRVQYLGKKGPITEVLR GMGKLSAEERPKMGALANEVRERIANAIADKNEKLEEEEMKQKLAGQTIDVTLPGNPV AVGGRHPLTVVIEEIEDLFIGMGYTVEEGPEVETDYYNFESLNLPKEHPARDMQDSFY ITEETLMRTQTSPVQTRTMEKHEGKGPVKIICPGKVYRRDNDDATHSHQFMQIEGLVV DKNISMSDLKGTLELVAKKMFGQDREIRLRPSFFPFTEPSVEVDVTCFKCGGNGCSVC KGTGWIEILGAGMVHPNVLKMAGFDPKEYQGFAFGMGVERIAMLKYGIDDIRHFYTND VRFISQFKQA*" gene complement(2795036..2796070) /gene="pheS" /locus_tag="BSU_28640" /old_locus_tag="BSU28640" S_feature complement(2796071..2796391) /Source="Nicolas_S_feature" /locus_tag="new_2930473_2930793_c" /HighExp="HPh, Cold, GM 15, GM 10, Sw, C30, G150, MG-0.2, G135, C90" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="SigA" /TUlongPSig=1 /label="S1081" CDS 2796152..2796358 /locus_tag="BSU_28645" /old_locus_tag="BSU28645" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_009513995.1" /translation="MWPRYHPYFRQTDAVVSFIDITESDSGSPLRAVYAVPATTQEVK PISGCVKNALSQRHFLPGKQLIRN*" gene 2796152..2796358 /locus_tag="BSU_28645" /old_locus_tag="BSU28645" S_feature 2796381..2796645 /Source="Nicolas_S_feature" /locus_tag="new_2930783_2931047" /HighExp="S8, S7, S6, BT, C30, B36, S5, Pyr, C90, Glucon" /AntisenseName="ysgA" /AntisenseCor="-0.23049778674462801" /AntisenseRegPval="-3.9" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.519" /TUlongSig="NA" /TUlongPSig="NA" /label="S1082" upshifts 2796381 /Source="Nicolas_upshifts" /id="U2215" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.411588411588412" /psig="0.519480519480519" /xcortree=1240 /SigmaFactorBS="ggcattttctccctggaaagcagttgatcagaaattgaggtc ctctgtcacggtttttgaaatattaTGTTCTATTATAGAGaaatccaacgcttggcgc a" /listShort="S1082" /GFF_Attribute="listLong" promotor_-10 complement(2796386..2796405) /Source="Nicolas_upshift_promotors" /id="U2216" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.977022977022977" /psig=1 /xcortree=2133 /SigmaFactorBS="atcctcgtgtatcacttgcgaggatagtGTTGcgccaagcgt tggaTTTCTCTATAATAGAACATAatatttcaaaaaccgtgacagaggacctcaattt c" /listShort="S1081, pheS, pheT" /GFF_Attribute="listLong" /label="promotor_-10" misc_feature 2796388..2796402 /Source="Nicolas_upshift_promotors" /id="U2215" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.411588411588412" /psig="0.519480519480519" /xcortree=1240 /SigmaFactorBS="ggcattttctccctggaaagcagttgatcagaaattgaggtc ctctgtcacggtttttgaaatattaTGTTCTATTATAGAGaaatccaacgcttggcgc a" /listShort="S1082" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(2796391) /Source="Nicolas_upshifts" /id="U2216" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.977022977022977" /psig=1 /xcortree=2133 /SigmaFactorBS="atcctcgtgtatcacttgcgaggatagtGTTGcgccaagcgt tggaTTTCTCTATAATAGAACATAatatttcaaaaaccgtgacagaggacctcaattt c" /listShort="S1081, pheS, pheT" /GFF_Attribute="listLong" promotor_-35 complement(2796420..2796423) /Source="Nicolas_upshift_promotors" /id="U2216" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.977022977022977" /psig=1 /xcortree=2133 /SigmaFactorBS="atcctcgtgtatcacttgcgaggatagtGTTGcgccaagcgt tggaTTTCTCTATAATAGAACATAatatttcaaaaaccgtgacagaggacctcaattt c" /listShort="S1081, pheS, pheT" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2796425..2797171) /gene="rlmBB" /locus_tag="BSU_28650" /old_locus_tag="BSU28650" /EC_number="2.1.1.-" /function="16.6: Maintain" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2b: Function from indirect experimental evidences (e.g. phenotypes); PubMedId: 17114254, 24809820, 27435445; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="ribosomal RNA methylase" /protein_id="NP_390743.1" /db_xref="EnsemblGenomes-Gn:BSU28650" /db_xref="EnsemblGenomes-Tr:CAB14825" /db_xref="GOA:P94538" /db_xref="InterPro:IPR001537" /db_xref="InterPro:IPR013123" /db_xref="InterPro:IPR029026" /db_xref="InterPro:IPR029028" /db_xref="InterPro:IPR029064" /db_xref="SubtiList:BG12323" /db_xref="UniProtKB/Swiss-Prot:P94538" /translation="MKQIESAKNQKVKDWKKLHTKKERTKTNTFLIEGEHLVEEALKS PGIVKEILVKDETRIPSDLETGIQCYMLSEDAFSAVTETETPQQIAAVCHMPEEKLAT ARKVLLIDAVQDPGNLGTMIRTADAAGLDAVVLGDGTADAFNGKTLRSAQGSHFHIPV VRRNLPSYVDELKAEGVKVYGTALQNGAPYQEIPQSESFALIVGNEGAGVDAALLEKT DLNLYVPLYGQAESLNVAVAAAILVYHLRG*" gene complement(2796425..2797171) /gene="rlmBB" /locus_tag="BSU_28650" /old_locus_tag="BSU28650" promotor_-10 complement(2797198..2797217) /Source="Nicolas_upshift_promotors" /id="U2217" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.436563436563437" /psig=1 /xcortree=2411 /SigmaFactorBS="taaaatgtaatacgtatattctaaccctgcacctGGTTTATt atgtgctgttctTGCGATATAATAACATCATGttaaaaaaaggagcgccacatagaca g" /listShort="ysgA" /listLong="S1081, pheS, pheT" /label="promotor_-10" promotor_-35 2797204..2797210 /Source="Nicolas_upshift_promotors" /id="U2218" /multdbtbs="SigG,SigG" /comp="M8" /sig="SigGF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=944 /SigmaFactorBS="tgtggcgctcctttttttaacatgatGTTATTAtatcgcaag aacaGCACATAATAAAccaggtgcagggttagaatatacgtattacattttagaaaaa g" /listShort="sspI, ysfB" /GFF_Attribute="listLong" /label="promotor_-35" upshifts complement(2797211) /Source="Nicolas_upshifts" /id="U2217" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.436563436563437" /psig=1 /xcortree=2411 /SigmaFactorBS="taaaatgtaatacgtatattctaaccctgcacctGGTTTATt atgtgctgttctTGCGATATAATAACATCATGttaaaaaaaggagcgccacatagaca g" /listShort="ysgA" /listLong="S1081, pheS, pheT" promotor_-10 2797224..2797235 /Source="Nicolas_upshift_promotors" /id="U2218" /multdbtbs="SigG,SigG" /comp="M8" /sig="SigGF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=944 /SigmaFactorBS="tgtggcgctcctttttttaacatgatGTTATTAtatcgcaag aacaGCACATAATAAAccaggtgcagggttagaatatacgtattacattttagaaaaa g" /listShort="sspI, ysfB" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 complement(2797231..2797237) /Source="Nicolas_upshift_promotors" /id="U2217" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.436563436563437" /psig=1 /xcortree=2411 /SigmaFactorBS="taaaatgtaatacgtatattctaaccctgcacctGGTTTATt atgtgctgttctTGCGATATAATAACATCATGttaaaaaaaggagcgccacatagaca g" /listShort="ysgA" /listLong="S1081, pheS, pheT" /label="promotor_-35" upshifts 2797238 /Source="Nicolas_upshifts" /id="U2218" /multdbtbs="SigG,SigG" /comp="M8" /sig="SigGF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=944 /SigmaFactorBS="tgtggcgctcctttttttaacatgatGTTATTAtatcgcaag aacaGCACATAATAAAccaggtgcagggttagaatatacgtattacattttagaaaaa g" /listShort="sspI, ysfB" /GFF_Attribute="listLong" CDS 2797290..2797505 /gene="sspI" /locus_tag="BSU_28660" /old_locus_tag="BSU28660" /function="16.8: Protect" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:8171126, 10806362, 22720735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8171126, 10806362, 22720735; Product type f: factor" /codon_start=1 /transl_table=11 /product="small acid-soluble spore protein" /protein_id="NP_390744.1" /db_xref="EnsemblGenomes-Gn:BSU28660" /db_xref="EnsemblGenomes-Tr:CAB14826" /db_xref="GOA:P94537" /db_xref="InterPro:IPR017525" /db_xref="SubtiList:BG12318" /db_xref="UniProtKB/Swiss-Prot:P94537" /translation="MDLNLRHAVIANVTGNNQEQLEHTIVDAIQSGEEKMLPGLGVLF EVIWQHASESEKNEMLKTLEGGLKPAE*" gene 2797290..2797505 /gene="sspI" /locus_tag="BSU_28660" /old_locus_tag="BSU28660" S_feature complement(2797487..2798899) /Source="Nicolas_S_feature" /locus_tag="new_2931889_2933301_c" /HighExp="S6, S8, S7, BT, S5, C30, B36, S4, B60, C90" /AntisenseName="ysfB" /AntisenseCor="0.46970634471519201" /AntisenseRegPval="-15.4" /CDS_PredictionProba="NA" /TUshortSig="SigK" /TUshortPSig="0.998" /TUlongSig="NA" /TUlongPSig="NA" /label="S1083" promotor_-35 2797516..2797523 /Source="Nicolas_upshift_promotors" /id="U2219" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.702297702297702" /psig="0.998001998001998" /xcortree=3149 /SigmaFactorBS="attaaaacccgccgaataagacatgaaacCGGGTGACagcgc ccggttttttTCTTATATAATAAAAACATGatgagggggaacgccatgtttttacagc c" /listShort="ysfB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2797539..2797558 /Source="Nicolas_upshift_promotors" /id="U2219" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.702297702297702" /psig="0.998001998001998" /xcortree=3149 /SigmaFactorBS="attaaaacccgccgaataagacatgaaacCGGGTGACagcgc ccggttttttTCTTATATAATAAAAACATGatgagggggaacgccatgtttttacagc c" /listShort="ysfB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2797547 /Source="Nicolas_upshifts" /id="U2219" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.702297702297702" /psig="0.998001998001998" /xcortree=3149 /SigmaFactorBS="attaaaacccgccgaataagacatgaaacCGGGTGACagcgc ccggttttttTCTTATATAATAAAAACATGatgagggggaacgccatgtttttacagc c" /listShort="ysfB" /GFF_Attribute="listLong" CDS 2797574..2798680 /gene="ysfB" /locus_tag="BSU_28670" /old_locus_tag="BSU28670" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative transcriptional regulator (glycolate degradation operon)" /protein_id="NP_390745.2" /db_xref="EnsemblGenomes-Gn:BSU28670" /db_xref="EnsemblGenomes-Tr:CAB14827" /db_xref="InterPro:IPR008599" /db_xref="InterPro:IPR025736" /db_xref="SubtiList:BG12319" /db_xref="UniProtKB/Swiss-Prot:P94536" /translation="MFLQPLLAKKIIAEVKKMYEREVIIVNTDGLIMAGTNDERVGQF HEGALICAKERRSVIITKEDETRLKGVKAGINLPVFFDHDVIAVFGLTGEPAEIQPFG ELLRKMTELFIKESRHLEQSQWRERMLESFMIDWLQLKEWSPSFLEKAQLLGVDLSSR RQMILIQGYEWSPHDIEQMARSWKSSYPADLFIRWGNERILINHEVPQHEQRDRLLRK ILHICSFANTASSQYTAAGAGRAVASSSLTDSYEQAEKALAVSLKRKTPIFEEDLKLD MCLTEISPGTRNEFPQRVLGKALEHQELMNTIRTFFHHDLSLKQTAEDMHIHINTLRY RLAKAEQLTGLRFDRTEDVVTMYVALYFLDQDTK*" gene 2797574..2798680 /gene="ysfB" /locus_tag="BSU_28670" /old_locus_tag="BSU28670" promotor_-35 2798716..2798719 /Source="Nicolas_upshift_promotors" /id="U2220" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.732267732267732" /psig="0.999000999001" /xcortree=2772 /SigmaFactorBS="agagagagtttcagtttcattttttgtatgtttctccATGGa aggctttgctttttTTCTTTTACAATAGATTGAAagcgttttttgacagggggatggg t" /listShort="glcD, glcF" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2798735..2798754 /Source="Nicolas_upshift_promotors" /id="U2220" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.732267732267732" /psig="0.999000999001" /xcortree=2772 /SigmaFactorBS="agagagagtttcagtttcattttttgtatgtttctccATGGa aggctttgctttttTTCTTTTACAATAGATTGAAagcgttttttgacagggggatggg t" /listShort="glcD, glcF" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2798739 /Source="Nicolas_upshifts" /id="U2220" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.732267732267732" /psig="0.999000999001" /xcortree=2772 /SigmaFactorBS="agagagagtttcagtttcattttttgtatgtttctccATGGa aggctttgctttttTTCTTTTACAATAGATTGAAagcgttttttgacagggggatggg t" /listShort="glcD, glcF" /GFF_Attribute="listLong" CDS 2798783..2800195 /gene="glcD" /locus_tag="BSU_28680" /old_locus_tag="BSU28680" /EC_number="1.1.99.14" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 8606183, 25217009; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="glycolate oxidase subunit" /protein_id="NP_390746.1" /db_xref="EnsemblGenomes-Gn:BSU28680" /db_xref="EnsemblGenomes-Tr:CAB14828" /db_xref="GOA:P94535" /db_xref="InterPro:IPR004113" /db_xref="InterPro:IPR004490" /db_xref="InterPro:IPR006094" /db_xref="InterPro:IPR016164" /db_xref="InterPro:IPR016166" /db_xref="InterPro:IPR016167" /db_xref="InterPro:IPR016169" /db_xref="InterPro:IPR016171" /db_xref="InterPro:IPR036318" /db_xref="SubtiList:BG12320" /db_xref="UniProtKB/Swiss-Prot:P94535" /translation="MITKDVKEQLIQVSGPENFDDSNAGRLVYSYDATPQYQSMPDAV IAPRNTDEISRILTICSEHRVPIVPRGSGTNLCGGTCPTEGGLVLLFKHMNQILEIDE ENLTATVQPGVITLDMIRAVESKGLFYPPDPSSMKISTIGGNINENSGGLRGLKYGVT RDYVIGLEVVLANGDIIRTGGKLAKDVAGYDLTRLFVGSEGTLGIVTEAIVKLVPKPE TKKTLLALYENIDAAAQTVSDIIAAKIIPATLEFLDQPTLLVIEDYAKIGLPTSAKAV LLIEQDGPFETVERDMEKIEAICKKGDAVSVQTAQTEEEAFALTEARRSALSALARLK PTTILEDATVPRSEIANMVKAINDIAAKYDISICTFGHAGDGNLHPTCTTDIRNKDEM ERVEQAFAEIFEKAIELGGTITGEHGVGEMKAPYLEMKLKKEGIDAMKALKAAFDPRN ILNPGKMFAKDARKRVVAER*" gene 2798783..2800195 /gene="glcD" /locus_tag="BSU_28680" /old_locus_tag="BSU28680" promotor_-10 complement(2798885..2798904) /Source="Nicolas_upshift_promotors" /id="U2221" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=1308 /SigmaFactorBS="aattgttaaaatgcgtgatatttcatcagtattCCTCGGAGC AatcacggcatcaGGCATAGACTGATACTGAGGcgtcgcatcatatgaatagacgaga c" /listShort="S1083" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2798899) /Source="Nicolas_upshifts" /id="U2221" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=1308 /SigmaFactorBS="aattgttaaaatgcgtgatatttcatcagtattCCTCGGAGC AatcacggcatcaGGCATAGACTGATACTGAGGcgtcgcatcatatgaatagacgaga c" /listShort="S1083" /GFF_Attribute="listLong" promotor_-35 complement(2798917..2798926) /Source="Nicolas_upshift_promotors" /id="U2221" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=1308 /SigmaFactorBS="aattgttaaaatgcgtgatatttcatcagtattCCTCGGAGC AatcacggcatcaGGCATAGACTGATACTGAGGcgtcgcatcatatgaatagacgaga c" /listShort="S1083" /GFF_Attribute="listLong" /label="promotor_-35" CDS 2800192..2801526 /gene="glcF" /locus_tag="BSU_28690" /old_locus_tag="BSU28690" /EC_number="1.1.99.14" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 8606183, 25217009; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="glycolate oxidase (iron-sulfur subunit)" /protein_id="NP_390747.1" /db_xref="EnsemblGenomes-Gn:BSU28690" /db_xref="EnsemblGenomes-Tr:CAB14829" /db_xref="GOA:P94534" /db_xref="InterPro:IPR004017" /db_xref="InterPro:IPR009051" /db_xref="InterPro:IPR012257" /db_xref="InterPro:IPR017896" /db_xref="InterPro:IPR017900" /db_xref="SubtiList:BG12321" /db_xref="UniProtKB/Swiss-Prot:P94534" /translation="MTTEKEMKQIQNEFKERMDEGELLNCMRCGFCLPSCPTYIESGF QETHSPRGRIALMKAVADGMIEPDEDVERSLSLCLGCRACEPVCPSGVKYGQLLEEAR DIIHQNKKHSLGERVMRKTAFHELFPHQNRMRSAVSLIGLYQRSGLQTAVRKSGMLRV LPEHLRTMEAVLPDVPKSKDMKHRPRFLPSIGPMKKRVAFFSGCLMDTMFLPTNNATL KLLQLAGCDIVIPPEQACCGALHGHSGEKNTGKELAKQNIAAFEALDVDAVITNAGGC GAFLTEYDHLLKDDPEWSERAAAFVQKLKDFSSVLVELDFHQMDLALETPQVVTYQDS CHLRNVMHTSLEPRQLLKSIKGAEFKEMEKADSCCGSAGIYNIVEVEMSMKILDSKMA AVKATEAILIVTANPGCLLQMKLGIEREGLSGKVRAVHLADLLLEAAGHKTS*" gene 2800192..2801526 /gene="glcF" /locus_tag="BSU_28690" /old_locus_tag="BSU28690" downshifts 2801524 /Source="Nicolas_upshifts" /id="D1468" /incds=0 /nref=48 /ntot=148 /MaxReadThrough="3.07756" /MaxDrop="5.25031" /score="4.55188138" /energy="-14.3" /TU="U2220" /idTUdmin="U2220" /TUdmin="-181" /isTUend="FALSE" downshifts complement(2801563) /Source="Nicolas_upshifts" /id="D1469" /incds=0 /nref=27 /ntot=221 /MaxReadThrough="1.51397" /MaxDrop="5.34865" /score="-5.71907967" /energy="-14.3" /TU="NA" /idTUdmin="U2222" /TUdmin="-2" /isTUend="TRUE" CDS complement(2801565..2801807) /gene="ysfE" /locus_tag="BSU_28700" /old_locus_tag="BSU28700" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_390748.1" /db_xref="EnsemblGenomes-Gn:BSU28700" /db_xref="EnsemblGenomes-Tr:CAB14830" /db_xref="InterPro:IPR025870" /db_xref="InterPro:IPR029068" /db_xref="SubtiList:BG12322" /db_xref="UniProtKB/Swiss-Prot:P94533" /translation="MALNTRESARDITALDIPDTSASNTFEIGFVTENVEAVIKRMRE QGVSIIGEPKVKPWGQTVAYIADPDGHYIEICSPME*" gene complement(2801565..2801807) /gene="ysfE" /locus_tag="BSU_28700" /old_locus_tag="BSU28700" S_feature complement(2801808..2801979) /Source="Nicolas_S_feature" /locus_tag="new_2936210_2936381_c" /HighExp="Sw, M0t90, M40t90, M9-stat, T2.0H, BC, T0.30H, Lbstat, T2.30H, T3.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigH, SigA" /TUshortPSig="0.999, 0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S1084" CDS complement(2801867..2802037) /locus_tag="BSU_28709" /old_locus_tag="BSU28709" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_009513996.1" /translation="MGADVERSELKDGSIYTGLEGLLKMLRGVGNESINEISYSIRIG QQAGYSFFTGIF*" gene complement(2801867..2802037) /locus_tag="BSU_28709" /old_locus_tag="BSU28709" CDS complement(2801980..2803776) /gene="cstA" /locus_tag="BSU_28710" /old_locus_tag="BSU28710" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:15849754, 16850406, 1848300, 17320232, 19682248" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15849754, 16850406, 1848300, 17320232, 19682248; Product type ph: phenotype" /codon_start=1 /transl_table=11 /product="carbon starvation-induced membrane protein" /protein_id="NP_390749.2" /db_xref="EnsemblGenomes-Gn:BSU28710" /db_xref="EnsemblGenomes-Tr:CAB14831" /db_xref="GOA:P94532" /db_xref="InterPro:IPR003706" /db_xref="InterPro:IPR025299" /db_xref="SubtiList:BG11924" /db_xref="UniProtKB/Swiss-Prot:P94532" /translation="MNAVTIVIASMCILAIAYRLYGTFMMVKVLKVNDDKPTPAHALE DGKDYVPTNKWVSFGHHFAAIAAAGPLVGPILAAQFGYLPGLLWLLIGAVIGGAVHDI VVLFASMRKNGKSLSEVAKDELGPVAGFCTGLSMLFIITITMAGLSMVVLHALERNPW GTFAVGITIPIAMGVGLFYKKTGNLKLASTVGFLFLMAGVFIGPWVQTTALGDFLTLD TKTLAIALPVYAFFAAALPVWLLLAPRDYLSSFMKIGVFIALIVGVFVVNPSIPFPAF TEFVKGGGPVLAGPVWPFISITIACGAISGFHAFVGSGTTPKMLNKWSDMKPVAFGAM LVECLVGIMALIAATALQPADYFAINSTPEVFRTLGMNVVHLPELSGEIGLDLEGRTG GAVTLAVGMTYIFTGMPFFSHLASYFFQFVIMFEAVFILTAIDAGTRVARYLIQDFFG EVYKPLKKTDWIPGSVFASALACLMWGYLLYSGDIGSIWALFGVSNQLMASVGLIIGA TIVLKIADKRRYILTCLIPLAYLYVTVNYAGYWMVRNVYLNPEAAGYSVLNGVLSIIM LVLGFIIIVAAVKKWAQMWKDPSLRMEASIPG*" gene complement(2801980..2803776) /gene="cstA" /locus_tag="BSU_28710" /old_locus_tag="BSU28710" promotor_-10 complement(2802082..2802100) /Source="Nicolas_upshift_promotors" /id="U2222" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=3197 /SigmaFactorBS="ctattggatggtgcgcaatgtgtatctcaatcctgaagcaGC AGGATATagtgtattgaaTGGCGTATTATCTATCATCatgctggtgttaggcttcatc a" /listShort="S1084, ysfE" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2802100) /Source="Nicolas_upshifts" /id="U2222" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=3197 /SigmaFactorBS="ctattggatggtgcgcaatgtgtatctcaatcctgaagcaGC AGGATATagtgtattgaaTGGCGTATTATCTATCATCatgctggtgttaggcttcatc a" /listShort="S1084, ysfE" /GFF_Attribute="listLong" promotor_-35 complement(2802112..2802120) /Source="Nicolas_upshift_promotors" /id="U2222" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=3197 /SigmaFactorBS="ctattggatggtgcgcaatgtgtatctcaatcctgaagcaGC AGGATATagtgtattgaaTGGCGTATTATCTATCATCatgctggtgttaggcttcatc a" /listShort="S1084, ysfE" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 2803773 /Source="Nicolas_upshifts" /id="D1470" /incds=0 /nref=4 /ntot=49 /MaxReadThrough="0.92122" /MaxDrop="3.18629" /score="12.2066828" /energy="-15.2" /TU="NA" /idTUdmin="U2220" /TUdmin=2068 /isTUend="FALSE" promotor_-10 complement(2803801..2803820) /Source="Nicolas_upshift_promotors" /id="U2223" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.511488511488511" /psig="0.999000999001" /xcortree=369 /SigmaFactorBS="ccattccagccggctttttgtataggaaaaAATGACCgcttt tcaccatgaAATTATGATATATTTATGAAaaacagaaaaggggatgggagaaaatgaa t" /listShort="cstA, S1084, ysfE" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2803811) /Source="Nicolas_upshifts" /id="U2223" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.511488511488511" /psig="0.999000999001" /xcortree=369 /SigmaFactorBS="ccattccagccggctttttgtataggaaaaAATGACCgcttt tcaccatgaAATTATGATATATTTATGAAaaacagaaaaggggatgggagaaaatgaa t" /listShort="cstA, S1084, ysfE" /GFF_Attribute="listLong" promotor_-35 complement(2803835..2803841) /Source="Nicolas_upshift_promotors" /id="U2223" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.511488511488511" /psig="0.999000999001" /xcortree=369 /SigmaFactorBS="ccattccagccggctttttgtataggaaaaAATGACCgcttt tcaccatgaAATTATGATATATTTATGAAaaacagaaaaggggatgggagaaaatgaa t" /listShort="cstA, S1084, ysfE" /GFF_Attribute="listLong" /label="promotor_-35" S_feature complement(2803871..2803927) /Source="Nicolas_S_feature" /locus_tag="new_2938273_2938329_c" /HighExp="BC, Sw, M40t90, T1.30H, M0t90, T1.0H, T0.30H, Lbstat, T2.30H, M9-stat" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="NA" /TUshortPSig="NA" /TUlongSig="NA" /TUlongPSig="NA" /label="S1085" downshifts complement(2803895) /Source="Nicolas_upshifts" /id="D1471" /incds=0 /nref=12 /ntot=40 /MaxReadThrough="0.655710000000001" /MaxDrop="5.03461" /score="9.68754272" /energy="-10.5" /TU="NA" /idTUdmin="U2224" /TUdmin="-2" /isTUend="TRUE" CDS complement(2803928..2805430) /gene="abfA" /locus_tag="BSU_28720" /old_locus_tag="BSU28720" /EC_number="3.2.1.55" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:10417639, 11418559, 12777810, 14973026, 16233670, 18757805" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10417639, 11418559, 12777810, 14973026, 16233670, 18757805; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="alpha-L-arabinofuranosidase" /protein_id="NP_390750.2" /db_xref="EnsemblGenomes-Gn:BSU28720" /db_xref="EnsemblGenomes-Tr:CAB14832" /db_xref="GOA:P94531" /db_xref="InterPro:IPR010720" /db_xref="InterPro:IPR017853" /db_xref="SubtiList:BG11900" /db_xref="UniProtKB/Swiss-Prot:P94531" /translation="MKKARMIVDKEYKIGEVDKRIYGSFIEHMGRAVYEGIYEPDHPE ADEDGFRKDVQSLIKELQVPIIRYPGGNFLSGYNWEDGVGPVENRPRRLDLAWQTTET NEVGTNEFLSWAKKVNTEVNMAVNLGTRGIDAARNLVEYCNHPKGSYWSDLRRSHGYE QPYGIKTWCLGNEMDGPWQIGHKTADEYGRLAAETAKVMKWVDPSIELVACGSSNSGM PTFIDWEAKVLEHTYEHVDYISLHTYYGNRDNNLPNYLARSMDLDHFIKSVAATCDYV KAKTRSKKTINLSLDEWNVWYHSNEADKKVEPWITARPILEDIYNFEDALLVGSLLIT MLQHADRVKIACLAQLVNVIAPIMTEKGGEAWRQPIFYPYMHASVYGRGESLKPLISS PKYDCSDFTDVPYVDAAVVYSEEEETLTIFAVNKAEDQMETEISLRGFESYQIAEHIV LEHQDIKATNQHNRKNVVPHSNGSSSVSENGLTAHFTPLSWNVIRLKKQS*" gene complement(2803928..2805430) /gene="abfA" /locus_tag="BSU_28720" /old_locus_tag="BSU28720" downshifts complement(2805301) /Source="Nicolas_upshifts" /id="D1472" /incds=1 /nref=7 /ntot=15 /MaxReadThrough="3.81491" /MaxDrop="6.33773" /score="2.73497974" /energy="-14.2" /TU="U2224,U2225" /idTUdmin="U2224" /TUdmin="-1408" /isTUend="FALSE" promotor_no_box complement(2805405..2805505) /Source="Nicolas_upshift_promotors" /id="U2224" /multdbtbs="-" /comp="M21" /sig="Sig-" /pcomp="0.608391608391608" /psig="0.017982017982018" /xcortree=1474 /SigmaFactorBS="ttgtttttccaaaagtactttatctccggcctgacggtaggg ggagtcaaaggttaatgaaggaggaaacgtgtgatgaaaaaagcgcgaatgattgtag a" /listShort="abfA" /GFF_Attribute="listLong" /label="promotor_no_box" upshifts complement(2805445) /Source="Nicolas_upshifts" /id="U2224" /multdbtbs="-" /comp="M21" /sig="Sig-" /pcomp="0.608391608391608" /psig="0.017982017982018" /xcortree=1474 /SigmaFactorBS="ttgtttttccaaaagtactttatctccggcctgacggtaggg ggagtcaaaggttaatgaaggaggaaacgtgtgatgaaaaaagcgcgaatgattgtag a" /listShort="abfA" /GFF_Attribute="listLong" CDS complement(2805449..2806294) /gene="araQ" /locus_tag="BSU_28730" /old_locus_tag="BSU28730" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:9084180, 10417639, 11418559, 14973026, 15849754, 16850406, 22720735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9084180, 10417639, 11418559, 14973026, 15849754, 16850406, 22720735; Product type t: transporter" /codon_start=1 /transl_table=11 /product="arabinose/arabinan permease" /protein_id="NP_390751.2" /db_xref="EnsemblGenomes-Gn:BSU28730" /db_xref="EnsemblGenomes-Tr:CAB14833" /db_xref="GOA:P94530" /db_xref="InterPro:IPR000515" /db_xref="InterPro:IPR035906" /db_xref="SubtiList:BG11912" /db_xref="UniProtKB/Swiss-Prot:P94530" /translation="MLRHSPQFSVYRIALTLFFMMLSLLYLFPIFCLLLGSLKPSSEL LRVGLNLDIDPKVMSFDNYTFLFNGGSIYFKWFFNSLVLGLFTTVLTLFFSSMIGYGL AVYDFKGRNIIFVLVLIIMMVPLEVMMLPLFKLTVGLHLIDSYTGVILPFIVSPVAVF FFRQYALGLPRDLLDSARMDGCTEFGIFFRIMAPLMKPAFGAMIILQSLNSWNNFLWP LIVLRSKEMFTLPIGLSSLLSPYGNNYDMLISGSVFAILPVIIIFLFFQKYFISGLTV GGVKG*" gene complement(2805449..2806294) /gene="araQ" /locus_tag="BSU_28730" /old_locus_tag="BSU28730" CDS complement(2806295..2807236) /gene="araP" /locus_tag="BSU_28740" /old_locus_tag="BSU28740" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 9084180, 10417639, 11418559, 14973026, 15849754, 16850406, 22720735; Product type t: transporter" /codon_start=1 /transl_table=11 /product="arabinose/arabinan permease" /protein_id="NP_390752.1" /db_xref="EnsemblGenomes-Gn:BSU28740" /db_xref="EnsemblGenomes-Tr:CAB14834" /db_xref="GOA:P94529" /db_xref="InterPro:IPR000515" /db_xref="InterPro:IPR035277" /db_xref="InterPro:IPR035906" /db_xref="SubtiList:BG11911" /db_xref="UniProtKB/Swiss-Prot:P94529" /translation="MKPVKTGTVHPVPSAAKQSGWRDLFYSKKAAPYLFTAPFVLSFL VFFLYPIISVFIMSFQRILPGEVSFVGLSNYTALNNPTFYTALWNTLEYTFWTLIVLI PVPLLLAIFLNSKLVKFRNIFKSALFIPALTSTIVAGIIFRLIFGEMETSLANSILLK LGFSPQNWMNNEHTGMFLMVLLASWRWMGINILYFLAGLQNVPKELYEAADIDGANTM KKFLHITLPFLKPVTVYVLTISIIGGFRMFEESYVLWQNNSPGNIGLTLVGYLYQQGL AYNEMGYGAAIGIVLLIVILVVSLISLKLSGSFKGEG*" gene complement(2806295..2807236) /gene="araP" /locus_tag="BSU_28740" /old_locus_tag="BSU28740" CDS complement(2807272..2808573) /gene="araN" /locus_tag="BSU_28750" /old_locus_tag="BSU28750" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 9084180, 10417639, 11418559, 14973026, 15849754, 16850406, 22720735; Product type lp: lipoprotein" /codon_start=1 /transl_table=11 /product="sugar-binding lipoprotein" /protein_id="NP_390753.2" /db_xref="EnsemblGenomes-Gn:BSU28750" /db_xref="EnsemblGenomes-Tr:CAB14835" /db_xref="GOA:P94528" /db_xref="InterPro:IPR006059" /db_xref="SubtiList:BG11910" /db_xref="UniProtKB/Swiss-Prot:P94528" /translation="MKKMTVCFLVLMMLLTLVIAGCSAEKSSGKSGETELTFWTFNGL HEQFYVEMVKEWNKKYPDRKIKLNTVVYPYGQMHDNLSISLIAGEGVPDIADVELARF SNFLKGSDIPLADLTPLIEKDRDKFVEARLTLYSKNGKLYGLDTHVGTTVMFYNMDVM KKAGVNPDDIKTWDDYHKAGQKVRKVTGKPMGTVETNDSATFLSMISQQNSGYFDKNG KLILNNDTNVKTLQYLKDMINDKTMIPAPGGGHHSEEYYGFMNQGGAASVLMPIWYMG RFIDYMPDLKGKIAIRPLPAWKEGGDRSAGLGGTATVVPKQSKHVELAKEFLAFAKGS EEGNKKLWSVLGFDPLRWDVWSSKELKEKNKYTDYFQNGTGIFSVLLDIKDEINPIYL HEDFAKASDLVNRSVLFDALKSQQKTPKQALDRAAGELKQK*" gene complement(2807272..2808573) /gene="araN" /locus_tag="BSU_28750" /old_locus_tag="BSU28750" CDS complement(2808604..2809788) /gene="egsA" /locus_tag="BSU_28760" /old_locus_tag="BSU28760" /EC_number="1.1.1.261" /function="16.8: Protect" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:9084180, 9973362, 10417639, 11418559, 14973026, 18558723, 22720735, 27774041" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9084180, 9973362, 10417639, 11418559, 14973026, 18558723, 22720735, 27774041; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="sn-glycerol-1-phosphate dehydrogenase [NAD+] (catabolic)" /protein_id="NP_390754.1" /db_xref="EnsemblGenomes-Gn:BSU28760" /db_xref="EnsemblGenomes-Tr:CAB14836" /db_xref="GOA:P94527" /db_xref="InterPro:IPR023003" /db_xref="InterPro:IPR032837" /db_xref="SubtiList:BG11909" /db_xref="UniProtKB/Swiss-Prot:P94527" /translation="MNRIAADVQRAFENAGEKTLPIKVEEIVLGKQAADSLLDYVKRK NNQHIVLVCDANTHRIAGIDLENRLNQEGFQAECLIIPENEAGDVTADERSLIHVLIH TKQPTDVMIAVGSGTIHDIVRFAAFQRDLPFISYPTAPSVDGFTSAGAPIILYGTKTT IQTKAPSALFADLDLLKAAPQSMVAAGFGDMLGKITSLADWEISRHLAGEPYSPAGAK IVQEALAACIEHTEDIAMKTETGIRVLMESLLVSGLVMLALDHSRPASGGEHHISHWI EMELMEKKRPQILHGAKVGCAAVLLTDTYRKLAQDDGLNEFSPSRREAIQSAYQTLPR GEVLADWLRSAGGPAYFDEIGVGQDSVKNAFRHAHTLRDRCTGLRIINENKTLINHGL YE*" gene complement(2808604..2809788) /gene="egsA" /locus_tag="BSU_28760" /old_locus_tag="BSU28760" CDS complement(2809785..2810603) /gene="araL" /locus_tag="BSU_28770" /old_locus_tag="BSU28770" /EC_number="3.1.3.23" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:10417639, 11418559, 14973026, 21575135, 22720735, 25848029" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10417639, 11418559, 14973026, 21575135, 22720735, 25848029; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="glycolytic and pentose phosphate intermediates phosphatase" /protein_id="NP_390755.1" /db_xref="EnsemblGenomes-Gn:BSU28770" /db_xref="EnsemblGenomes-Tr:CAB14837" /db_xref="GOA:P94526" /db_xref="InterPro:IPR006357" /db_xref="InterPro:IPR023214" /db_xref="InterPro:IPR036412" /db_xref="SubtiList:BG11908" /db_xref="UniProtKB/Swiss-Prot:P94526" /translation="MRIMASHDTPVSPAGILIDLDGTVFRGNELIEGAREAIKTLRRM GKKIVFLSNRGNISRAMCRKKLLGAGIETDVNDIVLSSSVTAAFLKKHYRFSKVWVLG EQGLVDELRLAGVQNASEPKEADWLVISLHETLTYDDLNQAFQAAAGGARIIATNKDR SFPNEDGNAIDVAGMIGAIETSAQAKTELVVGKPSWLMAEAACTAMGLSAHECMIIGD SIESDIAMGKLYGMKSALVLTGSAKQGEQRLYTPDYVLDSIKDVTKLAEEGILI*" gene complement(2809785..2810603) /gene="araL" /locus_tag="BSU_28770" /old_locus_tag="BSU28770" CDS complement(2810581..2811270) /gene="araD" /locus_tag="BSU_28780" /old_locus_tag="BSU28780" /EC_number="5.1.3.4" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 10417639, 11418559, 11732895, 14973026, 22720735; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="L-ribulose-5-phosphate 4-epimerase" /protein_id="NP_390756.1" /db_xref="EnsemblGenomes-Gn:BSU28780" /db_xref="EnsemblGenomes-Tr:CAB14838" /db_xref="GOA:P94525" /db_xref="InterPro:IPR001303" /db_xref="InterPro:IPR004661" /db_xref="InterPro:IPR036409" /db_xref="SubtiList:BG11906" /db_xref="UniProtKB/Swiss-Prot:P94525" /translation="MLETLKKEVLAANLKLQEHQLVTFTWGNVSGIDREKERIVIKPS GVEYSDLTADDLVVLNLDGEVVEGSLKPSSDTPTHVYLYKAFPNIGGIVHTHSQWATS WAQSGRDIPPLGTTHADYFDSAIPCTREMYDEEIIHDYELNTGKVIAETFQHHNYEQV PGVLVNNHGPFCWGTDALNAIHNAVVLETVAEMAYHSIMLNKDVTPINTVLHEKHFYR KHGANAYYGQS*" gene complement(2810581..2811270) /gene="araD" /locus_tag="BSU_28780" /old_locus_tag="BSU28780" CDS complement(2811287..2812969) /gene="araB" /locus_tag="BSU_28790" /old_locus_tag="BSU28790" /EC_number="2.7.1.16" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 173711, 4910050, 10417639, 11418559, 14973026, 22720735; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="L-ribulokinase" /protein_id="NP_390757.1" /db_xref="EnsemblGenomes-Gn:BSU28790" /db_xref="EnsemblGenomes-Tr:CAB14839" /db_xref="GOA:P94524" /db_xref="InterPro:IPR000577" /db_xref="InterPro:IPR005929" /db_xref="InterPro:IPR018483" /db_xref="InterPro:IPR018484" /db_xref="InterPro:IPR018485" /db_xref="SubtiList:BG11905" /db_xref="UniProtKB/Swiss-Prot:P94524" /translation="MAYTIGVDFGTLSGRAVLVHVQTGEELAAAVKEYRHAVIDTVLP KTGQKLPRDWALQHPADYLEVLETTIPSLLEQTGVDPKDIIGIGIDFTACTILPIDSS GQPLCMLPEYEEEPHSYVKLWKHHAAQKHADRLNQIAEEEGEAFLQRYGGKISSEWMI PKVMQIAEEAPHIYEAADRIIEAADWIVYQLCGSLKRSNCTAGYKAMWSEKAGYPSDD FFEKLNPSMKTITKDKLSGSIHSVGEKAGSLTEKMAKLTGLLPGTAVAVANVDAHVSV PAVGITEPGKMLMIMGTSTCHVLLGEEVHIVPGMCGVVDNGILPGYAGYEAGQSCVGD HFDWFVKTCVPPAYQEEAKEKNIGVHELLSEKANHQAPGESGLLALDWWNGNRSTLVD ADLTGMLLGMTLLTKPEEIYRALVEATAYGTRMIIETFKESGVPIEELFAAGGIAEKN PFVMQIYADVTNMDIKISGSPQAPALGSAIFGALAAGKEKGGYDDIKKAAANMGKLKD ITYTPNAENAAVYEKLYAEYKELVHYFGKENHVMKRLKTIKNLQFSSAAKKN*" gene complement(2811287..2812969) /gene="araB" /locus_tag="BSU_28790" /old_locus_tag="BSU28790" CDS complement(2812983..2814473) /gene="araA" /locus_tag="BSU_28800" /old_locus_tag="BSU28800" /EC_number="5.3.1.4" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:10417639, 10669396, 11418559, 14973026, 18263741" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10417639, 10669396, 11418559, 14973026, 18263741; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="L-arabinose isomerase" /protein_id="NP_390758.2" /db_xref="EnsemblGenomes-Gn:BSU28800" /db_xref="EnsemblGenomes-Tr:CAB14840" /db_xref="GOA:P94523" /db_xref="InterPro:IPR003762" /db_xref="InterPro:IPR004216" /db_xref="InterPro:IPR009015" /db_xref="InterPro:IPR024664" /db_xref="SubtiList:BG11904" /db_xref="UniProtKB/Swiss-Prot:P94523" /translation="MLQTKDYEFWFVTGSQHLYGEETLELVDQHAKSICEGLSGISSR YKITHKPVVTSPETIRELLREAEYSETCAGIITWMHTFSPAKMWIEGLSSYQKPLMHL HTQYNRDIPWGTIDMDFMNSNQSAHGDREYGYINSRMGLSRKVIAGYWDDEEVKKEMS QWMDTAAALNESRHIKVARFGDNMRHVAVTDGDKVGAHIQFGWQVDGYGIGDLVEVMD RITDDEVDTLYAEYDRLYVISEETKRDEAKVASIKEQAKIELGLTAFLEQGGYTAFTT SFEVLHGMKQLPGLAVQRLMEKGYGFAGEGDWKTAALVRMMKIMAKGKRTSFMEDYTY HFEPGNEMILGSHMLEVCPTVALDQPKIEVHSLSIGGKEDPARLVFNGISGSAIQASI VDIGGRFRLVLNEVNGQEIEKDMPNLPVARVLWKPEPSLKTAAEAWILAGGAHHTCLS YELTAEQMLDWAEMAGIESVLISRDTTIHKLKHELKWNEALYRLQK*" gene complement(2812983..2814473) /gene="araA" /locus_tag="BSU_28800" /old_locus_tag="BSU28800" promotor_-10 complement(2814566..2814585) /Source="Nicolas_upshift_promotors" /id="U2225" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.978021978021978" /psig=1 /xcortree=1574 /SigmaFactorBS="tgcccccggctttttttaaaagaaaaGATTGACAgtataata gtcaatTACTATAATAAAATTGTTCGtacaaatatttatttataggtttattttctat c" /listShort="araA, araB, araD, araL, araM, araN, araP, araQ, abfA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2814573) /Source="Nicolas_upshifts" /id="U2225" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.978021978021978" /psig=1 /xcortree=1574 /SigmaFactorBS="tgcccccggctttttttaaaagaaaaGATTGACAgtataata gtcaatTACTATAATAAAATTGTTCGtacaaatatttatttataggtttattttctat c" /listShort="araA, araB, araD, araL, araM, araN, araP, araQ, abfA" /GFF_Attribute="listLong" S_feature complement(2814575..2814650) /Source="Nicolas_S_feature" /locus_tag="new_2948977_2949052_c" /HighExp="M9-stat, T1.30H, T2.0H, T2.30H, T3.0H, T4.0H, T3.30H, T1.0H, BC, M0t90" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.995" /TUlongSig="SigA" /TUlongPSig="0.993" /label="S1086" promotor_-35 complement(2814600..2814607) /Source="Nicolas_upshift_promotors" /id="U2225" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.978021978021978" /psig=1 /xcortree=1574 /SigmaFactorBS="tgcccccggctttttttaaaagaaaaGATTGACAgtataata gtcaatTACTATAATAAAATTGTTCGtacaaatatttatttataggtttattttctat c" /listShort="araA, araB, araD, araL, araM, araN, araP, araQ, abfA" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2814651..2815622) /gene="abnA" /locus_tag="BSU_28810" /old_locus_tag="BSU28810" /EC_number="3.2.1.99" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:14973026, 15556708, 17827291, 25355936" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 14973026, 15556708, 17827291, 25355936; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="arabinan-endo-1,5-alpha-L-arabinase" /protein_id="NP_390759.2" /db_xref="EnsemblGenomes-Gn:BSU28810" /db_xref="EnsemblGenomes-Tr:CAB14841" /db_xref="GOA:P94522" /db_xref="InterPro:IPR006710" /db_xref="InterPro:IPR016840" /db_xref="InterPro:IPR023296" /db_xref="PDB:1UV4" /db_xref="SubtiList:BG11901" /db_xref="UniProtKB/Swiss-Prot:P94522" /translation="MKKKKTWKRFLHFSSAALAAGLIFTSAAPAEAAFWGASNELLHD PTMIKEGSSWYALGTGLTEERGLRVLKSSDAKNWTVQKSIFTTPLSWWSNYVPNYGQN QWAPDIQYYNGKYWLYYSVSSFGSNTSAIGLASSTSISSGGWKDEGLVIRSTSSNNYN AIDPELTFDKDGNPWLAFGSFWSGIKLTKLDKSTMKPTGSLYSIAARPNNGGALEAPT LTYQNGYYYLMVSFDKCCDGVNSTYKIAYGRSKSITGPYLDKSGKSMLEGGGTILDSG NDQWKGPGGQDIVNGNILVRHAYDANDNGIPKLLINDLNWSSGWPSY*" gene complement(2814651..2815622) /gene="abnA" /locus_tag="BSU_28810" /old_locus_tag="BSU28810" S_feature complement(2815623..2815751) /Source="Nicolas_S_feature" /locus_tag="new_2950025_2950153_c" /HighExp="M9-stat, BC, T2.0H, T2.30H, T3.0H, S8, T1.30H, T3.30H, M0t90, T4.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.995" /TUlongSig="SigA" /TUlongPSig="0.993" /label="S1087" promotor_-10 complement(2815736..2815755) /Source="Nicolas_upshift_promotors" /id="U2226" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.504495504495505" /psig="0.995004995004995" /xcortree=359 /SigmaFactorBS="gaagaatccgcctattgaggtggattctatttttttgtCTGT acaaattacagcatAGTGACTACAATAAAGGGGAtaccgaaaatttcctgaacatgac g" /listShort="S1087, abnA, S1086, araA, araB, araD, araL, araM, araN" /listLong="araP, araQ, abfA" /label="promotor_-10" upshifts complement(2815751) /Source="Nicolas_upshifts" /id="U2226" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.504495504495505" /psig="0.995004995004995" /xcortree=359 /SigmaFactorBS="gaagaatccgcctattgaggtggattctatttttttgtCTGT acaaattacagcatAGTGACTACAATAAAGGGGAtaccgaaaatttcctgaacatgac g" /listShort="S1087, abnA, S1086, araA, araB, araD, araL, araM, araN" /listLong="araP, araQ, abfA" promotor_-35 complement(2815770..2815773) /Source="Nicolas_upshift_promotors" /id="U2226" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.504495504495505" /psig="0.995004995004995" /xcortree=359 /SigmaFactorBS="gaagaatccgcctattgaggtggattctatttttttgtCTGT acaaattacagcatAGTGACTACAATAAAGGGGAtaccgaaaatttcctgaacatgac g" /listShort="S1087, abnA, S1086, araA, araB, araD, araL, araM, araN" /listLong="araP, araQ, abfA" /label="promotor_-35" CDS complement(2815819..2816904) /gene="frvX" /locus_tag="BSU_28820" /old_locus_tag="BSU28820" /EC_number="3.4.11.-" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2b: Function from indirect experimental evidences (e.g. phenotypes); PubMedId: 15375159, 16021622; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative fructose-lysine aminopeptidase" /protein_id="NP_390760.1" /db_xref="EnsemblGenomes-Gn:BSU28820" /db_xref="EnsemblGenomes-Tr:CAB14842" /db_xref="GOA:P94521" /db_xref="InterPro:IPR008007" /db_xref="InterPro:IPR023367" /db_xref="PDB:1VHE" /db_xref="SubtiList:BG12317" /db_xref="UniProtKB/Swiss-Prot:P94521" /translation="MAKLDETLTMLKDLTDAKGIPGNEREVRQVMKSYIEPFADEVTT DRLGSLIAKKTGAENGPKIMIAGHLDEVGFMVTQITDKGFIRFQTVGGWWAQVMLAQR VTIVTKKGEITGVIGSKPPHILSPEARKKSVEIKDMFIDIGASSREEALEWGVLPGDM IVPHFEFTVMNNEKFLLAKAWDNRIGCAIAIDVLRNLQNTDHPNIVYGVGTVQEEVGL RGAKTAAHTIQPDIAFGVDVGIAGDTPGISEKEAQSKMGKGPQIIVYDASMVSHKGLR DAVVATAEEAGIPYQFDAIAGGGTDSGAIHLTANGVPALSITIATRYIHTHAAMLHRD DYENAVKLITEVIKKLDRKTVDEITYQ*" gene complement(2815819..2816904) /gene="frvX" /locus_tag="BSU_28820" /old_locus_tag="BSU28820" downshifts complement(2815833) /Source="Nicolas_upshifts" /id="D1473" /incds=0 /nref=233 /ntot=262 /MaxReadThrough="3.55686" /MaxDrop="6.91328" /score="-0.475558157" /energy="-9.9" /TU="U2227" /idTUdmin="U2227" /TUdmin="-66" /isTUend="FALSE" promotor_-10 complement(2816930..2816949) /Source="Nicolas_upshift_promotors" /id="U2227" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.97902097902098" /psig="0.993006993006993" /xcortree=2217 /SigmaFactorBS="aaaagaaagctgtaaaaacatatacccgattttcaagtgaaa TAGTCGTAtggttagcgccatgTTTTGTATAATAAGAATGCAggactgatgaaggagg g" /listShort="ysdC" /listLong="S1087, abnA, S1086, araA, araB, araD, araL, araM, araN, araP, araQ, abfA" /label="promotor_-10" upshifts complement(2816953) /Source="Nicolas_upshifts" /id="U2227" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.97902097902098" /psig="0.993006993006993" /xcortree=2217 /SigmaFactorBS="aaaagaaagctgtaaaaacatatacccgattttcaagtgaaa TAGTCGTAtggttagcgccatgTTTTGTATAATAAGAATGCAggactgatgaaggagg g" /listShort="ysdC" /listLong="S1087, abnA, S1086, araA, araB, araD, araL, araM, araN, araP, araQ, abfA" promotor_-35 complement(2816964..2816971) /Source="Nicolas_upshift_promotors" /id="U2227" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.97902097902098" /psig="0.993006993006993" /xcortree=2217 /SigmaFactorBS="aaaagaaagctgtaaaaacatatacccgattttcaagtgaaa TAGTCGTAtggttagcgccatgTTTTGTATAATAAGAATGCAggactgatgaaggagg g" /listShort="ysdC" /listLong="S1087, abnA, S1086, araA, araB, araD, araL, araM, araN, araP, araQ, abfA" /label="promotor_-35" promotor_-35 2817022..2817031 /Source="Nicolas_upshift_promotors" /id="U2228" /multdbtbs="SigW" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1686 /SigmaFactorBS="cttgaaaatcgggtatatgtttttacagctttcttttagaaa aagTGAAACCTTTttctatgctttTCGTATTACATCAGATcatcaccataagggaggt g" /listShort="ysdB, S1088, yscB" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 2817037 /Source="Nicolas_upshifts" /id="U2228" /multdbtbs="SigW" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1686 /SigmaFactorBS="cttgaaaatcgggtatatgtttttacagctttcttttagaaa aagTGAAACCTTTttctatgctttTCGTATTACATCAGATcatcaccataagggaggt g" /listShort="ysdB, S1088, yscB" /GFF_Attribute="listLong" promotor_-10 2817043..2817058 /Source="Nicolas_upshift_promotors" /id="U2228" /multdbtbs="SigW" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1686 /SigmaFactorBS="cttgaaaatcgggtatatgtttttacagctttcttttagaaa aagTGAAACCTTTttctatgctttTCGTATTACATCAGATcatcaccataagggaggt g" /listShort="ysdB, S1088, yscB" /GFF_Attribute="listLong" /label="promotor_-10" CDS 2817088..2817480 /gene="ysdB" /locus_tag="BSU_28830" /old_locus_tag="BSU28830" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 10960106, 23155385" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_390761.1" /db_xref="EnsemblGenomes-Gn:BSU28830" /db_xref="EnsemblGenomes-Tr:CAB14843" /db_xref="GOA:P94520" /db_xref="SubtiList:BG12316" /db_xref="UniProtKB/Swiss-Prot:P94520" /translation="MFVMVLRIILLALFAYCIYAVVKYVANPKRRLKLAQSKEHFYII DEQNNTRKNFQLTYKGVLFEGEKHIPSKDHPLFIHTIFVWTESPEKLKHFSAKDFENI EEKVLERYPNCKIDWDQPIKLAKKAEER*" gene 2817088..2817480 /gene="ysdB" /locus_tag="BSU_28830" /old_locus_tag="BSU28830" downshifts 2817451 /Source="Nicolas_upshifts" /id="D1474" /incds=0 /nref=86 /ntot=229 /MaxReadThrough="5.09744" /MaxDrop="4.57118" /score="13.4996084" /energy="-15.8" /TU="U2228" /idTUdmin="U2228" /TUdmin="-2112" /isTUend="FALSE" S_feature 2817496..2817802 /Source="Nicolas_S_feature" /locus_tag="new_2951898_2952204" /HighExp="Etha, M9-stat, T0.30H, T1.30H, T1.0H, T2.0H, T2.30H, S8, T3.30H, Salt" /AntisenseName="ysdA" /AntisenseCor="-0.31305612685159701" /AntisenseRegPval="-6.8" /CDS_PredictionProba="NA" /TUshortSig="SigWXY" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1088" CDS complement(2817496..2817765) /gene="ysdA" /locus_tag="BSU_28840" /old_locus_tag="BSU28840" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 17289755; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative membrane component" /protein_id="NP_390762.1" /db_xref="EnsemblGenomes-Gn:BSU28840" /db_xref="EnsemblGenomes-Tr:CAB14844" /db_xref="GOA:P94519" /db_xref="InterPro:IPR010718" /db_xref="SubtiList:BG12315" /db_xref="UniProtKB/Swiss-Prot:P94519" /translation="MIIAAYLVLINLCGFWVMGIDKRKAQQHKWRISEDRLWLIAIVF GALGVWLGMQTFRHKTKHASFKYGVPLLLVIEAILIAIYYSPFDL*" gene complement(2817496..2817765) /gene="ysdA" /locus_tag="BSU_28840" /old_locus_tag="BSU28840" downshifts complement(2817512) /Source="Nicolas_upshifts" /id="D1475" /incds=0 /nref=6 /ntot=206 /MaxReadThrough="2.53274" /MaxDrop="3.80421" /score="20.1281719" /energy="-14" /TU="U2229" /idTUdmin="U2230" /TUdmin="-7" /isTUend="TRUE" downshifts complement(2817681) /Source="Nicolas_upshifts" /id="D1476" /incds=1 /nref=1 /ntot=37 /MaxReadThrough="4.90568" /MaxDrop="2.19601" /score="25.5196116" /energy="-14.1" /TU="U2229,U2230" /idTUdmin="U2230" /TUdmin="-176" /isTUend="FALSE" downshifts 2817759 /Source="Nicolas_upshifts" /id="D1477" /incds=0 /nref=8 /ntot=135 /MaxReadThrough="4.08794" /MaxDrop="3.37039" /score="13.4996084" /energy="-15.8" /TU="U2228" /idTUdmin="U2228" /TUdmin="-1804" /isTUend="FALSE" CDS complement(2817822..2818181) /gene="rplT" /locus_tag="BSU_28850" /old_locus_tag="BSU28850" /function="16.2: Construct biomass (Anabolism)" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:12682299, 17289755, 21843271, 23611891" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12682299, 17289755, 21843271, 23611891; Product type s: structure" /codon_start=1 /transl_table=11 /product="ribosomal protein L20" /protein_id="NP_390763.1" /db_xref="EnsemblGenomes-Gn:BSU28850" /db_xref="EnsemblGenomes-Tr:CAB14845" /db_xref="GOA:P55873" /db_xref="InterPro:IPR005813" /db_xref="InterPro:IPR035566" /db_xref="PDB:3J3V" /db_xref="PDB:3J3W" /db_xref="PDB:3J9W" /db_xref="PDB:5NJT" /db_xref="SubtiList:BG11971" /db_xref="UniProtKB/Swiss-Prot:P55873" /translation="MPRVKGGTVTRKRRKKVLKLAKGYFGSKHTLYKVANQQVMKSGN YAFRDRRQKKRDFRKLWITRINAAARMNGLSYSRLMHGLKLSGIEVNRKMLADLAVND LTAFNQLADAAKAQLNK*" gene complement(2817822..2818181) /gene="rplT" /locus_tag="BSU_28850" /old_locus_tag="BSU28850" downshifts complement(2817835) /Source="Nicolas_upshifts" /id="D1478" /incds=0 /nref=260 /ntot=268 /MaxReadThrough="5.94351" /MaxDrop="6.27682" /score="25.5196116" /energy="-14.1" /TU="U2229,U2230" /idTUdmin="U2230" /TUdmin="-330" /isTUend="FALSE" CDS complement(2818213..2818413) /gene="rpmI" /locus_tag="BSU_28860" /old_locus_tag="BSU28860" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:8722036, 12682299, 17289755, 21843271, 23002217, 23611891, 24335279" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8722036, 12682299, 17289755, 21843271, 23002217, 23611891, 24335279; Product type s: structure" /codon_start=1 /transl_table=11 /product="ribosomal protein L35" /protein_id="NP_390764.1" /db_xref="EnsemblGenomes-Gn:BSU28860" /db_xref="EnsemblGenomes-Tr:CAB14846" /db_xref="GOA:P55874" /db_xref="InterPro:IPR001706" /db_xref="InterPro:IPR018265" /db_xref="InterPro:IPR021137" /db_xref="InterPro:IPR037229" /db_xref="PDB:3J9W" /db_xref="PDB:5NJT" /db_xref="SubtiList:BG11972" /db_xref="UniProtKB/Swiss-Prot:P55874" /translation="MPKMKTHRGSAKRFKKTGSGKLKRSHAYTSHLFANKSQKQKRKL RKSAVVSAGDFKRIKQMLANIK*" gene complement(2818213..2818413) /gene="rpmI" /locus_tag="BSU_28860" /old_locus_tag="BSU28860" CDS complement(2818426..2818947) /gene="infC" /locus_tag="BSU_28870" /old_locus_tag="BSU28870" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:12682299, 17289755, 21843271, 22720735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12682299, 17289755, 21843271, 22720735; Product type f: factor" /codon_start=1 /transl_table=11 /product="initiation factor IF-3" /protein_id="NP_390765.1" /db_xref="EnsemblGenomes-Gn:BSU28870" /db_xref="EnsemblGenomes-Tr:CAB14847" /db_xref="GOA:P55872" /db_xref="InterPro:IPR001288" /db_xref="InterPro:IPR019813" /db_xref="InterPro:IPR019814" /db_xref="InterPro:IPR019815" /db_xref="InterPro:IPR036787" /db_xref="InterPro:IPR036788" /db_xref="SubtiList:BG11944" /db_xref="UniProtKB/Swiss-Prot:P55872" /translation="MISKDQLVNEGIRAREVRLIGQNGDQLGIKSRQEALEIAGRANL DLVLVAANAKPPVCRIMDYGKFRFEQQKKEKEARKNQKIINLKEVRLSPTIDEHDFNT KLRNAIKFLEKGDKVKASIRFKGRAITHKEIGQRVLDRFSEACAEVATVETKPKMDGR SMFLMLAPKNEKQ*" gene complement(2818426..2818947) /gene="infC" /locus_tag="BSU_28870" /old_locus_tag="BSU28870" misc_RNA complement(2819009..2819148) /locus_tag="BSU_misc_RNA_47" /product="mRNA L20_leader attenuator sequence" /experiment="publication(s) with functional evidences, PMID:17289755, 23611891" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 17289755, 23611891" gene complement(2819009..2819148) /locus_tag="BSU_misc_RNA_47" promotor_-10 complement(2819145..2819164) /Source="Nicolas_upshift_promotors" /id="U2229" /multdbtbs="SigA" /comp="M17" /sig="SigA" /pcomp="0.768231768231768" /psig=1 /xcortree=2647 /SigmaFactorBS="caatgtaaaagttgttccggataagtcgtcCTTGACTAaaga tccggtattGTGTAGAATAGTTATTGAATtgaatataaatcacaagcagaagcacccg c" /listShort="NA, infC, rpmI, rplT, ysdA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2819155) /Source="Nicolas_upshifts" /id="U2229" /multdbtbs="SigA" /comp="M17" /sig="SigA" /pcomp="0.768231768231768" /psig=1 /xcortree=2647 /SigmaFactorBS="caatgtaaaagttgttccggataagtcgtcCTTGACTAaaga tccggtattGTGTAGAATAGTTATTGAATtgaatataaatcacaagcagaagcacccg c" /listShort="NA, infC, rpmI, rplT, ysdA" /GFF_Attribute="listLong" S_feature complement(2819157..2819221) /Source="Nicolas_S_feature" /locus_tag="new_2953559_2953623_c" /HighExp="Paraq, G180, G150, G135, H2O2, LPh, C30, Oxctl, LBGexp, LBGstat" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1089" promotor_-35 complement(2819178..2819185) /Source="Nicolas_upshift_promotors" /id="U2229" /multdbtbs="SigA" /comp="M17" /sig="SigA" /pcomp="0.768231768231768" /psig=1 /xcortree=2647 /SigmaFactorBS="caatgtaaaagttgttccggataagtcgtcCTTGACTAaaga tccggtattGTGTAGAATAGTTATTGAATtgaatataaatcacaagcagaagcacccg c" /listShort="NA, infC, rpmI, rplT, ysdA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(2819203..2819222) /Source="Nicolas_upshift_promotors" /id="U2230" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.966033966033966" /psig=1 /xcortree=2590 /SigmaFactorBS="tttgtattctgggtggggatgaaagattttctttttctcTCT TGcgctcatagaaaaccCATGTTACAATGTAAAAGTTgttccggataagtcgtccttg a" /listShort="S1089, NA, infC, rpmI, rplT, ysdA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2819221) /Source="Nicolas_upshifts" /id="U2230" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.966033966033966" /psig=1 /xcortree=2590 /SigmaFactorBS="tttgtattctgggtggggatgaaagattttctttttctcTCT TGcgctcatagaaaaccCATGTTACAATGTAAAAGTTgttccggataagtcgtccttg a" /listShort="S1089, NA, infC, rpmI, rplT, ysdA" /GFF_Attribute="listLong" promotor_-35 complement(2819238..2819242) /Source="Nicolas_upshift_promotors" /id="U2230" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.966033966033966" /psig=1 /xcortree=2590 /SigmaFactorBS="tttgtattctgggtggggatgaaagattttctttttctcTCT TGcgctcatagaaaaccCATGTTACAATGTAAAAGTTgttccggataagtcgtccttg a" /listShort="S1089, NA, infC, rpmI, rplT, ysdA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 2819340..2819347 /Source="Nicolas_upshift_promotors" /id="U2231" /multdbtbs="SigD" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2840 /SigmaFactorBS="attacgcaatttacaacaaaaccaccgacaggaagaaatGTA AAACAaagttaatctctgACCGATATAAGGAGCAGAAgggagcctgacacatgaacaa a" /listShort="yscB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2819361..2819379 /Source="Nicolas_upshift_promotors" /id="U2231" /multdbtbs="SigD" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2840 /SigmaFactorBS="attacgcaatttacaacaaaaccaccgacaggaagaaatGTA AAACAaagttaatctctgACCGATATAAGGAGCAGAAgggagcctgacacatgaacaa a" /listShort="yscB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2819361 /Source="Nicolas_upshifts" /id="U2231" /multdbtbs="SigD" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2840 /SigmaFactorBS="attacgcaatttacaacaaaaccaccgacaggaagaaatGTA AAACAaagttaatctctgACCGATATAAGGAGCAGAAgggagcctgacacatgaacaa a" /listShort="yscB" /GFF_Attribute="listLong" CDS 2819393..2820058 /gene="yscB" /locus_tag="BSU_28890" /old_locus_tag="BSU28890" /function="14: Cell envelope" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15033535; Product type lp: lipoprotein" /codon_start=1 /transl_table=11 /product="putative lipoprotein" /protein_id="NP_390767.2" /db_xref="EnsemblGenomes-Gn:BSU28890" /db_xref="EnsemblGenomes-Tr:CAB14849" /db_xref="SubtiList:BG12314" /db_xref="UniProtKB/Swiss-Prot:P94517" /translation="MNKLIQLALFFTLMLTGCSNSSTSSESKVETTVKTTAAFPQKEL EKELKKLKPVSLDMKFESPLATELGKRKAKEEAEKQRQIAAEKKLEKEREAKRKKQQE EKAERQRLAEQQAAERQRLAEAERQAELERQRQAAIQKEQKANAEKKRQSQAQRQQTE APSSNSQDPPSSSSQTDKTIQQPASELPDDDGYGYEERKKWHDDQVEWGIKQGYIDPE DAP*" gene 2819393..2820058 /gene="yscB" /locus_tag="BSU_28890" /old_locus_tag="BSU28890" downshifts 2820036 /Source="Nicolas_upshifts" /id="D1479" /incds=0 /nref=27 /ntot=178 /MaxReadThrough="2.51181" /MaxDrop="3.43861" /score="13.4996084" /energy="-15.8" /TU="NA" /idTUdmin="U2231" /TUdmin=0 /isTUend="TRUE" CDS complement(2820090..2820785) /gene="pftB" /locus_tag="BSU_28900" /old_locus_tag="BSU28900" /function="16.5: Explore" /function="16.6: Maintain" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:15126464, 15849754, 16850406, 17452642, 26060272, 26406329, 28974613" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15126464, 15849754, 16850406, 17452642, 26060272, 26406329, 28974613; Product type t: transporter" /codon_start=1 /transl_table=11 /product="pyruvate import system subunit B" /protein_id="NP_390768.1" /db_xref="EnsemblGenomes-Gn:BSU28900" /db_xref="EnsemblGenomes-Tr:CAB14850" /db_xref="GOA:P94516" /db_xref="InterPro:IPR007300" /db_xref="InterPro:IPR024891" /db_xref="SubtiList:BG12312" /db_xref="UniProtKB/Swiss-Prot:P94516" /translation="MESTMSPYFGIVVSLAAFGIGTFLFKKTKGFFLFTPLFVAMVLG IAFLKIGGFSYADYNNGGEIIKFFLEPATIAFAIPLYKQRDKLKKYWWQIMASIIAGS ICSVTIVYLLAKGIHLDSAVMKSMLPQAATTAIALPLSKGIGGISDITAFAVIFNAVI VYALGALFLKVFKVKNPISKGLALGTSGHALGVAVGIEMGEVEAAMASIAVVVVGVVT VLVIPVFVQLIGG*" gene complement(2820090..2820785) /gene="pftB" /locus_tag="BSU_28900" /old_locus_tag="BSU28900" downshifts complement(2820112) /Source="Nicolas_upshifts" /id="D1480" /incds=0 /nref=19 /ntot=45 /MaxReadThrough="1.25312" /MaxDrop="6.13174" /score="49.3872074" /energy="-13.7" /TU="NA" /idTUdmin="U2232" /TUdmin=0 /isTUend="TRUE" downshifts complement(2820156) /Source="Nicolas_upshifts" /id="D1481" /incds=1 /nref=2 /ntot=36 /MaxReadThrough="6.79502" /MaxDrop="3.1016" /score="49.3872074" /energy="-13.7" /TU="U2232" /idTUdmin="U2232" /TUdmin="-44" /isTUend="FALSE" CDS complement(2820807..2821247) /gene="pftA" /locus_tag="BSU_28910" /old_locus_tag="BSU28910" /function="16.3: Control" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:15659658, 17452642, 26060272, 27422364, 28974613" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15659658, 17452642, 26060272, 27422364, 28974613; Product type t : transporter" /codon_start=1 /transl_table=11 /product="pyruvate uptake system subunit A" /protein_id="NP_390769.1" /db_xref="EnsemblGenomes-Gn:BSU28910" /db_xref="EnsemblGenomes-Tr:CAB14851" /db_xref="GOA:P94515" /db_xref="InterPro:IPR005538" /db_xref="InterPro:IPR023736" /db_xref="SubtiList:BG12311" /db_xref="UniProtKB/Swiss-Prot:P94515" /translation="MSAKKVYGFLTQAFIFAVIMLVSNMIAAIVPIPIPASVVGLVLL FLLLCLKVIKLEQVETLGTSLTSLIGFLFVPSGISVMNSLGVMQQYGLQIVLVILLAT IILLGATGLFSQLILSLSGKRKTEADMKTKTVQSPQNNNELVHH*" gene complement(2820807..2821247) /gene="pftA" /locus_tag="BSU_28910" /old_locus_tag="BSU28910" promotor_-10 complement(2821269..2821288) /Source="Nicolas_upshift_promotors" /id="U2232" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.434565434565435" /psig="0.982017982017982" /xcortree=1540 /SigmaFactorBS="ctgcaactcagacccgctatacggcatgttatcttgtaagcG CTTtataacagggaattcTTATTTATAATGAGGGTACCaaagagaaagaggtgaagaa a" /listShort="lrgA, lrgB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2821288) /Source="Nicolas_upshifts" /id="U2232" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.434565434565435" /psig="0.982017982017982" /xcortree=1540 /SigmaFactorBS="ctgcaactcagacccgctatacggcatgttatcttgtaagcG CTTtataacagggaattcTTATTTATAATGAGGGTACCaaagagaaagaggtgaagaa a" /listShort="lrgA, lrgB" /GFF_Attribute="listLong" promotor_-35 complement(2821304..2821307) /Source="Nicolas_upshift_promotors" /id="U2232" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.434565434565435" /psig="0.982017982017982" /xcortree=1540 /SigmaFactorBS="ctgcaactcagacccgctatacggcatgttatcttgtaagcG CTTtataacagggaattcTTATTTATAATGAGGGTACCaaagagaaagaggtgaagaa a" /listShort="lrgA, lrgB" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2821381..2822106) /gene="lytT" /locus_tag="BSU_28920" /old_locus_tag="BSU28920" /function="16.13: Shape" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:10940023, 11717295, 12034833, 12914674, 22937869, 25491472, 27127614, 27422364, 28348880" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10940023, 11717295, 12034833, 12914674, 22937869, 25491472, 27127614, 27422364, 28348880; Product type r: regulator" /codon_start=1 /transl_table=11 /product="two-component response regulator [LytS]" /protein_id="NP_390770.1" /db_xref="EnsemblGenomes-Gn:BSU28920" /db_xref="EnsemblGenomes-Tr:CAB14852" /db_xref="GOA:P94514" /db_xref="InterPro:IPR001789" /db_xref="InterPro:IPR007492" /db_xref="InterPro:IPR011006" /db_xref="SubtiList:BG11953" /db_xref="UniProtKB/Swiss-Prot:P94514" /translation="MLRVLIVDDEMLARDELAYLLKRTNDEMEINEAENIESAFDQMM DQKPDLLFLDVDLSGENGFDIAKRLKKMKHPPAIVFATAYDQYALKAFEVDALDYLTK PFDEERIQQTLKKYKKVNRDIVETEQNSHAGQHKLALSVGESIVIVDTKDIIYAGTED GHVNVKTFDHSYTVSDTLVVIEKKLPDSDFIRVHRSFVVNTEYIKEIQPWFNSTYNLI MKDGSKIPVSRTYAKELKKLLHI*" gene complement(2821381..2822106) /gene="lytT" /locus_tag="BSU_28920" /old_locus_tag="BSU28920" downshifts complement(2821410) /Source="Nicolas_upshifts" /id="D1482" /incds=0 /nref=231 /ntot=256 /MaxReadThrough="-0.0173499999999995" /MaxDrop="6.64673" /score="-8.47161605" /energy="-8.9" /TU="NA" /idTUdmin="U2232" /TUdmin="-1298" /isTUend="FALSE" CDS complement(2822084..2823865) /gene="lytS" /locus_tag="BSU_28930" /old_locus_tag="BSU28930" /function="16.3: Control" /function="16.13: Shape" /function="16.12: Sense" /experiment="publication(s) with functional evidences, PMID:10940023, 11717295, 12034833, 12914674, 22937869, 25491472, 27127614, 27422364, 28348880" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10940023, 11717295, 12034833, 12914674, 22937869, 25491472, 27127614, 27422364, 28348880; Product type rc: receptor" /codon_start=1 /transl_table=11 /product="two-component sensor histidine kinase [LytT]" /protein_id="NP_390771.1" /db_xref="EnsemblGenomes-Gn:BSU28930" /db_xref="EnsemblGenomes-Tr:CAB14853" /db_xref="GOA:P94513" /db_xref="InterPro:IPR003018" /db_xref="InterPro:IPR003594" /db_xref="InterPro:IPR005467" /db_xref="InterPro:IPR010559" /db_xref="InterPro:IPR011620" /db_xref="InterPro:IPR029016" /db_xref="InterPro:IPR036890" /db_xref="SubtiList:BG11952" /db_xref="UniProtKB/Swiss-Prot:P94513" /translation="MIHLMIMMLERVGIIVILGFILAHTKLFRQALQNQDGYKGKAIL ISIFSLFSIISNYTGIEIQRNMIVNNDWVFTIDPSGSIANTRILGVEIGGLLGGPFVG AGIGILAGLHRFSLGGSTALSCAVSSILAGVLAGLIGRYFTKRYRMPTPRIAALVGIG MESLQMIIILLMAKPFSDAWELVSMIGIPMILINGTGSFIFLSIIQAIIRKEEQARAL ETHRVLTIADQTLPFFRQGLNENSCKSVAAIIHKLTGTDAVSLTDKEKILAHVGAGMD HHIPSKSLITGLSKKVIKTGHIMKAISQEEIECTHAECPLHAAIVLPLTSNGNTIGTL KMYFKSPAGLSQVEEELAEGLAMLFSTQLELGEAELQSKLLKDAEIKALQAQVNPHFL FNAINTISALCRTDVEKTRKLLLQLSVYFRSNLQGARQLLIPLSKELNHLNAYLSLEQ ARFPGKYKIELNIDSRLEQIEIPPFVLQVLVENALRHAFPKKQDICKVTVCVLSDDAS VYMKVADNGRGIPPDVLPELGKKPFPSKEGTGTALYNLNQRLIGLFGQQAALHISSEV HKGTEVSFQVPMQQMKEGEEHAQGVNS*" gene complement(2822084..2823865) /gene="lytS" /locus_tag="BSU_28930" /old_locus_tag="BSU28930" promotor_-35 2823949..2823952 /Source="Nicolas_upshift_promotors" /id="U2234" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.513486513486514" /psig="0.999000999001" /xcortree=3039 /SigmaFactorBS="cggctgactgtttttttaaaatcgtctgaaaacatATTTcac aaggcttttatCTATTGTAAAATAAAACATGagccttttggcagaaagatttgaatct g" /listShort="ysaA" /GFF_Attribute="listLong" /label="promotor_-35" misc_feature complement(2823961..2823980) /Source="Nicolas_upshift_promotors" /id="U2233" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.632367632367632" /psig="0.999000999001" /xcortree=3026 /SigmaFactorBS="tctcctctgcttcagattcaaatctttctgccaaaaggctca tgttTTATTTTACAATAGATAAAAgccttgtgaaatatgttttcagacgattttaaaa a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(2823966) /Source="Nicolas_upshifts" /id="U2233" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.632367632367632" /psig="0.999000999001" /xcortree=3026 /SigmaFactorBS="tctcctctgcttcagattcaaatctttctgccaaaaggctca tgttTTATTTTACAATAGATAAAAgccttgtgaaatatgttttcagacgattttaaaa a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 2823967..2823986 /Source="Nicolas_upshift_promotors" /id="U2234" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.513486513486514" /psig="0.999000999001" /xcortree=3039 /SigmaFactorBS="cggctgactgtttttttaaaatcgtctgaaaacatATTTcac aaggcttttatCTATTGTAAAATAAAACATGagccttttggcagaaagatttgaatct g" /listShort="ysaA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2823974 /Source="Nicolas_upshifts" /id="U2234" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.513486513486514" /psig="0.999000999001" /xcortree=3039 /SigmaFactorBS="cggctgactgtttttttaaaatcgtctgaaaacatATTTcac aaggcttttatCTATTGTAAAATAAAACATGagccttttggcagaaagatttgaatct g" /listShort="ysaA" /GFF_Attribute="listLong" CDS 2824032..2824814 /gene="ysaA" /locus_tag="BSU_28940" /old_locus_tag="BSU28940" /EC_number="3.1.3.-" /experiment="publication(s) with functional evidences, PMID:15479782, 24123841, 25848029, 27784292" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15479782, 24123841, 25848029, 27784292; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="promiscuous phosphatase" /protein_id="NP_390772.2" /db_xref="EnsemblGenomes-Gn:BSU28940" /db_xref="EnsemblGenomes-Tr:CAB14854" /db_xref="GOA:P94512" /db_xref="InterPro:IPR006439" /db_xref="InterPro:IPR023214" /db_xref="InterPro:IPR036412" /db_xref="SubtiList:BG12310" /db_xref="UniProtKB/Swiss-Prot:P94512" /translation="MKAVFFDLDDTLLWDEKSVRTTFAETCLQAEKKYGLAPEEFEAA VREAARELYMSYETYPYTVMIGINPFEGLWSNFSEPISEGFQKLNKIVPEYRRNAWTN GLKALGIDDPAYGEYLGEFFAAERRKRPFVYDETFAVLDQLKGKYELLLLTNGDPSLQ KEKLAGVPELAPYFNEIVISGAFGKGKPDVSIFEHCLKLMNIEKDDAIMVGDNLNTDI LGASRAGIKTVWINRTDKKNETDVKPDYIISSLHDLFPILEK*" gene 2824032..2824814 /gene="ysaA" /locus_tag="BSU_28940" /old_locus_tag="BSU28940" downshifts 2824798 /Source="Nicolas_upshifts" /id="D1483" /incds=0 /nref=36 /ntot=265 /MaxReadThrough="1.0046" /MaxDrop="6.73727" /score="35.9560361" /energy="-13.8" /TU="NA" /idTUdmin="U2234" /TUdmin="-12" /isTUend="TRUE" downshifts complement(2824848) /Source="Nicolas_upshifts" /id="D1484" /incds=0 /nref=89 /ntot=246 /MaxReadThrough="1.13716" /MaxDrop="6.01766" /score="35.534455" /energy="-13.8" /TU="NA" /idTUdmin="U2235" /TUdmin="-6" /isTUend="TRUE" CDS complement(2824855..2826786) /gene="thrS" /locus_tag="BSU_28950" /old_locus_tag="BSU28950" /EC_number="6.1.1.3" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:8692931, 9826762, 10632708, 15831787, 22938038" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8692931, 9826762, 10632708, 15831787, 22938038; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="threonyl-tRNA synthetase" /protein_id="NP_390773.1" /db_xref="EnsemblGenomes-Gn:BSU28950" /db_xref="EnsemblGenomes-Tr:CAB14855" /db_xref="GOA:P18255" /db_xref="InterPro:IPR002314" /db_xref="InterPro:IPR002320" /db_xref="InterPro:IPR004095" /db_xref="InterPro:IPR004154" /db_xref="InterPro:IPR006195" /db_xref="InterPro:IPR012675" /db_xref="InterPro:IPR012676" /db_xref="InterPro:IPR012947" /db_xref="InterPro:IPR018163" /db_xref="InterPro:IPR033728" /db_xref="InterPro:IPR036621" /db_xref="SubtiList:BG10362" /db_xref="UniProtKB/Swiss-Prot:P18255" /translation="MSDMVKITFPDGAVKEFAKGTTTEDIAASISPGLKKKSLAGKLN GKEIDLRTPINEDGTVEIITEGSEEGLQIMRHSAAHLLAQAIKRIYKDVKFGVGPVIE NGFYYDVEMDEAITPEDLPKIEKEMKKIVNANLPIVRKEVSREEAKARFAEIGDDLKL ELLDAIPEGETVSIYEQGEFFDLCRGVHVPSTGKIKEFKLLSLAGAYWRGDSKNQMLQ RVYGTAFFKKADLEEHLRMLEEAKERDHRKLGKELKLFANSQKVGQGLPLWLPKGATI RRVIERYIVDKEISLGYEHVYTPVLGSKELYETSGHWDHYQEGMFPPMEMDNETLVLR PMNCPHHMMIYKQDIHSYRELPIRIAELGTMHRYEMSGALSGLQRVRGMTLNDAHIFV RPDQIKDEFIRTVRLIQDVYEDFGLSDYTFRLSYRDPEDTEKYFDDDEMWNKAQSMLK EAMDEIGHDYYEAEGEAAFYGPKLDVQVKTAIGKEETLSTVQLDFLLPERFDLTYIGE DGKQHRPVVIHRGVVSTMERFVAFLIEEHKGALPTWLAPVQFQVIPVSPAVHLDYAKK VQERLQCEGLRVEVDSRDEKIGYKIREAQMQKIPYMLVVGDQEAENGAVNVRKYGEQN SETISLDEFVKKAVAEAKK*" gene complement(2824855..2826786) /gene="thrS" /locus_tag="BSU_28950" /old_locus_tag="BSU28950" misc_RNA complement(2826830..2827077) /gene="tboT" /locus_tag="BSU_misc_RNA_48" /product="T-box riboswitch specific of threonine tRNA ligase" /experiment="publication(s) with functional evidences, PMID:9098041, 9826762, 1317842, 12165569, 12547201" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9098041, 9826762, 1317842, 12165569, 12547201; Product type n: RNA" /function="16.3: Control" gene complement(2826830..2827077) /gene="tboT" /locus_tag="BSU_misc_RNA_48" promotor_-10 complement(2826833..2826842) /Source="Nicolas_upshift_promotors" /id="U2235" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.308691308691309" /psig="0.0969030969030969" /xcortree=1774 /SigmaFactorBS="gtgtattggctttgcggaaaaaagggtggaacCacgattccg tttattcaaCCTCGTCCCTttcatagggggcggggtttttatatgcaaaaaaaggagt g" /listShort="thrS" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2826833) /Source="Nicolas_upshifts" /id="U2235" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.308691308691309" /psig="0.0969030969030969" /xcortree=1774 /SigmaFactorBS="gtgtattggctttgcggaaaaaagggtggaacCacgattccg tttattcaaCCTCGTCCCTttcatagggggcggggtttttatatgcaaaaaaaggagt g" /listShort="thrS" /GFF_Attribute="listLong" promotor_-35 complement(2826861) /Source="Nicolas_upshift_promotors" /id="U2235" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.308691308691309" /psig="0.0969030969030969" /xcortree=1774 /SigmaFactorBS="gtgtattggctttgcggaaaaaagggtggaacCacgattccg tttattcaaCCTCGTCCCTttcatagggggcggggtttttatatgcaaaaaaaggagt g" /listShort="thrS" /GFF_Attribute="listLong" /label="promotor_-35" downshifts complement(2826888) /Source="Nicolas_upshifts" /id="D1485" /incds=0 /nref=1 /ntot=16 /MaxReadThrough="6.71261" /MaxDrop="3.31801" /score="19.160794" /energy="-16.2" /TU="U2236,U2237,U2238,U2241" /idTUdmin="U2239" /TUdmin=221 /isTUend="FALSE" promotor_-10 complement(2827088..2827107) /Source="Nicolas_upshift_promotors" /id="U2236" /multdbtbs="SigA" /comp="M16" /sig="SigA" /pcomp="0.460539460539461" /psig=1 /xcortree=2576 /SigmaFactorBS="aggctgtcggtttaaaaaaaaggaaacgcgatcgTGTTGatt ttttggattgaaCAATTTATAATACATAGGAGattaagaaagacacacgtattgataa g" /listShort="NA, thrS" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2827101) /Source="Nicolas_upshifts" /id="U2236" /multdbtbs="SigA" /comp="M16" /sig="SigA" /pcomp="0.460539460539461" /psig=1 /xcortree=2576 /SigmaFactorBS="aggctgtcggtttaaaaaaaaggaaacgcgatcgTGTTGatt ttttggattgaaCAATTTATAATACATAGGAGattaagaaagacacacgtattgataa g" /listShort="NA, thrS" /GFF_Attribute="listLong" S_feature complement(2827103..2827183) /Source="Nicolas_S_feature" /locus_tag="new_2961505_2961585_c" /HighExp="S3, S4, LoTm, S5, G135, G180, LBGtran, T5.0H, G/S, G150" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigEF, SigA, SigA, SigA" /TUshortPSig="1, 1, 0.998, 0.996" /TUlongSig="NA" /TUlongPSig="NA" /label="S1090" promotor_-35 complement(2827123..2827127) /Source="Nicolas_upshift_promotors" /id="U2236" /multdbtbs="SigA" /comp="M16" /sig="SigA" /pcomp="0.460539460539461" /psig=1 /xcortree=2576 /SigmaFactorBS="aggctgtcggtttaaaaaaaaggaaacgcgatcgTGTTGatt ttttggattgaaCAATTTATAATACATAGGAGattaagaaagacacacgtattgataa g" /listShort="NA, thrS" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2827184..2828029) /gene="ytxC" /locus_tag="BSU_28960" /old_locus_tag="BSU28960" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 22882546; Product type cp : cell process" /codon_start=1 /transl_table=11 /product="sporulation protein" /protein_id="NP_390774.2" /db_xref="EnsemblGenomes-Gn:BSU28960" /db_xref="EnsemblGenomes-Tr:CAB14856" /db_xref="InterPro:IPR014199" /db_xref="SubtiList:BG10361" /db_xref="UniProtKB/Swiss-Prot:P06569" /translation="MLEIIFEDDHDAAAFLHLIQHSDDRNNIIVREGIRKIGIEKANP AFPIQRFMEPILVKFFLECKEDEHMLSLIEETYCFTDQDEQQQILQLAHSIIEGEADD LPFEPLKLSRKQSILDELQTICLEEGVFYIRSFQTFRLGSYYKQLRDITEAAIDEYKM EQEYQNFIQTLRDYVDAKQPRIKKVHIVHDGSFTLWELRYVPEREKMKYIDRRFVRDH PMYIDSHLLAPLISIAPDEVVLYTDQPEHMMARTIQNVFQERVEMLPLHAFTDAEIPV KHSEG*" gene complement(2827184..2828029) /gene="ytxC" /locus_tag="BSU_28960" /old_locus_tag="BSU28960" promotor_-10 complement(2828049..2828067) /Source="Nicolas_upshift_promotors" /id="U2237" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1000 /SigmaFactorBS="caaattaagatttgccaatgacctttaCGTCTAttttaaaaa catcccCCATATACTTGTAACAGATgccgtaaggggggacaaacatgcttgaaataat c" /listShort="ytxC, S1090, NA, thrS" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2828055) /Source="Nicolas_upshifts" /id="U2237" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1000 /SigmaFactorBS="caaattaagatttgccaatgacctttaCGTCTAttttaaaaa catcccCCATATACTTGTAACAGATgccgtaaggggggacaaacatgcttgaaataat c" /listShort="ytxC, S1090, NA, thrS" /GFF_Attribute="listLong" promotor_-35 complement(2828083..2828088) /Source="Nicolas_upshift_promotors" /id="U2237" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1000 /SigmaFactorBS="caaattaagatttgccaatgacctttaCGTCTAttttaaaaa catcccCCATATACTTGTAACAGATgccgtaaggggggacaaacatgcttgaaataat c" /listShort="ytxC, S1090, NA, thrS" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2828108..2828749) /gene="ytxB" /locus_tag="BSU_28970" /old_locus_tag="BSU28970" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406, 25728272, 27190159; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative osomosensing transporter" /protein_id="NP_390775.1" /db_xref="EnsemblGenomes-Gn:BSU28970" /db_xref="EnsemblGenomes-Tr:CAB14857" /db_xref="GOA:P06568" /db_xref="InterPro:IPR015414" /db_xref="InterPro:IPR032816" /db_xref="SubtiList:BG10360" /db_xref="UniProtKB/Swiss-Prot:P06568" /translation="MKRKTAVKWLAVLAGAGLLYWGNKTYLNVSPKEIRVWVLSFGVF APLMFIGISIVRPLVLFPVSVISIAGGLAFGPLLGTLYTLFGSMCASAVSFFAAGLFS AKKNGHYERLEAIQKQMEDNGFFYIFLLRILPINFDFVSYAAGLSNVKALPYFAATAV GIIPGTIALNVLGASFLAGNLPAFFMVLALYIVFISLPFIFRKKMQNLFQESN*" gene complement(2828108..2828749) /gene="ytxB" /locus_tag="BSU_28970" /old_locus_tag="BSU28970" CDS complement(2828783..2829718) /gene="dnaI" /locus_tag="BSU_28980" /old_locus_tag="BSU28980" /function="16.9: Replicate" /experiment="publication(s) with functional evidences, PMID:12682299, 17003052, 17289076, 19255093, 19968790" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12682299, 17003052, 17289076, 19255093, 19968790; Product type f: factor" /codon_start=1 /transl_table=11 /product="helicase loader" /protein_id="NP_390776.1" /db_xref="EnsemblGenomes-Gn:BSU28980" /db_xref="EnsemblGenomes-Tr:CAB14858" /db_xref="GOA:P06567" /db_xref="InterPro:IPR002611" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR009928" /db_xref="InterPro:IPR027417" /db_xref="PDB:2K7R" /db_xref="PDB:4M4W" /db_xref="SubtiList:BG10359" /db_xref="UniProtKB/Swiss-Prot:P06567" /translation="MEPIGRSLQGVTGRPDFQKRLEQMKEKVMKDQDVQAFLKENEEV IDQKMIEKSLNKLYEYIEQSKNCSYCSEDENCNNLLEGYHPKLVVNGRSIDIEYYECP VKRKLDQQKKQQSLMKSMYIQQDLLGATFQQVDISDPSRLAMFQHVTDFLKSYNETGK GKGLYLYGKFGVGKTFMLAAIANELAEKEYSSMIVYVPEFVRELKNSLQDQTLEEKLN MVKTTPVLMLDDIGAESMTSWVRDEVIGTVLQHRMSQQLPTFFSSNFSPDELKHHFTY SQRGEKEEVKAARLMERILYLAAPIRLDGENRRHP*" gene complement(2828783..2829718) /gene="dnaI" /locus_tag="BSU_28980" /old_locus_tag="BSU28980" CDS complement(2829746..2831164) /gene="dnaB" /locus_tag="BSU_28990" /old_locus_tag="BSU28990" /function="16.9: Replicate" /experiment="publication(s) with functional evidences, PMID:12682299, 15186423, 16002087, 17289076, 20071750, 21097613, 23525462" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12682299, 15186423, 16002087, 17289076, 20071750, 21097613, 23525462; Product type f: factor" /codon_start=1 /transl_table=11 /product="helicase loading protein; replication initiationmembrane attachment protein" /protein_id="NP_390777.1" /db_xref="EnsemblGenomes-Gn:BSU28990" /db_xref="EnsemblGenomes-Tr:CAB14859" /db_xref="GOA:P07908" /db_xref="InterPro:IPR006343" /db_xref="InterPro:IPR034829" /db_xref="SubtiList:BG10358" /db_xref="UniProtKB/Swiss-Prot:P07908" /translation="MADYWKDVLPVDPYVVKSRSMLQDIDRQIITQLYQPLIGPVAFS LYMTLWGELEQNRLWGGESTHRQLMGMTQSNLKTIHQEQGKLEGIGLLKVYMKESERQ ERLFIYELLPPLRPNEFFEDGMLNVFLYNRVGKTKYQQLKQFFTHPAISEDAKDITRP FNHAFESLQPSEWKLTSDMEETVRLAEGSEYTSVGQSPSYTITEDVFDFDLFLAGLSE TMIPRKAMTQQVRDTIKKLSYLYGIDPLQMQNVVMSAIDERDVITTEALRKAASDWYQ IERNGQLPDLVEKTQPVHLREGEQPAEEDSLDGKLIALLEAISPKKLLQDIADGTEPS KADLKIIEEIMFEQKLEPGVTNVLIYYVMLKTDMKLSKNYIQKIASHWARKKVKTVRE AMKLAIEENRQYLEWAEGKTKSSKRNQKVIREEKLPDWMTEKETASDSESGQQKLHPQ DLEEQKKKMMEEMQKLKKYSAY*" gene complement(2829746..2831164) /gene="dnaB" /locus_tag="BSU_28990" /old_locus_tag="BSU28990" promotor_-10 complement(2831193..2831212) /Source="Nicolas_upshift_promotors" /id="U2238" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.865134865134865" /psig=1 /xcortree=2245 /SigmaFactorBS="ttctagctcttttctcatgtgcaaaattggcATTTgatagat ataagaaACGGTGTAAAATGAAAGGTAgaaacaaattcggaaggtttgagaatgtatg g" /listShort="dnaB, dnaI, ytxB, ytxC, S1090, NA, thrS" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2831201) /Source="Nicolas_upshifts" /id="U2238" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.865134865134865" /psig=1 /xcortree=2245 /SigmaFactorBS="ttctagctcttttctcatgtgcaaaattggcATTTgatagat ataagaaACGGTGTAAAATGAAAGGTAgaaacaaattcggaaggtttgagaatgtatg g" /listShort="dnaB, dnaI, ytxB, ytxC, S1090, NA, thrS" /GFF_Attribute="listLong" promotor_-35 complement(2831227..2831230) /Source="Nicolas_upshift_promotors" /id="U2238" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.865134865134865" /psig=1 /xcortree=2245 /SigmaFactorBS="ttctagctcttttctcatgtgcaaaattggcATTTgatagat ataagaaACGGTGTAAAATGAAAGGTAgaaacaaattcggaaggtttgagaatgtatg g" /listShort="dnaB, dnaI, ytxB, ytxC, S1090, NA, thrS" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2831279..2831737) /gene="nrdR" /locus_tag="BSU_29000" /old_locus_tag="BSU29000" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:16950922, 27920297, 28624879" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16950922, 27920297, 28624879; Product type r: regulator" /codon_start=1 /transl_table=11 /product="negative regulator of transcription of ribonucleotide reductase nrd genes and operons" /protein_id="NP_390778.1" /db_xref="EnsemblGenomes-Gn:BSU29000" /db_xref="EnsemblGenomes-Tr:CAB14860" /db_xref="GOA:Q45549" /db_xref="InterPro:IPR003796" /db_xref="InterPro:IPR005144" /db_xref="SubtiList:BG13833" /db_xref="UniProtKB/Swiss-Prot:Q45549" /translation="MKCPSCQHNGTRVLDSRPVDDGKSIRRRRECESCHYRFTTFEKV EETPLIVVKKEGVREEFSREKMLRGLIKACEKRPVSLKTLEDMCFDIEKELRNQGCSE VKSELVGEMVMDRLAKIDEVAYVRFASVYRQFKDINVFIDELKDLIKKER*" gene complement(2831279..2831737) /gene="nrdR" /locus_tag="BSU_29000" /old_locus_tag="BSU29000" downshifts complement(2831298) /Source="Nicolas_upshifts" /id="D1486" /incds=0 /nref=14 /ntot=175 /MaxReadThrough="4.1553" /MaxDrop="3.90408" /score="12.4797073" /energy="-21.2" /TU="U2239,U2241" /idTUdmin="U2243" /TUdmin="-9" /isTUend="TRUE" S_feature complement(2831738..2831885) /Source="Nicolas_S_feature" /locus_tag="new_2966140_2966287_c" /HighExp="dia5, dia15, Lbstat, Diami, Heat, M9-stat, M0t90, M40t90, LBGtran, C90" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA, SigGF, SigA" /TUshortPSig="0.998, 0.996, 0.654, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S1091" promotor_-10 complement(2831876..2831895) /Source="Nicolas_upshift_promotors" /id="U2239" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.917082917082917" /psig="0.998001998001998" /xcortree=1862 /SigmaFactorBS="cttttatttttataaagaaacgagagtgtcagCTTTttcttt tttcatttTTTTTGTAAAATAAGAAGGAgattttcacaaaccacctaatgctatagaa a" /listShort="S1091, nrdR, dnaB, dnaI, ytxB, ytxC, S1090" /listLong="NA, thrS" /label="promotor_-10" upshifts complement(2831885) /Source="Nicolas_upshifts" /id="U2239" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.917082917082917" /psig="0.998001998001998" /xcortree=1862 /SigmaFactorBS="cttttatttttataaagaaacgagagtgtcagCTTTttcttt tttcatttTTTTTGTAAAATAAGAAGGAgattttcacaaaccacctaatgctatagaa a" /listShort="S1091, nrdR, dnaB, dnaI, ytxB, ytxC, S1090" /listLong="NA, thrS" S_feature complement(2831887..2831965) /Source="Nicolas_S_feature" /locus_tag="new_2966289_2966367_c" /HighExp="Lbstat, M40t90, Heat, M9-stat, M0t90, G180, S8, S5, T1.30H, G135" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigGF, SigA" /TUshortPSig="0.996, 0.654, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S1092" promotor_-35 complement(2831910..2831913) /Source="Nicolas_upshift_promotors" /id="U2239" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.917082917082917" /psig="0.998001998001998" /xcortree=1862 /SigmaFactorBS="cttttatttttataaagaaacgagagtgtcagCTTTttcttt tttcatttTTTTTGTAAAATAAGAAGGAgattttcacaaaccacctaatgctatagaa a" /listShort="S1091, nrdR, dnaB, dnaI, ytxB, ytxC, S1090" /listLong="NA, thrS" /label="promotor_-35" downshifts complement(2832010) /Source="Nicolas_upshifts" /id="D1487" /incds=0 /nref=204 /ntot=262 /MaxReadThrough="5.70146" /MaxDrop="5.85416" /score="12.4797073" /energy="-21.2" /TU="U2241,U2242,U2243" /idTUdmin="U2242" /TUdmin="-237" /isTUend="FALSE" CDS complement(2832011..2832391) /gene="speD" /locus_tag="BSU_29010" /old_locus_tag="BSU29010" /EC_number="4.1.1.50" /function="16.2: Construct biomass (Anabolism)" /function="16.3: Control" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:9723923, 10844697, 28546427" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9723923, 10844697, 28546427; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="S-adenosylmethionine decarboxylase" /protein_id="NP_390779.2" /db_xref="EnsemblGenomes-Gn:BSU29010" /db_xref="EnsemblGenomes-Tr:CAB14861" /db_xref="GOA:O34426" /db_xref="InterPro:IPR003826" /db_xref="InterPro:IPR016067" /db_xref="InterPro:IPR017716" /db_xref="SubtiList:BG13832" /db_xref="UniProtKB/Swiss-Prot:O34426" /translation="METMGRHVISELWGCDFDKLNDMDFIEKTFVNAALKSGAEVREV AFHKFAPQGVSGVVIISESHLTIHSFPEHGYASIDVYTCGDLDPNVAADYIAEALHAD TRENIEIPRGMGPVQIKQAQAKVL*" gene complement(2832011..2832391) /gene="speD" /locus_tag="BSU_29010" /old_locus_tag="BSU29010" S_feature complement(2832392..2832546) /Source="Nicolas_S_feature" /locus_tag="new_2966794_2966948_c" /HighExp="Lbstat, M40t90, M9-stat, T2.0H, T3.0H, M0t90, T3.30H, Sw, T1.30H, T2.30H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigGF, SigA" /TUshortPSig="0.996, 0.654, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S1093" promotor_-10 complement(2832526..2832545) /Source="Nicolas_upshift_promotors" /id="U2241" /multdbtbs="SigA" /comp="M17" /sig="SigA" /pcomp="0.613386613386613" /psig="0.996003996003996" /xcortree=337 /SigmaFactorBS="aagaaaaaacccttaacagcatatttctgaaaaaacgcacCT TGCAAattagacttaaacaCAGTATACTATTTTTCGTGAacttcttgcttgagactgt t" /listShort="S1093, speD, S1092, S1091, nrdR, dnaB, dnaI, ytxB, ytxC, S1090, NA, thrS" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2832533 /Source="Nicolas_upshifts" /id="U2240" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.300699300699301" /psig="0.822177822177822" /xcortree=292 /SigmaFactorBS="ccggagaggtcctaaccctttaagtaattccgaaacagtctc aagcaagaagttcacgaaaAATAGTATACTGTGTTTAAGtctaatttgcaaggtgcgt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" misc_feature 2832534..2832553 /Source="Nicolas_upshift_promotors" /id="U2240" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.300699300699301" /psig="0.822177822177822" /xcortree=292 /SigmaFactorBS="ccggagaggtcctaaccctttaagtaattccgaaacagtctc aagcaagaagttcacgaaaAATAGTATACTGTGTTTAAGtctaatttgcaaggtgcgt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(2832546) /Source="Nicolas_upshifts" /id="U2241" /multdbtbs="SigA" /comp="M17" /sig="SigA" /pcomp="0.613386613386613" /psig="0.996003996003996" /xcortree=337 /SigmaFactorBS="aagaaaaaacccttaacagcatatttctgaaaaaacgcacCT TGCAAattagacttaaacaCAGTATACTATTTTTCGTGAacttcttgcttgagactgt t" /listShort="S1093, speD, S1092, S1091, nrdR, dnaB, dnaI, ytxB, ytxC, S1090, NA, thrS" /GFF_Attribute="listLong" promotor_-35 complement(2832560..2832566) /Source="Nicolas_upshift_promotors" /id="U2241" /multdbtbs="SigA" /comp="M17" /sig="SigA" /pcomp="0.613386613386613" /psig="0.996003996003996" /xcortree=337 /SigmaFactorBS="aagaaaaaacccttaacagcatatttctgaaaaaacgcacCT TGCAAattagacttaaacaCAGTATACTATTTTTCGTGAacttcttgcttgagactgt t" /listShort="S1093, speD, S1092, S1091, nrdR, dnaB, dnaI, ytxB, ytxC, S1090, NA, thrS" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(2832624..2832635) /Source="Nicolas_upshift_promotors" /id="U2242" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.654345654345654" /psig="0.654345654345654" /xcortree=339 /SigmaFactorBS="gcagagttgttgatctaatccgccatgtagcggcaCGAATGA aacatccgtctgctGTATAAAATAAGgtcatggacacattttaaagaaaaaaccctta a" /listShort="S1093, speD, S1092, S1091" /GFF_Attribute="listLong" /label="promotor_-10" CDS complement(2832630..2833652) /gene="gapB" /locus_tag="BSU_29020" /old_locus_tag="BSU29020" /EC_number="1.2.1.59" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:10799476, 10844697, 15720552, 22720735, 26735940, 27449348, 28760849" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10799476, 10844697, 15720552, 22720735, 26735940, 27449348, 28760849; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="glyceraldehyde-3-phosphate dehydrogenase (NADP-dependent, gluconeogenesis)" /protein_id="NP_390780.1" /db_xref="EnsemblGenomes-Gn:BSU29020" /db_xref="EnsemblGenomes-Tr:CAB14862" /db_xref="GOA:O34425" /db_xref="InterPro:IPR006424" /db_xref="InterPro:IPR020828" /db_xref="InterPro:IPR020829" /db_xref="InterPro:IPR020830" /db_xref="InterPro:IPR020831" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG12592" /db_xref="UniProtKB/Swiss-Prot:O34425" /translation="MKVKVAINGFGRIGRMVFRKAMLDDQIQVVAINASYSAETLAHL IKYDTIHGRYDKEVVAGEDSLIVNGKKVLLLNSRDPKQLPWREYDIDIVVEATGKFNA KDKAMGHIEAGAKKVILTAPGKNEDVTIVMGVNEDQFDAERHVIISNASCTTNCLAPV VKVLDEEFGIESGLMTTVHAYTNDQKNIDNPHKDLRRARACGESIIPTTTGAAKALSL VLPHLKGKLHGLALRVPVPNVSLVDLVVDLKTDVTAEEVNEAFKRAAKTSMYGVLDYS DEPLVSTDYNTNPHSAVIDGLTTMVMEDRKVKVLAWYDNEWGYSCRVVDLIRHVAARM KHPSAV*" gene complement(2832630..2833652) /gene="gapB" /locus_tag="BSU_29020" /old_locus_tag="BSU29020" upshifts complement(2832631) /Source="Nicolas_upshifts" /id="U2242" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.654345654345654" /psig="0.654345654345654" /xcortree=339 /SigmaFactorBS="gcagagttgttgatctaatccgccatgtagcggcaCGAATGA aacatccgtctgctGTATAAAATAAGgtcatggacacattttaaagaaaaaaccctta a" /listShort="S1093, speD, S1092, S1091" /GFF_Attribute="listLong" promotor_-35 complement(2832650..2832656) /Source="Nicolas_upshift_promotors" /id="U2242" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.654345654345654" /psig="0.654345654345654" /xcortree=339 /SigmaFactorBS="gcagagttgttgatctaatccgccatgtagcggcaCGAATGA aacatccgtctgctGTATAAAATAAGgtcatggacacattttaaagaaaaaaccctta a" /listShort="S1093, speD, S1092, S1091" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(2833696..2833715) /Source="Nicolas_upshift_promotors" /id="U2243" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.633366633366633" /psig=1 /xcortree=347 /SigmaFactorBS="acataagatgcatcataaattagcgttataatcgttgatttt tatcaatatgTACTGGCGaatttgttttaaTGTGTTATACTAATTTTAGAtagtaaca a" /listShort="gapB, S1093, speD, S1092, S1091, nrdR" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2833727) /Source="Nicolas_upshifts" /id="U2243" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.633366633366633" /psig=1 /xcortree=347 /SigmaFactorBS="acataagatgcatcataaattagcgttataatcgttgatttt tatcaatatgTACTGGCGaatttgttttaaTGTGTTATACTAATTTTAGAtagtaaca a" /listShort="gapB, S1093, speD, S1092, S1091, nrdR" /GFF_Attribute="listLong" promotor_-35 complement(2833728..2833735) /Source="Nicolas_upshift_promotors" /id="U2243" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.633366633366633" /psig=1 /xcortree=347 /SigmaFactorBS="acataagatgcatcataaattagcgttataatcgttgatttt tatcaatatgTACTGGCGaatttgttttaaTGTGTTATACTAATTTTAGAtagtaaca a" /listShort="gapB, S1093, speD, S1092, S1091, nrdR" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2833858..2834238) /gene="ytcD" /locus_tag="BSU_29030" /old_locus_tag="BSU29030" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 23504016; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative transcriptional regulator (HxlR family)" /protein_id="NP_390781.1" /db_xref="EnsemblGenomes-Gn:BSU29030" /db_xref="EnsemblGenomes-Tr:CAB14863" /db_xref="GOA:O34533" /db_xref="InterPro:IPR002577" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="PDB:2HZT" /db_xref="SubtiList:BG13831" /db_xref="UniProtKB/Swiss-Prot:O34533" /translation="MEKKKYNISVEATLEVIGGKWKCVILCHLTHGKKRTSELKRLMP NITQKMLTQQLRELEADGVINRIVYNQVPPKVEYELSEYGRSLEGILDMLCAWGANHI NRVYGDTFSVLEESVLNDKLKQES*" gene complement(2833858..2834238) /gene="ytcD" /locus_tag="BSU_29030" /old_locus_tag="BSU29030" downshifts complement(2833882) /Source="Nicolas_upshifts" /id="D1488" /incds=0 /nref=17 /ntot=164 /MaxReadThrough="1.55675" /MaxDrop="3.64816" /score="18.9828659" /energy="-15.3" /TU="NA" /idTUdmin="U2245" /TUdmin=3 /isTUend="TRUE" S_feature complement(2834239..2834369) /Source="Nicolas_S_feature" /locus_tag="new_2968641_2968771_c" /HighExp="dia15, Diami, dia5, LBGstat, G180, Etha, S5, LBGtran, H2O2, LBGexp" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.972" /TUlongSig="NA" /TUlongPSig="NA" /label="S1094" promotor_-35 2834294..2834298 /Source="Nicolas_upshift_promotors" /id="U2244" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.87012987012987" /psig="0.972027972027972" /xcortree=2468 /SigmaFactorBS="acaggcaccaaaaagtgactatagcacttcaaagtacgtACT TTtatttcttaacgataTGTTTCATAATCACATTTGCcggctgatttgaatctgctct t" /listShort="S1095, ytbD, ytbE" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2834314..2834333 /Source="Nicolas_upshift_promotors" /id="U2244" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.87012987012987" /psig="0.972027972027972" /xcortree=2468 /SigmaFactorBS="acaggcaccaaaaagtgactatagcacttcaaagtacgtACT TTtatttcttaacgataTGTTTCATAATCACATTTGCcggctgatttgaatctgctct t" /listShort="S1095, ytbD, ytbE" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 2834315..2834421 /Source="Nicolas_S_feature" /locus_tag="new_2968717_2968823" /HighExp="Diami, G180, G135, LBGstat, G150, LBGexp, Paraq, Oxctl, dia5, S8" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.972" /TUlongSig="NA" /TUlongPSig="NA" /label="S1095" upshifts 2834315 /Source="Nicolas_upshifts" /id="U2244" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.87012987012987" /psig="0.972027972027972" /xcortree=2468 /SigmaFactorBS="acaggcaccaaaaagtgactatagcacttcaaagtacgtACT TTtatttcttaacgataTGTTTCATAATCACATTTGCcggctgatttgaatctgctct t" /listShort="S1095, ytbD, ytbE" /GFF_Attribute="listLong" promotor_-10 complement(2834359..2834378) /Source="Nicolas_upshift_promotors" /id="U2245" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.935064935064935" /psig="0.972027972027972" /xcortree=1937 /SigmaFactorBS="gaagtcatgatgttcctcctttgtaagatGTGTTGTAtgatt gaaattctgCCGAGTAAGCTATATAAATAaaaaagagcagattcaaatcagccggcaa a" /listShort="S1094, ytcD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2834369) /Source="Nicolas_upshifts" /id="U2245" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.935064935064935" /psig="0.972027972027972" /xcortree=1937 /SigmaFactorBS="gaagtcatgatgttcctcctttgtaagatGTGTTGTAtgatt gaaattctgCCGAGTAAGCTATATAAATAaaaaagagcagattcaaatcagccggcaa a" /listShort="S1094, ytcD" /GFF_Attribute="listLong" promotor_-35 complement(2834393..2834400) /Source="Nicolas_upshift_promotors" /id="U2245" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.935064935064935" /psig="0.972027972027972" /xcortree=1937 /SigmaFactorBS="gaagtcatgatgttcctcctttgtaagatGTGTTGTAtgatt gaaattctgCCGAGTAAGCTATATAAATAaaaaagagcagattcaaatcagccggcaa a" /listShort="S1094, ytcD" /GFF_Attribute="listLong" /label="promotor_-35" CDS 2834422..2835612 /gene="ytbD" /locus_tag="BSU_29040" /old_locus_tag="BSU29040" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406, 23504016; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative transporter" /protein_id="NP_390782.1" /db_xref="EnsemblGenomes-Gn:BSU29040" /db_xref="EnsemblGenomes-Tr:CAB14864" /db_xref="GOA:O34367" /db_xref="InterPro:IPR011701" /db_xref="InterPro:IPR020846" /db_xref="InterPro:IPR036259" /db_xref="SubtiList:BG13825" /db_xref="UniProtKB/Swiss-Prot:O34367" /translation="MTSANKSNIPALLALAVSAFAIGTTEFISVGLLPLIADDLDIPV TTAGLTVSLYALGVTFGAPILTSLTSSMSRKTLLLWIMFIFIAGNTMAATASSIGILL AARVISAFSHGVFMSIGSTIAADIVPEDKRASAISIMFTGLTVATVTGVPFGTFIGQQ FGWRFAFMVIIAVGIIAFITNGILVPSKLRKGTKTTMRDQLKLVTNSRLLLLFVITAL GYGGTFVVFTYLSPLLQEVTGFKAGTVAVILLGYGIAIAIGNMIGGKLSNRNPIAALF YMFIVQAIVLFVLTFTAPYQAAGLITILCMGLLAFMNVPGLQVYVVMLAERFVPSAVD VASAMNIAAFNAGIALGSYLGGVITDSIGLIHTAWIGGLMVVGAVILTGWSRLMEKRD RQEA*" gene 2834422..2835612 /gene="ytbD" /locus_tag="BSU_29040" /old_locus_tag="BSU29040" promotor_-10 complement(2835244..2835262) /Source="Nicolas_upshift_promotors" /id="U2246" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.957042957042957" /psig="0.957042957042957" /xcortree=1038 /SigmaFactorBS="agccctgctgcttgatacggggctgtaaatgtcagtaCGAAT AgaacgattgcctgtaCGATAAACATATAGAATAAagcggcaatcggatttcggtttg a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2835260) /Source="Nicolas_upshifts" /id="U2246" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.957042957042957" /psig="0.957042957042957" /xcortree=1038 /SigmaFactorBS="agccctgctgcttgatacggggctgtaaatgtcagtaCGAAT AgaacgattgcctgtaCGATAAACATATAGAATAAagcggcaatcggatttcggtttg a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(2835278..2835283) /Source="Nicolas_upshift_promotors" /id="U2246" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.957042957042957" /psig="0.957042957042957" /xcortree=1038 /SigmaFactorBS="agccctgctgcttgatacggggctgtaaatgtcagtaCGAAT AgaacgattgcctgtaCGATAAACATATAGAATAAagcggcaatcggatttcggtttg a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" CDS 2835636..2836478 /gene="ytbE" /locus_tag="BSU_29050" /old_locus_tag="BSU29050" /EC_number="1.1.1.-" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:19585557, 20981419, 28032445, 28130301" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 19585557, 20981419, 28032445, 28130301; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="promiscuous aldo/keto reductase" /protein_id="NP_390783.1" /db_xref="EnsemblGenomes-Gn:BSU29050" /db_xref="EnsemblGenomes-Tr:CAB14865" /db_xref="GOA:O34678" /db_xref="InterPro:IPR018170" /db_xref="InterPro:IPR020471" /db_xref="InterPro:IPR023210" /db_xref="InterPro:IPR036812" /db_xref="PDB:3B3D" /db_xref="SubtiList:BG13826" /db_xref="UniProtKB/Swiss-Prot:O34678" /translation="MTTHLQAKATLHNGVEMPWFGLGVFQVEEGSELVNAVKTAIVHG YRSIDTAAIYGNEAGVGEGIREGIEEAGISREDLFITSKVWNADLGYEETLAAFETSL SKLGLDYLDLYLIHWPVEGKYKEAWRALETLYKEGRIKAIGVSNFQIHHLEDLMTAAE IKPMINQVEFHPRLTQKELIRYCQNQGIQMEAWSPLMQGQLLDHPVLADIAQTYNKSV AQIILRWDLQHGIITIPKSTKEHRIKENASVFDFELTQDDMNRIDALNENLRVGPDPD NFDF*" gene 2835636..2836478 /gene="ytbE" /locus_tag="BSU_29050" /old_locus_tag="BSU29050" promotor_-35 2836251..2836256 /Source="Nicolas_upshift_promotors" /id="U2247" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.993006993006993" /psig="0.993006993006993" /xcortree=1181 /SigmaFactorBS="ggtcacctttaatgcagggacagctgctggatcaccctGTAT TGgctgacatcgctcaaACATATAATAAATCTGTCGcacaaattattttgcgctggga t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2836272..2836290 /Source="Nicolas_upshift_promotors" /id="U2247" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.993006993006993" /psig="0.993006993006993" /xcortree=1181 /SigmaFactorBS="ggtcacctttaatgcagggacagctgctggatcaccctGTAT TGgctgacatcgctcaaACATATAATAAATCTGTCGcacaaattattttgcgctggga t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2836273 /Source="Nicolas_upshifts" /id="U2247" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.993006993006993" /psig="0.993006993006993" /xcortree=1181 /SigmaFactorBS="ggtcacctttaatgcagggacagctgctggatcaccctGTAT TGgctgacatcgctcaaACATATAATAAATCTGTCGcacaaattattttgcgctggga t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" downshifts 2836471 /Source="Nicolas_upshifts" /id="D1489" /incds=0 /nref=13 /ntot=124 /MaxReadThrough="1.16017" /MaxDrop="5.72508" /score="24.0721062" /energy="-11.4" /TU="NA" /idTUdmin="U2244" /TUdmin=0 /isTUend="TRUE" downshifts complement(2836511) /Source="Nicolas_upshifts" /id="D1490" /incds=0 /nref=168 /ntot=263 /MaxReadThrough="3.38494" /MaxDrop="6.57333" /score="13.4291259" /energy="-11.4" /TU="NA" /idTUdmin="U2248" /TUdmin="-8" /isTUend="TRUE" CDS complement(2836520..2837113) /gene="coaE" /locus_tag="BSU_29060" /old_locus_tag="BSU29060" /EC_number="2.7.1.24" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 10939241, 11886213, 12538896, 12682299, 15044829, 15526298, 17603993; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="dephosphocoenzyme A kinase" /protein_id="NP_390784.1" /db_xref="EnsemblGenomes-Gn:BSU29060" /db_xref="EnsemblGenomes-Tr:CAB14866" /db_xref="GOA:O34932" /db_xref="InterPro:IPR001977" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG13824" /db_xref="UniProtKB/Swiss-Prot:O34932" /translation="MTLVIGLTGGIASGKSTVANMLIEKGITVIDADIIAKQAVEKGM PAYRQIIDEFGEDILLSNGDIDRKKLGALVFTNEQKRLALNAIVHPAVRQEMLNRRDE AVANREAFVVLDIPLLFESKLESLVDKIIVVSVTKELQLERLMKRNQLTEEEAVSRIR SQMPLEEKTARADQVIDNSGTLEETKRQLDEIMNSWA*" gene complement(2836520..2837113) /gene="coaE" /locus_tag="BSU_29060" /old_locus_tag="BSU29060" CDS complement(2837129..2837761) /gene="spcF" /locus_tag="BSU_29070" /old_locus_tag="BSU29070" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:15849754, 16850406, 23396918" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15849754, 16850406, 23396918; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="membrane calmodulin-like protein essential for stage III sporulation" /protein_id="NP_390785.2" /db_xref="EnsemblGenomes-Gn:BSU29070" /db_xref="EnsemblGenomes-Tr:CAB14867" /db_xref="GOA:C0SP79" /db_xref="InterPro:IPR003810" /db_xref="InterPro:IPR014205" /db_xref="SubtiList:BG13823" /db_xref="UniProtKB/Swiss-Prot:C0SP79" /translation="MQMVSILLLALAVSLDSFSVGFTYGLRKMKIPFKAILVIACCSG AVMFISMLIGSFLTKFFPVYVTEKLGGLILVGIGAWVLYQFFKPAKDKEYLLHEKTLL NLEVRSLGIVIHILRKPMSADIDKSGVINGIEAVLLGFALSIDAFGAGIGAAILGFSP IVMSIAVAIMSSLFVSIGINAGHFLSKWKWIDKMAFLPGLLLITIGLWKL*" gene complement(2837129..2837761) /gene="spcF" /locus_tag="BSU_29070" /old_locus_tag="BSU29070" S_feature complement(2837762..2837926) /Source="Nicolas_S_feature" /locus_tag="new_2972164_2972328_c" /HighExp="LPhT, dia15, Sw, LBGtran, LBGstat, H2O2, Diami, G135, Lbstat, C90" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="1, 0.995" /TUlongSig="NA" /TUlongPSig="NA" /label="S1096" CDS complement(2837927..2838757) /gene="mutM" /locus_tag="BSU_29080" /old_locus_tag="BSU29080" /EC_number="3.2.2.23" /function="16.6: Maintain" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 15109717, 25825434, 28517932; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="formamidopyrimidine-DNA glycosylase; 5-hydroxymethyl-uracil DNA-glycosylase" /protein_id="NP_390786.2" /db_xref="EnsemblGenomes-Gn:BSU29080" /db_xref="EnsemblGenomes-Tr:CAB14868" /db_xref="GOA:O34403" /db_xref="InterPro:IPR000214" /db_xref="InterPro:IPR010663" /db_xref="InterPro:IPR010979" /db_xref="InterPro:IPR012319" /db_xref="InterPro:IPR015886" /db_xref="InterPro:IPR015887" /db_xref="InterPro:IPR020629" /db_xref="InterPro:IPR035937" /db_xref="SubtiList:BG12628" /db_xref="UniProtKB/Swiss-Prot:O34403" /translation="MPELPEVETVRRTLTGLVKGKTIKSVEIRWPNIIKRPAEPEEFA RKLAGETIQSIGRRGKFLLFHLDHYVMVSHLRMEGKYGLHQAEEPDDKHVHVIFTMTD GTQLRYRDVRKFGTMHLFKPGEEAGELPLSQLGPEPDAEEFTSAYLKDRLAKTNRAVK TALLDQKTVVGLGNIYVDEALFRAGVHPETKANQLSDKTIKTLHAEIKNTLQEAIDAG GSTVRSYINSQGEIGMFQLQHFVYGKKDEPCKNCGTMISKIVVGGRGTHFCAKCQTKK *" gene complement(2837927..2838757) /gene="mutM" /locus_tag="BSU_29080" /old_locus_tag="BSU29080" CDS complement(2838780..2841422) /gene="polA" /locus_tag="BSU_29090" /old_locus_tag="BSU29090" /EC_number="2.7.7.7" /function="16.9: Replicate" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:3125407, 6777244, 9231429, 12081953, 17905985, 27399782" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 3125407, 6777244, 9231429, 12081953, 17905985, 27399782; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="DNA polymerase I" /protein_id="NP_390787.1" /db_xref="EnsemblGenomes-Gn:BSU29090" /db_xref="EnsemblGenomes-Tr:CAB14869" /db_xref="GOA:O34996" /db_xref="InterPro:IPR001098" /db_xref="InterPro:IPR002298" /db_xref="InterPro:IPR002421" /db_xref="InterPro:IPR002562" /db_xref="InterPro:IPR008918" /db_xref="InterPro:IPR012337" /db_xref="InterPro:IPR018320" /db_xref="InterPro:IPR019760" /db_xref="InterPro:IPR020045" /db_xref="InterPro:IPR020046" /db_xref="InterPro:IPR029060" /db_xref="InterPro:IPR036279" /db_xref="InterPro:IPR036397" /db_xref="SubtiList:BG12656" /db_xref="UniProtKB/Swiss-Prot:O34996" /translation="MTERKKLVLVDGNSLAYRAFFALPLLSNDKGVHTNAVYGFAMIL MKMLEDEKPTHMLVAFDAGKTTFRHGTFKEYKGGRQKTPPELSEQMPFIRELLDAYQI SRYELEQYEADDIIGTLAKSAEKDGFEVKVFSGDKDLTQLATDKTTVAITRKGITDVE FYTPEHVKEKYGLTPEQIIDMKGLMGDSSDNIPGVPGVGEKTAIKLLKQFDSVEKLLE SIDEVSGKKLKEKLEEFKDQALMSKELATIMTDAPIEVSVSGLEYQGFNREQVIAIFK DLGFNTLLERLGEDSAEAEQDQSLEDINVKTVTDVTSDILVSPSAFVVEQIGDNYHEE PILGFSIVNETGAYFIPKDIAVESEVFKEWVENDEQKKWVFDSKRAVVALRWQGIELK GAEFDTLLAAYIINPGNSYDDVASVAKDYGLHIVSSDESVYGKGAKRAVPSEDVLSEH LGRKALAIQSLREKLVQELENNDQLELFEELEMPLALILGEMESTGVKVDVDRLKRMG EELGAKLKEYEEKIHEIAGEPFNINSPKQLGVILFEKIGLPVVKKTKTGYSTSADVLE KLADKHDIVDYILQYRQIGKLQSTYIEGLLKVTRPDSHKVHTRFNQALTQTGRLSSTD PNLQNIPIRLEEGRKIRQAFVPSEKDWLIFAADYSQIELRVLAHISKDENLIEAFTND MDIHTKTAMDVFHVAKDEVTSAMRRQAKAVNFGIVYGISDYGLSQNLGITRKEAGAFI DRYLESFQGVKAYMEDSVQEAKQKGYVTTLMHRRRYIPELTSRNFNIRSFAERTAMNT PIQGSAADIIKKAMIDMAAKLKEKQLKARLLLQVHDELIFEAPKEEIEILEKLVPEVM EHALALDVPLKVDFASGPSWYDAK*" gene complement(2838780..2841422) /gene="polA" /locus_tag="BSU_29090" /old_locus_tag="BSU29090" promotor_-10 complement(2841477..2841496) /Source="Nicolas_upshift_promotors" /id="U2248" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.778221778221778" /psig=1 /xcortree=1979 /SigmaFactorBS="cttttttgtgtcttctcttatagttcacgTATTTTCCtttca aattgaacTTTGTTAAAATAAGAGGAGCtaatgactatgtaagagatgaatggaagcc t" /listShort="polA, mutM, S1096, ytaF, coaE" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2841486) /Source="Nicolas_upshifts" /id="U2248" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.778221778221778" /psig=1 /xcortree=1979 /SigmaFactorBS="cttttttgtgtcttctcttatagttcacgTATTTTCCtttca aattgaacTTTGTTAAAATAAGAGGAGCtaatgactatgtaagagatgaatggaagcc t" /listShort="polA, mutM, S1096, ytaF, coaE" /GFF_Attribute="listLong" promotor_-35 complement(2841510..2841517) /Source="Nicolas_upshift_promotors" /id="U2248" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.778221778221778" /psig=1 /xcortree=1979 /SigmaFactorBS="cttttttgtgtcttctcttatagttcacgTATTTTCCtttca aattgaacTTTGTTAAAATAAGAGGAGCtaatgactatgtaagagatgaatggaagcc t" /listShort="polA, mutM, S1096, ytaF, coaE" /GFF_Attribute="listLong" /label="promotor_-35" S_feature complement(2841546..2841665) /Source="Nicolas_S_feature" /locus_tag="new_2975948_2976067_c" /HighExp="M0t90, M40t90, M9-stat, Lbstat, Sw, T1.30H, T1.0H, S4, S3, S5" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="0.995, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S1097" downshifts complement(2841589) /Source="Nicolas_upshifts" /id="D1491" /incds=0 /nref=48 /ntot=175 /MaxReadThrough="5.58383" /MaxDrop="3.85702" /score="15.0073484" /energy="-12.2" /TU="U2249" /idTUdmin="U2254" /TUdmin="-3" /isTUend="TRUE" CDS complement(2841666..2843405) /gene="phoR" /locus_tag="BSU_29100" /old_locus_tag="BSU29100" /function="16.3: Control" /function="16.12: Sense" /experiment="publication(s) with functional evidences, PMID:10433720, 12486063, 14762014, 15205429, 16430694, 16452408, 17085571, 20487291, 23145827, 25315493, 25355628" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10433720, 12486063, 14762014, 15205429, 16430694, 16452408, 17085571, 20487291, 23145827, 25315493, 25355628; Product type rc : receptor" /codon_start=1 /transl_table=11 /product="two-component sensor histidine kinase" /protein_id="NP_390788.1" /db_xref="EnsemblGenomes-Gn:BSU29100" /db_xref="EnsemblGenomes-Tr:CAB14870" /db_xref="GOA:P23545" /db_xref="InterPro:IPR000014" /db_xref="InterPro:IPR003594" /db_xref="InterPro:IPR003661" /db_xref="InterPro:IPR004358" /db_xref="InterPro:IPR005467" /db_xref="InterPro:IPR013767" /db_xref="InterPro:IPR031967" /db_xref="InterPro:IPR035965" /db_xref="InterPro:IPR036097" /db_xref="InterPro:IPR036890" /db_xref="PDB:3CWF" /db_xref="SubtiList:BG10364" /db_xref="UniProtKB/Swiss-Prot:P23545" /translation="MNKYRVRLFSVFVVCMILVFCVLGLFLQQLFETSDQRKAEEHIE KEAKYLASLLDAGNLNNQANEKIIKDAGGALDVSASVIDTDGKVLYGSNGRSADSQKV QALVSGHEGILSTTDNKLYYGLSLRSEGEKTGYVLLSASEKSDGLKGELWGMLTASLC TAFIVIVYFYSSMTSRYKRSIESATNVATELSKGNYDARTYGGYIRRSDKLGHAMNSL AIDLMEMTRTQEMQRDRLLTVIENIGSGLIMIDGRGFINLVNRSYAKQFHINPNHMLR RLYHDAFEHEEVIQLVEDIFMTETKKCKLLRLPIKIERRYFEVDGVPIMGPDDEWKGI VLVFHDMTETKKLEQMRKDFVANVSHELKTPITSIKGFTETLLDGAMEDKEALSEFLS IILKESERLQSLVQDLLDLSKIEQQNFTLSIETFEPAKMLGEIETLLKHKADEKGISL HLNVPKDPQYVSGDPYRLKQVFLNLVNNALTYTPEGGSVAINVKPREKDIQIEVADSG IGIQKEEIPRIFERFYRVDKDRSRNSGGTGLGLAIVKHLIEAHEGKIDVTSELGRGTV FTVTLKRAAEKSA*" gene complement(2841666..2843405) /gene="phoR" /locus_tag="BSU_29100" /old_locus_tag="BSU29100" CDS complement(2843398..2844120) /gene="phoP" /locus_tag="BSU_29110" /old_locus_tag="BSU29110" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:14762014, 14973033, 15205429, 16030210, 16452408, 16816204, 16980498, 17085571, 20487291, 22720735, 23145827, 25315493, 25355628" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 14762014, 14973033, 15205429, 16030210, 16452408, 16816204, 16980498, 17085571, 20487291, 22720735, 23145827, 25315493, 25355628; Product type r: regulator" /codon_start=1 /transl_table=11 /product="two-component response regulator" /protein_id="NP_390789.2" /db_xref="EnsemblGenomes-Gn:BSU29110" /db_xref="EnsemblGenomes-Tr:CAB14871" /db_xref="GOA:P13792" /db_xref="InterPro:IPR001789" /db_xref="InterPro:IPR001867" /db_xref="InterPro:IPR011006" /db_xref="InterPro:IPR016032" /db_xref="InterPro:IPR036388" /db_xref="PDB:1MVO" /db_xref="SubtiList:BG10363" /db_xref="UniProtKB/Swiss-Prot:P13792" /translation="MNKKILVVDDEESIVTLLQYNLERSGYDVITASDGEEALKKAET EKPDLIVLDVMLPKLDGIEVCKQLRQQKLMFPILMLTAKDEEFDKVLGLELGADDYMT KPFSPREVNARVKAILRRSEIAAPSSEMKNDEMEGQIVIGDLKILPDHYEAYFKESQL ELTPKEFELLLYLGRHKGRVLTRDLLLSAVWNYDFAGDTRIVDVHISHLRDKIENNTK KPIYIKTIRGLGYKLEEPKMNE*" gene complement(2843398..2844120) /gene="phoP" /locus_tag="BSU_29110" /old_locus_tag="BSU29110" promotor_-10 complement(2844188..2844207) /Source="Nicolas_upshift_promotors" /id="U2249" /multdbtbs="SigA,SigA,SigE" /comp="M19" /sig="SigA" /pcomp="0.427572427572428" /psig="0.995004995004995" /xcortree=1405 /SigmaFactorBS="tttatttcttttaaaaatgatgtaaaaggcgAATTGTCggaa tgtcctgctTTCGCTAAAATAAAATCATGaaacatgttaagatgacataaaatagaga a" /listShort="phoP, phoR, S1097, polA, mutM, S1096, ytaF, coaE" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2844198) /Source="Nicolas_upshifts" /id="U2249" /multdbtbs="SigA,SigA,SigE" /comp="M19" /sig="SigA" /pcomp="0.427572427572428" /psig="0.995004995004995" /xcortree=1405 /SigmaFactorBS="tttatttcttttaaaaatgatgtaaaaggcgAATTGTCggaa tgtcctgctTTCGCTAAAATAAAATCATGaaacatgttaagatgacataaaatagaga a" /listShort="phoP, phoR, S1097, polA, mutM, S1096, ytaF, coaE" /GFF_Attribute="listLong" S_feature complement(2844200..2844300) /Source="Nicolas_S_feature" /locus_tag="new_2978602_2978702_c" /HighExp="M40t90, T1.30H, T1.0H, M0t90, M9-stat, T2.0H, T2.30H, T3.0H, T0.30H, T3.30H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="1, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S1098" promotor_-35 complement(2844221..2844227) /Source="Nicolas_upshift_promotors" /id="U2249" /multdbtbs="SigA,SigA,SigE" /comp="M19" /sig="SigA" /pcomp="0.427572427572428" /psig="0.995004995004995" /xcortree=1405 /SigmaFactorBS="tttatttcttttaaaaatgatgtaaaaggcgAATTGTCggaa tgtcctgctTTCGCTAAAATAAAATCATGaaacatgttaagatgacataaaatagaga a" /listShort="phoP, phoR, S1097, polA, mutM, S1096, ytaF, coaE" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2844332..2845270) /gene="mdh" /locus_tag="BSU_29120" /old_locus_tag="BSU29120" /EC_number="1.1.1.37" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:6319195, 8550482, 12034826, 16788182, 22720735, 23136871, 24325460, 25355936" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 6319195, 8550482, 12034826, 16788182, 22720735, 23136871, 24325460, 25355936; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="malate dehydrogenase (NAD-dependent)" /protein_id="NP_390790.1" /db_xref="EnsemblGenomes-Gn:BSU29120" /db_xref="EnsemblGenomes-Tr:CAB14872" /db_xref="GOA:P49814" /db_xref="InterPro:IPR001236" /db_xref="InterPro:IPR001557" /db_xref="InterPro:IPR011275" /db_xref="InterPro:IPR015955" /db_xref="InterPro:IPR022383" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG11386" /db_xref="UniProtKB/Swiss-Prot:P49814" /translation="MGNTRKKVSVIGAGFTGATTAFLIAQKELADVVLVDIPQLENPT KGKALDMLEASPVQGFDAKITGTSNYEDTAGSDIVVITAGIARKPGMSRDDLVSTNEK IMRSVTQEIVKYSPDSIIVVLTNPVDAMTYAVYKESGFPKERVIGQSGVLDTARFRTF VAEELNLSVKDVTGFVLGGHGDDMVPLVRYSYAGGIPLETLIPKERIDAIVERTRKGG GEIVNLLGNGSAYYAPAASLTEMVEAILKDQRRVLPTIAYLEGEYGYEGIYLGVPTIV GGNGLEQIIELELTDYERAQLNKSVESVKNVMKVLS*" gene complement(2844332..2845270) /gene="mdh" /locus_tag="BSU_29120" /old_locus_tag="BSU29120" downshifts complement(2844345) /Source="Nicolas_upshifts" /id="D1492" /incds=0 /nref=200 /ntot=242 /MaxReadThrough="8.27126" /MaxDrop="7.40884" /score="-0.758981483" /energy="-13.5" /TU="U2251,U2254" /idTUdmin="U2250" /TUdmin="-9" /isTUend="TRUE" CDS complement(2845314..2846585) /gene="icd" /locus_tag="BSU_29130" /old_locus_tag="BSU29130" /EC_number="1.1.1.42" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:8045898, 9244258, 11290745, 24325460" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8045898, 9244258, 11290745, 24325460; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="isocitrate dehydrogenase" /protein_id="NP_390791.1" /db_xref="EnsemblGenomes-Gn:BSU29130" /db_xref="EnsemblGenomes-Tr:CAB14873" /db_xref="GOA:P39126" /db_xref="InterPro:IPR004439" /db_xref="InterPro:IPR019818" /db_xref="InterPro:IPR024084" /db_xref="PDB:1HQS" /db_xref="SubtiList:BG10856" /db_xref="UniProtKB/Swiss-Prot:P39126" /translation="MAQGEKITVSNGVLNVPNNPIIPFIEGDGTGPDIWNAASKVLEA AVEKAYKGEKKITWKEVYAGEKAYNKTGEWLPAETLDVIREYFIAIKGPLTTPVGGGI RSLNVALRQELDLFVCLRPVRYFTGVPSPVKRPEDTDMVIFRENTEDIYAGIEYAKGS EEVQKLISFLQNELNVNKIRFPETSGIGIKPVSEEGTSRLVRAAIDYAIEHGRKSVTL VHKGNIMKFTEGAFKNWGYELAEKEYGDKVFTWAQYDRIAEEQGKDAANKAQSEAEAA GKIIIKDSIADIFLQQILTRPNEFDVVATMNLNGDYISDALAAQVGGIGIAPGANINY ETGHAIFEATHGTAPKYAGLDKVNPSSVILSGVLLLEHLGWNEAADLVIKSMEKTIAS KVVTYDFARLMDGATEVKCSEFGEELIKNMD*" gene complement(2845314..2846585) /gene="icd" /locus_tag="BSU_29130" /old_locus_tag="BSU29130" misc_feature complement(2846370..2846389) /Source="Nicolas_upshift_promotors" /id="U2250" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.46953046953047" /psig="0.95004995004995" /xcortree=3208 /SigmaFactorBS="agcatacaaaggcgaaaagaaaattacatggaaagaagttta cgccggagaaaAGGCTTATAATAAAACAGGTgagtggctccctgctgaaacattagat g" /listShort="mdh" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(2846382) /Source="Nicolas_upshifts" /id="U2250" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.46953046953047" /psig="0.95004995004995" /xcortree=3208 /SigmaFactorBS="agcatacaaaggcgaaaagaaaattacatggaaagaagttta cgccggagaaaAGGCTTATAATAAAACAGGTgagtggctccctgctgaaacattagat g" /listShort="mdh" /GFF_Attribute="listLong" S_feature complement(2846586..2846668) /Source="Nicolas_S_feature" /locus_tag="new_2980988_2981070_c" /HighExp="T2.30H, M40t90, T1.0H, T-3.40H, HiOs, T3.30H, T3.0H, T0.0H, Lbstat, T-5.40H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="1, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S1099" upshifts complement(2846668) /Source="Nicolas_upshifts" /id="U2251" /multdbtbs="SigA" /comp="M16" /sig="SigA" /pcomp="0.568431568431568" /psig=1 /xcortree=3209 /SigmaFactorBS="tgcgtcaatgaggttagccTCTTGttcagacatcaaaatTGG GTTACACTTTAAATTGAatgttaggaaaaatcattttattttctatataagaaaaata a" /listShort="S1099, icd, mdh, S1098" /listLong="phoP, phoR" S_feature complement(2846670..2846748) /Source="Nicolas_S_feature" /locus_tag="new_2981072_2981150_c" /HighExp="T2.30H, T3.30H, T1.0H, M40t90, T3.0H, Lbstat, M0t90, T0.0H, HiOs, T-0.40H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1100" promotor_-10 complement(2846670..2846689) /Source="Nicolas_upshift_promotors" /id="U2251" /multdbtbs="SigA" /comp="M16" /sig="SigA" /pcomp="0.568431568431568" /psig=1 /xcortree=3209 /SigmaFactorBS="tgcgtcaatgaggttagccTCTTGttcagacatcaaaatTGG GTTACACTTTAAATTGAatgttaggaaaaatcattttattttctatataagaaaaata a" /listShort="S1099, icd, mdh, S1098" /listLong="phoP, phoR" /label="promotor_-10" promotor_-35 complement(2846705..2846709) /Source="Nicolas_upshift_promotors" /id="U2251" /multdbtbs="SigA" /comp="M16" /sig="SigA" /pcomp="0.568431568431568" /psig=1 /xcortree=3209 /SigmaFactorBS="tgcgtcaatgaggttagccTCTTGttcagacatcaaaatTGG GTTACACTTTAAATTGAatgttaggaaaaatcattttattttctatataagaaaaata a" /listShort="S1099, icd, mdh, S1098" /listLong="phoP, phoR" /label="promotor_-35" CDS complement(2846749..2847867) /gene="citZ" /locus_tag="BSU_29140" /old_locus_tag="BSU29140" /EC_number="2.3.3.16" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:8655569, 10656796, 11985717, 12100558, 19202299, 22720735, 23139400, 23354745" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8655569, 10656796, 11985717, 12100558, 19202299, 22720735, 23139400, 23354745; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="citrate synthase II" /protein_id="NP_390792.1" /db_xref="EnsemblGenomes-Gn:BSU29140" /db_xref="EnsemblGenomes-Tr:CAB14874" /db_xref="GOA:P39120" /db_xref="InterPro:IPR002020" /db_xref="InterPro:IPR011278" /db_xref="InterPro:IPR016142" /db_xref="InterPro:IPR019810" /db_xref="InterPro:IPR024176" /db_xref="InterPro:IPR036969" /db_xref="SubtiList:BG10855" /db_xref="UniProtKB/Swiss-Prot:P39120" /translation="MTATRGLEGVVATTSSVSSIIDDTLTYVGYDIDDLTENASFEEI IYLLWHLRLPNKKELEELKQQLAKEAAVPQEIIEHFKSYSLENVHPMAALRTAISLLG LLDSEADTMNPEANYRKAIRLQAKVPGLVAAFSRIRKGLEPVEPREDYGIAENFLYTL NGEEPSPIEVEAFNKALILHADHELNASTFTARVCVATLSDIYSGITAAIGALKGPLH GGANEGVMKMLTEIGEVENAEPYIRAKLEKKEKIMGFGHRVYKHGDPRAKHLKEMSKR LTNLTGESKWYEMSIRIEDIVTSEKKLPPNVDFYSASVYHSLGIDHDLFTPIFAVSRM SGWLAHILEQYDNNRLIRPRADYTGPDKQKFVPIEERA*" gene complement(2846749..2847867) /gene="citZ" /locus_tag="BSU_29140" /old_locus_tag="BSU29140" downshifts 2847362 /Source="Nicolas_upshifts" /id="D1493" /incds=1 /nref=2 /ntot=63 /MaxReadThrough="1.41638" /MaxDrop="3.70762" /score="40.6931963" /energy="-9.9" /TU="NA" /idTUdmin="U2252" /TUdmin="-506" /isTUend="FALSE" misc_feature 2847709..2847712 /Source="Nicolas_upshift_promotors" /id="U2252" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.985014985014985" /psig="0.002997002997003" /xcortree=74 /SigmaFactorBS="cagcttcctttgcaagctgctgctttaactcttcaagctctt ttttgtttggCAGCcttagatgccaaagcaagtagatgatttcttcaaaacttgcatt c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 2847717 /Source="Nicolas_upshifts" /id="U2252" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.985014985014985" /psig="0.002997002997003" /xcortree=74 /SigmaFactorBS="cagcttcctttgcaagctgctgctttaactcttcaagctctt ttttgtttggCAGCcttagatgccaaagcaagtagatgatttcttcaaaacttgcatt c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" downshifts 2847846 /Source="Nicolas_upshifts" /id="D1494" /incds=0 /nref=1 /ntot=126 /MaxReadThrough="2.98678" /MaxDrop="3.07929" /score="40.6931963" /energy="-9.9" /TU="U2252" /idTUdmin="U2252" /TUdmin="-22" /isTUend="TRUE" S_feature complement(2847868..2848074) /Source="Nicolas_S_feature" /locus_tag="new_2982270_2982476_c" /HighExp="T3.0H, T3.30H, T2.30H, T4.0H, M0t90, T2.0H, T1.30H, T5.0H, BC, Pyr" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1101" misc_feature 2848042..2848054 /Source="Nicolas_upshift_promotors" /id="U2253" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.467532467532468" /psig="0.464535464535465" /xcortree=721 /SigmaFactorBS="ctggaactaaaaccctttgcttttgaaagaacataacaaatt tttataaGCTTATTTAAGTTtaagcctattctcattataaacaataatcagacatttg t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 2848053 /Source="Nicolas_upshifts" /id="U2253" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.467532467532468" /psig="0.464535464535465" /xcortree=721 /SigmaFactorBS="ctggaactaaaaccctttgcttttgaaagaacataacaaatt tttataaGCTTATTTAAGTTtaagcctattctcattataaacaataatcagacatttg t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 complement(2848060..2848079) /Source="Nicolas_upshift_promotors" /id="U2254" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.573426573426573" /psig=1 /xcortree=493 /SigmaFactorBS="aaatcacagaatggaaaaaaaaaattataggtaaacATTTAa caaatgtctgattATTGTTTATAATGAGAATAGgcttaaacttaaataagcttataaa a" /listShort="S1101, citZ, S1100, S1099, icd, mdh, S1098, phoP, phoR, S1097" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2848074) /Source="Nicolas_upshifts" /id="U2254" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.573426573426573" /psig=1 /xcortree=493 /SigmaFactorBS="aaatcacagaatggaaaaaaaaaattataggtaaacATTTAa caaatgtctgattATTGTTTATAATGAGAATAGgcttaaacttaaataagcttataaa a" /listShort="S1101, citZ, S1100, S1099, icd, mdh, S1098, phoP, phoR, S1097" /GFF_Attribute="listLong" promotor_-35 complement(2848094..2848098) /Source="Nicolas_upshift_promotors" /id="U2254" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.573426573426573" /psig=1 /xcortree=493 /SigmaFactorBS="aaatcacagaatggaaaaaaaaaattataggtaaacATTTAa caaatgtctgattATTGTTTATAATGAGAATAGgcttaaacttaaataagcttataaa a" /listShort="S1101, citZ, S1100, S1099, icd, mdh, S1098, phoP, phoR, S1097" /GFF_Attribute="listLong" /label="promotor_-35" downshifts complement(2848194) /Source="Nicolas_upshifts" /id="D1495" /incds=0 /nref=116 /ntot=204 /MaxReadThrough="6.4946" /MaxDrop="5.00031" /score="29.3344463" /energy="-8.1" /TU="NA" /idTUdmin="U2255" /TUdmin=14 /isTUend="TRUE" CDS complement(2848201..2848665) /gene="ytwI" /locus_tag="BSU_29150" /old_locus_tag="BSU29150" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative integral membrane protein" /protein_id="NP_390793.1" /db_xref="EnsemblGenomes-Gn:BSU29150" /db_xref="EnsemblGenomes-Tr:CAB14875" /db_xref="GOA:O34811" /db_xref="InterPro:IPR007382" /db_xref="SubtiList:BG13933" /db_xref="UniProtKB/Swiss-Prot:O34811" /translation="MFTQANLFLILLLAIALIAKNQSLLFAVSVLLIIKIVGLDQKLF PTIQSKGINWGVTIITIAVLVPIATGEIGFKQLGEAMRSSYAWIALGAGIAVALIAKN GLTLLENDPHITTALVIGTILAVALFGGVAVGPLIGAGIAYLAMQIVKLFTS*" gene complement(2848201..2848665) /gene="ytwI" /locus_tag="BSU_29150" /old_locus_tag="BSU29150" promotor_-10 complement(2848678..2848697) /Source="Nicolas_upshift_promotors" /id="U2255" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.774225774225774" /psig="0.774225774225774" /xcortree=1276 /SigmaFactorBS="cctcctctcgtcagcatgtcctattttttatatgTATTCACG CtgcggctgaataTGAATACATTCATCTTAAAGgagggatggcatgtgtttacacaag c" /listShort="ytwI" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2848692) /Source="Nicolas_upshifts" /id="U2255" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.774225774225774" /psig="0.774225774225774" /xcortree=1276 /SigmaFactorBS="cctcctctcgtcagcatgtcctattttttatatgTATTCACG CtgcggctgaataTGAATACATTCATCTTAAAGgagggatggcatgtgtttacacaag c" /listShort="ytwI" /GFF_Attribute="listLong" S_feature complement(2848694..2849879) /Source="Nicolas_S_feature" /locus_tag="new_2983096_2984281_c" /HighExp="G135, G180, LBGstat, G150, LBGtran, S0, Paraq, Oxctl, H2O2, LBGexp" /AntisenseName="ytvI" /AntisenseCor="-0.73323145377324295" /AntisenseRegPval="-45.9" /CDS_PredictionProba="NA" /TUshortSig="NA" /TUshortPSig="NA" /TUlongSig="NA" /TUlongPSig="NA" /label="S1102" promotor_-35 2848694..2848699 /Source="Nicolas_upshift_promotors" /id="U2256" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=994 /SigmaFactorBS="aaacacatgccatccctcctttaagatgaatgtaTTCATAtt cagccgcagcgtGAATACATATAAAAAATAGgacatgctgacgagaggaggaccgttt t" /listShort="ytvI" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 complement(2848710..2848718) /Source="Nicolas_upshift_promotors" /id="U2255" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.774225774225774" /psig="0.774225774225774" /xcortree=1276 /SigmaFactorBS="cctcctctcgtcagcatgtcctattttttatatgTATTCACG CtgcggctgaataTGAATACATTCATCTTAAAGgagggatggcatgtgtttacacaag c" /listShort="ytwI" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2848714..2848732 /Source="Nicolas_upshift_promotors" /id="U2256" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=994 /SigmaFactorBS="aaacacatgccatccctcctttaagatgaatgtaTTCATAtt cagccgcagcgtGAATACATATAAAAAATAGgacatgctgacgagaggaggaccgttt t" /listShort="ytvI" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2848720 /Source="Nicolas_upshifts" /id="U2256" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=994 /SigmaFactorBS="aaacacatgccatccctcctttaagatgaatgtaTTCATAtt cagccgcagcgtGAATACATATAAAAAATAGgacatgctgacgagaggaggaccgttt t" /listShort="ytvI" /GFF_Attribute="listLong" CDS 2848762..2849877 /gene="ytvI" /locus_tag="BSU_29160" /old_locus_tag="BSU29160" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 12662922, 15849754, 16850406, 26735940; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative sporulation-related permease" /protein_id="NP_390794.1" /db_xref="EnsemblGenomes-Gn:BSU29160" /db_xref="EnsemblGenomes-Tr:CAB14876" /db_xref="GOA:O34991" /db_xref="InterPro:IPR002549" /db_xref="InterPro:IPR014227" /db_xref="SubtiList:BG13930" /db_xref="UniProtKB/Swiss-Prot:O34991" /translation="MNQSYITIFFRTLFVISMTAGSIAAAYYSFPLTYPFLIALILSS VIHPVVDYLDKVTGFPRTINVLGVLAFFLLAAFGVLTILVAEIVTGTAYLAKTLPPHI STFISYCEKLFTTHIQPLYNELTLLFQELETNQQASIVTHIQTLGDSAAKNAGLLLSH ILEMIPRFFALLPNTAAVLIFSLLATFFMTKDWHKLKAMLVLILPDRVTANSKAISSE LKKAMTGFIKAQAVLVFITMVIVFIGLSLLKVEHAATIAFLIGLVDLLPYLGAGSVFV PWILYLSITGQLPQAIGIGILYLVVLIQRQLTEPKILSKSIGIDPLATLIALFAGFKL FGFLGLIAGPAVLVIIQAFITTGALKEIWSYITVQQK*" gene 2848762..2849877 /gene="ytvI" /locus_tag="BSU_29160" /old_locus_tag="BSU29160" downshifts 2849848 /Source="Nicolas_upshifts" /id="D1496" /incds=0 /nref=2 /ntot=24 /MaxReadThrough="1.639" /MaxDrop="3.31897" /score="37.6858539" /energy="-16.7" /TU="NA" /idTUdmin="U2256" /TUdmin=0 /isTUend="TRUE" CDS complement(2849910..2850293) /gene="ytzA" /locus_tag="BSU_29170" /old_locus_tag="BSU29170" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15302217, 15849754, 16850406; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative integral inner membrane protein" /protein_id="NP_390795.1" /db_xref="EnsemblGenomes-Gn:BSU29170" /db_xref="EnsemblGenomes-Tr:CAB14877" /db_xref="GOA:O32064" /db_xref="InterPro:IPR007313" /db_xref="SubtiList:BG13935" /db_xref="UniProtKB/Swiss-Prot:O32064" /translation="MRFLFLLFIVFPAIEIGIFLFLGNLIGILPTVLFMILTGIIGAA AAKKQGTEVYYKVQRDLQYGKMPGEAIADGLCIFIGGLLLMLPGFLSDLAGACLLIPF TRGWCKPILFKWLRGMSKNKRIIIK*" gene complement(2849910..2850293) /gene="ytzA" /locus_tag="BSU_29170" /old_locus_tag="BSU29170" downshifts complement(2849924) /Source="Nicolas_upshifts" /id="D1497" /incds=0 /nref=181 /ntot=256 /MaxReadThrough="4.28884" /MaxDrop="5.74703" /score="18.319512" /energy="-13.8" /TU="NA" /idTUdmin="U2257" /TUdmin=0 /isTUend="TRUE" S_feature complement(2850294..2850385) /Source="Nicolas_S_feature" /locus_tag="new_2984696_2984787_c" /HighExp="G135, LBGtran, G150, LBGexp, M0t45, Lbexp, S0, G180, Oxctl, Lbtran" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA, SigA" /TUshortPSig="1, 1, 1" /TUlongSig="SigA, SigA" /TUlongPSig="1, 1" /label="S1103" CDS complement(2850386..2852143) /gene="pyk" /locus_tag="BSU_29180" /old_locus_tag="BSU29180" /EC_number="2.7.1.40" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:10559165, 10932722, 10966427, 11489127, 17022686, 18586936, 22846916, 24825009" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10559165, 10932722, 10966427, 11489127, 17022686, 18586936, 22846916, 24825009; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="pyruvate kinase" /protein_id="NP_390796.1" /db_xref="EnsemblGenomes-Gn:BSU29180" /db_xref="EnsemblGenomes-Tr:CAB14878" /db_xref="GOA:P80885" /db_xref="InterPro:IPR001697" /db_xref="InterPro:IPR008279" /db_xref="InterPro:IPR011037" /db_xref="InterPro:IPR015793" /db_xref="InterPro:IPR015795" /db_xref="InterPro:IPR015813" /db_xref="InterPro:IPR018209" /db_xref="InterPro:IPR036918" /db_xref="SubtiList:BG12661" /db_xref="UniProtKB/Swiss-Prot:P80885" /translation="MRKTKIVCTIGPASESIEMLTKLMESGMNVARLNFSHGDFEEHG ARIKNIREASKKLGKNVGILLDTKGPEIRTHTMENGGIELETGKELIISMDEVVGTTD KISVTYEGLVHDVEQGSTILLDDGLIGLEVLDVDAAKREIKTKVLNNGTLKNKKGVNV PGVSVNLPGITEKDARDIVFGIEQGVDFIAPSFIRRSTDVLEIRELLEEHNAQDIQII PKIENQEGVDNIDAILEVSDGLMVARGDLGVEIPAEEVPLVQKELIKKCNALGKPVIT ATQMLDSMQRNPRPTRAEASDVANAIFDGTDAIMLSGETAAGSYPVEAVQTMHNIASR SEEALNYKEILSKRRDQVGMTITDAIGQSVAHTAINLNAAAIVTPTESGHTARMIAKY RPQAPIVAVTVNDSISRKLALVSGVFAESGQNASSTDEMLEDAVQKSLNSGIVKHGDL IVITAGTVGESGTTNLMKVHTVGDIIAKGQGIGRKSAYGPVVVAQNAKEAEQKMTDGA VLVTKSTDRDMIASLEKASALITEEGGLTSHAAVVGLSLGIPVIVGLENATSILTDGQ DITVDASRGAVYQGRASVL*" gene complement(2850386..2852143) /gene="pyk" /locus_tag="BSU_29180" /old_locus_tag="BSU29180" CDS complement(2852186..2853145) /gene="pfkA" /locus_tag="BSU_29190" /old_locus_tag="BSU29190" /EC_number="2.7.1.11" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:12450869, 12622823, 12682299, 19193632, 20473954, 22198292" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12450869, 12622823, 12682299, 19193632, 20473954, 22198292; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="6-phosphofructokinase" /protein_id="NP_390797.1" /db_xref="EnsemblGenomes-Gn:BSU29190" /db_xref="EnsemblGenomes-Tr:CAB14879" /db_xref="GOA:O34529" /db_xref="InterPro:IPR000023" /db_xref="InterPro:IPR012003" /db_xref="InterPro:IPR012828" /db_xref="InterPro:IPR015912" /db_xref="InterPro:IPR022953" /db_xref="InterPro:IPR035966" /db_xref="PDB:4A3S" /db_xref="SubtiList:BG12644" /db_xref="UniProtKB/Swiss-Prot:O34529" /translation="MKRIGVLTSGGDSPGMNAAVRAVVRKAIYHDVEVYGIYNGYAGL ISGKIEKLELGSVGDIIHRGGTKLYTARCPEFKTVEGREKGIANLKKLGIEGLVVIGG DGSYMGAKKLTEHGFPCVGVPGTIDNDIPGTDFTIGFDTALNTVIDAIDKIRDTATSH ERTYVIEVMGRHAGDIALWAGLAGGAESILIPEADYDMHEIIARLKRGHERGKKHSII IVAEGVGSGVEFGKRIEEETNLETRVSVLGHIQRGGSPSAADRVLASRLGAYAVELLL EGKGGRCVGIQNNKLVDHDIIEILETKHTVEQNMYQLSKELSI*" gene complement(2852186..2853145) /gene="pfkA" /locus_tag="BSU_29190" /old_locus_tag="BSU29190" S_feature complement(2853146..2853247) /Source="Nicolas_S_feature" /locus_tag="new_2987548_2987649_c" /HighExp="G150, LBGtran, LBGexp, Lbexp, dia0, G180, G135, Oxctl, LBGstat, Paraq" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA, SigA" /TUshortPSig="1, 1, 1" /TUlongSig="SigA, SigA" /TUlongPSig="1, 1" /label="S1104" promotor_-10 complement(2853236..2853255) /Source="Nicolas_upshift_promotors" /id="U2257" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.967032967032967" /psig=1 /xcortree=2698 /SigmaFactorBS="cacgtttattttttgtgacattccttaaatttTATTTaaaaa caatttatttAATTGTATAATAGGTAAGGTttcatagggaggatggagatcccttttc a" /listShort="S1104, pfkA, pyk, S1103, ytzA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2853247) /Source="Nicolas_upshifts" /id="U2257" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.967032967032967" /psig=1 /xcortree=2698 /SigmaFactorBS="cacgtttattttttgtgacattccttaaatttTATTTaaaaa caatttatttAATTGTATAATAGGTAAGGTttcatagggaggatggagatcccttttc a" /listShort="S1104, pfkA, pyk, S1103, ytzA" /GFF_Attribute="listLong" promotor_-35 complement(2853271..2853275) /Source="Nicolas_upshift_promotors" /id="U2257" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.967032967032967" /psig=1 /xcortree=2698 /SigmaFactorBS="cacgtttattttttgtgacattccttaaatttTATTTaaaaa caatttatttAATTGTATAATAGGTAAGGTttcatagggaggatggagatcccttttc a" /listShort="S1104, pfkA, pyk, S1103, ytzA" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2853329..2854306) /gene="accA" /locus_tag="BSU_29200" /old_locus_tag="BSU29200" /EC_number="6.4.1.2" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 11133475, 12682299, 15066985; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="acetyl-CoA carboxylase (carboxyltransferase alpha subunit)" /protein_id="NP_390798.1" /db_xref="EnsemblGenomes-Gn:BSU29200" /db_xref="EnsemblGenomes-Tr:CAB14880" /db_xref="GOA:O34847" /db_xref="InterPro:IPR001095" /db_xref="InterPro:IPR011763" /db_xref="InterPro:IPR029045" /db_xref="SubtiList:BG12557" /db_xref="UniProtKB/Swiss-Prot:O34847" /translation="MAPRLEFEKPVIELQTKIAELKKFTQDSDMDLSAEIERLEDRLA KLQDDIYKNLKPWDRVQIARLADRPTTLDYIEHLFTDFFECHGDRAYGDDEAIVGGIA KFHGLPVTVIGHQRGKDTKENLVRNFGMPHPEGYRKALRLMKQADKFNRPIICFIDTK GAYPGRAAEERGQSEAIAKNLFEMAGLRVPVICIVIGEGGSGGALGLGVGNHLHMLEN STYSVISPEGAAALLWKDSSLAKKAAETMKITAPDLKELGIIDHMIKEVKGGAHHDVK LQASYMDETLKQSLKTLLKLSEEELVQQRYEKYKAIGKVSVEDQYIGVN*" gene complement(2853329..2854306) /gene="accA" /locus_tag="BSU_29200" /old_locus_tag="BSU29200" downshifts complement(2853356) /Source="Nicolas_upshifts" /id="D1498" /incds=0 /nref=48 /ntot=176 /MaxReadThrough="5.40549" /MaxDrop="5.53933" /score="-3.96100458" /energy="-6.8" /TU="U2259,U2260,U2262,U2263" /idTUdmin="U2260" /TUdmin="-88" /isTUend="FALSE" CDS complement(2854291..2855163) /gene="accD" /locus_tag="BSU_29210" /old_locus_tag="BSU29210" /EC_number="6.4.1.2" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 11133475, 12682299, 14594796, 15066985; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="acetyl-CoA carboxylase (carboxyltransferase betasubunit)" /protein_id="NP_390799.2" /db_xref="EnsemblGenomes-Gn:BSU29210" /db_xref="EnsemblGenomes-Tr:CAB14881" /db_xref="GOA:C0SP93" /db_xref="InterPro:IPR000438" /db_xref="InterPro:IPR011762" /db_xref="InterPro:IPR029045" /db_xref="InterPro:IPR034733" /db_xref="SubtiList:BG13926" /db_xref="UniProtKB/Swiss-Prot:C0SP93" /translation="MLKDIFTKKKKYASVPSDQAKHDVPEGIMTKCPKCKKIMLTKEL DKNMRVCMNCDYHFPMNAKQRIESLMDEQSFEEFNQGMLSENPLGFPGYLEKLEKDRE KTSLNEAVVTGKGTIGGHPAVVAVMDSSFRMGSMGSVVGEKITLAIEKAKADKVPFII FTASGGARMQEGVLSLMQMAKTSSALKLFSEEQGLIISVMTHPTTGGVSASFASLGDY NFAEPGALIGFAGRRIIEQTIGEKLPEDFQTAEFLLKHGQLDAVIHRDDMKKTLENLL DMHQTGGDIEWLQD*" gene complement(2854291..2855163) /gene="accD" /locus_tag="BSU_29210" /old_locus_tag="BSU29210" promotor_-35 2855125..2855130 /Source="Nicolas_upshift_promotors" /id="U2258" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.993006993006993" /psig="0.993006993006993" /xcortree=1067 /SigmaFactorBS="ggaacatcgtgcttcgcttgatcagacggtacggaAGCATAc tttttctttttcgtGAATATATCCTTTAACAAAtgattacctcccttttgtgaagggt t" /listShort="S1105" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2855146..2855164 /Source="Nicolas_upshift_promotors" /id="U2258" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.993006993006993" /psig="0.993006993006993" /xcortree=1067 /SigmaFactorBS="ggaacatcgtgcttcgcttgatcagacggtacggaAGCATAc tttttctttttcgtGAATATATCCTTTAACAAAtgattacctcccttttgtgaagggt t" /listShort="S1105" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 2855150..2856324 /Source="Nicolas_S_feature" /locus_tag="new_2989552_2990726" /HighExp="S5, S8, S6, S7, C30, S4, C90, S3, T5.0H, BC" /AntisenseName="ytsJ" /AntisenseCor="-0.46008986922877199" /AntisenseRegPval="-14.8" /CDS_PredictionProba="NA" /TUshortSig="SigEF" /TUshortPSig="0.993" /TUlongSig="NA" /TUlongPSig="NA" /label="S1105" upshifts 2855150 /Source="Nicolas_upshifts" /id="U2258" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.993006993006993" /psig="0.993006993006993" /xcortree=1067 /SigmaFactorBS="ggaacatcgtgcttcgcttgatcagacggtacggaAGCATAc tttttctttttcgtGAATATATCCTTTAACAAAtgattacctcccttttgtgaagggt t" /listShort="S1105" /GFF_Attribute="listLong" S_feature complement(2855164..2855247) /Source="Nicolas_S_feature" /locus_tag="new_2989566_2989649_c" /HighExp="LBGstat, T4.0H, LBGtran, T5.0H, C30, dia15, M9-stat, Oxctl, LBGexp, LoTm" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA, SigA, SigA" /TUshortPSig="1, 1, 1, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S1106" promotor_-10 complement(2855236..2855255) /Source="Nicolas_upshift_promotors" /id="U2259" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.675324675324675" /psig=1 /xcortree=2509 /SigmaFactorBS="gcacgtcatcgaataaaaagttgtcgaattgaGGATGacagc gtttgacaaaAAAAGTACAATAGTTTCGGTaaagttattagcaagtctatctgtttga t" /listShort="S1106, accD, accA, S1104, pfkA, pyk, S1103, ytzA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2855247) /Source="Nicolas_upshifts" /id="U2259" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.675324675324675" /psig=1 /xcortree=2509 /SigmaFactorBS="gcacgtcatcgaataaaaagttgtcgaattgaGGATGacagc gtttgacaaaAAAAGTACAATAGTTTCGGTaaagttattagcaagtctatctgtttga t" /listShort="S1106, accD, accA, S1104, pfkA, pyk, S1103, ytzA" /GFF_Attribute="listLong" S_feature complement(2855249..2855401) /Source="Nicolas_S_feature" /locus_tag="new_2989651_2989803_c" /HighExp="Diami, BC, dia15, Sw, dia5, M40t90, H2O2, S2, G/S, Lbstat" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA, SigA" /TUshortPSig="1, 1, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S1107" promotor_-35 complement(2855271..2855275) /Source="Nicolas_upshift_promotors" /id="U2259" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.675324675324675" /psig=1 /xcortree=2509 /SigmaFactorBS="gcacgtcatcgaataaaaagttgtcgaattgaGGATGacagc gtttgacaaaAAAAGTACAATAGTTTCGGTaaagttattagcaagtctatctgtttga t" /listShort="S1106, accD, accA, S1104, pfkA, pyk, S1103, ytzA" /GFF_Attribute="listLong" /label="promotor_-35" S_feature complement(2855403..2855497) /Source="Nicolas_S_feature" /locus_tag="new_2989805_2989899_c" /HighExp="dia15, LBGtran, LBGstat, Diami, LoTm, C90, GM 120, MG 60, M/G, M40t45" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA, SigA" /TUshortPSig="1, 1, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S1108" downshifts complement(2855446) /Source="Nicolas_upshifts" /id="D1499" /incds=0 /nref=52 /ntot=158 /MaxReadThrough="7.72399" /MaxDrop="4.5863" /score="-3.96100458" /energy="-6.8" /TU="U2260,U2262,U2263" /idTUdmin="U2260" /TUdmin="-2178" /isTUend="FALSE" CDS complement(2855498..2856730) /gene="maeB" /locus_tag="BSU_29220" /old_locus_tag="BSU29220" /EC_number="1.1.1.40" /function="16.11: Scavenge (Catabolism)" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:16788182, 22740702, 23136871, 24325460, 25393291" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16788182, 22740702, 23136871, 24325460, 25393291; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="NADP-dependent malic enzyme (conversion of malate into pyruvate, anabolic)" /protein_id="NP_390800.1" /db_xref="EnsemblGenomes-Gn:BSU29220" /db_xref="EnsemblGenomes-Tr:CAB14882" /db_xref="GOA:O34962" /db_xref="InterPro:IPR001891" /db_xref="InterPro:IPR012301" /db_xref="InterPro:IPR012302" /db_xref="InterPro:IPR015884" /db_xref="InterPro:IPR036291" /db_xref="InterPro:IPR037062" /db_xref="SubtiList:BG13922" /db_xref="UniProtKB/Swiss-Prot:O34962" /translation="MSLREEALHLHKVNQGKLESKSKVEVRNAKDLSLAYSPGVAEPC KDIHEDINKVYDYTMKGNMVAVVTDGTAVLGLGNIGPEAALPVMEGKAVLFKSFAGVD AFPIALNTNDVDKIVETVKLLEPTFGGVNLEDIAAPNCFIIEERLKKETNIPVFHDDQ HGTAIVTVAGLVNALKLSGKSMSSIKVVANGAGAAGIAIIKLLHHYGVRDIVMCDSKG AIYEGRPNGMNDVKNEVAKFTNQDRKDGSLKDVIVDADVFIGVSVAGALTKEMVQSMA KDPIIFAMANPNPEIMPEDAREAGASVVGTGRSDFPNQVNNVLAFPGIFRGALDVRAT HINEEMKIAAVEAIASLVSEDELSADYVIPAPFDKRVAPAVAKAVAKAAMETGVARIT VDPEEVAEKTRKLTIIGE*" gene complement(2855498..2856730) /gene="maeB" /locus_tag="BSU_29220" /old_locus_tag="BSU29220" S_feature complement(2856731..2856847) /Source="Nicolas_S_feature" /locus_tag="new_2991133_2991249_c" /HighExp="dia15, Diami, LBGstat, H2O2, LBGtran, dia5, M40t45, Lbtran, LPhT, LoTm" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA, SigA" /TUshortPSig="1, 1, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S1109" promotor_-10 complement(2856835..2856854) /Source="Nicolas_upshift_promotors" /id="U2260" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.98101898101898" /psig=1 /xcortree=1981 /SigmaFactorBS="agctgttgggtcaaaaaaacgtcgttttaaaaCAGTGGTAac gattcgcttttTGTTATACAATTGGAGCAATtatgtgatcctgtttaaatattcagat a" /listShort="S1109, ytsJ, S1108, S1107, S1106, accD, accA" /listLong="S1104, pfkA, pyk, S1103, ytzA" /label="promotor_-10" upshifts complement(2856847) /Source="Nicolas_upshifts" /id="U2260" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.98101898101898" /psig=1 /xcortree=1981 /SigmaFactorBS="agctgttgggtcaaaaaaacgtcgttttaaaaCAGTGGTAac gattcgcttttTGTTATACAATTGGAGCAATtatgtgatcctgtttaaatattcagat a" /listShort="S1109, ytsJ, S1108, S1107, S1106, accD, accA" /listLong="S1104, pfkA, pyk, S1103, ytzA" CDS complement(2856867..2860214) /gene="dnaEC" /locus_tag="BSU_29230" /old_locus_tag="BSU29230" /function="16.9: Replicate" /experiment="publication(s) with functional evidences, PMID:9799485, 9822387, 10354411, 14593098, 20122408, 22333191, 24106089, 29078353" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9799485, 9822387, 10354411, 14593098, 20122408, 22333191, 24106089, 29078353; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="DNA polymerase III (alpha subunit), DnaE3" /protein_id="NP_390801.1" /db_xref="EnsemblGenomes-Gn:BSU29230" /db_xref="EnsemblGenomes-Tr:CAB14883" /db_xref="GOA:O34623" /db_xref="InterPro:IPR003141" /db_xref="InterPro:IPR004013" /db_xref="InterPro:IPR004365" /db_xref="InterPro:IPR004805" /db_xref="InterPro:IPR011708" /db_xref="InterPro:IPR016195" /db_xref="InterPro:IPR029460" /db_xref="SubtiList:BG12583" /db_xref="UniProtKB/Swiss-Prot:O34623" /translation="MSFVHLQVHSGYSLLNSAAAVEELVSEADRLGYASLALTDDHVM YGAIQFYKACKARGINPIIGLTASVFTDDSELEAYPLVLLAKSNTGYQNLLKISSVLQ SKSKGGLKPKWLHSYREGIIAITPGEKGYIETLLEGGLFEQAAQASLEFQSIFGKGAF YFSYQPFKGNQVLSEQILKLSEETGIPVTATGDVHYIRKEDKAAYRCLKAIKAGEKLT DAPAEDLPDLDLKPLEEMQNIYREHPEALQASVEIAEQCRVDVSLGQTRLPSFPTPDG TSADDYLTDICMEGLRSRFGKPDERYLRRLQYELDVIKRMKFSDYFLIVWDFMKHAHE KGIVTGPGRGSAAGSLVAYVLYITDVDPIKHHLLFERFLNPERVSMPDIDIDFPDTRR DEVIQYVQQKYGAMHVAQIITFGTLAAKAALRDVGRVFGVSPKEADQLAKLIPSRPGM TLDEARQQSPQLDKRLRESSLLQQVYSIARKIEGLPRHASTHAAGVVLSEEPLTDVVP LQEGHEGIYLTQYAMDHLEDLGLLKMDFLGLRNLTLIESITSMIEKEENIKIDLSSIS YSDDKTFSLLSKGDTTGIFQLESAGMRSVLKRLKPSGLEDIVAVNALYRPGPMENIPL FIDRKHGRAPVHYPHEDLRSILEDTYGVIVYQEQIMMIASRMAGFSLGEADLLRRAVS KKKKEILDRERSHFVEGCLKKEYSVDTANEVYDLIVKFANYGFNRSHAVAYSMIGCQL AYLKAHYPLYFMCGLLTSVIGNEDKISQYLYEAKGSGIRILPPSVNKSSFPFTVENGS VRYSLRAIKSVGVSAVKDIYKARKEKPFEDLFDFCFRVPSKSVNRKMLEALIFSGAMD EFGQNRATLLASIDVALEHAELFAADDDQMGLFLDESFSIKPKYVETEELPLVDLLAF EKETLGIYFSNHPLSAFRKQLTAQGAVSILQAQRAVKRQLSLGVLLSKIKTIRTKTGQ NMAFLTLSDETGEMEAVVFPEQFRQLSPVLREGALLFTAGKCEVRQDKIQFIMSRAEL LEDMDAEKAPSVYIKIESSQHSQEILAKIKRILLEHKGETGVYLYYERQKQTIKLPES FHINADHQVLYRLKELLGQKNVVLKQW*" gene complement(2856867..2860214) /gene="dnaEC" /locus_tag="BSU_29230" /old_locus_tag="BSU29230" promotor_-35 complement(2856868..2856875) /Source="Nicolas_upshift_promotors" /id="U2260" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.98101898101898" /psig=1 /xcortree=1981 /SigmaFactorBS="agctgttgggtcaaaaaaacgtcgttttaaaaCAGTGGTAac gattcgcttttTGTTATACAATTGGAGCAATtatgtgatcctgtttaaatattcagat a" /listShort="S1109, ytsJ, S1108, S1107, S1106, accD, accA" /listLong="S1104, pfkA, pyk, S1103, ytzA" /label="promotor_-35" promotor_-35 2857879..2857888 /Source="Nicolas_upshift_promotors" /id="U2261" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp="0.995004995004995" /psig="0.995004995004995" /xcortree=1681 /SigmaFactorBS="aacggaaaactgcttttattcactgacggaggaaggataCGA ATCCCGCtcccctttgctTCGTAAAGATATTGAGagattttatcctcattgccaatga c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2857900..2857915 /Source="Nicolas_upshift_promotors" /id="U2261" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp="0.995004995004995" /psig="0.995004995004995" /xcortree=1681 /SigmaFactorBS="aacggaaaactgcttttattcactgacggaggaaggataCGA ATCCCGCtcccctttgctTCGTAAAGATATTGAGagattttatcctcattgccaatga c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2857900 /Source="Nicolas_upshifts" /id="U2261" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp="0.995004995004995" /psig="0.995004995004995" /xcortree=1681 /SigmaFactorBS="aacggaaaactgcttttattcactgacggaggaaggataCGA ATCCCGCtcccctttgctTCGTAAAGATATTGAGagattttatcctcattgccaatga c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 complement(2858088..2858107) /Source="Nicolas_upshift_promotors" /id="U2262" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.973026973026973" /psig=1 /xcortree=2017 /SigmaFactorBS="aaaagaaaaaagaaatcctggacagagagcgaagccattTTG TTGAAgggtgcttaaaaaAGGAGTATTCTGTAGACACTgcaaatgaggtctacgattt a" /listShort="S1109, ytsJ, S1108, S1107, S1106, accD, accA, S1104, pfkA, pyk, S1103, ytzA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2858107) /Source="Nicolas_upshifts" /id="U2262" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.973026973026973" /psig=1 /xcortree=2017 /SigmaFactorBS="aaaagaaaaaagaaatcctggacagagagcgaagccattTTG TTGAAgggtgcttaaaaaAGGAGTATTCTGTAGACACTgcaaatgaggtctacgattt a" /listShort="S1109, ytsJ, S1108, S1107, S1106, accD, accA, S1104, pfkA, pyk, S1103, ytzA" /GFF_Attribute="listLong" promotor_-35 complement(2858121..2858128) /Source="Nicolas_upshift_promotors" /id="U2262" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.973026973026973" /psig=1 /xcortree=2017 /SigmaFactorBS="aaaagaaaaaagaaatcctggacagagagcgaagccattTTG TTGAAgggtgcttaaaaaAGGAGTATTCTGTAGACACTgcaaatgaggtctacgattt a" /listShort="S1109, ytsJ, S1108, S1107, S1106, accD, accA, S1104, pfkA, pyk, S1103, ytzA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(2860245..2860264) /Source="Nicolas_upshift_promotors" /id="U2263" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.98901098901099" /psig=1 /xcortree=2091 /SigmaFactorBS="agctttcaggacaagtatgatgatgagtcaaaaaagaaCATT TGTTtcttttggaaaccGGCCTTATAATGAAGGAAGAaatggatcgtaatgagaaaga g" /listShort="dnaE, S1109, ytsJ, S1108, S1107, S1106, accD, accA" /listLong="S1104, pfkA, pyk, S1103, ytzA" /label="promotor_-10" upshifts complement(2860263) /Source="Nicolas_upshifts" /id="U2263" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.98901098901099" /psig=1 /xcortree=2091 /SigmaFactorBS="agctttcaggacaagtatgatgatgagtcaaaaaagaaCATT TGTTtcttttggaaaccGGCCTTATAATGAAGGAAGAaatggatcgtaatgagaaaga g" /listShort="dnaE, S1109, ytsJ, S1108, S1107, S1106, accD, accA" /listLong="S1104, pfkA, pyk, S1103, ytzA" promotor_-35 complement(2860278..2860285) /Source="Nicolas_upshift_promotors" /id="U2263" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.98901098901099" /psig=1 /xcortree=2091 /SigmaFactorBS="agctttcaggacaagtatgatgatgagtcaaaaaagaaCATT TGTTtcttttggaaaccGGCCTTATAATGAAGGAAGAaatggatcgtaatgagaaaga g" /listShort="dnaE, S1109, ytsJ, S1108, S1107, S1106, accD, accA" /listLong="S1104, pfkA, pyk, S1103, ytzA" /label="promotor_-35" promotor_-35 2860303..2860308 /Source="Nicolas_upshift_promotors" /id="U2264" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp="0.994005994005994" /psig="0.994005994005994" /xcortree=988 /SigmaFactorBS="aggccggtttccaaaagaaacaaatgttcttttttgactcat cATCATActtgtcctgaaagctCAATATGATATAAAAGGTGaggtgataaagatggat c" /listShort="ytrH, ytrI" /listLong="ytzJ, S1110, S1111, S1112, ytpI, S1114" /label="promotor_-35" upshifts 2860320 /Source="Nicolas_upshifts" /id="U2264" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp="0.994005994005994" /psig="0.994005994005994" /xcortree=988 /SigmaFactorBS="aggccggtttccaaaagaaacaaatgttcttttttgactcat cATCATActtgtcctgaaagctCAATATGATATAAAAGGTGaggtgataaagatggat c" /listShort="ytrH, ytrI" /listLong="ytzJ, S1110, S1111, S1112, ytpI, S1114" promotor_-10 2860324..2860342 /Source="Nicolas_upshift_promotors" /id="U2264" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp="0.994005994005994" /psig="0.994005994005994" /xcortree=988 /SigmaFactorBS="aggccggtttccaaaagaaacaaatgttcttttttgactcat cATCATActtgtcctgaaagctCAATATGATATAAAAGGTGaggtgataaagatggat c" /listShort="ytrH, ytrI" /listLong="ytzJ, S1110, S1111, S1112, ytpI, S1114" /label="promotor_-10" CDS 2860354..2860695 /gene="ytrH" /locus_tag="BSU_29239" /old_locus_tag="BSU29239" /function="16.13: Shape" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:12662922, 15547282, 26735940" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12662922, 15547282, 26735940; Product type ph: phenotype" /codon_start=1 /transl_table=11 /product="membrane protein involved in a sporulation process" /protein_id="YP_003097771.1" /db_xref="EnsemblGenomes-Gn:BSU29239" /db_xref="EnsemblGenomes-Tr:CAX52677" /db_xref="GOA:C0H3P8" /db_xref="InterPro:IPR025689" /db_xref="UniProtKB/Swiss-Prot:C0H3P8" /translation="MDQEAGFMVNFINSYFIALGVLIGGALIGGLGAYLAGEPPLTAI TKLANRLKIWALVAAIGGTFDAVYSFERGILEGNTRDIFKQLLLIISAMGGAQSGWLI ISWLTQEHLSS*" gene 2860354..2860695 /gene="ytrH" /locus_tag="BSU_29239" /old_locus_tag="BSU29239" CDS 2860692..2861195 /gene="ytrI" /locus_tag="BSU_29240" /old_locus_tag="BSU29240" /function="16.13: Shape" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:12662922, 15547282, 26735940" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12662922, 15547282, 26735940; Product type ph: phenotype" /codon_start=1 /transl_table=11 /product="protein involved in sporulation" /protein_id="NP_390802.3" /db_xref="EnsemblGenomes-Gn:BSU29240" /db_xref="EnsemblGenomes-Tr:CAB14884" /db_xref="GOA:O34460" /db_xref="SubtiList:BG13917" /db_xref="UniProtKB/Swiss-Prot:O34460" /translation="MRVPQHYKKPGWQRFFAGMMCGAVISWFFFLFTYGTFQEEQVSL IEKQKEHVKDLNNQISIYQEDLHKLNEDNKRKLLIQSVSVKLLNGDKYKISQPDKTKF EEHVKDDISEVITKDIESVYQTKDLLKRTIENKVYMINEKKYEATVRELIIYTRLTVE LEISFAT*" gene 2860692..2861195 /gene="ytrI" /locus_tag="BSU_29240" /old_locus_tag="BSU29240" promotor_-35 2861228..2861231 /Source="Nicolas_upshift_promotors" /id="U2265" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.487512487512487" /psig="0.973026973026973" /xcortree=529 /SigmaFactorBS="cgccacataattatggattttttttaaattctccaaacttct GTCGctttttcccattctTTTTTATAAACTATATGTGAggcttaatggcgaaaggaag g" /listShort="ytzJ, S1110, S1111, S1112, ytpI, S1114" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2861246..2861265 /Source="Nicolas_upshift_promotors" /id="U2265" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.487512487512487" /psig="0.973026973026973" /xcortree=529 /SigmaFactorBS="cgccacataattatggattttttttaaattctccaaacttct GTCGctttttcccattctTTTTTATAAACTATATGTGAggcttaatggcgaaaggaag g" /listShort="ytzJ, S1110, S1111, S1112, ytpI, S1114" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2861246 /Source="Nicolas_upshifts" /id="U2265" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.487512487512487" /psig="0.973026973026973" /xcortree=529 /SigmaFactorBS="cgccacataattatggattttttttaaattctccaaacttct GTCGctttttcccattctTTTTTATAAACTATATGTGAggcttaatggcgaaaggaag g" /listShort="ytzJ, S1110, S1111, S1112, ytpI, S1114" /GFF_Attribute="listLong" CDS 2861297..2861488 /gene="ytzJ" /locus_tag="BSU_29249" /old_locus_tag="BSU29249" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="putative sporulation-related conserved protein" /protein_id="YP_003097772.1" /db_xref="EnsemblGenomes-Gn:BSU29249" /db_xref="EnsemblGenomes-Tr:CAX52678" /db_xref="UniProtKB/Swiss-Prot:C0H3P9" /translation="MEVYSDRQLAKDQAARLRQGFSAYAETNSLASLIKKELQSHNLQ VYEDLTDFGCWFIPVTDEH*" gene 2861297..2861488 /gene="ytzJ" /locus_tag="BSU_29249" /old_locus_tag="BSU29249" downshifts complement(2861298) /Source="Nicolas_upshifts" /id="D1500" /incds=0 /nref=1 /ntot=5 /MaxReadThrough="2.45109" /MaxDrop="3.19151" /score="-1.37123732" /energy="-6.5" /TU="NA" /idTUdmin="U2268" /TUdmin=220 /isTUend="FALSE" downshifts 2861464 /Source="Nicolas_upshifts" /id="D1501" /incds=0 /nref=15 /ntot=107 /MaxReadThrough="6.88261" /MaxDrop="6.74738" /score="-8.58003897" /energy="-4" /TU="U2265" /idTUdmin="U2264" /TUdmin=242 /isTUend="FALSE" CDS complement(2861506..2862447) /gene="nrnA" /locus_tag="BSU_29250" /old_locus_tag="BSU29250" /EC_number="3.1.3.7" /EC_number="3.1.-.-" /function="16.6: Maintain" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:17586819, 19553197, 22102036, 26735940, 28894100" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 17586819, 19553197, 22102036, 26735940, 28894100; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="nanoRNase (oligoribonuclease) (3'->5'short substrates, 5'->3' long substrates), 3',5'-bisphosphate nucleotidase" /protein_id="NP_390803.1" /db_xref="EnsemblGenomes-Gn:BSU29250" /db_xref="EnsemblGenomes-Tr:CAB14885" /db_xref="GOA:O34600" /db_xref="InterPro:IPR001667" /db_xref="InterPro:IPR003156" /db_xref="PDB:5IPP" /db_xref="PDB:5IUF" /db_xref="PDB:5IZO" /db_xref="PDB:5J21" /db_xref="SubtiList:BG13910" /db_xref="UniProtKB/Swiss-Prot:O34600" /translation="MKTELIRTISLYDTIILHRHVRPDPDAYGSQCGLTEILRETYPE KNIFAVGTPEPSLSFLYSLDEVDNETYEGALVIVCDTANQERIDDQRYPSGAKLMKID HHPNEDPYGDLLWVDTSASSVSEMIYELYLEGKEHGWKLNTKAAELIYAGIVGDTGRF LFPNTTEKTLKYAGELIQYPFSSSELFNQLYETKLNVVKLNGFIFQNVSLSENGAASV FIKKDTLEKFGTTASEASQLVGTLGNISGIRAWVFFVEEDDQIRVRFRSKGPVINGLA RKYNGGGHPLASGASIYSWDEADRILADLETLCKEHE*" gene complement(2861506..2862447) /gene="nrnA" /locus_tag="BSU_29250" /old_locus_tag="BSU29250" S_feature 2861509..2861880 /Source="Nicolas_S_feature" /locus_tag="new_2995911_2996282" /HighExp="Lbstat, S2, M0t90, M40t90, nit, ferm, S3, BT, M9-stat, S0" /AntisenseName="nrnA" /AntisenseCor="-0.77648424268923499" /AntisenseRegPval="-54.8" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.973" /TUlongSig="SigEF" /TUlongPSig="0.994" /label="S1110" downshifts complement(2861541) /Source="Nicolas_upshifts" /id="D1502" /incds=0 /nref=25 /ntot=163 /MaxReadThrough="3.12169" /MaxDrop="3.09205" /score="22.5196409" /energy="-7.9" /TU="U2268" /idTUdmin="U2269" /TUdmin="-1" /isTUend="TRUE" promotor_-35 2861849..2861858 /Source="Nicolas_upshift_promotors" /id="U2266" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1354 /SigmaFactorBS="gacacattttgaaagataaagccgttaAGCTTCACCAcattc agttttgtTTCATACAATTGATTAAATAactctgaggaagagaatggatactgaatga g" /listShort="S1111, S1112, ytpI, S1114" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2861872..2861891 /Source="Nicolas_upshift_promotors" /id="U2266" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1354 /SigmaFactorBS="gacacattttgaaagataaagccgttaAGCTTCACCAcattc agttttgtTTCATACAATTGATTAAATAactctgaggaagagaatggatactgaatga g" /listShort="S1111, S1112, ytpI, S1114" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 2861882..2862276 /Source="Nicolas_S_feature" /locus_tag="new_2996284_2996678" /HighExp="Lbstat, S2, S7, S8, S6, nit, ferm, M0t90, BT, M40t90" /AntisenseName="nrnA" /AntisenseCor="-0.85531073541330804" /AntisenseRegPval="-77.5" /CDS_PredictionProba="NA" /TUshortSig="SigK, SigA" /TUshortPSig="1, 0.973" /TUlongSig="SigEF" /TUlongPSig="0.994" /label="S1111" upshifts 2861882 /Source="Nicolas_upshifts" /id="U2266" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1354 /SigmaFactorBS="gacacattttgaaagataaagccgttaAGCTTCACCAcattc agttttgtTTCATACAATTGATTAAATAactctgaggaagagaatggatactgaatga g" /listShort="S1111, S1112, ytpI, S1114" /GFF_Attribute="listLong" promotor_-35 2862238..2862244 /Source="Nicolas_upshift_promotors" /id="U2267" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.698301698301698" /psig="0.698301698301698" /xcortree=742 /SigmaFactorBS="atgacaagtgcgccttcataTGTTTCAttgtccacctcatca AGGGAATATAAGAAAGAGAGggacggttcaggcgtgccgaccgcaaaaatattttttt c" /listShort="S1112, ytpI, S1114" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2862260..2862279 /Source="Nicolas_upshift_promotors" /id="U2267" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.698301698301698" /psig="0.698301698301698" /xcortree=742 /SigmaFactorBS="atgacaagtgcgccttcataTGTTTCAttgtccacctcatca AGGGAATATAAGAAAGAGAGggacggttcaggcgtgccgaccgcaaaaatattttttt c" /listShort="S1112, ytpI, S1114" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 2862278..2862577 /Source="Nicolas_S_feature" /locus_tag="new_2996680_2996979" /HighExp="Lbstat, S8, S7, S6, S2, Etha, nit, ferm, BT, M0t90" /AntisenseName="nrnA" /AntisenseCor="-0.84034645112995598" /AntisenseRegPval="-72.2" /CDS_PredictionProba="NA" /TUshortSig="SigB, SigK, SigA" /TUshortPSig="0.698, 1, 0.973" /TUlongSig="SigEF" /TUlongPSig="0.994" /label="S1112" upshifts 2862278 /Source="Nicolas_upshifts" /id="U2267" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.698301698301698" /psig="0.698301698301698" /xcortree=742 /SigmaFactorBS="atgacaagtgcgccttcataTGTTTCAttgtccacctcatca AGGGAATATAAGAAAGAGAGggacggttcaggcgtgccgaccgcaaaaatattttttt c" /listShort="S1112, ytpI, S1114" /GFF_Attribute="listLong" promotor_-10 complement(2862466..2862485) /Source="Nicolas_upshift_promotors" /id="U2268" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.515484515484515" /psig="0.995004995004995" /xcortree=2384 /SigmaFactorBS="attttatacaaaaacgggcttggttttgacgttatttttCTT TtccgtcggcagagaATGTGATTTAATGAATAAAAacaataaaggagtatcaaatgaa a" /listShort="nrnA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2862482) /Source="Nicolas_upshifts" /id="U2268" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.515484515484515" /psig="0.995004995004995" /xcortree=2384 /SigmaFactorBS="attttatacaaaaacgggcttggttttgacgttatttttCTT TtccgtcggcagagaATGTGATTTAATGAATAAAAacaataaaggagtatcaaatgaa a" /listShort="nrnA" /GFF_Attribute="listLong" S_feature complement(2862484..2862898) /Source="Nicolas_S_feature" /locus_tag="new_2996886_2997300_c" /HighExp="LBGtran, HiTm, G180, G135, G150, Lbtran, LBGexp, Mt0, Paraq, dia0" /AntisenseName="ytpI" /AntisenseCor="-0.70134306018551296" /AntisenseRegPval="-40.4" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.993" /TUlongSig="NA" /TUlongPSig="NA" /label="S1113" promotor_-35 complement(2862500..2862503) /Source="Nicolas_upshift_promotors" /id="U2268" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.515484515484515" /psig="0.995004995004995" /xcortree=2384 /SigmaFactorBS="attttatacaaaaacgggcttggttttgacgttatttttCTT TtccgtcggcagagaATGTGATTTAATGAATAAAAacaataaaggagtatcaaatgaa a" /listShort="nrnA" /GFF_Attribute="listLong" /label="promotor_-35" CDS 2862578..2862880 /gene="ytpI" /locus_tag="BSU_29260" /old_locus_tag="BSU29260" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_390804.1" /db_xref="EnsemblGenomes-Gn:BSU29260" /db_xref="EnsemblGenomes-Tr:CAB14886" /db_xref="GOA:O34922" /db_xref="InterPro:IPR025618" /db_xref="SubtiList:BG13902" /db_xref="UniProtKB/Swiss-Prot:O34922" /translation="MLVLVFLIGLSACFYVYYKVKGVRAKPSLAKEICSAKSSMALGS LVLFYGLNQMILFHSVLTLVIGGIFIVIGAGSAWAGYKAFRHYNPLHAKEAERDHA*" gene 2862578..2862880 /gene="ytpI" /locus_tag="BSU_29260" /old_locus_tag="BSU29260" S_feature 2862881..2864676 /Source="Nicolas_S_feature" /locus_tag="new_2997283_2999078" /HighExp="S8, S6, S7, Lbstat, B36, nit, ferm, T1.0H, C30, S5" /AntisenseName="ytoI" /AntisenseCor="-0.55304378374907204" /AntisenseRegPval="-22.2" /CDS_PredictionProba="0.89152299999999995" /TUshortSig="SigB, SigK, SigA" /TUshortPSig="0.698, 1, 0.973" /TUlongSig="SigEF" /TUlongPSig="0.994" /label="S1114" CDS complement(2862899..2864218) /gene="ytoI" /locus_tag="BSU_29270" /old_locus_tag="BSU29270" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 26296725" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_390805.1" /db_xref="EnsemblGenomes-Gn:BSU29270" /db_xref="EnsemblGenomes-Tr:CAB14887" /db_xref="GOA:O34921" /db_xref="InterPro:IPR000524" /db_xref="InterPro:IPR000644" /db_xref="InterPro:IPR006683" /db_xref="InterPro:IPR010766" /db_xref="InterPro:IPR028979" /db_xref="InterPro:IPR029069" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG13897" /db_xref="UniProtKB/Swiss-Prot:O34921" /translation="MATKHEQILTYIDSLPVGEKISVRRIAKEMKVSEGTAYRAIKEA ENKGFVSTIERVGTIRIEQKKKENIEKLTYAEVVNVIDGQVLGGRAGLHKTLNKFVIG AMELDAMMRYTAAGNLLIVGNRINAHRQALEAGAAVLVTGGFNTDDSIVQLADELELP ILSTSYDTFTVAAMINRAIYDQLIKKEIVLVEDILTPADRTVYLSPKDKLEKWYEKNF ETGHGRFPVVDDQMKIHGILTSKDIAGHDRNASIEKVMTKNPVTVIGKTSVASAAQMM VWEGIEVLPVTDGHQKLIGMISRQDVLKALQMIQKQPQVGEKLDDIVSRGFKDEGDDK EDQTVYEYEVTPQMTNQLGTISYGVFTTILTQAANRFLRSKKRGELVIESITIFFLKP VQMESVIEVKPRILEAGRKFGKMEVEVHSQGHIVSKAMLMVQLMERS*" gene complement(2862899..2864218) /gene="ytoI" /locus_tag="BSU_29270" /old_locus_tag="BSU29270" promotor_-10 complement(2864244..2864263) /Source="Nicolas_upshift_promotors" /id="U2269" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.491508491508492" /psig="0.993006993006993" /xcortree=2263 /SigmaFactorBS="ctgtaagaagccggtcgggcttcttttttattttccagcctc ATTGCGtataaatcctttgaAACCTTATAATAAAAACAAGaagactgtccttagaggt g" /listShort="ytoI, S1113, nrnA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2864265) /Source="Nicolas_upshifts" /id="U2269" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.491508491508492" /psig="0.993006993006993" /xcortree=2263 /SigmaFactorBS="ctgtaagaagccggtcgggcttcttttttattttccagcctc ATTGCGtataaatcctttgaAACCTTATAATAAAAACAAGaagactgtccttagaggt g" /listShort="ytoI, S1113, nrnA" /GFF_Attribute="listLong" promotor_-35 complement(2864278..2864283) /Source="Nicolas_upshift_promotors" /id="U2269" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.491508491508492" /psig="0.993006993006993" /xcortree=2263 /SigmaFactorBS="ctgtaagaagccggtcgggcttcttttttattttccagcctc ATTGCGtataaatcctttgaAACCTTATAATAAAAACAAGaagactgtccttagaggt g" /listShort="ytoI, S1113, nrnA" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2864394..2865296) /gene="ytnM" /locus_tag="BSU_29280" /old_locus_tag="BSU29280" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406, 23944997; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative transporter" /protein_id="NP_390806.1" /db_xref="EnsemblGenomes-Gn:BSU29280" /db_xref="EnsemblGenomes-Tr:CAB14888" /db_xref="GOA:O34430" /db_xref="InterPro:IPR002781" /db_xref="SubtiList:BG13894" /db_xref="UniProtKB/Swiss-Prot:O34430" /translation="MKKLIVFAFIGLLSQLIDGSLGMAYGVTSTSLLLAFGITPAVAS ASVHLAEVVTTAASGVSHIKFGNVDKQTVYQLVIPGSIGAFLGAAFLSQLPGDVAKPY ISLFLLLLGGYVLIRFLFQYKPALEKKHVPLNRKQSIPLGVIAGFADATGGGGWGPVT TPILLSRKGLSPRKVVGTVDTSEFAIAVSATAGFLISLGWEDVNWLWVFSLMAGGIIA APIAAWLVQKFHPQLMGVLVGGFIILVNARTLINEWIANTAVHPLIYTAIGAIWLSAV LFVLSKIGNRNIVKTAVDVHLKEK*" gene complement(2864394..2865296) /gene="ytnM" /locus_tag="BSU_29280" /old_locus_tag="BSU29280" CDS complement(2865315..2866565) /gene="sndA" /locus_tag="BSU_29290" /old_locus_tag="BSU29290" /EC_number="3.-.-.-" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:10588044, 10939241, 11423008, 16109943, 23944997" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10588044, 10939241, 11423008, 16109943, 23944997; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="S-alkyl-N-acetyl-metabolite deacetylase" /protein_id="NP_390807.1" /db_xref="EnsemblGenomes-Gn:BSU29290" /db_xref="EnsemblGenomes-Tr:CAB14889" /db_xref="GOA:O34980" /db_xref="InterPro:IPR002933" /db_xref="InterPro:IPR011650" /db_xref="InterPro:IPR017439" /db_xref="InterPro:IPR033846" /db_xref="InterPro:IPR036264" /db_xref="SubtiList:BG12596" /db_xref="UniProtKB/Swiss-Prot:O34980" /translation="MSLDYWRNIEGSYPYQTTGNDILTLKEESNPVNLSTLEKQLIGI RRHLHQYPELSKEEFETTAFIKKCLKEKGIQIRPTALKTGVFADIAGESEGPAIALRA DIDALPIEEKTGLPYASKHKGIMHACGHDFHTAALLGAAFLLKENQDSLKGKIRLLFQ PAEEAGAGATKVIEDGQLDGIDAVIGLHNKPDIAVGTVGLKTGPLMAAVDRFKVEIEG KGAHAALPHNGFDPIIGASQLIVALQTIVSRNVNPLQSAILTVGKINGGSTWNVIPDT VVIEGTVRTFDSEVRNQVKQRFFAVTEQISAAFSLKANVKWHSGPPPLCNDEAITGLV RDAAHKAKLQVIDPAPSTAGEDFAYYLEHIPGSFAFFGTDGDHDWHHPAFTIDETAII KASYFLYESAKRLLDSNEESKISD*" gene complement(2865315..2866565) /gene="sndA" /locus_tag="BSU_29290" /old_locus_tag="BSU29290" CDS complement(2866583..2867275) /gene="ribR" /locus_tag="BSU_29300" /old_locus_tag="BSU29300" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:10939241, 11423008, 15668000, 16109943, 17590224, 23944997, 26494285" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10939241, 11423008, 15668000, 16109943, 17590224, 23944997, 26494285; Product type r: regulator" /codon_start=1 /transl_table=11 /product="FMN-riboswitch-binding activator of rib genes" /protein_id="NP_390808.1" /db_xref="EnsemblGenomes-Gn:BSU29300" /db_xref="EnsemblGenomes-Tr:CAB14890" /db_xref="GOA:P94465" /db_xref="InterPro:IPR015865" /db_xref="InterPro:IPR023465" /db_xref="InterPro:IPR023468" /db_xref="SubtiList:BG11969" /db_xref="UniProtKB/Swiss-Prot:P94465" /translation="MTIIAGTVVKGKQLGRKLGFPTANVDAKIHGLRNGVYGVLATVN HQFHLGVMNIGVKPTVGSNLEKTLEIFLFDFHRDIYGEKIECSILFKIREERRFDSLE SLTKQIKKDISCVAKRFELIGIMAPNKKESLLSHQELNLPDLCFYKKCNNLYGVNRGV YNVIDNWFFEYGITQVAYRRIYILSFLSFLKEDNPKVSSKYIRFGAGGLADKLNRFIS SYVEESEENILG*" gene complement(2866583..2867275) /gene="ribR" /locus_tag="BSU_29300" /old_locus_tag="BSU29300" CDS complement(2867322..2868650) /gene="cmoJ" /locus_tag="BSU_29310" /old_locus_tag="BSU29310" /EC_number="1.14.-.-" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:10939241, 11423008, 16109943, 23944997" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10939241, 11423008, 16109943, 23944997; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="monooxygenase (S-alkyl substrates)" /protein_id="NP_390809.1" /db_xref="EnsemblGenomes-Gn:BSU29310" /db_xref="EnsemblGenomes-Tr:CAB14891" /db_xref="GOA:O34974" /db_xref="InterPro:IPR011251" /db_xref="InterPro:IPR016215" /db_xref="InterPro:IPR036661" /db_xref="PDB:1TVL" /db_xref="PDB:1YW1" /db_xref="SubtiList:BG13893" /db_xref="UniProtKB/Swiss-Prot:O34974" /translation="MTRADFIQFGAMIHGVGGTTDGWRHPDVDPSASTNIEFYMKKAQ TAEKGLFSFIFIADGLFISEKSIPHFLNRFEPITILSALASVTKNIGLVGTFSTSFTE PFTISRQLMSLDHISGGRAGWNLVTSPQEGAARNHSKSNLPEHTERYEIAQEHLDVVR GLWNSWEHDAFIHNKKTGQFFDQAKLHRLNHKGKYFQVEGPLNIGRSKQGEPVVFQAG SSETGRQFAAKNADAIFTHSNSLEETKAFYADVKSRAADEGRDPSSVRIFPGISPIVA DTEEEAEKKYREFAELIPIENAVTYLARFFDDYDLSVYPLDEPFPDIGDVGKNAFQST TDRIKREAKARNLTLREVAQEMAFPRTLFIGTPERVASLIETWFNAEAADGFIVGSDI PGTLDAFVEKVIPILQERGLYRQDYRGGTLRENLGLGIPQHQSVLHSSHH*" gene complement(2867322..2868650) /gene="cmoJ" /locus_tag="BSU_29310" /old_locus_tag="BSU29310" CDS complement(2868647..2868928) /gene="cmoI" /locus_tag="BSU_29320" /old_locus_tag="BSU29320" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:10939241, 11423008, 16109943, 23944997" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10939241, 11423008, 16109943, 23944997; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="redoxin" /protein_id="NP_390810.1" /db_xref="EnsemblGenomes-Gn:BSU29320" /db_xref="EnsemblGenomes-Tr:CAB14892" /db_xref="GOA:O34639" /db_xref="InterPro:IPR002109" /db_xref="InterPro:IPR036249" /db_xref="SubtiList:BG13892" /db_xref="UniProtKB/Swiss-Prot:O34639" /translation="MSDVVNIVVWSKKGCSYCEEVKNYLNEKGFPFQNIDVSEKEKLR DILQVKYGVRHVPVVEIGRGNQYQGITEIGIEHLDLALANHAQIKEAKR*" gene complement(2868647..2868928) /gene="cmoI" /locus_tag="BSU_29320" /old_locus_tag="BSU29320" CDS complement(2868943..2869947) /gene="cmoO" /locus_tag="BSU_29330" /old_locus_tag="BSU29330" /EC_number="1.14.-.-" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:9836433, 10939241, 11423008, 16109943, 23944997" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9836433, 10939241, 11423008, 16109943, 23944997; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="monooxygenase (S-alkyl substrates)" /protein_id="NP_390811.1" /db_xref="EnsemblGenomes-Gn:BSU29330" /db_xref="EnsemblGenomes-Tr:CAB14893" /db_xref="GOA:O34846" /db_xref="InterPro:IPR011251" /db_xref="InterPro:IPR019949" /db_xref="InterPro:IPR036661" /db_xref="SubtiList:BG13888" /db_xref="UniProtKB/Swiss-Prot:O34846" /translation="MIRLSILDQSLIGEGETAADTLQHTVKLAQMAEECGYHRFWVAE HHNNDEIAGSAPEVLLGYLAASTRKIRLASGGVMLQHYSSYKVAEQFHLLSALAPGRI DLGVGKAPGGFQLSTDALQAEYKKPVRQFDEKLEELTHFVRDDFPDTHRYAALRPRPQ VDRKPGIFLLGGSTESAISAAKLGISFVFAYFINGEEEVLKEARRAFDAHLPPGSEAE FHLAPAVFAAHTKEEAEKHIVSRESIKVVLKDGRKVNVGSREQAEAYLENVTEPYDII VQKTGIIAGTKEEVAEELTRLSGTYKINDFVIFTPIKNAVEKQLSYQLLSDAVLAAKR *" gene complement(2868943..2869947) /gene="cmoO" /locus_tag="BSU_29330" /old_locus_tag="BSU29330" CDS complement(2869944..2870723) /gene="tcyN" /locus_tag="BSU_29340" /old_locus_tag="BSU29340" /experiment="publication(s) with functional evidences, PMID:10939241, 11423008, 15262924, 23944997" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10939241, 11423008, 15262924, 23944997; Product type t: transporter" /codon_start=1 /transl_table=11 /product="sulfur-containing amino-acid ABC transporter (ATP-binding protein)" /protein_id="NP_390812.1" /db_xref="EnsemblGenomes-Gn:BSU29340" /db_xref="EnsemblGenomes-Tr:CAB14894" /db_xref="GOA:O34900" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR017871" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR030679" /db_xref="SubtiList:BG12604" /db_xref="UniProtKB/Swiss-Prot:O34900" /translation="MIEIKNIHKQFGIHHVLKGINLTVRKGEVVTIIGPSGSGKTTFL RCLNLLERPDEGIISIHDKVINCRFPSKKEVHWLRKQTAMVFQQYHLFAHKTVIENVM EGLTIARKMRKQDAYAVAENELRKVGLQDKLNAYPSQLSGGQKQRVGIARALAIHPDV LLFDEPTAALDPELVGEVLEVMLEIVKTGATMIVVTHEMEFARRVSDQVVFMDEGVIV EQGTPEEVFRHTKKDRTRQFLRRVSPEYLFEPKEHIKEPVI*" gene complement(2869944..2870723) /gene="tcyN" /locus_tag="BSU_29340" /old_locus_tag="BSU29340" CDS complement(2870720..2871427) /gene="tcyM" /locus_tag="BSU_29350" /old_locus_tag="BSU29350" /experiment="publication(s) with functional evidences, PMID:10939241, 11423008, 15262924, 15849754, 16850406, 23944997" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10939241, 11423008, 15262924, 15849754, 16850406, 23944997; Product type t : transporter" /codon_start=1 /transl_table=11 /product="sulfur-containing amino acid ABC transporter (permease)" /protein_id="NP_390813.1" /db_xref="EnsemblGenomes-Gn:BSU29350" /db_xref="EnsemblGenomes-Tr:CAB14895" /db_xref="GOA:O34931" /db_xref="InterPro:IPR000515" /db_xref="InterPro:IPR010065" /db_xref="InterPro:IPR035906" /db_xref="SubtiList:BG13887" /db_xref="UniProtKB/Swiss-Prot:O34931" /translation="MQFDFPFIVSAMKEMVKTIPLTLMMAVLPIVFGFLVALGNIIVR IFRIKGLVACSRFYVSFFRSTPAILHIMLIYLGIPPVADQVSSFFHLGWSANEIPVSM FVIMALSLTAGAYLTEIIRSGILAMDTGQVEAAYSIGLTYSQTFRRVILPQALKVSIP NFTNLGIGFLHTTSIAAIVAVPEITGTATIVASDNYAFLEAFIGAAIIYWVLTLILES ANGVLERKAARFQGGTL*" gene complement(2870720..2871427) /gene="tcyM" /locus_tag="BSU_29350" /old_locus_tag="BSU29350" CDS complement(2871457..2872176) /gene="tcyL" /locus_tag="BSU_29360" /old_locus_tag="BSU29360" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:10939241, 11423008, 15262924, 15849754, 16850406, 23944997" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10939241, 11423008, 15262924, 15849754, 16850406, 23944997; Product type t : transporter" /codon_start=1 /transl_table=11 /product="sulfur-containing amino acid ABC transporter (permease)" /protein_id="NP_390814.1" /db_xref="EnsemblGenomes-Gn:BSU29360" /db_xref="EnsemblGenomes-Tr:CAB14896" /db_xref="GOA:O34315" /db_xref="InterPro:IPR000515" /db_xref="InterPro:IPR010065" /db_xref="InterPro:IPR035906" /db_xref="SubtiList:BG13886" /db_xref="UniProtKB/Swiss-Prot:O34315" /translation="MEKAFDMNMIGDFVPTLTAYLPVTLYILTLSLLFGFVLGLFLAL PRIYNIPIVNQLAKVYISFFRGTPIMVQLFIVFYGIPALTGLIGIDTSKMDPFYAAVA TYALSNAAAAAEIIRAGVGSVDKGQTEAAYSIGLSGSQAFRRIVLPQALVQAFPNMGN MVISSLKDTSLAFSIGVMDMSGRGQTLITSSNHSLEVYIALSIVYYAVAVLFEWFFRV AEKRIKKNQTRIVTVFDMNIH*" gene complement(2871457..2872176) /gene="tcyL" /locus_tag="BSU_29360" /old_locus_tag="BSU29360" promotor_-35 2872002..2872009 /Source="Nicolas_upshift_promotors" /id="U2270" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.473526473526474" /psig="0.632367632367632" /xcortree=1226 /SigmaFactorBS="caccatgataggcgttcccctgaaaaacgagatatacaCTTT TGCCaattgatttacaatTGGAATATTATAGATGCGGGgcagtgccagaaagagtcct a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2872024..2872043 /Source="Nicolas_upshift_promotors" /id="U2270" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.473526473526474" /psig="0.632367632367632" /xcortree=1226 /SigmaFactorBS="caccatgataggcgttcccctgaaaaacgagatatacaCTTT TGCCaattgatttacaatTGGAATATTATAGATGCGGGgcagtgccagaaagagtcct a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2872024 /Source="Nicolas_upshifts" /id="U2270" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.473526473526474" /psig="0.632367632367632" /xcortree=1226 /SigmaFactorBS="caccatgataggcgttcccctgaaaaacgagatatacaCTTT TGCCaattgatttacaatTGGAATATTATAGATGCGGGgcagtgccagaaagagtcct a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" CDS complement(2872198..2873010) /gene="tcyK" /locus_tag="BSU_29370" /old_locus_tag="BSU29370" /experiment="publication(s) with functional evidences, PMID:10939241, 11423008, 15262924, 22720735, 23944997" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10939241, 11423008, 15262924, 22720735, 23944997; Product type t : transporter" /codon_start=1 /transl_table=11 /product="sulfur-containing amino acid ABC transporter binding lipoprotein" /protein_id="NP_390815.1" /db_xref="EnsemblGenomes-Gn:BSU29370" /db_xref="EnsemblGenomes-Tr:CAB14897" /db_xref="GOA:O34852" /db_xref="InterPro:IPR001638" /db_xref="PDB:2O1M" /db_xref="SubtiList:BG13885" /db_xref="UniProtKB/Swiss-Prot:O34852" /translation="MKTKTAFMAILFSLITVLSACGAGSQTTGAGQKKVQTITVGTGT QFPNICFIDEKGDLTGYDVELIKELDKRLPHYKFTFKTMEFSNLLVSLGQHKVDIVAH QMEKSKEREKKFLFNKVAYNHFPLKITVLQNNDTIRGIEDLKGKRVITSATSNGALVL KKWNEDNGRPFEIAYEGQGANETANQLKSGRADATISTPFAVDFQNKTSTIKEKTVGN VLSNAKVYFMFNKNEQTLSDDIDKALQEIIDDGTLKRLSLKWLGDDYSKEQY*" gene complement(2872198..2873010) /gene="tcyK" /locus_tag="BSU_29370" /old_locus_tag="BSU29370" CDS complement(2873024..2873833) /gene="tcyJ" /locus_tag="BSU_29380" /old_locus_tag="BSU29380" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:10939241, 11423008, 15262924, 23944997" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10939241, 11423008, 15262924, 23944997; Product type t: transporter" /codon_start=1 /transl_table=11 /product="sulfur containing amino acid ABC transporter binding lipoprotein" /protein_id="NP_390816.1" /db_xref="EnsemblGenomes-Gn:BSU29380" /db_xref="EnsemblGenomes-Tr:CAB14898" /db_xref="GOA:O34406" /db_xref="InterPro:IPR001638" /db_xref="SubtiList:BG13884" /db_xref="UniProtKB/Swiss-Prot:O34406" /translation="MNKRKGLVLLLSVFALLGGGCSQTNNKTDRQAQTVIVGTGTDFP NIAFLNEKGELTGYDIEVMKAIDKELPQYTFEFKTMDFSNLLTSLGNKKIDVIAHNMA KNKEREKRFLYHKVPYNYSPMYITVKEDNHKIHTLKDLHGKTVIVGATSNAADYITKY NKTHGSPIHLKYAGQGSNDTANQIETGRADATIATPFAVDFQNKTHAFRQKTVGDVLL DTEVYFMFNKGSQTLADDTDQAIKKLEKNGTLKKLSRKWLGADYSKSSFEK*" gene complement(2873024..2873833) /gene="tcyJ" /locus_tag="BSU_29380" /old_locus_tag="BSU29380" CDS complement(2873847..2874383) /gene="snaA" /locus_tag="BSU_29390" /old_locus_tag="BSU29390" /function="16.8: Protect" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:11390694, 11423008, 16109943, 23944997" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11390694, 11423008, 16109943, 23944997; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="N-acetyltransferase acting on sulfur compounds" /protein_id="NP_390817.1" /db_xref="EnsemblGenomes-Gn:BSU29390" /db_xref="EnsemblGenomes-Tr:CAB14899" /db_xref="GOA:O34350" /db_xref="InterPro:IPR000182" /db_xref="InterPro:IPR016181" /db_xref="SubtiList:BG13883" /db_xref="UniProtKB/Swiss-Prot:O34350" /translation="MSDDIFRLATVEDASELLKLVNSAFQPIRQLDIDWPSTRADIQM VSENIEHHSAIVLERDGKLISTITIRFPWESETPPSKYPFVWWFATLPEYKGQGAGSK LLTYVEEKVLRDMLKAPALTLGTSARKHPWLADMYRRRGYEVYFEQEKDGDIGVMMHK VLIPERFNPTLLGAPSWA*" gene complement(2873847..2874383) /gene="snaA" /locus_tag="BSU_29390" /old_locus_tag="BSU29390" promotor_-35 2874420..2874427 /Source="Nicolas_upshift_promotors" /id="U2271" /multdbtbs="SigA,SigA" /comp="M17" /sig="SigA" /pcomp="0.357642357642358" /psig=1 /xcortree=1744 /SigmaFactorBS="ttttgtcactcctcttcacaaaatatataattcctaTTTGTT TActaagcttttattGTTTATACTATAAAGCATACtctgatctttgactaatcaaaaa a" /listShort="S1115, ytlI" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(2874438..2874457) /Source="Nicolas_upshift_promotors" /id="U2272" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.673326673326673" /psig=1 /xcortree=1739 /SigmaFactorBS="tcattaaaattactgaagtgaaggtttactttttttGATTAG TCaaagatcagagtaTGCTTTATAGTATAAACAATaaaagcttagtaaacaaatagga a" /listShort="ytmI, tcyJ, tcyK, tcyL, tcyM, tcyN, ytmO, ytnI, ytnJ, rbfK, ytnL, ytnM, ytoI" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-10 2874441..2874460 /Source="Nicolas_upshift_promotors" /id="U2271" /multdbtbs="SigA,SigA" /comp="M17" /sig="SigA" /pcomp="0.357642357642358" /psig=1 /xcortree=1744 /SigmaFactorBS="ttttgtcactcctcttcacaaaatatataattcctaTTTGTT TActaagcttttattGTTTATACTATAAAGCATACtctgatctttgactaatcaaaaa a" /listShort="S1115, ytlI" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 2874444..2874535 /Source="Nicolas_S_feature" /locus_tag="new_3008846_3008937" /HighExp="dia5, MG 5, UNK1, MG t5, MG 10, B60, dia0, nit, Diami, BT" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1115" upshifts 2874444 /Source="Nicolas_upshifts" /id="U2271" /multdbtbs="SigA,SigA" /comp="M17" /sig="SigA" /pcomp="0.357642357642358" /psig=1 /xcortree=1744 /SigmaFactorBS="ttttgtcactcctcttcacaaaatatataattcctaTTTGTT TActaagcttttattGTTTATACTATAAAGCATACtctgatctttgactaatcaaaaa a" /listShort="S1115, ytlI" /GFF_Attribute="listLong" upshifts complement(2874454) /Source="Nicolas_upshifts" /id="U2272" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.673326673326673" /psig=1 /xcortree=1739 /SigmaFactorBS="tcattaaaattactgaagtgaaggtttactttttttGATTAG TCaaagatcagagtaTGCTTTATAGTATAAACAATaaaagcttagtaaacaaatagga a" /listShort="ytmI, tcyJ, tcyK, tcyL, tcyM, tcyN, ytmO, ytnI, ytnJ, rbfK, ytnL, ytnM, ytoI" /GFF_Attribute="listLong" promotor_-35 complement(2874471..2874478) /Source="Nicolas_upshift_promotors" /id="U2272" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.673326673326673" /psig=1 /xcortree=1739 /SigmaFactorBS="tcattaaaattactgaagtgaaggtttactttttttGATTAG TCaaagatcagagtaTGCTTTATAGTATAAACAATaaaagcttagtaaacaaatagga a" /listShort="ytmI, tcyJ, tcyK, tcyL, tcyM, tcyN, ytmO, ytnI, ytnJ, rbfK, ytnL, ytnM, ytoI" /GFF_Attribute="listLong" /label="promotor_-35" CDS 2874536..2875462 /gene="ascR" /locus_tag="BSU_29400" /old_locus_tag="BSU29400" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:11390694, 11423008, 15272571, 16109943, 16513748, 22212096, 23944997" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11390694, 11423008, 15272571, 16109943, 16513748, 22212096, 23944997; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator of operon snaA-ytnM degrading cysteine-containing compounds (AscR-N-acetylcysteine)" /protein_id="NP_390818.1" /db_xref="EnsemblGenomes-Gn:BSU29400" /db_xref="EnsemblGenomes-Tr:CAB14900" /db_xref="GOA:O35038" /db_xref="InterPro:IPR000847" /db_xref="InterPro:IPR005119" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG13877" /db_xref="UniProtKB/Swiss-Prot:O35038" /translation="MELRSIKTFHTIVKFGSFYKAAEILNYSQPTISMRMKQLEQDLG VLLFERGKSLQLTKAGKLFYERTGDLLMQYEALKHNLSDLKEEEAGIINIGVSEPTAS LIFPEILKDFLMDYPKITVNIKVDDANTCSQKLLDGTIDFAVCGEPELILENYYHPFF YDTLNVIVSDQHPLAEKKAVHLSDLAEERFIFTPANCPIRLQIEQHLHRELGNRYKKM ELTSSMSHEYYVRENIGISIFTSTAHSKPFNGTKVIPILNLDITPPIGLLTNQKEVHF DRATKDLIARITKRFQQRSKELEGTSDKTITG*" gene 2874536..2875462 /gene="ascR" /locus_tag="BSU_29400" /old_locus_tag="BSU29400" S_feature complement(2874938..2875467) /Source="Nicolas_S_feature" /locus_tag="new_3009340_3009869_c" /HighExp="Etha, dia15, dia5, H2O2, M9-stat, M40t90, Sw, Gly, M0t90, Cold" /AntisenseName="ytlI" /AntisenseCor="-7.8012588423369304E-3" /AntisenseRegPval=0 /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S1116" downshifts complement(2875512) /Source="Nicolas_upshifts" /id="D1503" /incds=0 /nref=142 /ntot=251 /MaxReadThrough="4.32965" /MaxDrop="5.01142" /score="39.1547987" /energy="-16.5" /TU="U2273" /idTUdmin="U2274" /TUdmin=20 /isTUend="TRUE" CDS complement(2875513..2876196) /gene="ytkL" /locus_tag="BSU_29410" /old_locus_tag="BSU29410" /function="16.11: Scavenge (Catabolism)" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative metal-dependent hydrolase" /protein_id="NP_390819.2" /db_xref="EnsemblGenomes-Gn:BSU29410" /db_xref="EnsemblGenomes-Tr:CAB14901" /db_xref="GOA:Q795U4" /db_xref="InterPro:IPR001279" /db_xref="InterPro:IPR022877" /db_xref="InterPro:IPR036866" /db_xref="SubtiList:BG13871" /db_xref="UniProtKB/Swiss-Prot:Q795U4" /translation="MKVTYHGHSVITVETKDHHIIFDPFLTGNSLTDIKPEDVKADVI LLTHGHNDHVGDTEQIAKQNNALVIAPNELAVYLGWKGLNVHPMHIGGSRQFDFGKVK LTQAFHGSAITDEENKTITYTGMPAGILLTVEDKTIFHAGDTALFSDMKLIGELNHID LAFLPIGDNFTMGPEDAKLAAEWLRAKQVVPVHYNTFPVIEQDPEAFADSLPGGVGKV MSVGETIEL*" gene complement(2875513..2876196) /gene="ytkL" /locus_tag="BSU_29410" /old_locus_tag="BSU29410" S_feature complement(2876197..2876258) /Source="Nicolas_S_feature" /locus_tag="new_3010599_3010660_c" /HighExp="dia15, Etha, dia5, Diami, H2O2, M0t90, M40t90, Salt, LBGtran, Lbtran" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="0.999, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S1117" CDS complement(2876259..2877026) /gene="ytkK" /locus_tag="BSU_29420" /old_locus_tag="BSU29420" /EC_number="1.1.1.-" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative 3-oxoacyl-acyl-carrier protein reductase" /protein_id="NP_390820.1" /db_xref="EnsemblGenomes-Gn:BSU29420" /db_xref="EnsemblGenomes-Tr:CAB14902" /db_xref="GOA:O34308" /db_xref="InterPro:IPR002347" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG13870" /db_xref="UniProtKB/Swiss-Prot:O34308" /translation="MRHALITAGSKGLGRKVTETLLAKGYSVTVNYRQDEEAVSRLKE ACPDCLDRLQFVKGDVTKKEDLLRIAEAALNRFGRIDFLINNAGPYIFERKKLADYTD DEWYGMLEGNLSAVFHLFKAVIPIMRKQQFGRIITYGFQGAAHAPGWLHRSAFGAAKV GLASLTKTIAIEEAEFGITANMVCPGDIVGDMKEASIEEARMRIGKEKTPIGRSGTGE DIARIIAFLCEENSDLVTGTVIEATGGLNVINKNQTT*" gene complement(2876259..2877026) /gene="ytkK" /locus_tag="BSU_29420" /old_locus_tag="BSU29420" promotor_-10 complement(2877071..2877090) /Source="Nicolas_upshift_promotors" /id="U2273" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.772227772227772" /psig="0.999000999001" /xcortree=1987 /SigmaFactorBS="agctgtctgtacaggcagctttttttgtatgccaaagtgtaa aaaGTGatattgcaagcctttTATAGTAAAGTAGAAGAAGAaacactttattgaaagc g" /listShort="ytkK, S1117, ytkL, S1116" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2877093) /Source="Nicolas_upshifts" /id="U2273" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.772227772227772" /psig="0.999000999001" /xcortree=1987 /SigmaFactorBS="agctgtctgtacaggcagctttttttgtatgccaaagtgtaa aaaGTGatattgcaagcctttTATAGTAAAGTAGAAGAAGAaacactttattgaaagc g" /listShort="ytkK, S1117, ytkL, S1116" /GFF_Attribute="listLong" promotor_-35 complement(2877106..2877108) /Source="Nicolas_upshift_promotors" /id="U2273" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.772227772227772" /psig="0.999000999001" /xcortree=1987 /SigmaFactorBS="agctgtctgtacaggcagctttttttgtatgccaaagtgtaa aaaGTGatattgcaagcctttTATAGTAAAGTAGAAGAAGAaacactttattgaaagc g" /listShort="ytkK, S1117, ytkL, S1116" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2877153..2877389) /gene="ytzD" /locus_tag="BSU_29430" /old_locus_tag="BSU29430" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 11423008" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_390821.3" /db_xref="EnsemblGenomes-Gn:BSU29430" /db_xref="EnsemblGenomes-Tr:CAB14903" /db_xref="SubtiList:BG13938" /db_xref="UniProtKB/Swiss-Prot:O34503" /translation="MKKRKLAWQQEFVKISFIKSRHYSQPTSIMMGGRMMKKEPERYI YDEQESQETTRLISEAYQSGYVDMPDQESSSPAE*" gene complement(2877153..2877389) /gene="ytzD" /locus_tag="BSU_29430" /old_locus_tag="BSU29430" downshifts 2877238 /Source="Nicolas_upshifts" /id="D1504" /incds=0 /nref=1 /ntot=12 /MaxReadThrough="0.55049" /MaxDrop="4.17437" /score="-5.88070891" /energy="-8.9" /TU="NA" /idTUdmin="U2271" /TUdmin=1782 /isTUend="FALSE" downshifts complement(2877258) /Source="Nicolas_upshifts" /id="D1505" /incds=0 /nref=199 /ntot=288 /MaxReadThrough="5.44889" /MaxDrop="6.29233" /score="21.2322542" /energy="-8.5" /TU="U2274" /idTUdmin="U2274" /TUdmin="-1726" /isTUend="FALSE" CDS complement(2877349..2878734) /gene="argH" /locus_tag="BSU_29440" /old_locus_tag="BSU29440" /EC_number="4.3.2.1" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:2989674, 9890879, 11423008" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 2989674, 9890879, 11423008; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="argininosuccinate lyase" /protein_id="NP_390822.1" /db_xref="EnsemblGenomes-Gn:BSU29440" /db_xref="EnsemblGenomes-Tr:CAB14904" /db_xref="GOA:O34858" /db_xref="InterPro:IPR000362" /db_xref="InterPro:IPR008948" /db_xref="InterPro:IPR009049" /db_xref="InterPro:IPR020557" /db_xref="InterPro:IPR022761" /db_xref="InterPro:IPR024083" /db_xref="InterPro:IPR029419" /db_xref="SubtiList:BG12571" /db_xref="UniProtKB/Swiss-Prot:O34858" /translation="MKKLWGGRFQKTPEKWVDEFGASISFDQNLVAEDITGSLAHAAM LKKCGILTAEEELKIREGLNTLLQKAEEGALEFSVDYEDIHLNIEKMLIDEIGPLGGK LHTGRSRNDQVATDMHLYLKNHVGHIIELIEAFQSALIEKAEANVETILPGYTHLQRA QPISFAHHLLAYFWMLERDKERFQDSMKRINKSPLGCGALAGTTFPIDRDYSAELLGF DAIYENSLDGVSDRDFILEFLSNSSMLMMHLSRFSEEIILWCSQEFKFIELDDTYATG SSMMPQKKNPDMAELIRGKTGRVYGDMMGLFTIMKGLPLAYNKDLQEDKEGMFDTVKT VEGSLQIFTGMIQTMTVNKDVMKQATKQDFSNATELADYLAKKGMPFREAHEVVGKLV YTCIERGIYLSDMPFGEFQQASTLFEEDIYTVLDPYYAVEKRMSAGGTGFKQVEQALE KAKACVAAGVC*" gene complement(2877349..2878734) /gene="argH" /locus_tag="BSU_29440" /old_locus_tag="BSU29440" CDS complement(2878731..2879942) /gene="argG" /locus_tag="BSU_29450" /old_locus_tag="BSU29450" /EC_number="6.3.4.5" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:2989674, 11423008, 12963366, 17611193" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 2989674, 11423008, 12963366, 17611193; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="argininosuccinate synthase" /protein_id="NP_390823.1" /db_xref="EnsemblGenomes-Gn:BSU29450" /db_xref="EnsemblGenomes-Tr:CAB14905" /db_xref="GOA:O34347" /db_xref="InterPro:IPR001518" /db_xref="InterPro:IPR014729" /db_xref="InterPro:IPR018223" /db_xref="InterPro:IPR023434" /db_xref="InterPro:IPR024074" /db_xref="SubtiList:BG12570" /db_xref="UniProtKB/Swiss-Prot:O34347" /translation="MSEQKKVVLAYSGGLDTSVAIKWLQEQGYNVIACCLDVGEGKDL AFVQQKALEVGATNSYVIDAKEEFAQDYALISLQAHTMYEGKYPLVSALSRPLIAKKL VEIAEKEDAQAIAHGCTGKGNDQVRFEVSIKSLNPDLEVIAPVREWQWSREEEIEYAA SRGIPIPINLDSPYSIDQNLWGRANECGILEDPWAAPPEGAYDLTAPLEKTPDTPEVI EIAFEQGVPVSIDGVSYSLSELILKLNEMAGAHGVGRIDHVENRLVGIKSREVYECPG AMTLIKAHKELEDLTLVKEVAHFKPIIEQKMSEIIYNGLWFSPLKDALHAFLKETQKH VTGIVRVKLFKGHAIVEGRKSEYSLYDEKLATYTKDDAFDHHAAIGFIELWGLPTKVN SIVKKKEQIKA*" gene complement(2878731..2879942) /gene="argG" /locus_tag="BSU_29450" /old_locus_tag="BSU29450" S_feature complement(2879943..2880020) /Source="Nicolas_S_feature" /locus_tag="new_3014345_3014422_c" /HighExp="S1, MG 15, T3.0H, T3.30H, T4.0H, T5.0H, BMM, T2.30H, T-0.40H, T-1.10H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1118" promotor_-10 complement(2880013..2880032) /Source="Nicolas_upshift_promotors" /id="U2274" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.924075924075924" /psig=1 /xcortree=2914 /SigmaFactorBS="ttaggtgaagttttttttataaaagGCTTGAAAaaacgaaac gtactTGTTAAAGTGTATACATACAaaatgtatttttattaaatataatttattttta t" /listShort="S1118, argG, argH, ytzD, ytkK, S1117, ytkL" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2880019) /Source="Nicolas_upshifts" /id="U2274" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.924075924075924" /psig=1 /xcortree=2914 /SigmaFactorBS="ttaggtgaagttttttttataaaagGCTTGAAAaaacgaaac gtactTGTTAAAGTGTATACATACAaaatgtatttttattaaatataatttattttta t" /listShort="S1118, argG, argH, ytzD, ytkK, S1117, ytkL" /GFF_Attribute="listLong" promotor_-35 complement(2880047..2880054) /Source="Nicolas_upshift_promotors" /id="U2274" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.924075924075924" /psig=1 /xcortree=2914 /SigmaFactorBS="ttaggtgaagttttttttataaaagGCTTGAAAaaacgaaac gtactTGTTAAAGTGTATACATACAaaatgtatttttattaaatataatttattttta t" /listShort="S1118, argG, argH, ytzD, ytkK, S1117, ytkL" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2880112..2880624) /gene="moaB" /locus_tag="BSU_29460" /old_locus_tag="BSU29460" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 15269205, 20054111, 23680484; Product type f: factor" /codon_start=1 /transl_table=11 /product="molybdopterin GTP-binding precursor Z biosynthesis component" /protein_id="NP_390824.1" /db_xref="EnsemblGenomes-Gn:BSU29460" /db_xref="EnsemblGenomes-Tr:CAB14924" /db_xref="GOA:O34457" /db_xref="InterPro:IPR001453" /db_xref="InterPro:IPR008284" /db_xref="InterPro:IPR012245" /db_xref="InterPro:IPR036425" /db_xref="SubtiList:BG12618" /db_xref="UniProtKB/Swiss-Prot:O34457" /translation="MSVQEHKQEAPDIVRCKVITVSDTRTDETDKSGKLMISFLEEAG HHIAAYEIVKDEKDALQRSVLAGCMDEQTDAVLLNGGTGIADRDVTIEAITPLFSKEL PGFGEIFRMLSYTEDIGSAAIMSRATAGVIQHTAVFSTPGSSGAVKLAMNKLIIPELA HVVREIRKDK*" gene complement(2880112..2880624) /gene="moaB" /locus_tag="BSU_29460" /old_locus_tag="BSU29460" downshifts complement(2880130) /Source="Nicolas_upshifts" /id="D1506" /incds=0 /nref=122 /ntot=221 /MaxReadThrough="1.48097" /MaxDrop="4.78155" /score="25.7910606" /energy="-10.8" /TU="NA" /idTUdmin="U2275" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(2880650..2880669) /Source="Nicolas_upshift_promotors" /id="U2275" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.878121878121878" /psig=1 /xcortree=109 /SigmaFactorBS="agcaaaataaatcgcatgaaagcacattCTCTTGAAtgtgct tttttgtTGATGCATGATAGTGACAGAcagaaaacataaaagaggtgggccaatgagc g" /listShort="moaB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2880658) /Source="Nicolas_upshifts" /id="U2275" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.878121878121878" /psig=1 /xcortree=109 /SigmaFactorBS="agcaaaataaatcgcatgaaagcacattCTCTTGAAtgtgct tttttgtTGATGCATGATAGTGACAGAcagaaaacataaaagaggtgggccaatgagc g" /listShort="moaB" /GFF_Attribute="listLong" promotor_-35 complement(2880683..2880690) /Source="Nicolas_upshift_promotors" /id="U2275" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.878121878121878" /psig=1 /xcortree=109 /SigmaFactorBS="agcaaaataaatcgcatgaaagcacattCTCTTGAAtgtgct tttttgtTGATGCATGATAGTGACAGAcagaaaacataaaagaggtgggccaatgagc g" /listShort="moaB" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2880709..2881896) /gene="ackA" /locus_tag="BSU_29470" /old_locus_tag="BSU29470" /EC_number="2.7.2.1" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:8226682, 9811655, 11244084, 16995897, 19019159, 26098117" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8226682, 9811655, 11244084, 16995897, 19019159, 26098117; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="acetate kinase" /protein_id="NP_390825.1" /db_xref="EnsemblGenomes-Gn:BSU29470" /db_xref="EnsemblGenomes-Tr:CAB14925" /db_xref="GOA:P37877" /db_xref="InterPro:IPR000890" /db_xref="InterPro:IPR004372" /db_xref="InterPro:IPR023865" /db_xref="SubtiList:BG10813" /db_xref="UniProtKB/Swiss-Prot:P37877" /translation="MSKIIAINAGSSSLKFQLFEMPSETVLTKGLVERIGIADSVFTI SVNGEKNTEVTDIPDHAVAVKMLLNKLTEFGIIKDLNEIDGIGHRVVHGGEKFSDSVL LTDETIKEIEDISELAPLHNPANIVGIKAFKEVLPNVPAVAVFDTAFHQTMPEQSYLY SLPYEYYEKFGIRKYGFHGTSHKYVTERAAELLGRPLKDLRLISCHLGNGASIAAVEG GKSIDTSMGFTPLAGVAMGTRSGNIDPALIPYIMEKTGQTADEVLNTLNKKSGLLGIS GFSSDLRDIVEATKEGNERAETALEVFASRIHKYIGSYAARMSGVDAIIFTAGIGENS VEVRERVLRGLEFMGVYWDPALNNVRGEEAFISYPHSPVKVMIIPTDEEVMIARDVVR LAK*" gene complement(2880709..2881896) /gene="ackA" /locus_tag="BSU_29470" /old_locus_tag="BSU29470" downshifts complement(2880724) /Source="Nicolas_upshifts" /id="D1507" /incds=0 /nref=13 /ntot=117 /MaxReadThrough="5.03131" /MaxDrop="3.1641" /score="19.2403206" /energy="-9.9" /TU="U2276" /idTUdmin="U2277" /TUdmin=242 /isTUend="FALSE" S_feature complement(2881897..2882001) /Source="Nicolas_S_feature" /locus_tag="new_3016299_3016403_c" /HighExp="dia0, Lbexp, LBGtran, Oxctl, LPh, M0t45, HPh, Paraq, H2O2, G180" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigGF" /TUshortPSig="0.999, 0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S1119" promotor_-10 complement(2881986..2882005) /Source="Nicolas_upshift_promotors" /id="U2276" /multdbtbs="SigA" /comp="M16" /sig="SigA" /pcomp="0.918081918081918" /psig="0.999000999001" /xcortree=2694 /SigmaFactorBS="gacttcttattgtaagcgttatcaatacgcaagttgACTTGa aaagccgacatgacAATGTTTAAATGGAAAAGTCagatatttttcggagaagatgttg a" /listShort="S1119, ackA, moaB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2882001) /Source="Nicolas_upshifts" /id="U2276" /multdbtbs="SigA" /comp="M16" /sig="SigA" /pcomp="0.918081918081918" /psig="0.999000999001" /xcortree=2694 /SigmaFactorBS="gacttcttattgtaagcgttatcaatacgcaagttgACTTGa aaagccgacatgacAATGTTTAAATGGAAAAGTCagatatttttcggagaagatgttg a" /listShort="S1119, ackA, moaB" /GFF_Attribute="listLong" S_feature complement(2882003..2882132) /Source="Nicolas_S_feature" /locus_tag="new_3016405_3016534_c" /HighExp="S5, S6, S7, S8, S4, dia5, BT, H2O2, dia15, M40t90" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigGF" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S1120" promotor_-35 complement(2882021..2882025) /Source="Nicolas_upshift_promotors" /id="U2276" /multdbtbs="SigA" /comp="M16" /sig="SigA" /pcomp="0.918081918081918" /psig="0.999000999001" /xcortree=2694 /SigmaFactorBS="gacttcttattgtaagcgttatcaatacgcaagttgACTTGa aaagccgacatgacAATGTTTAAATGGAAAAGTCagatatttttcggagaagatgttg a" /listShort="S1119, ackA, moaB" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2882069..2882272) /locus_tag="BSU_29479" /old_locus_tag="BSU29479" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_009513997.1" /translation="MMNGLKKKSKCFKSSLDSRMRSMPKLLLFMLLKTGLDELNPALK HKIQREKPQIVSVHQYKTYSECV*" gene complement(2882069..2882272) /locus_tag="BSU_29479" /old_locus_tag="BSU29479" promotor_-10 complement(2882130..2882141) /Source="Nicolas_upshift_promotors" /id="U2277" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=888 /SigmaFactorBS="tttatttatgcttttgaagaccggacttgaCGAATTGaatcc agctttgaaACACAAAATACAgagggaaaaaccgcaaattgtaagcgttcatcaatac a" /listShort="S1120, S1119, ackA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2882132) /Source="Nicolas_upshifts" /id="U2277" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=888 /SigmaFactorBS="tttatttatgcttttgaagaccggacttgaCGAATTGaatcc agctttgaaACACAAAATACAgagggaaaaaccgcaaattgtaagcgttcatcaatac a" /listShort="S1120, S1119, ackA" /GFF_Attribute="listLong" promotor_-35 complement(2882156..2882162) /Source="Nicolas_upshift_promotors" /id="U2277" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=888 /SigmaFactorBS="tttatttatgcttttgaagaccggacttgaCGAATTGaatcc agctttgaaACACAAAATACAgagggaaaaaccgcaaattgtaagcgttcatcaatac a" /listShort="S1120, S1119, ackA" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2882244..2883233) /gene="ytxK" /locus_tag="BSU_29480" /old_locus_tag="BSU29480" /function="16.6: Maintain" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative nucleic acid methyltransferase" /protein_id="NP_390826.1" /db_xref="EnsemblGenomes-Gn:BSU29480" /db_xref="EnsemblGenomes-Tr:CAB14926" /db_xref="GOA:P37876" /db_xref="InterPro:IPR003356" /db_xref="InterPro:IPR016843" /db_xref="InterPro:IPR029063" /db_xref="SubtiList:BG10812" /db_xref="UniProtKB/Swiss-Prot:P37876" /translation="MQKDHVGAVYELLNEAAIMIKNELQISYIEALAEAGEMYFLEKT DQLKLPADQKTKQLQALLEKAEFGTYEHEWVRKAFQLAVLKGMKDISHPNRQMTPDTI GLFISYLVNKFMADKKELTILDPALGTGNLLFTVLNQLSEKTANSFGIEIDDVLLKIA YAQANLLKKELELFHQDSLEPLFIDPVDTVICDLPVGYYPNDEGAEAFELKADEGHSF AHHLFIEQSVKHTKPGGYLFFMIPNHLFESSQSGKLKQFFKDKVHINALLQLPKSIFK DEAHAKSILVLQKQGENTKAPGQILLANLPSFSNQKAMLDMMAQFDEWFKKEK*" gene complement(2882244..2883233) /gene="ytxK" /locus_tag="BSU_29480" /old_locus_tag="BSU29480" downshifts complement(2882262) /Source="Nicolas_upshifts" /id="D1508" /incds=0 /nref=158 /ntot=243 /MaxReadThrough="3.51469" /MaxDrop="5.25938" /score="-4.33730173" /energy="-13.3" /TU="NA" /idTUdmin="U2279" /TUdmin="-20" /isTUend="TRUE" CDS complement(2883294..2883797) /gene="tpx" /locus_tag="BSU_29490" /old_locus_tag="BSU29490" /EC_number="1.11.1.15" /function="16.6: Maintain" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:12486061, 18588855, 18588855, 23899494, 25355936, 25852656" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12486061, 18588855, 18588855, 23899494, 25355936, 25852656; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="thiol peroxidase (lipid hydroperoxide reductase)" /protein_id="NP_390827.1" /db_xref="EnsemblGenomes-Gn:BSU29490" /db_xref="EnsemblGenomes-Tr:CAB14927" /db_xref="GOA:P80864" /db_xref="InterPro:IPR002065" /db_xref="InterPro:IPR013740" /db_xref="InterPro:IPR013766" /db_xref="InterPro:IPR018219" /db_xref="InterPro:IPR036249" /db_xref="PDB:2JSY" /db_xref="PDB:2JSZ" /db_xref="SubtiList:BG13855" /db_xref="UniProtKB/Swiss-Prot:P80864" /translation="MAEITFKGGPVTLVGQEVKVGDQAPDFTVLTNSLEEKSLADMKG KVTIISVIPSIDTGVCDAQTRRFNEEAAKLGDVNVYTISADLPFAQARWCGANGIDKV ETLSDHRDMSFGEAFGVYIKELRLLARSVFVLDENGKVVYAEYVSEATNHPNYEKPIE AAKALVK*" gene complement(2883294..2883797) /gene="tpx" /locus_tag="BSU_29490" /old_locus_tag="BSU29490" downshifts complement(2883300) /Source="Nicolas_upshifts" /id="D1509" /incds=0 /nref=53 /ntot=241 /MaxReadThrough="6.94509" /MaxDrop="4.3179" /score="9.29337297" /energy="-10.1" /TU="U2279" /idTUdmin="U2280" /TUdmin=548 /isTUend="FALSE" promotor_no_box 2883514..2883614 /Source="Nicolas_upshift_promotors" /id="U2278" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.924075924075924" /psig="0.001998001998002" /xcortree=44 /SigmaFactorBS="ccgcaccagcgcgcttgcgcgaatggaaggtctgcactgatt gtgtagacgttgacatctccaagctttgcagcttcttcgttaaaacggcgtgtttgtg c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_no_box" upshifts 2883574 /Source="Nicolas_upshifts" /id="U2278" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.924075924075924" /psig="0.001998001998002" /xcortree=44 /SigmaFactorBS="ccgcaccagcgcgcttgcgcgaatggaaggtctgcactgatt gtgtagacgttgacatctccaagctttgcagcttcttcgttaaaacggcgtgtttgtg c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" downshifts 2883793 /Source="Nicolas_upshifts" /id="D1510" /incds=0 /nref=86 /ntot=184 /MaxReadThrough="2.23568" /MaxDrop="5.49495" /score="20.1242958" /energy="-12.7" /TU="NA" /idTUdmin="U2278" /TUdmin="-1" /isTUend="TRUE" promotor_-10 complement(2883820..2883839) /Source="Nicolas_upshift_promotors" /id="U2279" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.867132867132867" /psig=1 /xcortree=2364 /SigmaFactorBS="actgcgctggccgcagttaacttttttttggcataaACTTTG CAgtttgcaggaaacTTTACTATGATAGAGACATAcatacaaaagggaggaattataa t" /listShort="tpx, ytxK" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2883836) /Source="Nicolas_upshifts" /id="U2279" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.867132867132867" /psig=1 /xcortree=2364 /SigmaFactorBS="actgcgctggccgcagttaacttttttttggcataaACTTTG CAgtttgcaggaaacTTTACTATGATAGAGACATAcatacaaaagggaggaattataa t" /listShort="tpx, ytxK" /GFF_Attribute="listLong" promotor_-35 complement(2883853..2883860) /Source="Nicolas_upshift_promotors" /id="U2279" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.867132867132867" /psig=1 /xcortree=2364 /SigmaFactorBS="actgcgctggccgcagttaacttttttttggcataaACTTTG CAgtttgcaggaaacTTTACTATGATAGAGACATAcatacaaaagggaggaattataa t" /listShort="tpx, ytxK" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2883907..2884362) /gene="gerW" /locus_tag="BSU_29500" /old_locus_tag="BSU29500" /experiment="publication(s) with functional evidences, PMID:23921501, 25790435, 27881417" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 23921501, 25790435, 27881417; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="germination-associated protein" /protein_id="NP_390828.1" /db_xref="EnsemblGenomes-Gn:BSU29500" /db_xref="EnsemblGenomes-Tr:CAB14928" /db_xref="GOA:O34806" /db_xref="InterPro:IPR014229" /db_xref="SubtiList:BG13849" /db_xref="UniProtKB/Swiss-Prot:O34806" /translation="MADHPIQGLMKTAMENLKEMIDVNTIIGDPVETPDGSVILTVSK VGFGFAAGGSEFGGKPAEKKSEDDETREQKLPFGGGSGGGVSITPIAFLIVGSTGIRM LHLDENTHLIEKILDAAPQTLERIQQMFKKNNKNQSQGQNQNQMNNMNY*" gene complement(2883907..2884362) /gene="gerW" /locus_tag="BSU_29500" /old_locus_tag="BSU29500" downshifts complement(2883935) /Source="Nicolas_upshifts" /id="D1511" /incds=0 /nref=38 /ntot=91 /MaxReadThrough="3.69502" /MaxDrop="5.65648" /score="26.1939476" /energy="-12.7" /TU="U2280" /idTUdmin="U2280" /TUdmin="-87" /isTUend="FALSE" CDS complement(2884376..2885056) /gene="ytfI" /locus_tag="BSU_29510" /old_locus_tag="BSU29510" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="conserved sporulation-related protein" /protein_id="NP_390829.1" /db_xref="EnsemblGenomes-Gn:BSU29510" /db_xref="EnsemblGenomes-Tr:CAB14929" /db_xref="InterPro:IPR021338" /db_xref="SubtiList:BG13848" /db_xref="UniProtKB/Swiss-Prot:O34917" /translation="MVYVLTAILILIGIVLLLRMKIHVALEYLHADDNDKLTLKITAL FGLIRIKKTIPAIKVNKEDGTVDIKQKTESKMKKSSGKKKITQNDVQQSINKIEMLLH QVTRLRKISASFLAHLHITKLEWVTVIGIQDAAVTGVLTGAVWGVKGGIAAMLYDHLD FVNKPVYEVIPSFQVPVSKTHFQCIFFFRFGHAMLAAFKFVKYGRELSVLKKNPSARM TSKNDSSV*" gene complement(2884376..2885056) /gene="ytfI" /locus_tag="BSU_29510" /old_locus_tag="BSU29510" upshifts complement(2884468) /Source="Nicolas_upshifts" /id="U2280" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=1136 /SigmaFactorBS="gtttccaagacccattttcagTGTATATtcttttttcgcttt GGACATGCTATGcttgcagctttcaaattcgtcaaatacggacgggagctatccgtat t" /listShort="ytfJ" /listLong="tpx, ytxK" promotor_-10 complement(2884475..2884486) /Source="Nicolas_upshift_promotors" /id="U2280" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=1136 /SigmaFactorBS="gtttccaagacccattttcagTGTATATtcttttttcgcttt GGACATGCTATGcttgcagctttcaaattcgtcaaatacggacgggagctatccgtat t" /listShort="ytfJ" /listLong="tpx, ytxK" /label="promotor_-10" promotor_-35 complement(2884501..2884507) /Source="Nicolas_upshift_promotors" /id="U2280" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=1136 /SigmaFactorBS="gtttccaagacccattttcagTGTATATtcttttttcgcttt GGACATGCTATGcttgcagctttcaaattcgtcaaatacggacgggagctatccgtat t" /listShort="ytfJ" /listLong="tpx, ytxK" /label="promotor_-35" downshifts complement(2884794) /Source="Nicolas_upshifts" /id="D1512" /incds=1 /nref=1 /ntot=1 /MaxReadThrough="4.64036" /MaxDrop="2.98792" /score="28.0381876" /energy="-11.8" /TU="U2281" /idTUdmin="U2281" /TUdmin="-308" /isTUend="FALSE" promotor_-10 complement(2885069..2885087) /Source="Nicolas_upshift_promotors" /id="U2281" /multdbtbs="SigF" /comp="M3" /sig="SigEF" /pcomp="0.516483516483517" /psig="0.516483516483517" /xcortree=1030 /SigmaFactorBS="ataccgcaaataaccgataacccggacttccgtccgGGTTTA tttttttaggaattGGCGATAATGCTCCTAGAGgaagtgaagaatatggtgtatgtac t" /listShort="ytfI" /listLong="ytfJ, tpx, ytxK" /label="promotor_-10" upshifts complement(2885083) /Source="Nicolas_upshifts" /id="U2281" /multdbtbs="SigF" /comp="M3" /sig="SigEF" /pcomp="0.516483516483517" /psig="0.516483516483517" /xcortree=1030 /SigmaFactorBS="ataccgcaaataaccgataacccggacttccgtccgGGTTTA tttttttaggaattGGCGATAATGCTCCTAGAGgaagtgaagaatatggtgtatgtac t" /listShort="ytfI" /listLong="ytfJ, tpx, ytxK" promotor_-35 complement(2885102..2885107) /Source="Nicolas_upshift_promotors" /id="U2281" /multdbtbs="SigF" /comp="M3" /sig="SigEF" /pcomp="0.516483516483517" /psig="0.516483516483517" /xcortree=1030 /SigmaFactorBS="ataccgcaaataaccgataacccggacttccgtccgGGTTTA tttttttaggaattGGCGATAATGCTCCTAGAGgaagtgaagaatatggtgtatgtac t" /listShort="ytfI" /listLong="ytfJ, tpx, ytxK" /label="promotor_-35" CDS complement(2885131..2885625) /gene="yteJ" /locus_tag="BSU_29520" /old_locus_tag="BSU29520" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406, 23155385; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative integral inner membrane protein" /protein_id="NP_390830.1" /db_xref="EnsemblGenomes-Gn:BSU29520" /db_xref="EnsemblGenomes-Tr:CAB14930" /db_xref="GOA:O34424" /db_xref="InterPro:IPR010432" /db_xref="SubtiList:BG13840" /db_xref="UniProtKB/Swiss-Prot:O34424" /translation="MDATYEELERNDIKGPQEAELLTHAYAGFWVRFWAFLLDWLVIW GLNHLLVSPLFTVLDLPKTSGMFTFSAYSVTTLIVYLAYFALMTKYFRQTLGKMVFGL KVVSVKQDSKLTWSTVIFREVVGRYIDKIWILYIVVAFSPTKQGIHDYIADTTVVHEK LYRK*" gene complement(2885131..2885625) /gene="yteJ" /locus_tag="BSU_29520" /old_locus_tag="BSU29520" downshifts complement(2885146) /Source="Nicolas_upshifts" /id="D1513" /incds=0 /nref=240 /ntot=258 /MaxReadThrough="1.43721" /MaxDrop="6.8315" /score="28.0381876" /energy="-11.8" /TU="NA" /idTUdmin="U2282" /TUdmin=0 /isTUend="TRUE" CDS complement(2885638..2886645) /gene="sppA" /locus_tag="BSU_29530" /old_locus_tag="BSU29530" /function="16.1: Circulate" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:9987136, 10455123, 16484219, 22472423, 23155385, 24228759" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9987136, 10455123, 16484219, 22472423, 23155385, 24228759; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="signal peptide peptidase" /protein_id="NP_390831.1" /db_xref="EnsemblGenomes-Gn:BSU29530" /db_xref="EnsemblGenomes-Tr:CAB14931" /db_xref="GOA:O34525" /db_xref="InterPro:IPR002142" /db_xref="InterPro:IPR004635" /db_xref="InterPro:IPR029045" /db_xref="PDB:3RST" /db_xref="PDB:4KWB" /db_xref="SubtiList:BG13839" /db_xref="UniProtKB/Swiss-Prot:O34525" /translation="MNAKRWIALVIALGIFGVSIIVSISMSFFESVKGAQTDLTSLTD ESQEKTLENGSPSSKIAVLEVSGTIQDNGDSSSLLGADGYNHRTFLKNLERAKDDKTV KGIVLKVNSPGGGVYESAEIHKKLEEIKKETKKPIYVSMGSMAASGGYYISTAADKIF ATPETLTGSLGVIMESVNYSKLADKLGISFETIKSGAHKDIMSPSREMTKEEKNIMQS MVDNSYEGFVDVISKGRGMPKAEVKKIADGRVYDGRQAKKLNLVDELGFYDDTITAMK KDHKDLKNASVISYEESFGLGSLFSMGANKMFKSEIDFLNMREILSQSGSPRMMYLYA K*" gene complement(2885638..2886645) /gene="sppA" /locus_tag="BSU_29530" /old_locus_tag="BSU29530" promotor_-10 complement(2886669..2886684) /Source="Nicolas_upshift_promotors" /id="U2282" /multdbtbs="SigW" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1672 /SigmaFactorBS="cgtttgccggcagcccgttaagccggagctttctcatgaagT GAAACATTTttcatattgaaTCGTATAATGAGAGAGtttaggaaaaaggaggagaaaa a" /listShort="sppA, yteJ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2886686) /Source="Nicolas_upshifts" /id="U2282" /multdbtbs="SigW" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1672 /SigmaFactorBS="cgtttgccggcagcccgttaagccggagctttctcatgaagT GAAACATTTttcatattgaaTCGTATAATGAGAGAGtttaggaaaaaggaggagaaaa a" /listShort="sppA, yteJ" /GFF_Attribute="listLong" S_feature complement(2886688..2886767) /Source="Nicolas_S_feature" /locus_tag="new_3021090_3021169_c" /HighExp="LBGexp, Oxctl, LBGtran, dia0, H2O2, dia15, G180, G150, Paraq, Lbexp" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S1121" promotor_-35 complement(2886696..2886705) /Source="Nicolas_upshift_promotors" /id="U2282" /multdbtbs="SigW" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1672 /SigmaFactorBS="cgtttgccggcagcccgttaagccggagctttctcatgaagT GAAACATTTttcatattgaaTCGTATAATGAGAGAGtttaggaaaaaggaggagaaaa a" /listShort="sppA, yteJ" /GFF_Attribute="listLong" /label="promotor_-35" misc_feature 2886745..2886764 /Source="Nicolas_upshift_promotors" /id="U2283" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.783216783216783" /psig="0.982017982017982" /xcortree=384 /SigmaFactorBS="aaaatgtttcacttcatgagaaagctccggcttaacgggctg ccggcaaaCGTGGTACACTTATGGCCAAaggtattttatcacaaatactggatggcag a" /listShort="S1122, ppnKB" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 2886755 /Source="Nicolas_upshifts" /id="U2283" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.783216783216783" /psig="0.982017982017982" /xcortree=384 /SigmaFactorBS="aaaatgtttcacttcatgagaaagctccggcttaacgggctg ccggcaaaCGTGGTACACTTATGGCCAAaggtattttatcacaaatactggatggcag a" /listShort="S1122, ppnKB" /GFF_Attribute="listLong" promotor_-10 complement(2886760..2886779) /Source="Nicolas_upshift_promotors" /id="U2284" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.984015984015984" /psig="0.999000999001" /xcortree=2689 /SigmaFactorBS="ccatttcccctttgctgtcatatttaagTTTTTctgccatcc agtattTGTGATAAAATACCTTTGGCcataagtgtaccacgtttgccggcagcccgtt a" /listShort="S1121, sppA, yteJ" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 2886764..2886830 /Source="Nicolas_S_feature" /locus_tag="new_3021166_3021232" /HighExp="M0t90, Sw, M9-stat, BC, M40t90, T4.0H, T2.30H, S1, T3.30H, T2.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.982" /TUlongSig="NA" /TUlongPSig="NA" /label="S1122" upshifts complement(2886767) /Source="Nicolas_upshifts" /id="U2284" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.984015984015984" /psig="0.999000999001" /xcortree=2689 /SigmaFactorBS="ccatttcccctttgctgtcatatttaagTTTTTctgccatcc agtattTGTGATAAAATACCTTTGGCcataagtgtaccacgtttgccggcagcccgtt a" /listShort="S1121, sppA, yteJ" /GFF_Attribute="listLong" promotor_-35 complement(2886795..2886799) /Source="Nicolas_upshift_promotors" /id="U2284" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.984015984015984" /psig="0.999000999001" /xcortree=2689 /SigmaFactorBS="ccatttcccctttgctgtcatatttaagTTTTTctgccatcc agtattTGTGATAAAATACCTTTGGCcataagtgtaccacgtttgccggcagcccgtt a" /listShort="S1121, sppA, yteJ" /GFF_Attribute="listLong" /label="promotor_-35" CDS 2886831..2887634 /gene="ppnKB" /locus_tag="BSU_29540" /old_locus_tag="BSU29540" /EC_number="2.7.1.23" /function="16.7: Manage energy" /function="16.14: Store" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2b: Function from indirect experimental evidences (e.g. phenotypes); PubMedId: 12897004, 16233726, 16511117, 25643072; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="inorganic polyphosphate/ATP-NAD kinase" /protein_id="NP_390832.1" /db_xref="EnsemblGenomes-Gn:BSU29540" /db_xref="EnsemblGenomes-Tr:CAB14932" /db_xref="GOA:O34934" /db_xref="InterPro:IPR002504" /db_xref="InterPro:IPR016064" /db_xref="InterPro:IPR017437" /db_xref="InterPro:IPR017438" /db_xref="SubtiList:BG13837" /db_xref="UniProtKB/Swiss-Prot:O34934" /translation="MTDQRRNVYFFHKQDQETNEQARSLTQLAEEHGFTVVNQHSDAN IIASIGGDGTFLQAVRKTNFRDDCLYVGITKKGKAHLYCDFHSDEREKMVDAMTFEQI EVRKYPLIEVTVDQASPFHCLNEVSIRSSIIKTFVMDVLIDDLHFETFRGDGMIISTP TGSTAYNKSVAGAVVDPLLPCMQVSELASLNNNTYRTLGSPFVLSSDRKLTLRVVQDG NEHPIIGLDNEALSTRNVKTIEIKLSNKKIKTVKLKDNSFWEKVKRTFL*" gene 2886831..2887634 /gene="ppnKB" /locus_tag="BSU_29540" /old_locus_tag="BSU29540" downshifts 2887564 /Source="Nicolas_upshifts" /id="D1514" /incds=1 /nref=46 /ntot=222 /MaxReadThrough="5.39036" /MaxDrop="3.90238" /score="19.2746112" /energy="-13.8" /TU="U2283" /idTUdmin="U2283" /TUdmin="-124" /isTUend="FALSE" downshifts 2887622 /Source="Nicolas_upshifts" /id="D1515" /incds=0 /nref=6 /ntot=54 /MaxReadThrough="3.14676" /MaxDrop="4.64552" /score="19.2746112" /energy="-13.8" /TU="U2283" /idTUdmin="U2283" /TUdmin="-66" /isTUend="FALSE" CDS complement(2887666..2889255) /gene="ytcJ" /locus_tag="BSU_29550" /old_locus_tag="BSU29550" /EC_number="3.5.-.-" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 19433221, 20386924, 24826896; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative N-substituted formamide deformylase, dihydropyrimidinase or isoaspartyl peptidase" /protein_id="NP_390833.1" /db_xref="EnsemblGenomes-Gn:BSU29550" /db_xref="EnsemblGenomes-Tr:CAB14933" /db_xref="GOA:O34355" /db_xref="InterPro:IPR011059" /db_xref="InterPro:IPR013108" /db_xref="InterPro:IPR032466" /db_xref="InterPro:IPR033932" /db_xref="SubtiList:BG13835" /db_xref="UniProtKB/Swiss-Prot:O34355" /translation="MKAIWHGGFIYTMLEEGDRTEAVYVEDGVIKGTGSYERLKEKYG SPETEEISLNGAVMFPGFVDSHLHLIGHGEKQLQLDLSALTSKDSILQAAKERERQLP KNDWLIGEGWNENQFETPDYLTKHDLDRLFPDRPVLLKRICRHAIAVNSAALQAAGIS RNTPDPDGGVIVKDANGEPTGLLFDKAQDLILKAVPPVSQHYVDEALTAAIKDCWTKG LTGGHSEDLSYYGDVSVPMKAYEKAAAGGKYPFRCHLLVHHEAVDRWEQLEKLSGPYV EFGAMKIFADGALGGRTALLKEPYQDDPSTNGVQVHDDETLGRLIRKAREKGMEVAVH AIGDLAFEKVLNAIEKHPPKNGRHDRLIHAQVLDNELIERAARMPIALDLQPHFVASD FPWVIDRLGKDRMKTAFAWKTLISKGILCAGGSDAPIEPVDPLLGIQSAVLRKSSHEQ NGPSYNESECLPVYEAIKLYTEGSAGIIYKEKSRGKIAEGYDADFTVLSGDPFAIDPA QLHLLEIKKTVINGQIVYEKS*" gene complement(2887666..2889255) /gene="ytcJ" /locus_tag="BSU_29550" /old_locus_tag="BSU29550" downshifts complement(2887675) /Source="Nicolas_upshifts" /id="D1516" /incds=0 /nref=149 /ntot=255 /MaxReadThrough="2.61299" /MaxDrop="5.92403" /score="32.0110789" /energy="-13.8" /TU="NA" /idTUdmin="U2285" /TUdmin=1 /isTUend="TRUE" CDS complement(2889275..2890864) /gene="ytcI" /locus_tag="BSU_29560" /old_locus_tag="BSU29560" /EC_number="6.2.1.-" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative acyl-coenzyme A synthetase" /protein_id="NP_390834.2" /db_xref="EnsemblGenomes-Gn:BSU29560" /db_xref="EnsemblGenomes-Tr:CAB14934" /db_xref="GOA:C0SPB0" /db_xref="InterPro:IPR000873" /db_xref="InterPro:IPR020845" /db_xref="InterPro:IPR025110" /db_xref="SubtiList:BG13834" /db_xref="UniProtKB/Swiss-Prot:C0SPB0" /translation="MLKREDLIAPVQYNLVNEMEKFSAAGQKTALLWEDESGKQESWS YEKLMEETNKIGAALADLGFKKGDKLIVMVPRVLEAYAVYLAILKSGMVVIPCSEMLR AKDLEYRIEHAEVKGAIVYSEFIGAFRDVSTADKLITLSIGENDAGWKNLLSIEADGS QFKTADTTRDDMAFLSYTSGTTGQPKGVVHTHGWAFAHLKTSAGAWLDISEKDIVWAT AAPGWQKWVWSPFLAVLGSGATGFVYHGRFKAEKYLELLNRYKINVFCCTPTEYRLMA KVEGLKRFDLSALHSAVSAGEPLNREVIDVFQKHFGIKVRDGYGQTESTLLVGVLKDT PIKPGSMGKPTPGNQVEIINEDGEICKPGEVGDIAVHLSTPALFKEYFKDPERMKTQI RGDYFLTGDRARKDEEGYFWFESRNDDIIISSGYTIGPFEVEDALVKHPEVKECAVVA SPDEIRGSIVKAYVVLQNHEKRSDELVKMLQNHVKTITAPYKYPREIEFVESLPKTAS AKIRRVELRKREEQLKANKKA*" gene complement(2889275..2890864) /gene="ytcI" /locus_tag="BSU_29560" /old_locus_tag="BSU29560" promotor_-10 complement(2890910..2890927) /Source="Nicolas_upshift_promotors" /id="U2285" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.34965034965035" /psig="0.871128871128871" /xcortree=1876 /SigmaFactorBS="aaaggaccagcggcctataaaatctaTGTTTACagaggttgc ttttagGCATATCCTTACGGAAAGagcctgtatttatgtataatgggtggagaaagtg a" /listShort="ytcI, ytcJ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2890915) /Source="Nicolas_upshifts" /id="U2285" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.34965034965035" /psig="0.871128871128871" /xcortree=1876 /SigmaFactorBS="aaaggaccagcggcctataaaatctaTGTTTACagaggttgc ttttagGCATATCCTTACGGAAAGagcctgtatttatgtataatgggtggagaaagtg a" /listShort="ytcI, ytcJ" /GFF_Attribute="listLong" promotor_-35 complement(2890943..2890949) /Source="Nicolas_upshift_promotors" /id="U2285" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.34965034965035" /psig="0.871128871128871" /xcortree=1876 /SigmaFactorBS="aaaggaccagcggcctataaaatctaTGTTTACagaggttgc ttttagGCATATCCTTACGGAAAGagcctgtatttatgtataatgggtggagaaagtg a" /listShort="ytcI, ytcJ" /GFF_Attribute="listLong" /label="promotor_-35" downshifts complement(2891042) /Source="Nicolas_upshifts" /id="D1517" /incds=0 /nref=242 /ntot=266 /MaxReadThrough="2.32229" /MaxDrop="9.17935" /score="30.5720337" /energy="-13.3" /TU="NA" /idTUdmin="U2287" /TUdmin=0 /isTUend="TRUE" CDS complement(2891043..2891252) /gene="sspA" /locus_tag="BSU_29570" /old_locus_tag="BSU29570" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:2456528, 2468649, 3009398, 16707666" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 2456528, 2468649, 3009398, 16707666; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="small acid-soluble spore protein (alpha-type SASP)" /protein_id="NP_390835.1" /db_xref="EnsemblGenomes-Gn:BSU29570" /db_xref="EnsemblGenomes-Tr:CAB14935" /db_xref="GOA:P04831" /db_xref="InterPro:IPR001448" /db_xref="InterPro:IPR018126" /db_xref="SubtiList:BG10786" /db_xref="UniProtKB/Swiss-Prot:P04831" /translation="MANNNSGNSNNLLVPGAAQAIDQMKLEIASEFGVNLGADTTSRA NGSVGGEITKRLVSFAQQNMGGGQF*" gene complement(2891043..2891252) /gene="sspA" /locus_tag="BSU_29570" /old_locus_tag="BSU29570" promotor_-35 2891248..2891252 /Source="Nicolas_upshift_promotors" /id="U2286" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp=1 /psig=0 /xcortree=706 /SigmaFactorBS="tcgcttgagcagctcctggtactaaaaggttgttgctgttac ctgagttattgttaGCCATgtgtctcaCCTCCTTGTGAGTATagaatgtgtcaaaaca c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 2891252 /Source="Nicolas_upshifts" /id="U2286" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp=1 /psig=0 /xcortree=706 /SigmaFactorBS="tcgcttgagcagctcctggtactaaaaggttgttgctgttac ctgagttattgttaGCCATgtgtctcaCCTCCTTGTGAGTATagaatgtgtcaaaaca c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 2891261..2891275 /Source="Nicolas_upshift_promotors" /id="U2286" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp=1 /psig=0 /xcortree=706 /SigmaFactorBS="tcgcttgagcagctcctggtactaaaaggttgttgctgttac ctgagttattgttaGCCATgtgtctcaCCTCCTTGTGAGTATagaatgtgtcaaaaca c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-10 complement(2891273..2891284) /Source="Nicolas_upshift_promotors" /id="U2287" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=784 /SigmaFactorBS="tcaattttcagctcctgtatacaattaccaaagtttttcTGA ATGAagccatgtgttttgACACATTCTATActcacaaggaggtgagacacatggctaa c" /listShort="sspA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2891284) /Source="Nicolas_upshifts" /id="U2287" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=784 /SigmaFactorBS="tcaattttcagctcctgtatacaattaccaaagtttttcTGA ATGAagccatgtgttttgACACATTCTATActcacaaggaggtgagacacatggctaa c" /listShort="sspA" /GFF_Attribute="listLong" promotor_-35 complement(2891299..2891305) /Source="Nicolas_upshift_promotors" /id="U2287" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=784 /SigmaFactorBS="tcaattttcagctcctgtatacaattaccaaagtttttcTGA ATGAagccatgtgttttgACACATTCTATActcacaaggaggtgagacacatggctaa c" /listShort="sspA" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2891346..2892551) /gene="trmG" /locus_tag="BSU_29580" /old_locus_tag="BSU29580" /EC_number="2.8.1.4" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:10939241, 14757766, 16343540, 22773787, 24705700, 28287455" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10939241, 14757766, 16343540, 22773787, 24705700, 28287455; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="persulfide ATP pyrophosphatase involved in tRNA modification" /protein_id="NP_390836.2" /db_xref="EnsemblGenomes-Gn:BSU29580" /db_xref="EnsemblGenomes-Tr:CAB14936" /db_xref="GOA:O34595" /db_xref="InterPro:IPR003720" /db_xref="InterPro:IPR004114" /db_xref="InterPro:IPR014729" /db_xref="InterPro:IPR020536" /db_xref="SubtiList:BG13827" /db_xref="UniProtKB/Swiss-Prot:O34595" /translation="MNYDHILIRFGEISTKGKNRKSFIERLKQNIRLVLKDYPNLKYF SNRDRMTITLNGEDPEALFPHLKQVFGIQSFSLAIKCDSRLDDIKATALKAIKDQYKP GDTFKVATKRAYKQFELDTNQMNAEIGGHILRNTEGLTVDVRNPDIPLRIEIREEATF LTIRDEKGAGGLPVGSAGKAMLMLSGGFDSPVAGFYAMKRGLSVEAVHFFSPPYTSER AKQKVMDLAKCLSRFGGSMTLHIVPFTKTQELIQKQIPENYTMTATRRLMLQIADRIR EKRNGLAIITGESLGQVASQTLESMYAINAVTSTPILRPLIAMDKTEIIEKSREIGTY ETSIQPFEDCCTIFTPPSPKTRPKKEKIEHFESFVDFEPYIQEAVDNIETMTLYSEQE ANDKFAELF*" gene complement(2891346..2892551) /gene="trmG" /locus_tag="BSU_29580" /old_locus_tag="BSU29580" CDS complement(2892555..2893700) /gene="iscSB" /locus_tag="BSU_29590" /old_locus_tag="BSU29590" /EC_number="2.8.1.7" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:10939241, 11443125, 13129955, 14757766, 16388576, 17237162, 14567704, 22773787, 28882201" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10939241, 11443125, 13129955, 14757766, 16388576, 17237162, 14567704, 22773787, 28882201; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="cysteine desulfurase" /protein_id="NP_390837.1" /db_xref="EnsemblGenomes-Gn:BSU29590" /db_xref="EnsemblGenomes-Tr:CAB14937" /db_xref="GOA:O34874" /db_xref="InterPro:IPR000192" /db_xref="InterPro:IPR015421" /db_xref="InterPro:IPR015422" /db_xref="InterPro:IPR015424" /db_xref="InterPro:IPR016454" /db_xref="SubtiList:BG12632" /db_xref="UniProtKB/Swiss-Prot:O34874" /translation="MIYLDNSSTTKPYDEVLNVYEQTSSRYFGNPSSLHRYGAETEQL LQAAKNQIKRSLGLKKYDIVFTSGATEANNAALKGAALSKIKTGKHIIATSIEHPSVT ESLEQLKELFGFDITYLSVNEDGFVSIEDLKAAIRPDTVLVSMMHVNNEVGSVQPIEA AGEVLKEHSNILFHVDYVQGIYKVPLAIEKAGIDLCSISGHKFHGLKGTGALIVKEGT RLIPLITGGSQQKGIRAGTEHTAGAVSLAKAINLASADFDTRLDTMTAVKELFMNRLS EIEGVVINTPQMNSAPHIINFSVPGIKAEVLLHMLEEQDIFVSTTSACSAKEHKPSKV LLEMGKGEQIAGSSIRISLNYSQTSDVAEPFMNALRPGIKKLREMMR*" gene complement(2892555..2893700) /gene="iscSB" /locus_tag="BSU_29590" /old_locus_tag="BSU29590" S_feature complement(2893701..2894844) /Source="Nicolas_S_feature" /locus_tag="new_3028103_3029246_c" /HighExp="Diami, dia15, dia5, H2O2, G135, G180, G150, C30, Paraq, LBGstat" /AntisenseName="braB" /AntisenseCor="0.41502288403214899" /AntisenseRegPval="-11.9" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.998" /TUlongSig="NA" /TUlongPSig="NA" /label="S1123" promotor_-35 2893787..2893794 /Source="Nicolas_upshift_promotors" /id="U2288" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.741258741258741" /psig=1 /xcortree=2628 /SigmaFactorBS="gttaccataacaaaatttaatagaaaattacgaaaaactagt ATTGACTTctaatttttttaCCATATAATAAGATTTGTTCgtttcgtcatattatctg a" /listShort="S1124, braB" /GFF_Attribute="listLong" /label="promotor_-35" S_feature 2893805..2893894 /Source="Nicolas_S_feature" /locus_tag="new_3028207_3028296" /HighExp="LPh, HPh, BMM, dia0, Heat, G180, Cold, LBGexp, C30, LPhT" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1124" upshifts 2893805 /Source="Nicolas_upshifts" /id="U2288" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.741258741258741" /psig=1 /xcortree=2628 /SigmaFactorBS="gttaccataacaaaatttaatagaaaattacgaaaaactagt ATTGACTTctaatttttttaCCATATAATAAGATTTGTTCgtttcgtcatattatctg a" /listShort="S1124, braB" /GFF_Attribute="listLong" promotor_-10 2893807..2893826 /Source="Nicolas_upshift_promotors" /id="U2288" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.741258741258741" /psig=1 /xcortree=2628 /SigmaFactorBS="gttaccataacaaaatttaatagaaaattacgaaaaactagt ATTGACTTctaatttttttaCCATATAATAAGATTTGTTCgtttcgtcatattatctg a" /listShort="S1124, braB" /GFF_Attribute="listLong" /label="promotor_-10" CDS 2893895..2895232 /gene="braB" /locus_tag="BSU_29600" /old_locus_tag="BSU29600" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:11528000, 15849754, 16850406, 26473603" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11528000, 15849754, 16850406, 26473603; Product type t: transporter" /codon_start=1 /transl_table=11 /product="branched-chain amino acid-Na+ symporter" /protein_id="NP_390838.1" /db_xref="EnsemblGenomes-Gn:BSU29600" /db_xref="EnsemblGenomes-Tr:CAB14938" /db_xref="GOA:O34545" /db_xref="InterPro:IPR004685" /db_xref="SubtiList:BG12573" /db_xref="UniProtKB/Swiss-Prot:O34545" /translation="MKHSLPVKDTIIIGFMLFALFFGAGNMIYPPELGQAAGHNVWKA IGGFLLTGVGLPLLGIIAIALTGKDAKGLADKAHPVFGTIFTVVLYLSIGPLFAIPRT GTVSYEIGAVPFLTGVPERLSLLIFTLIFFGVTYYLALNPSKVVDRVGKILTPIKFTI ILIIVLKAIFTPMGGLGAVTEAYKGTPVFKGFLEGYKTMDALASIVFGVVVVNAVKSK GVTQSKALAAACIKAGVIAALGLTFIYVSLAYLGATSTNAIGPVGEGAKILSASSHYL FGSLGNIVLGAAITVACLTTSIGLVTSCGQYFSKLIPALSYKIVVTIVTLFSLIIANF GLAQIIAFSVPILSAIYPLAIVIIVLSFIDKIFKERREVYIACLIGTGLFSILDGIKA AGFSLGSLDVFLNANLPLYSLGIGWVLPGIVGAVIGYVLTLFIGPSKQLNEIS*" gene 2893895..2895232 /gene="braB" /locus_tag="BSU_29600" /old_locus_tag="BSU29600" promotor_-10 complement(2894830..2894849) /Source="Nicolas_upshift_promotors" /id="U2289" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.949050949050949" /psig="0.998001998001998" /xcortree=1983 /SigmaFactorBS="gcgagtccgaaattcgcaatgatcaagctgaatAACGTGACa atcgtaacgacaaTTTTATATGATAATGCCGGAataagttttgaaaaatattggccgc a" /listShort="S1123, iscS, thiI, sspA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2894844) /Source="Nicolas_upshifts" /id="U2289" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.949050949050949" /psig="0.998001998001998" /xcortree=1983 /SigmaFactorBS="gcgagtccgaaattcgcaatgatcaagctgaatAACGTGACa atcgtaacgacaaTTTTATATGATAATGCCGGAataagttttgaaaaatattggccgc a" /listShort="S1123, iscS, thiI, sspA" /GFF_Attribute="listLong" promotor_-35 complement(2894864..2894871) /Source="Nicolas_upshift_promotors" /id="U2289" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.949050949050949" /psig="0.998001998001998" /xcortree=1983 /SigmaFactorBS="gcgagtccgaaattcgcaatgatcaagctgaatAACGTGACa atcgtaacgacaaTTTTATATGATAATGCCGGAataagttttgaaaaatattggccgc a" /listShort="S1123, iscS, thiI, sspA" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 2895208 /Source="Nicolas_upshifts" /id="D1518" /incds=0 /nref=69 /ntot=174 /MaxReadThrough="1.86149" /MaxDrop="6.26921" /score="14.5905051" /energy="-15.2" /TU="U2288" /idTUdmin="U2288" /TUdmin="-22" /isTUend="TRUE" CDS complement(2895327..2897015) /gene="ezrA" /locus_tag="BSU_29610" /old_locus_tag="BSU29610" /function="16.13: Shape" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:10449747, 15101985, 15317798, 16549676, 17718511, 17873055, 18363795, 19429628, 21401734, 24218584, 25954268, 28357277" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10449747, 15101985, 15317798, 16549676, 17718511, 17873055, 18363795, 19429628, 21401734, 24218584, 25954268, 28357277; Product type r: regulator" /codon_start=1 /transl_table=11 /product="negative regulator of FtsZ ring formation" /protein_id="NP_390839.1" /db_xref="EnsemblGenomes-Gn:BSU29610" /db_xref="EnsemblGenomes-Tr:CAB14939" /db_xref="GOA:O34894" /db_xref="InterPro:IPR010379" /db_xref="PDB:4UXV" /db_xref="SubtiList:BG13934" /db_xref="UniProtKB/Swiss-Prot:O34894" /translation="MEFVIGLLIVLLALFAAGYFFRKKIYAEIDRLESWKIEILNRSI VEEMSKIKHLKMTGQTEEFFEKWREEWDEIVTAHMPKVEELLYDAEENADKYRFKKAN QVLVHIDDLLTAAESSIEKILREISDLVTSEEKSREEIEQVRERYSKSRKNLLAYSHL YGELYDSLEKDLDEIWSGIKQFEEETEGGNYITARKVLLEQDRNLERLQSYIDDVPKL LADCKQTVPGQIAKLKDGYGEMKEKGYKLEHIQLDKELENLSNQLKRAEHVLMTELDI DEASAILQLIDENIQSVYQQLEGEVEAGQSVLSKMPELIIAYDKLKEEKEHTKAETEL VKESYRLTAGELGKQQAFEKRLDEIGKLLSSVKDKLDAEHVAYSLLVEEVASIEKQIE EVKKEHAEYRENLQALRKEELQARETLSNLKKTISETARLLKTSNIPGIPSHIQEMLE NAHHHIQETVNQLNELPLNMEEAGAHLKQAEDIVNRASRESEELVEQVILIEKIIQFG NRFRSQNHILSEQLKEAERRFYAFDYDDSYEIAAAAVEKAAPGAVEKIKADISA*" gene complement(2895327..2897015) /gene="ezrA" /locus_tag="BSU_29610" /old_locus_tag="BSU29610" downshifts complement(2895328) /Source="Nicolas_upshifts" /id="D1519" /incds=0 /nref=224 /ntot=257 /MaxReadThrough="3.34218" /MaxDrop="5.3305" /score="9.25784495" /energy="-8.6" /TU="U2290" /idTUdmin="U2290" /TUdmin="-66" /isTUend="FALSE" S_feature complement(2897016..2897121) /Source="Nicolas_S_feature" /locus_tag="new_3031418_3031523_c" /HighExp="C90, Lbtran, BMM, LBGtran, MG 150, S1, Lbexp, dia0, LBGexp, ferm" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="1, 0.975" /TUlongSig="NA" /TUlongPSig="NA" /label="S1125" promotor_-35 2897098..2897106 /Source="Nicolas_upshift_promotors" /id="U2291" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.985014985014985" /psig=1 /xcortree=2258 /SigmaFactorBS="ttattcagaaagatttcaggatatgtattgagaaaaaCTGTC GTTTtcattgttatTATGATACCATGTAACAAACattttttgaccagaaatcaaaaac t" /listShort="S1126, hisJ, S1129, S1130, S1131, S1132, ytsP" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(2897109..2897128) /Source="Nicolas_upshift_promotors" /id="U2290" /multdbtbs="SigA,SigA" /comp="M4" /sig="SigA" /pcomp="0.57042957042957" /psig=1 /xcortree=2331 /SigmaFactorBS="cctgccgattttgcacaaaaagtttttgatttctgGTCaaaa aatgtttgttaCATGGTATCATAATAACAATgaaaacgacagtttttctcaatacata t" /listShort="S1125, ezrA" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-10 2897117..2897136 /Source="Nicolas_upshift_promotors" /id="U2291" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.985014985014985" /psig=1 /xcortree=2258 /SigmaFactorBS="ttattcagaaagatttcaggatatgtattgagaaaaaCTGTC GTTTtcattgttatTATGATACCATGTAACAAACattttttgaccagaaatcaaaaac t" /listShort="S1126, hisJ, S1129, S1130, S1131, S1132, ytsP" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2897121) /Source="Nicolas_upshifts" /id="U2290" /multdbtbs="SigA,SigA" /comp="M4" /sig="SigA" /pcomp="0.57042957042957" /psig=1 /xcortree=2331 /SigmaFactorBS="cctgccgattttgcacaaaaagtttttgatttctgGTCaaaa aatgtttgttaCATGGTATCATAATAACAATgaaaacgacagtttttctcaatacata t" /listShort="S1125, ezrA" /GFF_Attribute="listLong" upshifts 2897121 /Source="Nicolas_upshifts" /id="U2291" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.985014985014985" /psig=1 /xcortree=2258 /SigmaFactorBS="ttattcagaaagatttcaggatatgtattgagaaaaaCTGTC GTTTtcattgttatTATGATACCATGTAACAAACattttttgaccagaaatcaaaaac t" /listShort="S1126, hisJ, S1129, S1130, S1131, S1132, ytsP" /GFF_Attribute="listLong" S_feature 2897122..2897211 /Source="Nicolas_S_feature" /locus_tag="new_3031524_3031613" /HighExp="HiOs, C90, dia5, T-5.40H, S1, T-3.40H, GM-0.1, GM 15, T3.0H, BC" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1126" S_feature complement(2897123..2897682) /Source="Nicolas_S_feature" /locus_tag="new_3031525_3032084_c" /HighExp="Etha, Salt, Cold, G135, Lbstat, G180, G150, H2O2, Heat, Paraq" /AntisenseName="hisJ" /AntisenseCor="0.37018688255337001" /AntisenseRegPval="-9.4" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.975" /TUlongSig="NA" /TUlongPSig="NA" /label="S1127" promotor_-35 complement(2897144..2897146) /Source="Nicolas_upshift_promotors" /id="U2290" /multdbtbs="SigA,SigA" /comp="M4" /sig="SigA" /pcomp="0.57042957042957" /psig=1 /xcortree=2331 /SigmaFactorBS="cctgccgattttgcacaaaaagtttttgatttctgGTCaaaa aatgtttgttaCATGGTATCATAATAACAATgaaaacgacagtttttctcaatacata t" /listShort="S1125, ezrA" /GFF_Attribute="listLong" /label="promotor_-35" CDS 2897212..2898018 /gene="hisK" /locus_tag="BSU_29620" /old_locus_tag="BSU29620" /EC_number="3.1.3.15" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:10322033" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10322033; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="histidinol phosphate phosphatase" /protein_id="NP_390840.1" /db_xref="EnsemblGenomes-Gn:BSU29620" /db_xref="EnsemblGenomes-Tr:CAB14940" /db_xref="GOA:O34411" /db_xref="InterPro:IPR004013" /db_xref="InterPro:IPR010140" /db_xref="InterPro:IPR016195" /db_xref="SubtiList:BG13931" /db_xref="UniProtKB/Swiss-Prot:O34411" /translation="MQKRDGHIHTPFCPHGSNDTLRQYAEEALKKGFESITFTEHAPL PPSFTDPTPLKDSAMAQASLERYIHEISGLKKEYRGQLSIRTGLEVDYIAEFEDEITL FLDTYGPYLDDSILSVHFLRTDSSYLCLDYDEHTFKELISACGSIEAVYEQYYRSIYS SIVASLGVYKPKRVGHITLVQKFIKLFPYSMSEHIRGLVSLCLNAIEENGMELDFNTS GLRKTYAGGIYIEDWMLNEAKQKKIPLVFGSDAHQAGDVGYAYEAFLERC*" gene 2897212..2898018 /gene="hisK" /locus_tag="BSU_29620" /old_locus_tag="BSU29620" promotor_-10 complement(2897686..2897705) /Source="Nicolas_upshift_promotors" /id="U2292" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.92007992007992" /psig="0.975024975024975" /xcortree=92 /SigmaFactorBS="aatttttggacgagtgtgatgtgaccgactcttttTGGCTTA TaaacgccgagaGATGCTACAATGGAAGAATAgatactccggtaatattgttcatata c" /listShort="S1127, S1125, ezrA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2897699) /Source="Nicolas_upshifts" /id="U2292" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.92007992007992" /psig="0.975024975024975" /xcortree=92 /SigmaFactorBS="aatttttggacgagtgtgatgtgaccgactcttttTGGCTTA TaaacgccgagaGATGCTACAATGGAAGAATAgatactccggtaatattgttcatata c" /listShort="S1127, S1125, ezrA" /GFF_Attribute="listLong" promotor_-35 complement(2897717..2897724) /Source="Nicolas_upshift_promotors" /id="U2292" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.92007992007992" /psig="0.975024975024975" /xcortree=92 /SigmaFactorBS="aatttttggacgagtgtgatgtgaccgactcttttTGGCTTA TaaacgccgagaGATGCTACAATGGAAGAATAgatactccggtaatattgttcatata c" /listShort="S1127, S1125, ezrA" /GFF_Attribute="listLong" /label="promotor_-35" S_feature complement(2897968..2898014) /Source="Nicolas_S_feature" /locus_tag="new_3032370_3032416_c" /HighExp="M9-stat, T5.0H, LoTm, T4.0H, S2, BC, T3.30H, S4, T3.0H, B60" /AntisenseName="hisJ" /AntisenseCor="-0.46006853678527698" /AntisenseRegPval="-14.8" /CDS_PredictionProba="NA" /TUshortSig="NA" /TUshortPSig="NA" /TUlongSig="NA" /TUlongPSig="NA" /label="S1128" downshifts complement(2897990) /Source="Nicolas_upshifts" /id="D1520" /incds=0 /nref=51 /ntot=97 /MaxReadThrough="1.55523" /MaxDrop="6.84653" /score="-4.34170655" /energy="-10.5" /TU="NA" /idTUdmin="U2296" /TUdmin=0 /isTUend="TRUE" CDS complement(2898015..2898638) /gene="refZ" /locus_tag="BSU_29630" /old_locus_tag="BSU29630" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:11988534, 22730127, 26360512" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11988534, 22730127, 26360512; Product type r: regulator" /codon_start=1 /transl_table=11 /product="regulator of FtsZ defining the chromosome regioncaptured in the forespore" /protein_id="NP_390841.1" /db_xref="EnsemblGenomes-Gn:BSU29630" /db_xref="EnsemblGenomes-Tr:CAB14941" /db_xref="GOA:O34970" /db_xref="InterPro:IPR001647" /db_xref="InterPro:IPR009057" /db_xref="InterPro:IPR023772" /db_xref="SubtiList:BG13927" /db_xref="UniProtKB/Swiss-Prot:O34970" /translation="MKVSTKDKIIESAVMLFNQKGFSGTSVREIAKSADVNVAHISYY FKGKGGLMEHLVSEFYEGYSKTLETAASNISTQSTQEQLLQLVFDILSYQHNHRQLTR FVYREVTIDSTLIREIMSTYLMKEKYIFQLIIEEGEKQREYLTLPLPHFILQLKSLLM MPYLQPQYISEVLYMQPHEPYFYKMYFEEIKIWIRSVFRTGDVALTN*" gene complement(2898015..2898638) /gene="refZ" /locus_tag="BSU_29630" /old_locus_tag="BSU29630" S_feature 2898019..2898361 /Source="Nicolas_S_feature" /locus_tag="new_3032421_3032763" /HighExp="C90, HiOs, Sw, dia5, GM-0.1, S1, MG 5, UNK1, MG 60, MG t5" /AntisenseName="yttP" /AntisenseCor="-0.79169109805002003" /AntisenseRegPval="-58.4" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1129" promotor_-35 2898339..2898346 /Source="Nicolas_upshift_promotors" /id="U2293" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.98901098901099" /psig="0.999000999001" /xcortree=2053 /SigmaFactorBS="ggagtcaattgtgacttcccggtagacaaaacgagtTAATTG ACgatgattatgctgaTAGGATAAAATATCGAAAACcaattgaagaagctgttcctgc g" /listShort="S1130, S1131, S1132, ytsP" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2898361..2898380 /Source="Nicolas_upshift_promotors" /id="U2293" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.98901098901099" /psig="0.999000999001" /xcortree=2053 /SigmaFactorBS="ggagtcaattgtgacttcccggtagacaaaacgagtTAATTG ACgatgattatgctgaTAGGATAAAATATCGAAAACcaattgaagaagctgttcctgc g" /listShort="S1130, S1131, S1132, ytsP" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 2898363..2898506 /Source="Nicolas_S_feature" /locus_tag="new_3032765_3032908" /HighExp="Diami, dia15, dia5, H2O2, C90, Paraq, Salt, Etha, Oxctl, Sw" /AntisenseName="yttP" /AntisenseCor="-0.81457903975257295" /AntisenseRegPval="-64.400000000000006" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="0.999, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S1130" upshifts 2898363 /Source="Nicolas_upshifts" /id="U2293" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.98901098901099" /psig="0.999000999001" /xcortree=2053 /SigmaFactorBS="ggagtcaattgtgacttcccggtagacaaaacgagtTAATTG ACgatgattatgctgaTAGGATAAAATATCGAAAACcaattgaagaagctgttcctgc g" /listShort="S1130, S1131, S1132, ytsP" /GFF_Attribute="listLong" promotor_-35 2898478..2898482 /Source="Nicolas_upshift_promotors" /id="U2294" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.322677322677323" /psig="0.982017982017982" /xcortree=2757 /SigmaFactorBS="ctgtagccttcgtaaaactctgaaactaagTGTTCcatcaag cctcctttGCCTTTAAAATAGTAGGAGAtgtgcgcaacatttacatcagctgactttg c" /listShort="S1131, S1132, ytsP" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2898498..2898517 /Source="Nicolas_upshift_promotors" /id="U2294" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.322677322677323" /psig="0.982017982017982" /xcortree=2757 /SigmaFactorBS="ctgtagccttcgtaaaactctgaaactaagTGTTCcatcaag cctcctttGCCTTTAAAATAGTAGGAGAtgtgcgcaacatttacatcagctgactttg c" /listShort="S1131, S1132, ytsP" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 2898508..2898638 /Source="Nicolas_S_feature" /locus_tag="new_3032910_3033040" /HighExp="Diami, dia15, dia5, H2O2, Paraq, C90, HPh, LBGexp, Oxctl, Sw" /AntisenseName="yttP" /AntisenseCor="-0.82273476313537297" /AntisenseRegPval="-66.7" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA, SigA" /TUshortPSig="0.982, 0.999, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S1131" upshifts 2898508 /Source="Nicolas_upshifts" /id="U2294" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.322677322677323" /psig="0.982017982017982" /xcortree=2757 /SigmaFactorBS="ctgtagccttcgtaaaactctgaaactaagTGTTCcatcaag cctcctttGCCTTTAAAATAGTAGGAGAtgtgcgcaacatttacatcagctgactttg c" /listShort="S1131, S1132, ytsP" /GFF_Attribute="listLong" S_feature 2898640..2898764 /Source="Nicolas_S_feature" /locus_tag="new_3033042_3033166" /HighExp="Diami, dia5, dia15, H2O2, C90, BC, HiOs, Paraq, Sw, HPh" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA, SigA, SigA" /TUshortPSig="0.598, 0.982, 0.999, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S1132" upshifts 2898640 /Source="Nicolas_upshifts" /id="U2295" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.582417582417582" /psig="0.598401598401598" /xcortree=570 /SigmaFactorBS="ttttggttaaaaagcatgacagcagattcaataattttgtct ttggtgcttactttcatacggctcactccttcctCTTGATACTATTCAAGCAGAaagc c" /listShort="S1132, ytsP" /GFF_Attribute="listLong" promotor_-10 complement(2898654..2898672) /Source="Nicolas_upshift_promotors" /id="U2296" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=448 /SigmaFactorBS="aaagttccggcttttctgccggcatttgtcgataagttcttA CAGGAACAgcggctttctGCTTGAATAGTATCAAGAGgaaggagtgagccgtatgaaa g" /listShort="yttP" /GFF_Attribute="listLong" /label="promotor_-10" misc_feature 2898656..2898675 /Source="Nicolas_upshift_promotors" /id="U2295" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.582417582417582" /psig="0.598401598401598" /xcortree=570 /SigmaFactorBS="ttttggttaaaaagcatgacagcagattcaataattttgtct ttggtgcttactttcatacggctcactccttcctCTTGATACTATTCAAGCAGAaagc c" /listShort="S1132, ytsP" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(2898672) /Source="Nicolas_upshifts" /id="U2296" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=448 /SigmaFactorBS="aaagttccggcttttctgccggcatttgtcgataagttcttA CAGGAACAgcggctttctGCTTGAATAGTATCAAGAGgaaggagtgagccgtatgaaa g" /listShort="yttP" /GFF_Attribute="listLong" promotor_-35 complement(2898683..2898691) /Source="Nicolas_upshift_promotors" /id="U2296" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=448 /SigmaFactorBS="aaagttccggcttttctgccggcatttgtcgataagttcttA CAGGAACAgcggctttctGCTTGAATAGTATCAAGAGgaaggagtgagccgtatgaaa g" /listShort="yttP" /GFF_Attribute="listLong" /label="promotor_-35" CDS 2898765..2899256 /gene="msrC" /locus_tag="BSU_29640" /old_locus_tag="BSU29640" /EC_number="1.8.4.14" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 17535911, 28032445; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="free methionine-(R)-sulfoxide reductase" /protein_id="NP_390842.2" /db_xref="EnsemblGenomes-Gn:BSU29640" /db_xref="EnsemblGenomes-Tr:CAB14942" /db_xref="InterPro:IPR000614" /db_xref="InterPro:IPR003018" /db_xref="InterPro:IPR029016" /db_xref="SubtiList:BG13923" /db_xref="UniProtKB/Swiss-Prot:O34553" /translation="MFHVEKQSGDKEKDYQLLLKQLEAMTEDETDQIANYANASALLY HSLPEVNWAGFYFAKEEDGQLVLGPFQGLPACVRIPFGRGVCGTAYANGKVERIEDVN AFPGHIACDAASQSEIVLPIRVDGKIVGVLDIDSPVKNRFDEIDEKYLTQFAETLEKA LAQ*" gene 2898765..2899256 /gene="msrC" /locus_tag="BSU_29640" /old_locus_tag="BSU29640" downshifts 2899235 /Source="Nicolas_upshifts" /id="D1521" /incds=0 /nref=72 /ntot=213 /MaxReadThrough="3.66093" /MaxDrop="6.50628" /score="34.0123402" /energy="-11.9" /TU="U2291,U2293,U2294" /idTUdmin="U2295" /TUdmin=0 /isTUend="TRUE" CDS complement(2899294..2901033) /gene="dgcP" /locus_tag="BSU_29650" /old_locus_tag="BSU29650" /EC_number="2.7.7.65" /function="16.12: Sense" /function="16.3: Control" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:23893111" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 23893111; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="diguanylate cyclase" /protein_id="NP_390843.1" /db_xref="EnsemblGenomes-Gn:BSU29650" /db_xref="EnsemblGenomes-Tr:CAB14943" /db_xref="InterPro:IPR000160" /db_xref="InterPro:IPR029016" /db_xref="InterPro:IPR029787" /db_xref="SubtiList:BG13918" /db_xref="UniProtKB/Swiss-Prot:O34325" /translation="MVEQTKDQLSAFHYHMLDFLLTKSEKVTFTDSFIWLTSAIQTYF STLCVSLTPSPSDFVTKLADGEARFSASKINASCYLIEDGSGRRFHLACRQDEEIPEG LPDVVASFLNQSMKQERLYNKTIYQKKIYKMTELFHSLLDQTDVLKQLLESLTSTFSL FEFSLFISHDQDQCLGIPAKELYMEGEKSDSFALKVYLSGDILRKNESVAYIPIKGQQ GTYGVLKAEGTGDSFLTDACLDEMSLLANAAGKAFENAQLYEQSKASIANLELINETS RRLNQRLTLTDTMNDLAVRMAESFQAEEVGFFHIDHFENLTLLPGSTAFFKEAKPSDF YNELKEKLYEGEKGVFIGNGQSVFGKAGYGSLMAAPMIQNDRLLGFAVLLKQELYAFT FEMYKLFQALIHHATLAVTNSMLRDRLEHLVKTDQLTELYSRAYLDEKIQYSMKIHQK GVFILVDIDNFKNVNDTYGHQTGDEILIQVASVIKSNIRKHDVGARWGGEELAIYLPN VPVAVGKRITERLVYAVRKNTKPEVTISCGISCWTTETKKSLKELVHEADEALYSAKR SGKNRLMIHDSIK*" gene complement(2899294..2901033) /gene="dgcP" /locus_tag="BSU_29650" /old_locus_tag="BSU29650" downshifts complement(2899312) /Source="Nicolas_upshifts" /id="D1522" /incds=0 /nref=23 /ntot=178 /MaxReadThrough="3.68958" /MaxDrop="4.52201" /score="-0.637788006" /energy="-11.9" /TU="U2298" /idTUdmin="U2298" /TUdmin="-45" /isTUend="FALSE" promotor_-35 2900507..2900514 /Source="Nicolas_upshift_promotors" /id="U2297" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2821 /SigmaFactorBS="ttttccccttccatatacagctcttttgcaggaatcCCTAAA CAttggtcttgatcgTGCGATATAAATAAAGAAAactcaaaaagagaaaatgtgcttg t" /listShort="S1133, S1135, rpsD" /listLong="S1137" /label="promotor_-35" promotor_-10 2900528..2900546 /Source="Nicolas_upshift_promotors" /id="U2297" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2821 /SigmaFactorBS="ttttccccttccatatacagctcttttgcaggaatcCCTAAA CAttggtcttgatcgTGCGATATAAATAAAGAAAactcaaaaagagaaaatgtgcttg t" /listShort="S1133, S1135, rpsD" /listLong="S1137" /label="promotor_-10" upshifts 2900531 /Source="Nicolas_upshifts" /id="U2297" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2821 /SigmaFactorBS="ttttccccttccatatacagctcttttgcaggaatcCCTAAA CAttggtcttgatcgTGCGATATAAATAAAGAAAactcaaaaagagaaaatgtgcttg t" /listShort="S1133, S1135, rpsD" /listLong="S1137" S_feature 2900533..2901128 /Source="Nicolas_S_feature" /locus_tag="new_3034935_3035530" /HighExp="Cold, LBGstat, C30, Lbstat, GM 25, GM 10, GM 120, GM-0.1, GM 5, GM-0.2" /AntisenseName="ytrP" /AntisenseCor="-0.113221814489707" /AntisenseRegPval="-1.2" /CDS_PredictionProba="NA" /TUshortSig="SigD" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1133" misc_feature complement(2901063..2901082) /Source="Nicolas_upshift_promotors" /id="U2298" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.897102897102897" /psig="0.999000999001" /xcortree=428 /SigmaFactorBS="aatttatttgttttgaagtcaaccattcctccattattgctt caccgttTATGATATAATAAACAAAAAttagtggtaaacttttaggtgataaaaacat g" /listShort="ytrP" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(2901071) /Source="Nicolas_upshifts" /id="U2298" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.897102897102897" /psig="0.999000999001" /xcortree=428 /SigmaFactorBS="aatttatttgttttgaagtcaaccattcctccattattgctt caccgttTATGATATAATAAACAAAAAttagtggtaaacttttaggtgataaaaacat g" /listShort="ytrP" /GFF_Attribute="listLong" S_feature complement(2901073..2901906) /Source="Nicolas_S_feature" /locus_tag="new_3035475_3036308_c" /HighExp="Etha, S7, Gly, S8, M9-stat, Sw, G135, S6, BC, C30" /AntisenseName="rpsD" /AntisenseCor="-0.48019282175486899" /AntisenseRegPval="-16.2" /CDS_PredictionProba="NA" /TUshortSig="SigB" /TUshortPSig="0.965" /TUlongSig="NA" /TUlongPSig="NA" /label="S1134" promotor_-35 2901109..2901116 /Source="Nicolas_upshift_promotors" /id="U2299" /multdbtbs="SigA" /comp="M17" /sig="SigA" /pcomp="0.837162837162837" /psig=1 /xcortree=2658 /SigmaFactorBS="ttattatatcataaacggtgaagcaataatggaggaatgGTT GACTTcaaaacaaataaaTTATATAATGACCTTTGTGTgaaatattgcagcctttttg t" /listShort="S1135, rpsD, S1137" /GFF_Attribute="listLong" /label="promotor_-35" S_feature 2901130..2901327 /Source="Nicolas_S_feature" /locus_tag="new_3035532_3035729" /HighExp="UNK1, Cold, HPh, C30, aero, LPhT, MG 25, Oxctl, Heat, GM 60" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.139124" /TUshortSig="SigA, SigD" /TUshortPSig="1, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S1135" promotor_-10 2901130..2901149 /Source="Nicolas_upshift_promotors" /id="U2299" /multdbtbs="SigA" /comp="M17" /sig="SigA" /pcomp="0.837162837162837" /psig=1 /xcortree=2658 /SigmaFactorBS="ttattatatcataaacggtgaagcaataatggaggaatgGTT GACTTcaaaacaaataaaTTATATAATGACCTTTGTGTgaaatattgcagcctttttg t" /listShort="S1135, rpsD, S1137" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2901130 /Source="Nicolas_upshifts" /id="U2299" /multdbtbs="SigA" /comp="M17" /sig="SigA" /pcomp="0.837162837162837" /psig=1 /xcortree=2658 /SigmaFactorBS="ttattatatcataaacggtgaagcaataatggaggaatgGTT GACTTcaaaacaaataaaTTATATAATGACCTTTGTGTgaaatattgcagcctttttg t" /listShort="S1135, rpsD, S1137" /GFF_Attribute="listLong" misc_RNA 2901187..2901319 /gene="ldsD" /locus_tag="BSU_misc_RNA_93" /product="ribosomal protein S4 leader mRNA sequence" /experiment="publication(s) with functional evidences, PMID:23611891" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 23611891" gene 2901187..2901319 /gene="ldsD" /locus_tag="BSU_misc_RNA_93" CDS 2901328..2901930 /gene="rpsD" /locus_tag="BSU_29660" /old_locus_tag="BSU29660" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:1400226, 1699930, 1906866, 12682299, 23611891" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1400226, 1699930, 1906866, 12682299, 23611891; Product type s: structure" /codon_start=1 /transl_table=11 /product="ribosomal protein S4 (BS4)" /protein_id="NP_390844.1" /db_xref="EnsemblGenomes-Gn:BSU29660" /db_xref="EnsemblGenomes-Tr:CAB14944" /db_xref="GOA:P21466" /db_xref="InterPro:IPR001912" /db_xref="InterPro:IPR002942" /db_xref="InterPro:IPR005709" /db_xref="InterPro:IPR018079" /db_xref="InterPro:IPR022801" /db_xref="InterPro:IPR036986" /db_xref="PDB:3J9W" /db_xref="PDB:5NJT" /db_xref="SubtiList:BG10372" /db_xref="UniProtKB/Swiss-Prot:P21466" /translation="MARYTGPSWKLSRRLGISLSGTGKELEKRPYAPGPHGPGQRKKL SEYGLQLQEKQKLRHMYGVNERQFRTLFDKAGKLAGKHGENFMILLDSRLDNVVYKLG LARTRRQARQLVNHGHILVDGSRVDIPSYLVKPGQTIGVREKSRNLSIIKESVEVNNF VPEYLTFDAEKLEGTFTRLPERSELAPEINEALIVEFYSR*" gene 2901328..2901930 /gene="rpsD" /locus_tag="BSU_29660" /old_locus_tag="BSU29660" downshifts 2901853 /Source="Nicolas_upshifts" /id="D1523" /incds=1 /nref=1 /ntot=106 /MaxReadThrough="8.1141" /MaxDrop="2.9392" /score="31.6842" /energy="-13.6" /TU="U2297,U2299" /idTUdmin="U2297" /TUdmin="-44" /isTUend="FALSE" S_feature complement(2901908..2902127) /Source="Nicolas_S_feature" /locus_tag="new_3036310_3036529_c" /HighExp="S5, Etha, S8, S6, S7, S4, BT, S3, M9-stat, B36" /AntisenseName="rpsD" /AntisenseCor="-0.59018291599064199" /AntisenseRegPval="-25.9" /CDS_PredictionProba="0.99997899999999995" /TUshortSig="SigB" /TUshortPSig="0.965" /TUlongSig="NA" /TUlongPSig="NA" /label="S1136" downshifts 2901916 /Source="Nicolas_upshifts" /id="D1524" /incds=0 /nref=135 /ntot=252 /MaxReadThrough="5.6866" /MaxDrop="6.10502" /score="31.6842" /energy="-13.6" /TU="U2299" /idTUdmin="U2297" /TUdmin=19 /isTUend="TRUE" downshifts complement(2901951) /Source="Nicolas_upshifts" /id="D1525" /incds=0 /nref=1 /ntot=23 /MaxReadThrough="4.84346" /MaxDrop="3.28594" /score="-4.07107651" /energy="-10.8" /TU="U2300" /idTUdmin="U2301" /TUdmin=264 /isTUend="FALSE" downshifts 2901963 /Source="Nicolas_upshifts" /id="D1526" /incds=0 /nref=1 /ntot=28 /MaxReadThrough="5.7799" /MaxDrop="4.26349" /score="31.6842" /energy="-13.6" /TU="U2299" /idTUdmin="U2297" /TUdmin=66 /isTUend="FALSE" S_feature 2902008..2902181 /Source="Nicolas_S_feature" /locus_tag="new_3036410_3036583" /HighExp="LBGtran, LoTm, C30, Cold, LBGexp, B60, dia15, B36, H2O2, BT" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="SigD" /TUlongPSig=1 /label="S1137" promotor_-10 complement(2902123..2902141) /Source="Nicolas_upshift_promotors" /id="U2300" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.965034965034965" /psig="0.965034965034965" /xcortree=732 /SigmaFactorBS="agatcctttgccactgaaggcaaaggatcttttTGTTTACcg cataggaatgaaAGGAAAAGAGTATATTAGAtagggcaaacacgaccaatcaccacct t" /listShort="S1136, S1134, ytrP" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2902135) /Source="Nicolas_upshifts" /id="U2300" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.965034965034965" /psig="0.965034965034965" /xcortree=732 /SigmaFactorBS="agatcctttgccactgaaggcaaaggatcttttTGTTTACcg cataggaatgaaAGGAAAAGAGTATATTAGAtagggcaaacacgaccaatcaccacct t" /listShort="S1136, S1134, ytrP" /GFF_Attribute="listLong" downshifts 2902139 /Source="Nicolas_upshifts" /id="D1527" /incds=0 /nref=7 /ntot=151 /MaxReadThrough="1.39547" /MaxDrop="6.12149" /score="26.4940291" /energy="-16.4" /TU="NA" /idTUdmin="U2299" /TUdmin=0 /isTUend="TRUE" promotor_-35 complement(2902156..2902162) /Source="Nicolas_upshift_promotors" /id="U2300" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.965034965034965" /psig="0.965034965034965" /xcortree=732 /SigmaFactorBS="agatcctttgccactgaaggcaaaggatcttttTGTTTACcg cataggaatgaaAGGAAAAGAGTATATTAGAtagggcaaacacgaccaatcaccacct t" /listShort="S1136, S1134, ytrP" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2902201..2903469) /gene="tyrS" /locus_tag="BSU_29670" /old_locus_tag="BSU29670" /EC_number="6.1.1.1" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:12547201, 15879350, 1735721, 9098057" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12547201, 15879350, 1735721, 9098057; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="tyrosyl-tRNA synthetase" /protein_id="NP_390845.1" /db_xref="EnsemblGenomes-Gn:BSU29670" /db_xref="EnsemblGenomes-Tr:CAB14945" /db_xref="GOA:P22326" /db_xref="InterPro:IPR001412" /db_xref="InterPro:IPR002305" /db_xref="InterPro:IPR002307" /db_xref="InterPro:IPR002942" /db_xref="InterPro:IPR014729" /db_xref="InterPro:IPR024088" /db_xref="InterPro:IPR024107" /db_xref="InterPro:IPR036986" /db_xref="SubtiList:BG10371" /db_xref="UniProtKB/Swiss-Prot:P22326" /translation="MTNLLEDLSFRGLIQQMTDEEGLNKQLNEEKIRLYSGFDPTADS LHIGHLLPILTLRRFQLAGHHPIALVGGATGLIGDPSGKKAERTLNTADIVSEWSQKI KNQLSRFLDFEAAENPAVIANNFDWIGKMNVIDFLRDVGKNFGINYMLAKDTVSSRIE SGISYTEFSYMILQSYDFLNLYRDKNCKLQIGGSDQWGNITAGLELIRKSEEEGAKAF GLTIPLVTKADGTKFGKTEGGAIWLDKEKTSPYEFYQFWINTDDRDVVKYLKYFTFLS KEEIEAYAEKTETAPEKREAQKRLAEEVTSLVHGREALEQAINISQALFSGNIKELSA QDVKVGFKDVPSMEVDSTQELSLVDVLVQSKLSPSKRQAREDIQNGAVYINGERQTEI NYTLSGEDRIENQFTVLRRGKKKYFLVTYK*" gene complement(2902201..2903469) /gene="tyrS" /locus_tag="BSU_29670" /old_locus_tag="BSU29670" downshifts complement(2902227) /Source="Nicolas_upshifts" /id="D1528" /incds=0 /nref=110 /ntot=357 /MaxReadThrough="2.2673" /MaxDrop="6.847" /score="22.5238672" /energy="-16.4" /TU="NA" /idTUdmin="U2301" /TUdmin="-12" /isTUend="TRUE" misc_RNA complement(2903493..2903766) /gene="tboY" /locus_tag="BSU_misc_RNA_83" /product="T-Box riboswitch specific of tyrosine tRNA ligase" /experiment="publication(s) with functional evidences, PMID:8045882, 10943892, 1317842, 9098041, 12165569, 12547201" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8045882, 10943892, 1317842, 9098041, 12165569, 12547201; Product type n : RNA" /function="16.3: Control" gene complement(2903493..2903766) /gene="tboY" /locus_tag="BSU_misc_RNA_83" S_feature complement(2903514..2903657) /Source="Nicolas_S_feature" /locus_tag="new_3037916_3038059_c" /HighExp="B60, Sw, B36, BC, M9-stat, T1.30H, S4, T4.0H, T2.30H, S7" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.40126600000000001" /TUshortSig="SigA, SigA" /TUshortPSig="0.998, 0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S1138" downshifts complement(2903557) /Source="Nicolas_upshifts" /id="D1529" /incds=0 /nref=58 /ntot=127 /MaxReadThrough="6.75235" /MaxDrop="6.49727" /score="45.7279775" /energy="-17.7" /TU="U2301,U2303" /idTUdmin="U2301" /TUdmin="-1342" /isTUend="FALSE" promotor_-10 complement(2903764..2903783) /Source="Nicolas_upshift_promotors" /id="U2301" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.587412587412587" /psig="0.998001998001998" /xcortree=599 /SigmaFactorBS="gagatctgtcaacaatggaggattaaaaggcggCGTTGACAc aggattttattTATGTTAAAAATGATATAGCttcatatgaaaaggtaaagattgagac a" /listShort="ytzK, S1138, tyrS" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2903776) /Source="Nicolas_upshifts" /id="U2301" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.587412587412587" /psig="0.998001998001998" /xcortree=599 /SigmaFactorBS="gagatctgtcaacaatggaggattaaaaggcggCGTTGACAc aggattttattTATGTTAAAAATGATATAGCttcatatgaaaaggtaaagattgagac a" /listShort="ytzK, S1138, tyrS" /GFF_Attribute="listLong" promotor_-35 complement(2903796..2903803) /Source="Nicolas_upshift_promotors" /id="U2301" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.587412587412587" /psig="0.998001998001998" /xcortree=599 /SigmaFactorBS="gagatctgtcaacaatggaggattaaaaggcggCGTTGACAc aggattttattTATGTTAAAAATGATATAGCttcatatgaaaaggtaaagattgagac a" /listShort="ytzK, S1138, tyrS" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2903811..2905529) /gene="acsA" /locus_tag="BSU_29680" /old_locus_tag="BSU29680" /EC_number="6.2.1.1" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:7934817, 10986270, 11255012, 16855235, 18487328" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7934817, 10986270, 11255012, 16855235, 18487328; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="acetyl-CoA synthetase" /protein_id="NP_390846.1" /db_xref="EnsemblGenomes-Gn:BSU29680" /db_xref="EnsemblGenomes-Tr:CAB14946" /db_xref="GOA:P39062" /db_xref="InterPro:IPR000873" /db_xref="InterPro:IPR020845" /db_xref="InterPro:IPR025110" /db_xref="SubtiList:BG10370" /db_xref="UniProtKB/Swiss-Prot:P39062" /translation="MNLKALPAIEGDHNLKNYEETYRHFDWAEAEKHFSWHETGKLNA AYEAIDRHAESFRKNKVALYYKDAKRDEKYTFKEMKEESNRAGNVLRRYGNVEKGDRV FIFMPRSPELYFIMLGAIKIGAIAGPLFEAFMEGAVKDRLENSEAKVVVTTPELLERI PVDKLPHLQHVFVVGGEAESGTNIINYDEAAKQESTRLDIEWMDKKDGFLLHYTSGST GTPKGVLHVHEAMIQQYQTGKWVLDLKEEDIYWCTADPGWVTGTVYGIFAPWLNGATN VIVGGRFSPESWYGTIEQLGVNVWYSAPTAFRMLMGAGDEMAAKYDLTSLRHVLSVGE PLNPEVIRWGHKVFNKRIHDTWWMTETGSQLICNYPCMDIKPGSMGKPIPGVEAAIVD NQGNELPPYRMGNLAIKKGWPSMMHTIWNNPEKYESYFMPGGWYVSGDSAYMDEEGYF WFQGRVDDVIMTSGERVGPFEVESKLVEHPAIAEAGVIGKPDPVRGEIIKAFIALREG FEPSDKLKEEIRLFVKQGLAAHAAPREIEFKDKLPKTRSGKIMRRVLKAWELNLPAGD LSTMED*" gene complement(2903811..2905529) /gene="acsA" /locus_tag="BSU_29680" /old_locus_tag="BSU29680" promotor_-35 2905543..2905550 /Source="Nicolas_upshift_promotors" /id="U2302" /multdbtbs="-" /comp="M18" /sig="SigA" /pcomp="0.355644355644356" /psig="0.63936063936064" /xcortree=379 /SigmaFactorBS="gtaacgctttcaagttcatgcccaaacatcccCCTTTGCTga agttgtcacaatTATTATAGTATATATTCATAttcttctcaatttttaaaatataaac c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(2905557..2905576) /Source="Nicolas_upshift_promotors" /id="U2303" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.48051948051948" /psig="0.999000999001" /xcortree=357 /SigmaFactorBS="aataccaaattataaagcgttttcaacatggtttatatttta aaAATTGAGaagaatatgaataTATACTATAATAATTGTGACaacttcagcaaagggg g" /listShort="acsA, ytzK, S1138, tyrS" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-10 2905565..2905584 /Source="Nicolas_upshift_promotors" /id="U2302" /multdbtbs="-" /comp="M18" /sig="SigA" /pcomp="0.355644355644356" /psig="0.63936063936064" /xcortree=379 /SigmaFactorBS="gtaacgctttcaagttcatgcccaaacatcccCCTTTGCTga agttgtcacaatTATTATAGTATATATTCATAttcttctcaatttttaaaatataaac c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2905571 /Source="Nicolas_upshifts" /id="U2302" /multdbtbs="-" /comp="M18" /sig="SigA" /pcomp="0.355644355644356" /psig="0.63936063936064" /xcortree=379 /SigmaFactorBS="gtaacgctttcaagttcatgcccaaacatcccCCTTTGCTga agttgtcacaatTATTATAGTATATATTCATAttcttctcaatttttaaaatataaac c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" upshifts complement(2905580) /Source="Nicolas_upshifts" /id="U2303" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.48051948051948" /psig="0.999000999001" /xcortree=357 /SigmaFactorBS="aataccaaattataaagcgttttcaacatggtttatatttta aaAATTGAGaagaatatgaataTATACTATAATAATTGTGACaacttcagcaaagggg g" /listShort="acsA, ytzK, S1138, tyrS" /GFF_Attribute="listLong" promotor_-35 complement(2905590..2905596) /Source="Nicolas_upshift_promotors" /id="U2303" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.48051948051948" /psig="0.999000999001" /xcortree=357 /SigmaFactorBS="aataccaaattataaagcgttttcaacatggtttatatttta aaAATTGAGaagaatatgaataTATACTATAATAATTGTGACaacttcagcaaagggg g" /listShort="acsA, ytzK, S1138, tyrS" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 2905613..2905620 /Source="Nicolas_upshift_promotors" /id="U2304" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.615384615384615" /psig="0.993006993006993" /xcortree=496 /SigmaFactorBS="tattcatattcttctcaatttttaaaatataaaccaTGTTGA AAacgctttataattTGGTATTCTTAAAGAAGGCAtgtatttttgataagaattgatg g" /listShort="acuA, acuB, acuC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2905634..2905653 /Source="Nicolas_upshift_promotors" /id="U2304" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.615384615384615" /psig="0.993006993006993" /xcortree=496 /SigmaFactorBS="tattcatattcttctcaatttttaaaatataaaccaTGTTGA AAacgctttataattTGGTATTCTTAAAGAAGGCAtgtatttttgataagaattgatg g" /listShort="acuA, acuB, acuC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2905637 /Source="Nicolas_upshifts" /id="U2304" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.615384615384615" /psig="0.993006993006993" /xcortree=496 /SigmaFactorBS="tattcatattcttctcaatttttaaaatataaaccaTGTTGA AAacgctttataattTGGTATTCTTAAAGAAGGCAtgtatttttgataagaattgatg g" /listShort="acuA, acuB, acuC" /GFF_Attribute="listLong" CDS 2905690..2906322 /gene="acuA" /locus_tag="BSU_29690" /old_locus_tag="BSU29690" /EC_number="2.3.1.-" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:7934817, 10368162, 10809684, 11274109, 16855235, 18487328, 19136592, 24957627" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7934817, 10368162, 10809684, 11274109, 16855235, 18487328, 19136592, 24957627; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="protein acetyltransferase (acetylates AcsA)" /protein_id="NP_390847.1" /db_xref="EnsemblGenomes-Gn:BSU29690" /db_xref="EnsemblGenomes-Tr:CAB14947" /db_xref="GOA:P39065" /db_xref="InterPro:IPR000182" /db_xref="InterPro:IPR016181" /db_xref="InterPro:IPR024699" /db_xref="SubtiList:BG10369" /db_xref="UniProtKB/Swiss-Prot:P39065" /translation="MEHHKTYHSANIKTATGSLLIEGPVSPEDLAGYEFHKDLTAFRP PREQHEALVDIAGLPEGRIIIARDGRTIVGYVTYLYPDPLERWSEGNMEDLIELGAIE VAPDYRGCAVGKTLLTVSMMDEQMENYIVMTTEYYWHWDLKGMKKDVWEYRKIMEKMM NAGGLVWFATDEPEISSHPANCLMARIGKNVSQESIEQFDRLRFYHRYMY*" gene 2905690..2906322 /gene="acuA" /locus_tag="BSU_29690" /old_locus_tag="BSU29690" promotor_-35 2905895..2905903 /Source="Nicolas_upshift_promotors" /id="U2305" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.931068931068931" /psig="0.931068931068931" /xcortree=1263 /SigmaFactorBS="tcccgaagggcgcattattattgccagagacgGCCGAACCAt tgtcggctatgtCACGTATTTATATCCTGACCcgctcgaaagatggtctgaaggaaat a" /listShort="acuB, acuC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2905917..2905936 /Source="Nicolas_upshift_promotors" /id="U2305" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.931068931068931" /psig="0.931068931068931" /xcortree=1263 /SigmaFactorBS="tcccgaagggcgcattattattgccagagacgGCCGAACCAt tgtcggctatgtCACGTATTTATATCCTGACCcgctcgaaagatggtctgaaggaaat a" /listShort="acuB, acuC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2905923 /Source="Nicolas_upshifts" /id="U2305" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.931068931068931" /psig="0.931068931068931" /xcortree=1263 /SigmaFactorBS="tcccgaagggcgcattattattgccagagacgGCCGAACCAt tgtcggctatgtCACGTATTTATATCCTGACCcgctcgaaagatggtctgaaggaaat a" /listShort="acuB, acuC" /GFF_Attribute="listLong" CDS 2906349..2906993 /gene="acuB" /locus_tag="BSU_29700" /old_locus_tag="BSU29700" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:7934817, 10368162, 10809684, 11274109, 16855235, 18487328" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7934817, 10368162, 10809684, 11274109, 16855235, 18487328; Product type f : factor" /codon_start=1 /transl_table=11 /product="component of the acetyl-coenzyme A synthetase regulation pathway" /protein_id="NP_390848.1" /db_xref="EnsemblGenomes-Gn:BSU29700" /db_xref="EnsemblGenomes-Tr:CAB14948" /db_xref="GOA:P39066" /db_xref="InterPro:IPR000644" /db_xref="SubtiList:BG10368" /db_xref="UniProtKB/Swiss-Prot:P39066" /translation="MIVEQIMKRDVITLTKTDTLETAICKLKEFHIRHLPVVDEERHV IGMITDRDMKQASPSIFEENKRSLFLTRSVDSIMKKDVVCAHPLDFVEEISAVFYEHG IGCLPVVHHQKLIGILTKTDLLRTFVKLTGADQPGSQIEIKVNDITKSLAEISSLCQD LQVKILSVLVYPHDDPGVKVLVFRVKTMNPLPFLQALQRNGHHVVWPSEQRDLL*" gene 2906349..2906993 /gene="acuB" /locus_tag="BSU_29700" /old_locus_tag="BSU29700" CDS 2906990..2908153 /gene="acuC" /locus_tag="BSU_29710" /old_locus_tag="BSU29710" /EC_number="3.5.1.-" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:7934817, 10368162, 10809684, 11274109, 16855235, 18487328" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7934817, 10368162, 10809684, 11274109, 16855235, 18487328; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="protein deacetylase (regulates AcsA activity)" /protein_id="NP_390849.1" /db_xref="EnsemblGenomes-Gn:BSU29710" /db_xref="EnsemblGenomes-Tr:CAB14949" /db_xref="GOA:P39067" /db_xref="InterPro:IPR000286" /db_xref="InterPro:IPR003085" /db_xref="InterPro:IPR023696" /db_xref="InterPro:IPR023801" /db_xref="InterPro:IPR037138" /db_xref="SubtiList:BG10367" /db_xref="UniProtKB/Swiss-Prot:P39067" /translation="MRDSVFIYSPSYQTYMFHQEHPFNQQRVLLTYDLLKTINAFDDG DIVTPRLASEEELSLVHTDDYIQAVKLAGAGKLPAEEGESYGLGTEDTPVFAGMHEAA SLLVGGTLTAADWVMSGQALHAANLGGGLHHGFRGRASGFCIYNDSAVAIQYIQKKYS ARVLYIDTDAHHGDGVQFTFYDNPDVCTLSIHETGRYLFPGTGQIQEKGSGKGYGYSF NIPLDAFTEDDSFLEAYRTAASEVAAYFEPDVIISQNGADAHYYDPLTHLSATINIYE EIPRLAHTLAHQYCGGKWIAVGGGGYDIWRVVPRAWARIWLEMKGIDPGHEIPPEWIV KWQKQCPVALPSSWSDPADLYPPIPRKPEITEKNAQTVSKALYAIRSEQQRTK*" gene 2906990..2908153 /gene="acuC" /locus_tag="BSU_29710" /old_locus_tag="BSU29710" downshifts 2908144 /Source="Nicolas_upshifts" /id="D1530" /incds=0 /nref=98 /ntot=231 /MaxReadThrough="0.530530000000001" /MaxDrop="6.5095" /score="10.9528437" /energy="-9.1" /TU="NA" /idTUdmin="U2304" /TUdmin="-1" /isTUend="TRUE" CDS complement(2908164..2908892) /gene="motS" /locus_tag="BSU_29720" /old_locus_tag="BSU29720" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:9260952, 15306009, 16095621, 16547058, 23049994, 28378843, 29109979" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9260952, 15306009, 16095621, 16547058, 23049994, 28378843, 29109979; Product type t: transporter" /codon_start=1 /transl_table=11 /product="sodium channel stator-force generator peptidoglycan binding subunit of flagellar rotation" /protein_id="NP_390850.1" /db_xref="EnsemblGenomes-Gn:BSU29720" /db_xref="EnsemblGenomes-Tr:CAB14950" /db_xref="GOA:P39064" /db_xref="InterPro:IPR006665" /db_xref="InterPro:IPR025713" /db_xref="InterPro:IPR036737" /db_xref="SubtiList:BG10366" /db_xref="UniProtKB/Swiss-Prot:P39064" /translation="MKLRRERFERRNGSGKNSQSSSSWMVTFTDLITLILVFFILLFS MSQIDLQKFKAAVDSIQKEGNGLQPDQTSIEKKNTSPSDTKKQEDQQDQLLKKVNTYI KDNHLKAQMTAKRDERGVVLVLQEAVLFDTGEAKVLKNAETLLHQIAVLLQTIPNDIQ VEGHTDSRNISTYRYPSNWELSAARASGVIQYFTSKEKLPSKRFIAVGYADTKPVKDN KTNEHMKENRRVEIVIKKSKTTSS*" gene complement(2908164..2908892) /gene="motS" /locus_tag="BSU_29720" /old_locus_tag="BSU29720" downshifts complement(2908200) /Source="Nicolas_upshifts" /id="D1531" /incds=0 /nref=37 /ntot=149 /MaxReadThrough="1.3853" /MaxDrop="3.98206" /score="4.77211813" /energy="-6.9" /TU="NA" /idTUdmin="U2307" /TUdmin="-1" /isTUend="TRUE" CDS complement(2908882..2909700) /gene="motP" /locus_tag="BSU_29730" /old_locus_tag="BSU29730" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:9260952, 15306009, 16095621, 16547058, 23049994, 28378843, 29109979" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9260952, 15306009, 16095621, 16547058, 23049994, 28378843, 29109979; Product type t: transporter" /codon_start=1 /transl_table=11 /product="sodium channel stator-force generator subunit offlagellar rotation" /protein_id="NP_390851.1" /db_xref="EnsemblGenomes-Gn:BSU29730" /db_xref="EnsemblGenomes-Tr:CAB14951" /db_xref="GOA:P39063" /db_xref="InterPro:IPR000540" /db_xref="InterPro:IPR002898" /db_xref="SubtiList:BG10365" /db_xref="UniProtKB/Swiss-Prot:P39063" /translation="MKRFDYLTPVGFVLGTIIIVIGIISGSGVSGFRSFLDLTSFFIV TGGLCAAVFISFPPSELKKAPSVLKQAFIRQEDNVKDLVKTFVSLSDHARKHGLLSLD DQAREIKDPFLKKGLLLAIDGWDEETIRLVMDSEIAAMEERHRKGRRVFEKAGEFAPA WGMIGTLVGLVLMLKNLNDPHMLGPNMAIALLTTLYGSLLANMVFNPIAAKLEEKTES EIFIKQVMVEGIIGVQSGKNPRNLESQLVVFSSREEWQKQPKQVKTKKGSVHEA*" gene complement(2908882..2909700) /gene="motP" /locus_tag="BSU_29730" /old_locus_tag="BSU29730" CDS complement(2909763..2910767) /gene="ccpA" /locus_tag="BSU_29740" /old_locus_tag="BSU29740" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:11931564, 14665673, 16316990, 17085448, 17827291, 18757537, 19202299, 22001508, 22512862, 23123903, 25157083, 26712933, 28617843" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11931564, 14665673, 16316990, 17085448, 17827291, 18757537, 19202299, 22001508, 22512862, 23123903, 25157083, 26712933, 28617843; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator of catabolite repression (Lacl family)" /protein_id="NP_390852.1" /db_xref="EnsemblGenomes-Gn:BSU29740" /db_xref="EnsemblGenomes-Tr:CAB14952" /db_xref="GOA:P25144" /db_xref="InterPro:IPR000843" /db_xref="InterPro:IPR006377" /db_xref="InterPro:IPR010982" /db_xref="InterPro:IPR028082" /db_xref="PDB:1ZVV" /db_xref="PDB:2FEP" /db_xref="PDB:3OQM" /db_xref="PDB:3OQN" /db_xref="PDB:3OQO" /db_xref="SubtiList:BG10376" /db_xref="UniProtKB/Swiss-Prot:P25144" /translation="MSNITIYDVAREANVSMATVSRVVNGNPNVKPTTRKKVLEAIER LGYRPNAVARGLASKKTTTVGVIIPDISSIFYSELARGIEDIATMYKYNIILSNSDQN MEKELHLLNTMLGKQVDGIVFMGGNITDEHVAEFKRSPVPIVLAASVEEQEETPSVAI DYEQAIYDAVKLLVDKGHTDIAFVSGPMAEPINRSKKLQGYKRALEEANLPFNEQFVA EGDYTYDSGLEALQHLMSLDKKPTAILSATDEMALGIIHAAQDQGLSIPEDLDIIGFD NTRLSLMVRPQLSTVVQPTYDIGAVAMRLLTKLMNKEPVEEHIVELPHRIELRKSTKS *" gene complement(2909763..2910767) /gene="ccpA" /locus_tag="BSU_29740" /old_locus_tag="BSU29740" downshifts complement(2909780) /Source="Nicolas_upshifts" /id="D1532" /incds=0 /nref=62 /ntot=239 /MaxReadThrough="4.60553" /MaxDrop="4.6531" /score="5.3377823" /energy="-13.2" /TU="U2307,U2308,U2309" /idTUdmin="U2306" /TUdmin=3 /isTUend="TRUE" misc_feature complement(2910802..2910821) /Source="Nicolas_upshift_promotors" /id="U2306" /multdbtbs="-" /comp="M5" /sig="SigA" /pcomp="0.366633366633367" /psig="0.577422577422577" /xcortree=1443 /SigmaFactorBS="cgcttacaaatcataaacgacataaattcggacattatgaca tttctctacataaaGTGTTTATGCTATAGATAAGgataagtgtatccagtaaaaggag t" /listShort="ccpA" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(2910817) /Source="Nicolas_upshifts" /id="U2306" /multdbtbs="-" /comp="M5" /sig="SigA" /pcomp="0.366633366633367" /psig="0.577422577422577" /xcortree=1443 /SigmaFactorBS="cgcttacaaatcataaacgacataaattcggacattatgaca tttctctacataaaGTGTTTATGCTATAGATAAGgataagtgtatccagtaaaaggag t" /listShort="ccpA" /GFF_Attribute="listLong" S_feature complement(2910819..2910927) /Source="Nicolas_S_feature" /locus_tag="new_3045221_3045329_c" /HighExp="Oxctl, H2O2, Paraq, MG-0.1, MG-0.2, G150, GM 15, Diami, LBGexp, G180" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA, SigA, SigB" /TUshortPSig="0.988, 1, 0.974, 1" /TUlongSig="SigH" /TUlongPSig=1 /label="S1139" promotor_-10 complement(2910927..2910946) /Source="Nicolas_upshift_promotors" /id="U2307" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.377622377622378" /psig="0.988011988011988" /xcortree=2336 /SigmaFactorBS="tagttataaaaaccaagtataCGTTTTCatcatctataaaaA CGTGTATAATTTCATGAGAagtaattaaatttgatgaataatgaaaaataatgtacac t" /listShort="S1139, ccpA, ytxD, ytxE" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2910927) /Source="Nicolas_upshifts" /id="U2307" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.377622377622378" /psig="0.988011988011988" /xcortree=2336 /SigmaFactorBS="tagttataaaaaccaagtataCGTTTTCatcatctataaaaA CGTGTATAATTTCATGAGAagtaattaaatttgatgaataatgaaaaataatgtacac t" /listShort="S1139, ccpA, ytxD, ytxE" /GFF_Attribute="listLong" S_feature complement(2910929..2910994) /Source="Nicolas_S_feature" /locus_tag="new_3045331_3045396_c" /HighExp="BMM, GM 120, Diami, GM 90, M/G, GM 25, M9-exp, HiTm, G180, Oxctl" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA, SigB" /TUshortPSig="1, 0.974, 1" /TUlongSig="SigH" /TUlongPSig=1 /label="S1140" promotor_-35 complement(2910960..2910966) /Source="Nicolas_upshift_promotors" /id="U2307" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.377622377622378" /psig="0.988011988011988" /xcortree=2336 /SigmaFactorBS="tagttataaaaaccaagtataCGTTTTCatcatctataaaaA CGTGTATAATTTCATGAGAagtaattaaatttgatgaataatgaaaaataatgtacac t" /listShort="S1139, ccpA, ytxD, ytxE" /GFF_Attribute="listLong" /label="promotor_-35" downshifts complement(2911040) /Source="Nicolas_upshifts" /id="D1533" /incds=0 /nref=66 /ntot=188 /MaxReadThrough="6.10221" /MaxDrop="6.29667" /score="46.0872381" /energy="-11.3" /TU="U2308,U2309,U2310" /idTUdmin="U2311" /TUdmin="-2" /isTUend="TRUE" CDS complement(2911043..2912119) /gene="aroX" /locus_tag="BSU_29750" /old_locus_tag="BSU29750" /EC_number="2.5.1.54" /EC_number="5.4.99.5" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:4200844, 7496534, 11444986, 16339761, 28743924" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 4200844, 7496534, 11444986, 16339761, 28743924; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="bifunctional chorismate mutase type II-isozyme 3(regulatory domain); 3-deoxy-D-arabino-heptulosonate7-phosphate synthase" /protein_id="NP_390853.1" /db_xref="EnsemblGenomes-Gn:BSU29750" /db_xref="EnsemblGenomes-Tr:CAB14953" /db_xref="GOA:P39912" /db_xref="InterPro:IPR002701" /db_xref="InterPro:IPR006218" /db_xref="InterPro:IPR006268" /db_xref="InterPro:IPR010954" /db_xref="InterPro:IPR013785" /db_xref="InterPro:IPR036979" /db_xref="PDB:5GMU" /db_xref="PDB:5GO2" /db_xref="SubtiList:BG10375" /db_xref="UniProtKB/Swiss-Prot:P39912" /translation="MSNTELELLRQKADELNLQILKLINERGNVVKEIGKAKEAQGVN RFDPVRERTMLNNIIENNDGPFENSTIQHIFKEIFKAGLELQEEDHSKALLVSRKKKP EDTIVDIKGEKIGDGQQRFIVGPCAVESYEQVAEVAAAAKKQGIKILRGGAFKPRTSP YDFQGLGVEGLQILKRVADEFDLAVISEIVTPAHIEEALDYIDVIQIGARNMQNFELL KAAGAVKKPVLLKRGLAATISEFINAAEYIMSQGNDQIILCERGIRTYETATRNTLDI SAVPILKQETHLPVFVDVTHSTGRRDLLLPTAKAALAIGADGVMAEVHPDPSVALSDS AQQMAIPEFEKWLNELKPMVKVNA*" gene complement(2911043..2912119) /gene="aroX" /locus_tag="BSU_29750" /old_locus_tag="BSU29750" promotor_-10 complement(2912160..2912179) /Source="Nicolas_upshift_promotors" /id="U2308" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.908091908091908" /psig=1 /xcortree=3058 /SigmaFactorBS="taataaagtagagtttttataaaattttttgtatttcagTAT TTCCAtttggaattacttaTAGTAAGATGCATGATAACTacaaaataaaaaatgaatg t" /listShort="aroA, S1140, S1139, ccpA, ytxD" /listLong="ytxE" /label="promotor_-10" upshifts complement(2912180) /Source="Nicolas_upshifts" /id="U2308" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.908091908091908" /psig=1 /xcortree=3058 /SigmaFactorBS="taataaagtagagtttttataaaattttttgtatttcagTAT TTCCAtttggaattacttaTAGTAAGATGCATGATAACTacaaaataaaaaatgaatg t" /listShort="aroA, S1140, S1139, ccpA, ytxD" /listLong="ytxE" S_feature complement(2912182..2912282) /Source="Nicolas_S_feature" /locus_tag="new_3046584_3046684_c" /HighExp="Lbtran, BMM, dia5, GM 25, GM 90, M9-exp, MG 150, Diami, MG-0.2, SMM" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigB, SigH" /TUshortPSig="0.974, 1, 1" /TUlongSig="SigA" /TUlongPSig=1 /label="S1141" promotor_-35 complement(2912194..2912201) /Source="Nicolas_upshift_promotors" /id="U2308" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.908091908091908" /psig=1 /xcortree=3058 /SigmaFactorBS="taataaagtagagtttttataaaattttttgtatttcagTAT TTCCAtttggaattacttaTAGTAAGATGCATGATAACTacaaaataaaaaatgaatg t" /listShort="aroA, S1140, S1139, ccpA, ytxD" /listLong="ytxE" /label="promotor_-35" downshifts 2912216 /Source="Nicolas_upshifts" /id="D1534" /incds=0 /nref=1 /ntot=9 /MaxReadThrough="2.07872" /MaxDrop="3.23284" /score="1.10447256" /energy="-7.6" /TU="NA" /idTUdmin="U2304" /TUdmin=4071 /isTUend="FALSE" promotor_-10 complement(2912270..2912289) /Source="Nicolas_upshift_promotors" /id="U2309" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.453546453546454" /psig="0.974025974025974" /xcortree=3018 /SigmaFactorBS="agatatcatctggcgcttttttttgtaaaaaacCCTTGAAca ttgccctcacaTCATGTAGGATAGCTTCATAgattactttatcacttaaaagcgtttg g" /listShort="S1141, aroA, S1140, S1139, ccpA, ytxD, ytxE" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2912282) /Source="Nicolas_upshifts" /id="U2309" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.453546453546454" /psig="0.974025974025974" /xcortree=3018 /SigmaFactorBS="agatatcatctggcgcttttttttgtaaaaaacCCTTGAAca ttgccctcacaTCATGTAGGATAGCTTCATAgattactttatcacttaaaagcgtttg g" /listShort="S1141, aroA, S1140, S1139, ccpA, ytxD, ytxE" /GFF_Attribute="listLong" promotor_-35 complement(2912303..2912309) /Source="Nicolas_upshift_promotors" /id="U2309" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.453546453546454" /psig="0.974025974025974" /xcortree=3018 /SigmaFactorBS="agatatcatctggcgcttttttttgtaaaaaacCCTTGAAca ttgccctcacaTCATGTAGGATAGCTTCATAgattactttatcacttaaaagcgtttg g" /listShort="S1141, aroA, S1140, S1139, ccpA, ytxD, ytxE" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2912355..2912681) /gene="brxJ" /locus_tag="BSU_29760" /old_locus_tag="BSU29760" /function="16.6: Maintain" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:8733232, 22938038, 25852656" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8733232, 22938038, 25852656; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="bacilliredoxin involved in debacillithiolation" /protein_id="NP_390854.1" /db_xref="EnsemblGenomes-Gn:BSU29760" /db_xref="EnsemblGenomes-Tr:CAB14954" /db_xref="InterPro:IPR022551" /db_xref="InterPro:IPR036249" /db_xref="SubtiList:BG10373" /db_xref="UniProtKB/Swiss-Prot:P39914" /translation="MAKQLIQSEEEFKRIAEQEGVFVFLKHSTTCPISQAAFHEFDAF ANQHEDVPAYYLQVQEARPLSNFIAETYGVKHESPQIFIIQNGEVKWHTSHSQITEAA IEQHLS*" gene complement(2912355..2912681) /gene="brxJ" /locus_tag="BSU_29760" /old_locus_tag="BSU29760" downshifts complement(2912364) /Source="Nicolas_upshifts" /id="D1535" /incds=0 /nref=144 /ntot=286 /MaxReadThrough="7.09736" /MaxDrop="5.96753" /score="13.8032115" /energy="-7.6" /TU="U2310,U2311" /idTUdmin="U2313" /TUdmin="-6" /isTUend="TRUE" CDS complement(2912705..2913160) /gene="ytxH" /locus_tag="BSU_29770" /old_locus_tag="BSU29770" /function="16.6: Maintain" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 8733232, 16291680" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_390855.2" /db_xref="EnsemblGenomes-Gn:BSU29770" /db_xref="EnsemblGenomes-Tr:CAB14955" /db_xref="InterPro:IPR024623" /db_xref="SubtiList:BG10975" /db_xref="UniProtKB/Swiss-Prot:P40780" /translation="MSKDGINSKDFLIGTLIGGIIGATTALFLAPKSGKELRDDLGSQ AVALRDKTDKMTADAKEKGTQYVSIAKDKTSNITQLVADQSGQIMNKVKDLRDRSKSD KTDSSTAMQDMREEAMQAADETKDQVLQTKEDVKDELKDAQKQAEQLNR*" gene complement(2912705..2913160) /gene="ytxH" /locus_tag="BSU_29770" /old_locus_tag="BSU29770" CDS complement(2913191..2913613) /gene="ytxG" /locus_tag="BSU_29780" /old_locus_tag="BSU29780" /function="16.6: Maintain" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:8733232, 22720735, 26735940" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8733232, 22720735, 26735940; Product type f: factor" /codon_start=1 /transl_table=11 /product="general stress protein" /protein_id="NP_390856.2" /db_xref="EnsemblGenomes-Gn:BSU29780" /db_xref="EnsemblGenomes-Tr:CAB14956" /db_xref="GOA:P40779" /db_xref="InterPro:IPR009293" /db_xref="SubtiList:BG10974" /db_xref="UniProtKB/Swiss-Prot:P40779" /translation="MIIILYLSVALIAVAFLVLVIYLSKTLKSLQLTLKNVASTLEGL EGQMKGITTETAELLHKTNRLAEDIQEKSEKLNTVVHAVQGVGASVQQFNTSMKQAAG SVSASVRENQDKINQVVTWSQAAMEIWEKWKQKKKSAL*" gene complement(2913191..2913613) /gene="ytxG" /locus_tag="BSU_29780" /old_locus_tag="BSU29780" promotor_-10 complement(2913634..2913652) /Source="Nicolas_upshift_promotors" /id="U2310" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=264 /SigmaFactorBS="taacggagaatagtatgtatacagcccagtacacaTGTTTAT gattgaagaaaacGGGTAAACAGCAGTATATCctgcagcaaggaggtttgagatgatt a" /listShort="ytxG, ytxH, ytxJ, S1141, aroA, S1140, S1139, ccpA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2913647) /Source="Nicolas_upshifts" /id="U2310" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=264 /SigmaFactorBS="taacggagaatagtatgtatacagcccagtacacaTGTTTAT gattgaagaaaacGGGTAAACAGCAGTATATCctgcagcaaggaggtttgagatgatt a" /listShort="ytxG, ytxH, ytxJ, S1141, aroA, S1140, S1139, ccpA" /GFF_Attribute="listLong" promotor_-35 complement(2913666..2913672) /Source="Nicolas_upshift_promotors" /id="U2310" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=264 /SigmaFactorBS="taacggagaatagtatgtatacagcccagtacacaTGTTTAT gattgaagaaaacGGGTAAACAGCAGTATATCctgcagcaaggaggtttgagatgatt a" /listShort="ytxG, ytxH, ytxJ, S1141, aroA, S1140, S1139, ccpA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(2913686..2913704) /Source="Nicolas_upshift_promotors" /id="U2311" /multdbtbs="SigH" /comp="M1" /sig="SigH" /pcomp=1 /psig=1 /xcortree=552 /SigmaFactorBS="tgctttttatttatctgatgggaaagcttattAAAGGATTTt cttacataaCGGAGAATAGTATGTATACagcccagtacacatgtttatgattgaagaa a" /listShort="ytxG, ytxH, ytxJ, S1141, aroA" /listLong="S1140, S1139, ccpA" /label="promotor_-10" upshifts complement(2913695) /Source="Nicolas_upshifts" /id="U2311" /multdbtbs="SigH" /comp="M1" /sig="SigH" /pcomp=1 /psig=1 /xcortree=552 /SigmaFactorBS="tgctttttatttatctgatgggaaagcttattAAAGGATTTt cttacataaCGGAGAATAGTATGTATACagcccagtacacatgtttatgattgaagaa a" /listShort="ytxG, ytxH, ytxJ, S1141, aroA" /listLong="S1140, S1139, ccpA" promotor_-35 complement(2913715..2913723) /Source="Nicolas_upshift_promotors" /id="U2311" /multdbtbs="SigH" /comp="M1" /sig="SigH" /pcomp=1 /psig=1 /xcortree=552 /SigmaFactorBS="tgctttttatttatctgatgggaaagcttattAAAGGATTTt cttacataaCGGAGAATAGTATGTATACagcccagtacacatgtttatgattgaagaa a" /listShort="ytxG, ytxH, ytxJ, S1141, aroA" /listLong="S1140, S1139, ccpA" /label="promotor_-35" CDS complement(2913775..2915073) /gene="murC" /locus_tag="BSU_29790" /old_locus_tag="BSU29790" /EC_number="6.3.2.8" /function="16.13: Shape" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 10565540, 12682299, 12781748; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="UDP-N-acetyl muramate-alanine ligase" /protein_id="NP_390857.1" /db_xref="EnsemblGenomes-Gn:BSU29790" /db_xref="EnsemblGenomes-Tr:CAB14957" /db_xref="GOA:P40778" /db_xref="InterPro:IPR000713" /db_xref="InterPro:IPR004101" /db_xref="InterPro:IPR005758" /db_xref="InterPro:IPR013221" /db_xref="InterPro:IPR036565" /db_xref="InterPro:IPR036615" /db_xref="SubtiList:BG10973" /db_xref="UniProtKB/Swiss-Prot:P40778" /translation="MTVYHFVGIKGTGMSPLAQILHDNGYTVQGSDIEKFIFTQTALE KRNITILPFSAENIKPGMTVIAGNAFPDTHPEIEKAMSEGIPVIRYHKFLGDYMKKFT SVAVTGAHGKTSTTGLLAHVIQNAKPTSFLIGDGTGQGNENSEYFVFEACEYRRHFLS YQPDYAIMTNIDFDHPDYFSSIDDVFDAFQEMALQVNKGIIACGDDEHLPKIHANVPV VYYGTGEENDFQARNIVKSTEGTTFDVFVRNTFYDTFYIPAYGHHNVLNSLAVIALCH YEEIDSSIIKHALKSFGGVKRRFNEKQLGDQVLIDDYAHHPTEIKVTIEAARQKYPDR EIVAVFQPHTFTRTQQFLDEFAESLSGADCVYLCDIFGSARENAGKLTIGDLQGKIHN AKLIEEDDTSVLKAHDKAVLIFMGAGDIQKYMRAYENVMA*" gene complement(2913775..2915073) /gene="murC" /locus_tag="BSU_29790" /old_locus_tag="BSU29790" downshifts complement(2913784) /Source="Nicolas_upshifts" /id="D1536" /incds=0 /nref=29 /ntot=180 /MaxReadThrough="5.23049" /MaxDrop="5.42617" /score="15.3729968" /energy="-7.5" /TU="U2313,U2314" /idTUdmin="U2312" /TUdmin="-5" /isTUend="TRUE" promotor_-10 complement(2915098..2915117) /Source="Nicolas_upshift_promotors" /id="U2312" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.994005994005994" /psig="0.994005994005994" /xcortree=1225 /SigmaFactorBS="agggaggcttttcagccgccGCGGTCGCAAattgaaatgagc GTCATATACTGGGGAACAGAtagacgtttgttggaggtacaattatgactgtttatca t" /listShort="murC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2915099) /Source="Nicolas_upshifts" /id="U2312" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.994005994005994" /psig="0.994005994005994" /xcortree=1225 /SigmaFactorBS="agggaggcttttcagccgccGCGGTCGCAAattgaaatgagc GTCATATACTGGGGAACAGAtagacgtttgttggaggtacaattatgactgtttatca t" /listShort="murC" /GFF_Attribute="listLong" S_feature complement(2915101..2915297) /Source="Nicolas_S_feature" /locus_tag="new_3049503_3049699_c" /HighExp="Cold, G150, G135, dia15, G180, H2O2, C30, Oxctl, Paraq, LBGexp" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="1, 1" /TUlongSig="SigA" /TUlongPSig="0.938" /label="S1142" promotor_-35 complement(2915130..2915139) /Source="Nicolas_upshift_promotors" /id="U2312" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.994005994005994" /psig="0.994005994005994" /xcortree=1225 /SigmaFactorBS="agggaggcttttcagccgccGCGGTCGCAAattgaaatgagc GTCATATACTGGGGAACAGAtagacgtttgttggaggtacaattatgactgtttatca t" /listShort="murC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(2915280..2915299) /Source="Nicolas_upshift_promotors" /id="U2313" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.755244755244755" /psig=1 /xcortree=2585 /SigmaFactorBS="tgctgatcacagcaagtgatttaataaacgaataatatggGT TCATTttcacaccaaaCATGGTATGATAGTGTTTAGagcatttaacagctatgccgct t" /listShort="S1142, murC, ytxG, ytxH, ytxJ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2915297) /Source="Nicolas_upshifts" /id="U2313" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.755244755244755" /psig=1 /xcortree=2585 /SigmaFactorBS="tgctgatcacagcaagtgatttaataaacgaataatatggGT TCATTttcacaccaaaCATGGTATGATAGTGTTTAGagcatttaacagctatgccgct t" /listShort="S1142, murC, ytxG, ytxH, ytxJ" /GFF_Attribute="listLong" promotor_-35 complement(2915311..2915317) /Source="Nicolas_upshift_promotors" /id="U2313" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.755244755244755" /psig=1 /xcortree=2585 /SigmaFactorBS="tgctgatcacagcaagtgatttaataaacgaataatatggGT TCATTttcacaccaaaCATGGTATGATAGTGTTTAGagcatttaacagctatgccgct t" /listShort="S1142, murC, ytxG, ytxH, ytxJ" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2915323..2918181) /gene="sftA" /locus_tag="BSU_29805" /old_locus_tag="BSU29805" /function="8.1: DNA replication, recombination, and repair" /experiment="publication(s) with functional evidences, PMID:3129532, 11134515, 11208805, 19788545, 28110333" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 3129532, 11134515, 11208805, 19788545, 28110333; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="DNA translocase" /protein_id="NP_390859.2" /db_xref="EnsemblGenomes-Gn:BSU29805" /db_xref="EnsemblGenomes-Tr:CAB14959" /db_xref="GOA:C0SP86" /db_xref="InterPro:IPR002543" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR018541" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG13906" /db_xref="UniProtKB/Swiss-Prot:C0SP86" /translation="MSWLHKFFDLFLGESEEDAERETKPAQIPQQQEVHHPEGQLKRL EDPKIYYEYPKGKFRFPVVPDGYKNHDLRRRRTPSDEPKSAPRPSAAPYRERPRNEEE QHTYQAAEPAKKPFKPTNIPSPVYGFNQKPSVKKDVPKKPSETLNEPDKSVKEKVTLL SEEIERERGYPASDTQAHSKIESPFFPDTQFEKQPSGVLNRKDTEHDEALAKRPAEPS GNKVPFESGVQQPEKEEPFFPAEQAEEQTPPEMLTDTAAEGLSDSEVGREEPATAEEE QREQQPEKFEEPVFSAELDEEQTAPESQTEAVSEDEKAKEPSDSPVYNHHENAAEGAE SPFVQEEQMDIRQEEPLFTDHEYSSEALAQAETVAKESEEPSESIINNHYDTLGEAQE TKIDVQPDSHTELEKTEHMEQGSKSSTATLENRQEIRADKPREASEEPKKRPGVQEKR TEQSASSQKGPSVPFNVMMLKRDTHKQQKAEERRGSYVFPNVALLDVPPAQVQDDTAW IEEQRQLLDLTLKNFNVRANVVHVTQGPSVTRFEVHPEPGVKVNKITNLSDDIKLSLS AKDIRIEAPIPGKNTIGIEVPNRTSKVVDLRQMIRSSAFRTSKSPLTAALGLDISGNP VVIDLKKMPHGLIAGATGSGKSVCINTILVSLLYKADPSEVKVLLIDPKMVELAPYNK IPHLVSPVITDAKAATAALKWVVEEMERRYELFAHSGVRDIDRFNQLTAEHQMGEKLP YLVVIIDELADLMMVAPNDVEESIARIAQKARACGIHLLVATQRPSVDVITGLIKANI PTRIAFSVSSQVDSRTIIDIAGAEKLLGKGDMLFLENGSGKPVRLQGNFVSDREIDRV VSHVRSQMPPTYLFEQEELVRQGSALKEEDELFYEACEFVVEQNSASTSSLQRRFRIG YNRAARLIDMMEAEGMISEAKGSKPREVLITASDLINE*" gene complement(2915323..2918181) /gene="sftA" /locus_tag="BSU_29805" /old_locus_tag="BSU29805" promotor_-10 complement(2918215..2918234) /Source="Nicolas_upshift_promotors" /id="U2314" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.983016983016983" /psig=1 /xcortree=2568 /SigmaFactorBS="tttagcggctttgtttctgctgatagcttaaTCTTTtctggg ccgaccagcAGTGGTATACTAAAAACCGTcccagaaaactataagggagttagagata a" /listShort="ytpS, S1142, murC, ytxG, ytxH, ytxJ" /listLong="S1141, aroA" /label="promotor_-10" upshifts complement(2918225) /Source="Nicolas_upshifts" /id="U2314" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.983016983016983" /psig=1 /xcortree=2568 /SigmaFactorBS="tttagcggctttgtttctgctgatagcttaaTCTTTtctggg ccgaccagcAGTGGTATACTAAAAACCGTcccagaaaactataagggagttagagata a" /listShort="ytpS, S1142, murC, ytxG, ytxH, ytxJ" /listLong="S1141, aroA" promotor_-35 complement(2918250..2918254) /Source="Nicolas_upshift_promotors" /id="U2314" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.983016983016983" /psig=1 /xcortree=2568 /SigmaFactorBS="tttagcggctttgtttctgctgatagcttaaTCTTTtctggg ccgaccagcAGTGGTATACTAAAAACCGTcccagaaaactataagggagttagagata a" /listShort="ytpS, S1142, murC, ytxG, ytxH, ytxJ" /listLong="S1141, aroA" /label="promotor_-35" downshifts complement(2918324) /Source="Nicolas_upshifts" /id="D1537" /incds=0 /nref=186 /ntot=249 /MaxReadThrough="4.47299" /MaxDrop="6.35097" /score="9.62039509" /energy="-14.5" /TU="U2315" /idTUdmin="U2315" /TUdmin="-1553" /isTUend="FALSE" CDS complement(2918341..2918946) /gene="ytpR" /locus_tag="BSU_29820" /old_locus_tag="BSU29820" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 21949854, 27435445; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative tRNA binding enzyme" /protein_id="NP_390860.1" /db_xref="EnsemblGenomes-Gn:BSU29820" /db_xref="EnsemblGenomes-Tr:CAB14960" /db_xref="GOA:O34943" /db_xref="InterPro:IPR002547" /db_xref="InterPro:IPR012340" /db_xref="InterPro:IPR027855" /db_xref="InterPro:IPR033714" /db_xref="InterPro:IPR037154" /db_xref="SubtiList:BG13905" /db_xref="UniProtKB/Swiss-Prot:O34943" /translation="MNAFYNKEGVGDTLLISLQDVTREQLGYEKHGDVVKIFNNETKE TTGFNIFNASSYLTIDENGPVALSETFVQDVNEILNRNGVEETLVVDLSPKFVVGYVE SKEKHPNADKLSVCKVNVGEETLQIVCGAPNVDQGQKVVVAKVGAVMPSGLVIKDAEL RGVPSSGMICSAKELDLPDAPAEKGILVLEGDYEAGDAFQF*" gene complement(2918341..2918946) /gene="ytpR" /locus_tag="BSU_29820" /old_locus_tag="BSU29820" CDS complement(2918962..2919771) /gene="ytpQ" /locus_tag="BSU_29830" /old_locus_tag="BSU29830" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 12719520, 21949854" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function (iron homeostasis)" /protein_id="NP_390861.1" /db_xref="EnsemblGenomes-Gn:BSU29830" /db_xref="EnsemblGenomes-Tr:CAB14961" /db_xref="InterPro:IPR010838" /db_xref="SubtiList:BG13904" /db_xref="UniProtKB/Swiss-Prot:O34496" /translation="MKMTSRKLSDILKQRLQHENRSFLFDREKDTLRVEDQTTKKGIT LDLPPIIAKWELKKDEAIDEIVYYVSEAMTAMEGKAQEMTGKETRIYPVIRSTSFPDK SSEDIPLIYDDHTAETRIYYALDLGKTYRLIDQRMLEKENWTKERIRETAAFNLRSLP TVVKEDTVAGNYFYFFRANDGYDASRILNEAILNEYKQHAEGELAISVPHQDVLILAD IRNESGYDILGQMSMSFFAGGTVPITALSFLYNEGKLEPVFILAKSRPKKD*" gene complement(2918962..2919771) /gene="ytpQ" /locus_tag="BSU_29830" /old_locus_tag="BSU29830" CDS complement(2919786..2920109) /gene="ytpP" /locus_tag="BSU_29840" /old_locus_tag="BSU29840" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 12719520, 15937154, 21949854; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative thiol-disulfide oxidoreductase with thioredoxin domain" /protein_id="NP_390862.1" /db_xref="EnsemblGenomes-Gn:BSU29840" /db_xref="EnsemblGenomes-Tr:CAB14962" /db_xref="GOA:O34357" /db_xref="InterPro:IPR005746" /db_xref="InterPro:IPR013766" /db_xref="InterPro:IPR036249" /db_xref="SubtiList:BG13903" /db_xref="UniProtKB/Swiss-Prot:O34357" /translation="MKKIESTQELEKAVKDDWSVFMFSADWCPDCRFVEPFLPELEAN FPEFTYYYVDRDKFIDTCAEWEIYGIPSFVVFNEGKEVNRFVSKDRKTKEEIEQFLTD SLAKA*" gene complement(2919786..2920109) /gene="ytpP" /locus_tag="BSU_29840" /old_locus_tag="BSU29840" S_feature complement(2920110..2920248) /Source="Nicolas_S_feature" /locus_tag="new_3054512_3054650_c" /HighExp="G180, G150, Paraq, Oxctl, H2O2, Diami, C90, dia15, G135, LBGexp" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.32150299999999998" /TUshortSig="SigA" /TUshortPSig="0.938" /TUlongSig="NA" /TUlongPSig="NA" /label="S1143" CDS complement(2920148..2920264) /locus_tag="BSU_29845" /old_locus_tag="BSU29845" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_009513998.1" /translation="MQIKYDNDNGKANLTYSFVAYKWFCLKQFGMIQMDEYR*" gene complement(2920148..2920264) /locus_tag="BSU_29845" /old_locus_tag="BSU29845" promotor_-10 complement(2920235..2920254) /Source="Nicolas_upshift_promotors" /id="U2315" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.515484515484515" /psig="0.938061938061938" /xcortree=2564 /SigmaFactorBS="atttcaccctcatgtacacgatgttaaacgaaacgagcTtga taatgcaaataaAATATGATAATGATAATGGGaaagccaatcttacatattcattcgt t" /listShort="S1143, ytpP, ytpQ, ytpR, ytpS" /listLong="S1142, murC, ytxG, ytxH, ytxJ" /label="promotor_-10" upshifts complement(2920248) /Source="Nicolas_upshifts" /id="U2315" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.515484515484515" /psig="0.938061938061938" /xcortree=2564 /SigmaFactorBS="atttcaccctcatgtacacgatgttaaacgaaacgagcTtga taatgcaaataaAATATGATAATGATAATGGGaaagccaatcttacatattcattcgt t" /listShort="S1143, ytpP, ytpQ, ytpR, ytpS" /listLong="S1142, murC, ytxG, ytxH, ytxJ" promotor_-35 2920256..2920263 /Source="Nicolas_upshift_promotors" /id="U2316" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.925074925074925" /psig="0.98101898101898" /xcortree=2351 /SigmaFactorBS="aagattggctttcccattatcattatcatatttTATTTGCAt tatcaagctcgttTCGTTTAACATCGTGTACATgagggtgaaatttacagatggatat a" /listShort="ytoQ, S1144" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 complement(2920270) /Source="Nicolas_upshift_promotors" /id="U2315" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.515484515484515" /psig="0.938061938061938" /xcortree=2564 /SigmaFactorBS="atttcaccctcatgtacacgatgttaaacgaaacgagcTtga taatgcaaataaAATATGATAATGATAATGGGaaagccaatcttacatattcattcgt t" /listShort="S1143, ytpP, ytpQ, ytpR, ytpS" /listLong="S1142, murC, ytxG, ytxH, ytxJ" /label="promotor_-35" promotor_-10 2920278..2920297 /Source="Nicolas_upshift_promotors" /id="U2316" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.925074925074925" /psig="0.98101898101898" /xcortree=2351 /SigmaFactorBS="aagattggctttcccattatcattatcatatttTATTTGCAt tatcaagctcgttTCGTTTAACATCGTGTACATgagggtgaaatttacagatggatat a" /listShort="ytoQ, S1144" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2920283 /Source="Nicolas_upshifts" /id="U2316" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.925074925074925" /psig="0.98101898101898" /xcortree=2351 /SigmaFactorBS="aagattggctttcccattatcattatcatatttTATTTGCAt tatcaagctcgttTCGTTTAACATCGTGTACATgagggtgaaatttacagatggatat a" /listShort="ytoQ, S1144" /GFF_Attribute="listLong" CDS 2920344..2920790 /gene="ytoQ" /locus_tag="BSU_29850" /old_locus_tag="BSU29850" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative enzyme with sugar binding fold" /protein_id="NP_390863.1" /db_xref="EnsemblGenomes-Gn:BSU29850" /db_xref="EnsemblGenomes-Tr:CAB14963" /db_xref="InterPro:IPR019884" /db_xref="SubtiList:BG13899" /db_xref="UniProtKB/Swiss-Prot:O34305" /translation="MEFIVYLAGEIHSNWREEIKEKTKSLKLPITFVGPMENHDRSDN IGEEIMGVQPNAVLKDDKASDINNFRTAVLMNKADFVIALFGEKYKQWNTAMDASYAI AKGKPLIIIRPESLHHPLKELSNKANITVETVNQAIKALSYLFETE*" gene 2920344..2920790 /gene="ytoQ" /locus_tag="BSU_29850" /old_locus_tag="BSU29850" S_feature 2920791..2921519 /Source="Nicolas_S_feature" /locus_tag="new_3055193_3055921" /HighExp="H2O2, dia15, C30, C90, Diami, S1, M0t45, Salt, Paraq, Lbexp" /AntisenseName="ytoP" /AntisenseCor="0.35418735783791" /AntisenseRegPval="-8.6" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.981" /TUlongSig="NA" /TUlongPSig="NA" /label="S1144" CDS complement(2920845..2921918) /gene="ytoP" /locus_tag="BSU_29860" /old_locus_tag="BSU29860" /EC_number="3.4.-.-" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 8535515; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative modified amino acid aminopeptidase" /protein_id="NP_390864.1" /db_xref="EnsemblGenomes-Gn:BSU29860" /db_xref="EnsemblGenomes-Tr:CAB14964" /db_xref="GOA:O34924" /db_xref="InterPro:IPR008007" /db_xref="InterPro:IPR023367" /db_xref="SubtiList:BG13898" /db_xref="UniProtKB/Swiss-Prot:O34924" /translation="MNQETKALFQTLTQLPGAPGNEHQVRAFMKQELAKYADDIVQDR LGSVFGVRRGAEDAPRIMVAGHMDEVGFMVTSITDNGLLRFQTLGGWWSQVLLAQRVE IQTDNGPVPGVISSIPPHLLTDAQRNRPMDIKNMMIDIGADDKEDAIKIGIRPGQQIV PVCPFTTMANEKKILSKAWDNRYGCGLSIELLKELHGKELPNTLYAGATVQEEVGLRG AQTASHMIKPDLFFALDASPANDMSGDKNEFGQLGKGFLLRILDRTTVMHRGMREFVL DMAETHDIPYQYFVSGGGTDAGKVHISNSGVPSAVIGICSRYIHTNATIIHIDDYAAA KEMLIKLVTACDKQTVDAIKENM*" gene complement(2920845..2921918) /gene="ytoP" /locus_tag="BSU_29860" /old_locus_tag="BSU29860" downshifts complement(2920864) /Source="Nicolas_upshifts" /id="D1538" /incds=0 /nref=140 /ntot=248 /MaxReadThrough="1.89952" /MaxDrop="4.55096" /score="14.9571314" /energy="-14.4" /TU="NA" /idTUdmin="U2317" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(2921940..2921959) /Source="Nicolas_upshift_promotors" /id="U2317" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.701298701298701" /psig="0.998001998001998" /xcortree=2339 /SigmaFactorBS="ctgatcgagcagattgggtcagagTGCTTGGAaaacttcatt gttTCTAATAAAATAAAAGGACTacatagaaatgaggggaaaacatgaatcaagaaac g" /listShort="ytoP" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2921944) /Source="Nicolas_upshifts" /id="U2317" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.701298701298701" /psig="0.998001998001998" /xcortree=2339 /SigmaFactorBS="ctgatcgagcagattgggtcagagTGCTTGGAaaacttcatt gttTCTAATAAAATAAAAGGACTacatagaaatgaggggaaaacatgaatcaagaaac g" /listShort="ytoP" /GFF_Attribute="listLong" promotor_-35 complement(2921973..2921980) /Source="Nicolas_upshift_promotors" /id="U2317" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.701298701298701" /psig="0.998001998001998" /xcortree=2339 /SigmaFactorBS="ctgatcgagcagattgggtcagagTGCTTGGAaaacttcatt gttTCTAATAAAATAAAAGGACTacatagaaatgaggggaaaacatgaatcaagaaac g" /listShort="ytoP" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 2922015..2922018 /Source="Nicolas_upshift_promotors" /id="U2318" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.922077922077922" /psig=1 /xcortree=3184 /SigmaFactorBS="gcactctgacccaatctgctcgatcagccgcgtattgCTTAa caggatttggctgTTTCTGTATAATGAAAAGTAcgatcaaccaggaggtgctttattt t" /listShort="ytzB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2922033..2922052 /Source="Nicolas_upshift_promotors" /id="U2318" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.922077922077922" /psig=1 /xcortree=3184 /SigmaFactorBS="gcactctgacccaatctgctcgatcagccgcgtattgCTTAa caggatttggctgTTTCTGTATAATGAAAAGTAcgatcaaccaggaggtgctttattt t" /listShort="ytzB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2922038 /Source="Nicolas_upshifts" /id="U2318" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.922077922077922" /psig=1 /xcortree=3184 /SigmaFactorBS="gcactctgacccaatctgctcgatcagccgcgtattgCTTAa caggatttggctgTTTCTGTATAATGAAAAGTAcgatcaaccaggaggtgctttattt t" /listShort="ytzB" /GFF_Attribute="listLong" CDS 2922077..2922394 /gene="ytzB" /locus_tag="BSU_29870" /old_locus_tag="BSU29870" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_390865.1" /db_xref="EnsemblGenomes-Gn:BSU29870" /db_xref="EnsemblGenomes-Tr:CAB14965" /db_xref="InterPro:IPR025711" /db_xref="SubtiList:BG13936" /db_xref="UniProtKB/Swiss-Prot:O32065" /translation="MKLRHLLLGAGLGICTAVVVRQYVMKPYISSEKALRIVKSAFKQ RGPIDGSWIYTQPEPYNINGETVQVYKTGITRSAFGELEQYEVMVDAKTGEIVDVIDT IAS*" gene 2922077..2922394 /gene="ytzB" /locus_tag="BSU_29870" /old_locus_tag="BSU29870" downshifts 2922394 /Source="Nicolas_upshifts" /id="D1539" /incds=0 /nref=250 /ntot=259 /MaxReadThrough="1.29231" /MaxDrop="7.83082" /score="44.9062865" /energy="-17" /TU="NA" /idTUdmin="U2318" /TUdmin=0 /isTUend="TRUE" CDS complement(2922447..2924147) /gene="maeC" /locus_tag="BSU_29880" /old_locus_tag="BSU29880" /EC_number="1.1.1.38" /function="16.11: Scavenge (Catabolism)" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:16788182, 20933603, 22740702, 23136871, 24325460" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16788182, 20933603, 22740702, 23136871, 24325460; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="NAD-dependent malic enzyme (conversion of malateinto pyruvate)" /protein_id="NP_390866.1" /db_xref="EnsemblGenomes-Gn:BSU29880" /db_xref="EnsemblGenomes-Tr:CAB14966" /db_xref="GOA:O34389" /db_xref="InterPro:IPR001891" /db_xref="InterPro:IPR012301" /db_xref="InterPro:IPR012302" /db_xref="InterPro:IPR015884" /db_xref="InterPro:IPR036291" /db_xref="InterPro:IPR037062" /db_xref="SubtiList:BG12614" /db_xref="UniProtKB/Swiss-Prot:O34389" /translation="MKQFRVTNEGDIQTTLRGLEVLSVPFLNKGVAFTEEERKELGLK GFLPPKVLTIDDQAKRAYEQYSAQPDDLSKNVYLTALHDRNETLFYRLLNDHLGEMLP IVYTPTVGTAIQRYSHEYRKPRGLYLSIDDPDGMKEAFKQYKDQSDTIDLIVATDAEG ILGIGDWGVGGIAISIGKLAVYTAAAGIDPSRVLAVVLDAGTNQESLLNDPLYVGNQH SRVRGERYDQFIDDYVALARETFPNALLHWEDFGAKNARSILKRYKDKVCTFNDDIQG TGAVSLAAVLSCAKASKVPLRDHRVVIFGAGTAGIGIAEQLREALVREGLSEEESYKR FWCIDRNGLLTDDMDQLLDFQKPYARSADEVKDYQRNGDGGGIDLLEVVRQAKPTILI GTSTVSGAFTEEIVKEMASHVKRPAILPMSNPTTLSEAKPEDLIEWTEGRALITTGSP FPPVEYNGVTYHIGQANNALVFPGLGLGTIVTKSKLITDGMFEACARAIAGMVNVGVP GAPMLPKVEDLRTVSATVAVEVAKTAMKEGVATEEPEDIIQAVQDAMWYPVYKPIRAI *" gene complement(2922447..2924147) /gene="maeC" /locus_tag="BSU_29880" /old_locus_tag="BSU29880" downshifts complement(2922466) /Source="Nicolas_upshifts" /id="D1540" /incds=0 /nref=77 /ntot=255 /MaxReadThrough="2.4872" /MaxDrop="4.99085" /score="17.675308" /energy="-15.3" /TU="NA" /idTUdmin="U2319" /TUdmin="-18" /isTUend="TRUE" promotor_-10 complement(2924179..2924197) /Source="Nicolas_upshift_promotors" /id="U2319" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.967032967032967" /psig="0.967032967032967" /xcortree=724 /SigmaFactorBS="aagcgaatgaagcgatagcatatttttaTGTTTACcctgcat gttttccGGCTAATAATGCAAACCTAgtactattatgctcagaaaggaagaggcaggg t" /listShort="malS" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2924186) /Source="Nicolas_upshifts" /id="U2319" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.967032967032967" /psig="0.967032967032967" /xcortree=724 /SigmaFactorBS="aagcgaatgaagcgatagcatatttttaTGTTTACcctgcat gttttccGGCTAATAATGCAAACCTAgtactattatgctcagaaaggaagaggcaggg t" /listShort="malS" /GFF_Attribute="listLong" promotor_-35 complement(2924212..2924218) /Source="Nicolas_upshift_promotors" /id="U2319" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.967032967032967" /psig="0.967032967032967" /xcortree=724 /SigmaFactorBS="aagcgaatgaagcgatagcatatttttaTGTTTACcctgcat gttttccGGCTAATAATGCAAACCTAgtactattatgctcagaaaggaagaggcaggg t" /listShort="malS" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2924229..2924999) /gene="ytnP" /locus_tag="BSU_29890" /old_locus_tag="BSU29890" /EC_number="3.1.1.-" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 22101040, 24268182; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative quorum-quenching lactonase" /protein_id="NP_390867.1" /db_xref="EnsemblGenomes-Gn:BSU29890" /db_xref="EnsemblGenomes-Tr:CAB14967" /db_xref="GOA:O34760" /db_xref="InterPro:IPR001279" /db_xref="InterPro:IPR036866" /db_xref="SubtiList:BG13895" /db_xref="UniProtKB/Swiss-Prot:O34760" /translation="MFGVVPKPLWSKKYPVNEKNQIELRTDPILIQKDGLNIIIDAGI GYGKLTDKQKRNYGVTQESNVKPSLAALGLTVADIDVIAMTHLHFDHACGLTEYEGER LVSVFPNAVIYTSAVEWDEMRHPNIRSKNTYWKENWEAVAGQVKTFEDTLTITEGITM HHTGGHSDGHSVLICEDAGETAVHMADLMPTHAHRNPLWVLAYDDYPMTSIPQKQKWQ AFAAEKDAWFIFYHDAEYRALQWEEDGSIKKSVKRMKR*" gene complement(2924229..2924999) /gene="ytnP" /locus_tag="BSU_29890" /old_locus_tag="BSU29890" S_feature complement(2925000..2925088) /Source="Nicolas_S_feature" /locus_tag="new_3059402_3059490_c" /HighExp="HiOs, M40t90, T0.30H, T1.30H, T3.0H, T1.0H, Sw, T2.30H, T3.30H, Gly" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.997" /TUlongSig="NA" /TUlongPSig="NA" /label="S1145" promotor_-10 complement(2925086..2925105) /Source="Nicolas_upshift_promotors" /id="U2320" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.497502497502497" /psig="0.997002997002997" /xcortree=3207 /SigmaFactorBS="gtaaagacagactctgacaggagTCTGTtttttttatgggcc gTTTGCTACCATGATGATAGGggggggtgaaaatggaaacaatgaaaattggaaacat c" /listShort="S1145, ytnP, malS" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2925088) /Source="Nicolas_upshifts" /id="U2320" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.497502497502497" /psig="0.997002997002997" /xcortree=3207 /SigmaFactorBS="gtaaagacagactctgacaggagTCTGTtttttttatgggcc gTTTGCTACCATGATGATAGGggggggtgaaaatggaaacaatgaaaattggaaacat c" /listShort="S1145, ytnP, malS" /GFF_Attribute="listLong" promotor_-35 complement(2925121..2925125) /Source="Nicolas_upshift_promotors" /id="U2320" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.497502497502497" /psig="0.997002997002997" /xcortree=3207 /SigmaFactorBS="gtaaagacagactctgacaggagTCTGTtttttttatgggcc gTTTGCTACCATGATGATAGGggggggtgaaaatggaaacaatgaaaattggaaacat c" /listShort="S1145, ytnP, malS" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2925145..2925786) /gene="trmB" /locus_tag="BSU_29900" /old_locus_tag="BSU29900" /EC_number="2.1.1.33" /function="16.6: Maintain" /function="16.3: Control" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:15789416, 16600901, 17150909, 19934251" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15789416, 16600901, 17150909, 19934251; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="tRNA (guanine-N(7)-)-methyltransferase" /protein_id="NP_390868.1" /db_xref="EnsemblGenomes-Gn:BSU29900" /db_xref="EnsemblGenomes-Tr:CAB14968" /db_xref="GOA:O34522" /db_xref="InterPro:IPR003358" /db_xref="InterPro:IPR029063" /db_xref="PDB:2FCA" /db_xref="SubtiList:BG13890" /db_xref="UniProtKB/Swiss-Prot:O34522" /translation="MRMRHKPWADDFLAENADIAISNPADYKGKWNTVFGNDNPIHIE VGTGKGQFISGMAKQNPDINYIGIELFKSVIVTAVQKVKDSEAQNVKLLNIDADTLTD VFEPGEVKRVYLNFSDPWPKKRHEKRRLTYSHFLKKYEEVMGKGGSIHFKTDNRGLFE YSLKSFSEYGLLLTYVSLDLHNSNLEGNIMTEYEEKFSALGQPIYRAEVEWRT*" gene complement(2925145..2925786) /gene="trmB" /locus_tag="BSU_29900" /old_locus_tag="BSU29900" downshifts complement(2925155) /Source="Nicolas_upshifts" /id="D1541" /incds=0 /nref=46 /ntot=131 /MaxReadThrough="3.31031" /MaxDrop="5.64644" /score="29.2137061" /energy="-10.1" /TU="NA" /idTUdmin="U2321" /TUdmin="-1" /isTUend="TRUE" downshifts complement(2925220) /Source="Nicolas_upshifts" /id="D1542" /incds=1 /nref=39 /ntot=202 /MaxReadThrough="6.31908" /MaxDrop="3.64275" /score="29.2137061" /energy="-10.1" /TU="U2321,U2323" /idTUdmin="U2323" /TUdmin="-44" /isTUend="FALSE" promotor_-10 complement(2925812..2925831) /Source="Nicolas_upshift_promotors" /id="U2321" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.916083916083916" /psig="0.999000999001" /xcortree=2613 /SigmaFactorBS="ggccttaagagagatacactggaaaaacgaGCTTGcgggtct ttttaattCATGGTATGTTGTTAGTCGAaataatagatagaggtgtcaatcatatgag a" /listShort="trmB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2925821) /Source="Nicolas_upshifts" /id="U2321" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.916083916083916" /psig="0.999000999001" /xcortree=2613 /SigmaFactorBS="ggccttaagagagatacactggaaaaacgaGCTTGcgggtct ttttaattCATGGTATGTTGTTAGTCGAaataatagatagaggtgtcaatcatatgag a" /listShort="trmB" /GFF_Attribute="listLong" S_feature complement(2925823..2926271) /Source="Nicolas_S_feature" /locus_tag="new_3060225_3060673_c" /HighExp="C30, Cold, G135, G180, B60, Paraq, G150, Oxctl, H2O2, LBGstat" /AntisenseName="ytzH" /AntisenseCor="-0.51149457663808795" /AntisenseRegPval="-18.600000000000001" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.999" /TUlongSig="SigD, SigA" /TUlongPSig="1, 0.992" /label="S1146" promotor_-35 complement(2925847..2925851) /Source="Nicolas_upshift_promotors" /id="U2321" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.916083916083916" /psig="0.999000999001" /xcortree=2613 /SigmaFactorBS="ggccttaagagagatacactggaaaaacgaGCTTGcgggtct ttttaattCATGGTATGTTGTTAGTCGAaataatagatagaggtgtcaatcatatgag a" /listShort="trmB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 2925930..2925936 /Source="Nicolas_upshift_promotors" /id="U2322" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=942 /SigmaFactorBS="agggtcccgtctgctggaacactcctttcccaTGTATAAaaa cgctctgttttGAACAATTTAACccgtatgatactgaagggatgtgtaccgttatggg t" /listShort="ytzH, S1147" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2925951..2925962 /Source="Nicolas_upshift_promotors" /id="U2322" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=942 /SigmaFactorBS="agggtcccgtctgctggaacactcctttcccaTGTATAAaaa cgctctgttttGAACAATTTAACccgtatgatactgaagggatgtgtaccgttatggg t" /listShort="ytzH, S1147" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2925958 /Source="Nicolas_upshifts" /id="U2322" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=942 /SigmaFactorBS="agggtcccgtctgctggaacactcctttcccaTGTATAAaaa cgctctgttttGAACAATTTAACccgtatgatactgaagggatgtgtaccgttatggg t" /listShort="ytzH, S1147" /GFF_Attribute="listLong" CDS 2925993..2926271 /gene="ytzH" /locus_tag="BSU_29910" /old_locus_tag="BSU29910" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_390869.1" /db_xref="EnsemblGenomes-Gn:BSU29910" /db_xref="EnsemblGenomes-Tr:CAB14969" /db_xref="InterPro:IPR025547" /db_xref="SubtiList:BG13942" /db_xref="UniProtKB/Swiss-Prot:O32066" /translation="MGLHYEHQVHLLKDILTDHQLDCCGTVAEYEQLERVIKSLMANT ELDSNFKNVLEDVYRYSQSGISSKSIDSHIQEHQNSLSQWVEQMDSYS*" gene 2925993..2926271 /gene="ytzH" /locus_tag="BSU_29910" /old_locus_tag="BSU29910" S_feature 2926272..2926442 /Source="Nicolas_S_feature" /locus_tag="new_3060674_3060844" /HighExp="S5, S7, S8, S6, S4, BT, C30, nit, ferm, G/S" /AntisenseName="ytmP" /AntisenseCor="-0.32108027439793901" /AntisenseRegPval="-7.1" /CDS_PredictionProba="NA" /TUshortSig="SigGF" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1147" CDS complement(2926272..2926886) /gene="ytmP" /locus_tag="BSU_29920" /old_locus_tag="BSU29920" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 9026440, 11545674; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative kinase/phosphotransferase" /protein_id="NP_390870.2" /db_xref="EnsemblGenomes-Gn:BSU29920" /db_xref="EnsemblGenomes-Tr:CAB14970" /db_xref="GOA:C0SPC1" /db_xref="InterPro:IPR002575" /db_xref="InterPro:IPR011009" /db_xref="SubtiList:BG13889" /db_xref="UniProtKB/Swiss-Prot:C0SPC1" /translation="MENGDVITAQHWMTGRELKPKDMSGRPVAELLRKIHTSKALLDM LKRLGKEPLNPGALLSQLKQAVFAVQQSSPLIQEGIKYLEEHLHEVHFGEKVVCHCDV NHNNWLLSEDNQLYLIDWDGAMIADPAMDLGPLLYHYVEKPAWESWLSMYGIELTESL RLRMAWYVLSETITFIAWHKAKGNDKEFHDAMEELHILMKRIVD*" gene complement(2926272..2926886) /gene="ytmP" /locus_tag="BSU_29920" /old_locus_tag="BSU29920" downshifts 2926420 /Source="Nicolas_upshifts" /id="D1543" /incds=1 /nref=4 /ntot=35 /MaxReadThrough="2.54837" /MaxDrop="3.82368" /score="-4.89809956" /energy="-11.3" /TU="NA" /idTUdmin="U2322" /TUdmin=0 /isTUend="TRUE" S_feature complement(2926887..2927222) /Source="Nicolas_S_feature" /locus_tag="new_3061289_3061624_c" /HighExp="T1.30H, M9-stat, T2.30H, T3.0H, UNK1, B60, T2.0H, T3.30H, T1.0H, GM-0.2" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.999" /TUlongSig="SigD, SigA" /TUlongPSig="1, 0.992" /label="S1148" promotor_-10 complement(2927214..2927233) /Source="Nicolas_upshift_promotors" /id="U2323" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.855144855144855" /psig="0.999000999001" /xcortree=2288 /SigmaFactorBS="atatttagcatcagatcttaagagtttTGCTTGACgaagttt gtgctatAGCGCTAAAATTTAAAGGACggctattgattagcatatgagactctcaata g" /listShort="S1148, ytmP, S1146, trmB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2927222) /Source="Nicolas_upshifts" /id="U2323" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.855144855144855" /psig="0.999000999001" /xcortree=2288 /SigmaFactorBS="atatttagcatcagatcttaagagtttTGCTTGACgaagttt gtgctatAGCGCTAAAATTTAAAGGACggctattgattagcatatgagactctcaata g" /listShort="S1148, ytmP, S1146, trmB" /GFF_Attribute="listLong" promotor_-35 complement(2927248..2927255) /Source="Nicolas_upshift_promotors" /id="U2323" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.855144855144855" /psig="0.999000999001" /xcortree=2288 /SigmaFactorBS="atatttagcatcagatcttaagagtttTGCTTGACgaagttt gtgctatAGCGCTAAAATTTAAAGGACggctattgattagcatatgagactctcaata g" /listShort="S1148, ytmP, S1146, trmB" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2927249..2929405) /gene="amyX" /locus_tag="BSU_29930" /old_locus_tag="BSU29930" /EC_number="3.2.1.41" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:9453151, 16582490, 19465663, 23973973" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9453151, 16582490, 19465663, 23973973; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="pullulanase" /protein_id="NP_390871.2" /db_xref="EnsemblGenomes-Gn:BSU29930" /db_xref="EnsemblGenomes-Tr:CAB14971" /db_xref="GOA:C0SPA0" /db_xref="InterPro:IPR004193" /db_xref="InterPro:IPR006047" /db_xref="InterPro:IPR011840" /db_xref="InterPro:IPR013783" /db_xref="InterPro:IPR014756" /db_xref="InterPro:IPR017853" /db_xref="PDB:2E8Y" /db_xref="PDB:2E8Z" /db_xref="PDB:2E9B" /db_xref="SubtiList:BG12566" /db_xref="UniProtKB/Swiss-Prot:C0SPA0" /translation="MVSIRRSFEAYVDDMNIITVLIPAEQKEIMTPPFRLETEITDFP LAVREEYSLEAKYKYVCVSDHPVTFGKIHCVRASSGHKTDLQIGAVIRTAAFDDEFYY DGELGAVYTADHTVFKVWAPAATSAAVKLSHPNKSGRTFQMTRLEKGVYAVTVTGDLH GYEYLFCICNNSEWMETVDQYAKAVTVNGEKGVVLRPDQMKWTAPLKPFSHPVDAVIY ETHLRDFSIHENSGMINKGKYLALTETDTQTANGSSSGLAYVKELGVTHVELLPVNDF AGVDEEKPLDAYNWGYNPLHFFAPEGSYASNPHDPQTRKTELKQMINTLHQHGLRVIL DVVFNHVYKRENSPFEKTVPGYFFRHDECGMPSNGTGVGNDIASERRMARKFIADCVV YWLEEYNVDGFRFDLLGILDIDTVLYMKEKATKAKPGILLFGEGWDLATPLPHEQKAA LANAPRMPGIGFFNDMFRDAVKGNTFHLKATGFALGNGESAQAVMHGIAGSSGWKALA PIVPEPSQSINYVESHDNHTFWDKMSFALPQENDSRKRSRQRLAAAIILLAQGVPFIH SGQEFFRTKQGVENSYQSSDSINQLDWDRRETFKEDVHYIRRLISLRKAHPAFRLRSA ADIQRHLECLTLKEHLIAYRLYDLDEVDEWKDIIVIHHASPDSVEWRLPNDIPYRLLC DPSGFQEDPTEIKKTVAVNGIGTVILYLASDLKSFA*" gene complement(2927249..2929405) /gene="amyX" /locus_tag="BSU_29930" /old_locus_tag="BSU29930" CDS complement(2929431..2930360) /gene="ytlR" /locus_tag="BSU_29940" /old_locus_tag="BSU29940" /EC_number="2.7.1.-" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative phospholipid kinase" /protein_id="NP_390872.1" /db_xref="EnsemblGenomes-Gn:BSU29940" /db_xref="EnsemblGenomes-Tr:CAB14972" /db_xref="GOA:O34799" /db_xref="InterPro:IPR001206" /db_xref="InterPro:IPR005218" /db_xref="InterPro:IPR016064" /db_xref="InterPro:IPR017438" /db_xref="SubtiList:BG13880" /db_xref="UniProtKB/Swiss-Prot:O34799" /translation="MSHWFFIINPTAGHRNGLRVWKSIQKELIKRKVEHRSFLTEHPG HAEVLARQISTIQEYKLKRLIVIGGDGTMHEVVNGLKDVDDIELSFVPAGAYNDFSRG FSIKKIDLIQEIKKVKRPLTRTFHLGSVNFLQDKSQILYFMNHIGIGFDAYVNKKAME FPLRRVFLFLRLRFLVYPLSHLHASATFKPFTLACTTEDETREFHDVWFAVVSNHPFY GGGMKAAPLANPREKTFDIVIVENQPFLKKYWLLCLMAFGKHTKMDGVTMFKAKDITF YTKDKIPFHADGEIMGTTPFRLASSPSPLRIKT*" gene complement(2929431..2930360) /gene="ytlR" /locus_tag="BSU_29940" /old_locus_tag="BSU29940" CDS complement(2930409..2931323) /gene="ytlQ" /locus_tag="BSU_29950" /old_locus_tag="BSU29950" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative hydrolase" /protein_id="NP_390873.1" /db_xref="EnsemblGenomes-Gn:BSU29950" /db_xref="EnsemblGenomes-Tr:CAB14973" /db_xref="InterPro:IPR012397" /db_xref="SubtiList:BG13879" /db_xref="UniProtKB/Swiss-Prot:O34471" /translation="MAQIIKIHDYISRYELDPYHYINQFVRLKKERWLSLVEAAERQH EERQASAEEPEPVQKRKKFSLKRRKEEIKADIQEERHQWFEDEEDIHVRLPKSRVALA SFYKRHLYDFQLKWASSTLSEISQLSNQVKQDRILRYLTQQLPDSYFIMYKPVLKIQQ AAVELSIVIISPLEIYCVSFLEAEEDSVYIGSKNRFWDKKTASQTASVLNPGLSLFRT DSVVSKIVKEKQAEIPVRKLLLSRTSYIDYPEPPYGLEIADKRSAEEWIERQKKNTAP IKHHQVKAAKALLSYCMSDSYRRQEWLE*" gene complement(2930409..2931323) /gene="ytlQ" /locus_tag="BSU_29950" /old_locus_tag="BSU29950" promotor_-10 complement(2931086..2931104) /Source="Nicolas_upshift_promotors" /id="U2324" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2820 /SigmaFactorBS="tgcagaaacgaaaaaaattttcattgaaaaGAAGAAAagaag agataaaaGCCGATATACAAGAAGAGAgacaccaatggtttgaggacgaagaagatat t" /listShort="ytlR, amyX" /listLong="S1148, ytmP, S1146, trmB" /label="promotor_-10" upshifts complement(2931094) /Source="Nicolas_upshifts" /id="U2324" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2820 /SigmaFactorBS="tgcagaaacgaaaaaaattttcattgaaaaGAAGAAAagaag agataaaaGCCGATATACAAGAAGAGAgacaccaatggtttgaggacgaagaagatat t" /listShort="ytlR, amyX" /listLong="S1148, ytmP, S1146, trmB" promotor_-35 complement(2931118..2931124) /Source="Nicolas_upshift_promotors" /id="U2324" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2820 /SigmaFactorBS="tgcagaaacgaaaaaaattttcattgaaaaGAAGAAAagaag agataaaaGCCGATATACAAGAAGAGAgacaccaatggtttgaggacgaagaagatat t" /listShort="ytlR, amyX" /listLong="S1148, ytmP, S1146, trmB" /label="promotor_-35" CDS complement(2931349..2931900) /gene="ytlP" /locus_tag="BSU_29960" /old_locus_tag="BSU29960" /EC_number="3.1.4.-" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 17012785; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative RNA 2',3'-cyclic phosphodiesterase" /protein_id="NP_390874.1" /db_xref="EnsemblGenomes-Gn:BSU29960" /db_xref="EnsemblGenomes-Tr:CAB14974" /db_xref="GOA:O34570" /db_xref="InterPro:IPR004175" /db_xref="InterPro:IPR009097" /db_xref="SubtiList:BG13878" /db_xref="UniProtKB/Swiss-Prot:O34570" /translation="MPDIRPHYFIGVPIPEGIANPIYQAAKNEPILTFQKWVHPLDYH ITLIFLGAADETQIKKLEGSLAEIASEIDPFSIKFGKIDVFGDRRKPRVLHLEPKKNK TLDRLREHTKQAVLQAGFQVEKRPYHPHMTLARKWTGEDGFPAHVPFESGEVSMMAER FSLFQIHLNQSPKYEEIFKFQLS*" gene complement(2931349..2931900) /gene="ytlP" /locus_tag="BSU_29960" /old_locus_tag="BSU29960" misc_feature 2931763..2931782 /Source="Nicolas_upshift_promotors" /id="U2325" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.962037962037962" /psig="0.996003996003996" /xcortree=2127 /SigmaFactorBS="tagcgaaccttcaagcttctttatttgtgtctcatccgccgc tccgagaaaaattaaCGTGATATGATAGTCAAGCGggtgcacccatttttgaaacgtc a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 2931766 /Source="Nicolas_upshifts" /id="U2325" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.962037962037962" /psig="0.996003996003996" /xcortree=2127 /SigmaFactorBS="tagcgaaccttcaagcttctttatttgtgtctcatccgccgc tccgagaaaaattaaCGTGATATGATAGTCAAGCGggtgcacccatttttgaaacgtc a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 complement(2931923..2931942) /Source="Nicolas_upshift_promotors" /id="U2326" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.423576423576424" /psig="0.992007992007992" /xcortree=2211 /SigmaFactorBS="cgtttgtgcgagagtgttttcatacactgttcctCTATccgc acagcctctttATTGATAAAATAATAGCTGTcaaagaagggagtgtcagacggatgcc a" /listShort="ytlP, ytlQ, ytlR, amyX" /listLong="S1148, ytmP, S1146, trmB" /label="promotor_-10" upshifts complement(2931935) /Source="Nicolas_upshifts" /id="U2326" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.423576423576424" /psig="0.992007992007992" /xcortree=2211 /SigmaFactorBS="cgtttgtgcgagagtgttttcatacactgttcctCTATccgc acagcctctttATTGATAAAATAATAGCTGTcaaagaagggagtgtcagacggatgcc a" /listShort="ytlP, ytlQ, ytlR, amyX" /listLong="S1148, ytmP, S1146, trmB" promotor_-35 complement(2931958..2931961) /Source="Nicolas_upshift_promotors" /id="U2326" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.423576423576424" /psig="0.992007992007992" /xcortree=2211 /SigmaFactorBS="cgtttgtgcgagagtgttttcatacactgttcctCTATccgc acagcctctttATTGATAAAATAATAGCTGTcaaagaagggagtgtcagacggatgcc a" /listShort="ytlP, ytlQ, ytlR, amyX" /listLong="S1148, ytmP, S1146, trmB" /label="promotor_-35" promotor_-35 2931983..2931990 /Source="Nicolas_upshift_promotors" /id="U2327" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.974025974025974" /psig="0.999000999001" /xcortree=1889 /SigmaFactorBS="ggctgtgcggatagaggaacagtgtatgaaaacacTCTCGCA CaaacgtttatTATGTTAGGATATTATATGAcacttgttttattcagaaaggaatgac a" /listShort="ytkP" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2932001..2932020 /Source="Nicolas_upshift_promotors" /id="U2327" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.974025974025974" /psig="0.999000999001" /xcortree=1889 /SigmaFactorBS="ggctgtgcggatagaggaacagtgtatgaaaacacTCTCGCA CaaacgtttatTATGTTAGGATATTATATGAcacttgttttattcagaaaggaatgac a" /listShort="ytkP" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-10 complement(2932004..2932015) /Source="Nicolas_upshift_promotors" /id="U2328" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.98901098901099" /psig="0.98901098901099" /xcortree=895 /SigmaFactorBS="atcagctgtgtttgcaacgattttcaacattgtcattccttt cTGAATAAaacaagtgtcataTAATATCCTAACataataaacgtttgtgcgagagtgt t" /listShort="ytlP, ytlQ, ytlR, amyX" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2932008 /Source="Nicolas_upshifts" /id="U2327" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.974025974025974" /psig="0.999000999001" /xcortree=1889 /SigmaFactorBS="ggctgtgcggatagaggaacagtgtatgaaaacacTCTCGCA CaaacgtttatTATGTTAGGATATTATATGAcacttgttttattcagaaaggaatgac a" /listShort="ytkP" /GFF_Attribute="listLong" upshifts complement(2932018) /Source="Nicolas_upshifts" /id="U2328" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.98901098901099" /psig="0.98901098901099" /xcortree=895 /SigmaFactorBS="atcagctgtgtttgcaacgattttcaacattgtcattccttt cTGAATAAaacaagtgtcataTAATATCCTAACataataaacgtttgtgcgagagtgt t" /listShort="ytlP, ytlQ, ytlR, amyX" /GFF_Attribute="listLong" promotor_-35 complement(2932029..2932035) /Source="Nicolas_upshift_promotors" /id="U2328" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.98901098901099" /psig="0.98901098901099" /xcortree=895 /SigmaFactorBS="atcagctgtgtttgcaacgattttcaacattgtcattccttt cTGAATAAaacaagtgtcataTAATATCCTAACataataaacgtttgtgcgagagtgt t" /listShort="ytlP, ytlQ, ytlR, amyX" /GFF_Attribute="listLong" /label="promotor_-35" CDS 2932049..2932984 /gene="ytkP" /locus_tag="BSU_29970" /old_locus_tag="BSU29970" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 12193636, 16267287; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative cysteine synthase-like enzyme" /protein_id="NP_390875.1" /db_xref="EnsemblGenomes-Gn:BSU29970" /db_xref="EnsemblGenomes-Tr:CAB14975" /db_xref="GOA:O34476" /db_xref="InterPro:IPR001216" /db_xref="InterPro:IPR001926" /db_xref="InterPro:IPR005856" /db_xref="InterPro:IPR005859" /db_xref="InterPro:IPR036052" /db_xref="SubtiList:BG13872" /db_xref="UniProtKB/Swiss-Prot:O34476" /translation="MLKIVANTADLIGDTPLVRLNRLQPENAAQVYLKLEFFNPSGSV KDRAAYQMIIEAEQNGLLKPGSVIIEPTSGNTGIGLAMNAAARGYKAILVMPDTMTKE RINLLKAYGAEVVLTPGEERMPGSIKKAKELAEQIPNSYIPMQFDNTANPDAHRKTTA PEIARAIEEIGKPLGAFVASSGTGGTITGTGEALKELFPDITVHVVEPAGSPVLSGGK PGAHKLVGTSPGFIPPILNEDVYDEIIKISDEDAYTTTRRLAAEEGILVGPSSGAACF AAIETAKRLSPDKVVVCMTADTGERYLSTDLWSFI*" gene 2932049..2932984 /gene="ytkP" /locus_tag="BSU_29970" /old_locus_tag="BSU29970" downshifts 2932960 /Source="Nicolas_upshifts" /id="D1544" /incds=0 /nref=74 /ntot=225 /MaxReadThrough="2.5873" /MaxDrop="4.59197" /score="29.2734118" /energy="-18.2" /TU="NA" /idTUdmin="U2327" /TUdmin="-16" /isTUend="TRUE" CDS complement(2933018..2934409) /gene="ytjP" /locus_tag="BSU_29980" /old_locus_tag="BSU29980" /EC_number="3.5.-.-" /EC_number="3.4.13.-" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 7528082, 27435445; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative promiscuous peptidase/deacylase" /protein_id="NP_390876.1" /db_xref="EnsemblGenomes-Gn:BSU29980" /db_xref="EnsemblGenomes-Tr:CAB14976" /db_xref="GOA:O34944" /db_xref="InterPro:IPR001261" /db_xref="InterPro:IPR002933" /db_xref="InterPro:IPR010964" /db_xref="InterPro:IPR036264" /db_xref="SubtiList:BG13867" /db_xref="UniProtKB/Swiss-Prot:O34944" /translation="MNWEVEVIRKKEDLIRDTQEFLRINSVMDETTAGPGKPFGEGVN ASLTSLLELGEKEGFTTKNLDGFAGHIEWGEGDDIIGVLCHVDVVPPGDGWTSDPFSA EIRNGRIYARGAIDDKGPTMAAFYALKIVKDMNLPLSKRVRMIIGTDEESDWRCVEHY FKHEEMPTMGFAPDADFPIINAEKGIIDASLLIPHRPNQAEPKAVLVSFQSGLRLNMV PDAAEAVIEGPKNEEILSSFKDMLRTTDQKGEAAIENGQLILRMYGLSCHAMEPNNGI NAGILLCEFLQQTELDDAGKRFVQVVTDKFSGDTRGKKLDIDCEDEISGELTLNVGTL RYKEGQGGELGINIRYPVTAESKVIRDTFESASEFELGEFKDSKPHHVSADHPLVKTL QKVYEGQLGKKADLISIGGGTYARSLKAGVAFGPLFPGRPDSAHQKDEYIEIDDLLRS TALYAQAIYELAK*" gene complement(2933018..2934409) /gene="ytjP" /locus_tag="BSU_29980" /old_locus_tag="BSU29980" downshifts complement(2933030) /Source="Nicolas_upshifts" /id="D1545" /incds=0 /nref=63 /ntot=240 /MaxReadThrough="3.38616" /MaxDrop="3.73023" /score="23.9099234" /energy="-14.4" /TU="U2330" /idTUdmin="U2330" /TUdmin="-330" /isTUend="FALSE" S_feature complement(2934410..2934850) /Source="Nicolas_S_feature" /locus_tag="new_3068812_3069252_c" /HighExp="Etha, Salt, M40t90, Lbtran, T1.30H, M0t90, Lbstat, T1.0H, T0.30H, LBGstat" /AntisenseName="pbuO" /AntisenseCor="-0.324692399913451" /AntisenseRegPval="-7.3" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.997" /TUlongSig="NA" /TUlongPSig="NA" /label="S1149" promotor_-35 2934436..2934441 /Source="Nicolas_upshift_promotors" /id="U2329" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.403596403596404" /psig="0.994005994005994" /xcortree=2633 /SigmaFactorBS="ataatgatcccctttccgcaagaaatgaCTTGCAaaaaccaa ataaaACGAATAATATTAATGGTGTtttgttaaaacgttcgtaattggaggatactat g" /listShort="pbuO" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2934455..2934474 /Source="Nicolas_upshift_promotors" /id="U2329" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.403596403596404" /psig="0.994005994005994" /xcortree=2633 /SigmaFactorBS="ataatgatcccctttccgcaagaaatgaCTTGCAaaaaccaa ataaaACGAATAATATTAATGGTGTtttgttaaaacgttcgtaattggaggatactat g" /listShort="pbuO" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2934468 /Source="Nicolas_upshifts" /id="U2329" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.403596403596404" /psig="0.994005994005994" /xcortree=2633 /SigmaFactorBS="ataatgatcccctttccgcaagaaatgaCTTGCAaaaaccaa ataaaACGAATAATATTAATGGTGTtttgttaaaacgttcgtaattggaggatactat g" /listShort="pbuO" /GFF_Attribute="listLong" CDS 2934506..2935804 /gene="pbuO" /locus_tag="BSU_29990" /old_locus_tag="BSU29990" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:11591660, 12923093, 15849754, 16850406, 19446032, 28583948" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11591660, 12923093, 15849754, 16850406, 19446032, 28583948; Product type t : transporter" /codon_start=1 /transl_table=11 /product="hypoxanthine/guanine permease" /protein_id="NP_390877.1" /db_xref="EnsemblGenomes-Gn:BSU29990" /db_xref="EnsemblGenomes-Tr:CAB14977" /db_xref="GOA:O34978" /db_xref="InterPro:IPR006043" /db_xref="InterPro:IPR026033" /db_xref="SubtiList:BG13864" /db_xref="UniProtKB/Swiss-Prot:O34978" /translation="MFHLKEQQTSIKQEIIAGLTTFFTMVYIVVVNPVILANAGVPFD QVFTATIIASIVGTLWMALAANYPIAIAPGMGLNAYLAFHVVSASDGGITYATAFSAV FTAGVLFIILSLTPLRKQLIEAIPNNLKYGITTGIGLFIAFIGLRQAGIVAADESNLV TLGNLHSPGVILTLVGLLISVVLMVLNVSGALFIGMAATALIAFFTGQLHFSKGFMSL PHLPEGLMISNPFTAFGDVIHHGLYAVVFSFLLVTIFDTTGTMIGVAEQAGLMKNNKL PNVRKALLADSTATTVGAVFGTSPTTAFIESSAGVAAGGRTGLTALTVAVMFAASMFF SPLVSALSGIAAITSPALIIVGSLMMGSVSNMNWKEMDEAFPAFLVILAMPLTSSIST GIALGFISYPIVKAARGKWREIHPLVIVFAILFFIQLFIL*" gene 2934506..2935804 /gene="pbuO" /locus_tag="BSU_29990" /old_locus_tag="BSU29990" promotor_-10 complement(2934827..2934846) /Source="Nicolas_upshift_promotors" /id="U2330" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.5004995004995" /psig="0.997002997002997" /xcortree=3182 /SigmaFactorBS="tgttgtgatcccgtattttaaattgtttggaatcgcttctat aAGTTGTTttcttaaaggcgttAACGATAGAATAATGAAGAGaacccctgctgtaaat a" /listShort="S1149, ytjP" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2934850) /Source="Nicolas_upshifts" /id="U2330" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.5004995004995" /psig="0.997002997002997" /xcortree=3182 /SigmaFactorBS="tgttgtgatcccgtattttaaattgtttggaatcgcttctat aAGTTGTTttcttaaaggcgttAACGATAGAATAATGAAGAGaacccctgctgtaaat a" /listShort="S1149, ytjP" /GFF_Attribute="listLong" promotor_-35 complement(2934861..2934867) /Source="Nicolas_upshift_promotors" /id="U2330" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.5004995004995" /psig="0.997002997002997" /xcortree=3182 /SigmaFactorBS="tgttgtgatcccgtattttaaattgtttggaatcgcttctat aAGTTGTTttcttaaaggcgttAACGATAGAATAATGAAGAGaacccctgctgtaaat a" /listShort="S1149, ytjP" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 2935791 /Source="Nicolas_upshifts" /id="D1546" /incds=0 /nref=43 /ntot=178 /MaxReadThrough="2.37859" /MaxDrop="5.35341" /score="16.9979166" /energy="-10.2" /TU="NA" /idTUdmin="U2329" /TUdmin="-1" /isTUend="TRUE" CDS complement(2935844..2937001) /gene="ythQ" /locus_tag="BSU_30000" /old_locus_tag="BSU30000" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative ABC transporter (permease)" /protein_id="NP_390878.1" /db_xref="EnsemblGenomes-Gn:BSU30000" /db_xref="EnsemblGenomes-Tr:CAB14978" /db_xref="GOA:O35029" /db_xref="InterPro:IPR010288" /db_xref="SubtiList:BG13861" /db_xref="UniProtKB/Swiss-Prot:O35029" /translation="MNGRTLFFRRLFDYYKYQFKVLHAVIDWTVALYIVLPAIAFVIY QYIDLMNGRGLLYEWSEVAEWRWLYAVCVLIMFTGSIRTFLMEADKVFLLQKKEIIYQ LKRYALLYSFLATLAKWLLLFFIVLPLISHSVLITFAESTALLCYLFGLHIFFLSLKQ DRIRKPRSISRWIGDTLVRAILFAGSAILIVFTERHLLALFGILFLFFSVIRSLKKTA SFTAFEAEVTEEKKSRLALAGLVMMMSQEAGMPKVKDRMRRKPLLYRNSKRIFKRRTI CTGYKELFFKVMLRNGEYARQMYMLLSAFTVLIFVSPIWLKVIALLVYTGVCRYILTL IFDKVMDAPFLIGTDKESDEYYRARKSCINILHYAFAACCFLAAAVSLLFT*" gene complement(2935844..2937001) /gene="ythQ" /locus_tag="BSU_30000" /old_locus_tag="BSU30000" downshifts complement(2935869) /Source="Nicolas_upshifts" /id="D1547" /incds=0 /nref=1 /ntot=153 /MaxReadThrough="3.07175" /MaxDrop="3.89104" /score="19.8243425" /energy="-11.2" /TU="NA" /idTUdmin="U2332" /TUdmin=0 /isTUend="TRUE" promotor_-35 2936117..2936122 /Source="Nicolas_upshift_promotors" /id="U2331" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.992007992007992" /psig="0.992007992007992" /xcortree=1395 /SigmaFactorBS="gtgaaagctgacagtagcatgtacatctgcctTGCATActcg ccattcctcaGCATAACTTTAAAAAACAActccttatagcctgtgcagatcgttcgtc t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2936137..2936155 /Source="Nicolas_upshift_promotors" /id="U2331" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.992007992007992" /psig="0.992007992007992" /xcortree=1395 /SigmaFactorBS="gtgaaagctgacagtagcatgtacatctgcctTGCATActcg ccattcctcaGCATAACTTTAAAAAACAActccttatagcctgtgcagatcgttcgtc t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2936145 /Source="Nicolas_upshifts" /id="U2331" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.992007992007992" /psig="0.992007992007992" /xcortree=1395 /SigmaFactorBS="gtgaaagctgacagtagcatgtacatctgcctTGCATActcg ccattcctcaGCATAACTTTAAAAAACAActccttatagcctgtgcagatcgttcgtc t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" CDS complement(2936998..2937708) /gene="ythP" /locus_tag="BSU_30010" /old_locus_tag="BSU30010" /EC_number="3.6.3.-" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative ABC transporter (ATP-binding protein)" /protein_id="NP_390879.1" /db_xref="EnsemblGenomes-Gn:BSU30010" /db_xref="EnsemblGenomes-Tr:CAB14979" /db_xref="GOA:O34977" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR017871" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG13860" /db_xref="UniProtKB/Swiss-Prot:O34977" /translation="MTNLLEASIEQAGYTSRKKVLTDVFLEVRKGELVGLIGANGAGK STAIKAILGLSEDFKGHIAWNDCSFAYIPEHPSFYEELTLWEHLDLISTLHGIEESEF AHRAQSLLQTFSLDHVKHELPVTFSKGMQQKLMLIQAFLSKPDMYVIDEPFIGLDPIS TKRFVDMLKAEKERGAGILMCTHVLDTAEKICDRFYMIEKGSLFLQGTLKDVQDKTGL EGQSLLDCFYKAVQGDRL*" gene complement(2936998..2937708) /gene="ythP" /locus_tag="BSU_30010" /old_locus_tag="BSU30010" promotor_-10 complement(2937722..2937737) /Source="Nicolas_upshift_promotors" /id="U2332" /multdbtbs="SigW" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1669 /SigmaFactorBS="ttggattactatgtatttcggctcaatattattatggttaaA GAAACTTTTtttattctattTCGTAGTAAATTTTGGaggtgagtgagttttgacaaat t" /listShort="ythP, ythQ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2937739) /Source="Nicolas_upshifts" /id="U2332" /multdbtbs="SigW" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1669 /SigmaFactorBS="ttggattactatgtatttcggctcaatattattatggttaaA GAAACTTTTtttattctattTCGTAGTAAATTTTGGaggtgagtgagttttgacaaat t" /listShort="ythP, ythQ" /GFF_Attribute="listLong" promotor_-35 complement(2937749..2937758) /Source="Nicolas_upshift_promotors" /id="U2332" /multdbtbs="SigW" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1669 /SigmaFactorBS="ttggattactatgtatttcggctcaatattattatggttaaA GAAACTTTTtttattctattTCGTAGTAAATTTTGGaggtgagtgagttttgacaaat t" /listShort="ythP, ythQ" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 2937765..2937766 /Source="Nicolas_upshift_promotors" /id="U2333" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.583416583416583" /psig="0.583416583416583" /xcortree=956 /SigmaFactorBS="acctccaaaatttactacgaaatagaataaaaaaagtttctt taaccATaataatattgagccgaaatACATAGTAATCcaacaaggatggctgcccaac g" /listShort="S1150, S1151, ytzE" /GFF_Attribute="listLong" /label="promotor_-35" S_feature 2937778..2937883 /Source="Nicolas_S_feature" /locus_tag="new_3072180_3072285" /HighExp="S5, S4, S3, S8, S7, S6, G/S, Pyr, T5.0H, BT" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigEF" /TUshortPSig="0.583" /TUlongSig="NA" /TUlongPSig="NA" /label="S1150" upshifts 2937778 /Source="Nicolas_upshifts" /id="U2333" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.583416583416583" /psig="0.583416583416583" /xcortree=956 /SigmaFactorBS="acctccaaaatttactacgaaatagaataaaaaaagtttctt taaccATaataatattgagccgaaatACATAGTAATCcaacaaggatggctgcccaac g" /listShort="S1150, S1151, ytzE" /GFF_Attribute="listLong" promotor_-10 2937786..2937796 /Source="Nicolas_upshift_promotors" /id="U2333" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.583416583416583" /psig="0.583416583416583" /xcortree=956 /SigmaFactorBS="acctccaaaatttactacgaaatagaataaaaaaagtttctt taaccATaataatattgagccgaaatACATAGTAATCcaacaaggatggctgcccaac g" /listShort="S1150, S1151, ytzE" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 2937849..2937855 /Source="Nicolas_upshift_promotors" /id="U2334" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.497502497502497" /psig=1 /xcortree=399 /SigmaFactorBS="tggaaaaaattaataggagttatcCCTAGATtcatcactgca ataTCGTGTATAATGAGGGCGAAttattttaacaattacagatgtctgcctttgttgc t" /listShort="S1151, ytzE" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2937870..2937889 /Source="Nicolas_upshift_promotors" /id="U2334" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.497502497502497" /psig=1 /xcortree=399 /SigmaFactorBS="tggaaaaaattaataggagttatcCCTAGATtcatcactgca ataTCGTGTATAATGAGGGCGAAttattttaacaattacagatgtctgcctttgttgc t" /listShort="S1151, ytzE" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 2937885..2937998 /Source="Nicolas_S_feature" /locus_tag="new_3072287_3072400" /HighExp="S4, S5, M0t90, S3, Etha, M9-stat, M40t90, LPhT, Heat, HiOs" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigEF" /TUshortPSig="1, 0.583" /TUlongSig="NA" /TUlongPSig="NA" /label="S1151" upshifts 2937885 /Source="Nicolas_upshifts" /id="U2334" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.497502497502497" /psig=1 /xcortree=399 /SigmaFactorBS="tggaaaaaattaataggagttatcCCTAGATtcatcactgca ataTCGTGTATAATGAGGGCGAAttattttaacaattacagatgtctgcctttgttgc t" /listShort="S1151, ytzE" /GFF_Attribute="listLong" CDS 2937999..2938220 /gene="ytzE" /locus_tag="BSU_30020" /old_locus_tag="BSU30020" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 12618461; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative transcriptional regulator (DeoR family)" /protein_id="NP_390880.1" /db_xref="EnsemblGenomes-Gn:BSU30020" /db_xref="EnsemblGenomes-Tr:CAB14980" /db_xref="GOA:O32067" /db_xref="InterPro:IPR001034" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG13939" /db_xref="UniProtKB/Swiss-Prot:O32067" /translation="MKPSTNRMLTRIKSVYMFIQEKGLVTTQELVDEFGITPRTIQRD LNVLAYNDLVHSPSRGKWETTRKKVKITS*" gene 2937999..2938220 /gene="ytzE" /locus_tag="BSU_30020" /old_locus_tag="BSU30020" downshifts 2938203 /Source="Nicolas_upshifts" /id="D1548" /incds=0 /nref=166 /ntot=259 /MaxReadThrough="4.38243" /MaxDrop="4.90218" /score="20.9755494" /energy="-13.5" /TU="U2333,U2334" /idTUdmin="U2333" /TUdmin="-54" /isTUend="FALSE" downshifts 2938272 /Source="Nicolas_upshifts" /id="D1549" /incds=0 /nref=44 /ntot=172 /MaxReadThrough="-0.189589999999999" /MaxDrop="6.00369" /score="20.9755494" /energy="-13.5" /TU="NA" /idTUdmin="U2334" /TUdmin="-7" /isTUend="TRUE" CDS complement(2938341..2939060) /gene="rsuA" /locus_tag="BSU_30035" /old_locus_tag="BSU30035" /EC_number="4.2.1.70" /function="16.6: Maintain" /function="16.8: Protect" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 11953756, 16511038; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="16S rRNA pseudouridylate 516 synthase" /protein_id="NP_390882.2" /db_xref="EnsemblGenomes-Gn:BSU30035" /db_xref="EnsemblGenomes-Tr:CAB14982" /db_xref="GOA:O32068" /db_xref="InterPro:IPR000748" /db_xref="InterPro:IPR002942" /db_xref="InterPro:IPR006145" /db_xref="InterPro:IPR018496" /db_xref="InterPro:IPR020103" /db_xref="InterPro:IPR036986" /db_xref="SubtiList:BG13941" /db_xref="UniProtKB/Swiss-Prot:O32068" /translation="MRLDKLLANSGYGSRKEVKAVVKAGAVMIDGKPAKDVKEHVDPD TQEVTVYGEPVDYREFIYLMMNKPQGVLSATEDSRQQTVVDLLTPEEMRFEPFPAGRL DKDTEGFLLLTNDGQLAHRLLSPKKHVPKTYEVHLKSQISREDISDLETGVYIEGGYK TKPAKAEIKTNDSGNTVIYLTITEGKYHQVKQMAKAVGNEVVYLKRLSMGRVSLDPAL APGEYRELTEEELHLLNEPQA*" gene complement(2938341..2939060) /gene="rsuA" /locus_tag="BSU_30035" /old_locus_tag="BSU30035" downshifts complement(2938355) /Source="Nicolas_upshifts" /id="D1550" /incds=0 /nref=1 /ntot=49 /MaxReadThrough="0.79865" /MaxDrop="2.6873" /score="21.6808891" /energy="-13.5" /TU="NA" /idTUdmin="U2335" /TUdmin=154 /isTUend="FALSE" downshifts complement(2939126) /Source="Nicolas_upshifts" /id="D1551" /incds=0 /nref=1 /ntot=76 /MaxReadThrough="4.50848" /MaxDrop="2.99899" /score="8.79816042" /energy="-9.5" /TU="U2335" /idTUdmin="U2335" /TUdmin="-617" /isTUend="FALSE" CDS complement(2939129..2940763) /gene="murJ" /locus_tag="BSU_30050" /old_locus_tag="BSU30050" /function="16.5: Explore" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:11254558, 15044829, 15849754, 16850406, 19648239, 25918422, 27537185" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11254558, 15044829, 15849754, 16850406, 19648239, 25918422, 27537185; Product type t: transporter" /codon_start=1 /transl_table=11 /product="lipid II flippase" /protein_id="NP_390883.1" /db_xref="EnsemblGenomes-Gn:BSU30050" /db_xref="EnsemblGenomes-Tr:CAB14983" /db_xref="GOA:O34674" /db_xref="InterPro:IPR002797" /db_xref="InterPro:IPR024923" /db_xref="InterPro:IPR029303" /db_xref="SubtiList:BG13856" /db_xref="UniProtKB/Swiss-Prot:O34674" /translation="MSSKLLRGTFVLTLGTYISRILGMVYLIPFSIMVGATGGALFQY GYNQYTLFLNIATMGFPAAVSKFVSKYNSKGDYETSRKMLKAGMSVMLVTGMIAFFIL YLSAPMFAEISLGGKDNNGLTIDHVVYVIRMVSLALLVVPIMSLVRGFFQGHQMMGPT AVSQVVEQIVRIIFLLSATFLILKVFNGGLVIAVGYATFAALIGAFGGLVVLYIYWNK RKGSLLAMMPNTGPTANLSYKKMFFELFSYAAPYVFVGLAIPLYNYIDTNTFNKAMIE AGHQAISQDMLAILTLYVQKLVMIPVSLATAFGLTLIPTITESFTSGNYKLLNQQINQ TMQTILFLIIPAVVGISLLSGPTYTFFYGSESLHPELGANILLWYSPVAILFSLFTVN AAILQGINKQKFAVVSLVIGVVIKLVLNVPLIKLMQADGAILATALGYIASLLYGFIM IKRHAGYSYKILVKRTVLMLVLSAIMGIAVKIVQWVLGFFISYQDGQMQAAIVVVIAA AVGGAVYLYCGYRLGFLQKILGRRLPGFFRKGRHAG*" gene complement(2939129..2940763) /gene="murJ" /locus_tag="BSU_30050" /old_locus_tag="BSU30050" misc_feature complement(2940795..2940814) /Source="Nicolas_upshift_promotors" /id="U2335" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.631368631368631" /psig="0.999000999001" /xcortree=2597 /SigmaFactorBS="gcggacatgaatgttcacaggattgcttttgtatttattacc gtctaaatgcccagtTGTGGTAAAATAGAAAAGTTgaatcttcgtagaaaatggtgat g" /listShort="ytgP, ytzG" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(2940811) /Source="Nicolas_upshifts" /id="U2335" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.631368631368631" /psig="0.999000999001" /xcortree=2597 /SigmaFactorBS="gcggacatgaatgttcacaggattgcttttgtatttattacc gtctaaatgcccagtTGTGGTAAAATAGAAAAGTTgaatcttcgtagaaaatggtgat g" /listShort="ytgP, ytzG" /GFF_Attribute="listLong" promotor_-35 2940881..2940885 /Source="Nicolas_upshift_promotors" /id="U2336" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.725274725274725" /psig=1 /xcortree=2734 /SigmaFactorBS="cattcatgtccgcggcaaaagaCGTTTaaggagcggctttct TTCGCTATAATAGTACTGCGgacgggtgtccgcacacgaaatgaaaagaaagttgatg a" /listShort="ytfP, S1152, S1153, opuD" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2940901..2940920 /Source="Nicolas_upshift_promotors" /id="U2336" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.725274725274725" /psig=1 /xcortree=2734 /SigmaFactorBS="cattcatgtccgcggcaaaagaCGTTTaaggagcggctttct TTCGCTATAATAGTACTGCGgacgggtgtccgcacacgaaatgaaaagaaagttgatg a" /listShort="ytfP, S1152, S1153, opuD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2940919 /Source="Nicolas_upshifts" /id="U2336" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.725274725274725" /psig=1 /xcortree=2734 /SigmaFactorBS="cattcatgtccgcggcaaaagaCGTTTaaggagcggctttct TTCGCTATAATAGTACTGCGgacgggtgtccgcacacgaaatgaaaagaaagttgatg a" /listShort="ytfP, S1152, S1153, opuD" /GFF_Attribute="listLong" CDS 2940965..2942227 /gene="ytfP" /locus_tag="BSU_30060" /old_locus_tag="BSU30060" /EC_number="1.-.-.-" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative NAD(FAD)-utilizing dehydrogenase" /protein_id="NP_390884.2" /db_xref="EnsemblGenomes-Gn:BSU30060" /db_xref="EnsemblGenomes-Tr:CAB14984" /db_xref="InterPro:IPR004792" /db_xref="InterPro:IPR036188" /db_xref="SubtiList:BG13850" /db_xref="UniProtKB/Swiss-Prot:Q795R8" /translation="MKQYDVIVIGGGPSGLMAAIAAGEQGAGVLLIDKGNKLGRKLAI SGGGRCNVTNRLPVEEIIKHIPGNGRFLYSAFSEFNNEDIIKFFENLGIQLKEEDHGR MFPVTDKAQSVVDALLNRLKQLRVTIRTNEKIKSVLYEDGQAAGIVTNNGEMIHSQAV IIAVGGKSVPHTGSTGDGYEWAEAAGHTITELFPTEVPVTSGEPFIKQKTLQGLSLRD VAVSVLNKKGKPIITHKMDMLFTHFGLSGPAILRCSQFVVKELKKQPQVPIRIDLYPD INEETLFQKMYKELKEAPKKTIKNVLKPWMQERYLLFLLEKNGISPNVSFSELPKDPF RQFVRDCKQFTVLANGTLSLDKAFVTGGGVSVKEIDPKKMASKKMEGLYFCGEILDIH GYTGGYNITSALVTGRLAGLNAGQYARS*" gene 2940965..2942227 /gene="ytfP" /locus_tag="BSU_30060" /old_locus_tag="BSU30060" S_feature 2942228..2942326 /Source="Nicolas_S_feature" /locus_tag="new_3076630_3076728" /HighExp="LBGstat, Lbstat, M0t90, T2.30H, T1.0H, T0.30H, BC, T2.0H, T1.30H, Sw" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1152" promotor_-35 2942300..2942306 /Source="Nicolas_upshift_promotors" /id="U2337" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.996003996003996" /psig="0.996003996003996" /xcortree=147 /SigmaFactorBS="aacattccccgcattcatgttagggtgagactTGTTTTGttt cacctgattgcgGGGTAATTTTAAGAGAGGAatgagctgccatcgtacgaccatacta a" /listShort="S1153, opuD" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2942322..2942340 /Source="Nicolas_upshift_promotors" /id="U2337" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.996003996003996" /psig="0.996003996003996" /xcortree=147 /SigmaFactorBS="aacattccccgcattcatgttagggtgagactTGTTTTGttt cacctgattgcgGGGTAATTTTAAGAGAGGAatgagctgccatcgtacgaccatacta a" /listShort="S1153, opuD" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 2942328..2942415 /Source="Nicolas_S_feature" /locus_tag="new_3076730_3076817" /HighExp="Etha, LBGstat, Salt, M9-stat, Lbstat, LBGtran, Sw, C30, Gly, LoTm" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigB, SigA" /TUshortPSig="0.996, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S1153" upshifts 2942328 /Source="Nicolas_upshifts" /id="U2337" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.996003996003996" /psig="0.996003996003996" /xcortree=147 /SigmaFactorBS="aacattccccgcattcatgttagggtgagactTGTTTTGttt cacctgattgcgGGGTAATTTTAAGAGAGGAatgagctgccatcgtacgaccatacta a" /listShort="S1153, opuD" /GFF_Attribute="listLong" CDS 2942416..2943954 /gene="opuD" /locus_tag="BSU_30070" /old_locus_tag="BSU30070" /function="16.1: Circulate" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:14996799, 15849754, 16850406, 8752321, 9925583" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 14996799, 15849754, 16850406, 8752321, 9925583; Product type t: transporter" /codon_start=1 /transl_table=11 /product="glycine betaine transporter" /protein_id="NP_390885.1" /db_xref="EnsemblGenomes-Gn:BSU30070" /db_xref="EnsemblGenomes-Tr:CAB14985" /db_xref="GOA:P54417" /db_xref="InterPro:IPR000060" /db_xref="InterPro:IPR018093" /db_xref="SubtiList:BG11958" /db_xref="UniProtKB/Swiss-Prot:P54417" /translation="MLKHISSVFWIVIAITAAAVLWGVISPDSLQNVSQSAQAFITDS FGWYYLLVVSLFVGFCLFLIFSPIGKIKLGKPDEKPEFGLLSWFAMLFSAGMGIGLVF YGAAEPISHYAISSPSGETETPQAFRDALRYTFFHWGLHAWAIYAIVALCIAYFQFRK GAPGLISSTLSPILGDKVNGPIGKAIDCIAVFATVVGVSTSLGLGATQINGGLNYLFG IPNAFIVQLVLIIIVTVLFLLSAWSGLGKGIKYLSNTNMVLAGLLMLFMLVVGPTVLI MNSFTDSIGQYIQNIVQMSFRLTPNDPEKREWINSWTIFYWAWWISWSPFVGIFIARV SRGRTIREFLIGVLVTPCILTFLWFSIFGVSAMDLQQKGAFNVAKLSTETMLFGTLDH YPLTMVTSILALILIAVFFITSADSATFVLGMQTSYGSLNPANSVKLSWGIIQSAMAA VLLYSGGLAALQNTAILAALPFSIVILLMIASLYQSLSKERREIKKAEKLDKPRSPRV KKAY*" gene 2942416..2943954 /gene="opuD" /locus_tag="BSU_30070" /old_locus_tag="BSU30070" downshifts 2943934 /Source="Nicolas_upshifts" /id="D1552" /incds=0 /nref=231 /ntot=263 /MaxReadThrough="2.0688" /MaxDrop="6.06429" /score="27.1497809" /energy="-16.3" /TU="NA" /idTUdmin="U2336" /TUdmin=0 /isTUend="TRUE" CDS complement(2943991..2944173) /gene="yteV" /locus_tag="BSU_30080" /old_locus_tag="BSU30080" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 8990290" /codon_start=1 /transl_table=11 /product="conserved sporulation-related protein" /protein_id="NP_390886.1" /db_xref="EnsemblGenomes-Gn:BSU30080" /db_xref="EnsemblGenomes-Tr:CAB14986" /db_xref="GOA:P94496" /db_xref="InterPro:IPR020296" /db_xref="SubtiList:BG12339" /db_xref="UniProtKB/Swiss-Prot:P94496" /translation="MLKVAVFDEEHEKDLQTEINSFLKGISEEQLIDIKYTVSAACDP DGEQLYCFSALILYRK*" gene complement(2943991..2944173) /gene="yteV" /locus_tag="BSU_30080" /old_locus_tag="BSU30080" downshifts complement(2944010) /Source="Nicolas_upshifts" /id="D1553" /incds=0 /nref=10 /ntot=61 /MaxReadThrough="0.597819999999999" /MaxDrop="4.78152" /score="32.507978" /energy="-16.3" /TU="NA" /idTUdmin="U2338" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(2944188..2944206) /Source="Nicolas_upshift_promotors" /id="U2338" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=963 /SigmaFactorBS="gaaagctttttatccggaaacgagataatcatcatttctctA TCATAacgctgttccaaacgGAATAGATTGATAGAGAAAggagagcggataaaatgct g" /listShort="yteV" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2944208) /Source="Nicolas_upshifts" /id="U2338" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=963 /SigmaFactorBS="gaaagctttttatccggaaacgagataatcatcatttctctA TCATAacgctgttccaaacgGAATAGATTGATAGAGAAAggagagcggataaaatgct g" /listShort="yteV" /GFF_Attribute="listLong" promotor_-35 complement(2944222..2944227) /Source="Nicolas_upshift_promotors" /id="U2338" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=963 /SigmaFactorBS="gaaagctttttatccggaaacgagataatcatcatttctctA TCATAacgctgttccaaacgGAATAGATTGATAGAGAAAggagagcggataaaatgct g" /listShort="yteV" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2944241..2944909) /gene="rmgU" /locus_tag="BSU_30090" /old_locus_tag="BSU30090" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406, 17449691, 23504016; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative membrane enzyme for rhamnogalaturonan degradation" /protein_id="NP_390887.1" /db_xref="EnsemblGenomes-Gn:BSU30090" /db_xref="EnsemblGenomes-Tr:CAB14987" /db_xref="GOA:O34378" /db_xref="InterPro:IPR006938" /db_xref="SubtiList:BG13846" /db_xref="UniProtKB/Swiss-Prot:O34378" /translation="MEHDGSLGRMLRFCEWIMRFAYTNLLWLFFTLLGLGVFGIMPAT AALFAVMRKWIQGQDNVPVLKTFWQEYKGEFFRSNLLGAVLALIGVIIYIDLALIYPS HFLLHILRFAIMIFGFLFVSMLFYVFPLLVHFDWKKRLYVKFSLLLSVAYLQYTLTML ALTVALFFLLAYLPGIVPFFSVSLISYCHMRIVYAVLLKVEQHGGEPQRKSHIRKAFY PETR*" gene complement(2944241..2944909) /gene="rmgU" /locus_tag="BSU_30090" /old_locus_tag="BSU30090" CDS complement(2944931..2946217) /gene="rmgT" /locus_tag="BSU_30100" /old_locus_tag="BSU30100" /EC_number="1.1.-.-" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 17449691, 23504016; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative dehydrogenase of rhamnogalaturonan degradation" /protein_id="NP_390888.1" /db_xref="EnsemblGenomes-Gn:BSU30100" /db_xref="EnsemblGenomes-Tr:CAB14988" /db_xref="GOA:O34371" /db_xref="InterPro:IPR000683" /db_xref="InterPro:IPR004104" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG13845" /db_xref="UniProtKB/Swiss-Prot:O34371" /translation="MKNIVFCGLSSRAFSMFIKPLMERFSTHYEITGLLDADPKRFAV CKKKFPELAHVPEFSEDAFDEMMRVSKPDIVIVAGRDDTHVAYIVKSLQWNTDVITEK PMVTTVQDANRVLEAEAKSEGKVTVAFNYRYSPFHRKIKEMILDGKIGRVTSVDLNWY IDTYHGASYFKRWNRSRQFSGGLSVHKSTHHFDLVNWWLGQNPEEVFAYGALNYYGPD SEWNPLPEEDGRFCGTCRVKEKCHYYSRWHPRSSKASIKDDHLEAGDQSSLYTAYRPD ACIFDEEIDIEDTYVAAVKYDGGALLSYSIIFSAPYEGYRLTINGTKGRIESNEFHEP SRIPFAFPEQTIEYYPLFESKQTIQVVKNEGGHGGGDPLLLEDLFLGKDPLRRYDILA GAEAGAYSIAVGEGMWRSVAEKKPIGMKELFQMQNV*" gene complement(2944931..2946217) /gene="rmgT" /locus_tag="BSU_30100" /old_locus_tag="BSU30100" CDS complement(2946229..2946732) /gene="rmgS" /locus_tag="BSU_30110" /old_locus_tag="BSU30110" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:17449691, 23504016" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 17449691, 23504016; Product type lp: lipoprotein" /codon_start=1 /transl_table=11 /product="lipoprotein required for rhamnogalaturonan transport and degradation" /protein_id="NP_390889.2" /db_xref="EnsemblGenomes-Gn:BSU30110" /db_xref="EnsemblGenomes-Tr:CAB14989" /db_xref="GOA:C0SP80" /db_xref="SubtiList:BG13844" /db_xref="UniProtKB/Swiss-Prot:C0SP80" /translation="MTKRIRTALCVIVSVLFLASCSSRPDGMHVILFSDMQAGVQEKI KKAAEQNAGKVDIFPAFQEKLLTEITAHEGDVFIVPEDMFQAYDDPENFQPLNGLPPE KTSPYTTVNKKTGEKTIYAVQIEKGKKQLNGYSFQLNRDMAAFIPVYAEKTEEALQLI SQLTEAR*" gene complement(2946229..2946732) /gene="rmgS" /locus_tag="BSU_30110" /old_locus_tag="BSU30110" CDS complement(2946729..2947850) /gene="rmgQ" /locus_tag="BSU_30120" /old_locus_tag="BSU30120" /EC_number="3.2.1.172" /function="16.8: Protect" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:15148314, 15906318, 16781735, 16870154, 17449691, 23504016" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15148314, 15906318, 16781735, 16870154, 17449691, 23504016; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="unsaturated rhamnogalacturonyl hydrolase" /protein_id="NP_390890.3" /db_xref="EnsemblGenomes-Gn:BSU30120" /db_xref="EnsemblGenomes-Tr:CAB14990" /db_xref="GOA:O34559" /db_xref="InterPro:IPR008928" /db_xref="InterPro:IPR010905" /db_xref="PDB:1NC5" /db_xref="PDB:2D8L" /db_xref="PDB:2GH4" /db_xref="SubtiList:BG13843" /db_xref="UniProtKB/Swiss-Prot:O34559" /translation="MGSMDQSIAVKSPLTYAEALANTIMNTYTVEELPPANRWHYHQG VFLCGVLRLWEATGEKRYFEYAKAYADLLIDDNGNLLFRRDELDAIQAGLILFPLYEQ TKDERYVKAAKRLRSLYGTLNRTSEGGFWHKDGYPYQMWLDGLYMGGPFALKYANLKQ ETELFDQVVLQESLMRKHTKDAKTGLFYHAWDEAKKMPWANEETGCSPEFWARSIGWY VMSLADMIEELPKKHPNRHVWKNTLQDMIKSICRYQDKETGLWYQIVDKGDRSDNWLE SSGSCLYMYAIAKGINKGYLDRAYETTLLKAYQGLIQHKTETSEDGAFLVKDICVGTS AGFYDYYVSRERSTNDLHGAGAFILAMTELEPLFRSAGK*" gene complement(2946729..2947850) /gene="rmgQ" /locus_tag="BSU_30120" /old_locus_tag="BSU30120" CDS complement(2947858..2948823) /gene="rmgP" /locus_tag="BSU_30135" /old_locus_tag="BSU30135" /experiment="publication(s) with functional evidences, PMID:15849754, 16850406, 17449691, 23504016" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15849754, 16850406, 17449691, 23504016; Product type t: transporter" /codon_start=1 /transl_table=11 /product="permease for unsaturated rhamnogalacturonan" /protein_id="NP_390892.2" /db_xref="EnsemblGenomes-Gn:BSU30135" /db_xref="EnsemblGenomes-Tr:CAB14992" /db_xref="GOA:C0SPB3" /db_xref="InterPro:IPR000515" /db_xref="InterPro:IPR035906" /db_xref="SubtiList:BG13841" /db_xref="UniProtKB/Swiss-Prot:C0SPB3" /translation="MKTAEAQAPAVDAVIFKKEKRKRLLIKLIQQKYLYLMILPGCIY FLLFKYVPMWGIVIAFQDYQPFLGILGSEWVGLKHFIRLFTEPTFFLLLKNTLVLFAL NLAIFFPVPILLALLLNEVRIALFKKFVQTLIYIPHFMSWVIVVSLSFVLLTVDGGLI NELIVFFGGEKINFLLNEEWFRPLYILQVIWREAGWSTIIYLAAITAVDPQLYEAAKM DGAGRLRQMWHITLPAIKSVIVVLLILKIGDTLELGFEHVYLLLNATNREVAEIFDTY VYTAGLKQGQFSYSTAVGVFKAAVGLILVMLANRLAKKFGEEGIY*" gene complement(2947858..2948823) /gene="rmgP" /locus_tag="BSU_30135" /old_locus_tag="BSU30135" upshifts complement(2948849) /Source="Nicolas_upshifts" /id="U2339" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.75924075924076" /psig="0.918081918081918" /xcortree=341 /SigmaFactorBS="caggatgtgatcatatgaTTGTAGACggacttttgcctgcTG CGCTACAGTGAATGCAAGaatccgtgaaaggaggctaggaaaaaatgaaaacagcaga a" /listShort="yteP" /GFF_Attribute="listLong" promotor_-10 complement(2948850..2948869) /Source="Nicolas_upshift_promotors" /id="U2339" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.75924075924076" /psig="0.918081918081918" /xcortree=341 /SigmaFactorBS="caggatgtgatcatatgaTTGTAGACggacttttgcctgcTG CGCTACAGTGAATGCAAGaatccgtgaaaggaggctaggaaaaaatgaaaacagcaga a" /listShort="yteP" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 complement(2948884..2948891) /Source="Nicolas_upshift_promotors" /id="U2339" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.75924075924076" /psig="0.918081918081918" /xcortree=341 /SigmaFactorBS="caggatgtgatcatatgaTTGTAGACggacttttgcctgcTG CGCTACAGTGAATGCAAGaatccgtgaaaggaggctaggaaaaaatgaaaacagcaga a" /listShort="yteP" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 2948979..2948986 /Source="Nicolas_upshift_promotors" /id="U2340" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.965034965034965" /psig="0.998001998001998" /xcortree=561 /SigmaFactorBS="cggtccacctgaaaaaaagacaccgatattagaaaatgatTA TTGACAatatctatcaatcttTGGATTAATTGTATTAAGGTgaagtggatgttatgaa a" /listShort="ytdP" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 2948999 /Source="Nicolas_upshifts" /id="U2340" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.965034965034965" /psig="0.998001998001998" /xcortree=561 /SigmaFactorBS="cggtccacctgaaaaaaagacaccgatattagaaaatgatTA TTGACAatatctatcaatcttTGGATTAATTGTATTAAGGTgaagtggatgttatgaa a" /listShort="ytdP" /GFF_Attribute="listLong" promotor_-10 2949002..2949021 /Source="Nicolas_upshift_promotors" /id="U2340" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.965034965034965" /psig="0.998001998001998" /xcortree=561 /SigmaFactorBS="cggtccacctgaaaaaaagacaccgatattagaaaatgatTA TTGACAatatctatcaatcttTGGATTAATTGTATTAAGGTgaagtggatgttatgaa a" /listShort="ytdP" /GFF_Attribute="listLong" /label="promotor_-10" CDS 2949039..2951357 /gene="rmgR" /locus_tag="BSU_30150" /old_locus_tag="BSU30150" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2b: Function from indirect experimental evidences (e.g. phenotypes); PubMedId: 23504016; Product type r: regulator" /codon_start=1 /transl_table=11 /product="membrane bound transcriptional regulator (controlling rhamnogalacturonan degradation)" /protein_id="NP_390893.1" /db_xref="EnsemblGenomes-Gn:BSU30150" /db_xref="EnsemblGenomes-Tr:CAB14993" /db_xref="GOA:O32071" /db_xref="InterPro:IPR009057" /db_xref="InterPro:IPR018060" /db_xref="SubtiList:BG13838" /db_xref="UniProtKB/Swiss-Prot:O32071" /translation="MGGFMKRSQYKFYYKLITFFCLLSTIPVILVGLFSYEHSQKTAI SNVSEEKFDTLQQTQQSIEHILKTVDHSLTHYVSSPPLLRTLSEPLHSDQFQIYNQVN QELNYLQSFDTDLSNMTLVSYTKKWYMNNSGLYRLNTDTLHEAASAYTKQKASRSYWT LEENNHLISTKEGTAENCRYNINLIKQLPLNSTNTKGLAAASIPSCSLVKNMPGYSNA NNLFIIDEKGLIILHNNMSDVGESLHNDGFVQKVLAQTANSGQFETVIDRIHYKVTYQ KSDYNAWTYFSLVSLPELKKEAKSIGWITFAVCLILLTLSLLFSWLGSRHFYKPIRVL YESFARHGAIQEKQQPPQNEFELIEQSFKQLKDRNDDLEETMKQQATHLQQYFMVRLM LGKLTDEEVDNRFESLGLKQNWRHLALLVLQIDTLNHTPYEKKDMDLLLFAVNSLIER NIPTDKHLAPAVVDKQQATILINQSGTKEEFMAELNETARMIQEKAEAELQLSVSIGI SQPFDVLTKAKTAYAEGSEALKYRLKAENKSIIFYEDLDQKKTFKTHFPKQLQHELFD AVKAGDKEKADKCLHAILQAIFTQNTNPYQFQIAIARFLNHVIELMHVLGIELFELEE NKMLYDQIFELKTFEDTENWLKNEFIDPMTDKVNARADAQYKNISDNIIHIIHHEFES ELTLDEIARRLHYNPNYLSSIFKKEMGISFSEYVSSYRHHMAKSWLAETDMAVKDIAE KLKYKNSQNFIRSFKKLEGITPGNYRQQKRSM*" gene 2949039..2951357 /gene="rmgR" /locus_tag="BSU_30150" /old_locus_tag="BSU30150" downshifts 2951347 /Source="Nicolas_upshifts" /id="D1554" /incds=0 /nref=8 /ntot=42 /MaxReadThrough="1.43431" /MaxDrop="3.6268" /score="-7.37324741" /energy="-10.2" /TU="NA" /idTUdmin="U2340" /TUdmin=1870 /isTUend="FALSE" CDS complement(2951398..2952894) /gene="ytcQ" /locus_tag="BSU_30160" /old_locus_tag="BSU30160" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type lp: lipoprotein" /codon_start=1 /transl_table=11 /product="putative ABC transporter (binding lipoprotein)" /protein_id="NP_390894.3" /db_xref="EnsemblGenomes-Gn:BSU30160" /db_xref="EnsemblGenomes-Tr:CAB14994" /db_xref="GOA:Q795R2" /db_xref="SubtiList:BG13836" /db_xref="UniProtKB/Swiss-Prot:Q795R2" /translation="MGNKWRVLLIVLVLALGGVLAGCKGTDQSSAEGKAGPDSKVKLS WMAILYHQQPPKDRAIKEIEKLTNTELDITWVPDAVKEDRLNAALAAGNLPQIVTIQD IKNSSVMNAFRSGMFWEIGDYIKDYPNLNKMNKLINKNVTIDGKLYGIYRERPLSRQG IVIRKDWLDNLNLKTPKTLDELYEVAKAFTEDDPDKDGKDDTFGLADRNDLIYGAFKT IGSYEGMPTDWKESGGKFTPDFMTQEYKDTMNYMKKLRDNGYMNKDFPVTSKTQQQEL FSQGKAGIYIGNMVDAVNLRDHASDKSMKLEIINRIKGPDGKERVWASGGHNGVFAFP KTSVKTEAELKRILAFFDRIAEEDVYSLMTYGIDGVHYNKGEDKTFTRKESQVKDWQT DIQPLSALIAIDKAYLKNTGDPLRTAYEELTEDNEKIIVSNPAESLYSASESERGDEL KKIIDDATYKYMIGDITESQFDKEVEKWESSGGKQIIQEYEEAFKQAK*" gene complement(2951398..2952894) /gene="ytcQ" /locus_tag="BSU_30160" /old_locus_tag="BSU30160" downshifts complement(2951400) /Source="Nicolas_upshifts" /id="D1555" /incds=0 /nref=26 /ntot=160 /MaxReadThrough="-0.0485899999999999" /MaxDrop="5.21039" /score="6.31011081" /energy="-11.2" /TU="NA" /idTUdmin="U2341" /TUdmin=1 /isTUend="TRUE" CDS complement(2952919..2953779) /gene="ytcP" /locus_tag="BSU_30170" /old_locus_tag="BSU30170" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative ABC transporter (permease)" /protein_id="NP_390895.1" /db_xref="EnsemblGenomes-Gn:BSU30170" /db_xref="EnsemblGenomes-Tr:CAB14995" /db_xref="GOA:P53561" /db_xref="InterPro:IPR000515" /db_xref="InterPro:IPR035906" /db_xref="SubtiList:BG11788" /db_xref="UniProtKB/Swiss-Prot:P53561" /translation="MKNRLFDMLIYGFLLMFALICVLPFIHVIAASFATVEEVVSKKF ILIPTTFSLDAYRYIFSTDIIYKSLLVSVFVTVIGTAVSMFLSSLMAYGLSRRDLIGR QPLMFLVVFTMLFSGGMIPTFLVVKSLGLLDSYWALILPTAINAFNLIILKNFFQNIP SSLEESAKIDGCNDLGIFFKIVLPLSLPAIATISLFYAVTYWNTYMTAILYLNDSAKW PIQVLLRQIVIVSSGMQGDMSEMGSGSPPPEQTIKMAVIVVATIPVLLVYPFIQKHFA KGALLGSVKG*" gene complement(2952919..2953779) /gene="ytcP" /locus_tag="BSU_30170" /old_locus_tag="BSU30170" promotor_-10 complement(2953855..2953874) /Source="Nicolas_upshift_promotors" /id="U2341" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.72927072927073" /psig="0.998001998001998" /xcortree=353 /SigmaFactorBS="cccggccggggacactgttcaaatgatTATAGACAtggcaat cacagattTGCTACATTTTAGACACGATatcgtcacatgctgagctcggtttccaaaa a" /listShort="ytcP, ytcQ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2953864) /Source="Nicolas_upshifts" /id="U2341" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.72927072927073" /psig="0.998001998001998" /xcortree=353 /SigmaFactorBS="cccggccggggacactgttcaaatgatTATAGACAtggcaat cacagattTGCTACATTTTAGACACGATatcgtcacatgctgagctcggtttccaaaa a" /listShort="ytcP, ytcQ" /GFF_Attribute="listLong" promotor_-35 complement(2953890..2953897) /Source="Nicolas_upshift_promotors" /id="U2341" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.72927072927073" /psig="0.998001998001998" /xcortree=353 /SigmaFactorBS="cccggccggggacactgttcaaatgatTATAGACAtggcaat cacagattTGCTACATTTTAGACACGATatcgtcacatgctgagctcggtttccaaaa a" /listShort="ytcP, ytcQ" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2953986..2954747) /gene="ytbQ" /locus_tag="BSU_30180" /old_locus_tag="BSU30180" /function="16.8: Protect" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative NAD-dependent nucleoside-diphosphate-sugar epimerase" /protein_id="NP_390896.2" /db_xref="EnsemblGenomes-Gn:BSU30180" /db_xref="EnsemblGenomes-Tr:CAB14996" /db_xref="GOA:P53560" /db_xref="InterPro:IPR001509" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG11787" /db_xref="UniProtKB/Swiss-Prot:P53560" /translation="MKKVLIAGGNGVIGRLLAEGLISDYEVTVLDKDHFDGKASSIQA DAANYEELLKKIPKDTDAILNLLAVKIKYDIMDIAEFEKMTDVFYRASYYLCRAAAEL GIQKLVFASSNHVTDVYEKDGRSLLGREITTSDYPLSKNLYGVLKLTSEQIGHLFYLE NKLSVINLRIGTVVTDEMDTLHEKERTKKTLLSHPDLLSIFKAAIETNIRYGTYYAVS DNPGRPWSIESAVNELGFSPQINTAELLNEEENGA*" gene complement(2953986..2954747) /gene="ytbQ" /locus_tag="BSU_30180" /old_locus_tag="BSU30180" downshifts complement(2954015) /Source="Nicolas_upshifts" /id="D1556" /incds=0 /nref=153 /ntot=196 /MaxReadThrough="1.18543" /MaxDrop="5.85654" /score="12.3836957" /energy="-11.1" /TU="NA" /idTUdmin="U2344" /TUdmin="-19" /isTUend="TRUE" S_feature complement(2954748..2954823) /Source="Nicolas_S_feature" /locus_tag="new_3089150_3089225_c" /HighExp="LPh, HPh, aero, Gly, HiOs, BMM, GM-0.1, GM 10, GM 15, HiTm" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1154" CDS complement(2954824..2956011) /gene="bioI" /locus_tag="BSU_30190" /old_locus_tag="BSU30190" /EC_number="1.14.14.46" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:11368323, 11472016, 12943422, 20658980, 21435937, 21437340, 28196402" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11368323, 11472016, 12943422, 20658980, 21435937, 21437340, 28196402; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="cytochrome P450 for pimelic acid formation for biotin biosynthesis" /protein_id="NP_390897.1" /db_xref="EnsemblGenomes-Gn:BSU30190" /db_xref="EnsemblGenomes-Tr:CAB14997" /db_xref="GOA:P53554" /db_xref="InterPro:IPR001128" /db_xref="InterPro:IPR002397" /db_xref="InterPro:IPR017972" /db_xref="InterPro:IPR036396" /db_xref="PDB:3EJB" /db_xref="PDB:3EJD" /db_xref="PDB:3EJE" /db_xref="SubtiList:BG11528" /db_xref="UniProtKB/Swiss-Prot:P53554" /translation="MTIASSTASSEFLKNPYSFYDTLRAVHPIYKGSFLKYPGWYVTG YEETAAILKDARFKVRTPLPESSTKYQDLSHVQNQMMLFQNQPDHRRLRTLASGAFTP RTTESYQPYIIETVHHLLDQVQGKKKMEVISDFAFPLASFVIANIIGVPEEDREQLKE WAASLIQTIDFTRSRKALTEGNIMAVQAMAYFKELIQKRKRHPQQDMISMLLKGREKD KLTEEEAASTCILLAIAGHETTVNLISNSVLCLLQHPEQLLKLRENPDLIGTAVEECL RYESPTQMTARVASEDIDICGVTIRQGEQVYLLLGAANRDPSIFTNPDVFDITRSPNP HLSFGHGHHVCLGSSLARLEAQIAINTLLQRMPSLNLADFEWRYRPLFGFRALEELPV TFE*" gene complement(2954824..2956011) /gene="bioI" /locus_tag="BSU_30190" /old_locus_tag="BSU30190" CDS complement(2956080..2957087) /gene="bioB" /locus_tag="BSU_30200" /old_locus_tag="BSU30200" /EC_number="2.8.1.6" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:2110099, 8763940, 11717296, 12368242" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 2110099, 8763940, 11717296, 12368242; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="biotin synthase" /protein_id="NP_390898.1" /db_xref="EnsemblGenomes-Gn:BSU30200" /db_xref="EnsemblGenomes-Tr:CAB14998" /db_xref="GOA:P53557" /db_xref="InterPro:IPR002684" /db_xref="InterPro:IPR006638" /db_xref="InterPro:IPR007197" /db_xref="InterPro:IPR010722" /db_xref="InterPro:IPR013785" /db_xref="InterPro:IPR024177" /db_xref="SubtiList:BG11525" /db_xref="UniProtKB/Swiss-Prot:P53557" /translation="MNQWMELADRVLAGAEVTDEEALSILHCPDEDILLLMHGAFHIR KHFYGKKVKLNMIMNAKSGLCPENCGYCSQSAISKAPIESYRMVNKETLLEGAKRAHD LNIGTYCIVASGRGPSNREVDQVVDAVQEIKETYGLKICACLGLLKPEQAKRLKDAGV DRYNHNLNTSQRNHSNITTSHTYDDRVNTVEIAKESGLSPCSGAIIGMKETKQDVIDI AKSLKALDADSIPVNFLHAIDGTPLEGVNELNPLYCLKVLALFRFINPSKEIRISGGR EVNLRTLQPLGLYAANSIFVGDYLTTAGQEETEDHKMLSDLGFEVESVEEMKASLSAK S*" gene complement(2956080..2957087) /gene="bioB" /locus_tag="BSU_30200" /old_locus_tag="BSU30200" CDS complement(2957090..2957785) /gene="bioD" /locus_tag="BSU_30210" /old_locus_tag="BSU30210" /EC_number="6.3.3.3" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:2110099, 8763940, 11717296, 12368242, 20565114" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 2110099, 8763940, 11717296, 12368242, 20565114; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="dethiobiotin synthetase" /protein_id="NP_390899.1" /db_xref="EnsemblGenomes-Gn:BSU30210" /db_xref="EnsemblGenomes-Tr:CAB14999" /db_xref="GOA:P53558" /db_xref="InterPro:IPR004472" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG11526" /db_xref="UniProtKB/Swiss-Prot:P53558" /translation="MRGFFVTGTDTEVGKTVISSGLAALLKDNNRHVGVYKPFLSGIS RHHPDSDTSLLKDMSQTSLSHEDITPFAFKAPLAPYVAGKLEGKTVTMEEVLSHWGRI REKHECFIVEGAGGISVPLGEDYLVSHVIKALQLPMIIVARPRLGTINHTFLTVKYAE SMGLPIAGIIINGISDSPDEDEKTNPEMIERLCGVPILGVTPKLANVTKETVLHMVKD HINLSLLMNQVGV*" gene complement(2957090..2957785) /gene="bioD" /locus_tag="BSU_30210" /old_locus_tag="BSU30210" CDS complement(2957782..2958951) /gene="bioFC" /locus_tag="BSU_30220" /old_locus_tag="BSU30220" /EC_number="2.3.1.-" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:8763940, 11322938, 11717296, 12368242, 15056910, 16557306" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8763940, 11322938, 11717296, 12368242, 15056910, 16557306; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="8-amino-7-oxononanoate synthase (pimeloyl-CoA-dependent)" /protein_id="NP_390900.1" /db_xref="EnsemblGenomes-Gn:BSU30220" /db_xref="EnsemblGenomes-Tr:CAB15000" /db_xref="GOA:P53556" /db_xref="InterPro:IPR001917" /db_xref="InterPro:IPR004723" /db_xref="InterPro:IPR004839" /db_xref="InterPro:IPR015421" /db_xref="InterPro:IPR015422" /db_xref="InterPro:IPR015424" /db_xref="SubtiList:BG11527" /db_xref="UniProtKB/Swiss-Prot:P53556" /translation="MKIDSWLNERLDRMKEAGVHRNLRSMDGAPVPERNIDGENQTVW SSNNYLGLASDRRLIDAAQTALQQFGTGSSGSRLTTGNSVWHEKLEKKIASFKLTEAA LLFSSGYLANVGVLSSLPEKEDVILSDQLNHASMIDGCRLSKADTVVYRHIDMNDLEN KLNETQRYQRRFIVTDGVFSMDGTIAPLDQIISLAKRYHAFVVVDDAHATGVLGDSGQ GTSEYFGVCPDIVIGTLSKAVGAEGGFAAGSAVFIDFLLNHARTFIFQTAIPPASCAA AHEAFNIIEASREKRQLLFSYISMIRTSLKNMGYVVKGDHTPIIPVVIGDAHKTVLFA EKLQGKGIYAPAIRPPTVAPGESRIRITITSDHSMGDIDHLLQTFHSIGKELHII*" gene complement(2957782..2958951) /gene="bioFC" /locus_tag="BSU_30220" /old_locus_tag="BSU30220" promotor_-35 2957818..2957825 /Source="Nicolas_upshift_promotors" /id="U2342" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.996003996003996" /psig="0.997002997002997" /xcortree=2064 /SigmaFactorBS="tcctttccgattgaatgaaaTGTTTGCAgcaaatgatcaata TCACCCATACTGTGGTCAGAcgtgattgtaattcgaatccggctttcacccggcgcaa c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2957840..2957859 /Source="Nicolas_upshift_promotors" /id="U2342" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.996003996003996" /psig="0.997002997002997" /xcortree=2064 /SigmaFactorBS="tcctttccgattgaatgaaaTGTTTGCAgcaaatgatcaata TCACCCATACTGTGGTCAGAcgtgattgtaattcgaatccggctttcacccggcgcaa c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2957858 /Source="Nicolas_upshifts" /id="U2342" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.996003996003996" /psig="0.997002997002997" /xcortree=2064 /SigmaFactorBS="tcctttccgattgaatgaaaTGTTTGCAgcaaatgatcaata TCACCCATACTGTGGTCAGAcgtgattgtaattcgaatccggctttcacccggcgcaa c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" CDS complement(2958941..2960287) /gene="bioK" /locus_tag="BSU_30230" /old_locus_tag="BSU30230" /EC_number="2.6.1.105" /function="4.1: Biotin" /experiment="publication(s) with functional evidences, PMID:15880481, 20565114, 21437340" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15880481, 20565114, 21437340; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="L-lysine-8-amino-7-oxononanoate aminotransferase" /protein_id="NP_390901.1" /db_xref="EnsemblGenomes-Gn:BSU30230" /db_xref="EnsemblGenomes-Tr:CAB15001" /db_xref="GOA:P53555" /db_xref="InterPro:IPR005814" /db_xref="InterPro:IPR005815" /db_xref="InterPro:IPR015421" /db_xref="InterPro:IPR015422" /db_xref="InterPro:IPR015424" /db_xref="PDB:3DOD" /db_xref="PDB:3DRD" /db_xref="PDB:3DU4" /db_xref="SubtiList:BG11524" /db_xref="UniProtKB/Swiss-Prot:P53555" /translation="MTHDLIEKSKKHLWLPFTQMKDYDENPLIIESGTGIKVKDINGK EYYDGFSSVWLNVHGHRKKELDDAIKKQLGKIAHSTLLGMTNVPATQLAETLIDISPK KLTRVFYSDSGAEAMEIALKMAFQYWKNIGKPEKQKFIAMKNGYHGDTIGAVSVGSIE LFHHVYGPLMFESYKAPIPYVYRSESGDPDECRDQCLRELAQLLEEHHEEIAALSIES MVQGASGMIVMPEGYLAGVRELCTTYDVLMIVDEVATGFGRTGKMFACEHENVQPDLM AAGKGITGGYLPIAVTFATEDIYKAFYDDYENLKTFFHGHSYTGNQLGCAVALENLAL FESENIVEQVAEKSKKLHFLLQDLHALPHVGDIRQLGFMCGAELVRSKETKEPYPADR RIGYKVSLKMRELGMLTRPLGDVIAFLPPLASTAEELSEMVAIMKQAIHEVTSLED*" gene complement(2958941..2960287) /gene="bioK" /locus_tag="BSU_30230" /old_locus_tag="BSU30230" promotor_-35 2959357..2959361 /Source="Nicolas_upshift_promotors" /id="U2343" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.977022977022977" /psig="0.977022977022977" /xcortree=1183 /SigmaFactorBS="gccaagctgattgcctgtataggaatggccatggaaaaaggT TTTTaggttttcataatcaTCATAGAATGCCTTATAGAtgtcttcagtggcaaacgta a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 2959376 /Source="Nicolas_upshifts" /id="U2343" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.977022977022977" /psig="0.977022977022977" /xcortree=1183 /SigmaFactorBS="gccaagctgattgcctgtataggaatggccatggaaaaaggT TTTTaggttttcataatcaTCATAGAATGCCTTATAGAtgtcttcagtggcaaacgta a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 2959377..2959395 /Source="Nicolas_upshift_promotors" /id="U2343" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.977022977022977" /psig="0.977022977022977" /xcortree=1183 /SigmaFactorBS="gccaagctgattgcctgtataggaatggccatggaaaaaggT TTTTaggttttcataatcaTCATAGAATGCCTTATAGAtgtcttcagtggcaaacgta a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" CDS complement(2960277..2961053) /gene="bioW" /locus_tag="BSU_30240" /old_locus_tag="BSU30240" /EC_number="6.2.1.14" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:8763940, 11368323, 11717296, 21437340, 28196402, 29054876" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8763940, 11368323, 11717296, 21437340, 28196402, 29054876; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="6-carboxyhexanoate-CoA ligase (pimeloyl-CoA synthase)" /protein_id="NP_390902.3" /db_xref="EnsemblGenomes-Gn:BSU30240" /db_xref="EnsemblGenomes-Tr:CAB15002" /db_xref="GOA:P53559" /db_xref="InterPro:IPR005499" /db_xref="PDB:5FLG" /db_xref="PDB:5FLL" /db_xref="PDB:5FM0" /db_xref="PDB:5G1F" /db_xref="SubtiList:BG11529" /db_xref="UniProtKB/Swiss-Prot:P53559" /translation="MQEETFYSVRMRASMNGSHEDGGKHISGGERLIPFHEMKHTVNA LLEKGLSHSRGKPDFMQIQFEEVHESIKTIQPLPVHTNEVSCPEEGQKLARLLLEKEG VSRDVIEKAYEQIPEWSDVRGAVLFDIHTGKRMDQTKEKGVRVSRMDWPDANFEKWAL HSHVPAHSRIKEALALASKVSRHPAVVAELCWSDDPDYITGYVAGKKMGYQRITAMKE YGTEEGCRVFFIDGSNDVNTYIHDLEKQPILIEWEEDHDS*" gene complement(2960277..2961053) /gene="bioW" /locus_tag="BSU_30240" /old_locus_tag="BSU30240" S_feature complement(2961054..2961146) /Source="Nicolas_S_feature" /locus_tag="new_3095456_3095548_c" /HighExp="T-5.40H, GM 60, LPh, GM 25, HPh, MG 120, M9-exp, BMM, GM 5, MG 150" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1155" promotor_-10 complement(2961132..2961151) /Source="Nicolas_upshift_promotors" /id="U2344" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.998001998001998" /psig=1 /xcortree=2918 /SigmaFactorBS="tttaaccaactgccataaatcgatcctttcttcTATTGACAg aaacaggagagaaTAATATATTCTAATTGTTAAcctttgaatataattggttaacaat t" /listShort="S1155, bioW, bioK, bioF, bioD, bioB, bioI, S1154, ytbQ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2961146) /Source="Nicolas_upshifts" /id="U2344" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.998001998001998" /psig=1 /xcortree=2918 /SigmaFactorBS="tttaaccaactgccataaatcgatcctttcttcTATTGACAg aaacaggagagaaTAATATATTCTAATTGTTAAcctttgaatataattggttaacaat t" /listShort="S1155, bioW, bioK, bioF, bioD, bioB, bioI, S1154, ytbQ" /GFF_Attribute="listLong" promotor_-35 complement(2961166..2961173) /Source="Nicolas_upshift_promotors" /id="U2344" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.998001998001998" /psig=1 /xcortree=2918 /SigmaFactorBS="tttaaccaactgccataaatcgatcctttcttcTATTGACAg aaacaggagagaaTAATATATTCTAATTGTTAAcctttgaatataattggttaacaat t" /listShort="S1155, bioW, bioK, bioF, bioD, bioB, bioI, S1154, ytbQ" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2961263..2962162) /gene="ytaP" /locus_tag="BSU_30250" /old_locus_tag="BSU30250" /EC_number="3.-.-.-" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative hydrolase" /protein_id="NP_390903.1" /db_xref="EnsemblGenomes-Gn:BSU30250" /db_xref="EnsemblGenomes-Tr:CAB15003" /db_xref="GOA:O34973" /db_xref="InterPro:IPR002471" /db_xref="InterPro:IPR002925" /db_xref="InterPro:IPR029058" /db_xref="SubtiList:BG11786" /db_xref="UniProtKB/Swiss-Prot:O34973" /translation="MRAERRKQLFRLLGDLPDRRPISVETLRIEEREENIVETLLLDL NGHEKAPAYFVKPKKTEGPCPAVLFQHSHGGQYDRGKSELIEGADYLKTPSFSDELTS LGYGVLAIDHWGFGDRRGKAESEIFKEMLLTGKVMWGMMIYDSLSALDYMQSRSDVQP DRIGTIGMSMGGLMAWWTAALDDRIKVCVDLCSQVDHHVLIKTQNLDRHGFYYYVPSL AKHFSASEIQSLIAPRPHLSLVGVHDRLTPAEGVDKIEKELTAVYAGQGAADCYRVVR SASGHFETAVIRHEAVRFLQKWL*" gene complement(2961263..2962162) /gene="ytaP" /locus_tag="BSU_30250" /old_locus_tag="BSU30250" promotor_-10 complement(2962185..2962203) /Source="Nicolas_upshift_promotors" /id="U2345" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.994005994005994" /psig="0.994005994005994" /xcortree=517 /SigmaFactorBS="ctaaatatttagtaaatgatgtgatttatgttggaaaaatAA AGGGGAAcccagatctgTCTCGTAAATGTGAAGTAAgcgaataaggaagggtgatggg a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2962202) /Source="Nicolas_upshifts" /id="U2345" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.994005994005994" /psig="0.994005994005994" /xcortree=517 /SigmaFactorBS="ctaaatatttagtaaatgatgtgatttatgttggaaaaatAA AGGGGAAcccagatctgTCTCGTAAATGTGAAGTAAgcgaataaggaagggtgatggg a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(2962214..2962222) /Source="Nicolas_upshift_promotors" /id="U2345" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.994005994005994" /psig="0.994005994005994" /xcortree=517 /SigmaFactorBS="ctaaatatttagtaaatgatgtgatttatgttggaaaaatAA AGGGGAAcccagatctgTCTCGTAAATGTGAAGTAAgcgaataaggaagggtgatggg a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 2962292..2962299 /Source="Nicolas_upshift_promotors" /id="U2346" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.954045954045954" /psig="0.999000999001" /xcortree=330 /SigmaFactorBS="agtaaatattatggaatatttcgaaaacaatTATTGTAAccg cttacttttataTGATAATATCAATTTATCAAaaacagatgagttaatattttactaa a" /listShort="msmR, msmE, amyD, amyC, melA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2962315..2962334 /Source="Nicolas_upshift_promotors" /id="U2346" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.954045954045954" /psig="0.999000999001" /xcortree=330 /SigmaFactorBS="agtaaatattatggaatatttcgaaaacaatTATTGTAAccg cttacttttataTGATAATATCAATTTATCAAaaacagatgagttaatattttactaa a" /listShort="msmR, msmE, amyD, amyC, melA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2962321 /Source="Nicolas_upshifts" /id="U2346" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.954045954045954" /psig="0.999000999001" /xcortree=330 /SigmaFactorBS="agtaaatattatggaatatttcgaaaacaatTATTGTAAccg cttacttttataTGATAATATCAATTTATCAAaaacagatgagttaatattttactaa a" /listShort="msmR, msmE, amyD, amyC, melA" /GFF_Attribute="listLong" CDS 2962380..2963414 /gene="msmR" /locus_tag="BSU_30260" /old_locus_tag="BSU30260" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 12847288; Product type r : regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator (LacI family)" /protein_id="NP_390904.1" /db_xref="EnsemblGenomes-Gn:BSU30260" /db_xref="EnsemblGenomes-Tr:CAB15004" /db_xref="GOA:O34829" /db_xref="InterPro:IPR000843" /db_xref="InterPro:IPR010982" /db_xref="InterPro:IPR028082" /db_xref="SubtiList:BG12626" /db_xref="UniProtKB/Swiss-Prot:O34829" /translation="MVRIKDIALKAKVSSATVSRILNEDESLSVAGETRQRVINIAEE LGYQTVAKRRKSRGQKQRAQPLIGVLSCLSPDQERQDPYFSSIRKGIEKECFEQEIFI TNSIHLGSFQEHIFRELDGVIVIGRVHDEAVKHISGRLEHAVFINHSPDPQAYDSIGI DFESASRQAIDHLFDLGYKRLGYIGGQEKEHTLKDGQSIRRTIEDKRLTAFLESAAPQ PEHVLIGEYSMREGYRLMKKAIDQGHLPEAFFIASDSMAIGALKALQEAGLQVPRDTA IVSFNGIEEAEFASTPLTTVKVYTEEMGRTGVKLLLDRLNGRTLPQHVTLPTTLIVRQ SCGCTAKEVT*" gene 2962380..2963414 /gene="msmR" /locus_tag="BSU_30260" /old_locus_tag="BSU30260" promotor_-35 2963363..2963370 /Source="Nicolas_upshift_promotors" /id="U2347" /multdbtbs="-" /comp="M2" /sig="SigI" /pcomp="0.72027972027972" /psig="0.72027972027972" /xcortree=350 /SigmaFactorBS="tcaacatgtcaccctgcctacAACATTAAtcgtaagacaaag cTGCGGATGTacagcaaaggaggtgacataagcaaagattcatcacgatgataaggag g" /listShort="msmE, amyD, amyC, melA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2963385..2963393 /Source="Nicolas_upshift_promotors" /id="U2347" /multdbtbs="-" /comp="M2" /sig="SigI" /pcomp="0.72027972027972" /psig="0.72027972027972" /xcortree=350 /SigmaFactorBS="tcaacatgtcaccctgcctacAACATTAAtcgtaagacaaag cTGCGGATGTacagcaaaggaggtgacataagcaaagattcatcacgatgataaggag g" /listShort="msmE, amyD, amyC, melA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2963402 /Source="Nicolas_upshifts" /id="U2347" /multdbtbs="-" /comp="M2" /sig="SigI" /pcomp="0.72027972027972" /psig="0.72027972027972" /xcortree=350 /SigmaFactorBS="tcaacatgtcaccctgcctacAACATTAAtcgtaagacaaag cTGCGGATGTacagcaaaggaggtgacataagcaaagattcatcacgatgataaggag g" /listShort="msmE, amyD, amyC, melA" /GFF_Attribute="listLong" CDS 2963448..2964728 /gene="msmE" /locus_tag="BSU_30270" /old_locus_tag="BSU30270" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 8449892, 12847288, 16707683, 18954360, 28036052; Product type lp : lipoprotein" /codon_start=1 /transl_table=11 /product="multiple sugar-binding lipoprotein" /protein_id="NP_390905.1" /db_xref="EnsemblGenomes-Gn:BSU30270" /db_xref="EnsemblGenomes-Tr:CAB15005" /db_xref="GOA:O34335" /db_xref="InterPro:IPR006059" /db_xref="PDB:4R6H" /db_xref="SubtiList:BG12625" /db_xref="UniProtKB/Swiss-Prot:O34335" /translation="MKHTFVLFLSLILLVLPGCSAEKSSADTAKKTLTIYSTMSTDSE RDTFRKLAAAFEKEHSDIHVSLHFPGNDYENMMRVRMAANDLPDLFDTHGWGKIRYGE YTADLRDMKWTQDLDPNLNSILKNKSGKVYAYPINQAKDGLAYNRNILDRYGIAPPET MDDFIKALRTIKEKSKGSIVPFWFAGYDKSSFAQYYDQFATPLLITDPAHNEKKQLIN GTFQWSKFTYLSEILKQMQKEKLINIDAVTAKKSQLIELMAQNKIAFTMQGGTLGQDV AQINPNVKVGIIPTPAIHPGDDPIWIGGERYTLAAWKDSPQLKEAKDFIAFMARPANA KQMAEATSLPSGLTNVKADIFYANDYEYYQDVKVEPYFDRLYLPNGMWDVLGTVGQEL AADILAPQDISQKLGREYKRLREQSETQGAENNE*" gene 2963448..2964728 /gene="msmE" /locus_tag="BSU_30270" /old_locus_tag="BSU30270" CDS 2964721..2965632 /gene="msmF" /locus_tag="BSU_30280" /old_locus_tag="BSU30280" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 1537846, 12847288, 15849754, 16707683, 16850406; Product type t : transporter" /codon_start=1 /transl_table=11 /product="carbohydrate ABC transporter (permease)" /protein_id="NP_390906.1" /db_xref="EnsemblGenomes-Gn:BSU30280" /db_xref="EnsemblGenomes-Tr:CAB15006" /db_xref="GOA:O34706" /db_xref="InterPro:IPR000515" /db_xref="InterPro:IPR035277" /db_xref="InterPro:IPR035906" /db_xref="SubtiList:BG12565" /db_xref="UniProtKB/Swiss-Prot:O34706" /translation="MSEIARDVHVKQVKPKKQSSLWWMYIPALLSVLVFMIYPFVKGT LITFTNWNGFSQVYQWVGFAQYERLFSDPDTWHILKNTLHYGLGSTFFQNVVGLLYAL LLNQSIKTKAVTRTIVYLPVMISPLIMGYIWYFFFSYDGGALNDLLGVFGISPINALA SPSLNPWIIVMINTYQYVGIAMVVYLAGLQSIPKDYYEAAQMDGAKQGQQFFTITLPL LMPSITINIVINIIGGLKLFDVIIALTAGGPGNASQSMSTFMYDLYFKRQDAGYAATQ GIFMAFVILIISFCALAYFKRKETEMS*" gene 2964721..2965632 /gene="msmF" /locus_tag="BSU_30280" /old_locus_tag="BSU30280" CDS 2965629..2966459 /gene="msmG" /locus_tag="BSU_30290" /old_locus_tag="BSU30290" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 1537846, 15849754, 16707683, 16850406, 22720735; Product type t : transporter" /codon_start=1 /transl_table=11 /product="maltose and multiple sugars ABC transporter (permease)" /protein_id="NP_390907.1" /db_xref="EnsemblGenomes-Gn:BSU30290" /db_xref="EnsemblGenomes-Tr:CAB15007" /db_xref="GOA:O34518" /db_xref="InterPro:IPR000515" /db_xref="InterPro:IPR035906" /db_xref="SubtiList:BG12564" /db_xref="UniProtKB/Swiss-Prot:O34518" /translation="MRAARTKSMRIITLLAAIVACAHFIPFYILLTTSLKAKGDYSSK WIFPADISFHNFSEAWERASLGNSFINTMIITGFSALLLIIFGSLAAYPLARRETKLN KAVFALLISIMIIPPLTSMVPLYRMVVDAGMVNTHAIAIFINTAAYMPLTVFLYSGFI RSTIPKELVEAARIDGAGMLKIFFTIVFPLLKPITATICIISCVFIWNDYQFAIFFLQ DQKVQTLTVAMAGFFGENANNLHLVAAAALMAMLPMVVLFLALQKYFIAGLSSGAVKG *" gene 2965629..2966459 /gene="msmG" /locus_tag="BSU_30290" /old_locus_tag="BSU30290" promotor_-35 2966432..2966436 /Source="Nicolas_upshift_promotors" /id="U2348" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.933066933066933" /psig="0.997002997002997" /xcortree=2740 /SigmaFactorBS="tttttggcgctgcaaaaatactttattgccggCCTGTcttcc ggagcggtaaAGGGTTAACATTAAAGGGGGaagcaatatgaaaaagattacatttatc g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2966452..2966471 /Source="Nicolas_upshift_promotors" /id="U2348" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.933066933066933" /psig="0.997002997002997" /xcortree=2740 /SigmaFactorBS="tttttggcgctgcaaaaatactttattgccggCCTGTcttcc ggagcggtaaAGGGTTAACATTAAAGGGGGaagcaatatgaaaaagattacatttatc g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2966460 /Source="Nicolas_upshifts" /id="U2348" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.933066933066933" /psig="0.997002997002997" /xcortree=2740 /SigmaFactorBS="tttttggcgctgcaaaaatactttattgccggCCTGTcttcc ggagcggtaaAGGGTTAACATTAAAGGGGGaagcaatatgaaaaagattacatttatc g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" CDS 2966479..2967777 /gene="melA" /locus_tag="BSU_30300" /old_locus_tag="BSU30300" /EC_number="3.2.1.22" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2b: Function from indirect experimental evidences (e.g. phenotypes); PubMedId: 12847288; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="alpha-D-galactoside galactohydrolase" /protein_id="NP_390908.1" /db_xref="EnsemblGenomes-Gn:BSU30300" /db_xref="EnsemblGenomes-Tr:CAB15008" /db_xref="GOA:O34645" /db_xref="InterPro:IPR001088" /db_xref="InterPro:IPR015955" /db_xref="InterPro:IPR019802" /db_xref="InterPro:IPR022616" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG12615" /db_xref="UniProtKB/Swiss-Prot:O34645" /translation="MKKITFIGAGSTIFAKNVLGDCLLTEALNGFEFALYDIDPKRLQ ESQLMLENLRDRYNPSVAINSYDDRKLALQNAGYVINAIQVGGYKPSTVIDFEIPKRY GLRQTIADTVGIGGIFRSLRTIPVLFDIAKDMEEMCPDAWFLNYTNPMATLTGAMLRY TNIKTIGLCHSVQVCTKDLFKALGMEHDGIEERIAGINHMAWLLEVKKDGTDLYPEIK RRAKEKQKTKHHDMVRFELMDKFGYYVTESSEHNAEYHPYFIKRNYPELISELQIPLD EYPRRCVKQIENWEKMRDDIVNNKNLTHERSKEYGSRIIEAMETNEPFTFGGNVLNTG LITNLPSKAVVEVTCVADRKKITPCFAGELPEQLAALNRTNINTQLMTIEAAVTRKKE AVYQAAMLDPHTSAELSMKDIISMCDDLFAAHGDWLPEYK*" gene 2966479..2967777 /gene="melA" /locus_tag="BSU_30300" /old_locus_tag="BSU30300" downshifts 2967758 /Source="Nicolas_upshifts" /id="D1557" /incds=0 /nref=12 /ntot=55 /MaxReadThrough="3.99614" /MaxDrop="3.96455" /score="26.0469828" /energy="-11.9" /TU="NA" /idTUdmin="U2346" /TUdmin=0 /isTUend="TRUE" CDS complement(2967799..2968110) /gene="ytwF" /locus_tag="BSU_30310" /old_locus_tag="BSU30310" /EC_number="2.8.1.-" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 10939241, 22730127; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative sulfur transferase" /protein_id="NP_390909.2" /db_xref="EnsemblGenomes-Gn:BSU30310" /db_xref="EnsemblGenomes-Tr:CAB15009" /db_xref="GOA:O32072" /db_xref="InterPro:IPR001763" /db_xref="InterPro:IPR036873" /db_xref="SubtiList:BG13932" /db_xref="UniProtKB/Swiss-Prot:O32072" /translation="MEIKEISTAALKEKIEADEELYLIDVREDEEVAEGMIPQAVHIR MGDIPEKMETLDKDKEYVFICRSGMRSMNVCKYLDEQGFKTVNVEGGMMAWEGETKPK N*" gene complement(2967799..2968110) /gene="ytwF" /locus_tag="BSU_30310" /old_locus_tag="BSU30310" downshifts complement(2967810) /Source="Nicolas_upshifts" /id="D1558" /incds=0 /nref=84 /ntot=254 /MaxReadThrough="2.71726" /MaxDrop="5.77228" /score="23.1306393" /energy="-11.9" /TU="NA" /idTUdmin="U2349" /TUdmin="-20" /isTUend="TRUE" promotor_-10 complement(2968134..2968153) /Source="Nicolas_upshift_promotors" /id="U2349" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.58941058941059" /psig="0.999000999001" /xcortree=1932 /SigmaFactorBS="aaaggggattttttttcatcagtctcaGAATAGCAatcgttc ggctgacTTTGATATACTGAACATGATcactgtgaataggagtgttttctttggaaat a" /listShort="ytwF" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2968142) /Source="Nicolas_upshifts" /id="U2349" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.58941058941059" /psig="0.999000999001" /xcortree=1932 /SigmaFactorBS="aaaggggattttttttcatcagtctcaGAATAGCAatcgttc ggctgacTTTGATATACTGAACATGATcactgtgaataggagtgttttctttggaaat a" /listShort="ytwF" /GFF_Attribute="listLong" promotor_-35 complement(2968168..2968175) /Source="Nicolas_upshift_promotors" /id="U2349" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.58941058941059" /psig="0.999000999001" /xcortree=1932 /SigmaFactorBS="aaaggggattttttttcatcagtctcaGAATAGCAatcgttc ggctgacTTTGATATACTGAACATGATcactgtgaataggagtgttttctttggaaat a" /listShort="ytwF" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 2968176 /Source="Nicolas_upshifts" /id="D1559" /incds=0 /nref=3 /ntot=17 /MaxReadThrough="0.749090000000001" /MaxDrop="4.59307" /score="20.1681452" /energy="-11.2" /TU="NA" /idTUdmin="U2346" /TUdmin=418 /isTUend="FALSE" CDS complement(2968227..2970641) /gene="leuS" /locus_tag="BSU_30320" /old_locus_tag="BSU30320" /EC_number="6.1.1.4" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:12682299, 1317842" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12682299, 1317842; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="leucyl-tRNA synthetase" /protein_id="NP_390910.1" /db_xref="EnsemblGenomes-Gn:BSU30320" /db_xref="EnsemblGenomes-Tr:CAB15010" /db_xref="GOA:P36430" /db_xref="InterPro:IPR001412" /db_xref="InterPro:IPR002300" /db_xref="InterPro:IPR002302" /db_xref="InterPro:IPR009008" /db_xref="InterPro:IPR009080" /db_xref="InterPro:IPR013155" /db_xref="InterPro:IPR014729" /db_xref="InterPro:IPR015413" /db_xref="InterPro:IPR025709" /db_xref="SubtiList:BG10676" /db_xref="UniProtKB/Swiss-Prot:P36430" /translation="MSFQHKEIEKKWQTYWLENKTFATLDNNEKQKFYALDMFPYPSG AGLHVGHPEGYTATDILSRMKRMQGYDVLHPMGWDAFGLPAEQYALDTGNDPAVFTKQ NIDNFRRQIQALGFSYDWDREINTTDPEYYKWTQWIFLKLYEKGLAYVDEVPVNWCPA LGTVLANEEVIDGKSERGGHPVERRPMKQWMLKITAYADRLLEDLEELDWPESIKDMQ RNWIGRSEGAHVHFAIDGHDDSFTVFTTRPDTLFGATYTVLAPEHALVENITTAEQKE AVEAYIKEIQSKSDLERTDLAKTKTGVFTGAYAINPVNGEKLPIWIADYVLASYGTGA VMAVPGHDERDFEFAKTFGLPVKEVVKGGNVEEAAYTGDGEHVNSDFLNGLHKQEAIE KVIAWLEETKNGEKKVTYRLRDWLFSRQRYWGEPIPVIHWEDGTSTAVPEEELPLILP KTDEIKPSGTGESPLANIKEWVEVTDPETGKKGRRETNTMPQWAGSCWYFLRYIDPHN PDQLASPEKLEKWLPVDMYIGGAEHAVLHLLYARFWHKFLYDIGVVPTKEPFQKLYNQ GMILGENNEKMSKSKGNVVNPDEIVASHGADTLRLYEMFMGPLDASIAWSESGLDGAR RFLDRVWRLFIEDSGELNGKIVEGAGETLERVYHETVMKVTDHYEGLRFNTGISQLMV FINEAYKATELPKEYMEGFVKLLSPVAPHLAEELWEKLGHSGTIAYEAWPVYDETKLV DDEVEIVVQLNGKVKAKLQVPADATKEQLEQLAQADEKVKEQLEGKTIRKIIAVPGKL VNIVAN*" gene complement(2968227..2970641) /gene="leuS" /locus_tag="BSU_30320" /old_locus_tag="BSU30320" downshifts complement(2968231) /Source="Nicolas_upshifts" /id="D1560" /incds=0 /nref=115 /ntot=224 /MaxReadThrough="3.2803" /MaxDrop="4.46738" /score="33.3300042" /energy="-11.2" /TU="U2350" /idTUdmin="U2350" /TUdmin="-67" /isTUend="FALSE" S_feature complement(2970642..2970737) /Source="Nicolas_S_feature" /locus_tag="new_3105044_3105139_c" /HighExp="G150, G180, G135, LBGexp, HPh, LBGtran, Paraq, Lbexp, H2O2, dia0" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="SigA" /TUlongPSig="0.989" /label="S1156" misc_RNA complement(2970751..2970965) /gene="tboL" /locus_tag="BSU_misc_RNA_49" /product="T-box riboswitch specific of leucine tRNA ligase" /note="Evidence 2b: Function from indirect experimental evidences (e.g. phenotypes); PubMedId: 1317842, 9098041, 12165569, 12547201, 27169680; Product type n: RNA" /function="16.3: Control" gene complement(2970751..2970965) /gene="tboL" /locus_tag="BSU_misc_RNA_49" downshifts complement(2970782) /Source="Nicolas_upshifts" /id="D1561" /incds=0 /nref=8 /ntot=38 /MaxReadThrough="6.86098" /MaxDrop="4.90189" /score="40.6873438" /energy="-16.7" /TU="U2350" /idTUdmin="U2352" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(2970977..2970996) /Source="Nicolas_upshift_promotors" /id="U2350" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.444555444555445" /psig=1 /xcortree=2672 /SigmaFactorBS="atctccgcccgttcagggtacattcccattgtatacaaacct GCTTGCacttatgaacagaaTTCTATAAAATACAGTTAGAttacggttgcgataagaa c" /listShort="NA, S1156, leuS" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2970998) /Source="Nicolas_upshifts" /id="U2350" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.444555444555445" /psig=1 /xcortree=2672 /SigmaFactorBS="atctccgcccgttcagggtacattcccattgtatacaaacct GCTTGCacttatgaacagaaTTCTATAAAATACAGTTAGAttacggttgcgataagaa c" /listShort="NA, S1156, leuS" /GFF_Attribute="listLong" promotor_-35 2971002..2971007 /Source="Nicolas_upshift_promotors" /id="U2351" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.978021978021978" /psig="0.978021978021978" /xcortree=1009 /SigmaFactorBS="atctaactgtattttatagaattctgTTCATAagtgcaagca ggtttGTATACAATGGGAATGTACcctgaacgggcggagattgaggacaattattcgg g" /listShort="S1157" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 complement(2971011..2971016) /Source="Nicolas_upshift_promotors" /id="U2350" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.444555444555445" /psig=1 /xcortree=2672 /SigmaFactorBS="atctccgcccgttcagggtacattcccattgtatacaaacct GCTTGCacttatgaacagaaTTCTATAAAATACAGTTAGAttacggttgcgataagaa c" /listShort="NA, S1156, leuS" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2971023..2971041 /Source="Nicolas_upshift_promotors" /id="U2351" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.978021978021978" /psig="0.978021978021978" /xcortree=1009 /SigmaFactorBS="atctaactgtattttatagaattctgTTCATAagtgcaagca ggtttGTATACAATGGGAATGTACcctgaacgggcggagattgaggacaattattcgg g" /listShort="S1157" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 2971036..2971476 /Source="Nicolas_S_feature" /locus_tag="new_3105438_3105878" /HighExp="S4, S5, S3, S8, S7, S6, T5.0H, LoTm, C30, M9-stat" /AntisenseName="ytvB" /AntisenseCor="0.57398798861917499" /AntisenseRegPval="-24.2" /CDS_PredictionProba="NA" /TUshortSig="SigEF" /TUshortPSig="0.978" /TUlongSig="NA" /TUlongPSig="NA" /label="S1157" upshifts 2971036 /Source="Nicolas_upshifts" /id="U2351" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.978021978021978" /psig="0.978021978021978" /xcortree=1009 /SigmaFactorBS="atctaactgtattttatagaattctgTTCATAagtgcaagca ggtttGTATACAATGGGAATGTACcctgaacgggcggagattgaggacaattattcgg g" /listShort="S1157" /GFF_Attribute="listLong" CDS complement(2971068..2971403) /gene="ytvB" /locus_tag="BSU_30330" /old_locus_tag="BSU30330" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 16923906; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative conserved membrane protein" /protein_id="NP_390911.3" /db_xref="EnsemblGenomes-Gn:BSU30330" /db_xref="EnsemblGenomes-Tr:CAB15011" /db_xref="GOA:O34881" /db_xref="InterPro:IPR025353" /db_xref="SubtiList:BG13929" /db_xref="UniProtKB/Swiss-Prot:O34881" /translation="MKMLHQVLIACVIGGIMGILGHVKKRGRLEKPRMTKRFIYLGFL EDWFIGMTASILLVLSADPDSGIQLVILSIISGYGGEAVLRSFDFVRELNSGGEPAES KRQTKTPPE*" gene complement(2971068..2971403) /gene="ytvB" /locus_tag="BSU_30330" /old_locus_tag="BSU30330" S_feature complement(2971398..2971662) /Source="Nicolas_S_feature" /locus_tag="new_3105800_3106064_c" /HighExp="S6, S8, S7, Etha, S5, M9-stat, B60, BT, B36, T5.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.989" /TUlongSig="NA" /TUlongPSig="NA" /label="S1158" promotor_-10 complement(2971647..2971666) /Source="Nicolas_upshift_promotors" /id="U2352" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.95004995004995" /psig="0.98901098901099" /xcortree=780 /SigmaFactorBS="aacacatgttctgattcaagcaagtgcagtttgtTGTTTGTC attagggcttgtccTCGTATACACTAAAAATAAGaacagaatttgaacatatgaacgg a" /listShort="S1158, ytvB, NA" /listLong="S1156, leuS" /label="promotor_-10" upshifts complement(2971662) /Source="Nicolas_upshifts" /id="U2352" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.95004995004995" /psig="0.98901098901099" /xcortree=780 /SigmaFactorBS="aacacatgttctgattcaagcaagtgcagtttgtTGTTTGTC attagggcttgtccTCGTATACACTAAAAATAAGaacagaatttgaacatatgaacgg a" /listShort="S1158, ytvB, NA" /listLong="S1156, leuS" promotor_-35 complement(2971681..2971688) /Source="Nicolas_upshift_promotors" /id="U2352" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.95004995004995" /psig="0.98901098901099" /xcortree=780 /SigmaFactorBS="aacacatgttctgattcaagcaagtgcagtttgtTGTTTGTC attagggcttgtccTCGTATACACTAAAAATAAGaacagaatttgaacatatgaacgg a" /listShort="S1158, ytvB, NA" /listLong="S1156, leuS" /label="promotor_-35" promotor_-35 2971701..2971708 /Source="Nicolas_upshift_promotors" /id="U2353" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.887112887112887" /psig="0.997002997002997" /xcortree=2073 /SigmaFactorBS="aatgacaaacaacaaactgcactTGCTTGAAtcagaacatgt gtTGTGCTACGGTTACTGTAGAattcatttttaaaaaggggaatatcaggctttcgca t" /listShort="S1159, ytvA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2971722..2971741 /Source="Nicolas_upshift_promotors" /id="U2353" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.887112887112887" /psig="0.997002997002997" /xcortree=2073 /SigmaFactorBS="aatgacaaacaacaaactgcactTGCTTGAAtcagaacatgt gtTGTGCTACGGTTACTGTAGAattcatttttaaaaaggggaatatcaggctttcgca t" /listShort="S1159, ytvA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2971738 /Source="Nicolas_upshifts" /id="U2353" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.887112887112887" /psig="0.997002997002997" /xcortree=2073 /SigmaFactorBS="aatgacaaacaacaaactgcactTGCTTGAAtcagaacatgt gtTGTGCTACGGTTACTGTAGAattcatttttaaaaaggggaatatcaggctttcgca t" /listShort="S1159, ytvA" /GFF_Attribute="listLong" S_feature 2971740..2971807 /Source="Nicolas_S_feature" /locus_tag="new_3106142_3106209" /HighExp="M40t90, Etha, dia5, HiOs, dia15, H2O2, BC, Diami, M0t90, M9-stat" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.997" /TUlongSig="NA" /TUlongPSig="NA" /label="S1159" CDS 2971808..2972593 /gene="blrA" /locus_tag="BSU_30340" /old_locus_tag="BSU30340" /function="16.3: Control" /function="16.12: Sense" /experiment="publication(s) with functional evidences, PMID:11964249, 16923906, 16923909, 17200735, 17443319, 17575448, 19948797, 21259411, 21851109, 23416074, 24171435, 25211155, 27203230, 28502782, 28632317" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11964249, 16923906, 16923909, 17200735, 17443319, 17575448, 19948797, 21259411, 21851109, 23416074, 24171435, 25211155, 27203230, 28502782, 28632317; Product type rc: receptor" /codon_start=1 /transl_table=11 /product="blue light GTP-binding receptor" /protein_id="NP_390912.1" /db_xref="EnsemblGenomes-Gn:BSU30340" /db_xref="EnsemblGenomes-Tr:CAB15012" /db_xref="GOA:O34627" /db_xref="InterPro:IPR000014" /db_xref="InterPro:IPR000700" /db_xref="InterPro:IPR001610" /db_xref="InterPro:IPR002645" /db_xref="InterPro:IPR035965" /db_xref="InterPro:IPR036513" /db_xref="PDB:1IUM" /db_xref="PDB:2MWG" /db_xref="PDB:2PR5" /db_xref="PDB:2PR6" /db_xref="PDB:4GCZ" /db_xref="SubtiList:BG13928" /db_xref="UniProtKB/Swiss-Prot:O34627" /translation="MASFQSFGIPGQLEVIKKALDHVRVGVVITDPALEDNPIVYVNQ GFVQMTGYETEEILGKNCRFLQGKHTDPAEVDNIRTALQNKEPVTVQIQNYKKDGTMF WNELNIDPMEIEDKTYFVGIQNDITKQKEYEKLLEDSLTEITALSTPIVPIRNGISAL PLVGNLTEERFNSIVCTLTNILSTSKDDYLIIDLSGLAQVNEQTADQIFKLSHLLKLT GTELIITGIKPELAMKMNKLDANFSSLKTYSNVKDAVKVLPIM*" gene 2971808..2972593 /gene="blrA" /locus_tag="BSU_30340" /old_locus_tag="BSU30340" S_feature 2972594..2972650 /Source="Nicolas_S_feature" /locus_tag="new_3106996_3107052" /HighExp="Sw, M40t90, BC, Etha, dia5, dia15, H2O2, Mt0, M0t90, LBGtran" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="NA" /TUshortPSig="NA" /TUlongSig="NA" /TUlongPSig="NA" /label="S1160" CDS complement(2972830..2974023) /gene="yttB" /locus_tag="BSU_30350" /old_locus_tag="BSU30350" /function="16.1: Circulate" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 11988534, 15849754, 16850406, 28472044; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative efflux transporter" /protein_id="NP_390913.1" /db_xref="EnsemblGenomes-Gn:BSU30350" /db_xref="EnsemblGenomes-Tr:CAB15013" /db_xref="GOA:O34546" /db_xref="InterPro:IPR011701" /db_xref="InterPro:IPR020846" /db_xref="InterPro:IPR036259" /db_xref="SubtiList:BG13925" /db_xref="UniProtKB/Swiss-Prot:O34546" /translation="MPRALKILVIGMFINVTGASFLWPLNTIYIHNHLGKSLTVAGLV LMLNSGASVAGNLCGGFLFDKIGGFKSIMLGIAITLASLMGLVFFHDWPAYIVLLTIV GFGSGVVFPASYAMAGSVWPEGGRKAFNAIYVAQNAGVAVGSALGGVVASFSFSYVFL ANAVLYLIFFFIVYFGFRNIQTGDASQTSVLDYDAVNSKAKFAALIILSGGYVLGWLA YSQWSTTIASYTQSIGISLSLYSVLWTVNGILIVLGQPLVSFVVKKWAESLKAQMVIG FIIFIVSFSMLLTAKQFPMFLAAMVILTIGEMLVWPAVPTIANQLAPKGKEGFYQGFV NSAATGGRMIGPLFGGVLVDHYGIRALVLSLLVLLLISIATTLLYDKRIKSAKETNKQ ASISS*" gene complement(2972830..2974023) /gene="yttB" /locus_tag="BSU_30350" /old_locus_tag="BSU30350" downshifts complement(2972850) /Source="Nicolas_upshifts" /id="D1562" /incds=0 /nref=5 /ntot=47 /MaxReadThrough="2.03991" /MaxDrop="3.41948" /score="-7.70376219" /energy="-9.4" /TU="NA" /idTUdmin="U2354" /TUdmin=0 /isTUend="TRUE" S_feature complement(2974024..2974122) /Source="Nicolas_S_feature" /locus_tag="new_3108426_3108524_c" /HighExp="dia15, LBGstat, H2O2, G180, LPhT, Paraq, Oxctl, G150, G135, Diami" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1161" promotor_-10 complement(2974103..2974122) /Source="Nicolas_upshift_promotors" /id="U2354" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.865134865134865" /psig=1 /xcortree=2464 /SigmaFactorBS="atttttcaaacaatatttgttagattttttcacgctcatCAG TTGAAaaatgtgagagagACAGATAGAATGAATGTGCTatgataactggattcgtacg g" /listShort="S1161, yttB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2974122) /Source="Nicolas_upshifts" /id="U2354" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.865134865134865" /psig=1 /xcortree=2464 /SigmaFactorBS="atttttcaaacaatatttgttagattttttcacgctcatCAG TTGAAaaatgtgagagagACAGATAGAATGAATGTGCTatgataactggattcgtacg g" /listShort="S1161, yttB" /GFF_Attribute="listLong" promotor_-35 complement(2974136..2974143) /Source="Nicolas_upshift_promotors" /id="U2354" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.865134865134865" /psig=1 /xcortree=2464 /SigmaFactorBS="atttttcaaacaatatttgttagattttttcacgctcatCAG TTGAAaaatgtgagagagACAGATAGAATGAATGTGCTatgataactggattcgtacg g" /listShort="S1161, yttB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 2974160..2974163 /Source="Nicolas_upshift_promotors" /id="U2355" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.672327672327672" /psig="0.987012987012987" /xcortree=3214 /SigmaFactorBS="tctctctcacatttttcaactgatgagcgtgaaaaaatCTAA caaatattgtttgaAAAATGTAAAATAAATAGAAaaaggggtcatattatggaaatgg t" /listShort="yttA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2974178..2974197 /Source="Nicolas_upshift_promotors" /id="U2355" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.672327672327672" /psig="0.987012987012987" /xcortree=3214 /SigmaFactorBS="tctctctcacatttttcaactgatgagcgtgaaaaaatCTAA caaatattgtttgaAAAATGTAAAATAAATAGAAaaaggggtcatattatggaaatgg t" /listShort="yttA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2974182 /Source="Nicolas_upshifts" /id="U2355" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.672327672327672" /psig="0.987012987012987" /xcortree=3214 /SigmaFactorBS="tctctctcacatttttcaactgatgagcgtgaaaaaatCTAA caaatattgtttgaAAAATGTAAAATAAATAGAAaaaggggtcatattatggaaatgg t" /listShort="yttA" /GFF_Attribute="listLong" CDS 2974212..2974958 /gene="yttA" /locus_tag="BSU_30360" /old_locus_tag="BSU30360" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 12823818" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_390914.2" /db_xref="EnsemblGenomes-Gn:BSU30360" /db_xref="EnsemblGenomes-Tr:CAB15014" /db_xref="GOA:Q795Q5" /db_xref="InterPro:IPR006876" /db_xref="InterPro:IPR035451" /db_xref="SubtiList:BG13924" /db_xref="UniProtKB/Swiss-Prot:Q795Q5" /translation="MEMVLAFLGFLACLIALGYGLYHLVRYVLKKEKRFSKRLFWPLF IGGLVLLFTGAALAEPDTAAANAEKKYSALNAEYKNLTKEHEELEKEYKSVSSEAKKL KDNKEDQDKLEKLKNENSDLKKTQKSLKAEIKELQENQKQLKEDAKTAKAENETLRQD KTKLENQLKETESQTASSHEDTGSSSNNTSKSDETKTADKAEGCNIKGSRNGIYHTPG STYYDRTTDPAEMFCSVEEAEAAGYRAPKR*" gene 2974212..2974958 /gene="yttA" /locus_tag="BSU_30360" /old_locus_tag="BSU30360" downshifts 2974853 /Source="Nicolas_upshifts" /id="D1563" /incds=1 /nref=2 /ntot=94 /MaxReadThrough="4.11368" /MaxDrop="3.01036" /score="23.2955589" /energy="-11.6" /TU="U2355" /idTUdmin="U2355" /TUdmin="-99" /isTUend="FALSE" downshifts 2974952 /Source="Nicolas_upshifts" /id="D1564" /incds=0 /nref=31 /ntot=169 /MaxReadThrough="1.73994" /MaxDrop="4.19129" /score="23.2955589" /energy="-11.6" /TU="NA" /idTUdmin="U2355" /TUdmin=0 /isTUend="TRUE" CDS complement(2974995..2976935) /gene="bceB" /locus_tag="BSU_30370" /old_locus_tag="BSU30370" /function="16.1: Circulate" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:14612242, 15849754, 16850406, 17905982, 25118291" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 14612242, 15849754, 16850406, 17905982, 25118291; Product type t : transporter" /codon_start=1 /transl_table=11 /product="ABC transporter (permease)" /protein_id="NP_390915.1" /db_xref="EnsemblGenomes-Gn:BSU30370" /db_xref="EnsemblGenomes-Tr:CAB15015" /db_xref="GOA:O34741" /db_xref="InterPro:IPR003838" /db_xref="InterPro:IPR027022" /db_xref="SubtiList:BG13921" /db_xref="UniProtKB/Swiss-Prot:O34741" /translation="MNINQLILRNLKKNLRNYYLYVFALIFSVALYFAFVTLQYDPAI NEVKASIKGAAAIKTASILLVAVVAIFILYANTIFIKRRSKEIGLFQLIGMTKHKIFR ILSAENVMLYFGSLAIGVAAGFSISKLVLMILFKIVDVKADAKLHFSEQALVQTVIVF CGIYLLIMIMNYTFIKKQSILSLFKVTSSTEDKVKKISFFQMLIGALGIVLILTGYYV SSELFGGKFKTINELFVAMSFILGSVIIGTFLFYKGSVTFISNIIRKSKGGYLNISEV LSLSSIMFRMKSNALLLTIITTVSALAIGLLSLAYISYYSSEKTAEQNVAADFSFMNE KDAKLFENKLRESNISFVKKATPVLQANVDIANIMDGTPKEMQGDPGNMQLAVVSDKD VKGVDVAAGEAVFSGYTDLLQKIMVFKDSGVIKVKSKHETQPLKYKGLREEFLVSYTF TSGGMPAVIVDDSLFKQLDKDKDPRIQLAQSTFIGVNVKHDDQMEKANELFQQVNKKN EHLSRLDTSAAQKSLFGMVMFIVGFLGLTFLITSGCILYFKQMGESEDEKPSYTILRK LGFTQGDLIKGIRIKQMYNFGIPLVVGLFHSYFAVQSGWFLFGSEVWAPMIMVMVLYT ALYSIFGFLSVLYYKKVIKSSL*" gene complement(2974995..2976935) /gene="bceB" /locus_tag="BSU_30370" /old_locus_tag="BSU30370" downshifts complement(2975006) /Source="Nicolas_upshifts" /id="D1565" /incds=0 /nref=13 /ntot=89 /MaxReadThrough="1.56566" /MaxDrop="4.45006" /score="29.4802229" /energy="-11.6" /TU="NA" /idTUdmin="U2356" /TUdmin=0 /isTUend="TRUE" CDS complement(2976925..2977686) /gene="bceA" /locus_tag="BSU_30380" /old_locus_tag="BSU30380" /function="16.8: Protect" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:14612242, 17905982, 25118291" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 14612242, 17905982, 25118291; Product type t: transporter" /codon_start=1 /transl_table=11 /product="bacitracin ABC efflux transporter (ATP-binding protein)" /protein_id="NP_390916.1" /db_xref="EnsemblGenomes-Gn:BSU30380" /db_xref="EnsemblGenomes-Tr:CAB15016" /db_xref="GOA:O34697" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG13920" /db_xref="UniProtKB/Swiss-Prot:O34697" /translation="MVILEANKIRKSYGNKLNKQEVLKGIDIHIEKGEFVSIMGASGS GKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQLAEFRKQHLGFIFQDYNLLDTLTV KENILLPLSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIH DPSIIFADEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTHDPVAASYCGRVIFIKD GQMYTQLNKGGQDRQTFFQDIMKTQGVLGGVQHEH*" gene complement(2976925..2977686) /gene="bceA" /locus_tag="BSU_30380" /old_locus_tag="BSU30380" misc_feature complement(2977710..2977728) /Source="Nicolas_upshift_promotors" /id="U2356" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.383616383616384" /psig="0.83016983016983" /xcortree=3191 /SigmaFactorBS="gacgaaaatgtcacatgcttttcttttttgttcgccgtatcg aaggaaaagcccggcattcCTTTTTATAATGAGATTATccaatataaaggagactgcg t" /listShort="bceA, bceB" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(2977729) /Source="Nicolas_upshifts" /id="U2356" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.383616383616384" /psig="0.83016983016983" /xcortree=3191 /SigmaFactorBS="gacgaaaatgtcacatgcttttcttttttgttcgccgtatcg aaggaaaagcccggcattcCTTTTTATAATGAGATTATccaatataaaggagactgcg t" /listShort="bceA, bceB" /GFF_Attribute="listLong" CDS complement(2977788..2978792) /gene="bceS" /locus_tag="BSU_30390" /old_locus_tag="BSU30390" /function="16.12: Sense" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:11717295, 17905982, 25118291, 25685323" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11717295, 17905982, 25118291, 25685323; Product type rc: receptor" /codon_start=1 /transl_table=11 /product="two-component sensor histidine kinase controlling resistance to antibiotics affecting the envelope [YtsA]" /protein_id="NP_390917.1" /db_xref="EnsemblGenomes-Gn:BSU30390" /db_xref="EnsemblGenomes-Tr:CAB15017" /db_xref="GOA:O35044" /db_xref="InterPro:IPR003594" /db_xref="InterPro:IPR004358" /db_xref="InterPro:IPR005467" /db_xref="InterPro:IPR036890" /db_xref="SubtiList:BG13919" /db_xref="UniProtKB/Swiss-Prot:O35044" /translation="MIKAFLIERRSWIAAFLFQQALMLFIAFVDPSISFGNVLYMVYL CILFFIIFLWFRYRKETAFYKSLKTWENNLDVTAINEPETPFEAMVERSIAGQTEHLK QTAARHRLALENEKDELMAWIHEVKTPLTAMHLIIDRMEEKALKSQLSYEWLRIHLLL DQQLHQKRISFIENDLSVEFIQLQPLIFKEIKDLQSWCIQKGIGFDIQLEAKEVLSDA KWLAFIIRQLLTNAVKYSEASEIEIKSFQKGEQTQLQVKDCGRGIDPKDVPRIFDKGF TSTTDHHDQASTGMGLYLAKKAAAPLLIHIDVESEFGAGTVFTLTFPIRNQFEHVISV *" gene complement(2977788..2978792) /gene="bceS" /locus_tag="BSU_30390" /old_locus_tag="BSU30390" downshifts complement(2977827) /Source="Nicolas_upshifts" /id="D1566" /incds=0 /nref=25 /ntot=187 /MaxReadThrough="2.40611" /MaxDrop="4.6482" /score="29.3236847" /energy="-13.9" /TU="NA" /idTUdmin="U2357" /TUdmin="-5" /isTUend="TRUE" CDS complement(2978785..2979480) /gene="bceR" /locus_tag="BSU_30400" /old_locus_tag="BSU30400" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:11717295, 17905982, 25118291, 25685323, 27997719" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11717295, 17905982, 25118291, 25685323, 27997719; Product type r: regulator" /codon_start=1 /transl_table=11 /product="two-component response regulator controlling resistance to antibiotics affecting the envelope [YtsB]" /protein_id="NP_390918.1" /db_xref="EnsemblGenomes-Gn:BSU30400" /db_xref="EnsemblGenomes-Tr:CAB15018" /db_xref="GOA:O34951" /db_xref="InterPro:IPR001789" /db_xref="InterPro:IPR001867" /db_xref="InterPro:IPR011006" /db_xref="InterPro:IPR016032" /db_xref="InterPro:IPR036388" /db_xref="SubtiList:BG12340" /db_xref="UniProtKB/Swiss-Prot:O34951" /translation="MFKLLLIEDDESLFHEIKDRLTGWSYDVYGIQDFSQVLQEFAAV NPDCVIIDVQLPKFDGFHWCRLIRSRSNVPILFLSSRDHPADMVMSMQLGADDFIQKP FHFDVLIAKIQAMFRRVHHYNTEPSTIKTWCGAAVDAEQNLVSNDKGSVELTKNEMFI LKQLIEQKNKIVSREELIRSLWNDERFVSDNTLTVNVNRLRKKLDALQLGAYIETKVG QGYIAKEEDKFYD*" gene complement(2978785..2979480) /gene="bceR" /locus_tag="BSU_30400" /old_locus_tag="BSU30400" promotor_-10 complement(2979504..2979522) /Source="Nicolas_upshift_promotors" /id="U2357" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.47952047952048" /psig="0.987012987012987" /xcortree=3119 /SigmaFactorBS="tgcgaacgagccggctgagacagccggctttttctATAGcgc atgctggcgtttTGCTATACACTTGATAAAAaaggaaaaagtgcggtgagtcgattgt t" /listShort="bceR, bceS" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2979516) /Source="Nicolas_upshifts" /id="U2357" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.47952047952048" /psig="0.987012987012987" /xcortree=3119 /SigmaFactorBS="tgcgaacgagccggctgagacagccggctttttctATAGcgc atgctggcgtttTGCTATACACTTGATAAAAaaggaaaaagtgcggtgagtcgattgt t" /listShort="bceR, bceS" /GFF_Attribute="listLong" promotor_-35 complement(2979538..2979541) /Source="Nicolas_upshift_promotors" /id="U2357" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.47952047952048" /psig="0.987012987012987" /xcortree=3119 /SigmaFactorBS="tgcgaacgagccggctgagacagccggctttttctATAGcgc atgctggcgtttTGCTATACACTTGATAAAAaaggaaaaagtgcggtgagtcgattgt t" /listShort="bceR, bceS" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2979577..2980887) /gene="ytrF" /locus_tag="BSU_30410" /old_locus_tag="BSU30410" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:10986249, 15849754, 16850406, 17558661, 22926563" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10986249, 15849754, 16850406, 17558661, 22926563; Product type t : transporter" /codon_start=1 /transl_table=11 /product="metabolite permease involved in resistance to cell wall inhibitors" /protein_id="NP_390919.1" /db_xref="EnsemblGenomes-Gn:BSU30410" /db_xref="EnsemblGenomes-Tr:CAB15019" /db_xref="GOA:O35005" /db_xref="InterPro:IPR003838" /db_xref="InterPro:IPR025857" /db_xref="SubtiList:BG13916" /db_xref="UniProtKB/Swiss-Prot:O35005" /translation="MRFKDQVHFIRRNMKKNRLRVFMTILATTMACAFLVVLSSVGFG IQKTITDMTMSQQIVTKVSVMGKEGDKPIKKADLEKYDHVRSVVERTQVYEPNKATLG NRTNESSNLIFTNMNDELKANMELEKGRVAKSENEIVVGYDFAKRLLTKKESEEYNKK IEEAKGNPEDIKEPKGYTKDILNKTIELSVSKTDSKTGDVTKTKTYDFKIVGITKKPS QDWMEDSNIFISDQFKKDFSEFLDFKGGNVETNIGVFADKFENVEQLTNDLTDDGYYV TSVTTELEGANTFFMVFKIGLIFVGCIAVIISAIGIFNTMTMAVTERTQEIGIMKAIG ASPSIIRRMFLMESAYIGILGCVIGIIISYGVSYLVNLAVPMILAATSGGDAGDLNYT FSYIPASLVIIAVVICGGVAVISGMNPARKATKTNVLTALRREL*" gene complement(2979577..2980887) /gene="ytrF" /locus_tag="BSU_30410" /old_locus_tag="BSU30410" downshifts complement(2979599) /Source="Nicolas_upshifts" /id="D1567" /incds=0 /nref=9 /ntot=170 /MaxReadThrough="4.26891" /MaxDrop="3.83905" /score="28.2472037" /energy="-13.6" /TU="U2359" /idTUdmin="U2359" /TUdmin="-1755" /isTUend="FALSE" CDS complement(2980877..2981572) /gene="ytrE" /locus_tag="BSU_30420" /old_locus_tag="BSU30420" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:10986249, 22720735, 22926563" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10986249, 22720735, 22926563; Product type t: transporter" /codon_start=1 /transl_table=11 /product="ABC transporter (ATP-binding protein) involved in resistance to cell wall inhibitors" /protein_id="NP_390920.1" /db_xref="EnsemblGenomes-Gn:BSU30420" /db_xref="EnsemblGenomes-Tr:CAB15020" /db_xref="GOA:O34392" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR017871" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG13915" /db_xref="UniProtKB/Swiss-Prot:O34392" /translation="MIDVQHIDHSFTIGKKGRENEVPVLKDVSLSVAKGEIACIVGRS GSGKSTLLNLISGYISPTKGRIVINGTDVTGFNEKEWAQFRLDHFGFIFQSFQLIPGL TTYENVEMPLALKGIKPSERKQKVQDMLKRVGLENHAAHYPNELSGGQQQRVSIARAL ILNPSIILADEPTGSLDSETEHEVLELIQQLNRERGITFVIITHDDEVASIGHSKFQL HDGVLKGGITVEV*" gene complement(2980877..2981572) /gene="ytrE" /locus_tag="BSU_30420" /old_locus_tag="BSU30420" CDS complement(2981587..2982564) /gene="ytrD" /locus_tag="BSU_30430" /old_locus_tag="BSU30430" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:10986249, 15849754, 16850406, 17558661, 22926563" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10986249, 15849754, 16850406, 17558661, 22926563; Product type t : transporter" /codon_start=1 /transl_table=11 /product="ABC transporter, permease component involved in resistance to cell wall inhibitors" /protein_id="NP_390921.1" /db_xref="EnsemblGenomes-Gn:BSU30430" /db_xref="EnsemblGenomes-Tr:CAB15021" /db_xref="GOA:O34953" /db_xref="InterPro:IPR023264" /db_xref="SubtiList:BG13914" /db_xref="UniProtKB/Swiss-Prot:O34953" /translation="MPDSGLLYKEWRQNKVALVITILVFILGNPLSILNMYLIYQGCV TGKENWVGPCVFSVDYLNSSFISLFWIWGVVLAVSQLGIERSKSFFDFTLSLPYTRGQ IFHAKFLTGGMVIVVPQLIGYVLSVLLIMLLKPDQAVYFHNYSLGMIIVSMLAYSLVM AGGALTGNSFAQLLVSFTVAISPFLLISLPVINLEILFGGSIDFIHGPVPKWVQYFIP IIYVDSKWAENSPYYLVIPAIMTIIFYIIGYISFVKMSNERNGYFFLWKPLNRPVQII VIIIGIMGFGYFGFTASESFAGYLIGMGTGAVIGFLISYFAIYKKMKLL*" gene complement(2981587..2982564) /gene="ytrD" /locus_tag="BSU_30430" /old_locus_tag="BSU30430" CDS complement(2982594..2983580) /gene="ytrC" /locus_tag="BSU_30440" /old_locus_tag="BSU30440" /experiment="publication(s) with functional evidences, PMID:10986249, 15849754, 16850406, 17558661, 22926563" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10986249, 15849754, 16850406, 17558661, 22926563; Product type t : transporter" /codon_start=1 /transl_table=11 /product="ABC transporter, permease component involved in resistance to cell wall inhibitors" /protein_id="NP_390922.1" /db_xref="EnsemblGenomes-Gn:BSU30440" /db_xref="EnsemblGenomes-Tr:CAB15022" /db_xref="GOA:O34898" /db_xref="InterPro:IPR023264" /db_xref="SubtiList:BG13913" /db_xref="UniProtKB/Swiss-Prot:O34898" /translation="MVDRGLLYREWKQNQVVILLSIAFLVLANPLSIVNTYLSYQGCL DRQDPQYCDFIVNYSISNLIDINWVPGVILAVCFLGMERSKGTMDFILSLPYNRSQIF QTKFWLGGFVIVLSQLIGFLLAWLLILVYNPEHVYFFEHSSIGVIVISFMAFSLVMAA GALTGNAFAQLLTAFSAAILPYLIIALPVGNLEVVFGANIWEIFPSPESYFSLASNLS NLVPISYVVNEWLINSKYLLLIPAVMSMLFYLIGFISFKKLPSERNGHFFLWNRLDRP VQILVMAFGILGFGLFGYYTGHSIIGYILGMIIGAVAGFFVSYFSIYKKTKV*" gene complement(2982594..2983580) /gene="ytrC" /locus_tag="BSU_30440" /old_locus_tag="BSU30440" promotor_-35 2983450..2983459 /Source="Nicolas_upshift_promotors" /id="U2358" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp="0.985014985014985" /psig="0.985014985014985" /xcortree=1713 /SigmaFactorBS="aataattcacaataaaatcacaatattgcgggtcttggcgat caAGACACCCTTgataagacaaatACGTATTAACGATAGAaagcggatttgccaatac t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 2983466 /Source="Nicolas_upshifts" /id="U2358" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp="0.985014985014985" /psig="0.985014985014985" /xcortree=1713 /SigmaFactorBS="aataattcacaataaaatcacaatattgcgggtcttggcgat caAGACACCCTTgataagacaaatACGTATTAACGATAGAaagcggatttgccaatac t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 2983472..2983487 /Source="Nicolas_upshift_promotors" /id="U2358" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp="0.985014985014985" /psig="0.985014985014985" /xcortree=1713 /SigmaFactorBS="aataattcacaataaaatcacaatattgcgggtcttggcgat caAGACACCCTTgataagacaaatACGTATTAACGATAGAaagcggatttgccaatac t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" CDS complement(2983574..2984452) /gene="ytrB" /locus_tag="BSU_30450" /old_locus_tag="BSU30450" /EC_number="3.6.3.-" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:10986249, 22926563" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10986249, 22926563; Product type t: transporter" /codon_start=1 /transl_table=11 /product="ABC transporter (ATP-binding protein) involved in resistance to cell wall inhibitors" /protein_id="NP_390923.1" /db_xref="EnsemblGenomes-Gn:BSU30450" /db_xref="EnsemblGenomes-Tr:CAB15023" /db_xref="GOA:O34641" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG13912" /db_xref="UniProtKB/Swiss-Prot:O34641" /translation="MIELRQLSKAIDGNQVLKDVSLTIEKGEIFGLLGRNGSGKTTML RLIQQIIFADSGTILFDGVEIKKHPKVKQNIIYMPVQNPFYDKYTYKQLVDILRRIYP KFDVTYANELMNRYEIPETKKYRELSTGLKKQLSLVLSFAARPALILLDEPTDGIDAV TRHDVLQLMVDEVAERDTSILITSHRLEDIERMCNRIGFLEDNSLTNVMDLDELKEEY IKIQMAFDTDVNLAIREQNIPMLDQAGVFYTVLIPKSDEEKKSFLRELKPKVWNELPV NLEEVFIAKFGGKRRW*" gene complement(2983574..2984452) /gene="ytrB" /locus_tag="BSU_30450" /old_locus_tag="BSU30450" CDS complement(2984445..2984837) /gene="ytrA" /locus_tag="BSU_30460" /old_locus_tag="BSU30460" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:10986249, 11756427, 17194626, 21856850, 28357385" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10986249, 11756427, 17194626, 21856850, 28357385; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator (GntR family, cell wall antibiotics)" /protein_id="NP_390924.1" /db_xref="EnsemblGenomes-Gn:BSU30460" /db_xref="EnsemblGenomes-Tr:CAB15024" /db_xref="GOA:O34712" /db_xref="InterPro:IPR000524" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG13911" /db_xref="UniProtKB/Swiss-Prot:O34712" /translation="MIQIDPRSSTPIYEQIIQQMKELCLKGIMKPGDKLPSVRELATI IIANPNTVSKAYKELEREGIIETLRGRGTYISENAKTTLVEGKMTMIKEQLKQLIIDA HYAGVELEKLHEWIKEISADVKGGKKND*" gene complement(2984445..2984837) /gene="ytrA" /locus_tag="BSU_30460" /old_locus_tag="BSU30460" S_feature complement(2984838..2985082) /Source="Nicolas_S_feature" /locus_tag="new_3119240_3119484_c" /HighExp="Cold, Salt, SMMPr, MG 15, M9-tran, G180, M9-exp, M/G, MG 25, Oxctl" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.71885600000000005" /TUshortSig="SigA" /TUshortPSig="0.998" /TUlongSig="NA" /TUlongPSig="NA" /label="S1162" CDS complement(2984871..2985008) /locus_tag="BSU_30466" /old_locus_tag="BSU30466" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 28357385" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="YP_009513999.1" /db_xref="EnsemblGenomes-Gn:BSU30466" /db_xref="EnsemblGenomes-Tr:CCQ48604" /db_xref="GOA:L8ECR1" /db_xref="UniProtKB/TrEMBL:L8ECR1" /translation="MKHKKRNKRNVPMLIAASVIACSFFLVLVMIGFEWQKSIIDHFY L*" gene complement(2984871..2985008) /locus_tag="BSU_30466" /old_locus_tag="BSU30466" downshifts 2985006 /Source="Nicolas_upshifts" /id="D1568" /incds=0 /nref=1 /ntot=4 /MaxReadThrough="2.62989" /MaxDrop="3.1332" /score="6.69010243" /energy="-14.4" /TU="NA" /idTUdmin="U2361" /TUdmin="-1254" /isTUend="FALSE" promotor_-10 complement(2985077..2985096) /Source="Nicolas_upshift_promotors" /id="U2359" /multdbtbs="SigA" /comp="M17" /sig="SigA" /pcomp="0.795204795204795" /psig="0.998001998001998" /xcortree=2536 /SigmaFactorBS="gggtccgtttttttgtaaaaaaaggATTGACTTtgtgagtca aagtATTTATTGTATTAAGTGTACtaattgaagtaatacactatagacactaatataa a" /listShort="S1162, ytrA, ytrB, ytrC, ytrD, ytrE, ytrF, bceR, bceS" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2985082) /Source="Nicolas_upshifts" /id="U2359" /multdbtbs="SigA" /comp="M17" /sig="SigA" /pcomp="0.795204795204795" /psig="0.998001998001998" /xcortree=2536 /SigmaFactorBS="gggtccgtttttttgtaaaaaaaggATTGACTTtgtgagtca aagtATTTATTGTATTAAGTGTACtaattgaagtaatacactatagacactaatataa a" /listShort="S1162, ytrA, ytrB, ytrC, ytrD, ytrE, ytrF, bceR, bceS" /GFF_Attribute="listLong" promotor_-35 complement(2985110..2985117) /Source="Nicolas_upshift_promotors" /id="U2359" /multdbtbs="SigA" /comp="M17" /sig="SigA" /pcomp="0.795204795204795" /psig="0.998001998001998" /xcortree=2536 /SigmaFactorBS="gggtccgtttttttgtaaaaaaaggATTGACTTtgtgagtca aagtATTTATTGTATTAAGTGTACtaattgaagtaatacactatagacactaatataa a" /listShort="S1162, ytrA, ytrB, ytrC, ytrD, ytrE, ytrF, bceR, bceS" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(2985163..2985435) /gene="ytzC" /locus_tag="BSU_30470" /old_locus_tag="BSU30470" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_390925.1" /db_xref="EnsemblGenomes-Gn:BSU30470" /db_xref="EnsemblGenomes-Tr:CAB15025" /db_xref="InterPro:IPR019668" /db_xref="SubtiList:BG13937" /db_xref="UniProtKB/Swiss-Prot:O32073" /translation="MATRQSVDEHLQQCMQAYDYAEEQLKIASKQEHYNDQEYSDAQM QLEDAVNALNKLWLSSNDQQREQLYRMRLQLQSLQNNMILQHPLDV*" gene complement(2985163..2985435) /gene="ytzC" /locus_tag="BSU_30470" /old_locus_tag="BSU30470" downshifts complement(2985170) /Source="Nicolas_upshifts" /id="D1569" /incds=0 /nref=1 /ntot=36 /MaxReadThrough="2.96566" /MaxDrop="8.4811" /score="36.3100501" /energy="-14.4" /TU="NA" /idTUdmin="U2360" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(2985475..2985486) /Source="Nicolas_upshift_promotors" /id="U2360" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.743256743256743" /psig="0.743256743256743" /xcortree=824 /SigmaFactorBS="agagaacaaatgaatatcgaccataaattactTTATTGAata aagtcagatgaGGCTACAATATGaatgatggatgatttccattaccaagaggaggggt t" /listShort="ytzC" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 2985479..2985487 /Source="Nicolas_upshift_promotors" /id="U2361" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.724275724275724" /psig="0.724275724275724" /xcortree=1265 /SigmaFactorBS="tgccacagtaacccctcctcttggtaatggaaatcatccatc attcataTTGTAGCCTcatctgactttatTCAATAAAGTAATTTATGGtcgatattca t" /listShort="ytqA" /GFF_Attribute="listLong" /label="promotor_-35" upshifts complement(2985479) /Source="Nicolas_upshifts" /id="U2360" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.743256743256743" /psig="0.743256743256743" /xcortree=824 /SigmaFactorBS="agagaacaaatgaatatcgaccataaattactTTATTGAata aagtcagatgaGGCTACAATATGaatgatggatgatttccattaccaagaggaggggt t" /listShort="ytzC" /GFF_Attribute="listLong" upshifts 2985490 /Source="Nicolas_upshifts" /id="U2361" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.724275724275724" /psig="0.724275724275724" /xcortree=1265 /SigmaFactorBS="tgccacagtaacccctcctcttggtaatggaaatcatccatc attcataTTGTAGCCTcatctgactttatTCAATAAAGTAATTTATGGtcgatattca t" /listShort="ytqA" /GFF_Attribute="listLong" promotor_-10 2985501..2985519 /Source="Nicolas_upshift_promotors" /id="U2361" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.724275724275724" /psig="0.724275724275724" /xcortree=1265 /SigmaFactorBS="tgccacagtaacccctcctcttggtaatggaaatcatccatc attcataTTGTAGCCTcatctgactttatTCAATAAAGTAATTTATGGtcgatattca t" /listShort="ytqA" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 complement(2985501..2985507) /Source="Nicolas_upshift_promotors" /id="U2360" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.743256743256743" /psig="0.743256743256743" /xcortree=824 /SigmaFactorBS="agagaacaaatgaatatcgaccataaattactTTATTGAata aagtcagatgaGGCTACAATATGaatgatggatgatttccattaccaagaggaggggt t" /listShort="ytzC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 2985530..2985535 /Source="Nicolas_upshift_promotors" /id="U2362" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.492507492507492" /psig=1 /xcortree=2496 /SigmaFactorBS="tttattcaataaagtaatttatggtcgatattcaTTTGTTct cttgtgaaatgCGTGCTACAATTTTAGGATGcaatcgtacgcaaggaggcacatgaat t" /listShort="ytqA, ytqB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2985549..2985568 /Source="Nicolas_upshift_promotors" /id="U2362" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.492507492507492" /psig=1 /xcortree=2496 /SigmaFactorBS="tttattcaataaagtaatttatggtcgatattcaTTTGTTct cttgtgaaatgCGTGCTACAATTTTAGGATGcaatcgtacgcaaggaggcacatgaat t" /listShort="ytqA, ytqB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2985556 /Source="Nicolas_upshifts" /id="U2362" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.492507492507492" /psig=1 /xcortree=2496 /SigmaFactorBS="tttattcaataaagtaatttatggtcgatattcaTTTGTTct cttgtgaaatgCGTGCTACAATTTTAGGATGcaatcgtacgcaaggaggcacatgaat t" /listShort="ytqA, ytqB" /GFF_Attribute="listLong" CDS 2985597..2986565 /gene="ytqA" /locus_tag="BSU_30480" /old_locus_tag="BSU30480" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 10413665; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative enzyme" /protein_id="NP_390926.1" /db_xref="EnsemblGenomes-Gn:BSU30480" /db_xref="EnsemblGenomes-Tr:CAB15026" /db_xref="GOA:O35008" /db_xref="InterPro:IPR005911" /db_xref="InterPro:IPR006638" /db_xref="InterPro:IPR007197" /db_xref="InterPro:IPR013785" /db_xref="InterPro:IPR032432" /db_xref="SubtiList:BG13908" /db_xref="UniProtKB/Swiss-Prot:O35008" /translation="MMQNNPFPYSNTEKRYHTLNYHLREHFGHKVFKVALDGGFDCPN RDGTVAHGGCTFCSAAGSGDFAGNRTDDLITQFHDIKNRMHEKWKDGKYIAYFQAFTN THAPVEVLREKFESVLALDDVVGISIATRPDCLPDDVVDYLAELNERTYLWVELGLQT VHERTALLINRAHDFNCYVEGVNKLRKHGIRVCSHIINGLPLEDRDMMMETAKAVADL DVQGIKIHLLHLLKGTPMVKQYEKGKLEFLSQDDYVQLVCDQLEIIPPEMIVHRITGD GPIELMIGPMWSVNKWEVLGAINKELENRGSYQGKFFQRLEEESAL*" gene 2985597..2986565 /gene="ytqA" /locus_tag="BSU_30480" /old_locus_tag="BSU30480" CDS 2986562..2987146 /gene="ytqB" /locus_tag="BSU_30490" /old_locus_tag="BSU30490" /EC_number="2.1.1.-" /function="16.8: Protect" /function="16.2: Construct biomass (Anabolism)" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 16014871, 22333191, 24699744; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative RNA methylase" /protein_id="NP_390927.1" /db_xref="EnsemblGenomes-Gn:BSU30490" /db_xref="EnsemblGenomes-Tr:CAB15027" /db_xref="GOA:O34614" /db_xref="InterPro:IPR010719" /db_xref="InterPro:IPR029063" /db_xref="SubtiList:BG13909" /db_xref="UniProtKB/Swiss-Prot:O34614" /translation="MILKKILPYSKELLKMAAGEGDIVVDATMGNGHDTQFLAELVGE NGHVYAFDIQESAVANTKERLGDMYQARTTLFHKSHDKIAESLPPETHGKVAAAVFNL GYLPGGDKSITTNGSSTIKAIEQLLSIMKDEGLIVLVVYHGHPEGKAEKNDVLEFCRD LDQQTARVLTYGFINQQNDPPFIVAIEKKAQISK*" gene 2986562..2987146 /gene="ytqB" /locus_tag="BSU_30490" /old_locus_tag="BSU30490" downshifts 2987110 /Source="Nicolas_upshifts" /id="D1570" /incds=0 /nref=58 /ntot=249 /MaxReadThrough="2.35311" /MaxDrop="4.47418" /score="22.0352465" /energy="-11.9" /TU="NA" /idTUdmin="U2362" /TUdmin="-8" /isTUend="TRUE" CDS complement(2987136..2988239) /gene="tbcS" /locus_tag="BSU_30500" /old_locus_tag="BSU30500" /EC_number="4.2.3.130" /experiment="publication(s) with functional evidences, PMID:21627333, 24806199" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 21627333, 24806199; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="tetraprenyl-beta-curcumene synthase" /protein_id="NP_390928.1" /db_xref="EnsemblGenomes-Gn:BSU30500" /db_xref="EnsemblGenomes-Tr:CAB15028" /db_xref="GOA:O34707" /db_xref="InterPro:IPR019712" /db_xref="SubtiList:BG13901" /db_xref="UniProtKB/Swiss-Prot:O34707" /translation="MTVPEHPFGLMAKVYRDIFPLVHQELDIWKQKSESIHNSELKAQ ATASIRDKTFHCEGGGILALLSGSQKQKCVEFIIAYQTISDYLDNLCDRSTSLDPQDF RMLHASMQDALTVGAELQNYYQFREEQDDSGYLHELVKTCQRVLGSIEHYDMIKPYLL ELCGYYCDLQVHKHVIEHERVPRLEKWFTQYESELPEMEWYEFSACAGSTLGIFCLVA YSFQPDFTESTAKKIRDSYFPYIQGLHILLDYLIDQEEDLLEGDLNFCSYYQSHEEMM DRLEHFIHKADEHLQGIPHENFHRLINRGLLGVYLSDDKVAGQKEMGRLAKKLIKASG KTSLFFYINGRAYRKFQKMSWMKNSKKKAQIIC*" gene complement(2987136..2988239) /gene="tbcS" /locus_tag="BSU_30500" /old_locus_tag="BSU30500" downshifts complement(2987177) /Source="Nicolas_upshifts" /id="D1571" /incds=0 /nref=35 /ntot=240 /MaxReadThrough="3.47268" /MaxDrop="4.45295" /score="16.7564664" /energy="-10.1" /TU="U2364" /idTUdmin="U2365" /TUdmin="-5" /isTUend="TRUE" CDS complement(2988260..2989039) /gene="ytpA" /locus_tag="BSU_30510" /old_locus_tag="BSU30510" /EC_number="3.1.-.-" /function="16.8: Protect" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:11796336" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11796336; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="phospholipase component of bacilysocin synthesisor export" /protein_id="NP_390929.1" /db_xref="EnsemblGenomes-Gn:BSU30510" /db_xref="EnsemblGenomes-Tr:CAB15029" /db_xref="GOA:O34705" /db_xref="InterPro:IPR000073" /db_xref="InterPro:IPR022742" /db_xref="InterPro:IPR029058" /db_xref="SubtiList:BG13900" /db_xref="UniProtKB/Swiss-Prot:O34705" /translation="MWTWKADRPVAVIVIIHGASEYHGRYKWLIEMWRSSGYHVVMGD LPGQGTTTRARGHIRSFQEYIDEVDAWIDKARTFDLPVFLLGHSMGGLVAIEWVKQQR NPRITGIILSSPCLGLQIKVNKALDLASKGLNVIAPSLKVDSGLSIDMATRNEDVIEA DQNDSLYVRKVSVRWYRELLKTIESAMVPTEAFLKVPLLVMQAGDDKLVDKTMVIKWF NGVASHNKAYREWEGLYHEIFNEPEREDVFKAARAFTDQYI*" gene complement(2988260..2989039) /gene="ytpA" /locus_tag="BSU_30510" /old_locus_tag="BSU30510" promotor_-35 2988682..2988689 /Source="Nicolas_upshift_promotors" /id="U2363" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.632367632367632" /psig="0.962037962037962" /xcortree=2858 /SigmaFactorBS="caagcgctttattcactttaaTTTGCAGTccgagacacggtg aTGATAAAATAATTCCCGTAAtccggggatttctttgctgtttaacccattcaatcgc g" /listShort="ytoA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2988704..2988723 /Source="Nicolas_upshift_promotors" /id="U2363" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.632367632367632" /psig="0.962037962037962" /xcortree=2858 /SigmaFactorBS="caagcgctttattcactttaaTTTGCAGTccgagacacggtg aTGATAAAATAATTCCCGTAAtccggggatttctttgctgtttaacccattcaatcgc g" /listShort="ytoA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2988721 /Source="Nicolas_upshifts" /id="U2363" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.632367632367632" /psig="0.962037962037962" /xcortree=2858 /SigmaFactorBS="caagcgctttattcactttaaTTTGCAGTccgagacacggtg aTGATAAAATAATTCCCGTAAtccggggatttctttgctgtttaacccattcaatcgc g" /listShort="ytoA" /GFF_Attribute="listLong" S_feature complement(2989040..2989619) /Source="Nicolas_S_feature" /locus_tag="new_3123442_3124021_c" /HighExp="dia15, H2O2, Diami, Salt, dia5, M0t90, Lbstat, Etha, Paraq, Lbtran" /AntisenseName="ytoA" /AntisenseCor="-0.44861767737485803" /AntisenseRegPval="-14" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="1, 0.998" /TUlongSig="SigA" /TUlongPSig=1 /label="S1163" CDS 2989088..2989603 /gene="ytoA" /locus_tag="BSU_30520" /old_locus_tag="BSU30520" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 22868757; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative enzyme of the carbonic anhydrase family" /protein_id="NP_390930.1" /db_xref="EnsemblGenomes-Gn:BSU30520" /db_xref="EnsemblGenomes-Tr:CAB15030" /db_xref="GOA:O34696" /db_xref="InterPro:IPR001451" /db_xref="InterPro:IPR011004" /db_xref="SubtiList:BG13896" /db_xref="UniProtKB/Swiss-Prot:O34696" /translation="MIYPYKEHKPDIHPTAFIADNATITGDVVIGEQSSIWFSVVIRG DVAPTRIGNRVNIQDLSCLHQSPNKTLLIEDDATIGHQVTLHSAVIRKNALIGMGSII LDGAEIGEGAFIGAGSLVPPGKIIPPGHLAFGRPAKVIRPLTEEDRKDMQRIRSEYVE KGQYYKFLQQT*" gene 2989088..2989603 /gene="ytoA" /locus_tag="BSU_30520" /old_locus_tag="BSU30520" promotor_-10 complement(2989610..2989629) /Source="Nicolas_upshift_promotors" /id="U2364" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.887112887112887" /psig=1 /xcortree=1919 /SigmaFactorBS="gtatgacgtccgggttaacgatggttattgcTTTCAAATata atttgaaaAATGGTAAAGTAAGACGAAGcaggtcttatgtttgttgaagaaatttata a" /listShort="S1163, ytpA, ytpB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2989619) /Source="Nicolas_upshifts" /id="U2364" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.887112887112887" /psig=1 /xcortree=1919 /SigmaFactorBS="gtatgacgtccgggttaacgatggttattgcTTTCAAATata atttgaaaAATGGTAAAGTAAGACGAAGcaggtcttatgtttgttgaagaaatttata a" /listShort="S1163, ytpA, ytpB" /GFF_Attribute="listLong" S_feature complement(2989621..2989755) /Source="Nicolas_S_feature" /locus_tag="new_3124023_3124157_c" /HighExp="LoTm, Cold, dia5, dia15, Diami, H2O2, S7, G135, G180, G150" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="0.998, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S1164" promotor_-35 complement(2989641..2989648) /Source="Nicolas_upshift_promotors" /id="U2364" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.887112887112887" /psig=1 /xcortree=1919 /SigmaFactorBS="gtatgacgtccgggttaacgatggttattgcTTTCAAATata atttgaaaAATGGTAAAGTAAGACGAAGcaggtcttatgtttgttgaagaaatttata a" /listShort="S1163, ytpA, ytpB" /GFF_Attribute="listLong" /label="promotor_-35" misc_feature complement(2989730..2989749) /Source="Nicolas_upshift_promotors" /id="U2365" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.968031968031968" /psig="0.998001998001998" /xcortree=1850 /SigmaFactorBS="gtgctcatagaaaatagagaacaggaaagaataggtatgtgt ttttgcagaggctgtttatagtttTGTGATAAGATAAAAGTCATacgtttcatgctat a" /listShort="S1164, S1163, ytpA, ytpB" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(2989755) /Source="Nicolas_upshifts" /id="U2365" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.968031968031968" /psig="0.998001998001998" /xcortree=1850 /SigmaFactorBS="gtgctcatagaaaatagagaacaggaaagaataggtatgtgt ttttgcagaggctgtttatagtttTGTGATAAGATAAAAGTCATacgtttcatgctat a" /listShort="S1164, S1163, ytpA, ytpB" /GFF_Attribute="listLong" CDS complement(2989848..2991239) /gene="ytnA" /locus_tag="BSU_30530" /old_locus_tag="BSU30530" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406, 22720735; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative amino acid permease" /protein_id="NP_390931.1" /db_xref="EnsemblGenomes-Gn:BSU30530" /db_xref="EnsemblGenomes-Tr:CAB15031" /db_xref="GOA:O34618" /db_xref="InterPro:IPR002293" /db_xref="InterPro:IPR004840" /db_xref="InterPro:IPR004841" /db_xref="SubtiList:BG13891" /db_xref="UniProtKB/Swiss-Prot:O34618" /translation="MQKQKQELHRGLEERHISLMSLGAAIGVGLFLGSASAIQLAGPG ILVAYAASGLVMFFIMRALGEMAIQKPVAGSFSRYARDYLGPLAGYLTGWNYWFLWVV TCMAEITAVGIYMGFWFPDVPNWIWALSALVIMTGVNFLAVKAYGELEFWFALIKIVA ILSMIAVGLLMIIAGVGNGGIATGISNLWNNGGFFPHGLKGVLLSLQMVMFAYLGIEM IGVTAGEVKNPQKSLAKAIDTVFWRILIFYVGALFVIMSIYPWQEIGSQGSPFVLTFQ KVGIPSAAGIINFVVLTAALSSCNSGIFSTGRMLFNLAEQKEAPQAYGQLTKGGIPGK AVLASAGALLVGVLLNYVVPAKVFTWVTSIATFGAIWTWAIILLSQIKYRKSLKPEEK KQLKYKMPLFPFTSYVSLAFLAFVVILMAYSPDTRVAVIIGPIWFLILLAVYYGKGFH KKNAAAASERNIS*" gene complement(2989848..2991239) /gene="ytnA" /locus_tag="BSU_30530" /old_locus_tag="BSU30530" downshifts complement(2989856) /Source="Nicolas_upshifts" /id="D1572" /incds=0 /nref=133 /ntot=225 /MaxReadThrough="3.05784" /MaxDrop="5.43778" /score="3.82664462" /energy="-7.5" /TU="U2368" /idTUdmin="U2368" /TUdmin="-220" /isTUend="FALSE" S_feature complement(2991240..2991374) /Source="Nicolas_S_feature" /locus_tag="new_3125642_3125776_c" /HighExp="Oxctl, Paraq, Heat, Lbexp, G150, S0, dia0, H2O2, G180, Mal" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1165" CDS complement(2991375..2993273) /gene="asnB" /locus_tag="BSU_30540" /old_locus_tag="BSU30540" /EC_number="2.4.-.-" /EC_number="6.3.5.4" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:10498721, 21949063, 28317238" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10498721, 21949063, 28317238; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="meso-diaminopimelic acid amidotransferase (asparagine synthetase)" /protein_id="NP_390932.1" /db_xref="EnsemblGenomes-Gn:BSU30540" /db_xref="EnsemblGenomes-Tr:CAB15032" /db_xref="GOA:P54420" /db_xref="InterPro:IPR001962" /db_xref="InterPro:IPR006426" /db_xref="InterPro:IPR014729" /db_xref="InterPro:IPR017932" /db_xref="InterPro:IPR029055" /db_xref="InterPro:IPR033738" /db_xref="SubtiList:BG11831" /db_xref="UniProtKB/Swiss-Prot:P54420" /translation="MCGFVGVFNKHPLAQTADQEELIKQMNQMIVHRGPDSDGYFHDE HVGFGFRRLSIIDVENGGQPLSYEDETYWIIFNGEIYNYIELREELEAKGYTFNTDSD TEVLLATYRHYKEEAASKLRGMFAFLIWNKNDHVLYGARDPFGIKPLYYTTINDQVYF ASERKSLMVAQNDIEIDKEALQQYMSFQFVPEPSTLDAHVKKVEPGSQFTIRPDGDIT FKTYFKANFKPVQTEEDKLVKEVRDAIYDSVNVHMRSDVPVGSFLSGGIDSSFIVSVA KEFHPSLKTFSVGFEQQGFSEVDVAKETAAALGIENISKVISPEEYMNELPKIVWHFD DPLADPAAIPLYFVAKEAKKHVTVALSGEGADELFGGYNIYREPLSLKPFERIPSGLK KMLLHVAAVMPEGMRGKSLLERGCTPLQDRYIGNAKIFEESVKKQLLKHYNPNLSYRD VTKTYFTESSSYSDINKMQYVDIHTWMRGDILLKADKMTMANSLELRVPFLDKVVFDV ASKIPDELKTKNGTTKYLLRKAAEGIVPEHVLNRKKLGFPVPIRHWLKNEMNEWVRNI IQESQTDAYIHKDYVLQLLEDHCADKADNSRKIWTVLIFMIWHSINIEKRYMPEELSH QPKEVIFV*" gene complement(2991375..2993273) /gene="asnB" /locus_tag="BSU_30540" /old_locus_tag="BSU30540" promotor_-35 2992431..2992437 /Source="Nicolas_upshift_promotors" /id="U2366" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=950 /SigmaFactorBS="aaagccgacagagaatgtttttaagctTGGATGAaattcctt cgcaacAGACACAATAAAggaagaatcaatcccgccagacaggaacgaaccgacagga a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 2992452..2992463 /Source="Nicolas_upshift_promotors" /id="U2366" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=950 /SigmaFactorBS="aaagccgacagagaatgtttttaagctTGGATGAaattcctt cgcaacAGACACAATAAAggaagaatcaatcccgccagacaggaacgaaccgacagga a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2992464 /Source="Nicolas_upshifts" /id="U2366" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=950 /SigmaFactorBS="aaagccgacagagaatgtttttaagctTGGATGAaattcctt cgcaacAGACACAATAAAggaagaatcaatcccgccagacaggaacgaaccgacagga a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" S_feature complement(2993274..2993397) /Source="Nicolas_S_feature" /locus_tag="new_3127676_3127799_c" /HighExp="Paraq, G135, G180, G150, Oxctl, LBGexp, BMM, dia0, Heat, C30" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigGF, SigA" /TUshortPSig="0.632, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S1166" CDS complement(2993423..2994625) /gene="metK" /locus_tag="BSU_30550" /old_locus_tag="BSU30550" /EC_number="2.5.1.6" /function="16.3: Control" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:8755891, 10094622, 12910260, 16672621, 18634909" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8755891, 10094622, 12910260, 16672621, 18634909; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="S-adenosylmethionine synthetase" /protein_id="NP_390933.1" /db_xref="EnsemblGenomes-Gn:BSU30550" /db_xref="EnsemblGenomes-Tr:CAB15033" /db_xref="GOA:P54419" /db_xref="InterPro:IPR002133" /db_xref="InterPro:IPR022628" /db_xref="InterPro:IPR022629" /db_xref="InterPro:IPR022630" /db_xref="InterPro:IPR022631" /db_xref="InterPro:IPR022636" /db_xref="SubtiList:BG11840" /db_xref="UniProtKB/Swiss-Prot:P54419" /translation="MSKNRRLFTSESVTEGHPDKICDQISDSILDEILKKDPNARVAC ETSVTTGLVLVSGEITTSTYVDIPKTVRQTIKEIGYTRAKYGFDAETCAVLTSIDEQS ADIAMGVDQALEAREGTMSDEEIEAIGAGDQGLMFGYACNETKELMPLPISLAHKLAR RLSEVRKEDILPYLRPDGKTQVTVEYDENNKPVRIDAIVISTQHHPEITLEQIQRNIK EHVINPVVPEELIDEETKYFINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGA FSGKDATKVDRSAAYAARYVAKNIVAAELADSCEVQLAYAIGVAQPVSISINTFGSGK ASEEKLIEVVRNNFDLRPAGIIKMLDLRRPIYKQTAAYGHFGRHDVDLPWERTDKAEQ LRKEALGE*" gene complement(2993423..2994625) /gene="metK" /locus_tag="BSU_30550" /old_locus_tag="BSU30550" downshifts complement(2993442) /Source="Nicolas_upshifts" /id="D1573" /incds=0 /nref=2 /ntot=26 /MaxReadThrough="7.14538" /MaxDrop="3.78097" /score="-4.044113" /energy="-12.1" /TU="U2367,U2368" /idTUdmin="U2367" /TUdmin="-176" /isTUend="FALSE" promotor_-10 complement(2994668..2994679) /Source="Nicolas_upshift_promotors" /id="U2367" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.632367632367632" /psig="0.632367632367632" /xcortree=1447 /SigmaFactorBS="tatgccaattaacattctctaatataactgtacatTGTATAA gagggagcgagttCCGTATCATATAtacaaggtctttcgggaggccttgtgcaggagg a" /listShort="metK, S1166" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2994674) /Source="Nicolas_upshifts" /id="U2367" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.632367632367632" /psig="0.632367632367632" /xcortree=1447 /SigmaFactorBS="tatgccaattaacattctctaatataactgtacatTGTATAA gagggagcgagttCCGTATCATATAtacaaggtctttcgggaggccttgtgcaggagg a" /listShort="metK, S1166" /GFF_Attribute="listLong" S_feature complement(2994676..2994792) /Source="Nicolas_S_feature" /locus_tag="new_3129078_3129194_c" /HighExp="G180, Paraq, G150, Oxctl, G135, BMM, LBGexp, HPh, MG-0.2, GM 25" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1167" promotor_-35 complement(2994693..2994699) /Source="Nicolas_upshift_promotors" /id="U2367" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.632367632367632" /psig="0.632367632367632" /xcortree=1447 /SigmaFactorBS="tatgccaattaacattctctaatataactgtacatTGTATAA gagggagcgagttCCGTATCATATAtacaaggtctttcgggaggccttgtgcaggagg a" /listShort="metK, S1166" /GFF_Attribute="listLong" /label="promotor_-35" misc_RNA complement(2994793..2994931) /gene="mswG" /locus_tag="BSU_misc_RNA_50" /product="S-adenosylmethionine riboswitch" /experiment="publication(s) with functional evidences, PMID:10094622, 12626738, 12910260, 17381305, 18039762" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10094622, 12626738, 12910260, 17381305, 18039762; Product type n: RNA" /function="16.3: Control" gene complement(2994793..2994931) /gene="mswG" /locus_tag="BSU_misc_RNA_50" downshifts 2994891 /Source="Nicolas_upshifts" /id="D1574" /incds=0 /nref=3 /ntot=20 /MaxReadThrough="1.15866" /MaxDrop="4.97875" /score="11.8729615" /energy="-16.6" /TU="NA" /idTUdmin="U2369" /TUdmin="-1841" /isTUend="FALSE" promotor_-10 complement(2994940..2994959) /Source="Nicolas_upshift_promotors" /id="U2368" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.624375624375624" /psig=1 /xcortree=2593 /SigmaFactorBS="ttccctcaatataggtgcctatttcttctgaatcaTATTGac attgcaaaccctttTACGATAAGATATTTCATTGagcggatactcttatcccgagctg g" /listShort="NA, S1167, metK, S1166, asnB, S1165, ytnA, S1164" /listLong="S1163, ytpA, ytpB" /label="promotor_-10" upshifts complement(2994955) /Source="Nicolas_upshifts" /id="U2368" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.624375624375624" /psig=1 /xcortree=2593 /SigmaFactorBS="ttccctcaatataggtgcctatttcttctgaatcaTATTGac attgcaaaccctttTACGATAAGATATTTCATTGagcggatactcttatcccgagctg g" /listShort="NA, S1167, metK, S1166, asnB, S1165, ytnA, S1164" /listLong="S1163, ytpA, ytpB" promotor_-35 complement(2994976..2994980) /Source="Nicolas_upshift_promotors" /id="U2368" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.624375624375624" /psig=1 /xcortree=2593 /SigmaFactorBS="ttccctcaatataggtgcctatttcttctgaatcaTATTGac attgcaaaccctttTACGATAAGATATTTCATTGagcggatactcttatcccgagctg g" /listShort="NA, S1167, metK, S1166, asnB, S1165, ytnA, S1164" /listLong="S1163, ytpA, ytpB" /label="promotor_-35" promotor_-35 2995052..2995059 /Source="Nicolas_upshift_promotors" /id="U2369" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.817182817182817" /psig=1 /xcortree=345 /SigmaFactorBS="gggaaaacaatggaaatgcacacacaaaaaacaataaatagT ATAGACTatttgaaaatataTGTTATACTAATTCACAATTagcaaaacacaaaaaacg a" /listShort="pckA" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 2995071 /Source="Nicolas_upshifts" /id="U2369" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.817182817182817" /psig=1 /xcortree=345 /SigmaFactorBS="gggaaaacaatggaaatgcacacacaaaaaacaataaatagT ATAGACTatttgaaaatataTGTTATACTAATTCACAATTagcaaaacacaaaaaacg a" /listShort="pckA" /GFF_Attribute="listLong" promotor_-10 2995073..2995092 /Source="Nicolas_upshift_promotors" /id="U2369" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.817182817182817" /psig=1 /xcortree=345 /SigmaFactorBS="gggaaaacaatggaaatgcacacacaaaaaacaataaatagT ATAGACTatttgaaaatataTGTTATACTAATTCACAATTagcaaaacacaaaaaacg a" /listShort="pckA" /GFF_Attribute="listLong" /label="promotor_-10" CDS 2995128..2996711 /gene="pckA" /locus_tag="BSU_30560" /old_locus_tag="BSU30560" /EC_number="4.1.1.49" /function="16.2: Construct biomass (Anabolism)" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 1400158, 4146915, 15491857, 15720552, 18586936, 20933603, 23136871; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="phosphoenolpyruvate carboxykinase" /protein_id="NP_390934.2" /db_xref="EnsemblGenomes-Gn:BSU30560" /db_xref="EnsemblGenomes-Tr:CAB15034" /db_xref="GOA:P54418" /db_xref="InterPro:IPR001272" /db_xref="InterPro:IPR008210" /db_xref="InterPro:IPR013035" /db_xref="InterPro:IPR015994" /db_xref="SubtiList:BG11841" /db_xref="UniProtKB/Swiss-Prot:P54418" /translation="MNSVDLTADLQALLTCPNVRHNLSAAQLTEKVLSRNEGILTSTG AVRATTGAYTGRSPKDKFIVEEESTKNKIDWGPVNQPISEEAFERLYTKVVSYLKERD ELFVFEGFAGADEKYRLPITVVNEFAWHNLFARQLFIRPEGNDKKTVEQPFTILSAPH FKADPKTDGTHSETFIIVSFEKRTILIGGTEYAGEMKKSIFSIMNFLLPERDILSMHC SANVGEKGDVALFFGLSGTGKTTLSADADRKLIGDDEHGWSDTGVFNIEGGCYAKCIH LSEEKEPQIFNAIRFGSVLENVVVDEDTREANYDDSFYTENTRAAYPIHMINNIVTPS MAGHPSAIVFLTADAFGVLPPISKLTKEQAMYHFLSGYTSKLAGTERGVTSPETTFST CFGSPFLPLPAHVYAEMLGKKIDEHGADVFLVNTGWTGGGYGTGERMKLSYTRAMVKA AIEGKLEDAEMITDDIFGLHIPAHVPGVPDHILQPENTWTNKEEYKEKAVYLANEFKE NFKKFAHTDAIAQAGGPLV*" gene 2995128..2996711 /gene="pckA" /locus_tag="BSU_30560" /old_locus_tag="BSU30560" downshifts 2996700 /Source="Nicolas_upshifts" /id="D1575" /incds=0 /nref=106 /ntot=269 /MaxReadThrough="2.55056" /MaxDrop="8.3695" /score="11.8729615" /energy="-16.6" /TU="U2369" /idTUdmin="U2369" /TUdmin="-32" /isTUend="FALSE" CDS complement(2996750..2996992) /gene="ytmB" /locus_tag="BSU_30570" /old_locus_tag="BSU30570" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_390935.1" /db_xref="EnsemblGenomes-Gn:BSU30570" /db_xref="EnsemblGenomes-Tr:CAB15035" /db_xref="InterPro:IPR015947" /db_xref="InterPro:IPR019699" /db_xref="PDB:2NWA" /db_xref="SubtiList:BG13882" /db_xref="UniProtKB/Swiss-Prot:O34365" /translation="MGMPVEFNTLIVTKGKEVRIDENIFTLEKDGYRVYPMEIPMDVR KTKFGEKSGTAEVQKLQWEEGRTIITYKLTSLHSVN*" gene complement(2996750..2996992) /gene="ytmB" /locus_tag="BSU_30570" /old_locus_tag="BSU30570" downshifts complement(2996764) /Source="Nicolas_upshifts" /id="D1576" /incds=0 /nref=170 /ntot=242 /MaxReadThrough="1.2088" /MaxDrop="5.1365" /score="38.3436505" /energy="-16.6" /TU="NA" /idTUdmin="U2371" /TUdmin=0 /isTUend="TRUE" CDS complement(2997044..2997817) /gene="ytmA" /locus_tag="BSU_30580" /old_locus_tag="BSU30580" /EC_number="3.1.-.-" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 27899916; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative esterase" /protein_id="NP_390936.1" /db_xref="EnsemblGenomes-Gn:BSU30580" /db_xref="EnsemblGenomes-Tr:CAB15036" /db_xref="GOA:O34493" /db_xref="InterPro:IPR001375" /db_xref="InterPro:IPR002471" /db_xref="InterPro:IPR029058" /db_xref="SubtiList:BG13881" /db_xref="UniProtKB/Swiss-Prot:O34493" /translation="MIVEKRRFPSPSQHVRLYTICYLSNGLRVKGLLAEPAEPGQYDG FLYLRGGIKSVGMVRPGRIIQFASQGFVVFAPFYRGNQGGEGNEDFAGEDREDAFSAF RLLQQHPNVKKDRIHIFGFSRGGIMGMLTAIEMGGQAASFVSWGGVSDMILTYEERQD LRRMMKRVIGGTPKKVPEEYQWRTPFDQVNKIQAPVLLIHGEKDQNVSIQHSYLLEEK LKQLHKPVETWYYSTFTHYFPPKENRRIVRQLTQWMKNR*" gene complement(2997044..2997817) /gene="ytmA" /locus_tag="BSU_30580" /old_locus_tag="BSU30580" S_feature complement(2997818..2997908) /Source="Nicolas_S_feature" /locus_tag="new_3132220_3132310_c" /HighExp="S8, dia15, Diami, Etha, S7, dia5, H2O2, G180, Heat, G135" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.996" /TUlongSig="NA" /TUlongPSig="NA" /label="S1168" promotor_-35 2997884..2997893 /Source="Nicolas_upshift_promotors" /id="U2370" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=1294 /SigmaFactorBS="tttccttactccaaaattacatccggagaacctggttagGCA TTCACACatttttatacccATCATACGATATGTAAAGCAaaaaaggatattaacttga t" /listShort="ytlA, ytlC, ytlD" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(2997897..2997916) /Source="Nicolas_upshift_promotors" /id="U2371" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.79020979020979" /psig="0.996003996003996" /xcortree=2027 /SigmaFactorBS="cacatagacaacctccttatttcgcatcaagtTAATATCCtt ttttgctttacaTATCGTATGATGGGTATAAAaatgtgtgaatgcctaaccaggttct c" /listShort="S1168, ytmA, ytmB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 2997905 /Source="Nicolas_upshifts" /id="U2370" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=1294 /SigmaFactorBS="tttccttactccaaaattacatccggagaacctggttagGCA TTCACACatttttatacccATCATACGATATGTAAAGCAaaaaaggatattaacttga t" /listShort="ytlA, ytlC, ytlD" /GFF_Attribute="listLong" promotor_-10 2997906..2997925 /Source="Nicolas_upshift_promotors" /id="U2370" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=1294 /SigmaFactorBS="tttccttactccaaaattacatccggagaacctggttagGCA TTCACACatttttatacccATCATACGATATGTAAAGCAaaaaaggatattaacttga t" /listShort="ytlA, ytlC, ytlD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(2997910) /Source="Nicolas_upshifts" /id="U2371" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.79020979020979" /psig="0.996003996003996" /xcortree=2027 /SigmaFactorBS="cacatagacaacctccttatttcgcatcaagtTAATATCCtt ttttgctttacaTATCGTATGATGGGTATAAAaatgtgtgaatgcctaaccaggttct c" /listShort="S1168, ytmA, ytmB" /GFF_Attribute="listLong" promotor_-35 complement(2997931..2997938) /Source="Nicolas_upshift_promotors" /id="U2371" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.79020979020979" /psig="0.996003996003996" /xcortree=2027 /SigmaFactorBS="cacatagacaacctccttatttcgcatcaagtTAATATCCtt ttttgctttacaTATCGTATGATGGGTATAAAaatgtgtgaatgcctaaccaggttct c" /listShort="S1168, ytmA, ytmB" /GFF_Attribute="listLong" /label="promotor_-35" CDS 2997968..2998972 /gene="ytlA" /locus_tag="BSU_30595" /old_locus_tag="BSU30595" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative ABC anion transporter component" /protein_id="NP_390937.2" /db_xref="EnsemblGenomes-Gn:BSU30595" /db_xref="EnsemblGenomes-Tr:CAB15037" /db_xref="GOA:C0SP84" /db_xref="SubtiList:BG13873" /db_xref="UniProtKB/Swiss-Prot:C0SP84" /translation="MNRWLRLGFACVGSIFLMFALAACKQEETLTKVKVAEVTHSIFY APLYVAESKGFFKEEGLDVDVNTTWGGDKTMTSLLSNGSDIALVGSETSIYVEAQGAK DPVINFAQLTQTDGTFLVAREDVEHFDWDQLKGKTFLGQRKGGMPQMVGEYVLNKHKI DPHKDIDLIQNIDFANIANAFASGTGEYVQLFEPQASLFEKKGIGHIVASFGEESGEV PYTTFMAKQSYLKKNEDTAVKFTKAIYKAQQWVENHSAKDITDAIKDEFDDTDPDVIE TSIERYKKQHSYSPDPLLNEKEWELLQTIMDKSGELPKHIPYNQLVNKEIAEKVTSEK *" gene 2997968..2998972 /gene="ytlA" /locus_tag="BSU_30595" /old_locus_tag="BSU30595" CDS 2998985..2999767 /gene="ytlC" /locus_tag="BSU_30610" /old_locus_tag="BSU30610" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative ABC anion transporter component, ATP-binding" /protein_id="NP_390939.1" /db_xref="EnsemblGenomes-Gn:BSU30610" /db_xref="EnsemblGenomes-Tr:CAB15039" /db_xref="GOA:O34314" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR017871" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG13875" /db_xref="UniProtKB/Swiss-Prot:O34314" /translation="MSFLHVDHVTHTYFSIKEKTTAVRDIHFDAEKGDFISFLGPSGC GKTTLLSIIAGLIEPSEGRVLIEGREPNQKEHNIGYMLQQDYLFPWKSIEENVLLGLK IADTLTEESKAAALGLLPEFGLIDVEKKYPKELSGGMRQRAALARTLAPNPSLLLLDE PFSALDFQTKLSLENLVFRTLKEYQKTAVLVTHDIGEAIAMSDTIFLFSNQPGTIHQI FTIPKELAAMLPFDARQEPSFQTLFQTIWKELNSLEKQQRNH*" gene 2998985..2999767 /gene="ytlC" /locus_tag="BSU_30610" /old_locus_tag="BSU30610" S_feature complement(2998989..3000537) /Source="Nicolas_S_feature" /locus_tag="new_3133391_3134939_c" /HighExp="Cold, S8, G180, H2O2, G135, Paraq, G150, S7, Oxctl, LPh" /AntisenseName="ytlC" /AntisenseCor="0.110169300738282" /AntisenseRegPval="-1.1000000000000001" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1169" CDS 2999742..3000554 /gene="ytlD" /locus_tag="BSU_30620" /old_locus_tag="BSU30620" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative permease of ABC anion transporter" /protein_id="NP_390940.1" /db_xref="EnsemblGenomes-Gn:BSU30620" /db_xref="EnsemblGenomes-Tr:CAB15040" /db_xref="GOA:O34649" /db_xref="InterPro:IPR000515" /db_xref="InterPro:IPR035906" /db_xref="SubtiList:BG13876" /db_xref="UniProtKB/Swiss-Prot:O34649" /translation="MRNSKETIDLLHEQYQFKQKKEKWKVHSFQLAIFILFFSGWEIS SRQGWIDPLIFSSPSAVWRLLLEKLGDGSLLSHIGVTLFETVLGFLLGTFMGTCLAAL LWWSNRLARILDPYLVILNAMPKVALGPILIVALGPSFISIIAMGAIISVIITTIVVY TAFQEVDENYTKVMKTFGAKKWVIFKEVILPASSPAIISTLKVNVGLSWVGVIVGEFL VSKVGLGYMIIYGFQVFNFTLVFLSLLIIAIFATLMYQGVELLEKKWTKGRT*" gene 2999742..3000554 /gene="ytlD" /locus_tag="BSU_30620" /old_locus_tag="BSU30620" downshifts 3000539 /Source="Nicolas_upshifts" /id="D1577" /incds=0 /nref=1 /ntot=31 /MaxReadThrough="3.58734" /MaxDrop="4.596" /score="38.1379668" /energy="-12.6" /TU="U2370" /idTUdmin="U2370" /TUdmin="-242" /isTUend="FALSE" CDS complement(3000581..3001057) /gene="rppG" /locus_tag="BSU_30630" /old_locus_tag="BSU30630" /EC_number="3.6.1.15" /function="16.6: Maintain" /function="16.3: Control" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:15576788, 16513759, 21925382, 23610407, 23610425, 27936487" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15576788, 16513759, 21925382, 23610407, 23610425, 27936487; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="nucleoside and RNA triphosphate phosphohydrolase" /protein_id="NP_390941.1" /db_xref="EnsemblGenomes-Gn:BSU30630" /db_xref="EnsemblGenomes-Tr:CAB15041" /db_xref="GOA:O35013" /db_xref="InterPro:IPR000086" /db_xref="InterPro:IPR014078" /db_xref="InterPro:IPR015797" /db_xref="InterPro:IPR020084" /db_xref="InterPro:IPR020476" /db_xref="PDB:4JZS" /db_xref="PDB:4JZT" /db_xref="PDB:4JZU" /db_xref="PDB:4JZV" /db_xref="SubtiList:BG13869" /db_xref="UniProtKB/Swiss-Prot:O35013" /translation="MYEFKDYYQNTVQLSFDDQPFSDSPKHVWVICRFGGKWLLTEHE DRGYEFPGGKVEPMECAEEAALREVKEETGARVKSLKYLGQYKVLGKEKVIVKNIYFA DIEKLEKQADYFETKGPVLFHELPENLSRNKKFSFIMKDSVLPISLKKLKESGWIE*" gene complement(3000581..3001057) /gene="rppG" /locus_tag="BSU_30630" /old_locus_tag="BSU30630" downshifts complement(3000582) /Source="Nicolas_upshifts" /id="D1578" /incds=0 /nref=171 /ntot=265 /MaxReadThrough="4.52721" /MaxDrop="6.99686" /score="36.2618206" /energy="-12.6" /TU="U2372" /idTUdmin="U2373" /TUdmin=11 /isTUend="TRUE" misc_feature complement(3001087..3001106) /Source="Nicolas_upshift_promotors" /id="U2372" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.935064935064935" /psig=1 /xcortree=2134 /SigmaFactorBS="cggcgtgctgggtttcccttattttttgataaaaggcttccg aagaaacgtaacTGTGGTATGATGTATGGAAGatagctaggaacggatttgagggata a" /listShort="ytkD, S1169" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(3001100) /Source="Nicolas_upshifts" /id="U2372" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.935064935064935" /psig=1 /xcortree=2134 /SigmaFactorBS="cggcgtgctgggtttcccttattttttgataaaaggcttccg aagaaacgtaacTGTGGTATGATGTATGGAAGatagctaggaacggatttgagggata a" /listShort="ytkD, S1169" /GFF_Attribute="listLong" S_feature complement(3001102..3001236) /Source="Nicolas_S_feature" /locus_tag="new_3135504_3135638_c" /HighExp="BT, B36, S8, S5, S7, Etha, S6, S4, B60, LoTm" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigGF, SigK, SigB" /TUshortPSig="0.909, 1, 0.994" /TUlongSig="SigA, SigA" /TUlongPSig="0.999, 0.994" /label="S1170" upshifts complement(3001236) /Source="Nicolas_upshifts" /id="U2373" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.909090909090909" /psig="0.909090909090909" /xcortree=1213 /SigmaFactorBS="gttaaaaaataaatttaagcgcaaacCGTAACTtttccctgt tcgcgGGTCATAATAAAgcccagagcgtcggtcgcactttccggcaaaagtatcgcaa a" /listShort="S1170, ytkD" /GFF_Attribute="listLong" promotor_-10 complement(3001238..3001249) /Source="Nicolas_upshift_promotors" /id="U2373" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.909090909090909" /psig="0.909090909090909" /xcortree=1213 /SigmaFactorBS="gttaaaaaataaatttaagcgcaaacCGTAACTtttccctgt tcgcgGGTCATAATAAAgcccagagcgtcggtcgcactttccggcaaaagtatcgcaa a" /listShort="S1170, ytkD" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 complement(3001264..3001270) /Source="Nicolas_upshift_promotors" /id="U2373" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.909090909090909" /psig="0.909090909090909" /xcortree=1213 /SigmaFactorBS="gttaaaaaataaatttaagcgcaaacCGTAACTtttccctgt tcgcgGGTCATAATAAAgcccagagcgtcggtcgcactttccggcaaaagtatcgcaa a" /listShort="S1170, ytkD" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3001266..3001670) /gene="ytkC" /locus_tag="BSU_30640" /old_locus_tag="BSU30640" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type h: extrachromosomal origin" /codon_start=1 /transl_table=11 /product="putative autolytic amidase" /protein_id="NP_390942.1" /db_xref="EnsemblGenomes-Gn:BSU30640" /db_xref="EnsemblGenomes-Tr:CAB15042" /db_xref="GOA:O34883" /db_xref="InterPro:IPR006480" /db_xref="SubtiList:BG13868" /db_xref="UniProtKB/Swiss-Prot:O34883" /translation="MDRDFGIFSFLAVSVSAAGFFFGGFQYSFLILLSLMAIEFISTT LKETIIHKLSFKKVFARLVKKLVTLALISVCHFFDQLLNTQGSIRDLAIMFYILYESV QIVVTASSLGIPVPQMLVDLLETLKNKFKRKP*" gene complement(3001266..3001670) /gene="ytkC" /locus_tag="BSU_30640" /old_locus_tag="BSU30640" promotor_-10 complement(3001698..3001717) /Source="Nicolas_upshift_promotors" /id="U2374" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1424 /SigmaFactorBS="gaaaaataggcgacaaccagtccatttttctgaaaaATCCAA TCCGttcggcttgtttACCATAGAATATCGTAAGGCcgtttctgtgaaaggatgttgg g" /listShort="ytkC, S1170, ytkD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3001715) /Source="Nicolas_upshifts" /id="U2374" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1424 /SigmaFactorBS="gaaaaataggcgacaaccagtccatttttctgaaaaATCCAA TCCGttcggcttgtttACCATAGAATATCGTAAGGCcgtttctgtgaaaggatgttgg g" /listShort="ytkC, S1170, ytkD" /GFF_Attribute="listLong" S_feature complement(3001717..3001803) /Source="Nicolas_S_feature" /locus_tag="new_3136119_3136205_c" /HighExp="Etha, B36, S8, B60, S7, LoTm, Salt, Sw, Gly, Lbstat" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigB" /TUshortPSig="0.994" /TUlongSig="SigA, SigA" /TUlongPSig="0.999, 0.994" /label="S1171" promotor_-35 complement(3001730..3001739) /Source="Nicolas_upshift_promotors" /id="U2374" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1424 /SigmaFactorBS="gaaaaataggcgacaaccagtccatttttctgaaaaATCCAA TCCGttcggcttgtttACCATAGAATATCGTAAGGCcgtttctgtgaaaggatgttgg g" /listShort="ytkC, S1170, ytkD" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3001836..3002273) /gene="dps" /locus_tag="BSU_30650" /old_locus_tag="BSU30650" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1c: Function from experimental evidences in the studied genus; PubMedId: 12767829, 16091047, 16861227, 16935006; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="DNA-protecting protein, mini-ferritin" /protein_id="NP_390943.1" /db_xref="EnsemblGenomes-Gn:BSU30650" /db_xref="EnsemblGenomes-Tr:CAB15043" /db_xref="GOA:P80879" /db_xref="InterPro:IPR002177" /db_xref="InterPro:IPR008331" /db_xref="InterPro:IPR009078" /db_xref="InterPro:IPR012347" /db_xref="InterPro:IPR023188" /db_xref="SubtiList:BG12584" /db_xref="UniProtKB/Swiss-Prot:P80879" /translation="MSEQLIQAVNKQVANWTVMYVKLHNYHWYVKGKDFFTLHEKFEE LYNETATYIDDLAERLLALNGKPIATMKESLETASVKEAAGNETAEQMVQSVYDDFTV IAEELKNGMDLADEVGDETTGDMLLAIHQNIEKHNWMLKAYLG*" gene complement(3001836..3002273) /gene="dps" /locus_tag="BSU_30650" /old_locus_tag="BSU30650" downshifts complement(3001848) /Source="Nicolas_upshifts" /id="D1579" /incds=0 /nref=188 /ntot=382 /MaxReadThrough="3.87056" /MaxDrop="7.83664" /score="36.0931083" /energy="-19.2" /TU="U2375" /idTUdmin="U2377" /TUdmin="-1" /isTUend="TRUE" promotor_-10 complement(3002290..3002308) /Source="Nicolas_upshift_promotors" /id="U2375" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp="0.994005994005994" /psig="0.994005994005994" /xcortree=143 /SigmaFactorBS="cataatagaagaaatcgtgacagataagggtaaaaaagaGGT TTTAgcgtacgatattaaGGGTATACATAGTCATATAacaaggaggagataccatgtc a" /listShort="dps, S1171, ytkC, S1170, ytkD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3002308) /Source="Nicolas_upshifts" /id="U2375" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp="0.994005994005994" /psig="0.994005994005994" /xcortree=143 /SigmaFactorBS="cataatagaagaaatcgtgacagataagggtaaaaaagaGGT TTTAgcgtacgatattaaGGGTATACATAGTCATATAacaaggaggagataccatgtc a" /listShort="dps, S1171, ytkC, S1170, ytkD" /GFF_Attribute="listLong" S_feature complement(3002310..3002535) /Source="Nicolas_S_feature" /locus_tag="new_3136712_3136937_c" /HighExp="M0t90, Lbstat, M40t90, ferm, S2, nit, M40t45, S0, Lbtran, BT" /AntisenseName="ytzI" /AntisenseCor="-0.30531150128448598" /AntisenseRegPval="-6.5" /CDS_PredictionProba="0.38276900000000003" /TUshortSig="SigA, SigA, SigA" /TUshortPSig="0.999, 0.999, 0.994" /TUlongSig="NA" /TUlongPSig="NA" /label="S1172" promotor_-35 complement(3002323..3002329) /Source="Nicolas_upshift_promotors" /id="U2375" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp="0.994005994005994" /psig="0.994005994005994" /xcortree=143 /SigmaFactorBS="cataatagaagaaatcgtgacagataagggtaaaaaagaGGT TTTAgcgtacgatattaaGGGTATACATAGTCATATAacaaggaggagataccatgtc a" /listShort="dps, S1171, ytkC, S1170, ytkD" /GFF_Attribute="listLong" /label="promotor_-35" misc_feature 3002365..3002384 /Source="Nicolas_upshift_promotors" /id="U2376" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.94005994005994" /psig="0.999000999001" /xcortree=436 /SigmaFactorBS="ccttaatatcgtacgctaaaacctcttttttacccttatctg tcacgatttcttctatTATGCTACAATTGTTAAAAAacgggaggtggaatgtcatgac g" /listShort="ytzI" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" CDS 3002366..3002542 /gene="ytzI" /locus_tag="BSU_30659" /old_locus_tag="BSU30659" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="YP_003097774.1" /db_xref="EnsemblGenomes-Gn:BSU30659" /db_xref="EnsemblGenomes-Tr:CAX52680" /db_xref="GOA:C0H3Q1" /db_xref="InterPro:IPR022248" /db_xref="UniProtKB/Swiss-Prot:C0H3Q1" /translation="MLQLLKNGRWNVMTLLITISILIVLAVLLVTIWTTVKAYNVKHT IDPPQENHSDSHNQ*" gene 3002366..3002542 /gene="ytzI" /locus_tag="BSU_30659" /old_locus_tag="BSU30659" upshifts 3002367 /Source="Nicolas_upshifts" /id="U2376" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.94005994005994" /psig="0.999000999001" /xcortree=436 /SigmaFactorBS="ccttaatatcgtacgctaaaacctcttttttacccttatctg tcacgatttcttctatTATGCTACAATTGTTAAAAAacgggaggtggaatgtcatgac g" /listShort="ytzI" /GFF_Attribute="listLong" CDS complement(3002536..3002973) /gene="ytkA" /locus_tag="BSU_30660" /old_locus_tag="BSU30660" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type lp: lipoprotein" /codon_start=1 /transl_table=11 /product="putative lipoprotein" /protein_id="NP_390944.1" /db_xref="EnsemblGenomes-Gn:BSU30660" /db_xref="EnsemblGenomes-Tr:CAB15044" /db_xref="InterPro:IPR013783" /db_xref="InterPro:IPR032693" /db_xref="SubtiList:BG11027" /db_xref="UniProtKB/Swiss-Prot:P40768" /translation="MKKMLVVLLFSALLLNGCGSGESKANTAETPEVLDVKLTGPEKV NPGESAAYEAAVSYGDEAVTDADEVEFEVWKEGEKDASQMFKVKQEKGVYRLETTFKE DGVYTVQSHVTAKKQHSMPTLKVQVGDADAASNQSEEEHSHHH*" gene complement(3002536..3002973) /gene="ytkA" /locus_tag="BSU_30660" /old_locus_tag="BSU30660" downshifts 3002562 /Source="Nicolas_upshifts" /id="D1580" /incds=0 /nref=37 /ntot=155 /MaxReadThrough="2.0116" /MaxDrop="3.95427" /score="13.1411485" /energy="-20.5" /TU="NA" /idTUdmin="U2376" /TUdmin="-1" /isTUend="TRUE" promotor_-10 complement(3002992..3003011) /Source="Nicolas_upshift_promotors" /id="U2377" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.892107892107892" /psig="0.999000999001" /xcortree=1608 /SigmaFactorBS="cgcttaagcaaaaaggtcttttttgtgacgtctcatattttg tGTACCATTTgctgtaagcgTTTGCTACTATTTAGGTAAAcgatgaaagggtgatggc a" /listShort="ytkA, S1172, dps" /listLong="S1171, ytkC, S1170, ytkD" /label="promotor_-10" upshifts complement(3003013) /Source="Nicolas_upshifts" /id="U2377" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.892107892107892" /psig="0.999000999001" /xcortree=1608 /SigmaFactorBS="cgcttaagcaaaaaggtcttttttgtgacgtctcatattttg tGTACCATTTgctgtaagcgTTTGCTACTATTTAGGTAAAcgatgaaagggtgatggc a" /listShort="ytkA, S1172, dps" /listLong="S1171, ytkC, S1170, ytkD" promotor_-35 complement(3003022..3003030) /Source="Nicolas_upshift_promotors" /id="U2377" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.892107892107892" /psig="0.999000999001" /xcortree=1608 /SigmaFactorBS="cgcttaagcaaaaaggtcttttttgtgacgtctcatattttg tGTACCATTTgctgtaagcgTTTGCTACTATTTAGGTAAAcgatgaaagggtgatggc a" /listShort="ytkA, S1172, dps" /listLong="S1171, ytkC, S1170, ytkD" /label="promotor_-35" CDS complement(3003093..3003566) /gene="luxS" /locus_tag="BSU_30670" /old_locus_tag="BSU30670" /EC_number="4.4.1.21" /function="16.5: Explore" /function="16.3: Control" /function="16.12: Sense" /experiment="publication(s) with functional evidences, PMID:11601850, 15287744, 15751951, 16740951, 17056751, 22720735, 22938038, 26779171, 28342077" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11601850, 15287744, 15751951, 16740951, 17056751, 22720735, 22938038, 26779171, 28342077; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="S-ribosylhomocysteine lyase" /protein_id="NP_390945.1" /db_xref="EnsemblGenomes-Gn:BSU30670" /db_xref="EnsemblGenomes-Tr:CAB15045" /db_xref="GOA:O34667" /db_xref="InterPro:IPR003815" /db_xref="InterPro:IPR011249" /db_xref="InterPro:IPR037005" /db_xref="PDB:1IE0" /db_xref="PDB:1J98" /db_xref="PDB:1JQW" /db_xref="PDB:1JVI" /db_xref="PDB:1YCL" /db_xref="PDB:2FQO" /db_xref="PDB:2FQT" /db_xref="SubtiList:BG13866" /db_xref="UniProtKB/Swiss-Prot:O34667" /translation="MPSVESFELDHNAVVAPYVRHCGVHKVGTDGVVNKFDIRFCQPN KQAMKPDTIHTLEHLLAFTIRSHAEKYDHFDIIDISPMGCQTGYYLVVSGEPTSAEIV DLLEDTMKEAVEITEIPAANEKQCGQAKLHDLEGAKRLMRFWLSQDKEELLKVFG*" gene complement(3003093..3003566) /gene="luxS" /locus_tag="BSU_30670" /old_locus_tag="BSU30670" downshifts complement(3003102) /Source="Nicolas_upshifts" /id="D1581" /incds=0 /nref=72 /ntot=201 /MaxReadThrough="4.53626" /MaxDrop="4.63695" /score="14.8438415" /energy="-14.2" /TU="U2379,U2380" /idTUdmin="U2380" /TUdmin="-793" /isTUend="FALSE" downshifts complement(3003189) /Source="Nicolas_upshifts" /id="D1582" /incds=1 /nref=1 /ntot=96 /MaxReadThrough="5.57623" /MaxDrop="2.4806" /score="14.8438415" /energy="-14.2" /TU="U2379,U2380" /idTUdmin="U2380" /TUdmin="-880" /isTUend="FALSE" S_feature complement(3003567..3003918) /Source="Nicolas_S_feature" /locus_tag="new_3137969_3138320_c" /HighExp="Etha, B36, B60, BMM, S2, Heat, S1, LoTm, Lbtran, S5" /AntisenseName="ytjA" /AntisenseCor="-0.45038987072908898" /AntisenseRegPval="-14.1" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="0.999, 0.994" /TUlongSig="NA" /TUlongPSig="NA" /label="S1173" promotor_-35 3003638..3003645 /Source="Nicolas_upshift_promotors" /id="U2378" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.553446553446553" /psig="0.999000999001" /xcortree=2863 /SigmaFactorBS="ttataacatacttttccgataagaattattgattaACTTTTC AatctgtgtttttTTTCTTATACTTGCATCAGAaaggttgctgaagaaacatgaaaac c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3003658..3003677 /Source="Nicolas_upshift_promotors" /id="U2378" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.553446553446553" /psig="0.999000999001" /xcortree=2863 /SigmaFactorBS="ttataacatacttttccgataagaattattgattaACTTTTC AatctgtgtttttTTTCTTATACTTGCATCAGAaaggttgctgaagaaacatgaaaac c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3003663 /Source="Nicolas_upshifts" /id="U2378" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.553446553446553" /psig="0.999000999001" /xcortree=2863 /SigmaFactorBS="ttataacatacttttccgataagaattattgattaACTTTTC AatctgtgtttttTTTCTTATACTTGCATCAGAaaggttgctgaagaaacatgaaaac c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" CDS 3003695..3003922 /gene="ytjA" /locus_tag="BSU_30680" /old_locus_tag="BSU30680" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 19306042, 21803992; Product type f: factor" /codon_start=1 /transl_table=11 /product="membrane protein insertion efficiency factor" /protein_id="NP_390946.1" /db_xref="EnsemblGenomes-Gn:BSU30680" /db_xref="EnsemblGenomes-Tr:CAB15046" /db_xref="GOA:O34601" /db_xref="InterPro:IPR002696" /db_xref="SubtiList:BG13865" /db_xref="UniProtKB/Swiss-Prot:O34601" /translation="MKTLFIALIRGYQKFISPLTPPTCRFYPTCSQYGIEAIKTHGAL KGGWLTIKRILKCHPFHPGGVDPVPEKKQKH*" gene 3003695..3003922 /gene="ytjA" /locus_tag="BSU_30680" /old_locus_tag="BSU30680" CDS complement(3003919..3004482) /gene="ytiB" /locus_tag="BSU_30690" /old_locus_tag="BSU30690" /EC_number="4.2.1.1" /function="16.11: Scavenge (Catabolism)" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 12193617, 21266987; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="carbonic anhydrase" /protein_id="NP_390947.1" /db_xref="EnsemblGenomes-Gn:BSU30690" /db_xref="EnsemblGenomes-Tr:CAB15047" /db_xref="GOA:O34872" /db_xref="InterPro:IPR001765" /db_xref="InterPro:IPR036874" /db_xref="SubtiList:BG13863" /db_xref="UniProtKB/Swiss-Prot:O34872" /translation="MSLLNDILEFNKTFTEQREYEKYQTSKFPDKKMAILSCMDTRLV ELLPHAMNLRNGDVKIIKSAGALVTHPFGSIMRSILVAVYELNADEVCVIGHHDCGMS KISSKSMLEKIKARGIPEERIETIKYSGVDFDQWFKSFDSVEASVKDSVDVIKHHPLF PENVPVHGLVIDPKTGKLDLIVNGYNN*" gene complement(3003919..3004482) /gene="ytiB" /locus_tag="BSU_30690" /old_locus_tag="BSU30690" misc_feature complement(3004507..3004526) /Source="Nicolas_upshift_promotors" /id="U2379" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.718281718281718" /psig="0.999000999001" /xcortree=2374 /SigmaFactorBS="gaaataaggcaggcctgagggtttgtctttttttattatgac gaataaacaagggtTGTGATATATTGAAGAGTAAaaagaatagaaagggacaacgaac a" /listShort="ytiB, S1173, luxS, ytkA, S1172, dps" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(3004522) /Source="Nicolas_upshifts" /id="U2379" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.718281718281718" /psig="0.999000999001" /xcortree=2374 /SigmaFactorBS="gaaataaggcaggcctgagggtttgtctttttttattatgac gaataaacaagggtTGTGATATATTGAAGAGTAAaaagaatagaaagggacaacgaac a" /listShort="ytiB, S1173, luxS, ytkA, S1172, dps" /GFF_Attribute="listLong" CDS complement(3004576..3004824) /gene="rpmEB" /locus_tag="BSU_30700" /old_locus_tag="BSU30700" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:15049826, 16014871, 16547061, 19648245, 20208344" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15049826, 16014871, 16547061, 19648245, 20208344; Product type f: factor" /codon_start=1 /transl_table=11 /product="ribosomal protein L31" /protein_id="NP_390948.1" /db_xref="EnsemblGenomes-Gn:BSU30700" /db_xref="EnsemblGenomes-Tr:CAB15048" /db_xref="GOA:O34967" /db_xref="InterPro:IPR002150" /db_xref="InterPro:IPR027493" /db_xref="InterPro:IPR034704" /db_xref="SubtiList:BG13862" /db_xref="UniProtKB/Swiss-Prot:O34967" /translation="MKEGIHPKNHKVIFQDVNSGYRFLSTSTKTSNETAEWEDGNTYP VIKVEVSSDTHPFYTGRQKFNEKGGRVEQFKKRYNMGK*" gene complement(3004576..3004824) /gene="rpmEB" /locus_tag="BSU_30700" /old_locus_tag="BSU30700" downshifts complement(3004597) /Source="Nicolas_upshifts" /id="D1583" /incds=0 /nref=96 /ntot=217 /MaxReadThrough="7.96356" /MaxDrop="4.50701" /score="15.8096104" /energy="-7.5" /TU="U2380" /idTUdmin="U2380" /TUdmin="-2288" /isTUend="FALSE" promotor_-10 complement(3004852..3004871) /Source="Nicolas_upshift_promotors" /id="U2380" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.571428571428571" /psig="0.994005994005994" /xcortree=663 /SigmaFactorBS="cctattcttaaatgccatgaggtttacgatgtgaaacagagg gaaggatataagaagATTGACAAaacgtttgtaaggTTATAAAATAAAACGTAATTat t" /listShort="rpmEB, ytiB, S1173, luxS, ytkA, S1172" /listLong="dps, S1171, ytkC, S1170, ytkD" /label="promotor_-10" promotor_-35 complement(3004885..3004892) /Source="Nicolas_upshift_promotors" /id="U2380" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.571428571428571" /psig="0.994005994005994" /xcortree=663 /SigmaFactorBS="cctattcttaaatgccatgaggtttacgatgtgaaacagagg gaaggatataagaagATTGACAAaacgtttgtaaggTTATAAAATAAAACGTAATTat t" /listShort="rpmEB, ytiB, S1173, luxS, ytkA, S1172" /listLong="dps, S1171, ytkC, S1170, ytkD" /label="promotor_-35" upshifts complement(3004889) /Source="Nicolas_upshifts" /id="U2380" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.571428571428571" /psig="0.994005994005994" /xcortree=663 /SigmaFactorBS="cctattcttaaatgccatgaggtttacgatgtgaaacagagg gaaggatataagaagATTGACAAaacgtttgtaaggTTATAAAATAAAACGTAATTat t" /listShort="rpmEB, ytiB, S1173, luxS, ytkA, S1172" /listLong="dps, S1171, ytkC, S1170, ytkD" promotor_-35 3004951..3004957 /Source="Nicolas_upshift_promotors" /id="U2381" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=902 /SigmaFactorBS="gtaaacctcatggcatttaagaataggaAGAATAAtctaacc gaggaaGCAAATAATAAAcccaaaatacatacagaacgtctttttggaaaggtggttt a" /listShort="ythA, ythB" /listLong="ytzL" /label="promotor_-35" promotor_-10 3004971..3004982 /Source="Nicolas_upshift_promotors" /id="U2381" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=902 /SigmaFactorBS="gtaaacctcatggcatttaagaataggaAGAATAAtctaacc gaggaaGCAAATAATAAAcccaaaatacatacagaacgtctttttggaaaggtggttt a" /listShort="ythA, ythB" /listLong="ytzL" /label="promotor_-10" upshifts 3004983 /Source="Nicolas_upshifts" /id="U2381" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=902 /SigmaFactorBS="gtaaacctcatggcatttaagaataggaAGAATAAtctaacc gaggaaGCAAATAATAAAcccaaaatacatacagaacgtctttttggaaaggtggttt a" /listShort="ythA, ythB" /listLong="ytzL" CDS 3005029..3006360 /gene="ythA" /locus_tag="BSU_30710" /old_locus_tag="BSU30710" /EC_number="1.10.3.-" /function="16.10: Respire" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 9852001, 10551842, 15849754, 16850406, 17114254; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative cytochrome bd menaquinol oxidase subunit I" /protein_id="NP_390949.2" /db_xref="EnsemblGenomes-Gn:BSU30710" /db_xref="EnsemblGenomes-Tr:CAB15049" /db_xref="GOA:C0SP90" /db_xref="InterPro:IPR002585" /db_xref="SubtiList:BG13857" /db_xref="UniProtKB/Swiss-Prot:C0SP90" /translation="MDDLVLARSLFGTTMGFHIIFATLGVGLPLMILVAELIYQKTKD DHYAIMAKRWTKAQAVLLGVAIPTGTIAGTQLALLWPGFMEVIGRVMSLPFQIEIYAF FVEALFMSIYVYAADRLSPAMRIVAVFFVLVGAAASAVLITNVHAFEGTPAGFKILNG KITDVDPWAAFFNPSFFITAGHVVLSAFMTGAFIVASVAAYKMIRTRKKERVYRFHRK ALLLALTIGGIFSLLTALNGHESAQMLYEYQPEKLAGAEGLFETRSHAPLAIGGFTDP NEEKVKWAIEIPWALSFLAANRFDTVVKGLNAFPRDEWPPLFIHTLFNAMVGVGMLLI LYSIIGVVWRKVLKKDRFPTWLLIIFMTAGPFSLIGIEFGWIFACTGRQPWVIYHLLK TSDVVTTTGSIGVLFLFFTFVYAVLGAAVVYVLLYYFRKHPVDEDLNTAES*" gene 3005029..3006360 /gene="ythA" /locus_tag="BSU_30710" /old_locus_tag="BSU30710" CDS 3006404..3007444 /gene="ythB" /locus_tag="BSU_30720" /old_locus_tag="BSU30720" /EC_number="1.10.3.-" /function="16.10: Respire" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 11073895, 15576792, 15849754, 16850406, 10551842; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative cytochrome bd menaquinol oxidase subunit II" /protein_id="NP_390950.1" /db_xref="EnsemblGenomes-Gn:BSU30720" /db_xref="EnsemblGenomes-Tr:CAB15050" /db_xref="GOA:O34505" /db_xref="InterPro:IPR003317" /db_xref="SubtiList:BG13858" /db_xref="UniProtKB/Swiss-Prot:O34505" /translation="MEISTDALIAISIIWGFVFIYAVMATMDFGAGFWSMIYLNKEHM KATDIANRFLSPTWEVTNVFIVAIVVALFSFFPGATFVLGTVLLIPGSMILLLLAIRS GFLVFSNTAKERKTLRYISGISGFIIPAILILVLPVTHGGFIEKTDGIYNLNMSKIFS SPNAYSFIGFAILSTLFLSSLLLADFSNVAEEQDAYRAYRKSALITGPISLLFAVCIM VTMRNEANWLYSGMMNDFSWIIASFITFVIAGIALFLPNKSFGQNIGKPRLALVAIGI QYFLASYAYGRAHLPYMIYPDVTVMSGFTEPATFRALFATYIVAFIILFPGFFFFWKM FMRDKRYIRQEE*" gene 3006404..3007444 /gene="ythB" /locus_tag="BSU_30720" /old_locus_tag="BSU30720" promotor_-35 3007438..3007444 /Source="Nicolas_upshift_promotors" /id="U2382" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=831 /SigmaFactorBS="atgcgagataaacgctatatccgccaggaGGAATAGagggca agccagccGGCTATACTAATccagaacctttataaggaggggatggcatggagcagaa a" /listShort="ytzL" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3007459..3007470 /Source="Nicolas_upshift_promotors" /id="U2382" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=831 /SigmaFactorBS="atgcgagataaacgctatatccgccaggaGGAATAGagggca agccagccGGCTATACTAATccagaacctttataaggaggggatggcatggagcagaa a" /listShort="ytzL" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3007469 /Source="Nicolas_upshifts" /id="U2382" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=831 /SigmaFactorBS="atgcgagataaacgctatatccgccaggaGGAATAGagggca agccagccGGCTATACTAATccagaacctttataaggaggggatggcatggagcagaa a" /listShort="ytzL" /GFF_Attribute="listLong" CDS 3007498..3007656 /gene="ytzL" /locus_tag="BSU_30739" /old_locus_tag="BSU30739" /function="18: Unknown function" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 17322312" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="YP_003097775.1" /db_xref="EnsemblGenomes-Gn:BSU30739" /db_xref="EnsemblGenomes-Tr:CAX52681" /db_xref="InterPro:IPR011437" /db_xref="UniProtKB/Swiss-Prot:C0H3Q2" /translation="MEQKILCEVNNCSYWGKGNKCTADAIYVVSHTGETAENSRETDC KTFKPHDL*" gene 3007498..3007656 /gene="ytzL" /locus_tag="BSU_30739" /old_locus_tag="BSU30739" downshifts 3007645 /Source="Nicolas_upshifts" /id="D1584" /incds=0 /nref=55 /ntot=88 /MaxReadThrough="1.7679" /MaxDrop="7.01398" /score="-5.86934022" /energy="-7" /TU="NA" /idTUdmin="U2382" /TUdmin=0 /isTUend="TRUE" CDS complement(3007675..3008562) /gene="mntD" /locus_tag="BSU_30740" /old_locus_tag="BSU30740" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:49350, 15849754, 15948947, 16566604, 16704341, 16850406" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 49350, 15849754, 15948947, 16566604, 16704341, 16850406; Product type t : transporter" /codon_start=1 /transl_table=11 /product="manganese ABC transporter (permease)" /protein_id="NP_390952.1" /db_xref="EnsemblGenomes-Gn:BSU30740" /db_xref="EnsemblGenomes-Tr:CAB15052" /db_xref="GOA:O34500" /db_xref="InterPro:IPR001626" /db_xref="InterPro:IPR035568" /db_xref="SubtiList:BG13854" /db_xref="UniProtKB/Swiss-Prot:O34500" /translation="MSFEAWIIATGVLVGVSCGLIGTFLVLRSMAMLADAISHTVLLG IVGAFLVTGSLDGIYMFIGAAATGLLTAFLVQLLHSKGVQSDAAIGVVFTSLFAIGVI LLSVYGANVHLDIEHSLMGEIAFVPWNTVTVFGVDIGPKAFWMLASVLVLNVVLISVC YKEFKIASFDPQMALALGIPVLLIHYVQMGMLSLTTVASFDSVGAVLVVAMLIVPPAA AHLLTDRLLYMLILSALIGGLSAVMGYFFATWLNVSISGAMAAMTGVCYASAFLFSPA NGVITKKLRTLNMQKERAG*" gene complement(3007675..3008562) /gene="mntD" /locus_tag="BSU_30740" /old_locus_tag="BSU30740" downshifts complement(3007698) /Source="Nicolas_upshifts" /id="D1585" /incds=0 /nref=121 /ntot=218 /MaxReadThrough="3.39755" /MaxDrop="6.80546" /score="-8.37820006" /energy="-7" /TU="U2385" /idTUdmin="U2385" /TUdmin="-637" /isTUend="FALSE" CDS complement(3008552..3009859) /gene="mntC" /locus_tag="BSU_30750" /old_locus_tag="BSU30750" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:49350, 15849754, 15948947, 16566604, 16704341, 16850406" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 49350, 15849754, 15948947, 16566604, 16704341, 16850406; Product type t : transporter" /codon_start=1 /transl_table=11 /product="manganese ABC transporter (permease)" /protein_id="NP_390953.1" /db_xref="EnsemblGenomes-Gn:BSU30750" /db_xref="EnsemblGenomes-Tr:CAB15053" /db_xref="GOA:O35024" /db_xref="InterPro:IPR001626" /db_xref="InterPro:IPR035568" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG13853" /db_xref="UniProtKB/Swiss-Prot:O35024" /translation="MFESLWLQLQHPNTQWVLAGTLLLGTASGVLGSFVLLRKQSLIG DAMAHSALPGVCLAFLFTGQKSLPFFLLGAALAGLLGTFCIQLIPRLSKTKEDSAIGI VLSVFFGVGIILLTYIQQQGAGSQSGLDSFLFGQAASLVRQDIILIAGISAVLLLLCI VFFKEFTLITFDLAFAKGLGIPVRFLNGLLACLIVCAVVIGLQTVGVILMAAMLITPA ITARYWTERLTGMIIIAGITGGVSGVAGTLLSTTMKGMATGPLMILSATLLFLFSMIC APKRGLAAKAIRLMRLRRRTSREQVLLAIYEQYEKNNLCVTVESVRKKRRLSPSLCLK ALNDLEQERCIERIENGIWQITSKGIEKGYHTALKQRMYEVYLMHEMELANIESDQDY FDPDRLPRETRERLYSLLKLYGRMPERRKASHDAEKGQIANEF*" gene complement(3008552..3009859) /gene="mntC" /locus_tag="BSU_30750" /old_locus_tag="BSU30750" CDS complement(3009865..3010617) /gene="mntB" /locus_tag="BSU_30760" /old_locus_tag="BSU30760" /EC_number="3.6.3.-" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:10760146, 15948947, 16566604, 16704341" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10760146, 15948947, 16566604, 16704341; Product type t: transporter" /codon_start=1 /transl_table=11 /product="manganese ABC transporter (ATP-binding protein)" /protein_id="NP_390954.1" /db_xref="EnsemblGenomes-Gn:BSU30760" /db_xref="EnsemblGenomes-Tr:CAB15054" /db_xref="GOA:O34338" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR017871" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG13852" /db_xref="UniProtKB/Swiss-Prot:O34338" /translation="MFPVELDNVTVAYHKKPVLQDISLQVPEGKLIGIIGPNGAGKST LIKTILGLVPRASGDISIYGKDYKDQRTRIGYVPQRGSVDWDFPTSPLDVVLMGRYGR IGLLKRPKKADVEMAKAALTKVGMHDYAKRQISQLSGGQQQRVFLARALCQNADIYFM DEPFAGVDAATERAIMTLLAELKEKGKTVLVVHHDLQTAEDYFDWILLLHLRKIAFGP TENVFTIENLQKTYGGRLTFLKDKVLAEGHKE*" gene complement(3009865..3010617) /gene="mntB" /locus_tag="BSU_30760" /old_locus_tag="BSU30760" CDS complement(3010636..3011556) /gene="mntA" /locus_tag="BSU_30770" /old_locus_tag="BSU30770" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:10760146, 15948947, 16566604, 16704341" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10760146, 15948947, 16566604, 16704341; Product type lp: lipoprotein" /codon_start=1 /transl_table=11 /product="manganese ABC transporter (manganese binding lipoprotein)" /protein_id="NP_390955.1" /db_xref="EnsemblGenomes-Gn:BSU30770" /db_xref="EnsemblGenomes-Tr:CAB15055" /db_xref="GOA:O34385" /db_xref="InterPro:IPR006127" /db_xref="InterPro:IPR006128" /db_xref="InterPro:IPR006129" /db_xref="SubtiList:BG13851" /db_xref="UniProtKB/Swiss-Prot:O34385" /translation="MRQGLMAAVLFATFALTGCGTDSAGKSADQQLQVTATTSQIADA AENIGGKHVKVTSLMGPGVDPHLYKASQGDTKKLMSADVVLYSGLHLEGKMEDVLQKI GEQKQSAAVAEAIPKNKLIPAGEGKTFDPHVWFSIPLWIYAVDEIEAQFSKAMPQHAD AFRKNAKEYKEDLQYLDKWSRKEIAHIPEKSRVLVTAHDAFAYFGNEYGFKVKGLQGL STDSDYGLRDVQELVDLLTEKQIKAVFVESSVSEKSINAVVEGAKEKGHTVTIGGQLY SDAMGEKGTKEGTYEGMFRHNINTITKALK*" gene complement(3010636..3011556) /gene="mntA" /locus_tag="BSU_30770" /old_locus_tag="BSU30770" promotor_-10 complement(3011592..3011603) /Source="Nicolas_upshift_promotors" /id="U2383" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.52047952047952" /psig="0.52047952047952" /xcortree=407 /SigmaFactorBS="aataaaacatgcttttggctaatttaatgtCACATGTctaag aactgacaACATAAGATAAAacaatcggacattgatggcaaagaggaggagaaatatg a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3011593) /Source="Nicolas_upshifts" /id="U2383" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.52047952047952" /psig="0.52047952047952" /xcortree=407 /SigmaFactorBS="aataaaacatgcttttggctaatttaatgtCACATGTctaag aactgacaACATAAGATAAAacaatcggacattgatggcaaagaggaggagaaatatg a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" S_feature complement(3011595..3011686) /Source="Nicolas_S_feature" /locus_tag="new_3145997_3146088_c" /HighExp="T-0.40H, Sw, T-1.40H, BC, C90, C30, BI, T0.0H, T-3.40H, T-1.10H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="0.985, 0.982" /TUlongSig="NA" /TUlongPSig="NA" /label="S1174" promotor_-35 complement(3011617..3011623) /Source="Nicolas_upshift_promotors" /id="U2383" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.52047952047952" /psig="0.52047952047952" /xcortree=407 /SigmaFactorBS="aataaaacatgcttttggctaatttaatgtCACATGTctaag aactgacaACATAAGATAAAacaatcggacattgatggcaaagaggaggagaaatatg a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 3011671 /Source="Nicolas_upshifts" /id="U2384" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.649350649350649" /psig="0.0549450549450549" /xcortree=296 /SigmaFactorBS="tcttagacatgtgacattaaattagccaaaagcatgttttat ttacacaggacaaaaagtttcCCTCATGCAAAATtatcgcgtttggccatttttgtca a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 complement(3011672..3011691) /Source="Nicolas_upshift_promotors" /id="U2385" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.596403596403596" /psig="0.985014985014985" /xcortree=1526 /SigmaFactorBS="ctgctgacccagccggtttttttatgtaaatcaGCTTGACAa aaatggccaaacgCGATAATTTTGCATGAGGGAaactttttgtcctgtgtaaataaaa c" /listShort="S1174, mntA, mntB, mntC, mntD" /GFF_Attribute="listLong" /label="promotor_-10" misc_feature 3011674..3011686 /Source="Nicolas_upshift_promotors" /id="U2384" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.649350649350649" /psig="0.0549450549450549" /xcortree=296 /SigmaFactorBS="tcttagacatgtgacattaaattagccaaaagcatgttttat ttacacaggacaaaaagtttcCCTCATGCAAAATtatcgcgtttggccatttttgtca a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(3011686) /Source="Nicolas_upshifts" /id="U2385" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.596403596403596" /psig="0.985014985014985" /xcortree=1526 /SigmaFactorBS="ctgctgacccagccggtttttttatgtaaatcaGCTTGACAa aaatggccaaacgCGATAATTTTGCATGAGGGAaactttttgtcctgtgtaaataaaa c" /listShort="S1174, mntA, mntB, mntC, mntD" /GFF_Attribute="listLong" S_feature complement(3011688..3011769) /Source="Nicolas_S_feature" /locus_tag="new_3146090_3146171_c" /HighExp="T1.30H, T1.0H, C30, T0.30H, T2.0H, T2.30H, T-0.40H, T-1.40H, T-2.40H, GM 150" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.982" /TUlongSig="NA" /TUlongPSig="NA" /label="S1175" promotor_-35 complement(3011706..3011713) /Source="Nicolas_upshift_promotors" /id="U2385" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.596403596403596" /psig="0.985014985014985" /xcortree=1526 /SigmaFactorBS="ctgctgacccagccggtttttttatgtaaatcaGCTTGACAa aaatggccaaacgCGATAATTTTGCATGAGGGAaactttttgtcctgtgtaaataaaa c" /listShort="S1174, mntA, mntB, mntC, mntD" /GFF_Attribute="listLong" /label="promotor_-35" upshifts complement(3011769) /Source="Nicolas_upshifts" /id="U2386" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.837162837162837" /psig="0.982017982017982" /xcortree=2960 /SigmaFactorBS="agcattttgctATTTTGAAtaaatgacactgtGCTGTTACAG TAAAAGTGTTcgttgaatacatcccttctcgtttggaccggctgctgacccagccggt t" /listShort="S1175, S1174, mntA, mntB, mntC" /listLong="mntD" promotor_-10 complement(3011778..3011797) /Source="Nicolas_upshift_promotors" /id="U2386" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.837162837162837" /psig="0.982017982017982" /xcortree=2960 /SigmaFactorBS="agcattttgctATTTTGAAtaaatgacactgtGCTGTTACAG TAAAAGTGTTcgttgaatacatcccttctcgtttggaccggctgctgacccagccggt t" /listShort="S1175, S1174, mntA, mntB, mntC" /listLong="mntD" /label="promotor_-10" promotor_-35 complement(3011811..3011818) /Source="Nicolas_upshift_promotors" /id="U2386" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.837162837162837" /psig="0.982017982017982" /xcortree=2960 /SigmaFactorBS="agcattttgctATTTTGAAtaaatgacactgtGCTGTTACAG TAAAAGTGTTcgttgaatacatcccttctcgtttggaccggctgctgacccagccggt t" /listShort="S1175, S1174, mntA, mntB, mntC" /listLong="mntD" /label="promotor_-35" CDS complement(3011836..3012951) /gene="menC" /locus_tag="BSU_30780" /old_locus_tag="BSU30780" /EC_number="4.2.1.113" /function="16.2: Construct biomass (Anabolism)" /function="16.10: Respire" /experiment="publication(s) with functional evidences, PMID:6780514, 8566759, 9139683, 12682299" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 6780514, 8566759, 9139683, 12682299; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="O-succinylbenzoate-CoA synthase" /protein_id="NP_390956.1" /db_xref="EnsemblGenomes-Gn:BSU30780" /db_xref="EnsemblGenomes-Tr:CAB15056" /db_xref="GOA:O34514" /db_xref="InterPro:IPR010197" /db_xref="InterPro:IPR013341" /db_xref="InterPro:IPR013342" /db_xref="InterPro:IPR029017" /db_xref="InterPro:IPR029065" /db_xref="InterPro:IPR034390" /db_xref="InterPro:IPR036849" /db_xref="SubtiList:BG13847" /db_xref="UniProtKB/Swiss-Prot:O34514" /translation="MIEIEKITLYHLSMNLKKPFKNSIETLQERKFLIVEAIDTSGVT GWGEVSAFSSPWYTEETIGTCLHMLKDFFIPNVVGREFNHPSEVPDSLARYKGNRMAK AGLESAVWDIYAKKKGVSLAEALGGTRDKVPAGVVVGLAPLDDMLKEIESYQKEGYQR IKIKIQPGQDVELVKAIRSRFPTIPLMADANSSYELKDISRLKELDDYHLMMIEQPLQ ADDIVDHRHLQKHLKTAICLDESICSVDDARRAIELGSCKIINIKPSRVGGLTEALKI HDLCKEHHMQVWCGGMLETGISRAQNVALASLPQFTIPGDISSSSRYWDEDIVTPDIR IDNGFISVSKQPGLGVEVNQDIMRKYVTKMDVFTQHG*" gene complement(3011836..3012951) /gene="menC" /locus_tag="BSU_30780" /old_locus_tag="BSU30780" downshifts complement(3011879) /Source="Nicolas_upshifts" /id="D1586" /incds=0 /nref=12 /ntot=179 /MaxReadThrough="3.8638" /MaxDrop="2.96378" /score="29.7201414" /energy="-11.1" /TU="U2387,U2388" /idTUdmin="U2388" /TUdmin="-22" /isTUend="TRUE" CDS complement(3012948..3014408) /gene="menE" /locus_tag="BSU_30790" /old_locus_tag="BSU30790" /EC_number="6.2.1.26" /function="16.10: Respire" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:6780514, 6780515, 8566759, 9139683, 12682299, 28559280" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 6780514, 6780515, 8566759, 9139683, 12682299, 28559280; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="O-succinylbenzoic acid-CoA ligase" /protein_id="NP_390957.1" /db_xref="EnsemblGenomes-Gn:BSU30790" /db_xref="EnsemblGenomes-Tr:CAB15057" /db_xref="GOA:P23971" /db_xref="InterPro:IPR000873" /db_xref="InterPro:IPR010192" /db_xref="InterPro:IPR020845" /db_xref="InterPro:IPR025110" /db_xref="PDB:5BUQ" /db_xref="PDB:5BUR" /db_xref="PDB:5BUS" /db_xref="PDB:5GTD" /db_xref="PDB:5X8F" /db_xref="PDB:5X8G" /db_xref="SubtiList:BG10687" /db_xref="UniProtKB/Swiss-Prot:P23971" /translation="MLTEQPNWLMQRAQLTPERIALIYEDQTVTFAELFAASKRMAEQ LAAHSVRKGDTAAILLQNRAEMVYAVHACFLLGVKAVLLNTKLSTHERLFQLEDSGSG FLLTDSSFEKKEYEHIVQTIDVDELMKEAAEEIEIEAYMQMDATATLMYTSGTTGKPK GVQQTFGNHYFSAVSSALNLGITEQDRWLIALPLFHISGLSALFKSVIYGMTVVLHQR FSVSDVLHSINRHEVTMISAVQTMLASLLEETNRCPESIRCILLGGGPAPLPLLEECR EKGFPVFQSYGMTETCSQIVTLSPEFSMEKLGSAGKPLFSCEIKIERDGQVCEPYEHG EIMVKGPNVMKSYFNRESANEASFQNGWLKTGDLGYLDNEGFLYVLDRRSDLIISGGE NIYPAEVESVLLSHPAVAEAGVSGAEDKKWGKVPHAYLVLHKPVSAGELTDYCKERLA KYKIPAKFFVLDRLPRNASNKLLRNQLKDARKGELL*" gene complement(3012948..3014408) /gene="menE" /locus_tag="BSU_30790" /old_locus_tag="BSU30790" promotor_-10 complement(3013851..3013869) /Source="Nicolas_upshift_promotors" /id="U2387" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=257 /SigmaFactorBS="cgttcggaaaccattatttcagtgcGGTGTCGtccgctctta atttGGGTATAACAGAACAAGACcgctggcttatcgcattgccgctctttcatatcag c" /listShort="menC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3013855) /Source="Nicolas_upshifts" /id="U2387" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=257 /SigmaFactorBS="cgttcggaaaccattatttcagtgcGGTGTCGtccgctctta atttGGGTATAACAGAACAAGACcgctggcttatcgcattgccgctctttcatatcag c" /listShort="menC" /GFF_Attribute="listLong" promotor_-35 complement(3013884..3013890) /Source="Nicolas_upshift_promotors" /id="U2387" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=257 /SigmaFactorBS="cgttcggaaaccattatttcagtgcGGTGTCGtccgctctta atttGGGTATAACAGAACAAGACcgctggcttatcgcattgccgctctttcatatcag c" /listShort="menC" /GFF_Attribute="listLong" /label="promotor_-35" downshifts complement(3014497) /Source="Nicolas_upshifts" /id="D1587" /incds=0 /nref=1 /ntot=97 /MaxReadThrough="4.92536" /MaxDrop="2.4145" /score="1.01127104" /energy="-10.8" /TU="U2388" /idTUdmin="U2389" /TUdmin=682 /isTUend="FALSE" CDS complement(3014499..3015314) /gene="menB" /locus_tag="BSU_30800" /old_locus_tag="BSU30800" /EC_number="4.1.3.36" /function="16.2: Construct biomass (Anabolism)" /function="16.10: Respire" /experiment="publication(s) with functional evidences, PMID:6780514, 6780515, 8566759, 9139683, 12682299" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 6780514, 6780515, 8566759, 9139683, 12682299; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="dihydroxynapthoic acid synthetase" /protein_id="NP_390958.1" /db_xref="EnsemblGenomes-Gn:BSU30800" /db_xref="EnsemblGenomes-Tr:CAB15058" /db_xref="GOA:P23966" /db_xref="InterPro:IPR001753" /db_xref="InterPro:IPR010198" /db_xref="InterPro:IPR014748" /db_xref="InterPro:IPR018376" /db_xref="InterPro:IPR029045" /db_xref="SubtiList:BG10686" /db_xref="UniProtKB/Swiss-Prot:P23966" /translation="MAEWKTKRTYDEILYETYNGIAKITINRPEVHNAFTPKTVAEMI DAFADARDDQNVGVIVLAGAGDKAFCSGGDQKVRGHGGYVGDDQIPRLNVLDLQRLIR VIPKPVVAMVSGYAIGGGHVLHIVCDLTIAADNAIFGQTGPKVGSFDAGYGSGYLARI VGHKKAREIWYLCRQYNAQEALDMGLVNTVVPLEQLEEETIKWCEEMLEKSPTALRFL KAAFNADTDGLAGIQQFAGDATLLYYTTDEAKEGRDSFKEKRKPDFGQFPRFP*" gene complement(3014499..3015314) /gene="menB" /locus_tag="BSU_30800" /old_locus_tag="BSU30800" CDS complement(3015349..3016173) /gene="menH" /locus_tag="BSU_30810" /old_locus_tag="BSU30810" /EC_number="4.2.99.20" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 12454479, 23637813; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase" /protein_id="NP_390959.1" /db_xref="EnsemblGenomes-Gn:BSU30810" /db_xref="EnsemblGenomes-Tr:CAB15059" /db_xref="GOA:P23974" /db_xref="InterPro:IPR000073" /db_xref="InterPro:IPR000639" /db_xref="InterPro:IPR022485" /db_xref="InterPro:IPR029058" /db_xref="SubtiList:BG10685" /db_xref="UniProtKB/Swiss-Prot:P23974" /translation="MGTVNITVSDGVRYAVADEGPNASEAVVCLHGFTGSKQSWTFLD EMLPDSRLIKIDCLGHGETDAPLNGKRYSTTRQVSDLAEIFDQLKLHKVKLIGYSMGG RLAYSFAMTYPERVSALVLESTTPGLKTLGERRERIMRDRKLADFILRDGLEAFVAYW ENIPLFSSQQRLAEDIRYRIRSGRLRNNKIGLANSLTGMGTGSQPSLWSRVEEIDVPV LLICGEWDEKFCAINQEVHKMLPSSRIEIVPKAGHTVHVEQPRLFGKIVSEFLTSI*" gene complement(3015349..3016173) /gene="menH" /locus_tag="BSU_30810" /old_locus_tag="BSU30810" promotor_-10 complement(3015431..3015450) /Source="Nicolas_upshift_promotors" /id="U2388" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.534465534465534" /psig="0.993006993006993" /xcortree=2696 /SigmaFactorBS="aattttgcgccatcaatcaagaGGTGcataagatgcttcctT CTAGTAGAATAGAGATTGTtccaaaagcaggacatacggtccatgtggagcagccgcg a" /listShort="menB, menE, menC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3015431) /Source="Nicolas_upshifts" /id="U2388" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.534465534465534" /psig="0.993006993006993" /xcortree=2696 /SigmaFactorBS="aattttgcgccatcaatcaagaGGTGcataagatgcttcctT CTAGTAGAATAGAGATTGTtccaaaagcaggacatacggtccatgtggagcagccgcg a" /listShort="menB, menE, menC" /GFF_Attribute="listLong" promotor_-35 complement(3015466..3015469) /Source="Nicolas_upshift_promotors" /id="U2388" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.534465534465534" /psig="0.993006993006993" /xcortree=2696 /SigmaFactorBS="aattttgcgccatcaatcaagaGGTGcataagatgcttcctT CTAGTAGAATAGAGATTGTtccaaaagcaggacatacggtccatgtggagcagccgcg a" /listShort="menB, menE, menC" /GFF_Attribute="listLong" /label="promotor_-35" upshifts complement(3015597) /Source="Nicolas_upshifts" /id="U2389" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.706293706293706" /psig="0.706293706293706" /xcortree=1445 /SigmaFactorBS="gctgaagatattcggtacAGGATACgatcgggccgtctgCGG AACAATAAGattgggcttgcgaacagtttaaccggcatgggcaccggttcacagcctt c" /listShort="menB" /GFF_Attribute="listLong" promotor_-10 complement(3015607..3015618) /Source="Nicolas_upshift_promotors" /id="U2389" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.706293706293706" /psig="0.706293706293706" /xcortree=1445 /SigmaFactorBS="gctgaagatattcggtacAGGATACgatcgggccgtctgCGG AACAATAAGattgggcttgcgaacagtttaaccggcatgggcaccggttcacagcctt c" /listShort="menB" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 complement(3015633..3015639) /Source="Nicolas_upshift_promotors" /id="U2389" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.706293706293706" /psig="0.706293706293706" /xcortree=1445 /SigmaFactorBS="gctgaagatattcggtacAGGATACgatcgggccgtctgCGG AACAATAAGattgggcttgcgaacagtttaaccggcatgggcaccggttcacagcctt c" /listShort="menB" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3016161..3017903) /gene="menD" /locus_tag="BSU_30820" /old_locus_tag="BSU30820" /EC_number="2.2.1.9" /function="16.2: Construct biomass (Anabolism)" /function="16.10: Respire" /experiment="publication(s) with functional evidences, PMID:6780514, 8169214, 8566759, 12682299" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 6780514, 8169214, 8566759, 12682299; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="2-oxoglutarate decarboxylase and 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1- carboxylic-acid synthase" /protein_id="NP_390960.1" /db_xref="EnsemblGenomes-Gn:BSU30820" /db_xref="EnsemblGenomes-Tr:CAB15060" /db_xref="GOA:P23970" /db_xref="InterPro:IPR004433" /db_xref="InterPro:IPR011766" /db_xref="InterPro:IPR012001" /db_xref="InterPro:IPR029035" /db_xref="InterPro:IPR029061" /db_xref="InterPro:IPR032264" /db_xref="PDB:2X7J" /db_xref="SubtiList:BG10683" /db_xref="UniProtKB/Swiss-Prot:P23970" /translation="MTVNPITHYIGSFIDEFALSGITDAVVCPGSRSTPLAVLCAAHP DISVHVQIDERSAGFFALGLAKAKQRPVLLICTSGTAAANFYPAVVEAHYSRVPIIVL TADRPHELREVGAPQAINQHFLFGNFVKFFTDSALPEESPQMLRYIRTLASRAAGEAQ KRPMGPVHVNVPLREPLMPDLSDEPFGRMRTGRHVSVKTGTQSVDRESLSDVAEMLAE AEKGMIVCGELHSDADKENIIALSKALQYPILADPLSNLRNGVHDKSTVIDAYDSFLK DDELKRKLRPDVVIRFGPMPVSKPVFLWLKDDPTIQQIVIDEDGGWRDPTQASAHMIH CNASVFAEEIMAGLTAATRSSEWLEKWQFVNGRFREHLQTISSEDVSFEGNLYRILQH LVPENSSLFVGNSMPIRDVDTFFEKQDRPFRIYSNRGANGIDGVVSSAMGVCEGTKAP VTLVIGDLSFYHDLNGLLAAKKLGIPLTVILVNNDGGGIFSFLPQASEKTHFEDLFGT PTGLDFKHAAALYGGTYSCPASWDEFKTAYAPQADKPGLHLIEIKTDRQSRVQLHRDM LNEAVREVKKQWEL*" gene complement(3016161..3017903) /gene="menD" /locus_tag="BSU_30820" /old_locus_tag="BSU30820" CDS complement(3017900..3019315) /gene="menF" /locus_tag="BSU_30830" /old_locus_tag="BSU30830" /EC_number="5.4.4.2" /function="16.10: Respire" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:6780514, 8169214, 8566759" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 6780514, 8169214, 8566759; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="menaquinone-specific isochorismate synthase" /protein_id="NP_390961.1" /db_xref="EnsemblGenomes-Gn:BSU30830" /db_xref="EnsemblGenomes-Tr:CAB15061" /db_xref="GOA:P23973" /db_xref="InterPro:IPR004561" /db_xref="InterPro:IPR005801" /db_xref="InterPro:IPR015890" /db_xref="InterPro:IPR034681" /db_xref="SubtiList:BG10682" /db_xref="UniProtKB/Swiss-Prot:P23973" /translation="MVTTVQRTFRKEVLHALHKAKEVNHAVLISYSRQIESLDPLSFF NYGAKKYTGNRFFWSDPESELTIVGLGKEAVFQTNQKNSERYREVFEQWERFKKTAFH IYEEEKLQHSAVGPVLFGGFSFDPCEERGSQWDHFSEGDFFVPALMLTMTAEGPFLTV NRWVSGGEDAEAVLEGLKAFAAEFMVPDFKQEDQAVIAAAEELDKDDWLKAIETATSQ IKEKQYDKVVLARELLLTFDGPIQIEPVLKTLLDDQQTSYVFAIEQEGKTFVGASPER LIKRDGGTVMSSCLAGSIKRGVNEEDDRRIGLELLNDEKNLLEHDIVVGMIHNAFVSS CSEVEKPDGPVLYKTKSVQHLFTPIVGQLRESASIFDLIEKLHPTPALGGSPQEKAVD VIREIEPMSRGWYAAPIGWIDSQDNGEFAVAIRSGLIEGSTARLFAGCGIVEDSEPIS EYEETQIKLKPMISALGGERR*" gene complement(3017900..3019315) /gene="menF" /locus_tag="BSU_30830" /old_locus_tag="BSU30830" S_feature complement(3019316..3019428) /Source="Nicolas_S_feature" /locus_tag="new_3153718_3153830_c" /HighExp="dia5, LBGstat, Diami, LBGtran, dia15, H2O2, G180, G150, LPhT, G135" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigK" /TUshortPSig="1, 0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S1176" promotor_-10 complement(3019408..3019427) /Source="Nicolas_upshift_promotors" /id="U2390" /multdbtbs="SigA" /comp="M16" /sig="SigA" /pcomp="0.721278721278721" /psig=1 /xcortree=1834 /SigmaFactorBS="caacctttgctatcagtggagaaagaaatttaagctttgttt CTTTttcatttctgaaattAGGTTTATAATAGGTAAGGCaggccatttggactgcatg a" /listShort="S1176, menF, menD, ytxM" /listLong="menB, menE, menC" /label="promotor_-10" upshifts complement(3019428) /Source="Nicolas_upshifts" /id="U2390" /multdbtbs="SigA" /comp="M16" /sig="SigA" /pcomp="0.721278721278721" /psig=1 /xcortree=1834 /SigmaFactorBS="caacctttgctatcagtggagaaagaaatttaagctttgttt CTTTttcatttctgaaattAGGTTTATAATAGGTAAGGCaggccatttggactgcatg a" /listShort="S1176, menF, menD, ytxM" /listLong="menB, menE, menC" S_feature complement(3019430..3019580) /Source="Nicolas_S_feature" /locus_tag="new_3153832_3153982_c" /HighExp="S8, S7, S6, S5, BT, S4, Pyr, B36, G/S, S3" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigK" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S1177" promotor_-35 complement(3019443..3019446) /Source="Nicolas_upshift_promotors" /id="U2390" /multdbtbs="SigA" /comp="M16" /sig="SigA" /pcomp="0.721278721278721" /psig=1 /xcortree=1834 /SigmaFactorBS="caacctttgctatcagtggagaaagaaatttaagctttgttt CTTTttcatttctgaaattAGGTTTATAATAGGTAAGGCaggccatttggactgcatg a" /listShort="S1176, menF, menD, ytxM" /listLong="menB, menE, menC" /label="promotor_-35" promotor_-35 3019541..3019547 /Source="Nicolas_upshift_promotors" /id="U2391" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp="0.984015984015984" /psig="0.984015984015984" /xcortree=863 /SigmaFactorBS="aaaacctcctatattcctccacccgccatttaTGAAAGTtct caggcgatctGTTCATACTAAAggtatgcatcacagagaaacgaggcgatcacattgc t" /listShort="yteA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(3019561..3019580) /Source="Nicolas_upshift_promotors" /id="U2392" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1266 /SigmaFactorBS="attttttaaatgctgaagctgttctttcgtaagcaatGTGAT CGCCTcgtttctctgtgaTGCATACCTTTAGTATGAACagatcgcctgagaactttca t" /listShort="S1177, S1176, menF" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-10 3019561..3019572 /Source="Nicolas_upshift_promotors" /id="U2391" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp="0.984015984015984" /psig="0.984015984015984" /xcortree=863 /SigmaFactorBS="aaaacctcctatattcctccacccgccatttaTGAAAGTtct caggcgatctGTTCATACTAAAggtatgcatcacagagaaacgaggcgatcacattgc t" /listShort="yteA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3019569 /Source="Nicolas_upshifts" /id="U2391" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp="0.984015984015984" /psig="0.984015984015984" /xcortree=863 /SigmaFactorBS="aaaacctcctatattcctccacccgccatttaTGAAAGTtct caggcgatctGTTCATACTAAAggtatgcatcacagagaaacgaggcgatcacattgc t" /listShort="yteA" /GFF_Attribute="listLong" upshifts complement(3019580) /Source="Nicolas_upshifts" /id="U2392" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1266 /SigmaFactorBS="attttttaaatgctgaagctgttctttcgtaagcaatGTGAT CGCCTcgtttctctgtgaTGCATACCTTTAGTATGAACagatcgcctgagaactttca t" /listShort="S1177, S1176, menF" /GFF_Attribute="listLong" promotor_-35 complement(3019594..3019603) /Source="Nicolas_upshift_promotors" /id="U2392" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1266 /SigmaFactorBS="attttttaaatgctgaagctgttctttcgtaagcaatGTGAT CGCCTcgtttctctgtgaTGCATACCTTTAGTATGAACagatcgcctgagaactttca t" /listShort="S1177, S1176, menF" /GFF_Attribute="listLong" /label="promotor_-35" CDS 3019605..3020324 /gene="yteA" /locus_tag="BSU_30840" /old_locus_tag="BSU30840" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15496987; Product type f: factor" /codon_start=1 /transl_table=11 /product="putative regulatory protein" /protein_id="NP_390962.2" /db_xref="EnsemblGenomes-Gn:BSU30840" /db_xref="EnsemblGenomes-Tr:CAB15062" /db_xref="GOA:P42408" /db_xref="InterPro:IPR000962" /db_xref="InterPro:IPR014240" /db_xref="InterPro:IPR037187" /db_xref="SubtiList:BG11200" /db_xref="UniProtKB/Swiss-Prot:P42408" /translation="MLTKEQLQHLKNELEQTKKDILNRFKDNDHFQLNSAFPYDSWGE LSAYDNHPGDQATELYEREKDIALDLHEREHLRDIEHSLKAIENGTYGICEVSGKEIP FERLEALPTATTLAEYSSQDVVSKDRPIEEETPFGQFEFDDDEEIRAPYDSEDSYQDV EKYGNSQTPQDMENPPLSYDDMTMNAEENIGNTESYENFIATDITGKEITVYQSRAHE RYEEELDEEGIMTTFGDLHAD*" gene 3019605..3020324 /gene="yteA" /locus_tag="BSU_30840" /old_locus_tag="BSU30840" S_feature complement(3019675..3020332) /Source="Nicolas_S_feature" /locus_tag="new_3154077_3154734_c" /HighExp="S8, S6, S7, BT, B36, S5, S4, G/S, Pyr, S3" /AntisenseName="yteA" /AntisenseCor="0.85796245341056299" /AntisenseRegPval="-78.5" /CDS_PredictionProba="NA" /TUshortSig="SigK" /TUshortPSig="0.998" /TUlongSig="NA" /TUlongPSig="NA" /label="S1178" downshifts 3020313 /Source="Nicolas_upshifts" /id="D1588" /incds=0 /nref=23 /ntot=40 /MaxReadThrough="0.72949" /MaxDrop="5.85132" /score="2.75726503" /energy="-10.1" /TU="NA" /idTUdmin="U2391" /TUdmin="-5" /isTUend="TRUE" CDS complement(3020333..3021151) /gene="ytdA" /locus_tag="BSU_30850" /old_locus_tag="BSU30850" /EC_number="2.7.7.9" /function="16.8: Protect" /function="16.14: Store" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative UTP-glucose-1-phosphate uridylyltransferase" /protein_id="NP_390963.1" /db_xref="EnsemblGenomes-Gn:BSU30850" /db_xref="EnsemblGenomes-Tr:CAB15063" /db_xref="GOA:P42407" /db_xref="InterPro:IPR005835" /db_xref="InterPro:IPR029044" /db_xref="SubtiList:BG11199" /db_xref="UniProtKB/Swiss-Prot:P42407" /translation="MIKKAIIPAGGFGTRNLPVTKVIPKEMFPVGSKPVIHYLVEELK ESGIEDILMVVSSHKNLIVDYFDSSLALEAFLASKNKLHLLREHPIPDIRIHYVRQPY AKGLGDAISFGKQFAGGEPFAVVLPDDLIFSANQPALGQLIEAYTKYQSSVIGLKETK TEDLHHYGVIKGEPVEKGLYRIQDIVEKPKQNPPSHFAAAGRYIFTPDIFNELEALEA DSGGEVQVTDAIKASLGACTVYGKLLEGERYDIGLQKDYLKLIYDMLKTEKNPQ*" gene complement(3020333..3021151) /gene="ytdA" /locus_tag="BSU_30850" /old_locus_tag="BSU30850" promotor_-10 complement(3021172..3021191) /Source="Nicolas_upshift_promotors" /id="U2393" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=1317 /SigmaFactorBS="tctgcccagttgcttccgcctaatttcagatgTACAAACATc gggatgcgctcttGGAATATCATGTAATAAACAtgagctgaggggaaaataccatgat a" /listShort="ytdA, S1178" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3021186) /Source="Nicolas_upshifts" /id="U2393" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=1317 /SigmaFactorBS="tctgcccagttgcttccgcctaatttcagatgTACAAACATc gggatgcgctcttGGAATATCATGTAATAAACAtgagctgaggggaaaataccatgat a" /listShort="ytdA, S1178" /GFF_Attribute="listLong" promotor_-35 complement(3021206..3021214) /Source="Nicolas_upshift_promotors" /id="U2393" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=1317 /SigmaFactorBS="tctgcccagttgcttccgcctaatttcagatgTACAAACATc gggatgcgctcttGGAATATCATGTAATAAACAtgagctgaggggaaaataccatgat a" /listShort="ytdA, S1178" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 3021252..3021260 /Source="Nicolas_upshift_promotors" /id="U2394" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.99000999000999" /psig="0.99000999000999" /xcortree=1301 /SigmaFactorBS="acatctgaaattaggcggaagcaactgggcagaaagcgGAAT CACGAaccagcccttttTTAATAGGATATTGATATATgaccagtaatcttgtaaagga g" /listShort="ytcA, ytcB, ytcC, S1179" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3021273..3021292 /Source="Nicolas_upshift_promotors" /id="U2394" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.99000999000999" /psig="0.99000999000999" /xcortree=1301 /SigmaFactorBS="acatctgaaattaggcggaagcaactgggcagaaagcgGAAT CACGAaccagcccttttTTAATAGGATATTGATATATgaccagtaatcttgtaaagga g" /listShort="ytcA, ytcB, ytcC, S1179" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3021274 /Source="Nicolas_upshifts" /id="U2394" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.99000999000999" /psig="0.99000999000999" /xcortree=1301 /SigmaFactorBS="acatctgaaattaggcggaagcaactgggcagaaagcgGAAT CACGAaccagcccttttTTAATAGGATATTGATATATgaccagtaatcttgtaaagga g" /listShort="ytcA, ytcB, ytcC, S1179" /GFF_Attribute="listLong" CDS 3021323..3022609 /gene="ytcA" /locus_tag="BSU_30860" /old_locus_tag="BSU30860" /EC_number="1.1.1.22" /function="16.14: Store" /function="16.8: Protect" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative UDP-glucose dehydrogenase" /protein_id="NP_390964.1" /db_xref="EnsemblGenomes-Gn:BSU30860" /db_xref="EnsemblGenomes-Tr:CAB15064" /db_xref="GOA:O34862" /db_xref="InterPro:IPR001732" /db_xref="InterPro:IPR008927" /db_xref="InterPro:IPR014026" /db_xref="InterPro:IPR014027" /db_xref="InterPro:IPR017476" /db_xref="InterPro:IPR028357" /db_xref="InterPro:IPR036220" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG13828" /db_xref="UniProtKB/Swiss-Prot:O34862" /translation="MKICVVGAGYVGLTLSAALASIGHDMICTDKDVKKIGQLKKGVI PFYEPGLSDAILRCGNLSFSSEVKSSMEECPVIFIAVGTPPRSDGSADTKALQSVIGD LSEAIRSYKTIITKSTVPPGTNENIAKQLIASGVSKNLFNIVSNPEFLREGNALYDML HPDKTVIGVQEEDHVSAAIVKSIYKHIDTPFIVTSLAGAELIKYANNFFLAAKISFIN EMARICEAYQSDISDISRAIGLDPRIGKHFLQAGIGYGGSCFPKDLQALQFAAQEKNT ETFLLRAVQHINDTQLGLYIKKIQSFFETLQGKKAAVLGISFKPNTDDIRNSQAVRLM ERLAELGCDVHAYDPEAVLPEHLRQHVTQHSQAFDAIEESDFLFLATEWSEFLAFDWK KAADIMKGRLVIDGRNVLKKELIEACGLICTGVGRP*" gene 3021323..3022609 /gene="ytcA" /locus_tag="BSU_30860" /old_locus_tag="BSU30860" CDS 3022606..3023556 /gene="ytcB" /locus_tag="BSU_30870" /old_locus_tag="BSU30870" /EC_number="5.1.3.2" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative UDP-glucose epimerase" /protein_id="NP_390965.1" /db_xref="EnsemblGenomes-Gn:BSU30870" /db_xref="EnsemblGenomes-Tr:CAB15065" /db_xref="GOA:O34886" /db_xref="InterPro:IPR001509" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG13829" /db_xref="UniProtKB/Swiss-Prot:O34886" /translation="MKILVTGAAGFIGSHLCEELLKDKKHNVIGIDDFIGPTPFSLKL KNLKNLLPEKRFTFIKENLLTADLASLLEGVDVIFHLAAIPGVRSSWGNHFHPYAAHN IQALQRLLEACREHSIQTFVFASTSSVYGEKQGKVSENTSLSPLSPYGVTKLTGEKLC HVYKQSFGIPIVILRFFTVYGPRQRPDMAFHRLIKQHLQQKPLTIFGDGQQSRDFTYI SDCVKGITAVLGKPHLIGETVNIGGAERASVLKVVSLIEDISGRKATLHFSDKIAGEP SNTWADISKAKQLLHYDPATSLKDGLTNEIAYLSSLYQGE*" gene 3022606..3023556 /gene="ytcB" /locus_tag="BSU_30870" /old_locus_tag="BSU30870" CDS 3023559..3024782 /gene="ytcC" /locus_tag="BSU_30880" /old_locus_tag="BSU30880" /EC_number="2.4.1.-" /function="16.14: Store" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative glucosyltransferase" /protein_id="NP_390966.1" /db_xref="EnsemblGenomes-Gn:BSU30880" /db_xref="EnsemblGenomes-Tr:CAB15066" /db_xref="GOA:O34413" /db_xref="InterPro:IPR001296" /db_xref="InterPro:IPR028098" /db_xref="SubtiList:BG13830" /db_xref="UniProtKB/Swiss-Prot:O34413" /translation="MKLAFICTEKLPAPAVRGGAIQMMIDGVTPYFSSRYDLTIFSIE DPSLPKRETKDGVHYIHLPKEHYREAVAEELRASSFDLIHVFNRPLNVSLYKKASPNS KIVLSLHNEMFSEKKMTFAQGKEVLDNVSMITTVSEFIKQTVIERFPEAEDITKVVYS GVDLNSYPPVWTMKGSAVRKTYRKKYGIEDKKVILFAGRLSPTKGPHLLIHSMRRILQ QHPDAVLVIAGGKWFSDDSENQYVTYLRTLALPYRDHIIFTKFIPADDIPNLFLMADV FVCSSQWNEPLARVNYEAMAAGTPLITTNRGGNGEVVKHEVTGLVIDSYNKPSSFAKA IDRAFTDQELMNKMTKNARKHVEALFTFTHAAKRLNTVYQSVLTPKNKQFPPPFLTQN FDLSSINQLFVKAKT*" gene 3023559..3024782 /gene="ytcC" /locus_tag="BSU_30880" /old_locus_tag="BSU30880" downshifts complement(3024706) /Source="Nicolas_upshifts" /id="D1589" /incds=1 /nref=1 /ntot=10 /MaxReadThrough="1.32025" /MaxDrop="3.47267" /score="-3.65321449" /energy="-3.1" /TU="NA" /idTUdmin="U2395" /TUdmin=66 /isTUend="FALSE" S_feature 3024783..3025350 /Source="Nicolas_S_feature" /locus_tag="new_3159185_3159752" /HighExp="S8, S7, BT, S6, C30, Pyr, S5, G/S, C90, Glucon" /AntisenseName="ytxO" /AntisenseCor="0.86121563743373297" /AntisenseRegPval="-79.7" /CDS_PredictionProba="NA" /TUshortSig="SigK" /TUshortPSig="0.99" /TUlongSig="NA" /TUlongPSig="NA" /label="S1179" CDS complement(3024856..3025287) /gene="cotOO" /locus_tag="BSU_30890" /old_locus_tag="BSU30890" /experiment="publication(s) with functional evidences, PMID:19933362" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 19933362; Product type s: structure" /codon_start=1 /transl_table=11 /product="outer spore coat protein" /protein_id="NP_390967.1" /db_xref="EnsemblGenomes-Gn:BSU30890" /db_xref="EnsemblGenomes-Tr:CAB15067" /db_xref="SubtiList:BG11382" /db_xref="UniProtKB/Swiss-Prot:P46916" /translation="MRSSRQKASISKLDLDQFVFTPPGPMGWQAHDSISAEKEEEEKH LDVGSIRELPHINAPKEYQKETKEKETDRKIVDDEEETKFETTLEPEEERDSKRSAPP YEEEDEDEEPDLAEEAKVEIIILPSESKPAPWFSQTVKRKA*" gene complement(3024856..3025287) /gene="cotOO" /locus_tag="BSU_30890" /old_locus_tag="BSU30890" downshifts complement(3024882) /Source="Nicolas_upshifts" /id="D1590" /incds=0 /nref=11 /ntot=36 /MaxReadThrough="3.07378" /MaxDrop="4.8822" /score="9.30990044" /energy="-8.3" /TU="U2395" /idTUdmin="U2395" /TUdmin="-110" /isTUend="FALSE" CDS complement(3025289..3026344) /gene="cotS" /locus_tag="BSU_30900" /old_locus_tag="BSU30900" /function="16.5: Explore" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:7545510, 9603889, 10234840, 11737650, 14702409" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7545510, 9603889, 10234840, 11737650, 14702409; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="spore coat protein" /protein_id="NP_390968.1" /db_xref="EnsemblGenomes-Gn:BSU30900" /db_xref="EnsemblGenomes-Tr:CAB15068" /db_xref="GOA:P46914" /db_xref="InterPro:IPR011009" /db_xref="InterPro:IPR014255" /db_xref="SubtiList:BG11380" /db_xref="UniProtKB/Swiss-Prot:P46914" /translation="MYQKEHEEQIVSEILSYYPFHIDHVALKSNKSGRKIWEVETDHG PKLLKEAQMKPERMLFITQAHAHLQEKGLPIAPIHQTKNGGSCLGTDQVSYSLYDKVT GKEMIYYDAEQMKKVMSFAGHFHHASKGYVCTDESKKRSRLGKWHKLYRWKLQELEGN MQIAASYPDDVFSQTFLKHADKMLARGKEALRALDDSEYETWTKETLEHGGFCFQDFT LARLTEIEGEPFLKELHSITYDLPSRDLRILLNKVMVKLSVWDTDFMVALLAAYDAVY PLTEKQYEVLWIDLAFPHLFCAIGHKYYLKQKKTWSDEKYNWALQNMISVEESKDSFL DKLPELYKKIKAYREAN*" gene complement(3025289..3026344) /gene="cotS" /locus_tag="BSU_30900" /old_locus_tag="BSU30900" CDS complement(3026359..3027492) /gene="cotSA" /locus_tag="BSU_30910" /old_locus_tag="BSU30910" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:9603889, 10234840, 11737650" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9603889, 10234840, 11737650; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="spore coat protein" /protein_id="NP_390969.1" /db_xref="EnsemblGenomes-Gn:BSU30910" /db_xref="EnsemblGenomes-Tr:CAB15069" /db_xref="GOA:P46915" /db_xref="InterPro:IPR001296" /db_xref="InterPro:IPR028098" /db_xref="SubtiList:BG11381" /db_xref="UniProtKB/Swiss-Prot:P46915" /translation="MKIALIATEKLPVPSVRGGAIQIYLEAVAPLIAKKHEVTVFSIK DPNLADREKVDGVHYVHLDEDRYEEAVGAELKKSRFDLVHVCNRPSWVPKLKKQAPDA VFILSVHNEMFAYDKISQAEGEICIDSVAQIVTVSDYIGQTITSRFPSARSKTKTVYS GVDLKTYHPRWTNEGQRAREEMRSELGLHGKKIVLFVGRLSKVKGPHILLQALPDIIE EHPDVMMVFIGSKWFGDNELNNYVKHLHTLGAMQKDHVTFIQFVKPKDIPRLYTMSDV FVCSSQWQEPLARVHYEAMAAGLPIITSNRGGNPEVIEEGKNGYIIHDFENPKQYAER INDLLSSSEKRERLGKYSRREAESNFGWQRVAENLLSVYEKNR*" gene complement(3026359..3027492) /gene="cotSA" /locus_tag="BSU_30910" /old_locus_tag="BSU30910" promotor_-10 complement(3027525..3027544) /Source="Nicolas_upshift_promotors" /id="U2395" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=1345 /SigmaFactorBS="tctggttgtttacccgttttgtttttagggcagtcccaTTCC GCACAAgttggttgttcaGCCGTATCATGATTCTAACTagttaaaaatcatgcaggaa t" /listShort="cotSA, cotS, ytxO" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3027544) /Source="Nicolas_upshifts" /id="U2395" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=1345 /SigmaFactorBS="tctggttgtttacccgttttgtttttagggcagtcccaTTCC GCACAAgttggttgttcaGCCGTATCATGATTCTAACTagttaaaaatcatgcaggaa t" /listShort="cotSA, cotS, ytxO" /GFF_Attribute="listLong" promotor_-35 complement(3027557..3027566) /Source="Nicolas_upshift_promotors" /id="U2395" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=1345 /SigmaFactorBS="tctggttgtttacccgttttgtttttagggcagtcccaTTCC GCACAAgttggttgttcaGCCGTATCATGATTCTAACTagttaaaaatcatgcaggaa t" /listShort="cotSA, cotS, ytxO" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 3027630..3027639 /Source="Nicolas_upshift_promotors" /id="U2396" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=1346 /SigmaFactorBS="aacaaccagattcatctattaaatatagtcaaataACTCAAT CATtttttccttttgaTTCATAAGGTAGGAGTAAAAcaggtaaggatgtgtcctttaa t" /listShort="cotI, ytaB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3027653..3027672 /Source="Nicolas_upshift_promotors" /id="U2396" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=1346 /SigmaFactorBS="aacaaccagattcatctattaaatatagtcaaataACTCAAT CATtttttccttttgaTTCATAAGGTAGGAGTAAAAcaggtaaggatgtgtcctttaa t" /listShort="cotI, ytaB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3027655 /Source="Nicolas_upshifts" /id="U2396" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=1346 /SigmaFactorBS="aacaaccagattcatctattaaatatagtcaaataACTCAAT CATtttttccttttgaTTCATAAGGTAGGAGTAAAAcaggtaaggatgtgtcctttaa t" /listShort="cotI, ytaB" /GFF_Attribute="listLong" CDS 3027682..3028755 /gene="cotI" /locus_tag="BSU_30920" /old_locus_tag="BSU30920" /function="16.13: Shape" /function="16.5: Explore" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:12562816, 20077512" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12562816, 20077512; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="spore coat kinase" /protein_id="NP_390970.1" /db_xref="EnsemblGenomes-Gn:BSU30920" /db_xref="EnsemblGenomes-Tr:CAB15070" /db_xref="GOA:O34656" /db_xref="InterPro:IPR002575" /db_xref="InterPro:IPR011009" /db_xref="InterPro:IPR014255" /db_xref="PDB:2Q83" /db_xref="SubtiList:BG13821" /db_xref="UniProtKB/Swiss-Prot:O34656" /translation="MCPLMAENHEVIEEGNSSELPLSAEDAKKLTELAENVLQGWDVQ AEKIDVIQGNQMALVWKVHTDSGAVCLKRIHRPEKKALFSIFAQDYLAKKGMNVPGIL PNKKGSLYSKHGSFLFVVYDWIEGRPFELTVKQDLEFIMKGLADFHTASVGYQPPNGV PIFTKLGRWPNHYTKRCKQMETWKLMAEAEKEDPFSQLYLQEIDGFIEDGLRIKDRLL QSTYVPWTEQLKKSPNLCHQDYGTGNTLLGENEQIWVIDLDTVSFDLPIRDLRKMIIP LLDTTGVWDDETFNVMLNAYESRAPLTEEQKQVMFIDMLFPYELYDVIREKYVRKSAL PKEELESAFEYERIKANALRQLI*" gene 3027682..3028755 /gene="cotI" /locus_tag="BSU_30920" /old_locus_tag="BSU30920" promotor_-35 3027979..3027985 /Source="Nicolas_upshift_promotors" /id="U2397" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=785 /SigmaFactorBS="tttcgcgcaggactatttagcaaaaaaaggcatgaatgttcc tGGCATACtcccaaacaaaaaAGGCAGCCTATAttctaagcacggctcatttctattt g" /listShort="ytaB" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 3027996 /Source="Nicolas_upshifts" /id="U2397" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=785 /SigmaFactorBS="tttcgcgcaggactatttagcaaaaaaaggcatgaatgttcc tGGCATACtcccaaacaaaaaAGGCAGCCTATAttctaagcacggctcatttctattt g" /listShort="ytaB" /GFF_Attribute="listLong" promotor_-10 3027999..3028010 /Source="Nicolas_upshift_promotors" /id="U2397" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=785 /SigmaFactorBS="tttcgcgcaggactatttagcaaaaaaaggcatgaatgttcc tGGCATACtcccaaacaaaaaAGGCAGCCTATAttctaagcacggctcatttctattt g" /listShort="ytaB" /GFF_Attribute="listLong" /label="promotor_-10" downshifts 3028744 /Source="Nicolas_upshifts" /id="D1591" /incds=0 /nref=16 /ntot=35 /MaxReadThrough="3.14769" /MaxDrop="5.1897" /score="-2.47616606" /energy="-10.3" /TU="U2396,U2397" /idTUdmin="U2396" /TUdmin="-528" /isTUend="FALSE" promotor_-35 3028782..3028788 /Source="Nicolas_upshift_promotors" /id="U2398" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=240 /SigmaFactorBS="gcagcttatttaagaccatcatttcccccgcatatcgggGGT TTGAtatttataagataaaGGGTAATTAAATACATGCGgaggttgcaaatatgaaaaa g" /listShort="ytaB" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 3028803 /Source="Nicolas_upshifts" /id="U2398" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=240 /SigmaFactorBS="gcagcttatttaagaccatcatttcccccgcatatcgggGGT TTGAtatttataagataaaGGGTAATTAAATACATGCGgaggttgcaaatatgaaaaa g" /listShort="ytaB" /GFF_Attribute="listLong" promotor_-10 3028804..3028822 /Source="Nicolas_upshift_promotors" /id="U2398" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=240 /SigmaFactorBS="gcagcttatttaagaccatcatttcccccgcatatcgggGGT TTGAtatttataagataaaGGGTAATTAAATACATGCGgaggttgcaaatatgaaaaa g" /listShort="ytaB" /GFF_Attribute="listLong" /label="promotor_-10" CDS 3028835..3029302 /gene="ytaB" /locus_tag="BSU_30930" /old_locus_tag="BSU30930" /function="16.12: Sense" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 11717291, 15849754, 16850406; Product type rc: receptor" /codon_start=1 /transl_table=11 /product="putative receptor" /protein_id="NP_390971.1" /db_xref="EnsemblGenomes-Gn:BSU30930" /db_xref="EnsemblGenomes-Tr:CAB15071" /db_xref="GOA:O34694" /db_xref="InterPro:IPR004307" /db_xref="SubtiList:BG13822" /db_xref="UniProtKB/Swiss-Prot:O34694" /translation="MKKIVGALAVFVITYALFSAAGYLFPVDQEWYNSLKKPDWTPSG TAIGIIWAILFALISLSAAIVYAAFSFKGAKSFWFTLLINYVLNQAFSYFQFTQKNLL AASLDCLLVAITAIVLLIIAKKYSRAASYLLLPYFLWSAFATFLSFTINSMNL*" gene 3028835..3029302 /gene="ytaB" /locus_tag="BSU_30930" /old_locus_tag="BSU30930" downshifts 3029274 /Source="Nicolas_upshifts" /id="D1592" /incds=0 /nref=43 /ntot=123 /MaxReadThrough="2.47485" /MaxDrop="5.7907" /score="9.10214462" /energy="-10.1" /TU="NA" /idTUdmin="U2396" /TUdmin=2 /isTUend="TRUE" CDS complement(3029333..3031729) /gene="glgP" /locus_tag="BSU_30940" /old_locus_tag="BSU30940" /EC_number="2.4.1.1" /function="16.14: Store" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1c: Function from experimental evidences in the studied genus; PubMedId: 8145641, 9244254, 15272305; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="glycogen phosphorylase" /protein_id="NP_390972.1" /db_xref="EnsemblGenomes-Gn:BSU30940" /db_xref="EnsemblGenomes-Tr:CAB15072" /db_xref="GOA:P39123" /db_xref="InterPro:IPR000811" /db_xref="InterPro:IPR011833" /db_xref="InterPro:IPR035090" /db_xref="SubtiList:BG10911" /db_xref="UniProtKB/Swiss-Prot:P39123" /translation="MFSSKERFADLFLKRLEMTCGKSFKDSAKLDQYKTLGNMVREYI SADWIETNEKSRSNSGKQTYYLSIEFLLGQLLEQNLMNLGVRDVVEAGLKEIGINLEE ILQIENDAGLGNGGLGRLAACFLDSLASLNLPGHGMGIRYKHGLFEQKIVDGHQVELP EQWLKNGNVWEVRNADQAVDVPFWGEVHMTEKSGRLHFRHEQATIVTAVPYDIPIIGY ETGTVNTLRLWNAEPYAHYHGGNILSYKRETEAVSEFLYPDDTHDEGKILRLKQQYFL VCASLKSIVNNYRKTHKSLSGLHKKVSIHINDTHPALAVPELMRILLDEENMSWEEAW HITVHTISYTNHTTLSEALEKWPIHLFKPLLPRMYMIIEEINERFCRAVWEKYPGDWK RIENMAITAHGVVKMAHLAIVGSYSVNGVAKIHSDILKEREMRDFHLLFPNRFNNKTN GIAHRRWLLKANPGLSAIITEAIGDEWVKQPESLIRLEPYATDPAFIEQFQNNKSKKK QELADLIFCTAGVVVNPESIFDVQVKRLHAYKRQLLNVLHIMYLYNRLKEDSGFSIYP QTFIFGAKASPSYYYAKKIIKLIHSVAEKVNYDPAVKQLIKVVFLENYRVSMAERIFP ASDVSEQISTASKEASGTGNMKFMMNGALTIGTHDGANIEILERVGPDCIYTFGLKAD EVLSYQENGGYRSREYYQHDRRIRQVADQLINGFFEGEADEFESIFDSLLPHNDEYFV LKDFSSYADAQERIQADYRERRKWSEHSIVNIAHSGYFSSDRTIREYAKDIWGIKPMM *" gene complement(3029333..3031729) /gene="glgP" /locus_tag="BSU_30940" /old_locus_tag="BSU30940" downshifts complement(3029348) /Source="Nicolas_upshifts" /id="D1593" /incds=0 /nref=6 /ntot=43 /MaxReadThrough="2.31076" /MaxDrop="4.39135" /score="34.694666" /energy="-10.1" /TU="NA" /idTUdmin="U2399" /TUdmin=0 /isTUend="TRUE" CDS complement(3031716..3033170) /gene="glgA" /locus_tag="BSU_30950" /old_locus_tag="BSU30950" /EC_number="2.4.1.21" /function="16.14: Store" /experiment="publication(s) with functional evidences, PMID:8145641, 15272305" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8145641, 15272305; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="glycogen (starch) synthase" /protein_id="NP_390973.1" /db_xref="EnsemblGenomes-Gn:BSU30950" /db_xref="EnsemblGenomes-Tr:CAB15073" /db_xref="GOA:P39125" /db_xref="InterPro:IPR001296" /db_xref="InterPro:IPR011835" /db_xref="InterPro:IPR013534" /db_xref="SubtiList:BG10910" /db_xref="UniProtKB/Swiss-Prot:P39125" /translation="MKILFAVSECTPFVKSGGLADVAGALPKALARLGNEVAVMLPKY SQIPEPWKKRMKKQAECTVAVGWRQQYCGIEHMAENDVNYYFIDNEYYFNRDSLYGHY DDGERFAFFSRAVLEAAKVVNVQADIVHTHDWHTAMVNYLLKEEYRKHPFYERMKSVL TIHNLQFQGIFPPDVTHDLLGLEMDHFHYERLECNGFVNFMKAGIIAADHVTTVSPTY RNEIMTPYYGEQLEQVLQYREDDVTGILNGIDDTFYQPKSDPYIEAQYDSGDLACKLE NKTKLQQRMGLPEKNDIPLISMVTRLTKQKGLDLVRRIMHELLEEQDIQLVVLGTGER EFEDYFRYAEFAFHEKCRAYIGFDEPLAHQIYAGSDMFLMPSKFEPCGLGQLIALQYG AIPIVRETGGLYDTVRAYQEEEGTGNGFTFSAFNAHDLKFTIERALSFYCQQDVWKSI VKTAMNADYSWGKSAKEYQRIFEQVTRSGRDVLE*" gene complement(3031716..3033170) /gene="glgA" /locus_tag="BSU_30950" /old_locus_tag="BSU30950" CDS complement(3033167..3034198) /gene="glgD" /locus_tag="BSU_30960" /old_locus_tag="BSU30960" /EC_number="2.7.7.27" /function="16.14: Store" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 8145641, 9244254; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="glucose-1-phosphate adenylyltransferase (ADP-glucose pyrophosphorylase) beta subunit" /protein_id="NP_390974.1" /db_xref="EnsemblGenomes-Gn:BSU30960" /db_xref="EnsemblGenomes-Tr:CAB15074" /db_xref="GOA:P39124" /db_xref="InterPro:IPR005835" /db_xref="InterPro:IPR011004" /db_xref="InterPro:IPR011832" /db_xref="InterPro:IPR029044" /db_xref="SubtiList:BG10909" /db_xref="UniProtKB/Swiss-Prot:P39124" /translation="MFNNQMLGVIDETTYKHSLQDLTAQRSLGAIPFAGRYRLIDFML SNMVNADIRSVAIFPKYRYRSLMDHLGAGKEWDLHRKKDGLFFFPSPHLHHEYDEFGS FRQFSDHLDYFHRSTQQYAVISNSHTVCNIQFQYVLKRHQEVGCDVTEVFQDGQSLQI YIMSTTLLKDLIYGHSEKGYKTIQEAVEKESSALTICPYEYSGYAAVIDSVEKYYTHS MELIQPRFWQQVFLPQQPIYTKVKDEPPTKYGKHSTVKNSLVANGCVLEGEVENCILF RAVHVGKGTKLKNCIIMQKTQIGEDCLLEQVISDKDVKIGKATEAAGTAEQPLVLRKG LVQGELMNS*" gene complement(3033167..3034198) /gene="glgD" /locus_tag="BSU_30960" /old_locus_tag="BSU30960" CDS complement(3034222..3035364) /gene="glgC" /locus_tag="BSU_30970" /old_locus_tag="BSU30970" /EC_number="2.7.7.27" /function="16.14: Store" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 8145641, 9244254; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="glucose-1-phosphate adenylyltransferase (ADP-glucose pyrophosphorylase) subunit alpha" /protein_id="NP_390975.1" /db_xref="EnsemblGenomes-Gn:BSU30970" /db_xref="EnsemblGenomes-Tr:CAB15075" /db_xref="GOA:P39122" /db_xref="InterPro:IPR005835" /db_xref="InterPro:IPR005836" /db_xref="InterPro:IPR011004" /db_xref="InterPro:IPR011831" /db_xref="InterPro:IPR023049" /db_xref="InterPro:IPR029044" /db_xref="SubtiList:BG10908" /db_xref="UniProtKB/Swiss-Prot:P39122" /translation="MKKQCVAMLLAGGKGSRLSGLTKNMAKPAVSFGGKYRIIDFTLS NCSNSGIDTVGILTQYQPLELNSYIGIGSAWDLDRYNGGVTVLPPYAESSEVKWYKGT ASSIYENLNYLNQYDPEYVLILSGDHIYKMDYGKMLDYHIEKKADVTISVIEVGWEEA SRFGIMKANPDGTITHFDEKPKFPKSNLASMGIYIFNWPLLKQYLEMDDQNPYSSHDF GKDIIPLLLEEKKKLSAYPFKGYWKDVGTVQSLWEANMDLLKEDSELKLFERKWKIYS VNPNQPPQFISSDAQVQDSLVNEGCVVYGNVSHSVLFQGVTVGKHTTVTSSVIMPDVT IGEHVVIENAIVPNGMVLPDGAVIRSEKDIEEVLLVSEEFVEKELI*" gene complement(3034222..3035364) /gene="glgC" /locus_tag="BSU_30970" /old_locus_tag="BSU30970" CDS complement(3035361..3037244) /gene="glgB" /locus_tag="BSU_30980" /old_locus_tag="BSU30980" /EC_number="2.4.1.18" /function="16.14: Store" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 1296817, 15272305, 8145641; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="1,4-alpha-glucan branching enzyme" /protein_id="NP_390976.1" /db_xref="EnsemblGenomes-Gn:BSU30980" /db_xref="EnsemblGenomes-Tr:CAB15076" /db_xref="GOA:P39118" /db_xref="InterPro:IPR004193" /db_xref="InterPro:IPR006047" /db_xref="InterPro:IPR006048" /db_xref="InterPro:IPR006407" /db_xref="InterPro:IPR013783" /db_xref="InterPro:IPR014756" /db_xref="InterPro:IPR017853" /db_xref="SubtiList:BG10907" /db_xref="UniProtKB/Swiss-Prot:P39118" /translation="MAAASPTAHDVYLFHEGSLFKSYQLFGSHYRELNGKSGYEFCVW APHASEVRVAGDFNSWSGEEHVMHRVNDNGIWTLFIPGIGEKERYKYEIVTNNGEIRL KADPYAIYSEVRPNTASLTYDLEGYSWQDQKWQKKQKAKTLYEKPVFIYELHLGSWKK HSDGRHYSYKELSQTLIPYIKKHGFTHIELLPVYEHPYDRSWGYQGTGYYSPTSRFGP PHDLMKFVDECHQQNIGVILDWVPGHFCKDAHGLYMFDGEPLYEYKEERDRENWLWGT ANFDLGKPEVHSFLISNALYWAEFYHIDGFRVDAVANILYWPNQDERHTNPYAVDFLK KLNQTMREAYPHVMMIAEDSTEWPQVTGAVEEGGLGFHYKWNMGWMNDVLKYMETPPE ERRHCHQLISFSLLYAFSEHFVLPFSHDEVVYGKKSLLNKMPGDYWQKFAQYRLLLGY MTVHPGKKLIFMGSEFAQFDEWKDTEQLDWFLDSFPMHQKASVFTQDLLRFYQKSKIL YEHDHRAQSFEWIDVHNDEQSIFSFIRYGQKHGEALVIICNFTPVVYHQYDVGVPFFT QYIEVLNSDSETYGGSGQINKKPLSAKKGALHHKPCYITMTIPPYGISILRAVKKRGE IKR*" gene complement(3035361..3037244) /gene="glgB" /locus_tag="BSU_30980" /old_locus_tag="BSU30980" S_feature 3036070..3037489 /Source="Nicolas_S_feature" /locus_tag="new_3170472_3171891" /HighExp="S8, S7, S6, C30, BT, Pyr, G/S, S2, C90, BC" /AntisenseName="glgB" /AntisenseCor="0.59299722159013002" /AntisenseRegPval="-26.2" /CDS_PredictionProba="NA" /TUshortSig="NA" /TUshortPSig="NA" /TUlongSig="NA" /TUlongPSig="NA" /label="S1180" promotor_-10 complement(3037276..3037291) /Source="Nicolas_upshift_promotors" /id="U2399" /multdbtbs="SigE" /comp="M1" /sig="Sig-" /pcomp="0.414585414585415" /psig="0.414585414585415" /xcortree=1175 /SigmaFactorBS="gaagttaattgtctataagtataagcgctttcaggaaaGGGC TTttttttatttcttcGAATAAATACTATAAAtgaaaactatgatgtcagaaaggatg a" /listShort="glgB, glgC, glgD, glgA, glgP" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3037289) /Source="Nicolas_upshifts" /id="U2399" /multdbtbs="SigE" /comp="M1" /sig="Sig-" /pcomp="0.414585414585415" /psig="0.414585414585415" /xcortree=1175 /SigmaFactorBS="gaagttaattgtctataagtataagcgctttcaggaaaGGGC TTttttttatttcttcGAATAAATACTATAAAtgaaaactatgatgtcagaaaggatg a" /listShort="glgB, glgC, glgD, glgA, glgP" /GFF_Attribute="listLong" promotor_-35 complement(3037306..3037311) /Source="Nicolas_upshift_promotors" /id="U2399" /multdbtbs="SigE" /comp="M1" /sig="Sig-" /pcomp="0.414585414585415" /psig="0.414585414585415" /xcortree=1175 /SigmaFactorBS="gaagttaattgtctataagtataagcgctttcaggaaaGGGC TTttttttatttcttcGAATAAATACTATAAAtgaaaactatgatgtcagaaaggatg a" /listShort="glgB, glgC, glgD, glgA, glgP" /GFF_Attribute="listLong" /label="promotor_-35" downshifts complement(3037356) /Source="Nicolas_upshifts" /id="D1594" /incds=0 /nref=2 /ntot=46 /MaxReadThrough="1.66182" /MaxDrop="3.12741" /score="36.0363304" /energy="-9.2" /TU="NA" /idTUdmin="U2401" /TUdmin=198 /isTUend="FALSE" tRNA complement(3037477..3037548) /gene="trnB-Glu" /locus_tag="BSU_tRNA_72" /product="tRNA-Glu" /inference="profile:tRNAscan:1.23" /note="Evidence 2a: Function from experimental evidences in other organisms; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene complement(3037477..3037548) /gene="trnB-Glu" /locus_tag="BSU_tRNA_72" tRNA complement(3037574..3037664) /gene="trnB-Ser2" /locus_tag="BSU_tRNA_71" /product="tRNA-Ser" /inference="profile:tRNAscan:1.23" /note="Evidence 2a: Function from experimental evidences in other organisms; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene complement(3037574..3037664) /gene="trnB-Ser2" /locus_tag="BSU_tRNA_71" tRNA complement(3037668..3037742) /gene="trnB-Asn" /locus_tag="BSU_tRNA_70" /product="tRNA-Asn" /inference="profile:tRNAscan:1.23" /note="Evidence 2a: Function from experimental evidences in other organisms; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene complement(3037668..3037742) /gene="trnB-Asn" /locus_tag="BSU_tRNA_70" tRNA complement(3037753..3037829) /gene="trnB-Ile2" /locus_tag="BSU_tRNA_69" /product="tRNA-Ile" /inference="profile:tRNAscan:1.23" /note="Evidence 2a: Function from experimental evidences in other organisms; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene complement(3037753..3037829) /gene="trnB-Ile2" /locus_tag="BSU_tRNA_69" tRNA complement(3037845..3037918) /gene="trnB-Gly2" /locus_tag="BSU_tRNA_68" /product="tRNA-Gly" /inference="profile:tRNAscan:1.23" /note="Evidence 2a: Function from experimental evidences in other organisms; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene complement(3037845..3037918) /gene="trnB-Gly2" /locus_tag="BSU_tRNA_68" tRNA complement(3037929..3038004) /gene="trnB-His" /locus_tag="BSU_tRNA_67" /product="tRNA-His" /inference="profile:tRNAscan:1.23" /note="Evidence 2a: Function from experimental evidences in other organisms; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene complement(3037929..3038004) /gene="trnB-His" /locus_tag="BSU_tRNA_67" tRNA complement(3038022..3038097) /gene="trnB-Phe" /locus_tag="BSU_tRNA_66" /product="tRNA-Phe" /inference="profile:tRNAscan:1.23" /note="Evidence 2a: Function from experimental evidences in other organisms; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene complement(3038022..3038097) /gene="trnB-Phe" /locus_tag="BSU_tRNA_66" tRNA complement(3038110..3038186) /gene="trnB-Asp" /locus_tag="BSU_tRNA_65" /product="tRNA-Asp" /inference="profile:tRNAscan:1.23" /note="Evidence 2a: Function from experimental evidences in other organisms; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene complement(3038110..3038186) /gene="trnB-Asp" /locus_tag="BSU_tRNA_65" tRNA complement(3038198..3038274) /gene="trnB-Met2" /locus_tag="BSU_tRNA_64" /product="tRNA-Met" /inference="profile:tRNAscan:1.23" /note="Evidence 2a: Function from experimental evidences in other organisms; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene complement(3038198..3038274) /gene="trnB-Met2" /locus_tag="BSU_tRNA_64" tRNA complement(3038292..3038384) /gene="trnB-Ser1" /locus_tag="BSU_tRNA_63" /product="tRNA-Ser" /inference="profile:tRNAscan:1.23" /note="Evidence 2a: Function from experimental evidences in other organisms; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene complement(3038292..3038384) /gene="trnB-Ser1" /locus_tag="BSU_tRNA_63" tRNA complement(3038391..3038467) /gene="trnB-Met3" /locus_tag="BSU_tRNA_62" /product="tRNA-Met" /inference="profile:tRNAscan:1.23" /note="Evidence 2a: Function from experimental evidences in other organisms; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene complement(3038391..3038467) /gene="trnB-Met3" /locus_tag="BSU_tRNA_62" tRNA complement(3038470..3038546) /gene="trnB-Met1" /locus_tag="BSU_tRNA_61" /product="tRNA-Met" /inference="profile:tRNAscan:1.23" /note="Evidence 2a: Function from experimental evidences in other organisms; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene complement(3038470..3038546) /gene="trnB-Met1" /locus_tag="BSU_tRNA_61" tRNA complement(3038566..3038638) /gene="trnB-Ala" /locus_tag="BSU_tRNA_60" /product="tRNA-Ala" /inference="profile:tRNAscan:1.23" /note="Evidence 2a: Function from experimental evidences in other organisms; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene complement(3038566..3038638) /gene="trnB-Ala" /locus_tag="BSU_tRNA_60" tRNA complement(3038644..3038720) /gene="trnB-Pro" /locus_tag="BSU_tRNA_59" /product="tRNA-Pro" /inference="profile:tRNAscan:1.23" /note="Evidence 2a: Function from experimental evidences in other organisms; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene complement(3038644..3038720) /gene="trnB-Pro" /locus_tag="BSU_tRNA_59" tRNA complement(3038736..3038812) /gene="trnB-Arg" /locus_tag="BSU_tRNA_58" /product="tRNA-Arg" /inference="profile:tRNAscan:1.23" /note="Evidence 2a: Function from experimental evidences in other organisms; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene complement(3038736..3038812) /gene="trnB-Arg" /locus_tag="BSU_tRNA_58" tRNA complement(3038822..3038907) /gene="trnB-Leu2" /locus_tag="BSU_tRNA_57" /product="tRNA-Leu" /inference="profile:tRNAscan:1.23" /note="Evidence 2a: Function from experimental evidences in other organisms; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene complement(3038822..3038907) /gene="trnB-Leu2" /locus_tag="BSU_tRNA_57" tRNA complement(3038922..3038996) /gene="trnB-Gly1" /locus_tag="BSU_tRNA_56" /product="tRNA-Gly" /inference="profile:tRNAscan:1.23" /note="Evidence 2a: Function from experimental evidences in other organisms; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene complement(3038922..3038996) /gene="trnB-Gly1" /locus_tag="BSU_tRNA_56" tRNA complement(3039002..3039088) /gene="trnB-Leu1" /locus_tag="BSU_tRNA_55" /product="tRNA-Leu" /inference="profile:tRNAscan:1.23" /note="Evidence 2a: Function from experimental evidences in other organisms; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene complement(3039002..3039088) /gene="trnB-Leu1" /locus_tag="BSU_tRNA_55" tRNA complement(3039099..3039174) /gene="trnB-Lys" /locus_tag="BSU_tRNA_54" /product="tRNA-Lys" /inference="profile:tRNAscan:1.23" /note="Evidence 2a: Function from experimental evidences in other organisms; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene complement(3039099..3039174) /gene="trnB-Lys" /locus_tag="BSU_tRNA_54" tRNA complement(3039212..3039287) /gene="trnB-Thr" /locus_tag="BSU_tRNA_53" /product="tRNA-Thr" /inference="profile:tRNAscan:1.23" /note="Evidence 2a: Function from experimental evidences in other organisms; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene complement(3039212..3039287) /gene="trnB-Thr" /locus_tag="BSU_tRNA_53" tRNA complement(3039320..3039395) /gene="trnB-Val" /locus_tag="BSU_tRNA_52" /product="tRNA-Val" /inference="profile:tRNAscan:1.23" /note="Evidence 2a: Function from experimental evidences in other organisms; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene complement(3039320..3039395) /gene="trnB-Val" /locus_tag="BSU_tRNA_52" rRNA complement(3039416..3039533) /gene="rrnB-5S" /locus_tag="BSU_rRNA_21" /product="ribosomal RNA-5S" /note="Evidence 1a: Function from experimental evidences in the studied strain; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene complement(3039416..3039533) /gene="rrnB-5S" /locus_tag="BSU_rRNA_21" rRNA complement(3039589..3042516) /gene="rrnB-23S" /locus_tag="BSU_rRNA_20" /product="ribosomal RNA-23S" /note="Evidence 1a: Function from experimental evidences in the studied strain; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene complement(3039589..3042516) /gene="rrnB-23S" /locus_tag="BSU_rRNA_20" rRNA complement(3042684..3044238) /gene="rrnB-16S" /locus_tag="BSU_rRNA_19" /product="ribosomal RNA-16S" /note="Evidence 1a: Function from experimental evidences in the studied strain; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene complement(3042684..3044238) /gene="rrnB-16S" /locus_tag="BSU_rRNA_19" S_feature complement(3044239..3044530) /Source="Nicolas_S_feature" /locus_tag="new_3178641_3178932_c" /HighExp="Diami, LPhT, C30, LBGstat, HPh, GM 120, Oxctl, Paraq, LPh, dia0" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.40784100000000001" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="SigWXY" /TUlongPSig=1 /label="S1181" misc_feature 3044366..3044374 /Source="Nicolas_upshift_promotors" /id="U2400" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.413586413586414" /psig="0.320679320679321" /xcortree=710 /SigmaFactorBS="tgactacgcacatcgcagtgcgatttttaaaaactgaattaa caggtacgttttGTCTTGTTTagttttcaaagatcatttcgttacttctcaatgaagc a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 3044372 /Source="Nicolas_upshifts" /id="U2400" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.413586413586414" /psig="0.320679320679321" /xcortree=710 /SigmaFactorBS="tgactacgcacatcgcagtgcgatttttaaaaactgaattaa caggtacgttttGTCTTGTTTagttttcaaagatcatttcgttacttctcaatgaagc a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" downshifts 3044482 /Source="Nicolas_upshifts" /id="D1595" /incds=0 /nref=2 /ntot=26 /MaxReadThrough="2.91899" /MaxDrop="4.63941" /score="-0.368124787" /energy="-10.2" /TU="U2400" /idTUdmin="U2400" /TUdmin="-22" /isTUend="TRUE" promotor_-10 complement(3044503..3044522) /Source="Nicolas_upshift_promotors" /id="U2401" /multdbtbs="SigA" /comp="M17" /sig="SigA" /pcomp="0.997002997002997" /psig=1 /xcortree=2621 /SigmaFactorBS="ggcgaggattatagtttatttgttttatagattttttttaaa aaactATTGCAATaaataaatacaggTGTTATATTATTAAACGTCGctgatgcacagc g" /listShort="S1181, rrnB-16S, rrnB-23S, rrnB-5S, trnB-Val, trnB-Thr, trnB-Lys, trnB-Leu1, trnB-Gly1, trnB-Leu2, trnB-Arg, trnB-Pro, trnB-Ala, trnB-Met1, trnB-Met3, trnB-Ser1, trnB-Met2, trnB-Asp, trnB-Phe, trnB-His, trnB-Gly2, trnB-Ile2, trnB-Asn, trnB-Ser2" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3044530) /Source="Nicolas_upshifts" /id="U2401" /multdbtbs="SigA" /comp="M17" /sig="SigA" /pcomp="0.997002997002997" /psig=1 /xcortree=2621 /SigmaFactorBS="ggcgaggattatagtttatttgttttatagattttttttaaa aaactATTGCAATaaataaatacaggTGTTATATTATTAAACGTCGctgatgcacagc g" /listShort="S1181, rrnB-16S, rrnB-23S, rrnB-5S, trnB-Val, trnB-Thr, trnB-Lys, trnB-Leu1, trnB-Gly1, trnB-Leu2, trnB-Arg, trnB-Pro, trnB-Ala, trnB-Met1, trnB-Met3, trnB-Ser1, trnB-Met2, trnB-Asp, trnB-Phe, trnB-His, trnB-Gly2, trnB-Ile2, trnB-Asn, trnB-Ser2" /GFF_Attribute="listLong" S_feature complement(3044532..3045498) /Source="Nicolas_S_feature" /locus_tag="new_3178934_3179900_c" /HighExp="T1.0H, T0.30H, T1.30H, T2.0H, T2.30H, T0.0H, T3.0H, T-0.40H, S8, T3.30H" /AntisenseName="thiT" /AntisenseCor="-0.219467435413819" /AntisenseRegPval="-3.5" /CDS_PredictionProba="NA" /TUshortSig="SigWXY" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1182" promotor_-35 complement(3044536..3044543) /Source="Nicolas_upshift_promotors" /id="U2401" /multdbtbs="SigA" /comp="M17" /sig="SigA" /pcomp="0.997002997002997" /psig=1 /xcortree=2621 /SigmaFactorBS="ggcgaggattatagtttatttgttttatagattttttttaaa aaactATTGCAATaaataaatacaggTGTTATATTATTAAACGTCGctgatgcacagc g" /listShort="S1181, rrnB-16S, rrnB-23S, rrnB-5S, trnB-Val, trnB-Thr, trnB-Lys, trnB-Leu1, trnB-Gly1, trnB-Leu2, trnB-Arg, trnB-Pro, trnB-Ala, trnB-Met1, trnB-Met3, trnB-Ser1, trnB-Met2, trnB-Asp, trnB-Phe, trnB-His, trnB-Gly2, trnB-Ile2, trnB-Asn, trnB-Ser2" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 3044655..3044658 /Source="Nicolas_upshift_promotors" /id="U2402" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.971028971028971" /psig=1 /xcortree=1747 /SigmaFactorBS="tatcatataagtttcttaaaagaacatatacatcagtcatgt gatCTTGttgtttttttcgttTTCTTGTATAGTAGAAACGAactaaatactgatgacc a" /listShort="NA, thiT" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 3044670 /Source="Nicolas_upshifts" /id="U2402" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.971028971028971" /psig=1 /xcortree=1747 /SigmaFactorBS="tatcatataagtttcttaaaagaacatatacatcagtcatgt gatCTTGttgtttttttcgttTTCTTGTATAGTAGAAACGAactaaatactgatgacc a" /listShort="NA, thiT" /GFF_Attribute="listLong" promotor_-10 3044673..3044692 /Source="Nicolas_upshift_promotors" /id="U2402" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.971028971028971" /psig=1 /xcortree=1747 /SigmaFactorBS="tatcatataagtttcttaaaagaacatatacatcagtcatgt gatCTTGttgtttttttcgttTTCTTGTATAGTAGAAACGAactaaatactgatgacc a" /listShort="NA, thiT" /GFF_Attribute="listLong" /label="promotor_-10" misc_RNA 3044703..3044804 /gene="tswC" /locus_tag="BSU_misc_RNA_51" /product="thiamine pyrophosphate riboswitch" /note="Evidence 1c: Function from experimental evidences in the studied genus; PubMedId: 11470904, 12410317, 15862294, 16728979, 16962976, 17307816, 18179415, 18776013; Product type n: RNA" /function="16.3: Control" gene 3044703..3044804 /gene="tswC" /locus_tag="BSU_misc_RNA_51" downshifts 3044803 /Source="Nicolas_upshifts" /id="D1596" /incds=0 /nref=47 /ntot=135 /MaxReadThrough="5.85975" /MaxDrop="7.03111" /score="-0.368124787" /energy="-10.2" /TU="U2402" /idTUdmin="U2400" /TUdmin=299 /isTUend="FALSE" CDS 3044904..3045482 /gene="thiT" /locus_tag="BSU_30990" /old_locus_tag="BSU30990" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:15849754, 16291685, 16356850, 16850406, 19181806" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15849754, 16291685, 16356850, 16850406, 19181806; Product type t : transporter" /codon_start=1 /transl_table=11 /product="thiamin permease" /protein_id="NP_390977.1" /db_xref="EnsemblGenomes-Gn:BSU30990" /db_xref="EnsemblGenomes-Tr:CAB15077" /db_xref="GOA:O32074" /db_xref="InterPro:IPR012651" /db_xref="SubtiList:BG13949" /db_xref="UniProtKB/Swiss-Prot:O32074" /translation="MNQSKQLVRLIEIAIMTAAAVILDIVSGMFLSMPQGGSVSIMMI PIFLISFRWGVKAGLTTGLLTGLVQIAIGNLFAQHPVQLLLDYIVAFAAIGISGCFAS SVRKAAVSKTKGKLIVSVVSAVFIGSLLRYAAHVISGAVFFGSFAPKGTPVWIYSLTY NATYMVPSFIICAIVLCLLFMTAPRLLKSDKA*" gene 3044904..3045482 /gene="thiT" /locus_tag="BSU_30990" /old_locus_tag="BSU30990" downshifts 3045472 /Source="Nicolas_upshifts" /id="D1597" /incds=0 /nref=129 /ntot=206 /MaxReadThrough="1.91553" /MaxDrop="5.49387" /score="35.5376279" /energy="-19.5" /TU="NA" /idTUdmin="U2402" /TUdmin=0 /isTUend="TRUE" CDS complement(3045524..3046045) /gene="yuaI" /locus_tag="BSU_31000" /old_locus_tag="BSU31000" /EC_number="2.3.1.-" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative N-acetyltransferase" /protein_id="NP_390978.1" /db_xref="EnsemblGenomes-Gn:BSU31000" /db_xref="EnsemblGenomes-Tr:CAB15078" /db_xref="GOA:O32075" /db_xref="InterPro:IPR000182" /db_xref="InterPro:IPR016181" /db_xref="SubtiList:BG13948" /db_xref="UniProtKB/Swiss-Prot:O32075" /translation="MVTVREAKLEDIKDIAKVHVDSWRTTYHEIIPIDYLNSLNYKEF EDKWKSRSLKGVFVAQDEKGSVFGFASFGPIRSEQEGYDGELYAIYLLEERQRQGAGR ALLAKGAEFLLQHGFSSMFVWVIEQNPSIIFYQAYSPERVAEDNFEIAGVRLKEVGLG WPDLSALKTLLNR*" gene complement(3045524..3046045) /gene="yuaI" /locus_tag="BSU_31000" /old_locus_tag="BSU31000" downshifts complement(3045542) /Source="Nicolas_upshifts" /id="D1598" /incds=0 /nref=8 /ntot=143 /MaxReadThrough="6.18352" /MaxDrop="5.43101" /score="13.1646679" /energy="-19.6" /TU="U2403" /idTUdmin="U2405" /TUdmin=6 /isTUend="TRUE" downshifts complement(3045614) /Source="Nicolas_upshifts" /id="D1599" /incds=1 /nref=8 /ntot=208 /MaxReadThrough="8.2849" /MaxDrop="3.3545" /score="13.1646679" /energy="-19.6" /TU="U2403,U2405" /idTUdmin="U2405" /TUdmin="-66" /isTUend="FALSE" CDS complement(3046063..3047592) /gene="floT" /locus_tag="BSU_31010" /old_locus_tag="BSU31010" /experiment="publication(s) with functional evidences, PMID:9153235, 9987136, 12533473, 17482313, 19383680, 25635948, 26297017, 28681845" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9153235, 9987136, 12533473, 17482313, 19383680, 25635948, 26297017, 28681845; Product type s: structure" /codon_start=1 /transl_table=11 /product="flotillin lipid rafts scaffold protein" /protein_id="NP_390979.1" /db_xref="EnsemblGenomes-Gn:BSU31010" /db_xref="EnsemblGenomes-Tr:CAB15079" /db_xref="GOA:O32076" /db_xref="InterPro:IPR001107" /db_xref="InterPro:IPR027705" /db_xref="InterPro:IPR031905" /db_xref="InterPro:IPR036013" /db_xref="SubtiList:BG13947" /db_xref="UniProtKB/Swiss-Prot:O32076" /translation="MTMPIIMIIGVVFFLLIALIAVFITKYRTAGPDEALIVTGSYLG NKNVHVDEGGNRIKIVRGGGTFVLPVFQQAEPLSLLSSKLDVSTPEVYTEQGVPVMAD GTAIIKIGGSIGEIATAAEQFLGKSKDDREQEAREVLEGHLRSILGSMTVEEIYKNRE KFSQEVQRVASQDLAKMGLVIVSFTIKDVRDKNGYLESLGKPRIAQVKRDADIATAEA DKETRIKRAEADKDAKKSELERATEIAEAEKINQLKMAEFRREQDTAKANADQAYDLE TARARQQVTEQEMQVKIIERQKQIELEEKEILRRERQYDSEVKKKADADRYSVEQSAA AEKAKQLAEADAKKYSIEAMAKAEAEKVRIDGLAKAEAEKAKGETEAEVIRLKGLAEA EAKEKIAAAFEQYGQAAIFDMIVKMLPEYAKQAAAPLSNIDKITVVDTGGSGESSGAN KVTSYATNLMSSLQESLKASSGIDVKEMLENFSGKGNVKQSINELTNEIKEAKTIQKS E*" gene complement(3046063..3047592) /gene="floT" /locus_tag="BSU_31010" /old_locus_tag="BSU31010" CDS complement(3047613..3048137) /gene="nfeDB" /locus_tag="BSU_31020" /old_locus_tag="BSU31020" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 12533473, 15849754, 16850406, 18696230, 22753055; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative membrane integrity integral membrane protein" /protein_id="NP_390980.1" /db_xref="EnsemblGenomes-Gn:BSU31020" /db_xref="EnsemblGenomes-Tr:CAB15080" /db_xref="GOA:O32077" /db_xref="PDB:2K14" /db_xref="SubtiList:BG13946" /db_xref="UniProtKB/Swiss-Prot:O32077" /translation="MELFGVPIQTMYLYTLIIAGSLTLLFLFFGDVFSGLSEGIPFLN PTLVLSFFTCFSAGGYIGELVLPLSSLLIALLSCILSIMLVVLLHIFVLVPLSSAEES LAYREDDLRGRLGKVITAVPVDGFGEVVIEGIGGTISKSAVSFDNQQISYGTTVLVVD INNGVLSVTPHEPI*" gene complement(3047613..3048137) /gene="nfeDB" /locus_tag="BSU_31020" /old_locus_tag="BSU31020" promotor_-10 complement(3048181..3048196) /Source="Nicolas_upshift_promotors" /id="U2403" /multdbtbs="SigW" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1691 /SigmaFactorBS="acttcaaatgggttatttgtcttaaaatttTGAAACTTTTcc cgaggtgtcTCGTATAAATGGTAACggcagccgttcatcaatgcattgatgaagaaag g" /listShort="yuaF, yuaG, yuaI, S1182" /listLong="S1181" /label="promotor_-10" upshifts complement(3048187) /Source="Nicolas_upshifts" /id="U2403" /multdbtbs="SigW" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1691 /SigmaFactorBS="acttcaaatgggttatttgtcttaaaatttTGAAACTTTTcc cgaggtgtcTCGTATAAATGGTAACggcagccgttcatcaatgcattgatgaagaaag g" /listShort="yuaF, yuaG, yuaI, S1182" /listLong="S1181" S_feature complement(3048189..3048276) /Source="Nicolas_S_feature" /locus_tag="new_3182591_3182678_c" /HighExp="S4, S8, S6, S7, S5, S3, B36, LoTm, B60, Pyr" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigEF" /TUshortPSig="0.96" /TUlongSig="NA" /TUlongPSig="NA" /label="S1183" promotor_-35 complement(3048208..3048217) /Source="Nicolas_upshift_promotors" /id="U2403" /multdbtbs="SigW" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1691 /SigmaFactorBS="acttcaaatgggttatttgtcttaaaatttTGAAACTTTTcc cgaggtgtcTCGTATAAATGGTAACggcagccgttcatcaatgcattgatgaagaaag g" /listShort="yuaF, yuaG, yuaI, S1182" /listLong="S1181" /label="promotor_-35" promotor_-10 complement(3048261..3048279) /Source="Nicolas_upshift_promotors" /id="U2405" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.96003996003996" /psig="0.96003996003996" /xcortree=1070 /SigmaFactorBS="gtttctaatctggcttcattaaagatactcatcatatCTCCT CctaaaatgacattaCCATATATATAAGCAATTAtcatttataaagcacttcaaatgg g" /listShort="S1183, yuaF, yuaG, yuaI" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3048271 /Source="Nicolas_upshifts" /id="U2404" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.442557442557443" /psig="0.962037962037962" /xcortree=633 /SigmaFactorBS="agtttcaaaattttaagacaaataacccatttgaagtgcttt ataaatgataattgcttatataTATGGTAATGTCATTTTAGGaggagatatgatgagt a" /listShort="yuaE, S1184" /GFF_Attribute="listLong" misc_feature 3048275..3048294 /Source="Nicolas_upshift_promotors" /id="U2404" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.442557442557443" /psig="0.962037962037962" /xcortree=633 /SigmaFactorBS="agtttcaaaattttaagacaaataacccatttgaagtgcttt ataaatgataattgcttatataTATGGTAATGTCATTTTAGGaggagatatgatgagt a" /listShort="yuaE, S1184" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(3048276) /Source="Nicolas_upshifts" /id="U2405" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.96003996003996" /psig="0.96003996003996" /xcortree=1070 /SigmaFactorBS="gtttctaatctggcttcattaaagatactcatcatatCTCCT CctaaaatgacattaCCATATATATAAGCAATTAtcatttataaagcacttcaaatgg g" /listShort="S1183, yuaF, yuaG, yuaI" /GFF_Attribute="listLong" promotor_-35 complement(3048294..3048299) /Source="Nicolas_upshift_promotors" /id="U2405" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.96003996003996" /psig="0.96003996003996" /xcortree=1070 /SigmaFactorBS="gtttctaatctggcttcattaaagatactcatcatatCTCCT CctaaaatgacattaCCATATATATAAGCAATTAtcatttataaagcacttcaaatgg g" /listShort="S1183, yuaF, yuaG, yuaI" /GFF_Attribute="listLong" /label="promotor_-35" CDS 3048305..3048793 /gene="yuaE" /locus_tag="BSU_31030" /old_locus_tag="BSU31030" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_390981.1" /db_xref="EnsemblGenomes-Gn:BSU31030" /db_xref="EnsemblGenomes-Tr:CAB15081" /db_xref="InterPro:IPR024775" /db_xref="InterPro:IPR034660" /db_xref="SubtiList:BG13945" /db_xref="UniProtKB/Swiss-Prot:O32078" /translation="MSIFNEARLETWNELKGLSDEKLNQKPSAEEWSIREVLDHLKKI DMTAQKMLKERVKDAPIKEIEEKPLEVAQDRNNKRKAPSHLEPAHDFISGSQMKRELD VVREQLTAAIASLKEEDFERVLPHPVFQELTVRQWIDFIGHHEKRHLSQMKEIKEKIE RA*" gene 3048305..3048793 /gene="yuaE" /locus_tag="BSU_31030" /old_locus_tag="BSU31030" downshifts 3048770 /Source="Nicolas_upshifts" /id="D1600" /incds=0 /nref=205 /ntot=267 /MaxReadThrough="4.05856" /MaxDrop="6.05192" /score="-4.20632485" /energy="-15" /TU="U2404" /idTUdmin="U2404" /TUdmin="-354" /isTUend="FALSE" CDS complement(3048799..3049377) /gene="yuaD" /locus_tag="BSU_31040" /old_locus_tag="BSU31040" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 11886751" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_390982.1" /db_xref="EnsemblGenomes-Gn:BSU31040" /db_xref="EnsemblGenomes-Tr:CAB15082" /db_xref="GOA:O32079" /db_xref="InterPro:IPR005302" /db_xref="InterPro:IPR011037" /db_xref="PDB:1ORU" /db_xref="SubtiList:BG13944" /db_xref="UniProtKB/Swiss-Prot:O32079" /translation="MWKRMTAKAEGLYIADTKSFVTKQMDKLDFDYGGIPGDLHFGLT KKAGAREPMFSRGTEIFNRRQISIVSIEECNEIALKMGVPRILPEWLGANVAVSGMPD LTSLKEGSRIIFPSGAALLCEGENDPCIQPGEVIQSYYPDQPKLASAFVRHALGIRGI VCIVERPGAVYTGDEIEVHSYQRKVKRKAERV*" gene complement(3048799..3049377) /gene="yuaD" /locus_tag="BSU_31040" /old_locus_tag="BSU31040" S_feature 3048815..3049206 /Source="Nicolas_S_feature" /locus_tag="new_3183217_3183608" /HighExp="Etha, S8, LPhT, S6, Salt, LoTm, S5, H2O2, S7, dia5" /AntisenseName="yuaD" /AntisenseCor="-0.48344313728748101" /AntisenseRegPval="-16.399999999999999" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.962" /TUlongSig="NA" /TUlongPSig="NA" /label="S1184" downshifts complement(3048826) /Source="Nicolas_upshifts" /id="D1601" /incds=0 /nref=87 /ntot=222 /MaxReadThrough="0.58189" /MaxDrop="3.9885" /score="0.718873117" /energy="-11.5" /TU="NA" /idTUdmin="U2406" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(3049411..3049430) /Source="Nicolas_upshift_promotors" /id="U2406" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.437562437562438" /psig="0.97902097902098" /xcortree=2148 /SigmaFactorBS="gcctaaaacggtataatcaaaatcccgctCCTTTACAgagcg ggatttttTGGGATAATGAAGCATAGGTggaaattttagataagaaggaaggtgccag c" /listShort="yuaD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3049420) /Source="Nicolas_upshifts" /id="U2406" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.437562437562438" /psig="0.97902097902098" /xcortree=2148 /SigmaFactorBS="gcctaaaacggtataatcaaaatcccgctCCTTTACAgagcg ggatttttTGGGATAATGAAGCATAGGTggaaattttagataagaaggaaggtgccag c" /listShort="yuaD" /GFF_Attribute="listLong" promotor_-35 complement(3049444..3049451) /Source="Nicolas_upshift_promotors" /id="U2406" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.437562437562438" /psig="0.97902097902098" /xcortree=2148 /SigmaFactorBS="gcctaaaacggtataatcaaaatcccgctCCTTTACAgagcg ggatttttTGGGATAATGAAGCATAGGTggaaattttagataagaaggaaggtgccag c" /listShort="yuaD" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3049465..3050673) /gene="gbsB" /locus_tag="BSU_31050" /old_locus_tag="BSU31050" /EC_number="1.1.99.1" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:8752328, 22408163" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8752328, 22408163; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="choline dehydrogenase" /protein_id="NP_390983.2" /db_xref="EnsemblGenomes-Gn:BSU31050" /db_xref="EnsemblGenomes-Tr:CAB15083" /db_xref="GOA:P71017" /db_xref="InterPro:IPR001670" /db_xref="InterPro:IPR018211" /db_xref="SubtiList:BG11941" /db_xref="UniProtKB/Swiss-Prot:P71017" /translation="MTLNMKVESMQKFHTFEIPTVIKHGIGAIKHTGEEVAALGVSKA LLVTDPGIYKAGVADPVIESLKEAGIEVVLFNKVEPNPPVRLVNEGSELYKKENCNGL VAVGGGSSMDTAKAIGVEATHEGSVLDYEAADGKKPLENRIPPLTTIPTTAGTGSEVT QWAVITDEEREFKFNTGGPLIAAHLTIIDPELHVSMPPHVTAMTGIDALAHAIECYTM KFAQPITDAVALMAIEYAAHYIKRAFADGEDLEARYGMAQAAMLAGLSYGSESAGAAH AMSQTLGGIIPVAHGQCVAAMMGPVMEYNWKGYPEKFARIAKAFGIDTSKMTTEEAAK ASVNWMYDLVEDLEVPTLEEQGVSPDMIERLSKEAMKDPQTFGNPRDLNEKAYNWIYK RCFNLTPKTV*" gene complement(3049465..3050673) /gene="gbsB" /locus_tag="BSU_31050" /old_locus_tag="BSU31050" downshifts complement(3049486) /Source="Nicolas_upshifts" /id="D1602" /incds=0 /nref=2 /ntot=70 /MaxReadThrough="2.9443" /MaxDrop="3.26923" /score="18.315772" /energy="-13.6" /TU="NA" /idTUdmin="U2406" /TUdmin="-660" /isTUend="FALSE" promotor_-10 complement(3050442..3050461) /Source="Nicolas_upshift_promotors" /id="U2407" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.66033966033966" /psig="0.983016983016983" /xcortree=2046 /SigmaFactorBS="aaagccggtgttgctgatcccgtaatcgaatCACTTAAAgaa gcaggcattgaAGTGGTACTCTTTAATAAAGttgagccaaacccgcctgtccgtctgg t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3050454) /Source="Nicolas_upshifts" /id="U2407" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.66033966033966" /psig="0.983016983016983" /xcortree=2046 /SigmaFactorBS="aaagccggtgttgctgatcccgtaatcgaatCACTTAAAgaa gcaggcattgaAGTGGTACTCTTTAATAAAGttgagccaaacccgcctgtccgtctgg t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(3050476..3050483) /Source="Nicolas_upshift_promotors" /id="U2407" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.66033966033966" /psig="0.983016983016983" /xcortree=2046 /SigmaFactorBS="aaagccggtgttgctgatcccgtaatcgaatCACTTAAAgaa gcaggcattgaAGTGGTACTCTTTAATAAAGttgagccaaacccgcctgtccgtctgg t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3050690..3052162) /gene="gbsA" /locus_tag="BSU_31060" /old_locus_tag="BSU31060" /EC_number="1.2.1.8" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:8752328, 9297465, 22408163" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8752328, 9297465, 22408163; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="glycine betaine aldehyde dehydrogenase, NAD+-dependent" /protein_id="NP_390984.1" /db_xref="EnsemblGenomes-Gn:BSU31060" /db_xref="EnsemblGenomes-Tr:CAB15084" /db_xref="GOA:P71016" /db_xref="InterPro:IPR011264" /db_xref="InterPro:IPR015590" /db_xref="InterPro:IPR016160" /db_xref="InterPro:IPR016161" /db_xref="InterPro:IPR016162" /db_xref="InterPro:IPR029510" /db_xref="SubtiList:BG11940" /db_xref="UniProtKB/Swiss-Prot:P71016" /translation="MSQTLFIDGEWISAEKEQIRSIINPFNQEEIATVSEGGREDAIK AIAAARRAFDKGEWSSLSGLERGKIVLKIAELIRRDLEELAELESLDTGKTLEESKAD MDDIANVFQYYAGLADKDGGEIISSPIPDSESKIIREPIGVCGQITPWNYPLLQASWK IAPALAAGNTIVMKPSEITPLTTIKVFKLMEEAGVPKGVANLVLGPGATVGDELAVNK DVDLISFTGGIETGKKIMRAASGNVKKIALELGGKNPNIVFKDADLEVAVDQALNAVF FHAGQVCSAGSRLLVEDAIHDQFLAELVKRAKRIKLGNGFHAETESGPLISAEHRAKV EKYVEIGIEEGAKLETGGKRPEDPELQNGFFYEPTIFSNCNSDMRIVQEEVFGPVLTV ETFSSEEEVIELANDTIYGLAGAVWSKDIEKCERVAARLRMGTVWINDFHPYFAQAPW GGYKQSGFGRELGKIGLEEYTEVKHVYRNTKPAAVNWFNS*" gene complement(3050690..3052162) /gene="gbsA" /locus_tag="BSU_31060" /old_locus_tag="BSU31060" promotor_-10 complement(3052213..3052232) /Source="Nicolas_upshift_promotors" /id="U2408" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.8001998001998" /psig="0.999000999001" /xcortree=3079 /SigmaFactorBS="aaagaaaaatcaaaatgggaCTTTGACAgtttaaaaaccata TGTTAGATTAAGGTTGTTAAaaacattaaatttttatttaacaaactttatttacgtc a" /listShort="gbsA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3052214) /Source="Nicolas_upshifts" /id="U2408" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.8001998001998" /psig="0.999000999001" /xcortree=3079 /SigmaFactorBS="aaagaaaaatcaaaatgggaCTTTGACAgtttaaaaaccata TGTTAGATTAAGGTTGTTAAaaacattaaatttttatttaacaaactttatttacgtc a" /listShort="gbsA" /GFF_Attribute="listLong" promotor_-35 complement(3052247..3052254) /Source="Nicolas_upshift_promotors" /id="U2408" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.8001998001998" /psig="0.999000999001" /xcortree=3079 /SigmaFactorBS="aaagaaaaatcaaaatgggaCTTTGACAgtttaaaaaccata TGTTAGATTAAGGTTGTTAAaaacattaaatttttatttaacaaactttatttacgtc a" /listShort="gbsA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 3052274..3052280 /Source="Nicolas_upshift_promotors" /id="U2409" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.318681318681319" /psig="0.988011988011988" /xcortree=2369 /SigmaFactorBS="tcaaagtcccattttgatttttcttTTTGACTtttcctcatg tttCGTTAAGATAAAGAACATAAagaaataacttaacgaatttaattttctaaaggaa a" /listShort="yuaC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3052294..3052313 /Source="Nicolas_upshift_promotors" /id="U2409" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.318681318681319" /psig="0.988011988011988" /xcortree=2369 /SigmaFactorBS="tcaaagtcccattttgatttttcttTTTGACTtttcctcatg tttCGTTAAGATAAAGAACATAAagaaataacttaacgaatttaattttctaaaggaa a" /listShort="yuaC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3052309 /Source="Nicolas_upshifts" /id="U2409" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.318681318681319" /psig="0.988011988011988" /xcortree=2369 /SigmaFactorBS="tcaaagtcccattttgatttttcttTTTGACTtttcctcatg tttCGTTAAGATAAAGAACATAAagaaataacttaacgaatttaattttctaaaggaa a" /listShort="yuaC" /GFF_Attribute="listLong" CDS 3052361..3052903 /gene="gbsR" /locus_tag="BSU_31070" /old_locus_tag="BSU31070" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:8752328, 22408163" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8752328, 22408163; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional repressor for gbsAB" /protein_id="NP_390985.1" /db_xref="EnsemblGenomes-Gn:BSU31070" /db_xref="EnsemblGenomes-Tr:CAB15085" /db_xref="GOA:P71015" /db_xref="InterPro:IPR026282" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG12342" /db_xref="UniProtKB/Swiss-Prot:P71015" /translation="MDENPEFAAIEQARDLVIDSIAETMDLYGITRSVGILYGTMYMR DEMTLDEMREELQMSKPSMSTGVKKLQDLNVVKKTFHRGIRKHTFVAEKDFFKFFTNF FPPKWEREVQVNVTAIEEAQADLQKVLCKEDLDEDIKNEALQLYDQLESSKAYYDWLK RLAESVQTGEIFKFIPVETK*" gene 3052361..3052903 /gene="gbsR" /locus_tag="BSU_31070" /old_locus_tag="BSU31070" downshifts 3052886 /Source="Nicolas_upshifts" /id="D1603" /incds=0 /nref=74 /ntot=220 /MaxReadThrough="1.70461" /MaxDrop="3.5918" /score="26.1509691" /energy="-9.9" /TU="NA" /idTUdmin="U2409" /TUdmin=0 /isTUend="TRUE" promotor_-35 3052980..3052987 /Source="Nicolas_upshift_promotors" /id="U2410" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.657342657342657" /psig="0.999000999001" /xcortree=3240 /SigmaFactorBS="tgtaactactacaaatttgaaaaatacgggaaaaacacccCA TTTACTtccaaaatatttgaTGGTAATTTTATGTAGGTAAaatttgtatttggccttt c" /listShort="S1185, yuaB" /GFF_Attribute="listLong" /label="promotor_-35" S_feature 3053000..3053100 /Source="Nicolas_S_feature" /locus_tag="new_3187402_3187502" /HighExp="BT, S0, BI, T-1.10H, T-1.40H, T1.0H, T-0.40H, T0.0H, S2, T-2.40H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S1185" upshifts 3053000 /Source="Nicolas_upshifts" /id="U2410" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.657342657342657" /psig="0.999000999001" /xcortree=3240 /SigmaFactorBS="tgtaactactacaaatttgaaaaatacgggaaaaacacccCA TTTACTtccaaaatatttgaTGGTAATTTTATGTAGGTAAaatttgtatttggccttt c" /listShort="S1185, yuaB" /GFF_Attribute="listLong" promotor_-10 3053002..3053021 /Source="Nicolas_upshift_promotors" /id="U2410" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.657342657342657" /psig="0.999000999001" /xcortree=3240 /SigmaFactorBS="tgtaactactacaaatttgaaaaatacgggaaaaacacccCA TTTACTtccaaaatatttgaTGGTAATTTTATGTAGGTAAaatttgtatttggccttt c" /listShort="S1185, yuaB" /GFF_Attribute="listLong" /label="promotor_-10" CDS 3053101..3053646 /gene="bslA" /locus_tag="BSU_31080" /old_locus_tag="BSU31080" /function="15.3: Cell adhesion" /experiment="publication(s) with functional evidences, PMID:21097620, 21742882, 22571672, 23904481, 28698374, 28701036, 28751732" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 21097620, 21742882, 22571672, 23904481, 28698374, 28701036, 28751732; Product type s: structure" /codon_start=1 /transl_table=11 /product="biofilm hydrophobic layer component" /protein_id="NP_390986.1" /db_xref="EnsemblGenomes-Gn:BSU31080" /db_xref="EnsemblGenomes-Tr:CAB15086" /db_xref="GOA:P71014" /db_xref="InterPro:IPR034650" /db_xref="PDB:4BHU" /db_xref="SubtiList:BG12341" /db_xref="UniProtKB/Swiss-Prot:P71014" /translation="MKRKLLSSLAISALSLGLLVSAPTASFAAESTSTKAHTESTMRT QSTASLFATITGASKTEWSFSDIELTYRPNTLLSLGVMEFTLPSGFTANTKDTLNGNA LRTTQILNNGKTVRVPLALDLLGAGEFKLKLNNKTLPAAGTYTFRAENKSLSIGNKFY AEASIDVAKRSTPPTQPCGCN*" gene 3053101..3053646 /gene="bslA" /locus_tag="BSU_31080" /old_locus_tag="BSU31080" downshifts 3053633 /Source="Nicolas_upshifts" /id="D1604" /incds=0 /nref=109 /ntot=219 /MaxReadThrough="0.85027" /MaxDrop="6.00835" /score="20.8976757" /energy="-10.2" /TU="NA" /idTUdmin="U2410" /TUdmin="-1" /isTUend="TRUE" promotor_-35 3053738..3053745 /Source="Nicolas_upshift_promotors" /id="U2411" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.796203796203796" /psig="0.997002997002997" /xcortree=2704 /SigmaFactorBS="ccccgttatcttttttctggtttaaaatttaaATTGACAAac actagaaacagGAGTAAATTCTTGAGTGTTCaatttcatacagtctcttttaccgctt a" /listShort="NA, ktrA, ktrB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3053759..3053778 /Source="Nicolas_upshift_promotors" /id="U2411" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.796203796203796" /psig="0.997002997002997" /xcortree=2704 /SigmaFactorBS="ccccgttatcttttttctggtttaaaatttaaATTGACAAac actagaaacagGAGTAAATTCTTGAGTGTTCaatttcatacagtctcttttaccgctt a" /listShort="NA, ktrA, ktrB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3053766 /Source="Nicolas_upshifts" /id="U2411" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.796203796203796" /psig="0.997002997002997" /xcortree=2704 /SigmaFactorBS="ccccgttatcttttttctggtttaaaatttaaATTGACAAac actagaaacagGAGTAAATTCTTGAGTGTTCaatttcatacagtctcttttaccgctt a" /listShort="NA, ktrA, ktrB" /GFF_Attribute="listLong" misc_RNA 3053771..3053939 /gene="swdA" /locus_tag="BSU_misc_RNA_52" /product="cyclic-di-AMP-sensing riboswitch" /experiment="publication(s) with functional evidences, PMID:20511502, 23086297, 24141192, 25086507, 25086509, 26789423, 28420751" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 20511502, 23086297, 24141192, 25086507, 25086509, 26789423, 28420751; Product type n: RNA" gene 3053771..3053939 /gene="swdA" /locus_tag="BSU_misc_RNA_52" downshifts 3053920 /Source="Nicolas_upshifts" /id="D1605" /incds=0 /nref=16 /ntot=104 /MaxReadThrough="6.04086" /MaxDrop="4.75274" /score="3.29445061" /energy="-6.1" /TU="U2411" /idTUdmin="U2410" /TUdmin=286 /isTUend="FALSE" CDS 3054012..3054680 /gene="ktrA" /locus_tag="BSU_31090" /old_locus_tag="BSU31090" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:12562800, 15096624, 23598340, 23671116, 25957408, 26771197" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12562800, 15096624, 23598340, 23671116, 25957408, 26771197; Product type t : transporter" /codon_start=1 /transl_table=11 /product="potassium uptake protein" /protein_id="NP_390987.1" /db_xref="EnsemblGenomes-Gn:BSU31090" /db_xref="EnsemblGenomes-Tr:CAB15087" /db_xref="GOA:O32080" /db_xref="InterPro:IPR003148" /db_xref="InterPro:IPR006037" /db_xref="InterPro:IPR036291" /db_xref="InterPro:IPR036721" /db_xref="PDB:1LSU" /db_xref="PDB:2HMS" /db_xref="PDB:2HMT" /db_xref="PDB:2HMU" /db_xref="PDB:2HMV" /db_xref="PDB:2HMW" /db_xref="PDB:4J7C" /db_xref="PDB:4J90" /db_xref="PDB:4J91" /db_xref="PDB:5BUT" /db_xref="SubtiList:BG13943" /db_xref="UniProtKB/Swiss-Prot:O32080" /translation="MGRIKNKQFAVIGLGRFGGSICKELHRMGHEVLAVDINEEKVNA YASYATHAVIANATEENELLSLGIRNFEYVIVAIGANIQASTLTTLLLKELDIPNIWV KAQNYYHHKVLEKIGADRIIHPEKDMGVKIAQSLSDENVLNYIDLSDEYSIVELLATR KLDSKSIIDLNVRAKYGCTILAIKHHGDICLSPAPEDIIREQDCLVIMGHKKDIKRFE NEGM*" gene 3054012..3054680 /gene="ktrA" /locus_tag="BSU_31090" /old_locus_tag="BSU31090" CDS 3054687..3056024 /gene="ktrB" /locus_tag="BSU_31100" /old_locus_tag="BSU31100" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:12562800, 15096624, 15849754, 16850406, 17932047, 23598340, 26771197, 28783096, 28825218" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12562800, 15096624, 15849754, 16850406, 17932047, 23598340, 26771197, 28783096, 28825218; Product type t: transporter" /codon_start=1 /transl_table=11 /product="potassium transporter ATPase" /protein_id="NP_390988.1" /db_xref="EnsemblGenomes-Gn:BSU31100" /db_xref="EnsemblGenomes-Tr:CAB15088" /db_xref="GOA:O32081" /db_xref="InterPro:IPR003445" /db_xref="InterPro:IPR004772" /db_xref="PDB:4J7C" /db_xref="PDB:5BUT" /db_xref="SubtiList:BG13956" /db_xref="UniProtKB/Swiss-Prot:O32081" /translation="MTLQKDKVIKWVRFTPPQVLAIGFFLTIIIGAVLLMLPISTTKP LSWIDALFTAASATTVTGLAVVDTGTQFTVFGQTVIMGLIQIGGLGFMTFAVLIVMIL GKKIGLKERMLVQEALNQPTIGGVIGLVKVLFLFSISIELIAALILSIRLVPQYGWSS GLFASLFHAISAFNNAGFSLWPDNLMSYVGDPTVNLVITFLFITGGIGFTVLFDVMKN RRFKTFSLHTKLMLTGTLMLNAIAMLTVFILEYSNPGTLGHLHIVDKLWASYFQAVTP RTAGFNSLDFGSMREGTIVFTLLLMFIGAGSASTASGIKLTTFIVILTSVIAYLRGKK ETVIFRRSIKYPIIIKALAVSVTSLFIVFLGIFALTITEQAPFLQIVFETFSAFGTVG LTMGLTPELTTAGKCIIIVIMFIGRIGPLTFVFSFAKTEQSNIRYPDGEVFTG*" gene 3054687..3056024 /gene="ktrB" /locus_tag="BSU_31100" /old_locus_tag="BSU31100" downshifts 3056010 /Source="Nicolas_upshifts" /id="D1606" /incds=0 /nref=9 /ntot=98 /MaxReadThrough="0.86883" /MaxDrop="3.37604" /score="25.8974852" /energy="-11.9" /TU="NA" /idTUdmin="U2411" /TUdmin=0 /isTUend="TRUE" CDS complement(3056060..3056323) /gene="yubF" /locus_tag="BSU_31110" /old_locus_tag="BSU31110" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_390989.1" /db_xref="EnsemblGenomes-Gn:BSU31110" /db_xref="EnsemblGenomes-Tr:CAB15089" /db_xref="GOA:O32082" /db_xref="InterPro:IPR008024" /db_xref="SubtiList:BG13955" /db_xref="UniProtKB/Swiss-Prot:O32082" /translation="MQKYRRRNTVAFTVLAYFTFFAGVFLFSIGLYNADNLELNEKGY YIAVMILVAVGAILTQKVTRDNAEDNEIIAEQEKRQNQSHIES*" gene complement(3056060..3056323) /gene="yubF" /locus_tag="BSU_31110" /old_locus_tag="BSU31110" downshifts complement(3056078) /Source="Nicolas_upshifts" /id="D1607" /incds=0 /nref=237 /ntot=309 /MaxReadThrough="2.4577" /MaxDrop="7.13564" /score="30.2020977" /energy="-11.9" /TU="NA" /idTUdmin="U2412" /TUdmin="-14" /isTUend="TRUE" promotor_-10 complement(3056363..3056382) /Source="Nicolas_upshift_promotors" /id="U2412" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.543456543456543" /psig="0.994005994005994" /xcortree=2705 /SigmaFactorBS="tttactggtatttttaattctttGTTCCATTccggggaattt gAGGTATAATATTCCACGGAAgttatcactttttaactatgctttcgggagggaacaa a" /listShort="yubF" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3056365) /Source="Nicolas_upshifts" /id="U2412" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.543456543456543" /psig="0.994005994005994" /xcortree=2705 /SigmaFactorBS="tttactggtatttttaattctttGTTCCATTccggggaattt gAGGTATAATATTCCACGGAAgttatcactttttaactatgctttcgggagggaacaa a" /listShort="yubF" /GFF_Attribute="listLong" promotor_-35 complement(3056395..3056402) /Source="Nicolas_upshift_promotors" /id="U2412" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.543456543456543" /psig="0.994005994005994" /xcortree=2705 /SigmaFactorBS="tttactggtatttttaattctttGTTCCATTccggggaattt gAGGTATAATATTCCACGGAAgttatcactttttaactatgctttcgggagggaacaa a" /listShort="yubF" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3056432..3057280) /gene="lytG" /locus_tag="BSU_31120" /old_locus_tag="BSU31120" /EC_number="3.2.1.-" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:12525152, 16855244, 28448118, 28811162" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12525152, 16855244, 28448118, 28811162; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="exoglucosaminidase" /protein_id="NP_390990.1" /db_xref="EnsemblGenomes-Gn:BSU31120" /db_xref="EnsemblGenomes-Tr:CAB15090" /db_xref="GOA:O32083" /db_xref="InterPro:IPR002901" /db_xref="InterPro:IPR025987" /db_xref="SubtiList:BG13954" /db_xref="UniProtKB/Swiss-Prot:O32083" /translation="MARKKLKKRKLLISLFFLVSIPLALFVLATTLSKPIEISKETEE IDEQQVFIDSLSGHAQILYEKYHVLPSITIAQAILESDWGNSELAAKANNLFGVKGNY KGHHVTMETDEVEKGKRKTIRAKFRKYSTFFESMDDHAQLFVRGTSWNKKKYKPVLEA GNYKEAATALQTSGYATDPDYADKISAIVEKYDLDEYDEVNPSLKSVDLNASIKDSAV QDVWSKPSTDDRSIRLTSAQSYVGKDIKVVSKKQKGQSVWYQFQINDKLIGWIDDSAV EIKEAT*" gene complement(3056432..3057280) /gene="lytG" /locus_tag="BSU_31120" /old_locus_tag="BSU31120" promotor_-10 complement(3057325..3057344) /Source="Nicolas_upshift_promotors" /id="U2413" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.40959040959041" /psig="0.994005994005994" /xcortree=2525 /SigmaFactorBS="gcaatcttttcccaactttatccctaaagAATTGAAAaatat tagaagtgcAAGTAAAATTCTAAAAGGTAgattcttttacattcgtaatcttttaatt c" /listShort="lytG, yubF" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3057335) /Source="Nicolas_upshifts" /id="U2413" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.40959040959041" /psig="0.994005994005994" /xcortree=2525 /SigmaFactorBS="gcaatcttttcccaactttatccctaaagAATTGAAAaatat tagaagtgcAAGTAAAATTCTAAAAGGTAgattcttttacattcgtaatcttttaatt c" /listShort="lytG, yubF" /GFF_Attribute="listLong" promotor_-35 complement(3057359..3057366) /Source="Nicolas_upshift_promotors" /id="U2413" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.40959040959041" /psig="0.994005994005994" /xcortree=2525 /SigmaFactorBS="gcaatcttttcccaactttatccctaaagAATTGAAAaatat tagaagtgcAAGTAAAATTCTAAAAGGTAgattcttttacattcgtaatcttttaatt c" /listShort="lytG, yubF" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3057441..3058976) /gene="yubD" /locus_tag="BSU_31130" /old_locus_tag="BSU31130" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406, 22720735, 28248504; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative efflux transporter" /protein_id="NP_390991.1" /db_xref="EnsemblGenomes-Gn:BSU31130" /db_xref="EnsemblGenomes-Tr:CAB15091" /db_xref="GOA:O32084" /db_xref="InterPro:IPR011701" /db_xref="InterPro:IPR020846" /db_xref="InterPro:IPR036259" /db_xref="SubtiList:BG13953" /db_xref="UniProtKB/Swiss-Prot:O32084" /translation="MKTKHYWVISLLAVLAVGPGLMSNTALSSVQGLVQKTVGTSVFT SVNPILIGNMAFALLVPAGPLLRKKFGARPVYLASLPVFILGSLLIACSGDIALMAAG RFLQGAATGVMLMIMIPMLVLSFPIERRNYALLVLIGGFYGSVIIGTILGTIATSCGH WRWLFFIFGTLSLIGVAVSYFFLHDEHHGAADQEQPLDRAGILLSVFLAAASAVSFIF LQKWGLSSGYVWIGFGVTLCLLIGLLIVEYKVKNPFISIKLMLLPKPVLGLLIIAAGT ITVAVSLSAFQGLLRQMYDISQEHLILLSLTLLIGVAIAAILSALLYDKVGPGMLGII GGLILVFVNFQWLHIQDRSSLYMFAALFIMLAAGTGLTVAAGLMGAAMGGPLPDLVKR MTAVQFLRLFVYMGVPILIGFFTKKDAARQSGSVQDSMMTAYHDLFFISFILSVLLVC LSFCMNATGMGHKLAHKPHDKAKTAPEKPAVSAQGLSKATVKSYKVINDTEYRNALRN LQK*" gene complement(3057441..3058976) /gene="yubD" /locus_tag="BSU_31130" /old_locus_tag="BSU31130" downshifts complement(3057450) /Source="Nicolas_upshifts" /id="D1608" /incds=0 /nref=45 /ntot=159 /MaxReadThrough="1.39941" /MaxDrop="4.26166" /score="-3.3162201" /energy="-5.7" /TU="NA" /idTUdmin="U2415" /TUdmin=0 /isTUend="TRUE" promotor_no_box 3058634..3058734 /Source="Nicolas_upshift_promotors" /id="U2414" /multdbtbs="-" /comp="M21" /sig="Sig-" /pcomp="0.407592407592408" /psig="0.127872127872128" /xcortree=1469 /SigmaFactorBS="tcagcatgacgcctgttgccgccccttgtaaaaagcgccctg ccgccatcaatgcaatatcgcctgaacatgcgatgagcagtgagcctagtataaagac a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_no_box" upshifts 3058694 /Source="Nicolas_upshifts" /id="U2414" /multdbtbs="-" /comp="M21" /sig="Sig-" /pcomp="0.407592407592408" /psig="0.127872127872128" /xcortree=1469 /SigmaFactorBS="tcagcatgacgcctgttgccgccccttgtaaaaagcgccctg ccgccatcaatgcaatatcgcctgaacatgcgatgagcagtgagcctagtataaagac a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" downshifts 3058760 /Source="Nicolas_upshifts" /id="D1609" /incds=1 /nref=1 /ntot=3 /MaxReadThrough="0.0870599999999992" /MaxDrop="3.19459" /score="-1.6836786" /energy="-10.4" /TU="NA" /idTUdmin="U2416" /TUdmin="-1496" /isTUend="FALSE" S_feature complement(3058977..3059144) /Source="Nicolas_S_feature" /locus_tag="new_3193379_3193546_c" /HighExp="Cold, S8, G180, UNK1, C30, G135, S7, Lbexp, MG 25, MG 15" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.34877900000000001" /TUshortSig="SigA, SigA" /TUshortPSig="1, 0.998" /TUlongSig="NA" /TUlongPSig="NA" /label="S1186" promotor_-10 complement(3059133..3059152) /Source="Nicolas_upshift_promotors" /id="U2415" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.642357642357642" /psig=1 /xcortree=2415 /SigmaFactorBS="agctttctatgttgtgcttgaaatttactcCATTGACAaaac acaatcgattTGAAATAATATTTGATTATAtgctcattcattcacataattataataa a" /listShort="S1186, yubD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3059144) /Source="Nicolas_upshifts" /id="U2415" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.642357642357642" /psig=1 /xcortree=2415 /SigmaFactorBS="agctttctatgttgtgcttgaaatttactcCATTGACAaaac acaatcgattTGAAATAATATTTGATTATAtgctcattcattcacataattataataa a" /listShort="S1186, yubD" /GFF_Attribute="listLong" S_feature complement(3059146..3060023) /Source="Nicolas_S_feature" /locus_tag="new_3193548_3194425_c" /HighExp="G180, Cold, C30, G135, Paraq, Oxctl, S8, G150, H2O2, Heat" /AntisenseName="cdoA" /AntisenseCor="-2.3104546834536201E-2" /AntisenseRegPval="-0.2" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.998" /TUlongSig="NA" /TUlongPSig="NA" /label="S1187" promotor_-35 complement(3059167..3059174) /Source="Nicolas_upshift_promotors" /id="U2415" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.642357642357642" /psig=1 /xcortree=2415 /SigmaFactorBS="agctttctatgttgtgcttgaaatttactcCATTGACAaaac acaatcgattTGAAATAATATTTGATTATAtgctcattcattcacataattataataa a" /listShort="S1186, yubD" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 3059386..3059395 /Source="Nicolas_upshift_promotors" /id="U2416" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1385 /SigmaFactorBS="ttttacccccacatttttttgtgttcactgggcgtttGCCGC CTCTAaattgtatatgggTAAATACCATGAATTAACCTatgaaataccaatgtaaggg a" /listShort="cdoA, S1188" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3059409..3059428 /Source="Nicolas_upshift_promotors" /id="U2416" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1385 /SigmaFactorBS="ttttacccccacatttttttgtgttcactgggcgtttGCCGC CTCTAaattgtatatgggTAAATACCATGAATTAACCTatgaaataccaatgtaaggg a" /listShort="cdoA, S1188" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3059409 /Source="Nicolas_upshifts" /id="U2416" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1385 /SigmaFactorBS="ttttacccccacatttttttgtgttcactgggcgtttGCCGC CTCTAaattgtatatgggTAAATACCATGAATTAACCTatgaaataccaatgtaaggg a" /listShort="cdoA, S1188" /GFF_Attribute="listLong" CDS 3059461..3059946 /gene="cdoA" /locus_tag="BSU_31140" /old_locus_tag="BSU31140" /EC_number="1.13.11.20" /function="16.11: Scavenge (Catabolism)" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:10939241, 15699190, 16855246, 25307852, 26590284" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10939241, 15699190, 16855246, 25307852, 26590284; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="cysteine dioxygenase" /protein_id="NP_390992.1" /db_xref="EnsemblGenomes-Gn:BSU31140" /db_xref="EnsemblGenomes-Tr:CAB15092" /db_xref="GOA:O32085" /db_xref="InterPro:IPR010300" /db_xref="InterPro:IPR011051" /db_xref="InterPro:IPR014710" /db_xref="PDB:3EQE" /db_xref="PDB:4QM8" /db_xref="PDB:4QM9" /db_xref="SubtiList:BG13952" /db_xref="UniProtKB/Swiss-Prot:O32085" /translation="MELYECIQDIFGGLKNPSVKDLATSLKQIPNAAKLSQPYIKEPD QYAYGRNAIYRNNELEIIVINIPPNKETTVHDHGQSIGCAMVLEGKLLNSIYRSTGEH AELSNSYFVHEGECLISTKGLIHKMSNPTSERMVSLHVYSPPLEDMTVFEEQKEVLEN S*" gene 3059461..3059946 /gene="cdoA" /locus_tag="BSU_31140" /old_locus_tag="BSU31140" S_feature 3059947..3060233 /Source="Nicolas_S_feature" /locus_tag="new_3194349_3194635" /HighExp="S6, S8, S7, BT, S5, G/S, C30, Pyr, C90, Glucon" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.53171800000000002" /TUshortSig="SigK" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1188" tRNA complement(3060053..3060125) /gene="trnSL-Ala1" /locus_tag="BSU_tRNA_86" /product="tRNA-Ala" /inference="profile:tRNAscan:1.23" /note="transfer RNA-Ala (GGC); Evidence 2a: Function from experimental evidences in other organisms; Product type n: RNA" gene complement(3060053..3060125) /gene="trnSL-Ala1" /locus_tag="BSU_tRNA_86" downshifts complement(3060068) /Source="Nicolas_upshifts" /id="D1610" /incds=0 /nref=37 /ntot=180 /MaxReadThrough="3.88031" /MaxDrop="4.38957" /score="19.7542652" /energy="-6.2" /TU="U2417" /idTUdmin="U2419" /TUdmin=154 /isTUend="FALSE" downshifts complement(3060112) /Source="Nicolas_upshifts" /id="D1611" /incds=0 /nref=1 /ntot=11 /MaxReadThrough="5.34085" /MaxDrop="4.19639" /score="19.7542652" /energy="-6.2" /TU="U2417" /idTUdmin="U2419" /TUdmin=110 /isTUend="FALSE" promotor_-10 complement(3060136..3060155) /Source="Nicolas_upshift_promotors" /id="U2417" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.96003996003996" /psig="0.998001998001998" /xcortree=1471 /SigmaFactorBS="cttttccgagccttattttttctgtcaattcaagaggaaaca gCTTGtttttcaaaataaaATCATCTATAATAAACATGAcgttacatacggggccata g" /listShort="trnSL-Ala1, S1187, S1186, yubD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3060156) /Source="Nicolas_upshifts" /id="U2417" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.96003996003996" /psig="0.998001998001998" /xcortree=1471 /SigmaFactorBS="cttttccgagccttattttttctgtcaattcaagaggaaaca gCTTGtttttcaaaataaaATCATCTATAATAAACATGAcgttacatacggggccata g" /listShort="trnSL-Ala1, S1187, S1186, yubD" /GFF_Attribute="listLong" promotor_-35 complement(3060170..3060173) /Source="Nicolas_upshift_promotors" /id="U2417" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.96003996003996" /psig="0.998001998001998" /xcortree=1471 /SigmaFactorBS="cttttccgagccttattttttctgtcaattcaagaggaaaca gCTTGtttttcaaaataaaATCATCTATAATAAACATGAcgttacatacggggccata g" /listShort="trnSL-Ala1, S1187, S1186, yubD" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 3060190 /Source="Nicolas_upshifts" /id="D1612" /incds=0 /nref=2 /ntot=13 /MaxReadThrough="3.04964" /MaxDrop="3.22361" /score="-1.6836786" /energy="-10.4" /TU="U2416" /idTUdmin="U2416" /TUdmin="-66" /isTUend="FALSE" CDS complement(3060233..3061063) /gene="uppP" /locus_tag="BSU_31150" /old_locus_tag="BSU31150" /EC_number="3.6.1.27" /function="16.13: Shape" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:15138271, 15849754, 16850406, 27528508, 27578312" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15138271, 15849754, 16850406, 27528508, 27578312; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="undecaprenyl-pyrophosphate phosphatase" /protein_id="NP_390993.1" /db_xref="EnsemblGenomes-Gn:BSU31150" /db_xref="EnsemblGenomes-Tr:CAB15093" /db_xref="GOA:P94507" /db_xref="InterPro:IPR003824" /db_xref="SubtiList:BG13951" /db_xref="UniProtKB/Swiss-Prot:P94507" /translation="MTLWELFVAAILGIVEGLTEYAPVSSTGHMIIVDDIWLKSSNLM SEEAANSFKVVIQLGSILAVAIVFKDRILNLLGLKKNITSDQEQGHKLSIAQIAVGLV PAAVLGFLFEDYIDEYLFSVKTVAIGLIAGAILMLFADWVNKRKTATDTLDRISYKQA IAVGLFQCLSLWPGFSRSGSTISGGVILGLNHRAAADFTFIMAMPIMMGASFLSLVKH WDSLSSDLMPFFIVGFICAFVVALFVVRFFLRLINKIKLVPFAIYRIILGVILLLIMM *" gene complement(3060233..3061063) /gene="uppP" /locus_tag="BSU_31150" /old_locus_tag="BSU31150" downshifts complement(3060244) /Source="Nicolas_upshifts" /id="D1613" /incds=0 /nref=60 /ntot=208 /MaxReadThrough="3.0552" /MaxDrop="5.61932" /score="-4.25033697" /energy="-6.7" /TU="U2419" /idTUdmin="U2419" /TUdmin="-22" /isTUend="TRUE" S_feature complement(3061064..3061155) /Source="Nicolas_S_feature" /locus_tag="new_3195466_3195557_c" /HighExp="dia15, H2O2, Salt, Etha, dia5, LBGtran, M0t90, Lbstat, Mt0, Cold" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1189" CDS complement(3061156..3062322) /gene="yubA" /locus_tag="BSU_31160" /old_locus_tag="BSU31160" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16385049, 16850406; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative integral membrane protein" /protein_id="NP_390994.1" /db_xref="EnsemblGenomes-Gn:BSU31160" /db_xref="EnsemblGenomes-Tr:CAB15094" /db_xref="GOA:O32086" /db_xref="InterPro:IPR002549" /db_xref="SubtiList:BG13950" /db_xref="UniProtKB/Swiss-Prot:O32086" /translation="METLQTWSGRFKRFFLDNKFVLFLLVLLLIGLNILVFTKTSFIF TPIIVLLKTISLPIILTGIVFYLLNPVVDFLERRRIRRIYSILLLYLLVIGLITITIV SIIPFLKEQIMSLIDNIPRYVDVVENQTKQLIGSNFVNQAQQTMNINISDLATKVSDQ AATIVNSTFTGVGNFIGALTEIIISIVTVPFILFYLLKDGRKLPVYILKFVPTRLKEQ TYTVLSEMNHRLSSYIRGQIIVSFCIGFLLFIGYLIIGLDYASLLAVIAACTSIVPYL GPTIAITPAIIIAIVTSPLMLLKLVIVWTIVQLIEGKLISPQIMGKNLHIHPITIIFL LLTAGKLFGVVGIILAIPGYAVAKVITTHLFDWFKMQSHLYDEEKNENTPGHKV*" gene complement(3061156..3062322) /gene="yubA" /locus_tag="BSU_31160" /old_locus_tag="BSU31160" promotor_-35 3062318..3062322 /Source="Nicolas_upshift_promotors" /id="U2418" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.926073926073926" /psig="0.04995004995005" /xcortree=303 /SigmaFactorBS="gcttgaatctgccgctccatgtttgcaacgtcTCCACtatcg ttCCTCCGTCATACATAgtttaattaaattgtacactatcgtccctataatgaaaaat a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3062330..3062344 /Source="Nicolas_upshift_promotors" /id="U2418" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.926073926073926" /psig="0.04995004995005" /xcortree=303 /SigmaFactorBS="gcttgaatctgccgctccatgtttgcaacgtcTCCACtatcg ttCCTCCGTCATACATAgtttaattaaattgtacactatcgtccctataatgaaaaat a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-10 complement(3062346..3062365) /Source="Nicolas_upshift_promotors" /id="U2419" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.706293706293706" /psig=1 /xcortree=1913 /SigmaFactorBS="gttaaaaccgagaaagcttttccagcaattaacggttttTAT TTTTCattatagggacgaTAGTGTACAATTTAATTAAActatgtatgacggaggaacg a" /listShort="yubA, S1189, uppP" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3062346 /Source="Nicolas_upshifts" /id="U2418" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.926073926073926" /psig="0.04995004995005" /xcortree=303 /SigmaFactorBS="gcttgaatctgccgctccatgtttgcaacgtcTCCACtatcg ttCCTCCGTCATACATAgtttaattaaattgtacactatcgtccctataatgaaaaat a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" upshifts complement(3062365) /Source="Nicolas_upshifts" /id="U2419" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.706293706293706" /psig=1 /xcortree=1913 /SigmaFactorBS="gttaaaaccgagaaagcttttccagcaattaacggttttTAT TTTTCattatagggacgaTAGTGTACAATTTAATTAAActatgtatgacggaggaacg a" /listShort="yubA, S1189, uppP" /GFF_Attribute="listLong" promotor_-35 complement(3062379..3062386) /Source="Nicolas_upshift_promotors" /id="U2419" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.706293706293706" /psig=1 /xcortree=1913 /SigmaFactorBS="gttaaaaccgagaaagcttttccagcaattaacggttttTAT TTTTCattatagggacgaTAGTGTACAATTTAATTAAActatgtatgacggaggaacg a" /listShort="yubA, S1189, uppP" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 3062444..3062451 /Source="Nicolas_upshift_promotors" /id="U2420" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.79020979020979" /psig=1 /xcortree=2346 /SigmaFactorBS="attgctggaaaagctttctcggttttaacattctatttatat ctatcATGTGATTttgttcttttTAAGCTATAATTTAGCTATAtcatgcaaaaggagc g" /listShort="yulF" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 3062457 /Source="Nicolas_upshifts" /id="U2420" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.79020979020979" /psig=1 /xcortree=2346 /SigmaFactorBS="attgctggaaaagctttctcggttttaacattctatttatat ctatcATGTGATTttgttcttttTAAGCTATAATTTAGCTATAtcatgcaaaaggagc g" /listShort="yulF" /GFF_Attribute="listLong" promotor_-10 3062462..3062481 /Source="Nicolas_upshift_promotors" /id="U2420" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.79020979020979" /psig=1 /xcortree=2346 /SigmaFactorBS="attgctggaaaagctttctcggttttaacattctatttatat ctatcATGTGATTttgttcttttTAAGCTATAATTTAGCTATAtcatgcaaaaggagc g" /listShort="yulF" /GFF_Attribute="listLong" /label="promotor_-10" CDS 3062504..3063490 /gene="iolU" /locus_tag="BSU_31170" /old_locus_tag="BSU31170" /EC_number="1.1.1.371" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:12450853, 28043209" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12450853, 28043209; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="scyllo-inositol dehydrogenase (NADP+-dependent);biofilm formation" /protein_id="NP_390995.1" /db_xref="EnsemblGenomes-Gn:BSU31170" /db_xref="EnsemblGenomes-Tr:CAB15095" /db_xref="GOA:O05265" /db_xref="InterPro:IPR000683" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG12388" /db_xref="UniProtKB/Swiss-Prot:O05265" /translation="MIRFAIIGTNWITDRFLESAADIEDFQLTAVYSRSAERAGEFAA KHNAAHAFSDLQEMAASDCFDAVYIASPNALHKEQAVLFMNHGKHVLCEKPFASNTKE TEEMISAAKANGVVLMEAMKTTFLPNFKELKKHLHKIGTVRRFTASYCQYSSRYDAFR SGTVLNAFQPELSNGSLMDIGVYCIYPAVVLFGAPKDVKANGYALSSGVDGEGTVILS YDGFEAVLMHSKISTSYAPAEIQGEDGTIVIDTIHRPERVEIRYRDGRLENIAIPDPK PAMFYEAEEFVTLIKENKLESEENTFERSLTTAKIMEEARKQMGIVYPADQA*" gene 3062504..3063490 /gene="iolU" /locus_tag="BSU_31170" /old_locus_tag="BSU31170" downshifts 3063461 /Source="Nicolas_upshifts" /id="D1614" /incds=0 /nref=30 /ntot=279 /MaxReadThrough="1.83109" /MaxDrop="4.96985" /score="21.8997198" /energy="-15.1" /TU="NA" /idTUdmin="U2420" /TUdmin="-7" /isTUend="TRUE" CDS complement(3063531..3064805) /gene="rhaA" /locus_tag="BSU_31180" /old_locus_tag="BSU31180" /EC_number="5.3.1.14" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:10960106, 26712933" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10960106, 26712933; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="L-rhamnose isomerase" /protein_id="NP_390996.1" /db_xref="EnsemblGenomes-Gn:BSU31180" /db_xref="EnsemblGenomes-Tr:CAB15096" /db_xref="GOA:O05264" /db_xref="InterPro:IPR009308" /db_xref="InterPro:IPR036237" /db_xref="SubtiList:BG12387" /db_xref="UniProtKB/Swiss-Prot:O05264" /translation="MTIKANYDSAKQAYEKWGIDVEEALRQLEQVPISIHCWQGDDIE GFEVNKGELSGGIDVTGNYPGKAQTPEELRRDLEKALSLIPGKHRVNLHAIYAETNRE AVERDELKPQHFENWVKWAKNLGLGLDFNPTLFSHEKAADGLTLSHPDPDIREFWIRH CIACRRIGEYFGKELGTPCLTNIWIPDGYKDIPSDRLTPRKRLKESLDRIFSEEISEQ HNLDSIESKLFGLGSESYVVGSHEFYLAYALTNHKLCLLDTGHFHPTETVSNKISSML LYTDKLALHVSRPVRWDSDHVVVLDDELREIALEIVRNHALEKVAIGLDFFDASINRV AAWTIGTRNMIKALLYALLLPNGYLKQLQEEGRYTERLALMEEFKTYPFGAIWDSYCE QMGVPVKEAWLYDIKEYEQQVLLKRKASSPIV*" gene complement(3063531..3064805) /gene="rhaA" /locus_tag="BSU_31180" /old_locus_tag="BSU31180" downshifts complement(3063544) /Source="Nicolas_upshifts" /id="D1615" /incds=0 /nref=3 /ntot=29 /MaxReadThrough="0.802" /MaxDrop="4.45322" /score="14.0829844" /energy="-12.6" /TU="NA" /idTUdmin="U2421" /TUdmin=242 /isTUend="FALSE" CDS complement(3064831..3065145) /gene="rhaM" /locus_tag="BSU_31190" /old_locus_tag="BSU31190" /EC_number="5.1.3.32" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:15576793, 15876375, 26712933" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15576793, 15876375, 26712933; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="L-rhamnose mutarotase" /protein_id="NP_390997.1" /db_xref="EnsemblGenomes-Gn:BSU31190" /db_xref="EnsemblGenomes-Tr:CAB15097" /db_xref="GOA:O05263" /db_xref="InterPro:IPR008000" /db_xref="InterPro:IPR011008" /db_xref="InterPro:IPR013448" /db_xref="SubtiList:BG12386" /db_xref="UniProtKB/Swiss-Prot:O05263" /translation="MKRKASIMFVHQDKYEEYKQRHDDIWPEMAEALKAHGAHHYSIF LDEETGRLFAYLEIEDEEKWRKMADTEVCQRWWKSMAPLMKTNSDFSPVAIDLKEVFY LD*" gene complement(3064831..3065145) /gene="rhaM" /locus_tag="BSU_31190" /old_locus_tag="BSU31190" CDS complement(3065163..3066620) /gene="rhaB" /locus_tag="BSU_31200" /old_locus_tag="BSU31200" /EC_number="2.7.1.5" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:16674975, 26712933" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16674975, 26712933; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="rhamnulokinase" /protein_id="NP_390998.1" /db_xref="EnsemblGenomes-Gn:BSU31200" /db_xref="EnsemblGenomes-Tr:CAB15098" /db_xref="GOA:O05262" /db_xref="InterPro:IPR000577" /db_xref="InterPro:IPR013449" /db_xref="InterPro:IPR018484" /db_xref="InterPro:IPR018485" /db_xref="SubtiList:BG12385" /db_xref="UniProtKB/Swiss-Prot:O05262" /translation="MIYTAIDVGASSGRIMVGELNEGKLDIQEIHRFANGFSQRDGHC LWDIDHLLKQILQGLQKVKTLGYEHCTVGIDTWAVDYVLLDEKGDRLREAISYRDRRT DHTIDKLEHTLSKAAIYQKTGIQFQPFNTIYQLFEEDRELLKKTDKIMMIPDYLGYCL TGKAVTEITNVSTTQLLNVSTGNLDPELLEAVSVLEQQFAPLTEPGCELGKLRNEWFP DYDLPACKVMTVATHDTASAVIAAPGVNDGWAYISSGTWSLIGVENKTPIITDLALEN NYTNERGANNTIRFLKNIIGMWVIQEVKQQLQADYSFQQLAEEAKKTEPFQQFINLND KRFLNPENMIKEIQHYCRQTRQKIPRTAGELACCIYSNLAIIYAIAIKELETITEKPI EQFHIIGGGARNDFLNQLTADMSGKAVYAGPIEATATGNLLMQMIAAKEVKDIKEARQ VVRNSFPIKVFTPKDIDRSTIIQSFQQTVLKALSK*" gene complement(3065163..3066620) /gene="rhaB" /locus_tag="BSU_31200" /old_locus_tag="BSU31200" CDS complement(3066625..3067401) /gene="rhaR" /locus_tag="BSU_31210" /old_locus_tag="BSU31210" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:11496004, 26712933" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11496004, 26712933; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator of the rhamnose operon(RhaR / l-rhamnulose-1-phosphate)" /protein_id="NP_390999.1" /db_xref="EnsemblGenomes-Gn:BSU31210" /db_xref="EnsemblGenomes-Tr:CAB15099" /db_xref="GOA:O05261" /db_xref="InterPro:IPR001034" /db_xref="InterPro:IPR014036" /db_xref="InterPro:IPR018356" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG12384" /db_xref="UniProtKB/Swiss-Prot:O05261" /translation="MLVAERQQKIVEIVNMRSSIRVSELSDIFSVTEETIRRDLEKLE KEHKLSRSHGGAVSIQQKESEIHFSEREITNVIEKKAIAHEAAKYVKSGDRIILDAST TAWYMAKILPDIELTVITNSMKAAIELSNKENISVISTGGILLEKSLSFAGPLAERSL ETYHVNKTFLSCKGFDVHNGMSDSNEWQALLKKRMIERSDQTILMADSSKWGNREFSH IASLQDVSRLITDSGLDPASVKALEDKKVKVTAVPLSKRG*" gene complement(3066625..3067401) /gene="rhaR" /locus_tag="BSU_31210" /old_locus_tag="BSU31210" misc_feature complement(3067435..3067454) /Source="Nicolas_upshift_promotors" /id="U2421" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.99000999000999" /psig="0.999000999001" /xcortree=3189 /SigmaFactorBS="acgggctgcatgatcacggtagacggcggcgtccctgctgct tttacgcgttagataTATGCTATGATAAAAATATAagacggactacgatatgaggaag g" /listShort="yulB, yulC, yulD, yulE" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(3067451) /Source="Nicolas_upshifts" /id="U2421" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.99000999000999" /psig="0.999000999001" /xcortree=3189 /SigmaFactorBS="acgggctgcatgatcacggtagacggcggcgtccctgctgct tttacgcgttagataTATGCTATGATAAAAATATAagacggactacgatatgaggaag g" /listShort="yulB, yulC, yulD, yulE" /GFF_Attribute="listLong" CDS complement(3067458..3069527) /gene="rhaE" /locus_tag="BSU_31220" /old_locus_tag="BSU31220" /EC_number="1.1.1.-" /EC_number="4.1.2.19" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:24391637, 26712933" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 24391637, 26712933; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="bifunctional rhamnulose-1-phosphate aldolase/alcohol dehydrogenase" /protein_id="NP_391000.1" /db_xref="EnsemblGenomes-Gn:BSU31220" /db_xref="EnsemblGenomes-Tr:CAB15100" /db_xref="GOA:P40747" /db_xref="InterPro:IPR001303" /db_xref="InterPro:IPR002347" /db_xref="InterPro:IPR013454" /db_xref="InterPro:IPR036291" /db_xref="InterPro:IPR036409" /db_xref="SubtiList:BG10947" /db_xref="UniProtKB/Swiss-Prot:P40747" /translation="MVKHIWDSERAAQLPKGVEELVYRSNLIGSDRTVCNWGGGNTSM KTTEKDFRGREIEVMWVKGSGSDLATMKAHNFSGLKLDDIRPLIKRDQMPDEEMVDYL SHCMIDSKHPRPSIETLLHAFLPYKHVDHTHPDAIISICCADNGKQIAEDIYGNRFVW VPYVRPGFTLSKMIAEGVANNPHAELVLMEKHGLVTWGETSETCYQKTISIIQEAEQY INDRINQHEVFGGKRYQPLPEDKRKQILAGIMPVIRGAVSEEKKMILSYDDHDDVLEF VNSVQAPALSQIGAACPDHLVHTKRVPLYIDWNPETQDVHKLADLIKSGVETFTSEYQ AYFTRNQQDGDQIFESAPRVILIPGIGMVNTGKSYAMSKVSGALYRRAIAVMKGATAL GQFVSLHENESYHVEYWPLELYKLTLAPPEAEFSRKVALITGGAGGIGSAACRRFAAE GGHVIVADLNIEGAQKIAGEINDAYGKGRAMAVKMDVTKEEDVQSAFERAALAYGGID IVVNNAGLATSSPFDETSLKEWNLNMNVLGTGYFLVAREAFKQMKHQNRGGSMVFVGS KNSVYAGKNASAYSSVKALETHLARCIAAEGGEFGIRVNSVLPDAVLQGSAIWGSSWR EERAAAYGIEPDQLEEHYRKRTALLVNIYPEDIAEAIAFFASSKAEKTTGCMITVDGG VPAAFTR*" gene complement(3067458..3069527) /gene="rhaE" /locus_tag="BSU_31220" /old_locus_tag="BSU31220" promotor_-10 complement(3069560..3069579) /Source="Nicolas_upshift_promotors" /id="U2422" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.472527472527473" /psig=1 /xcortree=1572 /SigmaFactorBS="tttttttgttaaaaagcaaaaataaacaaaaacGATTCAAaa acaaacagaaaTCATATATAATGAAAACGGAtacaaataaaagggtatggaggaatat c" /listShort="yuxG, yulB, yulC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3069572) /Source="Nicolas_upshifts" /id="U2422" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.472527472527473" /psig=1 /xcortree=1572 /SigmaFactorBS="tttttttgttaaaaagcaaaaataaacaaaaacGATTCAAaa acaaacagaaaTCATATATAATGAAAACGGAtacaaataaaagggtatggaggaatat c" /listShort="yuxG, yulB, yulC" /GFF_Attribute="listLong" promotor_-35 complement(3069593..3069599) /Source="Nicolas_upshift_promotors" /id="U2422" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.472527472527473" /psig=1 /xcortree=1572 /SigmaFactorBS="tttttttgttaaaaagcaaaaataaacaaaaacGATTCAAaa acaaacagaaaTCATATATAATGAAAACGGAtacaaataaaagggtatggaggaatat c" /listShort="yuxG, yulB, yulC" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3069665..3071653) /gene="tlpB" /locus_tag="BSU_31230" /old_locus_tag="BSU31230" /function="16.12: Sense" /experiment="publication(s) with functional evidences, PMID:8188684, 10825179, 14563871" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8188684, 10825179, 14563871; Product type rc: receptor" /codon_start=1 /transl_table=11 /product="methyl-accepting chemotaxis protein" /protein_id="NP_391001.1" /db_xref="EnsemblGenomes-Gn:BSU31230" /db_xref="EnsemblGenomes-Tr:CAB15101" /db_xref="GOA:P39217" /db_xref="InterPro:IPR003122" /db_xref="InterPro:IPR003660" /db_xref="InterPro:IPR004089" /db_xref="InterPro:IPR029151" /db_xref="InterPro:IPR033479" /db_xref="SubtiList:BG10862" /db_xref="UniProtKB/Swiss-Prot:P39217" /translation="MGKFIQWIKQPSISKPLIAAFLAVLILPVGVLAYFSYQSAWNAL DRELISSAKGNVEELNSTLQNKLEDKVKAIDYYSETVDKDILLGKNKTLLKEKFKQYT TLNDDVGAIYAASEDKKLYKYPDSGVPKGFDPTGRDWYKQAVAEKGQAVFSEPYTDEA TGDIVVTISKQLKDGSGVIALDLNLDEVLTASKRIKIGKEGFAFITTGNKKYIAHPTI KPGTTGSGDWTNQVYSKKEGSFEYTFEGKEKKMAFTTNKLTGWKIAGTYFVSELQDAS SPVLNTAVIILCVSIVIGGILILYIIRAITKPLRKLVSTSAKISSGDLTEVIDIHSKN EFGQLGESFNEMSASLRSVIGVIQTSVENVASSSEELTASAAQTSKATEHITLAIEQF SDGNEAQSEKLETSSNHLSQMNEGISKVAQASSTITKSSIQSSEAAGSGEKLVEHTVG QMKTIDQSVQKAEAVVKGLETKSQDITSILNVINGIADQTNLLALNAAIEAARAGEYG RGFSVVAEEVRKLAVQSADSAKEIEGLIQEIVREISTSLSMFQSVNHEVKEGLQITDQ TAESFKQIYEMTTQISGELQNLNATVEQLSAGSQEVSSAVEDISAVAKESSAGIQDIA ASAEEQLASMEEISSSAETLANMAEELQDITKKFKIES*" gene complement(3069665..3071653) /gene="tlpB" /locus_tag="BSU_31230" /old_locus_tag="BSU31230" downshifts complement(3069684) /Source="Nicolas_upshifts" /id="D1616" /incds=0 /nref=108 /ntot=174 /MaxReadThrough="3.32915" /MaxDrop="6.75141" /score="18.7221191" /energy="-8.3" /TU="NA" /idTUdmin="U2423" /TUdmin="-2" /isTUend="TRUE" promotor_-35 3071657..3071664 /Source="Nicolas_upshift_promotors" /id="U2424" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.426573426573427" /psig="0.735264735264735" /xcortree=662 /SigmaFactorBS="ttgtatgaattttcccattctCGTTGACTcctcctttaagat aaATCTAATATCGTCAAACTAGgataaaaggtttaataaaaaaactaaaaaaaacacc c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(3071674..3071692) /Source="Nicolas_upshift_promotors" /id="U2423" /multdbtbs="SigD" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2793 /SigmaFactorBS="ttgttgcgcttgggtgttttttttagtttttttaTTAAACCT tttatcctagtttGACGATATTAGATTTATCTtaaaggaggagtcaacgagaatggga a" /listShort="tlpB" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-10 3071680..3071699 /Source="Nicolas_upshift_promotors" /id="U2424" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.426573426573427" /psig="0.735264735264735" /xcortree=662 /SigmaFactorBS="ttgtatgaattttcccattctCGTTGACTcctcctttaagat aaATCTAATATCGTCAAACTAGgataaaaggtttaataaaaaaactaaaaaaaacacc c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3071687) /Source="Nicolas_upshifts" /id="U2423" /multdbtbs="SigD" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2793 /SigmaFactorBS="ttgttgcgcttgggtgttttttttagtttttttaTTAAACCT tttatcctagtttGACGATATTAGATTTATCTtaaaggaggagtcaacgagaatggga a" /listShort="tlpB" /GFF_Attribute="listLong" upshifts 3071696 /Source="Nicolas_upshifts" /id="U2424" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.426573426573427" /psig="0.735264735264735" /xcortree=662 /SigmaFactorBS="ttgtatgaattttcccattctCGTTGACTcctcctttaagat aaATCTAATATCGTCAAACTAGgataaaaggtttaataaaaaaactaaaaaaaacacc c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(3071706..3071713) /Source="Nicolas_upshift_promotors" /id="U2423" /multdbtbs="SigD" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2793 /SigmaFactorBS="ttgttgcgcttgggtgttttttttagtttttttaTTAAACCT tttatcctagtttGACGATATTAGATTTATCTtaaaggaggagtcaacgagaatggga a" /listShort="tlpB" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 3071762 /Source="Nicolas_upshifts" /id="D1617" /incds=0 /nref=4 /ntot=11 /MaxReadThrough="1.04089" /MaxDrop="4.2056" /score="13.4355481" /energy="-10.7" /TU="NA" /idTUdmin="U2424" /TUdmin=22 /isTUend="TRUE" CDS complement(3071767..3073752) /gene="mcpA" /locus_tag="BSU_31240" /old_locus_tag="BSU31240" /function="16.12: Sense" /experiment="publication(s) with functional evidences, PMID:8188684, 9721285, 12011078" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8188684, 9721285, 12011078; Product type rc: receptor" /codon_start=1 /transl_table=11 /product="methyl-accepting chemotaxis protein" /protein_id="NP_391002.2" /db_xref="EnsemblGenomes-Gn:BSU31240" /db_xref="EnsemblGenomes-Tr:CAB15102" /db_xref="GOA:P39214" /db_xref="InterPro:IPR003122" /db_xref="InterPro:IPR003660" /db_xref="InterPro:IPR004089" /db_xref="InterPro:IPR029151" /db_xref="InterPro:IPR033479" /db_xref="SubtiList:BG10861" /db_xref="UniProtKB/Swiss-Prot:P39214" /translation="MKKILQLIKQRSITRKLLVSFLSILIIPVVILAIFAYQSASSSL DRQMMGSALENVQQLNEIINTSIGEKENSADYFSEWLTKEKYNAKSNASIAEKFSQYI SINKDVESIYTSDTKGHFTRYPDLPMPSGYNPVERDWYKKAVANKGKVVITDPYKTAS TNTMVVTIAQQTKDGSGVIAINMTIENLLKTTKKVNIGTQGYAFIMTKDKKVVAHPNE QSGTELKGDWLDKMLSADKGDFQYTMDGDKKKMAFDTNKLTGWKIGGTMYLDEIHEAA QPVLHLALIVLAAAIIIGIIVMTLIIRSITTPLKQLVGSSKRISEGDLTETIDIRSKD ELGELGKSFNNMASSLRSLIHAIQDSVDNVAASSEELTASAAQTSKATEHITLAIEQF SNGNEKQNENIETAAEHIYQMNDGLTNMAQASEVITDSSVQSTEIASEGGKLVHQTVG QMNVIDKSVKEAEQVVRGLETKSKDITNILRVINGIADQTNLLALNAAIEAARAGEYG RGFSVVAEEVRKLAVQSADSAKEIEGLIIEIVKEINTSLGMFQSVNQEVQTGLDITDK TEMSFKRISEMTNQIAGELQNMSATVQQLSASSEEVSGASEHIASISKESSAHIQDIA ASAEEQLASMEEISSSAETLSSMAEELRDMTKRFKIE*" gene complement(3071767..3073752) /gene="mcpA" /locus_tag="BSU_31240" /old_locus_tag="BSU31240" downshifts complement(3071772) /Source="Nicolas_upshifts" /id="D1618" /incds=0 /nref=196 /ntot=232 /MaxReadThrough="3.11319" /MaxDrop="7.54297" /score="40.6270404" /energy="-13.6" /TU="U2425" /idTUdmin="U2425" /TUdmin="-22" /isTUend="TRUE" promotor_-10 complement(3073773..3073791) /Source="Nicolas_upshift_promotors" /id="U2425" /multdbtbs="SigD" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2798 /SigmaFactorBS="aattagttacttttgttaaatttcttcttttttgctGTATAT ATttacccatttccaGCCGATATGAAGGGTAGCAtaaaaaaggagaaatgaatgatga a" /listShort="mcpA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3073788) /Source="Nicolas_upshifts" /id="U2425" /multdbtbs="SigD" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2798 /SigmaFactorBS="aattagttacttttgttaaatttcttcttttttgctGTATAT ATttacccatttccaGCCGATATGAAGGGTAGCAtaaaaaaggagaaatgaatgatga a" /listShort="mcpA" /GFF_Attribute="listLong" S_feature complement(3073790..3073877) /Source="Nicolas_S_feature" /locus_tag="new_3208192_3208279_c" /HighExp="GM 150, T0.0H, T-1.40H, T-0.40H, MG 150, T-5.40H, T-3.40H, T-1.10H, T-2.40H, M/G" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigD" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1190" promotor_-35 complement(3073805..3073812) /Source="Nicolas_upshift_promotors" /id="U2425" /multdbtbs="SigD" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2798 /SigmaFactorBS="aattagttacttttgttaaatttcttcttttttgctGTATAT ATttacccatttccaGCCGATATGAAGGGTAGCAtaaaaaaggagaaatgaatgatga a" /listShort="mcpA" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3073878..3075866) /gene="tlpA" /locus_tag="BSU_31250" /old_locus_tag="BSU31250" /function="16.12: Sense" /experiment="publication(s) with functional evidences, PMID:8188684, 10825179, 14563871, 26522943" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8188684, 10825179, 14563871, 26522943; Product type rc: receptor" /codon_start=1 /transl_table=11 /product="methyl-accepting chemotaxis protein (membrane curvature dependent localisation)" /protein_id="NP_391003.1" /db_xref="EnsemblGenomes-Gn:BSU31250" /db_xref="EnsemblGenomes-Tr:CAB15103" /db_xref="GOA:P39216" /db_xref="InterPro:IPR003122" /db_xref="InterPro:IPR003660" /db_xref="InterPro:IPR004089" /db_xref="InterPro:IPR029151" /db_xref="InterPro:IPR033479" /db_xref="SubtiList:BG10860" /db_xref="UniProtKB/Swiss-Prot:P39216" /translation="MKKTLTTIRRSSIARRLIISFLLILIVPITALSVSAYQSAVASL DVQMTQSAKENVQILDHIIDDKISTTEKSLAYFSDWATAEKFQDKKKTELKQEFKQFI QMNDNVAAVFSSGKDGDFTRYPYADMPSDFNALERDWYKEAMANKGKTIVTEPYESIS SGKMVVTIARQTVDGSGVVAIDMKIDDLVTTAKGINIGKEGYAFILSQNKKVIAYSGE KAGTELKGDWVDKLYKDKSGDFEYTYKGKKKKMAFATSQTTGWKISGTMYANEIHDAA SRVLIMASIVLAIAIGAGMTAIYFVIRSITKPLRRIVASAEKISEGDLTETIEINSKD ELGVLSESFNHMAHSLRSLIHGIKDSVEHVASSSEELTASADQTSRATEHITMAIEQF SNGSESQSEKIETTTEQINEMNDGLAELARAAAVITETSADSTEVSSKGETLVQKTAG QMNTIDHSVKAAEQVVKGLEIKSKDITNILRVINGIADQTNLLALNAAIEAARAGEYG RGFSVVAEEVRKLAVQSADSAKEIESLISEIVKEIHTSLNVLQSVNKEVETGLVMTDE TKQSFKHISQMTNQIASELQNMNATVEELSAGAQEISAASNDITAISKESSDGIQDIA ASAEEQLASMEEISSSALTLERMSEELRDLTKQFKVDK*" gene complement(3073878..3075866) /gene="tlpA" /locus_tag="BSU_31250" /old_locus_tag="BSU31250" promotor_-10 complement(3075891..3075909) /Source="Nicolas_upshift_promotors" /id="U2426" /multdbtbs="SigD" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2835 /SigmaFactorBS="atttagaactatttttcattttttcctccattttcaATGTAA TTtaaaggaagatccGCCGATATAATTTGTAAATtattgaaagaaggttcaaaaggaa a" /listShort="tlpA, S1190" /listLong="mcpA" /label="promotor_-10" upshifts complement(3075906) /Source="Nicolas_upshifts" /id="U2426" /multdbtbs="SigD" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2835 /SigmaFactorBS="atttagaactatttttcattttttcctccattttcaATGTAA TTtaaaggaagatccGCCGATATAATTTGTAAATtattgaaagaaggttcaaaaggaa a" /listShort="tlpA, S1190" /listLong="mcpA" promotor_-35 complement(3075923..3075930) /Source="Nicolas_upshift_promotors" /id="U2426" /multdbtbs="SigD" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2835 /SigmaFactorBS="atttagaactatttttcattttttcctccattttcaATGTAA TTtaaaggaagatccGCCGATATAATTTGTAAATtattgaaagaaggttcaaaaggaa a" /listShort="tlpA, S1190" /listLong="mcpA" /label="promotor_-35" CDS complement(3076043..3078031) /gene="mcpB" /locus_tag="BSU_31260" /old_locus_tag="BSU31260" /function="16.12: Sense" /experiment="publication(s) with functional evidences, PMID:12011078, 14731274, 15317802, 15544802, 19901023, 20864474, 22931217, 27899502" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12011078, 14731274, 15317802, 15544802, 19901023, 20864474, 22931217, 27899502; Product type rc: receptor" /codon_start=1 /transl_table=11 /product="methyl-accepting chemotaxis protein" /protein_id="NP_391004.2" /db_xref="EnsemblGenomes-Gn:BSU31260" /db_xref="EnsemblGenomes-Tr:CAB15104" /db_xref="GOA:P39215" /db_xref="InterPro:IPR003122" /db_xref="InterPro:IPR003660" /db_xref="InterPro:IPR004089" /db_xref="InterPro:IPR029151" /db_xref="InterPro:IPR033479" /db_xref="SubtiList:BG10859" /db_xref="UniProtKB/Swiss-Prot:P39215" /translation="MKTFINWLKKPSISKKLIVSFIAILIIPILILEFSSYRSASGKL DQEIMGNAKNSVDTFNTTVTNDLGEKAKAVTFFSESLKRSAFKGKSNQEEIKAKFSQY VSINQGVARIYGGADNGTYVQAPKEKLPEGYDPRQRPWYQDAMKAGGEIVVTDPYVAA SDGSMVITIAQELKDGSGVVAMDITIDKLLEQMKQIKVGKEGYAFIATKNKTYVAHKN HKAGEKLSGDWVAKMYANDSGELQYTLNNEDKKMTYTTNELTGWKIAGTMYMDEIKDA SKSVLTTGMIVLIASIVAGGILILFIVRSITKPLKRLVQSSKTISRGDLTETIEIHSK DELGELGESFNEMGQSLRSLISAIQDSVNNVAASSEQLTASAGQTSKATEHITMAIEQ FSNGNEEQSEKVESSSHQLNLMNEGLQQVSQTSSDITKASIQSTEIAGTGEKFVQQTV GQMNSINQSVQQAEAVVKGLEGKSKDITSILRVINGIADQTNLLALNAAIEAARAGES GRGFSVVAEEVRKLAVQSADSAKEIEKLIQEIVAEIDTSLHMFKEVNQEVQSGLVVTD NTKESFQSIFSMTNEIAGKLQTMNSTVEQLSDRSQHVSAAVSGIADVSKESSASIQDI AASAEEQLASMEEISSSATTLAQMAEELRDLTKQFKIE*" gene complement(3076043..3078031) /gene="mcpB" /locus_tag="BSU_31260" /old_locus_tag="BSU31260" downshifts complement(3076062) /Source="Nicolas_upshifts" /id="D1619" /incds=0 /nref=136 /ntot=224 /MaxReadThrough="3.76161" /MaxDrop="7.09773" /score="30.8363643" /energy="-10.7" /TU="U2427" /idTUdmin="U2427" /TUdmin="-132" /isTUend="FALSE" promotor_-10 complement(3078052..3078070) /Source="Nicolas_upshift_promotors" /id="U2427" /multdbtbs="SigD" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2799 /SigmaFactorBS="aaaaaggcagaagacagccaaaaagaacttcttccatttttt aTTTTAAAActtttttaagcaGCCGATATATACTGTATCAaacctgaaggagcaagtg a" /listShort="mcpB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3078073) /Source="Nicolas_upshifts" /id="U2427" /multdbtbs="SigD" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2799 /SigmaFactorBS="aaaaaggcagaagacagccaaaaagaacttcttccatttttt aTTTTAAAActtttttaagcaGCCGATATATACTGTATCAaacctgaaggagcaagtg a" /listShort="mcpB" /GFF_Attribute="listLong" promotor_-35 complement(3078083..3078090) /Source="Nicolas_upshift_promotors" /id="U2427" /multdbtbs="SigD" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2799 /SigmaFactorBS="aaaaaggcagaagacagccaaaaagaacttcttccatttttt aTTTTAAAActtttttaagcaGCCGATATATACTGTATCAaacctgaaggagcaagtg a" /listShort="mcpB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 3078133..3078142 /Source="Nicolas_upshift_promotors" /id="U2428" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1304 /SigmaFactorBS="ggaagaagttctttttggctgtcttctgccttttTAACTTTC ATtgcccaagctcttTGCATATCTTATAAAAAACAaggggggctaaacatgattattg t" /listShort="tgl, S1191" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3078156..3078175 /Source="Nicolas_upshift_promotors" /id="U2428" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1304 /SigmaFactorBS="ggaagaagttctttttggctgtcttctgccttttTAACTTTC ATtgcccaagctcttTGCATATCTTATAAAAAACAaggggggctaaacatgattattg t" /listShort="tgl, S1191" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3078159 /Source="Nicolas_upshifts" /id="U2428" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1304 /SigmaFactorBS="ggaagaagttctttttggctgtcttctgccttttTAACTTTC ATtgcccaagctcttTGCATATCTTATAAAAAACAaggggggctaaacatgattattg t" /listShort="tgl, S1191" /GFF_Attribute="listLong" CDS 3078189..3078926 /gene="tgl" /locus_tag="BSU_31270" /old_locus_tag="BSU31270" /EC_number="2.3.2.13" /function="16.13: Shape" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:9692191, 16267299, 16751597, 16936016, 18249137, 26322858" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9692191, 16267299, 16751597, 16936016, 18249137, 26322858; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="protein-glutamine gamma-glutamyltransferase (transglutaminase)" /protein_id="NP_391005.1" /db_xref="EnsemblGenomes-Gn:BSU31270" /db_xref="EnsemblGenomes-Tr:CAB15105" /db_xref="GOA:P40746" /db_xref="InterPro:IPR020916" /db_xref="PDB:4P8I" /db_xref="PDB:4PA5" /db_xref="SubtiList:BG10946" /db_xref="UniProtKB/Swiss-Prot:P40746" /translation="MIIVSGQLLRPQDIENWQIDQDLNPLLKEMIETPVQFDYHSIAE LMFELKLRMNIVAAAKTLHKSGAKFATFLKTYGNTTYWRVSPEGALELKYRMPPSKAI RDIAENGPFYAFECATAIVIIYYLALIDTIGEDKFNASFDRIILYDWHYEKLPIYTET GHHFFLGDCLYFKNPEFDPQKAQWRGENVILLGEDKYFAHGLGILNGKQIIDKLNSFR KKGALQSAYLLSQATRLDVPSLFRIVR*" gene 3078189..3078926 /gene="tgl" /locus_tag="BSU_31270" /old_locus_tag="BSU31270" promotor_-10 complement(3078214..3078233) /Source="Nicolas_upshift_promotors" /id="U2429" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.694305694305694" /psig=1 /xcortree=1815 /SigmaFactorBS="caatcatctcttttaagagcggattcagaTCTTGatcaatct gccaattTTCAATATCCTGGGGACGGAgcaattgtcctgatacaataatcatgtttag c" /GFF_Attribute="listShort" /listLong="mcpB" /label="promotor_-10" upshifts complement(3078222) /Source="Nicolas_upshifts" /id="U2429" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.694305694305694" /psig=1 /xcortree=1815 /SigmaFactorBS="caatcatctcttttaagagcggattcagaTCTTGatcaatct gccaattTTCAATATCCTGGGGACGGAgcaattgtcctgatacaataatcatgtttag c" /GFF_Attribute="listShort" /listLong="mcpB" promotor_-35 complement(3078249..3078253) /Source="Nicolas_upshift_promotors" /id="U2429" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.694305694305694" /psig=1 /xcortree=1815 /SigmaFactorBS="caatcatctcttttaagagcggattcagaTCTTGatcaatct gccaattTTCAATATCCTGGGGACGGAgcaattgtcctgatacaataatcatgtttag c" /GFF_Attribute="listShort" /listLong="mcpB" /label="promotor_-35" S_feature 3078927..3081747 /Source="Nicolas_S_feature" /locus_tag="new_3213329_3216149" /HighExp="S6, S8, S7, BT, S5, C30, B36, Pyr, BC, C90" /AntisenseName="yugT" /AntisenseCor="0.63350809138227804" /AntisenseRegPval="-30.9" /CDS_PredictionProba="0.61985900000000005" /TUshortSig="SigK" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1191" CDS complement(3078940..3079194) /gene="yuzH" /locus_tag="BSU_31279" /old_locus_tag="BSU31279" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="YP_003097776.1" /db_xref="EnsemblGenomes-Gn:BSU31279" /db_xref="EnsemblGenomes-Tr:CAX52682" /db_xref="UniProtKB/Swiss-Prot:C0H3Q3" /translation="MNILQYSYKKRGKIEFVFEGWPHSKVTMVPIKGYYFVRFIKWSS QDPIVTRNDLEKMEWAANQYFGTAPFYRKRKAFETPSSGK*" gene complement(3078940..3079194) /gene="yuzH" /locus_tag="BSU_31279" /old_locus_tag="BSU31279" downshifts complement(3078966) /Source="Nicolas_upshifts" /id="D1620" /incds=0 /nref=1 /ntot=13 /MaxReadThrough="2.39206" /MaxDrop="2.92958" /score="-2.51333596" /energy="-14.7" /TU="NA" /idTUdmin="U2430" /TUdmin=0 /isTUend="TRUE" S_feature complement(3079195..3079451) /Source="Nicolas_S_feature" /locus_tag="new_3213597_3213853_c" /HighExp="Etha, Sw, Salt, Gly, BC, M9-stat, Lbstat, Heat, LPhT, S0" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.37980700000000001" /TUshortSig="SigB" /TUshortPSig="0.969" /TUlongSig="NA" /TUlongPSig="NA" /label="S1192" CDS complement(3079452..3079850) /gene="yugU" /locus_tag="BSU_31280" /old_locus_tag="BSU31280" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_391006.2" /db_xref="EnsemblGenomes-Gn:BSU31280" /db_xref="EnsemblGenomes-Tr:CAB15106" /db_xref="InterPro:IPR001602" /db_xref="InterPro:IPR035917" /db_xref="SubtiList:BG12373" /db_xref="UniProtKB/Swiss-Prot:O05243" /translation="MLKTLQIKTTKRDEMIDITREVEAFLQETGITSGAALIYCPHTT AGITINENADPDVKKDMLRRFDEVYPWEHELDRHMEGNTAAHMKSSTVGASQHVIVEN GRLILGTWQGIYFCEFDGPRTRTCYIKMMG*" gene complement(3079452..3079850) /gene="yugU" /locus_tag="BSU_31280" /old_locus_tag="BSU31280" CDS complement(3079810..3079944) /locus_tag="BSU_31289" /old_locus_tag="BSU31289" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_009514000.1" /translation="MFYRVYESGLTGKKRTQNELSDESGQTKGETNAENTANQNNQTR *" gene complement(3079810..3079944) /locus_tag="BSU_31289" /old_locus_tag="BSU31289" promotor_-10 complement(3079893..3079912) /Source="Nicolas_upshift_promotors" /id="U2430" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.96903096903097" /psig="0.96903096903097" /xcortree=145 /SigmaFactorBS="ttagactggagtttttttgttttatcgGGTTTATgagagcgg tttaacAGGAAAAAAAAGAACACAGAacgaattaagcgatgagagcggacaaacgaaa g" /listShort="yugU, S1192, yuzH" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3079900) /Source="Nicolas_upshifts" /id="U2430" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.96903096903097" /psig="0.96903096903097" /xcortree=145 /SigmaFactorBS="ttagactggagtttttttgttttatcgGGTTTATgagagcgg tttaacAGGAAAAAAAAGAACACAGAacgaattaagcgatgagagcggacaaacgaaa g" /listShort="yugU, S1192, yuzH" /GFF_Attribute="listLong" promotor_-35 complement(3079927..3079933) /Source="Nicolas_upshift_promotors" /id="U2430" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.96903096903097" /psig="0.96903096903097" /xcortree=145 /SigmaFactorBS="ttagactggagtttttttgttttatcgGGTTTATgagagcgg tttaacAGGAAAAAAAAGAACACAGAacgaattaagcgatgagagcggacaaacgaaa g" /listShort="yugU, S1192, yuzH" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3079970..3081634) /gene="yugT" /locus_tag="BSU_31290" /old_locus_tag="BSU31290" /EC_number="3.2.1.10" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 1761534; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative oligo-1,6-glucosidase" /protein_id="NP_391007.2" /db_xref="EnsemblGenomes-Gn:BSU31290" /db_xref="EnsemblGenomes-Tr:CAB15118" /db_xref="GOA:O05242" /db_xref="InterPro:IPR006047" /db_xref="InterPro:IPR017853" /db_xref="InterPro:IPR032091" /db_xref="SubtiList:BG12372" /db_xref="UniProtKB/Swiss-Prot:O05242" /translation="MKKAWWKEAVVYQIYPRSFKDSNGDGIGDIQGIRTKLSYIKELG ADVIWICPLYDSPNADNGYDIRDYQNILSEFGTMEDFDELLGDIHDLDMKLIMDLVVN HTSDEHPWFIESRSSIHSEKRDWYIWKDGKNGKTPNNWESIFGGPAWEYDQKTSQYYL HLFDKKQPDLNWENEKVRNAVYDMINWWLDKGIDGFRVDAITHIKKKEGFPDMPNPKG LDYVPSFPYHMNADGIMDLLTELKENTFSRYPIMTVGEANGVAAKEAADWAGEKNGIF SMIFQFEHLGLWDVEINESIDIVAFKRILTDWQDSLEGIGWNALFMENHDQPRSVSVW GDDGVYLKESAKALSAVYFLMKGTPFIYQGQELGMTNVAFPSIEDYDDVALKRLYETK TAKGTSHEDVMKIVWKKGRDNSRTPMQWNAGPYAGFSEAKPWIGINENYKWLNAEAQK NDKTSVYHFYKSLIKLRQTYDVFINGTYELILPEDQQIFAYLRKNESHTALIAANLTG TPALFRHSGLPLSSDALVLSNIETEPHKHMTSVLLKPYEARIYLWC*" gene complement(3079970..3081634) /gene="yugT" /locus_tag="BSU_31290" /old_locus_tag="BSU31290" downshifts complement(3079986) /Source="Nicolas_upshifts" /id="D1621" /incds=0 /nref=13 /ntot=38 /MaxReadThrough="1.79723" /MaxDrop="4.64379" /score="19.4176812" /energy="-6.5" /TU="NA" /idTUdmin="U2432" /TUdmin="-7" /isTUend="TRUE" promotor_-10 complement(3080942..3080961) /Source="Nicolas_upshift_promotors" /id="U2431" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.944055944055944" /psig="0.993006993006993" /xcortree=2467 /SigmaFactorBS="tttcctgacatgccgaatccaaaggGACTGGACtatgtccct tcctTTCCTTATCATATGAATGCTgacggcattatggatttgttaacagagctgaagg a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3080947) /Source="Nicolas_upshifts" /id="U2431" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.944055944055944" /psig="0.993006993006993" /xcortree=2467 /SigmaFactorBS="tttcctgacatgccgaatccaaaggGACTGGACtatgtccct tcctTTCCTTATCATATGAATGCTgacggcattatggatttgttaacagagctgaagg a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(3080975..3080982) /Source="Nicolas_upshift_promotors" /id="U2431" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.944055944055944" /psig="0.993006993006993" /xcortree=2467 /SigmaFactorBS="tttcctgacatgccgaatccaaaggGACTGGACtatgtccct tcctTTCCTTATCATATGAATGCTgacggcattatggatttgttaacagagctgaagg a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(3081659..3081677) /Source="Nicolas_upshift_promotors" /id="U2432" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.987012987012987" /psig="0.987012987012987" /xcortree=1123 /SigmaFactorBS="gctgttttttgtgtcatcaagtcatttcttaaaaagcaATGC TGtaaagacctttttctACATAGGATATATAAGAACggtacactgggaaggagtggct g" /listShort="yugT" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3081676) /Source="Nicolas_upshifts" /id="U2432" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.987012987012987" /psig="0.987012987012987" /xcortree=1123 /SigmaFactorBS="gctgttttttgtgtcatcaagtcatttcttaaaaagcaATGC TGtaaagacctttttctACATAGGATATATAAGAACggtacactgggaaggagtggct g" /listShort="yugT" /GFF_Attribute="listLong" promotor_-35 complement(3081693..3081698) /Source="Nicolas_upshift_promotors" /id="U2432" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.987012987012987" /psig="0.987012987012987" /xcortree=1123 /SigmaFactorBS="gctgttttttgtgtcatcaagtcatttcttaaaaagcaATGC TGtaaagacctttttctACATAGGATATATAAGAACggtacactgggaaggagtggct g" /listShort="yugT" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3081761..3083050) /gene="yugS" /locus_tag="BSU_31300" /old_locus_tag="BSU31300" /function="16.1: Circulate" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative membrane protein" /protein_id="NP_391008.2" /db_xref="EnsemblGenomes-Gn:BSU31300" /db_xref="EnsemblGenomes-Tr:CAB15119" /db_xref="GOA:O05241" /db_xref="InterPro:IPR000644" /db_xref="InterPro:IPR002550" /db_xref="InterPro:IPR005170" /db_xref="InterPro:IPR016169" /db_xref="InterPro:IPR036318" /db_xref="SubtiList:BG12371" /db_xref="UniProtKB/Swiss-Prot:O05241" /translation="MLILQLIAIFVLIGITAVFVAAEFAIVKIRGSKINQLIESGDSR ALAAHKIISNLDEYLSACQLGITITALGLGWLGEPTFERFLHPLFTMTGIPEPFNHIV TFVVAFIIVTFLHVVMGELAPKTVSIQKAEAVSLWIAKPLIWFYKITYPFIKALNGSA SFLVKLFGFHSVKEHQVVISEEELRLILSESYEKGEINQSEFRYVNKIFEFDNRVARE IMIPRTEIAVISLEQSLEEAIHHIINERYTRYPVIKDDKDHILGIINSKDMFKAYFLG QPIKLNQIMRPVIRVIESIPVQQLLIRMQKERIHMAILVDEYGGTAGLVTVEDIIEEI VGEIRDEYDQDETPHILKKGEHHYVMDGKALIDEVNDLLDIAIENEEIDTIAGWLLTQ KMELKAGDVIHAEGCEFKILDAEDHHIRFVEIKKTDF*" gene complement(3081761..3083050) /gene="yugS" /locus_tag="BSU_31300" /old_locus_tag="BSU31300" downshifts complement(3081770) /Source="Nicolas_upshifts" /id="D1622" /incds=0 /nref=5 /ntot=28 /MaxReadThrough="0.89237" /MaxDrop="3.67001" /score="3.60520478" /energy="-7.6" /TU="NA" /idTUdmin="U2434" /TUdmin=13 /isTUend="TRUE" promotor_-35 3082579..3082585 /Source="Nicolas_upshift_promotors" /id="U2433" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=254 /SigmaFactorBS="aagccaaacaatttcacaagaaaacttgcagagcCGTTTAAt gctttaataaacGGGTACGTGATTTTATAAAaccagatcagcggctttgcaatccata a" /listShort="S1193" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3082599..3082617 /Source="Nicolas_upshift_promotors" /id="U2433" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=254 /SigmaFactorBS="aagccaaacaatttcacaagaaaacttgcagagcCGTTTAAt gctttaataaacGGGTACGTGATTTTATAAAaccagatcagcggctttgcaatccata a" /listShort="S1193" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3082605 /Source="Nicolas_upshifts" /id="U2433" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=254 /SigmaFactorBS="aagccaaacaatttcacaagaaaacttgcagagcCGTTTAAt gctttaataaacGGGTACGTGATTTTATAAAaccagatcagcggctttgcaatccata a" /listShort="S1193" /GFF_Attribute="listLong" S_feature 3082609..3083261 /Source="Nicolas_S_feature" /locus_tag="new_3217011_3217663" /HighExp="Etha, Sw, Gly, Salt, BC, B60, Heat, S8, B36, HiTm" /AntisenseName="yugS" /AntisenseCor="0.12310225183111501" /AntisenseRegPval="-1.4" /CDS_PredictionProba="NA" /TUshortSig="SigB" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1193" CDS complement(3083094..3083771) /gene="yugP" /locus_tag="BSU_31310" /old_locus_tag="BSU31310" /function="16.6: Maintain" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16704729, 16850406, 24383880; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative metal-dependent protease/peptidase" /protein_id="NP_391009.1" /db_xref="EnsemblGenomes-Gn:BSU31310" /db_xref="EnsemblGenomes-Tr:CAB15120" /db_xref="GOA:O05248" /db_xref="InterPro:IPR007395" /db_xref="SubtiList:BG12370" /db_xref="UniProtKB/Swiss-Prot:O05248" /translation="MLFIFLTIAALGLSFWAQFKVKSNFEKYSKVEASSGRTGAETAR RILDINGLYDVPVEPVRGTLTDHYDPTRRVVRLSEPVYYGRSISAISVASHEVGHALQ HQESYGALVLRHKIFPVVNFASGVAPLLFLGGMLLGSLNLIGLGIILFSAAVFFQLIT LPVEFNASSRAKQIIVSEGFIRNNEENGVNKVLSAAALTYVAAALVSLFELLRFVMIF LNGRDEN*" gene complement(3083094..3083771) /gene="yugP" /locus_tag="BSU_31310" /old_locus_tag="BSU31310" downshifts complement(3083104) /Source="Nicolas_upshifts" /id="D1623" /incds=0 /nref=153 /ntot=249 /MaxReadThrough="3.51629" /MaxDrop="4.854" /score="33.0420688" /energy="-13" /TU="U2434,U2435" /idTUdmin="U2435" /TUdmin="-243" /isTUend="FALSE" S_feature 3083446..3084122 /Source="Nicolas_S_feature" /locus_tag="new_3217848_3218524" /HighExp="Sw, S8, Salt, BC, S7, Etha, Gly, B36, B60, LPhT" /AntisenseName="yuzI" /AntisenseCor="0.20035821815170399" /AntisenseRegPval="-3" /CDS_PredictionProba="NA" /TUshortSig="NA" /TUshortPSig="NA" /TUlongSig="NA" /TUlongPSig="NA" /label="S1194" promotor_-10 complement(3083806..3083825) /Source="Nicolas_upshift_promotors" /id="U2434" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.74925074925075" /psig="0.999000999001" /xcortree=2033 /SigmaFactorBS="ctgattggattgtgtgctccaagccggaagaaaaagcgcatT TCTGTACacgagaaagaaaaCTCATTAAAATAATCGTAATagagaaatgatcatgaac a" /listShort="yugP, yugS" /GFF_Attribute="listLong" /label="promotor_-10" CDS complement(3083813..3084076) /gene="yuzI" /locus_tag="BSU_31319" /old_locus_tag="BSU31319" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 16704729; Product type f : factor" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="YP_003097777.1" /db_xref="EnsemblGenomes-Gn:BSU31319" /db_xref="EnsemblGenomes-Tr:CAX52683" /db_xref="GOA:C0H3Q4" /db_xref="UniProtKB/Swiss-Prot:C0H3Q4" /translation="MTIFQRTIVVLIGTQLAASAVILFIFDLNSYNHFSGSFSWLHFL KELAGSFAFYLFSAGLFFLLIGLCAPSRKKKRISVHEKENSLK*" gene complement(3083813..3084076) /gene="yuzI" /locus_tag="BSU_31319" /old_locus_tag="BSU31319" upshifts complement(3083827) /Source="Nicolas_upshifts" /id="U2434" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.74925074925075" /psig="0.999000999001" /xcortree=2033 /SigmaFactorBS="ctgattggattgtgtgctccaagccggaagaaaaagcgcatT TCTGTACacgagaaagaaaaCTCATTAAAATAATCGTAATagagaaatgatcatgaac a" /listShort="yugP, yugS" /GFF_Attribute="listLong" promotor_-35 complement(3083839..3083846) /Source="Nicolas_upshift_promotors" /id="U2434" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.74925074925075" /psig="0.999000999001" /xcortree=2033 /SigmaFactorBS="ctgattggattgtgtgctccaagccggaagaaaaagcgcatT TCTGTACacgagaaagaaaaCTCATTAAAATAATCGTAATagagaaatgatcatgaac a" /listShort="yugP, yugS" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(3084088..3084106) /Source="Nicolas_upshift_promotors" /id="U2435" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1079 /SigmaFactorBS="cccacttccggtgatgtttttcaaaaaatgtacaaAACATAt aaaaccggatttctCCATAAACTAAAACAAAAAggatgaaaaagatgacgatctttca a" /listShort="yuzI, yugP, yugS" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3084102) /Source="Nicolas_upshifts" /id="U2435" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1079 /SigmaFactorBS="cccacttccggtgatgtttttcaaaaaatgtacaaAACATAt aaaaccggatttctCCATAAACTAAAACAAAAAggatgaaaaagatgacgatctttca a" /listShort="yuzI, yugP, yugS" /GFF_Attribute="listLong" promotor_-35 complement(3084122..3084127) /Source="Nicolas_upshift_promotors" /id="U2435" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1079 /SigmaFactorBS="cccacttccggtgatgtttttcaaaaaatgtacaaAACATAt aaaaccggatttctCCATAAACTAAAACAAAAAggatgaaaaagatgacgatctttca a" /listShort="yuzI, yugP, yugS" /GFF_Attribute="listLong" /label="promotor_-35" CDS 3084123..3084455 /gene="mstX" /locus_tag="BSU_31321" /old_locus_tag="BSU31321" /function="16.5: Explore" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:15731457, 23737939, 25297828" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15731457, 23737939, 25297828; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="atypical membrane-integrating regulator of biofilm formation (Mistic protein)" /protein_id="YP_003097778.1" /db_xref="EnsemblGenomes-Gn:BSU31321" /db_xref="EnsemblGenomes-Tr:CAX52684" /db_xref="GOA:Q5BU39" /db_xref="InterPro:IPR021078" /db_xref="PDB:1YGM" /db_xref="UniProtKB/Swiss-Prot:Q5BU39" /translation="MFCTFFEKHHRKWDILLEKSTGVMEAMKVTSEEKEQLSTAIDRM NEGLDAFIQLYNESEIDEPLIQLDDDTAELMKQARDMYGQEKLNEKLNTIIKQILSIS VSEEGEKE*" gene 3084123..3084455 /gene="mstX" /locus_tag="BSU_31321" /old_locus_tag="BSU31321" promotor_-35 3084140..3084146 /Source="Nicolas_upshift_promotors" /id="U2436" /multdbtbs="-" /comp="M3" /sig="Sig-" /pcomp="0.497502497502497" /psig="0.497502497502497" /xcortree=1012 /SigmaFactorBS="tccggttttatatgttttgtacatttttTGAAAAAcatcacc ggaagtgGGACATACTGTTAGAAAAaagcacgggtgtgatggaagctatgaaagtgac g" /listShort="mstX, yugO" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3084161..3084178 /Source="Nicolas_upshift_promotors" /id="U2436" /multdbtbs="-" /comp="M3" /sig="Sig-" /pcomp="0.497502497502497" /psig="0.497502497502497" /xcortree=1012 /SigmaFactorBS="tccggttttatatgttttgtacatttttTGAAAAAcatcacc ggaagtgGGACATACTGTTAGAAAAaagcacgggtgtgatggaagctatgaaagtgac g" /listShort="mstX, yugO" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3084172 /Source="Nicolas_upshifts" /id="U2436" /multdbtbs="-" /comp="M3" /sig="Sig-" /pcomp="0.497502497502497" /psig="0.497502497502497" /xcortree=1012 /SigmaFactorBS="tccggttttatatgttttgtacatttttTGAAAAAcatcacc ggaagtgGGACATACTGTTAGAAAAaagcacgggtgtgatggaagctatgaaagtgac g" /listShort="mstX, yugO" /GFF_Attribute="listLong" CDS 3084452..3085438 /gene="kbfO" /locus_tag="BSU_31322" /old_locus_tag="BSU31322" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:16704729, 23737939, 25297828" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16704729, 23737939, 25297828; Product type t: transporter" /codon_start=1 /transl_table=11 /product="potassium channel protein involved in biofilm formation" /protein_id="NP_391010.3" /db_xref="EnsemblGenomes-Gn:BSU31322" /db_xref="EnsemblGenomes-Tr:CAB15121" /db_xref="GOA:Q795M8" /db_xref="InterPro:IPR003148" /db_xref="InterPro:IPR013099" /db_xref="InterPro:IPR028325" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG12369" /db_xref="UniProtKB/Swiss-Prot:Q795M8" /translation="MKSNRIFISWLRWPLFIRIGVIILCLILLFGQIIYILEPKQFTS VFEGIWWAVVTVSTVGYGDYVPHTPLGQAAGILLILSGASFVTAYFATLSAAAFSRQH RYIEGKVAYKGRDHIILIGWNEKTNRLLKDLQLAAPSKTVVLIDESLTEGPLIENVHF IRGHAADDGTLKRANITEAESVMITADQYKSETDADMLSVLTLLSVKGLNPLAYCIVE ILTDRFVTNAERAGANQIIGTSEFISRAMLQHYQVKLRPSKQQNGIKLTLDQHVELLA VPDELKGAAYKTCVLYFLDHNTTIIGIQKKEGPMLSPPLTYKVLETDQFLAI*" gene 3084452..3085438 /gene="kbfO" /locus_tag="BSU_31322" /old_locus_tag="BSU31322" downshifts complement(3085413) /Source="Nicolas_upshifts" /id="D1624" /incds=0 /nref=44 /ntot=128 /MaxReadThrough="0.617940000000001" /MaxDrop="4.76695" /score="21.5904825" /energy="-11.3" /TU="NA" /idTUdmin="U2437" /TUdmin=0 /isTUend="TRUE" CDS complement(3085435..3085839) /gene="yugN" /locus_tag="BSU_31330" /old_locus_tag="BSU31330" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_391011.1" /db_xref="EnsemblGenomes-Gn:BSU31330" /db_xref="EnsemblGenomes-Tr:CAB15122" /db_xref="InterPro:IPR014967" /db_xref="InterPro:IPR036491" /db_xref="SubtiList:BG12368" /db_xref="UniProtKB/Swiss-Prot:O05246" /translation="MIPIPSAIDGQSFLLQELEQVMKPLGYVINGGWEYDHGYFDYKI DDRDGYLFLRIPVNAVQGSLDERGAAVRIGTPFMLRQVFQADVDDHAEGGPFQSLFNQ FSEPERRDAEIDPAFLDIGASLVKELEDVLLH*" gene complement(3085435..3085839) /gene="yugN" /locus_tag="BSU_31330" /old_locus_tag="BSU31330" S_feature complement(3085840..3085898) /Source="Nicolas_S_feature" /locus_tag="new_3220242_3220300_c" /HighExp="M0t90, M40t90, S6, S8, S7, T0.30H, Lbstat, M9-stat, T1.30H, BC" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigEF, Sig-, SigA" /TUshortPSig="0.686, 0.141, 0.984" /TUlongSig="SigA" /TUlongPSig="0.988" /label="S1195" CDS complement(3085899..3086270) /gene="yugM" /locus_tag="BSU_31340" /old_locus_tag="BSU31340" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative transporter" /protein_id="NP_391012.1" /db_xref="EnsemblGenomes-Gn:BSU31340" /db_xref="EnsemblGenomes-Tr:CAB15123" /db_xref="GOA:O05245" /db_xref="SubtiList:BG12367" /db_xref="UniProtKB/Swiss-Prot:O05245" /translation="MFMKQLVKHLIIAGFSAAILSFLISFDAVYTGFSSSFGGTLSHF FIHSFLLIGLPLALFTDAVHRILHLKRTHTLFTKLGLYATVVYVSWDSAVWLAAAMAV YFLIECAFFPVGRAKETTISM*" gene complement(3085899..3086270) /gene="yugM" /locus_tag="BSU_31340" /old_locus_tag="BSU31340" CDS complement(3086329..3087681) /gene="pgi" /locus_tag="BSU_31350" /old_locus_tag="BSU31350" /EC_number="5.3.1.9" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 4214896, 4275311, 11489127, 19052382, 21453533, 22720735, 24705866; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="glucose-6-phosphate isomerase" /protein_id="NP_391013.2" /db_xref="EnsemblGenomes-Gn:BSU31350" /db_xref="EnsemblGenomes-Tr:CAB15124" /db_xref="GOA:P80860" /db_xref="InterPro:IPR001672" /db_xref="InterPro:IPR018189" /db_xref="InterPro:IPR035476" /db_xref="InterPro:IPR035482" /db_xref="SubtiList:BG12366" /db_xref="UniProtKB/Swiss-Prot:P80860" /translation="MTHVRFDYSKALTFFNEHELTYLRDFVKTAHHNIHEKTGAGSDF LGWVDLPEHYDKEEFARIKKSAEKIKSDSDVLLVVGIGGSYLGARAAIEALNHAFYNT LPKAKRGNPQVIFIGNNISSSYMRDVMDLLEDVDFSINVISKSGTTTEPAIAFRIFRK LLEEKYGKEEAKARIYATTDKERGALKTLSNEEGFESFVIPDDVGGRYSVLTAVGLLP IAVSGVNIDDMMKGALDASKDFATSELEDNPAYQYAVVRNVLYNKGKTIEMLINYEPA LQYFAEWWKQLFGESEGKDEKGIYPSSANYSTDLHSLGQYVQEGRRDLFETVLNVEKP KHELTIEEADNDLDGLNYLAGKTVDFVNKKAFQGTMLAHTDGNVPNLIVNIPELNAYT FGYLVYFFEKACAMSGYLLGVNPFDQPGVEAYKVNMFALLGKPGFEEKKAELEKRLED *" gene complement(3086329..3087681) /gene="pgi" /locus_tag="BSU_31350" /old_locus_tag="BSU31350" downshifts complement(3086340) /Source="Nicolas_upshifts" /id="D1625" /incds=0 /nref=90 /ntot=198 /MaxReadThrough="6.86736" /MaxDrop="4.4585" /score="24.139293" /energy="-16.8" /TU="U2437,U2438,U2439" /idTUdmin="U2441" /TUdmin=19 /isTUend="TRUE" promotor_-10 complement(3086496..3086514) /Source="Nicolas_upshift_promotors" /id="U2437" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.686313686313686" /psig="0.686313686313686" /xcortree=764 /SigmaFactorBS="tgcttgcccatacagacggaaatgttccgaacttaatcGTTA ACattcctgagctgaatGCATATACTTTTGGATACCttgtatatttcttcgaaaaagc c" /listShort="yugM, S1195, yugN" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3086513) /Source="Nicolas_upshifts" /id="U2437" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.686313686313686" /psig="0.686313686313686" /xcortree=764 /SigmaFactorBS="tgcttgcccatacagacggaaatgttccgaacttaatcGTTA ACattcctgagctgaatGCATATACTTTTGGATACCttgtatatttcttcgaaaaagc c" /listShort="yugM, S1195, yugN" /GFF_Attribute="listLong" promotor_-35 complement(3086530..3086535) /Source="Nicolas_upshift_promotors" /id="U2437" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.686313686313686" /psig="0.686313686313686" /xcortree=764 /SigmaFactorBS="tgcttgcccatacagacggaaatgttccgaacttaatcGTTA ACattcctgagctgaatGCATATACTTTTGGATACCttgtatatttcttcgaaaaagc c" /listShort="yugM, S1195, yugN" /GFF_Attribute="listLong" /label="promotor_-35" upshifts complement(3087654) /Source="Nicolas_upshifts" /id="U2438" /multdbtbs="-" /comp="M20" /sig="Sig-" /pcomp="0.325674325674326" /psig="0.140859140859141" /xcortree=1777 /SigmaFactorBS="tgaaaacattataccgttatggagggacaagcaatgacgcat gtacGCTTTGACTACTcaaaagcgttgactttcttcaacgaacatgaacttacatacc t" /listShort="pgi, yugM, S1195, yugN" /GFF_Attribute="listLong" misc_feature complement(3087657..3087668) /Source="Nicolas_upshift_promotors" /id="U2438" /multdbtbs="-" /comp="M20" /sig="Sig-" /pcomp="0.325674325674326" /psig="0.140859140859141" /xcortree=1777 /SigmaFactorBS="tgaaaacattataccgttatggagggacaagcaatgacgcat gtacGCTTTGACTACTcaaaagcgttgactttcttcaacgaacatgaacttacatacc t" /listShort="pgi, yugM, S1195, yugN" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" promotor_-10 complement(3087713..3087732) /Source="Nicolas_upshift_promotors" /id="U2439" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.767232767232767" /psig="0.984015984015984" /xcortree=2224 /SigmaFactorBS="aatccagtcattccgccctttcttcttgaCTTGatttcacag ataagTTCATATAAAGTGAAAGATGaaaacattataccgttatggagggacaagcaat g" /listShort="pgi, yugM, S1195, yugN" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3087719) /Source="Nicolas_upshifts" /id="U2439" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.767232767232767" /psig="0.984015984015984" /xcortree=2224 /SigmaFactorBS="aatccagtcattccgccctttcttcttgaCTTGatttcacag ataagTTCATATAAAGTGAAAGATGaaaacattataccgttatggagggacaagcaat g" /listShort="pgi, yugM, S1195, yugN" /GFF_Attribute="listLong" S_feature complement(3087721..3087792) /Source="Nicolas_S_feature" /locus_tag="new_3222123_3222194_c" /HighExp="Etha, H2O2, Paraq, Oxctl, G180, G150, dia5, dia15, G135, LBGexp" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="0.999, 0.988" /TUlongSig="SigA, SigA" /TUlongPSig="1, 1" /label="S1196" promotor_-35 complement(3087747..3087750) /Source="Nicolas_upshift_promotors" /id="U2439" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.767232767232767" /psig="0.984015984015984" /xcortree=2224 /SigmaFactorBS="aatccagtcattccgccctttcttcttgaCTTGatttcacag ataagTTCATATAAAGTGAAAGATGaaaacattataccgttatggagggacaagcaat g" /listShort="pgi, yugM, S1195, yugN" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3087793..3088965) /gene="bdhK" /locus_tag="BSU_31360" /old_locus_tag="BSU31360" /EC_number="1.1.1.-" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 1385386, 1809209, 2673038; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="NADH-dependent butanol dehydrogenase subunit" /protein_id="NP_391014.1" /db_xref="EnsemblGenomes-Gn:BSU31360" /db_xref="EnsemblGenomes-Tr:CAB15125" /db_xref="GOA:O05240" /db_xref="InterPro:IPR001670" /db_xref="InterPro:IPR018211" /db_xref="SubtiList:BG12365" /db_xref="UniProtKB/Swiss-Prot:O05240" /translation="MENFTYYNPTKLIFGKGQLEQLRKEFKRYGKNVLLVYGGGSIKR NGLYDQVTGILKEEGAVVHELSGVEPNPRLATVEKGIGLCREHDIDFLLAVGGGSVID CTKAIAAGVKYDGDAWDIFSKKVTAEDALPFGTVLTLAATGSEMNPDSVITNWETNEK FVWGSNVTHPRFSILDPENTFTVPENQTVYGMVDMMSHVFEQYFHNVENTPLQDRMCF AVLQTVIETAPKLLEDLENYELRETILYAGTIALNGTLQMGYFGDWASHTMEHAVSAV YDIPHAGGLAILFPNWMRYTLDTNVGRFKNLMLNMFDIDTEGKTDKEIALEGIDKLSA FWTSLGAPSRLADYNIGEEKLELIADIAAKEMEHGGFGNFQKLNKDDVLAILRASL*" gene complement(3087793..3088965) /gene="bdhK" /locus_tag="BSU_31360" /old_locus_tag="BSU31360" S_feature 3088128..3089049 /Source="Nicolas_S_feature" /locus_tag="new_3222530_3223451" /HighExp="S6, S7, S8, BT, S5, C30, LBGstat, B36, G135, G150" /AntisenseName="yugK" /AntisenseCor="4.31382473780575E-2" /AntisenseRegPval="-0.3" /CDS_PredictionProba="NA" /TUshortSig="NA" /TUshortPSig="NA" /TUlongSig="NA" /TUlongPSig="NA" /label="S1197" promotor_-10 complement(3088998..3089017) /Source="Nicolas_upshift_promotors" /id="U2440" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.81018981018981" /psig="0.999000999001" /xcortree=2474 /SigmaFactorBS="taaaaaaaggggaaatagccgtttggctgcttccCTTTttct tttttgtcaactTATGTTACAATGGAAAATCTgttttttaccagcatcatttggaggt t" /listShort="yugK, S1196" /listLong="pgi" /label="promotor_-10" upshifts complement(3089011) /Source="Nicolas_upshifts" /id="U2440" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.81018981018981" /psig="0.999000999001" /xcortree=2474 /SigmaFactorBS="taaaaaaaggggaaatagccgtttggctgcttccCTTTttct tttttgtcaactTATGTTACAATGGAAAATCTgttttttaccagcatcatttggaggt t" /listShort="yugK, S1196" /listLong="pgi" promotor_-35 complement(3089034..3089037) /Source="Nicolas_upshift_promotors" /id="U2440" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.81018981018981" /psig="0.999000999001" /xcortree=2474 /SigmaFactorBS="taaaaaaaggggaaatagccgtttggctgcttccCTTTttct tttttgtcaactTATGTTACAATGGAAAATCTgttttttaccagcatcatttggaggt t" /listShort="yugK, S1196" /listLong="pgi" /label="promotor_-35" CDS complement(3089069..3090232) /gene="bdhJ" /locus_tag="BSU_31370" /old_locus_tag="BSU31370" /EC_number="1.1.1.-" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 1385386, 2673038, 9643546, 11466286, 15317791; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="NADH-dependent butanol dehydrogenase" /protein_id="NP_391015.1" /db_xref="EnsemblGenomes-Gn:BSU31370" /db_xref="EnsemblGenomes-Tr:CAB15126" /db_xref="GOA:O05239" /db_xref="InterPro:IPR001670" /db_xref="InterPro:IPR018211" /db_xref="SubtiList:BG12364" /db_xref="UniProtKB/Swiss-Prot:O05239" /translation="MQNFTYWNPTKLIFGRGEVERLPEELKPYGKNVLLVYGGGSIKR SGLYDQVIEQLNKAGATVHELAGVEPNPRVSTVNKGVAICKEQNIDFLLAVGGGSVID CTKAIAAGAKYDGDAWDIVTKKHQPKDALPFGTVLTLAATGSEMNSGSVITNWETKEK YGWGSPLVFPKFSILDPVNTFTVPKNHTIYGMVDMMSHVFEQYFHHVSNTPYQDRMCE SLLRTVIETAPKLINDLENYELRETILYTGTIALNGMLSMGARGDWATHNIEHAVSAV YDIPHAGGLAILFPNWMRHTLSENPARMKQLAVRVFDVEEAGKTDEEIALEGIDKLSA FWTSLGAPNRLADYDINDEQLDTIADKAMANGTFGQFKSLNKEDVLSILKASL*" gene complement(3089069..3090232) /gene="bdhJ" /locus_tag="BSU_31370" /old_locus_tag="BSU31370" downshifts complement(3089084) /Source="Nicolas_upshifts" /id="D1626" /incds=0 /nref=167 /ntot=237 /MaxReadThrough="6.69366" /MaxDrop="4.74696" /score="28.8200012" /energy="-13.4" /TU="U2441" /idTUdmin="U2444" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(3090247..3090266) /Source="Nicolas_upshift_promotors" /id="U2441" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.803196803196803" /psig="0.988011988011988" /xcortree=1943 /SigmaFactorBS="ataaaaccatctggtatgctgatcggtgagagctgatTGCTT TACatgtggtgaggacaTTCTGCATAATAAAAAATCTaaggaggagatgtcatgcaaa a" /listShort="yugJ, yugK, S1196, pgi" /listLong="yugM, S1195, yugN" /label="promotor_-10" upshifts complement(3090265) /Source="Nicolas_upshifts" /id="U2441" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.803196803196803" /psig="0.988011988011988" /xcortree=1943 /SigmaFactorBS="ataaaaccatctggtatgctgatcggtgagagctgatTGCTT TACatgtggtgaggacaTTCTGCATAATAAAAAATCTaaggaggagatgtcatgcaaa a" /listShort="yugJ, yugK, S1196, pgi" /listLong="yugM, S1195, yugN" S_feature complement(3090267..3090422) /Source="Nicolas_S_feature" /locus_tag="new_3224669_3224824_c" /HighExp="S8, S7, S4, S5, S6, LoTm, Cold, LBGtran, G180, G135" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.25658199999999998" /TUshortSig="SigGF, SigA" /TUshortPSig="0.679, 1" /TUlongSig="SigA" /TUlongPSig=1 /label="S1198" promotor_-35 complement(3090281..3090288) /Source="Nicolas_upshift_promotors" /id="U2441" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.803196803196803" /psig="0.988011988011988" /xcortree=1943 /SigmaFactorBS="ataaaaccatctggtatgctgatcggtgagagctgatTGCTT TACatgtggtgaggacaTTCTGCATAATAAAAAATCTaaggaggagatgtcatgcaaa a" /listShort="yugJ, yugK, S1196, pgi" /listLong="yugM, S1195, yugN" /label="promotor_-35" promotor_-35 3090318..3090324 /Source="Nicolas_upshift_promotors" /id="U2442" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=195 /SigmaFactorBS="atcagctctcaccgatcagcataccagatGGTTTTAttttgc aaggtgctGGGAAAGAAGCTGATATAAgcgagggcaggccagcttccctcatatggag a" /listShort="S1199, yuzA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3090339..3090357 /Source="Nicolas_upshift_promotors" /id="U2442" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=195 /SigmaFactorBS="atcagctctcaccgatcagcataccagatGGTTTTAttttgc aaggtgctGGGAAAGAAGCTGATATAAgcgagggcaggccagcttccctcatatggag a" /listShort="S1199, yuzA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3090349 /Source="Nicolas_upshifts" /id="U2442" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=195 /SigmaFactorBS="atcagctctcaccgatcagcataccagatGGTTTTAttttgc aaggtgctGGGAAAGAAGCTGATATAAgcgagggcaggccagcttccctcatatggag a" /listShort="S1199, yuzA" /GFF_Attribute="listLong" S_feature 3090350..3090408 /Source="Nicolas_S_feature" /locus_tag="new_3224752_3224810" /HighExp="Etha, Salt, Heat, M9-stat, LPhT, Sw, Gly, BC, HiTm, B36" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigB" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S1199" promotor_-35 3090395..3090401 /Source="Nicolas_upshift_promotors" /id="U2443" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp="0.814185814185814" /psig="0.814185814185814" /xcortree=734 /SigmaFactorBS="tgatataagcgagggcaggccagcttccctcatatggagaat gcaTGTATAGattctccaatatgTCACAATCTATAactgttttaataattcatggagg a" /listShort="yuzA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(3090397..3090408) /Source="Nicolas_upshift_promotors" /id="U2444" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.679320679320679" /psig="0.679320679320679" /xcortree=897 /SigmaFactorBS="aattctttgaatggtactcatgttttgcaacctcctccatga attattaaaacaGTTATAGattgtgacatattGGAGAATCTATAcatgcattctccat a" /listShort="S1198, yugJ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3090410 /Source="Nicolas_upshifts" /id="U2443" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp="0.814185814185814" /psig="0.814185814185814" /xcortree=734 /SigmaFactorBS="tgatataagcgagggcaggccagcttccctcatatggagaat gcaTGTATAGattctccaatatgTCACAATCTATAactgttttaataattcatggagg a" /listShort="yuzA" /GFF_Attribute="listLong" promotor_-10 3090415..3090426 /Source="Nicolas_upshift_promotors" /id="U2443" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp="0.814185814185814" /psig="0.814185814185814" /xcortree=734 /SigmaFactorBS="tgatataagcgagggcaggccagcttccctcatatggagaat gcaTGTATAGattctccaatatgTCACAATCTATAactgttttaataattcatggagg a" /listShort="yuzA" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 complement(3090422..3090428) /Source="Nicolas_upshift_promotors" /id="U2444" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.679320679320679" /psig="0.679320679320679" /xcortree=897 /SigmaFactorBS="aattctttgaatggtactcatgttttgcaacctcctccatga attattaaaacaGTTATAGattgtgacatattGGAGAATCTATAcatgcattctccat a" /listShort="S1198, yugJ" /GFF_Attribute="listLong" /label="promotor_-35" upshifts complement(3090422) /Source="Nicolas_upshifts" /id="U2444" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.679320679320679" /psig="0.679320679320679" /xcortree=897 /SigmaFactorBS="aattctttgaatggtactcatgttttgcaacctcctccatga attattaaaacaGTTATAGattgtgacatattGGAGAATCTATAcatgcattctccat a" /listShort="S1198, yugJ" /GFF_Attribute="listLong" S_feature complement(3090424..3090735) /Source="Nicolas_S_feature" /locus_tag="new_3224826_3225137_c" /HighExp="Cold, LBGtran, LoTm, G180, LBGexp, dia15, G135, H2O2, Paraq, Oxctl" /AntisenseName="yuzA" /AntisenseCor="-0.50065532030853999" /AntisenseRegPval="-17.7" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="SigA" /TUlongPSig=1 /label="S1200" CDS 3090462..3090698 /gene="yuzA" /locus_tag="BSU_31380" /old_locus_tag="BSU31380" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_391016.1" /db_xref="EnsemblGenomes-Gn:BSU31380" /db_xref="EnsemblGenomes-Tr:CAB15127" /db_xref="GOA:O32087" /db_xref="InterPro:IPR007211" /db_xref="SubtiList:BG14050" /db_xref="UniProtKB/Swiss-Prot:O32087" /translation="MSTIQRICLVLTIIGAINWGLIGFFQFDLVAAIFGGQGSALSRI IYGLVGIAGLINLGLLFKPNEERSREEAANPEMR*" gene 3090462..3090698 /gene="yuzA" /locus_tag="BSU_31380" /old_locus_tag="BSU31380" downshifts 3090658 /Source="Nicolas_upshifts" /id="D1627" /incds=0 /nref=3 /ntot=45 /MaxReadThrough="7.39676" /MaxDrop="2.87922" /score="13.9936296" /energy="-12" /TU="U2442,U2443" /idTUdmin="U2442" /TUdmin="-66" /isTUend="FALSE" downshifts 3090724 /Source="Nicolas_upshifts" /id="D1628" /incds=0 /nref=25 /ntot=56 /MaxReadThrough="1.29261" /MaxDrop="7.50276" /score="13.9936296" /energy="-12" /TU="NA" /idTUdmin="U2442" /TUdmin=0 /isTUend="TRUE" CDS complement(3090776..3091168) /gene="yugI" /locus_tag="BSU_31390" /old_locus_tag="BSU31390" /function="16.6: Maintain" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 9862121, 16014871, 19152054, 19636895; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative RNA degradation protein; putative phosphorylase or nucleotidyl transferase; general stress protein" /protein_id="NP_391017.1" /db_xref="EnsemblGenomes-Gn:BSU31390" /db_xref="EnsemblGenomes-Tr:CAB15128" /db_xref="GOA:P80870" /db_xref="InterPro:IPR003029" /db_xref="InterPro:IPR012340" /db_xref="InterPro:IPR022967" /db_xref="PDB:2K4K" /db_xref="SubtiList:BG12363" /db_xref="UniProtKB/Swiss-Prot:P80870" /translation="MAAKFEVGSVYTGKVTGLQAYGAFVALDEETQGLVHISEVTHGF VKDINEHLSVGDEVQVKVLAVDEEKGKISLSIRATQAAPEKKESKPRKPKAAQVSEEA STPQGFNTLKDKLEEWIEMSNRKDLIKK*" gene complement(3090776..3091168) /gene="yugI" /locus_tag="BSU_31390" /old_locus_tag="BSU31390" downshifts complement(3090780) /Source="Nicolas_upshifts" /id="D1629" /incds=0 /nref=232 /ntot=268 /MaxReadThrough="5.9665" /MaxDrop="6.0195" /score="13.5952751" /energy="-15.6" /TU="U2445" /idTUdmin="U2448" /TUdmin="-2" /isTUend="TRUE" promotor_-10 complement(3091210..3091229) /Source="Nicolas_upshift_promotors" /id="U2445" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.921078921078921" /psig=1 /xcortree=2503 /SigmaFactorBS="taaacctgattttttataaaaaagttttCTTTGcggaaataa gacatgTGTGATATAATTTTAAATTGcgtataaacagatatttaatttaacttaggag t" /listShort="yugI, S1200, S1198, yugJ" /listLong="yugK, S1196, pgi, yugM" /label="promotor_-10" upshifts complement(3091217) /Source="Nicolas_upshifts" /id="U2445" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.921078921078921" /psig=1 /xcortree=2503 /SigmaFactorBS="taaacctgattttttataaaaaagttttCTTTGcggaaataa gacatgTGTGATATAATTTTAAATTGcgtataaacagatatttaatttaacttaggag t" /listShort="yugI, S1200, S1198, yugJ" /listLong="yugK, S1196, pgi, yugM" S_feature complement(3091219..3091369) /Source="Nicolas_S_feature" /locus_tag="new_3225621_3225771_c" /HighExp="G180, C30, G135, LBGexp, G150, Oxctl, HPh, Cold, BMM, LPh" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1201" promotor_-35 complement(3091245..3091249) /Source="Nicolas_upshift_promotors" /id="U2445" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.921078921078921" /psig=1 /xcortree=2503 /SigmaFactorBS="taaacctgattttttataaaaaagttttCTTTGcggaaataa gacatgTGTGATATAATTTTAAATTGcgtataaacagatatttaatttaacttaggag t" /listShort="yugI, S1200, S1198, yugJ" /listLong="yugK, S1196, pgi, yugM" /label="promotor_-35" promotor_-35 3091272..3091278 /Source="Nicolas_upshift_promotors" /id="U2446" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.662337662337662" /psig="0.662337662337662" /xcortree=1396 /SigmaFactorBS="tcacacatgtcttatttccgcaaagaaaacttttttataaaa aatcaGGTTTATgcacagcaaaaaggGGGTAAACTGAAAATACCAaaggctttctagt a" /listShort="S1202" /GFF_Attribute="listLong" /label="promotor_-35" S_feature 3091285..3092269 /Source="Nicolas_S_feature" /locus_tag="new_3225687_3226671" /HighExp="LoTm, C30, Salt, S7, S5, S8, Sw, S3, C90, S6" /AntisenseName="yugH" /AntisenseCor="-0.45629591209076698" /AntisenseRegPval="-14.5" /CDS_PredictionProba="NA" /TUshortSig="SigB" /TUshortPSig="0.662" /TUlongSig="NA" /TUlongPSig="NA" /label="S1202" upshifts 3091285 /Source="Nicolas_upshifts" /id="U2446" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.662337662337662" /psig="0.662337662337662" /xcortree=1396 /SigmaFactorBS="tcacacatgtcttatttccgcaaagaaaacttttttataaaa aatcaGGTTTATgcacagcaaaaaggGGGTAAACTGAAAATACCAaaggctttctagt a" /listShort="S1202" /GFF_Attribute="listLong" promotor_-10 3091293..3091311 /Source="Nicolas_upshift_promotors" /id="U2446" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.662337662337662" /psig="0.662337662337662" /xcortree=1396 /SigmaFactorBS="tcacacatgtcttatttccgcaaagaaaacttttttataaaa aatcaGGTTTATgcacagcaaaaaggGGGTAAACTGAAAATACCAaaggctttctagt a" /listShort="S1202" /GFF_Attribute="listLong" /label="promotor_-10" CDS complement(3091370..3092530) /gene="yugH" /locus_tag="BSU_31400" /old_locus_tag="BSU31400" /EC_number="2.6.1.-" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 12670965; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative aspartate aminotransferase" /protein_id="NP_391018.2" /db_xref="EnsemblGenomes-Gn:BSU31400" /db_xref="EnsemblGenomes-Tr:CAB15129" /db_xref="GOA:Q795M6" /db_xref="InterPro:IPR004838" /db_xref="InterPro:IPR004839" /db_xref="InterPro:IPR015421" /db_xref="InterPro:IPR015422" /db_xref="InterPro:IPR015424" /db_xref="SubtiList:BG12362" /db_xref="UniProtKB/Swiss-Prot:Q795M6" /translation="MTSYLSDYVQQIKPSGIRKFFDLAATMEGVISLGVGEPDFVTAW NVREASILSLEQGYTSYTANAGLYSLREEISRYLSNRFDLSYSPDNELIVTVGASQAL DIAIRAIVNPGEEVIIPEPCFVAYDALVSLAGGIPVHVHTTADKGFKATAADFEAAVT EKTKAILICSPSNPTGSVYSKEELNEIAEFAKKHDVIVLADEIYAELTYDEEFTSIAA LPGMKERTVVISGFSKAFAMTGWRLGFAAAPSLLRDAMLKIHQYAMMCAPAMAQFAAL EGLKNGMEDVEKMKKSYRRRRNLFVESLNEIGLSCHHPGGAFYAFPSIKSMGMSSEQF AEELLTQEKVAVVPGSVFGPSGEGYIRCSYATSIEQLQEALVRMKRFLHKTT*" gene complement(3091370..3092530) /gene="yugH" /locus_tag="BSU_31400" /old_locus_tag="BSU31400" promotor_-35 3092422..3092428 /Source="Nicolas_upshift_promotors" /id="U2447" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.964035964035964" /psig="0.003996003996004" /xcortree=33 /SigmaFactorBS="tgcttgcttcgcggacattccatgcggtaacaaaatcaggct CGCCGACgcctaaagaaatgACGCCttccatcgttgccgccaaatcaaagaatttgcg g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 3092440 /Source="Nicolas_upshifts" /id="U2447" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.964035964035964" /psig="0.003996003996004" /xcortree=33 /SigmaFactorBS="tgcttgcttcgcggacattccatgcggtaacaaaatcaggct CGCCGACgcctaaagaaatgACGCCttccatcgttgccgccaaatcaaagaatttgcg g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 3092442..3092446 /Source="Nicolas_upshift_promotors" /id="U2447" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.964035964035964" /psig="0.003996003996004" /xcortree=33 /SigmaFactorBS="tgcttgcttcgcggacattccatgcggtaacaaaatcaggct CGCCGACgcctaaagaaatgACGCCttccatcgttgccgccaaatcaaagaatttgcg g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" CDS complement(3092531..3093031) /gene="yugG" /locus_tag="BSU_31410" /old_locus_tag="BSU31410" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative transcriptional regulator (Lrp/AsnC family)" /protein_id="NP_391019.1" /db_xref="EnsemblGenomes-Gn:BSU31410" /db_xref="EnsemblGenomes-Tr:CAB15130" /db_xref="GOA:O05236" /db_xref="InterPro:IPR000485" /db_xref="InterPro:IPR011008" /db_xref="InterPro:IPR019887" /db_xref="InterPro:IPR019888" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG12361" /db_xref="UniProtKB/Swiss-Prot:O05236" /translation="MKLTEKETEILEILDENSRADLETIAKMAGIPVNEVKTIIDKLE KEKVIIDYSAMIDWRKVDGHEGVTAMIDVKVTPKRGVGFDEVAERIYRFQEVESVYLM SGVYDLSVVIRGNSMSDVARFVSDKLSTLDSVVSTTTHFILKKYKHDGKVFETGDDDK RIVVSP*" gene complement(3092531..3093031) /gene="yugG" /locus_tag="BSU_31410" /old_locus_tag="BSU31410" promotor_-10 complement(3093061..3093080) /Source="Nicolas_upshift_promotors" /id="U2448" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.996003996003996" /psig=1 /xcortree=2242 /SigmaFactorBS="ccctgaaattgtcaattctagcggaagtttctcctcgttttt tcTTAGCATTcgtcaaaaaaCGTGATATAATGTCATGAGAtttcttgacattgcaaag g" /listShort="yugG, yugH, S1201, yugI" /listLong="S1200, S1198, yugJ, yugK, S1196, pgi, yugM" /label="promotor_-10" promotor_-35 3093067..3093073 /Source="Nicolas_upshift_promotors" /id="U2449" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=876 /SigmaFactorBS="tcatttgattcacacctttgcaatgtcaagaaatctcatGAC ATTAtatcacgttttttgACGAATGCTAAGaaaaaacgaggagaaacttccgctagaa t" /listShort="S1203, yugF" /GFF_Attribute="listLong" /label="promotor_-35" upshifts complement(3093082) /Source="Nicolas_upshifts" /id="U2448" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.996003996003996" /psig=1 /xcortree=2242 /SigmaFactorBS="ccctgaaattgtcaattctagcggaagtttctcctcgttttt tcTTAGCATTcgtcaaaaaaCGTGATATAATGTCATGAGAtttcttgacattgcaaag g" /listShort="yugG, yugH, S1201, yugI" /listLong="S1200, S1198, yugJ, yugK, S1196, pgi, yugM" promotor_-10 3093088..3093099 /Source="Nicolas_upshift_promotors" /id="U2449" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=876 /SigmaFactorBS="tcatttgattcacacctttgcaatgtcaagaaatctcatGAC ATTAtatcacgttttttgACGAATGCTAAGaaaaaacgaggagaaacttccgctagaa t" /listShort="S1203, yugF" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3093088 /Source="Nicolas_upshifts" /id="U2449" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=876 /SigmaFactorBS="tcatttgattcacacctttgcaatgtcaagaaatctcatGAC ATTAtatcacgttttttgACGAATGCTAAGaaaaaacgaggagaaacttccgctagaa t" /listShort="S1203, yugF" /GFF_Attribute="listLong" promotor_-35 complement(3093091..3093098) /Source="Nicolas_upshift_promotors" /id="U2448" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.996003996003996" /psig=1 /xcortree=2242 /SigmaFactorBS="ccctgaaattgtcaattctagcggaagtttctcctcgttttt tcTTAGCATTcgtcaaaaaaCGTGATATAATGTCATGAGAtttcttgacattgcaaag g" /listShort="yugG, yugH, S1201, yugI" /listLong="S1200, S1198, yugJ, yugK, S1196, pgi, yugM" /label="promotor_-35" S_feature 3093100..3093178 /Source="Nicolas_S_feature" /locus_tag="new_3227502_3227580" /HighExp="S8, S5, S6, S7, S4, C30, Glucon, Pyr, nit, ferm" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigGF" /TUshortPSig="0.998" /TUlongSig="NA" /TUlongPSig="NA" /label="S1203" CDS 3093179..3094000 /gene="yugF" /locus_tag="BSU_31420" /old_locus_tag="BSU31420" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative hydrolase" /protein_id="NP_391020.1" /db_xref="EnsemblGenomes-Gn:BSU31420" /db_xref="EnsemblGenomes-Tr:CAB15131" /db_xref="GOA:O05235" /db_xref="InterPro:IPR000073" /db_xref="InterPro:IPR000639" /db_xref="InterPro:IPR013595" /db_xref="InterPro:IPR029058" /db_xref="SubtiList:BG12360" /db_xref="UniProtKB/Swiss-Prot:O05235" /translation="MEAVSPIRRFTVDGVNVYYEHYQNPGRQTLVCVHGFLSSAFSFR KVIPLLRDKYDIIALDLPPFGQSEKSRTFIYTYQNLAKLVIGILEHLQVKQAVLVGHS MGGQISLSAALQKPELFSKVVLLCSSGYLKRSHPTIIFGTHIPYFHLYIKRWLSKEGV MKNLLNVVHDKSLIDEEMIDGYGRPFQDEQIFKAMTRFIRHREGDLEPEQLKKMNKPA LLIWGEEDRIVPMEIGKRLHADLPNSVLYSLGQTGHLVPEERPELISEHIADFIK*" gene 3093179..3094000 /gene="yugF" /locus_tag="BSU_31420" /old_locus_tag="BSU31420" downshifts 3093980 /Source="Nicolas_upshifts" /id="D1630" /incds=0 /nref=1 /ntot=12 /MaxReadThrough="1.0929" /MaxDrop="3.08755" /score="11.2614618" /energy="-6.6" /TU="NA" /idTUdmin="U2449" /TUdmin=0 /isTUend="TRUE" downshifts complement(3094027) /Source="Nicolas_upshifts" /id="D1631" /incds=0 /nref=20 /ntot=156 /MaxReadThrough="2.22671" /MaxDrop="4.10906" /score="25.9859375" /energy="-6.6" /TU="NA" /idTUdmin="U2451" /TUdmin=7 /isTUend="TRUE" CDS complement(3094029..3094289) /gene="yugE" /locus_tag="BSU_31430" /old_locus_tag="BSU31430" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_391021.2" /db_xref="EnsemblGenomes-Gn:BSU31430" /db_xref="EnsemblGenomes-Tr:CAB15132" /db_xref="InterPro:IPR015053" /db_xref="InterPro:IPR023162" /db_xref="SubtiList:BG12359" /db_xref="UniProtKB/Swiss-Prot:O05234" /translation="MEESHAVREMIKIIAKWDPFKYGEEFYETEAVDVVQAVYDENDP DLLAKSIQQIFETSFEQTLPIASCREVAGQLLFIKNSSSCTP*" gene complement(3094029..3094289) /gene="yugE" /locus_tag="BSU_31430" /old_locus_tag="BSU31430" promotor_-35 3094279..3094282 /Source="Nicolas_upshift_promotors" /id="U2450" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.512487512487512" /psig="0.996003996003996" /xcortree=2691 /SigmaFactorBS="atgatcttaatcatttccctgaccgcatgaCTTTcttccata ttcatcACCGCTTATAATAAAATTTGcagttctatcttatcatagtgaagcttagaag a" /listShort="S1204, patB, kinB" /listLong="kapB" /label="promotor_-35" promotor_-10 3094297..3094316 /Source="Nicolas_upshift_promotors" /id="U2450" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.512487512487512" /psig="0.996003996003996" /xcortree=2691 /SigmaFactorBS="atgatcttaatcatttccctgaccgcatgaCTTTcttccata ttcatcACCGCTTATAATAAAATTTGcagttctatcttatcatagtgaagcttagaag a" /listShort="S1204, patB, kinB" /listLong="kapB" /label="promotor_-10" upshifts 3094309 /Source="Nicolas_upshifts" /id="U2450" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.512487512487512" /psig="0.996003996003996" /xcortree=2691 /SigmaFactorBS="atgatcttaatcatttccctgaccgcatgaCTTTcttccata ttcatcACCGCTTATAATAAAATTTGcagttctatcttatcatagtgaagcttagaag a" /listShort="S1204, patB, kinB" /listLong="kapB" S_feature 3094310..3094375 /Source="Nicolas_S_feature" /locus_tag="new_3228712_3228777" /HighExp="dia15, dia5, Lbexp, dia0, LBGtran, G180, Diami, H2O2, G150, Oxctl" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.996" /TUlongSig="NA" /TUlongPSig="NA" /label="S1204" promotor_-10 complement(3094315..3094334) /Source="Nicolas_upshift_promotors" /id="U2451" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.883116883116883" /psig=1 /xcortree=2500 /SigmaFactorBS="ttcattctgttaccccctcatgtatgttTATTCTTctaagct tcacTATGATAAGATAGAACTGCAaattttattataagcggtgatgaatatggaagaa a" /listShort="yugE" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3094320) /Source="Nicolas_upshifts" /id="U2451" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.883116883116883" /psig=1 /xcortree=2500 /SigmaFactorBS="ttcattctgttaccccctcatgtatgttTATTCTTctaagct tcacTATGATAAGATAGAACTGCAaattttattataagcggtgatgaatatggaagaa a" /listShort="yugE" /GFF_Attribute="listLong" promotor_-35 complement(3094346..3094352) /Source="Nicolas_upshift_promotors" /id="U2451" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.883116883116883" /psig=1 /xcortree=2500 /SigmaFactorBS="ttcattctgttaccccctcatgtatgttTATTCTTctaagct tcacTATGATAAGATAGAACTGCAaattttattataagcggtgatgaatatggaagaa a" /listShort="yugE" /GFF_Attribute="listLong" /label="promotor_-35" CDS 3094376..3095539 /gene="patB" /locus_tag="BSU_31440" /old_locus_tag="BSU31440" /EC_number="4.4.1.1" /EC_number="4.4.1.13" /EC_number="4.4.1.8" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:15760717, 26337367, 28895253" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15760717, 26337367, 28895253; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="promiscuous cystathionine / cystine beta-lyase /cysteine desulfhydrase" /protein_id="NP_391022.1" /db_xref="EnsemblGenomes-Gn:BSU31440" /db_xref="EnsemblGenomes-Tr:CAB15133" /db_xref="GOA:Q08432" /db_xref="InterPro:IPR004839" /db_xref="InterPro:IPR015421" /db_xref="InterPro:IPR015422" /db_xref="InterPro:IPR015424" /db_xref="InterPro:IPR027619" /db_xref="SubtiList:BG10744" /db_xref="UniProtKB/Swiss-Prot:Q08432" /translation="MNFDKREERLGTQSVKWDKTGELFGVTDALPMWVADMDFRAPEA ITEALKERLDHGIFGYTTPDQKTKDAVCGWMQNRHGWKVNPESITFSPGVVTALSMAV QAFTEPGDQVVVQPPVYTPFYHMVEKNGRHILHNPLLEKDGAYAIDFEDLETKLSDPS VTLFILCNPHNPSGRSWSREDLLKLGELCLEHGVTVVSDEIHSDLMLYGHKHTPFASL SDDFADISVTCAAPSKTFNIAGLQASAIIIPDRLKRAKFSASLQRNGLGGLNAFAVTA IEAAYSKGGPWLDELITYIEKNMNEAEAFLSTELPKVKMMKPDASYLIWLDFSAYGLS DAELQQRMLKKGKVILEPGTKYGPGGEGFMRLNAGCSLATLQDGLRRIKAALS*" gene 3094376..3095539 /gene="patB" /locus_tag="BSU_31440" /old_locus_tag="BSU31440" promotor_-35 3095602..3095608 /Source="Nicolas_upshift_promotors" /id="U2452" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.852147852147852" /psig="0.999000999001" /xcortree=3054 /SigmaFactorBS="ttgtaaaggcgttcttaataaaggaattttatATTTTACttc taatatttAGTGTTATAATAGATTCATAttttatacgaaaggatttcacacgaatgga a" /listShort="kinB, kapB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3095620..3095639 /Source="Nicolas_upshift_promotors" /id="U2452" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.852147852147852" /psig="0.999000999001" /xcortree=3054 /SigmaFactorBS="ttgtaaaggcgttcttaataaaggaattttatATTTTACttc taatatttAGTGTTATAATAGATTCATAttttatacgaaaggatttcacacgaatgga a" /listShort="kinB, kapB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3095630 /Source="Nicolas_upshifts" /id="U2452" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.852147852147852" /psig="0.999000999001" /xcortree=3054 /SigmaFactorBS="ttgtaaaggcgttcttaataaaggaattttatATTTTACttc taatatttAGTGTTATAATAGATTCATAttttatacgaaaggatttcacacgaatgga a" /listShort="kinB, kapB" /GFF_Attribute="listLong" CDS 3095665..3096951 /gene="kinB" /locus_tag="BSU_31450" /old_locus_tag="BSU31450" /EC_number="2.7.13.3" /function="16.12: Sense" /experiment="publication(s) with functional evidences, PMID:9426145, 11069677, 15849754, 16850406, 26152584, 28583948" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9426145, 11069677, 15849754, 16850406, 26152584, 28583948; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="two-component sensor potassium-binding histidinekinase" /protein_id="NP_391023.2" /db_xref="EnsemblGenomes-Gn:BSU31450" /db_xref="EnsemblGenomes-Tr:CAB15134" /db_xref="GOA:Q08430" /db_xref="InterPro:IPR003594" /db_xref="InterPro:IPR003661" /db_xref="InterPro:IPR004358" /db_xref="InterPro:IPR005467" /db_xref="InterPro:IPR036097" /db_xref="InterPro:IPR036890" /db_xref="SubtiList:BG10745" /db_xref="UniProtKB/Swiss-Prot:Q08430" /translation="MEILKDYLLHICFILFPILLYQVFWLGKPAILVPKINSGLVTLF ACGASVLCIIFPIHEMDYIQYGLQMIPVIICLFYISTASGLTVAASVLCFELLFYEPS AMFVFTLLPFLIIIPILFQKKWPFMSKAKKLLLSLLISCVEIFLFFASSWILSALNIL NFQKSGIFVYEAAVSGLFRSSVLLLSIYIIESIAENIALRSQLIHSEKMTIVSELAAS VAHEVRNPLTVVRGFVQLLFNDETLQNKSSADYKKLVLSELDRAQGIITNYLDMAKQQ LYEKEVFDLSALIKETSSLMVSYANYKSVTVEAETEPDLLIYGDATKLKQAVINLMKN SIEAVPHGKGMIHISAKRNGHTIMINITDNGVGMTDHQMQKLGEPYYSLKTNGTGLGL TVTFSIIEHHHGTISFNSSFQKGTTVTIKLPADLPH*" gene 3095665..3096951 /gene="kinB" /locus_tag="BSU_31450" /old_locus_tag="BSU31450" S_feature complement(3096667..3097409) /Source="Nicolas_S_feature" /locus_tag="new_3231069_3231811_c" /HighExp="BT, S8, B36, S6, S7, S5, S3, S4, Cold, Pyr" /AntisenseName="kapB" /AntisenseCor="-0.71681066342113797" /AntisenseRegPval="-43" /CDS_PredictionProba="NA" /TUshortSig="SigEF, SigK" /TUshortPSig="0.709, 0.985" /TUlongSig="NA" /TUlongPSig="NA" /label="S1205" promotor_-35 3096946..3096953 /Source="Nicolas_upshift_promotors" /id="U2453" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.679320679320679" /psig="0.986013986013986" /xcortree=2010 /SigmaFactorBS="gcactacggtgaccattaagcttcccgctgatcttcctCACT AGCAaatcgattggaacTTTAATAGAATAAATGCGAGgtgatgacagatgagcacgtt t" /listShort="kapB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3096967..3096986 /Source="Nicolas_upshift_promotors" /id="U2453" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.679320679320679" /psig="0.986013986013986" /xcortree=2010 /SigmaFactorBS="gcactacggtgaccattaagcttcccgctgatcttcctCACT AGCAaatcgattggaacTTTAATAGAATAAATGCGAGgtgatgacagatgagcacgtt t" /listShort="kapB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3096968 /Source="Nicolas_upshifts" /id="U2453" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.679320679320679" /psig="0.986013986013986" /xcortree=2010 /SigmaFactorBS="gcactacggtgaccattaagcttcccgctgatcttcctCACT AGCAaatcgattggaacTTTAATAGAATAAATGCGAGgtgatgacagatgagcacgtt t" /listShort="kapB" /GFF_Attribute="listLong" CDS 3096997..3097383 /gene="kapB" /locus_tag="BSU_31460" /old_locus_tag="BSU31460" /function="16.3: Control" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:9426145, 23335417" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9426145, 23335417; Product type f: factor" /codon_start=1 /transl_table=11 /product="factor required for KinB signal transduction andactivation of the phosphorelay to sporulation" /protein_id="NP_391024.1" /db_xref="EnsemblGenomes-Gn:BSU31460" /db_xref="EnsemblGenomes-Tr:CAB15135" /db_xref="GOA:Q08429" /db_xref="InterPro:IPR014916" /db_xref="SubtiList:BG10746" /db_xref="UniProtKB/Swiss-Prot:Q08429" /translation="MSTFETGSIVKGFYKTGVYIGEITACRPQHYLVKVKAVLTHPAQ GDLHHPKQADVPFFHERKALAYGEQTNIPHHMVKPYDGEVPDYTESLREATAQMRAKL NEDGSEWAKRSLHNLDILEKEYFNRP*" gene 3096997..3097383 /gene="kapB" /locus_tag="BSU_31460" /old_locus_tag="BSU31460" downshifts 3097365 /Source="Nicolas_upshifts" /id="D1632" /incds=0 /nref=209 /ntot=249 /MaxReadThrough="1.62013" /MaxDrop="5.57132" /score="1.97959632" /energy="-9.2" /TU="NA" /idTUdmin="U2452" /TUdmin=0 /isTUend="TRUE" CDS complement(3097410..3098027) /gene="kapD" /locus_tag="BSU_31470" /old_locus_tag="BSU31470" /EC_number="3.1.-.-" /function="16.3: Control" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 27188294; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative exoribonuclease (3'-5')" /protein_id="NP_391025.1" /db_xref="EnsemblGenomes-Gn:BSU31470" /db_xref="EnsemblGenomes-Tr:CAB15136" /db_xref="GOA:O05231" /db_xref="InterPro:IPR012337" /db_xref="InterPro:IPR013520" /db_xref="InterPro:IPR036397" /db_xref="SubtiList:BG12358" /db_xref="UniProtKB/Swiss-Prot:O05231" /translation="MTTNSLLIIDFEFTMPDGKYSPQNFFPEIIEAGIVKSIDDEVVE TFSSYVRPKKFPKLTKRCKSFLKITQKQVDEGMRFEDFIRKLNELDPEKNSTIITWGN MDMKVLKQNCMFNHIPFPFKGEMRDLSLEYKNFFGDRTLTGLWKAAEEYGDSGTGTHH KALDDALTAYKLFKLVEQDKQYLEKPKPPTIGERIDLTELLKRAT*" gene complement(3097410..3098027) /gene="kapD" /locus_tag="BSU_31470" /old_locus_tag="BSU31470" promotor_-10 complement(3098062..3098080) /Source="Nicolas_upshift_promotors" /id="U2454" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.709290709290709" /psig="0.709290709290709" /xcortree=1399 /SigmaFactorBS="cgaagcggctgggaaaattcattatttttagaaaatgaaGAA ATGtcgagaaggggaatTGATATACTATAAAGATAGcattttctgatcggaggaaagg c" /listShort="kapD, S1205" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3098079) /Source="Nicolas_upshifts" /id="U2454" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.709290709290709" /psig="0.709290709290709" /xcortree=1399 /SigmaFactorBS="cgaagcggctgggaaaattcattatttttagaaaatgaaGAA ATGtcgagaaggggaatTGATATACTATAAAGATAGcattttctgatcggaggaaagg c" /listShort="kapD, S1205" /GFF_Attribute="listLong" S_feature complement(3098081..3100169) /Source="Nicolas_S_feature" /locus_tag="new_3232483_3234571_c" /HighExp="S8, BT, B36, S7, S6, Pyr, C30, B60, S5, G135" /AntisenseName="yuxJ" /AntisenseCor="-0.168930816447634" /AntisenseRegPval="-2.2999999999999998" /CDS_PredictionProba="NA" /TUshortSig="SigK" /TUshortPSig="0.985" /TUlongSig="NA" /TUlongPSig="NA" /label="S1206" promotor_-35 complement(3098095..3098100) /Source="Nicolas_upshift_promotors" /id="U2454" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.709290709290709" /psig="0.709290709290709" /xcortree=1399 /SigmaFactorBS="cgaagcggctgggaaaattcattatttttagaaaatgaaGAA ATGtcgagaaggggaatTGATATACTATAAAGATAGcattttctgatcggaggaaagg c" /listShort="kapD, S1205" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 3098143..3098146 /Source="Nicolas_upshift_promotors" /id="U2455" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.561438561438561" /psig=1 /xcortree=1539 /SigmaFactorBS="aaaataatgaattttcccagccgcttcgtttCTTTtaaattg tgaatcgTTTCTTTATAATTAGTAAGGaacccgaaataataagaaggtgatgttattt c" /listShort="yuxJ" /listLong="pbpD, yuxK" /label="promotor_-35" promotor_-10 3098161..3098180 /Source="Nicolas_upshift_promotors" /id="U2455" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.561438561438561" /psig=1 /xcortree=1539 /SigmaFactorBS="aaaataatgaattttcccagccgcttcgtttCTTTtaaattg tgaatcgTTTCTTTATAATTAGTAAGGaacccgaaataataagaaggtgatgttattt c" /listShort="yuxJ" /listLong="pbpD, yuxK" /label="promotor_-10" upshifts 3098172 /Source="Nicolas_upshifts" /id="U2455" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.561438561438561" /psig=1 /xcortree=1539 /SigmaFactorBS="aaaataatgaattttcccagccgcttcgtttCTTTtaaattg tgaatcgTTTCTTTATAATTAGTAAGGaacccgaaataataagaaggtgatgttattt c" /listShort="yuxJ" /listLong="pbpD, yuxK" CDS 3098238..3099416 /gene="yuxJ" /locus_tag="BSU_31480" /old_locus_tag="BSU31480" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406, 20011599; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative exporter induced in acid stress" /protein_id="NP_391026.2" /db_xref="EnsemblGenomes-Gn:BSU31480" /db_xref="EnsemblGenomes-Tr:CAB15137" /db_xref="GOA:P40760" /db_xref="InterPro:IPR001958" /db_xref="InterPro:IPR011701" /db_xref="InterPro:IPR020846" /db_xref="InterPro:IPR036259" /db_xref="SubtiList:BG10976" /db_xref="UniProtKB/Swiss-Prot:P40760" /translation="MWLANFFVSASTTMIVPFLSLYIETLSSFSNGFVQRWSGYVFGI TFLMAFLVSPFWGRFGDKRGYKKILMATGTGIALSIFFMGFVTSVYQLFFLRMAMGLV TGFIPTSLAMISAQTPKSSAGKTLGTLQMGQVSGSLFGPLLGGMLADRFGFTYTFFIT SFVIFSSVLLVLFGVKEKHLAEKTAKRTSYSRKEVLSYIFHHPALWVMMLLTMLIQTG NFSIQPLLALYVNELHGPVNLAFFSGMAFSATGLGSLLLARKWGDLGDRYGHRRILIG LLLAASFFFIPQALASSLSVLLVFRFLFGMAMGGLLPCITAAIRVQAPGSIQGEVLGY NVSFRFLGNVLGPLLGGIISSHFTISATFYVTAFLFFAGACMLWIMQKLRKDSYAKAS *" gene 3098238..3099416 /gene="yuxJ" /locus_tag="BSU_31480" /old_locus_tag="BSU31480" promotor_-35 3099454..3099460 /Source="Nicolas_upshift_promotors" /id="U2456" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.976023976023976" /psig=1 /xcortree=2246 /SigmaFactorBS="ttccgagaaaaaactaaggaatcttctaaatttaaccTTCTC GTaatctcaaaagAATGGTACGATATGGCTAGAatttaggagaaaagagagtgaccat g" /listShort="pbpD, yuxK" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3099472..3099491 /Source="Nicolas_upshift_promotors" /id="U2456" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.976023976023976" /psig=1 /xcortree=2246 /SigmaFactorBS="ttccgagaaaaaactaaggaatcttctaaatttaaccTTCTC GTaatctcaaaagAATGGTACGATATGGCTAGAatttaggagaaaagagagtgaccat g" /listShort="pbpD, yuxK" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3099477 /Source="Nicolas_upshifts" /id="U2456" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.976023976023976" /psig=1 /xcortree=2246 /SigmaFactorBS="ttccgagaaaaaactaaggaatcttctaaatttaaccTTCTC GTaatctcaaaagAATGGTACGATATGGCTAGAatttaggagaaaagagagtgaccat g" /listShort="pbpD, yuxK" /GFF_Attribute="listLong" CDS 3099509..3101383 /gene="pbpD" /locus_tag="BSU_31490" /old_locus_tag="BSU31490" /EC_number="2.-.-.-" /function="16.13: Shape" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 7961491, 9274030; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="penicillin-binding protein 4" /protein_id="NP_391027.2" /db_xref="EnsemblGenomes-Gn:BSU31490" /db_xref="EnsemblGenomes-Tr:CAB15138" /db_xref="GOA:P40750" /db_xref="InterPro:IPR001264" /db_xref="InterPro:IPR001460" /db_xref="InterPro:IPR012338" /db_xref="InterPro:IPR023346" /db_xref="InterPro:IPR036950" /db_xref="SubtiList:BG10977" /db_xref="UniProtKB/Swiss-Prot:P40750" /translation="MTMLRKIIGWILLLCIIPLFAFTVIASGKEVKQMKSLDQVLDKN IDLKDISLVQNSYMYDRDGSLVSEIVSDHENRVLVPFNKIPEEVKQIFLTSEDRHFYE HKGFDFMGMVRATASNVKDKKIDQGASTITQQLSRNLYLSHERSFSRKLTELAYSYQL EKKYTKNEILEAYLNTIYFNNGVYGVGSAAQFYFSKPLKSLTVGEMAFICAIPNNPTL YDPLKHFDYTKSRQERLLKGLKDAGVITDKELKKAVKQKIKLDVEKREDKYPDYVSYV NDEFTQLVSESEGFDKRLQKASGKQKEKIENELSARVSTLMKDGVKIYTALDPYMQNQ VVAQMNSKLPYADVQGGAAVINHQTHQIIALSGGKNYQKYDFNRAYQAYRQPGSSIKP LLDYGPYIEQTGATTSSTIDASKFCSKDYCPQNYNNRTYGTVTLDTAFKNSYNTPAIR MLDRVGIQKAFSYIEPYHFAKLVDSDYLLPAALGGFTNGMTPLEMTKAYTTFGNSGSY TPSHAITKVTDLKGKTLYKWNDKATQIFSVRTNMQLKKLMSSVVKSGTGKKAYFNAPY IGGKTGTSNDYHDMWFVGLTDTYTMGVWVGKDTPTSVEYLHSISPQLSIWKGTLQAAY *" gene 3099509..3101383 /gene="pbpD" /locus_tag="BSU_31490" /old_locus_tag="BSU31490" promotor_-10 complement(3100149..3100168) /Source="Nicolas_upshift_promotors" /id="U2457" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.985014985014985" /psig="0.985014985014985" /xcortree=1344 /SigmaFactorBS="cttttagccctttaagtaaacgttcttgacggcttttcGTGT AGTCAAaatgcttgagaggATCATATAATGTAGGGTTATtaggtatagcacagataaa a" /listShort="S1206, kapD, S1205" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3100169) /Source="Nicolas_upshifts" /id="U2457" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.985014985014985" /psig="0.985014985014985" /xcortree=1344 /SigmaFactorBS="cttttagccctttaagtaaacgttcttgacggcttttcGTGT AGTCAAaatgcttgagaggATCATATAATGTAGGGTTATtaggtatagcacagataaa a" /listShort="S1206, kapD, S1205" /GFF_Attribute="listLong" promotor_-35 complement(3100182..3100191) /Source="Nicolas_upshift_promotors" /id="U2457" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.985014985014985" /psig="0.985014985014985" /xcortree=1344 /SigmaFactorBS="cttttagccctttaagtaaacgttcttgacggcttttcGTGT AGTCAAaatgcttgagaggATCATATAATGTAGGGTTATtaggtatagcacagataaa a" /listShort="S1206, kapD, S1205" /GFF_Attribute="listLong" /label="promotor_-35" CDS 3101404..3101817 /gene="yuxK" /locus_tag="BSU_31500" /old_locus_tag="BSU31500" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 26335199; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative thiol-disulfide oxidoreductase" /protein_id="NP_391028.1" /db_xref="EnsemblGenomes-Gn:BSU31500" /db_xref="EnsemblGenomes-Tr:CAB15139" /db_xref="InterPro:IPR007263" /db_xref="SubtiList:BG10978" /db_xref="UniProtKB/Swiss-Prot:P40761" /translation="MTSEQIPNRVLLFDGVCNLCNGAVQFIIKRDPDGLISFTSLQSE TGQSLLKKSGLPTDRFDSFVFIEDGQVYTKSTAAIKVFRHLRGPWRLFVLFFAVPKPV RDMVYSFIAKNRYKWFGKKNECMLPSPSIKKRFLP*" gene 3101404..3101817 /gene="yuxK" /locus_tag="BSU_31500" /old_locus_tag="BSU31500" downshifts 3101809 /Source="Nicolas_upshifts" /id="D1633" /incds=0 /nref=1 /ntot=254 /MaxReadThrough="5.05064" /MaxDrop="3.14634" /score="-3.58105315" /energy="-11.5" /TU="U2456" /idTUdmin="U2456" /TUdmin="-22" /isTUend="TRUE" CDS complement(3102020..3102577) /gene="yufK" /locus_tag="BSU_31510" /old_locus_tag="BSU31510" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative integral membrane protein" /protein_id="NP_391029.2" /db_xref="EnsemblGenomes-Gn:BSU31510" /db_xref="EnsemblGenomes-Tr:CAB15140" /db_xref="GOA:O05249" /db_xref="InterPro:IPR035289" /db_xref="SubtiList:BG12346" /db_xref="UniProtKB/Swiss-Prot:O05249" /translation="MKNTYLTGYFPLIAILLFSSSLSISTSLYALKMLSSFGMYDGML DYFSEKGIRLALFAAFALLYFMVLSALKLIANTVTELSLLFFANDPEGNNLKKLRMGS MIYLGGGILSFVLLQNVIWIVIWFAVVTLAYFVFTVYRIYSTLSLMSLVGFILLELLF WFTFVIGILFIFIKLYNSIMASLPV*" gene complement(3102020..3102577) /gene="yufK" /locus_tag="BSU_31510" /old_locus_tag="BSU31510" misc_feature 3102041..3102060 /Source="Nicolas_upshift_promotors" /id="U2458" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.845154845154845" /psig="0.878121878121878" /xcortree=2785 /SigmaFactorBS="tctgaccaccaaacgctgaaatggctagcttacacaggtaag ctagccatTATGCTATTATAAAGCTTGAtaaatatgaacagaataccgataacaaagg t" /listShort="S1207" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 3102051 /Source="Nicolas_upshifts" /id="U2458" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.845154845154845" /psig="0.878121878121878" /xcortree=2785 /SigmaFactorBS="tctgaccaccaaacgctgaaatggctagcttacacaggtaag ctagccatTATGCTATTATAAAGCTTGAtaaatatgaacagaataccgataacaaagg t" /listShort="S1207" /GFF_Attribute="listLong" downshifts complement(3102061) /Source="Nicolas_upshifts" /id="D1634" /incds=0 /nref=10 /ntot=201 /MaxReadThrough="3.90201" /MaxDrop="3.94501" /score="-6.00543052" /energy="-18.5" /TU="U2459" /idTUdmin="U2459" /TUdmin="-132" /isTUend="FALSE" S_feature 3102073..3102754 /Source="Nicolas_S_feature" /locus_tag="new_3236475_3237156" /HighExp="Diami, Cold, LBGstat, H2O2, Lbtran, Gly, M0t90, GM 10, GM-0.2, dia15" /AntisenseName="yufK" /AntisenseCor="0.32488342936044701" /AntisenseRegPval="-7.3" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.878" /TUlongSig="NA" /TUlongPSig="NA" /label="S1207" promotor_-10 complement(3102603..3102622) /Source="Nicolas_upshift_promotors" /id="U2459" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.846153846153846" /psig=1 /xcortree=2604 /SigmaFactorBS="gtaaaaaggagaaaaaatggaataatttaTCTTGtcaatgtg ttttaagTCCTCCATAATAAATGAGGTagattatagaaagggacttttttatatgaaa a" /listShort="yufK" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3102611) /Source="Nicolas_upshifts" /id="U2459" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.846153846153846" /psig=1 /xcortree=2604 /SigmaFactorBS="gtaaaaaggagaaaaaatggaataatttaTCTTGtcaatgtg ttttaagTCCTCCATAATAAATGAGGTagattatagaaagggacttttttatatgaaa a" /listShort="yufK" /GFF_Attribute="listLong" promotor_-35 complement(3102638..3102642) /Source="Nicolas_upshift_promotors" /id="U2459" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.846153846153846" /psig=1 /xcortree=2604 /SigmaFactorBS="gtaaaaaggagaaaaaatggaataatttaTCTTGtcaatgtg ttttaagTCCTCCATAATAAATGAGGTagattatagaaagggacttttttatatgaaa a" /listShort="yufK" /GFF_Attribute="listLong" /label="promotor_-35" CDS 3102755..3104356 /gene="maeL" /locus_tag="BSU_31520" /old_locus_tag="BSU31520" /EC_number="2.7.13.3" /function="16.12: Sense" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:11717295, 12949159, 12949160, 22001508" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11717295, 12949159, 12949160, 22001508; Product type rc: receptor" /codon_start=1 /transl_table=11 /product="two-component sensor histidine kinase [MaeM]" /protein_id="NP_391030.1" /db_xref="EnsemblGenomes-Gn:BSU31520" /db_xref="EnsemblGenomes-Tr:CAB15141" /db_xref="GOA:O05250" /db_xref="InterPro:IPR000014" /db_xref="InterPro:IPR003594" /db_xref="InterPro:IPR004358" /db_xref="InterPro:IPR005467" /db_xref="InterPro:IPR013767" /db_xref="InterPro:IPR016120" /db_xref="InterPro:IPR029151" /db_xref="InterPro:IPR033463" /db_xref="InterPro:IPR036890" /db_xref="SubtiList:BG12347" /db_xref="UniProtKB/Swiss-Prot:O05250" /translation="MKKTLKLQTRLTIFVCIVVLIALLITFFTVGAQTTKRIRDQEKA TALQTAEMVAEAPMTAAALESGKKQKELQSYTKRVQKITGTEFVVVMDMNGIRKTHPD PSKIGKKFRGGDESEVLKGHVHISTASGTLGKSQRAFVPVYAENGKQVGAVAVGITVN EIDEVISHSLRPLYFIICVSIFVGVIGAVIVARTVKNIMYGLEPYEIATLLEERSAML ESTKEGILAVDEHGKIKLANAEAKRLFVKMGINTNPIDQDVDDILPKSRLKKVIETKK PLQDRDVRINGLELVFNEVPIQLKGQTVGAIATFRDKTEVKHLAEQLSGVKMYANALR AQSHEFMNKLHVILGLVQLKEYDDLGDYIKDIAIQQKSETSEIINDVKSSVLAGFLLG KQSFIREQGANLDIECNGVIPNAADPSVIHELITIIGNLINNGLDAVADMPKKQITMS MRFHNSILDIEITDTGAGMSEEDQAKVFEQGYSTKGKNRGFGLYFTQQSIENLKGQMI LTSEKNEGTTFSIRIPYEPKEENHD*" gene 3102755..3104356 /gene="maeL" /locus_tag="BSU_31520" /old_locus_tag="BSU31520" CDS 3104349..3105056 /gene="maeM" /locus_tag="BSU_31530" /old_locus_tag="BSU31530" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:11717295, 12949159, 12949160, 22001508" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11717295, 12949159, 12949160, 22001508; Product type r: regulator" /codon_start=1 /transl_table=11 /product="two-component response regulator for malate metabolism [MaeL]" /protein_id="NP_391031.1" /db_xref="EnsemblGenomes-Gn:BSU31530" /db_xref="EnsemblGenomes-Tr:CAB15142" /db_xref="GOA:O05251" /db_xref="InterPro:IPR001789" /db_xref="InterPro:IPR011006" /db_xref="InterPro:IPR024187" /db_xref="InterPro:IPR036388" /db_xref="SubtiList:BG12348" /db_xref="UniProtKB/Swiss-Prot:O05251" /translation="MINVLIVEDDPMVGELNKRYLSQIDGFQLKGIASSFQSALHILG EHHIDLILLDIYMPGKNGLELLTELRAQNEAVDVIVISAASELDVIKKTLRYGAVDYL IKPFEFERFQTALSDYRRKQKVYSTHRNMSQKELDAELFQKKEATEKVQLPKGLTKST LKLIWSSIQSFENESFTTEDLAKHTEISQVSIRKYLKFLEDIQVLNVEMAYGTIGRPV FQYNVNNSNINGIKQYL*" gene 3104349..3105056 /gene="maeM" /locus_tag="BSU_31530" /old_locus_tag="BSU31530" downshifts 3105041 /Source="Nicolas_upshifts" /id="D1635" /incds=0 /nref=173 /ntot=245 /MaxReadThrough="1.97489" /MaxDrop="5.86018" /score="19.9464971" /energy="-15.3" /TU="NA" /idTUdmin="U2458" /TUdmin=2660 /isTUend="FALSE" promotor_-35 3105220..3105227 /Source="Nicolas_upshift_promotors" /id="U2460" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.936063936063936" /psig="0.999000999001" /xcortree=2875 /SigmaFactorBS="aattctaaaaatagataatttttaaaaaattatgcgaaattc TATTTATTtcttattagttaaaTGATAAATTATGATTGGTTAgttgatcccgaaaaac t" /listShort="S1208, yufN, yufO, yufP, yufQ, S1209, maeN" /GFF_Attribute="listLong" /label="promotor_-35" S_feature 3105238..3105527 /Source="Nicolas_S_feature" /locus_tag="new_3239640_3239929" /HighExp="T1.30H, T1.0H, T2.30H, T2.0H, M9-stat, S1, T3.0H, T3.30H, T0.30H, S2" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S1208" upshifts 3105238 /Source="Nicolas_upshifts" /id="U2460" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.936063936063936" /psig="0.999000999001" /xcortree=2875 /SigmaFactorBS="aattctaaaaatagataatttttaaaaaattatgcgaaattc TATTTATTtcttattagttaaaTGATAAATTATGATTGGTTAgttgatcccgaaaaac t" /listShort="S1208, yufN, yufO, yufP, yufQ, S1209, maeN" /GFF_Attribute="listLong" promotor_-10 3105242..3105261 /Source="Nicolas_upshift_promotors" /id="U2460" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.936063936063936" /psig="0.999000999001" /xcortree=2875 /SigmaFactorBS="aattctaaaaatagataatttttaaaaaattatgcgaaattc TATTTATTtcttattagttaaaTGATAAATTATGATTGGTTAgttgatcccgaaaaac t" /listShort="S1208, yufN, yufO, yufP, yufQ, S1209, maeN" /GFF_Attribute="listLong" /label="promotor_-10" CDS 3105528..3106607 /gene="nupN" /locus_tag="BSU_31540" /old_locus_tag="BSU31540" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:21926227, 22720735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 21926227, 22720735; Product type lp: lipoprotein" /codon_start=1 /transl_table=11 /product="lipoprotein involved in guanosine transport" /protein_id="NP_391032.2" /db_xref="EnsemblGenomes-Gn:BSU31540" /db_xref="EnsemblGenomes-Tr:CAB15143" /db_xref="GOA:O05252" /db_xref="InterPro:IPR003760" /db_xref="InterPro:IPR028082" /db_xref="SubtiList:BG12349" /db_xref="UniProtKB/Swiss-Prot:O05252" /translation="MNKRKIGLAMSLVIAAGTILGACGNSEKSSGSGEGKNKFSVAMV TDVGGVDDKSFNQSAWEGIQAFGKENGLKKGKNGYDYLQSKSDADYTTNLNKLARENF DLIYGVGYLMEDSISEIADQRKNTNFAIIDAVVDKDNVASITFKEQEGSFLVGVAAAL SSKSGKIGFVGGMESELIKKFEVGFRAGVQAVNPKAVVEVKYAGGFDKADVGKATAES MYKSGVDVIYHSAGATGTGVFTEAKNLKKEDPKRDVWVIGVDKDQYAEGQVEGTDDNV TLTSMVKKVDTVVEDVTKKASDGKFPGGETLTYGLDQDGVGISPSKQNLSDDVIKAVD KWKKKIIDGLEIPATEKELKTFKAE*" gene 3105528..3106607 /gene="nupN" /locus_tag="BSU_31540" /old_locus_tag="BSU31540" CDS 3106683..3108215 /gene="nupO" /locus_tag="BSU_31550" /old_locus_tag="BSU31550" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:21926227, 25875741" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 21926227, 25875741; Product type t: transporter" /codon_start=1 /transl_table=11 /product="guanosine ABC transporter (ATP-binding protein)" /protein_id="NP_391033.1" /db_xref="EnsemblGenomes-Gn:BSU31550" /db_xref="EnsemblGenomes-Tr:CAB15144" /db_xref="GOA:O05253" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR017871" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG12350" /db_xref="UniProtKB/Swiss-Prot:O05253" /translation="MEYVIEMLNIRKAFPGIVANDNINLQVKKGEIHALLGENGAGKS TLMNVLFGLYQPERGEIRVRGEKVHINSPNKANDLGIGMVHQHFMLVDTFTVAENIIL GKEPKKFGRIDRKRAGQEVQDISDRYGLQIHPEAKAADISVGMQQRAEILKTLYRGAD ILIFDEPTAVLTPHEIKELMQIMKNLVKEGKSIILITHKLKEIMEICDRVTVIRKGKG IKTLDVRDTNQDELASLMVGREVSFKTEKRAAQPGAEVLAIDGITVKDTRGIETVRDL SLSVKAGEIVGIAGVDGNGQSELIEAVTGLRKTDSGTITLNGKQIQNLTPRKITESGI GHIPQDRHKHGLVLDFPIGENILLQSYYKKPYSALGVLHKGEMYKKARSLITEYDVRT PDEYTHARALSGGNQQKAIIGREIDRNPDLLIAAQPTRGLDVGAIEFVHKKLIEQRDA GKAVLLLSFELEEIMNLSDRIAVIFEGRIIASVNPQETTEQELGLLMAGSTQKEAGKA NG*" gene 3106683..3108215 /gene="nupO" /locus_tag="BSU_31550" /old_locus_tag="BSU31550" CDS 3108208..3109254 /gene="nupP" /locus_tag="BSU_31560" /old_locus_tag="BSU31560" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:15849754, 16850406, 21926227" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15849754, 16850406, 21926227; Product type t: transporter" /codon_start=1 /transl_table=11 /product="permease of ABC guanosine transporter" /protein_id="NP_391034.1" /db_xref="EnsemblGenomes-Gn:BSU31560" /db_xref="EnsemblGenomes-Tr:CAB15145" /db_xref="GOA:O05254" /db_xref="InterPro:IPR001851" /db_xref="InterPro:IPR002229" /db_xref="InterPro:IPR035568" /db_xref="SubtiList:BG12351" /db_xref="UniProtKB/Swiss-Prot:O05254" /translation="MVKRLSHLLVPLIAIILGLAAGALIMLVSGYSVASGYSALWNGI FGEIYYVGETIRQITPYILSGLAVAFAFRTGLFNIGVEGQLLVGWTAAVWVGTAFDGP AYIHLPLALITAAAAGGLWGFIPGILKARFYVHEVIVTIMMNYIALHMTNYIISNVLT DHQDKTGKIHESASLRSPFLEQITDYSRLHLGIIVALLAAVIMWFIINKSTKGFELRA VGFNQHASQYAGMSVRKNIMTSMLISGAFAGLAGAMEGLGTFEYAAVKGAFTGVGFDG IAVALLGGNTAVGVVLAACLLGGLKIGALNMPIESGVPSEVVDIVIAIIILFVASSYA IRFVMGKLKKKGAN*" gene 3108208..3109254 /gene="nupP" /locus_tag="BSU_31560" /old_locus_tag="BSU31560" CDS 3109255..3110214 /gene="nupQ" /locus_tag="BSU_31570" /old_locus_tag="BSU31570" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:15849754, 16850406, 21926227" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15849754, 16850406, 21926227; Product type t: transporter" /codon_start=1 /transl_table=11 /product="permease of ABC guanosine transporter" /protein_id="NP_391035.1" /db_xref="EnsemblGenomes-Gn:BSU31570" /db_xref="EnsemblGenomes-Tr:CAB15146" /db_xref="GOA:O05255" /db_xref="InterPro:IPR001851" /db_xref="InterPro:IPR035568" /db_xref="SubtiList:BG12352" /db_xref="UniProtKB/Swiss-Prot:O05255" /translation="MDIVQILSIIVPATLVYAAPLILTALGGVFSERSGVVNIGLEGL MIIGAFTSVLFNLFFGQELGAAAPWLSLLAAMAAGALFSLIHAAAAISFRADQTVSGV AINMLALGATLFIVKLIYGKAQTDKIPEPFYKTKIPGLGDIPVLGKIFFSDVYYTSIL AIALAFISWFILFKTPFGLRIRSVGEHPMAADTMGINVYKMRYIGVMISGLFGGLGGG VYASTIALDFTHSTISGQGFIALAALVFGKWHPIGALGAALFFGFAQSLSIIGSLLPL FKDIPNVYMLMAPYILTILALTGFIGRADAPKANGVPYIKGKR*" gene 3109255..3110214 /gene="nupQ" /locus_tag="BSU_31570" /old_locus_tag="BSU31570" S_feature 3110215..3110336 /Source="Nicolas_S_feature" /locus_tag="new_3244617_3244738" /HighExp="S1, BT, M9-stat, T1.30H, S2, LoTm, T1.0H, T2.30H, T2.0H, T3.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S1209" promotor_-35 3110309..3110312 /Source="Nicolas_upshift_promotors" /id="U2461" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.944055944055944" /psig="0.996003996003996" /xcortree=1755 /SigmaFactorBS="taattgtttattagttttttaacttaaaaaaATATgaagtgt taacgctTTCTTGTAGACTGTAACAAAcaatacatgggggtgtatgacatgggagcaa t" /listShort="maeN" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3110327..3110346 /Source="Nicolas_upshift_promotors" /id="U2461" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.944055944055944" /psig="0.996003996003996" /xcortree=1755 /SigmaFactorBS="taattgtttattagttttttaacttaaaaaaATATgaagtgt taacgctTTCTTGTAGACTGTAACAAAcaatacatgggggtgtatgacatgggagcaa t" /listShort="maeN" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3110338 /Source="Nicolas_upshifts" /id="U2461" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.944055944055944" /psig="0.996003996003996" /xcortree=1755 /SigmaFactorBS="taattgtttattagttttttaacttaaaaaaATATgaagtgt taacgctTTCTTGTAGACTGTAACAAAcaatacatgggggtgtatgacatgggagcaa t" /listShort="maeN" /GFF_Attribute="listLong" CDS 3110368..3111714 /gene="maeN" /locus_tag="BSU_31580" /old_locus_tag="BSU31580" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:11004162, 12949159, 15849754, 16850406, 17183219, 19087206, 19114526, 20011599" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11004162, 12949159, 15849754, 16850406, 17183219, 19087206, 19114526, 20011599; Product type t: transporter" /codon_start=1 /transl_table=11 /product="Na+/malate symporter" /protein_id="NP_391036.1" /db_xref="EnsemblGenomes-Gn:BSU31580" /db_xref="EnsemblGenomes-Tr:CAB15147" /db_xref="GOA:O05256" /db_xref="InterPro:IPR004679" /db_xref="InterPro:IPR018025" /db_xref="SubtiList:BG12353" /db_xref="UniProtKB/Swiss-Prot:O05256" /translation="MGAIPKTGTISPEQKDSQEKNLFQKIWSWEIGVIPLPLYTVLAV IIILAAYYNELPANMLGGFAIIMILGVFLGDIGQRIPILKDIGGPAILSLFVPSFLVF YNVLNSTSLDAVTNLMKTSNFLYFYIACLVVGSILGMNRIVLIQGFIRMFVPLVAGTI AAVAAGILVGFIFGYSAYDSFFFVVVPIIAGGIGEGILPLSIAYSQILGSSADVFVSQ LVPAAIIGNVFAIICAALMKKLGDKRPDLNGNGRLVKSKKANEIFNQKEAEAKIDFKL MGAGVLLACTFFIFGGLLEKFIFIPGAILMIISAAAVKYANILPKKMEEGAYQLYKFI SSSFTWPLMVGLGILFIPLDDVASVISIPFVIICISVVIAMIGSGYFVGKLMNMYPVE SAIVTCCHSGLGGTGDVAILSASGRMGLMPFAQISTRLGGAGTVICATVLLRFFTS*" gene 3110368..3111714 /gene="maeN" /locus_tag="BSU_31580" /old_locus_tag="BSU31580" downshifts 3111697 /Source="Nicolas_upshifts" /id="D1636" /incds=0 /nref=68 /ntot=109 /MaxReadThrough="0.286069999999999" /MaxDrop="6.51197" /score="36.240717" /energy="-12.2" /TU="NA" /idTUdmin="U2461" /TUdmin="-12" /isTUend="TRUE" CDS complement(3111750..3111965) /gene="yufS" /locus_tag="BSU_31590" /old_locus_tag="BSU31590" /function="16.8: Protect" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 16845009; Product type f: factor" /codon_start=1 /transl_table=11 /product="putative bacteriocin" /protein_id="NP_391037.1" /db_xref="EnsemblGenomes-Gn:BSU31590" /db_xref="EnsemblGenomes-Tr:CAB15148" /db_xref="GOA:O05257" /db_xref="SubtiList:BG12354" /db_xref="UniProtKB/Swiss-Prot:O05257" /translation="MKTKVVMCSGLFCSVFAGAFMLNQYDGRSGVAACDEWELYLLEH HLSARMSETESKDLPFGPREYIRIVNK*" gene complement(3111750..3111965) /gene="yufS" /locus_tag="BSU_31590" /old_locus_tag="BSU31590" promotor_-35 3111905..3111911 /Source="Nicolas_upshift_promotors" /id="U2462" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=877 /SigmaFactorBS="ccgccacaccgctgcgcccgtcatattgattcaacaTGAATG CccctgcaaatactGAGCAGAATAAAcctgagcacatcacgacttttgttttcacatg a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3111925..3111936 /Source="Nicolas_upshift_promotors" /id="U2462" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=877 /SigmaFactorBS="ccgccacaccgctgcgcccgtcatattgattcaacaTGAATG CccctgcaaatactGAGCAGAATAAAcctgagcacatcacgacttttgttttcacatg a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3111929 /Source="Nicolas_upshifts" /id="U2462" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=877 /SigmaFactorBS="ccgccacaccgctgcgcccgtcatattgattcaacaTGAATG CccctgcaaatactGAGCAGAATAAAcctgagcacatcacgacttttgttttcacatg a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 complement(3111976..3111994) /Source="Nicolas_upshift_promotors" /id="U2463" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.696303696303696" /psig="0.696303696303696" /xcortree=1197 /SigmaFactorBS="aaataagtctaacaaaaaagaggttattTGTATAtttaaaat caatcctGATCAAGCTGAAGGAAAGGagctggtcatgtgaaaacaaaagtcgtgatgt g" /listShort="yufS" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3111983) /Source="Nicolas_upshifts" /id="U2463" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.696303696303696" /psig="0.696303696303696" /xcortree=1197 /SigmaFactorBS="aaataagtctaacaaaaaagaggttattTGTATAtttaaaat caatcctGATCAAGCTGAAGGAAAGGagctggtcatgtgaaaacaaaagtcgtgatgt g" /listShort="yufS" /GFF_Attribute="listLong" promotor_-35 3112008..3112015 /Source="Nicolas_upshift_promotors" /id="U2464" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.96103896103896" /psig="0.998001998001998" /xcortree=1758 /SigmaFactorBS="ccagctcctttccttcagcttgatcaggattgattttaAATA TACAaataacctctttttTGTTAGACTTATTTTGAGGTcaaaagaactcataaaaatc c" /listShort="S1210, S1211, mrpA, mrpB, mrpC, mrpD, mrpE, mrpF, mrpG" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 complement(3112010..3112015) /Source="Nicolas_upshift_promotors" /id="U2463" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.696303696303696" /psig="0.696303696303696" /xcortree=1197 /SigmaFactorBS="aaataagtctaacaaaaaagaggttattTGTATAtttaaaat caatcctGATCAAGCTGAAGGAAAGGagctggtcatgtgaaaacaaaagtcgtgatgt g" /listShort="yufS" /GFF_Attribute="listLong" /label="promotor_-35" S_feature 3112030..3112125 /Source="Nicolas_S_feature" /locus_tag="new_3246432_3246527" /HighExp="G180, Diami, G150, Oxctl, G135, H2O2, Paraq, MG 60, MG 15, MG 25" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.998" /TUlongSig="NA" /TUlongPSig="NA" /label="S1210" promotor_-10 3112030..3112049 /Source="Nicolas_upshift_promotors" /id="U2464" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.96103896103896" /psig="0.998001998001998" /xcortree=1758 /SigmaFactorBS="ccagctcctttccttcagcttgatcaggattgattttaAATA TACAaataacctctttttTGTTAGACTTATTTTGAGGTcaaaagaactcataaaaatc c" /listShort="S1210, S1211, mrpA, mrpB, mrpC, mrpD, mrpE, mrpF, mrpG" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3112030 /Source="Nicolas_upshifts" /id="U2464" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.96103896103896" /psig="0.998001998001998" /xcortree=1758 /SigmaFactorBS="ccagctcctttccttcagcttgatcaggattgattttaAATA TACAaataacctctttttTGTTAGACTTATTTTGAGGTcaaaagaactcataaaaatc c" /listShort="S1210, S1211, mrpA, mrpB, mrpC, mrpD, mrpE, mrpF, mrpG" /GFF_Attribute="listLong" promotor_-35 3112088..3112092 /Source="Nicolas_upshift_promotors" /id="U2465" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.868131868131868" /psig="0.999000999001" /xcortree=2700 /SigmaFactorBS="atccattacagcagttcgaagCGTGGcagcttgcagaaaagT GCGATATAATTTGGACTAGgtcgtttgaccgtatattttatacatagcgcatttttca a" /listShort="S1211, mrpA, mrpB, mrpC, mrpD, mrpE, mrpF, mrpG" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3112108..3112127 /Source="Nicolas_upshift_promotors" /id="U2465" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.868131868131868" /psig="0.999000999001" /xcortree=2700 /SigmaFactorBS="atccattacagcagttcgaagCGTGGcagcttgcagaaaagT GCGATATAATTTGGACTAGgtcgtttgaccgtatattttatacatagcgcatttttca a" /listShort="S1211, mrpA, mrpB, mrpC, mrpD, mrpE, mrpF, mrpG" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 3112127..3112276 /Source="Nicolas_S_feature" /locus_tag="new_3246529_3246678" /HighExp="G135, G180, Diami, G150, H2O2, Oxctl, LBGexp, Paraq, Salt, Lbexp" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="0.999, 0.998" /TUlongSig="NA" /TUlongPSig="NA" /label="S1211" upshifts 3112127 /Source="Nicolas_upshifts" /id="U2465" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.868131868131868" /psig="0.999000999001" /xcortree=2700 /SigmaFactorBS="atccattacagcagttcgaagCGTGGcagcttgcagaaaagT GCGATATAATTTGGACTAGgtcgtttgaccgtatattttatacatagcgcatttttca a" /listShort="S1211, mrpA, mrpB, mrpC, mrpD, mrpE, mrpF, mrpG" /GFF_Attribute="listLong" CDS 3112196..3114601 /gene="mrpA" /locus_tag="BSU_31600" /old_locus_tag="BSU31600" /function="16.8: Protect" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:11004162, 11356194, 12682299, 15019740, 15849754, 16850406, 17693497, 21236240, 24095649, 24139955, 27391676" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11004162, 11356194, 12682299, 15019740, 15849754, 16850406, 17693497, 21236240, 24095649, 24139955, 27391676; Product type t : transporter" /codon_start=1 /transl_table=11 /product="sodium transporter component of a Na+/H+ antiporter" /protein_id="NP_391038.2" /db_xref="EnsemblGenomes-Gn:BSU31600" /db_xref="EnsemblGenomes-Tr:CAB15149" /db_xref="GOA:Q9K2S2" /db_xref="InterPro:IPR001516" /db_xref="InterPro:IPR001750" /db_xref="InterPro:IPR005663" /db_xref="InterPro:IPR018393" /db_xref="InterPro:IPR025383" /db_xref="SubtiList:BG12355" /db_xref="UniProtKB/Swiss-Prot:Q9K2S2" /translation="MQLLHLAILSPFLFAFIIPFLAKYAKRVHTGWFVLILPVLLFIY FLPMIRMTQSGETLRSVLEWIPSLGINFTVYIDGLGLLFALLITGIGSLVTLYSIFYL SKEKEQLGPFYVYLLMFMGAMLGVVLVDNVMVLYMFWELTSLSSFLLIGYWYKREKSR YGAAKSLLITVSGGLCMLGGFILLYLITDSFSIREMVHQVQLIAGHELFIPAMILILL GAFTKSAQFPFYIWLPDAMEAPTPVSAYLHSATMVKAGIYVIARFSPIFAFSAQWFWI VSLVGLFTMVWGSFHAVKQTDLKSILAFSTVSQLGMIISMLGVSAAALHYGHTEYYTV AAMAAIFHLINHATFKGSLFMAVGIIDHETGTRDIRKLGGLMAIMPITFTISLIGTFS MAGLPPFNGFLSKEMFFTSMLRVTHFDLFNVQTWGVLFPLFAWIGSVFTFIYSMKLLF KTFRGNYQPEQLEKQAHEAPVGMLVPPVILVALAVSLFFFPNILSYSLIEPAMNSIYP TLLDGHEKFHVHISQWHGVTTELLMTAGIVVIGTIGYLSLNKWKGIYKLFPSKLTLNR LYDKLLTMMEKGSYRVTKQYMTGFLRDYLLYIFAGFIILIGGAFAIKGGFSFKTEGMA KIGVYEIILTLVMISATVATVFARSRLTAIIALGVVGYTLALFFVIFRAPDLALTQLV IETISVALFLLCFYHLPKLRLKTKTRTFRMTNFIISLGVGVIVTLLGIASSSQRTKDS IASFFVKHSHDLGGGDNVVNVILVDFRGFDTMFEITVLTIAALGIYSMIKTKVKEEGK SGE*" gene 3112196..3114601 /gene="mrpA" /locus_tag="BSU_31600" /old_locus_tag="BSU31600" CDS 3114594..3115025 /gene="mrpB" /locus_tag="BSU_31610" /old_locus_tag="BSU31610" /function="16.1: Circulate" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:11004162, 11356194, 12682299, 15019740, 15849754, 16850406, 17693497, 19389778" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11004162, 11356194, 12682299, 15019740, 15849754, 16850406, 17693497, 19389778; Product type t: transporter" /codon_start=1 /transl_table=11 /product="Na+/H+ antiporter complex" /protein_id="NP_391039.1" /db_xref="EnsemblGenomes-Gn:BSU31610" /db_xref="EnsemblGenomes-Tr:CAB15150" /db_xref="GOA:O05259" /db_xref="InterPro:IPR005281" /db_xref="InterPro:IPR007182" /db_xref="SubtiList:BG12356" /db_xref="UniProtKB/Swiss-Prot:O05259" /translation="MNEQKTNDLILQTATKLVSFIILLFSFYLFLSGHNAPGGGFVGG LITSSSIVLLLLAYDLKTVRSLLPVNFIYVAGAGLLLAVLTGVGSFVFGAPFLTHTFG YFQLPILGKTELATATIFDLGVYLVVVGITMTIIQTIGEEE*" gene 3114594..3115025 /gene="mrpB" /locus_tag="BSU_31610" /old_locus_tag="BSU31610" CDS 3115025..3115366 /gene="mrpC" /locus_tag="BSU_31620" /old_locus_tag="BSU31620" /function="16.1: Circulate" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:11004162, 11356194, 12682299, 15019740, 15849754, 16850406, 17693497, 24021651" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11004162, 11356194, 12682299, 15019740, 15849754, 16850406, 17693497, 24021651; Product type t: transporter" /codon_start=1 /transl_table=11 /product="component of Na+/H+ antiporter" /protein_id="NP_391040.2" /db_xref="EnsemblGenomes-Gn:BSU31620" /db_xref="EnsemblGenomes-Tr:CAB15151" /db_xref="GOA:O05260" /db_xref="SubtiList:BG12357" /db_xref="UniProtKB/Swiss-Prot:O05260" /translation="MEILMAVLAGIIFMAATYLLLSKSLLRVIIGTALLSHGVHLMLL TMGGLKKGAAPILSEHAKSFVDPLPQALILTAIVISFGVTSFILVMAFRAYQELKSDD MDQMRGNDQHE*" gene 3115025..3115366 /gene="mrpC" /locus_tag="BSU_31620" /old_locus_tag="BSU31620" promotor_no_box 3115257..3115357 /Source="Nicolas_upshift_promotors" /id="U2466" /multdbtbs="-" /comp="M10" /sig="Sig-" /pcomp="0.387612387612388" /psig="0.387612387612388" /xcortree=1779 /SigmaFactorBS="tcatttcttttggcgttacgtcattcatcctcgtcatggcct ttcgcgcttatcaggaattgaaatcggacgatatggatcaaatgaggggaaatgatca a" /listShort="mrpD, mrpE, mrpF, mrpG" /GFF_Attribute="listLong" /label="promotor_no_box" upshifts 3115317 /Source="Nicolas_upshifts" /id="U2466" /multdbtbs="-" /comp="M10" /sig="Sig-" /pcomp="0.387612387612388" /psig="0.387612387612388" /xcortree=1779 /SigmaFactorBS="tcatttcttttggcgttacgtcattcatcctcgtcatggcct ttcgcgcttatcaggaattgaaatcggacgatatggatcaaatgaggggaaatgatca a" /listShort="mrpD, mrpE, mrpF, mrpG" /GFF_Attribute="listLong" CDS 3115359..3116840 /gene="mrpD" /locus_tag="BSU_31630" /old_locus_tag="BSU31630" /function="16.8: Protect" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:11004162, 11356194, 12682299, 15019740, 15849754, 16850406, 21236240, 24095649, 27391676" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11004162, 11356194, 12682299, 15019740, 15849754, 16850406, 21236240, 24095649, 27391676; Product type t: transporter" /codon_start=1 /transl_table=11 /product="proton transporter component of Na+/H+ antiporter" /protein_id="NP_391041.3" /db_xref="EnsemblGenomes-Gn:BSU31630" /db_xref="EnsemblGenomes-Tr:CAB15152" /db_xref="GOA:O05229" /db_xref="InterPro:IPR001750" /db_xref="InterPro:IPR003918" /db_xref="InterPro:IPR004775" /db_xref="SubtiList:BG12345" /db_xref="UniProtKB/Swiss-Prot:O05229" /translation="MNNFVILPILIPLLSAILLIFMTKNLMLMRIFSTAASAIGIVIS GILVQTVFTKGIQTLSLGGWKAPYGIVLAADQFASLLVLTTAIIGLLVGLYSFRSVGE KRERSFYYSGVQFLLAGVSGAFLTGDLFNMYVFFELLLIASYMLIVLGGTKIQLRESL KYIVFNIVSSALFVIGVGFLYAVTGTLNMADLSVKISESGQTGLITVIGVLLLLVFGM KGGIFPLYFWLPGSYYAPPAAISALFGALLTKVGLYAITRVFTLIFIHDTAFTHQLMI WLAALTVIFGVIGSLAYSNVMKIVIYNIITAVGVILFGVAVHTPASIQGAIYYLIHDM LIKGALFMLAGTLIALTGTASLHKMGGLIKRYPVLGWMFFISAISLAGIPPLSGFVGK FKIAEGGFAEGEFTISMLILLSSLLVLYSVLRIFIHAFWGEEKETPKPNHRTAKGLLY PAAIFLLLSLLFGLGTEWVSPYVDQAAETLLNPEKYIEAVLKE*" gene 3115359..3116840 /gene="mrpD" /locus_tag="BSU_31630" /old_locus_tag="BSU31630" S_feature complement(3116092..3117960) /Source="Nicolas_S_feature" /locus_tag="new_3250494_3252362_c" /HighExp="S2, Lbstat, T5.0H, T3.30H, S3, T4.0H, T3.0H, T2.30H, S1, T2.0H" /AntisenseName="mrpD" /AntisenseCor="-0.59706140653928796" /AntisenseRegPval="-26.6" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.987" /TUlongSig="NA" /TUlongPSig="NA" /label="S1212" CDS 3116846..3117322 /gene="mrpE" /locus_tag="BSU_31640" /old_locus_tag="BSU31640" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:10198001, 11004162, 15849754, 16233411, 16850406, 24142251" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10198001, 11004162, 15849754, 16233411, 16850406, 24142251; Product type t : transporter" /codon_start=1 /transl_table=11 /product="non essential component of Na+/H+ antiporter" /protein_id="YP_054591.2" /db_xref="EnsemblGenomes-Gn:BSU31640" /db_xref="EnsemblGenomes-Tr:CAE01465" /db_xref="GOA:Q7WY60" /db_xref="InterPro:IPR002758" /db_xref="SubtiList:BG14181" /db_xref="UniProtKB/Swiss-Prot:Q7WY60" /translation="MAFQILLNVFLAFCWMFLSNSPSAAGFITGYILGMLSLFFFRRF FTRQFYLWKLISIIKLCFIFIKELYLANVSVMKSVLSPKLNIRPGIFAFKTELTKDWE ITMLSLLITLTPGTLVMDISDDRTILYIHAMDIEDAEKAIFDIRESFEKAIQEVSR*" gene 3116846..3117322 /gene="mrpE" /locus_tag="BSU_31640" /old_locus_tag="BSU31640" CDS 3117322..3117606 /gene="mrpF" /locus_tag="BSU_31650" /old_locus_tag="BSU31650" /function="16.8: Protect" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:10198001, 11004162, 11356194, 12682299, 15019740, 24142251" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10198001, 11004162, 11356194, 12682299, 15019740, 24142251; Product type t : transporter" /codon_start=1 /transl_table=11 /product="efflux transporter for Na+ and cholate" /protein_id="NP_391043.2" /db_xref="EnsemblGenomes-Gn:BSU31650" /db_xref="EnsemblGenomes-Tr:CAB15153" /db_xref="GOA:O05228" /db_xref="InterPro:IPR007208" /db_xref="SubtiList:BG12344" /db_xref="UniProtKB/Swiss-Prot:O05228" /translation="MFTLILQIALGIMAVSTFLYVIRVIKGPTVPDRVVALDAIGINL IAITALVSILLKTSAFLDIILLLGILSFIGTIAFSKFLEKGEIIENDRNR*" gene 3117322..3117606 /gene="mrpF" /locus_tag="BSU_31650" /old_locus_tag="BSU31650" CDS 3117590..3117964 /gene="mrpG" /locus_tag="BSU_31660" /old_locus_tag="BSU31660" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:11004162, 11356194, 15019740, 15849754, 16850406" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11004162, 11356194, 15019740, 15849754, 16850406; Product type t : transporter" /codon_start=1 /transl_table=11 /product="non essential component of Na+/H+ antiporter" /protein_id="NP_391044.1" /db_xref="EnsemblGenomes-Gn:BSU31660" /db_xref="EnsemblGenomes-Tr:CAB15154" /db_xref="GOA:O05227" /db_xref="InterPro:IPR005133" /db_xref="SubtiList:BG12343" /db_xref="UniProtKB/Swiss-Prot:O05227" /translation="MIETAKVVVAVFILLGALICLIASFGVLRLPDVFTRAHAASKGS TLGVNMILLGVFFYLWFVTGELSAKILLGILFIFITSPIGGHLICRAAYNSGVKLDER SVQDDYNGIRNFVIKRKEDSYL*" gene 3117590..3117964 /gene="mrpG" /locus_tag="BSU_31660" /old_locus_tag="BSU31660" downshifts 3117935 /Source="Nicolas_upshifts" /id="D1637" /incds=0 /nref=86 /ntot=185 /MaxReadThrough="1.46493" /MaxDrop="6.023" /score="32.1865197" /energy="-12.7" /TU="NA" /idTUdmin="U2464" /TUdmin=0 /isTUend="TRUE" CDS complement(3118003..3118383) /gene="yuxO" /locus_tag="BSU_31670" /old_locus_tag="BSU31670" /EC_number="3.1.-.-" /function="18.1: Enzymes of unknown specificity" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 25010423; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative proofreading thioesterase in bacillibactin biosynthesis" /protein_id="NP_391045.2" /db_xref="EnsemblGenomes-Gn:BSU31670" /db_xref="EnsemblGenomes-Tr:CAB15155" /db_xref="GOA:P14205" /db_xref="InterPro:IPR003736" /db_xref="InterPro:IPR006683" /db_xref="InterPro:IPR029069" /db_xref="SubtiList:BG10382" /db_xref="UniProtKB/Swiss-Prot:P14205" /translation="MDMKHTLLEALGIEIVENTAERCVAVMPVDHRTVQPFGYLHGGA SVALAETAASAGAQNLIDHTTQACVGLEINANHLKSVKEGTVKAIAEPVHIGRTTIVY HIHIYDEQERLICISRCTLAVIKK*" gene complement(3118003..3118383) /gene="yuxO" /locus_tag="BSU_31670" /old_locus_tag="BSU31670" downshifts complement(3118005) /Source="Nicolas_upshifts" /id="D1638" /incds=0 /nref=41 /ntot=206 /MaxReadThrough="4.53972" /MaxDrop="3.98532" /score="-4.4938943" /energy="-12.7" /TU="U2469" /idTUdmin="U2469" /TUdmin="-1050" /isTUend="FALSE" CDS complement(3118402..3119046) /gene="comA" /locus_tag="BSU_31680" /old_locus_tag="BSU31680" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:10972833, 11179649, 11717295, 12950917, 16816200, 17827323, 26582911" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10972833, 11179649, 11717295, 12950917, 16816200, 17827323, 26582911; Product type r: regulator" /codon_start=1 /transl_table=11 /product="two-component response quorum-sensing regulator" /protein_id="NP_391046.1" /db_xref="EnsemblGenomes-Gn:BSU31680" /db_xref="EnsemblGenomes-Tr:CAB15156" /db_xref="GOA:P14204" /db_xref="InterPro:IPR000792" /db_xref="InterPro:IPR001789" /db_xref="InterPro:IPR011006" /db_xref="InterPro:IPR016032" /db_xref="InterPro:IPR036388" /db_xref="PDB:2KRF" /db_xref="PDB:3ULQ" /db_xref="SubtiList:BG10381" /db_xref="UniProtKB/Swiss-Prot:P14204" /translation="MKKILVIDDHPAVMEGTKTILETDSNLSVDCLSPEPSEQFIKQH DFSSYDLILMDLNLGGEVNGMELSKQILQENPHCKIIVYTGYEVEDYFEEAIRAGLHG AISKTESKEKITQYIYHVLNGEILVDFAYFKQLMTQQKTKPAPSSQKEQDVLTPRECL ILQEVEKGFTNQEIADALHLSKRSIEYSLTSIFNKLNVGSRTEAVLIAKSDGVL*" gene complement(3118402..3119046) /gene="comA" /locus_tag="BSU_31680" /old_locus_tag="BSU31680" S_feature complement(3119047..3119126) /Source="Nicolas_S_feature" /locus_tag="new_3253449_3253528_c" /HighExp="S2, Lbstat, M0t90, M40t90, MG 5, S1, ferm, T1.30H, nit, S3" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.987" /TUlongSig="NA" /TUlongPSig="NA" /label="S1213" CDS complement(3119127..3121436) /gene="comP" /locus_tag="BSU_31690" /old_locus_tag="BSU31690" /EC_number="2.7.-.-" /function="16.12: Sense" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1c: Function from experimental evidences in the studied genus; PubMedId: 7698645, 7855425, 10419951, 14679219, 15066026, 16091050, 16787201, 20208433, 24130811; Product type rc: receptor" /codon_start=1 /transl_table=11 /product="two-component sensor histidine kinase" /protein_id="NP_391047.2" /db_xref="EnsemblGenomes-Gn:BSU31690" /db_xref="EnsemblGenomes-Tr:CAB15157" /db_xref="GOA:Q99027" /db_xref="InterPro:IPR003594" /db_xref="InterPro:IPR005467" /db_xref="InterPro:IPR011712" /db_xref="InterPro:IPR036890" /db_xref="SubtiList:BG10380" /db_xref="UniProtKB/Swiss-Prot:Q99027" /translation="MKNLIKKFTIAVIVLSILYISYTTYISMNGIIIGTKIHKNDKSQ FMIEEISESSYGQFVGLRQGDIILKINKEKPSDKHLKWGYLSHINSLDILRSGKKIHL KDFDLVTLNRPYSFFLFVLPLFFYFLSIICIFYILKVNKKRRSFAAYILILLLLDISI AYISAGGPFRGHIINRYINLFTFISSPILYLQFIQRYLGEIGKTFLNRISFLYIIPIF NLGIEFFQDYLQVDIDFLATLNLVSFATLTLFSFSAIYLHLNKYKYAEHSFILKLLIL TNTLSFAPFLIFFVLPIIFTGNYIFPALASASLLVLIPFGLVYQFVANKMFDIEFILG RMRYYALLAMIPTLLIVGALVLFDVMDIQMNPVRQTVFFFVVMFAVFYFKEVMDFKFR LKRFSEKFNYQDSIFKYTQLMRGVTSLQQVFKELKNTILDVLLVSKAYTFEVTPDHKV IFLDKHEVGPDWNFYQEEFENVTSEIGKIIEVNQGFLMKVGERGGSSYVLLCLSNINT PRLTRDEISWLKTLSFYTSVSMENVLHIEELMEHLKDLKQEGTNPIWLKKLMFAIEEK QRSGLARDLHDSVLQDLISLKRQCELFLGDFKKDDNPCREEVQDKLVQMNEQMSDVIS MTRETCHELRPQLLYDLGLVKALSKLVAQQQERVPFHIRLNTGRFTASLDLDSQLNLY RIIQEFLSNAVKHSQATDVLIMLISIQNKIVLHYEDDGVGFDQEKNTEHSMSMGLSGI KERVRALDGRLRIETSEGKGFKADIEIEL*" gene complement(3119127..3121436) /gene="comP" /locus_tag="BSU_31690" /old_locus_tag="BSU31690" promotor_-35 3120121..3120128 /Source="Nicolas_upshift_promotors" /id="U2467" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.783216783216783" /psig="0.998001998001998" /xcortree=1977 /SigmaFactorBS="tcaggagtaacctcaaaggtataaGCTTTGCTtacaagcaaa acaTCCAGTATAGTATTTTTCAGttctttaaaaacttgttgaagagaagttacacccc t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3120142..3120161 /Source="Nicolas_upshift_promotors" /id="U2467" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.783216783216783" /psig="0.998001998001998" /xcortree=1977 /SigmaFactorBS="tcaggagtaacctcaaaggtataaGCTTTGCTtacaagcaaa acaTCCAGTATAGTATTTTTCAGttctttaaaaacttgttgaagagaagttacacccc t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3120157 /Source="Nicolas_upshifts" /id="U2467" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.783216783216783" /psig="0.998001998001998" /xcortree=1977 /SigmaFactorBS="tcaggagtaacctcaaaggtataaGCTTTGCTtacaagcaaa acaTCCAGTATAGTATTTTTCAGttctttaaaaacttgttgaagagaagttacacccc t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" S_feature 3121030..3122002 /Source="Nicolas_S_feature" /locus_tag="new_3255432_3256404" /HighExp="S8, C30, S7, Gly, Lbstat, Fru, C90, Pyr, G135, M/G" /AntisenseName="comX" /AntisenseCor="-2.6572990440080099E-2" /AntisenseRegPval="-0.2" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.606" /TUlongSig="NA" /TUlongPSig="NA" /label="S1214" upshifts 3121030 /Source="Nicolas_upshifts" /id="U2468" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.281718281718282" /psig="0.606393606393606" /xcortree=660 /SigmaFactorBS="aataacaatagaataagaatataggcagcaaatgatctcctt tttttatttactttaagtatataaaaaataCATATTATGCTTAAAAAataaaaaaaca a" /listShort="S1214" /GFF_Attribute="listLong" misc_feature 3121042..3121058 /Source="Nicolas_upshift_promotors" /id="U2468" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.281718281718282" /psig="0.606393606393606" /xcortree=660 /SigmaFactorBS="aataacaatagaataagaatataggcagcaaatgatctcctt tttttatttactttaagtatataaaaaataCATATTATGCTTAAAAAataaaaaaaca a" /listShort="S1214" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" CDS complement(3121451..3121618) /gene="comX" /locus_tag="BSU_31700" /old_locus_tag="BSU31700" /function="16.3: Control" /function="16.12: Sense" /experiment="publication(s) with functional evidences, PMID:11751817, 12067344, 14679219, 16407988, 17240141, 18323630, 21636272, 21821957, 28326143, 28391484" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11751817, 12067344, 14679219, 16407988, 17240141, 18323630, 21636272, 21821957, 28326143, 28391484; Product type f: factor" /codon_start=1 /transl_table=11 /product="competence pheromone precursor (pheromone peptide aa 46->55, geranyl-modified)" /protein_id="NP_391048.1" /db_xref="EnsemblGenomes-Gn:BSU31700" /db_xref="EnsemblGenomes-Tr:CAB15158" /db_xref="GOA:P45453" /db_xref="InterPro:IPR009233" /db_xref="SubtiList:BG11324" /db_xref="UniProtKB/Swiss-Prot:P45453" /translation="MQDLINYFLNYPEALKKLKNKEACLIGFDVQETETIIKAYNDYY LADPITRQWGD*" gene complement(3121451..3121618) /gene="comX" /locus_tag="BSU_31700" /old_locus_tag="BSU31700" CDS complement(3121606..3122505) /gene="comQ" /locus_tag="BSU_31710" /old_locus_tag="BSU31710" /function="16.3: Control" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:11751817, 12067344, 14679219, 16407988, 16452308, 17240141, 22878193, 24425772, 25036949" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11751817, 12067344, 14679219, 16407988, 16452308, 17240141, 22878193, 24425772, 25036949; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="isoprenyl transferase (pre-ComX modification)" /protein_id="NP_391049.2" /db_xref="EnsemblGenomes-Gn:BSU31710" /db_xref="EnsemblGenomes-Tr:CAB15159" /db_xref="GOA:P33690" /db_xref="InterPro:IPR000092" /db_xref="InterPro:IPR008949" /db_xref="InterPro:IPR033965" /db_xref="SubtiList:BG10379" /db_xref="UniProtKB/Swiss-Prot:P33690" /translation="MKEIVEQNIFNEDLSQLLYSFIDSKETFSFAESTILHYVVFGGE NLDVATRLGAGIEILILSSDIMDDLEDEDNHHALWMKINRSESLNAALSLYTVGLTSI YSLNNNPLIFKYVLKYVNEAMQGQHDDITNKSKTEDESLEVIRLKCGSLIALANVAGV LLATGEYNETVERYSYYKGIIAQISGDYYVLLSGNRSDIEKNKHTLIYLYLKRLFNDA SEDLLYLISHKDLYYKSLLDKEKFQEKLIKAGVTQYISVLLEIYKQKCISAIEQLNLD KEKKELIKECLLSYTKGDTRCKT*" gene complement(3121606..3122505) /gene="comQ" /locus_tag="BSU_31710" /old_locus_tag="BSU31710" S_feature complement(3122506..3122619) /Source="Nicolas_S_feature" /locus_tag="new_3256908_3257021_c" /HighExp="M9-stat, T1.30H, T0.30H, T1.0H, S4, T2.30H, M0t90, S5, M40t90, S3" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.987" /TUlongSig="NA" /TUlongPSig="NA" /label="S1215" promotor_-10 complement(3122613..3122632) /Source="Nicolas_upshift_promotors" /id="U2469" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.376623376623377" /psig="0.987012987012987" /xcortree=3084 /SigmaFactorBS="gaaacaagtcttttttttcgttctaccGATACAAtaaatgga taaagTATTATATGATTGTTAAAAAacgaaaaacctgctgtcctttaaatgtcccatt t" /listShort="S1215, comQ, comX, comP, S1213, comA, yuxO, S1212" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3122619) /Source="Nicolas_upshifts" /id="U2469" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.376623376623377" /psig="0.987012987012987" /xcortree=3084 /SigmaFactorBS="gaaacaagtcttttttttcgttctaccGATACAAtaaatgga taaagTATTATATGATTGTTAAAAAacgaaaaacctgctgtcctttaaatgtcccatt t" /listShort="S1215, comQ, comX, comP, S1213, comA, yuxO, S1212" /GFF_Attribute="listLong" promotor_-35 complement(3122646..3122652) /Source="Nicolas_upshift_promotors" /id="U2469" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.376623376623377" /psig="0.987012987012987" /xcortree=3084 /SigmaFactorBS="gaaacaagtcttttttttcgttctaccGATACAAtaaatgga taaagTATTATATGATTGTTAAAAAacgaaaaacctgctgtcctttaaatgtcccatt t" /listShort="S1215, comQ, comX, comP, S1213, comA, yuxO, S1212" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3122690..3122830) /gene="degQ" /locus_tag="BSU_31720" /old_locus_tag="BSU31720" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:1901055, 16251307, 16942812, 17827323, 21965392, 26302846, 27920766" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1901055, 16251307, 16942812, 17827323, 21965392, 26302846, 27920766; Product type r: regulator" /codon_start=1 /transl_table=11 /product="pleiotropic regulator" /protein_id="NP_391050.1" /db_xref="EnsemblGenomes-Gn:BSU31720" /db_xref="EnsemblGenomes-Tr:CAB15160" /db_xref="GOA:Q99039" /db_xref="InterPro:IPR012554" /db_xref="SubtiList:BG10378" /db_xref="UniProtKB/Swiss-Prot:Q99039" /translation="MEKKLEEVKQLLFRLELDIKETTDSLRNINKSIDQLDKYNYAMK IS*" gene complement(3122690..3122830) /gene="degQ" /locus_tag="BSU_31720" /old_locus_tag="BSU31720" downshifts complement(3122719) /Source="Nicolas_upshifts" /id="D1639" /incds=0 /nref=2 /ntot=28 /MaxReadThrough="2.48672" /MaxDrop="4.10905" /score="21.4973657" /energy="-6.5" /TU="NA" /idTUdmin="U2470" /TUdmin=0 /isTUend="TRUE" S_feature complement(3122831..3122917) /Source="Nicolas_S_feature" /locus_tag="new_3257233_3257319_c" /HighExp="S2, S4, BC, M9-stat, S5, S3, S6, BT, S8, S7" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.843" /TUlongSig="NA" /TUlongPSig="NA" /label="S1216" promotor_-10 complement(3122901..3122920) /Source="Nicolas_upshift_promotors" /id="U2470" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.38961038961039" /psig="0.843156843156843" /xcortree=464 /SigmaFactorBS="atttgcggtgtcacgcaggacttttttgcatacttttCGGTG AAaaatgagccgaaaGCAGACACACTATTAGTAACagatcaaatacctaggactcgtt c" /listShort="S1216, degQ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3122917) /Source="Nicolas_upshifts" /id="U2470" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.38961038961039" /psig="0.843156843156843" /xcortree=464 /SigmaFactorBS="atttgcggtgtcacgcaggacttttttgcatacttttCGGTG AAaaatgagccgaaaGCAGACACACTATTAGTAACagatcaaatacctaggactcgtt c" /listShort="S1216, degQ" /GFF_Attribute="listLong" promotor_-35 complement(3122934..3122940) /Source="Nicolas_upshift_promotors" /id="U2470" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.38961038961039" /psig="0.843156843156843" /xcortree=464 /SigmaFactorBS="atttgcggtgtcacgcaggacttttttgcatacttttCGGTG AAaaatgagccgaaaGCAGACACACTATTAGTAACagatcaaatacctaggactcgtt c" /listShort="S1216, degQ" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(3123017..3123035) /Source="Nicolas_upshift_promotors" /id="U2471" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.521478521478521" /psig="0.521478521478521" /xcortree=1454 /SigmaFactorBS="atcaaggagattaagaatctttctcaatttcAGCACATataa acgctctttcGCATAGAAAGATAGTCCCGttcttgttgtgattcctttgagtataagg a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3123027) /Source="Nicolas_upshifts" /id="U2471" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.521478521478521" /psig="0.521478521478521" /xcortree=1454 /SigmaFactorBS="atcaaggagattaagaatctttctcaatttcAGCACATataa acgctctttcGCATAGAAAGATAGTCCCGttcttgttgtgattcctttgagtataagg a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(3123050..3123056) /Source="Nicolas_upshift_promotors" /id="U2471" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.521478521478521" /psig="0.521478521478521" /xcortree=1454 /SigmaFactorBS="atcaaggagattaagaatctttctcaatttcAGCACATataa acgctctttcGCATAGAAAGATAGTCCCGttcttgttgtgattcctttgagtataagg a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" CDS 3123052..3123177 /locus_tag="BSU_31725" /old_locus_tag="BSU31725" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_009514001.1" /translation="MLKLRKILNLLDFNGFRIFTKQDYSPSYRIFKIEYAILGVS*" gene 3123052..3123177 /locus_tag="BSU_31725" /old_locus_tag="BSU31725" S_feature complement(3123205..3123634) /Source="Nicolas_S_feature" /locus_tag="new_3257607_3258036_c" /HighExp="LBGtran, G135, C90, Lbtran, Mt0, Lbexp, G150, G180, M40t45, C30" /AntisenseName="yuzC" /AntisenseCor="-0.77553193168722701" /AntisenseRegPval="-54.5" /CDS_PredictionProba="0.143959" /TUshortSig="SigA" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S1217" promotor_-35 3123230..3123235 /Source="Nicolas_upshift_promotors" /id="U2472" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1158 /SigmaFactorBS="aaaagaccgcaacgctaaagttgtggccttttcgctttGTCA TAttcggcaattagggATCTATACATATAGAAACAtccttttttgcgaggtgctccca t" /listShort="yuzC, S1218" /GFF_Attribute="listLong" /label="promotor_-35" downshifts complement(3123247) /Source="Nicolas_upshifts" /id="D1640" /incds=0 /nref=23 /ntot=170 /MaxReadThrough="2.53578" /MaxDrop="3.52021" /score="21.4973657" /energy="-6.5" /TU="NA" /idTUdmin="U2473" /TUdmin=0 /isTUend="TRUE" promotor_-10 3123250..3123268 /Source="Nicolas_upshift_promotors" /id="U2472" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1158 /SigmaFactorBS="aaaagaccgcaacgctaaagttgtggccttttcgctttGTCA TAttcggcaattagggATCTATACATATAGAAACAtccttttttgcgaggtgctccca t" /listShort="yuzC, S1218" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3123252 /Source="Nicolas_upshifts" /id="U2472" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1158 /SigmaFactorBS="aaaagaccgcaacgctaaagttgtggccttttcgctttGTCA TAttcggcaattagggATCTATACATATAGAAACAtccttttttgcgaggtgctccca t" /listShort="yuzC, S1218" /GFF_Attribute="listLong" CDS 3123291..3123659 /gene="cotIC" /locus_tag="BSU_31730" /old_locus_tag="BSU31730" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:16321932" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16321932; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="inner spore coat protein" /protein_id="NP_391051.2" /db_xref="EnsemblGenomes-Gn:BSU31730" /db_xref="EnsemblGenomes-Tr:CAB15161" /db_xref="InterPro:IPR016559" /db_xref="SubtiList:BG14052" /db_xref="UniProtKB/Swiss-Prot:O32089" /translation="MRYRYPWFYVYPYEVRRPPAPANNIDTFIRSAKQAAGIFADAQL VLSRIAGSRELSRRILTAAEQSDKQTIRRLIKQMGVRHEVDTVFNPDGIYISLIGTQS RMILALRWSEDRNHFASIRL*" gene 3123291..3123659 /gene="cotIC" /locus_tag="BSU_31730" /old_locus_tag="BSU31730" CDS complement(3123635..3124864) /gene="pdeH" /locus_tag="BSU_31740" /old_locus_tag="BSU31740" /EC_number="3.1.4.52" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:17153922, 23893111, 28536559" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 17153922, 23893111, 28536559; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="cyclic di-GMP phosphodiesterase" /protein_id="NP_391052.1" /db_xref="EnsemblGenomes-Gn:BSU31740" /db_xref="EnsemblGenomes-Tr:CAB15162" /db_xref="InterPro:IPR001633" /db_xref="InterPro:IPR013976" /db_xref="InterPro:IPR014408" /db_xref="InterPro:IPR035919" /db_xref="SubtiList:BG10377" /db_xref="UniProtKB/Swiss-Prot:P14203" /translation="MRVFVARQPIFNRKEQVVAYELLYRESEENVYSAKDGDQATTDL VINSFLNIGIEKLTEGKRCFVNFTESLMFSNLPTSFNPKQLVIEILEDIPITPALISR CKELKKMGYMLALDDFYAINPQDEDLLEKLMSYIDILKIDFLKTTRMERRTILQTYGC RGLIFLAEKVETRKEYKQAVQDGFQLFQGYFFSEPRIISGHDLSTHFYSYYELLNELS KEQPNIKRVTEYIERDLSLSYQILKFLNSSHSRLSQKIESIQQAIMLLGFNEIKRWIY ILSFKDLSRKGHSSKHEIIKISLIRAKLCELLARKTSRPQPASYMLIGMFSLIDTLLH REIEEIVQELPLKDEVGQALLGHQNDYYQMLELVKLIESNNWDTCSELGNQLDKEEAY ECYLEALEWCHNLMDAK*" gene complement(3123635..3124864) /gene="pdeH" /locus_tag="BSU_31740" /old_locus_tag="BSU31740" S_feature 3123660..3124973 /Source="Nicolas_S_feature" /locus_tag="new_3258062_3259375" /HighExp="S4, S5, S3, S6, LoTm, S8, S7, T5.0H, B36, Pyr" /AntisenseName="yuxH" /AntisenseCor="-0.78363066752642896" /AntisenseRegPval="-56.4" /CDS_PredictionProba="NA" /TUshortSig="SigEF" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S1218" promotor_-10 complement(3124899..3124918) /Source="Nicolas_upshift_promotors" /id="U2473" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.795204795204795" /psig="0.999000999001" /xcortree=2206 /SigmaFactorBS="cgaagggccagttttctttatgtatatattatttttcaTGTT TAGAcaattttcgtcaaaTTATTTGATATACTTAGGGGtgaaagccgcgcgtattgta a" /listShort="yuxH, S1217" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3124918) /Source="Nicolas_upshifts" /id="U2473" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.795204795204795" /psig="0.999000999001" /xcortree=2206 /SigmaFactorBS="cgaagggccagttttctttatgtatatattatttttcaTGTT TAGAcaattttcgtcaaaTTATTTGATATACTTAGGGGtgaaagccgcgcgtattgta a" /listShort="yuxH, S1217" /GFF_Attribute="listLong" downshifts 3124931 /Source="Nicolas_upshifts" /id="D1641" /incds=0 /nref=6 /ntot=30 /MaxReadThrough="1.76106" /MaxDrop="4.58543" /score="22.3133759" /energy="-13.3" /TU="NA" /idTUdmin="U2472" /TUdmin=0 /isTUend="TRUE" promotor_-35 complement(3124933..3124940) /Source="Nicolas_upshift_promotors" /id="U2473" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.795204795204795" /psig="0.999000999001" /xcortree=2206 /SigmaFactorBS="cgaagggccagttttctttatgtatatattatttttcaTGTT TAGAcaattttcgtcaaaTTATTTGATATACTTAGGGGtgaaagccgcgcgtattgta a" /listShort="yuxH, S1217" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3125001..3126473) /gene="pncB" /locus_tag="BSU_31750" /old_locus_tag="BSU31750" /EC_number="6.3.4.21" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 4296374, 12682299, 16199587, 24564896; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="nicotinate phosphoribosyltransferase" /protein_id="NP_391053.1" /db_xref="EnsemblGenomes-Gn:BSU31750" /db_xref="EnsemblGenomes-Tr:CAB15163" /db_xref="GOA:O32090" /db_xref="InterPro:IPR006405" /db_xref="InterPro:IPR007229" /db_xref="InterPro:IPR036068" /db_xref="SubtiList:BG13966" /db_xref="UniProtKB/Swiss-Prot:O32090" /translation="MLEYGFKDDSLSLHTDLYQINMAETYWRDGIHEKKAIFELFFRR LPFENGYAVFAGLEKAIEYLENFKFTDSDLSYLQDELGYHEDFIEYLRGLSFTGSLYS MKEGELVFNNEPIMRVEAPLVEAQLIETALLNIVNYQTLIATKAARIKGVIGDEVALE FGTRRAHEMDAAMWGARAALIGGFSATSNVRAGKRFNIPVSGTHAHALVQAYRDEYTA FKKYAETHKDCVFLVDTYDTLRSGMPNAIRVAKEFGDRINFIGIRLDSGDLAYLSKKA RKMLDEAGFTDAKVIASSDLDEHTIMNLKAQGARIDVWGVGTKLITAYDQPALGAVYK LVAIEEDGKMVDTIKISSNPEKVTTPGRKKVYRIINQSNHHSEGDYIALYDEQVNDQK RLRMFHPVHTFISKFVTNFYAKDLHELIFEKGILCYQNPEISDIQQYVQDNLSLLWEE YKRISKPEEYPVDLSEDCWSNKMQRIHEVKSRIEEELEEE*" gene complement(3125001..3126473) /gene="pncB" /locus_tag="BSU_31750" /old_locus_tag="BSU31750" downshifts complement(3125011) /Source="Nicolas_upshifts" /id="D1642" /incds=0 /nref=200 /ntot=267 /MaxReadThrough="4.08676" /MaxDrop="6.72747" /score="16.2382739" /energy="-14.5" /TU="NA" /idTUdmin="U2475" /TUdmin="-4" /isTUend="TRUE" misc_feature 3126354..3126358 /Source="Nicolas_upshift_promotors" /id="U2474" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.992007992007992" /psig="0.000999000999001" /xcortree=45 /SigmaFactorBS="tccaagcccgcaaatacggcatagccattttcaaacggaagc cttctgaaaaaCAGCTcaaaaatcgctttcttttcatgaatgccgtctctccagtacg t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 3126361 /Source="Nicolas_upshifts" /id="U2474" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.992007992007992" /psig="0.000999000999001" /xcortree=45 /SigmaFactorBS="tccaagcccgcaaatacggcatagccattttcaaacggaagc cttctgaaaaaCAGCTcaaaaatcgctttcttttcatgaatgccgtctctccagtacg t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" downshifts 3126471 /Source="Nicolas_upshifts" /id="D1643" /incds=0 /nref=1 /ntot=123 /MaxReadThrough="1.2059" /MaxDrop="3.08208" /score="22.3133759" /energy="-13.3" /TU="NA" /idTUdmin="U2472" /TUdmin=1540 /isTUend="FALSE" CDS complement(3126489..3127040) /gene="pncA" /locus_tag="BSU_31760" /old_locus_tag="BSU31760" /EC_number="3.5.1.19" /function="16.11: Scavenge (Catabolism)" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 15135535, 17382284, 18616465, 24340054, 24512664; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="nicotinamidase; NAD salvage pathway" /protein_id="NP_391054.1" /db_xref="EnsemblGenomes-Gn:BSU31760" /db_xref="EnsemblGenomes-Tr:CAB15164" /db_xref="GOA:O32091" /db_xref="InterPro:IPR000868" /db_xref="InterPro:IPR036380" /db_xref="SubtiList:BG13965" /db_xref="UniProtKB/Swiss-Prot:O32091" /translation="MKKALICIDYTNDFVASDGKLTCGEPGRMIEEAIVNLTKEFITN GDYVVLAVDSHDEGDQYHPETRLFPPHNIKGTEGKDLYGKLLPLYQKHEHEPNVYYME KTRYSAFAGTDLELKLRERQIGELHLAGVCTDICVLHTAVDAYNKGFRIVVHKQAVAS FNQEGHAWALSHFANSIGAQVAE*" gene complement(3126489..3127040) /gene="pncA" /locus_tag="BSU_31760" /old_locus_tag="BSU31760" promotor_-10 complement(3127062..3127081) /Source="Nicolas_upshift_promotors" /id="U2475" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.668331668331668" /psig=1 /xcortree=2232 /SigmaFactorBS="agacaaacggaccgtttgtctttttgttcatggcAATTCACT tacaactggagaTAAGATATAATGTTCTCATActgatggcggggaggccggctatgaa a" /listShort="pncA, pncB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3127075) /Source="Nicolas_upshifts" /id="U2475" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.668331668331668" /psig=1 /xcortree=2232 /SigmaFactorBS="agacaaacggaccgtttgtctttttgttcatggcAATTCACT tacaactggagaTAAGATATAATGTTCTCATActgatggcggggaggccggctatgaa a" /listShort="pncA, pncB" /GFF_Attribute="listLong" promotor_-35 complement(3127094..3127101) /Source="Nicolas_upshift_promotors" /id="U2475" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.668331668331668" /psig=1 /xcortree=2232 /SigmaFactorBS="agacaaacggaccgtttgtctttttgttcatggcAATTCACT tacaactggagaTAAGATATAATGTTCTCATActgatggcggggaggccggctatgaa a" /listShort="pncA, pncB" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3127137..3127535) /gene="yueI" /locus_tag="BSU_31770" /old_locus_tag="BSU31770" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_391055.1" /db_xref="EnsemblGenomes-Gn:BSU31770" /db_xref="EnsemblGenomes-Tr:CAB15165" /db_xref="InterPro:IPR012543" /db_xref="InterPro:IPR029064" /db_xref="PDB:2OHW" /db_xref="SubtiList:BG13964" /db_xref="UniProtKB/Swiss-Prot:O32092" /translation="MSEDKMDLYLQQGMYGPLETKPDERHLFLGSLRERVVLALTKGQ VLRSKPYKEAEHELKNSHNVTLLINGELQYQSYSSYIQMASRYGVPFKIVSDLQFHTP LGIVIAADIAVNRELIYIQDDIYNRSVLKS*" gene complement(3127137..3127535) /gene="yueI" /locus_tag="BSU_31770" /old_locus_tag="BSU31770" S_feature complement(3127536..3127606) /Source="Nicolas_S_feature" /locus_tag="new_3261938_3262008_c" /HighExp="Etha, dia5, Diami, dia15, H2O2, LBGtran, LPhT, G135, G180, Salt" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="1, 0.999" /TUlongSig="SigA" /TUlongPSig="0.998" /label="S1219" CDS complement(3127607..3127855) /gene="yueH" /locus_tag="BSU_31780" /old_locus_tag="BSU31780" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_391056.1" /db_xref="EnsemblGenomes-Gn:BSU31780" /db_xref="EnsemblGenomes-Tr:CAB15166" /db_xref="InterPro:IPR020260" /db_xref="SubtiList:BG13963" /db_xref="UniProtKB/Swiss-Prot:O32093" /translation="MKIRKANINTQTGMITDVYLHENRKELRTLVAVPQLEWSTIISY EEDKATLPERLEASLRRHTEETPAGELAKKIIHWVTEM*" gene complement(3127607..3127855) /gene="yueH" /locus_tag="BSU_31780" /old_locus_tag="BSU31780" promotor_-10 complement(3127878..3127897) /Source="Nicolas_upshift_promotors" /id="U2476" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.703296703296703" /psig=1 /xcortree=1994 /SigmaFactorBS="aacagtttcgtttaacgggtaacagccttttcaCAAGaggct gttgctttttTATTGTATAATATGGGTAGTctttgaatagagaggtcatgttatgaaa a" /listShort="yueH, S1219, yueI, pncA, pncB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3127889) /Source="Nicolas_upshifts" /id="U2476" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.703296703296703" /psig=1 /xcortree=1994 /SigmaFactorBS="aacagtttcgtttaacgggtaacagccttttcaCAAGaggct gttgctttttTATTGTATAATATGGGTAGTctttgaatagagaggtcatgttatgaaa a" /listShort="yueH, S1219, yueI, pncA, pncB" /GFF_Attribute="listLong" promotor_-35 complement(3127913..3127916) /Source="Nicolas_upshift_promotors" /id="U2476" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.703296703296703" /psig=1 /xcortree=1994 /SigmaFactorBS="aacagtttcgtttaacgggtaacagccttttcaCAAGaggct gttgctttttTATTGTATAATATGGGTAGTctttgaatagagaggtcatgttatgaaa a" /listShort="yueH, S1219, yueI, pncA, pncB" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3127928..3128149) /gene="yueG" /locus_tag="BSU_31790" /old_locus_tag="BSU31790" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type f: factor" /codon_start=1 /transl_table=11 /product="putative spore germination protein" /protein_id="NP_391057.1" /db_xref="EnsemblGenomes-Gn:BSU31790" /db_xref="EnsemblGenomes-Tr:CAB15167" /db_xref="InterPro:IPR019618" /db_xref="SubtiList:BG13962" /db_xref="UniProtKB/Swiss-Prot:O32094" /translation="MPAIVGPIYIMSVTDNAAASFGDVFAISPKSVAHSGAGSGTFQL GDFVKINNQTSKTLFKDADITDETVSFNG*" gene complement(3127928..3128149) /gene="yueG" /locus_tag="BSU_31790" /old_locus_tag="BSU31790" downshifts complement(3127955) /Source="Nicolas_upshifts" /id="D1644" /incds=0 /nref=11 /ntot=31 /MaxReadThrough="3.65047" /MaxDrop="4.3681" /score="19.032155" /energy="-12.6" /TU="U2477,U2479,U2482" /idTUdmin="U2482" /TUdmin="-44" /isTUend="FALSE" downshifts 3128143 /Source="Nicolas_upshifts" /id="D1645" /incds=0 /nref=1 /ntot=3 /MaxReadThrough="1.17049" /MaxDrop="3.0193" /score="-7.47675224" /energy="-6.7" /TU="NA" /idTUdmin="U2480" /TUdmin="-1320" /isTUend="FALSE" promotor_-10 complement(3128167..3128186) /Source="Nicolas_upshift_promotors" /id="U2477" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1310 /SigmaFactorBS="ggaaaacgcaaagccagctgaatagGCGGGCACCAttatcgg ctcctTGCATATGATGCTGTAAATCaatgcggaggtggggaaatgcctgcaattgtgg g" /listShort="yueG, yueH" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3128173) /Source="Nicolas_upshifts" /id="U2477" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1310 /SigmaFactorBS="ggaaaacgcaaagccagctgaatagGCGGGCACCAttatcgg ctcctTGCATATGATGCTGTAAATCaatgcggaggtggggaaatgcctgcaattgtgg g" /listShort="yueG, yueH" /GFF_Attribute="listLong" promotor_-35 complement(3128199..3128208) /Source="Nicolas_upshift_promotors" /id="U2477" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1310 /SigmaFactorBS="ggaaaacgcaaagccagctgaatagGCGGGCACCAttatcgg ctcctTGCATATGATGCTGTAAATCaatgcggaggtggggaaatgcctgcaattgtgg g" /listShort="yueG, yueH" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3128209..3129318) /gene="yueF" /locus_tag="BSU_31800" /old_locus_tag="BSU31800" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 10960106, 15849754, 16850406; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative integral inner membrane protein" /protein_id="NP_391058.1" /db_xref="EnsemblGenomes-Gn:BSU31800" /db_xref="EnsemblGenomes-Tr:CAB15168" /db_xref="GOA:O32095" /db_xref="InterPro:IPR002549" /db_xref="SubtiList:BG13961" /db_xref="UniProtKB/Swiss-Prot:O32095" /translation="MLKSKVHFWTLQILFVLLIIFVATKVSFVFQPFIVFISTLFFPM LIAGILYFIFNPVVRLLEKKIPRTLSILLIYLLFIGLLAFISASVGPIITAQVTGLFN NLPDYIKQIQALTKDLSHSQWFTWMMNQDYVSISKIEQSLTSFLQNLPQNITSSLSAV FGVVTNITLVIITVPFILFYMLKDGHRFPHLAVKILPASYRTEGLKIFKDLSDTLAAY FQGQLLICLFVGTACFIGYLIAGLPYALILGIVMAITNIIPYVGPFLGAAPAVIVGFM DSPAKALFAIIVVVIVQQLDGNLLSPLVIGKRLNTHPLTIILLLIGAGSFGGILGMIL AVPVYAVVKAFFLNIVRLIKLRQRSRLEENAKPAE*" gene complement(3128209..3129318) /gene="yueF" /locus_tag="BSU_31800" /old_locus_tag="BSU31800" promotor_-35 3128970..3128977 /Source="Nicolas_upshift_promotors" /id="U2478" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.984015984015984" /psig=1 /xcortree=2030 /SigmaFactorBS="ccaggtaaaccattgagaatgggacaaatCCTTTGTCagcgc ctgaatctgTTTTATATAATCAGGAAGGTtgttaaacagccctgtcacctgtgcggtg a" /listShort="S1220, yuzE" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3128992..3129011 /Source="Nicolas_upshift_promotors" /id="U2478" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.984015984015984" /psig=1 /xcortree=2030 /SigmaFactorBS="ccaggtaaaccattgagaatgggacaaatCCTTTGTCagcgc ctgaatctgTTTTATATAATCAGGAAGGTtgttaaacagccctgtcacctgtgcggtg a" /listShort="S1220, yuzE" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 3129001..3129395 /Source="Nicolas_S_feature" /locus_tag="new_3263403_3263797" /HighExp="dia15, S8, H2O2, dia5, LBGstat, Paraq, C30, S7, Diami, G180" /AntisenseName="yueF" /AntisenseCor="0.28555063485711402" /AntisenseRegPval="-5.7" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1220" upshifts 3129001 /Source="Nicolas_upshifts" /id="U2478" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.984015984015984" /psig=1 /xcortree=2030 /SigmaFactorBS="ccaggtaaaccattgagaatgggacaaatCCTTTGTCagcgc ctgaatctgTTTTATATAATCAGGAAGGTtgttaaacagccctgtcacctgtgcggtg a" /listShort="S1220, yuzE" /GFF_Attribute="listLong" promotor_-10 complement(3129366..3129385) /Source="Nicolas_upshift_promotors" /id="U2479" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.380619380619381" /psig="0.999000999001" /xcortree=2209 /SigmaFactorBS="cggccttcatcaccaacactcctttcattatattaagaGTTC TGatatgagttcattTTTGTTACAATGATGGGGTAtaagttcttttatctgacagaca a" /listShort="yueF, yueG, yueH, S1219, yueI" /listLong="pncA, pncB" /label="promotor_-10" upshifts complement(3129382) /Source="Nicolas_upshifts" /id="U2479" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.380619380619381" /psig="0.999000999001" /xcortree=2209 /SigmaFactorBS="cggccttcatcaccaacactcctttcattatattaagaGTTC TGatatgagttcattTTTGTTACAATGATGGGGTAtaagttcttttatctgacagaca a" /listShort="yueF, yueG, yueH, S1219, yueI" /listLong="pncA, pncB" S_feature complement(3129384..3129824) /Source="Nicolas_S_feature" /locus_tag="new_3263786_3264226_c" /HighExp="Diami, S8, H2O2, S7, C90, Paraq, Salt, S1, dia15, dia5" /AntisenseName="yuzE" /AntisenseCor="0.47136608606324898" /AntisenseRegPval="-15.6" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.998" /TUlongSig="NA" /TUlongPSig="NA" /label="S1221" promotor_-35 3129387..3129389 /Source="Nicolas_upshift_promotors" /id="U2480" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.657342657342657" /psig="0.657342657342657" /xcortree=1364 /SigmaFactorBS="tttctttgtctgtcagataaaagaacttataccccatcattg taacaaaaATGaactcatatcagaacTCTTAATATAATGAAAGGAGtgttggtgatga a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 3129397 /Source="Nicolas_upshifts" /id="U2480" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.657342657342657" /psig="0.657342657342657" /xcortree=1364 /SigmaFactorBS="tttctttgtctgtcagataaaagaacttataccccatcattg taacaaaaATGaactcatatcagaacTCTTAATATAATGAAAGGAGtgttggtgatga a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(3129399..3129404) /Source="Nicolas_upshift_promotors" /id="U2479" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.380619380619381" /psig="0.999000999001" /xcortree=2209 /SigmaFactorBS="cggccttcatcaccaacactcctttcattatattaagaGTTC TGatatgagttcattTTTGTTACAATGATGGGGTAtaagttcttttatctgacagaca a" /listShort="yueF, yueG, yueH, S1219, yueI" /listLong="pncA, pncB" /label="promotor_-35" promotor_-10 3129405..3129424 /Source="Nicolas_upshift_promotors" /id="U2480" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.657342657342657" /psig="0.657342657342657" /xcortree=1364 /SigmaFactorBS="tttctttgtctgtcagataaaagaacttataccccatcattg taacaaaaATGaactcatatcagaacTCTTAATATAATGAAAGGAGtgttggtgatga a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" CDS 3129433..3129822 /gene="yuzE" /locus_tag="BSU_31810" /old_locus_tag="BSU31810" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_391059.1" /db_xref="EnsemblGenomes-Gn:BSU31810" /db_xref="EnsemblGenomes-Tr:CAB15169" /db_xref="InterPro:IPR016789" /db_xref="InterPro:IPR019270" /db_xref="SubtiList:BG14054" /db_xref="UniProtKB/Swiss-Prot:O32096" /translation="MKAVTYDTDSELAYIYVLPPKKNRNVRTEELRVNDCLLLDISQD GKIAGFECFGEAAHLCAPFAGKSRLYVKDSDGYHFRVCQHASVRSCYTVYRVTFCFSD GDYQEFAGFDLDGTMYHSAFLQRLTEK*" gene 3129433..3129822 /gene="yuzE" /locus_tag="BSU_31810" /old_locus_tag="BSU31810" CDS complement(3129863..3130099) /gene="yuzF" /locus_tag="BSU_31820" /old_locus_tag="BSU31820" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_391060.1" /db_xref="EnsemblGenomes-Gn:BSU31820" /db_xref="EnsemblGenomes-Tr:CAB15170" /db_xref="InterPro:IPR020139" /db_xref="SubtiList:BG14055" /db_xref="UniProtKB/Swiss-Prot:O32097" /translation="MVNQGSPQLVSLVDPYVYQTIKKLIGSRFVIQTVRDTVRGRLID VKPDHITIEGARNSVCLIRIQHMISVTPDYSERV*" gene complement(3129863..3130099) /gene="yuzF" /locus_tag="BSU_31820" /old_locus_tag="BSU31820" downshifts complement(3129869) /Source="Nicolas_upshifts" /id="D1646" /incds=0 /nref=12 /ntot=37 /MaxReadThrough="5.19136" /MaxDrop="5.1675" /score="30.7642328" /energy="-9.9" /TU="U2482" /idTUdmin="U2481" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(3130119..3130138) /Source="Nicolas_upshift_promotors" /id="U2481" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=1324 /SigmaFactorBS="aatctccgcacccctttgttttatcaggtaagCCTGTGTCAT tatccataagcgcGGCATAAGCTGAGATAAAACacacaaaggggataaaagtatggtc a" /listShort="yuzF" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3130133) /Source="Nicolas_upshifts" /id="U2481" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=1324 /SigmaFactorBS="aatctccgcacccctttgttttatcaggtaagCCTGTGTCAT tatccataagcgcGGCATAAGCTGAGATAAAACacacaaaggggataaaagtatggtc a" /listShort="yuzF" /GFF_Attribute="listLong" S_feature complement(3130135..3130275) /Source="Nicolas_S_feature" /locus_tag="new_3264537_3264677_c" /HighExp="BT, Diami, S8, Etha, Sw, C90, Salt, B36, LPhT, S6" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigK" /TUshortPSig="0.998, 0.989" /TUlongSig="NA" /TUlongPSig="NA" /label="S1222" promotor_-35 complement(3130152..3130161) /Source="Nicolas_upshift_promotors" /id="U2481" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=1324 /SigmaFactorBS="aatctccgcacccctttgttttatcaggtaagCCTGTGTCAT tatccataagcgcGGCATAAGCTGAGATAAAACacacaaaggggataaaagtatggtc a" /listShort="yuzF" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3130276..3130806) /gene="yueE" /locus_tag="BSU_31830" /old_locus_tag="BSU31830" /EC_number="3.-.-.-" /function="16.6: Maintain" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative metal-dependent phosphohydrolase" /protein_id="NP_391061.1" /db_xref="EnsemblGenomes-Gn:BSU31830" /db_xref="EnsemblGenomes-Tr:CAB15171" /db_xref="GOA:O32098" /db_xref="InterPro:IPR003607" /db_xref="InterPro:IPR006674" /db_xref="InterPro:IPR006675" /db_xref="SubtiList:BG13960" /db_xref="UniProtKB/Swiss-Prot:O32098" /translation="MRKVTLMDVFTHPIAQKYLQRSGVAHAIACAYHAYRLSVKADIN PDLAAKAALLHDIGHYEWYTDGKWDYEKYKRNDIHAIKGAERAHKLLIRLGEEPKAAK EIALAILLHTDSYLPEGELDKNTLQQIVKKADELDEEPGGHHHYRQIDPSTARKKIEK LDQLIDQAQASVIKPV*" gene complement(3130276..3130806) /gene="yueE" /locus_tag="BSU_31830" /old_locus_tag="BSU31830" promotor_-10 complement(3130826..3130845) /Source="Nicolas_upshift_promotors" /id="U2482" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.494505494505495" /psig="0.998001998001998" /xcortree=636 /SigmaFactorBS="atgataagaagatcaaaatgatgtgacataagAATTGAGTTt ctctgcaaatTATGTTAGGATTCTAAAAATatctaaaggaggggtttccatgagaaag g" /listShort="yueE, S1222, yuzF, S1221, yueF, yueG" /listLong="yueH, S1219, yueI, pncA, pncB" /label="promotor_-10" upshifts complement(3130837) /Source="Nicolas_upshifts" /id="U2482" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.494505494505495" /psig="0.998001998001998" /xcortree=636 /SigmaFactorBS="atgataagaagatcaaaatgatgtgacataagAATTGAGTTt ctctgcaaatTATGTTAGGATTCTAAAAATatctaaaggaggggtttccatgagaaag g" /listShort="yueE, S1222, yuzF, S1221, yueF, yueG" /listLong="yueH, S1219, yueI, pncA, pncB" S_feature complement(3130839..3130925) /Source="Nicolas_S_feature" /locus_tag="new_3265241_3265327_c" /HighExp="BT, S8, S6, S7, B36, Etha, S5, S4, Pyr, B60" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigK" /TUshortPSig="0.989" /TUlongSig="NA" /TUlongPSig="NA" /label="S1223" promotor_-35 complement(3130857..3130865) /Source="Nicolas_upshift_promotors" /id="U2482" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.494505494505495" /psig="0.998001998001998" /xcortree=636 /SigmaFactorBS="atgataagaagatcaaaatgatgtgacataagAATTGAGTTt ctctgcaaatTATGTTAGGATTCTAAAAATatctaaaggaggggtttccatgagaaag g" /listShort="yueE, S1222, yuzF, S1221, yueF, yueG" /listLong="yueH, S1219, yueI, pncA, pncB" /label="promotor_-35" promotor_-10 complement(3130920..3130939) /Source="Nicolas_upshift_promotors" /id="U2483" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.98901098901099" /psig="0.98901098901099" /xcortree=730 /SigmaFactorBS="tcttttttttatacaaaaggctgcaGCCAGCGCATtttattg aacagcCGCATATACTGACTGAAACGttgcttttagggtataacaatgatgataagaa g" /listShort="S1223, yueE, S1222, yuzF" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3130927) /Source="Nicolas_upshifts" /id="U2483" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.98901098901099" /psig="0.98901098901099" /xcortree=730 /SigmaFactorBS="tcttttttttatacaaaaggctgcaGCCAGCGCATtttattg aacagcCGCATATACTGACTGAAACGttgcttttagggtataacaatgatgataagaa g" /listShort="S1223, yueE, S1222, yuzF" /GFF_Attribute="listLong" promotor_-35 complement(3130953..3130962) /Source="Nicolas_upshift_promotors" /id="U2483" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.98901098901099" /psig="0.98901098901099" /xcortree=730 /SigmaFactorBS="tcttttttttatacaaaaggctgcaGCCAGCGCATtttattg aacagcCGCATATACTGACTGAAACGttgcttttagggtataacaatgatgataagaa g" /listShort="S1223, yueE, S1222, yuzF" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3131004..3131735) /gene="bznD" /locus_tag="BSU_31840" /old_locus_tag="BSU31840" /EC_number="1.1.1.320" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1c: Function from experimental evidences in the studied genus; PubMedId: 11745140, 21670841; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="benzil reductase (benzoin forming)" /protein_id="NP_391062.1" /db_xref="EnsemblGenomes-Gn:BSU31840" /db_xref="EnsemblGenomes-Tr:CAB15172" /db_xref="GOA:O32099" /db_xref="InterPro:IPR002347" /db_xref="InterPro:IPR020904" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG13959" /db_xref="UniProtKB/Swiss-Prot:O32099" /translation="MELYIITGASKGLGQAIALQALEKGHEVHALSRTKTDVSHKKLT QHQIDLINLEEAEQQFETLLSSIDSDRYSGITLINNAGMVTPIKRAGEASLDELQRHY QLNLTAPVLLSQLFTKRFASYSGKKTVVNITSGAAKNPYKGWSAYCSSKAGLDMFTRT FGFEQEDEELPVNMISFSPGVMDTEMQAVIRSSSKKDFHHIERFRKLNETGSLRSPDF IAGTLLSLLEKGTENGRIYDIKEFL*" gene complement(3131004..3131735) /gene="bznD" /locus_tag="BSU_31840" /old_locus_tag="BSU31840" downshifts complement(3131034) /Source="Nicolas_upshifts" /id="D1647" /incds=0 /nref=183 /ntot=253 /MaxReadThrough="2.76356" /MaxDrop="5.18507" /score="30.7642328" /energy="-9.9" /TU="NA" /idTUdmin="U2484" /TUdmin="-21" /isTUend="TRUE" promotor_-10 complement(3131750..3131769) /Source="Nicolas_upshift_promotors" /id="U2484" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.996003996003996" /psig=1 /xcortree=2058 /SigmaFactorBS="gcgcaggaaaacaagaaggcgtaggccgcgTGCTTGTGttgt gtaaaagaggTGCCGTACAATAATAACGGAaaaggaggtttccaatggaactttatat c" /listShort="yueD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3131761) /Source="Nicolas_upshifts" /id="U2484" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.996003996003996" /psig=1 /xcortree=2058 /SigmaFactorBS="gcgcaggaaaacaagaaggcgtaggccgcgTGCTTGTGttgt gtaaaagaggTGCCGTACAATAATAACGGAaaaggaggtttccaatggaactttatat c" /listShort="yueD" /GFF_Attribute="listLong" promotor_-35 complement(3131784..3131791) /Source="Nicolas_upshift_promotors" /id="U2484" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.996003996003996" /psig=1 /xcortree=2058 /SigmaFactorBS="gcgcaggaaaacaagaaggcgtaggccgcgTGCTTGTGttgt gtaaaagaggTGCCGTACAATAATAACGGAaaaggaggtttccaatggaactttatat c" /listShort="yueD" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3131798..3132253) /gene="yueC" /locus_tag="BSU_31850" /old_locus_tag="BSU31850" /function="11.1: Protein and peptide secretion and trafficking" /experiment="publication(s) with functional evidences, PMID:15576783, 24798022" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15576783, 24798022; Product type t: transporter" /codon_start=1 /transl_table=11 /product="ESX secretion system YueC protein" /protein_id="NP_391063.1" /db_xref="EnsemblGenomes-Gn:BSU31850" /db_xref="EnsemblGenomes-Tr:CAB15173" /db_xref="GOA:O32100" /db_xref="InterPro:IPR018920" /db_xref="InterPro:IPR020212" /db_xref="SubtiList:BG13958" /db_xref="UniProtKB/Swiss-Prot:O32100" /translation="MLSFSLFIPSAAAAQTEENTDVAPNQYEKKDIEIDTNYLHEDTY YEEKTELPEEQKDITFDKPKDKDAELIKDLFTSTNAEDSNTIAAQSKQLGITFAEKPM TKTSSTETEDEQETSSLLLPMIYVVLILLGIAGIVFLIPKVTAQENKKA*" gene complement(3131798..3132253) /gene="yueC" /locus_tag="BSU_31850" /old_locus_tag="BSU31850" promotor_-35 3132206..3132212 /Source="Nicolas_upshift_promotors" /id="U2485" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=235 /SigmaFactorBS="actggtttggcgcgacatctgtattttcttcAGTTTGGgcag ccgctgcagaGGGTATGAAAAGGGAAAAGgagagcatacaaatcatgatccccttttc c" /listShort="S1224" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3132227..3132245 /Source="Nicolas_upshift_promotors" /id="U2485" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=235 /SigmaFactorBS="actggtttggcgcgacatctgtattttcttcAGTTTGGgcag ccgctgcagaGGGTATGAAAAGGGAAAAGgagagcatacaaatcatgatccccttttc c" /listShort="S1224" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 3132235..3134602 /Source="Nicolas_S_feature" /locus_tag="new_3266637_3269004" /HighExp="Etha, Gly, Sw, Salt, LoTm, C30, BT, HiTm, Mal, G135" /AntisenseName="yueB" /AntisenseCor="-9.3455707286730305E-2" /AntisenseRegPval="-0.9" /CDS_PredictionProba="NA" /TUshortSig="SigB" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1224" upshifts 3132235 /Source="Nicolas_upshifts" /id="U2485" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=235 /SigmaFactorBS="actggtttggcgcgacatctgtattttcttcAGTTTGGgcag ccgctgcagaGGGTATGAAAAGGGAAAAGgagagcatacaaatcatgatccccttttc c" /listShort="S1224" /GFF_Attribute="listLong" CDS complement(3132285..3135515) /gene="yueB" /locus_tag="BSU_31860" /old_locus_tag="BSU31860" /function="11.1: Protein and peptide secretion and trafficking" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:15576783, 24798022, 27179995" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15576783, 24798022, 27179995; Product type t: transporter" /codon_start=1 /transl_table=11 /product="ESX secretion system; calcium-dependent phage SPP1 attachment site" /protein_id="NP_391064.1" /db_xref="EnsemblGenomes-Gn:BSU31860" /db_xref="EnsemblGenomes-Tr:CAB15174" /db_xref="GOA:O32101" /db_xref="InterPro:IPR023838" /db_xref="SubtiList:BG13957" /db_xref="UniProtKB/Swiss-Prot:O32101" /translation="MTEQRKSLIKLISAVIIILLLPVLFFRFIGDDPTKKAVNSTRQI AVVNEDTGVLSDEVKSDEEDKSAQFGKEVAAVLGERPDYSWTVVNRSAAETGLASKKY DAIVYIPSDFSKNILSYDKDHPQKATLEFSIQDNLNAVNKEKVQRELEDAQKTMNKKM SALYWNFVSQKVDNIRGEFDKIVNKESEFQNVMYNFYKPSSNDLAGEIKQQKDLIDEL KKSMNEAQGTTKEKASTAEEAKNTLKEFIDTVERYKEYQENQKKLLLAAQDSTQQQIR TGLDAIQAQQKANQFSERMSGLATGIGQAKTQIGLTNLALNNAEKLRQNQVPLQEMGM KKIENDMFNAFLSRYKSQYEAIKYQNLNQLQENIGKNRLSLLKPKESDEKEDGEDTSD NKDDTDKEDIEDIKLDLEKQRDELKNVATEIKDISEGLKEPEQEKPTTPDAEEPSTDD SPNTEEPSNDIPTSDDQPTNEDTGSSEEGTQDNGSQNDVQTNIETGQKHQESSKNVPE QDTNTENTGTSKTDFSLIELADENDGSNQSDGLQGDGADGETDISGAKKRLNEAAIKL EEIENALQEKQEEHNNKLEKHIDELNQEIKELNKTVSKLNDQIGDLTKKLVDFDNNVN DAYRLIYNLEDEIIQTLQSRGYIDQKEKLSSIFSSRIETDNISNLMKYYNSLNLYKST LNDNLDLGSLTIIKGEVIQEQDGNVQSVLALTPEESASWEALKNNTMQTDEDINSFID GMTKFADDYSGYIRDSQAGVLDELTKISESAAKASEQLVTGATQESATFSNDGLSGTM ALSVQDTVGQEVLQMSDMMGSLSDRQSGIIDYTTNMQQSVNDVQAKADTLNNNWGKNV ASTKLVRNDVYGILGNTLVDGQNNGYVYDYLANPLKISGEVPEEKIQTVPPVVILVIV LISSLLIGYFSSYYQNAPLLVKGALFGILNILVGLMISLFGLNIYSLPDDQTIKWSVF TILLLVASSAFIRTAFRFGSIPGWVASAAMILFYVAPLIDLIMPNFTFEDPVSKVYID IQYGTGHLFTMGITVLLIITVIAVALPLIIRLMAEHTAESDETYEA*" gene complement(3132285..3135515) /gene="yueB" /locus_tag="BSU_31860" /old_locus_tag="BSU31860" CDS complement(3135512..3139999) /gene="yukAB" /locus_tag="BSU_31875" /old_locus_tag="BSU31875" /function="11.1: Protein and peptide secretion and trafficking" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:15576783, 24798022" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15576783, 24798022; Product type t: transporter" /codon_start=1 /transl_table=11 /product="ESX secretion system FtsK/SpoIIIE family ATPase" /protein_id="NP_391066.2" /db_xref="EnsemblGenomes-Gn:BSU31875" /db_xref="EnsemblGenomes-Tr:CAB15176" /db_xref="GOA:C0SPA7" /db_xref="InterPro:IPR002543" /db_xref="InterPro:IPR022206" /db_xref="InterPro:IPR023839" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG12375" /db_xref="UniProtKB/Swiss-Prot:C0SPA7" /translation="MSLLWVFYQNNVQKLNLSNLPSSHPVTIGPDVKDSVTISTIPFN SGVISLKRKESGGQYEVFLGNDCLGTIETDISFTLQTDQQDIRLILTGSEPEKSVYFT GNRDEIVCSSEKTNADIYLNPQDFAFAEQSTFSLLRAGGSWSVRPESGTIFLNGEKIN ANTPLKPGDEIFWNFTQMRVTEQDLLEIVHYAQFETALTETVKPSTEMQKKYPQYRRT PRMVYDLPDDRVSFSFPSQESDQTNRGLWLVILPPLVMLIVMGVVAIIQPRGIFILVS LAMFMMTLITSTVQYFRDKNQRKKREEKRERVYKLYLDNKRKELQALAEKQKQVLEFH FPSFEQMKYLTSEISDRIWEKSLESKDYLQLRLGTGTVPSSYEINMSGGDLANRDIDD LMEKSQHMQRVYKDIRNAPVTVDLAEGPMGLVGKSQIVKNEIHQLIGQLSFFNSYHDL RFVFIFHEEEYKDWEWMKWLPQFQMPHIYAKGFIYNEQTRDQLLSSLYELIRERDLED DKEKLQFKPHFVFVITNQQLISEHVILEYLEGQHEHLGISTIVAAETKESLSENITTL VRYINEHEGDILIQKKKAVRIPFRLDHHQREDNERFSRTLRTLNHQVGITNSIPETVS FLELFHAKEVKEIGIQQRWLTSESSKSLSVPIGYKGKDDIVYLNLHEKAHGPHGLLAG TTGSGKSEFLQTYILSLAVHFHPHEAAFLLIDYKGGGMAQPFRNIPHLLGTITNIEGS KNFSMRALASIKSELKKRQRLFDQYQVNHINDYTKLYKQGKAEVAMPHLFLISDEFAE LKSEEPDFIRELVSAARIGRSLGVHLILATQKPGGIIDDQIWSNSRFKVALKVQDATD SKEILKNSDAANITVTGRGYLQVGNNEVYELFQSAWSGAPYLEEVYGTEDEIAIVTDT GLIPLSEVDTEDNAKKDVQTEIEAVVDEIERIQDEMGIEKLPSPWLPPLAERIPRTLF PSNEKDHFHFAYVDEPDLQRQAPIAYKMMEDGNIGIFGSSGYGKSIAAATFLMSFADV YTPEELHVYIFDFGNGTLLPLAKLPHTADYFLMDQSRKIEKFMIRIKEEIDRRKRLFR EKEISHIKMYNALSEEELPFIFITIDNFDIVKDEMHELESEFVQLSRDGQSLGIYFML TATRVNAVRQSLLNNLKTKIVHYLMDQSEGYSIYGRPKFNLEPIPGRVIIQKEELYFA QMFLPVDADDDIGMFNELKSDVQKLQGRFASMEQPAPIPMLPESLSTRELSIRFKLER KPLSVPIGLHEETVSPVYFDLGKHKHCLILGQTQRGKTNVLKVMLEHLIDDETEMIGL FDSIDRGLSHYAKESDVSYLETKEDIEQWIETAEDIFKTREAMYVEAVRQGDAQNLRF SQVVLMIDGITRFQQTIDTRIQDRLANFMKSYAHLGFSFIPGGNHSEFSKGYDSLTTE MKQIRHAILLMKKSEQNVIPLPYQRQEPEIQPGFGYVVENGKEQKVQIPLCSAERESA R*" gene complement(3135512..3139999) /gene="yukAB" /locus_tag="BSU_31875" /old_locus_tag="BSU31875" promotor_-35 3139274..3139280 /Source="Nicolas_upshift_promotors" /id="U2486" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=203 /SigmaFactorBS="cggaggcaggatgacgagccacagccctctgttGGTTTGAtc gctctcctgagaGGGAAAACTGAAAGAAACGcggtcatccggcagatcgtataccatc c" /listShort="S1225" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3139295..3139313 /Source="Nicolas_upshift_promotors" /id="U2486" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=203 /SigmaFactorBS="cggaggcaggatgacgagccacagccctctgttGGTTTGAtc gctctcctgagaGGGAAAACTGAAAGAAACGcggtcatccggcagatcgtataccatc c" /listShort="S1225" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 3139301..3140263 /Source="Nicolas_S_feature" /locus_tag="new_3273703_3274665" /HighExp="Etha, Sw, Gly, Salt, B60, M9-stat, LoTm, T0.30H, BT, LPhT" /AntisenseName="yukB" /AntisenseCor="-0.26212584196591598" /AntisenseRegPval="-4.9000000000000004" /CDS_PredictionProba="NA" /TUshortSig="SigB" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1225" upshifts 3139301 /Source="Nicolas_upshifts" /id="U2486" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=203 /SigmaFactorBS="cggaggcaggatgacgagccacagccctctgttGGTTTGAtc gctctcctgagaGGGAAAACTGAAAGAAACGcggtcatccggcagatcgtataccatc c" /listShort="S1225" /GFF_Attribute="listLong" CDS complement(3140060..3141415) /gene="yukC" /locus_tag="BSU_31890" /old_locus_tag="BSU31890" /function="11.1: Protein and peptide secretion and trafficking" /function="16.6: Maintain" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:15576783, 16845009, 24798022" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15576783, 16845009, 24798022; Product type t: transporter" /codon_start=1 /transl_table=11 /product="ESX secretion system YukC protein" /protein_id="NP_391067.1" /db_xref="EnsemblGenomes-Gn:BSU31890" /db_xref="EnsemblGenomes-Tr:CAB15177" /db_xref="GOA:P71070" /db_xref="InterPro:IPR018778" /db_xref="SubtiList:BG12376" /db_xref="UniProtKB/Swiss-Prot:P71070" /translation="MSGEQKSYLENQLEAVAEKTDAGYTFTFQREKIKLLDGLEANVI KDINPFFHKEIDVTDDEVIITIQPPSSYKAFRFMKAKDKKSKWQFAYQLVQAVQQHNL SRLNLIVAPENIVFDKGLTPYFLHYGVKESIPPYERDEERVWQELKAAAALAVDGAFA FEDYLKFNETLTFSAEAKAILDAESYDDLLELIQTHIDELEAKAKTYIHIPRKKWNIQ RYIGLGLIVLLVPALIYSMYALFFAQPKHQAIVDSNRAFLNKQYSEVISTLSKYDAES LPESVQYQLATSYVEVENLGSAKTKNIENNLVTLQSDPQHFLYWIDYGRGEYKEAISI GRKLEYNDYIYFALAKYKQQLLSEDTNDEDIQKELDSVNSELEKAQKERQENKQSNSE TSLVDTSEEQTQTDEEKQAEEKAAEEKAAAEEKAKKEEQKEKEDEKKETEKKDEKKDD K*" gene complement(3140060..3141415) /gene="yukC" /locus_tag="BSU_31890" /old_locus_tag="BSU31890" downshifts complement(3140081) /Source="Nicolas_upshifts" /id="D1648" /incds=0 /nref=5 /ntot=116 /MaxReadThrough="6.33518" /MaxDrop="3.1562" /score="14.9475399" /energy="-16" /TU="U2488" /idTUdmin="U2496" /TUdmin=5823 /isTUend="FALSE" CDS complement(3141430..3141669) /gene="yukD" /locus_tag="BSU_31900" /old_locus_tag="BSU31900" /function="11.1: Protein and peptide secretion and trafficking" /function="16.5: Explore" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:15576783, 16845009, 24798022" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15576783, 16845009, 24798022; Product type t: transporter" /codon_start=1 /transl_table=11 /product="ESX secretion system YukD protein" /protein_id="NP_391068.1" /db_xref="EnsemblGenomes-Gn:BSU31900" /db_xref="EnsemblGenomes-Tr:CAB15178" /db_xref="InterPro:IPR014921" /db_xref="InterPro:IPR024962" /db_xref="InterPro:IPR029071" /db_xref="PDB:2BPS" /db_xref="SubtiList:BG12377" /db_xref="UniProtKB/Swiss-Prot:P71071" /translation="MYIDITIDLKHYNGSVFDLRLSDYHPVKKVIDIAWQAQSVSMPP REGHWIRVVNKDKVFSGECKLSDCGITNGDRLEIL*" gene complement(3141430..3141669) /gene="yukD" /locus_tag="BSU_31900" /old_locus_tag="BSU31900" CDS complement(3141739..3142032) /gene="yukE" /locus_tag="BSU_31910" /old_locus_tag="BSU31910" /function="11.1: Protein and peptide secretion and trafficking" /experiment="publication(s) with functional evidences, PMID:11973144, 15576783, 22720735, 24798022, 24828531" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11973144, 15576783, 22720735, 24798022, 24828531; Product type t : transporter" /codon_start=1 /transl_table=11 /product="small WGX100 secreted protein (ESX-dependent secretion)" /protein_id="NP_391069.2" /db_xref="EnsemblGenomes-Gn:BSU31910" /db_xref="EnsemblGenomes-Tr:CAB15179" /db_xref="GOA:C0SP85" /db_xref="InterPro:IPR010310" /db_xref="InterPro:IPR036689" /db_xref="SubtiList:BG12378" /db_xref="UniProtKB/Swiss-Prot:C0SP85" /translation="MAGLIRVTPEELRAMAKQYGVESQEVLNQVDRLNRMISDLKSMW EGASSEAFADQYEQLKPSFIKMSDLLQDVNQQLDQTANTLESTDQDIANQIRG*" gene complement(3141739..3142032) /gene="yukE" /locus_tag="BSU_31910" /old_locus_tag="BSU31910" downshifts complement(3141749) /Source="Nicolas_upshifts" /id="D1649" /incds=0 /nref=248 /ntot=268 /MaxReadThrough="6.21938" /MaxDrop="7.50121" /score="14.9475399" /energy="-16" /TU="U2488" /idTUdmin="U2496" /TUdmin=4155 /isTUend="FALSE" downshifts 3142026 /Source="Nicolas_upshifts" /id="D1650" /incds=0 /nref=1 /ntot=26 /MaxReadThrough="2.85718" /MaxDrop="3.33739" /score="43.0917981" /energy="-17.1" /TU="NA" /idTUdmin="U2487" /TUdmin="-242" /isTUend="FALSE" S_feature complement(3142033..3142111) /Source="Nicolas_S_feature" /locus_tag="new_3276435_3276513_c" /HighExp="T-1.10H, T1.0H, T-0.40H, T1.30H, BI, T2.30H, T3.0H, T-2.40H, T2.0H, T-1.40H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1226" promotor_-35 3142074..3142081 /Source="Nicolas_upshift_promotors" /id="U2487" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.485514485514486" /psig="0.76023976023976" /xcortree=715 /SigmaFactorBS="tattcctcattacctcctgtgccatcagcctaaatatgggct AATTCACTtatttttagaacgtCATTATTATAAAAACAGTttttcggcatagtcaaac a" /listShort="S1227" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(3142091..3142110) /Source="Nicolas_upshift_promotors" /id="U2488" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.735264735264735" /psig=1 /xcortree=3086 /SigmaFactorBS="gtaaaccattggactcattttgtaaaattaaaacatattTGT TTGACtatgccgaaaaactGTTTTTATAATAATGACGTTctaaaaataagtgaattag c" /listShort="S1226, yukE, yukD, yukC, yukB, yueB, yueC, yueD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3142092 /Source="Nicolas_upshifts" /id="U2487" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.485514485514486" /psig="0.76023976023976" /xcortree=715 /SigmaFactorBS="tattcctcattacctcctgtgccatcagcctaaatatgggct AATTCACTtatttttagaacgtCATTATTATAAAAACAGTttttcggcatagtcaaac a" /listShort="S1227" /GFF_Attribute="listLong" promotor_-10 3142096..3142113 /Source="Nicolas_upshift_promotors" /id="U2487" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.485514485514486" /psig="0.76023976023976" /xcortree=715 /SigmaFactorBS="tattcctcattacctcctgtgccatcagcctaaatatgggct AATTCACTtatttttagaacgtCATTATTATAAAAACAGTttttcggcatagtcaaac a" /listShort="S1227" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3142111) /Source="Nicolas_upshifts" /id="U2488" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.735264735264735" /psig=1 /xcortree=3086 /SigmaFactorBS="gtaaaccattggactcattttgtaaaattaaaacatattTGT TTGACtatgccgaaaaactGTTTTTATAATAATGACGTTctaaaaataagtgaattag c" /listShort="S1226, yukE, yukD, yukC, yukB, yueB, yueC, yueD" /GFF_Attribute="listLong" promotor_-35 complement(3142125..3142132) /Source="Nicolas_upshift_promotors" /id="U2488" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.735264735264735" /psig=1 /xcortree=3086 /SigmaFactorBS="gtaaaccattggactcattttgtaaaattaaaacatattTGT TTGACtatgccgaaaaactGTTTTTATAATAATGACGTTctaaaaataagtgaattag c" /listShort="S1226, yukE, yukD, yukC, yukB, yueB, yueC, yueD" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 3142170..3142175 /Source="Nicolas_upshift_promotors" /id="U2489" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.523476523476524" /psig="0.523476523476524" /xcortree=769 /SigmaFactorBS="taattttacaaaatgagtccaatggtttACCCCGaatcactc aaaaatGACATATACTGTAAAGTAAAtaggtttattttcttaatcttctcttcattct c" /listShort="S1227" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3142190..3142209 /Source="Nicolas_upshift_promotors" /id="U2489" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.523476523476524" /psig="0.523476523476524" /xcortree=769 /SigmaFactorBS="taattttacaaaatgagtccaatggtttACCCCGaatcactc aaaaatGACATATACTGTAAAGTAAAtaggtttattttcttaatcttctcttcattct c" /listShort="S1227" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 3142202..3142308 /Source="Nicolas_S_feature" /locus_tag="new_3276604_3276710" /HighExp="S8, C30, S7, S6, Pyr, Glucon, B60, LoTm, C90, M/G" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigK, SigA" /TUshortPSig="0.523, 0.76" /TUlongSig="NA" /TUlongPSig="NA" /label="S1227" upshifts 3142202 /Source="Nicolas_upshifts" /id="U2489" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.523476523476524" /psig="0.523476523476524" /xcortree=769 /SigmaFactorBS="taattttacaaaatgagtccaatggtttACCCCGaatcactc aaaaatGACATATACTGTAAAGTAAAtaggtttattttcttaatcttctcttcattct c" /listShort="S1227" /GFF_Attribute="listLong" promotor_-35 3142377..3142383 /Source="Nicolas_upshift_promotors" /id="U2490" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.418581418581419" /psig="0.81918081918082" /xcortree=1909 /SigmaFactorBS="tctttccttaattagtcttgcctccgatgactttcttAGAAG ATtaataggataagcTGTCGTATTATATGAGACATacactgtcctgcaaaaaggcgat t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3142397..3142416 /Source="Nicolas_upshift_promotors" /id="U2490" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.418581418581419" /psig="0.81918081918082" /xcortree=1909 /SigmaFactorBS="tctttccttaattagtcttgcctccgatgactttcttAGAAG ATtaataggataagcTGTCGTATTATATGAGACATacactgtcctgcaaaaaggcgat t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3142400 /Source="Nicolas_upshifts" /id="U2490" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.418581418581419" /psig="0.81918081918082" /xcortree=1909 /SigmaFactorBS="tctttccttaattagtcttgcctccgatgactttcttAGAAG ATtaataggataagcTGTCGTATTATATGAGACATacactgtcctgcaaaaaggcgat t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 3142505..3142508 /Source="Nicolas_upshift_promotors" /id="U2491" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.779220779220779" /psig="0.96103896103896" /xcortree=3188 /SigmaFactorBS="atagaacgtttctctcatgaaattgtttttttgcttctgttc tttgttGTTGattttcacaaacaacAACAATCATAATAAAAGGAAggggatgagatgt c" /listShort="yukF" /listLong="ald" /label="promotor_-35" upshifts 3142517 /Source="Nicolas_upshifts" /id="U2491" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.779220779220779" /psig="0.96103896103896" /xcortree=3188 /SigmaFactorBS="atagaacgtttctctcatgaaattgtttttttgcttctgttc tttgttGTTGattttcacaaacaacAACAATCATAATAAAAGGAAggggatgagatgt c" /listShort="yukF" /listLong="ald" promotor_-10 complement(3142520..3142539) /Source="Nicolas_upshift_promotors" /id="U2492" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.564435564435564" /psig="0.98901098901099" /xcortree=2439 /SigmaFactorBS="ggcatggtcataaatctccctacttttcgtgcttgatttctC TTTGACAtctcatccccttccTTTTATTATGATTGTTGTTGtttgtgaaaatcaacaa c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-10 3142524..3142543 /Source="Nicolas_upshift_promotors" /id="U2491" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.779220779220779" /psig="0.96103896103896" /xcortree=3188 /SigmaFactorBS="atagaacgtttctctcatgaaattgtttttttgcttctgttc tttgttGTTGattttcacaaacaacAACAATCATAATAAAAGGAAggggatgagatgt c" /listShort="yukF" /listLong="ald" /label="promotor_-10" upshifts complement(3142542) /Source="Nicolas_upshifts" /id="U2492" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.564435564435564" /psig="0.98901098901099" /xcortree=2439 /SigmaFactorBS="ggcatggtcataaatctccctacttttcgtgcttgatttctC TTTGACAtctcatccccttccTTTTATTATGATTGTTGTTGtttgtgaaaatcaacaa c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" CDS 3142553..3143821 /gene="adeR" /locus_tag="BSU_31920" /old_locus_tag="BSU31920" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:22797752" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 22797752; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional activator (AdeR-alanine)" /protein_id="NP_391070.2" /db_xref="EnsemblGenomes-Gn:BSU31920" /db_xref="EnsemblGenomes-Tr:CAB15180" /db_xref="GOA:P71073" /db_xref="InterPro:IPR010312" /db_xref="InterPro:IPR025736" /db_xref="InterPro:IPR029016" /db_xref="SubtiList:BG12379" /db_xref="UniProtKB/Swiss-Prot:P71073" /translation="MSKRNQARKVGRFMTMPNDPFKYSFDRLEDVADHISDVLRCPIT IEDVNHKLLAYSTHSDCTDPARTSTIIGRRVPEKVINKLWKDGTIPALLKTDQPIRVK QIDEVGLSNRVAISIWKNKQVLGFIWALEIQKTLSDEDLLTLQMAAKAVKNKLLKLQI RKTKNEERSQEFFWKMLTGHIHQEDDMADGFHKLGMAAPSEFSVMIIRINGELTEKIE QQLQYLQETTQQVYVLLATVDSNELIILTSPKTDHPFQDLKQFALSTQKQLKERYKIE DVSIAFGGIYNSISFVSRSYQEALSVLKTKERFAEETKHLFSFSELGIYQYLDVLNEK RKQAGHYNYSLSKLEQYDRDHQSNMVETLERFIEADSNVNTASKLLNIHVNTLNYRLK RISQIAEIDLKNVNQKFTIYLDIKLRHMDL*" gene 3142553..3143821 /gene="adeR" /locus_tag="BSU_31920" /old_locus_tag="BSU31920" promotor_-35 complement(3142554..3142561) /Source="Nicolas_upshift_promotors" /id="U2492" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.564435564435564" /psig="0.98901098901099" /xcortree=2439 /SigmaFactorBS="ggcatggtcataaatctccctacttttcgtgcttgatttctC TTTGACAtctcatccccttccTTTTATTATGATTGTTGTTGtttgtgaaaatcaacaa c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" misc_feature 3143881..3143900 /Source="Nicolas_upshift_promotors" /id="U2493" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.696303696303696" /psig="0.996003996003996" /xcortree=1594 /SigmaFactorBS="tcacaaatccatgtttttttattttcttaatcaaacaaagaa ttttccaaaatatCAAGCTACACTAAAAATATCacatatacaggaggagacagatatg a" /listShort="ald, yukJ" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 3143886 /Source="Nicolas_upshifts" /id="U2493" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.696303696303696" /psig="0.996003996003996" /xcortree=1594 /SigmaFactorBS="tcacaaatccatgtttttttattttcttaatcaaacaaagaa ttttccaaaatatCAAGCTACACTAAAAATATCacatatacaggaggagacagatatg a" /listShort="ald, yukJ" /GFF_Attribute="listLong" CDS 3143923..3145059 /gene="ald" /locus_tag="BSU_31930" /old_locus_tag="BSU31930" /EC_number="1.4.1.1" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:488097, 8226620, 22720735, 22797752, 26202482" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 488097, 8226620, 22720735, 22797752, 26202482; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="L-alanine dehydrogenase (NAD-dependent)" /protein_id="NP_391071.1" /db_xref="EnsemblGenomes-Gn:BSU31930" /db_xref="EnsemblGenomes-Tr:CAB15181" /db_xref="GOA:Q08352" /db_xref="InterPro:IPR007698" /db_xref="InterPro:IPR007886" /db_xref="InterPro:IPR008141" /db_xref="InterPro:IPR008142" /db_xref="InterPro:IPR008143" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG10468" /db_xref="UniProtKB/Swiss-Prot:Q08352" /translation="MIIGVPKEIKNNENRVALTPGGVSQLISNGHRVLVETGAGLGSG FENEAYESAGAEIIADPKQVWDAEMVMKVKEPLPEEYVYFRKGLVLFTYLHLAAEPEL AQALKDKGVTAIAYETVSEGRTLPLLTPMSEVAGRMAAQIGAQFLEKPKGGKGILLAG VPGVSRGKVTIIGGGVVGTNAAKMAVGLGADVTIIDLNADRLRQLDDIFGHQIKTLIS NPVNIADAVAEADLLICAVLIPGAKAPTLVTEEMVKQMKPGSVIVDVAIDQGGIVETV DHITTHDQPTYEKHGVVHYAVANMPGAVPRTSTIALTNVTVPYALQIANKGAVKALAD NTALRAGLNTANGHVTYEAVARDLGYEYVPAEKALQDESSVAGA*" gene 3143923..3145059 /gene="ald" /locus_tag="BSU_31930" /old_locus_tag="BSU31930" downshifts 3145059 /Source="Nicolas_upshifts" /id="D1651" /incds=0 /nref=42 /ntot=190 /MaxReadThrough="5.86626" /MaxDrop="4.4689" /score="41.2794059" /energy="-14.2" /TU="U2493" /idTUdmin="U2493" /TUdmin="-769" /isTUend="FALSE" promotor_-35 3145108..3145116 /Source="Nicolas_upshift_promotors" /id="U2494" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp=1 /psig=1 /xcortree=521 /SigmaFactorBS="ataagcttgcagaaagatttctgcaggcttttttatttttta AAAGGAAAAaagagaccattTCACGAATTATGACTATGAagttgatcataaaggagga t" /listShort="yukJ" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 3145126 /Source="Nicolas_upshifts" /id="U2494" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp=1 /psig=1 /xcortree=521 /SigmaFactorBS="ataagcttgcagaaagatttctgcaggcttttttatttttta AAAGGAAAAaagagaccattTCACGAATTATGACTATGAagttgatcataaaggagga t" /listShort="yukJ" /GFF_Attribute="listLong" promotor_-10 3145128..3145146 /Source="Nicolas_upshift_promotors" /id="U2494" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp=1 /psig=1 /xcortree=521 /SigmaFactorBS="ataagcttgcagaaagatttctgcaggcttttttatttttta AAAGGAAAAaagagaccattTCACGAATTATGACTATGAagttgatcataaaggagga t" /listShort="yukJ" /GFF_Attribute="listLong" /label="promotor_-10" CDS 3145171..3145848 /gene="yukJ" /locus_tag="BSU_31945" /old_locus_tag="BSU31945" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_391073.2" /db_xref="EnsemblGenomes-Gn:BSU31945" /db_xref="EnsemblGenomes-Tr:CAB15183" /db_xref="InterPro:IPR019268" /db_xref="SubtiList:BG12380" /db_xref="UniProtKB/Swiss-Prot:C0SPB1" /translation="MAVQQYGVLKGIVLDMKRETDDDSPHFQVKMLGEENTYYRCAIN VMSSSEESEVLYLADDQFDSGSITILPNMPYGYTRINEANREVALDYVRGNLFDPREM KPLPHEITGPDNDLNDFIETYMKKAQDEKTPVYIFGSKFGPEQAADKIFGFTPTNGMH NIHMNQGNAMDTRWKKDNGSWHDGGILIQFADQWAAVFLAFLSQSWCTDENGNPVRDC DHTQTSA*" gene 3145171..3145848 /gene="yukJ" /locus_tag="BSU_31945" /old_locus_tag="BSU31945" downshifts 3145832 /Source="Nicolas_upshifts" /id="D1652" /incds=0 /nref=37 /ntot=185 /MaxReadThrough="3.39608" /MaxDrop="5.40829" /score="9.49891506" /energy="-12" /TU="U2494" /idTUdmin="U2493" /TUdmin=4 /isTUend="TRUE" CDS complement(3145892..3146101) /gene="mbtH" /locus_tag="BSU_31959" /old_locus_tag="BSU31959" /function="16.11: Scavenge (Catabolism)" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 11112781, 20845982, 21890635, 24975514, 28880538; Product type r: regulator" /codon_start=1 /transl_table=11 /product="stimulator of DhbF tyrosine adenylation activity" /protein_id="YP_003097779.1" /db_xref="EnsemblGenomes-Gn:BSU31959" /db_xref="EnsemblGenomes-Tr:CAX52685" /db_xref="InterPro:IPR005153" /db_xref="UniProtKB/Swiss-Prot:C0H3Q6" /translation="MANPFENADGTYLVLVNEEGQYSLWPGFIDVPSGWTVVHEQKGR EACLDYIQSHWSDMRPNSLKTVENV*" gene complement(3145892..3146101) /gene="mbtH" /locus_tag="BSU_31959" /old_locus_tag="BSU31959" downshifts complement(3145904) /Source="Nicolas_upshifts" /id="D1653" /incds=0 /nref=106 /ntot=174 /MaxReadThrough="1.39981" /MaxDrop="6.23998" /score="17.380299" /energy="-12" /TU="NA" /idTUdmin="U2496" /TUdmin=0 /isTUend="TRUE" CDS complement(3146117..3153253) /gene="dhbF" /locus_tag="BSU_31960" /old_locus_tag="BSU31960" /EC_number="2.7.7.-" /EC_number="5.1.1.-" /function="16.2: Construct biomass (Anabolism)" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:11112781, 12354229, 16672620, 18957859, 26284661, 27731335" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11112781, 12354229, 16672620, 18957859, 26284661, 27731335; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="siderophore 2,3-dihydroxybenzoate-glycine-threonine trimeric ester bacillibactin synthetase" /protein_id="NP_391076.3" /db_xref="EnsemblGenomes-Gn:BSU31960" /db_xref="EnsemblGenomes-Tr:CAB15186" /db_xref="GOA:P45745" /db_xref="InterPro:IPR000873" /db_xref="InterPro:IPR001031" /db_xref="InterPro:IPR001242" /db_xref="InterPro:IPR009081" /db_xref="InterPro:IPR010071" /db_xref="InterPro:IPR020802" /db_xref="InterPro:IPR020806" /db_xref="InterPro:IPR020845" /db_xref="InterPro:IPR025110" /db_xref="InterPro:IPR029058" /db_xref="InterPro:IPR036736" /db_xref="SubtiList:BG11243" /db_xref="UniProtKB/Swiss-Prot:P45745" /translation="MPDTKDLQYSLTGAQTGIWFAQQLDPDNPIYNTAEYIEINGPVN IALFEEALRHVIKEAESLHVRFGENMDGPWQMINPSPDVQLHVIDVSSEPDPEKTALN WMKADLAKPVDLGYAPLFNEALFIAGPDRFFWYQRIHHIAIDGFGFSLIAQRVASTYT ALIKGQTAKSRSFGSLQAILEEDTDYRGSEQYEKDRQFWLDRFADAPEVVSLADRAPR TSNSFLRHTAYLPPSDVNALKEAARYFSGSWHEVMIAVSAVYVHRMTGSEDVVLGLPM MGRIGSASLNVPAMVMNLLPLRLTVSSSMSFSELIQQISREIRSIRRHHKYRHEELRR DLKLIGENHRLFGPQINLMPFDYGLDFAGVRGTTHNLSAGPVDDLSINVYDRTDGSGL RIDVDANPEVYSESDIKLHQQRILQLLQTASAGEDMLIGQMELLLPEEKEKVISKWNE TAKSEKLVSLQDMFEKQAVLTPERIALMCDDIQVNYRKLNEEANRLARLLIEKGIGPE QFVALALPRSPEMVASMLGVLKTGAAYLPLDPEFPADRISYMLEDAKPSCIITTEEIA ASLPDDLAVPELVLDQAVTQEIIKRYSPENQDVSVSLDHPAYIIYTSGSTGRPKGVVV TQKSLSNFLLSMQEAFSLGEEDRLLAVTTVAFDISALELYLPLISGAQIVIAKKETIR EPQALAQMIENFDINIMQATPTLWHALVTSEPEKLRGLRVLVGGEALPSGLLQELQDL HCSVTNLYGPTETTIWSAAAFLEEGLKGVPPIGKPIWNTQVYVLDNGLQPVPPGVVGE LYIAGTGLARGYFHRPDLTAERFVADPYGPPGTRMYRTGDQARWRADGSLDYIGRADH QIKIRGFRIELGEIDAVLANHPHIEQAAVVVREDQPGDKRLAAYVVADAAIDTAELRR YMGASLPDYMVPSAFVEMDELPLTPNGKLDRKALPAPDFSTSVSDRAPRTPQEEILCD LFAEVLGLARVGIDDSFFELGGHSLLAARLMSRIREVMGAELGIAKLFDEPTVAGLAA HLDLAQSACPALQRAERPEKIPLSFAQRRLWFLHCLEGPSPTYNIPVAVRLSGELDQG LLKAALYDLVCRHESLRTIFPESQGTSYQHILDADRACPELHVTEIAEKELSDRLAEA VRYSFDLAAEPAFRAELFVIGPDEYVLLLLVHHIVGDGWSLTPLTRDLGTAYAARCHG RSPEWAPLAVQYADYALWQQELLGNEDDPNSLIAGQLAFWKETLKNLPDQLELPTDYS RPAEPSHDGDTIHFRIEPEFHKRLQELARANRVSLFMVLQSGLAALLTRLGAGTDIPI GSPIAGRNDDALGDLVGLFINTLVLRTDTSGDPSFRELLDRVREVNLAAYDNQDLPFE RLVEVLNPARSRATHPLFQIMLAFQNTPDAELHLPDMESSLRINSVGSAKFDLTLEIS EDRLADGTPNGMEGLLEYSTDLFKRETAQALADRLMRLLEAAESDPDEQIGNLDILAP EEHSSMVTDWQSVSEKIPHACLPEQFEKQAALRPDAIAVVYENQELSYAELNERANRL ARMMISEGVGPEQFVALALPRSLEMAVGLLAVLKAGAAYLPLDPDYPADRIAFMLKDA QPAFIMTNTKAANHIPPVENVPKIVLDDPELAEKLNTYPAGNPKNKDRTQPLSPLNTA YVIYTSGSTGVPKGVMIPHQNVTRLFAATEHWFRFSSGDIWTMFHSYAFDFSVWEIWG PLLHGGRLVIVPHHVSRSPEAFLRLLVKEGVTVLNQTPSAFYQFMQAEREQPDLGQAL SLRYVIFGGEALELSRLEDWYNRHPENRPQLINMYGITETTVHVSYIELDRSMAALRA NSLIGCGIPDLGVYVLDERLQPVPPGVAGELYVSGAGLARGYLGRPGLTSERFIADPF GPPGTRMYRTGDVARLRADGSLDYVGRADHQVKIRGFRIELGEIEAALVQHPQLEDAA VIVREDQPGDKRLAAYVIPSEETFDTAELRRYAAERLPDYMVPAAFVTMKELPLTPNG KLDRKALPAPDFAAAVTGRGPRTPQEEILCDLFMEVLHLPRVGIDDRFFDLGGHSLLA VQLMSRIREALGVELSIGNLFEAPTVAGLAERLEMGSSQSALDVLLPLRTSGDKPPLF CVHPAGGLSWCYAGLMTNIGTDYPIYGLQARGIGQREELPKTLDDMAADYIKQIRTVQ PKGPYHLLGWSLGGNVVQAMATQLQNQGEEVSLLVMLDAYPNHFLPIKEAPDDEEALI ALLALGGYDPDSLGEKPLDFEAAIEILRRDGSALASLDETVILNLKNTYVNSVGILGS YKPKTFRGNVLFFRSTIIPEWFDPIEPDSWKPYINGQIEQIDIDCRHKDLCQPEPLAQ IGKVLAVKLEELNK*" gene complement(3146117..3153253) /gene="dhbF" /locus_tag="BSU_31960" /old_locus_tag="BSU31960" CDS complement(3153273..3154211) /gene="dhbB" /locus_tag="BSU_31970" /old_locus_tag="BSU31970" /EC_number="3.3.2.1" /function="16.2: Construct biomass (Anabolism)" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 8921902, 9214294, 11112781, 11790741, 12354229, 16672620, 26284661; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="isochorismatase (siderophore specific)" /protein_id="NP_391077.1" /db_xref="EnsemblGenomes-Gn:BSU31970" /db_xref="EnsemblGenomes-Tr:CAB15187" /db_xref="GOA:P45743" /db_xref="InterPro:IPR000868" /db_xref="InterPro:IPR009081" /db_xref="InterPro:IPR016291" /db_xref="InterPro:IPR036380" /db_xref="InterPro:IPR036736" /db_xref="SubtiList:BG11241" /db_xref="UniProtKB/Swiss-Prot:P45743" /translation="MAIPAIQPYQMPTASDMPQNKVSWVPDPNRAVLLIHDMQNYFVD AFTAGASPVTELSANIRKLKNQCVQLGIPVVYTAQPGSQNPDDRALLTDFWGPGLNSG PYEEKIITELAPEDDDLVLTKWRYSAFKRTNLLEMMRKEGRDQLIITGIYAHIGCLVT ACEAFMEDIKAFFVGDAVADFSLEKHQMALEYAAGRCAFTVMTDSLLDQLQNAPADVQ KTSANTGKKNVFTCENIRKQIAELLQETPEDITDQEDLLDRGLDSVRIMTLVEQWRRE GAEVTFVELAERPTIEEWQKLLTTRSQQVLPNADYL*" gene complement(3153273..3154211) /gene="dhbB" /locus_tag="BSU_31970" /old_locus_tag="BSU31970" CDS complement(3154239..3155858) /gene="dhbE" /locus_tag="BSU_31980" /old_locus_tag="BSU31980" /EC_number="2.7.7.58" /EC_number="6.3.2.-" /function="16.2: Construct biomass (Anabolism)" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:8921902, 9214294, 11112781, 11790741, 12354229, 12221282, 16672620, 16403027, 23352143, 26284661" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8921902, 9214294, 11112781, 11790741, 12354229, 12221282, 16672620, 16403027, 23352143, 26284661; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="2,3-dihydroxybenzoate-AMP ligase" /protein_id="NP_391078.1" /db_xref="EnsemblGenomes-Gn:BSU31980" /db_xref="EnsemblGenomes-Tr:CAB15188" /db_xref="GOA:P40871" /db_xref="InterPro:IPR000873" /db_xref="InterPro:IPR011963" /db_xref="InterPro:IPR020845" /db_xref="InterPro:IPR025110" /db_xref="PDB:1MD9" /db_xref="PDB:1MDB" /db_xref="PDB:1MDF" /db_xref="SubtiList:BG11020" /db_xref="UniProtKB/Swiss-Prot:P40871" /translation="MLKGFTPWPDELAETYRKNGCWAGETFGDLLRDRAAKYGDRIAI TCGNTHWSYRELDTRADRLAAGFQKLGIQQMDRVVVQLPNIKEFFEVIFALFRLGALP VFALPSHRSSEITYFCEFAEAAAYIIPDAYSGFDYRSLARQVQSKLPTLKNIIVAGEA EEFLPLEDLHAEPVKLPEVKSSDVAFLQLSGGSTGLSKLIPRTHDDYIYSLKRSVEVC WLDHSTVYLAALPMAHNYPLSSPGVLGVLYAGGRVVLSPSPSPDDAFPLIEREKVTIT ALVPPLAMVWMDAASSRRDDLSSLQVLQVGGAKFSAEAARRVKAVFGCTLQQVFGMAE GLVNYTRLDDPEEIIVNTQGKPMSPYDEMRVWDDHDRDVKPGETGHLLTRGPYTIRGY YKAEEHNAASFTEDGFYRTGDIVRLTRDGYIVVEGRAKDQINRGGEKVAAEEVENHLL AHPAVHDAAMVSMPDQFLGERSCVFIIPRDEAPKAAELKAFLRERGLAAYKIPDRVEF VESFPQTGVGKVSKKALREAISEKLLAGFKK*" gene complement(3154239..3155858) /gene="dhbE" /locus_tag="BSU_31980" /old_locus_tag="BSU31980" CDS complement(3155887..3157083) /gene="dhbC" /locus_tag="BSU_31990" /old_locus_tag="BSU31990" /EC_number="5.4.4.2" /function="16.2: Construct biomass (Anabolism)" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1b: Function from experimental evidences in the studied species; PubMedId: 12354229, 16672620, 19777807, 26284661; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="isochorismate synthase (siderophore-specific)" /protein_id="NP_391079.2" /db_xref="EnsemblGenomes-Gn:BSU31990" /db_xref="EnsemblGenomes-Tr:CAB15189" /db_xref="GOA:P45744" /db_xref="InterPro:IPR004561" /db_xref="InterPro:IPR005801" /db_xref="InterPro:IPR015890" /db_xref="SubtiList:BG11242" /db_xref="UniProtKB/Swiss-Prot:P45744" /translation="MLDQNVITETKAEHLLHEYQPGAFFLASPHRVLLAKGICEIVPE ADGQNQMETLSGRIAEALRQAKQSGQSRPLVVGAVPFDQVKAARLVVPEEVRWSGPLQ FDHEEKEQQAGHTYHIKPVPEPEDYKNGVEQGLARIADGTLSKIVLSRSLHLTSPEPI QTDELLRHLAQHNSHGYTFAADVSSQEETSPRRTLLGASPELLVSRMGTQVVSNPLAG SRPRSNDPVEDQRRAAELLSSAKDLHEHAVVADAVAAALRPFCRTLEVPEKPSLIKTE TMWHLSSVIKGELSDPSVTALELAAALHPTPAVCGTPTDLAREAILSIEPFDRGFFTG MVGWCDDAGDGEWIVTIRCAEAEERSLRLYAGAGVVAGSKPEDELQETSAKFRTMLRA MGVDHI*" gene complement(3155887..3157083) /gene="dhbC" /locus_tag="BSU_31990" /old_locus_tag="BSU31990" promotor_-35 3156931..3156938 /Source="Nicolas_upshift_promotors" /id="U2495" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.75024975024975" /psig="0.98001998001998" /xcortree=1925 /SigmaFactorBS="acgcctctgcaattcggccagaaagggtttcCATTTGGTttt gcccgtctgccTCCGGTACAATTTCACATATgcctttcgctaacagtacacgatgagg a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3156953..3156972 /Source="Nicolas_upshift_promotors" /id="U2495" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.75024975024975" /psig="0.98001998001998" /xcortree=1925 /SigmaFactorBS="acgcctctgcaattcggccagaaagggtttcCATTTGGTttt gcccgtctgccTCCGGTACAATTTCACATATgcctttcgctaacagtacacgatgagg a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3156960 /Source="Nicolas_upshifts" /id="U2495" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.75024975024975" /psig="0.98001998001998" /xcortree=1925 /SigmaFactorBS="acgcctctgcaattcggccagaaagggtttcCATTTGGTttt gcccgtctgccTCCGGTACAATTTCACATATgcctttcgctaacagtacacgatgagg a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" CDS complement(3157109..3157894) /gene="dhbA" /locus_tag="BSU_32000" /old_locus_tag="BSU32000" /EC_number="1.3.1.28" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:12354229, 16672620, 26284661" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12354229, 16672620, 26284661; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase" /protein_id="NP_391080.2" /db_xref="EnsemblGenomes-Gn:BSU32000" /db_xref="EnsemblGenomes-Tr:CAB15190" /db_xref="GOA:P39071" /db_xref="InterPro:IPR002347" /db_xref="InterPro:IPR003560" /db_xref="InterPro:IPR020904" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG11019" /db_xref="UniProtKB/Swiss-Prot:P39071" /translation="MNAKGIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEK LEKVVSSLKAEGRHAEAFPADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIH SLSDEEWEATFSVNSTGVFNASRSVSKYMMDRRSGSIVTVGSNAAGVPRTSMAAYASS KAAAVMFTKCLGLELAEYNIRCNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKT GIPLKKLAKPSDIADAVLFLVSGQAGHITMHNLCVDGGATLGV*" gene complement(3157109..3157894) /gene="dhbA" /locus_tag="BSU_32000" /old_locus_tag="BSU32000" S_feature complement(3157895..3158004) /Source="Nicolas_S_feature" /locus_tag="new_3292297_3292406_c" /HighExp="HiOs, GM 15, B60, nit, GM 10, GM 25, B36, GM 60, dia0, Lbexp" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="1, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S1228" promotor_-10 complement(3157999..3158018) /Source="Nicolas_upshift_promotors" /id="U2496" /multdbtbs="SigA" /comp="M17" /sig="SigA" /pcomp="0.617382617382617" /psig=1 /xcortree=2114 /SigmaFactorBS="aaaaatatttgtcactgaaattataTTTGACTGtcacatgac atttGGATATGATTATTTTTATAAttgataatgataatcattatcaatagattgcgtt t" /listShort="S1228, dhbA, dhbC, dhbE, dhbB, dhbF, ybdZ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3158004) /Source="Nicolas_upshifts" /id="U2496" /multdbtbs="SigA" /comp="M17" /sig="SigA" /pcomp="0.617382617382617" /psig=1 /xcortree=2114 /SigmaFactorBS="aaaaatatttgtcactgaaattataTTTGACTGtcacatgac atttGGATATGATTATTTTTATAAttgataatgataatcattatcaatagattgcgtt t" /listShort="S1228, dhbA, dhbC, dhbE, dhbB, dhbF, ybdZ" /GFF_Attribute="listLong" S_feature complement(3158006..3158087) /Source="Nicolas_S_feature" /locus_tag="new_3292408_3292489_c" /HighExp="HiOs, B60, nit, B36, GM 45, GM 10, BI, GM 15, GM 25, Lbexp" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1229" promotor_-35 complement(3158032..3158039) /Source="Nicolas_upshift_promotors" /id="U2496" /multdbtbs="SigA" /comp="M17" /sig="SigA" /pcomp="0.617382617382617" /psig=1 /xcortree=2114 /SigmaFactorBS="aaaaatatttgtcactgaaattataTTTGACTGtcacatgac atttGGATATGATTATTTTTATAAttgataatgataatcattatcaatagattgcgtt t" /listShort="S1228, dhbA, dhbC, dhbE, dhbB, dhbF, ybdZ" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3158088..3158957) /gene="besA" /locus_tag="BSU_32010" /old_locus_tag="BSU32010" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 12354229, 16889643, 19673474, 26284661, 28283524; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="bacillibactin trilactone hydrolase" /protein_id="NP_391081.2" /db_xref="EnsemblGenomes-Gn:BSU32010" /db_xref="EnsemblGenomes-Tr:CAB15191" /db_xref="GOA:O32102" /db_xref="InterPro:IPR000801" /db_xref="InterPro:IPR029058" /db_xref="SubtiList:BG13974" /db_xref="UniProtKB/Swiss-Prot:O32102" /translation="MKEQTTDRTNGGTSNAFTIPGTEVRMMSSRNENRTYHIFISKPS TPPPPAGYPVIYLLDANSVFGTMTEAVRIQGRRPEKTGVIPAVIVGIGYETAEPFSSA RHRDFTMPTAQSKLPERPDGREWPEHGGAEGFFRFIEEDLKPEIERDYQIDKKRQTIF GHSLGGLFVLQVLLTKPDAFQTYIAGSPSIHWNKPFILKKTDHFVSLTKKNNQPINIL LAAGELEQHHKSRMNDNARELYERLAVLSEQGIRAEFCEFSGEGHISVLPVLVSRALR FALHPDGPHLSMG*" gene complement(3158088..3158957) /gene="besA" /locus_tag="BSU_32010" /old_locus_tag="BSU32010" S_feature complement(3158958..3159038) /Source="Nicolas_S_feature" /locus_tag="new_3293360_3293440_c" /HighExp="HiOs, B60, nit, GM 15, BI, B36, LoTm, T-5.40H, Lbexp, T-4.40H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1230" promotor_-10 complement(3159022..3159041) /Source="Nicolas_upshift_promotors" /id="U2497" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.653346653346653" /psig=1 /xcortree=2115 /SigmaFactorBS="ttatttgatcaaggtgccttttttattcgggaaaaaGTTGAC TTtctttggaagaaaACCTATTATTTGAGGTGTCTagttgatagtgaaaatcattatc a" /listShort="S1230, besA, S1229, S1228, dhbA, dhbC, dhbE, dhbB, dhbF, ybdZ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3159038) /Source="Nicolas_upshifts" /id="U2497" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.653346653346653" /psig=1 /xcortree=2115 /SigmaFactorBS="ttatttgatcaaggtgccttttttattcgggaaaaaGTTGAC TTtctttggaagaaaACCTATTATTTGAGGTGTCTagttgatagtgaaaatcattatc a" /listShort="S1230, besA, S1229, S1228, dhbA, dhbC, dhbE, dhbB, dhbF, ybdZ" /GFF_Attribute="listLong" promotor_-35 complement(3159055..3159062) /Source="Nicolas_upshift_promotors" /id="U2497" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.653346653346653" /psig=1 /xcortree=2115 /SigmaFactorBS="ttatttgatcaaggtgccttttttattcgggaaaaaGTTGAC TTtctttggaagaaaACCTATTATTTGAGGTGTCTagttgatagtgaaaatcattatc a" /listShort="S1230, besA, S1229, S1228, dhbA, dhbC, dhbE, dhbB, dhbF, ybdZ" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3159171..3159767) /gene="yuiH" /locus_tag="BSU_32020" /old_locus_tag="BSU32020" /EC_number="1.7.3.-" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 11598126, 16341843, 21190336; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative molybdopterin containing enzyme subunit" /protein_id="NP_391082.1" /db_xref="EnsemblGenomes-Gn:BSU32020" /db_xref="EnsemblGenomes-Tr:CAB15192" /db_xref="GOA:O32103" /db_xref="InterPro:IPR000572" /db_xref="InterPro:IPR036374" /db_xref="SubtiList:BG13973" /db_xref="UniProtKB/Swiss-Prot:O32103" /translation="MYFGKTRQSDQSGRVPPNQNVTTSFPVLHTGDVPYYEDMTKWNL QVYGLVDHPMLLSFEDVKAFPRYESKNDIHCVTGWSRLDNVWQGVRACDIAEKAGVKE EAGYVILHAEEGWTTNLPLDDFLAETSLLAYAHNGEPLTPEHGFPLRGVFPHLYFWKS AKWLRGIQFTKENHPGFWERNGYHMRGDPWQNQRFTWD*" gene complement(3159171..3159767) /gene="yuiH" /locus_tag="BSU_32020" /old_locus_tag="BSU32020" S_feature complement(3159768..3159852) /Source="Nicolas_S_feature" /locus_tag="new_3294170_3294254_c" /HighExp="H2O2, Paraq, Cold, dia15, G135, B36, G180, B60, LoTm, G150" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="Sig-" /TUshortPSig="0.204" /TUlongSig="NA" /TUlongPSig="NA" /label="S1231" promotor_-35 3159803..3159810 /Source="Nicolas_upshift_promotors" /id="U2498" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.997002997002997" /psig=1 /xcortree=2920 /SigmaFactorBS="aaatacatatgggcctcctttttgttaacctaatttaaaatc aTGTTGACAatctttttgttcttTATTACTCTATGATTGTGTAtgtcaacctaagggg g" /listShort="bioYB" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 3159820 /Source="Nicolas_upshifts" /id="U2498" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.997002997002997" /psig=1 /xcortree=2920 /SigmaFactorBS="aaatacatatgggcctcctttttgttaacctaatttaaaatc aTGTTGACAatctttttgttcttTATTACTCTATGATTGTGTAtgtcaacctaagggg g" /listShort="bioYB" /GFF_Attribute="listLong" promotor_-10 3159825..3159844 /Source="Nicolas_upshift_promotors" /id="U2498" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.997002997002997" /psig=1 /xcortree=2920 /SigmaFactorBS="aaatacatatgggcctcctttttgttaacctaatttaaaatc aTGTTGACAatctttttgttcttTATTACTCTATGATTGTGTAtgtcaacctaagggg g" /listShort="bioYB" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-10 complement(3159846..3159860) /Source="Nicolas_upshift_promotors" /id="U2499" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.724275724275724" /psig="0.203796203796204" /xcortree=588 /SigmaFactorBS="gccaatcagcgccatatctcccgcacgaagtttacgttgtTT CATcgttgttCCCCCTTAGGTTGACatacacaatcatagagtaataaagaacaaaaag a" /listShort="S1231, yuiH" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3159852) /Source="Nicolas_upshifts" /id="U2499" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.724275724275724" /psig="0.203796203796204" /xcortree=588 /SigmaFactorBS="gccaatcagcgccatatctcccgcacgaagtttacgttgtTT CATcgttgttCCCCCTTAGGTTGACatacacaatcatagagtaataaagaacaaaaag a" /listShort="S1231, yuiH" /GFF_Attribute="listLong" promotor_-35 complement(3159868..3159872) /Source="Nicolas_upshift_promotors" /id="U2499" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.724275724275724" /psig="0.203796203796204" /xcortree=588 /SigmaFactorBS="gccaatcagcgccatatctcccgcacgaagtttacgttgtTT CATcgttgttCCCCCTTAGGTTGACatacacaatcatagagtaataaagaacaaaaag a" /listShort="S1231, yuiH" /GFF_Attribute="listLong" /label="promotor_-35" CDS 3159868..3160470 /gene="bioYB" /locus_tag="BSU_32030" /old_locus_tag="BSU32030" /function="16.1: Circulate" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 11717296, 15849754, 16850406, 24816803; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative biotin transporter" /protein_id="NP_391083.1" /db_xref="EnsemblGenomes-Gn:BSU32030" /db_xref="EnsemblGenomes-Tr:CAB15193" /db_xref="GOA:O32104" /db_xref="InterPro:IPR003784" /db_xref="SubtiList:BG13972" /db_xref="UniProtKB/Swiss-Prot:O32104" /translation="MKQRKLRAGDMALIGMFAALMAVGANITSVAPFLQVAGIPLSMQ PFFCLLAALLLGSKRAAIAMIVYALVGLAGAPVFAQFSAGFAPFAGKSGGFIISYIPA AFAAGWFLERNIQPSKIRFLIASLIGTAIMYLIGTTYMYLALKLWIHTPVSYGTAWGF MIWFMVKDTALAVILSFIAPAIYRSIHKATGFNRNHISST*" gene 3159868..3160470 /gene="bioYB" /locus_tag="BSU_32030" /old_locus_tag="BSU32030" downshifts 3160456 /Source="Nicolas_upshifts" /id="D1654" /incds=0 /nref=145 /ntot=206 /MaxReadThrough="3.24182" /MaxDrop="6.72885" /score="12.6395055" /energy="-6.3" /TU="U2498" /idTUdmin="U2498" /TUdmin="-24" /isTUend="FALSE" CDS complement(3160540..3161868) /gene="hisP" /locus_tag="BSU_32040" /old_locus_tag="BSU32040" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2b: Function from indirect experimental evidences (e.g. phenotypes); PubMedId: 15135544, 15849754, 16850406, 23504016; Product type t : transporter" /codon_start=1 /transl_table=11 /product="histidine / basic amino acid transporter" /protein_id="NP_391084.1" /db_xref="EnsemblGenomes-Gn:BSU32040" /db_xref="EnsemblGenomes-Tr:CAB15194" /db_xref="GOA:O32105" /db_xref="InterPro:IPR018461" /db_xref="InterPro:IPR032813" /db_xref="SubtiList:BG13971" /db_xref="UniProtKB/Swiss-Prot:O32105" /translation="MNAVVIAVLLMLVLSLLRVNIVIALIIGALAGGLTGGLGLGETV KAFTDGLGGNATVAVSYAMLGAFAAALTKTGLPDAMVEASVKLIGNKEDSRKKALSKV LIVLIILIVSCFSQNVVPVHIAFIPVLIPPLLKIFNELEMDRRLIACVITFGLTAPYI LLPVGFGQIFQGMLKDNMADAGLNVPLADIPYALIIPVAGMVVGLILSVIVYRKPKQY ETKDISGAEASPYTRKSIGIAVLAIVVSLGVQLYLSQTLGVEGMIMGALAGLIVLFVS GVMKRDEADSLITDGMVLMAFIGFVMLVAAGFSNVLTKTGDVESLVKTSAGFIGHSQS LGALLMLIVGLLITMGIGSSFATIPVITTIFVPLCMQLGFSPMATIAIIGAAAALGDA GSPASDSTLGPTSGLSADGQHHHIWDTCVPTFIFYNIPLVIFGWIAALVL*" gene complement(3160540..3161868) /gene="hisP" /locus_tag="BSU_32040" /old_locus_tag="BSU32040" downshifts complement(3160556) /Source="Nicolas_upshifts" /id="D1655" /incds=0 /nref=14 /ntot=114 /MaxReadThrough="4.26298" /MaxDrop="4.37949" /score="18.6861113" /energy="-15.4" /TU="U2500" /idTUdmin="U2500" /TUdmin="-66" /isTUend="FALSE" promotor_-10 complement(3161922..3161941) /Source="Nicolas_upshift_promotors" /id="U2500" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.55044955044955" /psig=1 /xcortree=2776 /SigmaFactorBS="ggattttttcttccgaaatcttTAGTTGACtaaagtggatcg gtTATGATACGATACGTTCGTActttatttatctactacattagcaaactaaaggatt t" /listShort="yuiF" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3161925) /Source="Nicolas_upshifts" /id="U2500" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.55044955044955" /psig=1 /xcortree=2776 /SigmaFactorBS="ggattttttcttccgaaatcttTAGTTGACtaaagtggatcg gtTATGATACGATACGTTCGTActttatttatctactacattagcaaactaaaggatt t" /listShort="yuiF" /GFF_Attribute="listLong" promotor_-35 complement(3161956..3161963) /Source="Nicolas_upshift_promotors" /id="U2500" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.55044955044955" /psig=1 /xcortree=2776 /SigmaFactorBS="ggattttttcttccgaaatcttTAGTTGACtaaagtggatcg gtTATGATACGATACGTTCGTActttatttatctactacattagcaaactaaaggatt t" /listShort="yuiF" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3162015..3163517) /gene="pepA" /locus_tag="BSU_32050" /old_locus_tag="BSU32050" /EC_number="3.4.11.1" /function="16.11: Scavenge (Catabolism)" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 8057849, 9864319, 10449417, 26936797; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="cytosol aminopeptidase" /protein_id="NP_391085.1" /db_xref="EnsemblGenomes-Gn:BSU32050" /db_xref="EnsemblGenomes-Tr:CAB15195" /db_xref="GOA:O32106" /db_xref="InterPro:IPR000819" /db_xref="InterPro:IPR008283" /db_xref="InterPro:IPR011356" /db_xref="InterPro:IPR023042" /db_xref="SubtiList:BG13970" /db_xref="UniProtKB/Swiss-Prot:O32106" /translation="MFYAVQQSEHTETLVVGLFQKSQLTGKALEIDEMLEGHLTQLLK EGDVSAKPNQVSKVFPPSSAGMKRIYFVGLGREANYSFEQAKERFAHVFQAIHKDRKQ ETAVLLDTFISEDVPPADAAHALAESCLLASYEVQDYKHKSNEPDKQIEAVYVVTDED TQEVQAGLRVGQAYGQGTNSARTLVNMPGNMLTATDLASYAEELAAKYDFECEILEKS EMEELGMGGILAVNQGSTEPPKMIVLKYQGKKEWEDVVGLVGKGITFDTGGYSIKTKS GIVGMKSDMGGAAAVLGAMETIGELRPEQNVLCVIPSTDNMISGGAMKPDDVIVSLSG KTIEILNTDAEGRLVLADGITYAKQHGASVLVDVATLTGGVVVALGTETTGAMTNDQS FYQQVADAAQECGEAIWQLPITEKDKKRVKSSQMADLSNSPGREGHAIMAGTFLGEFA ESTPWVHLDIAGTATANKATCFGPAGATGVMARTLATLAERFTLEEDKNE*" gene complement(3162015..3163517) /gene="pepA" /locus_tag="BSU_32050" /old_locus_tag="BSU32050" downshifts complement(3162030) /Source="Nicolas_upshifts" /id="D1656" /incds=0 /nref=149 /ntot=220 /MaxReadThrough="4.44151" /MaxDrop="5.59726" /score="31.6277104" /energy="-16" /TU="NA" /idTUdmin="U2503" /TUdmin=0 /isTUend="TRUE" misc_feature 3163082..3163096 /Source="Nicolas_upshift_promotors" /id="U2501" /multdbtbs="-" /comp="M19" /sig="Sig-" /pcomp="0.345654345654346" /psig="0.420579420579421" /xcortree=308 /SigmaFactorBS="atcttcatctgttacaacatacacggcttcaatttgtttgtc agGCTCATTTGATTTATgcttataatcctgcacctcataggaagcaagcaggcagctc t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 3163098 /Source="Nicolas_upshifts" /id="U2501" /multdbtbs="-" /comp="M19" /sig="Sig-" /pcomp="0.345654345654346" /psig="0.420579420579421" /xcortree=308 /SigmaFactorBS="atcttcatctgttacaacatacacggcttcaatttgtttgtc agGCTCATTTGATTTATgcttataatcctgcacctcataggaagcaagcaggcagctc t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" S_feature complement(3163518..3163592) /Source="Nicolas_S_feature" /locus_tag="new_3297920_3297994_c" /HighExp="M40t90, Lbtran, LBGtran, Lbstat, C90, M0t90, T1.0H, LoTm, M40t45, BI" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S1232" promotor_-35 3163540..3163547 /Source="Nicolas_upshift_promotors" /id="U2502" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.927072927072927" /psig="0.997002997002997" /xcortree=617 /SigmaFactorBS="ttgaaccgcataaaacatgaggcttacactcctaacgtaaTG GGTATTtgtaatgaacAATGGTATAATAGGAAAAACattctttccactatacttattt t" /listShort="S1233, yuiD" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3163558..3163577 /Source="Nicolas_upshift_promotors" /id="U2502" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.927072927072927" /psig="0.997002997002997" /xcortree=617 /SigmaFactorBS="ttgaaccgcataaaacatgaggcttacactcctaacgtaaTG GGTATTtgtaatgaacAATGGTATAATAGGAAAAACattctttccactatacttattt t" /listShort="S1233, yuiD" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 3163560..3163674 /Source="Nicolas_S_feature" /locus_tag="new_3297962_3298076" /HighExp="Etha, Cold, Gly, Sw, LoTm, BC, B60, C90, dia5, Lbtran" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.997" /TUlongSig="NA" /TUlongPSig="NA" /label="S1233" upshifts 3163560 /Source="Nicolas_upshifts" /id="U2502" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.927072927072927" /psig="0.997002997002997" /xcortree=617 /SigmaFactorBS="ttgaaccgcataaaacatgaggcttacactcctaacgtaaTG GGTATTtgtaatgaacAATGGTATAATAGGAAAAACattctttccactatacttattt t" /listShort="S1233, yuiD" /GFF_Attribute="listLong" misc_feature complement(3163587..3163606) /Source="Nicolas_upshift_promotors" /id="U2503" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.601398601398601" /psig="0.999000999001" /xcortree=3139 /SigmaFactorBS="tttgaaaaatccttcgtgtttcaaaagaaaaaagcaagtctt agactgttgTTTGTTAAAATAAGTATAGTggaaagaatgtttttcctattataccatt g" /listShort="S1232, pepA" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(3163597) /Source="Nicolas_upshifts" /id="U2503" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.601398601398601" /psig="0.999000999001" /xcortree=3139 /SigmaFactorBS="tttgaaaaatccttcgtgtttcaaaagaaaaaagcaagtctt agactgttgTTTGTTAAAATAAGTATAGTggaaagaatgtttttcctattataccatt g" /listShort="S1232, pepA" /GFF_Attribute="listLong" CDS 3163675..3164151 /gene="yuiD" /locus_tag="BSU_32060" /old_locus_tag="BSU32060" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative integral inner membrane protein" /protein_id="NP_391086.1" /db_xref="EnsemblGenomes-Gn:BSU32060" /db_xref="EnsemblGenomes-Tr:CAB15196" /db_xref="GOA:O32107" /db_xref="InterPro:IPR003832" /db_xref="SubtiList:BG13969" /db_xref="UniProtKB/Swiss-Prot:O32107" /translation="MELLTNFPLLSSLAAIIFAQVIKVPIQFIVSRKLDWSLVTSTGG MPSSHSAAVTALSTGVALEHGLDSSLFAVSAIFAVITMFDATGVRRHAGEQATVINKL VIDFNRFVNEAKDFPKAAEKEKQKKLKELLGHQPIEVFFGGLTGILLTLVLAYFFM*" gene 3163675..3164151 /gene="yuiD" /locus_tag="BSU_32060" /old_locus_tag="BSU32060" downshifts 3164100 /Source="Nicolas_upshifts" /id="D1657" /incds=0 /nref=18 /ntot=174 /MaxReadThrough="3.22946" /MaxDrop="3.90704" /score="10.9647804" /energy="-11.6" /TU="U2502" /idTUdmin="U2502" /TUdmin="-208" /isTUend="FALSE" CDS complement(3164182..3164838) /gene="spsC" /locus_tag="BSU_32070" /old_locus_tag="BSU32070" /experiment="publication(s) with functional evidences, PMID:26163297" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 26163297; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="stationary phase survival protein" /protein_id="NP_391087.1" /db_xref="EnsemblGenomes-Gn:BSU32070" /db_xref="EnsemblGenomes-Tr:CAB15197" /db_xref="GOA:O32108" /db_xref="InterPro:IPR010611" /db_xref="InterPro:IPR036908" /db_xref="PDB:4WJT" /db_xref="PDB:4WLI" /db_xref="PDB:4WLK" /db_xref="SubtiList:BG13968" /db_xref="UniProtKB/Swiss-Prot:O32108" /translation="MMLNMIRRLLMTCLFLLAFGTTFLSVSGIEAKDLSKWVQEHQEK HLKHAGLRLKALQQKQTQTTSAAEDKTKPLEEAFDWDEYPVQRVTATGYTAGAESTGK NPGDPLYGLTYSGVKVKRDLYSTVAADPSVFPIGTILFIPNYGLGVVADTGSAIKGNR LDLYFETVKDVYNEWGKKTLDVYVIKKGTGKITEDELEKLNETKSLQVFRNQYKTVKE *" gene complement(3164182..3164838) /gene="spsC" /locus_tag="BSU_32070" /old_locus_tag="BSU32070" downshifts complement(3164210) /Source="Nicolas_upshifts" /id="D1658" /incds=0 /nref=178 /ntot=253 /MaxReadThrough="0.714039999999999" /MaxDrop="6.31907" /score="33.0538307" /energy="-12.6" /TU="NA" /idTUdmin="U2505" /TUdmin="-2" /isTUend="TRUE" promotor_-35 3164486..3164495 /Source="Nicolas_upshift_promotors" /id="U2504" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=1331 /SigmaFactorBS="tggaatataaatcccgtttcACTTTCACACctgaatatgtaa gCCCGTATAATGGATCACCGGgatttttgcccgtcgactcagctcctgctgtgtagcc t" /listShort="S1234, S1235, S1236, S1237" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3164509..3164528 /Source="Nicolas_upshift_promotors" /id="U2504" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=1331 /SigmaFactorBS="tggaatataaatcccgtttcACTTTCACACctgaatatgtaa gCCCGTATAATGGATCACCGGgatttttgcccgtcgactcagctcctgctgtgtagcc t" /listShort="S1234, S1235, S1236, S1237" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3164526 /Source="Nicolas_upshifts" /id="U2504" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=1331 /SigmaFactorBS="tggaatataaatcccgtttcACTTTCACACctgaatatgtaa gCCCGTATAATGGATCACCGGgatttttgcccgtcgactcagctcctgctgtgtagcc t" /listShort="S1234, S1235, S1236, S1237" /GFF_Attribute="listLong" S_feature 3164528..3164974 /Source="Nicolas_S_feature" /locus_tag="new_3298930_3299376" /HighExp="S6, S8, S7, BT, B36, G/S, S5, Pyr, Cold, B60" /AntisenseName="yuiC" /AntisenseCor="0.52395204592174105" /AntisenseRegPval="-19.600000000000001" /CDS_PredictionProba="NA" /TUshortSig="SigK" /TUshortPSig="0.998" /TUlongSig="NA" /TUlongPSig="NA" /label="S1234" upshifts complement(3164852) /Source="Nicolas_upshifts" /id="U2505" /multdbtbs="SigF" /comp="M8" /sig="SigGF" /pcomp="0.543456543456543" /psig="0.543456543456543" /xcortree=1022 /SigmaFactorBS="ttatgcgttcagctcattcaccatttTGAATAAtgctctctc cacttGGGAACAATGATtcggaggagaggtgaatgatgttgaatatgatcagacgttt g" /listShort="yuiC" /GFF_Attribute="listLong" promotor_-10 complement(3164854..3164865) /Source="Nicolas_upshift_promotors" /id="U2505" /multdbtbs="SigF" /comp="M8" /sig="SigGF" /pcomp="0.543456543456543" /psig="0.543456543456543" /xcortree=1022 /SigmaFactorBS="ttatgcgttcagctcattcaccatttTGAATAAtgctctctc cacttGGGAACAATGATtcggaggagaggtgaatgatgttgaatatgatcagacgttt g" /listShort="yuiC" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 complement(3164880..3164886) /Source="Nicolas_upshift_promotors" /id="U2505" /multdbtbs="SigF" /comp="M8" /sig="SigGF" /pcomp="0.543456543456543" /psig="0.543456543456543" /xcortree=1022 /SigmaFactorBS="ttatgcgttcagctcattcaccatttTGAATAAtgctctctc cacttGGGAACAATGATtcggaggagaggtgaatgatgttgaatatgatcagacgttt g" /listShort="yuiC" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 3164931 /Source="Nicolas_upshifts" /id="D1659" /incds=0 /nref=3 /ntot=11 /MaxReadThrough="7.61734" /MaxDrop="4.9382" /score="4.8726481" /energy="-7.9" /TU="U2504" /idTUdmin="U2506" /TUdmin="-323" /isTUend="FALSE" CDS complement(3164942..3165262) /gene="yuiB" /locus_tag="BSU_32080" /old_locus_tag="BSU32080" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_391088.1" /db_xref="EnsemblGenomes-Gn:BSU32080" /db_xref="EnsemblGenomes-Tr:CAB15198" /db_xref="GOA:O32109" /db_xref="InterPro:IPR025917" /db_xref="SubtiList:BG13967" /db_xref="UniProtKB/Swiss-Prot:O32109" /translation="MISLPVVIISIVLFFVLFFGIGFLLNMLLRMSWIMAVIYPIVCL FIISKEKLISYVQSPGESFASLFHRVLSLAAADVLILVSGLAGAIVSGIAINMLRKRG YQMF*" gene complement(3164942..3165262) /gene="yuiB" /locus_tag="BSU_32080" /old_locus_tag="BSU32080" downshifts complement(3164956) /Source="Nicolas_upshifts" /id="D1660" /incds=0 /nref=151 /ntot=218 /MaxReadThrough="4.24535" /MaxDrop="5.6597" /score="13.4559443" /energy="-7.6" /TU="U2507,U2508" /idTUdmin="U2510" /TUdmin=660 /isTUend="FALSE" S_feature 3164976..3165186 /Source="Nicolas_S_feature" /locus_tag="new_3299378_3299588" /HighExp="S8, S6, S7, BT, Cold, Gly, H2O2, G/S, C30, G180" /AntisenseName="yuiB" /AntisenseCor="-0.11290507783715401" /AntisenseRegPval="-1.2" /CDS_PredictionProba="NA" /TUshortSig="SigK" /TUshortPSig="0.998" /TUlongSig="NA" /TUlongPSig="NA" /label="S1235" promotor_no_box 3165128..3165228 /Source="Nicolas_upshift_promotors" /id="U2506" /multdbtbs="-" /comp="M21" /sig="Sig-" /pcomp="0.641358641358641" /psig="0.02997002997003" /xcortree=280 /SigmaFactorBS="gaaaaggcatacaattggataaatcacagccataatccaaga cattctcagcagcatgtttaataagaaaccgattccaaaaaacaagacaaaaaacaaa a" /listShort="S1236" /GFF_Attribute="listLong" /label="promotor_no_box" S_feature 3165188..3165297 /Source="Nicolas_S_feature" /locus_tag="new_3299590_3299699" /HighExp="S8, S6, BT, S7, Sw, Gly, G180, BC, Diami, H2O2" /AntisenseName="yuiB" /AntisenseCor="-7.7565560595235006E-2" /AntisenseRegPval="-0.7" /CDS_PredictionProba="NA" /TUshortSig="Sig-, SigK" /TUshortPSig="0.03, 0.998" /TUlongSig="NA" /TUlongPSig="NA" /label="S1236" upshifts 3165188 /Source="Nicolas_upshifts" /id="U2506" /multdbtbs="-" /comp="M21" /sig="Sig-" /pcomp="0.641358641358641" /psig="0.02997002997003" /xcortree=280 /SigmaFactorBS="gaaaaggcatacaattggataaatcacagccataatccaaga cattctcagcagcatgtttaataagaaaccgattccaaaaaacaagacaaaaaacaaa a" /listShort="S1236" /GFF_Attribute="listLong" downshifts 3165254 /Source="Nicolas_upshifts" /id="D1661" /incds=0 /nref=10 /ntot=28 /MaxReadThrough="3.79664" /MaxDrop="6.06021" /score="4.8726481" /energy="-7.9" /TU="U2504" /idTUdmin="U2506" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(3165281..3165300) /Source="Nicolas_upshift_promotors" /id="U2507" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.797202797202797" /psig="0.995004995004995" /xcortree=435 /SigmaFactorBS="aaaagacagtcattctttttccagCCGTTGACtttatttcag ccccCGCGTTACACTAAAAACAACgcaggggggtggaataggttgattagtctgccag t" /listShort="yuiB, yuiC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3165286) /Source="Nicolas_upshifts" /id="U2507" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.797202797202797" /psig="0.995004995004995" /xcortree=435 /SigmaFactorBS="aaaagacagtcattctttttccagCCGTTGACtttatttcag ccccCGCGTTACACTAAAAACAACgcaggggggtggaataggttgattagtctgccag t" /listShort="yuiB, yuiC" /GFF_Attribute="listLong" S_feature 3165299..3165850 /Source="Nicolas_S_feature" /locus_tag="new_3299701_3300252" /HighExp="S6, S8, S7, Cold, H2O2, BC, Sw, Pyr, BT, C30" /AntisenseName="yuiA" /AntisenseCor="5.87811391089679E-2" /AntisenseRegPval="-0.5" /CDS_PredictionProba="NA" /TUshortSig="SigK" /TUshortPSig="0.998" /TUlongSig="NA" /TUlongPSig="NA" /label="S1237" promotor_-35 complement(3165315..3165322) /Source="Nicolas_upshift_promotors" /id="U2507" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.797202797202797" /psig="0.995004995004995" /xcortree=435 /SigmaFactorBS="aaaagacagtcattctttttccagCCGTTGACtttatttcag ccccCGCGTTACACTAAAAACAACgcaggggggtggaataggttgattagtctgccag t" /listShort="yuiB, yuiC" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3165316..3165459) /gene="yuiA" /locus_tag="BSU_32090" /old_locus_tag="BSU32090" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_391089.1" /db_xref="EnsemblGenomes-Gn:BSU32090" /db_xref="EnsemblGenomes-Tr:CAB15199" /db_xref="InterPro:IPR035272" /db_xref="InterPro:IPR036410" /db_xref="SubtiList:BG12389" /db_xref="UniProtKB/Swiss-Prot:O32110" /translation="MKTATTTASHACPFCSGKGYFQLILGGSETCPSCQGTGKDSHSF SSR*" gene complement(3165316..3165459) /gene="yuiA" /locus_tag="BSU_32090" /old_locus_tag="BSU32090" promotor_-10 complement(3165483..3165502) /Source="Nicolas_upshift_promotors" /id="U2508" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.657342657342657" /psig="0.999000999001" /xcortree=2880 /SigmaFactorBS="gtatgtttccgcttacatcaaaagatttgtcacatgatctga cTTTAtTgttgacagcttgaTATGGTATATTATCAGAAAAttaagaaaaagggtgatg a" /listShort="yuiA, yuiB, yuiC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3165504) /Source="Nicolas_upshifts" /id="U2508" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.657342657342657" /psig="0.999000999001" /xcortree=2880 /SigmaFactorBS="gtatgtttccgcttacatcaaaagatttgtcacatgatctga cTTTAtTgttgacagcttgaTATGGTATATTATCAGAAAAttaagaaaaagggtgatg a" /listShort="yuiA, yuiB, yuiC" /GFF_Attribute="listLong" promotor_-35 complement(3165518..3165521) /Source="Nicolas_upshift_promotors" /id="U2508" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.657342657342657" /psig="0.999000999001" /xcortree=2880 /SigmaFactorBS="gtatgtttccgcttacatcaaaagatttgtcacatgatctga cTTTAtTgttgacagcttgaTATGGTATATTATCAGAAAAttaagaaaaagggtgatg a" /listShort="yuiA, yuiB, yuiC" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3165632..3166852) /gene="yumB" /locus_tag="BSU_32100" /old_locus_tag="BSU32100" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15937154, 17015645, 26098117; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative NAD-disulfide oxidoreductase" /protein_id="NP_391090.1" /db_xref="EnsemblGenomes-Gn:BSU32100" /db_xref="EnsemblGenomes-Tr:CAB15200" /db_xref="GOA:O05267" /db_xref="InterPro:IPR023753" /db_xref="InterPro:IPR036188" /db_xref="SubtiList:BG12390" /db_xref="UniProtKB/Swiss-Prot:O05267" /translation="MALNKPKIVILGAGYGGLMTVTRLTKYVGPNDADITLVNKHNYH YETTWMHEASAGTLHHDRCRYQIKDVINQSRVNFVQDTVKAIKIDEKKVVLANGELQY DYLVIGLGAVPETFGIKGLKEYAFPIANINTSRLLREHIELQFATYNTEAEKRPDRLT IVVGGAGFTGIEFLGELAARVPELCKEYDVDRSLVRIICVEAAPTVLPGFDPELVDYA VHYLEENGVEFKIGTAVQECTPEGVRVGKKDEEPEQIKSQTVVWAAGVRGHPIVEEAG FENMRGRVKVNPDLRAPGHDNVFILGDSSLFMNEDTERPYPPTAQIAMQQGITVAKNL GRLIKGGELEEFKPDIKGTVASLGEHNAVGVVYGRKLKGTPASFMKKVIDNRSLFMIG GLGLTLKKGKFKFF*" gene complement(3165632..3166852) /gene="yumB" /locus_tag="BSU_32100" /old_locus_tag="BSU32100" downshifts complement(3165660) /Source="Nicolas_upshifts" /id="D1662" /incds=0 /nref=15 /ntot=123 /MaxReadThrough="3.19525" /MaxDrop="3.6794" /score="23.523765" /energy="-8.9" /TU="U2510" /idTUdmin="U2509" /TUdmin=0 /isTUend="TRUE" S_feature complement(3166853..3166980) /Source="Nicolas_S_feature" /locus_tag="new_3301255_3301382_c" /HighExp="Salt, S4, Etha, S5, S3, S7, S6, LoTm, B36, S8" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigEF, SigA" /TUshortPSig="0.752, 0.993" /TUlongSig="NA" /TUlongPSig="NA" /label="S1238" upshifts complement(3166980) /Source="Nicolas_upshifts" /id="U2509" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.752247752247752" /psig="0.752247752247752" /xcortree=1120 /SigmaFactorBS="aaatgaaatgatctttttcTGAATGtttcttgggccagccGG ATAAACATGATAATAGTgctacgggtaaggacttcacaaaaaacttttcaatatattt c" /listShort="S1238, yumB" /GFF_Attribute="listLong" S_feature complement(3166982..3167046) /Source="Nicolas_S_feature" /locus_tag="new_3301384_3301448_c" /HighExp="Salt, Etha, Heat, BMM, BC, H2O2, Paraq, C30, Sw, Oxctl" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.993" /TUlongSig="NA" /TUlongPSig="NA" /label="S1239" promotor_-10 complement(3166982..3167000) /Source="Nicolas_upshift_promotors" /id="U2509" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.752247752247752" /psig="0.752247752247752" /xcortree=1120 /SigmaFactorBS="aaatgaaatgatctttttcTGAATGtttcttgggccagccGG ATAAACATGATAATAGTgctacgggtaaggacttcacaaaaaacttttcaatatattt c" /listShort="S1238, yumB" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 complement(3167016..3167021) /Source="Nicolas_upshift_promotors" /id="U2509" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.752247752247752" /psig="0.752247752247752" /xcortree=1120 /SigmaFactorBS="aaatgaaatgatctttttcTGAATGtttcttgggccagccGG ATAAACATGATAATAGTgctacgggtaaggacttcacaaaaaacttttcaatatattt c" /listShort="S1238, yumB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(3167037..3167056) /Source="Nicolas_upshift_promotors" /id="U2510" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.460539460539461" /psig="0.993006993006993" /xcortree=671 /SigmaFactorBS="tcgtaaggatctaacgtgcccatccgtTCTTGAAAatatttc cgcaggcCGCTACGATAATAACCAAATgaaatgatctttttctgaatgtttcttgggc c" /listShort="S1239, S1238, yumB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3167045) /Source="Nicolas_upshifts" /id="U2510" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.460539460539461" /psig="0.993006993006993" /xcortree=671 /SigmaFactorBS="tcgtaaggatctaacgtgcccatccgtTCTTGAAAatatttc cgcaggcCGCTACGATAATAACCAAATgaaatgatctttttctgaatgtttcttgggc c" /listShort="S1239, S1238, yumB" /GFF_Attribute="listLong" promotor_-35 complement(3167071..3167078) /Source="Nicolas_upshift_promotors" /id="U2510" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.460539460539461" /psig="0.993006993006993" /xcortree=671 /SigmaFactorBS="tcgtaaggatctaacgtgcccatccgtTCTTGAAAatatttc cgcaggcCGCTACGATAATAACCAAATgaaatgatctttttctgaatgtttcttgggc c" /listShort="S1239, S1238, yumB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 3167120..3167127 /Source="Nicolas_upshift_promotors" /id="U2511" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.847152847152847" /psig=1 /xcortree=2382 /SigmaFactorBS="acggatgggcacgttagatccttacgattttttctgctgacT CGTCAATttgaacggcaaTATGGTATAATTAATAACAAttttcatttaggaggcaatt t" /listShort="yumC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3167139..3167158 /Source="Nicolas_upshift_promotors" /id="U2511" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.847152847152847" /psig=1 /xcortree=2382 /SigmaFactorBS="acggatgggcacgttagatccttacgattttttctgctgacT CGTCAATttgaacggcaaTATGGTATAATTAATAACAAttttcatttaggaggcaatt t" /listShort="yumC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3167139 /Source="Nicolas_upshifts" /id="U2511" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.847152847152847" /psig=1 /xcortree=2382 /SigmaFactorBS="acggatgggcacgttagatccttacgattttttctgctgacT CGTCAATttgaacggcaaTATGGTATAATTAATAACAAttttcatttaggaggcaatt t" /listShort="yumC" /GFF_Attribute="listLong" CDS 3167184..3168182 /gene="trxBB" /locus_tag="BSU_32110" /old_locus_tag="BSU32110" /EC_number="1.18.1.2" /function="16.2: Construct biomass (Anabolism)" /function="16.7: Manage energy" /function="16.10: Respire" /experiment="publication(s) with functional evidences, PMID:15252706, 22938038, 26507228, 26965753" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15252706, 22938038, 26507228, 26965753; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="ferredoxin-NADP+ reductase (flavodoxin)" /protein_id="NP_391091.2" /db_xref="EnsemblGenomes-Gn:BSU32110" /db_xref="EnsemblGenomes-Tr:CAB15201" /db_xref="GOA:O05268" /db_xref="InterPro:IPR000103" /db_xref="InterPro:IPR022890" /db_xref="InterPro:IPR023753" /db_xref="InterPro:IPR036188" /db_xref="PDB:3LZW" /db_xref="PDB:3LZX" /db_xref="SubtiList:BG12391" /db_xref="UniProtKB/Swiss-Prot:O05268" /translation="MREDTKVYDITIIGGGPVGLFTAFYGGMRQASVKIIESLPQLGG QLSALYPEKYIYDVAGFPKIRAQELINNLKEQMAKFDQTICLEQAVESVEKQADGVFK LVTNEETHYSKTVIITAGNGAFKPRKLELENAEQYEGKNLHYFVDDLQKFAGRRVAIL GGGDSAVDWALMLEPIAKEVSIIHRRDKFRAHEHSVENLHASKVNVLTPFVPAELIGE DKIEQLVLEEVKGDRKEILEIDDLIVNYGFVSSLGPIKNWGLDIEKNSIVVKSTMETN IEGFFAAGDICTYEGKVNLIASGFGEAPTAVNNAKAYMDPKARVQPLHSTSLFENK*" gene 3167184..3168182 /gene="trxBB" /locus_tag="BSU_32110" /old_locus_tag="BSU32110" promotor_-10 complement(3167207..3167225) /Source="Nicolas_upshift_promotors" /id="U2512" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.99000999000999" /psig="0.99000999000999" /xcortree=1201 /SigmaFactorBS="gacgcttgcctgtctcatcccgccgtaaaaagcggTGAATAa gccgaccggtcccccGCCTATAATTGTAATATCAtaaacctttgtatcctctcgcata c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3167222) /Source="Nicolas_upshifts" /id="U2512" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.99000999000999" /psig="0.99000999000999" /xcortree=1201 /SigmaFactorBS="gacgcttgcctgtctcatcccgccgtaaaaagcggTGAATAa gccgaccggtcccccGCCTATAATTGTAATATCAtaaacctttgtatcctctcgcata c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(3167242..3167247) /Source="Nicolas_upshift_promotors" /id="U2512" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.99000999000999" /psig="0.99000999000999" /xcortree=1201 /SigmaFactorBS="gacgcttgcctgtctcatcccgccgtaaaaagcggTGAATAa gccgaccggtcccccGCCTATAATTGTAATATCAtaaacctttgtatcctctcgcata c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 3168158 /Source="Nicolas_upshifts" /id="D1663" /incds=0 /nref=162 /ntot=262 /MaxReadThrough="0.70088" /MaxDrop="7.47867" /score="21.6819221" /energy="-12.8" /TU="U2511" /idTUdmin="U2511" /TUdmin="-22" /isTUend="TRUE" CDS complement(3168221..3168361) /gene="yuzG" /locus_tag="BSU_32120" /old_locus_tag="BSU32120" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein or unknown function" /protein_id="NP_391092.1" /db_xref="EnsemblGenomes-Gn:BSU32120" /db_xref="EnsemblGenomes-Tr:CAB15202" /db_xref="GOA:O32111" /db_xref="SubtiList:BG14056" /db_xref="UniProtKB/Swiss-Prot:O32111" /translation="MAQNEEKTPKSQKIQDRIIMAMIWVVAALVIALVVGTALNYINI FK*" gene complement(3168221..3168361) /gene="yuzG" /locus_tag="BSU_32120" /old_locus_tag="BSU32120" downshifts complement(3168233) /Source="Nicolas_upshifts" /id="D1664" /incds=0 /nref=61 /ntot=234 /MaxReadThrough="1.27572" /MaxDrop="5.65243" /score="32.0354025" /energy="-12.8" /TU="NA" /idTUdmin="U2515" /TUdmin=1 /isTUend="TRUE" S_feature complement(3168362..3168491) /Source="Nicolas_S_feature" /locus_tag="new_3302764_3302893_c" /HighExp="dia15, Salt, Cold, Diami, H2O2, Etha, GM 15, dia5, MG-0.2, MG t5" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.36371900000000001" /TUshortSig="SigA, SigGF" /TUshortPSig="0.999, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S1240" promotor_-10 complement(3168472..3168491) /Source="Nicolas_upshift_promotors" /id="U2513" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.344655344655345" /psig="0.999000999001" /xcortree=1851 /SigmaFactorBS="aacattatgatttgctggcaggtgtggtgcaagtgccgaaGC TTGTCatgcagggtgagtTTAGGTATCATAGTTTTAACgaatggtcttagagagcgga t" /listShort="S1240, yuzG" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3168491) /Source="Nicolas_upshifts" /id="U2513" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.344655344655345" /psig="0.999000999001" /xcortree=1851 /SigmaFactorBS="aacattatgatttgctggcaggtgtggtgcaagtgccgaaGC TTGTCatgcagggtgagtTTAGGTATCATAGTTTTAACgaatggtcttagagagcgga t" /listShort="S1240, yuzG" /GFF_Attribute="listLong" S_feature complement(3168493..3168740) /Source="Nicolas_S_feature" /locus_tag="new_3302895_3303142_c" /HighExp="S8, S5, S6, S7, S4, ferm, nit, C30, Pyr, T5.0H" /AntisenseName="guaC" /AntisenseCor="-0.291283195124732" /AntisenseRegPval="-5.9" /CDS_PredictionProba="NA" /TUshortSig="SigGF" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1241" promotor_-35 complement(3168505..3168511) /Source="Nicolas_upshift_promotors" /id="U2513" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.344655344655345" /psig="0.999000999001" /xcortree=1851 /SigmaFactorBS="aacattatgatttgctggcaggtgtggtgcaagtgccgaaGC TTGTCatgcagggtgagtTTAGGTATCATAGTTTTAACgaatggtcttagagagcgga t" /listShort="S1240, yuzG" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 3168548..3168555 /Source="Nicolas_upshift_promotors" /id="U2514" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.518481518481518" /psig="0.998001998001998" /xcortree=2630 /SigmaFactorBS="cacttgcaccacacctgccagcaaatcataaTGTTTGACatc ctaaataaaaCAGAGTACATTATATAAGGCgaacatttcatatattatacttttaaat a" /listShort="guaC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3168569..3168588 /Source="Nicolas_upshift_promotors" /id="U2514" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.518481518481518" /psig="0.998001998001998" /xcortree=2630 /SigmaFactorBS="cacttgcaccacacctgccagcaaatcataaTGTTTGACatc ctaaataaaaCAGAGTACATTATATAAGGCgaacatttcatatattatacttttaaat a" /listShort="guaC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3168577 /Source="Nicolas_upshifts" /id="U2514" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.518481518481518" /psig="0.998001998001998" /xcortree=2630 /SigmaFactorBS="cacttgcaccacacctgccagcaaatcataaTGTTTGACatc ctaaataaaaCAGAGTACATTATATAAGGCgaacatttcatatattatacttttaaat a" /listShort="guaC" /GFF_Attribute="listLong" CDS 3168640..3169620 /gene="guaC" /locus_tag="BSU_32130" /old_locus_tag="BSU32130" /EC_number="1.7.1.7" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:6408059, 11591660, 6408059" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 6408059, 11591660, 6408059; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="GMP reductase (NADP-dependent)" /protein_id="NP_391093.2" /db_xref="EnsemblGenomes-Gn:BSU32130" /db_xref="EnsemblGenomes-Tr:CAB15203" /db_xref="GOA:O05269" /db_xref="InterPro:IPR001093" /db_xref="InterPro:IPR005994" /db_xref="InterPro:IPR013785" /db_xref="InterPro:IPR015875" /db_xref="SubtiList:BG12392" /db_xref="UniProtKB/Swiss-Prot:O05269" /translation="MENVFDYEDIQLIPAKCIVNSRSECDTSVRLGGHTFKLPVVPAN MQTIIDEKLAISLAENGYFYVMHRFEPETRIDFIKDMNARGLFSSISVGVKDEEYEFV RQLAEENLTPEYVTIDIAHGHSNAVIEMIQHLKKHLPDSFVIAGNVGTPEAVRELENA GADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAKAASKPIIADGGIRTHGDIAK SIRFGATMVMIGSLFAGHEESPGQTIEKDGKLYKEYFGSASEFQKGEKKNVEGKKMHV AHKGSIKDTLIEMEQDLQSSISYAGGTKLNAIRNVDYVIVKNSIFNGDKY*" gene 3168640..3169620 /gene="guaC" /locus_tag="BSU_32130" /old_locus_tag="BSU32130" upshifts complement(3168741) /Source="Nicolas_upshifts" /id="U2515" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=853 /SigmaFactorBS="cgctagtttttcatctataatcgtcTGCATATtggcagggac gacGGGCAATTTAAAtgtatgtccgcctaaacgtacggatgtatcacattctgaacgg c" /listShort="S1241, S1240, yuzG" /GFF_Attribute="listLong" promotor_-10 complement(3168745..3168756) /Source="Nicolas_upshift_promotors" /id="U2515" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=853 /SigmaFactorBS="cgctagtttttcatctataatcgtcTGCATATtggcagggac gacGGGCAATTTAAAtgtatgtccgcctaaacgtacggatgtatcacattctgaacgg c" /listShort="S1241, S1240, yuzG" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 complement(3168770..3168776) /Source="Nicolas_upshift_promotors" /id="U2515" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=853 /SigmaFactorBS="cgctagtttttcatctataatcgtcTGCATATtggcagggac gacGGGCAATTTAAAtgtatgtccgcctaaacgtacggatgtatcacattctgaacgg c" /listShort="S1241, S1240, yuzG" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 3169588 /Source="Nicolas_upshifts" /id="D1665" /incds=0 /nref=91 /ntot=186 /MaxReadThrough="1.24882" /MaxDrop="7.43286" /score="-2.82053244" /energy="-16.2" /TU="NA" /idTUdmin="U2514" /TUdmin=0 /isTUend="TRUE" downshifts complement(3169693) /Source="Nicolas_upshifts" /id="D1666" /incds=0 /nref=24 /ntot=212 /MaxReadThrough="1.15696" /MaxDrop="6.12198" /score="23.834956" /energy="-16.2" /TU="NA" /idTUdmin="U2517" /TUdmin="-7" /isTUend="TRUE" CDS complement(3169694..3170317) /gene="paiB" /locus_tag="BSU_32140" /old_locus_tag="BSU32140" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1c: Function from experimental evidences in the studied genus; PubMedId: 16210326, 21633969; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="transcriptional regulator (regulates paiA expression)" /protein_id="NP_391094.2" /db_xref="EnsemblGenomes-Gn:BSU32140" /db_xref="EnsemblGenomes-Tr:CAB15204" /db_xref="GOA:P21341" /db_xref="InterPro:IPR007396" /db_xref="InterPro:IPR012349" /db_xref="SubtiList:BG10696" /db_xref="UniProtKB/Swiss-Prot:P21341" /translation="MYIPKYFKVTNAEEIWNFVQENSFGTVVTTEQGKPIATHLPLGF NKKDDHYYITGHFAYGNPQWRTFEACEDVLVMFQGPHAYISSSWYSRENVPTWNYQAV HMYGKASMLEKDELAEELTIMLEKYEKHRDNPVLWDKLSPKLLESELKGIVGFKIKVE DIQAAYKLSQNRNETDYMNVIEQLQNEENPNAKQMAELMEDKLKKQI*" gene complement(3169694..3170317) /gene="paiB" /locus_tag="BSU_32140" /old_locus_tag="BSU32140" CDS complement(3170341..3170859) /gene="paiA" /locus_tag="BSU_32150" /old_locus_tag="BSU32150" /EC_number="2.3.1.57" /function="16.6: Maintain" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:16210326, 17588214, 21633970, 26818562, 28546427" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16210326, 17588214, 21633970, 26818562, 28546427; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="polyamine N-acetyltransferase" /protein_id="NP_391095.1" /db_xref="EnsemblGenomes-Gn:BSU32150" /db_xref="EnsemblGenomes-Tr:CAB15205" /db_xref="GOA:P21340" /db_xref="InterPro:IPR000182" /db_xref="InterPro:IPR016181" /db_xref="PDB:1TIQ" /db_xref="SubtiList:BG10695" /db_xref="UniProtKB/Swiss-Prot:P21340" /translation="MSVKMKKCSREDLQTLQQLSIETFNDTFKEQNSPENMKAYLESA FNTEQLEKELSNMSSQFFFIYFDHEIAGYVKVNIDDAQSEEMGAESLEIERIYIKNSF QKHGLGKHLLNKAIEIALERNKKNIWLGVWEKNENAIAFYKKMGFVQTGAHSFYMGDE EQTDLIMAKTLI*" gene complement(3170341..3170859) /gene="paiA" /locus_tag="BSU_32150" /old_locus_tag="BSU32150" misc_feature complement(3170906..3170925) /Source="Nicolas_upshift_promotors" /id="U2516" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.719280719280719" /psig="0.937062937062937" /xcortree=2765 /SigmaFactorBS="ggagttggtgatgaagaagatttttggaatggtaacaaggtc agtatgtgttcCGTGTTTAAATATATAAAAGggacacaagacaattgaattttaaata a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(3170918) /Source="Nicolas_upshifts" /id="U2516" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.719280719280719" /psig="0.937062937062937" /xcortree=2765 /SigmaFactorBS="ggagttggtgatgaagaagatttttggaatggtaacaaggtc agtatgtgttcCGTGTTTAAATATATAAAAGggacacaagacaattgaattttaaata a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" S_feature complement(3170920..3171028) /Source="Nicolas_S_feature" /locus_tag="new_3305322_3305430_c" /HighExp="LoTm, HiTm, G135, Salt, G180, Cold, LBGstat, T0.0H, B36, T-2.40H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1242" promotor_-10 complement(3171015..3171032) /Source="Nicolas_upshift_promotors" /id="U2517" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.698301698301698" /psig=1 /xcortree=1782 /SigmaFactorBS="gcaagagaaacgctgctttgttgtttgattttTGTTGTAAat acagcaaagttaCGATATATTTAATGCGGAgtatattttattgcatttacaacaaaat c" /listShort="S1242, paiA, paiB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3171026) /Source="Nicolas_upshifts" /id="U2517" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.698301698301698" /psig=1 /xcortree=1782 /SigmaFactorBS="gcaagagaaacgctgctttgttgtttgattttTGTTGTAAat acagcaaagttaCGATATATTTAATGCGGAgtatattttattgcatttacaacaaaat c" /listShort="S1242, paiA, paiB" /GFF_Attribute="listLong" promotor_-35 complement(3171047..3171054) /Source="Nicolas_upshift_promotors" /id="U2517" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.698301698301698" /psig=1 /xcortree=1782 /SigmaFactorBS="gcaagagaaacgctgctttgttgtttgattttTGTTGTAAat acagcaaagttaCGATATATTTAATGCGGAgtatattttattgcatttacaacaaaat c" /listShort="S1242, paiA, paiB" /GFF_Attribute="listLong" /label="promotor_-35" downshifts complement(3171182) /Source="Nicolas_upshifts" /id="D1667" /incds=0 /nref=267 /ntot=269 /MaxReadThrough="1.56881" /MaxDrop="8.24828" /score="12.6937405" /energy="-18.7" /TU="NA" /idTUdmin="U2518" /TUdmin=0 /isTUend="TRUE" CDS complement(3171197..3171559) /gene="sufA" /locus_tag="BSU_32160" /old_locus_tag="BSU32160" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 17698959, 19478995, 20097860, 25447545; Product type c: carrier" /codon_start=1 /transl_table=11 /product="sulfur carrier chaperone involved in Fe-S cluster assembly" /protein_id="NP_391096.1" /db_xref="EnsemblGenomes-Gn:BSU32160" /db_xref="EnsemblGenomes-Tr:CAB15206" /db_xref="GOA:O32113" /db_xref="InterPro:IPR000361" /db_xref="InterPro:IPR016092" /db_xref="InterPro:IPR017870" /db_xref="InterPro:IPR035903" /db_xref="SubtiList:BG14049" /db_xref="UniProtKB/Swiss-Prot:O32113" /translation="MSNPVTITEAAALHIKDMMKEHEEENAFLRVGVKGGGCSGLSYG MGFEHEKSESDSVFDQHGITVLVDKESLDIMNGTVIDYKQSMLGGGFTIDNPNAIASC GCGSSFRTATNAGKPEEC*" gene complement(3171197..3171559) /gene="sufA" /locus_tag="BSU_32160" /old_locus_tag="BSU32160" promotor_-10 complement(3171590..3171609) /Source="Nicolas_upshift_promotors" /id="U2518" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.765234765234765" /psig=1 /xcortree=2038 /SigmaFactorBS="gtgagggtgtctatttcttgtaaaacacctTGTTTGAGaatt ggaacgatcATGTTTATAATAAAAGACAGcaaccggtttttaaaaggaggttcataat g" /listShort="yutM" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3171600) /Source="Nicolas_upshifts" /id="U2518" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.765234765234765" /psig=1 /xcortree=2038 /SigmaFactorBS="gtgagggtgtctatttcttgtaaaacacctTGTTTGAGaatt ggaacgatcATGTTTATAATAAAAGACAGcaaccggtttttaaaaggaggttcataat g" /listShort="yutM" /GFF_Attribute="listLong" promotor_-35 complement(3171623..3171630) /Source="Nicolas_upshift_promotors" /id="U2518" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.765234765234765" /psig=1 /xcortree=2038 /SigmaFactorBS="gtgagggtgtctatttcttgtaaaacacctTGTTTGAGaatt ggaacgatcATGTTTATAATAAAAGACAGcaaccggtttttaaaaggaggttcataat g" /listShort="yutM" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3171638..3172492) /gene="dapF" /locus_tag="BSU_32170" /old_locus_tag="BSU32170" /EC_number="5.1.1.7" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1c: Function from experimental evidences in the studied genus; PubMedId: 14627808, 16723397, 19307721, 28873470; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="diaminopimelate epimerase" /protein_id="NP_391097.1" /db_xref="EnsemblGenomes-Gn:BSU32170" /db_xref="EnsemblGenomes-Tr:CAB15207" /db_xref="GOA:O32114" /db_xref="InterPro:IPR001653" /db_xref="InterPro:IPR018510" /db_xref="SubtiList:BG14048" /db_xref="UniProtKB/Swiss-Prot:O32114" /translation="MNSFRFTKMHGLGNSYIYVNQFEEQLPEEKLSEIAIQVSSVYTG IGSDGMILICPSDQAPVKMRIFNNDGSEGKNCGNGLRCVAKYAYEHKLVEETSFLIET LSGLVKAEVQVENGKVNVVTVDMGEPRLTKSELPMLDGGEEHTINETMAFGEVELTGT AVSMGNPHIVFPIADIEQAPLTTLGPVIEKDPRFPEGINVEFVETVNEQELHFRVWER GSGITQACGTGACAAAVASVLNGVSKRNQDITVHLAGGDLVINWKDNGHVMMTGPAET VCEGVYFL*" gene complement(3171638..3172492) /gene="dapF" /locus_tag="BSU_32170" /old_locus_tag="BSU32170" promotor_-10 complement(3172208..3172227) /Source="Nicolas_upshift_promotors" /id="U2519" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1232 /SigmaFactorBS="gggaaaaactgcggcaacggcctgcgcTGCGTCGCAAaatac gcatatgAGCATAAGCTGGTTGAGGAAacatcttttctgattgaaactctctccgggc t" /listShort="yutM" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3172216) /Source="Nicolas_upshifts" /id="U2519" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1232 /SigmaFactorBS="gggaaaaactgcggcaacggcctgcgcTGCGTCGCAAaatac gcatatgAGCATAAGCTGGTTGAGGAAacatcttttctgattgaaactctctccgggc t" /listShort="yutM" /GFF_Attribute="listLong" promotor_-35 complement(3172240..3172249) /Source="Nicolas_upshift_promotors" /id="U2519" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1232 /SigmaFactorBS="gggaaaaactgcggcaacggcctgcgcTGCGTCGCAAaatac gcatatgAGCATAAGCTGGTTGAGGAAacatcttttctgattgaaactctctccgggc t" /listShort="yutM" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(3172514..3172533) /Source="Nicolas_upshift_promotors" /id="U2520" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.843156843156843" /psig="0.999000999001" /xcortree=2385 /SigmaFactorBS="aaggagcttttatgtatgaaaaacgggggataattgtATTGt gtccgcttataatAGCTTTTATACTAAGAAAAAgaaaaaaagttggaggcacctatga a" /listShort="dapF, yutM" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3172528) /Source="Nicolas_upshifts" /id="U2520" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.843156843156843" /psig="0.999000999001" /xcortree=2385 /SigmaFactorBS="aaggagcttttatgtatgaaaaacgggggataattgtATTGt gtccgcttataatAGCTTTTATACTAAGAAAAAgaaaaaaagttggaggcacctatga a" /listShort="dapF, yutM" /GFF_Attribute="listLong" promotor_-35 complement(3172548..3172551) /Source="Nicolas_upshift_promotors" /id="U2520" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.843156843156843" /psig="0.999000999001" /xcortree=2385 /SigmaFactorBS="aaggagcttttatgtatgaaaaacgggggataattgtATTGt gtccgcttataatAGCTTTTATACTAAGAAAAAgaaaaaaagttggaggcacctatga a" /listShort="dapF, yutM" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3172615..3173829) /gene="yutK" /locus_tag="BSU_32180" /old_locus_tag="BSU32180" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative Na+(H+)/nucleoside cotransporter" /protein_id="NP_391098.1" /db_xref="EnsemblGenomes-Gn:BSU32180" /db_xref="EnsemblGenomes-Tr:CAB15208" /db_xref="GOA:O32115" /db_xref="InterPro:IPR002668" /db_xref="InterPro:IPR008276" /db_xref="InterPro:IPR011657" /db_xref="InterPro:IPR018270" /db_xref="SubtiList:BG14047" /db_xref="UniProtKB/Swiss-Prot:O32115" /translation="MNVLWGLLGAVAIIAIAFLFSEKKSNIKIRTVIVGLCTQVAFGY IVLKWEAGRAVFLWFSSRVQLLIDYANEGISFIFGPLLKVGDSPAFALSVLPVIIFFS ALIAVLYHLKIMQLVFRVIGGGLSKLLGTSKTESLAAAANIFVGQSESPLVIKPLIAG LTRSELFTIMTSGLSAVAGSTLFGYALLGIPIEYLLAASFMAAPAGLVFGKLIIPETE KTQTVKSDFKMDEGEGAANVIDAAAKGASTGLQIALNVGAMLLAFVALIAVVNGILGG AFGLFGLKGVTLESILGYVFSPIAFLIGVPWHEALQAGSYIGQKLVLNEFVAYSNFGS HIGEFSKKTATIISFALCGFANFSSIAIMLGTLGGLAPSRRSDIARLGLKAVLAGTLA NLLSAAIAGMFI*" gene complement(3172615..3173829) /gene="yutK" /locus_tag="BSU_32180" /old_locus_tag="BSU32180" promotor_-35 3173164..3173170 /Source="Nicolas_upshift_promotors" /id="U2521" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=205 /SigmaFactorBS="tcgccttcatccattttgaaatcgctttttacGGTTTGCgtt ttttccgtttcGGGTATAATCAATTTACCAaagactagtccagctggagcagccataa a" /listShort="S1243, S1244, yutJ" /listLong="yutI" /label="promotor_-35" promotor_-10 3173185..3173203 /Source="Nicolas_upshift_promotors" /id="U2521" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=205 /SigmaFactorBS="tcgccttcatccattttgaaatcgctttttacGGTTTGCgtt ttttccgtttcGGGTATAATCAATTTACCAaagactagtccagctggagcagccataa a" /listShort="S1243, S1244, yutJ" /listLong="yutI" /label="promotor_-10" upshifts 3173192 /Source="Nicolas_upshifts" /id="U2521" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=205 /SigmaFactorBS="tcgccttcatccattttgaaatcgctttttacGGTTTGCgtt ttttccgtttcGGGTATAATCAATTTACCAaagactagtccagctggagcagccataa a" /listShort="S1243, S1244, yutJ" /listLong="yutI" S_feature 3173196..3173965 /Source="Nicolas_S_feature" /locus_tag="new_3307598_3308367" /HighExp="Etha, Salt, Gly, M9-stat, Sw, LoTm, B60, BC, Heat, S0" /AntisenseName="yutK" /AntisenseCor="-0.36240965013078302" /AntisenseRegPval="-9" /CDS_PredictionProba="NA" /TUshortSig="SigB" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1243" promotor_-10 complement(3173866..3173885) /Source="Nicolas_upshift_promotors" /id="U2522" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.924075924075924" /psig="0.998001998001998" /xcortree=2478 /SigmaFactorBS="ccgtacaaaagaactaaaaaaatgTGTAGACAtcaaaaaata ttatTGTTATCGTATAAAAGATATttttttaaataaaatttaagaggtgtacgagtat t" /listShort="yutK" /listLong="dapF, yutM" /label="promotor_-10" upshifts complement(3173871) /Source="Nicolas_upshifts" /id="U2522" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.924075924075924" /psig="0.998001998001998" /xcortree=2478 /SigmaFactorBS="ccgtacaaaagaactaaaaaaatgTGTAGACAtcaaaaaata ttatTGTTATCGTATAAAAGATATttttttaaataaaatttaagaggtgtacgagtat t" /listShort="yutK" /listLong="dapF, yutM" promotor_-35 complement(3173900..3173907) /Source="Nicolas_upshift_promotors" /id="U2522" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.924075924075924" /psig="0.998001998001998" /xcortree=2478 /SigmaFactorBS="ccgtacaaaagaactaaaaaaatgTGTAGACAtcaaaaaata ttatTGTTATCGTATAAAAGATATttttttaaataaaatttaagaggtgtacgagtat t" /listShort="yutK" /listLong="dapF, yutM" /label="promotor_-35" downshifts 3173922 /Source="Nicolas_upshifts" /id="D1668" /incds=0 /nref=3 /ntot=58 /MaxReadThrough="4.13852" /MaxDrop="3.94079" /score="20.5760616" /energy="-10.5" /TU="U2521" /idTUdmin="U2521" /TUdmin="-1913" /isTUend="FALSE" CDS complement(3173966..3174202) /gene="yuzB" /locus_tag="BSU_32190" /old_locus_tag="BSU32190" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_391099.1" /db_xref="EnsemblGenomes-Gn:BSU32190" /db_xref="EnsemblGenomes-Tr:CAB15209" /db_xref="InterPro:IPR009910" /db_xref="InterPro:IPR022916" /db_xref="SubtiList:BG14051" /db_xref="UniProtKB/Swiss-Prot:O32116" /translation="MNPMIEFCVSNLAHGSQEARAILEKDPNLDVLEYGCLSYCGTCM ESLFALVNGEVVMGETPAELVENIYTFIEENPMF*" gene complement(3173966..3174202) /gene="yuzB" /locus_tag="BSU_32190" /old_locus_tag="BSU32190" S_feature 3173967..3174383 /Source="Nicolas_S_feature" /locus_tag="new_3308369_3308785" /HighExp="Salt, LoTm, Gly, Etha, Sw, Heat, S0, C30, M9-stat, Mal" /AntisenseName="yuzB" /AntisenseCor="-5.6824456709843603E-2" /AntisenseRegPval="-0.5" /CDS_PredictionProba="NA" /TUshortSig="SigB" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1244" downshifts complement(3173984) /Source="Nicolas_upshifts" /id="D1669" /incds=0 /nref=175 /ntot=239 /MaxReadThrough="1.28789" /MaxDrop="7.32368" /score="41.4640292" /energy="-10.5" /TU="NA" /idTUdmin="U2523" /TUdmin="-8" /isTUend="TRUE" promotor_-10 complement(3174167..3174168) /Source="Nicolas_upshift_promotors" /id="U2523" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.276723276723277" /psig="0.122877122877123" /xcortree=3156 /SigmaFactorBS="cgcgataatggacatatgtgaggtgaaaccgcatgaatccaa tgattgaattttgtgtCAGCAatcTGgctcacggctctcaggaagcccgggcgatttt g" /listShort="yuzB" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 complement(3174172..3174176) /Source="Nicolas_upshift_promotors" /id="U2523" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.276723276723277" /psig="0.122877122877123" /xcortree=3156 /SigmaFactorBS="cgcgataatggacatatgtgaggtgaaaccgcatgaatccaa tgattgaattttgtgtCAGCAatcTGgctcacggctctcaggaagcccgggcgatttt g" /listShort="yuzB" /GFF_Attribute="listLong" /label="promotor_-35" upshifts complement(3174174) /Source="Nicolas_upshifts" /id="U2523" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.276723276723277" /psig="0.122877122877123" /xcortree=3156 /SigmaFactorBS="cgcgataatggacatatgtgaggtgaaaccgcatgaatccaa tgattgaattttgtgtCAGCAatcTGgctcacggctctcaggaagcccgggcgatttt g" /listShort="yuzB" /GFF_Attribute="listLong" promotor_-10 complement(3174217..3174236) /Source="Nicolas_upshift_promotors" /id="U2524" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.993006993006993" /psig=1 /xcortree=2043 /SigmaFactorBS="taaattttgaatcatccgttgTCTTTGACgaatagtgaaaaa TTCGCGATAATGGACATATGtgaggtgaaaccgcatgaatccaatgattgaattttgt g" /listShort="yuzB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3174218) /Source="Nicolas_upshifts" /id="U2524" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.993006993006993" /psig=1 /xcortree=2043 /SigmaFactorBS="taaattttgaatcatccgttgTCTTTGACgaatagtgaaaaa TTCGCGATAATGGACATATGtgaggtgaaaccgcatgaatccaatgattgaattttgt g" /listShort="yuzB" /GFF_Attribute="listLong" promotor_-35 complement(3174250..3174257) /Source="Nicolas_upshift_promotors" /id="U2524" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.993006993006993" /psig=1 /xcortree=2043 /SigmaFactorBS="taaattttgaatcatccgttgTCTTTGACgaatagtgaaaaa TTCGCGATAATGGACATATGtgaggtgaaaccgcatgaatccaatgattgaattttgt g" /listShort="yuzB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 3174360..3174365 /Source="Nicolas_upshift_promotors" /id="U2525" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.35964035964036" /psig=1 /xcortree=2314 /SigmaFactorBS="tttcaggctaaattgtaggttattttgaaactattATTGTGa ttttagatcaaaTTCGATATAATTCTAGATGTtattttacatagttcgtattttcttc a" /listShort="yutJ" /listLong="yutI" /label="promotor_-35" promotor_-10 3174379..3174398 /Source="Nicolas_upshift_promotors" /id="U2525" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.35964035964036" /psig=1 /xcortree=2314 /SigmaFactorBS="tttcaggctaaattgtaggttattttgaaactattATTGTGa ttttagatcaaaTTCGATATAATTCTAGATGTtattttacatagttcgtattttcttc a" /listShort="yutJ" /listLong="yutI" /label="promotor_-10" upshifts 3174385 /Source="Nicolas_upshifts" /id="U2525" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.35964035964036" /psig=1 /xcortree=2314 /SigmaFactorBS="tttcaggctaaattgtaggttattttgaaactattATTGTGa ttttagatcaaaTTCGATATAATTCTAGATGTtattttacatagttcgtattttcttc a" /listShort="yutJ" /listLong="yutI" CDS 3174465..3175532 /gene="yutJ" /locus_tag="BSU_32200" /old_locus_tag="BSU32200" /EC_number="1.6.-.-" /function="16.10: Respire" /function="16.7: Manage energy" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 17015645; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative NADH dehydrogenase" /protein_id="NP_391100.2" /db_xref="EnsemblGenomes-Gn:BSU32200" /db_xref="EnsemblGenomes-Tr:CAB15210" /db_xref="GOA:O32117" /db_xref="InterPro:IPR023753" /db_xref="InterPro:IPR036188" /db_xref="SubtiList:BG14046" /db_xref="UniProtKB/Swiss-Prot:O32117" /translation="MKKLVLIGGGYGNMRVLHRLLPNQLPDDVSITLIDRNPYHCLKT EYYALAAGTISDHHIRVSFPEHPRLDVQYGDITSIDIVQKQVLFQDREPISYDDAIIG LGCEDKYHNVPGAPEFTYSIQTIDQSRETYQKLNNLSANATVAIVGAGLSGVELASEL RESRDDLNIILFDRGNLILSSFPERLSKYVQKWFEEHGVRIINRANITKVEEGVVYNH DDPISADAIVWTAGIQPNKVVRDLDVEKDAQGRIVLTPHHNLPGDEHLYVVGDCASLP HAPSAQLAEAQAEQIVQILQKRWNGEALPESMPQFKLKGVLGSLGKKAGFGLVADRPL IGRVPRMLKSGLLWMYKHHNG*" gene 3174465..3175532 /gene="yutJ" /locus_tag="BSU_32200" /old_locus_tag="BSU32200" downshifts 3175516 /Source="Nicolas_upshifts" /id="D1670" /incds=0 /nref=4 /ntot=110 /MaxReadThrough="3.51945" /MaxDrop="3.02708" /score="6.15657679" /energy="-10.8" /TU="U2521,U2525" /idTUdmin="U2521" /TUdmin="-319" /isTUend="FALSE" CDS complement(3175558..3175884) /gene="yuzD" /locus_tag="BSU_32210" /old_locus_tag="BSU32210" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 11551182; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative sulfur oxido-reduction management enzyme" /protein_id="NP_391101.1" /db_xref="EnsemblGenomes-Gn:BSU32210" /db_xref="EnsemblGenomes-Tr:CAB15211" /db_xref="InterPro:IPR009190" /db_xref="InterPro:IPR036249" /db_xref="SubtiList:BG14053" /db_xref="UniProtKB/Swiss-Prot:O32118" /translation="MMKPVMLSVYGAENVCASCVNMPTAKDTYEWLEAALKRKYPNQP FEMQYIDIHEPPDNEHAKELAEKIRNDEYFYPLVLVEDKIVGEGNPKLKDVYEEMEKH GYTENR*" gene complement(3175558..3175884) /gene="yuzD" /locus_tag="BSU_32210" /old_locus_tag="BSU32210" downshifts complement(3175581) /Source="Nicolas_upshifts" /id="D1671" /incds=0 /nref=4 /ntot=180 /MaxReadThrough="1.63835" /MaxDrop="3.17377" /score="-8.05690984" /energy="-10.8" /TU="NA" /idTUdmin="U2526" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(3175916..3175935) /Source="Nicolas_upshift_promotors" /id="U2526" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.507492507492508" /psig="0.995004995004995" /xcortree=2229 /SigmaFactorBS="tatagcacattcagacttcaacacaaaaacggttttttTCTA TAAAaacgcccttaggCTCTGTATACTTAAAAGAAAggacttacataggagaaggggg c" /listShort="yuzD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3175933) /Source="Nicolas_upshifts" /id="U2526" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.507492507492508" /psig="0.995004995004995" /xcortree=2229 /SigmaFactorBS="tatagcacattcagacttcaacacaaaaacggttttttTCTA TAAAaacgcccttaggCTCTGTATACTTAAAAGAAAggacttacataggagaaggggg c" /listShort="yuzD" /GFF_Attribute="listLong" promotor_-35 complement(3175948..3175955) /Source="Nicolas_upshift_promotors" /id="U2526" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.507492507492508" /psig="0.995004995004995" /xcortree=2229 /SigmaFactorBS="tatagcacattcagacttcaacacaaaaacggttttttTCTA TAAAaacgcccttaggCTCTGTATACTTAAAAGAAAggacttacataggagaaggggg c" /listShort="yuzD" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 3175968..3175972 /Source="Nicolas_upshift_promotors" /id="U2527" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.924075924075924" /psig=1 /xcortree=593 /SigmaFactorBS="acagagcctaagggcgtttttatagaaaaaaaccgtttTTGT GttgaagtctgaaTGTGCTATAATAGGGAAAGCaactttgcaaaccaaacaatagatt t" /listShort="yutI" /GFF_Attribute="listLong" /label="promotor_-35" CDS 3175984..3176319 /gene="yutI" /locus_tag="BSU_32220" /old_locus_tag="BSU32220" /function="16.6: Maintain" /function="16.13: Shape" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 17237162, 21749987; Product type f: factor" /codon_start=1 /transl_table=11 /product="putative iron-sulfur scaffold protein" /protein_id="NP_391102.1" /db_xref="EnsemblGenomes-Gn:BSU32220" /db_xref="EnsemblGenomes-Tr:CAB15212" /db_xref="GOA:O32119" /db_xref="InterPro:IPR001075" /db_xref="InterPro:IPR034904" /db_xref="SubtiList:BG14045" /db_xref="UniProtKB/Swiss-Prot:O32119" /translation="MCYNRESNFANQTIDFYCYTEYNGFMTTKGANVMTEVEMKEQVQ EVLDKLRPFLLRDGGDCELVDVDEGIVKLRLLGACGSCPSSTITLKAGIERALLEEVP GVVEVEQVF*" gene 3175984..3176319 /gene="yutI" /locus_tag="BSU_32220" /old_locus_tag="BSU32220" promotor_-10 3175985..3176004 /Source="Nicolas_upshift_promotors" /id="U2527" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.924075924075924" /psig=1 /xcortree=593 /SigmaFactorBS="acagagcctaagggcgtttttatagaaaaaaaccgtttTTGT GttgaagtctgaaTGTGCTATAATAGGGAAAGCaactttgcaaaccaaacaatagatt t" /listShort="yutI" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3175990 /Source="Nicolas_upshifts" /id="U2527" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.924075924075924" /psig=1 /xcortree=593 /SigmaFactorBS="acagagcctaagggcgtttttatagaaaaaaaccgtttTTGT GttgaagtctgaaTGTGCTATAATAGGGAAAGCaactttgcaaaccaaacaatagatt t" /listShort="yutI" /GFF_Attribute="listLong" downshifts complement(3176109) /Source="Nicolas_upshifts" /id="D1672" /incds=1 /nref=1 /ntot=5 /MaxReadThrough="1.28655" /MaxDrop="3.45909" /score="7.3681553" /energy="-21.2" /TU="NA" /idTUdmin="U2528" /TUdmin=264 /isTUend="FALSE" downshifts 3176297 /Source="Nicolas_upshifts" /id="D1673" /incds=0 /nref=258 /ntot=281 /MaxReadThrough="3.6035" /MaxDrop="7.98922" /score="39.7008566" /energy="-19.5" /TU="U2527" /idTUdmin="U2527" /TUdmin="-220" /isTUend="FALSE" CDS complement(3176361..3178334) /gene="yuxL" /locus_tag="BSU_32230" /old_locus_tag="BSU32230" /EC_number="3.4.-.-" /function="16.11: Scavenge (Catabolism)" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 8576092, 11406580; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative acylaminoacyl-peptidase" /protein_id="NP_391103.2" /db_xref="EnsemblGenomes-Gn:BSU32230" /db_xref="EnsemblGenomes-Tr:CAB15213" /db_xref="GOA:P39839" /db_xref="InterPro:IPR001375" /db_xref="InterPro:IPR011659" /db_xref="InterPro:IPR029058" /db_xref="SubtiList:BG10463" /db_xref="UniProtKB/Swiss-Prot:P39839" /translation="MKKLITADDITAIVSVTDPQYAPDGTRAAYVKSQVNQEKDSYTS NIWIYETKTGGSVPWTHGEKRSTDPRWSPDGRTLAFISDREGDAAQLYIMSTEGGEAR KLTDIPYGVSKPLWSPDGESILVTVSLGEGESIDDREKTEQDSYEPVEVQGLSYKRDG KGLTRGAYAQLVLVSVKSGEMKELTSHKADHGDPAFSPDGKWLVFSANLTETDDASKP HDVYIMSLESGDLKQVTPHRGSFGSSSFSPDGRYLALLGNEKEYKNATLSKAWLYDIE QGRLTCLTEMLDVHLADALIGDSLIGGAEQRPIWTKDSQGFYVIGTDQGSTGIYYISI EGLVYPIRLEKEYINSFSLSPDEQHFIASVTKPDRPSELYSIPLGQEEKQLTGANDKF VREHTISIPEEIQYATEDGVMVNGWLMRPAQMEGETTYPLILNIHGGPHMMYGHTYFH EFQVLAAKGYAVVYINPRGSHGYGQEFVNAVRGDYGGKDYDDVMQAVDEAIKRDPHID PKRLGVTGGSYGGFMTNWIVGQTNRFKAAVTQRSISNWISFHGVSDIGYFFTDWQLEH DMFEDTEKLWDRSPLKYAANVETPLLILHGERDDRCPIEQAEQLFIALKKMGKETKLV RFPNASHNLSRTGHPRQRIKRLNYISSWFDQHL*" gene complement(3176361..3178334) /gene="yuxL" /locus_tag="BSU_32230" /old_locus_tag="BSU32230" downshifts complement(3176373) /Source="Nicolas_upshifts" /id="D1674" /incds=0 /nref=19 /ntot=114 /MaxReadThrough="1.79797" /MaxDrop="3.85507" /score="7.3681553" /energy="-21.2" /TU="NA" /idTUdmin="U2528" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(3178349..3178367) /Source="Nicolas_upshift_promotors" /id="U2528" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp=1 /psig=1 /xcortree=501 /SigmaFactorBS="agcgttcctcagcgtcagcggagggcgcttttttttgctgga gatAAAGGAGTTtttatttagaaAAACGAAATACATGTAAAAaggaggagatgaatat g" /listShort="yuxL" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3178372) /Source="Nicolas_upshifts" /id="U2528" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp=1 /psig=1 /xcortree=501 /SigmaFactorBS="agcgttcctcagcgtcagcggagggcgcttttttttgctgga gatAAAGGAGTTtttatttagaaAAACGAAATACATGTAAAAaggaggagatgaatat g" /listShort="yuxL" /GFF_Attribute="listLong" promotor_-35 complement(3178379..3178387) /Source="Nicolas_upshift_promotors" /id="U2528" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp=1 /psig=1 /xcortree=501 /SigmaFactorBS="agcgttcctcagcgtcagcggagggcgcttttttttgctgga gatAAAGGAGTTtttatttagaaAAACGAAATACATGTAAAAaggaggagatgaatat g" /listShort="yuxL" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3178442..3179371) /gene="thrB" /locus_tag="BSU_32240" /old_locus_tag="BSU32240" /EC_number="2.7.1.39" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:3098560, 22720735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 3098560, 22720735; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="homoserine kinase" /protein_id="NP_391104.1" /db_xref="EnsemblGenomes-Gn:BSU32240" /db_xref="EnsemblGenomes-Tr:CAB15214" /db_xref="GOA:P04948" /db_xref="InterPro:IPR000870" /db_xref="InterPro:IPR006203" /db_xref="InterPro:IPR006204" /db_xref="InterPro:IPR013750" /db_xref="InterPro:IPR014721" /db_xref="InterPro:IPR020568" /db_xref="InterPro:IPR036554" /db_xref="SubtiList:BG10462" /db_xref="UniProtKB/Swiss-Prot:P04948" /translation="MNEADMLFSVTVPGSTANLGPGFDSVGMALSRYLKLTVFESDKW SFEAETETVAGIPAGTDNLIYQVAKRTADLYGKEMPPVHVKVWSDIPLARGLGSSAAA IVAAIELADELCGLKLSEADKLHLASLEEGHPDNAGASLVGGLVIGLHEDDETQMIRV PNADIDVVVVIPFYEVLTRDARDVLPKEFPYADAVKASAVSNILIAAIMSKDWPLVGK IMKKDMFHQPYRAMLVPELSKVEHVAEMKGAYGTALSGAGPTILVMTEKGKGEELKEQ LALHFPHCEVDALTVPKEGSIIERNPLYQVKSV*" gene complement(3178442..3179371) /gene="thrB" /locus_tag="BSU_32240" /old_locus_tag="BSU32240" downshifts complement(3178455) /Source="Nicolas_upshifts" /id="D1675" /incds=0 /nref=222 /ntot=261 /MaxReadThrough="2.39521" /MaxDrop="7.03759" /score="15.5945196" /energy="-10.3" /TU="NA" /idTUdmin="U2530" /TUdmin="-14" /isTUend="TRUE" CDS complement(3179368..3180426) /gene="thrC" /locus_tag="BSU_32250" /old_locus_tag="BSU32250" /EC_number="4.2.3.1" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:3098560, 3139660, 8768250" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 3098560, 3139660, 8768250; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="threonine synthase" /protein_id="NP_391105.1" /db_xref="EnsemblGenomes-Gn:BSU32250" /db_xref="EnsemblGenomes-Tr:CAB15215" /db_xref="GOA:P04990" /db_xref="InterPro:IPR000634" /db_xref="InterPro:IPR001926" /db_xref="InterPro:IPR004450" /db_xref="InterPro:IPR026260" /db_xref="InterPro:IPR036052" /db_xref="SubtiList:BG10461" /db_xref="UniProtKB/Swiss-Prot:P04990" /translation="MWKGLIHQYKEFLPVTDQTPALTLHEGNTPLIHLPKLSEQLGIE LHVKTEGVNPTGSFKDRGMVMAVAKAKEEGNDTIMCASTGNTSAAAAAYAARANMKCI VIIPNGKIAFGKLAQAVMYGAEIIAIDGNFDDALKIVRSICEKSPIALVNSVNPYRIE GQKTAAFEVCEQLGEAPDVLAIPVGNAGNITAYWKGFKEYHEKNGTGLPKMRGFEAEG AAAIVRNEVIENPETIATAIRIGNPASWDKAVKAAEESNGKIDEVTDDEILHAYQLIA RVEGVFAEPGSCASIAGVLKQVKSGEIPKGSKVVAVLTGNGLKDPNTAVDISEIKPVT LPTDEDSILEYVKGAARV*" gene complement(3179368..3180426) /gene="thrC" /locus_tag="BSU_32250" /old_locus_tag="BSU32250" CDS complement(3180426..3181727) /gene="hom" /locus_tag="BSU_32260" /old_locus_tag="BSU32260" /EC_number="1.1.1.3" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:3139660, 27299409" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 3139660, 27299409; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="homoserine dehydrogenase" /protein_id="NP_391106.1" /db_xref="EnsemblGenomes-Gn:BSU32260" /db_xref="EnsemblGenomes-Tr:CAB15216" /db_xref="GOA:P19582" /db_xref="InterPro:IPR001342" /db_xref="InterPro:IPR002912" /db_xref="InterPro:IPR005106" /db_xref="InterPro:IPR016204" /db_xref="InterPro:IPR019811" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG10460" /db_xref="UniProtKB/Swiss-Prot:P19582" /translation="MKAIRVGLLGLGTVGSGVVKIIQDHQDKLMHQVGCPVTIKKVLV KDLEKKREVDLPKEVLTTEVYDVIDDPDVDVVIEVIGGVEQTKQYLVDALRSKKHVVT ANKDLMAVYGSELLAEAKENGCDIYFEASVAGGIPILRTLEEGLSSDRITKMMGIVNG TTNFILTKMIKEKSPYEEVLKEAQDLGFAEADPTSDVEGLDAARKMAILARLGFSMNV DLEDVKVKGISQITDEDISFSKRLGYTMKLIGIAQRDGSKIEVSVQPTLLPDHHPLSA VHNEFNAVYVYGEAVGETMFYGPGAGSMPTATSVVSDLVAVMKNMRLGVTGNSFVGPQ YEKNMKSPSDIYAQQFLRIHVKDEVGSFSKITSVFSERGVSFEKILQLPIKGHDELAE IVIVTHHTSEADFSDILQNLNDLEVVQEVKSTYRVEGNGWS*" gene complement(3180426..3181727) /gene="hom" /locus_tag="BSU_32260" /old_locus_tag="BSU32260" promotor_-35 3181612..3181621 /Source="Nicolas_upshift_promotors" /id="U2529" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1386 /SigmaFactorBS="tctctaaatcttttacaagcactttttttATCGTAACCGgac agccgacctgaTGCATAAGCTTATCCTGATGgtcttgaataattttaacgacaccgct t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3181636..3181655 /Source="Nicolas_upshift_promotors" /id="U2529" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1386 /SigmaFactorBS="tctctaaatcttttacaagcactttttttATCGTAACCGgac agccgacctgaTGCATAAGCTTATCCTGATGgtcttgaataattttaacgacaccgct t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3181643 /Source="Nicolas_upshifts" /id="U2529" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1386 /SigmaFactorBS="tctctaaatcttttacaagcactttttttATCGTAACCGgac agccgacctgaTGCATAAGCTTATCCTGATGgtcttgaataattttaacgacaccgct t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" S_feature complement(3181728..3181809) /Source="Nicolas_S_feature" /locus_tag="new_3316130_3316211_c" /HighExp="T3.0H, T2.30H, T3.30H, S2, C90, T4.0H, BMM, SMM, MG 120, UNK1" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigEF" /TUshortPSig="1, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S1245" promotor_-10 complement(3181794..3181813) /Source="Nicolas_upshift_promotors" /id="U2530" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.986013986013986" /psig=1 /xcortree=3043 /SigmaFactorBS="agcgtttacattcgcaaaattcagcctaatgatgTCTTGTCA aaacaggagcgggcTTATATAATGTTTGTAACTTatatgtctgtgttgagttaacaat t" /listShort="S1245, hom, thrC, thrB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3181809) /Source="Nicolas_upshifts" /id="U2530" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.986013986013986" /psig=1 /xcortree=3043 /SigmaFactorBS="agcgtttacattcgcaaaattcagcctaatgatgTCTTGTCA aaacaggagcgggcTTATATAATGTTTGTAACTTatatgtctgtgttgagttaacaat t" /listShort="S1245, hom, thrC, thrB" /GFF_Attribute="listLong" S_feature complement(3181811..3181927) /Source="Nicolas_S_feature" /locus_tag="new_3316213_3316329_c" /HighExp="S5, S3, S4, S7, S6, S8, BT, B36, LoTm, T5.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigEF" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1246" promotor_-35 complement(3181828..3181835) /Source="Nicolas_upshift_promotors" /id="U2530" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.986013986013986" /psig=1 /xcortree=3043 /SigmaFactorBS="agcgtttacattcgcaaaattcagcctaatgatgTCTTGTCA aaacaggagcgggcTTATATAATGTTTGTAACTTatatgtctgtgttgagttaacaat t" /listShort="S1245, hom, thrC, thrB" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3181928..3182947) /gene="cotNH" /locus_tag="BSU_32270" /old_locus_tag="BSU32270" /function="16.3: Control" /function="16.13: Shape" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:15231775, 22882546" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15231775, 22882546; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="spore coat-associated protein" /protein_id="NP_391107.1" /db_xref="EnsemblGenomes-Gn:BSU32270" /db_xref="EnsemblGenomes-Tr:CAB15217" /db_xref="GOA:O32123" /db_xref="InterPro:IPR011009" /db_xref="InterPro:IPR014254" /db_xref="SubtiList:BG14044" /db_xref="UniProtKB/Swiss-Prot:O32123" /translation="MVKGTIKEKYGIHIRQLSMYQHTYQCFQTPNSYFLIVPVSQFSE TELAELYYMSQYLQEQSDPYVSVFIFTKEGELTFEHEGKTYALLKAAPPYSNRAFSIG AELAEFHRKGRGYPYEVKAAGRIGQWKDLWGKRIDQLEAFWQRKVQTPPHEPFDKKMI ESFPYYLGLSENAIQYLVDTELDDKPQAADSGTICHQRMERHTWSPESLIRIPADWVF DHASRDLAEYMRHTFLHHRQDFNQQGFLFLQEYEQVTPLSSFSKRLLYSRLLFPLHYF EIVESYYMSSESEKHYFEEQLDFILNDCGRYEQFLNTAQEFMNMRAQKLFVPRVSWLG KGSSR*" gene complement(3181928..3182947) /gene="cotNH" /locus_tag="BSU_32270" /old_locus_tag="BSU32270" promotor_-35 3182755..3182760 /Source="Nicolas_upshift_promotors" /id="U2531" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.813186813186813" /psig="0.813186813186813" /xcortree=1020 /SigmaFactorBS="cagttcaccttcttttgtaaagataaaaaccgaaaCGTATGg gtcactttgttcttGTAAATACTGACTCATGTAataaagctccgccagctctgtttct g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3182776..3182794 /Source="Nicolas_upshift_promotors" /id="U2531" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.813186813186813" /psig="0.813186813186813" /xcortree=1020 /SigmaFactorBS="cagttcaccttcttttgtaaagataaaaaccgaaaCGTATGg gtcactttgttcttGTAAATACTGACTCATGTAataaagctccgccagctctgtttct g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3182780 /Source="Nicolas_upshifts" /id="U2531" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.813186813186813" /psig="0.813186813186813" /xcortree=1020 /SigmaFactorBS="cagttcaccttcttttgtaaagataaaaaccgaaaCGTATGg gtcactttgttcttGTAAATACTGACTCATGTAataaagctccgccagctctgtttct g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 complement(3182970..3182988) /Source="Nicolas_upshift_promotors" /id="U2532" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1126 /SigmaFactorBS="ttgcgccttcttcggattaaaatatgtaTTCATAattccggc tgtgtatGACTACGATGTGATGAGCCctaattcaacaggcaggtgatcatggtgaaag g" /listShort="yutH, S1246, S1245, hom, thrC, thrB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3182977) /Source="Nicolas_upshifts" /id="U2532" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1126 /SigmaFactorBS="ttgcgccttcttcggattaaaatatgtaTTCATAattccggc tgtgtatGACTACGATGTGATGAGCCctaattcaacaggcaggtgatcatggtgaaag g" /listShort="yutH, S1246, S1245, hom, thrC, thrB" /GFF_Attribute="listLong" promotor_-35 3182986..3182991 /Source="Nicolas_upshift_promotors" /id="U2533" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=1124 /SigmaFactorBS="tgatcacctgcctgttgaattagggctcatcacatcgtaGTC ATAcacagccggaattatGAATACATATTTTAATCCGaagaaggcgcaagaaaaagtc g" /listShort="S1247, yutG" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 complement(3183004..3183009) /Source="Nicolas_upshift_promotors" /id="U2532" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1126 /SigmaFactorBS="ttgcgccttcttcggattaaaatatgtaTTCATAattccggc tgtgtatGACTACGATGTGATGAGCCctaattcaacaggcaggtgatcatggtgaaag g" /listShort="yutH, S1246, S1245, hom, thrC, thrB" /GFF_Attribute="listLong" /label="promotor_-35" S_feature 3183007..3183071 /Source="Nicolas_S_feature" /locus_tag="new_3317409_3317473" /HighExp="S4, S5, S3, S6, S7, B36, S8, LoTm, Pyr, G/S" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigEF" /TUshortPSig="0.998" /TUlongSig="NA" /TUlongPSig="NA" /label="S1247" promotor_-10 3183007..3183025 /Source="Nicolas_upshift_promotors" /id="U2533" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=1124 /SigmaFactorBS="tgatcacctgcctgttgaattagggctcatcacatcgtaGTC ATAcacagccggaattatGAATACATATTTTAATCCGaagaaggcgcaagaaaaagtc g" /listShort="S1247, yutG" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3183007 /Source="Nicolas_upshifts" /id="U2533" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=1124 /SigmaFactorBS="tgatcacctgcctgttgaattagggctcatcacatcgtaGTC ATAcacagccggaattatGAATACATATTTTAATCCGaagaaggcgcaagaaaaagtc g" /listShort="S1247, yutG" /GFF_Attribute="listLong" promotor_-35 3183044..3183053 /Source="Nicolas_upshift_promotors" /id="U2534" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.86013986013986" /psig="0.86013986013986" /xcortree=1330 /SigmaFactorBS="atattttaatccgaagaaggcgcaagaaaaaGTCGTAAACTt ctcaagcatttTGTATAAACTAGTAAAAAAGattgggtgaagctgatgtcagaaaacg a" /listShort="yutG" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3183066..3183085 /Source="Nicolas_upshift_promotors" /id="U2534" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.86013986013986" /psig="0.86013986013986" /xcortree=1330 /SigmaFactorBS="atattttaatccgaagaaggcgcaagaaaaaGTCGTAAACTt ctcaagcatttTGTATAAACTAGTAAAAAAGattgggtgaagctgatgtcagaaaacg a" /listShort="yutG" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3183073 /Source="Nicolas_upshifts" /id="U2534" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.86013986013986" /psig="0.86013986013986" /xcortree=1330 /SigmaFactorBS="atattttaatccgaagaaggcgcaagaaaaaGTCGTAAACTt ctcaagcatttTGTATAAACTAGTAAAAAAGattgggtgaagctgatgtcagaaaacg a" /listShort="yutG" /GFF_Attribute="listLong" CDS 3183100..3183600 /gene="yutG" /locus_tag="BSU_32280" /old_locus_tag="BSU32280" /function="16.8: Protect" /function="16.6: Maintain" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 22333191; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative phosphatidylglycerophosphatase" /protein_id="NP_391108.1" /db_xref="EnsemblGenomes-Gn:BSU32280" /db_xref="EnsemblGenomes-Tr:CAB15218" /db_xref="GOA:O32124" /db_xref="InterPro:IPR007686" /db_xref="InterPro:IPR026038" /db_xref="InterPro:IPR036681" /db_xref="SubtiList:BG14043" /db_xref="UniProtKB/Swiss-Prot:O32124" /translation="MSENEQFSQMEAKARARMKERGVEVSDIAELVFFLQKKYHPDLT IDECTLNVNRVLAKREVQNAILTGIELDVLAEQKKLSEPLQTMLEIDESLYGVDEVLA FSIVNIYGSIGFTNYGYIDKEKPGILKRLNDKSTGECHTFLDDIVGAISAAASSRLAH RARHTE*" gene 3183100..3183600 /gene="yutG" /locus_tag="BSU_32280" /old_locus_tag="BSU32280" CDS complement(3183627..3184397) /gene="nucF" /locus_tag="BSU_32290" /old_locus_tag="BSU32290" /EC_number="3.1.3.5" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:15664928, 16766528, 27907199" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15664928, 16766528, 27907199; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="5' nucleotidase, promiscuous" /protein_id="NP_391109.1" /db_xref="EnsemblGenomes-Gn:BSU32290" /db_xref="EnsemblGenomes-Tr:CAB15219" /db_xref="GOA:O32125" /db_xref="InterPro:IPR006354" /db_xref="InterPro:IPR006357" /db_xref="InterPro:IPR023214" /db_xref="InterPro:IPR036412" /db_xref="PDB:3PDW" /db_xref="SubtiList:BG14042" /db_xref="UniProtKB/Swiss-Prot:O32125" /translation="MKTYKGYLIDLDGTMYNGTEKIEEACEFVRTLKDRGVPYLFVTN NSSRTPKQVADKLVSFDIPATEEQVFTTSMATAQHIAQQKKDASVYVIGEEGIRQAIE ENGLTFGGENADFVVVGIDRSITYEKFAVGCLAIRNGARFISTNGDIAIPTERGLLPG NGSLTSVLTVSTGVQPVFIGKPESIIMEQAMRVLGTDVSETLMVGDNYATDIMAGINA GMDTLLVHTGVTKREHMTDDMEKPTHAIDSLTEWIPYI*" gene complement(3183627..3184397) /gene="nucF" /locus_tag="BSU_32290" /old_locus_tag="BSU32290" downshifts complement(3183655) /Source="Nicolas_upshifts" /id="D1676" /incds=0 /nref=137 /ntot=243 /MaxReadThrough="2.15034" /MaxDrop="4.82801" /score="8.09889752" /energy="-15.6" /TU="NA" /idTUdmin="U2535" /TUdmin=0 /isTUend="TRUE" CDS complement(3184426..3184860) /gene="yutE" /locus_tag="BSU_32300" /old_locus_tag="BSU32300" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 27907199" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_391110.1" /db_xref="EnsemblGenomes-Gn:BSU32300" /db_xref="EnsemblGenomes-Tr:CAB15220" /db_xref="InterPro:IPR008201" /db_xref="PDB:1YLM" /db_xref="SubtiList:BG14041" /db_xref="UniProtKB/Swiss-Prot:O32126" /translation="MYFVDRSKIEKTLGFFEHQLALFDSQTDWQSEIGELALQRIGHL LIECILDTGNDMIDGFIMRDPGSYDDIMDILVDEKVVTEKEGDELKKLIAYRKTLVQQ YLLADSGELYRLIKAHQTALQDFPKRIRSYLETELGPVSAFK*" gene complement(3184426..3184860) /gene="yutE" /locus_tag="BSU_32300" /old_locus_tag="BSU32300" CDS complement(3184884..3185159) /gene="yutD" /locus_tag="BSU_32310" /old_locus_tag="BSU32310" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 12770717, 27907199" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_391111.2" /db_xref="EnsemblGenomes-Gn:BSU32310" /db_xref="EnsemblGenomes-Tr:CAB15221" /db_xref="InterPro:IPR009370" /db_xref="PDB:2KL5" /db_xref="SubtiList:BG14040" /db_xref="UniProtKB/Swiss-Prot:O32127" /translation="MILIQNAEFELVHNFKDGFNEEAFKARYSDILNKYDYIVGDWGY GQLRLKGFFDDQNQKATFETKISTLDEYIYEYCNFGCAYFVLKRIRK*" gene complement(3184884..3185159) /gene="yutD" /locus_tag="BSU_32310" /old_locus_tag="BSU32310" promotor_-10 complement(3185179..3185198) /Source="Nicolas_upshift_promotors" /id="U2535" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.65034965034965" /psig=1 /xcortree=2678 /SigmaFactorBS="cctcctcatgtgtagggtagccaaatcgcatgatttattctt tagCAATTGATggggacggggcaaTGAATTATGATAGGAATGAGtgaaaaaagaggtg a" /listShort="yutD, yutE, yutF" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3185204) /Source="Nicolas_upshifts" /id="U2535" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.65034965034965" /psig=1 /xcortree=2678 /SigmaFactorBS="cctcctcatgtgtagggtagccaaatcgcatgatttattctt tagCAATTGATggggacggggcaaTGAATTATGATAGGAATGAGtgaaaaaagaggtg a" /listShort="yutD, yutE, yutF" /GFF_Attribute="listLong" S_feature complement(3185206..3185898) /Source="Nicolas_S_feature" /locus_tag="new_3319608_3320300_c" /HighExp="G135, G150, G180, H2O2, LBGtran, LBGexp, Paraq, dia15, C90, HiOs" /AntisenseName="yutC" /AntisenseCor="-0.57886192731570996" /AntisenseRegPval="-24.7" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1248" promotor_-35 complement(3185212..3185219) /Source="Nicolas_upshift_promotors" /id="U2535" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.65034965034965" /psig=1 /xcortree=2678 /SigmaFactorBS="cctcctcatgtgtagggtagccaaatcgcatgatttattctt tagCAATTGATggggacggggcaaTGAATTATGATAGGAATGAGtgaaaaaagaggtg a" /listShort="yutD, yutE, yutF" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 3185222..3185228 /Source="Nicolas_upshift_promotors" /id="U2536" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.711288711288711" /psig="0.711288711288711" /xcortree=851 /SigmaFactorBS="ataattcattgccccgtccccatcaattgctAAAGAATaaat catgcgatttGGCTACCCTACAcatgaggagggattgataaatgaaacgaaccgctgt c" /listShort="yutC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3185243..3185254 /Source="Nicolas_upshift_promotors" /id="U2536" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.711288711288711" /psig="0.711288711288711" /xcortree=851 /SigmaFactorBS="ataattcattgccccgtccccatcaattgctAAAGAATaaat catgcgatttGGCTACCCTACAcatgaggagggattgataaatgaaacgaaccgctgt c" /listShort="yutC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3185251 /Source="Nicolas_upshifts" /id="U2536" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.711288711288711" /psig="0.711288711288711" /xcortree=851 /SigmaFactorBS="ataattcattgccccgtccccatcaattgctAAAGAATaaat catgcgatttGGCTACCCTACAcatgaggagggattgataaatgaaacgaaccgctgt c" /listShort="yutC" /GFF_Attribute="listLong" CDS 3185274..3185906 /gene="yutC" /locus_tag="BSU_32320" /old_locus_tag="BSU32320" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type lp: lipoprotein" /codon_start=1 /transl_table=11 /product="putative sporulation-related lipoprotein" /protein_id="NP_391112.1" /db_xref="EnsemblGenomes-Gn:BSU32320" /db_xref="EnsemblGenomes-Tr:CAB15222" /db_xref="GOA:O32128" /db_xref="InterPro:IPR019076" /db_xref="SubtiList:BG14039" /db_xref="UniProtKB/Swiss-Prot:O32128" /translation="MKRTAVSLCLLTGLLSGCGGAGLDNAQNVRNQTQNQTKPIHVSD RNEAFNRHNENEQFGYVRYQKEQFDGEQQKTPVMNREETAHMISSLTVQLPHIQDAAT LVTDREALVVYKTDSKNRELTADQVKKTAASVIPRYYHVYISDNPNHMQSVENYSNLG SGSRDIREIMSGTIQEMKTSPQGSPVSENENANGETRQDMKIDRNDKNAR*" gene 3185274..3185906 /gene="yutC" /locus_tag="BSU_32320" /old_locus_tag="BSU32320" downshifts 3185867 /Source="Nicolas_upshifts" /id="D1677" /incds=0 /nref=9 /ntot=30 /MaxReadThrough="1.84979" /MaxDrop="3.55825" /score="-2.38634221" /energy="-9.6" /TU="NA" /idTUdmin="U2536" /TUdmin=0 /isTUend="TRUE" CDS complement(3185922..3186818) /gene="lipA" /locus_tag="BSU_32330" /old_locus_tag="BSU32330" /EC_number="2.8.1.8" /function="16.3: Control" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 15362861, 16835858, 19028902, 19820084, 25341020; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="lipoyl synthase (lipoic acid synthetase)" /protein_id="NP_391113.2" /db_xref="EnsemblGenomes-Gn:BSU32330" /db_xref="EnsemblGenomes-Tr:CAB15223" /db_xref="GOA:O32129" /db_xref="InterPro:IPR003698" /db_xref="InterPro:IPR006638" /db_xref="InterPro:IPR007197" /db_xref="InterPro:IPR013785" /db_xref="InterPro:IPR031691" /db_xref="SubtiList:BG14038" /db_xref="UniProtKB/Swiss-Prot:O32129" /translation="MAKKDEHLRKPEWLKIKLNTNENYTGLKKLMRENNLHTVCEEAK CPNIHECWAVRRTATFMILGSVCTRACRFCAVKTGLPTELDLQEPERVADSVALMNLK HAVITAVARDDQKDGGAGIFAETVRAIRRKSPFTTIEVLPSDMGGNYDNLKTLMDTRP DILNHNIETVRRLTPRVRARATYDRSLEFLRRAKEMQPDIPTKSSIMIGLGETKEEII EVMDDLLANNVDIMAIGQYLQPTKKHLKVQKYYHPDEFAELKEIAMQKGFSHCEAGPL VRSSYHADEQVNEASKKRQAQA*" gene complement(3185922..3186818) /gene="lipA" /locus_tag="BSU_32330" /old_locus_tag="BSU32330" downshifts complement(3185943) /Source="Nicolas_upshifts" /id="D1678" /incds=0 /nref=186 /ntot=261 /MaxReadThrough="3.83236" /MaxDrop="5.33309" /score="14.803008" /energy="-9.6" /TU="U2537" /idTUdmin="U2537" /TUdmin="-726" /isTUend="FALSE" S_feature complement(3186819..3186953) /Source="Nicolas_S_feature" /locus_tag="new_3321221_3321355_c" /HighExp="HiOs, LBGtran, dia15, dia5, C90, Diami, dia0, LBGexp, Heat, HPh" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1249" promotor_-10 complement(3186940..3186959) /Source="Nicolas_upshift_promotors" /id="U2537" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.651348651348651" /psig=1 /xcortree=2669 /SigmaFactorBS="gcaacccggcttaaaaatgtcagtaatcatcttcCCTTGtcg agaaatttttccTATGTTAAAGTGTCTAAAGAaaagactttctttagttagaaaaaca t" /listShort="S1249, lipA, S1248" /listLong="yutD, yutE, yutF" /label="promotor_-10" upshifts complement(3186953) /Source="Nicolas_upshifts" /id="U2537" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.651348651348651" /psig=1 /xcortree=2669 /SigmaFactorBS="gcaacccggcttaaaaatgtcagtaatcatcttcCCTTGtcg agaaatttttccTATGTTAAAGTGTCTAAAGAaaagactttctttagttagaaaaaca t" /listShort="S1249, lipA, S1248" /listLong="yutD, yutE, yutF" promotor_-35 complement(3186975..3186979) /Source="Nicolas_upshift_promotors" /id="U2537" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.651348651348651" /psig=1 /xcortree=2669 /SigmaFactorBS="gcaacccggcttaaaaatgtcagtaatcatcttcCCTTGtcg agaaatttttccTATGTTAAAGTGTCTAAAGAaaagactttctttagttagaaaaaca t" /listShort="S1249, lipA, S1248" /listLong="yutD, yutE, yutF" /label="promotor_-35" promotor_-35 3186993..3186999 /Source="Nicolas_upshift_promotors" /id="U2538" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.99000999000999" /psig="0.99000999000999" /xcortree=866 /SigmaFactorBS="aatttctcgacaagggaagatgattactGACATTTttaagcc gggttgCCGCAAACTATGtgtattcaatatgaaaggagattattttgtgaaagttttg t" /listShort="lytH" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3187013..3187024 /Source="Nicolas_upshift_promotors" /id="U2538" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.99000999000999" /psig="0.99000999000999" /xcortree=866 /SigmaFactorBS="aatttctcgacaagggaagatgattactGACATTTttaagcc gggttgCCGCAAACTATGtgtattcaatatgaaaggagattattttgtgaaagttttg t" /listShort="lytH" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3187025 /Source="Nicolas_upshifts" /id="U2538" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.99000999000999" /psig="0.99000999000999" /xcortree=866 /SigmaFactorBS="aatttctcgacaagggaagatgattactGACATTTttaagcc gggttgCCGCAAACTATGtgtattcaatatgaaaggagattattttgtgaaagttttg t" /listShort="lytH" /GFF_Attribute="listLong" CDS 3187053..3188033 /gene="lytH" /locus_tag="BSU_32340" /old_locus_tag="BSU32340" /EC_number="3.4.-.-" /function="16.5: Explore" /function="16.13: Shape" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 12813075; Product type cp : cell process" /codon_start=1 /transl_table=11 /product="sporulation-specific L-Ala-D-Glu endopeptidase" /protein_id="NP_391114.2" /db_xref="EnsemblGenomes-Gn:BSU32340" /db_xref="EnsemblGenomes-Tr:CAB15224" /db_xref="GOA:O32130" /db_xref="InterPro:IPR011055" /db_xref="InterPro:IPR016047" /db_xref="SubtiList:BG13975" /db_xref="UniProtKB/Swiss-Prot:O32130" /translation="MKVLLSALLLLLFAFEPSASGKKLSDPVLSKRMELYHKIEAVTQ IPWYALAAVDQYEENVRSNRKDLPEKAGIISIYIPDDIWSGPENPNPKDDAPLSIKVF DGIGMDGDGDGKAEVSNDEDILYTFSQYLLSYGTDEDNIRIGLWNYYRRDQTVGIISE FMKLFKAYGHIDLGEHAFPLPIRTDYSYRSTWGDARGFGGRRIHEGTDIFAHYGLPVK STCYGVVEMKGWNRFGGWRIGIRDINNTYHYFAHLNGFAKGIKTGQIVEPGQVIGSVG SSGYGPPGTAGKFPPHLHYGMYKDNGRTEWSFDPYPHLRAWERYEYQKKK*" gene 3187053..3188033 /gene="lytH" /locus_tag="BSU_32340" /old_locus_tag="BSU32340" upshifts complement(3187131) /Source="Nicolas_upshifts" /id="U2539" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.832167832167832" /psig="0.873126873126873" /xcortree=2473 /SigmaFactorBS="aagggatCTGCgtcacagcttcgatttTATGATATAATTCCA TCCGTttcgacagcactggatctgaaagtttttttccagacgcagaaggctcaaatgc a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 complement(3187145..3187164) /Source="Nicolas_upshift_promotors" /id="U2539" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.832167832167832" /psig="0.873126873126873" /xcortree=2473 /SigmaFactorBS="aagggatCTGCgtcacagcttcgatttTATGATATAATTCCA TCCGTttcgacagcactggatctgaaagtttttttccagacgcagaaggctcaaatgc a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 complement(3187181..3187184) /Source="Nicolas_upshift_promotors" /id="U2539" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.832167832167832" /psig="0.873126873126873" /xcortree=2473 /SigmaFactorBS="aagggatCTGCgtcacagcttcgatttTATGATATAATTCCA TCCGTttcgacagcactggatctgaaagtttttttccagacgcagaaggctcaaatgc a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 3188025 /Source="Nicolas_upshifts" /id="D1679" /incds=0 /nref=35 /ntot=74 /MaxReadThrough="0.613989999999999" /MaxDrop="8.59238" /score="-3.31011906" /energy="-20" /TU="NA" /idTUdmin="U2538" /TUdmin=2 /isTUend="TRUE" CDS complement(3188061..3188825) /gene="fisB" /locus_tag="BSU_32350" /old_locus_tag="BSU32350" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:12662922, 23388828" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12662922, 23388828; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="protein required for membrane fission during spore formation" /protein_id="NP_391115.1" /db_xref="EnsemblGenomes-Gn:BSU32350" /db_xref="EnsemblGenomes-Tr:CAB15225" /db_xref="GOA:O32131" /db_xref="InterPro:IPR014197" /db_xref="SubtiList:BG13976" /db_xref="UniProtKB/Swiss-Prot:O32131" /translation="MPRYRGPFRKRGPLPFRYVMLLSVVFFILSTTVSLWMINGSIKP VLMDIGEMETKRIATEVIQDSIEDYMSDSENMKDMFQMNSDENGNLTTIDFNTQVVNS VKTKVTKQLQAHLKEMETHTGHSGASENIMINIPLGQVTGNSLLGNLGPKIPVRFNLI GDAFTDVKTKIKPYGINNALIDISIFVEIKVKVIIPFASKTAVVTNNVPVSIKAVQGE VPQFYNGSGGSGVTPSVQLPSSKENGADSKKEKSSK*" gene complement(3188061..3188825) /gene="fisB" /locus_tag="BSU_32350" /old_locus_tag="BSU32350" downshifts complement(3188077) /Source="Nicolas_upshifts" /id="D1680" /incds=0 /nref=74 /ntot=226 /MaxReadThrough="3.15258" /MaxDrop="6.53891" /score="23.5286262" /energy="-12.4" /TU="NA" /idTUdmin="U2540" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(3188839..3188857) /Source="Nicolas_upshift_promotors" /id="U2540" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1007 /SigmaFactorBS="gatgaaataaaataaattggccccggctaTTACTAtgtcccc tcttacaaGCATACATTGTGATATGTAaggggggattttcttgccaagatatcgcggc c" /listShort="yunB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3188847) /Source="Nicolas_upshifts" /id="U2540" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1007 /SigmaFactorBS="gatgaaataaaataaattggccccggctaTTACTAtgtcccc tcttacaaGCATACATTGTGATATGTAaggggggattttcttgccaagatatcgcggc c" /listShort="yunB" /GFF_Attribute="listLong" promotor_-35 complement(3188873..3188878) /Source="Nicolas_upshift_promotors" /id="U2540" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1007 /SigmaFactorBS="gatgaaataaaataaattggccccggctaTTACTAtgtcccc tcttacaaGCATACATTGTGATATGTAaggggggattttcttgccaagatatcgcggc c" /listShort="yunB" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3188898..3189203) /gene="yunC" /locus_tag="BSU_32360" /old_locus_tag="BSU32360" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_391116.1" /db_xref="EnsemblGenomes-Gn:BSU32360" /db_xref="EnsemblGenomes-Tr:CAB15226" /db_xref="InterPro:IPR014931" /db_xref="InterPro:IPR036493" /db_xref="SubtiList:BG13977" /db_xref="UniProtKB/Swiss-Prot:O32132" /translation="MVNLTPIMIEGQPFTAVTVKLPKTNFMAVANDHGYIMCGALDVA LLNEKLKERGIVAGRAVGVRTIDQLLDAPLESVTYAAEDLGIKVGMSGREALLKMMK* " gene complement(3188898..3189203) /gene="yunC" /locus_tag="BSU_32360" /old_locus_tag="BSU32360" downshifts complement(3188906) /Source="Nicolas_upshifts" /id="D1681" /incds=0 /nref=3 /ntot=128 /MaxReadThrough="5.18714" /MaxDrop="3.9347" /score="-2.65376612" /energy="-18.9" /TU="U2541,U2543,U2544" /idTUdmin="U2540" /TUdmin="-829" /isTUend="FALSE" promotor_-10 complement(3189217..3189236) /Source="Nicolas_upshift_promotors" /id="U2541" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.983016983016983" /psig="0.983016983016983" /xcortree=1347 /SigmaFactorBS="cgggatctgcttgcttggaagcttgcacaataaggcagtcag CCCACAACAagctgtgcccttcATCATAAAGTGATGAATGAAgggagtggttgacgtg g" /listShort="yunC, yunB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3189240) /Source="Nicolas_upshifts" /id="U2541" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.983016983016983" /psig="0.983016983016983" /xcortree=1347 /SigmaFactorBS="cgggatctgcttgcttggaagcttgcacaataaggcagtcag CCCACAACAagctgtgcccttcATCATAAAGTGATGAATGAAgggagtggttgacgtg g" /listShort="yunC, yunB" /GFF_Attribute="listLong" promotor_-35 complement(3189250..3189258) /Source="Nicolas_upshift_promotors" /id="U2541" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.983016983016983" /psig="0.983016983016983" /xcortree=1347 /SigmaFactorBS="cgggatctgcttgcttggaagcttgcacaataaggcagtcag CCCACAACAagctgtgcccttcATCATAAAGTGATGAATGAAgggagtggttgacgtg g" /listShort="yunC, yunB" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3189268..3190656) /gene="yunD" /locus_tag="BSU_32370" /old_locus_tag="BSU32370" /EC_number="3.1.-.-" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative nuclease/nucleotidase/phosphoesterase" /protein_id="NP_391117.1" /db_xref="EnsemblGenomes-Gn:BSU32370" /db_xref="EnsemblGenomes-Tr:CAB15227" /db_xref="GOA:O32133" /db_xref="InterPro:IPR006179" /db_xref="InterPro:IPR008334" /db_xref="InterPro:IPR011240" /db_xref="InterPro:IPR029052" /db_xref="InterPro:IPR036907" /db_xref="SubtiList:BG13978" /db_xref="UniProtKB/Swiss-Prot:O32133" /translation="MKEKLRLYHTNDLHSHFENWPKIVDYIEQKRKEHQSDGEETLVF DIGDHLDRFQFVTEATFGKANVDLLNRLHIDGAAIGNNEGITLPHEELAALYDHAEFP VIVSNLFDKNGNRPSWAVPYHIKSLKNGMSIAFLGVTVPYYPVYDKLGWTVTDALESI KETILEVKGQADIIVLLSHLGILDDQAVAEAVPEIDVILESHTHHLLEDGQVVNGVLL ASAEKYGHYVGCVEITVDSVQRSINSKTASVQNMAEWTGESAETKAFLNEKEREAEEK LSDAVAELAQDAEVKWFEESELPLLLAYALKEWCETDISMVNSGVILGPLKAGPVTKL DLHRICPHPINPVAVRLTGEELKETIVHAASEQMEQLRIKGLGFRGEVMGKMVYAGVE VETKRLDDGITHVTRITLNGEDIEKHKQYSVAVLDMFTLGKLFPLIRDAAEKEYFMPE FLRDLLAWKLAQ*" gene complement(3189268..3190656) /gene="yunD" /locus_tag="BSU_32370" /old_locus_tag="BSU32370" CDS complement(3190676..3191497) /gene="yunE" /locus_tag="BSU_32380" /old_locus_tag="BSU32380" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative transporter" /protein_id="NP_391118.1" /db_xref="EnsemblGenomes-Gn:BSU32380" /db_xref="EnsemblGenomes-Tr:CAB15228" /db_xref="GOA:O32134" /db_xref="InterPro:IPR002781" /db_xref="SubtiList:BG13979" /db_xref="UniProtKB/Swiss-Prot:O32134" /translation="MSFVILVVLGLIAGTVGSLIGLGGGIVIVPSLMFLSTVTQLFQD VTPQVAIGTSLLVIIFTGLSSTLAYIKYKTVDYKSGLIFFIGSGPGSMIGAYVSKLFN SNSFSVWFGIFMILISLSLMLKAKARPINKAHKGIIRTFQDDAGEPYTYSYQASVGIA IAFVVGFLGGLFGIGGGSLMVPAMMLLFLFPPKVAVATSMFIIFLSSMTGSVSHMISG HVNWLYALALVPGAWFGGKLGAAINRKMQTKTIVMIMRIVLILIGCQLIYEGIFS*" gene complement(3190676..3191497) /gene="yunE" /locus_tag="BSU_32380" /old_locus_tag="BSU32380" CDS complement(3191515..3192363) /gene="yunF" /locus_tag="BSU_32390" /old_locus_tag="BSU32390" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_391119.2" /db_xref="EnsemblGenomes-Gn:BSU32390" /db_xref="EnsemblGenomes-Tr:CAB15229" /db_xref="InterPro:IPR002763" /db_xref="InterPro:IPR036520" /db_xref="SubtiList:BG13980" /db_xref="UniProtKB/Swiss-Prot:O32135" /translation="MIYIGLTGWGDHDSIYPPKTASQKKLQAYSSHFPIVELDASFYA IQPARNNEKWVKETPETFQFIVKAYQGMTGHQRGEIPFDSKEEMFDAFKVSLTPYLHS NKLAMVLFQFPPWFDCKKENVAYLRWCKHQMGDIPCALEFRNRSWFSPPFYEQTLSFM KAEGWIHSVCDEPQIGEGSVPTVLRATDENKTLVRFHGRNKQGWMKPDGGKNWREVRY LYRYNQQELEDWKKHLNELQQQCKDVFVLFNNNSGGDAADNGKQMLELLDIEYSGLAP RQLDLF*" gene complement(3191515..3192363) /gene="yunF" /locus_tag="BSU_32390" /old_locus_tag="BSU32390" promotor_-35 3191882..3191887 /Source="Nicolas_upshift_promotors" /id="U2542" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.996003996003996" /psig="0.996003996003996" /xcortree=1206 /SigmaFactorBS="gacactgtgaatccagccttccgctTTCATAaatgaaagcgt ctgcTCATAAAATGGCGGCGAGAaccaggaacggtttctgaattcaagcgcgcaagga a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3191903..3191921 /Source="Nicolas_upshift_promotors" /id="U2542" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.996003996003996" /psig="0.996003996003996" /xcortree=1206 /SigmaFactorBS="gacactgtgaatccagccttccgctTTCATAaatgaaagcgt ctgcTCATAAAATGGCGGCGAGAaccaggaacggtttctgaattcaagcgcgcaagga a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3191917 /Source="Nicolas_upshifts" /id="U2542" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.996003996003996" /psig="0.996003996003996" /xcortree=1206 /SigmaFactorBS="gacactgtgaatccagccttccgctTTCATAaatgaaagcgt ctgcTCATAAAATGGCGGCGAGAaccaggaacggtttctgaattcaagcgcgcaagga a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" misc_feature complement(3192374..3192393) /Source="Nicolas_upshift_promotors" /id="U2543" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.915084915084915" /psig=1 /xcortree=1989 /SigmaFactorBS="gcgtgaggcattttcccgccatatgaacagcatttccgagga aacctgaaaacacgTGTGATAAACTGGAAGAGAGgtgaatgagtgtgatttatatcgg a" /listShort="yunF, yunE, yunD, yunC, yunB" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(3192389) /Source="Nicolas_upshifts" /id="U2543" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.915084915084915" /psig=1 /xcortree=1989 /SigmaFactorBS="gcgtgaggcattttcccgccatatgaacagcatttccgagga aacctgaaaacacgTGTGATAAACTGGAAGAGAGgtgaatgagtgtgatttatatcgg a" /listShort="yunF, yunE, yunD, yunC, yunB" /GFF_Attribute="listLong" CDS complement(3192401..3192748) /gene="yunG" /locus_tag="BSU_32400" /old_locus_tag="BSU32400" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_391120.1" /db_xref="EnsemblGenomes-Gn:BSU32400" /db_xref="EnsemblGenomes-Tr:CAB15230" /db_xref="SubtiList:BG13981" /db_xref="UniProtKB/Swiss-Prot:O32136" /translation="MEHVKYILKQSWSRHSSSKWTEECPSCGQCGVTALVIQDHFGGT IFKTRVDESWHFYNSINGVVYDFTSEQFQAPIEYQHIPSSREEAFLDTNEEQYQHLRE AFSRHMNSISEET*" gene complement(3192401..3192748) /gene="yunG" /locus_tag="BSU_32400" /old_locus_tag="BSU32400" promotor_-10 complement(3192761..3192780) /Source="Nicolas_upshift_promotors" /id="U2544" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.594405594405594" /psig="0.95904095904096" /xcortree=2362 /SigmaFactorBS="ggcggattttaccgccgggttttttgatttcctccgttctAG TTTTTaaaatctcatcaaCGTGGTATCTTTTTTTAAAGgaggcggaggcaatggagca t" /listShort="yunG, yunF, yunE, yunD, yunC, yunB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3192780) /Source="Nicolas_upshifts" /id="U2544" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.594405594405594" /psig="0.95904095904096" /xcortree=2362 /SigmaFactorBS="ggcggattttaccgccgggttttttgatttcctccgttctAG TTTTTaaaatctcatcaaCGTGGTATCTTTTTTTAAAGgaggcggaggcaatggagca t" /listShort="yunG, yunF, yunE, yunD, yunC, yunB" /GFF_Attribute="listLong" promotor_-35 complement(3192794..3192800) /Source="Nicolas_upshift_promotors" /id="U2544" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.594405594405594" /psig="0.95904095904096" /xcortree=2362 /SigmaFactorBS="ggcggattttaccgccgggttttttgatttcctccgttctAG TTTTTaaaatctcatcaaCGTGGTATCTTTTTTTAAAGgaggcggaggcaatggagca t" /listShort="yunG, yunF, yunE, yunD, yunC, yunB" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3192845..3194185) /gene="pucH" /locus_tag="BSU_32410" /old_locus_tag="BSU32410" /EC_number="3.5.2.5" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:11344136, 12029039" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11344136, 12029039; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="allantoinase" /protein_id="NP_391121.1" /db_xref="EnsemblGenomes-Gn:BSU32410" /db_xref="EnsemblGenomes-Tr:CAB15231" /db_xref="GOA:O32137" /db_xref="InterPro:IPR006680" /db_xref="InterPro:IPR011059" /db_xref="InterPro:IPR017593" /db_xref="InterPro:IPR032466" /db_xref="SubtiList:BG13982" /db_xref="UniProtKB/Swiss-Prot:O32137" /translation="MAYDMVIKGAKAVTPDGVIEADIVVQNGVIAEIGSDIEASGTEI IQADGKYVFPGVIDCHVHFNEPGREDWEGFETGSQMMAAGGCTTYFDMPLNCIPSTVT AEHLLAKAELGRQKSAVDFALWGGLVPGHIEDIRPMAEAGAIGFKAFLSKSGTDEFRS VDERTLLKGMAEIAAAGKILALHAESDAITSYLQMVLANKGKVDADAYAASRPEEAEV EAVYRTIQYAKVTGCPVHFVHISTAKAVRLIREAKQEGLDVSVETCPHYVLFSHDDLR QRGSVAKCAPPLRSRQSKETLIETLIAGDIDMVSSDHSPCRPSLKREDNMFLSWGGIS GGQFTLLGMLELALEHQIPFETIAEWTAAAPAKRFGLQKKGRLEAGCDADFVLVSMEP YTVTRESMFAKHKKSIYEGHTFPCSISATYSKGRCVYNDGEKVTEIDGALVVPS*" gene complement(3192845..3194185) /gene="pucH" /locus_tag="BSU_32410" /old_locus_tag="BSU32410" downshifts complement(3192873) /Source="Nicolas_upshifts" /id="D1682" /incds=0 /nref=5 /ntot=28 /MaxReadThrough="0.88847" /MaxDrop="3.89144" /score="36.6188375" /energy="-15.4" /TU="NA" /idTUdmin="U2540" /TUdmin="-4796" /isTUend="FALSE" downshifts complement(3193929) /Source="Nicolas_upshifts" /id="D1683" /incds=1 /nref=1 /ntot=7 /MaxReadThrough="3.38784" /MaxDrop="3.36547" /score="36.6188375" /energy="-15.4" /TU="NA" /idTUdmin="U2540" /TUdmin="-5852" /isTUend="FALSE" promotor_-35 3194242..3194248 /Source="Nicolas_upshift_promotors" /id="U2545" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.432567432567433" /psig="0.96103896103896" /xcortree=318 /SigmaFactorBS="cgattttccatgtcagtttatgtaacacaaccAGTTCTAttt tcaacagtttACTGCTACTATGATCGTATTacatcagcaaaaccgctagaattcctat t" /listShort="S1250, pucR" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3194262..3194281 /Source="Nicolas_upshift_promotors" /id="U2545" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.432567432567433" /psig="0.96103896103896" /xcortree=318 /SigmaFactorBS="cgattttccatgtcagtttatgtaacacaaccAGTTCTAttt tcaacagtttACTGCTACTATGATCGTATTacatcagcaaaaccgctagaattcctat t" /listShort="S1250, pucR" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-10 complement(3194264..3194282) /Source="Nicolas_upshift_promotors" /id="U2546" /multdbtbs="SigA" /comp="M3" /sig="SigEF" /pcomp="0.986013986013986" /psig="0.986013986013986" /xcortree=1026 /SigmaFactorBS="ataaaaacattggttaaggtgaataattttcaataggaATTC TAgcggttttgctgatgTAATACGATCATAGTAGCAgtaaactgttgaaaatagaact g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3194270 /Source="Nicolas_upshifts" /id="U2545" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.432567432567433" /psig="0.96103896103896" /xcortree=318 /SigmaFactorBS="cgattttccatgtcagtttatgtaacacaaccAGTTCTAttt tcaacagtttACTGCTACTATGATCGTATTacatcagcaaaaccgctagaattcctat t" /listShort="S1250, pucR" /GFF_Attribute="listLong" S_feature 3194271..3194359 /Source="Nicolas_S_feature" /locus_tag="new_3328673_3328761" /HighExp="BT, Cold, S0, LBGexp, S1, Lbtran, G150, T-1.40H, G180, Lbexp" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.961" /TUlongSig="NA" /TUlongPSig="NA" /label="S1250" upshifts complement(3194281) /Source="Nicolas_upshifts" /id="U2546" /multdbtbs="SigA" /comp="M3" /sig="SigEF" /pcomp="0.986013986013986" /psig="0.986013986013986" /xcortree=1026 /SigmaFactorBS="ataaaaacattggttaaggtgaataattttcaataggaATTC TAgcggttttgctgatgTAATACGATCATAGTAGCAgtaaactgttgaaaatagaact g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(3194298..3194303) /Source="Nicolas_upshift_promotors" /id="U2546" /multdbtbs="SigA" /comp="M3" /sig="SigEF" /pcomp="0.986013986013986" /psig="0.986013986013986" /xcortree=1026 /SigmaFactorBS="ataaaaacattggttaaggtgaataattttcaataggaATTC TAgcggttttgctgatgTAATACGATCATAGTAGCAgtaaactgttgaaaatagaact g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" CDS 3194360..3195955 /gene="pucR" /locus_tag="BSU_32420" /old_locus_tag="BSU32420" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:11344136, 12029039, 12374841" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11344136, 12029039, 12374841; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator of the purine degradation operon" /protein_id="NP_391122.1" /db_xref="EnsemblGenomes-Gn:BSU32420" /db_xref="EnsemblGenomes-Tr:CAB15232" /db_xref="GOA:O32138" /db_xref="InterPro:IPR012914" /db_xref="InterPro:IPR025736" /db_xref="InterPro:IPR028979" /db_xref="SubtiList:BG13983" /db_xref="UniProtKB/Swiss-Prot:O32138" /translation="MNILDVMKIPAFENANLIAGKAGGEREVQHVNMMDAPDIVDFLH KNELLVTTAYHLKDHPHQLSELIRQMAKRGCAGLGIKTKRYLEDIPKEIIELADSYAF PIIELPEHIRLGDIVNATLSHILDMRSNELQQAIYAHKKFTNHIMSGKGLQSLLKKVS DILQLPVLLLDQHAKMLSASHQISVETEKLKGTLNTVSGPFFTCFSTISDQKTYSVLP IYNHEKNCGYLLIPDMVQAGDKGLILTIEQAANVISFELLKENALKQFSRRARNEFFN NFIERTFSSDDEIKNRAKEFKLRWDQKYMCIAGKLDRNDESISFTENQLASDSVFEFL EGELSAFPFPPHFFMKGNVGIILIEATDSWSEMHASVISFLEQFQTQVSAQFKRTVSF GISNICQKLIDVPDAFTEASDALQSGHLSRSTAFIQVYHAKDVPELLRLLPVEDLKKF YNSTLQSLAEKQQEDQSLLHTLSVYLETHCQISETAKRLYVHRNTVIYRLEKCEELLG KSLKDPETTMRLRLALRMQRLIS*" gene 3194360..3195955 /gene="pucR" /locus_tag="BSU_32420" /old_locus_tag="BSU32420" CDS 3196100..3197449 /gene="pucJ" /locus_tag="BSU_32430" /old_locus_tag="BSU32430" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:11344136, 15849754, 16850406" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11344136, 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="uric acid permease" /protein_id="NP_391123.1" /db_xref="EnsemblGenomes-Gn:BSU32430" /db_xref="EnsemblGenomes-Tr:CAB15233" /db_xref="GOA:O32139" /db_xref="InterPro:IPR006042" /db_xref="InterPro:IPR006043" /db_xref="InterPro:IPR017588" /db_xref="SubtiList:BG13984" /db_xref="UniProtKB/Swiss-Prot:O32139" /translation="MKKRSFKVFTLSLQHVLAMYAGAILVPLLVGRALNVTTEQLSYL LAIDLLTCGVATLLQTLRGTYIGIGLPVMLGSSFVAVTPMIAIGSNYGIHAIYGSIIA AGVFIFLFARFFGKLTVLFPPVVTGTVVTLIGLSLVPTGVKNMAGGEKINGSANPEYG SLENLLLSVGVLVLILVLNRFLKGFARTLSVLIGIAAGTAAAAIMGKVSFSSVTEAPF FQIPKPFYFGAPAFEIGPILTMLIVGIVIIVESTGVFYAIGKICGRPLTDKDLVKGYR AEGIAILIGGLFNAFPYNTFAQNAGLLQLTKVKTRNIVVTAGCILVCLGLIPKIAALA SAVPAAVLGGATVVMFGMVIASGVKMLSTADLKNQYHLLTIACSIALGIGASTAPGIF AEFPAPIRILVSDGTITGSLTAIFLNLFFSLRDKKELTAQQTELPVLEHTLALEKEV* " gene 3196100..3197449 /gene="pucJ" /locus_tag="BSU_32430" /old_locus_tag="BSU32430" CDS 3197455..3198747 /gene="pucK" /locus_tag="BSU_32440" /old_locus_tag="BSU32440" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:11344136, 15849754, 16850406" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11344136, 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="uric acid permease subunit" /protein_id="NP_391124.1" /db_xref="EnsemblGenomes-Gn:BSU32440" /db_xref="EnsemblGenomes-Tr:CAB15234" /db_xref="GOA:O32140" /db_xref="InterPro:IPR006042" /db_xref="InterPro:IPR006043" /db_xref="InterPro:IPR017588" /db_xref="SubtiList:BG13985" /db_xref="UniProtKB/Swiss-Prot:O32140" /translation="MKEQHNALQLMMLGLQHMLAMYAGAILVPLIVGAAIGLNAGQLT YLIAIDLFMCGAATLLQLWRNRYFGIGLPVVLGCTFTAVGPMISIGSTYGVPAIYGAI IAAGLIVVLAAGFFGKLVRFFPPVVTGSVVMIIGISLIPTAMNNLAGGEGSKEFGSLD NVLLGFGVTAFILLLFYFFKGFIRSIAILLGLIAGTAAAYFMGKVDFSEVLEASWLHV PSLFYFGPPTFELPAVVTMLLVAIVSLVESTGVYFALADITNRRLSEKDLEKGYRAEG LAILLGGLFNAFPYTAFSQNVGIVQLSKMKSVNVIAITGIILVAIGLVPKAAALTTVI PTPVLGGAMIVMFGMVISYGIKMLSSVDLDSQGNLLIIASSVSLGLGATTVPALFSSL SGAASVLAGSGIVIGSLTAIALHAFFQTKQPNSADIKT*" gene 3197455..3198747 /gene="pucK" /locus_tag="BSU_32440" /old_locus_tag="BSU32440" CDS 3198760..3200244 /gene="pucL" /locus_tag="BSU_32450" /old_locus_tag="BSU32450" /EC_number="1.7.3.3" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:11344136, 12823818, 17567580, 20168977, 23760935, 28531234" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11344136, 12823818, 17567580, 20168977, 23760935, 28531234; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="urate oxidase with peroxide reductase N-terminaldomain" /protein_id="NP_391125.1" /db_xref="EnsemblGenomes-Gn:BSU32450" /db_xref="EnsemblGenomes-Tr:CAB15235" /db_xref="GOA:O32141" /db_xref="InterPro:IPR002042" /db_xref="InterPro:IPR017580" /db_xref="InterPro:IPR018020" /db_xref="InterPro:IPR019842" /db_xref="InterPro:IPR036778" /db_xref="SubtiList:BG13986" /db_xref="UniProtKB/Swiss-Prot:O32141" /translation="MFTMDDLNQMDTQTLTDTLGSIFEHSSWIAERSAALRPFSSLSD LHRKMTGIVKAADRETQLDLIKKHPRLGTKKTMSDDSVREQQNAGLGKLEQQEYEEFL MLNEHYYDRFGFPFILAVKGKTKQDIHQALLARLESERETEFQQALIEIYRIARFRLA DIITEKGETQMKRTMSYGKGNVFAYRTYLKPLTGVKQIPESSFAGRDNTVVGVDVTCE IGGEAFLPSFTDGDNTLVVATDSMKNFIQRHLASYEGTTTEGFLHYVAHRFLDTYSHM DTITLTGEDIPFEAMPAYEEKELSTSRLVFRRSRNERSRSVLKAERSGNTITITEQYS EIMDLQLVKVSGNSFVGFIRDEYTTLPEDGNRPLFVYLNISWQYENTNDSYASDPARY VAAEQVRDLASTVFHELETPSIQNLIYHIGCRILARFPQLTDVSFQSQNHTWDTVVEE IPGSKGKVYTEPRPPYGFQHFTVTREDAEKEKQKAAEKCRSLKA*" gene 3198760..3200244 /gene="pucL" /locus_tag="BSU_32450" /old_locus_tag="BSU32450" CDS 3200244..3200588 /gene="pucM" /locus_tag="BSU_32460" /old_locus_tag="BSU32460" /EC_number="3.5.2.17" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:11344136, 16098976, 16782815, 21795808" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11344136, 16098976, 16782815, 21795808; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="5-hydroxyisourate hydrolase; also uricase subunit" /protein_id="NP_391126.2" /db_xref="EnsemblGenomes-Gn:BSU32460" /db_xref="EnsemblGenomes-Tr:CAB15236" /db_xref="GOA:O32142" /db_xref="InterPro:IPR000895" /db_xref="InterPro:IPR014306" /db_xref="InterPro:IPR023416" /db_xref="InterPro:IPR023418" /db_xref="InterPro:IPR023419" /db_xref="InterPro:IPR036817" /db_xref="PDB:2H0E" /db_xref="PDB:2H0F" /db_xref="PDB:2H0J" /db_xref="SubtiList:BG13987" /db_xref="UniProtKB/Swiss-Prot:O32142" /translation="MGKLTTHILDLTCGKPAANVKIGLKRLGESIMKEVYTNNDGRVD VPLLAGEELMSGEYVMEFHAGDYFASKNMNAADQPFLTIVTVRFQLADPDAHYHIPLL LSPFGYQVYRGS*" gene 3200244..3200588 /gene="pucM" /locus_tag="BSU_32460" /old_locus_tag="BSU32460" promotor_-35 3200310..3200313 /Source="Nicolas_upshift_promotors" /id="U2547" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.95104895104895" /psig="0.975024975024975" /xcortree=2067 /SigmaFactorBS="ggcaaaccagcggcgaacgtaaaaattGGATtgaagcggctg ggcgaaAGTATTATGAAAGAGGTATAcactaacaatgacggcagggtcgatgtccctc t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3200331..3200350 /Source="Nicolas_upshift_promotors" /id="U2547" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.95104895104895" /psig="0.975024975024975" /xcortree=2067 /SigmaFactorBS="ggcaaaccagcggcgaacgtaaaaattGGATtgaagcggctg ggcgaaAGTATTATGAAAGAGGTATAcactaacaatgacggcagggtcgatgtccctc t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3200343 /Source="Nicolas_upshifts" /id="U2547" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.95104895104895" /psig="0.975024975024975" /xcortree=2067 /SigmaFactorBS="ggcaaaccagcggcgaacgtaaaaattGGATtgaagcggctg ggcgaaAGTATTATGAAAGAGGTATAcactaacaatgacggcagggtcgatgtccctc t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" downshifts 3200563 /Source="Nicolas_upshifts" /id="D1684" /incds=0 /nref=3 /ntot=90 /MaxReadThrough="1.80149" /MaxDrop="3.57243" /score="20.0549891" /energy="-14.2" /TU="NA" /idTUdmin="U2547" /TUdmin=0 /isTUend="TRUE" S_feature complement(3200604..3200991) /Source="Nicolas_S_feature" /locus_tag="new_3335006_3335393_c" /HighExp="BT, S8, T2.0H, LBGstat, Cold, Etha, Sw, T1.0H, T1.30H, T0.30H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="NA" /TUshortPSig="NA" /TUlongSig="NA" /TUlongPSig="NA" /label="S1251" promotor_-35 3200951..3200960 /Source="Nicolas_upshift_promotors" /id="U2548" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.976023976023976" /psig="0.976023976023976" /xcortree=1423 /SigmaFactorBS="agacaaaatattcattttttcttttttagacttaaATCTATG TCGaaaataatcgttGGCATATCTTATCCTATCTCcactaaaggaggtgacattatgg g" /listShort="yuzJ" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3200973..3200992 /Source="Nicolas_upshift_promotors" /id="U2548" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.976023976023976" /psig="0.976023976023976" /xcortree=1423 /SigmaFactorBS="agacaaaatattcattttttcttttttagacttaaATCTATG TCGaaaataatcgttGGCATATCTTATCCTATCTCcactaaaggaggtgacattatgg g" /listShort="yuzJ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3200976 /Source="Nicolas_upshifts" /id="U2548" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.976023976023976" /psig="0.976023976023976" /xcortree=1423 /SigmaFactorBS="agacaaaatattcattttttcttttttagacttaaATCTATG TCGaaaataatcgttGGCATATCTTATCCTATCTCcactaaaggaggtgacattatgg g" /listShort="yuzJ" /GFF_Attribute="listLong" ncRNA complement(3201012..3201143) /ncRNA_class="antisense_RNA" /gene="auzJ" /locus_tag="BSU_ncRNA_2" /product="putative antisense RNA for type I YuzJ toxin" /note="Evidence 3: Putative function from multiple computational evidences" CDS 3201012..3201143 /gene="yuzJ" /locus_tag="BSU_32469" /old_locus_tag="BSU32469" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 20156992, 20525796, 21670523; Product type f: factor" /codon_start=1 /transl_table=11 /product="putative type I toxin" /protein_id="YP_003097780.1" /db_xref="EnsemblGenomes-Gn:BSU32469" /db_xref="EnsemblGenomes-Tr:CAX52686" /db_xref="GOA:C0H3Q7" /db_xref="InterPro:IPR010070" /db_xref="UniProtKB/Swiss-Prot:C0H3Q7" /translation="MGFYNSGGYSGNSGYSNGFGSSFALIVVLFILLIIVGAAIFNY* " gene 3201012..3201143 /gene="yuzJ" /locus_tag="BSU_32469" /old_locus_tag="BSU32469" gene complement(3201012..3201143) /gene="auzJ" /locus_tag="BSU_ncRNA_2" S_feature 3201144..3201212 /Source="Nicolas_S_feature" /locus_tag="new_3335546_3335614" /HighExp="BT, B36, S8, G/S, B60, Pyr, Glucon, C30, S7, Mal" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="NA" /TUshortPSig="NA" /TUlongSig="NA" /TUlongPSig="NA" /label="S1252" downshifts 3201179 /Source="Nicolas_upshifts" /id="D1685" /incds=0 /nref=10 /ntot=25 /MaxReadThrough="0.61379" /MaxDrop="6.43101" /score="20.0549891" /energy="-14.2" /TU="NA" /idTUdmin="U2548" /TUdmin=0 /isTUend="TRUE" CDS complement(3201349..3201870) /gene="pucE" /locus_tag="BSU_32470" /old_locus_tag="BSU32470" /EC_number="1.17.1.4" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 9098051, 11344136, 18569337; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="xanthine dehydrogenase, iron-sulfur subunit" /protein_id="NP_391127.1" /db_xref="EnsemblGenomes-Gn:BSU32470" /db_xref="EnsemblGenomes-Tr:CAB15237" /db_xref="GOA:O32143" /db_xref="InterPro:IPR001041" /db_xref="InterPro:IPR002888" /db_xref="InterPro:IPR006058" /db_xref="InterPro:IPR012675" /db_xref="InterPro:IPR017611" /db_xref="InterPro:IPR036010" /db_xref="InterPro:IPR036884" /db_xref="SubtiList:BG13988" /db_xref="UniProtKB/Swiss-Prot:O32143" /translation="MDIKEAGPFPVKKEQFRMTVNGQAWEVAAVPTTHLSDLLRKEFQ LTGTKVSCGIGRCGACSILIDGKLANACMTMAYQADGHSITTIEGLQKEELDMCQTAF LEEGGFQCGYCTPGMIIALKALFRETPQPSDKDIEEGLAGNLCRCTGYGGIMRSACRI RRELNGGRRESGF*" gene complement(3201349..3201870) /gene="pucE" /locus_tag="BSU_32470" /old_locus_tag="BSU32470" CDS complement(3201861..3204098) /gene="pucD" /locus_tag="BSU_32480" /old_locus_tag="BSU32480" /EC_number="1.17.1.4" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 9098051, 11344136, 18569337; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="xanthine dehydrogenase, substrate and molybdenumcofactor subunit" /protein_id="NP_391128.1" /db_xref="EnsemblGenomes-Gn:BSU32480" /db_xref="EnsemblGenomes-Tr:CAB15238" /db_xref="GOA:O32144" /db_xref="InterPro:IPR000674" /db_xref="InterPro:IPR008274" /db_xref="InterPro:IPR017609" /db_xref="InterPro:IPR036856" /db_xref="InterPro:IPR037165" /db_xref="SubtiList:BG13989" /db_xref="UniProtKB/Swiss-Prot:O32144" /translation="MIINKPSRVRPDGRGKVTGELKYMTDLSFPGMLYGKVLRSAYPH AEIVSVCTIKAEKMEGVQAVVTHKDVPGLNRFGIVIPDQPVLCEDRVRYVGDAIAAVA AETEEIAEAALELIQVEYKELEVMDSPEKALRPNAQRLHEDGNILHRAFFSNGDVEEG FQASDTVFEETYELPRQMHTYMETEGGVAVPEDDGGFTMYAGTQHGYKDRFQLARIFD IPEEKIRIVSSPMGGSFGGKDELNIQPYAALLALKSGRPVKIHQTRKESVRSGIKRHP MKITIKTGADHSGNLLAHDVKIVADTGAYATLGPAVLDFSVEHAAGPYRIPNIRTEGI SVFTNNGVAGEFRGFGGNQITFALETHLDRLSGMLGIDPLELRRKNIRKPHDLGPLEH RIAPTDGAAQVLNAISKSPILKKTSRNCGYLQRGTGAAITMHGGGLGFGRMDAAGGRL SLSSEGKITASFGFEECGQGILAAIEQIVMEELGCAAEDISIVIGDTAKVPKSGSSTA SRGTSMVWHAIQRLKKPFLAQLKKRAAEWSGCSAENLIPGAAGLRDKNTKALVVTYKE LAEKGPLAEETAFDFPTTPDPVVGGHFLYSFGAAAVEVEVDLLTGDVKLIDCEHAIAA GPVVSPQGYRGQIEGGAAMALGYTLMEEAKMTDGRYAAENLDHYLIPGIKDVPDMKLI AIEDLMKGDVYGPRGVGEIGTIAITPAIVKAVHDAVGCWINKLPISREELLEAIDRKG LKQWT*" gene complement(3201861..3204098) /gene="pucD" /locus_tag="BSU_32480" /old_locus_tag="BSU32480" CDS complement(3204099..3204932) /gene="pucC" /locus_tag="BSU_32490" /old_locus_tag="BSU32490" /EC_number="1.17.1.4" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 9098051, 11344136, 18569337; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="xanthine dehydrogenase, FAD-binding subunit" /protein_id="NP_391129.1" /db_xref="EnsemblGenomes-Gn:BSU32490" /db_xref="EnsemblGenomes-Tr:CAB15239" /db_xref="GOA:O32145" /db_xref="InterPro:IPR002346" /db_xref="InterPro:IPR016166" /db_xref="InterPro:IPR016169" /db_xref="InterPro:IPR017612" /db_xref="InterPro:IPR036318" /db_xref="InterPro:IPR036683" /db_xref="SubtiList:BG13990" /db_xref="UniProtKB/Swiss-Prot:O32145" /translation="MNGQVTKARMNIQLWRPAALDEAYSLLEKLAPDVCAASGSTLLQ LQWDKGTLPKQHLVSLEGIDEMRGISTSDTHVSIGGLTSLNECRKNPLIKRALSCFSD AASAVAAPGIRSRATIGGNIASKIGDFIPLLLVLGAELIVYQKELIRLPLGAWLSEED FRTAIVTRVIIPRAEGERVFYHKLGRRQAFTGAAAVAAGRFLKDGSIRLAAGHADITP RRLLDSEAKWMAPGWDPHELYKTLIHELPFSSDVFMSAAYRKKAAANVIMAELMAEGG E*" gene complement(3204099..3204932) /gene="pucC" /locus_tag="BSU_32490" /old_locus_tag="BSU32490" CDS complement(3204929..3205546) /gene="pucB" /locus_tag="BSU_32500" /old_locus_tag="BSU32500" /EC_number="2.7.7.-" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 11344136, 21528011; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative molybdopterin cofactor synthesis cytidylyl transferase" /protein_id="NP_391130.2" /db_xref="EnsemblGenomes-Gn:BSU32500" /db_xref="EnsemblGenomes-Tr:CAB15240" /db_xref="GOA:O32146" /db_xref="InterPro:IPR017615" /db_xref="InterPro:IPR025877" /db_xref="InterPro:IPR029044" /db_xref="SubtiList:BG13991" /db_xref="UniProtKB/Swiss-Prot:O32146" /translation="MRSPYLIGVFLAAGKSRRMGQNKLALPLKGENIGSLSLKTALSS RLDHVLVVERTEHASLEWIGAPYHAPPFQKRWSLHVCQDAEKGQGHSVSSGVRKAESM GADGIVILLADQPQLSVDHLNALVALAPESFAVSSFLGAFTPPIYFSSTCFPYVKGLK GDEGARRLLKSGQLGAGAVLEAKDSGELDDIDTPEEYDMVRRAMS*" gene complement(3204929..3205546) /gene="pucB" /locus_tag="BSU_32500" /old_locus_tag="BSU32500" downshifts complement(3205038) /Source="Nicolas_upshifts" /id="D1686" /incds=1 /nref=3 /ntot=13 /MaxReadThrough="5.34639" /MaxDrop="3.22355" /score="-4.87239629" /energy="-9.9" /TU="U2549" /idTUdmin="U2549" /TUdmin="-3827" /isTUend="FALSE" CDS complement(3205543..3206535) /gene="pucA" /locus_tag="BSU_32510" /old_locus_tag="BSU32510" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:10217763, 11344136, 12029039" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10217763, 11344136, 12029039; Product type f: factor" /codon_start=1 /transl_table=11 /product="xanthine dehydrogenase molybdopterin recruitmentfactor" /protein_id="NP_391131.1" /db_xref="EnsemblGenomes-Gn:BSU32510" /db_xref="EnsemblGenomes-Tr:CAB15241" /db_xref="GOA:O32147" /db_xref="InterPro:IPR003777" /db_xref="InterPro:IPR027051" /db_xref="SubtiList:BG13992" /db_xref="UniProtKB/Swiss-Prot:O32147" /translation="MGNFHTMLDALLEDQEEAVLATIVQVEGSAYRKAGASMLFKKKG RRIGLLSGGCVEEDVFQRISALGDQLTSTLIPYDMRSEDDLSWGMGAGCNGIIHVHAE RITQEKRRHYEKVRDCLHSGKAVTSVIKIESSHYLFLTENGHFGNWPDAPLQDIQRTV STLHLPHFDQTTNMFIQRIEPKPRLILFGAGPDNVPLANLAADTGFSVIVTDWRPAYC TSSLFPKADQLITAFPEQMLSEFQFFPHDAAVVATHHYQHDQTIINFLFSQNLHYIGL LGSANRTKRLLSGKHPPSHFYSPVGLKIGAEGPEEIAVSVVAEIIQTRKRVAVV*" gene complement(3205543..3206535) /gene="pucA" /locus_tag="BSU_32510" /old_locus_tag="BSU32510" S_feature complement(3206536..3206622) /Source="Nicolas_S_feature" /locus_tag="new_3340938_3341024_c" /HighExp="BT, Cold, Sw, T-1.10H, S1, C30, S0, T-0.40H, T-3.40H, S2" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.607" /TUlongSig="NA" /TUlongPSig="NA" /label="S1253" promotor_-10 complement(3206600..3206619) /Source="Nicolas_upshift_promotors" /id="U2549" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.477522477522478" /psig="0.607392607392607" /xcortree=1437 /SigmaFactorBS="ttttacaaatcctctttctatgtgtttcattttctgacaaat caTGAGTCattttttcttccaTCGTCTATTCTTTATACAAGttacctataaaatcacg c" /listShort="S1253, pucA, pucB, pucC, pucD, pucE" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3206622) /Source="Nicolas_upshifts" /id="U2549" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.477522477522478" /psig="0.607392607392607" /xcortree=1437 /SigmaFactorBS="ttttacaaatcctctttctatgtgtttcattttctgacaaat caTGAGTCattttttcttccaTCGTCTATTCTTTATACAAGttacctataaaatcacg c" /listShort="S1253, pucA, pucB, pucC, pucD, pucE" /GFF_Attribute="listLong" promotor_-35 complement(3206633..3206638) /Source="Nicolas_upshift_promotors" /id="U2549" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.477522477522478" /psig="0.607392607392607" /xcortree=1437 /SigmaFactorBS="ttttacaaatcctctttctatgtgtttcattttctgacaaat caTGAGTCattttttcttccaTCGTCTATTCTTTATACAAGttacctataaaatcacg c" /listShort="S1253, pucA, pucB, pucC, pucD, pucE" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3206764..3208014) /gene="pucG" /locus_tag="BSU_32520" /old_locus_tag="BSU32520" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:11344136, 20852637, 28032445" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11344136, 20852637, 28032445; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="(S)-ureidoglycine-glyoxylate aminotransferase (PLP-dependent)" /protein_id="NP_391132.1" /db_xref="EnsemblGenomes-Gn:BSU32520" /db_xref="EnsemblGenomes-Tr:CAB15242" /db_xref="GOA:O32148" /db_xref="InterPro:IPR000192" /db_xref="InterPro:IPR015421" /db_xref="InterPro:IPR015422" /db_xref="InterPro:IPR015424" /db_xref="InterPro:IPR020578" /db_xref="InterPro:IPR024169" /db_xref="PDB:3ISL" /db_xref="SubtiList:BG13993" /db_xref="UniProtKB/Swiss-Prot:O32148" /translation="MSGRRELCTPLRTIMTPGPVEVDPRVLRVMSTPVVGQFDPAFTG IMNETMEMLRELFQTKNRWAYPIDGTSRAGIEAVLASVIEPEDDVLIPIYGRFGYLLT EIAERYGANVHMLECEWGTVFDPEDIIREIKKVKPKIVAMVHGETSTGRIHPLKAIGE ACRTEDALFIVDAVATIGGCEVKVDEWKIDAAIGGTQKCLSVPSGMAPITYNERVADV IAARKKVERGIATQADRAALSGNRPITSNYFDLSQLEDYWSERRLNHHTEATTMLYAL REGVRLVLEEGLETRFERHRHHEAALAAGIKAMGLRLFGDDSCKMPVVTCVEIPGGID GESVRDMLLAQFGIEIASSFGPLAGKIWRIGTMGYSCRKENVLFVLAGLEAVLLRHNA GIEAGKALQAALDVYENAGRQAAV*" gene complement(3206764..3208014) /gene="pucG" /locus_tag="BSU_32520" /old_locus_tag="BSU32520" CDS complement(3208031..3209269) /gene="pucF" /locus_tag="BSU_32530" /old_locus_tag="BSU32530" /EC_number="3.5.3.9" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 11344136, 17362992, 25020232; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="allantoate amidohydrolase" /protein_id="NP_391133.1" /db_xref="EnsemblGenomes-Gn:BSU32530" /db_xref="EnsemblGenomes-Tr:CAB15243" /db_xref="GOA:O32149" /db_xref="InterPro:IPR002933" /db_xref="InterPro:IPR010158" /db_xref="InterPro:IPR036264" /db_xref="SubtiList:BG13994" /db_xref="UniProtKB/Swiss-Prot:O32149" /translation="MEKQKLSVKNSITDYIEWLAQYGASADGGVTRLLYTKEWMDAQL AVKTEMSSFGLETRFDDVGNVFGRLSGTQSPDEVIVTGSHIDTVINGGKYDGAYGVLA AMLALKQLKETYGAPKKTLEAVSLCEEEGSRFPMTYWGSGNMTGVFSEQDAKEPRDES GVSLQTAMHESGFGKGVFQSAYRTDISAFVELHIEQGKTLEMSGRDLGIVTSIAGQRR YLVTLEGECNHAGTTSMKWRKDPLAASSRIIHELLLRSDELPDELRLTCGKITAEPNV ANVIPGRVQFSIDIRHQHQHVLEQFHQDMVALINGICLQKGIRAVIDEYMRIEPVPMD ERLKAAAFETALENGFSCEEMVSGAGHDAQMIGRRYPACMLFVPSRGGVSHSPKEYTS ARQLEIGVRALTDLLYKLAY*" gene complement(3208031..3209269) /gene="pucF" /locus_tag="BSU_32530" /old_locus_tag="BSU32530" CDS 3209492..3209629 /locus_tag="BSU_32539" /old_locus_tag="BSU32539" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_009514002.1" /translation="MNKLSWRGDVRGTDENRNAGSPQKQDLKIWKQEISASSKGTNLQ F*" gene 3209492..3209629 /locus_tag="BSU_32539" /old_locus_tag="BSU32539" promotor_-35 3209651..3209654 /Source="Nicolas_upshift_promotors" /id="U2550" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.921078921078921" /psig=1 /xcortree=463 /SigmaFactorBS="ggactaatttacaattttaatgaaaaatatacaaaatgacaC TTCtatcctttatttcaATTTTAGATAATAGATATGAtctgataaaaggagggcaagt g" /listShort="bsn" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3209669..3209688 /Source="Nicolas_upshift_promotors" /id="U2550" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.921078921078921" /psig=1 /xcortree=463 /SigmaFactorBS="ggactaatttacaattttaatgaaaaatatacaaaatgacaC TTCtatcctttatttcaATTTTAGATAATAGATATGAtctgataaaaggagggcaagt g" /listShort="bsn" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3209670 /Source="Nicolas_upshifts" /id="U2550" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.921078921078921" /psig=1 /xcortree=463 /SigmaFactorBS="ggactaatttacaattttaatgaaaaatatacaaaatgacaC TTCtatcctttatttcaATTTTAGATAATAGATATGAtctgataaaaggagggcaagt g" /listShort="bsn" /GFF_Attribute="listLong" CDS 3209711..3210577 /gene="bsnA" /locus_tag="BSU_32540" /old_locus_tag="BSU32540" /EC_number="3.1.-.-" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:1396690, 12490701, 12883447, 16291680, 25844442" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1396690, 12490701, 12883447, 16291680, 25844442; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="extracellular ribonuclease" /protein_id="NP_391134.1" /db_xref="EnsemblGenomes-Gn:BSU32540" /db_xref="EnsemblGenomes-Tr:CAB15244" /db_xref="GOA:O32150" /db_xref="InterPro:IPR007346" /db_xref="SubtiList:BG13995" /db_xref="UniProtKB/Swiss-Prot:O32150" /translation="MTKKAWFLPLVCVLLISGWLAPAASASAQTTLSLNDRLASSPSG TGSLLSLAAPAAPYADTDTYYEGAEGKTGDSLKSTLHRIISGHTMLSYSEVWNALKET DEDPRNPNNVILLYTNESRSKNLNGGNVGDWNREHVWAKSHGDFGTSKGPGTDIHHLR PADVQVNSARGNMDFDNGGTEYAKAPGNYYDGDSWEPRDDVKGDVARMLFYMAVRYEG DDGYPDLELNDKTGNGSAPYHGKQSVLLEWNKQDPVDDRERKRNEIIYEKYQHNRNPF IDHPEWADEIWP*" gene 3209711..3210577 /gene="bsnA" /locus_tag="BSU_32540" /old_locus_tag="BSU32540" downshifts 3210580 /Source="Nicolas_upshifts" /id="D1687" /incds=0 /nref=48 /ntot=190 /MaxReadThrough="0.45317" /MaxDrop="6.90997" /score="25.7790712" /energy="-15.5" /TU="NA" /idTUdmin="U2550" /TUdmin=8 /isTUend="TRUE" CDS complement(3210611..3211714) /gene="frlP" /locus_tag="BSU_32550" /old_locus_tag="BSU32550" /EC_number="3.6.3.-" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:23175651, 27501980" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 23175651, 27501980; Product type t: transporter" /codon_start=1 /transl_table=11 /product="fructose-amino acid ABC transporter (ATP-bindingsubunit)" /protein_id="NP_391135.1" /db_xref="EnsemblGenomes-Gn:BSU32550" /db_xref="EnsemblGenomes-Tr:CAB15245" /db_xref="GOA:O32151" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR008995" /db_xref="InterPro:IPR013611" /db_xref="InterPro:IPR017871" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG13996" /db_xref="UniProtKB/Swiss-Prot:O32151" /translation="MASLTFEHVKKSYHSQLTVKDFDLDVKDKELLVLVGPSGCGKST TLRMVAGLESISEGNLLIDGERVNDLPPKERDIAMVFQNYALYPHMTVFDNMAFGLKL RKMAKQEIAERVHAAARILEIEHLLKRKPKALSGGQRQRVALGRSIVREPKVFLMDEP LSNLDAKLRVTMRTEISKLHQRLEATIIYVTHDQTEAMTMGDRIVVMNEGEIQQVAKP HDIYHYPANLFVAGFIGSPGMNFLKGIIEQQHGELFFTNSSIRLHIPEEKAKRLKEKG YAGEQMIAGVRPEHITQMTGNDQLFDSVFQANVEVNENLGSELIVHVMAGDERLKVRL DGNTRIDAGDSIQLSVKMDHVVFFDAETEEAVY*" gene complement(3210611..3211714) /gene="frlP" /locus_tag="BSU_32550" /old_locus_tag="BSU32550" downshifts complement(3210626) /Source="Nicolas_upshifts" /id="D1688" /incds=0 /nref=57 /ntot=215 /MaxReadThrough="3.04361" /MaxDrop="6.06171" /score="29.1144499" /energy="-15.5" /TU="NA" /idTUdmin="U2553" /TUdmin=0 /isTUend="TRUE" S_feature complement(3211715..3212648) /Source="Nicolas_S_feature" /locus_tag="new_3346117_3347050_c" /HighExp="HiOs, T-5.40H, T5.0H, GM-0.1, S2, GM-0.2, GM 5, T-4.40H, T4.0H, SMM" /AntisenseName="frlR" /AntisenseCor="0.22682293682100099" /AntisenseRegPval="-3.8" /CDS_PredictionProba="NA" /TUshortSig="SigA, Sig-, SigA" /TUshortPSig="0.971, 0.456, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S1254" promotor_-35 3211752..3211759 /Source="Nicolas_upshift_promotors" /id="U2551" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.743256743256743" /psig="0.996003996003996" /xcortree=3177 /SigmaFactorBS="tccccctatcttttgacccgttatttcgtCACTGGAAacaac ttggtcttTCTGTTATTTTTAGAGTAATcgattcccatttttgctatatttctaaaat a" /listShort="frlR" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3211773..3211792 /Source="Nicolas_upshift_promotors" /id="U2551" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.743256743256743" /psig="0.996003996003996" /xcortree=3177 /SigmaFactorBS="tccccctatcttttgacccgttatttcgtCACTGGAAacaac ttggtcttTCTGTTATTTTTAGAGTAATcgattcccatttttgctatatttctaaaat a" /listShort="frlR" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3211783 /Source="Nicolas_upshifts" /id="U2551" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.743256743256743" /psig="0.996003996003996" /xcortree=3177 /SigmaFactorBS="tccccctatcttttgacccgttatttcgtCACTGGAAacaac ttggtcttTCTGTTATTTTTAGAGTAATcgattcccatttttgctatatttctaaaat a" /listShort="frlR" /GFF_Attribute="listLong" promotor_-35 3211834..3211840 /Source="Nicolas_upshift_promotors" /id="U2552" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.503496503496504" /psig="0.996003996003996" /xcortree=2434 /SigmaFactorBS="atcgattcccatttttgctatatttctaaaataaaaaatgta aATTTGTAttataacgtcataaTACATTATAATATAAATAATaggttaaaaggaggct a" /listShort="frlR" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 3211851 /Source="Nicolas_upshifts" /id="U2552" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.503496503496504" /psig="0.996003996003996" /xcortree=2434 /SigmaFactorBS="atcgattcccatttttgctatatttctaaaataaaaaatgta aATTTGTAttataacgtcataaTACATTATAATATAAATAATaggttaaaaggaggct a" /listShort="frlR" /GFF_Attribute="listLong" promotor_-10 3211855..3211874 /Source="Nicolas_upshift_promotors" /id="U2552" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.503496503496504" /psig="0.996003996003996" /xcortree=2434 /SigmaFactorBS="atcgattcccatttttgctatatttctaaaataaaaaatgta aATTTGTAttataacgtcataaTACATTATAATATAAATAATaggttaaaaggaggct a" /listShort="frlR" /GFF_Attribute="listLong" /label="promotor_-10" CDS 3211896..3212624 /gene="frlR" /locus_tag="BSU_32560" /old_locus_tag="BSU32560" /experiment="publication(s) with functional evidences, PMID:21347729, 21398478, 24673833" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 21347729, 21398478, 24673833; Product type r: regulator" /codon_start=1 /transl_table=11 /product="FrlR transcriptional regulator (GntR family)" /protein_id="NP_391136.3" /db_xref="EnsemblGenomes-Gn:BSU32560" /db_xref="EnsemblGenomes-Tr:CAB15246" /db_xref="GOA:O32152" /db_xref="InterPro:IPR000524" /db_xref="InterPro:IPR011663" /db_xref="InterPro:IPR028978" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="PDB:2IKK" /db_xref="SubtiList:BG13997" /db_xref="UniProtKB/Swiss-Prot:O32152" /translation="MLNNGSSTPLYIQLKQIITDDIKKGVYSPTAKLPTENELCTKYN VSRITVRKAILDLVEEGYLIRQQGKGTFVKSPKLKRELIAVNGYSEFMESTGKKPKHH VLSHDIIPASKPIAEKLQIQPESPVVELKRILYNDDQPLTFEVTHYPLDLFPGIDTFI ADGVSMHDILKQQYKVVPTHNTKLLNVVYAQQEESKYLDCDIGDALFEIDKTAFTSND QPIYCSLFLMHTNRVTFTINSPYT*" gene 3211896..3212624 /gene="frlR" /locus_tag="BSU_32560" /old_locus_tag="BSU32560" CDS complement(3212649..3213503) /gene="frlD" /locus_tag="BSU_32570" /old_locus_tag="BSU32570" /EC_number="2.7.1.-" /function="16.11: Scavenge (Catabolism)" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1b: Function from experimental evidences in the studied species; PubMedId: 14641112, 15556630, 16153181, 21347729, 21398478, 22720735; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="fructoselysine kinase" /protein_id="NP_391137.1" /db_xref="EnsemblGenomes-Gn:BSU32570" /db_xref="EnsemblGenomes-Tr:CAB15247" /db_xref="GOA:O32153" /db_xref="InterPro:IPR002173" /db_xref="InterPro:IPR011611" /db_xref="InterPro:IPR029056" /db_xref="SubtiList:BG13998" /db_xref="UniProtKB/Swiss-Prot:O32153" /translation="MKLIAVGDNVVDYYQDQETFYPGGNALNVAVLAKRLGHESSYIG IVGNDEAAAHLLNVLKLEQVNADYIRQAHGENGMAIVTLDEQGDRIFVRSNKGGIQSR LRLAFQEKDVSFISGHDLLHTSVYSRLENDLPQLCGLVPVSFDFSTNREDDYLRRVCP YVTYAFFSGSDLSESECGELAKTAHGYGAKMVCMTRGGQGAILSAGDRVYHQPIVEAD IIDTLGAGDSFIAGFLTAFCVKQDITYALRQAAETAAKTCGVYGAFGYGYPYRLEDGG SSEKTRIL*" gene complement(3212649..3213503) /gene="frlD" /locus_tag="BSU_32570" /old_locus_tag="BSU32570" misc_feature complement(3212836..3212855) /Source="Nicolas_upshift_promotors" /id="U2553" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.77022977022977" /psig="0.971028971028971" /xcortree=571 /SigmaFactorBS="aaggagcaatcctgtctgcgggtgatcgagtctatcatcagc cgattgtggaaGCTGATATAATAGATACACTtggagcgggagattcttttatagcagg c" /listShort="S1254, yurJ" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(3212848) /Source="Nicolas_upshifts" /id="U2553" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.77022977022977" /psig="0.971028971028971" /xcortree=571 /SigmaFactorBS="aaggagcaatcctgtctgcgggtgatcgagtctatcatcagc cgattgtggaaGCTGATATAATAGATACACTtggagcgggagattcttttatagcagg c" /listShort="S1254, yurJ" /GFF_Attribute="listLong" promotor_no_box complement(3213006..3213106) /Source="Nicolas_upshift_promotors" /id="U2554" /multdbtbs="-" /comp="M19" /sig="Sig-" /pcomp="0.320679320679321" /psig="0.455544455544456" /xcortree=1631 /SigmaFactorBS="ttccgcagctgtgcgggctggtcccggtctcatttgattttt caaccaatcgggaggatgattatttgaggagggtctgtccttatgtgacgtatgcgtt t" /listShort="S1254, yurJ" /GFF_Attribute="listLong" /label="promotor_no_box" upshifts complement(3213046) /Source="Nicolas_upshifts" /id="U2554" /multdbtbs="-" /comp="M19" /sig="Sig-" /pcomp="0.320679320679321" /psig="0.455544455544456" /xcortree=1631 /SigmaFactorBS="ttccgcagctgtgcgggctggtcccggtctcatttgattttt caaccaatcgggaggatgattatttgaggagggtctgtccttatgtgacgtatgcgtt t" /listShort="S1254, yurJ" /GFF_Attribute="listLong" CDS complement(3213517..3214419) /gene="frlM" /locus_tag="BSU_32580" /old_locus_tag="BSU32580" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2b: Function from indirect experimental evidences (e.g. phenotypes); PubMedId: 12618455, 15849754, 16850406, 15556630, 21347729; Product type t : transporter" /codon_start=1 /transl_table=11 /product="fructose-amino acid permease" /protein_id="NP_391138.1" /db_xref="EnsemblGenomes-Gn:BSU32580" /db_xref="EnsemblGenomes-Tr:CAB15248" /db_xref="GOA:O32154" /db_xref="InterPro:IPR000515" /db_xref="InterPro:IPR035906" /db_xref="SubtiList:BG13999" /db_xref="UniProtKB/Swiss-Prot:O32154" /translation="MLPQKKTDSFRLEPVPDQHIEVKDKPRRKWYIGETSVWVFLFLY LIAIAYPLLWMVMSAFKNSDDIFEHSWSLPSSWHPENFVSAWNQGISSYFMNSVIVTA LTCVITVFISAWAAYGLSRFEFKGKGFFLVLCLGGLMLTPQVSLVPLYSIIQSLGLYN TYWALILPYAAYRIPFTIILIRSYFLSISKELEEAAYLDGCTSFGVFFRIFLPMSVPI LVTSGILTAYHTWNEFMFAIIFIDDENLRTIPAGLMQFRDALQTDWGVLLAGLTISAA PIIILFLLMQKYFVRGIASGSVKG*" gene complement(3213517..3214419) /gene="frlM" /locus_tag="BSU_32580" /old_locus_tag="BSU32580" CDS complement(3214423..3215301) /gene="frlN" /locus_tag="BSU_32590" /old_locus_tag="BSU32590" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2b: Function from indirect experimental evidences (e.g. phenotypes); PubMedId: 12618455, 15849754, 16850406, 15556630, 21347729; Product type t : transporter" /codon_start=1 /transl_table=11 /product="fructose-amino acid permease" /protein_id="NP_391139.1" /db_xref="EnsemblGenomes-Gn:BSU32590" /db_xref="EnsemblGenomes-Tr:CAB15249" /db_xref="GOA:O32155" /db_xref="InterPro:IPR000515" /db_xref="InterPro:IPR035277" /db_xref="InterPro:IPR035906" /db_xref="SubtiList:BG14000" /db_xref="UniProtKB/Swiss-Prot:O32155" /translation="MVNQNKIIPYLFLVPALVFLLFVYIPIFENVFLSLFQWSSFSPE KTFIGLKNYVELFHDPVFYQALTNNVLYAVISIVCQVFGGLILAAVLEDKLVRKWSPF FRTVFFLPVVISMTVIALLFDFIYNPETGLLNQLLQAIGLDQLTRAWLGDDSTAMLSV IFVSQWQSVGYIAMLYIVSIQKIPDELYEAARLDGAGKIQQFFHITVPQTKEMSFVAV VMTLTGAFTVFNEPYILTGGGPGKASEVLSTFLYKSAFTKDMMGYASAIATVVLIITL ALSLMQMKFFKTGKEE*" gene complement(3214423..3215301) /gene="frlN" /locus_tag="BSU_32590" /old_locus_tag="BSU32590" CDS complement(3215359..3216627) /gene="frlO" /locus_tag="BSU_32600" /old_locus_tag="BSU32600" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2b: Function from indirect experimental evidences (e.g. phenotypes); PubMedId: 12618455, 21347729; Product type t: transporter" /codon_start=1 /transl_table=11 /product="fructose amino acid-binding lipoprotein" /protein_id="NP_391140.1" /db_xref="EnsemblGenomes-Gn:BSU32600" /db_xref="EnsemblGenomes-Tr:CAB15250" /db_xref="GOA:O32156" /db_xref="InterPro:IPR006059" /db_xref="SubtiList:BG14001" /db_xref="UniProtKB/Swiss-Prot:O32156" /translation="MKKMLLFLIIAAVSMLTIAGCSSQSSSADGKVTLKFFHRWPKEP EKSYFEEVVKEFEKDHPDIDIQIEAVLNDSYKDKIKVMLGTTSPPDIYFSWSDEFAFK FIRGNKALDLSSYYKNDTDWSSQLVQSQITPFTYENKQYGVPWQMDAKSFFYNKDIFQ KLNLDPPKTWDELIDVSKKLKEHGYTPISFGTKATWTISHYIGTLNQRMVDEKTREKD YNAKTGEFTDEGYVKALEKLQELMPYFNKHVNSVDHEYVRQQFKSGKSAMIYAETAEI KLVEPVNLGMFPFPEISGQKGSSEALTGAPEGFMISSRTKHPKEAMEFLQFLTSKRMG EKLVKDVGKYSAVQGTATEENATAIQREAVQHIVDAKSMVPWFDMDVDVEVADAYLTG VQQMLGGDMTPQQVMKAVQKAAKQVRASAE*" gene complement(3215359..3216627) /gene="frlO" /locus_tag="BSU_32600" /old_locus_tag="BSU32600" promotor_no_box 3216518..3216618 /Source="Nicolas_upshift_promotors" /id="U2555" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.99100899100899" /psig="0.000999000999001" /xcortree=21 /SigmaFactorBS="aaaaatttcaatgtcacctttccgtccgctgaactgctttgg ctcgaacagcctgcgatggtgagcatactgacagctgcaatgatcaagaacaacaaca t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_no_box" upshifts 3216578 /Source="Nicolas_upshifts" /id="U2555" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.99100899100899" /psig="0.000999000999001" /xcortree=21 /SigmaFactorBS="aaaaatttcaatgtcacctttccgtccgctgaactgctttgg ctcgaacagcctgcgatggtgagcatactgacagctgcaatgatcaagaacaacaaca t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" downshifts complement(3216698) /Source="Nicolas_upshifts" /id="D1689" /incds=0 /nref=21 /ntot=141 /MaxReadThrough="7.96763" /MaxDrop="4.994" /score="3.53212058" /energy="-13.8" /TU="U2557" /idTUdmin="U2558" /TUdmin=1210 /isTUend="FALSE" CDS complement(3216708..3217694) /gene="frlB" /locus_tag="BSU_32610" /old_locus_tag="BSU32610" /EC_number="3.5.-.-" /function="16.11: Scavenge (Catabolism)" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1b: Function from experimental evidences in the studied species; PubMedId: 12618455, 15556630, 16153181, 18083814, 21347729, 21398478, 22720735; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="fructosamine-6-P deglycase" /protein_id="NP_391141.1" /db_xref="EnsemblGenomes-Gn:BSU32610" /db_xref="EnsemblGenomes-Tr:CAB15251" /db_xref="GOA:O32157" /db_xref="InterPro:IPR001347" /db_xref="InterPro:IPR024713" /db_xref="InterPro:IPR035488" /db_xref="InterPro:IPR035490" /db_xref="PDB:3EUA" /db_xref="SubtiList:BG14002" /db_xref="UniProtKB/Swiss-Prot:O32157" /translation="MSQATAKVNREVQAFLQDLKGKTIDHVFFVACGGSSAIMYPSKY VFDRESKSINSDLYSANEFIQRNPVQLGEKSLVILCSHSGNTPETVKAAAFARGKGAL TIAMTFKPESPLAQEAQYVAQYDWGDEALAINTNYGVLYQIVFGTLQVLENNTKFEQA IEGLDQLQAVYEKALKQEADNAKQFAKAHEKESIIYTMASGANYGVAYSYSICILMEM QWIHSHAIHAGEYFHGPFEIIDESVPFIILLGLDETRPLEERALTFSKKYGKKLTVLD AASYDFTAIDDSVKGYLAPLVLNRVLRSYADELAEERNHPLSHRRYMWKVEY*" gene complement(3216708..3217694) /gene="frlB" /locus_tag="BSU_32610" /old_locus_tag="BSU32610" upshifts 3217641 /Source="Nicolas_upshifts" /id="U2556" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.972027972027972" /psig="0.002997002997003" /xcortree=22 /SigmaFactorBS="aatggcagaagaccctccgcatgcgacaaagaatacatgatc aatggttttccctttcaaatcCTGCAagaaagcttgaacctcacgatttacttttgct g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" misc_feature 3217644..3217648 /Source="Nicolas_upshift_promotors" /id="U2556" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.972027972027972" /psig="0.002997002997003" /xcortree=22 /SigmaFactorBS="aatggcagaagaccctccgcatgcgacaaagaatacatgatc aatggttttccctttcaaatcCTGCAagaaagcttgaacctcacgatttacttttgct g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" promotor_-10 complement(3217737..3217756) /Source="Nicolas_upshift_promotors" /id="U2557" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.998001998001998" /psig=1 /xcortree=2897 /SigmaFactorBS="cgaataaattattgagaaatttcagaaaataaTATTGACAat cctacccgcggaCTTTAATATAACAATATATAatgttatataacgttatataataaaa a" /listShort="frlB, frlO, frlN, frlM, frlD, S1254, yurJ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3217750) /Source="Nicolas_upshifts" /id="U2557" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.998001998001998" /psig=1 /xcortree=2897 /SigmaFactorBS="cgaataaattattgagaaatttcagaaaataaTATTGACAat cctacccgcggaCTTTAATATAACAATATATAatgttatataacgttatataataaaa a" /listShort="frlB, frlO, frlN, frlM, frlD, S1254, yurJ" /GFF_Attribute="listLong" promotor_-35 complement(3217771..3217778) /Source="Nicolas_upshift_promotors" /id="U2557" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.998001998001998" /psig=1 /xcortree=2897 /SigmaFactorBS="cgaataaattattgagaaatttcagaaaataaTATTGACAat cctacccgcggaCTTTAATATAACAATATATAatgttatataacgttatataataaaa a" /listShort="frlB, frlO, frlN, frlM, frlD, S1254, yurJ" /GFF_Attribute="listLong" /label="promotor_-35" downshifts complement(3217908) /Source="Nicolas_upshifts" /id="D1690" /incds=0 /nref=116 /ntot=274 /MaxReadThrough="0.87627" /MaxDrop="5.35981" /score="3.53212058" /energy="-13.8" /TU="NA" /idTUdmin="U2558" /TUdmin=0 /isTUend="TRUE" CDS complement(3217910..3218284) /gene="yurQ" /locus_tag="BSU_32620" /old_locus_tag="BSU32620" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative excinuclease" /protein_id="NP_391142.1" /db_xref="EnsemblGenomes-Gn:BSU32620" /db_xref="EnsemblGenomes-Tr:CAB15252" /db_xref="GOA:O32158" /db_xref="InterPro:IPR000305" /db_xref="InterPro:IPR014527" /db_xref="InterPro:IPR035901" /db_xref="SubtiList:BG14003" /db_xref="UniProtKB/Swiss-Prot:O32158" /translation="MIKIDIPAPNVTITERQQSANDNEPKIKPIHGFIDFHQIPRDKG GIFMFYNIHDELLFVGKARKLRQRIKKHFEDTVSPIKHHRDEVYKIEVCVVDDPMERE IYETYIINTQHSKYNIDKVFFK*" gene complement(3217910..3218284) /gene="yurQ" /locus_tag="BSU_32620" /old_locus_tag="BSU32620" upshifts complement(3218348) /Source="Nicolas_upshifts" /id="U2558" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.765234765234765" /psig="0.765234765234765" /xcortree=807 /SigmaFactorBS="tccagccggagcacttgcataaTAAGTAAgagcatgacaaac AAATATAATAAAgctgttctagcttttcttttctgtatgtgttagcatttatctttaa t" /listShort="yurQ" /GFF_Attribute="listLong" promotor_-10 complement(3218355..3218366) /Source="Nicolas_upshift_promotors" /id="U2558" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.765234765234765" /psig="0.765234765234765" /xcortree=807 /SigmaFactorBS="tccagccggagcacttgcataaTAAGTAAgagcatgacaaac AAATATAATAAAgctgttctagcttttcttttctgtatgtgttagcatttatctttaa t" /listShort="yurQ" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 complement(3218380..3218386) /Source="Nicolas_upshift_promotors" /id="U2558" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.765234765234765" /psig="0.765234765234765" /xcortree=807 /SigmaFactorBS="tccagccggagcacttgcataaTAAGTAAgagcatgacaaac AAATATAATAAAgctgttctagcttttcttttctgtatgtgttagcatttatctttaa t" /listShort="yurQ" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3218387..3219505) /gene="dadA" /locus_tag="BSU_32630" /old_locus_tag="BSU32630" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2b: Function from indirect experimental evidences (e.g. phenotypes); PubMedId: 13914427, 16245349, 22271930, 24826896; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="D-amino acid oxidase" /protein_id="NP_391143.1" /db_xref="EnsemblGenomes-Gn:BSU32630" /db_xref="EnsemblGenomes-Tr:CAB15253" /db_xref="GOA:O32159" /db_xref="InterPro:IPR006076" /db_xref="InterPro:IPR036188" /db_xref="SubtiList:BG14004" /db_xref="UniProtKB/Swiss-Prot:O32159" /translation="MKSYIIVGAGILGASTAYHLAKTGARVTVIDRKEPGQATDAAAG IVCPWLSQRRNQDWYQLAKGGARYYKDLIHQLEKDGESDTGYKRVGAISIHTDASKLD KMEERAYKRREDAPEIGDITRLSASETKKLFPILADGYESVHISGAARVNGRALCRSL LSAAEKRGATVIKGNASLLFENGTVTGVQTDTKQFAADAVIVTAGAWANEILKPLGIH FQVSFQKAQIMHFEMTDADTGSWPVVMPPSDQYILSFDNGRIVAGATHENDAGLDDLR VTAGGQHEVLSKALAVAPGLADAAAVETRVGFRPFTPGFLPVVGAVPNVQGLYAANGL GASGLTMGPFLGAELAKLVLGKQTELDLSPYDPAGALA*" gene complement(3218387..3219505) /gene="dadA" /locus_tag="BSU_32630" /old_locus_tag="BSU32630" promotor_-10 complement(3219530..3219549) /Source="Nicolas_upshift_promotors" /id="U2559" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.524475524475524" /psig="0.996003996003996" /xcortree=1879 /SigmaFactorBS="tcgcggtttttccacattagggcaaaaGGTCGAAggaaagca tttgaTTTGGTAAAATGAATAGACAttataatagaaaaggtgtttgcatatgaaatcg t" /listShort="yurR, yurQ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3219536) /Source="Nicolas_upshifts" /id="U2559" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.524475524475524" /psig="0.996003996003996" /xcortree=1879 /SigmaFactorBS="tcgcggtttttccacattagggcaaaaGGTCGAAggaaagca tttgaTTTGGTAAAATGAATAGACAttataatagaaaaggtgtttgcatatgaaatcg t" /listShort="yurR, yurQ" /GFF_Attribute="listLong" S_feature complement(3219538..3220148) /Source="Nicolas_S_feature" /locus_tag="new_3353940_3354550_c" /HighExp="G135, H2O2, G180, Paraq, G150, Oxctl, LBGexp, Salt, dia15, Diami" /AntisenseName="yurS" /AntisenseCor="-0.14245591415946501" /AntisenseRegPval="-1.7" /CDS_PredictionProba="0.95340499999999995" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="SigA, SigA" /TUlongPSig="1, 1" /label="S1255" promotor_-35 complement(3219563..3219569) /Source="Nicolas_upshift_promotors" /id="U2559" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.524475524475524" /psig="0.996003996003996" /xcortree=1879 /SigmaFactorBS="tcgcggtttttccacattagggcaaaaGGTCGAAggaaagca tttgaTTTGGTAAAATGAATAGACAttataatagaaaaggtgtttgcatatgaaatcg t" /listShort="yurR, yurQ" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 3219602..3219611 /Source="Nicolas_upshift_promotors" /id="U2560" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp="0.975024975024975" /psig="0.975024975024975" /xcortree=1408 /SigmaFactorBS="cttttgccctaatgtggaaaaaccgcgaagttcGTCCAATCT CtttactctcctatCGAATATCCTGTCACTATCAatagagaaaggatgataccatgag c" /listShort="sspG, yurS" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3219625..3219644 /Source="Nicolas_upshift_promotors" /id="U2560" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp="0.975024975024975" /psig="0.975024975024975" /xcortree=1408 /SigmaFactorBS="cttttgccctaatgtggaaaaaccgcgaagttcGTCCAATCT CtttactctcctatCGAATATCCTGTCACTATCAatagagaaaggatgataccatgag c" /listShort="sspG, yurS" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3219629 /Source="Nicolas_upshifts" /id="U2560" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp="0.975024975024975" /psig="0.975024975024975" /xcortree=1408 /SigmaFactorBS="cttttgccctaatgtggaaaaaccgcgaagttcGTCCAATCT CtttactctcctatCGAATATCCTGTCACTATCAatagagaaaggatgataccatgag c" /listShort="sspG, yurS" /GFF_Attribute="listLong" promotor_-10 complement(3219642..3219657) /Source="Nicolas_upshift_promotors" /id="U2561" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.966033966033966" /psig="0.026973026973027" /xcortree=688 /SigmaFactorBS="catcgcgtctgttttcttcattttcatgacgattttcgCTCA TggtatcATCCTTTCTCTATTGAtagtgacaggatattcgataggagagtaaagagat t" /listShort="yurR, yurQ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3219646) /Source="Nicolas_upshifts" /id="U2561" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.966033966033966" /psig="0.026973026973027" /xcortree=688 /SigmaFactorBS="catcgcgtctgttttcttcattttcatgacgattttcgCTCA TggtatcATCCTTTCTCTATTGAtagtgacaggatattcgataggagagtaaagagat t" /listShort="yurR, yurQ" /GFF_Attribute="listLong" promotor_-35 complement(3219664..3219668) /Source="Nicolas_upshift_promotors" /id="U2561" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.966033966033966" /psig="0.026973026973027" /xcortree=688 /SigmaFactorBS="catcgcgtctgttttcttcattttcatgacgattttcgCTCA TggtatcATCCTTTCTCTATTGAtagtgacaggatattcgataggagagtaaagagat t" /listShort="yurR, yurQ" /GFF_Attribute="listLong" /label="promotor_-35" CDS 3219664..3219810 /gene="sspG" /locus_tag="BSU_32640" /old_locus_tag="BSU32640" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:9852018" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9852018; Product type f : factor" /codon_start=1 /transl_table=11 /product="small acid-soluble spore protein" /protein_id="YP_054592.1" /db_xref="EnsemblGenomes-Gn:BSU32640" /db_xref="EnsemblGenomes-Tr:CAE01466" /db_xref="GOA:Q7WY59" /db_xref="SubtiList:BG14173" /db_xref="UniProtKB/Swiss-Prot:Q7WY59" /translation="MSENRHENEENRRDAAVAKVQNSGNAKVVVSVNTDQDQAQAQSQ DGED*" gene 3219664..3219810 /gene="sspG" /locus_tag="BSU_32640" /old_locus_tag="BSU32640" CDS 3219810..3220085 /gene="yurS" /locus_tag="BSU_32650" /old_locus_tag="BSU32650" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 9852018" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_391144.1" /db_xref="EnsemblGenomes-Gn:BSU32650" /db_xref="EnsemblGenomes-Tr:CAB15254" /db_xref="SubtiList:BG14005" /db_xref="UniProtKB/Swiss-Prot:O32160" /translation="MNENIIPLNRHTQEIPTTESVIKNSGNSEVHIDIHIDTMPIAFA ILCSALAAKQMTKEEFDMAYTQLREMNRENNSRSSVKQIINQETEEE*" gene 3219810..3220085 /gene="yurS" /locus_tag="BSU_32650" /old_locus_tag="BSU32650" upshifts complement(3219954) /Source="Nicolas_upshifts" /id="U2562" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.954045954045954" /psig="0.011988011988012" /xcortree=692 /SigmaFactorBS="ctcgcaattgagtataaGCCATatcgaattCCTCTTTTGTCA TCTgctttgcggctaatgcagagcataatatagcaaaagcaattggcattgtatcaat g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 complement(3219970..3219984) /Source="Nicolas_upshift_promotors" /id="U2562" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.954045954045954" /psig="0.011988011988012" /xcortree=692 /SigmaFactorBS="ctcgcaattgagtataaGCCATatcgaattCCTCTTTTGTCA TCTgctttgcggctaatgcagagcataatatagcaaaagcaattggcattgtatcaat g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 complement(3219993..3219997) /Source="Nicolas_upshift_promotors" /id="U2562" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.954045954045954" /psig="0.011988011988012" /xcortree=692 /SigmaFactorBS="ctcgcaattgagtataaGCCATatcgaattCCTCTTTTGTCA TCTgctttgcggctaatgcagagcataatatagcaaaagcaattggcattgtatcaat g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 3220065 /Source="Nicolas_upshifts" /id="D1691" /incds=0 /nref=36 /ntot=86 /MaxReadThrough="1.84089" /MaxDrop="7.4989" /score="15.0184762" /energy="-11" /TU="NA" /idTUdmin="U2560" /TUdmin="-11" /isTUend="TRUE" CDS complement(3220149..3220532) /gene="glxB" /locus_tag="BSU_32660" /old_locus_tag="BSU32660" /function="16.11: Scavenge (Catabolism)" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:10882093, 24330391" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10882093, 24330391; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="methylglyoxalase; lactoylbacillithiol lyase" /protein_id="NP_391145.1" /db_xref="EnsemblGenomes-Gn:BSU32660" /db_xref="EnsemblGenomes-Tr:CAB15255" /db_xref="GOA:O32161" /db_xref="InterPro:IPR004360" /db_xref="InterPro:IPR029068" /db_xref="SubtiList:BG14006" /db_xref="UniProtKB/Swiss-Prot:O32161" /translation="MKIVVTSIFVQDQDMALEFYTEKLGFIKKEDVPMGKFRWITLVS PDDQDGTELLLEPNEHPAAKEYQKKIFSEGLPATMFGVADIQKEYNRLKEKGVTFTTE PTKMGEVTIAVFDDTCGNLIQIVQK*" gene complement(3220149..3220532) /gene="glxB" /locus_tag="BSU_32660" /old_locus_tag="BSU32660" S_feature complement(3220533..3220642) /Source="Nicolas_S_feature" /locus_tag="new_3354935_3355044_c" /HighExp="Salt, G180, H2O2, Paraq, G135, G150, LBGexp, LBGstat, dia15, Oxctl" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="SigA, SigA" /TUlongPSig="1, 1" /label="S1256" CDS complement(3220643..3220921) /gene="yuzN" /locus_tag="BSU_32669" /old_locus_tag="BSU32669" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative transcriptional regulator" /protein_id="YP_003097781.1" /db_xref="EnsemblGenomes-Gn:BSU32669" /db_xref="EnsemblGenomes-Tr:CAX52687" /db_xref="GOA:C0H3Q8" /db_xref="InterPro:IPR001845" /db_xref="InterPro:IPR011991" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="UniProtKB/Swiss-Prot:C0H3Q8" /translation="MNGNKDAIFKALGDSTRRLILDELSERNELTLYELTIRLITKYD LSITRQAIAKHLSVLEDAGLVTSKRKGKYRVLIFNNEPLKNLLKGWIE*" gene complement(3220643..3220921) /gene="yuzN" /locus_tag="BSU_32669" /old_locus_tag="BSU32669" promotor_-10 complement(3220919..3220938) /Source="Nicolas_upshift_promotors" /id="U2563" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.846153846153846" /psig=1 /xcortree=2701 /SigmaFactorBS="ggataggttcagtttctatatcacgcaaccatacagttgctt aTACTTGACatgcaactaatgggTTGCTTATACTCAATATATGaatgggaacaaagac g" /listShort="yuzN, S1256, yurT, S1255, yurR, yurQ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3220943) /Source="Nicolas_upshifts" /id="U2563" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.846153846153846" /psig=1 /xcortree=2701 /SigmaFactorBS="ggataggttcagtttctatatcacgcaaccatacagttgctt aTACTTGACatgcaactaatgggTTGCTTATACTCAATATATGaatgggaacaaagac g" /listShort="yuzN, S1256, yurT, S1255, yurR, yurQ" /GFF_Attribute="listLong" promotor_-35 complement(3220953..3220960) /Source="Nicolas_upshift_promotors" /id="U2563" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.846153846153846" /psig=1 /xcortree=2701 /SigmaFactorBS="ggataggttcagtttctatatcacgcaaccatacagttgctt aTACTTGACatgcaactaatgggTTGCTTATACTCAATATATGaatgggaacaaagac g" /listShort="yuzN, S1256, yurT, S1255, yurR, yurQ" /GFF_Attribute="listLong" /label="promotor_-35" S_feature complement(3221084..3221190) /Source="Nicolas_S_feature" /locus_tag="new_3355486_3355592_c" /HighExp="Sw, BI, LPhT, C90, BC, M0t45, Gly, Cold, H2O2, M40t45" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA, SigA" /TUshortPSig="1, 1, 0.994" /TUlongSig="SigGF" /TUlongPSig="0.999" /label="S1257" downshifts complement(3221127) /Source="Nicolas_upshifts" /id="D1692" /incds=0 /nref=189 /ntot=303 /MaxReadThrough="3.22318" /MaxDrop="7.82118" /score="0.760415296" /energy="-10.1" /TU="U2564" /idTUdmin="U2565" /TUdmin="-7" /isTUend="TRUE" CDS complement(3221191..3222588) /gene="sufB" /locus_tag="BSU_32670" /old_locus_tag="BSU32670" /function="16.2: Construct biomass (Anabolism)" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:12682299, 16109955, 16431905, 16621837, 20097860" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12682299, 16109955, 16431905, 16621837, 20097860; Product type f: factor" /codon_start=1 /transl_table=11 /product="FeS cluster formation scaffold protein" /protein_id="NP_391146.1" /db_xref="EnsemblGenomes-Gn:BSU32670" /db_xref="EnsemblGenomes-Tr:CAB15256" /db_xref="GOA:O32162" /db_xref="InterPro:IPR000825" /db_xref="InterPro:IPR010231" /db_xref="SubtiList:BG14007" /db_xref="UniProtKB/Swiss-Prot:O32162" /translation="MAKKMPDIGEYKYGFHDKDVSIFRSERGLTKEIVEEISRMKEEP QWMLDFRLKSLEHFYNMPMPQWGGDLNSLNFDEITYYVKPSERSERSWDEVPEEIKQT FDKLGIPEAEQKYLAGVSAQYESEVVYHNMKEDLEAQGIVFKDTDSALKENEDIFREH WAKVIPPTDNKFAALNSAVWSGGSFIYVPKGVKVETPLQAYFRINSENMGQFERTLII VDEEASVHYVEGCTAPVYTTNSLHSAVVEIIVKKGGYCRYTTIQNWANNVYNLVTKRT VCEENATMEWIDGNIGSKLTMKYPACILKGEGARGMTLSIALAGKGQHQDAGAKMIHL APNTSSTIVSKSISKQGGKVTYRGIVHFGRKAEGARSNIECDTLIMDNKSTSDTIPYN EILNDNISLEHEAKVSKVSEEQLFYLMSRGISEEEATEMIVMGFIEPFTKELPMEYAV EMNRLIKFEMEGSIG*" gene complement(3221191..3222588) /gene="sufB" /locus_tag="BSU_32670" /old_locus_tag="BSU32670" downshifts 3222386 /Source="Nicolas_upshifts" /id="D1693" /incds=1 /nref=1 /ntot=150 /MaxReadThrough="2.66718" /MaxDrop="3.75483" /score="-4.89805724" /energy="-5" /TU="NA" /idTUdmin="U2560" /TUdmin=2310 /isTUend="FALSE" CDS complement(3222609..3223052) /gene="sufU" /locus_tag="BSU_32680" /old_locus_tag="BSU32680" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:12682299, 16877383, 20097860, 21236255, 24321018, 22720735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12682299, 16877383, 20097860, 21236255, 24321018, 22720735; Product type f : factor" /codon_start=1 /transl_table=11 /product="iron-sulfur cluster assembly sulfur-transfer protein (Zn(2+)-dependent)" /protein_id="NP_391147.1" /db_xref="EnsemblGenomes-Gn:BSU32680" /db_xref="EnsemblGenomes-Tr:CAB15257" /db_xref="GOA:O32163" /db_xref="InterPro:IPR002871" /db_xref="PDB:1XJS" /db_xref="PDB:2AZH" /db_xref="SubtiList:BG14008" /db_xref="UniProtKB/Swiss-Prot:O32163" /translation="MSFNANLDTLYRQVIMDHYKNPRNKGVLNDSIVVDMNNPTCGDR IRLTMKLDGDIVEDAKFEGEGCSISMASASMMTQAIKGKDIETALSMSKIFSDMMQGK EYDDSIDLGDIEALQGVSKFPARIKCATLSWKALEKGVAKEEGGN*" gene complement(3222609..3223052) /gene="sufU" /locus_tag="BSU_32680" /old_locus_tag="BSU32680" CDS complement(3223042..3224262) /gene="sufS" /locus_tag="BSU_32690" /old_locus_tag="BSU32690" /EC_number="2.8.1.7" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:12682299, 12876288, 14644425, 15901727, 20822158, 21236255, 27382962" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12682299, 12876288, 14644425, 15901727, 20822158, 21236255, 27382962; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="cysteine desulfurase" /protein_id="NP_391148.1" /db_xref="EnsemblGenomes-Gn:BSU32690" /db_xref="EnsemblGenomes-Tr:CAB15258" /db_xref="GOA:O32164" /db_xref="InterPro:IPR000192" /db_xref="InterPro:IPR010970" /db_xref="InterPro:IPR015421" /db_xref="InterPro:IPR015422" /db_xref="InterPro:IPR015424" /db_xref="InterPro:IPR016454" /db_xref="InterPro:IPR020578" /db_xref="PDB:5J8Q" /db_xref="SubtiList:BG14009" /db_xref="UniProtKB/Swiss-Prot:O32164" /translation="MNITDIREQFPILHQQVNGHDLVYLDSAATSQKPRAVIETLDKY YNQYNSNVHRGVHTLGTRATDGYEGAREKVRKFINAKSMAEIIFTKGTTTSLNMVALS YARANLKPGDEVVITYMEHHANIIPWQQAVKATGATLKYIPLQEDGTISLEDVRETVT SNTKIVAVSHVSNVLGTVNPIKEMAKIAHDNGAVIVVDGAQSTPHMKIDVQDLDCDFF ALSSHKMCGPTGVGVLYGKKALLENMEPAEFGGEMIDFVGLYESTWKELPWKFEAGTP IIAGAIGLGAAIDFLEEIGLDEISRHEHKLAAYALERFRQLDGVTVYGPEERAGLVTF NLDDVHPHDVATVLDAEGIAVRAGHHCAQPLMKWLDVTATARASFYLYNTEEEIDKLV EALQKTKEYFTNVF*" gene complement(3223042..3224262) /gene="sufS" /locus_tag="BSU_32690" /old_locus_tag="BSU32690" CDS complement(3224262..3225575) /gene="sufD" /locus_tag="BSU_32700" /old_locus_tag="BSU32700" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 12682299, 16109955, 16431905, 16621837, 19187533, 20097860, 28839209; Product type f: factor" /codon_start=1 /transl_table=11 /product="Fe-S cluster assembly protein SufD" /protein_id="NP_391149.1" /db_xref="EnsemblGenomes-Gn:BSU32700" /db_xref="EnsemblGenomes-Tr:CAB15259" /db_xref="GOA:O32165" /db_xref="InterPro:IPR000825" /db_xref="InterPro:IPR011542" /db_xref="SubtiList:BG14010" /db_xref="UniProtKB/Swiss-Prot:O32165" /translation="MTLGTKLSVDQEYLKSFSEKHQEPAWLKNLRLQALEQAEDLPMP KPDKTKITNWNFTNFAKHTVDNEPLSSLEDLTDEVKALIDIENEDKTLYVQRDQTPAH LSLSQELKDKGVIFTDILTAAREHSDLVEKYFMKDGVKVDEHKLTALHAALVNGGAFL YVPKNVQVETPVQAVYVHESNDTALFNHVLIVAEDHSSVTYVENYISTVNPKDAVFNI ISEVITGDNASVTYGAVDNLSSGVTTYVNRRGAARGRDSKIEWALGLMNDGDTISENT TNLYGDGTYGDTKTVVVGRGEQTENFTTQIIHFGKASEGYILKHGVMKDSASSIFNGI GKIEHGASKANAEQESRVLMLSEKARGDANPILLIDEDDVTAGHAASVGRVDPIQLYY LMSRGIPKEEAERLVIYGFLAPVVNELPIEGVKKQLVSVIERKVK*" gene complement(3224262..3225575) /gene="sufD" /locus_tag="BSU_32700" /old_locus_tag="BSU32700" CDS complement(3225593..3226378) /gene="sufC" /locus_tag="BSU_32710" /old_locus_tag="BSU32710" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:12682299, 16431905, 20097860, 28839209" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12682299, 16431905, 20097860, 28839209; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="sulfur mobilizing ABC protein, ATPase" /protein_id="NP_391150.1" /db_xref="EnsemblGenomes-Gn:BSU32710" /db_xref="EnsemblGenomes-Tr:CAB15260" /db_xref="GOA:P80866" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR010230" /db_xref="InterPro:IPR017871" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG14011" /db_xref="UniProtKB/Swiss-Prot:P80866" /translation="MAASTLTIKDLHVEIEGKEILKGVNLEIKGGEFHAVMGPNGTGK STLSAAIMGHPKYEVTKGSITLDGKDVLEMEVDERAQAGLFLAMQYPSEISGVTNADF LRSAINARREEGDEISLMKFIRKMDENMEFLEMDPEMAQRYLNEGFSGGEKKRNEILQ LMMIEPKIAILDEIDSGLDIDALKVVSKGINKMRSENFGCLMITHYQRLLNYITPDVV HVMMQGRVVKSGGAELAQRLEAEGYDWIKQELGIEDETVGQEA*" gene complement(3225593..3226378) /gene="sufC" /locus_tag="BSU_32710" /old_locus_tag="BSU32710" promotor_-10 complement(3226422..3226441) /Source="Nicolas_upshift_promotors" /id="U2564" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.658341658341658" /psig=1 /xcortree=2086 /SigmaFactorBS="gaatgtgcaaggcacgataaaAAGTTGTAtttacttttcatt TGTTATAAAATTAGAATGAGaataaaatgagaataatgattatatatttttggaggta t" /listShort="sufC, sufD, sufS, iscU, sufB, S1257" /listLong="yuzN, S1256, yurT, S1255, yurR, yurQ" /label="promotor_-10" upshifts complement(3226423) /Source="Nicolas_upshifts" /id="U2564" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.658341658341658" /psig=1 /xcortree=2086 /SigmaFactorBS="gaatgtgcaaggcacgataaaAAGTTGTAtttacttttcatt TGTTATAAAATTAGAATGAGaataaaatgagaataatgattatatatttttggaggta t" /listShort="sufC, sufD, sufS, iscU, sufB, S1257" /listLong="yuzN, S1256, yurT, S1255, yurR, yurQ" promotor_-35 complement(3226455..3226462) /Source="Nicolas_upshift_promotors" /id="U2564" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.658341658341658" /psig=1 /xcortree=2086 /SigmaFactorBS="gaatgtgcaaggcacgataaaAAGTTGTAtttacttttcatt TGTTATAAAATTAGAATGAGaataaaatgagaataatgattatatatttttggaggta t" /listShort="sufC, sufD, sufS, iscU, sufB, S1257" /listLong="yuzN, S1256, yurT, S1255, yurR, yurQ" /label="promotor_-35" promotor_-10 complement(3226479..3226498) /Source="Nicolas_upshift_promotors" /id="U2565" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.829170829170829" /psig=1 /xcortree=2486 /SigmaFactorBS="gtgggaatccactctttttctttttcaatcGCTTTaataaag tgctgatcTTTGTTAAACTTGAGGAATGtgcaaggcacgataaaaagttgtatttact t" /listShort="sufC, sufD, sufS, iscU, sufB, S1257" /listLong="yuzN, S1256, yurT, S1255, yurR, yurQ" /label="promotor_-10" upshifts complement(3226488) /Source="Nicolas_upshifts" /id="U2565" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.829170829170829" /psig=1 /xcortree=2486 /SigmaFactorBS="gtgggaatccactctttttctttttcaatcGCTTTaataaag tgctgatcTTTGTTAAACTTGAGGAATGtgcaaggcacgataaaaagttgtatttact t" /listShort="sufC, sufD, sufS, iscU, sufB, S1257" /listLong="yuzN, S1256, yurT, S1255, yurR, yurQ" S_feature complement(3226490..3226571) /Source="Nicolas_S_feature" /locus_tag="new_3360892_3360973_c" /HighExp="Salt, HiOs, B60, LoTm, T1.0H, Gly, T2.0H, C30, Etha, T3.30H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigGF" /TUshortPSig="0.994, 0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S1258" promotor_-35 complement(3226514..3226518) /Source="Nicolas_upshift_promotors" /id="U2565" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.829170829170829" /psig=1 /xcortree=2486 /SigmaFactorBS="gtgggaatccactctttttctttttcaatcGCTTTaataaag tgctgatcTTTGTTAAACTTGAGGAATGtgcaaggcacgataaaaagttgtatttact t" /listShort="sufC, sufD, sufS, iscU, sufB, S1257" /listLong="yuzN, S1256, yurT, S1255, yurR, yurQ" /label="promotor_-35" misc_RNA complement(3226535..3226782) /gene="bsrI" /locus_tag="BSU_misc_RNA_84" /product="small regulatory RNA or messenger RNA" /experiment="publication(s) with functional evidences, PMID:18948176" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 18948176; Product type n: RNA" gene complement(3226535..3226782) /gene="bsrI" /locus_tag="BSU_misc_RNA_84" CDS complement(3226572..3226709) /gene="yuzK" /locus_tag="BSU_32719" /old_locus_tag="BSU32719" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type f: factor" /codon_start=1 /transl_table=11 /product="putative toxin of a toxin antitoxin system" /protein_id="YP_003097782.1" /db_xref="EnsemblGenomes-Gn:BSU32719" /db_xref="EnsemblGenomes-Tr:CAX52688" /db_xref="UniProtKB/Swiss-Prot:C0H3Q9" /translation="MEKAMQLSHGIGYEEYGRRLETRMKVERQRELDYEKSKRISAGA Y*" gene complement(3226572..3226709) /gene="yuzK" /locus_tag="BSU_32719" /old_locus_tag="BSU32719" S_feature complement(3226710..3226794) /Source="Nicolas_S_feature" /locus_tag="new_3361112_3361196_c" /HighExp="HiOs, Salt, B60, S5, T1.0H, S8, HiTm, S7, T1.30H, Etha" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.63415999999999995" /TUshortSig="SigA, SigGF" /TUshortPSig="0.994, 0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S1259" promotor_-10 complement(3226778..3226797) /Source="Nicolas_upshift_promotors" /id="U2566" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.437562437562438" /psig="0.994005994005994" /xcortree=2864 /SigmaFactorBS="tttcgtctcatctgccgctatttcacgccaaatcgtttTTGC ggcatccaacgcagcACTGGTACAATAAAAAGCAAatatatgaagggattgattcatt a" /listShort="S1259, yuzK, S1258, sufC, sufD, sufS, iscU, sufB, S1257" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3226794) /Source="Nicolas_upshifts" /id="U2566" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.437562437562438" /psig="0.994005994005994" /xcortree=2864 /SigmaFactorBS="tttcgtctcatctgccgctatttcacgccaaatcgtttTTGC ggcatccaacgcagcACTGGTACAATAAAAAGCAAatatatgaagggattgattcatt a" /listShort="S1259, yuzK, S1258, sufC, sufD, sufS, iscU, sufB, S1257" /GFF_Attribute="listLong" S_feature complement(3226796..3226902) /Source="Nicolas_S_feature" /locus_tag="new_3361198_3361304_c" /HighExp="S8, S5, S7, S6, S4, BT, ferm, nit, S3, G/S" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigGF" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S1260" promotor_-35 complement(3226813..3226816) /Source="Nicolas_upshift_promotors" /id="U2566" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.437562437562438" /psig="0.994005994005994" /xcortree=2864 /SigmaFactorBS="tttcgtctcatctgccgctatttcacgccaaatcgtttTTGC ggcatccaacgcagcACTGGTACAATAAAAAGCAAatatatgaagggattgattcatt a" /listShort="S1259, yuzK, S1258, sufC, sufD, sufS, iscU, sufB, S1257" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3226903..3227280) /gene="yurZ" /locus_tag="BSU_32720" /old_locus_tag="BSU32720" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_391151.1" /db_xref="EnsemblGenomes-Gn:BSU32720" /db_xref="EnsemblGenomes-Tr:CAB15261" /db_xref="GOA:O32166" /db_xref="InterPro:IPR003779" /db_xref="InterPro:IPR029032" /db_xref="SubtiList:BG14012" /db_xref="UniProtKB/Swiss-Prot:O32166" /translation="MEGFSLNQDRGSMQDALKQYKHGLGTFEQKMPLMGRKFNEFTEQ CFAGNSLTEREKQLIALGIAINAQDEYCMIYHTKGCLDQGASEENILEAVSVAAAFGG GAAFSQGVTVVQQCIEEFGNTTH*" gene complement(3226903..3227280) /gene="yurZ" /locus_tag="BSU_32720" /old_locus_tag="BSU32720" promotor_-10 complement(3227297..3227308) /Source="Nicolas_upshift_promotors" /id="U2567" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=935 /SigmaFactorBS="actgaaaccccggatgagaattccggggtttttttCGCGTAT tttcctaaaagctGTTCATAATAAAaaggaatgttaaacagatggagggattttcttt g" /listShort="yurZ, S1260, S1259, yuzK, S1258" /listLong="sufC, sufD, sufS, iscU, sufB, S1257" /label="promotor_-10" upshifts complement(3227303) /Source="Nicolas_upshifts" /id="U2567" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=935 /SigmaFactorBS="actgaaaccccggatgagaattccggggtttttttCGCGTAT tttcctaaaagctGTTCATAATAAAaaggaatgttaaacagatggagggattttcttt g" /listShort="yurZ, S1260, S1259, yuzK, S1258" /listLong="sufC, sufD, sufS, iscU, sufB, S1257" promotor_-35 complement(3227322..3227328) /Source="Nicolas_upshift_promotors" /id="U2567" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=935 /SigmaFactorBS="actgaaaccccggatgagaattccggggtttttttCGCGTAT tttcctaaaagctGTTCATAATAAAaaggaatgttaaacagatggagggattttcttt g" /listShort="yurZ, S1260, S1259, yuzK, S1258" /listLong="sufC, sufD, sufS, iscU, sufB, S1257" /label="promotor_-35" CDS complement(3227365..3228189) /gene="metQ" /locus_tag="BSU_32730" /old_locus_tag="BSU32730" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:10094622, 12910260, 14990259, 16109943, 17038623" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10094622, 12910260, 14990259, 16109943, 17038623; Product type t : transporter" /codon_start=1 /transl_table=11 /product="methionine ABC transporter, substrate binding lipoprotein" /protein_id="NP_391152.1" /db_xref="EnsemblGenomes-Gn:BSU32730" /db_xref="EnsemblGenomes-Tr:CAB15262" /db_xref="GOA:O32167" /db_xref="InterPro:IPR004872" /db_xref="PDB:4GOT" /db_xref="SubtiList:BG14013" /db_xref="UniProtKB/Swiss-Prot:O32167" /translation="MKKLFLGALLLVFAGVMAACGSNNGAESGKKEIVVAATKTPHAE ILKEAEPLLKEKGYTLKVKVLSDYKMYNKALADKEVDANYFQHIPYLEQEMKENTDYK LVNAGAVHLEPFGIYSKTYKSLKDLPDGATIILTNNVAEQGRMLAMLENAGLITLDSK VETVDATLKDIKKNPKNLEFKKVAPELTAKAYENKEGDAVFINVNYAIQNKLNPKKDA IEVESTKNNPYANIIAVRKGEEDSAKIKALMEVLHSKKIKDFIEKKYDGAVLPVSE*" gene complement(3227365..3228189) /gene="metQ" /locus_tag="BSU_32730" /old_locus_tag="BSU32730" downshifts complement(3227373) /Source="Nicolas_upshifts" /id="D1694" /incds=0 /nref=167 /ntot=246 /MaxReadThrough="2.13581" /MaxDrop="6.33517" /score="28.8468637" /energy="-12.6" /TU="NA" /idTUdmin="U2569" /TUdmin="-5" /isTUend="TRUE" downshifts complement(3227522) /Source="Nicolas_upshifts" /id="D1695" /incds=1 /nref=2 /ntot=171 /MaxReadThrough="6.93658" /MaxDrop="2.3341" /score="28.8468637" /energy="-12.6" /TU="U2569" /idTUdmin="U2569" /TUdmin="-154" /isTUend="FALSE" promotor_-35 3227549..3227554 /Source="Nicolas_upshift_promotors" /id="U2568" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.957042957042957" /psig="0.957042957042957" /xcortree=1218 /SigmaFactorBS="gtttttcgttgattctacttcaattgcgtcttttttaGGATT TaatttattttggatcGCATAGTTTACATTGATGAagaccgcgtctccttctttgttt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3227570..3227588 /Source="Nicolas_upshift_promotors" /id="U2568" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.957042957042957" /psig="0.957042957042957" /xcortree=1218 /SigmaFactorBS="gtttttcgttgattctacttcaattgcgtcttttttaGGATT TaatttattttggatcGCATAGTTTACATTGATGAagaccgcgtctccttctttgttt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3227572 /Source="Nicolas_upshifts" /id="U2568" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.957042957042957" /psig="0.957042957042957" /xcortree=1218 /SigmaFactorBS="gtttttcgttgattctacttcaattgcgtcttttttaGGATT TaatttattttggatcGCATAGTTTACATTGATGAagaccgcgtctccttctttgttt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" CDS complement(3228203..3228871) /gene="metP" /locus_tag="BSU_32740" /old_locus_tag="BSU32740" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:10094622, 12910260, 14990259, 15849754, 16850406, 17038623" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10094622, 12910260, 14990259, 15849754, 16850406, 17038623; Product type t : transporter" /codon_start=1 /transl_table=11 /product="methionine ABC transporter, permease component" /protein_id="NP_391153.1" /db_xref="EnsemblGenomes-Gn:BSU32740" /db_xref="EnsemblGenomes-Tr:CAB15263" /db_xref="GOA:O32168" /db_xref="InterPro:IPR000515" /db_xref="InterPro:IPR035906" /db_xref="SubtiList:BG14014" /db_xref="UniProtKB/Swiss-Prot:O32168" /translation="MFEKYFPNVDLTELWNATYETLYMTLISLLFAFVIGVILGLLLF LTSKGSLWQNKAVNSVIAAVVNIFRSIPFLILIILLLGFTKFLVGTILGPNAALPALV IGSAPFYARLVEIALREVDKGVIEAAKSMGAKTSTIIFKVLIPESMPALISGITVTAI ALIGSTAIAGAIGSGGLGNLAYVEGYQSNNADVTFVATVFILIIVFIIQIIGDLITNI IDKR*" gene complement(3228203..3228871) /gene="metP" /locus_tag="BSU_32740" /old_locus_tag="BSU32740" CDS complement(3228864..3229889) /gene="metN" /locus_tag="BSU_32750" /old_locus_tag="BSU32750" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:10094622, 12910260, 14990259, 17038623" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10094622, 12910260, 14990259, 17038623; Product type t: transporter" /codon_start=1 /transl_table=11 /product="methionine ABC transporter (ATP-binding protein)" /protein_id="NP_391154.1" /db_xref="EnsemblGenomes-Gn:BSU32750" /db_xref="EnsemblGenomes-Tr:CAB15264" /db_xref="GOA:O32169" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR017871" /db_xref="InterPro:IPR017908" /db_xref="InterPro:IPR018449" /db_xref="InterPro:IPR026253" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG14015" /db_xref="UniProtKB/Swiss-Prot:O32169" /translation="MINLQDVSKVYKSKHGDVNAVQNVSLSIKKGEIFGIIGYSGAGK SSLIRLLNGLEKPTSGTVEVAGTKINEVNGRGLRKARHEISMIFQHFNLLWSRTVRDN IMFPLEIAGVKKSERIKRANELIKLVGLEGKEKSYPSQLSGGQKQRVGIARALANNPK VLLCDEATSALDPQTTDSILDLLSDINERLGLTIVLITHEMHVIRKICNRVAVMENGK VVEEGEVLDVFKNPKEQMTKRFVQQVTEPEETKETLQHLLDDTASGKMVQLTFVGESA EQPLITEMIRNFNVSVNILQGKISQTKDGAYGSLFIHIDGDEEEVQNVIRFINDKQVK AEVITNV*" gene complement(3228864..3229889) /gene="metN" /locus_tag="BSU_32750" /old_locus_tag="BSU32750" S_feature complement(3229890..3229994) /Source="Nicolas_S_feature" /locus_tag="new_3364292_3364396_c" /HighExp="MG 5, MG t5, MG 10, BMM, MG-0.2, GM 25, MG-0.1, MG 15, M9-exp, MG 25" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="1, 0.996" /TUlongSig="SigA" /TUlongPSig="0.999" /label="S1261" misc_RNA complement(3229995..3230101) /gene="mswH" /locus_tag="BSU_misc_RNA_53" /product="S-adenosylmethionine riboswitch" /experiment="publication(s) with functional evidences, PMID:10094622, 12626738, 12910260, 17381305, 18039762" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10094622, 12626738, 12910260, 17381305, 18039762; Product type n: RNA" /function="16.3: Control" gene complement(3229995..3230101) /gene="mswH" /locus_tag="BSU_misc_RNA_53" downshifts 3230064 /Source="Nicolas_upshifts" /id="D1696" /incds=0 /nref=2 /ntot=37 /MaxReadThrough="1.54417" /MaxDrop="5.51028" /score="-1.70178746" /energy="-11.2" /TU="NA" /idTUdmin="U2568" /TUdmin=2420 /isTUend="FALSE" promotor_-10 complement(3230128..3230147) /Source="Nicolas_upshift_promotors" /id="U2569" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.955044955044955" /psig=1 /xcortree=2424 /SigmaFactorBS="tataatagtaaaagttgacatcatttatttTATTGACAttta atcattcgccgTGCTATTCTACATTAAGAATttccggacgaaaaagactatatatttc t" /listShort="NA, S1261, metQ, metP, metN" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3230140) /Source="Nicolas_upshifts" /id="U2569" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.955044955044955" /psig=1 /xcortree=2424 /SigmaFactorBS="tataatagtaaaagttgacatcatttatttTATTGACAttta atcattcgccgTGCTATTCTACATTAAGAATttccggacgaaaaagactatatatttc t" /listShort="NA, S1261, metQ, metP, metN" /GFF_Attribute="listLong" S_feature complement(3230142..3230215) /Source="Nicolas_S_feature" /locus_tag="new_3364544_3364617_c" /HighExp="M9-stat, S2, LoTm, T5.0H, HiOs, B60, S3, T3.30H, LPhT, T3.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="0.996, 0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S1262" promotor_-35 complement(3230163..3230170) /Source="Nicolas_upshift_promotors" /id="U2569" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.955044955044955" /psig=1 /xcortree=2424 /SigmaFactorBS="tataatagtaaaagttgacatcatttatttTATTGACAttta atcattcgccgTGCTATTCTACATTAAGAATttccggacgaaaaagactatatatttc t" /listShort="NA, S1261, metQ, metP, metN" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3230216..3230560) /gene="yusD" /locus_tag="BSU_32760" /old_locus_tag="BSU32760" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_391155.1" /db_xref="EnsemblGenomes-Gn:BSU32760" /db_xref="EnsemblGenomes-Tr:CAB15265" /db_xref="InterPro:IPR003033" /db_xref="InterPro:IPR036527" /db_xref="SubtiList:BG14016" /db_xref="UniProtKB/Swiss-Prot:O32170" /translation="MEKAEVLEDEYQHLFLKPLLNASTLLITFQGEAEALTVSINEQG EMKKVSPPQTSNLTFYGNQTEIIDLLHGDISLQHLIQSGSLKVKGSFRALLKLEAILW LTNGFFQRILKN*" gene complement(3230216..3230560) /gene="yusD" /locus_tag="BSU_32760" /old_locus_tag="BSU32760" S_feature complement(3230561..3230666) /Source="Nicolas_S_feature" /locus_tag="new_3364963_3365068_c" /HighExp="LPhT, HiOs, M9-stat, dia5, T2.0H, Diami, T1.30H, T0.30H, T2.30H, T4.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigGF, SigA, SigA" /TUshortPSig="1, 0.996, 0.999" /TUlongSig="SigA" /TUlongPSig=1 /label="S1263" CDS complement(3230667..3230987) /gene="yusE" /locus_tag="BSU_32770" /old_locus_tag="BSU32770" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15937154, 25875741; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative thiol-disulfide oxidoreductase with thioredoxin domain" /protein_id="NP_391156.1" /db_xref="EnsemblGenomes-Gn:BSU32770" /db_xref="EnsemblGenomes-Tr:CAB15266" /db_xref="GOA:O32171" /db_xref="InterPro:IPR005746" /db_xref="InterPro:IPR013766" /db_xref="InterPro:IPR036249" /db_xref="SubtiList:BG14017" /db_xref="UniProtKB/Swiss-Prot:O32171" /translation="MKELQEHELDHIEDDVYLLYLYTPFCGTCQLASKMLTVVKEMLP DVAFYQNNVNYSPTFAKAYQIESVPCFLLFKGGKMVERGYAFHSVSYLYELIKQKSSS ASHL*" gene complement(3230667..3230987) /gene="yusE" /locus_tag="BSU_32770" /old_locus_tag="BSU32770" CDS complement(3230989..3231429) /gene="yusF" /locus_tag="BSU_32780" /old_locus_tag="BSU32780" /function="16.3: Control" /function="16.11: Scavenge (Catabolism)" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 12794188; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative ribonuclease" /protein_id="NP_391157.1" /db_xref="EnsemblGenomes-Gn:BSU32780" /db_xref="EnsemblGenomes-Tr:CAB15267" /db_xref="GOA:O32172" /db_xref="InterPro:IPR006171" /db_xref="InterPro:IPR034141" /db_xref="SubtiList:BG14018" /db_xref="UniProtKB/Swiss-Prot:O32172" /translation="MLAVNFTAFFYNLNISNLTRQVNKMKMDELEKVMIVEGKSDKEK IESVLNEPMRIICTNGTISQLRLEELADELYDKDVYILVDADESGEKLRKQLKREFNE ACHLHVDRAYKEVAAAPRHHIASVLLRANLNVHTIFLERKSRGV*" gene complement(3230989..3231429) /gene="yusF" /locus_tag="BSU_32780" /old_locus_tag="BSU32780" CDS complement(3231429..3231665) /gene="yusG" /locus_tag="BSU_32790" /old_locus_tag="BSU32790" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_391158.1" /db_xref="EnsemblGenomes-Gn:BSU32790" /db_xref="EnsemblGenomes-Tr:CAB15268" /db_xref="InterPro:IPR020140" /db_xref="SubtiList:BG14019" /db_xref="UniProtKB/Swiss-Prot:O32173" /translation="MAFDKQKLDVTNDVTGRFQNGRLSLYHDNEMIGQMTSMNEYELK SGYSFENEKFYKTADVVSGDDAKYVDCDYENGWC*" gene complement(3231429..3231665) /gene="yusG" /locus_tag="BSU_32790" /old_locus_tag="BSU32790" downshifts complement(3231441) /Source="Nicolas_upshifts" /id="D1697" /incds=0 /nref=35 /ntot=245 /MaxReadThrough="6.00162" /MaxDrop="3.9147" /score="-1.53913693" /energy="-11" /TU="U2570,U2571,U2572" /idTUdmin="U2574" /TUdmin=723 /isTUend="FALSE" upshifts complement(3231680) /Source="Nicolas_upshifts" /id="U2570" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=805 /SigmaFactorBS="agatgacacaagaagactaaaacAGGATAGccgtaaaagcaa ttGGACACGCTAACgttatgggaggtgtccaatatggctttcgacaaacaaaagctcg a" /listShort="yusG, yusF, yusE, S1263, yusD" /GFF_Attribute="listLong" promotor_-10 complement(3231685..3231696) /Source="Nicolas_upshift_promotors" /id="U2570" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=805 /SigmaFactorBS="agatgacacaagaagactaaaacAGGATAGccgtaaaagcaa ttGGACACGCTAACgttatgggaggtgtccaatatggctttcgacaaacaaaagctcg a" /listShort="yusG, yusF, yusE, S1263, yusD" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 complement(3231711..3231717) /Source="Nicolas_upshift_promotors" /id="U2570" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=805 /SigmaFactorBS="agatgacacaagaagactaaaacAGGATAGccgtaaaagcaa ttGGACACGCTAACgttatgggaggtgtccaatatggctttcgacaaacaaaagctcg a" /listShort="yusG, yusF, yusE, S1263, yusD" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3231721..3232104) /gene="gcvH" /locus_tag="BSU_32800" /old_locus_tag="BSU32800" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2b: Function from indirect experimental evidences (e.g. phenotypes); PubMedId: 20882995, 21338421; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="glycine cleavage system protein H (lipoyl acceptor protein)" /protein_id="NP_391159.1" /db_xref="EnsemblGenomes-Gn:BSU32800" /db_xref="EnsemblGenomes-Tr:CAB15269" /db_xref="GOA:O32174" /db_xref="InterPro:IPR000089" /db_xref="InterPro:IPR002930" /db_xref="InterPro:IPR003016" /db_xref="InterPro:IPR011053" /db_xref="InterPro:IPR017453" /db_xref="InterPro:IPR033753" /db_xref="SubtiList:BG14020" /db_xref="UniProtKB/Swiss-Prot:O32174" /translation="MSIPKDLRYSGEHEWVKVEGEKARIGITHFAQSELGDIVFVELP EVGAEIKADEPFGSVESVKTVSELYAPINGTVVEVNEDLDDSPEFVNESPYEKAWMIV VEPSDASEIEKLMTAEQYEEMTQED*" gene complement(3231721..3232104) /gene="gcvH" /locus_tag="BSU_32800" /old_locus_tag="BSU32800" promotor_-10 complement(3232131..3232150) /Source="Nicolas_upshift_promotors" /id="U2571" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.601398601398601" /psig="0.996003996003996" /xcortree=2237 /SigmaFactorBS="aagaagaccaatttgaagaaaactgggcttaaTGTAAATTtt ttttgaaaagTGTGGTATCTTCTTATTGTAgtgctgtaaaaaatggagggattcaatt g" /listShort="yusH, yusG, yusF, yusE, S1263, yusD, S1262, NA, S1261, metQ" /listLong="metP, metN" /label="promotor_-10" upshifts complement(3232142) /Source="Nicolas_upshifts" /id="U2571" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.601398601398601" /psig="0.996003996003996" /xcortree=2237 /SigmaFactorBS="aagaagaccaatttgaagaaaactgggcttaaTGTAAATTtt ttttgaaaagTGTGGTATCTTCTTATTGTAgtgctgtaaaaaatggagggattcaatt g" /listShort="yusH, yusG, yusF, yusE, S1263, yusD, S1262, NA, S1261, metQ" /listLong="metP, metN" promotor_-35 complement(3232163..3232170) /Source="Nicolas_upshift_promotors" /id="U2571" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.601398601398601" /psig="0.996003996003996" /xcortree=2237 /SigmaFactorBS="aagaagaccaatttgaagaaaactgggcttaaTGTAAATTtt ttttgaaaagTGTGGTATCTTCTTATTGTAgtgctgtaaaaaatggagggattcaatt g" /listShort="yusH, yusG, yusF, yusE, S1263, yusD, S1262, NA, S1261, metQ" /listLong="metP, metN" /label="promotor_-35" CDS complement(3232171..3232527) /gene="yusI" /locus_tag="BSU_32810" /old_locus_tag="BSU32810" /EC_number="1.20.4.-" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative oxidoreductase with thioredoxin domain and regulator domain" /protein_id="NP_391160.1" /db_xref="EnsemblGenomes-Gn:BSU32810" /db_xref="EnsemblGenomes-Tr:CAB15270" /db_xref="GOA:O32175" /db_xref="InterPro:IPR006504" /db_xref="InterPro:IPR006660" /db_xref="InterPro:IPR036249" /db_xref="SubtiList:BG14021" /db_xref="UniProtKB/Swiss-Prot:O32175" /translation="MSLTFYWYPKCGTCRKAKKWLEEHGKEINEIHIAEQPPSKEELK ALYEKSGLDLKKFFNTSGMKYRELNLKEKLYHMSEDEQLELLASDGMLIKRPLTTDGE KVTVGFKEDQFEENWA*" gene complement(3232171..3232527) /gene="yusI" /locus_tag="BSU_32810" /old_locus_tag="BSU32810" promotor_-10 complement(3232550..3232569) /Source="Nicolas_upshift_promotors" /id="U2572" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.562437562437562" /psig="0.999000999001" /xcortree=2011 /SigmaFactorBS="atgcgcggagctcttttttaagaagcactgttTTAGGTtttt aaaacaaacTGTGTTAAAATAACCTCGATtattttattgagggggaagaagatgtcgt t" /listShort="yusI, yusH, yusG, yusF, yusE, S1263, yusD, S1262" /listLong="NA, S1261, metQ, metP, metN" /label="promotor_-10" upshifts complement(3232560) /Source="Nicolas_upshifts" /id="U2572" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.562437562437562" /psig="0.999000999001" /xcortree=2011 /SigmaFactorBS="atgcgcggagctcttttttaagaagcactgttTTAGGTtttt aaaacaaacTGTGTTAAAATAACCTCGATtattttattgagggggaagaagatgtcgt t" /listShort="yusI, yusH, yusG, yusF, yusE, S1263, yusD, S1262" /listLong="NA, S1261, metQ, metP, metN" promotor_-35 complement(3232583..3232588) /Source="Nicolas_upshift_promotors" /id="U2572" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.562437562437562" /psig="0.999000999001" /xcortree=2011 /SigmaFactorBS="atgcgcggagctcttttttaagaagcactgttTTAGGTtttt aaaacaaacTGTGTTAAAATAACCTCGATtattttattgagggggaagaagatgtcgt t" /listShort="yusI, yusH, yusG, yusF, yusE, S1263, yusD, S1262" /listLong="NA, S1261, metQ, metP, metN" /label="promotor_-35" CDS complement(3232638..3234422) /gene="fadE" /locus_tag="BSU_32820" /old_locus_tag="BSU32820" /EC_number="1.3.99.-" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:17189250, 21398533" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 17189250, 21398533; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="acyl-CoA dehydrogenase (FAD dependent)" /protein_id="NP_391161.1" /db_xref="EnsemblGenomes-Gn:BSU32820" /db_xref="EnsemblGenomes-Tr:CAB15271" /db_xref="GOA:O32176" /db_xref="InterPro:IPR006089" /db_xref="InterPro:IPR006091" /db_xref="InterPro:IPR009075" /db_xref="InterPro:IPR009100" /db_xref="InterPro:IPR013786" /db_xref="InterPro:IPR036250" /db_xref="InterPro:IPR037069" /db_xref="SubtiList:BG14022" /db_xref="UniProtKB/Swiss-Prot:O32176" /translation="MAKKAADVQKGGGFLIEDVTYDQMYTPEDFTDEHKMIAKTTEDY IEQDVLPHIDDIENHQFEHSVRLLKKAGELGLLGADVPEEYGGLGLDKISSALITEKF SRAGSFSLSYGAHVGIGSLPIVFFGSEEQKKKYLPGLASGEKIAAYALTEPGSGSDAL GAKTTAVLNEAGTHYVLTGEKQWITNSAFADVFVVYAKVDGDKFSAFIVEKEFPGVST GPEEKKMGIKGSSTRTLILDQAEVPKENLLGEIGKGHVIAFNILNIGRYKLAVGTIGA SKRVIELSAAYANQRRQFKTPIAGFSLTQEKIGTMASRLYAMESSVYRTVGLFEDNMS QFTAEDLKDGRQIAKSIAEYAIECSLNKVFGSETLDYIVDEGVQIHGGYGFMQEYEVE RAYRDSRINRIFEGTNEINRLIVPSTFLKKALKGELPLFEKAQSLQEELMMLMPEEPG SGVLEQEKYIVKQAKKIALFAAGLAAQKYGKAIDREQEILVNVADIVSNVYAMESAVL RTEKAIAAQGAEKAAQKVLYTEIFVQEAFNEIEAHAKESLIAMEEGDSLRMMLSALRK LTRVTPKNVIQKKREAAAGIFEAEKYTV*" gene complement(3232638..3234422) /gene="fadE" /locus_tag="BSU_32820" /old_locus_tag="BSU32820" downshifts complement(3232648) /Source="Nicolas_upshifts" /id="D1698" /incds=0 /nref=24 /ntot=46 /MaxReadThrough="4.78872" /MaxDrop="6.88218" /score="31.8022607" /energy="-16.4" /TU="U2574" /idTUdmin="U2576" /TUdmin=0 /isTUend="TRUE" CDS complement(3234437..3235612) /gene="fadA" /locus_tag="BSU_32830" /old_locus_tag="BSU32830" /EC_number="2.3.1.16" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:17189250, 21398533" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 17189250, 21398533; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="acetyl-CoA C-acyltransferase" /protein_id="NP_391162.1" /db_xref="EnsemblGenomes-Gn:BSU32830" /db_xref="EnsemblGenomes-Tr:CAB15272" /db_xref="GOA:O32177" /db_xref="InterPro:IPR002155" /db_xref="InterPro:IPR016039" /db_xref="InterPro:IPR020610" /db_xref="InterPro:IPR020613" /db_xref="InterPro:IPR020615" /db_xref="InterPro:IPR020616" /db_xref="InterPro:IPR020617" /db_xref="SubtiList:BG14023" /db_xref="UniProtKB/Swiss-Prot:O32177" /translation="MKEAVIVSGARTPVGKAKKGSLATVRPDDLGAICVKETLKRAGG YEGNIDDLIIGCATPEAEQGLNMARNIGALAGLPYTVPAITVNRYCSSGLQSIAYAAE KIMLGAYDTAIAGGAESMSQVPMMGHVTRPNLALAEKAPEYYMSMGHTAEQVAKKYGV SREDQDAFAVRSHQNAAKALAEGKFKDEIVPVEVTVTEIGEDHKPMEKQFVFSQDEGV RPQTTADILSTLRPAFSVDGTVTAGNSSQTSDGAAAVMLMDREKADALGLAPLVKFRS FAVGGVPPEVMGIGPVEAIPRALKLAGLQLQDIGLFELNEAFASQAIQVIRELGIDEE KVNVNGGAIALGHPLGCTGTKLTLSLIHEMKRRNEQFGVVTMCIGGGMGAAGVFELC* " gene complement(3234437..3235612) /gene="fadA" /locus_tag="BSU_32830" /old_locus_tag="BSU32830" CDS complement(3235623..3237992) /gene="fadN" /locus_tag="BSU_32840" /old_locus_tag="BSU32840" /EC_number="1.1.1.35" /EC_number="4.2.1.17" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2b: Function from indirect experimental evidences (e.g. phenotypes); PubMedId: 17189250, 22720735; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="bifunctional enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase" /protein_id="NP_391163.2" /db_xref="EnsemblGenomes-Gn:BSU32840" /db_xref="EnsemblGenomes-Tr:CAB15273" /db_xref="GOA:O32178" /db_xref="InterPro:IPR001753" /db_xref="InterPro:IPR006108" /db_xref="InterPro:IPR006176" /db_xref="InterPro:IPR008927" /db_xref="InterPro:IPR013328" /db_xref="InterPro:IPR029045" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG14024" /db_xref="UniProtKB/Swiss-Prot:O32178" /translation="MHKHIRKAAVLGSGVMGSGIAAHLANIGIPVLLLDIVPNDLTKE EEKKGLTKDSSEVRSRLSRQAMKKLLKQKPAPLTSAKNTSYITPGNLEDDAEKLKEAD WIIEVVVENLEVKKKIFALVDEHRKTGSIVSSNTSGISVQEMAEGRSDDFKAHFLGTH FFNPARYLKLLEIIPIKETDPDILKFMTAFGENVLGKGVVTAKDTPNFIANRIGTYGL LVTVQEMLKGGYQVGEVDSITGPLIGRPKSATFRTLDVVGLDTFAHVARNVYDKADGD EKEVFRIPSFMNDMLEKGWIGSKAGQGFYKKEGKTIYELDPVTLTYGERTKMKSPALE AAKQAKGTKAKMKALIYSDDRAGRLLWNITSQTLLYSAELLGEIADDIHAIDQAMKWG FGWELGPFEMWDAIGLKQSAEKLEQLGADMPGWIKEMLDKGNETFYIKENGTVFYYDR GEYRAVKENKKRIHLQALKETKGVIAKNSGASLIDLGDDVALLEFHSKSNAIGLDIIQ MIHKGLEETERNYKGLVIGNQGKNFCVGANLAMILMEVQDDNFLEVDFVIRRFQETMM KIKYSAKPVVAAPFGMTLGGGTEACLPAARIQAASEAYMGLVESGVGLIPGGGGNKEL YINHLRRGHDPMNAAMKTFETIAMAKVSASAQEAREMNILKETDQISVNQDHLLYDAK QLAASLYDTGWRPPVKEKVKVPGETGYAALLLGAEQMKLSGYISEHDFKIAKKLAYVI AGGKVPFGTEVDEEYLLEIEREAFLSLSGEAKSQARMQHMLVKGKPLRN*" gene complement(3235623..3237992) /gene="fadN" /locus_tag="BSU_32840" /old_locus_tag="BSU32840" promotor_-35 3237411..3237416 /Source="Nicolas_upshift_promotors" /id="U2573" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1035 /SigmaFactorBS="tcggtgtgtcctttgctgtaacaacgcctttcccgagGACAT TttctccgaaagctgTCATAAACTTTAAAATATCaggatccgtttccttaatcggaat g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3237431..3237449 /Source="Nicolas_upshift_promotors" /id="U2573" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1035 /SigmaFactorBS="tcggtgtgtcctttgctgtaacaacgcctttcccgagGACAT TttctccgaaagctgTCATAAACTTTAAAATATCaggatccgtttccttaatcggaat g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3237434 /Source="Nicolas_upshifts" /id="U2573" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1035 /SigmaFactorBS="tcggtgtgtcctttgctgtaacaacgcctttcccgagGACAT TttctccgaaagctgTCATAAACTTTAAAATATCaggatccgtttccttaatcggaat g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 complement(3238060..3238079) /Source="Nicolas_upshift_promotors" /id="U2574" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.622377622377622" /psig=1 /xcortree=375 /SigmaFactorBS="catacaaaaaaataacaaattagCTATTGAAgtcgaaccgga aaTCTTTTAAGATGAAAGAAGAaacgggtttcattttttttagtcaaaaaatgaatga c" /listShort="fadN, fadA, fadE, yusI" /listLong="yusH, yusG, yusF, yusE, S1263, yusD" /label="promotor_-10" upshifts complement(3238063) /Source="Nicolas_upshifts" /id="U2574" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.622377622377622" /psig=1 /xcortree=375 /SigmaFactorBS="catacaaaaaaataacaaattagCTATTGAAgtcgaaccgga aaTCTTTTAAGATGAAAGAAGAaacgggtttcattttttttagtcaaaaaatgaatga c" /listShort="fadN, fadA, fadE, yusI" /listLong="yusH, yusG, yusF, yusE, S1263, yusD" S_feature complement(3238071..3238337) /Source="Nicolas_S_feature" /locus_tag="new_3372473_3372739_c" /HighExp="S8, S6, S7, BT, B36, G/S, B60, S5, Pyr, S3" /AntisenseName="yuzL" /AntisenseCor="0.77564732124057401" /AntisenseRegPval="-54.6" /CDS_PredictionProba="NA" /TUshortSig="SigK" /TUshortPSig="0.995" /TUlongSig="NA" /TUlongPSig="NA" /label="S1264" promotor_-35 complement(3238093..3238100) /Source="Nicolas_upshift_promotors" /id="U2574" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.622377622377622" /psig=1 /xcortree=375 /SigmaFactorBS="catacaaaaaaataacaaattagCTATTGAAgtcgaaccgga aaTCTTTTAAGATGAAAGAAGAaacgggtttcattttttttagtcaaaaaatgaatga c" /listShort="fadN, fadA, fadE, yusI" /listLong="yusH, yusG, yusF, yusE, S1263, yusD" /label="promotor_-35" promotor_-35 3238118..3238124 /Source="Nicolas_upshift_promotors" /id="U2575" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=890 /SigmaFactorBS="ctaatttgttattttttTGTATGAagcctataaaagtcGGGC AACTTAAGcccggaggtgaagggaatggtacgagagaaaaaaaatccgtcttcagcgg c" /listShort="yuzL, S1265, yuzM, yusN" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3238139..3238150 /Source="Nicolas_upshift_promotors" /id="U2575" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=890 /SigmaFactorBS="ctaatttgttattttttTGTATGAagcctataaaagtcGGGC AACTTAAGcccggaggtgaagggaatggtacgagagaaaaaaaatccgtcttcagcgg c" /listShort="yuzL, S1265, yuzM, yusN" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3238161 /Source="Nicolas_upshifts" /id="U2575" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=890 /SigmaFactorBS="ctaatttgttattttttTGTATGAagcctataaaagtcGGGC AACTTAAGcccggaggtgaagggaatggtacgagagaaaaaaaatccgtcttcagcgg c" /listShort="yuzL, S1265, yuzM, yusN" /GFF_Attribute="listLong" CDS 3238167..3238313 /gene="yuzL" /locus_tag="BSU_32849" /old_locus_tag="BSU32849" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 17189250" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="YP_003097783.1" /db_xref="EnsemblGenomes-Gn:BSU32849" /db_xref="EnsemblGenomes-Tr:CAX52689" /db_xref="InterPro:IPR025625" /db_xref="UniProtKB/Swiss-Prot:C0H3R0" /translation="MVREKKNPSSAAVSAASVKGDAGPTQHYGGGKRTSQNQQYKKHN MGQS*" gene 3238167..3238313 /gene="yuzL" /locus_tag="BSU_32849" /old_locus_tag="BSU32849" S_feature 3238314..3239340 /Source="Nicolas_S_feature" /locus_tag="new_3372716_3373742" /HighExp="S8, S5, S7, S4, S6, nit, ferm, T5.0H, S3, LoTm" /AntisenseName="fadM" /AntisenseCor="0.80952501049450498" /AntisenseRegPval="-63" /CDS_PredictionProba="NA" /TUshortSig="SigGF" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S1265" CDS complement(3238338..3239246) /gene="putM" /locus_tag="BSU_32850" /old_locus_tag="BSU32850" /EC_number="1.5.5.2" /function="3.2: Degradation" /experiment="publication(s) with functional evidences, PMID:17189250, 17536821, 21398533" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 17189250, 17536821, 21398533; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="proline dehydrogenase 1" /protein_id="NP_391164.1" /db_xref="EnsemblGenomes-Gn:BSU32850" /db_xref="EnsemblGenomes-Tr:CAB15274" /db_xref="GOA:O32179" /db_xref="InterPro:IPR002872" /db_xref="InterPro:IPR008219" /db_xref="InterPro:IPR015659" /db_xref="InterPro:IPR029041" /db_xref="SubtiList:BG14025" /db_xref="UniProtKB/Swiss-Prot:O32179" /translation="MLRHVFLFLSQNKTLTKFAKAYGTRLGARRFVAGDTIESAVKTV KRLNRSGLCATIDYLGEYAASEKEANQVAEECKKAIQAIAEHQLNSELSLKLTSIGLD LSEELALTHLRAILSVAKQYDVAVTIDMEDYSHYEQTLSIYRQCKQEFEKLGTVIQAY LYRAAEDIRKMRDLKPNLRLVKGAYKESAAVAFPDKRGTDLHFQSLIKLQLLSGNYTA VATHDDDIIAFTKQLVAEHQIPASQFEFQMLYGIRPERQKELAKEGYRMRVYVPYGTD WFSYFMRRIAERPANAAFVLKGILKK*" gene complement(3238338..3239246) /gene="putM" /locus_tag="BSU_32850" /old_locus_tag="BSU32850" S_feature complement(3239247..3239769) /Source="Nicolas_S_feature" /locus_tag="new_3373649_3374171_c" /HighExp="S8, S6, S7, BT, B36, B60, G/S, Pyr, S5, SMMPr" /AntisenseName="yuzM" /AntisenseCor="0.77827902986544495" /AntisenseRegPval="-55.2" /CDS_PredictionProba="NA" /TUshortSig="SigK" /TUshortPSig="0.995" /TUlongSig="NA" /TUlongPSig="NA" /label="S1266" CDS 3239341..3239586 /gene="yuzM" /locus_tag="BSU_32859" /old_locus_tag="BSU32859" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="YP_003097784.1" /db_xref="EnsemblGenomes-Gn:BSU32859" /db_xref="EnsemblGenomes-Tr:CAX52690" /db_xref="InterPro:IPR012347" /db_xref="UniProtKB/Swiss-Prot:C0H3R1" /translation="MDNQQQSQMPPSVISTKDHLYLNDMLNWNLLAMKKAHFMAQQCQ DQTLKQELDRVGHMHHDHYQRILKHLQPGQQQSGYIQ*" gene 3239341..3239586 /gene="yuzM" /locus_tag="BSU_32859" /old_locus_tag="BSU32859" CDS 3239599..3239931 /gene="yusN" /locus_tag="BSU_32860" /old_locus_tag="BSU32860" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="putative spore coat-like protein" /protein_id="NP_391165.1" /db_xref="EnsemblGenomes-Gn:BSU32860" /db_xref="EnsemblGenomes-Tr:CAB15275" /db_xref="InterPro:IPR012347" /db_xref="InterPro:IPR012851" /db_xref="SubtiList:BG14026" /db_xref="UniProtKB/Swiss-Prot:O32180" /translation="MNQQNQKISNPQTPVPTTSEMNDRDFVNELLTTEKYMTTAYCTA LHEFSHESLYQDIQSIFDESQKAQRKLYDLMFQYGWYSVEAEDSQKLQQSYQKFQQTI QQQSPYQQ*" gene 3239599..3239931 /gene="yusN" /locus_tag="BSU_32860" /old_locus_tag="BSU32860" promotor_-10 complement(3239752..3239771) /Source="Nicolas_upshift_promotors" /id="U2576" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.995004995004995" /psig="0.995004995004995" /xcortree=1348 /SigmaFactorBS="ttggaacatgagatcatatagttttctttgcgcttTTTGTGA CTCatcaaaaatggatTGAATATCCTGATAAAGAGActcgtggctgaattcgtgcaag g" /listShort="S1266, fadM, S1264, fadN, fadA, fadE" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3239769) /Source="Nicolas_upshifts" /id="U2576" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.995004995004995" /psig="0.995004995004995" /xcortree=1348 /SigmaFactorBS="ttggaacatgagatcatatagttttctttgcgcttTTTGTGA CTCatcaaaaatggatTGAATATCCTGATAAAGAGActcgtggctgaattcgtgcaag g" /listShort="S1266, fadM, S1264, fadN, fadA, fadE" /GFF_Attribute="listLong" promotor_-35 complement(3239785..3239794) /Source="Nicolas_upshift_promotors" /id="U2576" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.995004995004995" /psig="0.995004995004995" /xcortree=1348 /SigmaFactorBS="ttggaacatgagatcatatagttttctttgcgcttTTTGTGA CTCatcaaaaatggatTGAATATCCTGATAAAGAGActcgtggctgaattcgtgcaag g" /listShort="S1266, fadM, S1264, fadN, fadA, fadE" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 3239920 /Source="Nicolas_upshifts" /id="D1699" /incds=0 /nref=24 /ntot=46 /MaxReadThrough="2.684" /MaxDrop="5.38418" /score="9.88876972" /energy="-10.2" /TU="NA" /idTUdmin="U2575" /TUdmin=0 /isTUend="TRUE" promotor_-35 3239992..3239999 /Source="Nicolas_upshift_promotors" /id="U2577" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.648351648351648" /psig="0.999000999001" /xcortree=2125 /SigmaFactorBS="gggcatctatcctttttttgtgtaaaatCAGTTGACttttca tttacgcTTATTTATATTTAATAAGCAttaactattttgtcattaaaatatatataca g" /listShort="yusO, yusP" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3240013..3240032 /Source="Nicolas_upshift_promotors" /id="U2577" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.648351648351648" /psig="0.999000999001" /xcortree=2125 /SigmaFactorBS="gggcatctatcctttttttgtgtaaaatCAGTTGACttttca tttacgcTTATTTATATTTAATAAGCAttaactattttgtcattaaaatatatataca g" /listShort="yusO, yusP" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3240024 /Source="Nicolas_upshifts" /id="U2577" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.648351648351648" /psig="0.999000999001" /xcortree=2125 /SigmaFactorBS="gggcatctatcctttttttgtgtaaaatCAGTTGACttttca tttacgcTTATTTATATTTAATAAGCAttaactattttgtcattaaaatatatataca g" /listShort="yusO, yusP" /GFF_Attribute="listLong" CDS 3240090..3240557 /gene="mdtR" /locus_tag="BSU_32870" /old_locus_tag="BSU32870" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:12923086, 19286808" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12923086, 19286808; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator (MarR family, low level antibiotic resistance)" /protein_id="NP_391166.1" /db_xref="EnsemblGenomes-Gn:BSU32870" /db_xref="EnsemblGenomes-Tr:CAB15276" /db_xref="GOA:O32181" /db_xref="InterPro:IPR000835" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="PDB:1S3J" /db_xref="SubtiList:BG14027" /db_xref="UniProtKB/Swiss-Prot:O32181" /translation="MKSADQLMSDIQLSLQALFQKIQPEMLESMEKQGVTPAQLFVLA SLKKHGSLKVSEIAERMEVKPSAVTLMADRLEQKNLIARTHNTKDRRVIDLSLTDEGD IKFEEVLAGRKAIMARYLSFLTEEEMLQAAHITAKLAQAAETDEKQNMKRGNG*" gene 3240090..3240557 /gene="mdtR" /locus_tag="BSU_32870" /old_locus_tag="BSU32870" CDS 3240554..3242179 /gene="mdtP" /locus_tag="BSU_32880" /old_locus_tag="BSU32880" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:15849754, 16850406, 19286808" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15849754, 16850406, 19286808; Product type t: transporter" /codon_start=1 /transl_table=11 /product="multidrug-efflux transporter" /protein_id="NP_391167.1" /db_xref="EnsemblGenomes-Gn:BSU32880" /db_xref="EnsemblGenomes-Tr:CAB15277" /db_xref="GOA:O32182" /db_xref="InterPro:IPR004638" /db_xref="InterPro:IPR005829" /db_xref="InterPro:IPR011701" /db_xref="InterPro:IPR020846" /db_xref="InterPro:IPR036259" /db_xref="SubtiList:BG14028" /db_xref="UniProtKB/Swiss-Prot:O32182" /translation="MKMSKEGKQSKRTLLITGLIIAMFFSALDGTIVGTAMPKIVGDL GGLSMMTWLTTAYLLTSTTIVPIAGKLADLLGRRIVYVSGLIIFMAASALCGMANNMT ELIIFRGLQGIGGGIMMPMAMIVIGDLFTGKQRAKFQGVFGAIYGLASVIGPQIGGWI VDSLNWKWVFYINLPVGIIAVIFIARGLQGRQQTGPINFDIAGIFTMIVGVVSLLLAL SFGGKDYAWDSWQILGLFALALIGIVSFIIVESKAKEPILPMYLFKNRTFTFLNLIGF FMSIGMFGAITFVPFFMQGIVGVSASESGTIMTPMMISMIITSIIGGQLVYKIGIKPQ IITGMLVMAGGFLLLTTLDLDTSKLVATSFMAIIGLGMGLVMPILTLALQESFSKEEL GVVTSSSQFFRSIGGTFGITMLGAVMNARSGNLLTDKLVPYLDSLPAQASSFAAQLKG MIDTNPQGLLQSLFSPDAVKQIPAAFSSHIVPILKTSLMDSLHSVFYTGLIFIAVGAV FTLFLKPIKLSNKKAEDQQEKEKAAKAVESPSH*" gene 3240554..3242179 /gene="mdtP" /locus_tag="BSU_32880" /old_locus_tag="BSU32880" downshifts 3242164 /Source="Nicolas_upshifts" /id="D1700" /incds=0 /nref=217 /ntot=257 /MaxReadThrough="0.3188" /MaxDrop="5.64223" /score="42.0555168" /energy="-17.7" /TU="NA" /idTUdmin="U2577" /TUdmin=0 /isTUend="TRUE" CDS complement(3242215..3242598) /gene="yusQ" /locus_tag="BSU_32890" /old_locus_tag="BSU32890" /EC_number="5.3.2.-" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2b: Function from indirect experimental evidences (e.g. phenotypes); PubMedId: 25219626; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="hydratase of unidentified specificity (tautomerase superfamily)" /protein_id="NP_391168.1" /db_xref="EnsemblGenomes-Gn:BSU32890" /db_xref="EnsemblGenomes-Tr:CAB15278" /db_xref="GOA:O32183" /db_xref="InterPro:IPR004370" /db_xref="InterPro:IPR014347" /db_xref="SubtiList:BG14029" /db_xref="UniProtKB/Swiss-Prot:O32183" /translation="MPFVQIHLRSGRSEVWLQKLSRTIHQSMIEEINVPEDDYFQVIR QYEKSEFFYDPFYLQVERTDELIYIHFTLKQSRTTEQKKALYRSIASRIHSELGVRKE DVFIMLAGNQDEDWSFGNGRAQMIE*" gene complement(3242215..3242598) /gene="yusQ" /locus_tag="BSU_32890" /old_locus_tag="BSU32890" CDS complement(3242617..3243006) /gene="yusR" /locus_tag="BSU_32900" /old_locus_tag="BSU32900" /EC_number="1.1.1.-" /function="16.11: Scavenge (Catabolism)" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15294834; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative 3-oxoacyl-acyl-carrier protein reductase" /protein_id="NP_391169.1" /db_xref="EnsemblGenomes-Gn:BSU32900" /db_xref="EnsemblGenomes-Tr:CAB15279" /db_xref="GOA:O32184" /db_xref="InterPro:IPR002347" /db_xref="InterPro:IPR020904" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG14030" /db_xref="UniProtKB/Swiss-Prot:O32184" /translation="MKGMFFCARAVVPFMKKSKDGAIVNVGSIAGITGAGSSMPYAVS KSAVHGLTKSLAHALAPEIRVSGVAPGAVATRWWAGREEKMKSMIGSLLLQCIAEPDD VAKLICSLIEQESLTGQIITIDSGQTL*" gene complement(3242617..3243006) /gene="yusR" /locus_tag="BSU_32900" /old_locus_tag="BSU32900" CDS complement(3243028..3243357) /gene="yusS" /locus_tag="BSU_32910" /old_locus_tag="BSU32910" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="conserved enzyme of unknown function" /protein_id="NP_391170.1" /db_xref="EnsemblGenomes-Gn:BSU32910" /db_xref="EnsemblGenomes-Tr:CAB15280" /db_xref="InterPro:IPR002347" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG14031" /db_xref="UniProtKB/Swiss-Prot:O32185" /translation="MNVLNKIALVTGGGTGIGKAASMELAKRGAIVAVNYSRSQSEAE ETVEMIQKAGGQAFAIQADVSKNSDVQDMIQAIVNTHGTVDILVNNASITRHIPMDDL EAATEDV*" gene complement(3243028..3243357) /gene="yusS" /locus_tag="BSU_32910" /old_locus_tag="BSU32910" promotor_-10 complement(3243392..3243411) /Source="Nicolas_upshift_promotors" /id="U2578" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.972027972027972" /psig=1 /xcortree=1537 /SigmaFactorBS="atcaatctgagtgatatctagtatctttaacaatCATTATAC gtaacatcaaagcTGGATTACAATGGAATCAGAaatatactttagtcaacagcaagga g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 3243399..3243406 /Source="Nicolas_upshift_promotors" /id="U2579" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.707292707292707" /psig="0.998001998001998" /xcortree=1789 /SigmaFactorBS="tgctgttgactaaagtatatttctgattCCATTGTAatccag ctttgatgTTACGTATAATGATTGTTAAagatactagatatcactcagattgatagta a" /listShort="yusT" /GFF_Attribute="listLong" /label="promotor_-35" upshifts complement(3243406) /Source="Nicolas_upshifts" /id="U2578" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.972027972027972" /psig=1 /xcortree=1537 /SigmaFactorBS="atcaatctgagtgatatctagtatctttaacaatCATTATAC gtaacatcaaagcTGGATTACAATGGAATCAGAaatatactttagtcaacagcaagga g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 3243421..3243440 /Source="Nicolas_upshift_promotors" /id="U2579" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.707292707292707" /psig="0.998001998001998" /xcortree=1789 /SigmaFactorBS="tgctgttgactaaagtatatttctgattCCATTGTAatccag ctttgatgTTACGTATAATGATTGTTAAagatactagatatcactcagattgatagta a" /listShort="yusT" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 complement(3243425..3243432) /Source="Nicolas_upshift_promotors" /id="U2578" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.972027972027972" /psig=1 /xcortree=1537 /SigmaFactorBS="atcaatctgagtgatatctagtatctttaacaatCATTATAC gtaacatcaaagcTGGATTACAATGGAATCAGAaatatactttagtcaacagcaagga g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 3243431 /Source="Nicolas_upshifts" /id="U2579" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.707292707292707" /psig="0.998001998001998" /xcortree=1789 /SigmaFactorBS="tgctgttgactaaagtatatttctgattCCATTGTAatccag ctttgatgTTACGTATAATGATTGTTAAagatactagatatcactcagattgatagta a" /listShort="yusT" /GFF_Attribute="listLong" CDS 3243491..3244378 /gene="yusT" /locus_tag="BSU_32920" /old_locus_tag="BSU32920" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:12169591, 17526699, 27965289" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12169591, 17526699, 27965289; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator of unknown specificity(LysR family)" /protein_id="NP_391171.1" /db_xref="EnsemblGenomes-Gn:BSU32920" /db_xref="EnsemblGenomes-Tr:CAB15281" /db_xref="GOA:O32186" /db_xref="InterPro:IPR000847" /db_xref="InterPro:IPR005119" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG14032" /db_xref="UniProtKB/Swiss-Prot:O32186" /translation="MESGDLRVFQMVAREGTITKAALQLGYVQSNVTARIQQLEAELG TTLFLRHNRGMTLSASGKLLLDYANKIIGLLDEASKALSSSAEPSGPLMIGCTQTTAA VRLPKLLASYYEEHPNVQLSLTTGHTQFLLDKVLRYELDGAFIGCECHHPELESYPAF EEEPVVVSAASVPDVEEAITKPILVYSTGCSYRETLEKWLRSVGVTQPVIMEFGTLEA IIGGVTAGLGISLLPRTVVQKHEAEGSIRLYPLPEALSQMKTEFIVRKDSFISSALRT FMDSFTPVKTAESQKSSLL*" gene 3243491..3244378 /gene="yusT" /locus_tag="BSU_32920" /old_locus_tag="BSU32920" CDS complement(3244398..3244685) /gene="yusU" /locus_tag="BSU_32930" /old_locus_tag="BSU32930" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 22078549" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_391172.1" /db_xref="EnsemblGenomes-Gn:BSU32930" /db_xref="EnsemblGenomes-Tr:CAB15282" /db_xref="InterPro:IPR020393" /db_xref="SubtiList:BG14033" /db_xref="UniProtKB/Swiss-Prot:O32187" /translation="MRKLLAVFSKGRWKMEQKLQEQLDGLLEKYTELLLGETNDELKE EVKQWILYTHIAKSMPPLAKHWNATYPDAKQGIKEIIQHIKELNEAHRNKQ*" gene complement(3244398..3244685) /gene="yusU" /locus_tag="BSU_32930" /old_locus_tag="BSU32930" downshifts complement(3244410) /Source="Nicolas_upshifts" /id="D1701" /incds=0 /nref=113 /ntot=280 /MaxReadThrough="1.05563" /MaxDrop="5.97768" /score="17.1690128" /energy="-13.2" /TU="NA" /idTUdmin="U2580" /TUdmin="-14" /isTUend="TRUE" CDS complement(3244710..3245537) /gene="feuV" /locus_tag="BSU_32940" /old_locus_tag="BSU32940" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:12354229, 16672620, 24847778, 25288929" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12354229, 16672620, 24847778, 25288929; Product type t: transporter" /codon_start=1 /transl_table=11 /product="iron(III)-siderophore transporter (ATP binding component)" /protein_id="NP_391173.1" /db_xref="EnsemblGenomes-Gn:BSU32940" /db_xref="EnsemblGenomes-Tr:CAB15283" /db_xref="GOA:O32188" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR017871" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG14034" /db_xref="UniProtKB/Swiss-Prot:O32188" /translation="MGMSAISTETLSLGYGDAVIIDELNLTIPKGEITVFIGSNGCGK STLLRSLARLMKPRGGSVLLEGRAIAKLPTKEVAKELAILPQGPSAPEGLTVHQLVKQ GRYPYQNWLKQWSKEDEEAVERALKATKLEDMADRAVDSLSGGQRQRAWIAMTLAQET DIILLDEPTTYLDMTHQIEILDLLFELNEKEDRTIVMVLHDLNLACRYAHHLVAIKDK RIYAEGRPEEVITCDLVQNVFSMNCQVTQDPLFGTPLCIPHGRGRCIVQEAAFTSHG* " gene complement(3244710..3245537) /gene="feuV" /locus_tag="BSU_32940" /old_locus_tag="BSU32940" downshifts complement(3244726) /Source="Nicolas_upshifts" /id="D1702" /incds=0 /nref=2 /ntot=77 /MaxReadThrough="5.36684" /MaxDrop="3.19022" /score="11.3999731" /energy="-19.8" /TU="U2580" /idTUdmin="U2581" /TUdmin=220 /isTUend="FALSE" S_feature complement(3245538..3245675) /Source="Nicolas_S_feature" /locus_tag="new_3379940_3380077_c" /HighExp="T-5.40H, Paraq, H2O2, GM-0.2, HiOs, GM 5, dia15, GM 25, T-3.40H, GM 45" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigEF" /TUshortPSig="1, 0.991" /TUlongSig="NA" /TUlongPSig="NA" /label="S1267" promotor_-10 complement(3245660..3245679) /Source="Nicolas_upshift_promotors" /id="U2580" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.463536463536464" /psig=1 /xcortree=2101 /SigmaFactorBS="taaacgtcaattatgtccataaaactaattgaaaatgATTTt caaagtcagtgtttTCTGCTACAATGAGGGATATatgaccatatcaaatggctgaata t" /listShort="S1267, yusV, yusU" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3245675) /Source="Nicolas_upshifts" /id="U2580" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.463536463536464" /psig=1 /xcortree=2101 /SigmaFactorBS="taaacgtcaattatgtccataaaactaattgaaaatgATTTt caaagtcagtgtttTCTGCTACAATGAGGGATATatgaccatatcaaatggctgaata t" /listShort="S1267, yusV, yusU" /GFF_Attribute="listLong" promotor_-35 complement(3245695..3245698) /Source="Nicolas_upshift_promotors" /id="U2580" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.463536463536464" /psig=1 /xcortree=2101 /SigmaFactorBS="taaacgtcaattatgtccataaaactaattgaaaatgATTTt caaagtcagtgtttTCTGCTACAATGAGGGATATatgaccatatcaaatggctgaata t" /listShort="S1267, yusV, yusU" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3245755..3246192) /gene="cotNW" /locus_tag="BSU_32950" /old_locus_tag="BSU32950" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1c: Function from experimental evidences in the studied genus; PubMedId: 26497467; Product type m : membrane component" /codon_start=1 /transl_table=11 /product="spore lipoprotein" /protein_id="NP_391174.1" /db_xref="EnsemblGenomes-Gn:BSU32950" /db_xref="EnsemblGenomes-Tr:CAB15284" /db_xref="InterPro:IPR025623" /db_xref="SubtiList:BG14035" /db_xref="UniProtKB/Swiss-Prot:O32189" /translation="MHLIRAAGAVCLAVVLIAGCRFNEDQHQAEGENTAVTQLKSVPY SNFSLRVSYGDGEHNRYEGIYTKNGTQEKAEIQDKLSGVNQEGEEALDEMKMILSELS VTDQMAETEVIHSVLAAFNLDSHYDHIDLKLKLKDGSIREIKK*" gene complement(3245755..3246192) /gene="cotNW" /locus_tag="BSU_32950" /old_locus_tag="BSU32950" promotor_-10 complement(3246216..3246234) /Source="Nicolas_upshift_promotors" /id="U2581" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.99100899100899" /psig="0.99100899100899" /xcortree=1192 /SigmaFactorBS="aatgccccggctttttcaattcttctcTGAATGaggatttca ttctctGGATATACCTAAAATAAATggaatcctacaggggggaaacatatgcatttga t" /listShort="yusW, S1267, yusV" /listLong="yusU" /label="promotor_-10" upshifts complement(3246222) /Source="Nicolas_upshifts" /id="U2581" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.99100899100899" /psig="0.99100899100899" /xcortree=1192 /SigmaFactorBS="aatgccccggctttttcaattcttctcTGAATGaggatttca ttctctGGATATACCTAAAATAAATggaatcctacaggggggaaacatatgcatttga t" /listShort="yusW, S1267, yusV" /listLong="yusU" promotor_-35 complement(3246250..3246255) /Source="Nicolas_upshift_promotors" /id="U2581" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.99100899100899" /psig="0.99100899100899" /xcortree=1192 /SigmaFactorBS="aatgccccggctttttcaattcttctcTGAATGaggatttca ttctctGGATATACCTAAAATAAATggaatcctacaggggggaaacatatgcatttga t" /listShort="yusW, S1267, yusV" /listLong="yusU" /label="promotor_-35" CDS complement(3246302..3247810) /gene="yusYc" /locus_tag="BSU_32960" /old_locus_tag="BSU32960" /EC_number="3.4.24.-" /function="16.11: Scavenge (Catabolism)" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function; PubMedId : 11741842; Product type e: enzyme" /pseudo /codon_start=1 /transl_table=11 /product="oligoendopeptidase; C-terminal part of YusY" /db_xref="SubtiList:BG14037" /translation="GLMNRLSADFQSSLVTLDHKLVDINQDVWNELLTKPGLRDVSYI LNERRQRVAEKLSPGKEKLIGNLAVDGYHAWSDLYNMVVGKMTIPYEENGENKQLSVG QAENMMDHQDRTVRKTVYERFRQAWESKQDIFSSTLNHLAGFRLETYKARGWENVLKE PLQINRMKKETLDTMWQVITENKKPFVQFLNRKASMLGLEKLSWYDVEAPIGSDGKVY SYDEAANIITSQFSTFGKKLSSFTEKAFRDGWIEAEDRSGKRVGGFCTSFPDSGESRI FMTFSGSASNVSTLAHELGHAFHQEAMLNVRPLNRSYAMNVAETASTFAEMIVADATV QQAETREEKLVLLEDKVQRSVAFFMNIHARFLFETRFYEERKRGVVPASRLNELMEEA QREAYCNALEEYHPLFWASKLHFHITRVPFYNFPYTFGYLFSLGIYALALEEKDTFEE KYMALLRDTASMTVEDLAMKHLGADITKRDFWENAIKLAVRDAETFLQMTES*" gene complement(3246302..3247810) /gene="yusYc" /locus_tag="BSU_32960" /old_locus_tag="BSU32960" /pseudo downshifts complement(3246323) /Source="Nicolas_upshifts" /id="D1703" /incds=0 /nref=125 /ntot=240 /MaxReadThrough="2.57385" /MaxDrop="6.5698" /score="6.83314975" /energy="-12" /TU="NA" /idTUdmin="U2582" /TUdmin="-13" /isTUend="TRUE" CDS complement(3247801..3248097) /gene="yusYn" /locus_tag="BSU_32970" /old_locus_tag="BSU32970" /function="16.11: Scavenge (Catabolism)" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function; PubMedId : 11741842; Product type e: enzyme" /pseudo /codon_start=1 /transl_table=11 /product="oligoendopeptidase; N-terminal part of YusY" /translation="MALQGVGQRWDLDSFFKGGSQSEEFKGYIEKLSQSLRAFQDRTD AFQVPESPEEAEGLTALLDLFEQTSVKLQQAGAFVACLQAQNINDQKAIEHQAS*" gene complement(3247801..3248097) /gene="yusYn" /locus_tag="BSU_32970" /old_locus_tag="BSU32970" /pseudo promotor_-10 complement(3248120..3248139) /Source="Nicolas_upshift_promotors" /id="U2582" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.708291708291708" /psig=1 /xcortree=2899 /SigmaFactorBS="actatcctgaacacgaaatgacgcctgtaatagaaatttTTA TacaataattcagaaTTGTTCTATAATAGAACGAAagaaggaaaggggttttgtgata t" /listShort="yusY, yusY" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3248136) /Source="Nicolas_upshifts" /id="U2582" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.708291708291708" /psig=1 /xcortree=2899 /SigmaFactorBS="actatcctgaacacgaaatgacgcctgtaatagaaatttTTA TacaataattcagaaTTGTTCTATAATAGAACGAAagaaggaaaggggttttgtgata t" /listShort="yusY, yusY" /GFF_Attribute="listLong" promotor_-35 complement(3248154..3248157) /Source="Nicolas_upshift_promotors" /id="U2582" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.708291708291708" /psig=1 /xcortree=2899 /SigmaFactorBS="actatcctgaacacgaaatgacgcctgtaatagaaatttTTA TacaataattcagaaTTGTTCTATAATAGAACGAAagaaggaaaggggttttgtgata t" /listShort="yusY, yusY" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 3248174..3248179 /Source="Nicolas_upshift_promotors" /id="U2583" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.975024975024975" /psig="0.998001998001998" /xcortree=2942 /SigmaFactorBS="atagaacaattctgaattattgtataaaaatttctattacag gCGTCATttcgtgttcagGATAGTACAATAGCTGTAGCagtttaataggagggttagg a" /listShort="yusZ, mrgA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3248191..3248210 /Source="Nicolas_upshift_promotors" /id="U2583" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.975024975024975" /psig="0.998001998001998" /xcortree=2942 /SigmaFactorBS="atagaacaattctgaattattgtataaaaatttctattacag gCGTCATttcgtgttcagGATAGTACAATAGCTGTAGCagtttaataggagggttagg a" /listShort="yusZ, mrgA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3248191 /Source="Nicolas_upshifts" /id="U2583" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.975024975024975" /psig="0.998001998001998" /xcortree=2942 /SigmaFactorBS="atagaacaattctgaattattgtataaaaatttctattacag gCGTCATttcgtgttcagGATAGTACAATAGCTGTAGCagtttaataggagggttagg a" /listShort="yusZ, mrgA" /GFF_Attribute="listLong" CDS 3248231..3249073 /gene="yusZ" /locus_tag="BSU_32980" /old_locus_tag="BSU32980" /EC_number="1.-.-.-" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative short-chain acyl dehydrogenase" /protein_id="NP_391177.1" /db_xref="EnsemblGenomes-Gn:BSU32980" /db_xref="EnsemblGenomes-Tr:CAB15287" /db_xref="GOA:P37959" /db_xref="InterPro:IPR002347" /db_xref="InterPro:IPR020904" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG10863" /db_xref="UniProtKB/Swiss-Prot:P37959" /translation="MNKKIAIVTGASSGFGLLAAVKLARSFFVIATSRQPEKAEQLRE LAAAHNVSDSIHITALDVTDEQSIVSFGKAVSAYAPIDLLVNNAGTAYGGFIEDVPME HFRQQFETNVFGVIHVTKTVLPYIRKHGGAKIINVSSISGLTGFPALSPYVSSKHALE GFSESLRIELLPFGIETALIEPGSYKTSIWSTSLSNFMSVPADDSAYHQYYKKILSYV QKNGEESGDPQEVADLIYQLATKQHIKNLRYPIGKGIKLTLLFRSLFPWSAWESILKK KLFS*" gene 3248231..3249073 /gene="yusZ" /locus_tag="BSU_32980" /old_locus_tag="BSU32980" promotor_-35 3248603..3248609 /Source="Nicolas_upshift_promotors" /id="U2584" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=826 /SigmaFactorBS="tgtgatccatgtgacaaaaaccgtgctgcctTACATAAgaaa gcatggcggcGCAAAGATTATAaacgtgagcagcatcagcggactgacaggattccca g" /GFF_Attribute="listShort" /listLong="mrgA" /label="promotor_-35" promotor_-10 3248624..3248635 /Source="Nicolas_upshift_promotors" /id="U2584" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=826 /SigmaFactorBS="tgtgatccatgtgacaaaaaccgtgctgcctTACATAAgaaa gcatggcggcGCAAAGATTATAaacgtgagcagcatcagcggactgacaggattccca g" /GFF_Attribute="listShort" /listLong="mrgA" /label="promotor_-10" upshifts 3248632 /Source="Nicolas_upshifts" /id="U2584" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=826 /SigmaFactorBS="tgtgatccatgtgacaaaaaccgtgctgcctTACATAAgaaa gcatggcggcGCAAAGATTATAaacgtgagcagcatcagcggactgacaggattccca g" /GFF_Attribute="listShort" /listLong="mrgA" promotor_-35 3249100..3249107 /Source="Nicolas_upshift_promotors" /id="U2585" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.465534465534466" /psig=1 /xcortree=1535 /SigmaFactorBS="aaaaagctattcagctgatctaaattataattattataattt agTATTGATTtttatttagtaTATGATATAATTAAGTCAACagatcacaaggaggacg t" /listShort="mrgA" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 3249116 /Source="Nicolas_upshifts" /id="U2585" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.465534465534466" /psig=1 /xcortree=1535 /SigmaFactorBS="aaaaagctattcagctgatctaaattataattattataattt agTATTGATTtttatttagtaTATGATATAATTAAGTCAACagatcacaaggaggacg t" /listShort="mrgA" /GFF_Attribute="listLong" promotor_-10 3249119..3249138 /Source="Nicolas_upshift_promotors" /id="U2585" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.465534465534466" /psig=1 /xcortree=1535 /SigmaFactorBS="aaaaagctattcagctgatctaaattataattattataattt agTATTGATTtttatttagtaTATGATATAATTAAGTCAACagatcacaaggaggacg t" /listShort="mrgA" /GFF_Attribute="listLong" /label="promotor_-10" CDS 3249163..3249624 /gene="mrgA" /locus_tag="BSU_32990" /old_locus_tag="BSU32990" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:12029044, 8709848, 21057011, 22194458, 24123749, 28434086" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12029044, 8709848, 21057011, 22194458, 24123749, 28434086; Product type f : factor" /codon_start=1 /transl_table=11 /product="metalloregulation DNA-binding stress protein" /protein_id="NP_391178.1" /db_xref="EnsemblGenomes-Gn:BSU32990" /db_xref="EnsemblGenomes-Tr:CAB15288" /db_xref="GOA:P37960" /db_xref="InterPro:IPR002177" /db_xref="InterPro:IPR008331" /db_xref="InterPro:IPR009078" /db_xref="InterPro:IPR012347" /db_xref="InterPro:IPR023188" /db_xref="PDB:2CHP" /db_xref="SubtiList:BG10864" /db_xref="UniProtKB/Swiss-Prot:P37960" /translation="MKTENAKTNQTLVENSLNTQLSNWFLLYSKLHRFHWYVKGPHFF TLHEKFEELYDHAAETVDTIAERLLAIGGQPVATVKEYTEHASITDGGNETSASEMVQ ALVNDYKQISSESKFVIGLAEENQDNATADLFVGLIEEVEKQVWMLSSYLG*" gene 3249163..3249624 /gene="mrgA" /locus_tag="BSU_32990" /old_locus_tag="BSU32990" downshifts 3249600 /Source="Nicolas_upshifts" /id="D1704" /incds=0 /nref=234 /ntot=274 /MaxReadThrough="1.7919" /MaxDrop="8.26581" /score="36.5549876" /energy="-13.3" /TU="NA" /idTUdmin="U2583" /TUdmin=0 /isTUend="TRUE" CDS complement(3249668..3251044) /gene="htrB" /locus_tag="BSU_33000" /old_locus_tag="BSU33000" /function="16.8: Protect" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:11133960, 11717295, 16033468, 16911528, 22307758, 23937099, 24362423" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11133960, 11717295, 16033468, 16911528, 22307758, 23937099, 24362423; Product type f: factor" /codon_start=1 /transl_table=11 /product="protease-associated chaperone for the extracytoplasmic folding and quality control of exported proteins" /protein_id="NP_391180.2" /db_xref="EnsemblGenomes-Gn:BSU33000" /db_xref="EnsemblGenomes-Tr:CAB15290" /db_xref="GOA:Q9R9I1" /db_xref="InterPro:IPR001478" /db_xref="InterPro:IPR001940" /db_xref="InterPro:IPR009003" /db_xref="InterPro:IPR036034" /db_xref="SubtiList:BG14155" /db_xref="UniProtKB/Swiss-Prot:Q9R9I1" /translation="MDYRRDGQNDQHQTEPSHTEQQNTENQKLIGHSEQELLDAPVSY EAGRQETASALEMEKQETAVKKEKKRRAAWLSPILGGIIGGGLMLGIAPYLPSDQNQA TETASANKQVQSDNFTTAPITNASNIADMVEDLEPTIVGISNIQTSQNNTFGTGGGSS SESESGTGSGVIFKKDSDKAYIITNNHVVEGANKLTVTLYNGETETAKLVGSDTITDL AVLEISGKNVKKVASFGDSSQLRTGEKVIAIGNPLGQQFSGTVTQGIISGLNRTIDVD TTQGTVEMNVLQTDAAINPGNSGGPLINASGQVIGINSLKVSESGVESLGFAIPSNDV EPIVDQLLQNGKVDRPFLGVQMIDMSQVPETYQENTLGLFGDQLGKGVYVKEVQANSP AEKAGIKSEDVIVKLNGKDVESSADIRQILYKDLKVGDKTTIQVLRKGKTKTLNATLT KQTESSSS*" gene complement(3249668..3251044) /gene="htrB" /locus_tag="BSU_33000" /old_locus_tag="BSU33000" downshifts complement(3249676) /Source="Nicolas_upshifts" /id="D1705" /incds=0 /nref=206 /ntot=257 /MaxReadThrough="1.84997" /MaxDrop="6.39104" /score="17.1953741" /energy="-11.2" /TU="U2586" /idTUdmin="U2586" /TUdmin="-22" /isTUend="TRUE" S_feature complement(3251045..3251216) /Source="Nicolas_S_feature" /locus_tag="new_3385447_3385618_c" /HighExp="SMMPr, T-0.40H, T-1.10H, M9-tran, T-1.40H, T1.0H, T0.30H, T1.30H, Etha, M/G" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.67259999999999998" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="SigA" /TUlongPSig=1 /label="S1268" promotor_-10 complement(3251197..3251216) /Source="Nicolas_upshift_promotors" /id="U2586" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.883116883116883" /psig=1 /xcortree=1764 /SigmaFactorBS="acggcaggcaattttcataatttcacatattcttttcatttt TATCCCACaatgtttgttTATGATATGGTTAAGGGAAGaaaggaagagaaaaagagcg a" /listShort="S1268, htrB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3251216) /Source="Nicolas_upshifts" /id="U2586" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.883116883116883" /psig=1 /xcortree=1764 /SigmaFactorBS="acggcaggcaattttcataatttcacatattcttttcatttt TATCCCACaatgtttgttTATGATATGGTTAAGGGAAGaaaggaagagaaaaagagcg a" /listShort="S1268, htrB" /GFF_Attribute="listLong" promotor_-35 complement(3251227..3251234) /Source="Nicolas_upshift_promotors" /id="U2586" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.883116883116883" /psig=1 /xcortree=1764 /SigmaFactorBS="acggcaggcaattttcataatttcacatattcttttcatttt TATCCCACaatgtttgttTATGATATGGTTAAGGGAAGaaaggaagagaaaaagagcg a" /listShort="S1268, htrB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(3251277..3251296) /Source="Nicolas_upshift_promotors" /id="U2588" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.988011988011988" /psig=1 /xcortree=2391 /SigmaFactorBS="cctcatcttcaactagataaatggtgtatgacaaggcTCTTC ACAtcctttcaacgtcaTTATAAACTAGTTTTAACATacggcaggcaattttcataat t" /GFF_Attribute="listShort" /listLong="S1268, htrB" /label="promotor_-10" misc_feature 3251287..3251306 /Source="Nicolas_upshift_promotors" /id="U2587" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.761238761238761" /psig="0.994005994005994" /xcortree=2013 /SigmaFactorBS="gggataaaaatgaaaagaatatgtgaaattatgaaaattgcc tgccgtatgttaaaacTAGTTTATAATGACGTTGAAaggatgtgaagagccttgtcat a" /listShort="cssR, cssS" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 3251289 /Source="Nicolas_upshifts" /id="U2587" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.761238761238761" /psig="0.994005994005994" /xcortree=2013 /SigmaFactorBS="gggataaaaatgaaaagaatatgtgaaattatgaaaattgcc tgccgtatgttaaaacTAGTTTATAATGACGTTGAAaggatgtgaagagccttgtcat a" /listShort="cssR, cssS" /GFF_Attribute="listLong" upshifts complement(3251295) /Source="Nicolas_upshifts" /id="U2588" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.988011988011988" /psig=1 /xcortree=2391 /SigmaFactorBS="cctcatcttcaactagataaatggtgtatgacaaggcTCTTC ACAtcctttcaacgtcaTTATAAACTAGTTTTAACATacggcaggcaattttcataat t" /GFF_Attribute="listShort" /listLong="S1268, htrB" S_feature complement(3251297..3252360) /Source="Nicolas_S_feature" /locus_tag="new_3385699_3386762_c" /HighExp="T1.0H, T0.30H, T1.30H, C30, T2.0H, G135, G180, T2.30H, ferm, G150" /AntisenseName="cssR" /AntisenseCor="0.115381389160342" /AntisenseRegPval="-1.2" /CDS_PredictionProba="NA" /TUshortSig="NA" /TUshortPSig="NA" /TUlongSig="NA" /TUlongPSig="NA" /label="S1269" promotor_-35 complement(3251311..3251318) /Source="Nicolas_upshift_promotors" /id="U2588" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.988011988011988" /psig=1 /xcortree=2391 /SigmaFactorBS="cctcatcttcaactagataaatggtgtatgacaaggcTCTTC ACAtcctttcaacgtcaTTATAAACTAGTTTTAACATacggcaggcaattttcataat t" /GFF_Attribute="listShort" /listLong="S1268, htrB" /label="promotor_-35" CDS 3251322..3251999 /gene="cssR" /locus_tag="BSU_33010" /old_locus_tag="BSU33010" /function="16.8: Protect" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:11555295, 11717295, 12270824, 15856219, 16911528, 17586671, 27026185" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11555295, 11717295, 12270824, 15856219, 16911528, 17586671, 27026185; Product type r: regulator" /codon_start=1 /transl_table=11 /product="folding stress-sensitive two-component response regulator" /protein_id="NP_391181.1" /db_xref="EnsemblGenomes-Gn:BSU33010" /db_xref="EnsemblGenomes-Tr:CAB15291" /db_xref="GOA:O32192" /db_xref="InterPro:IPR001789" /db_xref="InterPro:IPR001867" /db_xref="InterPro:IPR011006" /db_xref="InterPro:IPR016032" /db_xref="InterPro:IPR036388" /db_xref="SubtiList:BG14131" /db_xref="UniProtKB/Swiss-Prot:O32192" /translation="MSYTIYLVEDEDNLNELLTKYLENEGWNITSFTKGEDARKKMTP SPHLWILDIMLPDTDGYTLIKEIKAKDPDVPVIFISARDADIDRVLGLELGSNDYISK PFLPRELIIRVQKLLQLVYKEAPPVQKNEIAVSSYRVAEDAREVYDENGNIINLTSKE FDLLLLFIHHKGHPYSREDILLKVWGHDYFGTDRVVDDLVRRLRRKMPELKVETIYGF GYRMMSS*" gene 3251322..3251999 /gene="cssR" /locus_tag="BSU_33010" /old_locus_tag="BSU33010" CDS 3251996..3253351 /gene="cssS" /locus_tag="BSU_33020" /old_locus_tag="BSU33020" /function="16.3: Control" /function="16.12: Sense" /experiment="publication(s) with functional evidences, PMID:11555295, 11717295, 12270824, 15856219, 16911528, 17586671, 27026185" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11555295, 11717295, 12270824, 15856219, 16911528, 17586671, 27026185; Product type rc: receptor" /codon_start=1 /transl_table=11 /product="folding stress-sensitive two-component sensor histidine kinase" /protein_id="NP_391182.2" /db_xref="EnsemblGenomes-Gn:BSU33020" /db_xref="EnsemblGenomes-Tr:CAB15292" /db_xref="GOA:O32193" /db_xref="InterPro:IPR003594" /db_xref="InterPro:IPR003660" /db_xref="InterPro:IPR003661" /db_xref="InterPro:IPR004358" /db_xref="InterPro:IPR005467" /db_xref="InterPro:IPR036097" /db_xref="InterPro:IPR036890" /db_xref="SubtiList:BG14132" /db_xref="UniProtKB/Swiss-Prot:O32193" /translation="MKNKPLAFQIWVVISGILLAISILLLVLFSNTLRDFFTNETYTT IENEQHVLTEYRLPGSIERRYYSEEATAPTTVRSVQHVLLPENEEASSDKDLSILSSS FIHKVYKLADKQEAKKKRYSADVNGEKVFFVIKKGLSVNGQSAMMLSYALDSYRDDLA YTLFKQLLFIIAVVILLSWIPAIWLAKYLSRPLVSFEKHVKRISEQDWDDPVKVDRKD EIGKLGHTIEEMRQKLVQKDETERTLLQNISHDLKTPVMVIRGYTQSIKDGIFPKGDL ENTVDVIECEALKLEKKIKDLLYLTKLDYLAKQKVQHDMFSIVEVTEEVIERLKWARK ELSWEIDVEEDILMPGDPEQWNKLLENILENQIRYAETKIEISMKQDDRNIVITIKND GPHIEDEMLSSLYEPFNKGKKGEFGIGLSIVKRILTLHKASISIENDKTGVTYRIAVP K*" gene 3251996..3253351 /gene="cssS" /locus_tag="BSU_33020" /old_locus_tag="BSU33020" S_feature complement(3252450..3253378) /Source="Nicolas_S_feature" /locus_tag="new_3386852_3387780_c" /HighExp="T1.0H, T0.30H, T1.30H, T2.0H, T2.30H, ferm, C30, LPhT, T-1.10H, Lbstat" /AntisenseName="cssS" /AntisenseCor="0.27217686232372901" /AntisenseRegPval="-5.2" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA, SigD, SigH, SigA" /TUshortPSig="1, 0.869, 1, 0.999, 0.996" /TUlongSig="NA" /TUlongPSig="NA" /label="S1270" downshifts 3253319 /Source="Nicolas_upshifts" /id="D1706" /incds=0 /nref=61 /ntot=203 /MaxReadThrough="0.95076" /MaxDrop="4.47937" /score="13.0972324" /energy="-9.7" /TU="NA" /idTUdmin="U2587" /TUdmin=1 /isTUend="TRUE" CDS complement(3253379..3253543) /gene="spxO" /locus_tag="BSU_33029" /old_locus_tag="BSU33029" /experiment="publication(s) with functional evidences, PMID:21378193" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 21378193; Product type r: regulator" /codon_start=1 /transl_table=11 /product="regulator of SpxA degradation" /protein_id="YP_003097785.1" /db_xref="EnsemblGenomes-Gn:BSU33029" /db_xref="EnsemblGenomes-Tr:CAX52691" /db_xref="GOA:O32302" /db_xref="UniProtKB/Swiss-Prot:O32302" /translation="MRELDEMISRLRNRGIKVEKVKYPKQTLSEKKWVHQCKQPLKTN YRDFNGYSFT*" gene complement(3253379..3253543) /gene="spxO" /locus_tag="BSU_33029" /old_locus_tag="BSU33029" promotor_-35 3253567..3253574 /Source="Nicolas_upshift_promotors" /id="U2589" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.74925074925075" /psig=1 /xcortree=1903 /SigmaFactorBS="tctcattctagattcaccctttcgcttgaGCTTTGACcattc ggtcatctCAATTTATAATATAAATAATacatgataaaaaaacaagttacaataaggt t" /listShort="S1271, yuxN" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3253588..3253607 /Source="Nicolas_upshift_promotors" /id="U2589" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.74925074925075" /psig=1 /xcortree=1903 /SigmaFactorBS="tctcattctagattcaccctttcgcttgaGCTTTGACcattc ggtcatctCAATTTATAATATAAATAATacatgataaaaaaacaagttacaataaggt t" /listShort="S1271, yuxN" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-10 complement(3253592..3253611) /Source="Nicolas_upshift_promotors" /id="U2590" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.477522477522478" /psig=1 /xcortree=3229 /SigmaFactorBS="tatagtcacaccgtctgttataaaattaaccttATTGTAACt tgtttttttatcATGTATTATTTATATTATAAattgagatgaccgaatggtcaaagct c" /listShort="yuzO, S1270" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 3253598..3253710 /Source="Nicolas_S_feature" /locus_tag="new_3388000_3388112" /HighExp="dia5, Diami, T0.30H, T-0.40H, T0.0H, dia15, Salt, ferm, G135, T-1.40H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1271" upshifts 3253598 /Source="Nicolas_upshifts" /id="U2589" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.74925074925075" /psig=1 /xcortree=1903 /SigmaFactorBS="tctcattctagattcaccctttcgcttgaGCTTTGACcattc ggtcatctCAATTTATAATATAAATAATacatgataaaaaaacaagttacaataaggt t" /listShort="S1271, yuxN" /GFF_Attribute="listLong" upshifts complement(3253605) /Source="Nicolas_upshifts" /id="U2590" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.477522477522478" /psig=1 /xcortree=3229 /SigmaFactorBS="tatagtcacaccgtctgttataaaattaaccttATTGTAACt tgtttttttatcATGTATTATTTATATTATAAattgagatgaccgaatggtcaaagct c" /listShort="yuzO, S1270" /GFF_Attribute="listLong" S_feature complement(3253607..3253885) /Source="Nicolas_S_feature" /locus_tag="new_3388009_3388287_c" /HighExp="Etha, Gly, S2, Glucon, Pyr, G/S, S1, Lbstat, Cold, HiTm" /AntisenseName="yuxN" /AntisenseCor="-0.128326996122899" /AntisenseRegPval="-1.5" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigD, SigH, SigA" /TUshortPSig="0.869, 1, 0.999, 0.996" /TUlongSig="NA" /TUlongPSig="NA" /label="S1272" promotor_-35 complement(3253625..3253632) /Source="Nicolas_upshift_promotors" /id="U2590" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.477522477522478" /psig=1 /xcortree=3229 /SigmaFactorBS="tatagtcacaccgtctgttataaaattaaccttATTGTAACt tgtttttttatcATGTATTATTTATATTATAAattgagatgaccgaatggtcaaagct c" /listShort="yuzO, S1270" /GFF_Attribute="listLong" /label="promotor_-35" CDS 3253711..3254586 /gene="yuxN" /locus_tag="BSU_33030" /old_locus_tag="BSU33030" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative transcriptional regulator" /protein_id="NP_391183.1" /db_xref="EnsemblGenomes-Gn:BSU33030" /db_xref="EnsemblGenomes-Tr:CAB15293" /db_xref="GOA:P40950" /db_xref="InterPro:IPR001647" /db_xref="InterPro:IPR009057" /db_xref="InterPro:IPR023772" /db_xref="SubtiList:BG11072" /db_xref="UniProtKB/Swiss-Prot:P40950" /translation="MKEKEKLIIETALKLFAQKGYNSTSVQEIAKECKISKGAFYIYF PSKEALLLSMLNYYYDKTFTRILNIKTKGDSPRTAYRKQLTVLYENILEHKDFISMQL KEGSLPYTEEVEQCAKKIRQSSLQFHIDSLLNIYGKKAEPYTAELCFLIEGISQIYLE CMILLGYTVKPSQLADIIMNRIDDMVKGMSERNDKPFITLEEASSLFGPLTHGRPDPL TESIVKSLRDKINSLNTNSSLELSESLDILEAEMKKKTPKLAIIKGMIHNLTESEALA KDAEQLKYLLKQQHI*" gene 3253711..3254586 /gene="yuxN" /locus_tag="BSU_33030" /old_locus_tag="BSU33030" promotor_-10 complement(3253875..3253894) /Source="Nicolas_upshift_promotors" /id="U2591" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.627372627372627" /psig="0.869130869130869" /xcortree=103 /SigmaFactorBS="ccgttctggggctgtcgcccttcgttttaaTATTTAAAattc gggtaaacgTTTTATCATAATAGTAGTTCagcatagagagaagaagcgcttctttcga a" /listShort="S1272, yuzO, S1270" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3253885) /Source="Nicolas_upshifts" /id="U2591" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.627372627372627" /psig="0.869130869130869" /xcortree=103 /SigmaFactorBS="ccgttctggggctgtcgcccttcgttttaaTATTTAAAattc gggtaaacgTTTTATCATAATAGTAGTTCagcatagagagaagaagcgcttctttcga a" /listShort="S1272, yuzO, S1270" /GFF_Attribute="listLong" S_feature complement(3253887..3254428) /Source="Nicolas_S_feature" /locus_tag="new_3388289_3388830_c" /HighExp="LBGstat, Cold, S2, Glucon, S1, Pyr, G/S, C30, GM 10, GM-0.1" /AntisenseName="yuxN" /AntisenseCor="-0.341746670828522" /AntisenseRegPval="-8.1" /CDS_PredictionProba="NA" /TUshortSig="SigD, SigH, SigA" /TUshortPSig="1, 0.999, 0.996" /TUlongSig="NA" /TUlongPSig="NA" /label="S1273" promotor_-35 complement(3253908..3253915) /Source="Nicolas_upshift_promotors" /id="U2591" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.627372627372627" /psig="0.869130869130869" /xcortree=103 /SigmaFactorBS="ccgttctggggctgtcgcccttcgttttaaTATTTAAAattc gggtaaacgTTTTATCATAATAGTAGTTCagcatagagagaagaagcgcttctttcga a" /listShort="S1272, yuzO, S1270" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(3254420..3254438) /Source="Nicolas_upshift_promotors" /id="U2592" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2843 /SigmaFactorBS="ccagcttcggtgtttttttcttcatttctgCTTCAAGTatgt ccaagctcTCCGATAATTCAAGAGAGGagtttgtgtttaagctgttaattttgtcacg t" /listShort="S1273, S1272, yuzO, S1270" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3254428) /Source="Nicolas_upshifts" /id="U2592" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2843 /SigmaFactorBS="ccagcttcggtgtttttttcttcatttctgCTTCAAGTatgt ccaagctcTCCGATAATTCAAGAGAGGagtttgtgtttaagctgttaattttgtcacg t" /listShort="S1273, S1272, yuzO, S1270" /GFF_Attribute="listLong" S_feature complement(3254430..3254559) /Source="Nicolas_S_feature" /locus_tag="new_3388832_3388961_c" /HighExp="S2, S1, G/S, Glucon, Pyr, T3.30H, M9-stat, BT, Cold, T4.0H" /AntisenseName="yuxN" /AntisenseCor="-0.30886083736579201" /AntisenseRegPval="-6.6" /CDS_PredictionProba="NA" /TUshortSig="SigH, SigA" /TUshortPSig="0.999, 0.996" /TUlongSig="NA" /TUlongPSig="NA" /label="S1274" promotor_-35 complement(3254451..3254458) /Source="Nicolas_upshift_promotors" /id="U2592" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2843 /SigmaFactorBS="ccagcttcggtgtttttttcttcatttctgCTTCAAGTatgt ccaagctcTCCGATAATTCAAGAGAGGagtttgtgtttaagctgttaattttgtcacg t" /listShort="S1273, S1272, yuzO, S1270" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 3254561 /Source="Nicolas_upshifts" /id="D1707" /incds=0 /nref=30 /ntot=182 /MaxReadThrough="3.14099" /MaxDrop="3.7614" /score="-3.47814442" /energy="-13.6" /TU="NA" /idTUdmin="U2589" /TUdmin="-11" /isTUend="TRUE" downshifts complement(3254604) /Source="Nicolas_upshifts" /id="D1708" /incds=0 /nref=1 /ntot=31 /MaxReadThrough="5.30537" /MaxDrop="3.29426" /score="-2.73895091" /energy="-13.6" /TU="U2593,U2594" /idTUdmin="U2591" /TUdmin="-1584" /isTUend="FALSE" CDS complement(3254622..3256010) /gene="fumC" /locus_tag="BSU_33040" /old_locus_tag="BSU33040" /EC_number="4.2.1.2" /function="16.2: Construct biomass (Anabolism)" /function="16.10: Respire" /function="16.7: Manage energy" /experiment="publication(s) with functional evidences, PMID:2509422, 3130545, 3923430, 9647666, 22914898, 28032445" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 2509422, 3130545, 3923430, 9647666, 22914898, 28032445; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="fumarate hydratase" /protein_id="NP_391184.1" /db_xref="EnsemblGenomes-Gn:BSU33040" /db_xref="EnsemblGenomes-Tr:CAB15294" /db_xref="GOA:P07343" /db_xref="InterPro:IPR000362" /db_xref="InterPro:IPR005677" /db_xref="InterPro:IPR008948" /db_xref="InterPro:IPR018951" /db_xref="InterPro:IPR020557" /db_xref="InterPro:IPR022761" /db_xref="InterPro:IPR024083" /db_xref="SubtiList:BG10384" /db_xref="UniProtKB/Swiss-Prot:P07343" /translation="MEYRIERDTMGEVKVPADKFWGAQTQRSKENFKIGSEKMPMRVV KAFAILKRSTALANKRLGNLDAEKAEAIAAVCDDVLKGKYDDNFPLVVWQTGSGTQSN MNMNEVVANRATALLKEKNSDQTIHPNDDVNRSQSSNDTFPTAMHVAAVLAVYEQLVP ALDQLRNTLDEKAKAYNDIVKIGRTHLQDATPLTLGQEISGWVHMLDRSKEMILEATD KMRALAIGGTAVGTGINAHPEFGELVSEEITKLTGQTFSSSPNKFHALTSHDEITYAH GALKALAADLMKIANDVRWLASGPRCGIGEIVIPENEPGSSIMPGKVNPTQSEALTMI AAQIMGNDATIGFAASQGNFELNVFKPVIIYNFLQSVQLLSDGMNSFHDKCAVGIEPN KETIQENLSNSLMLVTALNPHIGYENAAKIAKLAHKEGLTLKEAALKLELLTEEQFNE MVKPEDMVKPKA*" gene complement(3254622..3256010) /gene="fumC" /locus_tag="BSU_33040" /old_locus_tag="BSU33040" upshifts complement(3256034) /Source="Nicolas_upshifts" /id="U2593" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=3195 /SigmaFactorBS="gccaagatcgaaaaataaAAAGGATTTtttgtgtcatTGGCG AATTATGATCTATTgaagcaaccgttatggagggatacataaatggaatacagaattg a" /listShort="fumC, S1274, S1273, S1272, yuzO, S1270" /GFF_Attribute="listLong" promotor_-10 complement(3256039..3256057) /Source="Nicolas_upshift_promotors" /id="U2593" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=3195 /SigmaFactorBS="gccaagatcgaaaaataaAAAGGATTTtttgtgtcatTGGCG AATTATGATCTATTgaagcaaccgttatggagggatacataaatggaatacagaattg a" /listShort="fumC, S1274, S1273, S1272, yuzO, S1270" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 complement(3256068..3256076) /Source="Nicolas_upshift_promotors" /id="U2593" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=3195 /SigmaFactorBS="gccaagatcgaaaaataaAAAGGATTTtttgtgtcatTGGCG AATTATGATCTATTgaagcaaccgttatggagggatacataaatggaatacagaattg a" /listShort="fumC, S1274, S1273, S1272, yuzO, S1270" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3256077..3256262) /gene="yvzF" /locus_tag="BSU_33049" /old_locus_tag="BSU33049" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 22720735" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="YP_003097786.1" /db_xref="EnsemblGenomes-Gn:BSU33049" /db_xref="EnsemblGenomes-Tr:CAX52692" /db_xref="InterPro:IPR025088" /db_xref="UniProtKB/Swiss-Prot:C0H3R3" /translation="MAQVRLAGKQEEIEQLIRSFEQHYDVSYTSKEYGRTNPKYKYSK DSRVYLELKLKSAKIEK*" gene complement(3256077..3256262) /gene="yvzF" /locus_tag="BSU_33049" /old_locus_tag="BSU33049" downshifts 3256266 /Source="Nicolas_upshifts" /id="D1709" /incds=0 /nref=4 /ntot=100 /MaxReadThrough="1.13377" /MaxDrop="4.4478" /score="-3.47814442" /energy="-13.6" /TU="NA" /idTUdmin="U2595" /TUdmin="-748" /isTUend="FALSE" promotor_-10 complement(3256306..3256325) /Source="Nicolas_upshift_promotors" /id="U2594" /multdbtbs="SigA,SigA" /comp="M4" /sig="SigA" /pcomp="0.566433566433566" /psig="0.996003996003996" /xcortree=2565 /SigmaFactorBS="atgaggtcacctcttatccaaaaccttagtagaggtTATCtt ttcctgttaaaaaAATGATATACTGTGTTAGAGtatttcatggagtaagtttttttat g" /listShort="yvzF, fumC, S1274, S1273, S1272, yuzO, S1270" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 3256315..3256321 /Source="Nicolas_upshift_promotors" /id="U2595" /multdbtbs="SigF,SigG" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=904 /SigmaFactorBS="ttcataaaaaaacttactccatgaaatactctaacacAGTAT ATcatttttttaacaGGAAAAGATAACctctactaaggttttggataagaggtgacct c" /listShort="gerAA" /GFF_Attribute="listLong" /label="promotor_-35" upshifts complement(3256320) /Source="Nicolas_upshifts" /id="U2594" /multdbtbs="SigA,SigA" /comp="M4" /sig="SigA" /pcomp="0.566433566433566" /psig="0.996003996003996" /xcortree=2565 /SigmaFactorBS="atgaggtcacctcttatccaaaaccttagtagaggtTATCtt ttcctgttaaaaaAATGATATACTGTGTTAGAGtatttcatggagtaagtttttttat g" /listShort="yvzF, fumC, S1274, S1273, S1272, yuzO, S1270" /GFF_Attribute="listLong" promotor_-10 3256335..3256346 /Source="Nicolas_upshift_promotors" /id="U2595" /multdbtbs="SigF,SigG" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=904 /SigmaFactorBS="ttcataaaaaaacttactccatgaaatactctaacacAGTAT ATcatttttttaacaGGAAAAGATAACctctactaaggttttggataagaggtgacct c" /listShort="gerAA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3256338 /Source="Nicolas_upshifts" /id="U2595" /multdbtbs="SigF,SigG" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=904 /SigmaFactorBS="ttcataaaaaaacttactccatgaaatactctaacacAGTAT ATcatttttttaacaGGAAAAGATAACctctactaaggttttggataagaggtgacct c" /listShort="gerAA" /GFF_Attribute="listLong" promotor_-35 complement(3256341..3256344) /Source="Nicolas_upshift_promotors" /id="U2594" /multdbtbs="SigA,SigA" /comp="M4" /sig="SigA" /pcomp="0.566433566433566" /psig="0.996003996003996" /xcortree=2565 /SigmaFactorBS="atgaggtcacctcttatccaaaaccttagtagaggtTATCtt ttcctgttaaaaaAATGATATACTGTGTTAGAGtatttcatggagtaagtttttttat g" /listShort="yvzF, fumC, S1274, S1273, S1272, yuzO, S1270" /GFF_Attribute="listLong" /label="promotor_-35" CDS 3256380..3257828 /gene="gerAA" /locus_tag="BSU_33050" /old_locus_tag="BSU33050" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:11418573, 15774895, 16740944, 28605069" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11418573, 15774895, 16740944, 28605069; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="component of the GerA germination receptor" /protein_id="NP_391185.2" /db_xref="EnsemblGenomes-Gn:BSU33050" /db_xref="EnsemblGenomes-Tr:CAB15295" /db_xref="GOA:P07868" /db_xref="InterPro:IPR004995" /db_xref="SubtiList:BG10385" /db_xref="UniProtKB/Swiss-Prot:P07868" /translation="MEQTEFKEYIHDNLALVLPKLKENDDLVKNKKMLANGLVFYYLY FSEMTDENKVSEAIKTLIKDEETLTLDQVKKRLDQLDARPVETAKKTIESILNGNCAV FINGLDKAYILTTGKKKTRSLTEPTTEKVVRGPKVAFVEDIDTNLALIRQRTSHPKLI TKKIMIGENKLKPAAIMYIEGKAKKSVIKEVKARLKNIQLEDIQDSGTLEELIEDNKY SPFPQIQNTERPDKVSSALFNGRVAILVDSSPFVLLVPVSLGILMQSPDDYYERWISA SLIRSLRFASIFITLFLSSIYITLVSFHQGLLPTALAVTISANRENVPFPPIFEALLM EVTIELLREAGLRLPNPLGQTIGLVGGVVIGQAAVEANLVSSILVIVVSVIALASFTV PQYGMGLSFRVLRFISMFSAAILGLYGIILFMLVVYTHLTRQTSFGSPYFSPNGFFSL KNTDDSIIRLPIKNKPKEVNNPNEPKTDSTET*" gene 3256380..3257828 /gene="gerAA" /locus_tag="BSU_33050" /old_locus_tag="BSU33050" S_feature complement(3257376..3260019) /Source="Nicolas_S_feature" /locus_tag="new_3391778_3394421_c" /HighExp="Cold, H2O2, G135, G180, Paraq, G150, Oxctl, T-5.40H, LBGstat, T-4.40H" /AntisenseName="gerAC" /AntisenseCor="-9.7163861003102397E-2" /AntisenseRegPval="-1" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S1275" CDS 3257797..3258894 /gene="gerAB" /locus_tag="BSU_33060" /old_locus_tag="BSU33060" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:15774895, 15849754, 16740944, 16850406, 28605069" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15774895, 15849754, 16740944, 16850406, 28605069; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="component of the germination receptor GerA; putative transporter" /protein_id="NP_391186.1" /db_xref="EnsemblGenomes-Gn:BSU33060" /db_xref="EnsemblGenomes-Tr:CAB15296" /db_xref="GOA:P07869" /db_xref="InterPro:IPR004761" /db_xref="SubtiList:BG10386" /db_xref="UniProtKB/Swiss-Prot:P07869" /translation="MSQKQTPLKLNTFQGISIVANTMLGAGLLTLPRALTTKANTPDG WITLILEGFIFIFFIYLNTLIQKKHQYPSLFEYLKEGLGKWIGSIIGLLICGYFLGVA SFETRAMAEMVKFFLLERTPIQVIILTFICCGIYLMVGGLSDVSRLFPFYLTVTIIIL LIVFGISFKIFDINNLRPVLGEGLGPIANSLTVVSISFLGMEVMLFLPEHMKKKKYTF RYASLGFLIPIILYILTYIIVVGALTAPEVKTLIWPTISLFQSFELKGIFIERFESFL LVVWIIQFFTTFVIYGYFAANGLKKTFGLSTKTSMVIIGITVFYFSLWPDDANQVMMY SDYLGYIFVSLFLLPFILFFIVALKRRITTK*" gene 3257797..3258894 /gene="gerAB" /locus_tag="BSU_33060" /old_locus_tag="BSU33060" CDS 3258891..3260012 /gene="gerAC" /locus_tag="BSU_33070" /old_locus_tag="BSU33070" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:11418573, 15774895, 16740944, 28605069" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11418573, 15774895, 16740944, 28605069; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="component of the germination receptor GerA" /protein_id="NP_391187.1" /db_xref="EnsemblGenomes-Gn:BSU33070" /db_xref="EnsemblGenomes-Tr:CAB15297" /db_xref="GOA:P07870" /db_xref="InterPro:IPR008844" /db_xref="SubtiList:BG10387" /db_xref="UniProtKB/Swiss-Prot:P07870" /translation="MKIRILCMFICTLLLSGCWDSENIEELSLVIGIGLDKPDDENLE LTQQILVPKIISAKEGSSSDPTQLSITKGKTVHQMMRTSALKHKPTFSQHLRLILLSK SVIADQIGMDAIINQFVRDNGTRRSSYVFITNGRTKDIFNMNDEGEPASNVIYDLTEN NKVTIRTMEPVTLGEISEHLTSDDSFLIPHVGKENGKLAINGASIIKNKLWHRDLTPI EVQNISLFSGTVEGGVIDLKRDGHLFSYEVYSSNRKIKTAYKDGKFKFTVTRNIEGRL SEDWNPNEDSFKDSYIKSIEKTVEKRVHETVTSFITEKLQKEIKADVTGLGNEVRIHY PQKWKKISRKWDDDYFSNAEIDYRVNVIVRDFGTKGANK*" gene 3258891..3260012 /gene="gerAC" /locus_tag="BSU_33070" /old_locus_tag="BSU33070" CDS complement(3260020..3260655) /gene="liaR" /locus_tag="BSU_33080" /old_locus_tag="BSU33080" /function="16.6: Maintain" /function="16.3: Control" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:11717295, 15273097, 16816187, 17660417, 17921301, 23279150, 23326432, 24666271" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11717295, 15273097, 16816187, 17660417, 17921301, 23279150, 23326432, 24666271; Product type r: regulator" /codon_start=1 /transl_table=11 /product="two-component response regulator [YvqE] responding to cell wall stress" /protein_id="NP_391188.1" /db_xref="EnsemblGenomes-Gn:BSU33080" /db_xref="EnsemblGenomes-Tr:CAB15298" /db_xref="GOA:O32197" /db_xref="InterPro:IPR000792" /db_xref="InterPro:IPR001789" /db_xref="InterPro:IPR011006" /db_xref="InterPro:IPR016032" /db_xref="InterPro:IPR036388" /db_xref="SubtiList:BG14133" /db_xref="UniProtKB/Swiss-Prot:O32197" /translation="MIRVLLIDDHEMVRMGLAAFLEAQPDIEVIGEASDGSEGVRLAV ELSPDVILMDLVMEGMDGIEATKQICRELSDPKIIVLTSFIDDDKVYPVIEAGALSYL LKTSKAAEIADAIRAASKGEPKLESKVAGKVLSRLRHSGENALPHESLTKRELEILCL IAEGKTNKEIGEELFITIKTVKTHITNILSKLDVSDRTQAAVYAHRNHLVN*" gene complement(3260020..3260655) /gene="liaR" /locus_tag="BSU_33080" /old_locus_tag="BSU33080" CDS complement(3260633..3261715) /gene="liaS" /locus_tag="BSU_33090" /old_locus_tag="BSU33090" /function="16.12: Sense" /function="16.8: Protect" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:11717295, 15273097, 16816187, 17660417, 17921301, 23279150, 23326432, 24666271" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11717295, 15273097, 16816187, 17660417, 17921301, 23279150, 23326432, 24666271; Product type rc: receptor" /codon_start=1 /transl_table=11 /product="two-component sensor histidine kinase [LiaR(YvqC)] sensing cell wall stress" /protein_id="NP_391189.1" /db_xref="EnsemblGenomes-Gn:BSU33090" /db_xref="EnsemblGenomes-Tr:CAB15299" /db_xref="GOA:O32198" /db_xref="InterPro:IPR003594" /db_xref="InterPro:IPR003660" /db_xref="InterPro:IPR005467" /db_xref="InterPro:IPR011712" /db_xref="InterPro:IPR017202" /db_xref="InterPro:IPR036890" /db_xref="SubtiList:BG14134" /db_xref="UniProtKB/Swiss-Prot:O32198" /translation="MRKKMLASLQWRAIRMTTGISLLLFVCLISFMMFYYRLDPLVLL SSSWFGIPFILILLLISVTVGFASGYMYGNRLKTRIDTLIESILTFENGNFAYRIPPL GDDEIGLAADQLNEMAKRVELQVASLQKLSNERAEWQAQMKKSVISEERQRLARDLHD AVSQQLFAISMMTSAVLEHVKDADDKTVKRIRMVEHMAGEAQNEMRALLLHLRPVTLE GKGLKEGLTELLDEFRKKQPIDIEWDIQDTAISKGVEDHLFRIVQEALSNVFRHSKAS KVTVILGIKNSQLRLKVIDNGKGFKMDQVKASSYGLNSMKERASEIGGVAEVISVEGK GTQIEVKVPIFPEEKGENERDSSIID*" gene complement(3260633..3261715) /gene="liaS" /locus_tag="BSU_33090" /old_locus_tag="BSU33090" CDS complement(3261712..3262437) /gene="liaF" /locus_tag="BSU_33100" /old_locus_tag="BSU33100" /function="16.6: Maintain" /function="16.3: Control" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:15273097, 15849754, 16816187, 16850406, 17660417, 17921301, 23279150, 23326432" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15273097, 15849754, 16816187, 16850406, 17660417, 17921301, 23279150, 23326432; Product type rc: receptor" /codon_start=1 /transl_table=11 /product="membrane component associated to the LiaRS two-component system" /protein_id="NP_391190.1" /db_xref="EnsemblGenomes-Gn:BSU33100" /db_xref="EnsemblGenomes-Tr:CAB15300" /db_xref="GOA:O32199" /db_xref="InterPro:IPR016975" /db_xref="InterPro:IPR024425" /db_xref="SubtiList:BG14135" /db_xref="UniProtKB/Swiss-Prot:O32199" /translation="MTKKQLLGLIIALFGISMFLQIIGIGDLLFWPLFFLIAGYFLKK YSRDWLGSVMYIFAAFLFLKNLFSITFNLFGYAFAAFLIYAGYRLIKGKPIFEPNEKQ VNLNKKEHHEPPKDVKHPDMRSFFIGELQMMKQPFDLNDLNVSGFIGDIKIDLSKAMI PEGESTIVISGVIGNVDIYVPSDLEVAVSSAVFIGDINLIGSKKSGLSTKVYAASTDF SESKRRVKVSVSLFIGDVDVKYV*" gene complement(3261712..3262437) /gene="liaF" /locus_tag="BSU_33100" /old_locus_tag="BSU33100" CDS complement(3262471..3263343) /gene="liaG" /locus_tag="BSU_33110" /old_locus_tag="BSU33110" /function="16.8: Protect" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:15273097, 16816187, 23326432" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15273097, 16816187, 23326432; Product type rc: receptor" /codon_start=1 /transl_table=11 /product="sensor of antibiotic stress on the cell wall" /protein_id="NP_391191.2" /db_xref="EnsemblGenomes-Gn:BSU33110" /db_xref="EnsemblGenomes-Tr:CAB15301" /db_xref="InterPro:IPR025164" /db_xref="SubtiList:BG14136" /db_xref="UniProtKB/Swiss-Prot:O32200" /translation="MKKMLGKLLITAGILVFFAVVVKDVFAAGLGFINGTEADSASAS PRDIDSMVIESDSKDVRIIAEERSDISAGISGDSGKLFVTENKRKLELTVKEKEFQFL NGFNRSTLIVRLPYDYKGDLAVRTSSGDVSVAGNDHLALSGLNAVSASGNTSVTDVRI QDLKVKASSGDVSISNTVSKTAGIDLASGDANLVHVSGSLDVKMTSGDFNAVLKKVTG PVSVTLTSGDANVSLPQNGSFAVNALSASGDVSSPYSFADKGHKEQHHITGTQGSGRH PIDIKTDSGDLAIR*" gene complement(3262471..3263343) /gene="liaG" /locus_tag="BSU_33110" /old_locus_tag="BSU33110" promotor_-10 complement(3263362..3263381) /Source="Nicolas_upshift_promotors" /id="U2596" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.992007992007992" /psig="0.999000999001" /xcortree=2136 /SigmaFactorBS="cggaacggggaaggatttgcggtcaagtccttcccttccgca cGTATcaattcgcaagcttTTCCTTTATAATAGAATGAAtgagaaggatgaaaccgaa t" /listShort="liaG, liaF, liaS, liaR, S1275" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3263382) /Source="Nicolas_upshifts" /id="U2596" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.992007992007992" /psig="0.999000999001" /xcortree=2136 /SigmaFactorBS="cggaacggggaaggatttgcggtcaagtccttcccttccgca cGTATcaattcgcaagcttTTCCTTTATAATAGAATGAAtgagaaggatgaaaccgaa t" /listShort="liaG, liaF, liaS, liaR, S1275" /GFF_Attribute="listLong" promotor_-35 complement(3263396..3263399) /Source="Nicolas_upshift_promotors" /id="U2596" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.992007992007992" /psig="0.999000999001" /xcortree=2136 /SigmaFactorBS="cggaacggggaaggatttgcggtcaagtccttcccttccgca cGTATcaattcgcaagcttTTCCTTTATAATAGAATGAAtgagaaggatgaaaccgaa t" /listShort="liaG, liaF, liaS, liaR, S1275" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3263444..3264121) /gene="liaH" /locus_tag="BSU_33120" /old_locus_tag="BSU33120" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:15273097, 16816187, 23874669, 24666271, 28546427" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15273097, 16816187, 23874669, 24666271, 28546427; Product type f: factor" /codon_start=1 /transl_table=11 /product="modulator of liaIHGFSR (yvqIHGFEC) operon expression" /protein_id="NP_391192.1" /db_xref="EnsemblGenomes-Gn:BSU33120" /db_xref="EnsemblGenomes-Tr:CAB15302" /db_xref="GOA:O32201" /db_xref="InterPro:IPR007157" /db_xref="SubtiList:BG14137" /db_xref="UniProtKB/Swiss-Prot:O32201" /translation="MVLKRIRDMFVASVHEGLDKMENPKVMLNQYVRDMESDIAKAKQ TIVKQHTIAYQFKKKYEEAAEVAGKRKNQAQLAFDAGEEELAKKALTEMKYLEGKAAE HKASYEQANSQLADLKEQLAALETKLQDVKDKKQALIARANAAKAKEHMNTTFDKIDS ESAYREFLRIENRIEEMEIRANYSKSAEAGTELTRKEFADDVEAEIEKMRTLSLQKSD QTKAANE*" gene complement(3263444..3264121) /gene="liaH" /locus_tag="BSU_33120" /old_locus_tag="BSU33120" downshifts complement(3263460) /Source="Nicolas_upshifts" /id="D1710" /incds=0 /nref=2 /ntot=28 /MaxReadThrough="3.84852" /MaxDrop="3.1352" /score="-8.3477012" /energy="-4.5" /TU="U2597" /idTUdmin="U2598" /TUdmin=1243 /isTUend="FALSE" CDS complement(3264148..3264528) /gene="liaI" /locus_tag="BSU_33130" /old_locus_tag="BSU33130" /function="16.1: Circulate" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:15273097, 15849754, 16816187, 16850406, 22720735, 24666271, 28546427" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15273097, 15849754, 16816187, 16850406, 22720735, 24666271, 28546427; Product type s: structure" /codon_start=1 /transl_table=11 /product="membrane anchor for the phage-shock protein A homolog LiaH" /protein_id="NP_391193.1" /db_xref="EnsemblGenomes-Gn:BSU33130" /db_xref="EnsemblGenomes-Tr:CAB15303" /db_xref="GOA:O32202" /db_xref="SubtiList:BG14138" /db_xref="UniProtKB/Swiss-Prot:O32202" /translation="MKINKKTIGGFLLIVFGISVFFGGGSFGFIIPLAIGSLMTYAGI KRFAAGKTITGIIVGGIGAIMLICSLPFVVGIALAAAMVYYGWKLMKNGSADNGVSSF DPEPASAAYQSHFDDEWEEFLKKK*" gene complement(3264148..3264528) /gene="liaI" /locus_tag="BSU_33130" /old_locus_tag="BSU33130" promotor_-10 complement(3264551..3264570) /Source="Nicolas_upshift_promotors" /id="U2597" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.672327672327672" /psig="0.91008991008991" /xcortree=648 /SigmaFactorBS="cgagatacgactccggtcttatataaaaatcaatctctgatt cGTTTtgcatatcttccaaCTTGTATAAGATGAAGACAAggaaaacgaaaggaggatc t" /listShort="liaI, liaH, liaG, liaF, liaS, liaR" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3264571) /Source="Nicolas_upshifts" /id="U2597" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.672327672327672" /psig="0.91008991008991" /xcortree=648 /SigmaFactorBS="cgagatacgactccggtcttatataaaaatcaatctctgatt cGTTTtgcatatcttccaaCTTGTATAAGATGAAGACAAggaaaacgaaaggaggatc t" /listShort="liaI, liaH, liaG, liaF, liaS, liaR" /GFF_Attribute="listLong" promotor_-35 complement(3264585..3264588) /Source="Nicolas_upshift_promotors" /id="U2597" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.672327672327672" /psig="0.91008991008991" /xcortree=648 /SigmaFactorBS="cgagatacgactccggtcttatataaaaatcaatctctgatt cGTTTtgcatatcttccaaCTTGTATAAGATGAAGACAAggaaaacgaaaggaggatc t" /listShort="liaI, liaH, liaG, liaF, liaS, liaR" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3264690..3265958) /gene="yvqJ" /locus_tag="BSU_33140" /old_locus_tag="BSU33140" /function="16.1: Circulate" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15273097, 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative efflux protein" /protein_id="NP_391194.1" /db_xref="EnsemblGenomes-Gn:BSU33140" /db_xref="EnsemblGenomes-Tr:CAB15304" /db_xref="GOA:O32203" /db_xref="InterPro:IPR011701" /db_xref="InterPro:IPR020846" /db_xref="InterPro:IPR036259" /db_xref="SubtiList:BG14139" /db_xref="UniProtKB/Swiss-Prot:O32203" /translation="MVNLIESDSIWKRNFNYLFFSRIVKISGDMFAFNSILWFLIYDG KGAIGTALLIAVTFLPEAVLAPVTGPFMKQTTLKFWMYFSDLTRAAIVLIIPLCHFAG FSPLWFVMTLMIVHSATGAAYNPASIALIPQIVNEQGIQKANAVLQSSAQIVRLGAVT LCGAFLTFISPSYTMLIALVLYLVSGFLVLFIKYTAVESQSESAVVTQRGTYIGRLKR GFRLVRKHQILYPLAIYCIFMNFAAAPWEALSAVYVAEDLNGQPIVYSLLKATTAAGA FLLGFVLAKVKVNRYGLLFVTAGIIEGFAFFITGMNTFLPLVFFAAFTFGAAVSAVNV PEYTIIQTSVDSEDQPQVYAVIHMISNISIPAGAVICGYAANAFGSGKVIAVGGIVEI IAGIGILLFTKLAKAERSDLIKEREASVHL*" gene complement(3264690..3265958) /gene="yvqJ" /locus_tag="BSU_33140" /old_locus_tag="BSU33140" downshifts complement(3264703) /Source="Nicolas_upshifts" /id="D1711" /incds=0 /nref=78 /ntot=164 /MaxReadThrough="0.70612" /MaxDrop="4.80625" /score="32.7496145" /energy="-12.9" /TU="NA" /idTUdmin="U2598" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(3265992..3266011) /Source="Nicolas_upshift_promotors" /id="U2598" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.994005994005994" /psig=1 /xcortree=482 /SigmaFactorBS="attttacgacaaaaaatgaaccttatgaatTATTGACTgaaa aatggaaaaaTGAGATATTGTAATAAATAGatgtaaaaaataggcaacggggggctct g" /listShort="yvqJ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3266003) /Source="Nicolas_upshifts" /id="U2598" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.994005994005994" /psig=1 /xcortree=482 /SigmaFactorBS="attttacgacaaaaaatgaaccttatgaatTATTGACTgaaa aatggaaaaaTGAGATATTGTAATAAATAGatgtaaaaaataggcaacggggggctct g" /listShort="yvqJ" /GFF_Attribute="listLong" promotor_-35 complement(3266026..3266033) /Source="Nicolas_upshift_promotors" /id="U2598" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.994005994005994" /psig=1 /xcortree=482 /SigmaFactorBS="attttacgacaaaaaatgaaccttatgaatTATTGACTgaaa aatggaaaaaTGAGATATTGTAATAAATAGatgtaaaaaataggcaacggggggctct g" /listShort="yvqJ" /GFF_Attribute="listLong" /label="promotor_-35" downshifts complement(3266129) /Source="Nicolas_upshifts" /id="D1712" /incds=0 /nref=33 /ntot=211 /MaxReadThrough="1.54601" /MaxDrop="4.92923" /score="51.1311697" /energy="-17.1" /TU="NA" /idTUdmin="U2599" /TUdmin=4 /isTUend="TRUE" CDS complement(3266135..3266716) /gene="yvqK" /locus_tag="BSU_33150" /old_locus_tag="BSU33150" /EC_number="2.5.1.17" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 12869542, 14704351, 17588214, 19933577, 21514283; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative ATP:cob(I)alamin adenosyltransferase" /protein_id="NP_391195.2" /db_xref="EnsemblGenomes-Gn:BSU33150" /db_xref="EnsemblGenomes-Tr:CAB15305" /db_xref="GOA:O34899" /db_xref="InterPro:IPR016030" /db_xref="InterPro:IPR029499" /db_xref="InterPro:IPR036451" /db_xref="PDB:1RTY" /db_xref="SubtiList:BG14140" /db_xref="UniProtKB/Swiss-Prot:O34899" /translation="MKLYTKTGDKGQTGLVGGRTDKDSLRVESYGTIDELNSFIGLAL AELSGQPGFEDLTAELLTIQHELFDCGGDLAIVTERKDYKLTEESVSFLETRIDAYTA EAPELKKFILPGGSKCASLLHIARTITRRAERRVVALMKSEEIHETVLRYLNRLSDYF FAAARVVNARSGIGDVEYERSAIVFRDRNSSES*" gene complement(3266135..3266716) /gene="yvqK" /locus_tag="BSU_33150" /old_locus_tag="BSU33150" CDS complement(3266739..3268067) /gene="yvrA" /locus_tag="BSU_33160" /old_locus_tag="BSU33160" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 14704351; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative vitamin B12 transport system, ATPase component" /protein_id="NP_391196.1" /db_xref="EnsemblGenomes-Gn:BSU33160" /db_xref="EnsemblGenomes-Tr:CAB15306" /db_xref="GOA:O34631" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG14141" /db_xref="UniProtKB/Swiss-Prot:O34631" /translation="MKAEGLSGGYGDSRLINNVSLTVEKGEFLGILGPNGSGKTTLLH LLTGTLPAKKGRVYLAGKLLADYKPKELAQIMAVLPQKMDQAFTFTVEETVAFGRYPF QTGLFRQQTEKGEAIVQEAMEQTGVADFAQKPIRELSGGEQQRVYLAQALAQQPRILF LDEPTNFLDLAYQKDLLDLIKRLTRESGLAAVSVFHDLNTASLYCDGLMFMKNGTAGP KQKPEYAVTEQSIKAVYDTDVTALVHQSSPKPMIVIQPEKDSVKRQSIPFEALLQAGR DDILLQTEIPLRTLSSTPIGAGFSWSRTLIHKRLPDQPDPIEGLTACLSESGFQLQET CAMASSERLDRFVYRTYEDGELSVFICVQTGFSIWILINGYAADQFFIKALMAAEAER TKVLGDGGGTGDILIAATQTQQSENIEQRLNQLIKKGTAECIKEAAELFE*" gene complement(3266739..3268067) /gene="yvrA" /locus_tag="BSU_33160" /old_locus_tag="BSU33160" CDS complement(3268067..3269128) /gene="yvrB" /locus_tag="BSU_33170" /old_locus_tag="BSU33170" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 14704351, 15849754, 16850406, 25917914; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative vitamin B12 permease" /protein_id="NP_391197.1" /db_xref="EnsemblGenomes-Gn:BSU33170" /db_xref="EnsemblGenomes-Tr:CAB15307" /db_xref="GOA:O34451" /db_xref="InterPro:IPR000522" /db_xref="InterPro:IPR035568" /db_xref="SubtiList:BG14142" /db_xref="UniProtKB/Swiss-Prot:O34451" /translation="MRKAFTRIRLRNNRYAAYIIGFSFLAVSIILGISCGSLHIPIPA VFRVFWHQGFGGSIGSDDPMYTNIMMNIRLPRVVLAALVGAALSIAGAAFQGLLKNPL ADPYTLGVSSGASVGAVVTLFLGLHLPVIGGFTLPVLSVAAALATMAAVLFFSRLVHA SMSVSTLILTGVITNSFLGAFISLIIALTGDNLLPIVHWLLGSVSMRGWSYVILFLPF FLLGTILLIINGRELNVMTYGEDKAKLLGVSVQQRKMMILIAGSLLTGSAVAVSGTIG FVGLVIPHITRLLWGTDHRHLLPLSALLGAGFLVLADLLSRTIIEPIELPIGIITSLA GAPVFALILIRQHRGGRSL*" gene complement(3268067..3269128) /gene="yvrB" /locus_tag="BSU_33170" /old_locus_tag="BSU33170" CDS complement(3269091..3270035) /gene="yvrC" /locus_tag="BSU_33180" /old_locus_tag="BSU33180" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 14704351, 25917914; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative lipoprotein binding vitamin B12" /protein_id="NP_391198.1" /db_xref="EnsemblGenomes-Gn:BSU33180" /db_xref="EnsemblGenomes-Tr:CAB15308" /db_xref="GOA:O34805" /db_xref="InterPro:IPR002491" /db_xref="SubtiList:BG14143" /db_xref="UniProtKB/Swiss-Prot:O34805" /translation="MKKRAGIWAALLLAAVMLAGCGNPADQKDSKAKQKTEVFPVTID DASNQDVTIKKEPKKIVSLMPSNTEITYALGLGDKVVGVTTNDTYPKEVKKVEKVGDM NVNVEKVISLKPDLVLAHESSMSASADAIKQLKDAGITVLTVNDAQSFSEVYKSIEMI GEAGGAEKKADQLVKSMKSDLKDIQEKAKTISKDEEKSVFIEVSPDPDIYTTGKDTFM NEMLNVIHAKNAAADQTGWVQMTDEAIVKLNPDAIVTTDGVKAKAVEKRDGWSEINAV KHHRVYDVDPDLVTRSGPRLIEGVEELAESIYPDTFKE*" gene complement(3269091..3270035) /gene="yvrC" /locus_tag="BSU_33180" /old_locus_tag="BSU33180" S_feature complement(3270036..3270305) /Source="Nicolas_S_feature" /locus_tag="new_3404438_3404707_c" /HighExp="LBGtran, LBGexp, Etha, LPh, S3, Lbexp, G180, dia0, HPh, Mt0" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigB" /TUshortPSig="0.956, 1" /TUlongSig="SigA" /TUlongPSig="0.925" /label="S1276" misc_RNA complement(3270144..3270274) /gene="srbL" /locus_tag="BSU_misc_RNA_85" /product="putative coenzyme B12 (AdoCbl) riboswitch" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 14704351, 17038623, 21140903, 25917914; Product type n: RNA" /function="16.3: Control" gene complement(3270144..3270274) /gene="srbL" /locus_tag="BSU_misc_RNA_85" promotor_-10 complement(3270282..3270301) /Source="Nicolas_upshift_promotors" /id="U2599" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.899100899100899" /psig="0.956043956043956" /xcortree=2215 /SigmaFactorBS="tttgcttccatacacaatatggggaaaagtcattcaggacaC ATATACAagcctgtcagtcataTAGTATAATTACTCCGAAAAacggatacgaatgtca a" /listShort="S1276, yvrC, yvrB, yvrA, yvqK" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3270305) /Source="Nicolas_upshifts" /id="U2599" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.899100899100899" /psig="0.956043956043956" /xcortree=2215 /SigmaFactorBS="tttgcttccatacacaatatggggaaaagtcattcaggacaC ATATACAagcctgtcagtcataTAGTATAATTACTCCGAAAAacggatacgaatgtca a" /listShort="S1276, yvrC, yvrB, yvrA, yvqK" /GFF_Attribute="listLong" S_feature complement(3270307..3271234) /Source="Nicolas_S_feature" /locus_tag="new_3404709_3405636_c" /HighExp="Etha, B60, Sw, M9-stat, B36, C30, C90, Salt, G135, Gly" /AntisenseName="yvrD" /AntisenseCor="1.5286196477289399E-2" /AntisenseRegPval="-0.1" /CDS_PredictionProba="NA" /TUshortSig="SigB" /TUshortPSig=1 /TUlongSig="SigA" /TUlongPSig="0.925" /label="S1277" promotor_-35 complement(3270317..3270324) /Source="Nicolas_upshift_promotors" /id="U2599" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.899100899100899" /psig="0.956043956043956" /xcortree=2215 /SigmaFactorBS="tttgcttccatacacaatatggggaaaagtcattcaggacaC ATATACAagcctgtcagtcataTAGTATAATTACTCCGAAAAacggatacgaatgtca a" /listShort="S1276, yvrC, yvrB, yvrA, yvqK" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 3270367..3270374 /Source="Nicolas_upshift_promotors" /id="U2600" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.868131868131868" /psig="0.992007992007992" /xcortree=1946 /SigmaFactorBS="atgacttttccccatattgtgtatggaagcaaaaTCCTCGTA aacactaaatttgaTCTTGTATACTTAATACCATcatctatcaaaaggaatgattctt a" /listShort="yvrD" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3270389..3270408 /Source="Nicolas_upshift_promotors" /id="U2600" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.868131868131868" /psig="0.992007992007992" /xcortree=1946 /SigmaFactorBS="atgacttttccccatattgtgtatggaagcaaaaTCCTCGTA aacactaaatttgaTCTTGTATACTTAATACCATcatctatcaaaaggaatgattctt a" /listShort="yvrD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3270393 /Source="Nicolas_upshifts" /id="U2600" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.868131868131868" /psig="0.992007992007992" /xcortree=1946 /SigmaFactorBS="atgacttttccccatattgtgtatggaagcaaaaTCCTCGTA aacactaaatttgaTCTTGTATACTTAATACCATcatctatcaaaaggaatgattctt a" /listShort="yvrD" /GFF_Attribute="listLong" CDS 3270433..3271224 /gene="yvrD" /locus_tag="BSU_33190" /old_locus_tag="BSU33190" /EC_number="1.-.-.-" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 9922248; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative oxidoreductase" /protein_id="NP_391199.1" /db_xref="EnsemblGenomes-Gn:BSU33190" /db_xref="EnsemblGenomes-Tr:CAB15309" /db_xref="GOA:O34782" /db_xref="InterPro:IPR002347" /db_xref="InterPro:IPR020904" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG14144" /db_xref="UniProtKB/Swiss-Prot:O34782" /translation="MDLQLKEKLVLITGSTSGIGKAAAKSFLQEGAAVIVNGRKQETV DRTIEELSGYGTVHGAAADLSKTDEAAAFIEKVNEIGDIDILVNNLGFFEVKDFADVT DEEWNQYFEVNVMSAVRTSRHFLPKMLAKNSGRILNIASEAGVKPLPTMIPYSMTKTA LISLSRGMAEMTKGTNVTVNSVLPGPTWTEGVASYMEGAAQAAGQDTDTFIKDYFKVN EPTSLIQRYATAEEVANTIVFLASDAASAINGTAQRVEGGIIRSL*" gene 3270433..3271224 /gene="yvrD" /locus_tag="BSU_33190" /old_locus_tag="BSU33190" downshifts 3271095 /Source="Nicolas_upshifts" /id="D1713" /incds=1 /nref=2 /ntot=89 /MaxReadThrough="6.202" /MaxDrop="3.35017" /score="36.8938178" /energy="-12" /TU="U2600" /idTUdmin="U2600" /TUdmin="-110" /isTUend="FALSE" downshifts 3271205 /Source="Nicolas_upshifts" /id="D1714" /incds=0 /nref=105 /ntot=218 /MaxReadThrough="2.44739" /MaxDrop="6.33457" /score="36.8938178" /energy="-12" /TU="NA" /idTUdmin="U2600" /TUdmin=0 /isTUend="TRUE" CDS complement(3271262..3272140) /gene="yvrE" /locus_tag="BSU_33200" /old_locus_tag="BSU33200" /EC_number="3.1.1.-" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative sugar lactone lactonase" /protein_id="NP_391200.1" /db_xref="EnsemblGenomes-Gn:BSU33200" /db_xref="EnsemblGenomes-Tr:CAB15310" /db_xref="GOA:O34940" /db_xref="InterPro:IPR005511" /db_xref="InterPro:IPR011042" /db_xref="InterPro:IPR013658" /db_xref="SubtiList:BG14145" /db_xref="UniProtKB/Swiss-Prot:O34940" /translation="MDAVLEADTRAVIGEGPLWDEENGRLYWVDILGSELHIFDPEEK INRSIKFKSFVTALAKYSKDELIMTMKDGFYLYHLRDDSLEKIKQPKDMHESLRFNDA KCDPYGRLWAGTTSMEGEQKQASLYRLNLDGSLVKIKDQVSTSNGLDWDRERNLMYYI DTPTQEIVRYSYDPQSGDVSNPEPVYRFDQSDGLPDGMTIDQNGMLWVALFGGSRVVH IDPFQKKEINSISVPAKYVTCCAFGGRDLKTLYITTATEQMTEKERYEQPHAGGLFSA QLETGGYQPVPFAGDV*" gene complement(3271262..3272140) /gene="yvrE" /locus_tag="BSU_33200" /old_locus_tag="BSU33200" downshifts complement(3271279) /Source="Nicolas_upshifts" /id="D1715" /incds=0 /nref=31 /ntot=260 /MaxReadThrough="7.17016" /MaxDrop="5.74101" /score="29.8014794" /energy="-12" /TU="U2601" /idTUdmin="U2602" /TUdmin="-20" /isTUend="TRUE" promotor_-10 complement(3272164..3272182) /Source="Nicolas_upshift_promotors" /id="U2601" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=160 /SigmaFactorBS="cggtcattaccatcctttttaaaaaacaataaacatcaagtG GTTTGGacacctctttgccGGGAATAACAATATATAGActgaagctaaagaggtgtaa c" /listShort="yvrE, S1277, S1276, yvrC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3272183) /Source="Nicolas_upshifts" /id="U2601" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=160 /SigmaFactorBS="cggtcattaccatcctttttaaaaaacaataaacatcaagtG GTTTGGacacctctttgccGGGAATAACAATATATAGActgaagctaaagaggtgtaa c" /listShort="yvrE, S1277, S1276, yvrC" /GFF_Attribute="listLong" promotor_-35 complement(3272196..3272202) /Source="Nicolas_upshift_promotors" /id="U2601" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=160 /SigmaFactorBS="cggtcattaccatcctttttaaaaaacaataaacatcaagtG GTTTGGacacctctttgccGGGAATAACAATATATAGActgaagctaaagaggtgtaa c" /listShort="yvrE, S1277, S1276, yvrC" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3272212..3273954) /gene="yvrG" /locus_tag="BSU_33210" /old_locus_tag="BSU33210" /function="16.12: Sense" /experiment="publication(s) with functional evidences, PMID:11717295, 16306698, 25879813" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11717295, 16306698, 25879813; Product type rc: receptor" /codon_start=1 /transl_table=11 /product="two-component sensor histidine kinase YvrG [cellwall processes and sublancin production and immunity(YvrH)]" /protein_id="NP_391201.2" /db_xref="EnsemblGenomes-Gn:BSU33210" /db_xref="EnsemblGenomes-Tr:CAB15311" /db_xref="GOA:O34989" /db_xref="InterPro:IPR003594" /db_xref="InterPro:IPR003661" /db_xref="InterPro:IPR004358" /db_xref="InterPro:IPR005467" /db_xref="InterPro:IPR036097" /db_xref="InterPro:IPR036890" /db_xref="SubtiList:BG14146" /db_xref="UniProtKB/Swiss-Prot:O34989" /translation="MRLRWKFLFHFFGQMLIVILLLTVMLVASFFYLDARFSDAESNS GLTKATTDTLEAYLDVNEDGTWEVDNFLKKSVDKQHGWMQIIDSEGNTDYSYGVPKDV PGTYTKKELLSIYKTKKLHNYKLNYWAINIEDKSYLLLSGWKSKSEQLLTSVEKREQK IDSLAHYKSSTIDYIKRKKGAIYLLDSNGKILDSINSTKSERKTMNQLELLKYSSKPW NYKREISVKILNKDRWMVATVPNPVYVTDQEFNKSFLKVVLKAMFLVMAVLFMYIIWM TVWYMFRFGLPIFHTIRWLVNLSKGKLEEPRNREGRPVSKNKKGKIKQPYRFFGEIFE SMDQLTETLRRDKRNREKIQATREEWIAGLSHDLKTPLSSIYGYSMMLESKQYDWSPE EVKEMGQVVREKSEYMSKLIEDLNLTYRLKNDALPIERKLTSLIPFFKNVIEDFKKNP FSEGYDISFVSKEEHIEFALDEAWFRRILENLLGNAVKHNGKGTEIQVILEQTKNHIS LKVKDNGKGMDEETITHLFNRYYRGTNTKDSTAGTGLGLAIAKELVHLHNGTIHVNSR TNIGTVITILFKKQ*" gene complement(3272212..3273954) /gene="yvrG" /locus_tag="BSU_33210" /old_locus_tag="BSU33210" CDS complement(3273951..3274664) /gene="yvrH" /locus_tag="BSU_33221" /old_locus_tag="BSU33221" /function="16.8: Protect" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:11717295, 16306698, 25879813" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11717295, 16306698, 25879813; Product type r: regulator" /codon_start=1 /transl_table=11 /product="two-component sensor histidine kinase YvrG [cellwall processes and sublancin production and immunity(YvrG)]" /protein_id="NP_391202.2" /db_xref="EnsemblGenomes-Gn:BSU33221" /db_xref="EnsemblGenomes-Tr:CAB15312" /db_xref="GOA:P94504" /db_xref="InterPro:IPR001789" /db_xref="InterPro:IPR001867" /db_xref="InterPro:IPR011006" /db_xref="InterPro:IPR016032" /db_xref="InterPro:IPR036388" /db_xref="SubtiList:BG12452" /db_xref="UniProtKB/Swiss-Prot:P94504" /translation="MENASILIVDDEKAIVDMIKRVLEKEGYRNILDAASAEEAIPVV KANKVDLIVLDVMMGGMSGFEACTLIREYSDAPIFFLTARSSDADKLSGFAVGADDYI TKPFNPLELAARIRAHLKRTYQSKETSSNQTYTYDYFTFSPQNAELIVGGEAVACSAQ LLQLLQYFCEHPNVVLSKDQIYEKVWGYPSYGDNNTVMVHIRKLREKIERDPSNPEYI VTVRGLGYRFIPNPEGKRS*" gene complement(3273951..3274664) /gene="yvrH" /locus_tag="BSU_33221" /old_locus_tag="BSU33221" misc_feature complement(3274695..3274714) /Source="Nicolas_upshift_promotors" /id="U2602" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.629370629370629" /psig="0.925074925074925" /xcortree=2348 /SigmaFactorBS="ccttttttgctgttttgatttgccaaggctccaatgtattca aaaatgtaccataaataAACGATATAATGATAAGATGaaaaaaacagtgacagaaagg a" /listShort="yvrH, yvrG, yvrE" /listLong="S1277, S1276, yvrC" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(3274713) /Source="Nicolas_upshifts" /id="U2602" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.629370629370629" /psig="0.925074925074925" /xcortree=2348 /SigmaFactorBS="ccttttttgctgttttgatttgccaaggctccaatgtattca aaaatgtaccataaataAACGATATAATGATAAGATGaaaaaaacagtgacagaaagg a" /listShort="yvrH, yvrG, yvrE" /listLong="S1277, S1276, yvrC" CDS complement(3274817..3275056) /gene="rsoA" /locus_tag="BSU_33222" /old_locus_tag="BSU33222" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:18573182, 19047353, 27558998" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 18573182, 19047353, 27558998; Product type r: regulator" /codon_start=1 /transl_table=11 /product="regulator of sigma-O" /protein_id="YP_003097787.1" /db_xref="EnsemblGenomes-Gn:BSU33222" /db_xref="EnsemblGenomes-Tr:CAX52693" /db_xref="GOA:C0H3R4" /db_xref="UniProtKB/Swiss-Prot:C0H3R4" /translation="MDGQFEQKKKQKDETYDIEHLIACFSPMIRKKLSNTSYQEREDL EQELKIKMFEKADMLLCQDVPGFWEFILYMVDENS*" gene complement(3274817..3275056) /gene="rsoA" /locus_tag="BSU_33222" /old_locus_tag="BSU33222" downshifts complement(3274824) /Source="Nicolas_upshifts" /id="D1716" /incds=0 /nref=4 /ntot=30 /MaxReadThrough="2.45068" /MaxDrop="3.82244" /score="12.6471586" /energy="-8.2" /TU="NA" /idTUdmin="U2605" /TUdmin="-5" /isTUend="TRUE" promotor_-10 complement(3275052..3275070) /Source="Nicolas_upshift_promotors" /id="U2603" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.957042957042957" /psig="0.957042957042957" /xcortree=142 /SigmaFactorBS="ataaaaaggggctggagaatatcagaaagcAGTTAGCggcgc aaaaaaaggGGGAAAAGTAAGCTGTGGAcggccagtttgaacaaaaaaagaaacaaaa a" /listShort="rsoA" /GFF_Attribute="listLong" /label="promotor_-10" CDS complement(3275060..3275590) /gene="sigO" /locus_tag="BSU_33230" /old_locus_tag="BSU33230" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:16306698, 18573182, 19047353, 27558998" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16306698, 18573182, 19047353, 27558998; Product type r: regulator" /codon_start=1 /transl_table=11 /product="alternative sigma factor" /protein_id="NP_391203.2" /db_xref="EnsemblGenomes-Gn:BSU33230" /db_xref="EnsemblGenomes-Tr:CAB15313" /db_xref="GOA:O34843" /db_xref="InterPro:IPR007630" /db_xref="InterPro:IPR013324" /db_xref="InterPro:IPR014284" /db_xref="InterPro:IPR036388" /db_xref="SubtiList:BG14147" /db_xref="UniProtKB/Swiss-Prot:O34843" /translation="MKHPIVKHFLSNPQHYRLFKNVMESPNEKDARSLDELFKQFYKE IRIVKYMNSMIRIFSIDFDKRVRKNQKRYPLTVDHPEAGDRLSSETGSDAFEEFLDRQ DDLSQHVQDYQLYQAIQKLTDKQKSVLTKVYLHGATMQEIADSLGESRQNISNIHKKG LENIRKQLAAQKKGEK*" gene complement(3275060..3275590) /gene="sigO" /locus_tag="BSU_33230" /old_locus_tag="BSU33230" upshifts complement(3275061) /Source="Nicolas_upshifts" /id="U2603" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.957042957042957" /psig="0.957042957042957" /xcortree=142 /SigmaFactorBS="ataaaaaggggctggagaatatcagaaagcAGTTAGCggcgc aaaaaaaggGGGAAAAGTAAGCTGTGGAcggccagtttgaacaaaaaaagaaacaaaa a" /listShort="rsoA" /GFF_Attribute="listLong" promotor_-35 complement(3275085..3275091) /Source="Nicolas_upshift_promotors" /id="U2603" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.957042957042957" /psig="0.957042957042957" /xcortree=142 /SigmaFactorBS="ataaaaaggggctggagaatatcagaaagcAGTTAGCggcgc aaaaaaaggGGGAAAAGTAAGCTGTGGAcggccagtttgaacaaaaaaagaaacaaaa a" /listShort="rsoA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(3275593..3275612) /Source="Nicolas_upshift_promotors" /id="U2604" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.974025974025974" /psig=1 /xcortree=2005 /SigmaFactorBS="tcatttaatttagtagggaggcggttTGATGGACtatcaaag tcttttACGGTCAAAATGTAAGGAGAtaatgaagcatcccatcgtgaagcattttttg a" /listShort="sigO, rsoA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3275600) /Source="Nicolas_upshifts" /id="U2604" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.974025974025974" /psig=1 /xcortree=2005 /SigmaFactorBS="tcatttaatttagtagggaggcggttTGATGGACtatcaaag tcttttACGGTCAAAATGTAAGGAGAtaatgaagcatcccatcgtgaagcattttttg a" /listShort="sigO, rsoA" /GFF_Attribute="listLong" CDS 3275605..3275943 /gene="yvrJ" /locus_tag="BSU_33239" /old_locus_tag="BSU33239" /experiment="publication(s) with functional evidences, PMID:18573182, 19047353" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 18573182, 19047353; Product type f: factor" /codon_start=1 /transl_table=11 /product="factor involved in oxalate decarboxylase expression" /protein_id="YP_003097788.1" /db_xref="EnsemblGenomes-Gn:BSU33239" /db_xref="EnsemblGenomes-Tr:CAX52694" /db_xref="InterPro:IPR024419" /db_xref="UniProtKB/Swiss-Prot:C0H3R5" /translation="MTVKDFDSPSNRLPTKLNEGKQKKVNYYFPPSVFQNTLQQFTFY RFSSLTYMTAEKEGRYFPMDQVFIEEVVKQIGNLGFPALIAMYLLTRFEKKFDQLIEL MTELKDHAKK*" gene 3275605..3275943 /gene="yvrJ" /locus_tag="BSU_33239" /old_locus_tag="BSU33239" promotor_-35 complement(3275627..3275634) /Source="Nicolas_upshift_promotors" /id="U2604" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.974025974025974" /psig=1 /xcortree=2005 /SigmaFactorBS="tcatttaatttagtagggaggcggttTGATGGACtatcaaag tcttttACGGTCAAAATGTAAGGAGAtaatgaagcatcccatcgtgaagcattttttg a" /listShort="sigO, rsoA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(3275643..3275662) /Source="Nicolas_upshift_promotors" /id="U2605" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.276723276723277" /psig="0.538461538461538" /xcortree=388 /SigmaFactorBS="agtattttggaagacactaggcggaaagtagtAGTTTACttt tttttgctttcCTTCATTTAATTTAGTAGGGaggcggtttgatggactatcaaagtct t" /listShort="sigO, rsoA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3275655) /Source="Nicolas_upshifts" /id="U2605" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.276723276723277" /psig="0.538461538461538" /xcortree=388 /SigmaFactorBS="agtattttggaagacactaggcggaaagtagtAGTTTACttt tttttgctttcCTTCATTTAATTTAGTAGGGaggcggtttgatggactatcaaagtct t" /listShort="sigO, rsoA" /GFF_Attribute="listLong" promotor_-35 complement(3275677..3275683) /Source="Nicolas_upshift_promotors" /id="U2605" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.276723276723277" /psig="0.538461538461538" /xcortree=388 /SigmaFactorBS="agtattttggaagacactaggcggaaagtagtAGTTTACttt tttttgctttcCTTCATTTAATTTAGTAGGGaggcggtttgatggactatcaaagtct t" /listShort="sigO, rsoA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_no_box 3275689..3275789 /Source="Nicolas_upshift_promotors" /id="U2606" /multdbtbs="-" /comp="M21" /sig="Sig-" /pcomp="0.3996003996004" /psig="0.277722277722278" /xcortree=389 /SigmaFactorBS="tttccgcctagtgtcttccaaaatactttgcagcagtttacg ttttatcggttttcctcacttacatacatgactgcagaaaaagaagggaggtattttc c" /GFF_Attribute="listShort" /listLong="S1278, oxdC, yvrL" /label="promotor_no_box" upshifts 3275749 /Source="Nicolas_upshifts" /id="U2606" /multdbtbs="-" /comp="M21" /sig="Sig-" /pcomp="0.3996003996004" /psig="0.277722277722278" /xcortree=389 /SigmaFactorBS="tttccgcctagtgtcttccaaaatactttgcagcagtttacg ttttatcggttttcctcacttacatacatgactgcagaaaaagaagggaggtattttc c" /GFF_Attribute="listShort" /listLong="S1278, oxdC, yvrL" promotor_no_box 3275917..3276017 /Source="Nicolas_upshift_promotors" /id="U2607" /multdbtbs="-" /comp="M21" /sig="Sig-" /pcomp="0.405594405594406" /psig="0.316683316683317" /xcortree=387 /SigmaFactorBS="gaactgaaagatcatgcaaaaaaataatttttcaatcgaagt tgacttttcactggtttttttcacttaacaaaacagaagggaaaacgaaaggcctttc a" /listShort="S1278, oxdC, yvrL" /GFF_Attribute="listLong" /label="promotor_no_box" S_feature 3275977..3276063 /Source="Nicolas_S_feature" /locus_tag="new_3410379_3410465" /HighExp="T5.0H, T4.0H, T3.30H, Lbstat, T3.0H, nit, T2.0H, T2.30H, LPhT, T1.30H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="Sig-" /TUshortPSig="0.317" /TUlongSig="Sig-" /TUlongPSig="0.278" /label="S1278" upshifts 3275977 /Source="Nicolas_upshifts" /id="U2607" /multdbtbs="-" /comp="M21" /sig="Sig-" /pcomp="0.405594405594406" /psig="0.316683316683317" /xcortree=387 /SigmaFactorBS="gaactgaaagatcatgcaaaaaaataatttttcaatcgaagt tgacttttcactggtttttttcacttaacaaaacagaagggaaaacgaaaggcctttc a" /listShort="S1278, oxdC, yvrL" /GFF_Attribute="listLong" CDS 3276064..3277221 /gene="oxdC" /locus_tag="BSU_33240" /old_locus_tag="BSU33240" /EC_number="4.1.1.2" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:10960116, 14697267, 14871895, 17459326, 18573182, 19047353, 21255608, 21264418, 21782782, 26744902, 27797181" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10960116, 14697267, 14871895, 17459326, 18573182, 19047353, 21255608, 21264418, 21782782, 26744902, 27797181; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="oxalate decarboxylase" /protein_id="NP_391204.1" /db_xref="EnsemblGenomes-Gn:BSU33240" /db_xref="EnsemblGenomes-Tr:CAB15314" /db_xref="GOA:O34714" /db_xref="InterPro:IPR006045" /db_xref="InterPro:IPR011051" /db_xref="InterPro:IPR014710" /db_xref="InterPro:IPR017774" /db_xref="PDB:1J58" /db_xref="PDB:1L3J" /db_xref="PDB:1UW8" /db_xref="PDB:2UY8" /db_xref="PDB:2UY9" /db_xref="PDB:2UYA" /db_xref="PDB:2UYB" /db_xref="PDB:2V09" /db_xref="PDB:3S0M" /db_xref="PDB:4MET" /db_xref="PDB:5HI0" /db_xref="SubtiList:BG14148" /db_xref="UniProtKB/Swiss-Prot:O34714" /translation="MKKQNDIPQPIRGDKGATVKIPRNIERDRQNPDMLVPPETDHGT VSNMKFSFSDTHNRLEKGGYAREVTVRELPISENLASVNMRLKPGAIRELHWHKEAEW AYMIYGSARVTIVDEKGRSFIDDVGEGDLWYFPSGLPHSIQALEEGAEFLLVFDDGSF SENSTFQLTDWLAHTPKEVIAANFGVTKEEISNLPGKEKYIFENQLPGSLKDDIVEGP NGEVPYPFTYRLLEQEPIESEGGKVYIADSTNFKVSKTIASALVTVEPGAMRELHWHP NTHEWQYYISGKARMTVFASDGHARTFNYQAGDVGYVPFAMGHYVENIGDEPLVFLEI FKDDHYADVSLNQWLAMLPETFVQAHLDLGKDFTDVLSKEKHPVVKKKCSK*" gene 3276064..3277221 /gene="oxdC" /locus_tag="BSU_33240" /old_locus_tag="BSU33240" downshifts 3277207 /Source="Nicolas_upshifts" /id="D1717" /incds=0 /nref=11 /ntot=87 /MaxReadThrough="4.83038" /MaxDrop="4.39135" /score="2.61432951" /energy="-9.4" /TU="U2607" /idTUdmin="U2607" /TUdmin="-484" /isTUend="FALSE" CDS 3277282..3277692 /gene="rsiO" /locus_tag="BSU_33250" /old_locus_tag="BSU33250" /experiment="publication(s) with functional evidences, PMID:15849754, 16850406, 18573182, 19047353, 26651345" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15849754, 16850406, 18573182, 19047353, 26651345; Product type f: factor" /codon_start=1 /transl_table=11 /product="acid stress-sensitive anti sigma factor" /protein_id="NP_391205.1" /db_xref="EnsemblGenomes-Gn:BSU33250" /db_xref="EnsemblGenomes-Tr:CAB15315" /db_xref="GOA:O34686" /db_xref="InterPro:IPR025912" /db_xref="SubtiList:BG14149" /db_xref="UniProtKB/Swiss-Prot:O34686" /translation="MKHQNPSKRLLRLSIKYLLAAAAVVLTYFAVIYILFSLAGTSYR SAAHVLLFAVVFLVLGLCFEPFERLMIHSFTFFKTGKRLFILLAGIVQLLFLWMTAHT TDQLISDIWLSTTEEMIVAAVFLILDKCNSALPS*" gene 3277282..3277692 /gene="rsiO" /locus_tag="BSU_33250" /old_locus_tag="BSU33250" downshifts 3277691 /Source="Nicolas_upshifts" /id="D1718" /incds=0 /nref=1 /ntot=22 /MaxReadThrough="0.57216" /MaxDrop="3.72691" /score="-9.50136752" /energy="-7.4" /TU="NA" /idTUdmin="U2607" /TUdmin=0 /isTUend="TRUE" CDS complement(3277726..3278955) /gene="yvrN" /locus_tag="BSU_33260" /old_locus_tag="BSU33260" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative ABC transporter (ATP-binding protein)" /protein_id="NP_391207.3" /db_xref="EnsemblGenomes-Gn:BSU33260" /db_xref="EnsemblGenomes-Tr:CAB15317" /db_xref="GOA:P46324" /db_xref="InterPro:IPR003838" /db_xref="InterPro:IPR025857" /db_xref="SubtiList:BG11368" /db_xref="UniProtKB/Swiss-Prot:P46324" /translation="MLEHIRISFQSIFSHKLRSILTMLGVIIGIAAIIAIVSMLKGQS EQLKQSMIGMGNNAINVVYQPSGGEEESGGPQVSYASAPPVAEETVKAIKSDPMVKGL SLYYLSEGASVFHLTNVSYPQVYGVDDDYFDMFPIRITEGRKLTENDLNSTHQVVMIN EAVRDELFPDGEALHKSIEMNGVPFKVVGVFKEKNQQESMFEGDYANPVLYVPKKVWP LIEGFDAPTQIAVQADSSEHIQEAGVMAADLLNQGLSEAELEKAEYSVMDLQEIAQEV ESFNQSFALLLGGIASISLLVGGIGVMNIMLVSVTERTREIGIKKALGAKRRVILFQF LTEAVVLTSIGGILGVLAGFGIAKLLTVIFPMPFIVSIPAVVGALIFSMAVGIIFGLL PSIKASKLQPVDALRYE*" gene complement(3277726..3278955) /gene="yvrN" /locus_tag="BSU_33260" /old_locus_tag="BSU33260" downshifts complement(3277743) /Source="Nicolas_upshifts" /id="D1719" /incds=0 /nref=10 /ntot=218 /MaxReadThrough="2.36812" /MaxDrop="4.29282" /score="13.74435" /energy="-11.3" /TU="NA" /idTUdmin="U2608" /TUdmin="-20" /isTUend="TRUE" CDS complement(3278948..3279637) /gene="yvrO" /locus_tag="BSU_33270" /old_locus_tag="BSU33270" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 11544226, 22517742; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative ABC transporter (ATP-binding protein)" /protein_id="NP_391208.2" /db_xref="EnsemblGenomes-Gn:BSU33270" /db_xref="EnsemblGenomes-Tr:CAB15318" /db_xref="GOA:O34979" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR017871" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG14151" /db_xref="UniProtKB/Swiss-Prot:O34979" /translation="MLTLNNISKSYKLGKEEVPILKHINLTVQAGEFLAIMGPSGSGK STLMNIIGCLDRPTSGTYTLDQIDILKGKDGALAEIRNESIGFVFQTFHLLPRLTALQ NVELPMIYNKVKKKERRQRAYEALEKVGLKDRVSYKPPKLSGGQKQRVAIARALVNQP RFILADEPTGALDTKSSEQILALFSELHREGKTIIMITHDPDVAKKADRTVFIRDGEL VLDERGDISHA*" gene complement(3278948..3279637) /gene="yvrO" /locus_tag="BSU_33270" /old_locus_tag="BSU33270" CDS complement(3279621..3280814) /gene="yvrP" /locus_tag="BSU_33280" /old_locus_tag="BSU33280" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative ABC transporter membrane fusion component" /protein_id="NP_391209.1" /db_xref="EnsemblGenomes-Gn:BSU33280" /db_xref="EnsemblGenomes-Tr:CAB15319" /db_xref="GOA:O35007" /db_xref="InterPro:IPR032317" /db_xref="SubtiList:BG14152" /db_xref="UniProtKB/Swiss-Prot:O35007" /translation="MSKKKKWLIGGAICAGVLVLAGIGAGGFYFFTHMNQVAVSSEPY AESVAVYMGGDSESGQTFSGKVEPEKQQKVYIDSEKGSIKKTYVKEGDQVKKGDKLFE YEGEDHSDEVEQANLQIEMTNLQINRLQKSITETEKKLKVAGKEEKNQLQDELDQTNF DLKTSQLELKQHQKELAGLTKNKGSNVITSKHDGIVQSVNQDIADGATGDQAAGPYIQ IVSTGKYLVKSQINELLMDTIKKGSKVRVTLKTGGEGEWKGKVTSIGKLPAGAGEGEE SESFADEEMNPQSSNYPFTILLDSHKGLEVGYHVNIEVMSDNADADTIKLPSDMVIQD DGEPYVWKADENHKAVKQPVEIGETDENDMVEIKSGLTPEDYVIYPDPAVKEGKQVTV NADTE*" gene complement(3279621..3280814) /gene="yvrP" /locus_tag="BSU_33280" /old_locus_tag="BSU33280" promotor_-10 complement(3280858..3280877) /Source="Nicolas_upshift_promotors" /id="U2608" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.877122877122877" /psig=1 /xcortree=2297 /SigmaFactorBS="ttttctatttgattccgtcatttcaataaaagGATTGCAAgt ctttttgaattaATAGATAATATTGGTTAGAAtgtttcgaaaatattacatagtttac a" /listShort="yvrP, yvrO, yvrN" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3280871) /Source="Nicolas_upshifts" /id="U2608" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.877122877122877" /psig=1 /xcortree=2297 /SigmaFactorBS="ttttctatttgattccgtcatttcaataaaagGATTGCAAgt ctttttgaattaATAGATAATATTGGTTAGAAtgtttcgaaaatattacatagtttac a" /listShort="yvrP, yvrO, yvrN" /GFF_Attribute="listLong" promotor_-35 complement(3280892..3280899) /Source="Nicolas_upshift_promotors" /id="U2608" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.877122877122877" /psig=1 /xcortree=2297 /SigmaFactorBS="ttttctatttgattccgtcatttcaataaaagGATTGCAAgt ctttttgaattaATAGATAATATTGGTTAGAAtgtttcgaaaatattacatagtttac a" /listShort="yvrP, yvrO, yvrN" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3280985..3281794) /gene="fhuC" /locus_tag="BSU_33290" /old_locus_tag="BSU33290" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 8388528, 8596459, 10913070, 15802251; Product type t: transporter" /codon_start=1 /transl_table=11 /product="ferrichrome ABC transporter (ATP-binding protein)" /protein_id="NP_391210.1" /db_xref="EnsemblGenomes-Gn:BSU33290" /db_xref="EnsemblGenomes-Tr:CAB15335" /db_xref="GOA:P49938" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR017871" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG11390" /db_xref="UniProtKB/Swiss-Prot:P49938" /translation="MNSLSTEQLGIGYGDRVIVEDLNISIPKGKITTLIGPNGCGKST ILKTMSRIMRSHAGAVYLNGKAIHKMSTKDIAKDMAILPQTPEAPSGLTVHELVSYGR FPHQSGFGRLNDEDRRIIKWALEETGMAEYAERPIEALSGGQRQRVWIAMALAQGTEL LLLDEPTTYLDLAHQLEILQLLDRLNKEQGRTILMVIHDLNHAARFSHYMIALKKGTV IKEGTALEVMTPDILKQVFQIDAEIVTDPRTNKPVCLTYDLIKNEKELVTV*" gene complement(3280985..3281794) /gene="fhuC" /locus_tag="BSU_33290" /old_locus_tag="BSU33290" downshifts complement(3281002) /Source="Nicolas_upshifts" /id="D1720" /incds=0 /nref=190 /ntot=245 /MaxReadThrough="1.31294" /MaxDrop="6.48454" /score="40.5986253" /energy="-11" /TU="NA" /idTUdmin="U2610" /TUdmin="-1" /isTUend="TRUE" promotor_-35 3281141..3281150 /Source="Nicolas_upshift_promotors" /id="U2609" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.994005994005994" /psig="0.994005994005994" /xcortree=1247 /SigmaFactorBS="gtgtcatgacctccagagcagttccttccttgatGACCGTGC CTtttttgagcgcgATCATATAATGAGAAAAACGagctgcatggttaagatcatgaat g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3281163..3281182 /Source="Nicolas_upshift_promotors" /id="U2609" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.994005994005994" /psig="0.994005994005994" /xcortree=1247 /SigmaFactorBS="gtgtcatgacctccagagcagttccttccttgatGACCGTGC CTtttttgagcgcgATCATATAATGAGAAAAACGagctgcatggttaagatcatgaat g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3281167 /Source="Nicolas_upshifts" /id="U2609" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.994005994005994" /psig="0.994005994005994" /xcortree=1247 /SigmaFactorBS="gtgtcatgacctccagagcagttccttccttgatGACCGTGC CTtttttgagcgcgATCATATAATGAGAAAAACGagctgcatggttaagatcatgaat g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" CDS complement(3281810..3282820) /gene="fhuG" /locus_tag="BSU_33300" /old_locus_tag="BSU33300" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 8388528, 8596459, 10913070, 15802251, 15849754, 16850406, 24362930; Product type t: transporter" /codon_start=1 /transl_table=11 /product="ferrichrome ABC transporter (permease)" /protein_id="NP_391211.1" /db_xref="EnsemblGenomes-Gn:BSU33300" /db_xref="EnsemblGenomes-Tr:CAB15336" /db_xref="GOA:P49937" /db_xref="InterPro:IPR000522" /db_xref="InterPro:IPR035568" /db_xref="SubtiList:BG11391" /db_xref="UniProtKB/Swiss-Prot:P49937" /translation="MKTKTNKPLIVMAVTFLLIVVVFFISLNLGVIKIAPLKTLQVFF GQGTARDELVLFEFRLPRIILSLLVGAGISVAGAILQSVSQNELAEPGILGINAGGSL AVVLFIYFFQGSASDLSFFGTFMLPFSALAGAILAAFLIYILAWKKGVTPIRLILVGI GVNAGFNALLLIFQLKMDPHDFMQAAVWISGSIWGANWNMIWAILPWIVILLLFTLYK ARYLNIMQLGDQLATGLGTAVEKERRILLLAAVTLAASCVAAAGGIAFLGLIAPHVAR RLTGPRHQTLIPVSAFIGSFLFLLADTLARNVLAPSEIPVGLVISVLGAPYFIYLLMK AN*" gene complement(3281810..3282820) /gene="fhuG" /locus_tag="BSU_33300" /old_locus_tag="BSU33300" CDS complement(3282820..3283974) /gene="fhuB" /locus_tag="BSU_33310" /old_locus_tag="BSU33310" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 8388528, 12354229, 15849754, 16850406, 24362930; Product type t : transporter" /codon_start=1 /transl_table=11 /product="ferrichrome ABC transporter (permease)" /protein_id="NP_391212.1" /db_xref="EnsemblGenomes-Gn:BSU33310" /db_xref="EnsemblGenomes-Tr:CAB15337" /db_xref="GOA:P49936" /db_xref="InterPro:IPR000522" /db_xref="InterPro:IPR035568" /db_xref="SubtiList:BG11389" /db_xref="UniProtKB/Swiss-Prot:P49936" /translation="MHFHFCSKHSIKSAEKSDILKQQLIIIISNRKEVRQLSQHKNIR TASEEIQWTSRTYGAVIVLIAGLCLLCLGAFLSISLGAADIHLRTVWEAIFHYQPTKT SHQIIHDLRLPRTAAAALVGALLAVSGAIMQGMTRNPLAEPSIMGVTSGSAFAVSIAF AFFPGLSAMGLVLWSFAGAGLGASTVMGIGMFSRGGLTPVKLALAGTAVTYFFTGIST AIAIRFDVAQDISFWYAGGVAGVKWSGVQLLLIAGAVGLTLAFFIARSVTVLSLGDDL AKGLGQYTSAVKLVGMLIVVILTGAAVSIAGTIAFIGLIIPHITRFLVGVDYRWIIPC SAVLGAVLLVFADIAARLVNAPFETPVGALTSLIGVPFFFYLARRERRGL*" gene complement(3282820..3283974) /gene="fhuB" /locus_tag="BSU_33310" /old_locus_tag="BSU33310" promotor_-10 complement(3283907..3283926) /Source="Nicolas_upshift_promotors" /id="U2610" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.58941058941059" /psig="0.994005994005994" /xcortree=2108 /SigmaFactorBS="atttttgcaaatgcattttcatttttgttcaaaacactcTAT TAAATcagctgaaaaaAGTGATATACTGAAACAGCAattgataatcattatcagtaac a" /listShort="fhuB, fhuG, fhuC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3283924) /Source="Nicolas_upshifts" /id="U2610" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.58941058941059" /psig="0.994005994005994" /xcortree=2108 /SigmaFactorBS="atttttgcaaatgcattttcatttttgttcaaaacactcTAT TAAATcagctgaaaaaAGTGATATACTGAAACAGCAattgataatcattatcagtaac a" /listShort="fhuB, fhuG, fhuC" /GFF_Attribute="listLong" promotor_-35 complement(3283938..3283945) /Source="Nicolas_upshift_promotors" /id="U2610" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.58941058941059" /psig="0.994005994005994" /xcortree=2108 /SigmaFactorBS="atttttgcaaatgcattttcatttttgttcaaaacactcTAT TAAATcagctgaaaaaAGTGATATACTGAAACAGCAattgataatcattatcagtaac a" /listShort="fhuB, fhuG, fhuC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 3283986..3283993 /Source="Nicolas_upshift_promotors" /id="U2611" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.450549450549451" /psig="0.998001998001998" /xcortree=2104 /SigmaFactorBS="acaaaaatgaaaatgcatttgcaaaaataTCGTGTCAaccgg cacttgcagTGGTATAATCACAGATGATAatgattctctttttcatctatcttttaga a" /listShort="fhuD" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3284008..3284027 /Source="Nicolas_upshift_promotors" /id="U2611" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.450549450549451" /psig="0.998001998001998" /xcortree=2104 /SigmaFactorBS="acaaaaatgaaaatgcatttgcaaaaataTCGTGTCAaccgg cacttgcagTGGTATAATCACAGATGATAatgattctctttttcatctatcttttaga a" /listShort="fhuD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3284017 /Source="Nicolas_upshifts" /id="U2611" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.450549450549451" /psig="0.998001998001998" /xcortree=2104 /SigmaFactorBS="acaaaaatgaaaatgcatttgcaaaaataTCGTGTCAaccgg cacttgcagTGGTATAATCACAGATGATAatgattctctttttcatctatcttttaga a" /listShort="fhuD" /GFF_Attribute="listLong" CDS 3284072..3285019 /gene="fhuD" /locus_tag="BSU_33320" /old_locus_tag="BSU33320" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 8388528, 12354229, 26919525; Product type t: transporter" /codon_start=1 /transl_table=11 /product="ferrichrome ABC transporter (ferrichrome-bindinglipoprotein)" /protein_id="NP_391213.1" /db_xref="EnsemblGenomes-Gn:BSU33320" /db_xref="EnsemblGenomes-Tr:CAB15338" /db_xref="GOA:P37580" /db_xref="InterPro:IPR002491" /db_xref="PDB:3G9Q" /db_xref="PDB:3HXP" /db_xref="SubtiList:BG10828" /db_xref="UniProtKB/Swiss-Prot:P37580" /translation="MTHIYKKLGAAFFALLLIAALAACGNNSESKGSASDSKGAETFT YKAENGNVKIPKHPKRVVVMADGYYGYFKTLGINVVGAPENVFKNPYYKGKTNGVENI GDGTSVEKVIDLNPDLIIVWTTQGADIKKLEKIAPTVAVKYDKLDNIEQLKEFAKMTG TEDKAEKWLAKWDKKVAAAKTKIKKAVGDKTISIMQTNGKDIYVFGKDFGRGGSIIYK DLGLQATKLTKEKAIDQGPGYTSISLEKLPDFAGDYIFAGPWQSGGDDGGVFESSIWK NLNAVKNGHVYKMDPIGFYFTDPISLEGQLEFITESLTK*" gene 3284072..3285019 /gene="fhuD" /locus_tag="BSU_33320" /old_locus_tag="BSU33320" downshifts 3284995 /Source="Nicolas_upshifts" /id="D1721" /incds=0 /nref=168 /ntot=245 /MaxReadThrough="3.82329" /MaxDrop="5.73183" /score="11.0136807" /energy="-12.1" /TU="U2611" /idTUdmin="U2611" /TUdmin="-22" /isTUend="TRUE" downshifts 3285039 /Source="Nicolas_upshifts" /id="D1722" /incds=0 /nref=1 /ntot=1 /MaxReadThrough="3.01143" /MaxDrop="4.08479" /score="11.0136807" /energy="-12.1" /TU="NA" /idTUdmin="U2611" /TUdmin=22 /isTUend="TRUE" downshifts 3285193 /Source="Nicolas_upshifts" /id="D1723" /incds=0 /nref=8 /ntot=87 /MaxReadThrough="0.219110000000001" /MaxDrop="3.67928" /score="7.53231618" /energy="-13.7" /TU="NA" /idTUdmin="U2611" /TUdmin=176 /isTUend="FALSE" CDS complement(3285254..3286663) /gene="lysP" /locus_tag="BSU_33330" /old_locus_tag="BSU33330" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2b: Function from indirect experimental evidences (e.g. phenotypes); PubMedId: 14627808, 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="lysine permease" /protein_id="NP_391214.1" /db_xref="EnsemblGenomes-Gn:BSU33330" /db_xref="EnsemblGenomes-Tr:CAB15339" /db_xref="GOA:O32204" /db_xref="InterPro:IPR002293" /db_xref="SubtiList:BG14154" /db_xref="UniProtKB/Swiss-Prot:O32204" /translation="MEQTKKWGFWLLTAFVVGNMVGSGIFSLPSSLASIASPFGATSA WLLTGAGVLMIALVFGHLSIRKPELTAGPQSYARALFSDPKKGNAAGFTMVWGYWVAS WISNVAIITSLAGYLTSFFPILVDKREMFSIGGQEVTLGQLLTFAVCTILLWGTHAIL VASINGASKLNFVTTLSKVLGFVFFIVAGLFVFQTSLFGHFYFPVQGENGTSIGIGGQ VHNAAISTLWAFVGIESAVILSGRARSQRDVKRATITGLLIALSIYIIVTLITMGVLP HDKLVGSEKPFVDVLYAIVGNAGSVIMALLAILCLFGTMLGWILLGSEVPYQAAKAGD FPAFFAKTNKKGSPVIALIITNVMSQVFIFSVISRTISDAFTFLTTAATLAYLIPYLV SAIYSLKVVIKGETYDQLKGSRVRDGLIAILACAYSVFVIVTGTADLTTFILGIGLFF VGLIVYPFVSNKFQKEKQA*" gene complement(3285254..3286663) /gene="lysP" /locus_tag="BSU_33330" /old_locus_tag="BSU33330" downshifts complement(3285269) /Source="Nicolas_upshifts" /id="D1724" /incds=0 /nref=168 /ntot=213 /MaxReadThrough="0.441040000000001" /MaxDrop="6.03347" /score="23.064706" /energy="-13.7" /TU="NA" /idTUdmin="U2613" /TUdmin=0 /isTUend="TRUE" promotor_-35 3286081..3286085 /Source="Nicolas_upshift_promotors" /id="U2612" /multdbtbs="-" /comp="M10" /sig="Sig-" /pcomp="0.3996003996004" /psig="0.3996003996004" /xcortree=1015 /SigmaFactorBS="accgggaaataaaaatgaccgaataatgacgTTTGAaacaca aacaaaccggcAACGATAAAGAAGACAAaacctaatactttagaaagcgttgtgacaa a" /listShort="S1279, yvsG" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3286103..3286119 /Source="Nicolas_upshift_promotors" /id="U2612" /multdbtbs="-" /comp="M10" /sig="Sig-" /pcomp="0.3996003996004" /psig="0.3996003996004" /xcortree=1015 /SigmaFactorBS="accgggaaataaaaatgaccgaataatgacgTTTGAaacaca aacaaaccggcAACGATAAAGAAGACAAaacctaatactttagaaagcgttgtgacaa a" /listShort="S1279, yvsG" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3286110 /Source="Nicolas_upshifts" /id="U2612" /multdbtbs="-" /comp="M10" /sig="Sig-" /pcomp="0.3996003996004" /psig="0.3996003996004" /xcortree=1015 /SigmaFactorBS="accgggaaataaaaatgaccgaataatgacgTTTGAaacaca aacaaaccggcAACGATAAAGAAGACAAaacctaatactttagaaagcgttgtgacaa a" /listShort="S1279, yvsG" /GFF_Attribute="listLong" S_feature 3286117..3287084 /Source="Nicolas_S_feature" /locus_tag="new_3420519_3421486" /HighExp="S3, S4, S7, S5, S8, S6, Etha, M9-stat, T5.0H, T4.0H" /AntisenseName="NA" /AntisenseCor="7.6401427420847101E-2" /AntisenseRegPval="-0.7" /CDS_PredictionProba="NA" /TUshortSig="Sig-" /TUshortPSig="0.4" /TUlongSig="NA" /TUlongPSig="NA" /label="S1279" downshifts complement(3286765) /Source="Nicolas_upshifts" /id="D1725" /incds=0 /nref=1 /ntot=43 /MaxReadThrough="5.98281" /MaxDrop="3.61093" /score="-2.14086757" /energy="-5" /TU="U2613,U2614" /idTUdmin="U2614" /TUdmin="-110" /isTUend="FALSE" misc_RNA complement(3286767..3286946) /gene="kswB" /locus_tag="BSU_misc_RNA_54" /product="lysine riboswitch" /experiment="publication(s) with functional evidences, PMID:22416067" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 22416067; Product type n: RNA" gene complement(3286767..3286946) /gene="kswB" /locus_tag="BSU_misc_RNA_54" promotor_-10 complement(3286976..3286993) /Source="Nicolas_upshift_promotors" /id="U2613" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.566433566433566" /psig="0.98101898101898" /xcortree=2399 /SigmaFactorBS="gcttggctctatccgtattttccatctgttccCTTTGACAga tcatcctttcttTGATAACCTTCTGGGAGTaactgaataattaaatcctcactctttc t" /listShort="NA, lysP" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3286987) /Source="Nicolas_upshifts" /id="U2613" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.566433566433566" /psig="0.98101898101898" /xcortree=2399 /SigmaFactorBS="gcttggctctatccgtattttccatctgttccCTTTGACAga tcatcctttcttTGATAACCTTCTGGGAGTaactgaataattaaatcctcactctttc t" /listShort="NA, lysP" /GFF_Attribute="listLong" promotor_-35 complement(3287008..3287015) /Source="Nicolas_upshift_promotors" /id="U2613" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.566433566433566" /psig="0.98101898101898" /xcortree=2399 /SigmaFactorBS="gcttggctctatccgtattttccatctgttccCTTTGACAga tcatcctttcttTGATAACCTTCTGGGAGTaactgaataattaaatcctcactctttc t" /listShort="NA, lysP" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 3287041 /Source="Nicolas_upshifts" /id="D1726" /incds=0 /nref=1 /ntot=10 /MaxReadThrough="3.6441" /MaxDrop="3.53891" /score="-0.527038766" /energy="-4.8" /TU="U2612" /idTUdmin="U2612" /TUdmin="-462" /isTUend="FALSE" CDS complement(3287063..3287203) /gene="sspJ" /locus_tag="BSU_33340" /old_locus_tag="BSU33340" /function="16.13: Shape" /function="16.5: Explore" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:9852018" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9852018; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="small acid-soluble spore protein" /protein_id="YP_054593.1" /db_xref="EnsemblGenomes-Gn:BSU33340" /db_xref="EnsemblGenomes-Tr:CAE01467" /db_xref="GOA:Q7WY58" /db_xref="InterPro:IPR014220" /db_xref="SubtiList:BG14174" /db_xref="UniProtKB/Swiss-Prot:Q7WY58" /translation="MGFFNKDKGKRSEKEKNVIQGALEDAGSALKDDPLQEAVQKKKN NR*" gene complement(3287063..3287203) /gene="sspJ" /locus_tag="BSU_33340" /old_locus_tag="BSU33340" downshifts complement(3287073) /Source="Nicolas_upshifts" /id="D1727" /incds=0 /nref=40 /ntot=87 /MaxReadThrough="4.06523" /MaxDrop="5.5784" /score="-1.94521013" /energy="-14.5" /TU="U2614" /idTUdmin="U2614" /TUdmin="-418" /isTUend="FALSE" upshifts complement(3287231) /Source="Nicolas_upshifts" /id="U2614" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=839 /SigmaFactorBS="gactttggacgataaaaaatatccCGCATAAtttttcaggaa aaAGGCATCTTAAAcatgtacctattttttaaaagaggtgatacgaatgggtttcttt a" /listShort="sspJ, NA" /listLong="lysP" S_feature complement(3287233..3287821) /Source="Nicolas_S_feature" /locus_tag="new_3421635_3422223_c" /HighExp="S6, S8, S7, S5, BT, G135, Diami, G180, LBGstat, S4" /AntisenseName="yvsG" /AntisenseCor="0.46604658967097301" /AntisenseRegPval="-15.2" /CDS_PredictionProba="NA" /TUshortSig="NA" /TUshortPSig="NA" /TUlongSig="NA" /TUlongPSig="NA" /label="S1280" promotor_-10 complement(3287236..3287247) /Source="Nicolas_upshift_promotors" /id="U2614" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=839 /SigmaFactorBS="gactttggacgataaaaaatatccCGCATAAtttttcaggaa aaAGGCATCTTAAAcatgtacctattttttaaaagaggtgatacgaatgggtttcttt a" /listShort="sspJ, NA" /listLong="lysP" /label="promotor_-10" promotor_-35 complement(3287261..3287267) /Source="Nicolas_upshift_promotors" /id="U2614" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=839 /SigmaFactorBS="gactttggacgataaaaaatatccCGCATAAtttttcaggaa aaAGGCATCTTAAAcatgtacctattttttaaaagaggtgatacgaatgggtttcttt a" /listShort="sspJ, NA" /listLong="lysP" /label="promotor_-35" promotor_-35 3287293..3287300 /Source="Nicolas_upshift_promotors" /id="U2615" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.82017982017982" /psig="0.997002997002997" /xcortree=2476 /SigmaFactorBS="tgaaaaattatgcgggatattttttatcgtccaaagtccTGT TGATCaaacatacattctctTGATATATTTGTAATTCAGAgattttttgcaaaagata a" /listShort="yvsG, yvgJ" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 3287314 /Source="Nicolas_upshifts" /id="U2615" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.82017982017982" /psig="0.997002997002997" /xcortree=2476 /SigmaFactorBS="tgaaaaattatgcgggatattttttatcgtccaaagtccTGT TGATCaaacatacattctctTGATATATTTGTAATTCAGAgattttttgcaaaagata a" /listShort="yvsG, yvgJ" /GFF_Attribute="listLong" promotor_-10 3287316..3287335 /Source="Nicolas_upshift_promotors" /id="U2615" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.82017982017982" /psig="0.997002997002997" /xcortree=2476 /SigmaFactorBS="tgaaaaattatgcgggatattttttatcgtccaaagtccTGT TGATCaaacatacattctctTGATATATTTGTAATTCAGAgattttttgcaaaagata a" /listShort="yvsG, yvgJ" /GFF_Attribute="listLong" /label="promotor_-10" CDS 3287370..3287852 /gene="yvsG" /locus_tag="BSU_33350" /old_locus_tag="BSU33350" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16267290, 16850406; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative membrane hydrolase" /protein_id="NP_391215.1" /db_xref="EnsemblGenomes-Gn:BSU33350" /db_xref="EnsemblGenomes-Tr:CAB15340" /db_xref="GOA:O32205" /db_xref="InterPro:IPR007404" /db_xref="InterPro:IPR016956" /db_xref="SubtiList:BG14153" /db_xref="UniProtKB/Swiss-Prot:O32205" /translation="MTGKTHIMGGIASCTAAAYYYGFDPVLMAASGAVGALIPDICHT QSKIGRKFPILSKVVSSVFGHRTFTHSLLFMLIMFFITSTYIPDKNISAGLMIGMASH LILDAWTVNGIKLLFPSTIRVRLPLYMKTGSFSEQLVLAGLTLASCYYFYMLFHGRMF *" gene 3287370..3287852 /gene="yvsG" /locus_tag="BSU_33350" /old_locus_tag="BSU33350" promotor_-35 3287866..3287873 /Source="Nicolas_upshift_promotors" /id="U2616" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.724275724275724" /psig="0.999000999001" /xcortree=1927 /SigmaFactorBS="gccgcatgttttaaacatgagtgctgaGACTTGTCtgaaccg gctgttTTTAGTAGGTTTTACTTAAGaagcatttcatgcagatgatcaagaaaacgtg a" /listShort="yvgJ" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3287887..3287906 /Source="Nicolas_upshift_promotors" /id="U2616" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.724275724275724" /psig="0.999000999001" /xcortree=1927 /SigmaFactorBS="gccgcatgttttaaacatgagtgctgaGACTTGTCtgaaccg gctgttTTTAGTAGGTTTTACTTAAGaagcatttcatgcagatgatcaagaaaacgtg a" /listShort="yvgJ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3287899 /Source="Nicolas_upshifts" /id="U2616" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.724275724275724" /psig="0.999000999001" /xcortree=1927 /SigmaFactorBS="gccgcatgttttaaacatgagtgctgaGACTTGTCtgaaccg gctgttTTTAGTAGGTTTTACTTAAGaagcatttcatgcagatgatcaagaaaacgtg a" /listShort="yvgJ" /GFF_Attribute="listLong" CDS 3287952..3289805 /gene="ltaSP" /locus_tag="BSU_33360" /old_locus_tag="BSU33360" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:15187182, 21255105, 23103977, 25288647" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15187182, 21255105, 23103977, 25288647; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="primase of polyglycerolphosphate lipoteichoic acid (LTA) synthesis" /protein_id="NP_391216.1" /db_xref="EnsemblGenomes-Gn:BSU33360" /db_xref="EnsemblGenomes-Tr:CAB15341" /db_xref="GOA:O32206" /db_xref="InterPro:IPR000917" /db_xref="InterPro:IPR012160" /db_xref="InterPro:IPR017849" /db_xref="InterPro:IPR017850" /db_xref="SubtiList:BG14092" /db_xref="UniProtKB/Swiss-Prot:O32206" /translation="MKGTFFHNQRFLCFSILFMWIKTYVIYKLGFDLQIDTLLEELML LVNPLSFILPLFGIGLFLKENKQRAFLLIANLVLTVILISNTIFYGFYIDFITIPVLF QASNMSDMGSSVKELFHPLFIALFVDLVFLLLFARKTKHPQTKAAPHTIKRYYAASCG MLLCTLALAEVQQPKLLAHSFDREMLVKSIGLFQFHIYDTISQTVNISAKAFADEDSI TAIKNYTEADYSKPDQSKFGLAKGRNVIFVTLESTQSFVLNEKVNGKEITPFMNDLIK KSYSFDHFYQQTEQGKTSDSEFIVANSLYPSLSGAVFFTKSDHQFHTMYKSLKQHDYY SAVFHANHKTFWNRDVMYDTFGIDRFFDVDDFHVTPGTSTSWGLKDKEFLEQSAKKLK SLPQPFYSSFITLTNHFPFEIDEKDQLIDEFDSSSDLLNRYVTTVRYEDEALKHFIKK LKDEGLYENSMIVFMGDHYGISEAHNEAMAEFLGKDEITPYDNVQLQRVPFIIHIPGI TDQQPETIPDAGGQVDVRPTLMHLLGVETKGDIQFGNDLLSGDRTPFAVLRNGSFITN DYVYTKNTCYSQKTGEVLEDQDACLPYKEKANEELSLSDKILNGDLLRFSE*" gene 3287952..3289805 /gene="ltaSP" /locus_tag="BSU_33360" /old_locus_tag="BSU33360" downshifts 3289791 /Source="Nicolas_upshifts" /id="D1728" /incds=0 /nref=30 /ntot=171 /MaxReadThrough="1.18268" /MaxDrop="3.6959" /score="21.1397957" /energy="-10.5" /TU="NA" /idTUdmin="U2615" /TUdmin=0 /isTUend="TRUE" CDS complement(3289833..3290759) /gene="yvgK" /locus_tag="BSU_33370" /old_locus_tag="BSU33370" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative molybdate binding regulator" /protein_id="NP_391217.1" /db_xref="EnsemblGenomes-Gn:BSU33370" /db_xref="EnsemblGenomes-Tr:CAB15342" /db_xref="GOA:O32207" /db_xref="InterPro:IPR009061" /db_xref="InterPro:IPR010093" /db_xref="InterPro:IPR024370" /db_xref="InterPro:IPR036388" /db_xref="SubtiList:BG14093" /db_xref="UniProtKB/Swiss-Prot:O32207" /translation="MNETSSYTIEEVAGLLKVSKLTVYDLIKKGVLPAYRVGRQMRVD EEDLKQYKTNMRMSQPIAAKEAPKQVQEAEPDGRPNVMISGQDISMDILSKHLENAIQ ETPLRKYKGSLNSLIDMYQGKCDIVSLHLYDAETGQYNAPYVKRILTGEPFCLINVVL RKAGLYVQKGNPKNIQGWKDLKRADIRIINREKGSGARVLLDEQLGLLGVNPADVVGY GDIVTDHYAAASQVSSGQADAGIGAQHAAHMGSVDFIPLIDEQYDIVVLKKNEQLLKA VKEILNSEDYKANLSHLNGYETKLTGKVILET*" gene complement(3289833..3290759) /gene="yvgK" /locus_tag="BSU_33370" /old_locus_tag="BSU33370" downshifts complement(3289845) /Source="Nicolas_upshifts" /id="D1729" /incds=0 /nref=232 /ntot=260 /MaxReadThrough="0.15268" /MaxDrop="6.72558" /score="21.9965704" /energy="-10.5" /TU="NA" /idTUdmin="U2617" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(3290771..3290790) /Source="Nicolas_upshift_promotors" /id="U2617" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.712287712287712" /psig="0.997002997002997" /xcortree=2738 /SigmaFactorBS="ttagatataactaattataactgattatgtttggtttatgtg gGTTTttttacattcggcgaAAAGGTATAATAAAATAGGAgagtgatgatgatgaatg a" /listShort="yvgK" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3290792) /Source="Nicolas_upshifts" /id="U2617" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.712287712287712" /psig="0.997002997002997" /xcortree=2738 /SigmaFactorBS="ttagatataactaattataactgattatgtttggtttatgtg gGTTTttttacattcggcgaAAAGGTATAATAAAATAGGAgagtgatgatgatgaatg a" /listShort="yvgK" /GFF_Attribute="listLong" promotor_-35 complement(3290806..3290809) /Source="Nicolas_upshift_promotors" /id="U2617" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.712287712287712" /psig="0.997002997002997" /xcortree=2738 /SigmaFactorBS="ttagatataactaattataactgattatgtttggtttatgtg gGTTTttttacattcggcgaAAAGGTATAATAAAATAGGAgagtgatgatgatgaatg a" /listShort="yvgK" /GFF_Attribute="listLong" /label="promotor_-35" misc_feature 3290828..3290847 /Source="Nicolas_upshift_promotors" /id="U2618" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.616383616383616" /psig="0.95104895104895" /xcortree=2395 /SigmaFactorBS="tttattataccttttcgccgaatgtaaaaaaacccacataaa ccaaacataATCAGTTATAATTAGTTATAtctaatgataaggggtgcaatcatgttta a" /listShort="yvgL, yvgM" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 3290837 /Source="Nicolas_upshifts" /id="U2618" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.616383616383616" /psig="0.95104895104895" /xcortree=2395 /SigmaFactorBS="tttattataccttttcgccgaatgtaaaaaaacccacataaa ccaaacataATCAGTTATAATTAGTTATAtctaatgataaggggtgcaatcatgttta a" /listShort="yvgL, yvgM" /GFF_Attribute="listLong" CDS 3290870..3291652 /gene="modA" /locus_tag="BSU_33380" /old_locus_tag="BSU33380" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 9302996; Product type lp : lipoprotein" /codon_start=1 /transl_table=11 /product="molybdate-binding lipoprotein" /protein_id="NP_391218.1" /db_xref="EnsemblGenomes-Gn:BSU33380" /db_xref="EnsemblGenomes-Tr:CAB15343" /db_xref="GOA:O32208" /db_xref="InterPro:IPR005950" /db_xref="SubtiList:BG14094" /db_xref="UniProtKB/Swiss-Prot:O32208" /translation="MFKKYSIFIAALTAFLLVAGCSSNQSSTDSEKKVTLTISAAASA QDALEEIQKNYEKDHQHITIQDNYGSSGALQKQISQGAGADLFFSAAEDKFKKLVDDG DIAKKDSTELVGNEIVLVVPKNGDSPVTSFSNLAESEKIALGTPESVPAGAYGKESLT KLSLWDKVKDKIVYGKDVRQVLSYVETGNVDAGVVYKTDALVSKKVNIVDEAKADTHS PIVYPLGIVKDTKHRKEAKEFYEYLQSDEAMKVFEKYGFTAE*" gene 3290870..3291652 /gene="modA" /locus_tag="BSU_33380" /old_locus_tag="BSU33380" CDS 3291624..3292316 /gene="modB" /locus_tag="BSU_33390" /old_locus_tag="BSU33390" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2b: Function from indirect experimental evidences (e.g. phenotypes); PubMedId: 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="molybdenum transport permease" /protein_id="NP_391219.3" /db_xref="EnsemblGenomes-Gn:BSU33390" /db_xref="EnsemblGenomes-Tr:CAB15344" /db_xref="GOA:O32209" /db_xref="InterPro:IPR000515" /db_xref="InterPro:IPR011867" /db_xref="InterPro:IPR035906" /db_xref="SubtiList:BG14095" /db_xref="UniProtKB/Swiss-Prot:O32209" /translation="MRNMALLPSSISASEFFTPVVLSFQVAAVAGIVVIILGTLAGAW MSRASFFGKTALETCFMLPLVLPPTVVGFILIVIFGKHSFIGQAIEWIFQQPVIFTWW AAVIASAVVAFPLMYQSAKTGFADIDPDIQGAAMVDGASRWKVFIHISVPLAYPSLLT GSILSLARALGEFGATLMFAGNIPGVTQTLPTAIYVALDSGNNTLAWAWVVCIVVISF LMLFFIQQKKTH*" gene 3291624..3292316 /gene="modB" /locus_tag="BSU_33390" /old_locus_tag="BSU33390" downshifts 3292308 /Source="Nicolas_upshifts" /id="D1730" /incds=0 /nref=40 /ntot=195 /MaxReadThrough="0.43895" /MaxDrop="4.92503" /score="19.0609965" /energy="-9.4" /TU="NA" /idTUdmin="U2618" /TUdmin=9 /isTUend="TRUE" CDS complement(3292347..3293177) /gene="pgoN" /locus_tag="BSU_33400" /old_locus_tag="BSU33400" /EC_number="1.1.1.283" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:11544192, 16232966, 17114254, 19585557" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11544192, 16232966, 17114254, 19585557; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="promiscuous glyoxal/methylglyoxal reductase" /protein_id="NP_391220.1" /db_xref="EnsemblGenomes-Gn:BSU33400" /db_xref="EnsemblGenomes-Tr:CAB15345" /db_xref="GOA:O32210" /db_xref="InterPro:IPR018170" /db_xref="InterPro:IPR020471" /db_xref="InterPro:IPR023210" /db_xref="InterPro:IPR036812" /db_xref="PDB:3D3F" /db_xref="PDB:3F7J" /db_xref="SubtiList:BG14096" /db_xref="UniProtKB/Swiss-Prot:O32210" /translation="MPTSLKDTVKLHNGVEMPWFGLGVFKVENGNEATESVKAAIKNG YRSIDTAAIYKNEEGVGIGIKESGVAREELFITSKVWNEDQGYETTLAAFEKSLERLQ LDYLDLYLIHWPGKDKYKDTWRALEKLYKDGKIRAIGVSNFQVHHLEELLKDAEIKPM VNQVEFHPRLTQKELRDYCKGQGIQLEAWSPLMQGQLLDNEVLTQIAEKHNKSVAQVI LRWDLQHGVVTIPKSIKEHRIIENADIFDFELSQEDMDKIDALNKDERVGPNPDELLF *" gene complement(3292347..3293177) /gene="pgoN" /locus_tag="BSU_33400" /old_locus_tag="BSU33400" downshifts complement(3292353) /Source="Nicolas_upshifts" /id="D1731" /incds=0 /nref=190 /ntot=269 /MaxReadThrough="4.7445" /MaxDrop="7.9269" /score="27.8070829" /energy="-9.7" /TU="U2620" /idTUdmin="U2620" /TUdmin="-528" /isTUend="FALSE" promotor_-35 3293040..3293044 /Source="Nicolas_upshift_promotors" /id="U2619" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.971028971028971" /psig="0.001998001998002" /xcortree=43 /SigmaFactorBS="catttttgtagatcgctgctgtatcaatactGCGATagccat ttttaattgCCGCTttcactgattcagtcgcttcattaccattttctactttaaaaac g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3293060..3293064 /Source="Nicolas_upshift_promotors" /id="U2619" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.971028971028971" /psig="0.001998001998002" /xcortree=43 /SigmaFactorBS="catttttgtagatcgctgctgtatcaatactGCGATagccat ttttaattgCCGCTttcactgattcagtcgcttcattaccattttctactttaaaaac g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3293069 /Source="Nicolas_upshifts" /id="U2619" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.971028971028971" /psig="0.001998001998002" /xcortree=43 /SigmaFactorBS="catttttgtagatcgctgctgtatcaatactGCGATagccat ttttaattgCCGCTttcactgattcagtcgcttcattaccattttctactttaaaaac g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" downshifts 3293179 /Source="Nicolas_upshifts" /id="D1732" /incds=0 /nref=2 /ntot=122 /MaxReadThrough="0.95687" /MaxDrop="4.12116" /score="31.5807071" /energy="-11.6" /TU="NA" /idTUdmin="U2618" /TUdmin=880 /isTUend="FALSE" promotor_-10 complement(3293207..3293226) /Source="Nicolas_upshift_promotors" /id="U2620" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.96003996003996" /psig="0.998001998001998" /xcortree=1944 /SigmaFactorBS="tgtgaaaaaagaagcaaaaagagggtcttaagcgtatTATTG GTAtcggctgagaggaaTGTGAGATAATATAGACGCTtacatttcagtgaaagggtgg a" /listShort="yvgN" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3293225) /Source="Nicolas_upshifts" /id="U2620" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.96003996003996" /psig="0.998001998001998" /xcortree=1944 /SigmaFactorBS="tgtgaaaaaagaagcaaaaagagggtcttaagcgtatTATTG GTAtcggctgagaggaaTGTGAGATAATATAGACGCTtacatttcagtgaaagggtgg a" /listShort="yvgN" /GFF_Attribute="listLong" promotor_-35 complement(3293241..3293248) /Source="Nicolas_upshift_promotors" /id="U2620" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.96003996003996" /psig="0.998001998001998" /xcortree=1944 /SigmaFactorBS="tgtgaaaaaagaagcaaaaagagggtcttaagcgtatTATTG GTAtcggctgagaggaaTGTGAGATAATATAGACGCTtacatttcagtgaaagggtgg a" /listShort="yvgN" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 3293333..3293339 /Source="Nicolas_upshift_promotors" /id="U2621" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=146 /SigmaFactorBS="caaatccaaacactatttttttcctattttaacaatattgAG ATTACaaatacattgagcaGGGTATGCGTGTAGTGTAAccaaatgaaaacaaaggagg a" /listShort="yvgO" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 3293353 /Source="Nicolas_upshifts" /id="U2621" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=146 /SigmaFactorBS="caaatccaaacactatttttttcctattttaacaatattgAG ATTACaaatacattgagcaGGGTATGCGTGTAGTGTAAccaaatgaaaacaaaggagg a" /listShort="yvgO" /GFF_Attribute="listLong" promotor_-10 3293354..3293372 /Source="Nicolas_upshift_promotors" /id="U2621" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=146 /SigmaFactorBS="caaatccaaacactatttttttcctattttaacaatattgAG ATTACaaatacattgagcaGGGTATGCGTGTAGTGTAAccaaatgaaaacaaaggagg a" /listShort="yvgO" /GFF_Attribute="listLong" /label="promotor_-10" CDS 3293400..3293885 /gene="yvgO" /locus_tag="BSU_33410" /old_locus_tag="BSU33410" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1c: Function from experimental evidences in the studied genus; PubMedId: 11988534, 22307285, 25217289; Product type f: factor" /codon_start=1 /transl_table=11 /product="exported stress induced factor" /protein_id="NP_391221.1" /db_xref="EnsemblGenomes-Gn:BSU33410" /db_xref="EnsemblGenomes-Tr:CAB15346" /db_xref="SubtiList:BG14097" /db_xref="UniProtKB/Swiss-Prot:O32211" /translation="MKRIRIPMTLALGAALTIAPLSFASAEENPAPKMSQTTTAGTTA ADVGLNVNLDVLGIANQIADAIKSAQNRDGFVKNLMESSFYASGQKYNVMVFNLSQEY EDHLNGVQFYGSAVYDGITYGIWVFEDGTFTNKGDGGWINWAFRGWFDRDGSTVAFHR P*" gene 3293400..3293885 /gene="yvgO" /locus_tag="BSU_33410" /old_locus_tag="BSU33410" downshifts 3293884 /Source="Nicolas_upshifts" /id="D1733" /incds=0 /nref=18 /ntot=93 /MaxReadThrough="3.44281" /MaxDrop="6.83046" /score="31.5807071" /energy="-11.6" /TU="U2621" /idTUdmin="U2621" /TUdmin="-571" /isTUend="FALSE" CDS complement(3293929..3295941) /gene="nhaK" /locus_tag="BSU_33420" /old_locus_tag="BSU33420" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:15849754, 16021482, 16850406, 28420751" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15849754, 16021482, 16850406, 28420751; Product type t: transporter" /codon_start=1 /transl_table=11 /product="Na+/H+ antiporter" /protein_id="NP_391222.1" /db_xref="EnsemblGenomes-Gn:BSU33420" /db_xref="EnsemblGenomes-Tr:CAB15347" /db_xref="GOA:O32212" /db_xref="InterPro:IPR004705" /db_xref="InterPro:IPR006153" /db_xref="InterPro:IPR018422" /db_xref="SubtiList:BG14098" /db_xref="UniProtKB/Swiss-Prot:O32212" /translation="MDIFLVVLVLLTIIAISNIVNRFIPFIPVPLIQVALGILAASFP QGLHFELNTELFFVLFIAPLLFNDGKRTPRAELWNLRAPILLLALGLVFATVIVGGYT IHWMIPAIPLAAAFGLAAILSPTDVVAVSALSGRVKMPKGILRLLEGEGLMNDASGLV AFKFAIAAAVTGAFSLAQAAVSFVFISLGGLLCGVVISFLIIRFRLFLRRLGMQDVTM HMLIQILTPFVIYLAAEEIGVSGILAVVAGGITHAVEQDRLESTMIKLQIVSSSTWNI ILFILNGLVFVILGTQIPDVISVIFNDTAISNMKVIGYILVITFTLMLLRFLWVLFFW NGKWFFNKDQNIYKPGLRSTLLISISGVRGAVTLAGSFSIPYFLEDGTPFPERNLILF LAAGVILCTLVIATVVLPILTEKEEEDEERNKKLLTARRKLIKTALQTIKEDMNETNK TASLAVIAEYNEKMKNLRFQQYTSSNRIKKHERKVRAQGVKAEQEALMKMLERGDIPE ETANVLQERFNELEILYANPFKVGLSKTRLKRLMYWIFFGEHKKPEMSILNEAGLIRA TRVKTAKAAIEYLEKHKTDEHKEVFLSVITFYKQLIFRLEHSHHELKSSAHFENQKLE VKLKAVQAIRNEIQTLFEEREISRDISHELRQYINDVEAAMLEGGE*" gene complement(3293929..3295941) /gene="nhaK" /locus_tag="BSU_33420" /old_locus_tag="BSU33420" downshifts complement(3293937) /Source="Nicolas_upshifts" /id="D1734" /incds=0 /nref=118 /ntot=238 /MaxReadThrough="2.66359" /MaxDrop="5.82216" /score="41.6492295" /energy="-13.2" /TU="NA" /idTUdmin="U2622" /TUdmin=0 /isTUend="TRUE" misc_feature complement(3295607..3295611) /Source="Nicolas_upshift_promotors" /id="U2622" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.403596403596404" /psig="0.04995004995005" /xcortree=1527 /SigmaFactorBS="tgtatttgcgactgtgattgtaggcggctacacgattcactg gatgattcctgctattCCGCTggcagcggcctttggacttgcggccattctttcaccg a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(3295609) /Source="Nicolas_upshifts" /id="U2622" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.403596403596404" /psig="0.04995004995005" /xcortree=1527 /SigmaFactorBS="tgtatttgcgactgtgattgtaggcggctacacgattcactg gatgattcctgctattCCGCTggcagcggcctttggacttgcggccattctttcaccg a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" S_feature complement(3295942..3296093) /Source="Nicolas_S_feature" /locus_tag="new_3430344_3430495_c" /HighExp="dia5, T0.30H, T-0.40H, Salt, Diami, T1.0H, T0.0H, T1.30H, dia15, T-1.10H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="0.746, 0.998" /TUlongSig="NA" /TUlongPSig="NA" /label="S1281" misc_feature complement(3296070..3296088) /Source="Nicolas_upshift_promotors" /id="U2623" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.341658341658342" /psig="0.746253746253746" /xcortree=1528 /SigmaFactorBS="ttctataatttgctcttctgcaaaaaagttcactgtgagcat atcatgagaaaaaataccctaaaAAGGGTACTATAAAAGAAGacaagtgtggagagaa c" /listShort="S1281, nhaK" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(3296093) /Source="Nicolas_upshifts" /id="U2623" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.341658341658342" /psig="0.746253746253746" /xcortree=1528 /SigmaFactorBS="ttctataatttgctcttctgcaaaaaagttcactgtgagcat atcatgagaaaaaataccctaaaAAGGGTACTATAAAAGAAGacaagtgtggagagaa c" /listShort="S1281, nhaK" /GFF_Attribute="listLong" CDS complement(3296196..3297911) /gene="cysI" /locus_tag="BSU_33430" /old_locus_tag="BSU33430" /EC_number="1.8.1.2" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:11445163, 12169591, 16267287" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11445163, 12169591, 16267287; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="assimilatory sulfite reductase (hemoprotein beta-subunit)" /protein_id="NP_391223.1" /db_xref="EnsemblGenomes-Gn:BSU33430" /db_xref="EnsemblGenomes-Tr:CAB15348" /db_xref="GOA:O32213" /db_xref="InterPro:IPR005117" /db_xref="InterPro:IPR006066" /db_xref="InterPro:IPR006067" /db_xref="InterPro:IPR011786" /db_xref="InterPro:IPR036136" /db_xref="SubtiList:BG14099" /db_xref="UniProtKB/Swiss-Prot:O32213" /translation="MVTKILKAPDGSPSDVERIKKESDYLRGTLKEVMLDRISAGIPD DDNRLMKHHGSYLQDDRDLRNERQKQKLEPAYQFMLRVRMPGGVSTPEQWLVMDDLSQ KYGNGTLKLTTRETFQMHGILKWNMKKTIQTIHSALLDTIAACGDVNRNVMCASNPYQ SEIHSEVYEWSKKLSDDLLPRTRAYHEIWLDEERVAGTPEEEVEPMYGPLYLPRKFKI GIAVPPSNDIDVFSQDLGFIAIVEDGKLIGFNVAIGGGMGMTHGDTATYPQLAKVIGF CRPEQMYDVAEKTITIQRDYGNRSVRKNARFKYTVDRLGLENVKEELENRLGWSLEEA KPYHFDHNGDRYGWVEGIEDKWHFTLFVEGGRITDYDDYKLMTGLREIAKVHTGEFRL TANQNLMIANVSSDKKEEISALIEQYGLTDGKHYSALRRSSMACVALPTCGLAMAEAE RYLPTLLDKIEEIIDENGLRDQEITIRMTGCPNGCARHALGEIGFIGKAPGKYNMYLG AAFDGSRLSKMYRENIGEADILSELRILLSRYAKEREEGEHFGDFVIRAGIIKATTDG TNFHD*" gene complement(3296196..3297911) /gene="cysI" /locus_tag="BSU_33430" /old_locus_tag="BSU33430" downshifts complement(3296203) /Source="Nicolas_upshifts" /id="D1735" /incds=0 /nref=211 /ntot=254 /MaxReadThrough="3.28258" /MaxDrop="6.31358" /score="23.5256972" /energy="-13.8" /TU="U2624" /idTUdmin="U2624" /TUdmin="-572" /isTUend="FALSE" CDS complement(3297937..3299754) /gene="cysJ" /locus_tag="BSU_33440" /old_locus_tag="BSU33440" /EC_number="1.8.1.2" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:11445163, 12169591, 16267287, 22720735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11445163, 12169591, 16267287, 22720735; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="assimilatory sulfite reductase (flavoprotein alpha-subunit)" /protein_id="NP_391224.1" /db_xref="EnsemblGenomes-Gn:BSU33440" /db_xref="EnsemblGenomes-Tr:CAB15349" /db_xref="GOA:O32214" /db_xref="InterPro:IPR001094" /db_xref="InterPro:IPR001433" /db_xref="InterPro:IPR001709" /db_xref="InterPro:IPR003097" /db_xref="InterPro:IPR008254" /db_xref="InterPro:IPR010199" /db_xref="InterPro:IPR017927" /db_xref="InterPro:IPR017938" /db_xref="InterPro:IPR029039" /db_xref="SubtiList:BG14100" /db_xref="UniProtKB/Swiss-Prot:O32214" /translation="MQLQVMNSPFNQEQAELLNRLLPTLTESQKIWLSGYLSAQSVSA QEAAGTPAAAVSAEAPAPAVSKEVTVLYGSQTGNAQGLAENAGKQLEQSGFQVTVSSM SDFKPNQLKKVTNLLIVVSTHGEGEPPDNALSFHEFLHGRRAPKLEDLRFSVLALGDS SYEFFCQTGKEFDQRLEELGGKRISPRVDCDLDYDEPAAEWLEGVLKGLNEAGGGSAA PAPAAASQTGESSYSRTNPFRAEVLENLNLNGRGSNKETRHVELSLEGSGLTYEPGDS LGVYPENDPELVELLLKEMNWDPEEIVTLNKQGDVRPLKEALISHYEITVLTKPLLEQ AAQLTGNDELRELLAPGNEENVKAYIEGRDLLDLVRDYGPFSVSAQEFVSILRKMPAR LYSIASSLSANPDEVHLTIGAVRYDAHGRERKGVCSILCAERLQPGDTLPVYVQHNQN FKLPKDPETPIIMVGPGTGVAPFRSFMQEREETGAEGKAWMFFGDQHFVTDFLYQTEW QNWLKDGVLTKMDVAFSRDTEEKVYVQHRMLEHSAELFEWLQEGAAVYICGDEKHMAH DVHNTLLEIIEKEGNMSREEAEAYLADMQQQKRYQRDVY*" gene complement(3297937..3299754) /gene="cysJ" /locus_tag="BSU_33440" /old_locus_tag="BSU33440" promotor_-10 complement(3299796..3299815) /Source="Nicolas_upshift_promotors" /id="U2624" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.584415584415584" /psig="0.998001998001998" /xcortree=3070 /SigmaFactorBS="ttatcattaggattcttaatagttatcatcatgtaaatatAT TTTACTtaagcctagtatTCCGGTAAAGTTCAATTAGAtgcaattttcgatcagttta t" /listShort="cysJ, cysI, S1281, nhaK" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 3299805..3299812 /Source="Nicolas_upshift_promotors" /id="U2625" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.74925074925075" /psig="0.98001998001998" /xcortree=3037 /SigmaFactorBS="atccacctcacaaagttataaactgatcgaaaattgcatcta attgaACTTTACCggaatactaggcTTAAGTAAAATATATTTACAtgatgataactat t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" upshifts complement(3299815) /Source="Nicolas_upshifts" /id="U2624" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.584415584415584" /psig="0.998001998001998" /xcortree=3070 /SigmaFactorBS="ttatcattaggattcttaatagttatcatcatgtaaatatAT TTTACTtaagcctagtatTCCGGTAAAGTTCAATTAGAtgcaattttcgatcagttta t" /listShort="cysJ, cysI, S1281, nhaK" /GFF_Attribute="listLong" upshifts 3299818 /Source="Nicolas_upshifts" /id="U2625" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.74925074925075" /psig="0.98001998001998" /xcortree=3037 /SigmaFactorBS="atccacctcacaaagttataaactgatcgaaaattgcatcta attgaACTTTACCggaatactaggcTTAAGTAAAATATATTTACAtgatgataactat t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 3299825..3299844 /Source="Nicolas_upshift_promotors" /id="U2625" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.74925074925075" /psig="0.98001998001998" /xcortree=3037 /SigmaFactorBS="atccacctcacaaagttataaactgatcgaaaattgcatcta attgaACTTTACCggaatactaggcTTAAGTAAAATATATTTACAtgatgataactat t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 complement(3299828..3299835) /Source="Nicolas_upshift_promotors" /id="U2624" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.584415584415584" /psig="0.998001998001998" /xcortree=3070 /SigmaFactorBS="ttatcattaggattcttaatagttatcatcatgtaaatatAT TTTACTtaagcctagtatTCCGGTAAAGTTCAATTAGAtgcaattttcgatcagttta t" /listShort="cysJ, cysI, S1281, nhaK" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3299925..3302249) /gene="helD" /locus_tag="BSU_33450" /old_locus_tag="BSU33450" /function="16.6: Maintain" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:11544244, 24520113" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11544244, 24520113; Product type f: factor" /codon_start=1 /transl_table=11 /product="transcription factor" /protein_id="NP_391225.1" /db_xref="EnsemblGenomes-Gn:BSU33450" /db_xref="EnsemblGenomes-Tr:CAB15350" /db_xref="GOA:O32215" /db_xref="InterPro:IPR000212" /db_xref="InterPro:IPR014016" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR027785" /db_xref="SubtiList:BG14101" /db_xref="UniProtKB/Swiss-Prot:O32215" /translation="MNQQDKEWKEEQSRIDEVLKELEKKERFLETSAGGLKHDIIGLR KSFWEDVKVNFDDAHEAIETMASIKQQAELLSDREHNHRRMDQQLKRIHQLKKSPYFG RIDFIENGEEQAERIYIGLASCLDEKEEHFLIYDWRAPISSLYYNYSPGKAEYEVPGE TIEGEMVLKRQFMIKNGTLKAMFNTDMTIGDEMLQEVLSHHSDTQMKNIVSTIQKEQN QIIRNEKSKILIVQGAAGSGKTSAALQRVAYLLYRHRGVIDAGQIVLFSPNFLFNSYV SSVLPELGEENMEQATFQEYIEHRLGRKFKCESPFDQLEYCLTETKGGDFPTRLAGIT WKAGLSFQQFINEYVTRLSSEGMIFKNIIFRGQKLITKEQIQSYFYSLDQNHSIPNRM EQTAKWLLSELNKLEKKERRKDWVVHEAELLDKEDYLDVYKKLQERKRFSESTFNDYQ REQQLLAAIIVKKAFKPLKQAVRLLAFLDVTQLYLQLFSGWGGKFQHEKMDAIGELTR SAFTDNKLLYEDAAPFLYMQDLIEGRKKNTKIKHLFIDEAQDYSPFQMAYMRSIFPAA SMTVLGDINQSIYAHTINGDQRMDACFEDEPAEYVRLKRTYRSTRQIVEFTKAMLQDG ADIEPFNRSGEMPLVVKTEGHESLCQKLAQEIGRLKKKGHETIAVICKTAHQCIQAHA HMSEYTDVRLIHKENQPFQKGVCVIPVYLAKGIEFDAVLVYDASEEHYHTEHDRRLLY TACTRAMHMLAVFYTGEASPFVTAVPPHLYQIAE*" gene complement(3299925..3302249) /gene="helD" /locus_tag="BSU_33450" /old_locus_tag="BSU33450" downshifts complement(3299943) /Source="Nicolas_upshifts" /id="D1736" /incds=0 /nref=26 /ntot=168 /MaxReadThrough="1.20405" /MaxDrop="4.59044" /score="18.6044234" /energy="-8.5" /TU="NA" /idTUdmin="U2628" /TUdmin=0 /isTUend="TRUE" promotor_-35 3302269..3302276 /Source="Nicolas_upshift_promotors" /id="U2626" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.888111888111888" /psig=1 /xcortree=3099 /SigmaFactorBS="atcctgctgattcatgaacggcacctccagaaaaTAGTTGAC aaacatagatgaaaTACTGTAAAATATAATTGGAtacatatattaaatatatgatgca a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3302291..3302310 /Source="Nicolas_upshift_promotors" /id="U2626" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.888111888111888" /psig=1 /xcortree=3099 /SigmaFactorBS="atcctgctgattcatgaacggcacctccagaaaaTAGTTGAC aaacatagatgaaaTACTGTAAAATATAATTGGAtacatatattaaatatatgatgca a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" misc_feature complement(3302292..3302307) /Source="Nicolas_upshift_promotors" /id="U2627" /multdbtbs="-" /comp="M3" /sig="Sig-" /pcomp="0.276723276723277" /psig="0.398601398601399" /xcortree=685 /SigmaFactorBS="attataaattgtatttgccagtttgcatcatatatttaatat atgtatccAATTATATTTTACAGTatttcatctatgtttgtcaactattttctggagg t" /listShort="helD" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 3302295 /Source="Nicolas_upshifts" /id="U2626" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.888111888111888" /psig=1 /xcortree=3099 /SigmaFactorBS="atcctgctgattcatgaacggcacctccagaaaaTAGTTGAC aaacatagatgaaaTACTGTAAAATATAATTGGAtacatatattaaatatatgatgca a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" upshifts complement(3302297) /Source="Nicolas_upshifts" /id="U2627" /multdbtbs="-" /comp="M3" /sig="Sig-" /pcomp="0.276723276723277" /psig="0.398601398601399" /xcortree=685 /SigmaFactorBS="attataaattgtatttgccagtttgcatcatatatttaatat atgtatccAATTATATTTTACAGTatttcatctatgtttgtcaactattttctggagg t" /listShort="helD" /GFF_Attribute="listLong" promotor_-10 complement(3302342..3302361) /Source="Nicolas_upshift_promotors" /id="U2628" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.380619380619381" /psig="0.993006993006993" /xcortree=1452 /SigmaFactorBS="ttttctgcataatataaataacccaaacCTTGATTggtattg ggtgaatgTGCTATTATAAATTGTATTTgccagtttgcatcatatatttaatatatgt a" /listShort="helD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3302351) /Source="Nicolas_upshifts" /id="U2628" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.380619380619381" /psig="0.993006993006993" /xcortree=1452 /SigmaFactorBS="ttttctgcataatataaataacccaaacCTTGATTggtattg ggtgaatgTGCTATTATAAATTGTATTTgccagtttgcatcatatatttaatatatgt a" /listShort="helD" /GFF_Attribute="listLong" promotor_-35 complement(3302377..3302383) /Source="Nicolas_upshift_promotors" /id="U2628" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.380619380619381" /psig="0.993006993006993" /xcortree=1452 /SigmaFactorBS="ttttctgcataatataaataacccaaacCTTGATTggtattg ggtgaatgTGCTATTATAAATTGTATTTgccagtttgcatcatatatttaatatatgt a" /listShort="helD" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(3302387..3302406) /Source="Nicolas_upshift_promotors" /id="U2629" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.854145854145854" /psig="0.854145854145854" /xcortree=1255 /SigmaFactorBS="tcttttcgcttagataattaatagcaaaaaaaccgatttCGA AGTGAAatcggtttttttcTGCATAATATAAATAACCCAaaccttgattggtattggg t" /listShort="helD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3302407) /Source="Nicolas_upshifts" /id="U2629" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.854145854145854" /psig="0.854145854145854" /xcortree=1255 /SigmaFactorBS="tcttttcgcttagataattaatagcaaaaaaaccgatttCGA AGTGAAatcggtttttttcTGCATAATATAAATAACCCAaaccttgattggtattggg t" /listShort="helD" /GFF_Attribute="listLong" promotor_-35 complement(3302420..3302428) /Source="Nicolas_upshift_promotors" /id="U2629" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.854145854145854" /psig="0.854145854145854" /xcortree=1255 /SigmaFactorBS="tcttttcgcttagataattaatagcaaaaaaaccgatttCGA AGTGAAatcggtttttttcTGCATAATATAAATAACCCAaaccttgattggtattggg t" /listShort="helD" /GFF_Attribute="listLong" /label="promotor_-35" downshifts complement(3302434) /Source="Nicolas_upshifts" /id="D1737" /incds=0 /nref=19 /ntot=158 /MaxReadThrough="2.30604" /MaxDrop="4.26839" /score="16.6103553" /energy="-9.2" /TU="NA" /idTUdmin="U2630" /TUdmin=17 /isTUend="TRUE" CDS complement(3302447..3303055) /gene="yvgT" /locus_tag="BSU_33460" /old_locus_tag="BSU33460" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative integral membrane protein" /protein_id="NP_391226.1" /db_xref="EnsemblGenomes-Gn:BSU33460" /db_xref="EnsemblGenomes-Tr:CAB15351" /db_xref="GOA:O32216" /db_xref="InterPro:IPR005115" /db_xref="SubtiList:BG14102" /db_xref="UniProtKB/Swiss-Prot:O32216" /translation="MAWELLSVIGIIAFAVSGAIVAMEEEYDILGVYILGIVTAFGGG AIRNLLIGVPVSALWEQGAYFQIALLSITIVFLFPKLLLKHWNKWGNLSDAIGLAAFA IQGALYAVKMGHPLSAVIVAAVLTGSGGGIIRDLLAGRKPLVLKAEIYAVWAALGGLI VGLGWLGNSFGLYVLFFVLVVCRVCSYMFNWKLPNRSFRLDN*" gene complement(3302447..3303055) /gene="yvgT" /locus_tag="BSU_33460" /old_locus_tag="BSU33460" promotor_-10 complement(3303094..3303113) /Source="Nicolas_upshift_promotors" /id="U2630" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.642357642357642" /psig=1 /xcortree=2617 /SigmaFactorBS="attccctctaaatttatctttttttctcatgaaaatgtTATT GattttacgctggagcGATTATAAAATCTAGAGGTCgtcagaaaatttaacaaacata a" /listShort="yvgT" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3303111) /Source="Nicolas_upshifts" /id="U2630" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.642357642357642" /psig=1 /xcortree=2617 /SigmaFactorBS="attccctctaaatttatctttttttctcatgaaaatgtTATT GattttacgctggagcGATTATAAAATCTAGAGGTCgtcagaaaatttaacaaacata a" /listShort="yvgT" /GFF_Attribute="listLong" promotor_-35 complement(3303129..3303133) /Source="Nicolas_upshift_promotors" /id="U2630" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.642357642357642" /psig=1 /xcortree=2617 /SigmaFactorBS="attccctctaaatttatctttttttctcatgaaaatgtTATT GattttacgctggagcGATTATAAAATCTAGAGGTCgtcagaaaatttaacaaacata a" /listShort="yvgT" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3303242..3303658) /gene="bdbC" /locus_tag="BSU_33470" /old_locus_tag="BSU33470" /function="16.6: Maintain" /function="16.13: Shape" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:10455116, 11872755, 15661011, 15849754, 16751195, 16850406, 17088376" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10455116, 11872755, 15661011, 15849754, 16751195, 16850406, 17088376; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="thiol-disulfide oxidoreductase" /protein_id="NP_391227.1" /db_xref="EnsemblGenomes-Gn:BSU33470" /db_xref="EnsemblGenomes-Tr:CAB15352" /db_xref="GOA:O32217" /db_xref="InterPro:IPR003752" /db_xref="InterPro:IPR012187" /db_xref="InterPro:IPR023380" /db_xref="SubtiList:BG14103" /db_xref="UniProtKB/Swiss-Prot:O32217" /translation="MKNRIVFLYASWVVALIAMLGSLYFSEIRKFIPCELCWYQRILM YPLVLILGIATFQGDTRVKKYVLPMAIIGAFISIMHYLEQKVPGFSGIKPCVSGVPCS GQYINWFGFITIPFLALIAFILIIIFMCLLKGEKSE*" gene complement(3303242..3303658) /gene="bdbC" /locus_tag="BSU_33470" /old_locus_tag="BSU33470" downshifts complement(3303252) /Source="Nicolas_upshifts" /id="D1738" /incds=0 /nref=120 /ntot=264 /MaxReadThrough="1.31968" /MaxDrop="6.21723" /score="26.5991603" /energy="-12.7" /TU="NA" /idTUdmin="U2631" /TUdmin="-9" /isTUend="TRUE" CDS complement(3303663..3304331) /gene="bdbD" /locus_tag="BSU_33480" /old_locus_tag="BSU33480" /function="16.13: Shape" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:11744713, 11872755, 12637552, 15661011, 17501922, 19535335" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11744713, 11872755, 12637552, 15661011, 17501922, 19535335; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="thiol-disulfide oxidoreductase" /protein_id="NP_391228.1" /db_xref="EnsemblGenomes-Gn:BSU33480" /db_xref="EnsemblGenomes-Tr:CAB15353" /db_xref="GOA:O32218" /db_xref="InterPro:IPR012336" /db_xref="InterPro:IPR013766" /db_xref="InterPro:IPR036249" /db_xref="PDB:3EU3" /db_xref="PDB:3EU4" /db_xref="PDB:3GH9" /db_xref="PDB:3GHA" /db_xref="SubtiList:BG14104" /db_xref="UniProtKB/Swiss-Prot:O32218" /translation="MKKKQQSSAKFAVILTVVVVVLLAAIVIINNKTEQGNDAVSGQP SIKGQPVLGKDDAPVTVVEFGDYKCPSCKVFNSDIFPKIQKDFIDKGDVKFSFVNVMF HGKGSRLAALASEEVWKEDPDSFWDFHEKLFEKQPDTEQEWVTPGLLGDLAKSTTKIK PETLKENLDKETFASQVEKDSDLNQKMNIQATPTIYVNDKVIKNFADYDEIKETIEKE LKGK*" gene complement(3303663..3304331) /gene="bdbD" /locus_tag="BSU_33480" /old_locus_tag="BSU33480" promotor_-10 complement(3304383..3304402) /Source="Nicolas_upshift_promotors" /id="U2631" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.414585414585415" /psig="0.998001998001998" /xcortree=2707 /SigmaFactorBS="acaaataaattgtcggagagaattcattttttcggggTTTTC TtatcagcgcttgtCTTGTTAAAATAAAGAAGTGggtcaattgcgatccgcttctttt t" /listShort="bdbD, bdbC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3304398) /Source="Nicolas_upshifts" /id="U2631" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.414585414585415" /psig="0.998001998001998" /xcortree=2707 /SigmaFactorBS="acaaataaattgtcggagagaattcattttttcggggTTTTC TtatcagcgcttgtCTTGTTAAAATAAAGAAGTGggtcaattgcgatccgcttctttt t" /listShort="bdbD, bdbC" /GFF_Attribute="listLong" downshifts complement(3304409) /Source="Nicolas_upshifts" /id="D1739" /incds=0 /nref=3 /ntot=9 /MaxReadThrough="7.34296" /MaxDrop="3.6233" /score="12.4442247" /energy="-11.3" /TU="U2632" /idTUdmin="U2633" /TUdmin=0 /isTUend="TRUE" promotor_-35 complement(3304416..3304421) /Source="Nicolas_upshift_promotors" /id="U2631" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.414585414585415" /psig="0.998001998001998" /xcortree=2707 /SigmaFactorBS="acaaataaattgtcggagagaattcattttttcggggTTTTC TtatcagcgcttgtCTTGTTAAAATAAAGAAGTGggtcaattgcgatccgcttctttt t" /listShort="bdbD, bdbC" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3304451..3306559) /gene="cadA" /locus_tag="BSU_33490" /old_locus_tag="BSU33490" /EC_number="3.6.3.3" /EC_number="3.6.3.5" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:7721839, 8037745, 11934502, 11922674, 12644235, 12779235, 14663075, 16901659" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7721839, 8037745, 11934502, 11922674, 12644235, 12779235, 14663075, 16901659; Product type t: transporter" /codon_start=1 /transl_table=11 /product="Cd(II), Zn(II) and Co(II) exporter (ATPase)" /protein_id="NP_391229.3" /db_xref="EnsemblGenomes-Gn:BSU33490" /db_xref="EnsemblGenomes-Tr:CAB15354" /db_xref="GOA:O32219" /db_xref="InterPro:IPR001757" /db_xref="InterPro:IPR006121" /db_xref="InterPro:IPR008250" /db_xref="InterPro:IPR017969" /db_xref="InterPro:IPR018303" /db_xref="InterPro:IPR023214" /db_xref="InterPro:IPR023298" /db_xref="InterPro:IPR023299" /db_xref="InterPro:IPR027256" /db_xref="InterPro:IPR036163" /db_xref="InterPro:IPR036412" /db_xref="SubtiList:BG14105" /db_xref="UniProtKB/Swiss-Prot:O32219" /translation="MRLVKQEYVLDGLDCSNCARKIENGVKGIKGINGCAVNFAASTL TVSADGKEEQWVTNKVEKKVKSIDPHVTVRQKHIKKSADDGYRNRMVNMLIRMAAAVI LGAAAYLVQSGTIEFFLFLGAYLIIGGDIIIRAVKNIIRGQVFDEHFLMALATIGAFL IQQYPEGVAVMLFYQIGELFQGAAVSRSRKSISALMDIRPDYANLKTKNGIEQVSSED VQTGDIIVVNPGESIPLDGKVVQGSAMVDTSALTGESVPRKAAEGQDVMSGFINQNGV LHIEVTKGYQESAVSKILDLVQNASSRKARTENFITKFAKYYTPAVVIIAVLLAFVPP LVLSGAALSDWVYRALIFLVISCPCALVVSIPLGFFGGIGAASKAGVLVKGSNYLEAL NQVKYAVFDKTGTLTKGSFEVTEIKPAEGFTKDRLLEAAAYAELHSQHPIAESVRKAY GKMLSSDEIESYEEISGHGIFAKVNGTEILAGNKKLMEREQIEDVPDENAGTIVHVAV DQRYAGAIIIADEIKEDAAQAVADLKSLGIKQTAMLTGDSKQTGEAVGKQLGIGEVYA ELLPQDKVAQVEALEAKLLPSEKLIFVGDGINDTPVLARADIGVAMGGLGSDAAVEAA DIVLMTDQPSKIAEAIRIAKRTRRIVWQNIGFALGVKAIFLILGAFGIATMWEAVFSD VGVTLLAVANAMRVMRLKNK*" gene complement(3304451..3306559) /gene="cadA" /locus_tag="BSU_33490" /old_locus_tag="BSU33490" S_feature complement(3306551..3306652) /Source="Nicolas_S_feature" /locus_tag="new_3440953_3441054_c" /HighExp="dia5, LBGtran, LBGstat, Diami, LBGexp, Gly, Lbtran, T0.30H, M40t45, M0t45" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="0.982, 0.999" /TUlongSig="SigB" /TUlongPSig="0.587" /label="S1282" promotor_-10 complement(3306646..3306665) /Source="Nicolas_upshift_promotors" /id="U2632" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.576423576423576" /psig="0.982017982017982" /xcortree=1542 /SigmaFactorBS="ggctatatgccggtttttgtttttCATTGACActttcttgga aaacaACATATAATAGGTGTAACTTatatatgagtatatgctcatatatataaaataa a" /listShort="S1282, copB, bdbD, bdbC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3306652) /Source="Nicolas_upshifts" /id="U2632" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.576423576423576" /psig="0.982017982017982" /xcortree=1542 /SigmaFactorBS="ggctatatgccggtttttgtttttCATTGACActttcttgga aaacaACATATAATAGGTGTAACTTatatatgagtatatgctcatatatataaaataa a" /listShort="S1282, copB, bdbD, bdbC" /GFF_Attribute="listLong" promotor_-35 complement(3306681..3306688) /Source="Nicolas_upshift_promotors" /id="U2632" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.576423576423576" /psig="0.982017982017982" /xcortree=1542 /SigmaFactorBS="ggctatatgccggtttttgtttttCATTGACActttcttgga aaacaACATATAATAGGTGTAACTTatatatgagtatatgctcatatatataaaataa a" /listShort="S1282, copB, bdbD, bdbC" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3306719..3309127) /gene="copA" /locus_tag="BSU_33500" /old_locus_tag="BSU33500" /EC_number="3.6.3.54" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:11922674, 11934502, 12644235, 14663075, 18215122, 19378562, 19751213, 20233928, 22077885, 22531974" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11922674, 11934502, 12644235, 14663075, 18215122, 19378562, 19751213, 20233928, 22077885, 22531974; Product type t : transporter" /codon_start=1 /transl_table=11 /product="copper transporter ATPase" /protein_id="NP_391230.2" /db_xref="EnsemblGenomes-Gn:BSU33500" /db_xref="EnsemblGenomes-Tr:CAB15355" /db_xref="GOA:O32220" /db_xref="InterPro:IPR001757" /db_xref="InterPro:IPR006121" /db_xref="InterPro:IPR006122" /db_xref="InterPro:IPR008250" /db_xref="InterPro:IPR017969" /db_xref="InterPro:IPR018303" /db_xref="InterPro:IPR023214" /db_xref="InterPro:IPR023298" /db_xref="InterPro:IPR023299" /db_xref="InterPro:IPR027256" /db_xref="InterPro:IPR036163" /db_xref="InterPro:IPR036412" /db_xref="PDB:1JWW" /db_xref="PDB:1KQK" /db_xref="PDB:1OPZ" /db_xref="PDB:1OQ3" /db_xref="PDB:1OQ6" /db_xref="PDB:1P6T" /db_xref="PDB:2RML" /db_xref="PDB:2VOY" /db_xref="SubtiList:BG14106" /db_xref="UniProtKB/Swiss-Prot:O32220" /translation="MSEQKEIAMQVSGMTCAACAARIEKGLKRMPGVTDANVNLATET SNVIYDPAETGTAAIQEKIEKLGYHVVTEKAEFDIEGMTCAACANRIEKRLNKIEGVA NAPVNFALETVTVEYNPKEASVSDLKEAVDKLGYKLKLKGEQDSEAAAKKKEERKQTA RLIFSAVLSFPLLWAMVSHFTFTSFIWVPDIFLNPWMQFALATPVQFLIGWPFYVGAY KALRNKSANMDVLVALGTTAAYAYSLYLTFQSIGSHGHTDGLYYETSAILLTLILLGK LFETKAKGRSSDAIKKLMKLQAKTATVVRDGQEQIIPIDEVLVNDIVYVKPGERIPVD GEVVEGRSAVDESMITGESLPVDKNPGDSVTGSTVNANGFLKIKAVNVGKDTALSHII KIVEEAQGSKAPIQRLADQISGIFVPIVLGIAVLTFLIWYLWAAPGDFAEAISKFIAV LVIACPCALGLATPTSIMAGSGRAAEFGILFKGGEHLEKTHRLDTIVLDKTGTVTNGK PRLTDAIPFGRFEEKDLLQFAAAAETGSEHPLGEAIIAGVKDKGLEIPKLTRFEAKVG AGILAEAGGKSILVGTRKLMESEQVEHGALLAQMEELEAEGKTVMLVSIDGEAAGLVA VADTIKDTSRKAVARLKELGLDVIMMTGDNRRTAEAIAKEAGIANIIAEVLPEQKAAE IARLQKEGRQTAMVGDGINDAPALATADIGMAIGTGTDIAMETADITLIRGDLNSIAD AIRMSRLTMKNIKQNLFWALGYNSLGIPIAALGFLAPWIAGAAMAFSSVSVVLNALRL QKVK*" gene complement(3306719..3309127) /gene="copA" /locus_tag="BSU_33500" /old_locus_tag="BSU33500" downshifts complement(3306741) /Source="Nicolas_upshifts" /id="D1740" /incds=0 /nref=15 /ntot=68 /MaxReadThrough="5.02116" /MaxDrop="3.63756" /score="26.9828242" /energy="-7.9" /TU="U2633" /idTUdmin="U2635" /TUdmin=0 /isTUend="TRUE" downshifts complement(3306807) /Source="Nicolas_upshifts" /id="D1741" /incds=1 /nref=52 /ntot=227 /MaxReadThrough="5.93949" /MaxDrop="4.28993" /score="26.9828242" /energy="-7.9" /TU="U2633,U2635" /idTUdmin="U2635" /TUdmin="-66" /isTUend="FALSE" S_feature complement(3309128..3309210) /Source="Nicolas_S_feature" /locus_tag="new_3443530_3443612_c" /HighExp="Diami, dia5, dia15, Gly, T0.30H, Heat, T1.0H, T1.30H, T0.0H, LPhT" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigB" /TUshortPSig="0.999, 0.587" /TUlongSig="NA" /TUlongPSig="NA" /label="S1283" CDS complement(3309211..3309420) /gene="copZ" /locus_tag="BSU_33510" /old_locus_tag="BSU33510" /function="16.1: Circulate" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:11934502, 12238948, 12590580, 14621987, 14663075, 15212800, 18419582, 27197762, 28078344" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11934502, 12238948, 12590580, 14621987, 14663075, 15212800, 18419582, 27197762, 28078344; Product type f: factor" /codon_start=1 /transl_table=11 /product="copper insertion chaperone and transporter component" /protein_id="NP_391231.1" /db_xref="EnsemblGenomes-Gn:BSU33510" /db_xref="EnsemblGenomes-Tr:CAB15356" /db_xref="GOA:O32221" /db_xref="InterPro:IPR000428" /db_xref="InterPro:IPR006121" /db_xref="InterPro:IPR006122" /db_xref="InterPro:IPR017969" /db_xref="InterPro:IPR036163" /db_xref="PDB:1K0V" /db_xref="PDB:1P8G" /db_xref="PDB:2QIF" /db_xref="PDB:3I9Z" /db_xref="SubtiList:BG14107" /db_xref="UniProtKB/Swiss-Prot:O32221" /translation="MEQKTLQVEGMSCQHCVKAVETSVGELDGVSAVHVNLEAGKVDV SFDADKVSVKDIADAIEDQGYDVAK*" gene complement(3309211..3309420) /gene="copZ" /locus_tag="BSU_33510" /old_locus_tag="BSU33510" promotor_-10 complement(3309444..3309463) /Source="Nicolas_upshift_promotors" /id="U2633" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.74925074925075" /psig="0.999000999001" /xcortree=1766 /SigmaFactorBS="tggacgtatttaaaaagttcacaaaatcataaagcgtttttt aTTGTAATaccctacgggggTATGGTAGGATGAAAATAGAaagaataaacaggaggaa t" /listShort="copZ, S1283, copA, S1282, copB" /listLong="bdbD, bdbC" /label="promotor_-10" upshifts complement(3309465) /Source="Nicolas_upshifts" /id="U2633" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.74925074925075" /psig="0.999000999001" /xcortree=1766 /SigmaFactorBS="tggacgtatttaaaaagttcacaaaatcataaagcgtttttt aTTGTAATaccctacgggggTATGGTAGGATGAAAATAGAaagaataaacaggaggaa t" /listShort="copZ, S1283, copA, S1282, copB" /listLong="bdbD, bdbC" promotor_-35 complement(3309476..3309482) /Source="Nicolas_upshift_promotors" /id="U2633" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.74925074925075" /psig="0.999000999001" /xcortree=1766 /SigmaFactorBS="tggacgtatttaaaaagttcacaaaatcataaagcgtttttt aTTGTAATaccctacgggggTATGGTAGGATGAAAATAGAaagaataaacaggaggaa t" /listShort="copZ, S1283, copA, S1282, copB" /listLong="bdbD, bdbC" /label="promotor_-35" CDS complement(3309494..3309799) /gene="csoR" /locus_tag="BSU_33520" /old_locus_tag="BSU33520" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:17143269, 18048925, 22904286, 24831014, 25209494" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 17143269, 18048925, 22904286, 24831014, 25209494; Product type r: regulator" /codon_start=1 /transl_table=11 /product="repressor of copper utilisation proteins-Cu(I)" /protein_id="NP_391232.1" /db_xref="EnsemblGenomes-Gn:BSU33520" /db_xref="EnsemblGenomes-Tr:CAB15357" /db_xref="GOA:O32222" /db_xref="InterPro:IPR003735" /db_xref="SubtiList:BG14108" /db_xref="UniProtKB/Swiss-Prot:O32222" /translation="MEKHNEHKTLNHKSSKEKDQITNRLKRIEGQVRGIQNMVENDRY CVDILVQISAVQAAMKNVALHLLEDHAHHCVADAIKSGDGEQAISELLDVFKKFTKS* " gene complement(3309494..3309799) /gene="csoR" /locus_tag="BSU_33520" /old_locus_tag="BSU33520" misc_feature 3309763..3309782 /Source="Nicolas_upshift_promotors" /id="U2634" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.877122877122877" /psig="0.986013986013986" /xcortree=2475 /SigmaFactorBS="tcaatccgcttaagccggtttgtaatctgatccttttctttc gagctttTATGGTTTAATGTTTTATGTtcgttatgcttttccatgcgtacacctctgt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 3309774 /Source="Nicolas_upshifts" /id="U2634" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.877122877122877" /psig="0.986013986013986" /xcortree=2475 /SigmaFactorBS="tcaatccgcttaagccggtttgtaatctgatccttttctttc gagctttTATGGTTTAATGTTTTATGTtcgttatgcttttccatgcgtacacctctgt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 complement(3309813..3309832) /Source="Nicolas_upshift_promotors" /id="U2635" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.587412587412587" /psig="0.587412587412587" /xcortree=130 /SigmaFactorBS="ggtaaaacctaactgattcattttttgcgtcggcatgcttag acaacCGTTTGGacaatcagtataaTGGGAATTAATATCATTAAAcagaggtgtacgc a" /listShort="csoR, copZ, S1283, copA" /listLong="S1282, copB, bdbD, bdbC" /label="promotor_-10" upshifts complement(3309839) /Source="Nicolas_upshifts" /id="U2635" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.587412587412587" /psig="0.587412587412587" /xcortree=130 /SigmaFactorBS="ggtaaaacctaactgattcattttttgcgtcggcatgcttag acaacCGTTTGGacaatcagtataaTGGGAATTAATATCATTAAAcagaggtgtacgc a" /listShort="csoR, copZ, S1283, copA" /listLong="S1282, copB, bdbD, bdbC" promotor_-35 complement(3309846..3309852) /Source="Nicolas_upshift_promotors" /id="U2635" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.587412587412587" /psig="0.587412587412587" /xcortree=130 /SigmaFactorBS="ggtaaaacctaactgattcattttttgcgtcggcatgcttag acaacCGTTTGGacaatcagtataaTGGGAATTAATATCATTAAAcagaggtgtacgc a" /listShort="csoR, copZ, S1283, copA" /listLong="S1282, copB, bdbD, bdbC" /label="promotor_-35" promotor_-35 3309891..3309897 /Source="Nicolas_upshift_promotors" /id="U2636" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.952047952047952" /psig="0.952047952047952" /xcortree=133 /SigmaFactorBS="aagcatgccgacgcaaaaaatgaatcagttaGGTTTTAccat ttgatcaggaGGGTATATACTTCTGTTGAtaacgcttttaaaggggagaagaaaagtg g" /listShort="yvaA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3309912..3309930 /Source="Nicolas_upshift_promotors" /id="U2636" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.952047952047952" /psig="0.952047952047952" /xcortree=133 /SigmaFactorBS="aagcatgccgacgcaaaaaatgaatcagttaGGTTTTAccat ttgatcaggaGGGTATATACTTCTGTTGAtaacgcttttaaaggggagaagaaaagtg g" /listShort="yvaA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3309920 /Source="Nicolas_upshifts" /id="U2636" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.952047952047952" /psig="0.952047952047952" /xcortree=133 /SigmaFactorBS="aagcatgccgacgcaaaaaatgaatcagttaGGTTTTAccat ttgatcaggaGGGTATATACTTCTGTTGAtaacgcttttaaaggggagaagaaaagtg g" /listShort="yvaA" /GFF_Attribute="listLong" CDS 3309927..3311003 /gene="iolW" /locus_tag="BSU_33530" /old_locus_tag="BSU33530" /EC_number="1.1.1.371" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:15937154, 20133360, 28693424" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15937154, 20133360, 28693424; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="scyllo-inositol 2-dehydrogenase (NADP(+)-dependent)" /protein_id="NP_391233.1" /db_xref="EnsemblGenomes-Gn:BSU33530" /db_xref="EnsemblGenomes-Tr:CAB15358" /db_xref="GOA:O32223" /db_xref="InterPro:IPR000683" /db_xref="InterPro:IPR004104" /db_xref="InterPro:IPR036291" /db_xref="PDB:3GDO" /db_xref="PDB:3GFG" /db_xref="SubtiList:BG14057" /db_xref="UniProtKB/Swiss-Prot:O32223" /translation="MITLLKGRRKVDTIKVGILGYGLSGSVFHGPLLDVLDEYQISKI MTSRTEEVKRDFPDAEVVHELEEITNDPAIELVIVTTPSGLHYEHTMACIQAGKHVVM EKPMTATAEEGETLKRAADEKGVLLSVYHNRRWDNDFLTIKKLISEGSLEDINTYQVS YNRYRPEVQARWREKEGTATGTLYDLGSHIIDQTLHLFGMPKAVTANVMAQRENAETV DYFHLTLDYGKLQAILYGGSIVPANGPRYQIHGKDSSFIKYGIDGQEDALRAGRKPED DSWGADVPEFYGKLTTIRGSDKKTETIPSVNGSYLTYYRKIAESIREGAALPVTAEEG INVIRIIEAAMESSKEKRTIMLEH*" gene 3309927..3311003 /gene="iolW" /locus_tag="BSU_33530" /old_locus_tag="BSU33530" downshifts 3310990 /Source="Nicolas_upshifts" /id="D1742" /incds=0 /nref=155 /ntot=248 /MaxReadThrough="2.17322" /MaxDrop="6.48885" /score="-5.36701412" /energy="-19.4" /TU="NA" /idTUdmin="U2636" /TUdmin="-9" /isTUend="TRUE" CDS complement(3311040..3311675) /gene="azoRB" /locus_tag="BSU_33540" /old_locus_tag="BSU33540" /function="16.11: Scavenge (Catabolism)" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:17284825, 17725564, 18208493" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 17284825, 17725564, 18208493; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="NADH:dichloroindophenol oxidoreductase (2-methylhydroquinone resistance)" /protein_id="NP_391234.1" /db_xref="EnsemblGenomes-Gn:BSU33540" /db_xref="EnsemblGenomes-Tr:CAB15359" /db_xref="GOA:O32224" /db_xref="InterPro:IPR003680" /db_xref="InterPro:IPR023048" /db_xref="InterPro:IPR029039" /db_xref="SubtiList:BG14058" /db_xref="UniProtKB/Swiss-Prot:O32224" /translation="MAKVLYITAHPHDEATSYSMATGKAFIESYKEANPNDEVVHIDL YKENIPHIDADVFSGWGKLQSGTGFEELSESEKAKVGRLGELSDQFASADKYVFVTPL WNFSFPPVMKAYLDSVAVAGKSFKYTEQGPVGLLTDKKAIHIQARGGYYSEGPAAEME MGHRYIGIMMNFFGVPSFDGIFVEGHNAEPDKAQQIKEDAIARAKEAGKTF*" gene complement(3311040..3311675) /gene="azoRB" /locus_tag="BSU_33540" /old_locus_tag="BSU33540" downshifts complement(3311053) /Source="Nicolas_upshifts" /id="D1743" /incds=0 /nref=211 /ntot=263 /MaxReadThrough="1.58189" /MaxDrop="6.89477" /score="31.0885268" /energy="-15.4" /TU="NA" /idTUdmin="U2637" /TUdmin=0 /isTUend="TRUE" S_feature complement(3311676..3311773) /Source="Nicolas_S_feature" /locus_tag="new_3446078_3446175_c" /HighExp="Heat, UNK1, G/S, Salt, HiTm, GM-0.1, MG 25, SMM, Etha, Glucon" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1284" promotor_-10 complement(3311753..3311772) /Source="Nicolas_upshift_promotors" /id="U2637" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.431568431568432" /psig=1 /xcortree=3022 /SigmaFactorBS="ctgtttgggaaagttaaataatctttaattcgagatgttttA CTTGAAagtaaatttctttGTCTCTATAATAAAGTCTAAgagagacagaataatcatt a" /listShort="S1284, yvaB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3311773) /Source="Nicolas_upshifts" /id="U2637" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.431568431568432" /psig=1 /xcortree=3022 /SigmaFactorBS="ctgtttgggaaagttaaataatctttaattcgagatgttttA CTTGAAagtaaatttctttGTCTCTATAATAAAGTCTAAgagagacagaataatcatt a" /listShort="S1284, yvaB" /GFF_Attribute="listLong" promotor_-35 complement(3311786..3311792) /Source="Nicolas_upshift_promotors" /id="U2637" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.431568431568432" /psig=1 /xcortree=3022 /SigmaFactorBS="ctgtttgggaaagttaaataatctttaattcgagatgttttA CTTGAAagtaaatttctttGTCTCTATAATAAAGTCTAAgagagacagaataatcatt a" /listShort="S1284, yvaB" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3311835..3313730) /gene="yvaC" /locus_tag="BSU_33550" /old_locus_tag="BSU33550" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 12107147, 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative integral inner membrane protein" /protein_id="NP_391235.1" /db_xref="EnsemblGenomes-Gn:BSU33550" /db_xref="EnsemblGenomes-Tr:CAB15360" /db_xref="GOA:O32225" /db_xref="SubtiList:BG14059" /db_xref="UniProtKB/Swiss-Prot:O32225" /translation="MNKTAANNQRIMPIVKDAFRIHANPFPWKKAIGSGFASGFPVLV GALAGHTDYGLIASIGGFVYLYAGGESYKKRALKLLLVSIGIALSFGLGTLLSGMLWM MAAVLGLIGAAAMFIFSALGIQGPAPMFFVLAFLVSSGLPADPSQALFRAGLTFLGGI FAMGIALIGWLWNKHGPEGAVLQKTYHQLAACLSAVGTPGFHNAQHQTVLMLRTARQT VLGKGNRRKKSRHDERFFRLLEKADDIFIAIIHFSAETPDRETAQIEKALRQTGDMLA NARVFNTFQINENESEPRRKLFEEINEVLYIASGRFDKQLDGEPSRLPSSFYFLRNAF DWKSPVLIRALKYGIVLFAADMFALAFGFARSYWIPLSAAAVMLGTTVVFTLHRAIQR SAGTVIGVILAGAILFFKPGGVYIAFCIAALQCLLEMLIVRNYALAVPFLTANALVIT ESMHGGAGAGYFMIARLTDVAVGSVIGLLGTMLLWRRFSTKRLPELVRNVIRLEGQFM EKLLTGQIADEHKLRVSLVRLRDAYDKALGEFPHANADALWPAISGAQHLGYYLLSAQ AHRRPSAPFSDEEINQLRAFFEQAEQSFIMKRMPADIQVPHVPHYPRISKELSALYSG LRTAFEK*" gene complement(3311835..3313730) /gene="yvaC" /locus_tag="BSU_33550" /old_locus_tag="BSU33550" promotor_-10 complement(3313781..3313792) /Source="Nicolas_upshift_promotors" /id="U2638" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.992007992007992" /psig="0.992007992007992" /xcortree=869 /SigmaFactorBS="tctctgtttttttatcgtgcgcaccaatTGAGAAGctaaccg cgtttttGGGCATACTAAAgcgaagaaactggaaaagttctacacattcattgaaaag g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3313781) /Source="Nicolas_upshifts" /id="U2638" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.992007992007992" /psig="0.992007992007992" /xcortree=869 /SigmaFactorBS="tctctgtttttttatcgtgcgcaccaatTGAGAAGctaaccg cgtttttGGGCATACTAAAgcgaagaaactggaaaagttctacacattcattgaaaag g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(3313807..3313813) /Source="Nicolas_upshift_promotors" /id="U2638" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.992007992007992" /psig="0.992007992007992" /xcortree=869 /SigmaFactorBS="tctctgtttttttatcgtgcgcaccaatTGAGAAGctaaccg cgtttttGGGCATACTAAAgcgaagaaactggaaaagttctacacattcattgaaaag g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" downshifts complement(3313880) /Source="Nicolas_upshifts" /id="D1744" /incds=0 /nref=20 /ntot=155 /MaxReadThrough="2.49984" /MaxDrop="4.21522" /score="11.4033831" /energy="-8" /TU="NA" /idTUdmin="U2639" /TUdmin="-11" /isTUend="TRUE" CDS complement(3313893..3314294) /gene="yvaD" /locus_tag="BSU_33560" /old_locus_tag="BSU33560" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative integral inner membrane protein" /protein_id="NP_391236.1" /db_xref="EnsemblGenomes-Gn:BSU33560" /db_xref="EnsemblGenomes-Tr:CAB15361" /db_xref="GOA:O32226" /db_xref="InterPro:IPR020348" /db_xref="SubtiList:BG14060" /db_xref="UniProtKB/Swiss-Prot:O32226" /translation="MRYMKLFFLVTDIGFILYWLSAGFSLIPESWAFKHHDHPFMIAW NWSFFPLDILISVTGLYSLYLQRVNRADWKLMALISLVLTCCSGLQALSFWTFSSDFD LVWWLFNGYLLIYPLFFIHLLLKEGRRTKQS*" gene complement(3313893..3314294) /gene="yvaD" /locus_tag="BSU_33560" /old_locus_tag="BSU33560" CDS complement(3314291..3314650) /gene="yvaE" /locus_tag="BSU_33570" /old_locus_tag="BSU33570" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 11948170, 15849754, 16850406, 19549332; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative metabolite-efflux transporter" /protein_id="NP_391237.1" /db_xref="EnsemblGenomes-Gn:BSU33570" /db_xref="EnsemblGenomes-Tr:CAB15362" /db_xref="GOA:O32227" /db_xref="InterPro:IPR000390" /db_xref="SubtiList:BG14061" /db_xref="UniProtKB/Swiss-Prot:O32227" /translation="MNWVFLCLAILFEVAGTVSMKLSSGFTKLIPSLLLIFFYGGSLF FLTLTLKSIDVSVAYAVWSGMGIVLITVVGFLFFQEHVSVMKVISIGLIIAGVVSLNL IEHVAVSEPVHKSGQYK*" gene complement(3314291..3314650) /gene="yvaE" /locus_tag="BSU_33570" /old_locus_tag="BSU33570" CDS complement(3314647..3315219) /gene="yvaF" /locus_tag="BSU_33580" /old_locus_tag="BSU33580" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative transcriptional regulator" /protein_id="NP_391238.1" /db_xref="EnsemblGenomes-Gn:BSU33580" /db_xref="EnsemblGenomes-Tr:CAB15363" /db_xref="GOA:O32228" /db_xref="InterPro:IPR001647" /db_xref="InterPro:IPR009057" /db_xref="InterPro:IPR036271" /db_xref="SubtiList:BG14062" /db_xref="UniProtKB/Swiss-Prot:O32228" /translation="MDKRILAETFRLIKQKGFSFTMNDLAAALGTSKRTLYAYYSSKD QLVEAVVEQFIAEMKQIERDIYENESLNVLEKVKQMLISLPQGMELLNMGLLNELKKY HYDAWLTLDAFIKEEWAIVLALLNECKQQKRIRNINPDLFVHMYIGSINQVYDPEYPL KHQFTTGEVLESIVDVLFNGITADEEADAT*" gene complement(3314647..3315219) /gene="yvaF" /locus_tag="BSU_33580" /old_locus_tag="BSU33580" promotor_-10 complement(3315257..3315276) /Source="Nicolas_upshift_promotors" /id="U2639" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.661338661338661" /psig=1 /xcortree=2445 /SigmaFactorBS="ccaataggagaggtttttttatataTTGTTGATttccataaa tttcTGCCGTATAATATTGGTACCgaaatagttttcttggtaccgaaagcgggggatt a" /listShort="yvaF, yvaE, yvaD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3315262) /Source="Nicolas_upshifts" /id="U2639" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.661338661338661" /psig=1 /xcortree=2445 /SigmaFactorBS="ccaataggagaggtttttttatataTTGTTGATttccataaa tttcTGCCGTATAATATTGGTACCgaaatagttttcttggtaccgaaagcgggggatt a" /listShort="yvaF, yvaE, yvaD" /GFF_Attribute="listLong" promotor_-35 complement(3315290..3315297) /Source="Nicolas_upshift_promotors" /id="U2639" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.661338661338661" /psig=1 /xcortree=2445 /SigmaFactorBS="ccaataggagaggtttttttatataTTGTTGATttccataaa tttcTGCCGTATAATATTGGTACCgaaatagttttcttggtaccgaaagcgggggatt a" /listShort="yvaF, yvaE, yvaD" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3315330..3316124) /gene="yvaG" /locus_tag="BSU_33590" /old_locus_tag="BSU33590" /EC_number="1.-.-.-" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative oxidoreductase" /protein_id="NP_391239.1" /db_xref="EnsemblGenomes-Gn:BSU33590" /db_xref="EnsemblGenomes-Tr:CAB15364" /db_xref="GOA:O32229" /db_xref="InterPro:IPR002347" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG14063" /db_xref="UniProtKB/Swiss-Prot:O32229" /translation="MKLNLQGKTALVTGSTSGIGKAIASSLAEEGAAVIINGRREEKV NQTIDELKTQHAEAVLYPAAFDLGTEEGCNELFQAYPEVDILVNNLGIFEPAEYFDIP DDEWFRFFEVNIMSGVRLTRRYLHNMIEKKEGRVIFIASEAAIMPSQEMAHYSATKTM QLSISRSLAELATGTNVTVNTVMPGSTLTEGVETMLNSLYPGENLTVQEAEARFMKEN RPTSIIQRLIRPEEIAHFVTFLSSPLSSAINGAALRADGGLVRSVF*" gene complement(3315330..3316124) /gene="yvaG" /locus_tag="BSU_33590" /old_locus_tag="BSU33590" promotor_-10 complement(3316145..3316163) /Source="Nicolas_upshift_promotors" /id="U2640" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.98101898101898" /psig="0.98101898101898" /xcortree=725 /SigmaFactorBS="atcccagctgtttcatactgattgcagagcagaTGTTTCAcc aatcagatttctGTCAATAAATAAGAGGAATcaaaaacggagggatgaataatgaagc t" /listShort="yvaG, yvaF, yvaE" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3316157) /Source="Nicolas_upshifts" /id="U2640" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.98101898101898" /psig="0.98101898101898" /xcortree=725 /SigmaFactorBS="atcccagctgtttcatactgattgcagagcagaTGTTTCAcc aatcagatttctGTCAATAAATAAGAGGAATcaaaaacggagggatgaataatgaagc t" /listShort="yvaG, yvaF, yvaE" /GFF_Attribute="listLong" promotor_-35 complement(3316178..3316184) /Source="Nicolas_upshift_promotors" /id="U2640" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.98101898101898" /psig="0.98101898101898" /xcortree=725 /SigmaFactorBS="atcccagctgtttcatactgattgcagagcagaTGTTTCAcc aatcagatttctGTCAATAAATAAGAGGAATcaaaaacggagggatgaataatgaagc t" /listShort="yvaG, yvaF, yvaE" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(3316190..3316209) /Source="Nicolas_upshift_promotors" /id="U2641" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.866133866133866" /psig="0.94005994005994" /xcortree=2724 /SigmaFactorBS="tttctccaaaccacaggcaccaaaaagtgcgTACTTCCAttt caatcccagcTGTTTCATACTGATTGCAGAgcagatgtttcaccaatcagatttctgt c" /listShort="yvaG" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3316201) /Source="Nicolas_upshifts" /id="U2641" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.866133866133866" /psig="0.94005994005994" /xcortree=2724 /SigmaFactorBS="tttctccaaaccacaggcaccaaaaagtgcgTACTTCCAttt caatcccagcTGTTTCATACTGATTGCAGAgcagatgtttcaccaatcagatttctgt c" /listShort="yvaG" /GFF_Attribute="listLong" S_feature complement(3316203..3316268) /Source="Nicolas_S_feature" /locus_tag="new_3450605_3450670_c" /HighExp="H2O2, Heat, Diami, G180, Paraq, dia15, Oxctl, BMM, G135, S1" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="Sig-, SigA" /TUshortPSig="0.47, 0.997" /TUlongSig="SigA, SigA" /TUlongPSig="0.996, 1" /label="S1285" promotor_-35 complement(3316223..3316230) /Source="Nicolas_upshift_promotors" /id="U2641" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.866133866133866" /psig="0.94005994005994" /xcortree=2724 /SigmaFactorBS="tttctccaaaccacaggcaccaaaaagtgcgTACTTCCAttt caatcccagcTGTTTCATACTGATTGCAGAgcagatgtttcaccaatcagatttctgt c" /listShort="yvaG" /GFF_Attribute="listLong" /label="promotor_-35" misc_RNA complement(3316310..3316669) /gene="ssrA" /locus_tag="BSU_misc_RNA_55" /product="transfer-messenger RNA (tmRNA, 10Sa RNA)" /experiment="publication(s) with functional evidences, PMID:11395451, 11918677, 14766921, 17369301, 18673456" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11395451, 11918677, 14766921, 17369301, 18673456" gene complement(3316310..3316669) /gene="ssrA" /locus_tag="BSU_misc_RNA_55" downshifts complement(3316313) /Source="Nicolas_upshifts" /id="D1745" /incds=0 /nref=260 /ntot=272 /MaxReadThrough="4.32959" /MaxDrop="9.81359" /score="26.7868133" /energy="-15.8" /TU="U2642,U2644" /idTUdmin="U2643" /TUdmin="-2" /isTUend="TRUE" promotor_-10 complement(3316653..3316661) /Source="Nicolas_upshift_promotors" /id="U2642" /multdbtbs="-" /comp="M2" /sig="Sig-" /pcomp="0.46953046953047" /psig="0.46953046953047" /xcortree=677 /SigmaFactorBS="atagccagtttgagtgagagcttgatattttctcccgtattt CCCTTAtaccaaggggacgtTACGGATTCgacagggatggatcgagcttgagctgcga g" /listShort="ssrA, S1285, yvaG" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3316663) /Source="Nicolas_upshifts" /id="U2642" /multdbtbs="-" /comp="M2" /sig="Sig-" /pcomp="0.46953046953047" /psig="0.46953046953047" /xcortree=677 /SigmaFactorBS="atagccagtttgagtgagagcttgatattttctcccgtattt CCCTTAtaccaaggggacgtTACGGATTCgacagggatggatcgagcttgagctgcga g" /listShort="ssrA, S1285, yvaG" /GFF_Attribute="listLong" promotor_-35 complement(3316676..3316681) /Source="Nicolas_upshift_promotors" /id="U2642" /multdbtbs="-" /comp="M2" /sig="Sig-" /pcomp="0.46953046953047" /psig="0.46953046953047" /xcortree=677 /SigmaFactorBS="atagccagtttgagtgagagcttgatattttctcccgtattt CCCTTAtaccaaggggacgtTACGGATTCgacagggatggatcgagcttgagctgcga g" /listShort="ssrA, S1285, yvaG" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(3316721..3316740) /Source="Nicolas_upshift_promotors" /id="U2643" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.563436563436563" /psig="0.999000999001" /xcortree=1661 /SigmaFactorBS="tcacgacgccattcatttgaaggatttgacaaTTGAAaagag ccgtgatCATGTTATAATAAGACTATAgccagtttgagtgagagcttgatattttctc c" /listShort="ssrA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3316729) /Source="Nicolas_upshifts" /id="U2643" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.563436563436563" /psig="0.999000999001" /xcortree=1661 /SigmaFactorBS="tcacgacgccattcatttgaaggatttgacaaTTGAAaagag ccgtgatCATGTTATAATAAGACTATAgccagtttgagtgagagcttgatattttctc c" /listShort="ssrA" /GFF_Attribute="listLong" S_feature complement(3316731..3316795) /Source="Nicolas_S_feature" /locus_tag="new_3451133_3451197_c" /HighExp="Etha, C90, dia5, dia15, Diami, T0.0H, T-0.40H, T-1.40H, LPhT, Salt" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA, SigA" /TUshortPSig="0.997, 0.996, 1" /TUlongSig="SigB, SigA" /TUlongPSig="0.999, 0.753" /label="S1286" promotor_-35 complement(3316753..3316757) /Source="Nicolas_upshift_promotors" /id="U2643" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.563436563436563" /psig="0.999000999001" /xcortree=1661 /SigmaFactorBS="tcacgacgccattcatttgaaggatttgacaaTTGAAaagag ccgtgatCATGTTATAATAAGACTATAgccagtttgagtgagagcttgatattttctc c" /listShort="ssrA" /GFF_Attribute="listLong" /label="promotor_-35" upshifts complement(3316795) /Source="Nicolas_upshifts" /id="U2644" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.701298701298701" /psig="0.997002997002997" /xcortree=1911 /SigmaFactorBS="aggcttctaaaggcatagTGCTTGATtcgaaaatcaggccTG TGCTATACTGTGTTCACGatcagatcacgacgccattcatttgaaggatttgacaatt g" /listShort="S1286, ssrA, S1285" /listLong="yvaG" promotor_-10 complement(3316796..3316815) /Source="Nicolas_upshift_promotors" /id="U2644" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.701298701298701" /psig="0.997002997002997" /xcortree=1911 /SigmaFactorBS="aggcttctaaaggcatagTGCTTGATtcgaaaatcaggccTG TGCTATACTGTGTTCACGatcagatcacgacgccattcatttgaaggatttgacaatt g" /listShort="S1286, ssrA, S1285" /listLong="yvaG" /label="promotor_-10" promotor_-35 complement(3316830..3316837) /Source="Nicolas_upshift_promotors" /id="U2644" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.701298701298701" /psig="0.997002997002997" /xcortree=1911 /SigmaFactorBS="aggcttctaaaggcatagTGCTTGATtcgaaaatcaggccTG TGCTATACTGTGTTCACGatcagatcacgacgccattcatttgaaggatttgacaatt g" /listShort="S1286, ssrA, S1285" /listLong="yvaG" /label="promotor_-35" CDS complement(3316846..3317316) /gene="smpB" /locus_tag="BSU_33600" /old_locus_tag="BSU33600" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:10947848, 11395451, 11918677, 12682299, 26735940" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10947848, 11395451, 11918677, 12682299, 26735940; Product type f: factor" /codon_start=1 /transl_table=11 /product="tmRNA-binding protein" /protein_id="NP_391240.1" /db_xref="EnsemblGenomes-Gn:BSU33600" /db_xref="EnsemblGenomes-Tr:CAB15365" /db_xref="GOA:O32230" /db_xref="InterPro:IPR000037" /db_xref="InterPro:IPR020081" /db_xref="InterPro:IPR023620" /db_xref="SubtiList:BG14064" /db_xref="UniProtKB/Swiss-Prot:O32230" /translation="MPKGSGKVLSQNKKANHDYFIEETYETGIVLQGTEIKSIRAGRV NLKDSFAKIERGEVFLHNMHVSPYEQGNRYNHDPLRTRKLLMHRKEINKLIGLTKEKG YSLVPLKLYLKNGFAKVLLGLGKGKKNYDKREDLKRKDAKREIERAFRDSQKGF*" gene complement(3316846..3317316) /gene="smpB" /locus_tag="BSU_33600" /old_locus_tag="BSU33600" promotor_no_box 3317143..3317243 /Source="Nicolas_upshift_promotors" /id="U2645" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.94005994005994" /psig="0.018981018981019" /xcortree=38 /SigmaFactorBS="cacttctccccgttcgattttggcgaaggaatccttaaggtt tacgcggccggcgcgaatcgatttgatttcggttccttgcagaacgatgcctgtttca t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_no_box" upshifts 3317203 /Source="Nicolas_upshifts" /id="U2645" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.94005994005994" /psig="0.018981018981019" /xcortree=38 /SigmaFactorBS="cacttctccccgttcgattttggcgaaggaatccttaaggtt tacgcggccggcgcgaatcgatttgatttcggttccttgcagaacgatgcctgtttca t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" downshifts 3317313 /Source="Nicolas_upshifts" /id="D1746" /incds=0 /nref=2 /ntot=105 /MaxReadThrough="0.62459" /MaxDrop="3.18501" /score="-9.3042809" /energy="-3.3" /TU="NA" /idTUdmin="U2647" /TUdmin="-1408" /isTUend="FALSE" promotor_-10 complement(3317361..3317380) /Source="Nicolas_upshift_promotors" /id="U2646" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.375624375624376" /psig="0.996003996003996" /xcortree=1853 /SigmaFactorBS="atttgctttctttcggaaacagcttttcATTGtagcggtacg tgacaTTTGGTAAAATAGAGCGTATcgcaaaaggtggacagtttttccttagagagag g" /listShort="smpB, S1286" /listLong="ssrA, S1285, yvaG" /label="promotor_-10" upshifts complement(3317367) /Source="Nicolas_upshifts" /id="U2646" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.375624375624376" /psig="0.996003996003996" /xcortree=1853 /SigmaFactorBS="atttgctttctttcggaaacagcttttcATTGtagcggtacg tgacaTTTGGTAAAATAGAGCGTATcgcaaaaggtggacagtttttccttagagagag g" /listShort="smpB, S1286" /listLong="ssrA, S1285, yvaG" S_feature complement(3317369..3317460) /Source="Nicolas_S_feature" /locus_tag="new_3451771_3451862_c" /HighExp="Etha, S8, Cold, S7, G135, G180, G150, H2O2, M9-stat, S6" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigB, SigA" /TUshortPSig="0.999, 1" /TUlongSig="SigA" /TUlongPSig="0.753" /label="S1287" promotor_-35 complement(3317396..3317399) /Source="Nicolas_upshift_promotors" /id="U2646" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.375624375624376" /psig="0.996003996003996" /xcortree=1853 /SigmaFactorBS="atttgctttctttcggaaacagcttttcATTGtagcggtacg tgacaTTTGGTAAAATAGAGCGTATcgcaaaaggtggacagtttttccttagagagag g" /listShort="smpB, S1286" /listLong="ssrA, S1285, yvaG" /label="promotor_-35" CDS complement(3317461..3319800) /gene="rnr" /locus_tag="BSU_33610" /old_locus_tag="BSU33610" /EC_number="3.1.13.1" /function="16.3: Control" /function="16.11: Scavenge (Catabolism)" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:12399495, 15805522, 15983136, 19215769, 22333191" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12399495, 15805522, 15983136, 19215769, 22333191; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="ribonuclease R" /protein_id="NP_391241.1" /db_xref="EnsemblGenomes-Gn:BSU33610" /db_xref="EnsemblGenomes-Tr:CAB15366" /db_xref="GOA:O32231" /db_xref="InterPro:IPR003029" /db_xref="InterPro:IPR004476" /db_xref="InterPro:IPR011129" /db_xref="InterPro:IPR011805" /db_xref="InterPro:IPR012340" /db_xref="InterPro:IPR013223" /db_xref="InterPro:IPR022966" /db_xref="InterPro:IPR022967" /db_xref="InterPro:IPR036388" /db_xref="SubtiList:BG14065" /db_xref="UniProtKB/Swiss-Prot:O32231" /translation="MEKEAFMEKLLSFMKEEAYKPLTVQELEEMLNITEAEEFKELVK ALVALEEKGLIVRTRSDRYGIPEKMNLIKGKISAHAKGFAFLLPEDTSLSDVFIPPNE LNTAMNGDIVMVRLNSQSSGSRQEGTVIRILERAIQRVVGTYTETRNFGFVIPDDKKI TSDIFIPKNGKNGAAEGHKVVVKLTSYPEGRMNAEGEVETILGHKNDPGIDILSVIHK HGLPGEFPADAMEQASSTPDTIDEKDLKDRRDLRDQVIVTIDGADAKDLDDAVTVTKL DDGSYKLGVHIADVSHYVTENSPIDKEALERGTSVYLVDRVIPMIPHRLSNGICSLNP KVDRLTLSCEMTINSQGQVTEHEIFQSVIKTTERMTYSDVNKILVDDDEELKQKYEPL VPMFKDMERLAQILRDKRMDRGAVDFDFKEAKVLVDDEGAVKDVVIRERSVAEKLIEE FMLVANETVAEHFHWMNVPFIYRIHEEPNAEKLQKFLEFVTTFGYVVKGTAGNIHPRA LQSILDAVRDRPEETVISTVMLRSMKQAKYDPQSLGHFGLSTEFYTHFTSPIRRYPDL IVHRLIRTYLINGKVDEATQEKWAERLPDIAEHTSSMERRAVDAERETDDLKKAEYML DKIGEEFDGMISSVTNFGMFVELPNTIEGLVHVSFMTDDYYRFDEQHFAMIGERTGNV FRIGDEITVKVVDVNKDERNIDFEIVGMKGTPRRPRELDSSRSRKRGKPARKRVQSTN TPVSPAPSEEKGEWFTKPKKKKKKRGFQNAPKQKRKKKK*" gene complement(3317461..3319800) /gene="rnr" /locus_tag="BSU_33610" /old_locus_tag="BSU33610" promotor_-35 3318561..3318564 /Source="Nicolas_upshift_promotors" /id="U2647" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.988011988011988" /psig="0.000999000999001" /xcortree=49 /SigmaFactorBS="ctttgcttctttgaaatcaaagtcaacggcgcCGCGgtccat ccgcttatcGCGCagaatttgagccagacgctccatgtctttgaacatcggaacaaga g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3318580..3318583 /Source="Nicolas_upshift_promotors" /id="U2647" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.988011988011988" /psig="0.000999000999001" /xcortree=49 /SigmaFactorBS="ctttgcttctttgaaatcaaagtcaacggcgcCGCGgtccat ccgcttatcGCGCagaatttgagccagacgctccatgtctttgaacatcggaacaaga g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3318589 /Source="Nicolas_upshifts" /id="U2647" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.988011988011988" /psig="0.000999000999001" /xcortree=49 /SigmaFactorBS="ctttgcttctttgaaatcaaagtcaacggcgcCGCGgtccat ccgcttatcGCGCagaatttgagccagacgctccatgtctttgaacatcggaacaaga g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" CDS complement(3319819..3320559) /gene="estA" /locus_tag="BSU_33620" /old_locus_tag="BSU33620" /EC_number="3.1.1.1" /function="16.8: Protect" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 1369099, 17369301; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="carboxylesterase" /protein_id="NP_391242.2" /db_xref="EnsemblGenomes-Gn:BSU33620" /db_xref="EnsemblGenomes-Tr:CAB15367" /db_xref="GOA:O32232" /db_xref="InterPro:IPR012354" /db_xref="InterPro:IPR022742" /db_xref="InterPro:IPR029058" /db_xref="SubtiList:BG14066" /db_xref="UniProtKB/Swiss-Prot:O32232" /translation="MKVVTPKPFTFKGGDKAVLLLHGFTGNTADVRMLGRYLNERGYT CHAPQYEGHGVPPEELVHTGPEDWWKNVMDGYEYLKSEGYESIAACGLSLGGVFSLKL GYTVPIKGIVPMCAPMHIKSEEVMYQGVLSYARNYKKFEGKSPEQIEEEMKEFEKTPM NTLKALQDLIADVRNNVDMIYSPTFVVQARHDHMINTESANIIYNEVETDDKQLKWYE ESGHVITLDKERDLVHQDVYEFLEKLDW*" gene complement(3319819..3320559) /gene="estA" /locus_tag="BSU_33620" /old_locus_tag="BSU33620" promotor_-10 complement(3320215..3320233) /Source="Nicolas_upshift_promotors" /id="U2648" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=745 /SigmaFactorBS="actgtcgcttggcggggttttttcgctgaaattGGGTTACac tgtacccataaaGGGAATTGTCCCAATGTGCgcaccgatgcatattaagagtgaagag g" /listShort="rnr, S1287, smpB" /listLong="S1286, ssrA" /label="promotor_-10" upshifts complement(3320227) /Source="Nicolas_upshifts" /id="U2648" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=745 /SigmaFactorBS="actgtcgcttggcggggttttttcgctgaaattGGGTTACac tgtacccataaaGGGAATTGTCCCAATGTGCgcaccgatgcatattaagagtgaagag g" /listShort="rnr, S1287, smpB" /listLong="S1286, ssrA" promotor_-35 complement(3320248..3320254) /Source="Nicolas_upshift_promotors" /id="U2648" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=745 /SigmaFactorBS="actgtcgcttggcggggttttttcgctgaaattGGGTTACac tgtacccataaaGGGAATTGTCCCAATGTGCgcaccgatgcatattaagagtgaagag g" /listShort="rnr, S1287, smpB" /listLong="S1286, ssrA" /label="promotor_-35" misc_feature complement(3320587..3320605) /Source="Nicolas_upshift_promotors" /id="U2649" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.376623376623377" /psig="0.753246753246753" /xcortree=634 /SigmaFactorBS="gtcaggcctttttcacgtttctggatgatattcaaaacgttt ttttctgattaaacTGTGGAAAACTAAAATGATcgtgcagatagaaagggagacatga g" /listShort="yvaK, rnr" /listLong="S1287, smpB, S1286, ssrA" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(3320601) /Source="Nicolas_upshifts" /id="U2649" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.376623376623377" /psig="0.753246753246753" /xcortree=634 /SigmaFactorBS="gtcaggcctttttcacgtttctggatgatattcaaaacgttt ttttctgattaaacTGTGGAAAACTAAAATGATcgtgcagatagaaagggagacatga g" /listShort="yvaK, rnr" /listLong="S1287, smpB, S1286, ssrA" downshifts complement(3320689) /Source="Nicolas_upshifts" /id="D1747" /incds=0 /nref=30 /ntot=212 /MaxReadThrough="6.16751" /MaxDrop="5.2246" /score="-4.14736839" /energy="-9.1" /TU="U2650" /idTUdmin="U2649" /TUdmin="-3234" /isTUend="FALSE" CDS complement(3320691..3320921) /gene="secG" /locus_tag="BSU_33630" /old_locus_tag="BSU33630" /function="16.2: Construct biomass (Anabolism)" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:10074070, 10644701, 16243836" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10074070, 10644701, 16243836; Product type f: factor" /codon_start=1 /transl_table=11 /product="preprotein translocase subunit" /protein_id="NP_391243.1" /db_xref="EnsemblGenomes-Gn:BSU33630" /db_xref="EnsemblGenomes-Tr:CAB15368" /db_xref="GOA:O32233" /db_xref="InterPro:IPR004692" /db_xref="SubtiList:BG14067" /db_xref="UniProtKB/Swiss-Prot:O32233" /translation="MHAVLITLLVIVSIALIIVVLLQSSKSAGLSGAISGGAEQLFGK QKARGLDLILHRITVVLAVLFFVLTIALAYIL*" gene complement(3320691..3320921) /gene="secG" /locus_tag="BSU_33630" /old_locus_tag="BSU33630" promotor_-10 complement(3320951..3320970) /Source="Nicolas_upshift_promotors" /id="U2650" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.903096903096903" /psig=1 /xcortree=2177 /SigmaFactorBS="accaagataaaacgtcttatccggccttttggcgtctgatac agCGTGacatgccaacccttTTCATGTAAAATAGAAGTAAtgtagccagtgagtctgg a" /listShort="secG, yvaK, rnr, S1287, smpB, S1286" /listLong="ssrA, S1285, yvaG" /label="promotor_-10" upshifts complement(3320972) /Source="Nicolas_upshifts" /id="U2650" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.903096903096903" /psig=1 /xcortree=2177 /SigmaFactorBS="accaagataaaacgtcttatccggccttttggcgtctgatac agCGTGacatgccaacccttTTCATGTAAAATAGAAGTAAtgtagccagtgagtctgg a" /listShort="secG, yvaK, rnr, S1287, smpB, S1286" /listLong="ssrA, S1285, yvaG" promotor_-35 complement(3320985..3320988) /Source="Nicolas_upshift_promotors" /id="U2650" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.903096903096903" /psig=1 /xcortree=2177 /SigmaFactorBS="accaagataaaacgtcttatccggccttttggcgtctgatac agCGTGacatgccaacccttTTCATGTAAAATAGAAGTAAtgtagccagtgagtctgg a" /listShort="secG, yvaK, rnr, S1287, smpB, S1286" /listLong="ssrA, S1285, yvaG" /label="promotor_-35" promotor_-35 3321010..3321016 /Source="Nicolas_upshift_promotors" /id="U2651" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=928 /SigmaFactorBS="aagggttggcatgtcacgctgtatcagacgccaaaaggcCGG ATAAgacgttttatcttGGTTACCCTATTcatatgaaaaggtcaaaggagaaaagcga t" /listShort="yvaM" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3321030..3321041 /Source="Nicolas_upshift_promotors" /id="U2651" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=928 /SigmaFactorBS="aagggttggcatgtcacgctgtatcagacgccaaaaggcCGG ATAAgacgttttatcttGGTTACCCTATTcatatgaaaaggtcaaaggagaaaagcga t" /listShort="yvaM" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3321031 /Source="Nicolas_upshifts" /id="U2651" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=928 /SigmaFactorBS="aagggttggcatgtcacgctgtatcagacgccaaaaggcCGG ATAAgacgttttatcttGGTTACCCTATTcatatgaaaaggtcaaaggagaaaagcga t" /listShort="yvaM" /GFF_Attribute="listLong" CDS 3321070..3321840 /gene="yvaM" /locus_tag="BSU_33640" /old_locus_tag="BSU33640" /EC_number="3.-.-.-" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative hydrolase" /protein_id="NP_391244.1" /db_xref="EnsemblGenomes-Gn:BSU33640" /db_xref="EnsemblGenomes-Tr:CAB15369" /db_xref="GOA:O32234" /db_xref="InterPro:IPR000073" /db_xref="InterPro:IPR029058" /db_xref="SubtiList:BG14068" /db_xref="UniProtKB/Swiss-Prot:O32234" /translation="MPLISIDSRKHLFYEEYGQGIPIIFIHPPGMGRKVFYYQRLLSK HFRVIFPDLSGHGDSDHIDQPASISYYANEIAQFMDALHIDKAVLFGYSAGGLIAQHI GFTRPDKVSHLILSGAYPAVHNVIGQKLHKLGMYLLEKNPGLLMKILAGSHTKDRQLR SILTDHMKKADQAHWHQYYLDSLGYNCIEQLPRLEMPMLFMYGGLRDWTFTNAGYYRR SCRHAEFFRLEYQGHQLPTKQWKTCNELVTGFVLTHHS*" gene 3321070..3321840 /gene="yvaM" /locus_tag="BSU_33640" /old_locus_tag="BSU33640" promotor_-35 3321092..3321100 /Source="Nicolas_upshift_promotors" /id="U2652" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.99100899100899" /psig="0.99100899100899" /xcortree=538 /SigmaFactorBS="cagcatagacaGCAGGAAACatcttttttaTGAAGAATATGG ACAGGGAatccctatcatttttatccacccgccgggcatgggacgaaaggttttttat t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3321111..3321129 /Source="Nicolas_upshift_promotors" /id="U2652" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.99100899100899" /psig="0.99100899100899" /xcortree=538 /SigmaFactorBS="cagcatagacaGCAGGAAACatcttttttaTGAAGAATATGG ACAGGGAatccctatcatttttatccacccgccgggcatgggacgaaaggttttttat t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3321141 /Source="Nicolas_upshifts" /id="U2652" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.99100899100899" /psig="0.99100899100899" /xcortree=538 /SigmaFactorBS="cagcatagacaGCAGGAAACatcttttttaTGAAGAATATGG ACAGGGAatccctatcatttttatccacccgccgggcatgggacgaaaggttttttat t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" CDS complement(3321880..3322113) /gene="yvzC" /locus_tag="BSU_33650" /old_locus_tag="BSU33650" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative phage-like transcriptional regulator" /protein_id="NP_391245.1" /db_xref="EnsemblGenomes-Gn:BSU33650" /db_xref="EnsemblGenomes-Tr:CAB15370" /db_xref="GOA:O32235" /db_xref="InterPro:IPR001387" /db_xref="InterPro:IPR010982" /db_xref="SubtiList:BG14159" /db_xref="UniProtKB/Swiss-Prot:O32235" /translation="MPVEKIQIRRDYVLQYMVNNDYSLNQLALEIGVSPATLSRVLNG ERRPGQLVIGKMLHYFNLKFEDLFYYDFVDKSQ*" gene complement(3321880..3322113) /gene="yvzC" /locus_tag="BSU_33650" /old_locus_tag="BSU33650" promotor_-35 3322204..3322211 /Source="Nicolas_upshift_promotors" /id="U2653" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.5994005994006" /psig="0.985014985014985" /xcortree=2531 /SigmaFactorBS="attacggcttatgttaacttttgtcaatacatttccagtcta cctATTCCCTTtagtcaataaaCATACTAAAATATGAGTAACagtgagggacggggtg a" /listShort="rghRA, rghRB, yvaP" /listLong="S1288, yvaQ" /label="promotor_-35" upshifts 3322219 /Source="Nicolas_upshifts" /id="U2653" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.5994005994006" /psig="0.985014985014985" /xcortree=2531 /SigmaFactorBS="attacggcttatgttaacttttgtcaatacatttccagtcta cctATTCCCTTtagtcaataaaCATACTAAAATATGAGTAACagtgagggacggggtg a" /listShort="rghRA, rghRB, yvaP" /listLong="S1288, yvaQ" promotor_-10 3322223..3322242 /Source="Nicolas_upshift_promotors" /id="U2653" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.5994005994006" /psig="0.985014985014985" /xcortree=2531 /SigmaFactorBS="attacggcttatgttaacttttgtcaatacatttccagtcta cctATTCCCTTtagtcaataaaCATACTAAAATATGAGTAACagtgagggacggggtg a" /listShort="rghRA, rghRB, yvaP" /listLong="S1288, yvaQ" /label="promotor_-10" CDS 3322265..3322672 /gene="rghRA" /locus_tag="BSU_33660" /old_locus_tag="BSU33660" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:16553878, 17227471" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16553878, 17227471; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional repressor" /protein_id="NP_391246.1" /db_xref="EnsemblGenomes-Gn:BSU33660" /db_xref="EnsemblGenomes-Tr:CAB15371" /db_xref="GOA:O32236" /db_xref="InterPro:IPR001387" /db_xref="InterPro:IPR010982" /db_xref="InterPro:IPR016759" /db_xref="SubtiList:BG14069" /db_xref="UniProtKB/Swiss-Prot:O32236" /translation="MESFGEQLRALREERKLTVNQLATYSGVSAAGISRIENGKRGVP KPATIKKLAEALKIPYEGLMYKAGYIEEVHEARAPYETKCKLLEKAEAYDLKNLALLE NEKWQYLNKEDLLMLDHYFSFISDEAKKRSADD*" gene 3322265..3322672 /gene="rghRA" /locus_tag="BSU_33660" /old_locus_tag="BSU33660" CDS 3322702..3323121 /gene="rghRB" /locus_tag="BSU_33670" /old_locus_tag="BSU33670" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 17227471; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative phage-like transcriptional repressor" /protein_id="NP_391247.1" /db_xref="EnsemblGenomes-Gn:BSU33670" /db_xref="EnsemblGenomes-Tr:CAB15372" /db_xref="GOA:O32237" /db_xref="InterPro:IPR001387" /db_xref="InterPro:IPR010982" /db_xref="InterPro:IPR016759" /db_xref="SubtiList:BG14070" /db_xref="UniProtKB/Swiss-Prot:O32237" /translation="MSPFGQQLRELRRARKLTVNQLAVYSGISSATISKIENGKRGTP KPATIKKLAAVLKVPYENLMAAAGHIQAFPEEIREASEGYQSVYEIYQTAVTRGAEHL PIFNSQKWEHLSKQDIENLSKYFDFLSSEAKKRASSS*" gene 3322702..3323121 /gene="rghRB" /locus_tag="BSU_33670" /old_locus_tag="BSU33670" promotor_-35 3323159..3323166 /Source="Nicolas_upshift_promotors" /id="U2654" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.929070929070929" /psig=1 /xcortree=2041 /SigmaFactorBS="tgtttctctttctatattttatcaatcacgctTGCATGCCct ccctcgttattTGCGTTATAATAGTGACAGAcgaggtgaaaagtatgaaccaatcaga a" /listShort="yvaP, S1288, yvaQ" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3323180..3323199 /Source="Nicolas_upshift_promotors" /id="U2654" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.929070929070929" /psig=1 /xcortree=2041 /SigmaFactorBS="tgtttctctttctatattttatcaatcacgctTGCATGCCct ccctcgttattTGCGTTATAATAGTGACAGAcgaggtgaaaagtatgaaccaatcaga a" /listShort="yvaP, S1288, yvaQ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3323187 /Source="Nicolas_upshifts" /id="U2654" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.929070929070929" /psig=1 /xcortree=2041 /SigmaFactorBS="tgtttctctttctatattttatcaatcacgctTGCATGCCct ccctcgttattTGCGTTATAATAGTGACAGAcgaggtgaaaagtatgaaccaatcaga a" /listShort="yvaP, S1288, yvaQ" /GFF_Attribute="listLong" CDS 3323213..3323539 /gene="catR" /locus_tag="BSU_33680" /old_locus_tag="BSU33680" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:20639328" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 20639328; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator of catechol dioxygenase" /protein_id="NP_391248.2" /db_xref="EnsemblGenomes-Gn:BSU33680" /db_xref="EnsemblGenomes-Tr:CAB15373" /db_xref="GOA:O32238" /db_xref="InterPro:IPR002577" /db_xref="InterPro:IPR011991" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG14071" /db_xref="UniProtKB/Swiss-Prot:O32238" /translation="MNQSEMCPRFEKAVDILSKRWVALIVFQLLNGSQRFSEIEAALP NLSGRVLSERLKELELEGVVKRDVIPETPVRIEYSLTDKGKALAPILGEISKWATEWI DPSFLD*" gene 3323213..3323539 /gene="catR" /locus_tag="BSU_33680" /old_locus_tag="BSU33680" S_feature 3323540..3323624 /Source="Nicolas_S_feature" /locus_tag="new_3457942_3458026" /HighExp="Cold, H2O2, Diami, LBGstat, LPhT, dia15, G180, Paraq, Etha, Oxctl" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="SigA" /TUlongPSig="0.985" /label="S1288" promotor_-35 3323595..3323602 /Source="Nicolas_upshift_promotors" /id="U2655" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2826 /SigmaFactorBS="acgagaaaagaaccgttttttattttccaGGTGAAAAaaaga tatctcaGCCGATATATAGTACATCCacacattacgtttttaaaggagaccactatat g" /listShort="yvaQ" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3323615..3323633 /Source="Nicolas_upshift_promotors" /id="U2655" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2826 /SigmaFactorBS="acgagaaaagaaccgttttttattttccaGGTGAAAAaaaga tatctcaGCCGATATATAGTACATCCacacattacgtttttaaaggagaccactatat g" /listShort="yvaQ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3323626 /Source="Nicolas_upshifts" /id="U2655" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2826 /SigmaFactorBS="acgagaaaagaaccgttttttattttccaGGTGAAAAaaaga tatctcaGCCGATATATAGTACATCCacacattacgtttttaaaggagaccactatat g" /listShort="yvaQ" /GFF_Attribute="listLong" CDS 3323664..3325364 /gene="yvaQ" /locus_tag="BSU_33690" /old_locus_tag="BSU33690" /function="16.3: Control" /function="16.12: Sense" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 8188684, 11872722, 27899502; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative methyl-accepting transducer" /protein_id="NP_391249.1" /db_xref="EnsemblGenomes-Gn:BSU33690" /db_xref="EnsemblGenomes-Tr:CAB15374" /db_xref="GOA:O32239" /db_xref="InterPro:IPR003660" /db_xref="InterPro:IPR004089" /db_xref="InterPro:IPR004090" /db_xref="InterPro:IPR024478" /db_xref="InterPro:IPR035440" /db_xref="SubtiList:BG14072" /db_xref="UniProtKB/Swiss-Prot:O32239" /translation="MRLTISRKFSLVFLTLILINLLVGGIGVLNMQHIIQKTDEINTK WIDGIKGITSINYVTEHLSSKEKDFLIYTDKSKMDTLDQEMNQIMEDINQKLDNYEKT ISTDKEQKLFEQLQTKVNTYMDIHAQIIESGRTNDMDKARGLLVQTEASFEDMKKTIT QLVDLNQEGSNTAVKETKAVYHKGLIYTALLVAASILISIFIWLYITRNIVKPIIRMK ESANHIAEGDLSNDMEALNSKDELGDLNEALQKMVGNLRDIVGYSKDISSRVLSSSQV LATATNETRSGSKHITETMNEMAEGSEQQAQDAVTIAESMNEFTESIDKAYNHGITIS DTSQNVLELAVSGNENMATSLQQMKTIHHIVEEAVHKVRSLEQHSQDINKLVQVINGI AEQTNLLSLNAAIEAARAGESGKGFAVVAEEVRKLADGVSDSVQDITRIVNGTQQEIH TVITYLESSFTEVEKGTENLTDTGQAMQHIKQSVTHVADSIKEVTDGLKQLTNQSITI NQSIENIASVSEESAAGIEETFSITEQSAHSMDQVLLNAEELEQLANELNEKMGQFTI *" gene 3323664..3325364 /gene="yvaQ" /locus_tag="BSU_33690" /old_locus_tag="BSU33690" S_feature complement(3324380..3325373) /Source="Nicolas_S_feature" /locus_tag="new_3458782_3459775_c" /HighExp="S6, S5, S7, C30, S8, S4, S3, LoTm, BT, B36" /AntisenseName="yvaQ" /AntisenseCor="-0.38660715434937498" /AntisenseRegPval="-10.3" /CDS_PredictionProba="NA" /TUshortSig="NA" /TUshortPSig="NA" /TUlongSig="NA" /TUlongPSig="NA" /label="S1289" downshifts 3325342 /Source="Nicolas_upshifts" /id="D1748" /incds=0 /nref=30 /ntot=152 /MaxReadThrough="1.43789" /MaxDrop="3.86744" /score="26.1532813" /energy="-12.2" /TU="NA" /idTUdmin="U2655" /TUdmin=0 /isTUend="TRUE" CDS complement(3325404..3326084) /gene="opuBD" /locus_tag="BSU_33700" /old_locus_tag="BSU33700" /function="16.1: Circulate" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:9925583, 10216873, 15849754, 16850406" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9925583, 10216873, 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="choline ABC transporter (permease)" /protein_id="NP_391250.1" /db_xref="EnsemblGenomes-Gn:BSU33700" /db_xref="EnsemblGenomes-Tr:CAB15375" /db_xref="GOA:P39775" /db_xref="InterPro:IPR000515" /db_xref="InterPro:IPR035906" /db_xref="SubtiList:BG12636" /db_xref="UniProtKB/Swiss-Prot:P39775" /translation="MNVLEQLMTYYAQNGSYVMDEFGRHFLMSAYGVLFAAVVGVPAG ILIAHFRRLSAWVFAVTNVIQTIPALAMLAVLMLVMGLGANTVILSLFLYSLLPIIRN TYTGIISIEHAYLESGKAMGMTKFQVLRMVELPLALSVIMAGLRTALVIAIGITAIGT FVGAGGLGDMIVRGSNATNGTAIILAGAIPTAVMAVGADLLMAWLERALSPVKKKRTG AKHVQSAA*" gene complement(3325404..3326084) /gene="opuBD" /locus_tag="BSU_33700" /old_locus_tag="BSU33700" downshifts complement(3325418) /Source="Nicolas_upshifts" /id="D1749" /incds=0 /nref=119 /ntot=171 /MaxReadThrough="3.12805" /MaxDrop="5.39624" /score="35.0134287" /energy="-12.2" /TU="NA" /idTUdmin="U2657" /TUdmin=0 /isTUend="TRUE" promotor_-35 3325778..3325784 /Source="Nicolas_upshift_promotors" /id="U2656" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=210 /SigmaFactorBS="taggcatgttcaatactgataatgcctgtgtacgTGTTTCGa ataatcggcagcaGGGAATACAGAAATAATGAtagaatcacggtatttgcgccgagcc c" /listShort="S1290" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3325799..3325817 /Source="Nicolas_upshift_promotors" /id="U2656" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=210 /SigmaFactorBS="taggcatgttcaatactgataatgcctgtgtacgTGTTTCGa ataatcggcagcaGGGAATACAGAAATAATGAtagaatcacggtatttgcgccgagcc c" /listShort="S1290" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 3325804..3328555 /Source="Nicolas_S_feature" /locus_tag="new_3460206_3462957" /HighExp="Sw, M9-stat, B60, Salt, LoTm, T0.30H, BC, Gly, B36, T1.0H" /AntisenseName="opuBC" /AntisenseCor="-0.13125567572652899" /AntisenseRegPval="-1.5" /CDS_PredictionProba="NA" /TUshortSig="SigB" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1290" upshifts 3325804 /Source="Nicolas_upshifts" /id="U2656" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=210 /SigmaFactorBS="taggcatgttcaatactgataatgcctgtgtacgTGTTTCGa ataatcggcagcaGGGAATACAGAAATAATGAtagaatcacggtatttgcgccgagcc c" /listShort="S1290" /GFF_Attribute="listLong" CDS complement(3326101..3327021) /gene="opuBC" /locus_tag="BSU_33710" /old_locus_tag="BSU33710" /function="16.1: Circulate" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:9925583, 10216873" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9925583, 10216873; Product type t: transporter" /codon_start=1 /transl_table=11 /product="choline ABC transporter (choline-binding lipoprotein)" /protein_id="NP_391251.1" /db_xref="EnsemblGenomes-Gn:BSU33710" /db_xref="EnsemblGenomes-Tr:CAB15376" /db_xref="GOA:Q45462" /db_xref="InterPro:IPR007210" /db_xref="PDB:3R6U" /db_xref="SubtiList:BG12635" /db_xref="UniProtKB/Swiss-Prot:Q45462" /translation="MKRKYLKLMIGLALAATLTLSGCSLPGLSAAADQTIKIGAQSMS ESEIIASMLGQLIEHHTDLKTTTIKNLGSNAVQQQALMNGEIDIAATRYTGDALTGTL RMEPEKDPDKALALTQREFKKRYDLKWYDSYGFDNTYAFTVSKELADQYHLETVSDVK KWAPQLKLGVDNYWMKLKGNGYQDFTKTYGMTFGGTYPMQIGLVYDAVKSGKMDIVLA YSTDGRIKSYGLKMLKDDKQFFPPYDCSPVVPEKVLKEHPELEGIIKKMLGKIDTATM QELNYEVDGNLKEPSVVAKEYLEKHRYFES*" gene complement(3326101..3327021) /gene="opuBC" /locus_tag="BSU_33710" /old_locus_tag="BSU33710" CDS complement(3327033..3327686) /gene="opuBB" /locus_tag="BSU_33720" /old_locus_tag="BSU33720" /function="16.1: Circulate" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:9925583, 10216873, 15849754, 16850406" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9925583, 10216873, 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="choline ABC transporter (permease)" /protein_id="NP_391252.1" /db_xref="EnsemblGenomes-Gn:BSU33720" /db_xref="EnsemblGenomes-Tr:CAB15377" /db_xref="GOA:Q45461" /db_xref="InterPro:IPR000515" /db_xref="InterPro:IPR035906" /db_xref="SubtiList:BG12634" /db_xref="UniProtKB/Swiss-Prot:Q45461" /translation="MHHIVQFLQTNGGELLYKTYEHITISLIAVILGVLVAVPLGVVL TRMKKGAGTIIGIVNIIQTLPSLAILAFFIPLLGVGKVPAIVALFFYSVLPILRNTYT GIRGVNKNLLESGKGIGMTPAEQVRLVELPLAAPVIMAGIRTSTIYLIGWATLASFIG GGGLGDYIFIGLNLYQPEYIIGGAVPVTILAIVIDYVLAVAERKLTPAGMQRLKELS* " gene complement(3327033..3327686) /gene="opuBB" /locus_tag="BSU_33720" /old_locus_tag="BSU33720" CDS complement(3327703..3328848) /gene="opuBA" /locus_tag="BSU_33730" /old_locus_tag="BSU33730" /function="16.1: Circulate" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:9925583, 10216873, 18321243, 21658392" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9925583, 10216873, 18321243, 21658392; Product type t: transporter" /codon_start=1 /transl_table=11 /product="choline ABC transporter (ATP-binding protein)" /protein_id="NP_391253.1" /db_xref="EnsemblGenomes-Gn:BSU33730" /db_xref="EnsemblGenomes-Tr:CAB15378" /db_xref="GOA:Q45460" /db_xref="InterPro:IPR000644" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR005892" /db_xref="InterPro:IPR017871" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG12633" /db_xref="UniProtKB/Swiss-Prot:Q45460" /translation="MLTLENVSKTYKGGKKAVNNVNLKIAKGEFICFIGPSGCGKTTT MKMINRLIEPSAGKIFIDGENIMDQDPVELRRKIGYVIQQIGLFPHMTIQQNISLVPK LLKWPEQQRKERARELLKLVDMGPEYVDRYPHELSGGQQQRIGVLRALAAEPPLILMD EPFGALDPITRDSLQEEFKKLQKTLHKTIVFVTHDMDEAIKLADRIVILKAGEIVQVG TPDDILRNPADEFVEEFIGKERLIQSSSPDVERVDQIMNTQPVTITADKTLSEAIQLM RQERVDSLLVVNDERVLQGYVDVEIIDQCRKKANLVSEVLHEDIYTVLGGTLLRDTVR KILKRGVKYVPVVDEDRRLIGIVTRASLVDIVYDSLWGEEKQLAALS*" gene complement(3327703..3328848) /gene="opuBA" /locus_tag="BSU_33730" /old_locus_tag="BSU33730" S_feature complement(3328849..3328916) /Source="Nicolas_S_feature" /locus_tag="new_3463251_3463318_c" /HighExp="T5.0H, T3.30H, T3.0H, T-5.40H, T4.0H, T-0.40H, T-1.40H, T2.30H, T-3.40H, T-2.40H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1291" upshifts complement(3328916) /Source="Nicolas_upshifts" /id="U2657" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.954045954045954" /psig=1 /xcortree=3047 /SigmaFactorBS="aataatatgaacaaattgtaaaCTTTttattttataaactTT ATTCTATAATGGGAAGCAttcaattgtctgaaaaattaaatttaaactgaacaaattg a" /listShort="S1291, opuBA, opuBB, opuBC, opuBD" /GFF_Attribute="listLong" promotor_-10 complement(3328917..3328936) /Source="Nicolas_upshift_promotors" /id="U2657" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.954045954045954" /psig=1 /xcortree=3047 /SigmaFactorBS="aataatatgaacaaattgtaaaCTTTttattttataaactTT ATTCTATAATGGGAAGCAttcaattgtctgaaaaattaaatttaaactgaacaaattg a" /listShort="S1291, opuBA, opuBB, opuBC, opuBD" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 3328947..3328951 /Source="Nicolas_upshift_promotors" /id="U2658" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.804195804195804" /psig="0.804195804195804" /xcortree=1202 /SigmaFactorBS="ttgaatgcttcccattatagaataaagtttataaaATAAAaa gtttacaatttgtTCATATTATTTATAAAGTAtgtgtaaacgctgatttacccgcatt g" /listShort="yvaV" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 complement(3328951..3328954) /Source="Nicolas_upshift_promotors" /id="U2657" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.954045954045954" /psig=1 /xcortree=3047 /SigmaFactorBS="aataatatgaacaaattgtaaaCTTTttattttataaactTT ATTCTATAATGGGAAGCAttcaattgtctgaaaaattaaatttaaactgaacaaattg a" /listShort="S1291, opuBA, opuBB, opuBC, opuBD" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3328967..3328985 /Source="Nicolas_upshift_promotors" /id="U2658" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.804195804195804" /psig="0.804195804195804" /xcortree=1202 /SigmaFactorBS="ttgaatgcttcccattatagaataaagtttataaaATAAAaa gtttacaatttgtTCATATTATTTATAAAGTAtgtgtaaacgctgatttacccgcatt g" /listShort="yvaV" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3328972 /Source="Nicolas_upshifts" /id="U2658" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.804195804195804" /psig="0.804195804195804" /xcortree=1202 /SigmaFactorBS="ttgaatgcttcccattatagaataaagtttataaaATAAAaa gtttacaatttgtTCATATTATTTATAAAGTAtgtgtaaacgctgatttacccgcatt g" /listShort="yvaV" /GFF_Attribute="listLong" promotor_-35 3329067..3329071 /Source="Nicolas_upshift_promotors" /id="U2659" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.955044955044955" /psig=1 /xcortree=2455 /SigmaFactorBS="tattgctccaatttcctgccaaattctcttttgacagCATTT tcgccgtatcaaaaaTGTGGTATATTGACATCGGAattgttagctgaaaggatgaaac c" /listShort="yvaV" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3329087..3329106 /Source="Nicolas_upshift_promotors" /id="U2659" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.955044955044955" /psig=1 /xcortree=2455 /SigmaFactorBS="tattgctccaatttcctgccaaattctcttttgacagCATTT tcgccgtatcaaaaaTGTGGTATATTGACATCGGAattgttagctgaaaggatgaaac c" /listShort="yvaV" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3329090 /Source="Nicolas_upshifts" /id="U2659" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.955044955044955" /psig=1 /xcortree=2455 /SigmaFactorBS="tattgctccaatttcctgccaaattctcttttgacagCATTT tcgccgtatcaaaaaTGTGGTATATTGACATCGGAattgttagctgaaaggatgaaac c" /listShort="yvaV" /GFF_Attribute="listLong" CDS 3329132..3329665 /gene="yvaV" /locus_tag="BSU_33740" /old_locus_tag="BSU33740" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative transcriptional regulator (controlling choline uptake)" /protein_id="NP_391254.2" /db_xref="EnsemblGenomes-Gn:BSU33740" /db_xref="EnsemblGenomes-Tr:CAB15379" /db_xref="GOA:C0SPB8" /db_xref="InterPro:IPR026282" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG14073" /db_xref="UniProtKB/Swiss-Prot:C0SPB8" /translation="MEKDPLTIIEQAEDHFIERIAENMHAFGMPSTVGRVLGIIYMNR KPMTLTELSEATGMSKTRMSQVVREMLDANIAEKVFEKGVRKDLYEVEQDYYQTFITL FSATWSKVVSKNKMMHKKLNRELLSVLDEELTPEAEEKVNELLKELKEWLDYYNWLSR LIEFFESEDIFKYVPKP*" gene 3329132..3329665 /gene="yvaV" /locus_tag="BSU_33740" /old_locus_tag="BSU33740" S_feature complement(3329332..3329851) /Source="Nicolas_S_feature" /locus_tag="new_3463734_3464253_c" /HighExp="S8, Cold, C30, GM 25, GM 60, BC, T-4.40H, M/G, GM-0.1, MG 120" /AntisenseName="yvaV" /AntisenseCor="-7.6123637680436104E-2" /AntisenseRegPval="-0.7" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA, SigA" /TUshortPSig="0.503, 1, 0.758" /TUlongSig="NA" /TUlongPSig="NA" /label="S1292" downshifts 3329654 /Source="Nicolas_upshifts" /id="D1750" /incds=0 /nref=51 /ntot=161 /MaxReadThrough="2.68472" /MaxDrop="4.69377" /score="-3.5823381" /energy="-8.6" /TU="NA" /idTUdmin="U2659" /TUdmin=0 /isTUend="TRUE" promotor_-35 3329788..3329795 /Source="Nicolas_upshift_promotors" /id="U2660" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.982017982017982" /psig=1 /xcortree=2868 /SigmaFactorBS="taatgcataatttacattaatttattaattatccatttttTG TTGATTattctgactagctaTTATATAATCTTTTTGAAATgattatattagcttagag g" /listShort="S1293, sdpA, sdpB, spbC, S1297" /GFF_Attribute="listLong" /label="promotor_-35" S_feature 3329808..3329886 /Source="Nicolas_S_feature" /locus_tag="new_3464210_3464288" /HighExp="T-1.10H, T2.30H, T4.0H, T5.0H, T-2.40H, T2.0H, T-0.40H, M9-stat, T-5.40H, T1.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1293" upshifts 3329808 /Source="Nicolas_upshifts" /id="U2660" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.982017982017982" /psig=1 /xcortree=2868 /SigmaFactorBS="taatgcataatttacattaatttattaattatccatttttTG TTGATTattctgactagctaTTATATAATCTTTTTGAAATgattatattagcttagag g" /listShort="S1293, sdpA, sdpB, spbC, S1297" /GFF_Attribute="listLong" promotor_-10 3329810..3329829 /Source="Nicolas_upshift_promotors" /id="U2660" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.982017982017982" /psig=1 /xcortree=2868 /SigmaFactorBS="taatgcataatttacattaatttattaattatccatttttTG TTGATTattctgactagctaTTATATAATCTTTTTGAAATgattatattagcttagag g" /listShort="S1293, sdpA, sdpB, spbC, S1297" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-10 complement(3329836..3329850) /Source="Nicolas_upshift_promotors" /id="U2661" /multdbtbs="-" /comp="M15" /sig="SigA" /pcomp="0.483516483516484" /psig="0.503496503496504" /xcortree=2951 /SigmaFactorBS="aaaataataggaaacatatagtcattacagtaataattccct tttttttgaTgtagattacCTCCTCTAAGCTAATataatcatttcaaaaagattatat a" /listShort="S1292" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3329851) /Source="Nicolas_upshifts" /id="U2661" /multdbtbs="-" /comp="M15" /sig="SigA" /pcomp="0.483516483516484" /psig="0.503496503496504" /xcortree=2951 /SigmaFactorBS="aaaataataggaaacatatagtcattacagtaataattccct tttttttgaTgtagattacCTCCTCTAAGCTAATataatcatttcaaaaagattatat a" /listShort="S1292" /GFF_Attribute="listLong" promotor_-35 complement(3329860) /Source="Nicolas_upshift_promotors" /id="U2661" /multdbtbs="-" /comp="M15" /sig="SigA" /pcomp="0.483516483516484" /psig="0.503496503496504" /xcortree=2951 /SigmaFactorBS="aaaataataggaaacatatagtcattacagtaataattccct tttttttgaTgtagattacCTCCTCTAAGCTAATataatcatttcaaaaagattatat a" /listShort="S1292" /GFF_Attribute="listLong" /label="promotor_-35" CDS 3329887..3330363 /gene="sdpA" /locus_tag="BSU_33750" /old_locus_tag="BSU33750" /function="16.11: Scavenge (Catabolism)" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:16469701, 17069462, 23687264" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16469701, 17069462, 23687264; Product type f: factor" /codon_start=1 /transl_table=11 /product="export step of killing factor SdpC" /protein_id="NP_391255.1" /db_xref="EnsemblGenomes-Gn:BSU33750" /db_xref="EnsemblGenomes-Tr:CAB15380" /db_xref="GOA:O34889" /db_xref="InterPro:IPR023902" /db_xref="SubtiList:BG14074" /db_xref="UniProtKB/Swiss-Prot:O34889" /translation="MTICFLLFSSYYFSNISPQNPLFKKNFLQQLSPQGFGFYSKSPT EENISFHTKENLKLPNALPNNFFGIKREGRVQAIELGKIVENIDPKNWKTCENNNSCT NLEKQIKPIKVIKNEDYIHLSKGEYLIYRQKPLSWYWIDFKQTTSFERKVLKIKIV*" gene 3329887..3330363 /gene="sdpA" /locus_tag="BSU_33750" /old_locus_tag="BSU33750" promotor_-10 complement(3329912..3329931) /Source="Nicolas_upshift_promotors" /id="U2662" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.797202797202797" /psig=1 /xcortree=3097 /SigmaFactorBS="agacaattgttgcaaaaaattttttttgaacaGTGGATTCtg aggtgaaatATTGCTAAAGTAATAAGAAGaaaataataggaaacatatagtcattaca g" /listShort="S1292" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3329922) /Source="Nicolas_upshifts" /id="U2662" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.797202797202797" /psig=1 /xcortree=3097 /SigmaFactorBS="agacaattgttgcaaaaaattttttttgaacaGTGGATTCtg aggtgaaatATTGCTAAAGTAATAAGAAGaaaataataggaaacatatagtcattaca g" /listShort="S1292" /GFF_Attribute="listLong" promotor_-35 complement(3329943..3329950) /Source="Nicolas_upshift_promotors" /id="U2662" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.797202797202797" /psig=1 /xcortree=3097 /SigmaFactorBS="agacaattgttgcaaaaaattttttttgaacaGTGGATTCtg aggtgaaatATTGCTAAAGTAATAAGAAGaaaataataggaaacatatagtcattaca g" /listShort="S1292" /GFF_Attribute="listLong" /label="promotor_-35" CDS 3330360..3331331 /gene="sdpB" /locus_tag="BSU_33760" /old_locus_tag="BSU33760" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:15743949, 15849754, 16469701, 16850406, 17069462, 23687264" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15743949, 15849754, 16469701, 16850406, 17069462, 23687264; Product type t : transporter" /codon_start=1 /transl_table=11 /product="export step of killing factor SdpC" /protein_id="NP_391256.1" /db_xref="EnsemblGenomes-Gn:BSU33760" /db_xref="EnsemblGenomes-Tr:CAB15381" /db_xref="GOA:O34616" /db_xref="InterPro:IPR007782" /db_xref="InterPro:IPR011020" /db_xref="InterPro:IPR023894" /db_xref="SubtiList:BG14075" /db_xref="UniProtKB/Swiss-Prot:O34616" /translation="MKILNSLEGYIDTYNPWKNTYALFRSLLGFSTLLVLLFNSTDIL FSYSANNVTCENVYIPTAFCFAKEYSINFEIIRYLMIFILTLVVIGWRPRFTGLFHWY ICYSIQTSALTIDGGEQIATVLSFLILPVTLLDSRRNHWNIKKNNNESFTKKTVLFYI MTIIKIQVFIIYLNAALERLKNKEWAEGTAIYYFFSDPVFGLPEYQLNLMNPLLESNF IVVITWLVTIFELFLAASIISNIRIKRIALVLGILFHIGIIFSIGIVSFGLIMISALI IYLHPVQQNITMNWCSPLFKYIYVKGKRNFKRIGGESVKFLTKLFHS*" gene 3330360..3331331 /gene="sdpB" /locus_tag="BSU_33760" /old_locus_tag="BSU33760" promotor_no_box 3331168..3331268 /Source="Nicolas_upshift_promotors" /id="U2663" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.457542457542458" /psig="0.636363636363636" /xcortree=2869 /SigmaFactorBS="tcatgatatcagcattaattatatatctgcatcctgtacaac aaaatatcactatgaattggtgttctcctttatttaaatatatatatgtaaaaggaaa g" /listShort="spbC, S1297" /GFF_Attribute="listLong" /label="promotor_no_box" upshifts 3331228 /Source="Nicolas_upshifts" /id="U2663" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.457542457542458" /psig="0.636363636363636" /xcortree=2869 /SigmaFactorBS="tcatgatatcagcattaattatatatctgcatcctgtacaac aaaatatcactatgaattggtgttctcctttatttaaatatatatatgtaaaaggaaa g" /listShort="spbC, S1297" /GFF_Attribute="listLong" promotor_-10 complement(3331240..3331257) /Source="Nicolas_upshift_promotors" /id="U2664" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.578421578421578" /psig="0.758241758241758" /xcortree=423 /SigmaFactorBS="aacaattttgtaagaaacttgactgattcacctcctattctt ttgAAAtttctctttccttttaCATATATATATTTAAATAaaggagaacaccaattca t" /listShort="S1292" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3331261) /Source="Nicolas_upshifts" /id="U2664" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.578421578421578" /psig="0.758241758241758" /xcortree=423 /SigmaFactorBS="aacaattttgtaagaaacttgactgattcacctcctattctt ttgAAAtttctctttccttttaCATATATATATTTAAATAaaggagaacaccaattca t" /listShort="S1292" /GFF_Attribute="listLong" S_feature complement(3331263..3331665) /Source="Nicolas_S_feature" /locus_tag="new_3465665_3466067_c" /HighExp="Gly, Lbstat, BT, S8, T1.30H, C30, M9-stat, C90, Sw, HiTm" /AntisenseName="spbC" /AntisenseCor="-0.16053929530879699" /AntisenseRegPval="-2.1" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1294" promotor_-35 complement(3331274..3331276) /Source="Nicolas_upshift_promotors" /id="U2664" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.578421578421578" /psig="0.758241758241758" /xcortree=423 /SigmaFactorBS="aacaattttgtaagaaacttgactgattcacctcctattctt ttgAAAtttctctttccttttaCATATATATATTTAAATAaaggagaacaccaattca t" /listShort="S1292" /GFF_Attribute="listLong" /label="promotor_-35" downshifts complement(3331292) /Source="Nicolas_upshifts" /id="D1751" /incds=0 /nref=1 /ntot=33 /MaxReadThrough="3.26001" /MaxDrop="4.09728" /score="-7.06061287" /energy="-10.3" /TU="NA" /idTUdmin="U2665" /TUdmin=286 /isTUend="FALSE" CDS 3331374..3331985 /gene="spbC" /locus_tag="BSU_33770" /old_locus_tag="BSU33770" /function="16.11: Scavenge (Catabolism)" /function="16.8: Protect" /function="16.4: Excrete" /experiment="publication(s) with functional evidences, PMID:15743949, 16469701, 17069462, 23687264" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15743949, 16469701, 17069462, 23687264; Product type f: factor" /codon_start=1 /transl_table=11 /product="precursor of killing factor SdpC" /protein_id="NP_391257.1" /db_xref="EnsemblGenomes-Gn:BSU33770" /db_xref="EnsemblGenomes-Tr:CAB15382" /db_xref="GOA:O34344" /db_xref="InterPro:IPR023888" /db_xref="SubtiList:BG14076" /db_xref="UniProtKB/Swiss-Prot:O34344" /translation="MKSKLLRLLIVSMVTILVFSLVGLSKESSTSAKENHTFSGEDYF RGLLFGQGEVGKLISNDLDPKLVKEANSTEGKKLVNDVVKFIKKDQPQYMDELKQSID SKDPKKLIENMTKADQLIQKYAKKNENVKYSSNKVTPSCGLYAVCVAAGYLYVVGVNA VALQTAAAVTTAVWKYVAKYSSSASNNSDLEAAAAKTLKLIHQ*" gene 3331374..3331985 /gene="spbC" /locus_tag="BSU_33770" /old_locus_tag="BSU33770" S_feature complement(3331667..3331753) /Source="Nicolas_S_feature" /locus_tag="new_3466069_3466155_c" /HighExp="T1.30H, Gly, T2.0H, BT, S8, C30, Lbstat, C90, T1.0H, M9-stat" /AntisenseName="spbC" /AntisenseCor="-5.4790207146846799E-2" /AntisenseRegPval="-0.4" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1295" downshifts complement(3331710) /Source="Nicolas_upshifts" /id="D1752" /incds=1 /nref=1 /ntot=8 /MaxReadThrough="4.62458" /MaxDrop="2.00358" /score="8.72167152" /energy="-11.6" /TU="U2665" /idTUdmin="U2665" /TUdmin="-132" /isTUend="FALSE" S_feature complement(3331755..3331940) /Source="Nicolas_S_feature" /locus_tag="new_3466157_3466342_c" /HighExp="T1.30H, T2.0H, M9-stat, T1.0H, B60, T2.30H, T5.0H, B36, T3.30H, T0.30H" /AntisenseName="spbC" /AntisenseCor="-4.2394313806342503E-2" /AntisenseRegPval="-0.3" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="SigA" /TUlongPSig="0.999" /label="S1296" downshifts complement(3331798) /Source="Nicolas_upshifts" /id="D1753" /incds=1 /nref=1 /ntot=14 /MaxReadThrough="4.27088" /MaxDrop="2.27366" /score="8.72167152" /energy="-11.6" /TU="U2665" /idTUdmin="U2665" /TUdmin="-220" /isTUend="FALSE" downshifts 3331965 /Source="Nicolas_upshifts" /id="D1754" /incds=0 /nref=207 /ntot=252 /MaxReadThrough="4.65014" /MaxDrop="7.52715" /score="19.8036228" /energy="-20" /TU="U2660,U2663" /idTUdmin="U2660" /TUdmin="-1099" /isTUend="FALSE" downshifts complement(3331985) /Source="Nicolas_upshifts" /id="D1755" /incds=0 /nref=14 /ntot=94 /MaxReadThrough="6.14809" /MaxDrop="5.58575" /score="8.72167152" /energy="-11.6" /TU="U2665" /idTUdmin="U2667" /TUdmin=33 /isTUend="FALSE" S_feature 3332010..3333148 /Source="Nicolas_S_feature" /locus_tag="new_3466412_3467550" /HighExp="Pyr, S8, nit, C30, GM 150, M9-stat, S7, S2, G/S, S1" /AntisenseName="sdpI" /AntisenseCor="-7.9710115369408502E-2" /AntisenseRegPval="-0.7" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="0.636, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S1297" CDS complement(3332032..3332655) /gene="sdpI" /locus_tag="BSU_33780" /old_locus_tag="BSU33780" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:12817086, 15849754, 16850406, 20563570, 23687264" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12817086, 15849754, 16850406, 20563570, 23687264; Product type r: regulator" /codon_start=1 /transl_table=11 /product="integral membrane immunity regulator of autophagy" /protein_id="NP_391258.1" /db_xref="EnsemblGenomes-Gn:BSU33780" /db_xref="EnsemblGenomes-Tr:CAB15383" /db_xref="GOA:O32241" /db_xref="InterPro:IPR012867" /db_xref="InterPro:IPR025962" /db_xref="InterPro:IPR026272" /db_xref="SubtiList:BG14077" /db_xref="UniProtKB/Swiss-Prot:O32241" /translation="MKKNIISIIIVCLSFLTSIILYQYLPEEIPIQWSGNKPAAIVSK PLTIFIIPVVMLIYYLTFYMLTIKSTQKNKALLFLASNNMLILLYILQLSTLLISLGY EVNIDLIIGLGVGIFLIIGGNSMQLAEQNHLIGLRTPWTLKDETVWKLGNRFASKVLV VCGFIIAVLSFFTGEYIILIMIVLVLLALVISTLASYHYYKKLNGSR*" gene complement(3332032..3332655) /gene="sdpI" /locus_tag="BSU_33780" /old_locus_tag="BSU33780" downshifts complement(3332040) /Source="Nicolas_upshifts" /id="D1756" /incds=0 /nref=1 /ntot=95 /MaxReadThrough="6.43517" /MaxDrop="3.3455" /score="8.72167152" /energy="-11.6" /TU="U2665,U2667" /idTUdmin="U2667" /TUdmin="-22" /isTUend="TRUE" CDS complement(3332652..3332924) /gene="sdpR" /locus_tag="BSU_33790" /old_locus_tag="BSU33790" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:12817086, 17069462, 23687264" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12817086, 17069462, 23687264; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator of SdpC synthesis operon (ArsR family)" /protein_id="NP_391259.1" /db_xref="EnsemblGenomes-Gn:BSU33790" /db_xref="EnsemblGenomes-Tr:CAB15384" /db_xref="GOA:O32242" /db_xref="InterPro:IPR001845" /db_xref="InterPro:IPR011991" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG14078" /db_xref="UniProtKB/Swiss-Prot:O32242" /translation="MNNVFKAISDPTRRKILDLLKGGDMTAGDIAEHFNISKPSISHH LNILKQAEVISDHRKGQFIYYSLNTTVLQDSINWMLNFINKGDNDL*" gene complement(3332652..3332924) /gene="sdpR" /locus_tag="BSU_33790" /old_locus_tag="BSU33790" promotor_-10 complement(3332980..3332999) /Source="Nicolas_upshift_promotors" /id="U2665" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.372627372627373" /psig=1 /xcortree=405 /SigmaFactorBS="tacaaaaatcagatattataaccaatttgaggGTTGTTTtta aaaaaattCAAGTTATAATGAAAATAATacatttatacaaatatctaaatgtctaaat g" /listShort="sdpR, sdpI, S1296, S1295, S1294" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3332989) /Source="Nicolas_upshifts" /id="U2665" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.372627372627373" /psig=1 /xcortree=405 /SigmaFactorBS="tacaaaaatcagatattataaccaatttgaggGTTGTTTtta aaaaaattCAAGTTATAATGAAAATAATacatttatacaaatatctaaatgtctaaat g" /listShort="sdpR, sdpI, S1296, S1295, S1294" /GFF_Attribute="listLong" S_feature complement(3332991..3333139) /Source="Nicolas_S_feature" /locus_tag="new_3467393_3467541_c" /HighExp="Salt, B36, Gly, B60, LoTm, S8, GM 5, MG 25, Cold, Mal" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S1298" promotor_-35 complement(3333011..3333017) /Source="Nicolas_upshift_promotors" /id="U2665" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.372627372627373" /psig=1 /xcortree=405 /SigmaFactorBS="tacaaaaatcagatattataaccaatttgaggGTTGTTTtta aaaaaattCAAGTTATAATGAAAATAATacatttatacaaatatctaaatgtctaaat g" /listShort="sdpR, sdpI, S1296, S1295, S1294" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3333144..3333833) /gene="opuCD" /locus_tag="BSU_33800" /old_locus_tag="BSU33800" /function="16.1: Circulate" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:9925583, 10216873, 15849754, 16850406, 28256787" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9925583, 10216873, 15849754, 16850406, 28256787; Product type t : transporter" /codon_start=1 /transl_table=11 /product="glycine betaine/carnitine/choline/choline sulfate ABC transporter (promiscuous permease)" /protein_id="NP_391260.1" /db_xref="EnsemblGenomes-Gn:BSU33800" /db_xref="EnsemblGenomes-Tr:CAB15385" /db_xref="GOA:O34742" /db_xref="InterPro:IPR000515" /db_xref="InterPro:IPR035906" /db_xref="SubtiList:BG12640" /db_xref="UniProtKB/Swiss-Prot:O34742" /translation="MEVLQQLGTYYSQNGGYVLQEFYRHFLMSVYGVLFAAIVGIPLG ILIARYRRLSGWVFAVTNVIQTIPALAMLAVLMLVMGLGANTVILSLFLYSLLPIIRN TYTGIISIEHAYLESGKAMGMTKFQVLRMVELPLALSVIMAGLRTALVIAIGITAIGT FVGAGGLGDIIVRGSNATNGTAIILAGAIPTALMAVIADLVMGWLERALSPIKKKKGN FIIADRKTTSI*" gene complement(3333144..3333833) /gene="opuCD" /locus_tag="BSU_33800" /old_locus_tag="BSU33800" downshifts complement(3333184) /Source="Nicolas_upshifts" /id="D1757" /incds=0 /nref=95 /ntot=199 /MaxReadThrough="5.55394" /MaxDrop="6.7177" /score="8.72167152" /energy="-11.6" /TU="U2667" /idTUdmin="U2667" /TUdmin="-1166" /isTUend="FALSE" promotor_-35 3333776..3333784 /Source="Nicolas_upshift_promotors" /id="U2666" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.763236763236763" /psig="0.763236763236763" /xcortree=767 /SigmaFactorBS="tcagaaaatggcggtaaaattcctGCAGCACGTaaccgccgt tttgCGAATAGTATGTGCCAAGCTgctgtagtacttccatatgatccacctcttttct t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3333798..3333817 /Source="Nicolas_upshift_promotors" /id="U2666" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.763236763236763" /psig="0.763236763236763" /xcortree=767 /SigmaFactorBS="tcagaaaatggcggtaaaattcctGCAGCACGTaaccgccgt tttgCGAATAGTATGTGCCAAGCTgctgtagtacttccatatgatccacctcttttct t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3333812 /Source="Nicolas_upshifts" /id="U2666" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.763236763236763" /psig="0.763236763236763" /xcortree=767 /SigmaFactorBS="tcagaaaatggcggtaaaattcctGCAGCACGTaaccgccgt tttgCGAATAGTATGTGCCAAGCTgctgtagtacttccatatgatccacctcttttct t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" CDS complement(3333851..3334762) /gene="opuCC" /locus_tag="BSU_33810" /old_locus_tag="BSU33810" /function="16.1: Circulate" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:9925583, 10216873, 28256787" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9925583, 10216873, 28256787; Product type t: transporter" /codon_start=1 /transl_table=11 /product="glycine betaine/carnitine/choline/choline sulfate ABC transporter (osmoprotectant-binding lipoprotein)" /protein_id="NP_391261.1" /db_xref="EnsemblGenomes-Gn:BSU33810" /db_xref="EnsemblGenomes-Tr:CAB15386" /db_xref="GOA:O32243" /db_xref="InterPro:IPR007210" /db_xref="PDB:3PPN" /db_xref="PDB:3PPO" /db_xref="PDB:3PPP" /db_xref="PDB:3PPQ" /db_xref="PDB:3PPR" /db_xref="SubtiList:BG12639" /db_xref="UniProtKB/Swiss-Prot:O32243" /translation="MTKIKWLGAFALVFVMLLGGCSLPGLGGASDDTIKIGAQSMTES EIVANMIAQLIEHDTDLNTALVKNLGSNYVQHQAMLGGDIDISATRYSGTDLTSTLGK EAEKDPKKALNIVQNEFQKRFSYKWFDSYGFDNTYAFTVTKKFAEKEHINTVSDLKKN ASQYKLGVDNAWLKRKGDGYKGFVSTYGFEFGTTYPMQIGLVYDAVKNGKMDAVLAYS TDGRIKAYDLKILKDDKRFFPPYDCSPVIPEKVLKEHPELEGVINKLIGQIDTETMQE LNYEVDGKLKEPSVVAKEFLEKHHYFD*" gene complement(3333851..3334762) /gene="opuCC" /locus_tag="BSU_33810" /old_locus_tag="BSU33810" CDS complement(3334782..3335435) /gene="opuCB" /locus_tag="BSU_33820" /old_locus_tag="BSU33820" /function="16.1: Circulate" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:9925583, 10216873, 15849754, 16850406, 28256787" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9925583, 10216873, 15849754, 16850406, 28256787; Product type t : transporter" /codon_start=1 /transl_table=11 /product="glycine betaine/carnitine/choline/choline sulfate ABC transporter (promiscuous permease)" /protein_id="NP_391262.1" /db_xref="EnsemblGenomes-Gn:BSU33820" /db_xref="EnsemblGenomes-Tr:CAB15387" /db_xref="GOA:O34878" /db_xref="InterPro:IPR000515" /db_xref="InterPro:IPR035906" /db_xref="SubtiList:BG12638" /db_xref="UniProtKB/Swiss-Prot:O34878" /translation="MNQMMTFLQTNGGELLYKTGEHLYISLIAVVLGIIVAVPLGVAL TRMKKGAGAVIGFVNIVQTLPSLAILAFFIPLLGVGKVPAIVALFFYSVLPILRNTYT GIKGVNKNLLESGKGIGMTGWEQIRLVEIPLAIPIIMAGIRTSTIYLIGWATLASFIG GGGLGDYIFIGLNLYQPEYIIGGAVPVTILAIIIDYVLAVTERKVTPKGLQGMKEVS* " gene complement(3334782..3335435) /gene="opuCB" /locus_tag="BSU_33820" /old_locus_tag="BSU33820" CDS complement(3335458..3336600) /gene="opuCA" /locus_tag="BSU_33830" /old_locus_tag="BSU33830" /function="16.1: Circulate" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:10216873, 9925583, 21658392, 27378384, 27683249" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10216873, 9925583, 21658392, 27378384, 27683249; Product type t : transporter" /codon_start=1 /transl_table=11 /product="glycine betaine/carnitine/choline/choline sulfate ABC transporter (ATP-binding protein)" /protein_id="NP_391263.1" /db_xref="EnsemblGenomes-Gn:BSU33830" /db_xref="EnsemblGenomes-Tr:CAB15388" /db_xref="GOA:O34992" /db_xref="InterPro:IPR000644" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR005892" /db_xref="InterPro:IPR017871" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG12637" /db_xref="UniProtKB/Swiss-Prot:O34992" /translation="MLKLEQVSKVYKGGKKAVNSIDLDIAKGEFICFIGPSGCGKTTT MKMINRLIEPSSGRIFIDGENIMEQDPVELRRKIGYVIQQIGLFPHMTIQQNISLVPK LLKWPEEKRKERARELLKLVDMGPEYLDRYPHELSGGQQQRIGVLRALAAEPPLILMD EPFGALDPITRDSLQEEFKKLQRTLNKTIVFVTHDMDEAIKLADRIVILKAGEIVQVG TPDEILRNPANEFVEEFIGKERLIQSRPDIERVEQMMNRTPVTVSADKTLSQAIQLMR EKRVDSLLVVDRQNVLKGYVDVEMIDQNRKKASIVGDVYRSDIYTVQKGALLRDTVRK ILKQGIKYVPVVDEQNHLAGIVTRASLVDIVYDSIWGDEENQLMTI*" gene complement(3335458..3336600) /gene="opuCA" /locus_tag="BSU_33830" /old_locus_tag="BSU33830" promotor_-10 complement(3336644..3336663) /Source="Nicolas_upshift_promotors" /id="U2667" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.937062937062937" /psig="0.999000999001" /xcortree=3049 /SigmaFactorBS="taatctataaataacatataatttcaacacattgtaaaCTTT ttattttacaaagtTCAAACTATAATAAGGATTAtacttttcagaaaatttaaaggaa a" /listShort="opuCA, opuCB, opuCC, opuCD, S1298, sdpR, sdpI" /listLong="S1296" /label="promotor_-10" upshifts complement(3336659) /Source="Nicolas_upshifts" /id="U2667" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.937062937062937" /psig="0.999000999001" /xcortree=3049 /SigmaFactorBS="taatctataaataacatataatttcaacacattgtaaaCTTT ttattttacaaagtTCAAACTATAATAAGGATTAtacttttcagaaaatttaaaggaa a" /listShort="opuCA, opuCB, opuCC, opuCD, S1298, sdpR, sdpI" /listLong="S1296" promotor_-35 complement(3336678..3336681) /Source="Nicolas_upshift_promotors" /id="U2667" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.937062937062937" /psig="0.999000999001" /xcortree=3049 /SigmaFactorBS="taatctataaataacatataatttcaacacattgtaaaCTTT ttattttacaaagtTCAAACTATAATAAGGATTAtacttttcagaaaatttaaaggaa a" /listShort="opuCA, opuCB, opuCC, opuCD, S1298, sdpR, sdpI" /listLong="S1296" /label="promotor_-35" promotor_-35 3336797..3336804 /Source="Nicolas_upshift_promotors" /id="U2668" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.697302697302697" /psig="0.993006993006993" /xcortree=3046 /SigmaFactorBS="atacctcccacttcctctgcattcagctaTTTTCAACaccag gaagaaaTATGATATATTGACACCATCaattgccatttgaagggatgatcagctgtga a" /listShort="yvbF, S1299, yvbH" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3336817..3336836 /Source="Nicolas_upshift_promotors" /id="U2668" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.697302697302697" /psig="0.993006993006993" /xcortree=3046 /SigmaFactorBS="atacctcccacttcctctgcattcagctaTTTTCAACaccag gaagaaaTATGATATATTGACACCATCaattgccatttgaagggatgatcagctgtga a" /listShort="yvbF, S1299, yvbH" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3336828 /Source="Nicolas_upshifts" /id="U2668" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.697302697302697" /psig="0.993006993006993" /xcortree=3046 /SigmaFactorBS="atacctcccacttcctctgcattcagctaTTTTCAACaccag gaagaaaTATGATATATTGACACCATCaattgccatttgaagggatgatcagctgtga a" /listShort="yvbF, S1299, yvbH" /GFF_Attribute="listLong" CDS 3336864..3337421 /gene="opcR" /locus_tag="BSU_33840" /old_locus_tag="BSU33840" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:23960087" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 23960087; Product type r: regulator" /codon_start=1 /transl_table=11 /product="negative transcriptional regulator of choline uptake systems" /protein_id="NP_391264.1" /db_xref="EnsemblGenomes-Gn:BSU33840" /db_xref="EnsemblGenomes-Tr:CAB15389" /db_xref="GOA:O34709" /db_xref="InterPro:IPR026282" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG14079" /db_xref="UniProtKB/Swiss-Prot:O34709" /translation="MKKTALDIIEHAEEHLIEKIAENMHTFGMPSTVGRVLGIIYMNR KPMTLSELSEATGMSKTRMSQVVREMIDANIAEKVFEKGVRKDLYDVEQDYYQTFISL FAANWTKVVSKNKVLYKKLNRELSDLLQRDGLTPEAEEKVNQLLNELKEWLHYYDWLS RLIEFFESEEVFRYVPKTKECSSLK*" gene 3336864..3337421 /gene="opcR" /locus_tag="BSU_33840" /old_locus_tag="BSU33840" S_feature 3337422..3338186 /Source="Nicolas_S_feature" /locus_tag="new_3471824_3472588" /HighExp="HiOs, GM 5, GM 10, Salt, MG 15, MG 10, MG 25, T0.0H, T-2.40H, GM 45" /AntisenseName="yvbG" /AntisenseCor="-0.14921239095219299" /AntisenseRegPval="-1.8" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.993" /TUlongSig="NA" /TUlongPSig="NA" /label="S1299" CDS complement(3337439..3338074) /gene="yvbG" /locus_tag="BSU_33850" /old_locus_tag="BSU33850" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative integral membrane protein" /protein_id="NP_391265.1" /db_xref="EnsemblGenomes-Gn:BSU33850" /db_xref="EnsemblGenomes-Tr:CAB15390" /db_xref="GOA:O32244" /db_xref="InterPro:IPR002771" /db_xref="SubtiList:BG14080" /db_xref="UniProtKB/Swiss-Prot:O32244" /translation="MMFSFIVHVFISLFAVSNPIGNVPIFLTLTEGYTAAERKAIARK AAILSFFILAAFLVFGHLIFKLFDINIHALRVAGGIFIFGIAYNLLNAKESHVQSLHH DEHKESKEKADISVTPLSIPIIAGPGTIATVMSLSAGHSGIGHYAAVMIGIAAVIALT FLFFHYSAFISSKLGKTEMNVITRLMGLILAVVAVGMIGAGLKGMFPVLTS*" gene complement(3337439..3338074) /gene="yvbG" /locus_tag="BSU_33850" /old_locus_tag="BSU33850" downshifts complement(3337452) /Source="Nicolas_upshifts" /id="D1758" /incds=0 /nref=21 /ntot=50 /MaxReadThrough="2.02169" /MaxDrop="4.45088" /score="10.9231366" /energy="-16.4" /TU="NA" /idTUdmin="U2669" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(3338115..3338133) /Source="Nicolas_upshift_promotors" /id="U2669" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=181 /SigmaFactorBS="atggcgcgtttctgacaggctataaaGGTTTACcgggaaatc gcctccGGGTAAAAGGGTGGAGAATcattctatttcctgtgcagagactatcaacaag g" /listShort="yvbG" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3338121) /Source="Nicolas_upshifts" /id="U2669" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=181 /SigmaFactorBS="atggcgcgtttctgacaggctataaaGGTTTACcgggaaatc gcctccGGGTAAAAGGGTGGAGAATcattctatttcctgtgcagagactatcaacaag g" /listShort="yvbG" /GFF_Attribute="listLong" promotor_-35 complement(3338149..3338155) /Source="Nicolas_upshift_promotors" /id="U2669" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=181 /SigmaFactorBS="atggcgcgtttctgacaggctataaaGGTTTACcgggaaatc gcctccGGGTAAAAGGGTGGAGAATcattctatttcctgtgcagagactatcaacaag g" /listShort="yvbG" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 3338160..3338167 /Source="Nicolas_upshift_promotors" /id="U2670" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.97902097902098" /psig=1 /xcortree=2261 /SigmaFactorBS="ttacccggaggcgatttcccggtaaacctttaTAGCCTGTca gaaacgcgcCATGCTACAATGAAGTGACAaattgaataggaaggacgtatacagatgt t" /listShort="yvbH, yvbI" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3338179..3338198 /Source="Nicolas_upshift_promotors" /id="U2670" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.97902097902098" /psig=1 /xcortree=2261 /SigmaFactorBS="ttacccggaggcgatttcccggtaaacctttaTAGCCTGTca gaaacgcgcCATGCTACAATGAAGTGACAaattgaataggaaggacgtatacagatgt t" /listShort="yvbH, yvbI" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3338188 /Source="Nicolas_upshifts" /id="U2670" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.97902097902098" /psig=1 /xcortree=2261 /SigmaFactorBS="ttacccggaggcgatttcccggtaaacctttaTAGCCTGTca gaaacgcgcCATGCTACAATGAAGTGACAaattgaataggaaggacgtatacagatgt t" /listShort="yvbH, yvbI" /GFF_Attribute="listLong" CDS 3338224..3338838 /gene="yvbH" /locus_tag="BSU_33860" /old_locus_tag="BSU33860" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_391266.1" /db_xref="EnsemblGenomes-Gn:BSU33860" /db_xref="EnsemblGenomes-Tr:CAB15391" /db_xref="InterPro:IPR011993" /db_xref="InterPro:IPR012544" /db_xref="InterPro:IPR021722" /db_xref="InterPro:IPR037063" /db_xref="SubtiList:BG14081" /db_xref="UniProtKB/Swiss-Prot:O32245" /translation="MFKKIAADALGLSDIGKIIEPQDYDKTDADDYVMHEDNEKIYFL IKTKADEYCFTNLALIHVDGERATSSKRTLKRYPYSQYKISDVFLETAGKVDLDVEIK FKLGGEQFDIDVHKDQIEKLKDLYKALLRIAETTYENDILINQAEQSLDKAVTILHHT RPEHVNIETQYKELTEFGFTWLTSVRSQYHIKDFGDVFEKYINN*" gene 3338224..3338838 /gene="yvbH" /locus_tag="BSU_33860" /old_locus_tag="BSU33860" downshifts 3338824 /Source="Nicolas_upshifts" /id="D1759" /incds=0 /nref=110 /ntot=197 /MaxReadThrough="2.66824" /MaxDrop="5.86088" /score="-4.16829989" /energy="-7.9" /TU="U2670" /idTUdmin="U2668" /TUdmin="-4" /isTUend="TRUE" promotor_-35 3338892..3338895 /Source="Nicolas_upshift_promotors" /id="U2671" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.623376623376623" /psig=1 /xcortree=2318 /SigmaFactorBS="ctatcgtgctcgtgtctttttttgtatgaatattGATTactt tacaacttttTTCTTTTATAATAAAACTATtagtctattttccctatattacagataa a" /listShort="yvbI" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3338910..3338929 /Source="Nicolas_upshift_promotors" /id="U2671" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.623376623376623" /psig=1 /xcortree=2318 /SigmaFactorBS="ctatcgtgctcgtgtctttttttgtatgaatattGATTactt tacaacttttTTCTTTTATAATAAAACTATtagtctattttccctatattacagataa a" /listShort="yvbI" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3338918 /Source="Nicolas_upshifts" /id="U2671" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.623376623376623" /psig=1 /xcortree=2318 /SigmaFactorBS="ctatcgtgctcgtgtctttttttgtatgaatattGATTactt tacaacttttTTCTTTTATAATAAAACTATtagtctattttccctatattacagataa a" /listShort="yvbI" /GFF_Attribute="listLong" CDS 3338970..3339668 /gene="yvbI" /locus_tag="BSU_33870" /old_locus_tag="BSU33870" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 15849754, 16850406" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_391267.1" /db_xref="EnsemblGenomes-Gn:BSU33870" /db_xref="EnsemblGenomes-Tr:CAB15392" /db_xref="GOA:O32246" /db_xref="InterPro:IPR029038" /db_xref="SubtiList:BG14082" /db_xref="UniProtKB/Swiss-Prot:O32246" /translation="MYCPQCGHQTDGGNFCEKCGSPLPGQSGHQHAAQTGAAAKQAAK QFGSFVLSVLKRPYQECKATGGEQLISAIITMVLFSLLTPLMFYILFSDGPGSVSFTA IFLEPTIYFILFLFGLHACIFFALKIAGNQVSFKDSFSRFGAFLIPFTAILILALFFF LLHTDICFTILAVGLIGAFFAIPPAMLSSYQHSYKGKVDFIYSTIVIYLIICVTFQLI IEHYVKEIFRYMLF*" gene 3338970..3339668 /gene="yvbI" /locus_tag="BSU_33870" /old_locus_tag="BSU33870" downshifts 3339641 /Source="Nicolas_upshifts" /id="D1760" /incds=0 /nref=72 /ntot=203 /MaxReadThrough="1.50622" /MaxDrop="4.71846" /score="17.2112529" /energy="-17.2" /TU="U2671" /idTUdmin="U2671" /TUdmin="-23" /isTUend="FALSE" CDS complement(3339704..3341521) /gene="yvbJ" /locus_tag="BSU_33880" /old_locus_tag="BSU33880" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 15155184" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_391268.1" /db_xref="EnsemblGenomes-Gn:BSU33880" /db_xref="EnsemblGenomes-Tr:CAB15393" /db_xref="GOA:O32247" /db_xref="InterPro:IPR013783" /db_xref="InterPro:IPR026870" /db_xref="SubtiList:BG14083" /db_xref="UniProtKB/Swiss-Prot:O32247" /translation="MLFCKNCGSQNNEGAKFCKQCGTPIGGGSKQANQETASTAETRQ APRKPIPKKTIILWSSIAAACVILFAAYKTGAYFTSKDRLVDKFEQAVNDGDQDQIAT LLTPVNDNLKLTKNNVKPFLTYLKDHPDKKDELFASLRDETAQKDIVYAEKDGKSLLV FDHYDLKVAPVYFEVSSNYKNTDLYVNKEEAGSVKKADQAQTLGPYIPGEYTVSAKLK NDVVDLVKKEDIQAIGDSSFRVDLSLEADDVTFSLANDIKSGKGDLLINGKSIHKDPF KSVTYGPLLTDGSMTASVEAEFPWGKTKTAGVPIDDKEMELTLIPDQDTQEQIMNTIV KTTKQYSKALSDGNTAQMTEASANWKAETKDTVDSMKSADSYLKDRYLETDFDLDTFA LSQKNDGTWQVSVTGKELHQSSSYNDYTKSEMTDDSPSYEYLLSYDKKQKKWIFEDAE STFESAGTNIKKIKNDKPETYTSAWAGSKNKGSESSASGDVTDEQVTLFMGSYLQSQA DAVNQNNFSLMEDSLEKGSSLYSDQQHLVSKLNKEGTTEDFNNYEVKSWSQNGSAITI KTYEEFYITKSGGSPKLRTYNWTYTGVVKNGRIYLTSIQ*" gene complement(3339704..3341521) /gene="yvbJ" /locus_tag="BSU_33880" /old_locus_tag="BSU33880" downshifts complement(3339723) /Source="Nicolas_upshifts" /id="D1761" /incds=0 /nref=31 /ntot=189 /MaxReadThrough="2.6958" /MaxDrop="3.67366" /score="15.9345511" /energy="-17.2" /TU="NA" /idTUdmin="U2673" /TUdmin="-5" /isTUend="TRUE" downshifts complement(3339894) /Source="Nicolas_upshifts" /id="D1762" /incds=1 /nref=1 /ntot=106 /MaxReadThrough="4.6758" /MaxDrop="2.2812" /score="15.9345511" /energy="-17.2" /TU="U2673" /idTUdmin="U2673" /TUdmin="-176" /isTUend="FALSE" misc_feature complement(3341563..3341582) /Source="Nicolas_upshift_promotors" /id="U2673" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.546453546453546" /psig="0.995004995004995" /xcortree=2319 /SigmaFactorBS="cctttttagtctgatagacatttaattttttcattcgttccc aatttcattctgTTTTATTATAAAATATGAAAagcagtaaatgttatcaaattagtag a" /listShort="yvbJ" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" misc_feature 3341567..3341586 /Source="Nicolas_upshift_promotors" /id="U2672" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.679320679320679" /psig="0.994005994005994" /xcortree=3040 /SigmaFactorBS="aaaataacatgactttcctcctattctactaatttgataaca tttactgcttttcATATTTTATAATAAAACAGAatgaaattgggaacgaatgaaaaaa t" /listShort="yvbK" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 3341572 /Source="Nicolas_upshifts" /id="U2672" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.679320679320679" /psig="0.994005994005994" /xcortree=3040 /SigmaFactorBS="aaaataacatgactttcctcctattctactaatttgataaca tttactgcttttcATATTTTATAATAAAACAGAatgaaattgggaacgaatgaaaaaa t" /listShort="yvbK" /GFF_Attribute="listLong" upshifts complement(3341576) /Source="Nicolas_upshifts" /id="U2673" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.546453546453546" /psig="0.995004995004995" /xcortree=2319 /SigmaFactorBS="cctttttagtctgatagacatttaattttttcattcgttccc aatttcattctgTTTTATTATAAAATATGAAAagcagtaaatgttatcaaattagtag a" /listShort="yvbJ" /GFF_Attribute="listLong" CDS 3341641..3342108 /gene="yvbK" /locus_tag="BSU_33890" /old_locus_tag="BSU33890" /EC_number="2.3.1.-" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative N-acyltransferase" /protein_id="NP_391269.1" /db_xref="EnsemblGenomes-Gn:BSU33890" /db_xref="EnsemblGenomes-Tr:CAB15394" /db_xref="GOA:O32248" /db_xref="InterPro:IPR000182" /db_xref="InterPro:IPR016181" /db_xref="PDB:1YVK" /db_xref="SubtiList:BG14084" /db_xref="UniProtKB/Swiss-Prot:O32248" /translation="MNMQKLRIELGEETNDELYDLLLLADPSKDIVDEYLERGECYTA WAGDELAGVYVLLKTRPQTVEIVNIAVKESLQKKGFGKQLVLDAIEKAKKLGADTIEI GTGNSSIHQLSLYQKCGFRIQAIDHDFFLRHYDEDIFENGIQCRDMVRLYLDL*" gene 3341641..3342108 /gene="yvbK" /locus_tag="BSU_33890" /old_locus_tag="BSU33890" downshifts 3342105 /Source="Nicolas_upshifts" /id="D1763" /incds=0 /nref=199 /ntot=250 /MaxReadThrough="1.84358" /MaxDrop="5.3321" /score="15.9040274" /energy="-13.3" /TU="U2672" /idTUdmin="U2672" /TUdmin="-23" /isTUend="FALSE" CDS complement(3342153..3343445) /gene="eno" /locus_tag="BSU_33900" /old_locus_tag="BSU33900" /EC_number="4.2.1.11" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:8021172, 9588797, 12682299, 15301535, 19193632, 19215769, 25355936" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8021172, 9588797, 12682299, 15301535, 19193632, 19215769, 25355936; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="enolase" /protein_id="NP_391270.1" /db_xref="EnsemblGenomes-Gn:BSU33900" /db_xref="EnsemblGenomes-Tr:CAB15395" /db_xref="GOA:P37869" /db_xref="InterPro:IPR000941" /db_xref="InterPro:IPR020809" /db_xref="InterPro:IPR020810" /db_xref="InterPro:IPR020811" /db_xref="InterPro:IPR029017" /db_xref="InterPro:IPR034390" /db_xref="InterPro:IPR036849" /db_xref="PDB:4A3R" /db_xref="SubtiList:BG10899" /db_xref="UniProtKB/Swiss-Prot:P37869" /translation="MPYIVDVYAREVLDSRGNPTVEVEVYTETGAFGRALVPSGASTG EYEAVELRDGDKDRYLGKGVLTAVNNVNEIIAPELLGFDVTEQNAIDQLLIELDGTEN KGKLGANAILGVSMACARAAADFLQIPLYQYLGGFNSKTLPVPMMNIVNGGEHADNNV DIQEFMIMPVGAPNFREALRMGAQIFHSLKSVLSAKGLNTAVGDEGGFAPNLGSNEEA LQTIVEAIEKAGFKPGEEVKLAMDAASSEFYNKEDGKYHLSGEGVVKTSAEMVDWYEE LVSKYPIISIEDGLDENDWEGHKLLTERLGKKVQLVGDDLFVTNTKKLSEGIKNGVGN SILIKVNQIGTLTETFDAIEMAKRAGYTAVISHRSGETEDSTIADIAVATNAGQIKTG APSRTDRVAKYNQLLRIEDQLAETAQYHGINSFYNLNK*" gene complement(3342153..3343445) /gene="eno" /locus_tag="BSU_33900" /old_locus_tag="BSU33900" downshifts complement(3342163) /Source="Nicolas_upshifts" /id="D1764" /incds=0 /nref=254 /ntot=269 /MaxReadThrough="2.21852" /MaxDrop="9.34136" /score="29.8674712" /energy="-15" /TU="NA" /idTUdmin="U2674" /TUdmin="-3" /isTUend="TRUE" CDS complement(3343475..3345010) /gene="pgm" /locus_tag="BSU_33910" /old_locus_tag="BSU33910" /EC_number="5.4.2.12" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:9830105, 10869096, 12682299, 19193632, 22720735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9830105, 10869096, 12682299, 19193632, 22720735; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="phosphoglycerate mutase" /protein_id="NP_391271.1" /db_xref="EnsemblGenomes-Gn:BSU33910" /db_xref="EnsemblGenomes-Tr:CAB15396" /db_xref="GOA:P39773" /db_xref="InterPro:IPR005995" /db_xref="InterPro:IPR006124" /db_xref="InterPro:IPR011258" /db_xref="InterPro:IPR017849" /db_xref="InterPro:IPR017850" /db_xref="InterPro:IPR036646" /db_xref="SubtiList:BG10898" /db_xref="UniProtKB/Swiss-Prot:P39773" /translation="MSKKPAALIILDGFGLRNETVGNAVALAKKPNFDRYWNQYPHQT LTASGEAVGLPEGQMGNSEVGHLNIGAGRIVYQSLTRVNVAIREGEFERNQTFLDAIS NAKENNKALHLFGLLSDGGVHSHINHLFALLKLAKKEGLTKVYIHGFLDGRDVGPQTA KTYINQLNDQIKEIGVGEIASISGRYYSMDRDKRWDRVEKAYRAMAYGEGPSYRSALD VVDDSYANGIYDEFVIPSVITKENGEPVAKIQDGDSVIFYNFRPDRAIQISNTFTNKD FRDFDRGENYPKNLYFVCLTHFSETVDGYVAFKPINLDNTVGEVLSQHGLKQLRIAET EKYPHVTFFMSGGREAEFPGEERILINSPKVATYDLKPEMSAYEVKDALVKEIEADKH DAIILNFANPDMVGHSGMVEPTIKAIEAVDECLGEVVDAILAKGGHAIITADHGNADI LITESGEPHTAHTTNPVPVIVTKEGITLREGGILGDLAPTLLDLLGVEKPKEMTGTSL IQK*" gene complement(3343475..3345010) /gene="pgm" /locus_tag="BSU_33910" /old_locus_tag="BSU33910" CDS complement(3345003..3345764) /gene="tpiA" /locus_tag="BSU_33920" /old_locus_tag="BSU33920" /EC_number="5.3.1.1" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 8021172, 12682299; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="triose phosphate isomerase" /protein_id="NP_391272.1" /db_xref="EnsemblGenomes-Gn:BSU33920" /db_xref="EnsemblGenomes-Tr:CAB15397" /db_xref="GOA:P27876" /db_xref="InterPro:IPR000652" /db_xref="InterPro:IPR013785" /db_xref="InterPro:IPR020861" /db_xref="InterPro:IPR022896" /db_xref="InterPro:IPR035990" /db_xref="SubtiList:BG10897" /db_xref="UniProtKB/Swiss-Prot:P27876" /translation="MRKPIIAGNWKMNKTLGEAVSFVEEVKSSIPAADKAEAVVCAPA LFLEKLASAVKGTDLKVGAQNMHFEESGAFTGEISPVALKDLGVDYCVIGHSERREMF AETDETVNKKAHAAFKHGIVPIICVGETLEEREAGKTNDLVADQVKKGLAGLSEEQVA ASVIAYEPIWAIGTGKSSTAKDANDVCAHIRKTVAESFSQEAADKLRIQYGGSVKPAN IKEYMAESDIDGALVGGASLEPQSFVQLLEEGQYE*" gene complement(3345003..3345764) /gene="tpiA" /locus_tag="BSU_33920" /old_locus_tag="BSU33920" CDS complement(3345795..3346979) /gene="pgk" /locus_tag="BSU_33930" /old_locus_tag="BSU33930" /EC_number="2.7.2.3" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:10559176, 12682299, 22720735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10559176, 12682299, 22720735; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="phosphoglycerate kinase" /protein_id="NP_391273.1" /db_xref="EnsemblGenomes-Gn:BSU33930" /db_xref="EnsemblGenomes-Tr:CAB15398" /db_xref="GOA:P40924" /db_xref="InterPro:IPR001576" /db_xref="InterPro:IPR015824" /db_xref="InterPro:IPR015911" /db_xref="InterPro:IPR036043" /db_xref="SubtiList:BG11062" /db_xref="UniProtKB/Swiss-Prot:P40924" /translation="MNKKTLKDIDVKGKVVFCRVDFNVPMKDGEVTDDTRIRAALPTI KHLADQGAKVLLASHLGRPKGEVVEELRLTPVAARLGELLGKEVKKADEAYGDAVKAQ ISEMKDGDVLVLENVRFYPGEEKNDPELAKAFAELADVYVNDAFGAAHRAHASTAGIA EHLPAVAGFLMEKELDVLGKAVSNPDRPFTAIIGGAKVKDKIGVIESLLDKVDNLIIG GGLAYTFVKALGYEVGKSLLEEDKIELAKSFMDRAKEKGVNFYMPEDVLVADDFSNDA NVKIVPISEIPSDLEAIDIGTKTRETYADVIKNSKLVVWNGPMGVFEIDLFAQGTKAV AEALAEAKDTYSVIGGGDSAAAVEKFGLADKMSHISTGGGASLEFMEGKELPGVAALN DK*" gene complement(3345795..3346979) /gene="pgk" /locus_tag="BSU_33930" /old_locus_tag="BSU33930" S_feature complement(3346980..3347220) /Source="Nicolas_S_feature" /locus_tag="new_3481382_3481622_c" /HighExp="Lbstat, Lbtran, C90, LBGtran, LBGexp, G150, M40t45, LPhT, M0t45, Lbexp" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, Sig-, SigA, SigK" /TUshortPSig="0.979, 0.136, 0.993, 0.902" /TUlongSig="NA" /TUlongPSig="NA" /label="S1300" upshifts complement(3347220) /Source="Nicolas_upshifts" /id="U2674" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.93906093906094" /psig="0.97902097902098" /xcortree=2685 /SigmaFactorBS="ggacctgACTTGgttctttcgaatagaAGCGCTATAATGAAA GCGGAcaagggaaggggacggactccctttccctttttccatgaagaccggctttcag a" /listShort="S1300, pgk, tpiA, pgm, eno" /GFF_Attribute="listLong" S_feature complement(3347222..3347295) /Source="Nicolas_S_feature" /locus_tag="new_3481624_3481697_c" /HighExp="C90, LBGtran, Lbstat, LBGexp, Lbtran, G150, M40t45, Etha, ferm, Gly" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="Sig-, SigA, SigK" /TUshortPSig="0.136, 0.993, 0.902" /TUlongSig="NA" /TUlongPSig="NA" /label="S1301" promotor_-10 complement(3347234..3347253) /Source="Nicolas_upshift_promotors" /id="U2674" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.93906093906094" /psig="0.97902097902098" /xcortree=2685 /SigmaFactorBS="ggacctgACTTGgttctttcgaatagaAGCGCTATAATGAAA GCGGAcaagggaaggggacggactccctttccctttttccatgaagaccggctttcag a" /listShort="S1300, pgk, tpiA, pgm, eno" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 complement(3347269..3347273) /Source="Nicolas_upshift_promotors" /id="U2674" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.93906093906094" /psig="0.97902097902098" /xcortree=2685 /SigmaFactorBS="ggacctgACTTGgttctttcgaatagaAGCGCTATAATGAAA GCGGAcaagggaaggggacggactccctttccctttttccatgaagaccggctttcag a" /listShort="S1300, pgk, tpiA, pgm, eno" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3347296..3348303) /gene="gapA" /locus_tag="BSU_33940" /old_locus_tag="BSU33940" /EC_number="1.2.1.12" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:9588797, 10799476, 12123463, 12634343, 17142398, 27449348, 28760849" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9588797, 10799476, 12123463, 12634343, 17142398, 27449348, 28760849; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="glyceraldehyde-3-phosphate dehydrogenase (NAD-dependent, glycolytic)" /protein_id="NP_391274.1" /db_xref="EnsemblGenomes-Gn:BSU33940" /db_xref="EnsemblGenomes-Tr:CAB15399" /db_xref="GOA:P09124" /db_xref="InterPro:IPR006424" /db_xref="InterPro:IPR020828" /db_xref="InterPro:IPR020829" /db_xref="InterPro:IPR020830" /db_xref="InterPro:IPR020831" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG10827" /db_xref="UniProtKB/Swiss-Prot:P09124" /translation="MAVKVGINGFGRIGRNVFRAALNNPEVEVVAVNDLTDANMLAHL LQYDSVHGKLDAEVSVDGNNLVVNGKTIEVSAERDPAKLSWGKQGVEIVVESTGFFTK RADAAKHLEAGAKKVIISAPANEEDITIVMGVNEDKYDAANHDVISNASCTTNCLAPF AKVLNDKFGIKRGMMTTVHSYTNDQQILDLPHKDYRRARAAAENIIPTSTGAAKAVSL VLPELKGKLNGGAMRVPTPNVSLVDLVAELNQEVTAEEVNAALKEAAEGDLKGILGYS EEPLVSGDYNGNKNSSTIDALSTMVMEGSMVKVISWYDNESGYSNRVVDLAAYIAKKG L*" gene complement(3347296..3348303) /gene="gapA" /locus_tag="BSU_33940" /old_locus_tag="BSU33940" promotor_-35 3348222..3348225 /Source="Nicolas_upshift_promotors" /id="U2675" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.985014985014985" /psig="0.001998001998002" /xcortree=75 /SigmaFactorBS="catgttagcatctgttaaatcgttaaccgctactacctCAAC ttcaggattgtttaatGCTgcgcggaatacgttacgtccaatacgaccaaaaccgtta a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3348242..3348244 /Source="Nicolas_upshift_promotors" /id="U2675" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.985014985014985" /psig="0.001998001998002" /xcortree=75 /SigmaFactorBS="catgttagcatctgttaaatcgttaaccgctactacctCAAC ttcaggattgtttaatGCTgcgcggaatacgttacgtccaatacgaccaaaaccgtta a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3348244 /Source="Nicolas_upshifts" /id="U2675" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.985014985014985" /psig="0.001998001998002" /xcortree=75 /SigmaFactorBS="catgttagcatctgttaaatcgttaaccgctactacctCAAC ttcaggattgtttaatGCTgcgcggaatacgttacgtccaatacgaccaaaaccgtta a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" CDS complement(3348350..3349372) /gene="cggR" /locus_tag="BSU_33950" /old_locus_tag="BSU33950" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:11489127, 12622823, 17142398, 17293407, 18052209, 18554327" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11489127, 12622823, 17142398, 17293407, 18052209, 18554327; Product type r : regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator of gapA" /protein_id="NP_391275.1" /db_xref="EnsemblGenomes-Gn:BSU33950" /db_xref="EnsemblGenomes-Tr:CAB15400" /db_xref="GOA:O32253" /db_xref="InterPro:IPR007324" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="PDB:2OKG" /db_xref="PDB:3BXE" /db_xref="PDB:3BXF" /db_xref="PDB:3BXG" /db_xref="PDB:3BXH" /db_xref="SubtiList:BG14085" /db_xref="UniProtKB/Swiss-Prot:O32253" /translation="MNQLIQAQKKLLPDLLLVMQKRFEILQYIRLTEPIGRRSLSASL GISERVLRGEVQFLKEQNLVDIKTNGMTLTEEGYELLSVLEDTMKDVLGLTLLEKTLK ERLNLKDAIIVSGDSDQSPWVKKEMGRAAVACMKKRFSGKNIVAVTGGTTIEAVAEMM TPDSKNRELLFVPARGGLGEDVKNQANTICAHMAEKASGTYRLLFVPGQLSQGAYSSI IEEPSVKEVLNTIKSASMLVHGIGEAKTMAQRRNTPLEDLKKIDDNDAVTEAFGYYFN ADGEVVHKVHSVGMQLDDIDAIPDIIAVAGGSSKAEAIEAYFKKPRNTVLVTDEGAAK KLLRDE*" gene complement(3348350..3349372) /gene="cggR" /locus_tag="BSU_33950" /old_locus_tag="BSU33950" upshifts complement(3348366) /Source="Nicolas_upshifts" /id="U2676" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.313686313686314" /psig="0.135864135864136" /xcortree=2684 /SigmaFactorBS="cttactttaaaaagccacgcaacacggttctCGtcacagacg aaggagccgcAaagaagttattaagggatgaataatccctcaatataaatatctctca c" /listShort="gapA, S1301, S1300, pgk, tpiA, pgm, eno" /GFF_Attribute="listLong" promotor_-10 complement(3348374) /Source="Nicolas_upshift_promotors" /id="U2676" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.313686313686314" /psig="0.135864135864136" /xcortree=2684 /SigmaFactorBS="cttactttaaaaagccacgcaacacggttctCGtcacagacg aaggagccgcAaagaagttattaagggatgaataatccctcaatataaatatctctca c" /listShort="gapA, S1301, S1300, pgk, tpiA, pgm, eno" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 complement(3348394..3348395) /Source="Nicolas_upshift_promotors" /id="U2676" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.313686313686314" /psig="0.135864135864136" /xcortree=2684 /SigmaFactorBS="cttactttaaaaagccacgcaacacggttctCGtcacagacg aaggagccgcAaagaagttattaagggatgaataatccctcaatataaatatctctca c" /listShort="gapA, S1301, S1300, pgk, tpiA, pgm, eno" /GFF_Attribute="listLong" /label="promotor_-35" S_feature complement(3349373..3349484) /Source="Nicolas_S_feature" /locus_tag="new_3483775_3483886_c" /HighExp="LPhT, C90, LBGtran, Heat, BI, LBGexp, Lbstat, Sw, Lbexp, G180" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigK" /TUshortPSig="0.993, 0.902" /TUlongSig="NA" /TUlongPSig="NA" /label="S1302" downshifts 3349410 /Source="Nicolas_upshifts" /id="D1765" /incds=0 /nref=3 /ntot=50 /MaxReadThrough="4.48989" /MaxDrop="5.24842" /score="-9.71393179" /energy="-11.8" /TU="NA" /idTUdmin="U2675" /TUdmin=1078 /isTUend="FALSE" promotor_-10 complement(3349465..3349484) /Source="Nicolas_upshift_promotors" /id="U2677" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.561438561438561" /psig="0.993006993006993" /xcortree=5 /SigmaFactorBS="tgaaaactctgcgaatattgtcgatgaattggctcttaaCAG TTGAAtaaacaattccacCCTGTTAAAATAATTAAAGAaagcagaaatgatttttttt g" /listShort="S1302, cggR, gapA, S1301, S1300, pgk, tpiA, pgm, eno" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3349484) /Source="Nicolas_upshifts" /id="U2677" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.561438561438561" /psig="0.993006993006993" /xcortree=5 /SigmaFactorBS="tgaaaactctgcgaatattgtcgatgaattggctcttaaCAG TTGAAtaaacaattccacCCTGTTAAAATAATTAAAGAaagcagaaatgatttttttt g" /listShort="S1302, cggR, gapA, S1301, S1300, pgk, tpiA, pgm, eno" /GFF_Attribute="listLong" S_feature complement(3349486..3349596) /Source="Nicolas_S_feature" /locus_tag="new_3483888_3483998_c" /HighExp="S8, S6, S7, BT, B36, S5, S4, S3, B60, G/S" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigK" /TUshortPSig="0.902" /TUlongSig="NA" /TUlongPSig="NA" /label="S1303" promotor_-35 complement(3349498..3349505) /Source="Nicolas_upshift_promotors" /id="U2677" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.561438561438561" /psig="0.993006993006993" /xcortree=5 /SigmaFactorBS="tgaaaactctgcgaatattgtcgatgaattggctcttaaCAG TTGAAtaaacaattccacCCTGTTAAAATAATTAAAGAaagcagaaatgatttttttt g" /listShort="S1302, cggR, gapA, S1301, S1300, pgk, tpiA, pgm, eno" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(3349579..3349598) /Source="Nicolas_upshift_promotors" /id="U2678" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.902097902097902" /psig="0.902097902097902" /xcortree=1316 /SigmaFactorBS="acagccctttctacgggaagggctgtttatattgGGATGCAC CAtttggcgctttcTGTATAAGATAAAGATATATaggataaaatattgctggataaaa c" /listShort="S1303, S1302, cggR, gapA, S1301, S1300" /listLong="pgk, tpiA, pgm, eno" /label="promotor_-10" upshifts complement(3349594) /Source="Nicolas_upshifts" /id="U2678" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.902097902097902" /psig="0.902097902097902" /xcortree=1316 /SigmaFactorBS="acagccctttctacgggaagggctgtttatattgGGATGCAC CAtttggcgctttcTGTATAAGATAAAGATATATaggataaaatattgctggataaaa c" /listShort="S1303, S1302, cggR, gapA, S1301, S1300" /listLong="pgk, tpiA, pgm, eno" promotor_-35 complement(3349611..3349620) /Source="Nicolas_upshift_promotors" /id="U2678" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.902097902097902" /psig="0.902097902097902" /xcortree=1316 /SigmaFactorBS="acagccctttctacgggaagggctgtttatattgGGATGCAC CAtttggcgctttcTGTATAAGATAAAGATATATaggataaaatattgctggataaaa c" /listShort="S1303, S1302, cggR, gapA, S1301, S1300" /listLong="pgk, tpiA, pgm, eno" /label="promotor_-35" CDS complement(3349670..3351064) /gene="araE" /locus_tag="BSU_33960" /old_locus_tag="BSU33960" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:9620981, 10417639, 15849754, 16850406, 20693325" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9620981, 10417639, 15849754, 16850406, 20693325; Product type t : transporter" /codon_start=1 /transl_table=11 /product="arabinose-related compounds permease" /protein_id="NP_391276.1" /db_xref="EnsemblGenomes-Gn:BSU33960" /db_xref="EnsemblGenomes-Tr:CAB15401" /db_xref="GOA:P96710" /db_xref="InterPro:IPR003663" /db_xref="InterPro:IPR005828" /db_xref="InterPro:IPR005829" /db_xref="InterPro:IPR020846" /db_xref="InterPro:IPR036259" /db_xref="SubtiList:BG11907" /db_xref="UniProtKB/Swiss-Prot:P96710" /translation="MKNTPTQLEPNVPVTRSHSMGFVILISCAAGLGGLLYGYDTAVI SGAIGFLKDLYSLSPFMEGLVISSIMIGGVVGVGISGFLSDRFGRRKILMTAALLFAI SAIVSALSQDVSTLIIARIIGGLGIGMGSSLSVTYITEAAPPAIRGSLSSLYQLFTIL GISATYFINLAVQRSGTYEWGVHTGWRWMLAYGMVPSVIFFLVLLVVPESPRWLAKAG KTNEALKILTRINGETVAKEELKNIENSLKIEQMGSLSQLFKPGLRKALVIGILLALF NQVIGMNAITYYGPEIFKMMGFGQNAGFVTTCIVGVVEVIFTVIAVLLIDKVGRKKLM SIGSAFMAIFMILIGTSFYFELTSGIMMIVLILGFVAAFCVSVGPITWIMISEIFPNH LRARAAGIATIFLWGANWAIGQFVPMMIDSFGLAYTFWIFAVINILCFLFVVTICPET KNKSLEEIEKLWIK*" gene complement(3349670..3351064) /gene="araE" /locus_tag="BSU_33960" /old_locus_tag="BSU33960" downshifts complement(3349684) /Source="Nicolas_upshifts" /id="D1766" /incds=0 /nref=1 /ntot=23 /MaxReadThrough="1.15614" /MaxDrop="3.28809" /score="1.06999853" /energy="-14.6" /TU="NA" /idTUdmin="U2679" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(3351163..3351182) /Source="Nicolas_upshift_promotors" /id="U2679" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.992007992007992" /psig="0.999000999001" /xcortree=348 /SigmaFactorBS="tttcagtatatcacagcgttctttgtaagaaaaCATTGACAg aaaatgcaaacaaGATTATTCTATATTTGTACGtactaattaaatgtaattttcgtta a" /listShort="araE" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3351177) /Source="Nicolas_upshifts" /id="U2679" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.992007992007992" /psig="0.999000999001" /xcortree=348 /SigmaFactorBS="tttcagtatatcacagcgttctttgtaagaaaaCATTGACAg aaaatgcaaacaaGATTATTCTATATTTGTACGtactaattaaatgtaattttcgtta a" /listShort="araE" /GFF_Attribute="listLong" promotor_-35 complement(3351197..3351204) /Source="Nicolas_upshift_promotors" /id="U2679" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.992007992007992" /psig="0.999000999001" /xcortree=348 /SigmaFactorBS="tttcagtatatcacagcgttctttgtaagaaaaCATTGACAg aaaatgcaaacaaGATTATTCTATATTTGTACGtactaattaaatgtaattttcgtta a" /listShort="araE" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 3351204..3351211 /Source="Nicolas_upshift_promotors" /id="U2680" /multdbtbs="SigA" /comp="M17" /sig="SigA" /pcomp="0.47052947052947" /psig=1 /xcortree=2310 /SigmaFactorBS="tatagaataatcttgtttgcattttctgtcaatGTTTTCTTa caaagaacgctgTGATATACTGAAATTTGTCCgtatacattttggaggaatggatatg t" /listShort="araR" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3351225..3351244 /Source="Nicolas_upshift_promotors" /id="U2680" /multdbtbs="SigA" /comp="M17" /sig="SigA" /pcomp="0.47052947052947" /psig=1 /xcortree=2310 /SigmaFactorBS="tatagaataatcttgtttgcattttctgtcaatGTTTTCTTa caaagaacgctgTGATATACTGAAATTTGTCCgtatacattttggaggaatggatatg t" /listShort="araR" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3351231 /Source="Nicolas_upshifts" /id="U2680" /multdbtbs="SigA" /comp="M17" /sig="SigA" /pcomp="0.47052947052947" /psig=1 /xcortree=2310 /SigmaFactorBS="tatagaataatcttgtttgcattttctgtcaatGTTTTCTTa caaagaacgctgTGATATACTGAAATTTGTCCgtatacattttggaggaatggatatg t" /listShort="araR" /GFF_Attribute="listLong" CDS 3351268..3352356 /gene="araR" /locus_tag="BSU_33970" /old_locus_tag="BSU33970" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:10417639, 11418559, 12949161, 14973026, 16585763, 17617643, 22281747, 26735940" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10417639, 11418559, 12949161, 14973026, 16585763, 17617643, 22281747, 26735940; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional repressor of the ara regulon (LacI family)" /protein_id="NP_391277.2" /db_xref="EnsemblGenomes-Gn:BSU33970" /db_xref="EnsemblGenomes-Tr:CAB15402" /db_xref="GOA:P96711" /db_xref="InterPro:IPR000524" /db_xref="InterPro:IPR028082" /db_xref="InterPro:IPR033532" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="PDB:3TB6" /db_xref="PDB:4EGY" /db_xref="PDB:4EGZ" /db_xref="PDB:4H0E" /db_xref="PDB:5D4R" /db_xref="PDB:5D4S" /db_xref="SubtiList:BG11913" /db_xref="UniProtKB/Swiss-Prot:P96711" /translation="MLPKYAQVKEEISSWINQGKILPDQKIPTENELMQQFGVSRHTI RKAIGDLVSQGLLYSVQGGGTFVASRSAKSALHSNKTIGVLTTYISDYIFPSIIRGIE SYLSEQGYSMLLTSTNNNPDNERRGLENLLSQHIDGLIVEPTKSALQTPNIGYYLNLE KNGIPFAMINASYAELAAPSFTLDDVKGGMMAAEHLLSLGHTHMMGIFKADDTQGVKR MNGFIQAHRERELFPSPDMIVTFTTEEKESKLLEKVKATLEKNSKHMPTAILCYNDEI ALKVIDMLREMDLKVPEDMSIVGYDDSHFAQISEVKLTSVKHPKSVLGKAAAKYVIDC LEHKKPKQEDVIFEPELIIRQSARKLNE*" gene 3351268..3352356 /gene="araR" /locus_tag="BSU_33970" /old_locus_tag="BSU33970" downshifts 3352336 /Source="Nicolas_upshifts" /id="D1767" /incds=0 /nref=202 /ntot=247 /MaxReadThrough="1.17419" /MaxDrop="4.76041" /score="20.2322165" /energy="-13.6" /TU="NA" /idTUdmin="U2680" /TUdmin=0 /isTUend="TRUE" CDS complement(3352405..3353415) /gene="yvbT" /locus_tag="BSU_33980" /old_locus_tag="BSU33980" /function="16.8: Protect" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 9836433; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative alkanal monooxygenase" /protein_id="NP_391278.1" /db_xref="EnsemblGenomes-Gn:BSU33980" /db_xref="EnsemblGenomes-Tr:CAB15403" /db_xref="GOA:O32254" /db_xref="InterPro:IPR011251" /db_xref="InterPro:IPR019949" /db_xref="InterPro:IPR036661" /db_xref="SubtiList:BG14086" /db_xref="UniProtKB/Swiss-Prot:O32254" /translation="MSNNQRKDTLLSVLNLSPVVQGGTIAESFRNSMDLARRAEEWGY HRYWLAEHHNIEGVASSATAVLIGHIAGGTKKIRVGSGGIMLPNHSSLVIAEQFGTLE TLYPGRIDLGLGRAPGTDQLTARALRRNINSGEDFPEQLEELRNYFKPSGNVRNQVRA IPGEGIDVPIWLLGSSGFSARLAGELGLPFAFAAHFSPANTVPALELYRNSFTPSDVL DEPYAMVGVTIIAADTNEKAQHLATSHYQRFLDLVRGTPNQLKPPVEDMDQIWSPYEK AMVNEQLSSTIVGGPEEVKAKLEDFVKTTQADEIMVNSETFEHADRMRSFEIIADVWK NR*" gene complement(3352405..3353415) /gene="yvbT" /locus_tag="BSU_33980" /old_locus_tag="BSU33980" downshifts complement(3352412) /Source="Nicolas_upshifts" /id="D1768" /incds=0 /nref=200 /ntot=252 /MaxReadThrough="1.53983" /MaxDrop="7.63266" /score="27.2032847" /energy="-14.2" /TU="NA" /idTUdmin="U2681" /TUdmin=0 /isTUend="TRUE" S_feature complement(3353416..3353493) /Source="Nicolas_S_feature" /locus_tag="new_3487818_3487895_c" /HighExp="dia5, dia15, Diami, H2O2, Salt, Paraq, G180, Etha, G150, G135" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="SigA" /TUlongPSig=1 /label="S1304" promotor_-10 complement(3353483..3353502) /Source="Nicolas_upshift_promotors" /id="U2681" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.912087912087912" /psig=1 /xcortree=2040 /SigmaFactorBS="ttatattgttcgaatttcatcgaatcaaatTCTTTTATtcct gaatgcagtTGTGTTATGGTGTGATAGAAgttctttcaatcatgacctgacagctttg g" /listShort="S1304, yvbT" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3353493) /Source="Nicolas_upshifts" /id="U2681" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.912087912087912" /psig=1 /xcortree=2040 /SigmaFactorBS="ttatattgttcgaatttcatcgaatcaaatTCTTTTATtcct gaatgcagtTGTGTTATGGTGTGATAGAAgttctttcaatcatgacctgacagctttg g" /listShort="S1304, yvbT" /GFF_Attribute="listLong" promotor_-35 complement(3353516..3353523) /Source="Nicolas_upshift_promotors" /id="U2681" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.912087912087912" /psig=1 /xcortree=2040 /SigmaFactorBS="ttatattgttcgaatttcatcgaatcaaatTCTTTTATtcct gaatgcagtTGTGTTATGGTGTGATAGAAgttctttcaatcatgacctgacagctttg g" /listShort="S1304, yvbT" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3353572..3354450) /gene="yvbU" /locus_tag="BSU_33990" /old_locus_tag="BSU33990" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative transcriptional regulator (LysR family)" /protein_id="NP_391279.1" /db_xref="EnsemblGenomes-Gn:BSU33990" /db_xref="EnsemblGenomes-Tr:CAB15404" /db_xref="GOA:O32255" /db_xref="InterPro:IPR000847" /db_xref="InterPro:IPR005119" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG14087" /db_xref="UniProtKB/Swiss-Prot:O32255" /translation="MTITQLKVFVKIAETGSFTKAGQALNMTQPAVSHAISAIEAELD VKLIIRDRRNGLMLTDTGKQILVHIREVLKGIEKVEQVAAAEKGLELGTIHIGTFSTA SAYFMPKLISEFKQKYPKLELVLHEGTVNEVKEWLHTRMIDVGILLYPTEEMEYIHLK KDKMAVVLRDDHPLASHSAITLKDLDHEPMIVCDGGYESPFIDMFRQAGATLHPAFTV YNINTSISMIREGLGLAILSEMSMSGMPLPEHVVTRELDPQVYRDVQLAVPSLKEASL AAKLFIEMAKELFGAE*" gene complement(3353572..3354450) /gene="yvbU" /locus_tag="BSU_33990" /old_locus_tag="BSU33990" promotor_-35 3354108..3354114 /Source="Nicolas_upshift_promotors" /id="U2682" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.72927072927073" /psig="0.72927072927073" /xcortree=1209 /SigmaFactorBS="acgagctcaagtttcggatatttttgttTAAATTCactgatc agcttcgGCATAAAATAAGccgaggcagttgagaatgtgccgatatggatcgttccca g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3354129..3354140 /Source="Nicolas_upshift_promotors" /id="U2682" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.72927072927073" /psig="0.72927072927073" /xcortree=1209 /SigmaFactorBS="acgagctcaagtttcggatatttttgttTAAATTCactgatc agcttcgGCATAAAATAAGccgaggcagttgagaatgtgccgatatggatcgttccca g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3354140 /Source="Nicolas_upshifts" /id="U2682" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.72927072927073" /psig="0.72927072927073" /xcortree=1209 /SigmaFactorBS="acgagctcaagtttcggatatttttgttTAAATTCactgatc agcttcgGCATAAAATAAGccgaggcagttgagaatgtgccgatatggatcgttccca g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 3354484..3354491 /Source="Nicolas_upshift_promotors" /id="U2684" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.98901098901099" /psig=1 /xcortree=2018 /SigmaFactorBS="tcataacaatttacttatgctccttataaaaaagattCATTT TATttatcttatgttcTACCGTATCATATGATGGAAaagttctacaaggagtgaatga a" /listShort="cyeB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(3354497..3354516) /Source="Nicolas_upshift_promotors" /id="U2683" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.732267732267732" /psig=1 /xcortree=1895 /SigmaFactorBS="ggagctgcttcattgttcattcactcctTGTAGaacttttcc atcaTATGATACGGTAGAACATAAgataaataaaatgaatcttttttataaggagcat a" /listShort="yvbU" /listLong="S1304, yvbT" /label="promotor_-10" upshifts complement(3354502) /Source="Nicolas_upshifts" /id="U2683" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.732267732267732" /psig=1 /xcortree=1895 /SigmaFactorBS="ggagctgcttcattgttcattcactcctTGTAGaacttttcc atcaTATGATACGGTAGAACATAAgataaataaaatgaatcttttttataaggagcat a" /listShort="yvbU" /listLong="S1304, yvbT" promotor_-10 3354505..3354524 /Source="Nicolas_upshift_promotors" /id="U2684" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.98901098901099" /psig=1 /xcortree=2018 /SigmaFactorBS="tcataacaatttacttatgctccttataaaaaagattCATTT TATttatcttatgttcTACCGTATCATATGATGGAAaagttctacaaggagtgaatga a" /listShort="cyeB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3354507 /Source="Nicolas_upshifts" /id="U2684" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.98901098901099" /psig=1 /xcortree=2018 /SigmaFactorBS="tcataacaatttacttatgctccttataaaaaagattCATTT TATttatcttatgttcTACCGTATCATATGATGGAAaagttctacaaggagtgaatga a" /listShort="cyeB" /GFF_Attribute="listLong" promotor_-35 complement(3354530..3354534) /Source="Nicolas_upshift_promotors" /id="U2683" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.732267732267732" /psig=1 /xcortree=1895 /SigmaFactorBS="ggagctgcttcattgttcattcactcctTGTAGaacttttcc atcaTATGATACGGTAGAACATAAgataaataaaatgaatcttttttataaggagcat a" /listShort="yvbU" /listLong="S1304, yvbT" /label="promotor_-35" CDS 3354550..3355467 /gene="cyeB" /locus_tag="BSU_34000" /old_locus_tag="BSU34000" /function="16.1: Circulate" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 10844694, 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="cysteine and O-acetylserine efflux permease" /protein_id="NP_391280.1" /db_xref="EnsemblGenomes-Gn:BSU34000" /db_xref="EnsemblGenomes-Tr:CAB15405" /db_xref="GOA:O32256" /db_xref="InterPro:IPR000620" /db_xref="SubtiList:BG14088" /db_xref="UniProtKB/Swiss-Prot:O32256" /translation="MKQLPKTRTALLLAFLVIMWGVNWPLSKAALAYSPPLLFAGIRT LIGGLLLVIVALPRIHKLRLKETWPIYLVSALLNITLFYGLQTIGLNYLPAGLFSAIV FFQPVLMGVFSWLWLGESMFVMKVIGLILGFAGVAVISAAGFGGHISVIGVLLALGSA VSWALGTVYMKKTGSRVDSIWMVALQLTIGSVFLLISGFWTESFSAIQWTAPFITSLL FISVFVIALGWLVFFTLVGSGEASKVASYTFLIPLISIVASSIFLHEPLTLSLLAGLL LIVTSICLVNTKSKAQKAAAIGINEKAAQ*" gene 3354550..3355467 /gene="cyeB" /locus_tag="BSU_34000" /old_locus_tag="BSU34000" downshifts 3355456 /Source="Nicolas_upshifts" /id="D1769" /incds=0 /nref=6 /ntot=15 /MaxReadThrough="2.97475" /MaxDrop="3.548" /score="22.9557936" /energy="-19.2" /TU="NA" /idTUdmin="U2684" /TUdmin="-4" /isTUend="TRUE" CDS complement(3355508..3356851) /gene="yvbW" /locus_tag="BSU_34010" /old_locus_tag="BSU34010" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406, 19258532, 25645558; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative leucine permease" /protein_id="NP_391281.1" /db_xref="EnsemblGenomes-Gn:BSU34010" /db_xref="EnsemblGenomes-Tr:CAB15406" /db_xref="GOA:O32257" /db_xref="InterPro:IPR002293" /db_xref="InterPro:IPR004841" /db_xref="SubtiList:BG14089" /db_xref="UniProtKB/Swiss-Prot:O32257" /translation="MKNDNQTLKRTMTSRHIMMMALGGAIGAGLFKGSSSAIDVAGPS VIIAYLLGGIILLFIMQGLAEMAVRNRNARTFRDLVQQVLGNYAAYFLDWIYWKMWVL NIAAEAVVAAIFIQYWLPGCPIWVLALGISLIVTIVNLLSVKIFAETEYWLAMIKITV IIIFIILGLLLLFVSFGDHTASGFSNLTDHGGFFPHGGTGLITAMLVVIYSYGGTEII GVTLAETKNPEKVVPKAVRSTLTRIVAFYLLPFFIIVSLIPWNQVNSVPESPFVMVFK MVGIPGADHIMNAVILLAIISSMNSGLYGSSRILYTQASDGRLPKVFSKLSSKNVPMF AILMCTSSLYIGVLISLFAGSQTFNYLMGSLGYTVLFIWLIIGFAHLKSRKQQTETPA YYVKWFPYTTWFAIVALLAILIGVIMTTSIVITGITAAIYLLITVAYLVKGRKHQ*" gene complement(3355508..3356851) /gene="yvbW" /locus_tag="BSU_34010" /old_locus_tag="BSU34010" misc_RNA complement(3356920..3357155) /gene="tboX" /locus_tag="BSU_misc_RNA_56" /product="T-box riboswitch controlling synthesis of an amino acid transporter" /note="Evidence 2b: Function from indirect experimental evidences (e.g. phenotypes); PubMedId: 18625071, 19258532; Product type n: RNA" /function="16.3: Control" gene complement(3356920..3357155) /gene="tboX" /locus_tag="BSU_misc_RNA_56" downshifts complement(3357054) /Source="Nicolas_upshifts" /id="D1770" /incds=1 /nref=1 /ntot=104 /MaxReadThrough="5.18182" /MaxDrop="2.29735" /score="33.4262209" /energy="-24.4" /TU="U2685,U2689" /idTUdmin="U2689" /TUdmin="-66" /isTUend="FALSE" S_feature complement(3357156..3357252) /Source="Nicolas_S_feature" /locus_tag="new_3491558_3491654_c" /HighExp="Cold, GM 120, C30, GM 90, C90, GM 15, GM 10, GM 25, HPh, GM 60" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigD, SigA" /TUshortPSig="1, 0.994" /TUlongSig="SigA" /TUlongPSig=1 /label="S1305" CDS complement(3357253..3358287) /gene="yvbX" /locus_tag="BSU_34020" /old_locus_tag="BSU34020" /function="16.5: Explore" /function="16.13: Shape" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 12177332; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative epimerase modification of peptidoglycan" /protein_id="NP_391282.1" /db_xref="EnsemblGenomes-Gn:BSU34020" /db_xref="EnsemblGenomes-Tr:CAB15407" /db_xref="GOA:O32258" /db_xref="InterPro:IPR001223" /db_xref="InterPro:IPR011583" /db_xref="InterPro:IPR017853" /db_xref="SubtiList:BG14090" /db_xref="UniProtKB/Swiss-Prot:O32258" /translation="MKKWLIIAVSLAIAIVLFMYTKGEAKAAGMTVGYTTGDTASYNS LTKYHTYMNAIATDTFAFEKNGQIIGDAPTKQLTYAKKKKIKTWAVISNYNDAIYDFD GDLASRVMSNKTAKKRFTDQLITLAKKHSYYGINIDFEAVNPEDRAAYSNFIQYVSQA LNKKHIKTMVSVPAKSADDKNDDWSWPYDYAKIGKYADFVQVMTYDEHGIWGEPGSVA STNWIKSSLQFSVKKIKANKVIMGIPAYGYDWDVKDGSTSTIREWNELKSLIKKQKAK PAFNKKSGSMTFSYVDKKKHKHVVWYENEKTVQTKSHLAKQYKIAGVSVYALGNESES FWKAIRKGTK*" gene complement(3357253..3358287) /gene="yvbX" /locus_tag="BSU_34020" /old_locus_tag="BSU34020" promotor_-10 complement(3358309..3358327) /Source="Nicolas_upshift_promotors" /id="U2685" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2815 /SigmaFactorBS="catatgccgggctttttgcttgaaaaaaCTTCAACTtccaat tttttgGCCGATGAGAAGAGTATGActtgatacaggaggaaatgcgatgaaaaaatgg c" /listShort="yvbX, S1305, NA, yvbW" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3358315) /Source="Nicolas_upshifts" /id="U2685" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2815 /SigmaFactorBS="catatgccgggctttttgcttgaaaaaaCTTCAACTtccaat tttttgGCCGATGAGAAGAGTATGActtgatacaggaggaaatgcgatgaaaaaatgg c" /listShort="yvbX, S1305, NA, yvbW" /GFF_Attribute="listLong" promotor_-35 complement(3358340..3358347) /Source="Nicolas_upshift_promotors" /id="U2685" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2815 /SigmaFactorBS="catatgccgggctttttgcttgaaaaaaCTTCAACTtccaat tttttgGCCGATGAGAAGAGTATGActtgatacaggaggaaatgcgatgaaaaaatgg c" /listShort="yvbX, S1305, NA, yvbW" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3358395..3359117) /gene="lutC" /locus_tag="BSU_34030" /old_locus_tag="BSU34030" /function="16.6: Maintain" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:22427629, 24196425, 24274019" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 22427629, 24196425, 24274019; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="component of an iron-sulfur oxidase for L-lactate utilization" /protein_id="NP_391283.1" /db_xref="EnsemblGenomes-Gn:BSU34030" /db_xref="EnsemblGenomes-Tr:CAB15408" /db_xref="InterPro:IPR003741" /db_xref="InterPro:IPR022823" /db_xref="SubtiList:BG14091" /db_xref="UniProtKB/Swiss-Prot:O32259" /translation="MTKGTIQNQESFLNRIASSLGRERRTGGVAVPEWAHQPQYKTLE GYSADDLVTVLKNHCVKIHTELIETDSTGLYDALREQVSRFSGGPVIIPKDPRFEEYG LKSLLTKDWPSEGTPVWEWDADKGEENIKKAEQANVGITFSEITLAESGTVVLFSSKD IGRSVSLLPTTYIAIVPKSSIVPRMTQASDIIRQNIANGVTVPSCINYITGPSNSADI EMDLVVGVHGPVKAAYILVSDR*" gene complement(3358395..3359117) /gene="lutC" /locus_tag="BSU_34030" /old_locus_tag="BSU34030" downshifts complement(3358411) /Source="Nicolas_upshifts" /id="D1771" /incds=0 /nref=194 /ntot=266 /MaxReadThrough="4.5919" /MaxDrop="7.41457" /score="25.5917046" /energy="-15.7" /TU="U2689" /idTUdmin="U2689" /TUdmin="-1423" /isTUend="FALSE" CDS complement(3359117..3360556) /gene="lutB" /locus_tag="BSU_34040" /old_locus_tag="BSU34040" /function="16.6: Maintain" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:16513748, 19201793, 19508281, 22427629, 24196425, 24274019, 28032445" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16513748, 19201793, 19508281, 22427629, 24196425, 24274019, 28032445; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="component of an iron-sulfur oxidase linked to L-lactate utilization" /protein_id="NP_391284.1" /db_xref="EnsemblGenomes-Gn:BSU34040" /db_xref="EnsemblGenomes-Tr:CAB15409" /db_xref="GOA:O07021" /db_xref="InterPro:IPR003741" /db_xref="InterPro:IPR004452" /db_xref="InterPro:IPR009051" /db_xref="InterPro:IPR017896" /db_xref="InterPro:IPR017900" /db_xref="InterPro:IPR022825" /db_xref="InterPro:IPR024569" /db_xref="SubtiList:BG12448" /db_xref="UniProtKB/Swiss-Prot:O07021" /translation="MAMKIGTDAFKERVSQGIDNEFMRGAVSGAQERLRTRRLEAAEE LGNWEEWRSLSEEIRQHVLENLDFYLGQLAENVAKRGGHVYFAKTAEEASSYIRDVIQ KKNGKKIVKSKSMVTEEINLNEVLEKEGCEVVETDLGEYILQIDDHDPPSHIVAPALH KNKEQIRDVFKERLDYQHTEKPEELVMHARAILRKKFLEADIGITGCNFAIADTGSVS LVTNEGNGRLVSTLPKTQITVMGMERIVPSFSEFEVLVSMLTRSAVGQRLTSYITALT GPKLEGEVDGPEEFHLVIVDNGRSNILGTEFQSVLQCIRCAACINVCPVYRHVGGHSY GSIYSGPIGAVLSPLLGGYDDYKELPYASSLCAACSEACPVKIPLHELLLKHRQNIVE KEGRAPISEKLAMKAFGLGASSLSLYKMGSKWAPAAMTPFTEDEKISKGPGPLKNWTQ IRDFPAPHKSRFRDWFADRETSERTKEEQ*" gene complement(3359117..3360556) /gene="lutB" /locus_tag="BSU_34040" /old_locus_tag="BSU34040" promotor_-35 3360104..3360107 /Source="Nicolas_upshift_promotors" /id="U2686" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.967032967032967" /psig="0.001998001998002" /xcortree=71 /SigmaFactorBS="gctctttatttttatgaagagcgggcgctacgatatgtgaCG GCggatcgtgatcatcaatCTGCAaaatatactcgccgagatcggtttctacgacttc a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 3360124 /Source="Nicolas_upshifts" /id="U2686" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.967032967032967" /psig="0.001998001998002" /xcortree=71 /SigmaFactorBS="gctctttatttttatgaagagcgggcgctacgatatgtgaCG GCggatcgtgatcatcaatCTGCAaaatatactcgccgagatcggtttctacgacttc a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 3360125..3360129 /Source="Nicolas_upshift_promotors" /id="U2686" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.967032967032967" /psig="0.001998001998002" /xcortree=71 /SigmaFactorBS="gctctttatttttatgaagagcgggcgctacgatatgtgaCG GCggatcgtgatcatcaatCTGCAaaatatactcgccgagatcggtttctacgacttc a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" downshifts 3360278 /Source="Nicolas_upshifts" /id="D1772" /incds=1 /nref=1 /ntot=175 /MaxReadThrough="1.77859" /MaxDrop="3.31917" /score="-7.50175872" /energy="-11.7" /TU="NA" /idTUdmin="U2686" /TUdmin=0 /isTUend="TRUE" upshifts 3360432 /Source="Nicolas_upshifts" /id="U2687" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.932067932067932" /psig="0.000999000999001" /xcortree=69 /SigmaFactorBS="acatgctgcctgatttcctctgataatgagcgccactcctcc cagtttcccagttcttctgCTgcctctaggcgccgcgtccgcagacgctcctgtgcac c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" misc_feature 3360433..3360434 /Source="Nicolas_upshift_promotors" /id="U2687" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.932067932067932" /psig="0.000999000999001" /xcortree=69 /SigmaFactorBS="acatgctgcctgatttcctctgataatgagcgccactcctcc cagtttcccagttcttctgCTgcctctaggcgccgcgtccgcagacgctcctgtgcac c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" CDS complement(3360583..3361299) /gene="lutA" /locus_tag="BSU_34050" /old_locus_tag="BSU34050" /EC_number="1.8.98.-" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:16513748, 19201793, 19508281, 22427629, 24196425, 24274019, 28032445" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16513748, 19201793, 19508281, 22427629, 24196425, 24274019, 28032445; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="iron-sulfur oxidase subunit used in L-lactate utilization" /protein_id="NP_391285.1" /db_xref="EnsemblGenomes-Gn:BSU34050" /db_xref="EnsemblGenomes-Tr:CAB15410" /db_xref="GOA:O07020" /db_xref="InterPro:IPR004017" /db_xref="InterPro:IPR022822" /db_xref="SubtiList:BG12447" /db_xref="UniProtKB/Swiss-Prot:O07020" /translation="MKVSLFVTCLVDMFQTNVGKATVELLERLGCEVDFPEGQICCGQ PAYNSGYVHDAKKAMKRMIETFQDSEYVVSPSGSCTTMFREYPHLFQDDPKWADKAKK LADKTYELTDFIVNVLGVEDVGATLHTKATLHTSCHMTRLLGVRKEPMKLLSHVKGLQ FTELPGKHNCCGFGGTFSVKMAQISEQMVDEKVECVEETGAEVLIGADCGCLMNIGGR LGRKDKNVKVMHIAEVLNSR*" gene complement(3360583..3361299) /gene="lutA" /locus_tag="BSU_34050" /old_locus_tag="BSU34050" promotor_-35 3361203..3361210 /Source="Nicolas_upshift_promotors" /id="U2688" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.982017982017982" /psig=0 /xcortree=72 /SigmaFactorBS="ccggctgtccgcagcaaatctgcccttctggaaaatcaaCCT CGCACccaagccgctccaGCAgctcaaccgttgcttttccgacatttgtttgaaacat a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3361224..3361226 /Source="Nicolas_upshift_promotors" /id="U2688" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.982017982017982" /psig=0 /xcortree=72 /SigmaFactorBS="ccggctgtccgcagcaaatctgcccttctggaaaatcaaCCT CGCACccaagccgctccaGCAgctcaaccgttgcttttccgacatttgtttgaaacat a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3361224 /Source="Nicolas_upshifts" /id="U2688" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.982017982017982" /psig=0 /xcortree=72 /SigmaFactorBS="ccggctgtccgcagcaaatctgcccttctggaaaatcaaCCT CGCACccaagccgctccaGCAgctcaaccgttgcttttccgacatttgtttgaaacat a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" downshifts 3361297 /Source="Nicolas_upshifts" /id="D1773" /incds=0 /nref=15 /ntot=169 /MaxReadThrough="1.96527" /MaxDrop="4.662" /score="-7.50175872" /energy="-11.7" /TU="NA" /idTUdmin="U2688" /TUdmin="-15" /isTUend="TRUE" S_feature complement(3361300..3361366) /Source="Nicolas_S_feature" /locus_tag="new_3495702_3495768_c" /HighExp="C90, M40t90, T3.0H, T4.0H, HiOs, T1.0H, T3.30H, T2.30H, Lbstat, Lbtran" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.994" /TUlongSig="SigA" /TUlongPSig=1 /label="S1306" promotor_-10 complement(3361363..3361382) /Source="Nicolas_upshift_promotors" /id="U2689" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.754245754245754" /psig="0.994005994005994" /xcortree=3211 /SigmaFactorBS="aaatgaaaatatccctagaaaaCTCTTTCCttccattgtcag aaTAGTGTACGATATTCATATAgttattttaactcaggtcatcagatgacctgatcat a" /listShort="S1306, yvfV, yvfW, yvbY, yvbX, S1305, NA" /listLong="yvbW" /label="promotor_-10" upshifts complement(3361366) /Source="Nicolas_upshifts" /id="U2689" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.754245754245754" /psig="0.994005994005994" /xcortree=3211 /SigmaFactorBS="aaatgaaaatatccctagaaaaCTCTTTCCttccattgtcag aaTAGTGTACGATATTCATATAgttattttaactcaggtcatcagatgacctgatcat a" /listShort="S1306, yvfV, yvfW, yvbY, yvbX, S1305, NA" /listLong="yvbW" promotor_-35 complement(3361397..3361404) /Source="Nicolas_upshift_promotors" /id="U2689" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.754245754245754" /psig="0.994005994005994" /xcortree=3211 /SigmaFactorBS="aaatgaaaatatccctagaaaaCTCTTTCCttccattgtcag aaTAGTGTACGATATTCATATAgttattttaactcaggtcatcagatgacctgatcat a" /listShort="S1306, yvfV, yvfW, yvbY, yvbX, S1305, NA" /listLong="yvbW" /label="promotor_-35" CDS complement(3361474..3362076) /gene="yvfU" /locus_tag="BSU_34060" /old_locus_tag="BSU34060" /function="16.12: Sense" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:11717295, 18925929, 23504016" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11717295, 18925929, 23504016; Product type r: regulator" /codon_start=1 /transl_table=11 /product="two-component response regulator [YvfT]" /protein_id="NP_391286.1" /db_xref="EnsemblGenomes-Gn:BSU34060" /db_xref="EnsemblGenomes-Tr:CAB15411" /db_xref="GOA:O07019" /db_xref="InterPro:IPR000792" /db_xref="InterPro:IPR001789" /db_xref="InterPro:IPR011006" /db_xref="InterPro:IPR016032" /db_xref="InterPro:IPR036388" /db_xref="SubtiList:BG12446" /db_xref="UniProtKB/Swiss-Prot:O07019" /translation="MIRLFIAEDQRMLLGALGSLLDLEEDMTVIGQALNGEEALHAIL KLEPDVCIMDIEMPVRSGLNVAEELMKKGCVSKVIILTTFARPGYFERAVKAGAHGYL LKDGEIDDLADAIRKCVKGKRVFSPELTFNMMRDENPLTVREQEILRLAALGKTTKDI TLELYLSQGTVRNYISEIIQKLNAKNRTEAASIAEEKGWI*" gene complement(3361474..3362076) /gene="yvfU" /locus_tag="BSU_34060" /old_locus_tag="BSU34060" CDS complement(3362093..3363208) /gene="yvfT" /locus_tag="BSU_34070" /old_locus_tag="BSU34070" /function="16.3: Control" /function="16.12: Sense" /experiment="publication(s) with functional evidences, PMID:11717295, 18925929, 23504016" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11717295, 18925929, 23504016; Product type rc: receptor" /codon_start=1 /transl_table=11 /product="two-component sensor histidine kinase [YvfU]" /protein_id="NP_391287.2" /db_xref="EnsemblGenomes-Gn:BSU34070" /db_xref="EnsemblGenomes-Tr:CAB15412" /db_xref="GOA:Q795K2" /db_xref="InterPro:IPR003594" /db_xref="InterPro:IPR011712" /db_xref="InterPro:IPR036890" /db_xref="SubtiList:BG12445" /db_xref="UniProtKB/Swiss-Prot:Q795K2" /translation="MKKAISIFPKEFGFFPYIFLVYTIMPFLSLLKESGVKQGIGYGM LLLFVAAYRQLFCSVGKASFTYWLIVQMAVILMYSVFYNITYIYLGFFPANFVGYYKE KTNFNRAFCALIFILLFPCLYQFIANSVSLRELFSVLPFLVIMLISPFGIRSMFRRIE LEAKLAQANEQIKELSKREERVRIARDLHDTLGHTLSLLTLKSQLIQRLAASDPERTK LEAKEMETSSRSALKQVRELVSDMRTVTITEELVNIQHILRAGNITFQYEGADDFSVI SPVTQNIISMCMREAVTNIIKHSKATHCAITISQFADKMRIVIRDDGKGAPKEKMFGN GLWGMEERLMLIEGGLTVSDHNGTVVALTIPLIKKAE*" gene complement(3362093..3363208) /gene="yvfT" /locus_tag="BSU_34070" /old_locus_tag="BSU34070" CDS complement(3363212..3363949) /gene="yvfS" /locus_tag="BSU_34080" /old_locus_tag="BSU34080" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 11717295, 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative ABC transporter (permease)" /protein_id="NP_391288.1" /db_xref="EnsemblGenomes-Gn:BSU34080" /db_xref="EnsemblGenomes-Tr:CAB15413" /db_xref="GOA:O07017" /db_xref="InterPro:IPR000412" /db_xref="SubtiList:BG12444" /db_xref="UniProtKB/Swiss-Prot:O07017" /translation="MNVLQKQSIAEMKRVLRNKYFVLWSLIMPIAFYYFFTNVVNTNV PDQRAWEAHYLMSMTVFSVMGSSIMTLGIRMVQERSQGWAAFIRLTPLPDHIYLSAQM IGQSVIHVLSITVIFLFGAIINDIALSPFEWMMSGLWILFGALPFLALGTLIGLMRKV ETAAGISNVLYMLLALGGGMWMPFEVMPDMMQSIGQWLPSYHFGSGAWELVRGGSPTW KNILILIAYMMLFMLLSKYIRRKQEAV*" gene complement(3363212..3363949) /gene="yvfS" /locus_tag="BSU_34080" /old_locus_tag="BSU34080" promotor_-10 complement(3363238..3363257) /Source="Nicolas_upshift_promotors" /id="U2690" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.978021978021978" /psig=1 /xcortree=3117 /SigmaFactorBS="gtgggagtccgacttggaaaaatattctgatattaaTCGCTT ATatgatgctcttCATGCTACTATCTAAATATAtaagaagaaaacaagaagcggtgta a" /listShort="yvfT, yvfU" /listLong="S1306, yvfV, yvfW, yvbY, yvbX, S1305, NA" /label="promotor_-10" upshifts complement(3363252) /Source="Nicolas_upshifts" /id="U2690" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.978021978021978" /psig=1 /xcortree=3117 /SigmaFactorBS="gtgggagtccgacttggaaaaatattctgatattaaTCGCTT ATatgatgctcttCATGCTACTATCTAAATATAtaagaagaaaacaagaagcggtgta a" /listShort="yvfT, yvfU" /listLong="S1306, yvfV, yvfW, yvbY, yvbX, S1305, NA" promotor_-35 complement(3363269..3363276) /Source="Nicolas_upshift_promotors" /id="U2690" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.978021978021978" /psig=1 /xcortree=3117 /SigmaFactorBS="gtgggagtccgacttggaaaaatattctgatattaaTCGCTT ATatgatgctcttCATGCTACTATCTAAATATAtaagaagaaaacaagaagcggtgta a" /listShort="yvfT, yvfU" /listLong="S1306, yvfV, yvfW, yvbY, yvbX, S1305, NA" /label="promotor_-35" CDS complement(3363950..3364855) /gene="yvfR" /locus_tag="BSU_34090" /old_locus_tag="BSU34090" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 11717295; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative ABC efflux transporter (ATP-binding protein)" /protein_id="NP_391289.1" /db_xref="EnsemblGenomes-Gn:BSU34090" /db_xref="EnsemblGenomes-Tr:CAB15414" /db_xref="GOA:O07016" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR017871" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG12443" /db_xref="UniProtKB/Swiss-Prot:O07016" /translation="MMKEAVTVSNVTKHFQRKTAVNNISFSIEKGEIAAILGPNGAGK TTVVSMILGLLKPSEGEIKLFNRVPDDQQVREKIGVMLQEVSVMPGLKVDEILELFRS YYPNPLSMKELVSLTALTKEDLKTRAEKLSGGQKRRLSFALALAGNPELLILDEPTVG MDTSSRHRFWQTIHGLSDQGKTIIFSTHYLQEADDAAQRILFFTEGQLVADGSPMQIR SRIQKQSVSFTLHSSESLERLSCHPEVERVIHEHERTIIQTSNTDKVLALIFQENIHA RDIRIEQATLDEAFRQLADGNREAM*" gene complement(3363950..3364855) /gene="yvfR" /locus_tag="BSU_34090" /old_locus_tag="BSU34090" promotor_-10 complement(3364875..3364893) /Source="Nicolas_upshift_promotors" /id="U2691" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.395604395604396" /psig="0.892107892107892" /xcortree=312 /SigmaFactorBS="gacatttgtcactccatcatcatgacaccccataCTAAcatc gtcttctccgtCATTTTACAATCAATGTAAacgatcaggaggtgctcatgtgatgaaa g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3364886) /Source="Nicolas_upshifts" /id="U2691" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.395604395604396" /psig="0.892107892107892" /xcortree=312 /SigmaFactorBS="gacatttgtcactccatcatcatgacaccccataCTAAcatc gtcttctccgtCATTTTACAATCAATGTAAacgatcaggaggtgctcatgtgatgaaa g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(3364909..3364912) /Source="Nicolas_upshift_promotors" /id="U2691" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.395604395604396" /psig="0.892107892107892" /xcortree=312 /SigmaFactorBS="gacatttgtcactccatcatcatgacaccccataCTAAcatc gtcttctccgtCATTTTACAATCAATGTAAacgatcaggaggtgctcatgtgatgaaa g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 3365064..3365071 /Source="Nicolas_upshift_promotors" /id="U2692" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.99100899100899" /psig=1 /xcortree=2247 /SigmaFactorBS="ttcttttaaactgctgtgacattcatagaaagataCACTCTT CaaaccatccgAGTGTTATGATAGAAATATTgaactttatattactttccggctgaaa g" /listShort="rsbQ, rsbP" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3365082..3365101 /Source="Nicolas_upshift_promotors" /id="U2692" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.99100899100899" /psig=1 /xcortree=2247 /SigmaFactorBS="ttcttttaaactgctgtgacattcatagaaagataCACTCTT CaaaccatccgAGTGTTATGATAGAAATATTgaactttatattactttccggctgaaa g" /listShort="rsbQ, rsbP" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3365089 /Source="Nicolas_upshifts" /id="U2692" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.99100899100899" /psig=1 /xcortree=2247 /SigmaFactorBS="ttcttttaaactgctgtgacattcatagaaagataCACTCTT CaaaccatccgAGTGTTATGATAGAAATATTgaactttatattactttccggctgaaa g" /listShort="rsbQ, rsbP" /GFF_Attribute="listLong" CDS 3365139..3365948 /gene="rsbQ" /locus_tag="BSU_34100" /old_locus_tag="BSU34100" /function="16.3: Control" /function="16.8: Protect" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:11591687, 12620626, 15632289, 21980452" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11591687, 12620626, 15632289, 21980452; Product type r: regulator" /codon_start=1 /transl_table=11 /product="regulator of RsbP phosphatase" /protein_id="NP_391290.1" /db_xref="EnsemblGenomes-Gn:BSU34100" /db_xref="EnsemblGenomes-Tr:CAB15415" /db_xref="InterPro:IPR000073" /db_xref="InterPro:IPR029058" /db_xref="InterPro:IPR031143" /db_xref="PDB:1WOM" /db_xref="PDB:1WPR" /db_xref="SubtiList:BG12442" /db_xref="UniProtKB/Swiss-Prot:O07015" /translation="MNEAILSRNHVKVKGSGKASIMFAPGFGCDQSVWNAVAPAFEED HRVILFDYVGSGHSDLRAYDLNRYQTLDGYAQDVLDVCEALDLKETVFVGHSVGALIG MLASIRRPELFSHLVMVGPSPCYLNDPPEYYGGFEEEQLLGLLEMMEKNYIGWATVFA ATVLNQPDRPEIKEELESRFCSTDPVIARQFAKAAFFSDHREDLSKVTVPSLILQCAD DIIAPATVGKYMHQHLPYSSLKQMEARGHCPHMSHPDETIQLIGDYLKAHV*" gene 3365139..3365948 /gene="rsbQ" /locus_tag="BSU_34100" /old_locus_tag="BSU34100" CDS 3365984..3367195 /gene="rsbP" /locus_tag="BSU_34110" /old_locus_tag="BSU34110" /EC_number="3.1.3.3" /function="16.8: Protect" /function="16.3: Control" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:10632888, 11591687, 15342585, 15632289, 16267279, 19948797, 21980452, 23524614" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10632888, 11591687, 15342585, 15632289, 16267279, 19948797, 21980452, 23524614; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="phosphoserine protein-phosphatase" /protein_id="NP_391291.1" /db_xref="EnsemblGenomes-Gn:BSU34110" /db_xref="EnsemblGenomes-Tr:CAB15416" /db_xref="GOA:O07014" /db_xref="InterPro:IPR000014" /db_xref="InterPro:IPR001932" /db_xref="InterPro:IPR035965" /db_xref="InterPro:IPR036457" /db_xref="SubtiList:BG12441" /db_xref="UniProtKB/Swiss-Prot:O07014" /translation="MDKQLNDAPCGFLALSEEGSIIAANRTLIKILDYEPEQVIGQHM NMMLTIPAQLFCQLYFFPLLKLEHHIEEIYISLKARDGEEIPVLINAIARHDSGASVF DCVLIPMRKRNEYENELLIARNEAQEALLAKQKANAELEIALETLKAKQEELLEINKQ NQQFKLNTKRELELARKIQKNSLTEPIVNDQVQIDSYYNASSELSGDLYGYYQIDEHR YGIIILDVMGHGISSALITMSLHPLFQRQITQGLSPVKVMKELDRHLHSLFQNDEEAR HYCTAIYLEIDIARQRIDYVNAGHPPALWQDDSGTQHLLHATSPPIGMFEDLEFQSSS LSYTEDGRLLLYTDGVMDPTASCYLFDLLKDHPDSPIADLKEKILTSLQHQKEAHHKS DDECFILVDVK*" gene 3365984..3367195 /gene="rsbP" /locus_tag="BSU_34110" /old_locus_tag="BSU34110" downshifts 3367182 /Source="Nicolas_upshifts" /id="D1774" /incds=0 /nref=181 /ntot=246 /MaxReadThrough="0.90827" /MaxDrop="5.41923" /score="26.3528321" /energy="-17.8" /TU="NA" /idTUdmin="U2692" /TUdmin="-4" /isTUend="TRUE" CDS complement(3367249..3368538) /gene="ganB" /locus_tag="BSU_34120" /old_locus_tag="BSU34120" /EC_number="3.2.1.-" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:11682178, 17056685, 27501980" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11682178, 17056685, 27501980; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="endo-beta-1,4-galactanase" /protein_id="NP_391292.2" /db_xref="EnsemblGenomes-Gn:BSU34120" /db_xref="EnsemblGenomes-Tr:CAB15417" /db_xref="GOA:O07013" /db_xref="InterPro:IPR011683" /db_xref="InterPro:IPR017853" /db_xref="SubtiList:BG12440" /db_xref="UniProtKB/Swiss-Prot:O07013" /translation="MKSKVKMFFAAAIVWSACSSTGYAAAIEKEKHVSELRAEDLFVK KVEGMNKDFIKGADVSSVIALENSGVTFYNTNGKRQDIFTTLKQAGVNYVRVRIWNHP YDSNGNGYGGGNNDVQKAIEIGKRATANGMKVLADFHYSDFWADPAKQKVPKAWANLS FEAKKAKLYEYTKQSLQKMIKEGVDIGMVQVGNETTGGFAGETDWTKMCQLFNEGSRA VRETNSNILVALHFTNPETAGRYSFIAETLSKNKVDYDVFASSYYPFWHGTLQNLTSV LKAVANTYGKKVMVAETSYTYTAEDGDGHGNTAPKSGQTLPYPISVQGQATAVRDVME AVANTGKAGLGVFYWEPAWIPVGPKTQIEKNKVLWETYGSGWASSYAAEYDPEDAGKW YGGSAVDNQALFDFNGHPLPSLQVFQYAESGHIPKKR*" gene complement(3367249..3368538) /gene="ganB" /locus_tag="BSU_34120" /old_locus_tag="BSU34120" CDS complement(3368618..3370681) /gene="ganA" /locus_tag="BSU_34130" /old_locus_tag="BSU34130" /EC_number="3.2.1.23" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:2104611, 9287030, 17056685, 27501980" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 2104611, 9287030, 17056685, 27501980; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="short chain beta-1,4-galacto-oligosaccharides beta-galactosidase (beta-galacto-pyranoside hydrolase)" /protein_id="NP_391293.1" /db_xref="EnsemblGenomes-Gn:BSU34130" /db_xref="EnsemblGenomes-Tr:CAB15418" /db_xref="GOA:O07012" /db_xref="InterPro:IPR003476" /db_xref="InterPro:IPR013529" /db_xref="InterPro:IPR013738" /db_xref="InterPro:IPR013739" /db_xref="InterPro:IPR017853" /db_xref="InterPro:IPR029062" /db_xref="SubtiList:BG12439" /db_xref="UniProtKB/Swiss-Prot:O07012" /translation="MMSKLEKTHVTKAKFMLHGGDYNPDQWLDRPDILADDIKLMKLS HTNTFSVGIFAWSALEPEEGVYQFEWLDDIFERIHSIGGRVILATPSGARPAWLSQTY PEVLRVNASRVKQLHGGRHNHCLTSKVYREKTRHINRLLAERYGHHPALLMWHISNEY GGDCHCDLCQHAFREWLKSKYDNSLKTLNHAWWTPFWSHTFNDWSQIESPSPIGENGL HGLNLDWRRFVTDQTISFYENEIIPLKELTPDIPITTNFMADTPDLIPYQGLDYSKFA KHVDAISWDAYPVWHNDWESTADLAMKVGFINDLYRSLKQQPFLLMECTPSAVNWHNV NKAKRPGMNLLSSMQMIAHGSDSVLYFQYRKSRGSSEKLHGAVVDHDNSPKNRVFQEV AKVGETLERLSEVVGTKRPAQTAILYDWENHWALEDAQGFAKATKRYPQTLQQHYRTF WEHDIPVDVITKEQDFSPYKLLIVPMLYLISEDTVSRLKAFTADGGTLVMTYISGVVN EHDLTYTGGWHPDLQAIFGVEPLETDTLYPKDRNAVSYRSQIYEMKDYATVIDVKTAS VEAVYQEDFYARTPAVTSHEYQQGKAYFIGARLEDQFQRDFYEGLITDLSLSPVFPVR HGKGVSVQARQDQDNDYIFVMNFTEEKQLVTFDQSVKDIMTGDILSGDLTMEKYEVRI VVNTH*" gene complement(3368618..3370681) /gene="ganA" /locus_tag="BSU_34130" /old_locus_tag="BSU34130" CDS complement(3370700..3371551) /gene="ganQ" /locus_tag="BSU_34140" /old_locus_tag="BSU34140" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:15849754, 16850406, 17056685, 27501980" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15849754, 16850406, 17056685, 27501980; Product type t: transporter" /codon_start=1 /transl_table=11 /product="galacto-oligosaccharides (galactan) oligomer permease" /protein_id="NP_391294.1" /db_xref="EnsemblGenomes-Gn:BSU34140" /db_xref="EnsemblGenomes-Tr:CAB15419" /db_xref="GOA:O07011" /db_xref="InterPro:IPR000515" /db_xref="InterPro:IPR035906" /db_xref="SubtiList:BG12438" /db_xref="UniProtKB/Swiss-Prot:O07011" /translation="MLADMKVRRYIRLLFSYLLLAFMAVIIVYPLLWTAGASFNPGNS LISTSIIPKHPTFDHYKELFAGKESLQYVQWYVNSMKISLFTMAGSLLCVTFTAYAFS RFRFKGRKYALTLFLLLQMIPQFSALIALFVLAQILGMINSHWLLILLYIGGLIPMNT YLMKGYMDSIPMDLDESAKIDGASSTRIFFQIILPLSKPMAAVVAMNGFTGPLGDFVL SSTILRTPESYTLPVGLFNLVNDVMGASYTTFAAGALLISIPVAVIFIMLQKNFVSGL TAGGTKG*" gene complement(3370700..3371551) /gene="ganQ" /locus_tag="BSU_34140" /old_locus_tag="BSU34140" CDS complement(3371555..3372811) /gene="ganP" /locus_tag="BSU_34150" /old_locus_tag="BSU34150" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:11160890, 15849754, 16850406, 17056685, 27501980" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11160890, 15849754, 16850406, 17056685, 27501980; Product type t : transporter" /codon_start=1 /transl_table=11 /product="galacto-oligosaccharides (galactan) oligomer permease" /protein_id="NP_391295.1" /db_xref="EnsemblGenomes-Gn:BSU34150" /db_xref="EnsemblGenomes-Tr:CAB15420" /db_xref="GOA:O32261" /db_xref="InterPro:IPR000515" /db_xref="InterPro:IPR035277" /db_xref="InterPro:IPR035906" /db_xref="SubtiList:BG12437" /db_xref="UniProtKB/Swiss-Prot:O32261" /translation="MQHRQVALLLSIIPGLGQFYNKQWIKGIVFLFLGASFFAVFGDL LNMGFWGIFTLGTEVPRDNSVFLLAEGIIAVIVTCFGLAVYYVNLRDAFQSGKQRDEN KPLSSLKEQYQHIISEGYPYVVSGPSLFILIFAVIFPILFSFALAFTNYDLYHSPPAK LIDWVGFQTFANIFTVDIWRSTFFDVLAWTVVWTLAASTLQVTLGIFLAIIVNQKDLR FKRFFRTILILPWAVPGFVTILIFAGLFNDSFGAMNHDILAFFGIDPLPWMTDANWSR LALILMQGWLGFPYIFLVSTGVLQSIPDDLYEAATIDGASVFSKLRYITLPMVFIAMA PIIITQFTFNFNNFNIIYLFNGGGPAVTGSTAGGTDILVSWIYKLTMQSSQYSLAAAL TILLSVFVISIALWQFRQTKSFKEEA*" gene complement(3371555..3372811) /gene="ganP" /locus_tag="BSU_34150" /old_locus_tag="BSU34150" CDS complement(3372851..3374116) /gene="ganS" /locus_tag="BSU_34160" /old_locus_tag="BSU34160" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:11682178, 27501980" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11682178, 27501980; Product type t: transporter" /codon_start=1 /transl_table=11 /product="polygalactose / cyclodextrin-binding lipoprotein" /protein_id="NP_391296.1" /db_xref="EnsemblGenomes-Gn:BSU34160" /db_xref="EnsemblGenomes-Tr:CAB15421" /db_xref="GOA:O07009" /db_xref="InterPro:IPR006060" /db_xref="SubtiList:BG12436" /db_xref="UniProtKB/Swiss-Prot:O07009" /translation="MKMAKKCSVFMLCAAVSLSLAACGPKESSSAKSSSKGSELVVWE DKEKSNGIKDAVAAFEKEHDVKVKVVEKPYAKQIEDLRMDGPAGTGPDVLTMPGDQIG TAVTEGLLKELHVKKDVQSLYTDASIQSQMVDQKLYGLPKAVETTVLFYNKDLITEKE LPKTLEEWYDYSKKTADGSKFGFLALFDQIYYAESVMSGYGGYIFGKAKDGSYNPSDI GINNEGAVKGAALIQKFYKDGLFPAGIIGEQGINVLESLFTEGKAAAIISGPWNVEAF SNAGINYGITKLPKLENGKNMSSFIGVKSYNVSAFSKNEELAQELAVFLANEKNSKTR YEETKEVPAVKSLANDPAIMKSEAARAVTEQSRFSEPTPNIPEMNEIWTPADSALQTV ATGKADPKQALDQAAETAKGQIKAKHSGK*" gene complement(3372851..3374116) /gene="ganS" /locus_tag="BSU_34160" /old_locus_tag="BSU34160" promotor_-10 complement(3374148..3374167) /Source="Nicolas_upshift_promotors" /id="U2693" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.968031968031968" /psig=1 /xcortree=325 /SigmaFactorBS="tttatttaggtaaaaaaatttactctatgaagtaaatagttT GTTTACAcattttctcaggcaTGCTATATTATCTTTAAAGCgctttcattcctaccga a" /listShort="cycB, ganP, ganQ, ganA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3374170) /Source="Nicolas_upshifts" /id="U2693" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.968031968031968" /psig=1 /xcortree=325 /SigmaFactorBS="tttatttaggtaaaaaaatttactctatgaagtaaatagttT GTTTACAcattttctcaggcaTGCTATATTATCTTTAAAGCgctttcattcctaccga a" /listShort="cycB, ganP, ganQ, ganA" /GFF_Attribute="listLong" promotor_-35 complement(3374182..3374189) /Source="Nicolas_upshift_promotors" /id="U2693" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.968031968031968" /psig=1 /xcortree=325 /SigmaFactorBS="tttatttaggtaaaaaaatttactctatgaagtaaatagttT GTTTACAcattttctcaggcaTGCTATATTATCTTTAAAGCgctttcattcctaccga a" /listShort="cycB, ganP, ganQ, ganA" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3374257..3375249) /gene="ganR" /locus_tag="BSU_34170" /old_locus_tag="BSU34170" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:2104611, 9287030, 10486575, 17056685, 27501980, 28617843" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 2104611, 9287030, 10486575, 17056685, 27501980, 28617843; Product type r : regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator of the galactan degradation operon (GanR / beta-1,4-galactobiose)" /protein_id="NP_391297.1" /db_xref="EnsemblGenomes-Gn:BSU34170" /db_xref="EnsemblGenomes-Tr:CAB15422" /db_xref="GOA:O07008" /db_xref="InterPro:IPR000843" /db_xref="InterPro:IPR010982" /db_xref="InterPro:IPR028082" /db_xref="SubtiList:BG12435" /db_xref="UniProtKB/Swiss-Prot:O07008" /translation="MATIKDIAQEAGFSISTVSRVLNNDESLSVPDETREKIYEAAEK LNYRKKTVRPLVKHIAFLYWLTDKEELEDVYFKTMRLEVEKLAKAFNVDMTTYKIADG IESIPEHTEGFIAVGTFSDEELAFLRNLTENGVFIDSTPDPDHFDSVRPDLAQMTRKT VNILTEKGHKSIGFIGGTYKNPNTNQDEMDIREQTFRSYMREKAMLDERYIFCHRGFS VENGYRLMSAAIDTLGDQLPTAFMIAADPIAVGCLQALNEKGIAIPNRVSIVSINNIS FAKYVSPPLTTFHIDIHELCKNAVQLLLEQVQDKRRTVKTLYVGAELIVRKSMN*" gene complement(3374257..3375249) /gene="ganR" /locus_tag="BSU_34170" /old_locus_tag="BSU34170" downshifts complement(3374291) /Source="Nicolas_upshifts" /id="D1775" /incds=0 /nref=2 /ntot=55 /MaxReadThrough="1.40325" /MaxDrop="2.80992" /score="14.7399792" /energy="-8.3" /TU="NA" /idTUdmin="U2694" /TUdmin=1111 /isTUend="FALSE" S_feature complement(3375379..3375428) /Source="Nicolas_S_feature" /locus_tag="new_3509781_3509830_c" /HighExp="Sw, BC, M0t90, M40t90, B60, Lbstat, Lbtran, S2, B36, nit" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.29208099999999998" /TUshortSig="NA" /TUshortPSig="NA" /TUlongSig="NA" /TUlongPSig="NA" /label="S1307" downshifts complement(3375402) /Source="Nicolas_upshifts" /id="D1776" /incds=0 /nref=88 /ntot=240 /MaxReadThrough="1.88481" /MaxDrop="5.0699" /score="7.28170345" /energy="-13.7" /TU="NA" /idTUdmin="U2694" /TUdmin=0 /isTUend="TRUE" CDS complement(3375429..3376088) /gene="lutR" /locus_tag="BSU_34180" /old_locus_tag="BSU34180" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:18604637, 24196425, 25031425" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 18604637, 24196425, 25031425; Product type r: regulator" /codon_start=1 /transl_table=11 /product="L-lactate utilization global transcriptional regulator (GntR family)" /protein_id="NP_391298.2" /db_xref="EnsemblGenomes-Gn:BSU34180" /db_xref="EnsemblGenomes-Tr:CAB15423" /db_xref="GOA:O07007" /db_xref="InterPro:IPR000524" /db_xref="InterPro:IPR008920" /db_xref="InterPro:IPR011711" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG12434" /db_xref="UniProtKB/Swiss-Prot:O07007" /translation="MIKNGELKPGDKLDSVQALAESFQVSRSAVREALSALKAMGLVE MKQGEGTYLKEFELNQISQPLSAALLMKKEDVKQLLEVRKLLEIGVASLAAEKRTEAD LERIQDALKEMGSIEADGELGEKADFAFHLALADASQNELLKHLMNHVSSLLLETMRE TRKIWLFSKKTSVQRLYEEHERIYNAVAAGNGAQAEAAMLAHLTNVEDVLSGYFEENV Q*" gene complement(3375429..3376088) /gene="lutR" /locus_tag="BSU_34180" /old_locus_tag="BSU34180" S_feature complement(3376089..3376194) /Source="Nicolas_S_feature" /locus_tag="new_3510491_3510596_c" /HighExp="M0t90, Lbstat, BC, M40t90, Lbtran, Sw, S2, B60, ferm, T3.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.69672000000000001" /TUshortSig="SigA" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S1308" promotor_-10 complement(3376186..3376205) /Source="Nicolas_upshift_promotors" /id="U2694" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.967032967032967" /psig="0.999000999001" /xcortree=1596 /SigmaFactorBS="agtacaagactttttgacaaaatagtcaaaatCTTTtggcgg cccacaaaACAGAGTATAATAGATCGTAaacagccagacctacaagttacggggtgaa t" /listShort="S1308, yvfI" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3376195) /Source="Nicolas_upshifts" /id="U2694" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.967032967032967" /psig="0.999000999001" /xcortree=1596 /SigmaFactorBS="agtacaagactttttgacaaaatagtcaaaatCTTTtggcgg cccacaaaACAGAGTATAATAGATCGTAaacagccagacctacaagttacggggtgaa t" /listShort="S1308, yvfI" /GFF_Attribute="listLong" promotor_-35 complement(3376220..3376223) /Source="Nicolas_upshift_promotors" /id="U2694" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.967032967032967" /psig="0.999000999001" /xcortree=1596 /SigmaFactorBS="agtacaagactttttgacaaaatagtcaaaatCTTTtggcgg cccacaaaACAGAGTATAATAGATCGTAaacagccagacctacaagttacggggtgaa t" /listShort="S1308, yvfI" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 3376247..3376254 /Source="Nicolas_upshift_promotors" /id="U2695" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.516483516483517" /psig=1 /xcortree=494 /SigmaFactorBS="gtgggccgccaaaagattttgactattttgtcaaaaagTCTT GTACtttgatttttttcaAAATATAATGCTAGGTAACTggtcttattacccagtcatc a" /listShort="S1309, yvfH" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3376269..3376288 /Source="Nicolas_upshift_promotors" /id="U2695" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.516483516483517" /psig=1 /xcortree=494 /SigmaFactorBS="gtgggccgccaaaagattttgactattttgtcaaaaagTCTT GTACtttgatttttttcaAAATATAATGCTAGGTAACTggtcttattacccagtcatc a" /listShort="S1309, yvfH" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3376269 /Source="Nicolas_upshifts" /id="U2695" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.516483516483517" /psig=1 /xcortree=494 /SigmaFactorBS="gtgggccgccaaaagattttgactattttgtcaaaaagTCTT GTACtttgatttttttcaAAATATAATGCTAGGTAACTggtcttattacccagtcatc a" /listShort="S1309, yvfH" /GFF_Attribute="listLong" S_feature 3376272..3376377 /Source="Nicolas_S_feature" /locus_tag="new_3510674_3510779" /HighExp="T1.30H, S1, T1.0H, M40t90, T2.0H, M0t90, T3.0H, T2.30H, T0.30H, G/S" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1309" promotor_-10 complement(3376278..3376295) /Source="Nicolas_upshift_promotors" /id="U2696" /multdbtbs="-" /comp="M6" /sig="Sig-" /pcomp="0.543456543456543" /psig="0.330669330669331" /xcortree=381 /SigmaFactorBS="atgtaagcggtttctatagatgatatgatcatcTGATGACtg ggtaaTAAGACCAGTTACCTAGCattatattttgaaaaaaatcaaagtacaagacttt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3376282) /Source="Nicolas_upshifts" /id="U2696" /multdbtbs="-" /comp="M6" /sig="Sig-" /pcomp="0.543456543456543" /psig="0.330669330669331" /xcortree=381 /SigmaFactorBS="atgtaagcggtttctatagatgatatgatcatcTGATGACtg ggtaaTAAGACCAGTTACCTAGCattatattttgaaaaaaatcaaagtacaagacttt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(3376303..3376309) /Source="Nicolas_upshift_promotors" /id="U2696" /multdbtbs="-" /comp="M6" /sig="Sig-" /pcomp="0.543456543456543" /psig="0.330669330669331" /xcortree=381 /SigmaFactorBS="atgtaagcggtttctatagatgatatgatcatcTGATGACtg ggtaaTAAGACCAGTTACCTAGCattatattttgaaaaaaatcaaagtacaagacttt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" CDS 3376378..3378069 /gene="lutP" /locus_tag="BSU_34190" /old_locus_tag="BSU34190" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1b: Function from experimental evidences in the studied species; PubMedId: 25031425; Product type t: transporter" /codon_start=1 /transl_table=11 /product="L-lactate permease" /protein_id="NP_391299.1" /db_xref="EnsemblGenomes-Gn:BSU34190" /db_xref="EnsemblGenomes-Tr:CAB15424" /db_xref="GOA:P71067" /db_xref="InterPro:IPR003804" /db_xref="SubtiList:BG11875" /db_xref="UniProtKB/Swiss-Prot:P71067" /translation="MQWTQAYTPIGGNLLLSALAALVPIIFFFWALAIKRMKGYTAGL ATLGIALIIAVLVYRMPAEKALMSATQGAVYGLLPIGWIIVTSVFLYKITVKTGQFDI IRSSVLSITDDRRLQALLIAFSFGAFLEGAAGFGAPVAISAALLVGLGFNPLYAAGIC LIANTAPVAFGAIGIPITAVEGPTGIPAMEISQMVGRQLPFLSVFIPLYLIIIMSGFR KALEIWPAILVSGVSFAVVQYLSSNFLGPELPDVLSALVSMAALAVFLKWWKPKTTFR FAGEQESAASIETARTNPAAPAYRGGQIFKAWSPFLLLTAMISVWGIPSVKSALTGHY EGSAVFLKWLNAVGEKLTFSPGVPFLNNQIVNADGTPIEAVYKLEVLGSAGTAILIAA VLSKFITAISWKDWGTVFKETVQELKLPILTIASVVGFAYVTNSSGMSTTLGMTLALT GSMFTFFSPVLGWLGVFITGSDTSANLLFGNLQKVTALSVGMDPVLSVAANSSGGVTG KMISPQSIAVACAAVGLAGKESDLFRFTIKHSLFLLLLVCIITFLQHHVFSWMIP*" gene 3376378..3378069 /gene="lutP" /locus_tag="BSU_34190" /old_locus_tag="BSU34190" downshifts 3378054 /Source="Nicolas_upshifts" /id="D1777" /incds=0 /nref=153 /ntot=245 /MaxReadThrough="4.82757" /MaxDrop="5.44233" /score="20.8815301" /energy="-11.7" /TU="NA" /idTUdmin="U2695" /TUdmin=0 /isTUend="TRUE" CDS complement(3378096..3379406) /gene="sigL" /locus_tag="BSU_34200" /old_locus_tag="BSU34200" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:11274109, 12533460, 12634342, 16166551, 16585774" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11274109, 12533460, 12634342, 16166551, 16585774; Product type r: regulator" /codon_start=1 /transl_table=11 /product="RNA polymerase sigma-54 factor (sigma-L)" /protein_id="NP_391300.1" /db_xref="EnsemblGenomes-Gn:BSU34200" /db_xref="EnsemblGenomes-Tr:CAB15425" /db_xref="GOA:P24219" /db_xref="InterPro:IPR000394" /db_xref="InterPro:IPR007046" /db_xref="InterPro:IPR007634" /db_xref="InterPro:IPR036388" /db_xref="SubtiList:BG10748" /db_xref="UniProtKB/Swiss-Prot:P24219" /translation="MDMKLQQVQVLKPQLTQELRQAITLLGYHSAELAEYIDELSLEN PLIERKETDTPPLSYHKTNKNRMNAQEAGLQLSNPQKTLQDALKQQSLDMNLTNTEKK IFNYLIHSLDSNGYLEEDIEEAARRLSVSAKEAEAVLAKLQSLEPAGIGARSLQECIL LQLQRLPNRNEQAEMLVSAHFDAFAQKKWKTLSVETGIPLHTIQDISDDIAALHPRPG LLFARPEQDVYIEPDIFITVKNGHIAAELNTRSFPEIDLHPQYRTLLSSGSCQDTVSY LSAKYQEWRWLSRALRQRKQTITRIINELITRQKDFFLKGRSAMKPLTLREVADCLSL HESTVSRAIKGKTIQTPYGLFEMKLFFSAKAEASGDGDASNYAVKTHLENLINQEDKT KPLSDQKLVDLLYEQHGIQISRRTVAKYRDQMNIPSSAARKRYK*" gene complement(3378096..3379406) /gene="sigL" /locus_tag="BSU_34200" /old_locus_tag="BSU34200" S_feature 3378099..3379169 /Source="Nicolas_S_feature" /locus_tag="new_3512501_3513571" /HighExp="M9-stat, T1.30H, S1, Sw, T1.0H, T2.0H, T0.30H, G/S, T3.30H, T2.30H" /AntisenseName="sigL" /AntisenseCor="0.63927172079726402" /AntisenseRegPval="-31.6" /CDS_PredictionProba="NA" /TUshortSig="NA" /TUshortPSig="NA" /TUlongSig="NA" /TUlongPSig="NA" /label="S1310" downshifts complement(3378108) /Source="Nicolas_upshifts" /id="D1778" /incds=0 /nref=62 /ntot=219 /MaxReadThrough="2.33779" /MaxDrop="5.56948" /score="28.2409666" /energy="-11.7" /TU="NA" /idTUdmin="U2698" /TUdmin=0 /isTUend="TRUE" misc_feature 3379226..3379245 /Source="Nicolas_upshift_promotors" /id="U2697" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.656343656343656" /psig=1 /xcortree=2629 /SigmaFactorBS="tttgcggattacttaattgaaggcccgcttcctgtgcattca tcctgtttttgtttgtttTATGGTAAGATAGTGGCGGTgtgtctgtttcctttcgttc a" /listShort="S1311, yvfG" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" S_feature 3379226..3379484 /Source="Nicolas_S_feature" /locus_tag="new_3513628_3513886" /HighExp="LBGstat, LBGexp, G180, Paraq, H2O2, LBGtran, Oxctl, Lbexp, dia0, HPh" /AntisenseName="sigL" /AntisenseCor="-0.50245218771496702" /AntisenseRegPval="-17.899999999999999" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1311" upshifts 3379226 /Source="Nicolas_upshifts" /id="U2697" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.656343656343656" /psig=1 /xcortree=2629 /SigmaFactorBS="tttgcggattacttaattgaaggcccgcttcctgtgcattca tcctgtttttgtttgtttTATGGTAAGATAGTGGCGGTgtgtctgtttcctttcgttc a" /listShort="S1311, yvfG" /GFF_Attribute="listLong" promotor_-10 complement(3379420..3379439) /Source="Nicolas_upshift_promotors" /id="U2698" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.94005994005994" /psig=1 /xcortree=424 /SigmaFactorBS="agttcagacatttctttggcagctcctttttcataaatGTAT acggtgtgatctcaATCATGTACAATGAAGAAAGgggagtgagcaagatggatatgaa a" /listShort="sigL" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3379435) /Source="Nicolas_upshifts" /id="U2698" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.94005994005994" /psig=1 /xcortree=424 /SigmaFactorBS="agttcagacatttctttggcagctcctttttcataaatGTAT acggtgtgatctcaATCATGTACAATGAAGAAAGgggagtgagcaagatggatatgaa a" /listShort="sigL" /GFF_Attribute="listLong" promotor_-35 complement(3379454..3379457) /Source="Nicolas_upshift_promotors" /id="U2698" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.94005994005994" /psig=1 /xcortree=424 /SigmaFactorBS="agttcagacatttctttggcagctcctttttcataaatGTAT acggtgtgatctcaATCATGTACAATGAAGAAAGgggagtgagcaagatggatatgaa a" /listShort="sigL" /GFF_Attribute="listLong" /label="promotor_-35" CDS 3379485..3379703 /gene="yvfG" /locus_tag="BSU_34210" /old_locus_tag="BSU34210" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_391301.1" /db_xref="EnsemblGenomes-Gn:BSU34210" /db_xref="EnsemblGenomes-Tr:CAB15426" /db_xref="InterPro:IPR018590" /db_xref="PDB:2GSV" /db_xref="PDB:2JS1" /db_xref="SubtiList:BG11876" /db_xref="UniProtKB/Swiss-Prot:P71066" /translation="MSELFSVPYFIENLKQHIEMNQSEDKIHAMNSYYRSVVSTLVQD QLTKNAVVLKRIQHLDEAYNKVKRGESK*" gene 3379485..3379703 /gene="yvfG" /locus_tag="BSU_34210" /old_locus_tag="BSU34210" downshifts 3379682 /Source="Nicolas_upshifts" /id="D1779" /incds=0 /nref=53 /ntot=250 /MaxReadThrough="3.27525" /MaxDrop="4.21929" /score="-0.306638574" /energy="-13.4" /TU="U2697" /idTUdmin="U2697" /TUdmin="-418" /isTUend="FALSE" CDS complement(3379713..3380681) /gene="epsO" /locus_tag="BSU_34220" /old_locus_tag="BSU34220" /EC_number="2.-.-.-" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1c: Function from experimental evidences in the studied genus; PubMedId: 1097084, 115661000, 20720312, 23378512; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="pyruvyl transferase for matrix biofilm formation" /protein_id="NP_391302.1" /db_xref="EnsemblGenomes-Gn:BSU34220" /db_xref="EnsemblGenomes-Tr:CAB15427" /db_xref="GOA:P71065" /db_xref="InterPro:IPR007345" /db_xref="SubtiList:BG11874" /db_xref="UniProtKB/Swiss-Prot:P71065" /translation="MDSKHSMISLKQKLSGLLDVIPKQSEIIYADYPLYGNVGDLFIM KGTEAFFKEHGIRVRKRWNPDNFPIGRKLDPNLIIVCQGGGNFGDLYPYYQGFREKIV QTYPNHKIVILPQSIYFQNKDNLKRTAEIFSKHANLHIMTREKASYATAQAYFTTNHI QLLPDMAHQLFPVIPTQQPSNQKLRFIRTDHEANQALQEHAEAESYDWRTVLSASDRR TIAFLQTLNVLNKKAGNPLPIAYIWEKYSDYIVQKAIRFFSRYESVETSRLHGHILSS LLQKENTVIDNSYGKNANYFHTWMEGVPSTRLIQHASKKENLPAHM*" gene complement(3379713..3380681) /gene="epsO" /locus_tag="BSU_34220" /old_locus_tag="BSU34220" CDS complement(3380660..3381826) /gene="epsN" /locus_tag="BSU_34230" /old_locus_tag="BSU34230" /EC_number="2.6.1.-" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15661000, 20720312, 23378512, 27084765, 27897378; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative aminotransferase involved in biofilm matrix formation" /protein_id="NP_391303.2" /db_xref="EnsemblGenomes-Gn:BSU34230" /db_xref="EnsemblGenomes-Tr:CAB15428" /db_xref="GOA:Q795J3" /db_xref="InterPro:IPR000653" /db_xref="InterPro:IPR015421" /db_xref="InterPro:IPR015422" /db_xref="InterPro:IPR015424" /db_xref="SubtiList:BG11873" /db_xref="UniProtKB/Swiss-Prot:Q795J3" /translation="MHKKIYLSPPHMSGREQHYISEAFRSNWIAPLGPLVNSFEEQLA ERVGVKAAAAVGSGTAAIHLALRLLEVKEGDSVFCQSFTFVATANPILYEKAVPVFID SEPDTWNMSPTALERALEEAKRNGTLPKAVIAVNLYGQSAKMDEIVSLCDAYGVPVIE DAAESLGTVYKGKQSGTFGRFGIFSFNGNKIITTSGGGMLVSNDEAAIEKARFLASQA REPAVHYQHSEIGHNYRLSNILAGVGIAQLEVLDERVEKRRTIFTRYKNALGHLDGVR FMPEYAAGVSNRWLTTLTLDNGLSPYDIVQRLAEENIEARPLWKPLHTQPLFDPALFY SHEDTGSVCEDLFKRGICLPSGSNMTEDEQGRVIEVLLHLFHTVEVKKWTASIR*" gene complement(3380660..3381826) /gene="epsN" /locus_tag="BSU_34230" /old_locus_tag="BSU34230" CDS complement(3381831..3382481) /gene="epsM" /locus_tag="BSU_34240" /old_locus_tag="BSU34240" /function="16.5: Explore" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15661000, 27897378; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative O-acetyltransferase involved in biofilmmatrix formation" /protein_id="NP_391304.1" /db_xref="EnsemblGenomes-Gn:BSU34240" /db_xref="EnsemblGenomes-Tr:CAB15429" /db_xref="GOA:P71063" /db_xref="InterPro:IPR001451" /db_xref="InterPro:IPR011004" /db_xref="InterPro:IPR018357" /db_xref="InterPro:IPR020019" /db_xref="SubtiList:BG11872" /db_xref="UniProtKB/Swiss-Prot:P71063" /translation="MKNVAIVGDGGHGKVIRELINARSDTRLAAVLDDKFKTFEGGKE WYTGPPKAVTELRRLIPDVLFLIAVGNNSVRKQLAERLGLGKDDFITLIHPSAIVSKS AVIGEGTVIMAGAIIQADARIGAHCIINTGAVAEHDNQISDYVHLSPRATLSGAVSVQ EGAHVGTGASVIPQIIIGAWSIVGAGSAVIRSIPDRVTAAGAPARIISSIQTSNKG*" gene complement(3381831..3382481) /gene="epsM" /locus_tag="BSU_34240" /old_locus_tag="BSU34240" CDS complement(3382478..3383086) /gene="epsL" /locus_tag="BSU_34250" /old_locus_tag="BSU34250" /EC_number="2.7.-.-" /function="16.5: Explore" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15175311, 15661000, 23378512; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative phosphotransferase involved in extracellular matrix synthesis" /protein_id="NP_391305.1" /db_xref="EnsemblGenomes-Gn:BSU34250" /db_xref="EnsemblGenomes-Tr:CAB15430" /db_xref="GOA:P71062" /db_xref="InterPro:IPR003362" /db_xref="SubtiList:BG11871" /db_xref="UniProtKB/Swiss-Prot:P71062" /translation="MILKRLFDLTAAIFLLCCTSVIILFTIAVVRLKIGSPVFFKQVR PGLHGKPFTLYKFRTMTDERDSKGNLLPDEVRLTKTGRLIRKLSIDELPQLLNVLKGD LSLVGPRPLLMDYLPLYTEKQARRHEVKPGITGWAQINGRNAISWEKKFELDVWYVDN WSFFLDLKILCLTVRKVLVSEGIQQTNHVTAERFTGSGDVSS*" gene complement(3382478..3383086) /gene="epsL" /locus_tag="BSU_34250" /old_locus_tag="BSU34250" CDS complement(3383083..3384600) /gene="epsK" /locus_tag="BSU_34265" /old_locus_tag="BSU34265" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15175311, 15661000, 15849754, 16850406, 26078454, 27897378; Product type t : transporter" /codon_start=1 /transl_table=11 /product="putative extracellular matrix component exporter; putative cyclic di-GMP receptor" /protein_id="YP_003097789.1" /db_xref="EnsemblGenomes-Gn:BSU34265" /db_xref="EnsemblGenomes-Tr:CAX52695" /db_xref="GOA:P71060" /db_xref="InterPro:IPR002797" /db_xref="InterPro:IPR029303" /db_xref="UniProtKB/Swiss-Prot:P71060" /translation="MKFTINFSANLTAFLLSVFLSVWMTPFIVKTLGVEAFGFVHLTQ NVINYFSVITVALSSVVVRFFSVAAHRGEREKANAYISNYLAASVLISLLLLLPLAGS AFFIDRVMNVPQALLADVRLSILIGSVLFILTFLMAGFGAAPFYANRLYITSSIQAVQ MLIRVLSVLLLFACFAPKIWQIQLAALAGAVIASVLSFYFFKKLIPWFSFRMKDLSFR TSKELFQAGAWSSVNQIGVLLFLQIDLLTANLMLGASASGKYAAIIQFPLLLRSLAGT VASLFAPIMTSYYSKGDMEGLMNYANKAVRLNGLLLALPAALLGGLAGPFLTIWLGPS FSTIAPLLFIHAGYLVVSLAFMPLFYIWTAFNQQKTPAIVTLLLGAVNVVLAVTLSGP AHLGLYGITLAGAISLILKNAIFTPLYVSRITGYKKHVFLKGIIGPLSAAVFAWTVCK AIQFIVKIDSWPSLIATGVTVSFCYAVFAFMLVCTKEERQLVLKRFRKTKGAVNL*" gene complement(3383083..3384600) /gene="epsK" /locus_tag="BSU_34265" /old_locus_tag="BSU34265" CDS complement(3384597..3385631) /gene="epsJ" /locus_tag="BSU_34280" /old_locus_tag="BSU34280" /EC_number="2.4.-.-" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15661000, 20720312, 26078454, 27897378; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative glycosyl transferase involved in biofilm matrix formation" /protein_id="NP_391308.1" /db_xref="EnsemblGenomes-Gn:BSU34280" /db_xref="EnsemblGenomes-Tr:CAB15433" /db_xref="GOA:P71059" /db_xref="InterPro:IPR001173" /db_xref="InterPro:IPR029044" /db_xref="SubtiList:BG11868" /db_xref="UniProtKB/Swiss-Prot:P71059" /translation="MIPLVSIIVPMYNVEPFIEECIDSLLRQTLSDIEIILVNDGTPD RSGEIAEDYAKRDARIRVIHQANGGLSSARNTGIKAARGTYIGFVDGDDYVSSAMFQR LTEEAEQNQLDIVGCGFYKQSSDRRTYVPPQLEANRVLTKPEMTEQLKHAHETRFIWY VWRYLYRRELFERANLLFDEDIRFAEDSPFNLSAFREAERVKMLDEGLYIYRENPNSL TEIPYKPAMDEHLQKQYQAKIAFYNHYGLAGACKEDLNVYICRHQLPMLLANACASPN SPKDIKKKIRQILSYDMVRQAVRHTPFQHEKLLRGERLVLALCKWRLTFLIKLFFEQR GTMKGSAKQA*" gene complement(3384597..3385631) /gene="epsJ" /locus_tag="BSU_34280" /old_locus_tag="BSU34280" CDS complement(3385628..3386704) /gene="epsI" /locus_tag="BSU_34290" /old_locus_tag="BSU34290" /EC_number="2.-.-.-" /function="16.8: Protect" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15173185, 15661000, 20720312, 26078454; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative polysaccharide pyruvyl transferase involved in biofilm matrix formation" /protein_id="NP_391309.1" /db_xref="EnsemblGenomes-Gn:BSU34290" /db_xref="EnsemblGenomes-Tr:CAB15434" /db_xref="GOA:P71058" /db_xref="InterPro:IPR007345" /db_xref="SubtiList:BG11867" /db_xref="UniProtKB/Swiss-Prot:P71058" /translation="MSLQSLKINFAEWLLLKVKYPSQYWLGAADQPVKAAAHQKKIIL TLLPSHDNLGDHAIAYASKAFLEQEYPDFDIVEVDMKDIYKSAKSLIRSRHPEDMVFI IGGGNMGDLYRYEEWTRRFIIKTFHDYRVVQLPATAHFSDTKKGRKELKRAQKIYNAH PGLLLMARDETTYQFMKQHFQEKTILKQPDMVLYLDRSKAPAEREGVYMCLREDQESV LQEEQRNRVKAALCEEFGEIKSFTTTIGRRVSRDTREHELEALWSKLQSAEAVVTDRL HGMIFCALTGTPCVVIRSFDHKVMEGYQWLKDIPFMKLIEHPEPERVTAAVNELLTKE TSRAGFPRDVYFKGLRDKISGEAQ*" gene complement(3385628..3386704) /gene="epsI" /locus_tag="BSU_34290" /old_locus_tag="BSU34290" CDS complement(3386709..3387743) /gene="epsH" /locus_tag="BSU_34300" /old_locus_tag="BSU34300" /EC_number="2.-.-.-" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15083514, 15661000; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative glycosyltransferase involved in biofilmformation" /protein_id="NP_391310.1" /db_xref="EnsemblGenomes-Gn:BSU34300" /db_xref="EnsemblGenomes-Tr:CAB15435" /db_xref="GOA:P71057" /db_xref="InterPro:IPR001173" /db_xref="InterPro:IPR029044" /db_xref="SubtiList:BG11866" /db_xref="UniProtKB/Swiss-Prot:P71057" /translation="METPAVSLLVAVYNTETYIRTCLESLRNQTMDNIEIIIVNDGSA DASPDIAEEYAKMDNRFKVIHQENQGLGAVRNKGIEAARGEFIAFIDSDDWIEPDYCE QMLRTAGDETDLVICNYAAEFEDTGKTMDSDIAQTYQDQPKEHYIKALFEGKVRGFSW NKLYRRSMIEAHRLSFPLRGELEHVEDQFFSFRAHFFARSVSYVKTPLYHYRIHLSSI VQRYQKKLFESGLALYETNAAFLQENNKLEEYRKELDTFIVLHSSICMLNEWKTSGSR RLFEKLRNVGVICADPVFQESLSKTGTAPFDAKRSCLLLMAKYRMIPFVAMASAVYQR VIEYKMRNRG*" gene complement(3386709..3387743) /gene="epsH" /locus_tag="BSU_34300" /old_locus_tag="BSU34300" CDS complement(3387768..3388871) /gene="epsG" /locus_tag="BSU_34310" /old_locus_tag="BSU34310" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:15175311, 15661000, 15849754, 16850406, 22451411" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15175311, 15661000, 15849754, 16850406, 22451411; Product type f: factor" /codon_start=1 /transl_table=11 /product="biofilm extracellular matrix formation chain-length determining factor" /protein_id="NP_391311.1" /db_xref="EnsemblGenomes-Gn:BSU34310" /db_xref="EnsemblGenomes-Tr:CAB15436" /db_xref="GOA:P71056" /db_xref="SubtiList:BG11865" /db_xref="UniProtKB/Swiss-Prot:P71056" /translation="MIVYAVNMGIVFIWSWFAKMCGGRDDSLATGYRPNKLLIWIPLA SLVLVSGLRYRVGTDFQTYTLLYELAGDYQNVWQIFGFGTAKTATDPGFTALLWLMNF ITEDPQIMYFTVAVVTYSFIMKTLADYGRPFELSVFLFLGTFHYYASFNGIRQYMVAA VLFWAIRYIISGNWKRYFLIVLVSSLFHSSALIMIPVYFIVRRKAWSPAIFGLSALFL GMTFLYQKFISVFVVVLENSSYSHYEKWLMTNTNGMNVIKIAVLVLPLFLAFCYKERL RSLWPQIDIVVNLCLLGFLFGLLATKDVIFARFNIYFGLYQMILVPYFVRIFDEKSNA LIYIAIVVCYFLYSYLLMPVDSSVLPYRTIFSR*" gene complement(3387768..3388871) /gene="epsG" /locus_tag="BSU_34310" /old_locus_tag="BSU34310" CDS complement(3388868..3390022) /gene="epsF" /locus_tag="BSU_34320" /old_locus_tag="BSU34320" /EC_number="2.-.-.-" /function="16.5: Explore" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15175311, 15661000, 22451411; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative glycosyltransferase involved in matrix formation (chain-length determination)" /protein_id="NP_391312.1" /db_xref="EnsemblGenomes-Gn:BSU34320" /db_xref="EnsemblGenomes-Tr:CAB15437" /db_xref="GOA:P71055" /db_xref="InterPro:IPR001296" /db_xref="InterPro:IPR028098" /db_xref="SubtiList:BG11864" /db_xref="UniProtKB/Swiss-Prot:P71055" /translation="MNSSQKRVLHVLSGMNRGGAETMVMNLYRKMDKSKVQFDFLTYR NDPCAYDEEILSLGGRLFYVPSIGQSNPLTFVRNVRNAIKENGPFSAVHAHTDFQTGF IALAARLAGVPVRVCHSHNTSWKTGFNWKDRLQLLVFRRLILANATALCACGEDAGRF LFGQSNMERERVHLLPNGIDLELFAPNGQAADEEKAARGIAADRLIIGHVARFHEVKN HAFLLKLAAHLKERGIRFQLVLAGDGPLCGEIEEEARQQNLLSDVLFLGTEERIHELM RTFDVFVMPSLYEGLPVVLVEAQASGLPCIISDSITEKVDAGLGLVTRLSLSEPISVW AETIARAAAAGRPKREFIKETLAQLGYDAQQNVGALLNVYNISTEKDHNR*" gene complement(3388868..3390022) /gene="epsF" /locus_tag="BSU_34320" /old_locus_tag="BSU34320" CDS complement(3390015..3390851) /gene="epsE" /locus_tag="BSU_34330" /old_locus_tag="BSU34330" /EC_number="2.-.-.-" /function="16.8: Protect" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:15175311, 15661000, 21170308, 22720735, 23480406" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15175311, 15661000, 21170308, 22720735, 23480406; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="bifunctional flagellar clutch and glycosyltransferase acting during biofilm formation" /protein_id="NP_391313.2" /db_xref="EnsemblGenomes-Gn:BSU34330" /db_xref="EnsemblGenomes-Tr:CAB15438" /db_xref="GOA:P71054" /db_xref="InterPro:IPR001173" /db_xref="InterPro:IPR029044" /db_xref="SubtiList:BG11863" /db_xref="UniProtKB/Swiss-Prot:P71054" /translation="MNSGPKVSVIMGIYNCERTLAESIESILSQSYKNWELILCDDAS TDGTLRIAKQYAAHYSDRIKLIQNKTNKRLAASLNHCLSHATGDYIARQDGDDLSFPR RLEKQVAFLEKHRHYQVVGTGMLVFDEFGVRGARILPSVPEPGIMAKGTPFCHGTIMM RASAYRTLKGYRSVRRTRRMEDIDLWLRFFEEGFRGYNLQEALYKVREDSDAFKRRSF TYSIDNAILVYQACRRLKLPLSDYIYIAKPLIRAFMPAAVMNRYHKKRVMNQKEGLVK HE*" gene complement(3390015..3390851) /gene="epsE" /locus_tag="BSU_34330" /old_locus_tag="BSU34330" CDS complement(3390848..3391993) /gene="epsD" /locus_tag="BSU_34340" /old_locus_tag="BSU34340" /EC_number="2.4.-.-" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15175311, 15661000, 23378512, 26299781; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative extracellular matrix glycosyltransferase" /protein_id="NP_391314.1" /db_xref="EnsemblGenomes-Gn:BSU34340" /db_xref="EnsemblGenomes-Tr:CAB15439" /db_xref="GOA:P71053" /db_xref="InterPro:IPR001296" /db_xref="InterPro:IPR028098" /db_xref="SubtiList:BG11862" /db_xref="UniProtKB/Swiss-Prot:P71053" /translation="MTKKILFCATVDYHFKAFHLPYFKWFKQMGWEVHVAANGQTKLP YVDEKFSIPIRRSPFDPQNLAVYRQLKKVIDTYEYDIVHCHTPVGGVLARLAARQARR HGTKVLYTAHGFHFCKGAPMKNWLLYYPVEKWLSAYTDCLITINEEDYIRAKGLQRPG GRTQKIHGIGVNTERFRPVSPIEQQRLREKHGFREDDFILVYPAELNLNKNQKQLIEA AALLKEKIPSLRLVFAGEGAMEHTYQTLAEKLGASAHVCFYGFCSDIHELIQLADVSV ASSIREGLGMNVLEGMAAEQPAIATDNRGHREIIRDGENGFLIKIGDSAAFARRIEQL YHKPELCRKLGQEGRKTALRFSEARTVEEMADIYSAYMDMDTKEKSV*" gene complement(3390848..3391993) /gene="epsD" /locus_tag="BSU_34340" /old_locus_tag="BSU34340" CDS complement(3392005..3393801) /gene="epsC" /locus_tag="BSU_34350" /old_locus_tag="BSU34350" /EC_number="5.1.3.-" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15661000, 23378512, 27655338; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative UDP-sugar epimerase involved in biofilmmatrix formation" /protein_id="NP_391315.1" /db_xref="EnsemblGenomes-Gn:BSU34350" /db_xref="EnsemblGenomes-Tr:CAB15440" /db_xref="GOA:P71052" /db_xref="InterPro:IPR003869" /db_xref="InterPro:IPR029063" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG11861" /db_xref="UniProtKB/Swiss-Prot:P71052" /translation="MIIALDTYLVLNSVIAGYQFLKDSYQFYDSGALLLTAVSLLLSY HVCAFLFNQYKQVWTYTGLGELIVLLKGITLSAAVTGVIQYAVYHTMFFRLLTACWVL QLLSIGGTRILSRVLNESIRKKRCASSRALIIGAGSGGTLMVRQLLSKDEPDIIPVAF IDDDQTKHKLEIMGLPVIGGKESIMPAVQKLKINYIIIAIPSLRTHELQVLYKECVRT GVSIKIMPHFDEMLLGTRTAGQIRDVKAEDLLGRKPVTLDTSEISNRIKGKTVLVTGA GGSIGSEICRQISAFQPKEIILLGHGENSIHSIYTELNGRFGKHIVFHTEIADVQDRD KMFTLMKKYEPHVVYHAAAHKHVPLMEHNPEEAVKNNIIGTKNVAEAADMSGTETFVL ISSDKAVNPANVMGATKRFAEMIIMNLGKVSRTKFVAVRFGNVLGSRGSVIPIFKKQI EKGGPVTVTHPAMTRYFMTIPEASRLVIQAGALAKGRQIFVLDMGEPVKIVDLAKNLI HLSGYTTEQVPIEFTGIRPGEKMYEELLNKNEVHAEQIFPKIHIGKAVDGDWPVLMRF IEDFHELPEADLRARLFAAINTSEEMTAASVH*" gene complement(3392005..3393801) /gene="epsC" /locus_tag="BSU_34350" /old_locus_tag="BSU34350" S_feature complement(3393802..3393861) /Source="Nicolas_S_feature" /locus_tag="new_3528204_3528263_c" /HighExp="LoTm, G/S, M9-tran, BMM, MG 150, S3, S2, S4, aero, T0.30H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigD" /TUshortPSig="0.79" /TUlongSig="NA" /TUlongPSig="NA" /label="S1312" promotor_-10 complement(3393835..3393853) /Source="Nicolas_upshift_promotors" /id="U2699" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp="0.79020979020979" /psig="0.79020979020979" /xcortree=2767 /SigmaFactorBS="atacataggacgtattgtcggtttagctgctgccgatttttt ggagagACGAAAAccgccgcagctaaACCGATAAAAGAATTAGGGgggaaaaggttga g" /listShort="S1312, epsC, epsD, epsE, epsF, epsG, epsH" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3393861) /Source="Nicolas_upshifts" /id="U2699" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp="0.79020979020979" /psig="0.79020979020979" /xcortree=2767 /SigmaFactorBS="atacataggacgtattgtcggtttagctgctgccgatttttt ggagagACGAAAAccgccgcagctaaACCGATAAAAGAATTAGGGgggaaaaggttga g" /listShort="S1312, epsC, epsD, epsE, epsF, epsG, epsH" /GFF_Attribute="listLong" promotor_-35 complement(3393867..3393873) /Source="Nicolas_upshift_promotors" /id="U2699" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp="0.79020979020979" /psig="0.79020979020979" /xcortree=2767 /SigmaFactorBS="atacataggacgtattgtcggtttagctgctgccgatttttt ggagagACGAAAAccgccgcagctaaACCGATAAAAGAATTAGGGgggaaaaggttga g" /listShort="S1312, epsC, epsD, epsE, epsF, epsG, epsH" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3394060..3394743) /gene="epsB" /locus_tag="BSU_34360" /old_locus_tag="BSU34360" /EC_number="2.7.10.2" /function="16.3: Control" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:15661000, 15741737, 24493247, 26283769, 28950882" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15661000, 15741737, 24493247, 26283769, 28950882; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="protein tyrosine kinase involved in biofilm matrix formation" /protein_id="NP_391316.1" /db_xref="EnsemblGenomes-Gn:BSU34360" /db_xref="EnsemblGenomes-Tr:CAB15441" /db_xref="GOA:P71051" /db_xref="InterPro:IPR005702" /db_xref="InterPro:IPR025669" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG11860" /db_xref="UniProtKB/Swiss-Prot:P71051" /translation="MIFRKKKARRGLAQISVLHNKSVVAEQYRTIRTNIEFSSVQTNL RSILVTSSVPGEGKSFSAANLAAVFAQQQEKKVLLVDADLRKPTINQTFQVDNVTGLT NVLVGNASLSETVQKTPIDNLYVLTSGPTPPNPAELLSSKAMGDLISEIYEQFSLVIF DSPPLLAVADAQILANQTDGSVLVVLSGKTKTDTVLKAKDALEQSNAKLLGALLNKKK MKKSEHYSY*" gene complement(3394060..3394743) /gene="epsB" /locus_tag="BSU_34360" /old_locus_tag="BSU34360" CDS complement(3394749..3395453) /gene="epsA" /locus_tag="BSU_34370" /old_locus_tag="BSU34370" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2b: Function from indirect experimental evidences (e.g. phenotypes); PubMedId: 12970183, 15661000, 23378512, 26283769, 28950882; Product type r : regulator" /codon_start=1 /transl_table=11 /product="modulator of protein tyrosine kinase EpsB involved in biofilm matrix formation" /protein_id="NP_391317.1" /db_xref="EnsemblGenomes-Gn:BSU34370" /db_xref="EnsemblGenomes-Tr:CAB15442" /db_xref="GOA:P71050" /db_xref="InterPro:IPR003856" /db_xref="SubtiList:BG11859" /db_xref="UniProtKB/Swiss-Prot:P71050" /translation="MNENMSFKELYAIVRHRFVLILLITIGVTLIMGFVQFKVISPTY QASTQVLVHESDGEENSNLSDIQRNLQYSSTFQSIMKSTALMEEVKAELHLSESASSL KGKVVTSSENESEIINVAVQDHDPAKAAEIANTLVNKFEKEVDERMNVQGVHILSEAK ASESPMIKPARLRNMVMAFGAAVMGGITLAFFLHFLDDTCKSARQLSERTGLPCLGSV PDVHKGRNRGIKHFGE*" gene complement(3394749..3395453) /gene="epsA" /locus_tag="BSU_34370" /old_locus_tag="BSU34370" promotor_-35 3395418 /Source="Nicolas_upshift_promotors" /id="U2700" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.995004995004995" /psig="0.995004995004995" /xcortree=1024 /SigmaFactorBS="cgattgtgatgagcagaatcagcacgaatctgtgtctgacaa tCgcatataattctttgaaacTCATATTCTCATTCATGTAttcatagccttcagcctt c" /listShort="slrR" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 3395435 /Source="Nicolas_upshifts" /id="U2700" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.995004995004995" /psig="0.995004995004995" /xcortree=1024 /SigmaFactorBS="cgattgtgatgagcagaatcagcacgaatctgtgtctgacaa tCgcatataattctttgaaacTCATATTCTCATTCATGTAttcatagccttcagcctt c" /listShort="slrR" /GFF_Attribute="listLong" promotor_-10 3395438..3395456 /Source="Nicolas_upshift_promotors" /id="U2700" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.995004995004995" /psig="0.995004995004995" /xcortree=1024 /SigmaFactorBS="cgattgtgatgagcagaatcagcacgaatctgtgtctgacaa tCgcatataattctttgaaacTCATATTCTCATTCATGTAttcatagccttcagcctt c" /listShort="slrR" /GFF_Attribute="listLong" /label="promotor_-10" S_feature complement(3395454..3395511) /Source="Nicolas_S_feature" /locus_tag="new_3529856_3529913_c" /HighExp="LoTm, BT, S3, G/S, BMM, M9-tran, S4, aero, T1.0H, Cold" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.952" /TUlongSig="NA" /TUlongPSig="NA" /label="S1313" promotor_-10 complement(3395507..3395526) /Source="Nicolas_upshift_promotors" /id="U2701" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.441558441558442" /psig="0.952047952047952" /xcortree=2770 /SigmaFactorBS="aagagaacttattggcttattttgcAATTTTTAaataataac gtttTCTTTTATAATCCAATCATTaacagaaaggggcgcgggaagccagccgcgggaa g" /listShort="S1313, epsA, epsB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3395512) /Source="Nicolas_upshifts" /id="U2701" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.441558441558442" /psig="0.952047952047952" /xcortree=2770 /SigmaFactorBS="aagagaacttattggcttattttgcAATTTTTAaataataac gtttTCTTTTATAATCCAATCATTaacagaaaggggcgcgggaagccagccgcgggaa g" /listShort="S1313, epsA, epsB" /GFF_Attribute="listLong" promotor_-35 complement(3395540..3395547) /Source="Nicolas_upshift_promotors" /id="U2701" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.441558441558442" /psig="0.952047952047952" /xcortree=2770 /SigmaFactorBS="aagagaacttattggcttattttgcAATTTTTAaataataac gtttTCTTTTATAATCCAATCATTaacagaaaggggcgcgggaagccagccgcgggaa g" /listShort="S1313, epsA, epsB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 3395629..3395634 /Source="Nicolas_upshift_promotors" /id="U2702" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.464535464535465" /psig="0.995004995004995" /xcortree=2771 /SigmaFactorBS="cctctaatttactgcacttcccttattattttaaATTTTAta aagaacgaaaaaTTCCTTATAATGAACGAAATaacgacaggaatagaggagaatttca t" /listShort="slrR" /listLong="pnbA" /label="promotor_-35" promotor_-10 3395649..3395668 /Source="Nicolas_upshift_promotors" /id="U2702" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.464535464535465" /psig="0.995004995004995" /xcortree=2771 /SigmaFactorBS="cctctaatttactgcacttcccttattattttaaATTTTAta aagaacgaaaaaTTCCTTATAATGAACGAAATaacgacaggaatagaggagaatttca t" /listShort="slrR" /listLong="pnbA" /label="promotor_-10" upshifts 3395655 /Source="Nicolas_upshifts" /id="U2702" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.464535464535465" /psig="0.995004995004995" /xcortree=2771 /SigmaFactorBS="cctctaatttactgcacttcccttattattttaaATTTTAta aagaacgaaaaaTTCCTTATAATGAACGAAATaacgacaggaatagaggagaatttca t" /listShort="slrR" /listLong="pnbA" CDS 3395699..3396157 /gene="slrR" /locus_tag="BSU_34380" /old_locus_tag="BSU34380" /function="16.5: Explore" /function="16.13: Shape" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:18430133, 18647168, 20923420, 28546427" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 18430133, 18647168, 20923420, 28546427; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator of autolysin genes (biofilm formation)" /protein_id="NP_391318.1" /db_xref="EnsemblGenomes-Gn:BSU34380" /db_xref="EnsemblGenomes-Tr:CAB15443" /db_xref="GOA:P71049" /db_xref="InterPro:IPR001387" /db_xref="InterPro:IPR010981" /db_xref="InterPro:IPR010982" /db_xref="InterPro:IPR036281" /db_xref="SubtiList:BG11858" /db_xref="UniProtKB/Swiss-Prot:P71049" /translation="MIGRIIRLYRKRKGYSINQLAVESGVSKSYLSKIERGVHTNPSV QFLKKVSATLEVELTELFDAETMMYEKISGGEEEWRVHLVQAVQAGMEKEELFTFTNR LKKEQPETASYRNRKLTESNIEEWKALMAEAREIGLSVHEVKSFLKTKGR*" gene 3395699..3396157 /gene="slrR" /locus_tag="BSU_34380" /old_locus_tag="BSU34380" promotor_-35 3396179..3396182 /Source="Nicolas_upshift_promotors" /id="U2703" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.446553446553447" /psig="0.888111888111888" /xcortree=3178 /SigmaFactorBS="aaatcctttttaaaaacaaagggaagatgatgatcggttaaa gggctaacgTTCGcatctataggggaaatCTGTTTATAATGGGGGAAAaagggagaga a" /listShort="pnbA" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 3396188 /Source="Nicolas_upshifts" /id="U2703" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.446553446553447" /psig="0.888111888111888" /xcortree=3178 /SigmaFactorBS="aaatcctttttaaaaacaaagggaagatgatgatcggttaaa gggctaacgTTCGcatctataggggaaatCTGTTTATAATGGGGGAAAaagggagaga a" /listShort="pnbA" /GFF_Attribute="listLong" promotor_-10 3396199..3396217 /Source="Nicolas_upshift_promotors" /id="U2703" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.446553446553447" /psig="0.888111888111888" /xcortree=3178 /SigmaFactorBS="aaatcctttttaaaaacaaagggaagatgatgatcggttaaa gggctaacgTTCGcatctataggggaaatCTGTTTATAATGGGGGAAAaagggagaga a" /listShort="pnbA" /GFF_Attribute="listLong" /label="promotor_-10" CDS 3396233..3397702 /gene="pnbA" /locus_tag="BSU_34390" /old_locus_tag="BSU34390" /EC_number="3.1.1.1" /function="16.11: Scavenge (Catabolism)" /function="16.6: Maintain" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:7828905, 15138843" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7828905, 15138843; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="para-nitrobenzyl esterase (intracellular esterase B)" /protein_id="NP_391319.1" /db_xref="EnsemblGenomes-Gn:BSU34390" /db_xref="EnsemblGenomes-Tr:CAB15444" /db_xref="GOA:P37967" /db_xref="InterPro:IPR000997" /db_xref="InterPro:IPR002018" /db_xref="InterPro:IPR019819" /db_xref="InterPro:IPR019826" /db_xref="InterPro:IPR029058" /db_xref="PDB:1C7I" /db_xref="PDB:1C7J" /db_xref="PDB:1QE3" /db_xref="SubtiList:BG11844" /db_xref="UniProtKB/Swiss-Prot:P37967" /translation="MTHQIVTTQYGKVKGTTENGVHKWKGIPYAKPPVGQWRFKAPEP PEVWEDVLDATAYGSICPQPSDLLSLSYTELPRQSEDCLYVNVFAPDTPSKNLPVMVW IHGGAFYLGAGSEPLYDGSKLAAQGEVIVVTLNYRLGPFGFLHLSSFNEAYSDNLGLL DQAAALKWVRENISAFGGDPDNVTVFGESAGGMSIAALLAMPAAKGLFQKAIMESGAS RTMTKEQAASTSAAFLQVLGINEGQLDKLHTVSAEDLLKAADQLRIAEKENIFQLFFQ PALDPKTLPEEPEKAIAEGAASGIPLLIGTTRDEGYLFFTPDSDVHSQETLDAALEYL LGKPLAEKVADLYPRSLESQIHMMTDLLFWRPAVAYASAQSHYAPVWMYRFDWHPKKP PYNKAFHALELPFVFGNLDGLERMAKAEITDEVKQLSHTIQSAWITFAKTGNPSTEAV NWPAYHEETRETLILDSEITIENDPESEKRQKLFPSKGE*" gene 3396233..3397702 /gene="pnbA" /locus_tag="BSU_34390" /old_locus_tag="BSU34390" downshifts 3397679 /Source="Nicolas_upshifts" /id="D1780" /incds=0 /nref=4 /ntot=150 /MaxReadThrough="3.66738" /MaxDrop="2.70933" /score="-9.70074934" /energy="-12.2" /TU="U2703" /idTUdmin="U2703" /TUdmin="-198" /isTUend="FALSE" CDS 3397705..3397896 /locus_tag="BSU_34399" /old_locus_tag="BSU34399" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_009514003.1" /translation="MGKTGYIGAAIVVAACIIILSAVVCLRDTVYYQPMRWTGIILFF AGIVMVPAYSAKRKPGKEK*" gene 3397705..3397896 /locus_tag="BSU_34399" /old_locus_tag="BSU34399" downshifts 3397875 /Source="Nicolas_upshifts" /id="D1781" /incds=0 /nref=24 /ntot=181 /MaxReadThrough="-0.096" /MaxDrop="4.20686" /score="34.8993337" /energy="-22.3" /TU="NA" /idTUdmin="U2703" /TUdmin="-2" /isTUend="TRUE" CDS complement(3397923..3398408) /gene="padC" /locus_tag="BSU_34400" /old_locus_tag="BSU34400" /EC_number="4.1.1.102" /EC_number="4.1.1.-" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:9546183, 12903944, 17295427, 18326577, 21685295, 26658822" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9546183, 12903944, 17295427, 18326577, 21685295, 26658822; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="phenolic acid decarboxylase" /protein_id="NP_391320.1" /db_xref="EnsemblGenomes-Gn:BSU34400" /db_xref="EnsemblGenomes-Tr:CAB15445" /db_xref="GOA:O07006" /db_xref="InterPro:IPR008729" /db_xref="InterPro:IPR012674" /db_xref="PDB:2P8G" /db_xref="PDB:4ALB" /db_xref="SubtiList:BG12433" /db_xref="UniProtKB/Swiss-Prot:O07006" /translation="MENFIGSHMIYTYENGWEYEIYIKNDHTIDYRIHSGMVAGRWVR DQEVNIVKLTEGVYKVSWTEPTGTDVSLNFMPNEKRMHGIIFFPKWVHEHPEITVCYQ NDHIDLMKESREKYETYPKYVVPEFAEITFLKNEGVDNEEVISKAPYEGMTDDIRAGR L*" gene complement(3397923..3398408) /gene="padC" /locus_tag="BSU_34400" /old_locus_tag="BSU34400" CDS complement(3398431..3398742) /gene="yveG" /locus_tag="BSU_34410" /old_locus_tag="BSU34410" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /pseudo /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /db_xref="EnsemblGenomes-Gn:BSU34410" /db_xref="EnsemblGenomes-Tr:CAB15446" /db_xref="GOA:O07005" /db_xref="InterPro:IPR011250" /db_xref="InterPro:IPR020915" /db_xref="PSEUDO:CAB15446.2" /db_xref="SubtiList:BG12432" /db_xref="UniProtKB/Swiss-Prot:O07005" /translation="MPGGADSQMIRANGRTDLSARYVIETADHELIYIENNGIRQVSK PFRKQAAAGEIIEPEHVYFRTVPTFETGSEVYQWLHDRLFIGSAERTPDYVLLDIYEV Q*" gene complement(3398431..3398742) /gene="yveG" /locus_tag="BSU_34410" /old_locus_tag="BSU34410" /pseudo CDS complement(3398794..3398886) /gene="yveF" /locus_tag="BSU_34420" /old_locus_tag="BSU34420" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /pseudo /codon_start=1 /transl_table=11 /product="hypothetical protein" /db_xref="EnsemblGenomes-Gn:BSU34420" /db_xref="EnsemblGenomes-Tr:CAB15447" /db_xref="PSEUDO:CAB15447.1" /db_xref="SubtiList:BG12431" /db_xref="UniProtKB/Swiss-Prot:O07004" /translation="MKKPVLKPFASLEIKVDPPITIGETSLGLR*" gene complement(3398794..3398886) /gene="yveF" /locus_tag="BSU_34420" /old_locus_tag="BSU34420" /pseudo promotor_-10 complement(3398926..3398945) /Source="Nicolas_upshift_promotors" /id="U2704" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.66033966033966" /psig=1 /xcortree=3185 /SigmaFactorBS="ctgtcttcaaacagtccttgtttttttatgttcctatTGTTT GACagttaactgcaatGGTGTTAAAGTGAACATGTAaatagttacatgattttttctg a" /listShort="yveF, yveG, padC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3398943) /Source="Nicolas_upshifts" /id="U2704" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.66033966033966" /psig=1 /xcortree=3185 /SigmaFactorBS="ctgtcttcaaacagtccttgtttttttatgttcctatTGTTT GACagttaactgcaatGGTGTTAAAGTGAACATGTAaatagttacatgattttttctg a" /listShort="yveF, yveG, padC" /GFF_Attribute="listLong" promotor_-35 complement(3398959..3398966) /Source="Nicolas_upshift_promotors" /id="U2704" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.66033966033966" /psig=1 /xcortree=3185 /SigmaFactorBS="ctgtcttcaaacagtccttgtttttttatgttcctatTGTTT GACagttaactgcaatGGTGTTAAAGTGAACATGTAaatagttacatgattttttctg a" /listShort="yveF, yveG, padC" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3399017..3399700) /gene="racX" /locus_tag="BSU_34430" /old_locus_tag="BSU34430" /EC_number="5.1.1.-" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:9987136, 19063962, 2054383, 28894939" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9987136, 19063962, 2054383, 28894939; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="promiscuous aminoacid racemase (prefers arginine, lysine and ornithine)" /protein_id="NP_391323.1" /db_xref="EnsemblGenomes-Gn:BSU34430" /db_xref="EnsemblGenomes-Tr:CAB15448" /db_xref="GOA:P32960" /db_xref="InterPro:IPR001920" /db_xref="InterPro:IPR004380" /db_xref="InterPro:IPR015942" /db_xref="InterPro:IPR018187" /db_xref="InterPro:IPR033134" /db_xref="SubtiList:BG10391" /db_xref="UniProtKB/Swiss-Prot:P32960" /translation="MIGILAGMGPKSTSPFIDKVIDYCQKLYGASNDIDYPHMMIYSC PTPFYADRPIDHDEMKKAIIDGAVKLEKTGVDFIALPCNTAHVYYEEIQQALSVPMLH IVEETIKEIPHPAKKAVVLGTEPTIQSAIYQKVLKGNGQEVIHKDHWQQAVNQLIAAI KQPNHMQHTQALWQTLYEEISQHADIIISACTDLNAVLDHIQSEIPIIDSSACLAKST VSTYLAYQS*" gene complement(3399017..3399700) /gene="racX" /locus_tag="BSU_34430" /old_locus_tag="BSU34430" downshifts complement(3399035) /Source="Nicolas_upshifts" /id="D1782" /incds=0 /nref=122 /ntot=223 /MaxReadThrough="3.49026" /MaxDrop="5.32077" /score="5.15607483" /energy="-9.3" /TU="U2705" /idTUdmin="U2704" /TUdmin="-708" /isTUend="FALSE" CDS complement(3399716..3401071) /gene="pbpE" /locus_tag="BSU_34440" /old_locus_tag="BSU34440" /function="16.6: Maintain" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:7592498, 9987136, 12533473, 14679248, 19063962" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7592498, 9987136, 12533473, 14679248, 19063962; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="penicillin-binding protein 4*" /protein_id="NP_391324.1" /db_xref="EnsemblGenomes-Gn:BSU34440" /db_xref="EnsemblGenomes-Tr:CAB15449" /db_xref="GOA:P32959" /db_xref="InterPro:IPR001466" /db_xref="InterPro:IPR012338" /db_xref="InterPro:IPR021860" /db_xref="SubtiList:BG10390" /db_xref="UniProtKB/Swiss-Prot:P32959" /translation="MKQNKRKHLQTLFETLGEKHQFNGTVLAAEGGDILYHHSFGYAE MTEKRPLKTNSLFELASLSKPFTALGIILLEEKGILGYEDKVDRWLPGFPYQGVTIRH LLNHTSGLPDYMGWFFANWDSHKIAVNQDIVDMLMNEGLSGYFEPNEGWMYSNTGYVL LAVIIEKASGMSYADFIKTSIFLPAGMNETRVYNRRLSPERIDHYAYGYVYDVHSETY VLPDELEETNYVVYLDGIQGDGTVNSVTSDLFRFDQALYQDDFISKASKESAFSPVRL NNGETIDYGFGWVLQNSPEKGRIVSHSGGWPGYSTMMIRYIDHRKTLIYLSNKEEDTE YEQAILKAAEHILFGQPYDVPERPADKKKKAIDTAIYSRYVGSYLLQDGTAAQVTTEN ERLYLEIAGQLRLELFPSSETRFFLRALSVEVEFTLGEDAAKSFILYEDGSEEEAVRT K*" gene complement(3399716..3401071) /gene="pbpE" /locus_tag="BSU_34440" /old_locus_tag="BSU34440" promotor_-10 complement(3401083..3401098) /Source="Nicolas_upshift_promotors" /id="U2705" /multdbtbs="SigW" /comp="M9" /sig="SigWXY" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=1687 /SigmaFactorBS="gttaaaaaggatctctaactgaaggatttttcaaaatattTG AAACGTTAgtaggttagtaACGTACAGAGATATGGgaggtggaggaatgaagcagaat a" /listShort="pbpE, racX, yveF, yveG, padC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3401099) /Source="Nicolas_upshifts" /id="U2705" /multdbtbs="SigW" /comp="M9" /sig="SigWXY" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=1687 /SigmaFactorBS="gttaaaaaggatctctaactgaaggatttttcaaaatattTG AAACGTTAgtaggttagtaACGTACAGAGATATGGgaggtggaggaatgaagcagaat a" /listShort="pbpE, racX, yveF, yveG, padC" /GFF_Attribute="listLong" promotor_-35 complement(3401110..3401119) /Source="Nicolas_upshift_promotors" /id="U2705" /multdbtbs="SigW" /comp="M9" /sig="SigWXY" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=1687 /SigmaFactorBS="gttaaaaaggatctctaactgaaggatttttcaaaatattTG AAACGTTAgtaggttagtaACGTACAGAGATATGGgaggtggaggaatgaagcagaat a" /listShort="pbpE, racX, yveF, yveG, padC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 3401373..3401380 /Source="Nicolas_upshift_promotors" /id="U2706" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.865134865134865" /psig="0.998001998001998" /xcortree=1753 /SigmaFactorBS="ttatgattttctatcaaacaaaagaggaaaatagacCAGTTG CAatccaaacgagagTCTAATAGAATGAGGTCGAAaagtaaatcgcgcgggtttgtta c" /listShort="S1314, sacB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3401394..3401413 /Source="Nicolas_upshift_promotors" /id="U2706" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.865134865134865" /psig="0.998001998001998" /xcortree=1753 /SigmaFactorBS="ttatgattttctatcaaacaaaagaggaaaatagacCAGTTG CAatccaaacgagagTCTAATAGAATGAGGTCGAAaagtaaatcgcgcgggtttgtta c" /listShort="S1314, sacB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3401397 /Source="Nicolas_upshifts" /id="U2706" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.865134865134865" /psig="0.998001998001998" /xcortree=1753 /SigmaFactorBS="ttatgattttctatcaaacaaaagaggaaaatagacCAGTTG CAatccaaacgagagTCTAATAGAATGAGGTCGAAaagtaaatcgcgcgggtttgtta c" /listShort="S1314, sacB" /GFF_Attribute="listLong" S_feature 3401419..3401609 /Source="Nicolas_S_feature" /locus_tag="new_3535821_3536011" /HighExp="G150, G180, G135, LBGexp, Mt0, Lbexp, LBGtran, dia0, GM 150, MG 60" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.219024" /TUshortSig="SigA" /TUshortPSig="0.998" /TUlongSig="NA" /TUlongPSig="NA" /label="S1314" CDS 3401610..3403031 /gene="sacB" /locus_tag="BSU_34450" /old_locus_tag="BSU34450" /EC_number="2.4.1.10" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:1400159, 11200435, 11320136, 11739774, 17704766, 15528654, 26600431" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1400159, 11200435, 11320136, 11739774, 17704766, 15528654, 26600431; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="levansucrase; levanase (moonlighting)" /protein_id="NP_391325.1" /db_xref="EnsemblGenomes-Gn:BSU34450" /db_xref="EnsemblGenomes-Tr:CAB15450" /db_xref="GOA:P05655" /db_xref="InterPro:IPR003469" /db_xref="InterPro:IPR023296" /db_xref="PDB:1OYG" /db_xref="PDB:1PT2" /db_xref="PDB:2VDT" /db_xref="PDB:3BYJ" /db_xref="PDB:3BYK" /db_xref="PDB:3BYL" /db_xref="PDB:3BYN" /db_xref="SubtiList:BG10388" /db_xref="UniProtKB/Swiss-Prot:P05655" /translation="MNIKKFAKQATVLTFTTALLAGGATQAFAKETNQKPYKETYGIS HITRHDMLQIPEQQKNEKYQVPEFDSSTIKNISSAKGLDVWDSWPLQNADGTVANYHG YHIVFALAGDPKNADDTSIYMFYQKVGETSIDSWKNAGRVFKDSDKFDANDSILKDQT QEWSGSATFTSDGKIRLFYTDFSGKHYGKQTLTTAQVNVSASDSSLNINGVEDYKSIF DGDGKTYQNVQQFIDEGNYSSGDNHTLRDPHYVEDKGHKYLVFEANTGTEDGYQGEES LFNKAYYGKSTSFFRQESQKLLQSDKKRTAELANGALGMIELNDDYTLKKVMKPLIAS NTVTDEIERANVFKMNGKWYLFTDSRGSKMTIDGITSNDIYMLGYVSNSLTGPYKPLN KTGLVLKMDLDPNDVTFTYSHFAVPQAKGNNVVITSYMTNRGFYADKQSTFAPSFLLN IKGKKTSVVKDSILEQGQLTVNK*" gene 3401610..3403031 /gene="sacB" /locus_tag="BSU_34450" /old_locus_tag="BSU34450" downshifts 3403025 /Source="Nicolas_upshifts" /id="D1783" /incds=0 /nref=2 /ntot=27 /MaxReadThrough="2.33324" /MaxDrop="3.39023" /score="9.57663013" /energy="-7.7" /TU="NA" /idTUdmin="U2706" /TUdmin=0 /isTUend="TRUE" CDS 3403105..3404655 /gene="levB" /locus_tag="BSU_34460" /old_locus_tag="BSU34460" /EC_number="3.2.1.64" /function="16.11: Scavenge (Catabolism)" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:11739774, 15528654, 26773563" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11739774, 15528654, 26773563; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="endolevanase, selectively cleaves the (beta-2,6)fructosyl bonds" /protein_id="NP_391326.1" /db_xref="EnsemblGenomes-Gn:BSU34460" /db_xref="EnsemblGenomes-Tr:CAB15451" /db_xref="GOA:O07003" /db_xref="InterPro:IPR001362" /db_xref="InterPro:IPR013148" /db_xref="InterPro:IPR013189" /db_xref="InterPro:IPR013320" /db_xref="InterPro:IPR023296" /db_xref="SubtiList:BG12430" /db_xref="UniProtKB/Swiss-Prot:O07003" /translation="MNYIKAGKWLTVFLTFLGILLFIDLFPKEEHDQKTKSKQKPDYR AAYHFTTPDKWKNDPQKPIYFDGKYHYFYLYNRDYPKGNGTEWRHAVSEDLVHWTDEG VAIPKYTNPDGDIWTGSVVVDKENTAGFGKNALVAIVTQPSAKDKKQEQYLWYSTDKG KSFKFYSGNPVMPNPGTDDFRDPKVIWDDQDNKWVMVMAEGSKIGFYESDNLKDWHYT SGFFPEQAGMVECPDLYMMRASDGTNKWVLGASANGKPWGKPNTYAYWTGSFDGKEFK ADQTEAQWLDYGFDWYGGVTFEDSKSTDPLEKRYALAWMNNWDYANNTPTMKNGFNGT DSVIRELRLKEQDGTYSLVSQPIEALEQLTVSTDEIEDQDVNGSKTLSITGDTYQLDT DLSWSELKNAGVRLRESEDQKRHIDVGIFAEGGYAYVNRAATNQPDKSNTYVESKAPY DVNKRKVHLKILVDKTTIEVFVGDGKTVFSNEVFPKPEDKGITLYSDGGTASFKNITV KHFDSIHE*" gene 3403105..3404655 /gene="levB" /locus_tag="BSU_34460" /old_locus_tag="BSU34460" promotor_-35 3404699..3404705 /Source="Nicolas_upshift_promotors" /id="U2707" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp="0.992007992007992" /psig="0.992007992007992" /xcortree=926 /SigmaFactorBS="caggggcggcgcaggctgcccctgtttttttattaggagcGG TATTCtctgttacatattGGGCATTGTAAGgaatataaggctggtttcaaaggaggaa g" /listShort="yveA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3404719..3404730 /Source="Nicolas_upshift_promotors" /id="U2707" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp="0.992007992007992" /psig="0.992007992007992" /xcortree=926 /SigmaFactorBS="caggggcggcgcaggctgcccctgtttttttattaggagcGG TATTCtctgttacatattGGGCATTGTAAGgaatataaggctggtttcaaaggaggaa g" /listShort="yveA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3404719 /Source="Nicolas_upshifts" /id="U2707" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp="0.992007992007992" /psig="0.992007992007992" /xcortree=926 /SigmaFactorBS="caggggcggcgcaggctgcccctgtttttttattaggagcGG TATTCtctgttacatattGGGCATTGTAAGgaatataaggctggtttcaaaggaggaa g" /listShort="yveA" /GFF_Attribute="listLong" CDS 3404763..3406325 /gene="aspP" /locus_tag="BSU_34470" /old_locus_tag="BSU34470" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:12730183, 15528654, 15849754, 16850406" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12730183, 15528654, 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="L-aspartate/L-glutamate / proton permease" /protein_id="NP_391327.1" /db_xref="EnsemblGenomes-Gn:BSU34470" /db_xref="EnsemblGenomes-Tr:CAB15452" /db_xref="GOA:O07002" /db_xref="InterPro:IPR002293" /db_xref="SubtiList:BG12429" /db_xref="UniProtKB/Swiss-Prot:O07002" /translation="MSKQGNFQKSMSLFDLILIGMGAIFGSAWLFAVSNVASKAGPSG AFSWILGGAIILLIGLVYAELGAALPRTGGIIRYPVYSHGHLVGYLISFVTIVAYTSL ISIEVTAVRQYVAYWFPGLTIKGSDSPTISGWILQFALLCLFFLLNYWSVKTFAKANF IISIFKYIVPITIIIVLIFHFQPENLSVQGFAPFGFTGIQAAISTGGVMFAYLGLHPI VSVAGEVQNPKRNIPIALIICIIVSTIIYTVLQVTFIGAIPTETLKHGWPAIGREFSL PFKDIAVMLGLGWLATLVILDAILSPGGNGNIFMNTTSRLVYAWARNGTLFGIFSKVN KDTGTPRASLWLSFALSIFWTLPFPSWNALVNVCSVALILSYAIAPISSAALRVNAKD LNRPFYLKGMSIIGPLSFIFTAFIVYWSGWKTVSWLLGSQLVMFLIYLCFSKYTPKED VSLAQQLKSAWWLIGFYIMMLIFSYIGSFGHGLGIISNPVDLILVAIGSLAIYYWAKY TGLPKAAIDYDK*" gene 3404763..3406325 /gene="aspP" /locus_tag="BSU_34470" /old_locus_tag="BSU34470" downshifts 3406303 /Source="Nicolas_upshifts" /id="D1784" /incds=0 /nref=12 /ntot=29 /MaxReadThrough="1.71122" /MaxDrop="3.47798" /score="-0.444529447" /energy="-11.7" /TU="NA" /idTUdmin="U2707" /TUdmin=0 /isTUend="TRUE" CDS 3406315..3407004 /gene="yvdT" /locus_tag="BSU_34480" /old_locus_tag="BSU34480" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative transcriptional regulator (TetR/AcrR family)" /protein_id="NP_391328.2" /db_xref="EnsemblGenomes-Gn:BSU34480" /db_xref="EnsemblGenomes-Tr:CAB15453" /db_xref="GOA:O07001" /db_xref="InterPro:IPR001647" /db_xref="InterPro:IPR009057" /db_xref="InterPro:IPR036271" /db_xref="PDB:2F07" /db_xref="SubtiList:BG12428" /db_xref="UniProtKB/Swiss-Prot:O07001" /translation="MINKEARGFLASLFFTNKHTRDKMNESQSLLEVFLMPKQTSGKY EKILQAAIEVISEKGLDKASISDIVKKAGTAQGTFYLYFSSKNALIPAIAENLLTHTL DQIKGRLHGDEDFWTVLDILIDETFLITERHKDIIVLCYSGLAIDHSMEKWETIYQPY YSWLEKIINKAIANHEVTEGINSKWTARTIINLVENTAERFYIGFEQDENVEVYKKEI FTFLKRSLGTA*" gene 3406315..3407004 /gene="yvdT" /locus_tag="BSU_34480" /old_locus_tag="BSU34480" promotor_-35 3406354..3406361 /Source="Nicolas_upshift_promotors" /id="U2708" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.573426573426573" /psig="0.999000999001" /xcortree=2082 /SigmaFactorBS="aaagaagcaagaggttttcttgcttctttaTTCTTTACaaac aaacatacaCGCGATAAAATGAATGAGAGtcagtcattactggaggtgttcctcatgc c" /listShort="yvdT, yvdS, yvdR, S1315" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3406375..3406394 /Source="Nicolas_upshift_promotors" /id="U2708" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.573426573426573" /psig="0.999000999001" /xcortree=2082 /SigmaFactorBS="aaagaagcaagaggttttcttgcttctttaTTCTTTACaaac aaacatacaCGCGATAAAATGAATGAGAGtcagtcattactggaggtgttcctcatgc c" /listShort="yvdT, yvdS, yvdR, S1315" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3406384 /Source="Nicolas_upshifts" /id="U2708" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.573426573426573" /psig="0.999000999001" /xcortree=2082 /SigmaFactorBS="aaagaagcaagaggttttcttgcttctttaTTCTTTACaaac aaacatacaCGCGATAAAATGAATGAGAGtcagtcattactggaggtgttcctcatgc c" /listShort="yvdT, yvdS, yvdR, S1315" /GFF_Attribute="listLong" downshifts 3406985 /Source="Nicolas_upshifts" /id="D1785" /incds=0 /nref=189 /ntot=242 /MaxReadThrough="4.85194" /MaxDrop="4.84113" /score="-0.444529447" /energy="-11.7" /TU="U2708" /idTUdmin="U2707" /TUdmin=682 /isTUend="FALSE" downshifts complement(3407083) /Source="Nicolas_upshifts" /id="D1786" /incds=0 /nref=1 /ntot=8 /MaxReadThrough="0.8852" /MaxDrop="3.45447" /score="0.398849185" /energy="-11.7" /TU="NA" /idTUdmin="U2709" /TUdmin=704 /isTUend="FALSE" CDS 3407086..3407421 /gene="psmA" /locus_tag="BSU_34490" /old_locus_tag="BSU34490" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 22978536; Product type t : transporter" /codon_start=1 /transl_table=11 /product="sodium / proton antiporter subunit A" /protein_id="NP_391329.1" /db_xref="EnsemblGenomes-Gn:BSU34490" /db_xref="EnsemblGenomes-Tr:CAB15454" /db_xref="GOA:O32262" /db_xref="InterPro:IPR000390" /db_xref="SubtiList:BG12427" /db_xref="UniProtKB/Swiss-Prot:O32262" /translation="MNWVLVFIAGLLEVVWASSLKHADSLLDWIIIFILIAVSFILLI RSYQKIPMAAAYTVFVGIGTVGTYLTGIVLGESFSAAQMFFLALLLAGILGMKLFTKE SKSQPGGEK*" gene 3407086..3407421 /gene="psmA" /locus_tag="BSU_34490" /old_locus_tag="BSU34490" CDS 3407421..3407741 /gene="psmB" /locus_tag="BSU_34500" /old_locus_tag="BSU34500" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 11160890, 22978536; Product type t: transporter" /codon_start=1 /transl_table=11 /product="sodium-proton two component antiporter subunit" /protein_id="NP_391330.1" /db_xref="EnsemblGenomes-Gn:BSU34500" /db_xref="EnsemblGenomes-Tr:CAB15455" /db_xref="GOA:O06999" /db_xref="InterPro:IPR000390" /db_xref="SubtiList:BG12426" /db_xref="UniProtKB/Swiss-Prot:O06999" /translation="MAWFLLVIAGIEEIIAAIAMKYIDGTRKKWPIIVMTVGFGLSFY CLSQAMIVLPAGVAYAVWTGIGSIGVSAVGLIWFKERFQLSQVISLCLILAGVIGLRL TSSS*" gene 3407421..3407741 /gene="psmB" /locus_tag="BSU_34500" /old_locus_tag="BSU34500" S_feature 3407742..3407932 /Source="Nicolas_S_feature" /locus_tag="new_3542144_3542334" /HighExp="Sw, BC, BI, Lbstat, M0t90, Lbtran, M40t90, H2O2, S8, Paraq" /AntisenseName="yvdQ" /AntisenseCor="3.5547360410813897E-2" /AntisenseRegPval="-0.3" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S1315" CDS complement(3407777..3408289) /gene="yvdQ" /locus_tag="BSU_34510" /old_locus_tag="BSU34510" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_391331.1" /db_xref="EnsemblGenomes-Gn:BSU34510" /db_xref="EnsemblGenomes-Tr:CAB15456" /db_xref="InterPro:IPR012347" /db_xref="InterPro:IPR021617" /db_xref="SubtiList:BG12425" /db_xref="UniProtKB/Swiss-Prot:O06998" /translation="MGILSGNPQDEPMHYGEVFGLWSYVMAGNKMVGNYQMLLNHVGD DDLKKLLRESIEKCQDEIKQVSTILKENGVALPPASPEPPTADLNDIPPGARFLDPDV AASAAAENAAGLVTCSKMMGQSIREDIAMMFGQFHMSKAATGAKYLRLLKNKGWLIPP PLHLQKHHEA*" gene complement(3407777..3408289) /gene="yvdQ" /locus_tag="BSU_34510" /old_locus_tag="BSU34510" downshifts 3407909 /Source="Nicolas_upshifts" /id="D1787" /incds=1 /nref=6 /ntot=39 /MaxReadThrough="1.61612" /MaxDrop="4.65362" /score="0.608596632" /energy="-14.2" /TU="NA" /idTUdmin="U2708" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(3408325..3408336) /Source="Nicolas_upshift_promotors" /id="U2709" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=891 /SigmaFactorBS="tgttttgtttcatttcataaatcttttccgctgaAACATAAa tgttcctccgcttGGGCACGTTATGaaatgtgcaatattgaatatgggaggagaatga g" /listShort="yvdQ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3408331) /Source="Nicolas_upshifts" /id="U2709" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=891 /SigmaFactorBS="tgttttgtttcatttcataaatcttttccgctgaAACATAAa tgttcctccgcttGGGCACGTTATGaaatgtgcaatattgaatatgggaggagaatga g" /listShort="yvdQ" /GFF_Attribute="listLong" promotor_-35 complement(3408351..3408357) /Source="Nicolas_upshift_promotors" /id="U2709" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=891 /SigmaFactorBS="tgttttgtttcatttcataaatcttttccgctgaAACATAAa tgttcctccgcttGGGCACGTTATGaaatgtgcaatattgaatatgggaggagaatga g" /listShort="yvdQ" /GFF_Attribute="listLong" /label="promotor_-35" S_feature complement(3408404..3408540) /Source="Nicolas_S_feature" /locus_tag="new_3542806_3542942_c" /HighExp="BT, S7, S8, S6, B36, G/S, S5, Pyr, G135, S4" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigK" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S1316" downshifts complement(3408447) /Source="Nicolas_upshifts" /id="D1788" /incds=0 /nref=1 /ntot=38 /MaxReadThrough="3.38169" /MaxDrop="2.9968" /score="15.2862513" /energy="-10.3" /TU="U2710" /idTUdmin="U2709" /TUdmin="-660" /isTUend="FALSE" CDS complement(3408541..3409884) /gene="cotNP" /locus_tag="BSU_34520" /old_locus_tag="BSU34520" /EC_number="1.-.-.-" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:12562816" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12562816; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="spore coat protein; putative oxidoreductase" /protein_id="NP_391332.1" /db_xref="EnsemblGenomes-Gn:BSU34520" /db_xref="EnsemblGenomes-Tr:CAB15457" /db_xref="GOA:O06997" /db_xref="InterPro:IPR006094" /db_xref="InterPro:IPR012951" /db_xref="InterPro:IPR016166" /db_xref="InterPro:IPR016167" /db_xref="InterPro:IPR016169" /db_xref="InterPro:IPR036318" /db_xref="SubtiList:BG12424" /db_xref="UniProtKB/Swiss-Prot:O06997" /translation="MGSTQLTGRVIFKGDPGYTEAIKNWNPYVDVYPLVFVFAQNSYD VSNAIKWARENKVPLRVRSGRHALDKNLSVVSGGIVIDVSDMNKVFLDEENAIATVQT GIPVGPLVKGLARDGFMAPFGDSPTVGIGGITMGGGFGVLSRSIGLISDNLLALKTVD AKGRIIHADQSHNEDLLWASRGGGGGNFGYNTQYTFKVHRAPKTATVFNIIWPWEQLE TVFKAWQKWAPFVDERLGCYLEIYSKINGLCHAEGIFLGSKTELIRLLKPLLHAGTPT EADIKTLYYPDAIDFLDPDEPIPGRNDQSVKFSSAWGHDFWSDEPISIMRKFLEDATG TEANFFFINWGGAISRVPKDETAFFWRHPLFYTEWTASWKNKSQEDSNLASVERVRQL MQPYVAGSYVNVPDQNIENFGKEYYGANFARLREIKAKYDPENVFRFPQSIPPSR*" gene complement(3408541..3409884) /gene="cotNP" /locus_tag="BSU_34520" /old_locus_tag="BSU34520" promotor_-10 complement(3409913..3409932) /Source="Nicolas_upshift_promotors" /id="U2710" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1342 /SigmaFactorBS="attatatttatagttcgtagatcatttGTCTATGCGAttatc cagctccTGCATATTTTAGTATCTGAAtcgaatttctttgggagtgaaataatatatg g" /listShort="yvdP, S1316, yvdQ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3409921) /Source="Nicolas_upshifts" /id="U2710" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1342 /SigmaFactorBS="attatatttatagttcgtagatcatttGTCTATGCGAttatc cagctccTGCATATTTTAGTATCTGAAtcgaatttctttgggagtgaaataatatatg g" /listShort="yvdP, S1316, yvdQ" /GFF_Attribute="listLong" promotor_-35 complement(3409945..3409954) /Source="Nicolas_upshift_promotors" /id="U2710" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1342 /SigmaFactorBS="attatatttatagttcgtagatcatttGTCTATGCGAttatc cagctccTGCATATTTTAGTATCTGAAtcgaatttctttgggagtgaaataatatatg g" /listShort="yvdP, S1316, yvdQ" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 3409946..3409951 /Source="Nicolas_upshift_promotors" /id="U2711" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.986013986013986" /psig="0.986013986013986" /xcortree=1039 /SigmaFactorBS="cgattcagatactaaaatatgcaggagctggataatCGCATA gacaaatgatctacgAACTATAAATATAATACGCtaaggcctttttcgtcggtgaggt c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3409967..3409985 /Source="Nicolas_upshift_promotors" /id="U2711" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.986013986013986" /psig="0.986013986013986" /xcortree=1039 /SigmaFactorBS="cgattcagatactaaaatatgcaggagctggataatCGCATA gacaaatgatctacgAACTATAAATATAATACGCtaaggcctttttcgtcggtgaggt c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3409970 /Source="Nicolas_upshifts" /id="U2711" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.986013986013986" /psig="0.986013986013986" /xcortree=1039 /SigmaFactorBS="cgattcagatactaaaatatgcaggagctggataatCGCATA gacaaatgatctacgAACTATAAATATAATACGCtaaggcctttttcgtcggtgaggt c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 3410179..3410188 /Source="Nicolas_upshift_promotors" /id="U2712" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1360 /SigmaFactorBS="aagaaaagagagatgaagaagtgtttagtaccagaggtatac ATCCATACAAcagactctagatcATCATATACTGAATGTATGTagaaaggagacatca g" /listShort="cotR, S1317" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 3410197 /Source="Nicolas_upshifts" /id="U2712" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1360 /SigmaFactorBS="aagaaaagagagatgaagaagtgtttagtaccagaggtatac ATCCATACAAcagactctagatcATCATATACTGAATGTATGTagaaaggagacatca g" /listShort="cotR, S1317" /GFF_Attribute="listLong" promotor_-10 3410202..3410221 /Source="Nicolas_upshift_promotors" /id="U2712" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1360 /SigmaFactorBS="aagaaaagagagatgaagaagtgtttagtaccagaggtatac ATCCATACAAcagactctagatcATCATATACTGAATGTATGTagaaaggagacatca g" /listShort="cotR, S1317" /GFF_Attribute="listLong" /label="promotor_-10" CDS 3410240..3411202 /gene="cotR" /locus_tag="BSU_34530" /old_locus_tag="BSU34530" /function="16.13: Shape" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:11737650, 20378985" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11737650, 20378985; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="spore coat lipolytic enzyme" /protein_id="NP_391333.1" /db_xref="EnsemblGenomes-Gn:BSU34530" /db_xref="EnsemblGenomes-Tr:CAB15458" /db_xref="GOA:O06996" /db_xref="InterPro:IPR002641" /db_xref="InterPro:IPR016035" /db_xref="SubtiList:BG12423" /db_xref="UniProtKB/Swiss-Prot:O06996" /translation="MAKYRIMTFDGGGTLGALSLQLLNRLARQNPKLISRTHVFSGNS IGSFTALALASGRSPRETLQYFEDEILPAFSISRPGGPVFNQQLPYSGFIKAVRNFFP ADLQLIDLRKRIVVPSFKLYSQKLDRWTPVLFHNFPGSPYLNEKVSDVILRSSGAPAT QRAYQNYVDGYVVATNPSTASIAFAVGKANVPLDQIAVLSIGTGEAPTRLRRDTRGWG MVSADNIRPENLKNLPPNWGVLLDRSPNEPLLPFLQMIAGGNGYYESMVSANLLGDRF FRLDPRIPNFSKTDPAVVPAVIEIANKTNLQPANQFIEKNWGSK*" gene 3410240..3411202 /gene="cotR" /locus_tag="BSU_34530" /old_locus_tag="BSU34530" S_feature 3411203..3411456 /Source="Nicolas_S_feature" /locus_tag="new_3545605_3545858" /HighExp="BT, S8, S7, B36, S6, Pyr, G/S, S3, C30, S5" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigK" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S1317" downshifts complement(3411483) /Source="Nicolas_upshifts" /id="D1789" /incds=0 /nref=190 /ntot=241 /MaxReadThrough="3.19421" /MaxDrop="5.60739" /score="16.7489574" /energy="-13.2" /TU="U2713" /idTUdmin="U2713" /TUdmin="-308" /isTUend="FALSE" tRNA complement(3411487..3411562) /gene="trnQ-Arg" /locus_tag="BSU_tRNA_81" /product="tRNA-Arg" /inference="profile:tRNAscan:1.23" /note="arginine transfer RNA (CCG); Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 27749819; Product type n : RNA" /function="16.2: Construct biomass (Anabolism)" gene complement(3411487..3411562) /gene="trnQ-Arg" /locus_tag="BSU_tRNA_81" promotor_-10 complement(3411589..3411608) /Source="Nicolas_upshift_promotors" /id="U2713" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.508491508491508" /psig=1 /xcortree=2857 /SigmaFactorBS="aagatgctttgtctatttaaaaaacggcctctcgaaatagag gGTTGttatttgaaaggaatTATCGTATAATTAGTTGTGCtgacgttctcataacgca g" /listShort="trnQ-Arg" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3411610) /Source="Nicolas_upshifts" /id="U2713" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.508491508491508" /psig=1 /xcortree=2857 /SigmaFactorBS="aagatgctttgtctatttaaaaaacggcctctcgaaatagag gGTTGttatttgaaaggaatTATCGTATAATTAGTTGTGCtgacgttctcataacgca g" /listShort="trnQ-Arg" /GFF_Attribute="listLong" promotor_-35 complement(3411624..3411627) /Source="Nicolas_upshift_promotors" /id="U2713" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.508491508491508" /psig=1 /xcortree=2857 /SigmaFactorBS="aagatgctttgtctatttaaaaaacggcctctcgaaatagag gGTTGttatttgaaaggaatTATCGTATAATTAGTTGTGCtgacgttctcataacgca g" /listShort="trnQ-Arg" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 3411693..3411699 /Source="Nicolas_upshift_promotors" /id="U2714" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=726 /SigmaFactorBS="ttttaaatagacaaagcatcttaattggcaatctgacatacg atGGTTTGAacccctgtatttttGGGGAAAATGGGAAAAAGAGacgactttgcatatc a" /listShort="S1318, clpP, S1319" /GFF_Attribute="listLong" /label="promotor_-35" S_feature 3411709..3411784 /Source="Nicolas_S_feature" /locus_tag="new_3546111_3546186" /HighExp="Salt, S3, S4, Etha, S5, LoTm, Gly, M9-stat, BT, S6" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigB" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1318" upshifts 3411709 /Source="Nicolas_upshifts" /id="U2714" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=726 /SigmaFactorBS="ttttaaatagacaaagcatcttaattggcaatctgacatacg atGGTTTGAacccctgtatttttGGGGAAAATGGGAAAAAGAGacgactttgcatatc a" /listShort="S1318, clpP, S1319" /GFF_Attribute="listLong" promotor_-10 3411714..3411733 /Source="Nicolas_upshift_promotors" /id="U2714" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=726 /SigmaFactorBS="ttttaaatagacaaagcatcttaattggcaatctgacatacg atGGTTTGAacccctgtatttttGGGGAAAATGGGAAAAAGAGacgactttgcatatc a" /listShort="S1318, clpP, S1319" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 3411761..3411768 /Source="Nicolas_upshift_promotors" /id="U2715" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.975024975024975" /psig=1 /xcortree=1938 /SigmaFactorBS="aaaaagagacgactttgcatatcaggccagcttttTGTTTGA CctttattgaccaaAAATGTATCATGTAACTACAtacttacctaaaaggtgaaggagg a" /listShort="clpP" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3411782..3411801 /Source="Nicolas_upshift_promotors" /id="U2715" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.975024975024975" /psig=1 /xcortree=1938 /SigmaFactorBS="aaaaagagacgactttgcatatcaggccagcttttTGTTTGA CctttattgaccaaAAATGTATCATGTAACTACAtacttacctaaaaggtgaaggagg a" /listShort="clpP" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3411786 /Source="Nicolas_upshifts" /id="U2715" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.975024975024975" /psig=1 /xcortree=1938 /SigmaFactorBS="aaaaagagacgactttgcatatcaggccagcttttTGTTTGA CctttattgaccaaAAATGTATCATGTAACTACAtacttacctaaaaggtgaaggagg a" /listShort="clpP" /GFF_Attribute="listLong" CDS 3411832..3412425 /gene="clpP" /locus_tag="BSU_34540" /old_locus_tag="BSU34540" /EC_number="3.4.21.92" /function="16.11: Scavenge (Catabolism)" /function="16.6: Maintain" /function="16.3: Control" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:11722737, 11807061, 15317791, 16163393, 21546913, 21969594, 22226636, 27749819" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11722737, 11807061, 15317791, 16163393, 21546913, 21969594, 22226636, 27749819; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="ATP-dependent Clp protease proteolytic subunit; Maxwell's demon" /protein_id="NP_391334.1" /db_xref="EnsemblGenomes-Gn:BSU34540" /db_xref="EnsemblGenomes-Tr:CAB15459" /db_xref="GOA:P80244" /db_xref="InterPro:IPR001907" /db_xref="InterPro:IPR018215" /db_xref="InterPro:IPR023562" /db_xref="InterPro:IPR029045" /db_xref="InterPro:IPR033135" /db_xref="PDB:3KTG" /db_xref="PDB:3KTH" /db_xref="PDB:3KTI" /db_xref="PDB:3KTJ" /db_xref="PDB:3KTK" /db_xref="PDB:3TT6" /db_xref="PDB:3TT7" /db_xref="SubtiList:BG19016" /db_xref="UniProtKB/Swiss-Prot:P80244" /translation="MNLIPTVIEQTNRGERAYDIYSRLLKDRIIMLGSAIDDNVANSI VSQLLFLAAEDPEKEISLYINSPGGSITAGMAIYDTMQFIKPKVSTICIGMAASMGAF LLAAGEKGKRYALPNSEVMIHQPLGGAQGQATEIEIAAKRILLLRDKLNKVLAERTGQ PLEVIERDTDRDNFKSAEEALEYGLIDKILTHTEDKK*" gene 3411832..3412425 /gene="clpP" /locus_tag="BSU_34540" /old_locus_tag="BSU34540" downshifts 3412414 /Source="Nicolas_upshifts" /id="D1790" /incds=0 /nref=292 /ntot=300 /MaxReadThrough="4.45406" /MaxDrop="8.24306" /score="30.2626808" /energy="-14.6" /TU="U2714" /idTUdmin="U2715" /TUdmin="-5" /isTUend="TRUE" S_feature 3412459..3412857 /Source="Nicolas_S_feature" /locus_tag="new_3546861_3547259" /HighExp="Etha, dia15, Heat, LoTm, M9-stat, Gly, dia5, Diami, S8, H2O2" /AntisenseName="pgcM" /AntisenseCor="0.13310786898312499" /AntisenseRegPval="-1.5" /CDS_PredictionProba="NA" /TUshortSig="SigB" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1319" CDS complement(3412471..3413151) /gene="mdxM" /locus_tag="BSU_34550" /old_locus_tag="BSU34550" /EC_number="2.7.1.41" /EC_number="5.4.2.6" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:4275311, 11081794, 15996095" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 4275311, 11081794, 15996095; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="bifunctional beta-phosphoglucomutase / glucose-1-phosphate phosphodismutase" /protein_id="NP_391335.1" /db_xref="EnsemblGenomes-Gn:BSU34550" /db_xref="EnsemblGenomes-Tr:CAB15460" /db_xref="GOA:O06995" /db_xref="InterPro:IPR006439" /db_xref="InterPro:IPR010972" /db_xref="InterPro:IPR010976" /db_xref="InterPro:IPR023198" /db_xref="InterPro:IPR023214" /db_xref="InterPro:IPR036412" /db_xref="PDB:3NAS" /db_xref="SubtiList:BG12422" /db_xref="UniProtKB/Swiss-Prot:O06995" /translation="MKAVIFDLDGVITDTAEYHFLAWKHIAEQIDIPFDRDMNERLKG ISREESLESILIFGGAETKYTNAEKQELMHRKNRDYQMLISKLTPEDLLPGIGRLLCQ LKNENIKIGLASSSRNAPKILRRLAIIDDFHAIVDPTTLAKGKPDPDIFLTAAAMLDV SPADCAAIEDAEAGISAIKSAGMFAVGVGQGQPMLGADLVVRQTSDLTLELLHEEWEQ YRIRESIP*" gene complement(3412471..3413151) /gene="mdxM" /locus_tag="BSU_34550" /old_locus_tag="BSU34550" downshifts complement(3412495) /Source="Nicolas_upshifts" /id="D1791" /incds=0 /nref=2 /ntot=36 /MaxReadThrough="3.4944" /MaxDrop="3.50516" /score="-9.43329271" /energy="-14.6" /TU="U2718" /idTUdmin="U2718" /TUdmin="-506" /isTUend="FALSE" CDS complement(3413148..3414833) /gene="mdxL" /locus_tag="BSU_34560" /old_locus_tag="BSU34560" /EC_number="3.2.1.10" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:9573215, 10229946, 1670768" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9573215, 10229946, 1670768; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="oligo-1,4-1,6-alpha-glucosidase (sucrase-maltase-isomaltase)" /protein_id="NP_391336.1" /db_xref="EnsemblGenomes-Gn:BSU34560" /db_xref="EnsemblGenomes-Tr:CAB15461" /db_xref="GOA:O06994" /db_xref="InterPro:IPR006047" /db_xref="InterPro:IPR017853" /db_xref="InterPro:IPR032091" /db_xref="PDB:4M56" /db_xref="PDB:4M8U" /db_xref="PDB:4MAZ" /db_xref="PDB:4MB1" /db_xref="SubtiList:BG12421" /db_xref="UniProtKB/Swiss-Prot:O06994" /translation="MSEWWKEAVVYQIYPRSFYDANGDGFGDLQGVIQKLDYIKNLGA DVIWLSPVFDSPQDDNGYDISDYKNMYEKFGTNEDMFQLIDEVHKRGMKIVMDLVVNH TSDEHAWFAESRKSKDNPYRDYYLWKDPKPDGSEPNNWGSIFSGSAWTYDEGTGQYYL HYFSKKQPDLNWENEAVRREVYDVMRFWMDRGVDGWRMDVIGSISKYTDFPDYETDHS RSYIVGRYHSNGPRLHEFIQEMNREVLSHYDCMTVGEANGSDIEEAKKYTDASRQELN MIFTFEHMDIDKEQNSPNGKWQIKPFDLIALKKTMTRWQTGLMNVGWNTLYFENHDQP RVISRWGNDRKLRKECAKAFATVLHGMKGTPFIYQGEEIGMVNSDMPLEMYDDLEIKN AYRELVVENKTMSEKEFVKAVMIKGRDHARTPMQWDAGKHAGFTAGDPWIPVNSRYQD INVKESLEDQDSIFFYYQKLIQLRKQYKIMIYGDYQLLQENDPQVFSYLREYRGEKLL VVVNLSEEKALFEAPPELIHERWKVLISNYPQERADLKSISLKPYEAVMGISI*" gene complement(3413148..3414833) /gene="mdxL" /locus_tag="BSU_34560" /old_locus_tag="BSU34560" CDS complement(3414826..3417099) /gene="mdxK" /locus_tag="BSU_34570" /old_locus_tag="BSU34570" /EC_number="2.4.1.8" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:16707683, 28527120" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16707683, 28527120; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="maltose phosphorylase" /protein_id="NP_391337.1" /db_xref="EnsemblGenomes-Gn:BSU34570" /db_xref="EnsemblGenomes-Tr:CAB15462" /db_xref="GOA:O06993" /db_xref="InterPro:IPR005194" /db_xref="InterPro:IPR005195" /db_xref="InterPro:IPR005196" /db_xref="InterPro:IPR008928" /db_xref="InterPro:IPR011013" /db_xref="InterPro:IPR017045" /db_xref="SubtiList:BG12420" /db_xref="UniProtKB/Swiss-Prot:O06993" /translation="MINQRLFEIDEWKIKTNTFNKEHTRLLESLTSLANGYMGVRGNF EEGYSGDSHQGTYIAGVWFPDKTRVGWWKNGYPEYFGKVINAMNFMGIGLYVDGEKID LHQNPIELFEVELNMKEGILRRSAVVRIQDKTVRIRSERFLSLAVKELCAIHYEAECL TGDAVITLVPYLDGNVANEDSNYQEQFWQEEAKGADSHSGHLAAKTIENPFGTPRFTV LAAMANETEGFVHESFKTTEMYVENRYSYQTKASLKKFVIVTTSRDFREEELLSKAKE LLADVVENGYEDAKRRHTDRWKERWAKADIEIKGDEELQQGIRYNIFQLFSTYYGGDA RLNIGPKGFTGEKYGGAAYWDTEAYAVPMYLATAEPEVTKNLLLYRYHQLEAAKRNAA KLGMKGALYPMVTFTGDECHNEWEITFEEIHRNGAICYAIYNYINYTGDRNYMEEYGI DVLVAVSRFWADRVHFSKRKNKYMIHGVTGPNEYENNVNNNWYTNVIAAWTLEYTLQS LESISAEKRRHLDVQEVELEVWREIIQHMYYPFSEELQIFVQHDTFLDKDLQTVDELD PAERPLYQNWSWDKILRSNFIKQADVLQGIYLFNDRFTMEEKRRNFEFYEPMTVHESS LSPSVHAILAAELKLEKKALELYKRTARLDLDNYNHDTEEGLHITSMTGSWLAIVHGF AGMRTANETLSFAPFLPKEWDEYSFNINYRNRLINVTVDEKRVIFELVKGEPLHMNVY EEPVVLQGRCERRTPNE*" gene complement(3414826..3417099) /gene="mdxK" /locus_tag="BSU_34570" /old_locus_tag="BSU34570" CDS complement(3417077..3417961) /gene="mdxJ" /locus_tag="BSU_34580" /old_locus_tag="BSU34580" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16707683, 16850406, 20436965; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative component of maltodextrin transporter" /protein_id="NP_391338.1" /db_xref="EnsemblGenomes-Gn:BSU34580" /db_xref="EnsemblGenomes-Tr:CAB15463" /db_xref="GOA:O06992" /db_xref="InterPro:IPR009574" /db_xref="SubtiList:BG12419" /db_xref="UniProtKB/Swiss-Prot:O06992" /translation="MKNLENKSFIIRCLKAAASPSGVCRYGNTFSWLQLSFLFLFLTA CLMAPLAVSFVKMDRFSVSSFMPSAIQGVNDQFADQLQGFQIRNGKLTGGKSSERIED GQNVMAVDMKHEYETSGENGRLKVTGFENAIIFQPDQLVITDQNETGFSVGYAKMDVK LEKPNVHDVEVLIDTLWLAQYKPMIMMLAYTVVSMIQLLLTFVLAGGLWITKISNMVS IASFKEAASIAICASALPAFAAAAIGMVHFDLITVLMIHSCGVTLMISFAFRYLTKTR RDNGNLHSGGNDDKSAVI*" gene complement(3417077..3417961) /gene="mdxJ" /locus_tag="BSU_34580" /old_locus_tag="BSU34580" CDS complement(3417967..3418803) /gene="mdxG" /locus_tag="BSU_34590" /old_locus_tag="BSU34590" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:15849754, 16707683, 16850406" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15849754, 16707683, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="maltodextrin ABC transporter (permease)" /protein_id="NP_391339.1" /db_xref="EnsemblGenomes-Gn:BSU34590" /db_xref="EnsemblGenomes-Tr:CAB15464" /db_xref="GOA:O06991" /db_xref="InterPro:IPR000515" /db_xref="InterPro:IPR035906" /db_xref="SubtiList:BG12418" /db_xref="UniProtKB/Swiss-Prot:O06991" /translation="MNASTARMLNKICTYLFLTLLSIVIIYPLLITASSAFRVGNSAA FQLDFSGSWTLDHFKRLFDETLYLNWYSNTLVIALSVMVLQVTIVTLAGYSYSRYRFA GRKKSLIFFLIIQMVPTMAALTAFYVLAMLIGALDQYWFLTAIYIGGGIPMNTWLMKG YFDTVPREIDEAARIDGAGHLRIFASIVLPLVKPMLAVQALWAFMAPFGDYLLTKFLL RSPERLTIAVGLQSFISNPQQQKVALFAAGAILAALPICVLFFFLQKNFVSGLTAGGT KG*" gene complement(3417967..3418803) /gene="mdxG" /locus_tag="BSU_34590" /old_locus_tag="BSU34590" CDS complement(3418804..3420111) /gene="mdxF" /locus_tag="BSU_34600" /old_locus_tag="BSU34600" /experiment="publication(s) with functional evidences, PMID:15849754, 16707683, 16850406" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15849754, 16707683, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="maltodextrin ABC transport system (permease)" /protein_id="NP_391340.1" /db_xref="EnsemblGenomes-Gn:BSU34600" /db_xref="EnsemblGenomes-Tr:CAB15465" /db_xref="GOA:O06990" /db_xref="InterPro:IPR000515" /db_xref="InterPro:IPR035277" /db_xref="InterPro:IPR035906" /db_xref="SubtiList:BG12417" /db_xref="UniProtKB/Swiss-Prot:O06990" /translation="MNKHHTLTKQKRKAGLLSIIPGLGQIANQQLSKGLLFLAITGLF AFELCVFGIQALTGLMTLGSVPGEDHSLFMLIEGTLQLIVTMIFLMFYIFNIHDSRKT AAMKAAGLEVNTTAKDMICHAGDKGFPYLFTLPAYIMMVFVIIFPVLVTLFVALTNYD FYHIPPNRLIDWVGFKNFLNIFFLGSYRETFVNVLGWTVIWTICATTLQIILGIVTAL FVNQDFIKGKRIFRMIFLFPWAVPAFITIMSFSNMFNDSIGAVNAQVIPLFNHLPFVE LPAIAWKTDPFWTKTALIMIQTWLGFPYIYVMVTGVLQAIPGELYEAAKIDGATFIQR FRHITFPMILFATAPVMITQYTFNFNNFSIIYLFNEGGPGSAGAGAGSTDILISWIYK LTTGTSPQYSVAAAVTLLISFIVIGISLIAFKKSNAFGNEEVM*" gene complement(3418804..3420111) /gene="mdxF" /locus_tag="BSU_34600" /old_locus_tag="BSU34600" promotor_-35 3419169..3419178 /Source="Nicolas_upshift_promotors" /id="U2716" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.994005994005994" /psig="0.994005994005994" /xcortree=1371 /SigmaFactorBS="atctttgccgcttcatacaattcacctggaatcgCCTGAAGC ACtcccgttaccatGACATATATATATGGAAAGCcgagccacgtttgaatcataatga g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3419191..3419210 /Source="Nicolas_upshift_promotors" /id="U2716" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.994005994005994" /psig="0.994005994005994" /xcortree=1371 /SigmaFactorBS="atctttgccgcttcatacaattcacctggaatcgCCTGAAGC ACtcccgttaccatGACATATATATATGGAAAGCcgagccacgtttgaatcataatga g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3419195 /Source="Nicolas_upshifts" /id="U2716" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.994005994005994" /psig="0.994005994005994" /xcortree=1371 /SigmaFactorBS="atctttgccgcttcatacaattcacctggaatcgCCTGAAGC ACtcccgttaccatGACATATATATATGGAAAGCcgagccacgtttgaatcataatga g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" CDS complement(3420151..3421404) /gene="mdxE" /locus_tag="BSU_34610" /old_locus_tag="BSU34610" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:16707683" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16707683; Product type lp: lipoprotein" /codon_start=1 /transl_table=11 /product="maltose/maltodextrin-binding lipoprotein" /protein_id="NP_391341.1" /db_xref="EnsemblGenomes-Gn:BSU34610" /db_xref="EnsemblGenomes-Tr:CAB15466" /db_xref="GOA:O06989" /db_xref="InterPro:IPR006060" /db_xref="SubtiList:BG12416" /db_xref="UniProtKB/Swiss-Prot:O06989" /translation="MVLLKKGFAILAASFLAIGLAACSSSKNPASSDGKKVLTVSVEE TYKEYIESIKTKFEKENDVTVKIVEKQMFEQLEALPLDGPAGNAPDVMLAAYDRIGGL GQQGHLLDIKPSNTKSFGDKEMQQVTVDGKVYGMPLVIETLILYYNKDLLKTAPKTFK DLEKLTEDPRFAFASEKGKSTGFLAKWTDFYMSYGLLAGYGGYVFGKNGTDSGDIGLN NKGAVEAVKYAEKWFETYWPKGMQDNSSADDFIQQMFLEGKAAAIIGGPWSAANYKEA KLNYGAAPIPTLPNGEEYAPFAGGKGWVASKYTKEPELAEKWLEYAANDANAYAFYED TNEVPANTAARKKADEQKNELTSAVIKQYETATPTPNIPEMAEVWTGAESLIFDAASG KKSTQTSANDAVNVIKENIKEKYVK*" gene complement(3420151..3421404) /gene="mdxE" /locus_tag="BSU_34610" /old_locus_tag="BSU34610" S_feature complement(3421405..3421499) /Source="Nicolas_S_feature" /locus_tag="new_3555807_3555901_c" /HighExp="T1.0H, T0.30H, BC, T1.30H, M40t90, M0t90, BI, B60, S8, M9-stat" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.804" /TUlongSig="NA" /TUlongPSig="NA" /label="S1320" CDS complement(3421500..3423269) /gene="mdxD" /locus_tag="BSU_34620" /old_locus_tag="BSU34620" /EC_number="3.2.1.-" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:10825545, 15650689, 16707683, 19465663, 27871383, 27871383" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10825545, 15650689, 16707683, 19465663, 27871383, 27871383; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="maltogenic alpha-amylase" /protein_id="NP_391342.1" /db_xref="EnsemblGenomes-Gn:BSU34620" /db_xref="EnsemblGenomes-Tr:CAB15467" /db_xref="GOA:O06988" /db_xref="InterPro:IPR004185" /db_xref="InterPro:IPR006047" /db_xref="InterPro:IPR013777" /db_xref="InterPro:IPR013783" /db_xref="InterPro:IPR017853" /db_xref="SubtiList:BG12415" /db_xref="UniProtKB/Swiss-Prot:O06988" /translation="MMEYAAIHHQPFSTDAYSYDGRTVHIKIRTKKGDADHIRFIWGD PYEYNDGKWSANEQPMRKIAATEMHDYWFAEVVPPFRRLQYAFVVTDDHEDIFFGSSG VCPYNEKTLETIHYYFKFPFVHEADTFQAPEWVKSTVWYQIFPERFANGREDLSPKNA LPWGSKDPDVNDFFGGDLQGIVDKLDYLEDLGVNGIYLTPIFSAPSNHKYDTLDYFSI DPHFGDPELFRTLVSQLHQRGMRIMLDAVFNHIGSASPQWQDVVKNGDQSRYKDWFHI HSFPVTDDNYDRFAFTADMPKLNTANPEVQKYLLDIALYWIREFDIDGWRLDVANEVD HVFWKTFRQAVSTEKPDVYILGEIWHSAEPWLRGDEFHAAMNYPFTEPMIEYFADQTI SASRMAHRVNAHLMNGMKQANEVMFNLLDSHDTKRLLTRCRNDEKKARALLAFMFAQT GSPCIYYGTEIGLNGENDPLCRKCMVWEKEKQNQDMLQFMKRLIALRKQENTLLTEGH LEWNLLDDKNDFISFSRTLDEKILIYFFNQGNVVQHVSLRELNIDRNKKICDAWTEQP LQHHDVIAVQPGEFLILSAAAPV*" gene complement(3421500..3423269) /gene="mdxD" /locus_tag="BSU_34620" /old_locus_tag="BSU34620" promotor_-35 3423190..3423195 /Source="Nicolas_upshift_promotors" /id="U2717" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.957042957042957" /psig="0.957042957042957" /xcortree=1040 /SigmaFactorBS="gatctgcatcaccttttttcgtccgaatcTTGATAtgcacag tccgcccaTCATAAGAATAAGCATCTGtgctgaatggctggtgatgaatcgctgcata t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3423211..3423229 /Source="Nicolas_upshift_promotors" /id="U2717" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.957042957042957" /psig="0.957042957042957" /xcortree=1040 /SigmaFactorBS="gatctgcatcaccttttttcgtccgaatcTTGATAtgcacag tccgcccaTCATAAGAATAAGCATCTGtgctgaatggctggtgatgaatcgctgcata t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3423221 /Source="Nicolas_upshifts" /id="U2717" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.957042957042957" /psig="0.957042957042957" /xcortree=1040 /SigmaFactorBS="gatctgcatcaccttttttcgtccgaatcTTGATAtgcacag tccgcccaTCATAAGAATAAGCATCTGtgctgaatggctggtgatgaatcgctgcata t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 complement(3423307..3423326) /Source="Nicolas_upshift_promotors" /id="U2718" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.538461538461538" /psig="0.804195804195804" /xcortree=343 /SigmaFactorBS="cgccttattctgttatcggtaacagggtgaaaagGATTGTTC ccacaatttcatCATGATACTTTCAAACTATGagccggcttcaataaaacggaaatca a" /listShort="mdxD, S1320, mdxE, mdxF, mdxG, yvdJ, malK, malL, pgcM" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3423320) /Source="Nicolas_upshifts" /id="U2718" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.538461538461538" /psig="0.804195804195804" /xcortree=343 /SigmaFactorBS="cgccttattctgttatcggtaacagggtgaaaagGATTGTTC ccacaatttcatCATGATACTTTCAAACTATGagccggcttcaataaaacggaaatca a" /listShort="mdxD, S1320, mdxE, mdxF, mdxG, yvdJ, malK, malL, pgcM" /GFF_Attribute="listLong" promotor_-35 complement(3423339..3423346) /Source="Nicolas_upshift_promotors" /id="U2718" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.538461538461538" /psig="0.804195804195804" /xcortree=343 /SigmaFactorBS="cgccttattctgttatcggtaacagggtgaaaagGATTGTTC ccacaatttcatCATGATACTTTCAAACTATGagccggcttcaataaaacggaaatca a" /listShort="mdxD, S1320, mdxE, mdxF, mdxG, yvdJ, malK, malL, pgcM" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3423382..3424332) /gene="mdxR" /locus_tag="BSU_34630" /old_locus_tag="BSU34630" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:16707683, 23951303" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16707683, 23951303; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional activator of the maltodextrin operon (LacI family)" /protein_id="NP_391343.1" /db_xref="EnsemblGenomes-Gn:BSU34630" /db_xref="EnsemblGenomes-Tr:CAB15468" /db_xref="GOA:O06987" /db_xref="InterPro:IPR000843" /db_xref="InterPro:IPR010982" /db_xref="InterPro:IPR028082" /db_xref="SubtiList:BG12414" /db_xref="UniProtKB/Swiss-Prot:O06987" /translation="MATLSDVAKKANVSKMTVSRVINHPETVTDELKKLVHSAMKELN YIPNYAARALVQNRTQVVKLLILEEMDTTEPYYMNLLTGISRELDRNHYALQLVTRNS LNIGQCDGIIATGLRKNDFEGVIKAFEKPLVVFGQNEMGYDFIDVNNEKGTFMATRHV MGLGEREVVFFGIDLDEPFERAREQGYIRAMNKSFKKSNMFRIDNSSKKSECLARELL KSMDNQAAFVCASDRIALGVIRAAQSLGKRIPEDVAVTGNDGVFLDRISSPRLTTVRQ PVVEMGEACAKMLLKKMNEDGAAQGSLFFEPELIVRESTL*" gene complement(3423382..3424332) /gene="mdxR" /locus_tag="BSU_34630" /old_locus_tag="BSU34630" promotor_-10 complement(3424347..3424365) /Source="Nicolas_upshift_promotors" /id="U2719" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.98101898101898" /psig="0.98101898101898" /xcortree=516 /SigmaFactorBS="ttctctttggcctgcatcgtatatttagcagtaatAGAGGAC TTtatcactagttTGGATAATAAGCACAGATAaggaggggatgaaaatggcaacattg t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3424360) /Source="Nicolas_upshifts" /id="U2719" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.98101898101898" /psig="0.98101898101898" /xcortree=516 /SigmaFactorBS="ttctctttggcctgcatcgtatatttagcagtaatAGAGGAC TTtatcactagttTGGATAATAAGCACAGATAaggaggggatgaaaatggcaacattg t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(3424377..3424385) /Source="Nicolas_upshift_promotors" /id="U2719" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.98101898101898" /psig="0.98101898101898" /xcortree=516 /SigmaFactorBS="ttctctttggcctgcatcgtatatttagcagtaatAGAGGAC TTtatcactagttTGGATAATAAGCACAGATAaggaggggatgaaaatggcaacattg t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" downshifts complement(3424466) /Source="Nicolas_upshifts" /id="D1792" /incds=0 /nref=134 /ntot=243 /MaxReadThrough="0.22626" /MaxDrop="5.17193" /score="21.4455132" /energy="-10" /TU="NA" /idTUdmin="U2720" /TUdmin="-3" /isTUend="TRUE" CDS complement(3424538..3425113) /gene="yvdD" /locus_tag="BSU_34640" /old_locus_tag="BSU34640" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative enzyme" /protein_id="NP_391344.1" /db_xref="EnsemblGenomes-Gn:BSU34640" /db_xref="EnsemblGenomes-Tr:CAB15469" /db_xref="InterPro:IPR005269" /db_xref="InterPro:IPR031100" /db_xref="PDB:1T35" /db_xref="SubtiList:BG12413" /db_xref="UniProtKB/Swiss-Prot:O06986" /translation="MKTICVFAGSNPGGNEAYKRKAAELGVYMAEQGIGLVYGGSRVG LMGTIADAIMENGGTAIGVMPSGLFSGEVVHQNLTELIEVNGMHERKAKMSELADGFI SMPGGFGTYEELFEVLCWAQIGIHQKPIGLYNVNGYFEPMMKMVKYSIQEGFSNESHL KLIHSSSRPDELIEQMQNYSYPILEKKWTEI*" gene complement(3424538..3425113) /gene="yvdD" /locus_tag="BSU_34640" /old_locus_tag="BSU34640" downshifts complement(3424550) /Source="Nicolas_upshifts" /id="D1793" /incds=0 /nref=30 /ntot=209 /MaxReadThrough="4.23893" /MaxDrop="3.6086" /score="21.4455132" /energy="-10" /TU="U2720" /idTUdmin="U2720" /TUdmin="-87" /isTUend="FALSE" promotor_-10 complement(3425156..3425175) /Source="Nicolas_upshift_promotors" /id="U2720" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.61038961038961" /psig="0.998001998001998" /xcortree=3064 /SigmaFactorBS="caacctcatcactcctgcattctttatgtatttcaTATTGAT AttatcacatgaagaTGGGACAATATATAGTGTGTttttgaatgtttaacacgatata t" /listShort="yvdD" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 3425162..3425169 /Source="Nicolas_upshift_promotors" /id="U2721" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.856143856143856" /psig="0.998001998001998" /xcortree=3065 /SigmaFactorBS="catctccgcatctatatatcgtgttaaacattcaaaaacaca cTATATATTgtcccatcttcaTGTGATAATATCAATATGAAatacataaagaatgcag g" /listShort="yvdC" /GFF_Attribute="listLong" /label="promotor_-35" upshifts complement(3425172) /Source="Nicolas_upshifts" /id="U2720" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.61038961038961" /psig="0.998001998001998" /xcortree=3064 /SigmaFactorBS="caacctcatcactcctgcattctttatgtatttcaTATTGAT AttatcacatgaagaTGGGACAATATATAGTGTGTttttgaatgtttaacacgatata t" /listShort="yvdD" /GFF_Attribute="listLong" upshifts 3425179 /Source="Nicolas_upshifts" /id="U2721" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.856143856143856" /psig="0.998001998001998" /xcortree=3065 /SigmaFactorBS="catctccgcatctatatatcgtgttaaacattcaaaaacaca cTATATATTgtcccatcttcaTGTGATAATATCAATATGAAatacataaagaatgcag g" /listShort="yvdC" /GFF_Attribute="listLong" promotor_-10 3425182..3425201 /Source="Nicolas_upshift_promotors" /id="U2721" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.856143856143856" /psig="0.998001998001998" /xcortree=3065 /SigmaFactorBS="catctccgcatctatatatcgtgttaaacattcaaaaacaca cTATATATTgtcccatcttcaTGTGATAATATCAATATGAAatacataaagaatgcag g" /listShort="yvdC" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 complement(3425190..3425197) /Source="Nicolas_upshift_promotors" /id="U2720" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.61038961038961" /psig="0.998001998001998" /xcortree=3064 /SigmaFactorBS="caacctcatcactcctgcattctttatgtatttcaTATTGAT AttatcacatgaagaTGGGACAATATATAGTGTGTttttgaatgtttaacacgatata t" /listShort="yvdD" /GFF_Attribute="listLong" /label="promotor_-35" CDS 3425230..3425550 /gene="yvdC" /locus_tag="BSU_34650" /old_locus_tag="BSU34650" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 16120674, 19684115; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative pyrophosphohydrolase" /protein_id="NP_391345.1" /db_xref="EnsemblGenomes-Gn:BSU34650" /db_xref="EnsemblGenomes-Tr:CAB15470" /db_xref="InterPro:IPR004518" /db_xref="InterPro:IPR011411" /db_xref="SubtiList:BG12412" /db_xref="UniProtKB/Swiss-Prot:O32263" /translation="MQLADAEKWMKEFYEKRGWTEYGPFIRVGFLMEEAGELARAVRA YEIGRDRPDEKESSRAEQKQELIEEMGDVIGNIAILADMYGVSLEDVMKAHQEKLTKR FEHA*" gene 3425230..3425550 /gene="yvdC" /locus_tag="BSU_34650" /old_locus_tag="BSU34650" downshifts 3425531 /Source="Nicolas_upshifts" /id="D1794" /incds=0 /nref=134 /ntot=247 /MaxReadThrough="2.19085" /MaxDrop="5.46819" /score="35.8658106" /energy="-11.6" /TU="NA" /idTUdmin="U2721" /TUdmin=0 /isTUend="TRUE" downshifts complement(3425577) /Source="Nicolas_upshifts" /id="D1795" /incds=0 /nref=13 /ntot=56 /MaxReadThrough="0.462300000000001" /MaxDrop="6.90114" /score="30.4681035" /energy="-11.3" /TU="NA" /idTUdmin="U2722" /TUdmin=8 /isTUend="TRUE" CDS complement(3425577..3427169) /gene="yvdB" /locus_tag="BSU_34660" /old_locus_tag="BSU34660" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative anion transporter" /protein_id="NP_391346.1" /db_xref="EnsemblGenomes-Gn:BSU34660" /db_xref="EnsemblGenomes-Tr:CAB15471" /db_xref="GOA:O06984" /db_xref="InterPro:IPR001902" /db_xref="InterPro:IPR002645" /db_xref="InterPro:IPR011547" /db_xref="InterPro:IPR036513" /db_xref="SubtiList:BG12411" /db_xref="UniProtKB/Swiss-Prot:O06984" /translation="MRFSGRFKGYNLQKFQKDLIAGIVVGVVAIPLGMAFAIASGVEP EYGLYTVVIAGICISLFGGSKYQIGGPTGAFVPILFGIIMQYGLENLLIAGFMAGVML VLFGLFKLGKIMKFVPKPVIVGFTAGIAVLIFTEQIANFLGLRNVEKHENFHHNMFEI VQQLGTFNVYAILTAVIGLVILLVSAKVMPKVPGALLALLISTVVAVVFFPDRMATIG STYGEIPRHLPEFQFPELTLDKMVMLFPAALVIALLGGLESILSAMVADNMKGSKHDS NKELVGQGIANMAAPLFGGIPATGAIARTATNIKNGAVSPVSGVVHGVVVLLVLLVFA PYASHVPLASMAPILMVVAWNMSERKEVANMLRLKNADSFILAATFALTVLFDLIIGV ATGLLLAFVFFIRRMSEATRIHNQETHPVLAKREDPSVSMYAIEGPLFFGSIDSLESS LLEHVQKKPKTLILLMNKVHYMDTSAEAVLGNIMNRIKRHNGKLMIVGLQSQPKELLH KTGLFHKIGKQHFFDHHDEITG*" gene complement(3425577..3427169) /gene="yvdB" /locus_tag="BSU_34660" /old_locus_tag="BSU34660" CDS complement(3427188..3427781) /gene="yvdA" /locus_tag="BSU_34670" /old_locus_tag="BSU34670" /EC_number="4.2.1.1" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 10611359; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative carbonic anhydrase" /protein_id="NP_391347.1" /db_xref="EnsemblGenomes-Gn:BSU34670" /db_xref="EnsemblGenomes-Tr:CAB15472" /db_xref="GOA:O06983" /db_xref="InterPro:IPR001765" /db_xref="InterPro:IPR036874" /db_xref="SubtiList:BG12410" /db_xref="UniProtKB/Swiss-Prot:O06983" /translation="MNQMVSLTSILEHNQRFVSEKKYEPYKTTKFPSKKLVIVTCMDT RLTELLPQAMGLKNGDAKIVKNAGAIVSHPFGSVMRSILVAIYELQAEEVCIVGHHEC GMSGLNASSILEKAKERGVEDSCLNLLTSAGLDLKTWLTGFHSVEESVSHSVNMIKNH PLLPKKVPVHGLVIHPETGKLDVVINGYETELINNHS*" gene complement(3427188..3427781) /gene="yvdA" /locus_tag="BSU_34670" /old_locus_tag="BSU34670" promotor_-10 complement(3427823..3427842) /Source="Nicolas_upshift_promotors" /id="U2722" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.38961038961039" /psig="0.98901098901099" /xcortree=371 /SigmaFactorBS="ttctacagtccaattatagtgtctttttttgaaaaCCTTTtc ttggcttattccTATGCTATAATTCCTTACTGtaagctgggtaagaaggcttgcaaaa t" /listShort="yvdA, yvdB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3427836) /Source="Nicolas_upshifts" /id="U2722" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.38961038961039" /psig="0.98901098901099" /xcortree=371 /SigmaFactorBS="ttctacagtccaattatagtgtctttttttgaaaaCCTTTtc ttggcttattccTATGCTATAATTCCTTACTGtaagctgggtaagaaggcttgcaaaa t" /listShort="yvdA, yvdB" /GFF_Attribute="listLong" promotor_-35 complement(3427857..3427861) /Source="Nicolas_upshift_promotors" /id="U2722" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.38961038961039" /psig="0.98901098901099" /xcortree=371 /SigmaFactorBS="ttctacagtccaattatagtgtctttttttgaaaaCCTTTtc ttggcttattccTATGCTATAATTCCTTACTGtaagctgggtaagaaggcttgcaaaa t" /listShort="yvdA, yvdB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 3427907..3427912 /Source="Nicolas_upshift_promotors" /id="U2723" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.934065934065934" /psig="0.934065934065934" /xcortree=962 /SigmaFactorBS="aaaaagacactataattggactgtagaatcaaaacataAACA TTtatatctttcaaagaTAATAAAATTTATATTTAAtgcatcctataatccggctgca g" /listShort="yvcT" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3427928..3427946 /Source="Nicolas_upshift_promotors" /id="U2723" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.934065934065934" /psig="0.934065934065934" /xcortree=962 /SigmaFactorBS="aaaaagacactataattggactgtagaatcaaaacataAACA TTtatatctttcaaagaTAATAAAATTTATATTTAAtgcatcctataatccggctgca g" /listShort="yvcT" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3427929 /Source="Nicolas_upshifts" /id="U2723" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.934065934065934" /psig="0.934065934065934" /xcortree=962 /SigmaFactorBS="aaaaagacactataattggactgtagaatcaaaacataAACA TTtatatctttcaaagaTAATAAAATTTATATTTAAtgcatcctataatccggctgca g" /listShort="yvcT" /GFF_Attribute="listLong" promotor_-35 3428102..3428109 /Source="Nicolas_upshift_promotors" /id="U2724" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.74025974025974" /psig=1 /xcortree=1931 /SigmaFactorBS="gttcaaaagaaccagaaattaaaaaaacgcagctaTATTTTT AacatctatttattTTCGATATAATGAATTAGACaacagccataaagggggagccttg t" /listShort="yvcT" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3428123..3428142 /Source="Nicolas_upshift_promotors" /id="U2724" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.74025974025974" /psig=1 /xcortree=1931 /SigmaFactorBS="gttcaaaagaaccagaaattaaaaaaacgcagctaTATTTTT AacatctatttattTTCGATATAATGAATTAGACaacagccataaagggggagccttg t" /listShort="yvcT" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3428127 /Source="Nicolas_upshifts" /id="U2724" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.74025974025974" /psig=1 /xcortree=1931 /SigmaFactorBS="gttcaaaagaaccagaaattaaaaaaacgcagctaTATTTTT AacatctatttattTTCGATATAATGAATTAGACaacagccataaagggggagccttg t" /listShort="yvcT" /GFF_Attribute="listLong" CDS 3428164..3429141 /gene="yvcT" /locus_tag="BSU_34680" /old_locus_tag="BSU34680" /EC_number="1.1.1.215" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 9811658, 25769838; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative 2-ketogluconate reductase; hydroxypyruvate / glyoxylate reductase" /protein_id="NP_391348.1" /db_xref="EnsemblGenomes-Gn:BSU34680" /db_xref="EnsemblGenomes-Tr:CAB15473" /db_xref="GOA:O32264" /db_xref="InterPro:IPR006139" /db_xref="InterPro:IPR006140" /db_xref="InterPro:IPR029752" /db_xref="InterPro:IPR029753" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG12409" /db_xref="UniProtKB/Swiss-Prot:O32264" /translation="MLKPFVFITKPIPEEIEAFIGEHCRYEVWQEDTLPSDVLFEKLK EAEGLLTSGTSGPSINRELLEHAPKLKVVSNQSVGYDNFDIEAMKERGVVGTHTPYTL DDTVADLAFSLILSSARRVAELDRFVRAGKWGTVEEEALFGIDVHHQTLGIIGMGRIG EQAARRAKFGFDMEVLYHNRHRKQETEDSIGVKYAELDTLLEQSDFILLITPLTDETY HMIGEREFKLMKNSAIFVNISRGKTVDEKALIRALQEGWIRGAGLDVYEKEPVTQDNP LLQLDNVTLLPHIGSATAKVRFNMCKQAAENMLAAIQGQTPKNLTREFQ*" gene 3428164..3429141 /gene="yvcT" /locus_tag="BSU_34680" /old_locus_tag="BSU34680" downshifts 3429113 /Source="Nicolas_upshifts" /id="D1796" /incds=0 /nref=223 /ntot=269 /MaxReadThrough="2.44036" /MaxDrop="5.93476" /score="1.05732532" /energy="-14.7" /TU="NA" /idTUdmin="U2724" /TUdmin="-4" /isTUend="TRUE" CDS complement(3429179..3431119) /gene="psdB" /locus_tag="BSU_34690" /old_locus_tag="BSU34690" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:15849754, 16850406, 21078927, 27997719" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15849754, 16850406, 21078927, 27997719; Product type t: transporter" /codon_start=1 /transl_table=11 /product="lantibiotic ABC transporter (permease)" /protein_id="NP_391349.1" /db_xref="EnsemblGenomes-Gn:BSU34690" /db_xref="EnsemblGenomes-Tr:CAB15474" /db_xref="GOA:O06981" /db_xref="InterPro:IPR003838" /db_xref="InterPro:IPR027022" /db_xref="SubtiList:BG12408" /db_xref="UniProtKB/Swiss-Prot:O06981" /translation="MNLRTIARKNILGNLQRYVAYFLSCVFAVSVFFVFTSFIFHPDV NEDNIYGGSLVKTCLSAALVVIIVFCIFFITYSNSAFLQARKKEFGLLTLFGTSKQQL RKMIYYEQSLISLAAIAAGIGAGLLFSKLFFMIMTWMLSVKVPISFAIVPKAFVMTIA GFLILFQTLLILSLGRIRKLEIIELIKSAKKPKSLPVYSKWLTVLSLLCLGSGYYLSA TANAIDMMFRVFPILILVLIGTYFFFTQSSVAFFRMLYRKKHSFYKGTNIIVRSNMIF RLKDHARMLFLTSVITAVILTATGVIYMFYSDLQRQEEQSIPQSVSWVEKDASRFQVM KPETAENTLKKAHAVITYKVDATGIPVTFQSDLPYGNKKMEAEALLISEKVYNQVAKE KGFPVIHLQENEAFINVSFQMMVKDTFGEGETAAFHMKSGKTLSYVMKKQQNKGILMS VDGVSRLLVVSEKSFDSLSQDVPLKEQMRMVGYELEHWQETVDVSEKLENMVPKEHTS DFQTRAPSYQIVKQGVALMLFIGLFVSVLFFIVQGSMLYLRMFTEIEDTGVQVLALKR IGVTDKEIHSILGKQIGFLFFIPFIAGTIHAGFAYAALSNMLNSNLFLEAVIVIFIYF VFQALYYIVTRHIYKRAVLQRM*" gene complement(3429179..3431119) /gene="psdB" /locus_tag="BSU_34690" /old_locus_tag="BSU34690" downshifts complement(3429203) /Source="Nicolas_upshifts" /id="D1797" /incds=0 /nref=11 /ntot=187 /MaxReadThrough="0.26118" /MaxDrop="4.59213" /score="26.9028733" /energy="-14.7" /TU="NA" /idTUdmin="U2725" /TUdmin=34 /isTUend="FALSE" CDS complement(3431094..3431873) /gene="psdA" /locus_tag="BSU_34700" /old_locus_tag="BSU34700" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:12432961, 14651641, 21078927, 27997719" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12432961, 14651641, 21078927, 27997719; Product type t: transporter" /codon_start=1 /transl_table=11 /product="lantibiotic ABC transporter (ATP-binding protein)" /protein_id="NP_391350.1" /db_xref="EnsemblGenomes-Gn:BSU34700" /db_xref="EnsemblGenomes-Tr:CAB15475" /db_xref="GOA:O06980" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG12407" /db_xref="UniProtKB/Swiss-Prot:O06980" /translation="MNVLQTTNLSKTYYSNKGTISYQALSAFDLSVSKGEFVGIMGPS GSGKTTLLNLLATIDKPTQGEMMINGIQPKTLKDQELALFRRRELGFVFQDFNLLDTL TIRENILLPLALDKVKLREMEARLDELADTLQIKHILDHRTYEVSGGQQQRAACARAI IHNPALILADEPTGNLDSKSAKQVMNTLAQLNEEKEATILLVTHDATAASFCKRIVFI KDGRFFSEIHRGTNRQVFYQSILDTLSVLGGDFHEFENYRP*" gene complement(3431094..3431873) /gene="psdA" /locus_tag="BSU_34700" /old_locus_tag="BSU34700" S_feature complement(3431874..3431955) /Source="Nicolas_S_feature" /locus_tag="new_3566276_3566357_c" /HighExp="LBGtran, M0t45, H2O2, C30, Lbexp, Lbstat, LBGstat, dia0, Paraq, Mt0" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA, SigA" /TUshortPSig="1, 1, 0.997" /TUlongSig="SigA, SigA" /TUlongPSig="1, 0.999" /label="S1321" CDS complement(3431956..3433026) /gene="psdS" /locus_tag="BSU_34710" /old_locus_tag="BSU34710" /function="16.12: Sense" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:11717295, 12432961, 14651641, 21078927, 27997719" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11717295, 12432961, 14651641, 21078927, 27997719; Product type rc: receptor" /codon_start=1 /transl_table=11 /product="two-component sensor histidine kinase [PsdR] response to lantibiotics (nisin and gallidermin)" /protein_id="NP_391351.1" /db_xref="EnsemblGenomes-Gn:BSU34710" /db_xref="EnsemblGenomes-Tr:CAB15476" /db_xref="GOA:O06979" /db_xref="InterPro:IPR003594" /db_xref="InterPro:IPR004358" /db_xref="InterPro:IPR005467" /db_xref="InterPro:IPR036890" /db_xref="SubtiList:BG12406" /db_xref="UniProtKB/Swiss-Prot:O06979" /translation="MLKTYLIDRLAIILFSLLGIGSAMLIAYLSIVESGAEPSKENMM YIWILPGTLLAAGFAADYVRQFSFLTYVKKLAEQASSSNDIGQSLKARKPRTGEQALW TKMINALGQQYESRLSQYINQQKQHYTFTNQWVHHMKTPVSVISLMIQEGKNGTSSSF PTFLEELEDENERFRHGLDMMLQTARLEEFAFDVKPQTFDLAEMVRSLINQEKRQFIK RRLFPTLHVPPNAVQISSDQKWLSFVVEQILFNALKYSKQGVGDPITIRIETQGHETR LSVADEGIGIPPQDLPRIFDAFFTGENGRTMKEATGMGLYLAKQVCSRLGHKLYAESK EGAGTVMTIVFSSDTLVNVTAL*" gene complement(3431956..3433026) /gene="psdS" /locus_tag="BSU_34710" /old_locus_tag="BSU34710" CDS complement(3433020..3433733) /gene="psdR" /locus_tag="BSU_34720" /old_locus_tag="BSU34720" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:11717295, 12432961, 14651641, 21078927, 27997719" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11717295, 12432961, 14651641, 21078927, 27997719; Product type r: regulator" /codon_start=1 /transl_table=11 /product="two-component response regulator [PsdS] responding to lipid II-binding lantibiotics (nisin and gallidermin)" /protein_id="NP_391352.1" /db_xref="EnsemblGenomes-Gn:BSU34720" /db_xref="EnsemblGenomes-Tr:CAB15477" /db_xref="GOA:O06978" /db_xref="InterPro:IPR001789" /db_xref="InterPro:IPR001867" /db_xref="InterPro:IPR011006" /db_xref="InterPro:IPR016032" /db_xref="InterPro:IPR036388" /db_xref="SubtiList:BG12405" /db_xref="UniProtKB/Swiss-Prot:O06978" /translation="MYRILLVEDDERIASLLGGHLQKYGYEVKIAEQLNDIKLEFAEM KPDLVLLDINLPFFDGFYWCRQIRTISNAPIIFISARTDELNQVMAIENGGDDYITKP FHLEVVMAKIKSVLRRTYGEYSPSLPQESRIVELGGLTIYPDQNEAEWNSVRILFSQK EFQLLSIFVREHKKIVSRDELLEALWDDVDFVDDNTLTVNVNRLRRKLENAGLTDCIS TIRGQGYQFQVNRKDEAEC*" gene complement(3433020..3433733) /gene="psdR" /locus_tag="BSU_34720" /old_locus_tag="BSU34720" promotor_-10 complement(3433779..3433798) /Source="Nicolas_upshift_promotors" /id="U2725" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.798201798201798" /psig=1 /xcortree=2304 /SigmaFactorBS="acctttatcattctatcataacaaaaagaaaaagaccGATTt actattccgcaCATGCTATAATAATTTTGGAatcttctagaaaaatcatcgtgatgta c" /listShort="yvcP, yvcQ, S1321, yvcR, yvcS" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3433791) /Source="Nicolas_upshifts" /id="U2725" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.798201798201798" /psig=1 /xcortree=2304 /SigmaFactorBS="acctttatcattctatcataacaaaaagaaaaagaccGATTt actattccgcaCATGCTATAATAATTTTGGAatcttctagaaaaatcatcgtgatgta c" /listShort="yvcP, yvcQ, S1321, yvcR, yvcS" /GFF_Attribute="listLong" S_feature complement(3433793..3434054) /Source="Nicolas_S_feature" /locus_tag="new_3568195_3568456_c" /HighExp="H2O2, G135, G180, Cold, Paraq, G150, dia15, Oxctl, LBGexp, C30" /AntisenseName="yvzJ" /AntisenseCor="0.56014644713727801" /AntisenseRegPval="-22.9" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="1, 0.997" /TUlongSig="SigA, SigA" /TUlongPSig="1, 0.999" /label="S1322" promotor_-35 complement(3433811..3433814) /Source="Nicolas_upshift_promotors" /id="U2725" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.798201798201798" /psig=1 /xcortree=2304 /SigmaFactorBS="acctttatcattctatcataacaaaaagaaaaagaccGATTt actattccgcaCATGCTATAATAATTTTGGAatcttctagaaaaatcatcgtgatgta c" /listShort="yvcP, yvcQ, S1321, yvcR, yvcS" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 3433814..3433821 /Source="Nicolas_upshift_promotors" /id="U2726" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.888111888111888" /psig=1 /xcortree=1902 /SigmaFactorBS="attccaaaattattatagcatgtgcggaatagtaaatCGGTC TTTttctttttgtTATGATAGAATGATAAAGGTaaaattttcataataggcaggtgtc g" /listShort="yvzJ" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3433832..3433851 /Source="Nicolas_upshift_promotors" /id="U2726" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.888111888111888" /psig=1 /xcortree=1902 /SigmaFactorBS="attccaaaattattatagcatgtgcggaatagtaaatCGGTC TTTttctttttgtTATGATAGAATGATAAAGGTaaaattttcataataggcaggtgtc g" /listShort="yvzJ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3433837 /Source="Nicolas_upshifts" /id="U2726" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.888111888111888" /psig=1 /xcortree=1902 /SigmaFactorBS="attccaaaattattatagcatgtgcggaatagtaaatCGGTC TTTttctttttgtTATGATAGAATGATAAAGGTaaaattttcataataggcaggtgtc g" /listShort="yvzJ" /GFF_Attribute="listLong" CDS 3433880..3434089 /gene="yvzJ" /locus_tag="BSU_34729" /old_locus_tag="BSU34729" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type lp: lipoprotein" /codon_start=1 /transl_table=11 /product="putative lipoprotein" /protein_id="YP_003097790.1" /db_xref="EnsemblGenomes-Gn:BSU34729" /db_xref="EnsemblGenomes-Tr:CAX52696" /db_xref="GOA:C0H3R7" /db_xref="UniProtKB/Swiss-Prot:C0H3R7" /translation="MKKIMLFLAMTSILSACQPNYTGKYIEIGDTLTDYTKECFKENE IPYKYEKGKLYIPEDAFDTAIYTCS*" gene 3433880..3434089 /gene="yvzJ" /locus_tag="BSU_34729" /old_locus_tag="BSU34729" downshifts 3434067 /Source="Nicolas_upshifts" /id="D1798" /incds=0 /nref=7 /ntot=138 /MaxReadThrough="1.16039" /MaxDrop="3.61604" /score="-5.58790836" /energy="-11.4" /TU="NA" /idTUdmin="U2726" /TUdmin=0 /isTUend="TRUE" downshifts complement(3434099) /Source="Nicolas_upshifts" /id="D1799" /incds=0 /nref=1 /ntot=3 /MaxReadThrough="3.16808" /MaxDrop="2.84175" /score="16.7711538" /energy="-11.5" /TU="U2727,U2729" /idTUdmin="U2728" /TUdmin=44 /isTUend="FALSE" CDS complement(3434125..3434889) /gene="yvcN" /locus_tag="BSU_34730" /old_locus_tag="BSU34730" /EC_number="2.3.1.-" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 10876241; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative arylamine N-acetyltransferase" /protein_id="NP_391353.1" /db_xref="EnsemblGenomes-Gn:BSU34730" /db_xref="EnsemblGenomes-Tr:CAB15478" /db_xref="GOA:O06977" /db_xref="InterPro:IPR001447" /db_xref="SubtiList:BG12404" /db_xref="UniProtKB/Swiss-Prot:O06977" /translation="MIKMSDFLKDCFQKIGWEKDHVSFGDLPLFLKAMAYRFPFENRA VLAKENYKITKEELWRRLLKDQHGGLCYDLNGFLYFVLREAGFHVKLIRGTVYAGDQE GWALEGTHAAVWLSAENGDYLVDIGFGINLALQPIPLSGETVQSPVGSFRIKKEETEK GSYVLLMDKGEGWQIGYAFTLEESDLGDLDNMKDIIHSHEKSPFNKSLLASKLTPSGR MVMSERHFTIYENGGNIQKSDIGPSGFEEKLNTHFL*" gene complement(3434125..3434889) /gene="yvcN" /locus_tag="BSU_34730" /old_locus_tag="BSU34730" downshifts complement(3434147) /Source="Nicolas_upshifts" /id="D1800" /incds=0 /nref=143 /ntot=253 /MaxReadThrough="3.19848" /MaxDrop="6.45069" /score="16.7711538" /energy="-11.5" /TU="U2727,U2729" /idTUdmin="U2728" /TUdmin="-4" /isTUend="TRUE" CDS complement(3434890..3435147) /gene="crh" /locus_tag="BSU_34740" /old_locus_tag="BSU34740" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:10559153, 10589728, 1136107, 12972249, 15126459, 16411239, 17142398, 21992469, 22092971" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10559153, 10589728, 1136107, 12972249, 15126459, 16411239, 17142398, 21992469, 22092971; Product type r: regulator" /codon_start=1 /transl_table=11 /product="catabolite repression HPr-like protein" /protein_id="NP_391354.1" /db_xref="EnsemblGenomes-Gn:BSU34740" /db_xref="EnsemblGenomes-Tr:CAB15479" /db_xref="InterPro:IPR000032" /db_xref="InterPro:IPR002114" /db_xref="InterPro:IPR035895" /db_xref="PDB:1K1C" /db_xref="PDB:1MO1" /db_xref="PDB:1MU4" /db_xref="PDB:1ZVV" /db_xref="PDB:2AK7" /db_xref="PDB:2RLZ" /db_xref="SubtiList:BG12403" /db_xref="UniProtKB/Swiss-Prot:O06976" /translation="MVQQKVEVRLKTGLQARPAALFVQEANRFTSDVFLEKDGKKVNA KSIMGLMSLAVSTGTEVTLIAQGEDEQEALEKLAAYVQEEV*" gene complement(3434890..3435147) /gene="crh" /locus_tag="BSU_34740" /old_locus_tag="BSU34740" CDS complement(3435171..3436121) /gene="whiA" /locus_tag="BSU_34750" /old_locus_tag="BSU34750" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 10986251, 17603302, 19836336, 24097947; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative morphogen" /protein_id="NP_391355.1" /db_xref="EnsemblGenomes-Gn:BSU34750" /db_xref="EnsemblGenomes-Tr:CAB15480" /db_xref="GOA:O06975" /db_xref="InterPro:IPR003802" /db_xref="InterPro:IPR018478" /db_xref="InterPro:IPR023054" /db_xref="InterPro:IPR027434" /db_xref="InterPro:IPR033981" /db_xref="SubtiList:BG12402" /db_xref="UniProtKB/Swiss-Prot:O06975" /translation="MSFASETKKELTNLEVKDCCINAELSALIRMNGALSFTNRHLVL DVQTENAAIARRIYTLLKKQYDVSVELLVRKKMRLKKNNVYIVRFSENAKAILEDLKI LGENFVFERSISKELVKKRCCKRSYMRGAFLAGGSVNNPETSSYHLEIFSLYKEHNDS LCDLLNEFQLNSKTLERKKGYITYLKEAEKITEFLNVIGAHNSLLRFEDVRIVRDMRN SVNRLVNCETANLNKTIGASLRQVENIKYIDERIGLEALPEKLREIAQLRIDYQEVTL KELGEMVASGKISKSGINHRLRKLDEIAEQLRTGQTVTLK*" gene complement(3435171..3436121) /gene="whiA" /locus_tag="BSU_34750" /old_locus_tag="BSU34750" CDS complement(3436144..3437097) /gene="mgfK" /locus_tag="BSU_34760" /old_locus_tag="BSU34760" /function="16.2: Construct biomass (Anabolism)" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:11888293, 16272399, 21320184, 21371139, 25012659, 27806131, 28646159" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11888293, 16272399, 21320184, 21371139, 25012659, 27806131, 28646159; Product type f: factor" /codon_start=1 /transl_table=11 /product="gluconeogenesis morphogenetic factor (UDP-sugar binding)" /protein_id="NP_391356.2" /db_xref="EnsemblGenomes-Gn:BSU34760" /db_xref="EnsemblGenomes-Tr:CAB15481" /db_xref="GOA:O06974" /db_xref="InterPro:IPR002882" /db_xref="InterPro:IPR010119" /db_xref="SubtiList:BG12401" /db_xref="UniProtKB/Swiss-Prot:O06974" /translation="MGQKPKIAIFGGGTGLSVLLRGLKHKPVDITAIVTVADDGGSSG RLRNELKIPPPGDIRNVLAALSDVEPLVEDLFQHRFNKGNDLTGHSLGNLILAAMTNI TGDFFHAVTEMSKVLNVRGKVLPAANASVVLHAEMEDGRVVSGESTIPEYGQRIKRVF LTPEQIDPLPETIDVIREADLIIIGPGSLYTSILPNLLVPKIGEEVIKAPAKKVYICN VMTQPGETLHYTAADHVKALNQHMGCGFIDTILVNSEDIPDEIKRKYEMESARPVDFD IEELKAMGLEVIRDQIVTYKNDVIRHDTHKVASLLVDLLKE*" gene complement(3436144..3437097) /gene="mgfK" /locus_tag="BSU_34760" /old_locus_tag="BSU34760" CDS complement(3437099..3437986) /gene="yvcJ" /locus_tag="BSU_34770" /old_locus_tag="BSU34770" /function="15.6: DNA transformation" /experiment="publication(s) with functional evidences, PMID:18334534, 19074378, 21179021, 21709426" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 18334534, 19074378, 21179021, 21709426; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="GTPase possibly involved in regulator sRNA degradation" /protein_id="NP_391357.1" /db_xref="EnsemblGenomes-Gn:BSU34770" /db_xref="EnsemblGenomes-Tr:CAB15482" /db_xref="GOA:O06973" /db_xref="InterPro:IPR005337" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG12400" /db_xref="UniProtKB/Swiss-Prot:O06973" /translation="MSVSESHDIQLVIITGMSGAGKTVAIQSFEDLGYFCVDNLPPSL LPKFLELMKESNSKMSKVALVMDLRGREFFDRLIEALDEMAENPWITPRILFLDAKDS ILVTRYKETRRSHPLAATGLPLEGIALERELLEELKGRSQIIYDTSDMKPRDLREKIV KHFATNQGETFTVNVMSFGFKYGIPIDADLVFDVRFLPNPYYIESMRPLTGKDKEVSS YVMKWNETQKFNEKLIDLLSFMLPSYKREGKSQVVIAIGCTGGQHRSVTLAENLADYF KKDYYTHVTHRDIEKRSRK*" gene complement(3437099..3437986) /gene="yvcJ" /locus_tag="BSU_34770" /old_locus_tag="BSU34770" CDS complement(3438011..3438487) /gene="yvcI" /locus_tag="BSU_34780" /old_locus_tag="BSU34780" /EC_number="3.6.-.-" /function="16.8: Protect" /function="16.11: Scavenge (Catabolism)" /function="16.3: Control" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative triphosphate pyrophosphate hydrolase" /protein_id="NP_391358.1" /db_xref="EnsemblGenomes-Gn:BSU34780" /db_xref="EnsemblGenomes-Tr:CAB15483" /db_xref="GOA:O06972" /db_xref="InterPro:IPR000086" /db_xref="InterPro:IPR015797" /db_xref="InterPro:IPR020476" /db_xref="SubtiList:BG12399" /db_xref="UniProtKB/Swiss-Prot:O06972" /translation="MTYLQRVTNCVLQTDDKVLLLQKPRRGWWVAPGGKMESGESVRD SVIREYREETGIYIINPQLKGVFTFIIKDGDHIVSEWMMFTFVADSYTGQNVSESEEG KLQWHDVNDIQNLPMAPGDGHILDFMMKGQGLLHGTFTYTPEFELLSYRLDPQHIK*" gene complement(3438011..3438487) /gene="yvcI" /locus_tag="BSU_34780" /old_locus_tag="BSU34780" promotor_-10 complement(3438507..3438526) /Source="Nicolas_upshift_promotors" /id="U2727" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.588411588411588" /psig=1 /xcortree=2664 /SigmaFactorBS="ctgtaaaatagaagaaaagattgtcaatgtctcttCATTGtg ggaggcatcttgaAGCGGTATAATAAAGAGACGatgacaggacgaaggttaggtgacg t" /listShort="yvcI, yvcJ, yvcK, whiA, crh, yvcN, S1322, yvcP, yvcQ, S1321, yvcR" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3438521) /Source="Nicolas_upshifts" /id="U2727" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.588411588411588" /psig=1 /xcortree=2664 /SigmaFactorBS="ctgtaaaatagaagaaaagattgtcaatgtctcttCATTGtg ggaggcatcttgaAGCGGTATAATAAAGAGACGatgacaggacgaaggttaggtgacg t" /listShort="yvcI, yvcJ, yvcK, whiA, crh, yvcN, S1322, yvcP, yvcQ, S1321, yvcR" /GFF_Attribute="listLong" promotor_-35 complement(3438542..3438546) /Source="Nicolas_upshift_promotors" /id="U2727" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.588411588411588" /psig=1 /xcortree=2664 /SigmaFactorBS="ctgtaaaatagaagaaaagattgtcaatgtctcttCATTGtg ggaggcatcttgaAGCGGTATAATAAAGAGACGatgacaggacgaaggttaggtgacg t" /listShort="yvcI, yvcJ, yvcK, whiA, crh, yvcN, S1322, yvcP, yvcQ, S1321, yvcR" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(3438565..3438584) /Source="Nicolas_upshift_promotors" /id="U2728" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.572427572427572" /psig="0.982017982017982" /xcortree=1583 /SigmaFactorBS="ataaataaaagagaattccagttacagcaaaatcatCTGAat taaggaatgaatATGCTGTAAAATAGAAGAAAagattgtcaatgtctcttcattgtgg g" /listShort="yvcI, yvcJ, yvcK, whiA, crh, yvcN" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3438578) /Source="Nicolas_upshifts" /id="U2728" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.572427572427572" /psig="0.982017982017982" /xcortree=1583 /SigmaFactorBS="ataaataaaagagaattccagttacagcaaaatcatCTGAat taaggaatgaatATGCTGTAAAATAGAAGAAAagattgtcaatgtctcttcattgtgg g" /listShort="yvcI, yvcJ, yvcK, whiA, crh, yvcN" /GFF_Attribute="listLong" promotor_-35 complement(3438599..3438602) /Source="Nicolas_upshift_promotors" /id="U2728" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.572427572427572" /psig="0.982017982017982" /xcortree=1583 /SigmaFactorBS="ataaataaaagagaattccagttacagcaaaatcatCTGAat taaggaatgaatATGCTGTAAAATAGAAGAAAagattgtcaatgtctcttcattgtgg g" /listShort="yvcI, yvcJ, yvcK, whiA, crh, yvcN" /GFF_Attribute="listLong" /label="promotor_-35" S_feature complement(3438654..3438804) /Source="Nicolas_S_feature" /locus_tag="new_3573056_3573206_c" /HighExp="dia15, Diami, dia5, H2O2, Etha, LPhT, Cold, Paraq, C30, B60" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="0.997, 1" /TUlongSig="SigA" /TUlongPSig="0.999" /label="S1323" downshifts complement(3438697) /Source="Nicolas_upshifts" /id="D1801" /incds=0 /nref=9 /ntot=78 /MaxReadThrough="6.94979" /MaxDrop="3.73811" /score="11.9453839" /energy="-11" /TU="U2729,U2733" /idTUdmin="U2734" /TUdmin=2904 /isTUend="FALSE" CDS complement(3438805..3439755) /gene="trxB" /locus_tag="BSU_34790" /old_locus_tag="BSU34790" /EC_number="1.8.1.9" /function="16.6: Maintain" /function="16.10: Respire" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:12682299, 14597697, 15659166, 23813734, 24401092" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12682299, 14597697, 15659166, 23813734, 24401092; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="thioredoxin reductase" /protein_id="NP_391359.1" /db_xref="EnsemblGenomes-Gn:BSU34790" /db_xref="EnsemblGenomes-Tr:CAB15484" /db_xref="GOA:P80880" /db_xref="InterPro:IPR000103" /db_xref="InterPro:IPR005982" /db_xref="InterPro:IPR008255" /db_xref="InterPro:IPR023753" /db_xref="InterPro:IPR036188" /db_xref="SubtiList:BG12398" /db_xref="UniProtKB/Swiss-Prot:P80880" /translation="MSEEKIYDVIIIGAGPAGMTAAVYTSRANLSTLMIERGIPGGQM ANTEDVENYPGFESILGPELSNKMFEHAKKFGAEYAYGDIKEVIDGKEYKVVKAGSKE YKARAVIIAAGAEYKKIGVPGEKELGGRGVSYCAVCDGAFFKGKELVVVGGGDSAVEE GVYLTRFASKVTIVHRRDKLRAQSILQARAFDNEKVDFLWNKTVKEIHEENGKVGNVT LVDTVTGEESEFKTDGVFIYIGMLPLSKPFENLGITNEEGYIETNDRMETKVEGIFAA GDIREKSLRQIVTATGDGSIAAQSVQHYVEELQETLKTLK*" gene complement(3438805..3439755) /gene="trxB" /locus_tag="BSU_34790" /old_locus_tag="BSU34790" S_feature complement(3439756..3439843) /Source="Nicolas_S_feature" /locus_tag="new_3574158_3574245_c" /HighExp="dia5, Diami, dia15, H2O2, Etha, Salt, Cold, Paraq, LPhT, Oxctl" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="0.997, 1" /TUlongSig="SigA" /TUlongPSig="0.999" /label="S1324" promotor_-10 complement(3439832..3439851) /Source="Nicolas_upshift_promotors" /id="U2729" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.507492507492508" /psig="0.997002997002997" /xcortree=2036 /SigmaFactorBS="ttttcgaatacatttaatcgtgttgagcaaaaaaATAGcgta tcaccatgagATTTTATAGGATATGGGTAAggaatacgtttgatggggattcttatct t" /listShort="S1324, trxB, S1323, yvcI, yvcJ, yvcK, whiA, crh, yvcN, S1322, yvcP, yvcQ, S1321, yvcR, yvcS" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3439843) /Source="Nicolas_upshifts" /id="U2729" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.507492507492508" /psig="0.997002997002997" /xcortree=2036 /SigmaFactorBS="ttttcgaatacatttaatcgtgttgagcaaaaaaATAGcgta tcaccatgagATTTTATAGGATATGGGTAAggaatacgtttgatggggattcttatct t" /listShort="S1324, trxB, S1323, yvcI, yvcJ, yvcK, whiA, crh, yvcN, S1322, yvcP, yvcQ, S1321, yvcR, yvcS" /GFF_Attribute="listLong" S_feature complement(3439845..3439936) /Source="Nicolas_S_feature" /locus_tag="new_3574247_3574338_c" /HighExp="Cold, Oxctl, G180, G135, Paraq, C30, LBGexp, G150, S1, H2O2" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="SigA" /TUlongPSig="0.999" /label="S1325" promotor_-35 complement(3439866..3439869) /Source="Nicolas_upshift_promotors" /id="U2729" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.507492507492508" /psig="0.997002997002997" /xcortree=2036 /SigmaFactorBS="ttttcgaatacatttaatcgtgttgagcaaaaaaATAGcgta tcaccatgagATTTTATAGGATATGGGTAAggaatacgtttgatggggattcttatct t" /listShort="S1324, trxB, S1323, yvcI, yvcJ, yvcK, whiA, crh, yvcN, S1322, yvcP, yvcQ, S1321, yvcR, yvcS" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 3439884..3439890 /Source="Nicolas_upshift_promotors" /id="U2730" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=199 /SigmaFactorBS="gtgatacgctatttttttgctcaacaCGATTAAatgtattcg aaaaGGGTATATGTTAATAAAGAaagagccttctgtttatagaaggcccttgtcatat t" /listShort="S1326" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3439904..3439922 /Source="Nicolas_upshift_promotors" /id="U2730" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=199 /SigmaFactorBS="gtgatacgctatttttttgctcaacaCGATTAAatgtattcg aaaaGGGTATATGTTAATAAAGAaagagccttctgtttatagaaggcccttgtcatat t" /listShort="S1326" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3439918 /Source="Nicolas_upshifts" /id="U2730" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=199 /SigmaFactorBS="gtgatacgctatttttttgctcaacaCGATTAAatgtattcg aaaaGGGTATATGTTAATAAAGAaagagccttctgtttatagaaggcccttgtcatat t" /listShort="S1326" /GFF_Attribute="listLong" S_feature 3439919..3443305 /Source="Nicolas_S_feature" /locus_tag="new_3574321_3577707" /HighExp="Sw, M9-stat, B60, T0.30H, Gly, BC, B36, T1.0H, Salt, C30" /AntisenseName="yvcD" /AntisenseCor="-0.261780844003138" /AntisenseRegPval="-4.9000000000000004" /CDS_PredictionProba="NA" /TUshortSig="SigB" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1326" CDS complement(3439961..3441382) /gene="cwlO" /locus_tag="BSU_34800" /old_locus_tag="BSU34800" /EC_number="3.4.-.-" /function="16.13: Shape" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:15187182, 16233686, 21478646, 22139507, 23855774, 24163346, 24769902" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15187182, 16233686, 21478646, 22139507, 23855774, 24163346, 24769902; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="secreted cell wall DL-endopeptidase" /protein_id="NP_391360.1" /db_xref="EnsemblGenomes-Gn:BSU34800" /db_xref="EnsemblGenomes-Tr:CAB15485" /db_xref="GOA:P40767" /db_xref="InterPro:IPR000064" /db_xref="SubtiList:BG11023" /db_xref="UniProtKB/Swiss-Prot:P40767" /translation="MRKSLITLGLASVIGTSSFLIPFTSKTASAETLDEKKQKIESKQ SEVASSIEAKEKELTELQENQSKIEKELKDINDKALDTSNKIEDKKEENDKTKEEIKK LKKEIKETEARIEKRNEILKKRVRSLQESGGSQGYIDVLLGSTSFGDFISRATAVSSI VDADKDLIKQQEQDKAKLEDSEADLNDKLKEVQAALAKLETMQKDLDKQLNEKDKLFD EAKASQKKTAKAISELKSEASELANQKANTEAEQARIKKEQEAAAALIKKQEEAQKAS DETQTDDSQTATTESSKASSSDDSSDNSSDNSSNGSSNSSSNGSSSKKSSGSNSNSGG TVISNSGGIEGAISVGSSIVGQSPYKFGGGRTQSDINNRIFDCSSFVRWAYASAGVNL GPVGGTTTDTLVGRGQAVSASEMKRGDLVFFDTYKTNGHVGIYLGNGTFLNDNTSHGV SVDSMSNPYWKAAFKGVVRRVVQ*" gene complement(3439961..3441382) /gene="cwlO" /locus_tag="BSU_34800" /old_locus_tag="BSU34800" downshifts complement(3439981) /Source="Nicolas_upshifts" /id="D1802" /incds=0 /nref=8 /ntot=106 /MaxReadThrough="6.31311" /MaxDrop="3.4602" /score="1.76249731" /energy="-12.1" /TU="U2733" /idTUdmin="U2734" /TUdmin=1620 /isTUend="FALSE" downshifts complement(3440105) /Source="Nicolas_upshifts" /id="D1803" /incds=1 /nref=1 /ntot=20 /MaxReadThrough="7.07718" /MaxDrop="2.13349" /score="1.76249731" /energy="-12.1" /TU="U2733" /idTUdmin="U2734" /TUdmin=1496 /isTUend="FALSE" misc_feature 3441009..3441013 /Source="Nicolas_upshift_promotors" /id="U2731" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.963036963036963" /psig="0.002997002997003" /xcortree=52 /SigmaFactorBS="aaagaacatctatgtatccttgagatccgccgctttcctgta aagaacgaACGCGttttttcaggatttcattgcgtttttcgatgcgtgcttcagtttc t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 3441019 /Source="Nicolas_upshifts" /id="U2731" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.963036963036963" /psig="0.002997002997003" /xcortree=52 /SigmaFactorBS="aaagaacatctatgtatccttgagatccgccgctttcctgta aagaacgaACGCGttttttcaggatttcattgcgtttttcgatgcgtgcttcagtttc t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" misc_feature 3441298..3441302 /Source="Nicolas_upshift_promotors" /id="U2732" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.84015984015984" /psig="0.130869130869131" /xcortree=42 /SigmaFactorBS="ctcagattgcttgctttcgattttttgtttcttttcatctaa tgtttccgccgATGCAgttttacttgtaaatgggatcaaaaaactgcttgtcccgatg a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 3441305 /Source="Nicolas_upshifts" /id="U2732" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.84015984015984" /psig="0.130869130869131" /xcortree=42 /SigmaFactorBS="ctcagattgcttgctttcgattttttgtttcttttcatctaa tgtttccgccgATGCAgttttacttgtaaatgggatcaaaaaactgcttgtcccgatg a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" S_feature complement(3441383..3441580) /Source="Nicolas_S_feature" /locus_tag="new_3575785_3575982_c" /HighExp="S1, Cold, T-3.40H, M9-exp, MG t5, MG 5, MG 15, T-5.40H, GM-0.2, MG-0.2" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="SigA" /TUlongPSig="0.999" /label="S1327" downshifts 3441503 /Source="Nicolas_upshifts" /id="D1804" /incds=0 /nref=2 /ntot=119 /MaxReadThrough="6.41604" /MaxDrop="3.8522" /score="6.14322693" /energy="-7.6" /TU="U2730,U2731" /idTUdmin="U2731" /TUdmin="-1408" /isTUend="FALSE" promotor_-10 complement(3441568..3441587) /Source="Nicolas_upshift_promotors" /id="U2733" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.431568431568432" /psig=1 /xcortree=2537 /SigmaFactorBS="catctgtttgaaacataaatgtaataaaatttatCGCTAATT tgtcgaaacttGATGGTATAATGATTCTCGTacataaggaattagtgttttttacata t" /listShort="S1327, cwlO, S1325, S1324, trxB, S1323, yvcI, yvcJ, yvcK, whiA, crh, yvcN" /listLong="S1322, yvcP, yvcQ, S1321, yvcR, yvcS" /label="promotor_-10" upshifts complement(3441580) /Source="Nicolas_upshifts" /id="U2733" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.431568431568432" /psig=1 /xcortree=2537 /SigmaFactorBS="catctgtttgaaacataaatgtaataaaatttatCGCTAATT tgtcgaaacttGATGGTATAATGATTCTCGTacataaggaattagtgttttttacata t" /listShort="S1327, cwlO, S1325, S1324, trxB, S1323, yvcI, yvcJ, yvcK, whiA, crh, yvcN" /listLong="S1322, yvcP, yvcQ, S1321, yvcR, yvcS" promotor_-35 complement(3441599..3441606) /Source="Nicolas_upshift_promotors" /id="U2733" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.431568431568432" /psig=1 /xcortree=2537 /SigmaFactorBS="catctgtttgaaacataaatgtaataaaatttatCGCTAATT tgtcgaaacttGATGGTATAATGATTCTCGTacataaggaattagtgttttttacata t" /listShort="S1327, cwlO, S1325, S1324, trxB, S1323, yvcI, yvcJ, yvcK, whiA, crh, yvcN" /listLong="S1322, yvcP, yvcQ, S1321, yvcR, yvcS" /label="promotor_-35" CDS complement(3441763..3443217) /gene="yvcD" /locus_tag="BSU_34810" /old_locus_tag="BSU34810" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_391361.1" /db_xref="EnsemblGenomes-Gn:BSU34810" /db_xref="EnsemblGenomes-Tr:CAB15486" /db_xref="InterPro:IPR011990" /db_xref="InterPro:IPR013026" /db_xref="InterPro:IPR019734" /db_xref="SubtiList:BG12396" /db_xref="UniProtKB/Swiss-Prot:O06968" /translation="MGKHTSEHKNHAQIVQLLQDGQYFFHKGLKAYKERNLKRASKLI QRAVHLEPEDSEMLSQLAVIYSEMGQYQESNDLLDYIMANLEAEMPECHYFKANNFAH LGLFQEAYKEAAAYSDADPDGEFAEENDSLLDLLDLGDDGIEDSLYDQDELLVKQDRA KSLLESGQLAEAVAALEEITTEYPELWSAYNNLALAYFYSGNVVKAKQTAYEVLSHNE GNLHALCNLLVFYYYEREDEKVAELSDQLSNVYPMLLEQRYKLGATLALVGRYEIGYK WLKSLYKTGFEGDDTFFYWLSCSAYFTGHTDFAETIWRKVESQYPGEDRPAPWIERRE ALPSSVEQRLAAYYISSTKGETEHLEAVIRSKRITAPFETHFVKLLLNGDSAAADVSE DALFAYQTVKLLEQAEKEEMKTEVMSCWVFHVIQQIRAAAPLKNEKGWAAAICYIWKE AHGKQDTKKDTAARFGISPATLTKYMKYIDDILE*" gene complement(3441763..3443217) /gene="yvcD" /locus_tag="BSU_34810" /old_locus_tag="BSU34810" downshifts complement(3441783) /Source="Nicolas_upshifts" /id="D1805" /incds=0 /nref=11 /ntot=190 /MaxReadThrough="3.36188" /MaxDrop="3.98985" /score="16.3455178" /energy="-9.1" /TU="U2734" /idTUdmin="U2734" /TUdmin="-182" /isTUend="FALSE" S_feature complement(3443218..3443342) /Source="Nicolas_S_feature" /locus_tag="new_3577620_3577744_c" /HighExp="LBGstat, Sw, Cold, BC, BI, Lbexp, dia0, G150, LBGtran, M40t45" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S1328" downshifts 3443263 /Source="Nicolas_upshifts" /id="D1806" /incds=0 /nref=4 /ntot=36 /MaxReadThrough="1.81602" /MaxDrop="3.41181" /score="7.59889121" /energy="-9.9" /TU="NA" /idTUdmin="U2730" /TUdmin=0 /isTUend="TRUE" CDS complement(3443343..3445112) /gene="bmrA" /locus_tag="BSU_34820" /old_locus_tag="BSU34820" /EC_number="3.6.3.-" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:16405427, 18215075, 21077936, 22711831, 24630999" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16405427, 18215075, 21077936, 22711831, 24630999; Product type t : transporter" /codon_start=1 /transl_table=11 /product="efflux transporter (ATP-binding and permease protein)" /protein_id="NP_391362.1" /db_xref="EnsemblGenomes-Gn:BSU34820" /db_xref="EnsemblGenomes-Tr:CAB15487" /db_xref="GOA:O06967" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR011527" /db_xref="InterPro:IPR017871" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR036640" /db_xref="SubtiList:BG12395" /db_xref="UniProtKB/Swiss-Prot:O06967" /translation="MPTKKQKSKSKLKPFFALVRRTNPSYGKLAFALALSVVTTLVSL LIPLLTKQLVDGFSMSNLSGTQIGLIALVFFVQAGLSAYATYALNYNGQKIISGLREL LWKKLIKLPVSYFDTNASGETVSRVTNDTMVVKELITTHISGFITGIISVIGSLTILF IMNWKLTLLVLVVVPLAALILVPIGRKMFSISRETQDETARFTGLLNQILPEIRLVKA SNAEDVEYGRGKMGISSLFKLGVREAKVQSLVGPLISLVLMAALVAVIGYGGMQVSSG ELTAGALVAFILYLFQIIMPMGQITTFFTQLQKSIGATERMIEILAEEEEDTVTGKQI ENAHLPIQLDRVSFGYKPDQLILKEVSAVIEAGKVTAIVGPSGGGKTTLFKLLERFYS PTAGTIRLGDEPVDTYSLESWREHIGYVSQESPLMSGTIRENICYGLERDVTDAEIEK AAEMAYALNFIKELPNQFDTEVGERGIMLSGGQRQRIAIARALLRNPSILMLDEATSS LDSQSEKSVQQALEVLMEGRTTIVIAHRLSTVVDADQLLFVEKGEITGRGTHHELMAS HGLYRDFAEQQLKMNADLENKAG*" gene complement(3443343..3445112) /gene="bmrA" /locus_tag="BSU_34820" /old_locus_tag="BSU34820" S_feature complement(3445113..3445187) /Source="Nicolas_S_feature" /locus_tag="new_3579515_3579589_c" /HighExp="LBGstat, Cold, Lbexp, G150, Oxctl, dia0, T1.30H, T0.30H, BC, T1.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S1329" misc_feature complement(3445176..3445195) /Source="Nicolas_upshift_promotors" /id="U2734" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.756243756243756" /psig="0.999000999001" /xcortree=2142 /SigmaFactorBS="gggagatttttattttgatcacggcaaaaatatactgaaaaa gtctttctccATTGATATGATTGAGAAAGAgtaaaaatcatccttttgctatgacttt t" /listShort="S1329, bmrA, S1328, yvcD" /listLong="S1327, cwlO, S1325, S1324, trxB, S1323, yvcI, yvcJ, yvcK, whiA, crh, yvcN, S1322, yvcP, yvcQ, S1321, yvcR, yvcS" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(3445187) /Source="Nicolas_upshifts" /id="U2734" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.756243756243756" /psig="0.999000999001" /xcortree=2142 /SigmaFactorBS="gggagatttttattttgatcacggcaaaaatatactgaaaaa gtctttctccATTGATATGATTGAGAAAGAgtaaaaatcatccttttgctatgacttt t" /listShort="S1329, bmrA, S1328, yvcD" /listLong="S1327, cwlO, S1325, S1324, trxB, S1323, yvcI, yvcJ, yvcK, whiA, crh, yvcN, S1322, yvcP, yvcQ, S1321, yvcR, yvcS" CDS complement(3445277..3445636) /gene="yvzA" /locus_tag="BSU_34830" /old_locus_tag="BSU34830" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_391363.1" /db_xref="EnsemblGenomes-Gn:BSU34830" /db_xref="EnsemblGenomes-Tr:CAB15488" /db_xref="SubtiList:BG14157" /db_xref="UniProtKB/Swiss-Prot:O32265" /translation="MTSLFSESETEIVSTTYMFLTQDEMKGKAGTLNQPINDFLSLTK KFESSLKEEIKGQKGLIVKKIKKELESNSEKRKAALQMIKEEHTAKVDRYKMIIEDLR QQDVTLTYRKKKPVKDV*" gene complement(3445277..3445636) /gene="yvzA" /locus_tag="BSU_34830" /old_locus_tag="BSU34830" downshifts complement(3445297) /Source="Nicolas_upshifts" /id="D1807" /incds=0 /nref=146 /ntot=246 /MaxReadThrough="2.52417" /MaxDrop="4.81771" /score="18.5636016" /energy="-13.2" /TU="NA" /idTUdmin="U2735" /TUdmin=0 /isTUend="TRUE" CDS complement(3445651..3447561) /gene="yvcB" /locus_tag="BSU_34840" /old_locus_tag="BSU34840" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_391364.1" /db_xref="EnsemblGenomes-Gn:BSU34840" /db_xref="EnsemblGenomes-Tr:CAB15489" /db_xref="SubtiList:BG12394" /db_xref="UniProtKB/Swiss-Prot:O06966" /translation="MGNKNVFENENVKLRLIDLEYDYKQKFASTIASEVKKAKKDFEA DIRRIYKEETHHDLPENMKIEIYTSNELVNQNTSIQSSTRESGYDGTAIHIIDEKKHI DQLQIISEGSADNKDWSYNFFGLFLGIDHSQYEATKEFTNKAKKAAGNSEDLKTFALG HSLANNNQVMVQLIDGEYDEVYGVNGAQVNIDQLLETDESLYRYVIRKFSYKYEDIDS IPPEKLKKEIQKYYEDKGVTTNITQRISKDDPLYGVSGKADFITFGDVKMADTNTSVK GIRNIMDGVPDEDVRSIQKFLQKYKDDYEKDGLNGFIKAASGIDIDLIEKVKNTDGAL KKVSVLYEHFDDVKQMYGRIKEELPSFLGFLHTLLRNSGPVVDQLAENGYIDETQKKV IKKELTNINASMRGIESRYEHFIDHLKHGQFMQALKDVGEIVDYVKSILSSLKTLDTE TKDALKLIVDGHSIVQMLNALSKEKGFSYKGSDIYFTGKSGSGETIQVNLSSAVRIYQ NGMKIVEDMEDAISKYQKVYSQEIDEDFIDKKQAIITAIHHMEENPSHYAFDLQFRLA AGFSHTFDKLEKISVHESFHTGALPANDGIVAELKKQTTEKRDFIKNIRESIEKLFEK EEMISQLFDFQS*" gene complement(3445651..3447561) /gene="yvcB" /locus_tag="BSU_34840" /old_locus_tag="BSU34840" CDS complement(3447563..3448288) /gene="yvcA" /locus_tag="BSU_34850" /old_locus_tag="BSU34850" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 17590234; Product type lp: lipoprotein" /codon_start=1 /transl_table=11 /product="putative lipoprotein" /protein_id="NP_391365.1" /db_xref="EnsemblGenomes-Gn:BSU34850" /db_xref="EnsemblGenomes-Tr:CAB15490" /db_xref="GOA:O06965" /db_xref="SubtiList:BG12393" /db_xref="UniProtKB/Swiss-Prot:O06965" /translation="MKKIIFICFSLLLALTGGCSMNDNDKNSTNDNKTEAVKPKDMDP KDLPQVPAFQDEKTREYMVSTKEEEPGYYLLESKLKGFRMLFPEDGKYLSRRSSLTGK NKESIGFNSYDKDTNVMFDGHVTYYKEESFANEPKTMLDIVSGKNDYKGEYKKSSKKK TDIYTAKKKDIFDDIDRKYNYSYSYFGYVKSTEEDNLGVEYAFTLGCKNENQPCSLDE EKAKNKVEKLINSITFLIDKKEK*" gene complement(3447563..3448288) /gene="yvcA" /locus_tag="BSU_34850" /old_locus_tag="BSU34850" S_feature complement(3448289..3448377) /Source="Nicolas_S_feature" /locus_tag="new_3582691_3582779_c" /HighExp="T1.30H, T0.30H, T1.0H, T2.0H, T2.30H, T3.0H, T-1.40H, T-1.10H, MG 150, HiOs" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="0.982, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S1330" promotor_-10 complement(3448377..3448396) /Source="Nicolas_upshift_promotors" /id="U2735" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.446553446553447" /psig="0.982017982017982" /xcortree=2982 /SigmaFactorBS="tcaaaaccgagtctcatttcctATTTatccaaattccgccaT GATGTAACATGAAAAAGGAtgaaataatcatctcttaaccaggtcaatagaattattt t" /listShort="S1330, yvcA, yvcB, yvzA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3448377) /Source="Nicolas_upshifts" /id="U2735" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.446553446553447" /psig="0.982017982017982" /xcortree=2982 /SigmaFactorBS="tcaaaaccgagtctcatttcctATTTatccaaattccgccaT GATGTAACATGAAAAAGGAtgaaataatcatctcttaaccaggtcaatagaattattt t" /listShort="S1330, yvcA, yvcB, yvzA" /GFF_Attribute="listLong" S_feature complement(3448379..3448508) /Source="Nicolas_S_feature" /locus_tag="new_3582781_3582910_c" /HighExp="Etha, Diami, HiTm, T1.0H, Cold, MG 15, T0.30H, BMM, T1.30H, MG 10" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1331" promotor_-35 complement(3448412..3448415) /Source="Nicolas_upshift_promotors" /id="U2735" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.446553446553447" /psig="0.982017982017982" /xcortree=2982 /SigmaFactorBS="tcaaaaccgagtctcatttcctATTTatccaaattccgccaT GATGTAACATGAAAAAGGAtgaaataatcatctcttaaccaggtcaatagaattattt t" /listShort="S1330, yvcA, yvcB, yvzA" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3448534..3449163) /gene="hisIE" /locus_tag="BSU_34860" /old_locus_tag="BSU34860" /EC_number="3.5.4.19" /EC_number="3.6.1.31" /function="16.2: Construct biomass (Anabolism)" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 15871048, 17767732; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="bifunctional phosphoribosyl-AMP cyclohydrolase; phosphoribosyl-ATP pyrophosphohydrolase" /protein_id="NP_391366.1" /db_xref="EnsemblGenomes-Gn:BSU34860" /db_xref="EnsemblGenomes-Tr:CAB15491" /db_xref="GOA:O34912" /db_xref="InterPro:IPR002496" /db_xref="InterPro:IPR008179" /db_xref="InterPro:IPR021130" /db_xref="InterPro:IPR023019" /db_xref="InterPro:IPR026660" /db_xref="SubtiList:BG12603" /db_xref="UniProtKB/Swiss-Prot:O34912" /translation="MKQADELRFNEDGLIPAIVQDAASKEVLTLAYMNKESYEKTLET KETWFYSRSRQALWHKGETSGNTQAVKGIRYDCDQDALLVLVEPSGPACHTGSYSCFT KEQTEEQAADRFGIMNELERVIAERQAEMPEGAYTTYLFREGVDKILKKVGEEASEVI IAAKNRDHEELKWEAADLLYHLLVLLREQSLPLDDVLDVLKKRHSEIEE*" gene complement(3448534..3449163) /gene="hisIE" /locus_tag="BSU_34860" /old_locus_tag="BSU34860" downshifts complement(3448553) /Source="Nicolas_upshifts" /id="D1808" /incds=0 /nref=104 /ntot=178 /MaxReadThrough="4.37156" /MaxDrop="4.76747" /score="14.9565762" /energy="-8.4" /TU="U2738" /idTUdmin="U2735" /TUdmin="-3256" /isTUend="FALSE" CDS complement(3449160..3449918) /gene="hisF" /locus_tag="BSU_34870" /old_locus_tag="BSU34870" /EC_number="4.3.1.-" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 1400209, 17767732, 19636909; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="imidazole glycerol phosphate synthase subunit" /protein_id="NP_391367.1" /db_xref="EnsemblGenomes-Gn:BSU34870" /db_xref="EnsemblGenomes-Tr:CAB15492" /db_xref="GOA:O34727" /db_xref="InterPro:IPR004651" /db_xref="InterPro:IPR006062" /db_xref="InterPro:IPR011060" /db_xref="InterPro:IPR013785" /db_xref="SubtiList:BG12600" /db_xref="UniProtKB/Swiss-Prot:O34727" /translation="MITKRIIPCLDVKEGRVVKGIQFLELKDAGDPVELAEVYDREGA DELVFLDISASHEGRKTMVDVVEQVAAKLAIPFTVGGGINQLSDMKTILRAGADKVSV NTAAVLRPELITEGAEFFGSQCIVLAIDAKYDKESDTYKVYTHGGRKKTDWEVTAWAK EGVKRGAGEILLTSMDSDGEKKGFDHTLTKLVSEAVPVPVIASGGAGNAQHMLEAFTK GEADAALAASIFHYKETSIKEVKSYLKEYGVNVR*" gene complement(3449160..3449918) /gene="hisF" /locus_tag="BSU_34870" /old_locus_tag="BSU34870" CDS complement(3449915..3450652) /gene="hisA" /locus_tag="BSU_34880" /old_locus_tag="BSU34880" /EC_number="5.3.1.16" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 1400209, 26294764; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase" /protein_id="NP_391368.1" /db_xref="EnsemblGenomes-Gn:BSU34880" /db_xref="EnsemblGenomes-Tr:CAB15493" /db_xref="GOA:O35006" /db_xref="InterPro:IPR006062" /db_xref="InterPro:IPR006063" /db_xref="InterPro:IPR011060" /db_xref="InterPro:IPR013785" /db_xref="InterPro:IPR023016" /db_xref="SubtiList:BG12597" /db_xref="UniProtKB/Swiss-Prot:O35006" /translation="MSAFTLYPAIDMRNGKCVRLVQGDYNKETIYGDSPYDMAELFEK EGAEWIHLVDLDGAKEGKRVNDRHVIEIAQKLNLKVEIGGGIRSENDVYEYLSAGVER VILGSSAVSNPPFVKKMLKQYGEKIAIGLDARNGFVSTEGWLETSTLKATELGKELAN EGAEVFIFTDIATDGMLSGPNVKSTVELAKETGKSVIASGGVSSVADLEALARNEADG VSGAIIGKALYTNQFTLSEALERVKRK*" gene complement(3449915..3450652) /gene="hisA" /locus_tag="BSU_34880" /old_locus_tag="BSU34880" CDS complement(3450649..3451287) /gene="hisH" /locus_tag="BSU_34890" /old_locus_tag="BSU34890" /EC_number="2.4.2.-" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:14585832, 15301532" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 14585832, 15301532; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="imidazole glycerol phosphate synthase, glutamineamidotransferase subunit" /protein_id="NP_391369.1" /db_xref="EnsemblGenomes-Gn:BSU34890" /db_xref="EnsemblGenomes-Tr:CAB15494" /db_xref="GOA:O34565" /db_xref="InterPro:IPR010139" /db_xref="InterPro:IPR017926" /db_xref="InterPro:IPR029062" /db_xref="SubtiList:BG12602" /db_xref="UniProtKB/Swiss-Prot:O34565" /translation="MIGVIDYGMGNLYSVSKALERVGVPYFVSEKPEELKEADAFILP GVGSFGDAMDNLGYTKLDQLIHDMVSEGRLLLGICLGMQLLFEESEENGTASGLGLLK GKAVRLKAEDEKGNKLKVPHMGWNRLSFHNESPLLTKTEQGYAYFVHSYYIDGMEENA LLASADYGVRVPAVVGKRNVFGAQFHPEKSSTVGMSILTQFTKMAAEQKVKK*" gene complement(3450649..3451287) /gene="hisH" /locus_tag="BSU_34890" /old_locus_tag="BSU34890" promotor_no_box 3451145..3451245 /Source="Nicolas_upshift_promotors" /id="U2736" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.973026973026973" /psig="0.000999000999001" /xcortree=24 /SigmaFactorBS="gaaccgactcccggcaaaatgaaagcatcagcttctttcagc tcctccggcttttcagaaacaaaatacggcacgccgacacgttcaagcgcctttgaga c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_no_box" upshifts 3451205 /Source="Nicolas_upshifts" /id="U2736" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.973026973026973" /psig="0.000999000999001" /xcortree=24 /SigmaFactorBS="gaaccgactcccggcaaaatgaaagcatcagcttctttcagc tcctccggcttttcagaaacaaaatacggcacgccgacacgttcaagcgcctttgaga c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" CDS complement(3451288..3451872) /gene="hisB" /locus_tag="BSU_34900" /old_locus_tag="BSU34900" /EC_number="4.2.1.19" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 1400209, 24311587; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="imidazoleglycerol-phosphate dehydratase [Mn(II)-dependent]" /protein_id="NP_391370.1" /db_xref="EnsemblGenomes-Gn:BSU34900" /db_xref="EnsemblGenomes-Tr:CAB15495" /db_xref="GOA:O34683" /db_xref="InterPro:IPR000807" /db_xref="InterPro:IPR020565" /db_xref="InterPro:IPR020568" /db_xref="SubtiList:BG12598" /db_xref="UniProtKB/Swiss-Prot:O34683" /translation="MRKAERVRKTNETDIELAFTIDGGGQADIKTDVPFMTHMLDLFT KHGQFDLSINAKGDVDIDDHHTTEDIGICLGQALLEALGDKKGIKRYGSAFVPMDEAL AQVVIDLSNRPHLEMRADFPAAKVGTFDTELVHEFLWKLALEARMNLHVIVHYGTNTH HMIEAVFKALGRALDEATTIDPRVKGIPSTKGML*" gene complement(3451288..3451872) /gene="hisB" /locus_tag="BSU_34900" /old_locus_tag="BSU34900" CDS complement(3451869..3453152) /gene="hisD" /locus_tag="BSU_34910" /old_locus_tag="BSU34910" /EC_number="1.1.1.23" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 10353847, 10353848, 21672513, 24140957; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="histidinol dehydrogenase" /protein_id="NP_391371.1" /db_xref="EnsemblGenomes-Gn:BSU34910" /db_xref="EnsemblGenomes-Tr:CAB15496" /db_xref="GOA:O34651" /db_xref="InterPro:IPR001692" /db_xref="InterPro:IPR012131" /db_xref="InterPro:IPR016161" /db_xref="InterPro:IPR022695" /db_xref="SubtiList:BG12599" /db_xref="UniProtKB/Swiss-Prot:O34651" /translation="MKIKTISGAERLSLKRSIDAGTEEQRKTVRSIIEDVKANGDQAV RSYTAKFDCIEIDSPLVTKEEFEEAYTSLDSRLLQVIRQAIENIREYHERQLQSSWFY HRKDGTMLGQKVTALDSAGVYVPGGTAAYPSSVLMNVIPALVAGVERIVLVTPPGKDG LLSPGVLVAAAELGIKDIYKMGGAQAIAALAYGTETIEPVDKITGPGNIYVALAKREV FGDVDIDMIAGPSEIVVLADETAIPSEIAADLLSQAEHDKLSSCVFVTDSMALAETVS AEVNKQLETLPRREIAEASVRDYGCIYVAETMVEAIETVNTLAPEHLEIITQSPEALL GSIKHAGAIFLGRYSPEPVGDYFAGPNHVLPTNGTARFSSPLNVTDFQKKSSIISYSQ SAFEEHAESIAAFARLEGLEAHARSIEARERRISK*" gene complement(3451869..3453152) /gene="hisD" /locus_tag="BSU_34910" /old_locus_tag="BSU34910" CDS complement(3453149..3453790) /gene="hisG" /locus_tag="BSU_34920" /old_locus_tag="BSU34920" /EC_number="2.4.2.17" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 10430882, 12269828, 12511575, 14741209, 15660995, 17154531, 21774583, 22989207, 28092443, 28872824; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="ATP phosphoribosyltransferase" /protein_id="NP_391372.1" /db_xref="EnsemblGenomes-Gn:BSU34920" /db_xref="EnsemblGenomes-Tr:CAB15497" /db_xref="GOA:O34520" /db_xref="InterPro:IPR001348" /db_xref="InterPro:IPR013820" /db_xref="InterPro:IPR018198" /db_xref="InterPro:IPR024893" /db_xref="PDB:2VD2" /db_xref="SubtiList:BG12601" /db_xref="UniProtKB/Swiss-Prot:O34520" /translation="MGKLLTMAMPKGRIFEEAAGLLRQAGYRLPEEFEDSRKLIIDVP EENLRFILAKPMDVTTYVEHGVADVGIAGKDVMLEEERDVYEVLDLNISKCHLAVAGL PNTDWSGVAPRIATKYPNVASSYFREQGEQVEIIKLNGSIELAPLIGLADRIVDIVST GQTLKENGLVETEHICDITSRFIVNPVSYRMKDDVIDEMASRLSLVVEGETAK*" gene complement(3453149..3453790) /gene="hisG" /locus_tag="BSU_34920" /old_locus_tag="BSU34920" CDS complement(3453783..3454958) /gene="hisZ" /locus_tag="BSU_34930" /old_locus_tag="BSU34930" /EC_number="2.4.2.17" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 10430882, 12269828, 12511575, 15660995; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="histidyl-tRNA synthetase-like subunit of ATP phophoribosyltransferase" /protein_id="NP_391373.1" /db_xref="EnsemblGenomes-Gn:BSU34930" /db_xref="EnsemblGenomes-Tr:CAB15498" /db_xref="GOA:O34459" /db_xref="InterPro:IPR004516" /db_xref="InterPro:IPR004517" /db_xref="InterPro:IPR006195" /db_xref="SubtiList:BG12606" /db_xref="UniProtKB/Swiss-Prot:O34459" /translation="MFMFEKPHGMRDTLPGLYETKKKVRRSLTDLIDKWGYQFMETPT LEFYDTVGVQSAIEEQQLFKLLDQDGKTLVLRPDMTGPIARVAASKLLKHGHPLRVGY AANVFRAQEREGGRPAEFEQVGVELIGDGTTSADAEVIALVVGALKNAGLASFKIAIG HAGIADALFVEVLGNVERADVLRRFLYEKNYVGYREHVKSLPLSSIDKSRLLELLELR GGIEVCGRAEEIVDSAQGKSVVDELKALWDILEDYGCTENVRLDLNMVSHMSYYTGIL FEVYAENVGFVIGSGGRYNKLLGHFDSPAPATGFGLRIDRLIEALHMKDEPCEIDAVI FSKEQRAQAIAYANEERMKGNKVVLQDLSGIENIDQMTKSFANVTYFIGARKEEQNG* " gene complement(3453783..3454958) /gene="hisZ" /locus_tag="BSU_34930" /old_locus_tag="BSU34930" S_feature complement(3454959..3455036) /Source="Nicolas_S_feature" /locus_tag="new_3589361_3589438_c" /HighExp="Diami, M/G, Etha, BMM, MG 15, MG 10, T-1.10H, T-0.40H, T-1.40H, Cold" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1332" promotor_-35 3455002..3455008 /Source="Nicolas_upshift_promotors" /id="U2737" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.956043956043956" /psig="0.995004995004995" /xcortree=2775 /SigmaFactorBS="ccgctgttatcttatgaaggaaaattccgAATCCTTtagttc gctaaTATGATAATATGTTAGCAGAtgaaagaatgaaaatcaacgcttaacttcagta a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3455020..3455039 /Source="Nicolas_upshift_promotors" /id="U2737" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.956043956043956" /psig="0.995004995004995" /xcortree=2775 /SigmaFactorBS="ccgctgttatcttatgaaggaaaattccgAATCCTTtagttc gctaaTATGATAATATGTTAGCAGAtgaaagaatgaaaatcaacgcttaacttcagta a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-10 complement(3455020..3455039) /Source="Nicolas_upshift_promotors" /id="U2738" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.486513486513487" /psig=1 /xcortree=2777 /SigmaFactorBS="ggatatttgaactaaaaatatccttactgaagttaagCGTTG ATTttcattctttcaTCTGCTAACATATTATCATAttagcgaactaaaggattcggaa t" /listShort="S1332, hisZ, hisG, hisD, hisB, hisH, hisA, hisF, hisI, S1331, S1330, yvcA, yvcB, yvzA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3455033 /Source="Nicolas_upshifts" /id="U2737" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.956043956043956" /psig="0.995004995004995" /xcortree=2775 /SigmaFactorBS="ccgctgttatcttatgaaggaaaattccgAATCCTTtagttc gctaaTATGATAATATGTTAGCAGAtgaaagaatgaaaatcaacgcttaacttcagta a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" upshifts complement(3455036) /Source="Nicolas_upshifts" /id="U2738" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.486513486513487" /psig=1 /xcortree=2777 /SigmaFactorBS="ggatatttgaactaaaaatatccttactgaagttaagCGTTG ATTttcattctttcaTCTGCTAACATATTATCATAttagcgaactaaaggattcggaa t" /listShort="S1332, hisZ, hisG, hisD, hisB, hisH, hisA, hisF, hisI, S1331, S1330, yvcA, yvcB, yvzA" /GFF_Attribute="listLong" promotor_-35 complement(3455052..3455059) /Source="Nicolas_upshift_promotors" /id="U2738" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.486513486513487" /psig=1 /xcortree=2777 /SigmaFactorBS="ggatatttgaactaaaaatatccttactgaagttaagCGTTG ATTttcattctttcaTCTGCTAACATATTATCATAttagcgaactaaaggattcggaa t" /listShort="S1332, hisZ, hisG, hisD, hisB, hisH, hisA, hisF, hisI, S1331, S1330, yvcA, yvcB, yvzA" /GFF_Attribute="listLong" /label="promotor_-35" misc_feature 3455168..3455187 /Source="Nicolas_upshift_promotors" /id="U2739" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.999000999001" /psig=1 /xcortree=2160 /SigmaFactorBS="aatcatgaataatgtattaaaggtacgtaatatctcaaattc tttatgtttggCATGCTATAATACAAATCAAatagagaacaaggagataaagatgaaa a" /listShort="yvpB, S1333, pelC" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 3455175 /Source="Nicolas_upshifts" /id="U2739" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.999000999001" /psig=1 /xcortree=2160 /SigmaFactorBS="aatcatgaataatgtattaaaggtacgtaatatctcaaattc tttatgtttggCATGCTATAATACAAATCAAatagagaacaaggagataaagatgaaa a" /listShort="yvpB, S1333, pelC" /GFF_Attribute="listLong" CDS 3455209..3455961 /gene="yvpB" /locus_tag="BSU_34940" /old_locus_tag="BSU34940" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative hydratase" /protein_id="NP_391374.1" /db_xref="EnsemblGenomes-Gn:BSU34940" /db_xref="EnsemblGenomes-Tr:CAB15499" /db_xref="InterPro:IPR016997" /db_xref="SubtiList:BG14130" /db_xref="UniProtKB/Swiss-Prot:O34735" /translation="MKTLRTLCVLMILSGVIFFGLKIDAKDIDIPFLNSLKKVVSDSD TDSAANSKKELKGSAKPLDVILYNQMDAPRLYNGCEVTSLAMVLNYAGYDVTKNTLAN QVATVPLTYSSGLKGDPNDGFVGDMANGPGLGVYHRPIYQLAKTYAGDKVSDLTGKSI SAVYQQLEKGNPVWVITTANFTPVDNMQTWKTPNGTIEITYSEHSVAVTGYDDKYVYL NDPYGYKNRKTDRTSFEKAWKQMGSQAVVIQK*" gene 3455209..3455961 /gene="yvpB" /locus_tag="BSU_34940" /old_locus_tag="BSU34940" S_feature 3455962..3456200 /Source="Nicolas_S_feature" /locus_tag="new_3590364_3590602" /HighExp="LBGstat, LPhT, Cold, Sw, M/G, G180, G135, LBGtran, G150, M40t45" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1333" promotor_-10 complement(3455983..3455994) /Source="Nicolas_upshift_promotors" /id="U2740" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=820 /SigmaFactorBS="ggaaaatgaatcgatcttaccgattgatacaaaaAGCATGAa tattgtcgtatttGCTCAGAATAGAgcatagtgaggcttcaggtgtttacttttgaat a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3455989) /Source="Nicolas_upshifts" /id="U2740" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=820 /SigmaFactorBS="ggaaaatgaatcgatcttaccgattgatacaaaaAGCATGAa tattgtcgtatttGCTCAGAATAGAgcatagtgaggcttcaggtgtttacttttgaat a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(3456009..3456015) /Source="Nicolas_upshift_promotors" /id="U2740" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=820 /SigmaFactorBS="ggaaaatgaatcgatcttaccgattgatacaaaaAGCATGAa tattgtcgtatttGCTCAGAATAGAgcatagtgaggcttcaggtgtttacttttgaat a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" CDS 3456201..3456866 /gene="pelC" /locus_tag="BSU_34950" /old_locus_tag="BSU34950" /EC_number="4.2.2.2" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:10658655, 15187182, 16514142, 20000851, 24236123" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10658655, 15187182, 16514142, 20000851, 24236123; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="secreted pectate (polygalacturonate) lyase" /protein_id="NP_391375.1" /db_xref="EnsemblGenomes-Gn:BSU34950" /db_xref="EnsemblGenomes-Tr:CAB15500" /db_xref="GOA:O34310" /db_xref="InterPro:IPR004898" /db_xref="InterPro:IPR011050" /db_xref="InterPro:IPR012334" /db_xref="SubtiList:BG14129" /db_xref="UniProtKB/Swiss-Prot:O34310" /translation="MKKIVSILFMFGLVMGFSQFQPSTVFAADKVVHETIIVPKNTTY DGKGQRFVAGKELGDGSQSENQDPVFRVEDGATLKNVVLGAPAADGVHTYGNVNIQNV KWEDVGEDALTVKKEGKVTIDGGSAQKASDKIFQINKASTFTVKNFTADNGGKFIRQL GGSTFHVDVIIDKCTITNMKEAIFRTDSKTSTVRMTNTRYSNVGQKWIGVQHIYENNN TQF*" gene 3456201..3456866 /gene="pelC" /locus_tag="BSU_34950" /old_locus_tag="BSU34950" downshifts 3456837 /Source="Nicolas_upshifts" /id="D1809" /incds=0 /nref=85 /ntot=213 /MaxReadThrough="1.40389" /MaxDrop="4.93342" /score="16.0973385" /energy="-14.9" /TU="NA" /idTUdmin="U2739" /TUdmin=176 /isTUend="FALSE" CDS complement(3456886..3457404) /gene="hprF" /locus_tag="BSU_34960" /old_locus_tag="BSU34960" /EC_number="2.3.1.-" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:21761520, 27226549" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 21761520, 27226549; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="dephosphorylated heptaprenylglyceryl phosphate O-acetyltransferase" /protein_id="NP_391376.1" /db_xref="EnsemblGenomes-Gn:BSU34960" /db_xref="EnsemblGenomes-Tr:CAB15501" /db_xref="GOA:O34993" /db_xref="InterPro:IPR001451" /db_xref="InterPro:IPR011004" /db_xref="SubtiList:BG14128" /db_xref="UniProtKB/Swiss-Prot:O34993" /translation="MRKTDRHPVSGANSLWHVYQTVPFLKVVKNFIVIQIARYTPFIG MKNWLYRTFLRMKVGKQTSFALMVMPDIMFPEKISVGTNTIIGYNTTILAHEYLIHEY RIGKVLIGDEVMIGANTTILPGVKIGDGAVVSAGTLVHKDVPDGAFVGGNPMRIIYTK EEMQERLKKSAE*" gene complement(3456886..3457404) /gene="hprF" /locus_tag="BSU_34960" /old_locus_tag="BSU34960" downshifts complement(3456920) /Source="Nicolas_upshifts" /id="D1810" /incds=0 /nref=245 /ntot=283 /MaxReadThrough="1.27998" /MaxDrop="6.44997" /score="38.2106579" /energy="-14.9" /TU="NA" /idTUdmin="U2741" /TUdmin="-7" /isTUend="TRUE" CDS complement(3457408..3458058) /gene="ppaX" /locus_tag="BSU_34970" /old_locus_tag="BSU34970" /EC_number="3.6.1.1" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:9465101, 12359880, 12411438, 16182622, 22353596" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9465101, 12359880, 12411438, 16182622, 22353596; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="Hpr-associated pyrophosphatase" /protein_id="NP_391377.1" /db_xref="EnsemblGenomes-Gn:BSU34970" /db_xref="EnsemblGenomes-Tr:CAB15502" /db_xref="GOA:Q9JMQ2" /db_xref="InterPro:IPR006439" /db_xref="InterPro:IPR023198" /db_xref="InterPro:IPR023214" /db_xref="InterPro:IPR023733" /db_xref="InterPro:IPR036412" /db_xref="SubtiList:BG14127" /db_xref="UniProtKB/Swiss-Prot:Q9JMQ2" /translation="MSDKQVTTILFDLDGTLINTNELIIASFLHTLEHYYPSKYKRED VLAFIGPSLFDTFSSMDPDKCEDMIAMYRAYNHDMHDSLVTEYETVYETLDALKKAGF TLGIVTTKLRDTVNMGLKLTGIGEFFETVVTLDDVTNAKPDPEPVLLALKQLGSEPAE AIMVGDNYHDVLAGKNAGTKTAGVAWTIKGPEMLAKHEPDFMLEKMSDLLQIVGVK*" gene complement(3457408..3458058) /gene="ppaX" /locus_tag="BSU_34970" /old_locus_tag="BSU34970" CDS complement(3458055..3458993) /gene="yvoD" /locus_tag="BSU_34980" /old_locus_tag="BSU34980" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406, 27226549; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative integral inner membrane protein with nucleotide binding domain" /protein_id="NP_391378.1" /db_xref="EnsemblGenomes-Gn:BSU34980" /db_xref="EnsemblGenomes-Tr:CAB15503" /db_xref="GOA:O34382" /db_xref="InterPro:IPR011642" /db_xref="SubtiList:BG14126" /db_xref="UniProtKB/Swiss-Prot:O34382" /translation="MKKIFLAGLAAGFQTTWTLGKVIFPVTLLVTLLQHTPVMDWLVR LITPVMGLFGLSGEAAIPLVLGNMLNLYAGIAGILTLDLSVKEVFILAVMLSFCHNLI IESTVAAKVGIRIGVILAVRIGLAAVSAIVINLIWHGGKETAQYGFIAAKSAAPDSWL GMLAEALTKAGLGVLQLAAIVIPLMIIIQFLRDLGWLYRFSRWLSPFTQLLGMNKNTS MTMVTGLTIGLAYGAGVMIKAVEDDGVSKRDMTLAFIFLVACHAVVEDTLVFIPLGIP VWPLLLIRVTTAVLLTMAIAHTWKKWKPSAVGKEAI*" gene complement(3458055..3458993) /gene="yvoD" /locus_tag="BSU_34980" /old_locus_tag="BSU34980" CDS complement(3459017..3459826) /gene="lgt" /locus_tag="BSU_34990" /old_locus_tag="BSU34990" /EC_number="2.4.99.-" /function="16.5: Explore" /function="16.13: Shape" /function="16.6: Maintain" /function="16.2: Construct biomass (Anabolism)" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:10096076, 11425480, 15126458, 15849754, 16850406, 18556788, 27226549" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10096076, 11425480, 15126458, 15849754, 16850406, 18556788, 27226549; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="prelipoprotein diacylglycerol transferase" /protein_id="NP_391379.1" /db_xref="EnsemblGenomes-Gn:BSU34990" /db_xref="EnsemblGenomes-Tr:CAB15504" /db_xref="GOA:O34752" /db_xref="InterPro:IPR001640" /db_xref="SubtiList:BG12611" /db_xref="UniProtKB/Swiss-Prot:O34752" /translation="MNEAIEPLNPIAFQLGPLAVHWYGIIIGLGALLGLWIAMRESEK RGLQKDTFIDLVLFAIPIAIICARIYYVAFEWDYYAAHPGEIIKIWKGGIAIHGGLIG AILTGYVFSRVKNLSFWKLADIAAPSILLGQAIGRWGNFMNQEAHGEAVSRAFLENLH LPEFIINQMYINGQYYHPTFLYESLWSFVGVIVLLLLRRANLRRGEMFLIYIIWYSIG RYFIEGMRTDSLMLTDSLRIAQVISIVLIVLAVAAIIFRRVKGYSKERYAE*" gene complement(3459017..3459826) /gene="lgt" /locus_tag="BSU_34990" /old_locus_tag="BSU34990" CDS complement(3459840..3460772) /gene="hprK" /locus_tag="BSU_35000" /old_locus_tag="BSU35000" /EC_number="2.7.4.-" /EC_number="2.7.11.-" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:10636874, 12009882, 12359875, 12411438, 12779331, 15023355, 16267306, 17878158, 20487301, 21992469, 27226549" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10636874, 12009882, 12359875, 12411438, 12779331, 15023355, 16267306, 17878158, 20487301, 21992469, 27226549; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="serine/threonine protein kinase/phosphorylase (pyrophosphate-producing)" /protein_id="NP_391380.1" /db_xref="EnsemblGenomes-Gn:BSU35000" /db_xref="EnsemblGenomes-Tr:CAB15505" /db_xref="GOA:O34483" /db_xref="InterPro:IPR003755" /db_xref="InterPro:IPR011104" /db_xref="InterPro:IPR011126" /db_xref="InterPro:IPR028979" /db_xref="SubtiList:BG14125" /db_xref="UniProtKB/Swiss-Prot:O34483" /translation="MAKVRTKDVMEQFNLELISGEEGINRPITMSDLSRPGIEIAGYF TYYPRERVQLLGKTELSFFEQLPEEEKKQRMDSLCTDVTPAIILSRDMPIPQELIDAS EKNGVPVLRSPLKTTRLSSRLTNFLESRLAPTTAIHGVLVDIYGVGVLITGKSGVGKS ETALELVKRGHRLVADDCVEIRQEDQDTLVGNAPELIEHLLEIRGLGIINVMTLFGAG AVRSNKRITIVMNLELWEQGKQYDRLGLEEETMKIIDTEITKLTIPVRPGRNLAVIIE VAAMNFRLKRMGLNAAEQFTNKLADVIEDGEQEE*" gene complement(3459840..3460772) /gene="hprK" /locus_tag="BSU_35000" /old_locus_tag="BSU35000" promotor_-10 complement(3460814..3460833) /Source="Nicolas_upshift_promotors" /id="U2741" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.518481518481518" /psig="0.998001998001998" /xcortree=2677 /SigmaFactorBS="ggtgttttccccccttttataaaatcTGTTTTaggttcaagc ccgaaAGTGATAAAATGAAAGTATTgtgagcaagctcggggcagcccggaacaggagg a" /listShort="hprK, lgt, yvoD, ppaX, yvoF" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3460820) /Source="Nicolas_upshifts" /id="U2741" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.518481518481518" /psig="0.998001998001998" /xcortree=2677 /SigmaFactorBS="ggtgttttccccccttttataaaatcTGTTTTaggttcaagc ccgaaAGTGATAAAATGAAAGTATTgtgagcaagctcggggcagcccggaacaggagg a" /listShort="hprK, lgt, yvoD, ppaX, yvoF" /GFF_Attribute="listLong" promotor_-35 complement(3460849..3460854) /Source="Nicolas_upshift_promotors" /id="U2741" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.518481518481518" /psig="0.998001998001998" /xcortree=2677 /SigmaFactorBS="ggtgttttccccccttttataaaatcTGTTTTaggttcaagc ccgaaAGTGATAAAATGAAAGTATTgtgagcaagctcggggcagcccggaacaggagg a" /listShort="hprK, lgt, yvoD, ppaX, yvoF" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 3460889..3460896 /Source="Nicolas_upshift_promotors" /id="U2742" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.664335664335664" /psig="0.997002997002997" /xcortree=2396 /SigmaFactorBS="taaaacagattttataaaaggggggaaaacacctcagctggT CTAGATCactagtctgaaaaaGAGTAAAATAAAGGTATTcaaattccagaaaggcgga t" /listShort="nagA, nagBA, yvoA" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 3460908 /Source="Nicolas_upshifts" /id="U2742" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.664335664335664" /psig="0.997002997002997" /xcortree=2396 /SigmaFactorBS="taaaacagattttataaaaggggggaaaacacctcagctggT CTAGATCactagtctgaaaaaGAGTAAAATAAAGGTATTcaaattccagaaaggcgga t" /listShort="nagA, nagBA, yvoA" /GFF_Attribute="listLong" promotor_-10 3460911..3460928 /Source="Nicolas_upshift_promotors" /id="U2742" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.664335664335664" /psig="0.997002997002997" /xcortree=2396 /SigmaFactorBS="taaaacagattttataaaaggggggaaaacacctcagctggT CTAGATCactagtctgaaaaaGAGTAAAATAAAGGTATTcaaattccagaaaggcgga t" /listShort="nagA, nagBA, yvoA" /GFF_Attribute="listLong" /label="promotor_-10" CDS 3460954..3462144 /gene="nagA" /locus_tag="BSU_35010" /old_locus_tag="BSU35010" /EC_number="3.5.1.25" /function="16.2: Construct biomass (Anabolism)" /function="16.13: Shape" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:6774970, 14557261, 21602348" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 6774970, 14557261, 21602348; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="N-acetylglucosamine-6-phosphate deacetylase" /protein_id="NP_391381.1" /db_xref="EnsemblGenomes-Gn:BSU35010" /db_xref="EnsemblGenomes-Tr:CAB15506" /db_xref="GOA:O34450" /db_xref="InterPro:IPR003764" /db_xref="InterPro:IPR006680" /db_xref="InterPro:IPR011059" /db_xref="InterPro:IPR032466" /db_xref="PDB:2VHL" /db_xref="SubtiList:BG12630" /db_xref="UniProtKB/Swiss-Prot:O34450" /translation="MAESLLIKDIAIVTENEVIKNGYVGINDGKISTVSTERPKEPYS KEIQAPADSVLLPGMIDIHIHGGYGADTMDASFSTLDIMSSRLPEEGTTSFLATTITQ EHGNISQALVNAREWKAAEESSLLGAELLGIHLEGPFVSPKRAGAQPKEWIRPSDVEL FKKWQQEAGGLIKIVTLAPEEDQHFELIRHLKDESIIASMGHTDADSALLSDAAKAGA SHMTHLYNAMSPFHHREPGVIGTALAHDGFVTELIADGIHSHPLAAKLAFLAKGSSKL ILITDSMRAKGLKDGVYEFGGQSVTVRGRTALLSDGTLAGSILKMNEGARHMREFTNC SWTDIANITSENAAKQLGIFDRKGSVTVGKDADLVIVSSDCEVILTICRGNIAFISKE ADQI*" gene 3460954..3462144 /gene="nagA" /locus_tag="BSU_35010" /old_locus_tag="BSU35010" promotor_-35 3461942..3461948 /Source="Nicolas_upshift_promotors" /id="U2743" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=172 /SigmaFactorBS="cgatcctcaaaatgaacgaaggcgcacggcatatgcgtgAGT TTACaaattgctcttggacGGATATAGCTAATATAACTtctgaaaacgcggccaaaca g" /listShort="nagBA, yvoA" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 3461963 /Source="Nicolas_upshifts" /id="U2743" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=172 /SigmaFactorBS="cgatcctcaaaatgaacgaaggcgcacggcatatgcgtgAGT TTACaaattgctcttggacGGATATAGCTAATATAACTtctgaaaacgcggccaaaca g" /listShort="nagBA, yvoA" /GFF_Attribute="listLong" promotor_-10 3461964..3461982 /Source="Nicolas_upshift_promotors" /id="U2743" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=172 /SigmaFactorBS="cgatcctcaaaatgaacgaaggcgcacggcatatgcgtgAGT TTACaaattgctcttggacGGATATAGCTAATATAACTtctgaaaacgcggccaaaca g" /listShort="nagBA, yvoA" /GFF_Attribute="listLong" /label="promotor_-10" CDS 3462141..3462869 /gene="nagBA" /locus_tag="BSU_35020" /old_locus_tag="BSU35020" /EC_number="3.5.99.6" /function="16.2: Construct biomass (Anabolism)" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:15755726, 18436239" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15755726, 18436239; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="glucosamine-6-phosphate isomerase" /protein_id="NP_391382.1" /db_xref="EnsemblGenomes-Gn:BSU35020" /db_xref="EnsemblGenomes-Tr:CAB15507" /db_xref="GOA:O35000" /db_xref="InterPro:IPR004547" /db_xref="InterPro:IPR006148" /db_xref="InterPro:IPR018321" /db_xref="PDB:2BKV" /db_xref="PDB:2BKX" /db_xref="SubtiList:BG12631" /db_xref="UniProtKB/Swiss-Prot:O35000" /translation="MKVMECQTYEELSQIAARITADTIKEKPDAVLGLATGGTPEGTY RQLIRLHQTENLSFQNITTVNLDEYAGLSSDDPNSYHFYMNDRFFQHIDSKPSRHFIP NGNADDLEAECRRYEQLVDSLGDTDIQLLGIGRNGHIGFNEPGTSFKSRTHVVTLNEQ TRQANARYFPSIDSVPKKALTMGIQTILSSKRILLLISGKSKAEAVRKLLEGNISEDF PASALHLHSDVTVLIDREAASLRP*" gene 3462141..3462869 /gene="nagBA" /locus_tag="BSU_35020" /old_locus_tag="BSU35020" CDS 3462887..3463618 /gene="nagR" /locus_tag="BSU_35030" /old_locus_tag="BSU35030" /experiment="publication(s) with functional evidences, PMID:16207374, 20047956, 21602348, 23667565, 24673833, 26162881" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16207374, 20047956, 21602348, 23667565, 24673833, 26162881; Product type r : regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator (GntR family)" /protein_id="NP_391383.1" /db_xref="EnsemblGenomes-Gn:BSU35030" /db_xref="EnsemblGenomes-Tr:CAB15508" /db_xref="GOA:O34817" /db_xref="InterPro:IPR000524" /db_xref="InterPro:IPR011663" /db_xref="InterPro:IPR028978" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="PDB:2WV0" /db_xref="PDB:4U0V" /db_xref="PDB:4U0W" /db_xref="PDB:4U0Y" /db_xref="PDB:4WWC" /db_xref="SubtiList:BG14124" /db_xref="UniProtKB/Swiss-Prot:O34817" /translation="MNINKQSPIPIYYQIMEQLKTQIKNGELQPDMPLPSEREYAEQF GISRMTVRQALSNLVNEGLLYRLKGRGTFVSKPKMEQALQGLTSFTEDMKSRGMTPGS RLIDYQLIDSTEELAAILGCGHPSSIHKITRVRLANDIPMAIESSHIPFELAGELNES HFQSSIYDHIERYNSIPISRAKQELEPSAATTEEANILGIQKGAPVLLIKRTTYLQNG TAFEHAKSVYRGDRYTFVHYMDRLS*" gene 3462887..3463618 /gene="nagR" /locus_tag="BSU_35030" /old_locus_tag="BSU35030" CDS complement(3463638..3467507) /gene="yvnB" /locus_tag="BSU_35040" /old_locus_tag="BSU35040" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 27542896; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative exported hydrolase" /protein_id="NP_391384.1" /db_xref="EnsemblGenomes-Gn:BSU35040" /db_xref="EnsemblGenomes-Tr:CAB15509" /db_xref="GOA:O34986" /db_xref="InterPro:IPR004843" /db_xref="InterPro:IPR011401" /db_xref="InterPro:IPR013783" /db_xref="InterPro:IPR029052" /db_xref="InterPro:IPR036415" /db_xref="SubtiList:BG14123" /db_xref="UniProtKB/Swiss-Prot:O34986" /translation="MRKYTVIASILLSFLSVLSGGHHESKAFPVVQQELFQTPHYIPL LENPPQIDVKAEMRSNLMIEAQVRDNSYQAFSAFLFYKQSNELGYKMVPMDPTPGAVR KFLAQIPKRLIWNSELEYYIVMSNGKQRVESETKKLKLEGYQADLAHIPELLITELAV DTKNIGRADGYEFIEIFNTTDRTIDFKDYHIRYRYPKEGPDSDLIWRPDERILIPSGE TFVVWLKPAGHPELTSADFNRYYQTQLKEGKNLAVIDETEGMANTRPRAVVISTNTGK DISVAHYRKHALRRLSSVLYKYPLNGTAELLNISIGEKNPSPGTVLQAQVPDQKRKIK LDKEKPVIEDLTDRKPVRPAESIELRADIRDRSLVKTVAFYYRTDENKPFKRILAEKD RNDNLFHYIVYSPELIGKDQLEYYVAAGDGINEARTPVKMIDIKQTSKAHGLRMNIEN RDTLSGTQFLKATTEGRADSIKLWIDGKKQVTEPAMEKEVYFAFDTRKTNLYFKNAVT MEGKVLKVFDDTTNKYRTYSVPLPETLLRKGKQLQRITIRSGSKVSPFDTAENRDDFL VKNARLVLSDGTVIRDQRVSPEKELFIGDNQRSNKSWQFQFNLPDGLFTSQLLEWDTS KLSEGAHHIQASDGKENVSLVVRVDNSGPHIEPNITEGQTYKGNLILQADMYDKWSRI EEAEASLDGESITLPYHTSSSDLLPGKHSLKVTATDLAGNKTVIERIFKTEREHPDQP EVIDSEADTHKAKLSVRVKDPTNDAMDVGFYRGFQYTARNHVKIFKHASLTEPPKSFV PERETPFTNKELERVSAADGKTVSTENKELFPYHRFEVTVDPSIDENDLAESVWKGSS LPGRKVTMYAWNYRTNEWQPVDSFVAKDDKPFTLKASVIAADFVRESKMNVIVQDEIP PAKDMYTFVWMSDTQYYAESYPHIFDKQTEWIKDNQKQLNIKYVFHTGDIVDDSADIR QWKNADRSMSVLDKSGIPYGVLAGNHDVGHKDGSYRAFGKYFGSDRFDKKFHYGGSYK NNRGHYDLISSNGNDYIMLYMGWGITDEDIAWMNQVLKKHPDRMAILAFHEYLLVSGN RSPIGEKIFKEIVKPNPNVVMVLSGHYHSAMRKTDELDDDGDGKPDRLVHQMLADYQG GPEGGQGYLRLLQFDQANDMVHVSTYSPYVKDKNYYDTDTYGNKDEFSLSLDLKPRIK KVETDYFECNVYTNEELGKREQVKSGDTAEFRWDHLEPQSVYYWYIIVEDSFNGKTKS PIWKFKTKKETYRPAPDQFDFRHVSNP*" gene complement(3463638..3467507) /gene="yvnB" /locus_tag="BSU_35040" /old_locus_tag="BSU35040" downshifts complement(3463760) /Source="Nicolas_upshifts" /id="D1811" /incds=1 /nref=19 /ntot=109 /MaxReadThrough="1.28942" /MaxDrop="4.39575" /score="28.0438848" /energy="-16.5" /TU="NA" /idTUdmin="U2744" /TUdmin="-5" /isTUend="TRUE" promotor_-10 complement(3467527..3467538) /Source="Nicolas_upshift_promotors" /id="U2744" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=878 /SigmaFactorBS="cagacgtttttttgttctttatgcacaaaaatgaaCTCATAA gcttccctgttcagACGCAAAATACAtgaaaagggaggtgctttgatgaggaaataca c" /listShort="yvnB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3467534) /Source="Nicolas_upshifts" /id="U2744" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=878 /SigmaFactorBS="cagacgtttttttgttctttatgcacaaaaatgaaCTCATAA gcttccctgttcagACGCAAAATACAtgaaaagggaggtgctttgatgaggaaataca c" /listShort="yvnB" /GFF_Attribute="listLong" promotor_-35 complement(3467553..3467559) /Source="Nicolas_upshift_promotors" /id="U2744" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=878 /SigmaFactorBS="cagacgtttttttgttctttatgcacaaaaatgaaCTCATAA gcttccctgttcagACGCAAAATACAtgaaaagggaggtgctttgatgaggaaataca c" /listShort="yvnB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 3467597..3467603 /Source="Nicolas_upshift_promotors" /id="U2745" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.473526473526474" /psig=1 /xcortree=2922 /SigmaFactorBS="catttttgtgcataaagaacaaaaaaacgtctgtcTCTTGAA aattccactattaCCCAGTAAACTAAGGATAGTtaaccagttaacaattaaatcagag a" /listShort="yvnA, S1334, S1335" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3467617..3467636 /Source="Nicolas_upshift_promotors" /id="U2745" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.473526473526474" /psig=1 /xcortree=2922 /SigmaFactorBS="catttttgtgcataaagaacaaaaaaacgtctgtcTCTTGAA aattccactattaCCCAGTAAACTAAGGATAGTtaaccagttaacaattaaatcagag a" /listShort="yvnA, S1334, S1335" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3467622 /Source="Nicolas_upshifts" /id="U2745" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.473526473526474" /psig=1 /xcortree=2922 /SigmaFactorBS="catttttgtgcataaagaacaaaaaaacgtctgtcTCTTGAA aattccactattaCCCAGTAAACTAAGGATAGTtaaccagttaacaattaaatcagag a" /listShort="yvnA, S1334, S1335" /GFF_Attribute="listLong" CDS 3467672..3468145 /gene="yvnA" /locus_tag="BSU_35050" /old_locus_tag="BSU35050" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative transcriptional regulator" /protein_id="NP_391385.1" /db_xref="EnsemblGenomes-Gn:BSU35050" /db_xref="EnsemblGenomes-Tr:CAB15510" /db_xref="GOA:O34692" /db_xref="InterPro:IPR000835" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG14122" /db_xref="UniProtKB/Swiss-Prot:O34692" /translation="MDNSIHDELFQAIQQFALKRDKRVWQKVQIPSIGISSQHHDHLK KDWTLTQLHIVSCIHTSQNVNNSFLASRLHISKAAVSKAVHALLKHNIITVTKKPGNK KEIFYTLTDSGRKLAALHEQLHEKAKEQYKQLFNEFSIDDLKTVTAFFNLWIKYM*" gene 3467672..3468145 /gene="yvnA" /locus_tag="BSU_35050" /old_locus_tag="BSU35050" S_feature 3468146..3468253 /Source="Nicolas_S_feature" /locus_tag="new_3602548_3602655" /HighExp="T5.0H, T4.0H, T3.30H, T3.0H, T2.30H, M9-stat, T2.0H, T1.30H, T1.0H, BC" /AntisenseName="cypX" /AntisenseCor="-1.1473096183385199E-3" /AntisenseRegPval=0 /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1334" CDS complement(3468186..3469403) /gene="cypX" /locus_tag="BSU_35060" /old_locus_tag="BSU35060" /EC_number="1.14.-.-" /function="16.5: Explore" /function="16.14: Store" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:4204912, 20690619, 27542896" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 4204912, 20690619, 27542896; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="cyclo-L-leucyl-L-leucyl dipeptide oxidase, pulcheriminic synthase" /protein_id="NP_391386.1" /db_xref="EnsemblGenomes-Gn:BSU35060" /db_xref="EnsemblGenomes-Tr:CAB15511" /db_xref="GOA:O34926" /db_xref="InterPro:IPR001128" /db_xref="InterPro:IPR002397" /db_xref="InterPro:IPR017972" /db_xref="InterPro:IPR030904" /db_xref="InterPro:IPR036396" /db_xref="PDB:3NC3" /db_xref="PDB:3NC5" /db_xref="PDB:3NC6" /db_xref="PDB:3NC7" /db_xref="SubtiList:BG12580" /db_xref="UniProtKB/Swiss-Prot:O34926" /translation="MSQSIKLFSVLSDQFQNNPYAYFSQLREEDPVHYEESIDSYFIS RYHDVRYILQHPDIFTTKSLVERAEPVMRGPVLAQMHGKEHSAKRRIVVRSFIGDALD HLSPLIKQNAENLLAPYLERGKSDLVNDFGKTFAVCVTMDMLGLDKRDHEKISEWHSG VADFITSISQSPEARAHSLWCSEQLSQYLMPVIKERRVNPGSDLISILCTSEYEGMAL SDKDILALILNVLLAATEPADKTLALMIYHLLNNPEQMNDVLADRSLVPRAIAETLRY KPPVQLIPRQLSQDTVVGGMEIKKDTIVFCMIGAANRDPEAFEQPDVFNIHREDLGIK SAFSGAARHLAFGSGIHNCVGAAFAKNEIEIVANIVLDKMRNIRLEEDFCYAESGLYT RGPVSLLVAFDGA*" gene complement(3468186..3469403) /gene="cypX" /locus_tag="BSU_35060" /old_locus_tag="BSU35060" downshifts complement(3468199) /Source="Nicolas_upshifts" /id="D1812" /incds=0 /nref=11 /ntot=50 /MaxReadThrough="2.27112" /MaxDrop="6.67384" /score="-0.264310319" /energy="-11.6" /TU="NA" /idTUdmin="U2747" /TUdmin=0 /isTUend="TRUE" promotor_-35 3468225..3468230 /Source="Nicolas_upshift_promotors" /id="U2746" /multdbtbs="-" /comp="M8" /sig="Sig-" /pcomp="0.437562437562438" /psig="0.437562437562438" /xcortree=409 /SigmaFactorBS="gtcaaacgcaacgagaagtgaaacaggtccGCGTGTatacag accggactCAGCATAACAAAaatcttcctctaatctgatattccgcatcttatccagc a" /listShort="S1335" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3468245..3468256 /Source="Nicolas_upshift_promotors" /id="U2746" /multdbtbs="-" /comp="M8" /sig="Sig-" /pcomp="0.437562437562438" /psig="0.437562437562438" /xcortree=409 /SigmaFactorBS="gtcaaacgcaacgagaagtgaaacaggtccGCGTGTatacag accggactCAGCATAACAAAaatcttcctctaatctgatattccgcatcttatccagc a" /listShort="S1335" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 3468255..3468540 /Source="Nicolas_S_feature" /locus_tag="new_3602657_3602942" /HighExp="BC, Sw, Lbstat, T5.0H, M9-stat, T4.0H, T3.30H, B60, T1.30H, T0.30H" /AntisenseName="cypX" /AntisenseCor="-4.04991056466339E-2" /AntisenseRegPval="-0.3" /CDS_PredictionProba="NA" /TUshortSig="Sig-, SigA" /TUshortPSig="0.438, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S1335" upshifts 3468255 /Source="Nicolas_upshifts" /id="U2746" /multdbtbs="-" /comp="M8" /sig="Sig-" /pcomp="0.437562437562438" /psig="0.437562437562438" /xcortree=409 /SigmaFactorBS="gtcaaacgcaacgagaagtgaaacaggtccGCGTGTatacag accggactCAGCATAACAAAaatcttcctctaatctgatattccgcatcttatccagc a" /listShort="S1335" /GFF_Attribute="listLong" downshifts 3468497 /Source="Nicolas_upshifts" /id="D1813" /incds=1 /nref=9 /ntot=165 /MaxReadThrough="3.27492" /MaxDrop="3.99509" /score="54.0406126" /energy="-11.4" /TU="U2745,U2746" /idTUdmin="U2746" /TUdmin="-44" /isTUend="FALSE" CDS complement(3469419..3470165) /gene="pchC" /locus_tag="BSU_35070" /old_locus_tag="BSU35070" /EC_number="6.-.-.-" /function="16.14: Store" /function="16.1: Circulate" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:4204912, 19430487, 27542896" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 4204912, 19430487, 27542896; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="cyclodipeptide synthase (tRNA-dependent), pulcherimminic acid precursor" /protein_id="NP_391387.1" /db_xref="EnsemblGenomes-Gn:BSU35070" /db_xref="EnsemblGenomes-Tr:CAB15512" /db_xref="GOA:O34351" /db_xref="InterPro:IPR030903" /db_xref="SubtiList:BG14121" /db_xref="UniProtKB/Swiss-Prot:O34351" /translation="MTGMVTERRSVHFIAEALTENCREIFERRRHVLVGISPFNSRFS EDYIYRLIGWAKAQFKSVSVLLAGHEAANLLEALGTPRGKAERKVRKEVSRNRRFAER ALVAHGGDPKAIHTFSDFIDNKAYQLLRQEVEHAFFEQPHFRHACLDMSREAIIGRAR GVSLMMEEVSEDMLNLAVEYVIAELPFFIGAPDILEVEETLLAYHRPWKLGEKISNHE FSICMRPNQGYLIVQEMAQMLSEKRITSEG*" gene complement(3469419..3470165) /gene="pchC" /locus_tag="BSU_35070" /old_locus_tag="BSU35070" S_feature complement(3470166..3470352) /Source="Nicolas_S_feature" /locus_tag="new_3604568_3604754_c" /HighExp="LBGstat, T1.30H, T2.0H, T2.30H, T3.0H, T1.0H, B36, BT, T3.30H, T4.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1336" promotor_-10 complement(3470338..3470357) /Source="Nicolas_upshift_promotors" /id="U2747" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.771228771228771" /psig=1 /xcortree=1627 /SigmaFactorBS="tacatttattttcaaatatttgggcacagatcatATTGACGT ttggaaggaaaagGGATAAAATGACTAATGTTTactagtaaacatttatcatgatatg g" /listShort="S1336, yvmC, cypX" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3470352) /Source="Nicolas_upshifts" /id="U2747" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.771228771228771" /psig=1 /xcortree=1627 /SigmaFactorBS="tacatttattttcaaatatttgggcacagatcatATTGACGT ttggaaggaaaagGGATAAAATGACTAATGTTTactagtaaacatttatcatgatatg g" /listShort="S1336, yvmC, cypX" /GFF_Attribute="listLong" promotor_-35 complement(3470371..3470378) /Source="Nicolas_upshift_promotors" /id="U2747" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.771228771228771" /psig=1 /xcortree=1627 /SigmaFactorBS="tacatttattttcaaatatttgggcacagatcatATTGACGT ttggaaggaaaagGGATAAAATGACTAATGTTTactagtaaacatttatcatgatatg g" /listShort="S1336, yvmC, cypX" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 3470486..3470493 /Source="Nicolas_upshift_promotors" /id="U2748" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.571428571428571" /psig="0.998001998001998" /xcortree=1628 /SigmaFactorBS="tatcaacaaatagtctaaacaccaacAATTGACAacgaaaac aagaaaAGATAAAATAAAATTGTTCAccagtaaacgatttgttttattgtttcatcgt a" /listShort="S1337, yvmB, yvmA, S1339" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3470508..3470527 /Source="Nicolas_upshift_promotors" /id="U2748" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.571428571428571" /psig="0.998001998001998" /xcortree=1628 /SigmaFactorBS="tatcaacaaatagtctaaacaccaacAATTGACAacgaaaac aagaaaAGATAAAATAAAATTGTTCAccagtaaacgatttgttttattgtttcatcgt a" /listShort="S1337, yvmB, yvmA, S1339" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3470520 /Source="Nicolas_upshifts" /id="U2748" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.571428571428571" /psig="0.998001998001998" /xcortree=1628 /SigmaFactorBS="tatcaacaaatagtctaaacaccaacAATTGACAacgaaaac aagaaaAGATAAAATAAAATTGTTCAccagtaaacgatttgttttattgtttcatcgt a" /listShort="S1337, yvmB, yvmA, S1339" /GFF_Attribute="listLong" S_feature 3470521..3470590 /Source="Nicolas_S_feature" /locus_tag="new_3604923_3604992" /HighExp="LBGstat, T1.30H, T2.0H, T2.30H, T1.0H, T0.30H, B36, T3.0H, BT, Salt" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.998" /TUlongSig="NA" /TUlongPSig="NA" /label="S1337" CDS 3470591..3471100 /gene="pchR" /locus_tag="BSU_35080" /old_locus_tag="BSU35080" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:27542896" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 27542896; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator for pulcherriminic acid synthesis" /protein_id="NP_391388.1" /db_xref="EnsemblGenomes-Gn:BSU35080" /db_xref="EnsemblGenomes-Tr:CAB15513" /db_xref="GOA:P40762" /db_xref="InterPro:IPR000835" /db_xref="InterPro:IPR023187" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG11018" /db_xref="UniProtKB/Swiss-Prot:P40762" /translation="MSDLTKQMIYDIYVRLLHLNEQKANTSLQQFFKEAAEEDVAEIP KNMTSIHVIDCIGQHEPINNAGIARKMNLSKANVTKISTKLIKEEFINSYQLTDNKKE VYFKLTRKGRRIFDLHEKLHKKKELAFYQFLDSFSQEEQKAVLKFLEQLTSTLEAEQT DGTPDKPVK*" gene 3470591..3471100 /gene="pchR" /locus_tag="BSU_35080" /old_locus_tag="BSU35080" S_feature complement(3470996..3472334) /Source="Nicolas_S_feature" /locus_tag="new_3605398_3606736_c" /HighExp="T0.30H, T1.0H, T1.30H, T-0.40H, T0.0H, T2.0H, G135, T2.30H, T-1.10H, G180" /AntisenseName="yvmA" /AntisenseCor="0.2423954904641" /AntisenseRegPval="-4.2" /CDS_PredictionProba="NA" /TUshortSig="SigWXY" /TUshortPSig=1 /TUlongSig="SigA" /TUlongPSig="0.993" /label="S1338" downshifts complement(3471037) /Source="Nicolas_upshifts" /id="D1814" /incds=1 /nref=1 /ntot=66 /MaxReadThrough="1.42525" /MaxDrop="2.72496" /score="14.1278884" /energy="-7.8" /TU="NA" /idTUdmin="U2749" /TUdmin=0 /isTUend="TRUE" CDS 3471121..3472332 /gene="pchE" /locus_tag="BSU_35090" /old_locus_tag="BSU35090" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:15849754, 16850406, 27542896" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15849754, 16850406, 27542896; Product type t: transporter" /codon_start=1 /transl_table=11 /product="pulcherriminic acid efflux transporter" /protein_id="NP_391389.1" /db_xref="EnsemblGenomes-Gn:BSU35090" /db_xref="EnsemblGenomes-Tr:CAB15514" /db_xref="GOA:O34307" /db_xref="InterPro:IPR011701" /db_xref="InterPro:IPR020846" /db_xref="InterPro:IPR036259" /db_xref="SubtiList:BG14120" /db_xref="UniProtKB/Swiss-Prot:O34307" /translation="MAHTKSKAVLILYTVCFSAFFASLSQNIYSPILPIIKESFHVST AMVNLSVSVFMIVTAIMQIILGAIIDFKGARIVLITGILATAAASIGCAVTTDFTLFL IFRMIQAAGSAALPLIAATTIGQLFTGNERGSAMGTYQMLLSVAPAIAPVLGGFIGGA AGYEGIFWILAAISIVLLVTNSITFPKDSPTESMQQAKGNVFAHYKSIFTNRTGNVIL TLSFVLFFIYFAVIVYLPILLTEHYHIDVGIAGLLYLPLALSTIAGTFLFKRIQAKIG LHTLFIGSNVIAACSIILFAVTHSVSLVLMALTLALFGISMGVIPPLYSTMITNEFEH NRGSAIGMFNFIRYTGMAAGPMVSAYLLTMMPSAMSFSLLGLGFAALSFCLLPPMFSP QKRTKQKKHHM*" gene 3471121..3472332 /gene="pchE" /locus_tag="BSU_35090" /old_locus_tag="BSU35090" downshifts 3472330 /Source="Nicolas_upshifts" /id="D1815" /incds=0 /nref=33 /ntot=196 /MaxReadThrough="5.27186" /MaxDrop="4.73361" /score="54.0406126" /energy="-11.4" /TU="U2748" /idTUdmin="U2748" /TUdmin="-721" /isTUend="FALSE" CDS complement(3472360..3472719) /gene="yvlD" /locus_tag="BSU_35100" /old_locus_tag="BSU35100" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406, 26296725; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative integral phage holin-like membrane protein" /protein_id="NP_391390.1" /db_xref="EnsemblGenomes-Gn:BSU35100" /db_xref="EnsemblGenomes-Tr:CAB15515" /db_xref="GOA:O34648" /db_xref="InterPro:IPR007165" /db_xref="SubtiList:BG14119" /db_xref="UniProtKB/Swiss-Prot:O34648" /translation="MVKWAVSILVNALLLIVIDGYIDSIHISSIGAAIIASLILSILN VLIKPLLIIFTLPVTMVTLGLFLFVINAITLMMTASIMGDSFQIDGFGTAIWASVILS VFHLLIQKGILEPLRKK*" gene complement(3472360..3472719) /gene="yvlD" /locus_tag="BSU_35100" /old_locus_tag="BSU35100" S_feature 3472375..3473091 /Source="Nicolas_S_feature" /locus_tag="new_3606777_3607493" /HighExp="LBGstat, S8, Gly, C30, G135, S7, C90, Sw, Fru, S6" /AntisenseName="yvlC" /AntisenseCor="0.178445666283919" /AntisenseRegPval="-2.5" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.998" /TUlongSig="NA" /TUlongPSig="NA" /label="S1339" downshifts complement(3472379) /Source="Nicolas_upshifts" /id="D1816" /incds=0 /nref=129 /ntot=265 /MaxReadThrough="4.63835" /MaxDrop="5.15146" /score="14.4434545" /energy="-9.6" /TU="U2749" /idTUdmin="U2751" /TUdmin=0 /isTUend="TRUE" CDS complement(3472721..3472918) /gene="yvlC" /locus_tag="BSU_35110" /old_locus_tag="BSU35110" /function="16.3: Control" /function="16.12: Sense" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 23980836; Product type r : regulator" /codon_start=1 /transl_table=11 /product="membrane associated phage-like stress regulator,nisin resistance" /protein_id="NP_391391.1" /db_xref="EnsemblGenomes-Gn:BSU35110" /db_xref="EnsemblGenomes-Tr:CAB15516" /db_xref="GOA:O34719" /db_xref="InterPro:IPR007168" /db_xref="SubtiList:BG14118" /db_xref="UniProtKB/Swiss-Prot:O34719" /translation="MNKLYRSEKNKKIAGVIGGLAEYFNWDASLLRVITVILAIMTSV LPVLLIYIIWIFIVPSERDMK*" gene complement(3472721..3472918) /gene="yvlC" /locus_tag="BSU_35110" /old_locus_tag="BSU35110" CDS complement(3472923..3474020) /gene="yvlB" /locus_tag="BSU_35120" /old_locus_tag="BSU35120" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 23980836" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function, stress-related" /protein_id="NP_391392.1" /db_xref="EnsemblGenomes-Gn:BSU35120" /db_xref="EnsemblGenomes-Tr:CAB15517" /db_xref="InterPro:IPR016599" /db_xref="InterPro:IPR025164" /db_xref="SubtiList:BG14117" /db_xref="UniProtKB/Swiss-Prot:O34628" /translation="MKQEKERILKLVEEGKLTAQEALTLIEKLDSDYKEKEEKITALS VHVHDEEEPFTTAKKESGKPSLGAKLFDWIDSAVKKVKEVDLDLNFGHAYDVQHIFQF KDTDFSSVELQIANGSVNIVPWEDDDIRAECQAKVYRADSQDAARHAFLQHIECEIKG NKFFIRTEKKTMKTNVTLYIPQKEYDKIRVKLFNGPVRGEHLHVKEFSAKTTNGVLSF SYLTAEKAIAETANGQIKLASHSCGTIEAETINGLIDLRGKSESIDVQSFNGNIAINV TESDCRSIYAKTTTGNVELAIPDDLAVKAELKSNLGTLSHELMDVEMLKEKNDTIQKE MMFTSNQAHDQNITVFSESLTGAIKLKYSQR*" gene complement(3472923..3474020) /gene="yvlB" /locus_tag="BSU_35120" /old_locus_tag="BSU35120" CDS complement(3474045..3474371) /gene="yvlA" /locus_tag="BSU_35130" /old_locus_tag="BSU35130" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 23980836" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_391393.1" /db_xref="EnsemblGenomes-Gn:BSU35130" /db_xref="EnsemblGenomes-Tr:CAB15518" /db_xref="GOA:O34322" /db_xref="SubtiList:BG14116" /db_xref="UniProtKB/Swiss-Prot:O34322" /translation="MNRNQAIIASLCYFSVFIAPIIVPIVAYFVVNEKETKRHAIRSL ISHIVPFVGWLFLFIALLGGAVAIDGDSLLPVFVIIGGAVIYFLVVIGIIIWNVIQGI KVLRAA*" gene complement(3474045..3474371) /gene="yvlA" /locus_tag="BSU_35130" /old_locus_tag="BSU35130" promotor_-10 complement(3474424..3474439) /Source="Nicolas_upshift_promotors" /id="U2749" /multdbtbs="SigW" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1667 /SigmaFactorBS="ccaatttccgtaaatcggagcatgtctaaagaatgaattTGA AACCTGAagagattttaaACGTATAAATAAGTAAaacgtccctgatcttttgtcatgg a" /listShort="yvlA, yvlB, yvlC, yvlD, S1338" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3474439) /Source="Nicolas_upshifts" /id="U2749" /multdbtbs="SigW" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1667 /SigmaFactorBS="ccaatttccgtaaatcggagcatgtctaaagaatgaattTGA AACCTGAagagattttaaACGTATAAATAAGTAAaacgtccctgatcttttgtcatgg a" /listShort="yvlA, yvlB, yvlC, yvlD, S1338" /GFF_Attribute="listLong" S_feature complement(3474441..3474931) /Source="Nicolas_S_feature" /locus_tag="new_3608843_3609333_c" /HighExp="H2O2, G180, Paraq, G150, G135, dia15, Oxctl, Diami, Lbexp, LBGexp" /AntisenseName="yvkN" /AntisenseCor="0.37678416921083902" /AntisenseRegPval="-9.8000000000000007" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.993" /TUlongSig="NA" /TUlongPSig="NA" /label="S1340" promotor_-35 complement(3474451..3474460) /Source="Nicolas_upshift_promotors" /id="U2749" /multdbtbs="SigW" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1667 /SigmaFactorBS="ccaatttccgtaaatcggagcatgtctaaagaatgaattTGA AACCTGAagagattttaaACGTATAAATAAGTAAaacgtccctgatcttttgtcatgg a" /listShort="yvlA, yvlB, yvlC, yvlD, S1338" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 3474519..3474522 /Source="Nicolas_upshift_promotors" /id="U2750" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.544455544455544" /psig="0.995004995004995" /xcortree=2993 /SigmaFactorBS="ttacggaaattggattttaaaaagttttagaaGTAGaatctt ccggctatACCGATTACAATATGTAAAAagcttacggcaaccaaggaggctggacaag c" /listShort="yvkN" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3474537..3474556 /Source="Nicolas_upshift_promotors" /id="U2750" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.544455544455544" /psig="0.995004995004995" /xcortree=2993 /SigmaFactorBS="ttacggaaattggattttaaaaagttttagaaGTAGaatctt ccggctatACCGATTACAATATGTAAAAagcttacggcaaccaaggaggctggacaag c" /listShort="yvkN" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3474547 /Source="Nicolas_upshifts" /id="U2750" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.544455544455544" /psig="0.995004995004995" /xcortree=2993 /SigmaFactorBS="ttacggaaattggattttaaaaagttttagaaGTAGaatctt ccggctatACCGATTACAATATGTAAAAagcttacggcaaccaaggaggctggacaag c" /listShort="yvkN" /GFF_Attribute="listLong" CDS 3474589..3474819 /gene="yvkN" /locus_tag="BSU_35140" /old_locus_tag="BSU35140" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_391394.1" /db_xref="EnsemblGenomes-Gn:BSU35140" /db_xref="EnsemblGenomes-Tr:CAB15519" /db_xref="SubtiList:BG14115" /db_xref="UniProtKB/Swiss-Prot:O34604" /translation="MEKDPSDYTVTQESVLKLIQEQKRMNREMITELEQIHGPFPISH DIQYIKVLLDSSNTHIVQDLMSVSKQLYKKTL*" gene 3474589..3474819 /gene="yvkN" /locus_tag="BSU_35140" /old_locus_tag="BSU35140" promotor_-10 complement(3474922..3474941) /Source="Nicolas_upshift_promotors" /id="U2751" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.845154845154845" /psig="0.993006993006993" /xcortree=1844 /SigmaFactorBS="agttacagcttgccgacagagtccattaactGGATGtgccgg caggcttttTTTGTTACAATCATTTTGTGacagccagggaatcacttgttttttcaaa a" /listShort="S1340, yvlA, yvlB, yvlC, yvlD" /listLong="S1338" /label="promotor_-10" upshifts complement(3474932) /Source="Nicolas_upshifts" /id="U2751" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.845154845154845" /psig="0.993006993006993" /xcortree=1844 /SigmaFactorBS="agttacagcttgccgacagagtccattaactGGATGtgccgg caggcttttTTTGTTACAATCATTTTGTGacagccagggaatcacttgttttttcaaa a" /listShort="S1340, yvlA, yvlB, yvlC, yvlD" /listLong="S1338" promotor_-35 complement(3474957..3474961) /Source="Nicolas_upshift_promotors" /id="U2751" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.845154845154845" /psig="0.993006993006993" /xcortree=1844 /SigmaFactorBS="agttacagcttgccgacagagtccattaactGGATGtgccgg caggcttttTTTGTTACAATCATTTTGTGacagccagggaatcacttgttttttcaaa a" /listShort="S1340, yvlA, yvlB, yvlC, yvlD" /listLong="S1338" /label="promotor_-35" CDS complement(3475018..3475500) /gene="yvzB" /locus_tag="BSU_35150" /old_locus_tag="BSU35150" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 16936039; Product type s: structure" /pseudo /codon_start=1 /transl_table=11 /product="putative flagellin" /db_xref="EnsemblGenomes-Gn:BSU35150" /db_xref="EnsemblGenomes-Tr:CAB15520" /db_xref="GOA:O34366" /db_xref="InterPro:IPR001029" /db_xref="PSEUDO:CAB15520.1" /db_xref="SubtiList:BG14158" /db_xref="UniProtKB/Swiss-Prot:O34366" /translation="MDALIEEVDGISNRTEFNGKKLLDGTETDGFTFQIGANAGQQLT VNIDSMSSTALGVNALNVTDFANTPFDTQLESIDTAINNVSNQRAKLGAVQNRLEHTI NNLGASSENLTAAESRIRDVDMAKEMSEFTKNNIPSQASQAMLAQANQQPQNVLQLLR *" gene complement(3475018..3475500) /gene="yvzB" /locus_tag="BSU_35150" /old_locus_tag="BSU35150" /pseudo downshifts 3475026 /Source="Nicolas_upshifts" /id="D1817" /incds=0 /nref=13 /ntot=113 /MaxReadThrough="0.9814" /MaxDrop="4.76969" /score="2.6592903" /energy="-5.7" /TU="NA" /idTUdmin="U2750" /TUdmin=17 /isTUend="TRUE" downshifts complement(3475041) /Source="Nicolas_upshifts" /id="D1818" /incds=0 /nref=118 /ntot=206 /MaxReadThrough="2.62918" /MaxDrop="8.97968" /score="25.6132739" /energy="-19.8" /TU="NA" /idTUdmin="U2752" /TUdmin=0 /isTUend="TRUE" upshifts complement(3475173) /Source="Nicolas_upshifts" /id="U2752" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.96003996003996" /psig="0.011988011988012" /xcortree=15 /SigmaFactorBS="aaacttggtgcggtacaaaaccgtctagagcacacaatcaac aaccttgGTGCttcttctgaaaacctgacagctgctgagtcccgtatccgtgacgttg a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" misc_feature complement(3475181..3475184) /Source="Nicolas_upshift_promotors" /id="U2752" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.96003996003996" /psig="0.011988011988012" /xcortree=15 /SigmaFactorBS="aaacttggtgcggtacaaaaccgtctagagcacacaatcaac aaccttgGTGCttcttctgaaaacctgacagctgctgagtcccgtatccgtgacgttg a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" promotor_-10 complement(3475261..3475265) /Source="Nicolas_upshift_promotors" /id="U2753" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.831168831168831" /psig="0.154845154845155" /xcortree=16 /SigmaFactorBS="taatgtaacagattttgctaatactccttttgatacaCAACt tgaaagtattgataCTGCAatcaacaatgtctcaaaccaacgtgctaaacttggtgcg g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3475261) /Source="Nicolas_upshifts" /id="U2753" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.831168831168831" /psig="0.154845154845155" /xcortree=16 /SigmaFactorBS="taatgtaacagattttgctaatactccttttgatacaCAACt tgaaagtattgataCTGCAatcaacaatgtctcaaaccaacgtgctaaacttggtgcg g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(3475281..3475284) /Source="Nicolas_upshift_promotors" /id="U2753" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.831168831168831" /psig="0.154845154845155" /xcortree=16 /SigmaFactorBS="taatgtaacagattttgctaatactccttttgatacaCAACt tgaaagtattgataCTGCAatcaacaatgtctcaaaccaacgtgctaaacttggtgcg g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" S_feature complement(3475501..3475634) /Source="Nicolas_S_feature" /locus_tag="new_3609903_3610036_c" /HighExp="H2O2, Sw, M40t45, M40t90, Diami, Salt, dia15, BC, G135, C90" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigB" /TUshortPSig="1, 1" /TUlongSig="SigA" /TUlongPSig=1 /label="S1341" CDS complement(3475662..3478535) /gene="uvrA" /locus_tag="BSU_35160" /old_locus_tag="BSU35160" /function="16.8: Protect" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:11751826, 16267290, 16426634, 25713353, 27399782" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11751826, 16267290, 16426634, 25713353, 27399782; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="excinuclease ABC (subunit A)" /protein_id="NP_391396.1" /db_xref="EnsemblGenomes-Gn:BSU35160" /db_xref="EnsemblGenomes-Tr:CAB15533" /db_xref="GOA:O34863" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR004602" /db_xref="InterPro:IPR017871" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG12697" /db_xref="UniProtKB/Swiss-Prot:O34863" /translation="MAMDRIEVKGARAHNLKNIDVTIPRDQLVVVTGLSGSGKSSLAF DTIYAEGQRRYVESLSAYARQFLGQMDKPDVDAIEGLSPAISIDQKTTSRNPRSTVGT VTEIYDYLRLLYARVGKPHCPEHGIEITSQTIEQMVDRILEYPERTKLQVLAPIVSGR KGAHVKVLEQIRKQGYVRVRIDGEMAELSDDIELEKNKKHSIEVVIDRIVVKEGVAAR LSDSLETALRLGEGRVMIDVIGEEELMFSEHHACPHCGFSIGELEPRLFSFNSPFGAC PTCDGLGMKLEVDADLVIPNQDLSLKENAVAPWTPISSQYYPQLLEAVCTHYGIDMDV PVKDLPKHQLDKVLYGSGDDLIYFRYENDFGQIREGEIQFEGVLRNIERRYKETGSDF IREQMEQYMSQKSCPTCKGYRLKKEALAVLIDGRHIGKITELSVADALAFFKDLTLSE KDMQIANLILREIVERLSFLDKVGLDYLTLSRAAGTLSGGEAQRIRLATQIGSRLSGV LYILDEPSIGLHQRDNDRLISALKNMRDLGNTLIVVEHDEDTMMAADYLIDIGPGAGI HGGQVISAGTPEEVMEDPNSLTGSYLSGKKFIPLPPERRKPDGRYIEIKGASENNLKK VNAKFPLGTFTAVTGVSGSGKSTLVNEILHKALAQKLHKAKAKPGSHKEIKGLDHLDK VIDIDQAPIGRTPRSNPATYTGVFDDIRDVFAQTNEAKVRGYKKGRFSFNVKGGRCEA CRGDGIIKIEMHFLPDVYVPCEVCHGKRYNRETLEVTYKGKSISDVLDMTVEDALSFF ENIPKIKRKLQTLYDVGLGYITLGQPATTLSGGEAQRVKLASELHKRSTGRTLYILDE PTTGLHVDDIARLLVVLQRLVDNGDTVLVIEHNLDIIKTADYIVDLGPEGGAGGGTIV ASGTPEEITEVEESYTGRYLKPVIERDKTRMKSLLKAKETATS*" gene complement(3475662..3478535) /gene="uvrA" /locus_tag="BSU_35160" /old_locus_tag="BSU35160" downshifts complement(3475679) /Source="Nicolas_upshifts" /id="D1819" /incds=0 /nref=240 /ntot=268 /MaxReadThrough="4.46283" /MaxDrop="5.3695" /score="12.0157254" /energy="-18.6" /TU="U2754,U2756" /idTUdmin="U2755" /TUdmin=0 /isTUend="TRUE" CDS complement(3478543..3480528) /gene="uvrB" /locus_tag="BSU_35170" /old_locus_tag="BSU35170" /function="16.8: Protect" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:11751826, 16267290, 16426634, 25713353, 27399782" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11751826, 16267290, 16426634, 25713353, 27399782; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="excinuclease ABC (subunit B)" /protein_id="NP_391397.1" /db_xref="EnsemblGenomes-Gn:BSU35170" /db_xref="EnsemblGenomes-Tr:CAB15534" /db_xref="GOA:P37954" /db_xref="InterPro:IPR001650" /db_xref="InterPro:IPR001943" /db_xref="InterPro:IPR004807" /db_xref="InterPro:IPR006935" /db_xref="InterPro:IPR014001" /db_xref="InterPro:IPR024759" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR036876" /db_xref="PDB:2D7D" /db_xref="PDB:2NMV" /db_xref="PDB:3V4R" /db_xref="SubtiList:BG10502" /db_xref="UniProtKB/Swiss-Prot:P37954" /translation="MKDRFELVSKYQPQGDQPKAIEKLVKGIQEGKKHQTLLGATGTG KTFTVSNLIKEVNKPTLVIAHNKTLAGQLYSEFKEFFPNNAVEYFVSYYDYYQPEAYV PQTDTFIEKDASINDEIDKLRHSATSALFERRDVIIIASVSCIYGLGSPEEYREMVVS LRTEMEIERNELLRKLVDIQYARNDIDFQRGTFRVRGDVVEIFPASRDEHCVRVEFFG DEIERIREVDALTGEILGDRDHVAIFPASHFVTRAEKMEKAIQNIEKELEEQLKVMHE NGKLLEAQRLEQRTRYDLEMMREMGFCSGIENYSRHLTLRPPGSTPYTLLDYFPDDFM IVVDESHVTIPQVRGMFNGDQARKQVLVDHGFRLPSALDNRPLRFEEFEKHMHNIVYV SATPGPYEIEHTDEMVEQIIRPTGLLDPLIDVRPIEGQIDDLIGEIQARIERNERVLV TTLTKKMSEDLTDYLKEIGIKVNYLHSEIKTLERIEIIRDLRLGKYDVLVGINLLREG LDIPEVSLVAILDADKEGFLRSERSLIQTIGRAARNAEGRVIMYADKITKSMEIAINE TKRRREQQERFNEEHGITPKTINKEIRDVIRATVAAEDKAEYKTKAAPKLSKMTKKER QKVVEQMEHEMKEAAKALDFERAAELRDLLLELKAEG*" gene complement(3478543..3480528) /gene="uvrB" /locus_tag="BSU_35170" /old_locus_tag="BSU35170" promotor_-10 complement(3480562..3480581) /Source="Nicolas_upshift_promotors" /id="U2754" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.756243756243756" /psig=1 /xcortree=2093 /SigmaFactorBS="aaataaaaaaccaccgaactttagttcgtattttTAGTGATT ttgctttccatTGTGTTACTATATCTATAGGaagatttcgttaaagaaacggaggctt a" /listShort="uvrB, uvrA, S1341, yvzB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3480574) /Source="Nicolas_upshifts" /id="U2754" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.756243756243756" /psig=1 /xcortree=2093 /SigmaFactorBS="aaataaaaaaccaccgaactttagttcgtattttTAGTGATT ttgctttccatTGTGTTACTATATCTATAGGaagatttcgttaaagaaacggaggctt a" /listShort="uvrB, uvrA, S1341, yvzB" /GFF_Attribute="listLong" S_feature complement(3480576..3480661) /Source="Nicolas_S_feature" /locus_tag="new_3614978_3615063_c" /HighExp="Gly, Sw, B60, BT, LoTm, Salt, Etha, M9-stat, B36, S0" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigB" /TUshortPSig="1, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S1342" promotor_-35 complement(3480593..3480600) /Source="Nicolas_upshift_promotors" /id="U2754" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.756243756243756" /psig=1 /xcortree=2093 /SigmaFactorBS="aaataaaaaaccaccgaactttagttcgtattttTAGTGATT ttgctttccatTGTGTTACTATATCTATAGGaagatttcgttaaagaaacggaggctt a" /listShort="uvrB, uvrA, S1341, yvzB" /GFF_Attribute="listLong" /label="promotor_-35" downshifts complement(3480706) /Source="Nicolas_upshifts" /id="D1820" /incds=0 /nref=4 /ntot=60 /MaxReadThrough="5.68784" /MaxDrop="3.17938" /score="11.285993" /energy="-12" /TU="U2755,U2756" /idTUdmin="U2755" /TUdmin="-5027" /isTUend="FALSE" CDS complement(3480714..3480944) /gene="csbA" /locus_tag="BSU_35180" /old_locus_tag="BSU35180" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 1592822, 1744042; Product type m:membrane component" /codon_start=1 /transl_table=11 /product="conserved membrane protein of unknown function" /protein_id="NP_391398.1" /db_xref="EnsemblGenomes-Gn:BSU35180" /db_xref="EnsemblGenomes-Tr:CAB15535" /db_xref="GOA:P37953" /db_xref="InterPro:IPR019242" /db_xref="SubtiList:BG10501" /db_xref="UniProtKB/Swiss-Prot:P37953" /translation="MITKAVFALFFPFMLVVLFTRVTFNHYVAIALTAALLFASYLKG YTETYFIVGLDVVSLVAGGLYMAKKAAEKKEE*" gene complement(3480714..3480944) /gene="csbA" /locus_tag="BSU_35180" /old_locus_tag="BSU35180" promotor_-10 complement(3480971..3480990) /Source="Nicolas_upshift_promotors" /id="U2755" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.61038961038961" /psig=1 /xcortree=598 /SigmaFactorBS="ggtatggtgtaagtagagggagcgaatgcaCGATTGTCcgat tcttcatttTTTACTATAATCAGATCAGAtgaagaatccctgaggagggtttttgttg a" /listShort="csbA, S1342, uvrB, uvrA" /listLong="S1341, yvzB" /label="promotor_-10" upshifts complement(3480981) /Source="Nicolas_upshifts" /id="U2755" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.61038961038961" /psig=1 /xcortree=598 /SigmaFactorBS="ggtatggtgtaagtagagggagcgaatgcaCGATTGTCcgat tcttcatttTTTACTATAATCAGATCAGAtgaagaatccctgaggagggtttttgttg a" /listShort="csbA, S1342, uvrB, uvrA" /listLong="S1341, yvzB" S_feature complement(3480983..3481047) /Source="Nicolas_S_feature" /locus_tag="new_3615385_3615449_c" /HighExp="Gly, M9-stat, B60, Sw, Etha, LoTm, BT, B36, T1.30H, T2.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigB" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1343" promotor_-35 complement(3481004..3481011) /Source="Nicolas_upshift_promotors" /id="U2755" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.61038961038961" /psig=1 /xcortree=598 /SigmaFactorBS="ggtatggtgtaagtagagggagcgaatgcaCGATTGTCcgat tcttcatttTTTACTATAATCAGATCAGAtgaagaatccctgaggagggtttttgttg a" /listShort="csbA, S1342, uvrB, uvrA" /listLong="S1341, yvzB" /label="promotor_-35" promotor_-10 complement(3481024..3481042) /Source="Nicolas_upshift_promotors" /id="U2756" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=196 /SigmaFactorBS="accatggaataagttttgaccggcaccaaaatgcaaatatgg TGATTGAttttggctgaaaagGGGTATGGTGTAAGTAGAGggagcgaatgcacgattg t" /listShort="S1343, csbA, S1342, uvrB, uvrA, S1341, yvzB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3481045) /Source="Nicolas_upshifts" /id="U2756" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=196 /SigmaFactorBS="accatggaataagttttgaccggcaccaaaatgcaaatatgg TGATTGAttttggctgaaaagGGGTATGGTGTAAGTAGAGggagcgaatgcacgattg t" /listShort="S1343, csbA, S1342, uvrB, uvrA, S1341, yvzB" /GFF_Attribute="listLong" promotor_-35 complement(3481057..3481063) /Source="Nicolas_upshift_promotors" /id="U2756" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=196 /SigmaFactorBS="accatggaataagttttgaccggcaccaaaatgcaaatatgg TGATTGAttttggctgaaaagGGGTATGGTGTAAGTAGAGggagcgaatgcacgattg t" /listShort="S1343, csbA, S1342, uvrB, uvrA, S1341, yvzB" /GFF_Attribute="listLong" /label="promotor_-35" downshifts complement(3481113) /Source="Nicolas_upshifts" /id="D1821" /incds=0 /nref=1 /ntot=9 /MaxReadThrough="0.9693" /MaxDrop="4.37808" /score="-1.92287727" /energy="-4.2" /TU="NA" /idTUdmin="U2761" /TUdmin=4752 /isTUend="FALSE" promotor_no_box complement(3481139..3481239) /Source="Nicolas_upshift_promotors" /id="U2757" /multdbtbs="-" /comp="M21" /sig="Sig-" /pcomp="0.236763236763237" /psig="0.378621378621379" /xcortree=1470 /SigmaFactorBS="aatagttaagttggttatattatcctgaaaaatgcggccgta ctggtactgtatgcctattttcttttattctcggaatctggcggcggacttgatgatg t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_no_box" upshifts complement(3481179) /Source="Nicolas_upshifts" /id="U2757" /multdbtbs="-" /comp="M21" /sig="Sig-" /pcomp="0.236763236763237" /psig="0.378621378621379" /xcortree=1470 /SigmaFactorBS="aatagttaagttggttatattatcctgaaaaatgcggccgta ctggtactgtatgcctattttcttttattctcggaatctggcggcggacttgatgatg t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 3481261..3481268 /Source="Nicolas_upshift_promotors" /id="U2758" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.608391608391608" /psig="0.999000999001" /xcortree=566 /SigmaFactorBS="tcattttatttaggactttctgCGTTTGACagcattttcctg aAAACCTACAATTAAATGATAgtgtttactatcattttttaaacacaggctccgcaat a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3481282..3481301 /Source="Nicolas_upshift_promotors" /id="U2758" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.608391608391608" /psig="0.999000999001" /xcortree=566 /SigmaFactorBS="tcattttatttaggactttctgCGTTTGACagcattttcctg aAAACCTACAATTAAATGATAgtgtttactatcattttttaaacacaggctccgcaat a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3481299 /Source="Nicolas_upshifts" /id="U2758" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.608391608391608" /psig="0.999000999001" /xcortree=566 /SigmaFactorBS="tcattttatttaggactttctgCGTTTGACagcattttcctg aAAACCTACAATTAAATGATAgtgtttactatcattttttaaacacaggctccgcaat a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" CDS 3481391..3483886 /gene="yvkC" /locus_tag="BSU_35190" /old_locus_tag="BSU35190" /EC_number="2.7.-.-" /function="16.13: Shape" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 25012659; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative phosphotransferase" /protein_id="NP_391399.1" /db_xref="EnsemblGenomes-Gn:BSU35190" /db_xref="EnsemblGenomes-Tr:CAB15536" /db_xref="GOA:O34796" /db_xref="InterPro:IPR002192" /db_xref="InterPro:IPR008279" /db_xref="InterPro:IPR013815" /db_xref="SubtiList:BG14114" /db_xref="UniProtKB/Swiss-Prot:O34796" /translation="MYSVLFRQAEESSQLAGAKGMNLIKLTKHGLPVPDGFIIQTNAL ARFMEDNQLQETSENVEGGIISGTFSDELKDELTSSFYKLRESYRSVAVRSSSASEDL EGASFAGQYETYLNIKTEEEFLAKVKECWASFFSGRVSSYKKKMNNQIAEPLMGIVVQ GLIDSEMSGVIFSRNPVTHDDRELLISASYGLGEAVVSGNVTPDTFIVNKSSFEIQKE IGAKEIYMESAAEGIAEKETSEDMRSRFCLTDEQVIELAEITKKTEDLYGYPVDIEFG IADHQIYLLQARPITTIDQDKKAAEEKRSFMITDTDMNDFWLNMESNIEGPVSPLFSS FIVPALEYGLKKSMQKFPIGVVVDEVKLYRGHIYSKNQGGQQPPSEDCGKELFPILSE HMYDIINHTYLPFYRTLDQLAQTEHTAESALEAFQKLKAFYLTAYEEHFNIVFPQILL TNKLQAMYQDIQGESENAHFYEMLTGKMNKSLETDRCLWLFSVEVQENPNLLAIFENN KPEQLQEKLEQTDEGRHFLKNVHEFLQEYGWRSVKSHDLIEQIWVENPYFALANIQNY VRNGYHFDNEFQKTKEKREKLYNEFLESIEDPGLRTEFDRYYQWTLNSANIKDDHHFY IDAMLDAKARIFLLKIGELLAENGVIQDREDLWFLYDDEVEQALLHPVSLQEKAEKRR QIFHEYELAQAPAYLGTPTKEQLKAAEEIVGAVIEDEKNTENHIFGIAASSGIATGPV KIIRDANEFSQFAPGDVLVCKMTTPLWTSLFQDAKAIITDTGGILSHAAIIAREYGIP AVLGTRTATERLRDGDIITVDGSSGKITVVSRS*" gene 3481391..3483886 /gene="yvkC" /locus_tag="BSU_35190" /old_locus_tag="BSU35190" misc_feature 3483901..3483905 /Source="Nicolas_upshift_promotors" /id="U2759" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.358641358641359" /psig="0.448551448551449" /xcortree=2520 /SigmaFactorBS="caaaatcacagttgtcagccggtcctgatgcgtccccctctt TCTTAtacaagcggggcgggtgtatacttgtcctgccagtatattcgtgaggtgaaac g" /listShort="yvkB" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 3483919 /Source="Nicolas_upshifts" /id="U2759" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.358641358641359" /psig="0.448551448551449" /xcortree=2520 /SigmaFactorBS="caaaatcacagttgtcagccggtcctgatgcgtccccctctt TCTTAtacaagcggggcgggtgtatacttgtcctgccagtatattcgtgaggtgaaac g" /listShort="yvkB" /GFF_Attribute="listLong" CDS 3483962..3484531 /gene="yvkB" /locus_tag="BSU_35200" /old_locus_tag="BSU35200" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative transcriptional regulator (TetR/AcrR family)" /protein_id="NP_391400.1" /db_xref="EnsemblGenomes-Gn:BSU35200" /db_xref="EnsemblGenomes-Tr:CAB15537" /db_xref="GOA:O34643" /db_xref="InterPro:IPR001647" /db_xref="InterPro:IPR009057" /db_xref="SubtiList:BG14113" /db_xref="UniProtKB/Swiss-Prot:O34643" /translation="MRPTNKRILDAAMQLLVKKGYRATTTKEIAEKANVSEATIFRNF KNKQGLVEALLSQHSSNRGSILEQTEGDLYKDLLHIGTCLLEELEHRKDIIKISFREP AMFQDVINHVTEYPQSMKQLLVDYLKTMGEKGVIQTGNEAEHADVFMSIIFGYFIHRL HLGDRVISMPQEKMLEHSTALFVKGISAD*" gene 3483962..3484531 /gene="yvkB" /locus_tag="BSU_35200" /old_locus_tag="BSU35200" CDS 3484562..3485896 /gene="yvkA" /locus_tag="BSU_35210" /old_locus_tag="BSU35210" /function="16.1: Circulate" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative efflux transporter" /protein_id="NP_391401.1" /db_xref="EnsemblGenomes-Gn:BSU35210" /db_xref="EnsemblGenomes-Tr:CAB15538" /db_xref="GOA:O34502" /db_xref="InterPro:IPR011701" /db_xref="InterPro:IPR020846" /db_xref="InterPro:IPR036259" /db_xref="SubtiList:BG14112" /db_xref="UniProtKB/Swiss-Prot:O34502" /translation="MSSRKEWALIVSLLLGAILVPINSTMIAVALSSISHTYNESIAS ITWVVTVYLIVMAVTQPIAGKLGDMYGNKTMYLWGVGLFLIASLGCALSPSLLLLIVF RALQAVGGALLTPNSIAIIRHVVSEKRLPKVFGFFGLGAGLGAALGPFIGSILIDSFS WHSIFWVNIPFLAIALFTALTMFPQYKENKSDAPLDIIGSLLLAGSIVSIILLTKNEA PWGYTVYSVLILLFVPLFFRREKRTQHPIIDFALFKSSTFTNANLSVLLSNLMMYAVL LIMPLFMTNQFGLNTSNSGMALSVFSIFMSASNWVGAQLHHKWGAKKIIFLSFAMMAG ANLLFLLLSSSHSVLFLMLSLILGGLASGVGLTSMQVSSLATVDPGMSGVASGIFSTF RYFGSIISSALIGLISGYHTLFMILFAVSIIGVFVSLGIKSDETARIEKNSA*" gene 3484562..3485896 /gene="yvkA" /locus_tag="BSU_35210" /old_locus_tag="BSU35210" downshifts 3485877 /Source="Nicolas_upshifts" /id="D1822" /incds=0 /nref=4 /ntot=118 /MaxReadThrough="0.94661" /MaxDrop="3.57731" /score="21.0606505" /energy="-28.8" /TU="NA" /idTUdmin="U2759" /TUdmin=1276 /isTUend="FALSE" CDS complement(3485944..3487137) /gene="minJ" /locus_tag="BSU_35220" /old_locus_tag="BSU35220" /function="16.5: Explore" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:15849754, 16030230, 16850406, 18976281, 19019154, 26735940" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15849754, 16030230, 16850406, 18976281, 19019154, 26735940; Product type cp : cell process" /codon_start=1 /transl_table=11 /product="topological determinant of cell division" /protein_id="NP_391402.1" /db_xref="EnsemblGenomes-Gn:BSU35220" /db_xref="EnsemblGenomes-Tr:CAB15539" /db_xref="GOA:O34375" /db_xref="InterPro:IPR001478" /db_xref="InterPro:IPR036034" /db_xref="SubtiList:BG14111" /db_xref="UniProtKB/Swiss-Prot:O34375" /translation="MSVQWGIELLKSAGLFFLHPLFWFFIIITLAFGYVRIKRERKTF HTRIADIYDDLKFTYTKGLIPGLLLSVILGGLGISIPLGLLAIIAVITAAAAFTLRAN WMSAAYIVSVSMLIGFGLQIYQAEPFLERFPQGFAVVWPAVAVFLGLLIITEGAVAYR SAHVRTSPALVVSSRGLPIGQQLANRVWLLPLFLLVPGNGLESHLSWWPVFTVPGGSF HFLWIPYFVGFGQRVQGSLPETSIRITAKRVCILGLAVAVLGAASLLWTPLAGAAVCT ALLGRIFLSIKQRVNDNAAPFYFSKRDQGLMVLGIIPNTPAEDLELKIGEIITKVNGI PVKNVSDFYEALQHNRAYVKLEIIGLNGEIRFDQRASYEGEHHELGILFVKDDREDEA VASGS*" gene complement(3485944..3487137) /gene="minJ" /locus_tag="BSU_35220" /old_locus_tag="BSU35220" downshifts complement(3485953) /Source="Nicolas_upshifts" /id="D1823" /incds=0 /nref=3 /ntot=85 /MaxReadThrough="3.18641" /MaxDrop="3.13207" /score="21.4231982" /energy="-25.6" /TU="U2761" /idTUdmin="U2760" /TUdmin=66 /isTUend="FALSE" downshifts complement(3486018) /Source="Nicolas_upshifts" /id="D1824" /incds=1 /nref=94 /ntot=239 /MaxReadThrough="4.11808" /MaxDrop="4.31508" /score="21.4231982" /energy="-25.6" /TU="U2761" /idTUdmin="U2760" /TUdmin=1 /isTUend="TRUE" S_feature complement(3487138..3487215) /Source="Nicolas_S_feature" /locus_tag="new_3621540_3621617_c" /HighExp="LBGstat, Lbstat, M0t90, Cold, M/G, GM 10, GM 25, GM 15, GM 60, GM 45" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigD, SigGF" /TUshortPSig="0.945, 0.998, 0.992" /TUlongSig="NA" /TUlongPSig="NA" /label="S1344" downshifts complement(3487141) /Source="Nicolas_upshifts" /id="D1825" /incds=0 /nref=1 /ntot=13 /MaxReadThrough="6.36185" /MaxDrop="3.35962" /score="-9.46264764" /energy="-7.1" /TU="U2760,U2761,U2762" /idTUdmin="U2762" /TUdmin="-220" /isTUend="FALSE" CDS complement(3487216..3487554) /gene="swrAAc" /locus_tag="BSU_35230" /old_locus_tag="BSU35230" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:15066026, 16030230" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15066026, 16030230; Product type cp: cell process" /pseudo /codon_start=1 /transl_table=11 /product="swarming motility protein fragment; C-terminal part of swrAA" /db_xref="GOA:O32266" /db_xref="InterPro:IPR035388" /db_xref="PSEUDO:CAB15540.1" /db_xref="SubtiList:BG14160" /db_xref="UniProtKB/Swiss-Prot:O32266" /translation="MCVKKKYYELVEQLKDRTQDVTFSATKALSLLMLFSRYLVNYTN VESVNDINEECAKHYFNYLMKNHKRLGINLTDIKRSMHLISGLLDVDVNHYLKDFSLS NVTLWMTQER*" gene complement(3487216..3487554) /gene="swrAAc" /locus_tag="BSU_35230" /old_locus_tag="BSU35230" /pseudo CDS complement(3487529..3487645) /gene="swrAAn" /locus_tag="BSU_35239" /old_locus_tag="BSU35239" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1a: Function from experimental evidences in the studied strain; Product type cp: cell process" /pseudo /codon_start=1 /transl_table=11 /product="swarming motility protein; N-terminal part of swrAA" /db_xref="PSEUDO:CAX52697.1" /translation="MLVSTPVLLLILARAYLYKENGGSQLKRASIVREKKIL*" gene complement(3487529..3487645) /gene="swrAAn" /locus_tag="BSU_35239" /old_locus_tag="BSU35239" /pseudo S_feature complement(3487646..3487735) /Source="Nicolas_S_feature" /locus_tag="new_3622048_3622137_c" /HighExp="LBGstat, M0t90, Cold, Lbstat, GM 25, Gly, nit, GM 15, GM 10, M/G" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigD, SigGF" /TUshortPSig="0.945, 0.998, 0.992" /TUlongSig="NA" /TUlongPSig="NA" /label="S1345" promotor_-10 complement(3487717..3487735) /Source="Nicolas_upshift_promotors" /id="U2760" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.494505494505495" /psig="0.945054945054945" /xcortree=2762 /SigmaFactorBS="ttctaacgagttaatatgcatttaaaatgaaacttttgcaaG TTGCCtagtctttgtttaCTTCATACAATATAAGAAGgttctaaaaagaacagtaatc a" /listShort="S1345, swrAA, swrAA, S1344, minJ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3487735) /Source="Nicolas_upshifts" /id="U2760" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.494505494505495" /psig="0.945054945054945" /xcortree=2762 /SigmaFactorBS="ttctaacgagttaatatgcatttaaaatgaaacttttgcaaG TTGCCtagtctttgtttaCTTCATACAATATAAGAAGgttctaaaaagaacagtaatc a" /listShort="S1345, swrAA, swrAA, S1344, minJ" /GFF_Attribute="listLong" S_feature complement(3487737..3487817) /Source="Nicolas_S_feature" /locus_tag="new_3622139_3622219_c" /HighExp="LBGstat, Lbstat, Cold, M0t90, GM 25, nit, Gly, M/G, MG 150, GM 150" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigD, SigGF" /TUshortPSig="0.998, 0.992" /TUlongSig="NA" /TUlongPSig="NA" /label="S1346" promotor_-35 complement(3487749..3487754) /Source="Nicolas_upshift_promotors" /id="U2760" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.494505494505495" /psig="0.945054945054945" /xcortree=2762 /SigmaFactorBS="ttctaacgagttaatatgcatttaaaatgaaacttttgcaaG TTGCCtagtctttgtttaCTTCATACAATATAAGAAGgttctaaaaagaacagtaatc a" /listShort="S1345, swrAA, swrAA, S1344, minJ" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(3487803..3487821) /Source="Nicolas_upshift_promotors" /id="U2761" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=2797 /SigmaFactorBS="ttgacaagaaattaaaaaaattttcacaaataaacATTTATA AaggactgttattaCCCGATATCAATATATGAGagagactttctaacgagttaatatg c" /listShort="S1346, S1345, swrAA, swrAA, S1344, minJ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3487817) /Source="Nicolas_upshifts" /id="U2761" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=2797 /SigmaFactorBS="ttgacaagaaattaaaaaaattttcacaaataaacATTTATA AaggactgttattaCCCGATATCAATATATGAGagagactttctaacgagttaatatg c" /listShort="S1346, S1345, swrAA, swrAA, S1344, minJ" /GFF_Attribute="listLong" promotor_-35 complement(3487835..3487842) /Source="Nicolas_upshift_promotors" /id="U2761" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=2797 /SigmaFactorBS="ttgacaagaaattaaaaaaattttcacaaataaacATTTATA AaggactgttattaCCCGATATCAATATATGAGagagactttctaacgagttaatatg c" /listShort="S1346, S1345, swrAA, swrAA, S1344, minJ" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3487954..3489396) /gene="ctpB" /locus_tag="BSU_35240" /old_locus_tag="BSU35240" /function="16.3: Control" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:14526016, 17557826, 27342562" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 14526016, 17557826, 27342562; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="PDZ-containing carboxyl-terminal protease processing protease [Zn(II)]" /protein_id="NP_391404.1" /db_xref="EnsemblGenomes-Gn:BSU35240" /db_xref="EnsemblGenomes-Tr:CAB15541" /db_xref="GOA:O35002" /db_xref="InterPro:IPR001478" /db_xref="InterPro:IPR002477" /db_xref="InterPro:IPR004447" /db_xref="InterPro:IPR005151" /db_xref="InterPro:IPR029045" /db_xref="InterPro:IPR036034" /db_xref="InterPro:IPR036365" /db_xref="InterPro:IPR036366" /db_xref="PDB:4C2C" /db_xref="PDB:4C2D" /db_xref="PDB:4C2E" /db_xref="PDB:4C2F" /db_xref="PDB:4C2G" /db_xref="PDB:4C2H" /db_xref="SubtiList:BG14110" /db_xref="UniProtKB/Swiss-Prot:O35002" /translation="MNQKIMAVIAAGSMLFGGAGVYAGINLLEMDKPQTAAVPATAQA DSERDKAMDKIEKAYELISNEYVEKVDREKLLEGAIQGMLSTLNDPYSVYMDKQTAKQ FSDSLDSSFEGIGAEVGMEDGKIIIVSPFKKSPAEKAGLKPNDEIISINGESMAGKDL NHAVLKIRGKKGSSVSMKIQRPGTKKQLSFRIKRAEIPLETVFASEKKVQGHSVGYIA ISTFSEHTAEDFAKALRELEKKEIEGLVIDVRGNPGGYLQSVEEILKHFVTKDQPYIQ IAERNGDKKRYFSTLTHKKAYPVNVITDKGSASASEILAGALKEAGHYDVVGDTSFGK GTVQQAVPMGDGSNIKLTLYKWLTPNGNWIHKKGIEPTIAIKQPDYFSAGPLQLKEPL KVDMNNEDVKHAQVLLKGLSFDPGREDGYFSKDMKKAVMAFQDQNKLNKTGVIDTRTA ETLNQQIEKKKSDEKNDLQLQTALKSLFVN*" gene complement(3487954..3489396) /gene="ctpB" /locus_tag="BSU_35240" /old_locus_tag="BSU35240" downshifts complement(3488043) /Source="Nicolas_upshifts" /id="D1826" /incds=1 /nref=1 /ntot=30 /MaxReadThrough="3.56833" /MaxDrop="3.1636" /score="0.562448109" /energy="-11.6" /TU="U2762" /idTUdmin="U2762" /TUdmin="-1122" /isTUend="FALSE" promotor_-10 complement(3489442..3489453) /Source="Nicolas_upshift_promotors" /id="U2762" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp="0.992007992007992" /psig="0.992007992007992" /xcortree=1138 /SigmaFactorBS="cgggacggcttttcatttgccttctttttcttctatgatTAC ATGAaatctccatcctttACATATACTATCtctaggttttggtaaagacagtctggca t" /listShort="ctpB, S1346, S1345, swrAA, swrAA, S1344, minJ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3489453) /Source="Nicolas_upshifts" /id="U2762" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp="0.992007992007992" /psig="0.992007992007992" /xcortree=1138 /SigmaFactorBS="cgggacggcttttcatttgccttctttttcttctatgatTAC ATGAaatctccatcctttACATATACTATCtctaggttttggtaaagacagtctggca t" /listShort="ctpB, S1346, S1345, swrAA, swrAA, S1344, minJ" /GFF_Attribute="listLong" promotor_-35 complement(3489468..3489474) /Source="Nicolas_upshift_promotors" /id="U2762" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp="0.992007992007992" /psig="0.992007992007992" /xcortree=1138 /SigmaFactorBS="cgggacggcttttcatttgccttctttttcttctatgatTAC ATGAaatctccatcctttACATATACTATCtctaggttttggtaaagacagtctggca t" /listShort="ctpB, S1346, S1345, swrAA, swrAA, S1344, minJ" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3489536..3490426) /gene="ftsX" /locus_tag="BSU_35250" /old_locus_tag="BSU35250" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:16352817, 17071757, 17307852, 18573177, 23855774, 23869552" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16352817, 17071757, 17307852, 18573177, 23855774, 23869552; Product type cp : cell process" /codon_start=1 /transl_table=11 /product="cell-division ABC transporter" /protein_id="NP_391405.1" /db_xref="EnsemblGenomes-Gn:BSU35250" /db_xref="EnsemblGenomes-Tr:CAB15542" /db_xref="GOA:O34876" /db_xref="InterPro:IPR003838" /db_xref="InterPro:IPR004513" /db_xref="SubtiList:BG12591" /db_xref="UniProtKB/Swiss-Prot:O34876" /translation="MIKILGRHLRESFKSLGRNTWMTFASISAVTVTLILVGVFLVIM LNLNNMATNAEKQVEIKVLIDLTADQKAQDKLQNDIKELKGIQSVTFSSKEKELDQLV DSFGDSGKSLTMKDQENPLNDAFVVKTTDPHDTPNVAKKIEKMDHVYKVTYGKEEVSR LFKVVGVSRNIGIALIIGLVFTAMFLISNTIKITIFARRKEIEIMKLVGATNWFIRWP FFLEGLLLGVFGSVIPIALVLSTYQYVIGWVVPKVQGSFVSLLPYNPFVFQVSLVLIA IGAVIGVWGSLTSIRKFLRV*" gene complement(3489536..3490426) /gene="ftsX" /locus_tag="BSU_35250" /old_locus_tag="BSU35250" downshifts complement(3489553) /Source="Nicolas_upshifts" /id="D1827" /incds=0 /nref=144 /ntot=253 /MaxReadThrough="3.3693" /MaxDrop="6.15417" /score="15.3496791" /energy="-14.6" /TU="U2763" /idTUdmin="U2763" /TUdmin="-102" /isTUend="FALSE" CDS complement(3490419..3491105) /gene="ftsE" /locus_tag="BSU_35260" /old_locus_tag="BSU35260" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:16352817, 17071757, 17307852, 18573177, 22006326, 23855774, 27167971" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16352817, 17071757, 17307852, 18573177, 22006326, 23855774, 27167971; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="cell-division signal transducer (ATP-binding protein)" /protein_id="NP_391406.1" /db_xref="EnsemblGenomes-Gn:BSU35260" /db_xref="EnsemblGenomes-Tr:CAB15543" /db_xref="GOA:O34814" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR005286" /db_xref="InterPro:IPR017871" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG12590" /db_xref="UniProtKB/Swiss-Prot:O34814" /translation="MIEMKEVYKAYPNGVKALNGISVTIHPGEFVYVVGPSGAGKSTF IKMIYREEKPTKGQILINHKDLATIKEKEIPFVRRKIGVVFQDFKLLPKLTVFENVAF ALEVIGEQPSVIKKRVLEVLDLVQLKHKARQFPDQLSGGEQQRVSIARSIVNNPDVVI ADEPTGNLDPDTSWEVMKTLEEINNRGTTVVMATHNKEIVNTMKKRVIAIEDGIIVRD ESRGEYGSYD*" gene complement(3490419..3491105) /gene="ftsE" /locus_tag="BSU_35260" /old_locus_tag="BSU35260" S_feature complement(3491106..3491238) /Source="Nicolas_S_feature" /locus_tag="new_3625508_3625640_c" /HighExp="Cold, UNK1, MG-0.2, MG 15, MG-0.1, C30, MG 25, MG 10, M9-exp, S1" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="SigA, SigA" /TUlongPSig="0.999, 0.998" /label="S1347" promotor_-10 complement(3491228..3491247) /Source="Nicolas_upshift_promotors" /id="U2763" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.9000999000999" /psig=1 /xcortree=2532 /SigmaFactorBS="atgccttgacaatatgaatgaaaagaaactgtaATAGtatta tgtctaaatTTGACGTATAATGAAGTGTAttgaaaaagggaactttcagatttttcat c" /listShort="S1347, ftsE, ftsX" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3491238) /Source="Nicolas_upshifts" /id="U2763" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.9000999000999" /psig=1 /xcortree=2532 /SigmaFactorBS="atgccttgacaatatgaatgaaaagaaactgtaATAGtatta tgtctaaatTTGACGTATAATGAAGTGTAttgaaaaagggaactttcagatttttcat c" /listShort="S1347, ftsE, ftsX" /GFF_Attribute="listLong" promotor_-35 complement(3491262..3491265) /Source="Nicolas_upshift_promotors" /id="U2763" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.9000999000999" /psig=1 /xcortree=2532 /SigmaFactorBS="atgccttgacaatatgaatgaaaagaaactgtaATAGtatta tgtctaaatTTGACGTATAATGAAGTGTAttgaaaaagggaactttcagatttttcat c" /listShort="S1347, ftsE, ftsX" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3491339..3491677) /gene="cccB" /locus_tag="BSU_35270" /old_locus_tag="BSU35270" /function="16.10: Respire" /experiment="publication(s) with functional evidences, PMID:10473570, 19222757" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10473570, 19222757; Product type f: factor" /codon_start=1 /transl_table=11 /product="cytochrome c551" /protein_id="NP_391407.1" /db_xref="EnsemblGenomes-Gn:BSU35270" /db_xref="EnsemblGenomes-Tr:CAB15544" /db_xref="GOA:O34594" /db_xref="InterPro:IPR009056" /db_xref="InterPro:IPR012218" /db_xref="InterPro:IPR036909" /db_xref="SubtiList:BG12574" /db_xref="UniProtKB/Swiss-Prot:O34594" /translation="MKSKLSILMIGFALSVLLAACGSNDAKEEKTDTGSKTEATASEG EELYQQSCVGCHGKDLEGVSGPNLQEVGGKYDEHKIESIIKNGRGNMPKGLVDDNEAA VIAKWLSEKK*" gene complement(3491339..3491677) /gene="cccB" /locus_tag="BSU_35270" /old_locus_tag="BSU35270" downshifts complement(3491340) /Source="Nicolas_upshifts" /id="D1828" /incds=0 /nref=192 /ntot=265 /MaxReadThrough="3.58546" /MaxDrop="6.88513" /score="18.0901387" /energy="-16.8" /TU="U2764" /idTUdmin="U2765" /TUdmin=3 /isTUend="TRUE" promotor_-10 complement(3491704..3491723) /Source="Nicolas_upshift_promotors" /id="U2764" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.56943056943057" /psig="0.999000999001" /xcortree=1617 /SigmaFactorBS="aattgtagcagacgcgagcgaggtgctgggcgaGGGTTTCAa acgcgcttaaacGAGGTTATAATATGGAAGAGatcgtaaaggagttgtgcttctcaac a" /listShort="cccB" /listLong="S1347, ftsE, ftsX" /label="promotor_-10" upshifts complement(3491717) /Source="Nicolas_upshifts" /id="U2764" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.56943056943057" /psig="0.999000999001" /xcortree=1617 /SigmaFactorBS="aattgtagcagacgcgagcgaggtgctgggcgaGGGTTTCAa acgcgcttaaacGAGGTTATAATATGGAAGAGatcgtaaaggagttgtgcttctcaac a" /listShort="cccB" /listLong="S1347, ftsE, ftsX" CDS complement(3491726..3492610) /gene="yvjA" /locus_tag="BSU_35280" /old_locus_tag="BSU35280" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 10473570, 15849754, 16850406; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative integral inner membrane protein" /protein_id="NP_391408.2" /db_xref="EnsemblGenomes-Gn:BSU35280" /db_xref="EnsemblGenomes-Tr:CAB15545" /db_xref="GOA:O34792" /db_xref="InterPro:IPR003740" /db_xref="InterPro:IPR019264" /db_xref="SubtiList:BG14109" /db_xref="UniProtKB/Swiss-Prot:O34792" /translation="MLSESIGRNGGYMMDVRNKTLWILRDYVYILIGAAITAVSFNVF LLPNKIAAGGVSGISTILQSYGFEAAYVQWIINIPLFIAGVILLGGKFGLKTLAGSVF LPLVVFLTRDIQPATHHELLAAIFGGVGIGIGIGIVYLGKGSTGGTALAAQIIHKYSG LSLGKCLAIIDGMIVVTAMIVFNIEQGLYAMLGVYVSSKTIDVVQVGFNRSKMALIIT KQEQAVKEAVLQKIDRGVTKISAVGGYTDDDRPILMCVVGQTEFTKLKQIVKQIDESA FVIVADASEVLGEGFKRA*" gene complement(3491726..3492610) /gene="yvjA" /locus_tag="BSU_35280" /old_locus_tag="BSU35280" promotor_-35 complement(3491737..3491744) /Source="Nicolas_upshift_promotors" /id="U2764" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.56943056943057" /psig="0.999000999001" /xcortree=1617 /SigmaFactorBS="aattgtagcagacgcgagcgaggtgctgggcgaGGGTTTCAa acgcgcttaaacGAGGTTATAATATGGAAGAGatcgtaaaggagttgtgcttctcaac a" /listShort="cccB" /listLong="S1347, ftsE, ftsX" /label="promotor_-35" promotor_-10 complement(3492598..3492617) /Source="Nicolas_upshift_promotors" /id="U2765" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.975024975024975" /psig="0.998001998001998" /xcortree=2728 /SigmaFactorBS="ttcactgctgctttagcatattaccactgtatttgggtgtTA TTTACAtctaatcagggaagGATTAAAATGCTATCGGAGAgcattggaagaaacggag g" /listShort="yvjA, cccB" /listLong="S1347, ftsE, ftsX" /label="promotor_-10" upshifts complement(3492619) /Source="Nicolas_upshifts" /id="U2765" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.975024975024975" /psig="0.998001998001998" /xcortree=2728 /SigmaFactorBS="ttcactgctgctttagcatattaccactgtatttgggtgtTA TTTACAtctaatcagggaagGATTAAAATGCTATCGGAGAgcattggaagaaacggag g" /listShort="yvjA, cccB" /listLong="S1347, ftsE, ftsX" promotor_-35 complement(3492632..3492639) /Source="Nicolas_upshift_promotors" /id="U2765" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.975024975024975" /psig="0.998001998001998" /xcortree=2728 /SigmaFactorBS="ttcactgctgctttagcatattaccactgtatttgggtgtTA TTTACAtctaatcagggaagGATTAAAATGCTATCGGAGAgcattggaagaaacggag g" /listShort="yvjA, cccB" /listLong="S1347, ftsE, ftsX" /label="promotor_-35" CDS join(complement(3493767..3493838), complement(3492737..3493765)) /gene="prfB" /locus_tag="BSU_35290" /old_locus_tag="BSU35290" /experiment="publication(s) with functional evidences, PMID:1408743, 9696765, 9882663" /ribosomal_slippage /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1408743, 9696765, 9882663; Product type f: factor" /codon_start=1 /transl_table=11 /product="peptide chain release factor 2" /protein_id="NP_391409.1" /db_xref="EnsemblGenomes-Gn:BSU35290" /db_xref="EnsemblGenomes-Tr:CAB15546" /db_xref="GOA:P28367" /db_xref="InterPro:IPR000352" /db_xref="InterPro:IPR004374" /db_xref="InterPro:IPR005139" /db_xref="InterPro:IPR020853" /db_xref="SubtiList:BG10742" /db_xref="UniProtKB/Swiss-Prot:P28367" /translation="MELSEIRAELENMASRLADFRGSLDLESKEARIAELDEQMADPE FWNDQQKAQTVINEANGLKDYVNSYKKLNESHEELQMTHDLLKEEPDTDLQLELEKEL KSLTKEFNEFELQLLLSEPYDKNNAILELHPGAGGTESQDWGSMLLRMYTRWGERRGF KVETLDYLPGDEAGIKSVTLLIKGHNAYGYLKAEKGVHRLVRISPFDSSGRRHTSFVS CEVMPEFNDEIDIDIRTEDIKVDTYRASGAGGQHVNTTDSAVRITHLPTNVVVTCQTE RSQIKNRERAMKMLKAKLYQRRIEEQQAELDEIRGEQKEIGWGSQIRSYVFHPYSMVK DHRTNTEMGNVQAVMDGDIDTFIDAYLRSKLS*" gene complement(3492737..3493838) /gene="prfB" /locus_tag="BSU_35290" /old_locus_tag="BSU35290" downshifts complement(3492753) /Source="Nicolas_upshifts" /id="D1829" /incds=0 /nref=193 /ntot=257 /MaxReadThrough="2.78016" /MaxDrop="6.41678" /score="27.1588259" /energy="-9.8" /TU="NA" /idTUdmin="U2766" /TUdmin="-2" /isTUend="TRUE" S_feature complement(3493839..3493907) /Source="Nicolas_S_feature" /locus_tag="new_3628241_3628309_c" /HighExp="Etha, Sw, Cold, BC, G150, BI, dia15, Mt0, LBGtran, LBGstat" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigH, SigEF, SigD" /TUshortPSig="0.994, 0.997, 1, 1" /TUlongSig="SigA, SigD" /TUlongPSig="0.999, 1" /label="S1348" CDS complement(3493908..3496433) /gene="secA" /locus_tag="BSU_35300" /old_locus_tag="BSU35300" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:9880811, 10074074, 10481054, 10559168, 10713435, 11021932, 12682299, 14621992, 16243836, 18923516, 23167435, 24592260, 26607006, 27336478" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9880811, 10074074, 10481054, 10559168, 10713435, 11021932, 12682299, 14621992, 16243836, 18923516, 23167435, 24592260, 26607006, 27336478; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="translocase binding subunit (ATPase)" /protein_id="NP_391410.1" /db_xref="EnsemblGenomes-Gn:BSU35300" /db_xref="EnsemblGenomes-Tr:CAB15547" /db_xref="GOA:P28366" /db_xref="InterPro:IPR000185" /db_xref="InterPro:IPR004027" /db_xref="InterPro:IPR011115" /db_xref="InterPro:IPR011116" /db_xref="InterPro:IPR011130" /db_xref="InterPro:IPR014018" /db_xref="InterPro:IPR020937" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR036266" /db_xref="InterPro:IPR036670" /db_xref="PDB:1M6N" /db_xref="PDB:1M74" /db_xref="PDB:1TF2" /db_xref="PDB:1TF5" /db_xref="PDB:2IBM" /db_xref="PDB:3DL8" /db_xref="PDB:3IQM" /db_xref="PDB:3IQY" /db_xref="PDB:3JV2" /db_xref="PDB:5EUL" /db_xref="SubtiList:BG10741" /db_xref="UniProtKB/Swiss-Prot:P28366" /translation="MLGILNKMFDPTKRTLNRYEKIANDIDAIRGDYENLSDDALKHK TIEFKERLEKGATTDDLLVEAFAVVREASRRVTGMFPFKVQLMGGVALHDGNIAEMKT GEGKTLTSTLPVYLNALTGKGVHVVTVNEYLASRDAEQMGKIFEFLGLTVGLNLNSMS KDEKREAYAADITYSTNNELGFDYLRDNMVLYKEQMVQRPLHFAVIDEVDSILIDEAR TPLIISGQAAKSTKLYVQANAFVRTLKAEKDYTYDIKTKAVQLTEEGMTKAEKAFGID NLFDVKHVALNHHINQALKAHVAMQKDVDYVVEDGQVVIVDSFTGRLMKGRRYSEGLH QAIEAKEGLEIQNESMTLATITFQNYFRMYEKLAGMTGTAKTEEEEFRNIYNMQVVTI PTNRPVVRDDRPDLIYRTMEGKFKAVAEDVAQRYMTGQPVLVGTVAVETSELISKLLK NKGIPHQVLNAKNHEREAQIIEEAGQKGAVTIATNMAGRGTDIKLGEGVKELGGLAVV GTERHESRRIDNQLRGRSGRQGDPGITQFYLSMEDELMRRFGAERTMAMLDRFGMDDS TPIQSKMVSRAVESSQKRVEGNNFDSRKQLLQYDDVLRQQREVIYKQRFEVIDSENLR EIVENMIKSSLERAIAAYTPREELPEEWKLDGLVDLINTTYLDEGALEKSDIFGKEPD EMLELIMDRIITKYNEKEEQFGKEQMREFEKVIVLRAVDSKWMDHIDAMDQLRQGIHL RAYAQTNPLREYQMEGFAMFEHMIESIEDEVAKFVMKAEIENNLEREEVVQGQTTAHQ PQEGDDNKKAKKAPVRKVVDIGRNAPCHCGSGKKYKNCCGRTE*" gene complement(3493908..3496433) /gene="secA" /locus_tag="BSU_35300" /old_locus_tag="BSU35300" S_feature complement(3496434..3496514) /Source="Nicolas_S_feature" /locus_tag="new_3630836_3630916_c" /HighExp="Etha, M9-stat, T0.30H, B60, dia5, Cold, dia15, Lbexp, Salt, T4.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigH, SigEF, SigD" /TUshortPSig="0.994, 0.997, 1, 1" /TUlongSig="SigA, SigD" /TUlongPSig="0.999, 1" /label="S1349" misc_feature complement(3496504..3496523) /Source="Nicolas_upshift_promotors" /id="U2766" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.69030969030969" /psig="0.994005994005994" /xcortree=106 /SigmaFactorBS="cggaaggtttttgtttttcttatttgcaaattctttggaaat aacaaaaggTATGATATGATAATGAGAGGtatacatggactagtaaattatttataca t" /listShort="S1349, secA, S1348, prfB" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(3496514) /Source="Nicolas_upshifts" /id="U2766" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.69030969030969" /psig="0.994005994005994" /xcortree=106 /SigmaFactorBS="cggaaggtttttgtttttcttatttgcaaattctttggaaat aacaaaaggTATGATATGATAATGAGAGGtatacatggactagtaaattatttataca t" /listShort="S1349, secA, S1348, prfB" /GFF_Attribute="listLong" CDS complement(3496601..3497170) /gene="hpf" /locus_tag="BSU_35310" /old_locus_tag="BSU35310" /function="16.6: Maintain" /function="16.3: Control" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:11948165, 16324148, 17274076, 17277072, 19747895, 22720735, 22950019, 28468753" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11948165, 16324148, 17274076, 17277072, 19747895, 22720735, 22950019, 28468753; Product type f: factor" /codon_start=1 /transl_table=11 /product="ribosome-associated sigma 54 modulation protein;ribosome dimerisation factor" /protein_id="NP_391411.1" /db_xref="EnsemblGenomes-Gn:BSU35310" /db_xref="EnsemblGenomes-Tr:CAB15548" /db_xref="GOA:P28368" /db_xref="InterPro:IPR003489" /db_xref="InterPro:IPR032528" /db_xref="InterPro:IPR034694" /db_xref="InterPro:IPR036567" /db_xref="PDB:5NJT" /db_xref="SubtiList:BG10740" /db_xref="UniProtKB/Swiss-Prot:P28368" /translation="MNYNIRGENIEVTPALKDHVERKIGKLERYFDHSVDADVNVNLK FYNDKESKVEVTIPMTDLALRSEVHNEDMYNAIDLATNKLERQIRKHKTKVNRKFREQ GSPKYLLANGLGSDTDIAVQDDIEEEESLDIVRQKRFNLKPMDSEEAILQMNMLGHNF FVFTNAETNLTNVVYRRNDGKYGLIEPTE*" gene complement(3496601..3497170) /gene="hpf" /locus_tag="BSU_35310" /old_locus_tag="BSU35310" downshifts complement(3496609) /Source="Nicolas_upshifts" /id="D1830" /incds=0 /nref=78 /ntot=209 /MaxReadThrough="8.66806" /MaxDrop="4.7023" /score="29.9030506" /energy="-12.2" /TU="U2768,U2769,U2770,U2773" /idTUdmin="U2773" /TUdmin="-74" /isTUend="FALSE" promotor_-35 3497137..3497143 /Source="Nicolas_upshift_promotors" /id="U2767" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.365634365634366" /psig="0.829170829170829" /xcortree=289 /SigmaFactorBS="ttcctctcgacatgatcctttaacgcgggtgtcaCTTCAATa ttttctcctctGATGTTATAGTTCATCAAAGaacgcctcccttttattaaggatatgt a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3497156..3497175 /Source="Nicolas_upshift_promotors" /id="U2767" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.365634365634366" /psig="0.829170829170829" /xcortree=289 /SigmaFactorBS="ttcctctcgacatgatcctttaacgcgggtgtcaCTTCAATa ttttctcctctGATGTTATAGTTCATCAAAGaacgcctcccttttattaaggatatgt a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3497163 /Source="Nicolas_upshifts" /id="U2767" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.365634365634366" /psig="0.829170829170829" /xcortree=289 /SigmaFactorBS="ttcctctcgacatgatcctttaacgcgggtgtcaCTTCAATa ttttctcctctGATGTTATAGTTCATCAAAGaacgcctcccttttattaaggatatgt a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 complement(3497197..3497215) /Source="Nicolas_upshift_promotors" /id="U2768" /multdbtbs="SigB,SigH" /comp="M1" /sig="SigH" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=499 /SigmaFactorBS="actgaattttcacaaaagatttatgtttcaGCAGGAATTgta aagggtaaAAGAGAAATAGATACATATccttaataaaagggaggcgttctttgatgaa c" /listShort="yvyD, S1349, secA, S1348, prfB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3497205) /Source="Nicolas_upshifts" /id="U2768" /multdbtbs="SigB,SigH" /comp="M1" /sig="SigH" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=499 /SigmaFactorBS="actgaattttcacaaaagatttatgtttcaGCAGGAATTgta aagggtaaAAGAGAAATAGATACATATccttaataaaagggaggcgttctttgatgaa c" /listShort="yvyD, S1349, secA, S1348, prfB" /GFF_Attribute="listLong" S_feature complement(3497207..3497327) /Source="Nicolas_S_feature" /locus_tag="new_3631609_3631729_c" /HighExp="C30, M0t90, S4, Lbstat, S5, M40t90, Glucon, Gly, C90, GM 60" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigEF, SigD, SigD" /TUshortPSig="1, 1, 1" /TUlongSig="SigA" /TUlongPSig="0.999" /label="S1350" promotor_-35 complement(3497227..3497235) /Source="Nicolas_upshift_promotors" /id="U2768" /multdbtbs="SigB,SigH" /comp="M1" /sig="SigH" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=499 /SigmaFactorBS="actgaattttcacaaaagatttatgtttcaGCAGGAATTgta aagggtaaAAGAGAAATAGATACATATccttaataaaagggaggcgttctttgatgaa c" /listShort="yvyD, S1349, secA, S1348, prfB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(3497311..3497329) /Source="Nicolas_upshift_promotors" /id="U2769" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1221 /SigmaFactorBS="tgtatggaaccctttttaatcaattaggcgtgtgtgaGGTAT TtgtttcgttcaatcaGCATATACATATACCTCCGaaccgccaataacagagcaaata c" /listShort="S1350, yvyD, S1349, secA, S1348, prfB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3497327) /Source="Nicolas_upshifts" /id="U2769" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1221 /SigmaFactorBS="tgtatggaaccctttttaatcaattaggcgtgtgtgaGGTAT TtgtttcgttcaatcaGCATATACATATACCTCCGaaccgccaataacagagcaaata c" /listShort="S1350, yvyD, S1349, secA, S1348, prfB" /GFF_Attribute="listLong" promotor_-35 complement(3497345..3497350) /Source="Nicolas_upshift_promotors" /id="U2769" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1221 /SigmaFactorBS="tgtatggaaccctttttaatcaattaggcgtgtgtgaGGTAT TtgtttcgttcaatcaGCATATACATATACCTCCGaaccgccaataacagagcaaata c" /listShort="S1350, yvyD, S1349, secA, S1348, prfB" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3497361..3497738) /gene="yvzG" /locus_tag="BSU_35319" /old_locus_tag="BSU35319" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="YP_003097791.1" /db_xref="EnsemblGenomes-Gn:BSU35319" /db_xref="EnsemblGenomes-Tr:CAX52698" /db_xref="UniProtKB/Swiss-Prot:C0H3R9" /translation="MKSIEDYTLLSAYYHLLFTIEEGLCYLIEAEENLSKTEGDRIYQ DLIQAFFYLDSTHSTLLFIMDSRCAEICVKAFDQIFAEFDQLVSFSFPSHEFCEYLKE HFLIHYRKWMLSIHQCMEPFLIN*" gene complement(3497361..3497738) /gene="yvzG" /locus_tag="BSU_35319" /old_locus_tag="BSU35319" CDS complement(3497748..3498089) /gene="fliT" /locus_tag="BSU_35320" /old_locus_tag="BSU35320" /function="16.3: Control" /function="16.5: Explore" /function="16.13: Shape" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 12354229, 16952964; Product type s: structure" /codon_start=1 /transl_table=11 /product="flagellar assembly protein FliT involved in control of flagella expression" /protein_id="NP_391412.1" /db_xref="EnsemblGenomes-Gn:BSU35320" /db_xref="EnsemblGenomes-Tr:CAB15549" /db_xref="GOA:P39740" /db_xref="SubtiList:BG10923" /db_xref="UniProtKB/Swiss-Prot:P39740" /translation="MNNIDQLYTETKSMLSHIQNTPESDELLKQIEDFVATRSELIQE ISLPLSEEERKQMKLILTWDQLIVKEMERLKQSIATELQQMKRKRVMHTTYLNPYNNI TIDGTYYDKRK*" gene complement(3497748..3498089) /gene="fliT" /locus_tag="BSU_35320" /old_locus_tag="BSU35320" CDS complement(3498086..3498487) /gene="fliS" /locus_tag="BSU_35330" /old_locus_tag="BSU35330" /function="16.5: Explore" /function="16.13: Shape" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 12354229, 16806204, 16936039, 20534509, 23144244, 23874669; Product type s : structure" /codon_start=1 /transl_table=11 /product="flagellar assembly protein FliS" /protein_id="NP_391413.1" /db_xref="EnsemblGenomes-Gn:BSU35330" /db_xref="EnsemblGenomes-Tr:CAB15550" /db_xref="GOA:P39739" /db_xref="InterPro:IPR003713" /db_xref="InterPro:IPR036584" /db_xref="PDB:1VH6" /db_xref="SubtiList:BG10922" /db_xref="UniProtKB/Swiss-Prot:P39739" /translation="MAIQNPYTAYQQNSVNTATPGELTLMLYNGCLKFIRLAAQAIEN DDMERKNENLIKAQNIIQELNFTLNRNIELSASMGAMYDYMYRRLVQANIKNDTGMLA EVEGYVTDFRDAWKQAIQSERKDRHGSGGIA*" gene complement(3498086..3498487) /gene="fliS" /locus_tag="BSU_35330" /old_locus_tag="BSU35330" CDS complement(3498509..3500005) /gene="fliD" /locus_tag="BSU_35340" /old_locus_tag="BSU35340" /function="16.5: Explore" /function="16.13: Shape" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 9648743, 12354229, 24296669, 25355936; Product type s: structure" /codon_start=1 /transl_table=11 /product="flagellar hook-associated capping protein 2 (HAP2)" /protein_id="NP_391414.1" /db_xref="EnsemblGenomes-Gn:BSU35340" /db_xref="EnsemblGenomes-Tr:CAB15551" /db_xref="GOA:P39738" /db_xref="InterPro:IPR003481" /db_xref="InterPro:IPR010809" /db_xref="InterPro:IPR010810" /db_xref="SubtiList:BG10921" /db_xref="UniProtKB/Swiss-Prot:P39738" /translation="MVTRITGLASGMDIDDIVSKLMQTERAPLDKLTQKKQTLEWQRD SYREVNSKIKELQDYMSKNTLTYPSTYQSKTVTSSNESVLTATGSVSAPNSSSTVEVA SLATAATYKANNYTGYTQGDYNLAFNVVAPGETTAKTVNISVTSADTIDNVISKLNSS DLGVSAFKDKIWNGTEYVETIAFSSKATGAGGSIQAADSATADFMSGQLGFSLDADNK LTAYKEGTNAKVTINGFEMEKLTNNFTVNGVTYSIKNTTAATGPVTTSVSTDVDGIYN QIKEFVDKYNELVDSLNEKLKEEKYRDYTPLTSEQKEAMSDKEVELWEEKAKSGLLRN DSSISTGTNQMRTDFYTQVNADGKTYQLTEFGITTSSAYQLRGHLEINEEKLKAKIAE DPQGVANLFTSGTNDSNYSDKGIMKRITNTLRSTVKSIEAKAGNSTMGASSYSIGKNL NSISTEITDMQDRLNTIENRYYSKFSAMDSAIQKMNEQASYLSQLLVQ*" gene complement(3498509..3500005) /gene="fliD" /locus_tag="BSU_35340" /old_locus_tag="BSU35340" CDS complement(3500023..3500352) /gene="yvyC" /locus_tag="BSU_35350" /old_locus_tag="BSU35350" /function="16.13: Shape" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 12354229, 19455708; Product type s: structure" /codon_start=1 /transl_table=11 /product="putative flagellar protein of unknown function" /protein_id="NP_391415.1" /db_xref="EnsemblGenomes-Gn:BSU35350" /db_xref="EnsemblGenomes-Tr:CAB15552" /db_xref="InterPro:IPR005186" /db_xref="InterPro:IPR035924" /db_xref="PDB:2HC5" /db_xref="SubtiList:BG10920" /db_xref="UniProtKB/Swiss-Prot:P39737" /translation="MNIERLTTLQPVWDRYDTQIHNQKDNDNEVPVHQVSYTNLAEMV GEMNKLLEPSQVHLKFELHDKLNEYYVKVIEDSTNEVIREIPPKRWLDFYAAMTEFLG LFVDEKK*" gene complement(3500023..3500352) /gene="yvyC" /locus_tag="BSU_35350" /old_locus_tag="BSU35350" downshifts 3500349 /Source="Nicolas_upshifts" /id="D1831" /incds=0 /nref=33 /ntot=140 /MaxReadThrough="2.74277" /MaxDrop="4.24086" /score="8.30527041" /energy="-10.1" /TU="NA" /idTUdmin="U2774" /TUdmin="-3062" /isTUend="FALSE" promotor_-10 complement(3500374..3500392) /Source="Nicolas_upshift_promotors" /id="U2770" /multdbtbs="SigD" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2807 /SigmaFactorBS="agaaatctaaaacagaagatttttttccaaaaatatGTGTAA TCttatctcgacttaGTCGATATAAACGATAGATtggggcataggggatgatcaattg a" /listShort="yvyC, fliD, fliS, fliT, yvzG, S1350, yvyD, S1349, secA, S1348, prfB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3500389) /Source="Nicolas_upshifts" /id="U2770" /multdbtbs="SigD" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2807 /SigmaFactorBS="agaaatctaaaacagaagatttttttccaaaaatatGTGTAA TCttatctcgacttaGTCGATATAAACGATAGATtggggcataggggatgatcaattg a" /listShort="yvyC, fliD, fliS, fliT, yvzG, S1350, yvyD, S1349, secA, S1348, prfB" /GFF_Attribute="listLong" S_feature complement(3500391..3500495) /Source="Nicolas_S_feature" /locus_tag="new_3634793_3634897_c" /HighExp="Lbstat, Cold, Gly, S0, Glu, Pyr, M/G, M0t90, C30, Fru" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigD" /TUshortPSig="0.999, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S1351" promotor_-35 complement(3500406..3500413) /Source="Nicolas_upshift_promotors" /id="U2770" /multdbtbs="SigD" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2807 /SigmaFactorBS="agaaatctaaaacagaagatttttttccaaaaatatGTGTAA TCttatctcgacttaGTCGATATAAACGATAGATtggggcataggggatgatcaattg a" /listShort="yvyC, fliD, fliS, fliT, yvzG, S1350, yvyD, S1349, secA, S1348, prfB" /GFF_Attribute="listLong" /label="promotor_-35" misc_feature complement(3500484..3500503) /Source="Nicolas_upshift_promotors" /id="U2771" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.498501498501498" /psig="0.999000999001" /xcortree=2693 /SigmaFactorBS="tcttttaatttaaatttctatctcctaatcattcctcatcct gtcactaactCATGATATAATAACCGGATTctccactaactttttataaatgtatttc c" /listShort="S1351, yvyC, fliD, fliS, fliT, yvzG" /listLong="S1350, yvyD, S1349, secA, S1348, prfB" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(3500495) /Source="Nicolas_upshifts" /id="U2771" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.498501498501498" /psig="0.999000999001" /xcortree=2693 /SigmaFactorBS="tcttttaatttaaatttctatctcctaatcattcctcatcct gtcactaactCATGATATAATAACCGGATTctccactaactttttataaatgtatttc c" /listShort="S1351, yvyC, fliD, fliS, fliT, yvzG" /listLong="S1350, yvyD, S1349, secA, S1348, prfB" CDS complement(3500585..3501499) /gene="hag" /locus_tag="BSU_35360" /old_locus_tag="BSU35360" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:8045886, 9648743, 12730172, 14762011, 15342569, 22720735, 25355936, 28800172, 29124898" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8045886, 9648743, 12730172, 14762011, 15342569, 22720735, 25355936, 28800172, 29124898; Product type s: structure" /codon_start=1 /transl_table=11 /product="flagellin protein" /protein_id="NP_391416.1" /db_xref="EnsemblGenomes-Gn:BSU35360" /db_xref="EnsemblGenomes-Tr:CAB15553" /db_xref="GOA:P02968" /db_xref="InterPro:IPR001029" /db_xref="InterPro:IPR001492" /db_xref="SubtiList:BG10655" /db_xref="UniProtKB/Swiss-Prot:P02968" /translation="MRINHNIAALNTLNRLSSNNSASQKNMEKLSSGLRINRAGDDAA GLAISEKMRGQIRGLEMASKNSQDGISLIQTAEGALTETHAILQRVRELVVQAGNTGT QDKATDLQSIQDEISALTDEIDGISNRTEFNGKKLLDGTYKVDTATPANQKNLVFQIG ANATQQISVNIEDMGADALGIKEADGSIAALHSVNDLDVTKFADNAADTADIGFDAQL KVVDEAINQVSSQRAKLGAVQNRLEHTINNLSASGENLTAAESRIRDVDMAKEMSEFT KNNILSQASQAMLAQANQQPQNVLQLLR*" gene complement(3500585..3501499) /gene="hag" /locus_tag="BSU_35360" /old_locus_tag="BSU35360" downshifts complement(3500605) /Source="Nicolas_upshifts" /id="D1832" /incds=0 /nref=165 /ntot=233 /MaxReadThrough="5.58531" /MaxDrop="7.10921" /score="11.6997504" /energy="-13.1" /TU="U2773" /idTUdmin="U2775" /TUdmin=1078 /isTUend="FALSE" S_feature complement(3501500..3501608) /Source="Nicolas_S_feature" /locus_tag="new_3635902_3636010_c" /HighExp="T2.0H, Glucon, M0t90, T2.30H, GM 15, T-0.40H, GM 10, T1.0H, T-1.10H, C90" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigD" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1352" promotor_-35 3501566..3501567 /Source="Nicolas_upshift_promotors" /id="U2772" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.997002997002997" /psig=0 /xcortree=717 /SigmaFactorBS="gttaaggcacgtccttgtgcccttattttgtaactggctgaG TcttttgcgCCTCCTCCCGGCTACatcattaatatcggattgtctctgattttgttaa t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3501576..3501590 /Source="Nicolas_upshift_promotors" /id="U2772" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.997002997002997" /psig=0 /xcortree=717 /SigmaFactorBS="gttaaggcacgtccttgtgcccttattttgtaactggctgaG TcttttgcgCCTCCTCCCGGCTACatcattaatatcggattgtctctgattttgttaa t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3501585 /Source="Nicolas_upshifts" /id="U2772" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.997002997002997" /psig=0 /xcortree=717 /SigmaFactorBS="gttaaggcacgtccttgtgcccttattttgtaactggctgaG TcttttgcgCCTCCTCCCGGCTACatcattaatatcggattgtctctgattttgttaa t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 complement(3501587..3501605) /Source="Nicolas_upshift_promotors" /id="U2773" /multdbtbs="SigD" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2833 /SigmaFactorBS="cgcattatcctcacaaaaaaagtgaggatttttttatttttg tATTAACAAaatcagagacaaTCCGATATTAATGATGTAGccgggaggaggcgcaaaa g" /listShort="S1352, hag, S1351, yvyC, fliD, fliS, fliT, yvzG, S1350, yvyD" /listLong="S1349, secA, S1348, prfB" /label="promotor_-10" upshifts complement(3501608) /Source="Nicolas_upshifts" /id="U2773" /multdbtbs="SigD" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2833 /SigmaFactorBS="cgcattatcctcacaaaaaaagtgaggatttttttatttttg tATTAACAAaatcagagacaaTCCGATATTAATGATGTAGccgggaggaggcgcaaaa g" /listShort="S1352, hag, S1351, yvyC, fliD, fliS, fliT, yvzG, S1350, yvyD" /listLong="S1349, secA, S1348, prfB" promotor_-35 complement(3501618..3501625) /Source="Nicolas_upshift_promotors" /id="U2773" /multdbtbs="SigD" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2833 /SigmaFactorBS="cgcattatcctcacaaaaaaagtgaggatttttttatttttg tATTAACAAaatcagagacaaTCCGATATTAATGATGTAGccgggaggaggcgcaaaa g" /listShort="S1352, hag, S1351, yvyC, fliD, fliS, fliT, yvzG, S1350, yvyD" /listLong="S1349, secA, S1348, prfB" /label="promotor_-35" CDS complement(3501644..3501868) /gene="csrA" /locus_tag="BSU_35370" /old_locus_tag="BSU35370" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:8982093, 17555441, 21895793, 23144244, 27516547" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8982093, 17555441, 21895793, 23144244, 27516547; Product type r: regulator" /codon_start=1 /transl_table=11 /product="carbon storage regulator" /protein_id="NP_391417.1" /db_xref="EnsemblGenomes-Gn:BSU35370" /db_xref="EnsemblGenomes-Tr:CAB15554" /db_xref="GOA:P33911" /db_xref="InterPro:IPR003751" /db_xref="InterPro:IPR036107" /db_xref="PDB:1T3O" /db_xref="SubtiList:BG10654" /db_xref="UniProtKB/Swiss-Prot:P33911" /translation="MLVLSRKINEAIQIGADIEVKVIAVEGDQVKLGIDAPKHIDIHR KEIYLTIQEENNRAAALSSDVISALSSQKK*" gene complement(3501644..3501868) /gene="csrA" /locus_tag="BSU_35370" /old_locus_tag="BSU35370" downshifts complement(3501683) /Source="Nicolas_upshifts" /id="D1833" /incds=0 /nref=22 /ntot=171 /MaxReadThrough="2.28652" /MaxDrop="3.46262" /score="31.5820557" /energy="-9.2" /TU="NA" /idTUdmin="U2775" /TUdmin=0 /isTUend="TRUE" CDS complement(3501862..3502293) /gene="fliW" /locus_tag="BSU_35380" /old_locus_tag="BSU35380" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:15033535, 16936039, 21895793, 27516547" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15033535, 16936039, 21895793, 27516547; Product type f: factor" /codon_start=1 /transl_table=11 /product="assembly factor of the flagellum" /protein_id="NP_391418.1" /db_xref="EnsemblGenomes-Gn:BSU35380" /db_xref="EnsemblGenomes-Tr:CAB15555" /db_xref="GOA:P96503" /db_xref="InterPro:IPR003775" /db_xref="InterPro:IPR024046" /db_xref="SubtiList:BG12451" /db_xref="UniProtKB/Swiss-Prot:P96503" /translation="MIIHTKYHGQMNIKEEQIILFESGIPGFLEEKQFVILPLSEDSP FVALQSVTSENLAFIVVSPFIFFKNYEFDLDESTAELLDIDNIQDVEVMTILTMAEPF EKSTANLLAPIIVNRKNMMAKQVVLHDSSYTTKHPIGGESC*" gene complement(3501862..3502293) /gene="fliW" /locus_tag="BSU_35380" /old_locus_tag="BSU35380" CDS complement(3502314..3502889) /gene="yviE" /locus_tag="BSU_35390" /old_locus_tag="BSU35390" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 15033535" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_391419.1" /db_xref="EnsemblGenomes-Gn:BSU35390" /db_xref="EnsemblGenomes-Tr:CAB15556" /db_xref="SubtiList:BG12450" /db_xref="UniProtKB/Swiss-Prot:P96502" /translation="MQIPRLIMHSVQGKIGLTTTPASLKMEQPQADLEIEQPSAEMEI SVTPGKLTIDQTQAWEELDRKHVFKRIEEAAQQGHEDVMEGIARTAEEGDELMKIENK GNPIASQARRNSEMHQIQLGENYAPSLSRVKIQYTPSQLDVQITPRKPVIQAEPHKPI VEYTPGNVKVDMLQYPDLNIDVEYPKESPEK*" gene complement(3502314..3502889) /gene="yviE" /locus_tag="BSU_35390" /old_locus_tag="BSU35390" CDS complement(3502936..3503832) /gene="flgL" /locus_tag="BSU_35400" /old_locus_tag="BSU35400" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 2407720, 15033535, 17438286, 23874669, 24296669, 24706744; Product type s : structure" /codon_start=1 /transl_table=11 /product="flagellar hook-filament junction protein" /protein_id="NP_391420.1" /db_xref="EnsemblGenomes-Gn:BSU35400" /db_xref="EnsemblGenomes-Tr:CAB15557" /db_xref="GOA:P96501" /db_xref="InterPro:IPR001029" /db_xref="InterPro:IPR013384" /db_xref="SubtiList:BG11936" /db_xref="UniProtKB/Swiss-Prot:P96501" /translation="MRVTQGMIQQNSLRYIGSSYSKLDKLQSQISSGKKISKASDDPV VAMKSLKYNTQLSQVQQYKSNASQAFTWLENTETNITEGIDILSKVRELAVEAQNDTN GEPERQAIGVEVKQLKEQLLNIANTQVNGRYIFNGTNSDKPPVTDNGDGTYTISDTAD VVVNISNNMSLKVNSDPKSAFGGTSESGQNVFEMLDSFEKALNSGSLDGMDSVLNDID HFSDGMSAERSDLGARYNRLELVNTRLSAQEETATKVLSDNEDVELEEVITEFIAQQS VHRATLAVNAQIVQPTLIDFLK*" gene complement(3502936..3503832) /gene="flgL" /locus_tag="BSU_35400" /old_locus_tag="BSU35400" downshifts complement(3502959) /Source="Nicolas_upshifts" /id="D1834" /incds=0 /nref=112 /ntot=251 /MaxReadThrough="5.50861" /MaxDrop="3.8234" /score="0.376587888" /energy="-4.8" /TU="U2775,U2776,U2777" /idTUdmin="U2777" /TUdmin="-1254" /isTUend="FALSE" misc_feature 3503248..3503251 /Source="Nicolas_upshift_promotors" /id="U2774" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.97902097902098" /psig="0.000999000999001" /xcortree=54 /SigmaFactorBS="actgtccatgccatctagcgaaccagaatttagtgctttctc aaaagaatcAAGCatttcaaatacattctgcccgctttcagaagtgcctccaaaagct g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 3503257 /Source="Nicolas_upshifts" /id="U2774" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.97902097902098" /psig="0.000999000999001" /xcortree=54 /SigmaFactorBS="actgtccatgccatctagcgaaccagaatttagtgctttctc aaaagaatcAAGCatttcaaatacattctgcccgctttcagaagtgcctccaaaagct g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" CDS complement(3503843..3505366) /gene="flgK" /locus_tag="BSU_35410" /old_locus_tag="BSU35410" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 2407720, 15033535, 17438286, 23874669, 24296669, 24706744; Product type s : structure" /codon_start=1 /transl_table=11 /product="flagellar hook-filament junction" /protein_id="NP_391421.1" /db_xref="EnsemblGenomes-Gn:BSU35410" /db_xref="EnsemblGenomes-Tr:CAB15558" /db_xref="GOA:P39810" /db_xref="InterPro:IPR001444" /db_xref="InterPro:IPR002371" /db_xref="InterPro:IPR010930" /db_xref="InterPro:IPR019776" /db_xref="SubtiList:BG10401" /db_xref="UniProtKB/Swiss-Prot:P39810" /translation="MTSTFMGLETARRALSAQQAALSTTANNVANANTDGYTRQRVSL EATDYFPAVSKNAEKTAGQMGTGVQGKSVERIRDIFLDYQYRLQNNSAGYYDTKAKAL SQMEGVLNETDDSGLNSVLNSFWNSLQELSNNTNEESARSVVARKGQAVAETFNYISE SLTNVQSNLKAELNTTVLDVNSLLSQLNSLNKQIAQVEPVGLLPNGLYDQRDLLIDKL SSMVDIKVSYNKSGGNALASAEGTVSIEILDKNKQSLGTVLDGKNYEVSELAANYDNE TGLVSSISIGDTAVQAESFSSKGSLLGFIESYGYITADGQEKGVYPEMLSDLDNMALE FAKAFNEVHRNGVTKSGEQGGDFFDFTGGETEPAKGAAGKIKVADSIIDSKGANIAFS LTGAANDNANATKLANVLTGKITINGKETSVLDYYAGLIGELGIEAQEANRLASNTET QLNDADINRQQMSAVSLDEEMTNMIQFQHAYNAAARMVTLQDELLDKVINGMGVGGR* " gene complement(3503843..3505366) /gene="flgK" /locus_tag="BSU_35410" /old_locus_tag="BSU35410" CDS complement(3505385..3505867) /gene="flgN" /locus_tag="BSU_35420" /old_locus_tag="BSU35420" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:24706744" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 24706744; Product type f: factor" /codon_start=1 /transl_table=11 /product="factor required for flagellar based motility" /protein_id="NP_391422.1" /db_xref="EnsemblGenomes-Gn:BSU35420" /db_xref="EnsemblGenomes-Tr:CAB15559" /db_xref="GOA:P39808" /db_xref="InterPro:IPR007809" /db_xref="InterPro:IPR036679" /db_xref="SubtiList:BG10400" /db_xref="UniProtKB/Swiss-Prot:P39808" /translation="MSAKAIIEQLKRLCVLHEHLLTLSEEKTEALKAGKTKELSNILT KEQKYIQAITQTEDDRIKTTSAFLGYSENNTISACIAKTSGSEKEELEQLYESLSQVL GRLKKVNEMNRQLTRDALQFISISYDMLVPKENNFNYSKSIKAELPKSSKMKLFDSKA *" gene complement(3505385..3505867) /gene="flgN" /locus_tag="BSU_35420" /old_locus_tag="BSU35420" CDS complement(3505883..3506149) /gene="flgM" /locus_tag="BSU_35430" /old_locus_tag="BSU35430" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:10207036, 10322161, 14762011, 16673084, 21736639, 22720735, 25313396" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10207036, 10322161, 14762011, 16673084, 21736639, 22720735, 25313396; Product type r: regulator" /codon_start=1 /transl_table=11 /product="anti-sigma factor repressor of sigma(D)-dependent transcription" /protein_id="NP_391423.1" /db_xref="EnsemblGenomes-Gn:BSU35430" /db_xref="EnsemblGenomes-Tr:CAB15560" /db_xref="GOA:P39809" /db_xref="InterPro:IPR007412" /db_xref="InterPro:IPR031316" /db_xref="InterPro:IPR035890" /db_xref="SubtiList:BG10399" /db_xref="UniProtKB/Swiss-Prot:P39809" /translation="MKINQFGTQSVNPYQKNYDKQAVQKTVAQPQDKIEISSQAKEMQ HASDAVTGSRQEKIAQLKAQIENGSYKVDANHIAKNMINFYKKQ*" gene complement(3505883..3506149) /gene="flgM" /locus_tag="BSU_35430" /old_locus_tag="BSU35430" S_feature complement(3506150..3506229) /Source="Nicolas_S_feature" /locus_tag="new_3640552_3640631_c" /HighExp="T0.30H, Cold, C90, T-5.40H, T-4.40H, GM 150, T-2.40H, GM 45, S2, GM 90" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigD, SigA, SigA" /TUshortPSig="1, 1, 0.997" /TUlongSig="NA" /TUlongPSig="NA" /label="S1353" CDS complement(3506230..3506649) /gene="yvyF" /locus_tag="BSU_35440" /old_locus_tag="BSU35440" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 9696775; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative transcriptional regulator of flagella formation" /protein_id="NP_391424.1" /db_xref="EnsemblGenomes-Gn:BSU35440" /db_xref="EnsemblGenomes-Tr:CAB15561" /db_xref="GOA:P39807" /db_xref="InterPro:IPR022258" /db_xref="SubtiList:BG10398" /db_xref="UniProtKB/Swiss-Prot:P39807" /translation="MGELANCPKCNALFLKTKLQTVCQACIKEEEKSFETVYKFLRKQ ENRQSTLSRITEETGVEEELILKFIRQKRIQITHLPNLAYPCERCGTSIREGKFCKAC QSDIKDQMDHLNHEDALKIEKENSKKDTYYAYNTKNS*" gene complement(3506230..3506649) /gene="yvyF" /locus_tag="BSU_35440" /old_locus_tag="BSU35440" promotor_-10 complement(3506688..3506706) /Source="Nicolas_upshift_promotors" /id="U2775" /multdbtbs="SigD" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2812 /SigmaFactorBS="cgcttcagtgtcatcttttaccttgatcagaaGCTAAATGat tctgtttttatGCCGATATAATCACTAGAAattgacacaggcatattatctaataagg a" /listShort="yvyF, S1353, flgM, yvyG, flgK, flgL, yviE, fliW, csrA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3506699) /Source="Nicolas_upshifts" /id="U2775" /multdbtbs="SigD" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2812 /SigmaFactorBS="cgcttcagtgtcatcttttaccttgatcagaaGCTAAATGat tctgtttttatGCCGATATAATCACTAGAAattgacacaggcatattatctaataagg a" /listShort="yvyF, S1353, flgM, yvyG, flgK, flgL, yviE, fliW, csrA" /GFF_Attribute="listLong" promotor_-35 complement(3506720..3506727) /Source="Nicolas_upshift_promotors" /id="U2775" /multdbtbs="SigD" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2812 /SigmaFactorBS="cgcttcagtgtcatcttttaccttgatcagaaGCTAAATGat tctgtttttatGCCGATATAATCACTAGAAattgacacaggcatattatctaataagg a" /listShort="yvyF, S1353, flgM, yvyG, flgK, flgL, yviE, fliW, csrA" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3506723..3507445) /gene="comFC" /locus_tag="BSU_35450" /old_locus_tag="BSU35450" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:8045879, 8412657, 16009133, 28618091" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8045879, 8412657, 16009133, 28618091; Product type t: transporter" /codon_start=1 /transl_table=11 /product="component of the DNA transport apparatus" /protein_id="NP_391425.2" /db_xref="EnsemblGenomes-Gn:BSU35450" /db_xref="EnsemblGenomes-Tr:CAB15562" /db_xref="GOA:P39147" /db_xref="InterPro:IPR000836" /db_xref="InterPro:IPR005222" /db_xref="InterPro:IPR029057" /db_xref="SubtiList:BG10397" /db_xref="UniProtKB/Swiss-Prot:P39147" /translation="MSNEAGGGIHKLICLLCDSQFSQDVTWRALFLLKPDEKVCYSCR SKLKKITGHICPLCGRPQSVHAVCRDCEVWRTRIRDSLLLRQNRSVYTYNDMMKETLS RFKFRGDAEIINAFKSDFSSTFSKVYPDKHFVLVPIPLSKEREEERGFNQAHLLAECL DRPSHHPLIRLNNEKQSKKKKTERLLSECIFDTKNNSAEGMNIILIDDLYTTGATLHF AARCLLEKGKAASVSSFTLIRS*" gene complement(3506723..3507445) /gene="comFC" /locus_tag="BSU_35450" /old_locus_tag="BSU35450" CDS complement(3507409..3507705) /gene="comFB" /locus_tag="BSU_35460" /old_locus_tag="BSU35460" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:8045879, 8412657, 16009133, 25423369" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8045879, 8412657, 16009133, 25423369; Product type r: regulator" /codon_start=1 /transl_table=11 /product="regulator of competence, pole located" /protein_id="NP_391426.1" /db_xref="EnsemblGenomes-Gn:BSU35460" /db_xref="EnsemblGenomes-Tr:CAB15563" /db_xref="GOA:P39146" /db_xref="InterPro:IPR019657" /db_xref="PDB:4WAI" /db_xref="SubtiList:BG10396" /db_xref="UniProtKB/Swiss-Prot:P39146" /translation="MLVNSKEIVMKELLDRYMDQLHMACTCQVCQNDVLALSLNKVSP SYVTDFKKIAYTKAELVDKQKNTAMLVILAESAAVVSESPSDLCQTKQEEAFIN*" gene complement(3507409..3507705) /gene="comFB" /locus_tag="BSU_35460" /old_locus_tag="BSU35460" promotor_-10 complement(3507731..3507750) /Source="Nicolas_upshift_promotors" /id="U2776" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.797202797202797" /psig=1 /xcortree=2253 /SigmaFactorBS="aatgaatgaattggcagcaaaagttgaatgtacagaCTAGCC ATtatttgaaaaCGTGGTACAGTATACTCATAtaaccgatgatgaggagctgtaaaaa t" /listShort="comFB, comFC, yvyF, S1353, flgM, yvyG, flgK, flgL, yviE, fliW, csrA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3507744) /Source="Nicolas_upshifts" /id="U2776" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.797202797202797" /psig=1 /xcortree=2253 /SigmaFactorBS="aatgaatgaattggcagcaaaagttgaatgtacagaCTAGCC ATtatttgaaaaCGTGGTACAGTATACTCATAtaaccgatgatgaggagctgtaaaaa t" /listShort="comFB, comFC, yvyF, S1353, flgM, yvyG, flgK, flgL, yviE, fliW, csrA" /GFF_Attribute="listLong" promotor_-35 complement(3507761..3507768) /Source="Nicolas_upshift_promotors" /id="U2776" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.797202797202797" /psig=1 /xcortree=2253 /SigmaFactorBS="aatgaatgaattggcagcaaaagttgaatgtacagaCTAGCC ATtatttgaaaaCGTGGTACAGTATACTCATAtaaccgatgatgaggagctgtaaaaa t" /listShort="comFB, comFC, yvyF, S1353, flgM, yvyG, flgK, flgL, yviE, fliW, csrA" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3507765..3509156) /gene="comFA" /locus_tag="BSU_35470" /old_locus_tag="BSU35470" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:8045895, 11359569, 12123453, 16009133, 21397556, 28559293" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8045895, 11359569, 12123453, 16009133, 21397556, 28559293; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="ATP-dependent helicase competence protein" /protein_id="NP_391427.1" /db_xref="EnsemblGenomes-Gn:BSU35470" /db_xref="EnsemblGenomes-Tr:CAB15564" /db_xref="GOA:P39145" /db_xref="InterPro:IPR001650" /db_xref="InterPro:IPR006935" /db_xref="InterPro:IPR014001" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG10395" /db_xref="UniProtKB/Swiss-Prot:P39145" /translation="MNVPVEKNSSFSKELQQTLRSRHLLRTELSFSDEMIEWHIKNGY ITAENSISINKRRYRCNRCGQTDQRYFSFYHSSGKNKLYCRSCVMMGRVSEEVPLYSW KEENESNWKSIKLTWDGKLSSGQQKAANVLIEAISKKEELLIWAVCGAGKTEMLFPGI ESALNQGLRVCIATPRTDVVLELAPRLKAAFQGADISALYGGSDDKGRLSPLMISTTH QLLRYKDAIDVMIIDEVDAFPYSADQTLQFAVQKARKKNSTLVYLSATPPKELKRKAL NGQLHSVRIPARHHRKPLPEPRFVWCGNWKKKLNRNKIPPAVKRWIEFHVKEGRPVFL FVPSVSILEKAAACFKGVHCRTASVHAEDKHRKEKVQQFRDGQLDLLITTTILERGVT VPKVQTGVLGAESSIFTESALVQIAGRTGRHKEYADGDVIYFHFGKTKSMLDARKHIK EMNELAAKVECTD*" gene complement(3507765..3509156) /gene="comFA" /locus_tag="BSU_35470" /old_locus_tag="BSU35470" promotor_-10 complement(3509170..3509189) /Source="Nicolas_upshift_promotors" /id="U2777" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.992007992007992" /psig="0.997002997002997" /xcortree=2970 /SigmaFactorBS="ttagagcggagatttttttatattcttattttaatAGTTGGA CagaaaatattcatTCAGGCATACTGTTTCGAAAggaggcgtgctatgtgaatgtgcc a" /listShort="comFA, comFB, comFC, yvyF, S1353, flgM, yvyG, flgK, flgL, yviE, fliW, csrA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3509185) /Source="Nicolas_upshifts" /id="U2777" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.992007992007992" /psig="0.997002997002997" /xcortree=2970 /SigmaFactorBS="ttagagcggagatttttttatattcttattttaatAGTTGGA CagaaaatattcatTCAGGCATACTGTTTCGAAAggaggcgtgctatgtgaatgtgcc a" /listShort="comFA, comFB, comFC, yvyF, S1353, flgM, yvyG, flgK, flgL, yviE, fliW, csrA" /GFF_Attribute="listLong" promotor_-35 complement(3509203..3509210) /Source="Nicolas_upshift_promotors" /id="U2777" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.992007992007992" /psig="0.997002997002997" /xcortree=2970 /SigmaFactorBS="ttagagcggagatttttttatattcttattttaatAGTTGGA CagaaaatattcatTCAGGCATACTGTTTCGAAAggaggcgtgctatgtgaatgtgcc a" /listShort="comFA, comFB, comFC, yvyF, S1353, flgM, yvyG, flgK, flgL, yviE, fliW, csrA" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3509262..3510107) /gene="fakBA" /locus_tag="BSU_35480" /old_locus_tag="BSU35480" /EC_number="2.7.2.-" /function="16.11: Scavenge (Catabolism)" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:3926750, 17114254, 19390149, 22720735, 25002480, 26774272, 27435445" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 3926750, 17114254, 19390149, 22720735, 25002480, 26774272, 27435445; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="fatty acid kinase fatty acid binding subunit A" /protein_id="NP_391428.1" /db_xref="EnsemblGenomes-Gn:BSU35480" /db_xref="EnsemblGenomes-Tr:CAB15565" /db_xref="GOA:P32436" /db_xref="InterPro:IPR003797" /db_xref="PDB:3FYS" /db_xref="SubtiList:BG10394" /db_xref="UniProtKB/Swiss-Prot:P32436" /translation="MNIAVVTDSTAYIPKEMREQHQIHMIPLQVVFREETYREEIELD WKSFYEEVKKHNELPTTSQPPIGELVALYEELGKSYDAVISIHLSSGISGTFSSAAAA DSMVDNIDVYPFDSEISCLAQGFYALKAAELIKNGASSPEDIIKELEEMKKTVRAYFM VDDLAHLQRGGRLSSAQAFIGSLLKVKPILHFDNKVIVPFEKIRTRKKAISRIYELLD EDASKGLPMRAAVIHANREEEAAKIIEELSAKYPHVEFYNSYFGAVIGTHLGEGALGI CWCFK*" gene complement(3509262..3510107) /gene="fakBA" /locus_tag="BSU_35480" /old_locus_tag="BSU35480" downshifts complement(3509273) /Source="Nicolas_upshifts" /id="D1835" /incds=0 /nref=207 /ntot=249 /MaxReadThrough="2.43976" /MaxDrop="5.65998" /score="25.7738948" /energy="-9.9" /TU="NA" /idTUdmin="U2779" /TUdmin=0 /isTUend="TRUE" promotor_-35 3509524..3509531 /Source="Nicolas_upshift_promotors" /id="U2778" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.897102897102897" /psig="0.978021978021978" /xcortree=2971 /SigmaFactorBS="tgcgaatcttctcaaaaggcacaattaccTTATTGTCaaaat gaaggataGGCTTTACCTTTAGAAGACTaccaatgaaggcttgggcgctgcttaatcg c" /listShort="S1354" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3509545..3509564 /Source="Nicolas_upshift_promotors" /id="U2778" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.897102897102897" /psig="0.978021978021978" /xcortree=2971 /SigmaFactorBS="tgcgaatcttctcaaaaggcacaattaccTTATTGTCaaaat gaaggataGGCTTTACCTTTAGAAGACTaccaatgaaggcttgggcgctgcttaatcg c" /listShort="S1354" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 3509555..3511287 /Source="Nicolas_S_feature" /locus_tag="new_3643957_3645689" /HighExp="C30, S2, C90, Pyr, T0.30H, GM 150, G/S, T-4.40H, T-3.40H, T1.30H" /AntisenseName="degU" /AntisenseCor="1.0564647169900101E-2" /AntisenseRegPval="-0.1" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.978" /TUlongSig="NA" /TUlongPSig="NA" /label="S1354" upshifts 3509555 /Source="Nicolas_upshifts" /id="U2778" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.897102897102897" /psig="0.978021978021978" /xcortree=2971 /SigmaFactorBS="tgcgaatcttctcaaaaggcacaattaccTTATTGTCaaaat gaaggataGGCTTTACCTTTAGAAGACTaccaatgaaggcttgggcgctgcttaatcg c" /listShort="S1354" /GFF_Attribute="listLong" promotor_-10 complement(3510134..3510153) /Source="Nicolas_upshift_promotors" /id="U2779" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.767232767232767" /psig="0.998001998001998" /xcortree=2329 /SigmaFactorBS="atgagatagtataataggagacttgccttttactaggcaggt CTTTttttaggctgccgtTTCCCTTACAATAGAGTTATaaagcaataaggcaggtatc g" /listShort="yviA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3510153) /Source="Nicolas_upshifts" /id="U2779" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.767232767232767" /psig="0.998001998001998" /xcortree=2329 /SigmaFactorBS="atgagatagtataataggagacttgccttttactaggcaggt CTTTttttaggctgccgtTTCCCTTACAATAGAGTTATaaagcaataaggcaggtatc g" /listShort="yviA" /GFF_Attribute="listLong" promotor_-35 complement(3510168..3510171) /Source="Nicolas_upshift_promotors" /id="U2779" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.767232767232767" /psig="0.998001998001998" /xcortree=2329 /SigmaFactorBS="atgagatagtataataggagacttgccttttactaggcaggt CTTTttttaggctgccgtTTCCCTTACAATAGAGTTATaaagcaataaggcaggtatc g" /listShort="yviA" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3510205..3510894) /gene="degU" /locus_tag="BSU_35490" /old_locus_tag="BSU35490" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:10908654, 11557812, 12471443, 12950930, 14563871, 15342569, 15598897, 17590234, 17827323, 21736639, 22677979, 24847778, 25288929, 25880922, 25887289, 27920766" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10908654, 11557812, 12471443, 12950930, 14563871, 15342569, 15598897, 17590234, 17827323, 21736639, 22677979, 24847778, 25288929, 25880922, 25887289, 27920766; Product type r : regulator" /codon_start=1 /transl_table=11 /product="two-component response regulator" /protein_id="NP_391429.1" /db_xref="EnsemblGenomes-Gn:BSU35490" /db_xref="EnsemblGenomes-Tr:CAB15566" /db_xref="GOA:P13800" /db_xref="InterPro:IPR000792" /db_xref="InterPro:IPR001789" /db_xref="InterPro:IPR011006" /db_xref="InterPro:IPR016032" /db_xref="InterPro:IPR036388" /db_xref="SubtiList:BG10393" /db_xref="UniProtKB/Swiss-Prot:P13800" /translation="MTKVNIVIIDDHQLFREGVKRILDFEPTFEVVAEGDDGDEAARI VEHYHPDVVIMDINMPNVNGVEATKQLVELYPESKVIILSIHDDENYVTHALKTGARG YLLKEMDADTLIEAVKVVAEGGSYLHPKVTHNLVNEFRRLATSGVSAHPQHEVYPEIR RPLHILTRRECEVLQMLADGKSNRGIGESLFISEKTVKNHVSNILQKMNVNDRTQAVV VAIKNGWVEMR*" gene complement(3510205..3510894) /gene="degU" /locus_tag="BSU_35490" /old_locus_tag="BSU35490" downshifts complement(3510219) /Source="Nicolas_upshifts" /id="D1836" /incds=0 /nref=178 /ntot=235 /MaxReadThrough="5.12878" /MaxDrop="6.38336" /score="20.9249268" /energy="-12.8" /TU="U2781" /idTUdmin="U2779" /TUdmin="-946" /isTUend="FALSE" S_feature complement(3510895..3510976) /Source="Nicolas_S_feature" /locus_tag="new_3645297_3645378_c" /HighExp="M40t90, Lbtran, M0t90, LBGtran, G180, T3.0H, M40t45, C90, T3.30H, T2.30H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.998" /TUlongSig="NA" /TUlongPSig="NA" /label="S1355" CDS complement(3510977..3512134) /gene="degS" /locus_tag="BSU_35500" /old_locus_tag="BSU35500" /EC_number="2.7.3.-" /function="16.3: Control" /function="16.12: Sense" /experiment="publication(s) with functional evidences, PMID:10908654, 11557812, 12471443, 12950930, 14563871, 15342569, 15598897, 17590234, 17827323, 21736639, 22677979, 24847778, 25288929, 25880922, 25887289, 27920766" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10908654, 11557812, 12471443, 12950930, 14563871, 15342569, 15598897, 17590234, 17827323, 21736639, 22677979, 24847778, 25288929, 25880922, 25887289, 27920766; Product type rc : receptor" /codon_start=1 /transl_table=11 /product="two-component sensor histidine kinase [DegU]" /protein_id="NP_391430.1" /db_xref="EnsemblGenomes-Gn:BSU35500" /db_xref="EnsemblGenomes-Tr:CAB15567" /db_xref="GOA:P13799" /db_xref="InterPro:IPR003594" /db_xref="InterPro:IPR005467" /db_xref="InterPro:IPR008595" /db_xref="InterPro:IPR011712" /db_xref="InterPro:IPR016381" /db_xref="InterPro:IPR036890" /db_xref="SubtiList:BG10392" /db_xref="UniProtKB/Swiss-Prot:P13799" /translation="MNKTKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLV EELKQIKQQVYEVIELGDKLEVQTRHARNRLSEVSRNFHRFSEEEIRNAYEKAHKLQV ELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLREVGLLL ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGAEDG FQEIKNLRQNVRNALYEVRRIIYDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQ CIGETEDQRLAPQFEVALFRLAQEAVSNALKHSESEEITVKVEITKDFVILMIKDNGK GFDLKEAKEKKNKSFGLLGMKERVDLLEGTMTIDSKIGLGTFIMIKVPLSL*" gene complement(3510977..3512134) /gene="degS" /locus_tag="BSU_35500" /old_locus_tag="BSU35500" S_feature complement(3512135..3512262) /Source="Nicolas_S_feature" /locus_tag="new_3646537_3646664_c" /HighExp="T0.30H, Lbtran, M9-stat, T3.0H, T1.0H, HiOs, T1.30H, T2.30H, T3.30H, LBGstat" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.998" /TUlongSig="NA" /TUlongPSig="NA" /label="S1356" promotor_-35 3512182..3512185 /Source="Nicolas_upshift_promotors" /id="U2780" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.656343656343656" /psig="0.999000999001" /xcortree=2533 /SigmaFactorBS="ggcgttgtcatatatttttattataaatgtaATTGatctgca aattatgTCGAATTATAATGAAAGAATgcgtatattctagaaaaaaacatttttatat a" /listShort="S1357, yvyE, yvhJ" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3512200..3512219 /Source="Nicolas_upshift_promotors" /id="U2780" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.656343656343656" /psig="0.999000999001" /xcortree=2533 /SigmaFactorBS="ggcgttgtcatatatttttattataaatgtaATTGatctgca aattatgTCGAATTATAATGAAAGAATgcgtatattctagaaaaaaacatttttatat a" /listShort="S1357, yvyE, yvhJ" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 3512211..3512297 /Source="Nicolas_S_feature" /locus_tag="new_3646613_3646699" /HighExp="UNK1, Cold, C30, Lbexp, MG 15, G135, G180, G150, Paraq, Oxctl" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S1357" upshifts 3512211 /Source="Nicolas_upshifts" /id="U2780" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.656343656343656" /psig="0.999000999001" /xcortree=2533 /SigmaFactorBS="ggcgttgtcatatatttttattataaatgtaATTGatctgca aattatgTCGAATTATAATGAAAGAATgcgtatattctagaaaaaaacatttttatat a" /listShort="S1357, yvyE, yvhJ" /GFF_Attribute="listLong" promotor_-10 complement(3512256..3512275) /Source="Nicolas_upshift_promotors" /id="U2781" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.928071928071928" /psig="0.998001998001998" /xcortree=2274 /SigmaFactorBS="agactgcctatacaaattcgtacagtcttTAGAATTTttgtg cgtatTTTGGTATCATAAAGAGTAGatagtatataaaaatgtttttttctagaatata c" /listShort="S1356, degS, S1355, degU, yviA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3512262) /Source="Nicolas_upshifts" /id="U2781" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.928071928071928" /psig="0.998001998001998" /xcortree=2274 /SigmaFactorBS="agactgcctatacaaattcgtacagtcttTAGAATTTttgtg cgtatTTTGGTATCATAAAGAGTAGatagtatataaaaatgtttttttctagaatata c" /listShort="S1356, degS, S1355, degU, yviA" /GFF_Attribute="listLong" promotor_-35 3512279..3512287 /Source="Nicolas_upshift_promotors" /id="U2782" /multdbtbs="-" /comp="M2" /sig="SigI" /pcomp="0.995004995004995" /psig="0.995004995004995" /xcortree=1725 /SigmaFactorBS="acatttttatatactatctactctttatgataccaaaataCG CACAAAAattctaaagactgTACGAATTTgtataggcagtcttttatgcttagcagga g" /listShort="yvyE, yvhJ" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 complement(3512286..3512293) /Source="Nicolas_upshift_promotors" /id="U2781" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.928071928071928" /psig="0.998001998001998" /xcortree=2274 /SigmaFactorBS="agactgcctatacaaattcgtacagtcttTAGAATTTttgtg cgtatTTTGGTATCATAAAGAGTAGatagtatataaaaatgtttttttctagaatata c" /listShort="S1356, degS, S1355, degU, yviA" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 3512299 /Source="Nicolas_upshifts" /id="U2782" /multdbtbs="-" /comp="M2" /sig="SigI" /pcomp="0.995004995004995" /psig="0.995004995004995" /xcortree=1725 /SigmaFactorBS="acatttttatatactatctactctttatgataccaaaataCG CACAAAAattctaaagactgTACGAATTTgtataggcagtcttttatgcttagcagga g" /listShort="yvyE, yvhJ" /GFF_Attribute="listLong" promotor_-10 3512301..3512309 /Source="Nicolas_upshift_promotors" /id="U2782" /multdbtbs="-" /comp="M2" /sig="SigI" /pcomp="0.995004995004995" /psig="0.995004995004995" /xcortree=1725 /SigmaFactorBS="acatttttatatactatctactctttatgataccaaaataCG CACAAAAattctaaagactgTACGAATTTgtataggcagtcttttatgcttagcagga g" /listShort="yvyE, yvhJ" /GFF_Attribute="listLong" /label="promotor_-10" CDS 3512351..3513004 /gene="yvyE" /locus_tag="BSU_35510" /old_locus_tag="BSU35510" /function="16.2: Construct biomass (Anabolism)" /function="16.13: Shape" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 11116084, 15103642, 21239490, 22404850; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative translation regulator" /protein_id="NP_391431.1" /db_xref="EnsemblGenomes-Gn:BSU35510" /db_xref="EnsemblGenomes-Tr:CAB15568" /db_xref="InterPro:IPR001498" /db_xref="InterPro:IPR015269" /db_xref="InterPro:IPR015796" /db_xref="InterPro:IPR020568" /db_xref="InterPro:IPR020569" /db_xref="InterPro:IPR023582" /db_xref="InterPro:IPR035647" /db_xref="InterPro:IPR036956" /db_xref="SubtiList:BG11052" /db_xref="UniProtKB/Swiss-Prot:P32437" /translation="MLHSYFTVKEAGEHEIVIEKSRFICHLSRVSTEQEAQEFIQKIK KQHWNATHNCSAYVIGENDHIQKANDDGEPSGTAGVPMLEVLKKRRLKDTCAVVTRYF GGIKLGAGGLIRAYGKSVSEGLNHIGVVERKLMRIMHTSADYTWLGKIENELRESQFL LKEIHYSENVEFETYVEEKETNAFSEWMTELTNGKSDIKEGELTYLEKAVNHIKETE* " gene 3512351..3513004 /gene="yvyE" /locus_tag="BSU_35510" /old_locus_tag="BSU35510" S_feature complement(3512707..3513299) /Source="Nicolas_S_feature" /locus_tag="new_3647109_3647701_c" /HighExp="Etha, M9-stat, Gly, C30, B60, Salt, T0.30H, Sw, LoTm, S8" /AntisenseName="yvyE" /AntisenseCor="-0.139956338862644" /AntisenseRegPval="-1.7" /CDS_PredictionProba="NA" /TUshortSig="SigB" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1358" CDS 3513004..3514179 /gene="tagV" /locus_tag="BSU_35520" /old_locus_tag="BSU35520" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:19099556, 29107701" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 19099556, 29107701; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="teichoic acid-peptidoglycan tethering enzyme (LCP component) with transcription regulator domain" /protein_id="NP_391432.1" /db_xref="EnsemblGenomes-Gn:BSU35520" /db_xref="EnsemblGenomes-Tr:CAB15569" /db_xref="GOA:P96499" /db_xref="InterPro:IPR004474" /db_xref="PDB:3NXH" /db_xref="SubtiList:BG12449" /db_xref="UniProtKB/Swiss-Prot:P96499" /translation="MAERVRVRVRKKKKSKRRKILKRIMLLFALALLVVVGLGGYKLY KTINAADESYDALSRGNKSNLRNEVVDMKKKPFSILFMGIEDYATKGQKGRSDSLIVV TLDPKNKTMKMLSIPRDTRVQLAGDTTGSKTKINAAYSKGGKDETVETVENFLQIPID KYVTVDFDGFKDVINEVGGIDVDVPFDFDEKSDVDESKRIYFKKGEMHLNGEEALAYA RMRKQDKRGDFGRNDRQKQILNALIDRMSSASNIAKIDKIAEKASENVETNIRITEGL ALQQIYSGFTSKKIDTLSITGSDLYLGPNNTYYFEPDATNLEKVRKTLQEHLDYTPDT STGTSGTEDGTDSSSSSGSTGSTGTTTDGTTNGSSYSNDSSTSSNNSTTNSTTDSSY* " gene 3513004..3514179 /gene="tagV" /locus_tag="BSU_35520" /old_locus_tag="BSU35520" promotor_-10 complement(3513295..3513313) /Source="Nicolas_upshift_promotors" /id="U2783" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=201 /SigmaFactorBS="gtgtgtcacgcggaatgctcagcattttcatGGTTTTAtttt tgggatccaGGGTAACAACAATAAGAGAgtctgatctccctttttgtcctttagtcgc g" /listShort="S1358" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3513304) /Source="Nicolas_upshifts" /id="U2783" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=201 /SigmaFactorBS="gtgtgtcacgcggaatgctcagcattttcatGGTTTTAtttt tgggatccaGGGTAACAACAATAAGAGAgtctgatctccctttttgtcctttagtcgc g" /listShort="S1358" /GFF_Attribute="listLong" promotor_-35 complement(3513327..3513333) /Source="Nicolas_upshift_promotors" /id="U2783" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=201 /SigmaFactorBS="gtgtgtcacgcggaatgctcagcattttcatGGTTTTAtttt tgggatccaGGGTAACAACAATAAGAGAgtctgatctccctttttgtcctttagtcgc g" /listShort="S1358" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 3514151 /Source="Nicolas_upshifts" /id="D1837" /incds=0 /nref=199 /ntot=276 /MaxReadThrough="2.38202" /MaxDrop="7.1642" /score="16.6000843" /energy="-18.6" /TU="NA" /idTUdmin="U2782" /TUdmin=4 /isTUend="TRUE" CDS complement(3514252..3515328) /gene="tagO" /locus_tag="BSU_35530" /old_locus_tag="BSU35530" /EC_number="2.7.8.33" /function="16.8: Protect" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:12101296, 12682299, 15849754, 16850406, 17012386, 18156271, 27312048" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12101296, 12682299, 15849754, 16850406, 17012386, 18156271, 27312048; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="UDP-N-acetylglucosamine:undecaprenyl-P N-acetylglucosaminyl-1-P transferase" /protein_id="NP_391433.1" /db_xref="EnsemblGenomes-Gn:BSU35530" /db_xref="EnsemblGenomes-Tr:CAB15570" /db_xref="GOA:O34753" /db_xref="InterPro:IPR000715" /db_xref="InterPro:IPR018480" /db_xref="SubtiList:BG12684" /db_xref="UniProtKB/Swiss-Prot:O34753" /translation="MLDERMIRIVVAFIVSLLTVLIITPIVKRIAIKIGAVDQPSNRK VHDKIMPRMGGLAIFIGVVAGVLASGIYTETRMTAITVGAFIIIVLGILDDKYQLSAK VKFLIQLGVAIMIVSTGLKMDFFSVPFLTERFELGWMAYPLTVLWIVGITNAINLIDG LDGLAAGLSVIGLSTIAVMALSGGKVLILSLSLVVIASTLGFLFYNFHPAKIFMGDTG SLFLGYSISILSLLGLYKSVTLFSIVIPIIILGVPIFDTTFAIIRRILNKQPISAPDK SHIHHRLMAFGLSHRMSVLVIYLIGFIFSISAIVLKSATIWLSLFIIFILIIFMQIIA EVTGLVNEKFKPFTKFYKRLVKRN*" gene complement(3514252..3515328) /gene="tagO" /locus_tag="BSU_35530" /old_locus_tag="BSU35530" downshifts complement(3514268) /Source="Nicolas_upshifts" /id="D1838" /incds=0 /nref=221 /ntot=280 /MaxReadThrough="1.7614" /MaxDrop="8.41647" /score="29.109706" /energy="-11.6" /TU="NA" /idTUdmin="U2785" /TUdmin="-1" /isTUend="TRUE" promotor_-35 3514314..3514323 /Source="Nicolas_upshift_promotors" /id="U2784" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.993006993006993" /psig="0.993006993006993" /xcortree=1388 /SigmaFactorBS="tgtaaacggcttaaatttttcattcacgaGTCCTGTCACttc tgctatgattTGCATAAAAATAATCAAAATgaagataataaacaaagaaagccaaatt g" /listShort="S1359" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3514337..3514356 /Source="Nicolas_upshift_promotors" /id="U2784" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.993006993006993" /psig="0.993006993006993" /xcortree=1388 /SigmaFactorBS="tgtaaacggcttaaatttttcattcacgaGTCCTGTCACttc tgctatgattTGCATAAAAATAATCAAAATgaagataataaacaaagaaagccaaatt g" /listShort="S1359" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 3514345..3515578 /Source="Nicolas_S_feature" /locus_tag="new_3648747_3649980" /HighExp="S8, S6, S7, S5, BT, S4, B36, Pyr, S3, G/S" /AntisenseName="tagO" /AntisenseCor="-0.60515751332040901" /AntisenseRegPval="-27.5" /CDS_PredictionProba="NA" /TUshortSig="SigK" /TUshortPSig="0.993" /TUlongSig="NA" /TUlongPSig="NA" /label="S1359" upshifts 3514345 /Source="Nicolas_upshifts" /id="U2784" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.993006993006993" /psig="0.993006993006993" /xcortree=1388 /SigmaFactorBS="tgtaaacggcttaaatttttcattcacgaGTCCTGTCACttc tgctatgattTGCATAAAAATAATCAAAATgaagataataaacaaagaaagccaaatt g" /listShort="S1359" /GFF_Attribute="listLong" S_feature complement(3515329..3515411) /Source="Nicolas_S_feature" /locus_tag="new_3649731_3649813_c" /HighExp="LPhT, Cold, LoTm, T0.30H, T3.0H, LBGstat, T1.30H, T1.0H, T2.30H, LBGexp" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.67123699999999997" /TUshortSig="SigA, Sig-" /TUshortPSig="1, 0.018" /TUlongSig="NA" /TUlongPSig="NA" /label="S1360" promotor_-10 complement(3515399..3515418) /Source="Nicolas_upshift_promotors" /id="U2785" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.856143856143856" /psig=1 /xcortree=2139 /SigmaFactorBS="cctataaattgggatgcgcgttttttgattatacgTGTTTCT ttttgatgaagCTTGTTATAATAACTAAGGAgaaggtataatggaaggaacggttctc t" /listShort="S1360, tagO" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3515411) /Source="Nicolas_upshifts" /id="U2785" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.856143856143856" /psig=1 /xcortree=2139 /SigmaFactorBS="cctataaattgggatgcgcgttttttgattatacgTGTTTCT ttttgatgaagCTTGTTATAATAACTAAGGAgaaggtataatggaaggaacggttctc t" /listShort="S1360, tagO" /GFF_Attribute="listLong" promotor_-35 complement(3515430..3515436) /Source="Nicolas_upshift_promotors" /id="U2785" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.856143856143856" /psig=1 /xcortree=2139 /SigmaFactorBS="cctataaattgggatgcgcgttttttgattatacgTGTTTCT ttttgatgaagCTTGTTATAATAACTAAGGAgaaggtataatggaaggaacggttctc t" /listShort="S1360, tagO" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3515473..3516666) /gene="tuaH" /locus_tag="BSU_35540" /old_locus_tag="BSU35540" /EC_number="2.4.1.-" /function="16.13: Shape" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 4975313, 10048024, 11994144, 26284661; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative glycosyltransferase (teichuronic acid)" /protein_id="NP_391434.1" /db_xref="EnsemblGenomes-Gn:BSU35540" /db_xref="EnsemblGenomes-Tr:CAB15571" /db_xref="GOA:O32267" /db_xref="SubtiList:BG12695" /db_xref="UniProtKB/Swiss-Prot:O32267" /translation="METKEAIIHVIVATAEWGKDQLRYRRHRLAEFLAAQEETKEVIW VCPAPRAQGKEFQEVHSGIRQFAVKDLLQKKMFRFGRYTDVFYRHKLSPLLDELTPAS ANGERCCLWYTFPGFPLLSSLYSWDQVIYDCSDLWAAPISGRSNLLSEFRRKVIKSAE LRIIQRADSITCSSDYLHKEVDKKLTAGREKVHTVENGVEYELFSANKQAPDRSILQG REGIVLGFIGGIKPKLDFKMIKEAALQKPDWTFLWVGPDATNGDVSFQELLRLPNVIW TGPADPKEVPHYMELIDIGIMPYKQSPYNQAVFPLKLFEFLAAGKPVVGTNLPSTSKM QKPYVYEYVEGDHPIDFIAACEKVLGQNGDETYKEMRRNIARTQDWNCLFRQIMKYTG IQKHA*" gene complement(3515473..3516666) /gene="tuaH" /locus_tag="BSU_35540" /old_locus_tag="BSU35540" downshifts complement(3515503) /Source="Nicolas_upshifts" /id="D1839" /incds=0 /nref=23 /ntot=141 /MaxReadThrough="7.20583" /MaxDrop="4.88676" /score="4.72365619" /energy="-10.8" /TU="U2786" /idTUdmin="U2785" /TUdmin="-1236" /isTUend="FALSE" CDS complement(3516695..3517453) /gene="tuaG" /locus_tag="BSU_35550" /old_locus_tag="BSU35550" /EC_number="2.4.1.-" /function="16.13: Shape" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 4975313, 10048024, 11994144, 26284661; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative glycosyltransferase (teichuronic acid)" /protein_id="NP_391435.1" /db_xref="EnsemblGenomes-Gn:BSU35550" /db_xref="EnsemblGenomes-Tr:CAB15572" /db_xref="GOA:O32268" /db_xref="InterPro:IPR001173" /db_xref="InterPro:IPR029044" /db_xref="SubtiList:BG12694" /db_xref="UniProtKB/Swiss-Prot:O32268" /translation="MTNWKPLVSVITPSYNARDYIEDTVHSVLDQSHPHWEMIIVDDC STDGTRDILQQYEKIDERIHVVYLEENSGAAVARNKALERAQGRYVAFLDSDDKWKKD KLEKQLEFMMERSCAFSFTGYSLMAQDGTPLDKFIHAPESLTYDDALKNTIIGCLTVM IDREQTGQIQMPNIRTRQDLATWLSLLKKGFTAYGMNECLAEYRLVNNSISSNKWKAA KKTWFVYREIERLHFMKATWCFVQYAKNAVKKRL*" gene complement(3516695..3517453) /gene="tuaG" /locus_tag="BSU_35550" /old_locus_tag="BSU35550" CDS complement(3517477..3518157) /gene="tuaF" /locus_tag="BSU_35560" /old_locus_tag="BSU35560" /function="16.13: Shape" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 4975313, 10048024, 11994144, 26284661; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative hydrolase involved in teichuronic acid synthesis" /protein_id="NP_391436.1" /db_xref="EnsemblGenomes-Gn:BSU35560" /db_xref="EnsemblGenomes-Tr:CAB15573" /db_xref="GOA:O32269" /db_xref="InterPro:IPR003856" /db_xref="SubtiList:BG12693" /db_xref="UniProtKB/Swiss-Prot:O32269" /translation="MNDILIRIARRIKKNIIWIIAVPIILGAAGYILPSQIADQKSYT AEDTLAVGSYDHPVYNSTEEIPLLLKSDSFLKEALPDEKDEDVAEIKEKLTINTESKS LLTLSYSDEDKDRTESVLNAISSTFLKNDQKLYAEREAVIRSSIDALEGESVSEDSKV DKERFLYELKNTQLNLKAASVTDSETVSETAGGGMSPKKKAVLGVMIGLTIAFMFVVI PEFFRESF*" gene complement(3517477..3518157) /gene="tuaF" /locus_tag="BSU_35560" /old_locus_tag="BSU35560" CDS complement(3518186..3519652) /gene="tuaE" /locus_tag="BSU_35570" /old_locus_tag="BSU35570" /function="16.13: Shape" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 4975313, 10048024, 11994144, 15849754, 16850406, 26284661; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="putative polymerase of teichuronic acid repeating units" /protein_id="NP_391437.1" /db_xref="EnsemblGenomes-Gn:BSU35570" /db_xref="EnsemblGenomes-Tr:CAB15574" /db_xref="GOA:O32270" /db_xref="InterPro:IPR007016" /db_xref="SubtiList:BG12692" /db_xref="UniProtKB/Swiss-Prot:O32270" /translation="MSIKRSAVHTLALLAAAIFGVVLLLGAIHKDIGFMQMAAVLAVL AIGLFLLTLATAFTTKERLFMAVIYILIACTFLNNAFFAIHLGFFSLFLYRLLLIAAG CLHIFGMVRNRTHIERWHGLQVKGILLFFAFWFIYGLVSLLWAKSVTVGLKYLALLAM GIFFIYLIVMYVQKMERLMIVYAIWLVMTVFLMIIGFYNHITHHHLASSTLYSGPEYK QHYPTSVFFNQNDFATFLSISFFFYITMMKNIKNGYIKAIGLVLSLCALYLIFATGSR ASLLGIFAGIAVYIFIVLPPVLKRMAIWLSAAGIALFAVLFASKIYSKFWELFLAPQT LHSFHDRLPSNVARANLLKNAWHFFLDSYGFGVGAGNVSYYLEHYAVYDTDNVAEVHN WLVEILANFGLFIMLGYLSVYAYLIWVLYKFYERKLENQSKLITEGLITAMVSFLVSS ISPSSVSNLFFHWVFMALVIAAVNVLRRSRQMPEPMYR*" gene complement(3518186..3519652) /gene="tuaE" /locus_tag="BSU_35570" /old_locus_tag="BSU35570" S_feature complement(3519653..3519736) /Source="Nicolas_S_feature" /locus_tag="new_3654055_3654138_c" /HighExp="LPhT, S3, B60, S7, S4, S6, LBGstat, BI, S8, S5" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="Sig-" /TUshortPSig="0.018" /TUlongSig="NA" /TUlongPSig="NA" /label="S1361" CDS complement(3519737..3521122) /gene="tuaD" /locus_tag="BSU_35580" /old_locus_tag="BSU35580" /EC_number="1.1.1.22" /function="16.2: Construct biomass (Anabolism)" /function="16.8: Protect" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:10376820, 10913081, 12970183, 16000785, 26284661" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10376820, 10913081, 12970183, 16000785, 26284661; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="UDP-glucose 6-dehydrogenase (teichuronic acid)" /protein_id="NP_391438.1" /db_xref="EnsemblGenomes-Gn:BSU35580" /db_xref="EnsemblGenomes-Tr:CAB15575" /db_xref="GOA:O32271" /db_xref="InterPro:IPR001732" /db_xref="InterPro:IPR008927" /db_xref="InterPro:IPR014026" /db_xref="InterPro:IPR014027" /db_xref="InterPro:IPR017476" /db_xref="InterPro:IPR021157" /db_xref="InterPro:IPR028357" /db_xref="InterPro:IPR036220" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG12691" /db_xref="UniProtKB/Swiss-Prot:O32271" /translation="MKKIAVIGTGYVGLVSGTCFAEIGNKVVCCDIDESKIRSLKNGV IPIYEPGLADLVEKNVLDQRLTFTNDIPSAIRASDIIYIAVGTPMSKTGEADLTYVKA AAKTIGEHLNGYKVIVNKSTVPVGTGKLVQSIVQKASKGRYSFDVVSNPEFLREGSAI HDTMNMERAVIGSTSHKAAAIIEELHQPFHAPVIKTNLESAEMIKYAANAFLATKISF INDIANICERVGADVSKVADGVGLDSRIGRKFLKAGIGFGGSCFPKDTTALLQIAKSA GYPFKLIEAVIETNEKQRVHIVDKLLTVMGSVKGRTISVLGLAFKPNTNDVRSAPALD IIPMLQQLGAHVKAYDPIAIPEASAILGEQVEYYTDVYAAMEDTDACLILTDWPEVKE MELVKVKTLLKQPVIIDGRNLFSLEEMQAAGYIYHSIGRPAVRGTEPSDKYFPGLPLE ELAKDLGSVNL*" gene complement(3519737..3521122) /gene="tuaD" /locus_tag="BSU_35580" /old_locus_tag="BSU35580" CDS complement(3521184..3522353) /gene="tuaC" /locus_tag="BSU_35590" /old_locus_tag="BSU35590" /EC_number="2.4.1.-" /function="16.13: Shape" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 4975313, 10048024, 11994144, 26284661; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative glycosyltransferase (teichuronic acid)" /protein_id="NP_391439.1" /db_xref="EnsemblGenomes-Gn:BSU35590" /db_xref="EnsemblGenomes-Tr:CAB15576" /db_xref="GOA:O32272" /db_xref="InterPro:IPR001296" /db_xref="InterPro:IPR028098" /db_xref="SubtiList:BG12690" /db_xref="UniProtKB/Swiss-Prot:O32272" /translation="MKILWITSVYPSSMKPGEGVFHETQVQELQKLGLDITVICPRPF HSAPVRMLKKTYRKKDVRPEYEIRKGIPVYRPFYRAVPGQLKWAQPHRRIASAVLKTM KQRDLYPDLIHAHFAMPSGGAAAVVSESAQIPYVLTLHGSDVNVYPHYSKGAFKAFKR AVGSASVVLAVSHKLQEEAKKLSGFDSSVLPIGIQLSRFQGNEETKEEIRKRLGLPLD QRLAVYVGRLVREKGIFELSEAIESLQDSPKAVFVGDGPAKSTLTQKGHIVTGQVPNH QVRDYLLAADLFVLPSYSEGMPTVVIEALALRVPVICTDVGGVSSLFGKHQHLLIKPK SAQALAEAITRYEHEQIWKPEVADDLYETVQAQFDAGKNAKALHHQYQTVTKTSV*" gene complement(3521184..3522353) /gene="tuaC" /locus_tag="BSU_35590" /old_locus_tag="BSU35590" CDS complement(3522350..3523801) /gene="tuaB" /locus_tag="BSU_35600" /old_locus_tag="BSU35600" /function="16.8: Protect" /function="16.13: Shape" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 10048024, 11994144, 15849754, 16850406, 22720735, 26284661; Product type t : transporter" /codon_start=1 /transl_table=11 /product="putative exporter involved in biosynthesis of teichuronic acid" /protein_id="NP_391440.1" /db_xref="EnsemblGenomes-Gn:BSU35600" /db_xref="EnsemblGenomes-Tr:CAB15577" /db_xref="GOA:O32273" /db_xref="InterPro:IPR002797" /db_xref="InterPro:IPR029303" /db_xref="SubtiList:BG12689" /db_xref="UniProtKB/Swiss-Prot:O32273" /translation="MPSITKQIMSGAKWTSISTMCITIIQIVQFALLGNMMTLTEFGL VGMITTVTVFAQIVLDMGFGAALIQRDDATERQLSTLYWLNIMTGVLLFVLLYVSSPV IAGFYQREELVFLVRILAIMFLIAPIGQQYQYMLQKQLHFNTLSKIEIFSNVLSFGYL AIAVFMMDAILAYVISQVLLQSSKGILYWAVYRKKWHPAFVFDLRGMKDFFSFGAFQL SSRLVNRLGANIDMILIGRFIGAEALGIYNLAYQIVTIPVLKINPIVTRVAFPIFAKN KYENSVIREGFLNMTKMLALVSFPLLIGLVSVSDAFITAVFGEKWLAAVPILNVLAIV GILRVLMNPNGSVLLAKGRADLAFYWDSGVLLLYGLSLFAAVQTGSLLTVAWVYAIIS VVNFLIGRWLLAYVIKLNLSAYFQSIMKPFLITAAMGIIAFGVSLSTEHFSMQAEMRL AISVAAGALCYLFLLVKAYPQTKSKLLRKGRLS*" gene complement(3522350..3523801) /gene="tuaB" /locus_tag="BSU_35600" /old_locus_tag="BSU35600" CDS complement(3523857..3524006) /gene="tuaAc" /locus_tag="BSU_35609" /old_locus_tag="BSU35609" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function; PubMedId: 7704262, 26284661; Product type e: enzyme" /pseudo /codon_start=1 /transl_table=11 /product="putative undecaprenyl-phosphate N-acetylgalactosaminyl-1-phosphate transferase; C-terminal part of TuaA" /db_xref="SubtiList:BG12688" /translation="WAQVNGGYDMTPKEKLIFDLYYIRNLTFTLELKIMLKTCKVVWT GDGAR*" gene complement(3523857..3524006) /gene="tuaAc" /locus_tag="BSU_35609" /old_locus_tag="BSU35609" /pseudo CDS complement(3523951..3524490) /gene="tuaAn" /locus_tag="BSU_35610" /old_locus_tag="BSU35610" /EC_number="2.7.8.-" /function="16.13: Shape" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function; PubMedId : 10048024, 11994144, 26284661; Product type e: enzyme" /pseudo /codon_start=1 /transl_table=11 /product="putative undecaprenyl-phosphate N-acetylgalactosaminyl-1-phosphate transferase; N-terminal part of TuaA" /translation="MSAEKSMNVSREFSVQQIHSFTLSEKTARYLAIKRVMDIWFALI GLAIALPMIAVFSILICLETPGPAIYTQERVGKGGKPFKLYKLRSMKIDAEKSGAVWA QKQDPRVTRIGAFIRRTRIDELPQLFNVLKGDMSMIGPRPERPVFTEKFQNEIPGFTQ RLGSGERRLRYDAEGKADI*" gene complement(3523951..3524490) /gene="tuaAn" /locus_tag="BSU_35610" /old_locus_tag="BSU35610" /pseudo misc_feature complement(3524546..3524563) /Source="Nicolas_upshift_promotors" /id="U2786" /multdbtbs="SigA" /comp="M6" /sig="Sig-" /pcomp="0.977022977022977" /psig="0.017982017982018" /xcortree=12 /SigmaFactorBS="cagaaaaaacacgtaattcacacttcttaacataccatttac atccaATTAACATCCGTCTGCTAaactgactggcataggtcatcataacatcccaaac a" /listShort="tuaA, tuaA, tuaB, tuaC, tuaD, S1361, tuaE, tuaF, tuaG, tuaH, S1360, tagO" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(3524550) /Source="Nicolas_upshifts" /id="U2786" /multdbtbs="SigA" /comp="M6" /sig="Sig-" /pcomp="0.977022977022977" /psig="0.017982017982018" /xcortree=12 /SigmaFactorBS="cagaaaaaacacgtaattcacacttcttaacataccatttac atccaATTAACATCCGTCTGCTAaactgactggcataggtcatcataacatcccaaac a" /listShort="tuaA, tuaA, tuaB, tuaC, tuaD, S1361, tuaE, tuaF, tuaG, tuaH, S1360, tagO" /GFF_Attribute="listLong" CDS complement(3524717..3526207) /gene="lytC" /locus_tag="BSU_35620" /old_locus_tag="BSU35620" /EC_number="3.5.1.28" /function="16.11: Scavenge (Catabolism)" /function="16.6: Maintain" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:1357079, 9537764, 14594841, 17298895, 19542270, 22469514" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1357079, 9537764, 14594841, 17298895, 19542270, 22469514; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="N-acetylmuramoyl-L-alanine amidase (major autolysin)" /protein_id="NP_391442.1" /db_xref="EnsemblGenomes-Gn:BSU35620" /db_xref="EnsemblGenomes-Tr:CAB15579" /db_xref="GOA:Q02114" /db_xref="InterPro:IPR002508" /db_xref="InterPro:IPR007253" /db_xref="SubtiList:BG10407" /db_xref="UniProtKB/Swiss-Prot:Q02114" /translation="MRSYIKVLTMCFLGLILFVPTALADNSVKRVGGSNRYGTAVQIS KQMYSTASTAVIVGGSSYADAISAAPLAYQKNAPLLYTNSDKLSYETKTRLKEMQTKN VIIVGGTPAVSSNTANQIKSLGISIKRIAGSNRYDTAARVAKAMGATSKAVILNGFLY ADAPAVIPYAAKNGYPILFTNKTSINSATTSVIKDKGISSTVVVGGTGSISNTVYNKL PSPTRISGSNRYELAANIVQKLNLSTSTVYVSNGFSYPDSIAGATLAAKKKQSLILTN GENLSTGARKIIGSKNMSNFMIIGNTPAVSTKVANQLKNPVVGETIFIDPGHGDQDSG AIGNGLLEKEVNLDIAKRVNTKLNASGALPVLSRSNDTFYSLQERVNKAASAQADLFL SIHANANDSSSPNGSETYYDTTYQAANSKRLAEQIQPKLAANLGTRDRGVKTAAFYVI KYSKMPSVLVETAFITNASDASKLKQAVYKDKAAQAIHDGTVSYYR*" gene complement(3524717..3526207) /gene="lytC" /locus_tag="BSU_35620" /old_locus_tag="BSU35620" downshifts complement(3524739) /Source="Nicolas_upshifts" /id="D1840" /incds=0 /nref=145 /ntot=213 /MaxReadThrough="3.26689" /MaxDrop="6.50948" /score="13.9455176" /energy="-13.3" /TU="NA" /idTUdmin="U2788" /TUdmin=0 /isTUend="TRUE" CDS complement(3526246..3528363) /gene="lytB" /locus_tag="BSU_35630" /old_locus_tag="BSU35630" /function="16.6: Maintain" /function="16.11: Scavenge (Catabolism)" /function="16.13: Shape" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:1357079, 16306698, 17269748" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1357079, 16306698, 17269748; Product type r: regulator" /codon_start=1 /transl_table=11 /product="modifier of major autolysin amidase LytC" /protein_id="NP_391443.1" /db_xref="EnsemblGenomes-Gn:BSU35630" /db_xref="EnsemblGenomes-Tr:CAB15580" /db_xref="GOA:Q02113" /db_xref="InterPro:IPR007253" /db_xref="InterPro:IPR013486" /db_xref="InterPro:IPR013693" /db_xref="SubtiList:BG10406" /db_xref="UniProtKB/Swiss-Prot:Q02113" /translation="MKSCKQLIVCSLAAILLLIPSVSFAADSNISVKLLNYIGNKSSI SLSPTGFYKVTGDNVAVTDRFAGASRYETATLASNSQWKNPNTVILVNRDIFIDALPV IPLAKKLNAPVLFTQPDTLTKTTERQIAKFNPDNILIIGGARSISKDVENKLKSYGAV KRISGKNRYVLSENIAKQMGSYDKAIVVTGRVFQDALAIAPYAAAHGYPILLTEKDKL PDYDLPKQVIIIGSSFSVSDSVENQIKKTSTVQRIPGSTRYELTANIIKQLKLKADKV VMTNGTKYADVLIGASLASKKNSQILFVKQDSVPAAAKSITKDKATYAYDFIGSTSSI SAEVENSLADEFYLADGGTYNLKINSGKLNLENIKTYGNSLRIKPENYSTSNRISLDG KQYLGTVNFSIESTKYIRPVNENIPFEDYLKGVIPNEMPASWSLEALKAQTVAARTYS ITKTGTTVPDTTAFQVYGGYSWNSNTNKAVEQTKGKVLKYNGSLITAAYSSSNGGYTE ASNEVWSSSVPYLIAKKDTKDPQIGWTLTLSKQQLDTKSLDLTKPSSWWSSATETDSA RLSGVKNWILKNKETSADSVKIASIDDLSFSGTTQGQRAKTASMKVKYFVKSSTGSYN LSKITTISVPTSELRTMIGATVFKSTYVTVKKDTSKYTISGKGYGHGIGMSQYGAKAR AEAGDSYSSILKFYYPGTTLTSY*" gene complement(3526246..3528363) /gene="lytB" /locus_tag="BSU_35630" /old_locus_tag="BSU35630" CDS complement(3528387..3528695) /gene="lytA" /locus_tag="BSU_35640" /old_locus_tag="BSU35640" /function="16.13: Shape" /function="16.11: Scavenge (Catabolism)" /function="16.1: Circulate" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:1357079, 10974124, 22720735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1357079, 10974124, 22720735; Product type lp: lipoprotein" /codon_start=1 /transl_table=11 /product="membrane bound lipoprotein" /protein_id="NP_391444.1" /db_xref="EnsemblGenomes-Gn:BSU35640" /db_xref="EnsemblGenomes-Tr:CAB15581" /db_xref="GOA:Q02112" /db_xref="SubtiList:BG10405" /db_xref="UniProtKB/Swiss-Prot:Q02112" /translation="MKKFIALLFFILLLSGCGVNSQKSQGEDVSPDSNIETKEGTYVG LADTHTIEVTVDNEPVSLDITEESTSDLDKFNSGDKVTITYEKNDEGQLLLKDIERAN *" gene complement(3528387..3528695) /gene="lytA" /locus_tag="BSU_35640" /old_locus_tag="BSU35640" downshifts 3528601 /Source="Nicolas_upshifts" /id="D1841" /incds=1 /nref=1 /ntot=45 /MaxReadThrough="1.03108" /MaxDrop="2.46089" /score="-4.93783022" /energy="-8" /TU="NA" /idTUdmin="U2787" /TUdmin="-198" /isTUend="FALSE" promotor_-35 3528691..3528695 /Source="Nicolas_upshift_promotors" /id="U2787" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.998001998001998" /psig=0 /xcortree=300 /SigmaFactorBS="cgaaagaagcaatataaagaacagtaaagcaataaattttTT CATttttttcaCCTCATTATATTTTAtcgtcaacctattttatattttaaagaaaaat t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3528704..3528718 /Source="Nicolas_upshift_promotors" /id="U2787" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.998001998001998" /psig=0 /xcortree=300 /SigmaFactorBS="cgaaagaagcaatataaagaacagtaaagcaataaattttTT CATttttttcaCCTCATTATATTTTAtcgtcaacctattttatattttaaagaaaaat t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-10 complement(3528705..3528723) /Source="Nicolas_upshift_promotors" /id="U2788" /multdbtbs="SigA,SigD" /comp="M10" /sig="SigD" /pcomp="0.925074925074925" /psig="0.925074925074925" /xcortree=2795 /SigmaFactorBS="gaaatcctaaaatagtcgttttttataaaaaaaagtttcatt gtttcttaatttttCTTTAAAAtataaaataggttGACGATAAAATATAATGAGgtga a" /listShort="lytA, lytB, lytC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3528711 /Source="Nicolas_upshifts" /id="U2787" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.998001998001998" /psig=0 /xcortree=300 /SigmaFactorBS="cgaaagaagcaatataaagaacagtaaagcaataaattttTT CATttttttcaCCTCATTATATTTTAtcgtcaacctattttatattttaaagaaaaat t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(3528737..3528744) /Source="Nicolas_upshift_promotors" /id="U2788" /multdbtbs="SigA,SigD" /comp="M10" /sig="SigD" /pcomp="0.925074925074925" /psig="0.925074925074925" /xcortree=2795 /SigmaFactorBS="gaaatcctaaaatagtcgttttttataaaaaaaagtttcatt gtttcttaatttttCTTTAAAAtataaaataggttGACGATAAAATATAATGAGgtga a" /listShort="lytA, lytB, lytC" /GFF_Attribute="listLong" /label="promotor_-35" upshifts complement(3528740) /Source="Nicolas_upshifts" /id="U2788" /multdbtbs="SigA,SigD" /comp="M10" /sig="SigD" /pcomp="0.925074925074925" /psig="0.925074925074925" /xcortree=2795 /SigmaFactorBS="gaaatcctaaaatagtcgttttttataaaaaaaagtttcatt gtttcttaatttttCTTTAAAAtataaaataggttGACGATAAAATATAATGAGgtga a" /listShort="lytA, lytB, lytC" /GFF_Attribute="listLong" promotor_-35 3528761..3528769 /Source="Nicolas_upshift_promotors" /id="U2789" /multdbtbs="SigX" /comp="M9" /sig="SigWXY" /pcomp="0.584415584415584" /psig="0.584415584415584" /xcortree=2152 /SigmaFactorBS="aaagaaaaattaagaaacaaTGAAACTTTtttttataaaaaa CGACTATTTTAGGAtttcattcttgtattaaatagagttgtatttattggaaatttaa c" /listShort="lytR" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3528783..3528796 /Source="Nicolas_upshift_promotors" /id="U2789" /multdbtbs="SigX" /comp="M9" /sig="SigWXY" /pcomp="0.584415584415584" /psig="0.584415584415584" /xcortree=2152 /SigmaFactorBS="aaagaaaaattaagaaacaaTGAAACTTTtttttataaaaaa CGACTATTTTAGGAtttcattcttgtattaaatagagttgtatttattggaaatttaa c" /listShort="lytR" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3528801 /Source="Nicolas_upshifts" /id="U2789" /multdbtbs="SigX" /comp="M9" /sig="SigWXY" /pcomp="0.584415584415584" /psig="0.584415584415584" /xcortree=2152 /SigmaFactorBS="aaagaaaaattaagaaacaaTGAAACTTTtttttataaaaaa CGACTATTTTAGGAtttcattcttgtattaaatagagttgtatttattggaaatttaa c" /listShort="lytR" /GFF_Attribute="listLong" CDS 3528879..3529799 /gene="tagU" /locus_tag="BSU_35650" /old_locus_tag="BSU35650" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:1357079, 9636707, 12034833, 19099556, 28197687, 29107701" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1357079, 9636707, 12034833, 19099556, 28197687, 29107701; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="teichoic acid-peptidoglycan tethering enzyme (LCP component) with transcription regulator domain of major autolysin expression" /protein_id="NP_391445.1" /db_xref="EnsemblGenomes-Gn:BSU35650" /db_xref="EnsemblGenomes-Tr:CAB15582" /db_xref="GOA:Q02115" /db_xref="InterPro:IPR004474" /db_xref="InterPro:IPR023734" /db_xref="SubtiList:BG10404" /db_xref="UniProtKB/Swiss-Prot:Q02115" /translation="MRNERRKKKKTLLLTILTIIGLLVLGTGGYAYYLWHKAASTVAS IHESIDKSKKRDKEVSINKKDPFSVLIMGVDERDGDKGRADTLIYMTVNPKTNTTDMV SIPRDTYTKIIGKGTMDKINHSYAFGGTQMTVDTVENFLDVPVDYFVKVNMESFRDVV DTLGGITVNSTFAFSYDGYSFGKGEITLNGKEALAYTRMRKEDPRGDFGRQDRQRQVI QGIINKGANISSITKFGDMFKVVENNVKTNLTFDNMWDIQSDYKGARKHIKQHELKGT GTKINGIYYYQADESALSDITKELKESLEK*" gene 3528879..3529799 /gene="tagU" /locus_tag="BSU_35650" /old_locus_tag="BSU35650" downshifts 3529789 /Source="Nicolas_upshifts" /id="D1842" /incds=0 /nref=224 /ntot=261 /MaxReadThrough="0.434639999999999" /MaxDrop="6.11301" /score="-4.93783022" /energy="-8" /TU="NA" /idTUdmin="U2789" /TUdmin=0 /isTUend="TRUE" CDS complement(3529839..3530981) /gene="mnaA" /locus_tag="BSU_35660" /old_locus_tag="BSU35660" /EC_number="5.1.3.14" /function="16.8: Protect" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:12107153, 16952950" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12107153, 16952950; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="UDP-N-acetylmannosamine 2-epimerase" /protein_id="NP_391446.1" /db_xref="EnsemblGenomes-Gn:BSU35660" /db_xref="EnsemblGenomes-Tr:CAB15583" /db_xref="GOA:P39131" /db_xref="InterPro:IPR003331" /db_xref="InterPro:IPR029767" /db_xref="PDB:1O6C" /db_xref="PDB:4FKZ" /db_xref="SubtiList:BG10403" /db_xref="UniProtKB/Swiss-Prot:P39131" /translation="MKKLKVMTVFGTRPEAIKMAPLVLELKKYPEIDSYVTVTAQHRQ MLDQVLDAFHIKPDFDLNIMKERQTLAEITSNALVRLDELFKDIKPDIVLVHGDTTTT FAGSLAAFYHQIAVGHVEAGLRTGNKYSPFPEELNRQMTGAIADLHFAPTGQAKDNLL KENKKADSIFVTGNTAIDALNTTVRDGYSHPVLDQVGEDKMILLTAHRRENLGEPMEN MFKAIRRIVGEFEDVQVVYPVHLNPVVREAAHKHFGDSDRVHLIEPLEVIDFHNFAAK SHFILTDSGGVQEEAPSLGKPVLVLRDTTERPEGVEAGTLKLAGTDEENIYQLAKQLL TDPDEYKKMSQASNPYGDGEASRRIVEELLFHYGYRKEQPDSFTGK*" gene complement(3529839..3530981) /gene="mnaA" /locus_tag="BSU_35660" /old_locus_tag="BSU35660" downshifts complement(3529863) /Source="Nicolas_upshifts" /id="D1843" /incds=0 /nref=126 /ntot=236 /MaxReadThrough="0.41249" /MaxDrop="5.56107" /score="7.64930656" /energy="-11" /TU="NA" /idTUdmin="U2790" /TUdmin="-20" /isTUend="TRUE" promotor_-10 complement(3531020..3531039) /Source="Nicolas_upshift_promotors" /id="U2790" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.984015984015984" /psig=1 /xcortree=1891 /SigmaFactorBS="aaaacttatatcattttatttgaatcaagaatgaaatGATTt aaaatgatgcattTTCATGTAGAATATGTAGTAtgaatttatttactatagcagaaaa c" /listShort="mnaA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3531034) /Source="Nicolas_upshifts" /id="U2790" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.984015984015984" /psig=1 /xcortree=1891 /SigmaFactorBS="aaaacttatatcattttatttgaatcaagaatgaaatGATTt aaaatgatgcattTTCATGTAGAATATGTAGTAtgaatttatttactatagcagaaaa c" /listShort="mnaA" /GFF_Attribute="listLong" promotor_-35 complement(3531054..3531057) /Source="Nicolas_upshift_promotors" /id="U2790" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.984015984015984" /psig=1 /xcortree=1891 /SigmaFactorBS="aaaacttatatcattttatttgaatcaagaatgaaatGATTt aaaatgatgcattTTCATGTAGAATATGTAGTAtgaatttatttactatagcagaaaa c" /listShort="mnaA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 3531110..3531114 /Source="Nicolas_upshift_promotors" /id="U2791" /multdbtbs="SigA" /comp="M16" /sig="SigA" /pcomp="0.494505494505495" /psig="0.998001998001998" /xcortree=96 /SigmaFactorBS="tcaaataaaatgatataagttttaatattaaggataaaGCTT GtttaaaaatggtttaTCCGATATCATAAAAATGTGtaaaaacatattgaaaagggta a" /listShort="S1362, gtaB, S1363" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3531130..3531149 /Source="Nicolas_upshift_promotors" /id="U2791" /multdbtbs="SigA" /comp="M16" /sig="SigA" /pcomp="0.494505494505495" /psig="0.998001998001998" /xcortree=96 /SigmaFactorBS="tcaaataaaatgatataagttttaatattaaggataaaGCTT GtttaaaaatggtttaTCCGATATCATAAAAATGTGtaaaaacatattgaaaagggta a" /listShort="S1362, gtaB, S1363" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 3531131..3531226 /Source="Nicolas_S_feature" /locus_tag="new_3665533_3665628" /HighExp="C90, dia5, Salt, Lbexp, T1.0H, MG 5, GM 90, MG 45, LoTm, T3.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.998" /TUlongSig="NA" /TUlongPSig="NA" /label="S1362" upshifts 3531132 /Source="Nicolas_upshifts" /id="U2791" /multdbtbs="SigA" /comp="M16" /sig="SigA" /pcomp="0.494505494505495" /psig="0.998001998001998" /xcortree=96 /SigmaFactorBS="tcaaataaaatgatataagttttaatattaaggataaaGCTT GtttaaaaatggtttaTCCGATATCATAAAAATGTGtaaaaacatattgaaaagggta a" /listShort="S1362, gtaB, S1363" /GFF_Attribute="listLong" CDS 3531227..3532105 /gene="gtaB" /locus_tag="BSU_35670" /old_locus_tag="BSU35670" /EC_number="2.7.7.9" /function="16.8: Protect" /function="16.13: Shape" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:2846750, 8126437, 8320212, 9658024, 17662947, 26735940" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 2846750, 8126437, 8320212, 9658024, 17662947, 26735940; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="UTP-glucose-1-phosphate uridylyltransferase" /protein_id="NP_391447.1" /db_xref="EnsemblGenomes-Gn:BSU35670" /db_xref="EnsemblGenomes-Tr:CAB15584" /db_xref="GOA:Q05852" /db_xref="InterPro:IPR005771" /db_xref="InterPro:IPR005835" /db_xref="InterPro:IPR029044" /db_xref="SubtiList:BG10402" /db_xref="UniProtKB/Swiss-Prot:Q05852" /translation="MKKVRKAIIPAAGLGTRFLPATKAMPKEMLPIVDKPTIQYIIEE AVEAGIEDIIIVTGKSKRAIEDHFDYSPELERNLEEKGKTELLEKVKKASNLADIHYI RQKEPKGLGHAVWCARNFIGDEPFAVLLGDDIVQAETPGLRQLMDEYEKTLSSIIGVQ QVPEEETHRYGIIDPLTSEGRRYQVKNFVEKPPKGTAPSNLAILGRYVFTPEIFMYLE EQQVGAGGEIQLTDAIQKLNEIQRVFAYDFEGKRYDVGEKLGFITTTLEFAMQDKELR DQLVPFMEGLLNKEEI*" gene 3531227..3532105 /gene="gtaB" /locus_tag="BSU_35670" /old_locus_tag="BSU35670" S_feature 3532106..3533197 /Source="Nicolas_S_feature" /locus_tag="new_3666508_3667599" /HighExp="Etha, Gly, C30, M9-stat, B60, T1.30H, B36, T1.0H, M40t90, T0.30H" /AntisenseName="yvzH" /AntisenseCor="-0.24043295548020899" /AntisenseRegPval="-4.2" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.998" /TUlongSig="NA" /TUlongPSig="NA" /label="S1363" S_feature complement(3532175..3532530) /Source="Nicolas_S_feature" /locus_tag="new_3666577_3666932_c" /HighExp="C30, LPh, HPh, Gly, G135, HiOs, aero, GM 25, MG 25, GM-0.1" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.74940200000000001" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="SigD" /TUlongPSig="0.996" /label="S1364" CDS 3532439..3532657 /locus_tag="BSU_35678" /old_locus_tag="BSU35678" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function; PubMedId: 7704262" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_009514004.1" /translation="MATILIPLTTLLDLSRIVGLIENHGIKPASIQTIKGTSPIPVMT SLLLRIPNTNQYAIIRIRGFKTCHNTPK*" gene 3532439..3532657 /locus_tag="BSU_35678" /old_locus_tag="BSU35678" CDS complement(3532531..3532614) /gene="yvzH" /locus_tag="BSU_35679" /old_locus_tag="BSU35679" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function; PubMedId: 7704262; Product type e: enzyme" /pseudo /codon_start=1 /transl_table=11 /product="putative teichoic acid translocation permease protein tagG (fragment)" /db_xref="PSEUDO:CAX52700.1" /translation="MMAYWFVFGMRNSKLVITGIGEVPFIV*" gene complement(3532531..3532614) /gene="yvzH" /locus_tag="BSU_35679" /old_locus_tag="BSU35679" /pseudo S_feature complement(3532615..3532806) /Source="Nicolas_S_feature" /locus_tag="new_3667017_3667208_c" /HighExp="HPh, LPh, C30, Gly, S0, HiOs, aero, G135, Mal, BMM" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigD" /TUshortPSig="1, 0.996" /TUlongSig="NA" /TUlongPSig="NA" /label="S1365" CDS complement(3532807..3535509) /gene="ggaB" /locus_tag="BSU_35680" /old_locus_tag="BSU35680" /function="16.8: Protect" /function="16.13: Shape" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:16735734" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16735734; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="poly(glucosyl N-acetylgalactosamine 1-phosphate)glucosyltransferase" /protein_id="NP_391448.1" /db_xref="EnsemblGenomes-Gn:BSU35680" /db_xref="EnsemblGenomes-Tr:CAB15585" /db_xref="GOA:P46918" /db_xref="InterPro:IPR001173" /db_xref="InterPro:IPR007554" /db_xref="InterPro:IPR029044" /db_xref="SubtiList:BG11192" /db_xref="UniProtKB/Swiss-Prot:P46918" /translation="MNEKSFNYDFSVIMPIYNVELYLTEAIESIINQTIGFENIQLIL VNDDSPDKSEIICKEYAQKYPNNIVYAKKQNGGVSSARNYGLKYAEGRYIQFLDPDDL VSEGTFENVLNFFDEHKNEIDIVAIPIFFAEGRTGEHNLNNKFSSTRILDVEKEPHHI LTHCCSTFIKKDALKNIRFDENCKIGEDAKLVNLIISQKKKYGLVKEAKYHYRVREDG SSAMQTAKANKNWFNHSLITFSKNLIDIIKNHEQKIPLFLQYMVMHDLKWKLLIKDIS ETPLDENEYSEFLTLIREVLSYIDDDVIIETKSVSHFYLYHALKIKHGENYSRYVYER ETEQDYYLYREGKIVSKLSDQTLTIEILEENEDSIHIEGFWSSLFNSKGFKFYAKIGE TKIKAKNIKRQHNDYISLGEVIKKYPGFSIDIPKGHLADNHHIEFFITKGKKRKLTKL RFFKYSGLSNDLYNTYVAKKDYIFYYNYKKLMFKKNNFKNRFIKEFRFLKSLHKSGEK SKKRKSAIKKALMARMVHHVFTIFNRKPVWLFIDRQDKADDNAEHLFKYAINKNDGVK KYFIIKKDSKDYDRIKKYGKVIPYRSFRHKILTLSSSKVISTHADIWVVNPFFNMEIY FRDLFNFEFIFLQHGITMADHSEWLNKYNKNIKLLVTSAKPEYRSIVKGNYNYKKENI LLGGFPRYDNLKKSEGEKQLLIMPTWRKDIVLPKDQAKGVRPYNPKFKDSEYFSRYNA LINDERLIEFAKKNNYKITFFPHPDIQQQIVDFEKHDYVEFADYNSSYQMLFNSSNIM ITDFSSVAFDFAYEKKPVIYYQYEKSYHFKLDYYDYKKMGFGDVLENHNSLVDKVIYY MKNNSRMEDKYRKRVDNFFAYTDKNNRNRIYNAILELDNNKVAK*" gene complement(3532807..3535509) /gene="ggaB" /locus_tag="BSU_35680" /old_locus_tag="BSU35680" S_feature complement(3535510..3535632) /Source="Nicolas_S_feature" /locus_tag="new_3669912_3670034_c" /HighExp="BMM, HiOs, MG 15, C30, SMM, GM 90, HPh, MG 150, MG 25, G135" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigD" /TUshortPSig="1, 0.996" /TUlongSig="NA" /TUlongPSig="NA" /label="S1366" promotor_-35 3535531..3535537 /Source="Nicolas_upshift_promotors" /id="U2792" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=207 /SigmaFactorBS="ttttttcgttcataaaagattactcctaacataaTGTTTATa tgaataagaattcGGGTAAATAAAATTAAGAAacaagagagtactaatttttgcaaaa c" /listShort="S1367, S1370, yvzE" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3535552..3535570 /Source="Nicolas_upshift_promotors" /id="U2792" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=207 /SigmaFactorBS="ttttttcgttcataaaagattactcctaacataaTGTTTATa tgaataagaattcGGGTAAATAAAATTAAGAAacaagagagtactaatttttgcaaaa c" /listShort="S1367, S1370, yvzE" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 3535557..3538389 /Source="Nicolas_S_feature" /locus_tag="new_3669959_3672791" /HighExp="Sw, LoTm, M9-stat, Salt, B60, T0.30H, Gly, T1.0H, B36, BI" /AntisenseName="ggaA" /AntisenseCor="-0.503651102561819" /AntisenseRegPval="-18" /CDS_PredictionProba="NA" /TUshortSig="SigB" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1367" upshifts 3535557 /Source="Nicolas_upshifts" /id="U2792" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=207 /SigmaFactorBS="ttttttcgttcataaaagattactcctaacataaTGTTTATa tgaataagaattcGGGTAAATAAAATTAAGAAacaagagagtactaatttttgcaaaa c" /listShort="S1367, S1370, yvzE" /GFF_Attribute="listLong" CDS complement(3535633..3536973) /gene="ggaA" /locus_tag="BSU_35690" /old_locus_tag="BSU35690" /function="16.5: Explore" /function="16.8: Protect" /function="16.13: Shape" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 16735734, 7704262; Product type e: enzyme" /pseudo /codon_start=1 /transl_table=11 /product="poly(glucosyl N-acetylgalactosamine 1-phosphate)glucosyltransferase (missing signal peptide)" /db_xref="EnsemblGenomes-Gn:BSU35690" /db_xref="EnsemblGenomes-Tr:CAB15586" /db_xref="GOA:P46917" /db_xref="InterPro:IPR001173" /db_xref="InterPro:IPR029044" /db_xref="PSEUDO:CAB15586.1" /db_xref="SubtiList:BG11367" /db_xref="UniProtKB/Swiss-Prot:P46917" /translation="MFSIIIPIYNSENYLRYSIESVLNQSIGFKENIELILIDDGSVD SSPQICESFKNLYPNNIKIMKIENSGPSAARNCGLSNVSERSKFIGFLDSDDAFSQNA LQSVYDFFCDSEHVNIAVLPVYYTGEKEGGHKLNNRFEKGTRVINILNDYKAIHFYIG GTFYRRHTLTSTVLFDESIKFWEDAIFFNQLLLKEKRYGAVAEGKYFYRKRKEQDSLV DRSWFNKKRYTYLLNECYMTLLMDSFNKYDIVLPYLQFLIVYHIKLFLYPNYRDVYKS VLDQQEQRVFVDDFIKVLKFIDPQFIKEQDMPMYYKEFMFHLLKENTEALENIKKERV LHSSCTVTSAKIKGLRLELTGHFINQYYEMKENDRIYIKYFKRLKKCKRKELKKTIEV WGYKLRDFRYAGFVVEIPIWAFAFDFVLKTPNDSLELNHVNIFKSLLTRVFKKR*" gene complement(3535633..3536973) /gene="ggaA" /locus_tag="BSU_35690" /old_locus_tag="BSU35690" /pseudo CDS complement(3537014..3537220) /gene="yvzI" /locus_tag="BSU_35698" /old_locus_tag="BSU35698" /EC_number="2.7.8.12" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function; PubMedId: 7704262; Product type e: enzyme" /pseudo /codon_start=1 /transl_table=11 /product="putative CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase (fragment)" /db_xref="PSEUDO:CAX52701.1" /translation="MYDLPAYRDCIRGFYFNFQQKTPGNLLQTSEELIDTVKELLHNP YIDHNYEDFYNKFCNLEEARLLKE*" gene complement(3537014..3537220) /gene="yvzI" /locus_tag="BSU_35698" /old_locus_tag="BSU35698" /pseudo S_feature complement(3537221..3538094) /Source="Nicolas_S_feature" /locus_tag="new_3671623_3672496_c" /HighExp="HiOs, Heat, BMM, MG 15, GM 90, MG 25, MG 150, C30, GM 25, MG 90" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.99943499999999996" /TUshortSig="SigA, SigD" /TUshortPSig="1, 0.996" /TUlongSig="NA" /TUlongPSig="NA" /label="S1368" promotor_-10 complement(3538088..3538107) /Source="Nicolas_upshift_promotors" /id="U2793" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.55044955044955" /psig=1 /xcortree=3053 /SigmaFactorBS="gtgctgatgatttacatttttaaagagcCTTAACTtttatag gaacaTATGCTATTATTGTTTATTAttaatggaacgtaaaaaatatgtcgaaatgata a" /listShort="S1368, yvzI, ggaA, S1366, ggaB, S1365, yvzH, S1364" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3538094) /Source="Nicolas_upshifts" /id="U2793" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.55044955044955" /psig=1 /xcortree=3053 /SigmaFactorBS="gtgctgatgatttacatttttaaagagcCTTAACTtttatag gaacaTATGCTATTATTGTTTATTAttaatggaacgtaaaaaatatgtcgaaatgata a" /listShort="S1368, yvzI, ggaA, S1366, ggaB, S1365, yvzH, S1364" /GFF_Attribute="listLong" S_feature complement(3538096..3538335) /Source="Nicolas_S_feature" /locus_tag="new_3672498_3672737_c" /HighExp="Cold, LBGstat, C30, GM 25, GM 15, GM 45, GM 60, GM 10, GM-0.2, GM 90" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigD" /TUshortPSig="0.996" /TUlongSig="NA" /TUlongPSig="NA" /label="S1369" promotor_-35 complement(3538120..3538126) /Source="Nicolas_upshift_promotors" /id="U2793" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.55044955044955" /psig=1 /xcortree=3053 /SigmaFactorBS="gtgctgatgatttacatttttaaagagcCTTAACTtttatag gaacaTATGCTATTATTGTTTATTAttaatggaacgtaaaaaatatgtcgaaatgata a" /listShort="S1368, yvzI, ggaA, S1366, ggaB, S1365, yvzH, S1364" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(3538317..3538335) /Source="Nicolas_upshift_promotors" /id="U2794" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp="0.996003996003996" /psig="0.996003996003996" /xcortree=2827 /SigmaFactorBS="ttcactaaattttaccacgaaaatttttaggaactacgtATT ACAATtccttcacgttttGACGATGAAGTAATATGAGgagggcgtacaaaataaatga c" /listShort="S1369, S1368, yvzI, ggaA, S1366, ggaB, S1365, yvzH" /listLong="S1364" /label="promotor_-10" upshifts complement(3538335) /Source="Nicolas_upshifts" /id="U2794" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp="0.996003996003996" /psig="0.996003996003996" /xcortree=2827 /SigmaFactorBS="ttcactaaattttaccacgaaaatttttaggaactacgtATT ACAATtccttcacgttttGACGATGAAGTAATATGAGgagggcgtacaaaataaatga c" /listShort="S1369, S1368, yvzI, ggaA, S1366, ggaB, S1365, yvzH" /listLong="S1364" promotor_-35 complement(3538349..3538356) /Source="Nicolas_upshift_promotors" /id="U2794" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp="0.996003996003996" /psig="0.996003996003996" /xcortree=2827 /SigmaFactorBS="ttcactaaattttaccacgaaaatttttaggaactacgtATT ACAATtccttcacgttttGACGATGAAGTAATATGAGgagggcgtacaaaataaatga c" /listShort="S1369, S1368, yvzI, ggaA, S1366, ggaB, S1365, yvzH" /listLong="S1364" /label="promotor_-35" promotor_-35 3538358..3538365 /Source="Nicolas_upshift_promotors" /id="U2795" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.993006993006993" /psig=1 /xcortree=2179 /SigmaFactorBS="tcgtcaaaacgtgaaggaattgtaataCGTAGTTCctaaaaa ttttCGTGGTAAAATTTAGTGAAGtctttatcaggctaagggactttatctaaactac g" /listShort="S1370, yvzE" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3538377..3538396 /Source="Nicolas_upshift_promotors" /id="U2795" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.993006993006993" /psig=1 /xcortree=2179 /SigmaFactorBS="tcgtcaaaacgtgaaggaattgtaataCGTAGTTCctaaaaa ttttCGTGGTAAAATTTAGTGAAGtctttatcaggctaagggactttatctaaactac g" /listShort="S1370, yvzE" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 3538391..3538521 /Source="Nicolas_S_feature" /locus_tag="new_3672793_3672923" /HighExp="Sw, T0.30H, LoTm, B60, T1.0H, Lbtran, C30, LBGtran, dia5, dia15" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigB" /TUshortPSig="1, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S1370" upshifts 3538391 /Source="Nicolas_upshifts" /id="U2795" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.993006993006993" /psig=1 /xcortree=2179 /SigmaFactorBS="tcgtcaaaacgtgaaggaattgtaataCGTAGTTCctaaaaa ttttCGTGGTAAAATTTAGTGAAGtctttatcaggctaagggactttatctaaactac g" /listShort="S1370, yvzE" /GFF_Attribute="listLong" promotor_no_box 3538463..3538563 /Source="Nicolas_upshift_promotors" /id="U2796" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.711288711288711" /psig="0.104895104895105" /xcortree=14 /SigmaFactorBS="agggttgatatgatataaacgaaaatcaattagataaaggaa aaactgaacacttctgaaaaaagtgataagtttctttcactatatcctccaaaaagaa c" /listShort="yvzE" /GFF_Attribute="listLong" /label="promotor_no_box" upshifts 3538523 /Source="Nicolas_upshifts" /id="U2796" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.711288711288711" /psig="0.104895104895105" /xcortree=14 /SigmaFactorBS="agggttgatatgatataaacgaaaatcaattagataaaggaa aaactgaacacttctgaaaaaagtgataagtttctttcactatatcctccaaaaagaa c" /listShort="yvzE" /GFF_Attribute="listLong" CDS 3538527..3539123 /gene="yvzE" /locus_tag="BSU_35699" /old_locus_tag="BSU35699" /EC_number="2.7.7.9" /function="16.13: Shape" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function; Product type e : enzyme" /pseudo /codon_start=1 /transl_table=11 /product="putative UTP-glucose-1-phosphate uridylyltransferase (UDP-glucose pyrophosphorylase) (UDPGP) (fragment)" /db_xref="PSEUDO:CAX52702.1" /translation="MISFFHYILQKEPKGLGHAVWFAPNFIGDEPFAFLLGDDIVQAD TPGLRQLTDEYERTLSSIIGVQQVPEDETHCYGIIAPLTSEGRRYQVKNFIEKPPKDT APSNLAILGRYVFTPEIFMYLEEQQVGAGGEIQLTDAIQKLNEIQRVFAYDFEGKRYD VGEKLGFITTTLEFAMQDKELRDQLVPFMEGLLNKEEI*" gene 3538527..3539123 /gene="yvzE" /locus_tag="BSU_35699" /old_locus_tag="BSU35699" /pseudo downshifts 3538721 /Source="Nicolas_upshifts" /id="D1844" /incds=1 /nref=94 /ntot=183 /MaxReadThrough="4.62614" /MaxDrop="5.15039" /score="34.2325445" /energy="-14.3" /TU="U2792,U2795" /idTUdmin="U2796" /TUdmin=0 /isTUend="TRUE" CDS complement(3539162..3540745) /gene="tagH" /locus_tag="BSU_35700" /old_locus_tag="BSU35700" /EC_number="3.6.3.40" /function="16.1: Circulate" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 7565096, 12682299, 17012386, 18156271; Product type t: transporter" /codon_start=1 /transl_table=11 /product="ATP-binding teichoic acid precursor transporter component" /protein_id="NP_391451.1" /db_xref="EnsemblGenomes-Gn:BSU35700" /db_xref="EnsemblGenomes-Tr:CAB15587" /db_xref="GOA:P42954" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR015860" /db_xref="InterPro:IPR017871" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR030284" /db_xref="SubtiList:BG11191" /db_xref="UniProtKB/Swiss-Prot:P42954" /translation="MKLKVSFRNVSKQYHLYKKQSDKIKGLFFPAKDNGFFAVRNVSF DVYEGETIGFVGINGSGKSTMSNLLAKIIPPTSGEIEMNGQPSLIAIAAGLNNQLTGR DNVRLKCLMMGLTNKEIDDMYDSIVEFAEIGDFINQPVKNYSSGMKSRLGFAISVHID PDILIIDEALSVGDQTFYQKCVDRINEFKKQGKTIFFVSHSIGQIEKMCDRVAWMHYG ELRMFDETKTVVKEYKAFIDWFNKLSKKEKETYKKEQTEERKKEDPEAFARFRKKKKK PKSLANAIQIAILSILTVFMAGTMFFNAPLRTIASFGAIPQNEVKNHHGDAKGKSEER LTAINKQGFIANEKAAAYKDQGLKQKADVTLPFGTKVTVAAKGKQAAKIKFDGHSYYV KQSAVATNMKHAELHATAFTSYVSQNAASSYEYFLKFLGDSSTSIQSKLNGYTEGNKA DGRKTLNFDYEKISYVLENDKATELIFHNISPINPASLSLSDSDVLYDSSKKRFLVNT DDQVFAVDNEEHTLTLMLK*" gene complement(3539162..3540745) /gene="tagH" /locus_tag="BSU_35700" /old_locus_tag="BSU35700" downshifts 3539205 /Source="Nicolas_upshifts" /id="D1845" /incds=0 /nref=2 /ntot=19 /MaxReadThrough="1.20059" /MaxDrop="5.25978" /score="34.2325445" /energy="-14.3" /TU="NA" /idTUdmin="U2792" /TUdmin=440 /isTUend="FALSE" CDS complement(3540765..3541592) /gene="tagG" /locus_tag="BSU_35710" /old_locus_tag="BSU35710" /function="16.8: Protect" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 7565096, 12682299, 15849754, 16850406, 17012386, 18156271, 27213893; Product type t: transporter" /codon_start=1 /transl_table=11 /product="teichoic acid precursors permease" /protein_id="NP_391452.1" /db_xref="EnsemblGenomes-Gn:BSU35710" /db_xref="EnsemblGenomes-Tr:CAB15588" /db_xref="GOA:P42953" /db_xref="InterPro:IPR000412" /db_xref="InterPro:IPR013525" /db_xref="SubtiList:BG11205" /db_xref="UniProtKB/Swiss-Prot:P42953" /translation="MNDLLRILREQITSFPLILRLAAYETKSKYQMNYLGVLWQFLNP LIQMLAYWFVFGMGIRKGGPVTTGAGEVPFIIWMLAGLIPWFFISPTILDGSNSVFKR INMVAKMNFPISSLPSVAIASNLFSYMIMMVIYIIVLLVNGVFPSVHWLQYIYYFICM IAFMFSFSLFNSTISVLIRDYQFLLQAVTRLLFFLLPIFWDVNAKLGQSHPELVPVLK LNPLFYIIEGFRNSFLDGAWFFHDMKYTLYFWLFTFLLLLVGSILHMKFRDKFVDFL* " gene complement(3540765..3541592) /gene="tagG" /locus_tag="BSU_35710" /old_locus_tag="BSU35710" S_feature complement(3541593..3541657) /Source="Nicolas_S_feature" /locus_tag="new_3675995_3676059_c" /HighExp="H2O2, LBGstat, dia15, Oxctl, LBGexp, G150, Paraq, G180, G135, dia0" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="0.999, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S1371" promotor_-10 complement(3541653..3541672) /Source="Nicolas_upshift_promotors" /id="U2797" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.93006993006993" /psig="0.999000999001" /xcortree=1823 /SigmaFactorBS="ggcagctttttagatacttgttgagaAGTGaaaaaaaatgca ggaTCTGTTACAATAATCAGCGGtgctttcaaattttaaacagaaagattcccaaaaa c" /listShort="S1371, tagG, tagH" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3541657) /Source="Nicolas_upshifts" /id="U2797" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.93006993006993" /psig="0.999000999001" /xcortree=1823 /SigmaFactorBS="ggcagctttttagatacttgttgagaAGTGaaaaaaaatgca ggaTCTGTTACAATAATCAGCGGtgctttcaaattttaaacagaaagattcccaaaaa c" /listShort="S1371, tagG, tagH" /GFF_Attribute="listLong" S_feature complement(3541659..3541756) /Source="Nicolas_S_feature" /locus_tag="new_3676061_3676158_c" /HighExp="G180, G135, Cold, G150, LPh, S0, Oxctl, Paraq, HPh, C30" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1372" promotor_-35 complement(3541688..3541691) /Source="Nicolas_upshift_promotors" /id="U2797" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.93006993006993" /psig="0.999000999001" /xcortree=1823 /SigmaFactorBS="ggcagctttttagatacttgttgagaAGTGaaaaaaaatgca ggaTCTGTTACAATAATCAGCGGtgctttcaaattttaaacagaaagattcccaaaaa c" /listShort="S1371, tagG, tagH" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3541757..3543997) /gene="tagF" /locus_tag="BSU_35720" /old_locus_tag="BSU35720" /EC_number="2.7.8.12" /function="16.2: Construct biomass (Anabolism)" /function="16.8: Protect" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:12682299, 16141206, 16689786, 17012386, 18723614, 19520862, 20400947" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12682299, 16141206, 16689786, 17012386, 18723614, 19520862, 20400947; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="CDP-glycerol:polyglycerol phosphate glycero-phosphotransferase (poly(glycerol phosphate) polymerase)" /protein_id="NP_391453.1" /db_xref="EnsemblGenomes-Gn:BSU35720" /db_xref="EnsemblGenomes-Tr:CAB15589" /db_xref="GOA:P13485" /db_xref="InterPro:IPR007554" /db_xref="SubtiList:BG10725" /db_xref="UniProtKB/Swiss-Prot:P13485" /translation="MSLVVDTNKRKQKGKSFYTEEQKKVMIENTVIKCILKSLKNNLG SLELLISIDSEHQFLEDYQLFLKLKERRSGTESEFPLQNTGSLEYKTEINAHVLPMPV EMGQTYDFYVEFRKKYEDAEQEPLLKRLSAEVNSIERAFHVDQTTELLILPYTTDKGN FSIKVKREAKIIRFDQIEISSEEISITGYAGYLSSENQYRIKNLNLILKKGGETPIEE KFPIKLERKTHGLENMRADGFVPELYDFEVKVPLKEIPFSNEKRYVYRLFMEYICNDD EGTDIQFNSTALVLGDRKNKLKGLVSIIKTNNAPVRYEVFKKKKKQTLGIRVNDYSLK TRMKYFIKGKKKRLVSKIKKITKMRNKLITKTYKSLFMMASRMPVKRKTVIFESFNGK QYSCNPRAIYEYMRENHPEYKMYWSVNKQYSAPFDEKGIPYINRLSLKWLFAMARAEY WVVNSRLPLWIPKPSHTTYLQTWHGTPLKRLAMDMEEVHMPGTNTKKYKRNFIKEASN WDYLISPNGYSTEIFTRAFQFNKTMIESGYPRNDFLHNDNNEETISLIKSRLNIPRDK KVILYAPTWRDDQFYAKGRYKFDLDLDLHQLRQELGNEYIVILRMHYLVAENFDLGPF EGFAYDFSAYEDIRELYMVSDLLITDYSSVFFDFANLKRPMLFFVPDIETYRDKLRGF YFDFEKEAPGPLVKTTEETIEAIKQISSPDYKLPVSFGPFYDKFCYLESGRSSEKVVN TVFKAE*" gene complement(3541757..3543997) /gene="tagF" /locus_tag="BSU_35720" /old_locus_tag="BSU35720" CDS complement(3543997..3546018) /gene="tagE" /locus_tag="BSU_35730" /old_locus_tag="BSU35730" /EC_number="2.4.1.52" /function="16.8: Protect" /function="16.5: Explore" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:2507871, 9457886, 12682299, 16141206, 16689786, 17012386, 21558268" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 2507871, 9457886, 12682299, 16141206, 16689786, 17012386, 21558268; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="UDP-glucose:polyglycerol phosphate alpha-glucosyltransferase" /protein_id="NP_391454.1" /db_xref="EnsemblGenomes-Gn:BSU35730" /db_xref="EnsemblGenomes-Tr:CAB15590" /db_xref="GOA:P13484" /db_xref="InterPro:IPR001296" /db_xref="InterPro:IPR015397" /db_xref="SubtiList:BG10724" /db_xref="UniProtKB/Swiss-Prot:P13484" /translation="MSLHAVSESNIKQIPDMDYYFISGGLPSNYGGLTKSLLLRSKLF GEECNQNTFFLTFRFDLELSSKIDELYSNGKIDKKFTSVINLFDDFLSVRTNGKRSYE ERIGLDQIKKQVGMGKFAKTLLRLFGKKNNEMSVVYYGDGETIRYVDYWNDKNQLIKR EEYTKNGNLVLVTHYDVQLNKMYLQEYINDQNQVYLDKLYVWNNEEKDVQLSHIIWYS LEGEIKVKDESELRQYWIEYLQKQNDKPKLFLVDSRPQDKHVFKVKKSPSSYYGAIIH NKHYGSNKYQIKGRYKEVFSQMYNLDAVFFITEEQLEDFKLISGEQETFFFTPHTIDK PLDPAVLNVPSEKYKAVIISRLASMKNLIHAVKAFSLVVKEIPEAKLDIFGSGEDFEK IKKEIEDTKLQNNVFLKGYTDNPDSEFQKAWLTISTSHFEGFGLSNMEALSNGCPVVT YDYDYGARSLVTDGANGYVIEQYNIEKLGQAIISLMKDESTHQKFSEQAFKMAEKYSR PNYIENWAFALNQMIEVRIEREKFSKKVGKKDPSISSYTEDFDKTKIEIDIENFDHND IKKIRLVGLDRKNKAEIISTNLQNDQLFVIDLEKDVNIEKIAANKTQVIDFYIVFNAN GHIKTMRRLSSEETKLSGNSIDTNNGYRVEPYTTVKGNFSWRVTEIKES*" gene complement(3543997..3546018) /gene="tagE" /locus_tag="BSU_35730" /old_locus_tag="BSU35730" promotor_-35 3544760..3544769 /Source="Nicolas_upshift_promotors" /id="U2798" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1685 /SigmaFactorBS="gaggttgaaatggttagccaagcttttTGAAACTCTGagtca gggttatCCGTATAGCCTTTCAAaaagacattgttctgcagtttggtatcttcaattt c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3544782..3544797 /Source="Nicolas_upshift_promotors" /id="U2798" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1685 /SigmaFactorBS="gaggttgaaatggttagccaagcttttTGAAACTCTGagtca gggttatCCGTATAGCCTTTCAAaaagacattgttctgcagtttggtatcttcaattt c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3544793 /Source="Nicolas_upshifts" /id="U2798" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1685 /SigmaFactorBS="gaggttgaaatggttagccaagcttttTGAAACTCTGagtca gggttatCCGTATAGCCTTTCAAaaagacattgttctgcagtttggtatcttcaattt c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" S_feature complement(3546019..3546178) /Source="Nicolas_S_feature" /locus_tag="new_3680421_3680580_c" /HighExp="G180, G135, Cold, G150, Oxctl, LBGexp, Paraq, Lbexp, LPhT, LoTm" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1373" CDS complement(3546179..3546568) /gene="tagD" /locus_tag="BSU_35740" /old_locus_tag="BSU35740" /EC_number="2.7.7.39" /function="16.8: Protect" /function="16.5: Explore" /function="16.13: Shape" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:11673441, 12637027, 12637499, 12682299, 16141206, 16689786, 17012386, 21558268" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11673441, 12637027, 12637499, 12682299, 16141206, 16689786, 17012386, 21558268; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="glycerol-3-phosphate cytidylyltransferase" /protein_id="NP_391455.1" /db_xref="EnsemblGenomes-Gn:BSU35740" /db_xref="EnsemblGenomes-Tr:CAB15591" /db_xref="GOA:P27623" /db_xref="InterPro:IPR004821" /db_xref="InterPro:IPR006409" /db_xref="InterPro:IPR014729" /db_xref="PDB:1COZ" /db_xref="PDB:1N1D" /db_xref="SubtiList:BG10449" /db_xref="UniProtKB/Swiss-Prot:P27623" /translation="MKKVITYGTFDLLHWGHIKLLERAKQLGDYLVVAISTDEFNLQK QKKAYHSYEHRKLILETIRYVDEVIPEKNWEQKKQDIIDHNIDVFVMGDDWEGKFDFL KDQCEVVYLPRTEGISTTKIKEEIAGL*" gene complement(3546179..3546568) /gene="tagD" /locus_tag="BSU_35740" /old_locus_tag="BSU35740" S_feature complement(3546569..3546703) /Source="Nicolas_S_feature" /locus_tag="new_3680971_3681105_c" /HighExp="BC, Cold, T3.0H, HiOs, MG-0.2, T1.30H, T3.30H, LPhT, MG 15, T4.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1374" promotor_-10 complement(3546687..3546706) /Source="Nicolas_upshift_promotors" /id="U2799" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.93906093906094" /psig=1 /xcortree=2289 /SigmaFactorBS="taattacatattttggaatgtttttctcctcatgagtacTTA ACCTTttttaggcggTATGCTATAATTAATGATCAgtgaagacatacgagaaatatgt c" /listShort="S1374, tagD, S1373, tagE, tagF, S1372, S1371, tagG, tagH" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3546703) /Source="Nicolas_upshifts" /id="U2799" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.93906093906094" /psig=1 /xcortree=2289 /SigmaFactorBS="taattacatattttggaatgtttttctcctcatgagtacTTA ACCTTttttaggcggTATGCTATAATTAATGATCAgtgaagacatacgagaaatatgt c" /listShort="S1374, tagD, S1373, tagE, tagF, S1372, S1371, tagG, tagH" /GFF_Attribute="listLong" promotor_-35 complement(3546717..3546724) /Source="Nicolas_upshift_promotors" /id="U2799" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.93906093906094" /psig=1 /xcortree=2289 /SigmaFactorBS="taattacatattttggaatgtttttctcctcatgagtacTTA ACCTTttttaggcggTATGCTATAATTAATGATCAgtgaagacatacgagaaatatgt c" /listShort="S1374, tagD, S1373, tagE, tagF, S1372, S1371, tagG, tagH" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 3546858..3546864 /Source="Nicolas_upshift_promotors" /id="U2800" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp=1 /psig=1 /xcortree=2129 /SigmaFactorBS="gtaaaattggaaacatatttaaatttaatgtaaagataatgt tAATCCTTtgttgaagattTATGTTAAAATATAAGGTAGcttgattttgcttttagaa a" /listShort="S1375, tagA, tagB, tagC" /GFF_Attribute="listLong" /label="promotor_-35" S_feature 3546875..3546967 /Source="Nicolas_S_feature" /locus_tag="new_3681277_3681369" /HighExp="B60, LoTm, Cold, T3.30H, T3.0H, Salt, T5.0H, T4.0H, Lbexp, T2.30H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1375" upshifts 3546875 /Source="Nicolas_upshifts" /id="U2800" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp=1 /psig=1 /xcortree=2129 /SigmaFactorBS="gtaaaattggaaacatatttaaatttaatgtaaagataatgt tAATCCTTtgttgaagattTATGTTAAAATATAAGGTAGcttgattttgcttttagaa a" /listShort="S1375, tagA, tagB, tagC" /GFF_Attribute="listLong" promotor_-10 3546876..3546895 /Source="Nicolas_upshift_promotors" /id="U2800" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp=1 /psig=1 /xcortree=2129 /SigmaFactorBS="gtaaaattggaaacatatttaaatttaatgtaaagataatgt tAATCCTTtgttgaagattTATGTTAAAATATAAGGTAGcttgattttgcttttagaa a" /listShort="S1375, tagA, tagB, tagC" /GFF_Attribute="listLong" /label="promotor_-10" CDS 3546968..3547738 /gene="tagA" /locus_tag="BSU_35750" /old_locus_tag="BSU35750" /EC_number="2.4.1.187" /function="16.5: Explore" /function="16.13: Shape" /function="16.2: Construct biomass (Anabolism)" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:12682299, 16141206, 16689786, 16953575, 17012386, 18156271, 19376878" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12682299, 16141206, 16689786, 16953575, 17012386, 18156271, 19376878; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="N-acetylmannosamine (ManNAc) C4 hydroxyl of a membrane-anchored N-acetylglucosaminyl diphospholipid (GlcNAc-pp-undecaprenyl, lipid I) glycosyltransferase" /protein_id="NP_391456.1" /db_xref="EnsemblGenomes-Gn:BSU35750" /db_xref="EnsemblGenomes-Tr:CAB15592" /db_xref="GOA:P27620" /db_xref="InterPro:IPR004629" /db_xref="InterPro:IPR034714" /db_xref="SubtiList:BG10450" /db_xref="UniProtKB/Swiss-Prot:P27620" /translation="MQTETIHNIPYVNSNLTSFIDYLEKHYIDQKIGAVISTVNPEIA FAAIKDRDYFDVLSSSNFILPDGIGVVMMSRLTNNRLQSRIAGYDVFKELLGVANKKK KRIFLYGAKKDVIKGVVSKISSEYPNIKIAGYSDGYVQDRTLVAKQIARANPDMVFVA LGYPHQEKFIHNYRHLFPKAVSIGLGGSFDVFSGNVKRAPSWMIRLNLEWFYRLILNP WRWKRMLSIPKYALTVLKEEKNKKTFYPKPEKDHTKQI*" gene 3546968..3547738 /gene="tagA" /locus_tag="BSU_35750" /old_locus_tag="BSU35750" S_feature complement(3547095..3547443) /Source="Nicolas_S_feature" /locus_tag="new_3681497_3681845_c" /HighExp="S8, S6, S7, S5, S4, G135, S3, C30, G180, ferm" /AntisenseName="tagA" /AntisenseCor="-0.35014495927301897" /AntisenseRegPval="-8.5" /CDS_PredictionProba="NA" /TUshortSig="SigGF" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1376" promotor_-10 complement(3547447..3547458) /Source="Nicolas_upshift_promotors" /id="U2801" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=949 /SigmaFactorBS="atacggctttagggaacaagtgtctgtagttaTGAATGAatt tctcttgatgaGGATACCCTAAAgctacgaataccatgtcaggatttgctcttgcaat t" /listShort="S1376" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3547451) /Source="Nicolas_upshifts" /id="U2801" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=949 /SigmaFactorBS="atacggctttagggaacaagtgtctgtagttaTGAATGAatt tctcttgatgaGGATACCCTAAAgctacgaataccatgtcaggatttgctcttgcaat t" /listShort="S1376" /GFF_Attribute="listLong" promotor_-35 complement(3547473..3547479) /Source="Nicolas_upshift_promotors" /id="U2801" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=949 /SigmaFactorBS="atacggctttagggaacaagtgtctgtagttaTGAATGAatt tctcttgatgaGGATACCCTAAAgctacgaataccatgtcaggatttgctcttgcaat t" /listShort="S1376" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 3547763 /Source="Nicolas_upshifts" /id="D1846" /incds=0 /nref=2 /ntot=103 /MaxReadThrough="6.64821" /MaxDrop="3.225" /score="-6.01444425" /energy="-10.9" /TU="U2800" /idTUdmin="U2800" /TUdmin="-2310" /isTUend="FALSE" CDS 3547771..3548916 /gene="tagB" /locus_tag="BSU_35760" /old_locus_tag="BSU35760" /EC_number="2.7.8.44" /function="16.2: Construct biomass (Anabolism)" /function="16.8: Protect" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:12682299, 16141206, 16150696, 16689786, 17012386, 17660278, 18156271, 18761696" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12682299, 16141206, 16150696, 16689786, 17012386, 17660278, 18156271, 18761696; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="teichoic acid primase, CDP-glycerol:N-acetyl-beta-d-mannosaminyl-1, 4-N-acetyl-d-glucosaminyldiphosphoundecaprenyl glycerophosphotransferase" /protein_id="NP_391457.1" /db_xref="EnsemblGenomes-Gn:BSU35760" /db_xref="EnsemblGenomes-Tr:CAB15593" /db_xref="GOA:P27621" /db_xref="InterPro:IPR007554" /db_xref="SubtiList:BG10451" /db_xref="UniProtKB/Swiss-Prot:P27621" /translation="MKIRSLLANCYLYFLSAIAFFLQWVKPESKVTLLISFEANAKAI LEEYEQGQYSYKLNILYTQQASAIAESFPNVDAYLLQEKNPIHLIKAVYLMFNSKVII TDNYFLLTSVLNKRKQTKCIQVWHANGSLKKFGLEDITNMQRTKTDIKRFQKVYSSYD YLTVGSEEMANIFKKSFGIKDNQLLKIGVPLTDPYYRENKKKISDTLNIQRKKIILYA PTFRDYNMQSIQLPFTEEQLIHQLKEEYVLFVKLHPAIQNNIDIKYSSDYIKDVSNYA LFDLLMAADILITDYSSVPFEFSILNKPILFYTYDLKLYQQKRGLVDNYLSIIPGRAC YDSESLINEIQTPFNYSKIKVFSDRWNKYSDGNSSQNLLNFIENLIS*" gene 3547771..3548916 /gene="tagB" /locus_tag="BSU_35760" /old_locus_tag="BSU35760" downshifts 3548904 /Source="Nicolas_upshifts" /id="D1847" /incds=0 /nref=101 /ntot=235 /MaxReadThrough="3.54908" /MaxDrop="5.95551" /score="-3.22062454" /energy="-10" /TU="U2800" /idTUdmin="U2800" /TUdmin="-1169" /isTUend="FALSE" promotor_-35 3548958..3548965 /Source="Nicolas_upshift_promotors" /id="U2802" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.894105894105894" /psig=1 /xcortree=1505 /SigmaFactorBS="ttcaaaacagaacaagtgttcttttttcTATTGAATaccgaa cgtatgttTGCTTTAATGTAATTAGTTGcttatggcagcaaataataatagaggtggt a" /listShort="tagC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3548980..3548999 /Source="Nicolas_upshift_promotors" /id="U2802" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.894105894105894" /psig=1 /xcortree=1505 /SigmaFactorBS="ttcaaaacagaacaagtgttcttttttcTATTGAATaccgaa cgtatgttTGCTTTAATGTAATTAGTTGcttatggcagcaaataataatagaggtggt a" /listShort="tagC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3548990 /Source="Nicolas_upshifts" /id="U2802" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.894105894105894" /psig=1 /xcortree=1505 /SigmaFactorBS="ttcaaaacagaacaagtgttcttttttcTATTGAATaccgaa cgtatgttTGCTTTAATGTAATTAGTTGcttatggcagcaaataataatagaggtggt a" /listShort="tagC" /GFF_Attribute="listLong" CDS 3549036..3550364 /gene="tagC" /locus_tag="BSU_35770" /old_locus_tag="BSU35770" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 7952180, 16269821; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative polyglycerol phosphate assembly and export protein (teichoic acid biosynthesis)" /protein_id="NP_391458.1" /db_xref="EnsemblGenomes-Gn:BSU35770" /db_xref="EnsemblGenomes-Tr:CAB15594" /db_xref="GOA:P27622" /db_xref="InterPro:IPR011042" /db_xref="SubtiList:BG10453" /db_xref="UniProtKB/Swiss-Prot:P27622" /translation="MRKKELFDFTNITPKLFTELRVADKTVLQSFNFDEKNHQIYTTQ VASGLGKDNTQSYRITRLSLEGLQLDSMLLKHGGHGTNIGIENRNGTIYIWSLYDKPN ETDKSELVCFPYKAGATLDENSKELQRFSNMPFDHRVTPALDMKNRQLAIRQYDTKNN NNKQWVTIFNLDDAIANKNNPLYTINIPDELHYLQGFFLDDGYLYWYTGDTNSKSYPN LITVFDSDNKIVLQKEITVGKDLSTRYENNFREPEGICMYTNPETGAKSLMVGITSGK EGNRISRIYAYHSYENFMNHVPMLRSPLLKTVGHQDTPPERFQPFIQTFILEYNAQNK KWMVPTSGYLPSYTSNLVRNITINADGNLQVTLNERYISLLHQSIEGDFRLKQKDIRM GSWYFAGGEKSNVLEIGFMKGSTKIRPDDAAISNASRMSIFMIVADKIEV*" gene 3549036..3550364 /gene="tagC" /locus_tag="BSU_35770" /old_locus_tag="BSU35770" downshifts 3550359 /Source="Nicolas_upshifts" /id="D1848" /incds=0 /nref=1 /ntot=29 /MaxReadThrough="2.77356" /MaxDrop="4.002" /score="-7.52215775" /energy="-19.3" /TU="NA" /idTUdmin="U2802" /TUdmin=0 /isTUend="TRUE" downshifts complement(3550420) /Source="Nicolas_upshifts" /id="D1849" /incds=0 /nref=141 /ntot=248 /MaxReadThrough="0.94732" /MaxDrop="5.40128" /score="-0.11635468" /energy="-19.3" /TU="NA" /idTUdmin="U2803" /TUdmin="-7" /isTUend="TRUE" CDS complement(3550424..3553066) /gene="lytD" /locus_tag="BSU_35780" /old_locus_tag="BSU35780" /EC_number="3.2.1.96" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:9537764, 10206711, 17298895, 19542270, 22469514" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9537764, 10206711, 17298895, 19542270, 22469514; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="exported N-acetylglucosaminidase (major autolysin) (CWBP90)" /protein_id="NP_391459.1" /db_xref="EnsemblGenomes-Gn:BSU35780" /db_xref="EnsemblGenomes-Tr:CAB15595" /db_xref="GOA:P39848" /db_xref="InterPro:IPR002901" /db_xref="InterPro:IPR003646" /db_xref="InterPro:IPR007730" /db_xref="InterPro:IPR036680" /db_xref="SubtiList:BG10455" /db_xref="UniProtKB/Swiss-Prot:P39848" /translation="MKKRLIAPMLLSAASLAFFAMSGSAQAAAYTDYSLYKVEPSNTF STESQASQAVAKLEKDTGWDASYQASGTTTTYQISASGIHSESEAKAILSGLAKQTSI TGTSSPVGSKQPYVTISSGAISGEKQANTILAKLKQETGVAGAVKAYGAAQPYMNVMT SDIADETKVKALIQSLAKQTGIKSSYQPITHTVSVTTIQSGTIVGDSRAAQIKNAFQK ESGLQASLKETVKGQAYYTFTTAAISGEANAKTLLQQLKQSTGITGSYKSINQKTTVE SYNVQSAYFKGLSTVKDAISQIKKNTGVSGSYQQVGKSTSYTVNMKGITKQQLQKIDT FFKKKKWHYTSSSVKKTTTSAAYQITTAKILGEQQANKAAAFFAQKKVKAAKTAAGST AENQYQLISEETSDQAKVTKGLNILKKNQLSASAKSVKKQIADTFKITTESLLDQTKV NQALTFFKSNHISVASQKTGQTAASSYQITTEAIISQEEIDRVLTFFKQNHIAVTTSK TGQTAYTQYKIVTTQLSSKTALNNGLTYLKSKSVTPSYTTKSNTLYKISVNEQFTGND TAAAASTKLKQLYGWTSSIVKIKNGPQIMKTNYNLSLRDMVQKQMTVSPQTDGAAYVS LTYINTATSTVTADVLNIRSTPEVSPTNVIGQFKKGDKVKVIGQINGWAKINLGWRNA SSDEVVQYVDPNNFSRDSKYYFQFLKLSQTAGLSVTEVNQKVLAGKGILTGRAKAFID AANQYSINELYLISHALLETGNGTSALANGLTYNGKTVYNMYGIGAYDSNPNYYGAKY AYEQGWFTPEAAIIGGAKFIGSSYIHNTAYNQDTLYKMRWSATATHQYATDIGWAYKQ VNRMYSLYSLLDGYTLYFDVPEYR*" gene complement(3550424..3553066) /gene="lytD" /locus_tag="BSU_35780" /old_locus_tag="BSU35780" promotor_-10 complement(3551669..3551688) /Source="Nicolas_upshift_promotors" /id="U2803" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1231 /SigmaFactorBS="gatcaaacgaaagtcaatcagGCACTCACGTttttcaaatcg aATCATATATCAGTAGCAAGCcagaaaaccggtcagacagctgcgagcagctatcaaa t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3551671) /Source="Nicolas_upshifts" /id="U2803" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1231 /SigmaFactorBS="gatcaaacgaaagtcaatcagGCACTCACGTttttcaaatcg aATCATATATCAGTAGCAAGCcagaaaaccggtcagacagctgcgagcagctatcaaa t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(3551701..3551710) /Source="Nicolas_upshift_promotors" /id="U2803" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1231 /SigmaFactorBS="gatcaaacgaaagtcaatcagGCACTCACGTttttcaaatcg aATCATATATCAGTAGCAAGCcagaaaaccggtcagacagctgcgagcagctatcaaa t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(3553101..3553119) /Source="Nicolas_upshift_promotors" /id="U2804" /multdbtbs="SigD" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2808 /SigmaFactorBS="tttattagaaaatggaagtgattcacCTATAAATgaagcatg cgcgtGCCGATAAATAAACTAGTTttatatactcatagaataagaaagaggagaagga a" /listShort="lytD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3553106) /Source="Nicolas_upshifts" /id="U2804" /multdbtbs="SigD" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2808 /SigmaFactorBS="tttattagaaaatggaagtgattcacCTATAAATgaagcatg cgcgtGCCGATAAATAAACTAGTTttatatactcatagaataagaaagaggagaagga a" /listShort="lytD" /GFF_Attribute="listLong" promotor_-35 complement(3553133..3553140) /Source="Nicolas_upshift_promotors" /id="U2804" /multdbtbs="SigD" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2808 /SigmaFactorBS="tttattagaaaatggaagtgattcacCTATAAATgaagcatg cgcgtGCCGATAAATAAACTAGTTttatatactcatagaataagaaagaggagaagga a" /listShort="lytD" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3553195..3554145) /gene="pmiA" /locus_tag="BSU_35790" /old_locus_tag="BSU35790" /EC_number="5.3.1.8" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:7581999, 10704478, 19447949, 27435445" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7581999, 10704478, 19447949, 27435445; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="mannose-6-phosphate isomerase (active on aldose substrates with hydroxyl groups oriented in the same direction at the C-2 and C-3 positions as in mannose)" /protein_id="NP_391460.1" /db_xref="EnsemblGenomes-Gn:BSU35790" /db_xref="EnsemblGenomes-Tr:CAB15596" /db_xref="GOA:P39841" /db_xref="InterPro:IPR001250" /db_xref="InterPro:IPR011051" /db_xref="InterPro:IPR014628" /db_xref="InterPro:IPR014710" /db_xref="PDB:1QWR" /db_xref="SubtiList:BG10454" /db_xref="UniProtKB/Swiss-Prot:P39841" /translation="MTQSPIFLTPVFKEKIWGGTALRDRFGYSIPSESTGECWAISAH PKGPSTVANGPYKGKTLIELWEEHREVFGGVEGDRFPLLTKLLDVKEDTSIKVHPDDY YAGENEEGELGKTECWYIIDCKENAEIIYGHTARSKTELVTMINSGDWEGLLRRIKIK PGDFYYVPSGTLHALCKGALVLETQQNSDATYRVYDYDRLDSNGSPRELHFAKAVNAA TVPHVDGYIDESTESRKGITIKTFVQGEYFSVYKWDINGEAEMAQDESFLICSVIEGS GLLKYEDKTCPLKKGDHFILPAQMPDFTIKGTCTLIVSHI*" gene complement(3553195..3554145) /gene="pmiA" /locus_tag="BSU_35790" /old_locus_tag="BSU35790" downshifts complement(3553207) /Source="Nicolas_upshifts" /id="D1850" /incds=0 /nref=29 /ntot=177 /MaxReadThrough="4.74566" /MaxDrop="3.72936" /score="9.64549533" /energy="-7.7" /TU="U2805" /idTUdmin="U2806" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(3554170..3554188) /Source="Nicolas_upshift_promotors" /id="U2805" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=167 /SigmaFactorBS="cataggaaaaaggcagcttatacgggCGTTTGTaagaggggc gcaccGGGAAAATGATGATCAGTTatttacaggggaggggtacggatcatgacgcaat c" /listShort="yvyI, lytD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3554175) /Source="Nicolas_upshifts" /id="U2805" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=167 /SigmaFactorBS="cataggaaaaaggcagcttatacgggCGTTTGTaagaggggc gcaccGGGAAAATGATGATCAGTTatttacaggggaggggtacggatcatgacgcaat c" /listShort="yvyI, lytD" /GFF_Attribute="listLong" S_feature complement(3554177..3554313) /Source="Nicolas_S_feature" /locus_tag="new_3688579_3688715_c" /HighExp="Lbtran, S0, M40t90, T1.0H, dia0, Mt0, Lbstat, M0t90, Lbexp, T0.30H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.17043900000000001" /TUshortSig="SigA" /TUshortPSig="0.994" /TUlongSig="NA" /TUlongPSig="NA" /label="S1377" promotor_-35 complement(3554203..3554209) /Source="Nicolas_upshift_promotors" /id="U2805" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=167 /SigmaFactorBS="cataggaaaaaggcagcttatacgggCGTTTGTaagaggggc gcaccGGGAAAATGATGATCAGTTatttacaggggaggggtacggatcatgacgcaat c" /listShort="yvyI, lytD" /GFF_Attribute="listLong" /label="promotor_-35" misc_feature complement(3554287..3554306) /Source="Nicolas_upshift_promotors" /id="U2806" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.664335664335664" /psig="0.994005994005994" /xcortree=1553 /SigmaFactorBS="tattaatttgtatcaaaaaaggagaattattcttatcgagga aaaggctgaaacaaagcttcttttcgaCGTGATATAATAGATAGGAAgcgttttcttt g" /listShort="S1377, yvyI" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(3554315) /Source="Nicolas_upshifts" /id="U2806" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.664335664335664" /psig="0.994005994005994" /xcortree=1553 /SigmaFactorBS="tattaatttgtatcaaaaaaggagaattattcttatcgagga aaaggctgaaacaaagcttcttttcgaCGTGATATAATAGATAGGAAgcgttttcttt g" /listShort="S1377, yvyI" /GFF_Attribute="listLong" promotor_-35 3554343..3554349 /Source="Nicolas_upshift_promotors" /id="U2807" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=900 /SigmaFactorBS="cacgtcgaaaagaagctttgtttcagccttttcctcgataAG AATAAttctccttttttgATACAAATTAATaaaaaccgtcaatatgtttaagaaggag a" /listShort="gerBA, gerBB, gerBC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3554363..3554374 /Source="Nicolas_upshift_promotors" /id="U2807" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=900 /SigmaFactorBS="cacgtcgaaaagaagctttgtttcagccttttcctcgataAG AATAAttctccttttttgATACAAATTAATaaaaaccgtcaatatgtttaagaaggag a" /listShort="gerBA, gerBB, gerBC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3554363 /Source="Nicolas_upshifts" /id="U2807" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=900 /SigmaFactorBS="cacgtcgaaaagaagctttgtttcagccttttcctcgataAG AATAAttctccttttttgATACAAATTAATaaaaaccgtcaatatgtttaagaaggag a" /listShort="gerBA, gerBB, gerBC" /GFF_Attribute="listLong" CDS 3554410..3555861 /gene="gerBA" /locus_tag="BSU_35800" /old_locus_tag="BSU35800" /function="16.12: Sense" /experiment="publication(s) with functional evidences, PMID:3110007, 8012571, 10411756, 15774895, 22493018, 23749970, 25681191, 25790435" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 3110007, 8012571, 10411756, 15774895, 22493018, 23749970, 25681191, 25790435; Product type rc: receptor" /codon_start=1 /transl_table=11 /product="component of germinant receptor B" /protein_id="NP_391461.2" /db_xref="EnsemblGenomes-Gn:BSU35800" /db_xref="EnsemblGenomes-Tr:CAB15597" /db_xref="GOA:P39569" /db_xref="InterPro:IPR004995" /db_xref="SubtiList:BG10640" /db_xref="UniProtKB/Swiss-Prot:P39569" /translation="MQIDSDLQNNLDTLKKTLGQNDDMMFYTFAFGDSRQKACLLYID GLTENKMLAQYVISPLQKEALAHKECSIEDLSAFFFGFHHSVVSTMKEIEQLVFSGQA ILLADGYRGGLAFDTKSVATRSLDEPSSEVVERGPKIGFIEKLRTNTALLRERTSDPN LVIKEMTLGKRTKKKIAVAYIQDIAPDYVVKEVFKRLKSVNIDNLPESGTLEQLIEDE PFSIFPTILSTERPDRVESSLLEGRVSILVDGTPFALIVPATVDEFIHSPDDYSQRWI PMSLVRLLRYSSILITIYLPGLYISLVSFHTGLLPTRMAISIAGSRLNVPFPPFVEAF IMIFTIELIREAGLRLPKPIGQTIGLIGGVVIGQAAVQAQIVSALMVIVVSVTALASF TVPSYAYNFPLRIIRIGVMISATALGMYGVIMVYLFVIGHLMRLKSFGQDYIIPIMAQ PGQDLKDTVIRIPTMFLKRRPTRNDPEDNIRQR*" gene 3554410..3555861 /gene="gerBA" /locus_tag="BSU_35800" /old_locus_tag="BSU35800" CDS 3555867..3556973 /gene="gerBB" /locus_tag="BSU_35810" /old_locus_tag="BSU35810" /function="16.12: Sense" /experiment="publication(s) with functional evidences, PMID:15774895, 15849754, 16352818, 16850406, 22493018" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15774895, 15849754, 16352818, 16850406, 22493018; Product type rc: receptor" /codon_start=1 /transl_table=11 /product="component of germinant receptor B" /protein_id="NP_391462.2" /db_xref="EnsemblGenomes-Gn:BSU35810" /db_xref="EnsemblGenomes-Tr:CAB15598" /db_xref="GOA:P39570" /db_xref="InterPro:IPR002293" /db_xref="InterPro:IPR004761" /db_xref="SubtiList:BG10641" /db_xref="UniProtKB/Swiss-Prot:P39570" /translation="MRKSEHKLTFMQTLIMISSTLIGAGVLTLPRSAAETGSPSGWLM ILLQGVIFIIIVLLFLPFLQKNSGKTLFKLNSIVAGKFIGFLLNLYICLYFIGIVCFQ ARILGEVVGFFLLKNTPMAVVVFIFLAVAIYHVGGGVYSIAKVYAYIFPITLIIFMML LMFSFRLFQLDFIRPVFEGGYQSFFSLFPKTLLYFSGFEIIFYLVPFMRDPKQVKKAV ALGIATSTLFYSITLLIVIGCMTVAEAKTVTWPTISLIHALEVPGIFIERFDLFLQLT WTAQQFACMLGSFKGAHIGLTEIFHLKNKNNAWLLTAMLAATFFITMYPKDLNDVFYY GTLLGYAFLIVITIPFFVWFLSWIQKKIGRGQLQ*" gene 3555867..3556973 /gene="gerBB" /locus_tag="BSU_35810" /old_locus_tag="BSU35810" CDS 3556970..3558094 /gene="gerBC" /locus_tag="BSU_35820" /old_locus_tag="BSU35820" /function="16.12: Sense" /experiment="publication(s) with functional evidences, PMID:15774895, 15849754, 16352818, 16850406, 20654628, 21685283, 22493018" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15774895, 15849754, 16352818, 16850406, 20654628, 21685283, 22493018; Product type lp: lipoprotein" /codon_start=1 /transl_table=11 /product="lipoprotein component of the germination receptor B" /protein_id="NP_391463.1" /db_xref="EnsemblGenomes-Gn:BSU35820" /db_xref="EnsemblGenomes-Tr:CAB15599" /db_xref="GOA:P39571" /db_xref="InterPro:IPR008844" /db_xref="PDB:3N54" /db_xref="SubtiList:BG10642" /db_xref="UniProtKB/Swiss-Prot:P39571" /translation="MKTASKFSVMFFMLLALCGCWDVKDIEQLSFARGLAIDETNDHQ YKLTYQNLLPQSEDSQASGKPEFVNVTSHGKTILEAVSDVSIKDPPVYSDHLKVILLG EKLMRNQNVDQVLNHFIRDDELRRSSYLMAARGNAADVFTKGNPNQQQPMPSEKLIDL TTHSGYNGKIMIPLRIGRASVYSQNGYSYLIQAVKNEKGKAKYDGAGIIKRGSNKLVG FLSADETQTLSWVMGTIQGGVMPTTDKGHPITFEIKKSKTKIKPVIENGKPVFHISVK TKGILTEDQNPNENSFSKSYLHRLENIFEKKLERDVKQVMDKLQHEYKTDPVFLSDHI RIQHPDYWNKVKGHWDEIFSETDFKYDISFKIINFGTVGK*" gene 3556970..3558094 /gene="gerBC" /locus_tag="BSU_35820" /old_locus_tag="BSU35820" S_feature complement(3557197..3558091) /Source="Nicolas_S_feature" /locus_tag="new_3691599_3692493_c" /HighExp="Etha, Sw, Salt, Heat, S8, B36, Gly, S7, LPhT, S6" /AntisenseName="gerBC" /AntisenseCor="0.12062795031199899" /AntisenseRegPval="-1.3" /CDS_PredictionProba="NA" /TUshortSig="SigB" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1378" downshifts 3558084 /Source="Nicolas_upshifts" /id="D1851" /incds=0 /nref=18 /ntot=72 /MaxReadThrough="0.37711" /MaxDrop="4.85405" /score="35.6875936" /energy="-14.9" /TU="NA" /idTUdmin="U2807" /TUdmin=0 /isTUend="TRUE" CDS complement(3558131..3559504) /gene="ywtG" /locus_tag="BSU_35830" /old_locus_tag="BSU35830" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative carbohydrate/proton transporter" /protein_id="NP_391464.2" /db_xref="EnsemblGenomes-Gn:BSU35830" /db_xref="EnsemblGenomes-Tr:CAB15600" /db_xref="GOA:C0SPB2" /db_xref="InterPro:IPR003663" /db_xref="InterPro:IPR005828" /db_xref="InterPro:IPR005829" /db_xref="InterPro:IPR020846" /db_xref="InterPro:IPR036259" /db_xref="SubtiList:BG12538" /db_xref="UniProtKB/Swiss-Prot:C0SPB2" /translation="MKKQSNIWLYFFGALGGALYGYDTGVISGAILFMKKELGLNAFT EGLVVSSLLVGAILGSGAAGKLTDRFGRKKAIMAAALLFCIGGLGVALAPNTGVMVLF RIILGLAVGTSTTIVPLYLSELAPKHKRGALSSLNQLMITVGILLSYIVNYIFADAEA WRWMLGLAAVPSLLLLIGILFMPESPRWLFTNGEESKAKKILEKLRGTKDIDQEIHDI KEAEKQDEGGLKELFDPWVRPALIAGLGLAFLQQFIGTNTIIYYAPKTFTNVGFGNSA SILGTVGIGTVNVLMTLVAIKIIDKIGRKPLLLFGNAGMVISLIVLALVNLFFDNTPA ASWTTVICLGVFIVVFAVSWGPVVWVMLPELFPLHVRGIGTGVSTLMLHVGTLIVSLT YPILMEAIGISYLFLIYAAIGIMAFLFVRFKVTETKGRSLEEIEQDLRDKNGQGGAAG KQQTVGT*" gene complement(3558131..3559504) /gene="ywtG" /locus_tag="BSU_35830" /old_locus_tag="BSU35830" downshifts complement(3558136) /Source="Nicolas_upshifts" /id="D1852" /incds=0 /nref=13 /ntot=90 /MaxReadThrough="6.08746" /MaxDrop="3.99424" /score="22.7548183" /energy="-16.7" /TU="U2808" /idTUdmin="U2808" /TUdmin="-900" /isTUend="FALSE" S_feature complement(3559505..3559568) /Source="Nicolas_S_feature" /locus_tag="new_3693907_3693970_c" /HighExp="Etha, Salt, Gly, Heat, Sw, LPhT, HiTm, Diami, B60, UNK1" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigB" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1379" promotor_-10 complement(3559556..3559574) /Source="Nicolas_upshift_promotors" /id="U2808" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=188 /SigmaFactorBS="atgattggaaaacttatgatcagaaaaataaaaaGGTTTAAt ggccggaaaaagaGGCTAAAAGATTTCTAAAAaaatcccacagacaatgtcattgcag c" /listShort="S1379, ywtG, S1378" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3559569) /Source="Nicolas_upshifts" /id="U2808" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=188 /SigmaFactorBS="atgattggaaaacttatgatcagaaaaataaaaaGGTTTAAt ggccggaaaaagaGGCTAAAAGATTTCTAAAAaaatcccacagacaatgtcattgcag c" /listShort="S1379, ywtG, S1378" /GFF_Attribute="listLong" promotor_-35 complement(3559589..3559595) /Source="Nicolas_upshift_promotors" /id="U2808" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=188 /SigmaFactorBS="atgattggaaaacttatgatcagaaaaataaaaaGGTTTAAt ggccggaaaaagaGGCTAAAAGATTTCTAAAAaaatcccacagacaatgtcattgcag c" /listShort="S1379, ywtG, S1378" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 3559655..3559664 /Source="Nicolas_upshift_promotors" /id="U2809" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1659 /SigmaFactorBS="ttttccaatcatttacttgtatttttttcaatgtcgcCGAAA CATTTtacctgctgcgGCGTCCAATATAAGGTgattcagtacattatcgttatcaatt t" /listShort="S1380, ywtF, S1381, ywtE" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3559676..3559691 /Source="Nicolas_upshift_promotors" /id="U2809" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1659 /SigmaFactorBS="ttttccaatcatttacttgtatttttttcaatgtcgcCGAAA CATTTtacctgctgcgGCGTCCAATATAAGGTgattcagtacattatcgttatcaatt t" /listShort="S1380, ywtF, S1381, ywtE" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 3559678..3559798 /Source="Nicolas_S_feature" /locus_tag="new_3694080_3694200" /HighExp="T-0.40H, LBGstat, T-1.10H, T0.30H, Heat, T-1.40H, T1.30H, T1.0H, T0.0H, Paraq" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigWXY" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1380" upshifts 3559678 /Source="Nicolas_upshifts" /id="U2809" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1659 /SigmaFactorBS="ttttccaatcatttacttgtatttttttcaatgtcgcCGAAA CATTTtacctgctgcgGCGTCCAATATAAGGTgattcagtacattatcgttatcaatt t" /listShort="S1380, ywtF, S1381, ywtE" /GFF_Attribute="listLong" promotor_-35 3559773..3559780 /Source="Nicolas_upshift_promotors" /id="U2810" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.58041958041958" /psig="0.997002997002997" /xcortree=2249 /SigmaFactorBS="tataggaatatttatcgaaaaatgtctttcgagTAGTTGCCc catggcaaatagAATGGTACGCTTCAAATATTaaagaaacgtgaggtattgatatatg g" /listShort="ywtF, S1381, ywtE" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3559794..3559813 /Source="Nicolas_upshift_promotors" /id="U2810" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.58041958041958" /psig="0.997002997002997" /xcortree=2249 /SigmaFactorBS="tataggaatatttatcgaaaaatgtctttcgagTAGTTGCCc catggcaaatagAATGGTACGCTTCAAATATTaaagaaacgtgaggtattgatatatg g" /listShort="ywtF, S1381, ywtE" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3559800 /Source="Nicolas_upshifts" /id="U2810" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.58041958041958" /psig="0.997002997002997" /xcortree=2249 /SigmaFactorBS="tataggaatatttatcgaaaaatgtctttcgagTAGTTGCCc catggcaaatagAATGGTACGCTTCAAATATTaaagaaacgtgaggtattgatatatg g" /listShort="ywtF, S1381, ywtE" /GFF_Attribute="listLong" CDS 3559837..3560805 /gene="tagT" /locus_tag="BSU_35840" /old_locus_tag="BSU35840" /function="12: Regulatory functions" /experiment="publication(s) with functional evidences, PMID:19099556, 22432711, 29107701" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 19099556, 22432711, 29107701; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="teichoic acid-peptidoglycan tethering enzyme (LCP component) with transcription regulator domain of capsule synthesis" /protein_id="NP_391465.2" /db_xref="EnsemblGenomes-Gn:BSU35840" /db_xref="EnsemblGenomes-Tr:CAB15601" /db_xref="GOA:Q7WY78" /db_xref="InterPro:IPR004474" /db_xref="PDB:3MEJ" /db_xref="PDB:4DE9" /db_xref="SubtiList:BG12537" /db_xref="UniProtKB/Swiss-Prot:Q7WY78" /translation="MEERSQRRKKKRKLKKWVKVVAGLMAFLVIAAGSVGAYAFVKLN NASKEAHVSLARGEQSVKRIKEFDPGKDSFSVLLLGIDAREKNGETVDQARSDANVLV TFNRKEKTAKMLSIPRDAYVNIPGHGYDKFTHAHAYGGVDLTVKTVEEMLDIPVDYVV ESNFTAFEDVVNELNGVKVTVKSDKVIQQIKKDTKGKVVLQKGTHTLDGEEALAYVRT RKADSDLLRGQRQMEVLSAIIDKSKSLSSIPAYDDIVDTMGQNLKMNLSLKDAIGLFP FITSLKSVESIQLTGYDYEPAGVYYFKLNQQKLQEVKKELQNDLGV*" gene 3559837..3560805 /gene="tagT" /locus_tag="BSU_35840" /old_locus_tag="BSU35840" downshifts 3560790 /Source="Nicolas_upshifts" /id="D1853" /incds=0 /nref=27 /ntot=139 /MaxReadThrough="6.07699" /MaxDrop="4.78541" /score="17.3040761" /energy="-17.8" /TU="U2809,U2810" /idTUdmin="U2809" /TUdmin="-1012" /isTUend="FALSE" promotor_-35 3560849..3560856 /Source="Nicolas_upshift_promotors" /id="U2811" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.667332667332667" /psig="0.982017982017982" /xcortree=1778 /SigmaFactorBS="cgattacgccatcccgttttacatatttcctTGTTGAAAatt atcaaagtaacGTTTAGCCTTAATTTATATGgattatgtttcacaggcaagctgaaca t" /listShort="S1381, ywtE" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3560871..3560890 /Source="Nicolas_upshift_promotors" /id="U2811" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.667332667332667" /psig="0.982017982017982" /xcortree=1778 /SigmaFactorBS="cgattacgccatcccgttttacatatttcctTGTTGAAAatt atcaaagtaacGTTTAGCCTTAATTTATATGgattatgtttcacaggcaagctgaaca t" /listShort="S1381, ywtE" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 3560878..3560960 /Source="Nicolas_S_feature" /locus_tag="new_3695280_3695362" /HighExp="Etha, dia5, Lbtran, dia15, LBGexp, LBGtran, G150, Mt0, G180, H2O2" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA, SigWXY" /TUshortPSig="0.982, 0.997, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S1381" upshifts 3560878 /Source="Nicolas_upshifts" /id="U2811" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.667332667332667" /psig="0.982017982017982" /xcortree=1778 /SigmaFactorBS="cgattacgccatcccgttttacatatttcctTGTTGAAAatt atcaaagtaacGTTTAGCCTTAATTTATATGgattatgtttcacaggcaagctgaaca t" /listShort="S1381, ywtE" /GFF_Attribute="listLong" CDS 3560961..3561821 /gene="ribZB" /locus_tag="BSU_35850" /old_locus_tag="BSU35850" /EC_number="3.1.3.-" /function="4.9: Riboflavin, FMN, and FAD" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1b: Function from experimental evidences in the studied species; PubMedId: 26316208; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="5-amino-6-ribitylamino-2,4(1H, 3H)-pyrimidinedione 5'-phosphate phosphatase (promiscuous activity)" /protein_id="NP_391466.1" /db_xref="EnsemblGenomes-Gn:BSU35850" /db_xref="EnsemblGenomes-Tr:CAB15602" /db_xref="GOA:P96741" /db_xref="InterPro:IPR000150" /db_xref="InterPro:IPR006379" /db_xref="InterPro:IPR023214" /db_xref="InterPro:IPR036412" /db_xref="SubtiList:BG12536" /db_xref="UniProtKB/Swiss-Prot:P96741" /translation="MKCIAIDLDGTLLNKESVISAENREAIKRAVDAGILVTICTGRA TFDVKALLDDLDIPIIAANGGTIHDTGYRLISRTLMDQEAGKAIADYLLSKNIYFEVY TDDHLLSPFDGEAKLHAELDILKSANPNEQTDDLWQGAMTQFKQFGIKPIPHIESVFD GGENIYKLLCFSFDMDKLKQAKEELKHHKKLAQTSSGKHIIEILPASSGKGRALTKLA DIYGIETQDIYAIGDSPNDLSMFEVAGHRIAMENAIDELKEKSTFVTKSNDENGVAYF IDQLLSGQYA*" gene 3560961..3561821 /gene="ribZB" /locus_tag="BSU_35850" /old_locus_tag="BSU35850" downshifts 3561802 /Source="Nicolas_upshifts" /id="D1854" /incds=0 /nref=163 /ntot=235 /MaxReadThrough="3.35965" /MaxDrop="5.65658" /score="24.125299" /energy="-9.8" /TU="NA" /idTUdmin="U2809" /TUdmin=0 /isTUend="TRUE" CDS complement(3561855..3563096) /gene="pgdS" /locus_tag="BSU_35860" /old_locus_tag="BSU35860" /EC_number="3.4.19.-" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:12073126, 12644511, 16689787, 16952838, 26158264, 28664519" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12073126, 12644511, 16689787, 16952838, 26158264, 28664519; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="gamma-DD-glutamyl hydrolase (PGA depolymerase)" /protein_id="NP_391467.1" /db_xref="EnsemblGenomes-Gn:BSU35860" /db_xref="EnsemblGenomes-Tr:CAB15603" /db_xref="GOA:P96740" /db_xref="InterPro:IPR000064" /db_xref="SubtiList:BG12535" /db_xref="UniProtKB/Swiss-Prot:P96740" /translation="MNTLANWKKFLLVAVIICFLVPIMTKAEIAEADTSSELIVSEAK NLLGYQYKYGGETPKEGFDPSGLIQYVFSKADIHLPRSVNDQYKIGTAVKPENLKPGD ILFFKKEGSTGTVPTHDALYIGDGQMVHSTQSKGVIITNYKKSSYWSGTYIGARRIAA DPATADVPVVQEAEKYIGVPYVFGGSTPSEGFDCSGLVQYVFQQALGIYLPRSAEQQW AVGEKVAPQNIKPGDVVYFSNTYKTGISHAGIYAGAGRFIQASRSEKVTISYLSEDYW KSKMTGIRRFDNLTIPKENPIVSEATLYVGEVPYKQGGVTPETGFDTAGFVQYVYQKA AGISLPRYATSQYNAGTKIEKADLKPGDIVFFQSTSLNPSIYIGNGQVVHVTLSNGVT ITNMNTSTYWKDKYAGSIRVQ*" gene complement(3561855..3563096) /gene="pgdS" /locus_tag="BSU_35860" /old_locus_tag="BSU35860" downshifts complement(3561874) /Source="Nicolas_upshifts" /id="D1855" /incds=0 /nref=228 /ntot=317 /MaxReadThrough="2.27329" /MaxDrop="7.15996" /score="10.2499259" /energy="-9.8" /TU="NA" /idTUdmin="U2812" /TUdmin="-18" /isTUend="TRUE" promotor_-10 complement(3563118..3563136) /Source="Nicolas_upshift_promotors" /id="U2812" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=2804 /SigmaFactorBS="ttatttgcccagcatattcattctgtaaaaatattaaaaagt ctCTTAACATattcaaaaaaatACCGATGTTAAAACTGCAAaaagaggaggagataat a" /listShort="pgdS" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3563140) /Source="Nicolas_upshifts" /id="U2812" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=2804 /SigmaFactorBS="ttatttgcccagcatattcattctgtaaaaatattaaaaagt ctCTTAACATattcaaaaaaatACCGATGTTAAAACTGCAAaaagaggaggagataat a" /listShort="pgdS" /GFF_Attribute="listLong" promotor_-35 complement(3563149..3563156) /Source="Nicolas_upshift_promotors" /id="U2812" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=2804 /SigmaFactorBS="ttatttgcccagcatattcattctgtaaaaatattaaaaagt ctCTTAACATattcaaaaaaatACCGATGTTAAAACTGCAAaaagaggaggagataat a" /listShort="pgdS" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3563237..3563404) /gene="edmS" /locus_tag="BSU_35870" /old_locus_tag="BSU35870" /function="16.13: Shape" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:16267300, 16689787, 20812257, 21357437, 23583563, 25843804" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16267300, 16689787, 20812257, 21357437, 23583563, 25843804; Product type f : factor" /codon_start=1 /transl_table=11 /product="factor required extrachromosomal elements maintenance" /protein_id="NP_391468.1" /db_xref="EnsemblGenomes-Gn:BSU35870" /db_xref="EnsemblGenomes-Tr:CAB15604" /db_xref="SubtiList:BG12534" /db_xref="UniProtKB/Swiss-Prot:P96739" /translation="MKFVKAIWPFVAVAIVFMFMSAFKFNDQLTDQEKQKIDMEMNKI QQQEEPVNANK*" gene complement(3563237..3563404) /gene="edmS" /locus_tag="BSU_35870" /old_locus_tag="BSU35870" downshifts complement(3563264) /Source="Nicolas_upshifts" /id="D1856" /incds=0 /nref=1 /ntot=47 /MaxReadThrough="0.6752" /MaxDrop="2.78178" /score="24.9141523" /energy="-14.7" /TU="NA" /idTUdmin="U2812" /TUdmin="-1408" /isTUend="FALSE" CDS complement(3563419..3564561) /gene="capA" /locus_tag="BSU_35880" /old_locus_tag="BSU35880" /EC_number="6.3.2.-" /function="16.8: Protect" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:11606194, 11751809, 12644511, 16689787, 19745567, 27818647" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11606194, 11751809, 12644511, 16689787, 19745567, 27818647; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="capsular polyglutamate synthetase (acid resistance)" /protein_id="NP_391469.1" /db_xref="EnsemblGenomes-Gn:BSU35880" /db_xref="EnsemblGenomes-Tr:CAB15605" /db_xref="InterPro:IPR019079" /db_xref="InterPro:IPR029052" /db_xref="SubtiList:BG12533" /db_xref="UniProtKB/Swiss-Prot:P96738" /translation="MKKELSFHEKLLKLTKQQKKKTNKHVFIAIPIVFVLMFAFMWAG KAETPKVKTYSDDVLSASFVGDIMMGRYVEKVTEQKGADSIFQYVEPIFRASDYVAGN FENPVTYQKNYKQADKEIHLQTNKESVKVLKDMNFTVLNSANNHAMDYGVQGMKDTLG EFAKQNLDIVGAGYSLSDAKKKISYQKVNGVTIATLGFTDVSGKGFAAKKNTPGVLPA DPEIFIPMISEAKKHADIVVVQSHWGQEYDNDPNDRQRQLARAMSDAGADIIVGHHPH VLEPIEVYNGTVIFYSLGNFVFDQGWTRTRDSALVQYHLKKNGTGRFEVTPIDIHEAT PAPVKKDSLKQKTIIRELTKDSNFAWKVEDGKLTFDIDHSDKLKSK*" gene complement(3563419..3564561) /gene="capA" /locus_tag="BSU_35880" /old_locus_tag="BSU35880" CDS complement(3564580..3565029) /gene="capC" /locus_tag="BSU_35890" /old_locus_tag="BSU35890" /EC_number="6.3.2.-" /function="16.13: Shape" /function="16.1: Circulate" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:11606194, 11751809, 15849754, 16689787, 16850406, 19734658" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11606194, 11751809, 15849754, 16689787, 16850406, 19734658; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="capsular polyglutamate amide ligase/translocase subunit" /protein_id="NP_391470.1" /db_xref="EnsemblGenomes-Gn:BSU35890" /db_xref="EnsemblGenomes-Tr:CAB15606" /db_xref="GOA:P96737" /db_xref="InterPro:IPR008338" /db_xref="SubtiList:BG12532" /db_xref="UniProtKB/Swiss-Prot:P96737" /translation="MFGSDLYIALILGVLLSLIFAEKTGIVPAGLVVPGYLGLVFNQP VFILLVLLVSLLTYVIVKYGLSKFMILYGRRKFAAMLITGIVLKIAFDFLYPIVPFEI AEFRGIGIIVPGLIANTIQKQGLTITFGSTLLLSGATFAIMFVYYLI*" gene complement(3564580..3565029) /gene="capC" /locus_tag="BSU_35890" /old_locus_tag="BSU35890" promotor_-35 3564723..3564729 /Source="Nicolas_upshift_promotors" /id="U2813" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.853146853146853" /psig="0.853146853146853" /xcortree=131 /SigmaFactorBS="ttggcaattaaacctggcacgatgatgccgattcctcgaaat tctgCGATTTCaaatggtacaatcGGGTATAGAAAATCAAACGcgatttttaggacga t" /listShort="S1382" /listLong="rbsR, rbsK, rbsD, rbsA, rbsC, rbsB, ywsB" /label="promotor_-35" upshifts 3564737 /Source="Nicolas_upshifts" /id="U2813" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.853146853146853" /psig="0.853146853146853" /xcortree=131 /SigmaFactorBS="ttggcaattaaacctggcacgatgatgccgattcctcgaaat tctgCGATTTCaaatggtacaatcGGGTATAGAAAATCAAACGcgatttttaggacga t" /listShort="S1382" /listLong="rbsR, rbsK, rbsD, rbsA, rbsC, rbsB, ywsB" promotor_-10 3564743..3564761 /Source="Nicolas_upshift_promotors" /id="U2813" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.853146853146853" /psig="0.853146853146853" /xcortree=131 /SigmaFactorBS="ttggcaattaaacctggcacgatgatgccgattcctcgaaat tctgCGATTTCaaatggtacaatcGGGTATAGAAAATCAAACGcgatttttaggacga t" /listShort="S1382" /listLong="rbsR, rbsK, rbsD, rbsA, rbsC, rbsB, ywsB" /label="promotor_-10" S_feature 3564750..3566959 /Source="Nicolas_S_feature" /locus_tag="new_3699152_3701361" /HighExp="Sw, Salt, dia5, BC, B60, Diami, Lbstat, H2O2, dia15, Gly" /AntisenseName="pgsB" /AntisenseCor="7.6745622610153399E-2" /AntisenseRegPval="-0.7" /CDS_PredictionProba="0.40410200000000002" /TUshortSig="SigB" /TUshortPSig="0.853" /TUlongSig="NA" /TUlongPSig="NA" /label="S1382" CDS complement(3565044..3566225) /gene="capB" /locus_tag="BSU_35900" /old_locus_tag="BSU35900" /EC_number="6.3.2.-" /function="16.13: Shape" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 11606194, 11751809, 12644511, 16689787, 19420703, 19734658, 27446033; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="capsular polyglutamate synthetase (ATP-dependentamide ligase)" /protein_id="NP_391471.2" /db_xref="EnsemblGenomes-Gn:BSU35900" /db_xref="EnsemblGenomes-Tr:CAB15607" /db_xref="GOA:P96736" /db_xref="InterPro:IPR008337" /db_xref="InterPro:IPR013221" /db_xref="InterPro:IPR036565" /db_xref="SubtiList:BG12531" /db_xref="UniProtKB/Swiss-Prot:P96736" /translation="MWLLIIACAVILVIGILEKRRHQKNIDALPVRVNINGIRGKSTV TRLTTGILIEAGYKTVGKTTGTDARMIYWDTPEEKPIKRKPQGPNIGEQKEVMRETVE RGANAIVSECMAVNPDYQIIFQEELLQANIGVIVNVLEDHMDVMGPTLDEIAEAFTAT IPYNGHLVITDSEYTEFFKQKAKERNTKVIIADNSKITDEYLRKFEYMVFPDNASLAL GVAQALGIDEETAFKGMLNAPPDPGAMRILPLISPSEPGHFVNGFAANDASSTLNIWK RVKEIGYPTDDPIIIMNCRADRVDRTQQFANDVLPYIEASELILIGETTEPIVKAYEE GKIPADKLHDLEYKSTDEIMELLKKRMHNRVIYGVGNIHGAAEPLIEKIHEYKVKQLV S*" gene complement(3565044..3566225) /gene="capB" /locus_tag="BSU_35900" /old_locus_tag="BSU35900" promotor_-35 3566939..3566946 /Source="Nicolas_upshift_promotors" /id="U2814" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.911088911088911" /psig=1 /xcortree=326 /SigmaFactorBS="atatatacaatttacaattagatttcttttgatattttTATT GCTAacttcggattgttcaTGATAATCTATCTATGTAAAcggttacataaacaaggag g" /listShort="rbsR, rbsK, rbsD, rbsA, rbsC, rbsB, ywsB" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 3566961 /Source="Nicolas_upshifts" /id="U2814" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.911088911088911" /psig=1 /xcortree=326 /SigmaFactorBS="atatatacaatttacaattagatttcttttgatattttTATT GCTAacttcggattgttcaTGATAATCTATCTATGTAAAcggttacataaacaaggag g" /listShort="rbsR, rbsK, rbsD, rbsA, rbsC, rbsB, ywsB" /GFF_Attribute="listLong" promotor_-10 3566962..3566981 /Source="Nicolas_upshift_promotors" /id="U2814" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.911088911088911" /psig=1 /xcortree=326 /SigmaFactorBS="atatatacaatttacaattagatttcttttgatattttTATT GCTAacttcggattgttcaTGATAATCTATCTATGTAAAcggttacataaacaaggag g" /listShort="rbsR, rbsK, rbsD, rbsA, rbsC, rbsB, ywsB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3566982) /Source="Nicolas_upshifts" /id="U2815" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.999000999001" /psig="0.000999000999001" /xcortree=694 /SigmaFactorBS="ccgccgctccggcgacatctttaattgtaGCCAAaacagctC CTCCTTGTTTATGTaaccgtttacatagatagattatcatgaacaatccgaagttagc a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 complement(3566987..3567001) /Source="Nicolas_upshift_promotors" /id="U2815" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.999000999001" /psig="0.000999000999001" /xcortree=694 /SigmaFactorBS="ccgccgctccggcgacatctttaattgtaGCCAAaacagctC CTCCTTGTTTATGTaaccgtttacatagatagattatcatgaacaatccgaagttagc a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 complement(3567009..3567013) /Source="Nicolas_upshift_promotors" /id="U2815" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.999000999001" /psig="0.000999000999001" /xcortree=694 /SigmaFactorBS="ccgccgctccggcgacatctttaattgtaGCCAAaacagctC CTCCTTGTTTATGTaaccgtttacatagatagattatcatgaacaatccgaagttagc a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" CDS 3567009..3567989 /gene="rbsR" /locus_tag="BSU_35910" /old_locus_tag="BSU35910" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:11750820, 16519689" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11750820, 16519689; Product type r: regulator" /codon_start=1 /transl_table=11 /product="ribose operon repressor (LacI family, D-ribose)" /protein_id="NP_391472.1" /db_xref="EnsemblGenomes-Gn:BSU35910" /db_xref="EnsemblGenomes-Tr:CAB15608" /db_xref="GOA:P36944" /db_xref="InterPro:IPR000843" /db_xref="InterPro:IPR010982" /db_xref="InterPro:IPR028082" /db_xref="SubtiList:BG10876" /db_xref="UniProtKB/Swiss-Prot:P36944" /translation="MATIKDVAGAAGVSVATVSRNLNDNGYVHEETRTRVIAAMAKLN YYPNEVARSLYKRESRLIGLLLPDITNPFFPQLARGAEDELNREGYRLIFGNSDEELK KELEYLQTFKQNHVAGIIAATNYPDLEEYSGMNYPVVFLDRTLEGAPSVSSDGYTGVK LAAQAIIHGKSQRITLLRGPAHLPTAQDRFNGALEILKQAEVDFQVIETASFSIKDAQ SMAKELFASYPATDGVIASNDIQAAAVLHEALRRGKNVPEDIQIIGYDDIPQSGLLFP PLSTIKQPAYDMGKEAAKLLLGIIKKQPLAETAIQMPVTYIGRKTTRKED*" gene 3567009..3567989 /gene="rbsR" /locus_tag="BSU_35910" /old_locus_tag="BSU35910" promotor_-35 3567838..3567845 /Source="Nicolas_upshift_promotors" /id="U2816" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.532467532467532" /psig="0.759240759240759" /xcortree=1571 /SigmaFactorBS="cgcaaagcggacttctgttcccgcCACTTTCTacaattaaac agcCCGCATATGATATGGGGAAAgaagctgccaaactgcttttgggtatcattaaaaa a" /listShort="rbsK, rbsD, rbsA, rbsC, rbsB, ywsB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3567859..3567878 /Source="Nicolas_upshift_promotors" /id="U2816" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.532467532467532" /psig="0.759240759240759" /xcortree=1571 /SigmaFactorBS="cgcaaagcggacttctgttcccgcCACTTTCTacaattaaac agcCCGCATATGATATGGGGAAAgaagctgccaaactgcttttgggtatcattaaaaa a" /listShort="rbsK, rbsD, rbsA, rbsC, rbsB, ywsB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3567874 /Source="Nicolas_upshifts" /id="U2816" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.532467532467532" /psig="0.759240759240759" /xcortree=1571 /SigmaFactorBS="cgcaaagcggacttctgttcccgcCACTTTCTacaattaaac agcCCGCATATGATATGGGGAAAgaagctgccaaactgcttttgggtatcattaaaaa a" /listShort="rbsK, rbsD, rbsA, rbsC, rbsB, ywsB" /GFF_Attribute="listLong" CDS 3567991..3568872 /gene="rbsK" /locus_tag="BSU_35920" /old_locus_tag="BSU35920" /EC_number="2.7.1.15" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 7921236, 16978644; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="ribokinase" /protein_id="NP_391473.1" /db_xref="EnsemblGenomes-Gn:BSU35920" /db_xref="EnsemblGenomes-Tr:CAB15609" /db_xref="GOA:P36945" /db_xref="InterPro:IPR002139" /db_xref="InterPro:IPR002173" /db_xref="InterPro:IPR011611" /db_xref="InterPro:IPR011877" /db_xref="InterPro:IPR029056" /db_xref="SubtiList:BG10877" /db_xref="UniProtKB/Swiss-Prot:P36945" /translation="MRNICVIGSCSMDLVVTSDKRPKAGETVLGTSFQTVPGGKGANQ AVAAARLGAQVFMVGKVGDDHYGTAILNNLKANGVRTDYMEPVTHTESGTAHIVLAEG DNSIVVVKGANDDITPAYALNALEQIEKVDMVLIQQEIPEETVDEVCKYCHSHDIPII LNPAPARPLKQETIDHATYLTPNEHEASILFPELTISEALALYPAKLFITEGKQGVRY SAGSKEVLIPSFPVEPVDTTGAGDTFNAAFAVALAEGKDIEAALRFANRAASLSVCSF GAQGGMPTRNEVEELLS*" gene 3567991..3568872 /gene="rbsK" /locus_tag="BSU_35920" /old_locus_tag="BSU35920" CDS 3568869..3569264 /gene="rbsD" /locus_tag="BSU_35930" /old_locus_tag="BSU35930" /EC_number="5.4.99.62" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 7921236, 12738765, 21276853; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="D-ribose pyranase" /protein_id="NP_391474.1" /db_xref="EnsemblGenomes-Gn:BSU35930" /db_xref="EnsemblGenomes-Tr:CAB15610" /db_xref="GOA:P36946" /db_xref="InterPro:IPR007721" /db_xref="InterPro:IPR023064" /db_xref="InterPro:IPR023750" /db_xref="PDB:1OGC" /db_xref="PDB:1OGD" /db_xref="PDB:1OGE" /db_xref="PDB:1OGF" /db_xref="SubtiList:BG10878" /db_xref="UniProtKB/Swiss-Prot:P36946" /translation="MKKHGILNSHLAKILADLGHTDKIVIADAGLPVPDGVLKIDLSL KPGLPAFQDTAAVLAEEMAVEKVIAAAEIKASNQENAKFLENLFSEQEIEYLSHEEFK LLTKDAKAVIRTGEFTPYANCILQAGVLF*" gene 3568869..3569264 /gene="rbsD" /locus_tag="BSU_35930" /old_locus_tag="BSU35930" CDS 3569280..3570761 /gene="rbsA" /locus_tag="BSU_35940" /old_locus_tag="BSU35940" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:7921236" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7921236; Product type t : transporter" /codon_start=1 /transl_table=11 /product="ribose ABC transporter (ATP-binding protein)" /protein_id="NP_391475.1" /db_xref="EnsemblGenomes-Gn:BSU35940" /db_xref="EnsemblGenomes-Tr:CAB15611" /db_xref="GOA:P36947" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR015861" /db_xref="InterPro:IPR017871" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG10879" /db_xref="UniProtKB/Swiss-Prot:P36947" /translation="MQIEMKDIHKTFGKNQVLSGVSFQLMPGEVHALMGENGAGKSTL MNILTGLHKADKGQISINGNETYFSNPKEAEQHGIAFIHQELNIWPEMTVLENLFIGK EISSKLGVLQTRKMKALAKEQFDKLSVSLSLDQEAGECSVGQQQMIEIAKALMTNAEV IIMDEPTAALTEREISKLFEVITALKKNGVSIVYISHRMEEIFAICDRITIMRDGKTV DTTNISETDFDEVVKKMVGRELTERYPKRTPSLGDKVFEVKNASVKGSFEDVSFYVRS GEIVGVSGLMGAGRTEMMRALFGVDRLDTGEIWIAGKKTAIKNPQEAVKKGLGFITEN RKDEGLLLDTSIRENIALPNLSSFSPKGLIDHKREAEFVDLLIKRLTIKTASPETHAR HLSGGNQQKVVIAKWIGIGPKVLILDEPTRGVDVGAKREIYTLMNELTERGVAIIMVS SELPEILGMSDRIIVVHEGRISGEIHAREATQERIMTLATGGR*" gene 3569280..3570761 /gene="rbsA" /locus_tag="BSU_35940" /old_locus_tag="BSU35940" CDS 3570763..3571731 /gene="rbsC" /locus_tag="BSU_35950" /old_locus_tag="BSU35950" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:7921236, 15849754, 16850406" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7921236, 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="ribose ABC transporter (permease)" /protein_id="NP_391476.1" /db_xref="EnsemblGenomes-Gn:BSU35950" /db_xref="EnsemblGenomes-Tr:CAB15612" /db_xref="GOA:P36948" /db_xref="InterPro:IPR001851" /db_xref="InterPro:IPR035568" /db_xref="SubtiList:BG10880" /db_xref="UniProtKB/Swiss-Prot:P36948" /translation="MKTEQLQTEQKRIHFDGVMQKLGPFLGLFILVIIVSILNPSFLE PLNILNLLRQVAINGLIAFGMTFVILTGGIDLSVGAILALSSALVAGMIVSGVDPVLA IILGCIIGAVLGMINGLLITKGKMAPFIATLATMTVFRGLTLVYTDGNPITGLGTNYG FQMFGRGYFLGIPVPAITMVLAFVILWVLLHKTPFGRRTYAIGGNEKAALISGIKVTR VKVMIYSLAGLLSALAGAILTSRLHSAQPTAGESYELDAIAAVVLGGTSLSGGRGRIV GTLIGVLIIGTLNNGLNLLGVSSFYQLVVKGIVILIAVLLDRKKSA*" gene 3570763..3571731 /gene="rbsC" /locus_tag="BSU_35950" /old_locus_tag="BSU35950" CDS 3571743..3572660 /gene="rbsB" /locus_tag="BSU_35960" /old_locus_tag="BSU35960" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:7921236" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7921236; Product type t : transporter" /codon_start=1 /transl_table=11 /product="ribose ABC transporter (ribose-binding lipoprotein)" /protein_id="NP_391477.1" /db_xref="EnsemblGenomes-Gn:BSU35960" /db_xref="EnsemblGenomes-Tr:CAB15613" /db_xref="GOA:P36949" /db_xref="InterPro:IPR025997" /db_xref="InterPro:IPR028082" /db_xref="SubtiList:BG10881" /db_xref="UniProtKB/Swiss-Prot:P36949" /translation="MKKAVSVILTLSLFLLTACSLEPPQWAKPSNSGNKKEFTIGLSV STLNNPFFVSLKKGIEKEAKKRGMKVIIVDAQNDSSKQTSDVEDLIQQGVDALLINPT DSSAISTAVESANAVGVPVVTIDRSAEQGKVETLVASDNVKGGEMAAAFIADKLGKGA KVAELEGVPGASATRERGSGFHNIADQKLQVVTKQSADFDRTKGLTVMENLLQGHPDI QAVFAHNDEMALGALEAINSSGKDILVIGFDGNKDALASIKDRKLSATVAQQPELIGK LATEAADDILHGKKVQKTISAPLKLETQK*" gene 3571743..3572660 /gene="rbsB" /locus_tag="BSU_35960" /old_locus_tag="BSU35960" promotor_-35 3572669..3572675 /Source="Nicolas_upshift_promotors" /id="U2817" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.99100899100899" /psig="0.99100899100899" /xcortree=144 /SigmaFactorBS="cgcctctcaaactagaaacacaaaaataattgtctgaTGTTT AGgaacctgcgataacGTGAATAGAGATATAGAATgaattatttctcttacgtgagga g" /listShort="ywsB, S1383, ywsA, S1384" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3572690..3572708 /Source="Nicolas_upshift_promotors" /id="U2817" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.99100899100899" /psig="0.99100899100899" /xcortree=144 /SigmaFactorBS="cgcctctcaaactagaaacacaaaaataattgtctgaTGTTT AGgaacctgcgataacGTGAATAGAGATATAGAATgaattatttctcttacgtgagga g" /listShort="ywsB, S1383, ywsA, S1384" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3572692 /Source="Nicolas_upshifts" /id="U2817" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.99100899100899" /psig="0.99100899100899" /xcortree=144 /SigmaFactorBS="cgcctctcaaactagaaacacaaaaataattgtctgaTGTTT AGgaacctgcgataacGTGAATAGAGATATAGAATgaattatttctcttacgtgagga g" /listShort="ywsB, S1383, ywsA, S1384" /GFF_Attribute="listLong" CDS 3572742..3573278 /gene="ywsB" /locus_tag="BSU_35970" /old_locus_tag="BSU35970" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15187182; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative cell wall binding enzyme" /protein_id="NP_391478.1" /db_xref="EnsemblGenomes-Gn:BSU35970" /db_xref="EnsemblGenomes-Tr:CAB15614" /db_xref="GOA:P96729" /db_xref="InterPro:IPR003646" /db_xref="InterPro:IPR036028" /db_xref="SubtiList:BG12530" /db_xref="UniProtKB/Swiss-Prot:P96729" /translation="MNKPTKLFSTLALAAGMTAAAAGGAGTIHAQQPETTVSIDDLYS YPIDSYLVSAEALNVRTKPSASSQKADTLHLGDSLKLISFSNADWAKVKYKNGKTGFV STHYIVKAATTVKTKTKTKVYTSADGKSIKTLPADTSVSFLGWSKTNKGGFDFDWVFV DYGGTTGYMKTKDLHMTK*" gene 3572742..3573278 /gene="ywsB" /locus_tag="BSU_35970" /old_locus_tag="BSU35970" downshifts 3573261 /Source="Nicolas_upshifts" /id="D1857" /incds=0 /nref=187 /ntot=255 /MaxReadThrough="5.87246" /MaxDrop="7.38203" /score="26.4284327" /energy="-19" /TU="U2817" /idTUdmin="U2814" /TUdmin="-3" /isTUend="TRUE" S_feature 3573306..3573416 /Source="Nicolas_S_feature" /locus_tag="new_3707708_3707818" /HighExp="Etha, M9-stat, Sw, M40t90, G150, B60, T0.30H, M0t90, T1.30H, Lbexp" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigB" /TUshortPSig="0.991" /TUlongSig="NA" /TUlongPSig="NA" /label="S1383" promotor_-35 3573385..3573391 /Source="Nicolas_upshift_promotors" /id="U2818" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=889 /SigmaFactorBS="atattgtcgtatgctgtgtcgaaacctTACATGAtcatcgac atttttGTTCACGCTAAAaagcggaggtgtaaatatggatcaatttgaagcagcatat g" /listShort="ywsA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3573406..3573417 /Source="Nicolas_upshift_promotors" /id="U2818" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=889 /SigmaFactorBS="atattgtcgtatgctgtgtcgaaacctTACATGAtcatcgac atttttGTTCACGCTAAAaagcggaggtgtaaatatggatcaatttgaagcagcatat g" /listShort="ywsA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3573418 /Source="Nicolas_upshifts" /id="U2818" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=889 /SigmaFactorBS="atattgtcgtatgctgtgtcgaaacctTACATGAtcatcgac atttttGTTCACGCTAAAaagcggaggtgtaaatatggatcaatttgaagcagcatat g" /listShort="ywsA" /GFF_Attribute="listLong" CDS 3573434..3573730 /gene="ywsA" /locus_tag="BSU_35980" /old_locus_tag="BSU35980" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 11782522" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_391479.1" /db_xref="EnsemblGenomes-Gn:BSU35980" /db_xref="EnsemblGenomes-Tr:CAB15615" /db_xref="InterPro:IPR024997" /db_xref="SubtiList:BG12529" /db_xref="UniProtKB/Swiss-Prot:P96728" /translation="MDQFEAAYESYKARQTTADQENVPSGKEEIIAVRRNEEDNIIAV KTNTGRELDYPTALSEAKSGKLAHVDVFHKYGRDILRSEPDGIKENNLSELPDF*" gene 3573434..3573730 /gene="ywsA" /locus_tag="BSU_35980" /old_locus_tag="BSU35980" S_feature 3573731..3574383 /Source="Nicolas_S_feature" /locus_tag="new_3708133_3708785" /HighExp="Etha, M9-stat, S5, S7, S6, Sw, S8, B60, G150, S4" /AntisenseName="ywrO" /AntisenseCor="-0.23279201478213099" /AntisenseRegPval="-3.9" /CDS_PredictionProba="NA" /TUshortSig="SigB" /TUshortPSig="0.991" /TUlongSig="NA" /TUlongPSig="NA" /label="S1384" CDS complement(3573770..3574297) /gene="ywrO" /locus_tag="BSU_35990" /old_locus_tag="BSU35990" /function="16.8: Protect" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1b: Function from experimental evidences in the studied species; PubMedId: 11782522, 14697229, 17768344; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="nitroreductase (unknown substrate)" /protein_id="NP_391480.1" /db_xref="EnsemblGenomes-Gn:BSU35990" /db_xref="EnsemblGenomes-Tr:CAB15616" /db_xref="GOA:P80871" /db_xref="InterPro:IPR003680" /db_xref="InterPro:IPR029039" /db_xref="SubtiList:BG12528" /db_xref="UniProtKB/Swiss-Prot:P80871" /translation="MKILVLAVHPHMETSVVNKAWAEELSKHDNITVRDLYKEYPDEA IDVAKEQQLCEEYDRIVFQFPLYWYSSPPLLKKWQDLVLTYGWAFGSEGNALHGKELM LAVSTGSEAEKYQAGGANHYSISELLKPFQATSNLIGMKYLPPYVFYGVNYAAAEDIS HSAKRLAEYIQQPFV*" gene complement(3573770..3574297) /gene="ywrO" /locus_tag="BSU_35990" /old_locus_tag="BSU35990" downshifts complement(3573780) /Source="Nicolas_upshifts" /id="D1858" /incds=0 /nref=48 /ntot=208 /MaxReadThrough="3.48831" /MaxDrop="4.56453" /score="1.41593376" /energy="-17.4" /TU="U2819" /idTUdmin="U2821" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(3574317..3574336) /Source="Nicolas_upshift_promotors" /id="U2819" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.603396603396603" /psig=1 /xcortree=1963 /SigmaFactorBS="aaaagaaagccccttttagcagggctttcttttTATTTGGCt cttttcctgattTTAGATAAAATAACATCAAAacagtaaaggtgtggtctgatgaaaa t" /listShort="ywrO" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3574330) /Source="Nicolas_upshifts" /id="U2819" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.603396603396603" /psig=1 /xcortree=1963 /SigmaFactorBS="aaaagaaagccccttttagcagggctttcttttTATTTGGCt cttttcctgattTTAGATAAAATAACATCAAAacagtaaaggtgtggtctgatgaaaa t" /listShort="ywrO" /GFF_Attribute="listLong" downshifts 3574341 /Source="Nicolas_upshifts" /id="D1859" /incds=0 /nref=26 /ntot=56 /MaxReadThrough="0.805200000000001" /MaxDrop="4.7199" /score="10.409416" /energy="-6.8" /TU="NA" /idTUdmin="U2817" /TUdmin="-1" /isTUend="TRUE" promotor_-35 complement(3574350..3574357) /Source="Nicolas_upshift_promotors" /id="U2819" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.603396603396603" /psig=1 /xcortree=1963 /SigmaFactorBS="aaaagaaagccccttttagcagggctttcttttTATTTGGCt cttttcctgattTTAGATAAAATAACATCAAAacagtaaaggtgtggtctgatgaaaa t" /listShort="ywrO" /GFF_Attribute="listLong" /label="promotor_-35" downshifts complement(3574396) /Source="Nicolas_upshifts" /id="D1860" /incds=0 /nref=20 /ntot=149 /MaxReadThrough="4.85403" /MaxDrop="6.46739" /score="-8.02974492" /energy="-5" /TU="U2821" /idTUdmin="U2821" /TUdmin="-616" /isTUend="FALSE" CDS complement(3574397..3575164) /gene="alsD" /locus_tag="BSU_36000" /old_locus_tag="BSU36000" /EC_number="4.1.1.5" /function="16.8: Protect" /function="16.14: Store" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:7685336, 10972805, 12363365, 17183216, 21531833, 26454865" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7685336, 10972805, 12363365, 17183216, 21531833, 26454865; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="alpha-acetolactate decarboxylase" /protein_id="NP_391481.1" /db_xref="EnsemblGenomes-Gn:BSU36000" /db_xref="EnsemblGenomes-Tr:CAB15617" /db_xref="GOA:Q04777" /db_xref="InterPro:IPR005128" /db_xref="SubtiList:BG10472" /db_xref="UniProtKB/Swiss-Prot:Q04777" /translation="MKRESNIQVLSRGQKDQPVSQIYQVSTMTSLLDGVYDGDFELSE IPKYGDFGIGTFNKLDGELIGFDGEFYRLRSDGTATPVQNGDRSPFCSFTFFTPDMTH KIDAKMTREDFEKEINSMLPSRNLFYAIRIDGLFKKVQTRTVELQEKPYVPMVEAVKT QPIFNFDNVRGTIVGFLTPAYANGIAVSGYHLHFIDEGRNSGGHVFDYVLEDCTVTIS QKMNMNLRLPNTADFFNANLDNPDFAKDIETTEGSPE*" gene complement(3574397..3575164) /gene="alsD" /locus_tag="BSU_36000" /old_locus_tag="BSU36000" CDS complement(3575226..3576938) /gene="alsS" /locus_tag="BSU_36010" /old_locus_tag="BSU36010" /EC_number="2.2.1.6" /function="16.8: Protect" /function="16.14: Store" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:10972805, 12363365, 17183216, 7685336, 25393087, 25355936" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10972805, 12363365, 17183216, 7685336, 25393087, 25355936; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="alpha-acetolactate synthase" /protein_id="NP_391482.2" /db_xref="EnsemblGenomes-Gn:BSU36010" /db_xref="EnsemblGenomes-Tr:CAB15618" /db_xref="GOA:Q04789" /db_xref="InterPro:IPR000399" /db_xref="InterPro:IPR011766" /db_xref="InterPro:IPR012000" /db_xref="InterPro:IPR012001" /db_xref="InterPro:IPR012782" /db_xref="InterPro:IPR029035" /db_xref="InterPro:IPR029061" /db_xref="SubtiList:BG10471" /db_xref="UniProtKB/Swiss-Prot:Q04789" /translation="MTKATKEQKSLVKNRGAELVVDCLVEQGVTHVFGIPGAKIDAVF DALQDKGPEIIVARHEQNAAFMAQAVGRLTGKPGVVLVTSGPGASNLATGLLTANTEG DPVVALAGNVIRADRLKRTHQSLDNAALFQPITKYSVEVQDVKNIPEAVTNAFRIASA GQAGAAFVSFPQDVVNEVTNTKNVRAVAAPKLGPAADDAISAAIAKIQTAKLPVVLVG MKGGRPEAIKAVRKLLKKVQLPFVETYQAAGTLSRDLEDQYFGRIGLFRNQPGDLLLE QADVVLTIGYDPIEYDPKFWNINGDRTIIHLDEIIADIDHAYQPDLELIGDIPSTINH IEHDAVKVEFAEREQKILSDLKQYMHEGEQVPADWKSDRAHPLEIVKELRNAVDDHVT VTCDIGSHAIWMSRYFRSYEPLTLMISNGMQTLGVALPWAIGASLVKPGEKVVSVSGD GGFLFSAMELETAVRLKAPIVHIVWNDSTYDMVAFQQLKKYNRTSAVDFGNIDIVKYA ESFGATGLRVESPDQLADVLRQGMNAEGPVIIDVPVDYSDNINLASDKLPKEFGELMK TKAL*" gene complement(3575226..3576938) /gene="alsS" /locus_tag="BSU_36010" /old_locus_tag="BSU36010" promotor_-35 3575837..3575846 /Source="Nicolas_upshift_promotors" /id="U2820" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1377 /SigmaFactorBS="acgatttcaagagggtgcgctctgtctgatttccaatCTGCA GGCACctgctcaccttcaTGCATATATTGTTTTAAATCagaaaggattttctgctcac g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3575860..3575879 /Source="Nicolas_upshift_promotors" /id="U2820" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1377 /SigmaFactorBS="acgatttcaagagggtgcgctctgtctgatttccaatCTGCA GGCACctgctcaccttcaTGCATATATTGTTTTAAATCagaaaggattttctgctcac g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3575860 /Source="Nicolas_upshifts" /id="U2820" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1377 /SigmaFactorBS="acgatttcaagagggtgcgctctgtctgatttccaatCTGCA GGCACctgctcaccttcaTGCATATATTGTTTTAAATCagaaaggattttctgctcac g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 complement(3576992..3577011) /Source="Nicolas_upshift_promotors" /id="U2821" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.544455544455544" /psig="0.993006993006993" /xcortree=1577 /SigmaFactorBS="tacatattaatcataaggcgaatcgatATTGGaggtcaattt ccaaAGAGTGTATAGTGAAACTTAtcacaagatatttaaaattttacgtttaaaatgc a" /listShort="alsS, alsD, ywrO" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3576997) /Source="Nicolas_upshifts" /id="U2821" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.544455544455544" /psig="0.993006993006993" /xcortree=1577 /SigmaFactorBS="tacatattaatcataaggcgaatcgatATTGGaggtcaattt ccaaAGAGTGTATAGTGAAACTTAtcacaagatatttaaaattttacgtttaaaatgc a" /listShort="alsS, alsD, ywrO" /GFF_Attribute="listLong" promotor_-35 3577017..3577024 /Source="Nicolas_upshift_promotors" /id="U2822" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.498501498501498" /psig="0.985014985014985" /xcortree=99 /SigmaFactorBS="gtgataagtttcactatacactctttggaAATTGACCtccaa tatcgattCGCCTTATGATTAATATGTAatacgaattattaacctatggaaaggaatg c" /listShort="alsR, S1385" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 complement(3577026..3577030) /Source="Nicolas_upshift_promotors" /id="U2821" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.544455544455544" /psig="0.993006993006993" /xcortree=1577 /SigmaFactorBS="tacatattaatcataaggcgaatcgatATTGGaggtcaattt ccaaAGAGTGTATAGTGAAACTTAtcacaagatatttaaaattttacgtttaaaatgc a" /listShort="alsS, alsD, ywrO" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3577038..3577057 /Source="Nicolas_upshift_promotors" /id="U2822" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.498501498501498" /psig="0.985014985014985" /xcortree=99 /SigmaFactorBS="gtgataagtttcactatacactctttggaAATTGACCtccaa tatcgattCGCCTTATGATTAATATGTAatacgaattattaacctatggaaaggaatg c" /listShort="alsR, S1385" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3577048 /Source="Nicolas_upshifts" /id="U2822" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.498501498501498" /psig="0.985014985014985" /xcortree=99 /SigmaFactorBS="gtgataagtttcactatacactctttggaAATTGACCtccaa tatcgattCGCCTTATGATTAATATGTAatacgaattattaacctatggaaaggaatg c" /listShort="alsR, S1385" /GFF_Attribute="listLong" CDS 3577096..3578004 /gene="alsR" /locus_tag="BSU_36020" /old_locus_tag="BSU36020" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:10809684, 10972805, 12363365, 15978075, 17183216, 7685336, 22178965, 23576037, 23695583, 23836140" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10809684, 10972805, 12363365, 15978075, 17183216, 7685336, 22178965, 23576037, 23695583, 23836140; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator controlling alsSD, ictEP expression (LysR family)" /protein_id="NP_391483.1" /db_xref="EnsemblGenomes-Gn:BSU36020" /db_xref="EnsemblGenomes-Tr:CAB15619" /db_xref="GOA:Q04778" /db_xref="InterPro:IPR000847" /db_xref="InterPro:IPR005119" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG10470" /db_xref="UniProtKB/Swiss-Prot:Q04778" /translation="MELRHLQYFIAVAEELHFGKAARRLNMTQPPLSQQIKQLEEEVG VTLLKRTKRFVELTAAGEIFLNHCRMALMQIGQGIELAQRTARGEQGLLVIGFVGSAT YEFLPPIVREYRKKFPSVKIELREISSSRQQEELLKGNIDIGILHPPLQHTALHIETA QSSPCVLALPKQHPLTSKESITIEDLRDEPIITVAKEAWPTLYMDFIQFCEQAGFRPN IVQEATEYQMVIGLVSAGIGMTFVPSSAKKLFNLDVTYRKMDQIQLNAEWVIAYRKDN HNPLIKHFIHISNCQQTRTKESDAGT*" gene 3577096..3578004 /gene="alsR" /locus_tag="BSU_36020" /old_locus_tag="BSU36020" promotor_-35 3578072..3578080 /Source="Nicolas_upshift_promotors" /id="U2823" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.896103896103896" /psig="0.896103896103896" /xcortree=1419 /SigmaFactorBS="ttttttcttttgggattcttatggaatttttattaatttaat ataatcgcTTAGTACAActttatatcagtaTACGTATACATACAGTACAAatagttgg c" /listShort="S1385, ywrK" /GFF_Attribute="listLong" /label="promotor_-35" S_feature 3578082..3578214 /Source="Nicolas_S_feature" /locus_tag="new_3712484_3712616" /HighExp="BT, S8, B36, S7, G/S, S6, Pyr, B60, Etha, Glucon" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.14666000000000001" /TUshortSig="SigK, SigA" /TUshortPSig="0.896, 0.985" /TUlongSig="NA" /TUlongPSig="NA" /label="S1385" upshifts 3578082 /Source="Nicolas_upshifts" /id="U2823" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.896103896103896" /psig="0.896103896103896" /xcortree=1419 /SigmaFactorBS="ttttttcttttgggattcttatggaatttttattaatttaat ataatcgcTTAGTACAActttatatcagtaTACGTATACATACAGTACAAatagttgg c" /listShort="S1385, ywrK" /GFF_Attribute="listLong" promotor_-10 3578094..3578113 /Source="Nicolas_upshift_promotors" /id="U2823" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.896103896103896" /psig="0.896103896103896" /xcortree=1419 /SigmaFactorBS="ttttttcttttgggattcttatggaatttttattaatttaat ataatcgcTTAGTACAActttatatcagtaTACGTATACATACAGTACAAatagttgg c" /listShort="S1385, ywrK" /GFF_Attribute="listLong" /label="promotor_-10" CDS 3578215..3579543 /gene="ywrK" /locus_tag="BSU_36030" /old_locus_tag="BSU36030" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative Na+/H+ antiporter" /protein_id="NP_391484.1" /db_xref="EnsemblGenomes-Gn:BSU36030" /db_xref="EnsemblGenomes-Tr:CAB15620" /db_xref="GOA:O05224" /db_xref="InterPro:IPR000802" /db_xref="SubtiList:BG12527" /db_xref="UniProtKB/Swiss-Prot:O05224" /translation="MLAFFVTMIFIFWRPKGLNEAIPATFGALMVLLCGSVSLADLGE IGTKVTGASVTILATMIMAIALESFGFFYWVAAKLLQQSKGSGIKLFWLTNLLCFLMT IFLNNDGSILITTPILLLVLKYLGLKKHQKAPYLLSGVLIATASSAPIGVSNIVNLIS LKIIGMDLYLHTAMMFVPSMMGLIFMTCLLFMFFYKRLPKSLPDIPGHFQSLRHRRYH PLHSPSAPLPERNQTKIMLFVLAFVFLVRMSLFAASYTGISVPLVAVIGSFILLSWRW IYFKTSPRDLLYKSPWHIFIFAFTMYVLIYGLHNIGFTELLVSYFEPVVSGSLAHATF ASGISTSVFSNLFNNHPALMISTFTLTEMTLNPSTTKIIYLANIIGSDIGSLLLPMGT LATLIWMHILKQHDESISWGEYIKTTIIIIPLTVLFTLTCLYFWISWLFL*" gene 3578215..3579543 /gene="ywrK" /locus_tag="BSU_36030" /old_locus_tag="BSU36030" downshifts 3579534 /Source="Nicolas_upshifts" /id="D1861" /incds=0 /nref=16 /ntot=32 /MaxReadThrough="1.63489" /MaxDrop="6.12455" /score="-6.14091334" /energy="-11.9" /TU="NA" /idTUdmin="U2823" /TUdmin=0 /isTUend="TRUE" CDS complement(3579600..3580277) /gene="ywrJ" /locus_tag="BSU_36040" /old_locus_tag="BSU36040" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 14762006, 22882546" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_391485.1" /db_xref="EnsemblGenomes-Gn:BSU36040" /db_xref="EnsemblGenomes-Tr:CAB15621" /db_xref="InterPro:IPR020139" /db_xref="InterPro:IPR020173" /db_xref="SubtiList:BG12526" /db_xref="UniProtKB/Swiss-Prot:O05223" /translation="MKGLNQFLNTDVEVVISGDTRFVGTLIDIGQDIFVIFDGCNYLY IPLLHLHQINKAKIVTSTEKPFLINPEDPMIEAETQAFSYRNTLNKVKGQFIEVYVTG GRSIHGYVTNVLNDYIVFFSPVFKILFISMHHLKWFTPYSTEQTPYTLDNSQLPVVPS KVPLVRNFEEQIKKNIGELVIFDMGEVPEKVGLLKGVSNNIIELINASGEPVIWKLNH LKTMHLP*" gene complement(3579600..3580277) /gene="ywrJ" /locus_tag="BSU_36040" /old_locus_tag="BSU36040" downshifts complement(3579610) /Source="Nicolas_upshifts" /id="D1862" /incds=0 /nref=14 /ntot=28 /MaxReadThrough="1.74629" /MaxDrop="5.1172" /score="-4.02447737" /energy="-9.5" /TU="NA" /idTUdmin="U2824" /TUdmin=0 /isTUend="TRUE" CDS complement(3580337..3581479) /gene="cotB" /locus_tag="BSU_36050" /old_locus_tag="BSU36050" /function="16.8: Protect" /function="16.13: Shape" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:8755863, 10559171, 11737650, 14762006, 19933362, 27185916" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8755863, 10559171, 11737650, 14762006, 19933362, 27185916; Product type s : structure" /codon_start=1 /transl_table=11 /product="spore coat protein (outer)" /protein_id="NP_391486.1" /db_xref="EnsemblGenomes-Gn:BSU36050" /db_xref="EnsemblGenomes-Tr:CAB15622" /db_xref="GOA:P07789" /db_xref="SubtiList:BG10491" /db_xref="UniProtKB/Swiss-Prot:P07789" /translation="MSKRRMKYHSNNEISYYNFLHSMKDKIVTVYRGGPESKKGKLTA VKSDYIALQAEKKIIYYQLEHVKSITEDTNNSTTTIETEEMLDADDFHSLIGHLINQS VQFNQGGPESKKGRLVWLGDDYAALNTNEDGVVYFNIHHIKSISKHEPDLKIEEQTPV GVLEADDLSEVFKSLTHKWVSINRGGPEAIEGILVDNADGHYTIVKNQEVLRIYPFHI KSISLGPKGSYKKEDQKNEQNQEDNNDKDSNSFISSKSYSSSKSSKRSLKSSDDQSSK SGRSSRSKSSSKSSKRSLKSSDYQSSKSGRSSRSKSSSKSSKRSLKSSDYQSSKSSKR SPRSSDYQSSRSPGYSSSIKSSGKQKEDYSYETIVRTIDYHWKRKF*" gene complement(3580337..3581479) /gene="cotB" /locus_tag="BSU_36050" /old_locus_tag="BSU36050" promotor_-10 complement(3581516..3581535) /Source="Nicolas_upshift_promotors" /id="U2824" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp="0.932067932067932" /psig="0.932067932067932" /xcortree=1302 /SigmaFactorBS="ggaaaaagcgacaattaggctattgaaTTAGTTCAAcaaata aatgtgaCACGTATATATGCAGTATGTttatcatctatgtataagtgactaggaggaa t" /listShort="cotB, ywrJ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3581524) /Source="Nicolas_upshifts" /id="U2824" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp="0.932067932067932" /psig="0.932067932067932" /xcortree=1302 /SigmaFactorBS="ggaaaaagcgacaattaggctattgaaTTAGTTCAAcaaata aatgtgaCACGTATATATGCAGTATGTttatcatctatgtataagtgactaggaggaa t" /listShort="cotB, ywrJ" /GFF_Attribute="listLong" S_feature complement(3581526..3581606) /Source="Nicolas_S_feature" /locus_tag="new_3715928_3716008_c" /HighExp="S6, S7, S8, S5, BT, B36, S4, G/S, Pyr, S3" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="Sig-, SigK" /TUshortPSig="0.142, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S1386" promotor_-35 complement(3581549..3581557) /Source="Nicolas_upshift_promotors" /id="U2824" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp="0.932067932067932" /psig="0.932067932067932" /xcortree=1302 /SigmaFactorBS="ggaaaaagcgacaattaggctattgaaTTAGTTCAAcaaata aatgtgaCACGTATATATGCAGTATGTttatcatctatgtataagtgactaggaggaa t" /listShort="cotB, ywrJ" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3581607..3582695) /gene="cotH" /locus_tag="BSU_36060" /old_locus_tag="BSU36060" /function="16.13: Shape" /function="16.5: Explore" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:14762006, 25115591, 27185916" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 14762006, 25115591, 27185916; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="spore coat protein kinase" /protein_id="NP_391487.1" /db_xref="EnsemblGenomes-Gn:BSU36060" /db_xref="EnsemblGenomes-Tr:CAB15623" /db_xref="GOA:Q45535" /db_xref="InterPro:IPR014867" /db_xref="SubtiList:BG11791" /db_xref="UniProtKB/Swiss-Prot:Q45535" /translation="MKNQSNLPLYQLFVHPKDLRELKKDIWDDDPVPAVMKVNQKRLD IDIAYRGSHIRDFKKKSYHISFYQPKTFRGAREIHLNAEYKDPSLMRNKLSLDFFSEL GTLSPKAEFAFVKMNGKNEGVYLELESVDEYYLAKRKLADGAIFYAVDDDANFSLMSD LERETKTSLELGYEKKTGTEEDDFYLQDMIFKINTVPKAQFKSEVTKHVDVDKYLRWL AGIVFTSNYDGFVHNYALYRSGETGLFEVIPWDYDATWGRDIHGERMAADYVRIQGFN TLTARILDESEFRKSYKRLLEKTLQSLFTIEYMEPKIMAMYERIRPFVLMDPYKKNDI ERFDREPDVICEYIKNRSQYLKDHLSIL*" gene complement(3581607..3582695) /gene="cotH" /locus_tag="BSU_36060" /old_locus_tag="BSU36060" S_feature complement(3582696..3582809) /Source="Nicolas_S_feature" /locus_tag="new_3717098_3717211_c" /HighExp="S6, S8, S7, S5, BT, B36, Pyr, G/S, S4, B60" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="Sig-, SigK" /TUshortPSig="0.142, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S1387" promotor_-35 3582751..3582760 /Source="Nicolas_upshift_promotors" /id="U2825" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp="0.99000999000999" /psig="0.99000999000999" /xcortree=1411 /SigmaFactorBS="tatttttataagatctcagcggaacACTTATACACtttttaa aaccgCGCGTACTATGAGGGTAGTAaggatcttcatccttaacatatttttaaaagga g" /listShort="cotG" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3582773..3582792 /Source="Nicolas_upshift_promotors" /id="U2825" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp="0.99000999000999" /psig="0.99000999000999" /xcortree=1411 /SigmaFactorBS="tatttttataagatctcagcggaacACTTATACACtttttaa aaccgCGCGTACTATGAGGGTAGTAaggatcttcatccttaacatatttttaaaagga g" /listShort="cotG" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3582786 /Source="Nicolas_upshifts" /id="U2825" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp="0.99000999000999" /psig="0.99000999000999" /xcortree=1411 /SigmaFactorBS="tatttttataagatctcagcggaacACTTATACACtttttaa aaccgCGCGTACTATGAGGGTAGTAaggatcttcatccttaacatatttttaaaagga g" /listShort="cotG" /GFF_Attribute="listLong" upshifts complement(3582809) /Source="Nicolas_upshifts" /id="U2826" /multdbtbs="SigK" /comp="M15" /sig="Sig-" /pcomp="0.817182817182817" /psig="0.141858141858142" /xcortree=1262 /SigmaFactorBS="cttcttcgatgtcagaatgggaatagtggCCCAAtttgaaat CCTCCTTTTAAAAATatgttaaggatgaagatccttactaccctcatagtacgcgcgg t" /listShort="S1387, cotH, S1386, cotB, ywrJ" /GFF_Attribute="listLong" promotor_-10 complement(3582813..3582827) /Source="Nicolas_upshift_promotors" /id="U2826" /multdbtbs="SigK" /comp="M15" /sig="Sig-" /pcomp="0.817182817182817" /psig="0.141858141858142" /xcortree=1262 /SigmaFactorBS="cttcttcgatgtcagaatgggaatagtggCCCAAtttgaaat CCTCCTTTTAAAAATatgttaaggatgaagatccttactaccctcatagtacgcgcgg t" /listShort="S1387, cotH, S1386, cotB, ywrJ" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 complement(3582836..3582840) /Source="Nicolas_upshift_promotors" /id="U2826" /multdbtbs="SigK" /comp="M15" /sig="Sig-" /pcomp="0.817182817182817" /psig="0.141858141858142" /xcortree=1262 /SigmaFactorBS="cttcttcgatgtcagaatgggaatagtggCCCAAtttgaaat CCTCCTTTTAAAAATatgttaaggatgaagatccttactaccctcatagtacgcgcgg t" /listShort="S1387, cotH, S1386, cotB, ywrJ" /GFF_Attribute="listLong" /label="promotor_-35" CDS 3582836..3583423 /gene="cotG" /locus_tag="BSU_36070" /old_locus_tag="BSU36070" /function="16.13: Shape" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:11737650, 14762006, 15621419, 22720735, 25115591, 27185916" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11737650, 14762006, 15621419, 22720735, 25115591, 27185916; Product type cp : cell process" /codon_start=1 /transl_table=11 /product="spore morphogenetic protein" /protein_id="NP_391488.1" /db_xref="EnsemblGenomes-Gn:BSU36070" /db_xref="EnsemblGenomes-Tr:CAB15624" /db_xref="GOA:P39801" /db_xref="SubtiList:BG11017" /db_xref="UniProtKB/Swiss-Prot:P39801" /translation="MGHYSHSDIEEAVKSAKKEGLKDYLYQEPHGKKRSHKKSHRTHK KSRSHKKSYCSHKKSRSHKKSFCSHKKSRSHKKSYCSHKKSRSHKKSYRSHKKSRSYK KSYRSYKKSRSYKKSCRSYKKSRSYKKSYCSHKKKSRSYKKSCRTHKKSYRSHKKYYK KPHHHCDDYKRHDDYDSKKEYWKDGNCWVVKKKYK*" gene 3582836..3583423 /gene="cotG" /locus_tag="BSU_36070" /old_locus_tag="BSU36070" CDS 3582924..3583403 /locus_tag="BSU_36079" /old_locus_tag="BSU36079" /function="14.1: Surface structures" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="doubtful CDS (putative in frame frameshift)" /protein_id="YP_009514005.1" /translation="MEKNAVIKSRTALTKNLAAIKNHTALTKNLAVTKNHSVLTKNLA ATKNHTALTRNLAATKNRTVLTKNLAAIKNLTVLTKNLVAIKNLAVLTKNLAATKSLT VLTRKNLAAIRSHAAHTKNLIVPIRNTTKNRTTTATTTKDTMIMTAKKNTGKTAIAG* " gene 3582924..3583403 /locus_tag="BSU_36079" /old_locus_tag="BSU36079" S_feature complement(3583307..3583504) /Source="Nicolas_S_feature" /locus_tag="new_3717709_3717906_c" /HighExp="S5, S6, S4, B60, S3, nit, G/S, SMMPr, S8, ferm" /AntisenseName="cotG" /AntisenseCor="0.60092819988141299" /AntisenseRegPval="-27.1" /CDS_PredictionProba="NA" /TUshortSig="SigK" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1388" downshifts 3583340 /Source="Nicolas_upshifts" /id="D1863" /incds=1 /nref=1 /ntot=54 /MaxReadThrough="7.80801" /MaxDrop="2.7794" /score="17.1895651" /energy="-10.7" /TU="U2825" /idTUdmin="U2825" /TUdmin="-154" /isTUend="FALSE" downshifts complement(3583350) /Source="Nicolas_upshifts" /id="D1864" /incds=1 /nref=3 /ntot=23 /MaxReadThrough="4.99409" /MaxDrop="6.67733" /score="-1.37249416" /energy="-5.2" /TU="U2827" /idTUdmin="U2824" /TUdmin="-3740" /isTUend="FALSE" downshifts 3583409 /Source="Nicolas_upshifts" /id="D1865" /incds=0 /nref=41 /ntot=80 /MaxReadThrough="4.68169" /MaxDrop="5.35584" /score="17.1895651" /energy="-10.7" /TU="U2825" /idTUdmin="U2825" /TUdmin="-85" /isTUend="FALSE" downshifts 3583488 /Source="Nicolas_upshifts" /id="D1866" /incds=0 /nref=4 /ntot=17 /MaxReadThrough="2.30708" /MaxDrop="3.92552" /score="17.1895651" /energy="-10.7" /TU="NA" /idTUdmin="U2825" /TUdmin="-6" /isTUend="TRUE" promotor_-10 complement(3583503..3583522) /Source="Nicolas_upshift_promotors" /id="U2827" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1268 /SigmaFactorBS="accttgattataacgaaatggtttaAAGGAAACCAaatgatg cgggtTGCATATGTTATGTCATGACatatatctaatacagggcaaataaaaaaatagg c" /listShort="S1388, S1387, cotH, S1386, cotB, ywrJ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3583509) /Source="Nicolas_upshifts" /id="U2827" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1268 /SigmaFactorBS="accttgattataacgaaatggtttaAAGGAAACCAaatgatg cgggtTGCATATGTTATGTCATGACatatatctaatacagggcaaataaaaaaatagg c" /listShort="S1388, S1387, cotH, S1386, cotB, ywrJ" /GFF_Attribute="listLong" promotor_-35 3583531..3583538 /Source="Nicolas_upshift_promotors" /id="U2828" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.955044955044955" /psig=1 /xcortree=1941 /SigmaFactorBS="atatgtcatgacataacatatgcaacccgcatCATTTGGTtt cctttaaaccatTTCGTTATAATCAAGGTATCctaacgataaaggcggttgttgctat g" /listShort="ywrF, S1389, ywrE" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 complement(3583535..3583544) /Source="Nicolas_upshift_promotors" /id="U2827" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1268 /SigmaFactorBS="accttgattataacgaaatggtttaAAGGAAACCAaatgatg cgggtTGCATATGTTATGTCATGACatatatctaatacagggcaaataaaaaaatagg c" /listShort="S1388, S1387, cotH, S1386, cotB, ywrJ" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3583553..3583572 /Source="Nicolas_upshift_promotors" /id="U2828" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.955044955044955" /psig=1 /xcortree=1941 /SigmaFactorBS="atatgtcatgacataacatatgcaacccgcatCATTTGGTtt cctttaaaccatTTCGTTATAATCAAGGTATCctaacgataaaggcggttgttgctat g" /listShort="ywrF, S1389, ywrE" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3583559 /Source="Nicolas_upshifts" /id="U2828" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.955044955044955" /psig=1 /xcortree=1941 /SigmaFactorBS="atatgtcatgacataacatatgcaacccgcatCATTTGGTtt cctttaaaccatTTCGTTATAATCAAGGTATCctaacgataaaggcggttgttgctat g" /listShort="ywrF, S1389, ywrE" /GFF_Attribute="listLong" CDS 3583597..3584214 /gene="ywrF" /locus_tag="BSU_36080" /old_locus_tag="BSU36080" /EC_number="1.14.13.-" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative flavin-binding monooxygenase" /protein_id="NP_391489.1" /db_xref="EnsemblGenomes-Gn:BSU36080" /db_xref="EnsemblGenomes-Tr:CAB15625" /db_xref="GOA:O05220" /db_xref="InterPro:IPR002563" /db_xref="InterPro:IPR012349" /db_xref="SubtiList:BG12525" /db_xref="UniProtKB/Swiss-Prot:O05220" /translation="MYIFQADQLSAKDTYKLLSGTVIPRPIAFVTTLSSGGAVNAAPF SFYNVVSSDPPLLSISVNRTEGRQKDTARNAVENGEFVVHVSDEAIIEDINETAASLR PDESELTRTSLHPVESKAVSVPGIKEARVRFECKLERHITFDNDQGITTADLLIGRVV CFHLDEKVYDAEKGYILTDELKPASRLAGNHYAKLGEEFTLIRPS*" gene 3583597..3584214 /gene="ywrF" /locus_tag="BSU_36080" /old_locus_tag="BSU36080" S_feature 3584215..3584315 /Source="Nicolas_S_feature" /locus_tag="new_3718617_3718717" /HighExp="Etha, dia5, Diami, dia15, Lbtran, LBGtran, LPhT, M40t45, M40t90, M0t90" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1389" downshifts 3584272 /Source="Nicolas_upshifts" /id="D1867" /incds=0 /nref=11 /ntot=56 /MaxReadThrough="4.52989" /MaxDrop="4.48979" /score="-1.9002322" /energy="-14.9" /TU="U2828" /idTUdmin="U2828" /TUdmin="-454" /isTUend="FALSE" promotor_-35 3584341..3584350 /Source="Nicolas_upshift_promotors" /id="U2829" /multdbtbs="SigW" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1701 /SigmaFactorBS="aaaaagaacacccagagcaagctcggggtgttcttttaTGAA ACGTTTttcctttttctTCGTATAAAGGTAGATtaggaggaattggaatgacaaactt t" /listShort="ywrE, S1390, ywrC, ywrB, ywrA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3584362..3584377 /Source="Nicolas_upshift_promotors" /id="U2829" /multdbtbs="SigW" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1701 /SigmaFactorBS="aaaaagaacacccagagcaagctcggggtgttcttttaTGAA ACGTTTttcctttttctTCGTATAAAGGTAGATtaggaggaattggaatgacaaactt t" /listShort="ywrE, S1390, ywrC, ywrB, ywrA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3584363 /Source="Nicolas_upshifts" /id="U2829" /multdbtbs="SigW" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1701 /SigmaFactorBS="aaaaagaacacccagagcaagctcggggtgttcttttaTGAA ACGTTTttcctttttctTCGTATAAAGGTAGATtaggaggaattggaatgacaaactt t" /listShort="ywrE, S1390, ywrC, ywrB, ywrA" /GFF_Attribute="listLong" CDS 3584392..3584727 /gene="ywrE" /locus_tag="BSU_36090" /old_locus_tag="BSU36090" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_391490.1" /db_xref="EnsemblGenomes-Gn:BSU36090" /db_xref="EnsemblGenomes-Tr:CAB15626" /db_xref="GOA:O05219" /db_xref="InterPro:IPR025441" /db_xref="SubtiList:BG12524" /db_xref="UniProtKB/Swiss-Prot:O05219" /translation="MTNFWILMLIAITISLASQFFIKKKYGIDKSGWRYKHVSNTHKW IEITLLILFVFSLSFFPVEYLLLLFFIVIDSIRIFMEWHYRPEDKQYMYHIVEVSLMF MLLIYVCTL*" gene 3584392..3584727 /gene="ywrE" /locus_tag="BSU_36090" /old_locus_tag="BSU36090" promotor_-10 complement(3584683..3584701) /Source="Nicolas_upshift_promotors" /id="U2830" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.984015984015984" /psig="0.984015984015984" /xcortree=1203 /SigmaFactorBS="ggagcggctgtggggatttaaataactatagGGTACAaacat aaatcaaaaGCATAAACATAAGGGAGACctctacaatgtggtacatatactgtttatc t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3584692) /Source="Nicolas_upshifts" /id="U2830" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.984015984015984" /psig="0.984015984015984" /xcortree=1203 /SigmaFactorBS="ggagcggctgtggggatttaaataactatagGGTACAaacat aaatcaaaaGCATAAACATAAGGGAGACctctacaatgtggtacatatactgtttatc t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(3584716..3584721) /Source="Nicolas_upshift_promotors" /id="U2830" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.984015984015984" /psig="0.984015984015984" /xcortree=1203 /SigmaFactorBS="ggagcggctgtggggatttaaataactatagGGTACAaacat aaatcaaaaGCATAAACATAAGGGAGACctctacaatgtggtacatatactgtttatc t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 3584726 /Source="Nicolas_upshifts" /id="D1868" /incds=0 /nref=5 /ntot=153 /MaxReadThrough="5.64855" /MaxDrop="3.64569" /score="-1.9002322" /energy="-14.9" /TU="U2829" /idTUdmin="U2828" /TUdmin=0 /isTUend="TRUE" CDS complement(3584732..3586309) /gene="hpxW" /locus_tag="BSU_36100" /old_locus_tag="BSU36100" /EC_number="3.5.1.126" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 12823818, 14762019, 19935659, 27303801, 28032445; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="oxamate amidohydrolase" /protein_id="NP_391491.1" /db_xref="EnsemblGenomes-Gn:BSU36100" /db_xref="EnsemblGenomes-Tr:CAB15627" /db_xref="GOA:O05218" /db_xref="InterPro:IPR000101" /db_xref="InterPro:IPR029055" /db_xref="SubtiList:BG12523" /db_xref="UniProtKB/Swiss-Prot:O05218" /translation="MNKSVIGTKQMVVSPHYLASQAGNRILDKGGNAFDAAVAVSACL AVVYPHMTGLGGDSFWLTFHQETKAVKVYNGSGRSGKNVTRDVYKGKSAIPLRGIDSA ITVPGMVDSWDAVLKEYGRLSLADVLEPARDYAQNGFPVSADQCRHTEKNIELLASTP YTADIFTRRGKAPVPGERFVQKELADSLNLIAEKGRSAFYEGDLAQRIVSHLQNNGSY MTIDDFKAHRGEWAAPVSSDYRGYSVYQAPPNSQGFTGLLTLNILENYDFTQIEHGSF EYYHVLVEALKKSFLDRDAVLTDPAFADIPLERLLDKRYAKQLAEEIGYLAIPAESRP VGSDTAYAAVIDADGNAVSFIQSLYFEFGSAVTAGDTGILLQNRGSFFSLDENHVNTL EPRKRTFHTLMPAMVCKGGKPKILYGTQGGEGQPQTQTAIITRMLDYGMHPQQAISEP RWVWGRTWGEEYEGLRVEGRFTDKTIQKLKDSGHLVEVVGDYDPLMGQAAAIKVDEEG FLQGGADPRGDGAAVGI*" gene complement(3584732..3586309) /gene="hpxW" /locus_tag="BSU_36100" /old_locus_tag="BSU36100" S_feature 3584771..3586482 /Source="Nicolas_S_feature" /locus_tag="new_3719173_3720884" /HighExp="T1.0H, T0.30H, T1.30H, T2.0H, T2.30H, T3.30H, T3.0H, T-0.40H, T0.0H, Salt" /AntisenseName="ywrD" /AntisenseCor="0.153519829066777" /AntisenseRegPval="-1.9" /CDS_PredictionProba="NA" /TUshortSig="SigWXY" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1390" promotor_-35 3586460..3586467 /Source="Nicolas_upshift_promotors" /id="U2831" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.896103896103896" /psig=1 /xcortree=2447 /SigmaFactorBS="tttcgcattcatttcgaaaacaaatgaaaaattattATTTCT ATacgtaactttTATGATAAAATGATTGCTAAaaggctacgaaagcaggtggagcaat t" /listShort="ywrC, ywrB, ywrA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3586478..3586497 /Source="Nicolas_upshift_promotors" /id="U2831" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.896103896103896" /psig=1 /xcortree=2447 /SigmaFactorBS="tttcgcattcatttcgaaaacaaatgaaaaattattATTTCT ATacgtaactttTATGATAAAATGATTGCTAAaaggctacgaaagcaggtggagcaat t" /listShort="ywrC, ywrB, ywrA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3586484 /Source="Nicolas_upshifts" /id="U2831" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.896103896103896" /psig=1 /xcortree=2447 /SigmaFactorBS="tttcgcattcatttcgaaaacaaatgaaaaattattATTTCT ATacgtaactttTATGATAAAATGATTGCTAAaaggctacgaaagcaggtggagcaat t" /listShort="ywrC, ywrB, ywrA" /GFF_Attribute="listLong" CDS 3586523..3586999 /gene="chrS" /locus_tag="BSU_36110" /old_locus_tag="BSU36110" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:23989926" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 23989926; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional negative regulator of chromate transport (Lrp/AsnC family)" /protein_id="NP_391492.1" /db_xref="EnsemblGenomes-Gn:BSU36110" /db_xref="EnsemblGenomes-Tr:CAB15628" /db_xref="GOA:O05217" /db_xref="InterPro:IPR000485" /db_xref="InterPro:IPR011008" /db_xref="InterPro:IPR011991" /db_xref="InterPro:IPR019887" /db_xref="InterPro:IPR019888" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG12522" /db_xref="UniProtKB/Swiss-Prot:O05217" /translation="MSHEYQIPNLVLDETDKQILTILHEEGRISYTDLGKRVDLSRVA VQARINQLIEAGVIEKFTAVINPAKIGIHVSVFFNVEVEPQFLEEVALKLEEEPAVTS LYHMTGPSKLHMHGIFTNDQEMEEFLTKRLYPLRGVVSVDCQMLIKRYKSRMGMKL*" gene 3586523..3586999 /gene="chrS" /locus_tag="BSU_36110" /old_locus_tag="BSU36110" CDS 3587013..3587606 /gene="chrB" /locus_tag="BSU_36120" /old_locus_tag="BSU36120" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:15849754, 16850406, 23989926" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15849754, 16850406, 23989926; Product type t: transporter" /codon_start=1 /transl_table=11 /product="chromate transporter subunit N" /protein_id="NP_391493.1" /db_xref="EnsemblGenomes-Gn:BSU36120" /db_xref="EnsemblGenomes-Tr:CAB15629" /db_xref="GOA:O05216" /db_xref="InterPro:IPR003370" /db_xref="SubtiList:BG12521" /db_xref="UniProtKB/Swiss-Prot:O05216" /translation="MKNHPYRDMTAAMVRTGILGFGGGPSVIPLIRHEAVNKYKWIDD DEFGEILAIANALPGPIATKMAAYLGFKLKGTLGAIVAILAHILPTCLAMVGLFAAVN VLSHSAIVAGMIGAVTPVIAVMLGIMAYEFGQKALKGFGWVTGILFFIIAFIGLQTLQ INPGLVIIIFLAYGAFHFKLKDKITNKHSKDKGMSAS*" gene 3587013..3587606 /gene="chrB" /locus_tag="BSU_36120" /old_locus_tag="BSU36120" CDS 3587603..3588139 /gene="chrA" /locus_tag="BSU_36130" /old_locus_tag="BSU36130" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:15849754, 16850406, 23989926" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15849754, 16850406, 23989926; Product type t: transporter" /codon_start=1 /transl_table=11 /product="chromate transporter subunit C" /protein_id="NP_391494.1" /db_xref="EnsemblGenomes-Gn:BSU36130" /db_xref="EnsemblGenomes-Tr:CAB15630" /db_xref="GOA:O05215" /db_xref="InterPro:IPR003370" /db_xref="SubtiList:BG12520" /db_xref="UniProtKB/Swiss-Prot:O05215" /translation="MISIYLFMAFFIANLLGYGGGPASIPLMFEEVVNRYSWLSNDQF SNMLALANALPGPIATKIAAYVGYSAGGWPGFLIALIATVVPSALALIVLLRIIQRFR QSPVIKGMTLSVQPVIAVMMLILTWQIGADGIKAIGWVQSIVITGISLLAMTKFKMHP AFLIIAAFLYGGLVIPYL*" gene 3587603..3588139 /gene="chrA" /locus_tag="BSU_36130" /old_locus_tag="BSU36130" downshifts 3588120 /Source="Nicolas_upshifts" /id="D1869" /incds=0 /nref=4 /ntot=90 /MaxReadThrough="0.0513700000000004" /MaxDrop="3.46649" /score="29.5508265" /energy="-8.6" /TU="NA" /idTUdmin="U2829" /TUdmin=28 /isTUend="FALSE" CDS complement(3588166..3588387) /gene="ywqO" /locus_tag="BSU_36140" /old_locus_tag="BSU36140" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_391495.1" /db_xref="EnsemblGenomes-Gn:BSU36140" /db_xref="EnsemblGenomes-Tr:CAB15631" /db_xref="SubtiList:BG12519" /db_xref="UniProtKB/Swiss-Prot:P96727" /translation="MKFLLSVIAGLLILALYLFWKVQPPVWIQVETNSSQLKQSVRMA GTTLQVKHMIKSDAGEETAVISNGISGLK*" gene complement(3588166..3588387) /gene="ywqO" /locus_tag="BSU_36140" /old_locus_tag="BSU36140" upshifts 3588334 /Source="Nicolas_upshifts" /id="U2832" /multdbtbs="-" /comp="M21" /sig="Sig-" /pcomp="0.297702297702298" /psig="0.447552447552448" /xcortree=1475 /SigmaFactorBS="cttcaactgggacgaattggtttcaacttgtatccaaacagg aggctggaccttccaaaataaatagAGtgcaagaatcagcaagccagcaatgaccgac a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" misc_feature 3588341..3588342 /Source="Nicolas_upshift_promotors" /id="U2832" /multdbtbs="-" /comp="M21" /sig="Sig-" /pcomp="0.297702297702298" /psig="0.447552447552448" /xcortree=1475 /SigmaFactorBS="cttcaactgggacgaattggtttcaacttgtatccaaacagg aggctggaccttccaaaataaatagAGtgcaagaatcagcaagccagcaatgaccgac a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" CDS complement(3588384..3588929) /gene="ywqN" /locus_tag="BSU_36150" /old_locus_tag="BSU36150" /EC_number="1.-.-.-" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative oxidoreductase" /protein_id="NP_391496.1" /db_xref="EnsemblGenomes-Gn:BSU36150" /db_xref="EnsemblGenomes-Tr:CAB15632" /db_xref="GOA:P96726" /db_xref="InterPro:IPR005025" /db_xref="InterPro:IPR029039" /db_xref="PDB:1RLI" /db_xref="SubtiList:BG12518" /db_xref="UniProtKB/Swiss-Prot:P96726" /translation="MKIAVINGGTRSGGNTDVLAEKAVQGFDAEHIYLQKYPIQPIED LRHAQGGFRPVQDDYDSIIERILQCHILIFATPIYWFGMSGTLKLFIDRWSQTLRDPR FPDFKQQMSVKQAYVIAVGGDNPKIKGLPLIQQFEHIFHFMGMSFKGYVLGEGNRPGD ILRDHQALSAASRLLKRSDAI*" gene complement(3588384..3588929) /gene="ywqN" /locus_tag="BSU_36150" /old_locus_tag="BSU36150" promotor_-35 3588946..3588953 /Source="Nicolas_upshift_promotors" /id="U2833" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.756243756243756" /psig="0.996003996003996" /xcortree=1866 /SigmaFactorBS="aataaccgcaattttcatgatgcatctgctccttTGTTTACG aatgattttcttcaTCATATAATGGATTCATCAAtcaatacagatgattatttcgatt a" /listShort="ywqM" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3588968..3588987 /Source="Nicolas_upshift_promotors" /id="U2833" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.756243756243756" /psig="0.996003996003996" /xcortree=1866 /SigmaFactorBS="aataaccgcaattttcatgatgcatctgctccttTGTTTACG aatgattttcttcaTCATATAATGGATTCATCAAtcaatacagatgattatttcgatt a" /listShort="ywqM" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3588972 /Source="Nicolas_upshifts" /id="U2833" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.756243756243756" /psig="0.996003996003996" /xcortree=1866 /SigmaFactorBS="aataaccgcaattttcatgatgcatctgctccttTGTTTACG aatgattttcttcaTCATATAATGGATTCATCAAtcaatacagatgattatttcgatt a" /listShort="ywqM" /GFF_Attribute="listLong" CDS 3589052..3589933 /gene="ywqM" /locus_tag="BSU_36160" /old_locus_tag="BSU36160" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative transcriptional regulator (LysR family)" /protein_id="NP_391497.1" /db_xref="EnsemblGenomes-Gn:BSU36160" /db_xref="EnsemblGenomes-Tr:CAB15633" /db_xref="GOA:P96725" /db_xref="InterPro:IPR000847" /db_xref="InterPro:IPR005119" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG12517" /db_xref="UniProtKB/Swiss-Prot:P96725" /translation="MELKQLITFITAAEHVNFTLTAKMLNYAQSSVTSQIKSLEEEIG TPLFERLGKRLILTEAGKTFKSYAQKIIALTEEAKMATNQVRETTGTLKIGATESQCT YRLPPIIKEFKQAFPQVKLIFKPYISNEQAKEQLLQGQLDITFILDVNRMEDALHVES LIQDEIKMVAANDHPFPADLPVTLKDLQNETLLLTEDGCSYRTLFENNLHDSGIYPNK LEFVSIEAIKQCVMAGLGIGILPEMTVKDDIAAGRMKELNWQSDCPVFTQLAWHKDKW MSAPLKAFIDLTRKTFK*" gene 3589052..3589933 /gene="ywqM" /locus_tag="BSU_36160" /old_locus_tag="BSU36160" CDS complement(3590018..3590734) /gene="nfi" /locus_tag="BSU_36170" /old_locus_tag="BSU36170" /EC_number="3.1.21.7" /function="16.6: Maintain" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:1692969, 22056936, 27530626" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1692969, 22056936, 27530626; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="endonuclease V" /protein_id="NP_391498.2" /db_xref="EnsemblGenomes-Gn:BSU36170" /db_xref="EnsemblGenomes-Tr:CAB15634" /db_xref="GOA:P96724" /db_xref="InterPro:IPR007581" /db_xref="PDB:3GA2" /db_xref="SubtiList:BG12516" /db_xref="UniProtKB/Swiss-Prot:P96724" /translation="MKVFDVHKFDMKKEQDFLQVQFNLKNRINLSPTIHPDSINTCAG VDLAYWEQDGEPYGVCCIIVIDADTKEVIEKVHSMGRISVPYVSGFLAFRELPLIIEA AKKLETEPDVFLFDGNGYLHYNHMGVATHAAFFLGKPTIGIAKTYLKIKGCDFVTPEI EVGAYTDIIIDGEVYGRALRTRRDVKPIFLSCGNYIDLDSSYQITMSLINQESRLPIP VRLADLETHVLRTFYQKNHV*" gene complement(3590018..3590734) /gene="nfi" /locus_tag="BSU_36170" /old_locus_tag="BSU36170" downshifts complement(3590038) /Source="Nicolas_upshifts" /id="D1870" /incds=0 /nref=44 /ntot=216 /MaxReadThrough="1.91774" /MaxDrop="3.62442" /score="12.1019223" /energy="-7.4" /TU="NA" /idTUdmin="U2834" /TUdmin=0 /isTUend="TRUE" CDS complement(3590744..3591208) /gene="rttO" /locus_tag="BSU_36180" /old_locus_tag="BSU36180" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 22200572; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative ribonuclease antitoxin" /protein_id="NP_391499.1" /db_xref="EnsemblGenomes-Gn:BSU36180" /db_xref="EnsemblGenomes-Tr:CAB15635" /db_xref="InterPro:IPR011652" /db_xref="SubtiList:BG12515" /db_xref="UniProtKB/Swiss-Prot:P96723" /translation="MENEYDMKSIKEKGVDFEDLWFSSVSDEILDNPEDENGQPFTGL AYELYPNGQIIYFTKYKNGLAHGLTCEFYENGNKKSEKEYRYGQLHGISIIWFENGRK KSEQQYEHSILISEKNWDEEGNLLNKYEIDTDSPHFEILESRRETHINLGRE*" gene complement(3590744..3591208) /gene="rttO" /locus_tag="BSU_36180" /old_locus_tag="BSU36180" CDS complement(3591198..3593006) /gene="rttN" /locus_tag="BSU_36190" /old_locus_tag="BSU36190" /EC_number="3.1.-.-" /function="15.8: Toxin production and resistance" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 22200572; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative ribonuclease toxin" /protein_id="NP_391500.1" /db_xref="EnsemblGenomes-Gn:BSU36190" /db_xref="EnsemblGenomes-Tr:CAB15636" /db_xref="GOA:P96722" /db_xref="InterPro:IPR006829" /db_xref="InterPro:IPR025968" /db_xref="InterPro:IPR027797" /db_xref="SubtiList:BG12514" /db_xref="UniProtKB/Swiss-Prot:P96722" /translation="MSKVFESKSLIEEAKSRKKQYETLEEQLNTLKKAFQGVADLGDN FKGNGADNIKDFFQGQAEIVDSWLTLVSAQIAFLNGISGDIKDQELNDSYVETSFLDH ELPNGDLKASEIVSAHKEEIDSILSGISDIIDLDMYTLDDYADKMGDAQKIRRDTITA VDKLDESLTTEYQNLESLDNAVLTKYSVLMQATSNGKSASPMYYDKKAFHSNEVYKSV IEVENQGTTYIDAKTQQAEARRLQEKAEEEANKPWYEKTWDGVCNFTGEVTGYYDYKR ATEGVDPVTGEKLSTAERVTAGAMAAAGFIPVVGWAGRAFKGGKAIYKTGKAAIAAEH ALDAYKTGKSLDILKMTEMGAYGLVASNGFSEAVTGRDMFGNKVSEEKRKQGALEAIT IIGGAGLAHYFDRLYQKNAPYVNKVSNESLISNIAKTTEEKQTRLQYLRNKHGVLSKE DLHHRINLRAEVLNELSRIKSSGLTKKQRGPAVAGVLDKKTGNYYFGINNIDGKPPKV LHPLIHDRIVNMPTELKEGYIKTSGAGSHAEVNALNEALLQRPDADLKDLMVYVVSAR KINKKMPEGVPMPRCPHCEYITQNTNYIPEALKYGK*" gene complement(3591198..3593006) /gene="rttN" /locus_tag="BSU_36190" /old_locus_tag="BSU36190" CDS complement(3593025..3593285) /gene="ywqI" /locus_tag="BSU_36200" /old_locus_tag="BSU36200" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_391501.1" /db_xref="EnsemblGenomes-Gn:BSU36200" /db_xref="EnsemblGenomes-Tr:CAB15637" /db_xref="InterPro:IPR020299" /db_xref="SubtiList:BG12513" /db_xref="UniProtKB/Swiss-Prot:P96721" /translation="MSEIKLKYDTVIKTLDSVKDALADVSIGAAGSNGKNSLDYTKKY HEREENIKTMLGDYKKAVQKNIEDTKDNVDSLKEQDEAIAVK*" gene complement(3593025..3593285) /gene="ywqI" /locus_tag="BSU_36200" /old_locus_tag="BSU36200" CDS complement(3593295..3593717) /gene="ywqH" /locus_tag="BSU_36210" /old_locus_tag="BSU36210" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 15101989" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_391502.1" /db_xref="EnsemblGenomes-Gn:BSU36210" /db_xref="EnsemblGenomes-Tr:CAB15638" /db_xref="InterPro:IPR020326" /db_xref="InterPro:IPR031681" /db_xref="SubtiList:BG12512" /db_xref="UniProtKB/Swiss-Prot:P96720" /translation="MGYESMLADIKSSLNGKISDVEDKIEKLKKAKKDIDTLQEEAIT EIKEIVKPELGKHWTGTKADDFDKGREEAKSEASKIVNDKYNEYMASINGKIFDLEWD KAKYASELFIANGAADLLKKGEEFAEEVGNTISKLKWW*" gene complement(3593295..3593717) /gene="ywqH" /locus_tag="BSU_36210" /old_locus_tag="BSU36210" S_feature complement(3593718..3593800) /Source="Nicolas_S_feature" /locus_tag="new_3728120_3728202_c" /HighExp="T2.30H, T4.0H, T5.0H, T3.0H, T3.30H, T1.30H, T2.0H, S4, T-0.40H, S2" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.996" /TUlongSig="NA" /TUlongPSig="NA" /label="S1391" promotor_-10 complement(3593792..3593811) /Source="Nicolas_upshift_promotors" /id="U2834" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.486513486513487" /psig="0.996003996003996" /xcortree=2973 /SigmaFactorBS="gttatatgcctaaattaagccatttacccTATTTAAGccgcc ttctggcTATTTTAAAATATAATATATggaaataaagtatggaaaagtctatcttcat c" /listShort="S1391, ywqH, ywqI, ywqJ, ywqK, ywqL" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3593800) /Source="Nicolas_upshifts" /id="U2834" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.486513486513487" /psig="0.996003996003996" /xcortree=2973 /SigmaFactorBS="gttatatgcctaaattaagccatttacccTATTTAAGccgcc ttctggcTATTTTAAAATATAATATATggaaataaagtatggaaaagtctatcttcat c" /listShort="S1391, ywqH, ywqI, ywqJ, ywqK, ywqL" /GFF_Attribute="listLong" promotor_-35 complement(3593824..3593831) /Source="Nicolas_upshift_promotors" /id="U2834" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.486513486513487" /psig="0.996003996003996" /xcortree=2973 /SigmaFactorBS="gttatatgcctaaattaagccatttacccTATTTAAGccgcc ttctggcTATTTTAAAATATAATATATggaaataaagtatggaaaagtctatcttcat c" /listShort="S1391, ywqH, ywqI, ywqJ, ywqK, ywqL" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3593934..3594059) /locus_tag="BSU_36215" /old_locus_tag="BSU36215" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_009514006.1" /translation="MTKSDMADQMKNINMNNKLSAERGRSTTSASFKCLYNYDIR*" gene complement(3593934..3594059) /locus_tag="BSU_36215" /old_locus_tag="BSU36215" S_feature complement(3593977..3594108) /Source="Nicolas_S_feature" /locus_tag="new_3728379_3728510_c" /HighExp="HiOs, BI, M9-tran, T-2.40H, MG 150, Sw, M9-exp, S1, T-3.40H, T-4.40H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.19133600000000001" /TUshortSig="SigA" /TUshortPSig="0.998" /TUlongSig="NA" /TUlongPSig="NA" /label="S1392" downshifts complement(3594020) /Source="Nicolas_upshifts" /id="D1871" /incds=0 /nref=29 /ntot=208 /MaxReadThrough="3.03928" /MaxDrop="3.47153" /score="16.9931891" /energy="-8.4" /TU="NA" /idTUdmin="U2835" /TUdmin=0 /isTUend="TRUE" CDS complement(3594109..3594894) /gene="ywqG" /locus_tag="BSU_36220" /old_locus_tag="BSU36220" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_391503.1" /db_xref="EnsemblGenomes-Gn:BSU36220" /db_xref="EnsemblGenomes-Tr:CAB15639" /db_xref="InterPro:IPR015315" /db_xref="InterPro:IPR035948" /db_xref="PDB:1PV5" /db_xref="SubtiList:BG12511" /db_xref="UniProtKB/Swiss-Prot:P96719" /translation="MNHLPEKMRPYRDLLEKSAKEYVKLNVRKGKTGRYDSKIAGDPY FPKHETYPTDENGQPMKLLAQINFSHIPQLDGYPSSGILQFYISVHDDVYGLNFDDRC EQKNFRVIYFENIVENDDELVSDFSFIGTGECDFPILSEAAVEPVKSSEWVLPTDFQF EQYTGMETMEFFGQFGEDEEDIYNELAENGFGHKIGGYASFTQHDPREYAYKEHTIML LQIDSDDDIDSMWGDVGIANFFITPEDLRKKDFSNVLYNWDCS*" gene complement(3594109..3594894) /gene="ywqG" /locus_tag="BSU_36220" /old_locus_tag="BSU36220" S_feature complement(3594895..3595010) /Source="Nicolas_S_feature" /locus_tag="new_3729297_3729412_c" /HighExp="HiOs, T-1.40H, T-2.40H, T-3.40H, M9-tran, MG 150, SMM, GM 150, T0.0H, T-1.10H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.998" /TUlongSig="NA" /TUlongPSig="NA" /label="S1393" promotor_-10 complement(3595003..3595022) /Source="Nicolas_upshift_promotors" /id="U2835" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.528471528471528" /psig="0.998001998001998" /xcortree=3015 /SigmaFactorBS="tggttgcgcaccagtctttttttcatcTATTGCGGggtgctg aatacaTTTGCTACTATTTAACTATTgtttggaaaattatgcagaagtagggcttctt t" /listShort="S1393, ywqG, S1392" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3595010) /Source="Nicolas_upshifts" /id="U2835" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.528471528471528" /psig="0.998001998001998" /xcortree=3015 /SigmaFactorBS="tggttgcgcaccagtctttttttcatcTATTGCGGggtgctg aatacaTTTGCTACTATTTAACTATTgtttggaaaattatgcagaagtagggcttctt t" /listShort="S1393, ywqG, S1392" /GFF_Attribute="listLong" promotor_-35 complement(3595036..3595043) /Source="Nicolas_upshift_promotors" /id="U2835" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.528471528471528" /psig="0.998001998001998" /xcortree=3015 /SigmaFactorBS="tggttgcgcaccagtctttttttcatcTATTGCGGggtgctg aatacaTTTGCTACTATTTAACTATTgtttggaaaattatgcagaagtagggcttctt t" /listShort="S1393, ywqG, S1392" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3595086..3596408) /gene="uglF" /locus_tag="BSU_36230" /old_locus_tag="BSU36230" /EC_number="1.1.1.22" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:12970183, 15741737, 15866923, 16415592" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12970183, 15741737, 15866923, 16415592; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="UDP-glucose dehydrogenase" /protein_id="NP_391504.1" /db_xref="EnsemblGenomes-Gn:BSU36230" /db_xref="EnsemblGenomes-Tr:CAB15640" /db_xref="GOA:P96718" /db_xref="InterPro:IPR001732" /db_xref="InterPro:IPR008927" /db_xref="InterPro:IPR014026" /db_xref="InterPro:IPR014027" /db_xref="InterPro:IPR017476" /db_xref="InterPro:IPR021157" /db_xref="InterPro:IPR028357" /db_xref="InterPro:IPR036220" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG12510" /db_xref="UniProtKB/Swiss-Prot:P96718" /translation="MNITVIGTGYVGLVTGVSLSEIGHHVTCIDIDAHKIDEMRKGIS PIFEPGLEELMRKNTADGRLNFETSYEKGLAQADIIFIAVGTPQKSDGHANLEQITDA AKRIAKHVKRDTVVVTKSTVPVGTNDLINGLITEHLAEPVSISVASNPEFLREGSAIY DTFHGDRIVIGTADEKTANTLEELFRPFQIPIYQTDIRSAEMIKYASNAFLATKISFI NEISNICEKVGADIEAVAYGMGQDKRIGSQFLKAGIGYGGSCFPKDTNALVQIAGNVE HDFELLKSVIKVNNNQQAMLVDKALNRLGGVTGKTIALLGLSFKPNTDDMREAPSIVI ADRLAALDARIRAYDPIAVSHAKHVLPQAVEYKETIEEAVKGSDAVMILTDWADIKQF PLAAYQDLMETPLIFDGRNCYTLDEALAAGVEYYSVGRKAVVPSGAIQ*" gene complement(3595086..3596408) /gene="uglF" /locus_tag="BSU_36230" /old_locus_tag="BSU36230" downshifts complement(3595098) /Source="Nicolas_upshifts" /id="D1872" /incds=0 /nref=137 /ntot=221 /MaxReadThrough="3.29767" /MaxDrop="6.20721" /score="16.9931891" /energy="-8.4" /TU="NA" /idTUdmin="U2836" /TUdmin=0 /isTUend="TRUE" upshifts complement(3596442) /Source="Nicolas_upshifts" /id="U2836" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1018 /SigmaFactorBS="ggctatgcgggagatcattCGCATTcatgataggatgttcTC ATACGATATTACGGAAGctgcaaagcagcaatttaactgttggagggaaacaatgaat a" /listShort="ywqF" /GFF_Attribute="listLong" S_feature complement(3596444..3596569) /Source="Nicolas_S_feature" /locus_tag="new_3730846_3730971_c" /HighExp="dia15, H2O2, Diami, dia5, LBGstat, Paraq, LBGexp, G180, G150, G135" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.13453899999999999" /TUshortSig="SigA" /TUshortPSig="0.993" /TUlongSig="NA" /TUlongPSig="NA" /label="S1394" promotor_-10 complement(3596444..3596462) /Source="Nicolas_upshift_promotors" /id="U2836" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1018 /SigmaFactorBS="ggctatgcgggagatcattCGCATTcatgataggatgttcTC ATACGATATTACGGAAGctgcaaagcagcaatttaactgttggagggaaacaatgaat a" /listShort="ywqF" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 complement(3596478..3596483) /Source="Nicolas_upshift_promotors" /id="U2836" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1018 /SigmaFactorBS="ggctatgcgggagatcattCGCATTcatgataggatgttcTC ATACGATATTACGGAAGctgcaaagcagcaatttaactgttggagggaaacaatgaat a" /listShort="ywqF" /GFF_Attribute="listLong" /label="promotor_-35" misc_feature complement(3596549..3596568) /Source="Nicolas_upshift_promotors" /id="U2837" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.817182817182817" /psig="0.993006993006993" /xcortree=1828 /SigmaFactorBS="agaagaaaattgtttggttttttttaacagccgattctcatt tcaccactttctttttgagAGCGATATAATAGTGTATTGtatggttgaatcacatttc a" /listShort="S1394, ywqF" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(3596569) /Source="Nicolas_upshifts" /id="U2837" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.817182817182817" /psig="0.993006993006993" /xcortree=1828 /SigmaFactorBS="agaagaaaattgtttggttttttttaacagccgattctcatt tcaccactttctttttgagAGCGATATAATAGTGTATTGtatggttgaatcacatttc a" /listShort="S1394, ywqF" /GFF_Attribute="listLong" CDS complement(3596603..3597367) /gene="ptpZ" /locus_tag="BSU_36240" /old_locus_tag="BSU36240" /EC_number="3.1.3.48" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:15866923, 16415592, 16549871, 21605684, 27148221" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15866923, 16415592, 16549871, 21605684, 27148221; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="protein tyrosine-phosphatase" /protein_id="NP_391505.1" /db_xref="EnsemblGenomes-Gn:BSU36240" /db_xref="EnsemblGenomes-Tr:CAB15641" /db_xref="GOA:P96717" /db_xref="InterPro:IPR016195" /db_xref="InterPro:IPR016667" /db_xref="PDB:3QY6" /db_xref="PDB:3QY7" /db_xref="SubtiList:BG12509" /db_xref="UniProtKB/Swiss-Prot:P96717" /translation="MIDIHCHILPAMDDGAGDSADSIEMARAAVRQGIRTIIATPHHN NGVYKNEPAAVREAADQLNKRLIKEDIPLHVLPGQEIRIYGEVEQDLAKRQLLSLNDT KYILIEFPFDHVPRYAEQLFYDLQLKGYIPVIAHPERNREIRENPSLLYHLVEKGAAS QITSGSLAGIFGKQLKAFSLRLVEANLIHFVASDAHNVKTRNFHTQEALYVLEKEFGS ELPYMLTENAELLLRNQTIFRQPPQPVKRRKLFGFF*" gene complement(3596603..3597367) /gene="ptpZ" /locus_tag="BSU_36240" /old_locus_tag="BSU36240" downshifts complement(3597386) /Source="Nicolas_upshifts" /id="D1873" /incds=0 /nref=4 /ntot=152 /MaxReadThrough="3.17433" /MaxDrop="3.31415" /score="15.8630799" /energy="-9.3" /TU="U2838" /idTUdmin="U2838" /TUdmin="-330" /isTUend="FALSE" CDS complement(3597420..3598133) /gene="ptkA" /locus_tag="BSU_36250" /old_locus_tag="BSU36250" /EC_number="2.7.10.2" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:12970183, 15741737, 16415592, 16549871, 17367396, 20497499, 20815827, 23939619, 24493247, 26283769, 27148221" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12970183, 15741737, 16415592, 16549871, 17367396, 20497499, 20815827, 23939619, 24493247, 26283769, 27148221; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="maintenance protein tyrosine kinase involved in biofilm formation" /protein_id="NP_391506.1" /db_xref="EnsemblGenomes-Gn:BSU36250" /db_xref="EnsemblGenomes-Tr:CAB15642" /db_xref="GOA:P96716" /db_xref="InterPro:IPR005702" /db_xref="InterPro:IPR025669" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG12508" /db_xref="UniProtKB/Swiss-Prot:P96716" /translation="MALRKNRGSRMQRNVIAMTEPKSLNSEQYRTIRTNIEFASVDRQ MKSVMITSACPGEGKSTTAANLAVVFAQQGKKVLLIDADLRKPTVHTAFFLENTVGLT SVLLKKSSMEQAVQASNEKHLDVLTSGPIPPNPAELLSSKWMKELAYEACAAYDMVIF DTPPILAVADAQILGNVADGSVLVISSGKTEKEQAAKAKEALATCKSKLLGAIMNGKK LSKHSEYGYYGTKDNFMQK*" gene complement(3597420..3598133) /gene="ptkA" /locus_tag="BSU_36250" /old_locus_tag="BSU36250" downshifts complement(3597437) /Source="Nicolas_upshifts" /id="D1874" /incds=0 /nref=10 /ntot=157 /MaxReadThrough="4.4352" /MaxDrop="4.08842" /score="15.8630799" /energy="-9.3" /TU="U2838" /idTUdmin="U2838" /TUdmin="-381" /isTUend="FALSE" CDS complement(3598123..3598869) /gene="tkmA" /locus_tag="BSU_36260" /old_locus_tag="BSU36260" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:12970183, 23939619, 24493247, 26283769" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12970183, 23939619, 24493247, 26283769; Product type r: regulator" /codon_start=1 /transl_table=11 /product="modulator of PtkA protein tyrosine kinase activity; modulation of biofilm formation" /protein_id="NP_391507.1" /db_xref="EnsemblGenomes-Gn:BSU36260" /db_xref="EnsemblGenomes-Tr:CAB15643" /db_xref="GOA:P96715" /db_xref="InterPro:IPR003856" /db_xref="InterPro:IPR032807" /db_xref="SubtiList:BG12507" /db_xref="UniProtKB/Swiss-Prot:P96715" /translation="MGESTSLKEILSTLTKRILLIMIVTAAATAAGGLISFFALTPIY ENSTQILVNQSKNERKEVQFNDVQTNLQLINTYNVIIKSPAILDEVIKEMGLSMTSQE LNDKITVSSEQDSQVVNISVRDENAETAAHIANTIASVFQDKITSIMNVDNVSILSKA EVSEHPSPVSPKPLLNIAIAFAAGLAGSIGLAFLLEHLDNTIKSEEQLESLLDIPVLG TVSTIANEQKTAKTLQGFQSEKTGSGHFGA*" gene complement(3598123..3598869) /gene="tkmA" /locus_tag="BSU_36260" /old_locus_tag="BSU36260" promotor_-10 complement(3598901..3598920) /Source="Nicolas_upshift_promotors" /id="U2838" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.513486513486514" /psig=1 /xcortree=2281 /SigmaFactorBS="gtaaaaaaatgtcgaattatgtcacgtgaaaagCTGGagaaa tgcggtttcaaCGTTGTATAATCGTAGATGGaaaaggatgttataagagatttggagg t" /listShort="ywqC, ptkA, ywqE" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3598913) /Source="Nicolas_upshifts" /id="U2838" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.513486513486514" /psig=1 /xcortree=2281 /SigmaFactorBS="gtaaaaaaatgtcgaattatgtcacgtgaaaagCTGGagaaa tgcggtttcaaCGTTGTATAATCGTAGATGGaaaaggatgttataagagatttggagg t" /listShort="ywqC, ptkA, ywqE" /GFF_Attribute="listLong" promotor_-35 complement(3598937..3598940) /Source="Nicolas_upshift_promotors" /id="U2838" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.513486513486514" /psig=1 /xcortree=2281 /SigmaFactorBS="gtaaaaaaatgtcgaattatgtcacgtgaaaagCTGGagaaa tgcggtttcaaCGTTGTATAATCGTAGATGGaaaaggatgttataagagatttggagg t" /listShort="ywqC, ptkA, ywqE" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3599103..3599246) /gene="ywzD" /locus_tag="BSU_36269" /old_locus_tag="BSU36269" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 20709900" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="YP_003097792.1" /db_xref="EnsemblGenomes-Gn:BSU36269" /db_xref="EnsemblGenomes-Tr:CAX52703" /db_xref="UniProtKB/Swiss-Prot:C0H3S3" /translation="MSEKKLNQEEFLKILMHAHEIGEQSSEMTTKEMLENLISHIKNG YAT*" gene complement(3599103..3599246) /gene="ywzD" /locus_tag="BSU_36269" /old_locus_tag="BSU36269" downshifts complement(3599124) /Source="Nicolas_upshifts" /id="D1875" /incds=0 /nref=221 /ntot=264 /MaxReadThrough="2.76798" /MaxDrop="8.13076" /score="15.8630799" /energy="-9.3" /TU="U2839" /idTUdmin="U2841" /TUdmin=0 /isTUend="TRUE" S_feature complement(3599247..3599332) /Source="Nicolas_S_feature" /locus_tag="new_3733649_3733734_c" /HighExp="S6, S8, S7, MG-0.2, S5, M9-stat, MG-0.1, MG 25, T0.30H, BT" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="Sig-, SigD, SigK" /TUshortPSig="0.275, 1, 0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S1395" misc_feature complement(3599322..3599333) /Source="Nicolas_upshift_promotors" /id="U2839" /multdbtbs="-" /comp="M21" /sig="Sig-" /pcomp="0.290709290709291" /psig="0.274725274725275" /xcortree=1473 /SigmaFactorBS="caacacatcggccttaaaaagtttttcctaaaaaaggacata aaaaataggatgtgtcgAATGATGTATTAgagattgcaaattgataaccagcatcata t" /listShort="S1395, ywzD" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(3599332) /Source="Nicolas_upshifts" /id="U2839" /multdbtbs="-" /comp="M21" /sig="Sig-" /pcomp="0.290709290709291" /psig="0.274725274725275" /xcortree=1473 /SigmaFactorBS="caacacatcggccttaaaaagtttttcctaaaaaaggacata aaaaataggatgtgtcgAATGATGTATTAgagattgcaaattgataaccagcatcata t" /listShort="S1395, ywzD" /GFF_Attribute="listLong" S_feature complement(3599334..3599564) /Source="Nicolas_S_feature" /locus_tag="new_3733736_3733966_c" /HighExp="S6, S8, S7, S5, BT, Cold, LBGstat, LPhT, Pyr, C30" /AntisenseName="ywqB" /AntisenseCor="3.4267833233812203E-2" /AntisenseRegPval="-0.2" /CDS_PredictionProba="NA" /TUshortSig="SigD, SigK" /TUshortPSig="1, 0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S1396" promotor_-35 3599371..3599375 /Source="Nicolas_upshift_promotors" /id="U2840" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.798201798201798" /psig=1 /xcortree=2581 /SigmaFactorBS="atcctattttttatgtccttttttaggaaaaACTTTttaagg ccgatgtgtTGCGATATAATAGAGAAATTggatctttttattacgtgactcggttagg a" /listShort="ywqB, ywqA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3599391..3599410 /Source="Nicolas_upshift_promotors" /id="U2840" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.798201798201798" /psig=1 /xcortree=2581 /SigmaFactorBS="atcctattttttatgtccttttttaggaaaaACTTTttaagg ccgatgtgtTGCGATATAATAGAGAAATTggatctttttattacgtgactcggttagg a" /listShort="ywqB, ywqA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3599400 /Source="Nicolas_upshifts" /id="U2840" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.798201798201798" /psig=1 /xcortree=2581 /SigmaFactorBS="atcctattttttatgtccttttttaggaaaaACTTTttaagg ccgatgtgtTGCGATATAATAGAGAAATTggatctttttattacgtgactcggttagg a" /listShort="ywqB, ywqA" /GFF_Attribute="listLong" CDS 3599450..3601060 /gene="ywqB" /locus_tag="BSU_36270" /old_locus_tag="BSU36270" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 22720735; Product type f: factor" /codon_start=1 /transl_table=11 /product="putative replication initiation protein" /protein_id="NP_391508.2" /db_xref="EnsemblGenomes-Gn:BSU36270" /db_xref="EnsemblGenomes-Tr:CAB15644" /db_xref="GOA:P96714" /db_xref="InterPro:IPR007527" /db_xref="SubtiList:BG12506" /db_xref="UniProtKB/Swiss-Prot:P96714" /translation="MLQNMISKDDVLASAEQLKELLPYNEENVQLIKKALILYRQDSV YRLQAVSPTEVTAYVQDVVPVRVTLNLFVIVKSGCSCPSGRICRHMLAVFLYVYAMFE RVGTFTEYWLEREKLEESKELVRRQFQEKVLPNEESLSSWLAFFDSEFSLWQARTPEG SQNMQGLYYGYLSALKKHAPNKPELKSLYQIHSAIAVWLRMFTLIEAGKLNPEQDFYS LNPYVEQLMDTIYSSIDKLKTYALSFALDPFLDKTPDVIRHLLLKEEIFQYERIRVFG EIWSALLSRPKWVAREQEILKKEAGRRFSPELQFGRLHLEFLQKNDDVIFEEADQFPP EALPYTFQWLSEMTAKKDWKRLKTWYQQIEPIAMGYTKLDKPFKEIRDVIGELFLLLN AYVQQTNDQALFERFAAGCLPYTFTEYSHHLYEKKRYAEWIEIHSLVGFSINEMDKMM LKEIAASDPEALIPAYHREVAFFIDQKNRSSYKEAARYLKKLRTLYKKAKKQKVWERY IQLLSSHYKRLRALQEELQKGKLIDGES*" gene 3599450..3601060 /gene="ywqB" /locus_tag="BSU_36270" /old_locus_tag="BSU36270" promotor_-10 complement(3599552..3599570) /Source="Nicolas_upshift_promotors" /id="U2841" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2784 /SigmaFactorBS="cgtaagccgtaacttccgtcggactcactgcttGTAAACGAt agactgaatcctGCCGATATAAAATAAGGGCttttttgatcagctgaacattttcctc a" /listShort="S1396, S1395, ywzD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3599564) /Source="Nicolas_upshifts" /id="U2841" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2784 /SigmaFactorBS="cgtaagccgtaacttccgtcggactcactgcttGTAAACGAt agactgaatcctGCCGATATAAAATAAGGGCttttttgatcagctgaacattttcctc a" /listShort="S1396, S1395, ywzD" /GFF_Attribute="listLong" S_feature complement(3599566..3599740) /Source="Nicolas_S_feature" /locus_tag="new_3733968_3734142_c" /HighExp="S6, S8, S7, S5, BT, B36, G/S, Pyr, B60, C30" /AntisenseName="ywqB" /AntisenseCor="-0.10880748846525" /AntisenseRegPval="-1.1000000000000001" /CDS_PredictionProba="NA" /TUshortSig="SigK" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S1397" promotor_-35 complement(3599584..3599591) /Source="Nicolas_upshift_promotors" /id="U2841" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2784 /SigmaFactorBS="cgtaagccgtaacttccgtcggactcactgcttGTAAACGAt agactgaatcctGCCGATATAAAATAAGGGCttttttgatcagctgaacattttcctc a" /listShort="S1396, S1395, ywzD" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(3599727..3599746) /Source="Nicolas_upshift_promotors" /id="U2842" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1319 /SigmaFactorBS="aagcttttccctctccagccaatactctgtaaAAGTACCCAc tcgctcgaacatTGCATATACATATAAAAACAcagccagcatatggcggcagattctt c" /listShort="S1397, S1396, S1395, ywzD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3599740) /Source="Nicolas_upshifts" /id="U2842" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1319 /SigmaFactorBS="aagcttttccctctccagccaatactctgtaaAAGTACCCAc tcgctcgaacatTGCATATACATATAAAAACAcagccagcatatggcggcagattctt c" /listShort="S1397, S1396, S1395, ywzD" /GFF_Attribute="listLong" promotor_-35 complement(3599760..3599768) /Source="Nicolas_upshift_promotors" /id="U2842" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1319 /SigmaFactorBS="aagcttttccctctccagccaatactctgtaaAAGTACCCAc tcgctcgaacatTGCATATACATATAAAAACAcagccagcatatggcggcagattctt c" /listShort="S1397, S1396, S1395, ywzD" /GFF_Attribute="listLong" /label="promotor_-35" CDS 3601047..3603815 /gene="hepA" /locus_tag="BSU_36280" /old_locus_tag="BSU36280" /function="16.9: Replicate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 9507009, 9614128, 11751638, 17913745, 19282450; Product type f: factor" /codon_start=1 /transl_table=11 /product="ATPase involved in RNA remodelling DNA recombination and repair" /protein_id="NP_391509.1" /db_xref="EnsemblGenomes-Gn:BSU36280" /db_xref="EnsemblGenomes-Tr:CAB15645" /db_xref="GOA:P94593" /db_xref="InterPro:IPR000330" /db_xref="InterPro:IPR001650" /db_xref="InterPro:IPR014001" /db_xref="InterPro:IPR022138" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG12505" /db_xref="UniProtKB/Swiss-Prot:P94593" /translation="MASLKEILIHVEQMEDGSFTLSAFDENEQPLPYSHMKKHLFQWH ESSFYGTFLEDVSFIGTTAVLLSPWMTVELLGKNSFNSFSSVQLTEETEPLIEAASTI YEFIADGDFMPDYDAWTNGVFRWKDRDNILEGFTAEWFSAAVQDYIQYDDDLREKWEH IKEKSPAVTTFRGHFLDEEDFLEGIGWIDDQSPFTVGLRLNEPDFDGDEWKIEMFLRD KKSGAVEFFDGLKSLKKSWQAYSDKIAREQDRFHRTVPWLSFDSGTTLISEEEAWIFL SEASETLVDMGVEILLPSWWQIVRDSNMMLKAKVSSSPRGESFVGMNALLDFNWRFAT NGIELTEAEFNELVASNRRLVNIRGQWVKIDPQFIKQMKRLMEKAESEGLHMSDILAR ELMDQQDGGLEDSDLIDTSAFAGIQFDLSKQLRSLIRKLTAAENLPEHKVSPSFKGTL RPYQKYGMNWLLFLRESGFGACLADDMGLGKTIQMIAYFLHVKESGRQKTPHLIIAPT SVLGNWQRELQTFAPDLSVALHYGPRRPKGDDFAAHYENADVVLTSYGLSHADTEELS SVTWNTICLDEAQNIKNAHTKQSRAIRKLKGLHHIALSGTPMENRLTELWSIFDFMNK GYLGSLTGFHKRYVLPIEKDRDEKRIGQLQQLIRPFLLRRTKRDEEVALNLPEKLEEK EFIPLSAEQASLYEQLVKDTFDHMTSLTGMQRKALILSMLGRLKQICDHPALYLKEEQ TELLAGRSVKLEKLLELMTAIRAQNESCLIFTQYIQMGNMMKRLLEKTFGEPVQFLNG SLSKQERDTLVEKFQRKEYPTLILSLKAGGTGLNLTAANHVIHYDRWWNPAVENQATD RAYRIGQERFVHVHKMITTGTIEEKIDVMLESKQTLNDQIIQSENWITELSTQELEEL FTLSATAQ*" gene 3601047..3603815 /gene="hepA" /locus_tag="BSU_36280" /old_locus_tag="BSU36280" downshifts complement(3603864) /Source="Nicolas_upshifts" /id="D1876" /incds=0 /nref=9 /ntot=202 /MaxReadThrough="1.80101" /MaxDrop="4.14573" /score="30.708119" /energy="-14.4" /TU="U2843" /idTUdmin="U2844" /TUdmin=12 /isTUend="TRUE" CDS complement(3603941..3604798) /gene="ywpJ" /locus_tag="BSU_36290" /old_locus_tag="BSU36290" /EC_number="3.1.3.-" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2b: Function from indirect experimental evidences (e.g. phenotypes); PubMedId: 25848029; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="phosphatase of unidentified specificity (possibly promiscuous)" /protein_id="NP_391510.1" /db_xref="EnsemblGenomes-Gn:BSU36290" /db_xref="EnsemblGenomes-Tr:CAB15646" /db_xref="GOA:P94592" /db_xref="InterPro:IPR000150" /db_xref="InterPro:IPR006379" /db_xref="InterPro:IPR023214" /db_xref="InterPro:IPR036412" /db_xref="PDB:1NRW" /db_xref="SubtiList:BG12504" /db_xref="UniProtKB/Swiss-Prot:P94592" /translation="MKLIAIDLDGTLLNSKHQVSLENENALRQAQRDGIEVVVSTGRA HFDVMSIFEPLGIKTWVISANGAVIHDPEGRLYHHETIDKKRAYDILSWLESENYYYE VFTGSAIYTPQNGRELLDVELDRFRSANPEADLSVLKQAAEVQYSQSGFAYINSFQEL FEADEPIDFYNILGFSFFKEKLEAGWKRYEHAEDLTLVSSAEHNFELSSRKASKGQAL KRLAKQLNIPLEETAAVGDSLNDKSMLEAAGKGVAMGNAREDIKSIADAVTLTNDEHG VAHMMKHLL*" gene complement(3603941..3604798) /gene="ywpJ" /locus_tag="BSU_36290" /old_locus_tag="BSU36290" CDS complement(3604804..3605580) /gene="glcR" /locus_tag="BSU_36300" /old_locus_tag="BSU36300" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:11491085" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11491085; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator (glucose repression ofcatabolic operons)" /protein_id="NP_391511.1" /db_xref="EnsemblGenomes-Gn:BSU36300" /db_xref="EnsemblGenomes-Tr:CAB15647" /db_xref="GOA:P94591" /db_xref="InterPro:IPR001034" /db_xref="InterPro:IPR014036" /db_xref="InterPro:IPR018356" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG12503" /db_xref="UniProtKB/Swiss-Prot:P94591" /translation="MYQEERLVAILDFLKQHNRITTEQICTLLQVSRDTARRDLVKLE EQNAIIRTRGGAILPTVHQKIQSYSGRLKTVSEEKNKIGRLAASLIHDGDRVILDAST TVQACAKHLNAVDCTVITNSINLADVLSDKEGIEIYLLGGKLEKEHRFLYGSSVIEKL SSYHVDKALIGVVGISEHGITIAHEEDGMVKRKMIQQAKQVIALADHSKLGSTSFYQY AELNEIDLLITDRLPNQAFCDLLDRNGVELLVTEQDEGKD*" gene complement(3604804..3605580) /gene="glcR" /locus_tag="BSU_36300" /old_locus_tag="BSU36300" promotor_-10 complement(3605606..3605625) /Source="Nicolas_upshift_promotors" /id="U2843" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.963036963036963" /psig=1 /xcortree=3012 /SigmaFactorBS="ttggttctctcgacgcatttttacttaaaatcacttattaaT GTTGAATaaaatcaaataaaaACTTATAATTACTTATAAATgattgctgagaaaagga a" /listShort="glcR, ywpJ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3605628) /Source="Nicolas_upshifts" /id="U2843" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.963036963036963" /psig=1 /xcortree=3012 /SigmaFactorBS="ttggttctctcgacgcatttttacttaaaatcacttattaaT GTTGAATaaaatcaaataaaaACTTATAATTACTTATAAATgattgctgagaaaagga a" /listShort="glcR, ywpJ" /GFF_Attribute="listLong" S_feature complement(3605630..3605702) /Source="Nicolas_S_feature" /locus_tag="new_3740032_3740104_c" /HighExp="C30, GM 150, T-4.40H, G/S, C90, S2, T-5.40H, T-3.40H, T-2.40H, S0" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="SigA" /TUlongPSig=1 /label="S1398" promotor_-35 complement(3605640..3605647) /Source="Nicolas_upshift_promotors" /id="U2843" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.963036963036963" /psig=1 /xcortree=3012 /SigmaFactorBS="ttggttctctcgacgcatttttacttaaaatcacttattaaT GTTGAATaaaatcaaataaaaACTTATAATTACTTATAAATgattgctgagaaaagga a" /listShort="glcR, ywpJ" /GFF_Attribute="listLong" /label="promotor_-35" S_feature complement(3605704..3605803) /Source="Nicolas_S_feature" /locus_tag="new_3740106_3740205_c" /HighExp="HiOs, S2, T-3.40H, T0.30H, C90, G/S, T1.0H, T0.0H, Pyr, T-1.40H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="1, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S1399" downshifts complement(3605747) /Source="Nicolas_upshifts" /id="D1877" /incds=0 /nref=221 /ntot=258 /MaxReadThrough="3.81096" /MaxDrop="7.17295" /score="-7.00620083" /energy="-7.5" /TU="U2844" /idTUdmin="U2846" /TUdmin="-1" /isTUend="TRUE" CDS complement(3605804..3606145) /gene="ssbB" /locus_tag="BSU_36310" /old_locus_tag="BSU36310" /function="16.11: Scavenge (Catabolism)" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:14762004, 16009133, 16549871, 17630974, 25138221" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 14762004, 16009133, 16549871, 17630974, 25138221; Product type f: factor" /codon_start=1 /transl_table=11 /product="single-strand DNA-binding protein" /protein_id="NP_391512.2" /db_xref="EnsemblGenomes-Gn:BSU36310" /db_xref="EnsemblGenomes-Tr:CAB15648" /db_xref="GOA:C0SPB6" /db_xref="InterPro:IPR000424" /db_xref="InterPro:IPR011344" /db_xref="InterPro:IPR012340" /db_xref="PDB:3VDY" /db_xref="SubtiList:BG12502" /db_xref="UniProtKB/Swiss-Prot:C0SPB6" /translation="MFNQVMLVGRLTKDPDLRYTSAGAAVAHVTLAVNRSFKNASGEI EADYVNCTLWRKTAENTALYCQKGSLVGVSGRIQTRSYENEEGVNVYVTEVLADTVRF MDPKPREKAAD*" gene complement(3605804..3606145) /gene="ssbB" /locus_tag="BSU_36310" /old_locus_tag="BSU36310" promotor_-10 complement(3606167..3606186) /Source="Nicolas_upshift_promotors" /id="U2844" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.89010989010989" /psig=1 /xcortree=2964 /SigmaFactorBS="aacgaaagataaaaacagaggctgaaagccatttttaagCGT TTTTCttttcttgttgcaTCATTTACAATACATACAACcgcaaggagaggaggaatcg c" /listShort="ssbB, S1399, S1398, glcR, ywpJ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3606186) /Source="Nicolas_upshifts" /id="U2844" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.89010989010989" /psig=1 /xcortree=2964 /SigmaFactorBS="aacgaaagataaaaacagaggctgaaagccatttttaagCGT TTTTCttttcttgttgcaTCATTTACAATACATACAACcgcaaggagaggaggaatcg c" /listShort="ssbB, S1399, S1398, glcR, ywpJ" /GFF_Attribute="listLong" promotor_-35 complement(3606200..3606207) /Source="Nicolas_upshift_promotors" /id="U2844" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.89010989010989" /psig=1 /xcortree=2964 /SigmaFactorBS="aacgaaagataaaaacagaggctgaaagccatttttaagCGT TTTTCttttcttgttgcaTCATTTACAATACATACAACcgcaaggagaggaggaatcg c" /listShort="ssbB, S1399, S1398, glcR, ywpJ" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3606222..3606605) /gene="ywpG" /locus_tag="BSU_36320" /old_locus_tag="BSU36320" /experiment="publication(s) with functional evidences, PMID:23060960" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 23060960; Product type f: factor" /codon_start=1 /transl_table=11 /product="interaction partner of DynA" /protein_id="NP_391513.1" /db_xref="EnsemblGenomes-Gn:BSU36320" /db_xref="EnsemblGenomes-Tr:CAB15649" /db_xref="SubtiList:BG12501" /db_xref="UniProtKB/Swiss-Prot:P94589" /translation="MNQFRLKEIYIDGVPSESHLIQKEVTYMLSRKEVFEVHLNKKGR ISFLYETQDGMEQYKIKLSMPEKKLSFQWFAWDGSSYVRMNTQNWLTKQIFFRFLKST YFFKGKKQKMFLAEGKMKTKDKNRG*" gene complement(3606222..3606605) /gene="ywpG" /locus_tag="BSU_36320" /old_locus_tag="BSU36320" promotor_-10 complement(3606627..3606646) /Source="Nicolas_upshift_promotors" /id="U2846" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.977022977022977" /psig=1 /xcortree=2300 /SigmaFactorBS="cctgcaatgttggggctaaagaattttgtatgagcgaaaCAT TTAATaatttctattttttCATTATACTGTAACTGACTAtggattacggagagatgtg g" /listShort="ywpG, ssbB, S1399" /listLong="S1398, glcR, ywpJ" /label="promotor_-10" misc_feature 3606634..3606653 /Source="Nicolas_upshift_promotors" /id="U2845" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.502497502497502" /psig="0.973026973026973" /xcortree=3123 /SigmaFactorBS="aaatttcttttaaacgaaattgattcataccacatctctccg taatccatagtcagTTACAGTATAATGAAAAAATagaaattattaaatgtttcgctca t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 3606638 /Source="Nicolas_upshifts" /id="U2845" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.502497502497502" /psig="0.973026973026973" /xcortree=3123 /SigmaFactorBS="aaatttcttttaaacgaaattgattcataccacatctctccg taatccatagtcagTTACAGTATAATGAAAAAATagaaattattaaatgtttcgctca t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" upshifts complement(3606647) /Source="Nicolas_upshifts" /id="U2846" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.977022977022977" /psig=1 /xcortree=2300 /SigmaFactorBS="cctgcaatgttggggctaaagaattttgtatgagcgaaaCAT TTAATaatttctattttttCATTATACTGTAACTGACTAtggattacggagagatgtg g" /listShort="ywpG, ssbB, S1399" /listLong="S1398, glcR, ywpJ" promotor_-35 complement(3606661..3606668) /Source="Nicolas_upshift_promotors" /id="U2846" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.977022977022977" /psig=1 /xcortree=2300 /SigmaFactorBS="cctgcaatgttggggctaaagaattttgtatgagcgaaaCAT TTAATaatttctattttttCATTATACTGTAACTGACTAtggattacggagagatgtg g" /listShort="ywpG, ssbB, S1399" /listLong="S1398, glcR, ywpJ" /label="promotor_-35" misc_feature 3606728..3606747 /Source="Nicolas_upshift_promotors" /id="U2847" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.818181818181818" /psig=1 /xcortree=1915 /SigmaFactorBS="tcgctcatacaaaattctttagccccaacattgcaggatttt ttcctcgaaaacgttTATGTTATAATGGAAGGCAAgaaaactttggaagtaatcgggg t" /listShort="ywpF" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 3606731 /Source="Nicolas_upshifts" /id="U2847" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.818181818181818" /psig=1 /xcortree=1915 /SigmaFactorBS="tcgctcatacaaaattctttagccccaacattgcaggatttt ttcctcgaaaacgttTATGTTATAATGGAAGGCAAgaaaactttggaagtaatcgggg t" /listShort="ywpF" /GFF_Attribute="listLong" downshifts complement(3606780) /Source="Nicolas_upshifts" /id="D1878" /incds=0 /nref=2 /ntot=169 /MaxReadThrough="0.85282" /MaxDrop="4.02798" /score="27.231517" /energy="-14" /TU="NA" /idTUdmin="U2846" /TUdmin="-1034" /isTUend="FALSE" CDS 3606780..3607190 /gene="ywpF" /locus_tag="BSU_36330" /old_locus_tag="BSU36330" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 25663006" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_391514.1" /db_xref="EnsemblGenomes-Gn:BSU36330" /db_xref="EnsemblGenomes-Tr:CAB15650" /db_xref="InterPro:IPR025573" /db_xref="SubtiList:BG12500" /db_xref="UniProtKB/Swiss-Prot:P94588" /translation="MKTFKLVDLNVERVDKEEQSIEQFPLIDGLIINKEDGENHWLIE ALVQKEHLSFFEQLQNSQSEAKVFVTITKKSNRPAQLTAAVKNIVKLEESIQVLLYGQ MVTRKQQGTETILESLVKEGYTGTKLIEAFKQKL*" gene 3606780..3607190 /gene="ywpF" /locus_tag="BSU_36330" /old_locus_tag="BSU36330" S_feature 3607191..3607274 /Source="Nicolas_S_feature" /locus_tag="new_3741593_3741676" /HighExp="BC, LBGtran, T3.30H, Etha, T2.0H, Lbtran, M9-stat, T3.0H, dia5, LBGstat" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="NA" /TUshortPSig="NA" /TUlongSig="NA" /TUlongPSig="NA" /label="S1400" downshifts 3607232 /Source="Nicolas_upshifts" /id="D1879" /incds=0 /nref=214 /ntot=260 /MaxReadThrough="1.83981" /MaxDrop="6.19197" /score="18.4023831" /energy="-14" /TU="NA" /idTUdmin="U2847" /TUdmin=0 /isTUend="TRUE" CDS complement(3607330..3607638) /gene="ywpE" /locus_tag="BSU_36340" /old_locus_tag="BSU36340" /function="16.13: Shape" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15187182, 21800427, 21906378; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative sortase" /protein_id="NP_391515.1" /db_xref="EnsemblGenomes-Gn:BSU36340" /db_xref="EnsemblGenomes-Tr:CAB15651" /db_xref="GOA:P94587" /db_xref="InterPro:IPR005754" /db_xref="InterPro:IPR023365" /db_xref="SubtiList:BG12499" /db_xref="UniProtKB/Swiss-Prot:P94587" /translation="MRRDQKMGEGNYPLAGHHLKQKNLLFGPLENIKTGAQIVITDFK KDYIYSVTSKDIISEMDADVVEETNKKEITLITCDKAVKTEGRLVVKGELVDSFGHTN *" gene complement(3607330..3607638) /gene="ywpE" /locus_tag="BSU_36340" /old_locus_tag="BSU36340" downshifts complement(3607331) /Source="Nicolas_upshifts" /id="D1880" /incds=0 /nref=1 /ntot=36 /MaxReadThrough="0.11027" /MaxDrop="2.8132" /score="27.231517" /energy="-14" /TU="NA" /idTUdmin="U2849" /TUdmin=1540 /isTUend="FALSE" CDS 3607982..3608818 /gene="ywpD" /locus_tag="BSU_36350" /old_locus_tag="BSU36350" /function="16.12: Sense" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 16740923; Product type rc: receptor" /codon_start=1 /transl_table=11 /product="putative two-component sensor histidine kinase" /protein_id="NP_391516.1" /db_xref="EnsemblGenomes-Gn:BSU36350" /db_xref="EnsemblGenomes-Tr:CAB15652" /db_xref="GOA:P94586" /db_xref="InterPro:IPR001789" /db_xref="InterPro:IPR003594" /db_xref="InterPro:IPR010559" /db_xref="InterPro:IPR011006" /db_xref="InterPro:IPR036890" /db_xref="SubtiList:BG12498" /db_xref="UniProtKB/Swiss-Prot:P94586" /translation="MKIRERFSMVDLPVLIITAAIIGHDKYKAFHAGANDILQKPYHY SEFMARIQNLIMMKHTANQATRMEMAFLQSQIKPHFLYNVLNTIISLTHLDIEKAREV TEEFTNYLRMSFDFQNTSAISSFRHELSIINSYLSIEKTRFSNRLEVLFDIDEDIDFI LPPLMIQPLVENAVLHGVSKKRGGGWIKLTAKKQSKNEYHIKVEDNGPGITPEKQIDL LSTDFDRSVGLKNINQRLKHFCGSELMISSTPDAGTSVSMLIHLAETTGSPKELKDTE RT*" gene 3607982..3608818 /gene="ywpD" /locus_tag="BSU_36350" /old_locus_tag="BSU36350" promotor_-35 3608198..3608205 /Source="Nicolas_upshift_promotors" /id="U2848" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.81918081918082" /psig="0.993006993006993" /xcortree=642 /SigmaFactorBS="caaatcaagccacaagaatggaaatggcgtttctcCAGTCGC AaatcaagcctcattTTCTTTATAATGTATTAAACacgattatttctctcactcattt g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3608220..3608239 /Source="Nicolas_upshift_promotors" /id="U2848" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.81918081918082" /psig="0.993006993006993" /xcortree=642 /SigmaFactorBS="caaatcaagccacaagaatggaaatggcgtttctcCAGTCGC AaatcaagcctcattTTCTTTATAATGTATTAAACacgattatttctctcactcattt g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3608223 /Source="Nicolas_upshifts" /id="U2848" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.81918081918082" /psig="0.993006993006993" /xcortree=642 /SigmaFactorBS="caaatcaagccacaagaatggaaatggcgtttctcCAGTCGC AaatcaagcctcattTTCTTTATAATGTATTAAACacgattatttctctcactcattt g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" downshifts 3608817 /Source="Nicolas_upshifts" /id="D1881" /incds=0 /nref=13 /ntot=132 /MaxReadThrough="0.11837" /MaxDrop="3.37937" /score="9.16906941" /energy="-8.6" /TU="NA" /idTUdmin="U2848" /TUdmin=154 /isTUend="FALSE" CDS complement(3608865..3609257) /gene="mscL" /locus_tag="BSU_36360" /old_locus_tag="BSU36360" /function="16.1: Circulate" /function="16.8: Protect" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:12948773, 15063854, 15165739, 16897034, 22685134, 22720735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12948773, 15063854, 15165739, 16897034, 22685134, 22720735; Product type t : transporter" /codon_start=1 /transl_table=11 /product="large conductance mechanosensitive channel protein" /protein_id="NP_391517.1" /db_xref="EnsemblGenomes-Gn:BSU36360" /db_xref="EnsemblGenomes-Tr:CAB15653" /db_xref="GOA:P94585" /db_xref="InterPro:IPR001185" /db_xref="InterPro:IPR019823" /db_xref="InterPro:IPR036019" /db_xref="SubtiList:BG12497" /db_xref="UniProtKB/Swiss-Prot:P94585" /translation="MWNEFKAFAMRGNIVDLAIGVVIGGAFGKIVTSLVNDIIMPLVG LLLGGLDFSGLSFTFGDAVVKYGSFIQTIVNFLIISFSIFIVIRTLNGLRRKKEAEEE AAEEAVDAQEELLKEIRDLLKQQAKSPE*" gene complement(3608865..3609257) /gene="mscL" /locus_tag="BSU_36360" /old_locus_tag="BSU36360" downshifts complement(3608871) /Source="Nicolas_upshifts" /id="D1882" /incds=0 /nref=216 /ntot=255 /MaxReadThrough="2.23487" /MaxDrop="6.5103" /score="28.9904077" /energy="-11.4" /TU="NA" /idTUdmin="U2849" /TUdmin=0 /isTUend="TRUE" CDS complement(3609330..3609755) /gene="fabZ" /locus_tag="BSU_36370" /old_locus_tag="BSU36370" /EC_number="4.2.1.59" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 8910376, 12682299, 15194690, 15371447, 18093984, 22580319, 23322253, 27874013; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="beta-hydroxyacyl-[acyl carrier protein] dehydratase" /protein_id="NP_391518.2" /db_xref="EnsemblGenomes-Gn:BSU36370" /db_xref="EnsemblGenomes-Tr:CAB15654" /db_xref="GOA:P94584" /db_xref="InterPro:IPR010084" /db_xref="InterPro:IPR013114" /db_xref="InterPro:IPR029069" /db_xref="SubtiList:BG12496" /db_xref="UniProtKB/Swiss-Prot:P94584" /translation="MLDTQQIKEIIPHRYPFLLVDRITEVEEGKRAKGYKNVTANEEF FNGHFPQYPVMPGVLIVEALAQVGAVAMLIKEENRGRLAFFAGIDNCRFKKQVKPGDQ LHLEVEIIRARGTIGRGKGVATVDGEVVCEVELTFALGE*" gene complement(3609330..3609755) /gene="fabZ" /locus_tag="BSU_36370" /old_locus_tag="BSU36370" promotor_-10 complement(3609816..3609835) /Source="Nicolas_upshift_promotors" /id="U2849" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.865134865134865" /psig=1 /xcortree=2557 /SigmaFactorBS="acggctctcattgacagttggttacattttagcgcGGTTGAA AaagagattaattcaTAATATACTTTTCAAATGTAcagattggatctttgatgattgc t" /listShort="fabZ, mscL" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3609832) /Source="Nicolas_upshifts" /id="U2849" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.865134865134865" /psig=1 /xcortree=2557 /SigmaFactorBS="acggctctcattgacagttggttacattttagcgcGGTTGAA AaagagattaattcaTAATATACTTTTCAAATGTAcagattggatctttgatgattgc t" /listShort="fabZ, mscL" /GFF_Attribute="listLong" S_feature complement(3609834..3609918) /Source="Nicolas_S_feature" /locus_tag="new_3744236_3744320_c" /HighExp="Diami, dia5, Cold, dia15, H2O2, C30, Etha, Oxctl, Paraq, M/G" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.995" /TUlongSig="SigD, SigA" /TUlongPSig="0.999, 0.837" /label="S1401" promotor_-35 complement(3609850..3609857) /Source="Nicolas_upshift_promotors" /id="U2849" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.865134865134865" /psig=1 /xcortree=2557 /SigmaFactorBS="acggctctcattgacagttggttacattttagcgcGGTTGAA AaagagattaattcaTAATATACTTTTCAAATGTAcagattggatctttgatgattgc t" /listShort="fabZ, mscL" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 3609897 /Source="Nicolas_upshifts" /id="U2850" /multdbtbs="SigA,SigX" /comp="M4" /sig="SigA" /pcomp="0.956043956043956" /psig="0.988011988011988" /xcortree=3190 /SigmaFactorBS="gaattaatctctttttcaaccgcgctaaaatgtaaccaactg tcaatgagagccgtcaaaagtTATGATATGATAATTATAGAttttaccaatagcaaag a" /listShort="rapD, S1403" /GFF_Attribute="listLong" misc_feature 3609900..3609919 /Source="Nicolas_upshift_promotors" /id="U2850" /multdbtbs="SigA,SigX" /comp="M4" /sig="SigA" /pcomp="0.956043956043956" /psig="0.988011988011988" /xcortree=3190 /SigmaFactorBS="gaattaatctctttttcaaccgcgctaaaatgtaaccaactg tcaatgagagccgtcaaaagtTATGATATGATAATTATAGAttttaccaatagcaaag a" /listShort="rapD, S1403" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" promotor_-10 complement(3609910..3609929) /Source="Nicolas_upshift_promotors" /id="U2851" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.417582417582418" /psig="0.995004995004995" /xcortree=1970 /SigmaFactorBS="agcattcttttttcaataaacttcgaaatcATTTTCctacct ctttgctATTGGTAAAATCTATAATTAtcatatcataacttttgacggctctcattga c" /listShort="S1401" /listLong="fabZ, mscL" /label="promotor_-10" upshifts complement(3609918) /Source="Nicolas_upshifts" /id="U2851" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.417582417582418" /psig="0.995004995004995" /xcortree=1970 /SigmaFactorBS="agcattcttttttcaataaacttcgaaatcATTTTCctacct ctttgctATTGGTAAAATCTATAATTAtcatatcataacttttgacggctctcattga c" /listShort="S1401" /listLong="fabZ, mscL" S_feature complement(3609920..3611004) /Source="Nicolas_S_feature" /locus_tag="new_3744322_3745406_c" /HighExp="Cold, C30, Lbstat, Glucon, Glu, Paraq, Pyr, H2O2, Fru, C90" /AntisenseName="rapD" /AntisenseCor="5.8390464430913601E-3" /AntisenseRegPval=0 /CDS_PredictionProba="NA" /TUshortSig="SigD" /TUshortPSig="0.999" /TUlongSig="SigA" /TUlongPSig="0.837" /label="S1402" promotor_-35 complement(3609943..3609948) /Source="Nicolas_upshift_promotors" /id="U2851" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.417582417582418" /psig="0.995004995004995" /xcortree=1970 /SigmaFactorBS="agcattcttttttcaataaacttcgaaatcATTTTCctacct ctttgctATTGGTAAAATCTATAATTAtcatatcataacttttgacggctctcattga c" /listShort="S1401" /listLong="fabZ, mscL" /label="promotor_-35" CDS 3609947..3611011 /gene="rapD" /locus_tag="BSU_36380" /old_locus_tag="BSU36380" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:17227471" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 17227471; Product type r: regulator" /codon_start=1 /transl_table=11 /product="response regulator aspartate phosphatase" /protein_id="NP_391519.1" /db_xref="EnsemblGenomes-Gn:BSU36380" /db_xref="EnsemblGenomes-Tr:CAB15655" /db_xref="GOA:P94583" /db_xref="InterPro:IPR011990" /db_xref="InterPro:IPR013026" /db_xref="InterPro:IPR019734" /db_xref="SubtiList:BG11967" /db_xref="UniProtKB/Swiss-Prot:P94583" /translation="MISKFIEKRMLNMLDEWYSAMSKRKMNHVCTLKEKIDQHLPKIK KNTKLWMRYQLFQARHQLLFENQNGLDSLFDGLYGLEDKMDDELKYYLYFFSGLYEMV KTAPKHAVHHFKKAEQYLAAIHNTFEAADLYYQTAGAYYLMKSPPLSVQYVKKALHIY LHQFGYIKKVITCKLLLAVNYIDQERYEKAEQLFKEIIKKTQQLHDENLLCHAYYNLG FLKATEKKDQEALLYFRKVLKNQEFEMNSPVSYLHCVYESVRALFKTGNITEAKAVLQ KGKELSEKVDIQTIYLKLKTLEALYTSAEDPYEQLLEYVLELEKIEAWVDLEVLLEDI TEYYKKKDDFEKAAFFIMRG*" gene 3609947..3611011 /gene="rapD" /locus_tag="BSU_36380" /old_locus_tag="BSU36380" S_feature 3611012..3611896 /Source="Nicolas_S_feature" /locus_tag="new_3745414_3746298" /HighExp="M9-stat, T4.0H, T2.0H, T3.30H, T2.30H, T3.0H, T1.30H, T5.0H, T1.0H, T0.30H" /AntisenseName="flhP" /AntisenseCor="-0.32116112580252298" /AntisenseRegPval="-7.1" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.988" /TUlongSig="NA" /TUlongPSig="NA" /label="S1403" CDS complement(3611034..3611843) /gene="flhP" /locus_tag="BSU_36390" /old_locus_tag="BSU36390" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:22730131" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 22730131; Product type s: structure" /codon_start=1 /transl_table=11 /product="flagellar hook-basal body accessory protein" /protein_id="NP_391520.2" /db_xref="EnsemblGenomes-Gn:BSU36390" /db_xref="EnsemblGenomes-Tr:CAB15656" /db_xref="GOA:P39753" /db_xref="InterPro:IPR001444" /db_xref="InterPro:IPR010930" /db_xref="InterPro:IPR019776" /db_xref="InterPro:IPR020013" /db_xref="SubtiList:BG10918" /db_xref="UniProtKB/Swiss-Prot:P39753" /translation="MLRSMLTASTTLNQLQQQIDTISSNLSNSNTTGYKAKDTNFSEL VRQQFDQVDEKNEEVAKARKTPPGLRLGVGAMMSSRLVSDQGSIQKTDRDLDIAFTSP YQYLQVNVNGNRQYTRDGALYVTPSAANANQLQLVTGNGYPVLDENGNTVNIDSSMKN ITINKNGTLTASDGNAVQRFNLGVVQVNNPQELKSEGNNLFSIDNAAAFEELNGANRQ NIGMQQGSLEMSNVDISEQMTDLITSQRSYQLNSRTITMGDQMLGLINSVR*" gene complement(3611034..3611843) /gene="flhP" /locus_tag="BSU_36390" /old_locus_tag="BSU36390" downshifts complement(3611049) /Source="Nicolas_upshifts" /id="D1883" /incds=0 /nref=174 /ntot=256 /MaxReadThrough="4.65461" /MaxDrop="5.56507" /score="8.59904552" /energy="-7.4" /TU="U2853" /idTUdmin="U2854" /TUdmin=1 /isTUend="TRUE" CDS complement(3611877..3612689) /gene="flhO" /locus_tag="BSU_36400" /old_locus_tag="BSU36400" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:1905667, 16621824, 22730131" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1905667, 16621824, 22730131; Product type s: structure" /codon_start=1 /transl_table=11 /product="flagellar basal-body accessory rod protein" /protein_id="NP_391521.1" /db_xref="EnsemblGenomes-Gn:BSU36400" /db_xref="EnsemblGenomes-Tr:CAB15657" /db_xref="GOA:P39752" /db_xref="InterPro:IPR001444" /db_xref="InterPro:IPR010930" /db_xref="InterPro:IPR019776" /db_xref="SubtiList:BG10917" /db_xref="UniProtKB/Swiss-Prot:P39752" /translation="MLKGLYTATSAMIAQQRRTEMLSNNIANANTSGYKADQGSMRAF PEMLLSRIESKSPAGTSRTEIGSVNTGVYMQELKPLFTQGSLKSTDQPTDIALIENQV PMSAETNEKAALFYPVQTADGIRYSKSSTFSLNENNQLTINGRPILSTDRQPITVDNE NFTVSENGTVTTNGRTAGQIDVRMAEDVRNLKRDGNDLYSTADGNDLPSAAGNNQVAY SLKQGVSELSNVDVTSAYTEMTEAYRSFEANQKVIQAYDKSMDKAANEIGKI*" gene complement(3611877..3612689) /gene="flhO" /locus_tag="BSU_36400" /old_locus_tag="BSU36400" S_feature complement(3612690..3612769) /Source="Nicolas_S_feature" /locus_tag="new_3747092_3747171_c" /HighExp="C90, Lbtran, Cold, GM-0.2, GM 15, GM 10, C30, GM 90, GM-0.1, MG 150" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigD, SigA" /TUshortPSig="0.999, 0.837" /TUlongSig="NA" /TUlongPSig="NA" /label="S1404" promotor_-35 3612720..3612727 /Source="Nicolas_upshift_promotors" /id="U2852" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.93906093906094" /psig=1 /xcortree=2095 /SigmaFactorBS="atttcccacctctaaaaatggcattttttcCAGTTGTCatat aggaacgttCGTTCTATAATAAAAACTCAgtattttatcctattatcgtcatttaaca t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3612741..3612760 /Source="Nicolas_upshift_promotors" /id="U2852" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.93906093906094" /psig=1 /xcortree=2095 /SigmaFactorBS="atttcccacctctaaaaatggcattttttcCAGTTGTCatat aggaacgttCGTTCTATAATAAAAACTCAgtattttatcctattatcgtcatttaaca t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3612750 /Source="Nicolas_upshifts" /id="U2852" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.93906093906094" /psig=1 /xcortree=2095 /SigmaFactorBS="atttcccacctctaaaaatggcattttttcCAGTTGTCatat aggaacgttCGTTCTATAATAAAAACTCAgtattttatcctattatcgtcatttaaca t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 complement(3612763..3612781) /Source="Nicolas_upshift_promotors" /id="U2853" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=2805 /SigmaFactorBS="aagaatgaggtttttttatgaaaaagcCTTCACGAaaagatg ttaaatGACGATAATAGGATAAAATactgagtttttattatagaacgaacgttcctat a" /listShort="S1404, flhO, flhP, S1402" /listLong="S1401, fabZ, mscL" /label="promotor_-10" upshifts complement(3612769) /Source="Nicolas_upshifts" /id="U2853" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=2805 /SigmaFactorBS="aagaatgaggtttttttatgaaaaagcCTTCACGAaaagatg ttaaatGACGATAATAGGATAAAATactgagtttttattatagaacgaacgttcctat a" /listShort="S1404, flhO, flhP, S1402" /listLong="S1401, fabZ, mscL" promotor_-35 complement(3612795..3612802) /Source="Nicolas_upshift_promotors" /id="U2853" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=2805 /SigmaFactorBS="aagaatgaggtttttttatgaaaaagcCTTCACGAaaagatg ttaaatGACGATAATAGGATAAAATactgagtttttattatagaacgaacgttcctat a" /listShort="S1404, flhO, flhP, S1402" /listLong="S1401, fabZ, mscL" /label="promotor_-35" CDS complement(3612852..3613853) /gene="mbl" /locus_tag="BSU_36410" /old_locus_tag="BSU36410" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:11290328, 12530960, 14588250, 15745453, 17064365, 19659933, 21091501, 23879732, 27215790" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11290328, 12530960, 14588250, 15745453, 17064365, 19659933, 21091501, 23879732, 27215790; Product type f: factor" /codon_start=1 /transl_table=11 /product="MreB-like morphogen" /protein_id="NP_391522.2" /db_xref="EnsemblGenomes-Gn:BSU36410" /db_xref="EnsemblGenomes-Tr:CAB15658" /db_xref="GOA:P39751" /db_xref="InterPro:IPR004753" /db_xref="SubtiList:BG10916" /db_xref="UniProtKB/Swiss-Prot:P39751" /translation="MFARDIGIDLGTANVLIHVKGKGIVLNEPSVVALDKNSGKVLAV GEEARRMVGRTPGNIVAIRPLKDGVIADFEVTEAMLKHFINKLNVKGLFSKPRMLICC PTNITSVEQKAIKEAAEKSGGKHVYLEEEPKVAAIGAGMEIFQPSGNMVVDIGGGTTD IAVISMGDIVTSSSIKMAGDKFDMEILNYIKREYKLLIGERTAEDIKIKVATVFPDAR HEEISIRGRDMVSGLPRTITVNSKEVEEALRESVAVIVQAAKQVLERTPPELSADIID RGVIITGGGALLNGLDQLLAEELKVPVLVAENPMDCVAIGTGVMLDNMDKLPKRKLS* " gene complement(3612852..3613853) /gene="mbl" /locus_tag="BSU_36410" /old_locus_tag="BSU36410" downshifts complement(3612858) /Source="Nicolas_upshifts" /id="D1884" /incds=0 /nref=108 /ntot=240 /MaxReadThrough="5.6154" /MaxDrop="4.18076" /score="20.122637" /energy="-11.2" /TU="U2854" /idTUdmin="U2855" /TUdmin="-1" /isTUend="TRUE" misc_feature complement(3613908..3613927) /Source="Nicolas_upshift_promotors" /id="U2854" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.561438561438561" /psig="0.837162837162837" /xcortree=799 /SigmaFactorBS="gttcataaaacatccgcaaaaatttgtaaagaacttattgtg cttccaactttttttctatatttTATGATAATATATATAATTAgggcacaatgtggat a" /listShort="mbl, S1404, flhO, flhP" /listLong="S1402, S1401, fabZ, mscL" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(3613932) /Source="Nicolas_upshifts" /id="U2854" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.561438561438561" /psig="0.837162837162837" /xcortree=799 /SigmaFactorBS="gttcataaaacatccgcaaaaatttgtaaagaacttattgtg cttccaactttttttctatatttTATGATAATATATATAATTAgggcacaatgtggat a" /listShort="mbl, S1404, flhO, flhP" /listLong="S1402, S1401, fabZ, mscL" S_feature complement(3613934..3614018) /Source="Nicolas_S_feature" /locus_tag="new_3748336_3748420_c" /HighExp="S5, S6, S4, S7, S8, S3, B36, T5.0H, B60, Pyr" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigEF" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1405" CDS complement(3614019..3614300) /gene="spoIIID" /locus_tag="BSU_36420" /old_locus_tag="BSU36420" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:9023218, 9324264, 15598884, 22720735, 24584501" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9023218, 9324264, 15598884, 22720735, 24584501; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator (stage III sporulation)" /protein_id="NP_391523.1" /db_xref="EnsemblGenomes-Gn:BSU36420" /db_xref="EnsemblGenomes-Tr:CAB15659" /db_xref="GOA:P15281" /db_xref="InterPro:IPR014208" /db_xref="InterPro:IPR018356" /db_xref="InterPro:IPR036388" /db_xref="PDB:2L0K" /db_xref="SubtiList:BG10408" /db_xref="UniProtKB/Swiss-Prot:P15281" /translation="MHDYIKERTIKIGKYIVETKKTVRVIAKEFGVSKSTVHKDLTER LPEINPDLANEVKEILDYHKSIRHLRGGEATKLKYKKDEILEGEPVQQS*" gene complement(3614019..3614300) /gene="spoIIID" /locus_tag="BSU_36420" /old_locus_tag="BSU36420" CDS complement(3614315..3614425) /gene="usd" /locus_tag="BSU_36430" /old_locus_tag="BSU36430" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 9023218; Product type ph: phenotype" /codon_start=1 /transl_table=11 /product="putative factor required for translation of spoIIID" /protein_id="NP_391524.1" /db_xref="EnsemblGenomes-Gn:BSU36430" /db_xref="EnsemblGenomes-Tr:CAB15660" /db_xref="SubtiList:BG11984" /db_xref="UniProtKB/Swiss-Prot:O32276" /translation="MGIFHKLTFKTIQRRSGIMNDSLQNTDLISHFSHPF*" gene complement(3614315..3614425) /gene="usd" /locus_tag="BSU_36430" /old_locus_tag="BSU36430" promotor_-10 complement(3614456..3614474) /Source="Nicolas_upshift_promotors" /id="U2855" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1092 /SigmaFactorBS="atctgaaaaagttcgtttcaccccttgtccttattgagtttt tAGCATAttcccaaaagaatgcTAATACACTGTTACAAACCtaacaaagagagtgttt g" /listShort="usd, spoIIID, S1405, mbl" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3614478) /Source="Nicolas_upshifts" /id="U2855" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1092 /SigmaFactorBS="atctgaaaaagttcgtttcaccccttgtccttattgagtttt tAGCATAttcccaaaagaatgcTAATACACTGTTACAAACCtaacaaagagagtgttt g" /listShort="usd, spoIIID, S1405, mbl" /GFF_Attribute="listLong" promotor_-35 complement(3614490..3614495) /Source="Nicolas_upshift_promotors" /id="U2855" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1092 /SigmaFactorBS="atctgaaaaagttcgtttcaccccttgtccttattgagtttt tAGCATAttcccaaaagaatgcTAATACACTGTTACAAACCtaacaaagagagtgttt g" /listShort="usd, spoIIID, S1405, mbl" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 3614571..3614577 /Source="Nicolas_upshift_promotors" /id="U2856" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.347652347652348" /psig="0.98001998001998" /xcortree=305 /SigmaFactorBS="ctatttcgcgtcactaaattttcaTCTTTACaactattgatc gcTCCTGTAAAATGAAATAAGCaattagttacttaggtaagttttttagaaggagacc g" /listShort="ywoH, ywoG" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3614591..3614610 /Source="Nicolas_upshift_promotors" /id="U2856" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.347652347652348" /psig="0.98001998001998" /xcortree=305 /SigmaFactorBS="ctatttcgcgtcactaaattttcaTCTTTACaactattgatc gcTCCTGTAAAATGAAATAAGCaattagttacttaggtaagttttttagaaggagacc g" /listShort="ywoH, ywoG" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3614607 /Source="Nicolas_upshifts" /id="U2856" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.347652347652348" /psig="0.98001998001998" /xcortree=305 /SigmaFactorBS="ctatttcgcgtcactaaattttcaTCTTTACaactattgatc gcTCCTGTAAAATGAAATAAGCaattagttacttaggtaagttttttagaaggagacc g" /listShort="ywoH, ywoG" /GFF_Attribute="listLong" CDS 3614650..3615063 /gene="ywoH" /locus_tag="BSU_36440" /old_locus_tag="BSU36440" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative transcriptional regulator (MarR family)" /protein_id="NP_391525.1" /db_xref="EnsemblGenomes-Gn:BSU36440" /db_xref="EnsemblGenomes-Tr:CAB15661" /db_xref="GOA:P94578" /db_xref="InterPro:IPR000835" /db_xref="InterPro:IPR011991" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG12495" /db_xref="UniProtKB/Swiss-Prot:P94578" /translation="MSYVNRHLIHQINQSARLIAKKANEQLEPFGLYSSQWSVLYCLR TIGPMTQKEIWSYLNVEAPTVTRTIKRLEENGWVQRRQGEDKREKLVVLTKEAEKKYE EINVKMLKFEEELLADFRDEDKEAFSHLFRMFLQQ*" gene 3614650..3615063 /gene="ywoH" /locus_tag="BSU_36440" /old_locus_tag="BSU36440" CDS 3615085..3616275 /gene="ywoG" /locus_tag="BSU_36450" /old_locus_tag="BSU36450" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative efflux transporter" /protein_id="NP_391526.1" /db_xref="EnsemblGenomes-Gn:BSU36450" /db_xref="EnsemblGenomes-Tr:CAB15662" /db_xref="GOA:P94577" /db_xref="InterPro:IPR011701" /db_xref="InterPro:IPR020846" /db_xref="InterPro:IPR036259" /db_xref="SubtiList:BG12494" /db_xref="UniProtKB/Swiss-Prot:P94577" /translation="MKKADAIWTKDFIMVLLVNLFVFVFFYTFLTVLPIYTLQELGGT ESQGGLLISLFLLSAIITRPFSGAIVERFGKKRMAIVSMALFALSSFLYMPIHNFSLL LGLRFFQGIWFSILTTVTGAIAADIIPAKRRGEGLGYFAMSMNLAMAIGPFLGLNLMR VVSFPVFFTAFALFMVAGLLVSFLIKVPQSKDSGTTVFRFAFSDMFEKGALKIATVGL FISFCYSTVTSYLSVFAKSVDLSDISGYFFVCFAVTMMIARPFTGKLFDKVGPGIVIY PSILIFSVGLCMLSFTHSGLMLLLSGAVIGLGYGSIVPCMQTLAIQKSPAHRSGFATA TFFTFFDSGIAVGSYVFGLFVASAGFSAIYLTAGLFVLIALLLYTWSQKKPAEAEGKV SIAE*" gene 3615085..3616275 /gene="ywoG" /locus_tag="BSU_36450" /old_locus_tag="BSU36450" CDS complement(3616366..3617772) /gene="ywoF" /locus_tag="BSU_36460" /old_locus_tag="BSU36460" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15266115, 16607952, 23504016; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative pectin lyase" /protein_id="NP_391527.1" /db_xref="EnsemblGenomes-Gn:BSU36460" /db_xref="EnsemblGenomes-Tr:CAB15663" /db_xref="GOA:P94576" /db_xref="InterPro:IPR006626" /db_xref="InterPro:IPR006633" /db_xref="InterPro:IPR011050" /db_xref="InterPro:IPR012334" /db_xref="SubtiList:BG12493" /db_xref="UniProtKB/Swiss-Prot:P94576" /translation="MRKWYFILLAGVLTSVILAFVYDKTKANEEGSGDYLYVSPNGSD QNEGTKEKPFRTLAHASEKAAAGTTVMIREGTYHETLDVKHSGTDGKPITFRNYENEN VVISGESVANAEYETPLIRIHDKHDIAISGLTIQDLSVSSEEATAIGIYVSGSSSHIA IKDNHIRGIKTTADEGNAHGIAVYGTGSMKDIRIEDNTVEKLTLGASEAVVLNGNIDG FTVAGNVVRNNNNIGIDLIGYEGTADKNDYVRNGVVENNTVYQNSTYGNPAYGDEYSA GGIYVDGGHDIEIKNNTVYDNDIGIEATSEHKGKYANAIQITDNKVYNNAYTGISIGG YDKKRGGTSNSLIARNIMYRNDTKGLYGGQLLLQYDTKNNTIEKNILTAGDSRLFIGN DFTENEGNTVNHNVYHKEADQDGIWMWKKKEYDSFSSYRKATKNDQQSIYADPMFRDE ASYDFSLDPDSPARPVIE*" gene complement(3616366..3617772) /gene="ywoF" /locus_tag="BSU_36460" /old_locus_tag="BSU36460" downshifts complement(3616663) /Source="Nicolas_upshifts" /id="D1885" /incds=1 /nref=1 /ntot=78 /MaxReadThrough="5.28695" /MaxDrop="2.1962" /score="4.73902293" /energy="-22.3" /TU="U2857" /idTUdmin="U2857" /TUdmin="-924" /isTUend="FALSE" promotor_-10 complement(3617805..3617824) /Source="Nicolas_upshift_promotors" /id="U2857" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.756243756243756" /psig="0.997002997002997" /xcortree=2979 /SigmaFactorBS="gaataagatctatttagacggtatattttcatatttttgaaA TGGttttccataaatagAACATTTATAATGGTTTTAGaaatctattctaaaacgaaat g" /listShort="ywoF" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3617823) /Source="Nicolas_upshifts" /id="U2857" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.756243756243756" /psig="0.997002997002997" /xcortree=2979 /SigmaFactorBS="gaataagatctatttagacggtatattttcatatttttgaaA TGGttttccataaatagAACATTTATAATGGTTTTAGaaatctattctaaaacgaaat g" /listShort="ywoF" /GFF_Attribute="listLong" promotor_-35 complement(3617839..3617842) /Source="Nicolas_upshift_promotors" /id="U2857" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.756243756243756" /psig="0.997002997002997" /xcortree=2979 /SigmaFactorBS="gaataagatctatttagacggtatattttcatatttttgaaA TGGttttccataaatagAACATTTATAATGGTTTTAGaaatctattctaaaacgaaat g" /listShort="ywoF" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3617878..3619350) /gene="pucI" /locus_tag="BSU_36470" /old_locus_tag="BSU36470" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:11344136, 12029039, 15849754, 16850406, 26967546" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11344136, 12029039, 15849754, 16850406, 26967546; Product type t : transporter" /codon_start=1 /transl_table=11 /product="allantoin permease" /protein_id="NP_391528.1" /db_xref="EnsemblGenomes-Gn:BSU36470" /db_xref="EnsemblGenomes-Tr:CAB15664" /db_xref="GOA:P94575" /db_xref="InterPro:IPR001248" /db_xref="InterPro:IPR012681" /db_xref="SubtiList:BG12492" /db_xref="UniProtKB/Swiss-Prot:P94575" /translation="MKLKESQQQSNRLSNEDLVPLGQEKRTWKAMNFASIWMGCIHNI PTYATVGGLIAIGLSPWQVLAIIITASLILFGALALNGHAGTKYGLPFPVIIRASYGI YGANIPALLRAFTAIMWLGIQTFAGSTALNILLLNMWPGWGEIGGEWNILGIHLSGLL SFVFFWAIHLLVLHHGMESIKRFEVWAGPLVYLVFGGMVWWAVDIAGGLGPIYSQPGK FHTFSETFWPFAAGVTGIIGIWATLILNIPDFTRFAETQKEQIKGQFYGLPGTFALFA FASITVTSGSQVAFGEPIWDVVDILARFDNPYVIVLSVITLCIATISVNVAANIVSPA YDIANALPKYINFKRGSFITALLALFTVPWKLMESATSVYAFLGLIGGMLGPVAGVMM ADYFIIRKRELSVDDLYSETGRYVYWKGYNYRAFAATMLGALISLIGMYVPVLKSLYD ISWFVGVLISFLFYIVLMRVHPPASLAIETVEHAQVRQAE*" gene complement(3617878..3619350) /gene="pucI" /locus_tag="BSU_36470" /old_locus_tag="BSU36470" CDS complement(3619531..3620889) /gene="ywoD" /locus_tag="BSU_36480" /old_locus_tag="BSU36480" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative efflux transporter" /protein_id="NP_391529.1" /db_xref="EnsemblGenomes-Gn:BSU36480" /db_xref="EnsemblGenomes-Tr:CAB15665" /db_xref="GOA:P94574" /db_xref="InterPro:IPR011701" /db_xref="InterPro:IPR020846" /db_xref="InterPro:IPR036259" /db_xref="SubtiList:BG12491" /db_xref="UniProtKB/Swiss-Prot:P94574" /translation="MLSKKSRAVFLTAVASGTMLNPLNSSMISLALHSIQHEFHLSFT TVSWLISSFYLASAVAQPVTGKLGDLIGRKRLFLFGLILVAVSAIGAPFAPTFMTLLV MRLFQSVGSSAIYPSGVGLIRNHIHERQASALAVLSIFASAMTALGPTAGGFLIVWGG WPAIFIVNLPFIILSFLLGLYMFPKDQKKGAGIKTIIRQLDILGIVLFAGGIIFLLSF LLSFSTSPHAVEGVLGLLLLCAFVWRELKTDKPFIDVRLFKTQRNLSAVYVQFILLNV FFYCLFFGLPSYFQDEMHLSVQTSGLFMLFMSGMSIVVSPLTGKWIDRSGVVKPIFAG ALLMTAGAVLLTIFFINVQTIGKGLILSLLGIGYGLGNVALQAAMLETSPSNMVGTTS GLFQTCRYLGSILSSVILGILFGKEITAAHFDMMGIIMIIAGGASLLMAVRFAALMKT AS*" gene complement(3619531..3620889) /gene="ywoD" /locus_tag="BSU_36480" /old_locus_tag="BSU36480" downshifts complement(3619545) /Source="Nicolas_upshifts" /id="D1886" /incds=0 /nref=58 /ntot=198 /MaxReadThrough="1.44148" /MaxDrop="4.13092" /score="20.2036192" /energy="-12.8" /TU="NA" /idTUdmin="U2858" /TUdmin=0 /isTUend="TRUE" CDS complement(3620889..3621458) /gene="ywoC" /locus_tag="BSU_36490" /old_locus_tag="BSU36490" /EC_number="3.-.-.-" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative enzyme of isochorismatase family" /protein_id="NP_391530.2" /db_xref="EnsemblGenomes-Gn:BSU36490" /db_xref="EnsemblGenomes-Tr:CAB15666" /db_xref="GOA:P94573" /db_xref="InterPro:IPR000868" /db_xref="InterPro:IPR016291" /db_xref="InterPro:IPR036380" /db_xref="SubtiList:BG12490" /db_xref="UniProtKB/Swiss-Prot:P94573" /translation="MMNTLNIDFQKTALVIIDLQKGIVPIDQSGQVVPNAKKLVDEFR KHNGFISFVNVAFHDGADALKPQTDEPAQGGSGEMPADWAEFVPEIGVQDGDYTVTKR QWGAFFGTDLDLQLRRRGIDTIVLCGIATNIGVESTAREAFQLGYQQIFITDAMSTFS DEEHEATLRFIFPRIGKSRTTEEFLEQVK*" gene complement(3620889..3621458) /gene="ywoC" /locus_tag="BSU_36490" /old_locus_tag="BSU36490" promotor_-10 complement(3621477..3621488) /Source="Nicolas_upshift_promotors" /id="U2858" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=804 /SigmaFactorBS="ccttctgagaatttcacaagcatcataaaagaacttaggcag tgtgaAGAGTAAaatatgcaatgtgAGAAACACTAACagtatcaggaggagacgtatg a" /listShort="ywoC, ywoD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3621495) /Source="Nicolas_upshifts" /id="U2858" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=804 /SigmaFactorBS="ccttctgagaatttcacaagcatcataaaagaacttaggcag tgtgaAGAGTAAaatatgcaatgtgAGAAACACTAACagtatcaggaggagacgtatg a" /listShort="ywoC, ywoD" /GFF_Attribute="listLong" promotor_-35 complement(3621502..3621508) /Source="Nicolas_upshift_promotors" /id="U2858" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=804 /SigmaFactorBS="ccttctgagaatttcacaagcatcataaaagaacttaggcag tgtgaAGAGTAAaatatgcaatgtgAGAAACACTAACagtatcaggaggagacgtatg a" /listShort="ywoC, ywoD" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3621565..3621732) /locus_tag="BSU_36499" /old_locus_tag="BSU36499" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /pseudo /codon_start=1 /transl_table=11 /product="hypothetical protein" /db_xref="PSEUDO:CCQ48605.1" /translation="MSYPALDGPPQIHGHFQAGTDRQQAGDEAMTPFMITVLAGLFVC TTCYYYIKEKS*" gene complement(3621565..3621732) /locus_tag="BSU_36499" /old_locus_tag="BSU36499" /pseudo CDS complement(3621642..3622106) /gene="ywoB" /locus_tag="BSU_36500" /old_locus_tag="BSU36500" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406, 21856850; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative integral inner membrane protein" /protein_id="NP_391531.1" /db_xref="EnsemblGenomes-Gn:BSU36500" /db_xref="EnsemblGenomes-Tr:CAB15667" /db_xref="GOA:P94572" /db_xref="InterPro:IPR020218" /db_xref="SubtiList:BG12489" /db_xref="UniProtKB/Swiss-Prot:P94572" /translation="MMNKGGRLRKAVRKSIPATFRLFLAFNFFVYGLAKVVIGQFGEV TPEIEAAAGKGFTIAWTFFGYSHVYELFIGFGEILAAVLLLIPRTAALGAVIFMPIIV NIVLINYCFDIGVQDLSTILMVMCLILLWMDRRKFMGIFRQEPIDSRQVMKR*" gene complement(3621642..3622106) /gene="ywoB" /locus_tag="BSU_36500" /old_locus_tag="BSU36500" promotor_-10 complement(3622136..3622155) /Source="Nicolas_upshift_promotors" /id="U2859" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.736263736263736" /psig="0.999000999001" /xcortree=2195 /SigmaFactorBS="actattcatatgagctgaaaagggaATTGACATtaattagaa tactCTATACTGTATTAAGTGTACtacatcaaataatacactgagggggatgtatgat g" /listShort="ywoB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3622141) /Source="Nicolas_upshifts" /id="U2859" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.736263736263736" /psig="0.999000999001" /xcortree=2195 /SigmaFactorBS="actattcatatgagctgaaaagggaATTGACATtaattagaa tactCTATACTGTATTAAGTGTACtacatcaaataatacactgagggggatgtatgat g" /listShort="ywoB" /GFF_Attribute="listLong" promotor_-35 complement(3622169..3622176) /Source="Nicolas_upshift_promotors" /id="U2859" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.736263736263736" /psig="0.999000999001" /xcortree=2195 /SigmaFactorBS="actattcatatgagctgaaaagggaATTGACATtaattagaa tactCTATACTGTATTAAGTGTACtacatcaaataatacactgagggggatgtatgat g" /listShort="ywoB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 3622307..3622310 /Source="Nicolas_upshift_promotors" /id="U2860" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.835164835164835" /psig="0.978021978021978" /xcortree=320 /SigmaFactorBS="acatttctcaaaaaccatgtcaggaaatcttacatgaaAATG ttttatcattctttTTTCTCTATAATGAAGAAATataataattgctttttattctgaa a" /listShort="amtB, glnK" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3622325..3622344 /Source="Nicolas_upshift_promotors" /id="U2860" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.835164835164835" /psig="0.978021978021978" /xcortree=320 /SigmaFactorBS="acatttctcaaaaaccatgtcaggaaatcttacatgaaAATG ttttatcattctttTTTCTCTATAATGAAGAAATataataattgctttttattctgaa a" /listShort="amtB, glnK" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3622329 /Source="Nicolas_upshifts" /id="U2860" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.835164835164835" /psig="0.978021978021978" /xcortree=320 /SigmaFactorBS="acatttctcaaaaaccatgtcaggaaatcttacatgaaAATG ttttatcattctttTTTCTCTATAATGAAGAAATataataattgctttttattctgaa a" /listShort="amtB, glnK" /GFF_Attribute="listLong" CDS 3622388..3623602 /gene="amtB" /locus_tag="BSU_36510" /old_locus_tag="BSU36510" /function="16.1: Circulate" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:14600241, 15849754, 16850406, 17001076, 21435182" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 14600241, 15849754, 16850406, 17001076, 21435182; Product type t : transporter" /codon_start=1 /transl_table=11 /product="ammonium transporter" /protein_id="NP_391532.1" /db_xref="EnsemblGenomes-Gn:BSU36510" /db_xref="EnsemblGenomes-Tr:CAB15668" /db_xref="GOA:Q07429" /db_xref="InterPro:IPR001905" /db_xref="InterPro:IPR018047" /db_xref="InterPro:IPR024041" /db_xref="InterPro:IPR029020" /db_xref="SubtiList:BG10869" /db_xref="UniProtKB/Swiss-Prot:Q07429" /translation="MQMGDTVFMFFCALLVWLMTPGLALFYGGMVKSKNVLSTAMHSF SSIAIVSIVWVLFGYTLAFAPGNSIIGGLEWAGLKGVGFDPGDYSDTIPHSLFMMFQM TFAVLTTAIISGAFAERMRFGAFLLFSVLWASLVYTPVAHWVWGGGWIGQLGALDFAG GNVVHISSGVAGLVLAIVLGKRKDGTASSPHNLIYTFLGGALIWFGWFGFNVGSALTL DGVAMYAFINTNTAAAAGIAGWILVEWIINKKPTMLGAVSGAIAGLVAITPAAGFVTP FASIIIGIIGGAVCFWGVFSLKKKFGYDDALDAFGLHGIGGTWGGIATGLFATTSVNS AGADGLFYGDASLIWKQIVAIAATYVFVFIVTFVIIKIVSLFLPLRATEEEESLGLDL TMHGEKAYQDSM*" gene 3622388..3623602 /gene="amtB" /locus_tag="BSU_36510" /old_locus_tag="BSU36510" promotor_-10 complement(3623218..3623236) /Source="Nicolas_upshift_promotors" /id="U2861" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2846 /SigmaFactorBS="taagcgagaatactccccagaaACAAACAGctccgccgatga tGCCGATAATAATGGAAGCGaacggtgtgacaaatccggcagccggcgtaatggcgac a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3623219) /Source="Nicolas_upshifts" /id="U2861" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2846 /SigmaFactorBS="taagcgagaatactccccagaaACAAACAGctccgccgatga tGCCGATAATAATGGAAGCGaacggtgtgacaaatccggcagccggcgtaatggcgac a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(3623250..3623257) /Source="Nicolas_upshift_promotors" /id="U2861" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2846 /SigmaFactorBS="taagcgagaatactccccagaaACAAACAGctccgccgatga tGCCGATAATAATGGAAGCGaacggtgtgacaaatccggcagccggcgtaatggcgac a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 3623468..3623474 /Source="Nicolas_upshift_promotors" /id="U2862" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.344655344655345" /psig="0.993006993006993" /xcortree=610 /SigmaFactorBS="tctggaaacaaatcgtcgccatcgccgccacttatgttTTTG TATttattgtcactttCGTTATTATTAAAATTGTAAgcctcttccttccccttcgcgc a" /listShort="glnK" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3623488..3623507 /Source="Nicolas_upshift_promotors" /id="U2862" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.344655344655345" /psig="0.993006993006993" /xcortree=610 /SigmaFactorBS="tctggaaacaaatcgtcgccatcgccgccacttatgttTTTG TATttattgtcactttCGTTATTATTAAAATTGTAAgcctcttccttccccttcgcgc a" /listShort="glnK" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3623490 /Source="Nicolas_upshifts" /id="U2862" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.344655344655345" /psig="0.993006993006993" /xcortree=610 /SigmaFactorBS="tctggaaacaaatcgtcgccatcgccgccacttatgttTTTG TATttattgtcactttCGTTATTATTAAAATTGTAAgcctcttccttccccttcgcgc a" /listShort="glnK" /GFF_Attribute="listLong" CDS 3623614..3623964 /gene="glnK" /locus_tag="BSU_36520" /old_locus_tag="BSU36520" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:14600241, 17001076, 21435182, 23461034, 25691471" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 14600241, 17001076, 21435182, 23461034, 25691471; Product type r: regulator" /codon_start=1 /transl_table=11 /product="nitrogen-regulated PII-like regulator protein" /protein_id="NP_391533.1" /db_xref="EnsemblGenomes-Gn:BSU36520" /db_xref="EnsemblGenomes-Tr:CAB15669" /db_xref="GOA:Q07428" /db_xref="InterPro:IPR002187" /db_xref="InterPro:IPR011322" /db_xref="InterPro:IPR015867" /db_xref="InterPro:IPR017918" /db_xref="PDB:4R25" /db_xref="PDB:4RX6" /db_xref="SubtiList:BG10870" /db_xref="UniProtKB/Swiss-Prot:Q07428" /translation="MSGQMFKVEIVTRPANFEKLKQELGKIGVTSLTFSNVHGCGLQK AHTELYRGVKIESNVYERLKIEIVVSKVPVDQVTETAKRVLKTGSPGDGKIFVYEISN TINIRTGEEGPEAL*" gene 3623614..3623964 /gene="glnK" /locus_tag="BSU_36520" /old_locus_tag="BSU36520" downshifts 3623957 /Source="Nicolas_upshifts" /id="D1887" /incds=0 /nref=179 /ntot=251 /MaxReadThrough="2.13701" /MaxDrop="8.63831" /score="25.582072" /energy="-12.5" /TU="NA" /idTUdmin="U2860" /TUdmin=0 /isTUend="TRUE" promotor_-35 3624016..3624024 /Source="Nicolas_upshift_promotors" /id="U2863" /multdbtbs="-" /comp="M2" /sig="SigI" /pcomp=1 /psig=1 /xcortree=1773 /SigmaFactorBS="actccggatctctttttttgtgcacagaatcCCCCCAGAAac cgcgattcctcTTCGAATTCtcttcaagcgccgttatttcagacaatctctattttta t" /listShort="bcrC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3624038..3624046 /Source="Nicolas_upshift_promotors" /id="U2863" /multdbtbs="-" /comp="M2" /sig="SigI" /pcomp=1 /psig=1 /xcortree=1773 /SigmaFactorBS="actccggatctctttttttgtgcacagaatcCCCCCAGAAac cgcgattcctcTTCGAATTCtcttcaagcgccgttatttcagacaatctctattttta t" /listShort="bcrC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3624045 /Source="Nicolas_upshifts" /id="U2863" /multdbtbs="-" /comp="M2" /sig="SigI" /pcomp=1 /psig=1 /xcortree=1773 /SigmaFactorBS="actccggatctctttttttgtgcacagaatcCCCCCAGAAac cgcgattcctcTTCGAATTCtcttcaagcgccgttatttcagacaatctctattttta t" /listShort="bcrC" /GFF_Attribute="listLong" promotor_-35 3624087..3624096 /Source="Nicolas_upshift_promotors" /id="U2864" /multdbtbs="SigM,SigX" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1653 /SigmaFactorBS="agcgccgttatttcagacaatctctatttttattTGAAACTT TTcatgagtaagatTAGTCTACTAAATATAaaaatgtaaaaggtgattatttgaacta c" /listShort="bcrC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3624109..3624124 /Source="Nicolas_upshift_promotors" /id="U2864" /multdbtbs="SigM,SigX" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1653 /SigmaFactorBS="agcgccgttatttcagacaatctctatttttattTGAAACTT TTcatgagtaagatTAGTCTACTAAATATAaaaatgtaaaaggtgattatttgaacta c" /listShort="bcrC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3624113 /Source="Nicolas_upshifts" /id="U2864" /multdbtbs="SigM,SigX" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1653 /SigmaFactorBS="agcgccgttatttcagacaatctctatttttattTGAAACTT TTcatgagtaagatTAGTCTACTAAATATAaaaatgtaaaaggtgattatttgaacta c" /listShort="bcrC" /GFF_Attribute="listLong" CDS 3624145..3624726 /gene="bcrC" /locus_tag="BSU_36530" /old_locus_tag="BSU36530" /EC_number="3.6.1.27" /function="16.1: Circulate" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:12486040, 14612242, 15838020, 15849754, 15946938, 16850406, 27528508" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12486040, 14612242, 15838020, 15849754, 15946938, 16850406, 27528508; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="undecaprenyl pyrophosphate phosphatase (bacitracin resistance)" /protein_id="NP_391534.1" /db_xref="EnsemblGenomes-Gn:BSU36530" /db_xref="EnsemblGenomes-Tr:CAB15670" /db_xref="GOA:P94571" /db_xref="InterPro:IPR000326" /db_xref="InterPro:IPR033879" /db_xref="InterPro:IPR036938" /db_xref="SubtiList:BG12488" /db_xref="UniProtKB/Swiss-Prot:P94571" /translation="MNYEIFKAIHGLSHHNSVLDSIMVFITEYAIVAYALILLAIWLF GNTQSRKHVLYAGITGIAGLVINYLITLVYFEPRPFVAHTVHTLIPHAADASFPSDHT TGALAISIAMLFRNRKIGWPLVIFGLLTGFSRIWVGHHYPVDVLGSLVVAIIIGFLFF RFSDLLRPFVDLVVRIYEAIINKLTKKPTDQNF*" gene 3624145..3624726 /gene="bcrC" /locus_tag="BSU_36530" /old_locus_tag="BSU36530" promotor_-10 complement(3624243..3624262) /Source="Nicolas_upshift_promotors" /id="U2865" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.793206793206793" /psig="0.793206793206793" /xcortree=1382 /SigmaFactorBS="ctgcgtatagcacatgttttctgctttgtGTGTTCCCAaaca gccagattgCCAATAGGATAAGGGCATAGgcgacaatggcatattccgtgatgaagac c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3624253) /Source="Nicolas_upshifts" /id="U2865" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.793206793206793" /psig="0.793206793206793" /xcortree=1382 /SigmaFactorBS="ctgcgtatagcacatgttttctgctttgtGTGTTCCCAaaca gccagattgCCAATAGGATAAGGGCATAGgcgacaatggcatattccgtgatgaagac c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(3624276..3624284) /Source="Nicolas_upshift_promotors" /id="U2865" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.793206793206793" /psig="0.793206793206793" /xcortree=1382 /SigmaFactorBS="ctgcgtatagcacatgttttctgctttgtGTGTTCCCAaaca gccagattgCCAATAGGATAAGGGCATAGgcgacaatggcatattccgtgatgaagac c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 3624707 /Source="Nicolas_upshifts" /id="D1888" /incds=0 /nref=192 /ntot=251 /MaxReadThrough="2.1929" /MaxDrop="6.53316" /score="25.582072" /energy="-12.5" /TU="NA" /idTUdmin="U2863" /TUdmin=2 /isTUend="TRUE" CDS complement(3624767..3625189) /gene="ywnJ" /locus_tag="BSU_36540" /old_locus_tag="BSU36540" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 14762009, 15849754, 16850406; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative integral inner membrane protein" /protein_id="NP_391535.1" /db_xref="EnsemblGenomes-Gn:BSU36540" /db_xref="EnsemblGenomes-Tr:CAB15671" /db_xref="GOA:P71045" /db_xref="InterPro:IPR006976" /db_xref="SubtiList:BG12487" /db_xref="UniProtKB/Swiss-Prot:P71045" /translation="MNRLLLAGWIFFILLSVCTESFSGMVVSQTVAFHFQPHPDLSQF LVMDFTELTVPEAFIQKIGHAFSFFVLTYLLWKQRGSIRSAAAGSFAFAFFTEVLQLF FSRNGCIRDVLIDAVGIGLFYGLYVLAKRRKQEMYEKY*" gene complement(3624767..3625189) /gene="ywnJ" /locus_tag="BSU_36540" /old_locus_tag="BSU36540" downshifts complement(3624786) /Source="Nicolas_upshifts" /id="D1889" /incds=0 /nref=9 /ntot=75 /MaxReadThrough="0.80227" /MaxDrop="3.65224" /score="4.98901321" /energy="-13.6" /TU="NA" /idTUdmin="U2869" /TUdmin=215 /isTUend="FALSE" promotor_-10 complement(3625224..3625239) /Source="Nicolas_upshift_promotors" /id="U2866" /multdbtbs="SigW,SigX" /comp="M9" /sig="SigWXY" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1654 /SigmaFactorBS="ttaatgaagaaaacgtctatccttgtgatgggcgtttttttc TGTTACTTTTtgctttgttttaCCGTCTATGTAGTTACatgtaggcacgtacgttata a" /listShort="ywnJ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3625243) /Source="Nicolas_upshifts" /id="U2866" /multdbtbs="SigW,SigX" /comp="M9" /sig="SigWXY" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1654 /SigmaFactorBS="ttaatgaagaaaacgtctatccttgtgatgggcgtttttttc TGTTACTTTTtgctttgttttaCCGTCTATGTAGTTACatgtaggcacgtacgttata a" /listShort="ywnJ" /GFF_Attribute="listLong" promotor_-35 complement(3625252..3625261) /Source="Nicolas_upshift_promotors" /id="U2866" /multdbtbs="SigW,SigX" /comp="M9" /sig="SigWXY" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1654 /SigmaFactorBS="ttaatgaagaaaacgtctatccttgtgatgggcgtttttttc TGTTACTTTTtgctttgttttaCCGTCTATGTAGTTACatgtaggcacgtacgttata a" /listShort="ywnJ" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3625300..3626151) /gene="spoIIQ" /locus_tag="BSU_36550" /old_locus_tag="BSU36550" /function="16.8: Protect" /function="16.6: Maintain" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:16164552, 16959571, 17121846, 18077456, 21097616, 23859254, 26929302, 27381174, 28784753" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16164552, 16959571, 17121846, 18077456, 21097616, 23859254, 26929302, 27381174, 28784753; Product type f: factor" /codon_start=1 /transl_table=11 /product="forespore protein required for alternative engulfment" /protein_id="NP_391536.1" /db_xref="EnsemblGenomes-Gn:BSU36550" /db_xref="EnsemblGenomes-Tr:CAB15672" /db_xref="GOA:P71044" /db_xref="InterPro:IPR011055" /db_xref="InterPro:IPR016047" /db_xref="PDB:3TUF" /db_xref="PDB:3UZ0" /db_xref="SubtiList:BG11978" /db_xref="UniProtKB/Swiss-Prot:P71044" /translation="MREEEKKTSQVKKLQQFFRKRWVFPAIYLVSAAVILTAVLWYQS VSNDEVKDQLADNGGNSAYDNNDDAVEVGKSMENVAMPVVDSENVSVVKKFYETDAAK EEKEAALVTYNNTYSLSKGIDLAEKDGKDFDVSASLSGTVVKAEKDPVLGYVVEVEHA DGLSTVYQSLSEVSVEQGDKVKQNQVIGKSGKNLYSEDSGNHVHFEIRKDGVAMNPLN FMDKPVSSIEKAATQETEESIQQSSEKKDGSTEKGTEEKSGEKKDDSTDKSGSKESST TEDTEQS*" gene complement(3625300..3626151) /gene="spoIIQ" /locus_tag="BSU_36550" /old_locus_tag="BSU36550" downshifts complement(3625309) /Source="Nicolas_upshifts" /id="D1890" /incds=0 /nref=19 /ntot=51 /MaxReadThrough="3.592" /MaxDrop="5.16472" /score="11.9597238" /energy="-7.1" /TU="U2869" /idTUdmin="U2866" /TUdmin="-176" /isTUend="FALSE" downshifts complement(3625551) /Source="Nicolas_upshifts" /id="D1891" /incds=1 /nref=4 /ntot=59 /MaxReadThrough="6.6416" /MaxDrop="3.0034" /score="11.9597238" /energy="-7.1" /TU="U2869" /idTUdmin="U2866" /TUdmin="-418" /isTUend="FALSE" promotor_-35 3625788..3625790 /Source="Nicolas_upshift_promotors" /id="U2867" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.578421578421578" /psig="0.999000999001" /xcortree=2749 /SigmaFactorBS="gagacatcgaaatcttttccgtctttctcagctaagtcaaTT CctttgcttaggctgtaCGTGTTATTATAGGTAACGAgtgctgcttctttctcttctt t" /listShort="S1406, S1407, ywnH, ywnG" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3625807..3625826 /Source="Nicolas_upshift_promotors" /id="U2867" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.578421578421578" /psig="0.999000999001" /xcortree=2749 /SigmaFactorBS="gagacatcgaaatcttttccgtctttctcagctaagtcaaTT CctttgcttaggctgtaCGTGTTATTATAGGTAACGAgtgctgcttctttctcttctt t" /listShort="S1406, S1407, ywnH, ywnG" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 3625808..3626154 /Source="Nicolas_S_feature" /locus_tag="new_3760210_3760556" /HighExp="LBGstat, LBGtran, Cold, Sw, dia15, C30, G180, Lbexp, LBGexp, UNK1" /AntisenseName="spoIIQ" /AntisenseCor="-0.81767802234568998" /AntisenseRegPval="-65.3" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S1406" upshifts 3625808 /Source="Nicolas_upshifts" /id="U2867" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.578421578421578" /psig="0.999000999001" /xcortree=2749 /SigmaFactorBS="gagacatcgaaatcttttccgtctttctcagctaagtcaaTT CctttgcttaggctgtaCGTGTTATTATAGGTAACGAgtgctgcttctttctcttctt t" /listShort="S1406, S1407, ywnH, ywnG" /GFF_Attribute="listLong" misc_feature 3626146..3626149 /Source="Nicolas_upshift_promotors" /id="U2868" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.27972027972028" /psig="0.121878121878122" /xcortree=579 /SigmaFactorBS="cgaaaaaactgctgaagttttttgacttgagaagttttcttt tcttcctcTCTCattgtttcatcacctcagcaacattctgaacacttttctgaaaata t" /listShort="S1407, ywnH, ywnG" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" S_feature 3626156..3626291 /Source="Nicolas_S_feature" /locus_tag="new_3760558_3760693" /HighExp="LBGstat, S8, LBGtran, Sw, LoTm, BC, Cold, S7, C30, Lbexp" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="Sig-, SigA" /TUshortPSig="0.122, 0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S1407" upshifts 3626156 /Source="Nicolas_upshifts" /id="U2868" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.27972027972028" /psig="0.121878121878122" /xcortree=579 /SigmaFactorBS="cgaaaaaactgctgaagttttttgacttgagaagttttcttt tcttcctcTCTCattgtttcatcacctcagcaacattctgaacacttttctgaaaata t" /listShort="S1407, ywnH, ywnG" /GFF_Attribute="listLong" upshifts complement(3626185) /Source="Nicolas_upshifts" /id="U2869" /multdbtbs="SigF" /comp="M3" /sig="SigEF" /pcomp="0.933066933066933" /psig="0.933066933066933" /xcortree=974 /SigmaFactorBS="tcagtctgtgcaaactacatctaaaaaagtttttttggatag gttGTATATATTTtcagaaaagtgttcagaatgttgctgaggtgatgaaacaatgaga g" /listShort="spoIIQ, ywnJ" /GFF_Attribute="listLong" misc_feature complement(3626191..3626200) /Source="Nicolas_upshift_promotors" /id="U2869" /multdbtbs="SigF" /comp="M3" /sig="SigEF" /pcomp="0.933066933066933" /psig="0.933066933066933" /xcortree=974 /SigmaFactorBS="tcagtctgtgcaaactacatctaaaaaagtttttttggatag gttGTATATATTTtcagaaaagtgttcagaatgttgctgaggtgatgaaacaatgaga g" /listShort="spoIIQ, ywnJ" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" CDS 3626292..3626783 /gene="ywnH" /locus_tag="BSU_36560" /old_locus_tag="BSU36560" /EC_number="2.3.1.183" /function="16.8: Protect" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 12793527, 16021622, 27694229; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative aminoacid analogs (phosphinothricin) N-acetyltransferase" /protein_id="NP_391537.1" /db_xref="EnsemblGenomes-Gn:BSU36560" /db_xref="EnsemblGenomes-Tr:CAB15673" /db_xref="GOA:P71043" /db_xref="InterPro:IPR000182" /db_xref="InterPro:IPR016181" /db_xref="PDB:1VHS" /db_xref="SubtiList:BG12486" /db_xref="UniProtKB/Swiss-Prot:P71043" /translation="MTLRLAEHRDLEAVVAIYNSTIASRMVTADTEPVTPEDRMEWFS GHTESRPLYVAEDENGNVAAWISFETFYGRPAYNKTAEVSIYIDEACRGKGVGSYLLQ EALRIAPNLGIRSLMAFIFGHNKPSLKLFEKHGFAEWGLFPGIAEMDGKRYDLKILGR ELS*" gene 3626292..3626783 /gene="ywnH" /locus_tag="BSU_36560" /old_locus_tag="BSU36560" promotor_-35 3626521..3626526 /Source="Nicolas_upshift_promotors" /id="U2870" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1178 /SigmaFactorBS="tttgaaacattttatggaaggccagcctATAATAaaacagcg gaagtcaGCATATACATTGACGAAGCatgccgcggcaaaggtgttggatcatatttgc t" /listShort="ywnG" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3626542..3626560 /Source="Nicolas_upshift_promotors" /id="U2870" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1178 /SigmaFactorBS="tttgaaacattttatggaaggccagcctATAATAaaacagcg gaagtcaGCATATACATTGACGAAGCatgccgcggcaaaggtgttggatcatatttgc t" /listShort="ywnG" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3626553 /Source="Nicolas_upshifts" /id="U2870" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1178 /SigmaFactorBS="tttgaaacattttatggaaggccagcctATAATAaaacagcg gaagtcaGCATATACATTGACGAAGCatgccgcggcaaaggtgttggatcatatttgc t" /listShort="ywnG" /GFF_Attribute="listLong" S_feature complement(3626644..3627552) /Source="Nicolas_S_feature" /locus_tag="new_3761046_3761954_c" /HighExp="H2O2, dia15, Diami, dia5, S8, Paraq, G180, G135, C30, G150" /AntisenseName="ywnG" /AntisenseCor="0.27407310266030799" /AntisenseRegPval="-5.3" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.946" /TUlongSig="NA" /TUlongPSig="NA" /label="S1408" CDS 3626780..3627298 /gene="ywnG" /locus_tag="BSU_36570" /old_locus_tag="BSU36570" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406, 22226636; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative integral inner membrane protein" /protein_id="NP_391538.1" /db_xref="EnsemblGenomes-Gn:BSU36570" /db_xref="EnsemblGenomes-Tr:CAB15674" /db_xref="GOA:P71042" /db_xref="InterPro:IPR035287" /db_xref="SubtiList:BG12485" /db_xref="UniProtKB/Swiss-Prot:P71042" /translation="MISLDKDENEIEHHNEENSLVEQETAPVGQESRQLSASAVKSLS DIAKWGKISGILLIIMGSLVTLSVLMTVIGAIPGVLLIISGVFLMRSAKAAAEAEGNL TGSAGESMLENYGTFIKMQLFYAASSIVTVLIGIIVAIFVLVVIGIAAFENTPSYDDP DSYYYEDDPVFE*" gene 3626780..3627298 /gene="ywnG" /locus_tag="BSU_36570" /old_locus_tag="BSU36570" downshifts 3627103 /Source="Nicolas_upshifts" /id="D1892" /incds=1 /nref=1 /ntot=29 /MaxReadThrough="4.194" /MaxDrop="1.82458" /score="-3.39058903" /energy="-13.3" /TU="U2867,U2868,U2870" /idTUdmin="U2868" /TUdmin="-44" /isTUend="FALSE" downshifts 3627301 /Source="Nicolas_upshifts" /id="D1893" /incds=0 /nref=3 /ntot=133 /MaxReadThrough="2.87136" /MaxDrop="2.9486" /score="-3.39058903" /energy="-13.3" /TU="U2867" /idTUdmin="U2870" /TUdmin=0 /isTUend="TRUE" CDS 3627457..3627588 /locus_tag="BSU_36575" /old_locus_tag="BSU36575" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_009514007.1" /translation="MNIKKTDEVGINPKPHFLFRVSACKKTHPDRLENLNNPGADLL* " gene 3627457..3627588 /locus_tag="BSU_36575" /old_locus_tag="BSU36575" CDS complement(3627585..3628019) /gene="ywnF" /locus_tag="BSU_36580" /old_locus_tag="BSU36580" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_391539.1" /db_xref="EnsemblGenomes-Gn:BSU36580" /db_xref="EnsemblGenomes-Tr:CAB15675" /db_xref="GOA:P71041" /db_xref="InterPro:IPR020205" /db_xref="SubtiList:BG12484" /db_xref="UniProtKB/Swiss-Prot:P71041" /translation="MNFYRVEQMPGFIKTEMQKIQKAVQPFMKKTVIYRFLAIPLAAF SLFNLAAFLFHASADRESLISAGIFALLAALGLAFFKEAGYQHKQIQKTVHIYMLNRI KKSEILSEERKSSYARQIKEEPFAMRSFVEFLTEEDRRKKMY*" gene complement(3627585..3628019) /gene="ywnF" /locus_tag="BSU_36580" /old_locus_tag="BSU36580" downshifts complement(3627597) /Source="Nicolas_upshifts" /id="D1894" /incds=0 /nref=174 /ntot=254 /MaxReadThrough="4.22489" /MaxDrop="5.35802" /score="21.5198482" /energy="-21.3" /TU="U2871" /idTUdmin="U2873" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(3628068..3628087) /Source="Nicolas_upshift_promotors" /id="U2871" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.887112887112887" /psig="0.946053946053946" /xcortree=631 /SigmaFactorBS="attcttcgtgaaaaatacgggcagatTTCTTTAAaaccagct tgcaccTGCGTTAAAATAAACACATAtgataacgttcgtgaagcttgaaacatcaaat a" /listShort="ywnF, S1408" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3628075) /Source="Nicolas_upshifts" /id="U2871" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.887112887112887" /psig="0.946053946053946" /xcortree=631 /SigmaFactorBS="attcttcgtgaaaaatacgggcagatTTCTTTAAaaccagct tgcaccTGCGTTAAAATAAACACATAtgataacgttcgtgaagcttgaaacatcaaat a" /listShort="ywnF, S1408" /GFF_Attribute="listLong" S_feature complement(3628077..3628374) /Source="Nicolas_S_feature" /locus_tag="new_3762479_3762776_c" /HighExp="Etha, S6, S3, S4, S8, S5, S7, M9-stat, Sw, Salt" /AntisenseName="clsA" /AntisenseCor="-0.16109419145114601" /AntisenseRegPval="-2.1" /CDS_PredictionProba="NA" /TUshortSig="SigB, SigEF" /TUshortPSig="0.99, 0.997" /TUlongSig="NA" /TUlongPSig="NA" /label="S1409" promotor_-35 complement(3628102..3628109) /Source="Nicolas_upshift_promotors" /id="U2871" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.887112887112887" /psig="0.946053946053946" /xcortree=631 /SigmaFactorBS="attcttcgtgaaaaatacgggcagatTTCTTTAAaaccagct tgcaccTGCGTTAAAATAAACACATAtgataacgttcgtgaagcttgaaacatcaaat a" /listShort="ywnF, S1408" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 3628148..3628152 /Source="Nicolas_upshift_promotors" /id="U2872" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.987012987012987" /psig=1 /xcortree=1840 /SigmaFactorBS="ttttcacgaagaatctggatcgccgcTCTTTattcttttaaa atgtgAGTGTTATAATTTGTAATGGgaatcagatcactgttattcatggaatactaat g" /listShort="S1410, clsA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3628169..3628188 /Source="Nicolas_upshift_promotors" /id="U2872" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.987012987012987" /psig=1 /xcortree=1840 /SigmaFactorBS="ttttcacgaagaatctggatcgccgcTCTTTattcttttaaa atgtgAGTGTTATAATTTGTAATGGgaatcagatcactgttattcatggaatactaat g" /listShort="S1410, clsA" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 3628181..3628261 /Source="Nicolas_S_feature" /locus_tag="new_3762583_3762663" /HighExp="LBGstat, Diami, dia15, G180, Oxctl, H2O2, T0.30H, S8, Paraq, G135" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1410" upshifts 3628182 /Source="Nicolas_upshifts" /id="U2872" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.987012987012987" /psig=1 /xcortree=1840 /SigmaFactorBS="ttttcacgaagaatctggatcgccgcTCTTTattcttttaaa atgtgAGTGTTATAATTTGTAATGGgaatcagatcactgttattcatggaatactaat g" /listShort="S1410, clsA" /GFF_Attribute="listLong" CDS 3628262..3629710 /gene="clsA" /locus_tag="BSU_36590" /old_locus_tag="BSU36590" /EC_number="2.7.8.-" /function="16.8: Protect" /function="16.2: Construct biomass (Anabolism)" /function="16.6: Maintain" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:14973018, 16755131, 18820022, 26708983" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 14973018, 16755131, 18820022, 26708983; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="cardiolipin synthase (major)" /protein_id="NP_391540.1" /db_xref="EnsemblGenomes-Gn:BSU36590" /db_xref="EnsemblGenomes-Tr:CAB15676" /db_xref="GOA:P71040" /db_xref="InterPro:IPR000515" /db_xref="InterPro:IPR001736" /db_xref="InterPro:IPR022924" /db_xref="InterPro:IPR025202" /db_xref="InterPro:IPR027379" /db_xref="InterPro:IPR030874" /db_xref="SubtiList:BG12483" /db_xref="UniProtKB/Swiss-Prot:P71040" /translation="MSISSILLSLFFILNILLAIIVIFKERRDASASWAWLLVLFFIP VLGFILYLLFGHNLRRKHLFQWEDRKKIGIERLLKHQLEDLETKQFQFNNRATFDNKD LIYMLIMNNHAVFTEDNSVDVITDGRDKFQRLLSDISKAKDHIHLQYYIYKGDELGKK LRDALIQKAKEGVQVRVLYDELGSRTLRKKFFKELREAGGHVEVFFPSKLRPINLRLN YRNHRKLVIIDGMTGYVGGFNVGDEYLGLNPKFGYWRDTHIRLQGTAVHAIQTRFILD WNQASHHHTLTYIPNHFPDYGPKGNVGMQIVTSGPDSEWEQIKNGYIKMISNAKRSIL IQTPYFIPDASLLDALRIACLSGIDVNIMIPNKPDHAFVYWATLSYIGDLLKAGATVY IYDNGFIHAKTIVVDDEIASVGTANIDVRSFRLNFEVNAFIYDITIAKKLVSTFKEDL LVSRKFTYEEYLQRPLWIRIKESVSRLLSPIL*" gene 3628262..3629710 /gene="clsA" /locus_tag="BSU_36590" /old_locus_tag="BSU36590" upshifts complement(3628374) /Source="Nicolas_upshifts" /id="U2873" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.99000999000999" /psig="0.99000999000999" /xcortree=743 /SigmaFactorBS="agattatggccgaataataAGTATAAaataaagcctaaaacG GGAATAAAGAAAAGAACAagcagccacgcccaagatgcactggcatcgcgccgttctt t" /listShort="S1409, ywnF" /GFF_Attribute="listLong" promotor_-10 complement(3628375..3628393) /Source="Nicolas_upshift_promotors" /id="U2873" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.99000999000999" /psig="0.99000999000999" /xcortree=743 /SigmaFactorBS="agattatggccgaataataAGTATAAaataaagcctaaaacG GGAATAAAGAAAAGAACAagcagccacgcccaagatgcactggcatcgcgccgttctt t" /listShort="S1409, ywnF" /GFF_Attribute="listLong" /label="promotor_-10" S_feature complement(3628376..3628719) /Source="Nicolas_S_feature" /locus_tag="new_3762778_3763121_c" /HighExp="S6, S8, S4, S5, S7, S3, T5.0H, M9-stat, C30, T4.0H" /AntisenseName="clsA" /AntisenseCor="3.3648966966722899E-2" /AntisenseRegPval="-0.2" /CDS_PredictionProba="NA" /TUshortSig="SigEF" /TUshortPSig="0.997" /TUlongSig="NA" /TUlongPSig="NA" /label="S1411" promotor_-35 complement(3628409..3628415) /Source="Nicolas_upshift_promotors" /id="U2873" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.99000999000999" /psig="0.99000999000999" /xcortree=743 /SigmaFactorBS="agattatggccgaataataAGTATAAaataaagcctaaaacG GGAATAAAGAAAAGAACAagcagccacgcccaagatgcactggcatcgcgccgttctt t" /listShort="S1409, ywnF" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(3628697..3628715) /Source="Nicolas_upshift_promotors" /id="U2874" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=1084 /SigmaFactorBS="acaccttctttcgccttttggatgagagcgtcccgcaatttt tTGCCTAattcatcgcctttatAAATATAATACTGTAAATGgatatgatccttagcct t" /listShort="S1411, S1409, ywnF" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3628719) /Source="Nicolas_upshifts" /id="U2874" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=1084 /SigmaFactorBS="acaccttctttcgccttttggatgagagcgtcccgcaatttt tTGCCTAattcatcgcctttatAAATATAATACTGTAAATGgatatgatccttagcct t" /listShort="S1411, S1409, ywnF" /GFF_Attribute="listLong" promotor_-35 complement(3628731..3628736) /Source="Nicolas_upshift_promotors" /id="U2874" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=1084 /SigmaFactorBS="acaccttctttcgccttttggatgagagcgtcccgcaatttt tTGCCTAattcatcgcctttatAAATATAATACTGTAAATGgatatgatccttagcct t" /listShort="S1411, S1409, ywnF" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 3629699 /Source="Nicolas_upshifts" /id="D1895" /incds=0 /nref=6 /ntot=214 /MaxReadThrough="0.7051" /MaxDrop="4.44298" /score="26.7449315" /energy="-19.5" /TU="NA" /idTUdmin="U2872" /TUdmin=0 /isTUend="TRUE" CDS complement(3629731..3630504) /gene="mta" /locus_tag="BSU_36600" /old_locus_tag="BSU36600" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:10200972, 11581256, 18502870" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10200972, 11581256, 18502870; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator regulating efflux transporters synthesis (Fur-independent bacillibactin export)" /protein_id="NP_391541.1" /db_xref="EnsemblGenomes-Gn:BSU36600" /db_xref="EnsemblGenomes-Tr:CAB15677" /db_xref="GOA:P71039" /db_xref="InterPro:IPR000551" /db_xref="InterPro:IPR009061" /db_xref="InterPro:IPR012925" /db_xref="InterPro:IPR036244" /db_xref="PDB:1JBG" /db_xref="PDB:1R8D" /db_xref="SubtiList:BG12482" /db_xref="UniProtKB/Swiss-Prot:P71039" /translation="MKYQVKQVAEISGVSIRTLHHYDNIELLNPSALTDAGYRLYSDA DLERLQQILFFKEIGFRLDEIKEMLDHPNFDRKAALQSQKEILMKKKQRMDEMIQTID RTLLSVDGGETMNKRDLFAGLSMKDIEEHQQTYADEVRKLYGKEIAEETEKRTSAYSA DDWRTIMAEFDSIYRRIAARMKHGPDDAEIQAAVGAFRDHICQYHYDCTLDIFRGLGE VYITDERFTDSINQYGEGLAAFLREAIIIYCDHQENPRP*" gene complement(3629731..3630504) /gene="mta" /locus_tag="BSU_36600" /old_locus_tag="BSU36600" downshifts complement(3629753) /Source="Nicolas_upshifts" /id="D1896" /incds=0 /nref=1 /ntot=54 /MaxReadThrough="0.46006" /MaxDrop="2.97389" /score="11.4339746" /energy="-19.5" /TU="NA" /idTUdmin="U2876" /TUdmin=1342 /isTUend="FALSE" promotor_-35 3630579..3630582 /Source="Nicolas_upshift_promotors" /id="U2875" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.85914085914086" /psig="0.982017982017982" /xcortree=2618 /SigmaFactorBS="caacgttagggtcaatccccaaaatgttattttctatATACa aaacttctcacaaaTAGTGTATAAAAGAAAAGTGagtatttttttgtaaaggggagcc a" /listShort="ywnC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3630598..3630617 /Source="Nicolas_upshift_promotors" /id="U2875" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.85914085914086" /psig="0.982017982017982" /xcortree=2618 /SigmaFactorBS="caacgttagggtcaatccccaaaatgttattttctatATACa aaacttctcacaaaTAGTGTATAAAAGAAAAGTGagtatttttttgtaaaggggagcc a" /listShort="ywnC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3630602 /Source="Nicolas_upshifts" /id="U2875" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.85914085914086" /psig="0.982017982017982" /xcortree=2618 /SigmaFactorBS="caacgttagggtcaatccccaaaatgttattttctatATACa aaacttctcacaaaTAGTGTATAAAAGAAAAGTGagtatttttttgtaaaggggagcc a" /listShort="ywnC" /GFF_Attribute="listLong" CDS 3630649..3631032 /gene="ywnC" /locus_tag="BSU_36610" /old_locus_tag="BSU36610" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative integral inner membrane protein" /protein_id="NP_391542.1" /db_xref="EnsemblGenomes-Gn:BSU36610" /db_xref="EnsemblGenomes-Tr:CAB15678" /db_xref="GOA:P71038" /db_xref="InterPro:IPR035287" /db_xref="SubtiList:BG12481" /db_xref="UniProtKB/Swiss-Prot:P71038" /translation="MNPETMNKTLISISKWGKATGILFIIMGAITALSGAFFFLIGAV PGVLQIISGIFLMRSAREAGQMAEHNSGQSEDLMLENYAKFVKMQGIYLIVSIAVSIL AIIAFFIFLMLGIADGLFSDTYSTY*" gene 3630649..3631032 /gene="ywnC" /locus_tag="BSU_36610" /old_locus_tag="BSU36610" downshifts 3631019 /Source="Nicolas_upshifts" /id="D1897" /incds=0 /nref=60 /ntot=180 /MaxReadThrough="1.0319" /MaxDrop="4.45212" /score="35.5991488" /energy="-11.4" /TU="NA" /idTUdmin="U2875" /TUdmin=0 /isTUend="TRUE" CDS complement(3631067..3631708) /gene="ywnB" /locus_tag="BSU_36620" /old_locus_tag="BSU36620" /EC_number="1.-.-.-" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative oxidoreductase" /protein_id="NP_391543.1" /db_xref="EnsemblGenomes-Gn:BSU36620" /db_xref="EnsemblGenomes-Tr:CAB15679" /db_xref="InterPro:IPR016040" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG12480" /db_xref="UniProtKB/Swiss-Prot:P71037" /translation="MKIGIIGASGKAGNEILKEAKKRGHEVTAIVRNASKVQEQDVAI LEKDVFELTAEDIKPFDAVVNAFGAAPGQEHLHVEAGRALISILKDAKHTRLLVVGGA GSLFVDEAKTTRLMDTPEFPKEYLPTASNQGENLKDLQQTDSISWTFLSPAAFFDPAG KRTGSYQKGKDNVIVNAKGDSYISYADYAIAVLDELEHPEHKNERFTVVSEAE*" gene complement(3631067..3631708) /gene="ywnB" /locus_tag="BSU_36620" /old_locus_tag="BSU36620" downshifts complement(3631117) /Source="Nicolas_upshifts" /id="D1898" /incds=0 /nref=20 /ntot=170 /MaxReadThrough="3.62026" /MaxDrop="4.98934" /score="21.1363072" /energy="-11.4" /TU="U2876" /idTUdmin="U2876" /TUdmin="-22" /isTUend="TRUE" CDS complement(3631776..3632177) /gene="ywnA" /locus_tag="BSU_36630" /old_locus_tag="BSU36630" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative transcriptional regulator" /protein_id="NP_391544.1" /db_xref="EnsemblGenomes-Gn:BSU36630" /db_xref="EnsemblGenomes-Tr:CAB15680" /db_xref="GOA:P71036" /db_xref="InterPro:IPR000944" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="PDB:1XD7" /db_xref="SubtiList:BG12479" /db_xref="UniProtKB/Swiss-Prot:P71036" /translation="MINSRLAVAIHILSLISMDEKTSSEIIADSVNTNPVVVRRMISL LKKADILTSRAGVPGASLKKDPADISLLEVYRAVQKQEELFAVHENPNPKCPVGKKIQ NALDETFESVQRAMENELASKSLKDVMNHLF*" gene complement(3631776..3632177) /gene="ywnA" /locus_tag="BSU_36630" /old_locus_tag="BSU36630" promotor_-10 complement(3632226..3632245) /Source="Nicolas_upshift_promotors" /id="U2876" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.385614385614386" /psig="0.993006993006993" /xcortree=1847 /SigmaFactorBS="gtgcatccggccgttctattgactaaaaacgGTGCACaaaac ccatgtattTAGTGTATATTAGATGTTGAcaaacgaatcaaatgtaactattatagtt a" /listShort="ywnA, ywnB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3632236) /Source="Nicolas_upshifts" /id="U2876" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.385614385614386" /psig="0.993006993006993" /xcortree=1847 /SigmaFactorBS="gtgcatccggccgttctattgactaaaaacgGTGCACaaaac ccatgtattTAGTGTATATTAGATGTTGAcaaacgaatcaaatgtaactattatagtt a" /listShort="ywnA, ywnB" /GFF_Attribute="listLong" S_feature complement(3632238..3632311) /Source="Nicolas_S_feature" /locus_tag="new_3766640_3766713_c" /HighExp="BT, Etha, S1, B60, LoTm, B36, S2, Glucon, Sw, T0.30H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.18507799999999999" /TUshortSig="Sig-" /TUshortPSig="0.106" /TUlongSig="SigH, SigA, SigB, SigB" /TUlongPSig="1, 0.993, 1, 0.995" /label="S1412" promotor_-35 complement(3632260..3632265) /Source="Nicolas_upshift_promotors" /id="U2876" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.385614385614386" /psig="0.993006993006993" /xcortree=1847 /SigmaFactorBS="gtgcatccggccgttctattgactaaaaacgGTGCACaaaac ccatgtattTAGTGTATATTAGATGTTGAcaaacgaatcaaatgtaactattatagtt a" /listShort="ywnA, ywnB" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3632312..3634021) /gene="ureC" /locus_tag="BSU_36640" /old_locus_tag="BSU36640" /EC_number="3.5.1.5" /function="16.8: Protect" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:9287005, 12401490, 16199586" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9287005, 12401490, 16199586; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="urease (alpha subunit)" /protein_id="NP_391545.1" /db_xref="EnsemblGenomes-Gn:BSU36640" /db_xref="EnsemblGenomes-Tr:CAB15681" /db_xref="GOA:P77837" /db_xref="InterPro:IPR005848" /db_xref="InterPro:IPR006680" /db_xref="InterPro:IPR011059" /db_xref="InterPro:IPR011612" /db_xref="InterPro:IPR017950" /db_xref="InterPro:IPR017951" /db_xref="InterPro:IPR029754" /db_xref="InterPro:IPR032466" /db_xref="SubtiList:BG11983" /db_xref="UniProtKB/Swiss-Prot:P77837" /translation="MKMSREEYAELFGPTTGDKIRLGDTDLWIEVEKDFTVYGEEMIF GGGKTIRDGMGQNGRITGKDGALDLVITNVVLLDYTGIVKADVGVKDGRIVGVGKSGN PDIMDGVDPHMVIGAGTEVISGEGKILTAGGVDTHIHFICPQQMEVALSSGVTTLLGG GTGPATGSKATTCTSGAWYMARMLEAAEEFPINVGFLGKGNASDKAPLIEQVEAGAIG LKLHEDWGTTPSAIKTCMEVVDEADIQVAIHTDTINEAGFLENTLDAIGDRVIHTYHI EGAGGGHAPDIMKLASYANILPSSTTPTIPYTVNTMDEHLDMMMVCHHLDAKVPEDVA FSHSRIRAATIAAEDILHDIGAISMTSSDSQAMGRVGEVIIRTWQVADKMKKQRGALA GENGNDNVRAKRYIAKYTINPAITHGLSHEVGSVEKGKLADLVLWDPVFFGVKPELVL KGGMIARAQMGDPNASIPTPEPVFMRQMYASYGKANRSTSITFMSQASIERGVAESLG LEKRISPVKNIRKLSKLDMKLNSALPKIEIDPKTYQVFADGEELSCQPVDYVPLGQRY FLF*" gene complement(3632312..3634021) /gene="ureC" /locus_tag="BSU_36640" /old_locus_tag="BSU36640" CDS complement(3634018..3634392) /gene="ureB" /locus_tag="BSU_36650" /old_locus_tag="BSU36650" /EC_number="3.5.1.5" /function="16.8: Protect" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:9287005, 12401490, 16199586" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9287005, 12401490, 16199586; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="urease (beta subunit)" /protein_id="NP_391546.1" /db_xref="EnsemblGenomes-Gn:BSU36650" /db_xref="EnsemblGenomes-Tr:CAB15682" /db_xref="GOA:P71035" /db_xref="InterPro:IPR002019" /db_xref="InterPro:IPR036461" /db_xref="SubtiList:BG11982" /db_xref="UniProtKB/Swiss-Prot:P71035" /translation="MKPGAFQIAEGTITINEGREIREVTVKNTGSRSIQVGSHFHFAE ANGALLFDRELAIGMRLDVPSGTSVRFEPGEQKTVSLVEIRGRKTIRGLNGMADTFID ERGKEKTLANLKQAGWMEGVIR*" gene complement(3634018..3634392) /gene="ureB" /locus_tag="BSU_36650" /old_locus_tag="BSU36650" CDS complement(3634389..3634706) /gene="ureA" /locus_tag="BSU_36660" /old_locus_tag="BSU36660" /EC_number="3.5.1.5" /function="16.11: Scavenge (Catabolism)" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:9287005, 12401490, 16199586" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9287005, 12401490, 16199586; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="urease (gamma subunit)" /protein_id="NP_391547.1" /db_xref="EnsemblGenomes-Gn:BSU36660" /db_xref="EnsemblGenomes-Tr:CAB15683" /db_xref="GOA:P75030" /db_xref="InterPro:IPR002026" /db_xref="InterPro:IPR012010" /db_xref="InterPro:IPR036463" /db_xref="SubtiList:BG11981" /db_xref="UniProtKB/Swiss-Prot:P75030" /translation="MKLTPVEQEKLLIFAAGELAKQRKARGVLLNYPEAAAYITCFIM EGARDGKGVAELMEAGRHVLTEKDVMEGVPEMLDSIQVEATFPDGVKLVTVHQPISAE VKS*" gene complement(3634389..3634706) /gene="ureA" /locus_tag="BSU_36660" /old_locus_tag="BSU36660" S_feature complement(3634707..3634791) /Source="Nicolas_S_feature" /locus_tag="new_3769109_3769193_c" /HighExp="BT, B60, B36, S1, Etha, LoTm, M9-stat, S2, T0.30H, BC" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="Sig-, SigH, SigB" /TUshortPSig="0.106, 1, 1" /TUlongSig="SigA, SigB" /TUlongPSig="0.993, 0.995" /label="S1413" upshifts complement(3634791) /Source="Nicolas_upshifts" /id="U2877" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.525474525474525" /psig="0.105894105894106" /xcortree=402 /SigmaFactorBS="gatgaagaaacggcatgccgctttgaaaggcatcttaccgta tgaCCCCCATTCTCGAAgaaagggaggtgatgtcccgcctgactgttccgcaaattcg t" /listShort="S1413, ureA, ureB, ureC, S1412, ywnA" /GFF_Attribute="listLong" misc_feature complement(3634793..3634806) /Source="Nicolas_upshift_promotors" /id="U2877" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.525474525474525" /psig="0.105894105894106" /xcortree=402 /SigmaFactorBS="gatgaagaaacggcatgccgctttgaaaggcatcttaccgta tgaCCCCCATTCTCGAAgaaagggaggtgatgtcccgcctgactgttccgcaaattcg t" /listShort="S1413, ureA, ureB, ureC, S1412, ywnA" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" S_feature complement(3634793..3634886) /Source="Nicolas_S_feature" /locus_tag="new_3769195_3769288_c" /HighExp="BT, Etha, B60, S1, B36, BC, S2, LoTm, T3.0H, T3.30H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.30781199999999997" /TUshortSig="SigH, SigB" /TUshortPSig="1, 1" /TUlongSig="SigA, SigB" /TUlongPSig="0.993, 0.995" /label="S1414" CDS complement(3634887..3635051) /gene="ywzE" /locus_tag="BSU_36668" /old_locus_tag="BSU36668" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function (putative phage interference protein)" /protein_id="YP_009514008.1" /translation="MVNLKNILLNKQLEGIQILIVELVRQVIIEISRKKDICYLSRAQ SGKRVNLIFP*" gene complement(3634887..3635051) /gene="ywzE" /locus_tag="BSU_36668" /old_locus_tag="BSU36668" promotor_-10 complement(3634974..3634992) /Source="Nicolas_upshift_promotors" /id="U2878" /multdbtbs="SigH" /comp="M1" /sig="SigH" /pcomp=1 /psig=1 /xcortree=403 /SigmaFactorBS="aaatctgaaaaatattttacttaataaacaattgGAAGGAAT TcagattttaatTGTCGAACTAGTCAGACAAgttattatagaaatttccagaaaaaaa g" /listShort="S1414, S1413, ureA, ureB, ureC" /listLong="S1412, ywnA" /label="promotor_-10" upshifts complement(3634986) /Source="Nicolas_upshifts" /id="U2878" /multdbtbs="SigH" /comp="M1" /sig="SigH" /pcomp=1 /psig=1 /xcortree=403 /SigmaFactorBS="aaatctgaaaaatattttacttaataaacaattgGAAGGAAT TcagattttaatTGTCGAACTAGTCAGACAAgttattatagaaatttccagaaaaaaa g" /listShort="S1414, S1413, ureA, ureB, ureC" /listLong="S1412, ywnA" promotor_-35 complement(3635004..3635012) /Source="Nicolas_upshift_promotors" /id="U2878" /multdbtbs="SigH" /comp="M1" /sig="SigH" /pcomp=1 /psig=1 /xcortree=403 /SigmaFactorBS="aaatctgaaaaatattttacttaataaacaattgGAAGGAAT TcagattttaatTGTCGAACTAGTCAGACAAgttattatagaaatttccagaaaaaaa g" /listShort="S1414, S1413, ureA, ureB, ureC" /listLong="S1412, ywnA" /label="promotor_-35" S_feature complement(3635052..3635223) /Source="Nicolas_S_feature" /locus_tag="new_3769454_3769625_c" /HighExp="Etha, BT, S1, GM-0.2, GM-0.1, Salt, GM 5, T-5.40H, MG 60, MG 120" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigB" /TUshortPSig="0.993, 1" /TUlongSig="SigB" /TUlongPSig="0.995" /label="S1415" CDS complement(3635224..3635406) /gene="ywzF" /locus_tag="BSU_36669" /old_locus_tag="BSU36669" /function="18: Unknown function" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /pseudo /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /db_xref="PSEUDO:CAX52705.1" /translation="MKAGILHSLRGTVAISEVTVHDAELMAIVGFSVSWRSAPQTGLH AMLPVAEQNNGLPSGM*" gene complement(3635224..3635406) /gene="ywzF" /locus_tag="BSU_36669" /old_locus_tag="BSU36669" /pseudo S_feature complement(3635407..3635553) /Source="Nicolas_S_feature" /locus_tag="new_3769809_3769955_c" /HighExp="Etha, BT, S1, Salt, GM-0.2, GM-0.1, M9-stat, GM 5, GM 45, UNK1" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.15897800000000001" /TUshortSig="SigA, SigB" /TUshortPSig="0.993, 1" /TUlongSig="SigB" /TUlongPSig="0.995" /label="S1416" promotor_-10 complement(3635541..3635560) /Source="Nicolas_upshift_promotors" /id="U2879" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.722277722277722" /psig="0.993006993006993" /xcortree=2881 /SigmaFactorBS="tttggtcaaggtaactaaattttttaaatatTCTTTGAAtta ataggcctcttCTATATAATGATGACATAAGttgtaaacttttataacatcatttgaa g" /listShort="S1416, ywzF, S1415" /listLong="ywzE, S1414, S1413, ureA, ureB, ureC, S1412, ywnA" /label="promotor_-10" upshifts complement(3635553) /Source="Nicolas_upshifts" /id="U2879" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.722277722277722" /psig="0.993006993006993" /xcortree=2881 /SigmaFactorBS="tttggtcaaggtaactaaattttttaaatatTCTTTGAAtta ataggcctcttCTATATAATGATGACATAAGttgtaaacttttataacatcatttgaa g" /listShort="S1416, ywzF, S1415" /listLong="ywzE, S1414, S1413, ureA, ureB, ureC, S1412, ywnA" S_feature complement(3635555..3635668) /Source="Nicolas_S_feature" /locus_tag="new_3769957_3770070_c" /HighExp="Etha, Salt, M9-stat, S8, B60, B36, Sw, Gly, LoTm, C30" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigB" /TUshortPSig=1 /TUlongSig="SigB" /TUlongPSig="0.995" /label="S1417" promotor_-35 complement(3635575..3635582) /Source="Nicolas_upshift_promotors" /id="U2879" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.722277722277722" /psig="0.993006993006993" /xcortree=2881 /SigmaFactorBS="tttggtcaaggtaactaaattttttaaatatTCTTTGAAtta ataggcctcttCTATATAATGATGACATAAGttgtaaacttttataacatcatttgaa g" /listShort="S1416, ywzF, S1415" /listLong="ywzE, S1414, S1413, ureA, ureB, ureC, S1412, ywnA" /label="promotor_-35" upshifts 3635682 /Source="Nicolas_upshifts" /id="U2880" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.702297702297702" /psig="0.010989010989011" /xcortree=123 /SigmaFactorBS="tttttttgttatatttattcacatcagaaaaagcgaaaaaaa agacaagaaacatttcgtttcCTGCCtcttccgtacgattaatctttatctgaaaatt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" misc_feature 3635685..3635689 /Source="Nicolas_upshift_promotors" /id="U2880" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.702297702297702" /psig="0.010989010989011" /xcortree=123 /SigmaFactorBS="tttttttgttatatttattcacatcagaaaaagcgaaaaaaa agacaagaaacatttcgtttcCTGCCtcttccgtacgattaatctttatctgaaaatt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" CDS complement(3635702..3635890) /gene="csbD" /locus_tag="BSU_36670" /old_locus_tag="BSU36670" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:10376822, 11988534" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10376822, 11988534; Product type f: factor" /codon_start=1 /transl_table=11 /product="stress response protein" /protein_id="NP_391548.1" /db_xref="EnsemblGenomes-Gn:BSU36670" /db_xref="EnsemblGenomes-Tr:CAB15684" /db_xref="InterPro:IPR008462" /db_xref="InterPro:IPR036629" /db_xref="SubtiList:BG12478" /db_xref="UniProtKB/Swiss-Prot:P70964" /translation="MGNDSVKDKMKGGFNKAKGEVKDKVGDMADRTDMQAEGKKDKAK GEIQKDIGKAKDKFSDKD*" gene complement(3635702..3635890) /gene="csbD" /locus_tag="BSU_36670" /old_locus_tag="BSU36670" downshifts complement(3635713) /Source="Nicolas_upshifts" /id="D1899" /incds=0 /nref=69 /ntot=139 /MaxReadThrough="6.39376" /MaxDrop="6.75256" /score="21.8463823" /energy="-10.2" /TU="U2881" /idTUdmin="U2882" /TUdmin=221 /isTUend="FALSE" downshifts 3635880 /Source="Nicolas_upshifts" /id="D1900" /incds=0 /nref=15 /ntot=36 /MaxReadThrough="0.59322" /MaxDrop="5.27268" /score="-5.47050177" /energy="-8.1" /TU="NA" /idTUdmin="U2880" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(3635916..3635934) /Source="Nicolas_upshift_promotors" /id="U2881" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=222 /SigmaFactorBS="agagcgctacgaaatcgataaataacattagaaTGTTTATtg cctctcagatcGGGAAGTTAACAAGTACACacataattgagaggggagaattaacatg g" /listShort="csbD, S1417, S1416, ywzF, S1415, ywzE, S1414, S1413, ureA, ureB" /listLong="ureC, S1412, ywnA" /label="promotor_-10" upshifts complement(3635927) /Source="Nicolas_upshifts" /id="U2881" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=222 /SigmaFactorBS="agagcgctacgaaatcgataaataacattagaaTGTTTATtg cctctcagatcGGGAAGTTAACAAGTACACacataattgagaggggagaattaacatg g" /listShort="csbD, S1417, S1416, ywzF, S1415, ywzE, S1414, S1413, ureA, ureB" /listLong="ureC, S1412, ywnA" promotor_-35 complement(3635948..3635954) /Source="Nicolas_upshift_promotors" /id="U2881" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=222 /SigmaFactorBS="agagcgctacgaaatcgataaataacattagaaTGTTTATtg cctctcagatcGGGAAGTTAACAAGTACACacataattgagaggggagaattaacatg g" /listShort="csbD, S1417, S1416, ywzF, S1415, ywzE, S1414, S1413, ureA, ureB" /listLong="ureC, S1412, ywnA" /label="promotor_-35" CDS complement(3635963..3636463) /gene="ywmF" /locus_tag="BSU_36680" /old_locus_tag="BSU36680" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative integral membrane protein" /protein_id="NP_391549.2" /db_xref="EnsemblGenomes-Gn:BSU36680" /db_xref="EnsemblGenomes-Tr:CAB15685" /db_xref="GOA:P70963" /db_xref="SubtiList:BG12477" /db_xref="UniProtKB/Swiss-Prot:P70963" /translation="MHVRGNSMFGFNDMVKFLWSFLIVLPLVQIIHVSGHSFMAFIFG GKGSLDIGMGKTLLKIGPIRFRTIYFIDSFCRYGELKIDNRFSNALVYAGGCLFNLIT IFAINLLIIHSVLKPNVFFYQFVYFSTYYVFFALLPVRYSEKKSSDGLAIYKVLRYGE RYEIDK*" gene complement(3635963..3636463) /gene="ywmF" /locus_tag="BSU_36680" /old_locus_tag="BSU36680" promotor_-10 complement(3636499..3636518) /Source="Nicolas_upshift_promotors" /id="U2882" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.995004995004995" /psig="0.995004995004995" /xcortree=97 /SigmaFactorBS="tttatgcaaaaaaaggggagcatcggaaCGTTTATttccggg gagaacAGGAAAAATCGCTACAGCACtgttttttgaacaaaagccgttttgggatgca g" /listShort="ywmF" /listLong="csbD, S1417, S1416, ywzF, S1415, ywzE, S1414, S1413, ureA, ureB, ureC, S1412, ywnA" /label="promotor_-10" upshifts complement(3636506) /Source="Nicolas_upshifts" /id="U2882" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.995004995004995" /psig="0.995004995004995" /xcortree=97 /SigmaFactorBS="tttatgcaaaaaaaggggagcatcggaaCGTTTATttccggg gagaacAGGAAAAATCGCTACAGCACtgttttttgaacaaaagccgttttgggatgca g" /listShort="ywmF" /listLong="csbD, S1417, S1416, ywzF, S1415, ywzE, S1414, S1413, ureA, ureB, ureC, S1412, ywnA" promotor_-35 complement(3636532..3636538) /Source="Nicolas_upshift_promotors" /id="U2882" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.995004995004995" /psig="0.995004995004995" /xcortree=97 /SigmaFactorBS="tttatgcaaaaaaaggggagcatcggaaCGTTTATttccggg gagaacAGGAAAAATCGCTACAGCACtgttttttgaacaaaagccgttttgggatgca g" /listShort="ywmF" /listLong="csbD, S1417, S1416, ywzF, S1415, ywzE, S1414, S1413, ureA, ureB, ureC, S1412, ywnA" /label="promotor_-35" CDS complement(3636598..3637731) /gene="rapB" /locus_tag="BSU_36690" /old_locus_tag="BSU36690" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:9843420, 10629174, 12875849, 19332814, 19684115" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9843420, 10629174, 12875849, 19332814, 19684115; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="response regulator aspartate phosphatase" /protein_id="NP_391550.1" /db_xref="EnsemblGenomes-Gn:BSU36690" /db_xref="EnsemblGenomes-Tr:CAB15686" /db_xref="GOA:P70962" /db_xref="InterPro:IPR011990" /db_xref="InterPro:IPR013026" /db_xref="InterPro:IPR019734" /db_xref="SubtiList:BG11965" /db_xref="UniProtKB/Swiss-Prot:P70962" /translation="MAAYEIPSSQVGVKINKWYKHILAFQVADAVKLKEEIDLDIEQM EEDQLLLLYYQLISYRHQIMLDYVKPDLHEESQLQYRELIKTLESNQDSISGLSEYYF HLFRGMYEFEQNNYISAISFYRKAEKMLAFVEDEIERAEFHFKVAEVFYIMKQTHFSM NHAVQALETYKAHDFYRVRRIQCHFVISGNYIDYRNYEKALEHLDDAYRLALLEGQPR LIGSALYNIGNCYDDKGELDQAAEYFEKALPVFEDYQLEQLPKALFSLTRVLFKKQDS EAAIRYYEKGIAIAQKRNDFFSLAKYKFLQALYVESVNLNMIQEVFDYMEEKGLYVYI EEFALDAASYFSHREQYKEAVYFYEKAVSMREMIQRNDCLYEV*" gene complement(3636598..3637731) /gene="rapB" /locus_tag="BSU_36690" /old_locus_tag="BSU36690" downshifts complement(3636616) /Source="Nicolas_upshifts" /id="D1901" /incds=0 /nref=244 /ntot=265 /MaxReadThrough="2.8683" /MaxDrop="6.81344" /score="30.5146793" /energy="-8.1" /TU="NA" /idTUdmin="U2883" /TUdmin=0 /isTUend="TRUE" misc_feature complement(3637758..3637777) /Source="Nicolas_upshift_promotors" /id="U2883" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.994005994005994" /psig=1 /xcortree=2953 /SigmaFactorBS="cataaagaaggaatcattgtaagaaaatttaattccaaagcc atacatTATGATAAAATATAACCAATtagaaaatagaaagggttggaggggcatggcc g" /listShort="rapB" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(3637765) /Source="Nicolas_upshifts" /id="U2883" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.994005994005994" /psig=1 /xcortree=2953 /SigmaFactorBS="cataaagaaggaatcattgtaagaaaatttaattccaaagcc atacatTATGATAAAATATAACCAATtagaaaatagaaagggttggaggggcatggcc g" /listShort="rapB" /GFF_Attribute="listLong" promotor_-10 complement(3637828..3637846) /Source="Nicolas_upshift_promotors" /id="U2884" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp="0.99100899100899" /psig="0.99100899100899" /xcortree=2786 /SigmaFactorBS="tcggcactgtccggtaagcttttttattagaatccgaGTGCA AAAaatacgtagaaaaACCGAAATATATAAGGATAggcataaagaaggaatcattgta a" /listShort="rapB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3637844) /Source="Nicolas_upshifts" /id="U2884" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp="0.99100899100899" /psig="0.99100899100899" /xcortree=2786 /SigmaFactorBS="tcggcactgtccggtaagcttttttattagaatccgaGTGCA AAAaatacgtagaaaaACCGAAATATATAAGGATAggcataaagaaggaatcattgta a" /listShort="rapB" /GFF_Attribute="listLong" promotor_-35 complement(3637860..3637867) /Source="Nicolas_upshift_promotors" /id="U2884" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp="0.99100899100899" /psig="0.99100899100899" /xcortree=2786 /SigmaFactorBS="tcggcactgtccggtaagcttttttattagaatccgaGTGCA AAAaatacgtagaaaaACCGAAATATATAAGGATAggcataaagaaggaatcattgta a" /listShort="rapB" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3637923..3638948) /gene="moaA" /locus_tag="BSU_36700" /old_locus_tag="BSU36700" /EC_number="4.1.99.22" /function="16.10: Respire" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2b: Function from indirect experimental evidences (e.g. phenotypes); PubMedId: 2170340, 7860592, 16632608, 19566093, 23286307, 25896388, 25941396, 26575208; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="GTP 3',8-cyclase" /protein_id="NP_391551.1" /db_xref="EnsemblGenomes-Gn:BSU36700" /db_xref="EnsemblGenomes-Tr:CAB15687" /db_xref="GOA:P39757" /db_xref="InterPro:IPR000385" /db_xref="InterPro:IPR006638" /db_xref="InterPro:IPR007197" /db_xref="InterPro:IPR010505" /db_xref="InterPro:IPR013483" /db_xref="InterPro:IPR013785" /db_xref="InterPro:IPR034395" /db_xref="InterPro:IPR034481" /db_xref="SubtiList:BG10980" /db_xref="UniProtKB/Swiss-Prot:P39757" /translation="MITESRQMLDKRNRPLRDLRISVTDRCNFRCTYCMPAELFGPDY PFLKKEELLSFEELERLATLFVTRFGVEKIRLTGGEPLMRKDMPELIKKLARIPGIRD IAMTTNGSLLPVYAKRLKEAGLKRVTISLDSLEDERFKKINGRGVSVSKVLEGIEAAK QAGLGVKINMVVQKGVNEKDILPMARYFKEKGHILRFIEFMDVGNTNQWEKKDVMTKA EIIDLINKHMPVEPIAPNYIGEVASRFRYLDGSGEIGVISSVSDAFCGSCNRARLSAR GELFTCLFASSGFDLRAPVRQELSDDELSEMIGTVWKNRIDQYSVDRTLSKASGKKKV EMSYIGG*" gene complement(3637923..3638948) /gene="moaA" /locus_tag="BSU_36700" /old_locus_tag="BSU36700" downshifts complement(3637936) /Source="Nicolas_upshifts" /id="D1902" /incds=0 /nref=23 /ntot=147 /MaxReadThrough="3.05546" /MaxDrop="3.66108" /score="13.625744" /energy="-10.8" /TU="NA" /idTUdmin="U2885" /TUdmin=0 /isTUend="TRUE" CDS complement(3638964..3639752) /gene="fdhD" /locus_tag="BSU_36710" /old_locus_tag="BSU36710" /function="16.11: Scavenge (Catabolism)" /function="16.10: Respire" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 2170340, 7860592, 19114526, 20011599, 22194618; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="protein sulfur transferase involved in molybdenum cofactor synthesis" /protein_id="NP_391552.1" /db_xref="EnsemblGenomes-Gn:BSU36710" /db_xref="EnsemblGenomes-Tr:CAB15688" /db_xref="GOA:P39756" /db_xref="InterPro:IPR003786" /db_xref="InterPro:IPR016193" /db_xref="SubtiList:BG10979" /db_xref="UniProtKB/Swiss-Prot:P39756" /translation="MNDKVTAVRDVWRYEQGEISKVEDRMVTEFPLTVILNGSEFVTL VCTPEHIEELVIGFLASEGVIRFQKEIKRFTIDESLGFVYVDLVHPETLDQKDYTKRV IGSCCGKGRHFYFQQDVKTAKTAVSQIKISPEACLALMKDMQQGSGTFQDTGGVHNAA LCDTEKLLLMRTDIGRHNALDKLYGHCLLNGMSVRDKLIVFSGRISSEVLLKAAKIGV SIVISKSAPTELAIQMAEELNITAIGFVRNGSFNVYTHPERIRE*" gene complement(3638964..3639752) /gene="fdhD" /locus_tag="BSU_36710" /old_locus_tag="BSU36710" promotor_-10 complement(3639778..3639797) /Source="Nicolas_upshift_promotors" /id="U2885" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.965034965034965" /psig="0.986013986013986" /xcortree=1964 /SigmaFactorBS="tatagagggctctttttgtgtctcagAATTCGACaaaatccg aggagTGTGAAAAAATATAAAGGCAggaacattgcggaggggaagagacattgaacga t" /listShort="fdhD, moaA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3639784) /Source="Nicolas_upshifts" /id="U2885" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.965034965034965" /psig="0.986013986013986" /xcortree=1964 /SigmaFactorBS="tatagagggctctttttgtgtctcagAATTCGACaaaatccg aggagTGTGAAAAAATATAAAGGCAggaacattgcggaggggaagagacattgaacga t" /listShort="fdhD, moaA" /GFF_Attribute="listLong" S_feature complement(3639786..3639997) /Source="Nicolas_S_feature" /locus_tag="new_3774188_3774399_c" /HighExp="Etha, Sw, Salt, Heat, S8, Gly, S6, S7, BC, S5" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.16930300000000001" /TUshortSig="SigB" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1418" promotor_-35 complement(3639811..3639818) /Source="Nicolas_upshift_promotors" /id="U2885" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.965034965034965" /psig="0.986013986013986" /xcortree=1964 /SigmaFactorBS="tatagagggctctttttgtgtctcagAATTCGACaaaatccg aggagTGTGAAAAAATATAAAGGCAggaacattgcggaggggaagagacattgaacga t" /listShort="fdhD, moaA" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3639998..3640159) /gene="ywmE" /locus_tag="BSU_36720" /old_locus_tag="BSU36720" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_391553.1" /db_xref="EnsemblGenomes-Gn:BSU36720" /db_xref="EnsemblGenomes-Tr:CAB15689" /db_xref="GOA:P70966" /db_xref="SubtiList:BG12476" /db_xref="UniProtKB/Swiss-Prot:P70966" /translation="MKLFGMIFLIATVAFILLGVLLKLAAFFFVSILTLIAAIVLFTV LKKNQHNQT*" gene complement(3639998..3640159) /gene="ywmE" /locus_tag="BSU_36720" /old_locus_tag="BSU36720" promotor_-10 complement(3640172..3640190) /Source="Nicolas_upshift_promotors" /id="U2886" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=166 /SigmaFactorBS="ggaacctaaagatcaggcgctcccccaggcgccttttttatt GGTTTAAaaacagtttgggcGGGAATGATACCCTAAAAAggggttgaacatatgaaat t" /listShort="ywmE, S1418" /listLong="fdhD, moaA" /label="promotor_-10" upshifts complement(3640192) /Source="Nicolas_upshifts" /id="U2886" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=166 /SigmaFactorBS="ggaacctaaagatcaggcgctcccccaggcgccttttttatt GGTTTAAaaacagtttgggcGGGAATGATACCCTAAAAAggggttgaacatatgaaat t" /listShort="ywmE, S1418" /listLong="fdhD, moaA" promotor_-35 complement(3640204..3640210) /Source="Nicolas_upshift_promotors" /id="U2886" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=166 /SigmaFactorBS="ggaacctaaagatcaggcgctcccccaggcgccttttttatt GGTTTAAaaacagtttgggcGGGAATGATACCCTAAAAAggggttgaacatatgaaat t" /listShort="ywmE, S1418" /listLong="fdhD, moaA" /label="promotor_-35" CDS complement(3640253..3640927) /gene="ywmD" /locus_tag="BSU_36730" /old_locus_tag="BSU36730" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type f: factor" /codon_start=1 /transl_table=11 /product="putative exported protein" /protein_id="NP_391554.1" /db_xref="EnsemblGenomes-Gn:BSU36730" /db_xref="EnsemblGenomes-Tr:CAB15690" /db_xref="InterPro:IPR002035" /db_xref="InterPro:IPR036465" /db_xref="SubtiList:BG12475" /db_xref="UniProtKB/Swiss-Prot:P70961" /translation="MKKLLAAGIIGLLTVSIASPSFAAEKQADTNVAVLFDGSGSMVQ KTGGERKIDIAKKSVKSFAELLPKDTNLMLRVFGHAGNNKLSGKALSCSTTETIYGLH PYEGSLFDNSLSELKPTGWTPIAKALADTRKEFEAFDADGKNVVYLITDGEETCGGDP AAEIEKLRASNVDTIVNIIGFNFDVKGNEEMKQAAVAGGGEYISANSADEFEQAWEKE AQKFTE*" gene complement(3640253..3640927) /gene="ywmD" /locus_tag="BSU_36730" /old_locus_tag="BSU36730" downshifts complement(3640268) /Source="Nicolas_upshifts" /id="D1903" /incds=0 /nref=16 /ntot=88 /MaxReadThrough="0.76221" /MaxDrop="4.19611" /score="25.2461653" /energy="-9.6" /TU="NA" /idTUdmin="U2886" /TUdmin="-462" /isTUend="FALSE" CDS complement(3640980..3641120) /locus_tag="BSU_36739" /old_locus_tag="BSU36739" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_009514009.1" /translation="MITQAVYAFWAEMAKNERHFKRFWTDRESSTKGSMSYIFLHFRI LA*" gene complement(3640980..3641120) /locus_tag="BSU_36739" /old_locus_tag="BSU36739" CDS complement(3641251..3641934) /gene="ywmC" /locus_tag="BSU_36740" /old_locus_tag="BSU36740" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type f: factor" /codon_start=1 /transl_table=11 /product="putative exported protein" /protein_id="NP_391555.1" /db_xref="EnsemblGenomes-Gn:BSU36740" /db_xref="EnsemblGenomes-Tr:CAB15691" /db_xref="InterPro:IPR002035" /db_xref="InterPro:IPR036465" /db_xref="SubtiList:BG12474" /db_xref="UniProtKB/Swiss-Prot:P70960" /translation="MKKRFSLIMMTGLLFGLTSPAFAAEKTETEAKAPANVAVLLDAS GSMAKRIDGVSKFNSAKKEISKFASSLPEGTQVKMSVFGSEGNNKNSGKVQSCEAIRN VYGFQSFNEQSFLNSLNTIGPTGWTPIAKALNEAKSSFDQLDAKGEKVVYLLTDGEET CGGNPIKTAKELQKDNITVNVIGFDYKEGYKGQLNAIAKVGGGEYFPAYTQKDVEKIF TQQSLMLSK*" gene complement(3641251..3641934) /gene="ywmC" /locus_tag="BSU_36740" /old_locus_tag="BSU36740" promotor_-35 3642311..3642315 /Source="Nicolas_upshift_promotors" /id="U2887" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.687312687312687" /psig="0.687312687312687" /xcortree=1394 /SigmaFactorBS="aacagaaaaagacgcccaatgagCGTCTttttctactttttc GCCATATATTTATTCAAAAAcgcatctgcctcagaaatttgtgtgccttggtaatagt a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3642320..3643351) /gene="spoIID" /locus_tag="BSU_36750" /old_locus_tag="BSU36750" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:15752199, 16959571, 17376078, 27226615" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15752199, 16959571, 17376078, 27226615; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="lytic transglycosylase; autolysin required for complete dissolution of the asymmetric septum (stage II sporulation)" /protein_id="NP_391556.1" /db_xref="EnsemblGenomes-Gn:BSU36750" /db_xref="EnsemblGenomes-Tr:CAB15692" /db_xref="GOA:P07372" /db_xref="InterPro:IPR013486" /db_xref="InterPro:IPR013693" /db_xref="InterPro:IPR014225" /db_xref="SubtiList:BG10766" /db_xref="UniProtKB/Swiss-Prot:P07372" /translation="MKQFAITLSVLCALILLVPTLLVIPFQHNKEAGASVESEKTAVS TKPASKGAETLKASPVSIPVYRTANQSVENIPLEEYVIGVVASEMPATFKPEALKAQA LAARTFIVRLMVSNSAVEAPKGSLVDDTQMFQVYKSKAELKKQWGTSYETKLKKITDA VASTQGKILTYNNQPIEASFFSTSNGYTENAEAYWTSAIPYLKSVKSPWDKKSPKYKA TKTFTAAEFQQKLGVKLDGSSAVGKITGETPGHQVATAVINGKTLKGRDIREKLGLNS ADFEWKRNGDTITVTTRGFGHGVGMSQYGANFMAKEGKTVDDIVKYYYQGTQISEADA FLNKYMAKK*" gene complement(3642320..3643351) /gene="spoIID" /locus_tag="BSU_36750" /old_locus_tag="BSU36750" promotor_-10 3642330..3642349 /Source="Nicolas_upshift_promotors" /id="U2887" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.687312687312687" /psig="0.687312687312687" /xcortree=1394 /SigmaFactorBS="aacagaaaaagacgcccaatgagCGTCTttttctactttttc GCCATATATTTATTCAAAAAcgcatctgcctcagaaatttgtgtgccttggtaatagt a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" downshifts complement(3642336) /Source="Nicolas_upshifts" /id="D1904" /incds=0 /nref=56 /ntot=156 /MaxReadThrough="0.87893" /MaxDrop="6.31542" /score="12.1351765" /energy="-8.7" /TU="NA" /idTUdmin="U2888" /TUdmin=0 /isTUend="TRUE" upshifts 3642348 /Source="Nicolas_upshifts" /id="U2887" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.687312687312687" /psig="0.687312687312687" /xcortree=1394 /SigmaFactorBS="aacagaaaaagacgcccaatgagCGTCTttttctactttttc GCCATATATTTATTCAAAAAcgcatctgcctcagaaatttgtgtgccttggtaatagt a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 complement(3643379..3643397) /Source="Nicolas_upshift_promotors" /id="U2888" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=978 /SigmaFactorBS="taaatgacaaataaagtttctgtccaaaacgagaGTCATAtt agcttgtccctgcCCATAGACTAGACTAGAGTcgaatcccgagcaggaggcagctgaa t" /listShort="spoIID" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3643392) /Source="Nicolas_upshifts" /id="U2888" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=978 /SigmaFactorBS="taaatgacaaataaagtttctgtccaaaacgagaGTCATAtt agcttgtccctgcCCATAGACTAGACTAGAGTcgaatcccgagcaggaggcagctgaa t" /listShort="spoIID" /GFF_Attribute="listLong" S_feature complement(3643394..3643511) /Source="Nicolas_S_feature" /locus_tag="new_3777796_3777913_c" /HighExp="S8, M40t90, M9-stat, B36, LBGtran, G180, H2O2, M0t90, BT, T1.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigK, SigI, SigWXY, SigA" /TUshortPSig="0.947, 0.999, 1, 0.973" /TUlongSig="SigL, SigA, SigA" /TUlongPSig="0.722, 0.998, 1" /label="S1419" promotor_-35 complement(3643413..3643418) /Source="Nicolas_upshift_promotors" /id="U2888" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=978 /SigmaFactorBS="taaatgacaaataaagtttctgtccaaaacgagaGTCATAtt agcttgtccctgcCCATAGACTAGACTAGAGTcgaatcccgagcaggaggcagctgaa t" /listShort="spoIID" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 3643453..3643458 /Source="Nicolas_upshift_promotors" /id="U2889" /multdbtbs="SigF" /comp="M3" /sig="SigEF" /pcomp="0.971028971028971" /psig="0.971028971028971" /xcortree=1072 /SigmaFactorBS="taatatgactctcgttttggacagaaactttatttgtcattt aCGTATTcttttttgctattttGCGCATAATGATGATAATAcacaaaaaataaaaaac c" /listShort="S1420, ywmA" /GFF_Attribute="listLong" /label="promotor_-35" S_feature 3643470..3646130 /Source="Nicolas_S_feature" /locus_tag="new_3777872_3780532" /HighExp="S8, S6, S7, S4, S3, C30, S5, T5.0H, T3.30H, BT" /AntisenseName="murAA" /AntisenseCor="5.8371061376981899E-2" /AntisenseRegPval="-0.5" /CDS_PredictionProba="NA" /TUshortSig="SigEF" /TUshortPSig="0.971" /TUlongSig="NA" /TUlongPSig="NA" /label="S1420" upshifts 3643470 /Source="Nicolas_upshifts" /id="U2889" /multdbtbs="SigF" /comp="M3" /sig="SigEF" /pcomp="0.971028971028971" /psig="0.971028971028971" /xcortree=1072 /SigmaFactorBS="taatatgactctcgttttggacagaaactttatttgtcattt aCGTATTcttttttgctattttGCGCATAATGATGATAATAcacaaaaaataaaaaac c" /listShort="S1420, ywmA" /GFF_Attribute="listLong" promotor_-10 3643474..3643492 /Source="Nicolas_upshift_promotors" /id="U2889" /multdbtbs="SigF" /comp="M3" /sig="SigEF" /pcomp="0.971028971028971" /psig="0.971028971028971" /xcortree=1072 /SigmaFactorBS="taatatgactctcgttttggacagaaactttatttgtcattt aCGTATTcttttttgctattttGCGCATAATGATGATAATAcacaaaaaataaaaaac c" /listShort="S1420, ywmA" /GFF_Attribute="listLong" /label="promotor_-10" CDS complement(3643547..3644857) /gene="murAA" /locus_tag="BSU_36760" /old_locus_tag="BSU36760" /EC_number="2.5.1.7" /function="16.2: Construct biomass (Anabolism)" /function="16.13: Shape" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:12682299, 14763982, 17714441" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12682299, 14763982, 17714441; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="UDP-N-acetylglucosamine 1-carboxyvinyltransferase" /protein_id="NP_391557.1" /db_xref="EnsemblGenomes-Gn:BSU36760" /db_xref="EnsemblGenomes-Tr:CAB15693" /db_xref="GOA:P70965" /db_xref="InterPro:IPR001986" /db_xref="InterPro:IPR005750" /db_xref="InterPro:IPR013792" /db_xref="InterPro:IPR036968" /db_xref="SubtiList:BG11955" /db_xref="UniProtKB/Swiss-Prot:P70965" /translation="MEKIIVRGGQKLNGTVKVEGAKNAVLPVIAASLLASEEKSVICD VPTLSDVYTINEVLRHLGADVHFENNEVTVNASYALQTEAPFEYVRKMRASVLVMGPL LARTGHARVALPGGCAIGSRPIDQHLKGFEAMGAEIKVGNGFIEAEVKGRLQGAKIYL DFPSVGATENLIMAAALAEGTTTLENVAKEPEIVDLANYINGMGGKIRGAGTGTIKIE GVEKLHGVKHHIIPDRIEAGTFMVAAAITEGNVLVKGAVPEHLTSLIAKMEEMGVTIK DEGEGLRVIGPKELKPIDIKTMPHPGFPTDMQSQMMALLLRASGTSMITETVFENRFM HAEEFRRMNGDIKIEGRSVIINGPVQLQGAEVAATDLRAGAALILAGLVAEGHTRVTE LKHLDRGYVDFHQKLAALGADIERVNDESASEQENKEVVSDLNA*" gene complement(3643547..3644857) /gene="murAA" /locus_tag="BSU_36760" /old_locus_tag="BSU36760" downshifts complement(3643556) /Source="Nicolas_upshifts" /id="D1905" /incds=0 /nref=171 /ntot=256 /MaxReadThrough="5.3301" /MaxDrop="5.5423" /score="31.3825723" /energy="-11.8" /TU="U2890,U2891,U2892,U2894" /idTUdmin="U2890" /TUdmin="-98" /isTUend="FALSE" promotor_-10 complement(3644881..3644900) /Source="Nicolas_upshift_promotors" /id="U2890" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.947052947052947" /psig="0.947052947052947" /xcortree=752 /SigmaFactorBS="aatgggcggaaaacataccgttacgGTTGGCACACcaatcgt tacgacTGAATATTAATATAGAGAATttagggacgcggaggggaataccttggaaaaa a" /listShort="murAA, S1419" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3644888) /Source="Nicolas_upshifts" /id="U2890" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.947052947052947" /psig="0.947052947052947" /xcortree=752 /SigmaFactorBS="aatgggcggaaaacataccgttacgGTTGGCACACcaatcgt tacgacTGAATATTAATATAGAGAATttagggacgcggaggggaataccttggaaaaa a" /listShort="murAA, S1419" /GFF_Attribute="listLong" CDS complement(3644891..3645631) /gene="ywmB" /locus_tag="BSU_36770" /old_locus_tag="BSU36770" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_391558.1" /db_xref="EnsemblGenomes-Gn:BSU36770" /db_xref="EnsemblGenomes-Tr:CAB15694" /db_xref="InterPro:IPR014794" /db_xref="InterPro:IPR036209" /db_xref="PDB:2FPN" /db_xref="SubtiList:BG12473" /db_xref="UniProtKB/Swiss-Prot:O32277" /translation="MKKKQVSHAIIISVMLSFVIAVFHTIHASELTPLAQMAEGMERQ DVSIDKWTLHAKQNLSLTEKEFYQKVQRLKQEYRQYDWVIAREDKMIKAIGTYTDKKN RTSFRLQLVTTLKKHNPTSYLLYEQMSLETPDSWNDTYEQFERETLGIFQEKVVIFTC LNGHLDDNMNIVLQKKANQLLNEFQARSVEHVVEPNFVSISAFTDEWEEYIMTSKHKM NLQIALRSAGMGGKHTVTVGTPIVTTEY*" gene complement(3644891..3645631) /gene="ywmB" /locus_tag="BSU_36770" /old_locus_tag="BSU36770" promotor_-35 complement(3644914..3644923) /Source="Nicolas_upshift_promotors" /id="U2890" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.947052947052947" /psig="0.947052947052947" /xcortree=752 /SigmaFactorBS="aatgggcggaaaacataccgttacgGTTGGCACACcaatcgt tacgacTGAATATTAATATAGAGAATttagggacgcggaggggaataccttggaaaaa a" /listShort="murAA, S1419" /GFF_Attribute="listLong" /label="promotor_-35" upshifts complement(3645262) /Source="Nicolas_upshifts" /id="U2891" /multdbtbs="-" /comp="M2" /sig="SigI" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1770 /SigmaFactorBS="acttcttttagactgcagcttgtcacaaCCCTCAAAAaacac aatccaacTTCGTATTTattatatgagcaaatgagtctagagacaccggatagctgga a" /listShort="murAA, S1419, spoIID" /GFF_Attribute="listLong" promotor_-10 complement(3645264..3645272) /Source="Nicolas_upshift_promotors" /id="U2891" /multdbtbs="-" /comp="M2" /sig="SigI" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1770 /SigmaFactorBS="acttcttttagactgcagcttgtcacaaCCCTCAAAAaacac aatccaacTTCGTATTTattatatgagcaaatgagtctagagacaccggatagctgga a" /listShort="murAA, S1419, spoIID" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 complement(3645286..3645294) /Source="Nicolas_upshift_promotors" /id="U2891" /multdbtbs="-" /comp="M2" /sig="SigI" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1770 /SigmaFactorBS="acttcttttagactgcagcttgtcacaaCCCTCAAAAaacac aatccaacTTCGTATTTattatatgagcaaatgagtctagagacaccggatagctgga a" /listShort="murAA, S1419, spoIID" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(3645386..3645401) /Source="Nicolas_upshift_promotors" /id="U2892" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=2506 /SigmaFactorBS="tcactgaccgaaaaagaattttatcaaaaagTGCAACGTTTa aaacaagagtaTCGTCAATATGATTGGgtgattgcacgggaagataaaatgataaagg c" /listShort="murAA, S1419, spoIID" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3645394) /Source="Nicolas_upshifts" /id="U2892" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=2506 /SigmaFactorBS="tcactgaccgaaaaagaattttatcaaaaagTGCAACGTTTa aaacaagagtaTCGTCAATATGATTGGgtgattgcacgggaagataaaatgataaagg c" /listShort="murAA, S1419, spoIID" /GFF_Attribute="listLong" promotor_-35 complement(3645414..3645423) /Source="Nicolas_upshift_promotors" /id="U2892" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=2506 /SigmaFactorBS="tcactgaccgaaaaagaattttatcaaaaagTGCAACGTTTa aaacaagagtaTCGTCAATATGATTGGgtgattgcacgggaagataaaatgataaagg c" /listShort="murAA, S1419, spoIID" /GFF_Attribute="listLong" /label="promotor_-35" S_feature complement(3645632..3645759) /Source="Nicolas_S_feature" /locus_tag="new_3780034_3780161_c" /HighExp="UNK1, S2, Lbexp, MG 60, MG 15, M9-tran, M/G, G135, MG 5, LBGexp" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.973" /TUlongSig="SigL, SigA, SigA" /TUlongPSig="0.722, 0.998, 1" /label="S1421" CDS complement(3645760..3645990) /gene="ywzB" /locus_tag="BSU_36780" /old_locus_tag="BSU36780" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_391559.1" /db_xref="EnsemblGenomes-Gn:BSU36780" /db_xref="EnsemblGenomes-Tr:CAB15695" /db_xref="GOA:O32278" /db_xref="InterPro:IPR009526" /db_xref="SubtiList:BG14163" /db_xref="UniProtKB/Swiss-Prot:O32278" /translation="MSVLGQQAAIGIVVHLIFIAVTWWALQAVNIDPLIKKGKVVQAR LLMILLTIAIGTAVANFFLDYLNYSQQLPYLF*" gene complement(3645760..3645990) /gene="ywzB" /locus_tag="BSU_36780" /old_locus_tag="BSU36780" S_feature complement(3645991..3646253) /Source="Nicolas_S_feature" /locus_tag="new_3780393_3780655_c" /HighExp="UNK1, S2, Lbexp, MG 5, M9-tran, M/G, MG 15, MG 60, GM 15, MG t5" /AntisenseName="ywmA" /AntisenseCor="-0.24099136307237601" /AntisenseRegPval="-4.2" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.973" /TUlongSig="SigL, SigA, SigA" /TUlongPSig="0.722, 0.998, 1" /label="S1422" misc_feature 3646126..3646145 /Source="Nicolas_upshift_promotors" /id="U2893" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.828171828171828" /psig=1 /xcortree=411 /SigmaFactorBS="cggaataatcagccaaatctagggctaatccccgcttaaagt gcgattcttttaCATGGTATACTTTATTGGAAaggagctggcaaatgtgaatcattct t" /listShort="ywmA" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 3646132 /Source="Nicolas_upshifts" /id="U2893" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.828171828171828" /psig=1 /xcortree=411 /SigmaFactorBS="cggaataatcagccaaatctagggctaatccccgcttaaagt gcgattcttttaCATGGTATACTTTATTGGAAaggagctggcaaatgtgaatcattct t" /listShort="ywmA" /GFF_Attribute="listLong" CDS 3646160..3646633 /gene="ywmA" /locus_tag="BSU_36790" /old_locus_tag="BSU36790" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_391560.1" /db_xref="EnsemblGenomes-Gn:BSU36790" /db_xref="EnsemblGenomes-Tr:CAB15696" /db_xref="SubtiList:BG12472" /db_xref="UniProtKB/Swiss-Prot:P70958" /translation="MNHSFFQPEKQYGEDLPIFDQEWEAIAFYYDYRQSQIEELNELC QFFNISLTYTRESLEELENLYFQSIQELLLADWNLPIEEFEKMISVYLIDCVIARHED AEWVVKPYPYKDGAYTLGFRRHRKSWHTMNACDGLYLRPKEDRPLLSLFDSLVRS*" gene 3646160..3646633 /gene="ywmA" /locus_tag="BSU_36790" /old_locus_tag="BSU36790" promotor_-10 complement(3646237..3646256) /Source="Nicolas_upshift_promotors" /id="U2894" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.843156843156843" /psig="0.973026973026973" /xcortree=2712 /SigmaFactorBS="taagagaaatgttaaaaaactgacacaattcattcagttCTT CaatctgtgactgtcTATAATCATAATAGAATGCAattgcttcccattcctgatcaaa a" /listShort="S1422, ywzB, S1421, ywmB, murAA, S1419" /listLong="spoIID" /label="promotor_-10" upshifts complement(3646253) /Source="Nicolas_upshifts" /id="U2894" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.843156843156843" /psig="0.973026973026973" /xcortree=2712 /SigmaFactorBS="taagagaaatgttaaaaaactgacacaattcattcagttCTT CaatctgtgactgtcTATAATCATAATAGAATGCAattgcttcccattcctgatcaaa a" /listShort="S1422, ywzB, S1421, ywmB, murAA, S1419" /listLong="spoIID" S_feature complement(3646255..3646638) /Source="Nicolas_S_feature" /locus_tag="new_3780657_3781040_c" /HighExp="G135, G180, G150, H2O2, Oxctl, Paraq, Cold, M9-stat, C30, S0" /AntisenseName="ywmA" /AntisenseCor="-1.9581968147303098E-2" /AntisenseRegPval="-0.1" /CDS_PredictionProba="NA" /TUshortSig="SigL, SigA" /TUshortPSig="0.722, 0.998" /TUlongSig="SigA" /TUlongPSig=1 /label="S1423" promotor_-35 complement(3646271..3646274) /Source="Nicolas_upshift_promotors" /id="U2894" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.843156843156843" /psig="0.973026973026973" /xcortree=2712 /SigmaFactorBS="taagagaaatgttaaaaaactgacacaattcattcagttCTT CaatctgtgactgtcTATAATCATAATAGAATGCAattgcttcccattcctgatcaaa a" /listShort="S1422, ywzB, S1421, ywmB, murAA, S1419" /listLong="spoIID" /label="promotor_-35" CDS complement(3646667..3647065) /gene="atpC" /locus_tag="BSU_36800" /old_locus_tag="BSU36800" /EC_number="3.6.3.14" /function="16.7: Manage energy" /experiment="publication(s) with functional evidences, PMID:8021203, 12837747, 15347741, 22720735, 23967352" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8021203, 12837747, 15347741, 22720735, 23967352; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="ATP synthase (subunit epsilon, F1 subunit)" /protein_id="NP_391561.1" /db_xref="EnsemblGenomes-Gn:BSU36800" /db_xref="EnsemblGenomes-Tr:CAB15697" /db_xref="GOA:P37812" /db_xref="InterPro:IPR001469" /db_xref="InterPro:IPR020546" /db_xref="InterPro:IPR020547" /db_xref="InterPro:IPR036771" /db_xref="InterPro:IPR036794" /db_xref="SubtiList:BG10822" /db_xref="UniProtKB/Swiss-Prot:P37812" /translation="MKTVKVNIVTPDGPVYDADIEMVSVRAESGDLGILPGHIPTVAP LKIGAVRLKKDGQTEMVAVSGGFVEVRPDHVTILAQAAETAEGIDKERAEAARQRAQE RLNSQSDDTDIRRAELALQRALNRLDVAGK*" gene complement(3646667..3647065) /gene="atpC" /locus_tag="BSU_36800" /old_locus_tag="BSU36800" downshifts complement(3646683) /Source="Nicolas_upshifts" /id="D1906" /incds=0 /nref=283 /ntot=320 /MaxReadThrough="4.15968" /MaxDrop="7.84101" /score="22.7623678" /energy="-10.8" /TU="U2897,U2899" /idTUdmin="U2895" /TUdmin=9 /isTUend="TRUE" promotor_-10 complement(3647057..3647075) /Source="Nicolas_upshift_promotors" /id="U2895" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.994005994005994" /psig="0.994005994005994" /xcortree=107 /SigmaFactorBS="ttgttgagaaagcaaaagaaatgggtgtagaAGTTTAAtctg gtcctaggaGGGTAAAAGCATGAAGACCgttaaagtcaatatcgttactcccgacggc c" /listShort="atpC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3647066) /Source="Nicolas_upshifts" /id="U2895" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.994005994005994" /psig="0.994005994005994" /xcortree=107 /SigmaFactorBS="ttgttgagaaagcaaaagaaatgggtgtagaAGTTTAAtctg gtcctaggaGGGTAAAAGCATGAAGACCgttaaagtcaatatcgttactcccgacggc c" /listShort="atpC" /GFF_Attribute="listLong" promotor_-35 complement(3647089..3647095) /Source="Nicolas_upshift_promotors" /id="U2895" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.994005994005994" /psig="0.994005994005994" /xcortree=107 /SigmaFactorBS="ttgttgagaaagcaaaagaaatgggtgtagaAGTTTAAtctg gtcctaggaGGGTAAAAGCATGAAGACCgttaaagtcaatatcgttactcccgacggc c" /listShort="atpC" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3647089..3648510) /gene="atpD" /locus_tag="BSU_36810" /old_locus_tag="BSU36810" /EC_number="3.6.3.14" /function="16.10: Respire" /experiment="publication(s) with functional evidences, PMID:8021203, 15347741, 18174126, 22790590" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8021203, 15347741, 18174126, 22790590; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="ATP synthase (subunit beta, component F1)" /protein_id="NP_391562.1" /db_xref="EnsemblGenomes-Gn:BSU36810" /db_xref="EnsemblGenomes-Tr:CAB15698" /db_xref="GOA:P37809" /db_xref="InterPro:IPR000194" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR004100" /db_xref="InterPro:IPR005722" /db_xref="InterPro:IPR020003" /db_xref="InterPro:IPR024034" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR036121" /db_xref="SubtiList:BG10821" /db_xref="UniProtKB/Swiss-Prot:P37809" /translation="MKKGRVSQVLGPVVDVRFEDGHLPEIYNAIKISQPAASENEVGI DLTLEVALHLGDDTVRTIAMASTDGVQRGMEAVDTGAPISVPVGDVTLGRVFNVLGEN IDLNEPVPADAKKDPIHRQAPSFDQLSTEVEILETGIKVVDLLAPYIKGGKIGLFGGA GVGKTVLIQELINNIAQEHGGISVFAGVGERTREGNDLFYEMSDSGVINKTAMVFGQM NEPPGARMRVALTGLTMAEHFRDVQGQDVLFFIDNIFRFTQAGSEVSALLGRMPSAVG YQPTLATEMGQLQERITSTNVGSVTSIQAIYVPADDYTDPAPATTFAHLDATTNLERK LTEMGIYPAVDPLASTSRALAPEIVGEEHYAVAREVQSTLQRYKELQDIIAILGMDEL GEEDKLVVHRARRIQFFLSQNFHVAEQFTGQKGSYVPVKETVQGFKEILAGKYDHLPE DAFRLVGRIEEVVEKAKEMGVEV*" gene complement(3647089..3648510) /gene="atpD" /locus_tag="BSU_36810" /old_locus_tag="BSU36810" CDS complement(3648536..3649399) /gene="atpG" /locus_tag="BSU_36820" /old_locus_tag="BSU36820" /EC_number="3.6.3.14" /function="16.10: Respire" /experiment="publication(s) with functional evidences, PMID:8021203, 15347741, 18174126, 22790590" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8021203, 15347741, 18174126, 22790590; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="ATP synthase (subunit gamma, component F1)" /protein_id="NP_391563.1" /db_xref="EnsemblGenomes-Gn:BSU36820" /db_xref="EnsemblGenomes-Tr:CAB15699" /db_xref="GOA:P37810" /db_xref="InterPro:IPR000131" /db_xref="InterPro:IPR023632" /db_xref="InterPro:IPR035968" /db_xref="SubtiList:BG10820" /db_xref="UniProtKB/Swiss-Prot:P37810" /translation="MASLRDIKSRITSTKKTSQITKAMQMVSAAKLNRAENNAKSFVP YMDKIQEVVSNVGRVSGNVKHPMLLSREVKKTAYLVITSDRGLAGAFNSSVLRSAYQA MQERHQSKDEYAVIAIGRVGRDFFKKREIPIISELTGLGDEVTFTEIKDLARQTIQMF IDGAFDELHLVYNHFVSAITQEVTEKKLLPLSDLGSGGGKRTASYEFEPSEEEVLEVL LPQYAESLIFGALLDSKASEHAARMTAMKNATDNAKELIDSLSLSYNRARQAAITQEI TEIVGGAAALE*" gene complement(3648536..3649399) /gene="atpG" /locus_tag="BSU_36820" /old_locus_tag="BSU36820" S_feature complement(3649400..3649475) /Source="Nicolas_S_feature" /locus_tag="new_3783802_3783877_c" /HighExp="S0, S2, MG-0.2, MG-0.1, Mal, G150, BI, M0t45, G180, MG 5" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigL, SigA" /TUshortPSig="0.722, 0.998" /TUlongSig="SigA" /TUlongPSig=1 /label="S1424" CDS complement(3649476..3650984) /gene="atpA" /locus_tag="BSU_36830" /old_locus_tag="BSU36830" /EC_number="3.6.3.14" /function="16.10: Respire" /experiment="publication(s) with functional evidences, PMID:8021203, 15347741, 1655755" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8021203, 15347741, 1655755; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="ATP synthase (subunit alpha, component F1)" /protein_id="NP_391564.1" /db_xref="EnsemblGenomes-Gn:BSU36830" /db_xref="EnsemblGenomes-Tr:CAB15700" /db_xref="GOA:P37808" /db_xref="InterPro:IPR000194" /db_xref="InterPro:IPR000793" /db_xref="InterPro:IPR004100" /db_xref="InterPro:IPR005294" /db_xref="InterPro:IPR020003" /db_xref="InterPro:IPR023366" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR033732" /db_xref="InterPro:IPR036121" /db_xref="SubtiList:BG10819" /db_xref="UniProtKB/Swiss-Prot:P37808" /translation="MSIKAEEISTLIKQQIQNYQSDIEVQDVGTVIQVGDGIARVHGL DNCMAGELVEFSNGVLGMAQNLEESNVGIVILGPFSEIREGDEVKRTGRIMEVPVGEE LIGRIVNPLGQPVDGLGPILTSKTRPIESPAPGVMDRKSVHEPLQTGIKAIDALIPIG RGQRELIIGDRQTGKTSVAIDAILNQKDQDMICVYVAIGQKESTVRGVVETLRKHGAL DYTIVVTASASQPAPLLYLAPYAGVTMAEEFMYNGKHVLVVYDDLSKQAAAYRELSLL LRRPPGREAFPGDVFYLHSRLLERAAKLSDAKGAGSITALPFVETQAGDISAYIPTNV ISITDGQIFLQSDLFFSGVRPAINAGLSVSRVGGSAQIKAMKKVSGTLRLDLASYREL EAFAQFGSDLDQATQAKLNRGARTVEVLKQDLNKPLPVEKQVAILYALTKGYLDDIPV ADIRRFEEEYYMYLDQNHKDLLDGIAKTGNLPADEDFKAAIEGFKRTFAPSN*" gene complement(3649476..3650984) /gene="atpA" /locus_tag="BSU_36830" /old_locus_tag="BSU36830" CDS complement(3651001..3651546) /gene="atpH" /locus_tag="BSU_36840" /old_locus_tag="BSU36840" /EC_number="3.6.3.14" /function="16.10: Respire" /experiment="publication(s) with functional evidences, PMID:8021203, 15347741, 1655755, 22720735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8021203, 15347741, 1655755, 22720735; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="ATP synthase (subunit delta, component F1)" /protein_id="NP_391565.1" /db_xref="EnsemblGenomes-Gn:BSU36840" /db_xref="EnsemblGenomes-Tr:CAB15701" /db_xref="GOA:P37811" /db_xref="InterPro:IPR000711" /db_xref="InterPro:IPR020781" /db_xref="InterPro:IPR026015" /db_xref="SubtiList:BG10818" /db_xref="UniProtKB/Swiss-Prot:P37811" /translation="MSGSAVSKRYASALFDIANESAQLNQVEEELIVVKQVFQNEKAL NDVLNHPKVPAAKKKELIQNAFGSLSQSVLNTIFLLIDRHRAAIVPELTDEFIKLANV ARQTEDAIVYSVKPLTDAEMLPLSQVFAKKAGVASLRIRNEVQTDLIGGIKVRIGNRI YDGSVSGKLQRIERQLAGENR*" gene complement(3651001..3651546) /gene="atpH" /locus_tag="BSU_36840" /old_locus_tag="BSU36840" CDS complement(3651543..3652055) /gene="atpF" /locus_tag="BSU_36850" /old_locus_tag="BSU36850" /EC_number="3.6.3.14" /function="16.10: Respire" /experiment="publication(s) with functional evidences, PMID:1448623, 9069291, 15175330, 22720735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1448623, 9069291, 15175330, 22720735; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="ATP synthase (subunit b, component F0)" /protein_id="NP_391566.1" /db_xref="EnsemblGenomes-Gn:BSU36850" /db_xref="EnsemblGenomes-Tr:CAB15702" /db_xref="GOA:P37814" /db_xref="InterPro:IPR002146" /db_xref="InterPro:IPR005864" /db_xref="InterPro:IPR028987" /db_xref="SubtiList:BG10817" /db_xref="UniProtKB/Swiss-Prot:P37814" /translation="MSQLPLELGLSFNGGDILFQLLAMLILLALLKKYALGPLLNIMK QREDHIAGEITSAEEKNKEAQQLIEEQRVLLKEARQESQTLIENAKKLGEKQKEEIIQ AARAESERLKEAARTEIVKEKEQAVSALREQVASLSVMIASKVIEKELDEQAQEKLIQ DYLKEVGESR*" gene complement(3651543..3652055) /gene="atpF" /locus_tag="BSU_36850" /old_locus_tag="BSU36850" S_feature complement(3652056..3652217) /Source="Nicolas_S_feature" /locus_tag="new_3786458_3786619_c" /HighExp="S2, Lbstat, Mal, M40t90, M0t90, G150, MG-0.1, G135, M0t45, G180" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigL, SigA" /TUshortPSig="0.722, 0.998" /TUlongSig="SigA" /TUlongPSig=1 /label="S1425" CDS complement(3652218..3652430) /gene="atpE" /locus_tag="BSU_36860" /old_locus_tag="BSU36860" /EC_number="3.6.3.14" /function="16.10: Respire" /experiment="publication(s) with functional evidences, PMID:1448623, 9069291, 15175330" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1448623, 9069291, 15175330; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="ATP synthase (subunit c, component F0)" /protein_id="NP_391567.1" /db_xref="EnsemblGenomes-Gn:BSU36860" /db_xref="EnsemblGenomes-Tr:CAB15703" /db_xref="GOA:P37815" /db_xref="InterPro:IPR000454" /db_xref="InterPro:IPR002379" /db_xref="InterPro:IPR005953" /db_xref="InterPro:IPR020537" /db_xref="InterPro:IPR035921" /db_xref="SubtiList:BG10816" /db_xref="UniProtKB/Swiss-Prot:P37815" /translation="MNLIAAAIAIGLGALGAGIGNGLIVSRTVEGIARQPEAGKELRT LMFMGIALVEALPIIAVVIAFLAFFG*" gene complement(3652218..3652430) /gene="atpE" /locus_tag="BSU_36860" /old_locus_tag="BSU36860" CDS complement(3652476..3653210) /gene="atpB" /locus_tag="BSU_36870" /old_locus_tag="BSU36870" /EC_number="3.6.3.14" /function="16.10: Respire" /experiment="publication(s) with functional evidences, PMID:1448623, 9069291, 15175330, 15849754, 16850406" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1448623, 9069291, 15175330, 15849754, 16850406; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="ATP synthase (subunit a, component F0)" /protein_id="NP_391568.1" /db_xref="EnsemblGenomes-Gn:BSU36870" /db_xref="EnsemblGenomes-Tr:CAB15704" /db_xref="GOA:P37813" /db_xref="InterPro:IPR000568" /db_xref="InterPro:IPR023011" /db_xref="InterPro:IPR035908" /db_xref="SubtiList:BG10815" /db_xref="UniProtKB/Swiss-Prot:P37813" /translation="MNHGYRTIEFLGLTFNLTNILMITVASVIVLLIAILTTRTLSIR PGKAQNFMEWIVDFVRNIIGSTMDLKTGANFLALGVTLLMYIFVSNMLGLPFSITIGH ELWWKSPTADPAITLTLAVMVVALTHYYGVKMKGLKEYSKDYLRPVPFMLPMKIIEEF ANTLTLGLRLYGNIFAGEILLGLLAGLATSHYSQSVALGLVGTIGAILPMLAWQAFSL FIGAIQAFIFTMLTMVYMSHKISHDH*" gene complement(3652476..3653210) /gene="atpB" /locus_tag="BSU_36870" /old_locus_tag="BSU36870" promotor_no_box 3653024..3653124 /Source="Nicolas_upshift_promotors" /id="U2896" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.974025974025974" /psig="0.002997002997003" /xcortree=76 /SigmaFactorBS="taatattgcggacgaaatcaacaatccattccataaagttct gggcttttccgggacggatcgaaagcgttcttgtcgtcaatatagcaatcaataaaac a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_no_box" upshifts 3653084 /Source="Nicolas_upshifts" /id="U2896" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.974025974025974" /psig="0.002997002997003" /xcortree=76 /SigmaFactorBS="taatattgcggacgaaatcaacaatccattccataaagttct gggcttttccgggacggatcgaaagcgttcttgtcgtcaatatagcaatcaataaaac a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" CDS complement(3653218..3653601) /gene="atpI" /locus_tag="BSU_36880" /old_locus_tag="BSU36880" /function="16.1: Circulate" /function="16.10: Respire" /experiment="publication(s) with functional evidences, PMID:12917488, 15849754, 16850406, 23123906" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12917488, 15849754, 16850406, 23123906; Product type t: transporter" /codon_start=1 /transl_table=11 /product="ATP synthase (subunit i)" /protein_id="NP_391569.1" /db_xref="EnsemblGenomes-Gn:BSU36880" /db_xref="EnsemblGenomes-Tr:CAB15705" /db_xref="GOA:P37816" /db_xref="InterPro:IPR005598" /db_xref="SubtiList:BG10814" /db_xref="UniProtKB/Swiss-Prot:P37816" /translation="MDDPKLTFSRQRKYLLFILAVYVLGYGLTAYKTVFLGLILGTVF SLFNFLLLVRRMNAFDRAVEKGKSIRSLGSAARWCNAILAVAVAYKNPEYFHMASTVI GLMTIYPVIMIDSFIQLKRSSMEER*" gene complement(3653218..3653601) /gene="atpI" /locus_tag="BSU_36880" /old_locus_tag="BSU36880" misc_feature complement(3653290..3653308) /Source="Nicolas_upshift_promotors" /id="U2897" /multdbtbs="-" /comp="M18" /sig="SigL" /pcomp="0.722277722277722" /psig="0.722277722277722" /xcortree=2708 /SigmaFactorBS="gctgtggctgttgcctataaaaatcccgaatactttcatatg gcAAGTACAGTTATTGGATTAatgacaatataccctgtcattatgatagattccttta t" /listShort="atpB, atpE, S1425, atpF, atpH, atpA, S1424, atpG, atpD, atpC, S1423" /listLong="S1422, ywzB, S1421, ywmB, murAA, S1419, spoIID" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(3653292) /Source="Nicolas_upshifts" /id="U2897" /multdbtbs="-" /comp="M18" /sig="SigL" /pcomp="0.722277722277722" /psig="0.722277722277722" /xcortree=2708 /SigmaFactorBS="gctgtggctgttgcctataaaaatcccgaatactttcatatg gcAAGTACAGTTATTGGATTAatgacaatataccctgtcattatgatagattccttta t" /listShort="atpB, atpE, S1425, atpF, atpH, atpA, S1424, atpG, atpD, atpC, S1423" /listLong="S1422, ywzB, S1421, ywmB, murAA, S1419, spoIID" S_feature complement(3653602..3653872) /Source="Nicolas_S_feature" /locus_tag="new_3788004_3788274_c" /HighExp="M9-stat, T1.30H, T0.30H, T1.0H, UNK1, B60, G135, G180, G150, T2.30H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="0.998, 0.999" /TUlongSig="SigA, SigA" /TUlongPSig="1, 0.96" /label="S1426" promotor_-35 3653834..3653843 /Source="Nicolas_upshift_promotors" /id="U2898" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.955044955044955" /psig="0.955044955044955" /xcortree=1223 /SigmaFactorBS="ttgctgagaggatttacattgaggatgaggactataatgaaa gctatgaaaACCTTCTCATaataccctcgtttAGCATACAATAGCCCCTAACatgtgt c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 3653843 /Source="Nicolas_upshifts" /id="U2898" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.955044955044955" /psig="0.955044955044955" /xcortree=1223 /SigmaFactorBS="ttgctgagaggatttacattgaggatgaggactataatgaaa gctatgaaaACCTTCTCATaataccctcgtttAGCATACAATAGCCCCTAACatgtgt c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 complement(3653848..3653867) /Source="Nicolas_upshift_promotors" /id="U2899" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.577422577422577" /psig="0.998001998001998" /xcortree=2710 /SigmaFactorBS="attctgtggagacgtaaagtataaaaagttttttaactttaa acaGATTGACAcatgttaggggcTATTGTATGCTAAACGAGGGtattatgagaaggtt t" /listShort="S1426, atpI, atpB, atpE, S1425, atpF, atpH, atpA, S1424, atpG, atpD, atpC, S1423" /listLong="S1422, ywzB, S1421, ywmB, murAA, S1419, spoIID" /label="promotor_-10" promotor_-10 3653857..3653876 /Source="Nicolas_upshift_promotors" /id="U2898" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.955044955044955" /psig="0.955044955044955" /xcortree=1223 /SigmaFactorBS="ttgctgagaggatttacattgaggatgaggactataatgaaa gctatgaaaACCTTCTCATaataccctcgtttAGCATACAATAGCCCCTAACatgtgt c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3653872) /Source="Nicolas_upshifts" /id="U2899" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.577422577422577" /psig="0.998001998001998" /xcortree=2710 /SigmaFactorBS="attctgtggagacgtaaagtataaaaagttttttaactttaa acaGATTGACAcatgttaggggcTATTGTATGCTAAACGAGGGtattatgagaaggtt t" /listShort="S1426, atpI, atpB, atpE, S1425, atpF, atpH, atpA, S1424, atpG, atpD, atpC, S1423" /listLong="S1422, ywzB, S1421, ywmB, murAA, S1419, spoIID" S_feature complement(3653874..3653995) /Source="Nicolas_S_feature" /locus_tag="new_3788276_3788397_c" /HighExp="Etha, G180, H2O2, G135, Oxctl, G150, LBGexp, dia15, B36, Paraq" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="1, 0.999" /TUlongSig="SigA" /TUlongPSig="0.96" /label="S1427" promotor_-35 complement(3653880..3653887) /Source="Nicolas_upshift_promotors" /id="U2899" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.577422577422577" /psig="0.998001998001998" /xcortree=2710 /SigmaFactorBS="attctgtggagacgtaaagtataaaaagttttttaactttaa acaGATTGACAcatgttaggggcTATTGTATGCTAAACGAGGGtattatgagaaggtt t" /listShort="S1426, atpI, atpB, atpE, S1425, atpF, atpH, atpA, S1424, atpG, atpD, atpC, S1423" /listLong="S1422, ywzB, S1421, ywmB, murAA, S1419, spoIID" /label="promotor_-35" CDS complement(3654024..3654653) /gene="upp" /locus_tag="BSU_36890" /old_locus_tag="BSU36890" /EC_number="2.4.2.9" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:7798145, 15689504, 15716449" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7798145, 15689504, 15716449; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="uracil phosphoribosyltransferase" /protein_id="NP_391570.1" /db_xref="EnsemblGenomes-Gn:BSU36890" /db_xref="EnsemblGenomes-Tr:CAB15706" /db_xref="GOA:P39149" /db_xref="InterPro:IPR000836" /db_xref="InterPro:IPR005765" /db_xref="InterPro:IPR029057" /db_xref="InterPro:IPR034332" /db_xref="SubtiList:BG10945" /db_xref="UniProtKB/Swiss-Prot:P39149" /translation="MGKVYVFDHPLIQHKLTYIRNENTGTKDFRELVDEVATLMAFEI TRDLPLEEVDINTPVQAAKSKVISGKKLGVVPILRAGLGMVDGILKLIPAAKVGHVGL YRDPETLKPVEYYVKLPSDVEEREFIVVDPMLATGGSAVEAIHSLKKRGAKNIRFMCL VAAPEGVEELQKHHSDVDIYIAALDEKLNEKGYIVPGLGDAGDRMFGTK*" gene complement(3654024..3654653) /gene="upp" /locus_tag="BSU_36890" /old_locus_tag="BSU36890" downshifts complement(3654040) /Source="Nicolas_upshifts" /id="D1907" /incds=0 /nref=180 /ntot=252 /MaxReadThrough="5.83241" /MaxDrop="5.91252" /score="1.39547358" /energy="-7.3" /TU="U2900,U2901" /idTUdmin="U2900" /TUdmin="-154" /isTUend="FALSE" promotor_-10 complement(3654697..3654716) /Source="Nicolas_upshift_promotors" /id="U2900" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.682317682317682" /psig=1 /xcortree=2556 /SigmaFactorBS="aaacccgcttgggcttatgcccggcgggttttttgacgatgt TCTTGAAActcaatgtctttttTTGTAGAATCAATAGAAGTGtgtaattgttgatggg a" /listShort="upp, S1427" /listLong="S1426, atpI, atpB, atpE, S1425, atpF, atpH, atpA, S1424, atpG, atpD, atpC, S1423, S1422, ywzB, S1421, ywmB, murAA, S1419, spoIID" /label="promotor_-10" upshifts complement(3654720) /Source="Nicolas_upshifts" /id="U2900" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.682317682317682" /psig=1 /xcortree=2556 /SigmaFactorBS="aaacccgcttgggcttatgcccggcgggttttttgacgatgt TCTTGAAActcaatgtctttttTTGTAGAATCAATAGAAGTGtgtaattgttgatggg a" /listShort="upp, S1427" /listLong="S1426, atpI, atpB, atpE, S1425, atpF, atpH, atpA, S1424, atpG, atpD, atpC, S1423, S1422, ywzB, S1421, ywmB, murAA, S1419, spoIID" promotor_-35 complement(3654731..3654738) /Source="Nicolas_upshift_promotors" /id="U2900" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.682317682317682" /psig=1 /xcortree=2556 /SigmaFactorBS="aaacccgcttgggcttatgcccggcgggttttttgacgatgt TCTTGAAActcaatgtctttttTTGTAGAATCAATAGAAGTGtgtaattgttgatggg a" /listShort="upp, S1427" /listLong="S1426, atpI, atpB, atpE, S1425, atpF, atpH, atpA, S1424, atpG, atpD, atpC, S1423, S1422, ywzB, S1421, ywmB, murAA, S1419, spoIID" /label="promotor_-35" CDS complement(3654788..3656035) /gene="glyA" /locus_tag="BSU_36900" /old_locus_tag="BSU36900" /EC_number="2.1.2.1" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:11390694, 11902725, 12682299, 12686103, 12923093, 15865438, 18483062" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11390694, 11902725, 12682299, 12686103, 12923093, 15865438, 18483062; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="serine hydroxymethyltransferase" /protein_id="NP_391571.1" /db_xref="EnsemblGenomes-Gn:BSU36900" /db_xref="EnsemblGenomes-Tr:CAB15707" /db_xref="GOA:P39148" /db_xref="InterPro:IPR001085" /db_xref="InterPro:IPR015421" /db_xref="InterPro:IPR015422" /db_xref="InterPro:IPR015424" /db_xref="InterPro:IPR019798" /db_xref="SubtiList:BG10944" /db_xref="UniProtKB/Swiss-Prot:P39148" /translation="MKHLPAQDEQVFNAIKNERERQQTKIELIASENFVSEAVMEAQG SVLTNKYAEGYPGKRYYGGCEHVDVVEDIARDRAKEIFGAEHVNVQPHSGAQANMAVY FTILEQGDTVLGMNLSHGGHLTHGSPVNFSGVQYNFVEYGVDKETQYIDYDDVREKAL AHKPKLIVAGASAYPRTIDFKKFREIADEVGAYFMVDMAHIAGLVAAGLHPNPVPYAD FVTTTTHKTLRGPRGGMILCREEFGKKIDKSIFPGIQGGPLMHVIAAKAVSFGEVLQD DFKTYAQNVISNAKRLAEALTKEGIQLVSGGTDNHLILVDLRSLGLTGKVAEHVLDEI GITSNKNAIPYDPEKPFVTSGIRLGTAAVTSRGFDGDALEEVGAIIALALKNHEDEGK LEEARQRVAALTDKFPLYKELDY*" gene complement(3654788..3656035) /gene="glyA" /locus_tag="BSU_36900" /old_locus_tag="BSU36900" downshifts complement(3654811) /Source="Nicolas_upshifts" /id="D1908" /incds=0 /nref=183 /ntot=229 /MaxReadThrough="5.99283" /MaxDrop="6.62881" /score="22.1245386" /energy="-15.8" /TU="U2901" /idTUdmin="U2902" /TUdmin="-1" /isTUend="TRUE" promotor_-10 complement(3656077..3656096) /Source="Nicolas_upshift_promotors" /id="U2901" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.495504495504495" /psig="0.999000999001" /xcortree=2312 /SigmaFactorBS="tttttaccaataaaaatttagattttttaaaaataatcTTTT ACatcggccttaaaaaCCATGTACAATAGTGATGGTaaaaacaaagaacaggatacgg a" /listShort="glyA, upp, S1427, S1426, atpI" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3656094) /Source="Nicolas_upshifts" /id="U2901" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.495504495504495" /psig="0.999000999001" /xcortree=2312 /SigmaFactorBS="tttttaccaataaaaatttagattttttaaaaataatcTTTT ACatcggccttaaaaaCCATGTACAATAGTGATGGTaaaaacaaagaacaggatacgg a" /listShort="glyA, upp, S1427, S1426, atpI" /GFF_Attribute="listLong" S_feature complement(3656096..3656180) /Source="Nicolas_S_feature" /locus_tag="new_3790498_3790582_c" /HighExp="dia5, C90, dia15, Diami, Lbtran, LPhT, M40t45, H2O2, BI, Sw" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="0.96, 1" /TUlongSig="SigEF" /TUlongPSig="0.999" /label="S1428" promotor_-35 complement(3656111..3656116) /Source="Nicolas_upshift_promotors" /id="U2901" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.495504495504495" /psig="0.999000999001" /xcortree=2312 /SigmaFactorBS="tttttaccaataaaaatttagattttttaaaaataatcTTTT ACatcggccttaaaaaCCATGTACAATAGTGATGGTaaaaacaaagaacaggatacgg a" /listShort="glyA, upp, S1427, S1426, atpI" /GFF_Attribute="listLong" /label="promotor_-35" downshifts complement(3656225) /Source="Nicolas_upshifts" /id="D1909" /incds=0 /nref=3 /ntot=12 /MaxReadThrough="7.23859" /MaxDrop="5.0386" /score="-3.86767322" /energy="-4.3" /TU="U2902,U2903" /idTUdmin="U2904" /TUdmin=1137 /isTUend="FALSE" CDS complement(3656242..3656784) /gene="ywlG" /locus_tag="BSU_36910" /old_locus_tag="BSU36910" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 15995210, 22333191" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_391572.1" /db_xref="EnsemblGenomes-Gn:BSU36910" /db_xref="EnsemblGenomes-Tr:CAB15708" /db_xref="InterPro:IPR006340" /db_xref="InterPro:IPR028345" /db_xref="SubtiList:BG10943" /db_xref="UniProtKB/Swiss-Prot:P39157" /translation="MNELKQTWKTMLSEFQDQAELKQDQLFVLGCSTSEVAGSRIGTS GSVDIAESIYSGLAELREKTGIHLAFQCCEHLNRALVVEAETAKLFRLPTVSAVPVPK AGGAMASYAFKQMKSPVLVETIQADAGIDIGDTFIGMHLKPVAVPVRVSQNSLGSAHV TLARTRPKLIGGVRAVYECE*" gene complement(3656242..3656784) /gene="ywlG" /locus_tag="BSU_36910" /old_locus_tag="BSU36910" CDS complement(3656797..3657246) /gene="rpiB" /locus_tag="BSU_36920" /old_locus_tag="BSU36920" /EC_number="5.3.1.6" /function="16.11: Scavenge (Catabolism)" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:15755726, 15995210, 18640127, 19446032" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15755726, 15995210, 18640127, 19446032; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="D-ribose 5-phosphate epimerase (promiscuous)" /protein_id="NP_391573.1" /db_xref="EnsemblGenomes-Gn:BSU36920" /db_xref="EnsemblGenomes-Tr:CAB15709" /db_xref="GOA:P39156" /db_xref="InterPro:IPR003500" /db_xref="InterPro:IPR004785" /db_xref="InterPro:IPR036569" /db_xref="SubtiList:BG10942" /db_xref="UniProtKB/Swiss-Prot:P39156" /translation="MKVAIASDHGGVHIRNEIKELMDELQIEYIDMGCDCGSGSVDYP DYAFPVAEKVVSGEVDRGILICGTGIGMSISANKVKGIRCALAHDTFSAKATREHNDT NILAMGERVIGPGLAREIAKIWLTTEFTGGRHQTRIGKISDYEEKNL*" gene complement(3656797..3657246) /gene="rpiB" /locus_tag="BSU_36920" /old_locus_tag="BSU36920" S_feature complement(3657247..3657346) /Source="Nicolas_S_feature" /locus_tag="new_3791649_3791748_c" /HighExp="Diami, dia5, C90, dia15, LPhT, M40t45, LBGtran, Lbtran, T-0.40H, H2O2" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.68276199999999998" /TUshortSig="SigA, SigA" /TUshortPSig="0.96, 1" /TUlongSig="SigEF" /TUlongPSig="0.999" /label="S1429" promotor_-10 complement(3657338..3657357) /Source="Nicolas_upshift_promotors" /id="U2902" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.763236763236763" /psig="0.96003996003996" /xcortree=1986 /SigmaFactorBS="ataagttgtcagaaaatctgcaaacaggTCATTTGCaaatcc tgcgtgaAGGAGTAGAATATAGTGAAAagcacatcatatggtgtgaatcaaagagcgg a" /listShort="S1429, ywlF, ywlG, S1428, glyA" /listLong="upp, S1427, S1426, atpI" /label="promotor_-10" upshifts complement(3657346) /Source="Nicolas_upshifts" /id="U2902" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.763236763236763" /psig="0.96003996003996" /xcortree=1986 /SigmaFactorBS="ataagttgtcagaaaatctgcaaacaggTCATTTGCaaatcc tgcgtgaAGGAGTAGAATATAGTGAAAagcacatcatatggtgtgaatcaaagagcgg a" /listShort="S1429, ywlF, ywlG, S1428, glyA" /listLong="upp, S1427, S1426, atpI" promotor_-35 complement(3657371..3657378) /Source="Nicolas_upshift_promotors" /id="U2902" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.763236763236763" /psig="0.96003996003996" /xcortree=1986 /SigmaFactorBS="ataagttgtcagaaaatctgcaaacaggTCATTTGCaaatcc tgcgtgaAGGAGTAGAATATAGTGAAAagcacatcatatggtgtgaatcaaagagcgg a" /listShort="S1429, ywlF, ywlG, S1428, glyA" /listLong="upp, S1427, S1426, atpI" /label="promotor_-35" CDS complement(3657403..3657855) /gene="prpB" /locus_tag="BSU_36930" /old_locus_tag="BSU36930" /EC_number="3.9.1.2" /EC_number="3.1.3.48" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:15995210, 22517742, 24825175, 25610436, 27524296" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15995210, 22517742, 24825175, 25610436, 27524296; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="protein-arginine(tyrosine moonlighting) phosphatase (oxidative stress)" /protein_id="NP_391574.1" /db_xref="EnsemblGenomes-Gn:BSU36930" /db_xref="EnsemblGenomes-Tr:CAB15710" /db_xref="GOA:P39155" /db_xref="InterPro:IPR017867" /db_xref="InterPro:IPR023485" /db_xref="InterPro:IPR036196" /db_xref="PDB:1ZGG" /db_xref="PDB:4ETI" /db_xref="PDB:4ETN" /db_xref="PDB:4KK3" /db_xref="PDB:4KK4" /db_xref="SubtiList:BG10941" /db_xref="UniProtKB/Swiss-Prot:P39155" /translation="MDIIFVCTGNTCRSPMAEALFKSIAEREGLNVNVRSAGVFASPN GKATPHAVEALFEKHIALNHVSSPLTEELMESADLVLAMTHQHKQIIASQFGRYRDKV FTLKEYVTGSHGDVLDPFGGSIDIYKQTRDELEELLRQLAKQLKKDRR*" gene complement(3657403..3657855) /gene="prpB" /locus_tag="BSU_36930" /old_locus_tag="BSU36930" promotor_-10 complement(3657872..3657891) /Source="Nicolas_upshift_promotors" /id="U2903" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.983016983016983" /psig=1 /xcortree=1892 /SigmaFactorBS="agctgcttttgccaatttaatataccaataaaagaaacgaaG TCGccgtttcttttttcTTCATATATAATAGAGAAAAataaggggtgactgacatgga t" /listShort="ywlE, S1429, ywlF, ywlG, S1428, glyA" /listLong="upp" /label="promotor_-10" upshifts complement(3657890) /Source="Nicolas_upshifts" /id="U2903" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.983016983016983" /psig=1 /xcortree=1892 /SigmaFactorBS="agctgcttttgccaatttaatataccaataaaagaaacgaaG TCGccgtttcttttttcTTCATATATAATAGAGAAAAataaggggtgactgacatgga t" /listShort="ywlE, S1429, ywlF, ywlG, S1428, glyA" /listLong="upp" promotor_-35 complement(3657906..3657909) /Source="Nicolas_upshift_promotors" /id="U2903" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.983016983016983" /psig=1 /xcortree=1892 /SigmaFactorBS="agctgcttttgccaatttaatataccaataaaagaaacgaaG TCGccgtttcttttttcTTCATATATAATAGAGAAAAataaggggtgactgacatgga t" /listShort="ywlE, S1429, ywlF, ywlG, S1428, glyA" /listLong="upp" /label="promotor_-35" CDS complement(3657931..3658488) /gene="mntP" /locus_tag="BSU_36940" /old_locus_tag="BSU36940" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 15849754, 16850406, 25774656, 25794618, 26076491; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="manganese efflux pump" /protein_id="NP_391575.1" /db_xref="EnsemblGenomes-Gn:BSU36940" /db_xref="EnsemblGenomes-Tr:CAB15711" /db_xref="GOA:P39154" /db_xref="InterPro:IPR003810" /db_xref="InterPro:IPR022929" /db_xref="SubtiList:BG10940" /db_xref="UniProtKB/Swiss-Prot:P39154" /translation="MSDLFIGELITLSIMAFALGMDAFSVGLGMGMVKLRKKQIFYIG FIIGLFHVIMPLAGMAAGNMLSGLLGVLAVYIGGALLFVLGVQMLMASFKQSEERFMS PAGPGLLLFAIGVSLDSFSVGLSLGIYGSHPLLTITLFGLFSMMLTWLGLLVGKQVQS WLGTYSEALGGIILIVFGLKLLLPI*" gene complement(3657931..3658488) /gene="mntP" /locus_tag="BSU_36940" /old_locus_tag="BSU36940" promotor_-10 complement(3658515..3658533) /Source="Nicolas_upshift_promotors" /id="U2904" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=998 /SigmaFactorBS="cggaggaagagtgattcgctgaaagcagtcagatGTTCTAac cctttttggacacGCATAGGCTAAAAAAGCGGggcgtgtccaagggggttatttatgt a" /listShort="ywlD, ywlE" /listLong="S1429, ywlF, ywlG, S1428, glyA" /label="promotor_-10" upshifts complement(3658528) /Source="Nicolas_upshifts" /id="U2904" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=998 /SigmaFactorBS="cggaggaagagtgattcgctgaaagcagtcagatGTTCTAac cctttttggacacGCATAGGCTAAAAAAGCGGggcgtgtccaagggggttatttatgt a" /listShort="ywlD, ywlE" /listLong="S1429, ywlF, ywlG, S1428, glyA" promotor_-35 complement(3658549..3658554) /Source="Nicolas_upshift_promotors" /id="U2904" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=998 /SigmaFactorBS="cggaggaagagtgattcgctgaaagcagtcagatGTTCTAac cctttttggacacGCATAGGCTAAAAAAGCGGggcgtgtccaagggggttatttatgt a" /listShort="ywlD, ywlE" /listLong="S1429, ywlF, ywlG, S1428, glyA" /label="promotor_-35" CDS complement(3658567..3659607) /gene="tsaC" /locus_tag="BSU_36950" /old_locus_tag="BSU36950" /function="16.2: Construct biomass (Anabolism)" /function="16.13: Shape" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:12682299, 16014871, 16890019, 17005971, 19884342, 20606270, 21775474, 19376873, 19578062, 20701780, 20824107, 21183954, 21285948, 22378793, 23072323, 27913733" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12682299, 16014871, 16890019, 17005971, 19884342, 20606270, 21775474, 19376873, 19578062, 20701780, 20824107, 21183954, 21285948, 22378793, 23072323, 27913733; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="tRNA(NNU) t(6)A37 threonylcarbamoyladenosine modification; threonine-dependent ADP-forming ATPase" /protein_id="NP_391576.1" /db_xref="EnsemblGenomes-Gn:BSU36950" /db_xref="EnsemblGenomes-Tr:CAB15712" /db_xref="GOA:P39153" /db_xref="InterPro:IPR005145" /db_xref="InterPro:IPR006070" /db_xref="InterPro:IPR010923" /db_xref="InterPro:IPR017945" /db_xref="SubtiList:BG10939" /db_xref="UniProtKB/Swiss-Prot:P39153" /translation="MKTKRWFVDVTDELSTNDPQIAQAAALLRENEVVAFPTETVYGL GANAKNTDAVKKIYEAKGRPSDNPLIVHIADISQLEDLTGPAPEKAKTLMKRFWPGAL TLILPCKPDALSPRVTAGLETVAIRMPDHPLALALIRESGLPIAAPSANLSGKPSPTK AEHVAHDLDGRIAGIVDGGPTGIGVESTVLSCADDIPVLLRPGGITKEQIEAVIGPIH VDKGLSDQNEKPISPGMKYTHYAPTAPLAICEGSPERIQHLIQEYQQGGRRVGVLTTE EKAGVYSADYVKSCGRRAQLETVAAGLYDALRSFDENKVDFIIAESFPDTGVGLAIMN RLMKAAGGRVIR*" gene complement(3658567..3659607) /gene="tsaC" /locus_tag="BSU_36950" /old_locus_tag="BSU36950" downshifts complement(3658572) /Source="Nicolas_upshifts" /id="D1910" /incds=0 /nref=4 /ntot=166 /MaxReadThrough="2.08557" /MaxDrop="2.98653" /score="-6.24994287" /energy="-9.8" /TU="NA" /idTUdmin="U2905" /TUdmin=0 /isTUend="TRUE" S_feature complement(3659608..3659672) /Source="Nicolas_S_feature" /locus_tag="new_3794010_3794074_c" /HighExp="dia15, Diami, C90, LBGstat, Heat, LBGtran, dia5, LBGexp, Lbexp, G180" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, Sig-" /TUshortPSig="0.999, 0.444" /TUlongSig="NA" /TUlongPSig="NA" /label="S1430" promotor_-10 complement(3659662..3659681) /Source="Nicolas_upshift_promotors" /id="U2905" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.943056943056943" /psig="0.999000999001" /xcortree=2661 /SigmaFactorBS="ttattagcgttgtccacaatttgtggataacGCTTGttttat tacaggacaTCTTTTATACTTTCAAAAGGattacacgcgtaaaacaatcgttttattg t" /listShort="S1430, ywlC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3659672) /Source="Nicolas_upshifts" /id="U2905" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.943056943056943" /psig="0.999000999001" /xcortree=2661 /SigmaFactorBS="ttattagcgttgtccacaatttgtggataacGCTTGttttat tacaggacaTCTTTTATACTTTCAAAAGGattacacgcgtaaaacaatcgttttattg t" /listShort="S1430, ywlC" /GFF_Attribute="listLong" S_feature complement(3659674..3659763) /Source="Nicolas_S_feature" /locus_tag="new_3794076_3794165_c" /HighExp="S3, M9-stat, Etha, LoTm, T5.0H, S7, S8, S4, BT, S5" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="Sig-" /TUshortPSig="0.444" /TUlongSig="NA" /TUlongPSig="NA" /label="S1431" promotor_-35 complement(3659697..3659701) /Source="Nicolas_upshift_promotors" /id="U2905" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.943056943056943" /psig="0.999000999001" /xcortree=2661 /SigmaFactorBS="ttattagcgttgtccacaatttgtggataacGCTTGttttat tacaggacaTCTTTTATACTTTCAAAAGGattacacgcgtaaaacaatcgttttattg t" /listShort="S1430, ywlC" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3659764..3660207) /gene="ywlB" /locus_tag="BSU_36960" /old_locus_tag="BSU36960" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_391577.1" /db_xref="EnsemblGenomes-Gn:BSU36960" /db_xref="EnsemblGenomes-Tr:CAB15713" /db_xref="InterPro:IPR016181" /db_xref="SubtiList:BG10938" /db_xref="UniProtKB/Swiss-Prot:P39152" /translation="MFYQLRVAREKDGDVLEAFLKQAKTSYEGVKEGFTQFLMLEDSE KNIAGCLGIEKISCDQGLLRSLVISDKLHQGHIVTLFQSMEVLCEKHQIKTVYLVANQ HSSADFLTAMGFERAESVPEELFSSDHFCESRQTEGAVLMKKASG*" gene complement(3659764..3660207) /gene="ywlB" /locus_tag="BSU_36960" /old_locus_tag="BSU36960" CDS complement(3660274..3660948) /gene="spoIIR" /locus_tag="BSU_36970" /old_locus_tag="BSU36970" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:15044948, 16824103, 18378688, 20802044, 22111992" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15044948, 16824103, 18378688, 20802044, 22111992; Product type r: regulator" /codon_start=1 /transl_table=11 /product="regulator signal of pro-sigma(E) spoIIGA endopeptidase (stage II sporulation)" /protein_id="NP_391578.1" /db_xref="EnsemblGenomes-Gn:BSU36970" /db_xref="EnsemblGenomes-Tr:CAB15714" /db_xref="GOA:P39151" /db_xref="InterPro:IPR014202" /db_xref="SubtiList:BG10937" /db_xref="UniProtKB/Swiss-Prot:P39151" /translation="MKKTVIICIYIFLLLSGALVGLAKEETAQKSENQPVVIPDQAIR LRILANSDSDQDQQLKRHIRDAVNKEITTWVKDITSIEEARRVIRSKLPEIKAIAKET MEKEGANQSISVDFDKISFPTKLYGNMVYPAGEYEAILITLGNGDGANWWCVLFPPLC FLDFSNGEAVKEQEDKEASKKQTEKVLEDVTAKAEKAKKEENEEKEDGTEVKFFLVEW ISDLFS*" gene complement(3660274..3660948) /gene="spoIIR" /locus_tag="BSU_36970" /old_locus_tag="BSU36970" promotor_-10 complement(3660710..3660728) /Source="Nicolas_upshift_promotors" /id="U2906" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.992007992007992" /psig="0.992007992007992" /xcortree=243 /SigmaFactorBS="caattaaaacgtcatataagagacgcggTGAATAAagaaatc acaacttGGGTAAAGGATATTACTTCtattgaagaagcgcgtcgcgtgattcgttcaa a" /listShort="ywlB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3660717) /Source="Nicolas_upshifts" /id="U2906" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.992007992007992" /psig="0.992007992007992" /xcortree=243 /SigmaFactorBS="caattaaaacgtcatataagagacgcggTGAATAAagaaatc acaacttGGGTAAAGGATATTACTTCtattgaagaagcgcgtcgcgtgattcgttcaa a" /listShort="ywlB" /GFF_Attribute="listLong" promotor_-35 complement(3660743..3660749) /Source="Nicolas_upshift_promotors" /id="U2906" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.992007992007992" /psig="0.992007992007992" /xcortree=243 /SigmaFactorBS="caattaaaacgtcatataagagacgcggTGAATAAagaaatc acaacttGGGTAAAGGATATTACTTCtattgaagaagcgcgtcgcgtgattcgttcaa a" /listShort="ywlB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(3660980..3660997) /Source="Nicolas_upshift_promotors" /id="U2907" /multdbtbs="SigF" /comp="M3" /sig="Sig-" /pcomp="0.443556443556444" /psig="0.443556443556444" /xcortree=964 /SigmaFactorBS="tgctagatttttttcaccctgcaCGTTTAtcccaggctctcc ttGTCCATAATAGGGCTAGAaacaaagcacggagaggaacggtggggaccgatgaaaa a" /listShort="spoIIR, ywlB, S1431, S1430, ywlC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3660981) /Source="Nicolas_upshifts" /id="U2907" /multdbtbs="SigF" /comp="M3" /sig="Sig-" /pcomp="0.443556443556444" /psig="0.443556443556444" /xcortree=964 /SigmaFactorBS="tgctagatttttttcaccctgcaCGTTTAtcccaggctctcc ttGTCCATAATAGGGCTAGAaacaaagcacggagaggaacggtggggaccgatgaaaa a" /listShort="spoIIR, ywlB, S1431, S1430, ywlC" /GFF_Attribute="listLong" promotor_-35 complement(3661013..3661018) /Source="Nicolas_upshift_promotors" /id="U2907" /multdbtbs="SigF" /comp="M3" /sig="Sig-" /pcomp="0.443556443556444" /psig="0.443556443556444" /xcortree=964 /SigmaFactorBS="tgctagatttttttcaccctgcaCGTTTAtcccaggctctcc ttGTCCATAATAGGGCTAGAaacaaagcacggagaggaacggtggggaccgatgaaaa a" /listShort="spoIIR, ywlB, S1431, S1430, ywlC" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 3661054 /Source="Nicolas_upshifts" /id="U2908" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.967032967032967" /psig=1 /xcortree=2167 /SigmaFactorBS="ggacaaggagagcctgggataaacgtgcagggtgaaaaaaat ctagcaagctgttaatcttattTATGGTACGATAGTGTTTTAggaggtttaagatgaa a" /listShort="ywlA" /GFF_Attribute="listLong" misc_feature 3661058..3661077 /Source="Nicolas_upshift_promotors" /id="U2908" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.967032967032967" /psig=1 /xcortree=2167 /SigmaFactorBS="ggacaaggagagcctgggataaacgtgcagggtgaaaaaaat ctagcaagctgttaatcttattTATGGTACGATAGTGTTTTAggaggtttaagatgaa a" /listShort="ywlA" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" CDS 3661089..3661451 /gene="ywlA" /locus_tag="BSU_36980" /old_locus_tag="BSU36980" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406, 22720735; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative integral inner membrane protein" /protein_id="NP_391579.1" /db_xref="EnsemblGenomes-Gn:BSU36980" /db_xref="EnsemblGenomes-Tr:CAB15715" /db_xref="GOA:P39150" /db_xref="InterPro:IPR031374" /db_xref="SubtiList:BG10936" /db_xref="UniProtKB/Swiss-Prot:P39150" /translation="MKYNYTVLLSAFTMSVLYSVIYIHSFIIAALITMAFYFLFPYLI FALPLQIMMNKKPKRFSPLYLLYYLAAAFIANAIIFGMLQPSGQSLFQNTAFYLFAVL TALIYWIWDSVLLQKKEA*" gene 3661089..3661451 /gene="ywlA" /locus_tag="BSU_36980" /old_locus_tag="BSU36980" downshifts complement(3661464) /Source="Nicolas_upshifts" /id="D1911" /incds=0 /nref=27 /ntot=242 /MaxReadThrough="2.64328" /MaxDrop="5.72616" /score="26.8558862" /energy="-11.3" /TU="U2910" /idTUdmin="U2909" /TUdmin=12 /isTUend="TRUE" CDS complement(3661468..3661755) /gene="ywkF" /locus_tag="BSU_36990" /old_locus_tag="BSU36990" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_391580.1" /db_xref="EnsemblGenomes-Gn:BSU36990" /db_xref="EnsemblGenomes-Tr:CAB15716" /db_xref="GOA:P45874" /db_xref="InterPro:IPR035167" /db_xref="SubtiList:BG11317" /db_xref="UniProtKB/Swiss-Prot:P45874" /translation="MKKALTAGILLIAIESMIGTIFPQALSYEAIFGVASLVLVGLAI ITSGLAVSGSDQRANYHSETKEGRTSRMKMAAAFFVAAIPSILCYLLTILF*" gene complement(3661468..3661755) /gene="ywkF" /locus_tag="BSU_36990" /old_locus_tag="BSU36990" S_feature complement(3661756..3661814) /Source="Nicolas_S_feature" /locus_tag="new_3796158_3796216_c" /HighExp="S6, S8, S7, BT, G135, G180, Paraq, H2O2, G150, Oxctl" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigK, SigA" /TUshortPSig="1, 0.998" /TUlongSig="NA" /TUlongPSig="NA" /label="S1432" promotor_-10 complement(3661812..3661831) /Source="Nicolas_upshift_promotors" /id="U2909" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1326 /SigmaFactorBS="cggaagtggaagtgctgaaagatattaatggaaaaGACAGAA CCAtatgcgctctgaTTCATAAAAATAAATAAGCAgcttgctggcgagtgaatggatc a" /listShort="S1432, ywkF" /GFF_Attribute="listLong" /label="promotor_-10" CDS complement(3661815..3662681) /gene="prmC" /locus_tag="BSU_37000" /old_locus_tag="BSU37000" /EC_number="2.1.1.297" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 16014871, 16364916, 22720735; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="glutamine methylase of release factor 1 (and perhaps others) at a GGQ site" /protein_id="NP_391581.1" /db_xref="EnsemblGenomes-Gn:BSU37000" /db_xref="EnsemblGenomes-Tr:CAB15717" /db_xref="GOA:P45873" /db_xref="InterPro:IPR002052" /db_xref="InterPro:IPR004556" /db_xref="InterPro:IPR007848" /db_xref="InterPro:IPR019874" /db_xref="InterPro:IPR029063" /db_xref="SubtiList:BG11316" /db_xref="UniProtKB/Swiss-Prot:P45873" /translation="MKTIFEALKWASSYLTEAGREENAAELLLLYDTGMERSKLLASL QEPIGEDELYRFKRHVEMHKEGVPVQYIIGKEFFYGREFMVNDDVLIPRPETEEVVFH LLEKYRSVFSEDGKLEVVDVGTGSGAIAVTLALENQSFSVSAVDISKEALQVASANAE KLGANVRFYQGDLLEPFIKAGKKADIIVSNPPYISEEEMADLSEIVRFHEPLHALTDG GDGLKFYKRFMEDIPLVMKDKVFVVFEIGWKQGAAVKDLILKAFKGAEVEVLKDINGK DRTICALIHKNK*" gene complement(3661815..3662681) /gene="prmC" /locus_tag="BSU_37000" /old_locus_tag="BSU37000" upshifts complement(3661828) /Source="Nicolas_upshifts" /id="U2909" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1326 /SigmaFactorBS="cggaagtggaagtgctgaaagatattaatggaaaaGACAGAA CCAtatgcgctctgaTTCATAAAAATAAATAAGCAgcttgctggcgagtgaatggatc a" /listShort="S1432, ywkF" /GFF_Attribute="listLong" promotor_-35 complement(3661844..3661853) /Source="Nicolas_upshift_promotors" /id="U2909" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1326 /SigmaFactorBS="cggaagtggaagtgctgaaagatattaatggaaaaGACAGAA CCAtatgcgctctgaTTCATAAAAATAAATAAGCAgcttgctggcgagtgaatggatc a" /listShort="S1432, ywkF" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3662683..3663753) /gene="prfA" /locus_tag="BSU_37010" /old_locus_tag="BSU37010" /experiment="publication(s) with functional evidences, PMID:2186375, 1408743, 10446248, 12237459, 12682299" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 2186375, 1408743, 10446248, 12237459, 12682299; Product type f: factor" /codon_start=1 /transl_table=11 /product="peptide chain release factor 1" /protein_id="NP_391582.1" /db_xref="EnsemblGenomes-Gn:BSU37010" /db_xref="EnsemblGenomes-Tr:CAB15718" /db_xref="GOA:P45872" /db_xref="InterPro:IPR000352" /db_xref="InterPro:IPR004373" /db_xref="InterPro:IPR005139" /db_xref="SubtiList:BG11244" /db_xref="UniProtKB/Swiss-Prot:P45872" /translation="MLDRLKSIEERYEKLNELLSDPEVVNDPKKLREYSKEQSDIQET VDVYRQYRDASEQLADAKAMLEEKLDAEMRDMVKEEISELQKETETLSERLKVLLIPK DPNDDKNVIMEIRGAAGGEEAALFAGNLYRMYSRYAELQGWKTEVMEANVTGTGGYKE IIFMITGSGAYSKLKYENGAHRVQRVPETESGGRIHTSTATVACLPEAEEVEVDIHEK DIRVDTFASSGPGGQSVNTTMSAVRLTHLPTGVVVSCQDEKSQIKNKEKAMKVLRARI YDKFQQEAQAEYDQTRKSAVGSGDRSERIRTYNFPQNRVTDHRIGLTIQKLDQILEGK LDEVVEALIVEDQASKLQQSEG*" gene complement(3662683..3663753) /gene="prfA" /locus_tag="BSU_37010" /old_locus_tag="BSU37010" downshifts complement(3662686) /Source="Nicolas_upshifts" /id="D1912" /incds=0 /nref=23 /ntot=212 /MaxReadThrough="5.17118" /MaxDrop="3.44681" /score="-9.55295942" /energy="-10.5" /TU="U2910" /idTUdmin="U2912" /TUdmin=1122 /isTUend="FALSE" downshifts 3663754 /Source="Nicolas_upshifts" /id="D1913" /incds=0 /nref=1 /ntot=68 /MaxReadThrough="1.13519" /MaxDrop="4.28706" /score="36.3991981" /energy="-10.4" /TU="NA" /idTUdmin="U2911" /TUdmin="-990" /isTUend="FALSE" promotor_-10 complement(3663781..3663800) /Source="Nicolas_upshift_promotors" /id="U2910" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.45954045954046" /psig="0.998001998001998" /xcortree=2501 /SigmaFactorBS="attccagtatagcagagggagcttttccagctgggattgaaa tgcTTTTGACtggggttaatcacTATACTATAATGAGAATGTTacgcacaggaaaaca g" /listShort="prfA, prmC, S1432, ywkF" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3663805) /Source="Nicolas_upshifts" /id="U2910" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.45954045954046" /psig="0.998001998001998" /xcortree=2501 /SigmaFactorBS="attccagtatagcagagggagcttttccagctgggattgaaa tgcTTTTGACtggggttaatcacTATACTATAATGAGAATGTTacgcacaggaaaaca g" /listShort="prfA, prmC, S1432, ywkF" /GFF_Attribute="listLong" S_feature complement(3663807..3663918) /Source="Nicolas_S_feature" /locus_tag="new_3798209_3798320_c" /HighExp="S6, S8, S7, BT, S5, Etha, B36, C30, S4, GM 25" /AntisenseName="ywkD" /AntisenseCor="-0.43140174721346802" /AntisenseRegPval="-12.9" /CDS_PredictionProba="NA" /TUshortSig="SigK" /TUshortPSig="0.927" /TUlongSig="NA" /TUlongPSig="NA" /label="S1433" promotor_-35 complement(3663814..3663820) /Source="Nicolas_upshift_promotors" /id="U2910" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.45954045954046" /psig="0.998001998001998" /xcortree=2501 /SigmaFactorBS="attccagtatagcagagggagcttttccagctgggattgaaa tgcTTTTGACtggggttaatcacTATACTATAATGAGAATGTTacgcacaggaaaaca g" /listShort="prfA, prmC, S1432, ywkF" /GFF_Attribute="listLong" /label="promotor_-35" misc_feature 3663850..3663869 /Source="Nicolas_upshift_promotors" /id="U2911" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.561438561438561" /psig="0.99100899100899" /xcortree=2343 /SigmaFactorBS="attaaccccagtcaaaagcatttcaatcccagctggaaaagc tcccTCTGCTATACTGGAATTCGAggagggatgatgttgctgaaatccatacatcata t" /listShort="ywkD, racA" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 3663864 /Source="Nicolas_upshifts" /id="U2911" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.561438561438561" /psig="0.99100899100899" /xcortree=2343 /SigmaFactorBS="attaaccccagtcaaaagcatttcaatcccagctggaaaagc tcccTCTGCTATACTGGAATTCGAggagggatgatgttgctgaaatccatacatcata t" /listShort="ywkD, racA" /GFF_Attribute="listLong" CDS 3663879..3664265 /gene="ywkD" /locus_tag="BSU_37020" /old_locus_tag="BSU37020" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative enzyme" /protein_id="NP_391583.1" /db_xref="EnsemblGenomes-Gn:BSU37020" /db_xref="EnsemblGenomes-Tr:CAB15719" /db_xref="GOA:P45871" /db_xref="InterPro:IPR004360" /db_xref="InterPro:IPR029068" /db_xref="SubtiList:BG11315" /db_xref="UniProtKB/Swiss-Prot:P45871" /translation="MLLKSIHHIAIICSDYEKSKAFYVHKLGFQVIQETYREERGSYK LDLSLNGSYVIELFSFPDPPERQTRPEAAGLRHLAFTVGSLDKAVQELHEKGIETEPI RTDPLTGKRFTFFFDPDQLPLELYEQ*" gene 3663879..3664265 /gene="ywkD" /locus_tag="BSU_37020" /old_locus_tag="BSU37020" promotor_-10 complement(3663900..3663918) /Source="Nicolas_upshift_promotors" /id="U2912" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.927072927072927" /psig="0.927072927072927" /xcortree=1264 /SigmaFactorBS="cttgaatcacctgaaaaccaagcttatgtacgtagaaagCTT TCGACttttcgtaatctgAACATATGATTGCAATATGatgtatggatttcagcaacat c" /listShort="S1433" /listLong="prfA" /label="promotor_-10" upshifts complement(3663918) /Source="Nicolas_upshifts" /id="U2912" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.927072927072927" /psig="0.927072927072927" /xcortree=1264 /SigmaFactorBS="cttgaatcacctgaaaaccaagcttatgtacgtagaaagCTT TCGACttttcgtaatctgAACATATGATTGCAATATGatgtatggatttcagcaacat c" /listShort="S1433" /listLong="prfA" promotor_-35 complement(3663932..3663939) /Source="Nicolas_upshift_promotors" /id="U2912" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.927072927072927" /psig="0.927072927072927" /xcortree=1264 /SigmaFactorBS="cttgaatcacctgaaaaccaagcttatgtacgtagaaagCTT TCGACttttcgtaatctgAACATATGATTGCAATATGatgtatggatttcagcaacat c" /listShort="S1433" /listLong="prfA" /label="promotor_-35" promotor_-35 3664333..3664341 /Source="Nicolas_upshift_promotors" /id="U2913" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp=1 /psig=1 /xcortree=449 /SigmaFactorBS="ccactttctttgccgaatcttttcttgttttgtctaacggGA AGGGAACcgcattctatGGTCGAATACCTAGCTTAAaaggaggtatgggatcatgaat a" /listShort="racA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3664352..3664370 /Source="Nicolas_upshift_promotors" /id="U2913" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp=1 /psig=1 /xcortree=449 /SigmaFactorBS="ccactttctttgccgaatcttttcttgttttgtctaacggGA AGGGAACcgcattctatGGTCGAATACCTAGCTTAAaaggaggtatgggatcatgaat a" /listShort="racA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3664353 /Source="Nicolas_upshifts" /id="U2913" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp=1 /psig=1 /xcortree=449 /SigmaFactorBS="ccactttctttgccgaatcttttcttgttttgtctaacggGA AGGGAACcgcattctatGGTCGAATACCTAGCTTAAaaggaggtatgggatcatgaat a" /listShort="racA" /GFF_Attribute="listLong" CDS 3664387..3664941 /gene="racA" /locus_tag="BSU_37030" /old_locus_tag="BSU37030" /function="16.2: Construct biomass (Anabolism)" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:15780934, 17139259, 19478798, 22720735, 27059541, 27085804" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15780934, 17139259, 19478798, 22720735, 27059541, 27085804; Product type f : factor" /codon_start=1 /transl_table=11 /product="chromosome-pole-anchoring protein RacA" /protein_id="NP_391584.1" /db_xref="EnsemblGenomes-Gn:BSU37030" /db_xref="EnsemblGenomes-Tr:CAB15720" /db_xref="GOA:P45870" /db_xref="InterPro:IPR000551" /db_xref="InterPro:IPR009061" /db_xref="InterPro:IPR023522" /db_xref="PDB:5I41" /db_xref="PDB:5I44" /db_xref="SubtiList:BG11314" /db_xref="UniProtKB/Swiss-Prot:P45870" /translation="MNTNMVASELGVSAKTVQRWVKQLNLPAERNELGHYSFTAEDVK VLKSVQKQISEGTAIQDIHLPKSAKKRTGFLVQKTSSDTERRIEQLEQKLDTLLQQRQ DESELMARMSELERQLKQKADEGVSYQLLQHRREIDDILADLQSLTSQMKEFTAHSIP ETAAASEKTKTRKKPLLSLFKFQT*" gene 3664387..3664941 /gene="racA" /locus_tag="BSU_37030" /old_locus_tag="BSU37030" misc_feature 3664871..3664875 /Source="Nicolas_upshift_promotors" /id="U2914" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.747252747252747" /psig="0.015984015984016" /xcortree=450 /SigmaFactorBS="ctgcaatcactgacctcacaaatgaaagaattcaccgctcat tcgatccccgagaCTGCTgctgcttctgaaaaaaccaaaacaagaaaaaaaccgctgc t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 3664876 /Source="Nicolas_upshifts" /id="U2914" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.747252747252747" /psig="0.015984015984016" /xcortree=450 /SigmaFactorBS="ctgcaatcactgacctcacaaatgaaagaattcaccgctcat tcgatccccgagaCTGCTgctgcttctgaaaaaaccaaaacaagaaaaaaaccgctgc t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" downshifts 3664920 /Source="Nicolas_upshifts" /id="D1914" /incds=0 /nref=213 /ntot=274 /MaxReadThrough="0.82868" /MaxDrop="8.28021" /score="36.3991981" /energy="-10.4" /TU="U2913" /idTUdmin="U2914" /TUdmin=0 /isTUend="TRUE" CDS complement(3664975..3665934) /gene="ywkB" /locus_tag="BSU_37040" /old_locus_tag="BSU37040" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 12949160, 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative metabolite transporter" /protein_id="NP_391585.1" /db_xref="EnsemblGenomes-Gn:BSU37040" /db_xref="EnsemblGenomes-Tr:CAB15721" /db_xref="GOA:P45869" /db_xref="InterPro:IPR004776" /db_xref="InterPro:IPR014024" /db_xref="SubtiList:BG11313" /db_xref="UniProtKB/Swiss-Prot:P45869" /translation="MSILDILILLAPIFFVIVLGWFAGHFGSYDAKSAKGVSTLVTKY ALPAHFIAGILTTSRSEFLSQVPLMISLIIGIVGFYIIILLVCRFIFKYDLTNSSVFS LNSAQPTFAFMGIPVLGSLFGANEVAIPIAVTGIVVNAILDPLAIIIATVGESSKKNE ESGDSFWKMTGKSILHGLCEPLAAAPLISMILVLVFNFTLPELGVKMLDQLGSTTSGV ALFAVGVTVGIRKIKLSMPAIGIALLKVAVQPALMFLIALAIGLPADQTTKAILLVAF PGSAVAAMIATRFEKQEEETATAFVVSAILSLISLPIIIALTA*" gene complement(3664975..3665934) /gene="ywkB" /locus_tag="BSU_37040" /old_locus_tag="BSU37040" downshifts complement(3664997) /Source="Nicolas_upshifts" /id="D1915" /incds=0 /nref=36 /ntot=74 /MaxReadThrough="2.86006" /MaxDrop="4.78642" /score="20.048754" /energy="-10.4" /TU="U2916" /idTUdmin="U2917" /TUdmin="-1" /isTUend="TRUE" promotor_-10 complement(3665972..3665990) /Source="Nicolas_upshift_promotors" /id="U2915" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.994005994005994" /psig="0.994005994005994" /xcortree=735 /SigmaFactorBS="acctgaatacaaaaaagtcatcgcgaaataattagCGAGTAA atttttctgtccgaGGGAAAGCTTTTTGTAAAGctaaagtatacggacataggatttg g" /listShort="ywkB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3665986) /Source="Nicolas_upshifts" /id="U2915" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.994005994005994" /psig="0.994005994005994" /xcortree=735 /SigmaFactorBS="acctgaatacaaaaaagtcatcgcgaaataattagCGAGTAA atttttctgtccgaGGGAAAGCTTTTTGTAAAGctaaagtatacggacataggatttg g" /listShort="ywkB" /GFF_Attribute="listLong" promotor_-35 complement(3666005..3666011) /Source="Nicolas_upshift_promotors" /id="U2915" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.994005994005994" /psig="0.994005994005994" /xcortree=735 /SigmaFactorBS="acctgaatacaaaaaagtcatcgcgaaataattagCGAGTAA atttttctgtccgaGGGAAAGCTTTTTGTAAAGctaaagtatacggacataggatttg g" /listShort="ywkB" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3666016..3667764) /gene="maeA" /locus_tag="BSU_37050" /old_locus_tag="BSU37050" /EC_number="1.1.1.38" /function="16.11: Scavenge (Catabolism)" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:12949160, 16788182, 20933603, 22740702, 23136871, 24325460" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12949160, 16788182, 20933603, 22740702, 23136871, 24325460; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="NAD-dependent malic enzyme (conversion of malateinto pyruvate)" /protein_id="NP_391586.1" /db_xref="EnsemblGenomes-Gn:BSU37050" /db_xref="EnsemblGenomes-Tr:CAB15722" /db_xref="GOA:P45868" /db_xref="InterPro:IPR001891" /db_xref="InterPro:IPR012301" /db_xref="InterPro:IPR012302" /db_xref="InterPro:IPR015884" /db_xref="InterPro:IPR036291" /db_xref="InterPro:IPR037062" /db_xref="SubtiList:BG11312" /db_xref="UniProtKB/Swiss-Prot:P45868" /translation="MGYYLTWLTISRKKEICLNNIKKTKEGHLETTLRGKEVLSIPTL NKGVAFSLEERQELGLEGLLPPTVLSLDQQAQRAYEQFQAQPDRLRQNVYLSDLANRN EVLFYKLLKNHLREMLPVVYTPTVGEAIQEYSHEYRRPQGIYLSIDNIDGIEKAFENL HATAGDIDLIVATDSESILGIGDWGVGGINIAIGKLAVYTAAAGIDPSRVIPVVLDVG TNNEKLLNDPLYIGNKHERVQGERYEAFIDAYVKAALKFFPKALLHWEDLGNKNARNI MKKYNHEILTFNDDIQGTGAITLAGVLAAMKKTGASIKDQRVVIFGAGSAGIGIADQI RDTMVLAGLSEEEANKRFYTLDYRGLLTEDIEGILDFQKPYLRNADEVKDWKRDEKGQ IPFDEVVRQAKPTILIGTSGVSGAFTEEIVKEMASHVDRPVIMPMSNPTHLAEAVPED LFKWTDGKVLIATGSPFDNVEYNGVSYEIGQSNNAFAFPGLGLGSIVAEARIITPAMF AATADAIAEMVDLETPGAGLLPSIDKLQEVSIQVAIAVAEAAIKDGVANRQPEDVKQA VLDAMWTPEYKKVIAK*" gene complement(3666016..3667764) /gene="maeA" /locus_tag="BSU_37050" /old_locus_tag="BSU37050" promotor_-10 complement(3666490..3666508) /Source="Nicolas_upshift_promotors" /id="U2916" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=177 /SigmaFactorBS="aaaccaacaatcttgattggtacttcaggGGTTTCAggtgca ttcacagaGGAAATTGTAAAAGAAATGgcatctcacgtagaccgtccggttatcatgc c" /listShort="ywkB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3666498) /Source="Nicolas_upshifts" /id="U2916" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=177 /SigmaFactorBS="aaaccaacaatcttgattggtacttcaggGGTTTCAggtgca ttcacagaGGAAATTGTAAAAGAAATGgcatctcacgtagaccgtccggttatcatgc c" /listShort="ywkB" /GFF_Attribute="listLong" promotor_-35 complement(3666523..3666529) /Source="Nicolas_upshift_promotors" /id="U2916" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=177 /SigmaFactorBS="aaaccaacaatcttgattggtacttcaggGGTTTCAggtgca ttcacagaGGAAATTGTAAAAGAAATGgcatctcacgtagaccgtccggttatcatgc c" /listShort="ywkB" /GFF_Attribute="listLong" /label="promotor_-35" S_feature complement(3667765..3667855) /Source="Nicolas_S_feature" /locus_tag="new_3802167_3802257_c" /HighExp="GM 25, GM 15, GM 60, GM 90, GM 120, MG-0.2, MG 15, GM 45, MG-0.1, GM 10" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S1434" promotor_-10 complement(3667839..3667858) /Source="Nicolas_upshift_promotors" /id="U2917" /multdbtbs="SigA" /comp="M17" /sig="SigA" /pcomp="0.731268731268731" /psig="0.999000999001" /xcortree=1757 /SigmaFactorBS="aaataagtatattaaaaaattaagtaattttcttctCTTGAA TTttgattttgacagGCATACAATAGCTTACGTAAtgtaaatagttttgagacattgt t" /listShort="S1434, maeA, ywkB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3667855) /Source="Nicolas_upshifts" /id="U2917" /multdbtbs="SigA" /comp="M17" /sig="SigA" /pcomp="0.731268731268731" /psig="0.999000999001" /xcortree=1757 /SigmaFactorBS="aaataagtatattaaaaaattaagtaattttcttctCTTGAA TTttgattttgacagGCATACAATAGCTTACGTAAtgtaaatagttttgagacattgt t" /listShort="S1434, maeA, ywkB" /GFF_Attribute="listLong" promotor_-35 complement(3667872..3667879) /Source="Nicolas_upshift_promotors" /id="U2917" /multdbtbs="SigA" /comp="M17" /sig="SigA" /pcomp="0.731268731268731" /psig="0.999000999001" /xcortree=1757 /SigmaFactorBS="aaataagtatattaaaaaattaagtaattttcttctCTTGAA TTttgattttgacagGCATACAATAGCTTACGTAAtgtaaatagttttgagacattgt t" /listShort="S1434, maeA, ywkB" /GFF_Attribute="listLong" /label="promotor_-35" downshifts complement(3667998) /Source="Nicolas_upshifts" /id="D1916" /incds=0 /nref=11 /ntot=126 /MaxReadThrough="2.81368" /MaxDrop="3.39095" /score="20.3711149" /energy="-7.5" /TU="NA" /idTUdmin="U2918" /TUdmin="-10" /isTUend="TRUE" CDS complement(3668003..3668590) /gene="tdk" /locus_tag="BSU_37060" /old_locus_tag="BSU37060" /EC_number="2.7.1.21" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 2423635, 17132103; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="thymidine kinase" /protein_id="NP_391587.1" /db_xref="EnsemblGenomes-Gn:BSU37060" /db_xref="EnsemblGenomes-Tr:CAB15723" /db_xref="GOA:Q03221" /db_xref="InterPro:IPR001267" /db_xref="InterPro:IPR020633" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG10419" /db_xref="UniProtKB/Swiss-Prot:Q03221" /translation="MYIMKQSGWLELICGSMFSGKSEELIRRVKRATYAKQEVRVFKP VIDNRYSEAAVVSHNGTSMTSYAISSAADIWDHISESTDVVAVDEVQFFDQEIVEVLS SLADKGYRVIAAGLDMDFRGEPFGVVPNIMAIAESVTKLQAVCSVCGSPASRTQRLID GKPASYDDPVILVGAAESYEARCRHHHEVPGKSKK*" gene complement(3668003..3668590) /gene="tdk" /locus_tag="BSU_37060" /old_locus_tag="BSU37060" CDS complement(3668679..3668879) /gene="rpmEA" /locus_tag="BSU_37070" /old_locus_tag="BSU37070" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:12682299, 15049826, 16014871, 16547061, 17163968, 17310068, 19648245, 20208344, 27561249" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12682299, 15049826, 16014871, 16547061, 17163968, 17310068, 19648245, 20208344, 27561249; Product type s: structure" /codon_start=1 /transl_table=11 /product="ribosomal protein L31" /protein_id="NP_391588.1" /db_xref="EnsemblGenomes-Gn:BSU37070" /db_xref="EnsemblGenomes-Tr:CAB15724" /db_xref="GOA:Q03223" /db_xref="InterPro:IPR002150" /db_xref="InterPro:IPR027491" /db_xref="InterPro:IPR034704" /db_xref="PDB:3J9W" /db_xref="PDB:5NJT" /db_xref="SubtiList:BG10417" /db_xref="UniProtKB/Swiss-Prot:Q03223" /translation="MKAGIHPNFKKATVKCACGNEFETGSVKEEVRVEICSECHPFYT GRQKFASADGRVDRFNKKYGLK*" gene complement(3668679..3668879) /gene="rpmEA" /locus_tag="BSU_37070" /old_locus_tag="BSU37070" downshifts complement(3668692) /Source="Nicolas_upshifts" /id="D1917" /incds=0 /nref=268 /ntot=279 /MaxReadThrough="5.35148" /MaxDrop="6.82076" /score="15.63162" /energy="-10.3" /TU="U2918,U2919" /idTUdmin="U2921" /TUdmin=0 /isTUend="TRUE" S_feature complement(3668880..3668957) /Source="Nicolas_S_feature" /locus_tag="new_3803282_3803359_c" /HighExp="HPh, LPh, LPhT, GM 45, Paraq, MG 45, MG 60, aero, LBGexp, MG 10" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA, SigA" /TUshortPSig="0.999, 0.811, 1" /TUlongSig="SigH, SigA" /TUlongPSig="1, 0.997" /label="S1435" promotor_-10 complement(3668953..3668972) /Source="Nicolas_upshift_promotors" /id="U2918" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.49050949050949" /psig="0.999000999001" /xcortree=2639 /SigmaFactorBS="tatcatctgcaagaaggtaaattgTATTTGCAaaagaagtaa atcACTGATATAATTTTCTCATAtgcgtttcggacaatgctccgaaataataactctg t" /listShort="S1435, rpmEA, tdk" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3668957) /Source="Nicolas_upshifts" /id="U2918" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.49050949050949" /psig="0.999000999001" /xcortree=2639 /SigmaFactorBS="tatcatctgcaagaaggtaaattgTATTTGCAaaagaagtaa atcACTGATATAATTTTCTCATAtgcgtttcggacaatgctccgaaataataactctg t" /listShort="S1435, rpmEA, tdk" /GFF_Attribute="listLong" promotor_-35 complement(3668986..3668993) /Source="Nicolas_upshift_promotors" /id="U2918" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.49050949050949" /psig="0.999000999001" /xcortree=2639 /SigmaFactorBS="tatcatctgcaagaaggtaaattgTATTTGCAaaagaagtaa atcACTGATATAATTTTCTCATAtgcgtttcggacaatgctccgaaataataactctg t" /listShort="S1435, rpmEA, tdk" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3668998..3670281) /gene="rho" /locus_tag="BSU_37080" /old_locus_tag="BSU37080" /function="16.2: Construct biomass (Anabolism)" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:10027981, 16014871, 18852477, 28520932, 28723971" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10027981, 16014871, 18852477, 28520932, 28723971; Product type f: factor" /codon_start=1 /transl_table=11 /product="transcriptional terminator Rho" /protein_id="NP_391589.2" /db_xref="EnsemblGenomes-Gn:BSU37080" /db_xref="EnsemblGenomes-Tr:CAB15725" /db_xref="GOA:Q03222" /db_xref="InterPro:IPR000194" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR004665" /db_xref="InterPro:IPR011112" /db_xref="InterPro:IPR011113" /db_xref="InterPro:IPR011129" /db_xref="InterPro:IPR012340" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR036269" /db_xref="SubtiList:BG10416" /db_xref="UniProtKB/Swiss-Prot:Q03222" /translation="MKDVSISSLENMKLKELYELARHYKISYYSKLTKKELIFAILKA NAEQEDLLFMEGVLEIIQSEGFGFLRPINYSPSSEDIYISASQIRRFDLRNGDKVSGK VRPPKENERYYGLLHVEAVNGDDPESAKERVHFPALTPLYPDRQMVLETKPNFLSTRI MDMMAPVGFGQRGLIVAPPKAGKTMLLKEIANSITANQPEAELIVLLIDERPEEVTDI ERSVAGDVVSSTFDEVPENHIKVAELVLERAMRLVEHKKDVIILMDSITRLARAYNLV IPPSGRTLSGGIDPAAFHRPKRFFGAARNIEEGGSLTILATALVDTGSRMDDVIYEEF KGTGNMELHLDRSLAERRIFPAIDIRRSGTRKEELLVPKEHLDRLWSIRKTMSDSPDF AEKFMRKMKKTKTNQEFFDILNQEWKQANLSSARR*" gene complement(3668998..3670281) /gene="rho" /locus_tag="BSU_37080" /old_locus_tag="BSU37080" S_feature complement(3670282..3670584) /Source="Nicolas_S_feature" /locus_tag="new_3804684_3804986_c" /HighExp="H2O2, Cold, G135, HPh, G180, G150, LBGstat, Oxctl, Paraq, LPh" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="0.811, 1" /TUlongSig="SigH, SigA" /TUlongPSig="1, 0.997" /label="S1436" CDS complement(3670312..3670473) /locus_tag="BSU_37089" /old_locus_tag="BSU37089" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function; PubMedId : 20525796" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_009514010.1" /db_xref="EnsemblGenomes-Gn:BSU37089" /db_xref="EnsemblGenomes-Tr:CCQ48606" /db_xref="UniProtKB/TrEMBL:L8EA05" /translation="MFLSSLPSKLIKTILLTKAPIMGGSVTDRSSFMLKKECALADVV QKQQMTCSE*" gene complement(3670312..3670473) /locus_tag="BSU_37089" /old_locus_tag="BSU37089" promotor_-10 complement(3670564..3670583) /Source="Nicolas_upshift_promotors" /id="U2919" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.72027972027972" /psig="0.811188811188811" /xcortree=2485 /SigmaFactorBS="aaagcgtcaactctatcaattccgtgtcaaaaccttatttcA GTTGaataattttttgaaaTAAGGTAAAAATAAAGAGTGctgcgaattttactgcgta a" /listShort="S1436, rho, S1435, rpmEA, tdk" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3670584) /Source="Nicolas_upshifts" /id="U2919" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.72027972027972" /psig="0.811188811188811" /xcortree=2485 /SigmaFactorBS="aaagcgtcaactctatcaattccgtgtcaaaaccttatttcA GTTGaataattttttgaaaTAAGGTAAAAATAAAGAGTGctgcgaattttactgcgta a" /listShort="S1436, rho, S1435, rpmEA, tdk" /GFF_Attribute="listLong" promotor_-35 complement(3670599..3670603) /Source="Nicolas_upshift_promotors" /id="U2919" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.72027972027972" /psig="0.811188811188811" /xcortree=2485 /SigmaFactorBS="aaagcgtcaactctatcaattccgtgtcaaaaccttatttcA GTTGaataattttttgaaaTAAGGTAAAAATAAAGAGTGctgcgaattttactgcgta a" /listShort="S1436, rho, S1435, rpmEA, tdk" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3670688..3671653) /gene="glpX" /locus_tag="BSU_37090" /old_locus_tag="BSU37090" /EC_number="3.1.3.11" /function="16.11: Scavenge (Catabolism)" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:19270101" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 19270101; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="fructose 1,6-bisphosphatase class II" /protein_id="NP_391590.1" /db_xref="EnsemblGenomes-Gn:BSU37090" /db_xref="EnsemblGenomes-Tr:CAB15726" /db_xref="GOA:Q03224" /db_xref="InterPro:IPR004464" /db_xref="SubtiList:BG10415" /db_xref="UniProtKB/Swiss-Prot:Q03224" /translation="MERSLSMELVRVTEAAALASARWMGRGKKDEADEAATSAMRDVF DTVPMKGTVVIGEGEMDEAPMLYIGEKLGNGYGPRVDVAVDPLEGTNILASGGWNALT VIAVADHGTLLNAPDMYMQKIAVGPEAVGCIDIEAPVIDNLKAVAKAKNKDVEDVVAT ILNRERHAKIISELREAGARIKLINDGDVAGAINTAFDHTGVDILFGSGGAPEGVLSA VALKALGGEIIGKLLPQSEEEITRCHKMGLDLSKVLRMEDLVKGDDAIFAATGVTDGE LLKGVQFKGSVGTTESLVIRAKSGTVRFVDGRHSLKKKPNLVIRP*" gene complement(3670688..3671653) /gene="glpX" /locus_tag="BSU_37090" /old_locus_tag="BSU37090" downshifts complement(3670694) /Source="Nicolas_upshifts" /id="D1918" /incds=0 /nref=56 /ntot=196 /MaxReadThrough="5.42698" /MaxDrop="5.21817" /score="-2.15106481" /energy="-10.2" /TU="U2921,U2922" /idTUdmin="U2922" /TUdmin="-88" /isTUend="FALSE" promotor_-35 3671270..3671279 /Source="Nicolas_upshift_promotors" /id="U2920" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=1384 /SigmaFactorBS="aggtgcttcgatgtcaatgcagcccaccgcTTCCGGACCGac tgcgatttttTGCATATACATGTCAGGAGCattcagaagcgtgccatggtctgcgacc g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3671292..3671311 /Source="Nicolas_upshift_promotors" /id="U2920" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=1384 /SigmaFactorBS="aggtgcttcgatgtcaatgcagcccaccgcTTCCGGACCGac tgcgatttttTGCATATACATGTCAGGAGCattcagaagcgtgccatggtctgcgacc g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3671300 /Source="Nicolas_upshifts" /id="U2920" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=1384 /SigmaFactorBS="aggtgcttcgatgtcaatgcagcccaccgcTTCCGGACCGac tgcgatttttTGCATATACATGTCAGGAGCattcagaagcgtgccatggtctgcgacc g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" CDS complement(3671684..3672973) /gene="murAB" /locus_tag="BSU_37100" /old_locus_tag="BSU37100" /EC_number="2.5.1.7" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:14763982, 19270101" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 14763982, 19270101; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="UDP-N-acetylglucosamine 1-carboxyvinyltransferase" /protein_id="NP_391591.2" /db_xref="EnsemblGenomes-Gn:BSU37100" /db_xref="EnsemblGenomes-Tr:CAB15727" /db_xref="GOA:P19670" /db_xref="InterPro:IPR001986" /db_xref="InterPro:IPR005750" /db_xref="InterPro:IPR013792" /db_xref="InterPro:IPR036968" /db_xref="SubtiList:BG10414" /db_xref="UniProtKB/Swiss-Prot:P19670" /translation="MEKLNIAGGDSLNGTVHISGAKNSAVALIPATILANSEVTIEGL PEISDIETLRDLLKEIGGNVHFENGEMVVDPTSMISMPLPNGKVKKLRASYYLMGAML GRFKQAVIGLPGGCHLGPRPIDQHIKGFEALGAEVTNEQGAIYLRAERLRGARIYLDV VSVGATINIMLAAVLAEGKTIIENAAKEPEIIDVATLLTSMGAKIKGAGTNVIRIDGV KELHGCKHTIIPDRIEAGTFMIAGAAMGKEVIIDNVIPTHLESLTAKLREMGYHIETS DDQLLIVGGQKNLKPVDVKTLVYPGFPTDLQQPMTALLTRAKGTSVVTDTIYSARFKH IDELRRMGANMKVEGRSAIITGPVELQGAKVKASDLRAGACLVVAGLMADGVTEITGL EHIDRGYSSLEKKLEGLGATIWRERMTDEEIEQLQNS*" gene complement(3671684..3672973) /gene="murAB" /locus_tag="BSU_37100" /old_locus_tag="BSU37100" S_feature complement(3672974..3673333) /Source="Nicolas_S_feature" /locus_tag="new_3807376_3807735_c" /HighExp="dia5, Fru, UNK1, Glucon, HiOs, T-5.40H, nit, SMM, MG 120, Mal" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.16076699999999999" /TUshortSig="SigA, SigH" /TUshortPSig="1, 1" /TUlongSig="SigA" /TUlongPSig="0.997" /label="S1437" CDS complement(3673352..3673990) /gene="tal" /locus_tag="BSU_37110" /old_locus_tag="BSU37110" /EC_number="2.2.1.2" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:4275311, 12469342, 22212631, 23468065" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 4275311, 12469342, 22212631, 23468065; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="transaldolase" /protein_id="NP_391592.3" /db_xref="EnsemblGenomes-Gn:BSU37110" /db_xref="EnsemblGenomes-Tr:CAB15728" /db_xref="GOA:P19669" /db_xref="InterPro:IPR001585" /db_xref="InterPro:IPR004731" /db_xref="InterPro:IPR013785" /db_xref="InterPro:IPR018225" /db_xref="InterPro:IPR022999" /db_xref="InterPro:IPR033919" /db_xref="PDB:3R8R" /db_xref="SubtiList:BG10413" /db_xref="UniProtKB/Swiss-Prot:P19669" /translation="MLFFVDTANIDEIREANELGILAGVTTNPSLVAKEANVSFHDRL REITDVVKGSVSAEVISLKAEEMIEEGKELAKIAPNITVKIPMTSDGLKAVRALTDLG IKTNVTLIFNANQALLAARAGATYVSPFLGRLDDIGHNGLDLISEVKQIFDIHGLDTQ IIAASIRHPQHVTEAALRGAHIGTMPLKVIHALTKHPLTDKGIEQFLADWNK*" gene complement(3673352..3673990) /gene="tal" /locus_tag="BSU_37110" /old_locus_tag="BSU37110" downshifts complement(3673378) /Source="Nicolas_upshifts" /id="D1919" /incds=0 /nref=6 /ntot=65 /MaxReadThrough="6.97243" /MaxDrop="4.038" /score="-6.93331064" /energy="-18.4" /TU="U2921,U2922" /idTUdmin="U2926" /TUdmin=1716 /isTUend="FALSE" S_feature complement(3673991..3674109) /Source="Nicolas_S_feature" /locus_tag="new_3808393_3808511_c" /HighExp="dia5, LBGtran, M40t45, Lbtran, Mt0, M40t90, M0t45, Lbstat, Lbexp, M0t90" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigH" /TUshortPSig="1, 1" /TUlongSig="SigA" /TUlongPSig="0.997" /label="S1438" CDS complement(3674110..3674967) /gene="fbaA" /locus_tag="BSU_37120" /old_locus_tag="BSU37120" /EC_number="4.1.2.13" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:10559165, 10658656, 12682299, 14526031, 17420574, 18310071, 25355936" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10559165, 10658656, 12682299, 14526031, 17420574, 18310071, 25355936; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="fructose-1,6-bisphosphate aldolase" /protein_id="NP_391593.1" /db_xref="EnsemblGenomes-Gn:BSU37120" /db_xref="EnsemblGenomes-Tr:CAB15729" /db_xref="GOA:P13243" /db_xref="InterPro:IPR000771" /db_xref="InterPro:IPR011289" /db_xref="InterPro:IPR013785" /db_xref="SubtiList:BG10412" /db_xref="UniProtKB/Swiss-Prot:P13243" /translation="MPLVSMTEMLNTAKEKGYAVGQFNLNNLEFTQAILQAAEEEKSP VILGVSEGAGRYMGGFKTVVAMVKALMEEYKVTVPVAIHLDHGSSFESCAKAIHAGFT SVMIDASHHPFEENVATTAKVVELAHFHGVSVEAELGTVGGQEDDVIAEGVIYADPKE CQELVERTGIDCLAPALGSVHGPYKGEPNLGFKEMEEIGKSTGLPLVLHGGTGIPTAD IKKSISLGTAKINVNTENQISSAKAVRETLAAKPDEYDPRKYLGPAREAIKETVIGKM REFGSSNQA*" gene complement(3674110..3674967) /gene="fbaA" /locus_tag="BSU_37120" /old_locus_tag="BSU37120" S_feature complement(3674968..3675094) /Source="Nicolas_S_feature" /locus_tag="new_3809370_3809496_c" /HighExp="C90, Lbtran, LBGtran, dia5, LBGexp, aero, M0t90, Glu, Lbexp, MG 5" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigH" /TUshortPSig="1, 1" /TUlongSig="SigA" /TUlongPSig="0.997" /label="S1439" promotor_-10 complement(3675076..3675095) /Source="Nicolas_upshift_promotors" /id="U2921" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.807192807192807" /psig=1 /xcortree=2356 /SigmaFactorBS="taactgacaaaaagaagaaacaaatgaatcatgtcattATGT TGCCgatttgtcgaaaaGTTGGTATCCTAGTTATGGAgaaaaagcgatctgagtattt a" /listShort="S1439, fbaA, S1438, ywjH, S1437, murAB, ywjI, S1436, rho, S1435, rpmEA" /listLong="tdk" /label="promotor_-10" upshifts complement(3675094) /Source="Nicolas_upshifts" /id="U2921" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.807192807192807" /psig=1 /xcortree=2356 /SigmaFactorBS="taactgacaaaaagaagaaacaaatgaatcatgtcattATGT TGCCgatttgtcgaaaaGTTGGTATCCTAGTTATGGAgaaaaagcgatctgagtattt a" /listShort="S1439, fbaA, S1438, ywjH, S1437, murAB, ywjI, S1436, rho, S1435, rpmEA" /listLong="tdk" promotor_-35 complement(3675109..3675116) /Source="Nicolas_upshift_promotors" /id="U2921" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.807192807192807" /psig=1 /xcortree=2356 /SigmaFactorBS="taactgacaaaaagaagaaacaaatgaatcatgtcattATGT TGCCgatttgtcgaaaaGTTGGTATCCTAGTTATGGAgaaaaagcgatctgagtattt a" /listShort="S1439, fbaA, S1438, ywjH, S1437, murAB, ywjI, S1436, rho, S1435, rpmEA" /listLong="tdk" /label="promotor_-35" CDS complement(3675148..3675522) /gene="spo0F" /locus_tag="BSU_37130" /old_locus_tag="BSU37130" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:8257105, 11934609, 16788205, 17350627, 19004019, 19040634, 20413551, 22267516, 25256619, 26055117, 27543719" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8257105, 11934609, 16788205, 17350627, 19004019, 19040634, 20413551, 22267516, 25256619, 26055117, 27543719; Product type r : regulator" /codon_start=1 /transl_table=11 /product="two-component response regulator of sporulation initiation" /protein_id="NP_391594.1" /db_xref="EnsemblGenomes-Gn:BSU37130" /db_xref="EnsemblGenomes-Tr:CAB15730" /db_xref="GOA:P06628" /db_xref="InterPro:IPR001789" /db_xref="InterPro:IPR011006" /db_xref="PDB:1F51" /db_xref="PDB:1FSP" /db_xref="PDB:1NAT" /db_xref="PDB:1PEY" /db_xref="PDB:1PUX" /db_xref="PDB:1SRR" /db_xref="PDB:2FSP" /db_xref="PDB:2FTK" /db_xref="PDB:2JVI" /db_xref="PDB:2JVJ" /db_xref="PDB:2JVK" /db_xref="PDB:3Q15" /db_xref="SubtiList:BG10411" /db_xref="UniProtKB/Swiss-Prot:P06628" /translation="MMNEKILIVDDQYGIRILLNEVFNKEGYQTFQAANGLQALDIVT KERPDLVLLDMKIPGMDGIEILKRMKVIDENIRVIIMTAYGELDMIQESKELGALTHF AKPFDIDEIRDAVKKYLPLKSN*" gene complement(3675148..3675522) /gene="spo0F" /locus_tag="BSU_37130" /old_locus_tag="BSU37130" promotor_-10 complement(3675562..3675580) /Source="Nicolas_upshift_promotors" /id="U2922" /multdbtbs="SigH" /comp="M1" /sig="SigH" /pcomp=1 /psig=1 /xcortree=533 /SigmaFactorBS="atgctcagaaaatgtcgtaaagtagactattataattAAAGG AAATaggaaaatcaAACAGAATACATACAATACtgcttacttttgacgaaaatcataa t" /listShort="spo0F, S1439, fbaA, S1438, ywjH, S1437, murAB, ywjI" /listLong="S1436, rho, S1435, rpmEA, tdk" /label="promotor_-10" upshifts complement(3675576) /Source="Nicolas_upshifts" /id="U2922" /multdbtbs="SigH" /comp="M1" /sig="SigH" /pcomp=1 /psig=1 /xcortree=533 /SigmaFactorBS="atgctcagaaaatgtcgtaaagtagactattataattAAAGG AAATaggaaaatcaAACAGAATACATACAATACtgcttacttttgacgaaaatcataa t" /listShort="spo0F, S1439, fbaA, S1438, ywjH, S1437, murAB, ywjI" /listLong="S1436, rho, S1435, rpmEA, tdk" S_feature complement(3675578..3676217) /Source="Nicolas_S_feature" /locus_tag="new_3809980_3810619_c" /HighExp="dia15, Diami, dia5, G135, Etha, G150, G180, Salt, H2O2, Paraq" /AntisenseName="ywjG" /AntisenseCor="0.58536525532649697" /AntisenseRegPval="-25.4" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.997" /TUlongSig="NA" /TUlongPSig="NA" /label="S1440" promotor_-35 3675579..3675582 /Source="Nicolas_upshift_promotors" /id="U2923" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.456543456543457" /psig=1 /xcortree=2539 /SigmaFactorBS="aaaagtaagcagtattgtatgtattctgTTTGattttcctat ttcctTTAATTATAATAGTCTACTTtacgacattttctgagcattttctcttttgttg t" /listShort="ywjG" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 complement(3675591..3675599) /Source="Nicolas_upshift_promotors" /id="U2922" /multdbtbs="SigH" /comp="M1" /sig="SigH" /pcomp=1 /psig=1 /xcortree=533 /SigmaFactorBS="atgctcagaaaatgtcgtaaagtagactattataattAAAGG AAATaggaaaatcaAACAGAATACATACAATACtgcttacttttgacgaaaatcataa t" /listShort="spo0F, S1439, fbaA, S1438, ywjH, S1437, murAB, ywjI" /listLong="S1436, rho, S1435, rpmEA, tdk" /label="promotor_-35" promotor_-10 3675598..3675617 /Source="Nicolas_upshift_promotors" /id="U2923" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.456543456543457" /psig=1 /xcortree=2539 /SigmaFactorBS="aaaagtaagcagtattgtatgtattctgTTTGattttcctat ttcctTTAATTATAATAGTCTACTTtacgacattttctgagcattttctcttttgttg t" /listShort="ywjG" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3675611 /Source="Nicolas_upshifts" /id="U2923" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.456543456543457" /psig=1 /xcortree=2539 /SigmaFactorBS="aaaagtaagcagtattgtatgtattctgTTTGattttcctat ttcctTTAATTATAATAGTCTACTTtacgacattttctgagcattttctcttttgttg t" /listShort="ywjG" /GFF_Attribute="listLong" promotor_-35 3675625..3675630 /Source="Nicolas_upshift_promotors" /id="U2924" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.626373626373626" /psig="0.977022977022977" /xcortree=1775 /SigmaFactorBS="ctttaattataatagtctactttacgacaTTTTCTgagcatt ttctctttTGTTGTATACTGATATTGTAcgttataaaggaggattcacttatgttgaa a" /listShort="ywjG" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3675646..3675665 /Source="Nicolas_upshift_promotors" /id="U2924" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.626373626373626" /psig="0.977022977022977" /xcortree=1775 /SigmaFactorBS="ctttaattataatagtctactttacgacaTTTTCTgagcatt ttctctttTGTTGTATACTGATATTGTAcgttataaaggaggattcacttatgttgaa a" /listShort="ywjG" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3675656 /Source="Nicolas_upshifts" /id="U2924" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.626373626373626" /psig="0.977022977022977" /xcortree=1775 /SigmaFactorBS="ctttaattataatagtctactttacgacaTTTTCTgagcatt ttctctttTGTTGTATACTGATATTGTAcgttataaaggaggattcacttatgttgaa a" /listShort="ywjG" /GFF_Attribute="listLong" CDS 3675688..3676209 /gene="ywjG" /locus_tag="BSU_37140" /old_locus_tag="BSU37140" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_391595.1" /db_xref="EnsemblGenomes-Gn:BSU37140" /db_xref="EnsemblGenomes-Tr:CAB15731" /db_xref="InterPro:IPR019676" /db_xref="SubtiList:BG11053" /db_xref="UniProtKB/Swiss-Prot:P06629" /translation="MLKIFTTQLTGIFSRIQDKESDAIEDGARLLAQAVISGHSIYLY GANELQGVFYEATESKEPFPSVKAFPENAEEVTESDRVLMFCSGTGTAEEQELAKELY EKGAGVVCVSPAAKDSAGIEQYCDVHIDSKLKMPLVPDEDGTRYGFPSLMTALYVYHA LSFTLKEILQEYA*" gene 3675688..3676209 /gene="ywjG" /locus_tag="BSU_37140" /old_locus_tag="BSU37140" promotor_-35 3676152..3676155 /Source="Nicolas_upshift_promotors" /id="U2925" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.936063936063936" /psig="0.99000999000999" /xcortree=1781 /SigmaFactorBS="acgggtttccctctttaatgacagcactGTATgtctatcacg ctttATCGTTTACACTAAAAGAAAttctgcaagagtatgcataatatcttattgtaca t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3676170..3676189 /Source="Nicolas_upshift_promotors" /id="U2925" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.936063936063936" /psig="0.99000999000999" /xcortree=1781 /SigmaFactorBS="acgggtttccctctttaatgacagcactGTATgtctatcacg ctttATCGTTTACACTAAAAGAAAttctgcaagagtatgcataatatcttattgtaca t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3676184 /Source="Nicolas_upshifts" /id="U2925" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.936063936063936" /psig="0.99000999000999" /xcortree=1781 /SigmaFactorBS="acgggtttccctctttaatgacagcactGTATgtctatcacg ctttATCGTTTACACTAAAAGAAAttctgcaagagtatgcataatatcttattgtaca t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 complement(3676207..3676226) /Source="Nicolas_upshift_promotors" /id="U2926" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.705294705294705" /psig="0.997002997002997" /xcortree=1956 /SigmaFactorBS="ccgtttgtcaaaagcgggcaagtctttttTATTTGTTtccgg caagttccaGCATGTACAATAAGATATTAtgcatactcttgcagaatttcttttagtg t" /listShort="S1440, spo0F" /listLong="S1439, fbaA, S1438, ywjH, S1437, murAB, ywjI, S1436, rho, S1435, rpmEA, tdk" /label="promotor_-10" upshifts complement(3676217) /Source="Nicolas_upshifts" /id="U2926" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.705294705294705" /psig="0.997002997002997" /xcortree=1956 /SigmaFactorBS="ccgtttgtcaaaagcgggcaagtctttttTATTTGTTtccgg caagttccaGCATGTACAATAAGATATTAtgcatactcttgcagaatttcttttagtg t" /listShort="S1440, spo0F" /listLong="S1439, fbaA, S1438, ywjH, S1437, murAB, ywjI, S1436, rho, S1435, rpmEA, tdk" downshifts 3676228 /Source="Nicolas_upshifts" /id="D1920" /incds=0 /nref=191 /ntot=242 /MaxReadThrough="1.98527" /MaxDrop="5.8354" /score="11.5531593" /energy="-11.9" /TU="NA" /idTUdmin="U2923" /TUdmin=0 /isTUend="TRUE" promotor_-35 complement(3676241..3676248) /Source="Nicolas_upshift_promotors" /id="U2926" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.705294705294705" /psig="0.997002997002997" /xcortree=1956 /SigmaFactorBS="ccgtttgtcaaaagcgggcaagtctttttTATTTGTTtccgg caagttccaGCATGTACAATAAGATATTAtgcatactcttgcagaatttcttttagtg t" /listShort="S1440, spo0F" /listLong="S1439, fbaA, S1438, ywjH, S1437, murAB, ywjI, S1436, rho, S1435, rpmEA, tdk" /label="promotor_-35" CDS complement(3676291..3677898) /gene="pyrG" /locus_tag="BSU_37150" /old_locus_tag="BSU37150" /EC_number="6.3.4.2" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:11544212, 15252202, 17158658, 17302819" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11544212, 15252202, 17158658, 17302819; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="CTP synthetase" /protein_id="NP_391596.1" /db_xref="EnsemblGenomes-Gn:BSU37150" /db_xref="EnsemblGenomes-Tr:CAB15743" /db_xref="GOA:P13242" /db_xref="InterPro:IPR004468" /db_xref="InterPro:IPR017456" /db_xref="InterPro:IPR017926" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR029062" /db_xref="InterPro:IPR033828" /db_xref="SubtiList:BG10410" /db_xref="UniProtKB/Swiss-Prot:P13242" /translation="MTKYIFVTGGVVSSLGKGIVAASLGRLLKNRGLNVTIQKFDPYI NVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKFSNVTTGKIYSTVLKKE RRGDYLGGTVQVIPHITNELKDRVYRAGKETNADVVITEIGGTVGDIESLPFLEAIRQ MKSDIGRENVMYIHCTLVPYIKAAGELKTKPTQHSVKELRSLGIQPNIIVVRTEMPIS QDMKDKIALFCDIDTKAVIECEDADNLYSIPLELQKQGLDKLVCEHMKLACKEAEMSE WKELVNKVSNLSQTITIGLVGKYVELPDAYISVVESLRHAGYAFDTDVKVKWINAEEV TENNIAELTSGTDGIIVPGGFGDRGVEGKIVATKYARENNIPFLGICLGMQVASIEYA RNVLGLKGAHSAEIDPSTQYPIIDLLPEQKDVEDLGGTLRLGLYPCKLEEGTKAFEVY QDEVVYERHRHRYEFNNEFRQQMEEQGFVFSGTSPDGRLVEIIELKDHPWFVASQFHP EFKSRPTRPQPLFKGFIGASVEAANQK*" gene complement(3676291..3677898) /gene="pyrG" /locus_tag="BSU_37150" /old_locus_tag="BSU37150" downshifts complement(3676304) /Source="Nicolas_upshifts" /id="D1921" /incds=0 /nref=222 /ntot=259 /MaxReadThrough="2.2929" /MaxDrop="8.17874" /score="18.9699606" /energy="-12.1" /TU="NA" /idTUdmin="U2927" /TUdmin=0 /isTUend="TRUE" S_feature complement(3677899..3678086) /Source="Nicolas_S_feature" /locus_tag="new_3812301_3812488_c" /HighExp="LBGexp, Lbexp, dia0, G150, G135, G180, Paraq, Oxctl, dia15, LBGtran" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA, SigA" /TUshortPSig="0.999, 0.999, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S1441" promotor_-10 complement(3678074..3678093) /Source="Nicolas_upshift_promotors" /id="U2927" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.586413586413586" /psig="0.999000999001" /xcortree=2660 /SigmaFactorBS="taaatagtatcagatttcatcttcaaaacgaTCTTGACTttc atagtcgaactATGTAGTATGTATTTTGGGCtcttcaaaaacgaagagagaacatagt a" /listShort="S1441, pyrG" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3678086) /Source="Nicolas_upshifts" /id="U2927" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.586413586413586" /psig="0.999000999001" /xcortree=2660 /SigmaFactorBS="taaatagtatcagatttcatcttcaaaacgaTCTTGACTttc atagtcgaactATGTAGTATGTATTTTGGGCtcttcaaaaacgaagagagaacatagt a" /listShort="S1441, pyrG" /GFF_Attribute="listLong" promotor_-35 complement(3678108..3678115) /Source="Nicolas_upshift_promotors" /id="U2927" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.586413586413586" /psig="0.999000999001" /xcortree=2660 /SigmaFactorBS="taaatagtatcagatttcatcttcaaaacgaTCTTGACTttc atagtcgaactATGTAGTATGTATTTTGGGCtcttcaaaaacgaagagagaacatagt a" /listShort="S1441, pyrG" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3678140..3678661) /gene="rpoE" /locus_tag="BSU_37160" /old_locus_tag="BSU37160" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:189250, 9795209, 10336502, 10438769, 10672039, 10910724, 11029421, 23543716, 26546673, 27679485" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 189250, 9795209, 10336502, 10438769, 10672039, 10910724, 11029421, 23543716, 26546673, 27679485; Product type f: factor" /codon_start=1 /transl_table=11 /product="RNA polymerase (delta subunit) and transcriptional repressor" /protein_id="NP_391597.1" /db_xref="EnsemblGenomes-Gn:BSU37160" /db_xref="EnsemblGenomes-Tr:CAB15744" /db_xref="GOA:P12464" /db_xref="InterPro:IPR007759" /db_xref="InterPro:IPR029757" /db_xref="PDB:2KRC" /db_xref="PDB:2M4K" /db_xref="PDB:4NC7" /db_xref="PDB:4NC8" /db_xref="SubtiList:BG10409" /db_xref="UniProtKB/Swiss-Prot:P12464" /translation="MGIKQYSQEELKEMALVEIAHELFEEHKKPVPFQELLNEIASLL GVKKEELGDRIAQFYTDLNIDGRFLALSDQTWGLRSWYPYDQLDEETQPTVKAKKKKA KKAVEEDLDLDEFEEIDEDDLDLDEVEEELDLEADDFDEEDLDEDDDDLEIEEDIIDE DDEDYDDEEEEIK*" gene complement(3678140..3678661) /gene="rpoE" /locus_tag="BSU_37160" /old_locus_tag="BSU37160" downshifts complement(3678196) /Source="Nicolas_upshifts" /id="D1922" /incds=0 /nref=7 /ntot=182 /MaxReadThrough="6.49215" /MaxDrop="3.2129" /score="19.8764263" /energy="-19.4" /TU="U2928,U2929" /idTUdmin="U2927" /TUdmin="-1892" /isTUend="FALSE" S_feature complement(3678662..3678764) /Source="Nicolas_S_feature" /locus_tag="new_3813064_3813166_c" /HighExp="H2O2, Paraq, Oxctl, LBGexp, G180, dia15, dia0, Lbexp, BMM, Heat" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="0.999, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S1442" promotor_-10 complement(3678745..3678764) /Source="Nicolas_upshift_promotors" /id="U2928" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.954045954045954" /psig="0.999000999001" /xcortree=2550 /SigmaFactorBS="ggatcactcttgtaaaattatttaaattaacgctgttaaggG TAGcatattctgttttatTTTGTTTATAATGAGAGGTAtggtttgtataagaacgata c" /listShort="S1442, rpoE, S1441, pyrG" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3678764) /Source="Nicolas_upshifts" /id="U2928" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.954045954045954" /psig="0.999000999001" /xcortree=2550 /SigmaFactorBS="ggatcactcttgtaaaattatttaaattaacgctgttaaggG TAGcatattctgttttatTTTGTTTATAATGAGAGGTAtggtttgtataagaacgata c" /listShort="S1442, rpoE, S1441, pyrG" /GFF_Attribute="listLong" S_feature complement(3678766..3678843) /Source="Nicolas_S_feature" /locus_tag="new_3813168_3813245_c" /HighExp="T0.30H, S8, S7, S6, S4, S3, S5, Sw, BC, Lbstat" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1443" promotor_-35 complement(3678780..3678783) /Source="Nicolas_upshift_promotors" /id="U2928" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.954045954045954" /psig="0.999000999001" /xcortree=2550 /SigmaFactorBS="ggatcactcttgtaaaattatttaaattaacgctgttaaggG TAGcatattctgttttatTTTGTTTATAATGAGAGGTAtggtttgtataagaacgata c" /listShort="S1442, rpoE, S1441, pyrG" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3678844..3679983) /gene="acdA" /locus_tag="BSU_37170" /old_locus_tag="BSU37170" /EC_number="1.3.99.-" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:17189250, 21398533" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 17189250, 21398533; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="acyl-CoA dehydrogenase" /protein_id="NP_391598.1" /db_xref="EnsemblGenomes-Gn:BSU37170" /db_xref="EnsemblGenomes-Tr:CAB15745" /db_xref="GOA:P45867" /db_xref="InterPro:IPR006089" /db_xref="InterPro:IPR006091" /db_xref="InterPro:IPR009075" /db_xref="InterPro:IPR009100" /db_xref="InterPro:IPR013786" /db_xref="InterPro:IPR036250" /db_xref="InterPro:IPR037069" /db_xref="SubtiList:BG11239" /db_xref="UniProtKB/Swiss-Prot:P45867" /translation="MNFSLSEEHEMIRKLVRDFAKHEVAPTAAERDEQERFDRELFRE MANLGLTGIPWPEDYGGIGSDYLAYVIAVEELSKVCASTGVTLSAHISLCSWPLFAFG TEEQKTEYLTQLALGEKIGAFALTEAGSGSDAGSMKTTAERIGDDYVLNGSKVFITNG GVADIYIVFAVTDPEKKKKGVTAFIVEKDFEGFFTGKKEKKLGIRSSPTTEIMFEDCV VPASKRLGEEGEGFKIAMKTLDGGRNGIAAQAVGIAQGALDAALQYAKERKQFGKSIA EQQGIAFKLADMATMIEASRLLTYQAAWLESSGLPYGKASAMSKLMAGDTAMKVTTEA VQIFGGYGYTKDYPVERYMRDAKITQIYEGTQEIQRLVISRMLAD*" gene complement(3678844..3679983) /gene="acdA" /locus_tag="BSU_37170" /old_locus_tag="BSU37170" CDS complement(3679980..3682097) /gene="fadF" /locus_tag="BSU_37180" /old_locus_tag="BSU37180" /EC_number="1.-.-.-" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 17189250, 21398533; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative iron-sulphur-binding reductase" /protein_id="NP_391599.1" /db_xref="EnsemblGenomes-Gn:BSU37180" /db_xref="EnsemblGenomes-Tr:CAB15746" /db_xref="GOA:P45866" /db_xref="InterPro:IPR004017" /db_xref="InterPro:IPR009051" /db_xref="InterPro:IPR017896" /db_xref="InterPro:IPR017900" /db_xref="InterPro:IPR036197" /db_xref="SubtiList:BG11311" /db_xref="UniProtKB/Swiss-Prot:P45866" /translation="MSGFLIANALLFLIVTAYAVYLFVYLVKTRLAYIKLGQKEQFDQ RFKERLHAIWVNVFGQKKLLKDKKSGIIHVMFFYGFILVQFGAIDFIIKGLAPGRNLS LGPVYPAFTFFQEIVTFLILIAVGWAFYRRYIEKLVRLKRGFKAGLVLIFIGGLMLTV LLGNGMNLIWHEHGLSWSEPIASGIAFMLSGVGKTGAAVIFYIAWWIHLLFLLSFLVY VPQSKHAHLIAGPANVFFNRMESAGKLEKIDFTDETKESYGAGKIEDFRQSQLLDLYA CVECGRCTNMCPATGTGKMLSPMDLILRLRDHLTEKGAAVTSRSPWVPAAAFRHTRGN QLAAASAGSGSQEAAAALDYNPSLIGDVITEEEIWACTTCRNCEDQCPVMNEHVDKII DLRRYLVLTEGKMDSDAQRAMTSIERQGNPWGLNRKERENWRDEAPDAEIPTVKEMKK EGKEFEYLFWVGSMGSYDNRSQKIAISFAKLLNHAGVSFAILGNKEKNSGDTPRRLGN EFLFQELAEKNISEFEKNDVKKIVTIDPHAYNLFKNEYPDFGFEGEVYHHTEVLAELV KNGKLRPQHPLHETITFHDSCYLGRYNEVYDPPREILKAIPGVQLVEMERSRETGMCC GAGGGLMWMEEETGNRINVARTEQALAVNPSVISSGCPYCLTMLGDGTKAKEAEDQVK TYDVVELLAQSVLGADLKMGEKQ*" gene complement(3679980..3682097) /gene="fadF" /locus_tag="BSU_37180" /old_locus_tag="BSU37180" S_feature complement(3682098..3682156) /Source="Nicolas_S_feature" /locus_tag="new_3816500_3816558_c" /HighExp="T0.30H, S6, BC, S8, S7, Sw, S5, S4, Lbstat, B60" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1444" promotor_-10 complement(3682157..3682176) /Source="Nicolas_upshift_promotors" /id="U2929" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.526473526473527" /psig=1 /xcortree=373 /SigmaFactorBS="aaaggtagtgtgcccgaacagcaggaatttaatTATTGACTg aacactcattcaTTATTTATCATAAAGATAATcttatacagattcgggggtaggggat c" /listShort="S1444, fadF, acdA, S1443, S1442, rpoE, S1441, pyrG" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3682170) /Source="Nicolas_upshifts" /id="U2929" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.526473526473527" /psig=1 /xcortree=373 /SigmaFactorBS="aaaggtagtgtgcccgaacagcaggaatttaatTATTGACTg aacactcattcaTTATTTATCATAAAGATAATcttatacagattcgggggtaggggat c" /listShort="S1444, fadF, acdA, S1443, S1442, rpoE, S1441, pyrG" /GFF_Attribute="listLong" promotor_-35 complement(3682190..3682197) /Source="Nicolas_upshift_promotors" /id="U2929" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.526473526473527" /psig=1 /xcortree=373 /SigmaFactorBS="aaaggtagtgtgcccgaacagcaggaatttaatTATTGACTg aacactcattcaTTATTTATCATAAAGATAATcttatacagattcgggggtaggggat c" /listShort="S1444, fadF, acdA, S1443, S1442, rpoE, S1441, pyrG" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 3682196..3682202 /Source="Nicolas_upshift_promotors" /id="U2930" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=886 /SigmaFactorBS="tctttatgataaataatgaatgagtgttcagtcaaTAATTAA attcctgctgttcGGGCACACTACCtttactacggaaaggagtgccggtatgaaggta t" /listShort="clsB, ywjD, ywjC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3682216..3682227 /Source="Nicolas_upshift_promotors" /id="U2930" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=886 /SigmaFactorBS="tctttatgataaataatgaatgagtgttcagtcaaTAATTAA attcctgctgttcGGGCACACTACCtttactacggaaaggagtgccggtatgaaggta t" /listShort="clsB, ywjD, ywjC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3682221 /Source="Nicolas_upshifts" /id="U2930" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=886 /SigmaFactorBS="tctttatgataaataatgaatgagtgttcagtcaaTAATTAA attcctgctgttcGGGCACACTACCtttactacggaaaggagtgccggtatgaaggta t" /listShort="clsB, ywjD, ywjC" /GFF_Attribute="listLong" CDS 3682252..3683448 /gene="clsB" /locus_tag="BSU_37190" /old_locus_tag="BSU37190" /EC_number="2.7.8.-" /function="16.8: Protect" /function="16.13: Shape" /function="16.6: Maintain" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:14973018, 16514141, 18820022" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 14973018, 16514141, 18820022; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="minor cardiolipin synthetase (phospholipase D family)" /protein_id="NP_391600.1" /db_xref="EnsemblGenomes-Gn:BSU37190" /db_xref="EnsemblGenomes-Tr:CAB15747" /db_xref="GOA:P45865" /db_xref="InterPro:IPR001736" /db_xref="InterPro:IPR022924" /db_xref="InterPro:IPR025202" /db_xref="SubtiList:BG11310" /db_xref="UniProtKB/Swiss-Prot:P45865" /translation="MKVFIVIMIIVVIFFALILLDIFMGRAGYRKKAYEPVFSKKKSD IELIHCGADLVERMMNDIRQAASSVHMMFFIMKNDEVSHNMYTLLKTKAQAGVSVYLL LDWAGCRAIKKTALQTMKNAGVHVHVMNRPRFPFFFFHMQKRNHRKITVIDGKIGYIG GFNIAEEYLGKKAKFGNWEDYHLRMIGEGVHDLQTLFASDLKRNTGIELGSDVWPKLQ QGTISHKIYATDGYSLENIYLANIAQAKNRLTVCTPYYIPSKPLQEALINARKNGVSV RIIVPMKSDHPLVREAAFTYYSELLDAGCLIYRYYQGFYHVKALIIDDHLSIIGTANF DKRSLFLNEEVNVEIDDEAFTSEVYATIEEDMKKSELLTMEDFSKRTFRQRPAEWLGR ALSYFL*" gene 3682252..3683448 /gene="clsB" /locus_tag="BSU_37190" /old_locus_tag="BSU37190" S_feature complement(3682444..3683322) /Source="Nicolas_S_feature" /locus_tag="new_3816846_3817724_c" /HighExp="S4, S5, S3, S6, S7, S8, BT, B36, LoTm, B60" /AntisenseName="clsB" /AntisenseCor="0.84883232203587" /AntisenseRegPval="-75.2" /CDS_PredictionProba="NA" /TUshortSig="SigEF" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S1445" promotor_-10 complement(3683312..3683330) /Source="Nicolas_upshift_promotors" /id="U2931" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1122 /SigmaFactorBS="tgaaatcctccatcgtcagcagctccgactttTTCATAtcct cctcaattgtgGCATAGACTTCACTTGTAAacgcttcgtcatcaatttcaacattcac c" /listShort="S1445" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3683323) /Source="Nicolas_upshifts" /id="U2931" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1122 /SigmaFactorBS="tgaaatcctccatcgtcagcagctccgactttTTCATAtcct cctcaattgtgGCATAGACTTCACTTGTAAacgcttcgtcatcaatttcaacattcac c" /listShort="S1445" /GFF_Attribute="listLong" promotor_-35 complement(3683346..3683351) /Source="Nicolas_upshift_promotors" /id="U2931" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1122 /SigmaFactorBS="tgaaatcctccatcgtcagcagctccgactttTTCATAtcct cctcaattgtgGCATAGACTTCACTTGTAAacgcttcgtcatcaatttcaacattcac c" /listShort="S1445" /GFF_Attribute="listLong" /label="promotor_-35" CDS 3683461..3684423 /gene="uvsE" /locus_tag="BSU_37200" /old_locus_tag="BSU37200" /EC_number="3.-.-.-" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:8614629, 22961846" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8614629, 22961846; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="UV DNA damage repair endonuclease" /protein_id="NP_391601.1" /db_xref="EnsemblGenomes-Gn:BSU37200" /db_xref="EnsemblGenomes-Tr:CAB15748" /db_xref="GOA:P45864" /db_xref="InterPro:IPR004601" /db_xref="InterPro:IPR023520" /db_xref="InterPro:IPR036237" /db_xref="SubtiList:BG11309" /db_xref="UniProtKB/Swiss-Prot:P45864" /translation="MIFRFGFVSNAMSLWDASPAKTLTFARYSKLSKTERKEALLTVT KANLRNTMRTLHYIIGHGIPLYRFSSSIVPLATHPDVMWDFVTPFQKEFREIGELVKT HQLRTSFHPNQFTLFTSPKESVTKNAVTDMAYHYRMLEAMGIADRSVINIHIGGAYGN KDTATAQFHQNIKQLPQEIKERMTLENDDKTYTTEETLQVCEQEDVPFVFDFHHFYAN PDDHADLNVALPRMIKTWERIGLQPKVHLSSPKSEQAIRSHADYVDANFLLPLLERFR QWGTNIDFMIEAKQKDKALLRLMDELSSIRGVKRIGGGALQWKS*" gene 3683461..3684423 /gene="uvsE" /locus_tag="BSU_37200" /old_locus_tag="BSU37200" promotor_-35 3684437..3684443 /Source="Nicolas_upshift_promotors" /id="U2932" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=217 /SigmaFactorBS="gcggtgcgctgcaatggaagtcataaatgtgcaaaaataGGT TTACgacttgtcagctttGGGAACTTAGGCTATATAAgacaacaatcgatggaggaga a" /listShort="ywjC, S1446" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3684458..3684476 /Source="Nicolas_upshift_promotors" /id="U2932" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=217 /SigmaFactorBS="gcggtgcgctgcaatggaagtcataaatgtgcaaaaataGGT TTACgacttgtcagctttGGGAACTTAGGCTATATAAgacaacaatcgatggaggaga a" /listShort="ywjC, S1446" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3684458 /Source="Nicolas_upshifts" /id="U2932" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=217 /SigmaFactorBS="gcggtgcgctgcaatggaagtcataaatgtgcaaaaataGGT TTACgacttgtcagctttGGGAACTTAGGCTATATAAgacaacaatcgatggaggaga a" /listShort="ywjC, S1446" /GFF_Attribute="listLong" CDS 3684504..3684776 /gene="ywjC" /locus_tag="BSU_37210" /old_locus_tag="BSU37210" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_391602.1" /db_xref="EnsemblGenomes-Gn:BSU37210" /db_xref="EnsemblGenomes-Tr:CAB15749" /db_xref="InterPro:IPR035895" /db_xref="SubtiList:BG11308" /db_xref="UniProtKB/Swiss-Prot:P45863" /translation="MKNIKSLKVAAQAFTLRNLIHLYKMCHSGSHEVYIYSKKTMCKI KSLIELETFRMAHNEKEYLIVVEGTKASQLIEKFQNLIEPAEREAL*" gene 3684504..3684776 /gene="ywjC" /locus_tag="BSU_37210" /old_locus_tag="BSU37210" downshifts complement(3684510) /Source="Nicolas_upshifts" /id="D1923" /incds=0 /nref=4 /ntot=17 /MaxReadThrough="1.03516" /MaxDrop="5.08765" /score="17.8471239" /energy="-10" /TU="NA" /idTUdmin="U2933" /TUdmin=330 /isTUend="FALSE" downshifts 3684766 /Source="Nicolas_upshifts" /id="D1924" /incds=0 /nref=54 /ntot=128 /MaxReadThrough="4.49396" /MaxDrop="7.49636" /score="14.0189582" /energy="-10" /TU="U2932" /idTUdmin="U2930" /TUdmin=178 /isTUend="FALSE" S_feature 3684811..3685217 /Source="Nicolas_S_feature" /locus_tag="new_3819213_3819619" /HighExp="Etha, C30, Sw, Gly, C90, M/G, BC, Salt, Fru, G135" /AntisenseName="ywjB" /AntisenseCor="0.2646821361217" /AntisenseRegPval="-5" /CDS_PredictionProba="NA" /TUshortSig="SigB" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1446" CDS complement(3684818..3685342) /gene="ywjB" /locus_tag="BSU_37220" /old_locus_tag="BSU37220" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 12354229, 27795321; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative oxidoreductase" /protein_id="NP_391603.1" /db_xref="EnsemblGenomes-Gn:BSU37220" /db_xref="EnsemblGenomes-Tr:CAB15750" /db_xref="GOA:P45862" /db_xref="InterPro:IPR002734" /db_xref="InterPro:IPR024072" /db_xref="SubtiList:BG11307" /db_xref="UniProtKB/Swiss-Prot:P45862" /translation="MERKTVLYIAVSLDGMIAKEDGSIDWLDEFEGEGDNGYSDFYQT VDTVILGRSTYEHVKVLTPVFPYQDKTCYVFTGSPDSYQDEHVTFINEGARAFTARLK QEKGSNIWIAGGAELVNDFMKEDAIDEFIITVIPVVLGSGIPLFHELTNETKLRLKGT KQFGQAVQLHYVRA*" gene complement(3684818..3685342) /gene="ywjB" /locus_tag="BSU_37220" /old_locus_tag="BSU37220" downshifts complement(3684840) /Source="Nicolas_upshifts" /id="D1925" /incds=0 /nref=194 /ntot=239 /MaxReadThrough="1.38978" /MaxDrop="6.19859" /score="17.8471239" /energy="-10" /TU="NA" /idTUdmin="U2933" /TUdmin=0 /isTUend="TRUE" CDS complement(3685352..3687079) /gene="ywjA" /locus_tag="BSU_37230" /old_locus_tag="BSU37230" /EC_number="3.6.3.-" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 12119303, 12354229, 25652542; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative ABC lipid transporter (ATP-binding protein)" /protein_id="NP_391604.1" /db_xref="EnsemblGenomes-Gn:BSU37230" /db_xref="EnsemblGenomes-Tr:CAB15751" /db_xref="GOA:P45861" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR011527" /db_xref="InterPro:IPR017871" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR036640" /db_xref="SubtiList:BG11306" /db_xref="UniProtKB/Swiss-Prot:P45861" /translation="MLRQFFSYYKPYKTLFFLDFFSAIAGGLMELSFPLIVNYFIDTL LPGRDWGLIIATSIGLFAVYALSSALQYIVTYWGHMLGINIETDMRKSLFDHLQKLSF KFYDNNKTGTLMSKLTNDLMYIGEVAHHGPEDLFIAVMTILGAFGVMLFINWQLALLT FIIMPIVIWLALYFNKKMTKAFTTLNKDIGDFSARVENNIGGIRLVQAFGNEAFEKER FAVNNQRFRVTKLSSYKIMAKNGSISYMLTRFVTLFVLLCGTWFVIRGSLSYGEFVAF VLLTNVLFRPIDKINAIIEMYPRGIAGFKSYMELMETEPDIQDSPDSKDVSGLKGNIR YKHVSFGYDDHHNVLNDINLSIQAGETVAFVGPSGAGKSTLCSLLPRFYEASEGDITI DGISIKDMTLSSLRGQIGVVQQDVFLFSGTLRENIAYGRLGASEEDIWQAVKQAHLEE LVHNMPDGLDTMIGERGVKLSGGQKQRLSIARMFLKNPSILILDEATSALDTETEAAI QKALQELSEGRTTLVIAHRLATIKDADRIVVVTNNGIEEQGRHQDLIEAGGLYSRLHQ AQFGQMVHR*" gene complement(3685352..3687079) /gene="ywjA" /locus_tag="BSU_37230" /old_locus_tag="BSU37230" promotor_-10 complement(3687113..3687132) /Source="Nicolas_upshift_promotors" /id="U2933" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.397602397602398" /psig="0.999000999001" /xcortree=2106 /SigmaFactorBS="tgttttcaggtgttctgtaagaaaaaagaaatctgATCTTAC aaaacagcccgtgTATAGTATAATTGAGAAATAttatcagttatttatacattggggg a" /listShort="ywjA, ywjB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3687127) /Source="Nicolas_upshifts" /id="U2933" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.397602397602398" /psig="0.999000999001" /xcortree=2106 /SigmaFactorBS="tgttttcaggtgttctgtaagaaaaaagaaatctgATCTTAC aaaacagcccgtgTATAGTATAATTGAGAAATAttatcagttatttatacattggggg a" /listShort="ywjA, ywjB" /GFF_Attribute="listLong" promotor_-35 complement(3687146..3687152) /Source="Nicolas_upshift_promotors" /id="U2933" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.397602397602398" /psig="0.999000999001" /xcortree=2106 /SigmaFactorBS="tgttttcaggtgttctgtaagaaaaaagaaatctgATCTTAC aaaacagcccgtgTATAGTATAATTGAGAAATAttatcagttatttatacattggggg a" /listShort="ywjA, ywjB" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3687168..3688670) /gene="clsC" /locus_tag="BSU_37240" /old_locus_tag="BSU37240" /EC_number="2.7.8.-" /function="16.2: Construct biomass (Anabolism)" /function="16.6: Maintain" /function="16.13: Shape" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2b: Function from indirect experimental evidences (e.g. phenotypes); PubMedId: 14973018, 15743965, 16514141, 26025016; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="minor cardiolipin synthetase" /protein_id="NP_391605.1" /db_xref="EnsemblGenomes-Gn:BSU37240" /db_xref="EnsemblGenomes-Tr:CAB15752" /db_xref="GOA:P45860" /db_xref="InterPro:IPR001736" /db_xref="InterPro:IPR022924" /db_xref="InterPro:IPR025202" /db_xref="InterPro:IPR027379" /db_xref="InterPro:IPR030874" /db_xref="SubtiList:BG11305" /db_xref="UniProtKB/Swiss-Prot:P45860" /translation="MLKRRLEFFFLYMMLIGAYVIWFFPVSRLEFYGGLLCYISIILF SIYSLILENRTSQHTLLWIHILVFFPIVGYVFYLFSGQLYVKGKLFKTKRMYNREKLR KLFDKEETPEVTGLKDNQERFFTYSIRAAHMNINTKSNIKVLKNGEETFPDIFKAMRK AESYIHIEYYMFKSDMLGRGMMDIMMEKARQGVEVRFLYDAAGSMKLARRDIMRMKQA GVDIVPFSPLKYGFFNQKLNFRNHRKIVIIDGKTGFVGGLNVGKEYISRDPYIGFWRD THLRLEGEIVQTLHAIFMLDWEYVSNEVLIDQEEYNTPVPVEGGGIYQIVATGPDMKE SMSDLYYEMISSAQKSIWIATPYFVPNESIRTALKAAATKGVEVRVMVPEKNDSFLTQ YASRSYFPELLLEGIEVYSYQKGFMHQKVMIIDGDLASVGTANMDMRSFQLNFEVNVF FTDAEAIRTLEAHFEEDMQESEKLSPVGFYKRGVADRTKESFARLFSGVL*" gene complement(3687168..3688670) /gene="clsC" /locus_tag="BSU_37240" /old_locus_tag="BSU37240" promotor_-10 complement(3688694..3688712) /Source="Nicolas_upshift_promotors" /id="U2934" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=216 /SigmaFactorBS="aacctctcctcctttggcggagaggttttttacttacaaGGT TTATcgattagaaaaaagAGGTAATACAGAGGTAATTgaatcagattggagagaatca g" /listShort="ywiE, ywjA, ywjB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3688712) /Source="Nicolas_upshifts" /id="U2934" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=216 /SigmaFactorBS="aacctctcctcctttggcggagaggttttttacttacaaGGT TTATcgattagaaaaaagAGGTAATACAGAGGTAATTgaatcagattggagagaatca g" /listShort="ywiE, ywjA, ywjB" /GFF_Attribute="listLong" promotor_-35 complement(3688727..3688733) /Source="Nicolas_upshift_promotors" /id="U2934" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=216 /SigmaFactorBS="aacctctcctcctttggcggagaggttttttacttacaaGGT TTATcgattagaaaaaagAGGTAATACAGAGGTAATTgaatcagattggagagaatca g" /listShort="ywiE, ywjA, ywjB" /GFF_Attribute="listLong" /label="promotor_-35" S_feature complement(3688757..3689129) /Source="Nicolas_S_feature" /locus_tag="new_3823159_3823531_c" /HighExp="Lbtran, M40t45, nit, LBGtran, LBGstat, S0, ferm, M0t45, Lbstat, BI" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.30294500000000002" /TUshortSig="SigA" /TUshortPSig="0.993" /TUlongSig="SigA" /TUlongPSig="0.996" /label="S1447" downshifts complement(3688800) /Source="Nicolas_upshifts" /id="D1926" /incds=0 /nref=4 /ntot=19 /MaxReadThrough="2.94229" /MaxDrop="4.09744" /score="13.5274489" /energy="-11.4" /TU="NA" /idTUdmin="U2935" /TUdmin=0 /isTUend="TRUE" CDS complement(3689156..3689827) /gene="narI" /locus_tag="BSU_37250" /old_locus_tag="BSU37250" /EC_number="1.7.99.4" /function="16.10: Respire" /experiment="publication(s) with functional evidences, PMID:7557333, 7860592, 8846791, 11289299, 15849754, 16850406, 22103536" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7557333, 7860592, 8846791, 11289299, 15849754, 16850406, 22103536; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="nitrate reductase (gamma subunit)" /protein_id="NP_391606.1" /db_xref="EnsemblGenomes-Gn:BSU37250" /db_xref="EnsemblGenomes-Tr:CAB15753" /db_xref="GOA:P42177" /db_xref="InterPro:IPR003816" /db_xref="InterPro:IPR023234" /db_xref="InterPro:IPR036197" /db_xref="SubtiList:BG11084" /db_xref="UniProtKB/Swiss-Prot:P42177" /translation="MSGQILWGIMPYIVLTIFIGGHIYRYQHDQFGWTAKSSELLEKK KLAAGSTLFHWGLLCVVGGHVMGILIPEGVYASLGISEHMYHKMAIGAGLPAGIAACT GLVILTYRRLFDKRIRKTSSPSDILTLLLLLFMMLSGVAATFLNIDSKGFDYRTTVGP WFREIVLFRPDASLMESVPLWFKFHIVIGYVVFILWPFTRLVHVFSLPLKYLTRSYVV YRKRS*" gene complement(3689156..3689827) /gene="narI" /locus_tag="BSU_37250" /old_locus_tag="BSU37250" downshifts complement(3689174) /Source="Nicolas_upshifts" /id="D1927" /incds=0 /nref=4 /ntot=13 /MaxReadThrough="6.70789" /MaxDrop="4.50566" /score="27.8375931" /energy="-11.7" /TU="U2935" /idTUdmin="U2935" /TUdmin="-374" /isTUend="FALSE" CDS complement(3689824..3690378) /gene="narJ" /locus_tag="BSU_37260" /old_locus_tag="BSU37260" /function="16.10: Respire" /experiment="publication(s) with functional evidences, PMID:7557333, 7860592, 8846791, 11289299" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7557333, 7860592, 8846791, 11289299; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="nitrate reductase molybdenum cofactor assembly chaperone NarJ" /protein_id="NP_391607.1" /db_xref="EnsemblGenomes-Gn:BSU37260" /db_xref="EnsemblGenomes-Tr:CAB15754" /db_xref="GOA:P42178" /db_xref="InterPro:IPR003765" /db_xref="InterPro:IPR020945" /db_xref="InterPro:IPR036411" /db_xref="SubtiList:BG11083" /db_xref="UniProtKB/Swiss-Prot:P42178" /translation="MNTTDRQITFSALSCLLSYPDEEWRAELPDWKALIQEIGNRQIR EKLLHFFETSASYSPEALIEHYVYTFDFGKKTNMYVTYFNSGEQRERGIELLHLKNTY EQSGFLPTEKELPDYLPLMLEFAAAAEIEAARSVFEKYLSNVRELASRLEKNDSIYAE LLHVLLAALENIGVRESVEGAVQA*" gene complement(3689824..3690378) /gene="narJ" /locus_tag="BSU_37260" /old_locus_tag="BSU37260" CDS complement(3690404..3691867) /gene="narH" /locus_tag="BSU_37270" /old_locus_tag="BSU37270" /EC_number="1.7.99.4" /function="16.10: Respire" /experiment="publication(s) with functional evidences, PMID:7557333, 7860592, 8846791, 11289299, 15849754, 16850406, 22103536" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7557333, 7860592, 8846791, 11289299, 15849754, 16850406, 22103536; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="nitrate reductase (beta subunit)" /protein_id="NP_391608.1" /db_xref="EnsemblGenomes-Gn:BSU37270" /db_xref="EnsemblGenomes-Tr:CAB15755" /db_xref="GOA:P42176" /db_xref="InterPro:IPR006547" /db_xref="InterPro:IPR017896" /db_xref="InterPro:IPR029263" /db_xref="SubtiList:BG11082" /db_xref="UniProtKB/Swiss-Prot:P42176" /translation="MKIKAQIGMVMNLDKCIGCHTCSVTCKNTWTNRSGAEYMYFNNV ETKPGIGYPKQWEDQDKYKGGWTLKKGKLELKSGSKTNRLAGLFYNPNQPSIDDYYEP WNYDYETLTNSPQKKHQPVARPKSSLTGDFMNIEWGPNWEDDLAGGHITGLEDPNVQK MEESIKTEFDDVFMMYLPRICEHCINPACVSSCPSGAMYKREEDGIVLVDQNACRSWR YCVSSCPYKKVYFNWQTNKAEKCTLCFPRLEAGLPTICSETCVGRIRYLGVMLYDADK VEEAASVENEKDLYHSQLDVFLDPNDPEVAKLAKEQGIPAEWIEAAQQSPIYKMIIDW KIALPLHPEYRTLPMVWYIPPLSPIMNLFEGKGSRQTAEDIFPAIDQMRIPIDYLAQL LTAGDTDHIRSTLKKMSVMRQYMRAVQTNKSIDPELISSVGLTEQQIEDMYRLLAIAK YDDRFVIPSSHREEVSDLYAEQGSCGLSFSGGPGSCF*" gene complement(3690404..3691867) /gene="narH" /locus_tag="BSU_37270" /old_locus_tag="BSU37270" CDS complement(3691857..3695543) /gene="narG" /locus_tag="BSU_37280" /old_locus_tag="BSU37280" /EC_number="1.7.5.1" /EC_number="1.7.99.4" /function="16.10: Respire" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 11289299, 7557333, 7860592, 8846791; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="nitrate reductase (alpha subunit)" /protein_id="NP_391609.2" /db_xref="EnsemblGenomes-Gn:BSU37280" /db_xref="EnsemblGenomes-Tr:CAB15756" /db_xref="GOA:P42175" /db_xref="InterPro:IPR006468" /db_xref="InterPro:IPR006655" /db_xref="InterPro:IPR006656" /db_xref="InterPro:IPR006657" /db_xref="InterPro:IPR006963" /db_xref="InterPro:IPR009010" /db_xref="InterPro:IPR027467" /db_xref="InterPro:IPR028189" /db_xref="SubtiList:BG11081" /db_xref="UniProtKB/Swiss-Prot:P42175" /translation="MKKKKRSPLFRRLNYFSPIEHHSNKHSQTTREDRDWENVYRNRW QYDKVVRSTHGVNCTGSCSWNIYVKNGIVTWEGQNLNYPSTGPDMPDFEPRGCPRGAS FSWYIYSPLRVKYPYVRGVLINLWREALQTHQNPLEAWKSIVENPEKAKSYKQARGKG GFVRAEWPEVLKLISASLLYTVMKYGPDRNVGFSPIPAMSMISHASGSRFMSLIGGPM LSFYDWYADLPPASPQIWGDQTDVPESSDWYNSGYIITWGSNVPLTRTPDAHFLAEAR YKGAKVISISPDFAESSKFADDWLSIRQGTDGALAMAMGHVILQEFYVNQETERFIEY AKQYTDFPFLVTLSKENGVYTAGRFLHAKDIGRKTKHDQWKPAVWDEQTSSFAIPQGT MGSRWDGQQKWNLHMIDEETGEPIEPRLSVLGIEDEIGTVRIPYFSNDGNKVLERDLP IKKMNLNGEETYITTVFDLILANYGVNRGIGERSAVSYDDPEPFTPAWQEQMTGIKKE AVVKIAREFAQNAIDTDGRSMIIVGAGINHWFNSDTIYRAVLNLVLLVGAQGVNGGGW AHYVGQEKLRPAEGWQTIATAKDWEGVPKLQNGTSFFYFATDQWRYEDQPISDLASPI AASSRYKHHADYNVLAARLGWLPSYPTFNQNGIDLYKEAEKAGAATPEDVGAYVASQL QEKKLKFAIEDPDNEVNFPRNLFVWRANLISSSGKGHEYFLKHLLGTTNGLMNDDSDS IRPEEIKWREQAPEGKLDLLINLDFRMAGTALYSDIVLPAATWYEKHDLSSTDMHPFI HPFAPAISAPWESKSDWDIFKALSKAVSDLAEEVDMEPVKEVVATPLLHDTMQELAQP FGKINDWSKGECEAIPGKTMPNIQVVERDYKHIFHKMTALGPNVALKPSGTKGMSWSI ADEYESLKQRLGEITSDSVAKGCPNISEAKQAAEAILTLSSTSNGKVAVKAWESLENI TNLKLKDLAEEREEECFTFEQITAQPKTVITSPAFTGSEKGGRRYSPFTTNVEKLIPW RTLTGRQSYYVDHELMMEFGETMATFKPILQHRPFLSKRPDQEGKEIVLNYLTPHNKW SVHSMYFDSLPMLTLFRGGPTVWMNKDDAEDTDIKDNDWIECFNRNGVVVARAVLSHR IPKGMAFMHHAQDRHINVPGTKLTNNRGGTHNSPTRIHVKPTQMIGGYAQLSYGFNYY GPTGNQRDLNVVIRKLKEVDWLED*" gene complement(3691857..3695543) /gene="narG" /locus_tag="BSU_37280" /old_locus_tag="BSU37280" misc_feature complement(3695574..3695593) /Source="Nicolas_upshift_promotors" /id="U2935" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.971028971028971" /psig="0.993006993006993" /xcortree=1614 /SigmaFactorBS="ctttgtgtgaacattttgtgaaaaaagcagagtgtgtgacat agttcacaaggaaacacgctgtcTCTGTTTATAGTGAACTTAGcatcacctgactcgg a" /listShort="narG, narH, narJ, narI, S1447" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(3695598) /Source="Nicolas_upshifts" /id="U2935" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.971028971028971" /psig="0.993006993006993" /xcortree=1614 /SigmaFactorBS="ctttgtgtgaacattttgtgaaaaaagcagagtgtgtgacat agttcacaaggaaacacgctgtcTCTGTTTATAGTGAACTTAGcatcacctgactcgg a" /listShort="narG, narH, narJ, narI, S1447" /GFF_Attribute="listLong" S_feature complement(3695600..3695729) /Source="Nicolas_S_feature" /locus_tag="new_3830002_3830131_c" /HighExp="Lbtran, M40t45, LBGtran, ferm, M0t45, nit, S0, Lbstat, LBGstat, M0t90" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.996" /TUlongSig="NA" /TUlongPSig="NA" /label="S1448" CDS complement(3695739..3696215) /gene="arfM" /locus_tag="BSU_37290" /old_locus_tag="BSU37290" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:10809684, 11698370, 16428414, 22178965" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10809684, 11698370, 16428414, 22178965; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator" /protein_id="NP_391610.1" /db_xref="EnsemblGenomes-Gn:BSU37290" /db_xref="EnsemblGenomes-Tr:CAB15757" /db_xref="GOA:P46910" /db_xref="InterPro:IPR014710" /db_xref="InterPro:IPR018490" /db_xref="SubtiList:BG11345" /db_xref="UniProtKB/Swiss-Prot:P46910" /translation="MNQCDYLLFLKQLPMFNEVPLSIVETLLKNGTFIRGSCDQSPSF LHSQSVYIVLKGSVRFMDTRLPEGSKTVALWEKGDVFPIDEKGGLYLSPFISVNATSD ILILNIPYYIFKKMMSYHPQLQMNFLAMLQQNVFCSYQLFLRYLHTSQDENAEPGS*" gene complement(3695739..3696215) /gene="arfM" /locus_tag="BSU_37290" /old_locus_tag="BSU37290" downshifts complement(3695774) /Source="Nicolas_upshifts" /id="D1928" /incds=0 /nref=10 /ntot=39 /MaxReadThrough="5.03469" /MaxDrop="3.83412" /score="30.7487171" /energy="-10.5" /TU="U2936" /idTUdmin="U2936" /TUdmin="-154" /isTUend="FALSE" promotor_-10 complement(3696238..3696257) /Source="Nicolas_upshift_promotors" /id="U2936" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.72927072927073" /psig="0.996003996003996" /xcortree=1613 /SigmaFactorBS="aagtgacattcatcatacaggctgtgaaatacatcACTGctg tacaggctcagTCGAGCTACACTAAAGCTATccttagcacaggaggttttcctatgaa t" /listShort="arfM, S1448" /listLong="narG, narH, narJ, narI, S1447" /label="promotor_-10" upshifts complement(3696250) /Source="Nicolas_upshifts" /id="U2936" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.72927072927073" /psig="0.996003996003996" /xcortree=1613 /SigmaFactorBS="aagtgacattcatcatacaggctgtgaaatacatcACTGctg tacaggctcagTCGAGCTACACTAAAGCTATccttagcacaggaggttttcctatgaa t" /listShort="arfM, S1448" /listLong="narG, narH, narJ, narI, S1447" promotor_-35 complement(3696272..3696275) /Source="Nicolas_upshift_promotors" /id="U2936" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.72927072927073" /psig="0.996003996003996" /xcortree=1613 /SigmaFactorBS="aagtgacattcatcatacaggctgtgaaatacatcACTGctg tacaggctcagTCGAGCTACACTAAAGCTATccttagcacaggaggttttcctatgaa t" /listShort="arfM, S1448" /listLong="narG, narH, narJ, narI, S1447" /label="promotor_-35" upshifts 3696322 /Source="Nicolas_upshifts" /id="U2937" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.988011988011988" /psig=1 /xcortree=1612 /SigmaFactorBS="gcctgtacagcagtgatgtatttcacagcctgtatgatgaat gtcacttatcaggagggtgaaTGCATTTATAATGAAAGAAAaaaggaggatttcgatg a" /listShort="ywiC" /GFF_Attribute="listLong" misc_feature 3696325..3696344 /Source="Nicolas_upshift_promotors" /id="U2937" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.988011988011988" /psig=1 /xcortree=1612 /SigmaFactorBS="gcctgtacagcagtgatgtatttcacagcctgtatgatgaat gtcacttatcaggagggtgaaTGCATTTATAATGAAAGAAAaaaggaggatttcgatg a" /listShort="ywiC" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" CDS 3696359..3697078 /gene="ywiC" /locus_tag="BSU_37300" /old_locus_tag="BSU37300" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16428414, 16850406; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative integral inner membrane protein" /protein_id="NP_391611.1" /db_xref="EnsemblGenomes-Gn:BSU37300" /db_xref="EnsemblGenomes-Tr:CAB15758" /db_xref="GOA:P46909" /db_xref="InterPro:IPR025576" /db_xref="SubtiList:BG11344" /db_xref="UniProtKB/Swiss-Prot:P46909" /translation="MKALIPKQHGAWAMLLIPFLLGMVKGGPVIWHIPLFLGWLFLYL AVYPVTLALKKKQSKPYQKWMCYYGFPTCCFLMISVFHKPPLIWVGVSLLPLFLIHMY FARRKNERALLNDVAGVLFFCSGGFASCWLGMGTLDGWAWFIFLQSALFFIGSSFYVK SVIRERKNRAFAYWSWGYHLLLPFLSALFGAGWAFLAFIPSSLRAWFFHGRDWPVKTI GILEIVNACFFLAVMCLFITR*" gene 3696359..3697078 /gene="ywiC" /locus_tag="BSU_37300" /old_locus_tag="BSU37300" downshifts 3697062 /Source="Nicolas_upshifts" /id="D1929" /incds=0 /nref=14 /ntot=34 /MaxReadThrough="2.00369" /MaxDrop="5.63285" /score="-3.54009378" /energy="-5.8" /TU="NA" /idTUdmin="U2937" /TUdmin=0 /isTUend="TRUE" CDS complement(3697110..3697826) /gene="fnr" /locus_tag="BSU_37310" /old_locus_tag="BSU37310" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:8682783, 8846791, 16796679, 21068385, 23046954" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8682783, 8846791, 16796679, 21068385, 23046954; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator of anaerobic metabolism (FNR/CAP family)" /protein_id="NP_391612.1" /db_xref="EnsemblGenomes-Gn:BSU37310" /db_xref="EnsemblGenomes-Tr:CAB15759" /db_xref="GOA:P46908" /db_xref="InterPro:IPR000595" /db_xref="InterPro:IPR012318" /db_xref="InterPro:IPR014710" /db_xref="InterPro:IPR018335" /db_xref="InterPro:IPR018490" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG11343" /db_xref="UniProtKB/Swiss-Prot:P46908" /translation="MNFLSVRPSDSDLISSDLYELLESISTKRKMEKHTYLFREGMDA EELYLIQSGLIEIGKLTSDGKDLTLRICQKHDIVGELTLFTEEPRYMLSAKVLEDGEV LVINKNKLEKELIQNGALTFEFMKWMSTHLRKIQSKIRDLLLHGKKGALYSTLIRLSN SYGVERSDGILINIVLTNQDLAKFCAAARESVNRMLGDLRKKGVISIDESGKIILHKR DYLRCEIECENCPLEICNID*" gene complement(3697110..3697826) /gene="fnr" /locus_tag="BSU_37310" /old_locus_tag="BSU37310" downshifts complement(3697112) /Source="Nicolas_upshifts" /id="D1930" /incds=0 /nref=116 /ntot=238 /MaxReadThrough="3.06242" /MaxDrop="8.21489" /score="-2.80152808" /energy="-5.8" /TU="U2938,U2939" /idTUdmin="U2939" /TUdmin="-84" /isTUend="FALSE" downshifts complement(3697182) /Source="Nicolas_upshifts" /id="D1931" /incds=1 /nref=1 /ntot=1 /MaxReadThrough="8.51297" /MaxDrop="3.71248" /score="-2.80152808" /energy="-5.8" /TU="U2938,U2939" /idTUdmin="U2939" /TUdmin="-154" /isTUend="FALSE" misc_feature complement(3697852..3697871) /Source="Nicolas_upshift_promotors" /id="U2938" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.556443556443556" /psig="0.999000999001" /xcortree=1623 /SigmaFactorBS="cactggggcattcacaagattgttagttttttctcgatgggt acaaatcaattCACGTTACAATAAACACACAacgtgactttcttcgaggtgagctcat g" /listShort="fnr" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(3697864) /Source="Nicolas_upshifts" /id="U2938" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.556443556443556" /psig="0.999000999001" /xcortree=1623 /SigmaFactorBS="cactggggcattcacaagattgttagttttttctcgatgggt acaaatcaattCACGTTACAATAAACACACAacgtgactttcttcgaggtgagctcat g" /listShort="fnr" /GFF_Attribute="listLong" CDS complement(3697925..3699112) /gene="narK" /locus_tag="BSU_37320" /old_locus_tag="BSU37320" /function="16.8: Protect" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:8682783, 8846791, 15849754, 16796679, 16850406, 26786044" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8682783, 8846791, 15849754, 16796679, 16850406, 26786044; Product type t : transporter" /codon_start=1 /transl_table=11 /product="nitrite extrusion permease" /protein_id="NP_391613.2" /db_xref="EnsemblGenomes-Gn:BSU37320" /db_xref="EnsemblGenomes-Tr:CAB15760" /db_xref="GOA:P46907" /db_xref="InterPro:IPR011701" /db_xref="InterPro:IPR020846" /db_xref="InterPro:IPR036259" /db_xref="SubtiList:BG11342" /db_xref="UniProtKB/Swiss-Prot:P46907" /translation="MINRQHIQLSLQSLSLVAGFMVWVLISSLISQITLDIHLSKGEI SLVTAIPVILGSLLRIPLGYLTNRFGARLMFMVSFILLLFPVFWISIADSLFDLIAGG FFLGIGGAVFSIGVTSLPKYYPKEKHGVVNGIYGAGNIGTAVTTFAAPVIAQAVGWKS TVQMYLILLAVFALLHVLFGDRHEKKVKVSVKTQIKAVYRNHVLWFLSLFYFITFGAF VAFTIYLPNFLVEHFGLNPADAGLRTAGFIAVSTLLRPAGGFLADKMSPLRILMFVFA GLTLSGIILSFSPTIGLYTFGSLTVAVCSGIGNGTVFKLVPFYFSKQAGIANGIVSAM GGLGGFFPPLILASVFQATGQYAIGFMALSEVALASFVLVIWMYWQERMKTHTERNSQ SIN*" gene complement(3697925..3699112) /gene="narK" /locus_tag="BSU_37320" /old_locus_tag="BSU37320" misc_feature complement(3699142..3699161) /Source="Nicolas_upshift_promotors" /id="U2939" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.982017982017982" /psig="0.998001998001998" /xcortree=1615 /SigmaFactorBS="gctttgtcctttttttatgagaaaaacgtgtgatgtaattca caatcctgtttggctagTTTTTGTATGATAAGACTGAttattgaatcattgaaagggg c" /listShort="narK, fnr" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(3699160) /Source="Nicolas_upshifts" /id="U2939" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.982017982017982" /psig="0.998001998001998" /xcortree=1615 /SigmaFactorBS="gctttgtcctttttttatgagaaaaacgtgtgatgtaattca caatcctgtttggctagTTTTTGTATGATAAGACTGAttattgaatcattgaaagggg c" /listShort="narK, fnr" /GFF_Attribute="listLong" CDS complement(3699248..3700918) /gene="argS" /locus_tag="BSU_37330" /old_locus_tag="BSU37330" /EC_number="6.1.1.19" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:8289305, 9862121" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8289305, 9862121; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="arginyl-tRNA synthetase" /protein_id="NP_391614.1" /db_xref="EnsemblGenomes-Gn:BSU37330" /db_xref="EnsemblGenomes-Tr:CAB15761" /db_xref="GOA:P46906" /db_xref="InterPro:IPR001278" /db_xref="InterPro:IPR001412" /db_xref="InterPro:IPR005148" /db_xref="InterPro:IPR008909" /db_xref="InterPro:IPR009080" /db_xref="InterPro:IPR014729" /db_xref="InterPro:IPR035684" /db_xref="InterPro:IPR036695" /db_xref="SubtiList:BG11341" /db_xref="UniProtKB/Swiss-Prot:P46906" /translation="MNIAEQMKDVLKEEIKAAVLKAGLAEESQIPNVVLETPKDKTHG DYSTNMAMQLARVAKKAPRQIAEEIVAHFDKGKASIEKLDIAGPGFINFYMNNQYLTK LIPSVLEAGEAYGETNIGNGERVQVEFVSANPTGDLHLGHARGAAVGDSLCNVLSKAG YDVSREYYINDAGNQINNLALSVEVRYFEALGLEKPMPEDGYRGEDIIAIGKRLAEEY GDRFVNEEESERLAFFREYGLKYELEKLRKDLENFRVPFDVWYSETSLYQNGKIDKAL EALREKGHVYEEDGATWFRSTTFGDDKDRVLIKKDGTYTYLLPDIAYHKDKLDRGFDK LINVWGADHHGYIPRMKAAIEALGYEKGTLEVEIIQLVHLYKNGEKMKMSKRTGKAVT MRDLIEEVGLDAVRYFFAMRSADTHMDFDLDLAVSTSNENPVYYAQYAHARICSMLRQ GEEQGLKPAADLDFSHIQSEKEYDLLKTIGGFPEAVAEAAEKRIPHRVTNYIYDLASA LHSFYNAEKVIDPENEEKSRARLALMKATQITLNNALQLIGVSAPEKM*" gene complement(3699248..3700918) /gene="argS" /locus_tag="BSU_37330" /old_locus_tag="BSU37330" downshifts complement(3699250) /Source="Nicolas_upshifts" /id="D1932" /incds=0 /nref=252 /ntot=266 /MaxReadThrough="1.71727" /MaxDrop="6.56513" /score="23.3947976" /energy="-12.5" /TU="NA" /idTUdmin="U2941" /TUdmin=0 /isTUend="TRUE" CDS complement(3700915..3701343) /gene="ywiB" /locus_tag="BSU_37340" /old_locus_tag="BSU37340" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 22333191; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="putative RNA binding protein" /protein_id="NP_391615.1" /db_xref="EnsemblGenomes-Gn:BSU37340" /db_xref="EnsemblGenomes-Tr:CAB15762" /db_xref="InterPro:IPR012674" /db_xref="InterPro:IPR015231" /db_xref="PDB:1R0U" /db_xref="SubtiList:BG14161" /db_xref="UniProtKB/Swiss-Prot:O07624" /translation="MKQETPITLHVKSVIEDDGNQEVIEFRTTGFYYVKQNKVYLSYY EEHDLGKVKTIVKVSEGEVLVMRSGAVKMNQRFVTGASTIAKYKMSFGELELKTSTKS IQSDLDEEKGRISIAYDMHVGDEQEHLHNMTITYEGGTHA*" gene complement(3700915..3701343) /gene="ywiB" /locus_tag="BSU_37340" /old_locus_tag="BSU37340" misc_feature 3701411..3701425 /Source="Nicolas_upshift_promotors" /id="U2940" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.911088911088911" /psig="0.056943056943057" /xcortree=297 /SigmaFactorBS="ttcatcattccactttgacttgaatagtataatcattcggtt tgtaaacttcaACTGCTTCTATCTTAccatcattgctcatcagatttgaagataaacc t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" promotor_-10 complement(3701411..3701430) /Source="Nicolas_upshift_promotors" /id="U2941" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.53946053946054" /psig=1 /xcortree=2566 /SigmaFactorBS="ctcttctatataaggaaatgctttttatgaggtttatCTTCa aatctgatgagcaatGATGGTAAGATAGAAGCAGTtgaagtttacaaaccgaatgatt a" /listShort="ywiB, argS" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3701418 /Source="Nicolas_upshifts" /id="U2940" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.911088911088911" /psig="0.056943056943057" /xcortree=297 /SigmaFactorBS="ttcatcattccactttgacttgaatagtataatcattcggtt tgtaaacttcaACTGCTTCTATCTTAccatcattgctcatcagatttgaagataaacc t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" upshifts complement(3701427) /Source="Nicolas_upshifts" /id="U2941" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.53946053946054" /psig=1 /xcortree=2566 /SigmaFactorBS="ctcttctatataaggaaatgctttttatgaggtttatCTTCa aatctgatgagcaatGATGGTAAGATAGAAGCAGTtgaagtttacaaaccgaatgatt a" /listShort="ywiB, argS" /GFF_Attribute="listLong" promotor_-35 complement(3701447..3701450) /Source="Nicolas_upshift_promotors" /id="U2941" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.53946053946054" /psig=1 /xcortree=2566 /SigmaFactorBS="ctcttctatataaggaaatgctttttatgaggtttatCTTCa aatctgatgagcaatGATGGTAAGATAGAAGCAGTtgaagtttacaaaccgaatgatt a" /listShort="ywiB, argS" /GFF_Attribute="listLong" /label="promotor_-35" misc_feature complement(3701482..3701501) /Source="Nicolas_upshift_promotors" /id="U2942" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.802197802197802" /psig="0.932067932067932" /xcortree=1621 /SigmaFactorBS="gtgaaaaggaaatgatagatttcggaaaaatgtaacatttcc taaaggtaattAGTGATATGATTTTCTCTTCtatataaggaaatgctttttatgaggt t" /GFF_Attribute="listShort" /listLong="ywiB, argS" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(3701494) /Source="Nicolas_upshifts" /id="U2942" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.802197802197802" /psig="0.932067932067932" /xcortree=1621 /SigmaFactorBS="gtgaaaaggaaatgatagatttcggaaaaatgtaacatttcc taaaggtaattAGTGATATGATTTTCTCTTCtatataaggaaatgctttttatgaggt t" /GFF_Attribute="listShort" /listLong="ywiB, argS" promotor_-35 3701574..3701581 /Source="Nicolas_upshift_promotors" /id="U2943" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.583416583416583" /psig=1 /xcortree=1610 /SigmaFactorBS="tccgaaatctatcatttccttttcacatttttttcaaaatat atgTATTGAATtagtaatttgatAGTTTTAAGATAAAAGTACAacatagatctgctag a" /listShort="sboA, sboX, albA, albB, albC, albD, albE, albF, albG, S1450" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 3701589 /Source="Nicolas_upshifts" /id="U2943" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.583416583416583" /psig=1 /xcortree=1610 /SigmaFactorBS="tccgaaatctatcatttccttttcacatttttttcaaaatat atgTATTGAATtagtaatttgatAGTTTTAAGATAAAAGTACAacatagatctgctag a" /listShort="sboA, sboX, albA, albB, albC, albD, albE, albF, albG, S1450" /GFF_Attribute="listLong" promotor_-10 3701594..3701613 /Source="Nicolas_upshift_promotors" /id="U2943" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.583416583416583" /psig=1 /xcortree=1610 /SigmaFactorBS="tccgaaatctatcatttccttttcacatttttttcaaaatat atgTATTGAATtagtaatttgatAGTTTTAAGATAAAAGTACAacatagatctgctag a" /listShort="sboA, sboX, albA, albB, albC, albD, albE, albF, albG, S1450" /GFF_Attribute="listLong" /label="promotor_-10" downshifts 3701638 /Source="Nicolas_upshifts" /id="D1933" /incds=0 /nref=1 /ntot=3 /MaxReadThrough="8.77621" /MaxDrop="1.77243" /score="6.03938699" /energy="-13.2" /TU="U2943" /idTUdmin="U2937" /TUdmin=4576 /isTUend="FALSE" CDS 3701656..3701787 /gene="sboA" /locus_tag="BSU_37350" /old_locus_tag="BSU37350" /function="16.8: Protect" /function="16.4: Excrete" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:12696888, 15743949, 16095584, 17213266, 27914001" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12696888, 15743949, 16095584, 17213266, 27914001; Product type f: factor" /codon_start=1 /transl_table=11 /product="subtilosin A" /protein_id="NP_391616.1" /db_xref="EnsemblGenomes-Gn:BSU37350" /db_xref="EnsemblGenomes-Tr:CAB15763" /db_xref="GOA:O07623" /db_xref="InterPro:IPR021539" /db_xref="PDB:1PXQ" /db_xref="SubtiList:BG12671" /db_xref="UniProtKB/Swiss-Prot:O07623" /translation="MKKAVIVENKGCATCSIGAACLVDGPIPDFEIAGATGLFGLWG* " gene 3701656..3701787 /gene="sboA" /locus_tag="BSU_37350" /old_locus_tag="BSU37350" CDS 3701744..3701896 /gene="sboX" /locus_tag="BSU_37360" /old_locus_tag="BSU37360" /function="16.5: Explore" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15743949; Product type f: factor" /codon_start=1 /transl_table=11 /product="putative bacteriocin-like product" /protein_id="YP_054594.1" /db_xref="EnsemblGenomes-Gn:BSU37360" /db_xref="EnsemblGenomes-Tr:CAE01468" /db_xref="SubtiList:BG14182" /db_xref="UniProtKB/Swiss-Prot:Q7WY57" /translation="MKLPVQQVYSVYGGKDLPKGHSHSTMPFLSKLQFLTKIYLLDIH TQPFFI*" gene 3701744..3701896 /gene="sboX" /locus_tag="BSU_37360" /old_locus_tag="BSU37360" downshifts 3701776 /Source="Nicolas_upshifts" /id="D1934" /incds=0 /nref=4 /ntot=32 /MaxReadThrough="8.85351" /MaxDrop="5.1396" /score="6.03938699" /energy="-13.2" /TU="U2943" /idTUdmin="U2937" /TUdmin=4714 /isTUend="FALSE" promotor_-35 3701891..3701897 /Source="Nicolas_upshift_promotors" /id="U2944" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.482517482517482" /psig="0.99000999000999" /xcortree=3233 /SigmaFactorBS="atctacctcttggatatacatacacaaccgtttttcATTTGA AtcatatgtatagggGATGGTATTTTGTTTATAGAgcagatgtttccatttattaatg a" /listShort="albA, albB, albC, albD, albE, albF, albG, S1450" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3701912..3701931 /Source="Nicolas_upshift_promotors" /id="U2944" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.482517482517482" /psig="0.99000999000999" /xcortree=3233 /SigmaFactorBS="atctacctcttggatatacatacacaaccgtttttcATTTGA AtcatatgtatagggGATGGTATTTTGTTTATAGAgcagatgtttccatttattaatg a" /listShort="albA, albB, albC, albD, albE, albF, albG, S1450" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3701915 /Source="Nicolas_upshifts" /id="U2944" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.482517482517482" /psig="0.99000999000999" /xcortree=3233 /SigmaFactorBS="atctacctcttggatatacatacacaaccgtttttcATTTGA AtcatatgtatagggGATGGTATTTTGTTTATAGAgcagatgtttccatttattaatg a" /listShort="albA, albB, albC, albD, albE, albF, albG, S1450" /GFF_Attribute="listLong" CDS 3701921..3703267 /gene="albA" /locus_tag="BSU_37370" /old_locus_tag="BSU37370" /EC_number="1.21.98.-" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:15066831, 15743949, 22366720" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15066831, 15743949, 22366720; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="subtilosin A thioether formation enzyme" /protein_id="NP_391617.1" /db_xref="EnsemblGenomes-Gn:BSU37370" /db_xref="EnsemblGenomes-Tr:CAB15764" /db_xref="GOA:P71011" /db_xref="InterPro:IPR006638" /db_xref="InterPro:IPR007197" /db_xref="InterPro:IPR008792" /db_xref="InterPro:IPR013785" /db_xref="InterPro:IPR017200" /db_xref="InterPro:IPR023885" /db_xref="InterPro:IPR034395" /db_xref="InterPro:IPR034481" /db_xref="SubtiList:BG12471" /db_xref="UniProtKB/Swiss-Prot:P71011" /translation="MFIEQMFPFINESVRVHQLPEGGVLEIDYLRDNVSISDFEYLDL NKTAYELCMRMDGQKTAEQILAEQCAVYDESPEDHKDWYYDMLNMLQNKQVIQLGNRA SRHTITTSGSNEFPMPLHATFELTHRCNLKCAHCYLESSPEALGTVSIEQFKKTADML FDNGVLTCEITGGEIFVHPNANEILDYVCKKFKKVAVLTNGTLMRKESLELLKTYKQK IIVGISLDSVNSEVHDSFRGRKGSFAQTCKTIKLLSDHGIFVRVAMSVFEKNMWEIHD MAQKVRDLGAKAFSYNWVDDFGRGRDIVHPTKDAEQHRKFMEYEQHVIDEFKDLIPII PYERKRAANCGAGWKSIVISPFGEVRPCALFPKEFSLGNIFHDSYESIFNSPLVHKLW QAQAPRFSEHCMKDKCPFSGYCGGCYLKGLNSNKYHRKNICSWAKNEQLEDVVQLI*" gene 3701921..3703267 /gene="albA" /locus_tag="BSU_37370" /old_locus_tag="BSU37370" CDS 3703280..3703441 /gene="albB" /locus_tag="BSU_37380" /old_locus_tag="BSU37380" /function="16.4: Excrete" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:10809709, 15743949" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10809709, 15743949; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="membrane component involved in subtilosin production" /protein_id="NP_391618.1" /db_xref="EnsemblGenomes-Gn:BSU37380" /db_xref="EnsemblGenomes-Tr:CAB15765" /db_xref="GOA:P71010" /db_xref="SubtiList:BG12470" /db_xref="UniProtKB/Swiss-Prot:P71010" /translation="MSPAQRRILLYILSFIFVIGAVVYFVKSDYLFTLIFIAIAILFG MRARKADSR*" gene 3703280..3703441 /gene="albB" /locus_tag="BSU_37380" /old_locus_tag="BSU37380" CDS 3703438..3704157 /gene="albC" /locus_tag="BSU_37390" /old_locus_tag="BSU37390" /function="16.5: Explore" /function="16.6: Maintain" /function="16.4: Excrete" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 10809709, 15066831, 15743949; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative transporter involved in subtilosin production" /protein_id="NP_391619.1" /db_xref="EnsemblGenomes-Gn:BSU37390" /db_xref="EnsemblGenomes-Tr:CAB15766" /db_xref="GOA:P71009" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG12469" /db_xref="UniProtKB/Swiss-Prot:P71009" /translation="MSILDIHDVSVWYERDNVILEQVDLHLEKGAVYGLLGVNGAGKT TLINTLTGVNRNFSGRFTLCGIEAEAGMPQKTSDQLKTHRYFAADYPLLFTEITAKDY VSFVHSLYQKDFSEQQFASLAEAFHFSKYINRRISELSLGNRQKVVLMTGLLLRAPLF ILDEPLVGLDVESIEVFYQKMREYCEAGGTILFSSHLLDVVQRFCDYAAILHNKQIQK VIPIGEETDLRREFFEVIGHE*" gene 3703438..3704157 /gene="albC" /locus_tag="BSU_37390" /old_locus_tag="BSU37390" CDS 3704150..3705460 /gene="albD" /locus_tag="BSU_37400" /old_locus_tag="BSU37400" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2b: Function from indirect experimental evidences (e.g. phenotypes); PubMedId: 10809709, 15066831, 15743949, 15849754, 16850406, 18034824; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="integral membrane protein involved in subtilosinproduction and immunity" /protein_id="NP_391620.1" /db_xref="EnsemblGenomes-Gn:BSU37400" /db_xref="EnsemblGenomes-Tr:CAB15767" /db_xref="GOA:P71008" /db_xref="SubtiList:BG12468" /db_xref="UniProtKB/Swiss-Prot:P71008" /translation="MNNIIPIMSLLFKQLYSRQGKKDAIRIAAGLVILAVFEIGLIRQ AGIDESVLRKTYIILALLLMNTYMVFLSVTSQWKESYMKLSCLLPISSRSFWLAQSVV LFVDTCLRRTLFFFILPLFLFGNGTLSGAQTLFWLGRFSFFTVYSIIFGVVLSNHFVK KKNLMFLLHAAIFACVCISAALMPAATIPLCAVHILWAVVIDFPVFLQAPPQQGKMHS FMRRSEFSFYKREWNRFISSKAMLLNYAVMAVFSGFFSFQMMNTGIFNQQVIYIVISA LLLICSPIALLYSIEKNDRMLLITLPIKRKTMFWAKYRFYSGLLAGGFLLVVMIVGFI SGRSISVLTFLQCIELLLAGAYIRLTADEKRPSFSWQTEQQLWSGFSKYRSYLFCLPL FLAILAGTAVSLAVIPIAGLVIVYYLQKQDGGFFDTSKRERLGS*" gene 3704150..3705460 /gene="albD" /locus_tag="BSU_37400" /old_locus_tag="BSU37400" CDS 3705450..3706610 /gene="albE" /locus_tag="BSU_37410" /old_locus_tag="BSU37410" /function="16.8: Protect" /function="16.5: Explore" /function="16.4: Excrete" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2b: Function from indirect experimental evidences (e.g. phenotypes); PubMedId: 10809709, 15066831, 15743949; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="peptidase involved in subtilosin A production" /protein_id="NP_391621.1" /db_xref="EnsemblGenomes-Gn:BSU37410" /db_xref="EnsemblGenomes-Tr:CAB15768" /db_xref="GOA:P71007" /db_xref="InterPro:IPR007863" /db_xref="InterPro:IPR011249" /db_xref="SubtiList:BG12467" /db_xref="UniProtKB/Swiss-Prot:P71007" /translation="MEVNLLKTHQFSTISIAASFLKPIESAAEPEEETIYFYGAAAYL KEQIIDAFGYAAGSRFMYSANLFFDQQLKTCGTRLIHPLYNGNLHVDALMKTFADLSF PSSLSFEAFEKARNELLLKIEKKFTDPFSYSAARLAEEVFGNPMYGTGMFGRRDRIKA IHPKRFLDATDFIVDLVSQQKQLNILGQVQACDVRGHAPQTSAVTSGRIPVNRHVFET ETRSAAGPSVLTLGFDCGEMKDASDYIKIQLIDGLLGKYGHSALFKHFREKDLAVYHV ITRYDVMNNLLLVSICTDQLHEKDIPPRVLEAVSAFHTDERELEQAKQFLRNELLLQF DSPEGLLAYMGVLRRFSCTKEALLDGISAVTCRDVLQFIATINYIGAHVVRG*" gene 3705450..3706610 /gene="albE" /locus_tag="BSU_37410" /old_locus_tag="BSU37410" CDS 3706615..3707895 /gene="albF" /locus_tag="BSU_37420" /old_locus_tag="BSU37420" /EC_number="3.4.24.-" /function="16.8: Protect" /function="16.4: Excrete" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 10809709, 15066831, 15743949, 25817994; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative peptidase involved in subtilosin production" /protein_id="NP_391622.1" /db_xref="EnsemblGenomes-Gn:BSU37420" /db_xref="EnsemblGenomes-Tr:CAB15769" /db_xref="GOA:P71006" /db_xref="InterPro:IPR011249" /db_xref="InterPro:IPR011765" /db_xref="SubtiList:BG12466" /db_xref="UniProtKB/Swiss-Prot:P71006" /translation="MEKKAFFQQLDERTDIRYTDSGLKIFRLKFPRAHLRLCNVKIDF GSRDVCIRAESGDTLLPYGTAHFLEHLLFWHNGRNLYSDFFAHGALLNAFTTYTDTNF MFTSLPDRLRQTIPILLDALWNHSFDKKIVAQEKAVITSEIQTAHLNHQLSYHYQLIS MLSPSSPAAVFPAGRIEDIEALDISDLQKAYKAAYQAHRMTLFLIGGSENTETLLPPH LQLEKRPDYHAERKIIPACPPVLSQKMMLGDEERMEDTWTGLQIGALPGQNDLLSIKL YWDIAARILFQLDSPFFQEIQQTYRLEIDRLSAETYIYEDGGFLILHSQGTHSSAYID VASYYVTQKKEQVAAWLQYGKDSLTDAIIYDSDYVRKCFEWAAECDRCDCSFLDMYHI IQDMDAQVFLSLIDAMASSNKAIIHVSQKEAIRQ*" gene 3706615..3707895 /gene="albF" /locus_tag="BSU_37420" /old_locus_tag="BSU37420" CDS 3707892..3708593 /gene="albG" /locus_tag="BSU_37430" /old_locus_tag="BSU37430" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 10809709, 15066831, 15849754, 16850406; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative integral membrane protein involved in subtilosin production and immunity" /protein_id="NP_391623.1" /db_xref="EnsemblGenomes-Gn:BSU37430" /db_xref="EnsemblGenomes-Tr:CAB15770" /db_xref="GOA:P71005" /db_xref="SubtiList:BG12465" /db_xref="UniProtKB/Swiss-Prot:P71005" /translation="MKQSTVFTLLLLLIGMAAYSFGWVQAVAEAAAQYVQMINNDAVR LGLLACTAALLMLPAFLYLHYVTQSVKNMTAAFQKLTQSHQSCCDFQQHNLCSRYAED VKSLRDSYKNVRQTYVMAAVLCQVIIFGCMFEIVKAVPFRLHTPPAFSMGLAMLLILY LLFCMRTYLRQLFRHGSLFRKVFAGALAAAGIWWMLSFSISELLFLIILAAIQQIGSF IYKRFSYHSTASLDL*" gene 3707892..3708593 /gene="albG" /locus_tag="BSU_37430" /old_locus_tag="BSU37430" downshifts complement(3708160) /Source="Nicolas_upshifts" /id="D1935" /incds=1 /nref=2 /ntot=5 /MaxReadThrough="0.362109999999999" /MaxDrop="3.55474" /score="6.50386958" /energy="-12" /TU="NA" /idTUdmin="U2945" /TUdmin=0 /isTUend="TRUE" S_feature complement(3708249..3708598) /Source="Nicolas_S_feature" /locus_tag="new_3842651_3843000_c" /HighExp="BT, B36, B60, Pyr, G/S, Mal, S3, G135, M/G, Sw" /AntisenseName="albG" /AntisenseCor="2.0087959212361201E-2" /AntisenseRegPval="-0.1" /CDS_PredictionProba="NA" /TUshortSig="SigK" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1449" downshifts complement(3708292) /Source="Nicolas_upshifts" /id="D1936" /incds=1 /nref=6 /ntot=18 /MaxReadThrough="3.01883" /MaxDrop="4.2137" /score="6.50386958" /energy="-12" /TU="U2945" /idTUdmin="U2945" /TUdmin="-132" /isTUend="FALSE" S_feature 3708594..3711076 /Source="Nicolas_S_feature" /locus_tag="new_3842996_3845478" /HighExp="Lbstat, nit, ferm, BI, M0t90, S2, M40t90, BT, M0t45, GM 150" /AntisenseName="ywhL" /AntisenseCor="7.7827453562424306E-2" /AntisenseRegPval="-0.7" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="0.99, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S1450" CDS complement(3708599..3709975) /gene="ywhL" /locus_tag="BSU_37440" /old_locus_tag="BSU37440" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 12073041" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_391624.1" /db_xref="EnsemblGenomes-Gn:BSU37440" /db_xref="EnsemblGenomes-Tr:CAB15771" /db_xref="InterPro:IPR011045" /db_xref="InterPro:IPR015943" /db_xref="SubtiList:BG12464" /db_xref="UniProtKB/Swiss-Prot:P71004" /translation="MKKNDLSALQENCFCFCDEEISREAPFQVPIDFPEGFKVDTAEA SAAVTWSTDNLSCISEPCLIQTGPEPEDIGVRYAVRVQGTITLLVSVSPVRNQYGQGD GAVSVIHTEEIDQVVYYAAQSGRCPDFSQITVEDLLIVPPFYGSPLTVAGTLVLPPSP DPQSYVFTANTGDSTVSVIDADLNTVVKTIPFSDVPTNLGVTFDKAFTYVLHGNTNLV SVIDNKTLTIINTITVGGGPRKIEFDPTDEFAYVMAAGSIYVINTASQSVIDVIPIPG ALDFALDPNGQYVYTANGSSWSVDKYDVNTGQLVESIIDTFEFPSLITTPYAGNFAYV LNGELWPKGVTEISLSPLSRGGDFSRLFETLRTIVFSLDSTRAYFLEPYSEPFLINNL YVVNTARQRIIANVSLPGAFDLAVTPDKQYIYAAQPNDNAVTVYRTSDYTAVTVIPVG AGPSAIAM*" gene complement(3708599..3709975) /gene="ywhL" /locus_tag="BSU_37440" /old_locus_tag="BSU37440" CDS complement(3710014..3711369) /gene="ywhK" /locus_tag="BSU_37450" /old_locus_tag="BSU37450" /function="16.6: Maintain" /function="16.9: Replicate" /experiment="publication(s) with functional evidences, PMID:12073041" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12073041; Product type f: factor" /codon_start=1 /transl_table=11 /product="factor interacting with DNA helicase PcrA" /protein_id="NP_391625.1" /db_xref="EnsemblGenomes-Gn:BSU37450" /db_xref="EnsemblGenomes-Tr:CAB15772" /db_xref="InterPro:IPR011045" /db_xref="InterPro:IPR015943" /db_xref="SubtiList:BG12463" /db_xref="UniProtKB/Swiss-Prot:P71003" /translation="MRKNKLSFKEKAGAEQEECLCFCEGEASREAMFQAPIELPEGFV VDPAEAVANVTWNADSLSCVSDRCLIQTGPEPDEVGVQFAVRLQGTVTLLVSVSPVRN QYGQGDGAVSVIHNAEIDQVVYYSDESDDCPDISDITIENLVVVPPFYGSPLSVTGTI VLVPEPEPVYAFTANPNDQSVSVIDTNTDTVVTTIALPYNPAGIEITPDKSAVFVLHP NNNVISVIDYDTLTVTATILLDQPPRLIRFIPNHEFAYVFTGTAVYVIGIDTLTVDRS IPVEGYDVAIDPNGLFAYVLNFGIVQKVDLTTGEVTGTIERELIVSTIETNWPERYAY VLEQEFFFNYLTVIDLNTFTISSTQELEYEGEYRMFTSGAEVYLYDGFTGNLYSVSPN GAGVIGNVPQSATDYAFTPNGDFLYATRFIEQSIIVYNTDDYSEETVISLGVSPGAIT I*" gene complement(3710014..3711369) /gene="ywhK" /locus_tag="BSU_37450" /old_locus_tag="BSU37450" promotor_-10 complement(3711405..3711424) /Source="Nicolas_upshift_promotors" /id="U2945" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1430 /SigmaFactorBS="tatattttcaaaaagaagcgtttaccctcagcaatttGTACA AGCAAacacgttaccctTCCATATTCTGTTATATCTGcgtgagcagtgtatgtctgaa a" /listShort="ywhK, ywhL, S1449" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3711423) /Source="Nicolas_upshifts" /id="U2945" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1430 /SigmaFactorBS="tatattttcaaaaagaagcgtttaccctcagcaatttGTACA AGCAAacacgttaccctTCCATATTCTGTTATATCTGcgtgagcagtgtatgtctgaa a" /listShort="ywhK, ywhL, S1449" /GFF_Attribute="listLong" promotor_-35 complement(3711437..3711446) /Source="Nicolas_upshift_promotors" /id="U2945" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1430 /SigmaFactorBS="tatattttcaaaaagaagcgtttaccctcagcaatttGTACA AGCAAacacgttaccctTCCATATTCTGTTATATCTGcgtgagcagtgtatgtctgaa a" /listShort="ywhK, ywhL, S1449" /GFF_Attribute="listLong" /label="promotor_-35" misc_feature 3711549..3711568 /Source="Nicolas_upshift_promotors" /id="U2946" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.899100899100899" /psig="0.921078921078921" /xcortree=683 /SigmaFactorBS="aacatgcggtgtaacgaaagaaaaaattgcggtttttttgcg cttctcacaagaatgttGATGATAAAATATGACATATatagaattatgaagggaggga t" /listShort="rapF, phrF, S1451, ywhH" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 3711550 /Source="Nicolas_upshifts" /id="U2946" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.899100899100899" /psig="0.921078921078921" /xcortree=683 /SigmaFactorBS="aacatgcggtgtaacgaaagaaaaaattgcggtttttttgcg cttctcacaagaatgttGATGATAAAATATGACATATatagaattatgaagggaggga t" /listShort="rapF, phrF, S1451, ywhH" /GFF_Attribute="listLong" downshifts complement(3711595) /Source="Nicolas_upshifts" /id="D1937" /incds=0 /nref=7 /ntot=59 /MaxReadThrough="2.35357" /MaxDrop="4.85842" /score="29.5788849" /energy="-11.3" /TU="NA" /idTUdmin="U2948" /TUdmin=1867 /isTUend="FALSE" CDS 3711599..3712744 /gene="rapF" /locus_tag="BSU_37460" /old_locus_tag="BSU37460" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:15968044, 16816200, 23526880" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15968044, 16816200, 23526880; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="response regulator aspartate phosphatase anti-activator of ComA" /protein_id="NP_391626.1" /db_xref="EnsemblGenomes-Gn:BSU37460" /db_xref="EnsemblGenomes-Tr:CAB15773" /db_xref="GOA:P71002" /db_xref="InterPro:IPR011990" /db_xref="InterPro:IPR013026" /db_xref="InterPro:IPR019734" /db_xref="PDB:3ULQ" /db_xref="PDB:4I9C" /db_xref="PDB:4I9E" /db_xref="SubtiList:BG11968" /db_xref="UniProtKB/Swiss-Prot:P71002" /translation="MTGVISSSSIGEKINEWYMYIRRFSIPDAEYLRREIKQELDQME EDQDLHLYYSLMEFRHNLMLEYLEPLEKMRIEEQPRLSDLLLEIDKKQARLTGLLEYY FNFFRGMYELDQREYLSAIKFFKKAESKLIFVKDRIEKAEFFFKMSESYYYMKQTYFS MDYARQAYEIYKEHEAYNIRLLQCHSLFATNFLDLKQYEDAISHFQKAYSMAEAEKQP QLMGRTLYNIGLCKNSQSQYEDAIPYFKRAIAVFEESNILPSLPQAYFLITQIHYKLG KIDKAHEYHSKGMAYSQKAGDVIYLSEFEFLKSLYLSGPDEEAIQGFFDFLESKMLYA DLEDFAIDVAKYYHERKNFQKASAYFLKVEQVRQLIQGGVSLYEIEV*" gene 3711599..3712744 /gene="rapF" /locus_tag="BSU_37460" /old_locus_tag="BSU37460" promotor_-35 3712603..3712607 /Source="Nicolas_upshift_promotors" /id="U2947" /multdbtbs="SigH" /comp="M16" /sig="SigA" /pcomp="0.585414585414585" /psig="0.986013986013986" /xcortree=751 /SigmaFactorBS="gattttctcgaaagtaaaatgttgtatgctgaTCTTGaagat ttcgctattgaTGTGGCAAAATATTATCATGaacgtaaaaattttcaaaaagcttctg c" /listShort="phrF" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3712624..3712643 /Source="Nicolas_upshift_promotors" /id="U2947" /multdbtbs="SigH" /comp="M16" /sig="SigA" /pcomp="0.585414585414585" /psig="0.986013986013986" /xcortree=751 /SigmaFactorBS="gattttctcgaaagtaaaatgttgtatgctgaTCTTGaagat ttcgctattgaTGTGGCAAAATATTATCATGaacgtaaaaattttcaaaaagcttctg c" /listShort="phrF" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3712631 /Source="Nicolas_upshifts" /id="U2947" /multdbtbs="SigH" /comp="M16" /sig="SigA" /pcomp="0.585414585414585" /psig="0.986013986013986" /xcortree=751 /SigmaFactorBS="gattttctcgaaagtaaaatgttgtatgctgaTCTTGaagat ttcgctattgaTGTGGCAAAATATTATCATGaacgtaaaaattttcaaaaagcttctg c" /listShort="phrF" /GFF_Attribute="listLong" downshifts complement(3712714) /Source="Nicolas_upshifts" /id="D1938" /incds=0 /nref=1 /ntot=59 /MaxReadThrough="1.70728" /MaxDrop="2.74755" /score="29.5788849" /energy="-11.3" /TU="NA" /idTUdmin="U2948" /TUdmin=748 /isTUend="FALSE" CDS 3712728..3712847 /gene="phrF" /locus_tag="BSU_37470" /old_locus_tag="BSU37470" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:15968044, 16816200, 23526880" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15968044, 16816200, 23526880; Product type f: factor" /codon_start=1 /transl_table=11 /product="secreted regulator of the activity of phosphatase RapF" /protein_id="NP_391627.1" /db_xref="EnsemblGenomes-Gn:BSU37470" /db_xref="EnsemblGenomes-Tr:CAB15774" /db_xref="GOA:P71001" /db_xref="InterPro:IPR025899" /db_xref="SubtiList:BG11960" /db_xref="UniProtKB/Swiss-Prot:P71001" /translation="MKLKSKLLLSCLALSTVFVATTIANAPTHQIEVAQRGMI*" gene 3712728..3712847 /gene="phrF" /locus_tag="BSU_37470" /old_locus_tag="BSU37470" downshifts 3712832 /Source="Nicolas_upshifts" /id="D1939" /incds=0 /nref=240 /ntot=268 /MaxReadThrough="5.48985" /MaxDrop="6.14096" /score="19.6493244" /energy="-9.9" /TU="U2946" /idTUdmin="U2947" /TUdmin="-4" /isTUend="TRUE" S_feature 3712877..3712945 /Source="Nicolas_S_feature" /locus_tag="new_3847279_3847347" /HighExp="S2, S3, S4, S5, S6, S1, BT, S7, S8, Fru" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.921" /TUlongSig="NA" /TUlongPSig="NA" /label="S1451" CDS 3712946..3713419 /gene="ywhH" /locus_tag="BSU_37480" /old_locus_tag="BSU37480" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative tRNA editing enzyme" /protein_id="NP_391628.1" /db_xref="EnsemblGenomes-Gn:BSU37480" /db_xref="EnsemblGenomes-Tr:CAB15775" /db_xref="GOA:P71000" /db_xref="InterPro:IPR007214" /db_xref="InterPro:IPR036754" /db_xref="SubtiList:BG12462" /db_xref="UniProtKB/Swiss-Prot:P71000" /translation="MSLKSVRTHFTQWNRENDVTEFETSSATVEQAAETIGVSLSRIA KSLSFRGEGDQVILIVAAGDAKIDNKKSRQTFGFKARMLSPNEVLEQTGHEIGGVCPF GLAHDPEVYLDVSLKRFQTVFPACGSRNSAIELTPKELSEFSFSKVWIDVCKDWE*" gene 3712946..3713419 /gene="ywhH" /locus_tag="BSU_37480" /old_locus_tag="BSU37480" downshifts 3713408 /Source="Nicolas_upshifts" /id="D1940" /incds=0 /nref=30 /ntot=156 /MaxReadThrough="2.85314" /MaxDrop="4.40065" /score="-6.80415499" /energy="-11.3" /TU="NA" /idTUdmin="U2946" /TUdmin=0 /isTUend="TRUE" CDS complement(3713451..3714323) /gene="speB" /locus_tag="BSU_37490" /old_locus_tag="BSU37490" /EC_number="3.5.3.11" /function="16.2: Construct biomass (Anabolism)" /function="16.8: Protect" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:9723923, 10931887, 24678831, 28807600, 28291380" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9723923, 10931887, 24678831, 28807600, 28291380; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="agmatinase" /protein_id="NP_391629.1" /db_xref="EnsemblGenomes-Gn:BSU37490" /db_xref="EnsemblGenomes-Tr:CAB15776" /db_xref="GOA:P70999" /db_xref="InterPro:IPR005925" /db_xref="InterPro:IPR006035" /db_xref="InterPro:IPR020855" /db_xref="InterPro:IPR023696" /db_xref="SubtiList:BG12461" /db_xref="UniProtKB/Swiss-Prot:P70999" /translation="MRFDEAYSGKVFIASRPEWEEADAILYGMPMDWTVSYRPGSRFG PSRIREVSIGLEEYSPYLDRDLADLNFFDAGDIPLPFGNPQRSLDMIEEYVDSILEKG KFPMGMGGEHLVSWPVIKAMYKKYPDLAIIHFDAHTDLRVDYEGEPLSHSTPIRKAAE LIGPHNVYSFGIRSGMKEEFEWAKENGMHISKFEVLEPLKEVLPKLAGRPVYVTIDID VLDPAHAPGTGTVDAGGITSKELLASVHEIARSEVNVKGADLVEVAPVYDHSEQTANT ASKIIREMLLGFVK*" gene complement(3713451..3714323) /gene="speB" /locus_tag="BSU_37490" /old_locus_tag="BSU37490" downshifts complement(3713462) /Source="Nicolas_upshifts" /id="D1941" /incds=0 /nref=49 /ntot=171 /MaxReadThrough="2.5482" /MaxDrop="5.46925" /score="29.5788849" /energy="-11.3" /TU="NA" /idTUdmin="U2948" /TUdmin=0 /isTUend="TRUE" downshifts complement(3713528) /Source="Nicolas_upshifts" /id="D1942" /incds=1 /nref=8 /ntot=50 /MaxReadThrough="5.83631" /MaxDrop="3.87062" /score="29.5788849" /energy="-11.3" /TU="U2948" /idTUdmin="U2948" /TUdmin="-66" /isTUend="FALSE" CDS complement(3714384..3715214) /gene="speE" /locus_tag="BSU_37500" /old_locus_tag="BSU37500" /EC_number="2.5.1.16" /function="16.3: Control" /function="16.8: Protect" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:9723923, 26735940, 28546427, 28807600" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9723923, 26735940, 28546427, 28807600; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="spermidine synthase; polyamine metabolism" /protein_id="NP_391630.1" /db_xref="EnsemblGenomes-Gn:BSU37500" /db_xref="EnsemblGenomes-Tr:CAB15777" /db_xref="GOA:P70998" /db_xref="InterPro:IPR001045" /db_xref="InterPro:IPR029063" /db_xref="InterPro:IPR030373" /db_xref="InterPro:IPR030374" /db_xref="InterPro:IPR035246" /db_xref="InterPro:IPR037163" /db_xref="PDB:1IY9" /db_xref="SubtiList:BG12460" /db_xref="UniProtKB/Swiss-Prot:P70998" /translation="MSELWYTEKQTKNFGITMKVNKTLHTEQTEFQHLEMVETEEFGN MLFLDGMVMTSEKDEFVYHEMVAHVPLFTHPNPEHVLVVGGGDGGVIREILKHPSVKK ATLVDIDGKVIEYSKKFLPSIAGKLDDPRVDVQVDDGFMHIAKSENQYDVIMVDSTEP VGPAVNLFTKGFYAGIAKALKEDGIFVAQTDNPWFTPELITNVQRDVKEIFPITKLYT ANIPTYPSGLWTFTIGSKKYDPLAVEDSRFFDIETKYYTKDIHKAAFVLPKFVSDLIK *" gene complement(3714384..3715214) /gene="speE" /locus_tag="BSU_37500" /old_locus_tag="BSU37500" S_feature complement(3715215..3715310) /Source="Nicolas_S_feature" /locus_tag="new_3849617_3849712_c" /HighExp="Paraq, G180, Oxctl, H2O2, LBGexp, G150, G135, C30, dia15, Heat" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.988" /TUlongSig="NA" /TUlongPSig="NA" /label="S1452" promotor_-10 complement(3715298..3715317) /Source="Nicolas_upshift_promotors" /id="U2948" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.523476523476524" /psig="0.988011988011988" /xcortree=2546 /SigmaFactorBS="gatcgtttttaaacatcgcagaacaggacgcaTCTTTACTtt ttccccgccaTCCTCTATACTTTTTCCTTAggtgaaaatgagatttcaaccgagaata a" /listShort="S1452, speE, speB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3715309) /Source="Nicolas_upshifts" /id="U2948" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.523476523476524" /psig="0.988011988011988" /xcortree=2546 /SigmaFactorBS="gatcgtttttaaacatcgcagaacaggacgcaTCTTTACTtt ttccccgccaTCCTCTATACTTTTTCCTTAggtgaaaatgagatttcaaccgagaata a" /listShort="S1452, speE, speB" /GFF_Attribute="listLong" promotor_-35 complement(3715330..3715337) /Source="Nicolas_upshift_promotors" /id="U2948" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.523476523476524" /psig="0.988011988011988" /xcortree=2546 /SigmaFactorBS="gatcgtttttaaacatcgcagaacaggacgcaTCTTTACTtt ttccccgccaTCCTCTATACTTTTTCCTTAggtgaaaatgagatttcaaccgagaata a" /listShort="S1452, speE, speB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 3715355..3715360 /Source="Nicolas_upshift_promotors" /id="U2949" /multdbtbs="SigF,SigG" /comp="M3" /sig="SigEF" /pcomp="0.758241758241758" /psig="0.758241758241758" /xcortree=1076 /SigmaFactorBS="tggcggggaaaaagtaaagatgcgtcctgttctgcgaTGTTT AaaaacgatcttttttTCTCATAATAGTAGAAACAtaaaaaaagggggaacccgttgt g" /listShort="pbpG" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3715376..3715394 /Source="Nicolas_upshift_promotors" /id="U2949" /multdbtbs="SigF,SigG" /comp="M3" /sig="SigEF" /pcomp="0.758241758241758" /psig="0.758241758241758" /xcortree=1076 /SigmaFactorBS="tggcggggaaaaagtaaagatgcgtcctgttctgcgaTGTTT AaaaacgatcttttttTCTCATAATAGTAGAAACAtaaaaaaagggggaacccgttgt g" /listShort="pbpG" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3715378 /Source="Nicolas_upshifts" /id="U2949" /multdbtbs="SigF,SigG" /comp="M3" /sig="SigEF" /pcomp="0.758241758241758" /psig="0.758241758241758" /xcortree=1076 /SigmaFactorBS="tggcggggaaaaagtaaagatgcgtcctgttctgcgaTGTTT AaaaacgatcttttttTCTCATAATAGTAGAAACAtaaaaaaagggggaacccgttgt g" /listShort="pbpG" /GFF_Attribute="listLong" CDS 3715416..3717491 /gene="pbpG" /locus_tag="BSU_37510" /old_locus_tag="BSU37510" /function="16.5: Explore" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:10767540, 11567005" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10767540, 11567005; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="sporulation specific penicillin-binding protein 2D" /protein_id="NP_391631.2" /db_xref="EnsemblGenomes-Gn:BSU37510" /db_xref="EnsemblGenomes-Tr:CAB15778" /db_xref="GOA:P70997" /db_xref="InterPro:IPR001264" /db_xref="InterPro:IPR001460" /db_xref="InterPro:IPR012338" /db_xref="InterPro:IPR023346" /db_xref="InterPro:IPR036950" /db_xref="SubtiList:BG12459" /db_xref="UniProtKB/Swiss-Prot:P70997" /translation="MDAMTNKRLRLTLKTVRAFIFLGAFAALAAAAVFMTVILIAKYQ GAPSVQVPQSTILYASDGSKLGETNYGEKRYWVPLKDMNPTIVKATVAIEDQNFYDHH GFDYKRMAGAALADLKAFAKVQGASTITQQYARNLYLEHDKTWKRKWNEAFYTIRLEQ NYSKDEILEGYLNTIYYGHGAYGIEAASRLYFGKHAKNLTDAEAALLAGIPKGPSGYS PYVNETKAKERQKTIVRMMEKQQMISQKKADELIKEPLSYQPLNKQVSKRKAPYFYDN AMRELEKKLGMTREQIETSGLNVYTTVDKRMQRIAEETITETVNAGSDIQVGFSAIDP RTGNVLALVGGRDYQKSPFDRTTQAKRQPASTIKPLLYYKAIQSGFTPVTLMKSEETE FQIDAKGETYSPSNYNGYYANKPITLLQALALSDNIYAVKTHLFLGTNKLVKTAKEFG ITAHLQALPSLALGTEPVRPIEMVNAYAMLANGGKKIEPTFISRVTDAAGHVLYENPN QHKQVLDEKAAFVTASMMTGMFDIDLNGYTSVTGRTIANRLTRTYAGKSGTTSADSWM IGFNPKLAAGVWTGYDKNSTIDSVEEKSYAKTIWADFMEDALKGEPETAFKPPKGVTG VYIDPETGYSSGPGCAAKHYTYFVKGTEPANVCYGAEPAKQTKDRLPSKEKPASEKKW WDKWLGRHH*" gene 3715416..3717491 /gene="pbpG" /locus_tag="BSU_37510" /old_locus_tag="BSU37510" downshifts complement(3717544) /Source="Nicolas_upshifts" /id="D1943" /incds=0 /nref=2 /ntot=122 /MaxReadThrough="1.43573" /MaxDrop="3.61075" /score="-7.59753556" /energy="-10.7" /TU="NA" /idTUdmin="U2951" /TUdmin="-11" /isTUend="TRUE" S_feature complement(3717668..3717783) /Source="Nicolas_S_feature" /locus_tag="new_3852070_3852185_c" /HighExp="Sw, C90, BI, dia5, dia15, Diami, LBGexp, M0t45, Lbexp, Lbtran" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="1, 0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S1453" downshifts complement(3717711) /Source="Nicolas_upshifts" /id="D1944" /incds=0 /nref=198 /ntot=248 /MaxReadThrough="3.25498" /MaxDrop="6.4287" /score="-7.59753556" /energy="-10.7" /TU="U2951,U2952" /idTUdmin="U2952" /TUdmin="-156" /isTUend="FALSE" CDS complement(3717784..3718302) /gene="ywhD" /locus_tag="BSU_37520" /old_locus_tag="BSU37520" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_391632.1" /db_xref="EnsemblGenomes-Gn:BSU37520" /db_xref="EnsemblGenomes-Tr:CAB15779" /db_xref="InterPro:IPR014852" /db_xref="SubtiList:BG12458" /db_xref="UniProtKB/Swiss-Prot:P70996" /translation="MEEKKKKSIGFNIIKSDPTDGHGGFGVGALSLDNISPVFVDVEE KEAFVDIGAMHARSTVEKGIKFLPNKEEVPNGKPYWLVWVTIDRKEEGPYYAGVTACE MTVDRSIRRGYKSLPEHVNLMDKSMKRKIIVDKMDDSSKRVLGEFLKKHDQGLWDRSS DELKTSLLPENN*" gene complement(3717784..3718302) /gene="ywhD" /locus_tag="BSU_37520" /old_locus_tag="BSU37520" CDS complement(3718316..3718975) /gene="ywhC" /locus_tag="BSU_37530" /old_locus_tag="BSU37530" /EC_number="3.4.24.-" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406, 25649915; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative metal-dependent hydrolase; integral membrane protein" /protein_id="NP_391633.1" /db_xref="EnsemblGenomes-Gn:BSU37530" /db_xref="EnsemblGenomes-Tr:CAB15780" /db_xref="GOA:P70995" /db_xref="InterPro:IPR008915" /db_xref="SubtiList:BG12457" /db_xref="UniProtKB/Swiss-Prot:P70995" /translation="MDRFLYYPLSLMPYLVITLIVSFTMHELAHAYVAYKFGDDTAKK QGRLTLNPIKHLDPFGTILILVAGFGWARPIPVNRRFFKKPRLAGVLVSIAGPVSNLI LAFIGFFLLVLMHAYGMEMLAAFSTGLDQFFSIWIQLNLVLFLFNLLPLPPLDGYRII EDLVPPGVRAKMTQAESYGFIVFLVLFVTPLGSYVLWPMLNAGRDSILKLFSAIFQPL L*" gene complement(3718316..3718975) /gene="ywhC" /locus_tag="BSU_37530" /old_locus_tag="BSU37530" promotor_-35 3718998..3719001 /Source="Nicolas_upshift_promotors" /id="U2950" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.919080919080919" /psig="0.993006993006993" /xcortree=2205 /SigmaFactorBS="tataaaaaacggtccaagtgagatatccctctttctcaaAAT GcaagaatttactttATTCAGTATACTATAAGAAGcctctttttctaaagagaggaaa c" /listShort="ywhB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(3719011..3719030) /Source="Nicolas_upshift_promotors" /id="U2951" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.549450549450549" /psig=1 /xcortree=1882 /SigmaFactorBS="tggcatgggtgctgaatcctcctttatctcgtttcctCTCTT TAGaaaaagaggcttctTATAGTATACTGAATAAAGTaaattcttgcattttgagaaa g" /listShort="ywhC, ywhD, S1453" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-10 3719016..3719035 /Source="Nicolas_upshift_promotors" /id="U2950" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.919080919080919" /psig="0.993006993006993" /xcortree=2205 /SigmaFactorBS="tataaaaaacggtccaagtgagatatccctctttctcaaAAT GcaagaatttactttATTCAGTATACTATAAGAAGcctctttttctaaagagaggaaa c" /listShort="ywhB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3719019 /Source="Nicolas_upshifts" /id="U2950" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.919080919080919" /psig="0.993006993006993" /xcortree=2205 /SigmaFactorBS="tataaaaaacggtccaagtgagatatccctctttctcaaAAT GcaagaatttactttATTCAGTATACTATAAGAAGcctctttttctaaagagaggaaa c" /listShort="ywhB" /GFF_Attribute="listLong" upshifts complement(3719029) /Source="Nicolas_upshifts" /id="U2951" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.549450549450549" /psig=1 /xcortree=1882 /SigmaFactorBS="tggcatgggtgctgaatcctcctttatctcgtttcctCTCTT TAGaaaaagaggcttctTATAGTATACTGAATAAAGTaaattcttgcattttgagaaa g" /listShort="ywhC, ywhD, S1453" /GFF_Attribute="listLong" S_feature complement(3719031..3719314) /Source="Nicolas_S_feature" /locus_tag="new_3853433_3853716_c" /HighExp="Diami, dia5, dia15, C90, Etha, Sw, H2O2, G135, M40t45, Lbtran" /AntisenseName="ywhB" /AntisenseCor="0.10541372702249199" /AntisenseRegPval="-1.1000000000000001" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S1454" promotor_-35 complement(3719045..3719052) /Source="Nicolas_upshift_promotors" /id="U2951" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.549450549450549" /psig=1 /xcortree=1882 /SigmaFactorBS="tggcatgggtgctgaatcctcctttatctcgtttcctCTCTT TAGaaaaagaggcttctTATAGTATACTGAATAAAGTaaattcttgcattttgagaaa g" /listShort="ywhC, ywhD, S1453" /GFF_Attribute="listLong" /label="promotor_-35" CDS 3719084..3719272 /gene="hmtB" /locus_tag="BSU_37540" /old_locus_tag="BSU37540" /EC_number="5.3.2.6" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:12051677, 14624569, 14730980, 15301547, 17902707" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12051677, 14624569, 14730980, 15301547, 17902707; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="2-hydroxymuconate tautomerase (promiscuous)" /protein_id="NP_391634.1" /db_xref="EnsemblGenomes-Gn:BSU37540" /db_xref="EnsemblGenomes-Tr:CAB15781" /db_xref="GOA:P70994" /db_xref="InterPro:IPR004370" /db_xref="InterPro:IPR014347" /db_xref="InterPro:IPR018191" /db_xref="PDB:2OP8" /db_xref="PDB:2OPA" /db_xref="SubtiList:BG12456" /db_xref="UniProtKB/Swiss-Prot:P70994" /translation="MPYVTVKMLEGRTDEQKRNLVEKVTEAVKETTGASEEKIVVFIE EMRKDHYAVAGKRLSDME*" gene 3719084..3719272 /gene="hmtB" /locus_tag="BSU_37540" /old_locus_tag="BSU37540" downshifts 3719261 /Source="Nicolas_upshifts" /id="D1945" /incds=0 /nref=72 /ntot=213 /MaxReadThrough="1.74275" /MaxDrop="4.93207" /score="4.21502693" /energy="-10.5" /TU="NA" /idTUdmin="U2950" /TUdmin=0 /isTUend="TRUE" CDS complement(3719315..3719734) /gene="ywhA" /locus_tag="BSU_37550" /old_locus_tag="BSU37550" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative transcriptional regulator (MarR family)" /protein_id="NP_391635.1" /db_xref="EnsemblGenomes-Gn:BSU37550" /db_xref="EnsemblGenomes-Tr:CAB15782" /db_xref="GOA:P70993" /db_xref="InterPro:IPR000835" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG12455" /db_xref="UniProtKB/Swiss-Prot:P70993" /translation="MDHDKLEANLLDHALTKYLKSTKQLDEATVPKHVNNVRGFILRI IYRHGSCTIKDILKEVTLSPSATTTALNHLEQEGFIERSRNNNDRRTVWITLSESGRG AAEQMIENRQQLIDGMFERLTAEEKKTFLAIIAKLAQ*" gene complement(3719315..3719734) /gene="ywhA" /locus_tag="BSU_37550" /old_locus_tag="BSU37550" promotor_-10 complement(3719784..3719803) /Source="Nicolas_upshift_promotors" /id="U2952" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.635364635364635" /psig="0.999000999001" /xcortree=1951 /SigmaFactorBS="aggataaaagctgtgaattcacattttgctTTTTTGACtttc cctattcggaATCAGTAAAATAATAAGTAAatcatatcgttcgtatgttatgaatgca t" /listShort="ywhA, S1454, ywhC, ywhD, S1453" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3719795) /Source="Nicolas_upshifts" /id="U2952" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.635364635364635" /psig="0.999000999001" /xcortree=1951 /SigmaFactorBS="aggataaaagctgtgaattcacattttgctTTTTTGACtttc cctattcggaATCAGTAAAATAATAAGTAAatcatatcgttcgtatgttatgaatgca t" /listShort="ywhA, S1454, ywhC, ywhD, S1453" /GFF_Attribute="listLong" promotor_-35 complement(3719818..3719825) /Source="Nicolas_upshift_promotors" /id="U2952" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.635364635364635" /psig="0.999000999001" /xcortree=1951 /SigmaFactorBS="aggataaaagctgtgaattcacattttgctTTTTTGACtttc cctattcggaATCAGTAAAATAATAAGTAAatcatatcgttcgtatgttatgaatgca t" /listShort="ywhA, S1454, ywhC, ywhD, S1453" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3719854..3721770) /gene="thrZ" /locus_tag="BSU_37560" /old_locus_tag="BSU37560" /EC_number="6.1.1.3" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:1379177, 8288542, 9353933, 15831787" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1379177, 8288542, 9353933, 15831787; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="threonyl-tRNA synthetase" /protein_id="NP_391636.2" /db_xref="EnsemblGenomes-Gn:BSU37560" /db_xref="EnsemblGenomes-Tr:CAB15783" /db_xref="GOA:P18256" /db_xref="InterPro:IPR002314" /db_xref="InterPro:IPR002320" /db_xref="InterPro:IPR004095" /db_xref="InterPro:IPR004154" /db_xref="InterPro:IPR006195" /db_xref="InterPro:IPR012675" /db_xref="InterPro:IPR012676" /db_xref="InterPro:IPR012947" /db_xref="InterPro:IPR018163" /db_xref="InterPro:IPR033728" /db_xref="InterPro:IPR036621" /db_xref="SubtiList:BG10421" /db_xref="UniProtKB/Swiss-Prot:P18256" /translation="MSKHVHIQLPDGQIQEYPKGITIKEAAGSISSSLQKKAAAGQVN GKLVDLSFKLEEDAELSIVTLDSQEGLQVLRHTTAHVLAQAVKRLYGEVSLGVGPVIL DGFYYDMKLGKSLASGDLEAIEKEMKNIINENLEIKRIEVSYEEAEELFAQKDERLKL EILKDIPRGEDITLYQQGEFVDLCRGPHLPSTGMIKAFKLTRVSGAYWRGDSKNEVLQ RVYGVAFQKKKDLDAHLHMLEEAAKRDHRKLGKQLGLFMFSEEAPGMPFYLPKGQIVR NELERFSRELQTNAGYDEVRTPFMMNQRLWEQSGHWDHYRDNMYFSEVDDTRFAMKPM NCPGHMLIFKNSLYSYRDLPIRMAEFGQVHRHEYSGALNGMLRVRTFCQDDAHIFVRE DQIESEIKEAIRLIDEVYRTFGFEYSVELSTRPEDSLGDDSLWEASERALARVLEELG LSYEINEGDGAFYGPKIDFHIKDALKRSHQCATIQLDFQMPEKFDLTYINELNEKVRP VVIHRAVFGSIDRFFGILIEHYGGAFPVWLAPIQVQIIPVSHVHLDYCRKVQAELKQA GIRAGIDERNEKLGYKIRESQVQKIPYVLVLGDHEEQENAVNVRRFGHQQNEHVPFQT FKDKLVKQVENRGM*" gene complement(3719854..3721770) /gene="thrZ" /locus_tag="BSU_37560" /old_locus_tag="BSU37560" promotor_-10 complement(3721048..3721066) /Source="Nicolas_upshift_promotors" /id="U2953" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.713286713286713" /psig="0.713286713286713" /xcortree=1064 /SigmaFactorBS="gtgtacggggttgcgtttcaaaagaaAAAAGatttggatgcg cacctGCATATGCTAGAAGAAGCGgcaaaacgagaccatcgcaagctcggcaaacagt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3721053) /Source="Nicolas_upshifts" /id="U2953" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.713286713286713" /psig="0.713286713286713" /xcortree=1064 /SigmaFactorBS="gtgtacggggttgcgtttcaaaagaaAAAAGatttggatgcg cacctGCATATGCTAGAAGAAGCGgcaaaacgagaccatcgcaagctcggcaaacagt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(3721083..3721087) /Source="Nicolas_upshift_promotors" /id="U2953" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.713286713286713" /psig="0.713286713286713" /xcortree=1064 /SigmaFactorBS="gtgtacggggttgcgtttcaaaagaaAAAAGatttggatgcg cacctGCATATGCTAGAAGAAGCGgcaaaacgagaccatcgcaagctcggcaaacagt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" downshifts complement(3721801) /Source="Nicolas_upshifts" /id="D1946" /incds=0 /nref=1 /ntot=27 /MaxReadThrough="4.2774" /MaxDrop="3.56231" /score="36.3785359" /energy="-19.5" /TU="U2955" /idTUdmin="U2953" /TUdmin="-968" /isTUend="FALSE" misc_RNA complement(3721824..3722045) /gene="tboTB" /locus_tag="BSU_misc_RNA_57" /product="T-box" /experiment="publication(s) with functional evidences, PMID:1379177, 8288542, 9098041, 9826762, 12165569, 12547201, 1317842, 15831787" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1379177, 8288542, 9098041, 9826762, 12165569, 12547201, 1317842, 15831787; Product type n: RNA" /function="16.3: Control" gene complement(3721824..3722045) /gene="tboTB" /locus_tag="BSU_misc_RNA_57" misc_RNA complement(3722077..3722298) /gene="tboTA" /locus_tag="BSU_misc_RNA_58" /product="T-box riboswitch specific of threonine tRNA ligase" /experiment="publication(s) with functional evidences, PMID:1379177, 8288542, 9098041, 9826762, 12165569, 12547201, 1317842, 15831787" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1379177, 8288542, 9098041, 9826762, 12165569, 12547201, 1317842, 15831787; Product type n: RNA" /function="16.3: Control" gene complement(3722077..3722298) /gene="tboTA" /locus_tag="BSU_misc_RNA_58" S_feature complement(3722330..3722592) /Source="Nicolas_S_feature" /locus_tag="new_3856732_3856994_c" /HighExp="S8, S7, S6, S5, BT, Sw, B36, B60, T5.0H, T4.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.61719100000000005" /TUshortSig="SigA" /TUshortPSig="0.995" /TUlongSig="NA" /TUlongPSig="NA" /label="S1455" downshifts 3722341 /Source="Nicolas_upshifts" /id="D1947" /incds=0 /nref=1 /ntot=17 /MaxReadThrough="0.92811" /MaxDrop="3.85666" /score="1.17237511" /energy="-8.3" /TU="NA" /idTUdmin="U2950" /TUdmin=3080 /isTUend="FALSE" downshifts complement(3722373) /Source="Nicolas_upshifts" /id="D1948" /incds=0 /nref=52 /ntot=200 /MaxReadThrough="6.68945" /MaxDrop="6.6969" /score="36.414771" /energy="-17.3" /TU="U2955" /idTUdmin="U2953" /TUdmin="-1540" /isTUend="FALSE" CDS complement(3722380..3722535) /locus_tag="BSU_37569" /old_locus_tag="BSU37569" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_009514011.1" /translation="MLFTVSREGRTAEIFLTQGKQLTAFEPYQGKQVSDTVMLRYSIF KPIIMCN*" gene complement(3722380..3722535) /locus_tag="BSU_37569" /old_locus_tag="BSU37569" promotor_-35 3722542..3722545 /Source="Nicolas_upshift_promotors" /id="U2954" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.717282717282717" /psig="0.094905094905095" /xcortree=712 /SigmaFactorBS="gctgtccttccctctctggaaaccgtaaaaagcatctcgtgT CCTtatcagtgCCTGTTGTTTCAATaattttttatatcttactatatattcccacaaa g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3722554..3722567 /Source="Nicolas_upshift_promotors" /id="U2954" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.717282717282717" /psig="0.094905094905095" /xcortree=712 /SigmaFactorBS="gctgtccttccctctctggaaaccgtaaaaagcatctcgtgT CCTtatcagtgCCTGTTGTTTCAATaattttttatatcttactatatattcccacaaa g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3722561 /Source="Nicolas_upshifts" /id="U2954" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.717282717282717" /psig="0.094905094905095" /xcortree=712 /SigmaFactorBS="gctgtccttccctctctggaaaccgtaaaaagcatctcgtgT CCTtatcagtgCCTGTTGTTTCAATaattttttatatcttactatatattcccacaaa g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 complement(3722569..3722588) /Source="Nicolas_upshift_promotors" /id="U2955" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.457542457542458" /psig="0.995004995004995" /xcortree=601 /SigmaFactorBS="ctgcccataacgggactgccgcgtcagaaaaaatgtaaatca ctGATTGCGctttgtgggaataTATAGTAAGATATAAAAAATtattgaaacaacaggc a" /listShort="S1455, NA, NA, thrZ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3722592) /Source="Nicolas_upshifts" /id="U2955" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.457542457542458" /psig="0.995004995004995" /xcortree=601 /SigmaFactorBS="ctgcccataacgggactgccgcgtcagaaaaaatgtaaatca ctGATTGCGctttgtgggaataTATAGTAAGATATAAAAAATtattgaaacaacaggc a" /listShort="S1455, NA, NA, thrZ" /GFF_Attribute="listLong" promotor_-35 complement(3722602..3722608) /Source="Nicolas_upshift_promotors" /id="U2955" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.457542457542458" /psig="0.995004995004995" /xcortree=601 /SigmaFactorBS="ctgcccataacgggactgccgcgtcagaaaaaatgtaaatca ctGATTGCGctttgtgggaataTATAGTAAGATATAAAAAATtattgaaacaacaggc a" /listShort="S1455, NA, NA, thrZ" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3722615..3724015) /gene="mmr" /locus_tag="BSU_37570" /old_locus_tag="BSU37570" /function="16.1: Circulate" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:11104814, 15849754, 16850406" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11104814, 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="toxic compound efflux transporter (may export homoserine)" /protein_id="NP_391637.1" /db_xref="EnsemblGenomes-Gn:BSU37570" /db_xref="EnsemblGenomes-Tr:CAB15784" /db_xref="GOA:Q00538" /db_xref="InterPro:IPR004638" /db_xref="InterPro:IPR011701" /db_xref="InterPro:IPR020846" /db_xref="InterPro:IPR036259" /db_xref="SubtiList:BG10420" /db_xref="UniProtKB/Swiss-Prot:Q00538" /translation="MKNSGSIQESTSSTGISVLIVLALGFLMATLDVTVVNVAMADMK NTLSMSLSGVTWVVDGYILTFASLLLAGGALADRFGSKTIYILGLAVFVMASCLCAAS INGQMLIAGRLIQGIGAALFMPSSLSLLAASYLDERARARMFGLWAALVSAASALGPF IGGVLVQLAGWQSIFLINVPIGAAALISAYRILSRVPGKSSRVNIIGHLLGMMALGFL SYALIQGPSAGWRSPVILVAFTAAVLAFVLFLLREISAKTPILPASLYKNGRFSAAQF IGFLLNFALFGGMFMLSLFLQEAGGASSFMAGVELLPMMAVFVIGNLLFARLANRFEA GQLMFVSMAVSCIIALLLFVLISPDFPYWQLAVLMSVMNLCTGITVPAMTTVIMQAAG QRHTNIAGAALNANRQIGALVGVAITGVIIHLSATWYAGAGFAFLMMGAAYSLAALLV WLFLAAHNGTAASEKM*" gene complement(3722615..3724015) /gene="mmr" /locus_tag="BSU_37570" /old_locus_tag="BSU37570" CDS complement(3724015..3724485) /gene="ywgB" /locus_tag="BSU_37580" /old_locus_tag="BSU37580" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 16885456; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative transcriptional regulator" /protein_id="NP_391638.1" /db_xref="EnsemblGenomes-Gn:BSU37580" /db_xref="EnsemblGenomes-Tr:CAB15785" /db_xref="GOA:P71047" /db_xref="InterPro:IPR000944" /db_xref="InterPro:IPR030489" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG12454" /db_xref="UniProtKB/Swiss-Prot:P71047" /translation="MKMKSGMEQAVSVLLLLSRLPVQASLTSEAISQRLRVSPSYLKK LMRTLVQAGLAESLPGTKGGFTLTKPLADITLYDVYQAVEGRGSMYQGKGLLQSVFEG ESHCVLETVMAEIEDKWSNLMREESLQHVMDRVGELYDLEKIDDWVIKQVKGQL*" gene complement(3724015..3724485) /gene="ywgB" /locus_tag="BSU_37580" /old_locus_tag="BSU37580" downshifts complement(3724441) /Source="Nicolas_upshifts" /id="D1949" /incds=0 /nref=11 /ntot=145 /MaxReadThrough="2.78131" /MaxDrop="4.29115" /score="17.3758052" /energy="-11.2" /TU="NA" /idTUdmin="U2956" /TUdmin=0 /isTUend="TRUE" CDS complement(3724597..3725097) /gene="ywgA" /locus_tag="BSU_37590" /old_locus_tag="BSU37590" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 16855250" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_391639.1" /db_xref="EnsemblGenomes-Gn:BSU37590" /db_xref="EnsemblGenomes-Tr:CAB15786" /db_xref="SubtiList:BG12453" /db_xref="UniProtKB/Swiss-Prot:P71046" /translation="MLKEHAKLMKVFSDSGEIIGRKKLQKMIYIAKKMQFPFYEKYDF HFYGPYSEELTLQIEELCNLGFLHEVKEKKGGYFQYRYSLTETGSAFLDHADLDMPDM KGYIDSVNSRSSRFLELVSTILYFDGLEDEEKKEKVFTIKSKQKYTNEEYDEALQYIE ELKQIC*" gene complement(3724597..3725097) /gene="ywgA" /locus_tag="BSU_37590" /old_locus_tag="BSU37590" downshifts complement(3724600) /Source="Nicolas_upshifts" /id="D1950" /incds=0 /nref=9 /ntot=105 /MaxReadThrough="4.00805" /MaxDrop="6.12059" /score="17.3758052" /energy="-11.2" /TU="U2956,U2957" /idTUdmin="U2957" /TUdmin="-137" /isTUend="FALSE" CDS complement(3725133..3726434) /gene="ywfO" /locus_tag="BSU_37600" /old_locus_tag="BSU37600" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 16855250; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative metal-dependent nucleotide (pyro)phosphohydrolase" /protein_id="NP_391640.1" /db_xref="EnsemblGenomes-Gn:BSU37600" /db_xref="EnsemblGenomes-Tr:CAB15787" /db_xref="GOA:P39651" /db_xref="InterPro:IPR003607" /db_xref="InterPro:IPR006674" /db_xref="SubtiList:BG10639" /db_xref="UniProtKB/Swiss-Prot:P39651" /translation="MAYPNGKLSEEKVFKDPVHRYVHVRDKLIWDLIGTREFQRLRRI KQLGTTYLTFHGAEHSRFNHSLGVYEIVRRMVDDVFKGRPEWDDSERELCLAAALLHD LGHGPFSHSFEKVFHLDHEDFTRGIILGDTEVNQVLRKVSPGFPQDVAEVIAKTYKNK QVVSLISSQIDADRMDYLQRDAYYTGVSYGHFDMERILRVMRPREDQIVIKESGMHAV EDYIMSRYQMYWQVYFHPVTRSAEVILTKILHRAKQLHDEGYVFTHAPVHFYSIFEGK LTLEDYVKLDESIILYYFQAWEDEEDAILSDLCRRFINRQLFQYVEFNPNEEMSAYFE LTSLFKEAGIDPSYYLVVDSSSDLPYDFYRPGEEEERLPIHLLTQNGQIKELSRQSAI VESISGKRRTDHKLYYPKDLICDGTKHPEAKMKIRQLLGLT*" gene complement(3725133..3726434) /gene="ywfO" /locus_tag="BSU_37600" /old_locus_tag="BSU37600" promotor_-10 complement(3726458..3726477) /Source="Nicolas_upshift_promotors" /id="U2956" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.57042957042957" /psig="0.992007992007992" /xcortree=2244 /SigmaFactorBS="tcatgaagatggaacaaatcgccgggcaaattcaaggATGtt ttcaaagaatagaGTCGATATAATAGAAACACGgctaaaaaaaagagggaatgacgat g" /listShort="ywfO, ywgA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3726472) /Source="Nicolas_upshifts" /id="U2956" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.57042957042957" /psig="0.992007992007992" /xcortree=2244 /SigmaFactorBS="tcatgaagatggaacaaatcgccgggcaaattcaaggATGtt ttcaaagaatagaGTCGATATAATAGAAACACGgctaaaaaaaagagggaatgacgat g" /listShort="ywfO, ywgA" /GFF_Attribute="listLong" S_feature complement(3726474..3726595) /Source="Nicolas_S_feature" /locus_tag="new_3860876_3860997_c" /HighExp="G180, Paraq, Oxctl, G135, H2O2, G150, C30, LBGstat, LBGexp, Heat" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1456" promotor_-35 complement(3726493..3726495) /Source="Nicolas_upshift_promotors" /id="U2956" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.57042957042957" /psig="0.992007992007992" /xcortree=2244 /SigmaFactorBS="tcatgaagatggaacaaatcgccgggcaaattcaaggATGtt ttcaaagaatagaGTCGATATAATAGAAACACGgctaaaaaaaagagggaatgacgat g" /listShort="ywfO, ywgA" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3726596..3726820) /gene="ywzC" /locus_tag="BSU_37610" /old_locus_tag="BSU37610" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 16855250" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_391641.1" /db_xref="EnsemblGenomes-Gn:BSU37610" /db_xref="EnsemblGenomes-Tr:CAB15788" /db_xref="InterPro:IPR009910" /db_xref="InterPro:IPR020880" /db_xref="SubtiList:BG14164" /db_xref="UniProtKB/Swiss-Prot:O32280" /translation="MANEFRVCDDCQATNIKTLLPRLKEVDPDAKVEVGCQSYCGPGR KKSFAFVNNRPLSAPTEDELIDKVKKKIKK*" gene complement(3726596..3726820) /gene="ywzC" /locus_tag="BSU_37610" /old_locus_tag="BSU37610" S_feature complement(3726821..3726905) /Source="Nicolas_S_feature" /locus_tag="new_3861223_3861307_c" /HighExp="G180, Paraq, H2O2, G135, LBGexp, dia15, G150, Lbexp, Heat, Cold" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1457" promotor_-10 complement(3726894..3726913) /Source="Nicolas_upshift_promotors" /id="U2957" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.543456543456543" /psig=1 /xcortree=2595 /SigmaFactorBS="ctgaaagaataggagatacgaaggatggagcggCTTGcagga acagtcgaaTCCTTGTAAAATGAAGTGTGatgtgattttttttgaaacgtgattttag g" /listShort="S1457, ywzC, S1456, ywfO, ywgA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3726904) /Source="Nicolas_upshifts" /id="U2957" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.543456543456543" /psig=1 /xcortree=2595 /SigmaFactorBS="ctgaaagaataggagatacgaaggatggagcggCTTGcagga acagtcgaaTCCTTGTAAAATGAAGTGTGatgtgattttttttgaaacgtgattttag g" /listShort="S1457, ywzC, S1456, ywfO, ywgA" /GFF_Attribute="listLong" promotor_-35 complement(3726928..3726931) /Source="Nicolas_upshift_promotors" /id="U2957" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.543456543456543" /psig=1 /xcortree=2595 /SigmaFactorBS="ctgaaagaataggagatacgaaggatggagcggCTTGcagga acagtcgaaTCCTTGTAAAATGAAGTGTGatgtgattttttttgaaacgtgattttag g" /listShort="S1457, ywzC, S1456, ywfO, ywgA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 3726971..3726977 /Source="Nicolas_upshift_promotors" /id="U2958" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.836163836163836" /psig="0.836163836163836" /xcortree=1045 /SigmaFactorBS="cgctccatccttcgtatctcctattctttcagccaattTGTA TAAatattttccaacctGGACATTCTAATaccatgaaaagaaaaatgggagttgagat a" /listShort="rsfA, S1458" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3726992..3727003 /Source="Nicolas_upshift_promotors" /id="U2958" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.836163836163836" /psig="0.836163836163836" /xcortree=1045 /SigmaFactorBS="cgctccatccttcgtatctcctattctttcagccaattTGTA TAAatattttccaacctGGACATTCTAATaccatgaaaagaaaaatgggagttgagat a" /listShort="rsfA, S1458" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3726993 /Source="Nicolas_upshifts" /id="U2958" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.836163836163836" /psig="0.836163836163836" /xcortree=1045 /SigmaFactorBS="cgctccatccttcgtatctcctattctttcagccaattTGTA TAAatattttccaacctGGACATTCTAATaccatgaaaagaaaaatgggagttgagat a" /listShort="rsfA, S1458" /GFF_Attribute="listLong" CDS 3727035..3727811 /gene="psrF" /locus_tag="BSU_37620" /old_locus_tag="BSU37620" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:10629188, 16497325, 22829778" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10629188, 16497325, 22829778; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="prespore-specific transcription regulatory gene" /protein_id="NP_391642.1" /db_xref="EnsemblGenomes-Gn:BSU37620" /db_xref="EnsemblGenomes-Tr:CAB15789" /db_xref="GOA:P39650" /db_xref="InterPro:IPR014243" /db_xref="InterPro:IPR017877" /db_xref="SubtiList:BG10638" /db_xref="UniProtKB/Swiss-Prot:P39650" /translation="MTKQRQDAWSEENDLLLAETVLRHVREGSTQLNAFEEVGDKLNR TSAACGFRWNAVVRHQYEKALQLAKKQRKQRMRALGNGQPAKKRLLYQPPAVDPEIIQ ETAAEEPVKTETPSVENEQPLMSGEHMPFVDESFKEELASLSHLLSPQTPAAAPEMTM NDVIRFLQNYEGNHEQSSALKMENERLKKENQELQNKTEQLEAEVQKLEKDQKTIQED YETLVKIMNRARKLVLFEEDEHASPSFKMDRNGNLEKLAE*" gene 3727035..3727811 /gene="psrF" /locus_tag="BSU_37620" /old_locus_tag="BSU37620" downshifts 3727797 /Source="Nicolas_upshifts" /id="D1951" /incds=0 /nref=14 /ntot=78 /MaxReadThrough="4.08166" /MaxDrop="4.36214" /score="-5.88286948" /energy="-14.4" /TU="U2958" /idTUdmin="U2958" /TUdmin="-3036" /isTUend="FALSE" promotor_-35 3727899..3727906 /Source="Nicolas_upshift_promotors" /id="U2959" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.962037962037962" /psig=1 /xcortree=2969 /SigmaFactorBS="atccccttttctattgagaaaagagaatttcctcATTTTGCA gccggatcagctatTCTTGTAAAATGAGGCCAAGcttatgtgaatctattaagacatg t" /listShort="S1458, ywfI" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3727921..3727940 /Source="Nicolas_upshift_promotors" /id="U2959" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.962037962037962" /psig=1 /xcortree=2969 /SigmaFactorBS="atccccttttctattgagaaaagagaatttcctcATTTTGCA gccggatcagctatTCTTGTAAAATGAGGCCAAGcttatgtgaatctattaagacatg t" /listShort="S1458, ywfI" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 3727925..3732151 /Source="Nicolas_S_feature" /locus_tag="new_3862327_3866553" /HighExp="T1.30H, T2.0H, T1.0H, T2.30H, T0.30H, T3.0H, T3.30H, T4.0H, T5.0H, T0.0H" /AntisenseName="pta" /AntisenseCor="-0.61235087907102503" /AntisenseRegPval="-28.3" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigGF" /TUshortPSig="1, 0.836" /TUlongSig="NA" /TUlongPSig="NA" /label="S1458" upshifts 3727925 /Source="Nicolas_upshifts" /id="U2959" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.962037962037962" /psig=1 /xcortree=2969 /SigmaFactorBS="atccccttttctattgagaaaagagaatttcctcATTTTGCA gccggatcagctatTCTTGTAAAATGAGGCCAAGcttatgtgaatctattaagacatg t" /listShort="S1458, ywfI" /GFF_Attribute="listLong" CDS complement(3727955..3728845) /gene="ywfM" /locus_tag="BSU_37630" /old_locus_tag="BSU37630" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative toxic excess metabolite exporter" /protein_id="NP_391643.1" /db_xref="EnsemblGenomes-Gn:BSU37630" /db_xref="EnsemblGenomes-Tr:CAB15790" /db_xref="GOA:P39649" /db_xref="InterPro:IPR000620" /db_xref="InterPro:IPR004779" /db_xref="SubtiList:BG10637" /db_xref="UniProtKB/Swiss-Prot:P39649" /translation="MKGNIYSLFVLIAAFFWGTTGTVQALAPESATPLAFGAFRLLIG GSAMLLAVWISRELHVKNWAWPLVFLAAVCMACYQPLFFTAVKETGIAVGTVIAIGSA PIIAGTLEWAVLKKRPRNSWWIATVLALAGCWLLFSDSSNVRIDVAGVLMALGAGASF AGYTLISKAMMKTQPPRATSAVVFMISAILLTPLLWQLDISWILTPRGLGTSLYIGLI ATCAAYFLFAKGLTGVPASAAVTLSLAEPLTASLLGVFFIGEMLSPSSWLGIALMMLG LLVISAAPRKQKTAEAAHMS*" gene complement(3727955..3728845) /gene="ywfM" /locus_tag="BSU_37630" /old_locus_tag="BSU37630" promotor_no_box complement(3728845..3728945) /Source="Nicolas_upshift_promotors" /id="U2960" /multdbtbs="-" /comp="M21" /sig="Sig-" /pcomp="0.568431568431568" /psig="0.136863136863137" /xcortree=1729 /SigmaFactorBS="taatcttattttcagataagtccttcttacatacagataacc acgacaaaaagaaaaacgataaaatgacatcagcatccatattaaaggggagaggcag a" /listShort="ywfM" /GFF_Attribute="listLong" /label="promotor_no_box" upshifts complement(3728885) /Source="Nicolas_upshifts" /id="U2960" /multdbtbs="-" /comp="M21" /sig="Sig-" /pcomp="0.568431568431568" /psig="0.136863136863137" /xcortree=1729 /SigmaFactorBS="taatcttattttcagataagtccttcttacatacagataacc acgacaaaaagaaaaacgataaaatgacatcagcatccatattaaaggggagaggcag a" /listShort="ywfM" /GFF_Attribute="listLong" CDS complement(3729013..3729858) /gene="lipL" /locus_tag="BSU_37640" /old_locus_tag="BSU37640" /function="4: Biosynthesis of cofactors, prosthetic groups, and carriers" /experiment="publication(s) with functional evidences, PMID:21338420, 21338421" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 21338420, 21338421; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="amidotransferase of the octanoyl moiety from octanoyl-GcvH to the E2 subunit of pyruvate dehydrogenase" /protein_id="NP_391644.1" /db_xref="EnsemblGenomes-Gn:BSU37640" /db_xref="EnsemblGenomes-Tr:CAB15791" /db_xref="GOA:P39648" /db_xref="InterPro:IPR004143" /db_xref="InterPro:IPR024897" /db_xref="SubtiList:BG10636" /db_xref="UniProtKB/Swiss-Prot:P39648" /translation="MANQPIDLLMQPKWRVIDQSSLGPLFDAKQSFAMDDTLCMSVGK GVSPATARSWVHHDTIVLGIQDTRLPFLQDGISLLESEGYRVIVRNSGGLAVVLDDGV LNISLIFEDEKKGIDIDKGYEAMVELMRRMLRPYNAKIEAYEIEGSYCPGSYDLSING KKFAGISQRRVRGGVAVQIYLCADKSGSERADLIRRFYQAALKDKQNDKKGVYPEIRP ETMASLSELLQKDISVQDLMFALLTELKALSTHLYSAGLSIDEEMEFEKNLVRMAERN AKVFG*" gene complement(3729013..3729858) /gene="lipL" /locus_tag="BSU_37640" /old_locus_tag="BSU37640" downshifts complement(3729176) /Source="Nicolas_upshifts" /id="D1952" /incds=1 /nref=4 /ntot=180 /MaxReadThrough="3.21908" /MaxDrop="3.30122" /score="31.9003746" /energy="-18.6" /TU="U2961" /idTUdmin="U2961" /TUdmin="-27" /isTUend="FALSE" CDS complement(3729907..3730806) /gene="cysL" /locus_tag="BSU_37650" /old_locus_tag="BSU37650" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:12169591" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12169591; Product type r: regulator" /codon_start=1 /transl_table=11 /product="regulator of sulfur assimilation CysL, activatescysJI expression" /protein_id="NP_391645.1" /db_xref="EnsemblGenomes-Gn:BSU37650" /db_xref="EnsemblGenomes-Tr:CAB15792" /db_xref="GOA:P39647" /db_xref="InterPro:IPR000847" /db_xref="InterPro:IPR005119" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG10635" /db_xref="UniProtKB/Swiss-Prot:P39647" /translation="MYYDVLKTFIAVVEEKNFTKAAEKLMISQPSVSLHIKNLEKEFQ TALLNRSPKHFTTTPTGDILYQRAKQMVFLYEQAKAEIYAHHHYVKGELKIAASFTIG EYILPPLLAQLQKLYPELNLDVMIGNTEEVSERVRMLQADIGLIEGHTNENELEIEPF MEDEMCIAAPNQHPLAGRKEISISDLQNEAWVTREKGSGTREYLDHVLSSNGLRPKSM FTISSNQGVKEAVINGMGLSVLSRSVLRKDLIHREISILHINNFSLKRKLSYIHSPLM ENTKNKEIFITMLKSNYQSQLLK*" gene complement(3729907..3730806) /gene="cysL" /locus_tag="BSU_37650" /old_locus_tag="BSU37650" promotor_-10 complement(3730849..3730868) /Source="Nicolas_upshift_promotors" /id="U2961" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.643356643356643" /psig="0.988011988011988" /xcortree=1930 /SigmaFactorBS="ttttttgcgcttctgtatagcccTTCTTTACcaagacggatg atATGAGTACAATAAAGAAAACtaatcataaccatatatttcattaatgacaggggtg g" /listShort="cysL, ywfL" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3730852) /Source="Nicolas_upshifts" /id="U2961" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.643356643356643" /psig="0.988011988011988" /xcortree=1930 /SigmaFactorBS="ttttttgcgcttctgtatagcccTTCTTTACcaagacggatg atATGAGTACAATAAAGAAAACtaatcataaccatatatttcattaatgacaggggtg g" /listShort="cysL, ywfL" /GFF_Attribute="listLong" promotor_-35 complement(3730882..3730889) /Source="Nicolas_upshift_promotors" /id="U2961" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.643356643356643" /psig="0.988011988011988" /xcortree=1930 /SigmaFactorBS="ttttttgcgcttctgtatagcccTTCTTTACcaagacggatg atATGAGTACAATAAAGAAAACtaatcataaccatatatttcattaatgacaggggtg g" /listShort="cysL, ywfL" /GFF_Attribute="listLong" /label="promotor_-35" downshifts complement(3730953) /Source="Nicolas_upshifts" /id="D1953" /incds=0 /nref=222 /ntot=251 /MaxReadThrough="1.96406" /MaxDrop="7.24606" /score="32.3178773" /energy="-17.3" /TU="NA" /idTUdmin="U2962" /TUdmin=0 /isTUend="TRUE" CDS complement(3730953..3731924) /gene="pta" /locus_tag="BSU_37660" /old_locus_tag="BSU37660" /EC_number="2.3.1.8" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:4201530, 10559153, 10809684, 16283428, 17183215, 17233734, 21453533, 23468065, 25355936" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 4201530, 10559153, 10809684, 16283428, 17183215, 17233734, 21453533, 23468065, 25355936; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="phosphotransacetylase" /protein_id="NP_391646.1" /db_xref="EnsemblGenomes-Gn:BSU37660" /db_xref="EnsemblGenomes-Tr:CAB15793" /db_xref="GOA:P39646" /db_xref="InterPro:IPR002505" /db_xref="InterPro:IPR004614" /db_xref="InterPro:IPR012147" /db_xref="PDB:1TD9" /db_xref="PDB:1XCO" /db_xref="SubtiList:BG10634" /db_xref="UniProtKB/Swiss-Prot:P39646" /translation="MADLFSTVQEKVAGKDVKIVFPEGLDERILEAVSKLAGNKVLNP IVIGNENEIQAKAKELNLTLGGVKIYDPHTYEGMEDLVQAFVERRKGKATEEQARKAL LDENYFGTMLVYKGLADGLVSGAAHSTADTVRPALQIIKTKEGVKKTSGVFIMARGEE QYVFADCAINIAPDSQDLAEIAIESANTAKMFDIEPRVAMLSFSTKGSAKSDETEKVA DAVKIAKEKAPELTLDGEFQFDAAFVPSVAEKKAPDSEIKGDANVFVFPSLEAGNIGY KIAQRLGNFEAVGPILQGLNMPVNDLSRGCNAEDVYNLALITAAQAL*" gene complement(3730953..3731924) /gene="pta" /locus_tag="BSU_37660" /old_locus_tag="BSU37660" promotor_-10 complement(3731959..3731978) /Source="Nicolas_upshift_promotors" /id="U2962" /multdbtbs="SigA" /comp="M16" /sig="SigA" /pcomp="0.808191808191808" /psig="0.974025974025974" /xcortree=2697 /SigmaFactorBS="tagaaaaataagatttttttatgaaagcgctataatgaaagt tggcTGTTTgaatttgattggaagAAGAGTATGCTAGTAAAAGAaagcgtttttgtaa c" /listShort="pta" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3731984) /Source="Nicolas_upshifts" /id="U2962" /multdbtbs="SigA" /comp="M16" /sig="SigA" /pcomp="0.808191808191808" /psig="0.974025974025974" /xcortree=2697 /SigmaFactorBS="tagaaaaataagatttttttatgaaagcgctataatgaaagt tggcTGTTTgaatttgattggaagAAGAGTATGCTAGTAAAAGAaagcgtttttgtaa c" /listShort="pta" /GFF_Attribute="listLong" promotor_-35 complement(3731994..3731998) /Source="Nicolas_upshift_promotors" /id="U2962" /multdbtbs="SigA" /comp="M16" /sig="SigA" /pcomp="0.808191808191808" /psig="0.974025974025974" /xcortree=2697 /SigmaFactorBS="tagaaaaataagatttttttatgaaagcgctataatgaaagt tggcTGTTTgaatttgattggaagAAGAGTATGCTAGTAAAAGAaagcgtttttgtaa c" /listShort="pta" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(3732072..3732083) /Source="Nicolas_upshift_promotors" /id="U2963" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=874 /SigmaFactorBS="ttctactgtggagaaaccttgaacatcccttcCGTATAActc catcaaaataGAAGAACCTATAagggaagattgagtcacttaaattagttagaaaaat a" /listShort="pta" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3732075) /Source="Nicolas_upshifts" /id="U2963" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=874 /SigmaFactorBS="ttctactgtggagaaaccttgaacatcccttcCGTATAActc catcaaaataGAAGAACCTATAagggaagattgagtcacttaaattagttagaaaaat a" /listShort="pta" /GFF_Attribute="listLong" promotor_-35 complement(3732097..3732103) /Source="Nicolas_upshift_promotors" /id="U2963" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=874 /SigmaFactorBS="ttctactgtggagaaaccttgaacatcccttcCGTATAActc catcaaaataGAAGAACCTATAagggaagattgagtcacttaaattagttagaaaaat a" /listShort="pta" /GFF_Attribute="listLong" /label="promotor_-35" misc_feature 3732146..3732165 /Source="Nicolas_upshift_promotors" /id="U2964" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.821178821178821" /psig=1 /xcortree=1605 /SigmaFactorBS="ggagttatacggaagggatgttcaaggtttctccacagtaga atcggataaacTATGGTATAGTGAAGGCAATcatgaaaagataatgggagtgaagata a" /listShort="ywfI, ywfH" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 3732153 /Source="Nicolas_upshifts" /id="U2964" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.821178821178821" /psig=1 /xcortree=1605 /SigmaFactorBS="ggagttatacggaagggatgttcaaggtttctccacagtaga atcggataaacTATGGTATAGTGAAGGCAATcatgaaaagataatgggagtgaagata a" /listShort="ywfI, ywfH" /GFF_Attribute="listLong" CDS 3732194..3732958 /gene="hemQ" /locus_tag="BSU_37670" /old_locus_tag="BSU37670" /EC_number="4.1.-.-" /function="4.3: Heme, porphyrin, and cobalamin" /experiment="publication(s) with functional evidences, PMID:15317589, 16403788, 20543190, 25711532, 26083961, 27599156, 27758026, 27597779, 27936663, 27982566" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15317589, 16403788, 20543190, 25711532, 26083961, 27599156, 27758026, 27597779, 27936663, 27982566; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="iron-coproporphyrin (coproheme) decarboxylase" /protein_id="NP_391647.3" /db_xref="EnsemblGenomes-Gn:BSU37670" /db_xref="EnsemblGenomes-Tr:CAB15794" /db_xref="GOA:P39645" /db_xref="InterPro:IPR010644" /db_xref="InterPro:IPR011008" /db_xref="InterPro:IPR031332" /db_xref="SubtiList:BG10633" /db_xref="UniProtKB/Swiss-Prot:P39645" /translation="MSEQQMTNEAAKTLDGWYALHDFRTMDWASWKLLSSDERQSIIH EFTGLLEKWGVAQKEGKGSQTLYSIVGQKADFMLMILRPTMEELNQIELEFNKSRLAE FTIPAYSYVSVVELSNYLASGDGDPYENPHVRARLYPELPESKYVCFYPMDKRRSGND NWYMLSMEERRNLMRSHGLIGRSYAGKVKQIITGSVGFDDYEWGVTLFSDDVLQFKKL VYEMRFDEVSARYGEFGSFFVGNHLSLDTLPQFLYV*" gene 3732194..3732958 /gene="hemQ" /locus_tag="BSU_37670" /old_locus_tag="BSU37670" downshifts 3732945 /Source="Nicolas_upshifts" /id="D1954" /incds=0 /nref=155 /ntot=246 /MaxReadThrough="5.49286" /MaxDrop="6.26609" /score="19.319449" /energy="-14.5" /TU="U2964" /idTUdmin="U2959" /TUdmin=0 /isTUend="TRUE" promotor_-35 3733021..3733027 /Source="Nicolas_upshift_promotors" /id="U2965" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.383616383616384" /psig="0.999000999001" /xcortree=2901 /SigmaFactorBS="ttcaattctcctttatcagaatttaaataaaATTTGCTattt tcttcgtttTTTCTTACGATGTAGATAATaatccatttttttcaaaggggtgcagtta t" /listShort="ywfH" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3733041..3733060 /Source="Nicolas_upshift_promotors" /id="U2965" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.383616383616384" /psig="0.999000999001" /xcortree=2901 /SigmaFactorBS="ttcaattctcctttatcagaatttaaataaaATTTGCTattt tcttcgtttTTTCTTACGATGTAGATAATaatccatttttttcaaaggggtgcagtta t" /listShort="ywfH" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3733050 /Source="Nicolas_upshifts" /id="U2965" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.383616383616384" /psig="0.999000999001" /xcortree=2901 /SigmaFactorBS="ttcaattctcctttatcagaatttaaataaaATTTGCTattt tcttcgtttTTTCTTACGATGTAGATAATaatccatttttttcaaaggggtgcagtta t" /listShort="ywfH" /GFF_Attribute="listLong" CDS 3733091..3733870 /gene="bacG" /locus_tag="BSU_37680" /old_locus_tag="BSU37680" /EC_number="1.3.1.-" /function="16.8: Protect" /function="16.4: Excrete" /experiment="publication(s) with functional evidences, PMID:12372825, 20052993, 23519407, 25644640" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12372825, 20052993, 23519407, 25644640; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="cyclohexenol-containing tetrahydro-4-hydroxyphenylpyruvate H(4)HPP in bacilysin synthesis" /protein_id="NP_391648.1" /db_xref="EnsemblGenomes-Gn:BSU37680" /db_xref="EnsemblGenomes-Tr:CAB15795" /db_xref="GOA:P39644" /db_xref="InterPro:IPR002347" /db_xref="InterPro:IPR036291" /db_xref="PDB:3U49" /db_xref="PDB:3U4C" /db_xref="PDB:3U4D" /db_xref="SubtiList:BG10632" /db_xref="UniProtKB/Swiss-Prot:P39644" /translation="MSKRTAFVMGASQGIGKAIALKLADQHFSLVINSRNLDNIESVK EDILAKHPEASVIVLAGDMSDQHTRAGIFQKIESQCGRLDVLINNIPGGAPDTFDNCN IEDMTATFTQKTVAYIDAIKRASSLMKQNEFGRIINIVGNLWKEPGANMFTNSMMNAA LINASKNISIQLAPHNITVNCLNPGFIATDRYHQFVENVMKKNSISKQKAEEQIASGI PMKRVGSAEETAALAAFLASEEASYITGQQISADGGSMKSI*" gene 3733091..3733870 /gene="bacG" /locus_tag="BSU_37680" /old_locus_tag="BSU37680" downshifts 3733847 /Source="Nicolas_upshifts" /id="D1955" /incds=0 /nref=84 /ntot=226 /MaxReadThrough="3.12719" /MaxDrop="4.87473" /score="3.07615905" /energy="-11.9" /TU="U2965" /idTUdmin="U2964" /TUdmin=0 /isTUend="TRUE" CDS complement(3733885..3735084) /gene="bacF" /locus_tag="BSU_37690" /old_locus_tag="BSU37690" /function="16.4: Excrete" /function="16.11: Scavenge (Catabolism)" /function="16.2: Construct biomass (Anabolism)" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:12372825, 12670965, 15609023, 20052993, 18957859, 19061923, 25261512, 25472439, 26284661" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12372825, 12670965, 15609023, 20052993, 18957859, 19061923, 25261512, 25472439, 26284661; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="phenylalanine aminotransferase forming tetrahydrotyrosine in bacilysin synthesis" /protein_id="NP_391649.1" /db_xref="EnsemblGenomes-Gn:BSU37690" /db_xref="EnsemblGenomes-Tr:CAB15796" /db_xref="GOA:P39643" /db_xref="InterPro:IPR004838" /db_xref="InterPro:IPR004839" /db_xref="InterPro:IPR015421" /db_xref="InterPro:IPR015422" /db_xref="InterPro:IPR015424" /db_xref="SubtiList:BG10631" /db_xref="UniProtKB/Swiss-Prot:P39643" /translation="MEITPSDVIKTLPRQEFSLVFQKVKEMEKTGAHIINLGQGNPDL PTPPHIVEALREASLNPSFHGYGPFRGYPFLKEAIAAFYKREYGVTINPETEVALFGG GKAGLYVLTQCLLNPGDIALVPNPGYPEYLSGITMARAELYEMPLYEENGYLPDFEKI DPAVLEKAKLMFLNYPNNPTGAVADAAFYAKAAAFAKEHNIHLIHDFAYGAFEFDQKP ASFLEAEDAKTVGAELYSFSKTFNMAGWRMAFAVGNEKIIQAVNEFQDHVFVGMFGGL QQAASAALSGDPEHTESLKRIYKERIDFFTALCEKELGWKMEKPKGTFYVWAEIPNTF ETSHQFSDYLLEHAHVVVTPGEIFGSNGKRHVRISMVSKQEDLREFVTRIQKLNLPFG SLQETSR*" gene complement(3733885..3735084) /gene="bacF" /locus_tag="BSU_37690" /old_locus_tag="BSU37690" CDS complement(3735085..3736269) /gene="bacE" /locus_tag="BSU_37700" /old_locus_tag="BSU37700" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:12372825, 15609023, 15849754, 16850406, 18957859, 19061923, 25261512, 25472439, 26284661" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12372825, 15609023, 15849754, 16850406, 18957859, 19061923, 25261512, 25472439, 26284661; Product type t: transporter" /codon_start=1 /transl_table=11 /product="efflux protein for bacilysin excretion, self-protection against bacilysin" /protein_id="NP_391650.1" /db_xref="EnsemblGenomes-Gn:BSU37700" /db_xref="EnsemblGenomes-Tr:CAB15797" /db_xref="GOA:P39642" /db_xref="InterPro:IPR011701" /db_xref="InterPro:IPR020846" /db_xref="InterPro:IPR022324" /db_xref="InterPro:IPR036259" /db_xref="SubtiList:BG10630" /db_xref="UniProtKB/Swiss-Prot:P39642" /translation="MKQLKPNSKYLLYGQALSFMGDYCVLPALLILSTYYHDYWVTSG VIVVRSIPMVFQPFLGVLVDRLDRIKIMLWTDIIRGIIFLGLTFLPKGEYPLIFLALL FITYGSGVFFNPARLAVMSSLESDIKSINTLFAKATTISIIVGAAAGGLFLLGGSVEL AVAFNGVTYLVSAFFISRIKLQFVPIQSENIKEAFQSFKEGLKEIKTNSFVLNAMFTM ITMALLWGVVYSYFPIVSRFLGDGEIGNFILTFCIGFGGFIGAALVSKWGFNNNRGLT YFTVLSIVSLALFLFTPIFAVSVIAAILFFIAMEYGEVLAKVKVQENAANQIQGRIFS VAEASIGLCISIGSMFINILSAPVIMGLIVVIVCGLFLHTKLVNKSFLERDNKTEQKG VF*" gene complement(3735085..3736269) /gene="bacE" /locus_tag="BSU_37700" /old_locus_tag="BSU37700" CDS complement(3736266..3737684) /gene="bacD" /locus_tag="BSU_37710" /old_locus_tag="BSU37710" /EC_number="6.3.2.49" /function="16.8: Protect" /function="16.4: Excrete" /experiment="publication(s) with functional evidences, PMID:15609023, 16030213, 18957859, 19061923, 22298000, 22407814, 24702628, 25261512, 25472439, 26284661" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15609023, 16030213, 18957859, 19061923, 22298000, 22407814, 24702628, 25261512, 25472439, 26284661; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="alanine-anticapsin ligase" /protein_id="NP_391651.1" /db_xref="EnsemblGenomes-Gn:BSU37710" /db_xref="EnsemblGenomes-Tr:CAB15798" /db_xref="GOA:P39641" /db_xref="InterPro:IPR011761" /db_xref="PDB:3VMM" /db_xref="PDB:3WNZ" /db_xref="PDB:3WO0" /db_xref="PDB:3WO1" /db_xref="SubtiList:BG10629" /db_xref="UniProtKB/Swiss-Prot:P39641" /translation="MERKTVLVIADLGGCPPHMFYKSAAEKYNLVSFIPRPFAITASH AALIEKYSVAVIKDKDYFKSLADFEHPDSIYWAHEDHNKPEEEVVEQIVKVAEMFGAD AITTNNELFIAPMAKACERLGLRGAGVQAAENARDKNKMRDAFNKAGVKSIKNKRVTT LEDFRAALEEIGTPLILKPTYLASSIGVTLITDTETAEDEFNRVNDYLKSINVPKAVT FEAPFIAEEFLQGEYGDWYQTEGYSDYISIEGIMADGEYFPIAIHDKTPQIGFTETSH ITPSILDEEAKKKIVEAAKKANEGLGLQNCATHTEIKLMKNREPGLIESAARFAGWNM IPNIKKVFGLDMAQLLLDVLCFGKDADLPDGLLDQEPYYVADCHLYPQHFKQNGQIPE TAEDLVIEAIDIPDGLLKGDTEIVSFSAAAPGTSVDLTLFEAFNSIAAFELKGSNSQD VAESIRQIQQHAKLTAKYVLPV*" gene complement(3736266..3737684) /gene="bacD" /locus_tag="BSU_37710" /old_locus_tag="BSU37710" CDS complement(3737703..3738464) /gene="bacC" /locus_tag="BSU_37720" /old_locus_tag="BSU37720" /EC_number="1.1.1.385" /function="16.8: Protect" /function="16.4: Excrete" /experiment="publication(s) with functional evidences, PMID:12372825, 15609023, 18957859, 19061923, 23317005, 25261512, 25472439, 26284661, 28158843" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12372825, 15609023, 18957859, 19061923, 23317005, 25261512, 25472439, 26284661, 28158843; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="dihydroanticapsin 7-dehydrogenase" /protein_id="NP_391652.2" /db_xref="EnsemblGenomes-Gn:BSU37720" /db_xref="EnsemblGenomes-Tr:CAB15799" /db_xref="GOA:P39640" /db_xref="InterPro:IPR002347" /db_xref="InterPro:IPR020904" /db_xref="InterPro:IPR036291" /db_xref="PDB:5ITV" /db_xref="PDB:5ITW" /db_xref="SubtiList:BG10628" /db_xref="UniProtKB/Swiss-Prot:P39640" /translation="MNLTDKTVLITGGASGIGYAAVQAFLGQQANVVVADIDEAQGEA MVRKENNDRLHFVQTDITDEAACQHAVESAVHTFGGLDVLINNAGIEIVAPIHEMELS DWNKVLQVNLTGMFLMSKHALKHMLAAGKGNIINTCSVGGLVAWPDIPAYNASKGGVL QLTKSMAVDYAKHQIRVNCVCPGIIDTPLNEKSFLENNEGTLEEIKKEKAKVNPLLRL GKPEEIANVMLFLASDLSSYMTGSAITADGGYTAQ*" gene complement(3737703..3738464) /gene="bacC" /locus_tag="BSU_37720" /old_locus_tag="BSU37720" CDS complement(3738467..3739174) /gene="bacB" /locus_tag="BSU_37730" /old_locus_tag="BSU37730" /EC_number="5.3.3.19" /function="16.4: Excrete" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:12372825, 14697267, 15609023, 15628860, 18957859, 19061923, 19776011, 20445239, 22483065, 22765234, 25261512, 25472439, 26284661" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12372825, 14697267, 15609023, 15628860, 18957859, 19061923, 19776011, 20445239, 22483065, 22765234, 25261512, 25472439, 26284661; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="3-((4R)-4-hydroxycyclohexa-1, 5-dien-1-yl)-2-oxopropanoate isomerase" /protein_id="NP_391653.1" /db_xref="EnsemblGenomes-Gn:BSU37730" /db_xref="EnsemblGenomes-Tr:CAB15800" /db_xref="GOA:P39639" /db_xref="InterPro:IPR011051" /db_xref="InterPro:IPR013096" /db_xref="InterPro:IPR014710" /db_xref="PDB:3H7J" /db_xref="PDB:3H7Y" /db_xref="PDB:3H9A" /db_xref="SubtiList:BG10627" /db_xref="UniProtKB/Swiss-Prot:P39639" /translation="MKTKEDMQELYFPTPKLIEWENGVRQYSTVRGDTEVLMSYVPPH TNVEPHQHKEVQIGMVVSGELMMTVGDVTRKMTALESAYIAPPHVPHGARNDTDQEVI AIDIKRLKADETYTSPEDYFLDIFKTRDLLPGMEVTFFVEDWVEIMLAKIPGNGGEMP FHKHRNEQIGICIGGGYDMTVEGCTVEMKFGTAYFCEPREDHGAINRSEKESKSINIF FPPRYNRAKAKKMKADE*" gene complement(3738467..3739174) /gene="bacB" /locus_tag="BSU_37730" /old_locus_tag="BSU37730" misc_feature complement(3739070..3739071) /Source="Nicolas_upshift_promotors" /id="U2966" /multdbtbs="-" /comp="M21" /sig="Sig-" /pcomp="0.362637362637363" /psig="0.346653346653347" /xcortree=314 /SigmaFactorBS="cgaaattaattgaatgggaaaacggagtgaggcagtattcaa ccgtacgaggggatactgAAgtattaatgtcttacgtcccgccgcataccaatgttga a" /listShort="bacC, bacD, bacE, bacF" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(3739071) /Source="Nicolas_upshifts" /id="U2966" /multdbtbs="-" /comp="M21" /sig="Sig-" /pcomp="0.362637362637363" /psig="0.346653346653347" /xcortree=314 /SigmaFactorBS="cgaaattaattgaatgggaaaacggagtgaggcagtattcaa ccgtacgaggggatactgAAgtattaatgtcttacgtcccgccgcataccaatgttga a" /listShort="bacC, bacD, bacE, bacF" /GFF_Attribute="listLong" CDS complement(3739164..3739778) /gene="bacA" /locus_tag="BSU_37740" /old_locus_tag="BSU37740" /EC_number="4.1.1.100" /function="16.4: Excrete" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:12372825, 15609023, 19776011, 18957859, 19061923, 20052993, 20863139, 25261512, 25472439, 26284661" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12372825, 15609023, 19776011, 18957859, 19061923, 20052993, 20863139, 25261512, 25472439, 26284661; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="prephenate decarboxylase" /protein_id="NP_391654.1" /db_xref="EnsemblGenomes-Gn:BSU37740" /db_xref="EnsemblGenomes-Tr:CAB15801" /db_xref="GOA:P39638" /db_xref="SubtiList:BG10626" /db_xref="UniProtKB/Swiss-Prot:P39638" /translation="MIILDNSIQTKKRTDSLSKLITVNTLGPEGTSSEYAAKHFISNF TLLQGLNSKLSLHDTFESCIERTLQSPLEYTIVPHAYDGIKHFYMRPDLQLLQIFRCD TPMYGLAVRPDFEFRDDMLDTSVIVSHPSPINLIKYFTRKDVRFKLVNSTSQAARKVK EGLYDIALTNELARQKYGLTFVKTFKSIPMSWSLFGKGDVDDEN*" gene complement(3739164..3739778) /gene="bacA" /locus_tag="BSU_37740" /old_locus_tag="BSU37740" promotor_-35 3739336..3739342 /Source="Nicolas_upshift_promotors" /id="U2967" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.996003996003996" /psig="0.996003996003996" /xcortree=185 /SigmaFactorBS="cttgcggcttgactggttgaattgactAGTTTGAaacgaaca tctttgcGGGTAAAATATTTTATTAAattaataggtgaaggatgtgaaacaataacag a" /listShort="S1459" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3739358..3739376 /Source="Nicolas_upshift_promotors" /id="U2967" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.996003996003996" /psig="0.996003996003996" /xcortree=185 /SigmaFactorBS="cttgcggcttgactggttgaattgactAGTTTGAaacgaaca tctttgcGGGTAAAATATTTTATTAAattaataggtgaaggatgtgaaacaataacag a" /listShort="S1459" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 3739369..3739980 /Source="Nicolas_S_feature" /locus_tag="new_3873771_3874382" /HighExp="Etha, Salt, Gly, Heat, C30, LPhT, HiTm, C90, S8, M/G" /AntisenseName="bacA" /AntisenseCor="9.8443047207874598E-2" /AntisenseRegPval="-1" /CDS_PredictionProba="NA" /TUshortSig="SigB" /TUshortPSig="0.996" /TUlongSig="NA" /TUlongPSig="NA" /label="S1459" upshifts 3739369 /Source="Nicolas_upshifts" /id="U2967" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.996003996003996" /psig="0.996003996003996" /xcortree=185 /SigmaFactorBS="cttgcggcttgactggttgaattgactAGTTTGAaacgaaca tctttgcGGGTAAAATATTTTATTAAattaataggtgaaggatgtgaaacaataacag a" /listShort="S1459" /GFF_Attribute="listLong" promotor_-10 complement(3739801..3739820) /Source="Nicolas_upshift_promotors" /id="U2968" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.993006993006993" /psig=1 /xcortree=2947 /SigmaFactorBS="tttgtatgggaataattatcaatattttcaaaaaaCATTGAC AgttcaatttccactGGATAAAATTTACTTAAAATtttaaaagattggttggtgctca t" /listShort="bacA, bacB, bacC, bacD, bacE, bacF" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3739817) /Source="Nicolas_upshifts" /id="U2968" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.993006993006993" /psig=1 /xcortree=2947 /SigmaFactorBS="tttgtatgggaataattatcaatattttcaaaaaaCATTGAC AgttcaatttccactGGATAAAATTTACTTAAAATtttaaaagattggttggtgctca t" /listShort="bacA, bacB, bacC, bacD, bacE, bacF" /GFF_Attribute="listLong" promotor_-35 complement(3739835..3739842) /Source="Nicolas_upshift_promotors" /id="U2968" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.993006993006993" /psig=1 /xcortree=2947 /SigmaFactorBS="tttgtatgggaataattatcaatattttcaaaaaaCATTGAC AgttcaatttccactGGATAAAATTTACTTAAAATtttaaaagattggttggtgctca t" /listShort="bacA, bacB, bacC, bacD, bacE, bacF" /GFF_Attribute="listLong" /label="promotor_-35" downshifts complement(3739929) /Source="Nicolas_upshifts" /id="D1956" /incds=0 /nref=1 /ntot=33 /MaxReadThrough="2.28302" /MaxDrop="5.44594" /score="19.4538123" /energy="-5.1" /TU="NA" /idTUdmin="U2969" /TUdmin=902 /isTUend="FALSE" CDS complement(3739930..3741168) /gene="ywfA" /locus_tag="BSU_37750" /old_locus_tag="BSU37750" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15609023, 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative efflux transporter" /protein_id="NP_391655.1" /db_xref="EnsemblGenomes-Gn:BSU37750" /db_xref="EnsemblGenomes-Tr:CAB15802" /db_xref="GOA:P39637" /db_xref="InterPro:IPR011701" /db_xref="InterPro:IPR020846" /db_xref="InterPro:IPR036259" /db_xref="SubtiList:BG10625" /db_xref="UniProtKB/Swiss-Prot:P39637" /translation="MNSNQNNDIKTKHHFPLLLALALTMGVFAAGSEELVISPLLPDL AKAFSSDVSVLALSISIYGVMIFIGAPLLVPLGDKYSRELSLLAGLMIFIIGTVICAL AQNIFFFFLGRALSGLAAGAFVPTAYAVVGDRVPYTYRGKVMGLIVSSWSLALIFGVP LGSFIGGVLHWRWTFWIFALMGVLVVLLILLEMRRHAQHKNSGKEEIEEPAGTFRDAL KVPRVPVYITITFCNMIGFYGMYSFLGTYLQDVFTGGNTAAGLFIMIYGIGFSMSVIT GKIADRIGKMRSLLIALGVISVLLACLPYAPASMFLLIASLFIWGLMQSLTVTLLSTI LSDCSERHRGKVMVFYSLASNLAVTLGSALMGPVYVAYGYAAVGLICAAITVLGFVLS VFAYKKYGKLEQKADQSLSQ*" gene complement(3739930..3741168) /gene="ywfA" /locus_tag="BSU_37750" /old_locus_tag="BSU37750" promotor_-10 complement(3741210..3741229) /Source="Nicolas_upshift_promotors" /id="U2969" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.72027972027972" /psig="0.988011988011988" /xcortree=756 /SigmaFactorBS="gaaaataataaaacttataaatatttcgttcgaaTTGTAAAT agagaaaaaacAATGCTAAACTATAATACAActttatgataagaagattatggaagag g" /listShort="ywfA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3741222) /Source="Nicolas_upshifts" /id="U2969" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.72027972027972" /psig="0.988011988011988" /xcortree=756 /SigmaFactorBS="gaaaataataaaacttataaatatttcgttcgaaTTGTAAAT agagaaaaaacAATGCTAAACTATAATACAActttatgataagaagattatggaagag g" /listShort="ywfA" /GFF_Attribute="listLong" promotor_-35 complement(3741241..3741248) /Source="Nicolas_upshift_promotors" /id="U2969" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.72027972027972" /psig="0.988011988011988" /xcortree=756 /SigmaFactorBS="gaaaataataaaacttataaatatttcgttcgaaTTGTAAAT agagaaaaaacAATGCTAAACTATAATACAActttatgataagaagattatggaagag g" /listShort="ywfA" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3741378..3742790) /gene="rocC" /locus_tag="BSU_37760" /old_locus_tag="BSU37760" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2b: Function from indirect experimental evidences (e.g. phenotypes); PubMedId: 7540694, 8113162, 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="basic aminoacid permease" /protein_id="NP_391656.1" /db_xref="EnsemblGenomes-Gn:BSU37760" /db_xref="EnsemblGenomes-Tr:CAB15803" /db_xref="GOA:P39636" /db_xref="InterPro:IPR002293" /db_xref="InterPro:IPR004840" /db_xref="InterPro:IPR004841" /db_xref="SubtiList:BG10624" /db_xref="UniProtKB/Swiss-Prot:P39636" /translation="MQNHKNELQRSMKSRHLFMIALGGVIGTGLFLGSGFTISQAGPL GAIAAYIIGGFLMYLVMLCLGELAVAMPVAGSFQAYATKFLGQSTGFMIGWLYWFSWA NTVGLELTSAGILMQRWLPSVPIWIWCLVFGIVIFLINALSVRSFAEMEFWFSSIKVA AIILFIVIGGAAVFGLIDFKGGQETPFLSNFMTDRGLFPNGVLAVMFTLVMVNFSFQG TELVGIAAGESESPEKTLPKSIRNVIWRTLFFFVLAMFVLVAILPYKTAGVIESPFVA VLDQIGIPFSADIMNFVILTAILSVANSGLYAASRMMWSLSSNQMGPSFLTRLTKKGV PMNALLITLGISGCSLLTSVMAAETVYLWCISISGMVTVVAWMSICASQFFFRRRFLA EGGNVNDLEFRTPLYPLVPILGFCLYGCVLISLIFIPDQRIGLYCGVPIIIFCYAYYH LSIKKRINHETIEKKQTEAQ*" gene complement(3741378..3742790) /gene="rocC" /locus_tag="BSU_37760" /old_locus_tag="BSU37760" downshifts complement(3741385) /Source="Nicolas_upshifts" /id="D1957" /incds=0 /nref=16 /ntot=112 /MaxReadThrough="1.06691" /MaxDrop="5.69562" /score="41.626335" /energy="-15.9" /TU="NA" /idTUdmin="U2971" /TUdmin="-4" /isTUend="TRUE" CDS complement(3742790..3744490) /gene="rocB" /locus_tag="BSU_37770" /old_locus_tag="BSU37770" /EC_number="3.5.1.-" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 8113162; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative N-deacylase involved in arginine and ornithine utilization" /protein_id="NP_391657.1" /db_xref="EnsemblGenomes-Gn:BSU37770" /db_xref="EnsemblGenomes-Tr:CAB15804" /db_xref="GOA:P39635" /db_xref="InterPro:IPR002933" /db_xref="InterPro:IPR012166" /db_xref="SubtiList:BG10623" /db_xref="UniProtKB/Swiss-Prot:P39635" /translation="MQYTKISHMNPAERVEALTASLVSLSSVNGTVGEGTKADFIKEV ITSYPYFQENPSHVWEQAIPNDPYKRKNIFAFIKGHGESRNTVIYHAHLDTVGIEDFG PLKDIAFDCEKLAEYFSRYEFDQDVQRDAKSGEWMFGRGSVDMQSGIAVHLANLLHFS ENLETLPGNVLFMANPDEESQHSGILASISELNRLKKEKQLHYLAAINTDFITPLYDG DQTRYIYTGAAGKLLPCFYIYGREVHVGDTLAGIDPNFISSEITSRLHNNIHLAEKVE GELVLPPSCLYQRDNKESYNVQTAVSTSLYFNCFIYERTAKEMMDLLIEVTEEACRET EQKLSDYYEEYVKRANLPKKHLSWGIQVYSLEQYLEKLRNRGIDPEQCIEQTFKANEH LELRMRCFQAIEELQKLDPDQGAKVILFYAPPYLPHNYLKEDSARDQLLQHVIKEAAD KTAESTGETFVFKKFFPYLADGSFLSLHETDGEIDSFIRNFPGWNMIGTIPFKDIRKL NIPSINMGVYGKDGHKWTERVYKPYTFHVLPLLIQQTTVHLLQSYRMTITAKEPKGEG *" gene complement(3742790..3744490) /gene="rocB" /locus_tag="BSU_37770" /old_locus_tag="BSU37770" misc_feature complement(3743459..3743475) /Source="Nicolas_upshift_promotors" /id="U2970" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.238761238761239" /psig="0.613386613386613" /xcortree=2859 /SigmaFactorBS="ggatttgcttattgaagtcactgaggaagcatgccgggagac agaacaaaaattatCAGATTATTACGAAGAAtatgtaaaaagagccaacctgccaaag a" /listShort="rocC" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(3743471) /Source="Nicolas_upshifts" /id="U2970" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.238761238761239" /psig="0.613386613386613" /xcortree=2859 /SigmaFactorBS="ggatttgcttattgaagtcactgaggaagcatgccgggagac agaacaaaaattatCAGATTATTACGAAGAAtatgtaaaaagagccaacctgccaaag a" /listShort="rocC" /GFF_Attribute="listLong" CDS complement(3744564..3746111) /gene="rocA" /locus_tag="BSU_37780" /old_locus_tag="BSU37780" /EC_number="1.2.1.88" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 11418582, 12634342, 8113162, 9383188, 25355936; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="delta-1-pyrroline-5 carboxylate dehydrogenase" /protein_id="NP_391658.1" /db_xref="EnsemblGenomes-Gn:BSU37780" /db_xref="EnsemblGenomes-Tr:CAB15805" /db_xref="GOA:P39634" /db_xref="InterPro:IPR005932" /db_xref="InterPro:IPR015590" /db_xref="InterPro:IPR016160" /db_xref="InterPro:IPR016161" /db_xref="InterPro:IPR016162" /db_xref="InterPro:IPR029510" /db_xref="SubtiList:BG10622" /db_xref="UniProtKB/Swiss-Prot:P39634" /translation="MTVTYAHEPFTDFTEAKNKTAFGESLAFVNTQLGKHYPLVINGE KIETDRKIISINPANKEEIIGYASTADQELAEKAMQAALQAFDSWKKQRPEHRANILF KAAAILRRRKHEFSSYLVKEAGKPWKEADADTAEAIDFLEFYARQMLKLKEGAPVKSR AGEVNQYHYEALGVGIVISPFNFPLAIMAGTAVAAIVTGNTILLKPADAAPVVAAKFV EVMEEAGLPNGVLNYIPGDGAEIGDFLVEHPKTRFVSFTGSRAVGCRIYERAAKVQPG QKWLKRVIAEMGGKDTVLVDKDADLDLAASSIVYSAFGYSGQKCSAGSRAVIHQDVYD EVVEKAVALTKTLTVGNPEDPDTYMGPVIHEASYNKVMKYIEIGKSEGKLLAGGEGDD SKGYFIQPTIFADVDENARLMQEEIFGPVVAICKARDFDHMLEIANNTEYGLTGALLT KNRAHIERAREDFHVGNLYFNRGCTGAIVGYQPFGGFNMSGTDSKAGGPDYLILHMQA KTTSEAF*" gene complement(3744564..3746111) /gene="rocA" /locus_tag="BSU_37780" /old_locus_tag="BSU37780" downshifts complement(3744571) /Source="Nicolas_upshifts" /id="D1958" /incds=0 /nref=4 /ntot=50 /MaxReadThrough="5.60027" /MaxDrop="3.5628" /score="41.626335" /energy="-15.9" /TU="U2971,U2972" /idTUdmin="U2973" /TUdmin=0 /isTUend="TRUE" upshifts complement(3746155) /Source="Nicolas_upshifts" /id="U2971" /multdbtbs="SigL" /comp="M18" /sig="SigL" /pcomp="0.874125874125874" /psig="0.874125874125874" /xcortree=2703 /SigmaFactorBS="gttcgattcaacaagttttttcagcaaaagacaagaaaaTGG CATGATTCTTGCATTTttattcatatgcgaagatatatttcataacacgagggggact a" /listShort="rocA, rocB, rocC" /GFF_Attribute="listLong" S_feature complement(3746157..3746337) /Source="Nicolas_S_feature" /locus_tag="new_3880559_3880739_c" /HighExp="S0, Lbstat, T1.30H, T2.0H, T1.0H, BI, T2.30H, M0t90, M40t90, HPh" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigL, SigA" /TUshortPSig="0.864, 0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S1460" misc_feature complement(3746158..3746176) /Source="Nicolas_upshift_promotors" /id="U2971" /multdbtbs="SigL" /comp="M18" /sig="SigL" /pcomp="0.874125874125874" /psig="0.874125874125874" /xcortree=2703 /SigmaFactorBS="gttcgattcaacaagttttttcagcaaaagacaagaaaaTGG CATGATTCTTGCATTTttattcatatgcgaagatatatttcataacacgagggggact a" /listShort="rocA, rocB, rocC" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" CDS complement(3746338..3747612) /gene="rocG" /locus_tag="BSU_37790" /old_locus_tag="BSU37790" /EC_number="1.4.1.2" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:9829940, 10468601, 12634342, 15150224, 17183217, 17608797, 18326565, 20630473, 22178969, 22625175, 25711804, 28193334" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9829940, 10468601, 12634342, 15150224, 17183217, 17608797, 18326565, 20630473, 22178969, 22625175, 25711804, 28193334; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="glutamate dehydrogenase" /protein_id="NP_391659.2" /db_xref="EnsemblGenomes-Gn:BSU37790" /db_xref="EnsemblGenomes-Tr:CAB15806" /db_xref="GOA:P39633" /db_xref="InterPro:IPR006095" /db_xref="InterPro:IPR006096" /db_xref="InterPro:IPR006097" /db_xref="InterPro:IPR014362" /db_xref="InterPro:IPR033524" /db_xref="InterPro:IPR033922" /db_xref="InterPro:IPR036291" /db_xref="PDB:3K92" /db_xref="SubtiList:BG10621" /db_xref="UniProtKB/Swiss-Prot:P39633" /translation="MSAKQVSKDEEKEALNLFLSTQTIIKEALRKLGYPGDMYELMKE PQRMLTVRIPVKMDNGSVKVFTGYRSQHNDAVGPTKGGVRFHPEVNEEEVKALSIWMT LKCGIANLPYGGGKGGIICDPRTMSFGELERLSRGYVRAISQIVGPTKDIPAPDVYTN SQIMAWMMDEYSRLREFDSPGFITGKPLVLGGSQGRETATAQGVTICIEEAVKKKGIK LQNARIIIQGFGNAGSFLAKFMHDAGAKVIGISDANGGLYNPDGLDIPYLLDKRDSFG MVTNLFTDVITNEELLEKDCDILVPAAISNQITAKNAHNIQASIVVEAANGPTTIDAT KILNERGVLLVPDILASAGGVTVSYFEWVQNNQGYYWSEEEVAEKLRSVMVSSFETIY QTAATHKVDMRLAAYMTGIRKSAEASRFRGWV*" gene complement(3746338..3747612) /gene="rocG" /locus_tag="BSU_37790" /old_locus_tag="BSU37790" S_feature complement(3747613..3747695) /Source="Nicolas_S_feature" /locus_tag="new_3882015_3882097_c" /HighExp="S0, Lbstat, T1.30H, T2.0H, T1.0H, BI, T2.30H, M0t90, M40t90, T0.30H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.83780600000000005" /TUshortSig="SigL, SigA" /TUshortPSig="0.864, 0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S1461" upshifts complement(3747695) /Source="Nicolas_upshifts" /id="U2972" /multdbtbs="SigL" /comp="M18" /sig="SigL" /pcomp="0.864135864135864" /psig="0.864135864135864" /xcortree=393 /SigmaFactorBS="tcagtctctttttttgtggattcaaaagcTGGTACGGATCTT GCATGAtgataagggtgaatccaatgaagaaaggaattggcgggctgattttttaaag c" /listShort="S1461, rocG, S1460, rocA, rocB, rocC" /GFF_Attribute="listLong" misc_feature complement(3747708..3747726) /Source="Nicolas_upshift_promotors" /id="U2972" /multdbtbs="SigL" /comp="M18" /sig="SigL" /pcomp="0.864135864135864" /psig="0.864135864135864" /xcortree=393 /SigmaFactorBS="tcagtctctttttttgtggattcaaaagcTGGTACGGATCTT GCATGAtgataagggtgaatccaatgaagaaaggaattggcgggctgattttttaaag c" /listShort="S1461, rocG, S1460, rocA, rocB, rocC" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" downshifts complement(3747788) /Source="Nicolas_upshifts" /id="D1959" /incds=0 /nref=9 /ntot=144 /MaxReadThrough="4.82066" /MaxDrop="4.13762" /score="22.6949864" /energy="-11.4" /TU="U2973" /idTUdmin="U2977" /TUdmin=369 /isTUend="FALSE" CDS complement(3747789..3748253) /gene="bslB" /locus_tag="BSU_37800" /old_locus_tag="BSU37800" /experiment="publication(s) with functional evidences, PMID:15187182, 28751732" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15187182, 28751732; Product type ph: phenotype" /codon_start=1 /transl_table=11 /product="biofilm protein, member of the processed secretome contributing to biofilm hydrophobicity" /protein_id="NP_391660.1" /db_xref="EnsemblGenomes-Gn:BSU37800" /db_xref="EnsemblGenomes-Tr:CAB15807" /db_xref="GOA:P39632" /db_xref="InterPro:IPR034650" /db_xref="PDB:5MKD" /db_xref="SubtiList:BG10620" /db_xref="UniProtKB/Swiss-Prot:P39632" /translation="MLKRTSFVSSLFISSAVLLSILLPSGQAHAQSASIEAKTVNSTK EWTISDIEVTYKPNAVLSLGAVEFQFPDGFHATTRDSVNGRTLKETQILNDGKTVRLP LTLDLLGASEFDLVMVRKTLPRAGTYTIKGDVVNGLGIGSFYAETQLVIDPR*" gene complement(3747789..3748253) /gene="bslB" /locus_tag="BSU_37800" /old_locus_tag="BSU37800" S_feature complement(3748254..3748364) /Source="Nicolas_S_feature" /locus_tag="new_3882656_3882766_c" /HighExp="C90, S1, S0, MG 150, M9-tran, LPhT, BI, GM 150, Lbtran, GM 120" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigK" /TUshortPSig="0.999, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S1462" promotor_-10 complement(3748346..3748365) /Source="Nicolas_upshift_promotors" /id="U2973" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.964035964035964" /psig="0.999000999001" /xcortree=2719 /SigmaFactorBS="tctcattgaattccaagtgttaatattccttaaaaaaCATTT ACTtccatggaaaatgaTGATAGATTAATTTTTAAGAaaaagaactggtaattcgcga a" /listShort="S1462, yweA, S1461, rocG, S1460, rocA" /listLong="rocB, rocC" /label="promotor_-10" upshifts complement(3748364) /Source="Nicolas_upshifts" /id="U2973" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.964035964035964" /psig="0.999000999001" /xcortree=2719 /SigmaFactorBS="tctcattgaattccaagtgttaatattccttaaaaaaCATTT ACTtccatggaaaatgaTGATAGATTAATTTTTAAGAaaaagaactggtaattcgcga a" /listShort="S1462, yweA, S1461, rocG, S1460, rocA" /listLong="rocB, rocC" promotor_-35 complement(3748380..3748387) /Source="Nicolas_upshift_promotors" /id="U2973" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.964035964035964" /psig="0.999000999001" /xcortree=2719 /SigmaFactorBS="tctcattgaattccaagtgttaatattccttaaaaaaCATTT ACTtccatggaaaatgaTGATAGATTAATTTTTAAGAaaaagaactggtaattcgcga a" /listShort="S1462, yweA, S1461, rocG, S1460, rocA" /listLong="rocB, rocC" /label="promotor_-35" downshifts complement(3748575) /Source="Nicolas_upshifts" /id="D1960" /incds=0 /nref=32 /ntot=80 /MaxReadThrough="3.01999" /MaxDrop="4.92444" /score="6.35246869" /energy="-8.4" /TU="U2977" /idTUdmin="U2977" /TUdmin="-418" /isTUend="FALSE" CDS complement(3748577..3749032) /gene="spsL" /locus_tag="BSU_37810" /old_locus_tag="BSU37810" /EC_number="5.1.3.13" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 25239894; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative dTDP-4-deoxyrhamnose-3,5-epimerase (cell surface and spore coat)" /protein_id="YP_054595.1" /db_xref="EnsemblGenomes-Gn:BSU37810" /db_xref="EnsemblGenomes-Tr:CAE01469" /db_xref="GOA:Q7WY56" /db_xref="InterPro:IPR000888" /db_xref="InterPro:IPR011051" /db_xref="InterPro:IPR014710" /db_xref="SubtiList:BG14195" /db_xref="UniProtKB/Swiss-Prot:Q7WY56" /translation="MIDGVKVKKLMKHSDDRGFFAELVRDDENLLEHFGQASWSKSYP GVIKAFHYHEKQDDLWFFPTGHAQVVLYDLREDSKTKGETDVYYMGEDNPMLLLIPKG VAHGYRVLGETPLTIIYFTTMSYNPDQPDEKRIPWDDETIGFNWNTEFR*" gene complement(3748577..3749032) /gene="spsL" /locus_tag="BSU_37810" /old_locus_tag="BSU37810" misc_feature 3748667..3748686 /Source="Nicolas_upshift_promotors" /id="U2974" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.671328671328671" /psig=1 /xcortree=2855 /SigmaFactorBS="catcatcccacggaattcttttttcatcaggctgatccgggt tatacgacatGGTGGTAAAATAGATAATTGtcagcggcgtctctcccagcactctata t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 3748675 /Source="Nicolas_upshifts" /id="U2974" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.671328671328671" /psig=1 /xcortree=2855 /SigmaFactorBS="catcatcccacggaattcttttttcatcaggctgatccgggt tatacgacatGGTGGTAAAATAGATAATTGtcagcggcgtctctcccagcactctata t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" CDS complement(3749025..3749876) /gene="spsK" /locus_tag="BSU_37820" /old_locus_tag="BSU37820" /EC_number="1.1.1.133" /function="16.13: Shape" /function="16.8: Protect" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative dTDP-4-dehydrorhamnose reductase" /protein_id="NP_391661.3" /db_xref="EnsemblGenomes-Gn:BSU37820" /db_xref="EnsemblGenomes-Tr:CAB15808" /db_xref="GOA:P39631" /db_xref="InterPro:IPR005913" /db_xref="InterPro:IPR029903" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG10619" /db_xref="UniProtKB/Swiss-Prot:P39631" /translation="MTKVLVTGAGGQLGLELCRQLKQAGYEVIALTKKMMNIADQRSV RHSFGHYQPDIVVNSAAFTSVDQCEKELDKAYLINGIGAYYTALESTRIGAQYVHIST DYVFNGKGTQPYREDDPLDPKTIYGKSKRLGEELIRLTTKDSTIIRTSWVYGHGGSNF VETMLKLAETKQELRVVSDQIGSPTYTKDLAEAVIKLFSHPPGIYHVSNSGICSWYEF ATAIMEESGLETAILSVTTEEYGNKTPRPAYSVLSHRAIEEAGIRPRHWREALREYLQ ERSSACD*" gene complement(3749025..3749876) /gene="spsK" /locus_tag="BSU_37820" /old_locus_tag="BSU37820" CDS complement(3749890..3750837) /gene="spsJ" /locus_tag="BSU_37830" /old_locus_tag="BSU37830" /EC_number="4.2.1.46" /function="16.8: Protect" /function="16.5: Explore" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:22960854" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 22960854; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="dTDP-glucose 4,6-dehydratase" /protein_id="NP_391662.1" /db_xref="EnsemblGenomes-Gn:BSU37830" /db_xref="EnsemblGenomes-Tr:CAB15809" /db_xref="GOA:P39630" /db_xref="InterPro:IPR005888" /db_xref="InterPro:IPR016040" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG10618" /db_xref="UniProtKB/Swiss-Prot:P39630" /translation="MAKSYLITGGAGFIGLTFTKLMLRETDARITVLDKLTYASHPEE MEKLKQNSRFRFVKGDISVQEDIDRAFDETYDGVIHFAAESHVDRSISQAEPFITTNV MGTYRLAEAVLKGKAKKLIHISTDEVYGDLKADDPAFTETTPLSPNNPYSASKASSDL LVLSYVKTHKLPAIITRCSNNYGPYQHSEKMIPTIIRHAKQGLPVPLYGDGLQIRDWL FAEDHCRAIKLILEKGTDGEVYNIGGGNERTNKELASVILKHLGCEELFAHVEDRKGH DRRYAINASKLKNELGWRQEVTFEEGIARTIQWYTDNDR*" gene complement(3749890..3750837) /gene="spsJ" /locus_tag="BSU_37830" /old_locus_tag="BSU37830" CDS complement(3750837..3751577) /gene="spsI" /locus_tag="BSU_37840" /old_locus_tag="BSU37840" /EC_number="2.7.7.24" /function="16.8: Protect" /function="16.5: Explore" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:22960854" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 22960854; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="glucose-1-phosphate thymidylyltransferase" /protein_id="NP_391663.1" /db_xref="EnsemblGenomes-Gn:BSU37840" /db_xref="EnsemblGenomes-Tr:CAB15810" /db_xref="GOA:P39629" /db_xref="InterPro:IPR005835" /db_xref="InterPro:IPR005907" /db_xref="InterPro:IPR029044" /db_xref="SubtiList:BG10617" /db_xref="UniProtKB/Swiss-Prot:P39629" /translation="MKGVILAGGNGSRLMPLTKAVNKHLLPVGPYPMIYWSIMKLQEA GIKDILLISQKEHMPQFYKLLGNGEELGVTITYQVQPAASGISDGLSYAKRFTKKESF ILLLGDNIFEDSLKPYTERFEQQGKGAKVLLKEVDDPERFGIAEIDEKNKRIRSIIEK PEQPPTNLCVTGIYMYDAEVFSYIEQISPSKRGELEITDVNNLYIENSQLTYDVLSGW WVDAGTHESLYLASQLVHQALRKGQDEK*" gene complement(3750837..3751577) /gene="spsI" /locus_tag="BSU_37840" /old_locus_tag="BSU37840" promotor_-35 3751595..3751600 /Source="Nicolas_upshift_promotors" /id="U2975" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.89010989010989" /psig="0.89010989010989" /xcortree=953 /SigmaFactorBS="gtgagccgtttcctccggctaaaataacacctttcacattaa cacttccttacaTGCATTtttatatctcttgtTCATATAAATCTTGAAGAAtagctgt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 3751601 /Source="Nicolas_upshifts" /id="U2975" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.89010989010989" /psig="0.89010989010989" /xcortree=953 /SigmaFactorBS="gtgagccgtttcctccggctaaaataacacctttcacattaa cacttccttacaTGCATTtttatatctcttgtTCATATAAATCTTGAAGAAtagctgt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" CDS complement(3751602..3752621) /gene="spsG" /locus_tag="BSU_37850" /old_locus_tag="BSU37850" /function="16.13: Shape" /function="16.8: Protect" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative glycosyltransferase" /protein_id="NP_391664.1" /db_xref="EnsemblGenomes-Gn:BSU37850" /db_xref="EnsemblGenomes-Tr:CAB15811" /db_xref="GOA:P39627" /db_xref="InterPro:IPR007235" /db_xref="SubtiList:BG10615" /db_xref="UniProtKB/Swiss-Prot:P39627" /translation="MHVGIFADGGYEKGMGHVVRMKRLAEGLKQRCLITFYTNQDSEA FLHEEHWQVIVKPELQQHEFILREIKSKKLDLLLFDILGAPAELLKKIKTETDAKIVL FEEKNGKSIQYSDAVINGIYGDIRSRVYVQGNTRIYEGPDYLILHPAFQAAREDYTLK KDCRNILVALGGSDPKQLIFKVLAAADQVPDIKDKNMMFVMGSASPHQEAVRRRIEKK PQYKMIEQTNDMAGLMKQADAAIVAGGISLYEAICIGVPCLVLSQVEHQTATAKTFAD QGAALDLGLGELVPDETLIYQMSRIMSSYPLRLSLHKGGRPLVDGKGIIRVTAILQDL YEQEI*" gene complement(3751602..3752621) /gene="spsG" /locus_tag="BSU_37850" /old_locus_tag="BSU37850" promotor_-10 3751615..3751633 /Source="Nicolas_upshift_promotors" /id="U2975" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.89010989010989" /psig="0.89010989010989" /xcortree=953 /SigmaFactorBS="gtgagccgtttcctccggctaaaataacacctttcacattaa cacttccttacaTGCATTtttatatctcttgtTCATATAAATCTTGAAGAAtagctgt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 3752485..3752494 /Source="Nicolas_upshift_promotors" /id="U2976" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1682 /SigmaFactorBS="acgatgacctgccaatgctcttcatgaAGAAACGCTTcagaa tcctgatTCGTATAAAACGTAATcaagcatcgctgtttgagcccctccgcaagcctct t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3752507..3752522 /Source="Nicolas_upshift_promotors" /id="U2976" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1682 /SigmaFactorBS="acgatgacctgccaatgctcttcatgaAGAAACGCTTcagaa tcctgatTCGTATAAAACGTAATcaagcatcgctgtttgagcccctccgcaagcctct t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3752518 /Source="Nicolas_upshifts" /id="U2976" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1682 /SigmaFactorBS="acgatgacctgccaatgctcttcatgaAGAAACGCTTcagaa tcctgatTCGTATAAAACGTAATcaagcatcgctgtttgagcccctccgcaagcctct t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" CDS complement(3752624..3753346) /gene="spsF" /locus_tag="BSU_37860" /old_locus_tag="BSU37860" /EC_number="2.-.-.-" /function="16.8: Protect" /function="16.5: Explore" /function="16.13: Shape" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative glycosyltransferase" /protein_id="NP_391665.2" /db_xref="EnsemblGenomes-Gn:BSU37860" /db_xref="EnsemblGenomes-Tr:CAB15812" /db_xref="InterPro:IPR003329" /db_xref="InterPro:IPR029044" /db_xref="SubtiList:BG10614" /db_xref="UniProtKB/Swiss-Prot:P39626" /translation="MNDILFIIQARMGSTRLPGKVLRPLGSNRLLDILVHRVRQSAFY QKDRDNLVIATSDKETDDILEAHCIKQGFRVFRGSEERVLDRFVKVIEAVKPSVIIRL TGDNPFVDPELLDVMIQAHFDQGSDYTYILNAPLGICGEVVNANLLIDISRIQALEDQ YQEHVTLYIRNHPALYRVQFLEAPERFRAPQYRLTIDTKEDYESIKALYQKAGERPDV SASELITLLNRNPDAATEREAD*" gene complement(3752624..3753346) /gene="spsF" /locus_tag="BSU_37860" /old_locus_tag="BSU37860" CDS complement(3753339..3754460) /gene="spsE" /locus_tag="BSU_37870" /old_locus_tag="BSU37870" /EC_number="2.5.-.-" /function="16.13: Shape" /function="16.8: Protect" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 12597896, 15774001; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative phosphoenolpyruvate-sugar pyruvyltransferase" /protein_id="NP_391666.1" /db_xref="EnsemblGenomes-Gn:BSU37870" /db_xref="EnsemblGenomes-Tr:CAB15813" /db_xref="GOA:P39625" /db_xref="InterPro:IPR006190" /db_xref="InterPro:IPR013132" /db_xref="InterPro:IPR013785" /db_xref="InterPro:IPR013974" /db_xref="InterPro:IPR036732" /db_xref="PDB:1VLI" /db_xref="SubtiList:BG10613" /db_xref="UniProtKB/Swiss-Prot:P39625" /translation="MAAFQIANKTVGKDAPVFIIAEAGINHDGKLDQAFALIDAAAEA GADAVKFQMFQADRMYQKDPGLYKTAAGKDVSIFSLVQSMEMPAEWILPLLDYCREKQ VIFLSTVCDEGSADLLQSTSPSAFKIASYEINHLPLLKYVARLNRPMIFSTAGAEISD VHEAWRTIRAEGNNQIAIMHCVAKYPAPPEYSNLSVIPMLAAAFPEAVIGFSDHSEHP TEAPCAAVRLGAKLIEKHFTIDKNLPGADHSFALNPDELKEMVDGIRKTEAELKQGIT KPVSEKLLGSSYKTTTAIEGEIRNFAYRGIFTTAPIQKGEAFSEDNIAVLRPGQKPQG LHPRFFELLTSGVRAVRDIPADTGIVWDDILLKDSPFHE*" gene complement(3753339..3754460) /gene="spsE" /locus_tag="BSU_37870" /old_locus_tag="BSU37870" CDS complement(3754460..3755329) /gene="spsD" /locus_tag="BSU_37880" /old_locus_tag="BSU37880" /EC_number="2.3.1.-" /function="16.5: Explore" /function="16.13: Shape" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative TDP-glycosamine N-acetyltransferase" /protein_id="NP_391667.1" /db_xref="EnsemblGenomes-Gn:BSU37880" /db_xref="EnsemblGenomes-Tr:CAB15814" /db_xref="GOA:P39624" /db_xref="InterPro:IPR000182" /db_xref="InterPro:IPR016181" /db_xref="SubtiList:BG10612" /db_xref="UniProtKB/Swiss-Prot:P39624" /translation="MYTVKENVSKEAIEEFLQSRKLTLDVPYQFSLGLFENSRLQGVL LYEDSLWESKVLQKKVMNVKLLAANSTGQLKRLFEAFYTVRQMDETDFIFVRVPAEDI GAAHVIQQQPSSYFVGSLLKLAMPPSFYDKTPPFFELGPPEPGDTEAICELARDSFTK SRYFQDPHLSRDAANEIFQEWTRNNLNGRAAVNIVAKHNGEVIGYLQGLSRDDECILD LMAVKPGFEGKRIAFHLLANLIEQPETQKHRTVTAGTQLHNVRAIRLYERMGFTAEQS YYYYHIWPGKEAK*" gene complement(3754460..3755329) /gene="spsD" /locus_tag="BSU_37880" /old_locus_tag="BSU37880" CDS complement(3755330..3756499) /gene="spsC" /locus_tag="BSU_37890" /old_locus_tag="BSU37890" /EC_number="2.6.1.-" /function="16.8: Protect" /function="16.13: Shape" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 14602648; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative glutamine-dependent sugar transaminase" /protein_id="NP_391668.1" /db_xref="EnsemblGenomes-Gn:BSU37890" /db_xref="EnsemblGenomes-Tr:CAB15815" /db_xref="GOA:P39623" /db_xref="InterPro:IPR000653" /db_xref="InterPro:IPR015421" /db_xref="InterPro:IPR015422" /db_xref="InterPro:IPR015424" /db_xref="SubtiList:BG10611" /db_xref="UniProtKB/Swiss-Prot:P39623" /translation="MVQKRNHFLPYSLPLIGKEEIQEVTETLESGWLSKGPKVQQFEK EFAAFVGAKHAVAVNSCTAALFLALKAKGIGPGDEVITSPLTFSSTANTIIHTGATPV FADIDENTLNIDPVKLEAAVTPRTKAVVPVHFGGQSCDMDAILAVAQNHGLFVLEDAA HAVYTTYKQRMIGSIGDATAFSFYATKNLATGEGGMLTTDDEELADKIRVLSLHGMSK AAWNRYSSNGSWYYEVESPGYKMNMFDLQAALGLHQLKRLDDMQKRREEIAGRYQTAF QQIPGLITPFVHDDGRHAWHLYVLQVDEKKAGVTRSEMITALKDEYNIGTSVHFIPVH IHPYYQKQFGYKEADFPNAMNYYKRTLSLPLYPSMSDDDVDDVIEAVRDIVKGAD*" gene complement(3755330..3756499) /gene="spsC" /locus_tag="BSU_37890" /old_locus_tag="BSU37890" CDS complement(3756520..3757944) /gene="spsB" /locus_tag="BSU_37900" /old_locus_tag="BSU37900" /function="16.5: Explore" /function="16.8: Protect" /function="16.13: Shape" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 22611084; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative dTDP glycosyl/glycerophosphate transferase or transport" /protein_id="NP_391669.2" /db_xref="EnsemblGenomes-Gn:BSU37900" /db_xref="EnsemblGenomes-Tr:CAB15816" /db_xref="GOA:P39622" /db_xref="InterPro:IPR007554" /db_xref="SubtiList:BG10610" /db_xref="UniProtKB/Swiss-Prot:P39622" /translation="MSAYLSNYWVLYRKYVELFDKLRYKGIPLGLISNFYQYISPELR VMMEEEPELFGSVDQHIDEGQIQPFFEERIQNIVKTNDEPVKGKVILHFDYLRFSNEN YYQFDPEKTAVLARWSLPHYCDLPVISKREIADSCQKGDSKQYLETACSLLAPYDDHP AFGDQAFRDRLFKDIPLFIEAIDTVDALFEQEKISAVIVGTAEDIYSRVLALMCQRKG AVSICLQHGALMGDEAFIPVFTTYQAVFGAYEAEWFIRKGCKPEQILVTGHPRFDQIF NRTPMDMSIFYRKLAFQPTKKIVLIATQPFSEDFYSGVLQGLSDQKQLQIIIKPHPWE IGKNKLDLYHEAAKKHQACRVIKKELELYDLLPYVDAAVTQTSTVGLEAMLFQKPVLI GKSSGNRSYPYYESLGDFMFDQPDELAHTLVEVLRSPDVHQKAEEARLAFIAANYPVA ESTNALFAELKAKTGVDYRREDTE*" gene complement(3756520..3757944) /gene="spsB" /locus_tag="BSU_37900" /old_locus_tag="BSU37900" CDS complement(3757949..3758719) /gene="spsA" /locus_tag="BSU_37910" /old_locus_tag="BSU37910" /function="16.8: Protect" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:10350455, 11042447, 11733986" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10350455, 11042447, 11733986; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="spore coat dTDP-glycosyltransferase" /protein_id="NP_391670.1" /db_xref="EnsemblGenomes-Gn:BSU37910" /db_xref="EnsemblGenomes-Tr:CAB15817" /db_xref="GOA:P39621" /db_xref="InterPro:IPR001173" /db_xref="InterPro:IPR029044" /db_xref="PDB:1H7L" /db_xref="PDB:1H7Q" /db_xref="PDB:1QG8" /db_xref="PDB:1QGQ" /db_xref="PDB:1QGS" /db_xref="SubtiList:BG10609" /db_xref="UniProtKB/Swiss-Prot:P39621" /translation="MPKVSVIMTSYNKSDYVAKSISSILSQTFSDFELFIMDDNSNEE TLNVIRPFLNDNRVRFYQSDISGVKERTEKTRYAALINQAIEMAEGEYITYATDDNIY MPDRLLKMVRELDTHPEKAVIYSASKTYHLNENRDIVKETVRPAAQVTWNAPCAIDHC SVMHRYSVLEKVKEKFGSYWDESPAFYRIGDARFFWRVNHFYPFYPLDEELDLNYITD QSIHFQLFELEKNEFVRNLPPQRNCRELRESLKKLGMG*" gene complement(3757949..3758719) /gene="spsA" /locus_tag="BSU_37910" /old_locus_tag="BSU37910" promotor_-10 complement(3758754..3758773) /Source="Nicolas_upshift_promotors" /id="U2977" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1357 /SigmaFactorBS="atacacaaacttttcgcatattggtttgtatcCCTAGCGCAA cttgagcataagcAACATAAGATAACGATAGTTtcaggtgtgaagttccaagaaggag g" /listShort="spsA, spsB, spsC, spsD, spsE, spsF, spsG, spsI, spsJ, spsK, spsL, S1462, yweA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3758768) /Source="Nicolas_upshifts" /id="U2977" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1357 /SigmaFactorBS="atacacaaacttttcgcatattggtttgtatcCCTAGCGCAA cttgagcataagcAACATAAGATAACGATAGTTtcaggtgtgaagttccaagaaggag g" /listShort="spsA, spsB, spsC, spsD, spsE, spsF, spsG, spsI, spsJ, spsK, spsL, S1462, yweA" /GFF_Attribute="listLong" promotor_-35 complement(3758787..3758796) /Source="Nicolas_upshift_promotors" /id="U2977" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1357 /SigmaFactorBS="atacacaaacttttcgcatattggtttgtatcCCTAGCGCAA cttgagcataagcAACATAAGATAACGATAGTTtcaggtgtgaagttccaagaaggag g" /listShort="spsA, spsB, spsC, spsD, spsE, spsF, spsG, spsI, spsJ, spsK, spsL, S1462, yweA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 3758887..3758892 /Source="Nicolas_upshift_promotors" /id="U2978" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1093 /SigmaFactorBS="cccagagcgaaatctgatcggtccgctgttctttttcAGCAT AatccaagcatcagccTCATAAGGTGAAAGAGATAaaaatcgcaccagcgactaagat c" /listShort="S1463, ywdL" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3758908..3758926 /Source="Nicolas_upshift_promotors" /id="U2978" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1093 /SigmaFactorBS="cccagagcgaaatctgatcggtccgctgttctttttcAGCAT AatccaagcatcagccTCATAAGGTGAAAGAGATAaaaatcgcaccagcgactaagat c" /listShort="S1463, ywdL" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 3758910..3759038 /Source="Nicolas_S_feature" /locus_tag="new_3893312_3893440" /HighExp="S5, S4, S3, S7, B36, S8, S6, B60, T5.0H, G/S" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigEF" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1463" upshifts 3758910 /Source="Nicolas_upshifts" /id="U2978" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1093 /SigmaFactorBS="cccagagcgaaatctgatcggtccgctgttctttttcAGCAT AatccaagcatcagccTCATAAGGTGAAAGAGATAaaaatcgcaccagcgactaagat c" /listShort="S1463, ywdL" /GFF_Attribute="listLong" CDS 3759039..3759584 /gene="gerQ" /locus_tag="BSU_37920" /old_locus_tag="BSU37920" /function="16.8: Protect" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:12644503, 15317760, 16936016, 16936016, 19933362" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12644503, 15317760, 16936016, 16936016, 19933362; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="inner spore coat protein" /protein_id="NP_391671.1" /db_xref="EnsemblGenomes-Gn:BSU37920" /db_xref="EnsemblGenomes-Tr:CAB15818" /db_xref="GOA:P39620" /db_xref="InterPro:IPR014099" /db_xref="SubtiList:BG10608" /db_xref="UniProtKB/Swiss-Prot:P39620" /translation="MKPKKNQYQQMQAFDNMQGYQPQFGANPYPQQGQGSQMQTMGMQ PMMPMQQGQQGQQGQQGFGFPGQQQGGGFQIPSGPTPSGPGQSVPGMLPVEESYIENI LRLNRGKTATIYMTFENSKEWGSKIFRGVIEAAGRDHIIISDPKSGTRYLLLTIYLDY ITFDEEIAYTYPYSMASYSPR*" gene 3759039..3759584 /gene="gerQ" /locus_tag="BSU_37920" /old_locus_tag="BSU37920" downshifts 3759570 /Source="Nicolas_upshifts" /id="D1961" /incds=0 /nref=60 /ntot=77 /MaxReadThrough="1.98659" /MaxDrop="7.96105" /score="16.9179802" /energy="-11.7" /TU="NA" /idTUdmin="U2978" /TUdmin=0 /isTUend="TRUE" CDS complement(3759628..3759999) /gene="ywdK" /locus_tag="BSU_37930" /old_locus_tag="BSU37930" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 15919996, 21810204; Product type m:membrane component" /codon_start=1 /transl_table=11 /product="conserved membrane protein" /protein_id="NP_391672.2" /db_xref="EnsemblGenomes-Gn:BSU37930" /db_xref="EnsemblGenomes-Tr:CAB15819" /db_xref="GOA:P39619" /db_xref="InterPro:IPR006696" /db_xref="SubtiList:BG10607" /db_xref="UniProtKB/Swiss-Prot:P39619" /translation="MKVFIILGAINALLAVGLGAFGAHGLEGKIPDKYLQVWHTGVQY HMYHALGLFVVAFLADKLSGIGSVTTAGWLMFAGIVLFSGSLYILSVTQISILGAITP LGGVAFIISWIMIVVAAVKYL*" gene complement(3759628..3759999) /gene="ywdK" /locus_tag="BSU_37930" /old_locus_tag="BSU37930" downshifts complement(3759646) /Source="Nicolas_upshifts" /id="D1962" /incds=0 /nref=134 /ntot=227 /MaxReadThrough="3.65585" /MaxDrop="4.84049" /score="15.105437" /energy="-11.7" /TU="NA" /idTUdmin="U2979" /TUdmin=0 /isTUend="TRUE" CDS complement(3760061..3761383) /gene="ywdJ" /locus_tag="BSU_37940" /old_locus_tag="BSU37940" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative purine/pyrimidine permease" /protein_id="NP_391673.2" /db_xref="EnsemblGenomes-Gn:BSU37940" /db_xref="EnsemblGenomes-Tr:CAB15820" /db_xref="GOA:P39618" /db_xref="InterPro:IPR006042" /db_xref="InterPro:IPR006043" /db_xref="SubtiList:BG10606" /db_xref="UniProtKB/Swiss-Prot:P39618" /translation="MKLVLGALQWTAFIIAAAIVVPVAVAQSFHLDHSDSARLIQSTF FVLGIAAVIQCLKGHRLPINESPAGLWWGVYTIYAGLTGTVFATYGDTLRGLQGALLV SAVCFFLLSVFKVIDRLAKLFTPVVTGVYLLLLVMQLSQPIIKGILGIGYRQDGVDGL VFGLALVVIAAAFIMTNSNIMFFKQYSILLALFGGWVLFAAAGAAKPIEMPDRLFQLP SLFPFGTPLFNSGLIITSIFITILLIVNMLASMKVVDIAMKKFSKQPDGKHHERHAGF AASFSHLLSGLTGAIAPVPISGAAGFIETTKMPSKKPFMLGSILVIVISVIPFFMNTF ASLPSPVGFAVNFVVFSAMGGLAFAEFDSYEKEESKRVRSIIGISLLTGVGIMFVPET ALKGLHPVFISLLSNGLVLGTLAAIAADQFQLWRRRKSDNLVSTENKH*" gene complement(3760061..3761383) /gene="ywdJ" /locus_tag="BSU_37940" /old_locus_tag="BSU37940" CDS complement(3761403..3761720) /gene="ywdI" /locus_tag="BSU_37950" /old_locus_tag="BSU37950" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_391674.3" /db_xref="EnsemblGenomes-Gn:BSU37950" /db_xref="EnsemblGenomes-Tr:CAB15821" /db_xref="InterPro:IPR035218" /db_xref="SubtiList:BG10605" /db_xref="UniProtKB/Swiss-Prot:P39617" /translation="MNIHISALIQKMEEELKKAKTAERDEELKRYVAVVRSLCDVVLD QPENASAPRIQPSVTPSPAAPPSTDQLMMEKMMGSAGLNKYRKQEKEKQEEDGNGESL FDF*" gene complement(3761403..3761720) /gene="ywdI" /locus_tag="BSU_37950" /old_locus_tag="BSU37950" promotor_-10 complement(3761749..3761768) /Source="Nicolas_upshift_promotors" /id="U2979" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.517482517482518" /psig=1 /xcortree=1928 /SigmaFactorBS="gcaaggtttgtcagaaaaaataacaaactcatATCTGCGttt tcagcaggaaTTTGATAAAATGCAGGAAGAcaacatttatttttttggagggtgcttc a" /listShort="ywdI, ywdJ, ywdK" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3761760) /Source="Nicolas_upshifts" /id="U2979" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.517482517482518" /psig=1 /xcortree=1928 /SigmaFactorBS="gcaaggtttgtcagaaaaaataacaaactcatATCTGCGttt tcagcaggaaTTTGATAAAATGCAGGAAGAcaacatttatttttttggagggtgcttc a" /listShort="ywdI, ywdJ, ywdK" /GFF_Attribute="listLong" promotor_-35 complement(3761782..3761788) /Source="Nicolas_upshift_promotors" /id="U2979" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.517482517482518" /psig=1 /xcortree=1928 /SigmaFactorBS="gcaaggtttgtcagaaaaaataacaaactcatATCTGCGttt tcagcaggaaTTTGATAAAATGCAGGAAGAcaacatttatttttttggagggtgcttc a" /listShort="ywdI, ywdJ, ywdK" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 3761823..3761830 /Source="Nicolas_upshift_promotors" /id="U2980" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.52947052947053" /psig="0.988011988011988" /xcortree=1868 /SigmaFactorBS="atgagtttgttattttttctgacaaaccttgcgcGATTGACA agcagaagagattttTCACATAATAAATCACCATAccttacaaaaaggagaaacggaa t" /listShort="ywdH" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3761846..3761865 /Source="Nicolas_upshift_promotors" /id="U2980" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.52947052947053" /psig="0.988011988011988" /xcortree=1868 /SigmaFactorBS="atgagtttgttattttttctgacaaaccttgcgcGATTGACA agcagaagagattttTCACATAATAAATCACCATAccttacaaaaaggagaaacggaa t" /listShort="ywdH" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3761849 /Source="Nicolas_upshifts" /id="U2980" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.52947052947053" /psig="0.988011988011988" /xcortree=1868 /SigmaFactorBS="atgagtttgttattttttctgacaaaccttgcgcGATTGACA agcagaagagattttTCACATAATAAATCACCATAccttacaaaaaggagaaacggaa t" /listShort="ywdH" /GFF_Attribute="listLong" CDS 3761888..3763258 /gene="ywdH" /locus_tag="BSU_37960" /old_locus_tag="BSU37960" /EC_number="1.2.1.-" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative aldehyde dehydrogenase" /protein_id="NP_391675.2" /db_xref="EnsemblGenomes-Gn:BSU37960" /db_xref="EnsemblGenomes-Tr:CAB15822" /db_xref="GOA:P39616" /db_xref="InterPro:IPR012394" /db_xref="InterPro:IPR015590" /db_xref="InterPro:IPR016160" /db_xref="InterPro:IPR016161" /db_xref="InterPro:IPR016162" /db_xref="InterPro:IPR029510" /db_xref="SubtiList:BG10604" /db_xref="UniProtKB/Swiss-Prot:P39616" /translation="MNSIPSIISKHKAYFAAGHTRPLESRLNILRKLKQAVRTHEADL IAALYQDLHKSEQEAYSTEIGIVLEEISFVMKRLRKWSKPKRVKTPLTHLGSKSIIIP EPYGTVLVIAPWNYPLQLALSPLIGAIAAGNTVVLKPSEYTPAVSAILSKLISSVFPT DYVAMAEGGPDVSTALLQQPFDYIFFTGSVAVGKIVMEAAAKQLIPVTLELGGKSPCI VHKDADIQLAAKRIVFGKFTNAGQTCIAPDYLFVHEDIKTKLTEEMKRAIREFYGPQP ERNPQYGKIVSERHYQRLLSFLNDGIPLTGGQSDPNHHKIAPTILEQVRDDSPVMQEE IFGPILPLFTYRNIGEVIEKVQSRPKPLALYLFTTNKEIERAVLGNLSFGGGCVNDTL MHVATPYLPFGGVGESGIGSYHGFDSFNTFTHKKSVVKQTNRFDFAFRYPSSKNGLRM IRKILK*" gene 3761888..3763258 /gene="ywdH" /locus_tag="BSU_37960" /old_locus_tag="BSU37960" CDS complement(3763283..3763960) /gene="ung" /locus_tag="BSU_37970" /old_locus_tag="BSU37970" /EC_number="3.2.2.27" /function="16.8: Protect" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:1902430, 9776748, 10080896, 21542855, 22056936" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1902430, 9776748, 10080896, 21542855, 22056936; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="uracil-DNA glycosylase" /protein_id="NP_391676.1" /db_xref="EnsemblGenomes-Gn:BSU37970" /db_xref="EnsemblGenomes-Tr:CAB15823" /db_xref="GOA:P39615" /db_xref="InterPro:IPR002043" /db_xref="InterPro:IPR005122" /db_xref="InterPro:IPR018085" /db_xref="InterPro:IPR036895" /db_xref="PDB:3ZOQ" /db_xref="PDB:3ZOR" /db_xref="SubtiList:BG10603" /db_xref="UniProtKB/Swiss-Prot:P39615" /translation="MKQLLQDSWWNQLKEEFEKPYYQELREMLKREYAEQTIYPDSRD IFNALHYTSYDDVKVVILGQDPYHGPGQAQGLSFSVKPGVKQPPSLKNIFLELQQDIG CSIPNHGSLVSWAKQGVLLLNTVLTVRRGQANSHKGKGWERLTDRIIDVLSERERPVI FILWGRHAQMKKERIDTSKHFIIESTHPSPFSARNGFFGSRPFSRANAYLEKMGEAPI DWCIKDL*" gene complement(3763283..3763960) /gene="ung" /locus_tag="BSU_37970" /old_locus_tag="BSU37970" downshifts complement(3763297) /Source="Nicolas_upshifts" /id="D1963" /incds=0 /nref=66 /ntot=224 /MaxReadThrough="2.25259" /MaxDrop="4.72154" /score="26.8023311" /energy="-9.1" /TU="NA" /idTUdmin="U2982" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(3763787..3763806) /Source="Nicolas_upshift_promotors" /id="U2981" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.425574425574426" /psig="0.837162837162837" /xcortree=1736 /SigmaFactorBS="acgcggagcaaacgatttatccggacagccgggataTTTTCA acgcgctgcattataCATCATATGATGATGTCAAGgtcgtcattttgggtcaagatcc g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3763803) /Source="Nicolas_upshifts" /id="U2981" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.425574425574426" /psig="0.837162837162837" /xcortree=1736 /SigmaFactorBS="acgcggagcaaacgatttatccggacagccgggataTTTTCA acgcgctgcattataCATCATATGATGATGTCAAGgtcgtcattttgggtcaagatcc g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(3763822..3763827) /Source="Nicolas_upshift_promotors" /id="U2981" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.425574425574426" /psig="0.837162837162837" /xcortree=1736 /SigmaFactorBS="acgcggagcaaacgatttatccggacagccgggataTTTTCA acgcgctgcattataCATCATATGATGATGTCAAGgtcgtcattttgggtcaagatcc g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3763974..3764780) /gene="ywdF" /locus_tag="BSU_37980" /old_locus_tag="BSU37980" /EC_number="2.4.-.-" /function="16.13: Shape" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 9334165; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative glycosyltransferase" /protein_id="NP_391677.1" /db_xref="EnsemblGenomes-Gn:BSU37980" /db_xref="EnsemblGenomes-Tr:CAB15824" /db_xref="GOA:P39614" /db_xref="InterPro:IPR001173" /db_xref="InterPro:IPR029044" /db_xref="SubtiList:BG10602" /db_xref="UniProtKB/Swiss-Prot:P39614" /translation="MKISIVIVTYNRIPALCELLESISRQTLMPYEIIIVNDAGESVV PVKALYPELPIAVINLEKNSGHVAARNAGVKEASGDCIMLCDDDDFFTPGHIEKMAKE IETADFVHSDAEIVSFEEKNGTRYPVSRKLFAYTADYEDMRVFSTYVPSGSMYRRFLH DEIGYFDADVHNYWDWDFYLRAAKDYRVKRVPCASVIYAFSDAGDNQSADLGAKRKQY LDRLSEKHGLGELPTKNFAVLLEEPEMKRREAKSEMVWDGEPVYSRLHRS*" gene complement(3763974..3764780) /gene="ywdF" /locus_tag="BSU_37980" /old_locus_tag="BSU37980" promotor_-10 complement(3764273..3764291) /Source="Nicolas_upshift_promotors" /id="U2982" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=139 /SigmaFactorBS="tttctacatacgtgccgtcgggcagcatgtacagaCGTTTTC tgcatgatgaaatcGGGTATTTCGATGCTGATGtgcacaattactgggactgggattt t" /listShort="ung" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3764287) /Source="Nicolas_upshifts" /id="U2982" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=139 /SigmaFactorBS="tttctacatacgtgccgtcgggcagcatgtacagaCGTTTTC tgcatgatgaaatcGGGTATTTCGATGCTGATGtgcacaattactgggactgggattt t" /listShort="ung" /GFF_Attribute="listLong" promotor_-35 complement(3764306..3764312) /Source="Nicolas_upshift_promotors" /id="U2982" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=139 /SigmaFactorBS="tttctacatacgtgccgtcgggcagcatgtacagaCGTTTTC tgcatgatgaaatcGGGTATTTCGATGCTGATGtgcacaattactgggactgggattt t" /listShort="ung" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(3764809..3764828) /Source="Nicolas_upshift_promotors" /id="U2983" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.612387612387612" /psig="0.996003996003996" /xcortree=2559 /SigmaFactorBS="ttgtagtatgccgtttcagtaggaTATTCCCActgatctccc gtccaATATATGTTTTAATAGTACAtgactatgaaaatgagaaggagagcatcatgaa g" /listShort="ywdF, ung" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3764815) /Source="Nicolas_upshifts" /id="U2983" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.612387612387612" /psig="0.996003996003996" /xcortree=2559 /SigmaFactorBS="ttgtagtatgccgtttcagtaggaTATTCCCActgatctccc gtccaATATATGTTTTAATAGTACAtgactatgaaaatgagaaggagagcatcatgaa g" /listShort="ywdF, ung" /GFF_Attribute="listLong" promotor_-35 complement(3764844..3764851) /Source="Nicolas_upshift_promotors" /id="U2983" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.612387612387612" /psig="0.996003996003996" /xcortree=2559 /SigmaFactorBS="ttgtagtatgccgtttcagtaggaTATTCCCActgatctccc gtccaATATATGTTTTAATAGTACAtgactatgaaaatgagaaggagagcatcatgaa g" /listShort="ywdF, ung" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3764870..3765403) /gene="ywdE" /locus_tag="BSU_37990" /old_locus_tag="BSU37990" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative integral inner membrane protein of unknown function" /protein_id="NP_391678.1" /db_xref="EnsemblGenomes-Gn:BSU37990" /db_xref="EnsemblGenomes-Tr:CAB15825" /db_xref="GOA:P39613" /db_xref="SubtiList:BG10601" /db_xref="UniProtKB/Swiss-Prot:P39613" /translation="MRISSCLYGFVAHGAVFLFTGGCMLLAMAASLPFVFLLDRLPDV VFTAGAILTLLCSYAYVWFWAVRFAYNQKMRLFEVQLGSFVLLALMISLFLLDGSSMK DIMMNWDDAGCAFVPPAFTFLCLSYALVLLPVYQSKLWRLILPNGVRMKDIFHVFGDL MLIMVLLIGATLLFLSL*" gene complement(3764870..3765403) /gene="ywdE" /locus_tag="BSU_37990" /old_locus_tag="BSU37990" CDS complement(3765451..3766086) /gene="ywdD" /locus_tag="BSU_38000" /old_locus_tag="BSU38000" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative integral inner membrane protein of unknown function" /protein_id="NP_391679.2" /db_xref="EnsemblGenomes-Gn:BSU38000" /db_xref="EnsemblGenomes-Tr:CAB15826" /db_xref="GOA:P39612" /db_xref="SubtiList:BG10600" /db_xref="UniProtKB/Swiss-Prot:P39612" /translation="MDKETYVSEIKSGLKGLPEGEAMIEEIESHIEHHLFRSFQEGKS EEEAMQTLLQAFGTPTDIVSSFKKIQPVTFRAFLMFHLFCNSALFAVGIAITIMHVWL ESPFVQAVWKGISVSVWLILAAYMIYWVLIGYQGVKEFGKRGEKLVLHTILISMVPNV IFMLVFLFNVIPAALFQSLLTPWFVGTCAFATLLFPLFGRMGCYIGRRQLV*" gene complement(3765451..3766086) /gene="ywdD" /locus_tag="BSU_38000" /old_locus_tag="BSU38000" CDS complement(3766079..3766417) /gene="ywzG" /locus_tag="BSU_38018" /old_locus_tag="BSU38018" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative transcriptional regulator, PadR family" /protein_id="YP_003097793.1" /db_xref="EnsemblGenomes-Gn:BSU38018" /db_xref="EnsemblGenomes-Tr:CAX52706" /db_xref="GOA:C0H3S6" /db_xref="InterPro:IPR005149" /db_xref="InterPro:IPR011991" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="UniProtKB/Swiss-Prot:C0H3S6" /translation="MLNRELVKGSTVILVLTLLNERPMYGYELVKEMGSRSGNELQMK EGTLYPSLHKLERQGYISSYWEKQEKGPDRKYYRITDEGKEVLAERTKEWSVFSAMMD RILKWSGQNG*" gene complement(3766079..3766417) /gene="ywzG" /locus_tag="BSU_38018" /old_locus_tag="BSU38018" promotor_-10 complement(3766439..3766458) /Source="Nicolas_upshift_promotors" /id="U2984" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.468531468531469" /psig="0.998001998001998" /xcortree=2997 /SigmaFactorBS="gtatcacaatatagaagatctataggaatcATTTGACAatct caacgggcttTCGTAAAATGCTACATAAGAaaactaggtaggggttttgagatgttaa a" /listShort="ywzG, ywdD, ywdE" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3766450) /Source="Nicolas_upshifts" /id="U2984" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.468531468531469" /psig="0.998001998001998" /xcortree=2997 /SigmaFactorBS="gtatcacaatatagaagatctataggaatcATTTGACAatct caacgggcttTCGTAAAATGCTACATAAGAaaactaggtaggggttttgagatgttaa a" /listShort="ywzG, ywdD, ywdE" /GFF_Attribute="listLong" promotor_-35 complement(3766473..3766480) /Source="Nicolas_upshift_promotors" /id="U2984" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.468531468531469" /psig="0.998001998001998" /xcortree=2997 /SigmaFactorBS="gtatcacaatatagaagatctataggaatcATTTGACAatct caacgggcttTCGTAAAATGCTACATAAGAaaactaggtaggggttttgagatgttaa a" /listShort="ywzG, ywdD, ywdE" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 3766501..3766504 /Source="Nicolas_upshift_promotors" /id="U2985" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.926073926073926" /psig=1 /xcortree=2350 /SigmaFactorBS="aagcccgttgagattgtcaaatgattcctatagatcttctat ATTGtgatacagagaaaaTCTAACTATAATGAAAGACAaaacatgatggaggttcaag a" /listShort="pdxK" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3766519..3766538 /Source="Nicolas_upshift_promotors" /id="U2985" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.926073926073926" /psig=1 /xcortree=2350 /SigmaFactorBS="aagcccgttgagattgtcaaatgattcctatagatcttctat ATTGtgatacagagaaaaTCTAACTATAATGAAAGACAaaacatgatggaggttcaag a" /listShort="pdxK" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3766519 /Source="Nicolas_upshifts" /id="U2985" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.926073926073926" /psig=1 /xcortree=2350 /SigmaFactorBS="aagcccgttgagattgtcaaatgattcctatagatcttctat ATTGtgatacagagaaaaTCTAACTATAATGAAAGACAaaacatgatggaggttcaag a" /listShort="pdxK" /GFF_Attribute="listLong" CDS 3766561..3767376 /gene="pdxK" /locus_tag="BSU_38020" /old_locus_tag="BSU38020" /EC_number="2.7.1.35" /function="16.11: Scavenge (Catabolism)" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:10939241, 14973012, 17012797" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10939241, 14973012, 17012797; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="pyridoxine, pyridoxal, and pyridoxamine kinase" /protein_id="NP_391681.1" /db_xref="EnsemblGenomes-Gn:BSU38020" /db_xref="EnsemblGenomes-Tr:CAB15828" /db_xref="GOA:P39610" /db_xref="InterPro:IPR004399" /db_xref="InterPro:IPR013749" /db_xref="InterPro:IPR029056" /db_xref="PDB:2I5B" /db_xref="SubtiList:BG10598" /db_xref="UniProtKB/Swiss-Prot:P39610" /translation="MSMHKALTIAGSDSSGGAGIQADLKTFQEKNVYGMTALTVIVAM DPNNSWNHQVFPIDTDTIRAQLATITDGIGVDAMKTGMLPTVDIIELAAKTIKEKQLK NVVIDPVMVCKGANEVLYPEHAQALREQLAPLATVITPNLFEASQLSGMDELKTVDDM IEAAKKIHALGAQYVVITGGGKLKHEKAVDVLYDGETAEVLESEMIDTPYTHGAGCTF SAAVTAELAKGAEVKEAIYAAKEFITAAIKESFPLNQYVGPTKHSALRLNQQS*" gene 3766561..3767376 /gene="pdxK" /locus_tag="BSU_38020" /old_locus_tag="BSU38020" downshifts 3767355 /Source="Nicolas_upshifts" /id="D1964" /incds=0 /nref=185 /ntot=251 /MaxReadThrough="2.56759" /MaxDrop="5.39956" /score="22.0760698" /energy="-18.1" /TU="NA" /idTUdmin="U2985" /TUdmin=0 /isTUend="TRUE" downshifts complement(3767431) /Source="Nicolas_upshifts" /id="D1965" /incds=0 /nref=20 /ntot=111 /MaxReadThrough="0.56945" /MaxDrop="6.81686" /score="39.7901804" /energy="-16.8" /TU="NA" /idTUdmin="U2987" /TUdmin=0 /isTUend="TRUE" CDS complement(3767466..3767714) /gene="ywdA" /locus_tag="BSU_38030" /old_locus_tag="BSU38030" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_391682.1" /db_xref="EnsemblGenomes-Gn:BSU38030" /db_xref="EnsemblGenomes-Tr:CAB15829" /db_xref="SubtiList:BG10597" /db_xref="UniProtKB/Swiss-Prot:P39609" /translation="MNIHEQKITPECLEKAANQVEDKREEYKDVLLQLKKMLGGTTPH SETAEILTRAYEQMKEYALFVQSIETFLRKSANNLKIK*" gene complement(3767466..3767714) /gene="ywdA" /locus_tag="BSU_38030" /old_locus_tag="BSU38030" downshifts complement(3767486) /Source="Nicolas_upshifts" /id="D1966" /incds=0 /nref=6 /ntot=123 /MaxReadThrough="6.75845" /MaxDrop="3.89221" /score="22.6408081" /energy="-10.8" /TU="U2987,U2988" /idTUdmin="U2986" /TUdmin=11 /isTUend="TRUE" upshifts complement(3767732) /Source="Nicolas_upshifts" /id="U2986" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.211788211788212" /psig="0.230769230769231" /xcortree=577 /SigmaFactorBS="tcttatgtgaaatctgagccatctgtgctattcttcaacgat aaCCTACTAtttttttctgtaaaaggagttgttttcttgaatatacatgaacagaaga t" /listShort="ywdA" /GFF_Attribute="listLong" S_feature complement(3767734..3767807) /Source="Nicolas_S_feature" /locus_tag="new_3902136_3902209_c" /HighExp="G150, Mt0, Diami, Lbexp, dia0, dia5, T0.30H, Oxctl, Etha, dia15" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA, SigA" /TUshortPSig="0.536, 0.743, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S1464" misc_feature complement(3767742..3767748) /Source="Nicolas_upshift_promotors" /id="U2986" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.211788211788212" /psig="0.230769230769231" /xcortree=577 /SigmaFactorBS="tcttatgtgaaatctgagccatctgtgctattcttcaacgat aaCCTACTAtttttttctgtaaaaggagttgttttcttgaatatacatgaacagaaga t" /listShort="ywdA" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" CDS complement(3767808..3769247) /gene="sacA" /locus_tag="BSU_38040" /old_locus_tag="BSU38040" /EC_number="3.2.1.26" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2b: Function from indirect experimental evidences (e.g. phenotypes); PubMedId: 3100393; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="sucrose-6-phosphate hydrolase" /protein_id="NP_391683.2" /db_xref="EnsemblGenomes-Gn:BSU38040" /db_xref="EnsemblGenomes-Tr:CAB15830" /db_xref="GOA:P07819" /db_xref="InterPro:IPR001362" /db_xref="InterPro:IPR006232" /db_xref="InterPro:IPR013148" /db_xref="InterPro:IPR013189" /db_xref="InterPro:IPR013320" /db_xref="InterPro:IPR018053" /db_xref="InterPro:IPR023296" /db_xref="SubtiList:BG10596" /db_xref="UniProtKB/Swiss-Prot:P07819" /translation="MTAHDQELRRRAYEEVEKKEPIANSDPHRQHFHIMPPVGLLNDP NGVIYWKGSYHVFFQWQPFQTGHGAKFWGHYTTQDVVNWKREEIALAPSDWFDKNGCY SGSAVTKDDRLYLFYTGNVRDQDGNRETYQCLAVSDDGLSFEKKGVVARLPEGYTAHF RDPKVWEHEGTWYMVIGAQTENLKGQAVLFASDNLTEWRFLGPITGAGFNGLDDFGYM WECPDLFSLQGSDVLIVSPQGLEADGFRYQNVYQSGYFVGRLDYNKPELKHGEFTELD QGFDFYAPQTLEDDQGRRILFAWMAVPDQDEGSHPTIDCHWIHCMTLPRQLTLSGQKL IQQPLPELKAMRRNEKKIHINMHGSSGALPVEKPERTEILLEDIHTESGFSISIRGTA TFSFHKDEGIVTLERKSFDGKRTEARHCRIKDLHTVHMFLDASSVEIFINNGEEVLSA RYFPFPGNHEVTASATGKSEMNVGIWTLM*" gene complement(3767808..3769247) /gene="sacA" /locus_tag="BSU_38040" /old_locus_tag="BSU38040" CDS complement(3769244..3770629) /gene="sacP" /locus_tag="BSU_38050" /old_locus_tag="BSU38050" /EC_number="2.7.1.211" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:1577686, 3122206, 15849754, 16850406" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1577686, 3122206, 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="phosphotransferase system (PTS) sucrose-specificenzyme IIBC component" /protein_id="NP_391684.3" /db_xref="EnsemblGenomes-Gn:BSU38050" /db_xref="EnsemblGenomes-Tr:CAB15831" /db_xref="GOA:P05306" /db_xref="InterPro:IPR001996" /db_xref="InterPro:IPR003352" /db_xref="InterPro:IPR004719" /db_xref="InterPro:IPR010973" /db_xref="InterPro:IPR013013" /db_xref="InterPro:IPR018113" /db_xref="InterPro:IPR036878" /db_xref="SubtiList:BG10595" /db_xref="UniProtKB/Swiss-Prot:P05306" /translation="MDYKETAKRLIELLGGKENIISAAHCATRLRLVMKDESKIDQAQ VEELDGVKGAFSSSGQYQIIFGTGLVNKVFDAFSKEADIEREEHVNHQDAAKEKLNPA ARFAKTLSNIFVPIIPAIVASGLLMGLLGMINAFHWMSKDSALLQLLDMFSSAAFIFL PILIGVSASKEFGSNPYLGAVIGGIMIHPNLLNPWGLAEATPDYMHLFGFDIALLGYQ GTVIPVLLAVYVMSKVEKWTRKVVPHAVDLLVTPFVTVIVTGFVAFIAIGPLGRALGS GITVALTYVYDHAGFVAGLIFGGTYSLIVLTGVHHSFHAIEAGLIADIGKNYLLPIWS MANVAQGGAGLAVFFMAKKAKTKEIALPAAFSAFLGITEPVIFGVNLRYRKPFIAAMI GGALGGAYVVFTHVAANAYGLTGIPMIAIAAPFGFSNLIHYLIGMAIAAVSAFIAAFV MKINEDEERKK*" gene complement(3769244..3770629) /gene="sacP" /locus_tag="BSU_38050" /old_locus_tag="BSU38050" misc_feature complement(3770648..3770657) /Source="Nicolas_upshift_promotors" /id="U2987" /multdbtbs="-" /comp="M21" /sig="SigA" /pcomp="0.258741258741259" /psig="0.536463536463537" /xcortree=1560 /SigmaFactorBS="ctaaaatttgcgtaaatgaaaaaggatcgctgtgtcctttat tcgttggcgaattttaggtctttTTTGTTTAAAtaaaagggggagaaatagatggatt a" /listShort="sacP, sacA, S1464, ywdA" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(3770662) /Source="Nicolas_upshifts" /id="U2987" /multdbtbs="-" /comp="M21" /sig="SigA" /pcomp="0.258741258741259" /psig="0.536463536463537" /xcortree=1560 /SigmaFactorBS="ctaaaatttgcgtaaatgaaaaaggatcgctgtgtcctttat tcgttggcgaattttaggtctttTTTGTTTAAAtaaaagggggagaaatagatggatt a" /listShort="sacP, sacA, S1464, ywdA" /GFF_Attribute="listLong" S_feature complement(3770664..3770728) /Source="Nicolas_S_feature" /locus_tag="new_3905066_3905130_c" /HighExp="Diami, G150, dia5, Mt0, M9-stat, Lbtran, Gly, dia0, Oxctl, Lbexp" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="0.743, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S1465" promotor_-10 complement(3770707..3770724) /Source="Nicolas_upshift_promotors" /id="U2988" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.538461538461538" /psig="0.743256743256743" /xcortree=1561 /SigmaFactorBS="gatttatgatgaaagcgtattcttaatctgaataagcgggaT TGTGACTggtaaagcaggcaagACCTAAAATTTGCGTAAAtgaaaaaggatcgctgtg t" /listShort="S1465, sacP, sacA, S1464, ywdA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3770728) /Source="Nicolas_upshifts" /id="U2988" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.538461538461538" /psig="0.743256743256743" /xcortree=1561 /SigmaFactorBS="gatttatgatgaaagcgtattcttaatctgaataagcgggaT TGTGACTggtaaagcaggcaagACCTAAAATTTGCGTAAAtgaaaaaggatcgctgtg t" /listShort="S1465, sacP, sacA, S1464, ywdA" /GFF_Attribute="listLong" promotor_-35 complement(3770740..3770747) /Source="Nicolas_upshift_promotors" /id="U2988" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.538461538461538" /psig="0.743256743256743" /xcortree=1561 /SigmaFactorBS="gatttatgatgaaagcgtattcttaatctgaataagcgggaT TGTGACTggtaaagcaggcaagACCTAAAATTTGCGTAAAtgaaaaaggatcgctgtg t" /listShort="S1465, sacP, sacA, S1464, ywdA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(3770770..3770789) /Source="Nicolas_upshift_promotors" /id="U2989" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.98001998001998" /psig=1 /xcortree=1544 /SigmaFactorBS="ttgtctacatgttatatcaaactatttaactaaaaaaaTAGT TGACgaaaacgctatcaTGATTTATGATGAAAGCGTAttcttaatctgaataagcggg a" /listShort="S1465, sacP, sacA, S1464, ywdA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3770788) /Source="Nicolas_upshifts" /id="U2989" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.98001998001998" /psig=1 /xcortree=1544 /SigmaFactorBS="ttgtctacatgttatatcaaactatttaactaaaaaaaTAGT TGACgaaaacgctatcaTGATTTATGATGAAAGCGTAttcttaatctgaataagcggg a" /listShort="S1465, sacP, sacA, S1464, ywdA" /GFF_Attribute="listLong" promotor_-35 complement(3770803..3770810) /Source="Nicolas_upshift_promotors" /id="U2989" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.98001998001998" /psig=1 /xcortree=1544 /SigmaFactorBS="ttgtctacatgttatatcaaactatttaactaaaaaaaTAGT TGACgaaaacgctatcaTGATTTATGATGAAAGCGTAttcttaatctgaataagcggg a" /listShort="S1465, sacP, sacA, S1464, ywdA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 3770869..3770872 /Source="Nicolas_upshift_promotors" /id="U2990" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.676323676323676" /psig="0.997002997002997" /xcortree=1600 /SigmaFactorBS="gttaaatagtttgatataacatgtagacaaaaattcgtaaaa attaattgTGAAatacttcacaatatCGTGCTATACTATGCTCAATcatgaaagaaag c" /listShort="ywcJ, S1466" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 3770879 /Source="Nicolas_upshifts" /id="U2990" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.676323676323676" /psig="0.997002997002997" /xcortree=1600 /SigmaFactorBS="gttaaatagtttgatataacatgtagacaaaaattcgtaaaa attaattgTGAAatacttcacaatatCGTGCTATACTATGCTCAATcatgaaagaaag c" /listShort="ywcJ, S1466" /GFF_Attribute="listLong" promotor_-10 3770887..3770906 /Source="Nicolas_upshift_promotors" /id="U2990" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.676323676323676" /psig="0.997002997002997" /xcortree=1600 /SigmaFactorBS="gttaaatagtttgatataacatgtagacaaaaattcgtaaaa attaattgTGAAatacttcacaatatCGTGCTATACTATGCTCAATcatgaaagaaag c" /listShort="ywcJ, S1466" /GFF_Attribute="listLong" /label="promotor_-10" CDS 3770931..3771701 /gene="nirC" /locus_tag="BSU_38060" /old_locus_tag="BSU38060" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 15849754, 16207915, 16428414, 16850406, 18691156; Product type t : transporter" /codon_start=1 /transl_table=11 /product="nitrite transporter" /protein_id="NP_391685.1" /db_xref="EnsemblGenomes-Gn:BSU38060" /db_xref="EnsemblGenomes-Tr:CAB15832" /db_xref="GOA:P39608" /db_xref="InterPro:IPR000292" /db_xref="InterPro:IPR023271" /db_xref="InterPro:IPR024002" /db_xref="SubtiList:BG10594" /db_xref="UniProtKB/Swiss-Prot:P39608" /translation="METQALQKVEQYALKKQNIFASSKIRYVLRSILASIFIGFGITA ASKTGSYFFMADSPFAFPAAAVTFGAAILMIAYGGGDLFTGNTFYFTYTALRKKISWR DTLYLWMSSYAGNLIGAILFAILISATGLFEEPSVHSFLIHLAEHKMEPPASELFFRG MLCNWLVCLAFFIPMSLKGEGAKLFTMMLFVFCFFISGFEHSIANMCTFAISLLIEHP DTVTLMGAVRNLIPVTLGNLTAGIVMMGWMYYTLNPDQ*" gene 3770931..3771701 /gene="nirC" /locus_tag="BSU_38060" /old_locus_tag="BSU38060" S_feature 3771702..3772769 /Source="Nicolas_S_feature" /locus_tag="new_3906104_3907171" /HighExp="S0, ferm, M0t45, Lbexp, Mal, dia0, M/G, UNK1, M40t45, BI" /AntisenseName="sacT" /AntisenseCor="-0.34218080984654098" /AntisenseRegPval="-8.1" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.997" /TUlongSig="NA" /TUlongPSig="NA" /label="S1466" CDS complement(3771740..3772570) /gene="sacT" /locus_tag="BSU_38070" /old_locus_tag="BSU38070" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:1577686, 2163394, 8535520, 8702561, 19202299, 21278164" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1577686, 2163394, 8535520, 8702561, 19202299, 21278164; Product type r : regulator" /codon_start=1 /transl_table=11 /product="transcriptional antiterminator of sacAP expression" /protein_id="NP_391686.1" /db_xref="EnsemblGenomes-Gn:BSU38070" /db_xref="EnsemblGenomes-Tr:CAB15833" /db_xref="GOA:P26212" /db_xref="InterPro:IPR001550" /db_xref="InterPro:IPR004341" /db_xref="InterPro:IPR011608" /db_xref="InterPro:IPR036634" /db_xref="InterPro:IPR036650" /db_xref="SubtiList:BG10593" /db_xref="UniProtKB/Swiss-Prot:P26212" /translation="MKIYKVLNNNAALIKEDDQEKIVMGPGIAFQKKKNDLIPMNKVE KIFVVRDENEKFKQILQTLPEEHIEIAEDIISYAEGELAAPLSDHIHIALSDHLSFAI ERIQNGLLVQNKLLHEIKALYKKEYEIGLWAIGHVKETLGVSLPEDEAGYIALHIHTA KMDAESMYSALKHTTMIKEMIEKIKQYFNRKVDENSISYQRLVTHLRYAVSRLESNEA LHRMDEEMLYFIQKKYSFAYQCALELAEFLKNEYQLHLPESEAGYITLHVQRLQDLSE *" gene complement(3771740..3772570) /gene="sacT" /locus_tag="BSU_38070" /old_locus_tag="BSU38070" downshifts complement(3771741) /Source="Nicolas_upshifts" /id="D1967" /incds=0 /nref=49 /ntot=139 /MaxReadThrough="3.34691" /MaxDrop="4.9787" /score="11.2756812" /energy="-8.1" /TU="U2992" /idTUdmin="U2991" /TUdmin="-1" /isTUend="TRUE" promotor_-10 complement(3772596..3772615) /Source="Nicolas_upshift_promotors" /id="U2991" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.72027972027972" /psig="0.943056943056943" /xcortree=452 /SigmaFactorBS="caaagcaggagagagcgggcccgcaTCTTTACAtggcggtca aaaggAGGTAAAATCCCAGTCAAAAgcaaattggcgggagagataacctcttgaaaat c" /listShort="sacT" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3772602) /Source="Nicolas_upshifts" /id="U2991" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.72027972027972" /psig="0.943056943056943" /xcortree=452 /SigmaFactorBS="caaagcaggagagagcgggcccgcaTCTTTACAtggcggtca aaaggAGGTAAAATCCCAGTCAAAAgcaaattggcgggagagataacctcttgaaaat c" /listShort="sacT" /GFF_Attribute="listLong" CDS complement(3772610..3772912) /gene="ywcI" /locus_tag="BSU_38080" /old_locus_tag="BSU38080" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 22720735" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_391687.2" /db_xref="EnsemblGenomes-Gn:BSU38080" /db_xref="EnsemblGenomes-Tr:CAB15834" /db_xref="SubtiList:BG10592" /db_xref="UniProtKB/Swiss-Prot:P39607" /translation="MKRLLVSLRVWMVFLMNWVTPDRKTAAAAVYSAQRTYQRKAAVQ AAGLVSFYEWRMAVNEEEKQKAKAAALYKRRCLQAFKESPKQERAGPHLYMAVKRR*" gene complement(3772610..3772912) /gene="ywcI" /locus_tag="BSU_38080" /old_locus_tag="BSU38080" promotor_-35 complement(3772630..3772637) /Source="Nicolas_upshift_promotors" /id="U2991" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.72027972027972" /psig="0.943056943056943" /xcortree=452 /SigmaFactorBS="caaagcaggagagagcgggcccgcaTCTTTACAtggcggtca aaaggAGGTAAAATCCCAGTCAAAAgcaaattggcgggagagataacctcttgaaaat c" /listShort="sacT" /GFF_Attribute="listLong" /label="promotor_-35" S_feature complement(3772913..3773051) /Source="Nicolas_S_feature" /locus_tag="new_3907315_3907453_c" /HighExp="T5.0H, M9-stat, S2, S4, T4.0H, S3, T3.30H, LoTm, B36, B60" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.823" /TUlongSig="NA" /TUlongPSig="NA" /label="S1467" misc_feature complement(3773036..3773055) /Source="Nicolas_upshift_promotors" /id="U2992" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.388611388611389" /psig="0.823176823176823" /xcortree=968 /SigmaFactorBS="cttctaaaaactagttggttttttcactcatattgtgacaaa gaattctctttccaCGGTCTATCATAGAGTCATGagttttgctagagccgctagtttg c" /listShort="S1467, ywcI, sacT" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(3773051) /Source="Nicolas_upshifts" /id="U2992" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.388611388611389" /psig="0.823176823176823" /xcortree=968 /SigmaFactorBS="cttctaaaaactagttggttttttcactcatattgtgacaaa gaattctctttccaCGGTCTATCATAGAGTCATGagttttgctagagccgctagtttg c" /listShort="S1467, ywcI, sacT" /GFF_Attribute="listLong" promotor_-35 3773366..3773374 /Source="Nicolas_upshift_promotors" /id="U2993" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.983016983016983" /psig="0.983016983016983" /xcortree=466 /SigmaFactorBS="gttatacacaaacaaaatccaataaatggtccaaatgacaCA AGGATTTttttgaatttTCAAGAAATATATACTAGAtctttcacattttttctaaata c" /listShort="vpr" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3773385..3773403 /Source="Nicolas_upshift_promotors" /id="U2993" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.983016983016983" /psig="0.983016983016983" /xcortree=466 /SigmaFactorBS="gttatacacaaacaaaatccaataaatggtccaaatgacaCA AGGATTTttttgaatttTCAAGAAATATATACTAGAtctttcacattttttctaaata c" /listShort="vpr" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3773386 /Source="Nicolas_upshifts" /id="U2993" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.983016983016983" /psig="0.983016983016983" /xcortree=466 /SigmaFactorBS="gttatacacaaacaaaatccaataaatggtccaaatgacaCA AGGATTTttttgaatttTCAAGAAATATATACTAGAtctttcacattttttctaaata c" /listShort="vpr" /GFF_Attribute="listLong" CDS 3773442..3775862 /gene="vpr" /locus_tag="BSU_38090" /old_locus_tag="BSU38090" /EC_number="3.4.21.-" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:15205417, 15596354, 16946274, 17666034, 18689487, 25666135" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15205417, 15596354, 16946274, 17666034, 18689487, 25666135; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="extracellular serine protease" /protein_id="NP_391688.1" /db_xref="EnsemblGenomes-Gn:BSU38090" /db_xref="EnsemblGenomes-Tr:CAB15835" /db_xref="GOA:P29141" /db_xref="InterPro:IPR000209" /db_xref="InterPro:IPR003137" /db_xref="InterPro:IPR010259" /db_xref="InterPro:IPR013783" /db_xref="InterPro:IPR015500" /db_xref="InterPro:IPR022398" /db_xref="InterPro:IPR023827" /db_xref="InterPro:IPR023828" /db_xref="InterPro:IPR025965" /db_xref="InterPro:IPR034213" /db_xref="InterPro:IPR036852" /db_xref="InterPro:IPR037045" /db_xref="SubtiList:BG10591" /db_xref="UniProtKB/Swiss-Prot:P29141" /translation="MKKGIIRFLLVSFVLFFALSTGITGVQAAPASSKTSADLEKAEV FGDIDMTTSKKTTVIVELKEKSLAEAKEAGESQSKSKLKTARTKAKNKAIKAVKNGKV NREYEQVFSGFSMKLPANEIPKLLAVKDVKAVYPNVTYKTDNMKDKDVTISEDAVSPQ MDDSAPYIGANDAWDLGYTGKGIKVAIIDTGVEYNHPDLKKNFGQYKGYDFVDNDYDP KETPTGDPRGEATDHGTHVAGTVAANGTIKGVAPDATLLAYRVLGPGGSGTTENVIAG VERAVQDGADVMNLSLGNSLNNPDWATSTALDWAMSEGVVAVTSNGNSGPNGWTVGSP GTSREAISVGATQLPLNEYAVTFGSYSSAKVMGYNKEDDVKALNNKEVELVEAGIGEA KDFEGKDLTGKVAVVKRGSIAFVDKADNAKKAGAIGMVVYNNLSGEIEANVPGMSVPT IKLSLEDGEKLVSALKAGETKTTFKLTVSKALGEQVADFSSRGPVMDTWMIKPDISAP GVNIVSTIPTHDPDHPYGYGSKQGTSMASPHIAGAVAVIKQAKPKWSVEQIKAAIMNT AVTLKDSDGEVYPHNAQGAGSARIMNAIKADSLVSPGSYSYGTFLKENGNETKNETFT IENQSSIRKSYTLEYSFNGSGISTSGTSRVVIPAHQTGKATAKVKVNTKKTKAGTYEG TVIVREGGKTVAKVPTLLIVKEPDYPRVTSVSVSEGSVQGTYQIETYLPAGAEELAFL VYDSNLDFAGQAGIYKNQDKGYQYFDWDGTINGGTKLPAGEYYLLAYAANKGKSSQVL TEEPFTVE*" gene 3773442..3775862 /gene="vpr" /locus_tag="BSU_38090" /old_locus_tag="BSU38090" upshifts 3773600 /Source="Nicolas_upshifts" /id="U2994" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.677322677322677" /psig="0.986013986013986" /xcortree=625 /SigmaFactorBS="aaaaacgtcggctgatctggaaaaagccgaggtattcggtga tatcgatatgacgacaagcaaaaaaacAACCGTTATAGTGGAATTAAaagaaaaatcc t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" misc_feature 3773609..3773628 /Source="Nicolas_upshift_promotors" /id="U2994" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.677322677322677" /psig="0.986013986013986" /xcortree=625 /SigmaFactorBS="aaaaacgtcggctgatctggaaaaagccgaggtattcggtga tatcgatatgacgacaagcaaaaaaacAACCGTTATAGTGGAATTAAaagaaaaatcc t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" downshifts 3775850 /Source="Nicolas_upshifts" /id="D1968" /incds=0 /nref=7 /ntot=104 /MaxReadThrough="0.60305" /MaxDrop="5.33856" /score="26.8487936" /energy="-16.5" /TU="NA" /idTUdmin="U2993" /TUdmin=6 /isTUend="TRUE" CDS complement(3775900..3776901) /gene="ywcH" /locus_tag="BSU_38100" /old_locus_tag="BSU38100" /EC_number="1.14.-.-" /function="16.11: Scavenge (Catabolism)" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 10913069, 15774866; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative monooxygenase" /protein_id="NP_391689.1" /db_xref="EnsemblGenomes-Gn:BSU38100" /db_xref="EnsemblGenomes-Tr:CAB15836" /db_xref="GOA:P39606" /db_xref="InterPro:IPR011251" /db_xref="InterPro:IPR019949" /db_xref="InterPro:IPR036661" /db_xref="SubtiList:BG10590" /db_xref="UniProtKB/Swiss-Prot:P39606" /translation="MVSLSILDQSPVSEGSNAETALQQTVALAQAAEDLGYKRFWVSE HHFSKRLAGSSPEVLISHIAAKTKRIRVGSGGVMLPHYSAYKVAENFRVLEGLTPGRI DLGLGRAPGGMPIASWALNDGGKRNADQYPQQIKELTMYLHDLADDKHRFPNLTAAPH ISTAPDVWLLGSSGESALLAAESGAGYMFAHFINGEGGEGTVRQYKRRFKPSVLGDTP RAAVAVFVLCADTEEKAEELGAVLDFTLLAGEQGIPLEGVPSYEAVRKNTYSPYEQRR IADNRNRMIVGTKEQVKERLLALSNAYETEEIMVVTITHHFEDKLRSYRLLQEAFAD* " gene complement(3775900..3776901) /gene="ywcH" /locus_tag="BSU_38100" /old_locus_tag="BSU38100" S_feature complement(3776902..3777063) /Source="Nicolas_S_feature" /locus_tag="new_3911304_3911465_c" /HighExp="Etha, Diami, dia15, LPhT, dia5, H2O2, B60, LBGstat, M9-stat, LBGtran" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="SigWXY" /TUlongPSig=1 /label="S1468" CDS complement(3777075..3777824) /gene="nfrAA" /locus_tag="BSU_38110" /old_locus_tag="BSU38110" /EC_number="1.5.1.38" /function="16.11: Scavenge (Catabolism)" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:9535080, 9836433, 10913069, 15774866, 20727352, 20862523, 24847778, 25288929" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9535080, 9836433, 10913069, 15774866, 20727352, 20862523, 24847778, 25288929; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="FMN-containing NADPH-linked nitro/flavin reductase" /protein_id="NP_391690.1" /db_xref="EnsemblGenomes-Gn:BSU38110" /db_xref="EnsemblGenomes-Tr:CAB15837" /db_xref="GOA:P39605" /db_xref="InterPro:IPR000415" /db_xref="InterPro:IPR016446" /db_xref="InterPro:IPR029479" /db_xref="PDB:3N2S" /db_xref="SubtiList:BG10589" /db_xref="UniProtKB/Swiss-Prot:P39605" /translation="MNNTIETILNHRSIRSFTDQLLTAEEIDTLVKSAQAASTSSYVQ AYSIIGVSDPEKKRELSVLAGNQPYVEKNGHFFVFCADLYRHQQLAEEKGEHISELLE NTEMFMVSLIDAALAAQNMSIAAESMGLGICYIGGIRNELDKVTEVLQTPDHVLPLFG LAVGHPANLSGKKPRLPKQAVYHENTYNVNTDDFRHTMNTYDKTISDYYRERTNGKRE ETWSDQILNFMKQKPRTYLNDYVKEKGFNKN*" gene complement(3777075..3777824) /gene="nfrAA" /locus_tag="BSU_38110" /old_locus_tag="BSU38110" downshifts complement(3777108) /Source="Nicolas_upshifts" /id="D1969" /incds=0 /nref=11 /ntot=191 /MaxReadThrough="5.92216" /MaxDrop="3.39651" /score="17.7447455" /energy="-9.9" /TU="U2995" /idTUdmin="U2996" /TUdmin=770 /isTUend="FALSE" promotor_-10 complement(3777842..3777861) /Source="Nicolas_upshift_promotors" /id="U2995" /multdbtbs="SigA,SigD" /comp="M7" /sig="SigA" /pcomp="0.792207792207792" /psig=1 /xcortree=2037 /SigmaFactorBS="gcctttacagaggctgtctttttttgtgcagagcatttcaCT TTtgagatcactttttTTCGGATATGATAAAAAGTGataaggaggtttttgtgatgaa t" /listShort="nfrA, S1468, ywcH" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3777859) /Source="Nicolas_upshifts" /id="U2995" /multdbtbs="SigA,SigD" /comp="M7" /sig="SigA" /pcomp="0.792207792207792" /psig=1 /xcortree=2037 /SigmaFactorBS="gcctttacagaggctgtctttttttgtgcagagcatttcaCT TTtgagatcactttttTTCGGATATGATAAAAAGTGataaggaggtttttgtgatgaa t" /listShort="nfrA, S1468, ywcH" /GFF_Attribute="listLong" promotor_-35 complement(3777876..3777879) /Source="Nicolas_upshift_promotors" /id="U2995" /multdbtbs="SigA,SigD" /comp="M7" /sig="SigA" /pcomp="0.792207792207792" /psig=1 /xcortree=2037 /SigmaFactorBS="gcctttacagaggctgtctttttttgtgcagagcatttcaCT TTtgagatcactttttTTCGGATATGATAAAAAGTGataaggaggtttttgtgatgaa t" /listShort="nfrA, S1468, ywcH" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3777930..3779111) /gene="rodA" /locus_tag="BSU_38120" /old_locus_tag="BSU38120" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:9622350, 15612918, 15849754, 16850406, 28085152" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9622350, 15612918, 15849754, 16850406, 28085152; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="glycosyltransferase involved in extension of thelateral walls of the cell" /protein_id="NP_391691.1" /db_xref="EnsemblGenomes-Gn:BSU38120" /db_xref="EnsemblGenomes-Tr:CAB15838" /db_xref="GOA:P39604" /db_xref="InterPro:IPR001182" /db_xref="InterPro:IPR018365" /db_xref="SubtiList:BG10588" /db_xref="UniProtKB/Swiss-Prot:P39604" /translation="MSRYKKQQSPFYQGDLIFIFGVFFIISVVSIYAAGQFGQYGNTD WIQQIVFYLLGAVAITVLLYFDLEQLEKLSLYIFIIGILSLIILKISPESIAPVIKGA KSWFRIGRITIQPSEFMKVGLIMMLASVIGKANPKGVRTLRDDIHLLLKIAGVAVIPV GLILMQDAGTAGICMFIVLVMVFMSGINWKLIAIIAGSGILLISLILLVMINFPDVAK SVGIQDYQIKRVTSWVSASNETQEDSNDSWQVDQAIMAIGSGGILGNGISNLKVYVPE STTDFIFSIIGESFGFIGCAIVVIMFFFLIYRLVVLIDKIHPFNRFASFFCVGYTALI VIHTFQNIGMNIGIMPVTGIPLLFVSYGGSSTLSTLIGFGIVYNASVQLTKYRSYLFN S*" gene complement(3777930..3779111) /gene="rodA" /locus_tag="BSU_38120" /old_locus_tag="BSU38120" downshifts complement(3777944) /Source="Nicolas_upshifts" /id="D1970" /incds=0 /nref=20 /ntot=124 /MaxReadThrough="3.38052" /MaxDrop="5.67563" /score="31.4805549" /energy="-13.3" /TU="U2996" /idTUdmin="U2996" /TUdmin="-66" /isTUend="FALSE" S_feature complement(3779112..3779243) /Source="Nicolas_S_feature" /locus_tag="new_3913514_3913645_c" /HighExp="Heat, T0.30H, H2O2, T1.0H, Salt, Paraq, T1.30H, LBGstat, Oxctl, G180" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigWXY" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1469" promotor_-10 complement(3779237..3779252) /Source="Nicolas_upshift_promotors" /id="U2996" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1657 /SigmaFactorBS="tttttttcatttgaaaagttttgtgtcaatCGAAACATTTcg gtttatgatACGTCATATTTCGTGTagctgaaaaagcgccgcaaatgctgaaaaaaca t" /listShort="S1469, rodA" /listLong="nfrA, S1468, ywcH" /label="promotor_-10" upshifts complement(3779243) /Source="Nicolas_upshifts" /id="U2996" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1657 /SigmaFactorBS="tttttttcatttgaaaagttttgtgtcaatCGAAACATTTcg gtttatgatACGTCATATTTCGTGTagctgaaaaagcgccgcaaatgctgaaaaaaca t" /listShort="S1469, rodA" /listLong="nfrA, S1468, ywcH" promotor_-35 complement(3779264..3779273) /Source="Nicolas_upshift_promotors" /id="U2996" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1657 /SigmaFactorBS="tttttttcatttgaaaagttttgtgtcaatCGAAACATTTcg gtttatgatACGTCATATTTCGTGTagctgaaaaagcgccgcaaatgctgaaaaaaca t" /listShort="S1469, rodA" /listLong="nfrA, S1468, ywcH" /label="promotor_-35" promotor_-35 3779478..3779485 /Source="Nicolas_upshift_promotors" /id="U2997" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.99000999000999" /psig=1 /xcortree=437 /SigmaFactorBS="aaaaaataagacgatagatccagtccatttctgcaaaaacac GTATCAATttctggaaaaCATGGTATAATAATTGTAACagaatgttcaaaaaacaatc a" /listShort="S1470, ywcE" /GFF_Attribute="listLong" /label="promotor_-35" S_feature 3779496..3779606 /Source="Nicolas_S_feature" /locus_tag="new_3913898_3914008" /HighExp="M9-stat, T0.30H, T1.30H, T1.0H, T4.0H, T2.30H, T3.30H, T3.0H, T5.0H, T2.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1470" promotor_-10 3779496..3779515 /Source="Nicolas_upshift_promotors" /id="U2997" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.99000999000999" /psig=1 /xcortree=437 /SigmaFactorBS="aaaaaataagacgatagatccagtccatttctgcaaaaacac GTATCAATttctggaaaaCATGGTATAATAATTGTAACagaatgttcaaaaaacaatc a" /listShort="S1470, ywcE" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3779496 /Source="Nicolas_upshifts" /id="U2997" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.99000999000999" /psig=1 /xcortree=437 /SigmaFactorBS="aaaaaataagacgatagatccagtccatttctgcaaaaacac GTATCAATttctggaaaaCATGGTATAATAATTGTAACagaatgttcaaaaaacaatc a" /listShort="S1470, ywcE" /GFF_Attribute="listLong" CDS 3779607..3779870 /gene="ywcE" /locus_tag="BSU_38130" /old_locus_tag="BSU38130" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:16159778" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16159778; Product type f: factor" /codon_start=1 /transl_table=11 /product="holin-like protein required for proper spore morphogenesis and germination" /protein_id="NP_391692.1" /db_xref="EnsemblGenomes-Gn:BSU38130" /db_xref="EnsemblGenomes-Tr:CAB15839" /db_xref="GOA:P39603" /db_xref="InterPro:IPR020185" /db_xref="SubtiList:BG10587" /db_xref="UniProtKB/Swiss-Prot:P39603" /translation="MMDMFFAYLLVASATPLFIWLDNKKVALSAIPPIILMWVFFFFY ATESLSPLGHTLMIILFAVNVIVAHIAAFIIYGLPYLRRKRSS*" gene 3779607..3779870 /gene="ywcE" /locus_tag="BSU_38130" /old_locus_tag="BSU38130" downshifts 3779760 /Source="Nicolas_upshifts" /id="D1971" /incds=1 /nref=1 /ntot=99 /MaxReadThrough="6.85004" /MaxDrop="2.5697" /score="27.9247684" /energy="-11.4" /TU="U2997" /idTUdmin="U2997" /TUdmin="-110" /isTUend="FALSE" downshifts 3779876 /Source="Nicolas_upshifts" /id="D1972" /incds=0 /nref=7 /ntot=90 /MaxReadThrough="2.04756" /MaxDrop="6.52141" /score="27.9247684" /energy="-11.4" /TU="NA" /idTUdmin="U2997" /TUdmin=6 /isTUend="TRUE" CDS complement(3779913..3780287) /gene="qoxD" /locus_tag="BSU_38140" /old_locus_tag="BSU38140" /EC_number="1.10.3.12" /function="16.10: Respire" /experiment="publication(s) with functional evidences, PMID:1316894, 7495838, 7575098, 10551842, 15849754, 16850406, 26196462" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1316894, 7495838, 7575098, 10551842, 15849754, 16850406, 26196462; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="cytochrome aa3-600 quinol oxidase (subunit IV)" /protein_id="NP_391693.1" /db_xref="EnsemblGenomes-Gn:BSU38140" /db_xref="EnsemblGenomes-Tr:CAB15840" /db_xref="GOA:P34959" /db_xref="InterPro:IPR005171" /db_xref="InterPro:IPR014250" /db_xref="SubtiList:BG10586" /db_xref="UniProtKB/Swiss-Prot:P34959" /translation="MANKSAEHSHFPWKHIVGFILSIVLTLLALWVAVYTDLSSSAKL WIIFGFAFIQAALQLLMFMHMTESENGTIQVGNTLFGFFGAIVIVLGSIWIFAAHYHH GDHMDGNPPGGAEHSEHSGHNE*" gene complement(3779913..3780287) /gene="qoxD" /locus_tag="BSU_38140" /old_locus_tag="BSU38140" downshifts complement(3779924) /Source="Nicolas_upshifts" /id="D1973" /incds=0 /nref=222 /ntot=267 /MaxReadThrough="2.42368" /MaxDrop="9.0593" /score="21.3154492" /energy="-11.4" /TU="NA" /idTUdmin="U3000" /TUdmin=0 /isTUend="TRUE" CDS complement(3780289..3780903) /gene="qoxC" /locus_tag="BSU_38150" /old_locus_tag="BSU38150" /EC_number="1.10.3.12" /function="16.10: Respire" /experiment="publication(s) with functional evidences, PMID:1316894, 7495838, 7575098, 10551842, 15849754, 16850406, 26196462" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1316894, 7495838, 7575098, 10551842, 15849754, 16850406, 26196462; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="cytochrome aa3-600 quinol oxidase (subunit III)" /protein_id="NP_391694.1" /db_xref="EnsemblGenomes-Gn:BSU38150" /db_xref="EnsemblGenomes-Tr:CAB15841" /db_xref="GOA:P34958" /db_xref="InterPro:IPR000298" /db_xref="InterPro:IPR013833" /db_xref="InterPro:IPR014246" /db_xref="InterPro:IPR024791" /db_xref="InterPro:IPR033946" /db_xref="InterPro:IPR035973" /db_xref="SubtiList:BG10585" /db_xref="UniProtKB/Swiss-Prot:P34958" /translation="MEHAEHGNSNAPMEYQSETGRLNILGFWIFLGAEIVLFSTLFAT FFVLKNRTAGGVLPDELFEVNLVMIMTFLLLISSFTCGIAVHEMRRGSLKGVVIWTII TLLLGAGFVGCEINEFVHYVHEGAALSTSAFWSGFFVLLGTHGTHVTIGIFWITGILI QLKKRGLTPQTSSKIFISSLYWHFLDVVWIFIFTGVYLMGLGGL*" gene complement(3780289..3780903) /gene="qoxC" /locus_tag="BSU_38150" /old_locus_tag="BSU38150" CDS complement(3780917..3782866) /gene="qoxB" /locus_tag="BSU_38160" /old_locus_tag="BSU38160" /EC_number="1.10.3.12" /function="16.10: Respire" /experiment="publication(s) with functional evidences, PMID:1316894, 7495838, 7575098, 10551842, 15849754, 16850406, 22720735, 26196462" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1316894, 7495838, 7575098, 10551842, 15849754, 16850406, 22720735, 26196462; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="cytochrome aa3-600 quinol oxidase (subunit I)" /protein_id="NP_391695.1" /db_xref="EnsemblGenomes-Gn:BSU38160" /db_xref="EnsemblGenomes-Tr:CAB15842" /db_xref="GOA:P34956" /db_xref="InterPro:IPR000883" /db_xref="InterPro:IPR014233" /db_xref="InterPro:IPR023615" /db_xref="InterPro:IPR023616" /db_xref="InterPro:IPR036927" /db_xref="SubtiList:BG10584" /db_xref="UniProtKB/Swiss-Prot:P34956" /translation="MKFKWDEFFVTGDPLILGAQVSIALSTIAIIFVLTYFKKWKWLW SEWITTVDHKKLGIMYIISAVIMLFRGGVDGLMMRAQLALPNNSFLDSNHYNEIFTTH GTIMIIFMAMPFLIGLINVVVPLQIGARDVAFPYLNNLSFWTFFVGAMLFNISFVIGG SPNAGWTSYMPLASNDMSPGPGENYYLLGLQIAGIGTLMTGINFMVTILKMRTKGMTL MRMPMFTWTTLITMVIIVFAFPVLTVALALLSFDRLFGAHFFTLEAGGMPMLWANLFW IWGHPEVYIVILPAFGIFSEIISSFARKQLFGYKAMVGSIIAISVLSFLVWTHHFFTM GNSASVNSFFSITTMAISIPTGVKIFNWLFTMYKGRISFTTPMLWALAFIPNFVIGGV TGVMLAMAAADYQYHNTYFLVSHFHYVLIAGTVFACFAGFIFWYPKMFGHKLNERIGK WFFWIFMIGFNICFFPQYFLGLQGMPRRIYTYGPNDGWTTLNFISTVGAFMMGVGFLI LCYNIYYSFRYSTREISGDSWGVGRTLDWATSSAIPPHYNFAVLPEVKSQDAFLHMKE EKTELYPESKFKKIHMPSNSGRPFFMSVAFGLAGFGLVFEWYWMGVVGLIGVLLCMVL RSFEYDNGYYISVDEIKETERKISE*" gene complement(3780917..3782866) /gene="qoxB" /locus_tag="BSU_38160" /old_locus_tag="BSU38160" misc_feature 3782130..3782149 /Source="Nicolas_upshift_promotors" /id="U2998" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.869130869130869" /psig="0.894105894105894" /xcortree=62 /SigmaFactorBS="gcttccaatgtgaaaaagtgagcgccgaacaaacgatcaaat gataaaagtgctAATGCTACTGTAAGTACAGGgaacgcaaacacgataataaccattg t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 3782136 /Source="Nicolas_upshifts" /id="U2998" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.869130869130869" /psig="0.894105894105894" /xcortree=62 /SigmaFactorBS="gcttccaatgtgaaaaagtgagcgccgaacaaacgatcaaat gataaaagtgctAATGCTACTGTAAGTACAGGgaacgcaaacacgataataaccattg t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_no_box 3782560..3782660 /Source="Nicolas_upshift_promotors" /id="U2999" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.915084915084915" /psig="0.002997002997003" /xcortree=78 /SigmaFactorBS="cgtgagttgtaaaaatttcattatagtggtttgagtctaaaa aactgttattcggaagcgctagctgggcacgcatcatcagaccgtcgacaccgccacg g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_no_box" upshifts 3782620 /Source="Nicolas_upshifts" /id="U2999" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.915084915084915" /psig="0.002997002997003" /xcortree=78 /SigmaFactorBS="cgtgagttgtaaaaatttcattatagtggtttgagtctaaaa aactgttattcggaagcgctagctgggcacgcatcatcagaccgtcgacaccgccacg g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" downshifts 3782730 /Source="Nicolas_upshifts" /id="D1974" /incds=1 /nref=1 /ntot=73 /MaxReadThrough="3.07388" /MaxDrop="3.44223" /score="-7.14620582" /energy="-8.1" /TU="U2999" /idTUdmin="U2999" /TUdmin="-154" /isTUend="FALSE" CDS complement(3782894..3783859) /gene="qoxA" /locus_tag="BSU_38170" /old_locus_tag="BSU38170" /EC_number="1.10.3.12" /function="16.10: Respire" /experiment="publication(s) with functional evidences, PMID:1316894, 7495838, 7575098, 10551842, 22720735, 26196462" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1316894, 7495838, 7575098, 10551842, 22720735, 26196462; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="cytochrome aa3-600 quinol oxidase (subunit II)" /protein_id="NP_391696.2" /db_xref="EnsemblGenomes-Gn:BSU38170" /db_xref="EnsemblGenomes-Tr:CAB15843" /db_xref="GOA:P34957" /db_xref="InterPro:IPR002429" /db_xref="InterPro:IPR006332" /db_xref="InterPro:IPR006333" /db_xref="InterPro:IPR008972" /db_xref="InterPro:IPR011759" /db_xref="InterPro:IPR034227" /db_xref="InterPro:IPR036257" /db_xref="SubtiList:BG10583" /db_xref="UniProtKB/Swiss-Prot:P34957" /translation="MIFLFRALKPLLVLALLTVVFVLGGCSNASVLDPKGPVAEQQSD LILLSIGFMLFIVGVVFVLFTIILVKYRDRKGKDNGSYNPEIHGNTFLEVVWTVIPIL IVIALSVPTVQTIYSLEKAPEATKDKEPLVVYATSVDWKWVFSYPEQDIETVNYLNIP VDRPILFKISSADSMASLWIPQLGGQKYAMAGMLMDQYLQADKVGTYEGRNANFTGEH FADQEFDVNAVTEKDFNSWVKKTQNEAPKLTKEKYDELMLPENVDELTFSSTHLKYVD HGQDAEYAMEARKRLGYQAVSPHSKTDPFENVKKNEFKKSDDTEE*" gene complement(3782894..3783859) /gene="qoxA" /locus_tag="BSU_38170" /old_locus_tag="BSU38170" S_feature complement(3783860..3783928) /Source="Nicolas_S_feature" /locus_tag="new_3918262_3918330_c" /HighExp="M0t90, M40t90, Lbtran, Lbstat, M40t45, S2, nit, ferm, LBGstat, LBGtran" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA, SigA, SigEF" /TUshortPSig="0.626, 1, 1, 0.95" /TUlongSig="NA" /TUlongPSig="NA" /label="S1471" promotor_-10 complement(3783915..3783934) /Source="Nicolas_upshift_promotors" /id="U3000" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.30969030969031" /psig="0.626373626373626" /xcortree=2709 /SigmaFactorBS="taagcgaaaatgggatgaagtttataaaaaaataaagCTAAT aagtgaagttttTGATAGCATAACAAAGTAGAgaaaagattttgaggaagtatgcact t" /listShort="S1471, qoxA, qoxB, qoxC, qoxD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3783928) /Source="Nicolas_upshifts" /id="U3000" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.30969030969031" /psig="0.626373626373626" /xcortree=2709 /SigmaFactorBS="taagcgaaaatgggatgaagtttataaaaaaataaagCTAAT aagtgaagttttTGATAGCATAACAAAGTAGAgaaaagattttgaggaagtatgcact t" /listShort="S1471, qoxA, qoxB, qoxC, qoxD" /GFF_Attribute="listLong" S_feature complement(3783930..3784115) /Source="Nicolas_S_feature" /locus_tag="new_3918332_3918517_c" /HighExp="LBGstat, Heat, G150, G135, LBGtran, G180, BMM, Salt, LBGexp, Oxctl" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA, SigEF" /TUshortPSig="1, 1, 0.95" /TUlongSig="NA" /TUlongPSig="NA" /label="S1472" promotor_-35 complement(3783947..3783951) /Source="Nicolas_upshift_promotors" /id="U3000" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.30969030969031" /psig="0.626373626373626" /xcortree=2709 /SigmaFactorBS="taagcgaaaatgggatgaagtttataaaaaaataaagCTAAT aagtgaagttttTGATAGCATAACAAAGTAGAgaaaagattttgaggaagtatgcact t" /listShort="S1471, qoxA, qoxB, qoxC, qoxD" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 3784046..3784051 /Source="Nicolas_upshift_promotors" /id="U3001" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.903096903096903" /psig="0.903096903096903" /xcortree=792 /SigmaFactorBS="tgctccaactttattcacatctatcgcttaagatGAAAAGtt tctagttatttccGCATATAAAGTAAAGAAAGatgatgaagaactaattctgacaaat t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3784067..3784085 /Source="Nicolas_upshift_promotors" /id="U3001" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.903096903096903" /psig="0.903096903096903" /xcortree=792 /SigmaFactorBS="tgctccaactttattcacatctatcgcttaagatGAAAAGtt tctagttatttccGCATATAAAGTAAAGAAAGatgatgaagaactaattctgacaaat t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3784072 /Source="Nicolas_upshifts" /id="U3001" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.903096903096903" /psig="0.903096903096903" /xcortree=792 /SigmaFactorBS="tgctccaactttattcacatctatcgcttaagatGAAAAGtt tctagttatttccGCATATAAAGTAAAGAAAGatgatgaagaactaattctgacaaat t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 complement(3784106..3784125) /Source="Nicolas_upshift_promotors" /id="U3002" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.583416583416583" /psig=1 /xcortree=2699 /SigmaFactorBS="atctagaaagtttaacaaaatgaaatttttgATTGAcctaag ttttttatTGTGGTAAACCTTAATTTGTcagaattagttcttcatcatctttctttac t" /listShort="S1472, S1471, qoxA, qoxB, qoxC, qoxD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3784115) /Source="Nicolas_upshifts" /id="U3002" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.583416583416583" /psig=1 /xcortree=2699 /SigmaFactorBS="atctagaaagtttaacaaaatgaaatttttgATTGAcctaag ttttttatTGTGGTAAACCTTAATTTGTcagaattagttcttcatcatctttctttac t" /listShort="S1472, S1471, qoxA, qoxB, qoxC, qoxD" /GFF_Attribute="listLong" S_feature complement(3784117..3784226) /Source="Nicolas_S_feature" /locus_tag="new_3918519_3918628_c" /HighExp="Heat, Salt, LBGstat, BMM, Oxctl, H2O2, MG 15, UNK1, MG-0.1, MG 25" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigEF" /TUshortPSig="1, 0.95" /TUlongSig="NA" /TUlongPSig="NA" /label="S1473" promotor_-35 complement(3784140..3784144) /Source="Nicolas_upshift_promotors" /id="U3002" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.583416583416583" /psig=1 /xcortree=2699 /SigmaFactorBS="atctagaaagtttaacaaaatgaaatttttgATTGAcctaag ttttttatTGTGGTAAACCTTAATTTGTcagaattagttcttcatcatctttctttac t" /listShort="S1472, S1471, qoxA, qoxB, qoxC, qoxD" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 3784182 /Source="Nicolas_upshifts" /id="D1975" /incds=0 /nref=3 /ntot=21 /MaxReadThrough="2.69533" /MaxDrop="4.01393" /score="13.5410442" /energy="-16.4" /TU="U3001" /idTUdmin="U3001" /TUdmin="-44" /isTUend="FALSE" promotor_-10 complement(3784211..3784230) /Source="Nicolas_upshift_promotors" /id="U3003" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.987012987012987" /psig=1 /xcortree=2528 /SigmaFactorBS="tacggacaattcagagcatattggctcttcattgcgCCTTTt ctttcaatatttgaTGCGTTAAAATGGTAACCGTgtgaaaagatgctagacgaggaaa a" /listShort="S1473, S1472, S1471, qoxA, qoxB, qoxC, qoxD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3784226) /Source="Nicolas_upshifts" /id="U3003" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.987012987012987" /psig=1 /xcortree=2528 /SigmaFactorBS="tacggacaattcagagcatattggctcttcattgcgCCTTTt ctttcaatatttgaTGCGTTAAAATGGTAACCGTgtgaaaagatgctagacgaggaaa a" /listShort="S1473, S1472, S1471, qoxA, qoxB, qoxC, qoxD" /GFF_Attribute="listLong" promotor_-35 complement(3784246..3784250) /Source="Nicolas_upshift_promotors" /id="U3003" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.987012987012987" /psig=1 /xcortree=2528 /SigmaFactorBS="tacggacaattcagagcatattggctcttcattgcgCCTTTt ctttcaatatttgaTGCGTTAAAATGGTAACCGTgtgaaaagatgctagacgaggaaa a" /listShort="S1473, S1472, S1471, qoxA, qoxB, qoxC, qoxD" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(3784304..3784322) /Source="Nicolas_upshift_promotors" /id="U3004" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.95004995004995" /psig="0.95004995004995" /xcortree=1019 /SigmaFactorBS="aactcatcatgcaacacatcctattttttatttatttgCTTA TAtcattcctcttttttGTATAAGATAAACAACTGGatgctctcataaaaaaatacgg a" /listShort="S1473, S1472, S1471, qoxA, qoxB, qoxC, qoxD" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 3784309..3784315 /Source="Nicolas_upshift_promotors" /id="U3005" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.996003996003996" /psig="0.996003996003996" /xcortree=241 /SigmaFactorBS="ctgaattgtccgtatttttttatgagagcatccagtTGTTTA TcttatacaaaaaagAGGAATGATATAAGCAAATaaataaaaaataggatgtgttgca t" /listShort="ywzA" /GFF_Attribute="listLong" /label="promotor_-35" upshifts complement(3784321) /Source="Nicolas_upshifts" /id="U3004" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.95004995004995" /psig="0.95004995004995" /xcortree=1019 /SigmaFactorBS="aactcatcatgcaacacatcctattttttatttatttgCTTA TAtcattcctcttttttGTATAAGATAAACAACTGGatgctctcataaaaaaatacgg a" /listShort="S1473, S1472, S1471, qoxA, qoxB, qoxC, qoxD" /GFF_Attribute="listLong" promotor_-10 3784330..3784348 /Source="Nicolas_upshift_promotors" /id="U3005" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.996003996003996" /psig="0.996003996003996" /xcortree=241 /SigmaFactorBS="ctgaattgtccgtatttttttatgagagcatccagtTGTTTA TcttatacaaaaaagAGGAATGATATAAGCAAATaaataaaaaataggatgtgttgca t" /listShort="ywzA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3784333 /Source="Nicolas_upshifts" /id="U3005" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.996003996003996" /psig="0.996003996003996" /xcortree=241 /SigmaFactorBS="ctgaattgtccgtatttttttatgagagcatccagtTGTTTA TcttatacaaaaaagAGGAATGATATAAGCAAATaaataaaaaataggatgtgttgca t" /listShort="ywzA" /GFF_Attribute="listLong" promotor_-35 complement(3784338..3784343) /Source="Nicolas_upshift_promotors" /id="U3004" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.95004995004995" /psig="0.95004995004995" /xcortree=1019 /SigmaFactorBS="aactcatcatgcaacacatcctattttttatttatttgCTTA TAtcattcctcttttttGTATAAGATAAACAACTGGatgctctcataaaaaaatacgg a" /listShort="S1473, S1472, S1471, qoxA, qoxB, qoxC, qoxD" /GFF_Attribute="listLong" /label="promotor_-35" CDS 3784375..3784620 /gene="ywzA" /locus_tag="BSU_38180" /old_locus_tag="BSU38180" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_391697.2" /db_xref="EnsemblGenomes-Gn:BSU38180" /db_xref="EnsemblGenomes-Tr:CAB15844" /db_xref="GOA:O32282" /db_xref="InterPro:IPR007341" /db_xref="SubtiList:BG14162" /db_xref="UniProtKB/Swiss-Prot:O32282" /translation="MSFLISLIVAIIIGWLGSLFVKGDMPGGIIGSMIAGLIGAWIGH GLLGTWGPHLAGFAIIPAVIGAAIVVFLVSLLTRKRG*" gene 3784375..3784620 /gene="ywzA" /locus_tag="BSU_38180" /old_locus_tag="BSU38180" downshifts 3784602 /Source="Nicolas_upshifts" /id="D1976" /incds=0 /nref=125 /ntot=189 /MaxReadThrough="2.63086" /MaxDrop="7.72876" /score="13.5410442" /energy="-16.4" /TU="NA" /idTUdmin="U3005" /TUdmin=1 /isTUend="TRUE" CDS complement(3784691..3786232) /gene="galT" /locus_tag="BSU_38190" /old_locus_tag="BSU38190" /EC_number="2.7.7.12" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:2104611, 9555917, 11790749" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 2104611, 9555917, 11790749; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="galactose-1-phosphate uridyltransferase" /protein_id="NP_391698.2" /db_xref="EnsemblGenomes-Gn:BSU38190" /db_xref="EnsemblGenomes-Tr:CAB15845" /db_xref="GOA:P39575" /db_xref="InterPro:IPR000766" /db_xref="InterPro:IPR005849" /db_xref="InterPro:IPR005850" /db_xref="InterPro:IPR023425" /db_xref="SubtiList:BG10582" /db_xref="UniProtKB/Swiss-Prot:P39575" /translation="MSIIEHLEQLLEYGLERKLISIWDREYTRNRLYEALGITHPEPN SSTSIKQSQSLPDLLAPIYKWAAETGRMEADTDTYRDLLSAKLMGCFVPAPSEVIRKF EETKALYGPKQATKEFYQYSEDVYYIRTDRIAKNVHWTVPTEYGELEMTINLSKPEKD PKAIAAAKEQEQTNYPMCLLCKENVGFEGSVNHPARQNHRIIPVILEDEQWFLQFSPY VYYPEHCIVLKGEHEPMEISKKTFERLLSFLGQYPHYFIGSNADLPIVGGSILSHDHF QGGAHDFPMARAEAEDVYELNDYPGVSLGLVKWPMSVLRLQGDEPGHVAEAADHIFRT WQTYSDEKAGIAAYTGDTPHNTVTPIARRRGDLYELDIVLRNNRTDEEHPLGIFHPHQ EVHHIKKENIGLIEVMGLAILPGRLQEEMKETAAALCSADPKTALEQNPLTAKHSEWA LRTMEKRTITKENVDLVIKEELGHVFARILEHAGVFKQTAEGKQAFRRFIDQLGAKPV KSLNR*" gene complement(3784691..3786232) /gene="galT" /locus_tag="BSU_38190" /old_locus_tag="BSU38190" downshifts complement(3784720) /Source="Nicolas_upshifts" /id="D1977" /incds=0 /nref=190 /ntot=254 /MaxReadThrough="0.3431" /MaxDrop="6.63153" /score="21.0691542" /energy="-14.7" /TU="NA" /idTUdmin="U3006" /TUdmin=0 /isTUend="TRUE" CDS complement(3786236..3787408) /gene="galK" /locus_tag="BSU_38200" /old_locus_tag="BSU38200" /EC_number="2.7.1.6" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:2104611, 9555917" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 2104611, 9555917; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="galactokinase" /protein_id="NP_391699.1" /db_xref="EnsemblGenomes-Gn:BSU38200" /db_xref="EnsemblGenomes-Tr:CAB15846" /db_xref="GOA:P39574" /db_xref="InterPro:IPR000705" /db_xref="InterPro:IPR006203" /db_xref="InterPro:IPR006204" /db_xref="InterPro:IPR006206" /db_xref="InterPro:IPR013750" /db_xref="InterPro:IPR014721" /db_xref="InterPro:IPR019539" /db_xref="InterPro:IPR019741" /db_xref="InterPro:IPR020568" /db_xref="InterPro:IPR022963" /db_xref="InterPro:IPR036554" /db_xref="SubtiList:BG10581" /db_xref="UniProtKB/Swiss-Prot:P39574" /translation="MREELKGIFASVFGEKEGLRFFFAPGRVNLIGEHTDYNGGHVFP CALTMGTYAAVAERNDGLVRMYSDNFRNAGIKECSLDDIRYQKEDDWANYPKGVIYEF QQRGYAVPHGFDIVFSGNIPNGAGLSSSASIELLMGVVLQSYFHPEVDALELVKMAQH AENHFIGVNCGIMDQFAIGMGKKHHAMLLNCDTLDYEYSKLNVSGLALVIANTNKKRT LADSSYNTRRQECNDALLDLKKGLDIAALGDIKPSDFDAHSSLIQNETNRRRAKHAVY ENHRAIKTAHMFKENNIDEIGQLMKESHLSLKDDYEVTCPELDELVFAAWDHEGVIGS RMTGAGFGGCTISIVKDEFVDDFIQKVGDRYQEKTGLRADFYVADIGEGARELKGE*" gene complement(3786236..3787408) /gene="galK" /locus_tag="BSU_38200" /old_locus_tag="BSU38200" promotor_-10 complement(3787426..3787444) /Source="Nicolas_upshift_promotors" /id="U3006" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=170 /SigmaFactorBS="caaaagaagaaggggtatgagaggactgcagcatatgatctg cCGTTTTCtatgaagaaataagGGGAATAAAAAATAAAAACcagaaaggtgattgcac a" /listShort="galK, galT" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3787448) /Source="Nicolas_upshifts" /id="U3006" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=170 /SigmaFactorBS="caaaagaagaaggggtatgagaggactgcagcatatgatctg cCGTTTTCtatgaagaaataagGGGAATAAAAAATAAAAACcagaaaggtgattgcac a" /listShort="galK, galT" /GFF_Attribute="listLong" promotor_-35 complement(3787459..3787465) /Source="Nicolas_upshift_promotors" /id="U3006" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=170 /SigmaFactorBS="caaaagaagaaggggtatgagaggactgcagcatatgatctg cCGTTTTCtatgaagaaataagGGGAATAAAAAATAAAAACcagaaaggtgattgcac a" /listShort="galK, galT" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3787489..3787872) /gene="ywcD" /locus_tag="BSU_38210" /old_locus_tag="BSU38210" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 9882654, 15849754, 16850406, 18192405; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative cell wall glycosylation protein" /protein_id="NP_391700.1" /db_xref="EnsemblGenomes-Gn:BSU38210" /db_xref="EnsemblGenomes-Tr:CAB15847" /db_xref="GOA:P39602" /db_xref="InterPro:IPR007267" /db_xref="SubtiList:BG10580" /db_xref="UniProtKB/Swiss-Prot:P39602" /translation="MYIIMGVFTTIVNIASFYILVEIMNVDYKAATVAAWILSVLFAY ITNKLYVFQQKTHDLQSLLKELTAFFSVRVLSLGIDLGMMIILVGQFNTNETLAKILD NAVIVVVNYVASKWLVFKKTKEEGV*" gene complement(3787489..3787872) /gene="ywcD" /locus_tag="BSU_38210" /old_locus_tag="BSU38210" CDS complement(3787890..3788561) /gene="slrC" /locus_tag="BSU_38220" /old_locus_tag="BSU38220" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:18647168" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 18647168; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator of slrA (biofilm formation)" /protein_id="NP_391701.2" /db_xref="EnsemblGenomes-Gn:BSU38220" /db_xref="EnsemblGenomes-Tr:CAB15848" /db_xref="GOA:P39601" /db_xref="InterPro:IPR001647" /db_xref="InterPro:IPR009057" /db_xref="InterPro:IPR036271" /db_xref="SubtiList:BG10579" /db_xref="UniProtKB/Swiss-Prot:P39601" /translation="MKKNKFQIKREATFESFIDAGVNLLIDRAYDPVSVEDISRAAGY SKGAFYVHFVSKDDFLLYLLEKRQMKKKIIIGYLDQMERESVKSLTLDEAAKHAAELL YSYYINKPSWDITSFAMNMPTYKVLKKCKAYVRLYELWVEENVLYIKWLKERKLIDAC IDPEYTAKIICAVLDGIIKQSYVLGQPATFRSFLDALSVFFTLDREHERPRILKSFSE SEEHQ*" gene complement(3787890..3788561) /gene="slrC" /locus_tag="BSU_38220" /old_locus_tag="BSU38220" promotor_-10 complement(3788583..3788602) /Source="Nicolas_upshift_promotors" /id="U3007" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.715284715284715" /psig="0.987012987012987" /xcortree=2081 /SigmaFactorBS="aaccgaatagcataaccgtttaaagaaataaATACcgctaaa gattgatcCGGTGTAAGATAAGGGTAATcattaccgccaggagaaaaatatgaaaaaa a" /listShort="ywcC, ywcD, galK, galT" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3788592) /Source="Nicolas_upshifts" /id="U3007" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.715284715284715" /psig="0.987012987012987" /xcortree=2081 /SigmaFactorBS="aaccgaatagcataaccgtttaaagaaataaATACcgctaaa gattgatcCGGTGTAAGATAAGGGTAATcattaccgccaggagaaaaatatgaaaaaa a" /listShort="ywcC, ywcD, galK, galT" /GFF_Attribute="listLong" promotor_-35 complement(3788618..3788621) /Source="Nicolas_upshift_promotors" /id="U3007" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.715284715284715" /psig="0.987012987012987" /xcortree=2081 /SigmaFactorBS="aaccgaatagcataaccgtttaaagaaataaATACcgctaaa gattgatcCGGTGTAAGATAAGGGTAATcattaccgccaggagaaaaatatgaaaaaa a" /listShort="ywcC, ywcD, galK, galT" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 3788702..3788705 /Source="Nicolas_upshift_promotors" /id="U3008" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.518481518481518" /psig="0.996003996003996" /xcortree=3106 /SigmaFactorBS="taataggctaaatgatttattttcatttacataCTATccagt cagtatttaATTGTTTATTATTATAAATAaggtccattggttatattagtcatttttt t" /listShort="S1474, slrA, S1475, ywcB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3788720..3788739 /Source="Nicolas_upshift_promotors" /id="U3008" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.518481518481518" /psig="0.996003996003996" /xcortree=3106 /SigmaFactorBS="taataggctaaatgatttattttcatttacataCTATccagt cagtatttaATTGTTTATTATTATAAATAaggtccattggttatattagtcatttttt t" /listShort="S1474, slrA, S1475, ywcB" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 3788729..3788916 /Source="Nicolas_S_feature" /locus_tag="new_3923131_3923318" /HighExp="T0.30H, T1.0H, Cold, T1.30H, HiOs, T-0.40H, T2.0H, T2.30H, T4.0H, BC" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.996" /TUlongSig="NA" /TUlongPSig="NA" /label="S1474" upshifts 3788729 /Source="Nicolas_upshifts" /id="U3008" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.518481518481518" /psig="0.996003996003996" /xcortree=3106 /SigmaFactorBS="taataggctaaatgatttattttcatttacataCTATccagt cagtatttaATTGTTTATTATTATAAATAaggtccattggttatattagtcatttttt t" /listShort="S1474, slrA, S1475, ywcB" /GFF_Attribute="listLong" CDS 3788917..3789075 /gene="slrA" /locus_tag="BSU_38229" /old_locus_tag="BSU38229" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:18647168, 26857544" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 18647168, 26857544; Product type r: regulator" /codon_start=1 /transl_table=11 /product="anti-repressor of SlrR" /protein_id="YP_003097794.1" /db_xref="EnsemblGenomes-Gn:BSU38229" /db_xref="EnsemblGenomes-Tr:CAX52707" /db_xref="GOA:P0C8M5" /db_xref="InterPro:IPR010981" /db_xref="InterPro:IPR036281" /db_xref="UniProtKB/Swiss-Prot:P0C8M5" /translation="MKTHVKKDLDKGWHMLIQEARSIGLGIHDVRQFLESETASRKKN HKKTVRQD*" gene 3788917..3789075 /gene="slrA" /locus_tag="BSU_38229" /old_locus_tag="BSU38229" S_feature 3789076..3789460 /Source="Nicolas_S_feature" /locus_tag="new_3923478_3923862" /HighExp="T0.30H, Cold, T1.30H, T2.0H, T1.0H, HiOs, T2.30H, T3.0H, LBGstat, C30" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.996" /TUlongSig="NA" /TUlongPSig="NA" /label="S1475" promotor_-35 3789441..3789446 /Source="Nicolas_upshift_promotors" /id="U3009" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1051 /SigmaFactorBS="acgacttccttcttttttcatcctccagctattgtacaaCGC ATAaatcggactttcagtACATACCTATTGGTGTACCtttttgcttacgtttagcgaa t" /listShort="ywcB, ywcA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3789462..3789480 /Source="Nicolas_upshift_promotors" /id="U3009" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1051 /SigmaFactorBS="acgacttccttcttttttcatcctccagctattgtacaaCGC ATAaatcggactttcagtACATACCTATTGGTGTACCtttttgcttacgtttagcgaa t" /listShort="ywcB, ywcA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3789462 /Source="Nicolas_upshifts" /id="U3009" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1051 /SigmaFactorBS="acgacttccttcttttttcatcctccagctattgtacaaCGC ATAaatcggactttcagtACATACCTATTGGTGTACCtttttgcttacgtttagcgaa t" /listShort="ywcB, ywcA" /GFF_Attribute="listLong" CDS 3789518..3789826 /gene="vbfB" /locus_tag="BSU_38230" /old_locus_tag="BSU38230" /function="16.1: Circulate" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:26060272, 28357266" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 26060272, 28357266; Product type t: transporter" /codon_start=1 /transl_table=11 /product="subunit of acetate transporter as a volatile signal for biofilm formation" /protein_id="NP_391702.1" /db_xref="EnsemblGenomes-Gn:BSU38230" /db_xref="EnsemblGenomes-Tr:CAB15849" /db_xref="GOA:P39600" /db_xref="InterPro:IPR007436" /db_xref="SubtiList:BG10578" /db_xref="UniProtKB/Swiss-Prot:P39600" /translation="MYKADYKQIAATPSFQAFLKQKRAFIVPSAIFFFVFYFSLPVLT SYFTFLNAPAIGAVSWAWLFAIAQFAMTWILSTVYSRRAAHFDKYVSALKEDLKGEQT *" gene 3789518..3789826 /gene="vbfB" /locus_tag="BSU_38230" /old_locus_tag="BSU38230" downshifts complement(3789604) /Source="Nicolas_upshifts" /id="D1978" /incds=1 /nref=3 /ntot=15 /MaxReadThrough="0.42282" /MaxDrop="5.4957" /score="10.1452497" /energy="-8.3" /TU="NA" /idTUdmin="U3010" /TUdmin=0 /isTUend="TRUE" promotor_no_box complement(3789608..3789708) /Source="Nicolas_upshift_promotors" /id="U3010" /multdbtbs="-" /comp="M21" /sig="Sig-" /pcomp="0.731268731268731" /psig="0.017982017982018" /xcortree=279 /SigmaFactorBS="aacagccaagcccatgaaacagctccaatggccggtgcattc aaaaaggtgaaataagatgtcaaaacagggagtgaaaaataaaaaacaaaaaagaaaa t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_no_box" upshifts complement(3789648) /Source="Nicolas_upshifts" /id="U3010" /multdbtbs="-" /comp="M21" /sig="Sig-" /pcomp="0.731268731268731" /psig="0.017982017982018" /xcortree=279 /SigmaFactorBS="aacagccaagcccatgaaacagctccaatggccggtgcattc aaaaaggtgaaataagatgtcaaaacagggagtgaaaaataaaaaacaaaaaagaaaa t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" CDS 3789823..3791364 /gene="vbfA" /locus_tag="BSU_38240" /old_locus_tag="BSU38240" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:15849754, 16850406, 26060272, 28357266" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15849754, 16850406, 26060272, 28357266; Product type t: transporter" /codon_start=1 /transl_table=11 /product="acetate Na+-dependent symporter subunit involvedin volatile signal for biofilm formation" /protein_id="NP_391703.2" /db_xref="EnsemblGenomes-Gn:BSU38240" /db_xref="EnsemblGenomes-Tr:CAB15850" /db_xref="GOA:P39599" /db_xref="InterPro:IPR001734" /db_xref="InterPro:IPR018212" /db_xref="SubtiList:BG10577" /db_xref="UniProtKB/Swiss-Prot:P39599" /translation="MNMTAFLLFLAIVGLTLIITYFAAKRTKTTSEFYTAGGGLTGVQ NGLAIAGDYMSAASFLGIAGMIALYGFDGFFYSIGFLVAYLVVLYIVAEPLRNLGKYT MADMIAARFKEKKIRGVAALNTIAISTFYMIAQLVGAGALIKLLLGLDYTAAVLIVGV LMTIYVVFGGMIATSWVQIIKAVLLMAGTLVISIIVFSKFGFSLNTMFEQMKTATPLG ADFLNPGNKYKVPLETLSLNLALVLGTAGLPHILIRFYTVKDAKTARTSVVSATWIIG VFYIMTVFLGFGAAAFVGFDAITAADQAGNMAAPLLAKALGGDFLFAFVSAIAFATIL AVVTGLVLSAASAFAHDIYSQIIRKGEATEKEQMKAARWASVAVSVLSILLAIFAQSL NVAFLVALAFAVAASANLPLIVFTVFWKRFNASGALWGSLTGLISALVLVSMSPSVWD PAGGAIFTGDPLIPLSNPGIISIPLGFLGAWLGTVLSSDKTIDEDTFAEIQVKAHTGV HMEQE*" gene 3789823..3791364 /gene="vbfA" /locus_tag="BSU_38240" /old_locus_tag="BSU38240" downshifts 3791355 /Source="Nicolas_upshifts" /id="D1979" /incds=0 /nref=4 /ntot=35 /MaxReadThrough="2.40129" /MaxDrop="4.15104" /score="2.66606932" /energy="-7.8" /TU="NA" /idTUdmin="U3009" /TUdmin=0 /isTUend="TRUE" CDS complement(3791395..3791997) /gene="ywbO" /locus_tag="BSU_38250" /old_locus_tag="BSU38250" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative sulfur oxido-reductase" /protein_id="NP_391704.1" /db_xref="EnsemblGenomes-Gn:BSU38250" /db_xref="EnsemblGenomes-Tr:CAB15851" /db_xref="GOA:P39598" /db_xref="InterPro:IPR001853" /db_xref="InterPro:IPR036249" /db_xref="SubtiList:BG10576" /db_xref="UniProtKB/Swiss-Prot:P39598" /translation="MTVHIKVYSDYVCPFCFVGKAAFEEAIKGKDVEVEWMPFELRPS PSPQLDPVNDPSKQYMWQTSIQPMAEKLGVEINFPNVSPHPYTDLAFEGFHFAKEYNK GHEYNTRVFQAFFQEDQNIGDIDILTKLAEEVGLDGASFKSALETRTYQDVQRQALKH AYEEADITAVPTFIIGDTVIPGAAGKDVFEKAISDEQKKK*" gene complement(3791395..3791997) /gene="ywbO" /locus_tag="BSU_38250" /old_locus_tag="BSU38250" downshifts complement(3791409) /Source="Nicolas_upshifts" /id="D1980" /incds=0 /nref=12 /ntot=123 /MaxReadThrough="1.89374" /MaxDrop="3.51247" /score="21.9354981" /energy="-7.8" /TU="NA" /idTUdmin="U3011" /TUdmin=0 /isTUend="TRUE" S_feature complement(3791998..3792279) /Source="Nicolas_S_feature" /locus_tag="new_3926400_3926681_c" /HighExp="T1.0H, G135, G150, T1.30H, Lbexp, G180, Lbstat, dia5, LBGexp, M0t45" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="0.984, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S1476" CDS complement(3792280..3793530) /gene="efeB" /locus_tag="BSU_38260" /old_locus_tag="BSU38260" /EC_number="1.11.1.-" /function="16.11: Scavenge (Catabolism)" /function="16.2: Construct biomass (Anabolism)" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:12354229, 15554971, 16672620, 16987175, 18931290, 19383693, 21479178, 23764491, 24620988, 27795321" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12354229, 15554971, 16672620, 16987175, 18931290, 19383693, 21479178, 23764491, 24620988, 27795321; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="peroxidase converting ferric iron into ferrous iron" /protein_id="NP_391705.1" /db_xref="EnsemblGenomes-Gn:BSU38260" /db_xref="EnsemblGenomes-Tr:CAB15852" /db_xref="GOA:P39597" /db_xref="InterPro:IPR006311" /db_xref="InterPro:IPR006313" /db_xref="InterPro:IPR006314" /db_xref="InterPro:IPR011008" /db_xref="InterPro:IPR019546" /db_xref="SubtiList:BG10575" /db_xref="UniProtKB/Swiss-Prot:P39597" /translation="MSDEQKKPEQIHRRDILKWGAMAGAAVAIGASGLGGLAPLVQTA AKPSKKDEKEEEQIVPFYGKHQAGITTAHQTYVYFAALDVTAKDKSDIITLFRNWTSL TQMLTSGKKMSAEQRNQYLPPQDTGESADLSPSNLTVTFGFGPGFFEKDGKDRFGLKS KKPKHLAALPAMPNDNLDEKQGGGDICIQVCADDEQVAFHALRNLLNQAVGTCEVRFV NKGFLSGGKNGETPRNLFGFKDGTGNQSTKDDTLMNSIVWIQSGEPDWMTGGTYMAFR KIKMFLEVWDRSSLKDQEDTFGRRKSSGAPFGQKKETDPVKLNQIPSNSHVSLAKSTG KQILRRAFSYTEGLDPKTGYMDAGLLFISFQKNPDNQFIPMLKALSAKDALNEYTQTI GSALYACPGGCKKGEYIAQRLLES*" gene complement(3792280..3793530) /gene="efeB" /locus_tag="BSU_38260" /old_locus_tag="BSU38260" downshifts complement(3792376) /Source="Nicolas_upshifts" /id="D1981" /incds=1 /nref=67 /ntot=232 /MaxReadThrough="5.0552" /MaxDrop="3.65898" /score="21.9354981" /energy="-7.8" /TU="U3011,U3012" /idTUdmin="U3011" /TUdmin="-967" /isTUend="FALSE" CDS complement(3793549..3794706) /gene="efeM" /locus_tag="BSU_38270" /old_locus_tag="BSU38270" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:12354229, 15849754, 16672620, 16850406, 16987175, 23764491, 27795321" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12354229, 15849754, 16672620, 16850406, 16987175, 23764491, 27795321; Product type t: transporter" /codon_start=1 /transl_table=11 /product="lipoprotein binding ferrous or ferric iron for transport" /protein_id="NP_391706.1" /db_xref="EnsemblGenomes-Gn:BSU38270" /db_xref="EnsemblGenomes-Tr:CAB15853" /db_xref="GOA:P39596" /db_xref="InterPro:IPR018976" /db_xref="InterPro:IPR034981" /db_xref="SubtiList:BG10574" /db_xref="UniProtKB/Swiss-Prot:P39596" /translation="MNFTKIAVSAGCILALCAGCGANDTSSTKEKASSEKSGVTKEIT ASVNKMETIISKLNDSVEKGDQKEIEKKGKELNSYWLSFENDIRSDYPFEYTEIEKHL QPIYTEAQKDKPDAGKIKTESESLKASLEDLTEAKKSGKKASDQLAKAADEYKGYVKE QSDQLVKATEAFTGAVKSGDIEKSKTLYAKARVYYERIEPIAESLGDLDPKIDAREND VEEGDKWTGFHKLEKAIWKDQDISGEKATADQLLKDVKELDGSIQSLKLTPEQIVAGA MELLNEAGISKITGEEERYSRIDLVDLMANVEGSEAVYQTVKSALVKDHSDLTEKLDT EFSEFEVLMAKYKTNDQSYTSYDKLSEKQIRELSTKLTTLSETMSKIANVL*" gene complement(3793549..3794706) /gene="efeM" /locus_tag="BSU_38270" /old_locus_tag="BSU38270" misc_feature complement(3793622..3793641) /Source="Nicolas_upshift_promotors" /id="U3011" /multdbtbs="SigW,SigX" /comp="M4" /sig="SigA" /pcomp="0.917082917082917" /psig="0.984015984015984" /xcortree=3235 /SigmaFactorBS="atacggagttcagcgaatttgaagttttaatggcaaaataca aaacaaatgatcagtcctatacgtctTATGATAAATTAAGTGAAAAgcaaatcagaga g" /listShort="efeN, S1476, ywbO" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(3793649) /Source="Nicolas_upshifts" /id="U3011" /multdbtbs="SigW,SigX" /comp="M4" /sig="SigA" /pcomp="0.917082917082917" /psig="0.984015984015984" /xcortree=3235 /SigmaFactorBS="atacggagttcagcgaatttgaagttttaatggcaaaataca aaacaaatgatcagtcctatacgtctTATGATAAATTAAGTGAAAAgcaaatcagaga g" /listShort="efeN, S1476, ywbO" /GFF_Attribute="listLong" CDS complement(3794703..3796148) /gene="efeU" /locus_tag="BSU_38280" /old_locus_tag="BSU38280" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:12354229, 15849754, 16672620, 16850406, 16987175, 23764491, 27795321" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12354229, 15849754, 16672620, 16850406, 16987175, 23764491, 27795321; Product type t: transporter" /codon_start=1 /transl_table=11 /product="ferrous ion permease" /protein_id="NP_391707.2" /db_xref="EnsemblGenomes-Gn:BSU38280" /db_xref="EnsemblGenomes-Tr:CAB15854" /db_xref="GOA:P39595" /db_xref="InterPro:IPR004923" /db_xref="SubtiList:BG10573" /db_xref="UniProtKB/Swiss-Prot:P39595" /translation="MARGLALILFSLLMVFGSAAHAEDDPIAALIQLNKQMIKSVKDG DMDSAQQTFDTFKAKWKKEEPSIKKENLSSHSEMDANIAMISLSFINQDARKLKTQLE ELASHLETYQQAVVLKKTSSGQSRASLTAYIQSLKDTKQFIEKKQLDEASSAIDNLVT SWLAVEGDVVSQSKEAYTTSEENLALMKAEIGSHPEKVSKQIDEMIQLLEPIASSSYS WWDAALIPVREGMEALLVIGALLTMTKKARVTRSSTWIWGGASAGMAVSLAAGIGVTV LFSSSVFGENNFLLGGVTGVLSAVMLLYVGVWLHRNASMDKWREKINIQKSQALKKRS LLSFALIAFLAVVREGLETVIFFIGLVGKLPLTELIGGTAAGLIVLVIVGVLMIKLGM RIPLKPFFLLSMAVVLYMCVKFLGTGVHSLQLAGILPSDAESWLPSVSVLGIYPSVYS TIPQMLILLFLLIALVSEAAKHFTNGKELTK*" gene complement(3794703..3796148) /gene="efeU" /locus_tag="BSU_38280" /old_locus_tag="BSU38280" promotor_-10 complement(3796182..3796201) /Source="Nicolas_upshift_promotors" /id="U3012" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.98901098901099" /psig=1 /xcortree=2103 /SigmaFactorBS="tccatcaaggttttcagaccttcaaattttAATTGACAaagg acaggaactGGCTATGATTATGTTATACAatgataatcattttcaattataggaggaa c" /listShort="efeU, efeM, efeN, S1476, ywbO" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3796192) /Source="Nicolas_upshifts" /id="U3012" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.98901098901099" /psig=1 /xcortree=2103 /SigmaFactorBS="tccatcaaggttttcagaccttcaaattttAATTGACAaagg acaggaactGGCTATGATTATGTTATACAatgataatcattttcaattataggaggaa c" /listShort="efeU, efeM, efeN, S1476, ywbO" /GFF_Attribute="listLong" promotor_-35 complement(3796215..3796222) /Source="Nicolas_upshift_promotors" /id="U3012" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.98901098901099" /psig=1 /xcortree=2103 /SigmaFactorBS="tccatcaaggttttcagaccttcaaattttAATTGACAaagg acaggaactGGCTATGATTATGTTATACAatgataatcattttcaattataggaggaa c" /listShort="efeU, efeM, efeN, S1476, ywbO" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3796305..3796973) /gene="thiE" /locus_tag="BSU_38290" /old_locus_tag="BSU38290" /EC_number="2.5.1.3" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 10382260, 16291685, 19888457, 22616866; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="thiamine-phosphate pyrophosphorylase (thiamine phosphate synthase)" /protein_id="NP_391708.1" /db_xref="EnsemblGenomes-Gn:BSU38290" /db_xref="EnsemblGenomes-Tr:CAB15855" /db_xref="GOA:P39594" /db_xref="InterPro:IPR013785" /db_xref="InterPro:IPR022998" /db_xref="InterPro:IPR034291" /db_xref="InterPro:IPR036206" /db_xref="PDB:1G4E" /db_xref="PDB:1G4P" /db_xref="PDB:1G4S" /db_xref="PDB:1G4T" /db_xref="PDB:1G67" /db_xref="PDB:1G69" /db_xref="PDB:1G6C" /db_xref="PDB:2TPS" /db_xref="PDB:3O15" /db_xref="PDB:3O16" /db_xref="SubtiList:BG10572" /db_xref="UniProtKB/Swiss-Prot:P39594" /translation="MTRISREMMKELLSVYFIMGSNNTKADPVTVVQKALKGGATLYQ FREKGGDALTGEARIKFAEKAQAACREAGVPFIVNDDVELALNLKADGIHIGQEDANA KEVRAAIGDMILGVSAHTMSEVKQAEEDGADYVGLGPIYPTETKKDTRAVQGVSLIEA VRRQGISIPIVGIGGITIDNAAPVIQAGADGVSMISAISQAEDPESAARKFREEIQTY KTGR*" gene complement(3796305..3796973) /gene="thiE" /locus_tag="BSU_38290" /old_locus_tag="BSU38290" downshifts complement(3796314) /Source="Nicolas_upshifts" /id="D1982" /incds=0 /nref=44 /ntot=194 /MaxReadThrough="1.62789" /MaxDrop="4.13196" /score="10.8502035" /energy="-10" /TU="NA" /idTUdmin="U3013" /TUdmin=0 /isTUend="TRUE" CDS complement(3796970..3797788) /gene="thiM" /locus_tag="BSU_38300" /old_locus_tag="BSU38300" /EC_number="2.7.1.50" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:10382260, 16291685, 22938038, 28729425" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10382260, 16291685, 22938038, 28729425; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="5-(2-hydroxyethyl)-4-methylthiazole kinase" /protein_id="NP_391709.1" /db_xref="EnsemblGenomes-Gn:BSU38300" /db_xref="EnsemblGenomes-Tr:CAB15856" /db_xref="GOA:P39593" /db_xref="InterPro:IPR000417" /db_xref="InterPro:IPR029056" /db_xref="PDB:1C3Q" /db_xref="PDB:1EKK" /db_xref="PDB:1EKQ" /db_xref="PDB:1ESJ" /db_xref="PDB:1ESQ" /db_xref="SubtiList:BG10571" /db_xref="UniProtKB/Swiss-Prot:P39593" /translation="MDAQSAAKCLTAVRRHSPLVHSITNNVVTNFTANGLLALGASPV MAYAKEEVADMAKIAGALVLNIGTLSKESVEAMIIAGKSANEHGVPVILDPVGAGATP FRTESARDIIREVRLAAIRGNAAEIAHTVGVTDWLIKGVDAGEGGGDIIRLAQQAAQK LNTVIAITGEVDVIADTSHVYTLHNGHKLLTKVTGAGCLLTSVVGAFCAVEENPLFAA IAAISSYGVAAQLAAQQTADKGPGSFQIELLNKLSTVTEQDVQEWATIERVTVS*" gene complement(3796970..3797788) /gene="thiM" /locus_tag="BSU_38300" /old_locus_tag="BSU38300" CDS complement(3797796..3798701) /gene="cidR" /locus_tag="BSU_38310" /old_locus_tag="BSU38310" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 23504016; Product type r : regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator (LysR family, cidAB expression)" /protein_id="NP_391710.1" /db_xref="EnsemblGenomes-Gn:BSU38310" /db_xref="EnsemblGenomes-Tr:CAB15857" /db_xref="GOA:P39592" /db_xref="InterPro:IPR000847" /db_xref="InterPro:IPR005119" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG10570" /db_xref="UniProtKB/Swiss-Prot:P39592" /translation="MDIRHLTYFLEVARLKSFTKASQSLYVSQPTISKMIKNLEEELG IELFYRNGRQVELTDAGHSMYVQAQEIIKSFQNLTSELNDIMEVKKGHVRIGLPPMIG SGFFPRVLGDFRENYPNVTFQLVEDGSIKVQEGVGDGSLDIGVVVLPANEDIFHSFTI VKETLMLVVHPSHRLADEKECQLRELKDEPFIFFREDFVLHNRIMTECIKAGFRPHII YETSQWDFISEMVSANLGIGLLPERICRGLDPEKVKVIPLVDPVIPWHLAIIWRKDRY LSFAARAWLEHTKSYLWDPKKDSKG*" gene complement(3797796..3798701) /gene="cidR" /locus_tag="BSU_38310" /old_locus_tag="BSU38310" misc_feature complement(3798436..3798455) /Source="Nicolas_upshift_promotors" /id="U3013" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.857142857142857" /psig="0.992007992007992" /xcortree=2665 /SigmaFactorBS="tgtgcaggcgcaggaaatcattaaatcatttcaaaacctgac gtcagaattaAATGATATTATGGAAGTCAAgaaagggcacgtacggattggactgccg c" /listShort="thiM, thiE" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(3798447) /Source="Nicolas_upshifts" /id="U3013" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.857142857142857" /psig="0.992007992007992" /xcortree=2665 /SigmaFactorBS="tgtgcaggcgcaggaaatcattaaatcatttcaaaacctgac gtcagaattaAATGATATTATGGAAGTCAAgaaagggcacgtacggattggactgccg c" /listShort="thiM, thiE" /GFF_Attribute="listLong" promotor_-10 complement(3798742..3798761) /Source="Nicolas_upshift_promotors" /id="U3014" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.531468531468531" /psig="0.996003996003996" /xcortree=2443 /SigmaFactorBS="agcaacagttttttcatattgatgcctcccttatatactTAT TGTACataaggtctctctatAGGTAAAATATATATTAAGAataagaagtattcctttt g" /listShort="ywbI, thiM, thiE" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 3798752..3798759 /Source="Nicolas_upshift_promotors" /id="U3015" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.845154845154845" /psig=1 /xcortree=2449 /SigmaFactorBS="cctttctatagacaaaaggaatacttcttattcttaatataT ATTTTACctatagagagaccTTATGTACAATAAGTATATAagggaggcatcaatatga a" /listShort="cidA, lrgB" /GFF_Attribute="listLong" /label="promotor_-35" upshifts complement(3798763) /Source="Nicolas_upshifts" /id="U3014" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.531468531468531" /psig="0.996003996003996" /xcortree=2443 /SigmaFactorBS="agcaacagttttttcatattgatgcctcccttatatactTAT TGTACataaggtctctctatAGGTAAAATATATATTAAGAataagaagtattcctttt g" /listShort="ywbI, thiM, thiE" /GFF_Attribute="listLong" upshifts 3798771 /Source="Nicolas_upshifts" /id="U3015" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.845154845154845" /psig=1 /xcortree=2449 /SigmaFactorBS="cctttctatagacaaaaggaatacttcttattcttaatataT ATTTTACctatagagagaccTTATGTACAATAAGTATATAagggaggcatcaatatga a" /listShort="cidA, lrgB" /GFF_Attribute="listLong" promotor_-10 3798773..3798792 /Source="Nicolas_upshift_promotors" /id="U3015" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.845154845154845" /psig=1 /xcortree=2449 /SigmaFactorBS="cctttctatagacaaaaggaatacttcttattcttaatataT ATTTTACctatagagagaccTTATGTACAATAAGTATATAagggaggcatcaatatga a" /listShort="cidA, lrgB" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 complement(3798777..3798784) /Source="Nicolas_upshift_promotors" /id="U3014" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.531468531468531" /psig="0.996003996003996" /xcortree=2443 /SigmaFactorBS="agcaacagttttttcatattgatgcctcccttatatactTAT TGTACataaggtctctctatAGGTAAAATATATATTAAGAataagaagtattcctttt g" /listShort="ywbI, thiM, thiE" /GFF_Attribute="listLong" /label="promotor_-35" CDS 3798807..3799193 /gene="cidA" /locus_tag="BSU_38320" /old_locus_tag="BSU38320" /function="16.13: Shape" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 15659658, 15849754, 16850406, 22383849, 26060272; Product type r: regulator" /codon_start=1 /transl_table=11 /product="metabolic regulator of murein hydrolases" /protein_id="NP_391711.1" /db_xref="EnsemblGenomes-Gn:BSU38320" /db_xref="EnsemblGenomes-Tr:CAB15858" /db_xref="GOA:P39591" /db_xref="InterPro:IPR005538" /db_xref="InterPro:IPR023760" /db_xref="SubtiList:BG10569" /db_xref="UniProtKB/Swiss-Prot:P39591" /translation="MKKLLLTVIQIALLFIFARLINWVTALLHINIPGSIIGIVILFT LLHFNIIKLEWIELGAAWLLGELLLFFIPSAVGVIEYGDIMSKFGVSILLVVIISTFV VMVSTGTLTQLIAKRKEKKHTCSSEL*" gene 3798807..3799193 /gene="cidA" /locus_tag="BSU_38320" /old_locus_tag="BSU38320" CDS 3799175..3799852 /gene="cidB" /locus_tag="BSU_38330" /old_locus_tag="BSU38330" /function="16.13: Shape" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 15659658, 15849754, 16850406, 26060272; Product type r: regulator" /codon_start=1 /transl_table=11 /product="metabolic regulator controlling activity of murein hydrolases" /protein_id="NP_391712.2" /db_xref="EnsemblGenomes-Gn:BSU38330" /db_xref="EnsemblGenomes-Tr:CAB15859" /db_xref="GOA:P39590" /db_xref="InterPro:IPR005261" /db_xref="InterPro:IPR007300" /db_xref="SubtiList:BG10568" /db_xref="UniProtKB/Swiss-Prot:P39590" /translation="MFIGIVSLFLTVLVYLGAKKVYQRFPRVYTSPLLVTPAVLVGLL LLVNVPYESYNLGGGLLTDMLQPATVAFAIPLYKYFPVLKKYAVEIILNVAVGSCIAI ISTALIAKWLHLGTGLIDSLVPRSVTTPIAMNVSEMIGGMPAVTAVFVILTALLGTVI GPMVIRYFRIDNEIARGVLLGTSAHGAGTSKAFELSSVSGTISSVSMILAAIMTLCAA PFLLSFM*" gene 3799175..3799852 /gene="cidB" /locus_tag="BSU_38330" /old_locus_tag="BSU38330" downshifts 3799824 /Source="Nicolas_upshifts" /id="D1983" /incds=0 /nref=13 /ntot=88 /MaxReadThrough="2.20109" /MaxDrop="4.23919" /score="27.0474383" /energy="-8" /TU="NA" /idTUdmin="U3015" /TUdmin=0 /isTUend="TRUE" promotor_-35 3799896..3799903 /Source="Nicolas_upshift_promotors" /id="U3016" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.91008991008991" /psig="0.999000999001" /xcortree=3230 /SigmaFactorBS="aaactgtcctctcgagggcagttttttttatgtgcttcccct TATTGAAAagctggcgaattcCAATATAATGTATTTGTGGAtaccaaaggaggcaccc t" /listShort="ywbF, ywbE" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 3799914 /Source="Nicolas_upshifts" /id="U3016" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.91008991008991" /psig="0.999000999001" /xcortree=3230 /SigmaFactorBS="aaactgtcctctcgagggcagttttttttatgtgcttcccct TATTGAAAagctggcgaattcCAATATAATGTATTTGTGGAtaccaaaggaggcaccc t" /listShort="ywbF, ywbE" /GFF_Attribute="listLong" promotor_-10 3799917..3799936 /Source="Nicolas_upshift_promotors" /id="U3016" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.91008991008991" /psig="0.999000999001" /xcortree=3230 /SigmaFactorBS="aaactgtcctctcgagggcagttttttttatgtgcttcccct TATTGAAAagctggcgaattcCAATATAATGTATTTGTGGAtaccaaaggaggcaccc t" /listShort="ywbF, ywbE" /GFF_Attribute="listLong" /label="promotor_-10" CDS 3799956..3801155 /gene="ywbF" /locus_tag="BSU_38340" /old_locus_tag="BSU38340" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative sugar permease" /protein_id="NP_391713.1" /db_xref="EnsemblGenomes-Gn:BSU38340" /db_xref="EnsemblGenomes-Tr:CAB15860" /db_xref="GOA:P39589" /db_xref="InterPro:IPR020846" /db_xref="InterPro:IPR024989" /db_xref="InterPro:IPR026032" /db_xref="InterPro:IPR036259" /db_xref="SubtiList:BG10567" /db_xref="UniProtKB/Swiss-Prot:P39589" /translation="MHNLQVRRHYAALKGFYLFAFLGTGSIIPLLSMYLTKEQHLSGS QVGLIMSLGPIVMIFFQPFWGMLSDYTQKTKGLLAVCTSITGIIGLAYIAFDSFPLFI LIAACFAAFQSTIIPLSDSISLRYTQETNGNYGGIRLFGSLGFGVAVFAMGQVTNQLY PIHVIFIFGCAFLCIAAILASQVPGQQKTTKVNIRKGFRELISNKTFLIFMIITFTTF APNLANNTYFSLFLDKSGASLSAIGILFFIGVISEIPFMRFAQTFIDKMGLLNVIMLS GGVSLFRWALYFTAPSLWIIYATVFLQGVAIGLFIPAALQYVKKITPRHVEATALTMY AAIGNGFGNWFCTFAGGYIFDYVSIFAVYLLFGILSIAGFGLTLYLMKAEKNKHTLHQ PAVTFKP*" gene 3799956..3801155 /gene="ywbF" /locus_tag="BSU_38340" /old_locus_tag="BSU38340" CDS 3801189..3801386 /gene="ywbE" /locus_tag="BSU_38350" /old_locus_tag="BSU38350" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_391714.1" /db_xref="EnsemblGenomes-Gn:BSU38350" /db_xref="EnsemblGenomes-Tr:CAB15861" /db_xref="InterPro:IPR019240" /db_xref="SubtiList:BG10566" /db_xref="UniProtKB/Swiss-Prot:P39588" /translation="MNGQERNSISKGLQVDIVLKADQKTGKLTRGTVKDILTKSNFHP HGIKVRLEDGRIGRDQQIVST*" gene 3801189..3801386 /gene="ywbE" /locus_tag="BSU_38350" /old_locus_tag="BSU38350" downshifts 3801365 /Source="Nicolas_upshifts" /id="D1984" /incds=0 /nref=15 /ntot=205 /MaxReadThrough="1.90583" /MaxDrop="4.20528" /score="21.8132292" /energy="-12.2" /TU="NA" /idTUdmin="U3016" /TUdmin=88 /isTUend="FALSE" CDS complement(3801422..3802612) /gene="rlmI" /locus_tag="BSU_38360" /old_locus_tag="BSU38360" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 18786544, 18789337; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="large subunit ribosomal RNA m5C1962 methyltransferase" /protein_id="NP_391715.1" /db_xref="EnsemblGenomes-Gn:BSU38360" /db_xref="EnsemblGenomes-Tr:CAB15862" /db_xref="GOA:P39587" /db_xref="InterPro:IPR002478" /db_xref="InterPro:IPR015947" /db_xref="InterPro:IPR019614" /db_xref="InterPro:IPR029063" /db_xref="InterPro:IPR036974" /db_xref="SubtiList:BG10565" /db_xref="UniProtKB/Swiss-Prot:P39587" /translation="MKLLTLKKAHAAKIKKGYPLIEKEALAGSAGHMKEGDLVDIVSE SGGEFLARGYYGLQNKGVGWTLTRNKHEQIDQAFFLSKLTKAAQARAKLFEAQDTTAF RLFNGEGDGVGGVTIDYYDGYLLIQWYSKGIYTFKDMLISALDEMDLDYKAIYEKKRF DTAGQYVEDDDFVKGRRGEFPIIIQENGIQYAVDLNEGAMTGIFLDQRHVRKAIRDRY AKGKTVLNTFSYTGAFSVAAALGGAEKTTSVDVANRSLAKTIEQFSVNKLDYEAHDIK VMDVFNYFSYAAKKDLRFDLIILDPPSFARTKKRTFSAAKDYKNLLKETIAITADKGV IVASTNSSAFGMKKFKGFIDAAFKETNERYTIIEEFTLPEDFKTISAFPEGNYLKVVL LQKK*" gene complement(3801422..3802612) /gene="rlmI" /locus_tag="BSU_38360" /old_locus_tag="BSU38360" downshifts complement(3801437) /Source="Nicolas_upshifts" /id="D1985" /incds=0 /nref=5 /ntot=127 /MaxReadThrough="0.0525399999999996" /MaxDrop="4.51664" /score="48.4884619" /energy="-14.3" /TU="NA" /idTUdmin="U3017" /TUdmin=71 /isTUend="FALSE" downshifts complement(3801521) /Source="Nicolas_upshifts" /id="D1986" /incds=1 /nref=42 /ntot=233 /MaxReadThrough="2.99734" /MaxDrop="3.89369" /score="48.4884619" /energy="-14.3" /TU="NA" /idTUdmin="U3017" /TUdmin="-13" /isTUend="TRUE" misc_feature complement(3802636..3802655) /Source="Nicolas_upshift_promotors" /id="U3017" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.738261738261738" /psig=1 /xcortree=1883 /SigmaFactorBS="tttttgtctatcgtagaaaaacctttcctttctgtcaatgca gacatcttggcgtttTGTGGTACCATAAGAGAAAGcaaacggaaagaggacgacatat a" /listShort="ywbD" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(3802652) /Source="Nicolas_upshifts" /id="U3017" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.738261738261738" /psig=1 /xcortree=1883 /SigmaFactorBS="tttttgtctatcgtagaaaaacctttcctttctgtcaatgca gacatcttggcgtttTGTGGTACCATAAGAGAAAGcaaacggaaagaggacgacatat a" /listShort="ywbD" /GFF_Attribute="listLong" promotor_-35 3802672..3802679 /Source="Nicolas_upshift_promotors" /id="U3018" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.517482517482518" /psig=1 /xcortree=1984 /SigmaFactorBS="tccgtttgctttctcttatggtaccacaaaacgccaagatgt ctGCATTGACagaaaggaaaggtTTTTCTACGATAGACAAAAAgagttacgaggagga g" /listShort="ywbC" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 3802688 /Source="Nicolas_upshifts" /id="U3018" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.517482517482518" /psig=1 /xcortree=1984 /SigmaFactorBS="tccgtttgctttctcttatggtaccacaaaacgccaagatgt ctGCATTGACagaaaggaaaggtTTTTCTACGATAGACAAAAAgagttacgaggagga g" /listShort="ywbC" /GFF_Attribute="listLong" promotor_-10 3802693..3802712 /Source="Nicolas_upshift_promotors" /id="U3018" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.517482517482518" /psig=1 /xcortree=1984 /SigmaFactorBS="tccgtttgctttctcttatggtaccacaaaacgccaagatgt ctGCATTGACagaaaggaaaggtTTTTCTACGATAGACAAAAAgagttacgaggagga g" /listShort="ywbC" /GFF_Attribute="listLong" /label="promotor_-10" CDS 3802733..3803113 /gene="glxA" /locus_tag="BSU_38370" /old_locus_tag="BSU38370" /function="16.8: Protect" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:24330391, 25283443" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 24330391, 25283443; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="glyoxalase I; hemithioacetal-bacillithiol lactoyl-bacillithiol formation" /protein_id="NP_391716.1" /db_xref="EnsemblGenomes-Gn:BSU38370" /db_xref="EnsemblGenomes-Tr:CAB15863" /db_xref="GOA:P39586" /db_xref="InterPro:IPR004360" /db_xref="InterPro:IPR018146" /db_xref="InterPro:IPR029068" /db_xref="SubtiList:BG10564" /db_xref="UniProtKB/Swiss-Prot:P39586" /translation="MAKRIDHTGIMVRDINASITFYEEVLGMKLKDRITHTNGVIELA FLGFEDGPETEIELIQGYSSELPAEGKVHHIALLTDDIAAEYTKAEKMNAKFIDEEIT TLPNGYRYFYIEGPDGEWIEFFQR*" gene 3802733..3803113 /gene="glxA" /locus_tag="BSU_38370" /old_locus_tag="BSU38370" downshifts 3803011 /Source="Nicolas_upshifts" /id="D1987" /incds=1 /nref=14 /ntot=215 /MaxReadThrough="3.76076" /MaxDrop="3.68951" /score="-8.22053631" /energy="-7.4" /TU="U3018" /idTUdmin="U3018" /TUdmin="-357" /isTUend="FALSE" downshifts 3803082 /Source="Nicolas_upshifts" /id="D1988" /incds=0 /nref=1 /ntot=66 /MaxReadThrough="3.05249" /MaxDrop="3.56101" /score="-8.22053631" /energy="-7.4" /TU="U3018" /idTUdmin="U3018" /TUdmin="-286" /isTUend="FALSE" CDS complement(3803151..3803828) /gene="ywbB" /locus_tag="BSU_38380" /old_locus_tag="BSU38380" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_391717.1" /db_xref="EnsemblGenomes-Gn:BSU38380" /db_xref="EnsemblGenomes-Tr:CAB15864" /db_xref="InterPro:IPR024250" /db_xref="SubtiList:BG10563" /db_xref="UniProtKB/Swiss-Prot:P39585" /translation="MLDYIWLDDESPILQQVPVEYSSAALIFSPFIQMPEGWENAKRK NDYEHIYPNDNEIRGIGKAVSWKKVMSSCGFQTHAELALALMTSIGALRDEFAREDLA EVLHENINGDLYYPSEDHISNFHIPSLVKVLGANGSNRFYYAEPIVENRGVLDITEAN LRTVLDEAATELVLTDEKMDFVFMSVYDSFINVFLAKDKNIHELVERMGWEAMICDES TYISWYR*" gene complement(3803151..3803828) /gene="ywbB" /locus_tag="BSU_38380" /old_locus_tag="BSU38380" downshifts complement(3803158) /Source="Nicolas_upshifts" /id="D1989" /incds=0 /nref=6 /ntot=156 /MaxReadThrough="0.15283" /MaxDrop="5.41362" /score="0.491291944" /energy="-11.7" /TU="NA" /idTUdmin="U3020" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(3803837..3803856) /Source="Nicolas_upshift_promotors" /id="U3019" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.99100899100899" /psig="0.997002997002997" /xcortree=2178 /SigmaFactorBS="gataaaaatgtgatgtgatagatgatcagcctgtcatagggc tgatcaTCTCTTTcaaacgaaaggAATGTTAGAATATGTAAAGGaggtgcgcatgcta g" /listShort="ywbB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3803862) /Source="Nicolas_upshifts" /id="U3019" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.99100899100899" /psig="0.997002997002997" /xcortree=2178 /SigmaFactorBS="gataaaaatgtgatgtgatagatgatcagcctgtcatagggc tgatcaTCTCTTTcaaacgaaaggAATGTTAGAATATGTAAAGGaggtgcgcatgcta g" /listShort="ywbB" /GFF_Attribute="listLong" promotor_-35 complement(3803868..3803874) /Source="Nicolas_upshift_promotors" /id="U3019" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.99100899100899" /psig="0.997002997002997" /xcortree=2178 /SigmaFactorBS="gataaaaatgtgatgtgatagatgatcagcctgtcatagggc tgatcaTCTCTTTcaaacgaaaggAATGTTAGAATATGTAAAGGaggtgcgcatgcta g" /listShort="ywbB" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3803905..3805239) /gene="ywbA" /locus_tag="BSU_38390" /old_locus_tag="BSU38390" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 8990303, 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative cellobiose phosphotransferase system enzyme IIC permease component" /protein_id="NP_391718.1" /db_xref="EnsemblGenomes-Gn:BSU38390" /db_xref="EnsemblGenomes-Tr:CAB15865" /db_xref="GOA:P39584" /db_xref="InterPro:IPR003352" /db_xref="InterPro:IPR004501" /db_xref="InterPro:IPR004796" /db_xref="SubtiList:BG10562" /db_xref="UniProtKB/Swiss-Prot:P39584" /translation="MSTFTRVMEEKIMPVAGKIAGQRHLSALRDGIILTMPLIIIGSV FLILTSLPIPGYADFMASVFGNEWADKLGYPVNASFDIMAMIAAFGIAYRLAESYGVD ALSAGAISIAAFLLATPFEVPFTPHGSTESIMVGGGIPITLLGSKGLFVAMLIALFST EIYRYIIQKNIVFKMPDGVPPAVSKSFVALIPGFIIVLLVWLARLLIEMTPFQSLHNV VGDLLGTPLSILGGSLGGSLIAEFVQMLLWSCGIHGASIIGGIMAPIWYGAMDANRLA FQAGEALPSIFTTQFFQIWINVGGSGATLALVLTMLVRSRSKQMKQLGRLGIGPALFN INEPIIFGMPIVMNPLLIVPFIIAPLLTITATYIGMSTGLVARPAGIAVPWTMPPLIS GYLATGGKVSGAVMQLVNLLITCAIYYPFFRIWDHQKWREESAVESGDKNVM*" gene complement(3803905..3805239) /gene="ywbA" /locus_tag="BSU_38390" /old_locus_tag="BSU38390" misc_feature complement(3805287..3805305) /Source="Nicolas_upshift_promotors" /id="U3020" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.596403596403596" /psig="0.596403596403596" /xcortree=1254 /SigmaFactorBS="tttagcaaaatgcagattttttccgcatgaagaggaaatttt ccaaatgaatttgtaagcgttttCAAAATAAGATAAAGAAAAcattgcggaggttgtt c" /listShort="ywbA, ywbB" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(3805310) /Source="Nicolas_upshifts" /id="U3020" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.596403596403596" /psig="0.596403596403596" /xcortree=1254 /SigmaFactorBS="tttagcaaaatgcagattttttccgcatgaagaggaaatttt ccaaatgaatttgtaagcgttttCAAAATAAGATAAAGAAAAcattgcggaggttgtt c" /listShort="ywbA, ywbB" /GFF_Attribute="listLong" promotor_-35 3805404..3805411 /Source="Nicolas_upshift_promotors" /id="U3021" /multdbtbs="SigD" /comp="M10" /sig="SigD" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=2809 /SigmaFactorBS="ctgcattttgctaaacaaccctgcccatgaaaaattttttcc ttcttaCTATTAATctctctttttttcTCCGATATATATATCAAACatcatagaaaaa g" /listShort="epr" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 3805416 /Source="Nicolas_upshifts" /id="U3021" /multdbtbs="SigD" /comp="M10" /sig="SigD" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=2809 /SigmaFactorBS="ctgcattttgctaaacaaccctgcccatgaaaaattttttcc ttcttaCTATTAATctctctttttttcTCCGATATATATATCAAACatcatagaaaaa g" /listShort="epr" /GFF_Attribute="listLong" promotor_-10 3805425..3805443 /Source="Nicolas_upshift_promotors" /id="U3021" /multdbtbs="SigD" /comp="M10" /sig="SigD" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=2809 /SigmaFactorBS="ctgcattttgctaaacaaccctgcccatgaaaaattttttcc ttcttaCTATTAATctctctttttttcTCCGATATATATATCAAACatcatagaaaaa g" /listShort="epr" /GFF_Attribute="listLong" /label="promotor_-10" CDS 3805467..3807404 /gene="epr" /locus_tag="BSU_38400" /old_locus_tag="BSU38400" /EC_number="3.4.21.-" /function="16.11: Scavenge (Catabolism)" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:1938892, 2116590, 16553828, 17666034, 19416356, 23660663, 25966269" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1938892, 2116590, 16553828, 17666034, 19416356, 23660663, 25966269; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="extracellular serine protease" /protein_id="NP_391719.1" /db_xref="EnsemblGenomes-Gn:BSU38400" /db_xref="EnsemblGenomes-Tr:CAB15866" /db_xref="GOA:P16396" /db_xref="InterPro:IPR000209" /db_xref="InterPro:IPR009020" /db_xref="InterPro:IPR015500" /db_xref="InterPro:IPR022398" /db_xref="InterPro:IPR023827" /db_xref="InterPro:IPR023828" /db_xref="InterPro:IPR034202" /db_xref="InterPro:IPR036852" /db_xref="InterPro:IPR037045" /db_xref="SubtiList:BG10561" /db_xref="UniProtKB/Swiss-Prot:P16396" /translation="MKNMSCKLVVSVTLFFSFLTIGPLAHAQNSSEKEVIVVYKNKAG KETILDSDADVEQQYKHLPAVAVTADQETVKELKQDPDILYVENNVSFTAADSTDFKV LSDGTDTSDNFEQWNLEPIQVKQAWKAGLTGKNIKIAVIDSGISPHDDLSIAGGYSAV SYTSSYKDDNGHGTHVAGIIGAKHNGYGIDGIAPEAQIYAVKALDQNGSGDLQSLLQG IDWSIANRMDIVNMSLGTTSDSKILHDAVNKAYEQGVLLVAASGNDGNGKPVNYPAAY SSVVAVSATNEKNQLASFSTTGDEVEFSAPGTNITSTYLNQYYATGSGTSQATPHAAA MFALLKQRDPAETNVQLREEMRKNIVDLGTAGRDQQFGYGLIQYKAQATDSAYAAAEQ AVKKAEQTKAQIDINKARELISQLPNSDAKTALHKRLDKVQSYRNVKDAKDKVAKAEK YKTQQTVDTAQTAINKLPNGTDKKNLQKRLDQVKRYIASKQAKDKVAKAEKSKKKTDV DSAQSAIGKLPASSEKTSLQKRLNKVKSTNLKTAQQSVSAAEKKSTDANAAKAQSAVN QLQAGKDKTALQKRLDKVKKKVAAAEAKKVETAKAKVKKAEKDKTKKSKTSAQSAVNQ LKASNEKTKLQKRLNAVKPKK*" gene 3805467..3807404 /gene="epr" /locus_tag="BSU_38400" /old_locus_tag="BSU38400" promotor_-10 complement(3806611..3806630) /Source="Nicolas_upshift_promotors" /id="U3022" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.81018981018981" /psig="0.81018981018981" /xcortree=1236 /SigmaFactorBS="tgcttttgtttgttccgcttTTTTCACCGcttgctctgctgc CGCGTACGCTGAATCTGTTGcctgtgctttatactggattaagccgtagccaaattgc t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3806612) /Source="Nicolas_upshifts" /id="U3022" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.81018981018981" /psig="0.81018981018981" /xcortree=1236 /SigmaFactorBS="tgcttttgtttgttccgcttTTTTCACCGcttgctctgctgc CGCGTACGCTGAATCTGTTGcctgtgctttatactggattaagccgtagccaaattgc t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(3806644..3806652) /Source="Nicolas_upshift_promotors" /id="U3022" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.81018981018981" /psig="0.81018981018981" /xcortree=1236 /SigmaFactorBS="tgcttttgtttgttccgcttTTTTCACCGcttgctctgctgc CGCGTACGCTGAATCTGTTGcctgtgctttatactggattaagccgtagccaaattgc t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 3807394 /Source="Nicolas_upshifts" /id="D1990" /incds=0 /nref=175 /ntot=224 /MaxReadThrough="1.26567" /MaxDrop="6.00181" /score="15.6173594" /energy="-13" /TU="NA" /idTUdmin="U3021" /TUdmin=0 /isTUend="TRUE" promotor_-35 3807507..3807514 /Source="Nicolas_upshift_promotors" /id="U3023" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.813186813186813" /psig="0.99000999000999" /xcortree=1754 /SigmaFactorBS="ttgtacaggcttttcatacTATTGCTAtacagccatgaacaG CATAAAATGAACGTTATTAcagttatcaccacatatggcgggattgtgactgggcagg c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3807529..3807548 /Source="Nicolas_upshift_promotors" /id="U3023" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.813186813186813" /psig="0.99000999000999" /xcortree=1754 /SigmaFactorBS="ttgtacaggcttttcatacTATTGCTAtacagccatgaacaG CATAAAATGAACGTTATTAcagttatcaccacatatggcgggattgtgactgggcagg c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3807548 /Source="Nicolas_upshifts" /id="U3023" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.813186813186813" /psig="0.99000999000999" /xcortree=1754 /SigmaFactorBS="ttgtacaggcttttcatacTATTGCTAtacagccatgaacaG CATAAAATGAACGTTATTAcagttatcaccacatatggcgggattgtgactgggcagg c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 3807760..3807767 /Source="Nicolas_upshift_promotors" /id="U3024" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.447552447552448" /psig="0.996003996003996" /xcortree=2192 /SigmaFactorBS="catttttgtcattttcagccggtatttctcacttttttcaTT TTGATTgtcaacttttcaTTTGATACGATGAACAAGCCgacttttcttcagcaaagga g" /listShort="sacX, sacY" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3807780..3807799 /Source="Nicolas_upshift_promotors" /id="U3024" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.447552447552448" /psig="0.996003996003996" /xcortree=2192 /SigmaFactorBS="catttttgtcattttcagccggtatttctcacttttttcaTT TTGATTgtcaacttttcaTTTGATACGATGAACAAGCCgacttttcttcagcaaagga g" /listShort="sacX, sacY" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3807780 /Source="Nicolas_upshifts" /id="U3024" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.447552447552448" /psig="0.996003996003996" /xcortree=2192 /SigmaFactorBS="catttttgtcattttcagccggtatttctcacttttttcaTT TTGATTgtcaacttttcaTTTGATACGATGAACAAGCCgacttttcttcagcaaagga g" /listShort="sacX, sacY" /GFF_Attribute="listLong" CDS 3807832..3809211 /gene="sacX" /locus_tag="BSU_38410" /old_locus_tag="BSU38410" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:11580842, 1400159, 8535520, 15849754, 16850406" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11580842, 1400159, 8535520, 15849754, 16850406; Product type r: regulator" /codon_start=1 /transl_table=11 /product="negative regulator of SacY" /protein_id="NP_391720.1" /db_xref="EnsemblGenomes-Gn:BSU38410" /db_xref="EnsemblGenomes-Tr:CAB15867" /db_xref="GOA:P15400" /db_xref="InterPro:IPR001996" /db_xref="InterPro:IPR003352" /db_xref="InterPro:IPR010973" /db_xref="InterPro:IPR013013" /db_xref="InterPro:IPR018113" /db_xref="InterPro:IPR036878" /db_xref="SubtiList:BG10560" /db_xref="UniProtKB/Swiss-Prot:P15400" /translation="MHKEIAKELLLLAGGKNNIISISHCTTRLRFDVKDETKIDIHAI ENLQGVQGTFFRYGLFQIIFGAGVVNKIYKEVVHVWETAPSEEPVHQKKASRKLNPAA AFAKTLSDIFVPIIPAITASGLLMGLIGMIKVFHWFAAGSPWIKMLDLVSSTAFILLP ILVGFSAARQFGSNPYLGAVIAGLLTHPDLLDPSMLGSKTPSSLDIWGLHIPMMGYQG SMIPILLSVFVMSKIEKLLKSIVPKSLDVVIIPFITVMVTGCLALIVMNPAASIIGQI MTQSIVYIYDHAGIAAGALFGGIYSTIVLSGLHHSFYAIEATLLANPHVGVNFLVPIW SMANVAQGGAGLAVFLKTKQSSLKKIALPASLTAFLGIVEPIVFGVNLKLIRPFIGAA IGGAIGGAYVVAVQVVANSYGLTGIPMISIVLPFGAANFVHYMIGFLIAAVSAFIATL FLGFKEETE*" gene 3807832..3809211 /gene="sacX" /locus_tag="BSU_38410" /old_locus_tag="BSU38410" S_feature complement(3808920..3810123) /Source="Nicolas_S_feature" /locus_tag="new_3943322_3944525_c" /HighExp="Etha, B36, B60, M9-stat, Salt, Sw, LoTm, C30, Gly, Heat" /AntisenseName="sacY" /AntisenseCor="-0.177403958488455" /AntisenseRegPval="-2.5" /CDS_PredictionProba="NA" /TUshortSig="SigB" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1477" CDS 3809265..3810107 /gene="sacY" /locus_tag="BSU_38420" /old_locus_tag="BSU38420" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:9305644, 9457872, 11580842, 12079345, 15528654, 21278164" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9305644, 9457872, 11580842, 12079345, 15528654, 21278164; Product type r : regulator" /codon_start=1 /transl_table=11 /product="transcriptional antiterminator" /protein_id="NP_391721.1" /db_xref="EnsemblGenomes-Gn:BSU38420" /db_xref="EnsemblGenomes-Tr:CAB15868" /db_xref="GOA:P15401" /db_xref="InterPro:IPR001550" /db_xref="InterPro:IPR004341" /db_xref="InterPro:IPR011608" /db_xref="InterPro:IPR036634" /db_xref="InterPro:IPR036650" /db_xref="PDB:1AUU" /db_xref="SubtiList:BG10559" /db_xref="UniProtKB/Swiss-Prot:P15401" /translation="MKIKRILNHNAIVVKDQNEEKILLGAGIAFNKKKNDIVDPSKIE KTFIRKDTPDYKQFEEILETLPEDHIQISEQIISHAEKELNIKINERIHVAFSDHLSF AIERLSNGMVIKNPLLNEIKVLYPKEFQIGLWARALIKDKLGIHIPDDEIGNIAMHIH TARNNAGDMTQTLDITTMIRDIIEIIEIQLSINIVEDTISYERLVTHLRFAIQHIKAG ESIYELDAEMIDIIKEKFKDAFLCALSIGTFVKKEYGFEFPEKELCYIAMHIQRFYQR SVAR*" gene 3809265..3810107 /gene="sacY" /locus_tag="BSU_38420" /old_locus_tag="BSU38420" CDS complement(3810158..3811018) /gene="gspA" /locus_tag="BSU_38430" /old_locus_tag="BSU38430" /function="16.8: Protect" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 11377871, 19659723; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative glycosyl transferase (general stress protein)" /protein_id="NP_391722.1" /db_xref="EnsemblGenomes-Gn:BSU38430" /db_xref="EnsemblGenomes-Tr:CAB15869" /db_xref="GOA:P25148" /db_xref="InterPro:IPR002495" /db_xref="InterPro:IPR029044" /db_xref="SubtiList:BG10558" /db_xref="UniProtKB/Swiss-Prot:P25148" /translation="MRKDEIMHIVSCADDNYARHLGGMFVSLLTNMDQEREVKLYVID GGIKPDNKKRLEETTLKFGVPIEFLEVDTNMYEHAVESSHITKAAYYRISIPDLIKDE SIKRMIYIDCDALVLEDISKLWDLDIAPYTVAAVEDAGQHERLKEMNVTDTGKYFNSG IMIIDFESWRKQNITEKVINFINEHPDEDFLVLHDQDALNAILYDQWYELHPRWNAQT YIMLKLKTPSTLLGRKQYNETRENPAIVHFCGGEKPWNSNTKHPYRDEYFHYMSYTKW NTIGNPAINQ*" gene complement(3810158..3811018) /gene="gspA" /locus_tag="BSU_38430" /old_locus_tag="BSU38430" downshifts complement(3810168) /Source="Nicolas_upshifts" /id="D1991" /incds=0 /nref=73 /ntot=227 /MaxReadThrough="5.61926" /MaxDrop="7.47527" /score="21.8603429" /energy="-10.6" /TU="U3025" /idTUdmin="U3025" /TUdmin="-1224" /isTUend="FALSE" downshifts 3811002 /Source="Nicolas_upshifts" /id="D1992" /incds=0 /nref=8 /ntot=30 /MaxReadThrough="1.49599" /MaxDrop="5.33818" /score="10.6843241" /energy="-4.5" /TU="NA" /idTUdmin="U3026" /TUdmin="-528" /isTUend="FALSE" promotor_-10 complement(3811040..3811058) /Source="Nicolas_upshift_promotors" /id="U3025" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=226 /SigmaFactorBS="tgttgtatcacacattctgtttaaaaaaatgtcggagaaCGT GTTTatttttttgaaaaaGGGTATGTAACTTGTACAAcaaaaagggagatgaatacca t" /listShort="gspA, S1477" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3811058) /Source="Nicolas_upshifts" /id="U3025" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=226 /SigmaFactorBS="tgttgtatcacacattctgtttaaaaaaatgtcggagaaCGT GTTTatttttttgaaaaaGGGTATGTAACTTGTACAAcaaaaagggagatgaatacca t" /listShort="gspA, S1477" /GFF_Attribute="listLong" promotor_-35 complement(3811073..3811079) /Source="Nicolas_upshift_promotors" /id="U3025" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=226 /SigmaFactorBS="tgttgtatcacacattctgtttaaaaaaatgtcggagaaCGT GTTTatttttttgaaaaaGGGTATGTAACTTGTACAAcaaaaagggagatgaatacca t" /listShort="gspA, S1477" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3811128..3811841) /gene="ywaF" /locus_tag="BSU_38440" /old_locus_tag="BSU38440" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative integral membrane protein of unknown function" /protein_id="NP_391723.1" /db_xref="EnsemblGenomes-Gn:BSU38440" /db_xref="EnsemblGenomes-Tr:CAB15870" /db_xref="GOA:P25149" /db_xref="InterPro:IPR011737" /db_xref="SubtiList:BG10557" /db_xref="UniProtKB/Swiss-Prot:P25149" /translation="MQKYVQSDYKHDPFHLFSTEHVVTLAIISLLAILLFLFQDEVKQ PRASRFLRSLFVFLLLGSQIGYQIWMVATDRWSVRTSLPLQLSDLSVYLSAIMLVTKS RKLFVFLFFVGIGSSIQALATPDLGMFSFPHIRYILFFISHGSVFLSCLLMAVIGTYR MGQRSLWVTVLLVNVYGVCIFLIDRWLGANYMYLTKKPGGSSLLDVLGPWPWYIVSAE AITIASFFILYWLYRIFKK*" gene complement(3811128..3811841) /gene="ywaF" /locus_tag="BSU_38440" /old_locus_tag="BSU38440" promotor_-35 3811243..3811244 /Source="Nicolas_upshift_promotors" /id="U3026" /multdbtbs="-" /comp="M5" /sig="Sig-" /pcomp="0.275724275724276" /psig="0.275724275724276" /xcortree=93 /SigmaFactorBS="ccacggccatggcccgagaacatctaagagagaggaaCCgcc cggttttttcgtcaaaTACATATAATTCGCGCCAagccagcgatcaatcagaaaaata c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3811264..3811281 /Source="Nicolas_upshift_promotors" /id="U3026" /multdbtbs="-" /comp="M5" /sig="Sig-" /pcomp="0.275724275724276" /psig="0.275724275724276" /xcortree=93 /SigmaFactorBS="ccacggccatggcccgagaacatctaagagagaggaaCCgcc cggttttttcgtcaaaTACATATAATTCGCGCCAagccagcgatcaatcagaaaaata c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3811266 /Source="Nicolas_upshifts" /id="U3026" /multdbtbs="-" /comp="M5" /sig="Sig-" /pcomp="0.275724275724276" /psig="0.275724275724276" /xcortree=93 /SigmaFactorBS="ccacggccatggcccgagaacatctaagagagaggaaCCgcc cggttttttcgtcaaaTACATATAATTCGCGCCAagccagcgatcaatcagaaaaata c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 complement(3811869..3811880) /Source="Nicolas_upshift_promotors" /id="U3027" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.995004995004995" /psig="0.995004995004995" /xcortree=818 /SigmaFactorBS="ggtgtgaacttcaagcccatatatcggttGAATAAAaaaagc ccaaacaaCGCCAAAATAAAcaaaaacccgaaaacgggggtgcagttttgcaaaaata t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3811870) /Source="Nicolas_upshifts" /id="U3027" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.995004995004995" /psig="0.995004995004995" /xcortree=818 /SigmaFactorBS="ggtgtgaacttcaagcccatatatcggttGAATAAAaaaagc ccaaacaaCGCCAAAATAAAcaaaaacccgaaaacgggggtgcagttttgcaaaaata t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(3811895..3811901) /Source="Nicolas_upshift_promotors" /id="U3027" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.995004995004995" /psig="0.995004995004995" /xcortree=818 /SigmaFactorBS="ggtgtgaacttcaagcccatatatcggttGAATAAAaaaagc ccaaacaaCGCCAAAATAAAcaaaaacccgaaaacgggggtgcagttttgcaaaaata t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 3811916..3811922 /Source="Nicolas_upshift_promotors" /id="U3028" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.462537462537463" /psig="0.842157842157842" /xcortree=659 /SigmaFactorBS="gggctttttttattcaaccgatatatgggCTTGAAGttcaca ccagactcTGTTAAAATTCGTTTCATAGctaatgattctgataatttaaggcaggcct a" /listShort="ywaE, NA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3811937..3811956 /Source="Nicolas_upshift_promotors" /id="U3028" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.462537462537463" /psig="0.842157842157842" /xcortree=659 /SigmaFactorBS="gggctttttttattcaaccgatatatgggCTTGAAGttcaca ccagactcTGTTAAAATTCGTTTCATAGctaatgattctgataatttaaggcaggcct a" /listShort="ywaE, NA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3811947 /Source="Nicolas_upshifts" /id="U3028" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.462537462537463" /psig="0.842157842157842" /xcortree=659 /SigmaFactorBS="gggctttttttattcaaccgatatatgggCTTGAAGttcaca ccagactcTGTTAAAATTCGTTTCATAGctaatgattctgataatttaaggcaggcct a" /listShort="ywaE, NA" /GFF_Attribute="listLong" CDS 3811992..3812507 /gene="tyrZR" /locus_tag="BSU_38450" /old_locus_tag="BSU38450" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:25733610" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 25733610; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator controlling expressionof tyrZ" /protein_id="NP_391724.1" /db_xref="EnsemblGenomes-Gn:BSU38450" /db_xref="EnsemblGenomes-Tr:CAB15871" /db_xref="GOA:P25150" /db_xref="InterPro:IPR000835" /db_xref="InterPro:IPR023187" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG10556" /db_xref="UniProtKB/Swiss-Prot:P25150" /translation="MERSHQHQQLRKEEHDTLSKLKQMPVESLNLEAISIATNLYRSA QRLRVKMETEVLSTYNLSWTAFSILYDLWVWGALETRKIAELSGISTATASNVIKTLE KKSFCRKSIDTRDRRLVFVSITDSGKQAIEELYPEFHKGETELIAGMTKDEQKILTGL LRKVADNLHTT*" gene 3811992..3812507 /gene="tyrZR" /locus_tag="BSU_38450" /old_locus_tag="BSU38450" misc_RNA 3812508..3812714 /gene="tboYB" /locus_tag="BSU_misc_RNA_59" /product="T-box riboswitch specific of tyrosine tRNA ligase" /experiment="publication(s) with functional evidences, PMID:8045882, 9098041, 10943892, 11842119, 12165569, 12547201, 1317842" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8045882, 9098041, 10943892, 11842119, 12165569, 12547201, 1317842; Product type n: RNA" /function="16.3: Control" gene 3812508..3812714 /gene="tboYB" /locus_tag="BSU_misc_RNA_59" downshifts 3812674 /Source="Nicolas_upshifts" /id="D1993" /incds=0 /nref=15 /ntot=112 /MaxReadThrough="1.84575" /MaxDrop="4.56656" /score="23.8000948" /energy="-14.5" /TU="NA" /idTUdmin="U3028" /TUdmin=0 /isTUend="TRUE" CDS 3812756..3813997 /gene="tyrZ" /locus_tag="BSU_38460" /old_locus_tag="BSU38460" /EC_number="6.1.1.1" /function="16.3: Control" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:1735721, 1806041, 25733610" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1735721, 1806041, 25733610; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="tyrosyl-tRNA synthetase" /protein_id="NP_391725.1" /db_xref="EnsemblGenomes-Gn:BSU38460" /db_xref="EnsemblGenomes-Tr:CAB15872" /db_xref="GOA:P25151" /db_xref="InterPro:IPR001412" /db_xref="InterPro:IPR002305" /db_xref="InterPro:IPR002307" /db_xref="InterPro:IPR002942" /db_xref="InterPro:IPR014729" /db_xref="InterPro:IPR024088" /db_xref="InterPro:IPR024108" /db_xref="InterPro:IPR036986" /db_xref="SubtiList:BG10555" /db_xref="UniProtKB/Swiss-Prot:P25151" /translation="MMRTFEQLTASQQKEVERQLQLYMTGAHEVIPPEELKAKLVKSI STGTPLKIKLGLDPSAPDVHLGHTVVLNKLRQFQENGHIVQLLIGDFTGKIGDPTGKS AARKQLTDEEVQHNAKTYFEQFGKVLDPEKVELHYNSKWLKTLNLEDVIELAGKITVA RLMERDDFEERIAMQKPISLHEFFYPLMQGYDSVVLESDIELGGTDQHFNVLMGRHFQ ERYNKEKQVVILMPLLEGLDGVEKMSKSKHNYIGINEHPNDMYGKTMSLPDSLMKKYI HLATDLELEEKKQLVKDLETGAVHPRDAKMLLARTIVRMYHGEKAAEAAEHSFKTVFQ ENSLPEDIPAVNWKGEKTIAMIDLLVKLKLLSSKSEARRMIQNGGVRIDGEKVTDVHA KAEIRENMIIQVGKRKFLKLQ*" gene 3812756..3813997 /gene="tyrZ" /locus_tag="BSU_38460" /old_locus_tag="BSU38460" promotor_-35 3814088..3814096 /Source="Nicolas_upshift_promotors" /id="U3029" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp=1 /psig=1 /xcortree=502 /SigmaFactorBS="cactgtcttttcaaaaacgctctccatcttGCAGGAAACtcc tttagcaTCCCGAAATATTCCCCAACcatacatttaggggaggtttatttttgatgaa a" /listShort="ywaD" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3814107..3814125 /Source="Nicolas_upshift_promotors" /id="U3029" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp=1 /psig=1 /xcortree=502 /SigmaFactorBS="cactgtcttttcaaaaacgctctccatcttGCAGGAAACtcc tttagcaTCCCGAAATATTCCCCAACcatacatttaggggaggtttatttttgatgaa a" /listShort="ywaD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3814118 /Source="Nicolas_upshifts" /id="U3029" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp=1 /psig=1 /xcortree=502 /SigmaFactorBS="cactgtcttttcaaaaacgctctccatcttGCAGGAAACtcc tttagcaTCCCGAAATATTCCCCAACcatacatttaggggaggtttatttttgatgaa a" /listShort="ywaD" /GFF_Attribute="listLong" CDS 3814153..3815520 /gene="eapD" /locus_tag="BSU_38470" /old_locus_tag="BSU38470" /EC_number="3.4.11.-" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:15668014, 23426795, 26898926, 28257579" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15668014, 23426795, 26898926, 28257579; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="exported double-zinc aminopeptidase" /protein_id="NP_391726.1" /db_xref="EnsemblGenomes-Gn:BSU38470" /db_xref="EnsemblGenomes-Tr:CAB15873" /db_xref="GOA:P25152" /db_xref="InterPro:IPR003137" /db_xref="InterPro:IPR007484" /db_xref="SubtiList:BG10554" /db_xref="UniProtKB/Swiss-Prot:P25152" /translation="MKKLLTVMTMAVLTAGTLLLPAQSVTPAAHAVQISNSERELPFK AKHAYSTISQLSEAIGPRIAGTAAEKKSALLIASSMRKLKLDVKVQRFNIPDRLEGTL SSAGRDILLQAASGSAPTEEQGLTAPLYNAGLGYQKDFTADAKGKIALISRGDLTYYE KAKNAEAAGAKAVIIYNNKESLVPMTPNLSGNKVGIPVVGIKKEDGEALTQQKEATLK LKAFTNQTSQNIIGIKKPKNIKHPDIVYVTAHYDSVPFSPGANDNGSGTSVMLEMARV LKSVPSDKEIRFIAFGAEELGLLGSSHYVDHLSEKELKRSEVNFNLDMVGTSWEKASE LYVNTLDGQSNYVWESSRTAAEKIGFDSLSLTQGGSSDHVPFHEAGIDSANFIWGDPE TEEVEPWYHTPEDSIEHISKERLQQAGDLVTAAVYEAVKKEKKPKTIKKQMKAKASDI FEDIK*" gene 3814153..3815520 /gene="eapD" /locus_tag="BSU_38470" /old_locus_tag="BSU38470" downshifts 3815497 /Source="Nicolas_upshifts" /id="D1994" /incds=0 /nref=3 /ntot=37 /MaxReadThrough="1.38814" /MaxDrop="6.05871" /score="27.7635079" /energy="-13.3" /TU="NA" /idTUdmin="U3029" /TUdmin=7 /isTUend="TRUE" CDS complement(3815550..3816182) /gene="relQ" /locus_tag="BSU_38480" /old_locus_tag="BSU38480" /EC_number="2.7.6.5" /function="16.7: Manage energy" /function="16.3: Control" /function="16.14: Store" /experiment="publication(s) with functional evidences, PMID:17714452, 18067544, 19447912, 22333191, 22950019, 24163341, 25331430, 26211718" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 17714452, 18067544, 19447912, 22333191, 22950019, 24163341, 25331430, 26211718; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="(p)ppGpp synthetase" /protein_id="NP_391727.1" /db_xref="EnsemblGenomes-Gn:BSU38480" /db_xref="EnsemblGenomes-Tr:CAB15874" /db_xref="GOA:P39583" /db_xref="InterPro:IPR007685" /db_xref="SubtiList:BG10553" /db_xref="UniProtKB/Swiss-Prot:P39583" /translation="MDLSVTHMDDLKTVMEDWKNELLVYKFALDALDTKFSIISQEYN LIHGHNPIEHTKSRVKSFESIVNKLMRKGCEITTKEMKEHIHDIAGVRIICSFISDIY NVVNVLKQHEDLRIVKVKDYIQTPKPNGYRSLHLIIEMPVNLTNRVEYVKAEIQIRTI AMDFWASLEHKIYYKLNNDVPKQLTDELKEAAEIAHYLDEKMLGIKKEVD*" gene complement(3815550..3816182) /gene="relQ" /locus_tag="BSU_38480" /old_locus_tag="BSU38480" downshifts complement(3815568) /Source="Nicolas_upshifts" /id="D1995" /incds=0 /nref=200 /ntot=257 /MaxReadThrough="2.49976" /MaxDrop="5.49802" /score="47.236042" /energy="-13.3" /TU="NA" /idTUdmin="U3030" /TUdmin="-2" /isTUend="TRUE" promotor_-10 complement(3816218..3816233) /Source="Nicolas_upshift_promotors" /id="U3030" /multdbtbs="SigW" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1644 /SigmaFactorBS="tacaatcgaccgcattttgtaaaaaaattcatAGAACCTTGc agcagacagggACGTCTAGTACATGGAcagcggataaagttccgttaaaggagatgac g" /listShort="ywaC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3816226) /Source="Nicolas_upshifts" /id="U3030" /multdbtbs="SigW" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1644 /SigmaFactorBS="tacaatcgaccgcattttgtaaaaaaattcatAGAACCTTGc agcagacagggACGTCTAGTACATGGAcagcggataaagttccgttaaaggagatgac g" /listShort="ywaC" /GFF_Attribute="listLong" promotor_-35 complement(3816246..3816254) /Source="Nicolas_upshift_promotors" /id="U3030" /multdbtbs="SigW" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1644 /SigmaFactorBS="tacaatcgaccgcattttgtaaaaaaattcatAGAACCTTGc agcagacagggACGTCTAGTACATGGAcagcggataaagttccgttaaaggagatgac g" /listShort="ywaC" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3816324..3817259) /gene="menA" /locus_tag="BSU_38490" /old_locus_tag="BSU38490" /EC_number="2.5.1.74" /function="16.2: Construct biomass (Anabolism)" /function="16.10: Respire" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 6780514, 9573170, 12682299, 15849754, 16850406; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="1,4-dihydroxy-2-naphthoate octaprenyltransferase" /protein_id="NP_391728.1" /db_xref="EnsemblGenomes-Gn:BSU38490" /db_xref="EnsemblGenomes-Tr:CAB15875" /db_xref="GOA:P39582" /db_xref="InterPro:IPR000537" /db_xref="InterPro:IPR004657" /db_xref="InterPro:IPR026046" /db_xref="SubtiList:BG10552" /db_xref="UniProtKB/Swiss-Prot:P39582" /translation="MNQTNKGEGQTAPQKESMGQILWQLTRPHTLTASFVPVLLGTVL AMFYVKVDLLLFLAMLFSCLWIQIATNLFNEYYDFKRGLDTAESVGIGGAIVRHGMKP KTILQLALASYGIAILLGVYICASSSWWLALIGLVGMAIGYLYTGGPLPIAYTPFGEL FSGICMGSVFVLISFFIQTDKINMQSILISIPIAILVGAINLSNNIRDIEEDKKGGRK TLAILMGHKGAVTLLAASFAVAYIWVVGLVITGAASPWLFVVFLSVPKPVQAVKGFVQ NEMPMNMIVAMKSTAQTNTFFGFLLSIGLLISYFR*" gene complement(3816324..3817259) /gene="menA" /locus_tag="BSU_38490" /old_locus_tag="BSU38490" downshifts complement(3816336) /Source="Nicolas_upshifts" /id="D1996" /incds=0 /nref=10 /ntot=113 /MaxReadThrough="3.08081" /MaxDrop="4.6874" /score="16.8971767" /energy="-8.5" /TU="NA" /idTUdmin="U3032" /TUdmin=0 /isTUend="TRUE" promotor_-35 3817003..3817012 /Source="Nicolas_upshift_promotors" /id="U3031" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.97902097902098" /psig="0.97902097902098" /xcortree=1379 /SigmaFactorBS="cgtacaatggcccctccgattccgactgattctGCTGTATCT AatccgcgtttaaaATCATAGTATTCATTAAATAagttcgtcgcgatctggatccata g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3817026..3817045 /Source="Nicolas_upshift_promotors" /id="U3031" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.97902097902098" /psig="0.97902097902098" /xcortree=1379 /SigmaFactorBS="cgtacaatggcccctccgattccgactgattctGCTGTATCT AatccgcgtttaaaATCATAGTATTCATTAAATAagttcgtcgcgatctggatccata g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3817030 /Source="Nicolas_upshifts" /id="U3031" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.97902097902098" /psig="0.97902097902098" /xcortree=1379 /SigmaFactorBS="cgtacaatggcccctccgattccgactgattctGCTGTATCT AatccgcgtttaaaATCATAGTATTCATTAAATAagttcgtcgcgatctggatccata g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" S_feature complement(3817260..3817347) /Source="Nicolas_S_feature" /locus_tag="new_3951662_3951749_c" /HighExp="LBGstat, Paraq, G180, LBGexp, G135, Oxctl, C30, Cold, Diami, LBGtran" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.81271400000000005" /TUshortSig="SigA, Sig-" /TUshortPSig="0.999, 0.498" /TUlongSig="NA" /TUlongPSig="NA" /label="S1478" promotor_-10 complement(3817330..3817349) /Source="Nicolas_upshift_promotors" /id="U3032" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.801198801198801" /psig="0.999000999001" /xcortree=2514 /SigmaFactorBS="gaagcgtataataagaaagaaaacgccttcttgcggtaTCTT GtgaaataagggagaaGTCATTATGATAGATAAGGAagcaaaaggagttttttattaa g" /listShort="S1478, menA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3817347) /Source="Nicolas_upshifts" /id="U3032" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.801198801198801" /psig="0.999000999001" /xcortree=2514 /SigmaFactorBS="gaagcgtataataagaaagaaaacgccttcttgcggtaTCTT GtgaaataagggagaaGTCATTATGATAGATAAGGAagcaaaaggagttttttattaa g" /listShort="S1478, menA" /GFF_Attribute="listLong" promotor_-35 complement(3817365..3817369) /Source="Nicolas_upshift_promotors" /id="U3032" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.801198801198801" /psig="0.999000999001" /xcortree=2514 /SigmaFactorBS="gaagcgtataataagaaagaaaacgccttcttgcggtaTCTT GtgaaataagggagaaGTCATTATGATAGATAAGGAagcaaaaggagttttttattaa g" /listShort="S1478, menA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(3817392..3817404) /Source="Nicolas_upshift_promotors" /id="U3033" /multdbtbs="-" /comp="M8" /sig="Sig-" /pcomp="0.497502497502497" /psig="0.497502497502497" /xcortree=2049 /SigmaFactorBS="cctgttcgttcaagtgaaagcagaaacCTAATGAaatcaggg cgagaaGCGTATAATAAGAaagaaaacgccttcttgcggtatcttgtgaaataaggga g" /listShort="S1478, menA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3817392) /Source="Nicolas_upshifts" /id="U3033" /multdbtbs="-" /comp="M8" /sig="Sig-" /pcomp="0.497502497502497" /psig="0.497502497502497" /xcortree=2049 /SigmaFactorBS="cctgttcgttcaagtgaaagcagaaacCTAATGAaatcaggg cgagaaGCGTATAATAAGAaagaaaacgccttcttgcggtatcttgtgaaataaggga g" /listShort="S1478, menA" /GFF_Attribute="listLong" promotor_-35 complement(3817419..3817425) /Source="Nicolas_upshift_promotors" /id="U3033" /multdbtbs="-" /comp="M8" /sig="Sig-" /pcomp="0.497502497502497" /psig="0.497502497502497" /xcortree=2049 /SigmaFactorBS="cctgttcgttcaagtgaaagcagaaacCTAATGAaatcaggg cgagaaGCGTATAATAAGAaagaaaacgccttcttgcggtatcttgtgaaataaggga g" /listShort="S1478, menA" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3817422..3817556) /locus_tag="BSU_38495" /old_locus_tag="BSU38495" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_009514012.1" /translation="MECFELIHNKGKDTWSQKIFLTFKKCNVLKKIFLYLFVQVKAET *" gene complement(3817422..3817556) /locus_tag="BSU_38495" /old_locus_tag="BSU38495" promotor_-35 3817503..3817510 /Source="Nicolas_upshift_promotors" /id="U3034" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.884115884115884" /psig="0.998001998001998" /xcortree=2465 /SigmaFactorBS="tacattacactttttaaaagttaaaaagatCTTTTGACtcca ggtatctttTCCTTTATTATGAATCAGCTcgaaacattccattcttgcccttgcaggt a" /listShort="S1479" /listLong="ywzH, dltA, dltB, dltC, dltD, S1480, dltE, ilvK" /label="promotor_-35" promotor_-10 3817524..3817543 /Source="Nicolas_upshift_promotors" /id="U3034" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.884115884115884" /psig="0.998001998001998" /xcortree=2465 /SigmaFactorBS="tacattacactttttaaaagttaaaaagatCTTTTGACtcca ggtatctttTCCTTTATTATGAATCAGCTcgaaacattccattcttgcccttgcaggt a" /listShort="S1479" /listLong="ywzH, dltA, dltB, dltC, dltD, S1480, dltE, ilvK" /label="promotor_-10" upshifts 3817533 /Source="Nicolas_upshifts" /id="U3034" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.884115884115884" /psig="0.998001998001998" /xcortree=2465 /SigmaFactorBS="tacattacactttttaaaagttaaaaagatCTTTTGACtcca ggtatctttTCCTTTATTATGAATCAGCTcgaaacattccattcttgcccttgcaggt a" /listShort="S1479" /listLong="ywzH, dltA, dltB, dltC, dltD, S1480, dltE, ilvK" S_feature 3817536..3817640 /Source="Nicolas_S_feature" /locus_tag="new_3951938_3952042" /HighExp="H2O2, Paraq, Oxctl, G180, G150, C30, G135, LBGstat, dia15, Diami" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.998" /TUlongSig="NA" /TUlongPSig="NA" /label="S1479" promotor_-35 3817635..3817644 /Source="Nicolas_upshift_promotors" /id="U3035" /multdbtbs="SigX" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=2508 /SigmaFactorBS="cattttcaaaaacatacgccgatatattaatttgagggagat tagggaaaaaaTGAAACTTTTtgagcatctgaTCGTCAAATAATCATGtgattgtcga a" /listShort="ywzH, dltA, dltB, dltC, dltD, S1480, dltE, ilvK" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 3817642 /Source="Nicolas_upshifts" /id="U3035" /multdbtbs="SigX" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=2508 /SigmaFactorBS="cattttcaaaaacatacgccgatatattaatttgagggagat tagggaaaaaaTGAAACTTTTtgagcatctgaTCGTCAAATAATCATGtgattgtcga a" /listShort="ywzH, dltA, dltB, dltC, dltD, S1480, dltE, ilvK" /GFF_Attribute="listLong" promotor_-10 3817656..3817671 /Source="Nicolas_upshift_promotors" /id="U3035" /multdbtbs="SigX" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=2508 /SigmaFactorBS="cattttcaaaaacatacgccgatatattaatttgagggagat tagggaaaaaaTGAAACTTTTtgagcatctgaTCGTCAAATAATCATGtgattgtcga a" /listShort="ywzH, dltA, dltB, dltC, dltD, S1480, dltE, ilvK" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3817678) /Source="Nicolas_upshifts" /id="U3036" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.976023976023976" /psig="0.001998001998002" /xcortree=298 /SigmaFactorBS="tttttcatacagctgtttcattaattgcagcatatcaaaaat tcCCTTCCCGTTTTTTCgacaatcacatgattatttgacgatcagatgctcaaaaagt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" misc_feature complement(3817680..3817694) /Source="Nicolas_upshift_promotors" /id="U3036" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.976023976023976" /psig="0.001998001998002" /xcortree=298 /SigmaFactorBS="tttttcatacagctgtttcattaattgcagcatatcaaaaat tcCCTTCCCGTTTTTTCgacaatcacatgattatttgacgatcagatgctcaaaaagt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" CDS 3817706..3817855 /gene="ywzH" /locus_tag="BSU_38499" /old_locus_tag="BSU38499" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical membrane protein" /protein_id="YP_003097795.1" /db_xref="EnsemblGenomes-Gn:BSU38499" /db_xref="EnsemblGenomes-Tr:CAX52708" /db_xref="GOA:C0H3T3" /db_xref="InterPro:IPR021008" /db_xref="UniProtKB/Swiss-Prot:C0H3T3" /translation="MLQLMKQLYEKPAVKWTCHTGFYLMILLVLFFMYGFHTANTGSY IYNDF*" gene 3817706..3817855 /gene="ywzH" /locus_tag="BSU_38499" /old_locus_tag="BSU38499" CDS 3817873..3819384 /gene="dltA" /locus_tag="BSU_38500" /old_locus_tag="BSU38500" /EC_number="6.1.1.13" /function="16.8: Protect" /function="16.13: Shape" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:7797557, 11222605, 14665680, 15955059, 18847223, 19324056, 23858088" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7797557, 11222605, 14665680, 15955059, 18847223, 19324056, 23858088; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="D-alanine:D-alanyl-carrier protein ligase subunit" /protein_id="NP_391729.1" /db_xref="EnsemblGenomes-Gn:BSU38500" /db_xref="EnsemblGenomes-Tr:CAB15876" /db_xref="GOA:P39581" /db_xref="InterPro:IPR000873" /db_xref="InterPro:IPR010071" /db_xref="InterPro:IPR010072" /db_xref="InterPro:IPR020845" /db_xref="InterPro:IPR025110" /db_xref="PDB:3E7W" /db_xref="PDB:3E7X" /db_xref="SubtiList:BG10551" /db_xref="UniProtKB/Swiss-Prot:P39581" /translation="MKLLHAIQTHAETYPQTDAFRSQGQSLTYQELWEQSDRAAAAIQ KRISGEKKSPILVYGHMEPHMIVSFLGSVKAGHPYIPVDLSIPSERIAKIIESSGAEL LIHAAGLSIDAVGQQIQTVSAEELLENEGGSVSQDQWVKEHETFYIIYTSGSTGNPKG VQISAANLQSFTDWICADFPVSGGKIFLNQAPFSFDLSVMDLYPCLQSGGTLHCVTKD AVNKPKVLFEELKKSGLNVWTSTPSFVQMCLMDPGFSQDLLPHADTFMFCGEVLPVSV AKALLERFPKAKIFNTYGPTEATVAVTSVEITNDVISRSESLPVGFAKPDMNIFIMDE EGQPLPEGEKGEIVIAGPSVSRGYLGEPELTEKAFFSHEGQWAYRTGDAGFIQDGQIF CQGRLDFQIKLHGYRMELEEIEFHVRQSQYVRSAVVIPYQPNGTVEYLIAAIVPEEHE FEKEFQLTSAIKKELAASLPAYMIPRKFIYQDHIQMTANGKIDRKRIGEEVLV*" gene 3817873..3819384 /gene="dltA" /locus_tag="BSU_38500" /old_locus_tag="BSU38500" CDS 3819381..3820568 /gene="dltB" /locus_tag="BSU_38510" /old_locus_tag="BSU38510" /function="16.1: Circulate" /function="16.13: Shape" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 11222605, 12028417, 14665680, 15849754, 16850406, 17263852; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="putative D-alanine transferase from DCP to undecaprenylphosphate for lipoteichoic acid and wall teichoic acid" /protein_id="NP_391730.1" /db_xref="EnsemblGenomes-Gn:BSU38510" /db_xref="EnsemblGenomes-Tr:CAB15877" /db_xref="GOA:P39580" /db_xref="InterPro:IPR004299" /db_xref="InterPro:IPR024024" /db_xref="InterPro:IPR024194" /db_xref="SubtiList:BG10550" /db_xref="UniProtKB/Swiss-Prot:P39580" /translation="MTPYSSFLFFILLGILLLPTIILGLNGKRFQAYNMFISIIILAL IFSHDLHGVIALCLFTIWQVLLISGYLAYRQKANSGFVFCGAVIASILPLFLSKIWPF LSHPQPHHPPHNLISFLGISYLTFKGVQLIMEARDGLLKEQLPLHRLLYFILFFPTIS SGPIDRYRRFVKDEQKAWTKEEYADLLYTGIHKIFIGFLYKFIIGYAINTYFIMNLPA ITHNKILGNLLYMYGYSMYLFFDFAGYTMFAVGVSYIMGIKSPENFNKPFISKNIKDF WNRWHMSLSFWFRDYVFMRFVFWMTKKKWIKNRMAVSNIGYFLLFMLMGVWHGLAPQY IIYGLYHAVLMTCYNFFEKWNKKYKWLPSNRWTTILAIVITFHFVCFGFYIFSGKPFH HHH*" gene 3819381..3820568 /gene="dltB" /locus_tag="BSU_38510" /old_locus_tag="BSU38510" CDS 3820585..3820821 /gene="dltC" /locus_tag="BSU_38520" /old_locus_tag="BSU38520" /function="16.13: Shape" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:7797557, 11222605, 14665680, 15955059, 26193422" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7797557, 11222605, 14665680, 15955059, 26193422; Product type c: carrier" /codon_start=1 /transl_table=11 /product="D-alanyl carrier protein" /protein_id="NP_391731.1" /db_xref="EnsemblGenomes-Gn:BSU38520" /db_xref="EnsemblGenomes-Tr:CAB15878" /db_xref="GOA:P39579" /db_xref="InterPro:IPR003230" /db_xref="InterPro:IPR009081" /db_xref="InterPro:IPR036736" /db_xref="PDB:4BPF" /db_xref="PDB:4BPG" /db_xref="PDB:4BPH" /db_xref="SubtiList:BG10549" /db_xref="UniProtKB/Swiss-Prot:P39579" /translation="MDFKQEVLDVLAEVCQDDIVKENPDIEIFEEGLLDSFGTVELLL AIENRFDILVPITEFDRDVWNTPNNIVNQLSELK*" gene 3820585..3820821 /gene="dltC" /locus_tag="BSU_38520" /old_locus_tag="BSU38520" CDS 3820821..3821999 /gene="dltD" /locus_tag="BSU_38530" /old_locus_tag="BSU38530" /function="16.2: Construct biomass (Anabolism)" /function="16.13: Shape" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 11222605, 12028417, 14665680, 17263852, 17600057, 23858088; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="putative D-alanine from undecaprenylphosphate tothe polyglycerolphosphate chain for lipoteichoic acid andwall teichoic acid synthesis" /protein_id="NP_391732.1" /db_xref="EnsemblGenomes-Gn:BSU38530" /db_xref="EnsemblGenomes-Tr:CAB15879" /db_xref="GOA:P39578" /db_xref="InterPro:IPR006998" /db_xref="InterPro:IPR023896" /db_xref="InterPro:IPR036514" /db_xref="SubtiList:BG10548" /db_xref="UniProtKB/Swiss-Prot:P39578" /translation="MKKRFFGPIILAFILFAGAIAIPSSWLTGFITDKRVKESATALN PSMFQGLYLQDQMLKDPTYLPIYGSSELSRLDEFHPSNYFQVNNEGFTPYLVGKGGSQ SLIHSLNFAAHMDQLKGKKIVFIVSPQWFIKRGSDEQHFAPNYSALQGLDLAFNDQID PEIKKKMMKRMLRFKAVQNDAILSELYKAMVNGQTWKVNALKPAAKVYYSMLEKKDLY YSTTESSGPKRYISQSVKDKSWSELNKLADQSGKRHSGSNDFHIDNPVYKKLKPKVPK LKGKNKGRSYAVSPEYGDFEMMLDILKDAGAEPMFVTIPVNGKWYDYTGFPKKGRTDY YKKVNKQIRAKGFQVADFSGHEYDPYFMKDTIHIGWKGWVYVDKAIDEFYKTGKVTSS *" gene 3820821..3821999 /gene="dltD" /locus_tag="BSU_38530" /old_locus_tag="BSU38530" S_feature 3822000..3822089 /Source="Nicolas_S_feature" /locus_tag="new_3956402_3956491" /HighExp="Paraq, H2O2, Oxctl, LBGexp, Lbexp, dia0, C30, Cold, G150, LPh" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigWXY" /TUshortPSig=1 /TUlongSig="SigA" /TUlongPSig="0.998" /label="S1480" CDS 3822090..3822848 /gene="dltE" /locus_tag="BSU_38540" /old_locus_tag="BSU38540" /EC_number="1.-.-.-" /function="16.8: Protect" /function="16.13: Shape" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 7797557, 14665680; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative oxidoreductase" /protein_id="NP_391733.2" /db_xref="EnsemblGenomes-Gn:BSU38540" /db_xref="EnsemblGenomes-Tr:CAB15880" /db_xref="GOA:P39577" /db_xref="InterPro:IPR002347" /db_xref="InterPro:IPR020904" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG10547" /db_xref="UniProtKB/Swiss-Prot:P39577" /translation="MKMTNNTVLITGGSAGIGLELAKRLLELGNEVIICGRSEARLAE AKQQLPNIHTKQCDVADRSQREALYEWALKEYPNLNVLVNNAGIQKEIDFKKGTEELF VDGDEIELNFQAPVHLSALFTPHLMKQPEAAIVQVTSGLAFNPLAVYPVYCATKAALH SFSLTLRHQLRDTSVEVIEMAPPMVDTGLNQKSRDKQGLTYRGISSEEYVQYFLDGLK EGKQEITNERVEGLRDATRADYDRLFEQMNTQEN*" gene 3822090..3822848 /gene="dltE" /locus_tag="BSU_38540" /old_locus_tag="BSU38540" downshifts 3822816 /Source="Nicolas_upshifts" /id="D1997" /incds=0 /nref=48 /ntot=172 /MaxReadThrough="5.94016" /MaxDrop="4.72547" /score="22.6844301" /energy="-13.7" /TU="U3035" /idTUdmin="U3035" /TUdmin="-1254" /isTUend="FALSE" S_feature complement(3822850..3824077) /Source="Nicolas_S_feature" /locus_tag="new_3957252_3958479_c" /HighExp="T0.30H, T1.0H, T1.30H, C30, B60, T2.0H, C90, Gly, T2.30H, S8" /AntisenseName="ilvK" /AntisenseCor="-0.12928749136401099" /AntisenseRegPval="-1.5" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.978" /TUlongSig="NA" /TUlongPSig="NA" /label="S1481" promotor_-35 3822896..3822903 /Source="Nicolas_upshift_promotors" /id="U3037" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.82017982017982" /psig="0.999000999001" /xcortree=3073 /SigmaFactorBS="gaatttcttacaaatttgagcaaaccTATTGCGAttatttgt tgaagGTATACAATAGAATATAATTattttcaaataagtttgataatataaacaattt a" /listShort="ilvK" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3822917..3822936 /Source="Nicolas_upshift_promotors" /id="U3037" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.82017982017982" /psig="0.999000999001" /xcortree=3073 /SigmaFactorBS="gaatttcttacaaatttgagcaaaccTATTGCGAttatttgt tgaagGTATACAATAGAATATAATTattttcaaataagtttgataatataaacaattt a" /listShort="ilvK" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3822930 /Source="Nicolas_upshifts" /id="U3037" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.82017982017982" /psig="0.999000999001" /xcortree=3073 /SigmaFactorBS="gaatttcttacaaatttgagcaaaccTATTGCGAttatttgt tgaagGTATACAATAGAATATAATTattttcaaataagtttgataatataaacaattt a" /listShort="ilvK" /GFF_Attribute="listLong" CDS 3822989..3824080 /gene="ilvK" /locus_tag="BSU_38550" /old_locus_tag="BSU38550" /EC_number="2.6.1.42" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:12670965, 17611193, 22938038" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12670965, 17611193, 22938038; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="branched-chain amino acid aminotransferase" /protein_id="NP_391734.2" /db_xref="EnsemblGenomes-Gn:BSU38550" /db_xref="EnsemblGenomes-Tr:CAB15881" /db_xref="GOA:P39576" /db_xref="InterPro:IPR001544" /db_xref="InterPro:IPR005786" /db_xref="InterPro:IPR018300" /db_xref="InterPro:IPR033939" /db_xref="InterPro:IPR036038" /db_xref="SubtiList:BG10546" /db_xref="UniProtKB/Swiss-Prot:P39576" /translation="MTKQTIRVELTSTKKPKPDPNQLSFGRVFTDHMFVMDYAADKGW YDPRIIPYQPLSMDPAAMVYHYGQTVFEGLKAYVSEDDHVLLFRPEKNMERLNQSNDR LCIPQIDEEQVLEGLKQLVAIDKDWIPNAEGTSLYIRPFIIATEPFLGVAASHTYKLL IILSPVGSYYKEGIKPVKIAVESEFVRAVKGGTGNAKTAGNYASSLKAQQVAEEKGFS QVLWLDGIEKKYIEEVGSMNIFFKINGEIVTPMLNGSILEGITRNSVIALLKHWGLQV SERKIAIDEVIQAHKDGILEEAFGTGTAAVISPVGELIWQDETLSINNGETGEIAKKL YDTITGIQKGAVADEFGWTTEVAALTESK*" gene 3822989..3824080 /gene="ilvK" /locus_tag="BSU_38550" /old_locus_tag="BSU38550" downshifts 3823982 /Source="Nicolas_upshifts" /id="D1998" /incds=1 /nref=10 /ntot=90 /MaxReadThrough="6.0829" /MaxDrop="3.1965" /score="32.8755878" /energy="-13.6" /TU="U3035,U3037" /idTUdmin="U3035" /TUdmin="-88" /isTUend="FALSE" downshifts 3824070 /Source="Nicolas_upshifts" /id="D1999" /incds=0 /nref=157 /ntot=264 /MaxReadThrough="2.21106" /MaxDrop="6.83094" /score="32.8755878" /energy="-13.6" /TU="NA" /idTUdmin="U3035" /TUdmin=0 /isTUend="TRUE" CDS complement(3824114..3825442) /gene="licH" /locus_tag="BSU_38560" /old_locus_tag="BSU38560" /EC_number="3.2.1.86" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2b: Function from indirect experimental evidences (e.g. phenotypes); PubMedId: 8990303, 10438772, 22720735, 23874669, 24673833; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="6-phospho-beta-glucosidase" /protein_id="NP_391735.1" /db_xref="EnsemblGenomes-Gn:BSU38560" /db_xref="EnsemblGenomes-Tr:CAB15882" /db_xref="GOA:P46320" /db_xref="InterPro:IPR001088" /db_xref="InterPro:IPR015955" /db_xref="InterPro:IPR019802" /db_xref="InterPro:IPR022616" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG11350" /db_xref="UniProtKB/Swiss-Prot:P46320" /translation="MTKGLKIVTIGGGSSYTPELVEGFIKRYDELPVRELWLVDIPEG EEKLNIVGTLAKRMVEKAGVPIDIHLTLDRRKALKDADFVTTQFRVGLLQARAKDERI PLKYGVIGQETNGPGGLFKGLRTIPVILEIAKDIEELCPNAWLVNFTNPAGMVTEALL RYSNLKKVVGLCNVPIGIKMGVAKALDVDVDRVEVQFAGLNHMVFGLDVFLDGVSVKE QVIEAMGDPKNAMTMKNISGAEWEPDFLKALNVIPCGYHRYYFKTKEMLEHELEASQT EGTRAEVVQKVEKELFELYKDPNLAIKPPQLEKRGGAYYSDAACNLISSIYNDKHDIQ PVNTINNGAIASIPDDSAVEVNCVMTKTGPKPIAVGDLPVSVRGLVQQIKSFERVAAE AAVTGDYQTALLAMTINPLVPSDTVAKQILDEMLEAHKAYLPQFFNKIEA*" gene complement(3824114..3825442) /gene="licH" /locus_tag="BSU_38560" /old_locus_tag="BSU38560" downshifts complement(3824122) /Source="Nicolas_upshifts" /id="D2000" /incds=0 /nref=12 /ntot=98 /MaxReadThrough="4.92442" /MaxDrop="6.75565" /score="45.1562234" /energy="-15.7" /TU="U3038" /idTUdmin="U3038" /TUdmin="-152" /isTUend="FALSE" CDS complement(3825439..3825771) /gene="licA" /locus_tag="BSU_38570" /old_locus_tag="BSU38570" /function="16.1: Circulate" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:8990303, 10438772, 22720735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8990303, 10438772, 22720735; Product type t: transporter" /codon_start=1 /transl_table=11 /product="phosphotransferase system (PTS) lichenan-specific enzyme IIA component" /protein_id="NP_391736.1" /db_xref="EnsemblGenomes-Gn:BSU38570" /db_xref="EnsemblGenomes-Tr:CAB15883" /db_xref="GOA:P46319" /db_xref="InterPro:IPR003188" /db_xref="InterPro:IPR036542" /db_xref="SubtiList:BG11349" /db_xref="UniProtKB/Swiss-Prot:P46319" /translation="MNEEMEQIIFQIILHGGNGRSSAMEAIAAAKSGDAEEARKKLQD AAEELSKAHHYQTELIQNEAGGEKTEMTLLMVHAQDHLMNAMTVKDMAAEIIELYEKI TEQRGASI*" gene complement(3825439..3825771) /gene="licA" /locus_tag="BSU_38570" /old_locus_tag="BSU38570" CDS complement(3825790..3827148) /gene="licC" /locus_tag="BSU_38580" /old_locus_tag="BSU38580" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:8990303, 10438772, 15849754, 16850406" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8990303, 10438772, 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="phosphotransferase system (PTS) lichenan-specific enzyme IIC component" /protein_id="NP_391737.1" /db_xref="EnsemblGenomes-Gn:BSU38580" /db_xref="EnsemblGenomes-Tr:CAB15884" /db_xref="GOA:P46317" /db_xref="InterPro:IPR003352" /db_xref="InterPro:IPR004501" /db_xref="InterPro:IPR004796" /db_xref="SubtiList:BG11348" /db_xref="UniProtKB/Swiss-Prot:P46317" /translation="MNKVNQILEEKVMPIAGRIAGQRHLQALRDGIILTMPLIIIGSF FLIIGNLPIPGYAEFMAKTFGSSWSEKLAYPVDATFEIMGLVAAFGIAYRLAEKYGVD ALSAGAISLAAFLLATPYQVPFMPDGATKEIMVGGGIPLSLMGSKGLFVAMIIAMVST EIYRLIIQRNLVFKMPDGVPPAVSKSFVALIPGFAVIFLIWAARLIVEATPFESLHNI VSVLLGTPLSILGGSLGGSLVAEAVKMLLWACGLHGANIVGGVMAPIWYGAMDANRIA FQAGEELPKIFTQQFFDIWVNIGGSGATLALVVTMFLRARSKQMKQLGKLAVGPAIFN INEPIIFGMPIVMNPMLLLPFIITPLVTVTLTYIGMSTGLVAKPAGIAVPWTMPPIFS GYLATGGKVSGAVMQAINIAVSFVVYYPFFRMWDKQKLKEENDLELVQTPAATDDKEA AL*" gene complement(3825790..3827148) /gene="licC" /locus_tag="BSU_38580" /old_locus_tag="BSU38580" CDS complement(3827164..3827472) /gene="licB" /locus_tag="BSU_38590" /old_locus_tag="BSU38590" /EC_number="2.7.1.-" /function="16.1: Circulate" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:8990303, 10438772, 23874669" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8990303, 10438772, 23874669; Product type t: transporter" /codon_start=1 /transl_table=11 /product="phosphotransferase system (PTS) lichenan-specific enzyme IIB component" /protein_id="NP_391738.1" /db_xref="EnsemblGenomes-Gn:BSU38590" /db_xref="EnsemblGenomes-Tr:CAB15885" /db_xref="GOA:P46318" /db_xref="InterPro:IPR003501" /db_xref="InterPro:IPR013012" /db_xref="InterPro:IPR036095" /db_xref="SubtiList:BG11347" /db_xref="UniProtKB/Swiss-Prot:P46318" /translation="MNILLVCAAGMSTSLLVSKMEKSAQEQGKDYTIWAVSGDSVQNH IDKADVLLLGPQVRYMLPQLKKLGESKGVPVDVINTVHYGTCNGAEVLKSAEQLGHVS *" gene complement(3827164..3827472) /gene="licB" /locus_tag="BSU_38590" /old_locus_tag="BSU38590" promotor_-10 complement(3827517..3827536) /Source="Nicolas_upshift_promotors" /id="U3038" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.353646353646354" /psig="0.978021978021978" /xcortree=354 /SigmaFactorBS="tatataccttttttccgttgcctgcggaaaaaccctgAGTGT TTatgaaagcgatttCATAATATGATGATAGCAACagcaggacattacaaaattgatc a" /listShort="licB, licC, licA, licH, S1481" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3827533) /Source="Nicolas_upshifts" /id="U3038" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.353646353646354" /psig="0.978021978021978" /xcortree=354 /SigmaFactorBS="tatataccttttttccgttgcctgcggaaaaaccctgAGTGT TTatgaaagcgatttCATAATATGATGATAGCAACagcaggacattacaaaattgatc a" /listShort="licB, licC, licA, licH, S1481" /GFF_Attribute="listLong" promotor_-35 complement(3827550..3827556) /Source="Nicolas_upshift_promotors" /id="U3038" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.353646353646354" /psig="0.978021978021978" /xcortree=354 /SigmaFactorBS="tatataccttttttccgttgcctgcggaaaaaccctgAGTGT TTatgaaagcgatttCATAATATGATGATAGCAACagcaggacattacaaaattgatc a" /listShort="licB, licC, licA, licH, S1481" /GFF_Attribute="listLong" /label="promotor_-35" downshifts complement(3827601) /Source="Nicolas_upshifts" /id="D2001" /incds=0 /nref=3 /ntot=74 /MaxReadThrough="3.19679" /MaxDrop="2.70222" /score="27.6067633" /energy="-11.1" /TU="U3040" /idTUdmin="U3040" /TUdmin="-45" /isTUend="FALSE" CDS complement(3827601..3829526) /gene="licR" /locus_tag="BSU_38600" /old_locus_tag="BSU38600" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:8990303, 9353933, 10438772" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8990303, 9353933, 10438772; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional activator of the lichenan operon" /protein_id="NP_391739.1" /db_xref="EnsemblGenomes-Gn:BSU38600" /db_xref="EnsemblGenomes-Tr:CAB15886" /db_xref="GOA:P46321" /db_xref="InterPro:IPR002178" /db_xref="InterPro:IPR007737" /db_xref="InterPro:IPR011608" /db_xref="InterPro:IPR013011" /db_xref="InterPro:IPR013196" /db_xref="InterPro:IPR016152" /db_xref="InterPro:IPR036095" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="InterPro:IPR036634" /db_xref="SubtiList:BG11346" /db_xref="UniProtKB/Swiss-Prot:P46321" /translation="MLHGRLRDILRLLMAAEAPVTSSFFAAQLNVTTRTVRNDIKELQ GVLSGHGAFVQSVRGSGYKLRIDDEQVFRTLLQDEFQQKKGLPVLPEERMAYLMKRLL LADHYLKLDELAEELFISKSTLQTDLKEVKKRLLPYRIVMETRPNYGFKLRGDEVQMR YCMAEYIVDERETEIDVLNEKADILPKEEIEIIRSAILKKMKNDRIPLSNMGLNNLII HIAIACKRIRTENYVSLFPKDMDHILHQKEYQAAEAIVKELESKLSVTFPKDETAYIT MHLLGTKRMTQSQCGEDTFSIEEETDQLTLAMIKAVDRELKLGILHDKELKIGLALHM KPAISRNRYGMNLRNPMLAAIKEHYPLAFEAGIIAGIVIKEQTGIEIHENEIGYLALH FGAAIERKKTESPPKRCIIVCASGAGSAQLLREKLRSHFGKRLDILGTAEYYSLDQMS YESIDFVISTIPIKKELPVPVLKVNTILGGTDFTKIESILSDEKEKANRYLKKELVFF QEDLRSKEEVIQFLGQKVVECGFADEEIIDSIFEREDMSPTCFGNLVAIPHPLVPQTK TTFWAVCTLKKPIDWESQRVQFVCLLCVEKENKADLQSMYKLLGSILDDPAAMNQLIK CRSYQELSDVFDQKMLS*" gene complement(3827601..3829526) /gene="licR" /locus_tag="BSU_38600" /old_locus_tag="BSU38600" promotor_-35 3828264..3828273 /Source="Nicolas_upshift_promotors" /id="U3039" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1369 /SigmaFactorBS="aaatgggaacgcagtttttcgcgcagaagCTGGGCGCTTccg gctcccgatgCGCATACAATGATACAGCGTttcggcgggctttctgttttttttcgtt c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3828287..3828306 /Source="Nicolas_upshift_promotors" /id="U3039" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1369 /SigmaFactorBS="aaatgggaacgcagtttttcgcgcagaagCTGGGCGCTTccg gctcccgatgCGCATACAATGATACAGCGTttcggcgggctttctgttttttttcgtt c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3828295 /Source="Nicolas_upshifts" /id="U3039" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1369 /SigmaFactorBS="aaatgggaacgcagtttttcgcgcagaagCTGGGCGCTTccg gctcccgatgCGCATACAATGATACAGCGTttcggcgggctttctgttttttttcgtt c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 complement(3829599..3829616) /Source="Nicolas_upshift_promotors" /id="U3040" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.699300699300699" /psig=1 /xcortree=3153 /SigmaFactorBS="gctgtttttttataggtcagttttccctctagtcctccggat gttCATTGACTtgccattctctccaTTATAGAATTTATATACAtttcgcatcccttca t" /listShort="licR" /listLong="licB, licC, licA, licH" /label="promotor_-10" upshifts complement(3829623) /Source="Nicolas_upshifts" /id="U3040" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.699300699300699" /psig=1 /xcortree=3153 /SigmaFactorBS="gctgtttttttataggtcagttttccctctagtcctccggat gttCATTGACTtgccattctctccaTTATAGAATTTATATACAtttcgcatcccttca t" /listShort="licR" /listLong="licB, licC, licA, licH" promotor_-35 complement(3829631..3829638) /Source="Nicolas_upshift_promotors" /id="U3040" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.699300699300699" /psig=1 /xcortree=3153 /SigmaFactorBS="gctgtttttttataggtcagttttccctctagtcctccggat gttCATTGACTtgccattctctccaTTATAGAATTTATATACAtttcgcatcccttca t" /listShort="licR" /listLong="licB, licC, licA, licH" /label="promotor_-35" CDS complement(3829689..3829847) /gene="yxzF" /locus_tag="BSU_38610" /old_locus_tag="BSU38610" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_391740.1" /db_xref="EnsemblGenomes-Gn:BSU38610" /db_xref="EnsemblGenomes-Tr:CAB15887" /db_xref="SubtiList:BG14169" /db_xref="UniProtKB/Swiss-Prot:O32283" /translation="MVEKKEGRIGALKKMIKTVIKWAPVIYPIVRKIMKDRKASKQKN MSASRTAG*" gene complement(3829689..3829847) /gene="yxzF" /locus_tag="BSU_38610" /old_locus_tag="BSU38610" downshifts complement(3829716) /Source="Nicolas_upshifts" /id="D2002" /incds=0 /nref=75 /ntot=208 /MaxReadThrough="0.739420000000001" /MaxDrop="6.4099" /score="27.6067633" /energy="-11.1" /TU="NA" /idTUdmin="U3041" /TUdmin="-3" /isTUend="TRUE" CDS complement(3829876..3830466) /gene="aag" /locus_tag="BSU_38620" /old_locus_tag="BSU38620" /EC_number="3.2.2.-" /function="16.6: Maintain" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:14729667, 27698084" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 14729667, 27698084; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="3-alkylated purines and hypoxanthine DNA glycosidase" /protein_id="NP_391741.1" /db_xref="EnsemblGenomes-Gn:BSU38620" /db_xref="EnsemblGenomes-Tr:CAB15888" /db_xref="GOA:P94378" /db_xref="InterPro:IPR003180" /db_xref="InterPro:IPR011034" /db_xref="InterPro:IPR036995" /db_xref="SubtiList:BG12555" /db_xref="UniProtKB/Swiss-Prot:P94378" /translation="MTREKNPLPITFYQKTALELAPSLLGCLLVKETDEGTASGYIVE TEAYMGAGDRAAHSFNNRRTKRTEIMFAEAGRVYTYVMHTHTLLNVVAAEEDVPQAVL IRAIEPHEGQLLMEERRPGRSPREWTNGPGKLTKALGVTMNDYGRWITEQPLYIESGY TPEAISTGPRIGIDNSGEARDYPWRFWVTGNRYVSR*" gene complement(3829876..3830466) /gene="aag" /locus_tag="BSU_38620" /old_locus_tag="BSU38620" promotor_-10 complement(3830494..3830512) /Source="Nicolas_upshift_promotors" /id="U3041" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.921078921078921" /psig="0.921078921078921" /xcortree=132 /SigmaFactorBS="aatattccctgaatggaaagattttaaaacagcCGTTTTTtt tgatctgcttcGGGAATGGTACAATGTACAaaaatcggtaaaaggagaggtcgattcg t" /listShort="aag, yxzF" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3830505) /Source="Nicolas_upshifts" /id="U3041" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.921078921078921" /psig="0.921078921078921" /xcortree=132 /SigmaFactorBS="aatattccctgaatggaaagattttaaaacagcCGTTTTTtt tgatctgcttcGGGAATGGTACAATGTACAaaaatcggtaaaaggagaggtcgattcg t" /listShort="aag, yxzF" /GFF_Attribute="listLong" promotor_-35 complement(3830526..3830532) /Source="Nicolas_upshift_promotors" /id="U3041" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.921078921078921" /psig="0.921078921078921" /xcortree=132 /SigmaFactorBS="aatattccctgaatggaaagattttaaaacagcCGTTTTTtt tgatctgcttcGGGAATGGTACAATGTACAaaaatcggtaaaaggagaggtcgattcg t" /listShort="aag, yxzF" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 3830535..3830541 /Source="Nicolas_upshift_promotors" /id="U3042" /multdbtbs="SigB,SigF" /comp="M11" /sig="SigB" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=727 /SigmaFactorBS="ttgtaccattcccgaagcagatcaaaaaaaacggcTGTTTTA aaatctttccattcaGGGAATATTGTTACCGTTCaaaaaaggagggccaaccattgaa a" /listShort="katX" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3830557..3830575 /Source="Nicolas_upshift_promotors" /id="U3042" /multdbtbs="SigB,SigF" /comp="M11" /sig="SigB" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=727 /SigmaFactorBS="ttgtaccattcccgaagcagatcaaaaaaaacggcTGTTTTA aaatctttccattcaGGGAATATTGTTACCGTTCaaaaaaggagggccaaccattgaa a" /listShort="katX" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3830560 /Source="Nicolas_upshifts" /id="U3042" /multdbtbs="SigB,SigF" /comp="M11" /sig="SigB" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=727 /SigmaFactorBS="ttgtaccattcccgaagcagatcaaaaaaaacggcTGTTTTA aaatctttccattcaGGGAATATTGTTACCGTTCaaaaaaggagggccaaccattgaa a" /listShort="katX" /GFF_Attribute="listLong" CDS 3830595..3832238 /gene="katX" /locus_tag="BSU_38630" /old_locus_tag="BSU38630" /EC_number="1.11.1.6" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:9393707, 9555886, 10503549, 24123749" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9393707, 9555886, 10503549, 24123749; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="major catalase in spores" /protein_id="NP_391742.1" /db_xref="EnsemblGenomes-Gn:BSU38630" /db_xref="EnsemblGenomes-Tr:CAB15889" /db_xref="GOA:P94377" /db_xref="InterPro:IPR002226" /db_xref="InterPro:IPR010582" /db_xref="InterPro:IPR011614" /db_xref="InterPro:IPR018028" /db_xref="InterPro:IPR020835" /db_xref="InterPro:IPR024708" /db_xref="InterPro:IPR024711" /db_xref="InterPro:IPR037060" /db_xref="SubtiList:BG11945" /db_xref="UniProtKB/Swiss-Prot:P94377" /translation="MKDDHQNKQHQSNAQGSEEAFSHKTSGKNESEDTLTNRQGHPVT DNQNVRTVGNRGPTTLENYDFLEKISHFDRERIPERVVHARGAGAHGYFEAYGSFGDE PISTYTRAKLFQEKGKKTPAFVRFSTVNHGKHSPETLRDPRGFAVKLYTEDGNWDLVG NNLKIFFIRDPLKFPDLVHAFQPDPVTNIQDGERIFDFISQSPEATHMITFLFSPWGI PANYRQMQGSGVHAYKWVNEEGKAVLVKYHFEPKQGIRNLTQKEAEEIQGKNFNHATQ DLYDAIENGDYPEWEVYAQIMSDDEHPELDFDPLDPTKLWYKDDFPWKPIGKLVLNKN PENYHAEVEQASFGTGVLVDGLDFSDDKLLQGRTFAYSDTQRYRVGANYLQLPINSPK KHVATNQEGGQMQYRVDRAEGQNPHVNYEPSIMGGLKEAKQDGKDHTPHVEGDVKREA IDRTNNFGQAGETYRRFTEFERNELITNLVNTLSTCRKEIQDQMIENFTKADPDYGKR VAEGLKKVSENNSNGPIGTTETEQAAKQAEQESHPSDPY*" gene 3830595..3832238 /gene="katX" /locus_tag="BSU_38630" /old_locus_tag="BSU38630" S_feature complement(3830732..3832281) /Source="Nicolas_S_feature" /locus_tag="new_3965134_3966683_c" /HighExp="T0.30H, T1.0H, T1.30H, T2.0H, T2.30H, T3.0H, S8, T3.30H, S6, T0.0H" /AntisenseName="katX" /AntisenseCor="0.28909015498211399" /AntisenseRegPval="-5.8" /CDS_PredictionProba="NA" /TUshortSig="SigWXY" /TUshortPSig="0.998" /TUlongSig="NA" /TUlongPSig="NA" /label="S1482" downshifts 3832233 /Source="Nicolas_upshifts" /id="D2003" /incds=0 /nref=28 /ntot=49 /MaxReadThrough="0.942820000000001" /MaxDrop="5.69337" /score="45.0252072" /energy="-12.7" /TU="NA" /idTUdmin="U3042" /TUdmin=0 /isTUend="TRUE" S_feature complement(3832283..3832374) /Source="Nicolas_S_feature" /locus_tag="new_3966685_3966776_c" /HighExp="T0.30H, T1.30H, T1.0H, T2.0H, T2.30H, T3.30H, T4.0H, T3.0H, T0.0H, T5.0H" /AntisenseName="yxlH" /AntisenseCor="-4.8005444617814199E-3" /AntisenseRegPval=0 /CDS_PredictionProba="NA" /TUshortSig="SigWXY" /TUshortPSig="0.998" /TUlongSig="NA" /TUlongPSig="NA" /label="S1483" promotor_-35 3832285..3832291 /Source="Nicolas_upshift_promotors" /id="U3043" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.45954045954046" /psig="0.914085914085914" /xcortree=1556 /SigmaFactorBS="caacagcgaacagggcttttttagaagccctgtttttttatt tttcTATTGAAacgctttcaataatTGTGTTGTACTTGGAAGGAAaggggtggagaga t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 3832299 /Source="Nicolas_upshifts" /id="U3043" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.45954045954046" /psig="0.914085914085914" /xcortree=1556 /SigmaFactorBS="caacagcgaacagggcttttttagaagccctgtttttttatt tttcTATTGAAacgctttcaataatTGTGTTGTACTTGGAAGGAAaggggtggagaga t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 3832306..3832325 /Source="Nicolas_upshift_promotors" /id="U3043" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.45954045954046" /psig="0.914085914085914" /xcortree=1556 /SigmaFactorBS="caacagcgaacagggcttttttagaagccctgtttttttatt tttcTATTGAAacgctttcaataatTGTGTTGTACTTGGAAGGAAaggggtggagaga t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" downshifts complement(3832326) /Source="Nicolas_upshifts" /id="D2004" /incds=0 /nref=8 /ntot=42 /MaxReadThrough="3.81662" /MaxDrop="3.1285" /score="-7.60062702" /energy="-7.5" /TU="U3045" /idTUdmin="U3045" /TUdmin="-1557" /isTUend="FALSE" CDS 3832343..3833545 /gene="yxlH" /locus_tag="BSU_38640" /old_locus_tag="BSU38640" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 14769884, 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative transporter" /protein_id="NP_391743.1" /db_xref="EnsemblGenomes-Gn:BSU38640" /db_xref="EnsemblGenomes-Tr:CAB15890" /db_xref="GOA:P94376" /db_xref="InterPro:IPR001958" /db_xref="InterPro:IPR011701" /db_xref="InterPro:IPR020846" /db_xref="InterPro:IPR036259" /db_xref="SubtiList:BG12554" /db_xref="UniProtKB/Swiss-Prot:P94376" /translation="MELQQDLIPQKKTIGALDHAVFLCMVFCFWFSGYIYVPVFSLYL EDLHFSYGAIGIILGSYGVTQILLRFPLGLLSDILFSLRKQLLIAGFGFSVLSSLLFL MFDSFFFVLAARLFAGITASTWVMATILYAHYFNNGNASKAMGIMQFFTVMPQFASIV FCGLAAAHLGRQVPFWMALAASAAGLVICCFIQDPSAPPANRGTIRVNQYIKDTLRLP KLKLFTILSMTAHAVLFITVFGFTPLYMNQLGMGDAELLWVMSAFFLPHAAATLSFVF LRFTSRIAYSVMLISFAVTGVCLLYVPFLAALFTVCITHACIGLALGFVFPLLLSHVV EISSARLKMSVMGFYQSFYALGIFLGPLLAGKIAQLIGLAGVFYGAGSLAFAAFFVML AQKRNMIN*" gene 3832343..3833545 /gene="yxlH" /locus_tag="BSU_38640" /old_locus_tag="BSU38640" S_feature complement(3832376..3833541) /Source="Nicolas_S_feature" /locus_tag="new_3966778_3967943_c" /HighExp="T1.0H, T1.30H, T0.30H, T2.0H, T2.30H, T0.0H, T3.0H, T3.30H, T-0.40H, T4.0H" /AntisenseName="yxlH" /AntisenseCor="-4.5703316381945601E-2" /AntisenseRegPval="-0.3" /CDS_PredictionProba="NA" /TUshortSig="SigWXY" /TUshortPSig="0.998" /TUlongSig="NA" /TUlongPSig="NA" /label="S1484" downshifts complement(3832419) /Source="Nicolas_upshifts" /id="D2005" /incds=1 /nref=3 /ntot=61 /MaxReadThrough="6.44992" /MaxDrop="2.92619" /score="-7.60062702" /energy="-7.5" /TU="U3045" /idTUdmin="U3045" /TUdmin="-1650" /isTUend="FALSE" CDS complement(3833542..3834318) /gene="yxlG" /locus_tag="BSU_38650" /old_locus_tag="BSU38650" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 14769884, 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative ABC-transporter (permease)" /protein_id="NP_391744.2" /db_xref="EnsemblGenomes-Gn:BSU38650" /db_xref="EnsemblGenomes-Tr:CAB15891" /db_xref="GOA:P94375" /db_xref="InterPro:IPR032688" /db_xref="SubtiList:BG12553" /db_xref="UniProtKB/Swiss-Prot:P94375" /translation="MKVMMALLQKEWLEGWKSGKLIWLPIAMMIVGLTQPLTIYYMPE IIAHGGNLPDGMKISFTMPSGSEVMVSTLSQFNTLGMALVIFSVMGSVANERNQGVTA LIMSRPVTAAHYIVSKWLIQSVIGIMSFAAGYGLAYYYVRLLFEDASFSRFAASLGLY ALWVIFIVTAGLAGSTIFRSVGAAAACGIGLTAAVSFAVSLFPDGAKWLPAEICKQAE HILLHGERADFFGWSLTFSILCIMLLAVFSVWRFRRYESY*" gene complement(3833542..3834318) /gene="yxlG" /locus_tag="BSU_38650" /old_locus_tag="BSU38650" CDS complement(3834315..3835202) /gene="yxlF" /locus_tag="BSU_38660" /old_locus_tag="BSU38660" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 12897008, 14769884, 14993308; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative ABC transporter component (ATP-binding protein)" /protein_id="NP_391745.1" /db_xref="EnsemblGenomes-Gn:BSU38660" /db_xref="EnsemblGenomes-Tr:CAB15892" /db_xref="GOA:P94374" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR017871" /db_xref="InterPro:IPR025302" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG12552" /db_xref="UniProtKB/Swiss-Prot:P94374" /translation="MLSIESLCKSYRHHEAVKNVSFHVNENECVALLGPNGAGKTTTL QMLAGLLSPTSGTIKLLGEKKLDRRLIGYLPQYPAFYSWMTANEFLTFAGRLSGLSKR KCQEKIGEMLEFVGLHEAAHKRIGGYSGGMKQRLGLAQALLHKPKFLILDEPVSALDP TGRFEVLDMMRELKKHMAVLFSTHVLHDAEQVCDQVVIMKNGEISWKGELQELKQQQQ TNVFTLSVKEKLEGWLEEKPYVSAIVYKNPSQAVFELPDIHAGRSLLSDCIRKGLTVT RFEQKTESLEDVYLKVVHA*" gene complement(3834315..3835202) /gene="yxlF" /locus_tag="BSU_38660" /old_locus_tag="BSU38660" CDS complement(3835209..3835397) /gene="yxlE" /locus_tag="BSU_38670" /old_locus_tag="BSU38670" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:12897008, 14769884, 14993308" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12897008, 14769884, 14993308; Product type r: regulator" /codon_start=1 /transl_table=11 /product="negative regulator of sigma-Y activity" /protein_id="NP_391746.1" /db_xref="EnsemblGenomes-Gn:BSU38670" /db_xref="EnsemblGenomes-Tr:CAB15893" /db_xref="GOA:P94373" /db_xref="InterPro:IPR027379" /db_xref="SubtiList:BG12551" /db_xref="UniProtKB/Swiss-Prot:P94373" /translation="MNISWEMILPLIVLQLALAVFALISCIKEERTNGPKWMWAAIIV CINIIGPILFFTVGRKQR*" gene complement(3835209..3835397) /gene="yxlE" /locus_tag="BSU_38670" /old_locus_tag="BSU38670" CDS complement(3835394..3835600) /gene="yxlD" /locus_tag="BSU_38680" /old_locus_tag="BSU38680" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 12897008, 14769884, 14993308; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative sigma-Y antisigma factor component" /protein_id="NP_391747.1" /db_xref="EnsemblGenomes-Gn:BSU38680" /db_xref="EnsemblGenomes-Tr:CAB15894" /db_xref="GOA:P94372" /db_xref="SubtiList:BG12550" /db_xref="UniProtKB/Swiss-Prot:P94372" /translation="MTQTEIIITVAACLIVLAQGIFLFIDAKKRNHMAWVWGIVGLIQ APMPLICYYFFVIRPDRKKRGIKQ*" gene complement(3835394..3835600) /gene="yxlD" /locus_tag="BSU_38680" /old_locus_tag="BSU38680" CDS complement(3835597..3835917) /gene="yxlC" /locus_tag="BSU_38690" /old_locus_tag="BSU38690" /function="16.12: Sense" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:12897008, 14769884, 14993308" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12897008, 14769884, 14993308; Product type r: regulator" /codon_start=1 /transl_table=11 /product="sigma-Y antisigma factor" /protein_id="NP_391748.1" /db_xref="EnsemblGenomes-Gn:BSU38690" /db_xref="EnsemblGenomes-Tr:CAB15895" /db_xref="GOA:P94371" /db_xref="InterPro:IPR035238" /db_xref="SubtiList:BG12549" /db_xref="UniProtKB/Swiss-Prot:P94371" /translation="MNKEKLSDHLKSEWKKIDQTANPSIPNQKELLHQLSQMKAEYRK KLLQEIILFVFCALMVVSAAILAFTQAPAVFIVLQVCVLAVLPILIAAEKKRHLGECE VKRG*" gene complement(3835597..3835917) /gene="yxlC" /locus_tag="BSU_38690" /old_locus_tag="BSU38690" promotor_-35 3835730..3835739 /Source="Nicolas_upshift_promotors" /id="U3044" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=1366 /SigmaFactorBS="aacacagcaggagcttgagtgaaagctaagattgcaGCACTC ACAAccatcagcgcgcAGAATACAAATAAAATGATCtcttgaagaagtttttttctgt a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3835752..3835771 /Source="Nicolas_upshift_promotors" /id="U3044" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=1366 /SigmaFactorBS="aacacagcaggagcttgagtgaaagctaagattgcaGCACTC ACAAccatcagcgcgcAGAATACAAATAAAATGATCtcttgaagaagtttttttctgt a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3835754 /Source="Nicolas_upshifts" /id="U3044" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=1366 /SigmaFactorBS="aacacagcaggagcttgagtgaaagctaagattgcaGCACTC ACAAccatcagcgcgcAGAATACAAATAAAATGATCtcttgaagaagtttttttctgt a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" CDS complement(3835910..3836446) /gene="sigY" /locus_tag="BSU_38700" /old_locus_tag="BSU38700" /function="16.12: Sense" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:12897008, 14769884, 14993308" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12897008, 14769884, 14993308; Product type r: regulator" /codon_start=1 /transl_table=11 /product="RNA polymerase ECF (extracytoplasmic function)-type sigma factor (sigma-Y)" /protein_id="NP_391749.1" /db_xref="EnsemblGenomes-Gn:BSU38700" /db_xref="EnsemblGenomes-Tr:CAB15896" /db_xref="GOA:P94370" /db_xref="InterPro:IPR000838" /db_xref="InterPro:IPR007627" /db_xref="InterPro:IPR013249" /db_xref="InterPro:IPR013324" /db_xref="InterPro:IPR013325" /db_xref="InterPro:IPR014284" /db_xref="InterPro:IPR036388" /db_xref="SubtiList:BG11975" /db_xref="UniProtKB/Swiss-Prot:P94370" /translation="MDTQEEQRLIQQAKEGNDEAFTALFHYHYSFLYKYLLKLSLHPD LSEELVQETFLKGYIHLRSFQGRSKFSTWLISIASRLYLDHQKKRKREWKRNQTVTEE TIRKIKWDVSAKGAEWSETLDLFSKLDPKLRTPVLLRHYYGYTYAEIGVMLQIKEGTV KSRVHKGLQQIRKEWDDE*" gene complement(3835910..3836446) /gene="sigY" /locus_tag="BSU_38700" /old_locus_tag="BSU38700" upshifts complement(3836474) /Source="Nicolas_upshifts" /id="U3045" /multdbtbs="SigY" /comp="M9" /sig="SigWXY" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=1710 /SigmaFactorBS="gctgaaaagaattgtaaaaaagaTGAACGCTTTtgaatccgg tgTCGTCTCATAAGGCAGaaaaacaaaaaaggggggatcacggtcattggatacacaa g" /listShort="sigY, yxlC, yxlD, yxlE, yxlF, yxlG, S1484, S1483, S1482" /GFF_Attribute="listLong" promotor_-10 complement(3836475..3836490) /Source="Nicolas_upshift_promotors" /id="U3045" /multdbtbs="SigY" /comp="M9" /sig="SigWXY" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=1710 /SigmaFactorBS="gctgaaaagaattgtaaaaaagaTGAACGCTTTtgaatccgg tgTCGTCTCATAAGGCAGaaaaacaaaaaaggggggatcacggtcattggatacacaa g" /listShort="sigY, yxlC, yxlD, yxlE, yxlF, yxlG, S1484, S1483, S1482" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 complement(3836502..3836511) /Source="Nicolas_upshift_promotors" /id="U3045" /multdbtbs="SigY" /comp="M9" /sig="SigWXY" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=1710 /SigmaFactorBS="gctgaaaagaattgtaaaaaagaTGAACGCTTTtgaatccgg tgTCGTCTCATAAGGCAGaaaaacaaaaaaggggggatcacggtcattggatacacaa g" /listShort="sigY, yxlC, yxlD, yxlE, yxlF, yxlG, S1484, S1483, S1482" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 3836577..3836584 /Source="Nicolas_upshift_promotors" /id="U3046" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.655344655344655" /psig="0.993006993006993" /xcortree=2429 /SigmaFactorBS="aggcttcccggccgtttggctgcatatcctTATTTGTAaacc cccttatagTCTGTTAAGCTATGACTTTAtgtcgatttcaaaaaaacatccaatatgg a" /listShort="yxlA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3836598..3836617 /Source="Nicolas_upshift_promotors" /id="U3046" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.655344655344655" /psig="0.993006993006993" /xcortree=2429 /SigmaFactorBS="aggcttcccggccgtttggctgcatatcctTATTTGTAaacc cccttatagTCTGTTAAGCTATGACTTTAtgtcgatttcaaaaaaacatccaatatgg a" /listShort="yxlA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3836607 /Source="Nicolas_upshifts" /id="U3046" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.655344655344655" /psig="0.993006993006993" /xcortree=2429 /SigmaFactorBS="aggcttcccggccgtttggctgcatatcctTATTTGTAaacc cccttatagTCTGTTAAGCTATGACTTTAtgtcgatttcaaaaaaacatccaatatgg a" /listShort="yxlA" /GFF_Attribute="listLong" CDS 3836658..3838031 /gene="yxlA" /locus_tag="BSU_38710" /old_locus_tag="BSU38710" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 2191181, 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative purine-cytosine (pyridoxine) permease" /protein_id="NP_391750.1" /db_xref="EnsemblGenomes-Gn:BSU38710" /db_xref="EnsemblGenomes-Tr:CAB15897" /db_xref="GOA:P94369" /db_xref="InterPro:IPR001248" /db_xref="InterPro:IPR026030" /db_xref="SubtiList:BG12548" /db_xref="UniProtKB/Swiss-Prot:P94369" /translation="MKVERRTIEYIPNEERHGKAKDLFPVWFGANMHITTLVTGTIPV AMGLNLFWSVAAIICGTLIGAIFMASHSAQGPQLGIPQMIQSRAQFGVIGAILPLFLV MFIYLGFFASSTILAAGTLSSFVPIPGSWSIIGLSAVCFLLTIFGHDLIHKMQKILSW TSFAVFFAATILIFQLPIPAGSWIPGAIDLPIFLVAVSAVATWQLAYAPYVADYSRYL PVKTPASKTFWYSYAGTSVSSIWMMLLGALLTTSLPDFTANSGSQIVQLFGPFSFIML IIVLFGQMAINVFNLYGAFMSTTTTLEPFLKLKVTPKVRIIMILGVTLVGTVLSLLGQ SNFMELFLNFIFFISYFLIPWTAINLVDYYFVRHGKYQVKAMFDVNGPYGKVNWITTI AFVLSILLEIPFINTSFYIGPLAKMFGGGDIAWIIGLAVPSVLYYVLMKPRLKKRAGY QEKLSSL*" gene 3836658..3838031 /gene="yxlA" /locus_tag="BSU_38710" /old_locus_tag="BSU38710" S_feature complement(3836938..3837480) /Source="Nicolas_S_feature" /locus_tag="new_3971340_3971882_c" /HighExp="Etha, LBGstat, T1.0H, T0.30H, Diami, T1.30H, dia15, G150, G135, G180" /AntisenseName="yxlA" /AntisenseCor="-8.6586358833710395E-2" /AntisenseRegPval="-0.8" /CDS_PredictionProba="NA" /TUshortSig="SigB" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1485" promotor_-10 complement(3837468..3837487) /Source="Nicolas_upshift_promotors" /id="U3047" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.98101898101898" /psig="0.996003996003996" /xcortree=1813 /SigmaFactorBS="aagccccatacaggttaaaaacattgattgcCATTTGCCcaa atagcacaatgATCAGCATAATAAACGAGAAgggaccgaacaattggacaatctggct g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3837480) /Source="Nicolas_upshifts" /id="U3047" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.98101898101898" /psig="0.996003996003996" /xcortree=1813 /SigmaFactorBS="aagccccatacaggttaaaaacattgattgcCATTTGCCcaa atagcacaatgATCAGCATAATAAACGAGAAgggaccgaacaattggacaatctggct g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(3837502..3837509) /Source="Nicolas_upshift_promotors" /id="U3047" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.98101898101898" /psig="0.996003996003996" /xcortree=1813 /SigmaFactorBS="aagccccatacaggttaaaaacattgattgcCATTTGCCcaa atagcacaatgATCAGCATAATAAACGAGAAgggaccgaacaattggacaatctggct g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 3837866 /Source="Nicolas_upshifts" /id="D2006" /incds=1 /nref=30 /ntot=136 /MaxReadThrough="1.87017" /MaxDrop="3.59478" /score="22.3054019" /energy="-12.9" /TU="NA" /idTUdmin="U3046" /TUdmin=0 /isTUend="TRUE" CDS complement(3838046..3838876) /gene="nnrA" /locus_tag="BSU_38720" /old_locus_tag="BSU38720" /function="16.8: Protect" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:12457846, 21994945, 22940582, 25393291" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12457846, 21994945, 22940582, 25393291; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="NAD(P)H dehydratase" /protein_id="NP_391751.1" /db_xref="EnsemblGenomes-Gn:BSU38720" /db_xref="EnsemblGenomes-Tr:CAB15898" /db_xref="GOA:P94368" /db_xref="InterPro:IPR000631" /db_xref="InterPro:IPR017953" /db_xref="InterPro:IPR029056" /db_xref="PDB:1KYH" /db_xref="PDB:3RPH" /db_xref="PDB:3RPZ" /db_xref="PDB:3RQ2" /db_xref="PDB:3RQ5" /db_xref="PDB:3RQ6" /db_xref="PDB:3RQ8" /db_xref="PDB:3RQH" /db_xref="PDB:3RQQ" /db_xref="PDB:3RQX" /db_xref="SubtiList:BG12547" /db_xref="UniProtKB/Swiss-Prot:P94368" /translation="MNVPFWTEEHVRATLPERDAESHKGTYGTALLLAGSDDMPGAAL LAGLGAMRSGLGKLVIGTSENVIPLIVPVLPEATYWRDGWKKAADAQLEETYRAIAIG PGLPQTESVQQAVDHVLTADCPVILDAGALAKRTYPKREGPVILTPHPGEFFRMTGVP VNELQKKRAEYAKEWAAQLQTVIVLKGNQTVIAFPDGDCWLNPTGNGALAKGGTGDTL TGMILGMLCCHEDPKHAVLNAVYLHGACAELWTDEHSAHTLLAHELSDILPRVWKRFE *" gene complement(3838046..3838876) /gene="nnrA" /locus_tag="BSU_38720" /old_locus_tag="BSU38720" downshifts complement(3838052) /Source="Nicolas_upshifts" /id="D2007" /incds=0 /nref=3 /ntot=52 /MaxReadThrough="3.50755" /MaxDrop="3.84264" /score="7.61210868" /energy="-12.9" /TU="U3048" /idTUdmin="U3051" /TUdmin=792 /isTUend="FALSE" promotor_-10 complement(3838895..3838913) /Source="Nicolas_upshift_promotors" /id="U3048" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=168 /SigmaFactorBS="gtaaaataaaagacagccctaaaaggctgtctttttTGTTTG AaaaagaaaagggacAGGAAAAATAGGAAAAGAAagcagaggagggatagagatgaat g" /listShort="yxkO, S1485" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3838910) /Source="Nicolas_upshifts" /id="U3048" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=168 /SigmaFactorBS="gtaaaataaaagacagccctaaaaggctgtctttttTGTTTG AaaaagaaaagggacAGGAAAAATAGGAAAAGAAagcagaggagggatagagatgaat g" /listShort="yxkO, S1485" /GFF_Attribute="listLong" promotor_-35 complement(3838928..3838934) /Source="Nicolas_upshift_promotors" /id="U3048" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=168 /SigmaFactorBS="gtaaaataaaagacagccctaaaaggctgtctttttTGTTTG AaaaagaaaagggacAGGAAAAATAGGAAAAGAAagcagaggagggatagagatgaat g" /listShort="yxkO, S1485" /GFF_Attribute="listLong" /label="promotor_-35" upshifts complement(3838954) /Source="Nicolas_upshifts" /id="U3049" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.973026973026973" /psig="0.98101898101898" /xcortree=2119 /SigmaFactorBS="cggcaaacgaacgatatcgccgcctgtatcaccttgatgTTC CTGTAAAATAAAAGACAgccctaaaaggctgtcttttttgtttgaaaaagaaaaggga c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" misc_feature complement(3838956..3838975) /Source="Nicolas_upshift_promotors" /id="U3049" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.973026973026973" /psig="0.98101898101898" /xcortree=2119 /SigmaFactorBS="cggcaaacgaacgatatcgccgcctgtatcaccttgatgTTC CTGTAAAATAAAAGACAgccctaaaaggctgtcttttttgtttgaaaaagaaaaggga c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" CDS complement(3838962..3840689) /gene="cydD" /locus_tag="BSU_38730" /old_locus_tag="BSU38730" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 9852001, 10551842, 15231791, 16040611, 26517902, 26699904; Product type t : transporter" /codon_start=1 /transl_table=11 /product="ABC membrane transporter (ATP-binding protein) required for cytochrome bb' function (reductant efflux pump)" /protein_id="NP_391752.1" /db_xref="EnsemblGenomes-Gn:BSU38730" /db_xref="EnsemblGenomes-Tr:CAB15899" /db_xref="GOA:P94367" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR011527" /db_xref="InterPro:IPR014223" /db_xref="InterPro:IPR017871" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR036640" /db_xref="SubtiList:BG11928" /db_xref="UniProtKB/Swiss-Prot:P94367" /translation="MKKEEWILPYIKQNARLFVLVIFLGAVTIFSAAFLMFTSGFLIS KAATRPENILLIYVPIVAVRTFGIARSVSRYVERLVGHHIILKIVSDMRVRLYNMLEP GALMLRSRFRTGDMLGILSEDIEHLQDAFLKTIFPAISALLLYAVSVIALGFFSWPFA ILLALYLFVLVVLFPVVSLLVTRAKNAKLKSGRNVLYSRLTDAVMGVSDWMFSGRRHA FIDAYEKEERDWFELERKKQRFTRWRDFAAQCLVAGLILLMLFWTAGQQADGELAKTM IAAFVLVVFPLTEAFLPLSDALGEVPGYQDSIRRMNNVAPQPEASQTESGDQILDLQD VTLAFRDVTFSYDNSSQVLHNFSFTLRQGEKMALLGRSGSGKSTSLALIEGALKPDSG SVTLNGVETALLKDQIADAVAVLNQKPHLFDTSILNNIRLGNGEASDEDVRRAAKQVK LHDYIESLPDGYHTSVQETGIRFSGGERQRIALARILLQDTPIIILDEPTVGLDPITE RELMETVFEVLKGKTILWITHHLAGVEAADKIVFLENGKTEMEGTHEELLAANERYRR LYHLDVPVK*" gene complement(3838962..3840689) /gene="cydD" /locus_tag="BSU_38730" /old_locus_tag="BSU38730" downshifts complement(3839061) /Source="Nicolas_upshifts" /id="D2008" /incds=1 /nref=7 /ntot=46 /MaxReadThrough="5.39758" /MaxDrop="3.66431" /score="25.0271963" /energy="-10.6" /TU="U3051" /idTUdmin="U3051" /TUdmin="-217" /isTUend="FALSE" CDS complement(3840686..3842389) /gene="cydC" /locus_tag="BSU_38740" /old_locus_tag="BSU38740" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 9852001, 10551842, 15231791, 16040611, 26517902, 26699904; Product type t : transporter" /codon_start=1 /transl_table=11 /product="ABC membrane transporter (ATP-binding protein) required for cytochrome bb' function (reductant efflux pump)" /protein_id="NP_391753.1" /db_xref="EnsemblGenomes-Gn:BSU38740" /db_xref="EnsemblGenomes-Tr:CAB15900" /db_xref="GOA:P94366" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR011527" /db_xref="InterPro:IPR014216" /db_xref="InterPro:IPR017871" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR036640" /db_xref="SubtiList:BG11927" /db_xref="UniProtKB/Swiss-Prot:P94366" /translation="MGKDLFRYKGMKRILTLITCLTLIQTAAIIMQAEWLSEAVTGLF NGKGITSLLPVIGFFLIAFIARHGMTVARQKIVYQYAARTGADLRKSFLDQLFRLGPR FAKKEGTGQMVTLAMEGISQFRRYLELFLPKMVSMAIVPAAVVIYVFFQDRTSAIILV AAMPILIIFMILLGLVAQRKADRQWKSYQRLSNHFVDSLRGLETLRFLGLSKSHSKNI FYVSERYRKATMSTLRVAFLSSFALDFFTMLSVATVAVFLGLRLIDGDILLGPALTAL ILAPEYFLPVREVGNDYHATLNGQEAGKTIQEILSQPGFKEETPLQLEAWSDQDELKL SGVSVGRSVSDIHLSFKGKKKIGIIGASGAGKSTLIDILGGFLEPDGGMIEVNGTSRS HLQDGSWQKNLLYIPQHPYIFDDTLGNNIRFYHPSASAEDTTRAAASAGLTELVNNLP DGLEGRIGEGGRALSGGQAQRVALARAFLGNRPILLLDEPTAHLDIETEYEIKETMLD LFEDKLVFLATHRLHWMLDMDEIIVLDGGRVAEIGTHNELLEKNGVYTKLVKAQLGER A*" gene complement(3840686..3842389) /gene="cydC" /locus_tag="BSU_38740" /old_locus_tag="BSU38740" CDS complement(3842389..3843405) /gene="cydB" /locus_tag="BSU_38750" /old_locus_tag="BSU38750" /EC_number="1.10.3.-" /function="16.10: Respire" /experiment="publication(s) with functional evidences, PMID:9852001, 10551842, 15231791, 15849754, 16850406" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9852001, 10551842, 15231791, 15849754, 16850406; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="cytochrome bb' ubiquinol oxidase (subunit II)" /protein_id="NP_391754.1" /db_xref="EnsemblGenomes-Gn:BSU38750" /db_xref="EnsemblGenomes-Tr:CAB15901" /db_xref="GOA:P94365" /db_xref="InterPro:IPR003317" /db_xref="SubtiList:BG11926" /db_xref="UniProtKB/Swiss-Prot:P94365" /translation="MASLHDLWFILVAVLFVGFFFLEGFDFGVGMATRFLGHNELERR VLINTIGPFWDANEVWLLTGAGAIFAAFPNWYATMLSGYYIPFVIVLLALMGRGVAFE FRGKVDHLKWVKVWDWVVFFGSLIPPFVLGVLFTTLFRGMPIDADMNIHAHVSDYINV YSILGGVTVTLLCFQHGLMFITLRTIGDLQNRARKMAQKIMGVVFVAVLAFAALSAYQ TDMFTRRGEITIPLAVLIVICFMLAAVFIRKKKDGWTFGMTGAGLALTVGMIFISLFP RVMVSSLHSAYDLTVANASSGDYSLKVMSIAALTLLPFVIGSQIWSYYVFRKRVSHKE PMTY*" gene complement(3842389..3843405) /gene="cydB" /locus_tag="BSU_38750" /old_locus_tag="BSU38750" promotor_-10 complement(3843279..3843297) /Source="Nicolas_upshift_promotors" /id="U3050" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.963036963036963" /psig="0.963036963036963" /xcortree=1107 /SigmaFactorBS="ttctttttggaaggctttgatttcggggtcGGCATGgcgacc cgttttcttGGCCATAATGAATTAGAACgcagagtgctgatcaacacgatcgggccgt t" /listShort="cydC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3843288) /Source="Nicolas_upshifts" /id="U3050" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.963036963036963" /psig="0.963036963036963" /xcortree=1107 /SigmaFactorBS="ttctttttggaaggctttgatttcggggtcGGCATGgcgacc cgttttcttGGCCATAATGAATTAGAACgcagagtgctgatcaacacgatcgggccgt t" /listShort="cydC" /GFF_Attribute="listLong" promotor_-35 complement(3843313..3843318) /Source="Nicolas_upshift_promotors" /id="U3050" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.963036963036963" /psig="0.963036963036963" /xcortree=1107 /SigmaFactorBS="ttctttttggaaggctttgatttcggggtcGGCATGgcgacc cgttttcttGGCCATAATGAATTAGAACgcagagtgctgatcaacacgatcgggccgt t" /listShort="cydC" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3843389..3844795) /gene="cydA" /locus_tag="BSU_38760" /old_locus_tag="BSU38760" /EC_number="1.10.3.-" /function="16.10: Respire" /experiment="publication(s) with functional evidences, PMID:9852001, 10551842, 15231791, 15849754, 16850406" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9852001, 10551842, 15231791, 15849754, 16850406; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="cytochrome bb' ubiquinol oxidase (subunit I)" /protein_id="NP_391755.1" /db_xref="EnsemblGenomes-Gn:BSU38760" /db_xref="EnsemblGenomes-Tr:CAB15902" /db_xref="GOA:P94364" /db_xref="InterPro:IPR002585" /db_xref="SubtiList:BG11925" /db_xref="UniProtKB/Swiss-Prot:P94364" /translation="MSELVLARIQFASTTLFHFLFVPMSIGLVFMVALMETLYLVKKN ELYLKMAKFWGHLFLINFAVGVVTGILQEFQFGLNWSDYSRFVGDVFGAPLAIEALLA FFMESIFIGLWIFGWDRLPKKIHALCIWLVSFGTIMSSFWILTANSFMQEPVGFTIKN GRAEMNDFGALITNPQLWVEFPHVIFGALATGAFFIAGVSAFKLLKKKEVPFFKQSFK LAMIVGLCAGLGVGLSGHMQAEHLMESQPMKMAASEGLWEDSGDPAAWTAFATIDTKN EKSSNEIKVPYALSYLAYQKFSGSVKGMKTLQAEYEKIYGKGDYIPPVKTTFWSFRIM VGAGVVMILAALGGLWLNRRKKLENSKWYLRIMIALISFPFLANSAGWIMTEIGRQPW TVMGLMTTAQSVSPNVTAGSLLFSIIAFGVMYMILGALLVFLFIREIKKGAEHDNHHD VPVSTDPFSQEVYHGISS*" gene complement(3843389..3844795) /gene="cydA" /locus_tag="BSU_38760" /old_locus_tag="BSU38760" S_feature complement(3844796..3845004) /Source="Nicolas_S_feature" /locus_tag="new_3979198_3979406_c" /HighExp="M0t45, ferm, UNK1, Gly, Lbexp, Lbstat, dia0, nit, M/G, M40t45" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="0.999, 0.996" /TUlongSig="NA" /TUlongPSig="NA" /label="S1486" promotor_-10 complement(3844987..3845006) /Source="Nicolas_upshift_promotors" /id="U3051" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.276723276723277" /psig="0.999000999001" /xcortree=1601 /SigmaFactorBS="aatccgtcacatagtgcgggactttttaggtattttaggCTT TATttttgaaatgaatCGTTGTAAAGTACTTAATATgaaccagtcagagattgtgtca t" /listShort="S1486, cydA, cydB, cydC, cydD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3845004) /Source="Nicolas_upshifts" /id="U3051" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.276723276723277" /psig="0.999000999001" /xcortree=1601 /SigmaFactorBS="aatccgtcacatagtgcgggactttttaggtattttaggCTT TATttttgaaatgaatCGTTGTAAAGTACTTAATATgaaccagtcagagattgtgtca t" /listShort="S1486, cydA, cydB, cydC, cydD" /GFF_Attribute="listLong" S_feature complement(3845006..3845114) /Source="Nicolas_S_feature" /locus_tag="new_3979408_3979516_c" /HighExp="LPhT, LBGtran, ferm, LBGstat, M0t45, dia0, Etha, dia5, Lbexp, B60" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.996" /TUlongSig="NA" /TUlongPSig="NA" /label="S1487" promotor_-35 complement(3845020..3845025) /Source="Nicolas_upshift_promotors" /id="U3051" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.276723276723277" /psig="0.999000999001" /xcortree=1601 /SigmaFactorBS="aatccgtcacatagtgcgggactttttaggtattttaggCTT TATttttgaaatgaatCGTTGTAAAGTACTTAATATgaaccagtcagagattgtgtca t" /listShort="S1486, cydA, cydB, cydC, cydD" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(3845111..3845130) /Source="Nicolas_upshift_promotors" /id="U3052" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.713286713286713" /psig="0.996003996003996" /xcortree=1598 /SigmaFactorBS="ctgagactcgagtgctggggcgggggcaagcatttTGTTCGC AaggaacgatgtgtTGATGTACGATAATAAAGGGtcatttatcctagcagccgacata a" /listShort="S1487, S1486, cydA" /listLong="cydB, cydC, cydD" /label="promotor_-10" upshifts complement(3845126) /Source="Nicolas_upshifts" /id="U3052" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.713286713286713" /psig="0.996003996003996" /xcortree=1598 /SigmaFactorBS="ctgagactcgagtgctggggcgggggcaagcatttTGTTCGC AaggaacgatgtgtTGATGTACGATAATAAAGGGtcatttatcctagcagccgacata a" /listShort="S1487, S1486, cydA" /listLong="cydB, cydC, cydD" promotor_-35 complement(3845144..3845151) /Source="Nicolas_upshift_promotors" /id="U3052" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.713286713286713" /psig="0.996003996003996" /xcortree=1598 /SigmaFactorBS="ctgagactcgagtgctggggcgggggcaagcatttTGTTCGC AaggaacgatgtgtTGATGTACGATAATAAAGGGtcatttatcctagcagccgacata a" /listShort="S1487, S1486, cydA" /listLong="cydB, cydC, cydD" /label="promotor_-35" promotor_-35 3845272..3845279 /Source="Nicolas_upshift_promotors" /id="U3053" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.65034965034965" /psig="0.997002997002997" /xcortree=400 /SigmaFactorBS="tttgaaccggtaagaggagaaaagttgaatagtaaattttta aTATATTAAtaatttcaatttttTAGTATACTTAACATAGTGaacaatttcactgcat c" /listShort="cimH, yxkI" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 3845289 /Source="Nicolas_upshifts" /id="U3053" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.65034965034965" /psig="0.997002997002997" /xcortree=400 /SigmaFactorBS="tttgaaccggtaagaggagaaaagttgaatagtaaattttta aTATATTAAtaatttcaatttttTAGTATACTTAACATAGTGaacaatttcactgcat c" /listShort="cimH, yxkI" /GFF_Attribute="listLong" promotor_-10 3845294..3845312 /Source="Nicolas_upshift_promotors" /id="U3053" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.65034965034965" /psig="0.997002997002997" /xcortree=400 /SigmaFactorBS="tttgaaccggtaagaggagaaaagttgaatagtaaattttta aTATATTAAtaatttcaatttttTAGTATACTTAACATAGTGaacaatttcactgcat c" /listShort="cimH, yxkI" /GFF_Attribute="listLong" /label="promotor_-10" CDS 3845351..3846703 /gene="cimH" /locus_tag="BSU_38770" /old_locus_tag="BSU38770" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:11566984, 12525174, 15849754, 16850406, 22720735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11566984, 12525174, 15849754, 16850406, 22720735; Product type t : transporter" /codon_start=1 /transl_table=11 /product="citrate/malate/H+ symporter" /protein_id="NP_391756.1" /db_xref="EnsemblGenomes-Gn:BSU38770" /db_xref="EnsemblGenomes-Tr:CAB15903" /db_xref="GOA:P94363" /db_xref="InterPro:IPR004679" /db_xref="InterPro:IPR018025" /db_xref="SubtiList:BG12546" /db_xref="UniProtKB/Swiss-Prot:P94363" /translation="MGELQTHMQLQTDTIHEGVRKENWFAKAMNIKVGIIPLPVYALL FILITVFVMHHDVKSDILTSIAVMAFFGFTFAQIGKSIPIVRSIGGPAILATFIPSAV VYYHLLPNDIVKSTTEFTENSNFLYLFIAGIVVGSILGMKRETLVKAFMKIFIPLIVG SVTAAIVGLAVGTLLGLGFQHTLLYIVIPIMAGGVGEGAIPLSIGYSDIMPISQGEAF ALVLPSIMLGSLCAIILAGLLNRIGKKKPEWTGNGKVDRSEEESPALEESQSGQQMFN LSLFASGGILAVSLYLVGMLAHDFFGFPAPVAMLLLAVLIKLFRLVPASIENGAFGVS RFFSTAVTYPLLFAIGVSMTPWDKLVAAFNLSNIITILSVVVTMMAVGFFTGKWLNMY PIETAIINACHSGQGGTGDVAILSAAERLELMPFAQVSTRIGGAITVSLTLLLLHQFY *" gene 3845351..3846703 /gene="cimH" /locus_tag="BSU_38770" /old_locus_tag="BSU38770" S_feature complement(3846302..3848784) /Source="Nicolas_S_feature" /locus_tag="new_3980704_3983186_c" /HighExp="Cold, C30, LBGstat, Paraq, GM 120, GM 90, H2O2, Oxctl, GM 25, GM 45" /AntisenseName="yxkI" /AntisenseCor="0.564471040461903" /AntisenseRegPval="-23.3" /CDS_PredictionProba="NA" /TUshortSig="SigD" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1488" downshifts 3846688 /Source="Nicolas_upshifts" /id="D2009" /incds=0 /nref=63 /ntot=147 /MaxReadThrough="2.93791" /MaxDrop="3.97692" /score="3.68725156" /energy="-12.7" /TU="U3053" /idTUdmin="U3053" /TUdmin="-220" /isTUend="FALSE" misc_feature 3846779..3846798 /Source="Nicolas_upshift_promotors" /id="U3054" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.892107892107892" /psig="0.999000999001" /xcortree=2291 /SigmaFactorBS="tcaaacgaaagagcttgcttttttgcatgtccatgtttttgc aagttcccatccCATGCTATAGTAATAGTTGGaaatactagatagaaaggaatctggc a" /listShort="yxkI" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 3846785 /Source="Nicolas_upshifts" /id="U3054" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.892107892107892" /psig="0.999000999001" /xcortree=2291 /SigmaFactorBS="tcaaacgaaagagcttgcttttttgcatgtccatgtttttgc aagttcccatccCATGCTATAGTAATAGTTGGaaatactagatagaaaggaatctggc a" /listShort="yxkI" /GFF_Attribute="listLong" CDS 3846825..3848513 /gene="yxkI" /locus_tag="BSU_38780" /old_locus_tag="BSU38780" /EC_number="3.4.24.-" /function="16.8: Protect" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 16845009; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative membrane protease" /protein_id="NP_391757.1" /db_xref="EnsemblGenomes-Gn:BSU38780" /db_xref="EnsemblGenomes-Tr:CAB15904" /db_xref="GOA:P94362" /db_xref="InterPro:IPR001915" /db_xref="SubtiList:BG12545" /db_xref="UniProtKB/Swiss-Prot:P94362" /translation="MPMGTHLFLFMLLGLGFYLISALAAKLIPAIDFWIDIVLWVGAA AYIFSHLSFMDGIVSLATMFYCYWTAMDLIVSERVEKPSGDWQEIELAKNKTRLLSDI TLTAIVFAGAVIFFIYGPDTSPLKYVILLGMISGGGALVKRILNVFSVKVFYSAALEK LHISSHYETRTYPLSDLKNIQLESTADLLKLHPLLTMYSSRLDLTTSFQQVIKLSLPG ETLFLTVKEPQKWKTILQEYTDAENNVDNVISVLPFYHRKNVKRLLGKLYFAASVKGV SAYALLVLALYALHASPWVMAVAVILYWVFNMYMSDRVLRAAMDAKSCHHPHVQAAAD KIFRSAGISHVRIYETESDDYNGMAVGMNVGRSMVILTSATLTLPQRVIEGILAHEAI HIKKRDVLSSQLLRFLYLGAVVGIFLLFEQHITHPEAHKIALWAFIMAIIILFQLYQS FCSQWMEVRADNLGASLLDGGYKQMAEALRILAVRQDEDIQKQSAYSSEAGEDELQID SLTRDKSWFFRLIDFQFAPHPPMYWRVGTLLSNKGHGVLKRWLRDRLKESITLK*" gene 3846825..3848513 /gene="yxkI" /locus_tag="BSU_38780" /old_locus_tag="BSU38780" promotor_-35 3848511..3848520 /Source="Nicolas_upshift_promotors" /id="U3055" /multdbtbs="SigW" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1699 /SigmaFactorBS="tcagagaccgactgaaagaatcgatcactttgaaaTGAAACC GGTcagcgtttcatCCGTATAACAGATATGgtgaaaaaagggagtgacgcgaagtgat t" /listShort="yxzE, S1489" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3848532..3848547 /Source="Nicolas_upshift_promotors" /id="U3055" /multdbtbs="SigW" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1699 /SigmaFactorBS="tcagagaccgactgaaagaatcgatcactttgaaaTGAAACC GGTcagcgtttcatCCGTATAACAGATATGgtgaaaaaagggagtgacgcgaagtgat t" /listShort="yxzE, S1489" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3848536 /Source="Nicolas_upshifts" /id="U3055" /multdbtbs="SigW" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1699 /SigmaFactorBS="tcagagaccgactgaaagaatcgatcactttgaaaTGAAACC GGTcagcgtttcatCCGTATAACAGATATGgtgaaaaaagggagtgacgcgaagtgat t" /listShort="yxzE, S1489" /GFF_Attribute="listLong" CDS 3848571..3848771 /gene="yxzE" /locus_tag="BSU_38790" /old_locus_tag="BSU38790" /function="16.5: Explore" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 16845009; Product type f: factor" /codon_start=1 /transl_table=11 /product="putative bacteriocin" /protein_id="NP_391758.1" /db_xref="EnsemblGenomes-Gn:BSU38790" /db_xref="EnsemblGenomes-Tr:CAB15905" /db_xref="SubtiList:BG14168" /db_xref="UniProtKB/Swiss-Prot:O32284" /translation="MIVIILLFISIIVFLSVIQPQPSKNKSRQQADSGYFGYSDHSSH HDGCSSDGGFSDSGCGGGGGGD*" gene 3848571..3848771 /gene="yxzE" /locus_tag="BSU_38790" /old_locus_tag="BSU38790" S_feature 3848772..3849716 /Source="Nicolas_S_feature" /locus_tag="new_3983174_3984118" /HighExp="T0.30H, T1.0H, T1.30H, T2.0H, T2.30H, T0.0H, T-0.40H, Salt, T3.30H, T3.0H" /AntisenseName="yxkH" /AntisenseCor="0.147753218660366" /AntisenseRegPval="-1.8" /CDS_PredictionProba="NA" /TUshortSig="SigWXY" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1489" CDS complement(3848785..3849624) /gene="yxkH" /locus_tag="BSU_38800" /old_locus_tag="BSU38800" /EC_number="3.-.-.-" /function="16.8: Protect" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 22277649; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative exported polysaccharide deacetylase, lipoprotein" /protein_id="NP_391759.1" /db_xref="EnsemblGenomes-Gn:BSU38800" /db_xref="EnsemblGenomes-Tr:CAB15906" /db_xref="GOA:P94361" /db_xref="InterPro:IPR002509" /db_xref="InterPro:IPR011330" /db_xref="SubtiList:BG12544" /db_xref="UniProtKB/Swiss-Prot:P94361" /translation="MKRLFLSIFLLGSCLALAACADQEANAEQPMPKAEQKKPEKKAV QVQKKEDDTSAWIKTEKPAKLPILMYHSISSGNSLRVPKKEFEAHMKWLHDNGYQTLT PKEASLMLTQDKKPSEKCVLITFDDGYTDNYQDAYPVLKKYGMKATIFMIGKSIGHKH HLTEEQMKEMAQHGISIESHTIDHLELNGLTPQQQQSEMADSKKLFDNMFHQQTTIIS YPVGRYNEETLKAAEKTGYQMGVTTEPGAASRDQGMYALHRVRVSPGMSGSAFGAYIE SMK*" gene complement(3848785..3849624) /gene="yxkH" /locus_tag="BSU_38800" /old_locus_tag="BSU38800" promotor_-10 complement(3849650..3849668) /Source="Nicolas_upshift_promotors" /id="U3056" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2813 /SigmaFactorBS="tcaaaaaaaccggacatggagacatgtccggttttttgctAT TGAAAAtctcagaatcaaACCGATGAAAAAGGAGGAAgaaatagacagaaagcaggag a" /listShort="yxkH, S1488" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3849668) /Source="Nicolas_upshifts" /id="U3056" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2813 /SigmaFactorBS="tcaaaaaaaccggacatggagacatgtccggttttttgctAT TGAAAAtctcagaatcaaACCGATGAAAAAGGAGGAAgaaatagacagaaagcaggag a" /listShort="yxkH, S1488" /GFF_Attribute="listLong" promotor_-35 complement(3849681..3849688) /Source="Nicolas_upshift_promotors" /id="U3056" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2813 /SigmaFactorBS="tcaaaaaaaccggacatggagacatgtccggttttttgctAT TGAAAAtctcagaatcaaACCGATGAAAAAGGAGGAAgaaatagacagaaagcaggag a" /listShort="yxkH, S1488" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 3849683 /Source="Nicolas_upshifts" /id="D2010" /incds=0 /nref=27 /ntot=142 /MaxReadThrough="0.40982" /MaxDrop="6.50242" /score="33.6694147" /energy="-13.4" /TU="NA" /idTUdmin="U3055" /TUdmin=3 /isTUend="TRUE" CDS complement(3849731..3850828) /gene="msmX" /locus_tag="BSU_38810" /old_locus_tag="BSU38810" /EC_number="3.6.3.-" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:16707683" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16707683; Product type t: transporter" /codon_start=1 /transl_table=11 /product="multiple sugar (maltodextrins) transporter ATP-binding protein" /protein_id="NP_391760.1" /db_xref="EnsemblGenomes-Gn:BSU38810" /db_xref="EnsemblGenomes-Tr:CAB15907" /db_xref="GOA:P94360" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR005116" /db_xref="InterPro:IPR008995" /db_xref="InterPro:IPR017871" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG11954" /db_xref="UniProtKB/Swiss-Prot:P94360" /translation="MAELRMEHIYKFYDQKEPAVDDFNLHIADKEFIVFVGPSGCGKS TTLRMVAGLEEISKGDFYIEGKRVNDVAPKDRDIAMVFQNYALYPHMTVYDNIAFGLK LRKMPKPEIKKRVEEAAKILGLEEYLHRKPKALSGGQRQRVALGRAIVRDAKVFLMDE PLSNLDAKLRVQMRAEIIKLHQRLQTTTIYVTHDQTEALTMATRIVVMKDGKIQQIGT PKDVYEFPENVFVGGFIGSPAMNFFKGKLTDGLIKIGSAALTVPEGKMKVLREKGYIG KEVIFGIRPEDIHDELIVVESYKNSSIKAKINVAELLGSEIMIYSQIDNQDFIARIDA RLDIQSGDELTVAFDMNKGHFFDSETEVRIR*" gene complement(3849731..3850828) /gene="msmX" /locus_tag="BSU_38810" /old_locus_tag="BSU38810" downshifts complement(3849732) /Source="Nicolas_upshifts" /id="D2011" /incds=0 /nref=81 /ntot=171 /MaxReadThrough="3.31232" /MaxDrop="7.04855" /score="29.2689404" /energy="-14.4" /TU="U3057" /idTUdmin="U3058" /TUdmin=2 /isTUend="TRUE" promotor_-10 complement(3850861..3850880) /Source="Nicolas_upshift_promotors" /id="U3057" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.549450549450549" /psig="0.998001998001998" /xcortree=355 /SigmaFactorBS="tgcacgaaaaatggctgggtgattttatgaacgctgccCATT TTAGcgagagggaattGCTGTTACACTCAATATAAGaaagcgtttacaataacaaagg g" /listShort="msmX" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3850878) /Source="Nicolas_upshifts" /id="U3057" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.549450549450549" /psig="0.998001998001998" /xcortree=355 /SigmaFactorBS="tgcacgaaaaatggctgggtgattttatgaacgctgccCATT TTAGcgagagggaattGCTGTTACACTCAATATAAGaaagcgtttacaataacaaagg g" /listShort="msmX" /GFF_Attribute="listLong" S_feature complement(3850880..3850948) /Source="Nicolas_S_feature" /locus_tag="new_3985282_3985350_c" /HighExp="M0t90, M40t90, Lbstat, Lbtran, T2.0H, dia5, T2.30H, M9-stat, S2, T3.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1490" promotor_-35 complement(3850893..3850900) /Source="Nicolas_upshift_promotors" /id="U3057" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.549450549450549" /psig="0.998001998001998" /xcortree=355 /SigmaFactorBS="tgcacgaaaaatggctgggtgattttatgaacgctgccCATT TTAGcgagagggaattGCTGTTACACTCAATATAAGaaagcgtttacaataacaaagg g" /listShort="msmX" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3850949..3851842) /gene="yxkF" /locus_tag="BSU_38820" /old_locus_tag="BSU38820" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:10746760" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10746760; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator (regulates yxkF-msmX expression)" /protein_id="NP_391761.1" /db_xref="EnsemblGenomes-Gn:BSU38820" /db_xref="EnsemblGenomes-Tr:CAB15908" /db_xref="InterPro:IPR025736" /db_xref="SubtiList:BG12543" /db_xref="UniProtKB/Swiss-Prot:P94359" /translation="MKSLLAIYPGSIVSEELCIREGCLCFFDESNQRYISIPKTEISE KEVLVLQSFLTPADEGNQLSMKSPEENKWFSFLFSRGELPAYIKKRTRFVHFHLFGKI ERTSFTEAVRHFWPVSFVIVWIHEDRGVIVEQESEAAAEKDELESLAKVLESDFYFSV RFYAGRFYEPDECLRKHYAREQAYFLFAEKRLPQVQSVTFEMIFPFLLLETEKEKLET LLSEEAELLFGSESELRKTIKLFIENNSNVTLTAKKLHLHRNSLQYRIDKFIERSGID IKSYKGALLAYFICLQNESSE*" gene complement(3850949..3851842) /gene="yxkF" /locus_tag="BSU_38820" /old_locus_tag="BSU38820" promotor_-10 complement(3851869..3851888) /Source="Nicolas_upshift_promotors" /id="U3058" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.949050949050949" /psig=1 /xcortree=3179 /SigmaFactorBS="ttcagtttctcgtctatctataccggatatactctttttTAG TGGAGaacatgtgtgtttCGCCTTATACTGAATATACAgatccttacataagagagga g" /listShort="yxkF, S1490, msmX" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3851888) /Source="Nicolas_upshifts" /id="U3058" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.949050949050949" /psig=1 /xcortree=3179 /SigmaFactorBS="ttcagtttctcgtctatctataccggatatactctttttTAG TGGAGaacatgtgtgtttCGCCTTATACTGAATATACAgatccttacataagagagga g" /listShort="yxkF, S1490, msmX" /GFF_Attribute="listLong" promotor_-35 complement(3851902..3851909) /Source="Nicolas_upshift_promotors" /id="U3058" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.949050949050949" /psig=1 /xcortree=3179 /SigmaFactorBS="ttcagtttctcgtctatctataccggatatactctttttTAG TGGAGaacatgtgtgtttCGCCTTATACTGAATATACAgatccttacataagagagga g" /listShort="yxkF, S1490, msmX" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 3851916..3851921 /Source="Nicolas_upshift_promotors" /id="U3059" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.93006993006993" /psig="0.93006993006993" /xcortree=1025 /SigmaFactorBS="gcgaaacacacatgttctccactaaaaaagAGTATAtccggt atagatagaCGAGAAACTGAAAGGGAAAcctcattcgtttacatattggcttcagcgg a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3851937..3851955 /Source="Nicolas_upshift_promotors" /id="U3059" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.93006993006993" /psig="0.93006993006993" /xcortree=1025 /SigmaFactorBS="gcgaaacacacatgttctccactaaaaaagAGTATAtccggt atagatagaCGAGAAACTGAAAGGGAAAcctcattcgtttacatattggcttcagcgg a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3851946 /Source="Nicolas_upshifts" /id="U3059" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.93006993006993" /psig="0.93006993006993" /xcortree=1025 /SigmaFactorBS="gcgaaacacacatgttctccactaaaaaagAGTATAtccggt atagatagaCGAGAAACTGAAAGGGAAAcctcattcgtttacatattggcttcagcgg a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 3851963..3851969 /Source="Nicolas_upshift_promotors" /id="U3060" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=249 /SigmaFactorBS="agatagacgagaaactgaaagggaaacctcattCGTTTACat attggcttcagcGGAAATAGAAGAAGACATGcaggaccaaaggagggtcatcttatga g" /listShort="aldY" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3851984..3852002 /Source="Nicolas_upshift_promotors" /id="U3060" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=249 /SigmaFactorBS="agatagacgagaaactgaaagggaaacctcattCGTTTACat attggcttcagcGGAAATAGAAGAAGACATGcaggaccaaaggagggtcatcttatga g" /listShort="aldY" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3851990 /Source="Nicolas_upshifts" /id="U3060" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=249 /SigmaFactorBS="agatagacgagaaactgaaagggaaacctcattCGTTTACat attggcttcagcGGAAATAGAAGAAGACATGcaggaccaaaggagggtcatcttatga g" /listShort="aldY" /GFF_Attribute="listLong" CDS 3852026..3853483 /gene="aldY" /locus_tag="BSU_38830" /old_locus_tag="BSU38830" /EC_number="1.2.1.-" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 10482513; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative aldehyde dehydrogenase" /protein_id="NP_391762.1" /db_xref="EnsemblGenomes-Gn:BSU38830" /db_xref="EnsemblGenomes-Tr:CAB15909" /db_xref="GOA:P94358" /db_xref="InterPro:IPR015590" /db_xref="InterPro:IPR016161" /db_xref="InterPro:IPR016162" /db_xref="InterPro:IPR029510" /db_xref="PDB:4DNG" /db_xref="SubtiList:BG11903" /db_xref="UniProtKB/Swiss-Prot:P94358" /translation="MSFETLNKSFINGKWTGGESGRTEDILNPYDQSVITTASLATGK QLEDAFDIAQKAQKEWAKSTTEDRKAVLQKARGYLHENRDDIIMMIARETGGTIIKST IELEQTIAILDEAMTYTGELGGVKEVPSDIEGKTNKIYRLPLGVISSISPFNFPMNLS MRSIAPAIALGNSVVHKPDIQTAISGGTIIAKAFEHAGLPAGVLNVMLTDVKEIGDGM LTNPIPRLISFTGSTAVGRHIGEIAGRAFKRMALELGGNNPFAVLSDADVDRAVDAAI FGKFIHQGQICMIINRIIVHQDVYDEFVEKFTARVKQLPYGDQTDPKTVVGPLINERQ IEKALEIIEQAKTDGIELAVEGKRVGNVLTPYVFVGADNNSKIAQTELFAPIATIIKA GSDQEAIDMANDTEYGLSSAVFTSDLEKGEKFALQIDSGMTHVNDQSVNDSPNIAFGG NKASGVGRFGNPWVVEEFTVTKWISIQKQYRKYPF*" gene 3852026..3853483 /gene="aldY" /locus_tag="BSU_38830" /old_locus_tag="BSU38830" promotor_-10 complement(3852909..3852927) /Source="Nicolas_upshift_promotors" /id="U3061" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.894105894105894" /psig="0.894105894105894" /xcortree=1207 /SigmaFactorBS="gtttgatcgccgtacggaagctgtttgacacgggcggTGAAT TtttctacaaactcaTCGTATACATCTTGATGAAcgatgatcctgttgataatcatac a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3852924) /Source="Nicolas_upshifts" /id="U3061" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.894105894105894" /psig="0.894105894105894" /xcortree=1207 /SigmaFactorBS="gtttgatcgccgtacggaagctgtttgacacgggcggTGAAT TtttctacaaactcaTCGTATACATCTTGATGAAcgatgatcctgttgataatcatac a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(3852942..3852947) /Source="Nicolas_upshift_promotors" /id="U3061" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.894105894105894" /psig="0.894105894105894" /xcortree=1207 /SigmaFactorBS="gtttgatcgccgtacggaagctgtttgacacgggcggTGAAT TtttctacaaactcaTCGTATACATCTTGATGAAcgatgatcctgttgataatcatac a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 3853464 /Source="Nicolas_upshifts" /id="D2012" /incds=0 /nref=14 /ntot=39 /MaxReadThrough="1.43471" /MaxDrop="4.03346" /score="25.9343422" /energy="-13.8" /TU="NA" /idTUdmin="U3060" /TUdmin=0 /isTUend="TRUE" downshifts 3853508 /Source="Nicolas_upshifts" /id="D2013" /incds=0 /nref=1 /ntot=1 /MaxReadThrough="1.40793" /MaxDrop="3.07407" /score="25.9343422" /energy="-13.8" /TU="NA" /idTUdmin="U3060" /TUdmin=44 /isTUend="FALSE" CDS complement(3853525..3854361) /gene="gdnE" /locus_tag="BSU_38840" /old_locus_tag="BSU38840" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 10735877, 10931887, 15096624, 15849754, 16850406, 21317561; Product type t : transporter" /codon_start=1 /transl_table=11 /product="guanidinium exporter" /protein_id="NP_391763.1" /db_xref="EnsemblGenomes-Gn:BSU38840" /db_xref="EnsemblGenomes-Tr:CAB15910" /db_xref="GOA:P94357" /db_xref="InterPro:IPR003740" /db_xref="InterPro:IPR019264" /db_xref="SubtiList:BG12542" /db_xref="UniProtKB/Swiss-Prot:P94357" /translation="MKKRMLDVLMLVIGAFFFALAVNLFAIPNDLGEGGVTGITLILY YLFQWSPGVTNFILNAFLLLIGYKFLDGKTTVYTIIAVAANSLFLHLTHGWSIPSDEL IINTIFAGVFAGVGIGMIIRVGGTTAGSAILARIANKYLDWNISYALLFFDLIVVFSS YFIIGAEKMMFTIVMLYIGTKVMDFIIEGLNTKKAITVISENKSEIAEQVNTLMDRGV TILSGKGNYTGQSKEILYIVINKQELSMLKKIIRSCDKKAFVIVHDVRDVFGEGFVDI SK*" gene complement(3853525..3854361) /gene="gdnE" /locus_tag="BSU_38840" /old_locus_tag="BSU38840" downshifts complement(3853543) /Source="Nicolas_upshifts" /id="D2014" /incds=0 /nref=19 /ntot=137 /MaxReadThrough="1.00689" /MaxDrop="4.07213" /score="21.5028874" /energy="-13.8" /TU="NA" /idTUdmin="U3062" /TUdmin="-3" /isTUend="TRUE" misc_RNA complement(3854438..3854540) /gene="gdwB" /locus_tag="BSU_misc_RNA_60" /product="guanidine riboswitch (type I)" /experiment="publication(s) with functional evidences, PMID:21317561, 27989440, 28096518" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 21317561, 27989440, 28096518" gene complement(3854438..3854540) /gene="gdwB" /locus_tag="BSU_misc_RNA_60" downshifts complement(3854464) /Source="Nicolas_upshifts" /id="D2015" /incds=0 /nref=194 /ntot=247 /MaxReadThrough="3.21415" /MaxDrop="5.58394" /score="-0.190335837" /energy="-10.7" /TU="U3062" /idTUdmin="U3065" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(3854566..3854585) /Source="Nicolas_upshift_promotors" /id="U3062" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.483516483516484" /psig="0.999000999001" /xcortree=2404 /SigmaFactorBS="ccagcttatctgatgaaaactccgcaaataccCCTTGAAcca attcgaaccgTCCCTTATAATGCTAATATTggaaagtgaaaaggatatgataaaaaca g" /listShort="NA, yxkD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3854577) /Source="Nicolas_upshifts" /id="U3062" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.483516483516484" /psig="0.999000999001" /xcortree=2404 /SigmaFactorBS="ccagcttatctgatgaaaactccgcaaataccCCTTGAAcca attcgaaccgTCCCTTATAATGCTAATATTggaaagtgaaaaggatatgataaaaaca g" /listShort="NA, yxkD" /GFF_Attribute="listLong" S_feature complement(3854579..3855320) /Source="Nicolas_S_feature" /locus_tag="new_3988981_3989722_c" /HighExp="S6, S8, S7, C30, S5, Gly, C90, Fru, BT, Pyr" /AntisenseName="yxkC" /AntisenseCor="-0.38162570069976298" /AntisenseRegPval="-10" /CDS_PredictionProba="NA" /TUshortSig="SigK" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1491" promotor_-35 complement(3854599..3854605) /Source="Nicolas_upshift_promotors" /id="U3062" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.483516483516484" /psig="0.999000999001" /xcortree=2404 /SigmaFactorBS="ccagcttatctgatgaaaactccgcaaataccCCTTGAAcca attcgaaccgTCCCTTATAATGCTAATATTggaaagtgaaaaggatatgataaaaaca g" /listShort="NA, yxkD" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 3854657..3854664 /Source="Nicolas_upshift_promotors" /id="U3063" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2814 /SigmaFactorBS="cagataagctggaaaaaaatacgatttatctATTAAAAAaga acagatataACCGATAAGAAAAAAAGCAtatattttacaagcgaatgtaactataaat g" /listShort="S1492, yxkC, S1493" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3854677..3854695 /Source="Nicolas_upshift_promotors" /id="U3063" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2814 /SigmaFactorBS="cagataagctggaaaaaaatacgatttatctATTAAAAAaga acagatataACCGATAAGAAAAAAAGCAtatattttacaagcgaatgtaactataaat g" /listShort="S1492, yxkC, S1493" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3854686 /Source="Nicolas_upshifts" /id="U3063" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2814 /SigmaFactorBS="cagataagctggaaaaaaatacgatttatctATTAAAAAaga acagatataACCGATAAGAAAAAAAGCAtatattttacaagcgaatgtaactataaat g" /listShort="S1492, yxkC, S1493" /GFF_Attribute="listLong" S_feature 3854696..3854781 /Source="Nicolas_S_feature" /locus_tag="new_3989098_3989183" /HighExp="Cold, SMM, MG 150, GM 90, Glu, C30, GM 150, GM-0.2, GM 15, Fru" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigD" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1492" promotor_-35 3854757..3854764 /Source="Nicolas_upshift_promotors" /id="U3064" /multdbtbs="SigD" /comp="M17" /sig="SigA" /pcomp="0.731268731268731" /psig=1 /xcortree=2816 /SigmaFactorBS="aatgataataattataagaaattcataattttatATTGACTA agagaaataatatAGGCATTATAGTACATATGTttcgtacattttattacataggagg a" /listShort="yxkC, S1493" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3854778..3854797 /Source="Nicolas_upshift_promotors" /id="U3064" /multdbtbs="SigD" /comp="M17" /sig="SigA" /pcomp="0.731268731268731" /psig=1 /xcortree=2816 /SigmaFactorBS="aatgataataattataagaaattcataattttatATTGACTA agagaaataatatAGGCATTATAGTACATATGTttcgtacattttattacataggagg a" /listShort="yxkC, S1493" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3854783 /Source="Nicolas_upshifts" /id="U3064" /multdbtbs="SigD" /comp="M17" /sig="SigA" /pcomp="0.731268731268731" /psig=1 /xcortree=2816 /SigmaFactorBS="aatgataataattataagaaattcataattttatATTGACTA agagaaataatatAGGCATTATAGTACATATGTttcgtacattttattacataggagg a" /listShort="yxkC, S1493" /GFF_Attribute="listLong" CDS 3854929..3855471 /gene="yxkC" /locus_tag="BSU_38850" /old_locus_tag="BSU38850" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 12823818, 15033535" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_391764.2" /db_xref="EnsemblGenomes-Gn:BSU38850" /db_xref="EnsemblGenomes-Tr:CAB15911" /db_xref="GOA:P94356" /db_xref="InterPro:IPR029050" /db_xref="InterPro:IPR029051" /db_xref="SubtiList:BG12541" /db_xref="UniProtKB/Swiss-Prot:P94356" /translation="MRHKIITFILAVVVIIIIGNMIGGGGGSEATSKTSSSSKAETEK TYNIGDTVKTEKTEVTVTKVEDRDTVGTQYVEKKASEGGTIVAVQYTIKNVSKKPISS FSIPTVKLVDADGTSYDSDIDASVNYATETKVDNSKILSDLNPNIKVTGVKAFEVDKE AYAKGTWKLKFSNDVIVKIK*" gene 3854929..3855471 /gene="yxkC" /locus_tag="BSU_38850" /old_locus_tag="BSU38850" promotor_-10 complement(3855296..3855315) /Source="Nicolas_upshift_promotors" /id="U3065" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1368 /SigmaFactorBS="cctgttactttaatattaggatttagatcactcaaaatttta GAGTTATCAActtttgtctcagtTGCATAGTTTACAGAAGCATcaatatcagaatcat a" /listShort="S1491, NA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3855320) /Source="Nicolas_upshifts" /id="U3065" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1368 /SigmaFactorBS="cctgttactttaatattaggatttagatcactcaaaatttta GAGTTATCAActtttgtctcagtTGCATAGTTTACAGAAGCATcaatatcagaatcat a" /listShort="S1491, NA" /GFF_Attribute="listLong" promotor_-35 complement(3855329..3855338) /Source="Nicolas_upshift_promotors" /id="U3065" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1368 /SigmaFactorBS="cctgttactttaatattaggatttagatcactcaaaatttta GAGTTATCAActtttgtctcagtTGCATAGTTTACAGAAGCATcaatatcagaatcat a" /listShort="S1491, NA" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 3855461 /Source="Nicolas_upshifts" /id="D2016" /incds=0 /nref=78 /ntot=276 /MaxReadThrough="4.33141" /MaxDrop="6.78221" /score="9.28209494" /energy="-14.4" /TU="U3063,U3064" /idTUdmin="U3064" /TUdmin="-181" /isTUend="FALSE" S_feature 3855506..3855828 /Source="Nicolas_S_feature" /locus_tag="new_3989908_3990230" /HighExp="Cold, C30, Heat, Fru, Glu, C90, BMM, Glucon, M/G, Mal" /AntisenseName="galE" /AntisenseCor="0.165797390333391" /AntisenseRegPval="-2.2000000000000002" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigD" /TUshortPSig="1, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S1493" CDS complement(3855546..3856565) /gene="galE" /locus_tag="BSU_38860" /old_locus_tag="BSU38860" /EC_number="5.1.3.7" /EC_number="5.1.3.2" /function="16.11: Scavenge (Catabolism)" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:1906927, 9555917, 14597172" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1906927, 9555917, 14597172; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="UDP-glucose 4-epimerase" /protein_id="NP_391765.1" /db_xref="EnsemblGenomes-Gn:BSU38860" /db_xref="EnsemblGenomes-Tr:CAB15912" /db_xref="GOA:P55180" /db_xref="InterPro:IPR005886" /db_xref="InterPro:IPR008089" /db_xref="InterPro:IPR016040" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG11837" /db_xref="UniProtKB/Swiss-Prot:P55180" /translation="MAILVTGGAGYIGSHTCVELLNSGYEIVVLDNLSNSSAEALNRV KEITGKDLTFYEADLLDREAVDSVFAENEIEAVIHFAGLKAVGESVAIPLKYYHNNLT GTFILCEAMEKYGVKKIVFSSSATVYGVPETSPITEDFPLGATNPYGQTKLMLEQILR DLHTADNEWSVALLRYFNPFGAHPSGRIGEDPNGIPNNLMPYVAQVAVGKLEQLSVFG NDYPTKDGTGVRDYIHVVDLAEGHVKALEKVLNSTGADAYNLGTGTGYSVLEMVKAFE KVSGKEVPYRFADRRPGDIATCFADPAKAKRELGWEAKRGLEEMCADSWRWQSSNVNG YKSAE*" gene complement(3855546..3856565) /gene="galE" /locus_tag="BSU_38860" /old_locus_tag="BSU38860" downshifts complement(3855564) /Source="Nicolas_upshifts" /id="D2017" /incds=0 /nref=235 /ntot=261 /MaxReadThrough="1.7919" /MaxDrop="7.32805" /score="24.6899971" /energy="-14.8" /TU="NA" /idTUdmin="U3066" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(3856591..3856610) /Source="Nicolas_upshift_promotors" /id="U3066" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.794205794205794" /psig="0.988011988011988" /xcortree=2154 /SigmaFactorBS="aaaaactattaataaacgattaaacttcttaaaaatgGATGt ggaccggttctaaACACTATATAATGAAAACAGgtcattttttaggagggtttacatc a" /listShort="galE" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3856605) /Source="Nicolas_upshifts" /id="U3066" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.794205794205794" /psig="0.988011988011988" /xcortree=2154 /SigmaFactorBS="aaaaactattaataaacgattaaacttcttaaaaatgGATGt ggaccggttctaaACACTATATAATGAAAACAGgtcattttttaggagggtttacatc a" /listShort="galE" /GFF_Attribute="listLong" promotor_-35 complement(3856625..3856628) /Source="Nicolas_upshift_promotors" /id="U3066" /multdbtbs="SigA" /comp="M7" /sig="SigA" /pcomp="0.794205794205794" /psig="0.988011988011988" /xcortree=2154 /SigmaFactorBS="aaaaactattaataaacgattaaacttcttaaaaatgGATGt ggaccggttctaaACACTATATAATGAAAACAGgtcattttttaggagggtttacatc a" /listShort="galE" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3856680..3857186) /gene="yxkA" /locus_tag="BSU_38870" /old_locus_tag="BSU38870" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type f: factor" /codon_start=1 /transl_table=11 /product="putative phospholipid binding protein" /protein_id="NP_391766.1" /db_xref="EnsemblGenomes-Gn:BSU38870" /db_xref="EnsemblGenomes-Tr:CAB15913" /db_xref="InterPro:IPR005247" /db_xref="InterPro:IPR008914" /db_xref="InterPro:IPR036610" /db_xref="SubtiList:BG11899" /db_xref="UniProtKB/Swiss-Prot:P55185" /translation="MNIYVEANPYLHDKYSKYADEKYKREGNPFVSFPIHFDDIPSGA KTLALTFIDHDAIPVCGFSWIHWTAANIPAYIGELPEHASEERQDLMIQGQNSFASPL AGSNDPKVIHQYCGPTPPDKDHAYTLTVYALDAELNLQPGFYLNELYQEMKEHILAET SIELLARV*" gene complement(3856680..3857186) /gene="yxkA" /locus_tag="BSU_38870" /old_locus_tag="BSU38870" promotor_-10 complement(3857192..3857211) /Source="Nicolas_upshift_promotors" /id="U3067" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.971028971028971" /psig="0.971028971028971" /xcortree=98 /SigmaFactorBS="acgtttacatgcgtatttgtttatcactgattatacatcgat tCGTTTAGtatacctatagaaCGAGAAAATAGAGAGAGGGAttcatatgaacatatac g" /listShort="yxkA, galE" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3857214) /Source="Nicolas_upshifts" /id="U3067" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.971028971028971" /psig="0.971028971028971" /xcortree=98 /SigmaFactorBS="acgtttacatgcgtatttgtttatcactgattatacatcgat tCGTTTAGtatacctatagaaCGAGAAAATAGAGAGAGGGAttcatatgaacatatac g" /listShort="yxkA, galE" /GFF_Attribute="listLong" promotor_-35 3857216..3857219 /Source="Nicolas_upshift_promotors" /id="U3068" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.854145854145854" /psig="0.998001998001998" /xcortree=1872 /SigmaFactorBS="atatgttcatatgaatccctctctctattttctcgttctATA GgtatactaaacgaaTCGATGTATAATCAGTGATAaacaaatacgcatgtaaacgtaa c" /listShort="yxjO" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 complement(3857225..3857231) /Source="Nicolas_upshift_promotors" /id="U3067" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.971028971028971" /psig="0.971028971028971" /xcortree=98 /SigmaFactorBS="acgtttacatgcgtatttgtttatcactgattatacatcgat tCGTTTAGtatacctatagaaCGAGAAAATAGAGAGAGGGAttcatatgaacatatac g" /listShort="yxkA, galE" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3857234..3857253 /Source="Nicolas_upshift_promotors" /id="U3068" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.854145854145854" /psig="0.998001998001998" /xcortree=1872 /SigmaFactorBS="atatgttcatatgaatccctctctctattttctcgttctATA GgtatactaaacgaaTCGATGTATAATCAGTGATAaacaaatacgcatgtaaacgtaa c" /listShort="yxjO" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3857237 /Source="Nicolas_upshifts" /id="U3068" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.854145854145854" /psig="0.998001998001998" /xcortree=1872 /SigmaFactorBS="atatgttcatatgaatccctctctctattttctcgttctATA GgtatactaaacgaaTCGATGTATAATCAGTGATAaacaaatacgcatgtaaacgtaa c" /listShort="yxjO" /GFF_Attribute="listLong" CDS 3857316..3858191 /gene="yxjO" /locus_tag="BSU_38880" /old_locus_tag="BSU38880" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 12169591; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative transcriptional regulator (LysR family)" /protein_id="NP_391767.1" /db_xref="EnsemblGenomes-Gn:BSU38880" /db_xref="EnsemblGenomes-Tr:CAB15914" /db_xref="GOA:P55181" /db_xref="InterPro:IPR000847" /db_xref="InterPro:IPR005119" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG11898" /db_xref="UniProtKB/Swiss-Prot:P55181" /translation="MDLKWLQTFIAAAESESFREAAEHLYLTQPAVSQHMRKLEDELD MRLFLHSGRRVVLTDEGRLFLPYAKEMIHVYQAGKQKVSQWKQGYSRSLTLAVHPYIA SYILPRFLPAYIQKHPHVELSTHVAGSDAIKQAVEHNEADIGLSRKDPNTNTLYYQHI CEGTLCLAAPFQESRPDAASVLTRYRLLTHDHPSYGDAFLDNIRSHYPYLQMMAVGQT DTAVHMMKAGMGASFLPTYIIKQEEAEKKLMAVSTPAHLELPASQTFMMWKRNSEDIQ HFHAMLHDFMQREQV*" gene 3857316..3858191 /gene="yxjO" /locus_tag="BSU_38880" /old_locus_tag="BSU38880" S_feature complement(3857566..3857654) /Source="Nicolas_S_feature" /locus_tag="new_3991968_3992056_c" /HighExp="GM 60, MG-0.1, MG 10, GM 5, S8, T0.30H, BC, S6, GM 15, GM 150" /AntisenseName="yxjO" /AntisenseCor="0.14032494397598999" /AntisenseRegPval="-1.7" /CDS_PredictionProba="NA" /TUshortSig="Sig-" /TUshortPSig="0.0669" /TUlongSig="NA" /TUlongPSig="NA" /label="S1494" downshifts complement(3857588) /Source="Nicolas_upshifts" /id="D2018" /incds=1 /nref=22 /ntot=45 /MaxReadThrough="0.10815" /MaxDrop="6.05884" /score="5.06408541" /energy="-5.6" /TU="NA" /idTUdmin="U3069" /TUdmin=0 /isTUend="TRUE" promotor_no_box complement(3857614..3857714) /Source="Nicolas_upshift_promotors" /id="U3069" /multdbtbs="-" /comp="M21" /sig="Sig-" /pcomp="0.507492507492508" /psig="0.066933066933067" /xcortree=1478 /SigmaFactorBS="tttaatagcgtcagatccagccacatgagttgaaagctcgac atgcggatgtttttggatataggctggcagaaagcgaggcaagatataggacgcaatg t" /listShort="S1494" /GFF_Attribute="listLong" /label="promotor_no_box" upshifts complement(3857654) /Source="Nicolas_upshifts" /id="U3069" /multdbtbs="-" /comp="M21" /sig="Sig-" /pcomp="0.507492507492508" /psig="0.066933066933067" /xcortree=1478 /SigmaFactorBS="tttaatagcgtcagatccagccacatgagttgaaagctcgac atgcggatgtttttggatataggctggcagaaagcgaggcaagatataggacgcaatg t" /listShort="S1494" /GFF_Attribute="listLong" CDS 3858269..3858742 /gene="yxjN" /locus_tag="BSU_38890" /old_locus_tag="BSU38890" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative integral inner membrane protein of unknown function" /protein_id="NP_391768.1" /db_xref="EnsemblGenomes-Gn:BSU38890" /db_xref="EnsemblGenomes-Tr:CAB15915" /db_xref="GOA:P55182" /db_xref="InterPro:IPR009916" /db_xref="InterPro:IPR020223" /db_xref="SubtiList:BG11897" /db_xref="UniProtKB/Swiss-Prot:P55182" /translation="MAMSPYIFIVLILIILSMYRERTVKPGKLLIIPLLLLWGVSASF QPAYFHSVLHVAISGILLLIGLACGFGIGKMVNVRIHPETGKVTSRGSLGSVILILVI LSLRMAARTWLPESNEMFIAIIHSMFFVPLGTITARNIMLYKAYRRLTAGKVSIQ*" gene 3858269..3858742 /gene="yxjN" /locus_tag="BSU_38890" /old_locus_tag="BSU38890" CDS 3858760..3859980 /gene="yxjM" /locus_tag="BSU_38900" /old_locus_tag="BSU38900" /function="16.3: Control" /function="16.12: Sense" /experiment="publication(s) with functional evidences, PMID:11717295" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11717295; Product type rc: receptor" /codon_start=1 /transl_table=11 /product="two-component sensor histidine kinase [YxjL]" /protein_id="NP_391769.1" /db_xref="EnsemblGenomes-Gn:BSU38900" /db_xref="EnsemblGenomes-Tr:CAB15916" /db_xref="GOA:P55183" /db_xref="InterPro:IPR003594" /db_xref="InterPro:IPR011712" /db_xref="InterPro:IPR036890" /db_xref="SubtiList:BG11896" /db_xref="UniProtKB/Swiss-Prot:P55183" /translation="MNGQTPARHYYKKLVPSLILILNCIQFLSHPTKADPILLAFVFA VYLAFIWIIPYVASTAVSLSIFIGLWLLTDFFWAVSGQEQGAAYFLIVFLMIYAAFRL PSRLSLIFTACLIGGNILLLSSQGGSLNTIISNISIMLGLYVLFSSMRFRREARREAE RNHAELAKMHVQLEHAHKELQKAHAELQEASVLSLRYAVLEERTRIARDIHDSIGHEL TSVIVQLQSLPYILKSSKEDSEKVIQNVLSVARECLQEVRSVVHQMGRSESMVGLTAL RGLIHQVEERSGLHVSLDTAGLSEESWPPNVSETIYRILQEALTNIIRHADASHAAAV ISNDKSHLYVTITDDGQFTGSLTYGFGLTGMKERAEKAGGSLTFSAVQPSGLKIELSL PLMTTNKEQKDEQR*" gene 3858760..3859980 /gene="yxjM" /locus_tag="BSU_38900" /old_locus_tag="BSU38900" CDS 3859967..3860623 /gene="yxjL" /locus_tag="BSU_38910" /old_locus_tag="BSU38910" /function="16.12: Sense" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:11717295" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11717295; Product type r: regulator" /codon_start=1 /transl_table=11 /product="two-component response regulator [YxjM]" /protein_id="NP_391770.1" /db_xref="EnsemblGenomes-Gn:BSU38910" /db_xref="EnsemblGenomes-Tr:CAB15917" /db_xref="GOA:P55184" /db_xref="InterPro:IPR000792" /db_xref="InterPro:IPR001789" /db_xref="InterPro:IPR011006" /db_xref="InterPro:IPR016032" /db_xref="InterPro:IPR036388" /db_xref="SubtiList:BG11895" /db_xref="UniProtKB/Swiss-Prot:P55184" /translation="MNKDKIRVALADDQPLVREGFRYVINAQTDMTVSGEAGDGHDII ALAKQTKPDVILMDVQMPRCSGIEAAKDIMSALPNTKIVILTTFDTEEYVFEGIRAGA VGYLLKDTLPEELIDAIRAAARGEAIFRTVTAAKIISETFRAKQQTHAEELAEPFTKR ELEVLQQMAYGLRNEDIAEKLFVSESTVKTHVHRILQKCNAQDRTQAVVFAIRNGIVQ *" gene 3859967..3860623 /gene="yxjL" /locus_tag="BSU_38910" /old_locus_tag="BSU38910" promotor_-35 3860621..3860626 /Source="Nicolas_upshift_promotors" /id="U3070" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.863136863136863" /psig="0.998001998001998" /xcortree=2234 /SigmaFactorBS="aggcagtcgtttttgccattcgaaacggtattgtgcaaTAGA AAtctctcatcccgcCATGCTAAAATAAGACAAAGgagatgattggaaatgaaagaag a" /listShort="pepT" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3860640..3860659 /Source="Nicolas_upshift_promotors" /id="U3070" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.863136863136863" /psig="0.998001998001998" /xcortree=2234 /SigmaFactorBS="aggcagtcgtttttgccattcgaaacggtattgtgcaaTAGA AAtctctcatcccgcCATGCTAAAATAAGACAAAGgagatgattggaaatgaaagaag a" /listShort="pepT" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3860643 /Source="Nicolas_upshifts" /id="U3070" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.863136863136863" /psig="0.998001998001998" /xcortree=2234 /SigmaFactorBS="aggcagtcgtttttgccattcgaaacggtattgtgcaaTAGA AAtctctcatcccgcCATGCTAAAATAAGACAAAGgagatgattggaaatgaaagaag a" /listShort="pepT" /GFF_Attribute="listLong" CDS 3860673..3861905 /gene="pepT" /locus_tag="BSU_38920" /old_locus_tag="BSU38920" /EC_number="3.4.11.4" /function="16.6: Maintain" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:8978088, 10987140" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8978088, 10987140; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="peptidase T (tripeptidase)" /protein_id="NP_391771.1" /db_xref="EnsemblGenomes-Gn:BSU38920" /db_xref="EnsemblGenomes-Tr:CAB15918" /db_xref="GOA:P55179" /db_xref="InterPro:IPR001261" /db_xref="InterPro:IPR002933" /db_xref="InterPro:IPR010161" /db_xref="InterPro:IPR011650" /db_xref="InterPro:IPR036264" /db_xref="SubtiList:BG11842" /db_xref="UniProtKB/Swiss-Prot:P55179" /translation="MKEEIIERFTTYVKVDTQSDESVDTCPSTPGQLTLGNMLVDELK SIGMQDAAIDENGYVMATLPSNTEKDVPTIGFLAHVDTATDFTGKNVNPQIIESYDGK DIVLNEQLQVTLSPDQFPELSGYKGHTLITTDGTTLLGADNKAGIAEIMTAMDYLIKH PEIKHGTIRVAFTPDEEIGRGPHKFDVKRFNASFAYTVDGGPLGELEYESFNAAAAKI TIKGNNVHPGTAKGKMINSAKIAMKLNSLLPADEAPEYTEGYEGFYHLLSIQGDVEET KLHYIIRDFDKENFQNRKETMKRAVEELQNEYGQDRILLDMNDQYYNMREKIEPVIEI VNIAKQAMENLGIEPKISPIRGGTDGSQLSYMGLPTPNIFTGGENFHGKFEYISVDNM VKAVNVIVEIAKQFEAQA*" gene 3860673..3861905 /gene="pepT" /locus_tag="BSU_38920" /old_locus_tag="BSU38920" downshifts complement(3860690) /Source="Nicolas_upshifts" /id="D2019" /incds=0 /nref=4 /ntot=116 /MaxReadThrough="0.86167" /MaxDrop="3.19485" /score="-2.15704435" /energy="-9.1" /TU="NA" /idTUdmin="U3069" /TUdmin="-3102" /isTUend="FALSE" downshifts 3861890 /Source="Nicolas_upshifts" /id="D2020" /incds=0 /nref=203 /ntot=244 /MaxReadThrough="3.3949" /MaxDrop="6.35116" /score="27.2051031" /energy="-13.5" /TU="U3070" /idTUdmin="U3070" /TUdmin="-22" /isTUend="TRUE" promotor_-35 3861951..3861960 /Source="Nicolas_upshift_promotors" /id="U3071" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1693 /SigmaFactorBS="ccagtccaaaaaaggactggcttttttgtgtgaaaaTGAAAC ATTTtaaacacgtcctCCGTAAAACAAGTATCaacaaatgaggaggaaaaacaatgac a" /listShort="S1495, S1496, S1497" /listLong="yxjJ, yxjI, NA, yxjH, NA, S1499, yxjG" /label="promotor_-35" promotor_-10 3861973..3861988 /Source="Nicolas_upshift_promotors" /id="U3071" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1693 /SigmaFactorBS="ccagtccaaaaaaggactggcttttttgtgtgaaaaTGAAAC ATTTtaaacacgtcctCCGTAAAACAAGTATCaacaaatgaggaggaaaaacaatgac a" /listShort="S1495, S1496, S1497" /listLong="yxjJ, yxjI, NA, yxjH, NA, S1499, yxjG" /label="promotor_-10" S_feature 3861975..3862197 /Source="Nicolas_S_feature" /locus_tag="new_3996377_3996599" /HighExp="T-0.40H, T0.30H, T0.0H, T-1.40H, T1.0H, T-1.10H, T3.30H, T2.0H, T1.30H, T3.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.80396299999999998" /TUshortSig="SigWXY" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1495" upshifts 3861975 /Source="Nicolas_upshifts" /id="U3071" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1693 /SigmaFactorBS="ccagtccaaaaaaggactggcttttttgtgtgaaaaTGAAAC ATTTtaaacacgtcctCCGTAAAACAAGTATCaacaaatgaggaggaaaaacaatgac a" /listShort="S1495, S1496, S1497" /listLong="yxjJ, yxjI, NA, yxjH, NA, S1499, yxjG" downshifts 3862154 /Source="Nicolas_upshifts" /id="D2021" /incds=0 /nref=162 /ntot=247 /MaxReadThrough="4.83682" /MaxDrop="4.66302" /score="-1.57383757" /energy="-6.2" /TU="U3071" /idTUdmin="U3070" /TUdmin=242 /isTUend="FALSE" promotor_-35 3862208..3862214 /Source="Nicolas_upshift_promotors" /id="U3072" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=236 /SigmaFactorBS="attcacccgtaccgcccaaatgctccgtaatttgggtttttT GTGTTCaattccgcaaaataGGGTATAAACCAAACAAGCaagaaaacagcacccaaaa a" /listShort="S1496, S1497, yxjJ, yxjI, NA" /listLong="yxjH, NA, S1499, yxjG" /label="promotor_-35" S_feature 3862227..3862327 /Source="Nicolas_S_feature" /locus_tag="new_3996629_3996729" /HighExp="Etha, Gly, Sw, Salt, B60, T0.30H, LoTm, M9-stat, T1.0H, B36" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigB, SigWXY" /TUshortPSig="1, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S1496" upshifts 3862227 /Source="Nicolas_upshifts" /id="U3072" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=236 /SigmaFactorBS="attcacccgtaccgcccaaatgctccgtaatttgggtttttT GTGTTCaattccgcaaaataGGGTATAAACCAAACAAGCaagaaaacagcacccaaaa a" /listShort="S1496, S1497, yxjJ, yxjI, NA" /listLong="yxjH, NA, S1499, yxjG" promotor_-10 3862229..3862247 /Source="Nicolas_upshift_promotors" /id="U3072" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=236 /SigmaFactorBS="attcacccgtaccgcccaaatgctccgtaatttgggtttttT GTGTTCaattccgcaaaataGGGTATAAACCAAACAAGCaagaaaacagcacccaaaa a" /listShort="S1496, S1497, yxjJ, yxjI, NA" /listLong="yxjH, NA, S1499, yxjG" /label="promotor_-10" promotor_-35 3862306..3862313 /Source="Nicolas_upshift_promotors" /id="U3073" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2830 /SigmaFactorBS="aggtaattcgaattacgtaaacttaggttaaaagttaTATAA AGGaatttattttatcGTCGATAGTAACTATAGAAccaatcatcaacaagagcaaaca g" /listShort="S1497, yxjJ" /listLong="yxjI, NA, yxjH, NA, S1499, yxjG" /label="promotor_-35" promotor_-10 3862327..3862345 /Source="Nicolas_upshift_promotors" /id="U3073" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2830 /SigmaFactorBS="aggtaattcgaattacgtaaacttaggttaaaagttaTATAA AGGaatttattttatcGTCGATAGTAACTATAGAAccaatcatcaacaagagcaaaca g" /listShort="S1497, yxjJ" /listLong="yxjI, NA, yxjH, NA, S1499, yxjG" /label="promotor_-10" S_feature 3862329..3862426 /Source="Nicolas_S_feature" /locus_tag="new_3996731_3996828" /HighExp="Etha, T0.30H, Gly, T1.0H, Sw, Salt, T1.30H, GM 15, B60, GM-0.1" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigD, SigB, SigWXY" /TUshortPSig="1, 1, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S1497" upshifts 3862329 /Source="Nicolas_upshifts" /id="U3073" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2830 /SigmaFactorBS="aggtaattcgaattacgtaaacttaggttaaaagttaTATAA AGGaatttattttatcGTCGATAGTAACTATAGAAccaatcatcaacaagagcaaaca g" /listShort="S1497, yxjJ" /listLong="yxjI, NA, yxjH, NA, S1499, yxjG" CDS 3862427..3862690 /gene="yxjJ" /locus_tag="BSU_38930" /old_locus_tag="BSU38930" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_391772.1" /db_xref="EnsemblGenomes-Gn:BSU38930" /db_xref="EnsemblGenomes-Tr:CAB15919" /db_xref="GOA:P94353" /db_xref="SubtiList:BG12540" /db_xref="UniProtKB/Swiss-Prot:P94353" /translation="MLFIDLEFFEYFLAFYPYNREYQNFFWEVCNMILFIIIALCGYL LFSFSKDNRRKPQKTSPLPAAAPHHNNLIDLDAIRQKRRMHLS*" gene 3862427..3862690 /gene="yxjJ" /locus_tag="BSU_38930" /old_locus_tag="BSU38930" promotor_-35 3862454..3862457 /Source="Nicolas_upshift_promotors" /id="U3074" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.541458541458541" /psig="0.554445554445554" /xcortree=653 /SigmaFactorBS="ttcttgttatttattgatttagaattttttGAATactttttg gcatttTATCCGTACAATAGAGAGTAccaaaactttttttgggaggtatgtaatatga t" /GFF_Attribute="listShort" /listLong="yxjI, NA, yxjH, NA, S1499, yxjG" /label="promotor_-35" promotor_-10 3862472..3862491 /Source="Nicolas_upshift_promotors" /id="U3074" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.541458541458541" /psig="0.554445554445554" /xcortree=653 /SigmaFactorBS="ttcttgttatttattgatttagaattttttGAATactttttg gcatttTATCCGTACAATAGAGAGTAccaaaactttttttgggaggtatgtaatatga t" /GFF_Attribute="listShort" /listLong="yxjI, NA, yxjH, NA, S1499, yxjG" /label="promotor_-10" upshifts 3862484 /Source="Nicolas_upshifts" /id="U3074" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.541458541458541" /psig="0.554445554445554" /xcortree=653 /SigmaFactorBS="ttcttgttatttattgatttagaattttttGAATactttttg gcatttTATCCGTACAATAGAGAGTAccaaaactttttttgggaggtatgtaatatga t" /GFF_Attribute="listShort" /listLong="yxjI, NA, yxjH, NA, S1499, yxjG" downshifts 3862638 /Source="Nicolas_upshifts" /id="D2022" /incds=0 /nref=4 /ntot=92 /MaxReadThrough="7.33654" /MaxDrop="3.1638" /score="-1.57383757" /energy="-6.2" /TU="U3072,U3073,U3074" /idTUdmin="U3073" /TUdmin="-110" /isTUend="FALSE" downshifts 3862682 /Source="Nicolas_upshifts" /id="D2023" /incds=0 /nref=44 /ntot=188 /MaxReadThrough="5.58502" /MaxDrop="4.5161" /score="-1.57383757" /energy="-6.2" /TU="U3072,U3073,U3074" /idTUdmin="U3073" /TUdmin="-66" /isTUend="FALSE" promotor_-35 3862757..3862766 /Source="Nicolas_upshift_promotors" /id="U3075" /multdbtbs="SigW" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1670 /SigmaFactorBS="gctgctgaatcacgcagccttttaaaattgttttgatttaga gccTGAAACCTTTtcgccacctatCCGTAATTTCATACAAggcaaacccaaaggagac t" /listShort="yxjI, NA, yxjH, NA, S1499, yxjG" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 3862772 /Source="Nicolas_upshifts" /id="U3075" /multdbtbs="SigW" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1670 /SigmaFactorBS="gctgctgaatcacgcagccttttaaaattgttttgatttaga gccTGAAACCTTTtcgccacctatCCGTAATTTCATACAAggcaaacccaaaggagac t" /listShort="yxjI, NA, yxjH, NA, S1499, yxjG" /GFF_Attribute="listLong" promotor_-10 3862778..3862793 /Source="Nicolas_upshift_promotors" /id="U3075" /multdbtbs="SigW" /comp="M9" /sig="SigWXY" /pcomp=1 /psig=1 /xcortree=1670 /SigmaFactorBS="gctgctgaatcacgcagccttttaaaattgttttgatttaga gccTGAAACCTTTtcgccacctatCCGTAATTTCATACAAggcaaacccaaaggagac t" /listShort="yxjI, NA, yxjH, NA, S1499, yxjG" /GFF_Attribute="listLong" /label="promotor_-10" CDS 3862819..3863307 /gene="yxjI" /locus_tag="BSU_38940" /old_locus_tag="BSU38940" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_391773.1" /db_xref="EnsemblGenomes-Gn:BSU38940" /db_xref="EnsemblGenomes-Tr:CAB15920" /db_xref="InterPro:IPR007612" /db_xref="InterPro:IPR025659" /db_xref="SubtiList:BG12539" /db_xref="UniProtKB/Swiss-Prot:P94352" /translation="MIELFMKQKMFSFKDAFHIYDRDEQETFKVEGRFFSLGDSLQMT DSSGKTLVSIEQKLMSLLPRYEISIGGKTVCEVTKKVTFSKPKFVISGLNWEIDGDLW RDEFQLTDGENVRMSVSKKWLSWGDSYHLQIAYEEDVLICTAIAIVLDMVLYNDEDES IF*" gene 3862819..3863307 /gene="yxjI" /locus_tag="BSU_38940" /old_locus_tag="BSU38940" promotor_-35 3863312..3863319 /Source="Nicolas_upshift_promotors" /id="U3076" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.995004995004995" /psig=1 /xcortree=2891 /SigmaFactorBS="cgatgaagatgaaagtattttctaaaaagCATTGACAattga tccaaaagTAATAATATTAAGATAATTGaaatctgaatatgaagttgtaccttatcaa g" /listShort="NA, yxjH, NA, S1499, yxjG" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3863333..3863352 /Source="Nicolas_upshift_promotors" /id="U3076" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.995004995004995" /psig=1 /xcortree=2891 /SigmaFactorBS="cgatgaagatgaaagtattttctaaaaagCATTGACAattga tccaaaagTAATAATATTAAGATAATTGaaatctgaatatgaagttgtaccttatcaa g" /listShort="NA, yxjH, NA, S1499, yxjG" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3863343 /Source="Nicolas_upshifts" /id="U3076" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.995004995004995" /psig=1 /xcortree=2891 /SigmaFactorBS="cgatgaagatgaaagtattttctaaaaagCATTGACAattga tccaaaagTAATAATATTAAGATAATTGaaatctgaatatgaagttgtaccttatcaa g" /listShort="NA, yxjH, NA, S1499, yxjG" /GFF_Attribute="listLong" misc_RNA 3863373..3863479 /gene="mswI" /locus_tag="BSU_misc_RNA_61" /product="S-adenosylmethionine riboswitch" /experiment="publication(s) with functional evidences, PMID:10094622, 12626738, 12910260, 17381305, 18039762" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10094622, 12626738, 12910260, 17381305, 18039762; Product type n: RNA" /function="16.3: Control" gene 3863373..3863479 /gene="mswI" /locus_tag="BSU_misc_RNA_61" downshifts 3863474 /Source="Nicolas_upshifts" /id="D2024" /incds=0 /nref=22 /ntot=102 /MaxReadThrough="7.18775" /MaxDrop="3.7896" /score="9.64734237" /energy="-14.5" /TU="U3075,U3076" /idTUdmin="U3072" /TUdmin=0 /isTUend="TRUE" CDS 3863562..3864695 /gene="yxjH" /locus_tag="BSU_38950" /old_locus_tag="BSU38950" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 12456320, 14563871, 17098890, 17114254; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative methyl-tetrahydrofolate methyltransferase (biofilm formation)" /protein_id="NP_391774.2" /db_xref="EnsemblGenomes-Gn:BSU38950" /db_xref="EnsemblGenomes-Tr:CAB15921" /db_xref="GOA:P42319" /db_xref="InterPro:IPR002629" /db_xref="SubtiList:BG11157" /db_xref="UniProtKB/Swiss-Prot:P42319" /translation="MAQQTNVAGQKTEKQRKAPFRADHVGSLLRSVPVKEARQKKAAG EMTAEQLRDIENQEITRIVEKQKEIGLDVVTDGEFRRSWWHYDFLEGLDGVEPFIPAE GIQFHNTKTKARSIKVTGKLDFTSHPALGDYQFLHEIAGNATPKLTIPSPNMLFFGEK ADKGIYDDQEEYFHDMAQAYKKAIKAFYDAGCRYLQLDDTSWSLFFEDKGREVVRALG GDPETLPAIFAKTINDAVADRPDDLTITMHICRGNFRSTWAASGGYDAVAETILDGLN LDGLFLEYDDDRSGNFDPLRFVKRKDLQIVLGLITSKYGELENPEDVKRRINEAARFV SLDQLCLSPQCGFASTEEGNLLTEEQQWAKLRHVIDIANDVWR*" gene 3863562..3864695 /gene="yxjH" /locus_tag="BSU_38950" /old_locus_tag="BSU38950" S_feature complement(3863835..3864078) /Source="Nicolas_S_feature" /locus_tag="new_3998237_3998480_c" /HighExp="dia15, Diami, H2O2, dia5, C90, Paraq, Sw, BC, LBGstat, Lbtran" /AntisenseName="yxjH" /AntisenseCor="-0.34694665046491102" /AntisenseRegPval="-8.3000000000000007" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.997" /TUlongSig="NA" /TUlongPSig="NA" /label="S1498" promotor_-10 complement(3864073..3864092) /Source="Nicolas_upshift_promotors" /id="U3077" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.982017982017982" /psig="0.997002997002997" /xcortree=2079 /SigmaFactorBS="taacggcagccagcatcatagaaggcttTGATTGCTtttttg tacgcttgGGCCATATCATGAAAGTATTcctcttgatcgtcataaatccctttatccg c" /listShort="S1498" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3864082) /Source="Nicolas_upshifts" /id="U3077" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.982017982017982" /psig="0.997002997002997" /xcortree=2079 /SigmaFactorBS="taacggcagccagcatcatagaaggcttTGATTGCTtttttg tacgcttgGGCCATATCATGAAAGTATTcctcttgatcgtcataaatccctttatccg c" /listShort="S1498" /GFF_Attribute="listLong" promotor_-35 complement(3864107..3864114) /Source="Nicolas_upshift_promotors" /id="U3077" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.982017982017982" /psig="0.997002997002997" /xcortree=2079 /SigmaFactorBS="taacggcagccagcatcatagaaggcttTGATTGCTtttttg tacgcttgGGCCATATCATGAAAGTATTcctcttgatcgtcataaatccctttatccg c" /listShort="S1498" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 3864701..3864708 /Source="Nicolas_upshift_promotors" /id="U3078" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.97002997002997" /psig=1 /xcortree=2892 /SigmaFactorBS="gacattgccaacgatgtgtggagataatctatCATTGACAga aatagaaaatgtGTGAATAATAGATACTATCAgaaaatttaataaaaaggttttcctt a" /listShort="NA, S1499, yxjG" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3864723..3864742 /Source="Nicolas_upshift_promotors" /id="U3078" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.97002997002997" /psig=1 /xcortree=2892 /SigmaFactorBS="gacattgccaacgatgtgtggagataatctatCATTGACAga aatagaaaatgtGTGAATAATAGATACTATCAgaaaatttaataaaaaggttttcctt a" /listShort="NA, S1499, yxjG" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3864729 /Source="Nicolas_upshifts" /id="U3078" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.97002997002997" /psig=1 /xcortree=2892 /SigmaFactorBS="gacattgccaacgatgtgtggagataatctatCATTGACAga aatagaaaatgtGTGAATAATAGATACTATCAgaaaatttaataaaaaggttttcctt a" /listShort="NA, S1499, yxjG" /GFF_Attribute="listLong" misc_RNA 3864764..3864870 /gene="mswJ" /locus_tag="BSU_misc_RNA_62" /product="S-adenosylmethionine riboswitch" /experiment="publication(s) with functional evidences, PMID:10094622, 12626738, 12910260, 17381305, 18039762" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10094622, 12626738, 12910260, 17381305, 18039762; Product type n: RNA" /function="16.3: Control" gene 3864764..3864870 /gene="mswJ" /locus_tag="BSU_misc_RNA_62" downshifts 3864817 /Source="Nicolas_upshifts" /id="D2025" /incds=0 /nref=3 /ntot=21 /MaxReadThrough="8.35488" /MaxDrop="3.50346" /score="29.0146782" /energy="-14.5" /TU="U3075,U3076,U3078" /idTUdmin="U3075" /TUdmin="-1254" /isTUend="FALSE" S_feature 3864871..3864947 /Source="Nicolas_S_feature" /locus_tag="new_3999273_3999349" /HighExp="MG 5, MG t5, T1.0H, MG 10, T1.30H, BMM, T0.30H, T-0.40H, T0.0H, MG 15" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA, SigWXY" /TUshortPSig="1, 1, 1" /TUlongSig="SigA, SigD, SigB, SigWXY" /TUlongPSig="0.554, 1, 1, 1" /label="S1499" CDS 3864948..3866084 /gene="yxjG" /locus_tag="BSU_38960" /old_locus_tag="BSU38960" /function="16.11: Scavenge (Catabolism)" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 12456320, 14563871, 17098890, 17114254, 21749987; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative methyltetrahydrofolate methyltransferase (biofilm formation)" /protein_id="NP_391775.3" /db_xref="EnsemblGenomes-Gn:BSU38960" /db_xref="EnsemblGenomes-Tr:CAB15922" /db_xref="GOA:P42318" /db_xref="InterPro:IPR002629" /db_xref="SubtiList:BG11156" /db_xref="UniProtKB/Swiss-Prot:P42318" /translation="MSQQTTPAEQKSLQRKKPPFRADQVGSLLRSEPVKKARLQKAAG EMTAEQLRQIENDEIIRIVEKQKETGLNVVTDGEFRRAWWHFDFLENLDGVEPFTPEQ GIQFHNVQTKARGIKVTGDIDFSTHPMLEDYSFLHSIAGDATPKMTIPSPNMLFFRGK LEKDEYKNDYQLFQHDVSKAYKKAIQAFYDRGCRYLQLDDTAWAVFLSEKGLKQIEAF GTTPDELRQLFAKSINDAIADRPDDLTVTMHICRGNFQSTWTAEGGYDAAAETIFDGL NLDGLFLEYDDSRSGGFEPLRYVKRSDLQLVLGLVTSKFGELENPDDVKRRIEEASRY VSLDQLCLSPQCGFASTEEGNKLTEEQQWAKLRHVVEIANDVWK*" gene 3864948..3866084 /gene="yxjG" /locus_tag="BSU_38960" /old_locus_tag="BSU38960" downshifts 3866071 /Source="Nicolas_upshifts" /id="D2026" /incds=0 /nref=81 /ntot=187 /MaxReadThrough="4.24668" /MaxDrop="5.8124" /score="11.1243305" /energy="-12.8" /TU="U3076,U3078" /idTUdmin="U3075" /TUdmin=0 /isTUend="TRUE" CDS complement(3866137..3866910) /gene="yxjF" /locus_tag="BSU_38970" /old_locus_tag="BSU38970" /EC_number="1.1.1.-" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative hydroxyacid dehydrogenase" /protein_id="NP_391776.2" /db_xref="EnsemblGenomes-Gn:BSU38970" /db_xref="EnsemblGenomes-Tr:CAB15923" /db_xref="GOA:P42317" /db_xref="InterPro:IPR002347" /db_xref="InterPro:IPR011294" /db_xref="InterPro:IPR020904" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG11155" /db_xref="UniProtKB/Swiss-Prot:P42317" /translation="MRKQVALVTGAAGGIGFEIAREFAREGASVIVSDLRPEACEKAA SKLAEEGFDAAAIPYDVTKEAQVADTVNVIQKQYGRLDILVNNAGIQHVAPIEEFPTD TFEQLIKVMLTAPFIAMKHVFPIMKKQQFGRIINIASVNGLVGFAGKSAYNSAKHGVI GLTKVGALEGAPHGITVNALCPGYVDTQLVRNQLSDLSKTRNVPYDSVLEQVIFPLVP QKRLLSVKEIADYAVFLASEKAKGVTGQAVVLDGGYTAQ*" gene complement(3866137..3866910) /gene="yxjF" /locus_tag="BSU_38970" /old_locus_tag="BSU38970" downshifts complement(3866147) /Source="Nicolas_upshifts" /id="D2027" /incds=0 /nref=23 /ntot=63 /MaxReadThrough="0.65" /MaxDrop="6.97604" /score="24.6585594" /energy="-12.8" /TU="NA" /idTUdmin="U3079" /TUdmin=0 /isTUend="TRUE" CDS complement(3866927..3867577) /gene="scoB" /locus_tag="BSU_38980" /old_locus_tag="BSU38980" /EC_number="2.8.3.5" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 17363272, 22720735; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="acetoacetyl CoA-transferase (subunit B)" /protein_id="NP_391777.1" /db_xref="EnsemblGenomes-Gn:BSU38980" /db_xref="EnsemblGenomes-Tr:CAB15924" /db_xref="GOA:P42316" /db_xref="InterPro:IPR004164" /db_xref="InterPro:IPR004165" /db_xref="InterPro:IPR012791" /db_xref="PDB:3CDK" /db_xref="SubtiList:BG11154" /db_xref="UniProtKB/Swiss-Prot:P42316" /translation="MKEARKRMVKRAVQEIKDGMNVNLGIGMPTLVANEIPDGVHVML QSENGLLGIGPYPLEGTEDADLINAGKETITEVTGASYFDSAESFAMIRGGHIDLAIL GGMEVSEQGDLANWMIPGKMVKGMGGAMDLVNGAKRIVVIMEHVNKHGESKVKKTCSL PLTGQKVVHRLITDLAVFDFVNGRMTLTELQDGVTIEEVYEKTEADFAVSQSVLNS*" gene complement(3866927..3867577) /gene="scoB" /locus_tag="BSU_38980" /old_locus_tag="BSU38980" CDS complement(3867574..3868290) /gene="scoA" /locus_tag="BSU_38990" /old_locus_tag="BSU38990" /EC_number="2.8.3.5" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 17363272; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="acetoacetyl CoA-transferase (subunit A)" /protein_id="NP_391778.1" /db_xref="EnsemblGenomes-Gn:BSU38990" /db_xref="EnsemblGenomes-Tr:CAB15925" /db_xref="GOA:P42315" /db_xref="InterPro:IPR004163" /db_xref="InterPro:IPR004165" /db_xref="InterPro:IPR012792" /db_xref="PDB:3CDK" /db_xref="SubtiList:BG11153" /db_xref="UniProtKB/Swiss-Prot:P42315" /translation="MGKVLSSSKEAAKLIHDGDTLIAGGFGLCGIPEQLILSIRDQGV KDLTVVSNNCGVDDWGLGLLLANKQIKKMIASYVGENKIFERQFLSGELEVELVPQGT LAERIRAGGAGIPGFYTATGVGTSIAEGKEHKTFGGRTYVLERGITGDVAIVKAWKAD TMGNLIFRKTARNFNPIAAMAGKITIAEAEEIVEAGELDPDHIHTPGIYVQHVVLGAS QEKRIEKRTVQQASGKGEAK*" gene complement(3867574..3868290) /gene="scoA" /locus_tag="BSU_38990" /old_locus_tag="BSU38990" CDS complement(3868314..3869732) /gene="yxjC" /locus_tag="BSU_39000" /old_locus_tag="BSU39000" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406, 22720735; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative acid metabolite permease" /protein_id="NP_391779.3" /db_xref="EnsemblGenomes-Gn:BSU39000" /db_xref="EnsemblGenomes-Tr:CAB15926" /db_xref="GOA:P42314" /db_xref="SubtiList:BG11152" /db_xref="UniProtKB/Swiss-Prot:P42314" /translation="MELIIILLALGLLMFTAYRGFSVILFAPICALFAVLLTDPSHVL PFFSSIFMEKMAGFIKLYFPVFLLGAIFGKVVEMAGLAASIAKTIVRLVGAKRAILAI VLMGAVLTYSGVSLFVVVFAVYPFAKNMFQEANIPKRLIPGTIALGAFTFTMDALPGT PQIQNVIPTSFFKTDIYAAPWLGLMGAVIVLAAGMLYLESRRKKAQASGEGYGGFDSQ NAPAPESIESAAEPDKSPIRHALAFVPLILVGAVNKYFTIYLPKWYPNGFDFSSIGLK EFGRLDISSAAAIWSVEIALVIGIITTILFDWRSVFAQLKEGLNEGIGGALLASMNTG AEYGFGGIIAALPGFHKLSSGISHTFTDPLVNGAVTTTALAGITGSASGGMGIALSAM SEQYLQAIQAYNIPPEVMHRVISMASGGMDTLPHNGAVITLLAVTGLTHRQSYRDIFA ITLIKTAAVFAVIAIYSLTGLV*" gene complement(3868314..3869732) /gene="yxjC" /locus_tag="BSU_39000" /old_locus_tag="BSU39000" promotor_-10 complement(3868900..3868918) /Source="Nicolas_upshift_promotors" /id="U3079" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.996003996003996" /psig="0.996003996003996" /xcortree=762 /SigmaFactorBS="gtgaataaatatttcaccatttacctgccaaagtggtatcCG AATGgatttgatttttcttCCATAGGATTAAAGGAGTTcggcaggcttgatatttctt c" /listShort="scoA, scoB, yxjF" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3868919) /Source="Nicolas_upshifts" /id="U3079" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.996003996003996" /psig="0.996003996003996" /xcortree=762 /SigmaFactorBS="gtgaataaatatttcaccatttacctgccaaagtggtatcCG AATGgatttgatttttcttCCATAGGATTAAAGGAGTTcggcaggcttgatatttctt c" /listShort="scoA, scoB, yxjF" /GFF_Attribute="listLong" promotor_-35 complement(3868934..3868939) /Source="Nicolas_upshift_promotors" /id="U3079" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.996003996003996" /psig="0.996003996003996" /xcortree=762 /SigmaFactorBS="gtgaataaatatttcaccatttacctgccaaagtggtatcCG AATGgatttgatttttcttCCATAGGATTAAAGGAGTTcggcaggcttgatatttctt c" /listShort="scoA, scoB, yxjF" /GFF_Attribute="listLong" /label="promotor_-35" S_feature complement(3869733..3869817) /Source="Nicolas_S_feature" /locus_tag="new_4004135_4004219_c" /HighExp="S5, S4, S6, S3, S7, M9-stat, B60, S8, T4.0H, T5.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigEF" /TUshortPSig="0.993" /TUlongSig="NA" /TUlongPSig="NA" /label="S1500" promotor_-10 complement(3869801..3869819) /Source="Nicolas_upshift_promotors" /id="U3080" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp="0.993006993006993" /psig="0.993006993006993" /xcortree=1046 /SigmaFactorBS="ggaaagctccgaaaaaaggagctttccttttttaatcGGAAT AgttggcccacgcttcTCGTACATATGGAAAGGGGacggaaacagccgatgcggacag g" /listShort="S1500, yxjC, scoA, scoB, yxjF" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3869817) /Source="Nicolas_upshifts" /id="U3080" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp="0.993006993006993" /psig="0.993006993006993" /xcortree=1046 /SigmaFactorBS="ggaaagctccgaaaaaaggagctttccttttttaatcGGAAT AgttggcccacgcttcTCGTACATATGGAAAGGGGacggaaacagccgatgcggacag g" /listShort="S1500, yxjC, scoA, scoB, yxjF" /GFF_Attribute="listLong" promotor_-35 complement(3869835..3869840) /Source="Nicolas_upshift_promotors" /id="U3080" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp="0.993006993006993" /psig="0.993006993006993" /xcortree=1046 /SigmaFactorBS="ggaaagctccgaaaaaaggagctttccttttttaatcGGAAT AgttggcccacgcttcTCGTACATATGGAAAGGGGacggaaacagccgatgcggacag g" /listShort="S1500, yxjC, scoA, scoB, yxjF" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3869886..3870734) /gene="rlmA" /locus_tag="BSU_39010" /old_locus_tag="BSU39010" /EC_number="2.1.1.188" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2b: Function from indirect experimental evidences (e.g. phenotypes); PubMedId: 11967079, 14999102, 18406425, 23716046; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="23S rRNA m(1)G748 methyltransferase (class II)" /protein_id="NP_391780.1" /db_xref="EnsemblGenomes-Gn:BSU39010" /db_xref="EnsemblGenomes-Tr:CAB15927" /db_xref="GOA:P42313" /db_xref="InterPro:IPR013216" /db_xref="InterPro:IPR016718" /db_xref="InterPro:IPR029063" /db_xref="SubtiList:BG11151" /db_xref="UniProtKB/Swiss-Prot:P42313" /translation="MKRTVDFSMFRCPLCDSSMDAASGKSLICTERGHTFDLSRHGYV NFLTKPVKTSYGAELFEARSRLIGECGFFDPLHDAIAELISHPKSGHEAFTILDSGCG EGSHLNALCGFDYAGKAAIGTGIDLSKDGILKASKAFKDLMWAVADVARAPFHDRQFD VVLSIFSPSNYAEFHRLLKNDGMLIKVVPRSDYLIELRQFLYTDSPRRTYSNTAAVER FTANAAHSRPVRLRYVKTLDQQAIHWLLKMTPLAWSAPKDRVSLLKEMKSADITVDVD ILIGMK*" gene complement(3869886..3870734) /gene="rlmA" /locus_tag="BSU_39010" /old_locus_tag="BSU39010" downshifts complement(3869896) /Source="Nicolas_upshifts" /id="D2028" /incds=0 /nref=54 /ntot=218 /MaxReadThrough="1.618" /MaxDrop="4.63737" /score="17.0758624" /energy="-15.1" /TU="NA" /idTUdmin="U3081" /TUdmin="-9" /isTUend="TRUE" S_feature complement(3870735..3870920) /Source="Nicolas_S_feature" /locus_tag="new_4005137_4005322_c" /HighExp="B60, LBGstat, LPhT, M9-stat, C30, T0.30H, HPh, Oxctl, Heat, LBGtran" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigD" /TUshortPSig="1, 0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S1501" promotor_-10 complement(3870909..3870928) /Source="Nicolas_upshift_promotors" /id="U3081" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.927072927072927" /psig=1 /xcortree=2742 /SigmaFactorBS="agcatgtcagtactgatttttcttcactataaGGTTCcagct cctggatattTGTTGTATGATGGAAACGGGgaaacccatacagcagaaagggagtttt t" /listShort="S1501, yxjB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3870920) /Source="Nicolas_upshifts" /id="U3081" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.927072927072927" /psig=1 /xcortree=2742 /SigmaFactorBS="agcatgtcagtactgatttttcttcactataaGGTTCcagct cctggatattTGTTGTATGATGGAAACGGGgaaacccatacagcagaaagggagtttt t" /listShort="S1501, yxjB" /GFF_Attribute="listLong" S_feature complement(3870922..3871647) /Source="Nicolas_S_feature" /locus_tag="new_4005324_4006049_c" /HighExp="LBGstat, C30, GM 25, Heat, GM 10, GM 45, GM 60, GM 90, T0.30H, GM 120" /AntisenseName="NA" /AntisenseCor="0.20859849915331599" /AntisenseRegPval="-3.2" /CDS_PredictionProba="NA" /TUshortSig="SigD" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S1502" promotor_-35 complement(3870944..3870948) /Source="Nicolas_upshift_promotors" /id="U3081" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.927072927072927" /psig=1 /xcortree=2742 /SigmaFactorBS="agcatgtcagtactgatttttcttcactataaGGTTCcagct cctggatattTGTTGTATGATGGAAACGGGgaaacccatacagcagaaagggagtttt t" /listShort="S1501, yxjB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 3871082..3871089 /Source="Nicolas_upshift_promotors" /id="U3082" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.478521478521479" /psig="0.996003996003996" /xcortree=2667 /SigmaFactorBS="taaattttattattgtgaaaatagttaaaaaGGTTGATTttc aaaaagtgaAAGGATAAAATACTGCTATCatcttagaaaaagacattcttgtatatga t" /listShort="NA, S1503, yxjA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3871102..3871121 /Source="Nicolas_upshift_promotors" /id="U3082" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.478521478521479" /psig="0.996003996003996" /xcortree=2667 /SigmaFactorBS="taaattttattattgtgaaaatagttaaaaaGGTTGATTttc aaaaagtgaAAGGATAAAATACTGCTATCatcttagaaaaagacattcttgtatatga t" /listShort="NA, S1503, yxjA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3871111 /Source="Nicolas_upshifts" /id="U3082" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.478521478521479" /psig="0.996003996003996" /xcortree=2667 /SigmaFactorBS="taaattttattattgtgaaaatagttaaaaaGGTTGATTttc aaaaagtgaAAGGATAAAATACTGCTATCatcttagaaaaagacattcttgtatatga t" /listShort="NA, S1503, yxjA" /GFF_Attribute="listLong" misc_RNA 3871121..3871223 /gene="gswB" /locus_tag="BSU_misc_RNA_63" /product="guanine riboswitch" /experiment="publication(s) with functional evidences, PMID:12787499, 15549109, 18072940, 19603494, 20022916, 20200045, 20204714, 21439477" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12787499, 15549109, 18072940, 19603494, 20022916, 20200045, 20204714, 21439477; Product type n: RNA" gene 3871121..3871223 /gene="gswB" /locus_tag="BSU_misc_RNA_63" S_feature 3871224..3871327 /Source="Nicolas_S_feature" /locus_tag="new_4005626_4005729" /HighExp="C90, G180, M40t45, dia15, LBGexp, Lbexp, Lbtran, G135, Mt0, Oxctl" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.996" /TUlongSig="NA" /TUlongPSig="NA" /label="S1503" promotor_-35 3871299..3871305 /Source="Nicolas_upshift_promotors" /id="U3083" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=809 /SigmaFactorBS="tcacactttctgcacttccagaatttgtgaAGGATAAgagct ttttttgtTTCCATAATAACcctcataggagttgctatcatgtactttttactaaacc t" /listShort="yxjA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3871319..3871330 /Source="Nicolas_upshift_promotors" /id="U3083" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=809 /SigmaFactorBS="tcacactttctgcacttccagaatttgtgaAGGATAAgagct ttttttgtTTCCATAATAACcctcataggagttgctatcatgtactttttactaaacc t" /listShort="yxjA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3871329 /Source="Nicolas_upshifts" /id="U3083" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp=1 /psig=1 /xcortree=809 /SigmaFactorBS="tcacactttctgcacttccagaatttgtgaAGGATAAgagct ttttttgtTTCCATAATAACcctcataggagttgctatcatgtactttttactaaacc t" /listShort="yxjA" /GFF_Attribute="listLong" CDS 3871350..3872543 /gene="nupG" /locus_tag="BSU_39020" /old_locus_tag="BSU39020" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2b: Function from indirect experimental evidences (e.g. phenotypes); PubMedId: 12787499, 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="purine nucleoside transporter" /protein_id="NP_391781.2" /db_xref="EnsemblGenomes-Gn:BSU39020" /db_xref="EnsemblGenomes-Tr:CAB15928" /db_xref="GOA:P42312" /db_xref="InterPro:IPR002668" /db_xref="InterPro:IPR008276" /db_xref="InterPro:IPR011657" /db_xref="InterPro:IPR018270" /db_xref="SubtiList:BG11150" /db_xref="UniProtKB/Swiss-Prot:P42312" /translation="MYFLLNLVGLIVIMAVVFLCSPQKKKIKWRPIITLIVLELLITW FMLGTKVGSWAIGKIGDFFTWLIACASDGIAFAFPSVMANETVDFFFSALLPIIFIVT FFDILTYFGILPWLIDKIGWVISKASRLPKLESFFSIQMMFLGNTEALAVIRQQLTVL SNNRLLTFGLMSMSSISGSIIGSYLSMVPATYVFTAIPLNCLNALIIANLLNPVHVPE DEDIIYTPPKEEKKDFFSTISNSMLVGMNMVIVILAMVIGYVALTSAVNGILGVFVHG LTIQTIFAYLFSPFAFLLGLPVHDAMYVAQLMGMKLATNEFVAMLDLKNNLKSLPPHT VAVATTFLTSFANFSTVGMIYGTYNSILDGEKSTVIGRNVWKLLVSGIAVSLLSAAIV GLFVW*" gene 3871350..3872543 /gene="nupG" /locus_tag="BSU_39020" /old_locus_tag="BSU39020" promotor_-10 complement(3871634..3871652) /Source="Nicolas_upshift_promotors" /id="U3084" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=2848 /SigmaFactorBS="cgattttatcaatcagccaaggcaaaatgccgaaatacGTTA AAATatcaaagaatgtGACGATAAAGATAATTGGAagaagcgcactaaagaaaaagtc t" /listShort="S1502, S1501, yxjB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3871650) /Source="Nicolas_upshifts" /id="U3084" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=2848 /SigmaFactorBS="cgattttatcaatcagccaaggcaaaatgccgaaatacGTTA AAATatcaaagaatgtGACGATAAAGATAATTGGAagaagcgcactaaagaaaaagtc t" /listShort="S1502, S1501, yxjB" /GFF_Attribute="listLong" promotor_-35 complement(3871665..3871672) /Source="Nicolas_upshift_promotors" /id="U3084" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=2848 /SigmaFactorBS="cgattttatcaatcagccaaggcaaaatgccgaaatacGTTA AAATatcaaagaatgtGACGATAAAGATAATTGGAagaagcgcactaaagaaaaagtc t" /listShort="S1502, S1501, yxjB" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 3872319 /Source="Nicolas_upshifts" /id="D2029" /incds=1 /nref=1 /ntot=58 /MaxReadThrough="5.88279" /MaxDrop="2.4159" /score="8.04757856" /energy="-16.6" /TU="U3082,U3083" /idTUdmin="U3082" /TUdmin="-220" /isTUend="FALSE" downshifts 3872539 /Source="Nicolas_upshifts" /id="D2030" /incds=0 /nref=71 /ntot=204 /MaxReadThrough="2.7474" /MaxDrop="4.05925" /score="8.04757856" /energy="-16.6" /TU="NA" /idTUdmin="U3082" /TUdmin=0 /isTUend="TRUE" CDS complement(3872585..3873013) /gene="yxiTc" /locus_tag="BSU_39029" /old_locus_tag="BSU39029" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /pseudo /codon_start=1 /transl_table=11 /product="conserved protein of unknown function (C-terminus)" /translation="KTKKQANSRALKREYQTSFSVKYNAAGKLSIQTLNYIYSGGAHG LTSVQSFNYDLKAQKRVTLDQILNTKTKVSKTRDYLYSYIKKHDVLFFSDVKKEDITL NRDTMFYFTANGIAIVFGQYDLGPYAAGIRDVQVPASIYQ*" gene complement(3872585..3873013) /gene="yxiTc" /locus_tag="BSU_39029" /old_locus_tag="BSU39029" /pseudo CDS complement(3873014..3873256) /gene="yxiTn" /locus_tag="BSU_39030" /old_locus_tag="BSU39030" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /pseudo /codon_start=1 /transl_table=11 /product="conserved protein of unknown function (N-terminus)" /db_xref="PSEUDO:CAB15929.2" /db_xref="SubtiList:BG11149" /db_xref="UniProtKB/Swiss-Prot:P42311" /translation="MKWNNMLKAAGIAVLLFSVFAYAAPSLKAVQAKTPTVSTHTYKK IKELTYPQVHHVGNAAFEKKINQELKAYMNNRIRNT*" gene complement(3873014..3873256) /gene="yxiTn" /locus_tag="BSU_39030" /old_locus_tag="BSU39030" /pseudo S_feature complement(3873257..3873320) /Source="Nicolas_S_feature" /locus_tag="new_4007659_4007722_c" /HighExp="T2.30H, S6, Etha, T3.30H, S5, BT, T3.0H, T4.0H, T2.0H, T5.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigWXY" /TUshortPSig="0.942" /TUlongSig="NA" /TUlongPSig="NA" /label="S1504" promotor_-10 complement(3873309..3873324) /Source="Nicolas_upshift_promotors" /id="U3085" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp="0.942057942057942" /psig="0.942057942057942" /xcortree=757 /SigmaFactorBS="tctttttttattggaaaaatcatgctgttagacctAGAAACT TCTttcgatttaatCAGTCTATAAAAGTGTgtattgcttaaataagggaatgataaac a" /listShort="S1504, yxiT, yxiT" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3873320) /Source="Nicolas_upshifts" /id="U3085" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp="0.942057942057942" /psig="0.942057942057942" /xcortree=757 /SigmaFactorBS="tctttttttattggaaaaatcatgctgttagacctAGAAACT TCTttcgatttaatCAGTCTATAAAAGTGTgtattgcttaaataagggaatgataaac a" /listShort="S1504, yxiT, yxiT" /GFF_Attribute="listLong" promotor_-35 complement(3873336..3873345) /Source="Nicolas_upshift_promotors" /id="U3085" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp="0.942057942057942" /psig="0.942057942057942" /xcortree=757 /SigmaFactorBS="tctttttttattggaaaaatcatgctgttagacctAGAAACT TCTttcgatttaatCAGTCTATAAAAGTGTgtattgcttaaataagggaatgataaac a" /listShort="S1504, yxiT, yxiT" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 3873353 /Source="Nicolas_upshifts" /id="D2031" /incds=0 /nref=10 /ntot=69 /MaxReadThrough="0.814549999999999" /MaxDrop="3.89525" /score="14.5338714" /energy="-6.9" /TU="NA" /idTUdmin="U3082" /TUdmin=814 /isTUend="FALSE" CDS complement(3873401..3873691) /gene="yxiS" /locus_tag="BSU_39040" /old_locus_tag="BSU39040" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_391783.2" /db_xref="EnsemblGenomes-Gn:BSU39040" /db_xref="EnsemblGenomes-Tr:CAB15930" /db_xref="SubtiList:BG11148" /db_xref="UniProtKB/Swiss-Prot:P42310" /translation="MNEKQLTEAYERDENMMILVFAQWCVNHDLDPMELYAKAYPQQK LNESLKKTMDDLVVPKHEAEHIPDQTVIAVLEMFGNTDLAQALHEAISGRKQ*" gene complement(3873401..3873691) /gene="yxiS" /locus_tag="BSU_39040" /old_locus_tag="BSU39040" downshifts complement(3873407) /Source="Nicolas_upshifts" /id="D2032" /incds=0 /nref=168 /ntot=241 /MaxReadThrough="3.10756" /MaxDrop="6.10709" /score="16.5130207" /energy="-6.9" /TU="NA" /idTUdmin="U3086" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(3873716..3873735) /Source="Nicolas_upshift_promotors" /id="U3086" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.96103896103896" /psig="0.995004995004995" /xcortree=1926 /SigmaFactorBS="aggcatttatcgatgcggttgctgctcatcgccattgGGATA GACgaatttgatcggcTCCTGTATCTTTAAGGAAGAtacttttcataaggagcatgac a" /listShort="yxiS" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3873733) /Source="Nicolas_upshifts" /id="U3086" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.96103896103896" /psig="0.995004995004995" /xcortree=1926 /SigmaFactorBS="aggcatttatcgatgcggttgctgctcatcgccattgGGATA GACgaatttgatcggcTCCTGTATCTTTAAGGAAGAtacttttcataaggagcatgac a" /listShort="yxiS" /GFF_Attribute="listLong" CDS complement(3873741..3875801) /gene="katE" /locus_tag="BSU_39050" /old_locus_tag="BSU39050" /EC_number="1.11.1.6" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:7559348, 8931328, 16151211" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7559348, 8931328, 16151211; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="catalase 2" /protein_id="NP_391784.2" /db_xref="EnsemblGenomes-Gn:BSU39050" /db_xref="EnsemblGenomes-Tr:CAB15931" /db_xref="GOA:P42234" /db_xref="InterPro:IPR002226" /db_xref="InterPro:IPR002818" /db_xref="InterPro:IPR010582" /db_xref="InterPro:IPR011614" /db_xref="InterPro:IPR018028" /db_xref="InterPro:IPR020835" /db_xref="InterPro:IPR024708" /db_xref="InterPro:IPR024712" /db_xref="InterPro:IPR029062" /db_xref="InterPro:IPR037060" /db_xref="SubtiList:BG11102" /db_xref="UniProtKB/Swiss-Prot:P42234" /translation="MSDDQNKRVNEHSKDEQLEQYRTDNSGKKMTTNQGLRVSEDEHS LKAGVRGPTLMEDFHFREKMTHFDHERIPERVVHARGFGVHGFFQVYEPMTEYTRAKF LQDPSVKTPVFVRFSTVAGSKGSADTVRDARGFATKFYTEEGNYDLVGNNIPVFFIQD AIKFPDLVHAFKPEPHNEMPQAATAHDTFWDFVANNPESAHMVMWTMSDRGIPRSYRM MEGFGVHTFRFVNEQGKARFVKFHWKPVLGVHSLVWDEAQKIAGKDPDFHRRDLWETI ENGGKVEYELGVQMIDEEDEFKFDFDILDPTKLWPEELVPVKIIGKMTLNRNQDNVFA ETEQVAFHPGNVVPGIDFTNDPLLQGRLFSYTDTQLIRLGGPNFHEIPINRPVCPFHN NQYDGYHRMTINKGPVAYHKNSLQNNDPSPATAEEGGYVHYQEKVEGKKIRQRSDSFN DYYSQAKLFWNSMSPVEKQHIISAFCFEVGKVKSKDVQRQVVDVFSNVDADLAEEIAK GVGVAAPAKRKASKEILTSPALSQARTVKTASTRKVAVLAGNGFHEKELQTVLEALKQ EGITVDIISQNLGYMTSGSGQQLEASGTFLTVDSVLYDAVYAAGGLELKDNKQAMAFI REAYNHYKAIGAANEGIDLLQSSVGTTEGLGIVTAKDEPDYTAFSKAFIDAVAAHRHW DRRI*" gene complement(3873741..3875801) /gene="katE" /locus_tag="BSU_39050" /old_locus_tag="BSU39050" promotor_-35 complement(3873749..3873756) /Source="Nicolas_upshift_promotors" /id="U3086" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.96103896103896" /psig="0.995004995004995" /xcortree=1926 /SigmaFactorBS="aggcatttatcgatgcggttgctgctcatcgccattgGGATA GACgaatttgatcggcTCCTGTATCTTTAAGGAAGAtacttttcataaggagcatgac a" /listShort="yxiS" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(3875830..3875848) /Source="Nicolas_upshift_promotors" /id="U3087" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=220 /SigmaFactorBS="caaaaatcctaatgagcggattagcAGTTTATatgaagaacg ccacGGGTAAATGTGCTGTAGAAtgtttcgttttaaaaagggggagcagacatgagtg a" /listShort="katE, yxiS" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3875834) /Source="Nicolas_upshifts" /id="U3087" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=220 /SigmaFactorBS="caaaaatcctaatgagcggattagcAGTTTATatgaagaacg ccacGGGTAAATGTGCTGTAGAAtgtttcgttttaaaaagggggagcagacatgagtg a" /listShort="katE, yxiS" /GFF_Attribute="listLong" promotor_-35 complement(3875863..3875869) /Source="Nicolas_upshift_promotors" /id="U3087" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=220 /SigmaFactorBS="caaaaatcctaatgagcggattagcAGTTTATatgaagaacg ccacGGGTAAATGTGCTGTAGAAtgtttcgttttaaaaagggggagcagacatgagtg a" /listShort="katE, yxiS" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 3875894..3875899 /Source="Nicolas_upshift_promotors" /id="U3088" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1049 /SigmaFactorBS="cgttcttcatataaactgctaatccgctcattaggatttttG GTCTAcatataaatatgcggTCATACACATTTGAAATAAgccttcttcacagaaagaa a" /listShort="S1505, citH, S1506" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 3875913 /Source="Nicolas_upshifts" /id="U3088" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1049 /SigmaFactorBS="cgttcttcatataaactgctaatccgctcattaggatttttG GTCTAcatataaatatgcggTCATACACATTTGAAATAAgccttcttcacagaaagaa a" /listShort="S1505, citH, S1506" /GFF_Attribute="listLong" promotor_-10 3875915..3875933 /Source="Nicolas_upshift_promotors" /id="U3088" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1049 /SigmaFactorBS="cgttcttcatataaactgctaatccgctcattaggatttttG GTCTAcatataaatatgcggTCATACACATTTGAAATAAgccttcttcacagaaagaa a" /listShort="S1505, citH, S1506" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 3875927..3876001 /Source="Nicolas_S_feature" /locus_tag="new_4010329_4010403" /HighExp="S6, S5, S4, S8, S7, S3, M9-stat, LoTm, BT, T5.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigEF" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1505" CDS 3876002..3877282 /gene="citH" /locus_tag="BSU_39060" /old_locus_tag="BSU39060" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:8892821, 11053381, 15849754, 16850406, 18556792" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8892821, 11053381, 15849754, 16850406, 18556792; Product type t : transporter" /codon_start=1 /transl_table=11 /product="secondary transporter of divalent metal ions/citrate complexes" /protein_id="NP_391785.2" /db_xref="EnsemblGenomes-Gn:BSU39060" /db_xref="EnsemblGenomes-Tr:CAB15932" /db_xref="GOA:P42308" /db_xref="InterPro:IPR004680" /db_xref="InterPro:IPR014738" /db_xref="SubtiList:BG11146" /db_xref="UniProtKB/Swiss-Prot:P42308" /translation="MLAILGFVMMIVFMYLIMSNRLSALIALIVVPIVFALISGFGKD LGEMMIQGVTDLAPTGIMLLFAILYFGIMIDSGLFDPLIAKILSFVKGDPLKIAVGTA VLTMTISLDGDGTTTYMITIAAMLPLYKRLGMNRLVLAGIAMLGSGVMNIIPWGGPTA RVLASLKLDTSEVFTPLIPAMIAGILWVIAVAYILGKKERKRLGVISIDHAPSSDPEA APLKRPALQWFNLLLTVALMAALITSLLPLPVLFMTAFAVALMVNYPNVKEQQKRISA HAGNALNVVSMVFAAGIFTGILSGTKMVDAMAHSLVSLIPDAMGPHLPLITAIVSMPF TFFMSNDAFYFGVLPIIAEAASAYGIDAAEIGRASLLGQPVHLLSPLVPSTYLLVGMA GVSFGDHQKFTIKWAVGTTIVMTIAALLIGIISF*" gene 3876002..3877282 /gene="citH" /locus_tag="BSU_39060" /old_locus_tag="BSU39060" S_feature 3877283..3877422 /Source="Nicolas_S_feature" /locus_tag="new_4011685_4011824" /HighExp="S6, S5, S4, S8, S7, S3, M9-stat, BT, T5.0H, T4.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.382965" /TUshortSig="SigEF" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1506" downshifts 3877379 /Source="Nicolas_upshifts" /id="D2033" /incds=0 /nref=3 /ntot=26 /MaxReadThrough="2.69139" /MaxDrop="3.50434" /score="10.8797157" /energy="-9" /TU="NA" /idTUdmin="U3088" /TUdmin=0 /isTUend="TRUE" CDS complement(3877440..3878168) /gene="bglS" /locus_tag="BSU_39070" /old_locus_tag="BSU39070" /EC_number="3.2.1.73" /EC_number="3.2.1.6" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:1369198, 3106158, 7704256, 20600285, 25355936" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1369198, 3106158, 7704256, 20600285, 25355936; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="endo-beta-1,3-1,4 glucanase" /protein_id="NP_391786.1" /db_xref="EnsemblGenomes-Gn:BSU39070" /db_xref="EnsemblGenomes-Tr:CAB15943" /db_xref="GOA:P04957" /db_xref="InterPro:IPR000757" /db_xref="InterPro:IPR008263" /db_xref="InterPro:IPR008264" /db_xref="InterPro:IPR013320" /db_xref="PDB:3O5S" /db_xref="SubtiList:BG10476" /db_xref="UniProtKB/Swiss-Prot:P04957" /translation="MPYLKRVLLLLVTGLFMSLFAVTATASAQTGGSFFDPFNGYNSG FWQKADGYSNGNMFNCTWRANNVSMTSLGEMRLALTSPAYNKFDCGENRSVQTYGYGL YEVRMKPAKNTGIVSSFFTYTGPTDGTPWDEIDIEFLGKDTTKVQFNYYTNGAGNHEK IVDLGFDAANAYHTYAFDWQPNSIKWYVDGQLKHTATNQIPTTPGKIMMNLWNGTGVD EWLGSYNGVNPLYAHYDWVRYTKK*" gene complement(3877440..3878168) /gene="bglS" /locus_tag="BSU_39070" /old_locus_tag="BSU39070" downshifts complement(3877457) /Source="Nicolas_upshifts" /id="D2034" /incds=0 /nref=64 /ntot=139 /MaxReadThrough="1.52649" /MaxDrop="6.38109" /score="-8.35070051" /energy="-16.3" /TU="NA" /idTUdmin="U3089" /TUdmin="-2" /isTUend="TRUE" promotor_-10 complement(3878199..3878218) /Source="Nicolas_upshift_promotors" /id="U3089" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.621378621378621" /psig=1 /xcortree=366 /SigmaFactorBS="tagtaagattcgatattatcattattttgacCGATGTTCcct tttaaaagaaTCATGTAAGATCAACATAGAaaacgctttcaatgaaaggggaatgcca a" /listShort="bglS" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3878210) /Source="Nicolas_upshifts" /id="U3089" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.621378621378621" /psig=1 /xcortree=366 /SigmaFactorBS="tagtaagattcgatattatcattattttgacCGATGTTCcct tttaaaagaaTCATGTAAGATCAACATAGAaaacgctttcaatgaaaggggaatgcca a" /listShort="bglS" /GFF_Attribute="listLong" promotor_-35 complement(3878232..3878239) /Source="Nicolas_upshift_promotors" /id="U3089" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.621378621378621" /psig=1 /xcortree=366 /SigmaFactorBS="tagtaagattcgatattatcattattttgacCGATGTTCcct tttaaaagaaTCATGTAAGATCAACATAGAaaacgctttcaatgaaaggggaatgcca a" /listShort="bglS" /GFF_Attribute="listLong" /label="promotor_-35" S_feature complement(3878356..3878463) /Source="Nicolas_S_feature" /locus_tag="new_4012758_4012865_c" /HighExp="Sw, LPhT, T0.30H, M0t90, M9-stat, M40t90, Lbtran, Lbstat, S2, T2.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="1, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S1507" downshifts complement(3878399) /Source="Nicolas_upshifts" /id="D2035" /incds=0 /nref=21 /ntot=184 /MaxReadThrough="3.35114" /MaxDrop="4.38508" /score="-8.35070051" /energy="-16.3" /TU="U3090,U3091" /idTUdmin="U3091" /TUdmin="-174" /isTUend="FALSE" CDS complement(3878464..3879297) /gene="licT" /locus_tag="BSU_39080" /old_locus_tag="BSU39080" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:11447120, 11580842, 11733988, 12169607, 15699035, 21278164, 23475962, 28235843" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11447120, 11580842, 11733988, 12169607, 15699035, 21278164, 23475962, 28235843; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional antiterminator (BglG family)" /protein_id="NP_391787.2" /db_xref="EnsemblGenomes-Gn:BSU39080" /db_xref="EnsemblGenomes-Tr:CAB15944" /db_xref="GOA:P39805" /db_xref="InterPro:IPR001550" /db_xref="InterPro:IPR004341" /db_xref="InterPro:IPR011608" /db_xref="InterPro:IPR036634" /db_xref="InterPro:IPR036650" /db_xref="PDB:1H99" /db_xref="PDB:1L1C" /db_xref="PDB:1TLV" /db_xref="SubtiList:BG10474" /db_xref="UniProtKB/Swiss-Prot:P39805" /translation="MKIAKVINNNVISVVNEQGKELVVMGRGLAFQKKSGDDVDEARI EKVFTLDNKDVSEKFKTLLYDIPIECMEVSEEIISYAKLQLGKKLNDSIYVSLTDHIN FAIQRNQKGLDIKNALLWETKRLYKDEFAIGKEALVMVKNKTGVSLPEDEAGFIALHI VNAELNEEMPNIINITKVMQEILSIVKYHFKIEFNEESLHYYRFVTHLKFFAQRLFNG THMESQDDFLLDTVKEKYHRAYECTKKIQTYIEREYEHKLTSDELLYLTIHIERVVKQ A*" gene complement(3878464..3879297) /gene="licT" /locus_tag="BSU_39080" /old_locus_tag="BSU39080" promotor_-10 complement(3879328..3879347) /Source="Nicolas_upshift_promotors" /id="U3090" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.992007992007992" /psig=1 /xcortree=2725 /SigmaFactorBS="agtgaattgtactgaccagcttccgtctttccctgatgaTAT TGACCtagtacaaaaagaATGTACAATCAAGATATAGTctgttcttagtagatttgga g" /listShort="licT, S1507, bglS" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3879347) /Source="Nicolas_upshifts" /id="U3090" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.992007992007992" /psig=1 /xcortree=2725 /SigmaFactorBS="agtgaattgtactgaccagcttccgtctttccctgatgaTAT TGACCtagtacaaaaagaATGTACAATCAAGATATAGTctgttcttagtagatttgga g" /listShort="licT, S1507, bglS" /GFF_Attribute="listLong" promotor_-35 complement(3879361..3879368) /Source="Nicolas_upshift_promotors" /id="U3090" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.992007992007992" /psig=1 /xcortree=2725 /SigmaFactorBS="agtgaattgtactgaccagcttccgtctttccctgatgaTAT TGACCtagtacaaaaagaATGTACAATCAAGATATAGTctgttcttagtagatttgga g" /listShort="licT, S1507, bglS" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3879393..3880073) /gene="yxiP" /locus_tag="BSU_39090" /old_locus_tag="BSU39090" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type lp: lipoprotein" /codon_start=1 /transl_table=11 /product="putative lipoprotein" /protein_id="NP_391788.1" /db_xref="EnsemblGenomes-Gn:BSU39090" /db_xref="EnsemblGenomes-Tr:CAB15945" /db_xref="SubtiList:BG11145" /db_xref="UniProtKB/Swiss-Prot:P42307" /translation="MRRIGLCISLLVTVLVMSACESEGEAQMFADCDQKTVKQTAAKP MSSKKKQDFQALASDRQLAIVFSSMIQVSEAFDYGIGNPEYFVRISMTEEEADIAKEN LESIKLENKSLKKQNSEAVALLQKTRNQDMSRIEIQQLTENRAGFFETADSMIKLINQ VTPKNAKKTRQQLDQLKKQYTQYSAESIKIMNSIVKKQKADKASFERHLEALLQKQPG QQVRSELY*" gene complement(3879393..3880073) /gene="yxiP" /locus_tag="BSU_39090" /old_locus_tag="BSU39090" promotor_-10 complement(3880120..3880139) /Source="Nicolas_upshift_promotors" /id="U3091" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.54045954045954" /psig=1 /xcortree=2984 /SigmaFactorBS="gttttttcgcttcaaatcatacttttgatTTATTGCTggggt taggtgcaTCTGGTACCATTTAACTATAttttatggtattttccagaagggattcagc a" /listShort="yxiP, licT, S1507" /listLong="bglS" /label="promotor_-10" upshifts complement(3880129) /Source="Nicolas_upshifts" /id="U3091" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.54045954045954" /psig=1 /xcortree=2984 /SigmaFactorBS="gttttttcgcttcaaatcatacttttgatTTATTGCTggggt taggtgcaTCTGGTACCATTTAACTATAttttatggtattttccagaagggattcagc a" /listShort="yxiP, licT, S1507" /listLong="bglS" promotor_-35 complement(3880153..3880160) /Source="Nicolas_upshift_promotors" /id="U3091" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.54045954045954" /psig=1 /xcortree=2984 /SigmaFactorBS="gttttttcgcttcaaatcatacttttgatTTATTGCTggggt taggtgcaTCTGGTACCATTTAACTATAttttatggtattttccagaagggattcagc a" /listShort="yxiP, licT, S1507" /listLong="bglS" /label="promotor_-35" promotor_-35 3880221..3880224 /Source="Nicolas_upshift_promotors" /id="U3092" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.818181818181818" /psig="0.94005994005994" /xcortree=674 /SigmaFactorBS="agcgaaaaaacataaatattttgtaaaaattgacgtgcattc CATTcttttcaggcccatTTCTCGTACAATAGAAGTATcgttaccggagaggggctct g" /listShort="yxiO" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3880239..3880258 /Source="Nicolas_upshift_promotors" /id="U3092" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.818181818181818" /psig="0.94005994005994" /xcortree=674 /SigmaFactorBS="agcgaaaaaacataaatattttgtaaaaattgacgtgcattc CATTcttttcaggcccatTTCTCGTACAATAGAAGTATcgttaccggagaggggctct g" /listShort="yxiO" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3880239 /Source="Nicolas_upshifts" /id="U3092" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.818181818181818" /psig="0.94005994005994" /xcortree=674 /SigmaFactorBS="agcgaaaaaacataaatattttgtaaaaattgacgtgcattc CATTcttttcaggcccatTTCTCGTACAATAGAAGTATcgttaccggagaggggctct g" /listShort="yxiO" /GFF_Attribute="listLong" CDS 3880280..3881566 /gene="yxiO" /locus_tag="BSU_39100" /old_locus_tag="BSU39100" /function="16.1: Circulate" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 12583894, 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative efflux transporter" /protein_id="NP_391789.1" /db_xref="EnsemblGenomes-Gn:BSU39100" /db_xref="EnsemblGenomes-Tr:CAB15946" /db_xref="GOA:P42306" /db_xref="InterPro:IPR020846" /db_xref="InterPro:IPR024671" /db_xref="InterPro:IPR036259" /db_xref="SubtiList:BG11144" /db_xref="UniProtKB/Swiss-Prot:P42306" /translation="MMKRFTKQENSWVLYDWANSAYSIVVTTAVFPLFYKSAAAESGV SAAQSTAYLGYTIAISTFILAMLGPILGTIADYEGCKKKFFGFFVSAGVASTAMLAFI PSEHWLLLLLFYTVSAIGFSGANVFYDAFLVDVTPEKRMNLVSARGFGLGYIGSTIPF IISIAVILLAQAETIPVSVSAASQLSFFITAAWWGLFTIPMIKHVHQRYYIKKEPHIV INSFKRLGQTMKRIRQYRALFLFLLAYFFYIDGVGTIITMSTSYGSDLGIGSSSLLII LFVTQVVAAPFSIIYGKLAERFTGKTMLYVGIVIYMIVCVYAYFMETTLDFWILAMLV ATSQGGIQALSRSYFAKLVPKRHANEFFGFYNIFGKFASIMGPLLIAVTAQLTGKSST AVFSLIILFVIGIVILAFVPEETSTDVSQQQNDLPL*" gene 3880280..3881566 /gene="yxiO" /locus_tag="BSU_39100" /old_locus_tag="BSU39100" promotor_-10 complement(3881011..3881029) /Source="Nicolas_upshift_promotors" /id="U3093" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2817 /SigmaFactorBS="cctaaatctgatccataggatgtcgacatCGTAATAAtcgtg ccgactccGTCGATATAAAAGAAATAAgcgagcaagaagaggaaaagtgcccggtatt g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3881019) /Source="Nicolas_upshifts" /id="U3093" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2817 /SigmaFactorBS="cctaaatctgatccataggatgtcgacatCGTAATAAtcgtg ccgactccGTCGATATAAAAGAAATAAgcgagcaagaagaggaaaagtgcccggtatt g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(3881043..3881050) /Source="Nicolas_upshift_promotors" /id="U3093" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2817 /SigmaFactorBS="cctaaatctgatccataggatgtcgacatCGTAATAAtcgtg ccgactccGTCGATATAAAAGAAATAAgcgagcaagaagaggaaaagtgcccggtatt g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 3881537 /Source="Nicolas_upshifts" /id="D2036" /incds=0 /nref=1 /ntot=68 /MaxReadThrough="2.50578" /MaxDrop="3.06646" /score="-7.45683354" /energy="-16.7" /TU="NA" /idTUdmin="U3092" /TUdmin=0 /isTUend="TRUE" CDS complement(3881585..3883024) /gene="deaD" /locus_tag="BSU_39110" /old_locus_tag="BSU39110" /function="16.2: Construct biomass (Anabolism)" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:10481020, 16118224, 16611943, 17142894, 17229151, 17951299, 19839642, 20691700, 26755693" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10481020, 16118224, 16611943, 17142894, 17229151, 17951299, 19839642, 20691700, 26755693; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="ATP-dependent RNA helicase for 23S ribosomal RNAmaturation" /protein_id="NP_391790.2" /db_xref="EnsemblGenomes-Gn:BSU39110" /db_xref="EnsemblGenomes-Tr:CAB15947" /db_xref="GOA:P42305" /db_xref="InterPro:IPR000629" /db_xref="InterPro:IPR001650" /db_xref="InterPro:IPR005580" /db_xref="InterPro:IPR011545" /db_xref="InterPro:IPR014001" /db_xref="InterPro:IPR014014" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR028619" /db_xref="PDB:2G0C" /db_xref="PDB:2HJV" /db_xref="PDB:3MOJ" /db_xref="SubtiList:BG11143" /db_xref="UniProtKB/Swiss-Prot:P42305" /translation="MSHFKNYQISHDILRALEGLGYTEPTKVQQSVIPAALERKDLVV KSQTGSGKTASFGIPLCELANWDENKPQALILTPTRELAVQVKEDITNIGRFKRIKAT AVFGKSSFDKQKAELKQKSHIVVGTPGRVLDHIEKGTLPLDRLSYLVIDEADEMLNMG FIEQVEAIIKHLPTERTTMLFSATLPQDIEKLSRQYMQNPEHIEVKAAGLTTRNIEHA VIQVREENKFSLLKDVLMTENPDSCIIFCRTKEHVNQLTDELDDLGYPCDKIHGGMIQ EDRFDVMNEFKRGEYRYLVATDVAARGIDIENISLVINYDLPLEKESYVHRTGRTGRA GNKGKAISFVTAFEKRFLADIEEYIGFEIQKIEAPSQEEVARKKPEFLAKLNDRPESK KDKSEELNKDIMKLYFNGGKKKKIRAVDFVGTIAKIDGVSADDIGIITIMDNASYVEI LNGKGPHVLKVMKNTTVKGKQLKVNKANK*" gene complement(3881585..3883024) /gene="deaD" /locus_tag="BSU_39110" /old_locus_tag="BSU39110" downshifts complement(3881608) /Source="Nicolas_upshifts" /id="D2037" /incds=0 /nref=200 /ntot=269 /MaxReadThrough="1.50578" /MaxDrop="5.83238" /score="3.28924902" /energy="-18.2" /TU="NA" /idTUdmin="U3095" /TUdmin=5 /isTUend="TRUE" misc_feature complement(3883048..3883067) /Source="Nicolas_upshift_promotors" /id="U3094" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.496503496503497" /psig="0.56943056943057" /xcortree=1449 /SigmaFactorBS="agggaatcgctggcttttaatacatcatttttcgacaaaaca catatgccttggtcaaTTAGAGTATAATGAGAACATctgcaagagacaggagtttata c" /listShort="deaD" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(3883065) /Source="Nicolas_upshifts" /id="U3094" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.496503496503497" /psig="0.56943056943057" /xcortree=1449 /SigmaFactorBS="agggaatcgctggcttttaatacatcatttttcgacaaaaca catatgccttggtcaaTTAGAGTATAATGAGAACATctgcaagagacaggagtttata c" /listShort="deaD" /GFF_Attribute="listLong" CDS complement(3883106..3884254) /gene="yxiM" /locus_tag="BSU_39120" /old_locus_tag="BSU39120" /EC_number="3.1.-.-" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1c: Function from experimental evidences in the studied genus; PubMedId: 10746760, 25394512; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="esterase (lipoprotein)" /protein_id="NP_391791.2" /db_xref="EnsemblGenomes-Gn:BSU39120" /db_xref="EnsemblGenomes-Tr:CAB15948" /db_xref="GOA:P42304" /db_xref="InterPro:IPR008979" /db_xref="InterPro:IPR013830" /db_xref="InterPro:IPR036514" /db_xref="PDB:2O14" /db_xref="SubtiList:BG11142" /db_xref="UniProtKB/Swiss-Prot:P42304" /translation="MKKWMAAVFVMMLMLCFGGIENVKAAEPKVYQFDFGSGSMEPGY IGVRASDRYDRSKGYGFQTPENMRDVAASGAGVKSDAVQFLAYGTKSNNTFNVDLPNG LYEVKVTLGNTARASVAAEGVFQVINMTGDGAEDTFQIPVTDGQLNLLVTEGKAGTAF TLSALKIKKLSDQPVTNRTIYVGGDSTVCNYYPLNSSKQAGWGQMLPHYIDKHTFQVR NMASGGQIARGFRNDGQLEAILKYIKPGDYFMLQLGINDTNPKHKESEAEFKEVMRDM IRQVKAKGADVILSTPQGRATDFTSEGIHSSVNRWYRASILALAEEEKTYLIDLNVLS SAYFTSIGPERTLGLYMDGDTLHPNRAGADALARLAVQELKRQGIAGF*" gene complement(3883106..3884254) /gene="yxiM" /locus_tag="BSU_39120" /old_locus_tag="BSU39120" promotor_-10 complement(3884281..3884297) /Source="Nicolas_upshift_promotors" /id="U3095" /multdbtbs="-" /comp="M3" /sig="Sig-" /pcomp="0.466533466533467" /psig="0.466533466533467" /xcortree=812 /SigmaFactorBS="catttttattcctcaacgcaatttttttcttaattcagtcAT CATAaagaaacaatcaccGAGTATGCATTAATGTAttcgttttcatagagggggagtc t" /listShort="yxiM, deaD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3884297) /Source="Nicolas_upshifts" /id="U3095" /multdbtbs="-" /comp="M3" /sig="Sig-" /pcomp="0.466533466533467" /psig="0.466533466533467" /xcortree=812 /SigmaFactorBS="catttttattcctcaacgcaatttttttcttaattcagtcAT CATAaagaaacaatcaccGAGTATGCATTAATGTAttcgttttcatagagggggagtc t" /listShort="yxiM, deaD" /GFF_Attribute="listLong" S_feature complement(3884299..3884383) /Source="Nicolas_S_feature" /locus_tag="new_4018701_4018785_c" /HighExp="T3.30H, T4.0H, T2.30H, T3.0H, T2.0H, T-3.40H, T5.0H, T-2.40H, Lbexp, Oxctl" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1508" promotor_-35 complement(3884312..3884317) /Source="Nicolas_upshift_promotors" /id="U3095" /multdbtbs="-" /comp="M3" /sig="Sig-" /pcomp="0.466533466533467" /psig="0.466533466533467" /xcortree=812 /SigmaFactorBS="catttttattcctcaacgcaatttttttcttaattcagtcAT CATAaagaaacaatcaccGAGTATGCATTAATGTAttcgttttcatagagggggagtc t" /listShort="yxiM, deaD" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3884384..3884572) /gene="yxzI" /locus_tag="BSU_39129" /old_locus_tag="BSU39129" /function="18: Unknown function" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /pseudo /codon_start=1 /transl_table=11 /product="hypothetical protein" /db_xref="PSEUDO:CAX52710.1" /translation="MRFENISASKLDDLESIDSVALEIVPTDDQWERLRYYVYDEENQ ISFYCGGWDVIKCDKKSH*" gene complement(3884384..3884572) /gene="yxzI" /locus_tag="BSU_39129" /old_locus_tag="BSU39129" /pseudo CDS complement(3884603..3884734) /gene="yxzJ" /locus_tag="BSU_39139" /old_locus_tag="BSU39139" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="YP_003097796.1" /db_xref="EnsemblGenomes-Gn:BSU39139" /db_xref="EnsemblGenomes-Tr:CAX52711" /db_xref="UniProtKB/Swiss-Prot:C0H3T5" /translation="MNITQYEKLKQHLSDEDTGPFTLNEFSFYMKEDDRYIHIPVFE* " gene complement(3884603..3884734) /gene="yxzJ" /locus_tag="BSU_39139" /old_locus_tag="BSU39139" CDS complement(3884746..3885207) /gene="yxiK" /locus_tag="BSU_39140" /old_locus_tag="BSU39140" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; Product type f: factor" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_391793.1" /db_xref="EnsemblGenomes-Gn:BSU39140" /db_xref="EnsemblGenomes-Tr:CAB15950" /db_xref="SubtiList:BG11140" /db_xref="UniProtKB/Swiss-Prot:P42302" /translation="MEITSISSIGNLDMIELKPDQTVMACELEDAESFYRFWAGLAYD RIMIQVITTGSFIEDLSEYFEGHAYKVTKLAKREFHFQSILQEADRDIADFLFLLASI NDDVFLITDPQPDKSYFSEGKLQCLTDSGERIIWFEYDAVDIYMIGGESYK*" gene complement(3884746..3885207) /gene="yxiK" /locus_tag="BSU_39140" /old_locus_tag="BSU39140" CDS complement(3885223..3885519) /gene="yxiJ" /locus_tag="BSU_39150" /old_locus_tag="BSU39150" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_391794.1" /db_xref="EnsemblGenomes-Gn:BSU39150" /db_xref="EnsemblGenomes-Tr:CAB15951" /db_xref="InterPro:IPR025551" /db_xref="SubtiList:BG11139" /db_xref="UniProtKB/Swiss-Prot:P42320" /translation="MLQKLRKRQRELEEKQYPDELYGFEAEIYEFFMLVAGSLDYVLA NKRIPRHQRRSLEKSFFELYPDILPDMIKNDKDLYHHILLYEQVRQEICVALSN*" gene complement(3885223..3885519) /gene="yxiJ" /locus_tag="BSU_39150" /old_locus_tag="BSU39150" CDS complement(3885547..3886035) /gene="yxiI" /locus_tag="BSU_39160" /old_locus_tag="BSU39160" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_391795.1" /db_xref="EnsemblGenomes-Gn:BSU39160" /db_xref="EnsemblGenomes-Tr:CAB15952" /db_xref="InterPro:IPR020323" /db_xref="SubtiList:BG11138" /db_xref="UniProtKB/Swiss-Prot:P42301" /translation="MMNWRALSQTKQDRIWSEVNKIIKWKPGSRCHHIIPPDPYRVFD ISSAMSSKAGHNDVSGVLSDLETSILKAFQLGTGKNDVMYALDWQHDGYTFSPHQAMP KDEFGEWPVPVFPNGDYYFFFHQDFSWGLLGDPWKCAITVFGEELLEAIDNDPPILFR NK*" gene complement(3885547..3886035) /gene="yxiI" /locus_tag="BSU_39160" /old_locus_tag="BSU39160" CDS complement(3886053..3886505) /gene="yxzG" /locus_tag="BSU_39170" /old_locus_tag="BSU39170" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type f: factor" /codon_start=1 /transl_table=11 /product="putative nucleic acid binding protein" /protein_id="NP_391796.1" /db_xref="EnsemblGenomes-Gn:BSU39170" /db_xref="EnsemblGenomes-Tr:CAB15953" /db_xref="SubtiList:BG14170" /db_xref="UniProtKB/Swiss-Prot:O32285" /translation="MWCFTLDGQQKEIHIDRKLEEMDAPAVDDCYGLAEKNGLIYMLY YGDAVIAAFDETVVRRVWILSDKEPDSEAFDQLAISEEGFLVGTFNCYSADLKSSLYL ISADVSQEMEEITCCDSNGEGLDVQQLKLTSYAVYAVASSGVYKQDIQ*" gene complement(3886053..3886505) /gene="yxzG" /locus_tag="BSU_39170" /old_locus_tag="BSU39170" S_feature complement(3886506..3886574) /Source="Nicolas_S_feature" /locus_tag="new_4020908_4020976_c" /HighExp="T4.0H, T3.30H, T3.0H, T2.30H, T2.0H, T-3.40H, T5.0H, T-2.40H, T-4.40H, LBGexp" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.19384199999999999" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1509" CDS complement(3886575..3886904) /gene="yxiH" /locus_tag="BSU_39180" /old_locus_tag="BSU39180" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_391797.1" /db_xref="EnsemblGenomes-Gn:BSU39180" /db_xref="EnsemblGenomes-Tr:CAB15954" /db_xref="InterPro:IPR011042" /db_xref="SubtiList:BG11137" /db_xref="UniProtKB/Swiss-Prot:P42300" /translation="MKKLKLNKIINENTQDCFFHADPQGRVYIGKGLKGGITITIYDP SGDVRDFRVKEQISYSDILLFQQCADGYVFVYYESYEPKVKVFSEEGRVKSVFHLPSG VSCCLLD*" gene complement(3886575..3886904) /gene="yxiH" /locus_tag="BSU_39180" /old_locus_tag="BSU39180" S_feature complement(3886905..3887026) /Source="Nicolas_S_feature" /locus_tag="new_4021307_4021428_c" /HighExp="T3.30H, T4.0H, T3.0H, T2.30H, T-4.40H, T-3.40H, LBGexp, T-2.40H, T2.0H, T5.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1510" CDS complement(3887027..3887443) /gene="yxiG" /locus_tag="BSU_39190" /old_locus_tag="BSU39190" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_391798.1" /db_xref="EnsemblGenomes-Gn:BSU39190" /db_xref="EnsemblGenomes-Tr:CAB15955" /db_xref="SubtiList:BG11136" /db_xref="UniProtKB/Swiss-Prot:P42299" /translation="MTMYQTINEWVDYIDKGCSVLHLDFNVFKKELSLDIKVFEDEGE YTHKISFQNVASAYYSADVGDMRLEKIDPEEYNWQVFEMSYHPEGIGNLSNSIIPEYQ SNANFLIDMNRMLIAIEAETVRFDDQSFYAYQLNTK*" gene complement(3887027..3887443) /gene="yxiG" /locus_tag="BSU_39190" /old_locus_tag="BSU39190" CDS complement(3887494..3887862) /gene="yxzC" /locus_tag="BSU_39200" /old_locus_tag="BSU39200" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type f: factor" /codon_start=1 /transl_table=11 /product="putative nucleic acid binding protein" /protein_id="NP_391799.1" /db_xref="EnsemblGenomes-Gn:BSU39200" /db_xref="EnsemblGenomes-Tr:CAB15956" /db_xref="SubtiList:BG14167" /db_xref="UniProtKB/Swiss-Prot:O32286" /translation="MVDWKPFGTYLLRKKLQYLNISTVLCILIKNHLVLEYVVIKLSE TNLIECINKIKSVLNGQTTREEVSDWAGTYVYADDPEVEDDRVWDMLILLSGIDLKDS SETYLHSTDDLNDWIKQYTE*" gene complement(3887494..3887862) /gene="yxzC" /locus_tag="BSU_39200" /old_locus_tag="BSU39200" CDS complement(3887856..3888326) /gene="yxiF" /locus_tag="BSU_39210" /old_locus_tag="BSU39210" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_391800.1" /db_xref="EnsemblGenomes-Gn:BSU39210" /db_xref="EnsemblGenomes-Tr:CAB15957" /db_xref="SubtiList:BG11135" /db_xref="UniProtKB/Swiss-Prot:P42298" /translation="MQKRLIEKLAENKRRLLMSEIKEKLVPCAERGFTYRFADLAQSR QLLELVLSNSIPANTREVDALEKTEAKQLIWKISQSYVAYDDRDVLLFHQYSSEIGAL VCSFGKCLEHLDCLLECIEFDEGILNHSFILVEPKCQFGLCILHTEYGCELVYW*" gene complement(3887856..3888326) /gene="yxiF" /locus_tag="BSU_39210" /old_locus_tag="BSU39210" S_feature complement(3888327..3888651) /Source="Nicolas_S_feature" /locus_tag="new_4022729_4023053_c" /HighExp="T3.30H, T-2.40H, T2.30H, T3.0H, T4.0H, SMMPr, MG 120, C90, T2.0H, T-4.40H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1511" CDS complement(3888652..3889080) /gene="wapI" /locus_tag="BSU_39220" /old_locus_tag="BSU39220" /experiment="publication(s) with functional evidences, PMID:1529529, 16306698, 19763274, 23572593" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1529529, 16306698, 19763274, 23572593; Product type f: factor" /codon_start=1 /transl_table=11 /product="antitoxin of WapA tRNase" /protein_id="NP_391801.1" /db_xref="EnsemblGenomes-Gn:BSU39220" /db_xref="EnsemblGenomes-Tr:CAB15958" /db_xref="SubtiList:BG10798" /db_xref="UniProtKB/Swiss-Prot:Q07836" /translation="MAKIKDDCIELELTPRRYQELDDDPFILSVFELLENKKAVVRDF SAVLLESEYKVLISGIETMIKGNQDSISLETIEPFLFLSIDQENGNYRIKIKIIFDDY KESKSNSNLFEINCNEEKLESFVTALKLNLENTKNPSKLP*" gene complement(3888652..3889080) /gene="wapI" /locus_tag="BSU_39220" /old_locus_tag="BSU39220" CDS complement(3889142..3896146) /gene="wapA" /locus_tag="BSU_39230" /old_locus_tag="BSU39230" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:8316082, 9537385, 16306698, 16849803, 21636651, 23199363, 23572593, 23944997, 25666134, 28827522" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8316082, 9537385, 16306698, 16849803, 21636651, 23199363, 23572593, 23944997, 25666134, 28827522; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="cell wall-associated tRNA nuclease precursor; intercellular growth inhibitor" /protein_id="NP_391802.2" /db_xref="EnsemblGenomes-Gn:BSU39230" /db_xref="EnsemblGenomes-Tr:CAB15959" /db_xref="GOA:Q07833" /db_xref="InterPro:IPR006530" /db_xref="InterPro:IPR008979" /db_xref="InterPro:IPR013783" /db_xref="InterPro:IPR022385" /db_xref="InterPro:IPR031325" /db_xref="SubtiList:BG10797" /db_xref="UniProtKB/Swiss-Prot:Q07833" /translation="MKKRKRRNFKRFIAAFLVLALMISLVPADVLAKSTEEENGNRIA ADDPEETLQKEQTEEAVPFDPKDINKEGEITSERTENTKLYYEGDGVYKQEVYLDPIH TKETPDADWEDISPELKESTSKQVETENAILNSDFQKQMKNGLYATFEHNDHKVTYSL AEAKGPNKTSLTPKDTSADYKTDSNEIVYPDVFPNIDLQTFTFNENIKEDLVLHQYNG YNTFTFQLKTDLQAKEQEDGSIDFSDEKGKVVFSVPKPFMTDSKLDELSGEVERSDKV SYKLEKNEEGYLLHLTADENWLKDPERVYPVSIDPSTSLSVSSDTFVMSAYPTTNYSA SSQKWDANLKAYVLKTGYYDKTTGTNYAFMKFNNLKPIQNMTVTKATLKTYVAHSYYG TKATGLWLDTVNSNYDNAKVTWNTKPASKNIGKADVHKGQWASYDVTAAVKSWNSGGA NYGFKLHTNGNGKEYWKKLISSANSANKPYIEVTYTIPKGNTPTIKAYHNGDSTGYFD ISWKKVEGAKGYKVWIYNGKEYQAISAGNVTSWSTKGKKIWPTSAEIASKRYKLHLDG KDGAELALDPSPVYKNSGGSYATSKNYWIGVSAIFDQGEGAMSAPAKPVIPNVGKAQA PSAKGYNNGNATGYFDLSWKAVSGATGYKVQVFNGKGFETLDLGNQTSWTTKGKKIWP TSAEIKAGKYALHLKDGSGAELPINPGPTYKNAGGDGAKRNYSFKIIAYNKDGEAIAS PAATPALPDIARPKNVTGYLYTNTKSSQTGYVNLIWEKVQNAKGYKVNIYNGKEYQSF DVGDADHWTTQNKNIWPTSEEIKAGSYKLHTDGKGGELALDPSPVYNNANGNYKGKKN YSFTLVAYDANGETIPTAPFNPTFHEGAEFLGTEEYWSIIDIPSGQLNGATGNVIVNE EDLSIDGRGPGLGLSRTYNSLDSSDHLFGQGWYADAETSVISTDGGAMYIDEDATTHR FTKKADGTYQPPTGVYLELTETADQFILKTKDQTNAYFNKKGGKLQKVVDGHNNATVY TYNDKNQLTAITDASGRKLTFTYDENGHVTSITGPKNKKVTYSYENDLLKKVTDTDGT VTSYDYDSEGRLVKQYSANSTEAKPVFTEYQYSGHRLEKAINAKKETYVYSYDADKKT LLMTQPNGRKVQYGYNEAGNPIQVIDDAEGLKITTNTKYEGNNVVEDVDPNDVGTGKA TESYQYDKDGNVTSVKDAYGTETYEYNKNNDVTKMKDTEGNVTDIAYDGLDAVSETDQ SGKSSSAAVYDKYGNQIQSSKDLSASTNILKDGSFEAQKSGWNLTASKDSGKISVIAD KSGVLSGSKALEVLSQSTSAGTDHGYSSATQTVELEPNTTYTLSGKIKTDLAKSRAYF NIDLRDKDQKRIQWIHNEYSALAGKNDWTKRQITFTTPANAGKAVVYMEVDHKDKDGK GKAWFDEVQLEKGEVSSSYNPVQNSSFTSATENWNVSGASVDSEEGFNDDVSLKAART SASQAGSVTKQTVVLGQSANDKPVYLTLTGMSKASSVKFTDEKDYSLQANVTYADGST GIYNAKFPSGTQEWNRAAVVIPKTKPINKVDISILFQKSATGTVWFDDIRLIEGSLLT KSTYDSNGNYVTKEEDELGYATSTDYDETGKKTSETDAKGEKTTYTYDQADQLTNMTL SNGTSILHSYDKEGNEVSKTIRAGADQTYKFEYDVMGKLVKTTDPLGNVLASEYDANS NLTKTISPNGNEVSLSYDGTDRVKSKSYNGTEKYIFTYDKNGNETSVVNKEQNTTKKR TFDNKNRLTELTDRGGSQTWTYPSDSDKLKTFSWIHGDQKGTNQFTYNKLDQMIEMKD STSSYSFDYDENGNVQTFITGNGGGTSFSYDERNLVSSLHIGDKNGGDILTESYEYDA NGNRTTINSSASGKVQYEYGKLNQLVKETHEDGTVIEYTYDGFGNRKTVTTIKDGSSK TVNASFNIMNQLTKVNDESISYDKNGNRTSDGKFTYTWDAEDNLTAVTKKGEDKPFAT YKYDEKGNRIQKTVNGKVTNYFYDGDSLNVLYETDADNNVTKSYTYGDSGQLLSYTEN GKKYFYHYNAHGDIIAISDSTGKTVAKYQYDAWGNPTKTEASDEVKDNRYRYAGYQYD EETGLYYLMARYYEPRNGVFLSLDPDPGSDGDSLDQNGYAYGNNNPVMNVDPDGHWVW LVVNAGFAAYDGYKAYKSGKGWKGAAWAAASNFGPGKIFKGASRAYKFTKKAVKITGH TRHGLNQSIGRNGGRGVNLRAKLNAVRSPKKVIKQPNGATKYVGKKATVVLNKRGKVI TAYGSSRAKGSKHVFHTHGKGNKSKRRR*" gene complement(3889142..3896146) /gene="wapA" /locus_tag="BSU_39230" /old_locus_tag="BSU39230" misc_feature 3896153..3896167 /Source="Nicolas_upshift_promotors" /id="U3096" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.896103896103896" /psig="0.0919080919080919" /xcortree=301 /SigmaFactorBS="caatgaaccttttaaagtttcgcctctttctttttttcattt cctcTCTCCTTTTGTAATAaaagtaatatttactcaataatcttaactagactgaaat a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 3896167 /Source="Nicolas_upshifts" /id="U3096" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.896103896103896" /psig="0.0919080919080919" /xcortree=301 /SigmaFactorBS="caatgaaccttttaaagtttcgcctctttctttttttcattt cctcTCTCCTTTTGTAATAaaagtaatatttactcaataatcttaactagactgaaat a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 complement(3896177..3896196) /Source="Nicolas_upshift_promotors" /id="U3097" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.917082917082917" /psig=1 /xcortree=2783 /SigmaFactorBS="taatccttaaaataagataaattttctagaaaaaTATTGTAA tgatatttcagtctAGTTAAGATTATTGAGTAAAtattacttttattacaaaaggaga g" /listShort="wapA, yxxG, S1511, yxiF, yxzC, yxiG, S1510, yxiH, S1509, yxzG, yxiI, yxiJ, yxiK, yxzJ, yxzI, S1508, yxiM, deaD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3896192) /Source="Nicolas_upshifts" /id="U3097" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.917082917082917" /psig=1 /xcortree=2783 /SigmaFactorBS="taatccttaaaataagataaattttctagaaaaaTATTGTAA tgatatttcagtctAGTTAAGATTATTGAGTAAAtattacttttattacaaaaggaga g" /listShort="wapA, yxxG, S1511, yxiF, yxzC, yxiG, S1510, yxiH, S1509, yxzG, yxiI, yxiJ, yxiK, yxzJ, yxzI, S1508, yxiM, deaD" /GFF_Attribute="listLong" promotor_-35 complement(3896211..3896218) /Source="Nicolas_upshift_promotors" /id="U3097" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.917082917082917" /psig=1 /xcortree=2783 /SigmaFactorBS="taatccttaaaataagataaattttctagaaaaaTATTGTAA tgatatttcagtctAGTTAAGATTATTGAGTAAAtattacttttattacaaaaggaga g" /listShort="wapA, yxxG, S1511, yxiF, yxzC, yxiG, S1510, yxiH, S1509, yxzG, yxiI, yxiJ, yxiK, yxzJ, yxzI, S1508, yxiM, deaD" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3896308..3897243) /gene="yxxF" /locus_tag="BSU_39240" /old_locus_tag="BSU39240" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406, 22720735; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative transporter" /protein_id="NP_391803.1" /db_xref="EnsemblGenomes-Gn:BSU39240" /db_xref="EnsemblGenomes-Tr:CAB15960" /db_xref="GOA:Q07835" /db_xref="InterPro:IPR000620" /db_xref="SubtiList:BG10796" /db_xref="UniProtKB/Swiss-Prot:Q07835" /translation="MQQDPSISSKQKSTAVIKMVISMVIFGSIGFFSEHTNLPSFELV FVRCLCATLFLGFCWLASGQYKTEKWSKRDVLQTLACGFFLVFNWVFLFKSFEETSVT IAISVYHLAPVLVLLLGSFFYREKLNVISVSSIIICFLGTALISGINGSTSLTQLMGS GIIWAVLAALFYAFTTLLGKGIHNLSPYTTTFLQTGLGVIILIPFIHFGAFADLSQGN WIMVVSTGIIHTGIVYLLFFDSLRFLSTKFISIIVFLDPAVAIVLDTVFTGFRPDLYQ TLGIVMIFAGMALTLVRRQGKANVTAEGTDIEQIQ*" gene complement(3896308..3897243) /gene="yxxF" /locus_tag="BSU_39240" /old_locus_tag="BSU39240" downshifts complement(3896529) /Source="Nicolas_upshifts" /id="D2038" /incds=1 /nref=1 /ntot=153 /MaxReadThrough="1.33481" /MaxDrop="2.42407" /score="29.0290332" /energy="-5.9" /TU="NA" /idTUdmin="U3098" /TUdmin=22 /isTUend="TRUE" S_feature complement(3897244..3897364) /Source="Nicolas_S_feature" /locus_tag="new_4031646_4031766_c" /HighExp="T3.0H, T1.0H, T3.30H, LBGstat, T1.30H, T0.30H, T4.0H, M9-stat, T2.30H, T0.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.998" /TUlongSig="Sig-" /TUlongPSig="0.196" /label="S1512" CDS complement(3897395..3897841) /gene="yxiE" /locus_tag="BSU_39250" /old_locus_tag="BSU39250" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:10913081, 12644671, 17210127" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10913081, 12644671, 17210127; Product type f: factor" /codon_start=1 /transl_table=11 /product="phosphate starvation protein (universal stress protein A family)" /protein_id="NP_391804.1" /db_xref="EnsemblGenomes-Gn:BSU39250" /db_xref="EnsemblGenomes-Tr:CAB15961" /db_xref="GOA:P42297" /db_xref="InterPro:IPR006015" /db_xref="InterPro:IPR006016" /db_xref="InterPro:IPR014729" /db_xref="SubtiList:BG11134" /db_xref="UniProtKB/Swiss-Prot:P42297" /translation="MFNKMLVAIDGSDMSAKALDAAVHLAKEQQAELSILHVGREAVV TTSSLTGIVYVPEHFIDEIRNEVKKEGLKILENAKEKAAEKGVQAETIYANGEPAHEI LNHAKEKGVSLIVVGSRGISGLKEMMLGSVSHKVSQLSTCPVLIVR*" gene complement(3897395..3897841) /gene="yxiE" /locus_tag="BSU_39250" /old_locus_tag="BSU39250" downshifts complement(3897409) /Source="Nicolas_upshifts" /id="D2039" /incds=0 /nref=22 /ntot=144 /MaxReadThrough="4.33955" /MaxDrop="6.75522" /score="45.6082379" /energy="-8.4" /TU="U3098" /idTUdmin="U3099" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(3897878..3897897) /Source="Nicolas_upshift_promotors" /id="U3098" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.56943056943057" /psig="0.998001998001998" /xcortree=1609 /SigmaFactorBS="gacaattttttgaaaactcatgcgcttCAATTGACaataacg aaatgcAGGCGGACAATAAAAGAGAAagatgaaccacccacagtccgaaaggcgggaa g" /listShort="yxiE, S1512, yxxF" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3897885) /Source="Nicolas_upshifts" /id="U3098" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.56943056943057" /psig="0.998001998001998" /xcortree=1609 /SigmaFactorBS="gacaattttttgaaaactcatgcgcttCAATTGACaataacg aaatgcAGGCGGACAATAAAAGAGAAagatgaaccacccacagtccgaaaggcgggaa g" /listShort="yxiE, S1512, yxxF" /GFF_Attribute="listLong" promotor_-35 complement(3897911..3897918) /Source="Nicolas_upshift_promotors" /id="U3098" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.56943056943057" /psig="0.998001998001998" /xcortree=1609 /SigmaFactorBS="gacaattttttgaaaactcatgcgcttCAATTGACaataacg aaatgcAGGCGGACAATAAAAGAGAAagatgaaccacccacagtccgaaaggcgggaa g" /listShort="yxiE, S1512, yxxF" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3897944..3899353) /gene="bglH" /locus_tag="BSU_39260" /old_locus_tag="BSU39260" /EC_number="3.2.1.86" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:14652714, 15139916" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 14652714, 15139916; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="aryl-phospho-beta-d-glucosidase" /protein_id="NP_391805.2" /db_xref="EnsemblGenomes-Gn:BSU39260" /db_xref="EnsemblGenomes-Tr:CAB15962" /db_xref="GOA:P40740" /db_xref="InterPro:IPR001360" /db_xref="InterPro:IPR017853" /db_xref="InterPro:IPR018120" /db_xref="InterPro:IPR033132" /db_xref="SubtiList:BG10935" /db_xref="UniProtKB/Swiss-Prot:P40740" /translation="MSSNEKRFPEGFLWGGAVAANQVEGAYNEGGKGLSTADVSPNGI MSPFDESMTSLNLYHNGIDFYHRYKEDIALFAEMGFKAFRTSIAWTRIFPNGDEEEPN EEGLRFYDDLFDELLKHHIEPVVTISHYEMPLGLVKNYGGWKNRKVIEFYERYAKTVF KRYQHKVKYWMTFNEINVVLHAPFTGGGLVFEEGENKLNAMYQAAHHQFVASALAVKA GHDIIPDSKIGCMIAATTTYPMTSKPEDVFAAMENERKTLFFSDVQARGAYPGYMKRY LAENNIEIEMAEGDEELLKEHTVDYIGFSYYMSMAASTDPEELAKSGGNLLGGVKNPY LKSSEWGWQIDPKGLRITLNTLYDRYQKPLFIVENGLGAVDKVEEDGTIQDDYRINYL RDHLIEAREAIADGVELIGYTSWGPIDLVSASTAEMKKRYGFIYVDRDNEGNGTFNRI KKKSFNWYQQVIATNGESL*" gene complement(3897944..3899353) /gene="bglH" /locus_tag="BSU_39260" /old_locus_tag="BSU39260" CDS complement(3899376..3901205) /gene="bglP" /locus_tag="BSU_39270" /old_locus_tag="BSU39270" /EC_number="2.7.1.-" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:15849754, 16850406, 17074746, 8626332" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15849754, 16850406, 17074746, 8626332; Product type t: transporter" /codon_start=1 /transl_table=11 /product="phosphotransferase system (PTS) beta-glucoside-specific enzyme IIBCA component" /protein_id="NP_391806.2" /db_xref="EnsemblGenomes-Gn:BSU39270" /db_xref="EnsemblGenomes-Tr:CAB15963" /db_xref="GOA:P40739" /db_xref="InterPro:IPR001127" /db_xref="InterPro:IPR001996" /db_xref="InterPro:IPR003352" /db_xref="InterPro:IPR011055" /db_xref="InterPro:IPR011297" /db_xref="InterPro:IPR013013" /db_xref="InterPro:IPR018113" /db_xref="InterPro:IPR036878" /db_xref="SubtiList:BG10934" /db_xref="UniProtKB/Swiss-Prot:P40739" /translation="MDYDKLSKDILQLVGGEENVQRVIHCMTRLRFNLHDNAKADRSQ LEQLPGVMGTNISGEQFQIIIGNDVPKVYQAIVRHSNLSDEKSAGSSSQKKNVLSAVF DVISGVFTPILPAIAGAGMIKGLVALAVTFGWMAEKSQVHVILTAVGDGAFYFLPLLL AMSAARKFGSNPYVAAAIAAAILHPDLTALLGAGKPISFIGLPVTAATYSSTVIPILL SIWIASYVEKWIDRFTHASLKLIVVPTFTLLIVVPLTLITVGPLGAILGEYLSSGVNY LFDHAGLVAMILLAGTFSLIIMTGMHYAFVPIMINNIAQNGHDYLLPAMFLANMGQAG ASFAVFLRSRNKKFKSLALTTSITALMGITEPAMYGVNMRLKKPFAAALIGGAAGGAF YGMTGVASYIVGGNAGLPSIPVFIGPTFIYAMIGLVIAFAAGTAAAYLLGFEDVPSDG SQQPAVHEGSREIIHSPIKGEVKALSEVKDGVFSAGVMGKGFAIEPEEGEVVSPVRGS VTTIFKTKHAIGITSDQGAEILIHIGLDTVKLEGQWFTAHIKEGDKVAPGDPLVSFDL EQIKAAGYDVITPVIVTNTDQYSFSPVKEIGKVQPKEALLALS*" gene complement(3899376..3901205) /gene="bglP" /locus_tag="BSU_39270" /old_locus_tag="BSU39270" promotor_no_box complement(3901197..3901297) /Source="Nicolas_upshift_promotors" /id="U3099" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.362637362637363" /psig="0.195804195804196" /xcortree=1562 /SigmaFactorBS="ttaggaggtgatgcagcatttgatacaaaaaaagctggtgaa aggcggccacctttcatccagcagtccccccataaaaaggaggtatacacatggatta t" /listShort="bglP, bglH, yxiE" /listLong="S1512, yxxF" /label="promotor_no_box" upshifts complement(3901237) /Source="Nicolas_upshifts" /id="U3099" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.362637362637363" /psig="0.195804195804196" /xcortree=1562 /SigmaFactorBS="ttaggaggtgatgcagcatttgatacaaaaaaagctggtgaa aggcggccacctttcatccagcagtccccccataaaaaggaggtatacacatggatta t" /listShort="bglP, bglH, yxiE" /listLong="S1512, yxxF" S_feature complement(3901239..3901431) /Source="Nicolas_S_feature" /locus_tag="new_4035641_4035833_c" /HighExp="Diami, T0.30H, B60, T0.0H, G150, M9-stat, T1.0H, T1.30H, Gly, Oxctl" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.29980099999999998" /TUshortSig="SigA, SigA, SigA" /TUshortPSig="0.998, 0.994, 0.997" /TUlongSig="NA" /TUlongPSig="NA" /label="S1513" promotor_-10 complement(3901412..3901431) /Source="Nicolas_upshift_promotors" /id="U3100" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.688311688311688" /psig="0.998001998001998" /xcortree=1563 /SigmaFactorBS="cttttgttctagaaacgatagtcaacaccaaaaatgaaagCG TTGACAtctcacgaatctAGTGCTAAAGTATACCTACAaacaaataaaacgacccgtc a" /listShort="S1513, bglP, bglH, yxiE" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3901431) /Source="Nicolas_upshifts" /id="U3100" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.688311688311688" /psig="0.998001998001998" /xcortree=1563 /SigmaFactorBS="cttttgttctagaaacgatagtcaacaccaaaaatgaaagCG TTGACAtctcacgaatctAGTGCTAAAGTATACCTACAaacaaataaaacgacccgtc a" /listShort="S1513, bglP, bglH, yxiE" /GFF_Attribute="listLong" S_feature complement(3901433..3901566) /Source="Nicolas_S_feature" /locus_tag="new_4035835_4035968_c" /HighExp="S2, HiTm, Sw, S8, M9-stat, Lbstat, S0, T2.0H, Mal, S1" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="0.994, 0.997" /TUlongSig="NA" /TUlongPSig="NA" /label="S1514" promotor_-35 complement(3901444..3901451) /Source="Nicolas_upshift_promotors" /id="U3100" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.688311688311688" /psig="0.998001998001998" /xcortree=1563 /SigmaFactorBS="cttttgttctagaaacgatagtcaacaccaaaaatgaaagCG TTGACAtctcacgaatctAGTGCTAAAGTATACCTACAaacaaataaaacgacccgtc a" /listShort="S1513, bglP, bglH, yxiE" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3901588..3901896) /gene="yxxE" /locus_tag="BSU_39280" /old_locus_tag="BSU39280" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_391807.1" /db_xref="EnsemblGenomes-Gn:BSU39280" /db_xref="EnsemblGenomes-Tr:CAB15964" /db_xref="SubtiList:BG11071" /db_xref="UniProtKB/Swiss-Prot:P40738" /translation="MLLINKQKDPVFQFLAGTFHQDIETPDDAIQELLIEESKEYLED AIVFLTDFIESEHSDNKKNDYIQSCADGVYLPAFNLEPIDWLKNVIVQIKKSLKKFKR *" gene complement(3901588..3901896) /gene="yxxE" /locus_tag="BSU_39280" /old_locus_tag="BSU39280" downshifts complement(3901611) /Source="Nicolas_upshifts" /id="D2040" /incds=0 /nref=137 /ntot=221 /MaxReadThrough="3.99098" /MaxDrop="5.76651" /score="24.0715465" /energy="-21.3" /TU="U3101,U3102" /idTUdmin="U3101" /TUdmin="-3718" /isTUend="FALSE" CDS complement(3901942..3902385) /gene="rtbE" /locus_tag="BSU_39290" /old_locus_tag="BSU39290" /function="17: Mobile and extrachromosomal element functions" /experiment="publication(s) with functional evidences, PMID:22200572" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 22200572; Product type f: factor" /codon_start=1 /transl_table=11 /product="antitoxin factor of the RttD-RttE toxin-antitoxin system" /protein_id="NP_391808.1" /db_xref="EnsemblGenomes-Gn:BSU39290" /db_xref="EnsemblGenomes-Tr:CAB15965" /db_xref="InterPro:IPR018958" /db_xref="SubtiList:BG11070" /db_xref="UniProtKB/Swiss-Prot:P40737" /translation="MSYNFIKSNKENDFYPVNQSEIEEVEKNLNLKLPSELVNFYLEV GYGFIKGSEFNTNRILDPYSVRDFRLRINDFEFYPDIEIYDEFENDKLIFFEGSESAL MSIELNDNNKNPIYYYDIQIATSLTEFLRKIEENDQYYLDLLDDE*" gene complement(3901942..3902385) /gene="rtbE" /locus_tag="BSU_39290" /old_locus_tag="BSU39290" CDS complement(3902382..3904091) /gene="rtbD" /locus_tag="BSU_39300" /old_locus_tag="BSU39300" /function="17: Mobile and extrachromosomal element functions" /experiment="publication(s) with functional evidences, PMID:22200572" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 22200572; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="ribonuclease toxin of the RtbD-RtbE toxin-antitoxin system" /protein_id="NP_391809.2" /db_xref="EnsemblGenomes-Gn:BSU39300" /db_xref="EnsemblGenomes-Tr:CAB15966" /db_xref="GOA:P42296" /db_xref="InterPro:IPR003615" /db_xref="InterPro:IPR006829" /db_xref="InterPro:IPR027797" /db_xref="SubtiList:BG11133" /db_xref="UniProtKB/Swiss-Prot:P42296" /translation="MKTLDVHALHEGIQHTIEKLDKQKQQLEKLEKSVEHLAGMKDAL KGKGGDAIRTFYEECHKPFLLFFGIFIDEYKKVLKQTQHAISSVESNSHGMIAEAFLS HDARHGVKHAREVTEQLTDAVNRQTSAIDHIVSLPTVNDSFFRMETEQAERLISDTLN KLFQFDGQQTQALEAAKSDFQTMKKYIDQLETMYTGPKIEITGYKSGSILKSQEEENI NQIFGAINPQMKQADDSPMEMMLKKLAENEKSKVDSVVKTGDSKKVSKNIIVINGKVY NTSEHREHIKTDFSNAEVKQVVYNDTLYNVYISGNDMKLEPVVSLSDIKVDENGYVKI LETAVELTGVYDLFKAATGRDPVSGEKVTGKDRVVASINSVPFAKIAKLEKLIDINKL INNGKKAKKASEVKNVAKDKGKIANDVSGSANKINSDLIKKYARDIEQRTGRELPKNQ IDKLKEALRNKEYKKMSPIETAKHRTKFDKVKNKVIKEWEENTGQKWPVYKENVVSEK TGKIIRKKGDKYDAHHIIENTFGGEHEWWNMHPAKFPNEHQAGIHGTGSPANELFKGG KKK*" gene complement(3902382..3904091) /gene="rtbD" /locus_tag="BSU_39300" /old_locus_tag="BSU39300" misc_feature complement(3903253..3903272) /Source="Nicolas_upshift_promotors" /id="U3101" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.551448551448551" /psig="0.994005994005994" /xcortree=1873 /SigmaFactorBS="aacgggtgattctaaaaaggtaagtaaaaatatcatcgttat caatggtAAAGTGTATAATACGAGTGAacatagagaacatataaaaactgatttctca a" /listShort="yxxD, yxxE, S1514, S1513, bglP, bglH" /listLong="yxiE" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(3903261) /Source="Nicolas_upshifts" /id="U3101" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.551448551448551" /psig="0.994005994005994" /xcortree=1873 /SigmaFactorBS="aacgggtgattctaaaaaggtaagtaaaaatatcatcgttat caatggtAAAGTGTATAATACGAGTGAacatagagaacatataaaaactgatttctca a" /listShort="yxxD, yxxE, S1514, S1513, bglP, bglH" /listLong="yxiE" CDS complement(3904111..3904380) /gene="yxiC" /locus_tag="BSU_39310" /old_locus_tag="BSU39310" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_391810.1" /db_xref="EnsemblGenomes-Gn:BSU39310" /db_xref="EnsemblGenomes-Tr:CAB15967" /db_xref="InterPro:IPR020315" /db_xref="SubtiList:BG11132" /db_xref="UniProtKB/Swiss-Prot:P42295" /translation="MAQEIKMVYDTVKQGLSQLKNSAELKSSLPGHLSGRNHLNVVKS IEQLNKDIKELTEAYASVLAKHIAQTESAVNAMKETDENISSSMK*" gene complement(3904111..3904380) /gene="yxiC" /locus_tag="BSU_39310" /old_locus_tag="BSU39310" CDS complement(3904392..3904757) /gene="yxiB" /locus_tag="BSU_39320" /old_locus_tag="BSU39320" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_391811.1" /db_xref="EnsemblGenomes-Gn:BSU39320" /db_xref="EnsemblGenomes-Tr:CAB15968" /db_xref="InterPro:IPR031681" /db_xref="SubtiList:BG11131" /db_xref="UniProtKB/Swiss-Prot:P42294" /translation="MHSEMLLHSVKADLHEKQEQIHQLKRVLHEIRQIKHDFSEAQHL IHRPHLNREAWRGTHAERFEDIREGMNKAYQQIKSDQVSGIIESIEGKIHSLEGDVYS IRRQITRIEHEIEKEKHKK*" gene complement(3904392..3904757) /gene="yxiB" /locus_tag="BSU_39320" /old_locus_tag="BSU39320" S_feature complement(3904758..3904823) /Source="Nicolas_S_feature" /locus_tag="new_4039160_4039225_c" /HighExp="T-1.40H, T-3.40H, T2.30H, T-2.40H, T-0.40H, T1.0H, T-1.10H, T-5.40H, T3.30H, T1.30H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.997" /TUlongSig="NA" /TUlongPSig="NA" /label="S1515" promotor_-10 complement(3904810..3904829) /Source="Nicolas_upshift_promotors" /id="U3102" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.694305694305694" /psig="0.997002997002997" /xcortree=2983 /SigmaFactorBS="ccagttctatacctctcaagacaatcctttttacctATTTat ccaatatgacccATCATGTAATATGAAAATAGtctgtattgtaaagaatttacacagt t" /listShort="S1515, yxiB, yxiC, yxiD, yxxD, yxxE, S1514, S1513, bglP, bglH, yxiE" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3904823) /Source="Nicolas_upshifts" /id="U3102" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.694305694305694" /psig="0.997002997002997" /xcortree=2983 /SigmaFactorBS="ccagttctatacctctcaagacaatcctttttacctATTTat ccaatatgacccATCATGTAATATGAAAATAGtctgtattgtaaagaatttacacagt t" /listShort="S1515, yxiB, yxiC, yxiD, yxxD, yxxE, S1514, S1513, bglP, bglH, yxiE" /GFF_Attribute="listLong" promotor_-35 complement(3904844..3904847) /Source="Nicolas_upshift_promotors" /id="U3102" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.694305694305694" /psig="0.997002997002997" /xcortree=2983 /SigmaFactorBS="ccagttctatacctctcaagacaatcctttttacctATTTat ccaatatgacccATCATGTAATATGAAAATAGtctgtattgtaaagaatttacacagt t" /listShort="S1515, yxiB, yxiC, yxiD, yxxD, yxxE, S1514, S1513, bglP, bglH, yxiE" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3905064..3906473) /gene="abnB" /locus_tag="BSU_39330" /old_locus_tag="BSU39330" /EC_number="3.2.1.99" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:14973026, 18408032, 18607095, 20883454" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 14973026, 18408032, 18607095, 20883454; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="arabinan endo-1,5-alpha-L-arabinosidase ([Ca(2+)-dependent]" /protein_id="NP_391812.2" /db_xref="EnsemblGenomes-Gn:BSU39330" /db_xref="EnsemblGenomes-Tr:CAB15969" /db_xref="GOA:P42293" /db_xref="InterPro:IPR006710" /db_xref="InterPro:IPR023296" /db_xref="InterPro:IPR032291" /db_xref="PDB:2X8F" /db_xref="PDB:2X8S" /db_xref="PDB:2X8T" /db_xref="PDB:4COT" /db_xref="SubtiList:BG11130" /db_xref="UniProtKB/Swiss-Prot:P42293" /translation="MFNRLFRVCFLAALIMAFTLPNSVYAQKPIFKEVSVHDPSIIET NGTFYVFGSHLASAKSNDLMQWQQLTTSVSNDNPLIPNVYEELKETFEWAQSDTLWAA DVTQLADGKYYMYYNACRGDSPRSAMGVAVADNIEGPYKNKGIFLKSGMEGTSSDGTP YDATKHPNVVDPHTFFDKDGKLWMVYGSYSGGIFILEMNPKTGFPLPGQGYGKKLLGG NHSRIEGPYVLYNPDTQYYYLYLSYGGLDATGGYNIRVARSKKPDGPYYDAEGNPMLD VRGKGGTFFDDRSIEPYGVKLMGSYTFETENEKGTGYVSPGHNSAYYDEKTGRSYLIF HTRFPGRGEEHEVRVHQLFMNKDGWPVAAPYRYAGETLKEVKQKDITGTYKLIQHGKD ISADIKQTINIQLNKNHTISGEMTGTWRKTGKNTADITLAGKKYNGVFLRQWDSVREK NVMTFSVLNTSGEAVWGSK*" gene complement(3905064..3906473) /gene="abnB" /locus_tag="BSU_39330" /old_locus_tag="BSU39330" downshifts complement(3905087) /Source="Nicolas_upshifts" /id="D2041" /incds=0 /nref=2 /ntot=38 /MaxReadThrough="0.825980000000001" /MaxDrop="3.49689" /score="16.962389" /energy="-7.9" /TU="NA" /idTUdmin="U3101" /TUdmin="-7194" /isTUend="FALSE" S_feature complement(3906474..3906583) /Source="Nicolas_S_feature" /locus_tag="new_4040876_4040985_c" /HighExp="S2, T2.30H, BC, T2.0H, M9-stat, T3.0H, T3.30H, T4.0H, S1, T1.30H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="NA" /TUshortPSig="NA" /TUlongSig="NA" /TUlongPSig="NA" /label="S1516" CDS complement(3906607..3906771) /gene="yxzL" /locus_tag="BSU_39339" /old_locus_tag="BSU39339" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="YP_003097797.1" /db_xref="EnsemblGenomes-Gn:BSU39339" /db_xref="EnsemblGenomes-Tr:CAX52712" /db_xref="UniProtKB/Swiss-Prot:C0H3T6" /translation="MAVSQLMQNLTKQLLHVRERKTDVMQEGETAKELNYEGEDMQAT SSAQNRQTSV*" gene complement(3906607..3906771) /gene="yxzL" /locus_tag="BSU_39339" /old_locus_tag="BSU39339" promotor_-10 complement(3906656..3906674) /Source="Nicolas_upshift_promotors" /id="U3103" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.974025974025974" /psig="0.974025974025974" /xcortree=497 /SigmaFactorBS="tattacatgtacgcgaaagaaaaacagacgtgatgcaaGAAG GAGAAacagcaaaagAGTTGAACTATGAAGGAGAggatatgcaagcaacaagttctgc g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3906671) /Source="Nicolas_upshifts" /id="U3103" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.974025974025974" /psig="0.974025974025974" /xcortree=497 /SigmaFactorBS="tattacatgtacgcgaaagaaaaacagacgtgatgcaaGAAG GAGAAacagcaaaagAGTTGAACTATGAAGGAGAggatatgcaagcaacaagttctgc g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(3906685..3906693) /Source="Nicolas_upshift_promotors" /id="U3103" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.974025974025974" /psig="0.974025974025974" /xcortree=497 /SigmaFactorBS="tattacatgtacgcgaaagaaaaacagacgtgatgcaaGAAG GAGAAacagcaaaagAGTTGAACTATGAAGGAGAggatatgcaagcaacaagttctgc g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(3906963..3906982) /Source="Nicolas_upshift_promotors" /id="U3104" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.440559440559441" /psig=1 /xcortree=2012 /SigmaFactorBS="attaattggttcagcagcagaagtcaaaaggttttttTATAG TCTttaacaagttagATTGCTATTGTAATAGCGTGacgcagaaagcagaacaggtttt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3906979) /Source="Nicolas_upshifts" /id="U3104" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.440559440559441" /psig=1 /xcortree=2012 /SigmaFactorBS="attaattggttcagcagcagaagtcaaaaggttttttTATAG TCTttaacaagttagATTGCTATTGTAATAGCGTGacgcagaaagcagaacaggtttt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(3906995..3907002) /Source="Nicolas_upshift_promotors" /id="U3104" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.440559440559441" /psig=1 /xcortree=2012 /SigmaFactorBS="attaattggttcagcagcagaagtcaaaaggttttttTATAG TCTttaacaagttagATTGCTATTGTAATAGCGTGacgcagaaagcagaacaggtttt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 3907011..3907018 /Source="Nicolas_upshift_promotors" /id="U3105" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.586413586413586" /psig=1 /xcortree=495 /SigmaFactorBS="tagcaatctaacttgttaaagactataaaaaaaccTTTTGAC TtctgctgctgaaccAATTAATATAATACTCAGTTaatagttatcagaatttttagga a" /listShort="hutP, hutH, hutU, hutI, hutG, S1517, hutM" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3907033..3907052 /Source="Nicolas_upshift_promotors" /id="U3105" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.586413586413586" /psig=1 /xcortree=495 /SigmaFactorBS="tagcaatctaacttgttaaagactataaaaaaaccTTTTGAC TtctgctgctgaaccAATTAATATAATACTCAGTTaatagttatcagaatttttagga a" /listShort="hutP, hutH, hutU, hutI, hutG, S1517, hutM" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3907036 /Source="Nicolas_upshifts" /id="U3105" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.586413586413586" /psig=1 /xcortree=495 /SigmaFactorBS="tagcaatctaacttgttaaagactataaaaaaaccTTTTGAC TtctgctgctgaaccAATTAATATAATACTCAGTTaatagttatcagaatttttagga a" /listShort="hutP, hutH, hutU, hutI, hutG, S1517, hutM" /GFF_Attribute="listLong" CDS 3907090..3907536 /gene="hutP" /locus_tag="BSU_39340" /old_locus_tag="BSU39340" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:15758992, 16192572, 16427271, 17395359, 18445631, 23748184, 24650662" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15758992, 16192572, 16427271, 17395359, 18445631, 23748184, 24650662; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional antiterminator" /protein_id="NP_391813.2" /db_xref="EnsemblGenomes-Gn:BSU39340" /db_xref="EnsemblGenomes-Tr:CAB15970" /db_xref="GOA:P10943" /db_xref="InterPro:IPR015111" /db_xref="InterPro:IPR023552" /db_xref="InterPro:IPR036482" /db_xref="PDB:1VEA" /db_xref="PDB:1WMQ" /db_xref="PDB:1WPS" /db_xref="PDB:1WPT" /db_xref="PDB:1WPU" /db_xref="PDB:1WPV" /db_xref="PDB:1WRN" /db_xref="PDB:1WRO" /db_xref="PDB:1WRQ" /db_xref="PDB:3BOY" /db_xref="PDB:4H4L" /db_xref="SubtiList:BG10666" /db_xref="UniProtKB/Swiss-Prot:P10943" /translation="MTLHKERRIGRLSVLLLLNEAEESTQVEELERDGWKVCLGKVGS MDAHKVVAAIETASKKSGVIQSEGYRESHALYHATMEALHGVTRGEMLLGSLLRTVGL RFAVLRGNPYESEAEGDWIAVSLYGTIGAPIKGLEHETFGVGINHI*" gene 3907090..3907536 /gene="hutP" /locus_tag="BSU_39340" /old_locus_tag="BSU39340" downshifts 3907541 /Source="Nicolas_upshifts" /id="D2042" /incds=0 /nref=157 /ntot=226 /MaxReadThrough="6.10706" /MaxDrop="5.43744" /score="3.19376411" /energy="-17.8" /TU="U3105" /idTUdmin="U3105" /TUdmin="-7018" /isTUend="FALSE" CDS 3907649..3909175 /gene="hutH" /locus_tag="BSU_39350" /old_locus_tag="BSU39350" /EC_number="4.3.1.3" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 9535092, 10220322, 17395359; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="histidine ammonia-lyase (histidase)" /protein_id="NP_391814.1" /db_xref="EnsemblGenomes-Gn:BSU39350" /db_xref="EnsemblGenomes-Tr:CAB15971" /db_xref="GOA:P10944" /db_xref="InterPro:IPR001106" /db_xref="InterPro:IPR005921" /db_xref="InterPro:IPR008948" /db_xref="InterPro:IPR022313" /db_xref="InterPro:IPR024083" /db_xref="SubtiList:BG10667" /db_xref="UniProtKB/Swiss-Prot:P10944" /translation="MVTLDGSSLTTADVARVLFDFEEAAASEESMERVKKSRAAVERI VRDEKTIYGINTGFGKFSDVLIQKEDSAALQLNLILSHACGVGDPFPECVSRAMLLLR ANALLKGFSGVRAELIEQLLAFLNKRVHPVIPQQGSLGASGDLAPLSHLALALIGQGE VFFEGERMPAMTGLKKAGIQPVTLTSKEGLALINGTQAMTAMGVVAYIEAEKLAYQTE RIASLTIEGLQGIIDAFDEDIHLARGYQEQIDVAERIRFYLSDSGLTTSQGELRVQDA YSLRCIPQVHGATWQTLGYVKEKLEIEMNAATDNPLIFNDGDKVISGGNFHGQPIAFA MDFLKIAISELANIAERRIERLVNPQLNDLPPFLSPHPGLQSGAMIMQYAAASLVSEN KTLAHPASVDSIPSSANQEDHVSMGTIAARHAYQVIANTRRVIAIEAICALQAVEYRG IEHAASYTKQLFQEMRKVVPSIQQDRVFSYDIERLTDWLKKESLIPDHQNKELRGMNI *" gene 3907649..3909175 /gene="hutH" /locus_tag="BSU_39350" /old_locus_tag="BSU39350" CDS 3909172..3910830 /gene="hutU" /locus_tag="BSU_39360" /old_locus_tag="BSU39360" /EC_number="4.2.1.49" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 15313616, 17395359, 22933560; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="urocanase" /protein_id="NP_391815.1" /db_xref="EnsemblGenomes-Gn:BSU39360" /db_xref="EnsemblGenomes-Tr:CAB15972" /db_xref="GOA:P25503" /db_xref="InterPro:IPR023636" /db_xref="InterPro:IPR023637" /db_xref="InterPro:IPR035085" /db_xref="InterPro:IPR035400" /db_xref="InterPro:IPR035401" /db_xref="InterPro:IPR036190" /db_xref="PDB:2FKN" /db_xref="SubtiList:BG10668" /db_xref="UniProtKB/Swiss-Prot:P25503" /translation="MTDVKKSIRANRGTELECLGWEQEAVLRMLRNNLDPEVAEKPED LIVYGGIGKAARDWDAFHAIEHSLKTLKNDETLLVQSGKPVGMFRTHPQAPRVLLANS VLVPKWADWEHFHELEKKGLMMYGQMTAGSWIYIGSQGILQGTYETFAELARQHFGGS LKGTLTLTAGLGGMGGAQPLSVTMNEGVVIAVEVDEKRIDKRIETKYCDRKTASIEEA LAWAEEAKLAGKPLSIALLGNAAEVHHTLLNRGVKIDIVTDQTSAHDPLIGYVPEGYS LDEADRLRQDTPELYVRLAKQSMKKHVEAMLAFQQKGSIVFDYGNNIRQVAKDEGLEN AFDFPGFVPAYIRPLFCEGKGPFRWAALSGDPADIYRTDALLKELFPTNKALHRWIDM AQEKVTFQGLPSRICWLGYGERKKMGLAINELVRTGELKAPVVIGRDHLDCGSVASPN RETEAMKDGSDAVGDWAVLNALVNTAAGASWVSFHHGGGVGMGYSLHAGMVAVADGSE LADERLARVLTSDPGMGIIRHADAGYERAVEVAKEQDIIVPMQK*" gene 3909172..3910830 /gene="hutU" /locus_tag="BSU_39360" /old_locus_tag="BSU39360" CDS 3910843..3912108 /gene="hutI" /locus_tag="BSU_39370" /old_locus_tag="BSU39370" /EC_number="3.5.2.7" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:16990261, 17395359, 18296777" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16990261, 17395359, 18296777; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="imidazolone-5-propionate hydrolase" /protein_id="NP_391816.1" /db_xref="EnsemblGenomes-Gn:BSU39370" /db_xref="EnsemblGenomes-Tr:CAB15973" /db_xref="GOA:P42084" /db_xref="InterPro:IPR005920" /db_xref="InterPro:IPR006680" /db_xref="InterPro:IPR011059" /db_xref="InterPro:IPR032466" /db_xref="PDB:2BB0" /db_xref="PDB:2G3F" /db_xref="SubtiList:BG11100" /db_xref="UniProtKB/Swiss-Prot:P42084" /translation="MPKQIDTILINIGQLLTMESSGPRAGKSMQDLHVIEDAVVGIHE QKIVFAGQKGAEAGYEADEIIDCSGRLVTPGLVDPHTHLVFGGSREKEMNLKLQGISY LDILAQGGGILSTVKDTRAASEEELLQKAHFHLQRMLSYGTTTAEVKSGYGLEKETEL KQLRVAKKLHESQPVDLVSTFMGAHAIPPEYQNDPDDFLDQMLSLLPEIKEQELASFA DIFTETGVFTVSQSRRYLQKAAEAGFGLKIHADEIDPLGGAELAGKLKAVSADHLVGT SDEGIKKLAEAGTIAVLLPGTTFYLGKSTYARARAMIDEGVCVSLATDFNPGSSPTEN IQLIMSIAALHLKMTAEEIWHAVTVNAAYAIGKGEEAGQLKAGRSADLVIWQAPNYMY IPYHYGVNHVHQVMKNGTIVVNREGAILG*" gene 3910843..3912108 /gene="hutI" /locus_tag="BSU_39370" /old_locus_tag="BSU39370" CDS 3912101..3913060 /gene="hutG" /locus_tag="BSU_39380" /old_locus_tag="BSU39380" /EC_number="3.5.3.8" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2b: Function from indirect experimental evidences (e.g. phenotypes); PubMedId: 10931887, 15355972, 17395359; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="formiminoglutamate hydrolase" /protein_id="NP_391817.1" /db_xref="EnsemblGenomes-Gn:BSU39380" /db_xref="EnsemblGenomes-Tr:CAB15974" /db_xref="GOA:P42068" /db_xref="InterPro:IPR005923" /db_xref="InterPro:IPR006035" /db_xref="InterPro:IPR020855" /db_xref="InterPro:IPR023696" /db_xref="PDB:3M1R" /db_xref="SubtiList:BG11099" /db_xref="UniProtKB/Swiss-Prot:P42068" /translation="MDKYPFLREAGSSFKDRDVTKMSDLIATWDGQDIKGPALIGVPL SKSSISHSGASFAPGTIRQALKHSSAYSAELGEHVVSELLYDLGDIDIHVTDIVKSHH HIFQTMHALLSDHPDWVPLILGGDNSISYSTIKAIAQTKGTTAVIQFDAHHDVRNTED GGPTNGTPFRRLLDEEIIEGQHLIQLGIREFSNSQAYEAYAKKHNVNIHTMDMIREKG LIPTIKEILPVVQDKTDFIFISVDMDVLDQSHAPGCPAIGPGGLYTDELLEAVKYIAQ QPNVAGIEIVEVDPTLDFRDMTSRAAAHVLLHALKGMKLSPFK*" gene 3912101..3913060 /gene="hutG" /locus_tag="BSU_39380" /old_locus_tag="BSU39380" S_feature 3913061..3913135 /Source="Nicolas_S_feature" /locus_tag="new_4047463_4047537" /HighExp="Sw, BC, T3.30H, T4.0H, T5.0H, T3.0H, T2.30H, S8, M9-stat, T2.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1517" CDS 3913136..3914563 /gene="hutM" /locus_tag="BSU_39390" /old_locus_tag="BSU39390" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2b: Function from indirect experimental evidences (e.g. phenotypes); PubMedId: 7704263, 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="histidine degradation metabolites permease" /protein_id="NP_391818.2" /db_xref="EnsemblGenomes-Gn:BSU39390" /db_xref="EnsemblGenomes-Tr:CAB15975" /db_xref="GOA:P42087" /db_xref="InterPro:IPR002293" /db_xref="InterPro:IPR004840" /db_xref="InterPro:IPR004841" /db_xref="SubtiList:BG11101" /db_xref="UniProtKB/Swiss-Prot:P42087" /translation="MNLQENSSQQLKRTMKSRHLFMISLGGVIGTGLFLSTGYTLHQA GPGGTILAYVIGGLMMYLVMQCLGELSVAMPVTGSFQKYATTFIGPSTGFMVGIMYWI NWVVTVGSEFTASGILMQRWFPDSSVWMWSAIFAALLFICNAFSVKLFAETEFWFSSV KIVTIILFIILGGAAMFGLISLNGTADAPMLSNFTDHGGLFPNGFLAVFIAMISVSFA FSGTELIGVTAGESANPQKDIPRSIRNVAWRTVIFFIGAVFILSGLISWKDAGVIESP FVAVFAEIGIPYAADIMNFVILTALLSVANSGLYASTRMMWSLANENMISSRFKKVTS KGIPLNALMISMAVSCLSLVSSIVAPGTVYVVMVAIAGFAGVVVWMSIALSQLLFRKR FLKKGGDVKDLTFRTPLYPLMPIAALLLCSASCIGLAFDPNQRIALFCGVPCIILCYL IYHFKRNVTKAKKISQEEYPADHIL*" gene 3913136..3914563 /gene="hutM" /locus_tag="BSU_39390" /old_locus_tag="BSU39390" downshifts 3914559 /Source="Nicolas_upshifts" /id="D2043" /incds=0 /nref=11 /ntot=31 /MaxReadThrough="0.7432" /MaxDrop="6.18816" /score="8.21347356" /energy="-11.7" /TU="NA" /idTUdmin="U3105" /TUdmin=0 /isTUend="TRUE" CDS complement(3914607..3915908) /gene="pdp" /locus_tag="BSU_39400" /old_locus_tag="BSU39400" /EC_number="2.4.2.2" /EC_number="2.4.2.3" /EC_number="2.4.2.4" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:8550462, 10074062, 11065368, 15530033, 16469506, 21707079" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8550462, 10074062, 11065368, 15530033, 16469506, 21707079; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="pyrimidine-nucleoside phosphorylase" /protein_id="NP_391819.2" /db_xref="EnsemblGenomes-Gn:BSU39400" /db_xref="EnsemblGenomes-Tr:CAB15976" /db_xref="GOA:P39142" /db_xref="InterPro:IPR000053" /db_xref="InterPro:IPR000312" /db_xref="InterPro:IPR013102" /db_xref="InterPro:IPR017459" /db_xref="InterPro:IPR017872" /db_xref="InterPro:IPR018090" /db_xref="InterPro:IPR035902" /db_xref="InterPro:IPR036320" /db_xref="InterPro:IPR036566" /db_xref="PDB:5EP8" /db_xref="SubtiList:BG10985" /db_xref="UniProtKB/Swiss-Prot:P39142" /translation="MRMVDIIIKKQNGKELTTEEIQFFVNGYTDGSIPDYQASALAMA IFFQDMSDRERADLTMAMVNSGETIDLSAIEGIKVDKHSTGGVGDTTTLVLAPLVAAL DVPVAKMSGRGLGHTGGTIDKLEAIMGFHVELTKDEFIKLVNRDKVAVIGQSGNLTPA DKKLYALRDVTGTVNSIPLIASSIMSKKIAAGADAIVLDVKTGAGAFMKTEEDAAELA KAMVRIGNNVGRQTMAVISDMSQPLGFAIGNALEVKEAIDTLKGEGPEDLHELVLTLG SQMVVLAKKADTLDEARAKLEEVMKNGKALEKFKDFLKNQGGDSSIVDDPSKLPQAAY QIDVPAKEAGVVSEIVADEIGVAAMLLGAGRATKEDEIDLAVGIMLRKKVGDKVEKGE PLVTLYANRENVDEVIAKVYDNIRIAAEAKAPKLIHTLITE*" gene complement(3914607..3915908) /gene="pdp" /locus_tag="BSU_39400" /old_locus_tag="BSU39400" downshifts complement(3914624) /Source="Nicolas_upshifts" /id="D2044" /incds=0 /nref=122 /ntot=224 /MaxReadThrough="1.27022" /MaxDrop="5.60021" /score="14.0361257" /energy="-13.1" /TU="NA" /idTUdmin="U3107" /TUdmin="-11" /isTUend="TRUE" CDS complement(3915938..3917119) /gene="nupC" /locus_tag="BSU_39410" /old_locus_tag="BSU39410" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:8550462, 11065368, 12591866, 15849754, 16850406, 25890046" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8550462, 11065368, 12591866, 15849754, 16850406, 25890046; Product type t : transporter" /codon_start=1 /transl_table=11 /product="pyrimidine-nucleoside Na+(H+) cotransporter" /protein_id="NP_391820.2" /db_xref="EnsemblGenomes-Gn:BSU39410" /db_xref="EnsemblGenomes-Tr:CAB15977" /db_xref="GOA:P39141" /db_xref="InterPro:IPR002668" /db_xref="InterPro:IPR008276" /db_xref="InterPro:IPR011657" /db_xref="InterPro:IPR018270" /db_xref="SubtiList:BG10984" /db_xref="UniProtKB/Swiss-Prot:P39141" /translation="MKYLIGIIGLIVFLGLAWIASSGKKRIKIRPIVVMLILQFILGY ILLNTGIGNFLVGGFAKGFGYLLEYAAEGINFVFGGLVNADQTTFFMNVLLPIVFISA LIGILQKWKVLPFIIRYIGLALSKVNGMGRLESYNAVASAILGQSEVFISLKKELGLL NQQRLYTLCASAMSTVSMSIVGAYMTMLKPEYVVTALVLNLFGGFIIASIINPYEVAK EEDMLRVEEEEKQSFFEVLGEYILDGFKVAVVVAAMLIGFVAIIALINGIFNAVFGIS FQGILGYVFAPFAFLVGIPWNEAVNAGSIMATKMVSNEFVAMTSLTQNGFHFSGRTTA IVSVFLVSFANFSSIGIIAGAVKGLNEKQGNVVARFGLKLLYGATLVSFLSAAIVGLI Y*" gene complement(3915938..3917119) /gene="nupC" /locus_tag="BSU_39410" /old_locus_tag="BSU39410" S_feature complement(3917120..3917199) /Source="Nicolas_S_feature" /locus_tag="new_4051522_4051601_c" /HighExp="G150, G135, Oxctl, G180, Mt0, M40t45, Lbtran, M0t90, M40t90, S0" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="1, 0.996" /TUlongSig="NA" /TUlongPSig="NA" /label="S1518" CDS complement(3917200..3917871) /gene="deoC" /locus_tag="BSU_39420" /old_locus_tag="BSU39420" /EC_number="4.1.2.4" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:8550462, 10074062, 11065368, 27033207" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8550462, 10074062, 11065368, 27033207; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="deoxyribose-phosphate aldolase" /protein_id="NP_391821.2" /db_xref="EnsemblGenomes-Gn:BSU39420" /db_xref="EnsemblGenomes-Tr:CAB15978" /db_xref="GOA:P39121" /db_xref="InterPro:IPR002915" /db_xref="InterPro:IPR011343" /db_xref="InterPro:IPR013785" /db_xref="InterPro:IPR028581" /db_xref="SubtiList:BG10983" /db_xref="UniProtKB/Swiss-Prot:P39121" /translation="MSLANIIDHTALKPHTQKADILKLIEEAKTYKFASVCVNPTWVE LAAKELKGTGVDVCTVIGFPLGANTTETKAFETKDAISKGATEVDMVINIAALKDKED DVVEADIRGVVEAVAGKALVKVIIETCLLTDEEKERACRLAVSAGADFVKTSTGFSTG GATKEDIALMRKTVGPDIGVKASGGVRTKEDVDTMVEAGASRIGASAGVSIVKGENAS GGDNY*" gene complement(3917200..3917871) /gene="deoC" /locus_tag="BSU_39420" /old_locus_tag="BSU39420" promotor_-35 3917820..3917823 /Source="Nicolas_upshift_promotors" /id="U3106" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.343656343656344" /psig="0.972027972027972" /xcortree=1858 /SigmaFactorBS="tgtatgttttcgcttcttcaattagttttagaatgtccgctt TTTGtgtatgcggtttcaaAGCTGTATGATCAATTATGTtggctaatgacatccttcg c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 3917838 /Source="Nicolas_upshifts" /id="U3106" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.343656343656344" /psig="0.972027972027972" /xcortree=1858 /SigmaFactorBS="tgtatgttttcgcttcttcaattagttttagaatgtccgctt TTTGtgtatgcggtttcaaAGCTGTATGATCAATTATGTtggctaatgacatccttcg c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 3917839..3917858 /Source="Nicolas_upshift_promotors" /id="U3106" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.343656343656344" /psig="0.972027972027972" /xcortree=1858 /SigmaFactorBS="tgtatgttttcgcttcttcaattagttttagaatgtccgctt TTTGtgtatgcggtttcaaAGCTGTATGATCAATTATGTtggctaatgacatccttcg c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-10 complement(3917899..3917918) /Source="Nicolas_upshift_promotors" /id="U3107" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.625374625374625" /psig=1 /xcortree=1555 /SigmaFactorBS="cgttcaaacctttcattgaacaaaatttcaattacCAATTTA CatatgttcaaaagTCGGTTATGCTAAAAAATATcttaacaaaaaaggaagtgtgcga a" /listShort="deoC, S1518, nupC, pdp" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3917914) /Source="Nicolas_upshifts" /id="U3107" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.625374625374625" /psig=1 /xcortree=1555 /SigmaFactorBS="cgttcaaacctttcattgaacaaaatttcaattacCAATTTA CatatgttcaaaagTCGGTTATGCTAAAAAATATcttaacaaaaaaggaagtgtgcga a" /listShort="deoC, S1518, nupC, pdp" /GFF_Attribute="listLong" promotor_-35 complement(3917932..3917939) /Source="Nicolas_upshift_promotors" /id="U3107" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.625374625374625" /psig=1 /xcortree=1555 /SigmaFactorBS="cgttcaaacctttcattgaacaaaatttcaattacCAATTTA CatatgttcaaaagTCGGTTATGCTAAAAAATATcttaacaaaaaaggaagtgtgcga a" /listShort="deoC, S1518, nupC, pdp" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3917977..3918918) /gene="deoR" /locus_tag="BSU_39430" /old_locus_tag="BSU39430" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:8550462, 10074062, 10714997, 24863636" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8550462, 10074062, 10714997, 24863636; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator of pyrmidine deoxyribonucleosides degradation (DeoR-dR5P)" /protein_id="NP_391822.1" /db_xref="EnsemblGenomes-Gn:BSU39430" /db_xref="EnsemblGenomes-Tr:CAB15979" /db_xref="GOA:P39140" /db_xref="InterPro:IPR007324" /db_xref="InterPro:IPR013324" /db_xref="PDB:4OQP" /db_xref="PDB:4OQQ" /db_xref="SubtiList:BG10982" /db_xref="UniProtKB/Swiss-Prot:P39140" /translation="MDREKQQLSIEAARLYYQSDYSQQQIAEQLNISRPTVSRLLQYA KEKGYVQIRVMDPFEDLDALGSILEEKYGLLEAHVVFSPTPDYAGITHDLSRYGAEYM HETVKDGDIVGVSWGTTMYQIAQNMQPKQVKGVEVVQLKGGISHSRVNTYSAETIQLF AEAFQTMPRYLPLPVVFDNADVKRMVEKDRHIERIIEMGKQANIALFTVGTVRDEALL FRLGYFNEEEKALLKKQAVGDICSRFFDAKGNICSSAINDRTIGVELQDLRLKERSIL VAGGSRKVSSIHGALTGKYANVLIIDQHTARALVNDL*" gene complement(3917977..3918918) /gene="deoR" /locus_tag="BSU_39430" /old_locus_tag="BSU39430" promotor_-10 complement(3918963..3918982) /Source="Nicolas_upshift_promotors" /id="U3108" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.723276723276723" /psig="0.996003996003996" /xcortree=2323 /SigmaFactorBS="gagcgtttttcagtttcttagaaatcagGTGGatgaaagccg gcgccAGCCTGTATAATAAAAGCAAatcaaaagcagttttatcaggactgatccacag g" /listShort="deoR, deoC, S1518, nupC, pdp" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3918969) /Source="Nicolas_upshifts" /id="U3108" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.723276723276723" /psig="0.996003996003996" /xcortree=2323 /SigmaFactorBS="gagcgtttttcagtttcttagaaatcagGTGGatgaaagccg gcgccAGCCTGTATAATAAAAGCAAatcaaaagcagttttatcaggactgatccacag g" /listShort="deoR, deoC, S1518, nupC, pdp" /GFF_Attribute="listLong" S_feature complement(3918971..3919051) /Source="Nicolas_S_feature" /locus_tag="new_4053373_4053453_c" /HighExp="Etha, Diami, Salt, MG 10, Gly, MG 60, G180, GM 60, G135, dia5" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.55204399999999998" /TUshortSig="SigB" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S1519" promotor_-35 complement(3918998..3919001) /Source="Nicolas_upshift_promotors" /id="U3108" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.723276723276723" /psig="0.996003996003996" /xcortree=2323 /SigmaFactorBS="gagcgtttttcagtttcttagaaatcagGTGGatgaaagccg gcgccAGCCTGTATAATAAAAGCAAatcaaaagcagttttatcaggactgatccacag g" /listShort="deoR, deoC, S1518, nupC, pdp" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3919052..3919879) /gene="yxxB" /locus_tag="BSU_39440" /old_locus_tag="BSU39440" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 10746760, 15849754, 16850406; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative integral membrane protein" /protein_id="NP_391823.2" /db_xref="EnsemblGenomes-Gn:BSU39440" /db_xref="EnsemblGenomes-Tr:CAB15980" /db_xref="GOA:P39139" /db_xref="InterPro:IPR009597" /db_xref="SubtiList:BG10981" /db_xref="UniProtKB/Swiss-Prot:P39139" /translation="MAVKDRYMSKIKQETKPWIKRFGRLGYFAFGGVFILLGVLAFMT AAGAGRAKDSSGALQTLSRMPYGSLLLFFIGIGLIGYVIWMVLSAIKDTEGHGNSRRG LSRRIGNFFSAAVYTSIAWNALRFVFGQGDGGTSEQTWSAYVLAQPFGQWLTGLTGAG FIVFAIVQFMKGVRAAFMKEFDTSKMNKQMICITKNTGRAGNIARAIIFSAIGYFLIK TAMTADPDDTRGFDGALAELAQQPHGKLILSILALGLILYGMYAIMKGIYQHMTWEK* " gene complement(3919052..3919879) /gene="yxxB" /locus_tag="BSU_39440" /old_locus_tag="BSU39440" downshifts complement(3919851) /Source="Nicolas_upshifts" /id="D2045" /incds=0 /nref=6 /ntot=96 /MaxReadThrough="4.46865" /MaxDrop="3.48502" /score="14.6805498" /energy="-16" /TU="U3109,U3111" /idTUdmin="U3111" /TUdmin="-770" /isTUend="FALSE" promotor_-10 complement(3919904..3919922) /Source="Nicolas_upshift_promotors" /id="U3109" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=169 /SigmaFactorBS="aacgtatctcagccagccatagctgaggcaggagcTGTTTCA actttgttcaatcGGGAATGTTACAGTAAAGAtttctgtgaaagagggttggacacat g" /listShort="yxxB, S1519, deoR" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3919917) /Source="Nicolas_upshifts" /id="U3109" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=169 /SigmaFactorBS="aacgtatctcagccagccatagctgaggcaggagcTGTTTCA actttgttcaatcGGGAATGTTACAGTAAAGAtttctgtgaaagagggttggacacat g" /listShort="yxxB, S1519, deoR" /GFF_Attribute="listLong" promotor_-35 complement(3919936..3919942) /Source="Nicolas_upshift_promotors" /id="U3109" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=169 /SigmaFactorBS="aacgtatctcagccagccatagctgaggcaggagcTGTTTCA actttgttcaatcGGGAATGTTACAGTAAAGAtttctgtgaaagagggttggacacat g" /listShort="yxxB, S1519, deoR" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3919952..3921064) /gene="yxeR" /locus_tag="BSU_39450" /old_locus_tag="BSU39450" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 1860825, 10746760, 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative ethanolamine permease" /protein_id="NP_391824.1" /db_xref="EnsemblGenomes-Gn:BSU39450" /db_xref="EnsemblGenomes-Tr:CAB15981" /db_xref="GOA:P54957" /db_xref="InterPro:IPR007441" /db_xref="SubtiList:BG11894" /db_xref="UniProtKB/Swiss-Prot:P54957" /translation="MTVNDAVVFILAAFLLWGAADYCLGNRWGLGERFADGFKAMGPL ALSMIGIVSLAPVLAAILIPIVAPFYTAIGADPSSFANTILAIDMGGYALAGEMAKDP QAGLFSWVFLGTMMGPAIVFTIPVALGIIEKEDHPYFAKGILIGLCTVPIGCLIGGLC AGFDIGMIGKNLLIPSLLSAVIAFGLWRYTDRMIQLFHLFGKAVSMVAIIGLAAVSVE TMTGIVLIPGMENVETGIQTTGTIAIALAGAFPMTAFITKTFKKPLQALGKCLHLDET ATAGLVTSLAHHIPMLASLKDMTPRGKVINVAFAVSGAFVLGSHLGFVAGMKKEMAAA MIIGKLAGGVTAAAAAAWMTPAQSAKQQKRISASHS*" gene complement(3919952..3921064) /gene="yxeR" /locus_tag="BSU_39450" /old_locus_tag="BSU39450" CDS complement(3921134..3922471) /gene="yxeQ" /locus_tag="BSU_39460" /old_locus_tag="BSU39460" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 12193636, 16513748, 16885442; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative catabolic enzyme" /protein_id="NP_391825.2" /db_xref="EnsemblGenomes-Gn:BSU39460" /db_xref="EnsemblGenomes-Tr:CAB15982" /db_xref="GOA:P54956" /db_xref="InterPro:IPR005656" /db_xref="InterPro:IPR036148" /db_xref="SubtiList:BG11893" /db_xref="UniProtKB/Swiss-Prot:P54956" /translation="MSKQGLTAGLAEAVRTSQPEHSVDAIHEAKKGLLDFTAASFAGR EDKGIQKLLRLIEDEGGRPLVPVIGQGKKAAPLQSAMLNGFIAHALDFDDVHSDVRGH PSAVIVPALIASAARGHDERLLGAYVVGVEVMARLGESIGSRHYEKGWHNTGTLGAIA AACAVGYAEELTQEELEKAIGFAATQSAGMRVQFGTEMKPLHAGLAAQAGLLAVKLAQ SEFGGSRTALDGETGFFSLYGDVEKAQHTLLNDWGAPWRIVQPGLWFKIYPFCSAAHH AADAVRQLISEETISAANTERIEVIFPPGGDAALTERSPKAGEEGRFSVEYVIALALH GHGLTVEHFSSQPIPNGVQTTMGRIQRVYDNAIQPAPHAVPKGRFTIVRAYLSDGRIC EARVDCPKGAPGNELSEEDIIEKLTLTVPQEKARRIITAVEKADIKEFLAHIE*" gene complement(3921134..3922471) /gene="yxeQ" /locus_tag="BSU_39460" /old_locus_tag="BSU39460" CDS complement(3922468..3923610) /gene="sndB" /locus_tag="BSU_39470" /old_locus_tag="BSU39470" /EC_number="3.5.-.-" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:12193636, 16513748, 16885442, 23944997, 28032445" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12193636, 16513748, 16885442, 23944997, 28032445; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="N-acetyl-sulfur-metabolite deacetylase" /protein_id="NP_391826.2" /db_xref="EnsemblGenomes-Gn:BSU39470" /db_xref="EnsemblGenomes-Tr:CAB15983" /db_xref="GOA:P54955" /db_xref="InterPro:IPR002933" /db_xref="InterPro:IPR011650" /db_xref="InterPro:IPR017439" /db_xref="InterPro:IPR033846" /db_xref="InterPro:IPR036264" /db_xref="PDB:1YSJ" /db_xref="SubtiList:BG11892" /db_xref="UniProtKB/Swiss-Prot:P54955" /translation="MADKAFHTRLINMRRDLHEHPELSFQEVETTKKIRRWLEEEQIE ILDVPQLKTGVIAEIKGREDGPVIAIRADIDALPIQEQTNLPFASKVDGTMHACGHDF HTASIIGTAMLLNQRRAELKGTVRFIFQPAEEIAAGARKVLEAGVLNGVSAIFGMHNK PDLPVGTIGVKEGPLMASVDRFEIVIKGKGGHAGIPNNSIDPIAAAGQIISGLQSVVS RNISSLQNAVVSITRVQAGTSWNVIPDQAEMEGTVRTFQKEARQAVPEHMRRVAEGIA AGYGAQAEFKWFPYLPSVQNDGTFLNAASEAAARLGYQTVHAEQSPGGEDFALYQEKI PGFFVWMGTNGTEEWHHPAFTLDEEALTVASQYFAELAVIVLETIK*" gene complement(3922468..3923610) /gene="sndB" /locus_tag="BSU_39470" /old_locus_tag="BSU39470" CDS complement(3923627..3924376) /gene="yxeO" /locus_tag="BSU_39480" /old_locus_tag="BSU39480" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 12193636, 16513748, 16885442, 25875741; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative ABC transporter (ATP-binding protein)" /protein_id="NP_391827.1" /db_xref="EnsemblGenomes-Gn:BSU39480" /db_xref="EnsemblGenomes-Tr:CAB15984" /db_xref="GOA:P54954" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR017871" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR030679" /db_xref="SubtiList:BG11891" /db_xref="UniProtKB/Swiss-Prot:P54954" /translation="MITVKNIRKAFKDLVVLDGIDLEVKRGEVVAIIGPSGSGKSTLL RCLNLLERPDQGLIEIGEAKLNAEKFTRKEAHRLRQQTAMVFQNYNLFKNKTALQNIT EALIVAQHKPRDEAKRIGMEILKQVGLEHKADSYPITMSGGQQQRIGIARALAVNPHA ILLDEPTSALDPELVTGVLQVIKSIAEKQTTMIIVTHEMAFAKEVADQVIFMADGHII EQGTPEELFDHPKNERTKRFIKQVGEPAELI*" gene complement(3923627..3924376) /gene="yxeO" /locus_tag="BSU_39480" /old_locus_tag="BSU39480" CDS complement(3924389..3925063) /gene="yxeN" /locus_tag="BSU_39490" /old_locus_tag="BSU39490" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 12193636, 15849754, 16513748, 16850406, 16885442; Product type t : transporter" /codon_start=1 /transl_table=11 /product="putative ABC transporter (permease)" /protein_id="NP_391828.1" /db_xref="EnsemblGenomes-Gn:BSU39490" /db_xref="EnsemblGenomes-Tr:CAB15985" /db_xref="GOA:P54953" /db_xref="InterPro:IPR000515" /db_xref="InterPro:IPR010065" /db_xref="InterPro:IPR035906" /db_xref="SubtiList:BG11890" /db_xref="UniProtKB/Swiss-Prot:P54953" /translation="MNTIDWEFMISAFPTLIQALPITLFMAIAAMIFAIIGGLILALI TKNKIPVLHQLSKLYISFFRGVPTLVQLFLIYYGLPQLFPEMSKMTALTAAIIGLSLK NAAYLAEIFRAALNSVDDGQLEACLSVGMTKFQAYRRIILPQAIRNAIPATGNTFIGL LKETSLAFTLGVMEMFAQGKMYASGNLKYFETYLAVAIVYWVLTIIYSILQDLFERAM SKPYRT*" gene complement(3924389..3925063) /gene="yxeN" /locus_tag="BSU_39490" /old_locus_tag="BSU39490" CDS complement(3925086..3925880) /gene="yxeM" /locus_tag="BSU_39500" /old_locus_tag="BSU39500" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 12193636, 16513748, 16885442; Product type lp: lipoprotein" /codon_start=1 /transl_table=11 /product="putative ABC transporter (binding lipoprotein)" /protein_id="NP_391829.1" /db_xref="EnsemblGenomes-Gn:BSU39500" /db_xref="EnsemblGenomes-Tr:CAB15986" /db_xref="GOA:P54952" /db_xref="InterPro:IPR001638" /db_xref="InterPro:IPR018313" /db_xref="SubtiList:BG11889" /db_xref="UniProtKB/Swiss-Prot:P54952" /translation="MKMKKWTVLVVAALLAVLSACGNGNSSSKEDDNVLHVGATGQSY PFAYKENGKLTGFDVEVMEAVAKKIDMKLDWKLLEFSGLMGELQTGKLDTISNQVAVT DERKETYNFTKPYAYAGTQIVVKKDNTDIKSVDDLKGKTVAAVLGSNHAKNLESKDPD KKINIKTYETQEGTLKDVAYGRVDAYVNSRTVLIAQIKKTGLPLKLAGDPIVYEQVAF PFAKDDAHDKLRKKVNKALDELRKDGTLKKLSEKYFNEDITVEQKH*" gene complement(3925086..3925880) /gene="yxeM" /locus_tag="BSU_39500" /old_locus_tag="BSU39500" promotor_-35 3925452..3925461 /Source="Nicolas_upshift_promotors" /id="U3110" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp="0.99000999000999" /psig="0.99000999000999" /xcortree=1707 /SigmaFactorBS="gctttcaaggtttttcgcgtggtttgaaccgagaacggcTGC GACTGTCttgccttttaaaTCGTCTACTGATTTGAtgtctgtattgtcttttttgacg a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 3925473 /Source="Nicolas_upshifts" /id="U3110" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp="0.99000999000999" /psig="0.99000999000999" /xcortree=1707 /SigmaFactorBS="gctttcaaggtttttcgcgtggtttgaaccgagaacggcTGC GACTGTCttgccttttaaaTCGTCTACTGATTTGAtgtctgtattgtcttttttgacg a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 3925474..3925489 /Source="Nicolas_upshift_promotors" /id="U3110" /multdbtbs="-" /comp="M9" /sig="SigWXY" /pcomp="0.99000999000999" /psig="0.99000999000999" /xcortree=1707 /SigmaFactorBS="gctttcaaggtttttcgcgtggtttgaaccgagaacggcTGC GACTGTCttgccttttaaaTCGTCTACTGATTTGAtgtctgtattgtcttttttgacg a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" CDS complement(3925905..3926402) /gene="snaB" /locus_tag="BSU_39510" /old_locus_tag="BSU39510" /EC_number="2.3.1.-" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:12193636, 16513748, 16885442, 23944997, 28032445" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12193636, 16513748, 16885442, 23944997, 28032445; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="sulfur-containing aminoacid acetyltransferase" /protein_id="NP_391830.2" /db_xref="EnsemblGenomes-Gn:BSU39510" /db_xref="EnsemblGenomes-Tr:CAB15987" /db_xref="GOA:P54951" /db_xref="InterPro:IPR000182" /db_xref="InterPro:IPR016181" /db_xref="SubtiList:BG11888" /db_xref="UniProtKB/Swiss-Prot:P54951" /translation="MKPRYRLAVERDAEQLLELTLRAYEPIRKLGIRFAAAHADLDLV LKNIRENACYVMEEDGRIIATITLRMPWGKQPGPYGVPHIWWFAVDPDTGKKGIGTKL LQWLEETILRDTLKVPFVSLGTADKHPWLIEMYERKGYVRSGEQDLGKGHITVYMKKQ LRHDL*" gene complement(3925905..3926402) /gene="snaB" /locus_tag="BSU_39510" /old_locus_tag="BSU39510" CDS complement(3926416..3927741) /gene="yxeK" /locus_tag="BSU_39520" /old_locus_tag="BSU39520" /EC_number="1.14.-.-" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 8892809, 12193636, 15294834, 16513748, 16885442, 23944997; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="putative monooxygenase" /protein_id="NP_391831.1" /db_xref="EnsemblGenomes-Gn:BSU39520" /db_xref="EnsemblGenomes-Tr:CAB15988" /db_xref="GOA:P54950" /db_xref="InterPro:IPR011251" /db_xref="InterPro:IPR016215" /db_xref="InterPro:IPR036661" /db_xref="SubtiList:BG11887" /db_xref="UniProtKB/Swiss-Prot:P54950" /translation="MTSKKKQIKLGVFLAGTGHHVASWRHPDAPSDASMNLDYFKELA KTAERGKLDMLFLADSLSIDSKSHPNVLTRFEPFTLLSALAQVTSKIGLTATASTTYS EPFHIARQFASLDHLSNGRAGWNVVTSSIESTALNFSGEKHLEHHLRYQRAEEFVEIV KGLWDSWEEDAFIRNKETGEFFDKEKMHELNHKGEYFSVRGPLNVSRTPQGQPVIIQA GSSGDGKALAAKTAEVIFTAQNHLESAQEFYQSIKEQAAEFGRDPEKIAIMPGIFPII ADTEEAAQAKYKELQDLIIPSVGLQILQNYLGGIDLSAYPLDGPLPKLDAEASNAVKS RFKLVQEMAERDNMTIRELYKYVAGSRGHHIFVGTPEQLADKMQEWVDTKACDGFNIM PPLLPEGIEVFVDQVVPILQERGVFRKEYEGTTLREHFGLEKPVNRYAK*" gene complement(3926416..3927741) /gene="yxeK" /locus_tag="BSU_39520" /old_locus_tag="BSU39520" promotor_-10 complement(3927818..3927837) /Source="Nicolas_upshift_promotors" /id="U3111" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.64035964035964" /psig=1 /xcortree=1742 /SigmaFactorBS="aatagaaaaaattaatcttaactcATTGACAAacgtccaaga caaAGGTACATTTTGATTTATTCatattaaacgactaggaatataggagtttattttt c" /listShort="yxeK, yxeL, yxeM, yxeN, yxeO, yxeP, yxeQ, yxeR, yxxB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3927822) /Source="Nicolas_upshifts" /id="U3111" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.64035964035964" /psig=1 /xcortree=1742 /SigmaFactorBS="aatagaaaaaattaatcttaactcATTGACAAacgtccaaga caaAGGTACATTTTGATTTATTCatattaaacgactaggaatataggagtttattttt c" /listShort="yxeK, yxeL, yxeM, yxeN, yxeO, yxeP, yxeQ, yxeR, yxxB" /GFF_Attribute="listLong" promotor_-35 complement(3927851..3927858) /Source="Nicolas_upshift_promotors" /id="U3111" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.64035964035964" /psig=1 /xcortree=1742 /SigmaFactorBS="aatagaaaaaattaatcttaactcATTGACAAacgtccaaga caaAGGTACATTTTGATTTATTCatattaaacgactaggaatataggagtttattttt c" /listShort="yxeK, yxeL, yxeM, yxeN, yxeO, yxeP, yxeQ, yxeR, yxxB" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3927927..3928154) /gene="yxeJ" /locus_tag="BSU_39530" /old_locus_tag="BSU39530" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="NP_391832.2" /db_xref="EnsemblGenomes-Gn:BSU39530" /db_xref="EnsemblGenomes-Tr:CAB15989" /db_xref="SubtiList:BG11886" /db_xref="UniProtKB/Swiss-Prot:P54949" /translation="MSLINSHQSADSGLNIWSQLFFYTIVTASEWIGGLQKRRKGKGN GEILYEIIGRKLSLCFIRLSFLADIEVALVE*" gene complement(3927927..3928154) /gene="yxeJ" /locus_tag="BSU_39530" /old_locus_tag="BSU39530" CDS complement(3928141..3929127) /gene="yxeI" /locus_tag="BSU_39540" /old_locus_tag="BSU39540" /EC_number="3.5.1.11" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:15937167, 16511127, 18667582, 21978958" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15937167, 16511127, 18667582, 21978958; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="penicillin V amidase" /protein_id="NP_391833.2" /db_xref="EnsemblGenomes-Gn:BSU39540" /db_xref="EnsemblGenomes-Tr:CAB15990" /db_xref="GOA:P54948" /db_xref="InterPro:IPR029055" /db_xref="InterPro:IPR029132" /db_xref="PDB:2OQC" /db_xref="SubtiList:BG11885" /db_xref="UniProtKB/Swiss-Prot:P54948" /translation="MCTSLTLETADRKHVLARTMDFAFQLGTEVILYPRRYSWNSEAD GRAHQTQYAFIGMGRKLGNILFADGINESGLSCAALYFPGYAEYEKTIREDTVHIVPH EFVTWVLSVCQSLEDVKEKIRSLTIVEKKLDLLDTVLPLHWILSDRTGRNLTIEPRAD GLKVYDNQPGVMTNSPDFIWHVTNLQQYTGIRPKQLESKEMGGLALSAFGQGLGTVGL PGDYTPPSRFVRAVYLKEHLEPAADETKGVTAAFQILANMTIPKGAVITEEDEIHYTQ YTSVMCNETGNYYFHHYDNRQIQKVNLFHEDLDCLEPKVFSAKAEESIHELN*" gene complement(3928141..3929127) /gene="yxeI" /locus_tag="BSU_39540" /old_locus_tag="BSU39540" downshifts complement(3928145) /Source="Nicolas_upshifts" /id="D2046" /incds=0 /nref=7 /ntot=52 /MaxReadThrough="2.95669" /MaxDrop="3.32309" /score="23.0334771" /energy="-17.9" /TU="NA" /idTUdmin="U3113" /TUdmin=0 /isTUend="TRUE" promotor_-35 3928278..3928287 /Source="Nicolas_upshift_promotors" /id="U3112" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.98001998001998" /psig="0.98001998001998" /xcortree=1238 /SigmaFactorBS="agtggtggaaatagtagtttccagtttCGTTGCACATcacgg aagtatatTGCGTATAATGAATTTCGTCttcttccgttatcactgcgccctttggtat c" /listShort="S1520" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3928301..3928320 /Source="Nicolas_upshift_promotors" /id="U3112" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.98001998001998" /psig="0.98001998001998" /xcortree=1238 /SigmaFactorBS="agtggtggaaatagtagtttccagtttCGTTGCACATcacgg aagtatatTGCGTATAATGAATTTCGTCttcttccgttatcactgcgccctttggtat c" /listShort="S1520" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 3928311..3928944 /Source="Nicolas_S_feature" /locus_tag="new_4062713_4063346" /HighExp="S6, S7, S8, S5, Paraq, G150, H2O2, G180, LBGexp, Oxctl" /AntisenseName="yxeI" /AntisenseCor="0.24221971906572701" /AntisenseRegPval="-4.2" /CDS_PredictionProba="NA" /TUshortSig="SigK" /TUshortPSig="0.98" /TUlongSig="NA" /TUlongPSig="NA" /label="S1520" upshifts 3928311 /Source="Nicolas_upshifts" /id="U3112" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.98001998001998" /psig="0.98001998001998" /xcortree=1238 /SigmaFactorBS="agtggtggaaatagtagtttccagtttCGTTGCACATcacgg aagtatatTGCGTATAATGAATTTCGTCttcttccgttatcactgcgccctttggtat c" /listShort="S1520" /GFF_Attribute="listLong" promotor_-10 complement(3929182..3929201) /Source="Nicolas_upshift_promotors" /id="U3113" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.997002997002997" /psig="0.999000999001" /xcortree=629 /SigmaFactorBS="ttttttcgttttatttgatgtaatgtcaatTCTTTGACgaat cgatttgactTTCGTTATGCTGATAAAACCaattcgttcacaatatgtatgatattaa t" /listShort="yxeI" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3929193) /Source="Nicolas_upshifts" /id="U3113" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.997002997002997" /psig="0.999000999001" /xcortree=629 /SigmaFactorBS="ttttttcgttttatttgatgtaatgtcaatTCTTTGACgaat cgatttgactTTCGTTATGCTGATAAAACCaattcgttcacaatatgtatgatattaa t" /listShort="yxeI" /GFF_Attribute="listLong" promotor_-35 complement(3929216..3929223) /Source="Nicolas_upshift_promotors" /id="U3113" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.997002997002997" /psig="0.999000999001" /xcortree=629 /SigmaFactorBS="ttttttcgttttatttgatgtaatgtcaatTCTTTGACgaat cgatttgactTTCGTTATGCTGATAAAACCaattcgttcacaatatgtatgatattaa t" /listShort="yxeI" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3929282..3930094) /gene="hadM" /locus_tag="BSU_39550" /old_locus_tag="BSU39550" /EC_number="3.1.3.-" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 21575135, 23582330, 25527541, 25848029, 27435445; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="sugar-phosphate hydrolase (promiscuous)" /protein_id="NP_391834.1" /db_xref="EnsemblGenomes-Gn:BSU39550" /db_xref="EnsemblGenomes-Tr:CAB15991" /db_xref="GOA:P54947" /db_xref="InterPro:IPR000150" /db_xref="InterPro:IPR006379" /db_xref="InterPro:IPR023214" /db_xref="InterPro:IPR036412" /db_xref="SubtiList:BG11884" /db_xref="UniProtKB/Swiss-Prot:P54947" /translation="MYKLIAIDMDGTLLNDHHEVTEEVRDALHAAKAEGVKIVLCTGR PIGGVQRYLDELNLIEEGDYVIAYNGALVQNTHTNEVVSELSLGYDDLTSLYDLSLEL KTPMHFFDSSNLYTPNRDISEFTVYESYVTQVPLHFRKIDEVPKDILIPKVMFIDKPE NLSRVITSIPKDVREKYTMVRSAPFFYEILHSEASKGNAVRQLAQLLGIEQAEVMCIG DNGNDLTMIEWAGCGVAMANAIPEVLEAANFQTRSNNEHGVAHAIHELVLAK*" gene complement(3929282..3930094) /gene="hadM" /locus_tag="BSU_39550" /old_locus_tag="BSU39550" promotor_-10 complement(3930124..3930143) /Source="Nicolas_upshift_promotors" /id="U3114" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.853146853146853" /psig="0.998001998001998" /xcortree=2354 /SigmaFactorBS="aagggcggcgtctaaacagaatccggagaaaaccatctcttc CGGTTGAAtatcaaaaagaaaaAACGATATGATGGGACTATAgcctgaaaacgacatg a" /listShort="yxeH" /GFF_Attribute="listLong" /label="promotor_-10" CDS complement(3930134..3930691) /gene="yxeG" /locus_tag="BSU_39560" /old_locus_tag="BSU39560" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative integral inner membrane protein of unknown function" /protein_id="NP_391835.1" /db_xref="EnsemblGenomes-Gn:BSU39560" /db_xref="EnsemblGenomes-Tr:CAB15992" /db_xref="GOA:P54946" /db_xref="SubtiList:BG11883" /db_xref="UniProtKB/Swiss-Prot:P54946" /translation="MRNQKAERLVAAGLVLHIIQWIFILWAFLKVKHLFSDYTIYNPN VISGSMQSLSFIQMMRAMMYSGAIVNYVLFFALVLLIYGIVLHAILIVLEMAAYVMIR RNPSSSWGFFFIAAGVKLAILNITGIPFLAAGFLLMKQKKAENGVKAERKRKPRLRIR RQGRRLNRIRRKPSLPVEYQKEKTI*" gene complement(3930134..3930691) /gene="yxeG" /locus_tag="BSU_39560" /old_locus_tag="BSU39560" upshifts complement(3930147) /Source="Nicolas_upshifts" /id="U3114" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.853146853146853" /psig="0.998001998001998" /xcortree=2354 /SigmaFactorBS="aagggcggcgtctaaacagaatccggagaaaaccatctcttc CGGTTGAAtatcaaaaagaaaaAACGATATGATGGGACTATAgcctgaaaacgacatg a" /listShort="yxeH" /GFF_Attribute="listLong" promotor_-35 complement(3930158..3930165) /Source="Nicolas_upshift_promotors" /id="U3114" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.853146853146853" /psig="0.998001998001998" /xcortree=2354 /SigmaFactorBS="aagggcggcgtctaaacagaatccggagaaaaccatctcttc CGGTTGAAtatcaaaaagaaaaAACGATATGATGGGACTATAgcctgaaaacgacatg a" /listShort="yxeH" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3930672..3931106) /gene="yxeF" /locus_tag="BSU_39570" /old_locus_tag="BSU39570" /function="18: Unknown function" /experiment="publication(s) with functional evidences, PMID:11160890, 22693626" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11160890, 22693626; Product type s: structure" /codon_start=1 /transl_table=11 /product="lipocalin-like lipoprotein" /protein_id="NP_391836.1" /db_xref="EnsemblGenomes-Gn:BSU39570" /db_xref="EnsemblGenomes-Tr:CAB15993" /db_xref="InterPro:IPR012674" /db_xref="InterPro:IPR021664" /db_xref="PDB:2JOZ" /db_xref="SubtiList:BG11882" /db_xref="UniProtKB/Swiss-Prot:P54945" /translation="MVIPLRNKYGILFLIAVCIMVSGCQQQKEETPFYYGTWDEGRAP GPTDGVKSATVTFTEDEVVETEVMEGRGEVQLPFMAYKVISQSTDGSIEIQYLGPYYP LKSTLKRGENGTLIWEQNGQRKTMTRIESKTGREEKDEKSKS*" gene complement(3930672..3931106) /gene="yxeF" /locus_tag="BSU_39570" /old_locus_tag="BSU39570" promotor_-35 3931131..3931140 /Source="Nicolas_upshift_promotors" /id="U3115" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1295 /SigmaFactorBS="ctcaaggggatcaccattctttcctccttttttgggcgaatG CCGTGCCACtgtgccaatgacTACATAAGTTATAAGGAATTcacccacaaggagactg a" /listShort="yxeE" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 3931150 /Source="Nicolas_upshifts" /id="U3115" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1295 /SigmaFactorBS="ctcaaggggatcaccattctttcctccttttttgggcgaatG CCGTGCCACtgtgccaatgacTACATAAGTTATAAGGAATTcacccacaaggagactg a" /listShort="yxeE" /GFF_Attribute="listLong" promotor_-10 3931153..3931172 /Source="Nicolas_upshift_promotors" /id="U3115" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1295 /SigmaFactorBS="ctcaaggggatcaccattctttcctccttttttgggcgaatG CCGTGCCACtgtgccaatgacTACATAAGTTATAAGGAATTcacccacaaggagactg a" /listShort="yxeE" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3931166) /Source="Nicolas_upshifts" /id="U3116" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.995004995004995" /psig="0.004995004995005" /xcortree=689 /SigmaFactorBS="agctgagggctgtaatattgataagggTTCATgtgatcagTC TCCTTGTGGGTGAattccttataacttatgtagtcattggcacagtggcacggcattc g" /listShort="yxeF, yxeG, yxeH" /GFF_Attribute="listLong" S_feature complement(3931167..3931578) /Source="Nicolas_S_feature" /locus_tag="new_4065569_4065980_c" /HighExp="Salt, H2O2, Paraq, dia15, Oxctl, Diami, Cold, G150, Lbtran, LBGexp" /AntisenseName="yxeE" /AntisenseCor="-0.602938477548701" /AntisenseRegPval="-27.3" /CDS_PredictionProba="NA" /TUshortSig="Sig-, SigA" /TUshortPSig="0.391, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S1521" promotor_-10 complement(3931172..3931186) /Source="Nicolas_upshift_promotors" /id="U3116" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.995004995004995" /psig="0.004995004995005" /xcortree=689 /SigmaFactorBS="agctgagggctgtaatattgataagggTTCATgtgatcagTC TCCTTGTGGGTGAattccttataacttatgtagtcattggcacagtggcacggcattc g" /listShort="yxeF, yxeG, yxeH" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 complement(3931195..3931199) /Source="Nicolas_upshift_promotors" /id="U3116" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.995004995004995" /psig="0.004995004995005" /xcortree=689 /SigmaFactorBS="agctgagggctgtaatattgataagggTTCATgtgatcagTC TCCTTGTGGGTGAattccttataacttatgtagtcattggcacagtggcacggcattc g" /listShort="yxeF, yxeG, yxeH" /GFF_Attribute="listLong" /label="promotor_-35" CDS 3931195..3931560 /gene="cotNE" /locus_tag="BSU_39580" /old_locus_tag="BSU39580" /function="16.8: Protect" /function="16.13: Shape" /function="16.5: Explore" /experiment="publication(s) with functional evidences, PMID:10714992, 17905812, 19933362" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10714992, 17905812, 19933362; Product type s: structure" /codon_start=1 /transl_table=11 /product="inner spore coat protein" /protein_id="NP_391837.1" /db_xref="EnsemblGenomes-Gn:BSU39580" /db_xref="EnsemblGenomes-Tr:CAB15994" /db_xref="SubtiList:BG11881" /db_xref="UniProtKB/Swiss-Prot:P54944" /translation="MNPYQYYSPQLPQQEPYYSHYEYNPYPQQDVYDPYQMDRQPALE RRIAALERQNEQQSRELTRLTNEDRRQNREIARIAEQVNQLSQAVERHTRRLNRLNQR LRTVENRLNIPFTAGEGGF*" gene 3931195..3931560 /gene="cotNE" /locus_tag="BSU_39580" /old_locus_tag="BSU39580" downshifts 3931574 /Source="Nicolas_upshifts" /id="D2047" /incds=0 /nref=31 /ntot=47 /MaxReadThrough="1.46494" /MaxDrop="8.36553" /score="27.2157513" /energy="-12.2" /TU="U3115" /idTUdmin="U3115" /TUdmin="-38" /isTUend="FALSE" promotor_-10 complement(3931578..3931582) /Source="Nicolas_upshift_promotors" /id="U3117" /multdbtbs="-" /comp="M9" /sig="Sig-" /pcomp="0.390609390609391" /psig="0.390609390609391" /xcortree=290 /SigmaFactorBS="cgttttaacatataagaaatgcggaaaacgaaaccCtgagat gggagaatcgtattCCGCTttttttctttgtttcgctcagaaaccgccttcccctgca g" /listShort="S1521" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3931578) /Source="Nicolas_upshifts" /id="U3117" /multdbtbs="-" /comp="M9" /sig="Sig-" /pcomp="0.390609390609391" /psig="0.390609390609391" /xcortree=290 /SigmaFactorBS="cgttttaacatataagaaatgcggaaaacgaaaccCtgagat gggagaatcgtattCCGCTttttttctttgtttcgctcagaaaccgccttcccctgca g" /listShort="S1521" /GFF_Attribute="listLong" S_feature complement(3931580..3931666) /Source="Nicolas_S_feature" /locus_tag="new_4065982_4066068_c" /HighExp="Salt, S8, H2O2, dia15, S7, Paraq, Diami, aero, Oxctl, Cold" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1522" promotor_-35 complement(3931603) /Source="Nicolas_upshift_promotors" /id="U3117" /multdbtbs="-" /comp="M9" /sig="Sig-" /pcomp="0.390609390609391" /psig="0.390609390609391" /xcortree=290 /SigmaFactorBS="cgttttaacatataagaaatgcggaaaacgaaaccCtgagat gggagaatcgtattCCGCTttttttctttgtttcgctcagaaaccgccttcccctgca g" /listShort="S1521" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(3931659..3931678) /Source="Nicolas_upshift_promotors" /id="U3118" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.74925074925075" /psig=1 /xcortree=2444 /SigmaFactorBS="ctacaattattttcctcagcccctctaTCTTTGAAtgaaaac ggtaaaGATTGTATACTGGGTACAAAccctttttatgtaaatgttccgttttaacata t" /listShort="S1522, S1521, yxeF, yxeG, yxeH" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3931666) /Source="Nicolas_upshifts" /id="U3118" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.74925074925075" /psig=1 /xcortree=2444 /SigmaFactorBS="ctacaattattttcctcagcccctctaTCTTTGAAtgaaaac ggtaaaGATTGTATACTGGGTACAAAccctttttatgtaaatgttccgttttaacata t" /listShort="S1522, S1521, yxeF, yxeG, yxeH" /GFF_Attribute="listLong" promotor_-35 complement(3931692..3931699) /Source="Nicolas_upshift_promotors" /id="U3118" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.74925074925075" /psig=1 /xcortree=2444 /SigmaFactorBS="ctacaattattttcctcagcccctctaTCTTTGAAtgaaaac ggtaaaGATTGTATACTGGGTACAAAccctttttatgtaaatgttccgttttaacata t" /listShort="S1522, S1521, yxeF, yxeG, yxeH" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 3931739..3931745 /Source="Nicolas_upshift_promotors" /id="U3119" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp="0.97002997002997" /psig="0.97002997002997" /xcortree=861 /SigmaFactorBS="ggctgaggaaaataattgtagttcctctttgacGGAATTTct tttcattcaagTTGCATGATAATaccgactcacgtcaatcgatacatggagggatcat t" /listShort="yxeD" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3931759..3931770 /Source="Nicolas_upshift_promotors" /id="U3119" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp="0.97002997002997" /psig="0.97002997002997" /xcortree=861 /SigmaFactorBS="ggctgaggaaaataattgtagttcctctttgacGGAATTTct tttcattcaagTTGCATGATAATaccgactcacgtcaatcgatacatggagggatcat t" /listShort="yxeD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3931766 /Source="Nicolas_upshifts" /id="U3119" /multdbtbs="SigG" /comp="M8" /sig="SigGF" /pcomp="0.97002997002997" /psig="0.97002997002997" /xcortree=861 /SigmaFactorBS="ggctgaggaaaataattgtagttcctctttgacGGAATTTct tttcattcaagTTGCATGATAATaccgactcacgtcaatcgatacatggagggatcat t" /listShort="yxeD" /GFF_Attribute="listLong" CDS 3931808..3932161 /gene="yxeD" /locus_tag="BSU_39590" /old_locus_tag="BSU39590" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 26506528" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_391838.2" /db_xref="EnsemblGenomes-Gn:BSU39590" /db_xref="EnsemblGenomes-Tr:CAB15995" /db_xref="SubtiList:BG11880" /db_xref="UniProtKB/Swiss-Prot:P54943" /translation="MHNTQHGLQQLNQCRQTAQQLIQQTQQSSQQYRQMLHQEQQNIQ MLQQILNHEQQAAHTIQQALHGHDMAIQKCQQVVNMCNQMQQELTGQSSVMNTNVSTL PFGQNTTFQQQSYQQ*" gene 3931808..3932161 /gene="yxeD" /locus_tag="BSU_39590" /old_locus_tag="BSU39590" downshifts 3932156 /Source="Nicolas_upshifts" /id="D2048" /incds=0 /nref=24 /ntot=55 /MaxReadThrough="0.20641" /MaxDrop="6.88486" /score="27.2157513" /energy="-12.2" /TU="NA" /idTUdmin="U3119" /TUdmin="-6" /isTUend="TRUE" CDS complement(3932205..3932603) /gene="yxeC" /locus_tag="BSU_39600" /old_locus_tag="BSU39600" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative integral membrane protein of unknown function" /protein_id="NP_391839.2" /db_xref="EnsemblGenomes-Gn:BSU39600" /db_xref="EnsemblGenomes-Tr:CAB15996" /db_xref="GOA:P54942" /db_xref="SubtiList:BG11879" /db_xref="UniProtKB/Swiss-Prot:P54942" /translation="MGITKRGAAWEWLHSWWMLFIFMPFAITSFFAFLFIGIKVRNRK WIMYGIIYFFIFAFGFVLPDLPGVFIVVPLWAVTIIHGFKVRPLYLIQLDVYKDHVEA RAFAEARSEAESRFHAPKQSIQDIHIRKEQ*" gene complement(3932205..3932603) /gene="yxeC" /locus_tag="BSU_39600" /old_locus_tag="BSU39600" downshifts complement(3932213) /Source="Nicolas_upshifts" /id="D2049" /incds=0 /nref=145 /ntot=243 /MaxReadThrough="1.70512" /MaxDrop="5.26494" /score="9.81431167" /energy="-12.2" /TU="NA" /idTUdmin="U3120" /TUdmin=3 /isTUend="TRUE" promotor_-10 complement(3932618..3932637) /Source="Nicolas_upshift_promotors" /id="U3120" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.602397602397602" /psig="0.999000999001" /xcortree=2316 /SigmaFactorBS="tatcactatttttaagggagaaagtttttcccgtttatgGGT GacgcggtgtgcctaATCGATTATTATAGGTAAATaggaggagaaaaatatgggaatt a" /listShort="yxeC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3932634) /Source="Nicolas_upshifts" /id="U3120" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.602397602397602" /psig="0.999000999001" /xcortree=2316 /SigmaFactorBS="tatcactatttttaagggagaaagtttttcccgtttatgGGT GacgcggtgtgcctaATCGATTATTATAGGTAAATaggaggagaaaaatatgggaatt a" /listShort="yxeC" /GFF_Attribute="listLong" promotor_-35 complement(3932652..3932655) /Source="Nicolas_upshift_promotors" /id="U3120" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.602397602397602" /psig="0.999000999001" /xcortree=2316 /SigmaFactorBS="tatcactatttttaagggagaaagtttttcccgtttatgGGT GacgcggtgtgcctaATCGATTATTATAGGTAAATaggaggagaaaaatatgggaatt a" /listShort="yxeC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 3932691..3932698 /Source="Nicolas_upshift_promotors" /id="U3121" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.585414585414585" /psig=1 /xcortree=2105 /SigmaFactorBS="cgggaaaaactttctcccttaaaaatagtGATAGACGgagaa caggtttctTGCTATATTATTAATTGATAatgataatcattactaatctattgagata c" /listShort="yxeB, S1523" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(3932707..3932725) /Source="Nicolas_upshift_promotors" /id="U3122" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.96903096903097" /psig="0.96903096903097" /xcortree=775 /SigmaFactorBS="atcaagaaccctcccactatgtatctcaatagattaGTAATG attatcattatcaatTAATAATATAGCAAGAAACctgttctccgtctatcactatttt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-10 3932713..3932732 /Source="Nicolas_upshift_promotors" /id="U3121" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.585414585414585" /psig=1 /xcortree=2105 /SigmaFactorBS="cgggaaaaactttctcccttaaaaatagtGATAGACGgagaa caggtttctTGCTATATTATTAATTGATAatgataatcattactaatctattgagata c" /listShort="yxeB, S1523" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3932722 /Source="Nicolas_upshifts" /id="U3121" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.585414585414585" /psig=1 /xcortree=2105 /SigmaFactorBS="cgggaaaaactttctcccttaaaaatagtGATAGACGgagaa caggtttctTGCTATATTATTAATTGATAatgataatcattactaatctattgagata c" /listShort="yxeB, S1523" /GFF_Attribute="listLong" upshifts complement(3932722) /Source="Nicolas_upshifts" /id="U3122" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.96903096903097" /psig="0.96903096903097" /xcortree=775 /SigmaFactorBS="atcaagaaccctcccactatgtatctcaatagattaGTAATG attatcattatcaatTAATAATATAGCAAGAAACctgttctccgtctatcactatttt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(3932741..3932746) /Source="Nicolas_upshift_promotors" /id="U3122" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.96903096903097" /psig="0.96903096903097" /xcortree=775 /SigmaFactorBS="atcaagaaccctcccactatgtatctcaatagattaGTAATG attatcattatcaatTAATAATATAGCAAGAAACctgttctccgtctatcactatttt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" CDS 3932781..3933746 /gene="frxB" /locus_tag="BSU_39610" /old_locus_tag="BSU39610" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 1c: Function from experimental evidences in the studied genus; PubMedId: 12354229, 16672620, 8388528, 19254027, 23924612, 25007174; Product type t : transporter" /codon_start=1 /transl_table=11 /product="desferrioxamine-and ferrichrome-binding transporter lipoprotein (shuttle system)" /protein_id="NP_391840.2" /db_xref="EnsemblGenomes-Gn:BSU39610" /db_xref="EnsemblGenomes-Tr:CAB15997" /db_xref="GOA:P54941" /db_xref="InterPro:IPR002491" /db_xref="SubtiList:BG11878" /db_xref="UniProtKB/Swiss-Prot:P54941" /translation="MKKNILLVGMLVLLLMFVSACSGTASKGSSSDSASEKTEMRTYK SPKGNVNIPAHPKRIVTDFYAGELLSVGANVVGSGSWSFDNPFLKSKLKNVKDVGDPI SVEKVMELQPDLIVVMNEENVDKLKKIAPTVVIPYNTAKNVEDTVSMFGDIAGAKDQA KSFMADFNKKAEAAKKKIAGVIDKDATFGIYENTDKGEFWVFNDNGGRGGQAVYNALG LKAPEKIEQDVIKKGEMKQLSQEVIPEYAADYMFITDYNPKGESKTLDKLENSSIWKN LDAVKHNRVFINDFDSFYPYDPISVSKQVDIITDMLIKRAEENKK*" gene 3932781..3933746 /gene="frxB" /locus_tag="BSU_39610" /old_locus_tag="BSU39610" upshifts 3933174 /Source="Nicolas_upshifts" /id="U3123" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.726273726273726" /psig="0.726273726273726" /xcortree=773 /SigmaFactorBS="cctgacttaattgttgtcatgaatgaagagaatgttgataaa ttaaagaaaatcgctccgactgttgTCATACCTTATAACACAGCgaaaaacgtagaag a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" misc_feature 3933181..3933199 /Source="Nicolas_upshift_promotors" /id="U3123" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.726273726273726" /psig="0.726273726273726" /xcortree=773 /SigmaFactorBS="cctgacttaattgttgtcatgaatgaagagaatgttgataaa ttaaagaaaatcgctccgactgttgTCATACCTTATAACACAGCgaaaaacgtagaag a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" downshifts 3933653 /Source="Nicolas_upshifts" /id="D2050" /incds=1 /nref=55 /ntot=191 /MaxReadThrough="6.103" /MaxDrop="4.3334" /score="22.3558496" /energy="-13.4" /TU="U3121" /idTUdmin="U3123" /TUdmin=193 /isTUend="FALSE" downshifts 3933724 /Source="Nicolas_upshifts" /id="D2051" /incds=0 /nref=1 /ntot=62 /MaxReadThrough="4.41732" /MaxDrop="3.7101" /score="22.3558496" /energy="-13.4" /TU="U3121" /idTUdmin="U3123" /TUdmin=264 /isTUend="FALSE" S_feature 3933769..3934565 /Source="Nicolas_S_feature" /locus_tag="new_4068171_4068967" /HighExp="H2O2, Paraq, Lbexp, dia0, LBGexp, G150, B36, dia15, B60, GM 25" /AntisenseName="yxeA" /AntisenseCor="0.20524492145617201" /AntisenseRegPval="-3.2" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1523" CDS complement(3933787..3934134) /gene="yxeA" /locus_tag="BSU_39620" /old_locus_tag="BSU39620" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_391841.1" /db_xref="EnsemblGenomes-Gn:BSU39620" /db_xref="EnsemblGenomes-Tr:CAB15998" /db_xref="InterPro:IPR006542" /db_xref="InterPro:IPR036166" /db_xref="PDB:3NPP" /db_xref="SubtiList:BG11877" /db_xref="UniProtKB/Swiss-Prot:P54940" /translation="MKKAMAILAVLAAAAVICGLLFFHNDVTDRFNPFIHQQDVYVQI DRDGRHLSPGGTEYTLDGYNASGKKEEVTFFAGKELRKNAYLKVKAKGKYVETWEEVK FEDMPDSVQSKLK*" gene complement(3933787..3934134) /gene="yxeA" /locus_tag="BSU_39620" /old_locus_tag="BSU39620" downshifts complement(3933800) /Source="Nicolas_upshifts" /id="D2052" /incds=0 /nref=2 /ntot=78 /MaxReadThrough="1.28842" /MaxDrop="2.99568" /score="38.5550476" /energy="-11.6" /TU="NA" /idTUdmin="U3120" /TUdmin="-1584" /isTUend="FALSE" CDS complement(3934148..3936016) /gene="tpeM" /locus_tag="BSU_39630" /old_locus_tag="BSU39630" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:15289557, 15849754, 15870467, 16850406, 21078927, 28472044" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15289557, 15849754, 15870467, 16850406, 21078927, 28472044; Product type t : transporter" /codon_start=1 /transl_table=11 /product="ABC transporter (permease); efflux of cationic peptides" /protein_id="NP_391842.2" /db_xref="EnsemblGenomes-Gn:BSU39630" /db_xref="EnsemblGenomes-Tr:CAB15999" /db_xref="GOA:P42424" /db_xref="InterPro:IPR003838" /db_xref="InterPro:IPR027022" /db_xref="SubtiList:BG11129" /db_xref="UniProtKB/Swiss-Prot:P42424" /translation="MTFLQFAYKNVTRNKRAYLAFFLSSAFSVLIFFTFAMFLFHPAL KEGYLNNIAKKGLTAAEWMIFVFSFLFVLYSVNAFLKSRNKEFGILLMQGITPGQLRK LITAENMIIGVMSIAAGIIGGFIFSKTFFTVGAYILEMDALPLYMPWKALGITACGFL LLFFFLSQFTILFVRSNTVIKLIKGTGKVKPEPKPSVLLSLFGIACLCGGYGMVLKGN VHGAEPFIILLLTVIGTYFFFSQSSIWILRALKKWKTFYLRGKNIIWVSDLVYRLKDN ARLFFIVSIISAVAFTATGVLAMYKSTVGAEESAYEMEYLSYSNNPKEQTHLKDIDHE LKTHGFTYTKDKIDVSYVRYQEGETVPPVYMISESDAAKYFHVKVNGLKEDEAVYFPG TYDRNFKNEAPDQLKLLNQKGELSDQKLSVKEVKKPLISLNAIIAVNDQTFDQLKSLG DKASLYGYSYDHWKDSLEISQSLQNEIYGNYIDVHSDFASKAGTYYDTVQLPSLSLFI GLFIAIVFFVAAASFLYFRLFTDLDEDRERYRSLAKIGLSEREMAQSVTIQLAILFFF PFVIAVMHTLFALRTLAVEGYSDVAGPLSLTIGGFFIFQLLFFLAVRSSYLKKMNK*" gene complement(3934148..3936016) /gene="tpeM" /locus_tag="BSU_39630" /old_locus_tag="BSU39630" CDS complement(3935991..3936764) /gene="tpeL" /locus_tag="BSU_39640" /old_locus_tag="BSU39640" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:15289557, 15870467, 17600057, 21078927, 28472044" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15289557, 15870467, 17600057, 21078927, 28472044; Product type t : transporter" /codon_start=1 /transl_table=11 /product="ABC transporter (ATP-binding protein); efflux ofcationic peptides" /protein_id="NP_391843.2" /db_xref="EnsemblGenomes-Gn:BSU39640" /db_xref="EnsemblGenomes-Tr:CAB16000" /db_xref="GOA:P42423" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR017871" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG11128" /db_xref="UniProtKB/Swiss-Prot:P42423" /translation="MANMLEVKHINKTYKGQVSYQALKQISFSIEEGEFTAVMGPSGS GKTTLLNIISTIDRPDSGDILINGENPHRLKRTKLAHFRRKQLGFVFQDFNLLDTLTI GENIMLPLTLEKEAPSVMEEKLHGIAAKLGIENLLNKRTFEVSGGQRQRAAIARAVIH KPSLILADEPTGNLDSKATKDVMETLQSLNRDDHVTALMVTHDPVSASYCRRVIFIKD GELFNEIYRGENRQVFYEQILDVLSMLGGNANDLSSVRL*" gene complement(3935991..3936764) /gene="tpeL" /locus_tag="BSU_39640" /old_locus_tag="BSU39640" CDS complement(3936908..3937885) /gene="tpeK" /locus_tag="BSU_39650" /old_locus_tag="BSU39650" /EC_number="2.7.13.3" /function="16.12: Sense" /experiment="publication(s) with functional evidences, PMID:11717295, 15289557, 15870467, 21283517, 25875741" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11717295, 15289557, 15870467, 21283517, 25875741; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="two-component sensor histidine kinase [YxdJ]" /protein_id="NP_391844.1" /db_xref="EnsemblGenomes-Gn:BSU39650" /db_xref="EnsemblGenomes-Tr:CAB16001" /db_xref="GOA:P42422" /db_xref="InterPro:IPR003594" /db_xref="InterPro:IPR003661" /db_xref="InterPro:IPR004358" /db_xref="InterPro:IPR005467" /db_xref="InterPro:IPR036890" /db_xref="SubtiList:BG11127" /db_xref="UniProtKB/Swiss-Prot:P42422" /translation="MKLFLRSHAVLILLFLLQGLFVFFYYWFAGLHSFSHLFYILGVQ LLILAGYLAYRWYKDRGVYHWLSSGQEGTDIPYLGSSVFCSELYEKQMELIRLQHQKL HETEAKLDARVTYMNQWVHQVKTPLSVINLIIQEEDEPVFEQIKKEVRQIEFGLETLL YSSRLDLFERDFKIEAVSLSELLQSVIQSYKRFFIQYRVYPKMNVCDDHQIYTDAKWL KFAIGQVVTNAVKYSAGKSDRLELNVFCDEDRTVLEVKDYGVGIPSQDIKRVFDPYYT GENGRRFQESTGIGLHLVKEITDKLNHTVDISSSPGEGTSVRFSFLTKM*" gene complement(3936908..3937885) /gene="tpeK" /locus_tag="BSU_39650" /old_locus_tag="BSU39650" CDS complement(3937882..3938571) /gene="tpeJ" /locus_tag="BSU_39660" /old_locus_tag="BSU39660" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:11717295, 15289557, 15870467, 21283517, 25875741" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11717295, 15289557, 15870467, 21283517, 25875741; Product type r: regulator" /codon_start=1 /transl_table=11 /product="two-component response regulator [TpeK(YxdK)]" /protein_id="NP_391845.1" /db_xref="EnsemblGenomes-Gn:BSU39660" /db_xref="EnsemblGenomes-Tr:CAB16002" /db_xref="GOA:P42421" /db_xref="InterPro:IPR001789" /db_xref="InterPro:IPR001867" /db_xref="InterPro:IPR011006" /db_xref="InterPro:IPR016032" /db_xref="InterPro:IPR036388" /db_xref="SubtiList:BG11126" /db_xref="UniProtKB/Swiss-Prot:P42421" /translation="MNKIMIVEDSEDIRGLLQNYLEKYGYQTVVAADFTAVLDVFLRE KPDVVLLDINLPAYDGYYWCRQIRQHSTSPIIFISARSGEMDQVMAIENGGDDYIEKP FSYDIVLAKIKSQIRRAYGEYAAKQGEKVVEYAGVQLFVERFELRFQDEKSELSKKES KLLEVLLERGEKVTSRDRLMEKTWDTDIFIDDNTLNVYITRLRKKLRELNAPVSIEAV RGEGYQLRAQS*" gene complement(3937882..3938571) /gene="tpeJ" /locus_tag="BSU_39660" /old_locus_tag="BSU39660" promotor_-10 complement(3938598..3938617) /Source="Nicolas_upshift_promotors" /id="U3124" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.440559440559441" /psig="0.963036963036963" /xcortree=1786 /SigmaFactorBS="agaccagaaaccgccgagatggcggtttttttgtgcggTGTT GCGtccatacgcccaaaACGATTATGATGATGGCAGCagtgtaagaaacgggagtggt t" /listShort="yxdJ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3938616) /Source="Nicolas_upshifts" /id="U3124" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.440559440559441" /psig="0.963036963036963" /xcortree=1786 /SigmaFactorBS="agaccagaaaccgccgagatggcggtttttttgtgcggTGTT GCGtccatacgcccaaaACGATTATGATGATGGCAGCagtgtaagaaacgggagtggt t" /listShort="yxdJ" /GFF_Attribute="listLong" promotor_-35 complement(3938632..3938638) /Source="Nicolas_upshift_promotors" /id="U3124" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.440559440559441" /psig="0.963036963036963" /xcortree=1786 /SigmaFactorBS="agaccagaaaccgccgagatggcggtttttttgtgcggTGTT GCGtccatacgcccaaaACGATTATGATGATGGCAGCagtgtaagaaacgggagtggt t" /listShort="yxdJ" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3938679..3939551) /gene="iolJ" /locus_tag="BSU_39670" /old_locus_tag="BSU39670" /EC_number="4.1.2.29" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:9226270, 10658656, 11325924, 18310071" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9226270, 10658656, 11325924, 18310071; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="2-deoxy-5-keto-D-gluconic acid 6-phosphate aldolase" /protein_id="NP_391846.1" /db_xref="EnsemblGenomes-Gn:BSU39670" /db_xref="EnsemblGenomes-Tr:CAB16003" /db_xref="GOA:P42420" /db_xref="InterPro:IPR000771" /db_xref="InterPro:IPR011289" /db_xref="InterPro:IPR013785" /db_xref="SubtiList:BG11125" /db_xref="UniProtKB/Swiss-Prot:P42420" /translation="MAFVSMKELLEDAKREQYAIGQFNINGLQWTKAILQAAQKEQSP VIAAASDRLVDYLGGFKTIAAMVGALIEDMAITVPVVLHLDHGSSAERCRQAIDAGFS SVMIDGSHQPIDENIAMTKEVTDYAAKHGVSVEAEVGTVGGMEDGLVGGVRYADITEC ERIVKETNIDALAAALGSVHGKYQGEPNLGFKEMEAISRMTDIPLVLHGASGIPQDQI KKAITLGHAKININTECMVAWTDETRRMFQENSDLYEPRGYLTPGIEAVEETVRSKMR EFGSAGKAAKQQVG*" gene complement(3938679..3939551) /gene="iolJ" /locus_tag="BSU_39670" /old_locus_tag="BSU39670" downshifts complement(3938683) /Source="Nicolas_upshifts" /id="D2053" /incds=0 /nref=89 /ntot=172 /MaxReadThrough="3.05314" /MaxDrop="6.87265" /score="26.7325466" /energy="-8.2" /TU="NA" /idTUdmin="U3126" /TUdmin=0 /isTUend="TRUE" CDS complement(3939572..3940408) /gene="iolI" /locus_tag="BSU_39680" /old_locus_tag="BSU39680" /EC_number="5.3.99.11" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:9887260, 11566986, 12112707, 17619021, 16461681, 18310071, 22720735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9887260, 11566986, 12112707, 17619021, 16461681, 18310071, 22720735; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="inosose isomerase" /protein_id="NP_391847.1" /db_xref="EnsemblGenomes-Gn:BSU39680" /db_xref="EnsemblGenomes-Tr:CAB16004" /db_xref="GOA:P42419" /db_xref="InterPro:IPR013022" /db_xref="InterPro:IPR036237" /db_xref="PDB:1I60" /db_xref="PDB:1I6N" /db_xref="SubtiList:BG11124" /db_xref="UniProtKB/Swiss-Prot:P42419" /translation="MKLCFNEATTLENSNLKLDLELCEKHGYDYIEIRTMDKLPEYLK DHSLDDLAEYFQTHHIKPLALNALVFFNNRDEKGHNEIITEFKGMMETCKTLGVKYVV AVPLVTEQKIVKEEIKKSSVDVLTELSDIAEPYGVKIALEFVGHPQCTVNTFEQAYEI VNTVNRDNVGLVLDSFHFHAMGSNIESLKQADGKKIFIYHIDDTEDFPIGFLTDEDRV WPGQGAIDLDAHLSALKEIGFSDVVSVELFRPEYYKLTAEEAIQTAKKTTVDVVSKYF SM*" gene complement(3939572..3940408) /gene="iolI" /locus_tag="BSU_39680" /old_locus_tag="BSU39680" S_feature complement(3940409..3940493) /Source="Nicolas_S_feature" /locus_tag="new_4074811_4074895_c" /HighExp="M40t90, M0t90, BI, Sw, BC, T5.0H, T0.30H, T4.0H, T3.30H, Mt0" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.101524" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="SigA" /TUlongPSig=1 /label="S1524" CDS complement(3940494..3941363) /gene="iolH" /locus_tag="BSU_39690" /old_locus_tag="BSU39690" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 9887260, 11566986, 12112707, 23874669; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative sugar-phosphate epimerase/isomerase" /protein_id="NP_391848.1" /db_xref="EnsemblGenomes-Gn:BSU39690" /db_xref="EnsemblGenomes-Tr:CAB16005" /db_xref="InterPro:IPR013022" /db_xref="InterPro:IPR036237" /db_xref="SubtiList:BG11123" /db_xref="UniProtKB/Swiss-Prot:P42418" /translation="MKLALDPSMYRDDLTLEEMVYKTAELGYEYIELSPREDFCPFYK YPKVDSAKIKQLKRLLRDTGVKLSSLLPLYHWAGPDEDRRQAAVRNWKRAIEIAVELE VDLMNSEFSGSKYDPLTSEEKFIKSMDELLPVFEKEGIKLNLQAHPYDFIETHKGAMD MIRALDKDWINLVYSTAHTFFYDDGKGDIETMFDEAGDRLTHVLFADTYNHKAAHGLR YIVNPPDAKVTVHQHLDIGQGEVDFDTIFRKLREMKFDGIATNAVFAWVDERADESSR FMLKKMKEELGLA*" gene complement(3940494..3941363) /gene="iolH" /locus_tag="BSU_39690" /old_locus_tag="BSU39690" CDS complement(3941383..3942417) /gene="iolG" /locus_tag="BSU_39700" /old_locus_tag="BSU39700" /EC_number="1.1.1.18" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:112095, 11274120, 15678175, 9226270, 16461681, 18310071, 22720735, 25482235, 28431560" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 112095, 11274120, 15678175, 9226270, 16461681, 18310071, 22720735, 25482235, 28431560; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="myo-inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase" /protein_id="NP_391849.2" /db_xref="EnsemblGenomes-Gn:BSU39700" /db_xref="EnsemblGenomes-Tr:CAB16006" /db_xref="GOA:P26935" /db_xref="InterPro:IPR000683" /db_xref="InterPro:IPR004104" /db_xref="InterPro:IPR023794" /db_xref="InterPro:IPR036291" /db_xref="PDB:3MZ0" /db_xref="PDB:3NT2" /db_xref="PDB:3NT4" /db_xref="PDB:3NT5" /db_xref="PDB:3NTO" /db_xref="PDB:3NTQ" /db_xref="PDB:3NTR" /db_xref="PDB:4L8V" /db_xref="PDB:4L9R" /db_xref="SubtiList:BG10669" /db_xref="UniProtKB/Swiss-Prot:P26935" /translation="MSLRIGVIGTGAIGKEHINRITNKLSGAEIVAVTDVNQEAAQKV VEQYQLNATVYPNDDSLLADENVDAVLVTSWGPAHESSVLKAIKAQKYVFCEKPLATT AEGCMRIVEEEIKVGKRLVQVGFMRRYDSGYVQLKEALDNHVIGEPLMIHCAHRNPTV GDNYTTDMAVVDTLVHEIDVLHWLVNDDYESVQVIYPKKSKNALPHLKDPQIVVIETK GGIVINAEIYVNCKYGYDIQCEIVGEDGIIKLPEPSSISLRKEGRFSTDILMDWQRRF VAAYDVEIQDFIDSIQKKGEVSGPTAWDGYIAAVTTDACVKAQESGQKEKVELKEKPE FYQSFTTVQN*" gene complement(3941383..3942417) /gene="iolG" /locus_tag="BSU_39700" /old_locus_tag="BSU39700" CDS complement(3942440..3943756) /gene="iolF" /locus_tag="BSU_39710" /old_locus_tag="BSU39710" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:11807058, 15849754, 16850406, 22720735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11807058, 15849754, 16850406, 22720735; Product type t: transporter" /codon_start=1 /transl_table=11 /product="inositol transport protein" /protein_id="NP_391850.2" /db_xref="EnsemblGenomes-Gn:BSU39710" /db_xref="EnsemblGenomes-Tr:CAB16007" /db_xref="GOA:P42417" /db_xref="InterPro:IPR005829" /db_xref="InterPro:IPR011701" /db_xref="InterPro:IPR020846" /db_xref="InterPro:IPR036259" /db_xref="SubtiList:BG11122" /db_xref="UniProtKB/Swiss-Prot:P42417" /translation="MGNTNGDSAFNKRTIAAALANYIDAGSIVAGSAGLSLWVSYLKL SDTQIGLLGALSANAISAAVGALLGGFLADKVGRKAVYTNSMLVYALGICLVLFGVNF PMLLSGYIIIGLSVGADITASWTIIAENAPKKNRARHCGVAQVAWAAGAVVVLLLSVL AGDLGLLGNKIVFAHLLVIALITYILRIRLPESDAWQTKNQPEEAQAEKPAVLNKTSY FDLLKPMYLKSILFLMGVYLVWNLAAGVMGFFMPYIYQQVGGVSANMANLLQMGLFIF TGLGVALIFMPFADKYRKTVFGIAAFMAVIGWTLFLLPVEGLPILLLFIVVIGINNGA GQQANYQLWASEIFPTQYRASAQGLMFFLVRISIGIWSLFVPMIITNFGIGTMAAILL GCVTASMIIGLLFAPNTSGKSLEQIQEELYGSPQSQVKKGTESKIM*" gene complement(3942440..3943756) /gene="iolF" /locus_tag="BSU_39710" /old_locus_tag="BSU39710" CDS complement(3943771..3944664) /gene="iolE" /locus_tag="BSU_39720" /old_locus_tag="BSU39720" /EC_number="4.2.1.44" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:9226270, 14993306, 22720735, 28693424" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9226270, 14993306, 22720735, 28693424; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="scyllo-inosose dehydratase" /protein_id="NP_391851.1" /db_xref="EnsemblGenomes-Gn:BSU39720" /db_xref="EnsemblGenomes-Tr:CAB16008" /db_xref="GOA:P42416" /db_xref="InterPro:IPR013022" /db_xref="InterPro:IPR023952" /db_xref="InterPro:IPR030823" /db_xref="InterPro:IPR036237" /db_xref="SubtiList:BG11121" /db_xref="UniProtKB/Swiss-Prot:P42416" /translation="MGKNEILWGIAPIGWRNDDMPEIGAGNTLQHLLSDIVVARFQGT EVGGFFPEPAILNKELKLRNLRIAGKWFSSFILRDGLGEAAKTFTLHCEYLQQVNADV AVVSEQTYSVQSLEKNVFTEKPHFTDDEWERLCEGLNHLGEIAAQHGLKLVYHHHLGT GVQTAEEVDRLMAGTDPAHVHLLYDTGHAYISDGDYMGMLEKHIGRIKHVHFKDARLN VMEQCRLEGQSFRQSFLKGMFTVPGDGCIDFREVYQLLLKHSYSGWIVIEAEQDPDVA NPLEYALIARNYIDQQLLDLA*" gene complement(3943771..3944664) /gene="iolE" /locus_tag="BSU_39720" /old_locus_tag="BSU39720" CDS complement(3944681..3946594) /gene="iolD" /locus_tag="BSU_39730" /old_locus_tag="BSU39730" /EC_number="3.7.1.22" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:9887260, 11566986, 12112707, 18310071, 22720735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9887260, 11566986, 12112707, 18310071, 22720735; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase" /protein_id="NP_391852.2" /db_xref="EnsemblGenomes-Gn:BSU39730" /db_xref="EnsemblGenomes-Tr:CAB16009" /db_xref="GOA:P42415" /db_xref="InterPro:IPR000399" /db_xref="InterPro:IPR011766" /db_xref="InterPro:IPR012000" /db_xref="InterPro:IPR012001" /db_xref="InterPro:IPR023757" /db_xref="InterPro:IPR029035" /db_xref="InterPro:IPR029061" /db_xref="InterPro:IPR030817" /db_xref="SubtiList:BG11120" /db_xref="UniProtKB/Swiss-Prot:P42415" /translation="MGKKIRLTTAQALIKFLNQQYIHVDGKEEPFVEGIFTIFGHGNV LGIGQALEQDAGHLKVYQGKNEQGMAHAAMAYSKQMLRRKIYAVSTSVGPGAANLVAA AGTALANNIPVLLIPADTFATRQPDPVLQQMEQEYSAAITTNDALKPVSRYWDRITRP EQLMSSLLRAFEVMTDPAKAGPATICISQDVEGEAYDFDESFFVKRVHYIDRMQPSER ELQGAAELIKSSKKPVILVGGGAKYSGARDELVAISEAYNIPLVETQAGKSTVEADFA NNLGGMGITGTLAANKAARQADLIIGIGTRYTDFATSSKTAFDFDKAKFLNINVSRMQ AYKLDAFQVVADAKVTLGKLHGLLEGYESEFGTTIRELKDEWLAERERLSKVTFKREA FDPEIKNHFSQEVLNEYADALNTELPQTTALLTINETIPEDSVIICSAGSLPGDLQRL WHSNVPNTYHLEYGYSCMGYEVSGTLGLKLAHPDREVYSIVGDGSFLMLHSELITAIQ YNKKINVLLFDNSGFGCINNLQMDHGSGSYYCEFRTDDNQILNVDYAKVAEGYGAKTY RANTVEELKAALEDAKKQDVSTLIEMKVLPKTMTDGYDSWWHVGVAEVSEQESVQKAY EAKEKKLESAKQY*" gene complement(3944681..3946594) /gene="iolD" /locus_tag="BSU_39730" /old_locus_tag="BSU39730" CDS complement(3946627..3947604) /gene="iolC" /locus_tag="BSU_39740" /old_locus_tag="BSU39740" /EC_number="2.7.1.92" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:9887260, 11566986, 12112707, 18310071, 22720735, 23874669" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9887260, 11566986, 12112707, 18310071, 22720735, 23874669; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="2-deoxy-5-keto-D-gluconic acid kinase" /protein_id="NP_391853.1" /db_xref="EnsemblGenomes-Gn:BSU39740" /db_xref="EnsemblGenomes-Tr:CAB16010" /db_xref="GOA:P42414" /db_xref="InterPro:IPR002173" /db_xref="InterPro:IPR011611" /db_xref="InterPro:IPR022841" /db_xref="InterPro:IPR023314" /db_xref="InterPro:IPR029056" /db_xref="InterPro:IPR030830" /db_xref="SubtiList:BG11119" /db_xref="UniProtKB/Swiss-Prot:P42414" /translation="MKYTFNEEKAFDIVAIGRACIDLNAVEYNRPMEETMTFSKYVGG SPANIAIGSAKLGLKAGFIGKIPDDQHGRFIESYMRKTGVDTTQMIVDQDGHKAGLAF TEILSPEECSILMYRDDVADLYLEPSEVSEDYIANAKMLLVSGTALAKSPSREAVLKA VQYAKKHQVKVVFELDYRPYTWQSSDETAVYYSLVAEQSDIVIGTRDEFDVMENRTGG SNEESVNHLFGHSADLVVIKHGVEGSYAYSKSGEVFRAQAYKTKVLKTFGAGDSYASA FIYGLVSGKDIETALKYGSASASIVVSKHSSSEAMPTAEEIEQLIEAQS*" gene complement(3946627..3947604) /gene="iolC" /locus_tag="BSU_39740" /old_locus_tag="BSU39740" CDS complement(3947628..3948443) /gene="iolB" /locus_tag="BSU_39750" /old_locus_tag="BSU39750" /EC_number="5.3.1.30" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:9887260, 11566986, 12112707, 18310071, 22720735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9887260, 11566986, 12112707, 18310071, 22720735; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="5-deoxy-D-glucuronic acid isomerase" /protein_id="NP_391854.2" /db_xref="EnsemblGenomes-Gn:BSU39750" /db_xref="EnsemblGenomes-Tr:CAB16011" /db_xref="GOA:P42413" /db_xref="InterPro:IPR011051" /db_xref="InterPro:IPR014710" /db_xref="InterPro:IPR021120" /db_xref="InterPro:IPR023770" /db_xref="InterPro:IPR024203" /db_xref="SubtiList:BG11118" /db_xref="UniProtKB/Swiss-Prot:P42413" /translation="MSYLLRKPQSHEVSNGVKLVHEVTTSNSDLTYVEFKVLDLASGS SYTEELKKQEICIVAVTGKITVTDHESTFENIGTRESVFERKPTDSVYISNDRAFEIT AVSDARVALCYSPSEKQLPTKLIKAEDNGIEHRGQFSNKRTVHNILPDSDPSANSLLV VEVYTDSGNWSSYPPHKHDQDNLPEESFLEETYYHELDPGQGFVFQRVYTDDRSIDET MTVGNENVVIVPAGYHPVGVPDGYTSYYLNVMAGPTRKWKFYNDPAHEWILER*" gene complement(3947628..3948443) /gene="iolB" /locus_tag="BSU_39750" /old_locus_tag="BSU39750" S_feature complement(3948444..3948517) /Source="Nicolas_S_feature" /locus_tag="new_4082846_4082919_c" /HighExp="M40t90, M0t90, Lbtran, BI, Mt0, T0.30H, Sw, BC, S1, T1.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="SigA" /TUlongPSig=1 /label="S1525" CDS complement(3948518..3949981) /gene="iolA" /locus_tag="BSU_39760" /old_locus_tag="BSU39760" /EC_number="1.2.1.27" /EC_number="1.2.1.18" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:10658656, 11566986, 16332250, 18310071, 20971862, 22720735, 26832667" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10658656, 11566986, 16332250, 18310071, 20971862, 22720735, 26832667; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="methylmalonate-semialdehyde dehydrogenase" /protein_id="NP_391855.1" /db_xref="EnsemblGenomes-Gn:BSU39760" /db_xref="EnsemblGenomes-Tr:CAB16012" /db_xref="GOA:P42412" /db_xref="InterPro:IPR010061" /db_xref="InterPro:IPR015590" /db_xref="InterPro:IPR016160" /db_xref="InterPro:IPR016161" /db_xref="InterPro:IPR016162" /db_xref="InterPro:IPR023510" /db_xref="PDB:1T90" /db_xref="SubtiList:BG11117" /db_xref="UniProtKB/Swiss-Prot:P42412" /translation="MAEIRKLKNYINGEWVESKTDQYEDVVNPATKEVLCQVPISTKE DIDYAAQTAAEAFKTWSKVAVPRRARILFNFQQLLSQHKEELAHLITIENGKNTKEAL GEVGRGIENVEFAAGAPSLMMGDSLASIATDVEAANYRYPIGVVGGIAPFNFPMMVPC WMFPMAIALGNTFILKPSERTPLLTEKLVELFEKAGLPKGVFNVVYGAHDVVNGILEH PEIKAISFVGSKPVGEYVYKKGSENLKRVQSLTGAKNHTIVLNDANLEDTVTNIVGAA FGSAGERCMACAVVTVEEGIADEFMAKLQEKVADIKIGNGLDDGVFLGPVIREDNKKR TLSYIEKGLEEGARLVCDGRENVSDDGYFVGPTIFDNVTTEMTIWKDEIFAPVLSVIR VKNLKEAIEIANKSEFANGACLFTSNSNAIRYFRENIDAGMLGINLGVPAPMAFFPFS GWKSSFFGTLHANGKDSVDFYTRKKVVTARYPAPDFN*" gene complement(3948518..3949981) /gene="iolA" /locus_tag="BSU_39760" /old_locus_tag="BSU39760" S_feature complement(3949982..3950186) /Source="Nicolas_S_feature" /locus_tag="new_4084384_4084588_c" /HighExp="M0t90, M40t90, Lbtran, BI, Mt0, T0.30H, BC, S1, T1.0H, Diami" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="SigA" /TUlongPSig=1 /label="S1526" promotor_-35 3949985..3949992 /Source="Nicolas_upshift_promotors" /id="U3125" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.626373626373626" /psig="0.788211788211788" /xcortree=1805 /SigmaFactorBS="gttttttaattttctgatttctgccattctTATTGCCTcctt cattagtaaacACATACACTTGTATGGATGGttccggatagattcatatcaatatcca c" /listShort="S1527" /listLong="iolR, iolS" /label="promotor_-35" promotor_-10 3950008..3950027 /Source="Nicolas_upshift_promotors" /id="U3125" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.626373626373626" /psig="0.788211788211788" /xcortree=1805 /SigmaFactorBS="gttttttaattttctgatttctgccattctTATTGCCTcctt cattagtaaacACATACACTTGTATGGATGGttccggatagattcatatcaatatcca c" /listShort="S1527" /listLong="iolR, iolS" /label="promotor_-10" upshifts 3950015 /Source="Nicolas_upshifts" /id="U3125" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.626373626373626" /psig="0.788211788211788" /xcortree=1805 /SigmaFactorBS="gttttttaattttctgatttctgccattctTATTGCCTcctt cattagtaaacACATACACTTGTATGGATGGttccggatagattcatatcaatatcca c" /listShort="S1527" /listLong="iolR, iolS" S_feature 3950022..3950328 /Source="Nicolas_S_feature" /locus_tag="new_4084424_4084730" /HighExp="G180, Paraq, G150, Oxctl, H2O2, G135, Diami, LBGexp, dia5, dia0" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.788" /TUlongSig="NA" /TUlongPSig="NA" /label="S1527" promotor_-10 complement(3950168..3950187) /Source="Nicolas_upshift_promotors" /id="U3126" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.99100899100899" /psig=1 /xcortree=331 /SigmaFactorBS="taatataataaaaataatgaaaaaatgtagtgtttatGATTG ACTtatgggtattatgcGATTAGAATATAACCAAGAAatgaccaaaaagtaacctgtt g" /listShort="S1526, mmsA, S1525, iolB, iolC, iolD, iolE, iolF, iolG, iolH, S1524, iolI, iolJ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3950186) /Source="Nicolas_upshifts" /id="U3126" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.99100899100899" /psig=1 /xcortree=331 /SigmaFactorBS="taatataataaaaataatgaaaaaatgtagtgtttatGATTG ACTtatgggtattatgcGATTAGAATATAACCAAGAAatgaccaaaaagtaacctgtt g" /listShort="S1526, mmsA, S1525, iolB, iolC, iolD, iolE, iolF, iolG, iolH, S1524, iolI, iolJ" /GFF_Attribute="listLong" S_feature complement(3950188..3950340) /Source="Nicolas_S_feature" /locus_tag="new_4084590_4084742_c" /HighExp="M40t90, M0t90, Lbtran, Diami, Heat, dia5, C30, BI, S1, Mt0" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1528" promotor_-35 complement(3950202..3950209) /Source="Nicolas_upshift_promotors" /id="U3126" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.99100899100899" /psig=1 /xcortree=331 /SigmaFactorBS="taatataataaaaataatgaaaaaatgtagtgtttatGATTG ACTtatgggtattatgcGATTAGAATATAACCAAGAAatgaccaaaaagtaacctgtt g" /listShort="S1526, mmsA, S1525, iolB, iolC, iolD, iolE, iolF, iolG, iolH, S1524, iolI, iolJ" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 3950288..3950295 /Source="Nicolas_upshift_promotors" /id="U3127" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.95004995004995" /psig="0.99000999000999" /xcortree=329 /SigmaFactorBS="taagagaaggccgtccaaTCTTGCAAaagatatacaccgaTG TTATCATTTTTAAGCAACtattgattaacttttggtttttattatatatttatgttac g" /listShort="iolR, iolS" /listLong="S1529, yxcE, yxcD" /label="promotor_-35" promotor_-10 3950310..3950329 /Source="Nicolas_upshift_promotors" /id="U3127" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.95004995004995" /psig="0.99000999000999" /xcortree=329 /SigmaFactorBS="taagagaaggccgtccaaTCTTGCAAaagatatacaccgaTG TTATCATTTTTAAGCAACtattgattaacttttggtttttattatatatttatgttac g" /listShort="iolR, iolS" /listLong="S1529, yxcE, yxcD" /label="promotor_-10" upshifts 3950330 /Source="Nicolas_upshifts" /id="U3127" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.95004995004995" /psig="0.99000999000999" /xcortree=329 /SigmaFactorBS="taagagaaggccgtccaaTCTTGCAAaagatatacaccgaTG TTATCATTTTTAAGCAACtattgattaacttttggtttttattatatatttatgttac g" /listShort="iolR, iolS" /listLong="S1529, yxcE, yxcD" promotor_-10 complement(3950341..3950360) /Source="Nicolas_upshift_promotors" /id="U3128" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.861138861138861" /psig=1 /xcortree=332 /SigmaFactorBS="ctgaatccgcatcagtttcatataaaaaactcctTCTTGAAT ctttacgtaacataaATATATAATAAAAACCAAAAgttaatcaatagttgcttaaaaa t" /listShort="S1528" /listLong="S1526, mmsA, S1525, iolB, iolC, iolD, iolE, iolF, iolG, iolH, S1524, iolI, iolJ" /label="promotor_-10" upshifts complement(3950357) /Source="Nicolas_upshifts" /id="U3128" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.861138861138861" /psig=1 /xcortree=332 /SigmaFactorBS="ctgaatccgcatcagtttcatataaaaaactcctTCTTGAAT ctttacgtaacataaATATATAATAAAAACCAAAAgttaatcaatagttgcttaaaaa t" /listShort="S1528" /listLong="S1526, mmsA, S1525, iolB, iolC, iolD, iolE, iolF, iolG, iolH, S1524, iolI, iolJ" promotor_-35 complement(3950376..3950383) /Source="Nicolas_upshift_promotors" /id="U3128" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.861138861138861" /psig=1 /xcortree=332 /SigmaFactorBS="ctgaatccgcatcagtttcatataaaaaactcctTCTTGAAT ctttacgtaacataaATATATAATAAAAACCAAAAgttaatcaatagttgcttaaaaa t" /listShort="S1528" /listLong="S1526, mmsA, S1525, iolB, iolC, iolD, iolE, iolF, iolG, iolH, S1524, iolI, iolJ" /label="promotor_-35" CDS 3950397..3951152 /gene="iolR" /locus_tag="BSU_39770" /old_locus_tag="BSU39770" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:9887260, 11566986, 11807058, 18310071, 24878601, 26735940" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9887260, 11566986, 11807058, 18310071, 24878601, 26735940; Product type r : regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator of the iol operon (DeoR family)" /protein_id="NP_391856.1" /db_xref="EnsemblGenomes-Gn:BSU39770" /db_xref="EnsemblGenomes-Tr:CAB16013" /db_xref="GOA:P46337" /db_xref="InterPro:IPR001034" /db_xref="InterPro:IPR014036" /db_xref="InterPro:IPR018356" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG11364" /db_xref="UniProtKB/Swiss-Prot:P46337" /translation="MKLMRIQEMEEYILSHGTVSLDELCQVFNVSKNTVRRDINKLTE KGAIEKVYGGVTSIEKTALVPFENRTIQHQDEKTKIAHYASRFIEDHDLVFIDSGTTT KSILDTLDPAKNVTILTNSLDIINAASALKNINLIIIGNNYKRKTRSFVGMDDPAMLD KYNINKAFMSATGTTLTHGLTNSDLLEYEIKKRISEKAKEVYLLADHSKFGKSTLLTY APFDRLHCIVTSQPLDDEYTQYCNEHQIGIHLA*" gene 3950397..3951152 /gene="iolR" /locus_tag="BSU_39770" /old_locus_tag="BSU39770" promotor_-35 3951131..3951137 /Source="Nicolas_upshift_promotors" /id="U3129" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.841158841158841" /psig="0.994005994005994" /xcortree=2059 /SigmaFactorBS="acacgcagtactgcaatgagcatcaAATCGGCattcatctgg cctaACGTTTACAATAGTGTTGAGagtctatcatccattttattctaggaggcagatc a" /listShort="iolS, S1529, yxcE, yxcD" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3951152..3951171 /Source="Nicolas_upshift_promotors" /id="U3129" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.841158841158841" /psig="0.994005994005994" /xcortree=2059 /SigmaFactorBS="acacgcagtactgcaatgagcatcaAATCGGCattcatctgg cctaACGTTTACAATAGTGTTGAGagtctatcatccattttattctaggaggcagatc a" /listShort="iolS, S1529, yxcE, yxcD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3951166 /Source="Nicolas_upshifts" /id="U3129" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.841158841158841" /psig="0.994005994005994" /xcortree=2059 /SigmaFactorBS="acacgcagtactgcaatgagcatcaAATCGGCattcatctgg cctaACGTTTACAATAGTGTTGAGagtctatcatccattttattctaggaggcagatc a" /listShort="iolS, S1529, yxcE, yxcD" /GFF_Attribute="listLong" CDS 3951206..3952138 /gene="iolS" /locus_tag="BSU_39780" /old_locus_tag="BSU39780" /EC_number="1.1.1.-" /function="16.11: Scavenge (Catabolism)" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 9226270, 15019785, 22720735, 24330391; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative aldo-keto reductase" /protein_id="NP_391857.1" /db_xref="EnsemblGenomes-Gn:BSU39780" /db_xref="EnsemblGenomes-Tr:CAB16014" /db_xref="GOA:P46336" /db_xref="InterPro:IPR018170" /db_xref="InterPro:IPR020471" /db_xref="InterPro:IPR023210" /db_xref="InterPro:IPR036812" /db_xref="PDB:1PYF" /db_xref="PDB:1PZ0" /db_xref="SubtiList:BG11363" /db_xref="UniProtKB/Swiss-Prot:P46336" /translation="MKKAKLGKSDLQVFPIGLGTNAVGGHNLYPNLNEETGKELVREA IRNGVTMLDTAYIYGIGRSEELIGEVLREFNREDVVIATKAAHRKQGNDFVFDNSPDF LKKSVDESLKRLNTDYIDLFYIHFPDEHTPKDEAVNALNEMKKAGKIRSIGVSNFSLE QLKEANKDGLVDVLQGEYNLLNREAEKTFFPYTKEHNISFIPYFPLVSGLLAGKYTED TTFPEGDLRNEQEHFKGERFKENIRKVNKLAPIAEKHNVDIPHIVLAWYLARPEIDIL IPGAKRADQLIDNIKTADVTLSQEDISFIDKLFA*" gene 3951206..3952138 /gene="iolS" /locus_tag="BSU_39780" /old_locus_tag="BSU39780" downshifts 3952140 /Source="Nicolas_upshifts" /id="D2054" /incds=0 /nref=154 /ntot=259 /MaxReadThrough="4.521" /MaxDrop="7.17874" /score="39.70215" /energy="-17.1" /TU="U3129" /idTUdmin="U3127" /TUdmin=6 /isTUend="TRUE" promotor_-35 3952217..3952224 /Source="Nicolas_upshift_promotors" /id="U3130" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.703296703296703" /psig="0.835164835164835" /xcortree=2016 /SigmaFactorBS="ataaattcctaaataactgattttgaagcaaaaCCTTACAAa atgagccataaaTCCGATAAAATAAAGGTAGTttatctcagaaagaaagtgattgaga a" /listShort="S1529, yxcE, yxcD" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3952238..3952257 /Source="Nicolas_upshift_promotors" /id="U3130" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.703296703296703" /psig="0.835164835164835" /xcortree=2016 /SigmaFactorBS="ataaattcctaaataactgattttgaagcaaaaCCTTACAAa atgagccataaaTCCGATAAAATAAAGGTAGTttatctcagaaagaaagtgattgaga a" /listShort="S1529, yxcE, yxcD" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 3952244..3952399 /Source="Nicolas_S_feature" /locus_tag="new_4086646_4086801" /HighExp="dia5, LPhT, Diami, Etha, dia15, LBGstat, M9-stat, Lbtran, T0.30H, C30" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="0.835, 0.994" /TUlongSig="SigA" /TUlongPSig="0.99" /label="S1529" upshifts 3952244 /Source="Nicolas_upshifts" /id="U3130" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.703296703296703" /psig="0.835164835164835" /xcortree=2016 /SigmaFactorBS="ataaattcctaaataactgattttgaagcaaaaCCTTACAAa atgagccataaaTCCGATAAAATAAAGGTAGTttatctcagaaagaaagtgattgaga a" /listShort="S1529, yxcE, yxcD" /GFF_Attribute="listLong" CDS 3952400..3953050 /gene="yxcE" /locus_tag="BSU_39790" /old_locus_tag="BSU39790" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_391858.1" /db_xref="EnsemblGenomes-Gn:BSU39790" /db_xref="EnsemblGenomes-Tr:CAB16015" /db_xref="GOA:P46335" /db_xref="SubtiList:BG11362" /db_xref="UniProtKB/Swiss-Prot:P46335" /translation="MKLKYVKALVAVTVALGVLLPSTISHAKSFSGRSSSSYSSRSSS SSYSGSYKSSPKSSYSSGSSSSSKKSKTSDDSSSSISLKKKPSEKASSSSSKKSSGTF SGATSKVTGKTYSGKTSKAYVGGRYVSVNHYYHAGFAPSGWFGYYSGFTMGMFMISMM HPWGYTYHPVGGPGYVSYGASPIAWIVDIIALIIILIIVIALIRAFKAPKTYRRRF*" gene 3952400..3953050 /gene="yxcE" /locus_tag="BSU_39790" /old_locus_tag="BSU39790" CDS 3953054..3953362 /gene="yxcD" /locus_tag="BSU_39800" /old_locus_tag="BSU39800" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_391859.1" /db_xref="EnsemblGenomes-Gn:BSU39800" /db_xref="EnsemblGenomes-Tr:CAB16016" /db_xref="InterPro:IPR020516" /db_xref="SubtiList:BG11361" /db_xref="UniProtKB/Swiss-Prot:P46334" /translation="MRLILNEQEIVDGICVYISNEEDIYPEDVEVKELSYNKRTGFFA EATFGLHHKQLMSDDISEGIIQFLEEYHNFNPDVTVVELQFDKKKGFSALVFVNEAEE *" gene 3953054..3953362 /gene="yxcD" /locus_tag="BSU_39800" /old_locus_tag="BSU39800" downshifts 3953364 /Source="Nicolas_upshifts" /id="D2055" /incds=0 /nref=185 /ntot=262 /MaxReadThrough="1.91541" /MaxDrop="6.4314" /score="14.1581732" /energy="-8.8" /TU="NA" /idTUdmin="U3130" /TUdmin="-2" /isTUend="TRUE" promotor_-35 3953506..3953512 /Source="Nicolas_upshift_promotors" /id="U3131" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=218 /SigmaFactorBS="tataaagtttccgttttttcaaaacaaaTGTTTCAaatgaga taggaaatGGGTACTAATCTATTAACTttgttacatatttttagatactcattggctc a" /listShort="csbC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3953528..3953546 /Source="Nicolas_upshift_promotors" /id="U3131" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=218 /SigmaFactorBS="tataaagtttccgttttttcaaaacaaaTGTTTCAaatgaga taggaaatGGGTACTAATCTATTAACTttgttacatatttttagatactcattggctc a" /listShort="csbC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3953538 /Source="Nicolas_upshifts" /id="U3131" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=218 /SigmaFactorBS="tataaagtttccgttttttcaaaacaaaTGTTTCAaatgaga taggaaatGGGTACTAATCTATTAACTttgttacatatttttagatactcattggctc a" /listShort="csbC" /GFF_Attribute="listLong" CDS 3953600..3954985 /gene="csbC" /locus_tag="BSU_39810" /old_locus_tag="BSU39810" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 10376822, 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative metabolite transporter" /protein_id="NP_391860.1" /db_xref="EnsemblGenomes-Gn:BSU39810" /db_xref="EnsemblGenomes-Tr:CAB16017" /db_xref="GOA:P46333" /db_xref="InterPro:IPR003663" /db_xref="InterPro:IPR005828" /db_xref="InterPro:IPR005829" /db_xref="InterPro:IPR020846" /db_xref="InterPro:IPR036259" /db_xref="SubtiList:BG11360" /db_xref="UniProtKB/Swiss-Prot:P46333" /translation="MKKDTRKYMIYFFGALGGLLYGYDTGVISGALLFINNDIPLTTL TEGLVVSMLLLGAIFGSALSGTCSDRWGRRKVVFVLSIIFIIGALACAFSQTIGMLIA SRVILGLAVGGSTALVPVYLSEMAPTKIRGTLGTMNNLMIVTGILLAYIVNYLFTPFE AWRWMVGLAAVPAVLLLIGIAFMPESPRWLVKRGSEEEARRIMNITHDPKDIEMELAE MKQGEAEKKETTLGVLKAKWIRPMLLIGVGLAIFQQAVGINTVIYYAPTIFTKAGLGT SASALGTMGIGILNVIMCITAMILIDRVGRKKLLIWGSVGITLSLAALSGVLLTLGLS ASTAWMTVVFLGVYIVFYQATWGPVVWVLMPELFPSKARGAATGFTTLVLSAANLIVS LVFPLMLSAMGIAWVFMVFSVICLLSFFFAFYMVPETKGKSLEEIEASLKKRFKKKKS TQNQVLNERTL*" gene 3953600..3954985 /gene="csbC" /locus_tag="BSU_39810" /old_locus_tag="BSU39810" downshifts 3954971 /Source="Nicolas_upshifts" /id="D2056" /incds=0 /nref=69 /ntot=115 /MaxReadThrough="4.59405" /MaxDrop="7.32264" /score="22.9943012" /energy="-16.4" /TU="NA" /idTUdmin="U3131" /TUdmin=0 /isTUend="TRUE" S_feature 3955016..3955566 /Source="Nicolas_S_feature" /locus_tag="new_4089418_4089968" /HighExp="Etha, C30, C90, Gly, Sw, G135, Fru, HiTm, M/G, Mal" /AntisenseName="htpG" /AntisenseCor="7.4766600377621104E-2" /AntisenseRegPval="-0.7" /CDS_PredictionProba="NA" /TUshortSig="NA" /TUshortPSig="NA" /TUlongSig="NA" /TUlongPSig="NA" /label="S1530" CDS complement(3955027..3956907) /gene="htpG" /locus_tag="BSU_39820" /old_locus_tag="BSU39820" /function="16.6: Maintain" /experiment="publication(s) with functional evidences, PMID:9150201, 10323241, 11407116, 12511492, 22226636, 26743745, 27723736, 28363677, 28383119, 28784328" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9150201, 10323241, 11407116, 12511492, 22226636, 26743745, 27723736, 28363677, 28383119, 28784328; Product type f: factor" /codon_start=1 /transl_table=11 /product="class III heat-shock protein (ATP-dependent molecular chaperone HSP90)" /protein_id="NP_391861.1" /db_xref="EnsemblGenomes-Gn:BSU39820" /db_xref="EnsemblGenomes-Tr:CAB16018" /db_xref="GOA:P46208" /db_xref="InterPro:IPR001404" /db_xref="InterPro:IPR003594" /db_xref="InterPro:IPR019805" /db_xref="InterPro:IPR020568" /db_xref="InterPro:IPR020575" /db_xref="InterPro:IPR036890" /db_xref="InterPro:IPR037196" /db_xref="SubtiList:BG11359" /db_xref="UniProtKB/Swiss-Prot:P46208" /translation="MAKKEFKAESKRLLDMMINSIYTQKEIFLRELISNSSDAIDKIY YKALTDDALTFDKDSYYIKVAADKDARTLTISDTGIGMTKDELEQHLGTIAKSGSLAF KKENELKDGHDIIGQFGVGFYAAFMVADVVTVISKALGSEEAYKWESAGADGYTIEPC EKDSVGTDIILKIKENTEDDSYDEFLEEYRLKAIIKKYSDFIRYPIKMDTTINKPKEG SENEFEEVQEEQTVNSMVPIWRKNKSELTDEDYEKFYAEKHYGFDKPLTHVHISVDGA VRYNAILFVPENMPFDYYSKEYEKGLELYSNGVLIMNKCADLLPDHFSFVKGMVDSED LSLNISREMLQHDRQLKLIAKNISKKIKSELQSLLKKDREKYETFYKSFGRQLKFGVY NDFGANKDQLKDLLLFYSSKEKKLVSLDEYVSRMPEEQKFIYYATGDSYDRIEKLPQT EMVADKGYEILYFTEDIDEFAIKMLASYQEKEFKSVSSGDLGIDTDEDQKQSEEEESK YKDLFEEMKNILSDKVKNVRISKRLKSHPVCLAADGEVTIEMEKILNAMPDSQNVKAE KVLEINPNHEVFQTLQDAFEQDKEKLSLYTNLLYNQALLIEGLPIQDPVEFTNNICKV MV*" gene complement(3955027..3956907) /gene="htpG" /locus_tag="BSU_39820" /old_locus_tag="BSU39820" downshifts complement(3955033) /Source="Nicolas_upshifts" /id="D2057" /incds=0 /nref=169 /ntot=288 /MaxReadThrough="0.81611" /MaxDrop="6.49379" /score="34.0973015" /energy="-16.4" /TU="NA" /idTUdmin="U3132" /TUdmin="-8" /isTUend="TRUE" S_feature complement(3956908..3957005) /Source="Nicolas_S_feature" /locus_tag="new_4091310_4091407_c" /HighExp="Lbtran, S1, LBGtran, C90, M40t45, M9-tran, GM 150, dia0, T-2.40H, dia5" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.996" /TUlongSig="SigA" /TUlongPSig="0.995" /label="S1531" promotor_-10 complement(3956996..3957015) /Source="Nicolas_upshift_promotors" /id="U3132" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.69030969030969" /psig="0.996003996003996" /xcortree=2301 /SigmaFactorBS="tcttttttatgagaatgagtgagaaaaaGAGTGAAAacaaat ccaactaaTGTTAAATTTACATATATATgcatctatcaatctaattgacaattgtcat c" /listShort="S1531, htpG" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3957005) /Source="Nicolas_upshifts" /id="U3132" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.69030969030969" /psig="0.996003996003996" /xcortree=2301 /SigmaFactorBS="tcttttttatgagaatgagtgagaaaaaGAGTGAAAacaaat ccaactaaTGTTAAATTTACATATATATgcatctatcaatctaattgacaattgtcat c" /listShort="S1531, htpG" /GFF_Attribute="listLong" promotor_-35 complement(3957030..3957037) /Source="Nicolas_upshift_promotors" /id="U3132" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.69030969030969" /psig="0.996003996003996" /xcortree=2301 /SigmaFactorBS="tcttttttatgagaatgagtgagaaaaaGAGTGAAAacaaat ccaactaaTGTTAAATTTACATATATATgcatctatcaatctaattgacaattgtcat c" /listShort="S1531, htpG" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3957075..3957326) /gene="yxcA" /locus_tag="BSU_39830" /old_locus_tag="BSU39830" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_391862.1" /db_xref="EnsemblGenomes-Gn:BSU39830" /db_xref="EnsemblGenomes-Tr:CAB16019" /db_xref="GOA:P46332" /db_xref="SubtiList:BG11358" /db_xref="UniProtKB/Swiss-Prot:P46332" /translation="MKVQHKKELKFYCIVTIPSAFVVLTVISFLLQEITFPVTASAFL NASWHNLLFLIPFGLFFYPVHIWMKREFGRWNDTEKKRG*" gene complement(3957075..3957326) /gene="yxcA" /locus_tag="BSU_39830" /old_locus_tag="BSU39830" downshifts complement(3957093) /Source="Nicolas_upshifts" /id="D2058" /incds=0 /nref=11 /ntot=62 /MaxReadThrough="3.50049" /MaxDrop="5.56962" /score="-3.89567108" /energy="-6.7" /TU="U3133" /idTUdmin="U3133" /TUdmin="-66" /isTUend="FALSE" misc_feature complement(3957348..3957367) /Source="Nicolas_upshift_promotors" /id="U3133" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.928071928071928" /psig="0.995004995004995" /xcortree=2181 /SigmaFactorBS="gtcttcccgctatgtgcagtgataaacatgcgagaaaagaaa ggccagcaTATGTTAAGATGAATTAGAAattgttgggaggtttgtatgtttgaaggta c" /listShort="yxcA" /listLong="S1531, htpG" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(3957357) /Source="Nicolas_upshifts" /id="U3133" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.928071928071928" /psig="0.995004995004995" /xcortree=2181 /SigmaFactorBS="gtcttcccgctatgtgcagtgataaacatgcgagaaaagaaa ggccagcaTATGTTAAGATGAATTAGAAattgttgggaggtttgtatgtttgaaggta c" /listShort="yxcA" /listLong="S1531, htpG" promotor_-35 3957390..3957396 /Source="Nicolas_upshift_promotors" /id="U3134" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=245 /SigmaFactorBS="taattcatcttaacatatgctggcctttcttttctcgcaTGT TTATcactgcacatagcGGGAAGACAAATAGAAAAAggaggtctcgtatcatgggaag a" /listShort="yxbG" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3957410..3957428 /Source="Nicolas_upshift_promotors" /id="U3134" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=245 /SigmaFactorBS="taattcatcttaacatatgctggcctttcttttctcgcaTGT TTATcactgcacatagcGGGAAGACAAATAGAAAAAggaggtctcgtatcatgggaag a" /listShort="yxbG" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3957411 /Source="Nicolas_upshifts" /id="U3134" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=245 /SigmaFactorBS="taattcatcttaacatatgctggcctttcttttctcgcaTGT TTATcactgcacatagcGGGAAGACAAATAGAAAAAggaggtctcgtatcatgggaag a" /listShort="yxbG" /GFF_Attribute="listLong" CDS 3957443..3958264 /gene="yxbG" /locus_tag="BSU_39840" /old_locus_tag="BSU39840" /EC_number="1.-.-.-" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 10746760; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative oxidoreductase" /protein_id="NP_391863.2" /db_xref="EnsemblGenomes-Gn:BSU39840" /db_xref="EnsemblGenomes-Tr:CAB16020" /db_xref="GOA:P46331" /db_xref="InterPro:IPR002347" /db_xref="InterPro:IPR020904" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG11357" /db_xref="UniProtKB/Swiss-Prot:P46331" /translation="MGRLENKTAVITGAATGIGQATAEVFANEGARVIIGDINKDQME ETVDAIRKNGGQAESFHLDVSDENSVKAFADQIKDACGTIDILFNNAGVDQEGGKVHE YPVDLFDRIIAVDLRGTFLCSKYLIPLMLENGGSIINTSSMSGRAADLDRSGYNAAKG GITNLTKAMAIDYARNGIRVNSISPGTIETPLIDKLAGTKEQEMGEQFREANKWITPL GRLGQPKEMATVALFLASDDSSYVTGEDITADGGIMAYTWPGKMLIEEKWKEETK*" gene 3957443..3958264 /gene="yxbG" /locus_tag="BSU_39840" /old_locus_tag="BSU39840" downshifts 3958248 /Source="Nicolas_upshifts" /id="D2059" /incds=0 /nref=22 /ntot=67 /MaxReadThrough="2.87575" /MaxDrop="5.67438" /score="22.9485028" /energy="-10.5" /TU="U3134" /idTUdmin="U3134" /TUdmin="-221" /isTUend="FALSE" CDS complement(3958293..3959435) /gene="yxbF" /locus_tag="BSU_39850" /old_locus_tag="BSU39850" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 11160890; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative transcriptional regulator" /protein_id="NP_391864.1" /db_xref="EnsemblGenomes-Gn:BSU39850" /db_xref="EnsemblGenomes-Tr:CAB16021" /db_xref="GOA:P46330" /db_xref="InterPro:IPR001647" /db_xref="InterPro:IPR009057" /db_xref="SubtiList:BG11356" /db_xref="UniProtKB/Swiss-Prot:P46330" /translation="MPESAEAQVKEALLALLKDRDIQHITMKEIAEKAKVSRGSLYLY YEDKFSIIEDVIEDMKEGLGKALFDAFSHMDTLHLNKKRQTVHPTLSFVHEHRSFFSV MMNRGHFHRFFKDVFQQDVLLAPIHVNLTPIERDIYGHYRALYTYAIILYWLNEDAAA SPEAISQKVWELVSQKRFYWLFGKAVPGEREKEKQIDRRVVRTREALQKAFLDVLAEK QDYAGITISDITRKSNIRRATFYDHYANKEELLQTMIQRSCAEIIDHLTIASSPNEFS LKEAEKALAILLSALSNMPIVHFLNREWGVPHVIPDMFKALESFYLHQQTDIHAEKKL YAHYVSAMIIGLLLYRLDEGKAHPPEVLAREFLQFLDVKKYKVVLL*" gene complement(3958293..3959435) /gene="yxbF" /locus_tag="BSU_39850" /old_locus_tag="BSU39850" downshifts complement(3958303) /Source="Nicolas_upshifts" /id="D2060" /incds=0 /nref=10 /ntot=163 /MaxReadThrough="1.63217" /MaxDrop="3.79969" /score="-0.564494299" /energy="-10.5" /TU="NA" /idTUdmin="U3135" /TUdmin=0 /isTUend="TRUE" S_feature complement(3959436..3959535) /Source="Nicolas_S_feature" /locus_tag="new_4093838_4093937_c" /HighExp="H2O2, Diami, dia15, Paraq, G180, G135, G150, dia5, Oxctl, LBGexp" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.997" /TUlongSig="NA" /TUlongPSig="NA" /label="S1532" promotor_-10 complement(3959523..3959542) /Source="Nicolas_upshift_promotors" /id="U3135" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.926073926073926" /psig="0.997002997002997" /xcortree=1836 /SigmaFactorBS="tttacttgctgttccattgtaaaatccccctCATTTGCTttc ttcttttctcGGACCTATTATAAGGTGGTAccttttctgtaagaaagacaacggtgaa c" /listShort="S1532, yxbF" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3959534) /Source="Nicolas_upshifts" /id="U3135" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.926073926073926" /psig="0.997002997002997" /xcortree=1836 /SigmaFactorBS="tttacttgctgttccattgtaaaatccccctCATTTGCTttc ttcttttctcGGACCTATTATAAGGTGGTAccttttctgtaagaaagacaacggtgaa c" /listShort="S1532, yxbF" /GFF_Attribute="listLong" promotor_-35 complement(3959556..3959563) /Source="Nicolas_upshift_promotors" /id="U3135" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.926073926073926" /psig="0.997002997002997" /xcortree=1836 /SigmaFactorBS="tttacttgctgttccattgtaaaatccccctCATTTGCTttc ttcttttctcGGACCTATTATAAGGTGGTAccttttctgtaagaaagacaacggtgaa c" /listShort="S1532, yxbF" /GFF_Attribute="listLong" /label="promotor_-35" CDS 3959578..3960915 /gene="aldX" /locus_tag="BSU_39860" /old_locus_tag="BSU39860" /EC_number="1.2.1.3" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative aldehyde dehydrogenase" /protein_id="NP_391865.2" /db_xref="EnsemblGenomes-Gn:BSU39860" /db_xref="EnsemblGenomes-Tr:CAB16022" /db_xref="GOA:P46329" /db_xref="InterPro:IPR012394" /db_xref="InterPro:IPR015590" /db_xref="InterPro:IPR016160" /db_xref="InterPro:IPR016161" /db_xref="InterPro:IPR016162" /db_xref="InterPro:IPR029510" /db_xref="SubtiList:BG11355" /db_xref="UniProtKB/Swiss-Prot:P46329" /translation="MEQQVKDDIQRVFQLQKKQQKALRASTAEQRREKLQRFLDSVIA HEEEIIEAIRKDVRKPYHEVKKAEIEGTKKAIRDNMNNLEQWMAPKEVGSSLSPDANG ILMYEPKGVTLILGPWNYPFMLTMAPLAASLAAGNSAIVKLSDFTMNTSNIAAKVIRD AFDEKEVAIFEGEVEVATELLDQPFDHIFFTGSTNVGKIVMTAAAKHLASVTLELGGK SPTIIDSEYDLMDAAKKIAVGKFVNAGQTCIAPDYLFIKKDVQDRFAGILQTVVNAGF MEDDHTPDRSKFTQIVNDRNFNRVKDLFDDAIERGAEVVFGGVFDASDRTISPTVLKN VTPDMKIMQEEIFASILPMMNYEDIDEVIDYVNDRDKPLALYVFSKNQDLIDNVLQHT TSGNAAINDVVVHFSDVNLPFGGVNTSGIGSYHGVYGFKEFSHEKGVFIQAAE*" gene 3959578..3960915 /gene="aldX" /locus_tag="BSU_39860" /old_locus_tag="BSU39860" S_feature complement(3960320..3960920) /Source="Nicolas_S_feature" /locus_tag="new_4094722_4095322_c" /HighExp="T1.30H, T2.30H, T2.0H, T1.0H, T-2.40H, T3.0H, T3.30H, T0.0H, T-0.40H, T-3.40H" /AntisenseName="aldX" /AntisenseCor="-0.39894728806999702" /AntisenseRegPval="-11" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1533" CDS complement(3960954..3961433) /gene="yxbD" /locus_tag="BSU_39870" /old_locus_tag="BSU39870" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative N-acetyltransferase" /protein_id="NP_391866.2" /db_xref="EnsemblGenomes-Gn:BSU39870" /db_xref="EnsemblGenomes-Tr:CAB16023" /db_xref="GOA:P46328" /db_xref="InterPro:IPR000182" /db_xref="InterPro:IPR016181" /db_xref="SubtiList:BG11354" /db_xref="UniProtKB/Swiss-Prot:P46328" /translation="MNIIPTCQVPKDLVSAFFQKHWGSPQMVISSGIYNCDELDGYGM LNDDNQIVGLITYIFEEDACEIISLDSVIENKGIGTALLEKAEEACRERNIKQIKLIT TNDNIHALAFYQKRGYRLDRLFVNAVETARKMKPEIPLLADNKIPIRDELLLVKELQ* " gene complement(3960954..3961433) /gene="yxbD" /locus_tag="BSU_39870" /old_locus_tag="BSU39870" downshifts complement(3960965) /Source="Nicolas_upshifts" /id="D2061" /incds=0 /nref=1 /ntot=39 /MaxReadThrough="3.82941" /MaxDrop="2.52984" /score="-7.41869067" /energy="-10.9" /TU="U3136" /idTUdmin="U3136" /TUdmin="-616" /isTUend="FALSE" CDS complement(3961513..3962505) /gene="yxbC" /locus_tag="BSU_39880" /old_locus_tag="BSU39880" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_391867.1" /db_xref="EnsemblGenomes-Gn:BSU39880" /db_xref="EnsemblGenomes-Tr:CAB16024" /db_xref="GOA:P46327" /db_xref="InterPro:IPR003347" /db_xref="PDB:1VRB" /db_xref="SubtiList:BG11353" /db_xref="UniProtKB/Swiss-Prot:P46327" /translation="MSAVTESVLESIISPVTMSEFLEEYWPVKPLVARGEVERFTSIP GFEKVRTLENVLAIYNNPVMVVGDAVIEESEGITDRFLVSPAEALEWYEKGAALEFDF TDLFIPQVRRWIEKLKAELRLPAGTSSKAIVYAAKNGGGFKAHFDAYTNLIFQIQGEK TWKLAKNENVSNPMQHYDLSEAPYYPDDLQSYWKGDPPKEDLPDAEIVNLTPGTMLYL PRGLWHSTKSDQATLALNITFGQPAWLDLMLAALRKKLISDNRFRELAVNHQSLHESS KSELNGYLESLIQTLSENAETLTPEQIFQSQDSDFDPYQSTQLVFRQLLTSYKF*" gene complement(3961513..3962505) /gene="yxbC" /locus_tag="BSU_39880" /old_locus_tag="BSU39880" downshifts complement(3961537) /Source="Nicolas_upshifts" /id="D2062" /incds=0 /nref=5 /ntot=98 /MaxReadThrough="5.86537" /MaxDrop="5.28716" /score="-7.41869067" /energy="-10.9" /TU="U3136" /idTUdmin="U3136" /TUdmin="-1188" /isTUend="FALSE" downshifts 3962495 /Source="Nicolas_upshifts" /id="D2063" /incds=0 /nref=2 /ntot=56 /MaxReadThrough="1.15059" /MaxDrop="3.74519" /score="9.93493822" /energy="-12.4" /TU="NA" /idTUdmin="U3134" /TUdmin=4026 /isTUend="FALSE" promotor_-10 complement(3962528..3962547) /Source="Nicolas_upshift_promotors" /id="U3136" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.967032967032967" /psig=1 /xcortree=476 /SigmaFactorBS="acaactaaatattataatcctctgataattctgtcaaTATTT ACTtttagaaaaaaatgTTATATCTTTGTGGTGAAGTtactttttttgggagggataa t" /listShort="yxbC, yxbD, S1533" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3962546) /Source="Nicolas_upshifts" /id="U3136" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.967032967032967" /psig=1 /xcortree=476 /SigmaFactorBS="acaactaaatattataatcctctgataattctgtcaaTATTT ACTtttagaaaaaaatgTTATATCTTTGTGGTGAAGTtactttttttgggagggataa t" /listShort="yxbC, yxbD, S1533" /GFF_Attribute="listLong" promotor_-35 complement(3962562..3962569) /Source="Nicolas_upshift_promotors" /id="U3136" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.967032967032967" /psig=1 /xcortree=476 /SigmaFactorBS="acaactaaatattataatcctctgataattctgtcaaTATTT ACTtttagaaaaaaatgTTATATCTTTGTGGTGAAGTtactttttttgggagggataa t" /listShort="yxbC, yxbD, S1533" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 3962568..3962575 /Source="Nicolas_upshift_promotors" /id="U3137" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.99100899100899" /psig=1 /xcortree=477 /SigmaFactorBS="cttcaccacaaagatataacatttttttctaaaagtaaaTAT TGACAgaattatcagaggaTTATAATATTTAGTTGTGCGtgatagcctatttttttac a" /listShort="S1534, yxbB, aslA, yxnB, asnH, yxaM" /GFF_Attribute="listLong" /label="promotor_-35" S_feature 3962589..3963013 /Source="Nicolas_S_feature" /locus_tag="new_4096991_4097415" /HighExp="T2.0H, T5.0H, M9-stat, T3.0H, T1.30H, T1.0H, T3.30H, T2.30H, T4.0H, Pyr" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.998942" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1534" upshifts 3962589 /Source="Nicolas_upshifts" /id="U3137" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.99100899100899" /psig=1 /xcortree=477 /SigmaFactorBS="cttcaccacaaagatataacatttttttctaaaagtaaaTAT TGACAgaattatcagaggaTTATAATATTTAGTTGTGCGtgatagcctatttttttac a" /listShort="S1534, yxbB, aslA, yxnB, asnH, yxaM" /GFF_Attribute="listLong" promotor_-10 3962590..3962609 /Source="Nicolas_upshift_promotors" /id="U3137" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.99100899100899" /psig=1 /xcortree=477 /SigmaFactorBS="cttcaccacaaagatataacatttttttctaaaagtaaaTAT TGACAgaattatcagaggaTTATAATATTTAGTTGTGCGtgatagcctatttttttac a" /listShort="S1534, yxbB, aslA, yxnB, asnH, yxaM" /GFF_Attribute="listLong" /label="promotor_-10" misc_RNA 3962595..3963007 /gene="srlX" /locus_tag="BSU_misc_RNA_86" /product="putative small RNA or mRNA leader sequence" /experiment="publication(s) with functional evidences, PMID:20525796" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 20525796; Product type n: RNA" gene 3962595..3963007 /gene="srlX" /locus_tag="BSU_misc_RNA_86" upshifts complement(3962615) /Source="Nicolas_upshifts" /id="U3138" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.999000999001" /psig="0.000999000999001" /xcortree=719 /SigmaFactorBS="agacgaggtttcttataagcctttTTCATccttttcCCTCCT TCCTTGTAAaaaaataggctatcacgcacaactaaatattataatcctctgataattc t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 complement(3962625..3962639) /Source="Nicolas_upshift_promotors" /id="U3138" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.999000999001" /psig="0.000999000999001" /xcortree=719 /SigmaFactorBS="agacgaggtttcttataagcctttTTCATccttttcCCTCCT TCCTTGTAAaaaaataggctatcacgcacaactaaatattataatcctctgataattc t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 complement(3962647..3962651) /Source="Nicolas_upshift_promotors" /id="U3138" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.999000999001" /psig="0.000999000999001" /xcortree=719 /SigmaFactorBS="agacgaggtttcttataagcctttTTCATccttttcCCTCCT TCCTTGTAAaaaaataggctatcacgcacaactaaatattataatcctctgataattc t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 3962979 /Source="Nicolas_upshifts" /id="D2064" /incds=0 /nref=2 /ntot=9 /MaxReadThrough="8.39077" /MaxDrop="5.02548" /score="9.93493822" /energy="-12.4" /TU="U3137" /idTUdmin="U3134" /TUdmin=4510 /isTUend="FALSE" CDS 3963014..3963748 /gene="yxbB" /locus_tag="BSU_39890" /old_locus_tag="BSU39890" /EC_number="2.1.1.-" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15941984, 20185509; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative S-adenosylmethionine-dependent methyltransferase" /protein_id="NP_391868.1" /db_xref="EnsemblGenomes-Gn:BSU39890" /db_xref="EnsemblGenomes-Tr:CAB16025" /db_xref="GOA:P46326" /db_xref="InterPro:IPR013216" /db_xref="InterPro:IPR029063" /db_xref="SubtiList:BG11352" /db_xref="UniProtKB/Swiss-Prot:P46326" /translation="MITAEECRTYKEFVDLYQSYLYPLLGARLSRMYSPKNKVIIDMG TGPGYLSIQLAKRTNAHVHAVDINPAMHEIAQEEAKKSGVSSLISFDLEDVHHLSYAD QYADFIVSYSCLHHWEDVVKGLKECYRVLAPGGKIVILDTFNPQGSHLEIMRKQIKEP EYFRFVREAFEESYSFEDIHQFVQDAGIPNYSLETFHFLPEDFIESLDELEDAPLWEQ NDQSTDHEIESVTWMLTIEKEKEGAL*" gene 3963014..3963748 /gene="yxbB" /locus_tag="BSU_39890" /old_locus_tag="BSU39890" CDS 3963748..3964017 /gene="yxbA" /locus_tag="BSU_39900" /old_locus_tag="BSU39900" /function="16.13: Shape" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 17083466" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_391869.1" /db_xref="EnsemblGenomes-Gn:BSU39900" /db_xref="EnsemblGenomes-Tr:CAB16026" /db_xref="InterPro:IPR008792" /db_xref="SubtiList:BG11351" /db_xref="UniProtKB/Swiss-Prot:P46325" /translation="MINESTVLSKNPEMPSRKYLKSIIIEPGITLNEMASDIYNHIDG KVSIHDICSKIVNEYDVDYQTCLEDCMELFELLIDHEAIKVKQGA*" gene 3963748..3964017 /gene="yxbA" /locus_tag="BSU_39900" /old_locus_tag="BSU39900" CDS 3964021..3964503 /gene="yxnB" /locus_tag="BSU_39910" /old_locus_tag="BSU39910" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 20185509" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_391870.1" /db_xref="EnsemblGenomes-Gn:BSU39910" /db_xref="EnsemblGenomes-Tr:CAB16027" /db_xref="SubtiList:BG14166" /db_xref="UniProtKB/Swiss-Prot:O34704" /translation="MEKQKVLALPDDVHELSTHRSKSIVNYIITLLAFAKKQGLTHQD IVSWIHEQYEERGYYDEWRHINSQQPVGSFVELFIKGRRLLYDKIELFETEDKYVVNT HTWYEKEPSEAFFYFEIDPEEFSAYASILAIENAKRLGIKIDIVKETDVETAYIYKHQ *" gene 3964021..3964503 /gene="yxnB" /locus_tag="BSU_39910" /old_locus_tag="BSU39910" CDS 3964524..3966767 /gene="asnH" /locus_tag="BSU_39920" /old_locus_tag="BSU39920" /EC_number="6.3.5.4" /function="16.13: Shape" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:10498721, 17083466, 20185509" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10498721, 17083466, 20185509; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="asparagine synthetase (glutamine-hydrolyzing)" /protein_id="NP_391871.2" /db_xref="EnsemblGenomes-Gn:BSU39920" /db_xref="EnsemblGenomes-Tr:CAB16028" /db_xref="GOA:P42113" /db_xref="InterPro:IPR001962" /db_xref="InterPro:IPR006426" /db_xref="InterPro:IPR014729" /db_xref="InterPro:IPR017932" /db_xref="InterPro:IPR029055" /db_xref="InterPro:IPR033738" /db_xref="SubtiList:BG11116" /db_xref="UniProtKB/Swiss-Prot:P42113" /translation="MCGLAGIINLAAPRSQECTFHILKGMADAISYRGPDDEQYHIDS KVGFAFRRLSILDLVNGQQPFLNEDGSIVVMVNGEIYNYKELKASLHNHMFKTTSDCE VIVHLYEEKGIGFVDDIIGMFSIAIWDKNKNKVFLVRDRFGIKPLFYTELKHELIFAS EIKSLFSHPHCPRQFNWKEALSDIWLSGEAASNHKETTSFFVNIQNLDAGHYLEINLT TNERKTASYWSLQDILLRQGYRENLHPDDLIEGYRELLADSVHRCLQSDVEVGLFLSG GIDSAAVAHFAAEKQDLHTFTVLSQSTFTNEDAKYAHWLAKDLHLPNHQVLYQLGNDE LLQPESYKHLLWICETPFCGPEQLYKFHLHKYAKAIRPNLKVMLTGQGSDEFNGGYST TLSPAENPSWEGFIESVNTMEMNRLHRLQGNIFRVWEEHFGLSPINLSYLKSNDSSQA DPWQSYVLTKYRDLQMYNCWHEDRIAAANHIENRVPFLDHRLVEWVCGIPDGLRKDLL WDKSVLRKSLTNELHTSYTHRPKVPFFYGKDVRYTHKMMFHLLKKNNYQLIEEAFSHS DASSIIQVEHIHAIMTYLEDDPEFTNFEFLLRLVNMGLLSKMTKETPSVQLDITSHLE SITIKDWHSQEGDIASRLNISANKCEGQDILALNPGVTLLRPESDSEHCIYIAEEGFI QFIVSEEDVGAWLHILCDINGKDTLHTILDRHGVSLEEVAKYIQEAIEHNIILIKQKN LPEGAYR*" gene 3964524..3966767 /gene="asnH" /locus_tag="BSU_39920" /old_locus_tag="BSU39920" CDS 3966764..3967963 /gene="yxaM" /locus_tag="BSU_39930" /old_locus_tag="BSU39930" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15101989, 15849754, 16850406, 20185509; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative efflux transporter" /protein_id="NP_391872.2" /db_xref="EnsemblGenomes-Gn:BSU39930" /db_xref="EnsemblGenomes-Tr:CAB16029" /db_xref="GOA:P42112" /db_xref="InterPro:IPR011701" /db_xref="InterPro:IPR020846" /db_xref="InterPro:IPR036259" /db_xref="SubtiList:BG11115" /db_xref="UniProtKB/Swiss-Prot:P42112" /translation="MSIFYSFSALRGLAMGIFSPIWILYLISKDYDFLQIGLMGAVLE IAKLIFEVPSGVFADRYGIKISIASSFFFSILTWAFFPFIDSAAICILAMIIWALSDS LISGSFETWMSRVAGEDRFGKEMMKNTQLLITFLIIGSIASGYLYSLNIYFPFLLVMV IYLLLFIWMSVFIKVPSVSETNHGDQNQHDSIKIIKESLKIIFNKKRVLLIVIAGFFT ATAYDTISRYWQPFLSDLGFSEKSLGYIFALGGFTALVLLTLTIRFEKKIEKNPYLAL TSLDSMGMVMTFLLSRAFRPLGIPCTAFLLAIEDIHHPIVTSYLNKFFPDSYKNTLFS LNSGVGAIGEILSGVIFGIISAAFGLSAMFVVVAVFLLIPIILYTIVPKIKDNDMKVQ IEKSQQV*" gene 3966764..3967963 /gene="yxaM" /locus_tag="BSU_39930" /old_locus_tag="BSU39930" promotor_-10 complement(3967719..3967737) /Source="Nicolas_upshift_promotors" /id="U3139" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=266 /SigmaFactorBS="aagaatttctccaattgctcctacccctgagtttaacgagaa aAGTGTGTtcttgtatgaatcgGGGAAAAACTTATTTAAGTaacttgttacgatcgga t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3967741) /Source="Nicolas_upshifts" /id="U3139" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=266 /SigmaFactorBS="aagaatttctccaattgctcctacccctgagtttaacgagaa aAGTGTGTtcttgtatgaatcgGGGAAAAACTTATTTAAGTaacttgttacgatcgga t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(3967752..3967758) /Source="Nicolas_upshift_promotors" /id="U3139" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=266 /SigmaFactorBS="aagaatttctccaattgctcctacccctgagtttaacgagaa aAGTGTGTtcttgtatgaatcgGGGAAAAACTTATTTAAGTaacttgttacgatcgga t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 3967954 /Source="Nicolas_upshifts" /id="D2065" /incds=0 /nref=71 /ntot=174 /MaxReadThrough="3.22879" /MaxDrop="5.42242" /score="-6.94914943" /energy="-8.5" /TU="U3137" /idTUdmin="U3137" /TUdmin="-85" /isTUend="FALSE" downshifts complement(3968027) /Source="Nicolas_upshifts" /id="D2066" /incds=0 /nref=156 /ntot=227 /MaxReadThrough="3.53794" /MaxDrop="6.77896" /score="7.32872401" /energy="-16.9" /TU="U3140" /idTUdmin="U3141" /TUdmin=0 /isTUend="TRUE" CDS complement(3968027..3969259) /gene="yxaL" /locus_tag="BSU_39940" /old_locus_tag="BSU39940" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 12073041, 15743949, 17060472, 18165306, 22720735, 26060272; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="membrane associated protein kinase with beta-propeller domain" /protein_id="NP_391873.2" /db_xref="EnsemblGenomes-Gn:BSU39940" /db_xref="EnsemblGenomes-Tr:CAB16030" /db_xref="GOA:P42111" /db_xref="InterPro:IPR002372" /db_xref="InterPro:IPR011047" /db_xref="InterPro:IPR018391" /db_xref="SubtiList:BG11114" /db_xref="UniProtKB/Swiss-Prot:P42111" /translation="MVKSFRMKALIAGAAVAAAVSAGAVSDVPAAKVLQPTAAYAAET VFSQNNGASGFLPGRYDVQAMAPAMFNWSRESRFAGNTDGTLKWQNDIRTTPQNGAGA VIDGDGTVYLHSRDGEMKAFNPDGSVKWVTGNLGKTYTQSPVLGTNGVIYLASYDKKI YFIDKETGEILTTVPLSGGPSSETVIGSDGTLYFSTLDNYVHAIKPTSKSTWTERWKL KTNGVVSSVPVLAKNGTVYVGTYNYVFYAINSGTGQVKWSRTTSNAFKGYPVIDKDGN IYAGNQDGQLYAYTSTGSLKWTFPLNGFSSSSPAIDHNGNIYIGSGSGELFSISKNGD MNWSFYTDGPVRTAPLIDAKGTVYFGSDDMKVYAADANGNELWSYQTDSNVVSSPQLA EDGTLYIGSYTKLMAFGK*" gene complement(3968027..3969259) /gene="yxaL" /locus_tag="BSU_39940" /old_locus_tag="BSU39940" promotor_-10 complement(3969291..3969310) /Source="Nicolas_upshift_promotors" /id="U3140" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.417582417582418" /psig="0.999000999001" /xcortree=1611 /SigmaFactorBS="atagttttctagtttgtgatgtttttgtgaaataGATTTAta aaatggatgaaTATGTTATGATGGTCACAAAttagaagttacatataatgggggtctc a" /listShort="yxaL" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3969303) /Source="Nicolas_upshifts" /id="U3140" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.417582417582418" /psig="0.999000999001" /xcortree=1611 /SigmaFactorBS="atagttttctagtttgtgatgtttttgtgaaataGATTTAta aaatggatgaaTATGTTATGATGGTCACAAAttagaagttacatataatgggggtctc a" /listShort="yxaL" /GFF_Attribute="listLong" promotor_-35 complement(3969324..3969329) /Source="Nicolas_upshift_promotors" /id="U3140" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.417582417582418" /psig="0.999000999001" /xcortree=1611 /SigmaFactorBS="atagttttctagtttgtgatgtttttgtgaaataGATTTAta aaatggatgaaTATGTTATGATGGTCACAAAttagaagttacatataatgggggtctc a" /listShort="yxaL" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3969360..3969785) /gene="yxaJ" /locus_tag="BSU_39950" /old_locus_tag="BSU39950" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15743949, 15849754, 16850406, 27902860; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative integral membrane protein of unknown function" /protein_id="NP_391875.2" /db_xref="EnsemblGenomes-Gn:BSU39950" /db_xref="EnsemblGenomes-Tr:CAB16032" /db_xref="GOA:P42109" /db_xref="InterPro:IPR020204" /db_xref="SubtiList:BG11112" /db_xref="UniProtKB/Swiss-Prot:P42109" /translation="MSKKNSVAIMTTISAFLFCAVIVAASLSPLAGTGAAANQFNSAG MWSAVGMILVLYFIPFLVYMLGVDAMRYVMAVLCGFGLLIHLSSAGFILMFSFFSDHL LSEVIFVLGVSLAAAAVNVIWFVAAFRSGAEKTSVNTLT*" gene complement(3969360..3969785) /gene="yxaJ" /locus_tag="BSU_39950" /old_locus_tag="BSU39950" promotor_-10 complement(3969813..3969832) /Source="Nicolas_upshift_promotors" /id="U3141" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.452547452547453" /psig=1 /xcortree=2293 /SigmaFactorBS="catttgtgtatgtattctggaattttttaaaaatatAATGAA TataacattcaacTTACTTATAATAAAAAAGGTtaatatttctattaaaggaggagtt t" /listShort="yxaJ, yxaL" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3969827) /Source="Nicolas_upshifts" /id="U3141" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.452547452547453" /psig=1 /xcortree=2293 /SigmaFactorBS="catttgtgtatgtattctggaattttttaaaaatatAATGAA TataacattcaacTTACTTATAATAAAAAAGGTtaatatttctattaaaggaggagtt t" /listShort="yxaJ, yxaL" /GFF_Attribute="listLong" promotor_-35 complement(3969845..3969851) /Source="Nicolas_upshift_promotors" /id="U3141" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.452547452547453" /psig=1 /xcortree=2293 /SigmaFactorBS="catttgtgtatgtattctggaattttttaaaaatatAATGAA TataacattcaacTTACTTATAATAAAAAAGGTtaatatttctattaaaggaggagtt t" /listShort="yxaJ, yxaL" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 3969977..3969984 /Source="Nicolas_upshift_promotors" /id="U3142" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.526473526473527" /psig="0.995004995004995" /xcortree=2320 /SigmaFactorBS="aagactcatttttctgtaatatcaggattttatcaccatacc aTATTGCATgtacatgtttttcaAAGTATACTATTCCAGATTAattcagaggagagag a" /listShort="yxaI, S1535" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 3969994 /Source="Nicolas_upshifts" /id="U3142" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.526473526473527" /psig="0.995004995004995" /xcortree=2320 /SigmaFactorBS="aagactcatttttctgtaatatcaggattttatcaccatacc aTATTGCATgtacatgtttttcaAAGTATACTATTCCAGATTAattcagaggagagag a" /listShort="yxaI, S1535" /GFF_Attribute="listLong" promotor_-10 3969999..3970018 /Source="Nicolas_upshift_promotors" /id="U3142" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.526473526473527" /psig="0.995004995004995" /xcortree=2320 /SigmaFactorBS="aagactcatttttctgtaatatcaggattttatcaccatacc aTATTGCATgtacatgtttttcaAAGTATACTATTCCAGATTAattcagaggagagag a" /listShort="yxaI, S1535" /GFF_Attribute="listLong" /label="promotor_-10" CDS 3970042..3970497 /gene="yxaI" /locus_tag="BSU_39960" /old_locus_tag="BSU39960" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative integral membrane protein of unknown function" /protein_id="NP_391876.1" /db_xref="EnsemblGenomes-Gn:BSU39960" /db_xref="EnsemblGenomes-Tr:CAB16033" /db_xref="GOA:P42108" /db_xref="InterPro:IPR010432" /db_xref="SubtiList:BG11111" /db_xref="UniProtKB/Swiss-Prot:P42108" /translation="MEKPAGFWIRFLAYFIDGIIVSVPSYIILFIINSVFVAGAVATN PYMTEEEYLVKYMTLAFLPTMLIMIVISVLYYGLLTASKMQGTLGKKILGLKVVNEQG ERVSVGQGIGRYFAYILSGIIFYIGFIMIAFGEKKGLHDIICKTRVVYK*" gene 3970042..3970497 /gene="yxaI" /locus_tag="BSU_39960" /old_locus_tag="BSU39960" downshifts 3970435 /Source="Nicolas_upshifts" /id="D2067" /incds=1 /nref=58 /ntot=234 /MaxReadThrough="3.24719" /MaxDrop="5.4441" /score="18.1083522" /energy="-13.4" /TU="U3142" /idTUdmin="U3142" /TUdmin="-637" /isTUend="FALSE" S_feature 3970498..3971111 /Source="Nicolas_S_feature" /locus_tag="new_4104900_4105513" /HighExp="LPh, HPh, MG 60, BMM, MG t5, G180, MG 45, G150, MG-0.2, MG 10" /AntisenseName="yxaH" /AntisenseCor="0.37646026982403002" /AntisenseRegPval="-9.8000000000000007" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.995" /TUlongSig="NA" /TUlongPSig="NA" /label="S1535" CDS complement(3970527..3971735) /gene="yxaH" /locus_tag="BSU_39970" /old_locus_tag="BSU39970" /experiment="publication(s) with functional evidences, PMID:15317768, 15849754, 16850406, 21737930" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15317768, 15849754, 16850406, 21737930; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="integral inner membrane protein involved in response to flavonoids" /protein_id="NP_391877.2" /db_xref="EnsemblGenomes-Gn:BSU39970" /db_xref="EnsemblGenomes-Tr:CAB16034" /db_xref="GOA:P42107" /db_xref="InterPro:IPR007349" /db_xref="SubtiList:BG11110" /db_xref="UniProtKB/Swiss-Prot:P42107" /translation="MSSLQPTLTNERIGVLDVLRGMAIFGILFVNLAHFSYPDMYLSM LGKENFFMDKWSEADFAAADILKFFIQTKCILLFSFLFGFGMVVMMERAENKGKRFVP LYVRRLMALLLFGTIHAFLIWDGDILTEYALLGFVLLLFRKAKPKTLLIWAVSLYLLF SIPFMLTSFDQSNGQEWVQAVTQQAKQAIHVYGSGSLKDIAEQRIHDRLVYMSSNGML TYNPLNYFFASIPYFSMFLLGAAAAKSRYLHEPEKHRKGLKRLWMAGLVIGIGAQVLY SVTDKEICLLIGAPFLMFFYVTTVVYLYHKTRVRTVLQSFSAVGRMAFTNYLMQSIVC TWIFYHYGLGLYGKVYPAAGVLITIAVCAVQMVFSHLWLRVFRMGPFEWLWRSATYLS WQPIAKKTKV*" gene complement(3970527..3971735) /gene="yxaH" /locus_tag="BSU_39970" /old_locus_tag="BSU39970" downshifts complement(3970554) /Source="Nicolas_upshifts" /id="D2068" /incds=0 /nref=14 /ntot=66 /MaxReadThrough="0.30987" /MaxDrop="3.782" /score="34.1593124" /energy="-16.2" /TU="NA" /idTUdmin="U3143" /TUdmin=286 /isTUend="FALSE" S_feature complement(3971736..3971842) /Source="Nicolas_S_feature" /locus_tag="new_4106138_4106244_c" /HighExp="T-5.40H, T-4.40H, SMMPr, T-2.40H, T-3.40H, T-1.40H, Sw, T0.0H, Pyr, T-0.40H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.995" /TUlongSig="NA" /TUlongPSig="NA" /label="S1536" CDS complement(3971843..3972856) /gene="qdoI" /locus_tag="BSU_39980" /old_locus_tag="BSU39980" /EC_number="1.13.11.24" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:14697267, 15317768, 15628860, 17483215, 14741339, 15039076, 20460727, 21737930" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 14697267, 15317768, 15628860, 17483215, 14741339, 15039076, 20460727, 21737930; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="quercetin dioxygenase" /protein_id="NP_391878.2" /db_xref="EnsemblGenomes-Gn:BSU39980" /db_xref="EnsemblGenomes-Tr:CAB16035" /db_xref="GOA:P42106" /db_xref="InterPro:IPR011051" /db_xref="InterPro:IPR013096" /db_xref="InterPro:IPR014710" /db_xref="PDB:1Y3T" /db_xref="PDB:2H0V" /db_xref="SubtiList:BG11109" /db_xref="UniProtKB/Swiss-Prot:P42106" /translation="MKTLCTHSLPKEKMPYLLRSGEGERYLFGRQVATVMANGRSTGD LFEIVLLSGGKGDAFPLHVHKDTHEGILVLDGKLELTLDGERYLLISGDYANIPAGTP HSYRMQSHRTRLVSYTMKGNVAHLYSVIGNPYDHAEHPPYASEEVSNERFAEAAAVAD IVFLDEAKPACSAKLAELTELPDGAVPYVLESGEGDRLLTGDQLHRIVAAQKNTDGQF IVVSSEGPKGDRIVDHYHEYHTETFYCLEGQMTMWTDGQEIQLNPGDFLHVPANTVHS YRLDSHYTKMVGVLVPGLFEPFFRTLGDPYEGHIFPCEPQALRFDRILQNIEALDLKV MKP*" gene complement(3971843..3972856) /gene="qdoI" /locus_tag="BSU_39980" /old_locus_tag="BSU39980" S_feature complement(3972857..3972930) /Source="Nicolas_S_feature" /locus_tag="new_4107259_4107332_c" /HighExp="T-3.40H, T-5.40H, T-1.40H, T-2.40H, T-4.40H, T-0.40H, T0.0H, Pyr, SMMPr, GM-0.2" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.995" /TUlongSig="NA" /TUlongPSig="NA" /label="S1537" promotor_-10 complement(3972915..3972934) /Source="Nicolas_upshift_promotors" /id="U3143" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.622377622377622" /psig="0.995004995004995" /xcortree=2866 /SigmaFactorBS="ttgccgaacaaataccagtgctggtgagaaaaaaagGGTAGC ATtttgttatccttTCTCCTACAATTATATAGAAcggtctagacaaatgaatgataat a" /listShort="S1537, qodI, S1536, yxaH" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3972930) /Source="Nicolas_upshifts" /id="U3143" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.622377622377622" /psig="0.995004995004995" /xcortree=2866 /SigmaFactorBS="ttgccgaacaaataccagtgctggtgagaaaaaaagGGTAGC ATtttgttatccttTCTCCTACAATTATATAGAAcggtctagacaaatgaatgataat a" /listShort="S1537, qodI, S1536, yxaH" /GFF_Attribute="listLong" promotor_-35 complement(3972947..3972954) /Source="Nicolas_upshift_promotors" /id="U3143" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.622377622377622" /psig="0.995004995004995" /xcortree=2866 /SigmaFactorBS="ttgccgaacaaataccagtgctggtgagaaaaaaagGGTAGC ATtttgttatccttTCTCCTACAATTATATAGAAcggtctagacaaatgaatgataat a" /listShort="S1537, qodI, S1536, yxaH" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3972950..3973525) /gene="qdoR" /locus_tag="BSU_39990" /old_locus_tag="BSU39990" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:17483215, 21737930" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 17483215, 21737930; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator of qdoI" /protein_id="NP_391879.2" /db_xref="EnsemblGenomes-Gn:BSU39990" /db_xref="EnsemblGenomes-Tr:CAB16036" /db_xref="GOA:P42105" /db_xref="InterPro:IPR001647" /db_xref="InterPro:IPR009057" /db_xref="InterPro:IPR036271" /db_xref="PDB:1SGM" /db_xref="SubtiList:BG11108" /db_xref="UniProtKB/Swiss-Prot:P42105" /translation="MTSRGDSREKILHTASRLFQLQGYHATGLNQIVKESGAPKGSLY HFFPNGKEELAIEAVTYTGKIVEHLIQQSMDESSDPVEAIQLFIKKTASQFDNTESIK GIPVGLLASETALISEPLRTVCMKVFKSWEAVFARKLMENGFAEEEANQLGTLINSMI EGGIMLSLTNKDKTPLLLIAEQIPVLVRKKG*" gene complement(3972950..3973525) /gene="qdoR" /locus_tag="BSU_39990" /old_locus_tag="BSU39990" downshifts complement(3972974) /Source="Nicolas_upshifts" /id="D2069" /incds=0 /nref=1 /ntot=19 /MaxReadThrough="1.66581" /MaxDrop="2.62803" /score="-2.51956315" /energy="-8.8" /TU="NA" /idTUdmin="U3144" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(3973554..3973573) /Source="Nicolas_upshift_promotors" /id="U3144" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.85914085914086" /psig="0.999000999001" /xcortree=2479 /SigmaFactorBS="tgtacattaccccatccggaagggtcttaccccTTTTGACAa tcacagggttcttTTTTATATTATATAAGTCGCtctaccatacctaggagggaatgtt t" /listShort="yxaF" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3973568) /Source="Nicolas_upshifts" /id="U3144" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.85914085914086" /psig="0.999000999001" /xcortree=2479 /SigmaFactorBS="tgtacattaccccatccggaagggtcttaccccTTTTGACAa tcacagggttcttTTTTATATTATATAAGTCGCtctaccatacctaggagggaatgtt t" /listShort="yxaF" /GFF_Attribute="listLong" promotor_-35 complement(3973588..3973595) /Source="Nicolas_upshift_promotors" /id="U3144" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.85914085914086" /psig="0.999000999001" /xcortree=2479 /SigmaFactorBS="tgtacattaccccatccggaagggtcttaccccTTTTGACAa tcacagggttcttTTTTATATTATATAAGTCGCtctaccatacctaggagggaatgtt t" /listShort="yxaF" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 3973596..3973602 /Source="Nicolas_upshift_promotors" /id="U3145" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=252 /SigmaFactorBS="taatataaaaaagaaccctgtgattgtcaaaaGGGGTAAgac ccttccggatgGGGTAATGTACAAAAACAGcgtctaggagggatctctcaatgacaat c" /listShort="yxnA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3973617..3973635 /Source="Nicolas_upshift_promotors" /id="U3145" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=252 /SigmaFactorBS="taatataaaaaagaaccctgtgattgtcaaaaGGGGTAAgac ccttccggatgGGGTAATGTACAAAAACAGcgtctaggagggatctctcaatgacaat c" /listShort="yxnA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3973624 /Source="Nicolas_upshifts" /id="U3145" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=252 /SigmaFactorBS="taatataaaaaagaaccctgtgattgtcaaaaGGGGTAAgac ccttccggatgGGGTAATGTACAAAAACAGcgtctaggagggatctctcaatgacaat c" /listShort="yxnA" /GFF_Attribute="listLong" CDS 3973656..3974726 /gene="yxnA" /locus_tag="BSU_40000" /old_locus_tag="BSU40000" /EC_number="1.-.-.-" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative oxidoreductase" /protein_id="NP_391880.2" /db_xref="EnsemblGenomes-Gn:BSU40000" /db_xref="EnsemblGenomes-Tr:CAB16037" /db_xref="GOA:O32291" /db_xref="InterPro:IPR002347" /db_xref="InterPro:IPR020904" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG14165" /db_xref="UniProtKB/Swiss-Prot:O32291" /translation="MTIDHSVTNTEQLEQQNPAIKTKLKLKKLKDQVIVITGASSGIG LVTARMAAEKGAKVVAAARNEEALKELTDELKEKGHDAIWVKADVGKEEDVNRIAETA ISTFGRFDTWVNNAAVSTFGHAMDVTVEDMKRMFDTNFWGPVYGTRAAVKHYTGRGVP GALINVGSLFGDRGTVIQSTYASAKFALHGWTESIRMELEKEQAPVSVTLIHPGRIDT PYNEHAHSYLDKQPAHYRSMIYPPEAVAEAILFAAEHPKRDMYIGSQAKAIAMLGALF PRLTDRLMEKIMYHSQHAERPSNPREESALYDAGCGMHDRGTNKGWMRSRSYYTKATK RPIVSAAVVAGLVAWAAAKRCR*" gene 3973656..3974726 /gene="yxnA" /locus_tag="BSU_40000" /old_locus_tag="BSU40000" downshifts 3974724 /Source="Nicolas_upshifts" /id="D2070" /incds=0 /nref=7 /ntot=44 /MaxReadThrough="2.68466" /MaxDrop="3.96227" /score="-3.48213422" /energy="-11.2" /TU="NA" /idTUdmin="U3145" /TUdmin=0 /isTUend="TRUE" CDS complement(3974783..3975214) /gene="yxaD" /locus_tag="BSU_40010" /old_locus_tag="BSU40010" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative transcriptional regulator (MarR family)" /protein_id="NP_391881.1" /db_xref="EnsemblGenomes-Gn:BSU40010" /db_xref="EnsemblGenomes-Tr:CAB16038" /db_xref="GOA:P42103" /db_xref="InterPro:IPR000835" /db_xref="InterPro:IPR023187" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG11106" /db_xref="UniProtKB/Swiss-Prot:P42103" /translation="MQNQNPVELIEYELTTFIRRAVYLDQSEKRTGNLERSSYLLLRQ LDEFGPARVKELAESFKLDISTLSRQAAALEAKELIYRFSDPSDGRVSLFTITKLGKQ LLKADQQKRLERYEQMLKEWSTQEKEMFGELLQRMNKAFID*" gene complement(3974783..3975214) /gene="yxaD" /locus_tag="BSU_40010" /old_locus_tag="BSU40010" promotor_-35 3975244..3975251 /Source="Nicolas_upshift_promotors" /id="U3146" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.96903096903097" /psig=1 /xcortree=2436 /SigmaFactorBS="atcgctctcgctccctattccaatctccggCATTGACAacat catatatacTTGTATAATACAAATGTACAttaactgaataaatacaagtcgttatatg a" /listShort="S1538, yxzK, yxaC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3975265..3975284 /Source="Nicolas_upshift_promotors" /id="U3146" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.96903096903097" /psig=1 /xcortree=2436 /SigmaFactorBS="atcgctctcgctccctattccaatctccggCATTGACAacat catatatacTTGTATAATACAAATGTACAttaactgaataaatacaagtcgttatatg a" /listShort="S1538, yxzK, yxaC" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 3975274..3975440 /Source="Nicolas_S_feature" /locus_tag="new_4109676_4109842" /HighExp="LBGstat, Cold, Heat, Salt, Etha, H2O2, G180, LBGtran, GM 150, MG 15" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1538" upshifts 3975274 /Source="Nicolas_upshifts" /id="U3146" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.96903096903097" /psig=1 /xcortree=2436 /SigmaFactorBS="atcgctctcgctccctattccaatctccggCATTGACAacat catatatacTTGTATAATACAAATGTACAttaactgaataaatacaagtcgttatatg a" /listShort="S1538, yxzK, yxaC" /GFF_Attribute="listLong" promotor_-10 complement(3975326..3975345) /Source="Nicolas_upshift_promotors" /id="U3147" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.85014985014985" /psig="0.999000999001" /xcortree=2442 /SigmaFactorBS="cctttctggtgcttgcttctaggatggttctgaggaatcGCT TTACTttctttttatatgaTTGTACTATACAAGTATAATaattgatttagtcatataa c" /listShort="yxaD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3975346) /Source="Nicolas_upshifts" /id="U3147" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.85014985014985" /psig="0.999000999001" /xcortree=2442 /SigmaFactorBS="cctttctggtgcttgcttctaggatggttctgaggaatcGCT TTACTttctttttatatgaTTGTACTATACAAGTATAATaattgatttagtcatataa c" /listShort="yxaD" /GFF_Attribute="listLong" promotor_-35 complement(3975360..3975367) /Source="Nicolas_upshift_promotors" /id="U3147" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.85014985014985" /psig="0.999000999001" /xcortree=2442 /SigmaFactorBS="cctttctggtgcttgcttctaggatggttctgaggaatcGCT TTACTttctttttatatgaTTGTACTATACAAGTATAATaattgatttagtcatataa c" /listShort="yxaD" /GFF_Attribute="listLong" /label="promotor_-35" CDS 3975441..3975845 /gene="yxzK" /locus_tag="BSU_40021" /old_locus_tag="BSU40021" /function="16.13: Shape" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative integral inner membrane protein involved in export murein hydrolases" /protein_id="YP_003097798.1" /db_xref="EnsemblGenomes-Gn:BSU40021" /db_xref="EnsemblGenomes-Tr:CAX52713" /db_xref="GOA:C0H3T7" /db_xref="InterPro:IPR005538" /db_xref="InterPro:IPR036640" /db_xref="UniProtKB/Swiss-Prot:C0H3T7" /translation="MKVIRIILQVLILYVFFMIGEAIQHLFHLPVSGSIVGLVLLLIC LGLRIVPVSIIEDGAGFLLSFLPLLFIPAMTGVINYPSLISFNGLMLLITVVLSTIVT IIAAGFASQLLEKKAKKREEKEKCSKHVSRSL*" gene 3975441..3975845 /gene="yxzK" /locus_tag="BSU_40021" /old_locus_tag="BSU40021" S_feature complement(3975462..3976514) /Source="Nicolas_S_feature" /locus_tag="new_4109864_4110916_c" /HighExp="Etha, C30, H2O2, Salt, Paraq, GM 120, Diami, Oxctl, G180, Sw" /AntisenseName="yxaC" /AntisenseCor="0.145103505386703" /AntisenseRegPval="-1.8" /CDS_PredictionProba="NA" /TUshortSig="SigB" /TUshortPSig="0.987" /TUlongSig="NA" /TUlongPSig="NA" /label="S1539" CDS 3975815..3976507 /gene="yxaC" /locus_tag="BSU_40022" /old_locus_tag="BSU40022" /function="16.13: Shape" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15126464, 15849754, 16850406, 17452642, 26060272; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative murein hydrolase export regulator" /protein_id="NP_391882.3" /db_xref="EnsemblGenomes-Gn:BSU40022" /db_xref="EnsemblGenomes-Tr:CAB16039" /db_xref="GOA:P42102" /db_xref="InterPro:IPR007300" /db_xref="SubtiList:BG11105" /db_xref="UniProtKB/Swiss-Prot:P42102" /translation="MQQACIAIIIILLTVAAYLAMVKLYKRFPLPFLIPVLTTTILIV AALMMFHVSYEGYMIGGKWINSLLGPAVVALAYPLYKQWHIIVKHCVPILGGVLVGLC MGMISGLIFAEAFGIDHDLLLSILPKSITTPVAIQIAAGLGGVPSMTVVFVMIAGFSG VILGPLFLKWLRIRSSLGQGIALGSASHALGTSKALEYGELAVSMSSVSMTLCAVLGS FFGPLVVWLFHI*" gene 3975815..3976507 /gene="yxaC" /locus_tag="BSU_40022" /old_locus_tag="BSU40022" CDS complement(3976547..3977578) /gene="yxaB" /locus_tag="BSU_40030" /old_locus_tag="BSU40030" /EC_number="2.-.-.-" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 9298659, 18326573; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative exopolysaccharide pyruvyl transferase (biofilm formation)" /protein_id="NP_391883.3" /db_xref="EnsemblGenomes-Gn:BSU40030" /db_xref="EnsemblGenomes-Tr:CAB16040" /db_xref="GOA:P42101" /db_xref="InterPro:IPR007345" /db_xref="SubtiList:BG11104" /db_xref="UniProtKB/Swiss-Prot:P42101" /translation="MTVQEIKGKKLVKGIAPNVEPEALLNDKRKVFLFGSPSYTNIGD QAIAYAEEKFIKNHFPYYEYIEIMDYATDEGIELVKEIIREDDIVCFTGGGNLGNLYL DIEEDRRKVFSAFKDYKSISLPQSVYFEDTEEGQKEKKKTQDAYHQNTNLTIAARETQ TLDVVKETFNSNVIFTPDMVLSLDIVPRELERDGVLFILRADKEKVTDEDFISQMKQW AEKTTYTERTDTVLDTVDTIDYADREKHFMEMLDRIGSSKLVITDRLHAMIFSIITKT PCLVFGNSYGKAKHSYRDWLESLNFIEYTDKNDVEELERMIDRLLQAEPNDVDLSKDF QPLIDFFAS*" gene complement(3976547..3977578) /gene="yxaB" /locus_tag="BSU_40030" /old_locus_tag="BSU40030" downshifts complement(3976559) /Source="Nicolas_upshifts" /id="D2071" /incds=0 /nref=5 /ntot=94 /MaxReadThrough="6.52386" /MaxDrop="4.6522" /score="17.8326496" /energy="-15.3" /TU="U3149" /idTUdmin="U3150" /TUdmin=220 /isTUend="FALSE" promotor_-35 3977545..3977548 /Source="Nicolas_upshift_promotors" /id="U3148" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.618381618381618" /psig="0.996003996003996" /xcortree=1822 /SigmaFactorBS="atttaacagagcttccggctccacatttggcgcaatgccttt taCTAGttttttgcctttgattTCTTGTACAGTCATATCTGCgtcctccttctgggat g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 3977561 /Source="Nicolas_upshifts" /id="U3148" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.618381618381618" /psig="0.996003996003996" /xcortree=1822 /SigmaFactorBS="atttaacagagcttccggctccacatttggcgcaatgccttt taCTAGttttttgcctttgattTCTTGTACAGTCATATCTGCgtcctccttctgggat g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 3977565..3977584 /Source="Nicolas_upshift_promotors" /id="U3148" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.618381618381618" /psig="0.996003996003996" /xcortree=1822 /SigmaFactorBS="atttaacagagcttccggctccacatttggcgcaatgccttt taCTAGttttttgcctttgattTCTTGTACAGTCATATCTGCgtcctccttctgggat g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-10 complement(3977615..3977633) /Source="Nicolas_upshift_promotors" /id="U3149" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.987012987012987" /psig="0.987012987012987" /xcortree=258 /SigmaFactorBS="cgaaaacgatgtttctgatatagccgatgcacatgccaaTGC ATAGccatccttctttttGGGTAGAGACAGTTAACACacaatgaggaattcatcccag a" /listShort="yxaB, S1539" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3977633) /Source="Nicolas_upshifts" /id="U3149" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.987012987012987" /psig="0.987012987012987" /xcortree=258 /SigmaFactorBS="cgaaaacgatgtttctgatatagccgatgcacatgccaaTGC ATAGccatccttctttttGGGTAGAGACAGTTAACACacaatgaggaattcatcccag a" /listShort="yxaB, S1539" /GFF_Attribute="listLong" promotor_-35 complement(3977648..3977654) /Source="Nicolas_upshift_promotors" /id="U3149" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.987012987012987" /psig="0.987012987012987" /xcortree=258 /SigmaFactorBS="cgaaaacgatgtttctgatatagccgatgcacatgccaaTGC ATAGccatccttctttttGGGTAGAGACAGTTAACACacaatgaggaattcatcccag a" /listShort="yxaB, S1539" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3977671..3978819) /gene="glxK" /locus_tag="BSU_40040" /old_locus_tag="BSU40040" /EC_number="2.7.1.31" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 15771780, 18326573; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="D-glycerate kinase" /protein_id="NP_391884.2" /db_xref="EnsemblGenomes-Gn:BSU40040" /db_xref="EnsemblGenomes-Tr:CAB16041" /db_xref="GOA:P42100" /db_xref="InterPro:IPR004381" /db_xref="InterPro:IPR018193" /db_xref="InterPro:IPR036129" /db_xref="SubtiList:BG11103" /db_xref="UniProtKB/Swiss-Prot:P42100" /translation="MKIIIAPDSFKESLSALEAAEAIERGFKSVFPGADYRKLPVADG GEGTVQSLVDATNGRIIEQVVTGPLGEPVRAFFGMMGDGRTAVIEMAAASGLHLVPVD KRNPLITTTRGTGELIGAALDAGAERLIIGIGGSATNDGGAGMIQALGGRLLDNSGSE IGPGGGALSQLASIDVSGLDSRLRNVKLEVACDVDNPLTGPKGATAVFGPQKGATADM LDVLDQNVSHFADMAEKALGSTFRDTEGAGAAGGLGWSLLTYLQADLKRGIDIVLEAV DFESIVQDADLVITGEGRIDSQTVHGKTPIGVAKAAKSYDVPVIGIAGSISRDSNAVY QHGIDALFSIVPGAVPLEDAFEHAAEYMERTARDIAASIKLAKTMFLI*" gene complement(3977671..3978819) /gene="glxK" /locus_tag="BSU_40040" /old_locus_tag="BSU40040" promotor_-10 complement(3978858..3978877) /Source="Nicolas_upshift_promotors" /id="U3150" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.982017982017982" /psig=1 /xcortree=3162 /SigmaFactorBS="aatttttatttaaatttttaccatattgcatggtATGTATTT ccagatcaatTATGGTACATTGGAGATCAAtaggttaagtgaatcatgttttgaaaga g" /listShort="glxK, yxaB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3978869) /Source="Nicolas_upshifts" /id="U3150" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.982017982017982" /psig=1 /xcortree=3162 /SigmaFactorBS="aatttttatttaaatttttaccatattgcatggtATGTATTT ccagatcaatTATGGTACATTGGAGATCAAtaggttaagtgaatcatgttttgaaaga g" /listShort="glxK, yxaB" /GFF_Attribute="listLong" promotor_-35 complement(3978888..3978895) /Source="Nicolas_upshift_promotors" /id="U3150" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.982017982017982" /psig=1 /xcortree=3162 /SigmaFactorBS="aatttttatttaaatttttaccatattgcatggtATGTATTT ccagatcaatTATGGTACATTGGAGATCAAtaggttaagtgaatcatgttttgaaaga g" /listShort="glxK, yxaB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 3978941..3978948 /Source="Nicolas_upshift_promotors" /id="U3151" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.877122877122877" /psig=1 /xcortree=1787 /SigmaFactorBS="gtaaaaatttaaataaaaattagaaatgaaagTGTTTGCAta aaagaaatattCACGTTATCATACTTGTATAcaagtatactccttgagtgaggaaggt g" /listShort="gntR, gntK, gntP, gntZ" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3978962..3978981 /Source="Nicolas_upshift_promotors" /id="U3151" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.877122877122877" /psig=1 /xcortree=1787 /SigmaFactorBS="gtaaaaatttaaataaaaattagaaatgaaagTGTTTGCAta aaagaaatattCACGTTATCATACTTGTATAcaagtatactccttgagtgaggaaggt g" /listShort="gntR, gntK, gntP, gntZ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3978969 /Source="Nicolas_upshifts" /id="U3151" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.877122877122877" /psig=1 /xcortree=1787 /SigmaFactorBS="gtaaaaatttaaataaaaattagaaatgaaagTGTTTGCAta aaagaaatattCACGTTATCATACTTGTATAcaagtatactccttgagtgaggaaggt g" /listShort="gntR, gntK, gntP, gntZ" /GFF_Attribute="listLong" CDS 3979015..3979746 /gene="gntR" /locus_tag="BSU_40050" /old_locus_tag="BSU40050" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:7476858, 7642511, 8655507, 9106211, 26151451" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7476858, 7642511, 8655507, 9106211, 26151451; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator (GntR-gluconate)" /protein_id="NP_391885.1" /db_xref="EnsemblGenomes-Gn:BSU40050" /db_xref="EnsemblGenomes-Tr:CAB16042" /db_xref="GOA:P10585" /db_xref="InterPro:IPR000524" /db_xref="InterPro:IPR008920" /db_xref="InterPro:IPR011711" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG10648" /db_xref="UniProtKB/Swiss-Prot:P10585" /translation="MLDSKDLLYPAKWLSKASTGVRVAYELRMRIVSGLIESGTILSE NTIAAEFSVSRSPVREALKILASEKIIRLERMGAVVIGLTEKKIAEIYDVRLLLETFV FERLVKIDIEPLVKDLSKILEMMKVSIKYEDADEFSFQDVLFHETIIRAIDHSYIQMI WNNLKPVMESFILLSMRVRLKEKYEDFTRILDNHELYIQAIKTKDRALMIQSLHQNFD DVQDKVEDLWLSQQMLAKGAEYNND*" gene 3979015..3979746 /gene="gntR" /locus_tag="BSU_40050" /old_locus_tag="BSU40050" CDS 3979739..3981280 /gene="gntK" /locus_tag="BSU_40060" /old_locus_tag="BSU40060" /EC_number="2.7.1.12" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:1659648, 2537826, 3020045, 11468405" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1659648, 2537826, 3020045, 11468405; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="D-gluconate kinase" /protein_id="NP_391886.1" /db_xref="EnsemblGenomes-Gn:BSU40060" /db_xref="EnsemblGenomes-Tr:CAB16043" /db_xref="GOA:P12011" /db_xref="InterPro:IPR000577" /db_xref="InterPro:IPR006002" /db_xref="InterPro:IPR018483" /db_xref="InterPro:IPR018484" /db_xref="InterPro:IPR018485" /db_xref="SubtiList:BG10649" /db_xref="UniProtKB/Swiss-Prot:P12011" /translation="MTSYMLGIDIGTTSTKAVLFSENGDVVQKESIGYPLYTPDISTA EQNPEEIFQAVIHTTARITKQHPEKRISFISFSSAMHSVIAIDENDKPLTPCITWADN RSEGWAHKIKEELNGHEVYKRTGTPIHPMAPLSKIAWITNERKEIASKAKKYIGIKEY IFKQLFNEYVIDYSLASATGMMNLKGLDWDEEALRIAGITPDHLSKLVPTTEIFQHCS PEIAIQMGIDPETPFVIGASDGVLSNLGVNAIKKGEIAVTIGTSGAIRTIIDKPQTDE KGRIFCYALTDKHWVIGGPVNNGGIVLRWIRDEFASSEIETATRLGIDPYDVLTKIAQ RVRPGSDGLLFHPYLAGERAPLWNPDVRGSFFGLTMSHKKEHMIRAALEGVIYNLYTV FLALTECMDGPVTRIQATGGFARSEVWRQMMSDIFESEVVVPESYESSCLGACILGLY ATGKIDSFDAVSDMIGSTYRHTPIEDSAKEYRTLMPIFINLSRLLENQYTQIADYQRG LITHK*" gene 3979739..3981280 /gene="gntK" /locus_tag="BSU_40060" /old_locus_tag="BSU40060" CDS 3981309..3982655 /gene="gntP" /locus_tag="BSU_40070" /old_locus_tag="BSU40070" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:3020045, 15849754, 1659648, 16850406" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 3020045, 15849754, 1659648, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="gluconate/proton permease" /protein_id="NP_391887.1" /db_xref="EnsemblGenomes-Gn:BSU40070" /db_xref="EnsemblGenomes-Tr:CAB16044" /db_xref="GOA:P12012" /db_xref="InterPro:IPR003474" /db_xref="SubtiList:BG10650" /db_xref="UniProtKB/Swiss-Prot:P12012" /translation="MPLIIVALGILALLFLIMGLKLNTFISLLVVSFGVALALGMPFD KVVSSIEAGIGGTLGHIALIFGLGAMLGKLIADSGGAQRIAMTLVNKFGEKNIQWAVV IASFIIGIALFFEVGLVLLIPIVFAISRELKISILFLGIPMVAALSVTHGFLPPHPGP TAIAGEYGANIGEVLLYGFIVAVPTVLIAGPLFTKFAKKIVPASFAKNGNIASLGTQK TFNLEETPGFGISVFTAMLPIIIMSVATIIDLLQETIGFADNGVLAFIRLIGNASTAM IISLLVAVYTMGIKRNIPVKTVMDSCSTAISQIGMMLLIIGGGGAFKQVLINGGVGDY VADLFKGTALSPIILAWLIAAILRISLGSATVAALSTTGLVIPLLGHSDVNLALVVLA TGAGSVIASHVNDAGFWMFKEYFGLSMKETFATWTLLETIISVAGLGFILLLSLVV*" gene 3981309..3982655 /gene="gntP" /locus_tag="BSU_40070" /old_locus_tag="BSU40070" promotor_-35 3982108..3982112 /Source="Nicolas_upshift_promotors" /id="U3152" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.801198801198801" /psig="0.998001998001998" /xcortree=2695 /SigmaFactorBS="tttgcagataacggagttttagcttttatcaGATTGattgga aacgcatcgACTGCTATGATTATTTCGTTattggtcgcagtctatacaatgggcatca a" /listShort="gntZ" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3982128..3982147 /Source="Nicolas_upshift_promotors" /id="U3152" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.801198801198801" /psig="0.998001998001998" /xcortree=2695 /SigmaFactorBS="tttgcagataacggagttttagcttttatcaGATTGattgga aacgcatcgACTGCTATGATTATTTCGTTattggtcgcagtctatacaatgggcatca a" /listShort="gntZ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3982137 /Source="Nicolas_upshifts" /id="U3152" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.801198801198801" /psig="0.998001998001998" /xcortree=2695 /SigmaFactorBS="tttgcagataacggagttttagcttttatcaGATTGattgga aacgcatcgACTGCTATGATTATTTCGTTattggtcgcagtctatacaatgggcatca a" /listShort="gntZ" /GFF_Attribute="listLong" CDS 3982678..3984084 /gene="gntZ" /locus_tag="BSU_40080" /old_locus_tag="BSU40080" /EC_number="1.1.1.343" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:15231785, 9535092, 9931298" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15231785, 9535092, 9931298; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="6-phosphogluconate dehydrogenase (NAD+-dependent)" /protein_id="NP_391888.1" /db_xref="EnsemblGenomes-Gn:BSU40080" /db_xref="EnsemblGenomes-Tr:CAB16045" /db_xref="GOA:P12013" /db_xref="InterPro:IPR006113" /db_xref="InterPro:IPR006114" /db_xref="InterPro:IPR006115" /db_xref="InterPro:IPR006183" /db_xref="InterPro:IPR006184" /db_xref="InterPro:IPR008927" /db_xref="InterPro:IPR013328" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG10651" /db_xref="UniProtKB/Swiss-Prot:P12013" /translation="MFNSIGVIGLGVMGSNIALNMANKGENVAVYNYTRDLTDQLIQK LDGQSLSPYYELEDFVQSLEKPRKIFLMVTAGKPVDSVIQSLKPLLEEGDVIMDGGNS HYEDTERRYDELKEKGIGYLGVGISGGEVGALTGPSIMPGGDRDVYEKAAPILTKIAA QVGDDPCCVYIGPKGAGHFTKMVHNGIEYADMQLIAEAYTFLRETLRLPLDEIASIFE TWNQGELKSYLIEITAEILRKKDEKTGQPLIDVILDKTGQKGTGKWTSMQAIDNGIPS TIITESLFARYLSSLKEERMAAQDVLAGPEAEEKHLDKDTWIEYVRQALYMGKVCAYA QGFAQYKMSSELYGWNLPLKDIALIFRGGCIIRADFLNVISEAFSEQPNLANLLIAPY FTDKLHAYQTGLRKVVCEGISTGISFPCLTTALSYYDGYRTGRSNANLLQAQRDYFGA HTYERTDMDGVFHTNWSE*" gene 3982678..3984084 /gene="gntZ" /locus_tag="BSU_40080" /old_locus_tag="BSU40080" downshifts 3984073 /Source="Nicolas_upshifts" /id="D2072" /incds=0 /nref=128 /ntot=228 /MaxReadThrough="3.81668" /MaxDrop="5.52642" /score="20.2280166" /energy="-10.2" /TU="NA" /idTUdmin="U3151" /TUdmin=0 /isTUend="TRUE" misc_feature 3984181..3984200 /Source="Nicolas_upshift_promotors" /id="U3153" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.898101898101898" /psig=1 /xcortree=620 /SigmaFactorBS="tttttttcttctatcccaaacaacagaagacataagttatgt tttaaatatcataaacAGTGATACAATAATAGCTAGaaacaatccccaagatcatcat g" /listShort="S1540" /listLong="ahpC, ahpF" /label="promotor_single_box" /note="Geneious type: promotor_single_box" S_feature 3984183..3984474 /Source="Nicolas_S_feature" /locus_tag="new_4118585_4118876" /HighExp="S8, Etha, Sw, T0.30H, Cold, H2O2, B60, S5, S4, BC" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1540" upshifts 3984183 /Source="Nicolas_upshifts" /id="U3153" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.898101898101898" /psig=1 /xcortree=620 /SigmaFactorBS="tttttttcttctatcccaaacaacagaagacataagttatgt tttaaatatcataaacAGTGATACAATAATAGCTAGaaacaatccccaagatcatcat g" /listShort="S1540" /listLong="ahpC, ahpF" promotor_-35 3984447..3984454 /Source="Nicolas_upshift_promotors" /id="U3154" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.532467532467532" /psig=1 /xcortree=2087 /SigmaFactorBS="cctttattaagatgaaaaaaagtaggttatgGCTTGACAaaa aatatatattaATTAATAATTCATATATAATtagaattattattgaaagcgattatgc t" /listShort="ahpC, ahpF" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3984469..3984488 /Source="Nicolas_upshift_promotors" /id="U3154" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.532467532467532" /psig=1 /xcortree=2087 /SigmaFactorBS="cctttattaagatgaaaaaaagtaggttatgGCTTGACAaaa aatatatattaATTAATAATTCATATATAATtagaattattattgaaagcgattatgc t" /listShort="ahpC, ahpF" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3984476 /Source="Nicolas_upshifts" /id="U3154" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.532467532467532" /psig=1 /xcortree=2087 /SigmaFactorBS="cctttattaagatgaaaaaaagtaggttatgGCTTGACAaaa aatatatattaATTAATAATTCATATATAATtagaattattattgaaagcgattatgc t" /listShort="ahpC, ahpF" /GFF_Attribute="listLong" promotor_-35 3984498..3984505 /Source="Nicolas_upshift_promotors" /id="U3156" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.636363636363636" /psig="0.983016983016983" /xcortree=2089 /SigmaFactorBS="aattcatatataattagaattatTATTGAAAgcgattatgct ttcTAATACATTTTTAGGAGGAAtatacattatgtctttaatcggtaaagaagtactt c" /listShort="ahpC, ahpF" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3984520..3984539 /Source="Nicolas_upshift_promotors" /id="U3156" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.636363636363636" /psig="0.983016983016983" /xcortree=2089 /SigmaFactorBS="aattcatatataattagaattatTATTGAAAgcgattatgct ttcTAATACATTTTTAGGAGGAAtatacattatgtctttaatcggtaaagaagtactt c" /listShort="ahpC, ahpF" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3984523) /Source="Nicolas_upshifts" /id="U3155" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.914085914085914" /psig="0.047952047952048" /xcortree=299 /SigmaFactorBS="ttcgaatggaagtacttctttaccgattaaaGACATaatgta tATTCCTCCTAAAAATgtattagaaagcataatcgctttcaataataattctaattat a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 complement(3984526..3984540) /Source="Nicolas_upshift_promotors" /id="U3155" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.914085914085914" /psig="0.047952047952048" /xcortree=299 /SigmaFactorBS="ttcgaatggaagtacttctttaccgattaaaGACATaatgta tATTCCTCCTAAAAATgtattagaaagcataatcgctttcaataataattctaattat a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3984535 /Source="Nicolas_upshifts" /id="U3156" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.636363636363636" /psig="0.983016983016983" /xcortree=2089 /SigmaFactorBS="aattcatatataattagaattatTATTGAAAgcgattatgct ttcTAATACATTTTTAGGAGGAAtatacattatgtctttaatcggtaaagaagtactt c" /listShort="ahpC, ahpF" /GFF_Attribute="listLong" promotor_-35 complement(3984548..3984552) /Source="Nicolas_upshift_promotors" /id="U3155" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.914085914085914" /psig="0.047952047952048" /xcortree=299 /SigmaFactorBS="ttcgaatggaagtacttctttaccgattaaaGACATaatgta tATTCCTCCTAAAAATgtattagaaagcataatcgctttcaataataattctaattat a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" CDS 3984548..3985111 /gene="ahpC" /locus_tag="BSU_40090" /old_locus_tag="BSU40090" /EC_number="1.11.1.5" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:8932315, 14766928, 26322180" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8932315, 14766928, 26322180; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="alkyl hydroperoxide reductase (small subunit)" /protein_id="NP_391889.1" /db_xref="EnsemblGenomes-Gn:BSU40090" /db_xref="EnsemblGenomes-Tr:CAB16046" /db_xref="GOA:P80239" /db_xref="InterPro:IPR000866" /db_xref="InterPro:IPR013766" /db_xref="InterPro:IPR017559" /db_xref="InterPro:IPR019479" /db_xref="InterPro:IPR024706" /db_xref="InterPro:IPR036249" /db_xref="SubtiList:BG11385" /db_xref="UniProtKB/Swiss-Prot:P80239" /translation="MSLIGKEVLPFEAKAFKNGEFIDVTNEDLKGQWSVFCFYPADFS FVCPTELEDLQEQYAALKELGVEVYSVSTDTHFVHKGWHDSSEKISKITYAMIGDPSQ TISRNFDVLDEETGLADRGTFIIDPDGVIQTVEINAGGIGRDASNLVNKVKAAQYVRQ NPGEVCPAKWEEGGETLTPSLDLVGKI*" gene 3984548..3985111 /gene="ahpC" /locus_tag="BSU_40090" /old_locus_tag="BSU40090" CDS 3985125..3986654 /gene="ahpF" /locus_tag="BSU_40100" /old_locus_tag="BSU40100" /EC_number="1.6.99.3" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:8932314, 14766928, 16232966, 23899494" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8932314, 14766928, 16232966, 23899494; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="alkyl hydroperoxide reductase (large subunit)" /protein_id="NP_391890.1" /db_xref="EnsemblGenomes-Gn:BSU40100" /db_xref="EnsemblGenomes-Tr:CAB16047" /db_xref="GOA:P42974" /db_xref="InterPro:IPR000103" /db_xref="InterPro:IPR002109" /db_xref="InterPro:IPR008255" /db_xref="InterPro:IPR012081" /db_xref="InterPro:IPR012336" /db_xref="InterPro:IPR023753" /db_xref="InterPro:IPR036188" /db_xref="InterPro:IPR036249" /db_xref="SubtiList:BG11204" /db_xref="UniProtKB/Swiss-Prot:P42974" /translation="MVLDANIKAQLNQYMQLIENDIVLKVSAGEDDTSKDMLALVDEL ASMSSKISVEKAELNRTPSFSVNRVGEDTGVTFAGIPLGHEFTSLVLALLQVSGRPPK VDQKVIDQVKKISGEYHFESYISLTCHNCPDVVQALNMMSVLNPNITHTMIDGAAYKA EVESKNIMAVPTVYLNGESFGSGRMTLEEILAKMGSGTDASEFADKEPFDVLVVGGGP AGASAAIYTARKGIRTGVVAERFGGQVLDTMSIENFISVKATEGPKLAASLEEHVKEY DIDVMNLQRAKRLEKKDLFELELENGAVLKSKTVILSTGARWRNVNVPGEQEFKNKGV AYCPHCDGPLFEGKDVAVIGGGNSGIEAAIDLAGIVNHVTVLEFAPELKADEVLQKRL YSLPNVTVVKNAQTKEITGDQSVNGITYVDRETGEEKHVELQGVFVQIGLVPNTEWLE GTVERNRMGEIIVDKHGATSVPGLFAAGDCTDSAYNQIIISMGSGATAALGAFDYLIR N*" gene 3985125..3986654 /gene="ahpF" /locus_tag="BSU_40100" /old_locus_tag="BSU40100" downshifts complement(3986481) /Source="Nicolas_upshifts" /id="D2073" /incds=1 /nref=1 /ntot=9 /MaxReadThrough="3.25325" /MaxDrop="3.69049" /score="1.76901559" /energy="-18" /TU="NA" /idTUdmin="U3157" /TUdmin=198 /isTUend="FALSE" downshifts 3986647 /Source="Nicolas_upshifts" /id="D2074" /incds=0 /nref=248 /ntot=268 /MaxReadThrough="3.92009" /MaxDrop="8.88048" /score="33.1934883" /energy="-19.6" /TU="U3154" /idTUdmin="U3156" /TUdmin=0 /isTUend="TRUE" S_feature complement(3986680..3986763) /Source="Nicolas_S_feature" /locus_tag="new_4121082_4121165_c" /HighExp="G150, C30, LPhT, G135, S8, LBGstat, T0.30H, G180, Diami, Oxctl" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1541" downshifts complement(3986723) /Source="Nicolas_upshifts" /id="D2075" /incds=0 /nref=1 /ntot=40 /MaxReadThrough="3.37922" /MaxDrop="4.44094" /score="1.76901559" /energy="-18" /TU="U3157" /idTUdmin="U3157" /TUdmin="-44" /isTUend="FALSE" CDS complement(3986764..3988203) /gene="bglA" /locus_tag="BSU_40110" /old_locus_tag="BSU40110" /EC_number="3.2.1.86" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:8125345, 14652714, 15139916" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 8125345, 14652714, 15139916; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="aryl-6-phospho-beta-glucosidase" /protein_id="NP_391891.1" /db_xref="EnsemblGenomes-Gn:BSU40110" /db_xref="EnsemblGenomes-Tr:CAB16048" /db_xref="GOA:P42973" /db_xref="InterPro:IPR001360" /db_xref="InterPro:IPR017853" /db_xref="InterPro:IPR018120" /db_xref="InterPro:IPR033132" /db_xref="SubtiList:BG11203" /db_xref="UniProtKB/Swiss-Prot:P42973" /translation="MGNMPKDFLWGGALAAHQFEGGWNQGGKGPSVVDVMTAGAHGVP RKITDTIEENEFYPNHEAIDFYHRYKEDIALFAEMGLKCLRTSIGWSRIFPKGDEAEP NEAGLQFYDDVFDELLKHGIEPVITLSHFEMPLHLAREYGGFRNRKVVDFFVNFAEAC FTRYKDKVKYWMTFNEINNQMDVNNPLFLWTNSGVVVGENENAKEVMYQTAHHELVAS ALAVAKGKDINPEFQIGAMVSHVPIYPFSSNPEDVMLAEEEMRQRYFFPDVQVRGYYP SYALKEFEREGYNITFEDGDDEILRNGTVDYLGFSYYMSTTVKSDVKNDNTGDIVNGG LPNGVENPYITSSDWGWAIDPTGLRYTLNRFYDRYQIPLFIVENGFGAVDTLEEDGKV HDPERIQYLKSHIEALKKAVTYDGVDLIGYTPWGIIDIVSFTTGEMKKRYGMIYVDRD NEGNGSMKRYKKDSFEWYKNVIQTNGEEL*" gene complement(3986764..3988203) /gene="bglA" /locus_tag="BSU_40110" /old_locus_tag="BSU40110" CDS complement(3988217..3988447) /gene="ptsJ" /locus_tag="BSU_40120" /old_locus_tag="BSU40120" /EC_number="2.7.1.-" /function="16.3: Control" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:12867744, 28731580" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12867744, 28731580; Product type t: transporter" /codon_start=1 /transl_table=11 /product="glucose phosphotransferase system enzyme IIA component" /protein_id="NP_391892.1" /db_xref="EnsemblGenomes-Gn:BSU40120" /db_xref="EnsemblGenomes-Tr:CAB16049" /db_xref="GOA:O32292" /db_xref="InterPro:IPR001127" /db_xref="InterPro:IPR011055" /db_xref="SubtiList:BG14172" /db_xref="UniProtKB/Swiss-Prot:O32292" /translation="MVTPTKHAIGLRSASGVELLAHIGLDTVTFDGTPFSLKVKEGDT VKKGEVLVEFDKAFIEDIEESALHQKIFTVVS*" gene complement(3988217..3988447) /gene="ptsJ" /locus_tag="BSU_40120" /old_locus_tag="BSU40120" S_feature complement(3988448..3988659) /Source="Nicolas_S_feature" /locus_tag="new_4122850_4123061_c" /HighExp="G150, LPhT, T0.30H, Diami, G135, LBGstat, G180, Oxctl, Lbexp, dia0" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1542" promotor_-10 complement(3988656..3988675) /Source="Nicolas_upshift_promotors" /id="U3157" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.811188811188811" /psig=1 /xcortree=1576 /SigmaFactorBS="tagtgcgtaaatattttgtttcggAATTGATAaattataccg ttacAATTATAATGAAAGCGTAACcaaaacgaaggggtgggtgaaatgtcggggaaag t" /listShort="S1542, yyzE, bglA, S1541" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3988661) /Source="Nicolas_upshifts" /id="U3157" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.811188811188811" /psig=1 /xcortree=1576 /SigmaFactorBS="tagtgcgtaaatattttgtttcggAATTGATAaattataccg ttacAATTATAATGAAAGCGTAACcaaaacgaaggggtgggtgaaatgtcggggaaag t" /listShort="S1542, yyzE, bglA, S1541" /GFF_Attribute="listLong" promotor_-35 complement(3988690..3988697) /Source="Nicolas_upshift_promotors" /id="U3157" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.811188811188811" /psig=1 /xcortree=1576 /SigmaFactorBS="tagtgcgtaaatattttgtttcggAATTGATAaattataccg ttacAATTATAATGAAAGCGTAACcaaaacgaaggggtgggtgaaatgtcggggaaag t" /listShort="S1542, yyzE, bglA, S1541" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 3988723..3988730 /Source="Nicolas_upshift_promotors" /id="U3158" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.976023976023976" /psig=1 /xcortree=1557 /SigmaFactorBS="ttccgaaacaaaatatttacgcactaaCTATCATTgtaagcg gttTATGCTATAATTTTGACAAGtgaaactaaacgaataaatgaggaatgcgtatgtt a" /listShort="yydK, yyzN" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3988741..3988760 /Source="Nicolas_upshift_promotors" /id="U3158" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.976023976023976" /psig=1 /xcortree=1557 /SigmaFactorBS="ttccgaaacaaaatatttacgcactaaCTATCATTgtaagcg gttTATGCTATAATTTTGACAAGtgaaactaaacgaataaatgaggaatgcgtatgtt a" /listShort="yydK, yyzN" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3988756 /Source="Nicolas_upshifts" /id="U3158" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.976023976023976" /psig=1 /xcortree=1557 /SigmaFactorBS="ttccgaaacaaaatatttacgcactaaCTATCATTgtaagcg gttTATGCTATAATTTTGACAAGtgaaactaaacgaataaatgaggaatgcgtatgtt a" /listShort="yydK, yyzN" /GFF_Attribute="listLong" CDS 3988791..3989501 /gene="yydK" /locus_tag="BSU_40130" /old_locus_tag="BSU40130" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative transcriptional regulator (GntR family)" /protein_id="NP_391893.1" /db_xref="EnsemblGenomes-Gn:BSU40130" /db_xref="EnsemblGenomes-Tr:CAB16050" /db_xref="GOA:Q45591" /db_xref="InterPro:IPR000524" /db_xref="InterPro:IPR011663" /db_xref="InterPro:IPR028978" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="PDB:3BWG" /db_xref="SubtiList:BG11484" /db_xref="UniProtKB/Swiss-Prot:Q45591" /translation="MLKYQQIATEIETYIEEHQLQQGDKLPVLETLMAQFEVSKSTIT KSLELLEQKGAIFQVRGSGIFVRKHKRKGYISLLSNQGFKKDLEDFNVTSKVIELDVR KPTPEAAENLNIGMDEDIYYVKRVRYINGQTLCYEESYYTKSIVTYLNNEIVSHSIFH YIREGLGLKIGFSDLFLHVGQLNEEEAEYLGLEAGLPKLYIESIFHLTNGQPFDYSKI SYNYEQSQFVVQANSFLL*" gene 3988791..3989501 /gene="yydK" /locus_tag="BSU_40130" /old_locus_tag="BSU40130" CDS 3989529..3989687 /gene="yyzN" /locus_tag="BSU_40139" /old_locus_tag="BSU40139" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_003097799.1" /db_xref="EnsemblGenomes-Gn:BSU40139" /db_xref="EnsemblGenomes-Tr:CAX52714" /db_xref="GOA:C0H3T8" /db_xref="UniProtKB/Swiss-Prot:C0H3T8" /translation="MYKIIIPAILAIFALWILLQISLEMSIVKNPMNYFIVFIIFFLF VKMVKEKQ*" gene 3989529..3989687 /gene="yyzN" /locus_tag="BSU_40139" /old_locus_tag="BSU40139" downshifts 3989764 /Source="Nicolas_upshifts" /id="D2076" /incds=0 /nref=16 /ntot=177 /MaxReadThrough="0.96913" /MaxDrop="4.2349" /score="-9.95345673" /energy="-14.7" /TU="NA" /idTUdmin="U3158" /TUdmin="-7" /isTUend="TRUE" CDS complement(3989818..3990540) /gene="liaM" /locus_tag="BSU_40140" /old_locus_tag="BSU40140" /function="16.1: Circulate" /function="16.3: Control" /function="16.4: Excrete" /experiment="publication(s) with functional evidences, PMID:15743949, 15849754, 16850406, 17921301, 28644475" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15743949, 15849754, 16850406, 17921301, 28644475; Product type t : transporter" /codon_start=1 /transl_table=11 /product="permease for export of regulatory peptide LiaD*" /protein_id="NP_391894.1" /db_xref="EnsemblGenomes-Gn:BSU40140" /db_xref="EnsemblGenomes-Tr:CAB16051" /db_xref="GOA:Q45592" /db_xref="SubtiList:BG11483" /db_xref="UniProtKB/Swiss-Prot:Q45592" /translation="MKLEFKKSISNKVIIILGAMFVFLFLLGYFLLVGIDKVSNVTPE MFFFSSYTVATQFGLMLFSFVIAFFINREYSNKNILFYKLIGENIYTFFYKKIAVLFL ECFAFITLGLLIISLMYHDFSHFALLLFLFSAVILQYILIIGTISVLCPNILISIGVS IVYWMTSVILVAISNKTFGFIAPFEAGNTMYPRIERVLQSDNMTLGSNDVLFIILYLV SIIIINAIVLRFSKTRWIKMGL*" gene complement(3989818..3990540) /gene="liaM" /locus_tag="BSU_40140" /old_locus_tag="BSU40140" downshifts complement(3989830) /Source="Nicolas_upshifts" /id="D2077" /incds=0 /nref=225 /ntot=267 /MaxReadThrough="2.70741" /MaxDrop="6.21099" /score="7.49162587" /energy="-10.5" /TU="NA" /idTUdmin="U3160" /TUdmin="-5" /isTUend="TRUE" promotor_-35 3990441..3990444 /Source="Nicolas_upshift_promotors" /id="U3159" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.975024975024975" /psig="0.014985014985015" /xcortree=48 /SigmaFactorBS="tgtaacattactgactttatcgattcCAACaagtaaaaaata accCAGCAaaaataaaaatacaaacattgctcctaaaataatgataactttgttgcta a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3990460..3990464 /Source="Nicolas_upshift_promotors" /id="U3159" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.975024975024975" /psig="0.014985014985015" /xcortree=48 /SigmaFactorBS="tgtaacattactgactttatcgattcCAACaagtaaaaaata accCAGCAaaaataaaaatacaaacattgctcctaaaataatgataactttgttgcta a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3990475 /Source="Nicolas_upshifts" /id="U3159" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.975024975024975" /psig="0.014985014985015" /xcortree=48 /SigmaFactorBS="tgtaacattactgactttatcgattcCAACaagtaaaaaata accCAGCAaaaataaaaatacaaacattgctcctaaaataatgataactttgttgcta a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" CDS complement(3990561..3991190) /gene="liaL" /locus_tag="BSU_40150" /old_locus_tag="BSU40150" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:15743949, 15849754, 16850406, 17921301, 28644475" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15743949, 15849754, 16850406, 17921301, 28644475; Product type t : transporter" /codon_start=1 /transl_table=11 /product="ABC transporter for regulatory peptide LiaD* (ATP-binding protein)" /protein_id="NP_391895.1" /db_xref="EnsemblGenomes-Gn:BSU40150" /db_xref="EnsemblGenomes-Tr:CAB16052" /db_xref="GOA:Q45593" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG11482" /db_xref="UniProtKB/Swiss-Prot:Q45593" /translation="MNIANYTLKVKGKTLLQDTDLHFSSGKINHVVGKNGVGKSQLAK DFLLNNSKRIGRDIRQNVSLISSSSNIPNDVSKDFLLHFLSKKFDAKMIDKIAYLLNL DNIDGKVLIKNLSDGQKQKLKLLSFLLEDKNIIVLDEITNSLDKKTVIEIHGFLNKYI QENPEKIIINITHDLSDLKAIEGDYYIFNHQEIQQYHSVDKLIEVYINE*" gene complement(3990561..3991190) /gene="liaL" /locus_tag="BSU_40150" /old_locus_tag="BSU40150" S_feature complement(3991191..3991339) /Source="Nicolas_S_feature" /locus_tag="new_4125593_4125741_c" /HighExp="T-0.40H, LoTm, T-2.40H, T0.0H, M9-tran, SMMPr, T-1.40H, GM 150, T-3.40H, T-4.40H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="1, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S1543" CDS complement(3991340..3992098) /gene="liaK" /locus_tag="BSU_40160" /old_locus_tag="BSU40160" /function="16.3: Control" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:15743949, 15849754, 16850406, 17921301, 28644475" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15743949, 15849754, 16850406, 17921301, 28644475; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="membrane metalloprotease acting on modified factor LiaD" /protein_id="NP_391896.2" /db_xref="EnsemblGenomes-Gn:BSU40160" /db_xref="EnsemblGenomes-Tr:CAB16053" /db_xref="GOA:Q45594" /db_xref="SubtiList:BG11481" /db_xref="UniProtKB/Swiss-Prot:Q45594" /translation="MKILKYEDEKYEVLVQNNVFIKDKKSGEYYKNSLNSLSDKQLLR FKMYKEKVSPKFFYLFLSFTALMFILNYIHLIKLQNGLSSVFYGWKMWIIIVIYFIMN IVLHELGHIYSLKFFGKNFDKVGFKLNFYVFPAFYVQLNETYMLSRNEKIIVHLFGLF INYLLINTLELINQFTFSSEALTMAFMLFSSTLLWNLIPILNSDGYKILLAFLSLDEY SRFKTNHWLVLTIQIIGIGLAVNSVVHWILYIVN*" gene complement(3991340..3992098) /gene="liaK" /locus_tag="BSU_40160" /old_locus_tag="BSU40160" promotor_-10 complement(3991788..3991807) /Source="Nicolas_upshift_promotors" /id="U3160" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.353646353646354" /psig=1 /xcortree=2954 /SigmaFactorBS="caaaatggattgtcctcagtattttacggctggaaaaTGTGG ATAattatagttattTATTTTATAATGAATATAGTgcttcatgaactgggacatattt a" /listShort="S1543, yydI, yydJ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3991804) /Source="Nicolas_upshifts" /id="U3160" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.353646353646354" /psig=1 /xcortree=2954 /SigmaFactorBS="caaaatggattgtcctcagtattttacggctggaaaaTGTGG ATAattatagttattTATTTTATAATGAATATAGTgcttcatgaactgggacatattt a" /listShort="S1543, yydI, yydJ" /GFF_Attribute="listLong" promotor_-35 complement(3991820..3991827) /Source="Nicolas_upshift_promotors" /id="U3160" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.353646353646354" /psig=1 /xcortree=2954 /SigmaFactorBS="caaaatggattgtcctcagtattttacggctggaaaaTGTGG ATAattatagttattTATTTTATAATGAATATAGTgcttcatgaactgggacatattt a" /listShort="S1543, yydI, yydJ" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(3992079..3993038) /gene="liaE" /locus_tag="BSU_40170" /old_locus_tag="BSU40170" /EC_number="5.1.1.-" /experiment="publication(s) with functional evidences, PMID:17921301, 18307109, 28644475" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 17921301, 18307109, 28644475; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="AdoMet radical amino acid epimerase modifying factor LiaD" /protein_id="NP_391897.1" /db_xref="EnsemblGenomes-Gn:BSU40170" /db_xref="EnsemblGenomes-Tr:CAB16054" /db_xref="GOA:Q45595" /db_xref="InterPro:IPR007197" /db_xref="InterPro:IPR023404" /db_xref="InterPro:IPR023904" /db_xref="InterPro:IPR034395" /db_xref="SubtiList:BG11480" /db_xref="UniProtKB/Swiss-Prot:Q45595" /translation="MYNKTVSINLDSRCNASCDHCCFSSSPTSTTRMEKEYIRELVTE FAKNKTIQVISFTGGEVFLDYKFLKELMEIIKPYEKQITLISNGFWGLSKKKVQEYFH DMNSLNVIALTISYDEYHAPFVKSSSIKNILEHSRKYPDIDISLNMAVTKDKMSNHIL EELGDSILGVKITKFPMISVGAAKTRIKQENIHKFYSLEDEDSLHCPGYDIVYHHDGE IYPCCSPAIFETKITLREEYNQSFERTVEKLNSNLLLFILRKEGFKWFLNILKENNKI EEFDIPYEFSSICGVCGSLFNSAEKINYFYPYMEKYYNENFKV*" gene complement(3992079..3993038) /gene="liaE" /locus_tag="BSU_40170" /old_locus_tag="BSU40170" downshifts 3993027 /Source="Nicolas_upshifts" /id="D2078" /incds=0 /nref=1 /ntot=14 /MaxReadThrough="3.40583" /MaxDrop="2.5017" /score="-9.12840375" /energy="-9.4" /TU="NA" /idTUdmin="U3161" /TUdmin="-220" /isTUend="FALSE" misc_feature 3993074..3993077 /Source="Nicolas_upshift_promotors" /id="U3161" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.380619380619381" /psig="0.304695304695305" /xcortree=119 /SigmaFactorBS="actgttttattatacatgaaatatcccccaacaaatggtaaa ggagagttagACTCtcctttgtacccctctaattaatgaccacttccaagaatccagc g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 3993082 /Source="Nicolas_upshifts" /id="U3161" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.380619380619381" /psig="0.304695304695305" /xcortree=119 /SigmaFactorBS="actgttttattatacatgaaatatcccccaacaaatggtaaa ggagagttagACTCtcctttgtacccctctaattaatgaccacttccaagaatccagc g" /GFF_Attribute="listShort" /GFF_Attribute="listLong" CDS complement(3993096..3993245) /gene="liaD" /locus_tag="BSU_40180" /old_locus_tag="BSU40180" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:15101989, 17921301, 28644475" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15101989, 17921301, 28644475; Product type r: regulator" /codon_start=1 /transl_table=11 /product="precursor of exported modified peptide (epipeptide) controlling LiaRS activity" /protein_id="NP_391898.1" /db_xref="EnsemblGenomes-Gn:BSU40180" /db_xref="EnsemblGenomes-Tr:CAB16055" /db_xref="InterPro:IPR023898" /db_xref="SubtiList:BG11479" /db_xref="UniProtKB/Swiss-Prot:Q45596" /translation="MKKEITNNETVKNLEFKGLLDESQKLAKVNDLWYFVKSKENRWI LGSGH*" gene complement(3993096..3993245) /gene="liaD" /locus_tag="BSU_40180" /old_locus_tag="BSU40180" downshifts complement(3993103) /Source="Nicolas_upshifts" /id="D2079" /incds=0 /nref=99 /ntot=172 /MaxReadThrough="7.62324" /MaxDrop="6.01674" /score="7.49162587" /energy="-10.5" /TU="U3163" /idTUdmin="U3167" /TUdmin=2794 /isTUend="FALSE" misc_feature 3993154..3993171 /Source="Nicolas_upshift_promotors" /id="U3162" /multdbtbs="-" /comp="M3" /sig="Sig-" /pcomp="0.342657342657343" /psig="0.342657342657343" /xcortree=651 /SigmaFactorBS="atgaccacttccaagaatccagcgattttcttttgattttac aaaataccaaagaTCATTCACTTTTGCTAACttttgtgattcatctaatagaccctta a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 3993159 /Source="Nicolas_upshifts" /id="U3162" /multdbtbs="-" /comp="M3" /sig="Sig-" /pcomp="0.342657342657343" /psig="0.342657342657343" /xcortree=651 /SigmaFactorBS="atgaccacttccaagaatccagcgattttcttttgattttac aaaataccaaagaTCATTCACTTTTGCTAACttttgtgattcatctaatagaccctta a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" downshifts 3993240 /Source="Nicolas_upshifts" /id="D2080" /incds=0 /nref=99 /ntot=170 /MaxReadThrough="2.55247" /MaxDrop="5.95806" /score="-9.12840375" /energy="-9.4" /TU="NA" /idTUdmin="U3161" /TUdmin="-7" /isTUend="TRUE" promotor_-10 complement(3993266..3993285) /Source="Nicolas_upshift_promotors" /id="U3163" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.998001998001998" /psig=1 /xcortree=2870 /SigmaFactorBS="ccaagaatagtgacatttttcagattttttaggtacaataTA TTGACAtgtattgaatgataTAGAATAATTGGTTTATATTagaaaaggaggagggata a" /listShort="yydF, yydG, yydH, S1543, yydI, yydJ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(3993287) /Source="Nicolas_upshifts" /id="U3163" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.998001998001998" /psig=1 /xcortree=2870 /SigmaFactorBS="ccaagaatagtgacatttttcagattttttaggtacaataTA TTGACAtgtattgaatgataTAGAATAATTGGTTTATATTagaaaaggaggagggata a" /listShort="yydF, yydG, yydH, S1543, yydI, yydJ" /GFF_Attribute="listLong" promotor_-35 complement(3993300..3993307) /Source="Nicolas_upshift_promotors" /id="U3163" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.998001998001998" /psig=1 /xcortree=2870 /SigmaFactorBS="ccaagaatagtgacatttttcagattttttaggtacaataTA TTGACAtgtattgaatgataTAGAATAATTGGTTTATATTagaaaaggaggagggata a" /listShort="yydF, yydG, yydH, S1543, yydI, yydJ" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 3993580..3993587 /Source="Nicolas_upshift_promotors" /id="U3164" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.924075924075924" /psig=1 /xcortree=1990 /SigmaFactorBS="tgcttaccccatttggcacctctttctctcgtttTAATTGTC tctaaaagcagttaTGCGGTACTATCATATAAAGgtccaatgtttaaaaataatgtca t" /listShort="fbp, S1544" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3993602..3993621 /Source="Nicolas_upshift_promotors" /id="U3164" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.924075924075924" /psig=1 /xcortree=1990 /SigmaFactorBS="tgcttaccccatttggcacctctttctctcgtttTAATTGTC tctaaaagcagttaTGCGGTACTATCATATAAAGgtccaatgtttaaaaataatgtca t" /listShort="fbp, S1544" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 3993606 /Source="Nicolas_upshifts" /id="U3164" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.924075924075924" /psig=1 /xcortree=1990 /SigmaFactorBS="tgcttaccccatttggcacctctttctctcgtttTAATTGTC tctaaaagcagttaTGCGGTACTATCATATAAAGgtccaatgtttaaaaataatgtca t" /listShort="fbp, S1544" /GFF_Attribute="listLong" CDS 3993717..3995642 /gene="fbp" /locus_tag="BSU_40190" /old_locus_tag="BSU40190" /EC_number="3.1.3.11" /function="16.3: Control" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:221467, 9696785, 19270101" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 221467, 9696785, 19270101; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="fructose-1,6-bisphosphatase" /protein_id="NP_391899.2" /db_xref="EnsemblGenomes-Gn:BSU40190" /db_xref="EnsemblGenomes-Tr:CAB16056" /db_xref="GOA:Q45597" /db_xref="InterPro:IPR009164" /db_xref="InterPro:IPR029052" /db_xref="SubtiList:BG11478" /db_xref="UniProtKB/Swiss-Prot:Q45597" /translation="MESKYLDLLAQKYDCEEKVVTEIINLKAILNLPKGTEHFVSDLH GEYQAFQHVLRNGSGRVKEKIRDIFSGVIYDREIDELAALVYYPEDKLKLIKHDFDAK EALNEWYKETIHRMIKLVSYCSSKYTRSKLRKALPAQFAYITEELLYKTEQAGNKEQY YSEIIDQIIELGQADKLITGLAYSVQRLVVDHLHVVGDIYDRGPQPDRIMEELINYHS VDIQWGNHDVLWIGAYSGSKVCLANIIRICARYDNLDIIEDVYGINLRPLLNLAEKYY DDNPAFRPKADENRPEDEIKQITKIHQAIAMIQFKLESPIIKRRPNFNMEERLLLEKI DYDKNEITLNGKTYQLENTCFATINPEQPDQLLEEEAEVIDKLLFSVQHSEKLGRHMN FMMKKGSLYLKYNGNLLIHGCIPVDENGNMETMMIEDKPYAGRELLDVFERFLREAFA HPEETDDLATDMAWYLWTGEYSSLFGKRAMTTFERYFIKEKETHKEKKNPYYYLREDE ATCRNILAEFGLNPDHGHIINGHTPVKEIEGEDPIKANGKMIVIDGGFSKAYQSTTGI AGYTLLYNSYGMQLVAHKHFNSKAEVLSTGTDVLTVKRLVDKELERKKVKETNVGEEL LQEVAILESLREYRYMK*" gene 3993717..3995642 /gene="fbp" /locus_tag="BSU_40190" /old_locus_tag="BSU40190" S_feature 3995643..3997007 /Source="Nicolas_S_feature" /locus_tag="new_4130045_4131409" /HighExp="Lbstat, dia5, C30, Gly, Etha, dia15, C90, Fru, G135, Mal" /AntisenseName="yydD" /AntisenseCor="0.44422072328838003" /AntisenseRegPval="-13.7" /CDS_PredictionProba="0.22050400000000001" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1544" S_feature complement(3995855..3996175) /Source="Nicolas_S_feature" /locus_tag="new_4130257_4130577_c" /HighExp="Cold, C30, M/G, S8, Fru, nit, Glu, BMM, Heat, MG 150" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.988" /TUlongSig="NA" /TUlongPSig="NA" /label="S1545" CDS complement(3996176..3997936) /gene="yydD" /locus_tag="BSU_40200" /old_locus_tag="BSU40200" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type f: factor" /codon_start=1 /transl_table=11 /product="putative DNA wielding protein" /protein_id="NP_391900.1" /db_xref="EnsemblGenomes-Gn:BSU40200" /db_xref="EnsemblGenomes-Tr:CAB16057" /db_xref="InterPro:IPR018760" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG11477" /db_xref="UniProtKB/Swiss-Prot:Q45598" /translation="MIVMIIKNLFVCNSQEILKEYKFNAVGVNIILGEKREDHEETNG VGKSTMIECISFLLGKTISNFYTTNEILLNKNVFIVLNVEIDGNQVFLARSFNSPKHG YTLHDTSLTFNLEEWKKVSISVYKKFIEKEILKGEKEDITFAALREYIIRDEKTGFND IVLPNRGGLKQYKLLNYLFTLPTHTEKNIKVFRDKIEKLNSEIKLIESMNINIGDLKV KEDELINEIEDYNRVIYQTKTANKYNNDTNRYSEIKSELNKIQNEIFENEHICKQYQR NIDDLNKKVTKIKELENIEKFYEDIVGFFPEEVKQNYNKVQEFYNFMVESRGSYFKDK IVKIQADLKKLNIKKQGLTEQLESSARILKSNNFIEDISIVMEEQRRKEIELAEVRLR ISDYDKKNHIFDKINELQHEILRVNSMYYDEFQSYSAIVSELKKLFNNLMDVTYNQHG FLDFEYDNRISNAKQSTTGRIKISCSIPDERSHGRLHMKINIFDLTWFLYRCINKCSL NILIHDGSYSNPDPHVKGTLLKHINSSLLENRIGQYFVTINKNELLLDDLQELESKGM IVAKLDRNNEDKNRFFGFRF*" gene complement(3996176..3997936) /gene="yydD" /locus_tag="BSU_40200" /old_locus_tag="BSU40200" downshifts complement(3996219) /Source="Nicolas_upshifts" /id="D2081" /incds=0 /nref=11 /ntot=199 /MaxReadThrough="4.99391" /MaxDrop="4.47843" /score="7.49162587" /energy="-10.5" /TU="U3167" /idTUdmin="U3167" /TUdmin="-322" /isTUend="FALSE" misc_feature 3997004..3997005 /Source="Nicolas_upshift_promotors" /id="U3165" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.67032967032967" /psig="0.255744255744256" /xcortree=83 /SigmaFactorBS="aactccctctactttctaccatgaaattatagaactcttgga ctttattataattCTgttttacttcctctggaaaaaaacctacaatatcttcatagaa t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 3997009 /Source="Nicolas_upshifts" /id="U3165" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.67032967032967" /psig="0.255744255744256" /xcortree=83 /SigmaFactorBS="aactccctctactttctaccatgaaattatagaactcttgga ctttattataattCTgttttacttcctctggaaaaaaacctacaatatcttcatagaa t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" CDS complement(3997936..3998334) /gene="yydC" /locus_tag="BSU_40210" /old_locus_tag="BSU40210" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_391901.1" /db_xref="EnsemblGenomes-Gn:BSU40210" /db_xref="EnsemblGenomes-Tr:CAB16058" /db_xref="SubtiList:BG11476" /db_xref="UniProtKB/Swiss-Prot:Q45599" /translation="MIDLKIETAENILKYSYVLLENEFKNIQIGNDLIPLVNNSPLKK EKAERPEMNHFLLTKYNAVEENILYSSKILYELLEKEKHIDQLFLDYAKSQGIIINLN IERILYLSLTFLYSLGKVSFNQNMISRTES*" gene complement(3997936..3998334) /gene="yydC" /locus_tag="BSU_40210" /old_locus_tag="BSU40210" CDS complement(3998327..3999772) /gene="yydB" /locus_tag="BSU_40220" /old_locus_tag="BSU40220" /function="16.11: Scavenge (Catabolism)" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative phosphohydrolase" /protein_id="NP_391902.1" /db_xref="EnsemblGenomes-Gn:BSU40220" /db_xref="EnsemblGenomes-Tr:CAB16059" /db_xref="GOA:Q45600" /db_xref="InterPro:IPR004843" /db_xref="InterPro:IPR029052" /db_xref="SubtiList:BG11475" /db_xref="UniProtKB/Swiss-Prot:Q45600" /translation="MKVRFLQISDLHFQFQNYDTIVMRDKLLDFIEVLRRESDFDFLL LTGDIAHKGDVYNEDVKEYLNGIIKSMGLSKNNVHLVPGNHDISRDMTRTLLIDSIMK SPNPSEMLDKLDQKATNILVEGQRKFFDFYEDFMGVKYPEEDLHFLYQSEKYNVLSIN TCLLSDKKGEEGTLLTAQMKLYKAIRKMNKEKNKGKVLNIAIGHHTLGCIESSERESI KAHFDDYFIDLYLAGHVHDSSFNITANTNENPFLELVSGAIIKDEYATPEFISVDVNL DNGETEVTYYIWNTEYKYWSKNNQGGRRLQEGKLNYKINRLESLIEKEIEDNDDKIDE DEFKSFIIDFHEYRESYKTFTSNFDNQIGLDKKFYDMKSGETFKRKFDSYSEYFGVIN HIMDSTSYVSADKKELIAETIVDKYLEFHNQYNNGDEIFVKIVNEIYLECHSVLPYSK ALTKKYIKILTCWCIYECEIFNDNKRSVKND*" gene complement(3998327..3999772) /gene="yydB" /locus_tag="BSU_40220" /old_locus_tag="BSU40220" promotor_-35 3999022..3999029 /Source="Nicolas_upshift_promotors" /id="U3166" /multdbtbs="-" /comp="M11" /sig="Sig-" /pcomp="0.353646353646354" /psig="0.430569430569431" /xcortree=94 /SigmaFactorBS="tttataatggctccacttactaattctaagaATGGATTTtca tttgtattTGCAGTAATATTAAATGAAGaatcatgtacatgtcctgccaaatatagat c" /listShort="S1546" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 3999041..3999060 /Source="Nicolas_upshift_promotors" /id="U3166" /multdbtbs="-" /comp="M11" /sig="Sig-" /pcomp="0.353646353646354" /psig="0.430569430569431" /xcortree=94 /SigmaFactorBS="tttataatggctccacttactaattctaagaATGGATTTtca tttgtattTGCAGTAATATTAAATGAAGaatcatgtacatgtcctgccaaatatagat c" /listShort="S1546" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 3999051..4000100 /Source="Nicolas_S_feature" /locus_tag="new_4133453_4134502" /HighExp="C30, Salt, Gly, S8, Etha, LPhT, T0.30H, Heat, C90, M9-stat" /AntisenseName="yydB" /AntisenseCor="0.36202116146901597" /AntisenseRegPval="-9" /CDS_PredictionProba="NA" /TUshortSig="Sig-" /TUshortPSig="0.431" /TUlongSig="NA" /TUlongPSig="NA" /label="S1546" upshifts 3999051 /Source="Nicolas_upshifts" /id="U3166" /multdbtbs="-" /comp="M11" /sig="Sig-" /pcomp="0.353646353646354" /psig="0.430569430569431" /xcortree=94 /SigmaFactorBS="tttataatggctccacttactaattctaagaATGGATTTtca tttgtattTGCAGTAATATTAAATGAAGaatcatgtacatgtcctgccaaatatagat c" /listShort="S1546" /GFF_Attribute="listLong" S_feature complement(3999773..4000033) /Source="Nicolas_S_feature" /locus_tag="new_4134175_4134435_c" /HighExp="Cold, M0t90, Lbtran, M40t90, Lbstat, T0.30H, MG 150, M40t45, Gly, M0t45" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.988" /TUlongSig="NA" /TUlongPSig="NA" /label="S1547" CDS complement(4000034..4000513) /gene="rlmH" /locus_tag="BSU_40230" /old_locus_tag="BSU40230" /EC_number="2.1.1.177" /function="16.6: Maintain" /function="16.8: Protect" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 18755835, 20817755, 22411911, 22720735, 28428565; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="23S rRNA (pseudouridine1915-N3)-methyltransferase" /protein_id="NP_391903.1" /db_xref="EnsemblGenomes-Gn:BSU40230" /db_xref="EnsemblGenomes-Tr:CAB16060" /db_xref="GOA:Q45601" /db_xref="InterPro:IPR003742" /db_xref="InterPro:IPR029026" /db_xref="InterPro:IPR029028" /db_xref="PDB:1TO0" /db_xref="SubtiList:BG11474" /db_xref="UniProtKB/Swiss-Prot:Q45601" /translation="MNINIVTIGKLKEKYLKQGIEEYTKRLSAYAKIDIIELPDEKAP ENLSDQDMKIIKDKEGDRILSKISPDAHVIALAIEGKMKTSEELADTIDKLATYGKSK VTFVIGGSLGLSDTVMKRADEKLSFSKMTFPHQLMRLILVEQIYRAFRINRGEPYHK* " gene complement(4000034..4000513) /gene="rlmH" /locus_tag="BSU_40230" /old_locus_tag="BSU40230" S_feature complement(4000514..4000593) /Source="Nicolas_S_feature" /locus_tag="new_4134916_4134995_c" /HighExp="dia5, LBGtran, T0.30H, Diami, Cold, M0t90, dia0, M0t45, M40t45, Lbtran" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.988" /TUlongSig="NA" /TUlongPSig="NA" /label="S1548" CDS complement(4000594..4000764) /gene="yyzF" /locus_tag="BSU_40239" /old_locus_tag="BSU40239" /function="18: Unknown function" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="YP_003097800.1" /db_xref="EnsemblGenomes-Gn:BSU40239" /db_xref="EnsemblGenomes-Tr:CAX52715" /db_xref="InterPro:IPR025626" /db_xref="UniProtKB/Swiss-Prot:C0H3T9" /translation="MKQAYYSCEEHIETVLDMYIDDHELPPEIRKIEHTNSLSTACEL CGDPAVYIVGNE*" gene complement(4000594..4000764) /gene="yyzF" /locus_tag="BSU_40239" /old_locus_tag="BSU40239" promotor_-10 complement(4000805..4000824) /Source="Nicolas_upshift_promotors" /id="U3167" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.343656343656344" /psig="0.988011988011988" /xcortree=2306 /SigmaFactorBS="ttgtttgtcgaattgtggataaaactcagcccgaagcaCTAC TAacatgtgaataaaTAGGTTATATTGAGAAGAGAacatttgtaaaaatggaagaaaa c" /listShort="yyzF, S1548, yydA, S1547, yydB, yydC, yydD, S1545" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(4000821) /Source="Nicolas_upshifts" /id="U3167" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.343656343656344" /psig="0.988011988011988" /xcortree=2306 /SigmaFactorBS="ttgtttgtcgaattgtggataaaactcagcccgaagcaCTAC TAacatgtgaataaaTAGGTTATATTGAGAAGAGAacatttgtaaaaatggaagaaaa c" /listShort="yyzF, S1548, yydA, S1547, yydB, yydC, yydD, S1545" /GFF_Attribute="listLong" promotor_-35 complement(4000838..4000843) /Source="Nicolas_upshift_promotors" /id="U3167" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.343656343656344" /psig="0.988011988011988" /xcortree=2306 /SigmaFactorBS="ttgtttgtcgaattgtggataaaactcagcccgaagcaCTAC TAacatgtgaataaaTAGGTTATATTGAGAAGAGAacatttgtaaaaatggaagaaaa c" /listShort="yyzF, S1548, yydA, S1547, yydB, yydC, yydD, S1545" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 4000887..4000894 /Source="Nicolas_upshift_promotors" /id="U3168" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.549450549450549" /psig="0.994005994005994" /xcortree=415 /SigmaFactorBS="ccacaattcgacaaacaagctgtTGATGACTctatttcgctc gTGTGTTAGTTTGGATGTAACcgatgtgtggggaggtctgcatttgcgctttagatgg g" /listShort="yycS" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 4000907..4000926 /Source="Nicolas_upshift_promotors" /id="U3168" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.549450549450549" /psig="0.994005994005994" /xcortree=415 /SigmaFactorBS="ccacaattcgacaaacaagctgtTGATGACTctatttcgctc gTGTGTTAGTTTGGATGTAACcgatgtgtggggaggtctgcatttgcgctttagatgg g" /listShort="yycS" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 4000924 /Source="Nicolas_upshifts" /id="U3168" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.549450549450549" /psig="0.994005994005994" /xcortree=415 /SigmaFactorBS="ccacaattcgacaaacaagctgtTGATGACTctatttcgctc gTGTGTTAGTTTGGATGTAACcgatgtgtggggaggtctgcatttgcgctttagatgg g" /listShort="yycS" /GFF_Attribute="listLong" CDS 4000949..4001362 /gene="yycS" /locus_tag="BSU_40240" /old_locus_tag="BSU40240" /function="16.5: Explore" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 21911367; Product type s: structure" /codon_start=1 /transl_table=11 /product="putative lipoprotein" /protein_id="NP_391904.1" /db_xref="EnsemblGenomes-Gn:BSU40240" /db_xref="EnsemblGenomes-Tr:CAB16061" /db_xref="SubtiList:BG11472" /db_xref="UniProtKB/Swiss-Prot:Q45603" /translation="MRFRWVWLFVIMLLLAECQPSYWVLEKDRIGEGSPDLEIYANYL QMHDDVKGYQVFTISEGKKMVVVSLGSSEKDKKLEVSDVKFSSKETIVTVERKPAPTA NEKNPFILIGLDKIEGDLIVQDETGDRFEETDYQQ*" gene 4000949..4001362 /gene="yycS" /locus_tag="BSU_40240" /old_locus_tag="BSU40240" downshifts 4001342 /Source="Nicolas_upshifts" /id="D2082" /incds=0 /nref=17 /ntot=131 /MaxReadThrough="1.50241" /MaxDrop="5.73792" /score="16.0382598" /energy="-10.8" /TU="NA" /idTUdmin="U3168" /TUdmin=0 /isTUend="TRUE" CDS complement(4001396..4002622) /gene="yycR" /locus_tag="BSU_40250" /old_locus_tag="BSU40250" /EC_number="1.-.-.-" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 18820069; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative dehydrogenase" /protein_id="NP_391905.1" /db_xref="EnsemblGenomes-Gn:BSU40250" /db_xref="EnsemblGenomes-Tr:CAB16062" /db_xref="GOA:Q45604" /db_xref="InterPro:IPR002328" /db_xref="InterPro:IPR011032" /db_xref="InterPro:IPR013149" /db_xref="InterPro:IPR013154" /db_xref="InterPro:IPR014184" /db_xref="InterPro:IPR036291" /db_xref="SubtiList:BG11471" /db_xref="UniProtKB/Swiss-Prot:Q45604" /translation="MGGMALTGNKAVVYKGKGTVAVEDIGYPELILRDGPGVPKANVN RKCEHGVILKVITTNICGSDQHMVRGRTTAPEGLVLGHEITGEVIETGRDVEFIKKGD IVSVPFNIACGRCVMCKTQKTHVCLNVNPDRPGSAYGYVDMGGWVGGQSEYVMVPYAD FQLLVFPDKEQALEKILDLTMLSDIFPTGFHGAYTAGVQTGSTVYIAGAGPVGLAAAH SAQLLGASTVIVGDLNEDRLAQARSFGCETVNVQKHDRLGEQIEQILGEPTVDAAVDC VGFEASGHGNQGEAPAAVLNSIMDVTQVGGSLGIPGLYVTEDPGAKDADAKTGSLKIR FGLGWAKAHTFVTGQTPAMTYNRNLMKAILSGRAQIAKAVNATVISLDDAPKGYSDFD KGAAKKFVIDPHGTLK*" gene complement(4001396..4002622) /gene="yycR" /locus_tag="BSU_40250" /old_locus_tag="BSU40250" downshifts complement(4001411) /Source="Nicolas_upshifts" /id="D2083" /incds=0 /nref=9 /ntot=123 /MaxReadThrough="0.14321" /MaxDrop="4.77892" /score="8.82768619" /energy="-6.2" /TU="NA" /idTUdmin="U3169" /TUdmin=7 /isTUend="TRUE" promotor_-10 complement(4002645..4002663) /Source="Nicolas_upshift_promotors" /id="U3169" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=518 /SigmaFactorBS="taagaatacagaaaaaacagtcgtgaaAAAGGGAAAgagtca tgccgAACCGAAGTCATGTTCAAGgacggagagtccaaacacatgaatgggaggaatg g" /listShort="yycR" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(4002650) /Source="Nicolas_upshifts" /id="U3169" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=518 /SigmaFactorBS="taagaatacagaaaaaacagtcgtgaaAAAGGGAAAgagtca tgccgAACCGAAGTCATGTTCAAGgacggagagtccaaacacatgaatgggaggaatg g" /listShort="yycR" /GFF_Attribute="listLong" promotor_-35 complement(4002675..4002683) /Source="Nicolas_upshift_promotors" /id="U3169" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=518 /SigmaFactorBS="taagaatacagaaaaaacagtcgtgaaAAAGGGAAAgagtca tgccgAACCGAAGTCATGTTCAAGgacggagagtccaaacacatgaatgggaggaatg g" /listShort="yycR" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(4002685..4002855) /gene="yyzG" /locus_tag="BSU_40259" /old_locus_tag="BSU40259" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_003097801.1" /db_xref="EnsemblGenomes-Gn:BSU40259" /db_xref="EnsemblGenomes-Tr:CAX52716" /db_xref="GOA:C0H3U0" /db_xref="UniProtKB/Swiss-Prot:C0H3U0" /translation="MQTNRVILLAVMICLVSAITVFLLNGCKVDFLDIGGTIIGCFLG IFVVVRIQKKQS*" gene complement(4002685..4002855) /gene="yyzG" /locus_tag="BSU_40259" /old_locus_tag="BSU40259" promotor_-10 complement(4002874..4002892) /Source="Nicolas_upshift_promotors" /id="U3170" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.681318681318681" /psig="0.681318681318681" /xcortree=259 /SigmaFactorBS="ttatgaagagactggtgtgaagtctctttttttgttgaacCG AAGTTtgcagaggattttGGGTATGGTTTAGAAACGAatccaaaggaggaattacatg c" /listShort="yyzG, yycR" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(4002892) /Source="Nicolas_upshifts" /id="U3170" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.681318681318681" /psig="0.681318681318681" /xcortree=259 /SigmaFactorBS="ttatgaagagactggtgtgaagtctctttttttgttgaacCG AAGTTtgcagaggattttGGGTATGGTTTAGAAACGAatccaaaggaggaattacatg c" /listShort="yyzG, yycR" /GFF_Attribute="listLong" promotor_-35 complement(4002906..4002912) /Source="Nicolas_upshift_promotors" /id="U3170" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp="0.681318681318681" /psig="0.681318681318681" /xcortree=259 /SigmaFactorBS="ttatgaagagactggtgtgaagtctctttttttgttgaacCG AAGTTtgcagaggattttGGGTATGGTTTAGAAACGAatccaaaggaggaattacatg c" /listShort="yyzG, yycR" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(4002960..4003208) /gene="yycQ" /locus_tag="BSU_40260" /old_locus_tag="BSU40260" /function="18: Unknown function" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="conserved membrane protein" /protein_id="NP_391906.1" /db_xref="EnsemblGenomes-Gn:BSU40260" /db_xref="EnsemblGenomes-Tr:CAB16063" /db_xref="GOA:Q45605" /db_xref="InterPro:IPR020258" /db_xref="SubtiList:BG11470" /db_xref="UniProtKB/Swiss-Prot:Q45605" /translation="MGAIAVLFIVFGFPIVAGVFGIAGHFLFKRFWVAPLIVLITSLI LLVTLASGNSSFIFWVVMYTAIALVTSVATLFLRKFFE*" gene complement(4002960..4003208) /gene="yycQ" /locus_tag="BSU_40260" /old_locus_tag="BSU40260" CDS complement(4003224..4004387) /gene="yycP" /locus_tag="BSU_40270" /old_locus_tag="BSU40270" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 11557812, 16291680" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_391907.2" /db_xref="EnsemblGenomes-Gn:BSU40270" /db_xref="EnsemblGenomes-Tr:CAB16064" /db_xref="InterPro:IPR011047" /db_xref="SubtiList:BG11469" /db_xref="UniProtKB/Swiss-Prot:Q45606" /translation="MKKWMITIAMLILAGIALFVFISPLKSHKTVSQQDLRNPDFLDD KEVLLYFSSSADQDAFGGGKSYALFISHDGTLSSFQMKGLELGSAKVHGDSVMLEDKN TIYTIKNGLRSHKRTYQHTGDSAGFLQNTDGFYTLYNSGYDKKGDGYRSELYRQMDGE WKKDVIPYYIRASGFHDGAIYALVPTDDGKGYQLLQIQADQKKLTYLSITEWQYREGA SVESQLAVDDQAVYVMVRGQKAHDLYQMVKINKKSGEVELHDIAEYKNDEQTIYSSMP FSFKNSFFPYDGNLYFIDGFGKVHKIDAKTGKTSIVFTLSPDKMKAEFKEITQKGSSL YFFTYTYHKPAYIEQYSLKTGKKMKEKEIGKVKDVVTPKSHLKLYDVEVMKRF*" gene complement(4003224..4004387) /gene="yycP" /locus_tag="BSU_40270" /old_locus_tag="BSU40270" promotor_-10 complement(4003258..4003276) /Source="Nicolas_upshift_promotors" /id="U3171" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp=1 /psig=1 /xcortree=531 /SigmaFactorBS="cggaaagaaaatgaaagaaaaagagattggGAAGGTAAAgga tgtcgtgaCGCCGAAGAGTCATTTGAAgctgtatgatgttgaggtgatgaagaggttt t" /listShort="yycQ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(4003266) /Source="Nicolas_upshifts" /id="U3171" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp=1 /psig=1 /xcortree=531 /SigmaFactorBS="cggaaagaaaatgaaagaaaaagagattggGAAGGTAAAgga tgtcgtgaCGCCGAAGAGTCATTTGAAgctgtatgatgttgaggtgatgaagaggttt t" /listShort="yycQ" /GFF_Attribute="listLong" promotor_-35 complement(4003288..4003296) /Source="Nicolas_upshift_promotors" /id="U3171" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp=1 /psig=1 /xcortree=531 /SigmaFactorBS="cggaaagaaaatgaaagaaaaagagattggGAAGGTAAAgga tgtcgtgaCGCCGAAGAGTCATTTGAAgctgtatgatgttgaggtgatgaagaggttt t" /listShort="yycQ" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(4004398..4005135) /gene="yycO" /locus_tag="BSU_40280" /old_locus_tag="BSU40280" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 16291680" /codon_start=1 /transl_table=11 /product="conserved exported protein" /protein_id="NP_391908.1" /db_xref="EnsemblGenomes-Gn:BSU40280" /db_xref="EnsemblGenomes-Tr:CAB16065" /db_xref="SubtiList:BG11468" /db_xref="UniProtKB/Swiss-Prot:Q45607" /translation="MKLKKRVSMFLVALTMCGGLFVTPAKAVKTTNYAEEIAALQPGT TPEEIMKSASQIAKQQHVKQDVILKQFYKEITADKAEGDRLAKESGMSIMGGSSGTKK LPTSAKGNIYYTNSYTAYYNHGHVGMYSAADKIVESVPSDGVRQIAYNARDVEDNSIV QTVSVSSSQKTAAADWAVSKVGDPYSFNFVNNRNTGHDGAKNCSKLLWSAFLLKAGID IDSNGGLGVYPRDITSSSYTTTIMTIY*" gene complement(4004398..4005135) /gene="yycO" /locus_tag="BSU_40280" /old_locus_tag="BSU40280" promotor_-10 complement(4005177..4005195) /Source="Nicolas_upshift_promotors" /id="U3172" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.511488511488511" /psig="0.511488511488511" /xcortree=1227 /SigmaFactorBS="acgatttctaaaaattctgtaaataaCCTAGTTACtttcctt attttcCTAATATAATGTGGGTGAGgaaattacctttcctacactcacaagaaaagag g" /listShort="yycO, yycP, yycQ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(4005183) /Source="Nicolas_upshifts" /id="U3172" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.511488511488511" /psig="0.511488511488511" /xcortree=1227 /SigmaFactorBS="acgatttctaaaaattctgtaaataaCCTAGTTACtttcctt attttcCTAATATAATGTGGGTGAGgaaattacctttcctacactcacaagaaaagag g" /listShort="yycO, yycP, yycQ" /GFF_Attribute="listLong" promotor_-35 complement(4005209..4005217) /Source="Nicolas_upshift_promotors" /id="U3172" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.511488511488511" /psig="0.511488511488511" /xcortree=1227 /SigmaFactorBS="acgatttctaaaaattctgtaaataaCCTAGTTACtttcctt attttcCTAATATAATGTGGGTGAGgaaattacctttcctacactcacaagaaaagag g" /listShort="yycO, yycP, yycQ" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(4005277..4005747) /gene="yycN" /locus_tag="BSU_40290" /old_locus_tag="BSU40290" /EC_number="2.3.1.-" /function="16.8: Protect" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 14635137, 23944997; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative N-acetyltransferase" /protein_id="NP_391909.1" /db_xref="EnsemblGenomes-Gn:BSU40290" /db_xref="EnsemblGenomes-Tr:CAB16066" /db_xref="GOA:O32293" /db_xref="InterPro:IPR000182" /db_xref="InterPro:IPR016181" /db_xref="PDB:1ON0" /db_xref="PDB:1UFH" /db_xref="SubtiList:BG11467" /db_xref="UniProtKB/Swiss-Prot:O32293" /translation="MTIMLTPMQTEEFRSYLTYTTKHYAEEKVKAGTWLPEDAQLLSK QVFTDLLPRGLETPHHHLWSLKLNEKDIVGWLWIHAEPEHPQQEAFIYDFGLYEPYRG KGYAKQALAALDQAARSMGIRKLSLHVFAHNQTARKLYEQTGFQETDVVMSKKL*" gene complement(4005277..4005747) /gene="yycN" /locus_tag="BSU_40290" /old_locus_tag="BSU40290" downshifts complement(4005290) /Source="Nicolas_upshifts" /id="D2084" /incds=0 /nref=1 /ntot=78 /MaxReadThrough="3.78599" /MaxDrop="2.94893" /score="8.04802973" /energy="-7.6" /TU="U3175" /idTUdmin="U3174" /TUdmin=0 /isTUend="TRUE" S_feature complement(4005748..4005818) /Source="Nicolas_S_feature" /locus_tag="new_4140150_4140220_c" /HighExp="S4, S5, S6, LoTm, S3, S7, S8, B36, BT, T5.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigEF" /TUshortPSig="0.997, 0.998" /TUlongSig="NA" /TUlongPSig="NA" /label="S1549" promotor_-35 4005779..4005785 /Source="Nicolas_upshift_promotors" /id="U3173" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.551448551448551" /psig="0.995004995004995" /xcortree=3163 /SigmaFactorBS="attgtcatatcatctctccttcatatattgactagaggaTTT TACAtaaaatagaaagaGGTGTTACTATCAGAATAAGcaactgagattgataagtcac t" /listShort="rapG, phrG" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 4005799..4005818 /Source="Nicolas_upshift_promotors" /id="U3173" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.551448551448551" /psig="0.995004995004995" /xcortree=3163 /SigmaFactorBS="attgtcatatcatctctccttcatatattgactagaggaTTT TACAtaaaatagaaagaGGTGTTACTATCAGAATAAGcaactgagattgataagtcac t" /listShort="rapG, phrG" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-10 complement(4005800..4005819) /Source="Nicolas_upshift_promotors" /id="U3174" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.67032967032967" /psig="0.997002997002997" /xcortree=3164 /SigmaFactorBS="tgcgggtgcgatcttattcatgtgaaactcctttctcTAGTG ACTtatcaatctcagttGCTTATTCTGATAGTAACACctctttctattttatgtaaaa t" /listShort="S1549, yycN" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 4005800 /Source="Nicolas_upshifts" /id="U3173" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.551448551448551" /psig="0.995004995004995" /xcortree=3163 /SigmaFactorBS="attgtcatatcatctctccttcatatattgactagaggaTTT TACAtaaaatagaaagaGGTGTTACTATCAGAATAAGcaactgagattgataagtcac t" /listShort="rapG, phrG" /GFF_Attribute="listLong" upshifts complement(4005818) /Source="Nicolas_upshifts" /id="U3174" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.67032967032967" /psig="0.997002997002997" /xcortree=3164 /SigmaFactorBS="tgcgggtgcgatcttattcatgtgaaactcctttctcTAGTG ACTtatcaatctcagttGCTTATTCTGATAGTAACACctctttctattttatgtaaaa t" /listShort="S1549, yycN" /GFF_Attribute="listLong" S_feature complement(4005820..4006095) /Source="Nicolas_S_feature" /locus_tag="new_4140222_4140497_c" /HighExp="S4, S5, S6, S7, S8, S3, B36, BT, LoTm, T5.0H" /AntisenseName="rapG" /AntisenseCor="-0.20647217228472101" /AntisenseRegPval="-3.2" /CDS_PredictionProba="NA" /TUshortSig="SigEF" /TUshortPSig="0.998" /TUlongSig="NA" /TUlongPSig="NA" /label="S1550" promotor_-35 complement(4005834..4005841) /Source="Nicolas_upshift_promotors" /id="U3174" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.67032967032967" /psig="0.997002997002997" /xcortree=3164 /SigmaFactorBS="tgcgggtgcgatcttattcatgtgaaactcctttctcTAGTG ACTtatcaatctcagttGCTTATTCTGATAGTAACACctctttctattttatgtaaaa t" /listShort="S1549, yycN" /GFF_Attribute="listLong" /label="promotor_-35" CDS 4005858..4006955 /gene="rapG" /locus_tag="BSU_40300" /old_locus_tag="BSU40300" /EC_number="3.1.-.-" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:12950930, 16553878" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12950930, 16553878; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="response regulator aspartate phosphatase" /protein_id="NP_391910.1" /db_xref="EnsemblGenomes-Gn:BSU40300" /db_xref="EnsemblGenomes-Tr:CAB16067" /db_xref="GOA:O32294" /db_xref="InterPro:IPR011990" /db_xref="InterPro:IPR013026" /db_xref="InterPro:IPR019734" /db_xref="SubtiList:BG11466" /db_xref="UniProtKB/Swiss-Prot:O32294" /translation="MNKIAPAEIASMLNDWYLAIKKHEVEESSRLFEEVKPLLDDMEE DQEVLAYFSLLELRHKVLLHEARGQGFQHEEPSHMNATSDMLKYYFFLFEGMYEAYKN NYDIAIGLYKDAEQYLDNIPDPIEKAEFHLKVGKLYYKLGQNIVSLNHTRQAVKTFRE ETDYKKKLASALITMSGNFTEMSQFEEAEAYLDEAIRITSELEDHFFEAQLLHNFGLL HAQSGKSEEAVSKLEEALQNDEYARSAYYYHSAYLLIRELFKIKKKEQALSYYQDVKE KLTAEPNRICEAKIDILYAIYAEGGHAETFHLCKQHMDDLLSEKEYDSVRELSILAGE RYRELELYKEAAHFFYEALQIEELIKRTEVI*" gene 4005858..4006955 /gene="rapG" /locus_tag="BSU_40300" /old_locus_tag="BSU40300" promotor_-10 complement(4006086..4006104) /Source="Nicolas_upshift_promotors" /id="U3175" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=1127 /SigmaFactorBS="aggcctcatacatgccttcaaacagaaaaaaGTAATAtttca gcatgtcagACGTAGCATTCATATGAGAaggctcctcatgctgaaagccctgtcctct c" /listShort="S1550, S1549, yycN, yycO, yycP" /listLong="yycQ" /label="promotor_-10" upshifts complement(4006095) /Source="Nicolas_upshifts" /id="U3175" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=1127 /SigmaFactorBS="aggcctcatacatgccttcaaacagaaaaaaGTAATAtttca gcatgtcagACGTAGCATTCATATGAGAaggctcctcatgctgaaagccctgtcctct c" /listShort="S1550, S1549, yycN, yycO, yycP" /listLong="yycQ" promotor_-35 complement(4006119..4006124) /Source="Nicolas_upshift_promotors" /id="U3175" /multdbtbs="-" /comp="M3" /sig="SigEF" /pcomp="0.998001998001998" /psig="0.998001998001998" /xcortree=1127 /SigmaFactorBS="aggcctcatacatgccttcaaacagaaaaaaGTAATAtttca gcatgtcagACGTAGCATTCATATGAGAaggctcctcatgctgaaagccctgtcctct c" /listShort="S1550, S1549, yycN, yycO, yycP" /listLong="yycQ" /label="promotor_-35" promotor_-35 4006679..4006687 /Source="Nicolas_upshift_promotors" /id="U3176" /multdbtbs="SigH" /comp="M1" /sig="SigH" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=523 /SigmaFactorBS="acaggccttatcttattaccaagacgtGAAGGAAAAattgac tgctgAGCCGAATAGAATATGTGAggcaaaaatagacattttatatgccatttatgca g" /listShort="phrG" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 4006699..4006717 /Source="Nicolas_upshift_promotors" /id="U3176" /multdbtbs="SigH" /comp="M1" /sig="SigH" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=523 /SigmaFactorBS="acaggccttatcttattaccaagacgtGAAGGAAAAattgac tgctgAGCCGAATAGAATATGTGAggcaaaaatagacattttatatgccatttatgca g" /listShort="phrG" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 4006712 /Source="Nicolas_upshifts" /id="U3176" /multdbtbs="SigH" /comp="M1" /sig="SigH" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=523 /SigmaFactorBS="acaggccttatcttattaccaagacgtGAAGGAAAAattgac tgctgAGCCGAATAGAATATGTGAggcaaaaatagacattttatatgccatttatgca g" /listShort="phrG" /GFF_Attribute="listLong" CDS 4006956..4007072 /gene="phrG" /locus_tag="BSU_40310" /old_locus_tag="BSU40310" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:12950930, 16553878, 16816200" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12950930, 16553878, 16816200; Product type r: regulator" /codon_start=1 /transl_table=11 /product="secreted regulator of the activity of phosphatase RapG" /protein_id="NP_391911.1" /db_xref="EnsemblGenomes-Gn:BSU40310" /db_xref="EnsemblGenomes-Tr:CAB16068" /db_xref="InterPro:IPR030968" /db_xref="SubtiList:BG11465" /db_xref="UniProtKB/Swiss-Prot:O32295" /translation="MKRFLIGAGVAAVILSGWFIADHQTHSQEMKVAEKMIG*" gene 4006956..4007072 /gene="phrG" /locus_tag="BSU_40310" /old_locus_tag="BSU40310" downshifts 4007061 /Source="Nicolas_upshifts" /id="D2085" /incds=0 /nref=39 /ntot=249 /MaxReadThrough="4.8963" /MaxDrop="7.30713" /score="31.0184314" /energy="-13.7" /TU="U3173,U3176" /idTUdmin="U3173" /TUdmin="-45" /isTUend="FALSE" CDS complement(4007309..4008199) /gene="argI" /locus_tag="BSU_40320" /old_locus_tag="BSU40320" /EC_number="3.5.3.1" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:104957, 4216455, 7540694, 10931887, 11418582, 12533460, 22720735, 23625224, 25355936" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 104957, 4216455, 7540694, 10931887, 11418582, 12533460, 22720735, 23625224, 25355936; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="arginase" /protein_id="NP_391912.1" /db_xref="EnsemblGenomes-Gn:BSU40320" /db_xref="EnsemblGenomes-Tr:CAB16069" /db_xref="GOA:P39138" /db_xref="InterPro:IPR006035" /db_xref="InterPro:IPR014033" /db_xref="InterPro:IPR020855" /db_xref="InterPro:IPR023696" /db_xref="SubtiList:BG10932" /db_xref="UniProtKB/Swiss-Prot:P39138" /translation="MDKTISVIGMPMDLGQARRGVDMGPSAIRYAHLIERLSDMGYTV EDLGDIPINREKIKNDEELKNLNSVLAGNEKLAQKVNKVIEEKKFPLVLGGDHSIAIG TLAGTAKHYDNLGVIWYDAHGDLNTLETSPSGNIHGMPLAVSLGIGHESLVNLEGYAP KIKPENVVIIGARSLDEGERKYIKESGMKVYTMHEIDRLGMTKVIEETLDYLSACDGV HLSLDLDGLDPNDAPGVGTPVVGGISYRESHLAMEMLYDAGIITSAEFVEVNPILDHK NKTGKTAVELVESLLGKKLL*" gene complement(4007309..4008199) /gene="argI" /locus_tag="BSU_40320" /old_locus_tag="BSU40320" downshifts complement(4007315) /Source="Nicolas_upshifts" /id="D2086" /incds=0 /nref=1 /ntot=40 /MaxReadThrough="3.33097" /MaxDrop="3.38667" /score="2.36475602" /energy="-13.7" /TU="U3177" /idTUdmin="U3177" /TUdmin="-89" /isTUend="FALSE" downshifts complement(4007377) /Source="Nicolas_upshifts" /id="D2087" /incds=1 /nref=28 /ntot=201 /MaxReadThrough="5.16507" /MaxDrop="5.79932" /score="2.36475602" /energy="-13.7" /TU="U3177" /idTUdmin="U3177" /TUdmin="-151" /isTUend="FALSE" CDS complement(4008273..4009676) /gene="rocE" /locus_tag="BSU_40330" /old_locus_tag="BSU40330" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:7540694, 10648515, 15849754, 16850406, 22720735" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7540694, 10648515, 15849754, 16850406, 22720735; Product type t : transporter" /codon_start=1 /transl_table=11 /product="arginine/ornithine/gamma-aminobutyrate permease" /protein_id="NP_391913.1" /db_xref="EnsemblGenomes-Gn:BSU40330" /db_xref="EnsemblGenomes-Tr:CAB16070" /db_xref="GOA:P39137" /db_xref="InterPro:IPR002293" /db_xref="InterPro:IPR004840" /db_xref="InterPro:IPR004841" /db_xref="SubtiList:BG10933" /db_xref="UniProtKB/Swiss-Prot:P39137" /translation="MNTNQDNGNQLQRTMKSRHLFMISLGGVIGTGFFLGTGFTINQA GPLGAVLSYLVGGFIMFLTMLCLGELAVAFPVSGSFQTYATKFISPAFGFAFGWLYWL GWAVTCAIEFLSAGQLMQRWFPHIDVWIWCLVFAALMFILNAITTKAFAESEFWFSGI KILIILLFIILGGAAMFGLIDLKGGEQAPFLTHFYEDGLFPNGIKAMLITMITVNFAF QGTELIGVAAGESEDPEKTIPRSIKQTVWRTLVFFVLSIIVIAGMIPWKQAGVVESPF VAVFEQIGIPYAADIMNFVILIALLSVANSGLYASTRILYAMANEGQAFKALGKTNQR GVPMYSLIVTMAVACLSLLTKFAQAETVYMVLLSLAGMSAQVGWITISLSQIMFRRKY IREGGKIEDLKFKTPLYPVLPLIGLTLNTVVLISLAFDPEQRIALYCGVPFMIICYII YHVVIKKRQQANRQLEL*" gene complement(4008273..4009676) /gene="rocE" /locus_tag="BSU_40330" /old_locus_tag="BSU40330" S_feature complement(4009677..4009898) /Source="Nicolas_S_feature" /locus_tag="new_4144079_4144300_c" /HighExp="Lbstat, S0, LPh, T1.30H, HPh, T2.0H, LPhT, BI, M0t90, M40t90" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigL" /TUshortPSig="0.884" /TUlongSig="NA" /TUlongPSig="NA" /label="S1551" CDS complement(4009899..4011104) /gene="rocD" /locus_tag="BSU_40340" /old_locus_tag="BSU40340" /EC_number="2.6.1.13" /function="16.11: Scavenge (Catabolism)" /experiment="publication(s) with functional evidences, PMID:7540694, 9383188, 22720735, 23869754" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7540694, 9383188, 22720735, 23869754; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="ornithine aminotransferase" /protein_id="NP_391914.1" /db_xref="EnsemblGenomes-Gn:BSU40340" /db_xref="EnsemblGenomes-Tr:CAB16071" /db_xref="GOA:P38021" /db_xref="InterPro:IPR004636" /db_xref="InterPro:IPR005814" /db_xref="InterPro:IPR010164" /db_xref="InterPro:IPR015421" /db_xref="InterPro:IPR015422" /db_xref="InterPro:IPR015424" /db_xref="InterPro:IPR034757" /db_xref="SubtiList:BG10722" /db_xref="UniProtKB/Swiss-Prot:P38021" /translation="MTALSKSKEIIDQTSHYGANNYHPLPIVISEALGAWVKDPEGNE YMDMLSAYSAVNQGHRHPKIIQALKDQADKITLTSRAFHNDQLGPFYEKTAKLTGKEM ILPMNTGAEAVESAVKAARRWAYEVKGVADNQAEIIACVGNFHGRTMLAVSLSSEEEY KRGFGPMLPGIKLIPYGDVEALRQAITPNTAAFLFEPIQGEAGIVIPPEGFLQEAAAI CKEENVLFIADEIQTGLGRTGKTFACDWDGIVPDMYILGKALGGGVFPISCIAADREI LGVFNPGSHGSTFGGNPLACAVSIASLEVLEDEKLADRSLELGEYFKSELESIDSPVI KEVRGRGLFIGVELTEAARPYCERLKEEGLLCKETHDTVIRFAPPLIISKEDLDWAIE KIKHVLRNA*" gene complement(4009899..4011104) /gene="rocD" /locus_tag="BSU_40340" /old_locus_tag="BSU40340" misc_feature complement(4011161..4011179) /Source="Nicolas_upshift_promotors" /id="U3177" /multdbtbs="SigL" /comp="M18" /sig="SigL" /pcomp="0.884115884115884" /psig="0.884115884115884" /xcortree=390 /SigmaFactorBS="gcaccttgtcctcgaaaattgtagaaaacacacgaattcttg attTGGCACAGAACTTGCATTTatataaagggaaagcaggataacatgttgaaacaga a" /listShort="rocD, S1551, rocE, argI" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(4011164) /Source="Nicolas_upshifts" /id="U3177" /multdbtbs="SigL" /comp="M18" /sig="SigL" /pcomp="0.884115884115884" /psig="0.884115884115884" /xcortree=390 /SigmaFactorBS="gcaccttgtcctcgaaaattgtagaaaacacacgaattcttg attTGGCACAGAACTTGCATTTatataaagggaaagcaggataacatgttgaaacaga a" /listShort="rocD, S1551, rocE, argI" /GFF_Attribute="listLong" promotor_-35 4011274..4011279 /Source="Nicolas_upshift_promotors" /id="U3178" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.364635364635365" /psig="0.992007992007992" /xcortree=2367 /SigmaFactorBS="aaaatttcagcaagtgcaaaattctTTTGCAtatcctctccg tttTTTTATAAAATAGAAGCAATattaagaaaataattgagggaggttcatacagtgg t" /listShort="rocR" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 4011294..4011313 /Source="Nicolas_upshift_promotors" /id="U3178" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.364635364635365" /psig="0.992007992007992" /xcortree=2367 /SigmaFactorBS="aaaatttcagcaagtgcaaaattctTTTGCAtatcctctccg tttTTTTATAAAATAGAAGCAATattaagaaaataattgagggaggttcatacagtgg t" /listShort="rocR" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 4011309 /Source="Nicolas_upshifts" /id="U3178" /multdbtbs="SigA" /comp="M19" /sig="SigA" /pcomp="0.364635364635365" /psig="0.992007992007992" /xcortree=2367 /SigmaFactorBS="aaaatttcagcaagtgcaaaattctTTTGCAtatcctctccg tttTTTTATAAAATAGAAGCAATattaagaaaataattgagggaggttcatacagtgg t" /listShort="rocR" /GFF_Attribute="listLong" CDS 4011345..4012730 /gene="rocR" /locus_tag="BSU_40350" /old_locus_tag="BSU40350" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:9194709, 12533460, 12634342, 23869754" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9194709, 12533460, 12634342, 23869754; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator (NtrC/NifA family)" /protein_id="NP_391915.1" /db_xref="EnsemblGenomes-Gn:BSU40350" /db_xref="EnsemblGenomes-Tr:CAB16072" /db_xref="GOA:P38022" /db_xref="InterPro:IPR000014" /db_xref="InterPro:IPR002078" /db_xref="InterPro:IPR002197" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR009057" /db_xref="InterPro:IPR025662" /db_xref="InterPro:IPR025943" /db_xref="InterPro:IPR025944" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR035965" /db_xref="SubtiList:BG10723" /db_xref="UniProtKB/Swiss-Prot:P38022" /translation="MVKDSEFLTLVFQSILDEIDVGLHVVDEHGNTIVYNNKMMQIED MEKHDVLNKNLMDVFMFSKQQDSTLVQALQEGKTIKNVKQSYFNNKGQEITTINHTYP IVQDGKIRGAVEIAKDVTKLERLIRENMNKKGSTTYTFDSILGTSPAIQDVIENAKRA TRTSSSVLLAGETGTGKELFAQSIHNGSDRSGGPFISQNCAALPDSLVESILFGTKKG AFTGAVDQPGLFEQAHGGTLLLDEINSLNLSLQAKLLRALQERKIRRIGSTKDTPIDV RIIATMNEDPIDAIAGERMRKDLYYRLSVVTLIIPPLRERKEDILLLASEFIQKNNHL FQMNVEHISDDVKQFFLSYDWPGNIRELEHMIEGAMNFMTDEQTITASHLPYQYRMKI KPADIPEPETPRHQPAADLKEKMESFEKYVIENVLRKHGHNISKAAQELGISRQSLQY RLKKFSHSSNE*" gene 4011345..4012730 /gene="rocR" /locus_tag="BSU_40350" /old_locus_tag="BSU40350" CDS complement(4012712..4012900) /gene="yyzO" /locus_tag="BSU_40359" /old_locus_tag="BSU40359" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 17198402; Product type r: regulator" /pseudo /codon_start=1 /transl_table=11 /product="fragment of putative sensor protein" /db_xref="PSEUDO:CAX52717.1" /translation="MFDRFYKADPSRSRKYGGSGLGLAITKSIIDNHNGTIEVKSEIG RGTVFLIRLPAPDYSLDE*" gene complement(4012712..4012900) /gene="yyzO" /locus_tag="BSU_40359" /old_locus_tag="BSU40359" /pseudo CDS complement(4013017..4013145) /locus_tag="BSU_40358" /old_locus_tag="BSU40358" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_009514013.1" /translation="MPGCFDMQKKLNRGHARSVEKGYIEYEEKYKMDVTRETANGS*" gene complement(4013017..4013145) /locus_tag="BSU_40358" /old_locus_tag="BSU40358" downshifts 4013069 /Source="Nicolas_upshifts" /id="D2088" /incds=0 /nref=1 /ntot=146 /MaxReadThrough="0.86899" /MaxDrop="2.90385" /score="20.2816165" /energy="-10.8" /TU="NA" /idTUdmin="U3178" /TUdmin=110 /isTUend="FALSE" CDS complement(4013165..4014367) /gene="htrC" /locus_tag="BSU_40360" /old_locus_tag="BSU40360" /EC_number="3.4.21.-" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:10692364, 11133960, 16030236, 25384476" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10692364, 11133960, 16030236, 25384476; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="sporulation membrane serine protease" /protein_id="NP_391916.1" /db_xref="EnsemblGenomes-Gn:BSU40360" /db_xref="EnsemblGenomes-Tr:CAB16073" /db_xref="GOA:P39668" /db_xref="InterPro:IPR001478" /db_xref="InterPro:IPR001940" /db_xref="InterPro:IPR009003" /db_xref="InterPro:IPR036034" /db_xref="SubtiList:BG11054" /db_xref="UniProtKB/Swiss-Prot:P39668" /translation="MVDYEREEEHTTPEQPKRSKKGYFLSSLIGVIVGAVLMAFIMPY LSNEGLDTGALDQQQNNNGRESIRTVNVSVNNAVTKIVSNMSPAVVGVVNIQKSDIWG ESGEAGSGSGVIYKKNDHSAYVVTNHHVIEGASQIEISLKDGSRVSADLVGSDQLMDL AVLRVKSDKIKAVADFGNSDKVKSGEPVIAIGNPLGLEFAGSVTQGVISGTERAIPVD SNGDGQPDWNAEVLQTDAAINPGNSGGALLNMDGKVIGINSMKIAESAVEGIGLSIPS KLVIPVIEDLERYGKVKRPFLGIEMKSLSDIASYHWDETLKLPKNVTNGAVVMGVDAF SPAGKAGLKELDVITEFDGYKVNDIVDLRKRLYQKKVGDRVKVKFYRGGKEKSVDIKL SSADQLGS*" gene complement(4013165..4014367) /gene="htrC" /locus_tag="BSU_40360" /old_locus_tag="BSU40360" downshifts complement(4013189) /Source="Nicolas_upshifts" /id="D2089" /incds=0 /nref=134 /ntot=253 /MaxReadThrough="2.3073" /MaxDrop="5.06813" /score="5.6507537" /energy="-15" /TU="NA" /idTUdmin="U3179" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(4014399..4014410) /Source="Nicolas_upshift_promotors" /id="U3179" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.98901098901099" /psig="0.98901098901099" /xcortree=815 /SigmaFactorBS="gcgctgtataatttttctatgtaaatcaTGACTATtctagga gtttctaACCCACAATATAaccatattaacgttcttggaaaggatggaatatggtgga t" /listShort="htrC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(4014399) /Source="Nicolas_upshifts" /id="U3179" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.98901098901099" /psig="0.98901098901099" /xcortree=815 /SigmaFactorBS="gcgctgtataatttttctatgtaaatcaTGACTATtctagga gtttctaACCCACAATATAaccatattaacgttcttggaaaggatggaatatggtgga t" /listShort="htrC" /GFF_Attribute="listLong" promotor_-35 complement(4014425..4014431) /Source="Nicolas_upshift_promotors" /id="U3179" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.98901098901099" /psig="0.98901098901099" /xcortree=815 /SigmaFactorBS="gcgctgtataatttttctatgtaaatcaTGACTATtctagga gtttctaACCCACAATATAaccatattaacgttcttggaaaggatggaatatggtgga t" /listShort="htrC" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(4014449..4015243) /gene="walJ" /locus_tag="BSU_40370" /old_locus_tag="BSU40370" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 9829949, 16030236, 21169496; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative hydrolase" /protein_id="NP_391917.2" /db_xref="EnsemblGenomes-Gn:BSU40370" /db_xref="EnsemblGenomes-Tr:CAB16074" /db_xref="GOA:C0SP91" /db_xref="InterPro:IPR001279" /db_xref="InterPro:IPR036866" /db_xref="SubtiList:BG11464" /db_xref="UniProtKB/Swiss-Prot:C0SP91" /translation="MSLQFSVLASGSTGNAFYLETEDHAFLVDAGLSGKAMDGLMAQI GRKLDDVDGIFVTHEHSDHIKGLGVVARKYKLPIYANEKTWKAMENQIGKIDTDQKFV FPMETVKSFGGLDVESFGVSHDAAEPMFYVFHYSGRKLALMTDTGYVSDRMKGIIRSA NVFVFESNHDVGMLQMGRYPWSIKRRILSDVGHVSNEDAALAMTDVIGDETSRIYLAH LSQDNNMKELARMSVQQTLASKGFVTGETFDLYDTDPKKATPLCAV*" gene complement(4014449..4015243) /gene="walJ" /locus_tag="BSU_40370" /old_locus_tag="BSU40370" CDS complement(4015265..4016107) /gene="walI" /locus_tag="BSU_40380" /old_locus_tag="BSU40380" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:16030236, 17307848, 17307850, 18408157, 21219466" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16030236, 17307848, 17307850, 18408157, 21219466; Product type r: regulator" /codon_start=1 /transl_table=11 /product="regulator of WalRK" /protein_id="NP_391918.1" /db_xref="EnsemblGenomes-Gn:BSU40380" /db_xref="EnsemblGenomes-Tr:CAB16075" /db_xref="GOA:Q45612" /db_xref="InterPro:IPR018604" /db_xref="PDB:2O3O" /db_xref="SubtiList:BG11463" /db_xref="UniProtKB/Swiss-Prot:Q45612" /translation="MEWNKTKSIFIVAFLILDIFLGYQFFQKWQATGKEYEVIKNDVE HDMKADHITYEGLNKEATEGYRITANQKSFSKEEIEALKDQKPLMDMPSDDHKVTSLK MKFANPIALSKKDIEDDAQALVSSKIQDGEKYKLWKVDKSKKEIIFFQTYEGHYIYQK TDNPSNMIGQVVLHLNGKNEVVSYDQTTLETFKQIQKESLITEMDAVELLYYQNQLKE YSTVKSCKFGYVAQYPLTSTQVLAPVWRITVEYEKKVNGEKKTVQEYFTVNALESTIL DTDQ*" gene complement(4015265..4016107) /gene="walI" /locus_tag="BSU_40380" /old_locus_tag="BSU40380" CDS complement(4016094..4017461) /gene="walH" /locus_tag="BSU_40390" /old_locus_tag="BSU40390" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:16030236, 16600972, 17307850, 26999783" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16030236, 16600972, 17307850, 26999783; Product type r: regulator" /codon_start=1 /transl_table=11 /product="regulator of WalRK(YycFG)" /protein_id="NP_391919.1" /db_xref="EnsemblGenomes-Gn:BSU40390" /db_xref="EnsemblGenomes-Tr:CAB16076" /db_xref="GOA:Q794W0" /db_xref="InterPro:IPR009996" /db_xref="PDB:2FGT" /db_xref="SubtiList:BG11462" /db_xref="UniProtKB/Swiss-Prot:Q794W0" /translation="MKRENIKTILLTVLVVISLVFTWGIWTFQPNFSEGSSSTESTVR VKHKIEKTTQKLSETVRPRDMFIHDDGAHYKVDDNALYEEIWSDLPHWDVKGIKDISD QYDKAGFKSWFYGIGGSEAKLDLQFSDTIPIDIFQTLFKWSNQSFEYSSFDHILIPFN ETKANKKIYLVSYSKQLILEVTVESANYRNIMNDLKNRQSNMPAFSLFSIGSKKEFLL PNKPLTMDKKEFVTESIKTNTFKQALFSDPSIVREDSNYNNRNVLTDGISRLDVNLSQ RQVQFQQRNLVQSTSYQTGELIKKSQKYLEDTGSWTDHYQFFNINDSQQLSFYIFMDQ IPVINSTAKPFGATSAITVQWANDDILSYKRPNYSLGTNPIKTSETELMGGSEVKMLL SKQTAYDTDKIDQIFLAYQLVSTSTNDDPLVELEPVWAMKVNGKIVPITKDLLRKEGA NSGVE*" gene complement(4016094..4017461) /gene="walH" /locus_tag="BSU_40390" /old_locus_tag="BSU40390" CDS complement(4017451..4019286) /gene="walK" /locus_tag="BSU_40400" /old_locus_tag="BSU40400" /function="16.12: Sense" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:10878122, 12682299, 15015732, 15153768, 17307850, 17370266, 19019149, 22751669" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10878122, 12682299, 15015732, 15153768, 17307850, 17370266, 19019149, 22751669; Product type rc: receptor" /codon_start=1 /transl_table=11 /product="two-component sensor histidine kinase [YycG]" /protein_id="NP_391920.1" /db_xref="EnsemblGenomes-Gn:BSU40400" /db_xref="EnsemblGenomes-Tr:CAB16077" /db_xref="GOA:Q45614" /db_xref="InterPro:IPR000014" /db_xref="InterPro:IPR000700" /db_xref="InterPro:IPR001610" /db_xref="InterPro:IPR003594" /db_xref="InterPro:IPR003660" /db_xref="InterPro:IPR003661" /db_xref="InterPro:IPR004358" /db_xref="InterPro:IPR005467" /db_xref="InterPro:IPR035965" /db_xref="InterPro:IPR036097" /db_xref="InterPro:IPR036890" /db_xref="PDB:3SL2" /db_xref="SubtiList:BG11461" /db_xref="UniProtKB/Swiss-Prot:Q45614" /translation="MNKVGFFRSIQFKITLIYVLLIIIAMQIIGVYFVNQVEKSLISS YEQSLNQRIDNLSYYIEQEYKSDNDSTVIKDDVSRILNDFTKSDEVREISFVDKSYEV VGSSKPYGEEVAGKQTTDLIFKRIFSTKQSYLRKYYDPKSKIRVLISAKPVMTENQEV VGAIYVVASMEDVFNQMKTINTILASGTGLALVLTALLGIFLARTITHPLSDMRKQAM ELAKGNFSRKVKKYGHDEIGQLATTFNHLTRELEDAQAMTEGERRKLASVIAYMTDGV IATNRNGAIILLNSPALELLNVSRETALEMPITSLLGLQENYTFEDLVEQQDSMLLEI ERDDELTVLRVNFSVIQREHGKIDGLIAVIYDVTEQEKMDQERREFVANVSHELRTPL TTMRSYLEALAEGAWENKDIAPRFLMVTQNETERMIRLVNDLLQLSKFDSKDYQFNRE WIQIVRFMSLIIDRFEMTKEQHVEFIRNLPDRDLYVEIDQDKITQVLDNIISNALKYS PEGGHVTFSIDVNEEEELLYISVKDEGIGIPKKDVEKVFDRFYRVDKARTRKLGGTGL GLAIAKEMVQAHGGDIWADSIEGKGTTITFTLPYKEEQEDDWDEA*" gene complement(4017451..4019286) /gene="walK" /locus_tag="BSU_40400" /old_locus_tag="BSU40400" CDS complement(4019294..4020001) /gene="walR" /locus_tag="BSU_40410" /old_locus_tag="BSU40410" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:10878122, 12682299, 15015732, 15153768, 17307850, 17370266, 18789936, 19019149, 21219466, 23199363, 24125693, 26102633, 28674376" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10878122, 12682299, 15015732, 15153768, 17307850, 17370266, 18789936, 19019149, 21219466, 23199363, 24125693, 26102633, 28674376; Product type r: regulator" /codon_start=1 /transl_table=11 /product="two-component response regulator [YycF]" /protein_id="NP_391921.1" /db_xref="EnsemblGenomes-Gn:BSU40410" /db_xref="EnsemblGenomes-Tr:CAB16078" /db_xref="GOA:P37478" /db_xref="InterPro:IPR001789" /db_xref="InterPro:IPR001867" /db_xref="InterPro:IPR011006" /db_xref="InterPro:IPR016032" /db_xref="InterPro:IPR036388" /db_xref="PDB:2D1V" /db_xref="PDB:2ZWM" /db_xref="PDB:3F6P" /db_xref="SubtiList:BG10001" /db_xref="UniProtKB/Swiss-Prot:P37478" /translation="MDKKILVVDDEKPIADILEFNLRKEGYEVHCAHDGNEAVEMVEE LQPDLILLDIMLPNKDGVEVCREVRKKYDMPIIMLTAKDSEIDKVIGLEIGADDYVTK PFSTRELLARVKANLRRQLTTAPAEEEPSSNEIHIGSLVIFPDAYVVSKRDETIELTH REFELLHYLAKHIGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPNW IVTRRGVGYYLRNPEQD*" gene complement(4019294..4020001) /gene="walR" /locus_tag="BSU_40410" /old_locus_tag="BSU40410" S_feature complement(4020002..4020098) /Source="Nicolas_S_feature" /locus_tag="new_4154404_4154500_c" /HighExp="H2O2, G180, G150, Paraq, G135, Oxctl, dia0, LBGstat, dia5, Diami" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA, Sig-" /TUshortPSig="1, 1, 0.11" /TUlongSig="SigA" /TUlongPSig="0.986" /label="S1552" promotor_-10 complement(4020086..4020105) /Source="Nicolas_upshift_promotors" /id="U3180" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.739260739260739" /psig=1 /xcortree=2526 /SigmaFactorBS="tgaaacatgtgttttttttctaaacctttattttTTTTatct tttgaccttaaACCGTTATAATAGACAAGGAcccattctttacatgggccataagtga t" /listShort="S1552, walR, walK, walH, yycI, yycJ, htrC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(4020098) /Source="Nicolas_upshifts" /id="U3180" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.739260739260739" /psig=1 /xcortree=2526 /SigmaFactorBS="tgaaacatgtgttttttttctaaacctttattttTTTTatct tttgaccttaaACCGTTATAATAGACAAGGAcccattctttacatgggccataagtga t" /listShort="S1552, walR, walK, walH, yycI, yycJ, htrC" /GFF_Attribute="listLong" S_feature complement(4020100..4020292) /Source="Nicolas_S_feature" /locus_tag="new_4154502_4154694_c" /HighExp="G180, Paraq, Oxctl, G135, G150, H2O2, T0.30H, BMM, Cold, B60" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA, Sig-" /TUshortPSig="0.986, 1, 0.11" /TUlongSig="NA" /TUlongPSig="NA" /label="S1553" promotor_-35 complement(4020121..4020124) /Source="Nicolas_upshift_promotors" /id="U3180" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.739260739260739" /psig=1 /xcortree=2526 /SigmaFactorBS="tgaaacatgtgttttttttctaaacctttattttTTTTatct tttgaccttaaACCGTTATAATAGACAAGGAcccattctttacatgggccataagtga t" /listShort="S1552, walR, walK, walH, yycI, yycJ, htrC" /GFF_Attribute="listLong" /label="promotor_-35" upshifts complement(4020292) /Source="Nicolas_upshifts" /id="U3181" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.97902097902098" /psig="0.986013986013986" /xcortree=2753 /SigmaFactorBS="tttttcttttaggaaaaaggcaaacatgaggAGTGTTATAAT AGAAGAAAAagggagaaccggccctgcggccggttcaaagaagaagacgtcattgata a" /listShort="S1553" /listLong="S1552, walR, walK, walH, yycI, yycJ, htrC" misc_feature complement(4020302..4020321) /Source="Nicolas_upshift_promotors" /id="U3181" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.97902097902098" /psig="0.986013986013986" /xcortree=2753 /SigmaFactorBS="tttttcttttaggaaaaaggcaaacatgaggAGTGTTATAAT AGAAGAAAAagggagaaccggccctgcggccggttcaaagaagaagacgtcattgata a" /listShort="S1553" /listLong="S1552, walR, walK, walH, yycI, yycJ, htrC" /label="promotor_single_box" /note="Geneious type: promotor_single_box" downshifts complement(4020384) /Source="Nicolas_upshifts" /id="D2090" /incds=0 /nref=8 /ntot=83 /MaxReadThrough="5.21091" /MaxDrop="5.81799" /score="24.1725164" /energy="-10.6" /TU="U3183,U3184" /idTUdmin="U3181" /TUdmin="-264" /isTUend="FALSE" tRNA complement(4020385..4020457) /gene="trnY-Phe" /locus_tag="BSU_tRNA_1" /product="tRNA-Phe" /inference="profile:tRNAscan:1.23" /note="Evidence 2a: Function from experimental evidences in other organisms; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene complement(4020385..4020457) /gene="trnY-Phe" /locus_tag="BSU_tRNA_1" tRNA complement(4020493..4020569) /gene="trnY-Asp" /locus_tag="BSU_tRNA_2" /product="tRNA-Asp" /inference="profile:tRNAscan:1.23" /note="Evidence 2a: Function from experimental evidences in other organisms; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene complement(4020493..4020569) /gene="trnY-Asp" /locus_tag="BSU_tRNA_2" S_feature complement(4020570..4020650) /Source="Nicolas_S_feature" /locus_tag="new_4154972_4155052_c" /HighExp="Oxctl, Heat, BMM, Paraq, UNK1, H2O2, C30, MG 45, G180, MG 90" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, Sig-" /TUshortPSig="1, 0.11" /TUlongSig="NA" /TUlongPSig="NA" /label="S1554" tRNA complement(4020651..4020722) /gene="trnY-Glu" /locus_tag="BSU_tRNA_3" /product="tRNA-Glu" /inference="profile:tRNAscan:1.23" /note="Evidence 2a: Function from experimental evidences in other organisms; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene complement(4020651..4020722) /gene="trnY-Glu" /locus_tag="BSU_tRNA_3" tRNA complement(4020732..4020807) /gene="trnY-Lys" /locus_tag="BSU_tRNA_4" /product="tRNA-Lys" /inference="profile:tRNAscan:1.23" /note="Evidence 2a: Function from experimental evidences in other organisms; Product type n: RNA" /function="16.2: Construct biomass (Anabolism)" gene complement(4020732..4020807) /gene="trnY-Lys" /locus_tag="BSU_tRNA_4" misc_feature 4020779..4020795 /Source="Nicolas_upshift_promotors" /id="U3182" /multdbtbs="-" /comp="M20" /sig="Sig-" /pcomp="0.652347652347652" /psig="0.0739260739260739" /xcortree=1705 /SigmaFactorBS="tggtgagccatgaaggactcgaaccttcgaccctctgattaa aagtcAGATGCTCTACCAACTGagctaatggctcttaaagatgtcggaatttctatag a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 4020792 /Source="Nicolas_upshifts" /id="U3182" /multdbtbs="-" /comp="M20" /sig="Sig-" /pcomp="0.652347652347652" /psig="0.0739260739260739" /xcortree=1705 /SigmaFactorBS="tggtgagccatgaaggactcgaaccttcgaccctctgattaa aagtcAGATGCTCTACCAACTGagctaatggctcttaaagatgtcggaatttctatag a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" S_feature complement(4020808..4020904) /Source="Nicolas_S_feature" /locus_tag="new_4155210_4155306_c" /HighExp="LBGstat, C30, UNK1, Oxctl, HPh, Heat, MG 150, BMM, Paraq, MG-0.2" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, Sig-" /TUshortPSig="1, 0.11" /TUlongSig="NA" /TUlongPSig="NA" /label="S1555" promotor_-10 complement(4020888..4020907) /Source="Nicolas_upshift_promotors" /id="U3183" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.967032967032967" /psig=1 /xcortree=2627 /SigmaFactorBS="tctgagaaaaaaatatgaaaaaaaaccaaaaaagttATTGCC ACttctatttgttcgTGATATTATAAATCTCGTTGttacggaaactgcttcaatagag t" /listShort="S1555, trnY-Lys, trnY-Glu, S1554, trnY-Asp, trnY-Phe, S1553, S1552, walR, walK, walH, yycI, yycJ, htrC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(4020904) /Source="Nicolas_upshifts" /id="U3183" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.967032967032967" /psig=1 /xcortree=2627 /SigmaFactorBS="tctgagaaaaaaatatgaaaaaaaaccaaaaaagttATTGCC ACttctatttgttcgTGATATTATAAATCTCGTTGttacggaaactgcttcaatagag t" /listShort="S1555, trnY-Lys, trnY-Glu, S1554, trnY-Asp, trnY-Phe, S1553, S1552, walR, walK, walH, yycI, yycJ, htrC" /GFF_Attribute="listLong" promotor_-35 complement(4020921..4020928) /Source="Nicolas_upshift_promotors" /id="U3183" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.967032967032967" /psig=1 /xcortree=2627 /SigmaFactorBS="tctgagaaaaaaatatgaaaaaaaaccaaaaaagttATTGCC ACttctatttgttcgTGATATTATAAATCTCGTTGttacggaaactgcttcaatagag t" /listShort="S1555, trnY-Lys, trnY-Glu, S1554, trnY-Asp, trnY-Phe, S1553, S1552, walR, walK, walH, yycI, yycJ, htrC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_no_box complement(4020938..4021038) /Source="Nicolas_upshift_promotors" /id="U3184" /multdbtbs="-" /comp="M21" /sig="Sig-" /pcomp="0.587412587412587" /psig="0.10989010989011" /xcortree=285 /SigmaFactorBS="cgaactaaatagaatatgtctgcaagcccctatttaaggggc ttgtttttgtttgaaagccgcatataagttggtctgagaaaaaaatatgaaaaaaaac c" /listShort="S1555, trnY-Lys, trnY-Glu, S1554, trnY-Asp, trnY-Phe, S1553, S1552, walR, walK, walH, yycI, yycJ, htrC" /GFF_Attribute="listLong" /label="promotor_no_box" upshifts complement(4020978) /Source="Nicolas_upshifts" /id="U3184" /multdbtbs="-" /comp="M21" /sig="Sig-" /pcomp="0.587412587412587" /psig="0.10989010989011" /xcortree=285 /SigmaFactorBS="cgaactaaatagaatatgtctgcaagcccctatttaaggggc ttgtttttgtttgaaagccgcatataagttggtctgagaaaaaaatatgaaaaaaaac c" /listShort="S1555, trnY-Lys, trnY-Glu, S1554, trnY-Asp, trnY-Phe, S1553, S1552, walR, walK, walH, yycI, yycJ, htrC" /GFF_Attribute="listLong" CDS complement(4021031..4022323) /gene="purA" /locus_tag="BSU_40420" /old_locus_tag="BSU40420" /EC_number="6.3.4.4" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:1312531, 10368157, 16163456, 21424839" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1312531, 10368157, 16163456, 21424839; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="adenylosuccinate synthetase" /protein_id="NP_391922.1" /db_xref="EnsemblGenomes-Gn:BSU40420" /db_xref="EnsemblGenomes-Tr:CAB16079" /db_xref="GOA:P29726" /db_xref="InterPro:IPR001114" /db_xref="InterPro:IPR018220" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR033128" /db_xref="SubtiList:BG10002" /db_xref="UniProtKB/Swiss-Prot:P29726" /translation="MSSVVVVGTQWGDEGKGKITDFLSENAEVIARYQGGNNAGHTIK FDGITYKLHLIPSGIFYKDKTCVIGNGMVVDPKALVTELAYLHERNVSTDNLRISNRA HVILPYHLKLDEVEEERKGANKIGTTKKGIGPAYMDKAARIGIRIADLLDRDAFAEKL ERNLEEKNRLLEKMYETEGFKLEDILDEYYEYGQQIKKYVCDTSVVLNDALDEGRRVL FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPTKIKHVVGVSKAYTTRVGDGP FPTELKDEIGDQIREVGREYGTTTGRPRRVGWFDSVVVRHARRVSGITDLSLNSIDVL AGIETLKICVAYRYKGEIIEEFPASLKALAECEPVYEEMPGWTEDITGAKSLSELPEN ARHYLERVSQLTGIPLSIFSVGPDRSQTNVLRSVYRAN*" gene complement(4021031..4022323) /gene="purA" /locus_tag="BSU_40420" /old_locus_tag="BSU40420" downshifts complement(4021042) /Source="Nicolas_upshifts" /id="D2091" /incds=0 /nref=200 /ntot=241 /MaxReadThrough="2.03104" /MaxDrop="6.53551" /score="13.9967927" /energy="-10.5" /TU="NA" /idTUdmin="U3185" /TUdmin=1 /isTUend="TRUE" promotor_-10 complement(4022363..4022382) /Source="Nicolas_upshift_promotors" /id="U3185" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.932067932067932" /psig=1 /xcortree=2426 /SigmaFactorBS="acgaatatagatttacaataaattaatgttcggatttacAAT TGACTttctgtttcttcacTGATAAACTTGATTTGTTTGaatagaatcgttttgaaag g" /listShort="purA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(4022383) /Source="Nicolas_upshifts" /id="U3185" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.932067932067932" /psig=1 /xcortree=2426 /SigmaFactorBS="acgaatatagatttacaataaattaatgttcggatttacAAT TGACTttctgtttcttcacTGATAAACTTGATTTGTTTGaatagaatcgttttgaaag g" /listShort="purA" /GFF_Attribute="listLong" promotor_-35 complement(4022397..4022404) /Source="Nicolas_upshift_promotors" /id="U3185" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.932067932067932" /psig=1 /xcortree=2426 /SigmaFactorBS="acgaatatagatttacaataaattaatgttcggatttacAAT TGACTttctgtttcttcacTGATAAACTTGATTTGTTTGaatagaatcgttttgaaag g" /listShort="purA" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(4022529..4022948) /gene="yycE" /locus_tag="BSU_40430" /old_locus_tag="BSU40430" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 16731985" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_391923.1" /db_xref="EnsemblGenomes-Gn:BSU40430" /db_xref="EnsemblGenomes-Tr:CAB16080" /db_xref="InterPro:IPR004360" /db_xref="InterPro:IPR029068" /db_xref="PDB:1TWU" /db_xref="SubtiList:BG10003" /db_xref="UniProtKB/Swiss-Prot:P37479" /translation="MGKRFSSFQAAQIRIARPTGQLDEIIRFYEEGLCLKRIGEFSQH NGYDGVMFGLPHADYHLEFTQYEGGSTAPVPHPDSLLVFYVPNAVELAAITSKLKHMG YQEVESENPYWSNGGVTIEDPDGWRIVFMNSKGISGK*" gene complement(4022529..4022948) /gene="yycE" /locus_tag="BSU_40430" /old_locus_tag="BSU40430" promotor_-10 complement(4022946..4022957) /Source="Nicolas_upshift_promotors" /id="U3186" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=870 /SigmaFactorBS="acgttcgctcagcggatgaaaaattgaaagcgttttaatAAA ATGGtgcaaaaaggagatGGTAACAATATGggaaaacgtttttcgtcttttcaagcag c" /listShort="yycE" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(4022957) /Source="Nicolas_upshifts" /id="U3186" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=870 /SigmaFactorBS="acgttcgctcagcggatgaaaaattgaaagcgttttaatAAA ATGGtgcaaaaaggagatGGTAACAATATGggaaaacgtttttcgtcttttcaagcag c" /listShort="yycE" /GFF_Attribute="listLong" promotor_-35 complement(4022972..4022978) /Source="Nicolas_upshift_promotors" /id="U3186" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.997002997002997" /psig="0.997002997002997" /xcortree=870 /SigmaFactorBS="acgttcgctcagcggatgaaaaattgaaagcgttttaatAAA ATGGtgcaaaaaggagatGGTAACAATATGggaaaacgtttttcgtcttttcaagcag c" /listShort="yycE" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(4023069..4024433) /gene="dnaC" /locus_tag="BSU_40440" /old_locus_tag="BSU40440" /EC_number="3.6.4.12" /function="16.9: Replicate" /experiment="publication(s) with functional evidences, PMID:7711902, 10844689, 12682299, 12718886, 16002087, 19744498, 23563155, 25713353" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7711902, 10844689, 12682299, 12718886, 16002087, 19744498, 23563155, 25713353; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="replicative DNA helicase" /protein_id="NP_391924.2" /db_xref="EnsemblGenomes-Gn:BSU40440" /db_xref="EnsemblGenomes-Tr:CAB16081" /db_xref="GOA:P37469" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR007692" /db_xref="InterPro:IPR007693" /db_xref="InterPro:IPR007694" /db_xref="InterPro:IPR016136" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR036185" /db_xref="SubtiList:BG10004" /db_xref="UniProtKB/Swiss-Prot:P37469" /translation="MTDLLNDRLPPQNIEAEQAVLGAIFLQPSALTLASEVLIPDDFY RMSHQKIYNAMLVLGDRGEPVDLVTVTSELANTDLLEEVGGISYLTDIANSVPTAANI EYYAKIVEEKSILRRLIRTATTIAQDGYTREDEVEDLLSEAEKTIMEVAQRKNTSAFQ NIKDVLVQTYDNIEQLHNRKGDITGIPTGFTELDRMTAGFQRNDLIIVAARPSVGKTA FALNIAQNVATKTDESVAIFSLEMGAEQLVMRMLCAEGNINAQNLRTGNLTEEDWGKL TMAMGSLSNSGIYIDDTPGIRVSEIRAKCRRLKQESGLGMILIDYLQLIQGSGRSKDN RQQEVSEISRELKSIARELQVPVIALSQLSRGVEQRQDKRPMMSDIRESGSIEQDADI VAFLYRDDYYDKETENKNIIEIIIAKQRNGPVGTVSLAFVKEYNKFVNLERRFDDAGV PPGA*" gene complement(4023069..4024433) /gene="dnaC" /locus_tag="BSU_40440" /old_locus_tag="BSU40440" downshifts complement(4023089) /Source="Nicolas_upshifts" /id="D2092" /incds=0 /nref=3 /ntot=107 /MaxReadThrough="1.37092" /MaxDrop="3.96365" /score="31.6981667" /energy="-12.6" /TU="NA" /idTUdmin="U3187" /TUdmin=0 /isTUend="TRUE" downshifts complement(4023133) /Source="Nicolas_upshifts" /id="D2093" /incds=1 /nref=9 /ntot=190 /MaxReadThrough="3.89737" /MaxDrop="3.21735" /score="31.6981667" /energy="-12.6" /TU="U3187" /idTUdmin="U3190" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(4024464..4024483) /Source="Nicolas_upshift_promotors" /id="U3187" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.573426573426573" /psig=1 /xcortree=2596 /SigmaFactorBS="tctgctaactgaaaaaaacaggaaacagacaatttttcTATt ttttttctgtagaAATGGTAGAATGGAGGTTGGagattttttaatgagaggacggtgc t" /listShort="dnaC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(4024478) /Source="Nicolas_upshifts" /id="U3187" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.573426573426573" /psig=1 /xcortree=2596 /SigmaFactorBS="tctgctaactgaaaaaaacaggaaacagacaatttttcTATt ttttttctgtagaAATGGTAGAATGGAGGTTGGagattttttaatgagaggacggtgc t" /listShort="dnaC" /GFF_Attribute="listLong" promotor_-35 complement(4024498..4024500) /Source="Nicolas_upshift_promotors" /id="U3187" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.573426573426573" /psig=1 /xcortree=2596 /SigmaFactorBS="tctgctaactgaaaaaaacaggaaacagacaatttttcTATt ttttttctgtagaAATGGTAGAATGGAGGTTGGagattttttaatgagaggacggtgc t" /listShort="dnaC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 4024545..4024551 /Source="Nicolas_upshift_promotors" /id="U3188" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=184 /SigmaFactorBS="tgtctgtttcctgtttttttcagttagcagattggatCGTTT CGgacagtaacaaggcGGGAAAAATGCAATAAAACataagggaggaatgaaagatgat a" /listShort="yycD, S1556" /listLong="yycC, S1558, yycB" /label="promotor_-35" promotor_-10 4024566..4024584 /Source="Nicolas_upshift_promotors" /id="U3188" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=184 /SigmaFactorBS="tgtctgtttcctgtttttttcagttagcagattggatCGTTT CGgacagtaacaaggcGGGAAAAATGCAATAAAACataagggaggaatgaaagatgat a" /listShort="yycD, S1556" /listLong="yycC, S1558, yycB" /label="promotor_-10" upshifts 4024568 /Source="Nicolas_upshifts" /id="U3188" /multdbtbs="SigB" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=184 /SigmaFactorBS="tgtctgtttcctgtttttttcagttagcagattggatCGTTT CGgacagtaacaaggcGGGAAAAATGCAATAAAACataagggaggaatgaaagatgat a" /listShort="yycD, S1556" /listLong="yycC, S1558, yycB" CDS 4024603..4024803 /gene="yycD" /locus_tag="BSU_40450" /old_locus_tag="BSU40450" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 11717295" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_391925.1" /db_xref="EnsemblGenomes-Gn:BSU40450" /db_xref="EnsemblGenomes-Tr:CAB16082" /db_xref="InterPro:IPR018691" /db_xref="InterPro:IPR020086" /db_xref="SubtiList:BG10005" /db_xref="UniProtKB/Swiss-Prot:P37480" /translation="MIKKYAITPNVDADGWFIEVENVAPTALYTSKDAAIEKAKQVAK ENSPSKLVIYDQFKNVEEEHSF*" gene 4024603..4024803 /gene="yycD" /locus_tag="BSU_40450" /old_locus_tag="BSU40450" downshifts 4024773 /Source="Nicolas_upshifts" /id="D2094" /incds=0 /nref=15 /ntot=43 /MaxReadThrough="4.45045" /MaxDrop="5.68737" /score="12.3008592" /energy="-9.5" /TU="U3188" /idTUdmin="U3188" /TUdmin="-352" /isTUend="FALSE" S_feature 4024818..4025139 /Source="Nicolas_S_feature" /locus_tag="new_4159220_4159541" /HighExp="Etha, C30, Salt, S6, S8, M9-stat, S7, Oxctl, Paraq, Heat" /AntisenseName="yyzB" /AntisenseCor="0.309580857935493" /AntisenseRegPval="-6.7" /CDS_PredictionProba="NA" /TUshortSig="SigB" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1556" CDS complement(4024851..4025054) /gene="yyzB" /locus_tag="BSU_40460" /old_locus_tag="BSU40460" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_391926.1" /db_xref="EnsemblGenomes-Gn:BSU40460" /db_xref="EnsemblGenomes-Tr:CAB16083" /db_xref="SubtiList:BG14171" /db_xref="UniProtKB/Swiss-Prot:O32296" /translation="MHAPLSLLKQMLKEHQIDTEKAVTFEEYIAMRLKLQELMGKFAS IGEWDLYQKAADLMMHIGIQWMK*" gene complement(4024851..4025054) /gene="yyzB" /locus_tag="BSU_40460" /old_locus_tag="BSU40460" S_feature complement(4025055..4025355) /Source="Nicolas_S_feature" /locus_tag="new_4159457_4159757_c" /HighExp="S6, S8, S7, S5, S4, BT, B36, T5.0H, S3, C30" /AntisenseName="yycC" /AntisenseCor="-0.77379453158709499" /AntisenseRegPval="-54.1" /CDS_PredictionProba="NA" /TUshortSig="Sig-" /TUshortPSig="0.049" /TUlongSig="NA" /TUlongPSig="NA" /label="S1557" promotor_-35 4025120..4025123 /Source="Nicolas_upshift_promotors" /id="U3189" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.912087912087912" /psig=1 /xcortree=2150 /SigmaFactorBS="cggtcattttccgattgctctattcctttgtgacatcttCTT AcatttcacatctgaTTCTTGTACAATGGACAGAAgagaggagggatcttttgtgaga c" /listShort="yycC, S1558, yycB, yycA" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 4025138..4025157 /Source="Nicolas_upshift_promotors" /id="U3189" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.912087912087912" /psig=1 /xcortree=2150 /SigmaFactorBS="cggtcattttccgattgctctattcctttgtgacatcttCTT AcatttcacatctgaTTCTTGTACAATGGACAGAAgagaggagggatcttttgtgaga c" /listShort="yycC, S1558, yycB, yycA" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 4025141 /Source="Nicolas_upshifts" /id="U3189" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.912087912087912" /psig=1 /xcortree=2150 /SigmaFactorBS="cggtcattttccgattgctctattcctttgtgacatcttCTT AcatttcacatctgaTTCTTGTACAATGGACAGAAgagaggagggatcttttgtgaga c" /listShort="yycC, S1558, yycB, yycA" /GFF_Attribute="listLong" CDS 4025175..4025315 /gene="yycC" /locus_tag="BSU_40470" /old_locus_tag="BSU40470" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 28546427" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_391927.1" /db_xref="EnsemblGenomes-Gn:BSU40470" /db_xref="EnsemblGenomes-Tr:CAB16084" /db_xref="InterPro:IPR025550" /db_xref="SubtiList:BG10006" /db_xref="UniProtKB/Swiss-Prot:P37481" /translation="MRPLQISAETAQKLAESLNLPLEQIMHMPQHILLAKMAELQKED KS*" gene 4025175..4025315 /gene="yycC" /locus_tag="BSU_40470" /old_locus_tag="BSU40470" S_feature 4025316..4025387 /Source="Nicolas_S_feature" /locus_tag="new_4159718_4159789" /HighExp="Sw, LoTm, Gly, BC, HiOs, B60, S0, T-5.40H, LBGstat, Cold" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="SigB" /TUlongPSig=1 /label="S1558" upshifts complement(4025363) /Source="Nicolas_upshifts" /id="U3190" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.935064935064935" /psig="0.048951048951049" /xcortree=1271 /SigmaFactorBS="aaatgattggatttttttattatgtggatgtGGCAAagcagt tACTCCTCTTTTCTAAcatatacatgatattatcccgaaacaggtaagcaagtatgtg a" /listShort="S1557, yyzB, dnaC" /GFF_Attribute="listLong" promotor_-10 complement(4025366..4025380) /Source="Nicolas_upshift_promotors" /id="U3190" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.935064935064935" /psig="0.048951048951049" /xcortree=1271 /SigmaFactorBS="aaatgattggatttttttattatgtggatgtGGCAAagcagt tACTCCTCTTTTCTAAcatatacatgatattatcccgaaacaggtaagcaagtatgtg a" /listShort="S1557, yyzB, dnaC" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 complement(4025388..4025392) /Source="Nicolas_upshift_promotors" /id="U3190" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.935064935064935" /psig="0.048951048951049" /xcortree=1271 /SigmaFactorBS="aaatgattggatttttttattatgtggatgtGGCAAagcagt tACTCCTCTTTTCTAAcatatacatgatattatcccgaaacaggtaagcaagtatgtg a" /listShort="S1557, yyzB, dnaC" /GFF_Attribute="listLong" /label="promotor_-35" CDS 4025388..4026596 /gene="yycB" /locus_tag="BSU_40480" /old_locus_tag="BSU40480" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406, 25790494; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative anion ABC transporter (permease)" /protein_id="NP_391928.1" /db_xref="EnsemblGenomes-Gn:BSU40480" /db_xref="EnsemblGenomes-Tr:CAB16085" /db_xref="GOA:P37482" /db_xref="InterPro:IPR004747" /db_xref="InterPro:IPR011701" /db_xref="InterPro:IPR020846" /db_xref="InterPro:IPR036259" /db_xref="SubtiList:BG10007" /db_xref="UniProtKB/Swiss-Prot:P37482" /translation="MPHPHNKKIQSFWLITGIIFIAFNLRPAITSVGPVISSIRAELH MSNGAAGFLTALPLLSFAVLSPLAPKLGQRLGNERTLWLGLVILLIGVLTRSTGYTAA LFFGTALIGVGIAIGNVLLPSLIKHKYPEKPGIMISLYTTSMNIFAALASGVSVPLAT QMNGGWKQAFLLWGGLALLALLIWIPQLRHRDTANQTMKLQSSSIWASKMAWYVTIFM GLQSFLFYSSIAWFPEILRSHGIDTATAGWMVSLMQFASLPSTFLTPVLADRVKQQRG IVAALASVYLIGLCGLLAGGSHTLLAIWMIIIGIGQGSSISLALTLIGLRSENAQQAA ALSGMSQSFGYLLAAVGPIFVGYLFDQTHSWTMPIVLLIAALIVMGAAGQGAGRDRYI FQSEKQRNSA*" gene 4025388..4026596 /gene="yycB" /locus_tag="BSU_40480" /old_locus_tag="BSU40480" downshifts 4026577 /Source="Nicolas_upshifts" /id="D2095" /incds=0 /nref=148 /ntot=242 /MaxReadThrough="3.65611" /MaxDrop="4.91246" /score="26.443484" /energy="-10.1" /TU="U3189" /idTUdmin="U3189" /TUdmin="-484" /isTUend="FALSE" CDS 4026701..4028758 /gene="yycA" /locus_tag="BSU_40490" /old_locus_tag="BSU40490" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406, 20512483; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative glycosyl transferase" /protein_id="NP_391929.2" /db_xref="EnsemblGenomes-Gn:BSU40490" /db_xref="EnsemblGenomes-Tr:CAB16086" /db_xref="GOA:P37483" /db_xref="SubtiList:BG10008" /db_xref="UniProtKB/Swiss-Prot:P37483" /translation="MKTKRFDAALILILLAAAFLNTYHIWQDDTANQYYLAAVKSMTQ SFHNFFYASFDPSGFVTVDKPPVVLWIQTIFALIFGVHTWSVIIPQALAGVGSVFLLY RMVKPTFGVGAARIAALVMALTPIAVAVSRTNNIDSMLVFTLLLGSTCLLRAVKQGKL VWLLTAFALIGLAFNMKMMQAFMVLPAFVLFYLIASRVSLKKKIGSLLLSLVLLTGLS LSWAIAVDSASSSSRPYVGSSQTNSVLELAFGYNGTERLFGQTTGLAKGDMNAAGGGN MQNQDNMQAPNGNGSSFSQNGNQSFGNHSQAPQPPNGQTGALNGGGGTPPTGGNGPGN GGPGGGGGKSVNMFGTGDPGPLRLFQSALSGQISWMLPFSLIGLLGAIISWYRDRRGH AAKMKETLFWAAWLVPVAGFFSIAGFFHQYYLIMLAPPIAALSGIGWYTMHRLYKNNK DWSSYLLPAAVLITAVFQVYILSAYTSQIGSVWMYVLGLLGLGITLALLMLKRSHPFS KLLTIISLCVLLLTPVYWSATPLLYGGNSVLPESGPQLKGSANGGNMFSSEVDSGLLS YLRKHNTGEEYLFATLTTVTAAPYIIYENESVMAMGGFNGTDPILTVSELKKLIKEGK VKYFLLSENNSGNSELVSWIKKNGKEITSDEYSGSSSSTNSVQGMRRGPGGESQQTLY LVE*" gene 4026701..4028758 /gene="yycA" /locus_tag="BSU_40490" /old_locus_tag="BSU40490" downshifts 4028623 /Source="Nicolas_upshifts" /id="D2096" /incds=1 /nref=43 /ntot=203 /MaxReadThrough="1.96363" /MaxDrop="3.65354" /score="19.8733078" /energy="-16.6" /TU="NA" /idTUdmin="U3189" /TUdmin=1562 /isTUend="FALSE" CDS complement(4028795..4029244) /gene="rplI" /locus_tag="BSU_40500" /old_locus_tag="BSU40500" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:9000630, 9588797, 11399077, 12682299, 14586115, 23002217" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9000630, 9588797, 11399077, 12682299, 14586115, 23002217; Product type f : factor" /codon_start=1 /transl_table=11 /product="ribosomal protein L9" /protein_id="NP_391930.1" /db_xref="EnsemblGenomes-Gn:BSU40500" /db_xref="EnsemblGenomes-Tr:CAB16087" /db_xref="GOA:P37437" /db_xref="InterPro:IPR000244" /db_xref="InterPro:IPR009027" /db_xref="InterPro:IPR020069" /db_xref="InterPro:IPR020070" /db_xref="InterPro:IPR020594" /db_xref="InterPro:IPR036791" /db_xref="InterPro:IPR036935" /db_xref="SubtiList:BG10009" /db_xref="UniProtKB/Swiss-Prot:P37437" /translation="MKVIFLQDVKGKGKKGEVKNVADGYAHNFLIKKGLAVEANASNI SALNGQKQKEKKEAIAELEQAKSLKETLEKLTVELSAKSGEGGRLFGSVTSKQITEQL QKDHNIKVDKRKLELPDGIRALGYTNVPVKLHPEVQAVLKVHVKEEA*" gene complement(4028795..4029244) /gene="rplI" /locus_tag="BSU_40500" /old_locus_tag="BSU40500" downshifts complement(4028809) /Source="Nicolas_upshifts" /id="D2097" /incds=0 /nref=231 /ntot=266 /MaxReadThrough="2.69721" /MaxDrop="6.57383" /score="44.1169256" /energy="-16.6" /TU="NA" /idTUdmin="U3191" /TUdmin=0 /isTUend="TRUE" CDS complement(4029241..4031220) /gene="gdpP" /locus_tag="BSU_40510" /old_locus_tag="BSU40510" /EC_number="3.1.4.-" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:19901023, 19553197, 21257773, 21566650, 24465894, 24680501, 25616256, 26240071, 27150552, 28069645" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 19901023, 19553197, 21257773, 21566650, 24465894, 24680501, 25616256, 26240071, 27150552, 28069645; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="phosphodiesterase acting on cyclic dinucleotides" /protein_id="NP_391931.1" /db_xref="EnsemblGenomes-Gn:BSU40510" /db_xref="EnsemblGenomes-Tr:CAB16088" /db_xref="GOA:P37484" /db_xref="InterPro:IPR000160" /db_xref="InterPro:IPR001667" /db_xref="InterPro:IPR003156" /db_xref="InterPro:IPR014528" /db_xref="SubtiList:BG10010" /db_xref="UniProtKB/Swiss-Prot:P37484" /translation="MPSFYEKPLFRYPIYALIALSIITILISFYFNWILGTVEVLLLA VILFFIKRADSLIRQEIDAYISTLSYRLKKVGEEALMEMPIGIMLFNDQYYIEWANPF LSSCFNESTLVGRSLYDTCESVVPLIKQEVESETVTLNDRKFRVVIKRDERLLYFFDV TEQIQIEKLYENERTVLAYIFLDNYDDVTQGLDDQTRSTMNSQVTSLLNAWAQEYGIF LKRTSSERFIAVLNEHILTELENSKFSILDEVREKTSFDGVALTLSVGVGASVSSLKE LGDLAQSSLDLALGRGGDQVAIKLPNGKVKFYGGKTNPMEKRTRVRARVISHALKEIV TESSNVIIMGHKFPDMDSIGAAIGILKVAQANNKDGFIVIDPNQIGSSVQRLIGEIKK YEELWSRFITPEEAMEISNDDTLLVIVDTHKPSLVMEERLVNKIEHIVVIDHHRRGEE FIRDPLLVYMEPYASSTAELVTELLEYQPKRLKINMIEATALLAGIIVDTKSFSLRTG SRTFDAASYLRAKGADTVLVQKFLKETVDSYIKRAKLIQHTVLYKDNIAIASLPENEE EYFDQVLIAQAADSLLSMSEVEASFAVARRDEQTVCISARSLGEVNVQIIMEALEGGG HLTNAATQLSGISVSEALERLKHAIDEYFEGGVQR*" gene complement(4029241..4031220) /gene="gdpP" /locus_tag="BSU_40510" /old_locus_tag="BSU40510" misc_feature complement(4029722..4029741) /Source="Nicolas_upshift_promotors" /id="U3191" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.454545454545455" /psig="0.997002997002997" /xcortree=2666 /SigmaFactorBS="cgaagcgcttaaaaatcaatatgattgaagcaacagccctat taGCTGGTATAATAGTGGATACaaagagcttttctctccgcacgggctcgcggacttt c" /listShort="rplI" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(4029725) /Source="Nicolas_upshifts" /id="U3191" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.454545454545455" /psig="0.997002997002997" /xcortree=2666 /SigmaFactorBS="cgaagcgcttaaaaatcaatatgattgaagcaacagccctat taGCTGGTATAATAGTGGATACaaagagcttttctctccgcacgggctcgcggacttt c" /listShort="rplI" /GFF_Attribute="listLong" promotor_-35 4030138..4030145 /Source="Nicolas_upshift_promotors" /id="U3192" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2818 /SigmaFactorBS="acgataaaaccatctttgttatttgcctgagccacCTTTAAA AtcccgatcgctgcGCCGATAGAATCCATGTCGgggaatttatgccccatgataatca c" /listShort="S1559" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 4030159..4030177 /Source="Nicolas_upshift_promotors" /id="U3192" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2818 /SigmaFactorBS="acgataaaaccatctttgttatttgcctgagccacCTTTAAA AtcccgatcgctgcGCCGATAGAATCCATGTCGgggaatttatgccccatgataatca c" /listShort="S1559" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 4030163..4030829 /Source="Nicolas_S_feature" /locus_tag="new_4164565_4165231" /HighExp="LBGstat, C30, Cold, GM 10, GM 25, GM 15, GM-0.1, GM 45, GM 120, GM 90" /AntisenseName="yybT" /AntisenseCor="0.145393098609886" /AntisenseRegPval="-1.8" /CDS_PredictionProba="NA" /TUshortSig="SigD" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1559" upshifts 4030163 /Source="Nicolas_upshifts" /id="U3192" /multdbtbs="-" /comp="M10" /sig="SigD" /pcomp=1 /psig=1 /xcortree=2818 /SigmaFactorBS="acgataaaaccatctttgttatttgcctgagccacCTTTAAA AtcccgatcgctgcGCCGATAGAATCCATGTCGgggaatttatgccccatgataatca c" /listShort="S1559" /GFF_Attribute="listLong" CDS complement(4031257..4032186) /gene="yybS" /locus_tag="BSU_40520" /old_locus_tag="BSU40520" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406, 22956758; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative integral inner membrane protein" /protein_id="NP_391932.1" /db_xref="EnsemblGenomes-Gn:BSU40520" /db_xref="EnsemblGenomes-Tr:CAB16089" /db_xref="InterPro:IPR018710" /db_xref="SubtiList:BG10011" /db_xref="UniProtKB/Swiss-Prot:P37485" /translation="MKQTRALMEGAILISLFAIITLLVVYVPVIGTILLFALPLPMIL YTIRHGLKLGIWMGAVSLPVVFIVGSFNGLIVAFMSACAGIAMGHFFKRKEPGHAIIS GALIYMLSIVFYFVISIQFLGINIIDEAMTQYRQSLDIVETVAKQSGNAGQFEKQLKL MEEQLGIVQYLFPTAIVMVGVIFSFLSYLIAKPLLRRFSPDIPNLKPFRELKFPQSVV VLYLIIVMLSFLPLEKGQMLYSIALNGEFILGFLIFIQGLSFIFFYCHKKQYPKAAAV IAVILGFVHPVFMAAIRILGVLDMGFHIRNKVK*" gene complement(4031257..4032186) /gene="yybS" /locus_tag="BSU_40520" /old_locus_tag="BSU40520" S_feature complement(4032187..4032323) /Source="Nicolas_S_feature" /locus_tag="new_4166589_4166725_c" /HighExp="H2O2, G150, G180, Cold, Paraq, G135, Oxctl, Salt, Etha, BMM" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigB" /TUshortPSig="1, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S1560" promotor_-10 complement(4032305..4032324) /Source="Nicolas_upshift_promotors" /id="U3193" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.416583416583417" /psig=1 /xcortree=2490 /SigmaFactorBS="cttttcctttttcatgtttcacatgaaacattagcgtcaTTT TACttgcgatttggactTATGTTAAAATATAAAAGTAaaatttagagatgatataaaa a" /listShort="S1560, yybS, yybT, rplI" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(4032323) /Source="Nicolas_upshifts" /id="U3193" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.416583416583417" /psig=1 /xcortree=2490 /SigmaFactorBS="cttttcctttttcatgtttcacatgaaacattagcgtcaTTT TACttgcgatttggactTATGTTAAAATATAAAAGTAaaatttagagatgatataaaa a" /listShort="S1560, yybS, yybT, rplI" /GFF_Attribute="listLong" promotor_-35 complement(4032339..4032344) /Source="Nicolas_upshift_promotors" /id="U3193" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.416583416583417" /psig=1 /xcortree=2490 /SigmaFactorBS="cttttcctttttcatgtttcacatgaaacattagcgtcaTTT TACttgcgatttggactTATGTTAAAATATAAAAGTAaaatttagagatgatataaaa a" /listShort="S1560, yybS, yybT, rplI" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(4032413..4032562) /gene="yyzH" /locus_tag="BSU_40529" /old_locus_tag="BSU40529" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_003097802.1" /db_xref="EnsemblGenomes-Gn:BSU40529" /db_xref="EnsemblGenomes-Tr:CAX52718" /db_xref="GOA:C0H3U2" /db_xref="UniProtKB/Swiss-Prot:C0H3U2" /translation="MWDMIKNFFLFSSGVLQATTLLLVILIFMYVRKTKKKNKESSGF MDDKH*" gene complement(4032413..4032562) /gene="yyzH" /locus_tag="BSU_40529" /old_locus_tag="BSU40529" downshifts complement(4032439) /Source="Nicolas_upshifts" /id="D2098" /incds=0 /nref=1 /ntot=44 /MaxReadThrough="6.98636" /MaxDrop="3.23568" /score="-6.7107279" /energy="-8.4" /TU="U3194" /idTUdmin="U3197" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(4032601..4032620) /Source="Nicolas_upshift_promotors" /id="U3194" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=247 /SigmaFactorBS="catatcagcatatgcccaacgctcaatgttgttcatgaTGTT TTGaagtttttaaaaaGGGAAATTCACCTTATATAGgatacgggttgagaacatgcac a" /listShort="yyzH, S1560, yybS, yybT" /listLong="rplI" /label="promotor_-10" upshifts complement(4032618) /Source="Nicolas_upshifts" /id="U3194" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=247 /SigmaFactorBS="catatcagcatatgcccaacgctcaatgttgttcatgaTGTT TTGaagtttttaaaaaGGGAAATTCACCTTATATAGgatacgggttgagaacatgcac a" /listShort="yyzH, S1560, yybS, yybT" /listLong="rplI" promotor_-35 complement(4032634..4032640) /Source="Nicolas_upshift_promotors" /id="U3194" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=247 /SigmaFactorBS="catatcagcatatgcccaacgctcaatgttgttcatgaTGTT TTGaagtttttaaaaaGGGAAATTCACCTTATATAGgatacgggttgagaacatgcac a" /listShort="yyzH, S1560, yybS, yybT" /listLong="rplI" /label="promotor_-35" promotor_-35 4032641..4032650 /Source="Nicolas_upshift_promotors" /id="U3195" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1292 /SigmaFactorBS="ggtgaatttccctttttaaaaacttcaaaacaTCATGAACAA cattgagcgttgGGCATATGCTGATATGGAATctgatcgataaaggagaattttcaca t" /listShort="cotF, S1562, ppaC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 4032663..4032682 /Source="Nicolas_upshift_promotors" /id="U3195" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1292 /SigmaFactorBS="ggtgaatttccctttttaaaaacttcaaaacaTCATGAACAA cattgagcgttgGGCATATGCTGATATGGAATctgatcgataaaggagaattttcaca t" /listShort="cotF, S1562, ppaC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 4032669 /Source="Nicolas_upshifts" /id="U3195" /multdbtbs="SigK" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1292 /SigmaFactorBS="ggtgaatttccctttttaaaaacttcaaaacaTCATGAACAA cattgagcgttgGGCATATGCTGATATGGAATctgatcgataaaggagaattttcaca t" /listShort="cotF, S1562, ppaC" /GFF_Attribute="listLong" upshifts complement(4032681) /Source="Nicolas_upshifts" /id="U3196" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp=1 /psig=0 /xcortree=698 /SigmaFactorBS="tttcatgccaagccaatgttctgcgttcaTCCATgtgaaaat TCTCCTTTATCGATCagattccatatcagcatatgcccaacgctcaatgttgttcatg a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" S_feature complement(4032683..4033196) /Source="Nicolas_S_feature" /locus_tag="new_4167085_4167598_c" /HighExp="dia5, Diami, H2O2, Salt, dia15, Etha, Paraq, LPhT, G180, C30" /AntisenseName="cotF" /AntisenseCor="-0.33406696665100499" /AntisenseRegPval="-7.7" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.997" /TUlongSig="NA" /TUlongPSig="NA" /label="S1561" promotor_-10 complement(4032685..4032699) /Source="Nicolas_upshift_promotors" /id="U3196" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp=1 /psig=0 /xcortree=698 /SigmaFactorBS="tttcatgccaagccaatgttctgcgttcaTCCATgtgaaaat TCTCCTTTATCGATCagattccatatcagcatatgcccaacgctcaatgttgttcatg a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 complement(4032708..4032712) /Source="Nicolas_upshift_promotors" /id="U3196" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp=1 /psig=0 /xcortree=698 /SigmaFactorBS="tttcatgccaagccaatgttctgcgttcaTCCATgtgaaaat TCTCCTTTATCGATCagattccatatcagcatatgcccaacgctcaatgttgttcatg a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" CDS 4032708..4033190 /gene="cotF" /locus_tag="BSU_40530" /old_locus_tag="BSU40530" /function="16.13: Shape" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:1708381, 19933362, 23335421" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1708381, 19933362, 23335421; Product type s: structure" /codon_start=1 /transl_table=11 /product="spore coat protein" /protein_id="NP_391933.1" /db_xref="EnsemblGenomes-Gn:BSU40530" /db_xref="EnsemblGenomes-Tr:CAB16090" /db_xref="GOA:P23261" /db_xref="InterPro:IPR012347" /db_xref="InterPro:IPR012851" /db_xref="InterPro:IPR016493" /db_xref="SubtiList:BG10012" /db_xref="UniProtKB/Swiss-Prot:P23261" /translation="MDERRTLAWHETLEMHELVAFQSNGLIKLKKMIREVKDPQLRQL YNVSIQGVEQNLRELLPFFPQAPHREDEEEERADNPFYSGDLLGFAKTSVRSYAIAIT ETATPQLRNVLVKQLNAAIQLHAQVYRYMYQHGYYPSYNLSELLKNDVRNANRAISMK *" gene 4032708..4033190 /gene="cotF" /locus_tag="BSU_40530" /old_locus_tag="BSU40530" downshifts 4033177 /Source="Nicolas_upshifts" /id="D2099" /incds=0 /nref=20 /ntot=52 /MaxReadThrough="5.45774" /MaxDrop="4.1869" /score="-3.60126456" /energy="-16.9" /TU="U3195" /idTUdmin="U3195" /TUdmin="-1540" /isTUend="FALSE" CDS complement(4033220..4033597) /gene="hypR" /locus_tag="BSU_40540" /old_locus_tag="BSU40540" /function="16.8: Protect" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:22238377" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 22238377; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator (Cys-activated by oxidative stress)" /protein_id="NP_391934.1" /db_xref="EnsemblGenomes-Gn:BSU40540" /db_xref="EnsemblGenomes-Tr:CAB16091" /db_xref="GOA:P37486" /db_xref="InterPro:IPR002577" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="PDB:4A5M" /db_xref="PDB:4A5N" /db_xref="SubtiList:BG10013" /db_xref="UniProtKB/Swiss-Prot:P37486" /translation="MSEKKNIYPNKEGCPVEFTLDVIGGKWKGILFYHMIDGKKRFNE FRRICPSITQRMLTLQLRELEADGIVHREVYHQVPPKVEYSLTEFGRTLEPIVLQMKE WGESNRDVLESYRSNGLVKDQQK*" gene complement(4033220..4033597) /gene="hypR" /locus_tag="BSU_40540" /old_locus_tag="BSU40540" S_feature 4033222..4033751 /Source="Nicolas_S_feature" /locus_tag="new_4167624_4168153" /HighExp="S8, S6, S7, BT, S5, B36, C30, B60, G/S, Pyr" /AntisenseName="yybR" /AntisenseCor="-0.26586375565089998" /AntisenseRegPval="-5" /CDS_PredictionProba="NA" /TUshortSig="SigK" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1562" downshifts complement(4033241) /Source="Nicolas_upshifts" /id="D2100" /incds=0 /nref=124 /ntot=240 /MaxReadThrough="4.32896" /MaxDrop="5.38963" /score="10.6464065" /energy="-15.3" /TU="U3197" /idTUdmin="U3197" /TUdmin="-802" /isTUend="FALSE" promotor_-10 complement(4033652..4033671) /Source="Nicolas_upshift_promotors" /id="U3197" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.776223776223776" /psig="0.997002997002997" /xcortree=1958 /SigmaFactorBS="cccttaaaaattgatgtgaataagaagcatttTCTTTGAGct aaggagaaaagGTGTGTAAAATACTGGGTAGattagttgcaaaatgtaatgtagtatc a" /listShort="yybR, S1561, yyzH" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(4033664) /Source="Nicolas_upshifts" /id="U3197" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.776223776223776" /psig="0.997002997002997" /xcortree=1958 /SigmaFactorBS="cccttaaaaattgatgtgaataagaagcatttTCTTTGAGct aaggagaaaagGTGTGTAAAATACTGGGTAGattagttgcaaaatgtaatgtagtatc a" /listShort="yybR, S1561, yyzH" /GFF_Attribute="listLong" promotor_-35 complement(4033685..4033692) /Source="Nicolas_upshift_promotors" /id="U3197" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.776223776223776" /psig="0.997002997002997" /xcortree=1958 /SigmaFactorBS="cccttaaaaattgatgtgaataagaagcatttTCTTTGAGct aaggagaaaagGTGTGTAAAATACTGGGTAGattagttgcaaaatgtaatgtagtatc a" /listShort="yybR, S1561, yyzH" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 4033733..4033737 /Source="Nicolas_upshift_promotors" /id="U3198" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.661338661338661" /psig=1 /xcortree=2340 /SigmaFactorBS="aaatgcttcttattcacatcaatttttaagggtttgcatgAT TACacctgcagcaagaCGTGTTAAACTATATAAAGAttacactacttaaaaaaggata g" /listShort="ppaC" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 4033751..4033770 /Source="Nicolas_upshift_promotors" /id="U3198" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.661338661338661" /psig=1 /xcortree=2340 /SigmaFactorBS="aaatgcttcttattcacatcaatttttaagggtttgcatgAT TACacctgcagcaagaCGTGTTAAACTATATAAAGAttacactacttaaaaaaggata g" /listShort="ppaC" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 4033753 /Source="Nicolas_upshifts" /id="U3198" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.661338661338661" /psig=1 /xcortree=2340 /SigmaFactorBS="aaatgcttcttattcacatcaatttttaagggtttgcatgAT TACacctgcagcaagaCGTGTTAAACTATATAAAGAttacactacttaaaaaaggata g" /listShort="ppaC" /GFF_Attribute="listLong" promotor_-10 complement(4033778..4033792) /Source="Nicolas_upshift_promotors" /id="U3199" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.553446553446553" /psig="0.393606393606394" /xcortree=309 /SigmaFactorBS="tatctgggttttggtgtccgaaaataagtatctttTcCATga tagctccTATCCTTTTTTAAGTagtgtaatctttatatagtttaacacgtcttgctgc a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(4033781) /Source="Nicolas_upshifts" /id="U3199" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.553446553446553" /psig="0.393606393606394" /xcortree=309 /SigmaFactorBS="tatctgggttttggtgtccgaaaataagtatctttTcCATga tagctccTATCCTTTTTTAAGTagtgtaatctttatatagtttaacacgtcttgctgc a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" CDS 4033802..4034731 /gene="ppaC" /locus_tag="BSU_40550" /old_locus_tag="BSU40550" /EC_number="3.6.1.1" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:9782505, 12682299, 15044829, 17611193, 9782505, 21749987, 22938038" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9782505, 12682299, 15044829, 17611193, 9782505, 21749987, 22938038; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="inorganic pyrophosphatase (Mn2+-dependent)" /protein_id="NP_391935.1" /db_xref="EnsemblGenomes-Gn:BSU40550" /db_xref="EnsemblGenomes-Tr:CAB16092" /db_xref="GOA:P37487" /db_xref="InterPro:IPR001667" /db_xref="InterPro:IPR004097" /db_xref="InterPro:IPR022934" /db_xref="PDB:1K23" /db_xref="PDB:1WPM" /db_xref="PDB:1WPN" /db_xref="PDB:2HAW" /db_xref="PDB:2IW4" /db_xref="SubtiList:BG10014" /db_xref="UniProtKB/Swiss-Prot:P37487" /translation="MEKILIFGHQNPDTDTICSAIAYADLKNKLGFNAEPVRLGQVNG ETQYALDYFKQESPRLVETAANEVNGVILVDHNERQQSIKDIEEVQVLEVIDHHRIAN FETAEPLYYRAEPVGCTATILNKMYKENNVKIEKEIAGLMLSAIISDSLLFKSPTCTD QDVAAAKELAEIAGVDAEEYGLNMLKAGADLSKKTVEELISLDAKEFTLGSKKVEIAQ VNTVDIEDVKKRQAELEAVISKVVAEKNLDLFLLVITDILENDSLALAIGNEAAKVEK AFNVTLENNTALLKGVVSRKKQVVPVLTDAMAE*" gene 4033802..4034731 /gene="ppaC" /locus_tag="BSU_40550" /old_locus_tag="BSU40550" promotor_-35 complement(4033806) /Source="Nicolas_upshift_promotors" /id="U3199" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.553446553446553" /psig="0.393606393606394" /xcortree=309 /SigmaFactorBS="tatctgggttttggtgtccgaaaataagtatctttTcCATga tagctccTATCCTTTTTTAAGTagtgtaatctttatatagtttaacacgtcttgctgc a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 4034717 /Source="Nicolas_upshifts" /id="D2101" /incds=0 /nref=235 /ntot=270 /MaxReadThrough="2.06965" /MaxDrop="8.02492" /score="25.8885382" /energy="-11.7" /TU="NA" /idTUdmin="U3195" /TUdmin=0 /isTUend="TRUE" downshifts complement(4034760) /Source="Nicolas_upshifts" /id="D2102" /incds=0 /nref=14 /ntot=136 /MaxReadThrough="1.08899" /MaxDrop="4.94065" /score="19.3488922" /energy="-11.7" /TU="NA" /idTUdmin="U3200" /TUdmin=33 /isTUend="FALSE" CDS complement(4034764..4035210) /gene="yybP" /locus_tag="BSU_40560" /old_locus_tag="BSU40560" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15096624, 25794618, 25794619; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative manganese-binding lipoprotein" /protein_id="NP_391936.1" /db_xref="EnsemblGenomes-Gn:BSU40560" /db_xref="EnsemblGenomes-Tr:CAB16093" /db_xref="GOA:P37488" /db_xref="SubtiList:BG10015" /db_xref="UniProtKB/Swiss-Prot:P37488" /translation="MKIILTVLAGVGLLSAGGCGMLDQVNDGLNYTSEAAGYVEKVKT FAEEAPELAEKAVNDTEAKEKLEAQLESIQKAAADFNELTPPDAAAEIHRTIQEHNET LQKSAEDVLKQAEEGKVSLKELEQSDLVQNAKQITDVMGQIEKLGE*" gene complement(4034764..4035210) /gene="yybP" /locus_tag="BSU_40560" /old_locus_tag="BSU40560" S_feature complement(4035211..4035541) /Source="Nicolas_S_feature" /locus_tag="new_4169613_4169943_c" /HighExp="S8, Cold, S7, S6, H2O2, S5, S4, Etha, G180, G150" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.998614" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1563" misc_RNA complement(4035400..4035517) /gene="mswM" /locus_tag="BSU_misc_RNA_94" /product="manganese ion binding riboswitch" /experiment="publication(s) with functional evidences, PMID:25794618, 25794619" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 25794618, 25794619; Product type n: RNA" gene complement(4035400..4035517) /gene="mswM" /locus_tag="BSU_misc_RNA_94" promotor_-10 complement(4035532..4035551) /Source="Nicolas_upshift_promotors" /id="U3200" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.743256743256743" /psig=1 /xcortree=672 /SigmaFactorBS="cacagcgcgcttttatataaacggcaggAATTTGACtggaac agatcggTGCTTTAGAATGAAAGTAATaaaaatgaacactccaaaggggagtagcttt c" /listShort="S1563, yybP" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(4035540) /Source="Nicolas_upshifts" /id="U3200" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.743256743256743" /psig=1 /xcortree=672 /SigmaFactorBS="cacagcgcgcttttatataaacggcaggAATTTGACtggaac agatcggTGCTTTAGAATGAAAGTAATaaaaatgaacactccaaaggggagtagcttt c" /listShort="S1563, yybP" /GFF_Attribute="listLong" promotor_-35 complement(4035565..4035572) /Source="Nicolas_upshift_promotors" /id="U3200" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.743256743256743" /psig=1 /xcortree=672 /SigmaFactorBS="cacagcgcgcttttatataaacggcaggAATTTGACtggaac agatcggTGCTTTAGAATGAAAGTAATaaaaatgaacactccaaaggggagtagcttt c" /listShort="S1563, yybP" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 4035578..4035584 /Source="Nicolas_upshift_promotors" /id="U3201" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=178 /SigmaFactorBS="tttcattctaaagcaccgatctgttccagtcaaattcctgcC GTTTATataaaagcgcgctgTGGTATTTAAAATTTGAATggtttttctatcaggagat c" /listShort="yybO" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 4035597 /Source="Nicolas_upshifts" /id="U3201" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=178 /SigmaFactorBS="tttcattctaaagcaccgatctgttccagtcaaattcctgcC GTTTATataaaagcgcgctgTGGTATTTAAAATTTGAATggtttttctatcaggagat c" /listShort="yybO" /GFF_Attribute="listLong" promotor_-10 4035599..4035617 /Source="Nicolas_upshift_promotors" /id="U3201" /multdbtbs="-" /comp="M11" /sig="SigB" /pcomp=1 /psig=1 /xcortree=178 /SigmaFactorBS="tttcattctaaagcaccgatctgttccagtcaaattcctgcC GTTTATataaaagcgcgctgTGGTATTTAAAATTTGAATggtttttctatcaggagat c" /listShort="yybO" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 4035613..4035619 /Source="Nicolas_upshift_promotors" /id="U3202" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.58941058941059" /psig="0.58941058941059" /xcortree=736 /SigmaFactorBS="ttatataaaagcgcgctgtggtatttaaaattTGAATGGttt ttctatcaggaGATCATGCTATGacagaggaggttttcatcatgagtcaagagcgcgt g" /listShort="yybO" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 4035634..4035645 /Source="Nicolas_upshift_promotors" /id="U3202" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.58941058941059" /psig="0.58941058941059" /xcortree=736 /SigmaFactorBS="ttatataaaagcgcgctgtggtatttaaaattTGAATGGttt ttctatcaggaGATCATGCTATGacagaggaggttttcatcatgagtcaagagcgcgt g" /listShort="yybO" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 4035641 /Source="Nicolas_upshifts" /id="U3202" /multdbtbs="-" /comp="M8" /sig="SigGF" /pcomp="0.58941058941059" /psig="0.58941058941059" /xcortree=736 /SigmaFactorBS="ttatataaaagcgcgctgtggtatttaaaattTGAATGGttt ttctatcaggaGATCATGCTATGacagaggaggttttcatcatgagtcaagagcgcgt g" /listShort="yybO" /GFF_Attribute="listLong" CDS 4035643..4036950 /gene="yybO" /locus_tag="BSU_40570" /old_locus_tag="BSU40570" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative permease" /protein_id="NP_391937.1" /db_xref="EnsemblGenomes-Gn:BSU40570" /db_xref="EnsemblGenomes-Tr:CAB16094" /db_xref="GOA:P37489" /db_xref="InterPro:IPR011701" /db_xref="InterPro:IPR020846" /db_xref="InterPro:IPR036259" /db_xref="SubtiList:BG10016" /db_xref="UniProtKB/Swiss-Prot:P37489" /translation="MTEEVFIMSQERVKRPGHTRWYISSLLSGIIILNYFDRVAISVA APAIQDSFHLTATELGIVFSIYTYSYTLMQLPVGSLLDRFGVAWVTRVGMTIWSFLTI LLAFLQGKLLLYLFRFLIGLTSASAFPAASKATALWFPPSERGLANSLFDSAAKFSNV IGAPLVAFLVTTFDWRVAFLTIGCINVLFTIFFWQYYEQPERHKRISKSELNYIQKHN AITTEQIPYKTGPLLKKLFTNRKVWGLMIGFTGYGYTFNLLLTWLPTFFKHTYGMDLM SSGLFTAVPWLISTISGIAVGGWLVDYFIKKGYPNTKVYRTVIIVGMSFGFFFLGSIL TNNITVAIICISIGLAGISATAPVGWSISAELAPIGSVSMLSSMVNLANNLFGGIIAA SLTGYLFDVTGSFTLSFLVAGFVLLLGLVFYVFVLGDVKRIKL*" gene 4035643..4036950 /gene="yybO" /locus_tag="BSU_40570" /old_locus_tag="BSU40570" downshifts complement(4036751) /Source="Nicolas_upshifts" /id="D2103" /incds=1 /nref=1 /ntot=11 /MaxReadThrough="0.73662" /MaxDrop="2.97868" /score="30.543563" /energy="-17.9" /TU="NA" /idTUdmin="U3203" /TUdmin=264 /isTUend="FALSE" downshifts 4036939 /Source="Nicolas_upshifts" /id="D2104" /incds=0 /nref=7 /ntot=55 /MaxReadThrough="2.76545" /MaxDrop="3.99898" /score="-3.44083304" /energy="-17.9" /TU="NA" /idTUdmin="U3201" /TUdmin=0 /isTUend="TRUE" CDS complement(4036994..4037233) /gene="yyzI" /locus_tag="BSU_40573" /old_locus_tag="BSU40573" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /pseudo /codon_start=1 /transl_table=11 /product="hypothetical protein" /db_xref="PSEUDO:CAX52719.1" /translation="MNYKKQNQGFGSISGDHNDIHDILATIEENGTQDAFHYEGGLQG KNEQVLEQIEQEMLASGLDIEEQDEEKVNGDGPIL*" gene complement(4036994..4037233) /gene="yyzI" /locus_tag="BSU_40573" /old_locus_tag="BSU40573" /pseudo downshifts complement(4037015) /Source="Nicolas_upshifts" /id="D2105" /incds=0 /nref=4 /ntot=114 /MaxReadThrough="3.05613" /MaxDrop="4.69729" /score="30.543563" /energy="-17.9" /TU="NA" /idTUdmin="U3203" /TUdmin=0 /isTUend="TRUE" promotor_no_box complement(4037019..4037119) /Source="Nicolas_upshift_promotors" /id="U3203" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.552447552447552" /psig="0.010989010989011" /xcortree=1485 /SigmaFactorBS="gaaggtggtcttcaaggaaaaaacgagcaggtgctcgaacag atagagcaggaaatgctagcttcggggcttgatatagaggaacaggacgaggagaagg t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_no_box" upshifts complement(4037059) /Source="Nicolas_upshifts" /id="U3203" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.552447552447552" /psig="0.010989010989011" /xcortree=1485 /SigmaFactorBS="gaaggtggtcttcaaggaaaaaacgagcaggtgctcgaacag atagagcaggaaatgctagcttcggggcttgatatagaggaacaggacgaggagaagg t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" CDS complement(4037223..4037387) /gene="yyzJ" /locus_tag="BSU_40574" /old_locus_tag="BSU40574" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /pseudo /codon_start=1 /transl_table=11 /product="hypothetical protein" /db_xref="PSEUDO:CAX52720.1" /translation="MMIRGIHLEQQLKDIISACDVAIQNEDFDTLMNYYSERIMCKPR KQPPQRFCEL*" gene complement(4037223..4037387) /gene="yyzJ" /locus_tag="BSU_40574" /old_locus_tag="BSU40574" /pseudo CDS complement(4037399..4037584) /locus_tag="BSU_40576" /old_locus_tag="BSU40576" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="YP_009514014.1" /translation="MSHQTKYPVNEAAIMPSNRLFARFTMELSMDTEPIGASSAEMDQ RNRKNKNEKDPYVSNIV*" gene complement(4037399..4037584) /locus_tag="BSU_40576" /old_locus_tag="BSU40576" downshifts 4037665 /Source="Nicolas_upshifts" /id="D2106" /incds=0 /nref=13 /ntot=90 /MaxReadThrough="0.18425" /MaxDrop="3.85413" /score="3.91893698" /energy="-13.7" /TU="NA" /idTUdmin="U3201" /TUdmin=726 /isTUend="FALSE" CDS complement(4037857..4038003) /gene="yyzK" /locus_tag="BSU_40578" /old_locus_tag="BSU40578" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /pseudo /codon_start=1 /transl_table=11 /product="hypothetical protein" /db_xref="PSEUDO:CAX52721.1" /translation="MYGKTIKKRLEKIAFLFQEISKKRKEKIERSFVGSKQLHGLSYR RFRG*" gene complement(4037857..4038003) /gene="yyzK" /locus_tag="BSU_40578" /old_locus_tag="BSU40578" /pseudo CDS complement(4037985..4038134) /gene="yyzL" /locus_tag="BSU_40579" /old_locus_tag="BSU40579" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 5: Unknown function" /pseudo /codon_start=1 /transl_table=11 /product="hypothetical protein" /db_xref="PSEUDO:CAX52722.1" /translation="MLNQHTLTYSTIDRKDYRSYKSNPEICLRILHKINETPESRYSV CMAKP*" gene complement(4037985..4038134) /gene="yyzL" /locus_tag="BSU_40579" /old_locus_tag="BSU40579" /pseudo misc_feature complement(4038450..4038466) /Source="Nicolas_upshift_promotors" /id="U3204" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.330669330669331" /psig="0.761238761238761" /xcortree=650 /SigmaFactorBS="agattaactatattatatcttaactgtaataacctgtaaaga attttattgatagtattggATTTTATGTTATAAAGGaaaaagggtgggcgatttgctc a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(4038467) /Source="Nicolas_upshifts" /id="U3204" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.330669330669331" /psig="0.761238761238761" /xcortree=650 /SigmaFactorBS="agattaactatattatatcttaactgtaataacctgtaaaga attttattgatagtattggATTTTATGTTATAAAGGaaaaagggtgggcgatttgctc a" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 4038486..4038493 /Source="Nicolas_upshift_promotors" /id="U3205" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.955044955044955" /psig=1 /xcortree=2295 /SigmaFactorBS="ttcctttataacataaaatccaatactatcaataaaatTCTT TACAggttattacagttaAGATATAATATAGTTAATCTtttacgtaaaaggaggtttt t" /listShort="S1564, yybN, S1565, yybM, yybL, yybK, yybJ, S1567" /GFF_Attribute="listLong" /label="promotor_-35" S_feature 4038508..4038711 /Source="Nicolas_S_feature" /locus_tag="new_4172910_4173113" /HighExp="nit, T-3.40H, T-1.40H, T-0.40H, T0.0H, SMMPr, SMM, LoTm, ferm, T-4.40H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1564" promotor_-10 4038508..4038527 /Source="Nicolas_upshift_promotors" /id="U3205" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.955044955044955" /psig=1 /xcortree=2295 /SigmaFactorBS="ttcctttataacataaaatccaatactatcaataaaatTCTT TACAggttattacagttaAGATATAATATAGTTAATCTtttacgtaaaaggaggtttt t" /listShort="S1564, yybN, S1565, yybM, yybL, yybK, yybJ, S1567" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 4038508 /Source="Nicolas_upshifts" /id="U3205" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.955044955044955" /psig=1 /xcortree=2295 /SigmaFactorBS="ttcctttataacataaaatccaatactatcaataaaatTCTT TACAggttattacagttaAGATATAATATAGTTAATCTtttacgtaaaaggaggtttt t" /listShort="S1564, yybN, S1565, yybM, yybL, yybK, yybJ, S1567" /GFF_Attribute="listLong" misc_feature complement(4038529..4038543) /Source="Nicolas_upshift_promotors" /id="U3206" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.997002997002997" /psig=0 /xcortree=295 /SigmaFactorBS="tggggagatggagttactcctatttaaaacttcaacacaagt aataaaaaCCTCCTTTTACGTAAaagattaactatattatatcttaactgtaataacc t" /listShort="yyzL, yyzK" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(4038533) /Source="Nicolas_upshifts" /id="U3206" /multdbtbs="-" /comp="M15" /sig="Sig-" /pcomp="0.997002997002997" /psig=0 /xcortree=295 /SigmaFactorBS="tggggagatggagttactcctatttaaaacttcaacacaagt aataaaaaCCTCCTTTTACGTAAaagattaactatattatatcttaactgtaataacc t" /listShort="yyzL, yyzK" /GFF_Attribute="listLong" CDS 4038712..4039149 /gene="yybN" /locus_tag="BSU_40580" /old_locus_tag="BSU40580" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 27902860" /codon_start=1 /transl_table=11 /product="conserved protein of unknown function" /protein_id="NP_391938.1" /db_xref="EnsemblGenomes-Gn:BSU40580" /db_xref="EnsemblGenomes-Tr:CAB16095" /db_xref="InterPro:IPR020208" /db_xref="SubtiList:BG10017" /db_xref="UniProtKB/Swiss-Prot:P37490" /translation="MNKFLKSNFRFLLAAALGISLLASSNFIKASNDNYKFHLLVPYG YGNAYSNDAFRQTTHTDNPWKVNLQKSAEGKGTIMTFWLINTGNSKIPKASKIHNVKQ GSGAHYYHANSQGSHTYVALAVENNNYSASSYGIDGVWDEETW*" gene 4038712..4039149 /gene="yybN" /locus_tag="BSU_40580" /old_locus_tag="BSU40580" S_feature 4039150..4039226 /Source="Nicolas_S_feature" /locus_tag="new_4173552_4173628" /HighExp="M9-tran, SMMPr, MG 120, aero, GM 120, SMM, T-2.40H, T-4.40H, nit, HPh" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1565" downshifts 4039183 /Source="Nicolas_upshifts" /id="D2107" /incds=0 /nref=10 /ntot=98 /MaxReadThrough="6.91942" /MaxDrop="3.8662" /score="9.16494325" /energy="-9.5" /TU="U3205" /idTUdmin="U3201" /TUdmin=2244 /isTUend="FALSE" CDS 4039263..4040018 /gene="yybM" /locus_tag="BSU_40590" /old_locus_tag="BSU40590" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative transporter permease subunit" /protein_id="NP_391939.1" /db_xref="EnsemblGenomes-Gn:BSU40590" /db_xref="EnsemblGenomes-Tr:CAB16096" /db_xref="SubtiList:BG10018" /db_xref="UniProtKB/Swiss-Prot:P37491" /translation="MESHIYRIIKNKLTIIIFTIIILIPCVDISLLLMTNTEYHPAYA FFLSGTSVGHASQMILLWFLPLYFLLLCADDSIQDYKTGYHYILISKVGRKKYCLEKI FTSFIISFLTMFLSLILNFLLVQVFFFKGTFKNDLDQIKFPDNSLYTFSMAHPYIAIV LFSIICCIMSGFVGALGSSLSLLFRDKKYAYPASFFIWFVLILKNKSLMFLFQPFTEY GYNVLLPILCLSIFIFLIIISSIVLYEAKYNEN*" gene 4039263..4040018 /gene="yybM" /locus_tag="BSU_40590" /old_locus_tag="BSU40590" S_feature complement(4039858..4042448) /Source="Nicolas_S_feature" /locus_tag="new_4174260_4176850_c" /HighExp="S8, S6, S4, S5, S7, S3, C30, BT, G135, T5.0H" /AntisenseName="yybK" /AntisenseCor="-0.46686696237140402" /AntisenseRegPval="-15.2" /CDS_PredictionProba="NA" /TUshortSig="SigEF" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1566" CDS 4040008..4040718 /gene="yybL" /locus_tag="BSU_40600" /old_locus_tag="BSU40600" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative transporter permease subunit" /protein_id="NP_391940.1" /db_xref="EnsemblGenomes-Gn:BSU40600" /db_xref="EnsemblGenomes-Tr:CAB16097" /db_xref="SubtiList:BG10019" /db_xref="UniProtKB/Swiss-Prot:P37492" /translation="MKIKRLLLILCLLLFLVTLWFNQNHTYLGKNSIASLLYMNNSTF GYSSIFAYTLFYIVPFLMLLSNFFHSENPYKVMRMVKRKNYYKSKIMEIGFVSLLFSS IHTVINITCTHIFFSKNLLVEANFLSICLLNMISLVFFYLSVGIMFRLTYDLFNSVAL AIFIVYIILDSLYFGVKLLLPNGYWEPFRDLAIFTNMLNRYWSTSNLIIVYIRQIIIV FIFYLVGSSIFLNKDYKK*" gene 4040008..4040718 /gene="yybL" /locus_tag="BSU_40600" /old_locus_tag="BSU40600" downshifts 4040217 /Source="Nicolas_upshifts" /id="D2108" /incds=1 /nref=1 /ntot=11 /MaxReadThrough="7.39982" /MaxDrop="2.95139" /score="9.16494325" /energy="-9.5" /TU="U3205" /idTUdmin="U3205" /TUdmin="-2354" /isTUend="FALSE" CDS 4040715..4041470 /gene="yybK" /locus_tag="BSU_40610" /old_locus_tag="BSU40610" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative transporter permease subunit" /protein_id="NP_391941.1" /db_xref="EnsemblGenomes-Gn:BSU40610" /db_xref="EnsemblGenomes-Tr:CAB16098" /db_xref="InterPro:IPR024295" /db_xref="SubtiList:BG10020" /db_xref="UniProtKB/Swiss-Prot:P37493" /translation="MRIKGFFITLVAIIFQASLSSYNNNKNVFPFLDGIPISTSGHYE YQNILLWFVPIVSLSFCFSGSIRDTYISYEQLKLVREHSRVKWVTSQFLIITVVLLIF TLSQIAIFYIYSLVSLHNLDINSVINKRFVMMTLMYYLTLLNLFSFQLFMELYYKSQI AQLNISVYIIFSLILAKKLVQLNSPKVIHYFLIPNYSNGLRTGLSYYSQSGTAIIEPL LGLFIIIILQISIVILSVLKFKKIDMLKSEGLQ*" gene 4040715..4041470 /gene="yybK" /locus_tag="BSU_40610" /old_locus_tag="BSU40610" CDS 4041467..4042123 /gene="yybJ" /locus_tag="BSU_40620" /old_locus_tag="BSU40620" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 1938973; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative ATP-binding cassette subunit of transporter" /protein_id="NP_391942.1" /db_xref="EnsemblGenomes-Gn:BSU40620" /db_xref="EnsemblGenomes-Tr:CAB16099" /db_xref="GOA:P37494" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR017871" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG10021" /db_xref="UniProtKB/Swiss-Prot:P37494" /translation="MIEVLNLTKKIKKTTVLDNISYTFEKGTIYGLFGSNGSGKTMLL RALSGLIVPTEGSITIKGEQLHKDISFPKSVGLIIENMQLLPQYDAFTNLKILSKIKK IASDNDILDSISRVGLENFNSVKVSKFSLGMKQRLNIAQAIFEKPDILLLDEPTNAID EKGVAFVHDILLQEKKRGATIIITSHHKEDIISLCDIALEMNHGRLETSEKVIYKKDS *" gene 4041467..4042123 /gene="yybJ" /locus_tag="BSU_40620" /old_locus_tag="BSU40620" S_feature 4042124..4042438 /Source="Nicolas_S_feature" /locus_tag="new_4176526_4176840" /HighExp="aero, Cold, HPh, nit, M/G, M9-tran, S1, SMM, LPh, T-4.40H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1567" downshifts 4042395 /Source="Nicolas_upshifts" /id="D2109" /incds=0 /nref=93 /ntot=227 /MaxReadThrough="3.45614" /MaxDrop="4.54398" /score="2.19825508" /energy="-10.3" /TU="U3205" /idTUdmin="U3205" /TUdmin="-176" /isTUend="FALSE" downshifts 4042439 /Source="Nicolas_upshifts" /id="D2110" /incds=0 /nref=1 /ntot=3 /MaxReadThrough="2.98662" /MaxDrop="3.29879" /score="2.19825508" /energy="-10.3" /TU="U3205" /idTUdmin="U3205" /TUdmin="-132" /isTUend="FALSE" downshifts complement(4042493) /Source="Nicolas_upshifts" /id="D2111" /incds=0 /nref=1 /ntot=24 /MaxReadThrough="3.53364" /MaxDrop="2.25148" /score="10.1219981" /energy="-6.3" /TU="U3207" /idTUdmin="U3209" /TUdmin=2266 /isTUend="FALSE" CDS complement(4042498..4043286) /gene="ictI" /locus_tag="BSU_40630" /old_locus_tag="BSU40630" /function="16.8: Protect" /function="16.5: Explore" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:16321932, 22882546, 25835496" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16321932, 22882546, 25835496; Product type cp: cell process" /codon_start=1 /transl_table=11 /product="inner spore coat protein" /protein_id="NP_391943.1" /db_xref="EnsemblGenomes-Gn:BSU40630" /db_xref="EnsemblGenomes-Tr:CAB16100" /db_xref="SubtiList:BG10022" /db_xref="UniProtKB/Swiss-Prot:P37495" /translation="MNVYDIRMAPYWFYEGRGLVQHPYVFRQPVSSRAIIVSTRGDVT GDGVIDEVFLTGNQMPGSPLWRNITLVIRDGRTHQEQRIQLQNNMGYNPSLFLGDMTG DKIEDVAVVMDTGGSGGAIYAYVFAYLNRQFRRIFNSDVLNDELKYSVRYQNQYKASV ISHQQNETYILDLTYKGREYLNEIYNSQGVLKMPIEGWVNPLSGLYPVDFDRDGVYEL LAYQRIAGRYNADSLGYVQTVLKWNGQRFMFNRQTVTIFGSDLS*" gene complement(4042498..4043286) /gene="ictI" /locus_tag="BSU_40630" /old_locus_tag="BSU40630" promotor_-10 complement(4043310..4043328) /Source="Nicolas_upshift_promotors" /id="U3207" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1128 /SigmaFactorBS="gataattcatatggtacggatttaattggtgtgtaagataTG TCTTtgatgtgccattcctGCATATAATGATTCATTCAgctgattagggaaggtgaca c" /listShort="yybI, S1566" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(4043329) /Source="Nicolas_upshifts" /id="U3207" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1128 /SigmaFactorBS="gataattcatatggtacggatttaattggtgtgtaagataTG TCTTtgatgtgccattcctGCATATAATGATTCATTCAgctgattagggaaggtgaca c" /listShort="yybI, S1566" /GFF_Attribute="listLong" promotor_-35 complement(4043344..4043349) /Source="Nicolas_upshift_promotors" /id="U3207" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp=1 /psig=1 /xcortree=1128 /SigmaFactorBS="gataattcatatggtacggatttaattggtgtgtaagataTG TCTTtgatgtgccattcctGCATATAATGATTCATTCAgctgattagggaaggtgaca c" /listShort="yybI, S1566" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(4043354..4043743) /gene="yybH" /locus_tag="BSU_40640" /old_locus_tag="BSU40640" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_391944.1" /db_xref="EnsemblGenomes-Gn:BSU40640" /db_xref="EnsemblGenomes-Tr:CAB16101" /db_xref="InterPro:IPR009959" /db_xref="InterPro:IPR032710" /db_xref="PDB:2GXF" /db_xref="SubtiList:BG10023" /db_xref="UniProtKB/Swiss-Prot:P37496" /translation="MEQQLKDIISACDLAIQNEDFDTLMNYYSEDAVLVVKPGMIARG KEEIKKAFITIANYFNHHIVPTQGKMILLEAGDTVLVLSQTLLDSDKKDSEYAMERRA TYVFKKNAQGEWLCVIDNSYGTDLIGV*" gene complement(4043354..4043743) /gene="yybH" /locus_tag="BSU_40640" /old_locus_tag="BSU40640" promotor_-35 4043812..4043815 /Source="Nicolas_upshift_promotors" /id="U3208" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.544455544455544" /psig="0.999000999001" /xcortree=2554 /SigmaFactorBS="tcgctagaccactgaaaccttgaaaacaaAATGaaaagtatc cttttTTCCTATATAATCAAATAGAtatatttaacaaagtacccaagtgaaggggtga a" /listShort="yybG" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 4043830..4043849 /Source="Nicolas_upshift_promotors" /id="U3208" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.544455544455544" /psig="0.999000999001" /xcortree=2554 /SigmaFactorBS="tcgctagaccactgaaaccttgaaaacaaAATGaaaagtatc cttttTTCCTATATAATCAAATAGAtatatttaacaaagtacccaagtgaaggggtga a" /listShort="yybG" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 4043843 /Source="Nicolas_upshifts" /id="U3208" /multdbtbs="-" /comp="M7" /sig="SigA" /pcomp="0.544455544455544" /psig="0.999000999001" /xcortree=2554 /SigmaFactorBS="tcgctagaccactgaaaccttgaaaacaaAATGaaaagtatc cttttTTCCTATATAATCAAATAGAtatatttaacaaagtacccaagtgaaggggtga a" /listShort="yybG" /GFF_Attribute="listLong" CDS 4043889..4044728 /gene="yybG" /locus_tag="BSU_40650" /old_locus_tag="BSU40650" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms; PubMedId: 11709313, 12486061" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_391945.1" /db_xref="EnsemblGenomes-Gn:BSU40650" /db_xref="EnsemblGenomes-Tr:CAB16102" /db_xref="InterPro:IPR001646" /db_xref="SubtiList:BG10024" /db_xref="UniProtKB/Swiss-Prot:P37497" /translation="MSAEVTLHDNIHYDLSADCQHCFGLCCVALPYAKSADFAFDKDG GTPCRNLQSNYQCSIHKDLREKGFRGCSAYECFGAGQKVSQITYEGKDWRNSPETANQ MFDVFPIMQQLHEMLWYLHEALSIDIAKPIHSELRTTFEKIERLTRLSKERLLTLQVD EHRAEVNEWLLKTSELVRAQARHPKLPKKVSRGSVLIGAKLKGLDLRGANLRGALLIA ADLRNADLRMTDFIGADMRDADLSGADLTGSIFLTQAQVNAANGDSNTKLPLSVRTPA HWK*" gene 4043889..4044728 /gene="yybG" /locus_tag="BSU_40650" /old_locus_tag="BSU40650" downshifts 4044705 /Source="Nicolas_upshifts" /id="D2112" /incds=0 /nref=35 /ntot=188 /MaxReadThrough="1.19247" /MaxDrop="3.72166" /score="-0.156630814" /energy="-6.3" /TU="NA" /idTUdmin="U3208" /TUdmin=0 /isTUend="TRUE" CDS complement(4044761..4045975) /gene="yybF" /locus_tag="BSU_40660" /old_locus_tag="BSU40660" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 9811656, 11557812, 12486061, 15849754, 16850406; Product type t : transporter" /codon_start=1 /transl_table=11 /product="putative permease" /protein_id="NP_391946.1" /db_xref="EnsemblGenomes-Gn:BSU40660" /db_xref="EnsemblGenomes-Tr:CAB16103" /db_xref="GOA:P37498" /db_xref="InterPro:IPR011701" /db_xref="InterPro:IPR020846" /db_xref="InterPro:IPR036259" /db_xref="SubtiList:BG10025" /db_xref="UniProtKB/Swiss-Prot:P37498" /translation="MTYIRKGTPVFRKITFAFFAAGFNTFAILYCVQPLMEEFTREFH VTPTAASLSLSVTTMLLAVSMLVFGSLSEVWGRKPIMGISMLAASVLCLASAFSPSFH TLLVLRTIQGVALAGLPSIAMAYLGEEIEPGSLGSAMGLYISGNAIGAVFGRIVSGLL SEYLNWHMAMGTIGVISLIASVIFFINLPPSRHFTPRKLKLGKLGMSLIGHLRDRKLF SLFLIGFLLLGSNVALFNYIVYVLLGPPYSLNKAFSSWIFIVMIVGIFSSSFIGRMVD RYGYPKILVMNIFIVIAGALFTINNMLAVKILGIALFTFGFFGGHSVASSWVGRRALH NKAQASSLYLFFYYAGSSVFGTIGGLFWSGFHWLGVVGMITFMLLVALWLSGYLARSV KMPDKRNEKGLN*" gene complement(4044761..4045975) /gene="yybF" /locus_tag="BSU_40660" /old_locus_tag="BSU40660" downshifts complement(4044779) /Source="Nicolas_upshifts" /id="D2113" /incds=0 /nref=45 /ntot=169 /MaxReadThrough="1.92237" /MaxDrop="5.70619" /score="10.1219981" /energy="-6.3" /TU="NA" /idTUdmin="U3209" /TUdmin="-20" /isTUend="TRUE" S_feature complement(4045976..4046079) /Source="Nicolas_S_feature" /locus_tag="new_4180378_4180481_c" /HighExp="BI, B60, ferm, T0.30H, T-1.10H, T-0.40H, T-1.40H, T1.0H, nit, B36" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.94819299999999995" /TUshortSig="SigA" /TUshortPSig="0.996" /TUlongSig="NA" /TUlongPSig="NA" /label="S1568" promotor_-10 complement(4046072..4046091) /Source="Nicolas_upshift_promotors" /id="U3209" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.728271728271728" /psig="0.996003996003996" /xcortree=1589 /SigmaFactorBS="catataagcatgaaaaggatattttatatgCATTATACaaca tatatcaacGGTGCTAAGATAATAATATAaacagactcgaggatgtttgaattcgtaa g" /listShort="S1568, yybF" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 4046080..4046087 /Source="Nicolas_upshift_promotors" /id="U3210" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.627372627372627" /psig="0.997002997002997" /xcortree=2542 /SigmaFactorBS="aaacatcctcgagtctgtttatattatTATCTTAGcaccgtt gatataTGTTGTATAATGCATATAAAatatccttttcatgcttatatgtaataaggag a" /listShort="yybE" /GFF_Attribute="listLong" /label="promotor_-35" upshifts complement(4046082) /Source="Nicolas_upshifts" /id="U3209" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.728271728271728" /psig="0.996003996003996" /xcortree=1589 /SigmaFactorBS="catataagcatgaaaaggatattttatatgCATTATACaaca tatatcaacGGTGCTAAGATAATAATATAaacagactcgaggatgtttgaattcgtaa g" /listShort="S1568, yybF" /GFF_Attribute="listLong" promotor_-10 4046101..4046120 /Source="Nicolas_upshift_promotors" /id="U3210" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.627372627372627" /psig="0.997002997002997" /xcortree=2542 /SigmaFactorBS="aaacatcctcgagtctgtttatattatTATCTTAGcaccgtt gatataTGTTGTATAATGCATATAAAatatccttttcatgcttatatgtaataaggag a" /listShort="yybE" /GFF_Attribute="listLong" /label="promotor_-10" promotor_-35 complement(4046105..4046112) /Source="Nicolas_upshift_promotors" /id="U3209" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.728271728271728" /psig="0.996003996003996" /xcortree=1589 /SigmaFactorBS="catataagcatgaaaaggatattttatatgCATTATACaaca tatatcaacGGTGCTAAGATAATAATATAaacagactcgaggatgtttgaattcgtaa g" /listShort="S1568, yybF" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 4046113 /Source="Nicolas_upshifts" /id="U3210" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.627372627372627" /psig="0.997002997002997" /xcortree=2542 /SigmaFactorBS="aaacatcctcgagtctgtttatattatTATCTTAGcaccgtt gatataTGTTGTATAATGCATATAAAatatccttttcatgcttatatgtaataaggag a" /listShort="yybE" /GFF_Attribute="listLong" CDS 4046162..4047040 /gene="yybE" /locus_tag="BSU_40670" /old_locus_tag="BSU40670" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 12169591, 17526699, 22720735; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative transcriptional regulator (LysR family)" /protein_id="NP_391947.2" /db_xref="EnsemblGenomes-Gn:BSU40670" /db_xref="EnsemblGenomes-Tr:CAB16104" /db_xref="GOA:P37499" /db_xref="InterPro:IPR000847" /db_xref="InterPro:IPR005119" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG10026" /db_xref="UniProtKB/Swiss-Prot:P37499" /translation="MEWEQLEYFQTLARMQHVTKAAKSLSITQPALSRSIARLENHLG VPLFDRQGRSISLNQYGHIFLRRVQAMMKEYTEGKEEIQALLKPDQGVVSLGFLHTLG TTLVPDLIGSFQQEYPNISFQLKQNHSYWLLERLKSGDLDLCLLASIKPENPIQWIKL WSEELFVFVPNDHPLASRESITLNEIAGERFILLKKGYALRMTVDELFEKANIQPNIM FEGEEATTAAGFVAAGLGISILPDLKGLDQSKITKIRVSWPECQRVIGIAWIKGRFLS PVAETFKQYVISHFSE*" gene 4046162..4047040 /gene="yybE" /locus_tag="BSU_40670" /old_locus_tag="BSU40670" CDS 4047054..4047497 /gene="yybD" /locus_tag="BSU_40680" /old_locus_tag="BSU40680" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 28032445; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative acetyltransferase" /protein_id="NP_391948.1" /db_xref="EnsemblGenomes-Gn:BSU40680" /db_xref="EnsemblGenomes-Tr:CAB16105" /db_xref="GOA:P37500" /db_xref="InterPro:IPR000182" /db_xref="InterPro:IPR016181" /db_xref="SubtiList:BG10027" /db_xref="UniProtKB/Swiss-Prot:P37500" /translation="MNVKKITSEQDLHTAFEIRKAVFVEEQGCPISDEFDEFDTLHGD CQHILAYHQNVPVGTARVRIVGHTGKLERICILKSYRKFGLGKVIVDALERIVKEQGI SAFKLHGQTQAAGFYEKLGYRTASEEFMLDGIPHVLMTKQDDSAL*" gene 4047054..4047497 /gene="yybD" /locus_tag="BSU_40680" /old_locus_tag="BSU40680" CDS 4047580..4048059 /gene="yybC" /locus_tag="BSU_40690" /old_locus_tag="BSU40690" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406, 28032445; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative integral membrane protein" /protein_id="NP_391949.1" /db_xref="EnsemblGenomes-Gn:BSU40690" /db_xref="EnsemblGenomes-Tr:CAB16106" /db_xref="SubtiList:BG10028" /db_xref="UniProtKB/Swiss-Prot:P37501" /translation="MPANKKEGLIFGVMMCFGMVCVMSIYNAIINRAIYDFSLMTVFE MVIGFMIALLLDLLLVGPLAKKIAFRMPFDKTKKIYVILAMSTCMVIGMVLCMSVFGL VTAVLANGLNGDSLFSAYLMIVLKNFILAYPLQLLIMGPLVRGVFMKFVKPKLTAAI* " gene 4047580..4048059 /gene="yybC" /locus_tag="BSU_40690" /old_locus_tag="BSU40690" downshifts 4048049 /Source="Nicolas_upshifts" /id="D2114" /incds=0 /nref=13 /ntot=97 /MaxReadThrough="0.69144" /MaxDrop="3.55998" /score="-9.53342462" /energy="-10.9" /TU="NA" /idTUdmin="U3210" /TUdmin=1628 /isTUend="FALSE" CDS complement(4048234..4048896) /gene="yybB" /locus_tag="BSU_40700" /old_locus_tag="BSU40700" /EC_number="3.-.-.-" /function="16.11: Scavenge (Catabolism)" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative hydrolase" /protein_id="NP_391950.1" /db_xref="EnsemblGenomes-Gn:BSU40700" /db_xref="EnsemblGenomes-Tr:CAB16107" /db_xref="GOA:P37502" /db_xref="InterPro:IPR001279" /db_xref="InterPro:IPR036866" /db_xref="SubtiList:BG10029" /db_xref="UniProtKB/Swiss-Prot:P37502" /translation="MNLRQLSEHVFQCEFELDVPLRIPVHTWFIKDGDDVYIVDTGIE RFADAQIRAALAIGNPKAILLTHGHSDHIGGASKWLERFDIPIFAHQKELKYINGEEP YPNKNEVENTGVAHIVQPLTEQTLAHLPLKYYLTPGHSPGHVVYYHKIDRTLLTGDLF ITSKEDLHPPIRRFSVDINENIDSGSIIDQIKPTLICSSHGEEILYNEELYKNYVVRY RD*" gene complement(4048234..4048896) /gene="yybB" /locus_tag="BSU_40700" /old_locus_tag="BSU40700" CDS complement(4049043..4049495) /gene="yybA" /locus_tag="BSU_40710" /old_locus_tag="BSU40710" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2b: Function from indirect experimental evidences (e.g. phenotypes); PubMedId: 23504016; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional regulator (MarR family, polyamine export and degradation)" /protein_id="NP_391951.1" /db_xref="EnsemblGenomes-Gn:BSU40710" /db_xref="EnsemblGenomes-Tr:CAB16108" /db_xref="GOA:P37503" /db_xref="InterPro:IPR000835" /db_xref="InterPro:IPR023187" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="SubtiList:BG10030" /db_xref="UniProtKB/Swiss-Prot:P37503" /translation="MNDILREIGMIARALDSISNIEFKDLDLTRGQYLYLVRIYENPG IIQEKLAEMIKVDRTTAARAIKKLEMQGFIQKLPDEQNKKIKKLFPTEKGKKVYPLLR REGEHSTEVALSGFTSEEKETISALLHRVRKNIERDWEYVKKGNKRDY*" gene complement(4049043..4049495) /gene="yybA" /locus_tag="BSU_40710" /old_locus_tag="BSU40710" promotor_-35 4049519..4049526 /Source="Nicolas_upshift_promotors" /id="U3211" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.706293706293706" /psig="0.998001998001998" /xcortree=1783 /SigmaFactorBS="aaatatcattcattcctaaaacccctcacgtattttTGTTGC AAttacaacaaaaatgTTTTAACCTTACTATTATAAgaccacatgcgtgctgtacagt c" /listShort="S1569, yyaT, yyaS" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 4049541..4049560 /Source="Nicolas_upshift_promotors" /id="U3211" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.706293706293706" /psig="0.998001998001998" /xcortree=1783 /SigmaFactorBS="aaatatcattcattcctaaaacccctcacgtattttTGTTGC AAttacaacaaaaatgTTTTAACCTTACTATTATAAgaccacatgcgtgctgtacagt c" /listShort="S1569, yyaT, yyaS" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 4049543 /Source="Nicolas_upshifts" /id="U3211" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.706293706293706" /psig="0.998001998001998" /xcortree=1783 /SigmaFactorBS="aaatatcattcattcctaaaacccctcacgtattttTGTTGC AAttacaacaaaaatgTTTTAACCTTACTATTATAAgaccacatgcgtgctgtacagt c" /listShort="S1569, yyaT, yyaS" /GFF_Attribute="listLong" S_feature 4049545..4049614 /Source="Nicolas_S_feature" /locus_tag="new_4183947_4184016" /HighExp="G135, G180, H2O2, LoTm, G150, Salt, Diami, Paraq, LBGstat, HiTm" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.998" /TUlongSig="NA" /TUlongPSig="NA" /label="S1569" promotor_-10 complement(4049548..4049567) /Source="Nicolas_upshift_promotors" /id="U3212" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.481518481518482" /psig="0.992007992007992" /xcortree=2273 /SigmaFactorBS="aatcaatccttttctgatattagTCTGGACTgtacagcacgc aTGTGGTCTTATAATAGTAAGgttaaaacatttttgttgtaattgcaacaaaaatacg t" /listShort="yybA, yybB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(4049550) /Source="Nicolas_upshifts" /id="U3212" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.481518481518482" /psig="0.992007992007992" /xcortree=2273 /SigmaFactorBS="aatcaatccttttctgatattagTCTGGACTgtacagcacgc aTGTGGTCTTATAATAGTAAGgttaaaacatttttgttgtaattgcaacaaaaatacg t" /listShort="yybA, yybB" /GFF_Attribute="listLong" promotor_-35 complement(4049580..4049587) /Source="Nicolas_upshift_promotors" /id="U3212" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.481518481518482" /psig="0.992007992007992" /xcortree=2273 /SigmaFactorBS="aatcaatccttttctgatattagTCTGGACTgtacagcacgc aTGTGGTCTTATAATAGTAAGgttaaaacatttttgttgtaattgcaacaaaaatacg t" /listShort="yybA, yybB" /GFF_Attribute="listLong" /label="promotor_-35" CDS 4049615..4050061 /gene="yyaT" /locus_tag="BSU_40720" /old_locus_tag="BSU40720" /EC_number="2.3.1.-" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 23944997; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative acetyltransferase (polyamine degradation)" /protein_id="NP_391952.1" /db_xref="EnsemblGenomes-Gn:BSU40720" /db_xref="EnsemblGenomes-Tr:CAB16109" /db_xref="GOA:P37504" /db_xref="InterPro:IPR000182" /db_xref="InterPro:IPR016181" /db_xref="SubtiList:BG10031" /db_xref="UniProtKB/Swiss-Prot:P37504" /translation="MNIKRITTEADLHEALKIRRGVFIEEQHVSEADEFDEFDTLQEQ CQHILVYHENQPVGTGRARIVGHTAKLERICILKPYRKYGLGKIIVSGLEEIMKEKGL TSYKLHGQTQAAGFYQKLGYQISSQEFMEDGIPHVLMTKEISRNIT*" gene 4049615..4050061 /gene="yyaT" /locus_tag="BSU_40720" /old_locus_tag="BSU40720" CDS 4050058..4050663 /gene="yyaS" /locus_tag="BSU_40730" /old_locus_tag="BSU40730" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406, 23504016; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative integral inner membrane protein" /protein_id="NP_391953.1" /db_xref="EnsemblGenomes-Gn:BSU40730" /db_xref="EnsemblGenomes-Tr:CAB16110" /db_xref="SubtiList:BG10032" /db_xref="UniProtKB/Swiss-Prot:P37505" /translation="MKYMYYGIGILILSLGISLTIQSGLGTSPFDALLVGLSKKIGLT VGSWEVLISVILLICNAILTRKKPILLGLITAFITGIGIDLWLFVVKNTIYLNSLLSK LICFGIGLVLIGLGTAIYLQTKFASTPIDHLTLIIRDLSKRTILFSRTLVYALFLVLA IIFKGPIGIGTLLTVCLGGMLLHVFMPIVERHFLSKNRRGY*" gene 4050058..4050663 /gene="yyaS" /locus_tag="BSU_40730" /old_locus_tag="BSU40730" CDS complement(4050758..4051279) /gene="yyaR" /locus_tag="BSU_40740" /old_locus_tag="BSU40740" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 16579456, 23944997; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative acetyl-transferase" /protein_id="NP_391954.1" /db_xref="EnsemblGenomes-Gn:BSU40740" /db_xref="EnsemblGenomes-Tr:CAB16111" /db_xref="GOA:P37506" /db_xref="InterPro:IPR000182" /db_xref="InterPro:IPR008125" /db_xref="InterPro:IPR016181" /db_xref="SubtiList:BG10033" /db_xref="UniProtKB/Swiss-Prot:P37506" /translation="MIMKMTHLNMKDFNKPNEPFVVFGRMIPAFENGVWTYTEERFSK PYFKQYEDDDMDVSYVEEEGKAAFLYYLENNCIGRIKIRSNWNGYALIEDIAVAKDYR KKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFIIGAVDTMLYSNFP TANEIAIFWYYKF*" gene complement(4050758..4051279) /gene="yyaR" /locus_tag="BSU_40740" /old_locus_tag="BSU40740" S_feature complement(4051280..4052107) /Source="Nicolas_S_feature" /locus_tag="new_4185682_4186509_c" /HighExp="T0.30H, Lbstat, H2O2, LPhT, T1.0H, dia15, Diami, T1.30H, dia5, M9-stat" /AntisenseName="yyaQ" /AntisenseCor="0.51412050904654805" /AntisenseRegPval="-18.8" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.997" /TUlongSig="NA" /TUlongPSig="NA" /label="S1570" promotor_-35 4051328..4051335 /Source="Nicolas_upshift_promotors" /id="U3213" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.667332667332667" /psig="0.955044955044955" /xcortree=607 /SigmaFactorBS="cgccaatcgagataatatttagtaaactcgtttcgatacTAT TCAACaacagcttccaaaaGTGTACTCTTTAAGAGAACAgcattagataaggcatcca t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 4051349 /Source="Nicolas_upshifts" /id="U3213" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.667332667332667" /psig="0.955044955044955" /xcortree=607 /SigmaFactorBS="cgccaatcgagataatatttagtaaactcgtttcgatacTAT TCAACaacagcttccaaaaGTGTACTCTTTAAGAGAACAgcattagataaggcatcca t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 4051350..4051369 /Source="Nicolas_upshift_promotors" /id="U3213" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.667332667332667" /psig="0.955044955044955" /xcortree=607 /SigmaFactorBS="cgccaatcgagataatatttagtaaactcgtttcgatacTAT TCAACaacagcttccaaaaGTGTACTCTTTAAGAGAACAgcattagataaggcatcca t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" S_feature 4051415..4051689 /Source="Nicolas_S_feature" /locus_tag="new_4185817_4186091" /HighExp="LBGstat, G135, BC, G180, Sw, M9-stat, Diami, T0.30H, H2O2, G150" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="0.13713" /TUshortSig="SigA" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S1571" upshifts 4051415 /Source="Nicolas_upshifts" /id="U3214" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.974025974025974" /psig="0.999000999001" /xcortree=2754 /SigmaFactorBS="ctctttaagagaacagcattagataaggcatccattacctta tatatttcactatcttaatgaGGTATTtcaacagaggctTGTGGTACAGTAAAAAGGA A" /listShort="S1571, yyaQ, S1572, yyaP" /GFF_Attribute="listLong" promotor_-35 4051418..4051423 /Source="Nicolas_upshift_promotors" /id="U3214" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.974025974025974" /psig="0.999000999001" /xcortree=2754 /SigmaFactorBS="ctctttaagagaacagcattagataaggcatccattacctta tatatttcactatcttaatgaGGTATTtcaacagaggctTGTGGTACAGTAAAAAGGA A" /listShort="S1571, yyaQ, S1572, yyaP" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 4051436..4051455 /Source="Nicolas_upshift_promotors" /id="U3214" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.974025974025974" /psig="0.999000999001" /xcortree=2754 /SigmaFactorBS="ctctttaagagaacagcattagataaggcatccattacctta tatatttcactatcttaatgaGGTATTtcaacagaggctTGTGGTACAGTAAAAAGGA A" /listShort="S1571, yyaQ, S1572, yyaP" /GFF_Attribute="listLong" /label="promotor_-10" CDS 4051690..4052046 /gene="yyaQ" /locus_tag="BSU_40750" /old_locus_tag="BSU40750" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_391955.1" /db_xref="EnsemblGenomes-Gn:BSU40750" /db_xref="EnsemblGenomes-Tr:CAB16112" /db_xref="InterPro:IPR007351" /db_xref="SubtiList:BG10034" /db_xref="UniProtKB/Swiss-Prot:P37507" /translation="MLTREDIFKHVKEKYGTSPDYPWEKYPNYASLRHTSNKKWYGLI MNVLPEKLGLDGHGEIDILNLKCPPEISDRLRNGENILPGYHMDKEHWISIVLERTDP EGEIYNLIEQSFHLTK*" gene 4051690..4052046 /gene="yyaQ" /locus_tag="BSU_40750" /old_locus_tag="BSU40750" S_feature 4052047..4052205 /Source="Nicolas_S_feature" /locus_tag="new_4186449_4186607" /HighExp="Sw, BC, G135, H2O2, LBGstat, G180, LPhT, T0.30H, Diami, dia15" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S1572" promotor_-10 complement(4052089..4052108) /Source="Nicolas_upshift_promotors" /id="U3215" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.942057942057942" /psig="0.997002997002997" /xcortree=621 /SigmaFactorBS="cttctcccactctcgcaccagatgaactaagttgcgtTTGTG GACagagtgaagaacagTATCCTAAAATGAAAGTGCCcactactcttcgcagcttgat t" /listShort="S1570, yyaR" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(4052107) /Source="Nicolas_upshifts" /id="U3215" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.942057942057942" /psig="0.997002997002997" /xcortree=621 /SigmaFactorBS="cttctcccactctcgcaccagatgaactaagttgcgtTTGTG GACagagtgaagaacagTATCCTAAAATGAAAGTGCCcactactcttcgcagcttgat t" /listShort="S1570, yyaR" /GFF_Attribute="listLong" promotor_-35 complement(4052123..4052130) /Source="Nicolas_upshift_promotors" /id="U3215" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.942057942057942" /psig="0.997002997002997" /xcortree=621 /SigmaFactorBS="cttctcccactctcgcaccagatgaactaagttgcgtTTGTG GACagagtgaagaacagTATCCTAAAATGAAAGTGCCcactactcttcgcagcttgat t" /listShort="S1570, yyaR" /GFF_Attribute="listLong" /label="promotor_-35" CDS 4052206..4052772 /gene="yyaP" /locus_tag="BSU_40760" /old_locus_tag="BSU40760" /EC_number="1.-.-.-" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative oxidoreductase" /protein_id="NP_391956.1" /db_xref="EnsemblGenomes-Gn:BSU40760" /db_xref="EnsemblGenomes-Tr:CAB16113" /db_xref="GOA:P37508" /db_xref="InterPro:IPR002734" /db_xref="InterPro:IPR024072" /db_xref="PDB:2GD9" /db_xref="SubtiList:BG10035" /db_xref="UniProtKB/Swiss-Prot:P37508" /translation="MTNNLKQRRIILDLAVTLDGFIEGKNGEVDWCIMDPDMGFTDFL NQIDTILYGRKSFDLWGQYIPKNEDPDTEKELWKLVHSKKKYVFSRTQNEIDNQAIFI NDNILEEVNKLKKNPGKDIWLYGGASLITTFINLGLVDEFRLSIHPVVLGEGKPLFID VKQRINLKMVNTRTFSSGVVQIVYHWNG*" gene 4052206..4052772 /gene="yyaP" /locus_tag="BSU_40760" /old_locus_tag="BSU40760" CDS complement(4053279..4054655) /gene="tetB" /locus_tag="BSU_40770" /old_locus_tag="BSU40770" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:7961647, 14636065, 15849754, 16850406, 17015648, 25954268" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7961647, 14636065, 15849754, 16850406, 17015648, 25954268; Product type t : transporter" /codon_start=1 /transl_table=11 /product="multifunctional tetracycline-metal/H+ antiporterand Na+(K+)/H+ antiporter" /protein_id="NP_391957.1" /db_xref="EnsemblGenomes-Gn:BSU40770" /db_xref="EnsemblGenomes-Tr:CAB16114" /db_xref="GOA:P23054" /db_xref="InterPro:IPR011701" /db_xref="InterPro:IPR020846" /db_xref="InterPro:IPR036259" /db_xref="SubtiList:BG10036" /db_xref="UniProtKB/Swiss-Prot:P23054" /translation="MNTSYSQSTLRHNQVLIWLCVLSFFSVLNEMVLNVSLPDIANEF NKLPASANWVNTAFMLTFSIGTALYGKLSDQLGIKNLLLFGIMVNGLGSIIGFVGHSF FPILILARFIQGIGAAAFPALVMVVVARYIPKENRGKAFGLIGSLVAMGEGVGPAIGG MVAHYIHWSYLLLIPTATIITVPFLIKLLKKEERIRGHIDMAGIILMSAGIVFFMLFT TSYRFSFLIISILAFFIFVQHIRKAQDPFVDPELGKNVFFVIGTLCGGLIFGTVAGFV SMVPYMMKDVHHLSTAAIGSGIIFPGTMSVIIFGYIGGLLVDRKGSLYVLTIGSALLS SGFLIAAFFIDAAPWIMTIIVIFVFGGLSFTKTVISTVVSSSLKEKEAGAGMSLLNFT SFLSEGTGIAIVGGLLSIGFLDHRLLPIDVDHSTYLYSNMLILFAGIIVICWLVILNV YKRSRRHG*" gene complement(4053279..4054655) /gene="tetB" /locus_tag="BSU_40770" /old_locus_tag="BSU40770" CDS complement(4054689..4054751) /gene="tetL" /locus_tag="BSU_40780" /old_locus_tag="BSU40780" /function="16.3: Control" /function="16.1: Circulate" /experiment="publication(s) with functional evidences, PMID:14636065, 17015648" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 14636065, 17015648; Product type t: transporter" /codon_start=1 /transl_table=11 /product="tetracycline resistance leader peptide" /protein_id="NP_391958.1" /db_xref="EnsemblGenomes-Gn:BSU40780" /db_xref="EnsemblGenomes-Tr:CAB16115" /db_xref="GOA:P23053" /db_xref="InterPro:IPR012618" /db_xref="SubtiList:BG11051" /db_xref="UniProtKB/Swiss-Prot:P23053" /translation="MKCNKMNRVQLKEGSVSMTL*" gene complement(4054689..4054751) /gene="tetL" /locus_tag="BSU_40780" /old_locus_tag="BSU40780" promotor_-10 complement(4054772..4054791) /Source="Nicolas_upshift_promotors" /id="U3216" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.635364635364635" /psig="0.998001998001998" /xcortree=2216 /SigmaFactorBS="ttgtttcgcaatctggtcaaatttttataaaaaaagtaaaAG TTTAATccttagtctataTATAATAAGATCATATCAATcaaatgtagggggagttatt a" /listShort="tetL, tetB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(4054791) /Source="Nicolas_upshifts" /id="U3216" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.635364635364635" /psig="0.998001998001998" /xcortree=2216 /SigmaFactorBS="ttgtttcgcaatctggtcaaatttttataaaaaaagtaaaAG TTTAATccttagtctataTATAATAAGATCATATCAATcaaatgtagggggagttatt a" /listShort="tetL, tetB" /GFF_Attribute="listLong" promotor_-35 complement(4054804..4054811) /Source="Nicolas_upshift_promotors" /id="U3216" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.635364635364635" /psig="0.998001998001998" /xcortree=2216 /SigmaFactorBS="ttgtttcgcaatctggtcaaatttttataaaaaaagtaaaAG TTTAATccttagtctataTATAATAAGATCATATCAATcaaatgtagggggagttatt a" /listShort="tetL, tetB" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 4054939..4054945 /Source="Nicolas_upshift_promotors" /id="U3217" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.612387612387612" /psig="0.998001998001998" /xcortree=618 /SigmaFactorBS="tttcacatcacaattatcgataagcagtcagtTATTGTAttt gtttaggataacTGTGGTAACCTGAATATAACcaacttaggaagaaggtgatcccatg c" /listShort="yyaO" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 4054961..4054980 /Source="Nicolas_upshift_promotors" /id="U3217" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.612387612387612" /psig="0.998001998001998" /xcortree=618 /SigmaFactorBS="tttcacatcacaattatcgataagcagtcagtTATTGTAttt gtttaggataacTGTGGTAACCTGAATATAACcaacttaggaagaaggtgatcccatg c" /listShort="yyaO" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 4054967 /Source="Nicolas_upshifts" /id="U3217" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.612387612387612" /psig="0.998001998001998" /xcortree=618 /SigmaFactorBS="tttcacatcacaattatcgataagcagtcagtTATTGTAttt gtttaggataacTGTGGTAACCTGAATATAACcaacttaggaagaaggtgatcccatg c" /listShort="yyaO" /GFF_Attribute="listLong" CDS 4055004..4055243 /gene="yyaO" /locus_tag="BSU_40790" /old_locus_tag="BSU40790" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_391959.1" /db_xref="EnsemblGenomes-Gn:BSU40790" /db_xref="EnsemblGenomes-Tr:CAB16116" /db_xref="InterPro:IPR004879" /db_xref="InterPro:IPR036249" /db_xref="SubtiList:BG10037" /db_xref="UniProtKB/Swiss-Prot:P37509" /translation="MPNKSKPNRLIAEKSPYLLQHAHNPVDWFPWGEEAFAKAKRENK PVLVSIGYSTTCHWWPGIIKSCGTPLKDNRSHFKR*" gene 4055004..4055243 /gene="yyaO" /locus_tag="BSU_40790" /old_locus_tag="BSU40790" downshifts 4055252 /Source="Nicolas_upshifts" /id="D2115" /incds=0 /nref=7 /ntot=103 /MaxReadThrough="1.03879" /MaxDrop="3.89186" /score="10.758481" /energy="-8.2" /TU="NA" /idTUdmin="U3217" /TUdmin=9 /isTUend="TRUE" promotor_-35 4055336..4055343 /Source="Nicolas_upshift_promotors" /id="U3218" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.952047952047952" /psig="0.994005994005994" /xcortree=1993 /SigmaFactorBS="gcggtagcaggtttttttattTGCTTGACttagagttaactc taAATTGTAAACTAACTTTAATtaaatgagagggatgatgttgttgtattccattagt a" /listShort="yyaN" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 4055359..4055378 /Source="Nicolas_upshift_promotors" /id="U3218" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.952047952047952" /psig="0.994005994005994" /xcortree=1993 /SigmaFactorBS="gcggtagcaggtttttttattTGCTTGACttagagttaactc taAATTGTAAACTAACTTTAATtaaatgagagggatgatgttgttgtattccattagt a" /listShort="yyaN" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 4055375 /Source="Nicolas_upshifts" /id="U3218" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.952047952047952" /psig="0.994005994005994" /xcortree=1993 /SigmaFactorBS="gcggtagcaggtttttttattTGCTTGACttagagttaactc taAATTGTAAACTAACTTTAATtaaatgagagggatgatgttgttgtattccattagt a" /listShort="yyaN" /GFF_Attribute="listLong" CDS 4055394..4055810 /gene="yyaN" /locus_tag="BSU_40800" /old_locus_tag="BSU40800" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 11948146, 14663075; Product type r: regulator" /codon_start=1 /transl_table=11 /product="putative transcriptional regulator (MerR family)" /protein_id="NP_391960.1" /db_xref="EnsemblGenomes-Gn:BSU40800" /db_xref="EnsemblGenomes-Tr:CAB16117" /db_xref="GOA:P37510" /db_xref="InterPro:IPR000551" /db_xref="InterPro:IPR009061" /db_xref="SubtiList:BG10038" /db_xref="UniProtKB/Swiss-Prot:P37510" /translation="MLLYSISKAAEKTSISSYTLRYYEKIGLLPPPKRKNSGRRFYTE TDIQFMLFLKSLKETGMSLEDINEFVKDGCILEKINSDVKSAQLSPSINKRIEILTKH LEKMEIKKRELEEVISTTKGKLDTYYSILKEEVENK*" gene 4055394..4055810 /gene="yyaN" /locus_tag="BSU_40800" /old_locus_tag="BSU40800" CDS 4055807..4056724 /gene="yyaM" /locus_tag="BSU_40810" /old_locus_tag="BSU40810" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative efflux transporter" /protein_id="NP_391961.1" /db_xref="EnsemblGenomes-Gn:BSU40810" /db_xref="EnsemblGenomes-Tr:CAB16118" /db_xref="GOA:P37511" /db_xref="InterPro:IPR000620" /db_xref="SubtiList:BG10039" /db_xref="UniProtKB/Swiss-Prot:P37511" /translation="MKHLNIYIMLLGFSIFTGATFNLAKYTVGYFSPSSSAAWRFGLA AAVMLIILIFTEGIKKSQLRKNAVSYIVLGIIGIFGFNALFFVGLKYTSPVNGALIMG LNPLLTAILARIILKDNMTKKQVLGIFFAFIGVLLVITQGSIETIKTLSISGGDLIIF TGNVCWALYGVLGRRFVKDGTPLSTTTYTMVIGAVSLIVVSLFTSKPVSLSNIPIGVW GAIAFMAFFTSVLGYLWWNQGIKEIGASKTSLFFNLVPVVTMIISFAVGTPIKVFQVI GAVLVILGVLTASGVIRIPKYNTKEQSAI*" gene 4055807..4056724 /gene="yyaM" /locus_tag="BSU_40810" /old_locus_tag="BSU40810" misc_feature 4056751..4056770 /Source="Nicolas_upshift_promotors" /id="U3219" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.841158841158841" /psig="0.984015984015984" /xcortree=1462 /SigmaFactorBS="actaaagaacagtcagctatataaagaaatagggagtatttt tgagaaaaTGTGTTAAGTTAAATATACActaattataggaagaaggtgatcccatgcc a" /listShort="yyaL" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts 4056761 /Source="Nicolas_upshifts" /id="U3219" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.841158841158841" /psig="0.984015984015984" /xcortree=1462 /SigmaFactorBS="actaaagaacagtcagctatataaagaaatagggagtatttt tgagaaaaTGTGTTAAGTTAAATATACActaattataggaagaaggtgatcccatgcc a" /listShort="yyaL" /GFF_Attribute="listLong" promotor_-10 complement(4056765..4056784) /Source="Nicolas_upshift_promotors" /id="U3220" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.616383616383616" /psig="0.978021978021978" /xcortree=3109 /SigmaFactorBS="attgattaatctattgggtttactttTGTTTGGCatgggatc accttCTTCCTATAATTAGTGTATAtttaacttaacacattttctcaaaaatactccc t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(4056771) /Source="Nicolas_upshifts" /id="U3220" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.616383616383616" /psig="0.978021978021978" /xcortree=3109 /SigmaFactorBS="attgattaatctattgggtttactttTGTTTGGCatgggatc accttCTTCCTATAATTAGTGTATAtttaacttaacacattttctcaaaaatactccc t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" CDS 4056796..4058865 /gene="yyaL" /locus_tag="BSU_40820" /old_locus_tag="BSU40820" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 4: Unknown function but conserved in otherorganisms" /codon_start=1 /transl_table=11 /product="conserved hypothetical protein" /protein_id="NP_391962.1" /db_xref="EnsemblGenomes-Gn:BSU40820" /db_xref="EnsemblGenomes-Tr:CAB16119" /db_xref="GOA:P37512" /db_xref="InterPro:IPR004879" /db_xref="InterPro:IPR008928" /db_xref="InterPro:IPR024705" /db_xref="InterPro:IPR036249" /db_xref="SubtiList:BG10040" /db_xref="UniProtKB/Swiss-Prot:P37512" /translation="MPNKSKPNRLINEKSPYLLQHAHNPVDWFPWGEEAFEKAKRENK PVLVSIGYSTCHWCHVMAHESFEDEEIARLLNERFVAIKVDREERPDVDSVYMRICQL MTGQGGWPLNVFITPDQKPFYAGTYFPKTSKFNRPGFVDVLEHLSETFANDREHVEDI AENAAKHLQTKTAAKTGEGLSESAIHRTFQQLASGFDTIYGGFGQAPKFPMPHMLMYL LRYDHNTGQENALYNVTKTLDSMANGGIYDHIGYGFARYSTDDEWLVPHFEKMLYDNA LLLTAYTEAYQVTQNSRYKEICEQIITFIQREMTHEDGSFFSALDADTEGEEGKYYVW SKEEILKTLGDDLGTLYCQVYDITEEGNFEGKNIPNLIHTKREQIKEDAGLTEKELSL KLEDARQQLLKTREERTYPHVDDKVLTSWNALMIAGLAKAAKVYQEPKYLSLAKDAIT FIENKLIIDGRVMVRYRDGEVKNKGFIDDYAFLLWAYLDLYEASFDLSYLQKAKKLTD DMISLFWDEEHGGFYFTGHDAEALIVREKEVYDGAVPSGNSVAAVQLLRLGQVTGDLS LIEKAETMFSVFKPDIEAYPSGHAFFMQSVLRHLMPKKEIVIFGSADDPARKQIIAEL QKAFKPNDSILVAEQPEQCKDIAPFAADYRIIDGKTTVYICENFACQQPTTNIEEAIH TLISSRD*" gene 4056796..4058865 /gene="yyaL" /locus_tag="BSU_40820" /old_locus_tag="BSU40820" promotor_-35 complement(4056798..4056805) /Source="Nicolas_upshift_promotors" /id="U3220" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.616383616383616" /psig="0.978021978021978" /xcortree=3109 /SigmaFactorBS="attgattaatctattgggtttactttTGTTTGGCatgggatc accttCTTCCTATAATTAGTGTATAtttaacttaacacattttctcaaaaatactccc t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 4058829 /Source="Nicolas_upshifts" /id="D2116" /incds=0 /nref=221 /ntot=260 /MaxReadThrough="1.24617" /MaxDrop="5.71843" /score="11.6894527" /energy="-16.6" /TU="NA" /idTUdmin="U3219" /TUdmin=0 /isTUend="TRUE" CDS complement(4058862..4059761) /gene="yyaK" /locus_tag="BSU_40830" /old_locus_tag="BSU40830" /function="16.6: Maintain" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 11343912, 15849754, 16850406; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative integral inner membrane protease" /protein_id="NP_391963.1" /db_xref="EnsemblGenomes-Gn:BSU40830" /db_xref="EnsemblGenomes-Tr:CAB16120" /db_xref="GOA:P37513" /db_xref="InterPro:IPR003675" /db_xref="SubtiList:BG10041" /db_xref="UniProtKB/Swiss-Prot:P37513" /translation="MNSFIRPIEGNNTLWRYFFAFLVMVGLYVLGNIAYLFAILFTVI VNPNITFDLDEAVLSDPLVDLYLSHVIYLFAIPGVWLAVRFILKRPFRTVITPNSKMN WRRISFGFIAYFLLMIAVQLIDFVIHPDSYSMQEFNASRFIWLLAAALILVPIQTSAE ELFFRGFLLQAFGRLTKNPLFLTLIVGGLFGVLHFANPEMNNGAVWAGIEYLTFGFVW TYYTIKTGSIEISLGAHAANNMFLCMFITEKNSVYGGIPSLFTVTRGNPMWEAFFTIA VNLVFAGIALWYHKKSKSKQQGS*" gene complement(4058862..4059761) /gene="yyaK" /locus_tag="BSU_40830" /old_locus_tag="BSU40830" downshifts complement(4058905) /Source="Nicolas_upshifts" /id="D2117" /incds=0 /nref=65 /ntot=246 /MaxReadThrough="2.6155" /MaxDrop="3.91098" /score="23.2445146" /energy="-14.7" /TU="NA" /idTUdmin="U3221" /TUdmin=0 /isTUend="TRUE" promotor_-10 complement(4059790..4059809) /Source="Nicolas_upshift_promotors" /id="U3221" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.839160839160839" /psig="0.98001998001998" /xcortree=2400 /SigmaFactorBS="ttatattttaattttgcttaaaagatttccaaaacAGTAGAT TcatagaccaatttaTGCAAATATATAGTAATATTctcattgaaaggaagagacatag a" /listShort="yyaK" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(4059806) /Source="Nicolas_upshifts" /id="U3221" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.839160839160839" /psig="0.98001998001998" /xcortree=2400 /SigmaFactorBS="ttatattttaattttgcttaaaagatttccaaaacAGTAGAT TcatagaccaatttaTGCAAATATATAGTAATATTctcattgaaaggaagagacatag a" /listShort="yyaK" /GFF_Attribute="listLong" S_feature complement(4059808..4061039) /Source="Nicolas_S_feature" /locus_tag="new_4194210_4195441_c" /HighExp="S6, S8, S7, S5, B36, BT, S4, B60, S3, Diami" /AntisenseName="yyaJ" /AntisenseCor="-0.24400480530035801" /AntisenseRegPval="-4.3" /CDS_PredictionProba="NA" /TUshortSig="SigK" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1573" promotor_-35 complement(4059824..4059831) /Source="Nicolas_upshift_promotors" /id="U3221" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.839160839160839" /psig="0.98001998001998" /xcortree=2400 /SigmaFactorBS="ttatattttaattttgcttaaaagatttccaaaacAGTAGAT TcatagaccaatttaTGCAAATATATAGTAATATTctcattgaaaggaagagacatag a" /listShort="yyaK" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-35 4059902..4059909 /Source="Nicolas_upshift_promotors" /id="U3222" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.725274725274725" /psig="0.978021978021978" /xcortree=3158 /SigmaFactorBS="tgtgaatttagttcttccatctagtgatttgaaCTCTGTTGc caatgaaccaagATACTTATAATAGTCCCAAGaggggaattttcagtcttttctacta c" /listShort="yyaJ" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 4059923..4059942 /Source="Nicolas_upshift_promotors" /id="U3222" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.725274725274725" /psig="0.978021978021978" /xcortree=3158 /SigmaFactorBS="tgtgaatttagttcttccatctagtgatttgaaCTCTGTTGc caatgaaccaagATACTTATAATAGTCCCAAGaggggaattttcagtcttttctacta c" /listShort="yyaJ" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 4059929 /Source="Nicolas_upshifts" /id="U3222" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.725274725274725" /psig="0.978021978021978" /xcortree=3158 /SigmaFactorBS="tgtgaatttagttcttccatctagtgatttgaaCTCTGTTGc caatgaaccaagATACTTATAATAGTCCCAAGaggggaattttcagtcttttctacta c" /listShort="yyaJ" /GFF_Attribute="listLong" CDS 4059987..4061342 /gene="yyaJ" /locus_tag="BSU_40840" /old_locus_tag="BSU40840" /function="16.1: Circulate" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406, 9529885, 19087206, 22720735; Product type t : transporter" /codon_start=1 /transl_table=11 /product="putative transporter" /protein_id="NP_391964.2" /db_xref="EnsemblGenomes-Gn:BSU40840" /db_xref="EnsemblGenomes-Tr:CAB16121" /db_xref="GOA:P37514" /db_xref="InterPro:IPR005828" /db_xref="InterPro:IPR020846" /db_xref="InterPro:IPR036259" /db_xref="SubtiList:BG10042" /db_xref="UniProtKB/Swiss-Prot:P37514" /translation="MNTIFKQKNTHPFSNAANRLDRLPISRVHFQVLTALGIVYFFDL ADLFTLSNVAPALIEHWGIPLSTIANVTAASFLGMFLGASLGGRLSDRIGRKKALNLF VFVFSIASLCNAAAWDIPSLMTFRFLTGFGVAAAMVITNSYLAEFFPSSVRGKYISFC AMIGLIGVPITNIVSAFVIPLGSWGWRLVFVWGAVGLIYFFFIHRLEESPRWHENRGE YAKADAILTRIEEQVEKEKGPLPAASQPKVSETVKQNAGYAGLLKGRNLKITIVLSAV WIFETFGFYGFASWVPSLLKSNGVTMENTLWYNVLHSVGAPLGALLGSMISERFQRKW ILAASAFLTAIAGLLYGMTFIPIMIIVFGFIVNITERVFTSNLYAYTSEPYPTEYRSS GSGLAYGLGRFSNIFGSLLVGFIAVQLGYISVFLFIGGCWLACSLLLIFFGPNTNAKQ I*" gene 4059987..4061342 /gene="yyaJ" /locus_tag="BSU_40840" /old_locus_tag="BSU40840" promotor_-10 complement(4061025..4061044) /Source="Nicolas_upshift_promotors" /id="U3223" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1260 /SigmaFactorBS="aggtaaagacccgttctgtgatattcacgataaaaccaaata CAATGATCATgatgggaataaaaGTCATACCATATAAGAGCCCggcgatggccgtcag a" /listShort="S1573, yyaK" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(4061049) /Source="Nicolas_upshifts" /id="U3223" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1260 /SigmaFactorBS="aggtaaagacccgttctgtgatattcacgataaaaccaaata CAATGATCATgatgggaataaaaGTCATACCATATAAGAGCCCggcgatggccgtcag a" /listShort="S1573, yyaK" /GFF_Attribute="listLong" promotor_-35 complement(4061058..4061067) /Source="Nicolas_upshift_promotors" /id="U3223" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp=1 /psig=1 /xcortree=1260 /SigmaFactorBS="aggtaaagacccgttctgtgatattcacgataaaaccaaata CAATGATCATgatgggaataaaaGTCATACCATATAAGAGCCCggcgatggccgtcag a" /listShort="S1573, yyaK" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(4061376..4061930) /gene="maa" /locus_tag="BSU_40850" /old_locus_tag="BSU40850" /EC_number="2.3.1.79" /function="16.8: Protect" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 12731863, 12793527, 19087206, 22226636, 22720735; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="maltose O-acetyltransferase" /protein_id="NP_391965.1" /db_xref="EnsemblGenomes-Gn:BSU40850" /db_xref="EnsemblGenomes-Tr:CAB16122" /db_xref="GOA:P37515" /db_xref="InterPro:IPR001451" /db_xref="InterPro:IPR011004" /db_xref="InterPro:IPR018357" /db_xref="InterPro:IPR024688" /db_xref="SubtiList:BG10043" /db_xref="UniProtKB/Swiss-Prot:P37515" /translation="MLRTEKEKMAAGELYNSEDQQLLLERKHARQLIRQYNETPEDDA VRTKLLKELLGSVGDQVTILPTFRCDYGYHIHIGDHTFVNFDCVILDVCEVRIGCHCL IAPGVHIYTAGHPLDPIERKSGKEFGKPVTIGDQVWIGGRAVINPGVTIGDNAVIASG SVVTKDVPANTVVGGNPARILKQL*" gene complement(4061376..4061930) /gene="maa" /locus_tag="BSU_40850" /old_locus_tag="BSU40850" CDS complement(4061948..4062328) /gene="yyaH" /locus_tag="BSU_40860" /old_locus_tag="BSU40860" /function="16.11: Scavenge (Catabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 19087206; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative C-S lyase" /protein_id="NP_391966.1" /db_xref="EnsemblGenomes-Gn:BSU40860" /db_xref="EnsemblGenomes-Tr:CAB16123" /db_xref="InterPro:IPR004360" /db_xref="InterPro:IPR029068" /db_xref="SubtiList:BG10044" /db_xref="UniProtKB/Swiss-Prot:P37516" /translation="MQIEHTAVWVNDLERMKSFYESYFNGEANDLYHNEKKDFKSYFI TFDSGARLEIMKKGNVTDPPSQTMTGWAHIAFSVGSREKVDELTDRLKADGFAVVNGP RTTGDGYYESVIEDDEGNLIEITI*" gene complement(4061948..4062328) /gene="yyaH" /locus_tag="BSU_40860" /old_locus_tag="BSU40860" CDS complement(4062384..4063319) /gene="ccpB" /locus_tag="BSU_40870" /old_locus_tag="BSU40870" /function="16.3: Control" /experiment="publication(s) with functional evidences, PMID:9457849, 9642180, 16267306" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9457849, 9642180, 16267306; Product type r: regulator" /codon_start=1 /transl_table=11 /product="transcriptional repressor of carbon supply (LacIfamily)" /protein_id="NP_391967.1" /db_xref="EnsemblGenomes-Gn:BSU40870" /db_xref="EnsemblGenomes-Tr:CAB16124" /db_xref="GOA:P37517" /db_xref="InterPro:IPR000843" /db_xref="InterPro:IPR001761" /db_xref="InterPro:IPR010982" /db_xref="InterPro:IPR028082" /db_xref="SubtiList:BG10045" /db_xref="UniProtKB/Swiss-Prot:P37517" /translation="MANIKEIARLANVSVSTVSRVLNHHPYVSEEKRKLVHQVMKELD YTPNRTAIDLIRGKTHTVGVILPYSDHPCFDKIVNGITKAAFQHEYATTLLPTNYNPD IEIKYLELLRTKKIDGLIITSRANHWDSILAYQEYGPVIACEDTGDIDVPCAFNDRKT AYAESFRYLKSRGHENIAFTCVREADRSPSTADKAAAYKAVCGRLEDRHMLSGCNDMN DGELAAEHFYMSGRVPTAIYANSDEVAAGIHLFAKKNNWDVEIIGEGNTSISRVLGFP SLDLNLEQLGIAAFSLFLQDEPADIKIQHKFKKKA*" gene complement(4062384..4063319) /gene="ccpB" /locus_tag="BSU_40870" /old_locus_tag="BSU40870" promotor_-35 4063309..4063318 /Source="Nicolas_upshift_promotors" /id="U3224" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.967032967032967" /psig="0.967032967032967" /xcortree=1390 /SigmaFactorBS="gatacatttgccagtcttgcgatctcttttATATTTGCCAtc tctttctccttTTCATATAAAAAAAGCAGTAagtgtaaaatccttactgctatctcat c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 4063332..4063351 /Source="Nicolas_upshift_promotors" /id="U3224" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.967032967032967" /psig="0.967032967032967" /xcortree=1390 /SigmaFactorBS="gatacatttgccagtcttgcgatctcttttATATTTGCCAtc tctttctccttTTCATATAAAAAAAGCAGTAagtgtaaaatccttactgctatctcat c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 4063339 /Source="Nicolas_upshifts" /id="U3224" /multdbtbs="-" /comp="M5" /sig="SigK" /pcomp="0.967032967032967" /psig="0.967032967032967" /xcortree=1390 /SigmaFactorBS="gatacatttgccagtcttgcgatctcttttATATTTGCCAtc tctttctccttTTCATATAAAAAAAGCAGTAagtgtaaaatccttactgctatctcat c" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-10 complement(4063363..4063382) /Source="Nicolas_upshift_promotors" /id="U3225" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.5004995004995" /psig="0.998001998001998" /xcortree=2935 /SigmaFactorBS="atatcagcggacgtcatgggttccgaccattgtccTGTTGAA CttatcatcaataTATGATGAGATAGCAGTAAGgattttacacttactgcttttttta t" /listShort="ccpB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(4063377) /Source="Nicolas_upshifts" /id="U3225" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.5004995004995" /psig="0.998001998001998" /xcortree=2935 /SigmaFactorBS="atatcagcggacgtcatgggttccgaccattgtccTGTTGAA CttatcatcaataTATGATGAGATAGCAGTAAGgattttacacttactgcttttttta t" /listShort="ccpB" /GFF_Attribute="listLong" CDS complement(4063378..4064136) /gene="exoA" /locus_tag="BSU_40880" /old_locus_tag="BSU40880" /EC_number="3.1.11.2" /function="16.6: Maintain" /function="16.8: Protect" /experiment="publication(s) with functional evidences, PMID:10540738, 16237020, 18203828, 21441501, 24244006, 24914186" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10540738, 16237020, 18203828, 21441501, 24244006, 24914186; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="apurinic/apyrimidinic endonuclease" /protein_id="NP_391968.1" /db_xref="EnsemblGenomes-Gn:BSU40880" /db_xref="EnsemblGenomes-Tr:CAB16125" /db_xref="GOA:P37454" /db_xref="InterPro:IPR004808" /db_xref="InterPro:IPR005135" /db_xref="InterPro:IPR020847" /db_xref="InterPro:IPR020848" /db_xref="InterPro:IPR036691" /db_xref="PDB:5CFE" /db_xref="SubtiList:BG10046" /db_xref="UniProtKB/Swiss-Prot:P37454" /translation="MKLISWNVNGLRAVMRKMDFLSYLKEEDADIICLQETKIQDGQV DLQPEDYHVYWNYAVKKGYSGTAVFSKQEPLQVIYGIGVEEHDQEGRVITLEFENVFV MTVYTPNSRRGLERIDYRMQWEEALLSYILELDQKKPVILCGDLNVAHQEIDLKNPKA NRNNAGFSDQEREAFTRFLEAGFVDSFRHVYPDLEGAYSWWSYRAGARDRNIGWRIDY FVVSESLKEQIEDASISADVMGSDHCPVELIINI*" gene complement(4063378..4064136) /gene="exoA" /locus_tag="BSU_40880" /old_locus_tag="BSU40880" promotor_-35 complement(4063395..4063402) /Source="Nicolas_upshift_promotors" /id="U3225" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.5004995004995" /psig="0.998001998001998" /xcortree=2935 /SigmaFactorBS="atatcagcggacgtcatgggttccgaccattgtccTGTTGAA CttatcatcaataTATGATGAGATAGCAGTAAGgattttacacttactgcttttttta t" /listShort="ccpB" /GFF_Attribute="listLong" /label="promotor_-35" S_feature 4063669..4064172 /Source="Nicolas_S_feature" /locus_tag="new_4198071_4198574" /HighExp="C30, S8, S7, S6, BT, S5, M/G, Glucon, C90, T1.0H" /AntisenseName="exoAA" /AntisenseCor="-0.177921457862244" /AntisenseRegPval="-2.5" /CDS_PredictionProba="NA" /TUshortSig="NA" /TUshortPSig="NA" /TUlongSig="NA" /TUlongPSig="NA" /label="S1574" downshifts 4064131 /Source="Nicolas_upshifts" /id="D2118" /incds=0 /nref=2 /ntot=12 /MaxReadThrough="2.65789" /MaxDrop="4.11352" /score="16.4680636" /energy="-6.8" /TU="NA" /idTUdmin="U3224" /TUdmin=528 /isTUend="FALSE" CDS complement(4064201..4064440) /gene="rpsR" /locus_tag="BSU_40890" /old_locus_tag="BSU40890" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:12682299, 14762004, 22720735, 24310371" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12682299, 14762004, 22720735, 24310371; Product type s: structure" /codon_start=1 /transl_table=11 /product="ribosomal protein S18" /protein_id="NP_391969.2" /db_xref="EnsemblGenomes-Gn:BSU40890" /db_xref="EnsemblGenomes-Tr:CAB16126" /db_xref="GOA:P21475" /db_xref="InterPro:IPR001648" /db_xref="InterPro:IPR018275" /db_xref="InterPro:IPR036870" /db_xref="PDB:3J9W" /db_xref="PDB:5NJT" /db_xref="SubtiList:BG10047" /db_xref="UniProtKB/Swiss-Prot:P21475" /translation="MAGGRRGGRAKRRKVCYFTSNGITHIDYKDVDLLKKFVSERGKI LPRRVTGTNAKYQRKLTAAIKRARQMALLPYVSGE*" gene complement(4064201..4064440) /gene="rpsR" /locus_tag="BSU_40890" /old_locus_tag="BSU40890" downshifts complement(4064207) /Source="Nicolas_upshifts" /id="D2119" /incds=0 /nref=217 /ntot=268 /MaxReadThrough="4.97781" /MaxDrop="7.46952" /score="21.7622917" /energy="-15.3" /TU="U3226,U3227" /idTUdmin="U3229" /TUdmin=0 /isTUend="TRUE" downshifts complement(4064275) /Source="Nicolas_upshifts" /id="D2120" /incds=1 /nref=13 /ntot=142 /MaxReadThrough="8.89363" /MaxDrop="3.9797" /score="21.7622917" /energy="-15.3" /TU="U3226,U3227,U3229" /idTUdmin="U3229" /TUdmin="-68" /isTUend="FALSE" CDS complement(4064484..4065002) /gene="ssbA" /locus_tag="BSU_40900" /old_locus_tag="BSU40900" /function="16.9: Replicate" /experiment="publication(s) with functional evidences, PMID:12682299, 14762004, 16549871, 10072765, 25138221, 26001966, 28575448" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12682299, 14762004, 16549871, 10072765, 25138221, 26001966, 28575448; Product type f: factor" /codon_start=1 /transl_table=11 /product="single-strand DNA-binding protein" /protein_id="NP_391970.1" /db_xref="EnsemblGenomes-Gn:BSU40900" /db_xref="EnsemblGenomes-Tr:CAB16127" /db_xref="GOA:P37455" /db_xref="InterPro:IPR000424" /db_xref="InterPro:IPR011344" /db_xref="InterPro:IPR012340" /db_xref="SubtiList:BG10048" /db_xref="UniProtKB/Swiss-Prot:P37455" /translation="MLNRVVLVGRLTKDPELRYTPNGAAVATFTLAVNRTFTNQSGER EADFINCVTWRRQAENVANFLKKGSLAGVDGRLQTRNYENQQGQRVFVTEVQAESVQF LEPKNGGGSGSGGYNEGNSGGGQYFGGGQNDNPFGGNQNNQRRNQGNSFNDDPFANDG KPIDISDDDLPF*" gene complement(4064484..4065002) /gene="ssbA" /locus_tag="BSU_40900" /old_locus_tag="BSU40900" CDS complement(4065043..4065330) /gene="rpsF" /locus_tag="BSU_40910" /old_locus_tag="BSU40910" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:12682299, 14762004, 19653700, 26447183" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12682299, 14762004, 19653700, 26447183; Product type s: structure" /codon_start=1 /transl_table=11 /product="ribosomal protein S6 (BS9)" /protein_id="NP_391971.1" /db_xref="EnsemblGenomes-Gn:BSU40910" /db_xref="EnsemblGenomes-Tr:CAB16128" /db_xref="GOA:P21468" /db_xref="InterPro:IPR000529" /db_xref="InterPro:IPR014717" /db_xref="InterPro:IPR020814" /db_xref="InterPro:IPR020815" /db_xref="InterPro:IPR035980" /db_xref="PDB:3J9W" /db_xref="PDB:5NJT" /db_xref="SubtiList:BG10049" /db_xref="UniProtKB/Swiss-Prot:P21468" /translation="MRKYEVMYIIRPNIDEESKKAVIERFNNVLTSNGAEITGTKDWG KRRLAYEINDFRDGFYQIVNVQSDAAAVQEFDRLAKISDDIIRHIVVKEEE*" gene complement(4065043..4065330) /gene="rpsF" /locus_tag="BSU_40910" /old_locus_tag="BSU40910" S_feature complement(4065331..4065397) /Source="Nicolas_S_feature" /locus_tag="new_4199733_4199799_c" /HighExp="MG t5, LPhT, GM 90, SMM, T-5.40H, GM-0.2, MG 150, GM 45, Gly, M9-exp" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA, SigA" /TUshortPSig="1, 0.993, 0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S1575" promotor_-10 complement(4065396..4065415) /Source="Nicolas_upshift_promotors" /id="U3226" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.443556443556444" /psig=1 /xcortree=2653 /SigmaFactorBS="tccgatttaatgtataggatgcaGTTGTAaagggacaagagc TTTGGTATAATATAAAATTGtgagtaatagaattattgctccttgcccattatgggcc g" /listShort="S1575, rpsF, ssbA, rpsR, exoAA, ccpB" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(4065397) /Source="Nicolas_upshifts" /id="U3226" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.443556443556444" /psig=1 /xcortree=2653 /SigmaFactorBS="tccgatttaatgtataggatgcaGTTGTAaagggacaagagc TTTGGTATAATATAAAATTGtgagtaatagaattattgctccttgcccattatgggcc g" /listShort="S1575, rpsF, ssbA, rpsR, exoAA, ccpB" /GFF_Attribute="listLong" promotor_-35 complement(4065429..4065434) /Source="Nicolas_upshift_promotors" /id="U3226" /multdbtbs="-" /comp="M17" /sig="SigA" /pcomp="0.443556443556444" /psig=1 /xcortree=2653 /SigmaFactorBS="tccgatttaatgtataggatgcaGTTGTAaagggacaagagc TTTGGTATAATATAAAATTGtgagtaatagaattattgctccttgcccattatgggcc g" /listShort="S1575, rpsF, ssbA, rpsR, exoAA, ccpB" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(4065441..4066541) /gene="engD" /locus_tag="BSU_40920" /old_locus_tag="BSU40920" /function="16.6: Maintain" /function="16.8: Protect" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 12837776, 16014871, 18713637, 21527254, 22995830, 26018081, 26160547, 26912459; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="potassium-dependent informational ATPase interacting with 70S ribosome; ROS stress regulator" /protein_id="NP_391972.1" /db_xref="EnsemblGenomes-Gn:BSU40920" /db_xref="EnsemblGenomes-Tr:CAB16129" /db_xref="GOA:P37518" /db_xref="InterPro:IPR004396" /db_xref="InterPro:IPR006073" /db_xref="InterPro:IPR012675" /db_xref="InterPro:IPR012676" /db_xref="InterPro:IPR013029" /db_xref="InterPro:IPR023192" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR031167" /db_xref="SubtiList:BG10050" /db_xref="UniProtKB/Swiss-Prot:P37518" /translation="MALTAGIVGLPNVGKSTLFNAITQAGAESANYPFCTIDPNVGIV EVPDDRLQKLTELVNPKKTVPTAFEFTDIAGIVKGASKGEGLGNKFLSHIRQVDAICH VVRAFSDDNITHVSGKVDPIDDIETINLELILADMETVEKRITRVSKLAKQKDKDAVF EFEILSKLKEAFESEKPARSVEFTEEQQKLVKQLHLLTSKPILYVANVSEDEVADPSG NENVAKIREYAAGENAEVIVVCAKIESEIAELEGEEKQMFLEELGIQESGLDQLIKAS YSLLGLATYFTAGEQEVRAWTFKKGMKAPECAGIIHSDFERGFIRAETVAYEDLLAGG GMAGAKEAGKVRLEGKEYVVQDGDVIHFRFNV*" gene complement(4065441..4066541) /gene="engD" /locus_tag="BSU_40920" /old_locus_tag="BSU40920" promotor_-10 complement(4066589..4066608) /Source="Nicolas_upshift_promotors" /id="U3227" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.65034965034965" /psig="0.993006993006993" /xcortree=2193 /SigmaFactorBS="aagggattggcaagctgaaaatgcttttttgtcaGCTTGTCT tttccagtgaacctCCTTATAATTGCTCTAGGTTcaaaatacgttcatacaatgacgg t" /listShort="engD, S1575, rpsF, ssbA, rpsR, exoAA" /listLong="ccpB" /label="promotor_-10" upshifts complement(4066604) /Source="Nicolas_upshifts" /id="U3227" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.65034965034965" /psig="0.993006993006993" /xcortree=2193 /SigmaFactorBS="aagggattggcaagctgaaaatgcttttttgtcaGCTTGTCT tttccagtgaacctCCTTATAATTGCTCTAGGTTcaaaatacgttcatacaatgacgg t" /listShort="engD, S1575, rpsF, ssbA, rpsR, exoAA" /listLong="ccpB" promotor_-35 complement(4066623..4066630) /Source="Nicolas_upshift_promotors" /id="U3227" /multdbtbs="-" /comp="M14" /sig="SigA" /pcomp="0.65034965034965" /psig="0.993006993006993" /xcortree=2193 /SigmaFactorBS="aagggattggcaagctgaaaatgcttttttgtcaGCTTGTCT tttccagtgaacctCCTTATAATTGCTCTAGGTTcaaaatacgttcatacaatgacgg t" /listShort="engD, S1575, rpsF, ssbA, rpsR, exoAA" /listLong="ccpB" /label="promotor_-35" CDS complement(4066668..4068671) /gene="yyaE" /locus_tag="BSU_40930" /old_locus_tag="BSU40930" /EC_number="1.-.-.-" /function="3.2: Degradation" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 17114254, 20817769; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="putative oxidoreductase (molybdoenzyme)" /protein_id="NP_391973.1" /db_xref="EnsemblGenomes-Gn:BSU40930" /db_xref="EnsemblGenomes-Tr:CAB16130" /db_xref="GOA:P37519" /db_xref="InterPro:IPR006656" /db_xref="InterPro:IPR006657" /db_xref="InterPro:IPR006963" /db_xref="InterPro:IPR009010" /db_xref="SubtiList:BG10051" /db_xref="UniProtKB/Swiss-Prot:P37519" /translation="MSKVHQSACPLNCWDSCGFLVTVDDGKVTKVDGDPNHPITEGKI CGRGRMLETKTNSPDRLRYPMKKQNGEFVRISWEQALDEIADKLREIKETSETTAVLH SHDYANNGLLKALDQRFFNGYGGVTEIVGSICWGSGIEAQSWDFGRSYGHGPLDIYNS KHVVVWGRNVSRTNMHLYHHLQQVKKKGATITVIDPIFNPTAKLADRYISVKPGMDGW LAAAVLKVLIEMGRTDETFISEHSVGFDDVKELLKTVSLEEFIVKTETSMEELEYLAG LYADGPVSTFMGLGMQRYKNGGGTIRWIDALVAASGNVGIKGGGANFGNVQIGESFAK TKLTLPELKTTSRSFSMMTQAEEVLTAADPAIEMIIVTCGNPLTQVPNTNKVRQAFEK VPMTVAIDSIMTDTAELCDYVLPTATVFEEEDIYYSSMYHHYVQYGKKLVEPQGEAKS DSWIWSELAKRLGFGELFEYSTQEFLEMGLSSLEAEDVTLERLKEKGHLPLPVKQVPW DDYQFLTPSGKFEFTSSLAEQKGFSGSLQLNVPEESVFHNEELAGKYPYTLLSIHPQR SNHSQHVPFIEKLQHVQVDISPDIAAGQDLQDGDEVVIFNDRGSMKGKVKVMKQAHAK TINIDEGMWAAFGGSVNALTNDTNSDNGMGSTLFDCLVGLKKA*" gene complement(4066668..4068671) /gene="yyaE" /locus_tag="BSU_40930" /old_locus_tag="BSU40930" CDS complement(4068722..4068928) /gene="yyzM" /locus_tag="BSU_40939" /old_locus_tag="BSU40939" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 21348639, 22333191, 27435445; Product type f: factor" /codon_start=1 /transl_table=11 /product="putative nucleic acid binding protein" /protein_id="YP_003097803.1" /db_xref="EnsemblGenomes-Gn:BSU40939" /db_xref="EnsemblGenomes-Tr:CAX52723" /db_xref="InterPro:IPR009296" /db_xref="UniProtKB/Swiss-Prot:C0H3V8" /translation="MADKDFGLNDIVEMKKPHPCGANSWKIIRMGMDIRIKCEGCSHS VMIPRREFERKLKKVLVKHEEPTS*" gene complement(4068722..4068928) /gene="yyzM" /locus_tag="BSU_40939" /old_locus_tag="BSU40939" promotor_-10 complement(4068890..4068909) /Source="Nicolas_upshift_promotors" /id="U3228" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.655344655344655" /psig="0.83016983016983" /xcortree=1588 /SigmaFactorBS="ttttttgtacaatagatacagcagtttaggaaaagaggtgaa gggTCTTGGCggataaagactttgGCCTGAATGATATCGTAGAAatgaaaaaaccgca t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(4068915) /Source="Nicolas_upshifts" /id="U3228" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.655344655344655" /psig="0.83016983016983" /xcortree=1588 /SigmaFactorBS="ttttttgtacaatagatacagcagtttaggaaaagaggtgaa gggTCTTGGCggataaagactttgGCCTGAATGATATCGTAGAAatgaaaaaaccgca t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" promotor_-35 complement(4068924..4068930) /Source="Nicolas_upshift_promotors" /id="U3228" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.655344655344655" /psig="0.83016983016983" /xcortree=1588 /SigmaFactorBS="ttttttgtacaatagatacagcagtttaggaaaagaggtgaa gggTCTTGGCggataaagactttgGCCTGAATGATATCGTAGAAatgaaaaaaccgca t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(4068954..4068973) /Source="Nicolas_upshift_promotors" /id="U3229" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.646353646353646" /psig="0.999000999001" /xcortree=1832 /SigmaFactorBS="ataagaggatgtatttcttttcgggtatcttGATTGctctta tgatcagtttTTTTGTACAATAGATACAGCagtttaggaaaagaggtgaagggtcttg g" /listShort="yyzM, yyaE, engD, S1575, rpsF, ssbA, rpsR" /listLong="exoAA" /label="promotor_-10" upshifts complement(4068965) /Source="Nicolas_upshifts" /id="U3229" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.646353646353646" /psig="0.999000999001" /xcortree=1832 /SigmaFactorBS="ataagaggatgtatttcttttcgggtatcttGATTGctctta tgatcagtttTTTTGTACAATAGATACAGCagtttaggaaaagaggtgaagggtcttg g" /listShort="yyzM, yyaE, engD, S1575, rpsF, ssbA, rpsR" /listLong="exoAA" promotor_-35 complement(4068990..4068994) /Source="Nicolas_upshift_promotors" /id="U3229" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.646353646353646" /psig="0.999000999001" /xcortree=1832 /SigmaFactorBS="ataagaggatgtatttcttttcgggtatcttGATTGctctta tgatcagtttTTTTGTACAATAGATACAGCagtttaggaaaagaggtgaagggtcttg g" /listShort="yyzM, yyaE, engD, S1575, rpsF, ssbA, rpsR" /listLong="exoAA" /label="promotor_-35" CDS complement(4069022..4070038) /gene="yyaD" /locus_tag="BSU_40940" /old_locus_tag="BSU40940" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16847258, 16850406; Product type t: transporter" /codon_start=1 /transl_table=11 /product="putative transporter" /protein_id="NP_391974.1" /db_xref="EnsemblGenomes-Gn:BSU40940" /db_xref="EnsemblGenomes-Tr:CAB16131" /db_xref="SubtiList:BG10052" /db_xref="UniProtKB/Swiss-Prot:P37520" /translation="MLWRAGMKWMLLILGSLIGAGYASGQEIWQFFGAESGLAIVLFT IMFIFSSYIVMKISFKVQSTHFLPVLEHLMGPWLAKIYDVLIIFYLFSTTMVMIAGGG VTLQMYKLPFWWGITLICIVTVCLFLWDVKGILSINSILIPVLVAGLLYALISFQSTH HHTWTIDLSQQYNWPASITFTSLNILSVVAILSSVGKEMKGLGEAKIASVASGLIFGV ISFVYNETLVELAGSLSQFEIPLFAVLEGAPYFLFLCMTAVLCLAIYTTTVAGLLGLS SRLMAFIHMPRWMIVLILLVLMVPFTSFGFSDLIAFLYPIYGMLNLYLLVCLLLYPIL SKWK*" gene complement(4069022..4070038) /gene="yyaD" /locus_tag="BSU_40940" /old_locus_tag="BSU40940" promotor_-10 complement(4070071..4070089) /Source="Nicolas_upshift_promotors" /id="U3230" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp="0.996003996003996" /psig="0.996003996003996" /xcortree=972 /SigmaFactorBS="tttcagcttgtgttcaaatgtctatgaaaatatGGCATGttt gctttcctttatTTATATAGTAACAATAACGggaacaagctgaactttgtctatgagg t" /listShort="yyaD" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(4070083) /Source="Nicolas_upshifts" /id="U3230" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp="0.996003996003996" /psig="0.996003996003996" /xcortree=972 /SigmaFactorBS="tttcagcttgtgttcaaatgtctatgaaaatatGGCATGttt gctttcctttatTTATATAGTAACAATAACGggaacaagctgaactttgtctatgagg t" /listShort="yyaD" /GFF_Attribute="listLong" promotor_-35 complement(4070105..4070110) /Source="Nicolas_upshift_promotors" /id="U3230" /multdbtbs="SigE" /comp="M3" /sig="SigEF" /pcomp="0.996003996003996" /psig="0.996003996003996" /xcortree=972 /SigmaFactorBS="tttcagcttgtgttcaaatgtctatgaaaatatGGCATGttt gctttcctttatTTATATAGTAACAATAACGggaacaagctgaactttgtctatgagg t" /listShort="yyaD" /GFF_Attribute="listLong" /label="promotor_-35" downshifts complement(4070214) /Source="Nicolas_upshifts" /id="D2121" /incds=0 /nref=32 /ntot=184 /MaxReadThrough="1.8976" /MaxDrop="3.72136" /score="9.09987016" /energy="-7.4" /TU="NA" /idTUdmin="U3230" /TUdmin="-397" /isTUend="FALSE" promotor_-35 4070398..4070403 /Source="Nicolas_upshift_promotors" /id="U3231" /multdbtbs="SigF" /comp="M3" /sig="SigEF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1073 /SigmaFactorBS="tcatgccctctacttttttaaaatctctggtgccatacacaa AGCATAaaaaatcatactgctGGATATACTGTAAACAACCttacataactacacacac c" /listShort="S1576, yyaC" /GFF_Attribute="listLong" /label="promotor_-35" S_feature 4070416..4070497 /Source="Nicolas_S_feature" /locus_tag="new_4204818_4204899" /HighExp="S4, S5, S3, S6, LoTm, S7, T5.0H, BT, M9-stat, T4.0H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigEF" /TUshortPSig="0.999" /TUlongSig="NA" /TUlongPSig="NA" /label="S1576" upshifts 4070416 /Source="Nicolas_upshifts" /id="U3231" /multdbtbs="SigF" /comp="M3" /sig="SigEF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1073 /SigmaFactorBS="tcatgccctctacttttttaaaatctctggtgccatacacaa AGCATAaaaaatcatactgctGGATATACTGTAAACAACCttacataactacacacac c" /listShort="S1576, yyaC" /GFF_Attribute="listLong" promotor_-10 4070419..4070437 /Source="Nicolas_upshift_promotors" /id="U3231" /multdbtbs="SigF" /comp="M3" /sig="SigEF" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=1073 /SigmaFactorBS="tcatgccctctacttttttaaaatctctggtgccatacacaa AGCATAaaaaatcatactgctGGATATACTGTAAACAACCttacataactacacacac c" /listShort="S1576, yyaC" /GFF_Attribute="listLong" /label="promotor_-10" CDS 4070498..4071115 /gene="sprC" /locus_tag="BSU_40950" /old_locus_tag="BSU40950" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 26362088; Product type e : enzyme" /codon_start=1 /transl_table=11 /product="spore-specific protease" /protein_id="NP_391975.1" /db_xref="EnsemblGenomes-Gn:BSU40950" /db_xref="EnsemblGenomes-Tr:CAB16132" /db_xref="InterPro:IPR009665" /db_xref="InterPro:IPR023430" /db_xref="SubtiList:BG10053" /db_xref="UniProtKB/Swiss-Prot:P37521" /translation="MNRKGGLFSSQERVKQYVSHTDAAAAKQIQTILSSSLRKAAGKP IVVVCIGTDRSTGDSLGPLVGMKLKQMQLTRFHVYGTLSDPVHAVNMKDKINDIHKLH KNPFVIAVDACLGRVKSVGSFQIGDGPLKPGAGVQKDLPEVGDLHINGIVNVSGFMEY FVLQNTRLNLVMNMANVLAEGLSLTDRTEWRQERLNPLQRLTGRI*" gene 4070498..4071115 /gene="sprC" /locus_tag="BSU_40950" /old_locus_tag="BSU40950" promotor_-35 4071086..4071094 /Source="Nicolas_upshift_promotors" /id="U3232" /multdbtbs="-" /comp="M5" /sig="Sig-" /pcomp="0.440559440559441" /psig="0.440559440559441" /xcortree=291 /SigmaFactorBS="gaggcaagaacgccttaacCCGTTGCAAaggctcactgggcG CATATAAAATAAAAACCAtcttcgtttgaaagatggttttttcatttatgattctcgt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-35" downshifts 4071105 /Source="Nicolas_upshifts" /id="D2122" /incds=0 /nref=11 /ntot=30 /MaxReadThrough="2.64888" /MaxDrop="3.74502" /score="0.352922387" /energy="-6.6" /TU="NA" /idTUdmin="U3231" /TUdmin=0 /isTUend="TRUE" promotor_-10 4071108..4071126 /Source="Nicolas_upshift_promotors" /id="U3232" /multdbtbs="-" /comp="M5" /sig="Sig-" /pcomp="0.440559440559441" /psig="0.440559440559441" /xcortree=291 /SigmaFactorBS="gaggcaagaacgccttaacCCGTTGCAAaggctcactgggcG CATATAAAATAAAAACCAtcttcgtttgaaagatggttttttcatttatgattctcgt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" /label="promotor_-10" upshifts 4071127 /Source="Nicolas_upshifts" /id="U3232" /multdbtbs="-" /comp="M5" /sig="Sig-" /pcomp="0.440559440559441" /psig="0.440559440559441" /xcortree=291 /SigmaFactorBS="gaggcaagaacgccttaacCCGTTGCAAaggctcactgggcG CATATAAAATAAAAACCAtcttcgtttgaaagatggttttttcatttatgattctcgt t" /GFF_Attribute="listShort" /GFF_Attribute="listLong" CDS complement(4071154..4072002) /gene="parB" /locus_tag="BSU_40960" /old_locus_tag="BSU40960" /function="16.9: Replicate" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:11532141, 12950914, 15659156, 15774898, 15998739, 16677298, 21235642, 28407103" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11532141, 12950914, 15659156, 15774898, 15998739, 16677298, 21235642, 28407103; Product type f: factor" /codon_start=1 /transl_table=11 /product="site-specific DNA-binding protein" /protein_id="NP_391976.1" /db_xref="EnsemblGenomes-Gn:BSU40960" /db_xref="EnsemblGenomes-Tr:CAB16133" /db_xref="GOA:P26497" /db_xref="InterPro:IPR003115" /db_xref="InterPro:IPR004437" /db_xref="InterPro:IPR036086" /db_xref="SubtiList:BG10054" /db_xref="UniProtKB/Swiss-Prot:P26497" /translation="MAKGLGKGINALFNQVDLSEETVEEIKIADLRPNPYQPRKHFDD EALAELKESVLQHGILQPLIVRKSLKGYDIVAGERRFRAAKLAGLDTVPAIVRELSEA LMREIALLENLQREDLSPLEEAQAYDSLLKHLDLTQEQLAKRLGKSRPHIANHLRLLT LPENIQQLIAEGTLSMGHGRTLLGLKNKNKLEPLVQKVIAEQLNVRQLEQLIQQLNQN VPRETKKKEPVKDAVLKERESYLQNYFGTTVNIKRQKKKGKIEIEFFSNEDLDRILEL LSERES*" gene complement(4071154..4072002) /gene="parB" /locus_tag="BSU_40960" /old_locus_tag="BSU40960" downshifts complement(4071174) /Source="Nicolas_upshifts" /id="D2123" /incds=0 /nref=208 /ntot=265 /MaxReadThrough="3.01094" /MaxDrop="5.3801" /score="9.82080496" /energy="-7.9" /TU="U3233" /idTUdmin="U3233" /TUdmin="-257" /isTUend="FALSE" CDS complement(4071995..4072756) /gene="parA" /locus_tag="BSU_40970" /old_locus_tag="BSU40970" /function="16.13: Shape" /function="16.9: Replicate" /experiment="publication(s) with functional evidences, PMID:11532141, 12950914, 15659156, 15774898, 15998739, 16677298, 18077387, 28166228" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11532141, 12950914, 15659156, 15774898, 15998739, 16677298, 18077387, 28166228; Product type f: factor" /codon_start=1 /transl_table=11 /product="chromosome partitioning protein; transcriptionalregulator" /protein_id="NP_391977.1" /db_xref="EnsemblGenomes-Gn:BSU40970" /db_xref="EnsemblGenomes-Tr:CAB16134" /db_xref="GOA:P37522" /db_xref="InterPro:IPR025669" /db_xref="InterPro:IPR027417" /db_xref="SubtiList:BG10055" /db_xref="UniProtKB/Swiss-Prot:P37522" /translation="MGKIIAITNQKGGVGKTTTSVNLGACLAYIGKRVLLVDIDPQGN ATSGLGIEKADVEQCVYDILVDDADVIDIIKATTVENLDVIPATIQLAGAEIELVPTI SREVRLKRALEAVKQNYDYIIIDCPPSLGLLTINALTASDSVVIPVQCEYYALEGLSQ LLNTVRLVQKHLNTDLMIEGVLLTMLDARTNLGIQVIEEVKKYFRDKVYKTVIPRNVR LSEAPSHGKPIILYDPRSRGAEVYLDLAKEVAANG*" gene complement(4071995..4072756) /gene="parA" /locus_tag="BSU_40970" /old_locus_tag="BSU40970" misc_feature complement(4072790..4072809) /Source="Nicolas_upshift_promotors" /id="U3233" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.663336663336663" /psig="0.999000999001" /xcortree=2325 /SigmaFactorBS="attatttcccttctgattcggaacaaaatgatgaaaaaaatg aaacgctttaatcttttTTTGATAGAATAGAAGCAAGatagtacatgttcatgtgaaa g" /listShort="parA, parB" /GFF_Attribute="listLong" /label="promotor_single_box" /note="Geneious type: promotor_single_box" upshifts complement(4072808) /Source="Nicolas_upshifts" /id="U3233" /multdbtbs="-" /comp="M4" /sig="SigA" /pcomp="0.663336663336663" /psig="0.999000999001" /xcortree=2325 /SigmaFactorBS="attatttcccttctgattcggaacaaaatgatgaaaaaaatg aaacgctttaatcttttTTTGATAGAATAGAAGCAAGatagtacatgttcatgtgaaa g" /listShort="parA, parB" /GFF_Attribute="listLong" upshifts complement(4072900) /Source="Nicolas_upshifts" /id="U3234" /multdbtbs="-" /comp="M2" /sig="SigI" /pcomp="0.966033966033966" /psig="0.966033966033966" /xcortree=1771 /SigmaFactorBS="tttttttctttaagaaattccttttttAAGTCAAAAaaacat agaaattGCAGAATTTataagagaaagcataaagcgtgcttgaattttcaattatttc c" /GFF_Attribute="listShort" /listLong="parA, parB" promotor_-10 complement(4072903..4072911) /Source="Nicolas_upshift_promotors" /id="U3234" /multdbtbs="-" /comp="M2" /sig="SigI" /pcomp="0.966033966033966" /psig="0.966033966033966" /xcortree=1771 /SigmaFactorBS="tttttttctttaagaaattccttttttAAGTCAAAAaaacat agaaattGCAGAATTTataagagaaagcataaagcgtgcttgaattttcaattatttc c" /GFF_Attribute="listShort" /listLong="parA, parB" /label="promotor_-10" promotor_-35 complement(4072925..4072933) /Source="Nicolas_upshift_promotors" /id="U3234" /multdbtbs="-" /comp="M2" /sig="SigI" /pcomp="0.966033966033966" /psig="0.966033966033966" /xcortree=1771 /SigmaFactorBS="tttttttctttaagaaattccttttttAAGTCAAAAaaacat agaaattGCAGAATTTataagagaaagcataaagcgtgcttgaattttcaattatttc c" /GFF_Attribute="listShort" /listLong="parA, parB" /label="promotor_-35" promotor_-35 4072937..4072945 /Source="Nicolas_upshift_promotors" /id="U3235" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=500 /SigmaFactorBS="tttctcttataaattctgcaatttctatgtttttttgactta aaAAAGGAATTtcttaaagaaaAAAAGAAGAAGTCACAGTAcagaacgtggaaacagg a" /listShort="yyaB" /GFF_Attribute="listLong" /label="promotor_-35" upshifts 4072953 /Source="Nicolas_upshifts" /id="U3235" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=500 /SigmaFactorBS="tttctcttataaattctgcaatttctatgtttttttgactta aaAAAGGAATTtcttaaagaaaAAAAGAAGAAGTCACAGTAcagaacgtggaaacagg a" /listShort="yyaB" /GFF_Attribute="listLong" promotor_-10 4072957..4072975 /Source="Nicolas_upshift_promotors" /id="U3235" /multdbtbs="-" /comp="M1" /sig="SigH" /pcomp="0.999000999001" /psig="0.999000999001" /xcortree=500 /SigmaFactorBS="tttctcttataaattctgcaatttctatgtttttttgactta aaAAAGGAATTtcttaaagaaaAAAAGAAGAAGTCACAGTAcagaacgtggaaacagg a" /listShort="yyaB" /GFF_Attribute="listLong" /label="promotor_-10" CDS 4073004..4073444 /gene="yyaB" /locus_tag="BSU_40980" /old_locus_tag="BSU40980" /function="16.13: Shape" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 3: Putative function from multiple computational evidences; PubMedId: 15849754, 16850406, 25651892; Product type m: membrane component" /codon_start=1 /transl_table=11 /product="putative antibiotic immunity protein" /protein_id="NP_391978.2" /db_xref="EnsemblGenomes-Gn:BSU40980" /db_xref="EnsemblGenomes-Tr:CAB16135" /db_xref="GOA:P37523" /db_xref="InterPro:IPR009589" /db_xref="SubtiList:BG10056" /db_xref="UniProtKB/Swiss-Prot:P37523" /translation="MVYQTKRDVPVTLMIVFLILLIQADAIVPFVLGNMRVSGWIIFI LLTLLNGLIIWSFIDLKYVLKEHHLIIKAGLIKHQIPYENIDKVVQKKKLWSGFRLIG SRHAITIYYQGGWGHAVISPQKSEEFIHKLKEKNSNIIIFTKSK*" gene 4073004..4073444 /gene="yyaB" /locus_tag="BSU_40980" /old_locus_tag="BSU40980" downshifts 4073393 /Source="Nicolas_upshifts" /id="D2124" /incds=0 /nref=3 /ntot=144 /MaxReadThrough="2.25356" /MaxDrop="3.41185" /score="-0.6683508" /energy="-14.5" /TU="NA" /idTUdmin="U3235" /TUdmin=0 /isTUend="TRUE" CDS complement(4073495..4074346) /gene="nocA" /locus_tag="BSU_40990" /old_locus_tag="BSU40990" /function="16.13: Shape" /function="16.8: Protect" /function="16.9: Replicate" /experiment="publication(s) with functional evidences, PMID:11807071, 15210112, 16549676, 25568309, 28500529" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11807071, 15210112, 16549676, 25568309, 28500529; Product type f: factor" /codon_start=1 /transl_table=11 /product="DNA-binding protein Spo0J-like" /protein_id="NP_391979.1" /db_xref="EnsemblGenomes-Gn:BSU40990" /db_xref="EnsemblGenomes-Tr:CAB16136" /db_xref="GOA:P37524" /db_xref="InterPro:IPR003115" /db_xref="InterPro:IPR004437" /db_xref="InterPro:IPR023705" /db_xref="InterPro:IPR036086" /db_xref="SubtiList:BG10057" /db_xref="UniProtKB/Swiss-Prot:P37524" /translation="MKHSFSRFFGLGEKEQEPEIAEHDTNKEEILEIPVNAIVPNRFQ PRTIFSDEKIKELAMTIHTHGIIQPIVVRHTEEEGQYELIAGERRWRAVQSLEWEKIP AIIKDFSDTETASVALIENLQREELSSIEEAHAYARLLELHDLTQEALAQRLGKGQST IANKLRLLKLPQPVQEAIMEKKITERHARALIPLKQPELQVTLLTEIIEKSLNVKQTE DRVVKMLEQGQRKPKPRRKAFSRDTRIAMNTIRQSLSMVEDSGVKLNTEEEEFEEYIQ LTIRIPK*" gene complement(4073495..4074346) /gene="nocA" /locus_tag="BSU_40990" /old_locus_tag="BSU40990" downshifts complement(4073514) /Source="Nicolas_upshifts" /id="D2125" /incds=0 /nref=245 /ntot=265 /MaxReadThrough="2.30868" /MaxDrop="6.68899" /score="29.5496038" /energy="-14.5" /TU="NA" /idTUdmin="U3236" /TUdmin="-1" /isTUend="TRUE" S_feature complement(4074347..4074467) /Source="Nicolas_S_feature" /locus_tag="new_4208749_4208869_c" /HighExp="LBGstat, G135, G180, H2O2, dia15, G150, Paraq, T0.30H, Oxctl, Diami" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="SigA" /TUlongPSig=1 /label="S1577" CDS complement(4074468..4075187) /gene="rsmG" /locus_tag="BSU_41000" /old_locus_tag="BSU41000" /EC_number="2.1.1.170" /function="16.6: Maintain" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:12001236, 17238915, 17573471, 19622680, 24509311" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12001236, 17238915, 17573471, 19622680, 24509311; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="7-methylguanosine methyltransferase (16S rRNA, nucleotide G527)" /protein_id="NP_391980.1" /db_xref="EnsemblGenomes-Gn:BSU41000" /db_xref="EnsemblGenomes-Tr:CAB16137" /db_xref="GOA:P25813" /db_xref="InterPro:IPR003682" /db_xref="InterPro:IPR029063" /db_xref="PDB:1XDZ" /db_xref="SubtiList:BG10058" /db_xref="UniProtKB/Swiss-Prot:P25813" /translation="MNIEEFTSGLAEKGISLSPRQLEQFELYYDMLVEWNEKINLTSI TEKKEVYLKHFYDSITAAFYVDFNQVNTICDVGAGAGFPSLPIKICFPHLHVTIVDSL NKRITFLEKLSEALQLENTTFCHDRAETFGQRKDVRESYDIVTARAVARLSVLSELCL PLVKKNGLFVALKAASAEEELNAGKKAITTLGGELENIHSFKLPIEESDRNIMVIRKI KNTPKKYPRKPGTPNKSPIEG*" gene complement(4074468..4075187) /gene="rsmG" /locus_tag="BSU_41000" /old_locus_tag="BSU41000" CDS complement(4075201..4077087) /gene="trmF" /locus_tag="BSU_41010" /old_locus_tag="BSU41010" /function="16.6: Maintain" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 11914360, 14993678, 17062623, 26735940; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="tRNA uridine 5-carboxymethylaminomethyl modification enzyme" /protein_id="NP_391981.1" /db_xref="EnsemblGenomes-Gn:BSU41010" /db_xref="EnsemblGenomes-Tr:CAB16138" /db_xref="GOA:P25812" /db_xref="InterPro:IPR002218" /db_xref="InterPro:IPR004416" /db_xref="InterPro:IPR020595" /db_xref="InterPro:IPR026904" /db_xref="InterPro:IPR036188" /db_xref="SubtiList:BG10059" /db_xref="UniProtKB/Swiss-Prot:P25812" /translation="MGYEAGQYDVIVIGAGHAGVEAALASARQGAKTLVLTINLDMVA FMPCNPSVGGPAKGIVVREIDALGGEMGRNIDKTHIQMRMLNTGKGPAVRALRAQADK FQYQHEMKNTLEKEPNLTLLQGIVERLIVEDGECRGVITQTGAHYRAKAVVMTTGTYL RGRIILGDLSYSSGPNNQQPSIKLSEHLEELGFDLVRFKTGTPPRVKSDTIDYSKTEI QPGDDVPRAFSYETVEYITDQLPCWLTYTSPETHEIIDSNLHRSPMYSGMIKGTGPRY CPSIEDKVVRFNDKPRHQIFLEPEGRNTQEVYVQGLSTSLPEDVQQRMLATIPGLENV QMMRAGYAIEYDAIVPTQLWPTLETKKITNLYTAGQINGTSGYEEAAGQGIMAGINAG RKALGKEEVILSRSDAYIGVLIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLRLTE IGHRIGLISDERYAAFEKKKAAIEAEKKRLHSVIIKPSPENQEYIRSLGGSELKDGVR GTDLMKRPEMNYETVTKLAPPEVPVPQDVAEQVEIQVKYEGYIEKSLQQVEKLKKMEN KKIPDRIDYDAIKGIATEARQKLKNVRPLSVAQASRISGVNPADISILLVYLEQGRIA KIAE*" gene complement(4075201..4077087) /gene="trmF" /locus_tag="BSU_41010" /old_locus_tag="BSU41010" CDS complement(4077108..4078487) /gene="mnmE" /locus_tag="BSU_41020" /old_locus_tag="BSU41020" /EC_number="3.6.-.-" /function="16.6: Maintain" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 15522079, 15616586, 19052377, 26735940; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="tRNA modification GTPase and tRNA-U34 5-formylation enzyme" /protein_id="NP_391982.1" /db_xref="EnsemblGenomes-Gn:BSU41020" /db_xref="EnsemblGenomes-Tr:CAB16139" /db_xref="GOA:P25811" /db_xref="InterPro:IPR004520" /db_xref="InterPro:IPR005225" /db_xref="InterPro:IPR006073" /db_xref="InterPro:IPR018948" /db_xref="InterPro:IPR025867" /db_xref="InterPro:IPR027368" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR031168" /db_xref="SubtiList:BG10060" /db_xref="UniProtKB/Swiss-Prot:P25811" /translation="MDTIAAISTPMGEGAIAIVRLSGPEAIQIADKIYKGPKGKTLSS VESHTIHYGHIVDRPSDRVVEEVMVSVLKAPRTFTREDVIEINCHGGIVTVNQVLQLA LREGARLAEPGEFTKRAFLNGRIDLSQAEAVMDLIRAKTDRAMNVAMNQMEGRLSALV RRLRSEILETLAHVEVNIDYPEYDDVEEMTHQILVEKATAVKKEIETLLRTSEQGKIL REGLSTVIIGRPNVGKSSLLNSLVHEAKAIVTDIPGTTRDVIEEYVNVRGVPLRLVDT AGIRETEDIVERIGVERSRQVLKEADLILLVLNYSEELSEEDVKLFEAVEGMDVIVIL NKTDLEPKIDTERVRELANGRPVVTTSLLKEEGINDLEEAIQSLFYTGAIESGDLTYV SNTRHITILQQAKRAIEDALSGIEQDVPIDMVQIDLTRCWELLGEIIGDSVHESLIDQ LFSQFCLGK*" gene complement(4077108..4078487) /gene="mnmE" /locus_tag="BSU_41020" /old_locus_tag="BSU41020" S_feature complement(4078488..4078618) /Source="Nicolas_S_feature" /locus_tag="new_4212890_4213020_c" /HighExp="dia15, Diami, LBGstat, H2O2, Paraq, dia5, G180, T0.30H, LBGexp, G150" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="SigA" /TUlongPSig=1 /label="S1578" promotor_-10 complement(4078610..4078629) /Source="Nicolas_upshift_promotors" /id="U3236" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.596403596403596" /psig=1 /xcortree=2527 /SigmaFactorBS="gataaaaaggaagttcaggaaataaaattAATTGttattcac atgtggaTAAGTTAAAGTAATAAGGGAcgaatttctatttctgtggataacaaatctt c" /listShort="S1578, trmE, trmF, rsmG, S1577, noc" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(4078618) /Source="Nicolas_upshifts" /id="U3236" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.596403596403596" /psig=1 /xcortree=2527 /SigmaFactorBS="gataaaaaggaagttcaggaaataaaattAATTGttattcac atgtggaTAAGTTAAAGTAATAAGGGAcgaatttctatttctgtggataacaaatctt c" /listShort="S1578, trmE, trmF, rsmG, S1577, noc" /GFF_Attribute="listLong" promotor_-35 complement(4078645..4078649) /Source="Nicolas_upshift_promotors" /id="U3236" /multdbtbs="-" /comp="M16" /sig="SigA" /pcomp="0.596403596403596" /psig=1 /xcortree=2527 /SigmaFactorBS="gataaaaaggaagttcaggaaataaaattAATTGttattcac atgtggaTAAGTTAAAGTAATAAGGGAcgaatttctatttctgtggataacaaatctt c" /listShort="S1578, trmE, trmF, rsmG, S1577, noc" /GFF_Attribute="listLong" /label="promotor_-35" promotor_-10 complement(4078673..4078692) /Source="Nicolas_upshift_promotors" /id="U3237" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.995004995004995" /psig=1 /xcortree=2014 /SigmaFactorBS="tctacttttcctagtaatatcaaggttttgCCGTTTAAgttt tttctttttAGGTGTATCCTGTTGATAAAaaggaagttcaggaaataaaattaattgt t" /GFF_Attribute="listShort" /listLong="S1578, trmE, trmF, rsmG, S1577, noc" /label="promotor_-10" upshifts complement(4078683) /Source="Nicolas_upshifts" /id="U3237" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.995004995004995" /psig=1 /xcortree=2014 /SigmaFactorBS="tctacttttcctagtaatatcaaggttttgCCGTTTAAgttt tttctttttAGGTGTATCCTGTTGATAAAaaggaagttcaggaaataaaattaattgt t" /GFF_Attribute="listShort" /listLong="S1578, trmE, trmF, rsmG, S1577, noc" promotor_-35 complement(4078706..4078713) /Source="Nicolas_upshift_promotors" /id="U3237" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.995004995004995" /psig=1 /xcortree=2014 /SigmaFactorBS="tctacttttcctagtaatatcaaggttttgCCGTTTAAgttt tttctttttAGGTGTATCCTGTTGATAAAaaggaagttcaggaaataaaattaattgt t" /GFF_Attribute="listShort" /listLong="S1578, trmE, trmF, rsmG, S1577, noc" /label="promotor_-35" promotor_-35 4078773..4078779 /Source="Nicolas_upshift_promotors" /id="U3238" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.576423576423576" /psig="0.685314685314685" /xcortree=2972 /SigmaFactorBS="atattactaggaaaagtagatttttcggatacaaaaaaaccg aaatccaATTTTTAtcggacttcggtttTATGCTATCTTTTATGGGAAataacgagat g" /listShort="S1579" /GFF_Attribute="listLong" /label="promotor_-35" S_feature 4078784..4081069 /Source="Nicolas_S_feature" /locus_tag="new_4213186_4215471" /HighExp="T0.30H, C30, T1.0H, T1.30H, S2, T0.0H, T-1.10H, T-0.40H, T-1.40H, C90" /AntisenseName="oxaAA" /AntisenseCor="-0.20593684080740801" /AntisenseRegPval="-3.2" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig="0.685" /TUlongSig="NA" /TUlongPSig="NA" /label="S1579" upshifts 4078784 /Source="Nicolas_upshifts" /id="U3238" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.576423576423576" /psig="0.685314685314685" /xcortree=2972 /SigmaFactorBS="atattactaggaaaagtagatttttcggatacaaaaaaaccg aaatccaATTTTTAtcggacttcggtttTATGCTATCTTTTATGGGAAataacgagat g" /listShort="S1579" /GFF_Attribute="listLong" promotor_-10 4078794..4078813 /Source="Nicolas_upshift_promotors" /id="U3238" /multdbtbs="-" /comp="M19" /sig="SigA" /pcomp="0.576423576423576" /psig="0.685314685314685" /xcortree=2972 /SigmaFactorBS="atattactaggaaaagtagatttttcggatacaaaaaaaccg aaatccaATTTTTAtcggacttcggtttTATGCTATCTTTTATGGGAAataacgagat g" /listShort="S1579" /GFF_Attribute="listLong" /label="promotor_-10" CDS complement(4078798..4079424) /gene="jag" /locus_tag="BSU_41030" /old_locus_tag="BSU41030" /function="16.3: Control" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 1487728, 12813085, 26883633, 27776484; Product type f: factor" /codon_start=1 /transl_table=11 /product="SpoIIIJ-associated RNA/ssDNA-binding protein" /protein_id="NP_391983.1" /db_xref="EnsemblGenomes-Gn:BSU41030" /db_xref="EnsemblGenomes-Tr:CAB16140" /db_xref="GOA:Q01620" /db_xref="InterPro:IPR001374" /db_xref="InterPro:IPR004087" /db_xref="InterPro:IPR015946" /db_xref="InterPro:IPR032782" /db_xref="InterPro:IPR034079" /db_xref="InterPro:IPR036867" /db_xref="SubtiList:BG10061" /db_xref="UniProtKB/Swiss-Prot:Q01620" /translation="MRNVTAAGRNVDEAVQSGLQELGLTKDKVEITVIEEGNKGFLGI FGKKPAIVKLVEKIDPIQQAKLYLQTIAEAIAGKSDVTVQESKKTVRYHITGEKAALL IGKRGQTLNALETLTQLALNRYPGQYKNVTVDAENYRLKRKETLSQLAIKLADQVLKT KKSIQLEPMPSSERKIIHDTLSGYANHQIKTYSMGEGENRHLVISHKR*" gene complement(4078798..4079424) /gene="jag" /locus_tag="BSU_41030" /old_locus_tag="BSU41030" downshifts complement(4078815) /Source="Nicolas_upshifts" /id="D2126" /incds=0 /nref=229 /ntot=258 /MaxReadThrough="2.29192" /MaxDrop="6.32351" /score="24.2602773" /energy="-14.1" /TU="NA" /idTUdmin="U3239" /TUdmin=0 /isTUend="TRUE" CDS complement(4079421..4080206) /gene="oxaAA" /locus_tag="BSU_41040" /old_locus_tag="BSU41040" /function="16.13: Shape" /experiment="publication(s) with functional evidences, PMID:11889108, 12586834, 15654078, 15671040, 15849754, 15995216, 16850406, 24739968, 25133632, 25313395, 25359772, 25855636" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 11889108, 12586834, 15654078, 15671040, 15849754, 15995216, 16850406, 24739968, 25133632, 25313395, 25359772, 25855636; Product type f: factor" /codon_start=1 /transl_table=11 /product="Sec-independent factor for membrane protein insertion (YidC/SpoIIIJ family)" /protein_id="NP_391984.1" /db_xref="EnsemblGenomes-Gn:BSU41040" /db_xref="EnsemblGenomes-Tr:CAB16141" /db_xref="GOA:Q01625" /db_xref="InterPro:IPR001708" /db_xref="InterPro:IPR023060" /db_xref="InterPro:IPR028055" /db_xref="SubtiList:BG10062" /db_xref="UniProtKB/Swiss-Prot:Q01625" /translation="MLLKRRIGLLLSMVGVFMLLAGCSSVKEPITADSPHFWDKYVVY PLSELITYVAKLTGDNYGLSIILVTILIRLLILPLMIKQLRSSKAMQALQPEMQKLKE KYSSKDQKTQQKLQQETMALFQKHGVNPLAGCFPILIQMPILIGFYHAIMRTQAISEH SFLWFDLGEKDPYYILPIVAGVATFVQQKLMMAGNAQQNPQMAMMLWIMPIMIIVFAI NFPAALSLYWVVGNLFMIAQTFLIKGPDIKKNPEPQKAGGKKK*" gene complement(4079421..4080206) /gene="oxaAA" /locus_tag="BSU_41040" /old_locus_tag="BSU41040" promotor_-10 complement(4080251..4080270) /Source="Nicolas_upshift_promotors" /id="U3239" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.999000999001" /psig=1 /xcortree=2262 /SigmaFactorBS="taaaagcgcttcctttctggttgatcagaaaaagaCACCATT taaaactgaaaGATGCTAAAATACATACAAGtatgctttgcaataaaagagtgtaaag a" /listShort="oxaAA, jag" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(4080263) /Source="Nicolas_upshifts" /id="U3239" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.999000999001" /psig=1 /xcortree=2262 /SigmaFactorBS="taaaagcgcttcctttctggttgatcagaaaaagaCACCATT taaaactgaaaGATGCTAAAATACATACAAGtatgctttgcaataaaagagtgtaaag a" /listShort="oxaAA, jag" /GFF_Attribute="listLong" S_feature complement(4080265..4080350) /Source="Nicolas_S_feature" /locus_tag="new_4214667_4214752_c" /HighExp="G135, G180, H2O2, Oxctl, Paraq, G150, Cold, LPh, LBGexp, C30" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="0.993, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S1580" promotor_-35 complement(4080282..4080288) /Source="Nicolas_upshift_promotors" /id="U3239" /multdbtbs="SigA" /comp="M4" /sig="SigA" /pcomp="0.999000999001" /psig=1 /xcortree=2262 /SigmaFactorBS="taaaagcgcttcctttctggttgatcagaaaaagaCACCATT taaaactgaaaGATGCTAAAATACATACAAGtatgctttgcaataaaagagtgtaaag a" /listShort="oxaAA, jag" /GFF_Attribute="listLong" /label="promotor_-35" CDS complement(4080351..4080701) /gene="rnpA" /locus_tag="BSU_41050" /old_locus_tag="BSU41050" /EC_number="3.1.26.5" /function="16.6: Maintain" /function="16.2: Construct biomass (Anabolism)" /inference="ab initio prediction:AMIGene:2.0" /note="Evidence 2a: Function from experimental evidences in other organisms; PubMedId: 12682299, 16061811, 16163391, 16980484, 17299131, 21347352, 24580115; Product type e: enzyme" /codon_start=1 /transl_table=11 /product="protein component of ribonuclease P (RNase P) (substrate specificity)" /protein_id="NP_391985.1" /db_xref="EnsemblGenomes-Gn:BSU41050" /db_xref="EnsemblGenomes-Tr:CAB16142" /db_xref="GOA:P25814" /db_xref="InterPro:IPR000100" /db_xref="InterPro:IPR014721" /db_xref="InterPro:IPR020539" /db_xref="InterPro:IPR020568" /db_xref="PDB:1A6F" /db_xref="PDB:4JG4" /db_xref="SubtiList:BG10063" /db_xref="UniProtKB/Swiss-Prot:P25814" /translation="MKKRNRLKKNEDFQKVFKHGTSVANRQFVLYTLDQPENDELRVG LSVSKKIGNAVMRNRIKRLIRQAFLEEKERLKEKDYIIIARKPASQLTYEETKKSLQH LFRKSSLYKKSSSK*" gene complement(4080351..4080701) /gene="rnpA" /locus_tag="BSU_41050" /old_locus_tag="BSU41050" S_feature complement(4080702..4080852) /Source="Nicolas_S_feature" /locus_tag="new_4215104_4215254_c" /HighExp="G135, G180, Oxctl, H2O2, Paraq, Cold, G150, C30, LPh, HPh" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA, SigA" /TUshortPSig="0.993, 1" /TUlongSig="NA" /TUlongPSig="NA" /label="S1581" CDS complement(4080853..4080987) /gene="rpmH" /locus_tag="BSU_41060" /old_locus_tag="BSU41060" /function="16.2: Construct biomass (Anabolism)" /experiment="publication(s) with functional evidences, PMID:7539334, 9371771, 12682299, 23002217, 25182490" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7539334, 9371771, 12682299, 23002217, 25182490; Product type s: structure" /codon_start=1 /transl_table=11 /product="ribosomal protein L34" /protein_id="NP_391986.1" /db_xref="EnsemblGenomes-Gn:BSU41060" /db_xref="EnsemblGenomes-Tr:CAB16143" /db_xref="GOA:P05647" /db_xref="InterPro:IPR000271" /db_xref="InterPro:IPR020939" /db_xref="PDB:3J3V" /db_xref="PDB:3J3W" /db_xref="PDB:3J9W" /db_xref="PDB:5NJT" /db_xref="SubtiList:BG10064" /db_xref="UniProtKB/Swiss-Prot:P05647" /translation="MKRTFQPNNRKRSKVHGFRSRMSSKNGRLVLARRRRKGRKVLSA *" gene complement(4080853..4080987) /gene="rpmH" /locus_tag="BSU_41060" /old_locus_tag="BSU41060" promotor_no_box 4081011..4081111 /Source="Nicolas_upshift_promotors" /id="U3241" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.467532467532468" /psig="0.047952047952048" /xcortree=1495 /SigmaFactorBS="agctgttaaagacagtcttacttattatatttgcgttaccta ttcattgtcaacttcactagtgcttttatttcttgcaaccataataggataccatacc t" /listShort="S1583" /GFF_Attribute="listLong" /label="promotor_no_box" promotor_-10 complement(4081023..4081042) /Source="Nicolas_upshift_promotors" /id="U3240" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.587412587412587" /psig="0.993006993006993" /xcortree=2640 /SigmaFactorBS="tggttgcaagaaataaaagcactagtgaAGTTGACAatgaat aggtaacgcAAATATAATAAGTAAGACTGtctttaacagctattcctcgagggaggtg t" /listShort="rpmH, S1581, rnpA, S1580, oxaAA, jag" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(4081033) /Source="Nicolas_upshifts" /id="U3240" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.587412587412587" /psig="0.993006993006993" /xcortree=2640 /SigmaFactorBS="tggttgcaagaaataaaagcactagtgaAGTTGACAatgaat aggtaacgcAAATATAATAAGTAAGACTGtctttaacagctattcctcgagggaggtg t" /listShort="rpmH, S1581, rnpA, S1580, oxaAA, jag" /GFF_Attribute="listLong" S_feature complement(4081035..4081103) /Source="Nicolas_S_feature" /locus_tag="new_4215437_4215505_c" /HighExp="Oxctl, G180, Paraq, H2O2, LBGstat, GM 120, MG-0.2, HPh, G135, G150" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="SigA" /TUshortPSig=1 /TUlongSig="NA" /TUlongPSig="NA" /label="S1582" promotor_-35 complement(4081058..4081065) /Source="Nicolas_upshift_promotors" /id="U3240" /multdbtbs="SigA" /comp="M14" /sig="SigA" /pcomp="0.587412587412587" /psig="0.993006993006993" /xcortree=2640 /SigmaFactorBS="tggttgcaagaaataaaagcactagtgaAGTTGACAatgaat aggtaacgcAAATATAATAAGTAAGACTGtctttaacagctattcctcgagggaggtg t" /listShort="rpmH, S1581, rnpA, S1580, oxaAA, jag" /GFF_Attribute="listLong" /label="promotor_-35" S_feature 4081071..>4081204 /Source="Nicolas_S_feature" /locus_tag="new_4215473_4215670" /HighExp="T0.30H, C30, T1.0H, T1.30H, T0.0H, T-0.40H, S2, T-1.10H, Pyr, T-1.40H" /AntisenseName="NA" /AntisenseCor="NA" /AntisenseRegPval="NA" /CDS_PredictionProba="NA" /TUshortSig="Sig-" /TUshortPSig="0.048" /TUlongSig="NA" /TUlongPSig="NA" /label="S1583" upshifts 4081071 /Source="Nicolas_upshifts" /id="U3241" /multdbtbs="-" /comp="M13" /sig="Sig-" /pcomp="0.467532467532468" /psig="0.047952047952048" /xcortree=1495 /SigmaFactorBS="agctgttaaagacagtcttacttattatatttgcgttaccta ttcattgtcaacttcactagtgcttttatttcttgcaaccataataggataccatacc t" /listShort="S1583" /GFF_Attribute="listLong" promotor_-10 complement(4081089..4081108) /Source="Nicolas_upshift_promotors" /id="U3242" /multdbtbs="SigA" /comp="M16" /sig="SigA" /pcomp="0.99000999000999" /psig=1 /xcortree=2591 /SigmaFactorBS="cttttttccgtaaaattaaggaatctaaaaaataaGGTTTcg aaagttgaaaaggTATGGTATCCTATTATGGTTgcaagaaataaaagcactagtgaag t" /listShort="S1582, rpmH, S1581, rnpA, S1580, oxaAA, jag" /GFF_Attribute="listLong" /label="promotor_-10" upshifts complement(4081103) /Source="Nicolas_upshifts" /id="U3242" /multdbtbs="SigA" /comp="M16" /sig="SigA" /pcomp="0.99000999000999" /psig=1 /xcortree=2591 /SigmaFactorBS="cttttttccgtaaaattaaggaatctaaaaaataaGGTTTcg aaagttgaaaaggTATGGTATCCTATTATGGTTgcaagaaataaaagcactagtgaag t" /listShort="S1582, rpmH, S1581, rnpA, S1580, oxaAA, jag" /GFF_Attribute="listLong" promotor_-35 complement(4081124..4081128) /Source="Nicolas_upshift_promotors" /id="U3242" /multdbtbs="SigA" /comp="M16" /sig="SigA" /pcomp="0.99000999000999" /psig=1 /xcortree=2591 /SigmaFactorBS="cttttttccgtaaaattaaggaatctaaaaaataaGGTTTcg aaagttgaaaaggTATGGTATCCTATTATGGTTgcaagaaataaaagcactagtgaag t" /listShort="S1582, rpmH, S1581, rnpA, S1580, oxaAA, jag" /GFF_Attribute="listLong" /label="promotor_-35" ORIGIN 1 atctttttcg gcttttttta gtatccacag aggttatcga caacattttc acattaccaa 61 cccctgtgga caaggttttt tcaacaggtt gtccgctttg tggataagat tgtgacaacc 121 attgcaagct ctcgtttatt ttggtattat atttgtgttt taactcttga ttactaatcc 181 tacctttcct ctttatccac aaagtgtgga taagttgtgg attgatttca cacagcttgt 241 gtagaaggtt gtccacaagt tgtgaaattt gtcgaaaagc tatttatcta ctatattata 301 tgttttcaac atttaatgtg tacgaatggt aagcgccatt tgctcttttt ttgtgttcta 361 taacagagaa agacgccatt ttctaagaaa aggagggacg tgccggaaga tggaaaatat 421 attagacctg tggaaccaag cccttgctca aatcgaaaaa aagttgagca aaccgagttt 481 tgagacttgg atgaagtcaa ccaaagccca ctcactgcaa ggcgatacat taacaatcac 541 ggctcccaat gaatttgcca gagactggct ggagtccaga tacttgcatc tgattgcaga 601 tactatatat gaattaaccg gggaagaatt gagcattaag tttgtcattc ctcaaaatca 661 agatgttgag gactttatgc cgaaaccgca agtcaaaaaa gcggtcaaag aagatacatc 721 tgattttcct caaaatatgc tcaatccaaa atatactttt gatacttttg tcatcggatc 781 tggaaaccga tttgcacatg ctgcttccct cgcagtagcg gaagcgcccg cgaaagctta 841 caacccttta tttatctatg ggggcgtcgg cttagggaaa acacacttaa tgcatgcgat 901 cggccattat gtaatagatc ataatccttc tgccaaagtg gtttatctgt cttctgagaa 961 atttacaaac gaattcatca actctatccg agataataaa gccgtcgact tccgcaatcg 1021 ctatcgaaat gttgatgtgc ttttgataga tgatattcaa tttttagcgg ggaaagaaca 1081 aacccaggaa gaatttttcc atacatttaa cacattacac gaagaaagca aacaaatcgt 1141 catttcaagt gaccggccgc caaaggaaat tccgacactt gaagacagat tgcgctcacg 1201 ttttgaatgg ggacttatta cagatatcac accgcctgat ctagaaacga gaattgcaat 1261 tttaagaaaa aaggccaaag cagagggcct cgatattccg aacgaggtta tgctttacat 1321 cgcgaatcaa atcgacagca atattcggga actcgaagga gcattaatca gagttgtcgc 1381 ttattcatct ttaattaata aagatattaa tgctgatctg gccgctgagg cgttgaaaga 1441 tattattcct tcctcaaaac cgaaagtcat tacgataaaa gaaattcaga gggtagtagg 1501 ccagcaattt aatattaaac tcgaggattt caaagcaaaa aaacggacaa agtcagtagc 1561 ttttccgcgt caaatcgcca tgtacttatc aagggaaatg actgattcct ctcttcctaa 1621 aatcggtgaa gagtttggag gacgtgatca tacgaccgtt attcatgcgc atgaaaaaat 1681 ttcaaaactg ctggcagatg atgaacagct tcagcagcat gtaaaagaaa ttaaagaaca 1741 gcttaaatag caggaccggg gatcaatcgg ggaaagtgtg aataactttt cggaagtcat 1801 acacagtctg tccacatgtg gataggctgt gtttcctgtc tttttcacaa cttatccaca 1861 aatccacagg ccctactatt acttctacta ttttttataa atatatatat taatacatta 1921 tccgttagga ggataaaaat gaaattcacg attcaaaaag atcgtcttgt tgaaagtgtc 1981 caagatgtat taaaagcagt ttcatccaga accacgattc ccattctgac tggtattaaa 2041 attgttgcat cagatgatgg agtatccttt acagggagtg actcagatat ttctattgaa 2101 tccttcattc caaaagaaga aggagataaa gaaatcgtca ctattgaaca gcccggaagc 2161 atcgttttac aggctcgctt ttttagtgaa attgtaaaaa aattgccgat ggcaactgta 2221 gaaattgaag tccaaaatca gtatttgacg attatccgtt ctggtaaagc tgaatttaat 2281 ctaaacggac tggatgctga tgaatatccg cacttgccgc agattgaaga gcatcatgcg 2341 attcagatcc caactgattt gttaaaaaat ctaatcagac aaacagtatt tgcagtgtcc 2401 acctcagaaa cacgccctat cttgacaggt gtaaactgga aagtggagca aagtgaatta 2461 ttatgcactg caacggatag ccaccgtctt gcattaagaa aggcgaaact tgatattcca 2521 gaagacagat cttataacgt cgtgattccg ggaaaaagtt taactgaact cagcaagatt 2581 ttagatgaca accaggaact tgtagatatc gtcatcacag aaacccaagt tctgtttaaa 2641 gcgaaaaacg tcttgttctt ctcacggctt ctggacggga attatccaga cacaaccagc 2701 ctgattccgc aagacagcaa aacagaaatc attgtgaaca caaaagaatt ccttcaggcc 2761 attgatcgtg catctctttt agctagagag ggacgcaaca acgttgtaaa actgtccgca 2821 aaaccggctg aatccattga aatttcttcc aattcgccag aaatcggtaa agttgtggaa 2881 gcaattgttg cggatcaaat tgaaggtgag gaattaaata tctcttttag tccaaaatat 2941 atgctggatg cactaaaggt gcttgaagga gcagaaatac gcgtaagctt tacaggcgca 3001 atgagacctt tcttaattcg cacgccgaat gatgaaacga ttgtacagct tatccttcct 3061 gtcagaacct attaatccga tacactgctg ccgacccgtc ggcagctttt ctattcggta 3121 tctgctccga caagttttcc ctttccctaa ttcgtttttt tttagtacaa ttagatatta 3181 gtgatatttg aaagaggtcg atataatggc aaatccgatt tcaattgata cagagatgat 3241 tacactcgga caattcttaa aattagccga tgtgattcag tctggcggta tggcgaagtg 3301 gtttttaagc gagcatgaag tgcttgtgaa cgatgagccg gacaaccgcc ggggcagaaa 3361 gctgtatgtt ggagatgtgg tagagattga aggatttggt tcatttcaag tcgtcaatta 3421 aagcgggtga cactgattgt atatccagaa cttagaactg acatcttacc gcaactacga 3481 ccatgctgaa cttcaatttg aaaataaagt aaatgtgatc atcggagaaa acgcccaggg 3541 gaagacaaac ctcatggagg cgatctatgt cttgtccatg gcgaaatcgc accggacatc 3601 aaatgacaaa gaacttatac ggtgggacaa agactatgct aaaatagagg gaagagtgat 3661 gaagcaaaac ggggcgatcc cgatgcagct cgtcatctcc aaaaagggta aaaagggcaa 3721 ggtcaatcat attgaacagc aaaagctcag ccagtatgtc ggggccctca acaccattat 3781 gttcgcgccg gaagatttaa atcttgtaaa gggaagccct caagtgagaa ggcggtttct 3841 tgacatggaa atcggacagg tttctcccgt ctaccttcat gatctttctc tttaccagaa 3901 aatcctttcc cagcggaatc attttttgaa acagctgcaa acaagaaaac aaactgaccg 3961 gacgatgctc gatgttctga ccgatcagct tgtagaagtt gcagcaaaag tcgtcgtaaa 4021 acgcctgcag tttacagcac agctcgagaa atgggcgcag cccatccatg caggcatctc 4081 aagagggctt gaagaactga ccctgaaata ccatacagct cttgatgtat cagatcccct 4141 agatttgtcg aaaataggag atagctatca agaagcgttt tctaaattaa gagaaaaaga 4201 aattgagcgt ggtgtgacgc tgtcagggcc tcatcgcgat gatgttcttt tctatgtgaa 4261 cggacgcgat gtgcagacgt atggttctca aggacagcag cgaacgacgg cgttgtccct 4321 taagctggcg gagattgacc tgatccatga agaaatcgga gaatatccca ttttactatt 4381 ggatgatgta ctgagtgaac tggatgatta tcgccagtca cacttgcttc atacgatcca 4441 aggccgtgta caaacgtttg tcacaacgac aagcgttgat ggcattgatc acgaaacctt 4501 acgtcaagca ggaatgttcc gtgtgcaaaa tggtgcgtta gtgaagtgaa gaaatgaggt 4561 gagcaattgt atattcattt aggtgatgac tttgtggttt caacacgaga tattgtcggc 4621 atttttgact ttaaagccaa catgtcgcct attgttgaag aatttctgaa aaaacagaaa 4681 cacaaggtgg tgccttccgt aaacggcacg cccaaatcta tcgtagtcac ggttcagaat 4741 atatattact ctcccttatc ttccagcaca ttaaaaaaac gtgcgcaatt tatgtttgaa 4801 atagattctt agaaattttt tatcacgaat atatcgttta gaaaagtgta ggtgaatgac 4861 gtggctatgg aacagcagca aaacagttat gatgaaaatc agatacaggt actagaagga 4921 ttggaagctg ttcgtaaaag accggggatg tatatcggtt cgacaaacag caaaggcctt 4981 caccacttgg tatgggaaat tgtcgacaat agtattgacg aagccctcgc cggttattgt 5041 acggatatca atatccaaat cgaaaaagac aacagtatca cggttgtaga taatggccgc 5101 ggtattccag tcggtattca tgaaaaaatg ggccgtcctg cggtagaagt cattatgacg 5161 gtgcttcatg ccggaggaaa atttgacgga agcggctata aagtatccgg aggattacac 5221 ggtgtaggtg cgtcggtcgt aaacgcacta tcaacagagc ttgatgtgac ggttcaccgt 5281 gacggtaaaa ttcaccgcca aacctataaa cgcggagttc cggttacaga ccttgaaatc 5341 attggcgaaa cggatcatac aggaacgacg acacattttg tcccggaccc tgaaattttc 5401 tcagaaacaa ccgagtatga ttacgatctg cttgccaacc gcgtgcgtga attagccttt 5461 ttaacaaagg gcgtaaacat cacgattgaa gataaacgtg aaggacaaga gcgcaaaaat 5521 gaataccatt acgaaggcgg aattaaaagt tatgtagagt atttaaaccg ctctaaagag 5581 gttgtccatg aagagccgat ttacattgaa ggcgaaaagg acggcattac ggttgaagtg 5641 gctttgcaat acaatgacag ctacacaagc aacatttact cgtttacaaa caacattaac 5701 acgtacgaag gcggtaccca tgaagctggc ttcaaaacgg gcctgactcg tgttatcaac 5761 gattacgcca gaaaaaaagg gcttattaaa gaaaatgatc caaacctaag cggagatgac 5821 gtaagggaag ggctgacagc gattatttca atcaaacacc ctgatccgca gtttgagggc 5881 caaacaaaaa caaagctggg caactcagaa gcacggacga tcaccgatac gttattttct 5941 acggcgatgg aaacatttat gctggaaaat ccagatgcag ccaaaaaaat tgtcgataaa 6001 ggtttaatgg cggcaagagc aagaatggct gcgaaaaaag cgcgtgaact aacacgccgt 6061 aagagtgctt tggaaatttc aaacctgccc ggtaagttag cggactgctc ttcaaaagat 6121 ccgagcatct ccgagttata tatcgtagag ggtgactctg ccggaggatc tgctaaacaa 6181 ggacgcgaca gacatttcca agccattttg ccgcttagag gtaaaatcct aaacgttgaa 6241 aaggccagac tggataaaat cctttctaac aacgaagttc gctctatgat cacagcgctc 6301 ggcacaggta tcggagaaga cttcaacctt gagaaagccc gttaccacaa agttgtcatt 6361 atgacagatg ccgatgttga cggcgcgcac atcagaacac tgctgttaac gttcttttac 6421 agatatatgc gccaaattat cgaaaatggc tacgtgtaca ttgcgcagcc gccgctctac 6481 aaggttcaac aggggaaacg cgttgaatat gcatacaatg acaaggagct tgaagagctg 6541 ttaaaaactc ttcctcaaac gcctaagcct ggactgcagc gttacaaagg tcttggtgaa 6601 atgaatgcca cccagctatg ggagacaacc atggatccta gctccagaac acttcttcag 6661 gtaactcttg aagatgcaat ggatgcggat gagacttttg aaatgcttat gggcgacaag 6721 gtagaaccgc gccgaaactt catagaagcg aatgcgagat acgttaaaaa tcttgacatc 6781 taatcataaa aagccttatt tccaataaga aataaggctt ttttctgaac aagatcagat 6841 gcagcgatgc ctgcaatacc tatatattct agcaatttaa tgtgtataat cataagttta 6901 ttgatataat ggagaatagt gaaatcgtat tgaaggtcat aatggacaat ctactcccac 6961 atatttcatg tgatacttca gggaggtttt ttaatgagtg aacaaaacac accacaagtt 7021 cgtgaaataa atatcagtca ggaaatgcgt acgtccttct tggattatgc aatgagcgtt 7081 atcgtgtccc gtgctcttcc ggatgttcgt gacggtttaa aaccggttca tagacggatt 7141 ttgtatgcaa tgaatgattt aggcatgaca agtgacaagc cttataaaaa atccgcgcgt 7201 atcgttggag aagttatcgg gaaataccac ccgcacggtg attcagcggt atatgaatcc 7261 atggtcagaa tggctcagga tttcaactac cgttatatgc tcgttgacgg tcacggaaac 7321 ttcggttctg ttgacggaga ctcagcggcg gccatgcgtt atacagaagc acgaatgtct 7381 aaaatctcaa tggagattct tcgcgacatc acaaaagaca caatcgatta ccaggataac 7441 tatgacgggt cagaaagaga acctgtcgtt atgccttcaa ggttcccgaa tctgctcgtg 7501 aacggtgctg ccggcattgc ggtaggtatg gcaacaaaca ttcctccgca ccagctggga 7561 gaaatcattg acggtgtact tgctgttagt gagaatccgg acattacaat tccagagctt 7621 atggaagtca ttccagggcc tgatttcccg accgcgggtc aaatcttggg acgcagcggt 7681 atccggaaag catacgaatc aggccgaggc tctatcacga tccgggcaaa agctgagatc 7741 gaacaaacat cttcgggtaa agaaagaatt atcgttacag agttacctta ccaagtaaat 7801 aaggcgaaat taattgagaa aattgctgat ctcgtaaggg acaaaaagat agagggtatc 7861 acagatctgc gtgatgagtc agatcgtaca ggtatgagaa ttgtcattga aatcagacgc 7921 gatgccaatg cgaatgttat cttaaacaat ctgtacaaac aaactgctct acaaacatct 7981 tttggcatca acctgcttgc gcttgttgat ggccagccga aagttttaac tcttaagcaa 8041 tgcctggagc attaccttga ccatcaaaaa gttgtcatta gacgccgtac tgcttatgaa 8101 ttgcgtaaag cagaagcgag agctcatatc ttggaaggat tgagagttgc actggatcat 8161 ctcgatgcag ttatctccct tatccgtaat tctcaaacgg ctgaaattgc gagaacaggt 8221 ttaattgaac aattctcact gacagagaag caagcacaag cgatccttga catgaggctc 8281 cagcgtttaa cgggactgga acgtgaaaag atcgaagaag aataccagtc tcttgttaaa 8341 ttaattgcag agctaaaaga catcttggca aatgaatata aagtgcttga gatcattcgt 8401 gaagaactca cggaaatcaa agagcgtttt aacgatgaaa gacgtactga gatcgtcact 8461 tctggactgg agacaattga agatgaagat ctcatcgaga gagaaaatat cgtagttact 8521 ctgacgcaca acggatacgt caaacgtctt cctgcatcaa cttaccgcag tcaaaaacgg 8581 ggcggaaaag gtgtacaagg tatgggaaca aacgaagatg atttcgttga acatttgatc 8641 tctacgtcaa ctcatgacac gattctcttc ttctcgaaca aggggaaagt gtatcgtgca 8701 aaagggtatg aaatccctga atacggcaga acggcaaaag gaatcccgat tattaacctg 8761 ctggaggtag aaaagggtga gtggatcaac gcgattattc cagtcacgga attcaatgcg 8821 gagctttacc tcttcttcac tacaaagcat ggggtttcaa aacgaacatc gctatctcaa 8881 ttcgctaata tccgcaacaa tggtctaatt gctctgagtc ttcgtgaaga tgatgaactg 8941 atgggtgtac gtctgactga cggcacaaaa caaatcatca ttggaacgaa aaacggttta 9001 ctgattcgtt tccctgaaac agatgtccga gagatgggaa gaactgcggc gggcgtaaaa 9061 ggcatcaccc tgacggatga cgacgttgtt gtcggcatgg agattttaga ggaagaatca 9121 cacgtcctta tcgtaactga aaaagggtac ggaaaacgaa ctcctgctga agagtacaga 9181 acccaaagcc ggggcggaaa aggactcaaa acagcgaaaa tcaccgagaa caacggccaa 9241 ctagtagcag tgaaagctac taaaggtgaa gaggatctaa tgattattac agctagcggc 9301 gtactcatca gaatggacat caatgatatc tccatcaccg gacgtgtcac tcaaggtgtg 9361 cgtctcatca gaatggcaga agaagagcat gttgctacag tagctttagt tgagaaaaac 9421 gaagaagatg agaatgaaga agaacaagaa gaagtgtgaa aaaaagcgca gctgaaatag 9481 ctgcgctttt ttgtgtcata accctttaca gtcataaaaa ttatggtata atcatttctg 9541 ttgtcttttt aaagacacaa gcatgaccat tatgactagt aaaaactttt tcaaaaaagt 9601 attgacctag ttaactaaaa atgttactat taagtagtcg ctttgagaga agcacacaaa 9661 gttctttgaa aactaaacaa gacaaaacgt acctgttaat tcatttttat aaatcgcaca 9721 gcgatgtgcg tagtcagtca aactagggcc tgcacgacgc aggtcacaca ggtgtcgccg 9781 caggatgcgg tgaacttaac ctgtgatcca tttatcggag agtttgatcc tggctcagga 9841 cgaacgctgg cggcgtgcct aatacatgca agtcgagcgg acagatggga gcttgctccc 9901 tgatgttagc ggcggacggg tgagtaacac gtgggtaacc tgcctgtaag actgggataa 9961 ctccgggaaa ccggggctaa taccggatgg ttgtttgaac cgcatggttc aaacataaaa 10021 ggtggcttcg gctaccactt acagatggac ccgcggcgca ttagctagtt ggtgaggtaa 10081 cggctcacca aggcgacgat gcgtagccga cctgagaggg tgatcggcca cactgggact 10141 gagacacggc ccagactcct acgggaggca gcagtaggga atcttccgca atggacgaaa 10201 gtctgacgga gcaacgccgc gtgagtgatg aaggttttcg gatcgtaaag ctctgttgtt 10261 agggaagaac aagtgccgtt cgaatagggc ggtaccttga cggtacctaa ccagaaagcc 10321 acggctaact acgtgccagc agccgcggta atacgtaggt ggcaagcgtt gtccggaatt 10381 attgggcgta aagggctcgc aggcggtttc ttaagtctga tgtgaaagcc cccggctcaa 10441 ccggggaggg tcattggaaa ctggggaact tgagtgcaga agaggagagt ggaattccac 10501 gtgtagcggt gaaatgcgta gagatgtgga ggaacaccag tggcgaaggc gactctctgg 10561 tctgtaactg acgctgagga gcgaaagcgt ggggagcgaa caggattaga taccctggta 10621 gtccacgccg taaacgatga gtgctaagtg ttagggggtt tccgcccctt agtgctgcag 10681 ctaacgcatt aagcactccg cctggggagt acggtcgcaa gactgaaact caaaggaatt 10741 gacgggggcc cgcacaagcg gtggagcatg tggtttaatt cgaagcaacg cgaagaacct 10801 taccaggtct tgacatcctc tgacaatcct agagatagga cgtccccttc gggggcagag 10861 tgacaggtgg tgcatggttg tcgtcagctc gtgtcgtgag atgttgggtt aagtcccgca 10921 acgagcgcaa cccttgatct tagttgccag cattcagttg ggcactctaa ggtgactgcc 10981 ggtgacaaac cggaggaagg tggggatgac gtcaaatcat catgcccctt atgacctggg 11041 ctacacacgt gctacaatgg acagaacaaa gggcagcgaa accgcgaggt taagccaatc 11101 ccacaaatct gttctcagtt cggatcgcag tctgcaactc gactgcgtga agctggaatc 11161 gctagtaatc gcggatcagc atgccgcggt gaatacgttc ccgggccttg tacacaccgc 11221 ccgtcacacc acgagagttt gtaacacccg aagtcggtga ggtaaccttt taggagccag 11281 ccgccgaagg tgggacagat gattggggtg aagtcgtaac aaggtagccg tatcggaagg 11341 tgcggctgga tcacctcctt tctaaggata ttttacggaa tataagacct tgggtcttat 11401 aaacagaacg ttccctgtct tgtttagttt tgaaggaact ttgttccttg aataagttaa 11461 gatgggcctg tagctcagct ggttagagcg cacgcctgat aagcgtgagg tcggtggttc 11521 gagtccactc aggcccacca tcttatataa cggggcctta gctcagctgg gagagcgcct 11581 gctttgcacg caggaggtca gcggttcgat cccgctaggc tccaccaacg tgttctttga 11641 aaactagata acagtagaca tcacattcaa ttagtaacac aagatatcac atagtgattc 11701 tttttaacgg ttaagttaga aagggcgcac ggtggatgcc ttggcactag gagccgatga 11761 aggacgggac gaacaccgat atgcttcggg gagctgtaag caagctttga tccggagatt 11821 tccgaatggg gaaacccacc actcgtaatg gagtggtatc catatctgaa ttcataggat 11881 atgagaaggc agacccgggg aactgaaaca tctaagtacc cggaggaaga gaaagcaaat 11941 gcgattccct gagtagcggc gagcgaaacg ggatcagccc aaaccaagag gcttgcctct 12001 tggggttgta ggacactctg tacggagtta caaaggaacg aggtagatga agaggtctgg 12061 aaaggcccgc cataggaggt aacagccctg tagtcaaaac ttcgttctct cctgagtgga 12121 tcctgagtac ggcggaacac gtgaaattcc gtcggaatcc gggaggacca tctcccaagg 12181 ctaaatactc cctagtgacc gatagtgaac cagtaccgtg agggaaaggt gaaaagcacc 12241 ccggaagggg agtgaaagag atcctgaaac cgtgtgccta caagtagtca gagcccgtta 12301 acgggtgatg gcgtgccttt tgtagaatga accggcgagt tacgatctcg tgcaaggtta 12361 agcagaagat gcggagccgc agcgaaagcg agtctgaata gggcgcatga gtacgtggtc 12421 gtagacccga aaccaggtga tctacccatg tccagggtga agttcaggta acactgaatg 12481 gaggcccgaa cccacgcacg ttgaaaagtg cggggatgag gtgtgggtag gggtgaaatg 12541 ccaatcgaac ctggagatag ctggttctct ccgaaatagc tttagggcta gcctcaaggt 12601 aagagtcttg gaggtagagc actgattgga ctaggggccc ctaccgggtt accgaattca 12661 gtcaaactcc gaatgccaat gacttatcct tgggagtcag actgcgagtg ataagatccg 12721 tagtcgaaag ggaaacagcc cagaccgcca gctaaggtcc caaagtatac gttaagtgga 12781 aaaggatgtg gagttgctta gacaaccagg atgttggctt agaagcagcc accatttaaa 12841 gagtgcgtaa tagctcactg gtcgagtgac tctgcgccga aaatgtaccg gggctaaacg 12901 tatcaccgaa gctgcggact gttcttcgaa cagtggtagg agagcgttct aagggctgtg 12961 aagccagacc ggaaggactg gtggagcgct tagaagtgag aatgccggta tgagtagcga 13021 aagaggggtg agaatcccct ccaccgaatg cctaaggttt cctgaggaag gctcgtccgc 13081 tcagggttag tcgggaccta agccgaggcc gaaaggcgta ggcgatggac aacaggttga 13141 tattcctgta ccacctcctc accatttgag caatgggggg acgcaggagg atagggtaag 13201 cgcggtattg gatatccgcg tccaagcagt taggctggga aataggcaaa tccgtttccc 13261 ataaggctga gctgtgatgg cgagcgaaat atagtagcga agttcctgat tccacactgc 13321 caagaaaagc ctctagcgag gtgagaggtg cccgtaccgc aaaccgacac aggtaggcga 13381 ggagagaatc ctaaggtgat cgagagaact ctcgttaagg aactcggcaa aatgaccccg 13441 taacttcggg agaaggggtg ctctgttagg gtgcaagccc gagagagccg cagtgaatag 13501 gcccaggcga ctgtttagca aaaacacagg tctctgcgaa gccgtaaggc gaagtatagg 13561 ggctgacgcc tgcccggtgc tggaaggtta agaggagcgc ttagcgtaag cgaaggtgcg 13621 aattgaagcc ccagtaaacg gcggccgtaa ctataacggt cctaaggtag cgaaattcct 13681 tgtcgggtaa gttccgaccc gcacgaaagg cgcaacgatc tgggcactgt ctcaacgaga 13741 gactcggtga aattatagta cctgtgaaga tgcaggttac ccgcgacagg acggaaagac 13801 cccgtggagc tttactgcag cctgatattg aatgttggta cagcttgtac aggataggta 13861 ggagccttgg aaaccggagc gccagcttcg gtggaggcat cggtgggata ctaccctggc 13921 tgtattgacc ttctaacccg ccgcccttat cgggcgggga gacagtgtca ggtgggcagt 13981 ttgactgggg cggtcgcctc ctaaaaggta acggaggcgc ccaaaggttc cctcagaatg 14041 gttggaaatc attcgcagag tgtaaaggca caagggagct tgactgcgag acctacaagt 14101 cgagcaggga cgaaagtcgg gcttagtgat ccggtggttc cgcatggaag ggccatcgct 14161 caacggataa aagctacccc ggggataaca ggcttatctc ccccaagagt ccacatcgac 14221 ggggaggttt ggcacctcga tgtcggctca tcgcatcctg gggctgtagt cggtcccaag 14281 ggttgggctg ttcgcccatt aaagcggtac gcgagctggg ttcagaacgt cgtgagacag 14341 ttcggtccct atccgtcgcg ggcgcaggaa atttgagagg agctgtcctt agtacgagag 14401 gaccgggatg gacgcaccgc tggtgtacca gttgttctgc caagggcatc gctgggtagc 14461 tatgtgcgga cgggataagt gctgaaagca tctaagcatg aagcccccct caagatgaga 14521 tttcccattc cgcaaggaag taagatccct gaaagatgat caggttgata ggtctgaggt 14581 ggaagtgtgg cgacacatgg agctgacaga tactaatcga tcgaggactt aaccatattt 14641 ttgaatgatg tcacacctgt tatctagttt tgagagaaca ctctcaattt gtttggtggc 14701 gatagcgaag aggtcacacc cgttcccata ccgaacacgg aagttaagct cttcagcgcc 14761 gatggtagtc gggggtttcc ccctgtgaga gtaggacgcc gccaagcaag cttaaaccca 14821 gctcaatgag ctgggttttt tgtttgttaa aaatgaagaa gaaactgtga agcgtattta 14881 gggaatttct tttctgatac taataaaaac tgctgaatta acacgtagtc atcacttata 14941 tgctgtgtta ataactcata ccaccattct gtttcatacc ttgcaatcat cccaacgttg 15001 tacaaaatca aataatgaat tgtcatttcg ggaagcctca gaaattgctc cctttgagaa 15061 gggatataat attggttctt ttccatgtca aacaataagc tggtcgatgt ccatggctcc 15121 ttgtcttgtg gtgaaatttc gaacagcagc ccgtgttcat ttttttttgt aaaagaccat 15181 tgataatgat gggacatgta ttcagcaaac cttgaatcag acattttgta attgattact 15241 acttcctccg gtacaaaaat ttcgttctta tccttctcaa cttttgtcat aaatcgttct 15301 ttctgctgaa agtagaaaat atcgctaagt tctggaatgg ccattaataa ttttttcatg 15361 gtataccgtt catctactat atccgattgt ccgaataaat gtttcataaa atgtacgcat 15421 aggccattcc gttgtatttt cacttcatcg tcgctaaaac aataattttg tttctttcgt 15481 tttcttgttg ttacgccatg tgccagtact gatgtatggc ttggataatg aggatcacgt 15541 gtaattaagc atgctttgat aagctgtgcc attccataaa ataaaagaat cggtttgatt 15601 tctaagggag aatatgcggc ttgtttataa aacgattcgg catgctttaa gaaataaata 15661 aaccgttcac tgtttttaaa agagtttttt ttcgcatcgt taataccgtt taagatataa 15721 accttttcta gaaatttctg ggttgattca acggagtaaa atagcgctaa gtctttccac 15781 tcatgatatg tcatgtatat ttcttaatcc tttccgttat ctaaatattt caactctttc 15841 ccgcttcctt gacatgctct tggctagttg ataatctaca tataatattt tgccgaaaag 15901 agggggattt actaatgtgg gaaagtaaat tttcaaaaga aggcttaacg ttcgacgatg 15961 tgctgcttgt accagcaaag tctgaggtac ttccgcgtga tgtggattta tctgtagaac 16021 ttacaaaaac gttaaagcta aatattcctg tcatcagcgc aggtatggac actgtaacag 16081 aatcagcaat ggcaattgca atggcaagac agggcggctt gggcatcatt cacaaaaata 16141 tgtccattga acagcaggct gaacaagttg ataaagtaaa gcgttctgag cgcggcgtta 16201 tcacaaatcc cttcttttta actcctgatc accaagtatt tgatgcggag catttgatgg 16261 ggaaatacag aatttccggt gttccgattg taaataacga agaagaccag aagcttgttg 16321 gaattattac aaaccgtgac cttcgtttta tttctgacta ctcaatgaaa atcagcgacg 16381 tcatgacgaa agaagagcta gttactgcat ctgtaggaac tactctggat gaagctgaaa 16441 agattttgca gaaacataaa attgaaaagc ttcctctcgt agatgaccag aataaattaa 16501 aaggtcttat cacaattaaa gacattgaaa aagtcattga gttcccgaac tcatctaaag 16561 acattcacgg ccgcctgatc gttggcgcgg cagttggtgt aactggcgat acaatgactc 16621 gcgtcaaaaa gcttgttgaa gccaatgttg atgtgattgt tatcgataca gctcacggac 16681 actctcaagg cgttttaaac acagtcacaa aaatccgtga aacgtatccc gaattaaaca 16741 ttattgctgg aaacgtggca acagctgaag cgacaagagc gcttatcgaa gctggagcag 16801 acgttgtcaa agttggaata gggcctggtt caatttgtac tacacgtgtt gtagccggcg 16861 tgggtgttcc gcaaattaca gcaatttatg attgtgcgac tgaagcaaga aaacacggca 16921 aaacaatcat cgccgacggt gggattaaat tctctggcga tatcactaaa gcattggcag 16981 ccggcggaca tgctgttatg ctcggaagct tgcttgcagg cacatcagaa agccctggtg 17041 aaactgaaat ctaccaaggc agaagattta aggtataccg cggcatggga tcagttgctg 17101 caatggaaaa aggaagtaaa gaccgttact tccaagaaga aaacaaaaaa tttgttcctg 17161 aaggaattga aggacgcaca ccttacaaag ggccagttga agaaaccgtt tatcagctag 17221 tcggaggcct tcgttctggt atggggtatt gcgggtccaa agatctgcgt gcgctaagag 17281 aagaagctca gttcattcgc atgactggcg caggacttcg cgaaagccat ccgcatgacg 17341 tacagattac aaaagaatca cctaactata caatttcata ataaattgtt acaaattaaa 17401 aacatttgac agggtctctg actctgtcta ttttttttat actgattatg ataaaattta 17461 tactgttgtg cattgaaaat gtccttaacg gcttaattat agatgaagaa aatgaaatac 17521 ggaggtcgta cgattgaaca tcaagaaatg taaacagcta ctgatgtcat tggttgtgtt 17581 aactctagct gtcacgtgtc tggctccaat gtcaaaagcg aaagcagcca gcgatccaat 17641 tgatatcaat gcatctgctg ctattatgat cgaagcttct tcaggtaaaa ttctttacag 17701 taaaaatgca gataagagac tgccaattgc gagtatgaca aaaatgatga cagagtatct 17761 gttattggaa gcaattgatc aaggtaaagt gaaatgggac caaacctata cgcctgatga 17821 ctatgtgtat gaaatttccc aagataacag cttatcaaac gttcctcttc ggaaagacgg 17881 gaaatacaca gtaaaagaat tatatcaagc tacagcaatt tattctgcaa atgctgctgc 17941 tattgcgatt gcagaaatcg ttgccggttc tgaaactaag tttgttgaaa aaatgaatgc 18001 aaaagcaaaa gaactaggct taacagatta caaatttgtt aacgcaacag gtcttgaaaa 18061 caaagatctt cacgggcatc agcctgaggg gacaagcgta aatgaagaaa gtgaagtttc 18121 tgcaaaggat atggcggttc ttgcggatca cttgattact gactaccctg agatactgga 18181 gacttccagt atcgccaaaa cgaaattcag agaaggcacc gatgatgaaa tggacatgcc 18241 gaactggaat tttatgctga aggggcttgt cagcgagtat aaaaaagcga ctgtagacgg 18301 actgaaaaca ggttctactg actctgcggg ttcatgcttt acaggaacag ctgaacgcaa 18361 cggtatgcgt gtcatcactg ttgttttaaa cgcaaagggc aaccttcata caggccgttt 18421 cgatgaaacg aaaaaaatgt ttgattatgc tttcgacaat ttctccatga aagaaattta 18481 tgctgaaggc gatcaagtaa aaggccataa aacaatttca gttgataagg gtaaagagaa 18541 agaagtaggc attgtgacaa acaaggcgtt ctctcttcct gtcaaaaatg gtgaagaaaa 18601 gaattacaaa gcgaaggtca cactgaataa agacaactta actgctcctg tgaaaaaagg 18661 aaccaaggtt gggaagctga ctgcggaata cacaggtgat gaaaaggatt acggattcct 18721 taacagcgat ctggctggcg tagaccttgt tacaaaagaa aatgtagaaa aagcaaactg 18781 gtttgttttg acaatgcgca gtatcggcgg attttttgcc ggaatttggg gaagcattgt 18841 tgatacggta accggctggt tttaatcaat tgaaagagct ctgatggatg ttagggctct 18901 ttcgcgtaat atactgaaaa aacccaattt ttaataaaaa atgattttca aagcgctaaa 18961 aaccgaataa aatagtatat atgcatatga attattggat ttctaggata caataaggat 19021 tagaaatcat ataactatac cttgattagg gggaccaaga aatggctcaa acaggtactg 19081 aacgtgtaaa acgcggaatg gcagaaatgc aaaaaggcgg cgtcatcatg gacgtcatca 19141 atgcggaaca agcgaaaatc gctgaagaag ctggagctgt cgctgtaatg gcgctagaac 19201 gtgtgccagc agatattcgc gcggctggag gagttgcccg tatggctgac cctacaatcg 19261 tggaagaagt aatgaatgca gtatctatcc cggtaatggc aaaagcgcgt atcggacata 19321 ttgttgaagc gcgtgtgctt gaagctatgg gtgttgacta tattgatgaa agtgaagttc 19381 tgacgccggc tgacgaagaa tttcatttaa ataaaaatga atacacagtt ccttttgtct 19441 gtggctgccg tgatcttggt gaagcaacac gccgtattgc ggaaggtgct tctatgcttc 19501 gcacaaaagg tgagcctgga acaggtaata ttgttgaggc tgttcgccat atgcgtaaag 19561 ttaacgctca agtgcgcaaa gtagttgcga tgagtgagga tgagctaatg acagaagcga 19621 aaaacctagg tgctccttac gagcttcttc ttcaaattaa aaaagacggc aagcttcctg 19681 tcgttaactt tgccgctggc ggcgtagcaa ctccagctga tgctgctctc atgatgcagc 19741 ttggtgctga cggagtattt gttggttctg gtatttttaa atcagacaac cctgctaaat 19801 ttgcgaaagc aattgtggaa gcaacaactc actttactga ttacaaatta atcgctgagt 19861 tgtcaaaaga gcttggtact gcaatgaaag ggattgaaat ctcaaactta cttccagaac 19921 agcgtatgca agaacgcggc tggtaagaac ataggagcgc tgctgacatg ttaacaatag 19981 gtgtactagg acttcaagga gcagttagag agcacatcca tgcgattgaa gcatgcggcg 20041 cggctggtct tgtcgtaaaa cgtccggagc agctgaacga agttgacggg ttgattttgc 20101 cgggcggtga gagcacgacg atgcgccgtt tgatcgatac gtatcaattc atggagccgc 20161 ttcgtgaatt cgctgctcag ggcaaaccga tgtttggaac atgtgccgga ttaattatat 20221 tagcaaaaga aattgccggt tcagataatc ctcatttagg tcttctgaat gtggttgtag 20281 aacgtaattc atttggccgg caggttgaca gctttgaagc tgatttaaca attaaaggct 20341 tggacgagcc ttttactggg gtattcatcc gtgctccgca tattttagaa gctggtgaaa 20401 atgttgaagt tctatcggag cataatggtc gtattgtagc cgcgaaacag gggcaattcc 20461 ttggctgctc attccatccg gagctgacag aagatcaccg agtgacgcag ctgtttgttg 20521 aaatggttga ggaatataag caaaaggcac ttgtataaaa cagttgaaag ctgtggaaac 20581 ttatagtaca ttataagcac aaataaagat cgaaaagcgt tgataggaac tagtagggag 20641 cctctctttc taagagagcc gatggttggt gcgaatcggt gaaagatgct gtctgaatcc 20701 atccttgagc gaaatgctga agcgagtagg catttacggg ataaccgtta tgtttgaaag 20761 tggaaaacga gtctttgatt tgttttcaat cagggtggca acgcgagagc tctcgtccct 20821 ttatggggat gagggctctt tttattttcg ataaatcaat aaaaaaagga gtgtttcgca 20881 tgcttgatac gaaaatgctg agagcaaatt ttcaagaaat taaagcaaag cttgtacaca 20941 aaggcgaaga cttaactgat tttgataagt ttgaggcgct ggatgataga cgaagagagc 21001 ttatcggcaa ggttgaagag ttaaaaggaa aacgaaatga agtttctcag caggttgctg 21061 tgctgaagcg tgagaaaaaa gacgcggatc acattattaa agaaatgcgt gaagtcggcg 21121 aggaaattaa aaagctcgat gaagaattac ggacagtgga agctgagctt gatacaatcc 21181 tgctctcaat cccgaatatt ccgcatgagt ctgtacctgt cggtgaaaca gaagacgaca 21241 acgtagaagt gcgtaaatgg ggtgaaaagc cttcatttgc ttatgagccg aagccgcact 21301 gggatattgc ggatgagctg ggtattctgg attttgaacg tgctgccaaa gtaacaggaa 21361 gccgtttcgt gttctataaa ggcttaggtg ctcgtctgga gcgtgcgctt tataacttta 21421 tgcttgatct gcatgtggat gagtataact acactgaagt gatcccgcca tatatggtaa 21481 accgcgcaag catgacggga acggggcagc ttcctaaatt tgaagaggat gcatttaaaa 21541 tcagagaaga agattatttc ttaattccaa cggcggaagt gccgattaca aacatgcatc 21601 gcgatgaaat cctttcaggt gacagcctgc cgatcaacta tgcggcattc agtgcttgct 21661 tccgttctga agctggttca gcaggacgtg acacacgcgg attaattcgt cagcaccaat 21721 ttaataaagt tgagcttgta aagtttgtga agcctgaaga ttcttatgaa gaattagaga 21781 aacttacaaa ccaagcagaa cgggttcttc agctgcttga gcttccatac cgtgtcatga 21841 gcatgtgtac gggtgactta ggctttacgg ctgcgaaaaa atacgatatc gaagtttgga 21901 ttccaagcca agacacatat cgagaaatct cttcttgcag caacttcgaa gcgttccagg 21961 cgagacgtgc gaatattcgt ttcagacgtg aagcgaaagg caagcctgag catgtacaca 22021 cactgaacgg ctcaggactg gcggttggaa gaacagttgc tgctatctta gaaaattatc 22081 agcaggaaga cggaagcgtt gtgattccga aagtgcttcg tccttatatg gggaatagag 22141 aagtaatgaa accgtaaatt atggaaaggc gtgcctgaca aggtgcgcct ttttgcttat 22201 gtaaacacgg cattttcata aaaacaaaaa aagtttttaa aaatgcttga ccacacgaga 22261 acatacgtga tatagttagt cttgtcgata cggaggaata cccaagtccg gctgaaggga 22321 tcggtcttga aaaccgacag gggtgtcaaa gcccgcgggg gttcgaatcc ctcttcctcc 22381 gccatattga ttttaattct aatgaaacac aagcatatat tggagattgt tttgtccgtt 22441 gcattcggtg cggcggattt tttattttaa agaaaaagtg aatctcgact gagattcact 22501 ttttttgatt atcatgaata actgaagcaa tttgatctac aatattttca atcgagtttt 22561 cgtcgttcag aagatcataa tcttcaatgc gaagttttaa aacagggcag gcattaaaac 22621 cgcttatcca gttctcgtag cgtgtatgca tttcttccca ataagaccgg cttgtctgaa 22681 gctccatctc acggccgcgt tgttcaatcc ggtttaaaat gttctccaga tctccttcta 22741 aatagatcaa cacatctgga tgtgggaaat acggtgtcat taccattgct tcgaaaaggc 22801 ttgtgtaagt cttataatca acctttgaca ttgtcccttt atcagcatgc atttttgcga 22861 aaattcctgt atcttcataa atcgaacgat cctgtacaaa acctccgccg gcttcaaaaa 22921 ttgttttctg ttctttgaag cgttcagcta agaagtaaat ttgaaggtga aagctccaac 22981 gttcaaaatc atgatagaac ttttccaaat atggattatg atcgacttcc tccaacgatg 23041 ttttaaatcc aagccgttta gctaaagttt ttgttaaagt cgattttccg acacctactg 23101 ttcctgctac tgtaataatt gaattcttag ggatatgatg ttccttcata cgataagctc 23161 ctttacatgg gcggcaatgc gttcaaagtc gctcttattc aaaacgaaat cctttgaatc 23221 accatctacg gttaacactg taagttcagg gtctgcttcc tgcagctgct tgatggcgac 23281 ttcataatct gaaatcagct gctccaaata gctagtttca atttttttct caaaggggcg 23341 cccgcgtttt tcaatgcggt gtagcaatgt aggcagactg gcctttatgt aaatgatgaa 23401 attcggcttt ggcagatcat ccgttagcag gtgatatatc tttttgtatt tttccagctg 23461 atgtggagac aaggttcgtt ccgcaaaaat cacattttta taaatatgat aatcagctat 23521 tacaggctgt ccctttttta aaaagtgatc actggtgtct tcaagctgtt tgtatctgtg 23581 acaaagaaaa aacatctcga gctggaagct ccattccttt atattgtcat aaaacttatc 23641 aaggtacggg ttatcctcta caatctcatt gatcataggg aatccgaatt tttgtgagag 23701 catcgttgcg agagttgttt ttcctgcccc gataggacct tctattgcaa taaaaggggc 23761 tgtattcatc ggaatcctcc ttatatctga aaaacgtgcg tcagttaccg accttcatat 23821 tgtatcacaa cccttgggtg cccccatgaa aaaaagacgt ttccaaatta tcgaaacgtc 23881 tttttgacaa cattaaattg atcagacagc agcagccagt tttgtggaaa ggaaagaccc 23941 agcttccaat agctgatgcc tcttaaattc agctctttaa tcagattgaa ttttgcttga 24001 atcgagcggg catcctcgaa ccatacctcg tgccttctgt tttctgcatc agtatagcgg 24061 aagaaaggag cttgagcggt ttggtcatac tgaatggaag cattgttctg atcagctatg 24121 acaatggctt gctgagggct tactgctctt gctggagttc cccctgctgt atatggcagc 24181 gtccagtcat atccatataa attctggccc atgacaattt tgttcgcagg catttcagtc 24241 aaagcatatt ctatgacatc acggacaggt ccaattggag aaaccgcttg aggcggtccg 24301 ccgctatagc cccattcata tgtcatgaga acaacaaagt cgacaatttc gccatgtgcc 24361 ctgtaatcat gagcttcata ccacctgccc tgctgtgttg cacttgtttt aggagcaaga 24421 gccgtagaaa tttctaagcc ctctcgatgg aaaagatccc ttgcttcgcg gaggaattga 24481 ttataggcct ctctatcctg gggccgcaaa tattcaaagt cgaaatgaat gtcacggaag 24541 ccatatcttc tggcattctc gactatttca tttagaagcc gtctttttac agtttcgtcg 24601 ttcaaaagga tccggccaag ttcatcgctg aatgcctggt tttctaggtt cgttataatc 24661 atcatcaatg ttgtattttg actttctgta atgctcctta aattcgttaa aggcggtgcg 24721 actaaggttc cgttccgctg tgcctggaag ctgaatgcgc caaggtaagt taagtagggc 24781 gacgcttctc tggccgcctg ctggagattt tcgctgactt gatttcctcg gggctccaaa 24841 taagcatttg attcgatgtc tcgtttagga gctggaggga tgtataaacg gaaaccaatc 24901 tgaagcacgg tatttaactg gatgcggtta acccttgcga gctcggctgc tgttgtattg 24961 aactgccggg cgatggatgt cagggtatca cctcgcttca catcatagaa ctggccagct 25021 attggaatga caatggtttg tccgacaaca aggctgtcgg gattcggtat ttcattcgtt 25081 tcagtgatgt catttgtggt tgttctgtat tgtgaagcga tagcagaaag agtgtcgcct 25141 tgttttacca cataaatttg aatgaaaaac gcctcctttc atatcgctat caatgtatga 25201 aagaaaagcg ctgatcatgt ttatttttct ataatttgtt cttccgtcgt aatttctgcg 25261 aaaagaacat tctccatcat ggttaaggcg aattcgttat cttcgtcact gtttgacgcg 25321 atacagtcct taggaatcgt gatgctgtat tccctcatat aagcgtcatt agcggtaaac 25381 agcacgcata tattgccggc tatacctgtt atgataatat gtctcacctg caactcagta 25441 agaagggtgt gaagtgctgt ttcgtagaaa gcggaatgtt tcggtttgat taaaaaataa 25501 tcagcatcta ccggagctat ctttgtgatg atatccttgc ttctttcatt tgtgcattct 25561 tgctgtatgt ttttaatgtc agcttgccaa agtccataat gatcattgat gtaaataatc 25621 ggccattcat tttgtctcgc gtgctccttt aatgataaaa tatgaggaac gattttttct 25681 gtttttttag cgagggtttc ccccatatcg aattcaaaat tattgatcat gtctacaatg 25741 agaagggctt tatctgcttt ggacaatcga cagtctcctt tccgtttcag ttatagttaa 25801 tatgtagcct ttttaggcaa tgaaaaaact ttgaaaagag agcttatcct tatgacacaa 25861 gatgaacttt atatgaaaga agcaattaaa gaagcgaaaa aggctgaaga gaaaggtgaa 25921 gtgccaatag gtgcggtgct tgtcattaat ggtgaaatta tagcgcgtgc gcataattta 25981 agagagactg aacagcgatc tattgcccat gcagaaatgc ttgtaattga tgaagcgtgt 26041 aaggcactcg gaacatggcg gctggaaggt gcgactcttt atgtgacgct tgagccttgt 26101 ccaatgtgtg ctggtgcagt cgtactttct cgagtggaaa aagtggtttt tggcgcattt 26161 gatccgaaag gcggctgttc aggcacgcta atgaaccttc ttcaggagga acgctttaat 26221 catcaggctg aagtggtgag cggtgtgctt gaggaagaat gcggcggaat gctcagtgcg 26281 tttttcagag aactaagaaa aaagaagaaa gccgccagga aaaacttgtc tgaatagtac 26341 ggttgcaatt tttaggggaa acagatatac ttaagtgtgc atcgtaatag atgcaacata 26401 aaatttgata tttattttgc cgtgctaagc ggggaggtag cggtgccctg tacctgcaat 26461 ccgctctagc agggccgaat cccttctcga ggttcgttta ctttaaggcc tgccttaagt 26521 aagtggtgtt gacgtttggg tcctgcgcaa tgggaattca tgaaccatgt caggtccgga 26581 aggaagcagc attaagtgaa acctctcatg tgccgcaggg ttgcctgggc cgagctaact 26641 gcttaagtaa cgcttagggt agcgaatcga cagaaggtgc acggtaaatc aatcatcaaa 26701 ttttcagact cacctaatat taggtgagtt ttttgttatg taaaaagagc ttttggaatc 26761 gaaacaaggt tcatgtataa tgggaatgat gaataacgga ggagggcaaa cccgtgagtt 26821 accaagcttt atatcgagta ttcaggcctc agcgctttga agatgtggtc ggacaagaac 26881 acattacaaa aacgctgcaa aatgcccttt tgcaaaaaaa gttttctcac gcctatctgt 26941 tttccgggcc tagaggaacc ggaaaaacca gtgcagccaa aatatttgct aaggctgtca 27001 actgtgaaca tgctcctgtt gatgagccat gcaacgaatg tgcggcctgt aaagggataa 27061 caaacgggtc aatatccgat gtcatagaaa ttgacgccgc ttctaataac ggtgttgatg 27121 agattcgtga cattcgcgat aaagtgaagt ttgccccatc ggccgtcaca tataaggtat 27181 atatcataga tgaggtgcat atgctttcta tcggcgcttt taatgcatta ctaaaaacat 27241 tagaagagcc gcctgagcat tgtattttca tattagcaac aactgaaccg cacaaaattc 27301 ctttaaccat tatctctaga tgtcagcgtt ttgactttaa acgaattacc tcccaagcga 27361 ttgtaggccg catgaataaa attgttgatg ctgaacagct gcaagtggag gaaggatcgc 27421 tggaaatcat cgcgagtgct gcagacggag ggatgaggga tgccctgagc cttcttgatc 27481 aggccatatc attcagcggc gatatcctga aagtcgaaga tgcgctttta attacgggtg 27541 ctgtttctca attatatatc gggaagcttg caaaatccct gcatgataaa aacgtttctg 27601 acgcactgga aacattaaat gaattgcttc agcaaggaaa agatccagct aagctgatag 27661 aagatatgat tttctatttc agggacatgc tgctgtacaa aacagcccct ggcttagagg 27721 gagtgcttga gaaagtaaaa gtcgatgaaa cgttccggga actaagtgaa caaattccgg 27781 ctcaggccct atatgaaatg attgatattc tgaacaagag ccatcaggaa atgaaatgga 27841 caaatcatcc gcgtatcttt ttcgaagtgg ccgttgtgaa gatttgccaa acctcacatc 27901 aatctgctgc tgatctcccg gaagtggata tgctgatgaa aaaaatccag cagctcgaac 27961 aggaagtaga gcggctcaaa acaacgggca taaaagcagc tgcggaaagc ccgaaaaaag 28021 aagcgccgcg tgtgccaaag ggcgggaaat ccaattacaa agcgccagta ggcagaattc 28081 atgagatttt gaaggaagcc acaagaccgg atcttgatct gctcagaaac agttggggca 28141 agcttcttgc tcatctcaaa cagcaaaaca aagtatcaca tgccgctttg ctgaatgaca 28201 gtgaacctgt ggctgccgga tcggcggcat ttgttctgaa attcaaatat gaaattcatt 28261 gtaaaatggt cgctgaggat aacaacggag tccggactaa tcttgagcag attttagaat 28321 cgatgctcgg aaaaagaatg gatttgattg gcgttccaga agcacaatgg ggtaaaataa 28381 gagaagaatt tttagaagat catcagcagg aaaatgaagg atcaaatgaa ccggctgaag 28441 aagacccgct tattgccgaa gcgaaaaagc ttgttggagc ggatttaatt gaaataaaag 28501 actaacaaaa tgaaagagag tgaatgctat gcgtggcgga atgggtaata tgcaaaaaat 28561 gatgaaacaa atgcaaaaaa tgcaaaagga catggcgaag gctcaagaag agcttgcaga 28621 aaaggttgtt gaaggaactg caggcggcgg tatggtaaca gtaaaagcaa acggccaaaa 28681 agaaatcctg gatgttatca tcaaagaaga agtcgttgat cctgaagata ttgatatgct 28741 tcaagattta gtgcttgctg caacgaatga agctttgaaa aaagttgacg aaatcacaaa 28801 cgaaacaatg ggtcaattta caaagggaat gaacatgcca ggtttattct agggggataa 28861 aagaacatgc aatatcctga accaatatca aagctgattg acagctttat gaaattgcca 28921 gggatcggac cgaaaacagc ggttcgtctg gctttttttg ttctaggtat gaaagaagat 28981 gtagtattag attttgcgaa agcattagta aatgcgaaac gcaacctgac atattgttca 29041 gtttgcgggc atattacaga tcaggaccct tgctatatat gtgaagatac gcgcagggat 29101 aagtctgtta tctgtgttgt gcaagaccct aaagacgtta tcgctatgga gaaaatgaag 29161 gaatacaacg gacagtatca cgttcttcac ggcgctattt ctccaatgga cggcatcgga 29221 ccggaggata ttaaaatacc agaattgtta aaacgattac aggatgatca agtgacagaa 29281 gtgatcctcg cgacaaaccc taatatagaa ggggaagcaa cagcgatgta tatatcaagg 29341 ctcctcaagc cgtctggtat taagctctcc cgtattgccc acggactgcc cgtcggcggt 29401 gatttggaat atgctgatga ggtcactctt tctaaagcac ttgaaggaag acgtgaattg 29461 taaggaggaa aaagcgatcc atgggttttc ttcgcaagaa aacattaaga agagagtttg 29521 atgaaaaact aaccgagcag ctttttaagc aaaaggaaga gtggaacagg caaaaaaagc 29581 tggttgaaaa aagcttagaa ccgtctgctg aagtgttata cgaactgaaa gtagctgaag 29641 cgaagtattt tttttactta agggaagcga agcagcgaaa tttaaaaatc agccggtgga 29701 agtaagtggt ctaaactcct ggatcttctc ataagcttgt actagaacaa gcgaaggaga 29761 tgagaagatt catggagcct atttttatta ttgggattat tttaggactg gttattcttc 29821 tttttttatc aggttcagca gcgaagcctt taaagtggat tggcatcaca gctgttaaat 29881 ttgtggcagg tgctttgctg ctggtttgtg taaatatgtt tggcggcagt cttggcattc 29941 atgtgccgat taatctggtt acaacagcta tcagcggaat tttaggaata cccggaatag 30001 ctgcgttagt cgtcattaag caatttatca tttaattgat attatgtatt gacttagaca 30061 actgaaggtg ttattctaat atacgtcgct gatgacgaac agcttttttg aaaagaaaat 30121 gctaaaaagt tgttgacagt agcggcggta aatgttatga taataaagtc gcttaaacga 30181 gcggtaaaca aagttctttg aaaactaaac aagacaaaac gtacctgtta attcattttt 30241 ataaatcgca cagcaatgtg cgtagtcagt caaactactt tatcggagag tttgatcctg 30301 gctcaggacg aacgctggcg gcgtgcctaa tacatgcaag tcgagcggac agatgggagc 30361 ttgctccctg atgttagcgg cggacgggtg agtaacacgt gggtaacctg cctgtaagac 30421 tgggataact ccgggaaacc ggggctaata ccggatggtt gtttgaaccg catggttcaa 30481 acataaaagg tggcttcggc taccacttac agatggaccc gcggcgcatt agctagttgg 30541 tgaggtaacg gctcaccaag gcgacgatgc gtagccgacc tgagagggtg atcggccaca 30601 ctgggactga gacacggccc agactcctac gggaggcagc agtagggaat cttccgcaat 30661 ggacgaaagt ctgacggagc aacgccgcgt gagtgatgaa ggttttcgga tcgtaaagct 30721 ctgttgttag ggaagaacaa gtaccgttcg aatagggcgg taccttgacg gtacctaacc 30781 agaaagccac ggctaactac gtgccagcag ccgcggtaat acgtaggtgg caagcgttgt 30841 ccggaattat tgggcgtaaa gggctcgcag gcggtttctt aagtctgatg tgaaagcccc 30901 cggctcaacc ggggagggtc attggaaact ggggaacttg agtgcagaag aggagagtgg 30961 aattccacgt gtagcggtga aatgcgtaga gatgtggagg aacaccagtg gcgaaggcga 31021 ctctctggtc tgtaactgac gctgaggagc gaaagcgtgg ggagcgaaca ggattagata 31081 ccctggtagt ccacgccgta aacgatgagt gctaagtgtt agggggtttc cgccccttag 31141 tgctgcagct aacgcattaa gcactccgcc tggggagtac ggtcgcaaga ctgaaactca 31201 aaggaattga cgggggcccg cacaagcggt ggagcatgtg gtttaattcg aagcaacgcg 31261 aagaacctta ccaggtcttg acatcctctg acaatcctag agataggacg tccccttcgg 31321 gggcagagtg acaggtggtg catggttgtc gtcagctcgt gtcgtgagat gttgggttaa 31381 gtcccgcaac gagcgcaacc cttgatctta gttgccagca ttcagttggg cactctaagg 31441 tgactgccgg tgacaaaccg gaggaaggtg gggatgacgt caaatcatca tgccccttat 31501 gacctgggct acacacgtgc tacaatggac agaacaaagg gcagcgaaac cgcgaggtta 31561 agccaatccc acaaatctgt tctcagttcg gatcgcagtc tgcaactcga ctgcgtgaag 31621 ctggaatcgc tagtaatcgc ggatcagcat gccgcggtga atacgttccc gggccttgta 31681 cacaccgccc gtcacaccac gagagtttgt aacacccgaa gtcggtgagg taacctttta 31741 ggagccagcc gccgaaggtg ggacagatga ttggggtgaa gtcgtaacaa ggtagccgta 31801 tcggaaggtg cggctggatc acctcctttc taaggatatt ttacggaata taagaccttg 31861 ggtcttataa acagaacgtt ccctgtcttg tttagttttg aaggaacttt gttccttgaa 31921 taagttaaga tgggcctgta gctcagctgg ttagagcgca cgcctgataa gcgtgaggtc 31981 ggtggttcga gtccactcag gcccaccatc ttatataacg gggccttagc tcagctggga 32041 gagcgcctgc tttgcacgca ggaggtcagc ggttcgatcc cgctaggctc caccaacgtg 32101 ttctttgaaa actagataac agtagacatc acattcaatt agtaacacaa gatatcacat 32161 agtgattctt tttaacggtt aagttagaaa gggcgcacgg tggatgcctt ggcactagga 32221 gccgatgaag gacgggacga acaccgatat gcttcgggga gctgtaagca agctttgatc 32281 cggagatttc cgaatgggga aacccaccac tcgtaatgga gtggtatcca tatctgaatt 32341 cataggatat gagaaggcag acccggggaa ctgaaacatc taagtacccg gaggaagaga 32401 aagcaaatgc gattccctga gtagcggcga gcgaaacggg attagcccaa accaagaggc 32461 ttgcctcttg gggttgtagg acactctgta cggagttaca aaggaacgag gtagatgaag 32521 aggtctggaa aggcccgcca taggaggtaa cagccctgta gtcaaaactt cgttctctcc 32581 tgagtggatc ctgagtacgg cggaacacgt gaaattccgt cggaatccgg gaggaccatc 32641 tcccaaggct aaatactccc tagtgaccga tagtgaacca gtaccgtgag ggaaaggtga 32701 aaagcacccc ggaaggggag tgaaagagat cctgaaaccg tgtgcctaca agtagtcaga 32761 gcccgttaac gggtgatggc gtgccttttg tagaatgaac cggcgagtta cgatcccgtg 32821 caaggttaag cagaagatgc ggagccgcag cgaaagcgag tctgaatagg gcgcatgagt 32881 acgtggtcgt agacccgaaa ccaggtgatc tacccatgtc cagggtgaag ttcaggtaac 32941 actgaatgga ggcccgaacc cacgcacgtt gaaaagtgcg gggatgaggt gtgggtaggg 33001 gtgaaatgcc aatcgaacct ggagatagct ggttctctcc gaaatagctt tagggctagc 33061 ctcaaggtaa gagtcttgga ggtagagcac tgattggact aggggcccct accgggttac 33121 cgaattcagt caaactccga atgccaatga cttatccttg ggagtcagac tgcgagtgat 33181 aagatccgta gtcgaaaggg aaacagccca gaccgccagc taaggtccca aagtatacgt 33241 taagtggaaa aggatgtgga gttgcttaga caaccaggat gttggcttag aagcagccac 33301 catttaaaga gtgcgtaata gctcactggt cgagtgactc tgcgccgaaa atgtaccggg 33361 gctaaacgta tcaccgaagc tgcggactgt tcttcgaaca gtggtaggag agcgttctaa 33421 gggctgtgaa gccagaccgg aaggactggt ggagcgctta gaagtgagaa tgccggtatg 33481 agtagcgaaa gaggggtgag aatcccctcc accgaatgcc taaggtttcc tgaggaaggc 33541 tcgtccgctc agggttagtc gggacctaag ccgaggccga aaggcgtagg cgatggacaa 33601 caggttgata ttcctgtacc acctcctcac catttgagca atggggggac gcaggaggat 33661 agggtaagcg cggtattgga tatccgcgtc caagcagtta ggctgggaaa taggcaaatc 33721 cgtttcccat aaggctgagc tgtgatggcg agcgaaatat agtagcgaag ttcctgattc 33781 cacactgcca agaaaagcct ctagcgaggt gagaggtgcc cgtaccgcaa accgacacag 33841 gtaggcgagg agagaatcct aaggtgatcg agagaactct cgttaaggaa ctcggcaaaa 33901 tgaccccgta acttcgggag aaggggtgct ctgttagggt gcaagcccga gagagccgca 33961 gtgaataggc ccaggcgact gtttagcaaa aacacaggtc tctgcgaagc cgtaaggcga 34021 agtatagggg ctgacgcctg cccggtgctg gaaggttaag aggagcgctt agcgtaagcg 34081 aaggtgcgaa ttgaagcccc agtaaacggc ggccgtaact ataacggtcc taaggtagcg 34141 aaattccttg tcgggtaagt tccgacccgc acgaaaggcg caacgatctg ggcactgtct 34201 caacgagaga ctcggtgaaa ttatagtacc tgtgaagatg caggttaccc gcgacaggac 34261 ggaaagaccc cgtggagctt tactgcagcc tgatattgaa tgttggtaca gcttgtacag 34321 gataggtagg agccttggaa accggagcgc cagcttcggt ggaggcatcg gtgggatact 34381 accctggctg tattgacctt ctaacccgcc gcccttatcg ggcggggaga cagtgtcagg 34441 tgggcagttt gactggggcg gtcgcctcct aaaaggtaac ggaggcgccc aaaggttccc 34501 tcagaatggt tggaaatcat tcgcagagtg taaaggcaca agggagcttg actgcgagac 34561 ctacaagtcg agcagggacg aaagtcgggc ttagtgatcc ggtggttccg catggaaggg 34621 ccatcgctca acggataaaa gctaccccgg ggataacagg cttatctccc ccaagagtcc 34681 acatcgacgg ggaggtttgg cacctcgatg tcggctcatc gcatcctggg gctgtagtca 34741 gtcccaaggg ttgggctgtt cgcccattaa agcggtacgc gagctgggtt cagaacgtcg 34801 tgagacagtt cggtccctat ccgtcgcggg cgcaggaaat ttgagaggag ctgtccttag 34861 tacgagagga ccgggatgga cgcaccgctg gtgtaccagt tgttctgcca agggcatcgc 34921 tgggtagcta tgtgcggacg ggataagtgc tgaaagcatc taagcatgaa gcccccctca 34981 agatgagatt tcccattccg caaggaagta agatccctga aagatgatca ggttgatagg 35041 tctgaggtgg aagtgtggcg acacatggag ctgacagata ctaatcgatc gaggacttaa 35101 ccacattttg aatgatgtca cacctgttat ctagttttga gagaacacct ctctaaaggc 35161 ggaaggtaag gaaactccgc taagggctct cacatcctgt gagaaacgcc cagtaccttc 35221 atcctgaagg catttgtttg gtggcgatag cgaagaggtc acacccgttc ccataccgaa 35281 cacggaagtt aagctcttca gcgccgatgg tagtcggggg tttccccctg tgagagtagg 35341 acgccgccaa gcaagcttaa acccagctta atgagctggg ttttttgttt actcaagatc 35401 gagaaaatca aacaaataca aacaccgagg gcttatatag cccatatact gatttaaagt 35461 ttcaaaaagg tctaaatagt gtatacaata tccgttttaa ggggaggcta actgtacgga 35521 ggtggagaag atggacgaaa cagttaaact taatcataca tgtgtgattt gtgatcaaga 35581 gaagaataga ggcattcatc tttatacgaa attcatatgc ttagattgtg agagaaaagt 35641 aatttctaca tcaacttctg atcctgacta tgcgttttac gtaaaaaaac taaagagcat 35701 tcatacaccg ccattatatt catagacctg aaaaggtctt tttttgtact cttaataata 35761 aaaagaagat gaaacttgtt taaggattga acgtagtaga taataatatt aaaactgagt 35821 atagacacag gagtcgatta tctcatgcag agattttttc actttttggt gtggagttta 35881 actagcagtg cgacttttgt tttcattgga atattgagct tttttggttt aaaccagtcg 35941 atttttttat ctattgttta tgggcttgct tctggagcag ccgtatatat agctggcatc 36001 tggaatgcaa gacggttatt tcttaaaaag catgaattga caggaagaga gtatgcttac 36061 attaagaaaa acttagagga agcaaggcag aaaatggtcc gtcttaggaa agccttgttt 36121 caggctaaaa gcattcaaat gtttaagcaa aatgcagaaa tgctaaggat tgtgagaagg 36181 atttatctcc tcaccaaaaa agagccaaag cggttttatc aggcagaacg atttttttat 36241 caaactctcg attcggttgt tgaattgaca gagaagtatg cttttctatc atctcaccca 36301 aaaaaaagca aagaactgtc gatgtcgtta agtgagacac gcatcactct tactgaattg 36361 accaagcgtt tagaggaaga tttaactcaa gcaatgggtg atgaaattga cgagttgcag 36421 tttgaattag acgcagcaaa acattcatta aagaaataag ggaagagggt aagagcgatg 36481 aaccgagacc aaagcgacct tcatatagat gaattattgg cagatccttt tggtggtaac 36541 atagagatac caggttcgga ggctgtaaaa gcagagaaag agcaagtacg gcttgttgat 36601 gttcttcctg aggaaaacaa ggaaaaagca attcagcttg ctggacagat tgatcataaa 36661 aatatgcaaa gcattgtctt atacggttca caagctcaat ctaaactgct gaacttttct 36721 catgatatga ttaatcatgt tcaaaagaag gatgtcgggg agattggcga aatacttgga 36781 gagctgatga aaaagctgga gcaagtaaat cctgatgatc tccaatctaa gaaaaagggt 36841 tttttggcac gcatgtttgg aagagtatca agttctcttc aagaggtgct gtctaaatac 36901 caaaagacca gtgtgcagat agacagaatc agcttgaagc tggagcactc taaaaatgct 36961 ttaatcagtg acaacaagct gttagagcag ttatatgaaa aaaataaaga atatttcgca 37021 gcgctgaatg tttatattgc tgcaggagaa ctgaagctgg aggaattaaa aacaaaaacg 37081 attcctgaac tgaagcaaca ggctgaatcg agtgatcata accaaatggc cgttcaagag 37141 gtgaatgatt taattcaatt tgctgaccgg ttagataaaa gggtgcatga tttgctgctg 37201 agcaggcaaa ttacaatcca aagtgcaccg caaatcaggc tgattcaaaa tacaaaccaa 37261 gcgttagctg aaaagattca gtcatccatt gtgacagcga ttccgttatg gaaaaatcaa 37321 gttgccattg cactgacgct tttaaggcag cgcaatgcag tggatgcaca gcagaaagta 37381 tctgatacaa ccaatgagct tttgctgaaa aatgcggagc ttttaaaaac caatacaatt 37441 gaaactgcac gggcaaatga aagaggcctt gttgatatag ataccttgaa gaaggtgcag 37501 gaaagcttaa taagcacgct tgaagaaaca ctgactatac aagaagaagg acgaatcaaa 37561 cgccgtcagg cagaagaaga gctcatgatg atggaaggcg acctgaagca aaagctgatt 37621 acaataaagg aaagatgatt accagtaagt ctggctttaa gttctgtcag aggcacgata 37681 taataaggtg taagaagaca cattcaaagg attgttttca tgaacacacc tttatataaa 37741 gcattaattc aacatgcgag aagaaattct cattcatttc atgttccggg acatcacaat 37801 ggagatgtct tttttgatga cgctaagtca atattcgatc cgcttctcac cattgatgta 37861 actgaactgg caggactgga tgatctccat catccttctg gggtgattaa ggaagctcag 37921 gagcttgcca gtcaattata tggatcggcg gaaagttttt ttctggtaaa tggtacgact 37981 gtcggaaact tagcgatgat tttatctgtt tgtgaacctg gtgatacaat tctggttcaa 38041 agaaactgtc ataaatctgt atttcatgct gttgatttgt ccggtgctga gccggtttat 38101 cttgcacctg acgttgattc agcgatgcat gtgcctacgc atgttccgct tggaacaatt 38161 aaagaggccc tggaagcata tccagatgcg aaaggcttgg tactgaccaa tccgacatat 38221 tacggacata gtgctgattt gactgagatc attactgaag cccatcatta cgggattcct 38281 gttttggtcg atgaagcgca tggcgcacat tttattttag gtgagccttt tccggtctca 38341 gctttaaaaa tgggggcaga tattgttgtt cagtcggccc acaaaacgtt gccagccatg 38401 acgatgggtt cttatttgca tctcaacagc agctgcagga ttaacaggga tcgggtggca 38461 gagtatttaa accgattaca aagcagcagc ccgtcttatc cgattatggc ttcgttagat 38521 attgcccgcg cttatgtaca gcatattata gaagaacaaa agctttctga cattctgcag 38581 cggatagaaa cacttaaaca aacgtttgat tcacttacaa atgcagaagc tgttaaccct 38641 gctaatccac tgatcatcac ggatccgcta aagctcacaa ttcgttcaaa acgcgggcat 38701 tctggctata cgctgcaaag cattttagag cgtgccaaca tattcactga gcttgctgat 38761 gaaaatcaag ttctgctcgt tctcccattg ggaggaaaac ggagaataaa cgctgaaatc 38821 attagaagca tcgatgaaga gattgagaaa acgcctccgg atcagacgtt tgtttctgca 38881 gaatggggtg tgcagcctgt tactgtcttg ccttatccaa aaaaggtctt acattcgttt 38941 aagaaagaat atgtgagctt tgaggaagca gctggccggc ttaatgcaga agatatcatc 39001 ccttatcctc cgggtatccc gatgattatg gcgggagaaa gaataacaaa agaaagtgtg 39061 caaaagctca gccgcttgat cagcatgaaa acgcatgttc aagggaatat gaaaatcaaa 39121 gagaaacaac tacttgttta tatagaagag gagaaatcat gagcggttta tttattacat 39181 tcgaaggtcc tgaaggtgca gggaaaacga ctgttctgca ggagatcaaa aacatactga 39241 cagcagaagg ccttcaggtt atggcaactc gagagccagg cggaatagat attgcagaac 39301 aaattagaga ggttattctg aatgagaaca atatattaat ggacccaaaa acagaagctc 39361 tcttatatgc ggctgcaaga cgccagcatt tagttgaaaa agtaaaacct gctttagaac 39421 aggggtttat cgttctttgc gacagattca tagacagttc tcttgcgtat caaggatatg 39481 caagagggct tggaattgat gaggttctgt ccattaatga atttgccatt ggagatatga 39541 tgccccatgt aacggtttat ttttcaattg atccggaaga aggactgaag cgtatttacg 39601 caaacggctc acgggagaaa aacaggctcg atttagaaaa actggacttt catacaaaag 39661 tacaagaagg ttatcaagag ctgatgaagc gatttccgga aagatttcat tcagttgatg 39721 ccgggcaatc caaagacctc gtcgttcagg atgttctaaa ggtgatcgat gaagcgttga 39781 aaaaaattca attgtgacct gtttcccaat agttgatata ataatgtaaa cgagatcacg 39841 ttgtttccaa tctaaaggag gccttcacag atgaaattga tagtggcagt tgtacaagat 39901 caggacagca acagactttt gaaaacctta acggatcaca acttcagagt cacaaagctt 39961 gcaacgacag gaggatttct taaatcaggc aatacaacgt ttatgatcgg tgtcgaggat 40021 atacgcgtca ataaagcgtt gagtctcatt aaagaaaacg ggcagaaacg tgatcagatg 40081 attgcccctg tatctccaat gggtggaaat gctgattcct atgtccctta tccagtcgaa 40141 gttgaagttg gcggagcgac agtatttgtc cttccagtcg atgaatttca tcaattttaa 40201 ggatctgaaa ctgtgaaaat taataaagat atacgtacat ttatagataa taagcagatt 40261 ccctctgtga aaacatctga gatcacagca tcgtttaaaa catcaatgga aaaccaaagc 40321 agcaaaatga agcttgatca gcttaccagg ctgttatctg atatagaagc atttggaaaa 40381 aggctaacga aatctcggaa ttttaaagac ttagcgagat ttaaaggact tgtgaaacgt 40441 tttgtcaaag aagctgtgga cagcggtctt tcacatgaaa catcgaaaag ctttgacctt 40501 tacgggaaca gcagaacgct gggacttgtg aaagaaatag atgacaaatt gatacagctt 40561 acggaagaga tgatggatca ggaaaaaccg gcaattgatt tgctggagcg tattggcgaa 40621 ataaaaggtt tattaattaa cctttacaca tagagagtga tacaatggca atatcctgga 40681 aggaaatgaa cgagcttcag cccagagtga tgaagctttt atataatagt attgagaagg 40741 acagactatc acacgcttat ttgtttgagg ggaaaaaagg aacaggcaag cttgatgccg 40801 cgctgcttct tgcaaaaagc ttcttttgtc tggagggtgg cgcggagcct tgtgagagct 40861 gccgaaactg taaacggata gagtcaggga accatcctga tctccatctt gttcagcctg 40921 atggcttatc aatcaaaaag gcgcaaattc aagcgctcca agaagagttt tctaagacag 40981 gacttgaatc gcataaaaag ctgtatatta tttcgcacgc agatcaaatg acagcaaatg 41041 cggcgaacag cctgctgaaa tttttagaag aaccgaacaa agacacaatg gccgtcctca 41101 tcactgagca gccccaaagg ttattggata ccatcatttc aagatgccaa acccttcctt 41161 ttcagccttt gcagccgaaa gcaattgaag acagactgat cgaacaggac gtctcgcctc 41221 atatggcaag gcttctggcc aacatgacta ataatgtagc agaagcagtc gaattaagtc 41281 gaaatgatga gtttgcagag tctagagcga aagtgataaa attgtatgaa gtcctacacc 41341 agcggaaagg acatgctttt ttctttattc aagatcaatg gatgcccttt ttcaaagaaa 41401 aaacccatca agaaatgggt cttgatatgc tcttattgat atatcgtgat gtgttgtcca 41461 tccaaatagg aaatgaagat aaattgattt atcaagactt attccaatca ataaaacagc 41521 atgcgctaca atcaacacaa caaagcgtta cgaatcagat acttgctgtt ttagaagcaa 41581 agaaacggct tcattccaat gtgaatgtac aaggattaat ggagcacttg gtgttaatgt 41641 tgcaggaggg ataagcttgt acaatgtaat tggtgtccgc tttaagaaag cgggtaaaat 41701 atattatttt gatccgaatg gatttcatat agaacatgac agctgcgtaa ttgtagaaac 41761 tgtcagaggc gttgagtacg gccaggtcgt aattgcaaat aaacaggtgg atgagcatga 41821 tgtggtgctt ccccttcgaa aagtgatacg tgtggcagac gatcgcgatc ttctcattgt 41881 agaagaaaat aaacaggaag cactatcagc atttgatatc tgccaaaaga aagtgattga 41941 gcatggcttg gatatgaagc tggtcgatgt tgaattcacg tttgatcgca ataaagtcat 42001 tttttacttc actgctgacg gccgagtcga ctttagagag cttgtaaagg atttggcttc 42061 tatctttaag acaagaattg agctgcgcca aatcggagtg agggatgagg caaaaatgct 42121 cggaggaatc ggtccttgcg gaagaatgct ttgctgttca acgtttcttg gagattttga 42181 acccgtttcc attaaaatgg ccaaggatca gaacttgtct ttaaatccta cgaagatttc 42241 gggtctttgc ggacgattga tgtgctgtct aaaatatgag aacgatgagt atgagacggc 42301 aaaagaacag cttccggata taggagaaat gattacgaca gcaaacggtc ccgcgaaggt 42361 cgtcggacta aatattctgg aacgggtgct tcaggtggaa ctgataaacc gtgaaaaagt 42421 gatagaatat acttgggaag agctcttgga agagggcgtc gtatccgcac aaaccacaga 42481 ttaacgaggt gtggaacctt ggataaaaaa gagttatttg atacagtcat taacttagaa 42541 gaacaaattg gctcactgta ccggcagctg ggggatttga agcagcatat cggtgagatg 42601 attgaggaaa atcatcattt acagcttgaa aacaagcatt tgcgcaaacg gctggacgat 42661 acgacgcagc agattgaaaa gttcaaagct gataaaaaag aatcaaaaac acagaagaca 42721 gagcaaactg atatagggga aggatatgat aatctggcac gtctgtatca agaaggattt 42781 catatctgca atgtccacta tggaagtgtt cgaaaagagg attgtctttt ctgtctgtca 42841 ttcttaaata aaaaataggg aaaaggcttc cgcataagac gggagccttt ttcaaaggta 42901 ctgaaaggat aagaagatgg tttcattaca tgatgatgaa agattagatt atttgctggc 42961 agaggacatg aaaatcatac aaagcccaac agtgtttgct ttttcgttgg acgctgtgct 43021 tctgtccaaa tttgcgtacg ttccgattca aaaagggaaa attgttgatt tatgcaccgg 43081 caatggtatt gtgccgctgc tgctcagtac aagatcaaaa gcagacattc tgggagtcga 43141 aattcaagaa agactgcatg atatggctgt tcgcagcgtg gagtataata agttggacga 43201 tcagatccag atcatacatg atgacctgaa aaacatgccg gagaaacttg gacataatcg 43261 atatgatgtt gtcacctgca atccgccgta ttttaaaacg ccgaaacaaa ctgaacaaaa 43321 catgaacgag catctccgaa tcgcaagaca tgaaatccac tgcacgctgg aggatgtcat 43381 ttcagtcagc agcaagctgc tcaagcaagg gggaaaagca gctcttgttc accggccggg 43441 aaggcttctg gagatttttg aactgatgaa ggcttatcaa atcgagccga aacgtgtaca 43501 atttgtctat ccgaagcaag ggaaagaagc caataccatt ttggttgaag gtatcaaagg 43561 cgggcgcccg gatttgaaaa ttcttcctcc cttattcgta tatgatgaac aaaatgaata 43621 tacaaaagaa atcaggacca ttttatatgg agacaaataa ccatttcttc tacgtcgtga 43681 aatgtaagga caatagctgg tatgccgggt ataccaacga tctgcataaa cgagtgaaaa 43741 cgcacaatga tggaaagggc gcaaagtaca caaaagtaag acgtccggtt gaattaattt 43801 ttgccgagag cttttcaaca aagcgggaag ctatgcaggc ggaatattat ttcaaaaaac 43861 taactcggaa gaaaaaagag ctttatatag aagaaaagcg gaacagcaag gaggctgtat 43921 atgttaaggc gccaaatgag ctttaatgga aagtcggaca tggggattct ttacttggtc 43981 ccaaccccaa tcggaaattt agaggatatg acattccggg cgatcgacac gctgaaatca 44041 gtggatgcga ttgctgcgga agatacgagg caaacgaaaa agctttgtca tgtatatgaa 44101 attgaaacac cgctcgtcag ctatcacgaa cacaataaag aaagcagtgg gcacaaaatt 44161 attgaatggc tgaaatcggg aaaaaacatt gctcttgtca gtgatgccgg tctgccgacg 44221 atttctgatc ccggagcgga aattgtaaag gattttacgg atataggcgg ttatgttgtt 44281 ccgttgccgg gagcaaatgc tgcattaaca gctcttattg cttcaggtat tgtaccgcag 44341 ccttttttct tttacggttt tctcaacaga cagaaaaaag aaaagaagaa ggagcttgaa 44401 gcccttaaaa aacggcagga aacgatcatt ttttatgaag cgccccacag attgaaggaa 44461 accttgtcag cgatggcaga gatattagga gatcgggaaa ttgctgtaac acgtgaactc 44521 actaagaaat atgaagagtt tatccgagga accatatctg aggtcattgg atgggcaaac 44581 gaggatcaga tacgcggcga gttttgtctt gtcgtagaag gaagtaataa tgaagaggta 44641 gatgaggaag aacaatggtg ggaaaccctc actgcgaaag aacatgtcga gcattacatt 44701 tcgaaaggcg ctacgtctaa agaagctatt aaaaaagcag cagtcgatcg caatgtacca 44761 aagcgtgaag tgtacgatgc ttaccatatt aagcaataaa aaaacgttct tgtgtcataa 44821 caagaacgtt ttttgtacaa gaaatgatta tttaaggttt tgaagctggt tttggatttc 44881 gctgatgatt tgctcagcgc cttctttact aagaaccaat ttaccgcctg caagtttaag 44941 gttatcatca gaaacttcac cagttacttg gcaagtcatg tttggtttat attttttaag 45001 gatgattttt tcatcatcaa catagatttc aagagcatct ttttctgcga ttccaagagt 45061 acgacgcagt tcgataggaa taactacacg tcctaattca tcaactttac gtacaatacc 45121 agtagatttc ataaacattc tcctcccaag agatacttat ttgtttaaat tatatttttc 45181 ttcgtcatta ttcgacaaaa tccttacctt catagcataa caaggtttcc aataatcgtc 45241 aatcattttg tttactattg attgtaagaa ttagttctta tagtcagtaa tgtcttggaa 45301 actaccgaaa taacagcatt ttataaatat ttaataaagc tattatccta ctaaaaatcc 45361 ttttaaatca agactttcga accaaagttt tttatttcat ttgattatat acgacaaaat 45421 tcgacacgaa cagacttttt ttattttcat taaagatttt taattttaat tattcttttt 45481 cagggcgtat gtatatattc ttgatcttaa aggctaagat ggtatcatag ataaaggata 45541 aatataaata atattcatat atgatttgca cttatcgccg ctctcgtcct ttgggcggga 45601 gctttttgac attctgatta ggaggtttca agatgccgca agaaaacaat acattttaca 45661 ttacaacacc gatttattat ccgagcggaa aattacatat cggccatgca tatacgacag 45721 tcgcaggaga tgcaatggca cgttacaaaa gattaaaagg gttcgatgtt cgctatttaa 45781 cgggaacgga cgagcatgga caaaagatcc agcaaaaagc tgaacaggaa aacattacac 45841 ctcaggagta tgtggatcgc gcagcggcag atattcaaaa actgtggaag cagcttgaaa 45901 tctcaaacga cgactttatc cgcacgacag aaaaacggca taaagttgtc attgaaaaag 45961 tgtttcaaaa gcttcttgat aacggggaca tctatcttga tgagtatgaa ggctggtaca 46021 gcatccctga tgaaacgttc tacacggaaa ctcagctcgt tgatattgag cggaatgaaa 46081 agggagaggt catcggcgga aaaagccctg acagcggtca cccagttgaa ttgatcaaag 46141 aggaatctta tttcttccgc atggggaaat acgcggatcg tcttctgaaa tactatgaag 46201 aaaacccgac attcattcag ccagaatcac gcaaaaacga aatgattaat aactttatca 46261 aacctggact tgaggatttg gcagtatcac gtaccacttt tgattggggc gtgaaggtgc 46321 cggaaaatcc aaagcatgtt gtatatgttt ggattgacgc actatttaac tatttaacgg 46381 cactcggtta tgatacagaa aatgatgagc tttatcaaaa atattggcct gccgatgttc 46441 atttagtcgg taaggagatt gtacgattcc atactattta ctggccaatt atgctgatgg 46501 cgctggatct tccgctgcca aagcaagtat tcgcgcatgg ctggcttttg atgaaagacg 46561 gaaaaatgtc gaaatcaaaa ggaaacgttg tagatccggt tacattaatt gaacgctatg 46621 gtttagacga acttcgctat tacttgcttc gcgaagtgcc gttcggatca gacggtgttt 46681 tcacgccgga aggatttgtt gagcgaatca actatgattt agcgaatgat ttaggaaatc 46741 tattgaatcg tactgttgcg atgattaata agtattttga cggacaaatc ggttcttaca 46801 aaggtgctgt tacggaattt gaccatacgc tcacttctgt tgctgaagaa acagtgaaag 46861 cttatgagaa agcaatggaa aatatggagt tctcggtagc actttcgact ttatggcagc 46921 tcatcagccg cacaaacaaa tacattgatg agacagctcc atgggtgctt gcgaaagatc 46981 cggcaaaaga agaagaattg cgatcagtta tgtatcatct cgctgaatca ttgcgtattt 47041 cagcggtact gcttcagcca ttcttaacaa aaacacctga aaaaatgttc gagcagctgg 47101 gcattactga tgaatcttta aaagcttggg acagcattac agctttcggc cagctgaaag 47161 atacaaaagt acaaaaaggc gagccattgt tccctcgttt agaggcagaa gaagaaattg 47221 cttacatcaa agggaaaatg caaggttcag caccagcgaa agaagaaaca aaagaagaag 47281 agcctcaaga ggtcgatcgt ttacctgaaa ttacgattga tcaatttatg gatgtagagc 47341 ttcgcgtagc tgaggtcatt gaggcagagc cagtgaaaaa agcagaccgt ttattgaagc 47401 tgcagcttga tcttggtttt gaaaagcgcc aagtggtatc cggcattgcg aagcattata 47461 cgcctgaaga gcttgttgga aaaaaactcg tttgtgtaac aaatctaaaa ccggttaaac 47521 tcagaggaga gctttctcaa ggtatgatcc ttgcaggaga agcagacggc gttttaaagg 47581 tcgtatctat cgatcagtcg ttaccaaaag gcacaagaat taaataatga taaacaaaag 47641 gtgtttcacg tgtaacaatt cgtcgaacac cttttgtgtt tcgacaagaa aggagttttt 47701 cacttatgtt gtttgacact cacgcgcatt taaatgcaga acaatatgat actgatcttg 47761 aagaggttat tgaacgggca aaagctgaaa aagttgaacg aattgtcgta gttggttttg 47821 accgtccgac gattacccgt gcgatggaaa tgattgagga atatgatttt atttatgcag 47881 ccattggctg gcaccctgtt gacgctattg acatgacaga ggaagactta gcgtggatta 47941 aagagctttc tgctcatgag aaagtggtag cgatagggga aatgggactg gattatcatt 48001 gggataaatc acctaaagat attcaaaaag aggtgtttag aaatcaaatc gccttagcga 48061 aagaggtcaa tttgcctatt atcattcata accgtgatgc aacggaggat gtcgtgacca 48121 ttttgaaaga ggaaggcgca gaagctgtgg gcggaatcat gcactgcttt acaggaagtg 48181 cggaagtggc aagagaatgc atgaaaatga atttttattt atcatttggg ggaccggtga 48241 catttaaaaa tgcgaagaaa ccgaaggaag tagtgaagga aattcccaat gaccggctgc 48301 tgattgaaac ggactgcccg tttctcacac cgcacccttt ccgcgggaaa agaaatgagc 48361 caagctatgt gaaatatgtg gcagaacaaa tcgccgaatt aaaagaaatg acctttgaag 48421 agattgcttc catcacgact gaaaatgcga aaagactttt ccgtataaac tgacaaaaaa 48481 cgctagcggg ttttgtaaga gcttgtccct tacagcgttt ttctataaaa gttctacatg 48541 ctttcttctc ctcataggat aggtttgtcg acaagtcttt cttccgtttc tcagtgtatt 48601 tcaggataat gaagaggaca ctgagctttt gggagaaaga gaagggaggg ttgacagcct 48661 tttagatact ctatataatc tctccgagga gaaggaggcg tttttcatca cacaaaaaat 48721 gaaaaagctg ttttccgtaa agcttagcaa aagcaaagtc attctggttg ctgcttgttt 48781 gcttttggca ggaagcggga ctgcgtacgc ggctcatgag ctgacgaaac aatcagtctc 48841 agtttctatc aatggcaaaa agaaacatat acgcacacat gcaaatacag tcggtgatct 48901 tttggagacg cttgatataa agacaagaga cgaagacaag atcacacctg ctaaacagac 48961 aaagataaca gcagacatgg acgttgtgta tgaggctgca aaacctgtga agcttacaat 49021 aaacggggaa gaaaagacgt tatggtcaac agcaaaaacg gtcggtgcat tactggacga 49081 acaagatgtt gatgtgaaag aacaagatca aattgatccc gcaatagata cagatatttc 49141 gaaagacatg aagattaaca tagagcccgc atttcaggtt actgtgaatg atgcagggaa 49201 acaaaagaag atctggacga cttcgactac ggtcgctgac tttttaaaac agcaaaagat 49261 gaacataaaa gacgaagata aaatcaagcc tgcgttagat gcaaagctga cgaaaggaaa 49321 ggctgatatt acaattactc gtatcgaaaa ggtcaccgat gtagttgaag agaagattgc 49381 gttcgatgtg aaaaagcaag aagacgcttc tcttgaaaaa gggaaagaaa aggtcgtcca 49441 aaaaggaaaa gaaggcaagc taaaaaaaca tttcgaagtc gttaaagaaa acggtaaaga 49501 agtgtccaga gagcttgtaa aagaagaaac agctgaacaa agcaaagata aagtgattgc 49561 tgtcggcaca aagcaaagca gtccaaaatt tgaaacggtc agtgcttcag gtgattcaaa 49621 aacagttgtg tcccgcagca atgaatcaac aggcaaagtc atgactgtat catctacggc 49681 ttatacggca agctgcagcg gttgttcagg acatacagcg acaggcgtca atttaaaaaa 49741 taatccgaat gccaaagtca tcgctgtgga tccaaatgtc attccgctag gctccaaagt 49801 ccacgtggaa ggctatggat atgccattgc tgcagatacc ggttcagcga ttaaagggaa 49861 caagatagac gtctttttcc cagagaaatc atcggcgtac cgatggggaa ataaaacagt 49921 caaaattaaa atcttaaatt agtatatact tatgtattca gagggttttg cgccctctgt 49981 ttttttcgtt ataatagaca aagtgcattt tctgcttatt agacgctcga tataagaaaa 50041 agtttcatga atatacaaaa gtttttattt tgtcttggag gaaataatga aaattaaaga 50101 gatcattgtg gtcgaggggc gtgacgatac ggcccgcatc aaattggctg ttgatgcaga 50161 cacaattgaa acaaatggtt cagccatcga tgatcatgtg attgaccaaa tccgtttggc 50221 ccagaagacg agaggcgtca ttattttaac ggatccggac tttccgggag agaagattcg 50281 caaaaccatc tcagaggctg tacccggctg taagcatgca tttttgccaa aacatcttgc 50341 caaacctaaa aacaagcggg gaattggtgt ggagcatgca tcggttgaaa gcattagggc 50401 atgtttagaa aatgtgcatg aggagatgga agcgcagccg agtgacattt cagctgagga 50461 tttgattcat gccggactaa taggcgggcc tgcggccaaa tgccgccggg aacgactggg 50521 tgatctgttg aaaatcggct atacaaatgg caaacagctt caaaaacggc tgcaaatgtt 50581 tcaaattaaa aaaagtgatt ttatgagtgc gctcgatacc gttatgcggg aggaacagaa 50641 tgaataaaga tattgcgaca ccgattagaa cgaaagagat actgaagaaa tacggttttt 50701 cttttaaaaa gagcttagga cagaatttct taattgatac gaacatttta aacagaattg 50761 ttgatcacgc ggaagtgacg gagaaaacag gtgtcattga aatcggcccg ggaatcgggg 50821 ctttaaccga acagcttgcc aagcgggcga aaaaggtcgt ggcatttgag attgaccagc 50881 gattattgcc gattctgaag gatacactgt caccttacga aaatgtcact gtcattcatc 50941 aggacgtgtt aaaggctgat gtcaaatcag tcattgaaga acaatttcaa gattgtgatg 51001 agatcatggt agttgccaac cttccttatt acgtaacaac accgattatc atgaaactgc 51061 ttgaagaaca tcttccgctg aaagggattg tggttatgct gcaaaaagaa gtggctgagc 51121 gcatggcggc tgatccttca tctaaggaat acggctcgct ttcaatcgcg gtgcagtttt 51181 atacagaagc caaaacggtg atgatcgtcc cgaaaaccgt atttgttcct cagcctaatg 51241 tcgattccgc agtcattcgt ctgattctcc gagacggccc ggcagtggac gtggaaaacg 51301 aatccttttt ctttcagctc atcaaggcaa gctttgcaca gcgccgtaaa acgctgctca 51361 ataacttagt taacaatctg cctgaaggaa aagcacaaaa atcaacgatt gaacaagtgc 51421 tcgaagaaac aaatattgac ggtaagcgcc gaggtgaatc cctgtctatt gaggaattcg 51481 cagcgctgtc taacggattg tataaagccc ttttctaaaa gggctttttg ttttgcgcac 51541 cacatggact gccgctacat aggctagaga aggacctttc attcaatgat aagaaaaaac 51601 ttggactcag cgaaaaaagg cgctttctca aggctctttc tttcatgatg aggcttagtc 51661 tatgtgtgga gtgaggaacg tgcaatttca aataggggat atggtagcca gaaaatccta 51721 tcagatggat gttttgtttc gaattatagg aatagagcaa acaagcaaag gaaattcaat 51781 tgccattttg catggagatg aagtcaggct gattgctgat tcggattttt ctgatctggt 51841 ggcagtgaaa aaggatgagc agatgatgcg gaaaaagaaa gatgagagca gaatgaatga 51901 gtcgctcgaa ttgctccgcc aagattataa gctgctcaga gaaaagcagg agtactatgc 51961 gacaagccaa tatcagcatc aggagcatta tttccatatg ccgggcaaag tgcttcatct 52021 ggatggtgac gaagcatatt tgaaaaaatg cctgaatgtc tataaaaaaa ttggagtgcc 52081 ggtctatggc atccattgcc atgaaaagaa aatgtctgct tctattgaag tattgctcga 52141 caaatatcga cctgacatcc tggtgatcac agggcatgat gcgtactcga agcaaaaggg 52201 cggtattgat gatttgaatg cgtacagaca ttctaagcac tttgttgaaa cagttcaaac 52261 agcccgaaaa aagatccctc acttagatca gcttgttatt tttgcggggg cctgccaatc 52321 ccattttgaa tcactcatca gagcgggtgc gaattttgca agttcaccgt caagagtcaa 52381 tattcatgcg cttgatccgg tatatatcgt cgcgaagatc agctttacgc cgtttatgga 52441 acggattaat gtatgggaag tgctccgtaa tacgctgaca agagagaaag ggcttggagg 52501 tattgaaaca agaggagttc tgagaattgg tatgccttat aagtccaatt aacagttgaa 52561 aacctgcata ggagagctat gcgggttttt tattttacat aatgatacat aatttaccga 52621 aacttgcgga acataattga ggaatcatag aattttgtca aaataatttt attgacaacg 52681 tcttattaac gttgatataa tttaaatttt atttgacaaa aatgggctcg tgttgtacaa 52741 taaatgtagt gaggtggatg caatggcgaa gacgttgtcc gatattaaaa gatcgcttga 52801 tgggaattta ggtaaaaggc tgacgttaaa agcaaacggt ggccgccgaa aaacgattga 52861 gcgttcgggc attttagctg agacgtaccc ttctgttttt gtgatacaac tagatcaaga 52921 cgagaactcg tttgaaagag tttcatacag ttatgctgat attttgactg agactgttga 52981 gctgacattt aatgatgacg ccgcaagctc agtggcattt taacgggcag tgaacctttt 53041 gtttactgct ttttgttttg cccttttttg gtttccaata attttaacga aagttccatc 53101 tgatttaaca aaagataaaa cagtcacata ttatcgtgac gtgcacgaat ggctatcact 53161 tctaaaaaag gagttgtttc gtttgggcag acgtcgtgga gttatgtcag atgagtttaa 53221 atatgagctg gctaaagacc ttggttttta tgacacagta aaaaatggag gctggggtga 53281 aattcgggcc cgcgatgccg gtaacatggt gaagcgtgct attgaaatcg ccgaacagca 53341 aatggctcag aatcagaata accgataagg atgtgacccg ggggacgtgc tgttccctgg 53401 tttttttatt ttggatataa atacataatg ggctgaatat ggatatgttc atcctgtact 53461 tcaaatgtga tacaatgttc atacttatgt ttagatggag aagtaggtga aagctatgcg 53521 tattttagaa aaagcgccag ctaagatcaa tctgtcactt gacgtcaccc gaaaacgccc 53581 ggatggctat catgaagtcg aaatgatcat gacgacaatt gatttagctg atcgaattga 53641 attgacggag cttgcagagg atgaagtgag ggtttcctcc cacaaccgat ttgtgcctga 53701 tgaccaaaga aacttagctt atcaggctgc caagctgatc aaggacagat acaacgtgaa 53761 aaagggagtt tccatcatga ttacgaaggt aattccggtg gctgccggtc ttgccggcgg 53821 aagcagtgat gcggcggcga cactcagagg gctgaacaga ctgtggaatt taaatctgtc 53881 cgcggaaacg cttgctgagc ttggagcgga aattggctct gacgtttcat tttgtgtcta 53941 tggcggaact gcattagcaa cagggcgcgg cgagaaaatt aaacatatca gcacgcctcc 54001 gcactgctgg gtcattttag cgaagccgac aatcggtgtt tcaactgctg aagtgtacag 54061 agcgctgaaa ctggatggta tagagcatcc cgatgtacaa ggcatgatcg aggcgataga 54121 agaaaagagt tttcagaaga tgtgcagccg gttaggcaat gtgcttgaat ctgttacact 54181 cgatatgcat cctgaagttg cgatgatcaa aaaccagatg aaacgctttg gtgcagatgc 54241 cgtgttaatg agcgggagcg gcccgacagt gtttggactg gttcagtatg agtcgaaggt 54301 gcagagaatt tataacgggt taagaggctt ctgcgatcaa gtttatgcgg tgagaatgat 54361 cggcgaacag aacgctcttg attaaatccg tatgttaagt tatattgatc ttaaaatatt 54421 cggattttgg gggtgagttc atgaagtttc gtcgcagcgg cagattggtg gacttaacaa 54481 attatttgtt aacccatccg cacgagttaa taccgctaac ctttttctct gagcggtatg 54541 aatctgcaaa atcatcgatc agtgaagatt taacaattat taaacaaacc tttgaacagc 54601 aggggattgg tactttgctt actgttcccg gagctgccgg aggcgttaaa tatattccga 54661 aaatgaagca ggctgaagct gaagagtttg tgcagacact tggacagtcg ctggcaaatc 54721 ctgagcgtat ccttccgggc ggttatgtat atttaacgga tatcttagga aagccatctg 54781 tactctccaa ggtagggaag ctgtttgctt ccgtgtttgc agagcgcgaa attgatgttg 54841 tcatgaccgt tgccacgaaa ggcatccctc ttgcgtacgc agctgcaagc tatttgaatg 54901 tgcctgttgt gatcgttcgt aaagacaata aggtaacaga gggctccaca gtcagcatta 54961 attacgtttc aggctcctca aaccgcattc aaacaatgtc acttgcgaaa agaagcatga 55021 aaacgggttc aaacgtactc attattgatg actttatgaa agcaggcggc accattaatg 55081 gtatgattaa cctgttggat gagtttaacg caaatgtggc gggaatcggc gtcttagttg 55141 aagccgaagg agtagatgaa cgtcttgttg acgaatatat gtcacttctt actctttcaa 55201 ccatcaacat gaaagagaag tccattgaaa ttcagaatgg caattttctg cgttttttta 55261 aagacaatct tttaaagaat ggagagacag aatcatgaca aaagcagtcc acacaaaaca 55321 tgccccagcg gcaatcgggc cttattcaca agggattatc gtcaacaata tgttttacag 55381 ctcaggccaa atccctttga ctccttcagg cgaaatggtg aatggcgata ttaaggagca 55441 gactcatcaa gtattcagca atttaaaggc ggttctggaa gaagcgggtg cttcttttga 55501 aacagttgta aaagcaactg tatttatcgc ggatatggaa cagtttgcgg aagtaaacga 55561 agtgtacgga caatattttg acactcacaa accggcgaga tcttgtgttg aagtcgcgag 55621 actcccgaag gatgcgttag tcgagatcga agttattgca ctggtgaaat aataagaaaa 55681 gtgattctgg gagagccggg atcacttttt tatttacctt atgcccgaaa tgaaagcttt 55741 atgacctaat tgtgtaacta tatcctattt tttcaaaaaa tattttaaaa acgagcagga 55801 tttcagaaaa aatcgtggaa ttgatacact aatgctttta tatagggaaa aggtggtgaa 55861 ctactgtgga agttactgac gtaagattac gccgcgtgaa taccgatggt cgcatgagag 55921 cgattgcatc catcacgctg gatcacgaat ttgttgtaca tgatattcgt gtgattgatg 55981 gaaacaatgg tcttttcgtt gcgatgccga gtaaacgcac ccctgatgga gagttccgcg 56041 atattactca tcctattaat tcaagcacgc gaggaaagat tcaagatgcc gtgttaaatg 56101 agtatcatcg tctgggtgac actgaagcat tagaattcga agaagctgga gcttcttaaa 56161 aaataaccaa aaagcaagga ctgctgaaag ggctgacata agccttttgc cggcggtcct 56221 tttttaattc tgatttttca aacttagttg cactcaatag aaaattcttg cacttcatga 56281 agtctccttg aaatcagaag atatttagga tatatttttc tatggataaa agggatattg 56341 gaggccaata aatggataag cggtttgcag ttgttttagc ggctggacaa ggaacgagaa 56401 tgaaatcgaa gctttataaa gtccttcatc cagtttgcgg taagcctatg gtagagcacg 56461 tcgtggacga agccttaaaa ttatctttat caaagcttgt cacgattgtc ggacatggtg 56521 cggaagaagt gaaaaagcag cttggtgata aaagcgagta cgcgcttcaa gcaaaacagc 56581 ttggcactgc tcatgctgta aaacaggcac agccatttct tgctgacgaa aaaggcgtca 56641 caattgtcat ttgcggagat acgccgcttt tgacagcaga gacgatggaa cagatgctga 56701 aagaacatac acaaagagaa gcgaaagcta cgattttaac tgcggttgca gaagatccaa 56761 ctggatacgg ccgcattatt cgcagcgaaa acggagcggt tcaaaaaata gttgagcata 56821 aggacgcctc tgaagaagaa cgtcttgtaa ctgagatcaa caccggtacg tattgttttg 56881 acaatgaagc gctatttcgg gctattgatc aggtgtctaa tgataatgca caaggcgagt 56941 attatttgcc ggatgtcata gagattctta aaaatgaagg cgaaactgtt gccgcttacc 57001 agactggtaa tttccaagaa acgctcggag ttaatgatag agttgctctt tctcaggcag 57061 aacaatttat gaaagagcgc attaataaac ggcatatgca aaatggcgtg acgttgattg 57121 acccgatgaa tacgtatatt tctcctgacg ctgttatcgg aagcgatact gtgatttacc 57181 ctggaactgt gattaaaggt gaggtgcaaa tcggagaaga tacgattatt ggccctcata 57241 cggagattat gaatagtgcc attggcagcc gtacggttat taaacaatcg gtagtcaatc 57301 acagtaaagt ggggaatgat gtaaacatag gaccttttgc tcacatcaga cctgattctg 57361 tcatcgggaa tgaagtgaag atcgggaatt ttgtagaaat taaaaagact caattcggag 57421 accgaagcaa ggcatctcat ctaagctatg tcggcgatgc tgaggtaggc actgatgtaa 57481 acctgggctg cggttcaatt actgtcaatt atgatggaaa gaataagtat ttgacaaaaa 57541 ttgaagatgg cgcgtttatc ggctgcaatt ccaacttggt tgcccctgtc acagtcggag 57601 aaggcgctta tgtggcggca ggttcaactg ttacggaaga tgtacctgga aaagcacttg 57661 ctattgccag agcgagacaa gtaaataaag acgattatgt gaaaaatatt cataaaaaat 57721 aatcctaaat tcggaggttt atccatgtct aatcaatacg gagataagaa tttaaagatt 57781 ttttctttga attcgaatcc agagcttgca aaagaaatcg cagatatagt tggagttcaa 57841 ttagggaaat gttctgtcac aagatttagt gacggggaag tccaaattaa tatcgaagaa 57901 agtattcgcg gatgtgattg ttacatcatc cagtctacaa gtgaccccgt taacgagcat 57961 attatggaac tgctgattat ggtagatgcg ttaaaacgcg cttctgcaaa aacgattaac 58021 attgttattc cttattacgg ttatgcgcgt caagacagaa aagcaagatc ccgtgagcca 58081 atcacagcta aacttttcgc taacctgctt gaaacagccg gtgcgactcg tgtgattgca 58141 cttgacctgc atgcgccgca aattcaagga ttctttgata taccgattga ccacttaatg 58201 ggtgttccga ttttaggaga atattttgaa ggcaaaaatc ttgaagatat cgtcattgtt 58261 tcaccagacc atggcggtgt gacacgtgcc cgcaaactgg ctgaccgact aaaagcgcca 58321 attgcgatta tcgataaacg ccgtccgcgt ccaaacgtgg cggaagtcat gaatattgta 58381 ggtaacatcg aagggaagac tgctatcctc atcgatgaca ttattgatac tgcaggtacg 58441 attacacttg ctgctaatgc gctcgttgaa aacggagcga aagaagtata tgcatgctgt 58501 acacaccctg tactatcagg ccctgcggtt gaacggatta ataattcaac aattaaagag 58561 cttgttgtga caaacagcat caagcttcct gaagaaaaga aaattgaacg ctttaagcag 58621 ctttcagtcg gaccgcttct ggccgaagcg attattcgcg ttcatgagca gcaatcagtc 58681 agctatctgt tcagctaaac catttttcga ggtttaaatc cttatcgtta tgggtattgt 58741 ttgtaatagg acaactaaaa cgacaagagg atggtgctga atatggcaac tttaacggca 58801 aaagaaagaa cggactttac tcgttcgtct cttcggaata tccgtacttc aggacatgtt 58861 ccaggtatca tatatgggaa ggatacgggt aacaaacctg tgtcattaga cagtgtggag 58921 ctcatcaaaa cgctgaggga cgaaggcaaa aatgcagtca ttacgcttga ggtcagcgga 58981 gaaaaacact cagtcatggt aacagacctg cagacggacc cgctgaaaaa tgaaatcact 59041 catgctgatt ttcaagtagt taatatgagt gaggacattg aagtggaagt tccgattcat 59101 ctgaccggag aagccattgg agtgaaaaac ggaggcgtac tgcagcagcc gttatatgca 59161 cttactgtaa aggccaagcc aaaagccatt ccgcaaacga ttgaggctga tatttcaagc 59221 ctcgatgtaa atgaagtact gacgattgcg gatttgcctg ctggcggtga ctactccttt 59281 aatcatgaat cagatgaggt tgtggcttca atccttcctc cgcagcagca ggaagcagct 59341 gaggtcgatg aagaggaatc tgccgatgct cagcctgaag gtgaaaacga acaataatag 59401 cttaaggcgt aaccctcccg cggttacgtc ttttgtgcta gaatgagaag aattatagcc 59461 cgtttatgaa gacgggagtt atgtgactaa gggaggattc gccatgcttg tgattgccgg 59521 tctcggaaac ccggggaaga actatgaaaa tacacggcat aatgtcggat ttatggtgat 59581 agatcagctt gcaaaggaat ggaatataga gctgaatcaa aataaattta acggattata 59641 cggaaccgga tttgtttccg gcaaaaaggt tctacttgtt aaaccgctta catatatgaa 59701 tttatcagga gaatgtttgc ggcctttaat ggactactat gatgtcgata acgaagattt 59761 gacagtcatt tacgacgacc ttgaccttcc gactggcaag atccgtttaa gaacgaaagg 59821 aagcgccgga gggcacaatg gcatcaaatc actgatccag catcttggaa cgtccgagtt 59881 tgaccgtatc cgcatcggaa tcggccggcc tgtaaacggc atgaaggtcg ttgattatgt 59941 gttaggctcc tttaccaagg aggaggcacc tgagatcgaa gaagcggttg ataaatctgt 60001 gaaggcttgt gaggcttctt tgagtaaacc gtttttagaa gtcatgaacg aatttaacgc 60061 aaaggtataa aatgtaacaa caaagtccat actacaccaa aatgactttt tcatcaggag 60121 gacccttgta tggctttgca ttattattgt cgtcattgcg gagtgaaagt aggcagtctc 60181 gaatcttcaa tggtatcgac agactcactt ggatttcagc acttaacaaa tgaggaaaga 60241 aacgatatga tttcttataa agaaaatgga gatgtccatg ttttgacgat atgtgaagac 60301 tgccaagagg cgcttgaccg aaatccgcat taccacgaat atcacacatt tattcaataa 60361 aaagctttgg tgtagacact agaccaaagc gtttttctgt tctcgcagga aacagagagg 60421 aggggccata tggacaacat tcaaaccttt ataaaagaaa gcgatgactt taaatccatc 60481 atcaacggtt tacacgaggg cctgaaggaa cagctgctcg cgggtctgtc gggttccgcg 60541 cgttctgttt ttacttctgc tctggctaat gaaacgaata agcctatctt tctcatcacc 60601 cataacttat atcaagccca gaaagtaaca gatgatctga cttcacttct agaggatcgg 60661 tctgtccttt tgtaccccgt caatgaactc atttcatcag aaatcgcagt tgcaagccct 60721 gaattgcggg cgcagcgatt agatgtcatt aatagactaa cgaatggaga agcgccaatt 60781 gtcgttgctc cggtagctgc aatcagaaga atgctgccgc ctgttgaggt gtggaaaagc 60841 agccagatgc tcattcaagt aggccatgat attgaacctg accagcttgc ctcacggctg 60901 gtagaggtag ggtatgagcg gtctgatatg gtttctgcgc ccggggaatt cagtattcgc 60961 gggggaatca ttgacattta tccgctgact tcagagaatc cggtgagaat tgaacttttt 61021 gacaccgagg tggattcaat ccgcagcttt aattcagatg atcagcggtc aattgagacc 61081 cttacctcga tcaatatcgg tcccgcgaag gaattaatta tcagaccgga agaaaaagcg 61141 cgggcgatgg agaaaatcga tagtggtctt gccgcgagct tgaaaaaatt aaaggctgac 61201 aaacaaaaag aaatacttca tgcgaatatt tctcacgata aagaacgctt gtctgaaggc 61261 cagacagatc aggagctcgt gaagtatctc tcatatttct atgaaaagcc tgctagttta 61321 ctagattata cacctgataa tacacttctg attttggatg aagtcagtcg gattcatgag 61381 atggaagaac agcttcaaaa agaagaagcg gagtttataa caaatcttct tgaggaaggg 61441 aagattttgc atgacattcg tttgtcattc agcttccaaa aaatagtggc tgagcaaaaa 61501 cggcctctgc tgtactactc tttatttttg cggcatgtac accatacgag cccgcaaaat 61561 atcgtcaatg tgtcaggccg gcaaatgcag agtttccatg gccaaatgaa cgtgcttgcg 61621 ggcgaaatgg agcgttttaa aaaatcaaat ttcactgttg tgttcttagg agcaaacaag 61681 gaacgtacgc agaaattgtc atctgttttg gctgattatg atatcgaggc cgccatgaca 61741 gacagcaaaa aagcgcttgt tcagggacag gtctatatca tggaaggcga gctccaatcg 61801 ggatttgagc tgccgttaat gaagcttgcc gttatcacgg aagaagaact gttcaaaaac 61861 cgtgtaaaga agaagccgcg aaaacagaag cttaccaatg cagagcgcat caaaagctat 61921 tctgagcttc aaattggaga ttatgtcgtt catattaatc acgggatcgg aaaatacctg 61981 gggattgaaa ctcttgaaat caacggcatt cataaagact atttaaatat acattatcag 62041 ggcagtgaca agctttacgt ccctgtagaa caaattgatc aggtccaaaa atatgttggc 62101 tccgaaggaa aagagccaaa gctgtataaa ttaggcggaa gtgaatggaa gcgggtcaag 62161 aaaaaagtag agacatccgt tcaggatatt gctgatgact taattaagct gtatgccgaa 62221 agagaagcga gcaagggcta tgcgttttct cctgaccatg agatgcagcg tgaattcgaa 62281 tcggctttcc cttatcaaga gactgaggat cagctccgtt ctattcacga aatcaaaaaa 62341 gacatggaaa gagaacgtcc gatggaccgc ttgctgtgcg gagatgtggg ctacggtaaa 62401 acagaggttg ccatacgtgc cgcgtttaag gcgatcggtg acggaaagca ggtagctctg 62461 ctcgttccga caaccatttt ggcacagcag cactatgaaa ccataaaaga gcgcttccag 62521 gactatccga ttaatatcgg ccttctcagc aggttcagaa cgagaaaaga agcaaacgaa 62581 acaatcaaag ggctgaaaaa tggaacggtt gatatcgtca tcgggacgca tcggctgcta 62641 tcaaaggatg tcgtgtataa agacttaggg ctcctcatca ttgatgaaga gcagcgtttc 62701 ggtgtaaccc ataaagaaaa gatcaagcaa ataaaagcca atgttgatgt attaacgtta 62761 acagcaacgc cgattccgcg tacgctgcat atgtctatgc ttggcgtaag ggacctttca 62821 gtcatcgaga ctccgccgga aaatcgcttc cccgtacaga cgtatgttgt ggaatataac 62881 ggcgctcttg tcagagaggc gattgaacgt gagcttgcac gcggaggcca ggtctatttc 62941 ttgtacaacc gggtagagga cattgagcgg aaagcggatg aaatttcaat gctagtccct 63001 gacgcgaagg tagcatatgc gcatgggaaa atgacagaaa atgaattaga aaccgttatg 63061 ctaagcttcc ttgaaggaga atcagacgtt ctcgtcagca caaccattat cgaaactggc 63121 gtggacatcc caaacgtcaa tacgctgatc gtatttgacg ccgacaagat gggactttct 63181 cagctttacc agctgcgggg gcgtgtcggc cgttctaacc gtgtggcgta tgcgtacttc 63241 acgtatcgcc gggataaagt gctgacagaa gtggctgaaa aaaggctgca ggctattaaa 63301 gaattcacag agttaggttc cggttttaaa atcgcaatgc gtgacttaac gattcgcgga 63361 gccgggaatc ttcttggtgc ccagcagcat ggcttcatcg attcggtcgg atttgacctc 63421 tattcacaaa tgctgaagga ggccattgag gagcgtaaag gagacacagc gaagacagag 63481 cagtttgaaa cagaaattga tgtcgagctt gatgcgtata ttccggaaac ttatattcaa 63541 gacggcaaac agaaaattga tatgtataaa cgcttcaggt ctgtggcgac aatcgaagag 63601 aagaatgagc ttcaagatga aatgatcgac cgctttggaa actatccaaa agaagtcgaa 63661 tacttgttta ctgttgcaga aatgaaagtc tatgcgagac aggaacgtgt cgagctgatt 63721 aagcaggata aagatgctgt cagattgacg atttctgaag aagcaagtgc tgaaattgac 63781 gggcagaagc tgtttgagct tggcaatcaa tatggcagac aaatcggact gggaatggaa 63841 gggaaaaaac tcaaaatctc catacagacg aaaggccgta gtgctgatga atggctcgac 63901 accgtgctgg gcatgctgaa gggcttaaaa gatgtgaaaa agcaaaccat ttcatcaacg 63961 taaattttgt tactctctgg tgtatattac atttgatgtg acggatacta atttcaagcg 64021 aggcggaagg tacataaagt aactgcttta ggtctttccc acatgtatat accatcaaat 64081 gaaagagagg caccagagat gaaagcaacc ggtatcgtac gtcgtattga tgacttaggt 64141 cgggtcgtga ttcctaaaga aattcgaaga actctgagaa tcagggaagg cgatccgctt 64201 gagatttttg tagatcgtga cggagaagtg attttgaaaa agtactctcc gatcagtgag 64261 cttggagact ttgcaaagga gtatgcagac gcgctttacg acagcctcgg ccattcagtg 64321 ctgatttgtg atcgtgatgt atatattgcc gtgtccggca gctccaaaaa agattactta 64381 aacaagtcaa tcagcgaaat gctggaaaga acaatggatc agcgcagctc cgtgcttgag 64441 agtgatgcga aatcagtaca gcttgtgaat ggaattgatg aggacatgaa ttcttatact 64501 gtaggcccaa ttgtggcgaa cggtgatccg ataggtgctg tggtgatctt ttcaaaagat 64561 cagacaatgg gcgaagtaga gcataaagcc gttgaaacag cagctggatt tttggctcgt 64621 caaatggaac agtaggtctt attcctttct tcgaaaatag gtatgtaaag aacagctctc 64681 cttgggacgc tgttcttttt catgcgtgcc gaaaaaggaa tccaagggtt gggatgtggt 64741 ataataacct cgtttttatt tgtgccgcgg taatacgtga accgtattgc ccctgacgtt 64801 gggaaggagc ttttggatgg acgattcaat aggcgttaaa cggcattgga tttggcaggg 64861 ggcttttgtt ttaattctgg caggcgtcat cacaaaaatt ttaagcgctg tttacagagt 64921 cccgtttcaa aacattgtcg gcgatgttgg attttatata tatcagcagg tatacccctt 64981 tcttggtatt gcggtcatgc tgtccacatc aggatttcca gtcattattt caaagctgat 65041 gaatgattat agtgaaaaaa atcatcacac catattaaaa atatcagcgt tgtttttgtc 65101 tttaatcggt attttattat ttctttgttt atatctgggt gctgttccta ttgcactctt 65161 tatgggagat tcgcatctag ccgtgttaat tcaagtggcc gcatacgcgt ttctgctttt 65221 cccatttgtc gcgttgctaa gaggcggttt tcaggggcgg cacgaaatgc tcccttcagc 65281 cttatcacag atgacagagc agtttctgcg tgttgcggtg ctcttgggtt tatcattttg 65341 gctcgtgaaa aagggagcct cgctttatac tgcgggagcg gcagccgctt caggctctct 65401 tgccggaagt ttggttgcat tgataatact ggggtttttt tggttcaaaa cgaaaagaga 65461 caaccaaacg gataggcaaa acgaaaatgt catcacaaca aaagaattga cgaaaaaact 65521 gcttttatat tcggtcacaa tttgtgtaag cagtttgctg cttttgttta tccagcttgt 65581 tgatgctttg aatttatatg cattgctttc gggtggtgag gcaagcgaag aagcaaaatg 65641 cctaaagggg atctatgatc ggggacaacc cttgttgcag ctcggttcag tttttgccgt 65701 aagcattgcg acgtcactcg ttccgtatat ttctatggct gtaaaaaaca aagagctgaa 65761 gatcatgaaa gaaaaaatca cgtcatcttt gaaactatgc cttgtgctcg gtacaggcgc 65821 atcggctggg ttgatttgca ttctaaagcc ggtaaatatc atgctgtttc aaaatggaga 65881 agggacaggt gcgttacaag tatttagctg ctccattttg tttgcatcct tggcggtaac 65941 ggcagcggca gtcttacagg gagcgggata cacagttttt cctgcgatag cggtgggcgc 66001 gggtgttgcg gtgaaatggg tgttaaacac acttttggtt ccgcgctatg ggattgaagg 66061 cgcatcgctt gcgacagcgg cttcctttgc ggctgtcgcc ggccttaact tgtatcagct 66121 tcggcaaaag gaatggctcg ataagcttag aggcgttttg attccgatta ttggatctgc 66181 tcttttgatg tcagctgttt tgcttgcgta tacgcgtctc tggactttct tgtttcctgc 66241 aacaggaaga ggagcggctg tgattgagag tctttctgct gttgccattg gtggcgcggt 66301 gtttatttat tgtatgatga gattgggaat atttacagat gaagagctga acagtgtgcc 66361 attcggcagc aagttaagca aattcatgag aaggagagaa caaaatggcg ggtaaaatta 66421 cagtcgtcgg acttggtgcc ggagacatgg accaattgac aattggtata cacaagctgc 66481 tgacgaaggc agatacgctg tatgtcagaa ccaaggatca tcctttaatt gaggagcttg 66541 aaaaagaaac gaagaacatc cgtttctttg atgatatata tgagaaacat gatcagttcg 66601 aggcggtata tgaagaaatt gcagatatcc tctttgaagc ggcgcggcgt gaggacgtgg 66661 tttacgctgt gccgggacac ccttttgtcg cagaaaaaac agttcagctg ctgacggagc 66721 ggcaggaaaa ggaaaacgtt caagtgaaag tcgcgggggg acaaagtttc cttgatgcca 66781 cattcaatgt cttgcaaatt gacccgattg aaggttttca atttgtggat gccggcacat 66841 tgtccgcgga tgagcttgag ctcagacatc atctgatcat atgtcaggtt tacgaccaaa 66901 tgacggcttc tgaagtcaag ctgacattga tggagaagct gcctgatgat tatgaggtcg 66961 tcattgtgac tgcagcaggc agccgtggcg aggagatcag gacagtgcca ttatttgagc 67021 tggaccgcaa tgtcgctttg aacaacttaa caagtgtgta tattccgccg attaaagaag 67081 agaagctgct ttatcacgaa ttctccacgt tccgaagcat catcagagag cttcgcggac 67141 ctaatggatg tccgtgggat aaaaagcaga cgcatcagtc attaaagcag tacatgattg 67201 aagaatgtta tgagcttctc gaagctattg acgaagaaga cacagaccat atgatcgaag 67261 agcttggcga cgttttgctt caggtcttgc ttcacgcgca aattggtgaa gatgaaggtt 67321 atttcacaat tgatgatgtc ataaaaggaa tcagtgaaaa aatggtccga agacatcccc 67381 atgtgtttaa agatgttaag gttcaggatg aaaacgatgt tttagccaat tgggaagata 67441 taaaaaaggc cgaaaaaaat acatctgaat catcattact agacagcgta ccgaaaaccc 67501 ttccagctct ttcgaaagca gctaaattgc agaaaaaagc agcgaaggtc ggttttgact 67561 gggaagacgt cagcgatatt tgggaaaagg taagtgagga aatgaaggaa ttttcttctg 67621 aggtttctga agctcctcac gaacacaatc ttaaagctga gtttggcgac attttgttcg 67681 cgctggtgaa tgtagcccgc ttctacaaaa tagagccaga ggaagcgctg accatgacta 67741 atgacaaatt ccggagacgg ttctcgtaca ttgaggaaac agcgaaggaa gagggagtcg 67801 agttggctga tatgtccctt gaggacatgg acaaactgtg gaatgaagca aaagaaactg 67861 agaggagatc atagatatga gattagataa atttttgaaa gtatcacggc tgatcaaacg 67921 gcgtacacta gcgaaggaag tagctgacca aggacgaatc tctattaacg gaaaccaagc 67981 taaagctagc tctgacgtaa aaccgggaga tgaactaacg gtccgcttcg gccaaaagct 68041 tgtaacggtt caagttaatg aattgaaaga cacgacgaaa aaagaagaag ctgcaaacat 68101 gtacacgatt ctaaaagaag aaaaactcgg cgaataggct tgttctaaaa aaacccccca 68161 cctcatacaa tgcagtaata atgctaaaag tatcgaggat atgggggctg aatagatgaa 68221 ttcatattat gatcaaaaag gttcttcgtc tgttccggaa cagcatgatg tgacaatgaa 68281 aggccggaag catttagata tttctggggt taagcatgtg gagagttttg ataacgaaga 68341 attcctgctg gaaacggtga tgggaatgct ctccgtcaga ggccaaaacc tgcagatgaa 68401 aaatcttgat gtggaaaaag ggattgtttc gattaaaggc agggtatttg atttagtgta 68461 cttagacgaa caacaagggg ataaagctaa agggtttttt agcaagttgt ttaaatgacg 68521 ctgacgacac aattctatac aatgctagcg atgtccggta tgggtctctg gcttggtgct 68581 tcgcttgata cataccggct ctttgtcatt cgtgccaaaa cagccagatg gctattattt 68641 attcatgata ttcttttctg gattatgcaa gggctgcttt tcttttatgt cttgcttcat 68701 gtaaatgagg gagaattcag gatttacatc tttttagcgg ttctgctggg cgttgcgacg 68761 tatcagagcc tttgcaaacg aatctatata aaaatactga aattcgtcat ttaccttgtt 68821 gtttctgttt atcaattctt caaaaaactc attcagcacg tgttatttcg tcctattgtg 68881 tggacatgcg gagcgatcat ctggctggcg gcatttttat tcaagaaaac atacagcctg 68941 ataggttttc tcctgctgtg tctatataaa atagtcatgg ttctgtgttt tccgatccgt 69001 tttatcgcga aacaatgttt gaaacttctt cctgtgaaaa tgcgtctaac ttttagacgt 69061 tattttgaaa aaggtgcagg atttctcaaa aagaagaaga aactattgat aaccataaga 69121 acgaccatca cacggttttt gaagagatga aaggaggacc gtctggtttg aatttttcca 69181 gggaacgaac gataactgaa atacaaaacg actataaaga acaagtagaa cggcaaaatc 69241 agctgaagaa acgaagacgc aaagggctgt acagacggtt aactgtattc ggcgccctag 69301 tattcctgac ggcaattgtg ctggcaagct ctgtatggtc ccaaacatct tcccttagtg 69361 caaaagaaga aaagaaagaa cagcttgaaa aagaactgaa aagtttaaag acaaaacaaa 69421 cggatttaaa agaagaaata tccaaattga aggatgagga ttacgtcaca gagcttgcca 69481 gaagggactt attcatgtct ggagacggag aaattatctt caatgtggag aagaagagca 69541 agtagccttg ttgacactta aatttttatt taggtataat taagcaaacg atctttttat 69601 aagcctaagg aggagcactt tttttatgtc gattgaagtt ggcagcaagt tgcaagggaa 69661 aattacaggt attacaaatt ttggagcatt tgttgaattg cctggaggct caaccggtct 69721 cgttcacatt agtgaggtag ctgataatta tgtcaaagac attaacgacc acttaaaagt 69781 cggcgaccaa gttgaagtga aagtcatcaa cgttgaaaaa gacgggaaaa ttggtttatc 69841 tattaaaaaa gctaaagacc gtccgcaagc cagacctaga aatgatttcc gtccgaaaga 69901 atcttttgaa cagaaaatga ataagttttt aaaagacagc gaagatcgct tgtcatcttt 69961 aaaacgcaat acggaatcaa aacgtggagg gcgcggagca agaagaggat aacttgctgc 70021 tttctataaa ataaatgaag catccgttca tcccgacgga tgctttttta ttatcctcat 70081 tctctttaag agtcagaaaa ttacaacatt aaagtttctg ttgacgaaag agacaaacct 70141 ttgtattata taacttgtgc ttagaagcac aaaacaatat ggcggtgtag ctcagctggc 70201 tagagcgtac ggttcatacc cgtgaggtcg ggggttcgat cccctccgcc gctaccatat 70261 ttgtttggcc cgttggtcaa gcggttaaga caccgccctt tcacggcggt aacacgggtt 70321 cgaatcccgt acgggtcatc ctaacaaatc ggtttctctt gcagaagccg atttttttca 70381 tttttagaca acattccgga aattcttttc ataaacgaat atcaaggcag aaaccgtcga 70441 agatttcttt ggtattgtta ccttcttttg acaaaatcct atctgtgctt tcgctataat 70501 gacaggcaac gaatataaca ggtgggagat gagaggaatg gaaaaagcag aaagaagagt 70561 gaacgggcca atggcgggac aagctttgga aaaactccaa tcgtttttta acaggggcac 70621 gaagctggtg actcatcatt tgcattcact gtttttctat aaaggattca tttatgttgt 70681 catcggattt ttgcttggac gggctttcat attatccgag gtgcttcctt tcgcacttcc 70741 tttctttgga gcgatgcttc ttatcagaag agacaaagcg ttttatgcgg ttttggctgt 70801 gcttgcaggt gcgctgacca tatctccaaa gcactcattg ctcatactgg cggcattgct 70861 ggcattcttc gtattttcta aagtggctgc cttcattacc gacgatcgtg ttaaagcgct 70921 cccgattgtc gtgttcttct ccatggctgc agcaagagcc gggtttgttt atgcccaaaa 70981 tggcgtattt acaacctatg attatgtaat ggctatcgtt gaggctggac tatcgtttat 71041 cttaacactg attttccttc agagccttcc gatttttact gtgaaaaaag tgaaacaatc 71101 attaaaaata gaggaaatca tttgctttat gattcttatt gcctctgttt taacggggct 71161 ggctggcttg tcctaccaag ggatgcaggc agaacatata ttggctcgtt atgttgtgtt 71221 gagtttttcc tttattggcg gagcaagcat cggctgtacg gttggggttg tgaccggcct 71281 gattcttggc ttggcgaata tcggaaacct atatcaaatg agtctgcttg ctttttccgg 71341 tttattgggc ggtttgctga aggaagggaa aaaagcgggt gcagcaattg gtttgatcgt 71401 tggatcactt cttatatctt tatatggtga aggctctgcc ggtctgatga caacgctcta 71461 tgagtcatta atcgcagtct gcctgttttt gctcacacct caatctatta cgaggaaagt 71521 ggcgagatat attccgggaa ctgtcgagca tcttcaagag caacagcaat acgctagaaa 71581 aatccgtgat gtcactgctc agaaggtaga ccaattctcc aatgtatttc acgcgctgtc 71641 tgaaagcttt gcaacctttt atcaagcatc agacgaacag acagatgaca gcgaagttga 71701 tctgttctta agcaaaatca cggagcattc ctgccagacg tgctacaaga aaaacaggtg 71761 ctgggtacag aactttgata aaacatatga cttaatgaaa caagttatgc ttgaaacaga 71821 ggaaaaagaa tatgcatcaa accgaaggct gaaaaaagag tttcaacagt attgttctaa 71881 atccaagcag gttgaagagc tgattgagga tgagctcgca catcatcatg cccatttgac 71941 actcaagaaa aaagtccaag acagcaggcg ccttgttgct gaacagcttt taggcgtttc 72001 tgaggttatg gccgactttt ctcgggaaat aaaaagagag cgagaacaac actttctgca 72061 ggaagagcaa atcatagaag cgcttcagca tttcggaatt gagattcagc atgtcgagat 72121 ctatagtctt gaacaaggaa atatcgatat tgaaatgacc attccgttca gcggacatgg 72181 agaaagtgaa aaaatcattg ctcctatgct ttctgacatt ctggaggaac aaattcttgt 72241 gaaagccgaa cagcactctc cgcatccgaa tggatacagc catgtcgcct ttggatcaac 72301 aaaatcatac agggtgtcca cgggagctgc tcacgctgcg aagggcggcg gccttgtctc 72361 cggtgacagc tacagcatga tggagcttgg agccagaaaa tatgctgcag caatcagtga 72421 cggaatgggc aatggcgcaa gagcgcactt tgaaagcaat gaaacgatca agcttcttga 72481 aaaaatcctt gaatcgggca ttgatgaaaa aatagcaatt aaaacgatca acagcatact 72541 gtctctaagg acaactgacg aaatatattc cacgcttgac ctatctatta tcgatcttca 72601 agatgccagc tgtaaatttt tgaaggttgg atcgacgccc agctttatca aacggggtga 72661 ccaggtcatg aaagttcaag cgagcaatct gccaatcggt attattaatg aattcgatgt 72721 ggaggttgtg agtgaacagc tgaaagcggg tgacctctta attatgatga gtgatggcat 72781 ttttgagggg cctaagcatg tggaaaatca cgacttatgg atgaagcgta aaatgaaagg 72841 gttgaaaaca aatgacccgc aggagattgc cgatttgctt atggaagaag tcatccgcac 72901 aagatccggc caaattgagg acgatatgac tgttgttgtc gtccggattg atcacaatac 72961 accgaagtgg gcatccattc ctgttccggc aatctttcaa aacaaacaag aaatttcata 73021 acgcttccgt ataaatcaaa tttcttctgg cgaagatggg aatatatgaa tctgagaatc 73081 ctcgtattct ccaggaggaa tgaatgtgaa caacggacat ttaaatcaaa ttttgctgat 73141 aacggatggc tgctcaaacc atggggaaga cccgcttgca atggctgctt ttgctaaaga 73201 gcaggggatt acggtaaatg tcattggtat aatggaagaa aatcaaattg accctgaggc 73261 aatgaaggaa gtcgaaggga ttgcacttgc cggaggaggc gtgcaccaag tcgtttatgc 73321 atctcagctt tcacaaactg ttcaaatggt aacaaagaaa gcgatgacgc aaaccttaca 73381 aggtgtagtc aatcaagaac tgaaacagat tctcggaaag aatgtggaaa tggaagagct 73441 ttctccggaa aaacgcggcg aagtcatgga agtggtagac gagcttggag aaacggtgca 73501 tcttcaggtt ttggttcttg ttgatacaag tgcaagtatg gcgccaaagc ttccaacagt 73561 aaaagaggcg ctgattgatt tgtctgtaag cctcaattcc cgaattggga ataacgaatt 73621 tgcgatgtgt atatttcccg ggaaaaaaca agaggtcgag cttgtgctga actggacacc 73681 gaagctgcaa tctctttcca cactctttgc aaagctttcg acaggcggca tcacgccgac 73741 aggtccggcg attcgtgaag cgacactgca gtttgaaaaa atacgctcaa gaaggggcat 73801 gctggcagat gatgaacgac gctttgacga gtttggcatg tagcctcaag ccgggtacga 73861 caatcaaagg caagtggaat ggaaacactt atacattgcg taaacagctt ggtaaagggg 73921 ccaatggaat tgtgtatttg gcagaaacat cagatggaca tgttgcctta aaggtgagtg 73981 atgacagcct gtctattact tctgaagtga atgtcttgaa atctttctca aaggcccagt 74041 ccgttacgat ggggccttct ttttttgata cggatgatgc ctatattccc agtgccaata 74101 cgaaagtttc attttatgca atggaataca taaaagggcc gctgcttttg aagtatgtca 74161 gtgataaagg agcagagtgg ataccggtat taatgattca gctgttatcc agcttatcgg 74221 tgcttcacca gcaaggatgg atattcggcg atcttaaacc tgataatctg atcgtaactg 74281 gtccgcccgc aaggatccgc tgcattgatg tgggcggcac gacaaaggaa ggccgggcga 74341 taaaagagta tacggagttt tatgacagag gctattgggg gtatggaaca agaaaggcag 74401 agccatccta tgatctgttc gcagttgcca tgattatgat caacagtgtg cataaaaaag 74461 aatttaagaa aacgaaccag cccaaagaac agcttaggtc tctcatcgaa ggaaacccgc 74521 tgcttcaaaa gtataaaaaa gcgctttttt cagccttgaa cggagattat caatccgcag 74581 atgaaatgaa aaaggatatg ctagacgcgg ggcaaaaagc agcacaaaga aaacagccta 74641 taaaagcatc accgcagcct gccacacgac aaagacagca aaaaccgcgc caaggaaaaa 74701 taacgaagac gcgatatacc ccaaaacaga aaccggctaa gtcggggggg ttatttgaaa 74761 caacgcttat cgtgatcagt gttttagcgc tttatttcgc ctatattatc tttttcttaa 74821 tctgaatggt gcaaactgca gagcctatgc ttcttctttg cttggagggg ttgaaagtgt 74881 taggatatga atatctttaa aatacctgct cattgtgagg aggacattgt gaaaagtgtc 74941 aaagattttt taaacaaaca caatcttacg ttaaaagggg cgacaatcat tgtaggcgtt 75001 tccggcggtc cggactcaat ggctcttctt cacgcgttgc atacgttatg cggccgttca 75061 gcgaatgtta ttgcagctca cgttgaccat cggttcagag gtgcggaatc cgaggaggac 75121 atgcgttttg tccaagctta ttgtaaagct gaacagctcg tgtgcgaaac ggctcaaatc 75181 aatgtaaccg catatgcaca ggaaaaagga ctcaataagc aggctgcagc acgcgattgc 75241 cgctaccagt tttttgagga aatcatgtcg aagcaccaag cggactatct ggctcttgcg 75301 catcatggtg atgaccaggt tgaaacaatg cttatgaaac tggctaaggg tacgcttgga 75361 acgggacttg cgggaatgca gccggttaga cgttttggga cagggcggat catcaggccg 75421 ttcttaacca ttacaaagga agagatcctt cactattgcc atgaaaacgg cttgagctac 75481 cggacggatg aaagcaacgc caaagatgac tacacaagaa acagattcag aaaaacagtg 75541 ctcccgtttt tgaagcagga atctccggat gtgcataaaa ggtttcagaa agtgagtgaa 75601 gcactgacgg aagatgagca attcttacag tcattaacga aagatgaaat gaataaagta 75661 atcacaagcc agtctaatac atcagttgaa atcaattcct ctcaattgct tgccctcccg 75721 atgcctttac aaagaagagg agttcaacta atattaaact atctttatga aaacgttcca 75781 tcatcctttt cagcccatca cattcagcag tttctcgatt gggcggaaaa tggcggtcct 75841 tcaggagtac tggactttcc gaaagggctg aaggtggtca aatcatatca gacatgtttg 75901 tttacatttg aacaatggca gtgcaaaaat gttccctttg aataccaaat tagcggagct 75961 gctgatgaaa cggcagtgct ccctaatgga tatctgatag aggcaaggca ttatgcggac 76021 tcgcctgaag aacatgggaa tgctgttttt atcacaagtg aaaaaaaggt gcgatttccc 76081 ttaacaatcc ggacgagaaa agctggagac cggatcaaac taaaagggat gaacggctca 76141 aaaaaggtaa aggatatatt tattgataag aaattgcctc tccaagaaag agacaactgg 76201 ccgattgtga cggacgcaag cggtgaaatt atctggatac ctggcttgaa aaaatcaatt 76261 tttgaagatc ttgtgattcc aaacagcgac cgcattgtat tacaatatag acagcatgaa 76321 aagtgtaggg ggcaagcaaa atcatgatga aacatgatat cgagaaagta ctgatctcag 76381 aggaagagat acaaaagaaa gtaaaagagt taggtgcaga attaacgagc gagtatcaag 76441 atacatttcc gttggcaatc ggtgtgttaa aaggagcact tccttttatg gcggatctta 76501 tcaagcatat tgatacatat ttggaaatgg atttcatgga tgtatcaagc tacggaaatt 76561 ctacggtttc ttctggagaa gtaaaaatca ttaaagattt ggatacatct gtagagggcc 76621 gggacatctt aattattgaa gatatcatcg acagtgggtt aaccttaagt tatctcgtag 76681 agctcttccg ataccgtaaa gcaaaatcaa ttaagattgt tacccttttg gataaaccga 76741 gcggaagaaa agcggacatc aaagcagact ttgtcggttt tgaagttcct gacgcgtttg 76801 tagtgggtta cggacttgat tatgctgagc gctatcgcaa tctgccttat atcggagtgt 76861 taaaaccggc agtttatgaa agctgatcgg cagcctgctt ccgagatggt tattgtttgt 76921 attggaatga ttttctatgg tactattgaa catagttgtg cttactgtgg gaggaggtaa 76981 ggaatgaatc gggtcttccg taataccatt ttttatttac ttattttatt agtagtaatc 77041 ggggttgtga gctacttcca gacctcaaat ccgaaaacag aaaatatgtc gtacagtacg 77101 ttcatcaaaa acctggatga cgggaaagtt gatagcgtat cggttcagcc tgtcagaggt 77161 gtttatgagg taaaagggca gctgaaaaac tacgacaaag atcaatactt tttgactcat 77221 gttcctgaag gaaagggagc agaccagata tttaacgctt tgaaaaagac agacgtaaag 77281 gttgagcccg cgcaagaaac aagcggatgg gtgacgttcc tgacgaccat catcccattt 77341 gtcattatct ttattctgtt tttcttcctg ctcaatcagg ctcaaggcgg cggcagccgt 77401 gtcatgaact ttggcaagag taaagcgaag ctgtatacag aggaaaagaa acgcgtcaaa 77461 tttaaagacg ttgcaggggc tgacgaagaa aagcaagaac ttgttgaagt tgttgagttt 77521 ctgaaagatc cccgcaagtt tgccgagctc ggcgccagaa taccgaaagg cgtgctttta 77581 gtcggacctc cgggtaccgg taaaacattg cttgccaagg cttgtgcagg agaagccggc 77641 gtacctttct tcagcatcag cggatctgat ttcgttgaaa tgtttgtagg ggtcggtgct 77701 tcccgtgtgc gtgacttgtt tgaaaatgcg aaaaagaatg cgccttgttt gatcttcatt 77761 gatgaaattg acgcagtcgg acgccagcgt ggcgctggtc tcggcggtgg acacgatgaa 77821 cgtgaacaga cgctaaacca attgcttgtt gaaatggacg gattcagcgc taatgaagga 77881 attatcatca ttgctgcgac gaaccgtgcg gacatcttgg acccagcctt acttcgtccg 77941 ggacgttttg accgtcaaat cacagtggac cgcccagatg tcattggccg tgaagctgta 78001 ttgaaagtcc atgcgagaaa caaaccgctg gatgaaacgg ttaacctaaa atcaattgcc 78061 atgagaacac caggcttctc aggcgctgac ttagaaaacc tcttgaatga agctgcgctt 78121 gtagcggctc gtcaaaacaa gaaaaaaatc gatgcgcgtg atattgacga agcgacggac 78181 cgtgtaattg ccggacccgc taagaagagc cgcgttatct ccaagaaaga acgcaatatc 78241 gtggcttatc acgaaggcgg acacaccgtt atcggtctcg ttttagatga ggcagatatg 78301 gttcataaag taacgattgt tcctcggggc caggctggcg gttatgctgt tatgctgcca 78361 agagaagacc gttatttcca aacaaagccg gagctgcttg ataaaattgt cggcctcttg 78421 ggcggacgtg ttgctgaaga gattatcttc ggtgaagtca gcacaggggc gcacaatgac 78481 ttccagcgtg cgacgaatat tgcaagacga atggttacag aattcggtat gtcagaaaaa 78541 ctgggaccgt tgcaatttgg acagtctcag ggcggtcagg tattcttagg ccgtgatttc 78601 aacaacgaac agaactacag tgatcaaatc gcttacgaaa ttgatcagga aattcagcgc 78661 atcatcaaag aatgttatga gcgtgcgaaa caaatcctga ctgaaaatcg tgacaagctt 78721 gaattgattg cccaaacgct tctgaaagtt gaaacgcttg acgctgaaca aatcaaacac 78781 cttatcgatc atggaacatt acctgagcgt aatttctcag atgatgaaaa gaacgatgat 78841 gtgaaagtaa acattctgac aaaaacagaa gaaaagaaag acgatacgaa agagtaattc 78901 gctttctttc taaaaaaact gccggctgac gctggcagtt tttttatgta aatgattggc 78961 tcagctgcgg cttttacaat catccaattc tggtatcgat ttgtttacaa atgagccgct 79021 gatcgtgtat ggtattgtag aatgtttgta aaaagtaaag tagagaaact attcaaaagt 79081 ggtgatagag gttgttactg gttatcgatg tggggaacac caatactgta cttggtgtat 79141 atcatgatgg aaaattagaa tatcactggc gtatagaaac aagcaggcat aaaacagaag 79201 atgagtttgg gatgattttg cgctccttat ttgatcactc cgggcttatg tttgaacaga 79261 tagatggcat tattatttcg tcagtagtgc cgccaatcat gtttgcgtta gaaagaatgt 79321 gcacaaaata ctttcatatc gagcctcaaa ttgttggtcc aggtatgaaa accggtttaa 79381 atataaaata tgacaatccg aaagaagtag gggcagacag aatcgtaaat gctgtcgctg 79441 cgatacactt gtacggcaat ccattaattg ttgtcgattt cggaaccgcc acaacgtact 79501 gctatattga tgaaaacaaa caatacatgg gcggggcgat tgcccctggg attacaattt 79561 cgacagaggc gctttactcg cgtgcagcaa agcttcctcg tatcgaaatc acccggcccg 79621 acaatattat cggaaaaaac actgttagcg cgatgcaatc tggaatttta tttggctatg 79681 tcggccaagt ggaaggaatc gttaagcgaa tgaaatggca ggcaaaacag gaaccaaagg 79741 tcattgcgac aggaggcctg gcgccgctca ttgcgaacga atcagattgt atagacatcg 79801 ttgatccatt cttaacccta aaagggctgg aattgattta tgaaagaaac cgcgtaggaa 79861 gtgtatagga ggtttagtaa tggattattt agtaaaagca cttgcgtatg acggaaaagt 79921 tcgggcttat gcagcgagaa cgactgatat ggtaaatgag gggcagagac gccatggtac 79981 gtggccgaca gcatccgctg cactaggccg tacaatgaca gcttcactta tgctcggcgc 80041 tatgctgaag ggcgatgata agctgaccgt gaaaatcgag ggcggaggtc cgatcggagc 80101 tattgtagct gatgccaatg ccaaaggaga agtcagagcc tatgtctcta acccgcaagt 80161 tcattttgat ttaaatgaac aaggtaagct tgatgtcaga cgtgcggttg gaacaaacgg 80221 aacgttaagt gtcgtaaaag atttaggttt gcgcgagttc ttcacaggac aagtagaaat 80281 cgtttcagga gaattaggag atgattttac ttactatctt gtgtcatctg agcaggttcc 80341 ttcatcagtg ggcgtaggtg tgctcgtaaa tcctgacaat accattcttg cggcaggggg 80401 ctttattatt cagctgatgc cgggaacaga tgatgaaaca atcacaaaaa ttgaacagcg 80461 tctatctcaa gtagagccga tttctaagct catccaaaaa gggctgacac cagaagaaat 80521 tttagaagaa gtcctaggcg agaaacctga gattttggaa acgatgcctg tcagattcca 80581 ttgcccttgt tcaaaagaac ggttcgaaac agccatttta ggactaggca aaaaagaaat 80641 tcaagatatg atagaagaag atggacaagc cgaagcagta tgccattttt gtaatgaaaa 80701 gtacttattt acaaaagaag agctggaagg gcttcgtgac caaactaccc gctaagctct 80761 ttagcgggtt tttaatttga gaaaaggggc tgaaagcagg tttgaaatca agaacaatct 80821 ggaccattat tttaggggcg ctgttggttt gctgtattgc tgttgcatat acgctgacga 80881 aatcccaagc cggcgcatcg tcatccggtg agtctattgc gactatcgga ggcaagagtg 80941 tgacaagaga agaatggctg aaagaaatgg aagatcagta tggtaagtca acgcttgaag 81001 atatgatcaa tgtccgagtt gttgagcagc tggctaaaaa gaacaaactt aaaatatcca 81061 aaagcgaagt tgatcgtgag tttttgctga ttaaagcggt caataattcc ttttacgaag 81121 atgaacatac gacggagaaa gagtggaaag accaaattcg ttataatatc ctccttgagg 81181 atttgttaac aagggatatc gatatctcaa acaaagaatt ggaatcattc tataataaaa 81241 ataaggaact atatcagttt gatgattcgt atcgaattcg gcacattgtt gtaaaagatg 81301 aagaagaagc aagagaagtc ctgaaagaac tgaaaggcgg atcaagcttt gaagctgtcg 81361 ctgccgaaag atctacagac agatatacat caccatacgg cggagattta ggttttgtca 81421 cagaggcatc agacaacatt ccatcagcat acattgaaga ggcgaaaaca ctcaaagagg 81481 atgaatggtc tcaggaacca ataaaggtca gcaacggata tgccattatc cagctgaaag 81541 aaaaactaaa ggcaagaacg ttctcatttg atgaagtaaa ggaccagatc agacggcaaa 81601 tcgcaatgga tcagctaggc gataaagcga cagttaagac actttggaaa gaagccgatg 81661 tatcttggtt ttatggggaa aaaagtacta agtgattgac aaaaaatttt gaaattgata 81721 gattatatac ataataccaa tacaaatagt cggaaattga ggtgtcgaga atggtacgtg 81781 tagcaaactc cattactgaa ttaattggga atacgccaat cgttaaatta aatcgccttg 81841 cagatgaaaa cagtgcggat gtatatctaa aacttgaata catgaaccct ggaagcagtg 81901 taaaagaccg tatcggttta gctatgattg aagcggctga aaaagaagga aaattaaaag 81961 ccggtaatac aatcattgaa ccgacaagcg gaaatactgg aatcgggctt gcaatggttg 82021 ctgctgctaa aggattaaaa gccattttgg ttatgcctga tacaatgagc atggagcgcc 82081 gcaaccttct tcgcgcatat ggtgctgagc ttgtgctgac tcctggtgcg gaaggcatga 82141 aaggtgctat taagaaagct gaagagcttg ctgaaaagca cggatacttt gtgccgcagc 82201 agtttaacaa cccttctaac cccgaaattc accgccaaac aacgggtaaa gaaatcgttg 82261 agcaattcgg tgatgatcag cttgacgcat ttgtagccgg aatcggaacg ggcggaacga 82321 ttacgggagc gggcgaagtg ctgaaggaag catacccttc catcaagatt tatgctgttg 82381 aaccgtcaga ttccccagtg ctttcaggag gaaaaccagg cccccacaaa attcagggaa 82441 tcggagcagg attcgtgccg gacatcttaa acactgaagt atatgatgaa atcttccctg 82501 tgaagaatga agaagcattc gaatatgccc gcagagctgc acgtgaagaa ggaattctcg 82561 gaggcatctc atcaggtgcg gcaatttatg ctgctcttca agtagcaaaa aaactcggaa 82621 aaggcaaaaa agtattggcc atcattccaa gtaacggcga acgttatcta agcacgccgc 82681 tgtaccaatt cgattaaaaa aagccaaaac tcccggttcg ccgggagttt ttttatattt 82741 cgtgcatcaa atatgccatg tctgcgacga atgttattct tggaagagaa attcactttt 82801 ttcactaaca acattgcttt acaattaaaa acaagtaaaa aagaaaatag aggaatgata 82861 caaatggcac aacgcagacc ggcaggcaaa aaaatacctt ttcaaaaaga ctcattctta 82921 caacaatttg agaaacttgc gcaatcccgg aaacatcatg tacttctcga aagtgcaaga 82981 ggcggcagat atagtatagc cggtcttgat ccaattgcga ctgtgaaagg aaaagacgga 83041 ataactacaa ttaagcatgg tgatgagatg ctgtttaaag aaggtgatcc attacgggcc 83101 ttccacagct ggtttaaaac actggaaaca gaaacgaatc atgagttccc tgactttcaa 83161 ggcggggcaa tcgggtttct cagctatgat tacgcacggt acattgaaaa ttttaaaatg 83221 ctctcattag atgatttaga aacaccagat atttattttc ttgtttttga tgatatagca 83281 gtttatgacc atcaagaaga gtctctatgg ctgattactc atgttaatgg ttctgatcag 83341 gaaacagcgg atgtgaagct atctgagtta gagcagatgt ggttgactga gcttcccgct 83401 gtcacttcgc gagagatgaa gcctgaaaca gctggttctt tcgcggcgcc atttaccgag 83461 gatgggttct cacaagctgt agagaaaatc aaacaataca ttgccagcgg agatgtgttt 83521 caagtcaatc tatcaataag gcagtcacag tcactgtctg tccacccata tcaaatttac 83581 aaaaccttga gagaagtaaa tccttctcct tatatggcgt atttagaaac acctgatttc 83641 caaatcattt gcggatcgcc tgaactgctt gtcagcaaaa agggcaagct attagagacg 83701 agaccgattg cgggcacccg ttccagaggg aaaacaaatg aagaagacga ggcgcttgca 83761 aacgaattga tacacaatga aaaagaacgc gcggaacatg tcatgctggt tgatcttgag 83821 cgaaatgatc tgggaagagt atcacgttac gggtctgtgc gcgtaaatga attcatggca 83881 attgaaaaat actcgcatgt gatgcacatt gtgtctaatg tccaaggtga actgcaggat 83941 gggtatgatg ctgtagatat tattcatgct gtgtttcccg gaggaaccat tactggtgca 84001 ccgaaagtaa gaacgatgga aattatagaa gaacttgagc cgacacgccg agggctttat 84061 actggatcta taggatggtt tggatataat cacgatctgc agtttaatat cgtcattcga 84121 accatttatg caaccggagg gcaggcattt atgcagtccg gtgcaggagt tgtgattgat 84181 tctgttccga agcacgaata caaggaatca ttcaaaaaag cttttgcgat gcaaagagca 84241 ttagagctga gcgaagaaga gacaaaaatt agatgaggtg agcggagaaa tgattttaat 84301 gattgataac tacgattcat tcacgtacaa cttggtacag tatttgggcg agcttgggga 84361 agagctggtt gtgaaacgca atgacagcat cacaatcgat gaaattgaag aactgtctcc 84421 ggactttctg atgatatctc ccggaccgtg cagccctgat gaggcgggaa tcagcctcga 84481 agcaattaaa catttcgcag ggaaaattcc tattttcggt gtatgtctcg gacatcagtc 84541 catcgcacaa gtgttcggtg gtgatgttgt tagggcagaa cggcttatgc acgggaaaac 84601 ctcggatatc gagcatgacg gcaaaaccat ttttgaaggg ttgaaaaatc cccttgttgc 84661 gacgcgatac cactcgctga tcgtaaaacc tgagacgctg ccaagctgtt ttacagtaac 84721 agcacaaacg aaagaaggag aaatcatggc tattcgccac aatgacctcc cgatagaggg 84781 tgtgcaattt cacccagagt ctattatgac ctcctttggg aaagaaatgc tcagaaattt 84841 tattgagaca tatcgcaagg aagttattgc gtgatgatat atgtgaacgg ccggtatatg 84901 gaggagaaag atgcagttct ttctcctttt gaccatgggt ttttatatgg gatcggtgtt 84961 ttcgaaacct tcaggctcta cgaaggctgc ccgtttttgc ttgattggca tatagagagg 85021 cttgaacgcg cgcttaagga tctgcaaatc gaatatactg tttcaaagca tgagatcctt 85081 gagatgctgg acaagctgct taagctaaat gatatcaagg atggcaatgc ccgcgtcaga 85141 ctgaacatat cagcgggaat cagcgataaa ggctttgtcg cccagacgta cgataagccc 85201 accgttttat gctttgtgaa tcagctgaaa ccagaaagtc ttcctttgca aaaagaagga 85261 aaggttttat cgatacggag aaacactcca gagggatcgt tccggttaaa atctcatcat 85321 tatctaaata atatgtatgc gaaacgggaa attggaaatg atccgcgtgt cgagggaatt 85381 ttcttaacgg aggatggagc tgttgcagag ggtatcatat ctaatgtctt ctggagaaaa 85441 ggtcgctgta tctatacgcc atcgcttgat accggtattc tggacggcgt cacgagacgt 85501 tttatcatag aaaatgcaaa ggatatcggc ctggagctca aaacgggccg atatgagcta 85561 gaagctctct tgacagctga cgaagcgtgg atgacgaact cggttcttga aatcatcccg 85621 tttactaaaa tagaagaagt aaactatgga agccaaagcg gagaagcaac ctccgctctt 85681 caattgttat acaaaaaaga aataaagaac atgattcatg aaaagggagg aagagcatgg 85741 cgcagcacac aatagatcaa acacaagtaa tccacactaa gcccagcgct ttatcatata 85801 aagagaagac gctggtgatg ggaattttaa acgtaacgcc tgactctttc tcggacggcg 85861 gaaaatatga cagcttggac aaggcgctgc tgcacgcgaa agagatgatc gatgatggtg 85921 cccatatcat tgatattgga ggggaatcga caaggcctgg cgctgagtgc gtatctgagg 85981 atgaggagat gtccagagtc attccggtga ttgagcggat tacgaaagag cttggtgttc 86041 ctatttctgt agacacgtac aaggcttctg tcgcagatga agcagtgaaa gccggtgcat 86101 ccattatcaa tgatatttgg ggagccaaac atgatccgaa gatggcttcc gttgcagctg 86161 aacataatgt tccaattgta ctcatgcata accgccctga aagaaactac aatgacttat 86221 tgccggatat gctgtcggac ttaatggaga gtgtaaaaat tgctgttgag gccggagtag 86281 acgagaagaa cattattctt gatcctggta tcggtttcgc gaaaacctat cacgataact 86341 tggcagtgat gaacaaacta gagattttca gcggattggg atatccggtt cttctggcaa 86401 cctcccgaaa aagattcatc ggacgtgttc tggatcttcc gcctgaggag cgggctgagg 86461 gcacaggcgc gactgtgtgt ctcggcattc aaaaaggctg tgacattgtc agggtccatg 86521 atgtaaagca aattgccaga atggcgaaaa tgatggacgc gatgctgaat aagggagggg 86581 tgcaccatgg ataaagttta tgtagaaggt atggagtttt acggatatca cggtgtgttc 86641 acagaagaaa acaaacttgg ccagcggttt aaagtcgatt taaccgctga gctggattta 86701 agcaaagctg gacagacaga cgaccttgag caaacgatca actatgctga gctctatcac 86761 gtatgtaaag atatcgtgga aggggagcct gtgaaattgg tggaaacgct ggcggaacgt 86821 attgctggca ctgttctcgg aaaatttcag cctgttcagc aatgtacggt gaaagtgatt 86881 aagccagacc cgccaattcc cggacactat aaatcagtag caattgaaat tacgagaaaa 86941 aagtcatgaa caacatagct tatattgcac ttggatctaa tattggagat agagaaacgt 87001 atttaaggca agcagtggct ttactgcatc agcatgctgc ggtgacagtc actaaagtgt 87061 cgtctattta cgaaactgac ccggtcggat acgaagatca agctcaattt ttgaatatgg 87121 ctgttgaaat caagacatca ttgaaccctt ttgaactcct tgaactgacg cagcagatag 87181 aaaatgaatt aggcagaaca agggaagtaa gatgggggcc gcggacggca gaccttgaca 87241 ttttgttatt taatcgtgaa aatattgaaa cagagcaact aattgttccg catccgagaa 87301 tgtatgagcg tttgtttgtc cttgcgccgc ttgcggaaat ttgccagcag gttgaaaaag 87361 aggctacaag cgccgaaaca gaccaagaag gtgtaagagt atggaagcag aaatctgggg 87421 tagacgaatt cgtgcattca gaaagctgaa aggttatact caagaaggat ttgcaaaagc 87481 attaggtata tcagtttcta ttctcggcga aattgaacgc ggaaaccgat tgccgtctgc 87541 tgccatcatt caagatgcag cagatgtttt aaatataagt gcggacgaat tggcgccgcc 87601 agaaaaatag aacaaatgaa aggaggagaa aaattgttca aaatcggaga tattcaattg 87661 aaaaaccggg ttgtgctcgc acctatggct ggtgtctgca actctgcgtt cagattgact 87721 gtaaaggaat tcggagccgg attggtatgc gctgaaatgg tcagtgacaa agcgatcctt 87781 tacaacaatg caagaacaat gggtatgctt tatattgatg aacgtgagaa accactgagc 87841 cttcaaattt tcggaggaaa aaaggaaacc cttgtggaag cggcgaagtt tgtagaccaa 87901 aacacaactg ctgatatcat tgatattaac atgggatgtc ccgtgccgaa gattacaaaa 87961 tgcgatgcgg gagccaaatg gcttctcgat cctgataaga tttacgaaat ggtttctgca 88021 gtagtggatg ctgttaataa gccagttaca gtgaaaatga gaatgggctg ggatgaagac 88081 cacattttcg cagtgaaaaa tgcacaggct gtagaacgtg cgggcggtaa agcagtggcg 88141 cttcacggcc gtacgagagt gcagatgtac gaaggaacgg caaactggga tatcatcaaa 88201 gaagtaaaac aatcagtatc gattccggtt atcggaaacg gcgatgttaa gacaccgcag 88261 gatgctaagc gtatgctcga tgagacagga gtagacgggg tcatgatcgg acgcgctgca 88321 ttgggtaacc cgtggatgat ttaccgtacg gttcagtatc ttgaaacagg taaattaaaa 88381 gaagagccgc aagtacgcga aaaaatggcc gtatgcaaac tgcatcttga ccgcctgatt 88441 gacttaaaag gtgaaaacgt agcggtaaga gaaatgagaa agcacgctgc atggtatctg 88501 aaaggcgtga aaggcaatgc gaacgttcgt aatgaaatca atcattgcga gacgagagaa 88561 gagtttgtac agcttttaga tgcatttacg gttgaagttg aggcaaaaga gcttcaaaat 88621 gcaaaagtag gataatactc acctctattt gctgctcact gctagtttta cgctggcagt 88681 ttttctgctt ttttcatgaa acaatatctg taatggagtg ataacaatga gtcaagaaga 88741 gcataaccat gaagaattga atgatcagct gcaagtcaga cgcgataaaa tgaatcagct 88801 gagagataac ggcatcgatc cattcggcgc acgttttgaa agaactcatc agtctcaaga 88861 agttatttcg gcatatcaag atctaaccaa agaagagtta gaagaaaaag cgattgaagt 88921 tacaatcgca ggccgcatga tgacaaaacg cggcaaagga aaagccggct ttgcccatct 88981 tcaggattta gaaggccaaa tccaaatcta cgtaagaaaa gacagtgtcg gtgacgacca 89041 atatgaaatc ttcaagtctt ctgacctcgg tgatcttatc ggcgtaaccg gaaaagtctt 89101 caaaacaaat gtaggcgaat tgtctgttaa agcaacttcc tttgaattgc tgacaaaagc 89161 gcttcgtccg cttcctgaca aataccatgg tttaaaagac gttgagcagc gctaccgtca 89221 gcgctatctg gatcttatcg taaacccaga cagcaaacat acgttcatta cacgaagcaa 89281 gatcattcaa gctatgagaa ggtaccttga tgatcatgga tacttagaag tagaaacacc 89341 tacaatgcac agcattcctg ggggagcttc tgcacgtccg tttatcactc accacaacgc 89401 gttagacatt ccactctata tgcgtattgc tatcgaactg cacctaaaac gtctaattgt 89461 cggcggttta gaaaaagtat atgaaatcgg ccgtgttttc cgtaacgaag gtgtctctac 89521 acgccataac cctgaattta caatgattga gttatatgaa gcatatgcgg actataaaga 89581 tatcatgagc ttaactgaaa accttgtcgc tcatatcgcc caagaagtgc ttggcacaac 89641 tacgattcaa tacggggaag agcaaatcga ccttaaaccg gagtggaaaa gaatccatat 89701 ggttgacgca gtcaaagaag cgaccggcgt tgatttctgg gaagaggtta ctgttgagca 89761 ggcgcgtgaa tatgcaaaag aacatgaagt agaaattaaa gactctatga cagtaggcca 89821 tatcatcaac gaattcttcg aacaaaaaat tgaagaaacg cttattcagc caacgtttat 89881 ttacgggcat cctgtagaaa tttctcctct tgctaagaaa aaccctgagg acccgcgttt 89941 tacagaccgt tttgagctgt ttatcgttgg ccgtgaacat gccaacgcgt ttacagagct 90001 gaatgatcct attgatcaaa gagaacgctt tgaagcgcaa ttaaaagagc gtgaagccgg 90061 taatgatgaa gctcatttaa tggatgaaga ctttgttgaa gctctggaat acggtatgcc 90121 gccaacagga ggtttaggca tcggtatcga ccgtctggtt atgctgctga cgaatgcccc 90181 ttctattcgc gatgtgctgt tattcccgca aatgagacaa cgctaataaa aaagagcggt 90241 atcctccata gggaaaggat gccgctcttt ttaaatccct tagtatttct tcaaaaaaac 90301 tattgcacta ttatttacta ggtggtatat tattattcgt tgccgctaaa caaggcgata 90361 acgaaaaaaa gaacttcaaa aaaagttatt gacttcactg agtcaacgag ttataataat 90421 aaagtcgctt gaacgaagtg aacaaaatga tctttgaaaa ctaaacaaga caaaacgtac 90481 ctgttaattc agtttttaaa aatcgcacag cgatgtgcgt agtcagtcaa actactttat 90541 cggagagttt gatcctggct caggacgaac gctggcggcg tgcctaatac atgcaagtcg 90601 agcggacaga tgggagcttg ctccctgatg ttagcggcgg acgggtgagt aacacgtggg 90661 taacctgcct gtaagactgg gataactccg ggaaaccggg gctaataccg gatggttgtt 90721 tgaaccgcat ggttcaaaca taaaaggtgg cttcggctac cacttgcaga tggacccgcg 90781 gcgcattagc tagttggtga ggtaatggct caccaaggca acgatgcgta gccgacctga 90841 gagggtgatc ggccacactg ggactgagac acggcccaga ctcctacggg aggcagcagt 90901 agggaatctt ccgcaatgga cgaaagtctg acggagcaac gccgcgtgag tgatgaaggt 90961 tttcggatcg taaagctctg ttgttaggga agaacaagtg ccgttcgaat agggcggtac 91021 cttgacggta cctaaccaga aagccacggc taactacgtg ccagcagccg cggtaatacg 91081 taggtggcaa gcgttgtccg gaattattgg gcgtaaaggg ctcgcaggcg gtttcttaag 91141 tctgatgtga aagcccccgg ctcaaccggg gagggtcatt ggaaactggg gaacttgagt 91201 gcagaagagg agagtggaat tccacgtgta gcggtgaaat gcgtagagat gtggaggaac 91261 accagtggcg aaggcgactc tctggtctgt aactgacgct gaggagcgaa agcgtgggga 91321 gcgaacagga ttagataccc tggtagtcca cgccgtaaac gatgagtgct aagtgttagg 91381 gggtttccgc cccttagtgc tgcagctaac gcattaagca ctccgcctgg ggagtacggt 91441 cgcaagactg aaactcaaag gaattgacgg gggcccgcac aagcggtgga gcatgtggtt 91501 taattcgaag caacgcgaag aaccttacca ggtcttgaca tcctctgaca atcctagaga 91561 taggacgtcc ccttcggggg cagagtgaca ggtggtgcat ggttgtcgtc agctcgtgtc 91621 gtgagatgtt gggttaagtc ccgcaacgag cgcaaccctt gatcttagtt gccagcattc 91681 agttgggcac tctaaggtga ctgccggtga caaaccggag gaaggtgggg atgacgtcaa 91741 atcatcatgc cccttatgac ctgggctaca cacgtgctac aatggacaga acaaagggca 91801 gcgaaaccgc gaggttaagc caatcccaca aatctgttct cagttcggat cgcagtctgc 91861 aactcgactg cgtgaagctg gaatcgctag taatcgcgga tcagcatgcc gcggtgaata 91921 cgttcccggg ccttgtacac accgcccgtc acaccacgag agtttgtaac acccgaagtc 91981 ggtgaggtaa ccttttagga gccagccgcc gaaggtggga cagatgattg gggtgaagtc 92041 gtaacaaggt agccgtatcg gaaggtgcgg ctggatcacc tcctttctaa ggatatttta 92101 cggaatataa gaccttgggt cttataaaca gaacgttccc tgtcttgttt agttttgaag 92161 gatcattcct tcgaaacgtg ttctttgaaa actagataac agtagacatc acattcaagt 92221 aatacaagat atcacatagt gattcttttt aacggttaag ttagaaaggg cgcacggtgg 92281 atgccttggc actaggagcc gatgaaggac gggacgaaca ccgatatgct tcggggagct 92341 gtaagcaagc tttgatccgg agatttccga atggggaaac ccaccactcg taatggagtg 92401 gtatccatat ctgaattcat aggatatgag aaggcagacc cggggaactg aaacatctaa 92461 gtacccggag gaagagaaag caaatgcgat tccctgagta gcggcgagcg aaacgggatt 92521 agcccaaacc aagaggcttg cctcttgggg ttgtaggaca ctctgtacgg agttacaaag 92581 gaacgaggta gatgaagagg tctggaaagg cccgccatag gaggtaacag ccctgtagtc 92641 aaaacttcgt tctctcctga gtggatcctg agtacggcgg aacacgtgaa attccgtcgg 92701 aatccgggag gaccatctcc caaggctaaa tactccctag tgaccgatag tgaaccagta 92761 ccgtgaggga aaggtgaaaa gcaccccgga aggggagtga aagagatcct gaaaccgtgt 92821 gcctacaagt agtcagagcc cgttaacggg tgatggcgtg ccttttgtag aatgaaccgg 92881 cgagttacga tcccgtgcaa ggttaagcag aagatgcgga gccgcagcga aagcgagtct 92941 gaatagggcg catgagtacg tggtcgtaga cccgaaacca ggtgatctac ccatgtccag 93001 ggtgaagttc aggtaacact gaatggaggc ccgaacccac gcacgttgaa aagtgcgggg 93061 atgaggtgtg ggtaggggtg aaatgccaat cgaacctgga gatagctggt tctctccgaa 93121 atagctttag ggctagcctc aaggtaagag tcttggaggt agagcactga ttggactagg 93181 ggcccctacc gggttaccga attcagtcaa actccgaatg ccaatgactt atccttggga 93241 gtcagactgc gagtgataag atccgtagtc gaaagggaaa cagcccagac cgccagctaa 93301 ggtcccaaag tatacgttaa gtggaaaagg atgtggagtt gcttagacaa ccaggatgtt 93361 ggcttagaag cagccaccat ttaaagagtg cgtaatagct cactggtcga gtgactctgc 93421 gccgaaaatg taccggggct aaacgtatca ccgaagctgc ggactgttct tcgaacagtg 93481 gtaggagagc gttctaaggg ctgtgaagcc agaccggaag gactggtgga gcgcttagaa 93541 gtgagaatgc cggtatgagt agcgaaagag gggtgagaat cccctccacc gaatgcctaa 93601 ggtttcctga ggaaggctcg tccgctcagg gttagtcggg acctaagccg aggccgaaag 93661 gcgtaggcga tggacaacag gttgatattc ctgtaccacc tcctcaccat ttgagcaatg 93721 gggggacgca ggaggatagg gtaagcgcgg tattggatat ccgcgtccaa gcagttaggc 93781 tgggaaatag gcaaatccgt ttcccataag gctgagctgt gatggcgagc gaaatatagt 93841 agcgaagttc ctgattccac actgccaaga aaagcctcta gcgaggtgag aggtgcccgt 93901 accgcaaacc gacacaggta ggcgaggaga gaatcctaag gtgatcgaga gaactctcgt 93961 taaggaactc ggcaaaatga ccccgtaact tcgggagaag gggtgctctg ttagggtgca 94021 agcccgagag agccgcagtg aataggccca ggcgactgtt tagcaaaaac acaggtctct 94081 gcgaagccgt aaggcgaagt ataggggctg acgcctgccc ggtgctggaa ggttaagagg 94141 agcgcttagc gtaagcgaag gtgcgaattg aagccccagt aaacggcggc cgtaactata 94201 acggtcctaa ggtagcgaaa ttccttgtcg ggtaagttcc gacccgcacg aaaggcgcaa 94261 cgatctgggc actgtctcaa cgagagactc ggtgaaatta tagtacctgt gaagatgcag 94321 gttacccgcg acaggacgga aagaccccgt ggagctttac tgcagcctga tattgaatgt 94381 tggtacagct tgtacaggat aggtaggagc cttggaaacc ggagcgccag cttcggtgga 94441 ggcatcggtg ggatactacc ctggctgtat tgaccttcta acccgccgcc cttatcgggc 94501 ggggagacag tgtcaggtgg gcagtttgac tggggcggtc gcctcctaaa aggtaacgga 94561 ggcgcccaaa ggttccctca gaatggttgg aaatcattcg cagagtgtaa aggcacaagg 94621 gagcttgact gcgagaccta caagtcgagc agggacgaaa gtcgggctta gtgatccggt 94681 ggttccgcat ggaagggcca tcgctcaacg gataaaagct accccgggga taacaggctt 94741 atctccccca agagtccaca tcgacgggga ggtttggcac ctcgatgtcg gctcatcgca 94801 tcctggggct gtagtcggtc ccaagggttg ggctgttcgc ccattaaagc ggtacgcgag 94861 ctgggttcag aacgtcgtga gacagttcgg tccctatccg tcgcgggcgc aggaaatttg 94921 agaggagctg tccttagtac gagaggaccg ggatggacgc accgctggtg taccagttgt 94981 tctgccaagg gcatcgctgg gtagctatgt gcggacggga taagtgctga aagcatctaa 95041 gcatgaagcc cccctcaaga tgagatttcc cattccgcaa ggaagtaaga tccctgaaag 95101 atgatcaggt tgataggtct gaggtggaag tgtggcgaca catggagctg acagatacta 95161 atcgatcgag gacttaacca tatttttgaa tgatgtcaca tctgttatct agttttgaga 95221 gaacactctc aatttgtttg gtggcgatag cgaagaggtc acacccgttc ccataccgaa 95281 cacggaagtt aagctcttca gcgccgatgg tagtcggggg tttccccctg tgagagtagg 95341 acgccgccaa gcaattgcac gttagtgcaa ttatggagga ttagctcagc tgggagagca 95401 tctgccttac aagcagaggg tcggcggttc gagcccgtca tcctccacca ttatgccggt 95461 gtagctcaat tggtagagca actgacttgt aatcagtagg ttgggggttc aagtcctctt 95521 gccggcacca cttttatatg atataatact caagtctctt gtagaagagc cattagctca 95581 gttggtagag catctgactt ttaatcagag ggtcgaaggt tcgagtcctt catggctcac 95641 cattttacgc gggtgtggcg gaattggcag acgcgctaga cttaggatct agtgtcttta 95701 tgacgtgggg gttcaagtcc cttcacccgc attatatagg ataacagtta gaaaaactgg 95761 acatcctgtc tgcggaagta gttcagtggt agaacaccac cttgccaagg tgggggtcgc 95821 gggttcgaat cccgtcttcc gctccaacta taccatccac gccggggtgg tggaattggc 95881 agacacacag gacttaaaat cctgcggtag gtgactaccg tgccggttca agtccggccc 95941 tcggcattat gttttgcgcc cgtagctcaa ttggatagag cgtttgacta cggatcaaaa 96001 ggttaggggt tcgactcctc tcgggcgcgc catatctttt aatagaatag ataggaaatc 96061 gggaagtagc tcagcttggt agagcacatg gtttgggacc atggggtcgc aggttcgaat 96121 cctgtcttcc cgaccatttt tttatggggc cttagctcag ctgggagagc gcctgctttg 96181 cacgcaggag gtcagcggtt cgatcccgct aggctccacc aaaagttttt aaaaaagttg 96241 ttgactttga agaagtgacg ttgtatacta ataaagttgc tttaacaaag cggacaaaca 96301 aaatgatctt tgaaaactaa acaagacaaa acgtacctgt taattcagtt tttaaaaatc 96361 gcacagcgat gtgcgtagtc agtcaaacta ctttatcgga gagtttgatc ctggctcagg 96421 acgaacgctg gcggcgtgcc taatacatgc aagtcgagcg gacagatggg agcttgctcc 96481 ctgatgttag cggcggacgg gtgagtaaca cgtgggtaac ctgcctgtaa gactgggata 96541 actccgggaa accggggcta ataccggatg gttgtttgaa ccgcatggtt caaacataaa 96601 aggtggcttc ggctaccact tacagatgga cccgcggcgc attagctagt tggtgaggta 96661 acggctcacc aaggcaacga tgcgtagccg acctgagagg gtgatcggcc acactgggac 96721 tgagacacgg cccagactcc tacgggaggc agcagtaggg aatcttccgc aatggacgaa 96781 agtctgacgg agcaacgccg cgtgagtgat gaaggttttc ggatcgtaaa gctctgttgt 96841 tagggaagaa caagtaccgt tcgaataggg cggtaccttg acggtaccta accagaaagc 96901 cacggctaac tacgtgccag cagccgcggt aatacgtagg tggcaagcgt tgtccggaat 96961 tattgggcgt aaagggctcg caggcggttt cttaagtctg atgtgaaagc ccccggctca 97021 accggggagg gtcattggaa actggggaac ttgagtgcag aagaggagag tggaattcca 97081 cgtgtagcgg tgaaatgcgt agagatgtgg aggaacacca gtggcgaagg cgactctctg 97141 gtctgtaact gacgctgagg agcgaaagcg tggggagcga acaggattag ataccctggt 97201 agtccacgcc gtaaacgatg agtgctaagt gttagggggt ttccgcccct tagtgctgca 97261 gctaacgcat taagcactcc gcctggggag tacggtcgca agactgaaac tcaaaggaat 97321 tgacgggggc ccgcacaagc ggtggagcat gtggtttaat tcgaagcaac gcgaagaacc 97381 ttaccaggtc ttgacatcct ctgacaatcc tagagatagg acgtcccctt cgggggcaga 97441 gtgacaggtg gtgcatggtt gtcgtcagct cgtgtcgtga gatgttgggt taagtcccgc 97501 aacgagcgca acccttgatc ttagttgcca gcattcagtt gggcactcta aggtgactgc 97561 cggtgacaaa ccggaggaag gtggggatga cgtcaaatca tcatgcccct tatgacctgg 97621 gctacacacg tgctacaatg gacagaacaa agggcagcga aaccgcgagg ttaagccaat 97681 cccacaaatc tgttctcagt tcggatcgca gtctgcaact cgactgcgtg aagctggaat 97741 cgctagtaat cgcggatcag catgccgcgg tgaatacgtt cccgggcctt gtacacaccg 97801 cccgtcacac cacgagagtt tgtaacaccc gaagtcggtg aggtaacctt ttaggagcca 97861 gccgccgaag gtgggacaga tgattggggt gaagtcgtaa caaggtagcc gtatcggaag 97921 gtgcggctgg atcacctcct ttctaaggat attttacgga atataagacc ttgggtctta 97981 taaacagaac gttccctgtc ttgtttagtt ttgaaggatc attccttcga aacgtgttct 98041 ttgaaaacta gataacagta gacatcacat tcaagtaata caagatatca catagtgatt 98101 ctttttaacg gttaagttag aaagggcgca cggtggatgc cttggcacta ggagccgatg 98161 aaggacggga cgaacaccga tatgcttcgg ggagctgtaa gcaagctttg atccggagat 98221 ttccgaatgg ggaaacccac cactcgtaat ggagtggtat ccatatctga attcatagga 98281 tatgagaagg cagacccggg gaactgaaac atctaagtac ccggaggaag agaaagcaaa 98341 tgcgattccc tgagtagcgg cgagcgaaac gggatcagcc caaaccaaga ggcttgcctc 98401 ttggggttgt aggacactct gtacggagtt acaaaggaac gaggtagatg aagaggtctg 98461 gaaaggcccg ccataggagg taacagccct gtagtcaaaa cttcgttctc tcctgagtgg 98521 atcctgagta cggcggaaca cgtgaaattc cgtcggaatc cgggaggacc atctcccaag 98581 gctaaatact ccctagtgac cgatagtgaa ccagtaccgt gagggaaagg tgaaaagcac 98641 cccggaaggg gagtgaaaga gatcctgaaa ccgtgtgcct acaagtagtc agagcccgtt 98701 aacgggtgat ggcgtgcctt ttgtagaatg aaccggcgag ttacgatccc gtgcaaggtt 98761 aagcagaaga tgcggagccg cagcgaaagc gagtctgaat agggcgcatg agtacgtggt 98821 cgtagacccg aaaccaggtg atctacccat gtccagggtg aagttcaggt aacactgaat 98881 ggaggcccga acccacgcac gttgaaaagt gcggggatga ggtgtgggta ggggtgaaat 98941 gccaatcgaa cctggagata gctggttctc tccgaaatag ctttagggct agcctcaagg 99001 taagagtctt ggaggtagag cactgattgg actaggggcc cctaccgggt taccgaattc 99061 agtcaaactc cgaatgccaa tgacttatcc ttgggagtca gactgcgagt gataagatcc 99121 gtagtcgaaa gggaaacagc ccagaccgcc agctaaggtc ccaaagtata cgttaagtgg 99181 aaaaggatgt ggagttgctt agacaaccag gatgttggct tagaagcagc caccatttaa 99241 agagtgcgta atagctcact ggtcgagtga ctctgcgccg aaaatgtacc ggggctaaac 99301 gtatcaccga agctgcggac tgttcttcga acagtggtag gagagcgttc taagggctgt 99361 gaagccagac cggaaggact ggtggagcgc ttagaagtga gaatgccggt atgagtagcg 99421 aaagaggggt gagaatcccc tccaccgaat gcctaaggtt tcctgaggaa ggctcgtccg 99481 ctcagggtta gtcgggacct aagccgaggc cgaaaggcgt aggcgatgga caacaggttg 99541 atattcctgt accacctcct caccatttga gcaatggggg gacgcaggag gatagggtaa 99601 gcgcggtatt ggatatccgc gtccaagcag ttaggctggg aaataggcaa atccgtttcc 99661 cataaggctg agctgtgatg gcgagcgaaa tatagtagcg aagttcctga ttccacactg 99721 ccaagaaaag cctctagcga ggtgagaggt gcccgtaccg caaaccgaca caggtaggcg 99781 aggagagaat cctaaggtga tcgagagaac tctcgttaag gaactcggca aaatgacccc 99841 gtaacttcgg gagaaggggt gctctgttag ggtgcaagcc cgagagagcc gcagtgaata 99901 ggcccaggcg actgtttagc aaaaacacag gtctctgcga agccgtaagg cgaagtatag 99961 gggctgacgc ctgcccggtg ctggaaggtt aagaggagcg cttagcgtaa gcgaaggtgc 100021 gaattgaagc cccagtaaac ggcggccgta actataacgg tcctaaggta gcgaaattcc 100081 ttgtcgggta agttccgacc cgcacgaaag gcgcaacgat ctgggcactg tctcaacgag 100141 agactcggtg aaattatagt acctgtgaag atgcaggtta cccgcgacag gacggaaaga 100201 ccccgtggag ctttactgca gcctgatatt gaatgttggt acagcttgta caggataggt 100261 aggagccttg gaaaccggag cgccagcttt ggtggaggca tcggtgggat actaccctgg 100321 ctgtattgac cttctaaccc gccgccctta tcgggcgggg agacagtgtc aggtgggcag 100381 tttgactggg gcggtcgcct cctaaaaggt aacggaggcg cccaaaggtt ccctcagaat 100441 ggttggaaat cattcgcaga gtgtaaaggc acaagggagc ttgactgcga gacctacaag 100501 tcgagcaggg acgaaagtcg ggcttagtga tccggtggtt ccgcatggaa gggccatcgc 100561 tcaacggata aaagctaccc cggggataac aggcttatct cccccaagag tccacatcga 100621 cggggaggtt tggcacctcg atgtcggctc atcgcatcct ggggctgtag tcggtcccaa 100681 gggttgggct gttcgcccat taaagcggta cgcgagctgg gttcagaacg tcgtgagaca 100741 gttcggtccc tatccgtcgc gggcgcagga aatttgagag gagctgtcct tagtacgaga 100801 ggaccgggat ggacgcaccg ctggtgtacc agttgttctg ccaagggcat cgctgggtag 100861 ctatgtgcgg acgggataag tgctgaaagc atctaagcat gaagcccccc tcaagatgag 100921 atttcccatt ccgcaaggaa gtaagatccc tgaaagatga tcaggttgat aggtctgagg 100981 tggaagtgtg gcgacacatg gagctgacag atactaatcg atcgaggact taaccatatt 101041 tttgaatgat gtcacatctg ttatctagtt ttgagagaac actctcaatt tgtttggtgg 101101 cgatagcgaa gaggtcacac ccgttcccat accgaacacg gaagttaagc tcttcagcgc 101161 cgatggtagt cgggggtttc cccctgtgag agtaggacgc cgccaagcaa gcttaaaccc 101221 agctcaatga gctgggtttt ttgtattttg gtttattggt atcataaaat tccacttaac 101281 tgtataatat aataacttta taccgaattt taaatcagca atcaggtttt gtggaccggg 101341 aaaatggaaa taatgaagga tagagcgaga aagttgaaaa ttctcgagaa acggcttata 101401 gtaagattaa agtcaaatat agtcaaagtc agtaaaggag ggggttgagt gggacataat 101461 atttctgaca tcattgaaca atatttaaaa cgagtgttag atcaaaatgg caaggaaatt 101521 ttagagatta aacgaagtga aattgcagat aaatttcaat gcgttccttc ccaaataaat 101581 tatgtcatca acaccagatt tacaagcgaa agaggatata ttgttgagag caaacgcggg 101641 ggcggcggtt acatcagaat cattaaaatt aaaatgaaca atgaagttgt cctgatcaat 101701 aatataattt ctcaaattaa tacccatttg tctcaagcag cctctgatga cattatttta 101761 aggctattag aagacaaggt aatttcagaa agagaagcaa aaatgatggt cagcgtaatg 101821 gaccgctcag ttttacacat tgacttacct gaacgtgatg aattaagagc gagaatgatg 101881 aaggcaatgc tgacttcttt aaaattaaaa taagcgggtg aaaagattga tttgtcaaga 101941 gtgccacgag agaccagcca cttttcactt tacaaaggtt gttaacggag aaaaaataga 102001 agttcatatt tgtgaacaat gtgccaaaga aaatagtgat tcatatggta taagtgcaaa 102061 tcagggtttc tctattcata atttactttc gggtttactg aacatggatt cttcatttca 102121 aaatgcagga actcaaatgt tcagtcactc ggagcaaata tctgcttgtc cgaaatgcgg 102181 aatgactttt cagcaattca gaaaaattgg ccgttttgga tgttctgaat gttacaaaac 102241 atttcatagc aacattacac caatcctacg taaagtgcac agcggaaaca ctgtgcatgc 102301 aggtaagata ccgaaacgaa taggcggcaa tcttcatgtc agacggcaga ttgatatgct 102361 aaaaaaggaa ttagaatcct taatccatca agaagaattt gaaaatgcag ctcatgtaag 102421 agatcaaatt cgtttattag aacaatcact caaaagtaca gatagtgagg aggaacagga 102481 gtaatgtcgc taaagcattt tattcaggac gcactaagca gttggatgaa gcagaaagga 102541 cctgaaagtg acattgtact cagcagccgc atacgtttag caagaaactt tgagcatatt 102601 cggttcccta cgcggtattc caatgaagaa gcctcatcca tcatacagca atttgaagat 102661 cagttttcag agcaagaaat tcccggaatc ggcaaatttg ttttgattag aatgaatgat 102721 gcacagcctt tagaaaagcg tgtacttgtt gaaaaacatc taatcagccc gaatttgaca 102781 gagtctcctt ttggcggctg tttgctttct gaaaatgagg aagtaagcgt catgctaaat 102841 gaagaggacc atattagaat tcagtgtctt ttccctggat ttcagctttt agaagcaatg 102901 aaagccgcaa accaggtcga cgactggatt gaagaaaaag ttgattatgc attcaatgag 102961 caaagaggat acttaaccag ctgtcctaca aacgtaggta ctggtttaag ggcttcggtc 103021 atgatgcatc tgccggcgct ggttttaact aggcaaataa atcgaattat accggcaatt 103081 aatcaattag gcttagttgt tagaggaatt tatggggaag gcagcgaagc agtagggaat 103141 atctttcaaa tttcaaatca gatcacgctt ggtaagtcag agcaggatat tgtagaggat 103201 cttaacagtg ttgctgctca gttgattgaa caagaacgat ctgcccgaga agcgatttat 103261 caaacttcta aaatcgaact tgaggatcgg gtatatcggt catatggggt cttgtctaat 103321 tgccggatga tagaatcgaa agaaactgca aagtgccttt cagatgttcg gttaggcata 103381 gacttaggca taataaaagg actttcaagc aacatactta acgaacttat gattttgacg 103441 cagccagggt ttttacagca atactcggga ggcgctttgc gaccgaacga aagggacatt 103501 cgaagagcgg ctctcatcag agaacggctt cacttagaaa tgaatgggaa aagacaggag 103561 gatgaatcga tatgatgttt ggaagattta cagaacgagc tcaaaaagta ctggcgctag 103621 cacaggaaga agcacttcgg ttaggtcata ataacattgg cactgagcat attttattag 103681 gactggtaag agaaggagag ggcattgctg ctaaagctct tcaagcgctt ggactcggtt 103741 cagaaaaaat tcagaaagaa gtagaaagtt tgatcgggcg cgggcaggaa atgtctcaaa 103801 cgattcatta tactcctaga gctaaaaaag tcattgagct ttcaatggat gaggcaagaa 103861 aactcggtca ttcttatgtg ggaacagaac atattcttct tggtctgatt cgtgaaggag 103921 aaggtgttgc tgcgagagtt ctgaataatc tcggtgtcag cttaaataaa gcaagacagc 103981 aggtgctcca gcttctagga agtaatgaaa caggatcatc agcggcagga acaaacagca 104041 atgcgaatac gcctacgctt gacagcttgg caagagactt aactgctatt gcgaaggaag 104101 acagccttga ccctgtaatc ggcagaagca aggagatcca gcgtgtcatt gaagtgttaa 104161 gccgcagaac gaaaaacaac cctgttctca ttggggaacc aggtgtaggt aaaacggcta 104221 tcgcagaagg tttggcacag caaattatca ataatgaagt acccgaaatt ttgcgtgata 104281 aacgtgtgat gacattagac atgggaacag ttgttgccgg cacaaaatac cgcggagaat 104341 ttgaggatcg cctgaagaag gtcatggatg aaattcgcca ggcaggaaat atcattctat 104401 tcatcgatga gctccataca ttaatcgggg caggcggagc agaaggtgct attgatgcat 104461 ctaatatttt aaaaccttca cttgctcgtg gcgaactcca atgtattggt gcaacgactc 104521 ttgatgagta ccgtaaatat attgaaaaag atgcagcact ggaacgccgt tttcagccga 104581 ttcaggttga tcagccatct gtagatgaaa gtattcaaat tttacaaggt ctgcgtgaca 104641 gatacgaagc ccaccaccgc gtttctatca ctgatgatgc cattgaagct gcggttaagc 104701 tttctgacag atatatttct gaccgcttcc ttccggataa agcaattgac ttgatcgatg 104761 aagcgggttc aaaggtgaga ctgcgctcat ttacaacgcc tcctaactta aaagagcttg 104821 agcagaagct tgatgaggtt cgtaaagaga aggatgcggc agtgcaaagc caagagtttg 104881 aaaaagctgc ttccttgcgt gatactgaac aacgcctgcg cgagcaagta gaggatacga 104941 agaaatcatg gaaagagaag caagggcagg aaaactcaga ggttactgtg gatgatattg 105001 cgatggttgt atccagctgg accggtgtgc ctgtatctaa aatcgcccaa actgaaactg 105061 ataagcttct caatatggaa aacattcttc actcccgtgt catcggccag gatgaagcag 105121 ttgtagcggt tgcaaaagcc gtcagacgtg caagagcagg attgaaagat cctaaacgcc 105181 caatcggctc attcattttc ttaggcccta caggtgtagg taaaacagaa cttgcacgag 105241 cacttgctga atccattttt ggcgatgaag aatccatgat cagaattgat atgtctgaat 105301 acatggaaaa acattcaact tcaagacttg ttggttcacc tccgggttat gtgggatatg 105361 atgaaggcgg tcaattgaca gagaaagtca gaagaaaacc ttactctgtc gtgcttcttg 105421 atgagatcga gaaagcgcac cctgatgtct tcaatatcct tctgcaagtt cttgaagacg 105481 gacgattgac tgattctaaa ggacgcacag tcgatttccg caataccatt ctgatcatga 105541 catcaaacgt cggagcaagt gagctaaaac gcaataaata tgtcggcttt aacgttcagg 105601 atgaaactca aaatcataaa gacatgaaag ataaagtgat gggtgaatta aaacgagcgt 105661 tcagacctga gttcatcaac cgtattgatg aaatcattgt cttccattca cttgagaaaa 105721 aacatctcac tgagattgtg tcattaatgt ctgatcaatt aacgaaacgc ctgaaagaac 105781 aagatctttc tatcgaattg acagatgctg caaaagcgaa agtcgcggaa gagggcgttg 105841 acctggaata cggtgcccgt ccgttaagaa gagcgatcca aaaacatgtc gaggatcgtt 105901 tatctgaaga actcctcaga ggaaatattc ataaaggaca gcatattgtt cttgatgtag 105961 aagatggcga atttgtcgta aaaacgactg ctaaaacgaa ttaatataga agacggaaat 106021 gaggcataca gcatgtaagt gtatgcctca ctttcatatc aagaaataga acaagggaga 106081 ggtcttacac tatatatggc taaaacaaaa tcgaagttca tctgccaatc ctgcggctac 106141 gagtctccaa aatggatggg gaaatgtccg ggctgtggtg cttggaatac aatggtggaa 106201 gaaatgatta aaaaagcacc ggccaatcgg agagcggctt tttctcattc tgttcaaact 106261 gtacagaaac cttcacctat tacatcaatc gaaacatcag aagaaccccg cgtcaaaacc 106321 cagcttggcg agtttaacag agtactcggc ggaggtgtcg ttaaaggctc cctcgtttta 106381 attggcggtg atcctggtat cggaaagtca acgctattac tgcaggtttc cgctcaatta 106441 tcaggctcat caaacagtgt cctgtatatt tcgggagaag aatctgtaaa gcaaacgaag 106501 ctgcgagcag accgtctcgg cattaataat ccgtcactgc atgttttatc tgaaaccgat 106561 atggagtata tttcgtctgc tatacaagag atgaatccat cgtttgtcgt tgttgactct 106621 attcaaacgg tttaccaaag cgatattaca tctgctccag gcagtgtgtc acaggtcaga 106681 gaatgtaccg ctgagctgat gaaaattgca aaaacaaaag gtattccgat ttttatcgta 106741 gggcacgtga cgaaagaagg gtctattgca ggtccgagac tgttggagca tatggttgac 106801 actgttttat attttgaagg agaacgccac catactttcc gtattttgcg ggctgtaaaa 106861 aaccgtttcg gatctacaaa cgaaatgggc attttcgaaa tgcgggaaga ggggctcact 106921 gaggttttga atccttcgga aattttctta gaagaacgct ctgctggttc cgcaggctcg 106981 agtatcactg cctctatgga gggcactaga ccgattctcg ttgaaattca ggcactcatc 107041 tcgccaacaa gttttggcaa cccaaggcgt atggcaacgg gaatagacca taacagggtt 107101 tctctgttaa tggctgtgtt agaaaaaaga gttggactgc tgctgcaaaa tcaggatgct 107161 tatttgaaag tggctggcgg cgttaagctt gatgaaccgg caattgatct tgcgattgtg 107221 attagtattg catcaagctt tagagacaca cctccaaatc ctgcagattg ttttattgga 107281 gaagtgggat taaccggaga agtccggcgg gtttcaagaa ttgaacagcg tgtgaaagaa 107341 gcggcaaagc ttggttttaa acgcatgatc atacccgcgg caaatctgga tggatggaca 107401 aaaccaaaag ggattgaggt tatcggagta gcaaatgttg cagaagcgct tcgtacttca 107461 ttaggaggat aatagatgga aaaagagaaa aaaggggcga aacacgagtt agacctgtca 107521 tctatattgc agtttgttgc tccgggtaca ccgctcagag cggggatgga aaacgtcttg 107581 agagcaaata caggcggtct gattgttgtt ggatataatg ataaagtaaa agaagtggtg 107641 gacggcggct ttcacataaa cacggctttt tctccggcgc atttatatga gctggctaaa 107701 atggatggag cgatcatttt aagtgattct ggtcaaaaga tcctatacgc gaatactcag 107761 ctgatgccgg atgccacaat ttcttcatca gaaacaggaa tgcggcacag aactgccgaa 107821 agagtagcta agcaaactgg ctgtcttgta atcgccattt ctgaaagaag aaatgtcata 107881 acgttatatc aggaaaacat gaagtataca ctaaaagaca taggatttat tttaaccaag 107941 gcgaaccaag ccattcaaac acttgaaaaa tataagacaa tcctcgataa aacgattaat 108001 gcactgaacg cgttagagtt tgaggaactt gttaccttca gtgatgtctt gtctgtcatg 108061 catcgttatg aaatggtact gagaatcaaa aacgaaatta atatgtatat caaagagctg 108121 gggacagaag ggcatctgat caaactgcaa gtcattgaat tgattacgga tatggaagaa 108181 gaggccgctt tatttattaa ggactatgta aaagaaaaga ttaaagatcc gtttgttctc 108241 ttgaaggagc tgcaggatat gtccagttat gatctgctgg atgattccat tgtgtataag 108301 cttctcggtt accctgcttc tactaatctt gatgattatg tattgccgag aggatacagg 108361 ctgttaaata agataccgcg tcttccgatg ccgattgttg aaaatgttgt agaagcattt 108421 ggagtcctgc caaggattat tgaggcgagt gcagaagaat tagatgaagt agagggaatc 108481 ggtgaagtac gagcccaaaa aatcaaaaaa ggattaaaac gcctgcaaga gaagcattat 108541 ttagacagac aactgtgatt tcggttaaaa ccttatgaat acgggtatat taatgttggt 108601 ttttgtttat tctgatattc gtaggatgca taagactttg tgaaattaaa atgttaaaaa 108661 aggaggtggg ggtatgttaa aacgaatagt tcaggcgttc ttcattattt ttggcggcgt 108721 tgttggtata tttttgatac ctgaattgtt tgtactgtta aatatacagg acataccttt 108781 aataacaaac gcatatacgt ctgcggcaat aggagcaatt atcttttttc tcatcagtat 108841 atggggtaca gaatacgttg tgaactgggt gaagtggata gaggattcat tgttaaaagc 108901 gccggttcca gatttgttat ttggaagtct tggcttagtt tttggactta taattgctta 108961 tcttatcgta aatgttattc ctttagacaa tataccttac cgcatattca gcacaataat 109021 tcctgtattt ttggctttct tcctcggtta tctcggcttc caggtgggct ttaagaaaaa 109081 ggatgaattg atcagcctgt tttccatttc cgccagaatg caaaagaaaa aaggaacagc 109141 tgatgaagaa catgaggttc aagacaagaa gctgaaaatt ttggacacta gtgttattat 109201 tgatgggaga atagcagata tttgtcagac tggtttttta gagggagtta tcgtgattcc 109261 gcagtttgtc cttgaggaat tgcagcatat tgcagactct tcagatgttt taaaacgaaa 109321 cagaggacgc cgcggtcttg atatcctgaa ccgcattcag aaagaattag acattgaagt 109381 tgaaatttac gaaggcgact ttgaagatat tcaggaggtt gacagcaagc tcgtcaaact 109441 tgctaagctg acatccgggg tcgttgtgac gaatgatttt aatttaaata aagtgtgcga 109501 gcttcagaag gtagcagtat taaacattaa tgaccttgcc aatgcggtta agcctgttgt 109561 gcttcctggc gaggaaatga atgttcaggt cattaaggac gggaaagagc ataatcaggg 109621 agttgcctac ttggatgacg gtacgatgat tgtcgttgaa gaaggacgga attatatcgg 109681 caagcatatt gatgtactcg tcacaagtgt gctgcagaca gcagcgggac gaatgatttt 109741 tgcgaagcct aagctgttgg agaaggcgct gtaaagggag aagaaacaat gagttatgat 109801 gtggtgattc ctgcagccgg acagggaaag cggatgaagg cagggagaaa taaactgttc 109861 attgagctga agggagaccc ggtgatcata cacacgttaa gagtgtttga cagccaccgg 109921 cagtgcgata aaatcatttt ggtgattaac gagcaggagc gggagcactt tcagcaattg 109981 ctgtccgatt acccgtttca aacttcaatt gagcttgttg caggcggaga tgagcgacag 110041 cacagtgtgt ataaggggct gaaagccgta aagcaggaaa agattgtcct tgtacatgac 110101 ggtgcccgtc catttataaa acatgaacaa attgacgaac tgatcgcaga ggcggaacag 110161 acaggagcgg ccatccttgc tgttccggta aaagatacga ttaaacgcgt tcaagattta 110221 caagtcagtg agacgattga acgttcaagc ttgtgggctg tccaaacgcc acaagctttt 110281 cgtctttctt tattgatgaa ggctcacgct gaggccgagc gcaagggatt tttagggacg 110341 gatgacgcca gcctcgttga acagatggag ggcggttcgg tccgtgttgt agaaggcagc 110401 tatacaaata ttaagctgac gacgccagac gatttgacgt cagctgaagc tatcatggaa 110461 tcagaaagtg ggaataaaca tgtttagaat tggacaagga tttgatgtgc atcaattagt 110521 ggagggccgt cctctcatta ttggcggaat tgaaatcccg tacgaaaaag ggctgcttgg 110581 ccattctgat gcagacgtat tgttgcatac cgtcgctgac gcctgcctgg gagctgtggg 110641 tgaaggagac ataggcaagc attttcctga cacagatccc gagttcaagg acgcagattc 110701 tttcaaatta cttcagcatg tctggggaat cgtgaaacag aaggggtatg tccttgggaa 110761 cattgattgc accatcatag cgcaaaagcc gaagatgctg ccgtacatag aagatatgag 110821 aaaaagaatt gctgaaggcc ttgaggcaga tgtttctcaa gtaaatgtaa aagcaacaac 110881 gacagaaaag cttggattta caggccgggc ggaaggaata gcggctcagg cgacagtact 110941 gatacaaaaa ggctaacttg ttttgatgcc gggtctattt ggtggtagaa tagattcata 111001 catttttgcc tgaggccata catgacatga aaggaagtat ttgaaaatgg gaaacgaagt 111061 acgcgtccgt tatgcaccga gtccaaccgg acatttgcat attggaaatg ccagaacggc 111121 gctttttaat tatttatttg cccgcaatca aggcggtaag tttatcattc gagttgagga 111181 tactgataaa aagcgcaata ttgagggcgg agaacaaagc cagctgaatt atctgaagtg 111241 gctaggtatt gactgggatg agagtgtgga tgtcggagga gagtacggtc cataccgtca 111301 gtcagagcgt aacgatatct ataaagtgta ctatgaagag cttcttgaaa aagggcttgc 111361 ttataaatgt tactgtacgg aagaagagct tgaaaaagag cgtgaagaac agattgcccg 111421 cggagaaatg cctcgttatt ccggaaaaca cagagacctg actcaggaag aacaggagaa 111481 atttatcgcc gaaggcagaa aaccaagtat tcgtttccgt gtgccggaag gaaaagtcat 111541 cgccttcaac gacatcgtaa aaggcgaaat ttcttttgaa tcagatggca tcggcgactt 111601 cgttattgtg aaaaaggacg gaacgcctac ttataacttc gcggtagcta ttgatgacta 111661 cttaatgaaa atgacacacg tgctgcgcgg tgaggatcat atttctaaca caccgaaaca 111721 gattatgatc tatcaagcat tcgggtggga tattcctcag ttcggacaca tgacgctgat 111781 tgtaaacgaa agccgtaaaa agctcagcaa acgtgatgaa tccattattc aattcatcga 111841 gcagtacaaa gagcttggct acctgccaga agcgctgttc aactttatcg gcttgttagg 111901 ctggtcaccg gttggagaag aagagctttt cacaaaagag cagtttattg aaatttttga 111961 tgtaaatcgt ttatctaaat caccagcttt gtttgatatg cataagctaa aatgggttaa 112021 caaccaatat gtgaagaagc tggatcttga tcaggttgtt gaactgacgc ttccgcattt 112081 gcaaaaagcc ggcaaagttg gcactgagct ttctgctgaa gaacaagaat gggttcgtaa 112141 actgatttcc ctgtatcatg agcaattaag ctacggtgcg gaaattgttg agctgactga 112201 tttgttcttt acggatgaga tcgagtataa tcaagaagcg aaagctgttc tggaagaaga 112261 acaggttcct gaagtgctca gcacattcgc agcgaagctt gaagagcttg aggagttcac 112321 tccggataat atcaaagcat cgatcaaagc agtgcagaaa gaaactggcc ataaagggaa 112381 aaaactgttt atgccgattc gtgttgctgt aacagggcaa actcacggtc cggaactgcc 112441 gcaatcaatt gaattgatcg gtaaagagac tgcaattcag cgtttaaaga atatctaaat 112501 aaatgattgt tgacagggaa gagtataaag ctttaggcca ttacagaaag gatcttcatt 112561 ggctgagaga gatccatgag ccgggtttta gaagtgcgcc cttaagacct ttgaagaacg 112621 ttttttgaaa tcagtattca aaggcggccg ccgccgttac aggctgaagt tgggagagca 112681 gaagtctgct tttcaaacag agtggaaccg cgcggttaaa gcgtctctgt catgtttaca 112741 tgcagagacg ctttttttat tgggtagagg aaatcagata gagaaacggg gggaagcatg 112801 tgttttttag aatgctcaaa gaagacattg atactgtgtt cgatcaagat cccgcagcaa 112861 gaagctattt tgaagtgatt ttaacttatt ccggtttaca tgctatatgg gcgcatcgga 112921 ttgcacatgc tttatataaa cgaaaatttt atttccttgc acgccttata tctcaagtaa 112981 gccgattttt taccgggata gaaatccacc ccggcgctac aatcgggaga agatttttca 113041 tagaccacgg catgggggtt gtcattgggg agacatgtga aatcggcaat aacgtaaccg 113101 tttttcaggg ggttaccctc gggggaacgg gaaaagaaaa gggaaaaagg cacccaacga 113161 ttaaagatga cgcattgata gccacaggtg ctaaagtgct cggttctatt acggtcggtg 113221 aaggctcaaa gattggcgct ggttcagtag tgctgcatga tgttcctgat ttttcaacag 113281 ttgtcggtat ccctggacgg gtcgttgtac aaaatggcaa gaaagtaaga cgcgatttaa 113341 accatcagga tttgcccgat ccagttgctg accgctttaa gtctttggaa cagcagattt 113401 tagagctgaa ggcagaactt gaagacagaa aagaaaggat caatcaaaaa tgacaatcac 113461 actttataat acattgacta gacagaagga aacattcgtt cctcttgaag agggaaaagt 113521 gaaaatgtat gtatgcggac ccacggttta caattacatt catatcggga acgcgcgtcc 113581 ggcaatcgtt tacgatacgg ttcgaaacta tttagagtat aaaggctatg atgtgcagta 113641 tgtctctaac ttcacagacg tagacgataa attaattaaa gcggcaaatg aactcggtga 113701 ggatgtaccc accatttcag agcgttttat taaagcatac tttgaagacg taggtgcgct 113761 cggctgccga aaagccgacc ttcatccgcg agtaatggag aacatggatg ccattatcga 113821 attcgtagat cagctcgtga aaaagggcta cgcatatgaa tcagaaggtg acgtatattt 113881 caaaaccaga gcatttgaag ggtacggaaa gctttctcag caatcaatcg atgaactaag 113941 atcaggtgca cgcatccggg tcggcgagaa aaaagaagat gctcttgatt tcgcactgtg 114001 gaaagcggca aaagaaggag aaatctcttg ggatagccct tgggggaaag ggcgtccggg 114061 ctggcacatt gaatgctcag caatggtgaa aaagtatctc ggtgaccaga ttgatatcca 114121 tgcgggcgga caggatttaa cattccctca ccatgaaaac gaaattgcgc aatctgaggc 114181 gctgacaggc aaaacgtttg cgaagtactg gcttcataat ggttatatca atattgataa 114241 tgaaaaaatg tcaaaatcac taggcaactt tgtgcttgtg catgacatca ttaaacagca 114301 tgatccgcag cttttgagat tctttatgct atctgttcat tatcgccatc cgattaacta 114361 ttcagaagag cttctggaga atacgaaaag cgcgttcagc cgtttaaaaa cagcgtacag 114421 caatcttcag caccgtctga acagcagtac gaatttaacc gaagatgacg atcaatggct 114481 tgaaaaggtt gaagaacacc gcaaagcatt cgaagaagag atggacgatg attttaatac 114541 ggcgaatgcc atttcagtct tgtttgactt agcgaaacac gccaattatt atcttcagaa 114601 agatcatacg gctgatcatg tgattacggc gtttattgag atgtttgacc gcattgtttc 114661 tgtcctcggt ttttcgttgg gtgagcagga acttctcgat caagagattg aagacttaat 114721 cgaaaagcga aatgaagcgc gccggaatcg cgattttgca ttgtcagacc agatccgcga 114781 ccagctgaaa agcatgaata tcattcttga agatacggct caaggcactc gctggaaacg 114841 gggagaataa cagatgcttg aatttgatac gataaaagat tctaagcagc ttaacggtct 114901 tgcgcttgct tatataggtg atgccatttt tgaagtgtat gtcaggcatc acctgcttaa 114961 gcagggcttt accaaaccaa atgatcttca taagaaatca agccggattg tttcagcaaa 115021 gtcacaggct gagatcctat tttttctgca gaatcaatca ttttttacgg aagaagagga 115081 agcggtgctg aaaagaggca gaaatgccaa gtcagggaca acacctaaaa atacagatgt 115141 tcagacgtac cgctacagta cagcatttga agcgcttctg ggctaccttt ttctagagaa 115201 aaaagaggaa cgacttagtc agctcgtagc cgaagctata caattcggga cgtcagggag 115261 gaaaacaaat gagtcagcaa catgattacg tcatagggaa aaatgcagtg atcgagacgt 115321 taaaatctga tcggaagctg tataagctgt ggatggcgga aaacaccgta aagggacaag 115381 cacagcaagt gattgagctt gccaaaaagc agggaatcac gattcaatac gtcccgagaa 115441 aaaaactcga tcaaatggtg acaggacagc atcagggcgt agtggcacag gttgcagcgt 115501 atgaatatgc agaactggac gatttatata aagcagccga agaaaaaaat gaacagcctt 115561 tcttcctcat tctggacgag cttgaagacc ctcataatct tggttccatt atgaggacag 115621 cagatgcggt cggcgctcat ggcatcgtca ttccaaaacg gagagctgtc gggctgacaa 115681 caacagtggc aaaagcttca acaggagcaa ttgagcacat tcctgtagca agagtcacca 115741 atttggcacg gacgttagaa gagatgaaag agcggggaat ctgggttgtc ggaacggatg 115801 cgtccgcgcg tgaggatttc cgtaatatgg acggcaatat gcctttggct ctagtcatcg 115861 gaagtgaagg aaaagggatg ggccgccttg tgaaggaaaa gtgcgatttt ctcattaaac 115921 tcccgatggc cggaaaggta acttcactaa atgcatctgt cgcggctggt cttttgatgt 115981 atgaagtcta ccggaaacga aaccctgtgg gagaataaag acccatggat atcctgttag 116041 tagacgggta caacatgatt ggagcctggc cgcagctgaa ggatttaaaa gcgaacagtt 116101 ttgaagaggc gagagacgta ctgattcaga aaatggcgga atatcaatcg tatacaggaa 116161 acagggttat tgttgttttt gacgcgcatc tcgtaaaagg gcttgagaaa aaacagacca 116221 accatagagt tgaagtaatt tttacaaaag aaaatgagac ggctgatgag cggatagaaa 116281 agctcgctca ggctttgaat aatattgcga ctcaaattca cgttgcgacc tctgactata 116341 ctgagcagtg ggcgattttc ggacaggggg cattgcggaa atcggcccgg gagcttctga 116401 gagaggtaga aacgattgaa aggcgaatag agagacgggt aagaaaaatc acttccgaaa 116461 agccggcggg taaaattgct ttatcggaag aggttttgaa aacgtttgaa aagtggaggc 116521 ggggagactt agattaagtt gacgcttttt tgcccaatac tgtataatat ttctatctac 116581 gtgcgccggg gggatcggag tgaatctaca gaacaacaag ggaaaattca acaaagagca 116641 gttttgccag ttggaggacg agcaggtcat tgaaaaggtt catgttgggg acagtgatgc 116701 gttagattac ttgattacga agtaccgaaa ctttgttcgg gcaaaagcaa gatcctattt 116761 cttaataggg gcggacagag aggatattgt tcaggaaggc atgataggcc tctataagtc 116821 tattcgtgac ttcaaagagg acaagcttac ctcattcaaa gcttttgcag aattatgtat 116881 tacccgccaa attattaccg caataaagac agctactcgc cagaaacaca ttcctttgaa 116941 ttcctacgcc tcattagata aaccgatctt tgatgaagaa tcagaccgaa cgctgctgga 117001 tgtcatttca ggagcgaaaa ccttaaatcc tgaggaaatg atcattaatc aggaagaatt 117061 tgatgatatt gaaatgaaaa tgggagaact attaagtgat ttagagagaa aagtactcgt 117121 cttatatctc gacgggagaa gttaccaaga gatttctgat gaactgaacc gacatgtgaa 117181 atcgatcgac aatgcccttc agcgtgtgaa acgcaagctg gagaagtact tggaaattcg 117241 cgaaatcagt ttgtaatagg aatttatgct atattgacag tatttttctg actatgatat 117301 gttactaaag ataagaacta atgtctattt agaaaaaggt gtaatgacat gagaaaaaag 117361 attacgttag catgcaagac atgcggaaac cgtaattata cgacaatgaa gagctctgca 117421 tcagcggctg agcgattaga agtaaagaaa tactgcagta cttgcaattc acatacagct 117481 catcttgaaa caaaatagtt tttgcgcttt taaattgtgg aggtctttta catgcgtatt 117541 atgaaattct ttaaagatgt tgggaaagaa atgaaaaagg taagctggcc taaaggaaaa 117601 gagttaacgc gttataccat tacggtaatt tcaacagtta tcttttttgt tatctttttt 117661 gccctccttg acacaggaat ttctcaatta attcgtttaa tagttgaata atgatcagca 117721 atacgtgcta taatagatca taatattact tgccaaaacc cgttcagcgg gttttttatt 117781 gtggcttaaa atgaaagtta tcataggctt gccgcctatt ttttgaagcg ttatggtaat 117841 tcactaaaac caaatgcggg gagggaagga ctggacagtc ctgaatagaa tggaaaagaa 117901 ttggtatgtt gttcacacgt actctggtta tgagaataaa gtaaaagcca acttggaaaa 117961 gcgtgttgaa tcaatgggga tgcaggataa aattttccgt gtagtcgtac ccgaagaaga 118021 agaaacggat atcaaaaacg gcaagaaaaa agtcgtgaaa aagaaagtat tccctggtta 118081 tgtgcttgtt gaaattgtaa tgacagacga ctcttggtat gtcgtccgca acacgccggg 118141 cgttactgga ttcgtaggat ctgccgggtc aggttcaaaa ccgacgccgc ttcttccggg 118201 ggaagcagaa accattctga agagaatggg catggatgaa cgaaaaactg atattgactt 118261 tgaactgaaa gagacagtga aagtaataga cggacctttt gctaacttta caggatcaat 118321 tgaagagatt gattatgata aaagcaaggt caaagttttc gttaatatgt ttggccgtga 118381 aacgccggtt gagctggaat ttacccaaat cgataaattg taatgtgaaa aaacttgaaa 118441 ttgctatata taaatgataa tatagcaaag gtacgtcttg gacttatcca aggcaactag 118501 catgatattt cgtcattcat ataaagaatg aaaccttgag tgggagggtt taccctatta 118561 ccacatcacg gacttaagga ggtgtgtctc gtggctaaaa aagtagttaa agttgtaaaa 118621 ttgcaaattc ctgctggaaa agctaaccca gcaccaccag ttggacctgc acttggtcaa 118681 gccggtgtta acatcatggg attctgtaag gagtttaacg ctcgtacagc tgaccaagct 118741 ggtttaatca ttcctgttga aatttcggtt tacgaagacc gttcatttac atttattaca 118801 aaaactccac ctgctgcagt attgcttaaa aaagcagctg gaattgagtc tggttctggt 118861 gaaccaaacc gtaataaagt ggcaaccgtt aagcgcgata aagtacgcga aatcgctgaa 118921 acgaaaatgc ctgacttaaa cgcagcagac gttgaagcgg caatgcgcat ggttgaaggt 118981 actgcccgca gtatgggtat tgtaatcgag gattaatttg tttcttgtcg ggttgcgagt 119041 tttaacaagt tcgcaaccct tattcgtggg aggttattcc gctataacca cataaggagg 119101 aaattttaaa atggctaaaa aaggtaaaaa gtacgttgaa gctgctaagc ttgtagaccg 119161 ttctaaagct tacgacgtct ctgaagcagt agctctcgtt aaaaaaacaa acacagctaa 119221 attcgacgct acagttgaag tggctttccg tttaggggtt gaccctcgta aaaacgacca 119281 gcaaatccgt ggagcagttg tgcttccaaa cggaactggt aaaactcagc gcgttctcgt 119341 tttcgcaaaa ggcgaaaaag cgaaagaagc tgaagctgct ggtgcagatt tcgtaggcga 119401 tactgactac atcaacaaaa ttcaacaagg ctggttcgat ttcgatgtta tcgtagctac 119461 acctgacatg atgggtgaag ttggtaaaat cggtcgtgta cttggaccaa aaggtttaat 119521 gccgaaccct aaaactggta cagttacttt cgaagttgaa aaagctatcg gcgaaatcaa 119581 agctggtaaa gttgaatacc gcgttgataa agctggaaac attcatgttc ctatcggtaa 119641 agtttctttc gaggatgaaa aacttgttga gaacttcaca acaatgtacg atacaatcct 119701 taaagctaaa cctgctgcag ctaaaggcgt ttacgtgaaa aacgttgctg taacttctac 119761 tatgggacct ggtgtcaaag tagactcttc aacttttaac gtaaaataat attgacatga 119821 catcaacatt ctgatattat tcaaaatgtt gtaaaataga atatcattta taccgtagac 119881 agtaggggcc taaccgctta attatcctac cgaggtgtat attatcacag ctattacgtt 119941 acgtatgctt gtatatacag cctccatgtc tcatggaggc tttttatatg gaatccgtcg 120001 tctcagtcgt gatcacctaa cggtataagt gttacacaag aatctacagg aggtgtaacc 120061 atgagcagcg caattgaaac aaaaaaagtt gttgttgaag aaattgcttc taaactgaaa 120121 gaaagtaaat caacgatcat cgttgactat cgcggactta acgtttctga agtaactgaa 120181 cttcgtaaac agcttcgcga agctaacgtt gagttcaaag tttacaaaaa tacgatgact 120241 cgccgtgcgg ttgaacaagc tgagcttaat ggtttgaatg atttcttaac tggaccgaac 120301 gcgatcgcat tcagcactga agatgttgtc gctccggcta aagttcttaa tgacttcgct 120361 aaaaatcacg aagctcttga aatcaaagct ggcgttatcg aaggtaaagt ttctactgtt 120421 gaagaagtga aagctcttgc tgaacttcca tcacgcgaag gcttgctttc tatgttgctt 120481 agcgtacttc aagctccagt tcgcaacctt gctcttgctg caaaagctgt ggcagaacaa 120541 aaggaagaac aaggcgctta atctaatcag tttttcataa attaaaacaa aatggaggaa 120601 ttacaaatgg ctttaaatat cgaagaaatc attgcttccg ttaaagaagc aactgtactt 120661 gaattgaacg acctagtaaa agcaatcgaa gaagaatttg gcgtaactgc tgctgctcct 120721 gtagctgtag ctggcggagc tgctgctggc ggagctgctg aagagcaaag cgaattcgat 120781 cttatccttg ctggtgcagg atctcaaaaa atcaaagtta tcaaagttgt acgtgaaatc 120841 actggtcttg gcttgaaaga agctaaagag cttgttgaca acactccaaa accacttaaa 120901 gaaggtattg ctaaagaaga agctgaagag cttaaagcta aacttgaaga agttggcgct 120961 tctgtagaag ttaagtaatc ttcacttacc tgtaggggaa gctcgctttt atgaggcgag 121021 ctttttcttt gccattcttt aagccatgaa aaaaggaggt tctaataatg agtgagcact 121081 attattcaga aaaaccttca gtaaaaagca acaagcaaac ctggtctttt aggcttcgga 121141 ataaagattt cacgtttacc agcgacagcg gggttttttc taaaaaagaa gttgatttcg 121201 gctcccgcct gctgattgat tcttttgaag agcctgaggt tgagggcggc attttagatg 121261 taggctgcgg atacggcccg attggtttat cgctcgccag cgactttaaa gaccggacca 121321 tccacatgat tgacgttaat gagagagccg tagaactatc aaatgaaaat gcggaacaga 121381 acggaataac aaacgttaag atttatcaaa gcgatttgtt ttcaaacgtt gattctgctc 121441 aaacatttgc ttctattctt acaaatcccc caatccgagc cggaaaaaaa gttgtccatg 121501 ctatctttga gaaaagcgct gaacacttaa aagcttcagg tgaattgtgg atcgtcatac 121561 agaaaaagca aggcgcgcct tctgccattg aaaagctcga ggaactgttc gatgaagttt 121621 ccgtcgttca aaaaaagaaa ggctattata tcataaaagc aaaaaaagtt tgactcggta 121681 ttttaactat gttaatattg taaaatgcca atgtatatat tttgcttgat atgatgaatt 121741 gtcaatatct atgtataaat tatacaagta tggaaatgct aataaaatcg gtatttgttt 121801 ttggatgtgg ttttcttaat tagaaaccct tttttctttt gtcttgtaaa agtattttct 121861 ttctttggaa gaaatgctta ttacacatat aatacgcatg atttgagggg tgaatcagtt 121921 gacaggtcaa ctagttcagt atggacgaca ccgccagcgc agaagctatg ctcgcattag 121981 cgaagtgtta gaattaccaa atctcattga aattcaaacc tcttcttatc agtggtttct 122041 tgatgagggt cttagagaga tgtttcaaga catatcacca attgaggatt tcactggtaa 122101 cctctctctt gagttcattg attatagttt aggtgagcct aaatatcctg tagaggaatc 122161 aaaagaacgt gatgtgactt actcagctcc gctaagagtg aaggttcgtt taattaacaa 122221 agaaactgga gaggtaaaag accaagatgt cttcatgggt gatttcccta ttatgacaga 122281 tacaggtact tttatcatta acggtgcgga acgtgttatc gtttcccagc ttgttcggtc 122341 tccaagtgta tatttcagtg gtaaagtaga caaaaacggt aaaaaaggtt ttaccgcaac 122401 tgtcattcca aaccgtggcg catggttaga atacgaaact gatgcgaaag atgttgttta 122461 tgtccgcatt gatcgcacac gtaagttgcc ggttacggtt cttttgcgtg ctctcggctt 122521 cggctccgat caagagattc ttgatctcat aggagaaaac gaatacctgc gaaatacgct 122581 tgataaagat aacacagaaa acagcgacaa agcgttgctg gaaatttacg agcgtctccg 122641 tcctggagag ccgcctacag tagaaaatgc gaaaagcttg cttgattctc gtttctttga 122701 tccgaaacga tacgatcttg ccaatgtagg acgctataaa attaataaaa aacttcatat 122761 taagaatcgc ctcttcaatc agagacttgc tgaaacgctt gttgatcctg aaacaggaga 122821 aatccttgct gaaaaaggcc agattcttga tagaagaacg cttgataaag tactgccata 122881 cttagaaaac ggaatcggtt ttagaaagct gtatccgaat ggcggcgttg ttgaagatga 122941 agtgactctt caatcaatta aaatctttgc tccgactgat caagaaggag aacaggttat 123001 caatgtaatc ggcaatgctt acatcgaaga agagattaaa aacatcacgc ctgctgatat 123061 tatttcttca atcagctact tcttcaacct gctgcacgga gtaggcgaca cagatgatat 123121 cgatcatctt ggaaaccgcc gtttacgttc tgtaggcgag cttctccaga accaattccg 123181 tatcggttta agccgtatgg agcgtgtggt tcgtgagaga atgtcaattc aagatacgaa 123241 tacaattacg cctcagcagc tgatcaatat tcgtcctgtt attgcgtcca ttaaagagtt 123301 ctttggaagc tcacagcttt ctcaattcat ggatcagacg aacccgcttg ctgaattaac 123361 gcacaagcgt cgtctgtcag cattaggacc gggcggattg acacgtgagc gtgccggaat 123421 ggaagtgcgt gacgttcact actcccacta tggccgtatg tgtccgattg aaacgcctga 123481 gggcccgaac atcggtttga tcaactcact atcatcttat gcaaaagtaa accgttttgg 123541 ctttattgaa acgccatatc gccgcgttga ccctgaaaca gggaaggtaa cgggcagaat 123601 cgattactta actgctgatg aagaggataa ctatgttgtc gctcaagcga atgctcgtct 123661 tgatgacgaa ggcgccttta ttgatgacag catcgtagct cgtttccgcg gggagaacac 123721 cgttgtttcc agaaatcgtg tagactacat ggatgtatcg cctaagcagg ttgtatctgc 123781 tgcgacagca tgtatcccgt tcttagaaaa cgatgactcc aaccgtgccc tcatgggagc 123841 gaacatgcag cgtcaggctg tgcctttgat gcagccggaa gcgccatttg ttggaactgg 123901 tatggaatac gtatcaggaa aagactctgg tgccgctgtt atttgtaaac accctggtat 123961 cgttgaacgc gtagaagcca aaaacgtttg ggttcgccgt tatgaagaag tagacggtca 124021 aaaagtaaaa ggaaacctgg ataaatacag cctgctgaaa tttgtccgct ctaaccaagg 124081 tacgtgctac aaccagcgtc cgatcgtaag tgtcggcgat gaagtggtaa aaggagaaat 124141 ccttgctgac ggtccttcta tggagcttgg tgaacttgca cttggccgta acgtaatggt 124201 cggcttcatg acgtgggatg gctacaacta tgaggatgcc atcatcatga gtgaacgcct 124261 agtgaaggat gatgtttata catctatcca cattgaagaa tacgaatcag aagcacgtga 124321 tacgaaactt ggacctgaag aaatcactcg cgatattcca aacgtcggtg aagatgcgct 124381 tcgcaatctt gatgaccgcg gaatcatccg tattggggca gaagtaaaag acggagatct 124441 tcttgttggt aaagtaacgc ctaaaggcgt aactgaactg actgccgaag aacgccttct 124501 tcacgccatc tttggcgaga aagcccgcga ggttcgtgat acttctcttc gtgtgcctca 124561 tggcggcggc ggaattatcc atgacgttaa agtcttcaac cgtgaagacg gagacgaact 124621 tcctccaggt gttaaccagt tagtacgcgt atatatcgtt cagaaacgta agatttctga 124681 aggggataaa atggccggtc gtcacggtaa caaaggtgtt atctctaaga ttcttcctga 124741 agaggatatg ccttaccttc ctgacggcac accaattgat atcatgctta acccgctggg 124801 cgtaccatca cgtatgaaca tcgggcaggt attggaactt cacatgggta tggccgctcg 124861 ttaccttggc attcacattg catctcctgt atttgacgga gcgcgagaag aggatgtctg 124921 ggaaacactt gaagaagccg gcatgtctcg tgacgccaaa acagtgcttt acgacggacg 124981 tactggagag ccgtttgata accgtgtatc tgtcggtatc atgtacatga tcaaactggc 125041 tcacatggtt gacgataaac ttcatgcacg ctctacaggc ccttactcac ttgttacgca 125101 gcagcctctt ggcggtaaag cgcaatttgg cggacagcgt tttggtgaga tggaggtttg 125161 ggcacttgaa gcttacggtg cggcttacac tcttcaagaa attctgactg ttaagtctga 125221 tgacgtggtt ggacgtgtga aaacatacga agccatcgtt aaaggcgaca atgttcctga 125281 accaggtgtt ccggaatcat tcaaagtatt aatcaaagaa cttcaaagct taggtatgga 125341 tgtcaaaatc ctttctggtg atgaagaaga aatagaaatg agagatttag aagacgaaga 125401 agatgcgaaa caagctgacg gcctggcatt atcaggtgat gaagagccgg aagaaacagc 125461 atctgcagac gttgaacgcg atgtagtaac aaaagaataa tctctagtta taaaggcaag 125521 tgacatcggt taatccgaag ataaaaaggg aggtaggccc cttgctagat gtgaacaatt 125581 ttgagtatat gaacatcggt cttgcttcac cagataaaat ccgttcatgg tcttttggtg 125641 aagtgaaaaa gcctgaaacg ataaactatc gtacgttaaa acctgaaaag gacggtctat 125701 tctgcgaacg cattttcgga ccgactaagg actgggaatg tcattgcggg aagtacaagc 125761 gagttcgtta taaaggcgta gtttgtgacc gctgcggagt cgaagtaaca cgggctaaag 125821 tccgtcgtga gagaatgggg cacattgaac tggctgcccc agtttcccac atttggtatt 125881 tcaaaggtat tccaagccgt atgggtcttg tgctggatat gtcacctcgt gctttagaag 125941 aagtcattta ctttgcttct tacgttgtaa ctgatccggc gaatacaccg cttgaaaaga 126001 aacagcttct gtctgagaaa gaataccgtg cttatcttga taaatacggt aataaattcc 126061 aagcatctat gggtgctgaa gcaattcata aacttcttca agatatcgat cttgtaaaag 126121 aagttgatat gttaaaagaa gagctgaaaa cttcacaagg acaacgccgt actcgtgcga 126181 tcaaacgtct tgaagtttta gaagccttcc gtaactcagg aaacaagcct tcttggatga 126241 tccttgatgt gcttcctgtt attcctccgg agcttagacc gatggttcag ctagatggcg 126301 gacgttttgc gacttctgat ttgaatgacc tttatcgtcg tgtcatcaac cgtaacaatc 126361 gtttgaaacg ccttttggac cttggtgcgc ctagcatcat cgttcaaaac gaaaagcgta 126421 tgcttcaaga ggctgtcgat gccctaattg acaacggccg ccgcggacgc cctgtaacag 126481 gtcctggaaa cagaccgtta aaatctcttt ctcacatgct gaaagggaag caaggccgtt 126541 tccgtcaaaa ccttcttggt aaacgtgtcg attactccgg acgttctgta atcgttgttg 126601 gtcctcattt gaaaatgtac caatgcggat taccgaagga aatggcactt gaacttttca 126661 aacctttcgt tatgaaagaa cttgttgaaa aaggtcttgc tcacaacatt aagagtgcga 126721 aacgcaaaat tgagcgcgta cagcctgaag tttgggatgt actagaatca gttattaagg 126781 agcatccggt actgctgaac cgtgccccta cacttcacag attaggtatc caggcgtttg 126841 aaccaacgct tgttgaagga cgcgcaatcc gtcttcaccc gctcgtatgt acagcttaca 126901 acgctgactt tgacggtgac caaatggcgg ttcacgtacc attatctgct gaagcacaag 126961 ctgaagcacg catcttgatg cttgctgctc aaaacatctt gaaccctaaa gatggtaaac 127021 cggttgtaac accgtctcag gatatggtac taggtaacta ttacctgaca cttgagcgtg 127081 ccggtgctgt cggtgaaggt atggtcttca agaatacaga cgaagcgctt cttgcttatc 127141 aaaacggata tgttcacctt catacgagag tagctgttgc agctaactca cttaagaatg 127201 tgacatttac cgaagaacag cgctcaaaat tgttaattac aactgtcggt aagcttgtct 127261 tcaatgaaat tcttccggaa tcattccctt acatgaatga accaacgaag agcaacattg 127321 aagagaaaac acctgaccgt ttcttcttag aaaaaggtgc tgatgttaaa gctgttatcg 127381 cacagcagcc aatcaatgcg ccgtttaaaa aaggcattct gggtaaaatc atcgcggaaa 127441 tctttaaacg attccatatt acggaaacgt ctaaaatgct tgaccgcatg aaaaacctag 127501 gtttcaaata ttcaactaaa gctggtatta cagttggggt ttctgacatc gtcgtactcg 127561 atgataaaca agaaattctt gaggaagcgc aaagcaaagt tgacaacgtt atgaagcaat 127621 tccgccgcgg tcttatcact gaagaagaac gctatgagag agtcatctct atctggagtg 127681 ctgcaaaaga cgttatccaa ggcaaactga tgaaatcact tgatgaactc aacccgatct 127741 acatgatgag tgactctggt gcccgtggta acgcatctaa ctttacgcag cttgccggaa 127801 tgcgcggcct gatggccaac ccggctggac gtatcattga gttgccgatc aaatcaagtt 127861 tccgtgaagg tctgacagta ttggagtact ttatctccac acacggtgcg cgtaaaggtc 127921 ttgccgatac cgctcttaaa actgctgact caggttacct tacacgccgt ctcgttgacg 127981 ttgctcagga tgttatcatc cgtgaaactg attgcggaac tgaccgaggc attcttgcta 128041 agcctcttaa agaaggaact gaaacaattg agcgcttaga agaacgctta atcggacgtt 128101 ttgcaagaaa acaagtgaag caccctgaaa caggtgaagt gcttgtgaat gaaaacgaac 128161 tgatcgatga agataaagca ctggagattg tcgaagccgg cattgaagaa gtgtggatcc 128221 gttctgcctt cacatgtaat acgcctcatg gtgtatgtaa acgatgctat ggccgaaatc 128281 ttgcaactgg ctccgatgtt gaagtcggtg aagctgtcgg aatcattgct gcccaatcaa 128341 tcggtgagcc tggtacacag ttaacaatgc gtacattcca tacaggcggg gttgccggag 128401 acgatatcac acagggtctt ccgcgtatcc aagagctttt cgaagcgcgt aatccgaaag 128461 gtcaggcaac aattacagaa atcgacggta cagtcgttga gatcaatgaa gttcgtgata 128521 agcaacagga aattgtggtt caaggcgcag tggaaacacg ttcttatacg gcaccttaca 128581 actcccgcct gaaagtagcg gaaggagata aaattactcg aggccaagta ctgacagaag 128641 gttcaatcga tccgaaagaa cttcttaaag tgactgacct gacgactgtt caagagtatc 128701 ttctccatga ggttcaaaag gtttaccgta tgcagggtgt tgaaatcggt gataaacacg 128761 tagaagtaat ggttcgccag atgcttcgca aagtacgcgt gattgatgcc ggtgacactg 128821 atgtgcttcc aggtacattg cttgatattc accaatttac tgaagcgaac aaaaaggtat 128881 tgcttgaagg caaccgacca gctacaggcc gtcctgtctt actcggtatt acaaaagcat 128941 ctcttgaaac tgattcattc ttatctgctg cttccttcca ggaaacaaca cgtgtcctta 129001 cagatgcagc gatcaaaggt aagcgtgacg agcttctcgg cttgaaagag aatgttatca 129061 tcggtaagct tgttccagca ggtacaggaa tgatgaaata ccgtaaagta aaaccagtat 129121 caaatgttca gccgactgac gatatggtcc cggttgaata actgatttaa ctctgctgaa 129181 agactgcaaa aacagtcttt cagcagatat atttatgaaa aagtcactct atgagaagaa 129241 cgaatctaaa aaatgtcata ccttgttgac attcgtctcc tagaatgata atataaccaa 129301 ggtgctcgaa ataaacctgt tactttggag gatatgttta tgtcttatga taaagtatca 129361 caggccaaat caattattat tggtacgaag caaacagtga aagctctaaa gcgaggttca 129421 gtaaaggaag tagtcgttgc aaaagacgca gatccgatac tcacgtcaag tgttgtttca 129481 cttgctgaag atcaaggtat ctctgtctca atggttgaat ccatgaaaaa gctcggcaaa 129541 gcctgcggaa ttgaggtagg agcagccgct gttgccatta ttttataacg tacttttgtt 129601 tttgcgtaag attccatctt gtgtaaagac attgtttttt gccttttgat gaaccacctg 129661 ggtatgtggg ttataaaacg taatgaaggg aggaaaaatt catgcctaca attaatcagc 129721 taattcgcaa aggacgcgtg agtaaagtag aaaactcaaa gtctcctgca cttaacaaag 129781 gatacaacag ctttaaaaaa gagcacacta acgtatcttc tccacaaaaa cgcggggtat 129841 gtactcgtgt tggtacaatg acaccgaaaa aaccgaactc agcacttcgt aaatatgctc 129901 gtgttcgttt gactaacgga atcgaggtta ctgcttacat tcctggtatc ggtcacaacc 129961 tgcaagagca cagtgttgta cttatccgcg gcggacgtgt aaaagactta ccaggggtac 130021 gttaccacat cgttcgtggt gcgcttgata ctgctggagt tgaaaaccgt gcacaaggcc 130081 gttctaaata cggtacgaaa aaacctaaag caaaataata tacgaaaata cgcataattg 130141 atgaagggag gatattcaga tgccacgtaa aggtcctgta gcaaaaagag atgttttacc 130201 tgatccgatt tacaactcta agcttgtatc tcgtttaatc aacaaaatga tgatcgatgg 130261 taaaaaaggt aagtctcaaa cgatcctata caagtcattc gatatcatta aagaacgtac 130321 tggcaatgat gcaatggagg ttttcgaaca agcattgaaa aacatcatgc ctgtacttga 130381 agtaaaagca cgccgtgtag gtggtgcgaa ctaccaagtt cctgtagaag ttcgtcctga 130441 acgtcgtacg actcttggac ttcgctggtt agttaactac gctcgtcttc gtggagaaaa 130501 aacgatggaa gagcgtttag ctaacgaaat ccttgacgca gctaacaaca ctggtgctgc 130561 tgttaagaaa cgtgaagaca ctcataagat ggctgaagca aacaaagcat ttgctcacta 130621 tcgctggtag gatttataga ttaacaaaac acaatttcct aataaggaag gagaaattac 130681 ccaatggcaa gagagttctc cttagaaaaa actcgtaata tcggtatcat ggctcacatc 130741 gatgccggta aaacgactac tacagaacgt atcttgttct atactggtcg tatccacaaa 130801 attggtgaaa ctcatgaagg agcttcacaa atggactgga tggagcagga acaagaacgt 130861 ggtatcacaa tcacttccgc tgcgactact gcacagtgga aaggataccg cgtaaacatc 130921 atcgatactc caggacacgt agacttcaca gttgaagttg aacgttctct tcgtgtactt 130981 gatggtgctg ttgctgtact tgacgcgcaa tcaggcgttg agcctcaaac agaaactgtt 131041 tggcgtcagg caacaactta tggagtaccg cgtatcgttt ttgttaacaa aatggacaaa 131101 atcggtgcag acttccttta ctctgtagga actttaagag accgtcttca agcaaacgct 131161 catgcaattc aattgccgat cggtgctgaa gataacttcg aaggtatcat tgaccttgta 131221 gaaaacgttg cgtatttcta cgaagatgac ctcggaactc gttctgatgc aaaagaaatc 131281 cctgaagagt acaaagagca agctgaagag cttcgcaaca gccttattga agctgtatgt 131341 gagcttgatg aagagcttat ggataagtac cttgagggtg aagaaatcac aattgacgag 131401 ttaaaagcag gaattcgtaa aggtacatta aatgttgaat tctaccctgt tcttgttggt 131461 tctgccttca aaaacaaagg tgttcaacta gtacttgatg ctgttcttga ctaccttcct 131521 gcaccaactg acgttgctgc aatcaaaggt acacgtcctg atacaaatga agagattgag 131581 cgtcattctt ctgacgaaga gccattctct gcattagcat ttaaagttat gactgaccct 131641 tacgttggta agttgacgtt cttccgtgtg tactctggaa cacttgattc tggttcatac 131701 gtgaaaaact ctactaaagg caaacgtgag cgtgttggac gtattcttca aatgcacgct 131761 aacagccgtg aagaaatctc tactgtatac gcaggggata tcgcagctgc tgtaggtcta 131821 aaagatacaa ctactggaga tactctatgt gatgagaagg atcttgttat ccttgagtca 131881 atggaattcc cagaaccagt tatcgacgtt gctattgagc ctaaatcaaa agctgaccaa 131941 gataaaatgg gtatcgcttt agcgaaactt gctgaagaag atcctacatt ccgtactcaa 132001 acaaacccag aaactggcca aacgatcatc tctggtatgg gtgaacttca ccttgatatc 132061 attgttgacc gtatgaaacg cgaatttaaa gtagaagcca atgttggtgc tcctcaagtt 132121 gcgtaccgtg aaacattccg taccggtgca aaagttgaag gtaaattcgt acgtcagtct 132181 ggtggacgcg gtcagttcgg acacgtttgg atcgaattcg aaccaaacga agaaggcgct 132241 ggctttgaat ttgaaaatgc gattgtcggt ggggtcgttc ctcgtgaata catcccagct 132301 gttcaagcag gtctggaaga tgcactcgaa aatggtgtac tagcaggctt cccgcttatc 132361 gacattaaag ctaaactttt cgacggttct taccatgatg ttgactcaaa cgaaatggca 132421 tttaaagtcg ctgcttctat ggcattgaaa aatgcagtca gcaaatgtaa cccagttctt 132481 cttgaaccaa tcatgaaagt ggaagtggtt attccagaag aatatatggg agatatcatg 132541 ggtgatatca cttcacgtcg cggacgcgta gaaggtatgg aagcacgcgg taacgctcaa 132601 gttgttcgtg ctatggttcc tcttgctgaa atgttcggtt acgctactgc acttcgttct 132661 aatacgcaag gtcgcggtac gttcactatg cacatggatc actacgaaga agtgccgaag 132721 agcgtcgcag aagaaattat caaaaaaaat aaaggcgaat aattgatttt gccgcttaac 132781 tcaagtataa ctactattgt aagatgagga agtgaaagct ttctttcact tcctatcact 132841 ctatacatta ctaattaaaa gctcttaagg aggattttag aatggctaaa gaaaaattcg 132901 accgttccaa atcacatgcc aatattggta caattggaca cgttgaccat ggtaaaacaa 132961 ctttaactgc tgctatcaca acagtacttc ataagaaatc tggtaaaggt acagctatgg 133021 cgtacgatca aattgatggt gctccagaag aacgcgagcg cggtatcaca atctctactg 133081 cacacgttga gtacgaaact gaaactcgtc actatgcaca cgttgactgc ccaggacacg 133141 ctgactatgt taaaaacatg atcactggtg ctgcgcaaat ggacggagct atccttgtag 133201 tatctgctgc tgatggccca atgccacaaa ctcgtgagca catccttctt tctaaaaacg 133261 ttggtgtacc atacatcgtt gtattcttaa acaaatgcga catggtagac gacgaagagc 133321 ttcttgaact agttgaaatg gaagttcgcg atcttcttag cgaatacgac ttccctggtg 133381 atgatgtacc agttgttaaa ggttctgctc ttaaagctct tgaaggagac gctgagtggg 133441 aagctaaaat cttcgaactt atggatgcgg ttgatgagta catcccaact ccagaacgcg 133501 acactgaaaa accattcatg atgccagttg aggacgtatt ctcaatcact ggtcgtggta 133561 cagttgctac tggccgtgta gaacgcggac aagttaaagt cggtgacgaa gttgaaatca 133621 tcggtcttca agaagagaac aagaaaacaa ctgttacagg tgttgaaatg ttccgtaagc 133681 ttcttgatta cgctgaagct ggtgacaaca ttggtgccct tcttcgcggt gtatctcgtg 133741 aagaaatcca acgtggtcaa gtacttgcta aaccaggtac aatcactcca cacagcaaat 133801 tcaaagctga agtttacgtt ctttctaaag aagagggtgg acgtcatact ccattcttct 133861 ctaactaccg tcctcagttc tacttccgta caactgacgt aactggtatc atccatcttc 133921 cagaaggcgt agaaatggtt atgcctggag ataacactga aatgaacgtt gaacttattt 133981 ctacaatcgc tatcgaagaa ggaactcgtt tctctattcg tgaaggcgga cgtactgttg 134041 gttcaggcgt tgtttctaca atcactgagt aatagtatgg ttttaaacga gacccctgtg 134101 ggtctcgttt tttgtttgct tatctttttc ttgtataata ggatctatca tattcgaggg 134161 gttaatattt atgattcctg aaaagaaatc aatcgcaatc atgaaagaac taagcattgg 134221 aaatacaaag caaatgctga tgattaatgg agttgacgtg aaaaatccat tgctgctttt 134281 tttacatggc gggccgggaa cgccgcaaat cggatatgtt agacattatc aaaaagagct 134341 ggaacagtat tttacagtag ttcattggga tcagagagga tcggggcttt cttattctaa 134401 gcgaatttcg catcactcta tgacaataaa tcacttcatt aaagatacaa tccaagtcac 134461 tcaatggctt ttagctcatt tttcaaaatc aaaactttac ctagccggtc attcttgggg 134521 atcaatactg gcgcttcatg tgctgcagca gcgtcctgat ttattttaca cgtattatgg 134581 aatcagccag gttgttaacc cgcaagatga agaatcaact gcttatcaac atattcgtga 134641 aatttccgaa tcaaaaaaag ccagcatatt atctttcctt acacgtttca ttggtgctcc 134701 gccttggaag caggatatcc agcaccttat ctatcggttt tgtgttgagc taaccagggg 134761 aggattcact caccgtcatc gtcaatctct cgctgtatta tttcaaatgc ttactggcaa 134821 tgagtatgga gtgcggaaca tgcacagctt ccttaatgga ttgcgcttca gtaaaaaaca 134881 tttaactgat gagttgtacc ggtttaatgc ttttacatca gttccttcta ttaaagtacc 134941 gtgtgttttc atttcaggga aacatgactt aattgttcct gcagaaatat cgaaacagta 135001 ttatcaagaa cttgaggcac ctgaaaagcg ctggtttcaa tttgagaatt cagctcacac 135061 cccgcatatt gaggagccat cattattcgc gaacacatta agtcggcatg cacgacacca 135121 tttatgatag atccttgata aataagaaaa acccctgtat aataaaaaaa gtgtgcaaat 135181 catgcatatt ttaaataagt cttgcaacat gcgcctattt tctgtataat ggtgtatgtt 135241 ggtctttgac tgcgatgaag tgagaggttg ctgacacacc cggccgcttt gccatggcaa 135301 ggtgttcagg tttttctcac ggagaactgt ctaacgtgat gtaggcgaaa aggagggaaa 135361 ataatggcaa aacaaaaaat tcgtattcgt ttgaaagcat atgatcatag aatccttgat 135421 caatctgcag agaagattgt tgaaacggca aaacgttctg gtgccagcgt atctggtccg 135481 attccgttgc caactgaaaa atcagtttac acaatccttc gtgcggtgca caaatacaaa 135541 gattctcgtg agcaatttga aatgcgtaca cataaacgtt taatcgacat tgtgaaccca 135601 acaccacaaa ctgttgatgc tcttatgcga ttagacttac catctggtgt cgatatcgaa 135661 attaaacttt aattctaaaa tatagaatga tcttaatagg aggtgtgacg aatgaccaaa 135721 ggaatcttag gaagaaaaat tggtatgacg caagtattcg ctgagaatgg tgatcttatt 135781 ccggtaactg ttatcgaggc tgctccaaac gttgttcttc aaaagaaaac agctgaaaac 135841 gacggttacg aagcaatcca gcttggtttt gacgacaagc gtgaaaagct ttctaacaaa 135901 cctgaaaaag ggcacgttgc aaaagcggaa actgctccta agcgcttcgt taaagaatta 135961 cgcggagtgg aaatggatgc gtatgaagtt ggtcaggaag tcaaggttga aattttctct 136021 gctggagaaa tcgtagatgt aacaggagta tctaaaggta aaggtttcca aggtgcgatc 136081 aagcgccacg gacaatctcg cggacctatg tctcacggtt cacgctacca ccgtcgtcct 136141 ggttcaatgg gacctgtaga tcctaaccgt gtattcaaag gtaaattatt acctggacgt 136201 atgggcggag agcaaatcac tgttcaaaac cttgaaatcg taaaagttga tgcagaacgc 136261 aatcttcttt tgatcaaagg taacgtacct ggtgcgaaga aatctttaat cactgttaaa 136321 agtgctgtta aatctaaata attctcttag gaaaggagga aattgattat gccaaaagta 136381 gcattataca accaaaacgg ttctactgct ggtgacatcg aattaaacgc ttctgtattt 136441 ggtatcgaac caaatgagag tgttgtattc gacgctattc ttatgcaaag agcttcctta 136501 cgtcaaggaa ctcacaaagt aaaaaatcgt tctgaagtac gcggcggagg tcgtaaacca 136561 tggcgtcaaa aaggtactgg acgtgcccgt caaggttcaa tccgttcacc gcaatggcgc 136621 ggaggtggtg tcgtattcgg cccaacacca cgcagctatt cttataaatt acctaaaaaa 136681 gttcgccgct tggcaatcaa atcagtattg tcttctaaag tgatcgacaa caacatcatc 136741 gttcttgaag atcttactct tgatacggct aaaacaaaag aaatggcagc tatccttaaa 136801 ggattatctg ttgagaaaaa agctttaatc gtaactgcgg atgcaaacga agcagtagca 136861 ttatctgctc gtaacattcc tggagttact gttgttgaag ctaacggaat caacgtttta 136921 gacgttgtca accacgagaa gcttctgatt acaaaagcag cggttgaaaa agtagaggag 136981 gtgcttgcat aatgaaagat cctcgtgatg ttctaaagcg ccccgtcatt actgaacgtt 137041 ctgccgattt aatgactgaa aaaaaatata cttttgaagt tgatgtaaga gctaacaaaa 137101 cagaagtgaa agacgcggtt gaaagcatct ttggagtgaa agttgacaaa gtcaacatca 137161 tgaactacaa aggcaaatca aaacgtgttg gacgctacac tggtatgact agccgtcgca 137221 gaaaagcgat cgtaaaactt actgcagaca gcaaagaaat cgaaattttt gaagcttaat 137281 tatctgtaaa aagaaggagg gaaattcaaa atggcgatta aaaagtataa accgacctct 137341 aatggacgtc gtggcatgac aacttcagat tttgctgaaa tcacgactga caagccggaa 137401 aaatccttgc ttgctcccct tcacaaaaaa ggcggacgta acaaccaagg taaattgact 137461 gtacgtcacc aaggtggcgg acataaacgc caataccgtg ttatcgactt caaacgcgat 137521 aaagatggta tacctggacg cgttgctaca gttgaatacg atccaaaccg ttcagctaac 137581 atcgctctaa tcaactatgc agacggagaa aaacgttaca ttcttgctcc taaaggaatt 137641 caagtaggta ctgaaatcat gtcaggtcct gaagctgaca ttaaagtagg taatgcactt 137701 ccacttatca acatccctgt tggtacagtt gtgcataaca ttgaattaaa acctggtaaa 137761 ggcggacagc ttgtacgttc agctggtaca tctgctcagg ttcttggtaa agaaggtaaa 137821 tacgttcttg tacgtcttaa ctctggtgaa gttcgcatga tcctttctgc ttgccgtgct 137881 tctatcggtc aagtaggtaa cgaacagcac gaacttatca acattggtaa agctggacgt 137941 tctcgctgga aaggcatccg tcctacagtt cgtggttctg taatgaaccc taacgatcac 138001 ccacacggtg gtggtgaagg acgtgcgcca atcggacgta aatcaccaat gtctccatgg 138061 ggcaaaccaa ctcttggatt caagactcgt aagaaaaaga acaaatccga taaatttatc 138121 gtacgtcgtc gtaaaaataa ataacggggt tgtctacggt tcttttcgga ccgtagtgca 138181 atcacgaagg gaggttccaa aatggctcgc agcttaaaaa aaggaccatt tgtcgatgga 138241 cacttgatga ctaaaatcga gaaattaaat gaaacagaca agaaacaagt cgtaaaaact 138301 tggtctcgtc gttctactat tttcccacag tttattggtc acacaatcgc agtctatgac 138361 ggacgtaaac acgtgcctgt attcatctct gaagatatgg tagggcacaa gttgggtgaa 138421 ttcgctccaa ctcgtacgta caaaggtcat gctagtgatg acaaaaaaac aagacgctaa 138481 gagaggaggc ttttaaatgc aagctaaagc tgttgcaaga acagtccgta ttgctcctcg 138541 taaagcacgt ctagtaatgg acctgattcg aggcaagcaa gtaggtgagg cagtatcaat 138601 cttgaacctt acaccaagag ctgcttctcc aattatcgag aaagtattaa aatccgctat 138661 tgcaaatgct gagcataact atgaaatgga cgctaacaac ctggttattt ctcaagcatt 138721 cgttgacgaa ggccctacgt taaaaagatt ccgcccacgt gctatgggac gtgcgagcca 138781 aatcaacaaa cgtacgagcc acattacaat cgttgtatca gaaaagaagg agggataagt 138841 agtgggtcaa aaggtaaatc cagtcggtct tcgtatcgga gtcattcgtg attgggaatc 138901 taagtggtac gctggtaaag attacgctga cttcctgcac gaagatttaa aaattcgtga 138961 atacattagc aaacgccttt ctgacgcttc tgtttctaaa gtagaaattg agcgtgcagc 139021 aaaccgcgtt aacattacga tccacacagc taagcctggt atggttatcg gtaaaggcgg 139081 ttctgaagtc gaagcacttc gcaaagccct taacagcctt actggcaagc gtgtacacat 139141 taacattctt gaaatcaaaa gagcagatct tgatgcacag ctagttgctg acaacatcgc 139201 tcgtcaatta gaaaaccgtg tttctttccg ccgtgcgcag aaacaacaaa tccaacgtac 139261 tatgcgtgct ggagcacaag gtgtgaaaac aatggtttct ggtcgtcttg gcggtgcaga 139321 tatcgctcgt tctgaatact acagtgaagg aactgttcca ttgcacacat tacgtgcgga 139381 cattgactat gcaacatctg aagctgatac tacttacggt aagcttggtg taaaagtctg 139441 gatctatcgt ggagaggttc ttcctactaa gaagaaaaat gaggaaggag gaaaataata 139501 tgttattacc aaaacgcgtt aaatatcgca gagagcatcg cggaaaaatg cgtggccgtg 139561 cgaaaggcgg tactgaagta catttcggag aattcggtat ccaagctcta gaagcttctt 139621 ggattactaa ccgtcaaatc gaagctgcac gtattgcgat gactcgttac atgaaacgtg 139681 gcggtaaagt ttggatcaaa attttccctt ctaaacctta cactgctaaa ccacttgagg 139741 tacgtatggg atccggtaaa ggggctccag aaggttgggt agctgttgta aaaccgggca 139801 aagttttatt tgaaatttct ggtgtgtctg aagaggttgc tcgtgaagcg cttcgccttg 139861 catctcacaa attgccaatt aaaacgaagt tcgtaaaacg tgaagaaatt ggtggtgaat 139921 caaatgaaag ctaatgaaat tcgtgacctt accactgctg aaattgaaca aaaagtaaag 139981 tctcttaaag aagaactttt caatcttcgc tttcaattag cgacaggaca acttgaaaat 140041 actgctcgca ttcgtgaagt gcgcaaagct atcgcgcgca tgaaaactgt gattcgtgaa 140101 agagaaattg ctgctaataa ataatcactg aggggaggtc gtgagcatga gcgaacgtaa 140161 ccaacgcaaa gtttaccaag gccgtgttgt ttctgacaaa atggataaaa ccattactgt 140221 tgttgttgag acatacaaaa aacatacact ttacggtaaa cgcgtaaaat actcaaaaaa 140281 attcaaagca catgatgaaa ataatcaagc taaaatcggt gacatcgtta agatcatgga 140341 aactcgtcca ttgtctgcaa ctaagcgttt ccgtctagtt gaagttgtcg aagaagctgt 140401 tattatctaa taaagttcgg aattcttttt ccgaagggag gtaacaaata atgattcaac 140461 aagagactcg tttaaaagta gctgacaact ctggcgcacg tgaagtactt actattaaag 140521 ttcttggtgg ttctggacgt aaaacagcta acattggtga tgtaattgtt tgcacggtta 140581 aacaagcaac accaggaggc gttgtcaaaa aaggtgaagt cgtaaaagct gttatcgttc 140641 gcactaaaag cggagcgcgc agaagtgacg gttcatacat cagcttcgat gagaatgcat 140701 gtgttatcat ccgtgacgac aagagcccac gcggaactcg tatcttcgga ccagttgctc 140761 gtgaattgcg tgaaaacaac tttatgaaaa ttgtttctct agctccagaa gttatctaat 140821 tgaaataaat gccttactca aggaggtgcg atcaggatgc atgtaaaaaa aggcgataaa 140881 gttatggtta tctctggtaa agataaaggc aaacaaggaa caatccttgc tgctttccct 140941 aaaaaggacc gcgttttagt tgaaggtgtt aacatggtaa agaaacactc taaaccaact 141001 caagctaacc ctcaaggcgg tatttctaat caagaggcgc caattcatgt atcaaacgtt 141061 atgccgctcg atcctaaaac aggtgaagtg actcgcgtag gatacaaagt ggaagatggc 141121 aaaaaagttc gtgtagcaaa aaaatctggg caagttctag ataaatagta ttaaaaggaa 141181 gggaggtcta tctcatgaac cgccttaaag aaaagtacaa taaagaaatt gcacctgctt 141241 taatgactaa gttcaactat gattcagtca tgcaagtgcc taaaatcgaa aaaatcgtaa 141301 tcaacatggg tgttggtgac gctgttcaaa acgccaaagc aatcgacagt gctgttgagg 141361 aattaacgtt tatcgcaggt caaaaacctg tcgttactcg tgcgaagaaa tcaattgctg 141421 gattccgtct tcgtgaggga atgcctatcg gtgcgaaagt aactcttcgc ggagagcgca 141481 tgtatgattt ccttgataaa cttatttctg tatctttacc gcgtgtacgt gacttccgcg 141541 gggtttctaa aaaatctttc gacggtcgcg gtaactacac acttggtatc aaagaacagt 141601 taatcttccc tgaaattgac tacgataaag taacaaaggt tcgcggaatg gacatcgtta 141661 tcgtaacaac tgctaatact gacgaagaag ctcgtgagct attaactcaa gtaggtatgc 141721 cgttccagaa ataatcaatg aaagggaggc gaaatcgtgg ctaaaaagtc tatgattgcg 141781 aaacaacaac gtacaccaaa gtttaaagta caagagtaca cacgctgtga acgctgcgga 141841 cgtccgcatt cagtcattcg taaatttaaa ctttgccgta tttgtttccg tgagcttgca 141901 tataaaggac aaattcctgg cgtgaaaaaa gccagctggt aatccccaag aaagggaagg 141961 aggtaattat ataatggtta tgacagatcc aattgcagat atgctaactc gtattcgcaa 142021 tgcaaacatg gtacgtcatg agaagcttga aattcctgct tctaaattga aaagagaaat 142081 tgctgaaatt ttaaagcgtg aaggtttcat tcgtgacgtt gagttcgtag aagacagcaa 142141 acaaggtatt atccgcgttt tcttgaaata cggacaaaac aacgagcgcg ttatcactgg 142201 tcttaaaaga atcagcaagc ctggtttgcg tgtttatgct aaatctaatg aagtaccccg 142261 cgtacttaac ggtcttggaa tcgcgattat ttctacatca caaggtgttt taacggacaa 142321 agaagcccgt gcaaaacaag ctggtggaga agttctagca tacgtttggt aagaagttta 142381 acatgaatgg aggtgtttgg tatgtctcgt gtaggtaaga agctacttga gattccttct 142441 gatgttacag taacgttaaa tgataacaac actgtagctg tgaaaggacc aaaaggagaa 142501 ttaactcgta cgtttcaccc tgatatggag attaaagtag aggacaatgt gcttacagtc 142561 gctcgtcctt ctgatcaaaa agagcaccgt gccctgcatg gtacgactcg cagtctgctt 142621 ggcaacatgg ttgaaggtgt atctaaagga tttgaaagag gtttggaatt agtcggtgtc 142681 ggttaccgtg cttctaaatc cggaaataaa cttgttttaa acgttggata ctctcatcct 142741 gttgagatcg ttcctgaaga aggcatcgaa atcgaagttc cttctcaaac aaaagtagtt 142801 gtaaaaggta cagacaaaga acgcgtagga gctattgctg ctaacatccg cgctgtacgt 142861 tctccagagc cttacaaagg taaaggaatc cgctacgaag gtgaagttgt tcgccgtaaa 142921 gaaggtaaat ctgctaagta agatcgctta aagtgaagaa aggagtgacc tagatgatta 142981 cgaaaactag caaaaatgct gctcgtctta aaagacacgc tcgtgttcgc gctaaacttt 143041 ccggtactgc tgaaagaccg cgcctgaacg ttttccgttc taacaagcac atttacgctc 143101 aaatcatcga tgatgtaaat ggtgtaacac ttgctagtgc atctactctc gataaagact 143161 tgaacgttga aagcactgga gatacttctg ctgctactaa agttggagaa ttagttgcaa 143221 aacgcgctgc tgaaaaaggc atttctgacg tagtatttga ccgtggcgga tacttatacc 143281 atggacgtgt aaaagctttg gctgatgccg ctcgtgaagc tggacttaaa ttttaataaa 143341 agaaggaggg acacatgatt atgcgtcgta ttgacccaag caaattagag ttagaagaac 143401 gcttagttac ggttaaccgc gtagcgaaag ttgttaaagg tggtcgtcgt ttccgcttcg 143461 cagctctagt cgttgtcggt gacaaaaacg gacacgtagg attcggtact ggtaaagcac 143521 aagaagtacc agaagcgatt cgcaaagctg ttgaagatgc gaaaaagaat ttgattgaag 143581 taccaatggt tggaactaca attccacacg aaatcatcgg acgtttcggt gcaggtaaca 143641 tcttgttaaa acctgcttct gaaggtactg gagttatcgc tggaggccct gtacgtgcgg 143701 tacttgagct agctggtgta gctgatatcc tttctaagtc tttaggttct aacacaccga 143761 tcaacatgat tcgtgcaaca cttcaaggtt taagtgaact taaacgtgct gaagacgttg 143821 cgaagcttcg tggaaaatct gtagaagaac tgttaggata aggagggaac attaatggct 143881 aaattagaaa ttaccctcaa acgaagtgta atcggtcgcc cggaagacca acgcgttact 143941 gtaagaacac ttggtttaaa gaaaacaaac caaactgttg ttcatgaaga caacgctgcg 144001 atccgtggta tgattaataa agtatctcat ttagtttctg ttaaagaaca ataaaaatat 144061 ttgatcggat aaggaggtgt cctaatgaaa cttcatgaat taaaaccttc agaaggttca 144121 cgcaaaacgc gtaatcgcgt aggtcgtggt attggttctg gcaacggtaa aacagctggt 144181 aaaggtcaca aaggtcaaaa cgctcgttct ggcggcggtg tacgccctgg attcgagggg 144241 ggacaaatgc ctttattcca acgtcttcct aaacgtggtt tcactaacat caaccgcaag 144301 gaatacgctg tagtcaacct agacaaattg aacggttttg cagaaggaac ggaagtcact 144361 cctgaacttc ttctagagac tggtgttatt agcaaactta atgcaggagt aaagattctt 144421 ggcaacggta aattagagaa aaaattaact gtaaaagcca ataaattctc tgcttctgcg 144481 aaagaagctg ttgaagctgc tggcggtaca gctgaggtga tctaacttgt ttaaaacaat 144541 ctccaacttt atgcgtgtga gtgatatcag gaataaaatc atattcactt tactcatgct 144601 tatcgtcttt cgcataggtg cgtttattcc tgtgccttac gttaacgctg aagcgttaca 144661 ggcacagtct caaatgggtg tttttgatct ccttaataca tttggcggcg gtgcgcttta 144721 ccaattttcc attttcgcaa tgggaattac tccttatatc acggcttcga tcatcattca 144781 gctgcttcag atggatgtgg taccgaagtt taccgagtgg tctaagcaag gtgaagttgg 144841 ccgccgtaaa ttagctcagt tcacaaggta ctttacgatt gtgcttggtt tcatccaagc 144901 gttaggtatg tcatatggat tcaacaatct ggcaaacggt atgctgatcg aaaaatccgg 144961 tgtatcgaca tatcttatca ttgctttagt gctcactggc ggaactgcct ttttaatgtg 145021 gcttggggaa caaattactt ctcatggagt aggcaacgga atatcgatca ttatcttcgc 145081 ggggattgtg tctagtattc caaaaacaat tgggcaaata tatgagactc aatttgtcgg 145141 cagcaacgat cagttgttta ttcatattgt gaaagtcgca cttcttgtga ttgcgatttt 145201 agcagttatt gttggagtta ttttcattca gcaagccgta cggaaaattg cgattcaata 145261 tgctaaaggc acaggtcgtt cacctgctgg cggaggtcag tctacacacc ttccattgaa 145321 agtgaatcct gcaggggtta ttccggtaat ctttgcggtt gcgtttttga taacgccgcg 145381 gacgatcgcg tcattctttg gaacaaacga tgtgacaaag tggattcaaa acaactttga 145441 taatacgcat ccggtgggta tggcgatata tgttgcgttg attattgcct ttacgtactt 145501 ttatgctttt gtacaggtaa accctgaaca aatggctgat aaccttaaaa aacagggtgg 145561 ctatatcccg ggggttcgtc cagggaaaat gactcaagat agaattacga gcattttgta 145621 tcgacttacg tttgtgggtt ctatattctt agccgtgatt tccattcttc ctatcttttt 145681 cattcaattc gctggattgc ctcaaagtgc acaaattggc ggaacatctt tgttaattgt 145741 tgtcggggta gccttggaga caatgaaaca actagaaagc cagttggtga aacgaaacta 145801 ccgtggattt atgaaaaact agaggaaatg gatttatcca ttccctctta ataaagagag 145861 gacgggggaa atccgaatga acttagtctt aatggggctt cctggtgccg gtaaaggcac 145921 acagggcgaa cgaattgttg aggattatgg gattcctcat atctcaacag gagatatgtt 145981 ccgtgctgct atgaaagaag aaacaccact cggactcgaa gcaaaatctt atattgataa 146041 gggagagctc gtacctgacg aagtcacaat cggaattgta aaagagagac ttggcaaaga 146101 tgattgtgaa agaggttttc ttctggacgg atttccgcga acagtcgctc aagccgaagc 146161 tcttgaagaa attcttgagg aatacggcaa gccgattgat tatgtcatta acattgaagt 146221 cgacaaagat gttctgatgg aacgtctgac tggacgcaga atttgcagtg tttgcggcac 146281 aacctatcat ttagtcttta atccgccgaa aacgccgggt atttgtgata aagacggagg 146341 cgaactctat caacgggcag atgataatga ggaaacagtc tctaaacggc ttgaggtaaa 146401 catgaagcaa actcagcctt tactcgattt ctattcagag aaaggttatc ttgcaaacgt 146461 gaatggccag caggacattc aagacgttta tgcagatgtg aaggatcttc ttggaggatt 146521 aaaaaaatga ttatctgtaa aaccccacgt gaacttggta tcatgcggga agcagggcga 146581 atcgtggctt taactcatga agagttaaaa aagcacatta aaccaggaat ctcgacaaaa 146641 gaattggatc aaattgccga acgttttatt aagaagcagg gtgcaatccc atcttttaag 146701 gggtataatg ggtttcgcgg gagcatttgc gtatcagtta atgaagaact cgttcacggc 146761 atacctggca gcagggtgct gaaggacggt gacatcatca gtattgatat cggtgctaaa 146821 ttaaatggtt atcatggtga ctctgcatgg acatatccgg taggaaacat cagcgatgat 146881 gacaaaaaac ttctggaagt gacagaggag tctttatata aaggcttgca ggaagcaaaa 146941 ccaggtgaac gtttgtcgaa tatttcccac gcaatacaaa cgtatgtcga aaatgagcag 147001 ttttcagttg ttagggagta tgtcggacat ggtgttggtc aagacttgca tgaggacccg 147061 caaattcctc attacggtcc gcccaacaaa ggaccacggc ttaaacctgg catggttctc 147121 gctattgaac ctatggtgaa cgctggcagc cgctacgtga aaacattggc tgataactgg 147181 acggttgtaa cggtagatgg gaaaaagtgt gctcattttg aacatacgat tgcgattacg 147241 gaaacgggtt ttgatatact gacgagagtc tagatgatga aaataattcc gaagacagat 147301 gtttttcaag cttgataggg cagaaagctt gggtgaacat tggcaagacc gaattcatct 147361 tgcttcttgt cgttggaatt ttaaccatca tcaatgtact aacagcagac ggagaaaagc 147421 gtacatttca ttctcctaag aaaaagaata tcaatcattt aaccctttat gattgcgtat 147481 ctccggaagt tcagaacagt ataaacgaaa cagggcgtgt gacaaacttc ttttgaaatt 147541 tgtcagaaag caagttactg atttgaagaa gggagaacac ttgaatggcg aaagacgatg 147601 taattgaagt ggaaggtact atagtcgaaa cactgccaaa cgcgatgttc aaagttgaac 147661 ttgaaaatgg ccacactgtt ttggctcatg tatctggtaa aatccgcatg cacttcattc 147721 gcattttacc tggagacaaa gttacggtag aattatctcc atatgactta actcgtggca 147781 ggattacgta ccgttacaaa taaagcactc cggaaactga aggaggttgg aaacacatga 147841 aagtgagacc atcagttaaa ccaatctgcg aaaaatgtaa agttattcgc agaaaaggaa 147901 aagtaatggt gatctgtgaa aatccaaagc ataaacaaaa acaaggataa tttataagga 147961 ggtgcccaga gaatggctcg tattgctggt gtagatatcc cacgtgacaa acgtgttgtt 148021 atttctttaa catacatctt cggaattggc cgcacaacgg ctcagcaagt tttaaaagaa 148081 gctggagttt cagaagatac tcgtgtgcgc gatcttactg aagaagaact tggtaaaatc 148141 cgtgatatta ttgacaaact gaaagtagaa ggtgaccttc gccgtgaagt ttctcttaat 148201 atcaaacgtc tgatcgaaat cggaagctac cgcggaatcc gtcatcgcag aggattacct 148261 gttcgcggac aaaactctaa aaacaacgcg cgtactcgta aaggtccgcg tcgtactgta 148321 gctaacaaga aaaaataagt aagggaggtt cttaaacaat ggctgctgct cgtaaatcta 148381 acacgcgtaa acgtcgcgtg aaaaagaata ttgagtctgg aattgctcat attcgttcaa 148441 ctttcaataa cacgatcgtt acgatcactg acactcatgg taatgctatt tcttggtcta 148501 gtgccggagc tttaggattc agaggttctc gtaaatctac tccttttgct gcgcaaatgg 148561 ctgcagaaac agctgctaaa ggttcaatcg aacatggtct taaaactcta gaggttactg 148621 ttaaaggacc tggttcaggc cgtgaagctg caatccgtgc acttcaagct gctggactag 148681 aagtcactgc tatcagagac gtaactcctg ttcctcataa cggatgccgt ccaccaaaac 148741 gtcgccgcgt gtaatttgtt tgtatagatt ttgtgtccct gtcaataatg ggttatgata 148801 cagttattta tgaaacgaat gcaccgactc gttgcctgag cacatacggg actaaacaat 148861 ggggaatttc ggatggaatc tcatatgatt ctattcgagg tttcgacgtt ttgaaggagg 148921 gttttaagta atgatcgaga ttgaaaaacc aaaaatcgaa acggttgaaa tcagcgacga 148981 tgccaaattt ggtaagtttg tcgtagagcc acttgagcgt ggatatggta caactctggg 149041 taactcctta cgtcgtatcc tcttatcctc actccctggt gccgctgtaa catcaatcca 149101 gatagatggt gtactgcacg aattctcgac aattgaaggc gttgtggaag atgttacaac 149161 gattatctta cacattaaaa agcttgcatt gaaaatctac tctgatgaag agaagacgct 149221 agaaattgat gtacagggtg aaggaactgt aacggcagct gatattacac acgatagtga 149281 tgtagagatc ttaaatcctg atcttcatat cgcgactctt ggtgagaatg cgagtttccg 149341 agttcgcctt actgctcaaa gaggacgtgg gtatacgcct gctgacgcaa acaagagaga 149401 cgatcagcca atcggcgtga ttccgatcga ttctatctat acgccagttt ctcgtgtatc 149461 ttatcaggta gagaacactc gtgtaggcca agttgcaaac tatgataaac ttacacttga 149521 tgtttggact gatggaagca ctggaccgaa agaagcaatt gcgcttggtt caaagatttt 149581 aactgaacac cttaatatat tcgttggttt aactgacgaa gctcaacatg ctgaaatcat 149641 ggttgaaaaa gaagaagatc aaaaagagaa agttcttgaa atgacaattg aagaattgga 149701 tctttctgtt cgttcttaca actgcttaaa gcgtgcgggt attaacacgg ttcaagagct 149761 tgcgaacaag acggaagaag atatgatgaa agttcgaaat ctaggacgca aatcacttga 149821 agaagtgaaa gcgaaactag aagaacttgg actcggactt cgcaaagacg attgactagt 149881 ttcccttgtg aactaggatt ttcgtgtgtt tattattcag aaacagcatt ccaataaagg 149941 aggggacatc acatgtcata cagaaaacta ggacgtacga gtgcacagcg taaagctatg 150001 cttcgtgatc ttacaactga tttgatcatc aacgaaagaa tcgaaacaac tgaaacacgt 150061 gcgaaagaac ttcgctctgt agttgaaaaa atgatcacgc ttggcaaacg cggtgatctt 150121 cacgctcgcc gtcaagctgc tgcatacatc cgcaacgagg ttgcaaacga agaaaataat 150181 caagatgcac ttcaaaaatt attctctgac attgcaactc gttacgagga gcgccaaggt 150241 ggatacacac gtattatgaa gcttggtcct cgccgtggtg acggagcacc aatggcaatt 150301 atcgaattgg tttaatcaca tatttttgtg tatctaaaga agggcgggac agtttctaac 150361 tggatctatg cccttttttt agatactgca acttttaata gagagaaaag cagagcatta 150421 gctgagagga ggccggtttt ccatgaatca aaatcagttg atatcggtag aggatatcgt 150481 atttcgatat cggaaggacg cagaaagacg agcactagac ggcgtctccc tgcaggtgta 150541 tgagggtgaa tggcttgcaa tcgtaggtca taacggttca gggaaatcaa cactggcccg 150601 ggcattgaat ggtttaattc ttcctgaatc aggcgacatt gaggttgccg ggattcaatt 150661 gacagaggaa tctgtttggg aagtgcgtaa gaagataggt atggtctttc aaaatccgga 150721 taaccaattt gtcggaacga ctgttcgcga tgatgtggct tttggtttag aaaacaatgg 150781 tgtaccgcgg gaagaaatga ttgagagagt agactgggca gtaaaacagg tgaatatgca 150841 agattttctc gatcaagagc cgcaccatct ctccggaggc caaaagcaga gagttgcgat 150901 tgcgggggtt attgccgcac gtcctgatat tattatctta gatgaagcaa catccatgct 150961 tgatccgatc gggcgagaag aagtgcttga aacggtaaga catttaaaag agcagggcat 151021 ggcgactgtc atatccatta cacatgacct gaatgaggca gcaaaagcag acaggatcat 151081 tgtcatgaat ggcggtaaaa aatatgctga agggccgcct gaagagattt ttaaattgaa 151141 taaagaactt gttcgaattg ggcttgattt acccttctca ttccagctta gccagctttt 151201 aagagaaaat ggactggctt tggaagaaaa ccatttgact caggaagggc tggtgaaaga 151261 gctgtggaca ttacaatcaa agatgtagag catcgctatc agatgaagac cccgtttgag 151321 cgcctagcac tgtatgatat caatgcatcg attaaagaag gaagctacgt agccgttatc 151381 gggcatacag gctctggcaa gtccactctt ctacagcacc taaatggtct cctgaagccg 151441 acgaagggac agatatcact aggcagcact gtcattcagg cagggaaaaa gaataaagat 151501 ctgaaaaaac ttcgtaaaaa agtcggaatc gttttccaat ttcctgagca tcaattattc 151561 gaagaaacag ttcttaaaga tatttcattc ggaccgatga actttggtgt taaaaaagaa 151621 gatgctgaac aaaaagcgag agagatgctg cagcttgtag gtttatcaga agagcttttg 151681 gacaggtcac cctttgaatt aagcggggga caaatgcgca gagttgcaat tgccggcgta 151741 cttgcaatgg accctgaagt gcttgttctg gatgaaccga ctgcaggatt ggacccaaga 151801 gggcgaaaag agattatgga catgttttat gagcttcatc aacgtgggaa cttgacgacg 151861 atccttgtga cacacagcat ggaggatgca gctgcatacg ctgatgaaat gattgttatg 151921 cataaaggaa cgatacaagc atcaggcagt ccgcgtgatc tgtttttaaa gggtgaagag 151981 atggccggct gggggctgga tcttcctgaa acaataaaat tccaaagaca ccttgaagct 152041 gcactgggtg tgagatttaa tgagcctatg ctcacaatcg aagatgccgc tgccgaaatc 152101 cgtgctcttt ttcagggaga gaagacttta tgatggacag catgattatc ggcaagtatg 152161 taccggggac ttcacttgtg caccggcttg accccagaac aaaactgatc acgatctttt 152221 tatttgtctg cattgtattc ttagccaata atgttcagac atatgcgttg cttggtttat 152281 ttacaattgg cgtcgtttct ttaacaagag ttcctttctc ttttttaatg aaagggctga 152341 agccaatcat ctggattgtc ctttttacgt tccttcttca cattcttatg acacatgaag 152401 gaccgattat ctttcaaata ggttttttca aagtctatga gggcggtctg gttcagggga 152461 tattcatttc tcttagattc gtctatttga ttttaatcac aaccttatta acgcttacga 152521 ctacaccgat tgagattacc gatggaatgg agcagctgct gaacccattg aaaaaattaa 152581 agcttcctgt tcatgagctg gctcttatga tgtcaatttc tttacggttt attccgacac 152641 tgatggagga gacagataag atcatgaagg ctcagatggc gcgaggcgtt gattttacaa 152701 gcgggcctgt caaagaaaga gtgaaggcta ttgtcccgct tcttgtcccg ctcttcgtca 152761 gcgcatttaa acgcgccgaa gagcttgcgg tggcaatgga agcaagaggc tatcaaggcg 152821 gagaaggacg tacgaaatat agaaagcttg tatggacagg aaaagacact tctgtcattg 152881 tcagcttaat tgtattagct gctttgttat ttttcttaag ggcttagagg tgctgtatga 152941 gactgaaatg cacgatttct tatgacggac atttgtttaa cggttatcag gttcagccgg 153001 gcaaaagaac ggttcaggat gaactggaga aggctttggc tgtcctgcat aagtcaaaag 153061 acagaattcc ggtcgtttcg tctggaagaa cagacagcgg ggttcacgca gccggacagg 153121 tgattcattt tgacactccg ctgtctatcc cggctgagag atggccatat gccttaaatg 153181 cactgcttcc ggacgatatc gcagtcaaac aggcagaaat tgcggatgat gggttccatg 153241 cacgatttag cgcagtcaaa aaagaatatc gctactttgt atacacggag aaacacccgg 153301 acgtatttaa acggcattac gcttaccatt tttcatatcg ccttaatgtg caggacatga 153361 gagaagcggc aaagcatctt atagggacac atgattttac gagcttttgc gcggctaaaa 153421 cagaagtgca ggacaaggta agaacgatat acgaacttga ttggactgag acggctgacg 153481 gcctgcaaat gcggatcaca ggcagcggtt tcttatataa tatggtcaga attattgcgg 153541 gtactttgct tgatgcaggt attggaaaaa tttctcccga tgaggtgaaa tccatgctgg 153601 aagcgaagga tcgcgaagcg gcagggcgca cagcgccggg gcacgggcta tatttatgga 153661 acgtttacta tgacaactaa accaggtgta taatattttc ttgacagagt ctgcataaag 153721 ttataagata tcatatggta tgtatttcaa ccccacgata agccccggaa cttattgtgt 153781 tgtgaaatag aacgtaatcg aagtttattg aaaatgacag atcatttagg agggaaattc 153841 aatgcgtaca acacctatgg ctaacgcaag tactattgaa cgcaagtggt tagttgttga 153901 tgctgctggc aagactttag gtcgtctttc ttcagaagtt gcagctatcc ttcgcggaaa 153961 acacaaacca acttacacac cacacgttga tactggagat catgtgatca tcatcaacgc 154021 tgaaaaaatc gagttaactg gtaaaaagtt aactgacaaa atctactacc gtcacactca 154081 acatccaggc ggattaaaat caagaactgc tcttgaaatg cgtacaaact accctgagaa 154141 aatgcttgag cttgctatca aaggcatgct tccaaaaggt tctctaggtc gtcaaatgtt 154201 caaaaaattg aacgtatacc gtggttctga gcatccacac gaagcacaaa aacctgaagt 154261 ttacgaactt cgcggttaat taaaaaggag gttaccaatt tggcacaggt tcaatattac 154321 ggtactggcc gtcgtaaaag ctctgtagcg cgtgtgcgtt tagttccagg agaaggccgt 154381 atcgtcgtta ataatcgtga aatcagcgaa catatcccat ctgcagcttt aatcgaagat 154441 atcaaacaac cattaacttt gactgaaaca gctggcactt atgatgtttt agtaaacgta 154501 catggaggcg gcctatctgg tcaagctgga gcaatccgtc acggtatcgc tcgtgctttg 154561 cttgaagcag atccagaata ccgtacaact cttaaacgtg caggtcttct gactcgtgac 154621 gctcgtatga aagaacgtaa aaaatacggt cttaaaggcg ctcgtcgtgc acctcagttc 154681 tcaaaacgtt aattttacgt tttcaaaaag ctctcgacct tgggttggga gcttttttct 154741 ttcaataaaa cgtggcagtc ccgcataaaa ataacaactg aatggacgct tgacggggtt 154801 aagcaaattg tttgtttata aacggtctct ttgtaataat catggtagat ttcattctta 154861 ttcaattgga agttcggtca atgtttatta tcgttatgtg atcagcccag ctccatctaa 154921 ccactgtatc tcatccgtta aagttcactg ctgattctta acccggagaa acaatagctc 154981 tcattgctaa tggctttatg taacgaagta aaagtaaatc tgatgatata aatcacatat 155041 ctcctttgtg atttttttgc gtttttatga acttttttct aaatatgcaa agggaaagcg 155101 atatcaatct agaaatattt gttatactct atacattaaa gtaaggagaa gattcatgaa 155161 tgcgttagta gctcataata gcaaagcctg ggataaaaaa gtagaaacag gcaatgaatg 155221 gactgttgct gttgaacagc aggttatcga acaagcaaaa aaaggcaatt gggatataag 155281 ggtaacacca atgaaagatg taccgaagga ttggtttccg cctatcaaag gtctgaaagt 155341 actctgttta gcatcaggcg gcggccagca gggtccagtt ttggcagccg caggcgcgga 155401 tgtcactgta ttagataact cagaaaaaca gctgaatcag gatagaatga ttgctgagcg 155461 agatggtctg acgatacaca ctgtcaaagg aagcatggac gatttaagtg tatttaatga 155521 tgaatcattt gatgtcattg tacatcctgt tgccaatgtt tttgttgaga atgtcctccc 155581 ggtatggaag gaagcgtacc gtgtgttgaa aaggaacggc attctaatct cgggttttgt 155641 caatcctgtt gtatttctgt ttgatacaga attagaacag caaggtgttt taaaagtaaa 155701 acactctatt ccatacgctg acccagaaga tcttccgaaa cataaagtga aaaaactgat 155761 cgaaaataat gaggctctgg aattcggcca ttccttagaa gaccaaatca aaggccaaat 155821 tgatgccggt tttatcgtta ctggttttta tgaagataaa ggcggttttg tattagacca 155881 atatatccat acatattctg caacaagaag cgtgaaagta tgaaaagcag cgacctgtta 155941 gaggggctgc ttttttcata accaattaca gaacatttgt tcctcaccct gcagaaagct 156001 gattttttat caatgttaca ccttcatttg ggcgaatttc caaccgaatt cgggcattgt 156061 ttcatcatcc aaacctcaaa ataatcggta aaaggagagt gaatttatat ggcagaagta 156121 ctgtctttta tggatgtgaa acgccaaaag gattttgaat tagaaaagaa cttgctcaaa 156181 gaactctctc tgagacaaat tatccagtct gttaaggatt gtttggaacc attatttcca 156241 tttttacatg atgaacgaga tattattacc gaaggctgta ttgattttgc gattgaagct 156301 tatttgttag gcgggcgttt tgggatattc ggctattacg gagaatcaat gcagagtatc 156361 agtgcccgct ctgcaagaga agaagaagag ctgcgtatgg agttttttga ttatctctat 156421 aattggatac acgagcaata cgcaacattt gataaaaaca ctgtttatga agcggcacgc 156481 aagttcatta aagattggtg gacagcaggg tttgttcaaa gagaaaaaca gtgtaagctt 156541 cgcatgcggt aatcatattt cccgaccctg tcccatagtt atgtaataac ggacaagcgg 156601 gaggggaagg gatgaggaaa aagcttaaat ggctcagttt tttgctaggc ttcatcatat 156661 tactatttct gttcaagtat cagttcagca ataacgactc ttggaagccg tggagcctgc 156721 ccttgagcgg taaaatcatt tatctagatc caggtcatgg cgggcctgac ggcggagcag 156781 tcggcggaaa gctgttagag aaggatgtta ccctggaagt ggcctttaga gtcagggatt 156841 atcttcaaga acaaggagcg cttgttatca tgaccagaga aagtgatact gatctcgctc 156901 cagaaggaac aaaaggctat agccgacgaa aagctgagga tctaagacaa cgagtcaaat 156961 taataaacca ttcagaggcg gagctctata tcagcattca tcttaatgcg attccgtcac 157021 aaaaatggag cggagcccaa agcttttatt acgggaaata tgcggaaaat gagaaagtcg 157081 caaaatacat tcaggatgag ctgagaagaa atctggaaaa cacaacccgg aaagcaaagc 157141 ggattcatgg tatctactta atgcaaaacg tcaccaaacc gggggcgctt atagaagtcg 157201 gatttttatc caatccaagt gaagcaacgt tgctcggtaa accgaaatat caagacaagg 157261 tggcatcttc catatataaa ggcattttgc gatatttcac agaaaaagga gaccctccgg 157321 agtaatggag ggttttcttg tggttctaag cataagacac ccgccattta tgtatgatat 157381 aataataatt gtaaacgaat acacaaaagg gtgaggttcg atgataagag aagatgaagt 157441 aagaaaacta gtcggagaaa tgcgcgaacc ttttcttcaa agacctctgg gagaattgga 157501 tgccgttaag gaaattaaaa taaagcctga aaaacggcat atcagtgtaa aagtcgctct 157561 tgcaaaaaca ggaactgcag aacaaatgca gattcagcaa gagatcgtaa acgtattaaa 157621 aggggcagga gctgagacag tcggccttcg atttgaagag ctgcctgaag aaacggttgc 157681 taaattccgg gcgccgtcag ctgagaaaaa aacattatta aatatggata acccgccagt 157741 ctttcttgct gtagcaagtg gaaaaggcgg cgtaggcaag tcaactgtgt cagtaaacct 157801 agctatttct ctggctcgtc tagggaaaaa ggttggttta attgatgcgg atatttatgg 157861 gttcagtgtg ccggacatga tgggtatcac tgtgcgtcca acaattgaag gagagaaact 157921 tcttcctgtt gaacgctttg gagtaaaggt catgtcaatg ggctttttcg tagaagaaaa 157981 tgccccggtc gtatggagag ggccgatgct cggcaaaatg ctgaataatt ttttccatga 158041 agtagagtgg ggagaagtag actatatcgt tcttgatctt ccgcctggta caggggacgt 158101 tgctctcgat gtacatacaa tgcttccgag ctgcaaagaa attatcgtat ctacgccaca 158161 tccgacagct gcttttgtcg cggccagagc gggctctatg gcgattaaaa ccgatcatga 158221 ggtcgtgggt gtcatagaga acatggctta ttatgaaagt gcaaagacag gggaaagaga 158281 atatgtgttt ggaaaaggcg gaggagataa actggctgag gaactaaacg tgcctttgct 158341 cggcagaatc ccattgaaac agcccgattg ggataaggac caatttgctc cgtctgttta 158401 tgacgaaaat catccaatcg gagaaatata tcaggacatc gcaaaaaaaa tagatgcaaa 158461 aatgtcagtg caggtataaa aggtgaaccg ggattccaga tcccggcttt ccctttattc 158521 actttctttt gctgtgtctt ttgctgcttt tttcagctca tcttcgaact gctttttgta 158581 aagcggacta gaaagtgttt cgttaataac ctcttctaaa taactgcgga attcttggct 158641 ttttgccagc tggctgtact ttttatccat gccgggatcc tgcataacgc tcatcagcat 158701 cttctggtaa tctggatcct tcatcagctt tttaatcact ttttcatgct ctgtctgaag 158761 agttttggca aagccctcag caaaatcagt gtcttcaaag atgtttttcc aaaattcttc 158821 acctttttta gatgtgagtg ttttttctat tgttccttta attgcatctt ggtcaatcac 158881 cagcgcttca ttcatggcat catcatttaa taattcctta atagctttct ttccatcatc 158941 agtttttaat atatcaacaa ccattttttt ggtctgatca tagtccatat ccgctgcttg 159001 gtcttttgga gcgcaagctg ttacagataa taacaaaaaa cagctcatca atagcgtttt 159061 ggcttttgac atgcttaagc tcctttcaca tacttgtctt acctttaata tgattcatct 159121 gtttggaatt atacataaca aaatatcgct gttcgcgatt tttgagggga tgaataaaga 159181 aatgaaaagc cgtggtttag ttcgtttttt cttttctatt ttagctgtcg gggcgcttat 159241 cacgagtatt gtgggttttg ctttaaagtg gggagaatat agagggctgt ttctaacatt 159301 tgaagcggga cagattttct ctgttttatt ttggtttatc ggtgtaggca tgattttcag 159361 tgtgatcagc caaatgggtt ttttcgtgtt tttaacagtt catcggtttg cgcttgagat 159421 attaaggtcc tcctctttgt ggaatttgct gcagttgttt ttcatcctgt ttgttgcttt 159481 tgatttaatg tacgtgcgtt ttttattttt tggagagagc ggagaatcgc tggctggcta 159541 tgcgtggtta ccggtgtttt tattgatctt tggagtgatt acagcttata taaagcaaaa 159601 gcagtcctct aagaaaacat ttgtgtcatc gttatttttg atggttgtga ttaccgcatt 159661 agaatggttc cctgcattaa gagtaaatga tgaggactgg ctttatttaa tgctttttcc 159721 gttaatggca tgtaatgcct tccaattgct gatgctgccg aagtttgcag caaagtaatt 159781 actttacctc tgcggatttg gcatcagaat ttgcgatgag atcacccacg gttacatttt 159841 ttaatccttt ttctttcagc tgatggatga tatcaggcaa tgcttcttct gtttgttttg 159901 cagaatcgga ggcatgtaaa agaataatgt ctccaccgga aacttgcttg gtcacattgt 159961 cgatgatttt ttcaactccg ggatttgtcc agtcttgaga gttcacactg taatgaacga 160021 ctgtataatt gtattgcttt gcgaccttta gaacattctt attgaattgg ccggtagggg 160081 gtcttaatag ctgtatgtct ttgaccccta acttttcaaa ggctgtttgc gcacggttca 160141 tgtccttttt tatttcgctg ctctctaaat tggcatagtt tttataagcg tagcccatgc 160201 tcccgatttg atggccgtcc tttacgatac gggccactgt gtcgggatgg cgttctgccc 160261 aagaagcgga caggaaaaac gttgcgtttt taatcccgtt tgctttcaga gtattaagta 160321 tcggttctgc tctctcatca ccccagctga tatcgaaagt aagtgaaata tctttagagt 160381 ctgtttctcc tttataaatg gctttaggtc cggtgtcagt tgaaaacacg ggaagcggga 160441 cagctctttg gatataaaaa aagctggcag ctgcaaatgc ggcgataagt ataataatta 160501 attgttttac ccgtttaatg tgccacacat agaagtgatt cactgatgat gcctccttat 160561 cttgtccatc attcttgttt tacatcttat gagcatggac aattgaatat aaccgataaa 160621 atgtctcttc acatacagcc taaattgggt gttgaccttt tgataatatc cgtgatatat 160681 tattattcgt cgctgataaa cagctgacat caactaaaag cttcattaaa tactttgaaa 160741 aaagttgttg acttaaaaga agctaaatgt tatagtaata aagctgcttc gttaagcggc 160801 agtaatgatc tttgaaaact aaacaagaca aaacgtacct gttaattcat ttttataaat 160861 cgcacagcga tgtgcgtagt cagtcaaact actttatcgg agagtttgat cctggctcag 160921 gacgaacgct ggcggcgtgc ctaatacatg caagtcgagc ggacagatgg gagcttgctc 160981 cctgatgtta gcggcggacg ggtgagtaac acgtgggtaa cctgcctgta agactgggat 161041 aactccggga aaccggggct aataccggat ggttgtttga accgcatggt tcaaacataa 161101 aaggtggctt cggctaccac ttacagatgg acccgcggcg cattagctag ttggtgaggt 161161 aatggctcac caaggcaacg atgcgtagcc gacctgagag ggtgatcggc cacactggga 161221 ctgagacacg gcccagactc tacgggaggc agcagtaggg aatcttccgc aatggacgaa 161281 agtctgacgg agcaacgccg cgtgagtgat gaaggttttc ggatcgtaaa gctctgttgt 161341 tagggaagaa caagtaccgt tcgaataggg cggtaccttg acggtaccta accagaaagc 161401 cacggctaac tacgtgccag cagccgcggt aatacgtagg tggcaagctt tgtccggaat 161461 tattgggcgt aaagggctcg caggcggttt cttaagtctg atgtgaaagc ccccggctca 161521 accggggagg gtcattggaa actggggaac ttgagtgcag aagaggagag tggaattcca 161581 cgtgtagcgg tgaaatgcgt agagatgtgg aggaacacca gtggcgaagg cgactctctg 161641 gtctgtaact gacgctgagg agcgaaaacg tggggagcga acaggattag ataccctggt 161701 agtccacgcc gtaaacgatg agtgctaagt gttagggggt ttccgcccct tagtgctgca 161761 gctaacgcat taagcactcc gcctggggag tacggtcgca agactgaaac tcaaaggaat 161821 tgacgggggc ccgcacaagc ggtggagcat gtggtttaat tcgaagcaac gcgaagaacc 161881 ttaccaggtc ttgacatcct ctgacaatcc tagagatagg acgtcccctt cgggggcaga 161941 gtgacaggtg gtgcatggtt gtcgtcagct cgtgtcgtga gatgttgggt taagtcccgc 162001 aacgagcgca acccttgatc ttagttgcca gcattcagtt gggcactcta aggtgactgc 162061 cggtgacaaa ccggaggaag gtggggatga cgtcaaatca tcatgcccct tatgacctgg 162121 gctacacacg tgctacaatg gacagaacaa agggcagcga aaccgcgagg ttaagccaat 162181 cccacaaatc tgttctcagt tcggatcgca gtctgcaact cgactgcgtg aagctggaat 162241 cgctagtaat cgcggatcag catgccgcgg tgaatacgtt cccgggcctt gtacacaccg 162301 cccgtcacac cacgagagtt tgtaacaccc gaagtcggtg aggtaacctt ttaggagcca 162361 gccgccgaag gtgggacaga tgattggggt gaagtcgtaa caaggtagcc gtatcggaag 162421 gtgcggctgg atcacctcct ttctaaggat attatacgga atataagacc ttgggtctta 162481 taaacagaac gttccctgtc ttgtttagtt ttgaaggatc attccttcga aacgtgttct 162541 ttgaaaacta gataacagta gacatcacat tcaagtaata caagatatca catagtgatt 162601 ctttttaacg gttaagttag aaagggcgca cggtggatgc cttggcacta ggagccgatg 162661 aaggacggga cgaacaccga tatgcttcgg ggagctgtaa gcaagctttg atccggagat 162721 ttccgaatgg ggaaacccac cactcgtaat ggagtggtat ccatatctga attcatagga 162781 tatgagaagg cagacccggg gaactgaaac atctaagtac ccggaggaag agaaagcaaa 162841 tgcgattccc tgagtagcgg cgagcgaaac gggattagcc caaaccaaga ggcttgcctc 162901 tggggttgta ggacactctg tacggagtta caaaggaacg aggtagatga agaggtctgg 162961 aaaggcccgc cataggaggt aacagccctg tagtcaaaac ttcgttctct cctgagtgga 163021 tcctgagtac ggcggaacac gtgaaattcc gtcggaatcc gggaggacca tctcccaagg 163081 ctaaatactc cctagtgacc gatagtgaac cagtaccgtg agggaaaggt gaaaagcacc 163141 ccggaagggg agtgaaagag atcctgaaac cgtgtgccta caagtagtca gagcccgtta 163201 acgggtgatg gcgtgccttt tgtagaatga accggcgagt tacgatctcg tgcaaggtta 163261 agcagaagat gcggagccgc agcgaaagcg agtctgaata gggcgcatga gtacgtggtc 163321 gtagacccga aaccaggtga tctacccatg tccagggtga agttcaggta acactgaatg 163381 gaggcccgaa cccacgcacg ttgaaaagtg cggggatgag gtgtgggtag gggtgaaatg 163441 ccaatcgagc ctggagatag ctggttctct ccgaaatagc tttagggcta gcctcaaggt 163501 aagagtcttg gaggtagagc actgattgga ctaggggccc ctaccgggtt accgaattca 163561 gtcaaactcc gaatgccaat gacttatcct tgggagtcag actgcgagtg ataagatccg 163621 tagtcgaaag ggaaacagcc cagaccgcca gctaaggtcc caaagtatac gttaagtgga 163681 aaaggatgtg gagttgctta gacaaccagg atgttggctt agaagcagcc accatttaaa 163741 gagtgcgtaa tagctcactg gtcgagtgac tctgcgccga aaatgtaccg gggctaaacg 163801 tatcaccgaa gctgcggact gttcttcgaa cagtggtagg agagcgttct aagggctgtg 163861 aagccagacc ggaaggactg gtggagcgct tagaagtgag aatgccggta tgagtagcga 163921 aagaggggtg agaatcccct ccaccgaatg cctaaggttt cctgaggaag gctcgtccgc 163981 tcagggttag tcgggaccta agccgaggcc gaaaggcgta ggcgatggac aacaggttga 164041 tattcctgta ccacctcctc accatttgag caatgggggg acgcaggagg atagggtaag 164101 cgcggtattg gatatccgcg tccaagcagt taggctggga aataggcaaa tccgtttccc 164161 ataaggctga gctgtgatgg cgagcgaaat atagtagcga agttcctgat tccacactgc 164221 caagaaaagc ctctagcgag gtgagaggtg cccgtaccgc aaaccgacac aggtaggcga 164281 ggagagaatc ctaaggtgat cgagagaact ctcgttaagg aactcggcaa aatgaccccg 164341 taacttcggg agaaggggtg ctctgttagg gtgcaagccc gagagagccg cagtgaatag 164401 gcccaggcga ctgtttagca aaaacacagg tctctgcgaa gccgtaaggc gaagtatagg 164461 ggctgacgcc tgcccggtgc tggaaggtta agaggagcgc ttagcgtaag cgaaggtgcg 164521 aattgaagcc ccagtaaacg gcggccgtaa ctataacggt cctaaggtag cgaaattcct 164581 tgtcgggtaa gttccgaccc gcacgaaagg cgcaacgatc tgggcactgt ctcaacgaga 164641 gactcggtga aattatagta cctgtgaaga tgcaggttac ccgcgacagg acggaaagac 164701 cccgtggagc tttactgcag cctgatattg aatgttggta cagcttgtac aggataggta 164761 ggagccttgg aaaccggagc gccagcttcg gtggaggcat cggtgggata ctaccctggc 164821 tgtattgacc ttctaacccg ccgcccttat cgggcgggga gacagtttca ggtgggcagt 164881 ttgactgggg cggtcgcctc ctaaaggtaa cggaggcgcc caaaggttcc ctcagaatgg 164941 ttggaaatca ttcgcagagt gtaaaggcac aagggagctt gactgcgaga cctacaagtc 165001 gagcagggac gaaagtcggg cttagtgatc cggtggttcc gcatggaagg gccatcgctc 165061 aacggataaa agctaccccg gggataacag gcttatctcc cccaagagtc cacatcgacg 165121 gggaggtttg gcacctcgat gtcggctcat cgcatcctgg ggctgtagtc ggtcccaagg 165181 gttgggctgt tcgcccatta aagcggtacg cgagctgggt tcagaacgtc gtgagacagt 165241 tcggtcccta tccgtcgcgg gcgcaggaaa tttgagagga gctgtcctta gtacgagagg 165301 accgggatgg acgcaccgct ggtgtaccag ttgttctgcc aagggcatcg ctgggtagct 165361 atgtgcggac gggataagtg ctgaaagcat ctaagcatga agcccccctc aagatgagat 165421 ttcccattcc gcaaggaagt aagatccctg aaagatgatc aggttgatag gtctgaggtg 165481 gaagtgtggc gacacatgga gctgacagat actaatcgat cgaggactta accatatttt 165541 tgaatgatgt cacatctgtt atctagtttt gagagaacac tctcaatttg tttggtggcg 165601 atagcgaaga ggtcacaccc gttcccatac cgaacacgga agttaagctc ttcagcgccg 165661 atggtagtcg ggggtttccc cctgtgagag taggacgccg ccaagcagat ttattaattc 165721 taccatgttt gtttatgaag ctttatatct cattccgcag tagctcagtg gtagagctat 165781 cggctgttaa ccgatcggtc gtaggttcga atcctacctg cggagcattg cttccatagc 165841 tcagcaggta gagcacttcc atggtaagga agaggtcagc ggttcgagcc cgcttggaag 165901 cttaaatgta ttattaccaa ggtttctcat aaggagaaag ctttttttat tgcgatatgc 165961 ggaagtagtt cagtggtaga acaccacctt gccaaggtgg gggtcgcggg ttcgaatccc 166021 gtcttccgct ccatttacct aacgggatat tgtaaattga attgcgcccg tagctcaatt 166081 ggatagagcg tttgactacg gatcaaaagg ttaggggttc gactcctctc gggcgcgcca 166141 tatcttttaa tagaatagat aggaaatcgg gaagtagctc agcttggtag agcacatggt 166201 ttgggaccat ggggtcgcag gttcgaatcc tgtcttcccg accatttttt atggggcctt 166261 agctcagctg ggagagcgcc tgctttgcac gcaggaggtc agcggttcga tcccgctagg 166321 ctccaccaaa agtttttaaa aaaggttatt gactttgaag aagtgacatt gtatactaat 166381 aaagttgctt taacaaagcg gacaaacaaa atgatctttg aaaactaaac aagacaaaac 166441 gtacctgtta attcagtttt taaaaatcgc acagcgatgt gcgtagtcag tcaaactact 166501 ttatcggaga gtttgatcct ggctcaggac gaacgctggc ggcgtgccta atacatgcaa 166561 gtcgagcgga cagatgggag cttgctccct gatgttagcg gcggacgggt gagtaacacg 166621 tgggtaacct gcctgtaaga ctgggataac tccgggaaac cggggctaat accggatggt 166681 tgtttgaacc gcatggttca aacctaaaag gtggcttcgg ctaccactta cagatggacc 166741 cgcggcgcat tagctagttg gtgaggtaac ggctcaccaa ggcaacgatg cgtagccgac 166801 ctgagagggt gatccggcca cactgggact gagacacggc ccagactcta cgggaggcag 166861 cagtagggaa tcttccgcaa tggacgaaag tctgacggag caacgccgcg tgagtgatga 166921 aggttttcgg atcgtaaagc tctgttgtta gggaagaaca agtaccgttc gaatagggcg 166981 gtaccttgac ggtacctaac cagaaagcca cggctaacta cgtgccagca gccgcggtaa 167041 tacgtaggtg gcaagcgttg tccggaatta ttgggcgtaa agggctcgca ggcggtttct 167101 taagtctgat gtgaaagccc ccggctcaac cggggagggt cattggaaac tggggaactt 167161 gagtgcagaa gaggagagtg gaattccacg tgtagcggtg aaatgcgtag agatgtggag 167221 gaacaccagt ggcgaaggcg actctctggt ctgtaactga cgctgaggag cgaaagcgtg 167281 gggagcgaac aggattagat accctggtag tccacgccgt aaacgatgag tgctaagtgt 167341 tagggggttt ccgcccctta gtgctgcagc taacgcatta agcactccgc ctggggagta 167401 cggtcgcaag actgaaactc aaaggaattg acgggggccc gcacaagcgg tggagcatgt 167461 ggtttaattc gaagcaacgc gaagaacctt accaggtctt gacatcctct gacaatccta 167521 gagataggac gtccccttcg ggggcagagt gacaggtggt gcatggttgt cgtcagctcg 167581 tgtcgtgaga tgttgggtta agtcccgcaa cgagcgcaac ccttgatctt agttgccagc 167641 attcagttgg gcactctaag gtgactgccg gtgacaaacc ggaggaaggt ggggatgacg 167701 tcaaatcatc atgcccctta tgacctgggc tacacacgtg ctacaatgga cagaacaaag 167761 ggcagcgaaa ccgcgaggtt aagccaatcc cacaaatctg ttctcagttc ggatcgcagt 167821 ctgcaactcg actgcgtgaa gctggaatcg ctagtaatcg cggatcagca tgccgcggtg 167881 aatacgttcc cgggccttgt acacaccgcc cgtcacacca cgagagtttg taacacccga 167941 agtcggtgag gtaacctttt aggagccagc cgccgaaggt gggacagatg attggggtga 168001 agtcgtaaca aggtagccgt atcggaaggt gcggctggat cacctccttt ctaaggatat 168061 tatacggaat ataagacctt gggtcttata aacagaacgt tccctgtctt gtttagtttt 168121 gaaggatcat tccttcgaaa cgtgttcttt gaaaactaga taacagtaga catcacattc 168181 aagtaataca agatatcaca tagtgattct ttttaacggt taagttagaa agggcgcacg 168241 gtggatgcct tggcactagg agccgatgaa ggacgggacg aacaccgata tgcttcgggg 168301 agctgtaagc aagctttgat ccggagattt ccgaatgggg aaacccacca ctcgtaatgg 168361 agtggtatcc atatctgaat tcataggata tgagaaggca gacccgggga actgaaacat 168421 ctaagtaccc ggaggaagag aaagcaaatg cgattccctg agtagcggcg agcgaaacgg 168481 gattagccca aaccaagagg cttgcctctt ggggttgtag gacactctgt acggagttac 168541 aaaggaacga ggtagatgaa gaggtctgga aaggcccgcc ataggaggta acagccctgt 168601 agtcaaaact tcgttctctc ctgagtggat cctgagtacg gcggaacacg tgaaattccg 168661 tcggaatccg ggaggaccat ctcccaaggc taaatactcc ctagtgaccg atagtgaacc 168721 agtaccgtga gggaaaggtg aaaagcaccc cggaagggga gtgaaagaga tcctgaaacc 168781 gtgtgcctac aagtagtcag agcccgttaa cgggtgatgg cgtgcctttt gtagaatgaa 168841 ccggcgagtt acgatctcgt gcaaggttaa gcagaagatg cggagccgca gcgaaagcga 168901 gtctgaatag ggcgcatgag tacgtggtcg tagacccgaa accaggtgat ctacccatgt 168961 ccagggtgaa gttcaggtaa cactgaatgg aggcccgaac ccacgcacgt tgaaaagtgc 169021 ggggatgagg tgtgggtagg ggtgaaatgc caatcgaacc tggagatagc tggttctctc 169081 cgaaatagct ttagggctag cctcaaggta agagtcttgg aggtagagca ctgattggac 169141 taggggcccc taccgggtta ccgaattcag tcaaactccg aatgccaatg acttatcctt 169201 gggagtcaga ctgcgagtga taagatccgt agtcgaaagg gaaacagccc agaccgccag 169261 ctaaggtccc aaagtatacg ttaagtggaa aaggatgtgg agttgcttag acaaccagga 169321 tgttggctta gaagcagcca ccatttaaag agtgcgtaat agctcactgg tcgagtgact 169381 ctggcccgaa aatgtaccgg ggctaaacgt atcaccgaag ctgcggactg ttcttcgaac 169441 agtggtagga gagcgttcta agggctgtga agccagaccg gaaggactgg tggagcgctt 169501 agaagtgaga atgccggtat gagtagcgaa agaggggtga gaatcccctc caccgaatgc 169561 ctaaggtttc ctgaggaagg ctcgtccgct cagggttagt cgggacctaa gccgaggccg 169621 aaaggcgtag gcgatggaca acaggttgat attcctgtac cacctcctca ccatttgagc 169681 aatgggggga cgcaggagga tagggtaagc gcggtattgg atatccgcgt ccaagcagtt 169741 aggctgggaa ataggcaaat ccgtttccca taaggctgag ctgtgatggc gagcgaaata 169801 tagtagcgaa gttcctgatt ccacactgcc aagaaaagct ctagcgaggt gagaggtgcc 169861 cgtaccgcaa accgacacag gtaggcgagg agagaatcct aaggtgatcg agagaactct 169921 cgttaaggaa ctcggcaaaa tgaccccgta acttcgggag aaggggtgcc ctgttagggt 169981 gcaacccgag agaaccgcag tgaataggcc ccaggcgact gtttagcaaa acacaggtct 170041 ctgcgaagcc gtaaggcgaa gtatagggct gacgcctgcc cggtgctgga aggttaagag 170101 gagcgcttag cgtaagcgaa ggtgcgaatt gaagccccag taaacggcgg ccgtaactat 170161 aacggtccta aggtagcgaa attccttgtc gggtaagttc cgacccgcac gaaaggcgca 170221 acgatctggg cactgtctca acgagagact cggtgaaatt atagtacctg tgaagatgca 170281 ggttacccgc gacaggacgg aaagaccccg tggagcttta ctgcagcctg atattgaatg 170341 ttggtacagc ttgtacagga taggtaggag ccttggaaac cggagcgcca cttcggtgga 170401 ggcatcggtg ggatactacc ctggctgtat tgaccttcta acccgccgcc cttatcgggc 170461 ggggagacag tgtcaggtgg gcagtttgac tggggcggtc gcctcctaaa aggtaacgga 170521 ggcgcccaaa ggttccctca gaatggttgg aaatcattcg cagagtgtaa aggcacaagg 170581 gagcttgact gcgagaccta caagtcgagc agggacgaaa gtcgggctta gtgatccggt 170641 ggttccgcat ggaagggcca tcgctcaacg gataaaagct accccgggga taacaggctt 170701 atctccccca agagtccaca tcgacgggga ggtttggcac ctcgatgtcg gctcatcgca 170761 tcctggggct gtagtcggtc ccaagggttg ggctgttcgc ccattaaagc ggtacgcgag 170821 ctgggttcag aacgtcgtga gacagttcgg tccctatccg tcgcgggcgc aggaaatttg 170881 agaggagctg tccttagtac gagaggaccg ggatggacgc accgctggtg taccagttgt 170941 tctgccaagg gcatcgctgg gtagctatgt gcggacggga taagtgctga aagcatctaa 171001 gcatgaagcc cccctcaaga tgagatttcc cattccgcaa ggaagtaaga tccctgaaag 171061 atgatcaggt tgataggtct gaggtggaag tgtggcgaca catggagctg acagatacta 171121 atcgatcgag gacttaacca tatttttgaa tgatgtcaca cctgttatct agttttgaga 171181 gaacactctc aatttgtttg gtggcgatag cgaagaggtc acacccgttc ccataccgaa 171241 cacggaagtt aagctcttca gcgccgatgg tagtcggggg tttccccctg tgagagtagg 171301 acgccgccaa gcaattgcac attagtgtaa ttttttaaaa aagttattga ctttgaagaa 171361 gtgacattgt atactaataa agttgcttta acaaagcgga caaacaaaat gatctttgaa 171421 aactaaacaa gacaaaacgt acctgttaat tcagttttta aaaatcgcac agcgatgtgc 171481 gtagtcagtc aaactacttt atcggagagt ttgatcctgg ctcaggacga acgctggcgg 171541 cgtgcctaat acatgcaagt cgagcggaca gatgggagct tgctccctga tgttagcggc 171601 ggacgggtga gtaacacgtg ggtaacctgc ctgtaagact gggataactc cgggaaaccg 171661 gggctaatac cggatggtta gtttgaaccg catggttcaa acataaaagg tggcttcggc 171721 taccacttac agatggaccc gcggcgcatt agctagttgg tgaggtaacg gctcaccaag 171781 gcaacgatgc gtagccgacc tgagagggtg atcggccaca ctgggactga gacacggccc 171841 agactcctac gggaggcagc agtagggaat cttccgcaat ggacgaaagt ctgacggagc 171901 aacgccgcgt gagtgatgaa ggttttcgga tcgtaaagct ctgttgttag ggaagaacaa 171961 gtaccgttcg aatagggcgg taccttgacg gtacctaacc agaaagccac ggctaactac 172021 gtgccagcag ccgcggtaat acgtaggtgg caagcgttgt ccggaattat tgggcgtaaa 172081 gggctcgcag gcggtttctt aagtctgatg tgaaagcccc cggctcaacc ggggagggtc 172141 attggaaact ggggaacttg agtgcagaag aggagagtgg aattccacgt gtagcggtga 172201 aatgcgtaga gatgtggagg aacaccagtg gcgaaggcga ctctctggtc tgtaactgac 172261 gctgaggagc gaaagcgtgg ggagcgaaca ggattagata ccctggtagt ccacgccgta 172321 aacgatgagt gctaagtgtt agggggtttc cgccccttag tgctgcagct aacgcattaa 172381 gcactccgcc tggggagtac ggtcgcaaga ctgaaactca aaggaattga cgggggcccg 172441 cacaagcggt ggagcatgtg gtttaattcg aagcaacgcg aagaacctta ccaggtcttg 172501 acatcctctg acaatcctag agataggact gtcttcgggg gcagagtgac aggtggtgca 172561 tggttgtcgt cagctcgtgt cgtgagatgt tgggttaagt cccgcaacga gcgcaaccct 172621 tgatcttagt tgccagcatt cagttgggca ctctaaggtg actgccggtg acaaaccgga 172681 ggaaggtggg gatgacgtca aatcatcatg ccccttatga cctgggctac acacgtgcta 172741 caatggacag aacaaagggc agcgaaaccg cgaggttaag ccaatcccac aaatctgttc 172801 tcagttcgga tcgcagtctg caactcgact gcgtgaagct ggaatcgcta gtaatcgcgg 172861 atcagcatgc cgcggtgaat acgttcccgg gccttgtaca caccgcccgt cacaccacga 172921 gagtttgtaa cacccgaagt cggtgaggta accttttagg agccagccgc cgaagtggga 172981 cagatgattg gggtgaagtc gtaacaaggt agccgtatcg gaaggtgcgg ctggatcacc 173041 tcctttctaa ggatattata cggaatataa gaccttgggt cttataaaca gaacgttccc 173101 tgtcttgttt agttttgaag gatcattcct tcgaaacgtg ttctttgaaa actagataac 173161 agtagacatc acattcaagt aatacaagat atcacatagt gattcttttt aacggttaag 173221 ttagaaaggg cgcacggtgg atgccttggc actaggagcc gatgaaggac gggacgaaca 173281 ccgatatgct tcggggagct gtaagcaagc tttgatccgg agatttccga atggggaaac 173341 ccaccactcg taatggagtg gtatccatat ctgaattcat aggatatgag aaggcagacc 173401 cggggaactg aaacatctaa gtacccggag gaagagaaag caaatgcgat tccctgagta 173461 gcggcgagcg aaacgggatt agcccaaacc aagaggcttg cctcttgggg ttgtaggaca 173521 ctctgtacgg agttacaaag gaacgaggta gatgaagagg tctggaaagg cccgccatag 173581 gaggtaacag ccctgtagtc aaaacttcgt tctctcctga gtggatcctg agtacggcgg 173641 aacacgtgaa attccgtcgg aatccgggag gaccatctcc caaggctaaa tactccctag 173701 tgaccgatag tgaaccagta ccgtgaggga aaggtgaaaa gcaccccgga aggggagtga 173761 aagagatcct gaaaccgtgt gcctacaagt agtcagagcc cgttaacggg tgatggcgtg 173821 ccttttgtag aatgaaccgg cgagttacga tctcgtgcaa ggttaagcag aagatgcgga 173881 gccgcagcga aagcgagtct gaatagggcg catgagtacg tggtcgtaga cccgaaacca 173941 ggtgatctac ccatgtccag ggtgaagttc aggtaacact gaatggaggc ccgaacccac 174001 gcacgttgaa aagtgcgggg atgaggtgtg ggtaggggtg aaatgccaat cgaacctgga 174061 gatagctggt tctctccgaa atagctttag ggctagcctc aaggtaagag tcttggaggt 174121 agagcactga ttggactagg ggcccctacc gggttaccga attcagtcaa actccgaatg 174181 ccaatgactt atccttggga gtcagactgc gagtgataag atccgtagtc gaaagggaaa 174241 cagcccagac cgccagctaa ggtcccaaag tatacgttaa gtggaaaagg atgtggagtt 174301 gcttagacaa ccaggatgtt ggcttagaag cagccaccat ttaaagagtg cgtaatagct 174361 cactggtcga gtgactctgc gccgaaaatg taccggggct aaacgtatca ccgaagctgc 174421 ggactgttct tcgaacagtg gtaggagagc gttctaaggg ctgtgaagcc agaccggaag 174481 gactggtgga gcgcttagaa gtgagaatgc cggtatgagt agcgaaagag gggtgagaat 174541 cccctccacc gaatgcctaa ggtttcctga ggaaggctcg tccgctcagg gttagtcggg 174601 acctaagccg aggccgaaag gcgtaggcga tggacaacag gttgatattc ctgtaccacc 174661 tcctcaccat ttgagcaatg gggggacgca ggaggatagg gtaagcgcgg tattggatat 174721 ccgcgtccaa gcagttaggc tgggaaatag ggaaatccgt ttcccataag gctgagctgt 174781 gatggcgagc gaaatatagt agcgaagttc ctgattccac actgccaaga aaagcctcta 174841 gcgaggtgag aggtgcccgt accgcaaacc gacacaggta ggcgaggaga gaatcctaag 174901 gtgatcgaga gaactctcgt taaggaactc ggcaaaatga ccccgtaact tcgggagaag 174961 gggtgctctg ttagggtgca agcccgagag agccgcagtg aataggccca ggcgactgtt 175021 tagcaaaaac acaggtctct gcgaagccgt aaggcgaagt ataggggctg acgcctgccc 175081 ggtgctggaa ggttaagagg agcgcttagc gtaagcgaag gtgcgaattg aagccccagt 175141 aaacggcggc cgtaactata acggtcctaa ggtagcgaaa ttccttgtcg ggtaagttcc 175201 gacccgcacg aaaggcgcaa cgatctgggc actgtctcaa cgagagactc ggtgaaatta 175261 tagtacctgt gaagatgcag gttacccgcg acaggacgga aagaccccgt ggagctttac 175321 tgcagcctga tattgaatgt tggtacagct tgtacaggat aggtaggagc cttggaaacc 175381 ggagcgccag cttcggtgga ggcatcggtg ggatactacc ctggctgtat tgaccttcta 175441 acccgccgcc cttatcgggc ggggagacag tgtcaggtgg gcagtttgac tggggcggtc 175501 gcctcctaaa aggtaacgga ggcgcccaaa ggttccctca gaatggttgg aaatcattcg 175561 cagagtgtaa aggcacaagg gagcttgact gcgagaccta caagtcgagc agggacgaaa 175621 gtcgggctta gtgatccggt ggttccgcat ggaagggcca tcgctcaacg gataaaagct 175681 accccgggga taacaggctt atctccccca agagtccaca tcgacgggga ggtttggcac 175741 ctcgatgtcg gctcatcgca tcctggggct gtagtcggtc ccaagggttg ggctgttcgc 175801 ccattaaagc ggtacgcgag ctgggttcag aacgtcgtga gacagttcgg tccctatccg 175861 tcgcgggcgc aggaaatttg agaggagctg tccttagtac gagaggaccg ggatggacgc 175921 accgctggtg taccagttgt tctgccaagg gcatcgctgg gtagctatgt gcggacggga 175981 taagtgctga aagcatctaa gcatgaagcc cccctcaaga tgagatttcc cattccgcaa 176041 ggaagtaaga tccctgaaag atgatcaggt tgataggtct gaggtggaag tgtggcgaca 176101 catggagctg acagatacta atcgatcgag gacttaacca tatttttgaa tgatgtcaca 176161 cctgttatct agttttgaga gaacactctc aatttgtttg gtggcgatag cgaagaggtc 176221 acacccgttc ccataccgaa cacggaagtt aagctcttca gcgccgatgg tagtcggggg 176281 tttccccctg tgagagtagg acgccgccaa gcaagcttaa acccagctca ttgagctggg 176341 ttttttgttt tatatctgtg ccgatttgct ttcgtcagta tccattttat caagcttctg 176401 ctttttaaag ttttctaata cttttgaatt ccaatacaat ccctagcatg atcaacatga 176461 gagtcataaa taatcaaaat gcagtttgta cgggagactc atccagactc catccgactg 176521 cgattggcag gatagagccg ccaatccatt ggcagcgaac agcatgcttg tcgtttgttc 176581 tgtttttcca tgataaaatt gattggtgac aataaaataa tggcgaacat gccggccata 176641 aataagtcct aagaaaaaac taagaataat ccctgcaaaa gctgttttat tgattgccaa 176701 aatacagagt taaatgaggc cgctcatatt tatcagcctg agataatgat gataggttat 176761 tttttcggaa accagctcgg gttgccaaat gagagaaaag atattactgt cattaaaacg 176821 attcttggtt tcatccggat atgataaaat gtctcagact atatttgagc catttttttc 176881 ttcagcaatc atcttgcgta attgataaaa atttattatg atactctttg tatgacaact 176941 ccttgcctca atacaatata ctcaacgttt ccccgttttc tccggtcgtt tttcttttca 177001 ttttctcccg taaaataaaa aaagctccca atacaataga tatggtgcgg atttattttt 177061 tactaaaaag gagtcgttat atttgaataa tagttttaca ttaaaacagc aatggttcgg 177121 gaatatccga aaagacattc ttgctggcat tttagttgcg ttagcgttaa tacctgaagc 177181 gattggcttt tctattatag ccggtgtgga tccgatggtc ggtctttatg cgtcattttg 177241 catagccatt attatttcta tttttggtgg cagacctggc atgatttcag ctgcgacagg 177301 ctcaatggca gtcgttatgg tgtcgctggt tgctgatcat gggcttcagt atttatttgc 177361 ggctacgatt ttgacaggca ttattcaggt gattttaggt atcagtaaaa ttgcaagatt 177421 aatgaaattc atcccgcgtt ctgtgatgat cgggtttgtg aatgcgctgg cgatccttat 177481 cttctctgcg cagcttcccc agtttgaagg tgcttcttgg agcatgtatg cgatgcttgc 177541 cgggtcgttg gttattattt atgtgctgcc aaggtttacg actgctgttc cgtctccgct 177601 tgtggcgatt attgtgatga caattattgc ggtcactttc catgtggatg tgcggacggt 177661 tggtgatatg ggcaatattt ctagttcatt gcctcatttc ttaatccctg atgttccgtt 177721 tacctttgaa acactgcaaa ttatttttcc ttattcaatt gctttagcgt ttgtcgggtt 177781 gcttgaatct ttgctgacag cacagattat tgatgaaatg acggatacgg atagtgataa 177841 aaataaagag agccgcggac agggaattgc gaatatcgtg actggattct ttggcggaat 177901 ggcaggctgc gctatgatcg gacaatctgt cattaataca aaagcgggcg gtcgcggacg 177961 tttgtcagca tttgttgccg gtgcttttct gatgttttta attgcggtgt taagtcatgt 178021 cgtggtgaaa atcccaatgg cggcgttagt agctgtaatg gttatggtgt ctgtcggcac 178081 ttttgattgg tcttctttaa aaggtctcaa aaaagcgccg ctcacggact cgattgtcat 178141 ggttgtgact gtggttacgg ttgttgtgac ggatgactta tctaagggtg tatttgtcgg 178201 tgttctttta agtgccgtgt tctttgtagc aaaaatctcg aagctgaaaa tcgtttctca 178261 tgcagaggat caaaagctta gaacgtatca agtgaagggg caaatctttt ttgcgtcagt 178321 gactgatctt acgaatgcgt ttatatatca agaggatatt gagcgggttg tgattgactt 178381 aactgaagct cacgtatggg acgattctgg tgcggccgca cttgataaga ttgttgcgaa 178441 gtttaaggaa caaggcattg aagctgagtt aaaaggtttg aataaagcga gtaaatctct 178501 aatgaaacag atggcataaa atagagaagc ccagatgaat gagatctggg cttttttata 178561 taacatacac ttaagcagca ttgatataat agagagaaga gaaattttaa ataggggact 178621 tgcatatgat gcttcagaag ctgaaccgtg tattggggag agtgatgccg ctgttaacgc 178681 cgactagtgt ggtgctgggc gtgctgctgt ctcagttttt aaatgggtat gaatgggctg 178741 tgccttggat ctttgctttt attacgtttg caggcagttt gagcgcgaac tttcaatctt 178801 tgagacatgc attgtctcat cctctcccta tgattcttgc actattcgtt cttcatattt 178861 tcatgccgct ttttgcttgg ggcagcggcc atcttatatt taaaggtgat cctttgacga 178921 ttaccggttt aacattggct gttgtgattc ctacggggat tacaagcttg atttgggcag 178981 cgatgtacaa agggaatgtc ggtttgacac tttcgattat tttagttgat actgtgctgt 179041 caccgctaat cgtaccgctg agtctttcat tgctggccgg cgctcaggtt cacatggatg 179101 tgtggggaat gatgaaaggt ctgattgtaa tggtcgtgat tccttctttt ttgggcatgc 179161 tgtttaatca gatgtcatct ccagaaagaa ctgcgtttgt gagcagtgcg ctgtcgcctt 179221 tttcaaagct ttgcttgatg gcagtgattg cgattaacag ttcagcgatt gctccttatt 179281 tcaaatccat tgatttgaga tttgcaggaa tagctgtaac ggtattcttt atcgcgttaa 179341 caggttatgc cgctgcttgg ctgatcggaa aaatgatgaa aaggcggcaa gaggaaatag 179401 tctctcttat atttacggga ggcatgagga atattagtgc cggcgcagtt cttgccgtta 179461 cgttcttccc gtctcaggtt gccgttcctg ttgtgatcgg catgctgttt cagcagatat 179521 tggctgcttt gtttggctat atgctgaatc gttttgaatt aaaaccaatg ttgcagaagg 179581 cataaaaaaa ccgctcatag ggttgagcgg ttttttccgt atagccattc gagcgcgttg 179641 atgaactgtt tgcagaaata cttgtggtgg tgcaccgctc ctttttcaat tgaaagacac 179701 aactggtctt cagtgaagcc tttttctttt agactttgat gaacttgctt tgtttttttc 179761 agcatatgtc gctgaatgga ttgtttttca cggccttctt cactcccgat agacatgaaa 179821 acacgtgcag tgccgggctt taaagaagat atatgaatgg tttccgctgc gttctcgtac 179881 cagtatgaac ctgatataga gcctattttc ccgaacattg acggatattt taatatggcg 179941 aacattgaga tgaggccgcc taatgaggca ccgatcattc ctcttgactg cggttccctg 180001 gtgacgttcc agttttcttc gattagcgga atgaactggt tcgttatatc agacagatag 180061 tgatatccca ttccgccgaa gtccgtgaac cgatcactga gtgatgcagc cggccatggg 180121 gtgtattcat caagccggtt ttcgggttcg ataccgatca gcacgagttc agggagcctt 180181 tgctgttgaa aggcgctttc tagtaattcg atttggtttt ggaacaaaga actgccatcc 180241 tgcacgtaaa cagcaggaaa tcccccgctg tctgtgctgt aggaaggagg gaggtacagc 180301 gtgaacctcc tgttgccggc tttgtgttct gaaagagatc ctttcaagca ttctccccct 180361 ttttttgctt gaaaagcaga tataagaaat aaggaactcc gaggatcgcc aaaatgatgc 180421 ctgcgggcac ttctgcgggc tgaaaaaaca gttttccggc aaagtctgcg cttatcacaa 180481 gaagcatccc gattaaaccg ctcagtggca ggatatagcg atgttcgacg ccagccagtc 180541 tccgtgagat atggggagca attaagccga caaacgccat acttcccgct acggagacac 180601 aggcgctgat gattgctaca caggcaacga gaaggatggt tttttcttta tttgatgaaa 180661 taccgaggct tctgactgtg tcttcatcaa aacgaatggt gtcgagcagg cgggatttgc 180721 cgataagaat cggtataaac agcagcatcc atgggagtac agctgtaata tacgtccagt 180781 tggcagacca gatgcttccg tttttccaca ccatggccat ttgatagtct tgcgggtcca 180841 tttttaaaga taaaaacaaa gacagggcgc tgaatcctga attgatcgca atccctacca 180901 aaataattct tcctgaatct aaattgcctc tgtgccatgc aaatatgtaa atcaggatcg 180961 ccgcgatgag cccgcctatc aatccaaaga gcggcattcc catcgctgca gctatggatg 181021 tcacttcctt ctggccttgg aataagagca taaacgctac aatgccagct cctgcccctg 181081 cgttgattcc gagaattcca gggtcagcaa gcccgtttct cgtgatggcc tggataacag 181141 cgcctgcaat gccaagaccg agtccaataa tagcagccat gacaacccgc ggcagtctta 181201 aatcgaacag caaaatttca tactgcggat tcgggtcgat ttgaaaaaga gtggagagca 181261 gctcagcagg acgaacagaa aatgatccgc tcgttaagct gaaatagctg acaacaagaa 181321 tcaaagcgat gaacaatgca tattttttag ccattttgct cccctccttt tcgtttaatt 181381 aaataaagga agaaaggtac gccgataatg gatgttacga cctcaatcgg tgtttcaaac 181441 ggatagttga taaatctgct tgcgagatca cacagggtta aaaagattcc gcccaaaata 181501 caggaacacg gaatcagcct gctgtaatca gagccgacga gaaatctcgt gatatgcgga 181561 acaaccaacc cgacaaacgc aatttttccg gccagcgcta cggcactgcc ggttagaatg 181621 atgacggaaa gcatcgccat gattttaatg gtttttttct tttgccccag gcttttagaa 181681 atgtcgtccc ctaatgatac agcggttacc tttttgctga gagaaatggc cattataatg 181741 ccaatcagga aaaacggagc ggcaagcttc aggaaatctg gactcatttg atgaagtctg 181801 gcactgtacc agaaactgag atcctgagaa atttgaaaat aaatcgacat ggccgctgat 181861 aagctgctga gcagcatgct tgtgactgtg ccgatgatgg cgagctgcac gggggtaaat 181921 ccgtttggca tcatggcggc aaggccgaat actaacaccg ctcctaacgc tgagccgata 181981 aaagagtata tcatcatttc aatcgaagat gattgcggga gcagaaccat gcaaagcgta 182041 atgataaacg ctgaaccatc tgaaacaccc ataatggatg gcgaagctaa ataattgcgc 182101 gtaatgccct gcataagcgc tccagaaaca gcaagggctg cccctatgag cagagcgccg 182161 gcagcccttg gaatccggga atgccatata atttgatggt ctgtgtttcc cggatcgaaa 182221 tgaataagag atgtaaaaac aatatctgtg ctgagatgct ttgccccata aaggattgaa 182281 agcaaaagtg acagcgctat agcaaatgga gaagtaatca atatgatacg tgtccactgt 182341 tttgaataca tacaaaaacc tactctgaat tagttttgtg tcaatttttc agcagccgct 182401 ttcaggaaac ggactttgct ccaagctgtg ccgccttgtg cgagagggtc cactgagttg 182461 acatacacat ggtcttcttt gactgcttta aggcttttcc agattggatt tttctctaaa 182521 tcttttaagg catcaggttt gtctgcattt tcatcatcag aaaattggac gaaaatatgg 182581 tccgggttca tttcacttaa tttttctaat gaactcagct cttgcgcttt tgcagccttt 182641 acttcgttcg gcgccttaag gcctaaatca ccgtatagtg tggagttgaa atacacctgt 182701 tcagggtaaa tgtaaatgtt gccttgtctg attctgatga caagcgcttt tgaatctttc 182761 gctttatcgt tgatttttgt ttttatttct tttagatcct gttcatagtc tgcaataatt 182821 ttctttgctt ttttctcttt tccagtcagc tgggcaagaa gcatcatgtt ttccttccag 182881 tttgaagaga tatgagaaac tgggatcgtc gtgcctgctg tgctgatttt ttgcagcgtt 182941 ttttccggaa actttgttga agcaaggata acatctggct tcatttcaag aatcttttca 183001 atatttggct ccattttttc tccggttggt tcggctttat cagtgatgtc tttgaacata 183061 tcagggaatt tgccggagaa tgaaattgcg ccttgcggat gaacgtcaag caatttcgcg 183121 tcttccattg attcaacgct tcccgtaatg gcaattttgt ctgtcggtac agttacttca 183181 tatgttttat caaggtattc aattttcttc ttctcagatg ctgtgccgct tgccttgctg 183241 gcagttgatt catttttgct gccgcaagct gccgccgtca gcgcgagaag taagattaat 183301 aaggtaagag atatcttttt catctataga gcctcctgtt caattgataa ctattatcaa 183361 ttggaattat agagaatgaa cagatataac accatggaca aattcctgat ttatcatgga 183421 caatctccgg atagtaaaga aacagtttgc tgaacgatgc gttcgtgccc gcaagctgag 183481 tattcattcc acgggtcaag ggatagaaga taaacacggt tatctcgtac cgcgcttagg 183541 ttttgccatg cttctgtctg ctgtaattgc tggtagtaag ctatggtctc cggctcttta 183601 aaaagaaaaa gcatcataca gtcagcttgg taatttgcga tattttctaa cgaaatcgct 183661 tgttctgaag gtgtgtcagc cgttgttgcc gagctgaatc ctaaatcccc aaagaaaact 183721 tcgcggacac ttcggttatg agccagatag aagttttgct tatgcagcct caaaaagaga 183781 aaacgcagcc cttgaacgtg ctgaagtgtt tttttggcgg ccgttgtctg ctggtcataa 183841 tccgctagcc acttttctgc ttcggactcc tcctttaaaa atgaggcagt ttgcagaaag 183901 tgggttctcc agctttcttc tgaaggaagg tacatgactt ctgcgatgcg attcaggcga 183961 tcttgttctt ctggagaaat agaatccatg ctgacaatca catctggttc tgcctgtgat 184021 aacgtgtaca ggttttcttc ccacttttca ttaaaccggt atgcactgag ctggacgggt 184081 atatctgtcg aataatgctg atagtagtaa gacgtccatt tcggatgcag agcggccgca 184141 aaaggtatgt ggtgaagagg gatgagatgg cccattgtgc cccttccgta tgcggcgatt 184201 ttctttcggc gttttttcat atagcttgta ggtgaacagc ctgtatattt tttaaagatt 184261 ctgctgaaat aaaattcatc ttgataaccg gtttggtgtg cgatttcttt caatttgcag 184321 tttgattttg ccatgagccg ttttgccttt gtgattcgtg ttttcgtaat aaattctgtt 184381 acgctctgtc ctgtccattt tttaaagctt tcactgtagt gtttggcact gattcctgcc 184441 atttgcgaca gctgggcaag cgtgattttt gtatcggcat gggtttcgat atagtgtttt 184501 gttttttcga ttgctgaatg tgtatccgtt tgatcagata aactggcagt aaaaagatca 184561 taaatcaggc tttgtacttc aatcacacat tttagctgag aaagctgaga cgattcattc 184621 catagtgcgg caagctcttg aagccggact gcaagatttt cgatatgtga aacattcata 184681 agcttcagtt tggctaattc cgattctgtg cacggtgtga aaatatcttg cccggtttcc 184741 ttgatatagc ttagaagcct gattatacag gcatctatat gtccatcggc tgctggcgta 184801 aagccaaagg tctcgttagg cggacaaaca taaagtgtct ttttttgcag aggattggtg 184861 tttgttccga tcgaaatata gccgtttcct tttaaatgaa aaatcagcac gaatgaatcg 184921 gctaattgct gttctgagaa gagatcactt gtctttttta gatattcaat ttgtactggt 184981 tgataaatca ctgcattttg cacgagtaga ccaccttttc agaagctttc aattgataat 185041 cattttcaat aaaaattgta ccaaataaat gaaagttttc ctatataaag cgggtgggtt 185101 tttagcatga aaaaaaccct tacttatgtg taaaagtaag ggtctttcgt tcaataagaa 185161 tatgttacac gtgtaacata cgatgcttat gttctaataa atgagatact tttttcttgt 185221 tttgctgaat tgttggagtg ttttttcata gctgtttatg atgttctcaa ccgaagttcc 185281 attttcaatt tttgtcctga tccagccgtt gcctgccagt ttatcgaatg aacctgttga 185341 caggaactca aaatcctcag gatagagatc gtgtatggtt ttaatgactg aaagacccgt 185401 tttaacggct tcaaacttat ctctgtctgt cacatagagc tgcacaccgt ggcaaagcgt 185461 tccttgatgt ttagaaaacg tcggtgtgaa ggatgctgcc ctaaatgtaa cgcccggcaa 185521 atggaggctg tttaatgttt cttcaagttc tgtgcttttg ataaagggag ctccgatcaa 185581 ttcgaatggc tttgttgtcc ctcgcccttc ggatatattt gttccttcaa tcagcccggt 185641 tgcaggataa acaaatgtgc tttccaccgt cggcatgtta ggcgaaggga ggacgaaagg 185701 caatcgggta tcgtcaaaat ccatttttcg tttccagtgt ttcattttta ccactgtaag 185761 atcggcatca atactaaatt ctttgttgaa cagtgaagcc aattcgccta tcgtcatccc 185821 atgcttcaat ggaatgggat acaatccgac aaatgaggcg tattcaggtt ctaagattgg 185881 tccttcaata tgattcccgc cttgaggatt cggacggtcc agcaccataa atggaatgcc 185941 gttttcttta gcggcttcca ttgcgtatgc cattgtataa atgtacgtgt agaaacgggt 186001 cccgacatcc tgaatgtcaa acattagaat atcgacattt ttaagcattt ctggagtcgg 186061 ttttttcgtt tttccgtaga ggctgtatac gggaaccccg gttttttcgt caatgtaaga 186121 gcctacttcg tctccagcct gggcgtcacc gcggacgccg tgttcagggc cgaataaagc 186181 tgtcagtttg atatccgggt tctcgtaaag gatatcgaca ctgcttttta gagatgtgtt 186241 tactccggct ggattggtga tcagtccgat gcgttttccc ttgagctgtt ttttatagtc 186301 tggcaagagc gtgtctatcc cagtctggac tttaggtttt ttagctgttt gattctttga 186361 atcgggtgaa gcagaggcag cggttatcgt tccgaacatc atgagccctg tcagaaaagc 186421 gaatattgtt tttctcatgt gtccctcctt attaaagcgg tcttcccgtt ttgatattta 186481 atccgtagcc aagtgggtaa agggtgttcc ctggtttcgt gactgacgga atgtcaactg 186541 gaagtgtgcc tttaggtttt gcctggccga atatcgccat cactccggcc ggaatattag 186601 gttgaagata acggccattt gcgtatcctt taaagccata gactgcaatc agtgcttttg 186661 cttcttcgaa attggctgcg tcataggggt tgcgcaggct cattaagaca aatggtttgt 186721 tgtgctgcag tgcggctttc atgacagctc tcggaaacac ggtggcccat ttgcttgaat 186781 ctgatattgt gtcgtcgatg acaccgtcgt tgacgacagg gtcatttttg acgacatagg 186841 agccggtaat gatataatca gcctctttta cttgtttttc atgctcggtc ttaaatactt 186901 ggctggcaaa gttcattttg ctgagggata cgggtttgat tttctttcgc ttgatgagat 186961 cgtgaatggt ttgttcgatt gaagcagttt gttcttcgta aggtgccaca attaagattc 187021 ggctgccttt tttaggcttg aacggcaaag tgtgctgttc attttttaat acagttactg 187081 ctttttcagc taattttttc tctgctttca ggtgctgctt gcttcctacg atttttttgg 187141 ctttggctat tttttctttt gtactgtcgc tgtttcgcgc tggatacatg ccgcgtttta 187201 ttttcaggga aatgattctt tcaactgaat tgttgatttg ttgttcagga atatccccgt 187261 ttttcacggc ttctttcaaa gcttgaataa cacgtgcgaa tttctgttct tctttcaatg 187321 aagtgactga ggctggcatt aatgcaatat cgacaccagc ttttacggcc atgaccacag 187381 cctcttcctg tccgaaatga tctgcgattg ccttcatatt gagcgcatcg gtaacgatga 187441 ccccattaaa gcccatttcc tgacgaagaa gacctgtcat cacttttttt gaaagtgtag 187501 ctggaaccag aatgtccgat ccatcgagtt tgcttttgta agtggtgtca tcaaaggcgg 187561 gaaactgaac atgggctgtc atcaccatat cagcaccagc atcaattgct ttttgaaaag 187621 gataaagctc gacctcacga agccgttctt ggccatggga aacgagcggc agtccataat 187681 ggctgtcaac gtccgtgtct ccatgtcccg ggaaatgttt gagggcagac gcgatatcct 187741 gccgctgcaa ccctttcatc gtatataaac cgaggcgtga tgtcagttct cgattggagc 187801 tgaatgaccg tacgccgatt acaggattat caggattatt gttaatgtcc acgacagggc 187861 tgaaatctgt attgatgcct aaggcagaga gctcttttcc gatgatgctg ccggtctgat 187921 acgcattgat tctgcttctg gctgcgccca gcgccatatt ccctgggaaa ttagtgccct 187981 cccctaacct cgttacaatg ccgccttcct gatcaatact cagcatgagc gggatttttg 188041 gacttgcctt ttggtaatcg tctgtcagtt ggacagtttg ttttgttgtt tttacatttt 188101 ctgcaaaaag gatgatgcct ccgaattgat atttcttgac gaggctggcg acttcatcat 188161 tcatttttgt aagggcttgc ggagaggact cgccttcctt ttgccaattt ctaaaatcag 188221 gcatcagcat ctggccgagt ttttcatcta acgacatacg attgacaatc tgattggcat 188281 cgattgcacg tttggatgca gaggcttctg tctgtctggc cccgaaaaag catgaaagaa 188341 agagaacggc tgaaaggata agcggaaaga caggtctcat agaaacttcc tcctatcgtc 188401 taatcattca ctccatcgct tcataaatcg cggttatgac acttccataa ctgcctgttg 188461 gaaattggtc accttcaaag acgttcggat tttcttccgg atcaataact ggtgtatgct 188521 ttttatttgt taacaatgcg atgcctaaat tgtatgctgg atcaataatt gtaactgtcc 188581 ccgtccagcc ggtatgcccg taagcatttt cgctggcatg agggccaaac atccattcca 188641 tgcttttact tccgttccgc ctccagccaa gagcgaatgt cggatctgtt gctgaaggtg 188701 ctgtaaacag gtcggctgtt ttctgatcaa ataaagaaat gtttcggtat gaacctttgt 188761 ttaacatgac ttgcagcagt atggccatat catctgcatt tgagaacaat ccggcatgcc 188821 cagacacgcc gtccattgag taaaacgctt tttcgtcatg cacctctcct tgcagcgtgt 188881 ttgtgcggat gttagggaat tgaataacgc cgtcacgtgt attgcccatg cgttcagtag 188941 ctgcgaactg tttcggttta aagccctttt gcagcggatt gtacaaggta tgcttcagcc 189001 tgagcggttt gtagagctct tgctccgtgt agacatcaag cggtttgccg gtgagttttt 189061 cgacaataca tccgagtagc atatatccaa tgtcactgta tacgtgtttt gtcccggttt 189121 gataatcgag cggaattttc gtcaaatatt caatcgtttt gtcccgttct tgggaatagt 189181 acttgccggc tttttccggc gtgtaaaagt aaaagcttga tgggagccct gattggtgct 189241 ggaggacatc aatgacacgt atcttgtctt ttccttttat gaggtcaccc ggctgatcct 189301 tgaaacccgg caaatatgca gaaacttttt catagacgtc aagttttcct tggctgacta 189361 agcgctgcaa tgcaaaattt gttgcgtaca tttttgtatt tgaggctaag tcaaacatcg 189421 tgcgggtttt cattttggcc ggacggcgca gcagttctga tccttcgtac tttttactgt 189481 agccgtatgc tgcttttttt atgatgcgtc catccttcac caccacaaga acggcgcctg 189541 gaaatcctgc tgcaatatcc cgttctatca tctgatctac cttccttagc ttcttcgtcg 189601 agaattgtgc agtttctgca tttatgattt tcggctcaat caagttgcct gctgtttgtg 189661 cgaaggtttc atttggcgca aatatcgata gggttaaaat ggcactgaat atgaacagtg 189721 tctttgtttt cacaggctag cccctttctg tgcttctatc ccgtttacta tccctaaaac 189781 agaaacaatt taatcgaact gagaagccat ttcatcttta tatccgaatg cataggtcaa 189841 taaaaaaccg gccgcgtagg aaataaagag cccaacgata tacaggatga tttgcgaagg 189901 caggactaga aaagatagcg gcagtccgga gacaccaatc gcaatggtgg ctacttgaaa 189961 ataagcttga aaggcgccgc cgattccagc tcctaaacat gctgttaaaa acggacggcc 190021 aagcggcagc gtgactccga aaataagcgg ttcaccaatg ccgagcagtc ccgatggaag 190081 cccgccggcg attgctttcc tcagtgttgt ttttttcgtc ttcacgaaaa cggcaaaggc 190141 cgcgcctacc tgtcctgcac ctcccatagc caaaataggg agcagaggat cattgccaat 190201 tgaattgatc agttccatgt gcacaggcgt caagccttga tgcagtccgg ttacgacgag 190261 aggaaggaag gttgcgccca gaataaagcc cgcagcgatg ccgccgatgt ccaggatgga 190321 cagtaggccg gatgtaatag catcagaaat gaatccgcct aaaggcataa atacgacata 190381 cgttacgatt ccggtgatta acagtgaaac ggtgggtgtg acaatgatat caagtgattg 190441 aggaataaaa cggcgaataa attgttcggt gtaagcaatg aatatggctg cgaaaaggac 190501 gccgatcaga cctcccctgc ccgggagaag ctcttctcca aataaactga tttttgcgat 190561 ctccggattg ataatcaaga tcccggccaa agccccaagt gcgggtgtcc cgccaaattc 190621 tttcgaagcg ttaataccga cgagaatgcc gagataagtg aacagccctg atccgatgac 190681 tgtcaggata atcgcaattt gtgagtctgc agagagccag cctgcttgaa taattgcttt 190741 ggtaatccca gtaattaaac cggaagcgac tagagcggga ataagaggga taaaaatgct 190801 ggcaatttta cgtaagaaaa gtttaaaagg agtggcattt ttccgattga tatcggcttt 190861 ctttttggcc gctgcttctt tgacatcggc accttcttct gctgacacga gctttgagaa 190921 agcagctgta acatgattga caactcctgt gccgaggata atttgtaagg tttcagcttc 190981 aacgaccccc aatacgccgt caagctttct taaagcctga gcatccgctt tgctttcatc 191041 gtaaggcgta atgcgcaggc gtgtcatgca atgcgtatat gaagaaatat tggattttcc 191101 tccgcatagc tcaaggattt tctgtgcgag atgatggtag ttattttctt tgctcattaa 191161 aacccctccc cttcaagatg ccttatttta ttctcataga ttgtatggct gctctcgttt 191221 tatctatata accggttgtc gtttcatact gctcagccgc catgcctaaa aacaaaacat 191281 caattataaa aagctgggcg aggcgggaag aagtggctgc acttcgaatc aaggcttcat 191341 tggaatgggc tgtatacaaa gggacatcag ccagtgcgga gacggatgtc tgactgaatt 191401 gtgtgaggct gatcgttgtg atgccttttt ccttagccat ggcgaacagt tcaacgattt 191461 cctgtgtctc tcctgaaaac gaaatggcga atacgatgtc gtctttatct gcatttgcga 191521 ttaaagatgc cacaagatga gtgtctgtaa acgcggttgc ttgtttatga atgcgaagcc 191581 acttttgctg ggcgtccttg gcgacaatgc cggaagcccc gaggccgata aaatgcacgg 191641 tatgagcttt gagaagcaga gaaaccgctc gttcaagctc tttgtagtcc atcaggtctg 191701 aagtatcctg aatggcttga atggcattgc cggccgtttt ttcggaaatg gagggcagcg 191761 gctcgtgggg aacaatatcc cggtagccct gaaacgtagg ctttgccaga tcgcctgcta 191821 ctctcatttt taaatcttga aatcctttta aaccgagtga tttgcagagc ctgatgacgg 191881 cagcgtcact tgaattggct aaggcgctga tttcgttgac cgtgctttcg attgctttgt 191941 ggggatgggc taggatataa tctgcaagtt tgcgctcgga tggagggagc ttatgcttca 192001 ttgattggat gatcgctaaa ccgcctgtgg ccattctagt tctctcctta tcatggatgg 192061 taatgttcga ttgctttgtc aatgaaaccg tttgcttcat cgagtaatgt ctgtgcttgt 192121 ttctgatctg tgcttgtttt gagcatgacg attgctgttt tgacgtgatg atcggcttgt 192181 tccagagtgt atctggctgt gtcgtatgaa gcgtttgtaa ggctttggat gatgctgatg 192241 gcgcgttctt ttagtttttt gttgctgacg ttgacgtcta ccatcaagtt ttcgtaaacc 192301 ttgccgattt tgaccattac agcggtagat atcatgttta gaatcatttt atgagcggtt 192361 gcggctttca tacgtgttga tcctgtaatg gcctcaggtc cgacgacaac ctcaatgctg 192421 tgatccgcat ccttgctgat ggcggaattt tcattgcaag taagggcgat ggtgtgtgct 192481 ccgactttac gggcgtatct tagggcgcct gcggcgtagg gtgtgcggcc gcttgctgcg 192541 atggcaatga cggtgtcatt tgaagtgagc tgtatgtttc ttaaatcttc agctcctgct 192601 tcttcactgt cttcaatgcc ctctgctgcc tgtaaaaagg cttcggggcc tccagccatg 192661 attccgatga cctgatctgg gcttacgctg taggtgggag gacattcaac agcatccatg 192721 acgccgagtc tgccgcttgt gccggcgcct gtatatatga gccggcctcc attttgaaac 192781 gattcatatg cgcagtctac agctgttttg atgtcgggga gaacctcctg aacggctgca 192841 gcgactttca tatcttcgtt gttgatcatt ttaaggatgc cgagagtgtt tgctttgtgg 192901 atttcaactg tttgactatt gcgtgattcc gttgtaagac ggtgaaggtt taatggttct 192961 gacatgagga tgccccctgt tttaaaatga tatatctcaa tattcagtat attcatttct 193021 gttatgatat ttcaactatg tttttaaatt tttgaaattt tatttcactt aagactataa 193081 gaaatgatga aggatcaact gttctccaag cggcccgatt cttcgccgtc ctttatcaag 193141 gaacccgctt ttcatataaa ggtgttttgc gcgtatgttc agatgattga cggccaagat 193201 gatttcgtcg caccatggaa aatatccgct cacaaaagcg ggaagcaaaa gcatggcttt 193261 tttcgcatag ccttttccgt gatgcacagc ggttaaagac agggagctga gcagtaaagc 193321 aaatggattg ttagaatagg aagcaagcgt ttcttttgat gcatgtaaaa tgaaaaaacc 193381 gactggaagg tcgtctttta agatgacaac cgggtatcgg tcctgtatgc ccagagcctg 193441 agacagcacc tctttcggga gggaggtaaa gcgtttgtca tcgttggtga gcgtgaatga 193501 ttggagctcg ggcaagtgtt caggcttata gaaggataaa gaaatgtctt gagtcatggg 193561 gtggcctcct tacaatatgt cgttaagctc gttttccgaa atgacgcggt agcccgcttg 193621 ttttaacagt gcggcggtta ctccgctgcc ggtgattttt ttgccagaga atgtgccgtt 193681 atagataaaa ccgcttccgc aagatggact gttttctttt aatatgacgg cagaagcgtt 193741 gatttctttt gcgtaagcca atgttttcgc ggcgccttcc atatatagtt ctgtgacgtc 193801 ttctcctgaa gctgtcacga ttttcgctgt tccattgagg acatcctcgc cagtgcctcc 193861 tatgatttct gcgggttcgc gtggggtaga gaagccgccg agaagttcag ggcaagccat 193921 gactgctttc ttttcatcga ctagttttct gattttctcc gacgctgcgt gagagccgtt 193981 atatctgcat tcaatgcctc caaggcaaga actgactaga atcatattgg tttctcctct 194041 cttgctttgc ttgtctctat cataaaataa atggctttag ttgggaggct ttttcagtta 194101 aaaaaggagt taaaaagttt gaaaataaaa aatttaattt tcctctttac aaacaggggg 194161 tgacctgtat ataataactt ttgtcagctc gacgagaaca caacggcccg ttggtcaagc 194221 ggttaagaca ccgccctttc acggcggtaa cacgggttcg aatcccgtac gggtcaccat 194281 ttggaggatt agctcagctg ggagagcatc tgccttacaa gcagagggtc ggcggttcga 194341 gcccgtcatc ctccaccatc ttgccggtgt agctcaattg gtagagcaac tgacttgtaa 194401 tcagtaggtt gggggttcaa gtcctcttgc cggcactgtt ttttcaaaat tttatgtgga 194461 ggggtagcga agtggctaaa cgcggcggac tgtaaatccg ctccctcagg gttcggcagt 194521 tcgaatctgc ccccctccac cattattggg ctatagccaa gcggtaaggc aacggacttt 194581 gactccgtca tgcgttggtt cgaatccagc tagcccagtc acagacacct ttgatcaaaa 194641 ggtgtctttt ttcttttcgg aaaaatcatt ccaacttcta actgttcagt ctgtataata 194701 attttaaaaa tatgttaagg tagtttattc acgaattacc atctacaccc tgccaaaaat 194761 ttgataaact tattttataa aaaaattgaa accttttgaa acgaagctcg tatacataca 194821 gaccggtgaa ggcagaggtt agataaatat ggaaatgatg attaaaaaaa gaattaaaca 194881 agtcaaaaaa ggcgaccagg atgcatttgc ggacatcgta gatatttaca aagataaaat 194941 ttatcagctt tgctaccgta tgcttggcaa tgtgcatgag gcggaggata ttgcacagga 195001 agctttcatc agagcgtacg ttaatatcga cagttttgat attaaccgga aattttcaac 195061 ttggctttat cgaatcgcga ccaatttgac cattgaccgc attcgcaaaa agaagccgga 195121 ttattacctc gacgcagagg tggctggtac ggaaggcttg accatgtatt ctcaaatcgt 195181 cgcagatggt gttttgcctg aagatgcagt tgtatcgctg gagctctcaa acacgataca 195241 gcagaaaatt ttaaagcttc ctgacaaata cagaacagtc atcgtattaa agtatattga 195301 cgaactctca ttaattgaaa tcggggagat tctaaacatt cctgtgggga ctgtgaaaac 195361 gcggattcac agaggcagag aggctcttag aaaacaatta agggatcttt aagtggggtg 195421 atgaaatgag ctgtcctgaa caaattgtgc agcttatgca tatgcatctt gatggagata 195481 tccttccaaa agatgaacac gtattaaatg aacatctgga gacatgcgag aaatgcagaa 195541 agcattttta cgagatggag aaatccatag cgctcgtacg gagcacatcg catgtcgaag 195601 cccccgcgga ttttaccgct aatgtcatgg caaaattgcc taaggagaag aaaagagctt 195661 ctgtaaaaag atggttcaga acccatcccg ttatcgcagc tgctgcggta ttcatcattt 195721 tgatgggcgg gggttttttt aacagctggc ataatgacca caatttcagc gtgtccaagc 195781 agccgaatct tgtggttcat aaccatactg tgaccgtgcc agaaggtgag acggtcaaag 195841 gtgatgtcac tgtcaaaaac ggcaagctga ttattaaagg caaaatagac ggggatgtaa 195901 ccgtcgtaaa cggcgaaaag tatatggcct ctgctggaca agtcaccggt cagattgaag 195961 aaatcaatca gttattcgac tggacatggt acaagatgaa gtctgcgggg aaaagtgtac 196021 tcgatgcatt caatccgaac ggagaagagt aaagcgcgtt agccgctttg ctcttttttt 196081 gcgggctgag agggctggca catttcactt gctaaatcga aatgtggtat aatgggctcg 196141 ctatgtaaag tacatatgcg taacacgtaa aacacaaaat acgaaatgac tgaaatcttg 196201 gaggacgagg aaatggcttt tgaggatatc ccttttttgc agtacctcgg caatgccgtt 196261 gatattctcc ttgtttggta tgtgatatat aaattgatta tggtgatacg cggcacgaaa 196321 gcggttcagc tgttaaaagg aattgtagtc atcgtgcttg ttcgtatggc cagccaatat 196381 ttgggcctca gcacacttca atggctgatg gaccaagcga taacatgggg atttttagca 196441 attattatta tttttcagcc tgagctgaga agagcgcttg aacagctagg ccgcggccgc 196501 tttttttcga ggagcggcac gcctgttgaa gaagcgcagc agaaaacgat tgaggccatt 196561 acaaaagcaa tcaattatat ggcgaaacgc cgtataggcg ccctgctgac cattgagcgg 196621 gatactggaa tgggcgatta tattgagacc ggcataccac taaatgccaa agtcagctct 196681 gagctgctga tcaatatttt tattccaaac accccgcttc atgacggtgc ggtaattatg 196741 aaaaataatg aaattgccgc ggccgcctgt tatctgccgc tttctgagag cccgtttatt 196801 tcaaaagaac tgggcacgcg gcacagagca gctgtcggta tcagtgaagt aacagacagt 196861 ttgacgatta ttgtgtctga agagaccggc ggcgtcagtg tggcaaagaa cggcgacctt 196921 cacagagagc ttacagaaga agcgctgaaa gaaatgcttg aagccgagtt taagaaaaac 196981 accagagaca cttcttctaa ccgctggtat tggaggggca agaaaaatgg ataaattctt 197041 aaacaaccgc tgggctgtga aaattattgc tctgcttttc gcgctcttgc tttatgtggc 197101 ggttaacagc aaccaagcac cgactccaaa aaaaccgggt gaatctttct ttccgacatc 197161 aacaactgat gaagcaactc tgactgatat tccggttaaa gcgtattatg atgatgaaaa 197221 ttacgtcgtg acgggtgttc cgcaaacggt taatgtcacg ataaaaggct cgacaagcgc 197281 cgtgaaaaag gctcggcaga ccaaaaactt tgaaatatat gccgatatgg aacatttgaa 197341 aaccggcaca cataaggttg agcttaaggc caaaaacgtg tcggatgggc tgacaatctc 197401 aattaatccg tctgttacga cagtgaccat tcaggaacgg acgaccaaaa gttttcccgt 197461 agaagtggag tactacaaca aaagcaagat gaaaaaaggc tattctccgg agcagccgat 197521 tgtcagtccg aaaaatgtgc agattaccgg atcgaaaaat gtgatcgata atatttctct 197581 tgtaaaagct tcagtgaatt tggaaaacgc agatgaaacg attgaaaagg aagcgaaagt 197641 gactgtctat gataaagacg gaaacgcgct tcctgtcgac gtggagccct cggtcatcaa 197701 gattaccgtt ccggtgacaa gcccgagtaa aaaagtgccc tttaaaattg aacggacagg 197761 aagccttcct gacggtgtca gcatagcgaa tattgaatcc agccccagtg aggtaacggt 197821 ttacggctca caggatgtgt tggattctct tgaatttatt gacggcgtca gcctagattt 197881 aagtaaaatt aacaaggatt ccgatatcga ggcagatatt ccgcttcctg acggtgtcaa 197941 aaaaatctca ccgtcaaagg tgactttgca tatagaagtc gatagtgaag cggatcagaa 198001 gttcgagaat gtccctatca agactgtagg gctgagcagc tcacaaaaca ttgaatttct 198061 tgatcctgaa tcacaagcga tagatgtaac ggctaaaggc tctcccacga atataaataa 198121 actgaaaaaa tcagatattg aattgtatgt gaatgtttca gatttagagg acggggagca 198181 tagcgtgaag cttgaagtga acgggccaca gaatgtaact tggtccttgg ggcggaaaaa 198241 cgccaaaatc aagctgacgt ctaagaaaag caatacatca acgaatgata acagcagcaa 198301 tacatcaggg aaccaggaca cagataaaca aacaaatgat caaaagaaca atcagcaaga 198361 agatacaaag aacactgata aaaacaacaa cgatcaaaac caagacggaa ataaagatca 198421 aaaccaagat caggatgagg atgaatccac tgcgaattca caatcctcat cggaataaaa 198481 aaggagcgat tataaaatgg gcaagtattt tggaacagac ggtgtaagag gtgtcgccaa 198541 tagtgagctt acacctgagc tggcctttaa agtcggacgt ttcggcggtt atgtgctgac 198601 aaaagacaaa caacgtccaa aagtgctgat aggccgcgat acacgcatct ccggccatat 198661 gctggaggga gcccttgtcg ccggactttt atccattggc gcagaagtca tgcgcctggg 198721 tgtcatttct acaccaggtg tatcttattt gacaaaagcg atggatgcag aggcgggcgt 198781 catgatttcc gcttctcata acccagtgca ggataacggc atcaaattct ttgggggaga 198841 tggatttaag ctttctgatg aacaggaggc tgaaattgag cgcctgatgg acgaacctga 198901 ggataagctg ccaagacctg tcggagcaga ccttggactt gtaaacgatt attttgaagg 198961 cggacaaaaa tatctgcaat tcttaaaaca gacagctgat gaagatttca caggcattca 199021 tgtggcattg gactgtgcca atggcgcaac gtcatccttg gcgacacacc tgtttgctga 199081 tttagatgca gatgtttcta caatggggac ttccccgaac ggattaaaca ttaatgacgg 199141 cgtcggttcg actcatcccg aagcgctcag cgcgtttgtc aaagagaaaa acgcggatct 199201 cggtcttgcg ttcgacggtg acggcgaccg cctgattgct gtcgatgaaa aaggaaatat 199261 tgtagacggc gaccaaatca tgtacatatg ctcaaaacat ctgaaatcag agggccgttt 199321 aaaggatgat acagtggttt caaccgtgat gagcaacctc ggcttctata aggcgctcga 199381 aaaagaaggc atcaaaagcg tgcagacagc tgtcggcgac cgctacgtag tagaagcaat 199441 gaaaaaagac ggctacaacg tcggcggaga gcagtcagga catcttattt tccttgatta 199501 caacacgaca ggggacggat tattgtctgc tattatgctg atgaacactt taaaagcaac 199561 aggcaagccg ctgtcagagc ttgcagctga aatgcagaag ttcccgcagc tgttagtcaa 199621 tgtgagagtg actgataaat ataaagttga agaaaatgaa aaagtaaaag cagttatttc 199681 tgaagttgaa aaagaaatga acggcgacgg ccggattttg gtgcgccctt caggaactga 199741 accgctcgtc cgtgtcatgg ctgaagcgaa gacgaaagag ctgtgcgatg agtatgtcaa 199801 tcgcattgtt gaagtcgtcc ggtcagaaat gggattagag taacgaagtc tattatcaga 199861 gagtgaacaa gacaagcgag gtttacataa gataattgtg agacatacgg caaagttgct 199921 taaaaaacaa ttgaccgttt atgccacatg ttgtaaaatc aagcttgtct tgttcttatt 199981 ttctcaatag gaaaagaaga cgggattatt gctttaccta taattatagc gcccgaacta 200041 agcgcccgga aaaaggctta gttgacgagg atggaggtta tcgaattttc ggcggatgcc 200101 tcccggctga gtgtgcagat cacagccgta aggatttctt caaaccaagg gggtgactcc 200161 ttgaacaaag agaaatcaca tgatcttcca aaaaacatgt aggaggggac gattgaaagt 200221 ccccttgaaa tttgactttc ttcgtctcct tttacaatct taggaggaag aaaaatatgt 200281 gtggaatcgt aggttatatc ggtcagcttg atgcgaagga aattttatta aaagggttag 200341 agaagcttga gtatcgcggt tatgactctg ctggtattgc tgttgccaac gaacagggaa 200401 tccatgtgtt caaagaaaaa ggacgcattg cagatcttcg tgaagttgtg gatgccaatg 200461 tagaagcgaa agccggaatt gggcatactc gctgggcgac acacggcgaa ccaagctatc 200521 tgaacgctca cccgcatcaa agcgcactgg gccgctttac acttgttcac aacggcgtga 200581 tcgagaacta tgttcagctg aagcaagagt atttgcaaga tgtagagctc aaaagtgaca 200641 ccgatacaga agtagtcgtt caagtaatcg agcaattcgt caatggagga cttgagacag 200701 aagaagcgtt ccgcaaaaca cttacactgt taaaaggctc ttatgcaatt gctttattcg 200761 ataacgacaa cagagaaacg atttttgtag cgaaaaacaa aagccctcta ttagtaggtc 200821 ttggagatac attcaacgtc gtagcatctg atgcgatggc gatgcttcaa gtaaccaacg 200881 aatacgtaga gctgatggat aaagaaatgg ttatcgtcac tgatgaccaa gttgtcatca 200941 aaaaccttga tggtgacgtg attacacgtg cgtcttatat tgctgagctt gatgccagtg 201001 atatcgaaaa aggcacgtac cctcactaca tgttgaaaga aacggatgag cagcctgttg 201061 ttatgcgcaa aatcatccaa acgtatcaag atgaaaacgg caagctgtct gtgcctggcg 201121 atatcgctgc cgctgtagcg gaagcggacc gcatctatat cattggctgc ggaacaagct 201181 accatgcagg acttgtcggt aaacaatata ttgaaatgtg ggcaaacgtg ccggttgaag 201241 tgcatgtagc gagtgaattc tcctacaaca tgccgcttct gtctaagaaa ccgctcttca 201301 ttttcctttc tcaaagcgga gaaacagcag acagccgcgc ggtactcgtt caagtcaaag 201361 cgctcggaca caaagccctg acaatcacaa acgtacctgg atcaacgctt tctcgtgaag 201421 ctgactatac attgctgctt catgcaggcc ctgagatcgc tgttgcgtca acgaaagcat 201481 acactgcaca aatcgcagtt ctggcggttc ttgcttctgt ggctgctgac aaaaatggca 201541 tcaatatcgg atttgacctc gtcaaagaac tcggtatcgc tgcaaacgca atggaagctc 201601 tatgcgacca gaaagacgaa atggaaatga tcgctcgtga atacctgact gtatccagaa 201661 atgctttctt catcggacgc ggccttgact acttcgtatg tgtcgaaggc gcactgaagc 201721 tgaaagagat ttcttacatc caggcagaag gttttgccgg cggtgagcta aagcacggaa 201781 cgattgcctt gatcgaacaa ggaacaccag tattcgcact ggcaactcaa gagcatgtaa 201841 acctaagcat ccgcggaaac gtcaaagaag ttgctgctcg cggagcaaac acatgcatca 201901 tctcactgaa aggcctagac gatgcggatg acagattcgt attgccggaa gtaaacccag 201961 cgcttgctcc gttggtatct gttgttccat tgcagctgat cgcttactat gctgcactgc 202021 atcgcggctg tgatgtggat aaacctcgta accttgcgaa gagtgttact gtggagtaat 202081 aaatgtttaa cccctttgga taagattatc taaaggggtg tttttatgtc caaaagcgaa 202141 agaacgtcta cagtggaaaa atggattaaa gaagttgatg gtacaggacc cgactatcga 202201 tcgaccatgg ctatagattt aagatgtttc ctcattagat cggtcaatca ggttaaaagg 202261 cattaaaact tggagagaaa ctgcttttgc ctaactgagt tttctaatgt taatacagat 202321 ataagagagc agttcctcat taagatacgc ttttgatagc agttggaatt tagcatgcta 202381 gaaatccgaa aaccggagag cctattggaa tgataacgtg tttttttatt gacaattaat 202441 aaagggcaaa gaattctaga agtcgcactt acaatgtact tgtgggatta ggttttaaag 202501 ttcattcttt ttttattgag tacattccgg ttaaagttga aatgattcag taaaggacac 202561 gccataaata aaaggtagcg tatgattgcc attctttcca tggaaccgat atttctaaga 202621 tttcatcttt cgtaggcttt cggttcatat tacgtaatat ttttatcgaa tgaataagac 202681 ccacatcatc gattggaaaa gctgtcggga acctaaggca gcgcattaga acataattgg 202741 ctgtccaagg accgattcct cgtattttaa ttaagttttt ttcagcatct ttaaagttca 202801 ttttcattaa tttttccctc gataattctc cacttgccat taatctggct attccaatga 202861 tatattcact ttttttcacc gtcattttaa tatctgccag gtcggtaggg gttaaccgtg 202921 caattcgctc gtacggtggg aacacccaat actttttacc attccattca atagaatcgc 202981 caaatgcttc tacaaattgc ttctttaagg agtacgcgaa ggctaagtta atttgttgcc 203041 ctaaaactcc ccaacataaa gcttcaaata aatcgggaat gccgatcact cgcaacccat 203101 aaaattttcg ggcaggcatt ttaagtaatg gatctgcttt tgccatttca taaaatggag 203161 ttaaatcgtt atcaagatca aaccattcat gaatatattt tacaatctct tcccgtttcc 203221 actgctcaac aggtctagaa tcgtttagga attgaacaat catttgttta ttattgatta 203281 cgcttacctg cactaaggac cgaatttccc caatggctat aacttttgta atgatattgt 203341 tctctatttc atacatgcat tcattttttt ccctggttag gtagccaagg ttcgcattca 203401 tgtcgaaaat ttcaggtaat gtaatgacaa taacatcatt gacttcatgc catgtcactt 203461 tttcattctc cttatcttaa ataattataa gaaaactcac gctggttgaa attagtttat 203521 cacataatca tctttactca ttttgttatc ttgctattac attctaacca ccttattttt 203581 ttctatttat gaggttatag tgtagttatc aagaatgcta aacgggagta gataaaaatg 203641 gcccaagata taaaaaacgc gtgtcgaaaa tttaaattgg gattcaattc aaagaattag 203701 atgagcattg taaggagagg tgagataaat gccggatagt atcaataacg gacataaaga 203761 gagccatgat catagaattt cgaatgatgc agaaatgata acagatgaaa agtggcaagc 203821 aattataaat aatgatgcag cgtacaataa tcaatttttc tacgctgtta aatcgacagg 203881 gatattctgt aaaccatcct gtaaatctcg cgttccgaaa aaagaaaatg tatgtatctt 203941 tccaaacaca gaacaagctc tccgcgcaaa ttttcgccct tgtaaacgtt gcaagcccac 204001 taatgaaaaa atgcctgata gcgagtgggt tgatttaatt actgaataca ttgataaaaa 204061 tttcacagaa aaattaacgc tagaatcgtt agcagatatt tgtcatggga gtccgtatca 204121 tatgcatcga acatttaaaa aaattaaagg cattacgctg gttgagtata tacaacaagt 204181 tagagtacac gcggctaaaa agtatttgat tcagacaaat aaagcgattg gagatatcgc 204241 tatatgtgtg ggtatagcta acgcgcctta ttttattact ttatttaaaa agaaaactgg 204301 acagacacca gcacgatttc gtcaaatgag taaaatggag gaaacgtaca atggaaacaa 204361 ataaaccaac cctttattgg tctttactaa tgttcaagga ttggaatttt tatattgctt 204421 caactttaaa ggggcttgtg tttgtaggtt cacagaacaa accaatcgag gaattgttcg 204481 aatgggctag gaaacgcttt ccgggaagtc ttcttgttga agatgatgat aagcttgaac 204541 cctatgccgt tgaaatcact caatatctag aaggaaagcg gaaaaacttt actgttccag 204601 ttgagtacgc cggtacgcaa tttcagctag ccgtctggaa tgcactttgt gaaattcctt 204661 atggacagac gaaatcctat tccgacattg caaatgatat aaataaacca gcagctgttc 204721 gtgctgtagg tgcggctatt ggggctaatc cggtattaat tactgtaccg tgccatcgtg 204781 taataggaaa gaatggctca ttaactggct atcggggcgg atttgaaatg aagacactgc 204841 tcctcgatct ggaaaagcga gcttcatctg aaatggatgt tcctcattga aagtgaatca 204901 tctataatgg gttggattct tttagaggaa agtaaagacc agtttactga taaacttgac 204961 aacttttaaa atttagcata tcttatacgt aacttaataa tcgatgcaga tgtttatttt 205021 tccttttaaa atatgtaggc ctttagcatt cttttcatat ttcattttaa atattgatag 205081 gatgaaaaag tatcctaata aaaaaggaag agaacatgag tcgatttatt tgataatcag 205141 gactatatta aaggaaatga aaacatagca taaagtaaag accaataata aggtagctct 205201 tcaaaaaact tcgctgaagt tagttgaagt gaagccgaca attttcagga ttcaatgatc 205261 taacataatc attgaaattt tgaagttgtc ggcttttttg ttggaaaaaa atagagataa 205321 ataaaaattg aaataaataa tagacaaata tgatctgatt gaaaggtctt ttgaccaata 205381 atgagtttta aaaaagggag aatttagaat gttagtttcg ctgagtttgt catcattatt 205441 aacattattt tttattatgc ttatggcttc tgggattagt ggactattgt ttttacatcc 205501 gcgtgtaccc ttgagttttg ttcgcattca tattgggatc ttggctttac cacttttggt 205561 ttccttactg attcttgcca atagtggtgt gagtggaaat gttggccctt ggcacttaga 205621 ttccttagct tgtttaatga ctttctttgt tcttgcaatt ggattcatca ttcagcgttt 205681 ttctgtacgt tacttaatgg gggatcgatc ttatcgaaaa tattttacgc tttttacttt 205741 cacaacagga gctgcttcaa tgacatggtt aagtggtgat ctccgcttga tggttctatt 205801 ttggggagca actcttgttg gtttaacctt acttataagg ttaaacagtg cttggcaagt 205861 ggctagtgaa gcagccaaaa tttctggacg gttatttttg ttaagttggt tttctttgtt 205921 ttttgcgatg atgtggcttt ttcatgccac aggtcaatgg cagctatcat tggttgtaac 205981 aaatgaaagt ttagctgggc tgggagaatg ggagagaaca gggattcagc tattgattgt 206041 actggcggtg atcattcctg cagctcaatg gccgttccaa agatggttgg ttgagtctat 206101 tgttgctccc accccagttt ctgcaattat gcatgcaggt ttagtaaatg ctggaggaat 206161 aatactaact cgattttcac ctctatttca tggtggtatc gcttcgatta tcttacttct 206221 gcttgctagc atttctgtat tgattggaac tggaattagt ttagttcagg ttgattataa 206281 acgccagtta gtaggctcca cgattggaca aatggggttt atgctcattc agtgtgcatt 206341 aggcgcctat atagcagcca ttattcacct tattttacat ggtttattca aggctacgtt 206401 gtttctacag gctggttcag cagtagggcg tcatgaagta tcgactcgca ctaatgaaag 206461 aacatcctat ttatgggtca tggctggtcg gattttatcc ttagttatag gtgttgcttt 206521 ttggctcact gctcctggag acgggtatca cttaatcagt gcgctgatct tagggtggtc 206581 attgtccgtt tcttgggatc agcttgtcgc ttttggagag ggccgaattg gccggattgc 206641 cggtttaact gttttaggag gagcagccct cgtatatttt atcattcatc accttttcta 206701 taagtggctg catacaacca tttttcaaag tgttcaacct ccaatgtcag ctgtcatgat 206761 tgtcgtatgt ctcttactct ttggcagtgc tttaggtacg tgggttgctc gtcatcgttc 206821 ttccgttttt ttcgcggtac tctatctttg gttagtccga ttaggtgaag caaaaccaaa 206881 gtcagtagag agtcacccag actaccttaa acaatatatt tcataaggag ctaatctgag 206941 atgggcatta catccgtatt aacgaaagat aatgtaaaaa agatagatac agatattgat 207001 gttcaagaaa gggatcttaa cgttttcatt acatctgcca gccgagtgat tgcgccactt 207061 tggcctattt ctacatttgc tgcacgtaat ccgtggatgg gacttgaaaa ccaacctttt 207121 gatcaggttg caagttggtt gaaaaacact cgcgatgttg atatataccc tagtgcgtct 207181 atgatccgtt cagcaaagaa taaaggtgag attgatgaag attttgtgga aatggggctg 207241 cagcgttggc ttgattcaca ttcctatcac atcccacggg acgtagcaga gcgattttgt 207301 catgctgcat taaagttaga tcccctgcct tccgaccttt tatcatcaca tgagctggag 207361 aaattagtaa gtgaatgtag tggattggat catatcgaga atgtgtttat gcagccacta 207421 agttcgtata tagagaatca agatggtgaa aggctagtca atatactaga tcatcatgtc 207481 attaaatgga gtaaattata tcttgatgac tctcaagcgg gttggacaat gcctaatcgt 207541 gaggaaggtt tctatcgtgc ttggcagcat cttattcaat atgatccagc acttagcaaa 207601 aagcagcgag aaagggtaaa aggttggccg aaagaggcac atttggcttt acaagaagct 207661 ttattcgcac tagaaatccc agagtcagaa atccagactt atcttgaagg tcatttactt 207721 tcattacctg gatgggcagg gatgatgctt tggcgctccc aacaatcgag ccacgaacat 207781 gcactactaa cagaatattt agcggttcga atatccatgg agtgggctct tataaagcca 207841 tacttacctt tgactaatga acgatctaag aaaacaattt caattgctcc ccttatagca 207901 gcttggattc attggggtgg gcttacatta gaagaatggt cacagatgac ggccagtgaa 207961 caaaacgaat atttatcatt tgcctacagc tttgatgaga aacttcgcaa gaaactttgg 208021 ttagaagctt gggaacaaac gtacactgat cgattaagcc agaagatcat ctcgaaacaa 208081 cgtgaaaccg gccgtgaaaa atctgcatta gctcaattag cattctgcat cgatgtacga 208141 tcagaacctt ttcgtcgtca actagaaaaa gaaggcccgt ttgaaacgat tggtattgct 208201 ggtttcttcg gggtgccgat tgcaacttgt gaacttggca gtaaacacag tcatgcttcc 208261 ttgccgatca tacaaaaacc gcaaaataaa ataaaagagt tcgcagatga ggatgtattc 208321 aaaaaataca atcaacggaa gcaagcaatt cattctttaa gccatacctt taaaacgatg 208381 aagcagaatg cgctttcgag cttactactg cctgagctaa gtggaccttg gcttactctg 208441 caaatggcag cccgtagctt tgtgccaaga aaggcgggtc gtttcattcg taatctccgt 208501 gaggcttggt tacgcaaacc tgatacaaaa ctctcgcttc atcatgatgc tacagaggca 208561 gaaatacctg tgggttttac tgatgaagaa aaagtgaact atgctcgcca agcattaaaa 208621 atgatggggt taacagagaa catcgcacca ttggtcgtga tttgtgggca tggcagtcaa 208681 agtactaata atccttattc tgcagccctt gattgtggtg cctgtggtgg agcggccggt 208741 ggattcaatg caagagtttt agctgcttta tgtaatctat cagaggtacg agaagctctt 208801 ttagctgaag gaattaaaat tcctgaggat acagtttttg cagcagctga acataataca 208861 acagtagatg aattacattg gctttatgta ccagagcttt ccgaagctgc acaagaagca 208921 tttgaacaaa ttgaagccgt tatgccgaaa gtgagacatc atgtaaacgc agaacgtcta 208981 gcccaattac cgaatttcca atcgaagcta aaaaatccga aggctgaggc aaaccgattt 209041 gcggaagatt ggagtgagat acgtccggaa tggggactgg ctcgtaatgc cgcttttatt 209101 atcggtaaac gtgaattaac tcaggattgt gatttggaag gcagagcctt tctccataat 209161 tatgattgga agcaggatga aagcggtgaa ctcctagcaa atattattgt aggacctgga 209221 actgtagccc aatggattaa tttacaatat tacgcatcaa cggtagcacc tcattattat 209281 ggcagcggaa ataaagcaac tcaaaccgtt actgcaggtc tcggcgttat gcaggggaat 209341 gcaagcgatt tgttagccgg actgccttgg caatccgtca tggaatcaga tcacgaggcc 209401 tatcattctc ctcttcgttt attgatactc atccaagcac ctagagaata tgtagaacgg 209461 ttattaaatc atgattcagc atttctgcaa aaagttcaaa atggatgggt ccgactggct 209521 agtcttgatc cagaaggatg ttgggaaagc tggtaatgat gaatctaagc atttatcaaa 209581 tggatttgtt actcaataca aaaatgataa acataaggaa gaggtgtgct gtatgaatgt 209641 aaaccaaaat aaaaaagtat tatttttgac ggatattgaa aacggtttgg agcctatttt 209701 acaagaagcg actaacactt ctgcagagaa tatgttgact atacaaagct atggtgccag 209761 tatttcacat ccttatggag aaatcatgag gtctgttatt tttgcgattt accaggaaga 209821 tgttgaggag atttttgtag taggaacaaa agataagaag acttctgcag gtaatggact 209881 aactcaactt gaaacaatga aagataaaat acaaacattg gattatctgt ttcaaaattg 209941 caagcctgaa tttttaggtg gtacggtcga tgaatggcta aatgaaaata gcagtgacac 210001 cattgaaaaa agtgttgata tgattcgaca tcatccccta gtgccgtcat atgttaaagt 210061 tagaggttta ttcgttaatc ataagggtgg aaaaccctca atcgcggagg ttcctgatgt 210121 taaaacaggt caagccatgc ctgatcattg cttgtcatga tgaaatgcag gtttaacttc 210181 taaacgcacc catatatgga gaaagcagtt ctaaggagat tgtatgagcg ctaatttaac 210241 tgattttgtc acgaaaacaa tagaggaaat gaactcgttt gatcgtgaaa atatggaatg 210301 tataaaaaaa ctaattagaa aagcaattga tttttatcat ctaaagtctt atgaagaagt 210361 tgaggaaacc cattcaggaa atgttcgatt tttgcatgtc cactctatga tggaagaaaa 210421 tatgttatcc aaaatgatag tggtcacaag aaacggtaaa actgatttgg atattgaagg 210481 tgtatatgaa ggatatgttg taagagaata ttaatgagac gaaatcacaa atagaatatg 210541 ccaatttttt tgctcaggag atgtattaga tatgaaaaag tctaagggtt ctattgaatc 210601 agagatcagt aagtccatta ctcaatggga gaaggattat cttgggcggg ggtctgtatc 210661 tgttaagact gatatactgc gggacatgat catcgtcaat ttaaaaggga ttttaacacc 210721 agccgaatat gtagtttgtg gatcaaaaga gggtatgtta tctatcaaac aaactcgttc 210781 agagttagtc gaatcaggta tagaaggcct taaggatatt atcttaaaaa taaccggaga 210841 aaaagtgaaa agttttcata ctgatttaag ctcccggaca ggtgaacgag tgatggtatt 210901 taaattatgt aatgatctag agaaaaattt ggaaaagatc ttataatcta aagaaaataa 210961 atgttttgac ggtgtggaat ttgttgtgaa ttgaacataa agaactgccg attcttttgt 211021 tttacaatta tggtatcatt gataactttt attcatatcc taagcggaca taaagagatg 211081 tcaattcata gtacactgtc atgttattcc tgtcgaaaga tctaacatcc gctgttgtta 211141 tgagcggatg tttttttaca tctattttaa atacatgaat ttgatgctgg tgattagtca 211201 cttgaacaat atttgaaaac atccttgtca cctgccgggt ttccccaagt gtttagtgac 211261 atgattatga gaccaacttc gtaaagcttg ctgataaatt taagcggtga acaaaattga 211321 tatgctgtct tcagtttcat ttcacggaat tagtcagaga taaaccttta attaaatata 211381 tccaaaaaac ggattgacat atcgaaatat aacgatataa taatcgatat ggaaccaatt 211441 gaagtattca aagccttatc aaatgaatca aggctgcaaa ttttacaatg gctgaaggag 211501 cccgatcgtc attttgcacc ccatgaaggg attgatatga acacaatcgg ggtatgtgtc 211561 agtcaaataa cagacaaatt gaaaatgacg caatcgacag cttctcaata tcttaccatc 211621 cttttaagag ccggcctaat taaggcggag cgaatcggaa agtacacgta ttataaaaga 211681 gatgaagaag ccattgggaa acttgctgac tttcttaaaa cagagatata aaaataaaca 211741 tcaaaagatg tttattttta caccatacat atcgacatat tacgatgtgt ttattttttt 211801 ataataacat atcgataatt cgtgatatgt ttattaataa ttaaggagtg aatgttttat 211861 gtctaacact tggaaaattt atattttagc cattgtcagc tttttagttg gaacctcaga 211921 gtacatcatt tccggaattt tggatcaaat tgctcatact ctcgggatca ctttagctgc 211981 cgcgggccag cttattacca ttttctcact tgtatatgct ctttctacac ccgtacttat 212041 ggcgttgaca gcaagtatgg atagacgcaa attgatgatg tatgccctag gtttgtttgt 212101 gttcggtaat gtcctggctt ttgtactgcc tggttatgga tggtttattg cagcgcggat 212161 cattatggcg atgggagcag gtgtggttgt tgtcaccgca ttaacgattg ccgctaagat 212221 tgcatcggaa gggaagcagg gcagtgccat cgctacggtc gtgatgggat ttaccgcttc 212281 tttaatcatt ggtgttccgc ttggaagaat gatagcagta gcattaggct ggaagtctgt 212341 atttggagcc attgctttgt tgggattgat cgcaatggtc gttattttct ttactcttcc 212401 gtatactgaa ggggataagc ctgtgccttt gcttcaacag cttgctcttt tcaaaaaacg 212461 gaaagtggct atgggattat caatcacttt cttctggctc gggggatatt ctgttgctta 212521 cacttatttg tcaccgtatc tcttgaacat ctcaggtata aatggcaagc tgctcagcgg 212581 tgttttgctt atatttggaa ttgccagttt ggttggatcg aagtttgggg gatatagcac 212641 cgataaatgg ggagtgccct ttacactcgt tggcgggatg acgttgcata tcgtcacact 212701 gattctgctg tcacttgtta ctcattccta tatcggagtg ttggtgattc tcatattatg 212761 gtcgtttgcc gcatggtcca ccggtccgac acagcaattt cacctggcta caatagaacc 212821 ggaaatgtca ggtgttttgc ttagcatgaa tcagtcaatg atgcaattcg ccatggcggt 212881 cggcgcaggt ataggagggg tttttgtgga aaacgtatca ttggcctcga ttacctgggt 212941 tggtgcgtta ggggttatga ttgcaattat tgcatcattg ctgattttca attcgcaacc 213001 gaaacaagcg ctaaaagata tcaatcaata atttcgaaag ttctaacatc cgctcgttat 213061 acaagcgggt gtttttttta gcgtagtcag tccatgcatg agtcttccaa gggccgacat 213121 cgttctgtat gtgtcgaagg tgcactgaag ctgaatgaga tttcttaagg ctttgccgcg 213181 gcgagctgaa gtacagtacg attgccttga tcgaacactg gaaacacaag agaacgtaaa 213241 cctgaacatc cgcgtaaacg tcaaggaagt tgccacttgg ggagtaaaca cttgcatcat 213301 ctcgctgaaa ggcctagaca atgcggatga cagattcgta ttgccggaag taaacacagc 213361 gcttgctctg tttccgttgt cgattgcagc tgattgctta ctaatgctgc cctgcatctc 213421 ggttgtgatg tcgataagca gcgtaatgaa gagtgttact gtggagtaag atgtttaacc 213481 cctctggata ttttagccga aggggttttt agtatagata tttgatttaa attacaggag 213541 acttcattca tttaaccaaa gtcattgctt tcttaatcac taaagtttat ttgaaaataa 213601 tctcttgatt taatttcctc gaagagattt tttgtcaatc tattaggcat cagaattttt 213661 ataacataat ggaccgtctt tttgacgttt tgtttataga acaagaaaat attcaaaaca 213721 taagtggaaa attaggggtg agctcctgtt tttctcgaga ggatagcttg tcagcttttc 213781 tatttttaaa gggttaaaat attctattta tactaattaa tgtaattttt aggataatat 213841 acaaaatccc ccttacttcg acaattgcaa tctggtatta tcgtatcgca tgggagctat 213901 gtcaatagac tctatgcaaa aattgagagg aggtttactt atgaaaagaa accaaaaaga 213961 atgggaatct gtgagtaaaa aaggacttat gaagccggga ggtacttcga ttgtgaaagc 214021 tgctggctgc atgggctgtt gggcctcgaa gagtattgct atgacacgtg tttgtgcact 214081 tccgcatcct gctatgagag ctatttaaca tttgagaata gggagttgag cgtatttgct 214141 tatactcctt attttctctt aagggggatt ttatatgtca tatgatcgtg ttaaagattt 214201 tgatttgcca gagttagcgg ttcatttaca gcctcatggt gctgtaatga ttgatagaaa 214261 aagtatgttt tatttcagac tcagtggacg tggagcacag ttggcgtttc tgttatcaaa 214321 aaacaaaaat cttcataaaa cggcacgtat ttgggagatt atgaaaaaag aagagatgag 214381 tgctgaccaa ttaaaagaag agcttagtgc ccatccattt acggaggctt ggacggaagg 214441 gctgttagat cagcctttac acgtttcggg ttcgctagat tcatatttac ctattagttg 214501 taccttacag ttgacaaatg cttgtaattt aagctgttcg ttttgctatg ccagctcagg 214561 taaaccatat cctgaggaat tatctagtga acaatggata ttggttatgc aaaagctagc 214621 agcccatgga gttgctgata ttacgctgac cgggggtgaa gcaaagctga tcaaagggtt 214681 taaagaatta gtcgttgttg caagttcgtt gtttaccaat gtgaatgtat ttagtaatgg 214741 attgaactgg cgagatgaag aagttgaatt acttagtcac ttaggcaatg tttctgtaca 214801 gattagtatt gatggtatgg ataatacaca tgaccaatta agaggcagaa aaggcggctt 214861 taaagaaagt atgaatacca ttaaaaaatt atcagaagca aacattccag tgattgtcgc 214921 tatgaccatt aatgagtcca atgctgatga agtatcagat gtggtggagc aatgtgccaa 214981 tgcgggtgct tttatctttc gtgcaggaaa aacgttatct gttggacgtg cgacagaagg 215041 ctttaaggct ttggatattg attttgaaga aatggttcaa atacagctta gggaagcacg 215101 tcataaatgg ggagatcgcc tgaacataat tgattgggag cacgaagaga gttcgttcac 215161 aacagatttt tgtacaccag gatatcttgc ttggtatata agagcagatg gatacgtaac 215221 tccttgccaa ttagaagatt tgccgctagg gcatatttta gaagatagca tggctgacat 215281 tggttcacct gctcgtttgc ttcagttaaa atgtgaagca aaaaattgca aatgtatagg 215341 gaaaattgag ctatctgaac cggacttacc ttttcaaaaa gaagtcaagg cagggattca 215401 ggaatgaata gtctatcatt ggtgttctgg agtattttag cagttgttgg attactgtta 215461 tttattaaat tcaaaccccc aacaattgct tcactactct taagcaaaga tgaggcaaaa 215521 gaaataagca ttcaatttat aaaagagttt gttgggatag atgtagagaa ctgggatttt 215581 tattcagtat attggtatga ccacgataca gtaaataaac ttcatcactt aggcatactt 215641 aagaaaaata gaaaggtttt atatgatgtt gggttggtcg aatcatggag agtccgtttc 215701 gttcaccaga atcaatcatt tgtagttggt gtcaatgcca atcgagaaat cacttttttt 215761 tatgcggatg ttccgaaaaa aaccctttcg gggaagtttg aacaagtttc tccagagaca 215821 ctcaagcaga ggttaatggc ttcacctgat ggactttggt ctagagcaaa tatgactggt 215881 actggtaaaa aagaggagga ttttcgcgag gtcagtactt attggtacat agcggaagcg 215941 ggagatattc ggctcaaagt gactgttgaa ttacagggcg gccgaatttc ttatattggt 216001 actgaacaag aaatactaac agatcaaatg agtaaagtca ttcgagatga acaagtggaa 216061 tcgacattcg gagtatctgg tatgctgggt tcagctttag cgatgatcct tgcgattctc 216121 atccttgtat ttatggatgt gcaaacaagc ataatcttca gtcttgttct gggtttgttg 216181 attataatat gccagtcatt gacgctgaaa gaagatattc aattaacaat tgtaaatgct 216241 tatgatgcaa gaatgagtgt caaaacggtc agtttattag gtattttgtc tacacttctt 216301 acaggattat taacaggatt tgtagtattt atatgttcat tggcaggaaa tgcgcttgct 216361 ggtgattttg gatggaaaac gtttgaacaa ccaatagttc agattttcta tggaatagga 216421 gcagggctca ttagtttagg agtgacttct ctgctgttta acttattgga gaaaaagcaa 216481 tatttacgaa tttcacctga gctttctaac cgaactgtct ttctatcagg ttttaccttt 216541 aggcaaggat tgaatatgag catacaaagt tcaattggag aagaggtcat ctatcggcta 216601 ttaatgattc cagtcatttg gtggatgagt ggaaatatcc tcatctccat tattgtatct 216661 tcctttttat gggcggtgat gcaccaagta actggatatg acccaaggtg gatacgttgg 216721 ctgcatctat ttatattcgg ttgctttctg ggagttctct tcatcaaatt tggttttatt 216781 tgtgtattag tagctcattt cattcataat ttagtactcg tctgtatgcc gctgtggcag 216841 ttcaagcttc agaaacatat gcatcatgat cagccaaagc atacttcact ctaatgatta 216901 ggagaagatt tgatgcaatt gatgcaagta caaaatttaa gcaaatgcta tcgaaatggt 216961 gatggggttg aacatttgtc tttctcaatt caacgaggag aaatcgtggc gctattgggg 217021 ccaaatggag ctggaaaaac aacgacaatt cgatgtttga caggtctcta taagccggat 217081 aaaggagata tcctcattga gggttctcct ccaggagata taaatgttca aaaaaaagtc 217141 gcgcttattc ctgatcagcc atatttgtat cccgctttaa ctgctgctga acatattcag 217201 tttagggcaa gaggatatca tccaggtaaa aaagatgtaa aagaaagggt ttatcatgca 217261 ttgaaggaag tgcacttgga ggagaaagca aaccaattgt gtggtcagct gtcaagaggc 217321 caaaagcagc gggttgtcct ggcgggggcg attgttcaag acgctttgct gtatatatta 217381 gacgaaccga ctgtgggcct tgatatccca tcaaaacagt ggctctctaa ctggttaaaa 217441 actaaaaccg atcaagggtg ttcagcattt gtatcaactc atagtctaga gtttgttata 217501 gagacagcag acagggtgat attaattaga gacggcaaac tcatgcagga tttgtatgtt 217561 cctcaattcg aagaacaagc ggaatggaga aaagaagtga ttcgtcttct aggggaatgg 217621 tcagatgaat aatatcattt cttttttatg gcttcagtca aaaaggcgtt ttgtaagtca 217681 aggtcaggaa aaaaaaatgc cttttttgat catgctcctt tttgttgggg ccatcggatt 217741 tcaagtaagt tttgtttcta gatctacgac atgggatatg agtattgctg gttgggtact 217801 tacaggtgtt tttatccttt atacggcatt tggacttttt tcaaatcgat taccaagtca 217861 aatggcagat attatatggc tttatggcac tgccacatct ttttcaaaag ttgtgtatag 217921 tgttttattt ttcagcgtca cttggaaggc gttgctttgg atcatctcag ccatattcgg 217981 tgatgtatta attgtgcttc tgtctggtga tcatatcaat ttattaggcc gatccataat 218041 ttttgtaggg ctctttttta tcgctgaagt gtggttgatg tcggtctctt gtgccagaac 218101 agtgaagaaa atgaaaaggg tatacgtttt agtctttctt ctaatgttag gcatttactc 218161 catatgtctt tatcgcttct tctttctcca acattcatct gggatatggg agagcattgc 218221 ccgttttatt agtggcgttg gattagtgtt tgatacattg tcaccgttgt atgtggttgt 218281 atttattggg attatcacag tctcttttat gacaattgct tttacgagcc gtcaggtaga 218341 aatgaaggaa tcgttggtga aagaagctga attctgggag gaatttcaag aacgtcaatt 218401 tggttcaggt caaattatac agaaaccaaa aacgacttgg tggggcttgc aaggtctaaa 218461 tggcatttgg tcttttctgt ggttggaact gttgcttttt aaaaaatatt tattttttca 218521 tagcattcat acggtcatgc tcagtggcgt cttttatgtc gtcattttca tgtatccaga 218581 atggttttat cttctattct ttcttatcgt ctcggcagtc atgttaagtt cctattattc 218641 aggaattgtc agacattctc aatcaggcac ccttcattta ttccccggtg ccctttggaa 218701 aaaaatcatt attctagagc tgacgaatac agtctggttg tatattcttt actgtgtttc 218761 tattactttt atggcagttg ggaatttagt ttattggtat atatatggct tagggatata 218821 tatatggttc atgacaataa ggctttttgc ttttacccat acaaaccgaa acgatattaa 218881 gctttcattg cctcaatact acaagtcatt ttttatggca ttaggcctga gcggcatttg 218941 tttgtatgtc attcatttat tgactgctga ctggtataca ttagtggtgg tcgtctgcat 219001 agggagccta agttggtgcc tgttttatcg tttcagatag tggttatgta gagttattgt 219061 tttaaaacga ggagaggggc tcttttatga attcaaatgg tgataaattg tcgttatctg 219121 ttcagaattt agcgaataca aatgagatca caattgttca agcgataggt gagctaaaga 219181 aatcgggaaa agatgcaata ccagttttgg ttgaggcctt aaaagaggaa ggctctttgt 219241 gtaatattgc tgcagctgtt ttaggtgagt ttggggaaga cgcgagtgaa gcagcggagg 219301 agctatcatg tttattaaaa agtcatgcgg aagatacaag aatggcagcg gcgatttcat 219361 taatgagaat cgggaagccc agtctgccct ttgtcatcaa aatcgctcaa gaaagtgaag 219421 ggcaatcgtg cttttgggca tcttggtgta ttgcatggat tgatccgtct tgcattgaac 219481 ctaagatgta taaatgtcta aaatacgagc atgaacatcc ttcaggaata gttgctccgt 219541 ttgcggctga agaggcatta ggaaagctga ttgcttttca gctgaaagat aaggaggact 219601 gaaaggatga aagatgaaca aatgttgact gaatggccaa gtcatttacc atggttgaat 219661 caatcacaga atgattttac atttccaagt gacacatatc ttcttcttta tttttggtca 219721 atgagctgtc caaactgtca ccaattaaca gacaaagtcc ttcaagatat aaaggatatg 219781 aatgtgaaag taatcggagt acatgtcccc tatatagaag aagagaaatc tatggaggtt 219841 gtcttgacgt atgctcttga taggggacta gctattccga ttgtattaga ccaaaactat 219901 gagatcgtca caacttgtca cgtacaaggc atccccagct tttgtctatt aagtcaatac 219961 ggtcagatca ttactaaaac gatgggagat gttggttggg ataagatgtt aaaaaagatt 220021 gcaggcttgt gaaattttcc gtcttgtatg tgcgacaaac ggttgaatat tatgatgaaa 220081 cggtccttcc tataagcagg aaggtttttt aatgaaatat ttttttatta gtaggtaaat 220141 tcatcaaatg ttctgctatg ctccaaatgt acacctttcc gtaagggcaa agtcaaatgt 220201 gaaaaaaaac tgttccaaag ttaatcagaa atttattttc atattgtatc cttcggtatc 220261 aagtgaaagg agcatcatat gaaaacatta tggaaagtcc tcaaaattgt ttttgtcagc 220321 ttggctgctt tggttttgct tgtatccgtc tcggtattta tttatcacca tttccagcta 220381 aataaggagg cggcactgct gaaaggtaaa ggcacagtag tcgatgttga cggtaaaaag 220441 atgaatgtgt atcaagaggg aagcgggaag gatacgtttg tgtttatgtc cggttcgggt 220501 attgctgcgc ctgcttatga aatgaagggg ctgtacagca agttttcaaa agaaaataag 220561 attgctgttg tagatcgggc aggttatgga tacagtgaag tgtctcacga tgacagagat 220621 attgatacgg tattggaaca gacgaggaaa gcgcttatga aaagcggaaa taagcctcct 220681 tatattttaa tgcctcattc gatatccggg attgaagcga tgtattgggc acagaaatat 220741 cctaaggaaa tcaaggccat tattgcgatg gatattggat tgccccagca gtacgtcacg 220801 tataaattga gcggagttga ccgattgaaa gtgagagggt tccacctgtt aacctcgatt 220861 ggttttcatc ggtttatacc ttccgctgta tataatcctg aggtgattcg acagtcgttt 220921 ttaactgatg aagaaaaaga aatctataaa gccattaact ttaagcaatt ttttaatgca 220981 gatatggagc atgagctttt acagtcttac caaaacggca gcaaatctgt gaatctgcct 221041 gcgccaaagg aaactcccgt cttgatttta gatgcagtct ctgaccaaaa tagacattca 221101 aagtatgcta tacaaaaccg aaaagactat gaagcgtttg cggctcaatt caatactgcc 221161 gatataaagg aactgagggg aacacacagt atttatttat atcagcctga tcaaatatat 221221 aaactgtcca tggagtttat gagaaaggtt cgctaggatg aagggttatc gtattttaat 221281 cgttgaggac gatgtgatga ttggtgattt gctgcaaaag attttgcagc gcgagggata 221341 tcgtgtgata tggaaaacag atggagcgga tgtgctttcg gtgattcaga aggtggattt 221401 ggtcattatg gatgtgatgc tgccgggtga agacgggtat caaatgtctg caaaaatcaa 221461 aaagctgggg ctgggcattc cggttatttt tctctcagcc cgcaatgaca tggacagcaa 221521 gcttcaaggt ttgcagatcg gcgaggatta tatggtaaag ccctttgatc cgagagagct 221581 gctattaaga atgcggaata tgcttgagca tcattatggg acctttacgc aaatcaaaca 221641 tttgtatatt gatgcggtaa cgaaaaaagt gttcaatgaa agcctgcatg atgaggtatt 221701 atttactgcg attgagcgga aaattttctt ttatttatat gaaaatagag acagtatcct 221761 gacaaaggaa catttctttg aatatctatg gcagctcgaa gatagaaacc cgaatattgt 221821 caatgtgcat attaaaaaaa ttagagctaa aatcaatgat caagcgggtg agatgattga 221881 aaatatatat ggagaagggt atcggctgaa taccgttgtg aagaaatgaa gctcaagaca 221941 aaatatcagt tgttattgtt tacggccgtc attagtgttc cgatgctatt gctggcggtc 222001 agtgttttga tgtcggtgat ttatgacagc atgtttaaac cgatgaatca tggtatgccc 222061 tttcacaggt cgtttgcata cccggcaatg atcgttgtat ttttgatatc actcttattg 222121 ttagcttttt tattttcaaa gtcgattcat tctctgttgc ataaaatcaa tctattaaat 222181 caaaccattc ggcatttggc gagtgatcaa agggtgcccg ataaaattga agtgaagcgt 222241 gctgatgaaa tcggggaact gatcaagtcg gtcaatttgt taattgaacg gacgacatat 222301 cgtgaactgg agctgagaca gcaggaggaa atcaaaaagg agcttttgca aaaactgcgg 222361 catgacatta atacaccttt aacggctctc aggctgcagt tattttattt ggaagaccaa 222421 tgtcatggtc aggctgtatt cgaatcattg tatcagcaaa tcgaatatat ctcggaatta 222481 actaatgaat tcaatctata ttccgctgag acgctggaaa gctcttatat tgtaaatgaa 222541 gaagtgcgtc taaacgagct attagaaaca gcggtgaaaa agtgggatta tttatacagt 222601 atgagtggga ttgagctgca ctataagccg gcagatcaag atgtgatatg gatgagcaac 222661 acgttatgga tggaaaggct gtttgataat atttttcaaa atacgttaag gcattcaaaa 222721 gctaaaaaga tggaagtcac gattgaacat ggcgatgttt ttattcgtga tgacggtatt 222781 ggatttgatc ggaatgagag cagtgaggga cttgggttaa agattattga ggatacatgc 222841 aggctgcttg cgattactta tgagctgcat acaaatgata acggaacggg gttcttgttt 222901 tcaaaagagt gaccccgctg atgtttttct ttctcctata aaatttatat aatagggaga 222961 aagaaatggg gtgaacatca tatgtttaaa aaaatcatca aaacgattaa gtacctctca 223021 agcagttcta gtgaccgata tcgcagacac cggcattaca gcagcagccg gcgcagacat 223081 tatcgcagct acagcagcag ttcgggcaaa agaagacact acgaccgtta tggcggcagt 223141 catcgttaca aacgccggag ctacagcagc agttaatcca aaaaaagttc ttgttccgct 223201 tttgggacaa gggttttttt atgtgaccga ttgaatggcc cggtttagat cctcgcgaat 223261 ggaagcggtg tgctgatact cttcctcaat gcccaataat cttttcagca gcaaggttac 223321 ttcctttgtc agtgttaatt cctccagcca agtgccgttt ttcttctttt ttcctttata 223381 ttgagagtac agcaagaata acagcgtttc tccgagatcg aagaagtcat cctgttttcg 223441 tacctttatt tcctccattt cttcaggagt caattgtttg gcaaggccga aatcgatgag 223501 gcagagcctg ccatcattga tgatgatatt aggcgttctg atgtcgctgt ggaagataag 223561 gcgatcatgc aggtattcta taatctcaag cagctgcgaa atcagttgta acgccataag 223621 ctctgtgaac ggctgttttc gaaaaaataa taattcttct atattctctc cctcaatgaa 223681 ctgcatgaca taataagcct gtccgtctat gatgaattca tctatgaagc ccggaatttg 223741 cgggtggtga atgtttttga gcagttttat ttcctgctgg aatcggactt tctctttttc 223801 ctttttggct tttgtcggcc gaagctgttt taagacataa ggtgtttgag ctaggatatc 223861 ggtgcacaaa taaaccaaac cgtagcctcc cataccgagg cactcttcga ttttgtattg 223921 atgatttaag ataacgccgt tctttagagg gcggtcaaat agcagttttt ttagaagttt 223981 taatgccatg tctgcacttc ccttggttgt actgactata gtttaccttc tagacggaga 224041 ataaaaaaga gccggataac cggctcggta taagttaaaa ctgctttgtc acgtcgtatt 224101 cataatctat ttttgctttt acgttgctca tcgtcgatct ggctgtcgct aatgtattat 224161 atttaaaact ccataccttt gccacactga gttgatccga caaagagata tcataagacc 224221 ctgaagtcga gctgtttaca agggcacggc tccattcgtt attttcgctt gtcatgatca 224281 gatggcgtgt atttccctgg cttggtgttt gagtggcggt tgtttgaact ctggttacaa 224341 tggcatcacg cggtatccca gattggtttg ttaaatcaac cttgatcacg ctggagtcag 224401 aacctgaggg gctaaggctt gtatttcctt tattttcagc aacgccgctg aattggaacg 224461 ttccgctgcc tgatttgatt cggtcttcaa ttgaaagcgt aaagtacatg tttccagtat 224521 aggtgcctcg tgacactttc acatagaagg tatccgtcgt gttttgggcg tctgcatttg 224581 cataaataaa agaagaaaac gtattagggt taataacttc tgtcccttga gaaacaggta 224641 ttctgttctt gtcataaatt tcaattttca tccctgtata cgcgctctgg tatgtactcc 224701 tcatgtatac tttttctccc ttattagccg taaaagtgaa ataggcttca tcttgaccag 224761 cttccagtat tgttgtatcg atatttttat atttccaata accgatcggc attgcggtat 224821 caaatgaatt gtttcctgtg atagcagtga ctccgacagc tgatgccgaa tacgtaaagg 224881 tagataagac agaaagcata acagcgaatt gaataagcca ttttttcacc atgcaaacaa 224941 cctcctttta tttccatcat acataataac gatttaggtg taaataaatg ttttttgagg 225001 ttaatatata cattatattc gccgataaaa aagaataaga gagaatactc gggagggaat 225061 tcaatgcgtc tgaatcggca atttatccgc actcagctga ttgcacagaa catattgagc 225121 aagaatgcgc ctgccaaacg ggagaatgcg actgaaaatc cagcggcagt tctggaaaag 225181 gcatatagca ggcttaagtc acaatcttca actgggggaa tcaatcagtt caattattct 225241 aaaaccagcg tgtcgggaaa cagcgggacg ttcagcaaag tgtatcaatc agcgaatgat 225301 cgaacagtga cagacacagg ggaagaaaca gtgattcaat cccaaaaccc ctatgaatct 225361 gagagtgata tcagaatcaa aatactagat gaaaaataca gcaggatgaa tgcgattaat 225421 aaaacaaagt ctgatccatt aggctatatt aaggataagt accaaaattc aaagtctcct 225481 tatttcagaa gtgatctgtc agctgcagaa agacaggccg cttacgataa tgaaacagaa 225541 tggttattca aagggaaggc gcaaaactat aaccttcagg atgctgtgtt tcggaatgtc 225601 acatttcatg gggaagtgga agctgagaat gaaaaggtgt atcagcgggg acaggttaac 225661 cagcagctgc aagtactgtt gaatcgaaac catattcata ttccagaggg gacagagctg 225721 acgtttacaa tcacaccgat tgactatcag gtgcgggtaa gcgggacaga cgatcaggat 225781 ctgatcaagc aaattgagca agtgctgcaa tctggagaca acagcaaaga actattttta 225841 cacatcatga aaagtcaaag cagtgattca gcacaatttt ccgaagaggc ctataaaaag 225901 tatcaggcag ctcgtgagat gtatgaagtt acaggctacc atttgaagga tttagaagtg 225961 attgatgggc ggtacgtcac gcctgaggga cgtgacttaa tggatgtata taaggaagag 226021 cttgaaaaag atccagtgca gaaacaaacg gcttcttatg ctatatctta ctatcgttca 226081 gagctcagta aaatcgcgga agccgggtat aatgccattc cggatttcat cctatcaatt 226141 gattacagca atggatctct gagagatgtg ggacaaagca agagctatgg gaccggagat 226201 accgggtggc ttgaagcatt aaagcgtcaa acgggtgtga attattaggt aagctgttca 226261 tgtaggacag cttatttttt atgagaatct aaggggtgaa ttaatcccaa tattcaaata 226321 attttattat ttttatataa aagattttaa aagaagtgaa cgattcaaaa ctctgaacaa 226381 aggtgtttac ctgaaaaaaa caattgtatt ttccagagaa atttattatg atgaaataag 226441 taatttagga gattatataa caattttaag tttgaatttt ctgattgtta tcactgattc 226501 atgtgaaggc aagcaggtct gctgttttct catttatgag tattttgtta ggaggaggaa 226561 gaggagtggc aaataaagaa ttaaagaggg gcctgggcgc gcgccatatt cagatgatcg 226621 ccttgggcgg tacaatcggt gttggcttgt ttatgggttc tgccagcacg atttcatgga 226681 ctggcccatc tgtccttctg gcttatgcaa tatgcggaat ttttatcttt tttattatgc 226741 gtgcgatggg tgaaatgctg tatgtcgagc cgagcacagg ttcttttgcg acgttcggcc 226801 atcaatatat tcatccgatg gcaggttata taacagcatg gagcaactgg ttccagtgga 226861 ttatcgtcgg catgtcagaa attatcgctg tcggttctta tacgaagtat tggttcccgg 226921 atttgcctgc ttggatacct ggtatcgtgg caatggtgat tcttggtgcg gcgaatttaa 226981 tttctgttaa gtcgtttggg gaatttgagt tttggtttgc gatgattaaa atcgtgacga 227041 ttatcttgat gattattgcg ggaatcggaa ttattttctt cggttttggc aatggcggag 227101 atgcgatcgg tttgtcgaac ctgtggtctc acgggggctt ctttgcagga ggtttctcag 227161 gtttcttctt tgcactgtct cttgtcattg cagcctatca aggagttgag ctgatcggga 227221 ttacagcggg tgaagcgaag gacccgcaaa acacgctaag aaatgcgatt caaagtatta 227281 tctggcgtat tttgattttc tacattggcg ctatttttgt gatcgtgacg gtgtatcctt 227341 gggatgagct caactcactc ggaagtccgt ttgtgtctac gttctcgaaa attggaatta 227401 cggcagcggc cggcattatt aactttgtcg tgattactgc ggcaatgtcc ggctgtaaca 227461 gcggtatttt cagcgcgggc cgcatgctgt atacactggg tgtcaatgga caagcaccga 227521 aattctttaa gaagatttca cgcaatggtg tgccgctgta tggcacaatt gcggtgctga 227581 tcggtttggc tgtcggcgtt gtactgaact atatcgcgcc gccgaagatc tttgtctatg 227641 tatacagcgc aagcgtgctc ccagggatga ttccttggtt tatcattttg atcagccata 227701 tcggattcag aaaagcgaag ggtgctgcat tagataaaca tccattcaaa atgccgtttg 227761 ctccttttac aaactatttg acgattgctt tcttgctgat ggttctggtt ggcatgtggt 227821 ttaacgatga tactcgtatc tccctgattg taggcgtgat tttcttagcg cttgtggtca 227881 ttagttatta tgtgtttggg attggcaaac gcacgcaggc caatttgaca aaaagcgaac 227941 aagcagctga ataacgataa aaaagagaca ttcacggatg tctctttttt tatttttcgc 228001 gtatggattt tccctatttt agcaagctat agggtaaaga tagcagaagg aaaggtgttc 228061 ataaaatgga tgttacactc ggttatttgc gcgaatcact ttcgaatcat ctagaaaatg 228121 aagtctgcca gcgtatttgc aagaagatgc tggcgaagcg ttatgcaaat gaagaggaat 228181 ttgtaaaaga cttagatgat aatgaaatgt cttttttgaa ccatgtatta gaaaaagaaa 228241 ttaagtatgc ccagaatgaa caggatcaaa aacgggccaa ggaattaaac gaggtgtatg 228301 aattactgct ttgagaaagg cgggtaagaa atgggagcaa ttgaacgaag cggatataca 228361 tttcagccgg agtttagcgt tgtccgtcaa aacggagcca tccatgtgta ccatcaagga 228421 gaatttgtgg aagaaatcga atttgaattt aacggggaat atcccgatca tgatttgatt 228481 gaagagcttg tgaatcatta ttgttttgag catgagattt agagccctgc cgtgcagggc 228541 tcttttattt aggatgtaat caggccatac tttttcagga tatccacggt gatgtttttg 228601 gcttttgtgc cggaatcatc gacattggtg acaaagacat aagagccatg ctctgttttg 228661 atgaatccga caaaccatcc taatcccata tcagtcaggc gggttccggt tttcccgtag 228721 agcgtgtaat gatcgccttc ctcttgaatc atcatgcgct tgacgatttt catcaccggc 228781 ttgtcaaatg gaagctcctc tttagccagt ttctccaaaa aagtttcttg ttccagcgga 228841 gatattgtga gcgagctttg cagccaaaac tggtcgattc ccccgctgat atcctcgttg 228901 ccgtaagata gagtatgaag ccatgttttc attctttcct cgccgatatc tctcgctaat 228961 gcctgataat accagattgc ggattcgcgc atggccgagc caagcgtatg gtcgcggttc 229021 catgattcga attcacgctt gaccccgtcc catcgtttaa catcgtattc atctcttaca 229081 gctttgacct gcaaaccgat taaagcgttc acgactttaa aggtggattg cggagtttgt 229141 ctttgatttg cccgttttct gttatagaca aatgtctgat ccttttgtaa atcgtgaaga 229201 atgaaggttc catccgtatc cttgaattca tcatcgacat tcattttgct gacattcaag 229261 tgtttttcat gagcagatga tgctgcgtgg acggagaagc cgccgatccc tgcaatactc 229321 agcacaagca caacatatat ccattttttc attttgttct ccccttcgtt ttgattaact 229381 accttttctc tctttcgttt gttcttcctt taaaaaataa tcaaaaagcg cttaaatttg 229441 gttttgcaaa caaatactgt tactgggttt atagtcggaa gataacgtga aaatagaggg 229501 taaaaaggaa ggcagggtaa gcggatgaat gagcagattc cacatgacaa aagtctcgat 229561 aacagtctga cactgctgaa ggaagggtat ttatttatta aaaacagaac agagcgctac 229621 aattcagatc tgtttcaggc ccgtttgttg ggaaaaaact ttatttgcat gactggcgct 229681 gaggcggcga aggtgtttta tgatacggat cgattccagc ggcagaacgc tttgcctaag 229741 cgggtgcaga aatcgctgtt tggtgttaat gcgattcagg gaatggatgg cagcgcgcat 229801 atccatcgga agatgctttt tctgtcattg atgacaccgc cgcatcaaaa acgtttggct 229861 gagttgatga cagaggagtg gaaagcagca gtcacaagat gggagaaggc agatgaggtt 229921 gtgttatttg aagaagcaaa agaaatcctg tgccgggtag cgtgctattg ggcaggtgtt 229981 ccgttgaagg aaacggaagt caaagagaga gcggatgact tcattgacat ggtcgacgcg 230041 ttcggtgctg tgggaccgcg gcattggaaa ggaagaagag caaggccgcg tgcggaagag 230101 tggattgaag tcatgattga agatgctcgt gccggcttgc tgaaaacgac ttccggaaca 230161 gcgctgcatg aaatggcttt tcacacacaa gaagatggaa gccagctgga ttcccgcatg 230221 gcagccattg agctgattaa tgtactgcgg cctattgtcg ccatttctta ctttctggtg 230281 ttttcagctt tggcgcttca tgagcatccg aagtataagg aatggctgcg gtctggaaac 230341 agccgggaaa gagaaatgtt tgtgcaggag gtccgcagat attatccgtt cggcccgttt 230401 ttaggggcgc ttgtcaaaaa agattttgta tggaataact gtgagtttaa gaagggcaca 230461 tcggtgctgc ttgatttata tggaacgaac cacgaccctc gtctatggga tcatcccgat 230521 gaattccggc cggaacgatt tgcggagcgg gaagaaaatc tgtttgatat gattcctcaa 230581 ggcggggggc acgccgagaa aggccaccgc tgtccagggg aaggcattac aattgaagtc 230641 atgaaagcga gcctggattt cctcgtccat cagattgaat acgatgttcc ggaacaatca 230701 ctgcattaca gtctcgccag aatgccatca ttgcctgaaa gcggcttcgt aatgagcgga 230761 atcagacgaa aaagttaaat taaaaagctc tcttccttta tcgaagagag ctttttgatt 230821 acttcttttt ttcatcgtag tattggacgg gatacatgga gccttctgat accattttgt 230881 tgtcctcgat atcttgcggg tccgggtggc cggctttatc aactgggaac gtttccatgt 230941 ctggctgttt tgttattttc atcttcatgc tgtgaatgaa ttctcttgcc ttttggcgat 231001 ttgacgggtc ttttaataga taagaagtga tgccgacagt tgaaacagcg agacctgaaa 231061 gtaacagctt ttgtttcatg gtgatactcc tttctatttt aagaatagtg tttcctgtat 231121 cattcccgtt ttggaaattg ctaaacctgt tgtgttttta tcattggaat taacagtaaa 231181 ttccatttaa gaagaaacta gtgacttcat tcctgtattg gaaggtaata tacattgact 231241 tattatagat ttcagtcaaa attcgataaa tattgacaaa gtaaagtaat cagaataata 231301 atataattag caagagaatg tcatcataca tgaaaggtgt ttacgatatg aatcaattgc 231361 atcgaagaat gggaacgttt tccctcatga tggtcgggct cgggtcgatg atcggttcag 231421 gctggctgtt cggggcttgg cgtgcggctc aaatagcagg accagctgct attatttcat 231481 gggttattgg aatggtcgtc attttattta ttgctctttc ttatagtgaa ctaggttcta 231541 tgttccctga agcgggggga atggtcaaat acacgcaata ttcacacggt tcgtttatcg 231601 gttttattgc gggctgggcc aactggattg cgattgtgtc cgtcattccg gttgaagcgg 231661 tggcctccgt tcaatatatg agttcttggc cttgggaatg ggcgaaatgg acaagcggtt 231721 tggtgaagaa tggaacgctg actggggaag gactagcgtt tgcctctgta ttgcttctca 231781 tttattttct gctgaactac tggacagtca atctattttc gaaagcgaat tcattaatta 231841 cgatttttaa aattattatt ccgggtctta cgattggagc tttgctgttt gtcggattcc 231901 acggagaaaa ctttactggc ggtcaaagca ttgcgccgaa tggctgggca agtgtgctga 231961 cggcggttgc cacttccggt atcgtttttg cgtttaatgg tttccaaagc ccgattaata 232021 tggcgggtga agcaaaaaat ccggggaaat caatcccgat tgcggttgtt ggctctcttt 232081 ttgttgcgac agtgatttat gtcctgctgc agatcgcctt cattggagct gtgaatcctt 232141 ctgatattgc tcacggctgg agccatctga attttaattc tccttttgct gatctggcga 232201 ttgcgctgaa tattaactgg cttgttattg tgttatatgc agatgcattt gtatcaccgt 232261 ctggaacggg gattacgtat acggcgacaa cgtcccgaat gatttacgga atggaaaaaa 232321 acaaatacat gccgagtata ttcgggaagc ttcatccgat ttacggcgtt ccgcgacaag 232381 caatgttctt taacttgatt gtttcgttca tctttttgtt cctgttcaga ggatggggcg 232441 tattagcgga aattatttct gttgctacgt taatttctta tatcaccggc ccgatcacag 232501 tgatgacatt gagacggacg gggaaagacc tgtacaggcc tcttcgttta aaaggcttaa 232561 atgtgattgc tccgcttgga tttatctttg cgtcactggt gctgtattgg gcgcgctggc 232621 cgttaacagg acaggttctg tttattatcc tgatcggtct tccgatttat ttctattatc 232681 aggcgaaggc gaaatggaaa gggtttggcc ggaactttaa agccggcgtc tggatggtgt 232741 tttatctgct ggccatgatg gttatttctt atttgggcag tgataaattc ggcggcctga 232801 atgtcattca ttatggctgg gatatggttc tgattgcgat ggtatccctt gtattctatg 232861 tgtgggcgct gaagagcggc taccagacag aatacttaaa ggatgcgaaa gagataaatt 232921 ctcagctgct taatggacag tcagaagctg ctgccggaaa agaataaaat atagaagaaa 232981 accttgcgat agttgtcgca aggttttttg cttttaataa ccctttttta ctttgtggaa 233041 aagatcagga tagttggtga acactcctgt tacgccccaa tcaagcaggc gatgcatatc 233101 agcttcatta ttgactgtgt aaggatgaag caggaggccg tggctgcgga tcatacggac 233161 gttttcttga tttaaagctt tataatccgg gcccgcaccg acagcgtatg ttttgatttc 233221 ttccagggca gcatctgtca ttgacgccat ttgtttggct tccagcaatt gaacggtcgg 233281 caggtttggc tgtaattgat ggacttttac caggctttct ttgctgaacg attgaatgat 233341 cacctggcct ggcttagaat gctttcccag taatttatgt ttctgcaaag aagcgatcag 233401 tttttcttcc atacctgggt aggtgtcagg cgattttgtt tcaatgtagt agttcgcgtg 233461 ctttccgaaa cggtctaata cctcttctaa tgtaggaact ttaaggccga cgtactgcgg 233521 ctttgctttt tccggatagg cttcattaaa ccaagaaccg gcgtcaagct tcttaatgtc 233581 tgcgagcgta tggtctttca cccaacccat tccgtttgtg gtgcggtcca gtttttcgtc 233641 atgcatgaca atcaattttc cgtcttttgt catttgcaga tccaattcaa taaaatcagc 233701 tttcattttc tgagcggttt cgtaagacag aatcgtgtgc tcaggcacat atccagaagc 233761 ccctctgtgc gcgacggtca ggatacggtc aggtgacagc aggtttcctt ttgacgctgc 233821 cgacactggc gttaccataa atgagagtaa gcccagcgac agaacaaaca aggccagtat 233881 tctatttttt ctcatgattt ctcctcctta tagataagca ctacctgtct ttcataataa 233941 aaaacggatg taaacggcgt gttggaaaac tattaatctt ttatgtgtct ttcttaaaca 234001 tgctctgccc gttttcctgt attccacgtc aaagccaaga agacgatggc aagaatgcag 234061 gatgagatca gcatgataaa gccgccgttc cagttaaaac ggtccacgac aaagcccata 234121 atggcgtttg cgaaggcgga tccgccgatg tatccgaaaa atccggtcaa accggctgca 234181 gttccggctg cttttttcgg tgctaggtca attgcttgaa ggccgatcag cataacaggt 234241 ccgtagatta agaagccaat gctgatcagg gcgatattgt ccacgagcgg attgccggcc 234301 ggattcagcc agtacaccaa tacggcaatg aaaacacccg ccataaacaa aacgcctgcc 234361 ggtgcccggc ggcttttgaa gaatcggtca ctgatccagc cgcacaagat cgttcccggt 234421 atgcctgcgt attcgtaaag aaaatacgac cagcgtgagt cttcaggaga aaagcctttg 234481 gcttctgtta agtaagtagg cgcccagtca accacgccgt atcgcacgaa ataaacaaat 234541 acattggcaa aagcgatgta ccaaagaaat ttgttgttca gcacatattg aaaaagaatt 234601 tcttttgttg ttaattcttt ttcctgattt ttaaaagcgt gttttggata gtcattccga 234661 tactcttcaa ttggcgggag tccgcaggat tgaggcgtat cacgaaccaa taaaacaatt 234721 aaaaatgaaa tgataatggc gatgatggca gggaagaaaa acacgctttt ccaagtgacg 234781 aacatcgcga tcccaagagt gacaagcgga gcaagaatac cgccgcctat gttatgggcg 234841 acattccaga tcgacatttt tgtgccgcgt tcacttatgg agaaccaatg ggccatcgtc 234901 ctgccgcatg gcggccagcc cattccttga aaccatccgt tgataaacat aaaaataaac 234961 atgatggtga cgctcgaagt cacccaaggc attgaaacga atagaatatt aacgattgct 235021 gataaaaata ggcctgtcgc cagaaaatat ctcggattac agcggtcaga caccattccc 235081 atgatgaatt tgctgaagcc gtacgcaatg gacacagcgg ccagcaccaa acccagttct 235141 gttttcgaaa atccctgttc ctgcagataa ggaatggcaa aggcaaagtt tttccgcagc 235201 aggtagtagc ctgcgtagcc aatgaaaata ccaatgaata cttgcagtct gagccgtttg 235261 tatgccgcat ccatctttga atcatccagt ctctcaatat gaggagccgg tttaaatata 235321 ttaagcatta ataattatcc ccctttgctg tttgtgctgg atgtgtggcg tgcctccttt 235381 cccgaaaaac aaaaagagcc agaaaacacc ccttgtcaaa aggggttgga ttcctggctc 235441 tcctcatctc catccaagct attaacttat catgatagcg ctttcttaaa ttatcatagt 235501 ccggagcgaa tgtaaacggg taattttcaa attgggcctt agggaagtga atattatcct 235561 tttactaaat gcaattatat ttttttacta gtaacataaa aatctggagg gaggctgttt 235621 aaagatggat gaattagata tcgcattctt tattttaccg ttaggaatta tgctgctatc 235681 gattgtcggg acctgtattt gtaaaaaccc gtatctgatg ccaatgctta gtttggtgat 235741 ttctcttgtg ctcaccttta ccatttttaa tcaatcattt ttgggatggg ctgttgtcta 235801 tagcttggtt tctctggctt tatcctatat cacattgatt gtggtaagga aaaggaagga 235861 atcaggaaat taaaaagacc tcactttcta acatatcgtt gactaaagca actatatgtg 235921 attataattg ctttagtcaa cgatattaga aagtgggaat tgatttgaaa acaagagaat 235981 catctgtcgg gttaaaattc agaaagttca atcgatttta tacaaacgtc cttggtttcc 236041 ttaatgagca catttacgac agcccgtttt ccttaacaga aacacggatt ttatttgaga 236101 tttataatac gcctaattgt acggcaaaag ctcttcagga taagctgggg cttgaccggg 236161 gatatgtcag caggattgtg aagcagtttg aaaaagaaga tttgatttat aaacagagga 236221 gcaaagatga cgcccgccac cattacattt ttgtcacaga aacaggaaaa acgatttata 236281 aaaagctgga ggagaaagcc aacgaacaag tagaactgat gctgaaggta atcaaccaaa 236341 aggagcagca caagcttgcc gaggcgatgg cagagattga agcgatcctt tcacagtcgc 236401 tttctgccag agcatcagag atatcgatta gagattattt tctttcggag gatcttcaac 236461 tccttattga gaaacaaaga caattttacg cggaggctca cggttgggat gacacgtttt 236521 tagcttatct tcaggagaca tttgacgctg acatcgaaaa aatatggatt gcggaaagcg 236581 gcgggaaatt tgccggctct gtcgggttgg tcaagcacga tgaaaagaca gtccagctca 236641 gatggtttct ggttgatgcg gattttcggg gcagggggct tggcacgcaa ttgctggagc 236701 atctggttgc atactgccaa gacatgaagt ttgaccgcat tttcctttgg acggtgagca 236761 cgatggctga ggctcgtccg ctctataaaa aatttggatt caggataagt gaagtaaaac 236821 aagaagcgcc attatgggga cagcagctga cagaagaacg gtgggatttg gagctgtcat 236881 gaaaagactg cattatgcgt ggatcatcgt ctccgtcacc tttttgatct tattggcggt 236941 tcagggggtg cggctgtcgt ttggtgcgtt tgtggagccg tgggaacggc agttttcaat 237001 cgatagaagc accatctcgc tgatttcgac ggtgagtttt attgtttatg gcatatcaca 237061 gcctgtgatc ggtcggcttg tggacaaatg gggtgcccgg gctgttttgg catggagtgc 237121 gttactgaca ggagtcagca ttttcttaac ataccttgtg acttcgcctt ggcagctgtt 237181 tttgctttac gggctgggtg tctcgcttgg agtgggcgga gcatcgaatg tggcggcaag 237241 tgtattggtc gtcaattggt tcagcaaaaa gcggggacta gcctttggga tcatggaagc 237301 aggctttggc gcggggcaaa tgcttctcgt tcccggctca ctcatgttga tccattggtt 237361 tagctggaag ctgacggttg tggtgttggg actgctgtta atcgtgattg tctttccggc 237421 tgcgctgctg atgctgcgga acaatccttc agaaaagaat acagagccga taggcggact 237481 ggctgcatca gaaaaagaaa cagcacccaa aacaacagct ctttcagtgg ccgggatgtt 237541 tcgtatgagg caattctggt tcttgatttt tccgtttttg atctgtggat ttacgaccgt 237601 ggggctgatg gatacccatt tgattccgtt ttctcatgat catggctttt caacgacagt 237661 cacgagtgct gctgtcagtc tgctagcagg ctttaatatt gctgggatct tgctgtccgg 237721 aattgtagcg gaccggtgga gcagccggaa aatcctgtgc attttatatg cggtgcgggc 237781 gctgtcgatc gtgattctta tttacagcca cgagccctac ttgcttttag cctttgcgat 237841 tctgtttgga ttagtggact ttgcaacggt agcaccgact caaatgctcg ccacccagta 237901 ctttcaaaac tactcgatcg gcctcatgat tggctggctg tcactcgccc atcagatcgg 237961 atcggcacta ggtgcgtatg tgcccggcgt catctacacg gtaacgggtg agtatacact 238021 ggctttttat ttgtcgattg gaatgctcgt gcttgcgagc gtaatgaatg tgatgctgag 238081 ggagccagct gcggttacgc gtgacagtgc ggctgtggta gacaagtgat gaggacaaag 238141 ggaaagcatc tctgatttcg agattattca gagatgcttt ttttgtattt ttgttctaat 238201 acgaagtcga tcataccgac tatgcgggcg ttttcggatt tttgtttgaa gcgttcagaa 238261 atttgaactt ttcttgaaaa tggggaaaca ataaaaaccc aaaaaaggcc gatcaaggca 238321 aaaaacattt gtacagctaa ttctattaat tcattaaaac gagtgctgaa aaaatagaag 238381 tataacgtta ttaatgtcac agtacatacg attttggcaa gtgtgtttga atgtaagcaa 238441 tggttcacta aagaatacct ttaattgatt cagcatgatt gaatcatatt tgtttaggaa 238501 aataagaagt tctttatcat cttttttatg ttctaaaata aagttgctgt ttctgtttct 238561 ttatatgtat ggtggtctac attcaatata tacatctctt aaagtataaa aattgagtat 238621 ttcttagtaa ggatgaaaca aaattacatg atttttttgt tatatctttc agttagaata 238681 aaatctataa ctcctctcat tcgcaaatat tcggctctct gtgcaaagtg cagaacagta 238741 tgtaattgtc cttttctaga tatatttaaa agctttatca aatcaataag gattttcaag 238801 aaaataatta ataatagaaa gataaaaatg tgtggtatgt caatgtaatt gatttgtcct 238861 gaaaataaag aagttgcata gacaacaata atacttccgc aaaacatcaa actcatataa 238921 tgtggaaggg aaaatggacg agttgaaaaa tatgctttta attggcttag catagcatta 238981 tctcttgtat ctaagtagcc caaaagctct ttatcatttt tactaattgt aagaacatga 239041 ttcaatacag cactaaaatt cattgaatct tcattatcag aggcagtatg tttattagcc 239101 tgtatgtttt gttgatccat tttatatttt ttataaagta ttgtattaat taacttgttt 239161 ttctcataga attcagatcg ttgattaagg gatgcttttc ctttgttttt atttcctttt 239221 tttatgattt tagtataagt cataaaaata caaatgactg taaaaataga aaacactgca 239281 ggtgaaatat ctgaaagaat agtattggtg aagacttctt ttgcttggat gaaaaggaaa 239341 gaagctaaag tcatagatat aaacatgcat aaaactgcta ctttcacaag aaactgaagc 239401 ggaagagaag gttccgaata atagtgcttc aactggttga gtgtcagaga atcttggcga 239461 aaaagataat ctattatctc ctgctgattt tgcatctgat tgatatcatg agcgatgttt 239521 tttgtttttt caaaaactat ttgatcattt ttcatttttg ataaacctcc aaaagacgat 239581 agataaacta aaaaaactgc atgagcatat tttaacttat gttcatgcag ttttgtatta 239641 aagttagcta gtataataag caaaaatggc cagtaacata gcagataatg cggtagcgac 239701 tttgactcct ttattgttcg ttaaatcact gcccatattc ccaattagta aaagtgcagc 239761 aacacctaca acagggaata aatattgatc ataagacggc caatctaacg ctaattcact 239821 ctcgggagac gtaactggta ctcccttgta cgtctttatt ttaaacgtaa tcgtagtcgt 239881 tagtccagtt gtgacattgt caccgactgg aatatcaggt gtatagattt taatttgaat 239941 gtttaaagat tcagctgttg gatttacata aacctccaaa taaccgttgc gtactgataa 240001 gctcagacta tttaaaaggt tttgataaga gtcgatttgt gacgcagtga gagacgtttg 240061 agtgtcgccc aataaacccg tgatataggc acctggttta ccatttgtaa tggtaattgt 240121 gtttggtgaa ccttcacttg gtatggttgc cagaagtgaa gttgatagaa taatatccaa 240181 ctcaggtgat gtgaaaatgg tttctgtcgt atcaaattca aacatcgcgt ttgccagact 240241 tgttagattt tctaaagctg gaatggtaga taaaatgtct gtcagtgtac gcagtcttgc 240301 atcatatacc ggatcagacg gcggatttac attgcttgca cctgagtctc ttcctgaata 240361 cccgtcttta tcaatcccga tgcttccaga gccgcttccg atggttcctt cataaaattg 240421 atcaaaggcc cagttgtttg gcatcggata gccgagattg ccgctaaatc ctgttgacat 240481 atttgccaca aaactatact ttgtcagtcc tgcttcagat gtacggatac aaatgtttct 240541 tggtccgtaa acccctattt catacttagg tgcggttgaa aatgtctgca tttttgtaaa 240601 tgctgactta atctcttgga aataaggaat gattttatcg gtcacttcat aatcgtatgc 240661 atcaaaatcg acagcgaaat aaatggtcgt gcctgacgga aaacctaatc ttctagcagc 240721 agaagcggca ctatatgcat ctcttgtgcc ttggtctttg acaaaataag aagattcata 240781 gccgccgtct tgataaattg ggaaaacctt caatccggca tcaagaataa ctgcaagctc 240841 tttagatgtc agggctttag atgtgaggcc gctgcttgtc cgcacatttc cggtcaaata 240901 tctgccaacc gttttataac cgttattccg cagtgtttga gctttttctg cggttataat 240961 tgtagcagtg tcacaagcag aagcggtgcg agttgtgtct cctgagcttg ataataaagc 241021 tttaatggtt ggcatatctg cataacctgt ttgcggcagg cacatgaact cttgaaatgc 241081 tttaacagct gaaacaacac ccacaccata tttgccgtca aactcaccag gatcgaacga 241141 ttttccgtta caatagaggg cgtactgaac aattaagaca aatcctgttc ttgaatcgcc 241201 gggagttaaa gtagggcaca aacttgtggt gccgtttccg aaaaatccat tggcaacact 241261 tgtgctcatg ccttcttctt tttgcagggc ataaataaga gctttatttg tatcgcggcc 241321 atacagtccg tcacaaggca ttaacccgat atagtcattg tagtctcgat ttaagttttg 241381 ttgaatctgg cgaattcttg aatcaccccc agacaccagc ttaaaagcgc tcatgtctaa 241441 taaggctttc ataattaacg tggtgacaat cccatcctgt gttgtcagtc cggcagcttt 241501 ttgaaattct tttaccgcat tttctgtttt ttcgtaaaag acgcctgtaa aaccgccggg 241561 attaaagcct ttacaccata aagccccttg taaaataaaa ttcatgttgc ttggttttga 241621 atctggagct tggcgtttaa gaggcttaaa taagcgctgt gttgtcggcc cgaagttatc 241681 ggctggctct gagataccca attcaatttg aagcgcccga gtcagaccgt agatcgtatc 241741 ccacccagtt ttcccgcttt cttcaactgg gttataccca tgtttgccgc tgtacgtatc 241801 gttcagccat tgctgtgtga ttaagaccat ttcatcaacc atttcgattc ctcctttgtt 241861 agattgcgtt catttatagg tggcaaacgt aggacaaaat aaaaaaatgg atgccgttaa 241921 gcatccattt tacatccgtt ctccaacagc ttcgctttcg gtttcagctc tgaaatgtag 241981 aggcctaaaa gtgtaagcgc gcctcctaga agagcgatcc atgtcatgtt ttcgtgcaga 242041 atcaggacag aagcggcgat cgtgataacc gggaccatgt aaatatacgc actggatttg 242101 acggctccga gcactccaac tgaataattc caagtggcga agcacagggc agaagcgcca 242161 atccctaaga aaagcatgtt gagtatattt gaagcagatg aaaatcggct taggtcaaaa 242221 tggaagtcga acaaaaataa agcgggaacc ataaacaata aaccatacaa aaatactctc 242281 tgtgtcagct cgatgatgtg gtattcgtag gcgcttaatt ttttcatgaa tatcgagtat 242341 ccgccaaaca cgagagcagc cccggctgcc atgatgtctc cgagcggatt tagacgcagt 242401 accacattgc cgttaaacgt aatcaataaa agcccgatca gtgccgagat aaatccaatc 242461 aaaaaagtca gacgcaattt ttcgccttcg agcagaaaat gggccaaaac cgcagtgatc 242521 atcggtataa tggacacgat catgccgaca ttggaggcgt atgtataggt gagagctata 242581 ttttctaata gaaagtataa ggttacgcca aataaaccag ctccggcaaa caacagctcc 242641 tgccgccaat ttctgaacgg aatcatgttg ggacggacga ggataagagc gataaagccc 242701 atcaaaaacc gataaaataa tatttccatt ggagagaagt cagccagcag aacttttgtc 242761 gaaataaagg tcgtccccca aatcagaatg gtcacaatgg ctgcgatatg ccccgaagtt 242821 tctctttgta tgttcatctg tgaagctcct tttcaaaaat cttcatgtat tgcttcggcg 242881 tcagccccac ctgccgttta aaaaacttcg tcatatgact ctgatcgctg aatcctgtct 242941 gaaatgccgc atcaatcggc cttacccctt gttcaaggag ttttttggct tgattaatcc 243001 ggattgtttc catgtagcta ttaggggtaa tgcctttttg ttttgtaaat gaacgcaata 243061 aatgatactt gctccagcct gttaattcac tcaaatcatt gagtgtaaca ttttcggcat 243121 aatgctcttc taaaaattca caaaccattt tgacttcgtc tgatggttct ggaacgctgc 243181 taaggaacgt gacatctgaa taatggcgga tcagctcctc taatagatga agaaacagct 243241 cctccttacg caaagcttgt ttttcctcgg atatcaaaat atgcaattcc tgcaggctgg 243301 ctgtcagctc atggcggaat aacacatgct gggagaaata agggagatgc ccggagccag 243361 taatctcttt caccgccttc tccatgatat ccggcatgac attgatacac cgataatcaa 243421 gcgtccggcc gtcaatctgt tcacagctat gcgtgtcacg ggggttaaag aggagaagat 243481 cacctggatt gatgatatat tcttgatcct gacaggccag ataccgttgc cctttttcaa 243541 taaatccaat cacataataa tcgtgaaagt ggttcgggaa cttctgcata attcccttga 243601 agcggtaggc ttctatatga aggtgtgggt caagctgcag tgtgcgggtt tcgttttgca 243661 tgggatgcct cctgtcggtg tggtggtctt ggattaagtg tagcatgatt ttgggggatt 243721 tcttgtatga tgttgctgtt taggaataga gaaagcagac cgttatttgt ctgctttcgt 243781 ttaagaattt aaaagatttt aaccctcaat aataatttta tcttttttaa taaaaattta 243841 tttttcaaat atttcagtta taatggtttg gaacagatag gaggggcaaa gatgtatcaa 243901 tcaaagaagg ttttattgtt aggttcaggt gaattaggta aagaggtagt gattgaagcc 243961 cagcgtcttg gggtacagac ggtggcagtt gacagttacg agcatgctcc ggcgatgcag 244021 gtcgcgcata acagttatgt cgttgatatg ctggacccag agcagatcag aaccatcatt 244081 gagaaagaaa atccggattt gattgtgcct gaggttgagg cgattgcgac ggatgaattg 244141 ctgaagcttg aagaggaagg atttcacgtt atcccgaatg cccgtgcggc caagctgacg 244201 atggatcggg aaggcatcag acgacttgcg gcggaaacgc ttggacttgc gacagctggc 244261 tatgaatttg cgaatacata tgatgaattt atacaagcgg cagctcagat cggttttcct 244321 tgtgtcgtta aaccattgat gagttcttct ggaaaaggcc aaagtgtgtg ccgctctgaa 244381 gcggatttag agagctgctg ggagacggcg atggaaggcg gacgggtgaa aaacggccgc 244441 gtgatcgttg aggagtttat ccctttcgaa tcagaaatca cactcttaac cgtacgtgcg 244501 gttaacggta cggcattttg tgagccgatc ggtcatgtgc aaaaggacgg ggattatatc 244561 gaatcgtggc agccgcatga tatgacagag cagcaaatag aagaagcgaa gcatattgcg 244621 aaaacgatca cggatgagct tggcggatac ggcctgtttg gtgttgagct gttccttgcg 244681 aaagataggg tatatttcag tgaggtatct cctcgtccgc atgatacggg tcttgtcacg 244741 ctggtgacgc aaaatttgtc agaatttgcg ctgcatgtcc gggcgattct cggctttccg 244801 attacagaaa tcacacagct ttctcctggc gccagcaggc ccctcaaagc gccggaagaa 244861 ttagcggatt acactgttga aggattggaa aacgcactgg cagtcccaaa gactcaagtg 244921 cgcgtctttg gaaagccgat aacaaaagcc ggacgtcgta tggcagttgc gctttctgct 244981 gctgattcag ttgaaacggc aagagagaat gcaaagaaag cgttggacca gctaatttta 245041 aaatagagtt tgaacaggtc ttgtcatggg acaaggcctg tttttttctt tctccgtaaa 245101 agttttatca taagaatcag aaacctgatt ataatgtaaa agtcttccat cgatacgggt 245161 ggttgacact aaaggaggga gatgacaaaa tgaaattagt tccaagattc agaaaacaat 245221 ggttcgctta cttaacggtt ttgtgtttgg ctttggcagc agcggtttct tttggcgtac 245281 cggcaaaagc ggcagagaac ccgcaaactt ctgtatcgaa taccggtaaa gaagctgatg 245341 ctacgaaaaa ccaaacgtca aaagcagatc aggtttccgc cccttatgag ggaaccggaa 245401 aaacaagtaa atcgttatac ggcggccaaa cggaactgga aaaaaacatt caaaccttac 245461 agccttcgag cattatcgga actgatgaac gcaccagaat ctccagcacg acatcttttc 245521 catatagagc aaccgttcaa ctgtcaatca agtatcccaa cacttcaagc acttatggat 245581 gtaccggatt tttagtcaat ccaaatacag tcgtcacggc tggacattgt gtgtacagcc 245641 aggatcatgg atgggcttcg acgataaccg ccgcgccggg ccgcaatggt tcgtcatatc 245701 cgtacggtac ttattcaggc acgatgtttt actccgtcaa aggatggacg gaaagcaaag 245761 acaccaacta tgattacgga gctattaaat taaacggttc tcctggaaac acggttggct 245821 ggtacggcta ccggactaca aacagcagca gtcccgtggg cctttcctcg tcagtgacag 245881 gattcccatg tgacaaaacc tttggcacga tgtggtctga tacaaagccg attcgctccg 245941 ctgaaacgta taagctgacc tatacaaccg atacgtacgg ctgccaaagc ggctcgcctg 246001 tttatcgaaa ctacagtgat acagggcaga cagctattgc cattcacacg aacggaggat 246061 cgtcatataa cttgggaaca agggtgacga acgatgtatt caacaatatt caatattggg 246121 caaatcaata aatacagcaa actagccata ttcatgtcta ttttgttttt atgcgggtgc 246181 agttcgcaga cgcattcttc tcaaaaagaa acgactattc ctgtcactct tcatgtggag 246241 gatgctaagg ggctgccggt cgaaggggtt caagtgacga ttgtcaaagc gccctcttca 246301 gatgaggagc cgagtacaga gattggcgag atactcggta aaacagacaa aaacggagat 246361 atcaaatggg ataccggcag aaaaggcgat tactcagtcg cgttgacgaa gggtgaaaca 246421 tcagtaaccc atcacatctc gttaacagag gataaaaaag atcatgccat tccattagtc 246481 ttcaaagaat agcagtttcc ttgattttaa gggaactgcc ttttttattt attgcaggaa 246541 accaaactat atactggaaa tttattatgt gagataataa gaaataggta ttttttctta 246601 cgagacaaaa ggggcgttat cctttatatc aatcaaaccc ggaggaaaaa gaagaagatg 246661 atacaagatt caatgcagtt tgccgcggtt gaaagtggtc tgcgctttta ccaggcatat 246721 gatcaaagcc tttctttgtg gccgattgag tcggaagcat tctatgtttc tactcgtttt 246781 ggaaaaacac atatcattgc aagtgggcca aaggacgcac cttcgctcat tttgcttcac 246841 ggaggccttt tcagctctgc gatgtggtat ccgaatatcg cagcgtggag cagtcaattt 246901 cgtacatatg cggtcgatat aataggagac aaaaataaaa gtataccatc agcagccatg 246961 gaaacgagag ctgattttgc agaatggatg aaagatgtct ttgattctct tggacttgag 247021 acggcacatc tggccggcct ttcgcttggc gggtcccata tcgtgaattt cttactccgc 247081 gcgcctgaaa gagtagagcg ggcggttgtt atcagtcccg ctgaagcgtt tatttcattt 247141 catccggatg tctataaata cgctgcagag cttacagggg caagaggagc tgaatcatat 247201 atcaagtgga tcacaggcga cagttatgat ctgcatcctt tactgcaaag acaaattgtg 247261 gcgggcgtgg aatggcagga tgagcaaagg agcctgaagc cgacagaaaa cggctttccg 247321 tacgtgttca cagaccagga attgaaatca atacaagtcc cggtacttct gatgttcggt 247381 gagcacgagg ctatgtacca tcagcaaatg gcctttgagc gggcttcggt attggtgccg 247441 ggaattcagg ctgaaatcgt aaagaacgcc ggacatctgt tatctctgga gcagccagag 247501 tacgtcaatc aacgcgtctt gtccttttta tgcgggggga taaaatagta aggaacatga 247561 aaagattggc attcattttt caaaaggtaa caaatgttgt ataataatag aatttgaatg 247621 ctgctttttt tgggagcatt ctatgttatc atgcttattg gagaaaaatt tttcctgtaa 247681 cgctattcga tcactatcgt caaataatat agatggtttt acaattggag gtttggttac 247741 actgtgaatt acatcccctg tatgattacg ataggaaact tcatttgcgg attgctggcg 247801 attcattcct tgctatatca caacattcat tcagcagtgc tttttatttt tacaggcatg 247861 ttccttgatt tctttgacgg gatggctgct cgtaagctga atgccgtttc tgatatgggg 247921 agagaactgg attcgtttgc cgatctggtt acgtttgggg tggctccttc tatgcttgct 247981 tacagtgtcg cgttgtatac cctgccattt atcgggatct tatgcgcatt gacgtacagc 248041 atttgcggaa tgcttcgcct ctctaaattt aacattgaac aaagcaagct cccgacgttt 248101 atcggtatgc cgattccgtt tgcgggcatg tgtctcgtta ttctaagctt cacctataac 248161 ccgatccttc tggcaatcgg cacttgcgga ctctcatatt tgatggtgag taaaataaaa 248221 ttccctcatt ttaaaaaaca tgcggcagaa aacctggagt ctgggagatg gaattagttc 248281 agcagctcat agcggattac ggttatctcg ctattttttt gatgctggta ttaggaattg 248341 taggattgcc gattccagat gaagtgatga tgaccgttgt tggctatttc acgcataccg 248401 atgtattgaa ttatgagctt tcgatattga ttagttttgt cggggctttg ttaggtatgc 248461 tgatcagcta catgattggc agaaaagccg gacgcccgtt tatcgacaag tacggcaagt 248521 gggtcggctt aaaagaaaaa agaatgatga aagtggaaaa atggatgaag aaatacggtc 248581 catattctct tattttaggt tattttattc ccggcgtcag acatgtgacg tgctactttt 248641 cggggatcgg caaaatggat ctgaaaacgt atgttgcgtt tgctgcaatc ggcgcctttt 248701 tatggtgctt tgtttttatt acaatcggaa gggttatagg gattattcat gtttaatacg 248761 gctgtaaaga ttctgtatcg atcattgata gagctgacga atcatcgtct gtcatcctat 248821 ctgattaaag gattttgcga gtcgaaaatc agcaaaccgg tcattccgct tttctcaaaa 248881 cattttcggc tgaattggga tgatgtggac ggtacggctg ctgattacgg atcgctgtcc 248941 gaattgttca ttcgacaaat aaatctggag cggcgccctg tgtcaaaaga ggcgcatgcg 249001 gtggtcagcc ctgttgacgg tgtggttcag acggtaggaa tcatcaaccc gaatcaaacc 249061 tttacggtga agggaaaaga ttactcattc gctgagctga ccggctgtaa aagcgcagac 249121 catcaataca acggcggata tttcgtcgtg ctgtatttaa gcccgaggca ttatcaccgt 249181 ttccattctc cgatcagctg caggtatcaa aagctggccg agctcggaaa tcgctcatac 249241 ccggtaaatc aactaggctt aaaatacggg aaagatgtgc tgtcgaaaaa ttatcggttt 249301 gtgtacgagc tgaatagcgg cagccgaaat gtcctgatga ttcctgtcgg cgcgatgaat 249361 attaattcta tcgtgcagac gaatacccgt actgaattgg agatcggcga ggagctggga 249421 tacttttcat ttggctcaac cgtcattttg gtttttgaaa aagacgcgtt ccagccgtcc 249481 gcccatttag cagaaggcca agaagtccaa gtcggagaac tgataggtta cgaagaataa 249541 aaagaggagc ttgcataaac gcagcgcctc tttttttgaa gaaaggtgag attcatggag 249601 aaacaaatca tcagctggat tacagattat cagaacaccg gagatgaagc cgtcctgcgg 249661 caagtgcgag aagtgtgctg gccgatcgtt gaagcggttt tgcaagagaa agtaatggat 249721 gatgaacaag cgaacaattt gcgcgaaaaa ggaatcgagc ggtttccatt catcatcagc 249781 aaataccaag cggatgtgca gcttccggtt gagacatttt tacaaaatac gtatcggttt 249841 tactttcatc aggtgatgag agaatccagc taaagcttct ttcaacagag aagctttttt 249901 ttgttggcag gaaaaggaaa ctttttctat atctatctcg taatgactag agaacctagc 249961 agaaaaggag agatagaatt gaaacgaatg atagtgagaa tgaccctgcc gctgctgatc 250021 gtttgtctgg cgttttcttc tttttcagcc tcagcccgtg ctgcttctga agaaaaatat 250081 tgggatcact ggattgaacg acatgcacag cctctggatg cttccaatgc ttcaaacaaa 250141 gaccttcgat ttctaaaaaa ggtgctgaag ggaaaacgaa tcgttcagtt aggagaaacc 250201 acacacggtg ctggcgaaat caatgccaca aaggtcagaa tgatcaaata cctccacgaa 250261 gagctgggat acgatgtatt ggcctttgaa tccggctttc ctgatacaaa tgcatcctac 250321 cttaatatgg accaattaac ccctaaaagc acgatgaaaa actccattta cgctgtatgg 250381 cacacagaag atgtcgtcga attgtttgat tacatgaaag agcaaaaaga gaaaggcgat 250441 ccgctgatcc ttaccggttt tgatattcaa agcatgaaga attcattcaa tgtagctgcg 250501 actcaatggg taaaagcggt ggaccctgag aaagcagagt tgctctccca atcagaaaat 250561 gatttttcaa cattagtgac agacagcaat acgtttgatg aattttcgca aaagaaggaa 250621 aagcttgtga aaaactatca gaagctgatc aagttcacta aaacacatgc ttcagagcta 250681 aaagaaaacc ttccaaaaga gccgaaagct tatgagatgt ttatgcattc tcttcagctg 250741 agaattgacg taatggaaac atatatgctg gaagaaatga aagaaaaact agaggagtat 250801 ccggagaata ttgaggattt ttcattcttt atgagagacc gcatgatggc tgaacaattt 250861 cagtgggtag ccgacaccct ttatccgaaa aagaaaatca ttgtctgggg ccacaattac 250921 catctacgca aacagaatac gaagatgata aaggactggg tacagctaaa cggccctaac 250981 atgggtgatt atttgccgga gcggctgaaa aaacaaacat atacgattgg catttatgct 251041 tactcaggtg cgagtcttga tagctccgat aataagactg ttaagccggt tacaagcccg 251101 ccgccgtctg ggagccttga agctttgctg aaagcggcgg accgaccggc tgtttttgtt 251161 gattttctcc atacaaaaaa caagaaaggc acttcgtgga tgtatacccc gcggactgcg 251221 ctctattggg ggtacatgga agagcagatg atcctgaagg aacaatatga cggtgtcatt 251281 tggctggagc atatcacgcc ctctgtcatt atcaagtgag cggtgtcccc tgtggtaaac 251341 aggggatttt tacatatcgc aaaaataatc aaaacatata atccgtgatc cattattcta 251401 aaacagaaag gagattggag cgtgcaatgt attatgaaaa agctgtccag aaaacaatca 251461 attggattga atcacattta catgagcaaa tatcaaacga ggatattgtt aacgtttcaa 251521 gcttttcaaa attccatttt catcggattt ttcaaaaaga agtcggcatg tcggttgctt 251581 cttatattcg gttaagacgt cttgcgaatg cggcggcagc tttgctttat acagatcatc 251641 gtattatcga tattgctttg tattatcagt ttgaatctca agaagcattt acgaggacgt 251701 tcaaaaagat gtatcacatg ccgccaggag cataccgaac atttatgaaa cgctttactt 251761 caaaaaagga ggaatcttac atggagaaaa aaatgaaagg ctgggtattg agcgggagcc 251821 atccgttcca attcgaaatg gggattgacc gggaaaatgt acatcaggga aaagcttcag 251881 ggtatttaaa gtcaacgatg gttcaggata tcggtgaatt tgcgacgatg atgcagcaat 251941 tcaaagcaga tcgctatcta ggaaaaaggc ttcgtctatc aagttttatc aaaacaaagg 252001 gggtgcagca ttttgcctca ctttggatgc gggttgacag tgctgctgat gatgttctcc 252061 aatttgataa tatgagcaac agacctatta ccggaacaac caattggaat cattatgcta 252121 tcgttttaga tgtcccagaa aatagcgctg tgatatcttt tggcgttcaa ttatctgggc 252181 cgggtcaggt gtggatggat catgttgttt ttgaagaggt agatgagagc gttccttcaa 252241 caaaccttga aatgccggga gaacttttag atgaaccggt aaatttatct tttgaagagg 252301 aactacaaaa atagttttca gacaactact tttattagtg agttaatgga aaatactatt 252361 tgttattaat aaacccttgt gctgcttagg tttgtaagag cttggatatt tttatcagtc 252421 tgggcggatc tgttcatctt tgcggcattt tcctgtatga tatagtaaga gtgtgcatag 252481 caactaacta taattgaaca gggtgtttaa aacatggaaa aacaatacag agtattactt 252541 tactataaat atgttccgat tgaagatcca gaggcgttta gagagcagca tctggctttt 252601 tgtaaggagc ttggtttgtt aggccgtatc cttgtttctt ctgaaggaat taacggtacg 252661 gtatcaggta cggttgaaca gactgaaaaa tatatggaaa caatgaaagc tgatcctcgc 252721 tttgcggaca tggtatttaa aattgatgaa gcagaaggcc atgccttcaa aaaaatcttc 252781 gtccgccata aaaaagagct tgtaacgctt cgtcttgaag atgatgtcga tccgaacgaa 252841 acaacaggcc agcatttgaa gcctgcagaa ttttatgaga agatgcagga tccaaacaca 252901 attgtcatcg acgcgcgtaa cgattacgag tatgaccttg gccatttcag aggtgcggtc 252961 cgtcctgaca tcgaagcctt ccgtgaatta cctgaatgga ttgaagagca caaagatatg 253021 cttgaaggca aaaagatttt aacgtactgt acaggcggcg tgcgctgtga aaagttctca 253081 ggatggctgg tgaagcaagg ctttgaagat gtagctcagc ttgatggcgg aatcgtgaca 253141 tacggaaaag atccagaggt gcaaggcaag ctttgggacg gccagtgcta cgtatttgat 253201 gaaagaatca gcgtgcctgt caaccgtgtc gagcatgtga ttgtcggcaa ggactacttt 253261 acaggagaac cgtgtgagcg ttatgtgaac tgcgcaaatc catcttgcaa taaaaaaatg 253321 atatgcacac cggaaaatga gtataaatat atgcgcagct gcagccacga atgccgcacg 253381 aacccaagaa acctgtatgt gaaagagcat aatatgacag aagaagaagt aaacgcaaga 253441 ctggcagcga ttgaaacaga agatcacgct gctgctgaat aaaaaaagaa cacctcgtat 253501 tgaggtgttc tttttttcta tatgctttca gtttggctgt ttgcggaaac ccattctttt 253561 tggcggaagg ccttttccca ttttgatacc acgatacagg cgatcgcatg tcccggtacg 253621 ttcacgcctg ttctcgccat gtccatgacg cggtcaacac ccgcgataat ggcaacgcct 253681 tcagccggca gtcctacagc attggcagtc gccagaagaa ctacaagcga tcctgagggt 253741 acagctgcaa tgcctttact ggtcatcaca agcacaagca tcatgagcag ctgctgggac 253801 aatgtcatgt ctacttgaaa ggcctgtgcg agaaagatac aagaaaccga taaatataag 253861 ctggagccgt cacagttcaa tgacaagccg gagggaacga caaatgatac cactcgtttg 253921 ggacagccgt atttctccat tctatccatc agctgaggga gaatggtttc agtgcttgtg 253981 gtggaaaatg caattaaaaa cagatcccat atcattttca atacttcgaa atacttaatc 254041 tgaaagatga gaccgacaag cggaaagagg acaaagagga tcaggaacag gccaaggaat 254101 acggtgccaa ccagcttaaa catagggagg aggagttcaa tgccatattg gcctacagaa 254161 gcagccatca gggctaacac gccgatagga gcagtgacca tgacgatttg cgtgagcttg 254221 aacataatct gagctgtaga ttcaaaaaac ttcattactg gttcagaagc tttgccgata 254281 ccagctgcgg cgacaccaaa taaaatggcg aagaaaataa cggcaagcaa atcatttctg 254341 gccatgacat caataatgtt tgtagggata atatccagga tcatttgctt gaaatcaaca 254401 actttgtctg tgtagccgga aagttcatga atatcttttt ttgccaaatg ggagaggtca 254461 agcccgacac ctggttttaa gacattcgct aataaaagtc caagccctaa taccaacgtt 254521 gtaatcactt cgaaccaaat gatcgtcttg atgccgagac tgcccatttt tttcatgctt 254581 ccgcttcctg cggctccaat gacaatggta gaaaatacaa tcggcacaac aatcatttta 254641 atcaggcgga taaatccatc tccgacaggc ctcagtgcca tcccgaaatc aggaaaaaag 254701 tggccgatca ccgcgccgac agccaaagcg attaaaattt gaaacgcgat taattttttc 254761 aaatgaatcc ccctttagaa cgatagaatg taggcatatt catatcattc gtgattcaaa 254821 tgcaaacacc ttttttcaag ttattttatt ttgacagcgc tttcattatg ttggcgaaaa 254881 agtcccccgc agcagggggg acttttttac ttcatttgaa tgtgctttag atcttcttca 254941 gaggtatttg tgaaaataac cggtgttatg gctgaagcgg catgctgctt gatgtaattg 255001 agatcaaagg tgagaagcag ttcgccttgt ttgacggctt gtccgcttgt gacatgtgct 255061 tcaaagcctt ccccattcag tttgacggta tcgatgccga catgaatcag gatttcagtg 255121 ccgccggcgc tcataaagcc gatggcgtgt tttgtcggaa aaatcgagac gatctcgccg 255181 tccgcaggtg caacgacttt tccttctgat ggtataatcg caaatccctc gcccatcatt 255241 ttttctgaaa agacctgatc aggcacatcc cctaaagaga ctgtttctcc tttaatcgga 255301 taaataaagg tctcatcgga atcgggcttc agcggtttgt cagttaccgt gtccagcgcg 255361 gcggcggtgg cagggacgcc tccggccatg attgttttga tgtcgtcttt taaggcatcg 255421 gacttggttc cgaatattgc ctggaagttg ttgttgacct ccagcacacc tactgcacca 255481 agccgtttta attcatcctt gcagacttgg cttggctgat gaacggtcac acgaagcctt 255541 gtgatacatg catccaggtt agcgatattt tgctgtccgc ccaaggcctg cagcacgtga 255601 aaggcaagct ggtcttttgc aactggagct ttctcctcat tctgaccgtc ttcatctgtc 255661 tcacggccgg gcgttttcaa attccatttc agaatcgcaa atcggaacaa ataataataa 255721 atgaaagcaa acacgatccc gacaggaatg acaacccagc cgtttgtaga cagtccgtag 255781 ttcaagacgt agtcaattcc tccgcctgag aacgtatagc cgtggcggac atggaataaa 255841 tcacaaacga caaagatgac gccggcaaga atagagttaa tcaaatagag cacgggcgca 255901 acgaacaaga aagaaaactc aaccggttct gtaattccgg tcagcataga tgtgagcgcc 255961 gcagaaatca tcacgccgga gatcattttt ttcttttccg gacgcgcggt atggataatg 256021 gcaagagcaa cggccggcag acagaaaatc atgtaaggga aatcccccat cataaagcgc 256081 ccggctgtcg ggtctcccgc gaaaaacctt gtcaggtcgc cggttacggt gttgcctgtt 256141 gatgggtctg tgtattctcc catcataaaa tagaaaggcg tataaaaaat atgatgcagg 256201 ccaaaaggaa tcagcaaacg atagatcgtt gcataaaaga acaggccgac tgttgaatcg 256261 gcaattaaac tgctggctgc gttaattccg ttttggatca gcggccaaac gaatgagaaa 256321 atgacgccga tcaccaatga actgacggaa gtaatgatcg ggacaaagcg ttttccagag 256381 aaaaatccaa ggaccggatg cagctcgatt gatgaaaatc gcttatataa ataggcggcg 256441 agaagcccga taatgattcc tccgaaaacc cccatatcaa tcaggtgctc ggctccttca 256501 tacggaggct gaaggccgag taattttccc atattgtcga gggtgacggt taaaattaag 256561 tatccgatga cagcggcaag tccggctaca ccttctccgc cggctaatcc gatcgcgacc 256621 cccacggcga aaatcagcgg aaggttatcg aatacaacgc cgcccgcatc ctttataata 256681 gggatgttca gtaaatcctt gtctccgaaa cggagcaaaa gacctgctgc cggcaggacg 256741 gcaaccggag tcatcaacgc gcggccaagc tgctgcagaa tttgaaatgc ctttttaaac 256801 atgacagtct ccttttattg tgttatgaga atgatgcact ctttaatttt tgagctgctt 256861 tataatcggc gataacggtt acatgattgt gtttttgaag aatggaggct ggtacatctg 256921 tcgtgacagg accttcagcc atcttttgaa tggcgtctgc tttttcctcg ccgcttgcta 256981 aaagcacaat atgtttgctg aattccatga tggttttaat gcccattgaa atcgcgagtc 257041 tcggaaccag caccggatcg ccgccgaaga atctggcatt tgcctgtatc gtgctttccg 257101 agagcttcac aacacgtgtc cggtcttcaa aatcagatcc cggttcatta aaaccgatat 257161 ggccattggc gccgatgccg agaatttgga catcaatgcc tcccgcctgg cggatgagat 257221 cctcgtatac tttgcatgcc gcctcaagct gcggattgtc tccttgcggg atatgaatat 257281 gatcaggctg catattgata tgctgaaaaa gatgctcatg cataaaatgg ttataacttt 257341 gcggatgaga tggagagaga ccagcatatt catccaaatt aaatgtagta acctttgaaa 257401 aatcaatttc gcctgcctga tagtctgaaa tcaactgctt atacaagccg accggtgtgc 257461 ttcctgttgc caggccgaga acggcatctt tcttagcttg tatttgttct ttaataatgg 257521 cagcgcttaa cttacagagt tcttcgtagt gctcggcgat cagaatcttc atgtgacacc 257581 ccctcaaaga gatagacaag caccatattt gttatgacca atttatgata cttgtcatta 257641 cgaatttagc accgccctta tcaaactgtc aatattaatt tctgaaaatt tgttataaaa 257701 gaaggataca aatctttcat attgggaggg caaatggtat tatggtctca atgaaaaaga 257761 acggattgca tacagaatgg ggagaatgaa atgacagctt tatattctgt tatcaagttt 257821 aaaatcattg agttaattaa atcgggcaaa tatcaggcga atgatcagct gccgacggag 257881 agtgagtttt gcgaacaata tgatgtcagc agaacaactg tgagactggc tctgcagcag 257941 ctagagcttg agggatatat taaaagaatt caaggaaaag ggacatttgt atcggcggcc 258001 aaaatacaaa cgccgattcc gcataagatt acgagctttg cagaacaaat gagaggactt 258061 cgttctgaat caaaagtgct tgagcttgtg gtgattcctg ccgatcattc catcgccgag 258121 cttttgaaaa tgaaagagaa tgaacctgtc aacaagcttg tcagagtcag atacgccgag 258181 ggggaacctt tgcagtatca tacctcatat attccctgga aggcggcacc ggggctggcg 258241 caggaggaat gcaccggctc gctgtttgaa ttgttaagga caaaatacaa tattgaaatc 258301 agcaggggca cggaatcgat cgaaccgatt ttaacggatg aaacgatcag cggacactta 258361 ttaaccaatg tcggagcgcc tgcgttttta tcagaatccc ttacctatga taaaaatgaa 258421 gaagtggtgg aatatgcgca aattattaca cggggagacc gaacgaaatt caccgtagaa 258481 cagtcatatc attcataaag caatgtgttt taagaaggga atggtggttc tatgttttta 258541 tttacgaatg gaaaagtgct gtggggagca gtgattgctg cattcatcct ttcaattgta 258601 ttttaccctt ttctgccgac gcagatgccg attcattatg atgttgcgaa cagtccggat 258661 ctgacggtta acaagctggc ggggactgtg atgctgcctg ttttgatggt ggtgtttgca 258721 tgggcgcgga agatcaattg gcaatttgta ttcgcagtgt atattttgct gatttgccac 258781 attgtcgtcc tttgtttagc gctctaaatc aaacagccag aataaaactg gctgttttct 258841 ttaatttcag cttcatctga caatgaatgt ggtgtataat agctgatgat cctaaagaat 258901 attctgaaat ttataggtgt gaagcggcgt attattaaag gaaaggctgt atactttttg 258961 cagctttaaa aagactgaat atttaaacaa ttatgtgaaa ggtgtgctga ttagattgaa 259021 taagcttatt gaacgagaaa aaactgtata ttataaggaa aagcccgacc cgtcttcctt 259081 ggggtttgga caatatttta cagattatat gtttgtgatg gactacgaag aggggattgg 259141 atggcatcat ccgagaattg cgccgtacgc accgcttacg cttgatccgt cttcatctgt 259201 ttttcattac ggccaggctg tttttgaagg attaaaagca tacagaacag acgacggcag 259261 ggtgctgctg ttccgtccgg atcaaaatat caaacggctg aacagatcgt gtgagcgcat 259321 gagcatgccc cctttagacg aagagctggt gcttgaggca ttgacgcaat tagttgagct 259381 ggagaaagat tgggttccaa aggaaaaagg aacgtcactg tatattcgtc cttttgtcat 259441 tgccacagaa ccgagtctcg gtgtgaaggc atccaggagc tatacattta tgatcgtgct 259501 ttcgcctgtc ggctcctatt atggcgacga tcagctgaag ccggttagaa tctatgtcga 259561 agatgagtat gtgagggcgg tcaacggagg agtcgggttt gcaaaaacgg ctggaaacta 259621 tgccgccagt cttcaggcac agcggaaagc gaatgaactg ggctatgacc aggtactgtg 259681 gctggacgcc atcgaaaaga aatatgtgga agaagtaggg agcatgaaca tctttttcgt 259741 cataaacggg gaagctgtca cacctgcttt aagcggaagc attttaagcg gggttacacg 259801 tgcgtctgcg attgaattga ttcgaagctg gggcattccg gttcgtgaag agagaatatc 259861 gattgatgag gtgtatgcgg cctctgcacg cggagaattg acagaggtct ttggcacagg 259921 cacggcagca gtcgttacgc ctgtcggtga actcaacatc catggaaaaa cggtgattgt 259981 aggcgacggg caaatcgggg acctctcgaa aaagctgtat gaaacgataa cagatattca 260041 gcttggcaag gtaaaaggcc cgtttaactg gacagtggaa gtgtgaaaat cgaaaaagaa 260101 cctgcccgga ggcaggttct ttttattttg aatgagtcat atcagcagcc ggctggcttt 260161 tgcggttttt tacataatat attgcatagc aaatggccat aaatggaacg ccgcaataga 260221 gtgcgattct ttgattcgga tcaaaggcaa tgccaacgac ggaagccagg cataacagga 260281 acgcagcaat cggcacgaac ggatacaaag gggttctgta tttcaaatca gtaaccttgt 260341 ttcccgcttc gatataacgt tttctgaaca tgaattgaga agcagcgatt cccatccaca 260401 cgacaacgac ggcaaaaccg gaaatcgaca cgagcacaac gtatacagtg tctggcgcaa 260461 atacgctgga cagcaacgac agaatgccgc cgatcatgct gaacaccagc gcgttaaaag 260521 gggttccttt tgacgtcagc tttgcaaatg tcggatgaag cgttttttct tttgataaag 260581 accacagcat ccgggaagaa gcgtagagtc cggaattagc cgctgacagg atcgctgtca 260641 ggataacaaa gttcatgata tcggctgcgt atggtacacc gactctgtca aagacagcga 260701 caaacgggct tttgatgaca cctgcatctt gaatcggaat cagccctgac agcacaaaaa 260761 ttgttccgac aaagaagagc gagagacgcc agaccgttgt ttttatcgct tttggtatcg 260821 tcttgtcagg atcaacgctt tcaccggctg cgattccgat tagttccgtt cccgaaaagg 260881 caaaattgac ggacagcatc gtcatcaaaa tcgggacaaa tccattggga aaaagcccgc 260941 cttccgccgt gaagttggac agcatcggag cggcttctcc gcctttgatc gggatgatgc 261001 cgaacatggc agagccgcct aaaagaataa ataatacaat ggctaatact ttgatgctgg 261061 aaaaccaaaa ttctgattca gcgaaaaact tgaccgaaaa tgcgttaagc aagaagatga 261121 acagcgcaaa gacggcactc cacatccaaa ccgatgtatg ggggaaccag cgctgcatta 261181 acaggccggc tgctgtgaat tctgatccca atgccacggt ccatgtcagc caatacagcc 261241 aagcgaccgt aaatccggtg cccggcccta tgtatttggc tgcataggtg tgaaaggcgc 261301 cggtcacagg catggcgact gacagctcac cgaggcatag catgaccaga tagacgatgc 261361 cggccccgac taagtaggcg agtatcgttc cggccgggcc tgcttgctga atggtataac 261421 ctgagcttaa aaacagcccg gttccgatga cacctcccaa ggaaagcata aagaggtgcc 261481 ggcttttcat acttctctga aaggttgtct cattcttgtt gtgggcagag ttcatctttt 261541 tccaactttc tatcagcgat ttatttcctt cctaataaaa aatctcatgt cagaaagtga 261601 cacgagactc cggcgaaccg gctttaagtt agaatataca aactattccg ataagtcaag 261661 ttgtttttaa agagcgggcc caagccgcaa tttcttgaat attttcgggt tttgtccggc 261721 agcagccgcc aatcagcctc gctccttttt catgccaggt gcgggcgctc gccccgtaag 261781 attctgcgca tgctgcgccg ttccacgttt ttgtttccgg atcatattgc tcacctgaat 261841 tcgggtagac aatgatcggt tttgacgtgt tcttttttaa ctcctctatc aaggaaggga 261901 tatgctgaag cggcgtgcag ttgatgccga gtgctgcaat ttggcggtgt tcatcaagcc 261961 acgatgcgca gtcagctgca ggtgttccgt cactgatatg caagccgtct ttagcactga 262021 agctgatcca tgcatacgtt tcaggaaatt ccttcaacag ccgaacaatc gctttggctt 262081 cagtcagaca cggaatcgtt tcgcatgcca atacatcagc tccggcttca atcagcgcct 262141 tcatccgggg gcgatgaaat tcaatcagtt catcttctga tattgcgtag ttgccgcgat 262201 actcagaccc gtctgcaaga taagcgccat aagggcctat agaagccgca atgatcggtt 262261 ttggccgatt caaacggttc tcttcaagcg accaaaattc atcacgtgct tcagctgcga 262321 tgctgacgga caactcgatg agccggcgtg cttccgcttc gctcagcccg cgtgcggcaa 262381 agccttcaaa tgtagactga tagctggcgg tgattgcaca atcggcgcct gccgcaaaat 262441 aatcagtatg aacttgttta atcagctccg gctcttccat caggattttt gccgaccaca 262501 gactgtcatt caaattacag cccttgcgtt caagctcggt cgccatggcg ccgtctagca 262561 caataagcgg gtatgtatct aatatgtgtt ggataggatt catagaatgt accgatgcct 262621 tctttcagat ttttttgaaa aagatatgaa aatcgtaatg gaggcttacg tgtttgtcaa 262681 taaacgcaaa aagagaaagg tgttcagccc atatgtctga acaccctttt cttatgatat 262741 ttgtttgttg tgcgtgtcag tctttgtgtc tgaaaccggc cagcactcaa tgccattatg 262801 gtttttgagc acatctttat aaaagaccgg atccttgcct gcttttttct ggcgtgtata 262861 gtctttcagc gccgtaaaaa cgacctttga tagtaagaaa atcgcgatta aattcacgat 262921 gaccatcaaa cccatgaaca aatcagcaag atcccagacg agctggactt tggcaacaca 262981 gccaaacacg atcattgcca gcacgccgat acggtagaca aaaatcagtt ttttgctttt 263041 gttcaaaaag ccgatattgg tttcgccata ataatagttt ccaattagag cacagaatcc 263101 gaataacaaa atcagaatcg cgagaaagcc tgatgcccat gatccgacat gggagctgag 263161 ggaggcttgt gtcaaggcga ttccgctcag acccggagta tgataggcat ccgaaaacag 263221 aatgataaaa gcggtgcttg tacaaatgac cagtgtatct gtcagtacac caaaagcttg 263281 gatcagcccc tgtttgacgg gatggcttgt tgtggcggtg gcagcggcat ttggtgcgct 263341 tcccattccc gcttcgtttg aaaagattcc ccgtctgacg ccttgcatga gtgccgcgcc 263401 caaagccccg ccggcggcct ggtcaaaacc aaacgcattt ttcacgatta gcgcaagcac 263461 acctggcagc tgcgtaatgt tggagaaaat gacgaaaaac gcaactccga tatacaggac 263521 agccaatacg acgacaatgg attcagccag ctttgcaatg cgcttgactc cgccaaaaat 263581 aatcgtgccg aatacagcaa ttaaaatgag tcccaatgtc aggcggtttg tgccaaacgc 263641 gttttcaaag gcaaggctga ctgtattgga ttgaaccgag ttgaagacga taccgaacga 263701 taaggtgatt aacacagcga acagcgcgcc catccacctt ttgttcagcc ctttttccat 263761 gtaatacgcc ggcccgccgc ggaagccgtt tacatctttt actttataaa tctgagccag 263821 tgtgctttcc acaaagctgg atgctgatcc gataatggcg ataatccaca tccagaagat 263881 tgcaccgggc ccgccgagtg caatggcgat agcaatgccc gtaatatttc ccgttccgac 263941 acgggccgcc atgctgatgc aaaaggcttg aaacggagaa atgctgtttt ttgaccggga 264001 agcagcacct tctcttaata ccctgaccat ttctttcagc atgcgaacct gtaaaaactt 264061 aagcctgaac gtaaaataga ttccaaaaga aaggagcaaa acaattaata gctttgacca 264121 caaaagatca tttgcaatac cgacgatatg ttctaggatt tgctgcatag aatcacctct 264181 tttttcatgt ttaaaaaatg ctgagctccc attcctgcgc catatgcttc agcagcatac 264241 cgccagtgag gctgttgccg tattcatcaa tggcaggccc gtaaatgccg atgccgcatc 264301 cggattgaaa aggctgttct cttctggcgc ttggaggcac cagcgccatg atgccgccgg 264361 agacgccgct tttggccggc acgccgacaa acgccgcata tttgcctgaa gcgttgtaca 264421 tgccgcacgt cagcattaat gccttggcca attttgccac atcttttgga atcacctgct 264481 cgtgtcgaat cggatgatac ccgtcatgag caaggatcag gccgatcaac gcaatatctt 264541 ctgtagtgct ctccatagcg cattgcttca agtacacctc aagtgtttct tctacttcag 264601 cttctaaaaa gtttgtttct tttaaatagt aggccagcgc tctgttgcgg tgggcggttt 264661 cccattcaga acggaatact tcttcatgaa ttcttggccg ttttcctatc aaagtttcca 264721 tcaccgagta aagaaactcg agcttttcgt atgcagattc tccgggaagg atcgaagcga 264781 tggtgagggc acccgcgttg atcatgggat tgaagggctt tcccggcttg ttgatttcga 264841 gccgaatgat tgaattaaag gcgtcacctg tcggctcgac atctacgcgg tcaagcacat 264901 agggaatgcc gcggctcatg caggcggcaa taaagctaat cacttttgaa atgctttgca 264961 tggtaaaaga gacgttccag tcgccggcgt gtatcatcgt tccatcaggc tccaatacac 265021 agatgccgag ctgtgaatca ttgacttttc ctaaagcggg gatatagttt gcgctttgtc 265081 cattggcggc aaaagggcga tagtattcaa cccaatcatg aagctgtaac gccgggttta 265141 tgtctttctg gtgctctttt atcaattctt tcatcgaatt cctcctcact gatttttttc 265201 ttaaaggact gaggtgtatc aaaacgaagg ctaagggggc gttaaacgct ttcataatag 265261 cggaaggtat aattactgta taatggagac tacagaatca tacaaaatac gacaaaaaca 265321 ttttgaaaat aagcagtaag atttataaaa acctcatgtt ctgggtcaaa agcaatttgc 265381 aggttttctc ccgattcccc aaaataaaaa gcgaggatgt gatcaacata aaactggaac 265441 ggtttattga aaaagacgga tatatactgg ccctcatgct gattacggtg ccgctggccg 265501 gtgaactgaa attttatccc ctcaatgaag aattccgggt cagctttggg gcaccggttt 265561 ttttcttctt tttatcattg ttgcggcatg tgcccgctgt gctgccgggt tttctgactg 265621 gagcggctgt tttcatcttt cgcgtctttc tggaattatg gggcggagga cacaatgggc 265681 tgactccgat tctgtatgat caagcgtctg gctttttctt ttatatgact tacgcctgtc 265741 tgttttccat attaaaggcc aatcgtttcc gtgaacggcc gattatgctc ggtttcattg 265801 ggtttatgat tgaagttgtg tcagattgtg tcgagctaac tgtgcaattt ctcatttttc 265861 atacggttgt cacgcctgag aaaatcactg acattgcggt gattgcgatt tctcacacat 265921 ttattgtgat gagcttttat agtgtgctga agctgtatga aacacaatcg agagaaaaac 265981 agacaaggca gcagcacgag cacatgctga tgatcgtttc caatttatat gaagaaacgg 266041 tgcacctaaa aaagacattg aaaacgacag agaaagtgac aaacgattcg tatcagctct 266101 atcgggaaat gaagggcaag gatgttcagc tgagcggcag aatcctgaga ctggccggag 266161 agattcatga agtgaaaaag gacaaccagc ggatattcgc agggctttca aaactgattt 266221 cgaatgagag tttgagagat tatatgaggg cttctgattt gctgcagctc gtgattcgaa 266281 tgaatgaaaa gtacgctgaa gcactaggga agcagattga tttttactgc tcgatcgagg 266341 gagagcatga cgaatatcac gtatttatcg tgctttcgat cattaataat ctaacagcaa 266401 atgcggtaga ggctatggat gaagagggaa tggtcagcct gaggctccgt aagccaaatg 266461 agagtatggt agaattccag gtggaagaca atggccccgg gatttccgag aaaatcggag 266521 acattgtgtt tgacccgggc tttacttcaa aatatgacga atttggcacg ccttctacgg 266581 gtatcggact ttcctacgta aaggaaatcg tgacagagct agaaggggat atcacgtttg 266641 ataatcagca gcggggagtg gtgtttgcca tcaggctgcc tgtccggcat ttgattcaga 266701 aagggtgaac caaaagctat gcgttttttt attgcagatg atgaccgtgc ggtgcggtca 266761 attttaaggc agatcattga ggacgaagat ctcggggaag ctgctggtga agcagacgac 266821 ggaagccaag tggaagggca tatgctgcaa tttaagcaga ttgatatttt attaatcgat 266881 ctgttaatgc ccggaagaga cggcattgag acgattcgtc agatccagaa tacgtactcc 266941 ggcaaaatcg taatgatctc tcaagtggag gcgaaggaaa tggtcgggga agcgtactcg 267001 ctcggcatcg aatattttat ccataagccg attaaccgca ttgaaattgt cacggttctc 267061 caaaaggtga aggagcggat cgagcttgaa cactcgattg gagccattca gcattctcta 267121 agccggcttg tcaatcggac tgaacggaaa gcgcgtcccc agcagaagag tgacagcggt 267181 ttaaaagagg caggaacatt cctgttgtcc gagctgggca tgatgggaga aggcggcgca 267241 catgatctca tggcggtcct gcagtattta gcagaacacg agcaatccga gccgcacgaa 267301 aaacaaagcc cttcgctaaa acaaatattc acccaagtag cggtacggaa gctggggaca 267361 ggagcctcac agacggaagt caatcgcgaa atgaaagcct cggagcagcg tatccgcaga 267421 gcgattattc attcgctgca ccattttgct tcactgggca caactgattt ttcgaatcca 267481 aaatttgaaa cctatgcatc gaaattcttt gattttccgg ttgtcagcca gaaaatgaaa 267541 gaactccaat ccaaggatgc aaaacccctt gcacctgcta gaataaatat gaaaaaattc 267601 atccacgtgt tttttttgga agcaaagctt ttgcatgaga cgatgaaaca aagaaggata 267661 taaaccaaac agccggctga ccaggctgtt tttttgctgc gcagaatccc ggccggacag 267721 tgatttaccg cttttttata aaatatcaga aaataaagat attgacttat tgtttatttg 267781 tcttacaatt aaacaaaagg atatatggga aggagcggat gtgaaagaaa aattaataaa 267841 agcgcttaca gatagaggcc gtatacacaa ataacaggag gttatgttga tgagccgtat 267901 cagaaaagca cccgctggaa ttttaggttt tccggttgct ccttttaaca cacaaggaaa 267961 actggaggaa gaagctcttt ttcaaaacat tgagtttttg ctgaatgagg gcttggaagc 268021 gatatttatc gcttgcgggt ctggtgaatt ccaatctctc agccagaagg aatatgagca 268081 aatggtggaa gtcgcagtct cggcagccgg aggaaaggtg ccggtctaca cgggggtggg 268141 cggcaacctc agcacagcgc ttgattgggc gcagctgtcg gagaaaaaag gcgccgacgg 268201 ctacttgatt ctgcctccgt atttggtgca tggcgaacag gaggggctgt accagtatgc 268261 gaaaacgatt attgaaagca ctgacttgaa cgcgattctt tatcagcgcg ataacgcagt 268321 tctctctgtt gaacagatca aacgtctgac cgaatgtgaa cagcttgtcg gtgtcaaaga 268381 cggggtagga aatatggatt tgaatatcaa tctcgtctat acgatcggcg accgcttggg 268441 atggctcaac ggaatgccga tggctgaagt gacgatgccg gcttatctgc cgatcgggtt 268501 ccactcttac tcttcagcga tttcaaatta tatcccgcat atttcgcgaa tgttctatga 268561 tgcattgaaa aacggaaatg acgagcttgt gaaggaactc tatcggcatg tgattctgcc 268621 gatcaacgac attcgcaaac aacgaaaagg ctacgccgta tccttgatta aagccggtat 268681 ggaaatcatg ggtttgaatg taaggaatac agccagaccg cctgtcggcc cggttgaaaa 268741 agatcattat cagcaattgg aagcaatttt gaagcaggcg gctgaccgtt ttccgaaaaa 268801 agccgcgacg gtttgaccag aaaaaacacg aaaggggcaa tgggcatgtc tgtgatcacg 268861 gaacaaaaca cgtacctcaa ctttattaac ggagagtggg ttaagtctca atcaggcgat 268921 atggtcaaag tcgaaaaccc tgccgatgtg aatgatattg tcggatatgt acagaattca 268981 acggctgaag atgtggaacg tgccgtcacc gccgccaatg aagccaaaac ggcttggaga 269041 aagctgacgg gtgccgagcg cggccaatac ttatacaaaa cagcggatat catggagcag 269101 cgcttggagg aaatcgccgc ctgtgcaacg cgtgaaatgg gtaaaacatt gccggaagcg 269161 aagggagaaa cagcccgggg gattgccatt ctgcgctatt acgccggaga gggcatgcga 269221 aaaacgggtg acgtcattcc gtctactgac aaagacgcgc tcatgtttac cacccgtgtt 269281 ccgctcggtg tggtcggtgt gatttctccg tggaacttcc cagtggcgat tccgatttgg 269341 aaaatggcgc cggcattggt atacggcaat accgttgtca tcaaaccggc gacagaaaca 269401 gctgtgacat gcgcgaagat cattgcctgc tttgaggaag cggggctccc ggcaggggtc 269461 atcaatttgg tgacaggccc gggttctgtt gtcgggcagg ggcttgctga gcatgacggt 269521 gtaaacgccg ttacgtttac cggttcaaat caagtcggaa aaatcatcgg gcaagccgct 269581 ttagcgaggg gagccaaata tcagcttgag atgggcggca aaaaccctgt catcgtagct 269641 gatgacgctg accttgaagc tgcggcagaa gctgtcataa cgggggcctt ccgttcaacc 269701 ggccagaaat gcaccgcgac aagccgtgtc atcgtacaaa gcggaattta cgagcgcttt 269761 aaagaaaaac tgctccagcg cacaaaagat attacaatcg gagacagctt aaaagaggat 269821 gtctggatgg gaccgatagc cagcaagaat cagcttgata actgcctgtc atacattgag 269881 aaaggcaaac aggagggcgc ttccctttta ataggaggag aaaagctgga gaacggaaag 269941 tatcaaaacg gctattatgt tcagcctgcc atctttgaca atgtgacatc tgagatgaca 270001 attgcccagg aggaaatttt cggtccggtg atcgccttga tcaaggtgga ctcgatagag 270061 gaggcgctga acatcgccaa tgatgtgaag ttcggtttaa gtgcatccat cttcacggaa 270121 aacatcggcc gaatgctttc tttcattgat gaaatcgatg ccgggctggt tcggatcaat 270181 gcagaaagcg caggtgttga gctgcaggcg ccttttggcg gcatgaagca gtcgagctcc 270241 cactcccgag aacagggtga ggcagcgaag gactttttca cagcgatcaa aactgttttt 270301 gtgaagccgt aatggtgctg gaaagaggcg tgcgtctctt tcccggttta tcacaaccag 270361 catatgattc tctactttga aaaggagaag atactatgaa aaaagacttt gcgagtgtta 270421 ctccggcggg caaaaaaacg tccgtgcgct ggttcatcgt gtttatgctg tttcttgtga 270481 cctctattaa ctacgcggat cgagcgacgc tttccatcac cggagattcc gtccagcacg 270541 atttgggatt ggactcggtc gccatgggat atgtcttttc tgcctttggc tgggcctatg 270601 tcatcggaca gcttccgggc ggctggctgc tggaccgttt tggttcaaag actatcattg 270661 cgttaagcat ctttttctgg tcgtttttta cgttgctgca aggggcgatt ggctttttct 270721 ccgccggcac agcgattatc ctgctgtttg cactgcgttt tctggttggt ttatcagaag 270781 cgccttcatt tcccggaaac ggcagagttg ttgcctcatg gtttccaagc tccgagcgcg 270841 ggacagcttc agcctttttt aattcagcac aatacttcgc aatcgtcatt ttttctcctt 270901 taatgggctg gcttacccac tctttcggct ggcattccgt tttcgttgtc atgggtattg 270961 caggcattct tctggctgtc atctggctaa aaacggtgta tgaaccgaaa aaacatccga 271021 aggttaatga agctgagctt gcgtacatcg aacagggcgg cgggctgatt tccatggatg 271081 acagtaaaag caaacaagaa acagaatcga aatggccgta tatcaaacag ctgttaacga 271141 accgcatgct gattggcgtg tacatcgcgc aatactgtat tacgactctc acctatttct 271201 ttctcacatg gtttccggta tatttggttc aggcccgcgg catgtctatt cttgaagctg 271261 ggtttgtcgc ttccctgccg gcgctgtgcg gatttgccgg cggcgtgctt gggggcattg 271321 tgtcagacat cttactcaaa aaaggccgtt cactgacctt tgcaagaaaa gtgccaatca 271381 ttgccggcat gctgctgtct tgcagtatga ttgtctgtaa ctacacagat tcagcatggc 271441 tcgtcgttgt cattatgtcg ctcgcgtttt tcggaaaagg cttcggcgca ttgggttggg 271501 ctgtcgtgtc ggacacgtct ccgaaagaat gtgcaggatt aagcggcggt ttgttcaaca 271561 ctttcgggaa tattgcctca attacaacac cgattattat cggatacatt gtcaatgcca 271621 ctggatcttt caatggcgcg cttgtgtttg tcggcgctaa cgcgattgcg gcgatcctca 271681 gctatttgct gctggtcggg ccgatcaaac gggtcgtgtt aaagaaacaa gaacaagacc 271741 ccgatcaatc gttgcctgtc taatatttat gaaagcgctt tataaaggga ggaaaatgca 271801 tgagttcacc gatacaagag caggttcaaa aagaaaaaag atcgaatatt ccctcaattt 271861 ctgaaatgaa ggtgattcct gttgcgggac atgacagcat gctgctgaat ctaagcggag 271921 cacacagccc gttttttacc cggaatatcg taatcttaac agacagcagc ggaaatcagg 271981 gagtcggcga ggtgcctggc ggagagcata ttcgccgcac actggagctg tcagagccgc 272041 ttgttgtcgg aaaatctatc ggtgcgtacc aggcgatatt gcaaacggtc agaaagcagt 272101 ttggcgatca ggacagggga gggcgaggaa accagacgtt tgatttgcgc accactgtgc 272161 acgccgtcac cgcactggaa gcggctttgt tggatttgct tggaaagttt cttcaggaac 272221 cggtcgcggc tttgctgggc gaagggaagc agcgtgatga agtaaaaatg ctcggttacc 272281 tcttttacat cggcgaccga aatcggacga ccttgccgta tcaaagcgat gagcagtcag 272341 attgtgcgtg gttccgtctg cgccatgagg aagcgctgac gccggaggcc attgtgcgtc 272401 ttgccgaatc cgcacaggag cgctatggct ttcaggattt caaattgaaa ggcggggtgc 272461 tgcggggaga agaggaaatc gaagctgtta ccgcattatc gaaacgtttt ccagaggcaa 272521 ggatcactct tgatccgaac ggggcatggt cattagagga agctattgca ttatgcaaag 272581 gaaagcaaga tgtgctcgcg tatgcggaag atccatgcgg ggatgagaat ggctactccg 272641 ctcgtgaagt aatggctgaa ttccgccgcg cgacagggct tccgactgcg acaaatatga 272701 ttgcgactga ctggcgggaa atgggtcacg cgattcagct ccacgcggtc gatataccgc 272761 tggctgatcc gcatttttgg acgatgcaag ggtcggtgcg ggttgcgcaa atgtgccatg 272821 attggggttt gacatggggc tcgcactcca acaaccactt tgatatttcc cttgcgatgt 272881 ttacccatgt ggcagcagcg gctccggggc ggatcacggc gattgatacc cattggatct 272941 ggcaggacgg gcagcgatta acgaaacagc cttttgagat ttcttctggc tgtgtcaagg 273001 tgccggataa gcctggacta ggcgtcgata ttgatatgga acaagtggaa aaagcgcatg 273061 agatctatcg gaaaatgaat ttaggcgcac ggaatgatgc gatcccaatg cagttcctga 273121 tcagcaactg ggaatttgac cggaagcgcc cgtgtcttgt gcgataagtt tgattgtaaa 273181 tattgtcata tccgctattt tgtcttacaa ttgaacaact gaagggagag ttgttcgtgt 273241 acgaaggttt agaggatttg aaagtcgata cagtcaatcg gaaaacatta gccaagcagg 273301 tcatcgaacg gattgtccat ttattatcga gcggacagtt gagggccgga gacaaattgc 273361 cgacagaaat ggaactgatg gacattttgc atgtcagcag gccggtgcta cgggaagcac 273421 tcagttcact tgaaacgctg ggcgtcatta cgagaaaaac acgagggggc acatatttca 273481 acgataaaat cggcatgcag ccattttccg tcatgcttgc tttggccact gataatcttc 273541 cggctatcat tgaagcgcgg atggcgctag aactcgggct cgtgacaatt gccgcggaaa 273601 aaatcaatga ggaagagctt cagcgtttgc agaagacgat cgacgatatt gccaacagca 273661 ctgacaatca ttatggtgaa gcggataaag agttccatcg aattattgcg ttaagcgcca 273721 ataaccccgt cgttgaaggg atgattcagt ccctgctgat cacccatgcg aaaattgaca 273781 gccaaattcc gtacagggag agagatgtaa cggtcgaata tcacaaaaaa atctacgacg 273841 cccttgccaa aagagatccg tacaaagcac attaccacat gtatgagcat ctgaaatttg 273901 tccgtgacaa aattctaaaa ggaatggatg aaaaataatg gtgagcaacc gcagttgaaa 273961 cgtaagagct gcggtttttt taaaccaatt tagaaaacgc ttactaaaat atgaggagtg 274021 attttcatat ggcgatgaac ctcaggaaga accaagcccc cctttacatc aaagtgcatg 274081 aaatagataa caccgcgatt attgtaaatg atggagggct gccaaagggc actgttttct 274141 catgcgggct cgtacttgaa gaggatgttc ctcaaggcca taaggtggcc ctcaccgatc 274201 tcaatcaagg ggacgagatc gtgcgttacg gagaggtgat cggatttgct gatgagacga 274261 tcaaacgcgg gagctggata cgggaagccc tcgtgagaat gcccgctcct ccggcgttag 274321 acgatcttcc tctcgcaaac agggtgccgc agccgcggcc cccacttgaa ggatatacat 274381 ttgaaggata ccgaaatgcg gatggcagtg cggggacaaa aaatatcctc ggcatcacga 274441 caagtgttca atgtgttgtt ggcgttttgg attatgcagt caaacgaata aaagaagagc 274501 tgctgccgaa atacccaaat gtcgatgacg ttgtgccgct gcatcatcaa tacggatgcg 274561 gcgtggcgat caatgcgccc gacgctgtca ttccgatccg cacgattcaa aatcttgcga 274621 agcatccgaa cttcggcggt gaagtaatgg taatcggatt gggatgtgaa aagctcctcc 274681 cggaaagaat tgcctccgaa aatgatgatg acattctatc gctccaggat caccgaggtt 274741 ttgcggcgat gatccaatcc attttggaaa tggcggagga acggttaatc aggctgaaca 274801 gcagaacccg ggtgtcatgc cctgtttcgg atctggttat cggcctgcaa tgcggcggca 274861 gtgatgcgtt ttccggcgtg acggcgaacc ctgccgtggg gtatgcggct gatttattgg 274921 ttcgcgcagg tgcaacggtt ttgttttctg aagtgacaga ggtgcgggat gccattcatt 274981 tattaacgcc gcgggctgtc agtgaagagg tcggacaatc gctgatcaaa gagatgaagt 275041 ggtatgacag ctatcttcgg cggggagacg cagaccgtag cgcaaacccg tcaccaggca 275101 ataaaaaagg cggattatcc aatgtggtgg aaaaagcgtt aggttcggta gcgaaatcag 275161 gcacaagccc catctccggc gtgctcggcc ctggtgaaag agcaaagcaa aaaggcctgc 275221 tgttcgcggc gacaccggca agcgattttg tgtgcggcac cctgcagctg gctgcgggca 275281 tgaatttgca ggtgtttacg acagggagag gaacaccata tggcctggct gctgcgccgg 275341 ttctgaaagt atcgacgcgg cattccttat cagagcattg ggctgattta atcgatatca 275401 atgccggccg aatcgcgaca ggagaggcca gtatcgaaga cgtaggctgg gaaatcttca 275461 ggacgatttt ggatgtggca agcggccgca aacaaacgtg ggcagaccgt tggggtcttc 275521 ataatgattt gtgcttgttt aatcctgctc cagtgacttg attcatgttt ttatagcgga 275581 aagatggaat atgctgtaaa atgaaaatca gcgtatagga aacggagggg ttacagcatg 275641 gcattcatta gattccgagt gacacgaatt caatagtgaa caactctcgc ctgaatgcga 275701 gagaatcggg atgaatccgc ctatgtatga gcccttatat ggttatcaaa aaagagggtg 275761 gcgtgcctgc ccttttttgt gccttcaagc atcccttctc tctactgcag gccggagcat 275821 gagaaagggg aaatgggatg acaaacctta acgaaaaaca gcttatcact gagattgtcg 275881 ggcttgcacg cagccaaggt ttgacggttc attctgagaa cgcgcaattg aatgaaaccg 275941 gaatggactt tcaagttgta tttgccaagg acgacacagg tatgccatgg gtgctgcgaa 276001 aaccgcggcg aagtgatgtt gtggaaagag catctgcaga aggcataacg cttgcctttc 276061 tccgcgcgaa tctgactgct gatgtgccgg attggagaat tcatacaccg gaattgatcg 276121 cttaccccat gttaaaagga acgccggctg ctggaattga cttggaacaa aagcaatatg 276181 tatggaatat ggatcatcag ccgccgtcag acgactttgt ccgcacactt gccgacatac 276241 tggctgaatt acatggcacg gatcaaatat ctgctgggca atccggaata gaagtgataa 276301 ggccagaaga tttcaggcaa atgacagcag actctatggt tgatgtgaag aataagcttg 276361 gcgtatctac gacgctttgg gaaagatggc aaaagtgggt agatgatgat gcatactggc 276421 cgggtttctc ttctttgata cacggcgatc tccacccgcc gcatatcctt atcgatcaaa 276481 atggacgtgt cacaggactt ctggattgga cagaagcgaa ggttgctgac ccagccaagg 276541 attttgttct ttatcaaacc attttcggag aaaaagaaac tgcccgtttg cttgaatact 276601 atgatcaagc aggcggccga atatgggcaa aaatgcagga acacatctca gagatgcagg 276661 cggcgtatcc ggtggaaatc gccaagctag ctctgcaaac acagcaggag gaacacatca 276721 atatggcgct ggaagcactt ggtgtaacat cggattaaga attgacttcg tttcatgaac 276781 cgagtattat aaactctaca aataatagaa cggattaaca atcgtgagga agagcaagta 276841 cgcatcagaa tggaggttca gagagtcggt ggcaggtgtg aaccgatcct cccctgatgc 276901 cgaatgggct tctgaattgc tttgctgaac ggatagtagg cgatgccggg tttctctccc 276961 cgttaccaag agaggagtat cgaaacatag gttttctgta cttagagtga acggctgtat 277021 agctgttaat aaaggtggta ccgcgagacc ctcgtccttt gcataggacg ggggtttttt 277081 gtgtttctta aaggaggtga cggccaatgt acgatggctg gtggtggcat agcagatgag 277141 ttagaaagga ggatatcaaa tggtcattgc aactgatgat cttgaggtcg catgtcctaa 277201 atgtgaaaga gcgggagaaa tcgaaggaac accttgcccg gcctgcagcg gaaaaggtgt 277261 tattctgact gctcaaggat atacgcttct cgattttatc caaaagcatt tgaataagta 277321 aaggagaaaa gctgagctga gatgagagca gaagagcaga gtaagattcg tgaggccgca 277381 gcaggtacga tttttttgct gatcggaaca gtttgttttg cgtctaaatc gatttggata 277441 aaatgggcat accaaatggg tgctgagcca gatgccgtgc tgctatacag gcagctgctg 277501 gctgttccgc tgttttggct gattttttta atataccgtc ctccaatgcc agacggtaag 277561 aaaaaaggag acctatggaa ggcttgtggc gcgggagtgt tttgtttttt tctgtctccc 277621 ttgcttgatt ttatcgggct gaaccatgta tccgcaatgg ttgaacgtat attgctgatg 277681 agctatccgt tgtttgtgtt tggattcacc gcgtgtcgtg accggaaaat gtcctcaatt 277741 caggaccttt tcgcagttct ggcggtcatg tttgggcttt tcttggcgct gggcggctgg 277801 aatgctgagc ttttccaggc gaatatgatt ggagctgtat tcattttgtt atcttcggcc 277861 gtctatgctg gttatcttgt cctttccggg catctcgtcc atcaaatcgg agggatccgt 277921 ctcaatgcat acgggatgac agctgctgga gctgccatga tgctttacac agggataaaa 277981 tcggcggctg gcatgaatac gccaatggca gcatatccgc tttctatgta tggtttgttc 278041 gcagtaattg cagtcgttac cacagtgatt ccatttgtgc taatgcttga gggcataaaa 278101 cgaatcgggg cacagcgagc cgccgccatt tcaatggcag ggcctatcct gacgattttc 278161 tatggagctt tatttctcgg tgaacggctc gggctcattc aagtcattgg atgcggtggc 278221 gtattttttg tcattacggg catggaatac aggaagctga aaacaggaaa aaaagaataa 278281 tttttataaa acacacacgt ttttcaatta caataagtgt aattacgtgt gtgttttttg 278341 attttgtaaa ggttaggtga ggagatgcag cgcatattgc ttgtagaaga cgaccactca 278401 atcagtgaaa tggtggatca ttatttaaca aaagaaggct ttggaattgt gcatgctttc 278461 gacggagaag agggcatccg gctgtttcag cagggttcat acgatttggt cctccttgat 278521 atcatgctcc cgaagctgaa cggcatggat tttctgaaaa tcatccggga aaaaagcaat 278581 ataccggtct taatgatttc ggcaaaagat ggagatgtgg acaaggcatt gggactgggc 278641 tttggggcgg atgattatat cgccaaaccg ttttcgatga ttgagctgac agcccgagta 278701 aaagccgcga tacggcgggc gacgcaatat tcggcagagg agccggctgt gaataaggtg 278761 atccggattc accagcttgc gatagatata gacaatgttt ccgttttgaa aaacggagag 278821 ccgctccagc tgacgtcaac agaatggcag ctgctgtgct tatttgcatc aaatcctaaa 278881 aaagtgttta cgaaagaaca aatctaccgt tccgtttgga atgaagagta ctttgatgat 278941 cagaacatca ttaacgtaca tatgcggcgg ctcagagaaa agattgagga tgacccctcc 279001 tcccctcaat atattaaaac gttatggggc atcggttata aattaggaga gttttagaat 279061 gacagtgcta tgggtggccg ctgtcatcgc tctggcgtgt ctgaatgtga ttcaattcat 279121 aatgaaaaag aagcgggacg ggaatctggc ttacacggct gaccagctta gctacatgct 279181 cagccgggat tcggcaggac aaattttgct tcctacagac gatcatgcgc tcaaagactt 279241 gcttgttaac atcaatctta tcgttgagaa tcgtcagcag atcagcgccc aatttgccaa 279301 aacagagcaa tccatgaagc ggatgctgac caatatgtcg cacgacctga aaacgccgtt 279361 aacggtcatt ctcggttata ttgaagccat tcaaagtgac ccgaacatgc cggacgaaga 279421 gcgggaaaga ttgctgggga agctccgcca gaaaacaaat gaacttattc agatgatcaa 279481 ttcctttttt gatttagcga aattagaatc tgaagataaa gagatcccga tcaccaaagt 279541 acatatgaac gacatatgca aacgaaatat cctgcactat tatgacgctg ttcagtcaaa 279601 aggctttcaa gcagccatcg atatccccga tacgccggtg tatgcgcagg cgaatgaaga 279661 ggctctggac agaatcctgc aaaacctatt gtccaatgcg attcaatatg gcgcggccgg 279721 caagttaatc gggctgacgc tgtcttatga tgagaggaac atcgccatca ccgtatggga 279781 tcgcggaaaa gggattagtg aaaccgatca gcagcgggtg tttgagaggc tgtacacact 279841 ggaagaatcc agaaataaag catttcaagg aagcggcttg ggtttaacca tcacaaaacg 279901 gcttacagaa aaaatgggag gcatcatatc cgtccaaagc aagccgtacg aacggactgc 279961 atttacgatc acattgaaac gcatgacata ttaatcgtaa gaatttctta aggtttgaga 280021 aataaaaatg acagggctcg ccgctacaat agaaaacagg aaaagagagg gaaggagaaa 280081 caaagttgac ttatatcgta caaacaaacg ggctgaccaa aacatatcag ggcaaagagg 280141 tcgtatccaa tgtcagcatg catattaaaa aaggtgaaat ctatggcttt ctcggcccga 280201 acggcgcggg gaaaacaacc attatgaaaa tgctgacgag ccttgtcaaa ccgacaagcg 280261 gtgaaatcat catccttggg aacaagttca cccacacgtc atatgaggtg ctggggaaca 280321 tcggcagcat gattgaatat ccgatttttt atgaaaacct gacagctgaa gaaaatttag 280381 atctgcattg tgaatatatg ggataccaca ataaaaaagc catacaagaa gtgctggata 280441 tggtgaattt aaaacaaatc gacaaaaaac ccgtcaaaac cttttccctc gggatgaagc 280501 agcgccttgg aattgcgcgt gccatcctca cgaagccgga cctgcttatt ctggatgagc 280561 cggtgaatgg tcttgaccct ctcggcatta aaaagatcag gcaattgttt caagtgctga 280621 gcaaagagta cgggatgacg ctgctgatct caagccacct gctgggtgaa atcgaacaaa 280681 tcgcggacac aatcggcgtc attcgggacg gcaggctgct tgaagaggta tcaatggagg 280741 atgtcagggg ccagaacact gaatacatcg agcttgtcac gccgaatcag acaagggcct 280801 gctttgtgct ggagaaagag ctgcaattaa ccaactttaa aatattaaat gagaaaacga 280861 ttcgaattta cgaggctgaa gcctctcagg ctgccatatc caaagcattg attttaaatg 280921 atgtagacat tgaatcaatg aacaaaaagt atacgtcgct ggaggattat tttatcaaat 280981 tgatcaacgg caatagcatc agtgcgtaaa ggaggagaga cacgttgatg aatttgatca 281041 gaatcgaatt aagaaaaatg aaaatgggct ggtatatcag aggtgccctc attgccaacg 281101 tgatcattat gggttttatg tggctgatca gttattccga aaaagccgat ggcggggttt 281161 cgttccaaag tacggatgaa gcattcctca tcatcggcac cttcgtcaga gcggtattta 281221 tcgtatttgg cgctgtgctg atcgtaaaat tggtgatttc ggaatataaa aacaaaacca 281281 ttcttgtgat gttcacgtac ccgatcagcc gtaaaaagct gctcaccgct aagctcatga 281341 tcgcgggcgg actgacgttt atcacgattt tactttcaaa tatactcata gccgccggtt 281401 tcttttggct gaactcgatc tgccatttca taccgggaga gcttacttcc gagatcattt 281461 ctcaacaggc ggtcaaaatg gcggttttcg cttttggcgc cgctggaacc agtttagttc 281521 ccatcttttt tgggatgcgt agacactcgg ttccggcgac catcatttca tctgtagtaa 281581 ttgtgatgct catcagctca acaagtccgg gcttctcgat ttcatctgtt gtgtatatcc 281641 cgttatcgtt agcggcattc ggtttgttct tttcctacat ggcgatcagg aatgcggaca 281701 agcaggatgc gtaaacaaag gcgcccaata tgtataaaag gccgatgctg tcagcaccgg 281761 cctttccatt atgagtctgt tcttgtttca agataatgct tcttgccaat ctctttgctc 281821 atcatataga aatggaagca atattcaccg attgccatga cgatcgcgcc gaataaagcc 281881 gccaatgcaa cttcaccgcc agtcatcccc atagaaagcg gcatgcccat cagccagatc 281941 acgagaaagg ccaaaccaaa atcagccaaa gttgcaatca tattattcca tttcggcaat 282001 acataaagat cgcccagcaa ataagaaata acccctaaca caatcgtcat tagcagcgta 282061 tcaccaaacg tgaaaccaaa gcccagacca agcaccagat acaacacaat aatcgtcata 282121 atacctttaa tagcgagcgc tttcacatgt gtcattacaa ttcctccttt tgtcatttga 282181 tttgttatgt ataattcctc aaatgtaaaa agttaaacct tatttctttt cggaggcggg 282241 tgcaaatctg ctggggagag gtcaatgatg tgaatccagg aattgaggct gcggcgcttc 282301 gacagcggaa acgtgaagct tgtactgcac cggacgctgc tttgatgccc aacagcccat 282361 tatgtttgct gtttttagat gaataaattt aaaaacttct cctgtccctc cgtcatcact 282421 tctgaagtaa tgaaatatga tgaaaagaga tcaaggggag gtgacgtgat ggcggtcgtg 282481 agagcaacga gtgcggatgt cgatttgatg gcaaggctgc tcagagcgga agcggaaggc 282541 gaaggcaagc aggggatgct gcttgtcggc aacgttggaa ttaatcggct gcgggcgaat 282601 tgctcagatt ttaaaggcct ccgcaccatc aggcagatga tttatcagcc acacgcgttt 282661 gaggctgtga ctcatggata tttttatcaa agggcgcgag atagcgagcg tgcccttgca 282721 cgccggtcga ttaatggtga aaggcgctgg cctgcaaaat ttagtttatg gtacttcagg 282781 ccgcaggggg actgtccagc ccagtggtat aaccagccgt ttgtggccag atttaagtca 282841 cactgctttt atcagccgac ggcggagacg tgtgaaaatg tatataacac attttagaga 282901 caggacaccg ttcaaattga acggtgtttt tctttgaaaa gatgcaatgc aaaatattcc 282961 tgtgagataa tcaaagaaaa aagagctgac ggagatgaca gaatggcaac aattgacctg 283021 caaaagaaaa gtgtaaagat cgtactggag aaaaagcagt taacgaaggt gacggctcgt 283081 gttggactgg ttcttgatat tacgggatcg atgagaccgc tctacaaaaa cgggacggtt 283141 caaaatgtgg tggagcggat tttggcagtg gctgatcagt ttgatgataa cggtttgctg 283201 gatgtatggg tgtatgataa tgaattttcc cgattaaagc cagtttcaga aaaggatttt 283261 tcgggctatg tcgatcgtga aattttaaat aatgaccgct tgcataaatt cggcagaaat 283321 gatgagccgc cagtcatgaa ggacgtgctg cgcaaatatg ttacggagga accgagctcg 283381 tatcctgctt tcattgtttt tatcaatgac gggggctgta aaaagtcaat caaaccgata 283441 attgaagctt cttctgataa accggtgttc tggcagtttg tcggcatcgg aaacggaaac 283501 tttgattttc tcaataaact ggatacgtta gaagggcgtg tcattgataa cacgaacttc 283561 ctgcatatcg aagagattga ccgcatttct gatgatgagc tttatgatgc tctgcttgct 283621 gaatttccat tttggctgaa agaagcgaag gaaaaaggga ttgtaagaga acaagagcct 283681 cctgctgaaa agccgaaaaa gaagggcttt ttcagcagat tgttttcgaa ataactgata 283741 aagagcactg agtcattctg cgaaatggct cggtgttttt gtttttttaa gatcatgtga 283801 agaaaaatag gccgaatggg cggcttgcaa acgacaggat atgcagaaaa cgcgtcattc 283861 agccagcttt cggcatgttt cagcagcagg cttgtgaggg aagacctgtt tttaatgttc 283921 agcgcttaca atcagttcac acttcttcac agtcgtttaa caatgatttc ctataatgga 283981 gacgatcaat gaggagagag gggatcttga atggcatacg acagtcgttt tgatgaatgg 284041 gtacagaaac tgaaagagga aagctttcaa aacaatacgt ttgaccgccg caaatttatt 284101 caaggagcgg ggaagattgc aggactttct cttggattaa cgattgccca gtcggttggg 284161 gcctttgaag taaatgctgc gcctaacttc tcaagctatc cgtttacatt aggggtagcg 284221 tcaggtgatc cgctttctga cagtgtcgtg ctttggacac gtctggcacc agatccgctg 284281 aatggcgggg gaatgccgaa gcaagcagtg cctgtcaaat gggaggtcgc aaaggatgag 284341 catttccgca aaatcgtaag aaaaggcact gaaatggcta aaccaagtct tgcccattcc 284401 gttcatgtgg aagcggacgg gcttgagcca aacaaagtgt actattaccg tttcaaaacc 284461 ggccatgaac taagccctgt cggaaaaaca aaaacactgc ctgcccctgg cgccaatgtg 284521 ccgcaaatga cctttgcatt tgcttcctgc cagcaatatg agcacggata ttatacggcc 284581 tacaagcata tggcaaagga aaagcttgat cttgtcttcc atctcggtga ttacatatat 284641 gaatacggcc caaatgaata tgtatcaaaa acaggcaatg tccgcacgca caacagcgcg 284701 gaaatcatta cgctgcaaga ctatcggaac cgtcacgctc aataccgttc tgacgccaat 284761 cttaaagctg cacatgcggc attcccttgg gttgtaactt gggatgacca tgaagttgaa 284821 aacaactatg ccaataaaat acctgaaaaa ggacagtcgg ttgaagcatt cgtgctccgc 284881 cgcgcggcag cataccaggc atactatgaa catatgccgc tccgcatttc ctctttgccg 284941 aatggcccag atatgcagct gtaccggcac tttacgtacg gaaacctggc gtccttcaat 285001 gtgcttgata cccgccagta cagggacgac caagccaata acgacggcaa taagccgcct 285061 tctgatgaat cgcgcaatcc gaatcggact ctgcttggaa aagaacagga gcagtggctc 285121 ttcaacaatt tgggcagctc gacagcccac tggaatgtgc tggcgcagca gattttcttt 285181 gccaagtgga atttcgggac aagcgcaagc ccgatctaca gcatggattc gtgggacggc 285241 tacccggctc agcgcgaacg ggttatcaat ttcattaaaa gcaaaaatct gaataatgtt 285301 gtcgtactga caggtgatgt acacgcaagc tgggcatcga atttgcatgt cgatttcgag 285361 aagacaagtt caaaaatatt cggagccgaa tttgttggaa cctcgatcac ttccggaggg 285421 aacggagcgg ataagcgagc ggatacggac caaattttaa aagaaaatcc gcacatccag 285481 ttctttaacg actatcgcgg atatgtccgc tgtacagtga cgcctcacca gtggaaagcc 285541 gattatcggg tgatgccatt tgtgaccgag ccgggcgcag ccatttccac gcgggcttca 285601 ttcgtttacc agaaagacca aaccgggttg agaaaggtat catccacaac aatccaaggc 285661 ggggtgaagc aatccgatga ggtcgaagag gatcgtttct tttcgcacaa caaagcccac 285721 gaaaaacaaa tgattaagaa gcgtgcaaaa atcacgaatt aaggagtgga aattatgttt 285781 tcaaacattg gaataccggg cttgattctc atcttcgtca tcgccctcat tatttttggc 285841 ccttccaagc tgccggaaat cgggcgtgcc gccggacgga cactgctgga atttaaaagc 285901 gccacaaaat cacttgtgtc tggtgatgaa aaagaagaga aatcagctga gctgacagcg 285961 gtaaagcagg acaaaaacgc gggctgaatg ctgatgaggc agacaccggg tctgcctctt 286021 tttttatgaa agggagggct tttttgaatg gataaaaaag aaacccatct gatcgggcat 286081 ttagaagagc ttcgccgccg gattatcgtc acccttgcgg cattttttct atttctcatc 286141 acggcttttt tgttcgtaca ggacatttat gactggctga tcagggattt ggatggaaag 286201 ctggctgtgc taggaccgag tgaaatcctc tgggtgtata tgatgctttc cggcatttgt 286261 gccattgcgg cttctatccc tgttgccgcg taccagctgt ggcgtttcgt tgcaccggcg 286321 ctgactaaaa cggagcgcaa ggtgacgctc atgtacatac caggtttatt tgcgttgttt 286381 ttggcgggca tctccttcgg atactttgtc ttgtttccga tcgtgctcag ctttttgact 286441 catttatcct ccggccactt tgaaacgatg tttacggctg accgctactt taggtttatg 286501 gtgaatttga gcctgccgtt cggcttcttg tttgagatgc ccttggtggt gatgttttta 286561 acaaggctgg gcatcttaaa tccttacaga ctggccaaag cgagaaagct ttcctatttt 286621 ctgctgattg tcgtgtccat attgattaca ccgcctgatt ttatttctga ttttctcgtg 286681 atgatcccgc ttcttgtcct gtttgaagtg agtgtcaccc tatcggcgtt tgtctacaaa 286741 aagaggatga gggaagaaac agcggcggcc gcttagtgca gcgtaccacc cggtgacttc 286801 acatcctcat catattgtgc ggccgtaaca gcggcgattc tcaatgcccg gacaatcgtg 286861 tccaggctga ggctcggcgc tgttttgtcg attgtttgct gcggaatgta aggaatatga 286921 ataaaaccgc cgcgaatgtg tggggatgtc cggctaatgt gatccattaa cccgtagaac 286981 aaatagttgc atacaaaggt ccccgctgtg taggaaaccg cagctggaat gccgtgttcc 287041 ttcatcttag cagtcattcg tttcacggga agccttgtcc agtaagcggc gggcccatct 287101 ggagaaatct cttcatcaat cggctgatgt ccttcgttat cggggattcg cgcatctgca 287161 aggttgattg ccactcgttc cggtgtaatc tgcatccgtc ctcctgcttg gccgacacaa 287221 attacgatat ctggctgatg tttttgaatg gcttggcgca gagtgtccag agcggatcta 287281 aagacggttg gaatttgttc cgctgtaata atggcttctt ctgtctcgaa gccattaagc 287341 cgtttcgccg cttcccatga tggattgacg gtttctttgt caaaagggtc aaagcctgtg 287401 atcagcactt tttttctcat tctcccatct cctttttctt ttattctatt gtttatttat 287461 gggtttttca tcaaaataat gtaaaggagt gaatcataat ggagcatttg ccggagcagt 287521 atcgccagtt attcccaacc ttgcagacgc atacgatgct tgccagctgt tctcagagcg 287581 cattggcaga gcctgtatca agggcgatcc aggattatta tgatagcctg ctgtataaag 287641 ggacgaactg gaaagaagcg attgaaaaaa cagagtttgc gagaaacgag tttgcaaagc 287701 tgatcggggc tgaaccggat gaagtggcga ttgtgccgtc agtttctgat gcactggttt 287761 ctgtagcatc gtccttaact gcatttggaa agaagcacgt tgtatataca gatatggatt 287821 ttccggcggt gcctcatgtt tggcaggcac actccgatta taccgtatcc gtcattccat 287881 caatagacgg cgtgctgccg cttgaacaat atgaaacgca tatttcggat gaaacagtac 287941 tgacgtgtgt tcctcacgtt cattatcgtg acggctatgt tcaggatata aaagcgattg 288001 ccgagatttc tcagagaaag ggctctttat tgtttgtaga tgcttatcaa tcagccgggc 288061 atattcccat tgatgtgaag gaatggggcg tagatatgct ggcagcaggc acccggaagt 288121 atttgctcgg cataccgggt gtggcgtttc tttatgtgag aaaggagctg gctgacgcac 288181 tgaagccgaa agcatcagct tggttcggaa gagagagcgg atttgatggg gcttatgcaa 288241 aagtcgcgcg ccgttttcaa acgggcaccc cagcttttat cagcgtatac gcagctgcag 288301 cggctttatc gctgctgaat catattgggg tttctcatat cagggatcat gtgaaaacga 288361 tctgtgccga tgcagttcaa tatgccgctg aaaaaggcct gcagctggcg gcggcacaag 288421 gtgggattca gccgggcatg gttgcgatcc gggatgagcg ggcatcggaa acggcggggt 288481 tgctgaagaa gaaaaaagtg atttgcgcgc cgcgggaaaa tgttatccgt ctcgctcccc 288541 atttttataa tacgaaggag gaaatgcggc acgcgattga tgaaatcgcg gcgaaaacga 288601 tccacaagta aacatgaaaa agcccctgaa cactagtcag gggcttttca tattaatgat 288661 ctactttaac gcgtttcata aagaaagcgc caattaaacc gataatggca acaatcattg 288721 caaacacaaa tgcgtgctgt acgcctgctg tcaaagcttg cgggatgact gccggatcgg 288781 cagggttttt aactgtactc atataatcat gctggcctgc agccataatg ctgaccgcaa 288841 ccgctgttcc gatagcgccg gccatttgct gcagcgtgtt cataatggcg gtgccgtctg 288901 gataaaattc acgcggcagt tggtttaaac cgtttgtctg tgcaggcatc atgatcatag 288961 aaatcccgat catcaagcag gtgtgcagga tgataatcag cacagctgtt gaagtggtcg 289021 tgacatttga gaagaaccat agtacaacgg tgacaatcac aaatcccgga atgacaagcc 289081 atttcggccc gtatttatcg aacaagcggc ctgtaacagg ggacataaat ccatttaaaa 289141 taccgcccgg caagagaaca agaccagatg caaatgcagt gaggactaag ccgccttgca 289201 gatacatcgg cagaagcagc atagatgaca gaatgaccat catacaaatg aacaccatga 289261 tcacacccaa aataaacatc gggtatttga acgcacggag gttcatcata ggctgcttca 289321 ttgtcagctg gcggattgaa aataagataa ggccgacaac gccgacaatc agcgacacga 289381 taacagtcgg gctggaccat cccccggagc cttcacccgc gttgctgaat ccgaatacaa 289441 tgccgccgaa gccaatcgtc gacaggatga tagacaatac atcgattttc ggctttgtcg 289501 tttcagatac attttgcata tatgcgatac cgaaaacaag cgccagcaca aggaatggaa 289561 gagagatcca gaaaatccag tgccagttga gatgctccag aaccaatcct gagaaagttg 289621 ggccgatggc gggcgcgaac ataatgacaa gcccgatcgt tcccattgcg gcaccccgtt 289681 tatgaggcgg gaaaatcacc aagattgtgt taaacatcag cggcagtaaa agaccggttc 289741 caagtgcctg aacgatcctt gccgctaata aaaacgagaa gctcggcgca agcgccgcaa 289801 tgaatgtacc taaaattgaa aagataagtg acacggtaaa aagctgtctt gttgtgaacc 289861 actgcaacag cagtcctgaa acaggaacaa ggataccgag tacaagcagg tagcccgtcg 289921 ttaaccattg gacggttgcc gctgtaatgt tcaattcctt cataaggtcg gttaacgcaa 289981 tattcagcgc tgtttcactg aacatgccga taaaaccggc caacagcaag gaaatcataa 290041 tcggcatcac tttgtattgc tgagatgctt tagctgttgt ttccaaaatc atttcccctc 290101 tctatcaact gcatgtagta tgtcgttttt tttatctctt cagcaggtca ggaatgcagc 290161 tggagatatg aaggagcggc gtactgtttt ttgccgtcaa agataaaagg atgccgcctt 290221 caatcatcgc gttaaccaca gtgctggctt cttttgcacg gctctcgctg cagccagtct 290281 gccgcagttt ttcctcatac acagaggccc attctttgta ggcttcatga caggcttcgc 290341 gcaacggttc gcttttcaat gacgtctcag ccgctagcaa gcccacaggc aagccttcaa 290401 tgtcttccgt acatgaaaac tggcaggaga gctccttcaa aaaggcttga atgccttccg 290461 ctggatcggt gcaggcttcc atgcagtccg cgattttctg acggatatac tccttcatct 290521 cattcacggc ttcgatcgca agctgttctt tacccccggg aaagtggtag taaagagagc 290581 ctttaggcgc gccgctttcc tttataatct ggttcagccc cgtgccgtaa tacccttgca 290641 gctgaaaaag ccgggtagct gccgaaagga ttttctcacg ggaatctcca taactcataa 290701 cattcccacc ttactgaatt gcaatcaaaa atatagtgac tggtctatta tcttgattca 290761 atcatcaatt gtcaagaaaa attcattgta tgaaaagaca aaaaaagaag gatatgacaa 290821 caaaaaatac tgagagaaaa gctgactgat cttttgactg aatagataaa atgtacaatg 290881 attaatcatc atatggatgt aaggagagaa atagatgaaa aaacaacgaa tgctcgtact 290941 ttttaccgca ctattgtttg tttttaccgg atgttcacat tctcctgaaa caaaagaatc 291001 cccgaaagaa aaagctcaga cacaaaaagt ctcttcggct tctgcctctg aaaaaaagga 291061 tctgccaaac attagaattt tagcgacagg aggcacgata gctggtgccg atcaatcgaa 291121 aacctcaaca actgaatata aagcaggtgt tgtcggcgtt gaatcactga tcgaggcagt 291181 tccagaaatg aaggacattg caaacgtcag cggcgagcag attgttaacg tcggcagcac 291241 aaatattgat aataaaatat tgctgaagct ggcgaaacgc atcaaccact tgctcgcttc 291301 agatgatgta gacggaatcg tcgtgactca tggaacagat acattggagg aaaccgctta 291361 ttttttgaat cttaccgtga aaagtgataa accggttgtt attgtcggtt cgatgagacc 291421 ttccacagcc atcagcgctg atgggccttc taacctgtac aatgcagtga aagtggcagg 291481 tgcccctgag gcaaaaggga aagggacgct tgttgttctt aacgaccgga ttgcctcagc 291541 ccgatatgtc accaaaacaa acacaactac aacagataca tttaaatcag aagaaatggg 291601 cttcgtcgga acaattgcag atgatatcta ttttaataat gagattaccc gtaagcatac 291661 gaaggacacg gatttctcgg tttctaatct tgatgagctg ccgcaggttg acattatcta 291721 tggataccaa aatgacggaa gctacctgtt tgacgctgct gtaaaagccg gagcaaaggg 291781 gattgtattt gccggttctg ggaacgggtc tttatctgat gcagccgaaa aaggggcgga 291841 cagcgcagtc aaaaaaggcg ttacagtggt gcgctctacc cgcacgggaa atggtgtcgt 291901 cacaccaaac caagactatg cggaaaagga cttgctggca tcgaactctt taaaccccca 291961 aaaagcacgg atgttgctga tgcttgcgct taccaaaaca aatgatcctc aaaaaatcca 292021 agcttatttc aatgagtatt gaagaaaaga aggcgaataa gccttctttt ttttggcttt 292081 ttaggaccaa taatgacctc tgaatcttaa aatttcttta aaaataagcc aaaattaccc 292141 tttacttaat taatttggta acgtaatata attggagaat ttgttacaaa aaaaggagga 292201 tattatgaaa tttgtaaaaa gaaggatcat tgcacttgta acaattttga tgctgtctgt 292261 tacatcgctg tttgcgttgc agccgtcagc aaaagccgct gaacacaatc cagtcgttat 292321 ggttcacggt attggagggg catcattcaa ttttgcggga attaagagct atctcgtatc 292381 tcagggctgg tcgcgggaca agctgtatgc agttgatttt tgggacaaga caggcacaaa 292441 ttataacaat ggaccggtat tatcacgatt tgtgcaaaag gttttagatg aaacgggtgc 292501 gaaaaaagtg gatattgtcg ctcacagcat ggggggcgcg aacacacttt actacataaa 292561 aaatctggac ggcggaaata aagttgcaaa cgtcgtgacg cttggcggcg cgaaccgttt 292621 gacgacaggc aaggcgcttc cgggaacaga tccaaatcaa aagattttat acacatccat 292681 ttacagcagt gccgatatga ttgtcatgaa ttacttatca agattagatg gtgctagaaa 292741 cgttcaaatc catggcgttg gacacatcgg ccttctgtac agcagccaag tcaacagcct 292801 gattaaagaa gggctgaacg gcgggggcca gaatacgaat taatgaaaaa caaaaccttg 292861 aagaatgcta ttcttcaagg ttattctgct ttcagcacaa tggttttcgc agccatatca 292921 tgaacggttt gttttttctt cgtaaatgcg gcagtcaaat agatcaggcg ggagaacaca 292981 tgcacccacg ctatcaggta acggacaatg gcttgcggga aggatatttt tttatatgtt 293041 tcgtccctca cgatttgcag cccgatgatt tttttgccca gtgtgccctt ccaatttgtc 293101 agcggcatca gcaaagggta cacaatcagc atcaatatgg cgacaataat gacaccggcg 293161 gacccatcgc caaacgtaaa tccggctgcc aaaatcactg ctgcggcaat gattacatca 293221 agtaaaagag cgcaggcgcg cagcatgaaa ccagctagtt ccaatagaaa cactccttaa 293281 aatgttaaat aaacacctaa tgattgtaaa aaagaagggc ctaaagtggg aataggtgat 293341 aagccttaaa tcacaaaagt tggtgaaaat gtcataggta aattggcata atcagccagc 293401 ttatcacatt accaaattct tttttagccc gaaaccaagc cctcagaagt tatttttgtt 293461 aaaatagaaa agttacaaca gaattcggag ggtttattgt gggaaaagtg aaacgaaatg 293521 ccccttgccc atgcggcagc ggcaagaaat ataaaaaatg ctgcggaagt aaagttgtcg 293581 acttcccggc ggaactagcg gcaaaagaag cgaaacaaat tcaggaagac ttagtggagt 293641 atgccttcac agtacataga gaaagcattt caggctttat caaccagcat gattttcttt 293701 ctgctatgga cagacagacg aaagacatca gcgtatttaa cttaggaatc tggggaatct 293761 tcttccaccc gcttgctggt gagaagacaa tcttcgaaga gtaccttcag aaaaaaggcg 293821 attcgatcac tcgtccgaaa acgcgtgaga tcgtagaatc atggcagagc atgacgcctg 293881 ctttattgct gctgaaggac ctgaaggaag gcatcattca ctttgaagat gtcattacgg 293941 caaaacaatt cgaagtggaa atggacgcca gcaatcaaga ccttcctcca gtgggaagcc 294001 tgattcttgg atacccaatc cacgaagcgg aaaaagcaga attcttcatg cagttcacga 294061 tcttcccggt gaagagaaca gaagcgctga tcagcaaggt gaagaaatat gcggatgccg 294121 ctgtgaagga cggcaaaacg ccggaggact tcatgaagca ggaattcaac aacgttctgt 294181 tcgcgttgtt agctgagaaa gatgaagagc cacaagcaga gaaagcggaa gtaagcactg 294241 ttgagtgggc aaacgacttg gagaaagaaa ccgctgcggc tattgaagaa ggcatgagcg 294301 gggaagagta tccgactgaa ttgatcccag ctgttattga catctggaaa acattctgcg 294361 agaaaaaatc acctgtcatc agaaagccgg aagcttttgc ggcggcagtt gaatattatg 294421 taaacgcaat ttctcttaac ggcgcgtccg tttcccaggc taaactggcg aaaaaatacg 294481 gcgttagcgc atcaacgatt tccagccgtt acaaagaaat tgaaagcacg ctgcaagatg 294541 aagcagatcg ttttgcacaa gcgttatcct cataatggaa aaaaccttga aaagccaggc 294601 ttttcaaggt ttttttattt ctgaaacgga attttgattt ctaaccggaa gatggggtgg 294661 cggtaggtaa aatccagcct gccaaaagcg cccttcacca gtttttgaat gatatatgtg 294721 cccatgcctt catgagcgcc gtttttcgtt gagcggccaa acgattgata aattgtatcg 294781 agcacttttg ggtccatccc gggagtgctg ttttcacaag tcagtacata aagcccgctg 294841 cgcagtgaag tctccagttt aatctctgct ttttctcggg cctccgccgc gctgtcgagc 294901 gcattttcta atatgttgcc gaccaagctg acctgatcag caggcgaaaa cggaagggaa 294961 gaaagcggtg tatgcatatg cagcgaaaca ctcacattcg aggcgcgggc tttttctaaa 295021 aaatcataaa gcacccctgc aacgtacgcg ttctctcctt tcaaaaaacg gtcatattgg 295081 ctgtattgat ccgcccagtt ttgaatatat gcttgtgtat ctgccttggg ctgagctgat 295141 ttgattgcag tgatatgttt cattgtgtca tgattccggc ttctgacatc aatcagcatt 295201 tgattggcgt gctgttcagc ttgagtcagc ttatcaattt gatcagaaag ccttgcctgc 295261 aaagcagact gtccgatacg gagcccttca caccctgcaa atatcgcgat tacacataat 295321 accggcatga tgtctgtgcc aatcaacacc actcccaccg acatcacttg aatcaccgca 295381 atccacgcac aaagccctga ggaacagtgt ttccacaccc gcttcgtatt ccaaatgtac 295441 aatcctgcag cagctgcgcc taaagcagcg gcgagccaag aggcggctgt gctgtgtgaa 295501 aaagcagcag ctccctgata acatatgaaa ctaaataaaa tcagataaag acattgaaaa 295561 agggtaatca cgtactaaac tcctcaaaaa tagtagtttt gaaaataatc aagctgctgc 295621 ttagtgatca tcgctttttt agacgttccc tcaaaggaaa ctgtgaatga atgcttggta 295681 taagcggaaa aatgctttat gtaatgaatg ttgataataa aggaacgatg cgaacgaaga 295741 aaatcttttt cgggcaggtc gcctttaata tcatttaatg tttgatacgt ttgcacctct 295801 tcggcggttg tcacaatcgt cgtcgaacgt cccgtccgtt ctgcgaaaat aatatccttc 295861 ttttgcagga cgtgcatttc agacttttgc tttatcaata tacgcccatt caaactcgtt 295921 tccgttttct ttttcaagta ccggtcgaag gaagcggcca gacggtcggc atagtacggc 295981 ttcataatat aatcatggac gttcaggtca aaggcgtgaa ccgcataacc gccgtggccg 296041 gtaacaaaaa tcacatccac atcaagtgaa tgggatttga tcaaatcagc aagctcgtag 296101 ccagacatat ggggcatctc gatatcggca agcagcagat caatgtctcc gttctttacc 296161 cgcctgtagg cttccttcgc tgaatcggtg gaaaagacaa tttcgacgtc ctgcattctg 296221 gacacgatcg cttctaactt ctctaaatct actcgataat catctacaag tccgactttt 296281 accattatca ttcccctagt tacatagaat catctttatt ctatcccatt tcacgacata 296341 aaaagaactc ttcgcgacaa ctttatccaa ctaatccagc ttttcgtata tagtcattac 296401 tagaaataaa gataagggag attgtgacat gattacactg accgattgca gccgcaggtt 296461 tcaggataag aaaaaagtag tcaaagcggt gcgagatgta agcttaacaa ttgaaaaagg 296521 agaagtcgtc ggcattctcg gagaaaacgg tgccggcaaa acgacgatgc tgagaatgat 296581 tgcttccttg cttgaaccat cacagggtgt aatcacagta gacggctttg acacggtcaa 296641 gcagccggct gaggtcaaac aaagaatcgg tgtcttattc ggaggagaaa ccgggcttta 296701 cgacaggatg accgctaaag aaaatctcca atacttcggc aggctgtatg ggctgaaccg 296761 ccacgagatc aaagcaagaa tagaagattt atcgaaacgg ttcggcatgc gcgattatat 296821 gaaccggaga gtgggcgggt tttcgaaagg catgaggcag aaagtcgcca ttgccagagc 296881 gctgattcac gatccggaca tcattttatt tgatgagccg acaactgggc ttgatattac 296941 gtcaagcaac atcttccgcg aatttataca gcagctgaaa agagaacaaa aaacgattct 297001 tttctccagc cacattatgg aggaagtgca ggcgctctgt gacagtgtca tcatgattca 297061 cagcggagag gtgatttacc gaggggcgct tgaatcacta tacgagagcg agcgcagtga 297121 ggatttgaat tacatcttta tgtctaagct tgtcaggggg atttcttaaa tgctgagcca 297181 tatttataaa aaagaaatga tcgacgcttt acgcgacaga aaaacgatat tactcacaat 297241 cttagtgccg atgattatga tgcttggact tgtctttttt tatgaaagca tgctgtccga 297301 caaaggggag cagtacacgc tggctgtcgg ccattcgctt ccgcccgcac tggaaagcaa 297361 gcttaatgag attgacgaaa tcagcgtaaa aacatttgca aagcctgaag aggcagttga 297421 tgaaggaaaa gcagatgcct atctgaacgt cccgaaagag ttcgactcat atgtcaacag 297481 catgacacct tttaaggttg atgtttacgg caattcaatc gatcaagggt cgtcaaatgc 297541 catgcagctt gtgcagtctg ccttagatca gtacaaaaat gaaattgtgc agcaacgttt 297601 aacaaataag catattgatc aatcggtgat ccagccgttt acaattcagc aaaaggaagc 297661 ggatgaggag aaagggactt ccgctattat gctttccgcc attctgccca tgctgattct 297721 gacttccatt gtttccggcg caatgccgat cgctcttgat atcatggccg gtgaaaagga 297781 ccgaaagtca atcgaggcgc tgctattaac gccagtcagc agaaacaaag tgctggtcgg 297841 caagtggctt gcggtttcca cttttggcgt ggcttcaggt gtatttgctt tggtgttttt 297901 gattttgtcc accgtgttat ttaccgaaaa tttaaaaacg gccttccagc tgggagatca 297961 tatgtggagt gtaatcggcg cttcagcctt aatcattgtg ctctctgcat tgctgatatc 298021 tgcgatggag cttttcatca gcatcatgtc cagctcggta aaagaagcgc aaagttatat 298081 gtctctcgtc gtctttctgc ctgtgttccc gatgtttttc atcttcagca aggcaccgaa 298141 ccaatttgac ttatcatact ttctcatccc gtttctgaac ctgcatgcgt tatttaaaca 298201 gcttttattc gggatggttg acccggctac cattttgtct acgtcaggaa ccatcgccgt 298261 gctcatcgcc atcttctttt tactagccag agcctgcttc ctgaaagaca aatgggttct 298321 tccaaaataa acttgcgaaa ggagaaatac actttctcct ttttgtatat cctgaaaaaa 298381 gaaggaaaat agaaaaagga tatctaatac aaaaagtgac cctgcactat ttttcatcaa 298441 aattggtttc aaaggagaag gaacaatgga tcaaacacgt acactcggca aaacgaagct 298501 gaaggtgaag cggatcggat tcggcgcgaa tgcggtcggc gggcataatc tatttccaaa 298561 tctaaatgat gaaacaggga aggatttagt gcgcacggca ttggatggcg gcgtcaattt 298621 tatcgatacc gcctttatat atggattggg gcgatctgaa gaattaatcg gcgaagtcgt 298681 acaggaacgc ggcgtgcgga atgagctcat catcgccacc aaaggagctc ataaagaagt 298741 ggacggcagc attgaattag acaatagccg ggagtttctt cgcagcgagg tggagaagag 298801 cctgaagcgg ctgaaaacag attacattga tttgtattat gttcactttc cggatggaaa 298861 aacacctctc gctgaagtgg cgggcacttt gaaagagctg aaggatgagg ggaaaatcaa 298921 agcgatcggc gcttcgaacc tcgattatca gcaattgcag gattttaatg ctgacggcta 298981 tttggaggtc ttccaggccg aatattctct catacagcgt gatgccgaga aagagcttct 299041 tccatactgt gaaaaacaag gcatctcctt tattccttac tttccgcttg cgtccggact 299101 gctgacagga aaattcacgc aagacacagt ctttgatgat ttcagaaagg ataaacctca 299161 atttcagggt gaaacgttta tccacaatct caaaaaagta gataagctga aagcagtagc 299221 ggaggaaaaa caagcggata cggcacatgt cgccttggcg tggctgttaa cgagaccggc 299281 gattgatgcc attattccag gagctaaacg accggagcaa ttacaggata acctgaaaac 299341 cttgaacatt gaactgaccg aagatgaagt gaatttcatc agcgacattt tcaaataaaa 299401 aaggaaatag ccgtcatggc tatttccttt tggtgtttta ttctttgatg aatgcttcga 299461 ctaattctgc tgctctgtaa tcatccatat caagctgcca ttggtcgatg tcatttttct 299521 tcattttcac ttcaactgtt ttttcagatg aagcaggtcc aagctttttg aattcctcag 299581 gatagacttg aagcgcgtat ttcactgcct cttcatagct ggcactagag tttttactgt 299641 agtagtcttt cactttgtct tcgatgcggt ctgaaagaga agatgcatct acaggtttaa 299701 ctgtggcttc aacaattgct tcgtctttag agattgaagt cgtttttgct tgaatggaag 299761 agtttttgct taatccctct ttaatgccgt tcacgatatt atcaagcgct ttgctgtccg 299821 catatgtgct ggaaaggccg gaagctgaga gataaccgtc tttggctgat tcattaaaat 299881 catttacaat ttcatttttg ttagcgccgg tgattttttc gaaatcggcg ttatctttgc 299941 cgaaaagaag gacatcaaca taagctgata acgcttttgc agaatcttgg agcttatctg 300001 ccgtcgccag gatttttttg tcttttccgt caattttaaa agtaactgat tttggctttt 300061 tatcaccgta agattccggc gtatagttaa gctcgtattg cttgccttta tctacaacga 300121 agaaaagatt tccttcaacg gatttgtcag cgttaatcgt gctgccctga agcttttcgc 300181 tatagtcttc agggtctgtg tcagacattt tggtatcacc ttgatacaat gtgaaatcca 300241 tactgtctac attcagcggg tcttttcctg tgtttttcac cgcgacattg acttttaaca 300301 caagctggtc atctgaagtg gacttatcat atttagacgg aagtgtgtaa gagacatcct 300361 tgattttgac ttgagctata tctgagcttt tttctgtttc tgattctttc ttctccgcgc 300421 ttgttttgct gccggaacaa gcagctgtaa acatcatcag cagaagaatt aggaaaacag 300481 cgtacgtttt tttctgaaac attcattttt cctcctcaaa tggtttagga aaggggagtc 300541 ttttgtcttt gagaaatgga tctttttgaa tggattagca tcatataacc aaaaaaatca 300601 gttcttttct cacggttttc accggatttt ctggaaactc cgccctcctt tgtcatgaat 300661 ggacctataa aaagttacaa cggaattaat tttaagatta ttagctttta tattgaatag 300721 gttcatcatc ctatttttgg tgaaaaatgt tctggtaaaa ctggtaaact cagaaaactg 300781 tgtattttag actattactt tttgattagt tggagggaac ttaagaagga tgaaaggggc 300841 cgcctttgtg aagaaagagg gactgaaaca aaaagcactg gaaatcggcc gggtgccgac 300901 acacttaaaa ctggaaattg aagattatgg cggtgatgat aaaagagctc atttttgttg 300961 ggcagatcct caggatgaga ataccggcat tatcgtggag cttggaccgg acggagagct 301021 ggaatccctt tcccgtgata ttgagcctga aagcggagaa aggctgtctg aggagaaact 301081 agaggatatc atgcgccaat ttgtcgagac tcatcatccg ggggcactct ctgcctttgt 301141 tcgtgaagaa aatgaccgtg catacggcga taaagtgaga ttttcatatg ttcaaatgga 301201 ggctgggctt cctctcccca tgagcggatt tatggctgat gtttccttat caggtgagat 301261 tgtttacttc cgttattacg gcgaagcggg cagcatcatc aagccaaagc gggtcgcgga 301321 tgttgaagag gcacttgcct ttatcaagaa ggacgtggag ttcgaccttt tgtttgaggt 301381 tctccatcgt tctgtttaca aaaacggaga tgatcagccg catttggtgt acgagcctga 301441 aggtagggcg attaccgtac ctgcggattt ggttcaagaa gaacaagcag ttgatgatga 301501 cgatgattac agggagccgg agagctttcc tctcccttta ttcgagggca tccgcgaaaa 301561 ggccgatcct gacagcatga ttggtattga aaatgggttt gtcaaagagc gggaagcgga 301621 tttgggagat gggagaattg gaatcgtttg gcggaatccg gatgaccctg tgtatcagcc 301681 ggcggataaa agcatggaca gctggtttaa gggacggact catcaagtgc tgaaaaccat 301741 ctataacaaa gaaaccggaa aactcgaagg cgtcatgtca tttatggaga aaaaagggcc 301801 gctgacagta accttggcag agtgtgaaaa aatcgcgctt cgctttctat ttgctttatt 301861 tccgaatgcc gatcaatatt ttaggatcag atacgacgaa aaagatgaag aagaaaacgc 301921 agtcgctggt tttacgtttg aagcgcattg tcacggagtt ccgctccgat ttgggcagat 301981 cagaatttgt gtcagccgcc agacagggta tatcaccgtt tatatgggac cggatattga 302041 cccaaataag ctggcaacca ttgatcctgt gccggctatt tcagttgaac aagccaagtc 302101 tatcttttgg cagcatttta aagttgagct tggctgggaa agagagtacg gggatgatga 302161 agaacacagc taccggctcg tctataagcc ggtgtatccg cattttatcg atgcacatac 302221 aggggagcct gtcttcagca tatggtgaaa cagccaaaag tcacgcaatt gcctcagata 302281 tagaagagag tatgtgatga aagtaacaga aagaatctca aaaaacaatg acaataatag 302341 aaaaggacct ttcttcactt taaatgaaga aaggtctttt tatataataa acaggattct 302401 ctttgtcgta gactctttga aagggatgac ttcattggtt aataaacagc tgaaaaagaa 302461 ggcgcaggag atcggaaatg taccgacgca ttatgagctt gagatagaag attacgacca 302521 aaagcaaaag aagtacgggc aggcatattt tatctggaag gaccctaaag atccggaaaa 302581 gcacattaca gttgaactta gaaatgacgg cgccttgctc accttttcaa caactgtcca 302641 ctccgagaca gacaaaaaac ttccagatgc cgagctgaag ctgacggctc ttcagtttgc 302701 cgctgccaat catcccggca catttatgaa ttttcatttt caaggcaagg aagaaagggg 302761 gcagcacatc cggtttgtct ataccaaaat ggagctgggg cttccgattc ccaattcagg 302821 ctttttaatt gatatgacac gaagcggtca gattgtccac tttctatatt acggggaagg 302881 gcataaagcc gaagttccga cggaatttgt agcaaaagag aaggttgtat cccattactt 302941 aaacacaatg tcttttgagc tgatgtacga tgtcattgat ggcgaacagg aaccaaggct 303001 tgtatatgaa ccgattctac cgggatacag ctatcccgca gatgtagacg aaattgtgcc 303061 cgaccagcat atcgcagatg aaagaataga aaacacggcg ccactgccgc cgcttcagaa 303121 caaggaagaa gttgatatat ttgccttgct gggttttacc tctgatatgc agaaagtcag 303181 tgaaagagac tttggagaac aaattggaag cacgtggcgc aggggcgctg cgccggagcg 303241 taaggattta agcataggaa gctattttga aacgagaaat aaaaatacaa tcaaaatgaa 303301 gacggataaa agaaccggaa aattaaaagc agcgctttct tttatggact ggcggaacaa 303361 cctccaatgc tccacggaag aatgccaaga gatagcgctt caatttttgt atgccctcta 303421 tccgagagcg gctgagtttt tcagggtgaa tcccgtccga attgatgaaa gagggagagt 303481 ccgcaaccat ttttctgtct ggtataaagg agtgccgctg cggttcggcg ctgcccgcat 303541 cattgtcaat ccggaaactg ggttgattga cgcttttatg gcgcctgata ttgaacctga 303601 acaattggaa gcgataaatc acaggccgga tgtttccgct gaagaagcga aagaagcatt 303661 tttagccgct tttgatgtga aactggaatg gcagcctgat tttacagcag gcagtgacca 303721 gcactgcaaa cttgtctata agccggttta cccttcctat attgatgcgc acataaggaa 303781 aaagaaaagg ctgtgagggg tgtctagtta ggaatcatct ccaagtgggg gtagtccttg 303841 aatcgtttcc aatccccgcc ccattcgaaa ccgagtgtct tagcgatctc gacaacctcc 303901 agccaatctg attttccgtt ttgattgccg tcatattcca tatcccatat gatgctgcca 303961 tccttttttt gaagggcgaa atcaatcgct aaaccatagt tatgatacga ttcccctcct 304021 cttgcatagg tgacaatatt cccttttttt gtacgtccct gtttatataa ttcatcttgt 304081 tccttaaagg acctgaatcc ttcagtaatg acgacgtcaa tgcctttatt cgctgcagcg 304141 gctttgagtg catcggcatt ctgcttcaca atcggatgaa gatccgaggg gacaggcatg 304201 tcctgcaagg cgttttgaga atgccattca tgccgaatat aactaaaaca aagatctaga 304261 agaaatagaa tacataagat aacaaatgtt tttgcgggta agttcatatc ggtctcactt 304321 tctcaagatg tgctgaatgt taacgctttt aagtgattga ctctctctaa aagcgaacag 304381 ctatgataaa atataacata aatagtagca ggaggaagga ggcagaccga tgagagcaaa 304441 gattccatca gaagaagtag cagtaaagct gaatgaatgg tacaagctca ttcgcgcatt 304501 tgaagcagat caagcagaag cgttaaagca ggagattgaa tatgatttag aagatatgga 304561 agagaatcag gacttgcttt tatatttttc tttgatggaa ttccggcatc gaatcatgct 304621 tgataagctg atgccggtga aagacagcga taccaagcct ccgttctctg atatgctgaa 304681 cgaaattgaa agcaatcagc aaaaactcac gggcttactg gaatactact tttattattt 304741 cagaggaatg tacgaattca agcagaaaaa tttcatatta gcgattgacc attataaaca 304801 tgccgaggaa aagctcgagt atgtcgagga tgagatcgaa aaagctgagt ttctttttaa 304861 agtcgcagaa gtgtattatc acatcaaaca aacgtatttt tccatgaatt atgcgagcca 304921 ggcgcttgat atctatacga aatatgaact gtacggtcgc cgccgggttc agtgtgaatt 304981 tatcatcgcc ggaaatttga ccgatgtgta tcatcatgaa aaagcactga cccacttgtg 305041 cagcgcttta gaacatgcca ggcagcttga agaagcgtac atgatcgctg ctgcctatta 305101 taatgtcgga cactgtaagt acagtctggg tgattacaaa gaagcggagg gctatttcaa 305161 aacagccgcc gccatttttg aggagcacaa ctttcagcaa gctgttcaag ctgtattttc 305221 actgacccat atctactgta aagagggaaa atacgacaag gcagtagagg cttatgaccg 305281 cgggataaag agcgcggctg aatgggagga tgacatgtac ttgacgaaat tccgcctcat 305341 tcatgagctg tatcttggaa gcggcgacct gaacgtgctt acagaatgct ttgacctgct 305401 ggaatccagg cagcttcttg ctgacgccga agatctgctg catgatacag cggaacgttt 305461 caatcagttg gaacattacg agtccgccgc tttcttttac cgcaggctga tgaatattaa 305521 aaagaagctt gccgagcagc gttttcaata ggaaatggca gagaactaca ggttctctgc 305581 tttttttgtg ctgttttcaa ctcggaaaaa cagggtattt tccactgcat agtgagaaac 305641 agaggaggat atcaagtatg tacaaagatt taaccggaaa aacagcgatt gtgacagggt 305701 cttcaaaagg aatcgggaaa gccattgcgg aacggttcgg aaaggagaaa atgaatgttg 305761 ttgtaaatta ccacagcgac ccgtctggag cagatgaaac tctggaaatc attaagcaga 305821 acggagggaa agccgtctca gttgaggcgg acgtgtcaaa agaagagggg attcaggcgc 305881 tcttggacac agctttagag catttcggca cgctcgatgt gatggtaaac aactccggtt 305941 ttaacggcgt tgaggcgatg ccgcatgaga tgagtcttga agattggcag agagtgattg 306001 atgtcaatgt taccggaacc tttctgggag cgaaagcagc acttaaccac atgatgaaaa 306061 acaatatcaa gggcaatgtg ctgaatatct caagtgttca tcagcagatt ccgcgccctg 306121 taaacgttca gtattccaca tccaaaggcg gcatcaagat gatgacggaa acgctggcgc 306181 tcaattatgc ggataaggga atccgcgtca atgcgatagc gcccggcacc attgccacag 306241 aatcaaatgt tgatacgaaa aaggaagaga gcaggcaaaa acaattgaaa aaaatcccga 306301 tgaaagcctt cggaaagcct gaagaagtgg cggcagcagc agcttggctc gtatctgagg 306361 aagcaagcta tgtgaccggc gcaacacttt tcgtcgacgg cggaatgaca ctttatccat 306421 ctcagcttga atagaagaca aaacaggggg attgcgggat gaaaacagac tggtggaagg 306481 atgcagtggt gtaccaaatt tacccgagaa gctttcagga cagcaatgga gacggaattg 306541 gggacttgcg ggggattatt tcccgtcttg actacataaa ggagctcggg gcagatgtga 306601 tttggatttg cccgatctat ccttctccga atgttgatta cggctatgat gtgacaaacc 306661 ataaggcgat tatggattct tacggaacaa tggacgattt tcacgagctg ctggaccagg 306721 tgcatcagcg gggattaaag ctggtgatgg actttgtgtt aaatcacacc tcggtcgagc 306781 atccgtggtt taaagaagcg gagctggaca aaaacagcaa ataccgtagc tattattatt 306841 ggcgtcccgg cacaaagaac ggcccgccga cggactggct ctcaaactat ggatgcccgg 306901 tctggcaata cgaagagcac accggagaat actatctcca tatgaatgcc gtcaaacaag 306961 ctgatttaaa ctgggaaaat cccgaagttc gccaggcggt gtatgacatg atgaaatttt 307021 ggctcgataa aggggtcgac ggtttgcgaa ttgatcagct ccatctcatt tctaagaaag 307081 aatatcttcc ttcgtatgag gactatatca atcagcaggc agagccgaag ccctttcagc 307141 caaatggcga acgaatccat gactatttaa aagaaatcac agatgaagtg ttttctcatt 307201 atgatgtcat gtctgtcgga gaggtcggca gtgtcacacc ggaagaaggc ctgaaatata 307261 cgggaacaga taagcatgag ctgaatatga tttttcactt tcagcatatg gagcttgatc 307321 agcagcccgg aaaagaacat tgggatttga agccccttga gctttctgat ttaaaatcgg 307381 ttttgacaaa atggcaaaag aagcttgaac atcaaggctg gaatacattg ttttggtgca 307441 accacgacca gccccggatt gtgtccagat tcggagacga tggggaatac cgcaaagcat 307501 cagcgaaaat gctggcagcc gtaatttatt ttatgaaggg cacgccgtat atttatcagg 307561 gagaagaaat cgggatgaca aacgcgccgt tcacccggat tgaagactac aaagatatcc 307621 aaacgatcaa tatgtatcat aaacgggtgt ttgaaaaagg ctatgatcca aatgatgtga 307681 tgagatcgat cttagccaaa agccgggatc acgcccggac cccgatgcag tggaacagcg 307741 gcaaaaatgc cggatttact gacggcacgc cttggctgaa ggtcaatccg aacttcaccg 307801 caatcaatgt ggaggaagcg cagggagatc ctgattctgt cttaaactat tacaaaaagc 307861 tgatcagcct gagaaagcag tacgctgacc tcatgaaagg gagctttgat cttttgcttc 307921 cggacgatcc gcagttgttt gtatacatga gagaaaacag taaacaacag cttttgtcgg 307981 tcaataattt ttcaaaagag caggctgttt ttcagtggcc taagaactgc ggcaaagctc 308041 aggcctcact gcttctcagc aattataaca acgatgatct tgatgacgaa atggtgttcc 308101 ggccttatga gagcagggtc tatcttctgg acaaaacaaa ctaatgattg aagtagcccg 308161 gcatttttag ccgggttttt ttagtacata tattcgctct gcaggcggga agaataaatg 308221 aaaatgaaat ttattcttgc aaaacgtaat gacttcggtt tattatgata taggattaca 308281 aaatcgttat cattttgatt taaagttact gaaaaagagg ggatatacga tatgtttaaa 308341 aaatggagcg gtttgtttgt gattgcagcg tgctttttat tagttgcagc atgcggcaac 308401 tcatcaacaa aagggtcggc ggattcaaag ggtgataaac tgcacgttgt cacaacgttc 308461 tacccgatgt atgaattcac aaaacaaatt gtaaaagaca aaggcgatgt ggatctgtta 308521 atcccatctt ccgttgaacc gcatgattgg gaaccgacgc cgaaagacat tgccaacatt 308581 caggatgctg atttgttcgt ttataatagt gaatacatgg agacatgggt tccgtcagct 308641 gaaaaaagca tgggccaagg ccatgccgtt ttcgttaatg caagcaaagg cattgattta 308701 atggaaggct ctgaagaaga acacgaagag catgatcatg gggagcatga gcacagtcat 308761 gcaatggacc ctcacgtatg gcttagccct gttctggcac agaaggaagt taaaaatatt 308821 acggctcaaa tcgtgaagca ggacccggat aacaaagaat actatgagaa aaatagtaaa 308881 gaatatattg caaaactgca ggatcttgat aaactatatc gtacaaccgc aaaaaaagcg 308941 gagaaaaaag aatttatcac gcagcataca gcttttggct atctggcaaa agaatacggc 309001 ttgaagcagg ttccgattgc agggctttca cctgaccaag aaccgagcgc agccagcttg 309061 gcaaagctga aaacatatgc caaagaacat aatgtaaaag ttatttactt tgaagaaatt 309121 gcatcctcaa aggtcgcaga tacgctcgcc agtgaaatcg gcgcgaagac agaagtgctg 309181 aatacactgg aaggcttgag caaagaagaa caggataaag gtttagggta tatcgacatt 309241 atgaaacaaa acctcgatgc cctgaaagat tcactattgg ttaaatcata agatagtgtg 309301 cgccggaggg gtgcacacta tttctttgtg agaaaggaag attaacatga atctcgtctc 309361 attgaaagat atcgttttcg gctattccca tacgcctgtt ttagataaag tatcacttga 309421 tattgaaagc ggtgagttcg tcggcatcac tggaccaaac ggcgcctcta aatcgacgct 309481 cataaaggta atgctcggca tgctgaaacc gtgggaaggc acagtgacga tcagtaaaag 309541 gaatacagaa gggaaacgcc tgaccatagg gtacgtcccg cagcaaattt cttcatttaa 309601 tgccggattt ccgagcacgg tgctggagct tgttcagtca ggccgctata caaaagggaa 309661 atggtttaaa cgtttaaatg aagaagatca tcttgaagta gaaaaagcat tgaaaatggt 309721 ggaaatgtgg gacctccgcc atcgtaaaat cggtgattta tcaggcggac agaaacagaa 309781 aatctgtatc gccagaatgc tcgccagcaa cccggatctg ctgatgctgg acgaaccgac 309841 gacagctgtt gattacgaca gcagaaaagg attttacgaa tttatgcatc atctcgtgaa 309901 aaatcacaac cgcacagttg tgatggttac tcacgaacaa aacgaagtac agcaattttt 309961 agataaagtg attcgattag agagaggaga aaaaggcgga tggaaatgtt tgacttggaa 310021 ttcatgcgac gagcttttct agcaggcggc atgatcgccg tcatggctcc gatactagga 310081 gtgtatctcg ttctcagaag acaggcctta atggctgaca cactttcaca tatctcattg 310141 tcaggtgttg ccatcggctt ttttctcagc accaatataa ccgcagcaag catagtcgtc 310201 gtgaccatcg gcgcgatcgg aattgaatac atgcggcggg cgtatcggac ttattcagaa 310261 gtgtccattg ccatcttaat ggcagctggt ttgtccttcg cgatgttttt aatcagcctt 310321 tccaaaggca cagccaatat gagcatcgat caatacctat ttggatcgct tgtgacagta 310381 aaccagcagc aggtctatat tatcagtatt atcacactgc tgatcctgct ttattttatt 310441 gtactgagaa ggccgctcta cctgctgacg tttgatgaag ctacagccaa aacatcggga 310501 atcaatacaa acgttctctc gttgtcattc agtattgtca caggccttgc gatttcagtc 310561 attattccga tcatcggggt ccttcttgta tcggccctgc tcgtattgcc ggcagccttc 310621 gccatcagaa ttgcaaaagg ctttaacatg gttttcatta cagccatact catttcatta 310681 ttcagcgtat ttacgggact gacatcatcc tatcagctcg ggacgccgcc aggtccgtct 310741 attaccctgc tattgatcgt tttgctatta atcggatttg cagttcaggg agtttggacg 310801 tttatcaaaa aagaagctca gcgcaaaaaa agaagccgat aacatgaaaa gcagttttcc 310861 ctagggaaaa ctgctttttt tatagaaaca attcggcaag gcgctcataa gattcttttt 310921 tcgcctcaaa atcaaacaca ttgcacagaa ccatgatttc atttgtttcg tagcagcctg 310981 tgaggtctaa cagctgttgt ttgacagtgg tgggagaacc gatcaccatc cgctttctgt 311041 tttcttctat gagtttttta tcggacgctg tatagggatg agctttcgct tcctcgatgc 311101 ttggcacgcg gctgtccaag ccttttccga cgcgaagaag ccacagatcc tggcttaatg 311161 cgagttcttc tgcctcttca tctgtttttg cgcaaatgac aaaaatcgta aacagtgcgg 311221 atggattcga aaaatgggct gagggccgaa agctttcccg gtagatgcgg aatgcatttt 311281 ctcctcgctc gggattaatg aaatgcccaa atacatatcc aatcccctgg tgcgccgcgc 311341 gtcttgcgct gttttcacca agaccgagca cccatagctc gggtgccgta ccaataaggg 311401 gcgccgcttt gattccggca tacggatggt cgggaggaag ggaatctgtt agaaaataag 311461 agacatcctg cagctgtctg ttaaattcgg ttaagctttt tttcaccccg tccgttaatg 311521 caagtctggt ttttgtcgtg ccgccggggg agcgaccgac gccgaggtca atccggtttg 311581 gatacagggc ctcaagctgg cgaaaggttt cagccacttt aaatgggctg tattggggca 311641 gaagcacgcc gcctgatccg acacgaatgg tgtttgtctg tgctgcgatg cgggcgatca 311701 tgatttcagg cgctgtgctt gccagtcctt tcgtgctgtg atgctcggca aaccaataac 311761 gcttatagcc ccactgttcg cttaattggg caagctcaac cgaatgctgg agagttgtca 311821 cagggctttc tcctttagaa acaggtgcct gatcaagtat gcttaaatga atcaaaaggc 311881 cgcttccttt ctgtctgttt ttagatggtg acaccagaat aggcaaaatg acttgcccgc 311941 gtcaaatggt ttgtttaaga agcgcacttt atagcatttg caaatcatat atcaaatatg 312001 gaagtttttt ttcgaggttt ttcgtcaatt attcttaact tttacgaaac tttgatataa 312061 taacaaacgt atatattagt aatttacggc ttattttcct tgtgagcgta aaaataaatg 312121 tgactatctt cacattttga tgagtaggag tgaatcgtgt ggcaatttct ttagaaaaag 312181 gtcaacgaat tgatttaaca aaaggaaaag ccggtctgtc aaaattgatg gtcggtctcg 312241 gctgggaccc agtgtcctca ggcggaggat tcttcagcaa actgcttggc ggaggcggtc 312301 cgaatatcga ctgtgacgct tcagtgctga tgctggaaaa cggaaaattc accgataaga 312361 aaaacctgat ttatttcggc aacctgaaaa gccgctgcgg cggtgtacag catacaggcg 312421 acaacctgac gggtgacggt gcgggcgatg acgagcaaat tatgatagat ttagataaag 312481 tgcctggaaa catcgataag cttgtatttg tagtgaacat ttacgattgt gtcagaagaa 312541 aacaagattt cggcatgatt caaaatgcgt ttatccgcgt agttgatcaa tctaatcacg 312601 aggaaatgct caagtacaat ttgagagaca attacgccgg cagaacaagc ctgattacag 312661 cagaaatcta ccgcagcggc agtgagtgga agtttgcggc ggtcggtgaa ggcacaaacg 312721 atacgagatt agaagatatt atcagtcgat acgtataaaa gaaaaggagt ggatgaaaca 312781 tgacaatttc attggcaaaa ggacaaaaag tagatttaac aaaaacaaat ccgggtcttt 312841 caaaggttgt tgtcggttta ggctgggata cgaacaagta tgacggcggg cacgactttg 312901 atcttgactc aagtgtgttt ctgttagacg ccgcgggcaa atgcgcgtca ccaaacgact 312961 ttattttcta caaccagctt gaaggcggca acggttcagt cgttcattca ggcgacaacc 313021 tgactggtgc tggcgaaggc gacgatgaga atgtaaaagt aaatctcagc gctgtaccgg 313081 caaacattga taaaatctca tttgttatta ccattcacga tgcagaagcg cgcagccaaa 313141 actttggaca agtatcaaac gcgtttgtcc gcatcgtaaa tgaagaaaca aatgaagagc 313201 tcatccgtta cgatcttgca gaagatttct ctattgaaac ggcaatcatt gcaggggagc 313261 tttacagaca taacggcgag tggaaattct cagcaatcgg ctcaggctac caaggcggcc 313321 ttgcccgcat tgcaacagac tacggtttgc aagtcggtta agacaaatac gaagagcaga 313381 aaggagagag gcagtatggc cattcaatta tcaaaaggac agcgcattga tttaacaaaa 313441 acaaatccgg gactgactaa agcggtgatc ggcttaggct gggatacaaa caagtactcc 313501 ggcggacacg attttgacct ggatgcttcg gcctttttag ttgatgcgca tgataactgc 313561 gtaaatgatc tcgatttcgt cttctataat aaccttgaac atccgagcgg cggtgtcatc 313621 catacgggtg acaaccgcac gggtgagggc gacggagatg atgagcagat tatcgttgat 313681 ttctcaaaaa tccctgctca cattgagaaa atcggcatca cagtgaccat tcacgacgct 313741 gaagcacgca gccaaaactt tggacaagtt tccaatgcat ttgtccgcgt tgtggatgaa 313801 gaaacgcaga atgagcttct tcgcttcgat ttgggagaag acttctccat tgaaacagct 313861 gttgtcgttt gtgagcttta cagacacggc ggcgagtgga aattcaatgc aatcggcagc 313921 ggattttccg gcgggctggc tgcattgtgc cggaattacg gtttgcaagt gtaagcgagt 313981 gacaaataga gaagtcaccg tttcaaatta taggaggaaa aaacttggac tttttacatc 314041 atattttgtc tacgtatgct tcatttttcg attggaaaat gtggggggaa gttctgactg 314101 atcctgtttc ctggggtttg atcggttccc ttgttgttct ggaaggcctt ttatcggccg 314161 ataacgcgct tgttcttgcg gtcatggtta aacacctgcc ggaaaaacag cggaaaaaag 314221 cgttaacgta tggtttgttt ggagcttata ttttcaggtt tattttcatc gggctcggta 314281 tgcttctcat taaattctgg tggatcaagg tgcttggcgc gctttacctg gcttggctcg 314341 tcattaagca cttctggata ggcgaaaaag aagaggaagc ggacggcatg aagaaaaact 314401 cttggatggt ccgcacgttc gggatcttct gggcgactgt catttcagta gaattaatgg 314461 atcttgcctt ctctgtggac agcatcctgg ccgcgtttgc agtatctgaa aaagtatggg 314521 tgcttctgat tggcggtatg cttggtattt taatgatgcg tacagtggca aaagtgttcc 314581 ttgtgctgat tgataaaatt cctgagctgg aaaacacagc attcgtctta atcggcatta 314641 tcgcgctgaa aatggcgggg agcgctttcc attacgaaat gccgcactct gtattcttca 314701 ttatcattat cgctgcattt gcggtaacat tgatcattca ctacatcaat aaacaaaagc 314761 aggtgcgcga acaaacagcc gcttcaaaag aagaataaaa caaaacaagg agggaggttc 314821 aatgtccttc cttttttgtt accgaaatat cgtttcaatg acaaaccgga aaggaggata 314881 tgatgagaca agaagaacta accattcata aagcacttcc ggctgatggc gattggaaaa 314941 gcctgctgtt tcagccattg ccggagcggg atcactatga aactgcacaa ggcctttctt 315001 tttctcgtct tgccggtcag atattgggca cgcctattga tgagacggac tactataacg 315061 agctgtatga gctgtctgta aacgaccgca taacgatttt gagtgaaacg cttgataaaa 315121 caatcgaacc ggaaacattt caaaagcttc agcatattca ttccatcaat cagaaagaaa 315181 aagggctgtc agtcagccgc tttgttgcct ttctggacgg ggaaaagctg attgcgaagc 315241 actcaaatcc cttgatgcac cgccatttaa gaaaagcgtt gatgacgctt ttacatacct 315301 ttgcggacag tcatgaaaag gggctgaatc atcctgattt tcgcagagtg ctgcttgatg 315361 tctcgaagtt ttccttaaac catctgaacc cttggctgga aaaaaccgat atagagcggg 315421 agatgccgaa ggttgtttgg tatggagatg cgacgaaaag ccagctctat ttcttatatt 315481 atctgatgct ggtcggctgt gatgtactgc tgttccatcc ggcgggaacg gatcagctgg 315541 cgcttgtcga cccgaagcag gagctcggtt ttacggaaaa gctcccggat gtttcggagc 315601 ttcagccgtt tccgaaagaa aaaccagacc ggaaatcaac agtggcttac cgctcaacaa 315661 aggaaattga acatgtgctg aatcacgagg aatccatgct atataagccg tggcagttca 315721 gagatcacac accggtgtcc gttacgctga aaacgaccta tgatgaattg tttttaatca 315781 cgaaagaacg cgcctttatt cggccgaatt tcaaagctga taaacattcc attgagattc 315841 cgaatgtatt cgccaaaatt atgggcgtgt cgaaagacaa taaggaatat tggaacaggc 315901 ttcatactct agcggattat caggaaacag aaatggtcag aagctttcca tttacagaag 315961 aaataaagtc gaactatcaa tttcactaca gccacgcact tgatcaagaa gggaacattg 316021 atccggacaa gctgatggca agcaatgtgt ggcagtacaa acagctgccg gcgggcgttc 316081 agactgccat tgccaaaacg atttcgagaa tgtgcaggta cccgcggctt aaagccttgc 316141 atcaggaaca agtcaaggat gttcaaatct atttgtttaa acaaacaaca aacctgcctg 316201 ctaatctgct gaaattgatt caaatgttcg actatgcgca aaccgttccg aaactcgttt 316261 tatatcatac ggaaatgagc ggcggactca cgcgttcgga tgctgccgcc ctgctgttcc 316321 tgaatgaaat cggaatcgat atcatcattt ataatccgcc cggacaccaa gatattgagc 316381 agtttattga agaggatcag tatgatatcc actggctgga tgacatggtg tttcagcagg 316441 actacaaaga gccttcgctt gtgaaaaggc tcttcagaac cattacccaa aaataaggag 316501 agaagaaaag catgacaaca gaaaatcaaa atccgcttgt tctcgataaa aatgaagaga 316561 tttcccagca aaaagctgac gatatccgtc ttcagctccg tcaggaacca gaagtgaagc 316621 ggcttgctca acaaattgac gtcaaaaacc aaatggagct gcttgagtac ggcaaggagc 316681 cggccgttga aatatccaag ttctctgacc gcatcttggg gatgatgaaa acaacaagcg 316741 tgacagactc cggcacaatg ctgactcagc ttgggaaaat catggaccgc ttcgacaaaa 316801 atgattttga tgagccaaag ggattaatgg cgaaaatttt caaacgcggc ggcagcatga 316861 ttgaaaaaat ctttaaaaag tatcagacgc ttggcggaga gattgaaaaa atccacgttg 316921 agatttcaaa atacaaagat gagatgacga agacgaacta cacgctcgat gaaatgtatg 316981 aaaacaatat caaatactat atggagcttg aaaaatacgt cgttgccggg cagatgaaac 317041 tggaagagat gcagtcgatc cttccttcat atgaggaaaa agcggcaagc gggaaccagc 317101 tggcgcaaat gcagctcgat acgttgcgca acggcattca ggcgcttgag gaacgggtgt 317161 atgatcttga catggcacgg atggtggcgc ttcaaaccgc acctcaaatc cgtctcctgc 317221 agcgaggaaa tgcaaagctg atcgggaaaa tcaactccgc gtttatcatt accattccga 317281 ttttcaaaaa cggcattatt caggctgtta cggtaaagcg gcaaaagctt gtggctgatt 317341 ccatgagcga gcttgaccgc cggacaaacg agatgctgaa acgaaatgct gaaaacatct 317401 cgagccaaag tgttgaaatt gcgagaatgg ccggcagacc gagcatagat attgaaacga 317461 ttgaatcgtc ttggaacacg attgtcagcg gcatgcagga aacaaaacaa atcgaagaag 317521 aaaacaagcg cctccgcgaa gacggcgcga gacgaattgc ccagcttcag gataatatta 317581 aaaaagcagc attgcagcaa taataaaaac cccgcttgtg gaacataagc ggggtatttc 317641 aattacatca tttagttaat gacaatgtgt aaagacaggt gtaaacttaa acggtaatca 317701 ttttgcatat cagaggtgtt ggcaatggga aaacaacagc ctatatccca gcgtaaactg 317761 ctgggcgtcg ccggtttggg gtggctgttt gatgcaatgg atgtcggaat attatcgttt 317821 attatcgccg cgctccatgt agagtggaat ctgtcgcccg aagaaatgaa atggatcgga 317881 agcgtcaatt ccatcggcat ggctgcgggt gcgtttttgt ttggtttgct tgctgatcga 317941 atcggccgca aaaaagtgtt catcatcacc cttttatgct tttccatcgg aagcggcatt 318001 tccgcttttg tgacgagctt atcggcattt ctaatccttc gtttcgtgat tggtatggga 318061 cttggcggcg agcttccagt cgcttcaaca ctcgtttcgg aagcggttgt gcctgaaaag 318121 cggggcagag tgattgtgct tttggaaagc ttttgggccg tgggctggct cgcagcggcc 318181 ttgatttctt actttgtgat accaagcttc ggctggcagg ctgcccttct gttaactgcg 318241 ctgactgctt tttatgcgct gtacctgcgg acgagtctac ctgattcgcc gaaatatgaa 318301 tcgctttctg ccaaaaagag gtcgatgtgg gagaatgtaa aaagcgtctg ggcaagacag 318361 tatatacggc cgacggtgat gctgtcgatc gtttggttct gtgtggtgtt ttcttattac 318421 ggcatgttcc tatggctccc gagtgtcatg ctgctgaaag gcttcagcat gattcaaagc 318481 tttgaatatg tcctgctgat gacgcttgct cagctacctg gctatttctc tgccgcatgg 318541 ctgattgaaa aagcgggccg gaagtggata ctcgtcgttt acttgattgg cacagcagga 318601 agcgcctatt tcttcggaac ggcggattcc ttaagtcttc tgcttacggc tggagtgctg 318661 ttatcgtttt tcaatctcgg tgcgtggggc gtgctgtatg cttatacccc ggagcaatac 318721 ccgactgcga ttcgagcaac aggttcagga acgacagcag cgtttggaag aatcggcggc 318781 atcttcgggc ctttgctcgt cggaaccctg gcagcccgtc atatttcgtt ttcggtcatc 318841 ttttcaatct tttgcattgc aatcttactt gcggttgctt gtattttgat tatggggaaa 318901 gaaacgaaac aaactgagct agaataggaa aagcacctct taaaagaggt gctttcagcg 318961 tgtcgacaaa ccctcgcatt cgttgtcagg actgcgcttc ggtgctcaat gcgaagtgga 319021 tcaacggcta aattctcagg cgtcctgcct aaacgccgtc gtcatcacat cctgtgaatg 319081 tccgctccta tgctcgtcct tcctagactt caagggtttt caatcacgct gaaaagattt 319141 tgtcaacaat ctgaggcacc tcttgaatga ggtgcttttt tacaattgcg cccgggctgt 319201 ggattggcgt ttcccggttt tactgattgt ctggtagagc gtcatagaaa gtatgaacag 319261 aatggcagta aatcctgtga cagctccgaa atgctgtgtg ctttgatata aaaaacctgc 319321 aatacttgta ccgacagtgg ttccggcata catagcggca ttggaaaggg aagcgatggt 319381 tcctcgcgca tttggtgcaa tggattgaaa gacacccatc attaacggaa agatgatgcc 319441 agctgtaaag aacgtgagaa aaaagccggc ttctactaaa aacaagtttg gaaagaacgg 319501 aagagcgaaa tagagagcgc ccattagcag catcccgctg atcagtgttt taaacatgcc 319561 cagcttttct gaaacccggc tgccgataag gctcccgagc atatttccca gtccgagtac 319621 aagcatagct gcgccaattt gtgacacggt taaatgataa tccgcggaaa gccaagtacc 319681 cagaaagctg aacgatgcga agtttccggt ttgaaacaga aaataggcaa gcagaatgac 319741 cgatgttttc ggcaatgaaa aaagctcccg ataggggttg acaattgatg ggcgcgccaa 319801 tggttcagaa ggccggatgc caggcatgac cgccgccagg atcaatagaa gaataagcga 319861 gcacgctgac aaaacgaaaa atggcgtatg ccatgtaaag gaagcgagaa accctccaat 319921 aggaagtccg agcatttgtg aagcggccaa acctgctgtc gcaatcccca tgccttttat 319981 gatctgagaa ggctggacaa tgactgggat ggacgcccaa atttgaggcg tcacaaacgc 320041 agcgctaacg cctgcggcaa aacggaacag gcacatggcg gcaaaagagg gagcgatgcc 320101 gcataaaaat gtggatacga taaagcctgc aagtccccac agcatgactg ttttcctgtt 320161 cagccggtct gagattgggc ctgcaatgaa agcgaagagt gcataaccga gtgcataagc 320221 actgaccatc cagcctgaca aatcagtaga gacatgaaac tgatcctgta aaagggggag 320281 aagcggcgaa agcaaaaagg tatccgtgcc aatgacaaac atgacactga agaaaagcca 320341 aatgcgattc aaattttatc actcctattg ttttataact ttaaaactat gaaacagata 320401 tgtatagaga aaaccctttg ttagagggtt tccaaaaagc caggcaggta tgtttgaaat 320461 gtgtcttcac gcagactgac gtattttgtc cgcgaatctt tccgggttgc cgtcaatccc 320521 gcttcacgca gcgttttaaa atgataagat gccgtggttt tgacaatatt gcacttttca 320581 cctacttcac cgcagctgag ttcttttccg ctgacataaa gcgtacgaat aatggcaagc 320641 cttgattcat cagacagtgc tttaaaaatt tgcgctctga tttgatcatc tgattgtttc 320701 atagtcatga aactataata cataatgggt gttgaaaaag caacttattt ttccagtaaa 320761 ggagcaggaa gtcataagag gaaggaggaa ttcaattcca ataaaagcgt tttcaactaa 320821 aggtaggaga aaaatcaccc gtaaaataca atcatatagg aggattacag agcatttaga 320881 agcataaata agatcatgtg gtcacatgga tgtttataaa gaaatggtac agaataaaag 320941 agaatatgct gtttgtgtgg gaagttacat aaatgttacg gtaataaaga ttgcttaata 321001 tggagggaaa atatgagtgt agatgagaaa ccaattaaga taaaagtcga gaaagtctct 321061 aagatttttg ggaaacaaac aaagaaggca gttcaaatgc ttgccaacgg aaagacaaaa 321121 aaagagatcc tgaaagcaac cggatcaacc gttggggtta atcaggcaga ttttgaagta 321181 tatgatggtg agatatttgt catcatgggt ctatcaggga gcggtaaatc aactttagta 321241 cggatgttaa accggcttat tgaaccgact gccggaaata tttacattga tggtgacatg 321301 ataacaaata tgtcaaaaga ccagctccgg gaagtccgcc ggaaaaaaat cagcatggtc 321361 ttccaaaagt tcgctctgtt tccgcacaga acgatacttg aaaacacaga atacggactg 321421 gagcttcaag gtgtagacaa acaagagcgg cagcaaaaag cgcttgagtc tcttaagctc 321481 gttggactgg aaggatttga acaccaatat cccgaccagc tttccggcgg gatgcagcag 321541 cgtgtcggcc ttgcccgcgc gttgacgaat gacccggaca tccttctgat ggacgaagcg 321601 ttcagtgcgc tcgatccact gattcgtaaa gatatgcagg atgagcttct tgatcttcac 321661 gataatgtcg gaaaaacaat tatctttatt acgcatgact tggacgaagc gttgcggatc 321721 ggcgacagaa ttgtcctaat gaaggacggc aacatcgttc aaatcggcac gcctgaagaa 321781 atcctgatga atccatctaa cgaatatgtt gagaaattcg tcgaagatgt tgatttgtct 321841 aaagtcctca cagcaggcca cattatgaaa cgcgctgaaa cagtgcggat tgataaaggg 321901 cctcgcgtag cattgacact gatgaaaaac cttggaattt cttcaattta tgcagtggat 321961 aaacaaaaga aattattagg tgttatctat gcgtctgatg cgaaaaaagc ggctgagtct 322021 gatttgtcac ttcaagacat cttgaataca gaatttacga ctgtaccaga gaatacgtat 322081 ctgactgaga tttttgacgt tgtgtccgat gcgaatattc caattgcggt tgtggatgag 322141 aagcaaagaa tgaaaggaat tgtcgtaaga ggcgcgctga ttggcgcact tgccggcaat 322201 aacgagtata tcaatgctga aggcactaac gaacaaacac aagatccttc tgcacaggag 322261 gtgaaataag atggatagac tgcctagaat acctttagca gatattattg accgttttgt 322321 tgactggatt acgatgacgt ttggcggatt cttcgacgga atcgctaacg gattggccgc 322381 ttttgtaaat ggaattgtca ccggtcttgg atttattcca tctattttgt taacgattat 322441 tttcgccgca cttgcgtggt ggatcagtac aaggggaatt gcgttattta cgttgattgg 322501 attcctcctg atcgattatt taggatattg ggacccaatg ctgcaaacat tggcgcttgt 322561 tttgacatct gtgattattt cgattgtggt cggggttccg atcggaattt gggcgtctca 322621 gaaagaaacg gttcgccgta ttgtaacgcc aattcttgat ttaatgcaga caatgcctgc 322681 tttcgtatat ctattgccgg cgattttctt ctttaacatc ggtgttgtgc cgggtgttgt 322741 tgcatctgtt atcttcgcga tgccgccgac aatccgcatg actgttctcg gtattaaaca 322801 agtgccggcg gatttgattg aagcgactga ggcattcggt tctacaacag ctcagcgttt 322861 gtttaaagtt cagctcccgc ttgcgacaaa aacgattttg gccgggatca accagagcat 322921 catgcttgcg ttatcaatgg ttgttatcgc cgcaatggtc ggtgcaccgg gacttggttc 322981 tgaagtatac agtgccgtta cacagctgaa aaccggggtc ggagtagagg ccggtatcgc 323041 catcgttatc gttgccatta ccctggaccg tattactcaa aatattaaag tgaagaagaa 323101 aagcaggggg aatgcctgat gcttaaaaaa atcataggca tcggcgtttc cgccatgctg 323161 gcgctctcac ttgcggcttg cggttcagaa aacgatgaaa atgcatccgc agcagaacaa 323221 gtgaataaga ccatcatcgg gattgacccc ggttcaggga ttatgtccct gactgacaaa 323281 gcgatgaagg attatgacct gaatgactgg acattgattt cagcgtcaag tgctgcgatg 323341 accgctacgc ttaaaaagtc atacgaccgt aagaaaccga ttatcattac aggatggaca 323401 ccgcactgga tgttctccag atataagctg aaatatctcg atgatccgaa acaatcttat 323461 ggcagcgcag aggaaatcca tacgatcaca cgcaaaggct tcagcaaaga gcagccgaat 323521 gccgcaaagc ttctgagcca gtttaaatgg acgcaggacg aaatgggcga aatcatgatc 323581 aaggtggaag aaggcgagaa acctgccaaa gttgctgctg agtacgtcaa taaacacaag 323641 gatcagattg ccgaatggac aaaaggcgtt caaaaggtga agggagacaa aatcaacctt 323701 gcctatgtgg cgtgggacag tgagattgca agtacaaacg tcataggcaa agtcttagaa 323761 gacttgggct atgaggtaac acttactcag gtagaggctg ggccgatgtg gactgcaatt 323821 gcgacgggaa gtgcggatgc atccctttcc gcatggctgc cgaataccca taaagcatac 323881 gccgctaaat ataaaggcaa atatgatgat attggcacca gtatgactgg tgtgaagatg 323941 gggcttgttg ttcctcaata tatgaaaaat gtcaactcaa ttgaagattt gaagaagtaa 324001 tcaaaaaagc agcctgtgtc aggctgcttt ttttgcgtta agaagcgtta gcggcagcaa 324061 gtgattccgc cttctgaaat gttttgagca cggcgttcgc caaaatatga atgccggtaa 324121 acatcgcatt tctgtcaaag gtcatgtgcg gatgatggag ccccggctgg agcccgcagc 324181 ctagtccgag catcgttgtt ttcagattcg gcaccttcac ggcgtaaaaa tggaaatcct 324241 cgccgccggt ggtgacaagc gggtcatcaa gccgctcagc cccgatgatt tccgtaatgg 324301 cttctgccat gatcgcttca gcttctttat tttgtgttgc cgcaggaagg ctgtgttctt 324361 tgtgcagctc gatctttgcg ccaaatgcag cggcggccgc ttcacaggct ctttctgttt 324421 cggcgattaa tgcctccatg gcttcattgg tctgtgcgcg caaatcaagg ctgaacgatg 324481 cttttcctgg aatgatgtta gagctttcac cgccggcttg cagttttgtc attttgacgg 324541 tatgcgggat ttgcgggtca atatgaatga gtccgagctt gtgtacaaga aatgccgcaa 324601 tttcaatgct gtttttcccg aggtgcggac gggcgccatg agcctcttcc ccgatgatcg 324661 ttccctcaat gtgctggctt gatccgtgca gaatagaagg agcgcagcgg ccgttctgtg 324721 tttcctggat cggacggacg tgaacgccat acaaatagtc gatatcatca agcacgcctt 324781 cttctatcat tttcaaggcg ccgccgcctt tttcttctgc cggctgaaag ataaaacgga 324841 ttgtgccctt cggaagctca ggttgttttt ttagcagcat taacgtgccc aatgccattg 324901 tcatatgtga atcgtgtccg caggaatggt tggcgcgaaa tgtgccgtta acctcctgcc 324961 acagcgcgtc aatatcagcg cgtaccgcta caacaggtga gcctgagccg atttcgccga 325021 caaccccggt gcagtctgaa aacgtgcgcg tccggcaccc taaatcctca agcttttgtt 325081 tcaaaaatga agttgtctca tattccttcc agctgacttc agggttcgcg tgcagatgct 325141 cgaagatgtc cataatggtt tgtttcattt cttctgaaag cttttgcatg gtaagaaata 325201 cctccttcta tcagaatgaa tttttacctt ctttacttta tttatattga aacaggaaga 325261 taggctgtat ataatatagc acatattgct actattcaga ataattaata ttttcaaaca 325321 gaggggatgg atcgaaatat gagtatgcca gcagccgaaa cacagcctaa gaaaaaacgt 325381 atgacattta aaatgcctga cgcctatgtc ctcttattta tgattgcttt catttgcgca 325441 atcgcttcat atattgtgcc ggcaggtgaa tttgaccgcg tgacaaaggg ggatgtcacg 325501 accgctgttc cgggaagcta tcattcaatt gaacagtctc cggtcagatt gatcagcttt 325561 tttacttctc tacaggatgg aatggttgga tcagcaccca tcatctttct gattttattc 325621 acaggcggca ccattgctat tctagaaaaa acgggtgcca tcaatggcct gatttacaat 325681 gtcatcagca aattccgcac aaagcaatta ttatttattt gtattgtcgg cgcattgttc 325741 tccattctcg gaacaaccgg gattgtcgtg aattcagtta tcggttttat ccccatcggc 325801 ctcattgtgg cacgatcctt aaaatgggac gcagtcgcgg gagccgctgt tatatacatc 325861 ggctgctacg ctggatttaa ctccaccata ttatcaccgt caccgctcgg tttatcacaa 325921 tcaatcgcgg agctccctct tttctcagga atcggcctgc gagttgtgat atacatatgc 325981 tttttgctgt cttctattat ttatatctat ttgtatacga gaaaattaaa aaaatcaaaa 326041 gatgccagtg tgttaggaac agattggttc cctgcggcag gaatgggcga agccggtaaa 326101 gaagaagatc agtcagtgcc gtttaccgtt cgccataagc tgattttggc tgtggcggga 326161 ctctcacttg tcggattttt atacggcgct ttgaagcttg gctggtcaga ttcccaaatg 326221 gctgcgacat ttatttttat ttctgtcctt gccggtttaa taggcgggct tgcggcgaac 326281 gatattgcca aaaccttcat tacgggctgc caaagtcttg tatacggggc gctgattgtc 326341 gggatggcac gaagcatttc cgttatcctt gaaaatggaa agcttctcga tactgtcgtc 326401 aatgctttgg cttcactttt ggatggattc agcccgattg ctggggcaat cggcatgtat 326461 atcgccagtg cgctgcttca ttttctcatc tcttcaggtt ctggcgaagc cgttgtattt 326521 attccaatcc tggcgccgct cgctgatttg atgggaatca cgagacaggt tgcggttgaa 326581 gcggttatgc ttggagaagg ggtcgtcaac tgtgtgaacc cgacatccgg cgttctcatg 326641 gcggtgcttg ccgccagcgg tattccgtat gtcaagtggc tgcggtttat ggtgccgctt 326701 gctctgattt ggttcttgat cgggcttgtc tttatcgtga tcggagtcat gatcaattgg 326761 gggccgtttt aacgattgct gcccgccggc ttgtacggcg ggcttttgag ttattcattg 326821 cagaagcgca ggctgttatt gtaacatgta agccataagc cattcgtaaa agtgcgggag 326881 gaaggtcatg aataatctgc gtaatagact ttcaggcgtg aatgggaaaa ataagagagt 326941 aaaagaaaaa gaacaaaaaa tctggtcgga gattgggatg atagcgggag catttgcgct 327001 gcttgatgtg atcatccgcg gcattatgtt tgaatttccg tttaaagaat gggctgcaag 327061 ccttgtgttt ttgttcatca ttatcttata ttactgcatc agggctgcgg catccggaat 327121 gctcatgccg agaatagaca ccaaagaaga actgcaaaaa cgggtgaagc agcagcgaat 327181 agaatcaatt gcggtcgcct ttgcggtagt ggtgcttacg atgtacgaca gggggattcc 327241 ccatacattc ttcgcttggc tgaaaatgat tcttcttttt atcgtctgcg gcggcgttct 327301 gtttctgctt cggtatgtga ttgtgaagct ggcttacaga agagcggtaa aagaagaaat 327361 aaaaaagaaa tcatcttttt tgtttggaaa gcgagggaag cgttcacagt ttcgggcagc 327421 tttttttata ggaacattga tttgtattca ctctgccaag ttgttttgat agagtgattg 327481 tgataatttt aaatgtaagc gttaacaaaa ttctccagtc ttcacatcgg tttgaaagga 327541 ggaagcggaa gaatgaagta agagggattt ttgactccga agtaagtctt caaaaaatca 327601 aataaggagt gtcaagaatg tttgcaaaac gattcaaaac ctctttactg ccgttattcg 327661 ctggattttt attgctgttt catttggttc tggcaggacc ggcggctgcg agtgctgaaa 327721 cggcgaacaa atcgaatgag cttacagcac cgtcgatcaa aagcggaacc attcttcatg 327781 catggaattg gtcgttcaat acgttaaaac acaatatgaa ggatattcat gatgcaggat 327841 atacagccat tcagacatct ccgattaacc aagtaaagga agggaatcaa ggagataaaa 327901 gcatgtcgaa ctggtactgg ctgtatcagc cgacatcgta tcaaattggc aaccgttact 327961 taggtactga acaagaattt aaagaaatgt gtgcagccgc tgaagaatat ggcataaagg 328021 tcattgttga cgcggtcatc aatcatacca ccagtgatta tgccgcgatt tccaatgagg 328081 ttaagagtat tccaaactgg acacatggaa acacacaaat taaaaactgg tctgatcgat 328141 gggatgtcac gcagaattca ttgctcgggc tgtatgactg gaatacacaa aatacacaag 328201 tacagtccta tctgaaacgg ttcttagaca gggcattgaa tgacggggca gacggttttc 328261 gatttgatgc cgccaaacat atagagcttc cagatgatgg cagttacggc agtcaatttt 328321 ggccgaatat cacaaataca tctgcagagt tccaatacgg agaaatcctg caggatagtg 328381 cctccagaga tgctgcatat gcgaattata tggatgtgac agcgtctaac tatgggcatt 328441 ccataaggtc cgctttaaag aatcgtaatc tgggcgtgtc gaatatctcc cactatgcat 328501 ctgatgtgtc tgcggacaag ctagtgacat gggtagagtc gcatgatacg tatgccaatg 328561 atgatgaaga gtcgacatgg atgagcgatg atgatatccg tttaggctgg gcggtgatag 328621 cttctcgttc aggcagtacg cctcttttct tttccagacc tgagggaggc ggaaatggtg 328681 tgaggttccc ggggaaaagc caaataggcg atcgcgggag tgctttattt gaagatcagg 328741 ctatcactgc ggtcaataga tttcacaatg tgatggctgg acagcctgag gaactctcga 328801 acccgaatgg aaacaaccag atatttatga atcagcgcgg ctcacatggc gttgtgctgg 328861 caaatgcagg ttcatcctct gtctctatca atacggcaac aaaattgcct gatggcaggt 328921 atgacaataa agctggagcg ggttcatttc aagtgaacga tggtaaactg acaggcacga 328981 tcaatgccag gtctgtagct gtgctttatc ctgatgatat tgcaaaagcg cctcatgttt 329041 tccttgagaa ttacaaaaca ggtgtaacac attctttcaa tgatcaactg acgattacct 329101 tgcgtgcaga tgcgaataca acaaaagccg tttatcaaat caataatgga ccagagacgg 329161 cgtttaagga tggagatcaa ttcacaatcg gaaaaggaga tccatttggc aaaacataca 329221 ccatcatgtt aaaaggaacg aacagtgatg gtgtaacgag gaccgagaaa tacagttttg 329281 ttaaaagaga tccagcgtcg gccaaaacca tcggctatca aaatccgaat cattggagcc 329341 aggtaaatgc ttatatctat aaacatgatg ggagccgagt aattgaattg accggatctt 329401 ggcctggaaa accaatgact aaaaatgcag acggaattta cacgctgacg ctgcctgcgg 329461 acacggatac aaccaacgca aaagtgattt ttaataatgg cagcgcccaa gtgcccggtc 329521 agaatcagcc tggctttgat tacgtgctaa atggtttata taatgactcg ggcttaagcg 329581 gttctcttcc ccattgaggg caaggctaga cgggacttac cgaaagaaac catcaatgat 329641 ggtttctttt ttgttcataa atcagacaaa acttttctct tgcaaaagtt tgtgaagtgt 329701 tgcacaatat aaatgtgaaa tacttcacaa acaaaaagac atcaaagaga aacataccct 329761 ggaaggatga ttaatgatga acaaacatgt aaataaagta gctttaatcg gagcgggttt 329821 tgttggaagc agttatgcat ttgcgttaat taaccaagga atcacagatg agcttgtggt 329881 cattgatgta aataaagaaa aagcaatggg cgatgtgatg gatttaaacc acggaaaggc 329941 gtttgcgcca caaccggtca aaacatctta cggaacatat gaagactgca aggatgctga 330001 tattgtctgc atttgcgccg gagcaaacca aaaacctggt gagacacgcc ttgaattagt 330061 agaaaagaac ttgaagattt tcaaaggcat cgttagtgaa gtcatggcga gcggatttga 330121 cggcattttc ttagtcgcga caaatccggt tgatatcctg acttacgcaa catggaaatt 330181 cagcggcctg ccaaaagagc gggtgattgg aagcggcaca acacttgatt ctgcgagatt 330241 ccgtttcatg ctgagcgaat actttggcgc agcgcctcaa aacgtacacg cgcatattat 330301 cggagagcac ggcgacacag agcttcctgt ttggagccac gcgaatgtcg gcggtgtgcc 330361 ggtcagtgaa ctcgttgaga aaaacgatgc gtacaaacaa gaggagctgg accaaattgt 330421 agatgatgtg aaaaacgcag cttaccatat cattgagaaa aaaggcgcga cttattatgg 330481 ggttgcgatg agtcttgctc gcattacaaa agccattctt cataatgaaa acagcatatt 330541 aactgtcagc acatatttgg acgggcaata cggtgcagat gacgtgtaca tcggtgtgcc 330601 ggctgtcgtg aatcgcggag ggatcgcagg tatcactgag ctgaacttaa atgagaaaga 330661 aaaagaacag ttccttcaca gcgccggcgt ccttaaaaac attttaaaac ctcattttgc 330721 agaacaaaaa gtcaactaac cgcaacttta gagtaaaggg ctgattgtca atgtgggagc 330781 agttgtatga tccgtttgga aacgagtatg tgagcgcact tgtggcgctc actccgattc 330841 tcttttttct tttggcttta actgttttga aaatgaaagg cattcttgcg gcatttctta 330901 ccctagccgt cagtttcttc gtctccgttt gggcatttca tatgccggtt gaaaaagcga 330961 tttcttctgt tttgttagga atcgggagcg ggctgtggcc cattggctac atcgtcctga 331021 tggcggtgtg gctgtataaa atcgccgtga aaaccgggaa atttaccatt attcggtcca 331081 gcattgccgg catttcgcct gaccaacgat tacagctatt attaattggt ttttgtttta 331141 acgcgttttt agaaggcgcg gccggttttg gtgttccgat tgcgattagt gcggcgctgc 331201 tcgtcgaact tggttttaaa ccgttaaaag cggcggcgct ctgcttgatt gcaaacgctg 331261 cctccggagc ctttggggcg attgggattc ctgtcatcac aggggcgcag attggtgatt 331321 tgtctgctct tgagctgtct cggacattaa tgtggacact gccgatgatc tcatttttaa 331381 taccattcct gcttgtattc ttattagacc gaatgaaagg aatcaaacag acatggcccg 331441 ctcttctggt tgtgagcggt gggtatacag cggttcagac actgacaatg gcggtgctcg 331501 ggccggaatt agcaaacatt ttggcggcct tattcagcat gggcgggctt gccctcttcc 331561 tccgcaaatg gcagccgaaa gagatttacc gcgaggaagg ggccggcgat gctggtgaga 331621 aaaaggcata ccgtgccgct gacattgcga aagcgtggtc tcctttctac attttaactg 331681 cggcgatcac catctggagc cttcctgcct tcaaagcgct tttccaagaa ggcgggctgt 331741 tatatcaatc aacgctcctg ttcaaaatgc cttttctgca tcagcaaatt atgaaaatgc 331801 cgccgattgc gccatctgcc atgccgttag atgcagtctt taaagttgat ctgctgtcag 331861 cgactggtac agcgatttta gcggcggtca tcgtgacagg gctgttcagc aaaaagttct 331921 cctctcggga tgcctttgct tccttgaagg agacgggaaa agagctgtgg gtgccgatta 331981 tgacgatctg cttcgtgatg gggtttgcca atctggccaa cttcgcaggg ctcagctctt 332041 caattgggtt agcattggcg aaaacaggag acctgttccc gtttgtcagt cctgttctcg 332101 gctggattgg cgtgttcatc accggttctg ttgtcagcaa taatgctttg ttcggccatt 332161 tgcaggttgt cacgggagcg cagatcggtg cgggttcaga tttgctgtta gccgcaaata 332221 cggcgggcgg tgtcatggcg aaacttgttt ctcctcaatc tatcgccatc gctgccgcag 332281 cggtcggcca aacaggcaag gaatctaaac tgtttaaaag gacagtggcg tacagcctga 332341 ttctgttatt gatcatttgt atatggacgt ttattcttgc aagattagga gtgtaataga 332401 aaaaagcagt acatgcccag catgtactgc tttttttatg ttaatttgct ttctttgtca 332461 tttcggctgt tgttttcact ctggcttttc ccataaataa aatggtaacc gccgcgagga 332521 caattggaat caaagcgagc aaaaagacat acgtgatact tgatgacatc gcgtcaataa 332581 tgcgattcag gatcgcatca ggaatctggg aacgtgttcc cgcttggaat atctcctgcg 332641 ggtcgccaat attttgcgca gcgcctgatc ccgctgagcc tttcataccg ctgaaggcgt 332701 cattcagctt gtttgtgaat acgtttgttt gcaccgttcc gaaaatggtg acacctaagg 332761 tcatgccaaa tgatcgcaaa aatgaatttg tagagtttgc cgttccccga aagcgaggtt 332821 caagatcatt catcgatgcc gccggcagca gggagaagtt aaagcctaca ccaaagcctg 332881 aaatcatcat aaagactgtc agccataccc gtgctgtgtc aggcgtcata ttggaaagaa 332941 gcagcatgcc gataaagaaa gctataacag atatcagcat caaattgcgg aagcttgcct 333001 tcgtttggaa gatcccgccg atcatgcttc cgatgactga tccaatcatc atcggcgtca 333061 gaatgaagcc cgcgcttgtc gccgagctgc cgtagaccgc ctgaacgaaa atcggaataa 333121 ataccgctaa aataataaat gttccgccat acaggaaagc gagaatctgt gctgtggcaa 333181 acaagcggtt cttaaacatc cagaaagaaa taatcggctc ttctgctttt ctctccacaa 333241 taaaaaaggc aatgaagaaa acggcgaata caataaacag cccgatgatc tgaatggagt 333301 tccaatcgta tgttttgccg ccaagctcaa gggcgaacat caggcataca atggatacga 333361 ctaaggtaat cgcgccgccc cagtctattt tctgctttct gtgctccaga gattctttgt 333421 agtagcgaat aatgaaaaac aatgacaatg cgccgatcgg cacattgatg taaaacaccc 333481 agtgccagct gatcgaatct gtaatgatcg cgcctaagag cggaccaaga acactggata 333541 atccaaatac agcaccgaac atgccggaca tttttccgcg tttttccggc ggaaacaaat 333601 caaagataat ggtaaaggca atcggcagga gcgcgccgcc tccgatccct tgaatggccc 333661 ggaagatgat cagctgattc atcgtctggg caatcccgca taaagcagaa ccgattaaga 333721 aaaaaataag tccaaacagg aaaaaacgtt ttcggccgta catatcggaa agcttgccgt 333781 aaatcggcat gccagccata accgccacca tataggatgc cgtcacccag gcaaatttat 333841 cgaagcttcc aagatcggct acgatattgc ccatcgcggt ggcaacaatc gtattgtcca 333901 ttgcagacat caagatgccc agcaggagac cgaggaccac aaatttggtg gaagcctgtt 333961 ttgctgttgt tgtgtccatt tgttctacct cctcttactt ttctatgtaa gttctgatat 334021 catgataata gtttgattgt tgaatatctc gattatcaag ataaactcga ttttataggg 334081 aggactgtca gttgtcaaca agaaattcca gaagtgagtt ggaaaagact gctgttcagc 334141 tttttcgaaa actgggcaca agaacggttc tgtttcatca ggcagccgct caagctctcg 334201 gtctgtttcc caccgatttg aaatcagctg acattttaaa tgaagcaggg ccgatgacgg 334261 ccggagagct ggggaaaaaa accggcctca gcacgggttc cgtcacggcg cttgttgacc 334321 ggctggaaaa agcggggtat gtggctcgtg aaaaggaccc gaacgatcgc aggagagtcg 334381 taatcgtccc tttgactgct tcgaaaaaac atataaagga tttgttccgt cctctgtctg 334441 agtcaacgat ggatttgtgc cgcgaatata cggaagagga gctggaactc attttcagtt 334501 ttgtaggcaa agctgccgat attatggagg aagagcttga acgtctgaaa cagtaagtga 334561 atttgtgcat agcttggccc gttcccgaat aaattgtaca agttacataa gagaagggag 334621 tacgggccgg tgaacatttt tttgagctat attgtgctgg gactgtcctt gtctgcgcct 334681 gtggggccag tgaatgcggc gcaaatagac aaaggaatta aaaacggttt ttggcatgca 334741 tggattttcg gtttaggcgc catgacagcg gatgggctgt acatgctttt tatctatttc 334801 gggctgtcgc agttcttgac cgctccattt gtgaaaacgt ttttgtggct gttcggcttt 334861 tttgtcctga cctataccgg aattgaaacg ctgaaaaacg tcagagaacc gatggatgtg 334921 cgaagctcgc gggggaaacc gtcatacagg aaaacattcg catcgggttt tctcatttca 334981 ttgtcaaacc cattgagcat ccttttttgg cttggaattt acggaagcat tcttgcgaaa 335041 acagcagagg cctacaatat gaatcagctt ctaatctata gctccggcat catgatcggc 335101 attttaatct gggatttctg catggctatc acagccagta cgttcagaaa cctgcttcat 335161 gaaaagctat tgagaggatt gaccggaatc gccggtgtat ccctccttgt gtttggcttt 335221 tactttggtt atcagggcat caaacagtta ttgggctgat tcatgaagga cagtcacctg 335281 ccgcttccag ttttaatata gtatccagat gatactggag gtggatcaat ggtgaatggg 335341 atttacacca aaagttttct ggaacgtatt caggaagagc ttcctgaatg gcaaagaatc 335401 gcttttgagc tgctggcaga aactctgggg gacgacgcgg atacatttcc gtgcattccc 335461 ggacgccagg cgtttctgac tgatcagctt cggattgctt ttgccggaga tccgcgggaa 335521 aaccgcacag cggaggaact ggctccgttg cttgcggagt acggcaagat atcgcgggac 335581 acgggaaaat acgcatccct cgttgtgttg tttgatacac cggaagattt ggcggagcat 335641 tattcgattg aagcgtatga agagctgttt tggcgctttt taaatagact gagtcatcaa 335701 gacgaaaaag aatggccgga agacattccg gccgatcctg agcattataa atgggagttt 335761 tgttttgacg gcgagccgta tttcattctg tgcgctacac cggggcacga ggcaagaaga 335821 agccggagct ttcctttttt tatggtcacg tttcagccaa ggtgggtgtt tgatgaccta 335881 aatggatcaa ctgcatttgg ccgtaacatg agcaggctga tccgatctcg tttagaggcc 335941 tatgatcagg ctccgattca cccgcaatta ggctggtacg gaggaaaaga taatcgtgaa 336001 tggaagcagt atttcctccg tgatgacgaa aaacaggtat cgaagtgccc gttttcttat 336061 ttaaagaaca tgttcaacaa aatgaaataa atcaaggact ggcagggcga tctttatgac 336121 cctgcttttt ttgatagatc atggtaacga tggcgataat cacgagaaaa cctatgctga 336181 cgaaaaaacc gggccggctt gatttttcaa acaatgtacc ggacacagct gcagcaatca 336241 gaaccatcgc taaataaatt tgcgtttttc ccatgccctc gggatcagtc agctttttgc 336301 tggagaacag gataaacagc caagtgtata aaagcataag ccccgcagct gttgtcatat 336361 gctcataaat gtttttaggc agcactaacg acaaaataat ggagaggaca agccccgcaa 336421 acgtcagccc aagtgccggc cagcatattt ttttgccttc ctttagagta aagcatttcg 336481 gcgcgtcgcc gtcatcagcc attgtacaaa gcaatgtcgt aaccgcaaat agcgaagcga 336541 caagggtcga gaaccctgcg atgatgaaaa tcccgttaaa tatatcaagg atgatctcaa 336601 ggttatatcc ttttaatgac gtaatgaacg gactgtcctg ttcagtaaac gtgtgtaacg 336661 gaaccaaaag cagagcaagc ccgattgaaa tgatataaat aatcgccagc gtcgccagca 336721 tcagtttccc tgatttagac gcttcctcag gtttttttaa gtgaaccgcc atcagcccca 336781 tgacctcaat tccgccaaaa gcgtaaaacg cgtagattaa acctgtccac agccccatgg 336841 cgccgtatgg gaaaaactca ctcgtcttat ttggaacatg tatgccatga tttccgccgg 336901 acaggatacc gcataaagcc aggatggcaa tgacaataaa cataaaaata gcagctgttt 336961 taatgactgc cagcacgttt tctgtttttt caaagacgga caggccggtg aaaataataa 337021 ggagcccaag tactgcgtag attgaggcaa acacccatag cggcacttga ggaaaccaat 337081 gcttcgtaaa gagcgaaatg gctgtcagct ggcttccggt aatcagcatt tctgatgtcc 337141 agtacaccca gccgttgctg aagcctgccc atttgccgaa tgcttttcgg gcatacgcac 337201 aaaacgagcc cttttccggc tgcttcgccg atagcttggc gagctgttca aagacaaaat 337261 acgtaccgat ccctgcgatc agaaatgaaa ggagaacgga aaaaccgctt tttacaattg 337321 cgatgctgga accgagaaag aagcctgttc caatcgtgca gccgactccg atcagtgaca 337381 gctgccacca agccagattc ccttttggct ggtctttttt tgtttggctc attatttatt 337441 caaccccttt tatctaaggt tagattgtga tctgtccaaa gcttatatac atcggatttt 337501 tgcctctttt tacatggaga aggaagcaga cgctcatact aatgaaaaaa ggagcaaacc 337561 aatgacacag caatatattg tggagccgaa aaaagggctt gggctgaagc tgaaaaaggg 337621 gcagatttta aaggtggttg atgtagaagg gcagcaggtg gctgattttg tcgcatacca 337681 tgccaaggat ttttatgaac accttgatca gggagcgacg atagacgcca atcactccat 337741 tcatgtgaag gtcaacgacc atctctactc caacctgtat aagccgatgt taaccctgat 337801 tgaagatacg gtcggcaagc atgatctgct gttgcccgcc tgccgtcctg atatgaacag 337861 gctcttatat gggaagcaaa aggatgagtt tcaggatacg tgctatgaca atatgaaccg 337921 tgcgcttgag cagtttggcg taccgaagcc ccacatgcat tacccatttg cgatttttat 337981 gaatactgtc cttgatgaga aagggaatct gtctgtggaa acgccgcttt cgaatgccgg 338041 agattatgta aggctcaggg cggagatgga tttaattgtc gcgttttctt cctgcccgat 338101 tgaaaaaggg aaatgcaatg gcgacagtgt gacatccata cgggttgaag tcagctgatc 338161 tctcttgttc acagtgaatg aagacctgtg ctatatttaa tagggataca taacagtcat 338221 gattcatttt cattgattta gggaaatgat cagtaataag ggaaaatgta caggaggaat 338281 gattgggatg agcatgcagg aaaagattat gcgtgagtta catgtgaagc cctcaattga 338341 tccaaagcaa gaaattgagg accgagtcaa ttttttaaaa caatatgtaa agaaaaccgg 338401 tgctaaaggc tttgtattgg gaatcagcgg gggccaggat tcaacacttg cgggaagact 338461 cgctcagctt gcggtggaga gcattcgcga ggagggcgga gacgctcaat ttatcgcggt 338521 ccgtcttccg catggcacac agcaggatga agacgatgcc cagcttgctt tgaagtttat 338581 taagccggat aaatcatgga agtttgatat taaatcgaca gtcagcgctt tttctgatca 338641 gtatcagcag gaaacaggcg atcagctgac ggactttaat aaaggaaacg taaaagcaag 338701 aacaagaatg atcgcgcaat acgcgatcgg cggccaggaa ggtcttcttg tgttaggaac 338761 agaccatgct gctgaagcag tgactggttt ctttacgaag tacggtgacg gcggagcaga 338821 cctcctgccg ctgacaggct tgacgaagcg ccagggaaga accttgctga aagagctggg 338881 tgcaccggaa cgcttatact taaaagaacc gactgccgat ctgctcgacg aaaaaccgca 338941 gcagtcggat gaaacagagc ttggcatttc ctacgacgag attgacgatt atctcgaagg 339001 aaaagaagta tcagcgaaag tatcagaagc gctggaaaaa cgctacagca tgactgaaca 339061 taaacgccag gttccggcgt ctatgtttga tgactggtgg aaataagttg aagaaagccc 339121 gctctcggag cgggcttttg tcgtgtacag aagctttatt tgatgcggat atgattcagc 339181 tttaccatta atctgtcggc gaaccttcgg aggctgcctc ttgtatcagg atctaatggg 339241 agttcggctc tcgcggcaat gttctctgcc acatcctgaa tcgacaggtt gtctgtttga 339301 atgtggtcct caaaaatggg tgatgataat ccttcaacac agcggtcaat ttgtttggcg 339361 gcccatgagt tttttccttc tgctctggtg cgcagccttt ttaacaaggt ttcctttgaa 339421 gccattagtg taaagtggtg aacgatcctg ccttcctgtc tgagcctgcc gatgatctca 339481 ttgaagtatt cagggtgtac aatcgtcata ggcacaataa ggatgccgcg gtatgtatct 339541 gtcagagaag ctagcaaact gtaattgaac gcccgccata aaggatagct ttgaaaatcg 339601 tcctttgcga tctcctgcgg caccatggag cgcagcgcaa aacccatttt ctcgggatca 339661 tacacgtaag atgggttcag ccttctgtgc agttcgaagg ctgtttgtgt ttttcccgaa 339721 ccgaatgccc cgtttatcca aatgatcatc gccatttctc ccttcctatt tatcatacag 339781 aaaaagaccc ttccatcgaa gagtcagctg gaaaaacaat aaaggcggaa ggttttaacg 339841 cttttttgcg tcgaagtatt aaaatacctg cagaaatgtt gtacaatgaa tgtcattcag 339901 gcaaaaatgg ctacaacaaa gcgcactata agcttgaccg gtaaagccgg tatctatata 339961 aatattcgct aaataagcat ataatgaata tataatttca ttccttagga ggatttcgcc 340021 gaagatgaac gctaaacgag ccatcccagt aagagaaaga aatatcgtcc tgatcggatt 340081 catgggtgta ggaaaaacaa caatcggcca attggtcgct aaaaaattat atagagattt 340141 tattgatatt gaccagcaga tcgaaaagga tttcaatatg tcaattcctg agatatttga 340201 gaaaaaggga gaagactttt tccggaaaac ggagaaggaa tatattttag acatctgcca 340261 tcataaacga ttcaaaatcg tatctctggg cgggggatct tttaaacaag aagaaatcag 340321 aaattgctgt ctggaaaact gtctcgtgct tcatctggac ctgtcatggg agaactggaa 340381 gcagcgcgcg gatttattga tcgaaagccg ccctgtactg cataaccgtt caatggatga 340441 aatggaacag ctgtttaacg aaagaaaagt catttatgac aagcacaatt caaaagtggc 340501 aacagacaac ctttccccgg aagaggttgc cgattacatt gttgagacat taaaaattgg 340561 ctgggatctt tatcagccga tgtaaaaagc cgtgcgcagc gcacggcttt ttttatcgtt 340621 ttatcccttg tatcaaaatc gcttttaaac aaaaggagat gggctgtccg ttttggttca 340681 atgtaataca gaacgtgtcg cgtgcttcgt ctgatgcgtg attcaagtgg gtaatgattt 340741 gtttttctcg gtcagcgggg gttccgcctc gtttgatcca gctatcgtat tgaatcggca 340801 agttccactt ttggatgtct tgataggcca gttgattggc gctgaacatc gcctgccatt 340861 ctgataatga gctttcacga acatgggaag ggtctcgaag ccggttcaaa tgattgacaa 340921 actcatcaag aacgggatct tcaggcgcgt aatgatcaac taagagaaaa cgtccgtcct 340981 gttttagtac gcgtgcaacc tctctgacag ctttgcggac atctgaaaaa tggtgggctg 341041 cgtatcggca ggtgatgatg tcaaatgaat cgtcggggaa ggggagtgac tctgccgttc 341101 cttgctgaaa gcgtacgttt tcaactcctt tttcttgcgc gaaggaggac gcaacctcaa 341161 ccatctcttt cgttgcatca acaccgatgc actcctgtac ataaggagaa aatgccagcg 341221 ccgtatggcc ggcgcccgct cctatatcca gcactcgatg ctctgcccgg cattccgctg 341281 ttttgatcat caaccccaaa tcttccccct cggcaaatac cttttcatcc cgatacatct 341341 cggcgttttt agaaaacggt gtttcatttg tcatttgaac cagctccttc ttttcgtaaa 341401 tgatgatatg gattatgtta gcaatttctg ttatgattcg tccaagatat aaaaatgatg 341461 aaaatgatag gttcaaccta tggaggctga aatggatatt aaagtgatgg aatatgcagc 341521 ggaaattgcc cggcgccaaa gctttacaaa ggcggcggaa catcttcata tcgcacagcc 341581 gtctctcagc cagcaaatca aaaagcttga ggctgagctg gggcttaccc tttttcacag 341641 atcccatggc tctgttacac tgacacctca cggcaggcgt ttcattgaaa aagccgagga 341701 catcattcgt tccagagatg atttgcttcg ggaaatgcag gagcgatcac agggaatcgg 341761 tcataaatta tccatcggga ttcctgctgt aacagggaga tatctctttc ctccgctgct 341821 gaagcagttt ttggcgcgct atcctcatgt ggaggttcag cttgttgaaa aagatccggt 341881 ttcattagag aagatgacgg caaagggaga agttgacctt tctgttttat ccttgcccat 341941 cgaggatgaa cggctctcca ttacaccctt gctcacggaa ccggttgttc tcgcggtgcc 342001 gaaggaaaaa caaaggtgga tgccgccgga attggtcgcg ctgattgaga aagcgctgga 342061 agaagatgag ggacgccagc cgtgtgtgcc gattgacatg gtaaggaacg tgccctttat 342121 tctgttaaaa gaaggcttcg gctttcgcag gacagttctc gatctctgtg cggaaagcgg 342181 ctttaagccg aatgctgcct ttaagacgag ccatattgaa accgcccaat ctcttgtggc 342241 taacggatta ggtgtgacaa tggcaccgaa tatggtcaga agggataaag atccgggtgt 342301 gatctattta tcgattcaat ccgcgccatc acgaaccctc gtctttgtct ttttaaagaa 342361 ccgctatgtc agtctgacgg cccaggcctt tatggaacta agccgggaaa gtcttaaaca 342421 aacgtttgat gaaggctgtc tgggaaacaa agatgaaaat atttagaaaa caaagacgaa 342481 acgtggtagt ataggaatac aaactaaatc ttataaaaca aaggggaata atcggaaatg 342541 caactattcg atctgccgct cgaccaattg caaacatata agcctgaaaa aacagcaccg 342601 aaagattttt ctgagttttg gaaattgtct ttggaggaac ttgcaaaagt ccaagcagaa 342661 cctgatttac agccggttga ctatcctgct gacggagtaa aagtgtaccg tctcacatat 342721 aaaagcttcg gaaacgcccg cattaccgga tggtacgcgg tgcctgacaa ggaaggcccg 342781 catccggcga tcgtgaaata tcatggctac aatgcaagct atgatggtga gattcatgaa 342841 atggtaaact gggcactcca tggctacgcc acattcggca tgcttgtccg cggccagcag 342901 agcagcgagg atacgagtat ttcaccgcac ggtcacgctt tgggctggat gacgaaagga 342961 attcttgata aagatacata ctattaccgc ggtgtttatt tggacgccgt ccgcgcgctt 343021 gaggtcatca gcagcttcga cgaggttgac gaaacaagga tcggtgtgac aggaggaagc 343081 caaggcggag gtttaaccat tgccgcagca gcgctgtcag acattccaaa agccgcggtt 343141 gccgattatc cttatttaag caacttcgaa cgggccattg atgtggcgct tgaacagccg 343201 taccttgaaa tcaattcctt cttcagaaga aatggcagcc cggaaacaga agtgcaggcg 343261 atgaagacac tttcatattt cgatattatg aatctcgctg accgagtgaa ggtgcctgtc 343321 ctgatgtcaa tcggcctgat tgacaaggtc acgccgccgt ccaccgtgtt tgccgcctac 343381 aatcatttgg aaacaaagaa agagctgaag gtgtaccgct acttcggaca tgagtatatc 343441 cctgcttttc aaactgaaaa acttgctttc tttaagcagc atcttaaagg ctgataaatg 343501 tgaaaagccg ccgcatatca tcaggcggtt tttttctgca aactgccgga atgagaacag 343561 actggagacg aatagatatg aaacaaagaa tcattgatga attaaaacgg atcgagcagt 343621 catacggagt caaaatcgtg tatgccgtcg agtcaggaag ccgcgcatgg ggatttccct 343681 cgcaggatag tgattacgac gtccgcttta tttatgttcc gaaaaaggag tggtactttt 343741 caattgagca ggagcgtgat gtcattgagg aaccgattca cgatttgctg gatatcagcg 343801 gctgggagct gagaaaaacg cttcggcttt tcaaaaagtc aaaccctccg ctactcgaat 343861 ggctgtcctc agacattgtg tattatgaag catttacgac cgcagagcag ttaagaaaac 343921 tccgcacgga ggcatttaag cctgaagcaa gcgtgtatca ctatatcaat atggcgagaa 343981 ggaacgtcaa ggattatcta caaggacaag aggtcaaaat taaaaagtac ttctacgttc 344041 ttcggcctat tttggcctgc caatggattg aaaagcacgg aaccataccg ccaatggact 344101 ttactgtttt gatgaatgaa cttgttgctg aacccgagct gaaggctgaa atggaaacct 344161 tgcttgaacg gaaaagaaga ggggaagagc ttgacctcga agcaagaatc gatgttattc 344221 accaattcat tgaaacggaa atcgaaagaa tcatggaagc ggcaaaagaa ctgaaggcag 344281 agaaaaaaga tatgacatct gaattgaacc gtttgctttt gaatacggtt gaagaagtgt 344341 ggaaggatgg aggaagctga tgttttttgt cgcttccttt tctcctttat tcgacagaat 344401 ccccccccga ctttctaact atctgattgt ggcaaaccca caaaaataat cagaatcttt 344461 gtattttgag aatattgtga acgctggttt tgtccattta caataaactc atacaaatac 344521 ttcttagatt gcggggtgtt gaggttggaa gtgatcacaa gagatttttt cttattttta 344581 tccaaaagcg gctttctcaa taaaatggcg aggaactggg gaagtcgggt agcagcgggt 344641 aaaattatcg gcgggaatga ctttaacagt tcaatcccga ccattcgaca gcttaacagc 344701 caaggcttgt cagttactgt cgatcattta ggcgagtttg tgaacagcgc cgaggtcgca 344761 cgggagcgta cggaagagtg cattcaaacc attgcgacca tcgcggatca ggagctgaac 344821 tcacacgttt ctttaaaaat gacgtcttta ggtttggata tagatatgga tttggtgtat 344881 gaaaatatga caaaaatcct tcagacggcc gagaaacata aaatcatggt caccattgac 344941 atggaggacg aagtcagatg ccagaaaacg cttgatattt tcaaagattt cagaaagaaa 345001 tacgagcatg tgagcacagt gctgcaagcc tatctgtacc ggacggaaaa agacattgac 345061 gatttggatt ctttaaaccc gttccttcgc cttgtaaaag gagcttataa agaatcagaa 345121 aaagtagctt tcccggagaa aagcgatgtc gatgaaaatt acaaaaaaat catccgaaag 345181 cagctcttaa acggtcacta tacagcgatt gccacacatg acgacaaaat gatcgacttt 345241 acaaagcagc ttgccaagga acatggcatt gccaatgaca agtttgaatt tcagatgctg 345301 tacggcatgc ggtcgcaaac ccagctcagc ctcgtaaaag aaggttataa catgagagtc 345361 tacctgccat acggcgagga ttggtacggc tactttatga gacgccttgc agaacgtccg 345421 tcaaacattg catttgcttt caaaggaatg acaaagaagt aaaaaaggag agattatcat 345481 gacaacacct tacaaacacg agccattcac aaatttccaa gatcaaaaca acgtggaagc 345541 gtttaaaaaa gcgcttgcga cagtaagcga atatttagga aaagactatc cgcttgtcat 345601 taacggcgag agagtggaaa cggaagcgaa aatcgtttca atcaacccag ctgataaaga 345661 agaagtcgtc ggccgagtgt caaaagcgtc tcaagagcac gctgagcaag cgattcaagc 345721 ggctgcaaaa gcatttgaag agtggagata cacgtctcct gaagagagag cggctgtcct 345781 gttccgcgct gctgccaaag tccgcagaag aaaacatgaa ttctcagctt tgcttgtgaa 345841 agaagcagga aagccttgga acgaggcgga tgccgatacg gctgaagcga ttgacttcat 345901 ggagtattat gcacgccaaa tgatcgaact ggcaaaaggc aaaccggtca acagccgtga 345961 aggcgagaaa aaccaatatg tatacacgcc gactggagtg acagtcgtta tcccgccttg 346021 gaacttcttg tttgcgatca tggcaggcac aacagtggcg ccgatcgtta ctggaaacac 346081 agtggttctg aaacctgcga gtgctacacc tgttattgca gcaaaatttg ttgaggtgct 346141 tgaagagtcc ggattgccaa aaggcgtagt caactttgtt ccgggaagcg gagcggaagt 346201 aggcgactat cttgttgacc atccgaaaac aagccttatc acatttacgg gatcaagaga 346261 agttggtacg agaattttcg aacgcgcggc gaaggttcag ccgggccagc agcatttaaa 346321 gcgtgtcatc gctgaaatgg gcggtaaaga tacggttgtt gttgatgagg atgcggacat 346381 tgaattagcg gctcaatcga tctttacttc agcattcggc tttgcgggac aaaaatgctc 346441 tgcaggttca cgtgcagtag ttcatgaaaa agtgtatgat caagtattag agcgtgtcat 346501 tgaaattacg gaatcaaaag taacagctaa acctgacagt gcagatgttt atatgggacc 346561 tgtcattgac caaggttctt atgataaaat tatgagctat attgagatcg gaaaacagga 346621 agggcgttta gtaagcggcg gtactggtga tgattcgaaa ggatacttca tcaaaccgac 346681 gatcttcgct gaccttgatc cgaaagcaag actcatgcag gaagaaattt tcggacctgt 346741 cgttgcattt tgtaaagtgt cagactttga tgaagcttta gaagtggcaa acaatactga 346801 atatggtttg acaggcgcgg ttatcacaaa caaccgcaag cacatcgagc gtgcgaaaca 346861 ggaattccat gtcggaaacc tatacttcaa ccgcaactgt acaggtgcta tcgtcggcta 346921 ccatccgttt ggcggcttca aaatgtcggg aacggattca aaagcaggcg ggccggatta 346981 cttggctctg catatgcaag caaaaacaat cagtgaaatg ttctaagcgg gactaaatgg 347041 gcatcctccc tgcgggggtg tccatttcat ccatatacta taaaaaagag gaggaagtgc 347101 catagaaaac acacagctga ttatttcgat ttgtatttat atggcgggaa tgctgctaat 347161 cggctacttt gcttacaagc gtacgtcgaa tctgacggat tatatgctgg gaggacgctc 347221 tttgggtccg gcagtaaccg ctctcagtgc cggcgctgcc gatatgagcg gctggctgct 347281 aatggggctt ccgggcgcca tgttttctac tggtctgagc ggcgcttgga tcgtcatcgg 347341 actttgcctt ggagcgtggg cgaactggct ttacgtcgca ccacggctga gaacctatac 347401 tgaaaaagcg gggaattcta ttacaattcc cggattcctg gaaaatcgct tcggagatca 347461 aacaaagctt ctcagactgt tttcgggaat tgtcatttta gtctttttca cgttttatgt 347521 atcgtccgga atggtgtccg gcggcgtctt attcaacagc atcttgggga tggattatca 347581 caccggcctg tggattgtga cgggtgttgt tgtggcatat accctgtttg gcggcttttt 347641 ggcagtcagc tggacagatt ttgttcaggg gattattatg tttgccgcac tcattcttgt 347701 gccgatcgtt acgtttttcc acacgggagg agcaggtgat acagttgctg aaatccgctc 347761 tgtagatcct gatatgttta atattttcaa aggaacgagc gtccttggca ttatttcttt 347821 gtttgcctgg gggctgggat actttggcca gccgcatatt attgtgcgtt ttatggcgat 347881 aacgtctgtc aaagagatca aaagagcgcg cagaattggg atgggctgga tgattttgtc 347941 tgcagtaggc gcagtgctga ccggtttggg cggaatcgct tattaccatc agcgcggcat 348001 gacactgaag gacccagaga cgatttttat tcaattaggg aatatcttgt tccatccgat 348061 tatcacgggt tttctgattt cagcgatttt ggccgcgatt atgagtacaa tttcttccca 348121 gctgcttgtg acatcaagct ctctggtaga agatttgtat aagtcgatgt tcagacgctc 348181 agcttcagat aaagaactgg tgtttttagg ccgactggct gttctggctg tttcaattgt 348241 cgcgttggtt ctggcttggg agaaaaataa caccatcctt ggattggtca gctacgcgtg 348301 ggcgggcttc ggtgcatcat tcgggccagt tgtactgctc agtctgtttt ggaaacgaat 348361 gaccaaatgg ggggcactcg ccggcatgat tgtgggagca gcgactgtaa tcatttgggc 348421 gaatgccggt ctttcggact ttctgtatga aatgatacct ggttttgctg cgagtctatt 348481 atctgtcttt tttgtcagca tattgacgca ggctccgtca caagctgtca cagaccagtt 348541 caacgactac caagatacaa tgtcgcaata aagatcgaaa ggaggaggaa ggggctgtcc 348601 ctttttcctc ttttctcctt ttaagcggcc atttttttct tttggaaaca aacgtatttt 348661 tttctataca aaaagacccc gtatggatat gattaaagta aaaaaagtat aggagaaaaa 348721 ggtatggaag agcttttaga gagagttttt tcattttcag atgttgataa gctaattgat 348781 tttattagct atgaactgca aaagccagtg atactggaaa gcgcggattt ctttttgtta 348841 gcctataatt cttactatat taaccatttt gattctgcca accagcagac tattttttcg 348901 aaaaagtgtc cggtccagat ttttgagagg tttctgaagg acggaattat tgaaaaattg 348961 aaaacagagc ctgagccttt tcgcgtcaat aaaattgaaa gcattgggtt aaaccagagg 349021 gtggtcgtga gtgcaaagca caaaggggaa gtcatgggct acatctggat tcaggagctg 349081 gaccaaaatc tgacggatga agagctcgac tttttgtacg agacctcctt ccatgtcggg 349141 aaaatcattt ataaaacgaa taaattgaaa caggaaaagg aagaaaaagc agaggatctc 349201 atcaaacggg cgatctatca gcaatttacc tctgagaagg aactcagacg ggaagctgaa 349261 aggatcaaca ccgtgctgcc ttccatgttt tcagttgtta tcctgcacgc cgcaaatggg 349321 gatggggaag cggttgagga tttaaaggaa aatatcaggt cgtacctgaa tttacgggat 349381 aaggtcagtc atgtcttaac gatcgaatca aacattgtca tcgtcgtagc gagtttttcc 349441 caaaaaagct ccgtctcctc agcagcttct gagtttatta acaagctgtt aacacatttt 349501 cactttcaaa aaatacctac ccctatttat atcggtatcg gaaacgaata taatcaccta 349561 ttaaaacttg gcaagagcta cacagaagca cttgaagtca tcaaagccgc agaaatcacc 349621 ggcaatcagg aaaacattcc atatgaatat gccaaactcg gcatttaccg ctatttagaa 349681 agcatcgaac agaaaaatga atttttagaa tacgagaata aagatttagc tttattaaaa 349741 gcaaaagacg aagaaagcag cactgagctg ctcaaaacct tggaaatcta tctcctcaac 349801 aactgcaaaa caaaaccagc ggcagaacag ctgtttattc accaaaatac attgaattac 349861 cgcatcaaac agattactga gatgacgtcg atcgatttaa gcgatttcag aacgcggtgc 349921 cagctctatc tcgatttgat gctgatgaaa aagaaataaa aaagaaacca gtacttgtac 349981 tggtttcgtc ttcacttaaa atcctctgta aacatacgga tcatcaggtt ttttaatggt 350041 attccagtca gttactttga cgacagggag agttgacttg aatggctggt aatattctga 350101 ggccagagtg cccttaatgt gaatccattc atcatccttg atgtccatgt ccttcggaaa 350161 ttccacaagc atcccgtaca cgccggaatc agcgatacag tgaatgatgc caaaccttaa 350221 tacgaacagc tgatttttgt taattgcgtt tcctttgtaa gcaaatccat gaaattctat 350281 cgtccgtccg agaaattcac ccggatagtt atagatggtt tccattcctt ttaggaaatc 350341 gtcatcggtc agagaaatct cttttttgct ggaatactta ttaaacagct gtttcatttg 350401 tttgtcatag ctgtcttgcg cgtaataaag gctggcatca ggccgcaaat actgtgtttg 350461 ggagtagtga tctccgctct ccatcgcctt aaacgagaac ccttttgttt tgactatgga 350521 tgagtcaagc gttgcaatcg ggaagaagat gcctgacacc aaaggaaaaa gaaaaacaac 350581 ataaatcaaa taacgctgat aaaatggctt gttttgttca tggtcatgct cgtgatcatg 350641 gccgcacccg caatcatggt catggtgatg tccgcttttt tcaggcgact tgataaatag 350701 atatgcttgg acggcggtca gaatggccag caggaagatc gcaataaagg aaagataggc 350761 atatttcata ttgatatatt ttgttagatt tcctgaggca tgcagatgat aaaagaaaaa 350821 cgtaaatccc atcagcacca ataaacgaaa catccaatca cccctttacc agtagtgatc 350881 ccgctaaaac aatcacgaca atgtatgtaa tcagcaggaa aacaaatcgt tttttgaagg 350941 ccgcaagcat catcaataga ttcttaatat ccaccattgc accaaagacg agaaaggcga 351001 ttaacgatcc taatgaaaac gtgctgctga aggaagacgc gatgaacgca tcaacttctg 351061 aacaaagcga caggacaaac gccagaccca tcatcacgag ggaagaggat acatcattct 351121 gcccgatcgc aagcagagtg gatgttttga catacgtctg catagcggct gcgataaagg 351181 cgccgatgat taaatatttc cccacggaga aaaattcatc aatggcatgc cgcaaggtcc 351241 cgcccagttt ttggagcaag gtgccgtgat gatgatggtg gtgcccgggt tcatcaggct 351301 ttaaaagctg gttatcctta aattgatagg ataagatgac cccgatgatc agcgaaacgg 351361 cgagagccag tccgcctctg taaaagacca cgctccatct attcccgaac gcaatataag 351421 tagaaaataa aacgatagga ttaatgatag gcgcggtcag catgaaagca acgcccgcat 351481 gcagaggaac tccctttaac agaagccgcc tcgtaatcgg gatgatgccg cattcgcagg 351541 cgggaaataa aacgccggcc agcgcaccga ataaaacggc gagaaaacgg tttttcggca 351601 tgattcttgc aatcatttct tcagaaacaa acatttgaat gattccggaa agtatgacgc 351661 caatcagaat aaacggaatg gcttctatta aaatgctgat aaaaatagaa ttcagctgaa 351721 gaaaagatga ttgtgctgtc acaataaaac ctccgctcat gttaagctgc ctttcttatg 351781 ataccagaaa aaaaggcact gcttgtttga cggaggaggg gaaaggatcg tttcactttg 351841 gttaggattc caaaaagccg agtaggatac tgcctgtttc tgcagcttct tttccgagcc 351901 aaatcaggtg tccccatgag tgaagcaaac agagaacagc gccacgaatg tgctcttttg 351961 catgatgtgc atgtgacaag tcaaccaatc cgtcataaac actttgcata atcagcacgg 352021 gacatatgat ggcttgcagg tcttttaaag agacagcggc ggtttgtgac aagtcaatca 352081 gaaatccttc acccgagcgc tgccggctgt tcattttccg aaatgcttct atgtcttttt 352141 cattcatcaa ggacttgatt cgctgaaacg gaagcgtgct gaattggggg ctcatagctc 352201 gaaacatcaa acgcgggaaa gcgttattca aggaagaaat cagcttccat atccactttt 352261 ccaccggcgg gcggaagaga atttccccca atttatattc agtgtctttt ggggtgagcc 352321 actctttggt gactgcggat tgcagggtca atgtatttac tctttccgga taatgtgagg 352381 caaagcatat gccgctcggc cctcctgctg agatggcgat cacatggaca ctctcgattt 352441 gtagatgatc taataatttc acatagaaac ggcaggcatt ggcaagactt tttccaattt 352501 cttttgacgt ccgtccatag ccaggccttg aaggcgtaat gatggaatac ccttgttcaa 352561 tcaacgctgt gtatccgaat tcctcgtaac aatttgaatg cccgccatgc atgacaagga 352621 tcggagttcc cttgcctgtc acagaatatt ctagtgtacc gccatcgaag gtgatcgttt 352681 caactcgtct tttcatctgt ttcacccaat tggtttttgc ctattataga gttttcagca 352741 attgaccaca aggtagaaga aatgaataaa caaaggccct tgaaatatga tatactttgt 352801 attgatattc attctcaatt aaaactttga tatagatgtg aacgggaggc aggacggatg 352861 gctgagaatc aagaggtata tgacgttacg attataggcg gggggccgat cgggctgttt 352921 actgcttttt actgcgggat gcgggagctg aaaacaaagg taatcgaatt tttgccgaag 352981 ctcggaggga aggtgtcttt attctttcct gagaaaatca ttcgcgatat cggcggcata 353041 ccggggattg cgggaaagca gctgatcgag cagctgaagg agcaggcggc aacgtttgat 353101 cctgatatcg tattgaatca gcgtgtgacc gggtttgaac gcctagatga cggcaccatt 353161 gttctgacgg gttctgaagg gaaaaagcac tatacaagaa ctgtgatttt ggcttgcggc 353221 atgggtacac ttgaggtcaa tgagtttgac agcgaggatg cggcccgata tgcgggcaaa 353281 aatcttcatt atggagtgga gaagctcgat gcgtttaaag ggaaacgcgt ggtgatatca 353341 ggcggcggag atactgcggt cgattgggct aatgagcttg aaccgattgc ggcgtctgtg 353401 actgtcgttc atcggcgtga ggaattcggc ggaatggaaa gcagcgtgac gaaaatgaag 353461 caatcatcgg tgcgggtgct tacgccttat cggctggagc agttgaacgg agatgaagag 353521 ggcatcaaaa gcgtgaccgt ttgtcatact gagtctggcc agaggaaaga catagaaatt 353581 gatgagctga tcattaatca tgggttcaaa attgatctcg ggccgatgat ggagtggggg 353641 ctggagattg aagaaggaag ggtgaaagct gacagacata tgcgaacgaa tcttccgggc 353701 gtgtttgtgg cgggcgacgc ggctttttat gaaagcaagc tgagattgat tgccggcgga 353761 tttacggaag gcccgacagc ggtcaacagt gccaaggctt atctggaccc taaggccgag 353821 aatatggcga tgtattccac ccatcataaa aaattggtgc ataaataaaa cagcccttga 353881 ggaaaagggc tgcttgccat caggtgtgaa ggagtttttt ctctgcatgt tgattgtgga 353941 tgaaagctag caattcatcc tgttcttgta cggctgtgaa tccataaatg ccggcagctg 354001 agtcatcgcc tatgcagacg ataggagggc ggcttgctga cggttccggc aaaatgccaa 354061 tttgttcgcc accattgatc aattgctgaa cggacagctt gtttgggcaa atgaccatgt 354121 gcagcgggga ttcactgatg gtacgctgaa tcatgtgggt gaaccggtca tctatgacgt 354181 tttcatgagt gatataaaac gaacaggatt catgcttttg catgttttcc actgcatggc 354241 ggctcccgac aacaagacgt ttctctgaat caggctgaat ggcggtgaca agaaagcccc 354301 gtttctcaag ctctgtcttt gcttgctcag atgctgcact cagtttggct gtcagctggc 354361 ggatgtcgat tttctgagaa gccagtgctc tgaaaaattc acaaaccgcc cggcgcgatg 354421 tgaaaaaaac gtcttcaaag gtgccaatct ttcgaagaat ttcttcattg acaggcatgt 354481 tttcggtccg ccatttcggc cactcgatga gatcggcgcc ggaatcgcgc agcttgtctg 354541 caagcgggtc ttcatcttcg ccatgagtca caaccatcaa atgccgtccg atgagcggtt 354601 tgctttcaaa ccagctgtgt gtttgaaagt tgacgatgtc tccgatgacg ataatcgcag 354661 ggtttgtaat ctggtgttcc tgcacttttt gctgaatgtt ctcaagtgtt cctttcacac 354721 tccgctggcg gccccacgtt ccccattgga tgacaatgac agggacagaa ggcgatttcc 354781 cgtatgaaat aagctgctgg caaatataag acaagttctt gacacccatg taaaaaacaa 354841 gggtttgaac gcttcgggcc agcccttccc agtcaaggtt cggcgtgcct tttaatgatt 354901 tatcatgcgc tgtaatcatg gcaaaagacg atgcaaaatc ccgatgcgtg acggggatgc 354961 ccgcatatag cggcgctgca attccagagg tgattcccgg caccatttca tagcgaatgc 355021 cgtgctcatg aagagcatct gcttcctcgc cgactctgcc gaatacgctc ggatctccgc 355081 ccttcaagcg aacgacggtt aacccattta atgctttttc aaccagcagg gcgttaattt 355141 ctttttgttt cataaaatgg cggtttggca gttttccgca ataaataaac tggcagtccg 355201 gtgatgcaaa ttcgagcagc ttcgggttgg cgagccggtc atataaaatc acatctgctt 355261 ccttgagcgc ctgttttcct ttgatggtga gcaggcctgg gtcgccgggt ccggctccca 355321 cgaaatatac gattccgttc ttcatgatca tgtcatcctt ccgtcactgt aaaaaatgaa 355381 ggaccactag aaaagtgatc cggtcttttg atcaatatac gagataaaca tgttctcctt 355441 cgatcagcgt ttcatatgtt ttgacgcatc cgtggtcagg ttcttggacg attccgtctt 355501 ctaaggaaat tttccagtcg tgcatcgggc agaaaacata ttgaccgctg acgatgcctt 355561 ctgccaggac gccgccctta tgcggacagc ggttttcaat ggcgcggatg cttccgtctg 355621 aaagcttgaa aaccgcgagc tccttatctt caatatacac tgttttgcct aattgttcag 355681 gcaattcttc aatttttccg atacatactt ttgttacgtc tttgtttacc atgtccattc 355741 ctcctcaatg atagtttttg tcattatgat gtggtcacga cattttcaaa taattcttta 355801 gaggtttgtt tatcctctaa aaagtctttc cacggatcct tgtggacaga gagtgtttca 355861 ttcattcggc cgttcagctc ctgccgcttt tccggatcgt ttaacacgga ttggacatgg 355921 gataaaccga cgcgctcaag ccatgcggac gtacgctcca gatagtttgc ggtttccctg 355981 taatattgca ggtaagcgcc cgcgtattct aagacttctt catttgtttt caccttcatc 356041 agcaaatcgc cggcacgcaa atgggttccg ccgtttccgc cgacataaag ctcccagcct 356101 ccgtcgatgc cgacaacgcc aaggtcctta atgccggatt ccgcacagtt tcgcgggcag 356161 gcagacacgg ccattttgac tttgtgaggc gtgttcagcc cttcgaattt tttctcaagc 356221 gcaatgccca gtgccatgga gtcttgtgtg ccgaagcggc agaattgctc gcctacacat 356281 gttttcactg tgcggagcgt ttttccgtac gcgtagcccg atggcatatc aagatcttcc 356341 cataccttcg gaaggtcttc ttttttcacg ccgataagat caattcgctg gccgcctgtc 356401 attttcacga gcgggatctc atatttgtca acgacatcgg cgatcttgcg caaatctgtg 356461 gagttggtca cgccgccgta catccgagga acgactgagt atgttccgtc tttttgaata 356521 ttggcgtgca ttcgttcatt aacaaagcgg gatgtccggt catcctcgta tttggttgga 356581 ttgatcatgc ctaagtagta gttcagagcg ggtcggcatt tagaacagcc ttctggcgtt 356641 ttccagccga gcacattcat gacttctctt gtatgtgaca gccctttggc tttgatttct 356701 tctacgactt catctctcga caatgtggtg cagccgcaaa tggcttcttt ttgcgctgac 356761 gcatcaaagt ctgatccgag cgtatgctgg aggatttctt ctacgagcgg cttacagcct 356821 ccgcatgagc gggatgcgcc ggtgcatgct ttgatttcgt ccgttgacga gcagcccttt 356881 tcctgtatgg cttgaataat cgcacctttt gacacgccgt tacagccgca gatgatttca 356941 tcgtcgctca tcgctgcggt tatgcttgtg cctgcttcct ggctgagggg ctgtaagatt 357001 gatattttag aggtttcaga gatatcggct tctttttgaa tcatagaaaa caggcgattg 357061 ccttcgctgc tgtcgccgaa taaaacagca ccgacaattt gattgcctct caggacaatt 357121 tttttataga tgccgtcctg ctcatcgaag actttaatcg cttttttctc ctctgattcg 357181 ttaaagtcac cggcagagaa gacctcgacg cctgatacct ttaactgtgt ggagagaacg 357241 gagccctcat acggttttgt ttcgatgccg cacatatgct ttgccagcac ttttgcctgt 357301 tcatacagcg gcgccacaag cccgtaggcg attcctcggt gctcggcaca ttcgccgacc 357361 gcgtaaatgt gcgggatttc agtctgcata taatcgttga cgatgatgcc gcggttaacc 357421 ggaatgccgc tctcggcccc gagcgttgta tttgggcgga tgccgacagc catgacgact 357481 aaatcagctt caatgcttgt gccatccttg aatcggaggc cttcgacacg gtcgtcaccg 357541 acaatttctt ctgtttgctt ttcaagtaaa aaggtcatac cttgtttttc taactcgttt 357601 tgcagcaggc gtcctgccgt tgcatcaagc tggcgctcca tcaggaatgg ggcaaggtgg 357661 atgacggaca cgtccatgcc gagattcagc agtccgcgag ctgcttccaa accaagtagt 357721 cctccgccga tgacggcagc ttttttatat tgttttgacg cggcgagcat tgtgtctgta 357781 tcttttatgt cccggaaagc tgtgacgcct tttttgtctg cgcccggaat cggaaggata 357841 aaagggaccg atcctgtcgc caggatcaat tcatcgtaag gctggattct gtctgcatct 357901 gtgatgactg ttttgttttc cgtgtccact ttgatgactg tttcatttgt atacaattga 357961 atgttgtttt cttcgtacca gtcccaatcg tttaacgtaa tatctttaat atctgtatcg 358021 ccttgaagca cttttgacaa aaggattcgg ttgtaattgg gatgcggttc ggcaccgaaa 358081 attgtgatct gaaactcgtc tttagcaaca ctcagtatct cttcaatggc ccttaccccg 358141 gccattccat taccaacaag aactagctgt ttttttccca tcagatgatc cgctccttat 358201 caaatgtttt ttccagcgta gcacagcaaa aaggaatatt taagatacat gttataaaat 358261 gtaacaaaat atacgaaaag ttctaaaaat tttatgaaaa atttaaatag gtatgattcg 358321 gacggcgcat accttaaaac cgggcatttt acaggctgga tctaaggctt ccccgattaa 358381 atcattcaca ttttgagcgt ctgcccaatg gatgggaaca aaaacggtat cttttctgat 358441 ttgttctgat aatttgctgc ggacggtgat gcttccccgc ggcgattcta tttttaccag 358501 tacacggtcc tcgatattgt aggtcgctgc tgtttgcgga tggatctcca taaacgattc 358561 aaaatgtctc gcggcaaggg cggcgctttt tcttgtttgg acgcctgtta agtagtgaga 358621 catgactctg cctgtcgtta aataaagcgg ataatcggct gtcggcttct cttttggaac 358681 aggtggttcg tttggaatca cacttaatgc cgctttttga tccggatgag caaatgattc 358741 tgtaaacaag cgcccagttc cgggatgatc agattccgga cacggccaat gaatgccgcc 358801 ttcacgtctg agcctgccgt atgagatgcc tgaataatcg gcaatcccgc ctcggctcgc 358861 ttctctcaat tcattgaaaa tatcctccgc tgacgtataa gaaaagtagc ggcccttgcc 358921 gagagcggat gcgagatcac aaatgatctg ccaatcatgc tttgcttcgc cggggcatgg 358981 ccggcttgct tctcttaatg tcacgcgtcc ttctacattt gtcatggtgc cttcatcttc 359041 taagtaagag gaggcaggta aaatcacatc tgcgtatttc gcagtctcag aaataaacaa 359101 atcgattgcg acaaagaatg tcagtcttct taaagccttt ttcacgagat ttgcatttgg 359161 actggaaaca gcagggttgg agcacatgag gaacagtcct ttgatgtcgc cgtcattgat 359221 tttttccatc atttcatagg ctgagacacc ttttcgcggg agttcatcct gatggattcc 359281 ccacactttc gcaatatgcg cccggtgttc ttcgttttcg atagaacggt agcctggaag 359341 ctgatcggct ttttggccat gctctctggc gccttgcccg ttgccttgtc cggtgatcgc 359401 cccgtagccc gagtaaggtt tgccgatttt tcctgtgatc agcaccatgt ttaagaagcc 359461 tttcacagcc gctgttccat cggtttgctg ttcaatcccg cgggctgtaa acagcatgcc 359521 ggacgtttcc ttggcaaact tcacagcagc ttttcttata tccaccagcg agacactcgt 359581 ctgttcggcg atgtcattca ggtccaacga gtcagtatgc tgcttcagct cttcgaatcc 359641 atttgttcgt gattgaatga aatcctcgtt tataagctgt tcgtcaatga tgattttgac 359701 gagaccgttg gcaagggcgg cgtctgtgcc gggtttgatt ttcagatgaa gatcggcgat 359761 tttcgttgtc gctgtttcac gaggatcaat ggcaatgaag taagctccgt tttctttcgc 359821 tttttcaaaa tacggcataa tcgtaggctg gcattccgca atattggtgc cggccagaat 359881 gatcacacgg gtgtggggga tgtctgataa aggattcgtt aagcctctgt ccgcgccgaa 359941 tgtttggttg gctgcggtgg ctgctgcgga catacaaagt ctcccgttgt agtcgatgta 360001 ttttgtctgt aagcctactc gtgcgaactt ccctaacaaa tacgcctctt catttgtaat 360061 cgaggcgctt ccgtataccg ccatggcgtc atgtccgtgt tcagtttgga tcattgtcac 360121 ttggtctttg atatgattca gtgcttcttc ccaggaaaca ggcataaact cgccgttttt 360181 cttcagcagc ggccgggtga tgcgggagga gttcaaggca tgctggtgag cattcatgcc 360241 cttgatgcat agccgaccct gtgtcgtagg attatcaatc ccgatcgcag tgtacttttt 360301 gcgcgtgacg atggtttgtt ccacgagctg cattttgcac tgcatgctgc aaaacgggca 360361 ttgagtgtca tatgtttttt ctgattggac gtcttgctgt ttatcacgga aatatctaag 360421 cagtcgttca gtcaaaatgc ctcatccttt cttatatgcg cccgtctcta cagtcgggtt 360481 ttgaatcagt gacagatctg tttggaggct ttccagcagc tgtgccctta ggtcttcttc 360541 gaatagcact tctctgatat gaacgatccc gagacggtct atccactgat gaacaccttc 360601 taagtaatga gccgtttccc gataatactg gatcagtcct ttgatcatgc cggcagtgct 360661 gtcttcgttc tcagtcacgc aaaacaaagc tcctgaacgg gcatgagttc cccggacgcc 360721 gccgatgtga atgtcccagc cagcttgtgt ccgaattgcg ccgacatctt gcagggcggc 360781 ctcggtgcag tctgtttcac atgataagct gatagaaatg ggagcgggta agggaagcat 360841 ctcaagttgt ctttcgattt gggctgccag ctgctgaatc gatcgatttt gcccgcatgt 360901 acatgctttg atgctttgca gcgcgtgtcg gtgttcatta gtgtaaacgg gcattttcag 360961 gtcttttttc atgttcggga gatccgcagg cttgatcccg gaaagcttca gcctttggcc 361021 gtgagtgatg gatacgtcgg gaatgctgta tgcctcaatg atgttggcga tggttcttag 361081 ctgctccgcg tttgtccgcc cgccgtacat ttgcggaatc aggatgcatg tctcttcagt 361141 ggctggctca ggctggacaa acccagggta cagcatttcc agatagtatt gaatcgcagg 361201 aacacaagta ctgcatccgt tttttgtttt ccagtcaagc tggttcatca cttctgccgg 361261 attagtgaat ggcctgcgct gaagctcagc gatgatgtcg tcttctgtaa aatcagtaca 361321 gctgcaaaac gaaggtgtgc tggcgggctt cgtatattcg ctgttggtca tgtatctcaa 361381 aaggtcttca acgagcggtt tgcatcctcc gcaggaccca gtggctttgg tgcagtgctt 361441 gacttcctca acagttgtta agctattcgt gtgcaccgcg tcttcaatcg cgcctttcgt 361501 cactgtgttg cattggcaaa tcgtttcact ggaaggcatg gattcaaata aagggccgct 361561 tgtctccggt tcgatgatct gttttttggc aatggagatg tctcgttgtt taagcaggct 361621 gtcgagaagc cgctgcttgt cacgggtgtc tccgaataaa ataacgccgg ccagtttgtc 361681 atctacaaaa agcgcttttt tataaacgcc tgcttgttcg tcgtagattt tgatgctcgt 361741 cgtgcgttca tcctcttgga tctttcctgc tgaccacaca tcgattccag ctatttttaa 361801 cgccgcagat ggtgctgagc cttgatattc ctcacatgga acgccgcaaa tatgactggc 361861 gagcgctttt ccctgctcat aaagcggagc caccaatccg tacaccgttc cgttatgctc 361921 agcgcattca ccaacggcgt agatattcgg ttcgcttgtc tgcatgaagt cattcacgat 361981 gatcccgcgg ttcactttga ttccagcgga tacagccaat tcaatattcg gtttgacgcc 362041 ggccgccatc acaatcaagt ctgcttttaa tgaagagcca tctttaaaat ggattcggtc 362101 tgccttcgtg gcgccggaaa tggagacggt gtctttctcc aaaagaaagg ttaggccttt 362161 ttgttccagc tctgtttgca gcagccgcgc cgctgtttga tcgagctgtt tttgcataat 362221 gccggcggag tggtgaatga cgctgacatc cataccgaga tgctgtaaac ctactgcagc 362281 ttccagtcct aataagccgg ctccgattac cgcagccttt tgaaagtgct gggccatgtt 362341 catcagcgct tggcagtctt ctattgtccg aaatccatag acaccttttt tgtctgcccc 362401 ggggataggg agaatatgag gggaggagcc tgttgccact attaatttgt catacgacag 362461 agtgcgtttc cgatctgtga tgacctgctg ctgatctgta tcaatctgaa taaccgtttc 362521 gcctgtgtaa agcgtgatcc cgtgcttgtc gtaccaatcc ttgctgttca gtgtaatatc 362581 atcgagtgac gcttcaccct gcaatacaga ggataagaga atgcgattgt aattgggatg 362641 cggctcgctt ccgaaaatga caatctcaaa catgtggcga ttcagcttta atacttcttc 362701 aatacagcgg attccggcca tgccgtttcc cgctaacact aatctttgtt tcttcatgta 362761 tcagacctcc tttggcgaag ctcgtaagtt ttctcctatt aaaaattatg tcacaatgca 362821 ttgttaacgc attaaacgtg tcacaaaaac ttacacatgt cttttccaga aaataatggt 362881 cctatatcct tgattcagaa aatgtaaaat aatgagggtc tagaaagggg aatcttatga 362941 agctgtcgga actgaaaact agcggtcatc cactcacttt gctctgttcc tttttatact 363001 ttgatgtcag ttttatgata tgggttatgc ttggggcgct gggtgtttat atttctcagg 363061 attttggcct gtctcctttt gagaaagggc ttgtcgtagc tgtgccgatt ttatctggat 363121 ctgtgtttcg tatcattctt ggtattttaa cggacagaat cggaccgaaa aaaacggcag 363181 tgatcgggat gctggtgacg atgattccgc tgctttgggg gacattcggc ggccgttccc 363241 tgactgagct gtatgccatc gggattctgc ttggcgtggc gggagcaagc tttgctgtag 363301 cgctgcctat ggccagccgc tggtatccgc ctcatttgca gggacttgcg atggggattg 363361 ccggagcggg gaacagcggc acgttgtttg caaccctgtt tggccctcgt ctggcagagc 363421 agttcggctg gcacattgtc atgggaattg cgctaattcc attattgatc gtctttattc 363481 tttttgtatc catggcaaag gattcccctg cacagccgtc tccccagccg ctcaaaagct 363541 atctgcatgt gtttgggcaa aaggaaacat ggtttttctg cctgctgtac agcgtcacat 363601 ttggcggatt tgtcgggctc tcaagctttt tatctatttt ctttgttgat caataccagc 363661 tgtcaaaaat tcacgcaggg gacttcgtta cattatgtgt ggcggcgggg agctttttcc 363721 ggcctgtcgg gggcttgatt tcagatcgtg tcggcggcac gaaagttctt tctgtattgt 363781 ttgtcatcgt ggcactgtgt atggccggag tcagtagcct gccatctctc tcaatggtta 363841 ttgttctatt gtttgtcgga atgatggggc tcggaatggg aaacggcgca gtattccagc 363901 tcgtgccgca gcgcttccgc aaagaaatcg gcatggtgac gggaatcgtc ggtgcggccg 363961 gaggaatcgg agggtttttc ttgccgaaca tcttaggatc tctcaaacag atgacaggca 364021 catatgctat cggttttatc acgttttcct gtatcgcgct gctggcgttt gcacttgtgc 364081 ttgccgcagg ctattactgg cggaaaagct ggagcgcgga aagcagcccg gcggatgttt 364141 aggattttga cggacacgcg tttgtgcgtg tcttttttat tttctcttga ttttcaacag 364201 tgaaccgatc aaaataaata gtaattatta cgatttgtta gtgagaggag ttttctgaat 364261 gaatcaacat acgctgctcc cgaaaaaaac ggagcgtctt caatactttg gatcggtcag 364321 tccgatcaaa ggcgagaaac cagtggaaaa agagaaaatg aaggacctgc aaaatatcag 364381 gaaggattat ttttttgaca ttcagcatgt aggtgtagct aatgtgtccc atccagtcac 364441 aatcacttct gccatgatgc ctgccgagca aacaacggct gcgaacttta caatgacttg 364501 taatttgccg agaaatcaga aggggattaa catgagccgg ttaacagagc tgctgcaagt 364561 ctatcatcaa aatggctgga ttctctcatt ttcctctctt cagcaattta cgaaagagct 364621 tgcagaaaac atggacacat catctgccac agttgaagtg aggtttccgt ggtttttcga 364681 acggaaaagc ccgaagcttg agaaagcggg tttgatgcat gctgatatat tcatgtctgt 364741 cacctatcgc aaagatcagc cgtttaaaca gcgtgccggc atctcagcaa aagtaacgac 364801 tctgtgccct tgctccaagg aaatcagcga atacagtgcc cataatcaga ggggaacggt 364861 cagcatttgg gcggatattc acccggccgc atcgctgcca agtgatgtta aagctgattt 364921 gcttcacgcc gcagaatcaa atgcttctgc gagactgcat ccggtattga agcggcctga 364981 tgaaaaagcc gtgacagaaa cggcctatga aaacccgaga tttgttgagg atctcgcccg 365041 gctgattgct gcagatttgt ttgagcttga atgggtgtca gcctttgaga ttgaatgccg 365101 aaatgaagaa tcgatccatc ttcacgatgc ctatgcgaag ctgtgttttt cgaaggaagt 365161 ggataaaata tgaaactctc attattcatt attgcagttc ttatgccagt catcctgctg 365221 tcagcctgct ccgatcatgc agaagaacac gcaagtatca atacaaagaa aacggtcgaa 365281 aacataacgg acgttcgaaa aacagcaaaa acaagcattg attggacaaa gccttcgggc 365341 ggagaatacc cggatattaa acagaagcat gtctggattg atgtgaatgt gaaggagcag 365401 aaggcttaca tcaaggaagg aagcaacacc atctatacaa tgatgatttc ttctggtctt 365461 gatcaaacaa aagatgatgc tacgccaaag ggcacctttt atgtagagcc tgaacgggga 365521 gaatggtttt tctccgaagg ataccaggaa ggcgcagaat actgggtatc atggaaaaat 365581 cacggtgaat ttttatttca tagtgtgcca atgactaagg atcaaaaagt catcaaaacg 365641 gaagcagaaa aactaggaac gaaagcatct cacggatgta tcaggctgac cattccagat 365701 gcgaaatggg tatatgaaaa tatccctgaa catacaaaag tggtgatcag ctgaattgaa 365761 aaccgttgac aaaaaggaaa aaagaccata caatttaaat cgtaacaatt acgttttatg 365821 ataaatggct tatcattgtc tgtgcatctg tgaaaagcgg aaaggcatcg attaaggatc 365881 ttgctgtcgg caaaggcaag gatttgcgat ggggaaaagg attaaacgcg gttggagtct 365941 ttactgattt agaaatcggg cggcagcgag aaatgagcgc gaaaagctgc tctacaccat 366001 tgtacatacg gcgaagtatt caatttaaat cgtaatcatt ctattttaat ggaggcacta 366061 ttatgaaaaa aattccggtt accgtactga gcggttatct cggtgcggga aaaacaacat 366121 tgctgaacag cattttgcaa aatcgcgaag gcttgaaaat agcggttatc gtaaacgata 366181 tgagcgaggt gaacattgac gcgggcttgg ttaagcagga aggtggcctt tccagaacag 366241 atgaaaagct tgtggaaatg tcaaatggct gcatttgctg cacgcttcgc gaagacttat 366301 taattgaagt tgagaagctg gcaaaagacg gacggtttga ttatatcgtc atcgaatcga 366361 caggaatcag cgaaccgatc ccggtggccc agactttctc ttatatcgat gaagagatgg 366421 gaatcgatct tacaaaattc tgtcagctgg atacgatggt gacggttgtt gatgccaacc 366481 gtttttggca tgattatcag tcaggcgaaa gccttctgga ccgcaaagaa gcattggggg 366541 aaaaggatga aagagaaatc gccgacctct tgatcgatca aattgagttt tgcgatgtac 366601 tgatcttaaa taaatgtgat ttggtcagcg agcaagagct cgaacagctt gaaaacgttc 366661 ttcgtaaact gcagccaaga gccaggttca ttcgttccgt caaaggaaat gtaaaaccgc 366721 aggagatttt gcatacaggg ttatttaact tcgaggaagc gagcggatcg gccggctgga 366781 ttcaagagct gacggcaggc catgcggaac acaccccgga aacagaagaa tacggtatct 366841 cttcatttgt atataagaga cgtttgccgt ttcattctac acgattttac cgttggttgg 366901 atcaaatgcc aaagaacgtg gtacgtgcca aaggaatcgt ctggtgcgca tctcataaca 366961 acctcgcttt gctgatgtcg caagcaggtc cgtcggttac gattgagcct gtatcttatt 367021 gggtggcggc gttgccgaag cttgagcagg agcaagtcaa acagcaggag ccggaaatcc 367081 tggaggagtg ggacccggag ttcggcgacc gcctaacgca gctagttttt atcggaactg 367141 acctggatga agaaacgatc acgaaagagc ttgatcaatg cctgttgact gagtatgaat 367201 ttgattccga ctggtcgctg tttgaggacc cgtttaaatg gaagctgaat caatagaaaa 367261 aaagccgtcc catggggaac ggcttttttt aatgaaacgt ttgtttaaac ataatgagcg 367321 tattttttct caaggatatt ctgaaagacc gcggcaatgg agcagatggc ccaataaatg 367381 agagcggtca gaatatacat ggtcatataa tcaaactctc tgcccccgat gattttcgca 367441 tgctggagca attccggcac tgtaatcatc gcagcgagag aggacgcctt gatcaagtcg 367501 agcaatacat tggcaagcgg aggcagcgca atacgtatcg attgcggcaa aatgatgccc 367561 ctcatcgtct gccaatagga aagacccagc gaggatgcgg cttcccactg tcctttttcg 367621 acggatgaaa tggctgaacg gttaatttcc gcaatgtagg cggcgctgtt taggctaaag 367681 ccgattaaag cagccgtgac agcggaaaat tcaatgccga tataaggaaa cccgaaataa 367741 aggataaaca aaatcaccaa aatcggaacg cctcgcataa atgagatata gagcttcgcc 367801 ggccatctta acaaagcaag tttagacatt ctggcgagtg atatgaacag gccgatcaca 367861 gttcccgcaa acatgcttac aaaagagatg agcagtgtat aaccaatgcc ttttatgaca 367921 taagggaacg attcaatggc cagcttcgtg ttgaaaatat attcccactg aatgctattg 367981 atcatggcgt ccgattacaa atcaacgtcc tgaacgtcgg catcaatttt ttttgataca 368041 tctgctttat tgaagaattg tttcgacagt ttagtcaaag agccatcctt gctcatctct 368101 ttcaatgctt cgttcatctt tttctgaagt gccgcattgc tttttttcat gacaagggcc 368161 tgtttgttcg gcatgtactt gatgtcagga tgaattgtaa tgttgagatc cgggaatgcc 368221 gcgagcgcaa gtgtctgcag gtaatagtcg tttaaaatga cgtcagtgcg tccgttggca 368281 acatctttta aatattgctc attcgtcgca ttatcataaa tcacttcttt ggcgccgtat 368341 tttctcgcga cctccatgta gacggttgta gccgcgccag ccgctttctt cccttttaaa 368401 tccttgagcg ttttaatccc tgataaatcg tcttttcgga caattgccgt gccgtatgaa 368461 tatttatatg gagtggaaaa tgcgaacttc tcctcacggt ccttcgtcac atcgatgtca 368521 ttcgcggctg cgtcaacctg tccgctgttc accgctgtca gcatcccgtc aatgcccatc 368581 tccttgaact caaccttcag ccccaagcgt tttgccgctt cacgaacaac ttcaacctcg 368641 tagcccgtca gcttatcaga gccagagtca gtatcgtgat aagaagtggg atagagcgta 368701 cctgatgtag cgactacgat tttcccttta tccttaatct gctcccagcc tgtatccttg 368761 gaatcggctt catttttgcc ggaacaggct gccaatataa gaaagaaagc cattgtgaaa 368821 ctgaatataa cggctttgga atgcatgaat gatttcacct atagttcccc caatctgtta 368881 atcaactaaa aagatagcat tgaacataag gggttgcaat atgttgatcg cgttttcaaa 368941 aagttcgaat tgtgtataca aaaagcatgg gtgggtgttt aaaagcgtct atgaagggaa 369001 gaggtgatga aaaaaggaat tgtccaagga tgaatgccag acgtaccaag gaaacgcatg 369061 tgaaagtgaa ggatgcagca gacccgtcac tcatctatgc caataccgga agaaatggtc 369121 aagaggcatg aaaccgatct tcagaataaa tttaagtctt gctgatgccc ctaaggcata 369181 tgatatattc gatgagaaag aaaatggaaa catttaaacc ataatgggga gtcaaatgaa 369241 tatttacaaa ccagccggat tttggatcag acttggagct gcattgttag actacattat 369301 agtctccgtg ccgcttttgc tgatctattg gctgattaca ggaaaagacc caaacgacag 369361 catgttcatc agtttggttg ttctgctgta ttctattttg ctgccgatgt tttggcgcgg 369421 ttatcttatc ggaaaaagga tctgcggaat cagaatcgta aaaaaagacg gatcacaggt 369481 cagtctgtta acaatgtttt tacgggttat tgtagccggc ctggtttact gtataacctt 369541 cggactcggc ttgatcgcca gcctgattct gattgccgta cgagaagaca aacggaccct 369601 gcatgattta atcgcgggaa catatgtcac ttatgcgaca ccaggtgaag aggaacttaa 369661 tgctgacgaa gagattagaa agagcgaata atggttcgct ctttttattt ttatgcataa 369721 aaaatacaag gcagcaaaac atatgaaaaa taggattgga ggaataaaat ggatgaaacg 369781 aataaccatc aacattatca caatgttcat tgcagcggct gtcatttctc tgaccggtac 369841 agctgaggcc gctgaaaaac agcagcagtc tcccgcaaat gttacactga cagatcagca 369901 aaagaaagag attgaacaac tggaagcaga gattcttaaa aagcgcaaag acgtgatctc 369961 aaagtatgta caatacggta tcctgcctaa agaaagagga gaacacatca aaaatcactt 370021 ggacaaacac tttgaaatga tgaaacaaaa cggctttgtt ccaaagcacc atcctcatcc 370081 gcataaattt gaaaaaagac attaagattt taagcatcca atgggaattg ggtgcttttg 370141 cgttatttac aggtaggcaa tattagctga gctgttccgc gactaacatc gagttgatat 370201 gaaacgcgtt tcatagccta tgataggttt atcaaataat tcaggagtga taaacactat 370261 gatccaccag catccagaat cttttccgaa acattttttg tggggctctg cttctgcagc 370321 gtaccagatt gaaggcgctt ggaatgaaga tggcaaaggc ccttctgttt gggatgtgtt 370381 tacgaaaata ccgggcaaaa cgtttaaagg aaccaatggc gagattgcgg ttgaccatta 370441 tcaccgattt aaagaagatg tcgctctgat ggctgagatg gggttaaaag catatcgatt 370501 ttccgtcagc tggccacggg tttttccaaa aggaaaagga gagatcaatg aagcaggtct 370561 agcgttttac gatagtctga ttgatgaatt gctttctcat cacatcgagc cggttctgac 370621 tttatatcac tgggatttgc ctcaagcgct tatggacgaa tacggcgggt ttgaatccag 370681 aaacatcata gaggatttta atcactactg tattactctt tataaacgtt ttggagacag 370741 ggtgaaatat tgggttacgt taaacgaaca gaactacaat tttaatcacg gatttattac 370801 agccatgcat ccgcctggag tgaaagacag aaaacgattt tacgaagcaa accatattgc 370861 gtttctggct aatgcaaaag ccatcgaatc atttagagaa tatgtgcctg aaggcaaaat 370921 aggtcctagc tttgcttatt ctccggctta ccctttatca agtcatccag aggatatact 370981 ggcatttgaa aacgccgaag aatttacgaa caattggtgg cttgacatgt attgctgggg 371041 aacctacccg caaattccat tccgctgctt ggaaaaacag ggatgggcgc cgacaattga 371101 agcaggagat atggacctgc tcgccaaagg gaagcctgat tttgtaggtg tcaattatta 371161 tcagacgatc acctatgaac gaaatccgct tgatggtgtg tcagaaggga aaatgaatac 371221 gacaggccaa aagggaacca atcaggagac ggggataccc ggagtgttca aaacgaaaaa 371281 aaatccgcat ctgacaacga gcaactggga ttggacaatt gacccaattg ggctgcgtat 371341 cggtcttcgc cgaattacaa gccgctatca gcttccagtg tttataacag agaacggttt 371401 gggtgaattt gataaagttg aggacggcac tgtacaggat gattatcgaa ttgattattt 371461 gcgttcgcat cttgagcaat gcagacaagc catcagtgac ggtgtcgatt taatcggcta 371521 ttgcagctgg tcgtttactg atctgttaag ctggctgaac ggctaccaaa aaagatacgg 371581 atttgtatat gtcaatcgtg atgaagaaag cacatccgat ttaaaacgct tgaagaaaaa 371641 aagcttttat tggtatcaag atgtcatcaa gacaaacgga gaaagtttat aaagagtccc 371701 tgagagttat tctctcaggg gtttttcatt acacagaaac agcatcaata atataagtgt 371761 cggcgtgcaa atctgacatt tcagccggca cagtccagca tgtcaattga tagtctcctt 371821 taggcagatc aaaggacagt cttttagaca tgatgctttc aatatgaatt ccgttttctg 371881 tgacatgaaa aggaacagtc actttttttt cgtaggagtt tactgtttct gaactgttca 371941 ggcgaaaaag aataaaggcc tttgtatttc gctgtgcctc aaaggaaatg gctccgtctg 372001 ccgcagcata tcctttttca atcgcttcgt cagtccaatc cattacagga ggtgtagaat 372061 ccttttgaaa tacagtaaat tgatgatatg aaatcgaaag ttcttgcggc ttccatgatt 372121 tgatcaatgt gctgttcctc ctctatgtac tgtttactga attgtgaata aaacctttgt 372181 gccgtctggg taatcggtaa gccgatgccc gacccaagag cctgctccgc ggttgtcagc 372241 gggagaaatg tattctacag aagctccctc accgccttct ttgcacatgg ccattggcca 372301 ttcatctctg tcatacccct ttttggaagg tacgtccttt aatgattgct cgcggcgttc 372361 ttcagctccg tctctgtcaa tagtgcacac ctctgagtgc ccctcattta tcgcatcctt 372421 aatatgcttg gcagtttcgg gataccggtc agatgggaag gccattgttt catcatattc 372481 tttcgtttga gacgtttttt gatcagctga gaaaaagtct ccttttatca ggccgacagc 372541 tgcagctgct atgatgacga tgacgagaag tatcgttttt atgatgtccg tcgtgatgtt 372601 cacctcccgc ttttaaaact gacacaagag taatccagaa agcatttggt gtaaaggttt 372661 aaattttatg ttttacgatc agtttattgc agaaatcgta attttagcag atcgaaatat 372721 ttgttttcag caaaatacga ttgccaattt acaataatga tagtaagtca tcagccgttt 372781 tcggcttgat taatcatttt aaattggctt atgataccgg taagctcctc agctaattga 372841 gaaagtgttt cagaagctgc ggtaatctcc tccattgcag caaattgctc ctctgttaat 372901 gcagccgctt gccgggtatt tttagtagat tctttaatgt cggccgtatt ggctgcaaag 372961 gaatcattta tttgatgtgc actggctgaa atgtttgtta cagatgctga taaatcacta 373021 atctcggcgc tgatttcacc tgttgcagct gcaatttcct taaatgcatc tctggtgcgc 373081 tggatcatgg tgactccttc tgcagcttct gttttcacat gctcaacaga tcttgcagac 373141 cggttcatat ccttttgtat ttctatgatc agttttgaaa tctgccccgc agactgttga 373201 gactcttctg ctaatttccg tacttcatca gcaacaacag caaagccttt tccttgttca 373261 ccggctctgg cagcttcaat cgctgcattc agcgcaagca ggtttgtctg atcagcaatt 373321 tgggtgatga ccgataaaat ttgctcaatt tgtttagagc ggccgtctaa ctggtgtatg 373381 atttctccgc ttttctgaat tgactggtga atcgcatcca tttgcgcctg tacatttgca 373441 atttcctttt gtccaatgtc tgcttttgat tgagcgagct gccctttgtc agcgatagcg 373501 gcagtatttg cagaaatatc ccggatgtct gctgaagctt gttttaatga gctttcacta 373561 ttttcaattc gggtgatctg atcttgggct ccatttgcaa tctgctgtac agcttctgtg 373621 attttttctg aagcttgatt tgtttcctct gctccggctg agagctgctg agaggctgac 373681 gcaagctgaa gggctgattg ttgtacggtt tgtatggtat cgttcagctt cattctcatc 373741 ttattataat agacgcttag ttctgaaagc tcgtcaccgg ttttgtctga cacctctatt 373801 gtcatatctc cgtttccggc actttcaaag gcgcttttta aagcgttcag ccgcttgttg 373861 atttttctgg tgaaaaccaa gacaaggatg actgatacca taatgacgat aacaagaacg 373921 atagcgaatt gagtgaaaag tgattgtgta agtgatgcta aaatactttg attagctccg 373981 gtatacagca tgccgatgat gttcccattt tgatctttta acggcatgta tgcagtctga 374041 taagaagaac ctgctacatc tgcttgtccg taaaaacgct ttcctttctt taaaacagcg 374101 gcaataactt cagaagaagc ctgggtgccg acggctcttt cgccattttt catgacattg 374161 gttgcaacac gagtatcgcc ttggaaaatg gtaatggtat cacctgtctt ttcaccaagc 374221 agatcaacaa tatcttcatt tccattgatt tgtgtttgcc ctttatagag cttattgttt 374281 ttcacctgcc agtcgcctga catgacatca tcaatataag tgctgcttaa agcgagatca 374341 cctttcgctt tttcagttgc catttgtttc atgctttctg taatttcctt aagcatcaca 374401 gtgccaactg atgccgaaaa caaaagaatc accacgaaaa cgaggcaaag aattttagtt 374461 cctagcttca tcttaaatcg ttttatcaac ataattcctc cctttacgat ttgcaggtca 374521 tattacttat cgggtttttg ggtttaaagt tttattttag aaaaaataaa accggcctga 374581 tcttcaggcc ggttgtgtga tgctattcaa ggtttgcgtg gtgagtgaac atagtttcag 374641 aatcgagacc ttttttctcc atgagtttta aaatcactgc atcatagaag agcagcaaag 374701 tttgttcaaa taatgatccc attggctgaa tggttttata gcttccgtta gactggtctt 374761 taggggaacc aggcattctg atgatgaggt ccgcttgttt tccgatgctt gattccggat 374821 tgatggttaa agcggcaaca attccgtgta agctttttgc ttttgctgcg gtatgaatca 374881 agctctttgt ctcgcctgat cctgagccga taataactag atctccttcg gcgagcggcg 374941 gagtgagaat ctcacctact atatgggcgt tgaagcccat gtgcatcagt ctcatcgcga 375001 aggattttgc catcaggcca gaccgccccg cacccgcggt gaaaatttgg tgggatgaaa 375061 gaatgtgatc ggcaagctgg tcagcttctt cattagaaat ataagctgct gaattgtgta 375121 actcattgag aatttccgct acgtattcag tcgttttcat cggagttatc cttggacaat 375181 cagctgcttc atttttgaag ctgtttccgc cttatcagct gcgcttgtaa ttccgccccc 375241 gacaatgaca aggtcaggct tttgctggat cacttctggc agtgtatcaa gtttgatgcc 375301 gcccgcgatt gcggtttttg cgttttttac ggtatttttg attgtcgtta attcttcgaa 375361 agagtttttg ccctctgctt gaagatcata gccagtgtgg acgcagatgt agtcaacacc 375421 gagtgcgtca atttctttcg cacgggattc gatatctttc acgttaatca tgtccactaa 375481 gattttcttc ttttgttttt tggcttcttc tactgcgcct ttaatcgttg catcgtctgt 375541 agcccctaaa acggtgatga tgtcagcgcc tgcttccgac gctttcataa tttcgtagcc 375601 tccggcatcc atgattttca ggtctgcaag aaccttcaat tgaggaaatg cttcttttat 375661 ttctttaacg gctcttaggc cttcattgat gacgaccggt gttccgattt caactacgtc 375721 gatgtattgt tctacctctt tgacaagctc aatggcttcc gggatgttga cgaggtctaa 375781 tgcaagctgt aattccattg ttgatccact ccctttttcg aattattgtt cattctatag 375841 gttccttctt ttgttgagaa gtaggcactt tgaagtcaac aagttacttg gaggatactg 375901 tgaggagaga caatcagatt tctttcgctt gattttatga gtgagtataa tgaaaaaaga 375961 gtctgcaaaa aagtaagtaa gtgatgatac gtatctaaca tacaaaaagg ttactaaggg 376021 gggggattct attgagccgg atggacgaca aaaggtttaa ttgtgagaag gaattaacgc 376081 ttgcagtgat tggcggtaaa tggaaaatgc tcattttatg gcatttagga aaagaaggca 376141 caaaacggtt caatgaatta aaaacattga ttcctgatat tacgcagaag atcctcgtga 376201 atcagctgag agagcttgag caggatatga ttgttcacag ggaagtgtat ccagttgtcc 376261 cgccgaaggt tgaatattct ctgaccccgc acggagaaag cctcatgcct attcttgaag 376321 ccatgtatga gtgggggaaa ggctatatgg aattgattga tatcgacaaa aatgtcatga 376381 aagaatcgtt gtaagacgct cttcgcaagg gtgtcttttt ttgccttttt ttcggttttt 376441 gcgcggtaca catagtcatg taaagattgt aaattgcatt cagcaataaa aaaagattga 376501 acgcagcagt ttggtttaaa aatttttatt tttctgtaaa taatgtttag tggaaatgat 376561 tgcggcatcc cgcaaaaaat attgctgtaa ataaactgga atctttcggc atcccgcatg 376621 aaacttttca cccatttttc ggtgataaaa acattttttt catttaaact gaacggtaga 376681 aagataaaaa atattgaaaa caatgaataa atagccaaaa ttggtttctt attagggtgg 376741 ggtcttgcgg tctttatccg cttatgttaa acgccgcaat gctgactgac ggcagcctgc 376801 tttaatagcg gccatctgtt ttttgattgg aagcactgct ttttaagtgt agtactttgg 376861 gctatttcgg ctgttagttc ataagaatta aaagctgata tggataagaa agagaaaatg 376921 cgttgcacat gttcactgct tataaagatt aggggaggta tgacaatatg gaaataactt 376981 tttacccttt aacggatgca caaaaacgaa tttggtacac agaaaaattt tatcctcaca 377041 cgagcatttc aaatcttgcg gggattggta agctggtttc agctgatgcg attgattatg 377101 tgcttgttga gcaggcgatt caagagttta ttcgcagaaa tgacgccatg cgccttcggt 377161 tgcggctaga tgaaaacggg gagcctgttc aatatattag cgagtatcgg cctgttgata 377221 taaaacatac tgacactact gaagatccga atgcgataga gtttatttca caatggagcc 377281 gggaggaaac gaagaaacct ttgccgctat acgattgtga tttgttccgt ttttccttgt 377341 tcaccataaa ggaaaatgaa gtgtggtttt acgcaaatgt tcatcacgtg atttctgatg 377401 gtatctccat gaatattctc gggaatgcga tcatgcacat ttatttagaa ttagccagcg 377461 gctcagagac aaaagaagga atctcgcatt catttatcga tcatgtttta tctgaacagg 377521 aatatgctca atcgaagcgg tttgaaaagg acaaggcgtt ttggaacaaa caatttgaat 377581 cggtgcctga acttgtttcc ttgaaacgga atgcatccgc agggggaagt ttagatgctg 377641 agaggttctc taaagatgtg cctgaagcgc ttcatcagca gattctgtcg ttttgtgagg 377701 cgaataaagt cagtgttctt tcggtatttc aatcgctgct cgccgcctat ttgtacaggg 377761 tcagcggcca gaatgatgtt gtgacgggaa catttatggg caaccggaca aatgcgaaag 377821 agaagcagat gcttggcatg tttgtttcta cggttccgct tcggacaaac attgacggcg 377881 ggcaggcgtt ttcagaattt gtcaaagacc ggatgaagga tctgatgaag acacttcgcc 377941 accaaaagta tccgtataat ctcctaatca acgatttgcg tgaaacaaag agctctctga 378001 ccaagctgtt cacggtttct cttgaatatc aagtgatgca gtggcagaaa gaagaggatc 378061 ttgccttttt gactgagccg attttcagcg gcagcggatt aaatgatgtc tcaattcatg 378121 taaaggatcg atgggatact gggaaactca ccatagattt tgattaccgc actgatttat 378181 tttcacgtga agaaatcaac atgatttgtg agcgcatgat taccatgctg gagaacgcgt 378241 taacgcatcc agaacataca attgatgaat taacactgat ttctgatgcg gagaaagaga 378301 agctgcttgc gagggccggc ggtaaatctg tgagctaccg taaggacatg acgataccag 378361 agctgttcca agaaaaggct gaactgcttt ctgatcatcc agcggttgta tttgaagatc 378421 gcacattgtc ctatcgaacg ttacatgagc aatctgcacg catcgccaat gtgctgaaac 378481 agaaaggggt tggcccggac agtcctgtcg cggttttgat tgaacgctct gaacggatga 378541 ttacagctat catgggaatt ttaaaagccg gcggagccta tgtgccgatt gatccgggtt 378601 ttcctgctga gcgcattcaa tatattttgg aggactgcgg ggcggatttc atcctgactg 378661 aatcgaaggt tgcggcgcct gaagccgatg ctgagctgat tgacttagat caggcgattg 378721 aggaaggtgc agaagaaagc ctgaatgcag atgtgaacgc tcggaacctt gcctacatta 378781 tttacacatc gggaacaacc ggacgcccga aaggcgttat gatcgagcat cgccaggttc 378841 atcatttggt tgaatctctg cagcagacga tttatcaaag cggcagccaa accctgcgga 378901 tggcattgct tgcgccgttc cactttgatg cgtcagtgaa gcagatcttc gcgtcgcttc 378961 ttttgggcca aaccctttat atcgtaccga agaaaacagt gacgaacggg gccgccctta 379021 ctgcatatta tcggaagaac agcattgagg cgacggacgg aacaccggct catttgcaaa 379081 tgctggcagc agcaggcgat tttgaaggcc taaaactgaa gcacatgctg atcggaggag 379141 aaggcctgtc atctgttgtt gcggacaagc tgctgaagct gtttaaagaa gccggcacag 379201 cgccgcgttt gactaatgtg tacgggccga ctgaaacgtg cgttgacgcg tctgttcatc 379261 cggttatccc tgagaatgca gttcaatcag cgtatgtgcc gatcgggaaa gcgctgggga 379321 ataaccgctt atatattttg gatcaaaaag gccggctgca gcctgaaggc gtggcgggtg 379381 agctttatat cgcgggagac ggtgtgggcc gaggctattt acatttgcct gaattaacgg 379441 aagagaagtt tttacaagat ccattcgtgc cgggcgatcg catgtaccgg accggggacg 379501 tggtgcgctg gcttccagat ggaacaatcg aatatttagg cagagaggat gaccaggtca 379561 aagtccgcgg ataccggatt gagcttgggg aaattgaagc cgtgattcag caggcgccag 379621 acgttgcaaa agccgttgtt ttggcacgcc ctgacgaaca gggaaatctt gaggtttgcg 379681 catatgttgt gcagaagcct ggaagcgaat ttgcgccagc cggtttgagg gagcatgcgg 379741 ccagacagct tcctgactat atggtgccgg cttactttac agaagtgaca gaaattccgc 379801 ttacaccaag cggcaaagtc gaccgccgca agctgtttgc actagaggtg aaggctgtca 379861 gcggcactgc ctatacagcg ccgcgaaatg agactgaaaa agcaatcgca gccatttggc 379921 aggacgtgct gaacgttgag aaggcgggga tctttgacaa tttctttgaa actggcggac 379981 attcattaaa agccatgacc cttttaacaa agattcataa ggaaacaggc attgagattc 380041 cgcttcaatt tttgtttgag catccgacga ttacggctct tgcagaggaa gctgatcaca 380101 gagaaagcaa agcttttgcg gtgattgaac ctgctgaaaa acaggagcat tacccgcttt 380161 cattggcaca gcagcgaaca tatatcgtca gccagttcga ggatgcggga gtcggctata 380221 acatgccagc agcagcaatt ctggaagggc ctttagatat tcaaaagctg gagcgcgcat 380281 ttcagggatt aatccgacgc cacgagtcat tgagaacatc atttgttctt gaaaacagca 380341 cgccgagaca gaaaattcac gatagcgttg atttcaacat cgaaatgatt gaaagaggcg 380401 gccgctcaga tgaggcaatt atggcttcat tcgttcggac atttgatttg gcgaaagctc 380461 cgctgttcag aatcggtttg ctggggcttg aagagaaccg tcatatgctg ctgtttgaca 380521 tgcaccattt gatttctgac ggtgtatcca ttggcattat gctggaggag ttagcacgca 380581 tttataaagg cgaacagctt cctgatcttc gtctccagta taaggactac gctgtatggc 380641 aaagcagaca ggctgctgaa gggtacaaga aggaccaggc ttattggaag gaagtctttg 380701 caggcgagct cccggtgctt cagcttctgt ccgattaccc aagaccacct gttcaaagct 380761 ttgaagggga tcgggtgtca atcaagctgg atgcgggggt aaaggatcgc ctcaatcgtt 380821 tggctgaaca aaacggcgcc actttatata tggtgatgct ttccgcttac tatacgcttt 380881 tgtcaaagta tacggggcag gatgacatca ttgtcgggac accgtcagcg ggcagaaatc 380941 actccgatac agagggcatt atcgggatgt tcgtcaatac gcttgcgatt cgcagtgagg 381001 tgaagcagaa tgagacgttt acccaattga tctcgcgtgt ccgcaaacgg gtgctggatg 381061 ccttttctca tcaggactat ccgtttgagt ggcttgttga agatttgaac atcccgcgtg 381121 atgttagcag gcatccgctg tttgacacga tgttcagcct tcaaaacgcg acagagggca 381181 ttccggctgt cggcgatctt tccttgtctg ttcaagagac caatttcaag attgccaaat 381241 ttgatttgac ggtgcaggcg agagaaaccg atgaaggcat tgagattgat gtggattaca 381301 gcacaaagct gtttaaacaa agcacggcag acaggctgct tacgcatttt gcgcgtttgc 381361 ttgaagatgc tgcggctgat ccagagaagc cgatttctga gtataagctt ctttctgaag 381421 aggaggctgc ttcgcaaatt cagcagttta acccgggcag aacaccttat ccgaaagata 381481 aaacaattgt tcagctgttt gaggagcaag cggcgaatac gccagaccac actgcgcttc 381541 aatatgaagg cgaatcactc acttatcgtg aactgaatga acgggccaat cgtttagccc 381601 gcggcattct ttctcttgga gctggcgaag gcagaactgc ggctgtctta tgcgagcggt 381661 caatggatat gattgtgtcg atcttggcag tattaaaatc aggttcggct tatgttccga 381721 tcgatccgga acatccgatt cagcggatgc agcatttctt ccgtgacagc ggagcaaagg 381781 tgcttctcac tcagaggaaa ttaaaggctt tggcggaaga agcggaattt aagggcgtta 381841 tcgtgctagc cgatgaggaa gaaagctatc atgccgatgc gcgaaatctc gcactgcctc 381901 ttgattctgc agcaatggcc aacctgacgt atacttccgg aacgactgga acacctaagg 381961 ggaatatcgt gacacatgcc aatattctcc gcacggtgaa ggaaacgaat tatctcagca 382021 ttacagaaca ggatacgatt ctcggtcttt ccaattacgt gtttgacgcg tttatgttcg 382081 atatgttcgg ctctttgtta aacggagcca agctggtgct gataccgaag gaaaccgttt 382141 tggacatggc tcgcctgtcc cgcgtcattg aacgggagaa catcagcatt ctcatgatta 382201 caaccgcttt gttccacttg cttgtggact tgaatccggc atgcttgtca acgcttcgca 382261 agattatgtt tggcggggaa cgggcttcgg ttgagcatgt cagaaaagct ttgcaaacgg 382321 ttggaaaggg caagctcctt catatgtatg gaccgtctga aagcacggtt ttcgcgacgt 382381 atcatccggt tgatgaattg gaggagcaca cgctgtctgt tccgattgga aaaccggtca 382441 gcaatacgga agtatacatt cttgaccgta cgggacacgt gcagcctgcc gggattgccg 382501 gagagctttg cgtcagcggc gaaggactcg tgaaaggcta ttacaaccgt ccagaactga 382561 ctgaggagaa atttgttccc catccgttta catccggcga acgcatgtat aaaacgggag 382621 accttgcgag atggctgccg aatggcgaca tcgaatttat cgggcgaatc gaccatcagg 382681 tgaagattcg cggacagcgc atcgagcttg gagaaatcga acatcagctg caaacccatg 382741 atcgtgttca ggaaagtgtt gtgcttgccg ttgatcaagg agcgggagat aaactgttgt 382801 gtgcttacta tgtcggagaa ggagacatct catcacaaga gatgagagag catgctgcga 382861 aggacttgcc ggcatatatg gttcctgcgg tgtttatcca aatggacgag ctgccgctga 382921 cagggaacgg aaaaattgac cggagagcgc tgccgattcc tgatgccaac gtttcaagag 382981 gtgtttcata tgttgcgcca cgcaatggaa cggaacaaaa agtcgcggac atttgggcac 383041 aggtacttca ggcagaacaa gtcggcgctt atgaccactt ctttgacatt ggcggacatt 383101 cattagcagg catgaagatg cttgccttgg ttcatcagga actgggcgtt gagctgtcac 383161 tcaaggatct cttccagtca ccgacggttg agggcttggc acaggtgatt gcctctgctg 383221 aaaaagggac agccgcaagt atcagcccgg cagagaaaca agatacgtat cctgtttctt 383281 caccgcaaaa acggatgtac gtgcttcagc agcttgagga tgcgcaaacg agctataaca 383341 tgccggcggt tctgcgcctg acaggtgagc ttgatgttga aaggcttaac agcgtcatgc 383401 agcagttaat gcagcgtcat gaagccttga gaaccacgtt tgaaataaaa gatggagaaa 383461 cggtgcagcg gatctgggaa gaggctgagt gcgagatagc ctatttcgaa gccccggaag 383521 aagagacaga gcggatcgtt tctgagttta ttaagccttt caaaatcgac caacttccac 383581 tgttcagaat agggcttatc aagcattcag acactgagca tgtgctgctg ttcgatatgc 383641 atcatattat ttctgatggt gcatctgtcg gtgtgctgat tgaggagctt tcaaagctgt 383701 acgacggaga aacccttgag ccgctccgta ttcaatataa ggattatgcc gtgtggcagc 383761 agcagttcat tcagtctgag ctttacaaga agcaagaaga gcattggctg aaggagctgg 383821 acggagagct gccggtgctg acgcttccga ctgattacag tcggcctgcc gttcaaacat 383881 ttgagggaga ccgcattgca ttttcattag aagcaggcaa agctgatgct ctgcgcaggc 383941 ttgcaaaaga aacggattcc acgctttaca tggtgcttct ggcttcatac agtgcgtttt 384001 tatcaaaaat tagcgggcaa gacgatatca tcgtcggttc acctgtggcc ggacgatctc 384061 aagcggacgt cagccgcgtc atcggaatgt tcgtcaatac attggcgctg cgcacgtatc 384121 cgaagggtga aaagacgttt gctgactatc ttaacgaagt gaaagaaacg gcactcagcg 384181 cttttgatgc gcaggattac ccacttgagg atttgatcgg aaatgttcag gttcagcgtg 384241 acacaagcag aaatccgtta ttcgatgcag ttttttcaat gcaaaatgcg aatataaagg 384301 atttaacaat gaaagggatt cagcttgagc cgcatccgtt tgaacggaaa acagccaagt 384361 ttgacctcac gctgacggct gacgaaaccg acggagggct tacattcgta ctcgaataca 384421 atacagctct gtttaagcag gaaacgattg aacgatggaa gcaatattgg atggagcttt 384481 tagatgcagt tactgggaac ccgaaccagc cgctttccag cctgtcactg gtcaccgaga 384541 cagaaaagca agcgcttctt gaggcatgga agggcaaagc gctgcctgtg ccgacagaca 384601 aaacggttca tcagctattc gaagagactg cccagcgcca caaagaccgc ccggctgtca 384661 catacaacgg ccagtcttgg acgtacggcg agctgaatgc gaaggcaaac cgtctcgcgc 384721 ggattctgat ggactgcggc atcagcccgg atgaccgcgt cggcgttctc acgaagccgt 384781 cgcttgaaat gtccgccgcg gtgctcggcg tcttgaaagc cggagcggcg tttgtgccga 384841 ttgatcctga ctatccggat cagcggattg agtatatttt acaggacagc ggcgcgaagc 384901 ttctcttgaa acaggaaggc atttcagtgc cggacagcta tacgggagat gtcattcttc 384961 tcgacggaag ccgcacgatt ctaagcctgc cgcttgatga aaacgacgag gaaaatccag 385021 aaaccgctgt aaccgcggag aacttggcgt acatgattta cacgtctgga acgaccggac 385081 agccgaaggg tgtcatggtc gagcaccatg cgcttgtgaa cctgtgcttc tggcaccacg 385141 acgcgttcag catgacagcg gaggaccgca gtgcgaagta cgcgggcttt gggttcgacg 385201 cttccatttg ggagatgttc ccgacctgga cgatcggtgc cgaacttcac gtcattgagg 385261 aagcgatccg cctcgatatc gtccgcctga acgattattt tgaaacgaac ggcgtaacga 385321 tcacgttcct gccgacacag cttgcggaac agttcatgga gcttgagaac acatcacttc 385381 gcgtattgct tactggagga gacaagctga agcgcgcagt gaaaaagccg tacacactcg 385441 tcaataacta cgggccgaca gagaatacgg tcgttgccac aagcgcagaa atccatccgg 385501 aggaaggctc gctttccatc ggaagggcca ttgccaatac gagagtatac attctcggcg 385561 agggcaatca ggtgcagccg gaaggcgtag ccggagagct ttgcgtggcg gggcgcggac 385621 tggcacgcgg ctatctgaat cgagaagacg aaaccgcgaa gcggtttgtc gctgatccgt 385681 ttgtgccggg tgagcgcatg taccgcaccg gcgatttggt gaaatggacg ggcggcggca 385741 tcgaatacat cggccggatc gaccagcagg tcaaggtccg cggctaccgg atcgagctct 385801 cagaaattga agtccagctc gcccagcttt ctgaggtgca ggatgcggcg gtgacagctg 385861 tcaaagataa aggcggcaac acagcgatcg cggcgtatgt cacaccggaa tcagctgaca 385921 tagaagcact gaaatcagca ctgaaggaaa ccctgccgga ttacatgatc ccggcgttct 385981 gggtgacgct gaacgagctt ccggttacgg caaacggcaa agtggaccgc aaagccttgc 386041 ctgagccgga catcgaagcg ggaagcggag aatacaaagc gccgacgacc gacatggaag 386101 agctgcttgc cggcatctgg caggacgtgc ttggaatgtc tgaagtcggt gtcaccgaca 386161 atttcttctc gcttggcgga gattccatca aaggaattca aatggcgagc cgcttgaacc 386221 agcacggctg gaagctggaa atgaaagatc tcttccagca cccgacgatc gaagagctca 386281 cccagtacgt agagcgtgcc gaaggcaaac aggcagacca aggcccggtg gagggcgaag 386341 tcatcctgac gccgatccag cgctggttct ttgaaaagaa cttcacgaac aagcaccact 386401 ggaaccaatc tgtgatgctt cacgccaaga agggctttga tcctgaacgg gtggagaaaa 386461 cattgcaggc gctgatcgag catcatgacg cgctccgcat ggtctatcgt gagggacagg 386521 aagacgtcat tcaatacaac agaggtcttg aagctgcttc agctcaattg gaggtcatcc 386581 agattgaggg ccaagctgca gattacgaag accgaataga gagagaagcg gagcgtttgc 386641 aaagcagcat cgacttgcag gaaggcggct tgttaaaagc aggcttgttc caagcggaag 386701 acggagatca cttgcttctt gccattcacc acttagtggt tgacggcgtg tcgtggcgga 386761 ttttactgga ggatttcgcc gcggtatata cacagcttga gcaaggcaat gaaccggttc 386821 tcccgcagaa aacacattca tttgcagagt atgcagagag attgcaagac ttcgcgaact 386881 ccaaagcctt tttgaaagaa aaagagtatt ggagacagct tgaagaacaa gctgttgcgg 386941 caaagcttcc gaaagaccgc gaatctggtg atcagcgaat gaaacataca aagacaattg 387001 aattctcgct gactgctgaa gagacagaac agctcaccac aaaggtgcat gaggcatatc 387061 acacagaaat gaatgatatt ttgctgacgg cattcggatt ggcaatgaag gagtggacgg 387121 gtcaagatcg agtaagtgtt catttagagg ggcatggacg tgaagaaatc atagaagacc 387181 tgaccatttc tcgcacagtc ggctggttta caagtatgta cccaatggtg ctcgatatga 387241 agcatgcgga tgatctgggc taccagctga agcaaatgaa agaagatatc agacatgtgc 387301 cgaataaggg agtcggatac ggcattctgc gctatctgac ggcaccggaa cataaagaag 387361 atgtggcgtt ctcgattcag ccggatgtca gcttcaacta tttaggtcag tttgacgaaa 387421 tgtcggatgc aggtttgttt acgagatcag agctgccatc aggacagtca ttaagccctg 387481 aaacagaaaa accgaatgcg ctggatgttg tcggatatat cgaaaacgga aaactgacga 387541 tgtcactggc ctatcattct cttgaatttc atgaaaaaac agtacaaaca ttcagtgaca 387601 gctttaaagc gcatcttctc agaatcattg aacattgcct atctcaagat ggtacggaac 387661 tgaccccgag tgatcttggt gacgacgatt tgacgctgga tgagctggat aaattaatgg 387721 aaattttcta atagaggtgg catatgagca aaaaatcgat tcaaaaggtg tacgcactga 387781 caccaatgca ggagggaatg ctgtatcatg cgatgcttga tccgcattct tcctcgtact 387841 tcacacaatt agagcttggg attcacggcg cttttgatct tgaaatcttt gagaaaagcg 387901 tcaatgaact gattcggtca tacgatattc tccgtacggt atttgtgcat cagcagctgc 387961 aaaaaccgcg tcaggtcgtg ttagcggaac gcaaaacaaa agtgcattat gaggatatca 388021 gtcatgcaga cgaaaaccgc cagaaagagc acattgagcg ttacaaacaa gacgttcagc 388081 gccaaggctt taacctggca aaagacatat tgttcaaggt agcggttttc cgccttgctg 388141 cagatcagct gtatcttgtc tggagcaatc atcatattat gatggacggc tggagcatgg 388201 gcgtcctcat gaaaagcctg ttccaaaact atgaagcgct cagagcaggc aggacaccgg 388261 caaacggtca gggcaagcct tattccgatt acatcaagtg gcttggaaaa caggacaatg 388321 aagaagcgga gagctactgg agcgagcgct tggcgggttt tgaacagcca agcgtgctcc 388381 cgggccgcct gcctgtgaaa aaagacgaat acgtcaataa agaatattca tttacatggg 388441 acgaaacact ggttgcccgt attcagcaaa ccgcaaatct ccatcaagtg acagggccta 388501 acctatttca ggccgtttgg ggcattgttc tcagcaaata caactttacg gatgatgtga 388561 tcttcggaac ggtcgtctcg ggacgaccgt ctgaaatcaa cggaatcgaa acgatggcgg 388621 ggctgtttat caacaccatt ccagtgcggg tgaaagttga acgagatgct gcattcgctg 388681 atattttcac agctgttcag cagcatgcag tagaggcaga gcgttacgat tacgtgccgc 388741 tctatgagat tcaaaaacgc tcagctcttg atggcaatct cttaaaccat ctggtcgcgt 388801 ttgaaaatta tccgcttgat caagagcttg aaaacggcag catggaagac cgcctcgggt 388861 tttcgattaa ggtagaaagc gcatttgaac aaacgagctt cgatttcaac ctgattgtgt 388921 atccgggcaa aacgtggacc gtcaaaatta aatataacgg agccgccttt gattccgctt 388981 ttatcgaacg gacagcggag caccttaccc gcatgatgga agcagctgtc gatcagccgg 389041 ccgcttttgt gcgtgagtac gggcttgtgg gagacgaaga gcagcggcaa attgtcgagg 389101 tgtttaacag cacgaaagcc gaactccctg aaggaatggc tgttcaccaa gtgtttgaag 389161 agcaagcgaa acggacgccg gcgagcaccg ccgtcgtata tgaaggaacc aagctgacgt 389221 accgcgagct gaatgcagcg gctaaccgtc tggcgagaaa gcttgtcgaa catgggcttc 389281 aaaaagggga aacagcagcg attatgaacg accgctcagt agaaaccgtt gtcggcatgc 389341 tggctgtttt aaaagcaggc gccgcatatg tgccgcttga tccagcgctt cctggggatc 389401 gtcttcgttt catggcagag gacagctccg ttcgaatggt tttgatcgga aattcttata 389461 cagggcaggc acatcagctg caagtgccgg ttcttacact ggacataggc tttgaagaga 389521 gtgaagcggc tgacaatctc aacctgccat ccgccccgtc tgatttggcg tacatcatgt 389581 acacatccgg ttcaacgggc aaaccgaaag gcgtcatgat cgaacataaa agcattctgc 389641 gcctcgtcaa aaatgccggg tacgttcctg ttactgaaga agaccgcatg gcgcaaacgg 389701 gagctgtcag ctttgatgcc ggaacgtttg aggtattcgg cgcactgctg aatggcgcag 389761 cactttatcc ggtcaaaaaa gagacactgc ttgatgcgaa acaatttgct gcattcctgc 389821 gtgagcaaag catcacaact atgtggctga catcaccttt attcaaccag cttgctgcaa 389881 aggatgcggg tatgttcggc acactgcgcc atttaatcat cggcggagat gcccttgtcc 389941 cgcatattgt cagcaaagta aaacaggcat cgccgtcgct ttcattgtgg aacggatacg 390001 gcccgacaga aaacacgacg ttttcaacca gttttctgat cgaccgcgag tatggcggct 390061 ctatcccaat cgggaagccg atcggaaatt ccactgccta tattatggat gagcagcaat 390121 gcctgcagcc aatcggcgcg cctggtgagc tttgcgtagg cggaatcggt gtagcgcgtg 390181 ggtatgtcaa tctccctgag ctgacggaga agcaatttct ggaagacccg ttcagaccgg 390241 gtgagagaat ttaccgcact ggtgacttgg caagatggct gccggacggc aatatcgaat 390301 ttttaggcag aatcgacaac caagtgaagg tgcgcggctt ccgaattgag cttggcgaaa 390361 ttgaaacaaa actgaacatg gctgagcatg tgacagaagc cgcggtgatc atacgcaaga 390421 acaaagcaga cgaaaatgaa atttgcgcgt acttcacggc ggatcgtgaa gtggctgtga 390481 gtgagctgag aaaaacactg tctcagtctt tgcctgacta tatggtccct gcccacctga 390541 ttcaaatgga cagcctgccg ctcacgccaa acgggaaaat caacaaaaag gaactgcctg 390601 caccgcaatc agaagccgtg cagccggaat acgcagcacc aaaaacagag agtgaaaaga 390661 aattagcgga gatctgggaa ggaatactcg gcgtcaaagc aggcgttacc gataacttct 390721 ttatgatcgg cggccattct ttgaaagcga tgatgatgac ggcgaaaatt caagagcatt 390781 ttcataagga agttccgata aaagtgcttt ttgaaaagcc gactattcaa gaactggcac 390841 tgtatttgga agagaacgaa agcaaggagg agcagacgtt tgaaccgatc aggcaagcat 390901 cttatcagca gcattatcct gtatccccgg cccagcggag aatgtatatc ctcaatcagc 390961 ttggacaagc aaacacaagc tacaacgtcc ccgctgtact tctgctggag ggagaagtag 391021 ataaagaccg gcttgaaaac gcgattcagc aattaatcaa ccggcacgaa atcctccgta 391081 catcgtttga catgatcgac ggagaggttg tgcaaaccgt tcataaaaac atatcgttcc 391141 agctggaggc tgccaaggga cgggaagaag acgcggaaga gataatcaaa gcatttgttc 391201 agccgtttga attaaaccgc gcgccgctcg tccgttcgaa gcttgtccag ctggaagaaa 391261 aacgccacct gctgctcatt gatatgcatc atattattac tgacggaagt tcaacaggca 391321 ttctaatcgg tgatcttgcc aaaatatatc aaggcgcaga tctggaactg ccacaaattc 391381 actataaaga ttacgcagtt tggcacaaag aacaaactaa ttatcaaaaa gatgaggaat 391441 actggctcga tgtctttaaa ggcgaactgc caatactgga tcttcccgcg gatttcgagc 391501 ggccagctga acggagcttt gcgggagagc gcgtgatgtt tgggcttgat aagcaaatca 391561 cggctcaaat caaatcgctc atggcagaaa cagatacgac aatgtacatg tttttgctgg 391621 cggcgttcaa tgtactcctt tccaagtacg cgtcacagga tgatatcatt gtcggctcgc 391681 cgacagctgg cagaacacat cctgatctgc aaggtgtgcc gggtatgttt gtcaacacgg 391741 tggcactcag aacggcacca gcgggagata aaaccttcgc gcaattcctt gaagaggtca 391801 aaacagccag ccttcaagca ttcgagcacc agagctatcc gcttgaggag ctgattgaaa 391861 agcttccgct tacaagggat acaagcagaa gtccgctgtt cagcgtgatg ttcaacatgc 391921 agaatatgga gattccttca ttaagattag gagatttgaa gatttcctcg tattccatgc 391981 ttcatcatgt tgcgaaattt gatctttcct tggaagcggt cgagcgtgaa gaggatatcg 392041 gcctaagctt tgactatgcg actgccttgt ttaaggacga gacgatccgc cgctggagcc 392101 gccactttgt caatatcatc aaagcggccg cggctaatcc gaacgttcgg ctgtctgatg 392161 tagatctgct ttcatctgca gaaacggctg ctttgctaga agaaagacat atgactcaaa 392221 ttaccgaagc aacctttgca gcactttttg aaaaacaggc ccagcaaaca cctgaccatt 392281 ctgcggtgaa ggctggcgga aatctgttga cctatcgcga gcttgatgaa caggcgaacc 392341 agctggcgca tcatcttcgt gcccaagggg caggaaatga agacatcgtc gcgattgtta 392401 tggaccggtc agctgaagtc atggtatcca ttctcggtgt catgaaggcg ggggcagctt 392461 tccttccgat tgatcctgat acacctgaag aacgaatccg ttattcatta gaggacagcg 392521 gagcaaaatt tgcggtcgtg aatgaaagaa acatgacggc tattgggcaa tatgaaggga 392581 taattgtcag ccttgatgac ggtaaatgga gaaatgaaag caaggagcgc ccatcatcca 392641 tttccgggtc tcgcaatctt gcatacgtca tttatacgtc cggtacgacc ggaaagccaa 392701 agggcgtgca gattgagcat cgtaatctga caaactatgt ctcttggttt agtgaagagg 392761 cgggcctgac ggaaaatgat aagactgtat tgctttcatc ttacgcattt gaccttggct 392821 atacgagcat gttccctgta cttctgggcg ggggcgagct ccatatcgtc cagaaggaaa 392881 cctatacggc gccggatgaa atagcgcact atatcaagga gcatgggatc acttatatca 392941 agctgacacc gtctctgttc catacaatag tgaacaccgc cagttttgca aaagatgcga 393001 actttgaatc cttgcgcttg atcgtcttgg gaggagaaaa aatcatcccg actgatgtta 393061 tcgccttccg taagatgtat ggacataccg aatttatcaa tcactacggc ccgacagaag 393121 caacgatcgg cgccatcgcc gggcgggttg atctgtatga gccggatgca tttgcgaaac 393181 gcccgacaat cggacgcccg attgcgaatg ccggtgcgct tgtcttaaat gaagcattga 393241 agcttgtgcc gcctggagcg agcggacagc tctatatcac gggacagggg ctcgcgagag 393301 ggtatctcaa caggcctcag ctgacagccg agagatttgt agaaaatcca tattcgccgg 393361 gaagcctcat gtacaaaacc ggagatgtcg tacgaagact ttctgacggt acgcttgcat 393421 ttatcggccg ggctgatgat caggtgaaaa tccgaggcta ccgcattgag ccgaaagaaa 393481 ttgaaacggt catgctcagc ctcagcggaa ttcaagaagc ggttgtacta gcggtttccg 393541 agggcggtct tcaagagctt tgcgcgtatt atacgtcgga tcaagatatt gaaaaagcag 393601 agctccggta ccagctttcc ctaacactgc cgtctcatat gattcctgct ttctttgtgc 393661 aggttgacgc gattccgctg acggcaaacg gaaaaaccga cagaaacgct ctgccgaagc 393721 ctaacgcggc acaatccgga ggcaaggcct tggccgcacc ggagacagcg cttgaagaaa 393781 gtttatgccg catttggcag aaaacgcttg gcatagaagc catcggcatt gatgacaatt 393841 ttttcgattt aggcggccat tcattaaaag ggatgatgct gattgccaac attcaggcgg 393901 aattggagaa aagcgtaccg cttaaagcac tgttcgagca gccgacagtt cgccagctgg 393961 cggcttatat ggaggcgtct gctgtttcag gcggccatca agtactcaaa ccggctgaca 394021 agcaggatat gtatccattg tcatccgcac agaaacgaat gtacgtgctc aatcagcttg 394081 accgccagac gataagctac aacatgccat ctgttcttct aatggaagga gagcttgata 394141 tttcgcgcct gcgcgactca ctcaatcagc ttgtgaaccg tcacgaatca ttgcggacgt 394201 catttatgga agctaatggt gagcctgttc agcgcatcat tgagaaggcg gaggttgatc 394261 ttcatgtgtt tgaagccaaa gaagacgaag cggaccaaaa gattaaggaa tttatccggc 394321 cattcgactt aaacgacgca ccgctcattc gcgcagcttt gcttcgaata gaagcgaaaa 394381 aacatttgct gcttttagat atgcatcata tcatcgcaga cggcgtctca agaggcatct 394441 ttgtaaaaga attggcgctg ctttacaaag gagagcagct tccggagccg acgcttcatt 394501 ataaagattt cgccgtttgg caaaatgaag ctgagcaaaa agaacggatg aaggagcatg 394561 aggcgtactg gatgtcagtt ctttcaggcg agctgccaga gcttgatctc ccgctcgatt 394621 atgcccgtcc gcctgtgcaa agctttaaag gagatacgat ccgtttccgt acgggaagtg 394681 agacggcaaa ggcggtagaa aaactgcttg ccgaaaccgg aacgaccttg cacatggtgc 394741 tccatgctgt tttccacgtc tttttaagca aaatttccgg acagcgggat atcgtcatcg 394801 gctccgttac tgccggccgg acgaatgctg atgttcagga catgccggga atgttcgtca 394861 atacacttgc cctgagaatg gaagcgaaag aacagcaaac atttgcggag cttttggagc 394921 tagcaaagca gacgaacctg tcagcccttg agcatcagga gtatccgttt gaagatctgg 394981 ttaatcagct tgatctccct cgggatatga gccgaaaccc attgtttaat gtgatggtga 395041 cgacagaaaa ccctgataaa gaacagctta cattgcaaaa tctgagcatt tcaccttatg 395101 aggctcatca gggaacttct aagtttgatc tgacactggg cggatttact gatgaaaatg 395161 gcattggctt gcagctcgaa tatgcgacag atctgttcgc aaaagaaaca gctgaaaaat 395221 ggagcgaata cgttctgcgg ctactaaagg ctgttgcgga taacccgaac cagccgcttt 395281 ccagtctgtt actggtcacc gagacagaaa agcaagcgct tcttgaggca tggaagggca 395341 aagcgctgcc tgtgccgaca gacaaaacgg ttcatcagct attcgaagag actgtccagc 395401 gccacaaaga ccgcccggct gtcacataca acggccaatc ttggacgtac ggcgagctga 395461 acgcgaaggc aaaccgcctc gcccggattc tgatggactg cggcatcagc ccggatgacc 395521 gcgtcggcgt tctcacgaag ccgtcgcttg aaatgtccgc cgcggtgctc ggcgtcttga 395581 aagccggagc ggcgtttgtg ccgattgatc ctgactaccc ggatcagcgg attgagtata 395641 ttttacagga cagcggcgcg aagcttctct tgaaacagga aggcatttca gtgccggaca 395701 gctatacggg agatgtcatt cttctcgacg gaagccgcac gattctaagc ctgccgcttg 395761 atgaaaacga cgagggaaat ccagaaaccg ctgtaaccgc ggagaacttg gcgtacatga 395821 tttacacgtc tggaacgacc ggacagccga agggtgtcat ggtcgagcac catgcgcttg 395881 tgaacctgtg cttctggcac cacgacgcgt tcagcatgac agcggaggac cgcagtgcga 395941 agtacgcggg cttcgggttc gacgcttcca tttgggagat gttcccgacc tggacgatcg 396001 gcgctgaact tcacgtcatt gatgaagcga tccgcctcga tatcgtccgc ctgaacgatt 396061 attttgaaac gaacggcgta acgatcacgt tcctgccgac acagcttgcg gaacagttca 396121 tggagcttga gaacacatca cttcgcgtcc tcttgaccgg aggagacaag ctgaagcggg 396181 cagtgaaaaa gccgtacaca ctcgtcaaca actacgggcc gacagaaaat acggtcgttg 396241 ccacaagcgc agaaatccat ccggaggaag gctcgctttc catcggacgg gccattgcca 396301 atacgagagt atacattctc ggcgagggca atcaggtgca gccggaaggc gtagccggag 396361 agctttgcgt ggcggggcgc ggactggcac gaggctatct gaatcgagaa gacgaaaccg 396421 cgaagcggtt tgtcgctgat ccgtttgtgc cgggtgaacg catgtaccgc accggcgact 396481 tggtgaagtg ggtgaacggc ggcatcgaat acatcggccg gatcgaccag caggtcaagg 396541 tccgcggcta ccggatcgag ctctcagaaa ttgaagtcca gctcgcccag ctttctgagg 396601 tgcaggatgc ggcggtgaca gctgtcaaag ataaaggcgg caatacagcg atcgcggcgt 396661 atgtcacacc ggaaacagct gacatagaag cactaaaatc aacactaaag gaaaccctgc 396721 cggattacat gatcccggcg ttctgggtga cgctgaacga gcttccggtt acggcaaacg 396781 gcaaagtcga ccgcaaagcc ttgcctgagc cggacatcga agcgggaagc ggagaataca 396841 aagcgccgac gaccgacatg gaagagctgc ttgccggcat ctggcaggac gtgcttggaa 396901 tgtctgaagt cggtgtcacc gacaatttct tctcgcttgg cggagattcc atcaaaggaa 396961 ttcaaatggc gagccgcttg aatcagcacg gctggaagct ggaaatgaaa gatctcttcc 397021 agcatccgac gatcgaagag ctcacccagt acgtagagcg tgccgaaggc aaacaggcag 397081 accaaggccc ggtggagggc gaagtcatcc tgacgccgat ccagcgctgg ttctttgaaa 397141 agaacttcac gaacaagcac cactggaacc aatcggtgat gcttcacgcc aaaaagggct 397201 ttgatcctga acgggtggag aaaacattgc aggcgctgat cgagcatcat gacgcgctcc 397261 gcatggtcta ccgcgaggaa aacggggaca tcgttcaggt gtataaaccg atcggtgaga 397321 gcaaggtcag cttcgaaatc gtggatctgt acggctccga tgaagagatg ctgagaagcc 397381 agattaagct tctcgcgaac aagctgcaaa gcagtctcga tctgcgaaac gggccgcttt 397441 taaaggcgga gcaatatcgc acagaagctg gggatcacct gctcattgct gtacaccatc 397501 tcgtggtcga cggtgtgtca tggcggattt tgcttgaaga ctttgcttca ggctacatgc 397561 aggctgagaa agaagagagc cttgtcttcc cgcaaaaaac aaactccttc aaggattggg 397621 cggaagaact ggcggcattc agccaatcag cgcatctttt acagcaggct gaatactggt 397681 cgcaaattgc cgctgaacag gtttctcctt tacctaagga ttgtgaaaca gagcagcgga 397741 tcgtcaagga tacatcatct gtcctatgtg aattaacggc agaagacact aagcatcttt 397801 taacagatgt tcatcagcca tatggaactg aaatcaacga tattcttctc agcgcgctcg 397861 gtttgacaat gaaagaatgg acaaaggggg ccaaaattgg cattaacctt gagggacacg 397921 gccgggagga cattatcccg aatgtgaata tctccagaac ggtcggctgg tttacggcac 397981 aataccctgt tgtgctcgac atatctgacg cagatgcctc agctgtgatc aaaacagtca 398041 aagaaaacct gcgccgcatt ccggacaaag gtgttggcta cggcattctt cgttatttca 398101 cagaaacagc ggaaacaaag ggcttcacac cggagatcag cttcaactat ttgggccaat 398161 tcgacagtga agtcaaaacc gatttctttg aaccgtccgc tttcgatatg gggcgccaag 398221 taagcggaga atcagaggcg ctgtacgcat taagcttcag cggcatgatc agaaacggcc 398281 ggtttgtgct ttcctgctcc tacaatgaga aggagtttga aagagctaca gtcgaggagc 398341 aaatggaacg gtttaaagaa aacctcctga tgctaatccg ccattgcacg gaaaaagaag 398401 acaaggaatt cacaccaagc gacttcagcg ccgaagacct tgaaatggac gagatgggag 398461 atatctttga catgcttgag gagaatttaa aataaaacgc aagggaatta cagaaggcgg 398521 gagcgaaaca tatgagtcaa tttagcaagg atcaggttca agatatgtat tacctatcgc 398581 cgatgcagga agggatgctt tttcatgcca tcctgaatcc cggccaaagc ttttaccttg 398641 aacaaatcac gatgaaagta aaaggcagct tgaatatcaa atgtcttgaa gaaagcatga 398701 atgtgatcat ggaccggtac gatgtatttc gtaccgtgtt cattcacgaa aaagtaaaaa 398761 ggcctgtcca agtcgtattg aaaaaacggc agttccatat agaagaaatc gatctgacac 398821 acttaacggg cagcgagcaa acagccaaaa tcaatgagta caaagaacag gataagatca 398881 ggggttttga tttgacgcgg gatattccga tgcgggcagc cattttcaag aaagctgaag 398941 aaagctttga atgggtgtgg agctaccacc acattatttt ggacggatgg tgcttcggca 399001 tcgtcgtaca ggatctattt aaggtataca atgctctgcg cgaacaaaag ccgtacagcc 399061 tgccgcccgt caaaccgtat aaagactaca tcaagtggct tgaaaagcag gataaacaag 399121 catcactgcg ttactggcgc gaatatttag agggctttga aggacaaacg acgtttgcgg 399181 agcaaagaaa gaaacaaaag gacggctatg agccgaaaga gctgctcttt tcactgtcgg 399241 aggcggaaac aaaggccttt accgagcttg caaaatcgca gcataccact ttgagtacgg 399301 cgctgcaggc agtctggagc gtattgatca gccgctatca gcagtctggc gatttggcct 399361 tcggtacagt tgtttcaggg cgtcccgcgg aaatcaaagg cgttgaacat atggtcgggc 399421 tgtttatcaa cgttgtcccg agacgtgtga agctgtctga gggtatcaca tttaacggct 399481 tgctcaagcg gctgcaggag caatcgctgc agtccgagcc gcatcaatat gtgccgcttt 399541 atgacatcca aagccaggcc gatcagccga aactgattga ccacatcatt gtttttgaga 399601 actatccgct tcaggatgcg aaaaatgaag aaagcagtga aaacggcttt gatatggtgg 399661 atgttcatgt ttttgagaag tcgaattatg atctcaacct gatggcttcc ccgggagatg 399721 agatgctgat taagcttgcc tataatgaga atgtgtttga tgaggcgttt atcctgcgct 399781 tgaaatctca gcttcttaca gcaattcagc agctcatcca gaatcctgat cagcctgtca 399841 gcacgatcaa cctcgttgac gacagggaga gagaattttt gctaaccggc ttaaacccgc 399901 cggctcaagc tcatgaaaca aagcctctga cgtattggtt caaggaagca gtgaacgcca 399961 atccggatgc accggcgctt acgtattccg gccagaccct gtcttatcgc gaattagatg 400021 aggaagcgaa ccgcattgca cgccggctgc aaaaacacgg tgcgggcaaa ggctctgttg 400081 tagcgctgta cacgaagcgc tcacttgaac tggtgatcgg cattctcggt gtattaaagg 400141 cgggagcagc ctatctgccg gttgatccga agctgccaga ggaccgaatc tcgtatatgc 400201 tggctgacag tgcggcagcc tgtcttctga cgcatcagga gatgaaagaa caagcggctg 400261 agctgccgta tacaggcaca acgctcttca ttgatgatca aacacggttt gaagaacagg 400321 caagcgatcc tgcaaccgcg attgatccta atgatccggc atatatcatg tacacgtccg 400381 gcacaaccgg aaagccaaag ggcaatatca ccactcatgc caatattcaa ggattggtca 400441 agcatgtaga ctacatggca ttttctgatc aggatacgtt cttgtctgtt tcgaattacg 400501 cctttgatgc atttaccttt gatttctatg cttctatgct gaatgcggca cggctcatta 400561 tcgcagatga acatacgctg cttgatacag aacggctcac agatctgatc ctgcaagaga 400621 atgtcaatgt catgtttgcg acaaccgcac tatttaatct tctcacagat gcgggagagg 400681 attggatgaa ggggcttcgc tgtatattat tcggcggaga gcgcgcgtca gtgcctcatg 400741 tcagaaaagc gctgcggatc atggggccgg gcaagctgat taactgctac gggccgactg 400801 agggaacagt gtttgcgaca gctcacgtcg tgcatgatct gccggattcc atctcctcat 400861 tgccgatcgg aaagccgatc agcaatgcca gtgtttatat tctgaatgag caaagccagc 400921 tccagccatt cggggcggtc ggtgaactgt gcatcagcgg aatgggcgtg tcaaaagggt 400981 atgtaaatcg tgctgacctc acgaaggaaa agtttatcga gaacccgttc aagccgggag 401041 aaacgcttta ccgtacaggg gatttagcgc gctggctgcc ggatggaacg attgaatacg 401101 ccggccgtat tgacgaccag gtcaaaatac gcggacaccg gattgagctt gaagaaatcg 401161 aaaagcagct gcaggaatac ccaggtgtga aagatgcggt cgttgtggcg gaccgccatg 401221 agtctggcga tgcatcaatc aatgcctacc ttgtgaaccg aacgcagctt tcagctgaag 401281 acgtgaaggc gcacctgaaa aaacagcttc ctgcttacat ggtgccgcaa acctttacct 401341 tcttggatga gcttccttta acgacgaacg ggaaagtcaa taaacggctg ctcccaaaac 401401 ctgatcagga tcagctggcg gaagaatgga ttggaccgcg gaacgagatg gaagaaacaa 401461 tcgcacaaat atggtctgag gttctcggca gaaagcaaat tggcattcat gacgatttct 401521 ttgcgctcgg agggcattcc ttgaaggcca tgaccgccgc gtcccgcatc aagaaagagc 401581 tcgggattga tcttccagtg aagcttttgt ttgaagcgcc gacgatcgcc ggcatttcag 401641 cgtatttgaa aaacgggggc tctgatggct tgcaggatgt aacgataatg aatcaggatc 401701 aggagcagat cattttcgca tttccgccgg ttctgggcta tggccttatg taccaaaatc 401761 tgtccagccg cttgccgtca tacaagctat gcgcctttga ttttattgag gaggaagacc 401821 ggcttgaccg ctatgcggat ttgatccaga agctgcagcc ggaagggcct ttaacattgt 401881 ttggatattc agcgggatgc agcctggcgt ttgaagctgc gaaaaagctt gaggaacaag 401941 gccgtattgt tcagcggatc atcatggtgg attcctataa aaaacaaggt gtcagtgatc 402001 tggacggacg cacggttgaa agtgatgtcg aagcgttgat gaatgtcaat cgggacaatg 402061 aagcgctcaa cagcgaagcc gtcaaacacg gcctcaagca aaaaacacat gccttttact 402121 catactacgt caacctgatc agcacaggcc aggtgaaagc agatattgat ctgttgactt 402181 ccggcgctga ttttgacatg ccggaatggc ttgcatcatg ggaagaagct acaacaggtg 402241 tttaccgtgt gaaaagaggc ttcggaacac acgcagaaat gctgcagggc gaaacgctag 402301 ataggaatgc ggagattttg ctcgaatttc ttaatacaca aaccgtaacg gtttcataaa 402361 tgaagtgatg aaaggaggag acagccaatg agccaactct tcaaatcatt tgatgcgtcg 402421 gaaaaaacac agctcatctg ttttccgttt gccggcggct attcggcgtc gtttcgccct 402481 ctccatgctt ttttgcaggg ggagtgcgag atgctcgctg ccgagccgcc gggacacggc 402541 acgaatcaaa cgtcagccat tgaggatctc gaagagctga cggatttgta caagcaagaa 402601 ctgaaccttc gccctgatcg gccgtttgtg ctgttcggac acagtatggg cggaatgatc 402661 accttcaggc tggcgcaaaa gcttgagcgt gaaggcatct ttccgcaggc ggttatcatt 402721 tctgcaatcc agccgcctca tattcagcgg aagaaagtgt cccacctgcc tgatgatcag 402781 tttctcgatc atattatcca attaggcgga atgcccgcag agcttgttga aaataaggag 402841 gtcatgtcct ttttcctgcc ttctttccga tcagattacc gggctcttga acaatttgag 402901 ctttacgatc tggcccagat ccagtcgcct gttcatgtct ttaacgggct tgatgataaa 402961 aaatgcatac gagatgcgga agggtggaag aagtgggcaa aagacatcac attccatcaa 403021 tttgacggcg ggcacatgtt cctgctgtca caaacggaag aagtcgcaga acggattttt 403081 gcgatcttga atcagcatcc gatcattcaa ccgtgatcaa aagcggacag cttcggctgt 403141 tccgcttttt ttgtgttgaa tgccaatttc tgcatggtat aatagtcgaa atactcaaat 403201 aaaggcaggt cgaaacatgc gcacgtctcc caggatgaaa tggtttgtat tgctgtttac 403261 gtttgttttc gccatcggaa tgaactcatt cagaaattcc tttcaatttt ttatgctgcc 403321 aatggcagac gccttccatg ccgacaggtc gctgatttcg gtttctgtca gcatttttat 403381 gatcacaacc ggcatcgtcc agttttttgt cggttttttt atcgaccgtt tcagtgtcag 403441 aaaaattatg gcgctgggag ctgtttgcat cagcgcaagc tttttggtgc ttccttattc 403501 accgaatgtt catgtgtttt ccgccattta cggtgtgctt ggcggaatcg ggtattcctg 403561 cgcggtcggc gtgacgaccc agtatttcat cagctgttgg tttgacacac acaaaggtct 403621 ggcgcttgct attttgacca atgccaactc tgcgggcctg ctgcttctct cgcccatttg 403681 ggctgcggct ccgtatcatg ccggctggca gagcacctat accattttgg gaatcgtcat 403741 ggcggctgtt ctgctgccgc tcctcgtctt tgggatgaag cacccgccac atgcgcaagc 403801 ggaaactgtg aaaaaatctt atgattggcg agggttttgg aacgtgatga agcaatcccg 403861 cctcattcat atcctgtact tcggcgtgtt tacttgcgga tttacaatgg gaattattga 403921 tgctcacctc gtcccgatac tgaaggatgc gcatgtctct catgtcaacg gaatgatggc 403981 cgcgttcggg gcatttatca tcattggcgg attattggcg ggctggctgt cagatctcct 404041 cggcagcaga agcgtcatgc tatccatctt atttttcatt cggctgctca gcctcatttg 404101 cctgctcatt cccattctcg gaattcatca cagcgacctt tggtacttcg ggtttatcct 404161 gttattcggg ctcagttaca caggcgtgat cccgctgacc gcggcgtcaa tttcggaaag 404221 ctatcaaaca ggattgatcg gatcgctgtt aggcatcaat ttctttatcc atcaggttgc 404281 cggagctctc agcgtgtatg cgggcggttt gttttttgac atgactcatg gttatttact 404341 gattgtcgct gtgtgcatcg tgtttgtggg tttatcggct gtaatagagc tggtgccgtt 404401 tttagataaa cagaaggcaa aagaaaccca ccattcaata taaaaggatc agcactgtca 404461 atgctgatcc tttttaaatt tgagtttttt tgtttcggta tttttaagga taatctcctt 404521 gaatctgttc atctcctctt cggagtgaaa aaaatgtttg gggatcgcaa tatattggcc 404581 acttgatgta ttgaccctga agatattttt atattcgaaa acagctgtaa tttcatccca 404641 attgaaaatg aggtcatatt ttttagaaca tatacgaatt ccttcttggt tcagagtata 404701 tgttcttttg gatttcatcc gttcgttctt cttgtatgct ctggaaaact tcacatatag 404761 aagaaggagg agcagcagtg taaacagaac ggacatcacg ataatcaaca tactgttcat 404821 aaacaagtta agcgcgtcac ttccataaac gatacggggc catccgttaa tgaagttaac 404881 tgcagcaaat atggcgcaaa acaatagaaa gtaaaagcat gatatttttg cgatttgata 404941 aaaaaagatt tctcttacat ccttaaaagt gatttctcct ggaagattga tactttcact 405001 agcatattga atcatacggt aaacctacac ctctaaccat gtttttcctt ttagtctagc 405061 ataatttctc atttttttgc aggcatacca gggcgctttg tttttttctc cagattgata 405121 ttgctcccca ccacgccaat cataatacaa acagccccgg caagatgata ccaggccagg 405181 ctttcgttga gaatcacaaa tcctgcaatc atcgtcacaa tggtagatac atgattaaaa 405241 gcgctcattt taaacgcctc aattcgcgac agcgtatagt tagacagaaa tgaagtgaca 405301 agtgaagaca gcacgcccaa atacacaatg gcgagaacga agccgggctc ccggaacggc 405361 agaaaataag tgccgactgt tcccgccgct ccgtgacgca caagggcgat ggcgttgaag 405421 acgacaaagc cgatggctga catgatgtag gtgagctcgg tcagcttgaa ccgctgcgtc 405481 atttttctgg cagcagtatt gtacatcgct gaagacaaag cggacaatag gatcagcaaa 405541 gaccctttta agctggctga ttccacgtca acgcctttca tcacaaaaat aaacatgacg 405601 ccggcaacgg ataaaaccgt gaaccccttt tgcgtccacg ttgggcgttc ctttaaaaca 405661 taagcggcaa agaccatcgt gaaaatcgga atggctgcct gaataattcc cgcttcagag 405721 gaggacgagt acacaaggcc gaatgcctga aagctgaaaa ataacgcggg atacagcagg 405781 gcgagcggca aaatgtcaat gacgtccttt acgcggattg atagctttac ccagccgaat 405841 aagatcggta cagtggccgc agcaaacgca atggtgaacc gatgcgccaa aatatcaaac 405901 ggctctgctg tttgcagtgc gatttttacg aatagaaagg ataaaccgat aatgaacgaa 405961 tataaaatag ccgctatata agcgggggtt tgctgatgtt taaccataat gggaagggct 406021 cctttacctg aattgcagcg ccggtcgctc cctttattgt atggccgcgg tcagaacggt 406081 acaatgagaa aaacaatgaa ctgtaccggt acaaaacagg gggagaaggc atggagaaat 406141 atatgagtct attaacgagg atagaggaga tgatgcaaag cacctcatat caagaaggag 406201 acaggcttcc atctatccgt cagctgtccg cccgctacca agtcagcaaa agcacagtga 406261 tccgcgcgct gcaggagctg gaaaagcgcc accttatcta ttctgttccg aaaagcggct 406321 attatattgt gaaaaagtca gggaaatcaa aaagcgggca gcctggcccc atcgactttg 406381 ccacatctgc gccggatccc gatgtgtttc cgtatcttga ttttcagcac tgcatcaaca 406441 aagcgattga tacatacaaa aacgatttgt ttatttatgg gacgccaaag gggcttccat 406501 cactcatccg cgtactccga aagctcttgg ccactcaaca ggtatttgcg gatgaacggc 406561 atattttcat tacatcaggt gtccagcagg cgttatcctt gctttgtgcc atgccgttcc 406621 caaatgggaa agagaagatc gccattgaac agccgggcta ccatttgatg gtcgaacagc 406681 ttgagacact tgggattccc gccatcgggg tgaaacgaac ggaagaaggg cttgatatag 406741 ccaaggttga gcggttattt caaacagaat cgattaaatt tttttatacg atgccgcgct 406801 tccataaccc gcttgggtgc tcattgtcag agcgtgataa acaggagctt gtgagactgg 406861 cagaagcgta tgatgtctat ctcgttgagg atgattacct cggtgatctg gaggaaaata 406921 aaaaggcaga tccgctgtac gcatatgatc tgtcctcaca tgtcatctat ttgaaaagct 406981 tctcgaaaat gatgttcccc ggcctccgcg tgggggcggc tgttttgccc gaagcgctga 407041 ctgacacgtt ctatgcgtac aaaaagctga acgacatcga ctgttcgatg atttctcaag 407101 cggcattgga gatttacctg aaaagcggta tgtacggcag gcataaggag aaaatcagag 407161 attcttataa agagcggtcg ctgaggctac atcaagccat tcgaactcac aggcagctgg 407221 gaagcggacg ctttacgttc tccagcgggc aggcaccctg tatgcacacc catctggtgc 407281 ttcctcagga tctgcccgcc tcaagagtga ttcatagact ggaaaaacaa ggggttctcc 407341 ttgaggcgat agaccgtcat tatttatcag attatccgaa agaaaatcta ttaaaaatca 407401 atatttccaa tgtgaaaacg gaagatattg agcgcggtgt caagctgttg atgagccatt 407461 tataaaagct cttcgtacga gaccattgtg atatcctcgg ggaaatcagg gtgtacggcg 407521 catacagcca ttttgtagcc gggatcgacc tcatacgttt tgatatagca tggggaatgg 407581 ctgtccggaa gctcaatgga tacttgtccg tcctggtgca ggcgcactga aaaggaatca 407641 agcggaagcg ataagccttt gccttccttg tttgataaag ctttctttca ttgaccatag 407701 atgataaaaa tagtctgtct gctcgtcctt gtcttttgct aaaaggtcgc tgtactctgt 407761 ttttgaaaag aagcgcttgg cgatctcaag gctgatcggt ttcgtttttt cgatatctat 407821 gccgatcggc tgtgaatcaa acgcgcaaat gacccagcgt ccggagtgag aaatgttgaa 407881 atgagcgtcg ggaagatcag ggatgcacgg cttcccgtat tcctgcgtgc taaagcggat 407941 atcggatttg tccaactgat actgcctgct tatgactgag cgaacgagca catctcccag 408001 cagggtgcgg tgagcatctt ctttatgata aaatctccgg catttctccc gtttttcagg 408061 tgatatgaaa gacatgaacc gttcattttc ttcctgtgaa agcgggcggt ccatataaat 408121 tccgtaaatc ttcattctag atcctccgtc tgcaaaagat tgtcaaaacc atcctatcat 408181 acttccacaa gactcatata gaggagaaaa taaaaaaaca aagccaaggc ggctttgttt 408241 tagtgtacag gcggagatgc tttcactgcg gctgtccgcc ttgccacagc ataattcagc 408301 aactggattg actggggcaa tgaaaaacgc aaaataagtc cggtgaggat ggcggtcaaa 408361 atggtgccaa aaccgatcgg tccgcccatg ccccatgccg caaacaaaat ggttaattcc 408421 atgccgttcc gcacccattg cacattccag ccggtttttt ctgtaatcag catcatcagt 408481 gaatcacgcg gccccgcgcc aaggcctgct gatacataaa caccgacgcc gtaaccaatc 408541 agcaccacgc ctagagagaa gacgatgatc gagcctgtgt aggtcgagag ggcaggcaga 408601 atgaaattga aaaaatctat aaatacacca atgagcacca tattcaggag ggcaccaatt 408661 ttcggccaag ctctcgtaaa caatgacgtg aatccgacga tgagcgctcc aataatgatg 408721 gaccactggc cgacggtaag cccgaagtgc tgaaacaggc tgtaatgaaa tgcatcccac 408781 ggactaatgc cgagtgcttt tccttctatc gtcagggata caccaaaagc caaaatgatc 408841 aaaccggcaa aataaaatgt ccagcgcaga acaagttctt gcttcacgtg aggtcccttc 408901 tttcgtaaaa atcagtcgat tgtcattgta gcacatctga cagaagggcg gaataggcga 408961 aaggggctca acaaaaaaac agggccgccg gaggcgccct gtttcagcgt gttggcaaac 409021 ccttgcattc gttgtcaggc ctgtgcttcg gtgctcacga atttaacatt agctgtgctc 409081 caatgctcgc ccttcctaga cttcaaaggt tttcaatcac gctgaaaatc acaaaatcct 409141 aaaacgaata tcgttttagg attttgtcaa taatctgaaa cagggcgctg acgctctgtt 409201 tttcttatta cagcgggttc aaaatccggt ttaagaaccg ctgtgtccgt tcttcttttg 409261 gtgcggagaa aatttgctcc ggcggtccct gctccacgat aacgccgccg tcgatgaaga 409321 tgacttcatc cgcaacctcc tgcgcgaact tgatttcgtg ggtcacgacg accatggtcc 409381 agccttcatt ggccaagtcc ttgataacct tcagcacctc tccgacaagc tcgggatcaa 409441 gcgctgaggt cggttcgtca aacagcatga gctcaggctg tatcgccagt gcgcgggcga 409501 tgccgacgcg ctgctgctgg ccgccggaaa gctggaacgg atataaatcc attttgtcct 409561 tcaatccgac tttatcaaga agctgaatcg cttcttttct gacttcctct ttgttccgtt 409621 tttgcacctg aacagggccc tccatcacgt tttcgagggc tgtgcggtgc gggaacaggt 409681 gatacgcctg aaacaccatt ccggattttc ggcgaagctt taggatatcc gcctgtttca 409741 cctttttgga gaaatcgatg gagaaatcat caaatgcaag ctctccgcga ttcgggatct 409801 ccagagcgtt caggcagcgg agcagcgtcg ttttccctga acctgaaggc ccaagtatgg 409861 cgatgacttt tcctttttca atcttcatat ctatcttttt taaaatttca ttttcaccga 409921 atgatttgtt taatccttta acggtaagca tactcggaac ctccttattt ggccacgtag 409981 cggtcaagac gccgttcgat gacatgctgg acgagtgaga gcaggaagca gataatccaa 410041 taaataaagg ctgcttcaat atagatcact aaaatttgat caagattccg cgcgccgatt 410101 tcctgggctt ttctgaacag ctcagcgacc agaatttgag aggcgaggga tgtatcttta 410161 atcaggctga taaaggtatt ggataatggc gggatcgaca cacgaaacgc ctgcggcaaa 410221 atgacgcgga acagcgtttt ttgatgtgtc atgccaattg tgtagccggc ttcccattgc 410281 cctttcggca cggataaaat agatgcccga atgatttcag atgcataggc gccgacgttt 410341 aatgaaaagg cgataactgc gcttggaaat ggatctaatg tgacgttaaa ggccgggaac 410401 agatagaaaa tgatgaacaa ttgaacgaga agaggagtgc cgcgtattgc ggatacgtat 410461 acgctgaaca cccatctcaa aggtctcact ttcgacattc tggcaagcgc cgtaatcagc 410521 gccaggatca ttccgaatat aaaggaaaga atcgtaaggg gaatcgtata gtagattccc 410581 cctgaaagta tcggccagaa tgactgctgc accagatccc acgggatcgc cgtgccaagc 410641 gtcaatgccg gcagattatt tagaaacatc ttcgccgaac cattttttag aaattttaga 410701 aagagtcccg tcctctttca tttcttttaa tgctttgttg acttgatcaa caacctcgcc 410761 gcttccttta cggaacgtga aatatgttga ctgaggctca cctgtttcaa acgcgatttt 410821 cacgttttta ttgccagatg tttttaagta gttcaatacg gcaagcttat cgttgtatgt 410881 catatcgacg cggccttgct ggatcatttg aagggcctgc gccatgcctt caacgccttc 410941 tactttagcg ccggcatttg tagctaattt gttgtagttg cttgtcagtg attgagctga 411001 cgtttttcct tttacatctg cttcagactt aatatcgttg ttgtcttttt tcgttacgac 411061 aacggctctt gatgttgtgt atttatctga gaaatcatat ttgtcttcac gatctgtttt 411121 tccgacttgg ttggcaacaa cgtcaaaccg tttggaattc aggccggcaa acatactgtc 411181 ccattgtgtt tccttaaagt cgactttaag cccgaggcgt tttgcgactt ctgtgataac 411241 ttcgacatca tagccagtca gtttatcagt gtctttgtcg tggtaagtga acggctcata 411301 tgttccttcc gttccgactg tgagcacacc ttttttctta attgaagccc aaagatcgcc 411361 atctttggca ttatcttttg actgattgtc atttcctgct ccgcaagctg caagagctgc 411421 aatacttacg accatgaata aagccaataa tgcttttttc atcttattcc ccacttttct 411481 ggttgatttt attgaaataa aaaattagct tacaaatcta aaggataact tttttttagt 411541 atgagtcaag tatttggttt tcataagaca aaatctttta aaataaatcc aaaaattgct 411601 gtgccggttt aggcaaataa ctgtccgttc tccacatgac agccggtgtc ataatgaagg 411661 gattattttc gatatggacg gtgtgaacgt gatttctcat atgaacggga atcattgtga 411721 caggcaaaat agacgcgccg aatccggatg acacgaggct gagcaaagtt gcagagtcgt 411781 ggcattcaca aacaatgcgc ggctccaggt tcaaacgatg aaattcattc atgacctgat 411841 tatagacgcc ttttccgttg acaggccgca gcaggatcag cggaaatgaa ggaatgtcca 411901 ccatcttaat ggtgtctccg cacggatatc cggcttcatc tgaaagcacg agcacacatg 411961 gaatgtcatc aagctgcttg aattgtactg tgtcactttt gatcagtgtt gtcgtgaccg 412021 ccgcatcgat ttgccggctt tccagcagtt ccaacagtgt cgcgggttca ttttcccaaa 412081 tattaaaggt gagatggggg tatctctctt tgatctgtgt tactttttca agcatcagag 412141 ccgcgcaata aatcgttgat cccacggcaa gtgtaccggc tacttcctcc ttcagctcct 412201 gtacctcaat gactgcatct tcaaacctat gcagaatctc ttttgctctt tttagaaaaa 412261 cagctccttc atatgtaaga gtcatttgtt ttttcttgtt acggtcaaac agaacaacac 412321 caagttcgtc ctccagctgt ttgagctgcc tgcttaaagg cggctgcgcc atgtgaagct 412381 ttttggctgc ggacgtaatt ttctgttctt gggcaatggt aatgaagtat cgaagctggc 412441 gaatatccaa aagaaagcgc ctccttatca taccttttag gtattaatta tagatttaat 412501 agatattttt catatggata tatcaggagt atgattgaaa tgaaagcaga attcaagcgt 412561 aaaggagggg gcaaagtgaa actcgttgtc ggaatgacag gggcaacagg ggccattttc 412621 ggggtcaggc tgctgcagtg gctgaaggcc gccggagtgg aaacccatct cgttgtgtct 412681 ccttgggcaa acgtcacgat caaacacgaa acaggctata cgttacaaga agtagaacaa 412741 ctggccacat acacttactc acataaggat caggcggcag ccatttcaag cgggtcgttt 412801 gataccgatg gaatgattgt tgcgccgtgc agcatgaaat ctctcgcaag cattcgcaca 412861 ggaatggcgg ataatctgct gacacgtgcg gcggatgtca tgctcaagga gagaaaaaaa 412921 ctcgtcctct taacgagaga gacgcctttg aaccaaattc atctcgaaaa tatgctagcg 412981 cttacgaaaa tgggcaccat cattcttcct ccgatgccgg cattttataa tcggccgaga 413041 agcttagagg aaatggttga ccatattgtt tttagaacgt tggaccaatt cggcattcgg 413101 cttcctgaag cgaagcgctg gaatgggatt gaaaaacaaa aaggaggagc ttgatcatgg 413161 cttatcaaga tttcagagaa tttctcgctg cccttgaaaa agaaggacag ctgcttacag 413221 tgaatgaaga ggtaaagccg gaaccggatt taggggcctc cgcacgggca gccagcaatc 413281 ttggcgataa aagccctgcg ctcttattta acaacattta cggctatcat aacgcgcgaa 413341 ttgcgatgaa tgtcatcggc tcttggccaa accatgccat gatgctgggc atgccgaaag 413401 acacaccggt aaaagaacag ttttttgaat tcgcaaagcg ttatgaccag tttccgatgc 413461 cggtcaaacg tgaggaaaca gcgccatttc atgaaaatga aatcacagaa gatatcaatt 413521 tgttcgatat actgcctctt ttcagaatta accagggtga tggaggctac tatttagaca 413581 aagcatgtgt catttcccgt gatcttgagg accctgacaa cttcggcaaa caaaatgtcg 413641 gcatttacag aatgcaagtc aaaggaaaag accgccttgg cattcagcct gtcccgcagc 413701 acgatattgc aatccatctg cgccaagctg aagaacgcgg catcaacctt ccggtcacta 413761 ttgcgctcgg ctgtgagccg gtcattacaa cggcggcatc gactccgctt ctctatgatc 413821 aatcagaata cgaaatggca ggtgcgattc aaggcgaacc atatcgcatc gtcaaatcaa 413881 agctgtctga tcttgatgtt ccgtggggcg ctgaagtggt gcttgaaggt gagattattg 413941 ccggagagcg cgaatatgaa gggccgttcg gtgaattcac aggccattat tccggcggac 414001 gcagcatgcc gattatcaaa attaaacgcg tctatcacag aaacaatccg atctttgaac 414061 atttatactt aggcatgcct tggacagaat gcgattacat gatcggcatt aacacatgcg 414121 tgccgcttta tcagcagtta aaagaagcgt atccgaacga aattgtggca gtgaacgcca 414181 tgtacacaca cggtttaatc gcgattgttt ccacaaaaac ccgctatggc ggatttgcga 414241 aagcggtcgg catgcgcgca ctcacaacgc cgcacggact cggctactgc aaaatggtca 414301 tagtcgttga tgaggatgtc gatccattca accttccgca ggtcatgtgg gcgctttcga 414361 ccaaaatgca tccgaaacat gatgcggtca tcattccgga cttatctgtc ctgccgcttg 414421 atccgggatc caatccatca ggaatcactc acaaaatgat tctcgacgcc actacaccgg 414481 ttgcgccgga aacaagaggc cattattcac agccgcttga ttctccgcta acaacgaaag 414541 aatgggaaca aaaactaatg gacttaatga ataaataagg aaaggatgtt cgaaatgcat 414601 acatgtcctc gatgcgactc aaaaaaggga gaagtcatga gcaaatcgcc tgtagaaggc 414661 gcatgggaag tttatcagtg ccaaacatgc ttttttacat ggagatcctg tgaaccggaa 414721 agcattacaa atcccgaaaa atacaatcca gcgtttaaaa ttgatccaaa ggaaacagaa 414781 acagcaattg aagttccggc ggtgccggaa cgaaaggctt gatccgcgtg aactgtatgt 414841 cagaccgtct ctttgagctg cttgacggga gctgcctgaa tgagaagcag catgaggcct 414901 tcgttctgca aacagtatca gaggatggct ggccgcatgc cgctatgatc agtgcaggtg 414961 aaatcatcgc gctgagccga actgatatcc gaatcgctct gtggaaaaac acaatgactt 415021 cggccaacat ccttcgcaca ggaaaagcac agttcacggc gtggtggaag ggagcggcct 415081 attatgtaaa gcttgaatgc gcgcctttac cgcctttgaa agatgccgaa tatgaaagag 415141 accgtttttc ctgccgcatc gtttcagtga aagaggacgt tgcgaaatac gctgatttga 415201 cttcaggtgt ccgtatacag cttcacagcc ctgaagaggt gctgagcaga tggaaaaaga 415261 ccctggaaga tttaaaacgg taatatcgat agcctgacgc catgcgtcag gcttttttta 415321 tataatgaaa acaaaagggg gcgtgagaaa tggaacgtgc ggggatctgt cactcggacg 415381 gctttgattt agcttatcga attgagggcg agggcgcacc catccttgtg atcgggagtg 415441 cggtttacta tccgcgcctt ttttcctcag atatcaaaca gaaatatcaa tgggtctttg 415501 tcgaccatag gggatttgct aagcctaagc gggagcttcg tgcggaggat tcgaggcttg 415561 atgctgtctt ggctgatatc gaaaggatga gaacatttct tcagcttgag gatgttacta 415621 tcctgggaca ttccgggcac gcttttatgg ctttagagta tgccaggaca tatcccaaac 415681 aagttcggaa ggtggcgctc tttaatactg cgcctgataa cagtgaagaa agacagcgaa 415741 aaagcgaatc atttttcatg gaaacagcca gtcttgagag aaagaaacgc tttgaaaaag 415801 acatcgagaa tttgccgcag gacatcgaca aagatcctga aaggcgcttt gtgcacatgt 415861 gtattcgcgc tgaagcgaaa agcttttatc aagagcggcc gcatgctgct gccttatggg 415921 acggtgtatt cacgaatatg ccgatcattg atgaattatg gggcaataca tttgcccgga 415981 ttgatcttct tcagcggtta gctgatgttc gtatgccggt gtatatcgga ttagggagat 416041 atgattattt ggttgcgccc gtttcgctat gggatgctgt tgacggttta tatccccatg 416101 ttgataaggt tatttttgaa aagagcggcc atcagccgat gctggaagaa ccggaagcct 416161 ttgatcaaag cttcaggaaa tggcttgatc aataaaaaac agcccgcaga tcaacatccg 416221 cgggctgttt ctgattataa gacccctttc atcgcgcgtt tgatcaccgg cgagagcagc 416281 aggagaatgc cgccaagaac gatagaaatc aaaccgatgg tgccgaagta cattgtttca 416341 ggaattttat caaacaatcc ggctacttgg gcattgatcg cttgggctgc tgcgttcgtc 416401 agaaaccaca tactcattgt ctgtgcagag aaggcagctg gtgccagttt cgttgtcacg 416461 gataaaccga ctggagacag gcacagctct ccaagcacga caagcaggaa gctgagaacg 416521 agccaaagcg ggcttacgag tgcttctttt ccttgcatag cagggaatac cataatgata 416581 aatgacaatc cggctaaaat aattccgatt gagaatttaa ctggtgtaga cggctgacgt 416641 ttgccaagct tcatccagag ccatgcgaat attggcgcaa aaatgacaac aaacaatgga 416701 tttaatgatt ggaaccatga tgactgaagt tcgaatccgc ccaatgaaag tcttatgcgt 416761 tcatcagcgt ataccgcaag aatggtcgct ccctgttcct gaatggccca gaacatgaca 416821 gcaccgataa acaaaggaac gtaagcggca agacgggatt tttctgtttt gtccgctttt 416881 ttgcttgtaa acatgatgat gaaataaatc acaggaatca aaataccgag aatacttaca 416941 aggtcaatga aacgtttgat cgtcagcacg cctgtttgta cagagataat cactgcgatc 417001 gccacaatga taacaccgat tccggtgcca attgcagatt ttttagacag cggattcggc 417061 acattggaac ctgcaagccc gaggtttttc tttcttgtca aagcaaatac gataagtccg 417121 agaagcattc cgaccgcggc agctccgaat ccgagatgat agttgtactt ctgtccgagt 417181 gttccgacaa ttaacggcgc gagtaaacca ccgaggttaa tccccatgta gaaaatactg 417241 aaacctgagt cgcggcgcgg gtcttctttc gtgtaaagat ccccaactac gcttgaaacg 417301 tttggtttta ataagcctgt tccgacaatg ataagcacca tactgatata gaatgctatc 417361 gaactgcccg gataggcgag tgcaatgtgg ccgaacataa tgaatatgcc gccgtaaaac 417421 acggtgtttg cggtaccgaa tacccggtca gcgagccatc cgccaataat ggtggacatg 417481 tatacgagtg atccgtaaat cgacataatg gcaaccgcag tgcccttgtc aaagccgagc 417541 cctccgttta ccgtctctgt atacaaatag taaagtaaga ttgctctcat tccatagtaa 417601 gagaaacgct cccaaaattc ggtgaaaaat agtgtaaata gtcctcgcgg gtgaccaaag 417661 aacccttttt gcgggacgct tttaatgata ctttcgttat caatcgaagc catgtcagcc 417721 aaaccctttc taaaaaaagt gtattataaa aatcatattc ttatataata cttgtgtcaa 417781 tataatttat actcatttca aatagttcca tattggaaaa attataaata cctaaaaata 417841 gtgatttcct cctaattttt aaacttttta tcgtgagatt ttcttacaca actattcctt 417901 tatatttttt taataaaatt ttagagaaat gtacaagcag atcgggcctt tgtgagtaac 417961 atgatagtaa tcatagagaa ggaggctcgc aattggctga attcatatta aatgcagcgg 418021 atttcggtgt tcctagagat ggtaaaacgg attcgacaga acggattaat cagtgcctca 418081 gtacagctgt ttcgaaaggc tatcatactg tctggtttcc aaagggaaca tatttaatag 418141 acgcaacgct tggcggagat cttaatcaga ggtttcgaaa cgcggggatc attgttcccg 418201 gcaaccttga gattatgatg gaccccgaat gtatcatgaa agtgataccg aatagttcgt 418261 ggggttattc cgcattttat gtaggcaagc aagagaatat aactatttcc ggaggacaaa 418321 ttatcggcga acgggatgag catacgtatg cctcggcggg gataaggtca acccatgaat 418381 ggggctttgg catatgtatt gaaggatgct cgaatgttgt cattgatgat gtgaaaattt 418441 ccgattttac cggcgatggg atcatagtca gcccaagggg attaaagacc aatcaagatt 418501 atcgaacgtc agagcaaatt atcatccgcc gctgtgaggt tcggcggtcg aggagaaata 418561 acatttccat taccggatgt gacatggtca cggtggagga atgcttgatt gaagatgccg 418621 gaacggggaa tggaacagcg ccgaaattcg gaattgacat tgaaggatat ggcgaaggtg 418681 acgttgatta tgaggaaccg attaatgtat caattcgcaa taaccacttt gttggaaacg 418741 tttcaagttc tgtgaccaat tttaacgggt atggcatttt aatagaagga aatcactcag 418801 acaatacaat cagctacgga tatgggacgc aaacagtgat caagggcaat attctgagac 418861 gccctgaaga cgcggcggct gcgccaagag tcgggataac cggactcggt gtatcacaag 418921 gaaaagagac cagtgatgca gtgatcgctg gcaacctcat taccggattt tcaactggaa 418981 ttgatgtcag gggaaagagc gttcttgtga cgaacaacaa aatcagcaac tttgaaaaca 419041 cagggatatt ggtttatcag tcctccgacg taaaggtaga cggaaaccaa attcaaaacg 419101 gactgtctga aacaaggcgc agcatcggtc ttcgcgcagt gctgtcagat gacatcgcat 419161 ttctgaataa ctgtctcatt caagtcgttg acggtgtgaa cgtttccggc ggaaatatga 419221 tcattaaaga taatctcctg agaaaattca gccggggcat ttggattgct caagggaacg 419281 cggtgattga agggaataca ctgaatcctg acgcgtttga agcagtgccg gaatcatatt 419341 ctgtttccgt cacaaacaat gccggcgcca tcatcaaaaa caatacattt aaagagttca 419401 aaaattaccc catttattgc tccacaagtg caaaaacctc aattatcggc aaccacttag 419461 agcgatcccc gcttttggtc accatctata tcagcgcagg tgtgcatgag atttttgata 419521 ataccatttc agtcaacaga acagccggga atccgattgt gatttatctc aatggctctg 419581 caggctctat catctctgga aacaccatca ataacctctc cgcgggcact gcgacagcta 419641 ttcaaacaaa cacgtcaacc aattccaaaa tcatcggcaa ccgcattttt aaagggacca 419701 tcaacaaaca cagcagtgat acaatagacg gcaatatgat tgtctgaaaa aagcgccccc 419761 ctttaggggt tctttttttt cgatttatag atcacgtaca tttctctcac aagtactaac 419821 acaaaaaata aaagcacgac ccattccgca aatgttgtca tcttaaagct ggacatattg 419881 ttataaacgg cttttgttaa actgaaccct tgaagcatgt ccatcaacac agaaatagct 419941 aataaacaaa ttaatatgaa tccggtcacg cccaatatct tcatgcttca tcatcctccg 420001 cttttagtgt ctatctttgg cggagaagtt ataccgcatc taaccctaat gcataatctc 420061 aattttaaaa ggaagaatat gagaaaacga caaggaaagg tatttgtgta tgcctttatt 420121 ttctaagcga aagaacaata ccgattcaaa agacaagcag aatacagacg aaaggaatca 420181 ggaacagcag caagaaaaag aaaggccggt tctcatttct ccaagtttag caaagaatat 420241 agcggaaacg aaaaaggaag tcggaagcag ctctgacgtc atcattcgcg agattaaaat 420301 cggggagcag gatcatgtcc acctagctgt tatctatatt tctgggctgg tcgataataa 420361 cacgatccat gagtcgttaa ttgacccatt ggtacaggat gagtctatcc agaatactca 420421 tgcgatccag caaattcttg aaaaaacgct cccgctgggc ggggtgaaag cggaaaagag 420481 ctgggacaag cttttttccg agttaatgct tggcaatgcg ctcatttttg ctgatggcca 420541 tgatgaagct ttgatttgca gcactcaagg gggagagcag cgctccatcc aagagccgag 420601 cacccaggtg tcattccgcg gcccgcgcca agggtttaca gagtctctgc aaaccaatat 420661 ttccatgatc cggcgataca ttaaaaatcc gaatttatgg gttgaaaaaa tgaaaaaagg 420721 ttctgttacg aatacggata tcgctctcat gtacattcaa ggaatatgtg atgaaaaggt 420781 gctgaaggaa gtgaaacagc gcctggaaaa aatagatatt gacagtattt tggaatctgg 420841 atatattgag cagctgattg aagatgaaac ctttacgacg tttccgacta tgtatcatac 420901 agaacgccct gatgttgtag cgggtaatct gttagaagga agattcgcga ttattgtgga 420961 cggaacaccg tttgtgctta ttgccccagc cttatttgtc cagttttttc agtctgttga 421021 ggattattat tcgcgttttg acattgcgac aagcataaga attcttcgtg ttttagtctt 421081 tttcatttcg cttgtggcac cagctgtata cgtggcagcc acgacgtttc atcaagaaat 421141 gataccgact cagctgttag tggtcattgc ggcccagcgg gaaattgtcc cgtttccggc 421201 tgttgtggag gcgctgacga tggaggttgc ttttgagatt ctgagggaag cgggagtcag 421261 gctgccccgg gttgtcggct cggcagtgtc aatcgtaggc gcgctcgtaa tcggccaggc 421321 tgccgtacag gctggtatcg tctctccggc aatggtgatt atcgtggcac tcaccgcgat 421381 tgcgagcttc gcaacaccgg cgtttgcaat ggcgatttca gcccggctta ttcggtttat 421441 ctttattatt gcctcagctg ttatgggttt ttacgggctg attttaggga tcattatgat 421501 gtttgtccac ttatgcagtc ttcgttcatt cggcgttcca tatatgtcgc cgcttgcacc 421561 tttttcttca caaggcgtaa aggacgcgct tttccgggtt ccgtggtggg ccgatgaaaa 421621 aaggccggaa tcggtcagca aggaagataa ggtgcggcag gggaaagatc aacgcccaga 421681 gccggccgct tcacgaggaa tggtgaacaa agatttggaa gaaggggatc agaatggtac 421741 gtaaatgtct attagccgtt ctcatgcttt tgagcgtcat tgtgctgccc ggctgctggg 421801 ataagcggga gctgacggat cttgcgatta tctcggcgat tggcatcgat cggacaaacg 421861 acagcaacta cgtgctgcat cttcaaatta tcaatccagg aaatgttgcc ggcggccttc 421921 agggaggcgg tgctggagac aggccgcctg tatctgtcta ttcgattgaa ggtaacaata 421981 taacggaagc actcagaaaa gcctccatga aggtatcacg gcggctttat tttgcccata 422041 ccaatctagt cgtgatcaat gaaaagctgg caaaagaaga aggtttggat tttgtattag 422101 ataatcttga ccgggacaca gaattcagga caacagcaac attcgtcgtt gcccataaaa 422161 caaaagcaga aaatattgtg aaaatcttga cgccgattga taaaattccg tcaaataaag 422221 tcaataaaac actcgatttc acggaggcac aatacgggcg ggtggtcaaa atcaatattc 422281 aggacgtttt gaaaacactt gccgccaaca ctatggcacc ggtcatcccc ggatatatga 422341 tgattggtga cgataaaaaa ggagtcagca tggaaaacac gcaggcgact gacccgaaag 422401 ccattcttca ggcagatggt ttggcggttt ttgataaggc aggatattta aagtattggc 422461 tggaagatga tgaaagcgtg ggggcagtct ggcttatgaa taagatccag catacgttta 422521 ttaatgctga ctggggcaag acgaaggatg cggtcagctt gcaggttacc catcaagata 422581 caaagctggt accgaaaatg cggaacggac gcccgtacat ccatgtgaaa gtgtcggttg 422641 aaggtattat agatgctgtc aaataccctt tccaattgtc tgatcccaag gtgctggccg 422701 ctattgaaaa agcgctcaac aaagagcttg aaaaggaaat cagccatact gtgaaaaaga 422761 ttaagaagaa taaaatagat tttatcggtt ttggtgacac gatatataga aagtatccgg 422821 agcagtggga gaaaatgaag gacacttggg acaaagaata tttgccggaa ctgcccatcg 422881 atgtgaaggc cgagacgtat atcagaagga cgggattgcg aaacaatccg atcaaacacc 422941 agtttaaaga tgattaggtc tgaagaaagg ggaagtgaca gatggaaaaa gccagaataa 423001 gcataaggca gttgtttgtc atgattatca tttttgaact gggcagctcc ttattgatta 423061 caccgggatc aatggcgggc agggatgctt ggatagcagt tttattaggc tgtgcgatcg 423121 gactgtttct tttctatttg tatcaaggca tttatcaatg ttatccgaat tcttctccga 423181 aagaatatat ggatgatatg ctgggaacca agctgagctg gctgttttca tttctctata 423241 tcttgtactt tgcctatatt gccgcaaggg tgctgcgtga ctttggagaa atgctgctga 423301 cgtttgctta tcatgataca cctatcatta ttgtaaatgc tttattaatg gtagtaagca 423361 tatatgccgt aagaaaagga attgaagtac tcgcacgcgc ggccgaactt cttttcgggg 423421 ccatgtattt actgggcgcg atcggccttg tgctgattat tgtctcaggg actatagacc 423481 cgcacaattt aaagccggtt ttggcaaacg gcatttctcc tgtccttcac tctgttttca 423541 cacagaccat gtacgttcca tttggtgaag ttgttttatt tgtgatgatt ttccctaacc 423601 tgaatgacag aaaagatgtg aaaaaaatgg ggatgatcgc catggctatt agcggattga 423661 ttgtggcgct caccgtggcg attaatatta gcgtgcttga tgttgatctt acactcagat 423721 cccagtttcc gcttttaagc acgatccaga caatcaaggt cgaagaattt ttagaccggc 423781 tcgatgtctt ttttatgctg gcgctgatca tcggcggctt ctttaaggtc agcctctact 423841 tatatgccac tgtggttggg acatctacgc tctttaagga aaagaacccc tctcaattgg 423901 cttatccgat gggattgggc atcttaatcc tttctataac gatcgcgact aacttttcgg 423961 agcacttgaa tgaaggcctg aacgtggtgc cgctgtatat tcatttgcct tttcaattat 424021 tgtttccgct ctttctgttt attgtggccg tttggaaaaa gaaacgaaga gagaagtcaa 424081 aaggggagga agcaaaaaaa tgataaaaag agcgggggga tgcggccgcc gctcttttta 424141 tgttcacttc tatataaaag ggggatatag ggtgcgcccc tgtctgcact ggcagaggcg 424201 cgttttgtta tacgactgcg acgttttcct tcacagtaaa acttcctctt gaaagtctga 424261 tattgatgtc tgacactttt gcaatttgtt catcgtgcgt caccataatg acgcatttat 424321 cttccttgtg cgccagatcc tgaaagagcc gtacgatctc ttttgatgtg tcctcatcaa 424381 ggtttccggt cggttcatcg gctacgataa gatccgtgtc acagcagaaa gcccttgtaa 424441 ttgatacccg ctgctgctgt ccgccgctca gtgtgagcac tttttgccgg gcttgttttt 424501 cgttgatgcc aaccttctgc agcatgtcaa gcgcatatga ttctttgttc ttttctttag 424561 aacctgtgat ttccatagcg gttgtgacgt tctgcaaagc cgtcatatac gggagcaggt 424621 tgtacgcctg aaagacgatt gatacatatt gatttctgaa attggttaag ccgattttag 424681 aaaccgcttt tccgtcgtaa aggatgtttc cttcttttgg tgcgtcaagt ccgcctgcca 424741 gagacaggaa agtggttttc cccgtccctg atgttccgac gattgtgtag aattttcctt 424801 tttgaaagct gatgttaata tcctgaaaca atggctggct tttgttttta taccagtagc 424861 cgacttgttg aaattgtaat aagctcatag gttccgcctc tttctattcc tgttttgtca 424921 atatcgtttt cggatgaagc cgcagtactg aaattgacgg cagcaatgtt gcaatgattg 424981 cgattaggat gccgatcccg ccaagtataa gcatgtcgtt catagaaacc gcgacgttca 425041 gtgaatcgat aacgtccacg ttggatgaac tgtggccgaa cattttgccg cccatgccgc 425101 caccgccgcc gggcatttgt ccgcttgcgg tttgcgttga atcggttgat gaactgattt 425161 gctgggataa aagctgattt ccaagctgat tcgcgacgag atttcccgtc acagatgcaa 425221 ggccgatagc gataacggcc acaatcagaa tctcagtcaa gaactgtcca atcaatttcc 425281 atcgtttttc accgatggcc attaacacgc ccatttcgta tttgcgctcc ctgattgaca 425341 tcatgacaat caggccaaga atgacggcgc ctgccactga tacaagatac accacgtttt 425401 tagagaaaga agccacattt tcaatcggtc cgaccatttg ctggtaaagc tgatcgtttg 425461 tattcagtgt gtacgtatca aagtcaattg atgttttctt cgctgctttt acgaaagtat 425521 ccatattttt cgcgtcgtcc atatagtaaa cagctgagtc aatcgtattt ttatagtcgt 425581 cgcctttcaa tgccgctgtt gctgtgtaag gcgtataaag cttgttataa ggatttaaga 425641 aagagaaatt ttgggcttgg tcatcacctg aagatgttgt tttataaata ccgacgatct 425701 tcagttttac tgttgtatcc tcatccgttg ctgattcaat tgtgatcgaa tcgccaacgc 425761 ttaaatcatt ttcttccgct aatgtttcgt tgatcactgt tacttttttg ccgacatctg 425821 attttgtaat cgcgcgtccg tctgtgattt ttgaatctcc gtcagagaaa tcatcgacta 425881 acgctgtgct gatgacacct tcaatagaaa gatcagcttg aaccatttgc ggtccgcctt 425941 gtcctccgcc ttgactgttt ttagcgtttg agcttgaact gctggagctg gaatcacttg 426001 aactagagct ttcaatcgca tcaaagtttc ccgcgttggc tgaagctgat gtggtgtaat 426061 tgtagctctt cacatgatca agcgctgcaa gcttattcgc atcagacact ttgatcggtg 426121 tggattcgaa gctgcgcttt tcaccgctgt cctgctgttt ttccatttgc ttttggcggt 426181 caacctgaag tgtcacgctt ccaccgagtt cctgtctggc cagttcgctt gacttttgtg 426241 ctgccgactg gatggcgagg cctgatagaa caaagacaca tatgactgta aacacaaata 426301 attgcaataa cgtttttccc tttttagcct tcatattcca aaaggcccgt ttgataaagt 426361 tcatttatgt tcctccgtat aggtattttt attgataaga ccgcctctgg ggcgcgtccc 426421 cttgctgata aattaatagt agtccaaagg tatgaaaaaa atatgaacaa tctatttcta 426481 gttgatgaaa taaaaactaa caattgtgaa acgcaaaacc ttctgtttaa aatggtgcta 426541 ttatataaaa aagcatcaaa acaaccggag gatataatga aaatattaat gatagaagat 426601 aatgttagtg tatgtacgat gacggagatg ttctttttta aagaaggttt tgaagccgaa 426661 ttcgttcatg acgggttaga agggtaccag cgttttacgg aagaaaattg ggatctaatc 426721 attttggata tcatgcttcc atctatggac ggcgtgacca tctgcagaaa aataagagag 426781 acaagcacgg tgccgattat catgctgact gccaaagaca ctgaatcaga tcaggtcatc 426841 ggttttgaga tgggggcgga cgattatgtc acaaagccgt tcagcccgct gacattggtt 426901 gcccgcatca aagccgtcat cagaagatat aaggcgacag gcaaagcggt tattgatgaa 426961 gatatgattg aaacggaatg ctttaccatt aataagaaga cgagagaagt attattaaac 427021 ggagagcctg tagaaaatct cacgccgaag gaattcgatc tgctttatta ccttgtccaa 427081 aatccgcggc aggtgttctc cagagaacag ctgcttgagc aggtatgggg ctatcaattt 427141 tatggagatg agcgaacggt tgacgttcat atcaaacggc tgcggaaaaa gcttgccagc 427201 gaggacaagc ctttcctgta tactgtgtgg ggagtagggt ataaatttga tgaagattaa 427261 atatttatat cagctgctgc taagccatat cagcattttg attttagcgt ttgtcattat 427321 catttctctg ttttcccact ttgtgaagga atttgcctat cagaacaaag tagaggaatt 427381 gacgtcatat gcggtgcaga ttgcaaatga attccaatcc ggccaggtgg acatgcgcag 427441 gctctatcct tatcaggaca ttttaagcac aagaaagacg caatttatca tctttaatga 427501 agagcagcag ccttattttc ttcctgaagg ctttcatcac ccaccaaggg aacagctgaa 427561 gaaatcagaa tggaataagc tgaaaaaagg gcagactgtc acgatcaggg cagatggccg 427621 ttttgatgat gaagtgtccc ttgtggcgca gcctatattt gttcagaacg aatttaaagg 427681 cgccgttctg ctgatttctc cgatcagcgg tgttgaacag atggtcaatc aggtcaacct 427741 ctatatgttt tacgctgtga tcagcacgct tgtgattacg attcttgtga gctggcttct 427801 gtccaaattc catgtcaagc ggattcaaaa gctgagagaa gcgacagata aagtggcttc 427861 cggcgattat gacatccatt tggaaaacag ctacggggac gaaatcggcg tactggcgtc 427921 tgactttaat atcatggcga aaaaactaaa gcagtcaagg gatgaaatcg agcgccttga 427981 gaagcggaga aggcagttta tcgctgacgt gtcacatgaa ttaaaaacac cgctgacgac 428041 gatcaacggt ttggttgaag ggttgaacag ccatacgatt cctgaggata aaaaggataa 428101 atgcttctcg ctgatcagtg aggaaacgaa gcgcatgctg cggctcgtaa aagaaaatct 428161 ggattatgaa aaaatcagat cccagcaaat taccttgaac aagctagacg ttcctctgat 428221 cgaggtgttt gaaatcgtga aagagcactt gcagcagcag gcggaagaaa aacaaaacaa 428281 gctgatgatc caagtagagg atcacgtcat cgtacatgcc gattatgacc ggttcattca 428341 aattctcgtc aacattacga aaaacagcat ccaatttacg caaaacggtg acatttggct 428401 gcgcggaatg gaaggttata aagagacgat tattgaaatt gaagacacgg gtatcggcat 428461 tccaaaagag gatattgagc atatttggga gcgattctat aaagcagata tttcaagaac 428521 gaacacagca tacggtgaat acggactcgg tctctcgatc gtcaggcagc tcgttgaaat 428581 gcaccagggc acagtagaaa tcaagagtga agaagggaaa ggcacaaagt tcatcatccg 428641 ccttccttta acggcaaaac agcaatagca tacagggcgg cgcatcaact gatgcatccg 428701 ccttttttgc acaccgcttc ggtttattgc gtgctcccga aaacaaagat tgcgtgtttt 428761 tcgggttggg acggcctata aacatgataa aatatgacat aaacagtttt tgatgggaga 428821 gggtgaagga atgaagagtg gggtaattcc ttcttcagcg gtcggtcaaa aaattaacga 428881 gtggtacaga tatatccgga cattcagcgt gccggatgcc gaagtgttaa aagctgaaat 428941 ccagcaggaa ctgaaacaca tgcagcatga ttccaacttg ctgctttatt attcactaat 429001 ggaattccgg caccagctta tgctggatta tcttgagccg ttagagaaat taaatatcga 429061 agaccagcca agcctgtctg aattatcaag aaacattgac agcaaccagg cagatctcaa 429121 agggctgctc gactattacg tgaatttttt tcgcgggatg tatgaatttg ataagcggga 429181 atttatttct gccattacat actataaaca ggcggagaaa aagctctcct ttgtcgcaga 429241 ccatattgaa cgggctgaat tctattttaa aatcgcggaa gcttattatt atatgaagca 429301 aacgtatttt tcattgatta atataaaaaa cgcctatgaa atttacgtgg agcaggaaac 429361 ctataatgtg agaatcattc agtgccattt cgtcttcggg gtcaacctga tggatgaaag 429421 aaatttcgaa caagccgcac gccatttcaa attggcgctc aacatggccc aagcagaaca 429481 aaaagcccag ctggttggaa gagcatacta caatctcggg ttatgctatt acaatcaaga 429541 ccttctagac cctgccattg attactttga aaaagcggtc tccacatttg aaagcagcag 429601 gatcgtcaat tctctcccgc aagcctattt tttaatcacc ctgatttatt ataaacaggg 429661 aaaacatgat aaagcttcgg aatatcacaa gcggggctat gaatatgcta aagaaacaga 429721 cgatgcagac tatgccgtaa aattcgagtt tttgcaatcc ctatatctgg atcagcccaa 429781 tgaagaagga atcgaacgat gtttccagta cttaaaaaat aaaaatatgt acgctgatat 429841 agaggattta gccctagaag tagcaaaata ttactatgaa cagaaatggt ttaaactgtc 429901 tgcttcctac tttctacaag ttgaagaggc aagaaaacaa atacaaagga gtgaaggttt 429961 gtatgaaatt gaaatctaag ttgtttgtta tttgtttggc cgcagccgcg atttttacag 430021 cggctggcgt ttctgctaat gcggaagcac tcgactttca tgtgacagaa agaggaatga 430081 cgtaagaaca agccccttct cattagcgag aaggggtttt tcttttcaaa aaaacaccgc 430141 aagacatagt cttgcggtgc cgccttcatg gagattacgt ttatttagta gcctcctaca 430201 aatgcagttc ccacaatgat caagaggata aataacacaa caatcaaagc gaaagaagtt 430261 ccgtaacctg acattttgtg cacctccttg cgagattgct tcagcaaatg ctgcaaaact 430321 gtggcggaca gggtcccgca gagacggtca gcagcttaga agccgccaac aaacgcagtc 430381 cctacgataa ttaatagaat aaacaataca acgattaaag cgaaagaact gatgccgccg 430441 taaccgccgc cgttagagta tcctgacata aggtttcacc tccctatgaa ggatactata 430501 agatatgctg aaccgatcca tttggcaggg ataatagtgg acaagagaaa aaatgaagaa 430561 ttcggctata tgaaggtgat ataaaaaaat agcgggcgct gccgcccgct atttatgtac 430621 gattaagaga tcagcacgcc cgcgaaaaat tcctggtata acgcttgaac ggcttttctt 430681 tcttcggctt cttttacgcc aaacatcatg ctcacttcag aagacccctg attgatcatt 430741 tcgatattca cctgtgcctc tgataatgct ttggcggctc ttgccgttgt accgacattg 430801 tggcgcatcg cttcccctac aaccataatc agggcgagat gatgctcgac gatgacttca 430861 tcggcatgca aatcctcttc gatccgtttg atgacgctgc gttcagtggc ggcatccatt 430921 tgcccctgcc gtaaaatgat tgtcatgtca tcgattcccg atggaacatg ctcatacgtc 430981 aaaccatgct cctccaggat ttgaagggct ctgcggccaa aaccgatttc tctgttcatg 431041 agatacttgc tgatataaat gctgcaaaaa ccggtgtcgc tggcaatgcc gacgacaggc 431101 ccgtttgtgt tatcccgctt gctgacgacg cgggtgcctt cggctgaggg gttgttcgta 431161 tttttgatct gaacaggaat ccccgctctg aatgccggaa tgagcgcttc atcatgaaac 431221 actgaaaaac ccgcgtagga cagctcccgc atctctctat atgtcagctc gctgatttcc 431281 tttggattct caacgaagga cggattgaca gaatacacag cgtctacgtc tgtaaagttt 431341 tcgtacaaat cggcttgtag tccgttggca agaatcgaac cggtaatatc agaaccgctc 431401 cgtgagaatg tgatcacatc gccatccttg ctgaatccga aaaaaccggg aaaaatgatg 431461 agtccgtcac gttcccgaag acgatagagg ttttgatagg attcaggaag aacttgcgcg 431521 ttgccgggtt catttgtcac aaagaggccg gcatccttcg ggtttacata ttccgctttg 431581 acgcctttat aacggaagta agcggcgatc agtttggcat tgttatcctc tccgctggcc 431641 ttgactgcgt caaggtattg ttcgggattg cttttgtctc cttctaaaag cgtaaacaga 431701 tcatctctga ttttttcgat aatgctttgc cccagctgaa gctcattggc gatgagagcg 431761 taccgttcca caacagcttc cgccagttca ggtgcgctgc ctgttgccaa atattgttct 431821 gcacatgcga ttaagagatc agtcactttc gtatcctcgg catagtgttt tcccggagct 431881 gaaacgacta cagctttccg tgccggatct gaggtaacga tgtgaaacac cttgtcaagc 431941 tgggcgcctg aagcaagtga gctgcctccg aatttaacga ccttcatgtt tacatctcct 432001 aatgtttaaa attttcacac aaatttagta tttattatct ctctttcagt actgtaaatc 432061 aagggggaat ttctttctca ggagaacatt tgtatttttc acgaggaata atgttaggtt 432121 tgctgaccgt atgcctgcgt tataaagata aatatggtaa acagcctaac gttttgggat 432181 ggaaaatggt tagaatgatt agtaaaattg ataaatgact aggttaatat ttttaaagaa 432241 tattgactaa ccctataaaa atggtaatat gtaaatgata atgataatca attactatat 432301 ggccatattg ttttgagtcc ttgcggagta ggagatacgt tctttttgct gtaaggatgt 432361 aaggaggcag catgaagcta cgttacttat ttattctact tatcatatta gcagtcacat 432421 ctgtatttat cggtgtagaa gatctgtcgc cgcttgatct cttcgattta agcaaacaag 432481 aggcgtcaac gctgtttgca agccgtttgc cgcgattgat cagcattgtc attgcgggat 432541 taagcatgag catctgcggt ttgattatgc agcagatcag cagaaataaa ttcgtgtcac 432601 cgacgacggc gggcacgatg gattgggcga ggctcggcat tttaatttcc ttgctgctgt 432661 ttacatccgc cagtccttta atcaaaatgc tggtcgcgtt tgtctttgcc cttgcaggaa 432721 attttctgtt tatgaaaatc cttgaaagaa tcaagtttaa cgacaccatc tttattccgc 432781 ttgtcggttt aatgctcggg aatatcgtca gttcaatcgc gacatttatc gcatataaat 432841 atgacttgat ccagaatgtg tcatcatggc tgcagggaga cttctcttta gtcgtgaaag 432901 gaagatacga gcttctttat ctgagtattc cgctcgtcat cattgcctat gtgtatgcgg 432961 ataaattcac attggccggt atgggtgaaa gcttttctgt caacctcggc ctcaagtata 433021 aacgggttgt gaacatcggg ctcattatcg tgtccctgat cacgtctctt gtcattttga 433081 ctgtcggtat gctgccgttt ctcggtttaa tcatcccgaa tattgtatcg atttacagag 433141 gagacaatct gaagagcagc ctgccgcata ctgtgctgtt gggagcggtt tttgtgctgt 433201 tttgcgatat actgggcaga atcattatct tcccttatga aatctcgatt ggcctgatgg 433261 tcggaatcat cggcagcggc attttcctgt ttatgctgtt aaggagaaaa gcctatgcgt 433321 aaccagatga aaatagcttt gctcgttggt ttagccattg tatgtattgg cttgtttttg 433381 ttttatgact taggcaattg ggattacacc ctgccgagac gaatcaaaaa agtcgctgcc 433441 attgtgctga ctgggggagc gattgcgttt tcgaccatga tctttcaaac gattacgaac 433501 aaccgcatcc tgacgccgag cattttgggc cttgattctc tctacatgct gattcagact 433561 ggcattatct ttttgttcgg ttctgcgaat atggtcatca tgaataaaaa catcaacttt 433621 atcatctctg ttctgctgat gatcctgttt tctcttgttt tgtatcagat catgttcaag 433681 ggtgagggga gaaatatctt tttccttctg cttatcggaa tcgtgtttgg cacgctgttc 433741 agcagcctgt cttcttttat gcagatgctg attgatccga acgagttcca agttgtgcag 433801 gacaagatgt ttgccagctt taacaatatc aatacggatt tgttatggct cgcgttcatc 433861 atcttcctgc tgacaggcgt ttatgtctgg cgttttacaa aatttttcga tgtgctgtcg 433921 ctcggacgcg agcacgccgt gaatttgggc attgactacg acaaagtggt gaagcagatg 433981 ctgatcgtgg ttgcgatttt ggtttctgtt tcaacagcgc tagtcgggcc gattatgttt 434041 ttaggccttc tggtcgtcaa cctggcgaga gaattcctga aaacatataa gcattcatac 434101 ttaatcgcag gctccgtttt catcagcatc attgcgctgg tcggagggca gtttgtggtt 434161 gagaaagtgt ttaccttctc aacgacgctg agcgtcatta ttaattttgc cggcgggatt 434221 tattttatct acttgctgtt aaaggagaat aaatcatggt agaggtcaga aatgtaagca 434281 aacaatatgg cgggaaagtt gttcttgaag agacgtcagt cacgattcaa aagggcaaaa 434341 tcacctcgtt tatcggtcct aacggcgccg gcaaaagtac gctgctgtct atcatgagcc 434401 gcctgatcaa aaaggattcc ggcgagattt acatagacgg acaagagatt ggagcatgtg 434461 acagcaaaga gcttgccaag aaaatgagca ttttgaagca ggcgaaccaa atcaatatca 434521 ggctcacgat caaagacctc gtcagttttg gcaggtttcc gtactcacag ggccggctga 434581 cagaggaaga ctgggttcat atcaaccagg cgcttagcta tatgaagctg gaagacattc 434641 aagacaaata cttggatcag ctgagcggcg gacagtgcca aagggcattt atcgccatgg 434701 tcattgccca ggacacagat tatatctttc tggatgaacc gctgaacaat ctggatatga 434761 aacactcagt tgaaattatg aaactgctga aacggctggt agaggagctt ggaaaaacga 434821 tcgtgatcgt cattcacgat atcaattttg cttcagtcta ttctgactat atcgtcgctt 434881 tgaaaaacgg ccgaatcgtt aaagaaggac cgcctgaaga aatgatagaa acatcagtgc 434941 ttgaggaaat ctacgatatg accatcccga ttcagacgat tgataatcaa agaataggtg 435001 tttatttttc ttaatatata gaagaggtga ggagcatgaa aaagttcgcg ttactattca 435061 tcgctttggt cactgccgtt gtcatttctg catgcggaaa ccaaagcaca agcagcaaag 435121 gttctgatac aaagaaagaa caaatcacag tgaaacacca gctcgacaaa aacggcacaa 435181 aagtaccgaa gaaccctaaa aaagttgtcg tatttgactt tggaagctta gatacattag 435241 ataaactagg acttgatgat atagtagcgg gcctgccgaa acaagtcctt cctaaatatc 435301 tgtccaaatt caaggatgac aaatacgctg atgtcggcag cttaaaagag ccagacttcg 435361 acaaagtggc agaattagat cctgatctga tcattatttc agcaagacaa tctgagtctt 435421 acaaagaatt ctctaaaatt gcgccgacga tttaccttgg tgtagataca gcgaagtaca 435481 tggaatcatt taaatcagac gctgaaacaa tcggtaaaat ctttgataaa gaagacaaag 435541 tgaaagatga gctcgcaaac attgatcact caatcgcaga tgtaaagaaa accgctgaaa 435601 agcttaacaa aaacggtctc gtcatcatgg cgaacgatgg aaaaatcagc gcgttcggcc 435661 ctaaatcaag atacggcctg atccatgacg tattcggcgt ggctccggct gatcaaaaca 435721 tcaaagcgtc tacgcacgga caaagtgttt cttacgagta catttcaaaa acaaaccctg 435781 attacttgtt tgttattgac cgcggtacag caatcggaga aacatcatct acaaaacaag 435841 tcgtggaaaa cgattatgtg aaaaacgtaa acgcagtgaa aaatggtcat gtcatctacc 435901 ttgattctgc tacttggtat ttatcaggag gcggacttga gtctatgacg caaatgatta 435961 aagaagtgaa agacggttta gaaaagtaaa accaaaaaga gcctccgcta aatagcgggg 436021 ctcttttttt gttaatcagc gtgccggctg ctgttcggca gggcgctgag gtttctttaa 436081 tgtgaatgag agaaggaagc cgacaagtgc aatgacggca gccactataa aagcggcgtt 436141 catgccgtgc agggcggcgt gcttcacatt tgtcgtgcct gcatgtgccg cctggttgct 436201 catcacggaa accaatagtg cggttccgat cgagccgccg acttggcgaa tcgtgttgtt 436261 catcgcagtt ccgtgcggaa tcaagtggcg cggcagcgca ttgattccgg ctgttgtcac 436321 cggcatcatg atcatggcgg tgcctaagag acgaacggtg tataaaacga caatccaagc 436381 gagtgacgta tggtcagtca gctgcataaa cggcagagat gtcaggaaga tgatgcagaa 436441 accggcaatc gccagccctc ttccgccgac acggtcaaaa attctgccga taatcggcga 436501 cataaagccc atcacaacgg ctcccggcag gagcataagc cctgtatcaa aagctgtgac 436561 gtctctgaca ttttgtgtat aaagcggcag gatggtttcc gtaccgatca ataatgcaaa 436621 gacgagggtt cccagcagtg ttgttaagct gaaaacgcca aacgtgaaga cgcggaattc 436681 cagcatcggt tttttaagct tcatttgtct tgtgataaac aagagcagcg cgatgacacc 436741 caccagcagt gaaatcaaga cggttgaact ggaccagcca taagagccga cgcttgagaa 436801 gccgtacaga aggccgccga acccaaatgt tgaaaggatg actgataaaa tatcaatctg 436861 tgtttttctt aaagtcgtca cgtttttcat caggatgctg gcaagaatca aatcaatcac 436921 agcaaacgga agaataatat aaaacaatga tctccaagag aaagcttcga cagcccatcc 436981 ggaaagagtc ggtccgatcg caggcgcgaa tgagatgacc aatccgacca tacccatagc 437041 ctggccgcgc ttttcaatcg gaaagattgt caggaataca gtctgcatga gcggcatcat 437101 aatgccggct ccagccgctt gaatgatacg cgctgtcagc agaaccggga agttcggcgc 437161 gaacgctccg acgactgttc cggcagtgaa aatgctcatt gctgtgatga gcagcgcccg 437221 gcttgtgaat ttctcaatta aaaacgcggt aatcggaatt aaaatcccgt tggttaacat 437281 aaatgatgtt gtcagccatt gtgcttggtt ggcatcgaca ttgaaatccc tcatgatatg 437341 gggaagtgca gtaatcaaca atgtctggtt caaaatcgcc acaaacgctc cggctaacaa 437401 aatgccgaca atgacagaac ggttaaaagg tttttgttca atacttgtgt tcaatacata 437461 tcccttcttt tctctaagta attaacagtg tttttaacat ggaaacgggc tgtgttaaaa 437521 caccggtttg ttccagatag ccaatcagtg atttgagtaa aaaagcgcgg ggttcttcct 437581 tcttcgcttc ttcctccagc atagcggctg cggatgtcag ttcatctacg tcatagtccg 437641 cggcggacag ggaagagatg cctttatgta attccttcag gctttccgat aataggactg 437701 atttatcctt tggcttgtag gaggatgctg aatgaatata aagctcgatg gcttcgggcg 437761 gaagaagaga ctggcgggtt tccctgtttt tgataatctg attgagggtg ctgatgataa 437821 actctgcgat cgggtcaagc tcaagcggtt tttcctcgat tttgatcagc attaaaaact 437881 cacgcatcat gccgtgaaga atgataacca aatcccacac aaacgggaga atggtttctc 437941 catacgcctg gatcagcgaa tcgcggtgcc agcagataat cgtcgatctg gtctgatgga 438001 tatgctgttt gacccggtca ttgtgcagct tggggtttcc gtaggtcagc atattgaaaa 438061 actgctgatt ccgcctgaag ccctccagtt ccattttgac cttttgcgtc aaacgctcct 438121 ccggtgtaag tgctgtattt tcctgaagtc ttgaggccgc ggccaccatt tgcttctggt 438181 taaatgacag cagctccaaa agcagatctt ctttagattg gaacagctta tatatcgaag 438241 cttttgacat cttacattct tctgcgatcg cctgcatgga aaccgacgta aaatcctttt 438301 ccgaaaaaag ctttcgcgcg gctaacaaga tatctgtttt tttatcaagc atctcatggc 438361 ttccttcttt cttgaacatt agaaaaccca ttggttcaca gaaaaccaat gagtaacaat 438421 gaaaaaattt taccagataa acaaaataga agtcaatgga ttttaaccgg gtaaatgaaa 438481 ggcctgccgg aaaatccgac aggccgaata agagcttatt tttcaacttt aaatccttgt 438541 ttttcaagca tttcacggat gtgcggatag tacaggcgct catagtagga agcgatgctc 438601 tgtgaccagt ttcttgtttc ttttccgttt gtccgtttat tcatgtattc agacatctgt 438661 tcgtcgtatg cctgaatgtg agacgtcagc tcatcctgat tcaaataagt ttcctgatga 438721 ttgacagctt cctgcggcaa gcgcggtttt ttcgctgaac ggtcggcagg atgcccaatg 438781 acaaggccgg ataaagggaa cacgtatttc ggaagctcaa gcagttcgat cagctcttga 438841 gggtttccgc gaactgcacc gatcggaact gtgccaagtc cgagtgactc agccgctgct 438901 gttgctgtgc cgagggcaat accagcgtct actgcgccga caagaacaga ttccaatcca 438961 tttgtgattt ccattttgaa atcatgcaga tcttcaagcg caattttggc ccggttaaaa 439021 tctgcgcaga acagcaggaa aacaggagct tgatcgatcc atggctggcc gcctgccagc 439081 tcggagattt tctttttgcg ctctttatcc tggactgtga tcacagtcac ttgctgtccg 439141 ttgatagaag aaggggctga ttgcaccgct tcaatgattt ggtccaattg ctcctgagct 439201 acaggctcat ctgtgtagct gcgaatcgag cggtggtctg ttaaagattt aatcacttca 439261 ttcatatgag acacccttcc tttactcgct aagctctgtg cggacaacat caagaggagc 439321 gctcagcagt tcttttcctt ttgcgacaaa cccttggaaa tgcgcagttt cgttatggaa 439381 tttcattgcc gcttcatctt tccatttttc aagcatgaca aatgtatttt cttcgcctac 439441 tttttcgaat aggtcgtatt gcgcgttgcc ttcctcagct cttgaatgct gaacaagtga 439501 ttgagcctcg ctcaaaaatt cctcgcgttt ttctggtttt actttgatgt aagcttgtaa 439561 tacgatcatg taaatctcct ccgtcgttat gcgaatttat tgttcgaatt tcatcgaact 439621 aaatgtaaca tgtattctaa atgaggtaaa ggaaaaaccc ttatatagta aaattgtcat 439681 tctaattgtt gtatgataca tttgtgtcat gaacattcca aaccatccag aaacagaaac 439741 attgcagctg acaaaggttc ttcatgcact tagtgatccg cttcgtttag agctcgtcaa 439801 gcaattagct gaagcaaaag aaaaaacgtg cagcacctgt gcagatgtgc aggttgccaa 439861 atcgactttg tcgcatcatt ttaaagtttt gagagaatca ggcatcgctc aagttcggat 439921 agaaggaaag cgccggtatt attcgcttcg cgctgaagac cttgaaaagg catttccggg 439981 actgcttgaa gccgtgctga atgtagacca ggaccgctgg tgaatcaatc ccctgtaacg 440041 gggatttttt tatgtccgta aaccgctttg aaaagccgct gcacaccctc ctgaatatct 440101 tcttccttca gccgtgcaaa gccgataatg agagcaggcc tgcccgtttg ccgcttgttt 440161 tccttcaagt taaatcggct cattccgaat atttcaagct gcagcccggc agcatgtgac 440221 aggatgtctt gttcggtgcg cctggtatca aattcggtaa caaaatgcag ccccgcattt 440281 gcccctttta cggtaacctc tccgctgaac tctgcttcta aagcggtgat caggcgttct 440341 ctcttttctt tataatgctg cttcattttt tttatatgct tctgatattc accagactcg 440401 ataaattcct gcagggtgag ctgtgtgagt gatgagcaag tctgcagatc atagccccgc 440461 tgtttgtatg ccctcaacag ctcaggcggc aacaccatat agctgatccg taagccgggg 440521 agaagggact ttgaaaaggt tcccatatag atgacatttt gaaaacggtc gaggctttgc 440581 agcgccggaa tactgtctac atcatatgtg aattcactat cataatcgtc ctcaatgata 440641 tatcggcgcg gctcctcggc tgcccagttc agcagctgaa ttcttctgga tacaggcata 440701 atcgttccgg acggaaactg atgcgacggg gtggtcacca gcacatctgg ctgctgtctg 440761 gtgatttcag caatcgacat gcctttttca tccagcatga tcgtctttac ttgttttccg 440821 gcattcttca aaagctgata catgcgcctg tagccaggct cctccatcgc atacacggct 440881 tccttgggta aaagctcagt caacagctgc atgagcacct gtgtgcctgc ccctatgatc 440941 atttgttccg gcctgcattt tacacccctc gtcagggaaa tgagcctcgt aatggccgct 441001 ctcacttcat atatcccttg cggatgtgac atatcgccga gcgtgcggta tgagcgggag 441061 gccgcttttt gctcgcagcg gaaccagctt ttgatcggaa aatggtctgt atcggaactc 441121 atgtgtgaaa acgatatcca atcgctctgg tcgatgtgaa tctcttttag gtcatccggc 441181 agtgcaaatg gagggtgctc ctcggcggaa aacatgtcta gttcctccac gaagaaaccc 441241 tttcgttcaa tggcgtacaa atacccctca gccagcagct gctgataggc tgaattcact 441301 gaatttacgc tgaccttgag attttcagcc agctcccgct tggagggaac cttcgagtgc 441361 ggcagcagat tgcggctgag gatttctttt ttcagctttt gataaatttg ctgatagata 441421 taatcggctt gttctgaacg atcgagtgta atcgtgatat ccattttgta gtttctcctt 441481 ctgataccat caaaaagtta taattggtac ttttcatcat accaaagaga agtcagaatg 441541 ataagaaaat accgacaggg ggatattcac atgagtcaaa caacagcaag catcacaact 441601 gcacaatggc agcaaaaacg ggatcaattt gtgtcaaaag gtgtgagcaa cggcaaccgc 441661 agtctggcgg tcaaaggaga aggggccgag ctgtacgatc tggatggccg gagatttatt 441721 gattttgcag gcgccatcgg cacgttaaat gtcggacact cgcatccgaa ggtggttgag 441781 gctgtgaagc ggcaggcgga ggagctgatt catcctggtt ttaatgtcat gatgtacccg 441841 acttatatcg aattagcaga aaaactgtgc ggcatcgcgc cgggcagcca tgagaaaaaa 441901 gcgatttttc ttaactcagg ggcagaagcg gtcgaaaacg ctgtgaaaat cgccagaaag 441961 tatacaaagc gccaaggcgt tgtctcgttt acacgcgggt ttcacgggcg cacgaatatg 442021 acgatgagca tgacaagcaa ggtaaaacct tataaattcg gtttcgggcc ttttgcgcca 442081 gaggtttatc aagcgccgtt cccttattat tatcagaagc cggccggcat gagtgatgaa 442141 agctatgacg atatggtcat tcaagcattc aatgatttct ttatcgcttc agtggcgcct 442201 gaaacggtgg cgtgtgtcgt gatggagcca gtgcagggag aaggcggatt tattattcct 442261 tcgaaacggt tcgtacagca cgtcgcttca ttctgcaaag aacacggcat tgtttttgtt 442321 gctgatgaaa tccaaaccgg ctttgccaga actggcactt atttcgcaat tgagcacttt 442381 gatgtagtgc ccgatctgat cacggtttct aaatcgcttg cggcaggcct gccattaagc 442441 ggtgtgatcg ggcgtgcgga aatgcttgat gcggcagcgc caggggagct gggcggcacg 442501 tatgccggca gcccgctcgg ctgcgcggcg gctttggcag tcttggatat tatcgaagaa 442561 gaaggactga atgagcgatc tgaagaaatt ggcaaaatca ttgaagacaa ggcgtatgag 442621 tggaaacaag aattcccgtt catcggtgac atccgcagac tcggggcgat ggccgcaatc 442681 gaaatcgtca aggatcctga cacgcgtgag cctgataaga caaaagcagc agcgatcgcg 442741 gcctatgcga atcaaaacgg attacttttg ctgacagcgg gaattaacgg taatatcatc 442801 cgctttttga caccgctcgt catctcagac agcctattaa atgaagggct cagcatcttg 442861 gaggcgggcc tgcgagctta atcattggaa agaaaatggc cgggtctgct atcattttaa 442921 gtaatcatga aaagaaagga atgttcaata tgccagatca attaacggtc tacaacccgg 442981 ctacgggcga ggagatcaaa acgattcctc agcaatcagc cacagaggta gaagaagcca 443041 ttgaacgttc acatcaagcg tttaaaacgt ggtctaaaac atcagcgaac gaaagaacgt 443101 ctcttttgaa aaaatggtat gagctgattg ttgaacataa agaagagctt gcagatttaa 443161 ttacaaagga aaacggaaaa ccataccagg aagcagtcgg cgaggtactt tacggcgcag 443221 gctatatcga atggttcgca gaggaagcga agcgtgtgta cggaagaacg gtcccggccc 443281 cgacaactgg taaacgaatt gttgtcacac gccagccggt cggccccgtt gctgctatca 443341 cgccctggaa tttcccgaat gcgatgatta cacgcaaagc ggcgcctgct cttgccgccg 443401 gctgtacatt tatcatcaag ccggcgccgg acacaccgct gtctgcttat gaactagcgc 443461 gcctcgcata tgaagcgggc attccgaagg atgttcttca ggttgtgatc ggcgatggag 443521 aagaaatcgg aaatgtgttc acaagcagtc cgaaaatccg caaaatcacg ttcacaggct 443581 caacacctgt agggaaaatc cttatgaaaa acagcgctga caccgtaaag cacgtctcaa 443641 tggagctcgg cggacacgcc ccgctgatcg tagatgaaga tgcggacatt gaccttgccg 443701 ttgaacaggc gatggcgtcc aaataccgaa acgccggcca aacctgcgta tgtgccaacc 443761 gcctgatcgt tcatgaatcc attaaagatg aatttgctgc gaaactgagc gagcaagtgt 443821 ctaagctgaa agtcggaaat ggacttgagg aaggcgtcaa tgtcggcccg attatcaaca 443881 aacgaggctt cgaaaaaatc gtcagccaaa tagatgatgc ggttgaaaaa ggcgcgaaag 443941 tgattgctgg gggcacatat gaccgaaacg atgacaaagg gtgctacttt gtgaatccga 444001 cagtgctcac cgatgtcgat acgtccatga acatcatgca tgaggaaaca ttcggcccgg 444061 tcgccccgat cgtcacgttt tctgatattg atgaagcgat tcagcttgcc aacgatacac 444121 cgtatggctt ggctgcttac ttcttcacag aaaactaccg ccgcggcatc tatatttccg 444181 agaatctaga gtatggcatt atcggctgga atgacggcgg accgtcagcg gttcaagcgc 444241 cattcggcgg aatgaaagaa agcggcatcg gccgtgaagg cggttcagaa ggtatcgagc 444301 cgtaccttga aacaaaatat ttgtccatcg gtttataaaa gaatgcacgc tcctgagagc 444361 tgccggattt tccggcagct ctttttgtgt tccggcgaat aatcacaaca attccagcca 444421 aaataacagc aaatacattt tgaaagaagg ttccccaaca atggatttat tattggctct 444481 tctcccggct ttgttttggg ggagcattgt tctcttcaat gtgaaattag gcggcgggcc 444541 gtacagccag acactgggaa cgacgatcgg ggcactcatt gtttctatcg ttatttactt 444601 ttttgttcag cccgttctgt cccttcgcat ttttattgtt ggaatcgtat ccggcttatt 444661 ttggtcactt ggacaggcca accagttgaa aagcattcaa ttgatgggcg tgtcgaaaac 444721 aatgccgatt tccacaggaa tgcagctcgt ttccacctcg ctgttcggtg tgatcgtgtt 444781 ccgcgaatgg tcaacaccga ttgcgattac gcttggcgtt ctcgctttga tctttatcat 444841 tgtgggaatc attctcacgt ccttggaaga taagaatgat aaaaaagagg gcgagccaag 444901 caatttgaaa aagggcattt tgattctcct tgtttcgact cttggttatt tggtttatgt 444961 agtcgtggct agattattca atgtgtccgg ctggtccgcg ctgctgccac aggcaattgg 445021 catggtggtc ggggggttag ttttaaccta tagacacaaa ccctttaaca agtatgcgat 445081 cagaaatatt ctcccagggt taatctgggc aggcggaaat atgtttttgt ttatttctca 445141 gccgcgagtc ggcgttgcaa cgagcttttc cctttcacaa atgggaattg tcatttctac 445201 gctcggcggt attttcatcc tgcgtgaaaa gaaaacgaaa cgccagctaa tagcaattgc 445261 gatcgggatt atcctgatta ttgccgccgc cgtattctta ggaatcgcca aaacaaattc 445321 ataacaaatg gaggaggatg tatatgtatc cggatttaaa aggaaaagtc gtcgctatta 445381 caggagctgc ttcagggctc ggaaaggcga tggccattcg cttcggcaag gagcaggcaa 445441 aagtggttat caactattat agtaataaac aagatccgaa cgaggtaaaa gaagaggtca 445501 tcaaggcggg cggtgaagct gttgtcgtcc aaggagatgt cacgaaagag gaagatgtaa 445561 aaaatatcgt gcaaacggca attaaggagt tcggcacact cgatattatg attaataatg 445621 ccggtcttga aaatcctgtg ccatctcacg aaatgccgct caaggattgg gataaagtca 445681 tcggcacgaa cttaacgggt gcctttttag gaagccgtga agcgattaaa tatttcgtag 445741 aaaacgatat caagggaaat gtcattaaca tgtccagtgt gcacgaagtg attccttggc 445801 cgttatttgt ccactatgcg gcaagtaaag gcgggataaa gctgatgaca gaaacattag 445861 cgttggaata cgcgccgaag ggcattcgcg tcaataatat tgggccaggt gcgatcaaca 445921 cgccaatcaa tgctgaaaaa ttcgctgacc ctaaacagaa agctgatgta gaaagcatga 445981 ttccaatggg atatatcggc gaaccggagg agatcgccgc agtagcagcc tggcttgctt 446041 cgaaggaagc cagctacgtc acaggcatca cgttattcgc ggacggcggt atgacacaat 446101 atccttcatt ccaggcaggc cgcggttaaa cataaaaagc gacccagaca tgacatctgg 446161 atcgctttct ttattaggca cgctttttct ttacaagtgc tgctacagat aaaataatgg 446221 cagccgcaga cagcaccatc gctgtaatgt ctagagctga agaacctgag ttttcggaat 446281 cgtcttctgt tttcgtggcg ccgtgctcat ctgtcacttg ctttgcagac gtgatgtttg 446341 taatggaatg aggtgtatcg gcatcctcgt cacctgtcca ctcaacaatg ctgccgtctt 446401 tgtaatattg gtatgcgtcc caagcagctt cctccgcttt gtcagggttt ttggcaacaa 446461 aggtaaactg ctggaactgg ccttcctgaa tgcctccgtc agtcgcctcc catgtcacgg 446521 atactgattt gtcatcatgt ttttgagtgg aaaccttcca gcccggaatt ggctcatatt 446581 gctggaattc aacatccttc ggcattttga ggacaacctt cgttgtcggc agatttttct 446641 cagaaggaac cttcattgta tacgtttccc aagagcctgc agcagactca gccggtttta 446701 cagaaacatg cgcgctggca ggggccgtaa agaataagag ggagccgaca atagccggac 446761 atagtgtcaa tgcgattttt ttcaacaacg taaacactcc ttaattggtc tttgtaaaca 446821 tgatattgat ttcgttaaag tcgccggtca ggccgtggac tttgatcttc cagtttcctt 446881 tttcattaat cgacaggttt tgatcttgga agacgccttt tgttttttct tttaatgtaa 446941 aggtgctttt gttttcgctg cctgacaggc ctgttttata aacggttaac gtgatttgct 447001 ggatgttttt cacgggatca ccgttatggt cggtgacccg cagctcaaaa acattttttc 447061 caggctggtt tgggctgatg ctgagagaaa cgctttgtcc gttctctatc gctttggttt 447121 ggtagaacgg ttccggcgct ggctcaggcg ggcttggcag gcttgtaaac acggccgctg 447181 tgatcaatac agcgatgccg attgcccact ccgctttcaa cgttcggctg attcctgtgc 447241 ggcgctgctt tctggtaagc agaaaatgaa ttgcgcctaa gaccagcatg aaaacaaaca 447301 gcccgctttt cactaaaaga gcttgtccgt acgctgtatg gaacagtgaa tccattgaac 447361 gaatgatgaa aaatccattg agcaagcctg aaaacaaaat gacgccgact gcagtgagcg 447421 cccatgggga gaaccgtctg accgtctccc acgcgagcgt tttgtcaggc tgcctccatt 447481 cttttgagag cagcaaaacg agtgccgcta ttccgccgac ccagatggaa gcggaagtta 447541 aatgaaggaa atccatcaaa atgccgaccg ttttttcttc aacgacagca gcatgcccgg 447601 taaacgcctt ggcaagcagg agaccgaaaa agaaaatgag cggcgctgtc caatagccaa 447661 aggatgaaaa gcggtttttc cgtatcgcag ggatgacaga cagtgcgagc agcacgaaca 447721 gcgcagcctg tatgatccaa atggagccgc ctgctgtctc aaacagtgtt tctctgatgt 447781 agcccggctg gaatgcgctg ccccagccgc cgcctgcgtt cgcttttgtc tgaatcggaa 447841 gctgaagcaa aagcgccagc cccaatgctg cgatcgagcc ggtcaggata cgtctcgtcc 447901 gtttgacgag ctgttctgat ttccctttat accagaaaag atggaagaaa accgttccga 447961 taaacagaga taaggctgta tacagaatcg cgcgatctgc tgctgttccc ggattcagcg 448021 ctgaatcggc tgctttttgg ctgctgaatc cgccatccgc tttcccgata ctgaacggaa 448081 tgacgccgga aacaggatgt ccatccgcgg atacggcatt ccattccgct ctgtacacat 448141 ctttaggcag attcttcttc agcttcactg tcatgatgtg atgattatct tttttgattt 448201 cagtcttgtc cgtatccaca cggtcgccgt ttgaattata gactttaatg taatgaaacc 448261 cttcttcaac cggttcatta aattcgattt ccacctgcgc aggggcgctt tttaattcgc 448321 tgttttcccc aggtgaagat ttgacaatat aggcgtgagc aaagcttgtt ttcggcagga 448381 aaacaagaaa aagcagaagg atgatccacc atctgtttcg cttcatcact cagacaccac 448441 cttccgctgt atgtgttgtg ttatttcttg gtgcaggtgc agcgtttctt tcggtcttga 448501 agcatgtctt ccagcgcttg gtcgaaagtg cagacggctc cgccgaatcc tttttgaaat 448561 cgttcggcat ggtcaagtgt cgcaaacgga atggcctgcg gctggcagca gtgcaggttt 448621 aattcagcat ttacgacgaa ataagccgaa ccggcactga cggttgtctg taacagaaaa 448681 tctctgcaaa tcaagtgtga aacctcttcc gttttatccg cgtaacgcaa aaacgcgcaa 448741 tgtgcgcagc atagctgttc aatgtcttgg tttaccgtaa tcagctgaac cgaatgagct 448801 tgattgacgg gcttcaagca atagctgcac atatgatctg tttgaggtgt tcggacgggg 448861 agcgtgatgc cgccggccgt tttaatgacc tgatttgact gaaccagctg attgacatct 448921 ctatataccg tcatttccga aacgccgaac cttgcgctga tgtcagaaat tctaagcgag 448981 ccttcttctt tcagccactt cagtatgtgt tgctgtctat taatcggaag cattcataca 449041 ccctcttcat taagatctat ttaagcgtag aggattttag agacggagac aagtaagtgg 449101 atgataaaaa atgtgaaaat gtgttgaaca gcaacaaaac gaaacagaag ggactctggt 449161 ataatagaca gatggaatag aaagtgagga ataccctatg aaagaaacac catgcccgaa 449221 ctgcggcaaa cctttgacag gcgatatggt cagatcatca aatgtgcctt gtcaatttcg 449281 ctgcggccac tgccgggaac ggctttatga atataaagtt tcagctccga ttatgctggt 449341 atcattagcg gccatcgtgc tgcttattta tcttttgatg ctcctccgca atgcggcagg 449401 ctcagtgctg ccagctgtac agcacgtgcc gatggctgta tttgcgcttg tgtgcgcgta 449461 tcccgttttt attgtgagtg agcggatgat tgcaaagtac gtgattcaaa atggcaacat 449521 catttataga ggaaagagaa aaggctcctg aaaccaggag cctttttatt tttaaaaaat 449581 tgtcacagtc atgtgccaaa gtcctcttta ctttcaattg tatagggact gtaagcgttt 449641 taacatagag tcaaagggaa gcatcattct ctgaacatat ttttgtatct tacagcgaca 449701 aacaaaacag ggagggttta tatatgcagc agcaagaaca gcagcaaggc ggcatgaaag 449761 tgaaagtgca acgctttggg agttatttga gcggaatgat catgccgaat atcggcgcgt 449821 ttatcgcgtg gggtatcatt accgcgctgt ttattccggc aggatggttt ccgaatgaac 449881 agctgaacac gctggtcagc ccgatgatta cgtatttatt gccgcttttg atagcgtata 449941 caggcggaaa aatgatctac gaccaccgcg gcggagttgt cggagcgaca gcggcaattg 450001 gggtgattgt aggatcggat attccaatgt ttttaggcgc aatgattatg ggtccgcttg 450061 gcggatacct cattaaacag actgataaat tattcaagga taaagtcaag caaggctttg 450121 aaatgctgat caacaacttt acggcaggga ttgtcggcgc ggctttaacg attctcgcgt 450181 tttacgccat cggcccggtt gtcttgacgc taaataaatt gctggcggct ggtgtggaag 450241 tcattgtaca cgctaattta ctgccggtag ccagtgtttt tgtagaaccg gcgaaagtgt 450301 tgttccttaa caacgccata aaccatggaa tcttaagccc gatcggaatc gagcaagcat 450361 ctcaaacagg aaaatcaatt ctgtttttag tagaagcaaa ccctggaccg gggctcggca 450421 ttttgctggc ctacatgttc tttggcaaag gatcttcaaa atcaacggct cccggtgcgg 450481 cgatcatcca tttcttcgga gggattcacg agatttactt cccgtacatt ctgatgaaac 450541 cggccctgat tctcgcagcc attgccggcg gagcaagcgg actcttaaca tttacgatct 450601 ttaatgccgg acttgtcgcg gcagcgtcac cgggaagcat tatcgcattg atggcaatga 450661 cgccaagagg aggctatttc ggcgtattgg cgggtgtatt ggtcgctgca gctgtatcgt 450721 tcatcgtttc agcagtgatc ctgaaatcct ctaaagctag tgaagaagac ctggctgccg 450781 caacagaaaa aatgcagtcc atgaagggga agaaaagcca agcagcagct gctttagagg 450841 cggaacaagc caaagcagaa gaagcgtctg agctgtctcc tgaaagcgtg aacaaaatta 450901 tctttgcgtg tgatgcggga atgggatcaa gtgccatggg ggcatccatc ttaagaaaca 450961 aagtgaaaaa agcggagctt gacatcagtg tgaccaacac ggccattaac aatctgccaa 451021 gcgatgcgga tattgtcatc acccacaaag atttaacaga ccgcgcgaaa gcaaagctgc 451081 cgaacgcgac gcacatatca gtggataact tcttaaacag cccgaaatac gacgagctga 451141 ttgaaaagct gaaaaagtaa tcttatagaa agagagtgat tgtcatgcaa gtactcgcaa 451201 aggaaaacat taaactcaat caaacggtat catcaaaaga agaggctatc aaattggcag 451261 gccagacgct gattgacaac ggctacgtga cagaggatta cattagcaaa atgtttgaac 451321 gtgaagaaac gtcttctacg tttatgggga atttcattgc cattccacac ggcacagaag 451381 aagcgaaaag cgaggtgctt cactcaggaa tttcaatcat acagattcca gagggcgttg 451441 agtacggaga aggcaacacg gcaaaagtgg tattcggcat tgcgggtaaa aataatgagc 451501 atttagacat tttgtctaac atcgccatta tctgttcaga agaagaaaac attgaacgcc 451561 tgatctccgc taaaagcgaa gaagatttga tcgccatttt caacgaggtg aactgacatg 451621 atcgccttac atttcggtgc gggaaatatc gggagaggat ttatcggcgc gctgcttcac 451681 cactccggct atgatgtggt gtttgcggat gtgaacgaaa cgatggtcag cctcctcaat 451741 gaaaaaaaag aatacacagt ggaactggcg gaagagggac gttcatcgga gatcattggc 451801 ccggtgagcg ctattaacag cggcagtcag accgaggagc tgtaccggct gatgaatgag 451861 gcggcgctca tcacaacagc tgtcggcccg aatgtgctga agctgattgc cccgtctatc 451921 gcagaaggtt taagacgaag aaatactgca aacacactga atatcattgc ctgcgaaaat 451981 atgattggcg gaagcagctt cttaaagaaa gaaatataca gccatttaac ggaagcagag 452041 cagaaatccg tcagtgaaac ggtaggtttt ccgaattctg ccgttgaccg gatcgtcccg 452101 attcagcatc atgaagaccc gctgaaagta tcggttgaac catttttcga atgggtcatt 452161 gatgaatcag gctttaaagg gaaaacacca gtcataaacg gcgcactgtt tgttgatgat 452221 ttaacgccgt acatcgaacg gaagctgttt acggtcaata ccggacacgc ggtcacagcg 452281 tatgtcggct atcagcgcgg actcaaaacg gtcaaagaag caattgatca tccggaaatc 452341 cgccgtgttg ttcattcggc gctgcttgaa actggtgact atctcgtcaa atcgtatggc 452401 tttaagcaaa ctgaacacga acaatatatc aaaaaaatca tcggtcgctt tgaaaatcct 452461 ttcatttcgg acgatgtgac ccgcgtagcg aggtcacctc tcagaaaact gggagaaaat 452521 gatagacttg taggcccggc aaagaaaata aaagaaccga atgcactggc tgaaggaatt 452581 gccgcagcac tgcgcttcga tttcaccggt gaccctgaag cggttgaact gcaagcgctg 452641 atcgaagaaa aaggatacag cggcgtactt caagaggtgt gcggcattca gtcccatgaa 452701 ccgttgcacg ccatcatttt aaagaaactt aatcaataac cgaccacccg tgacacaatg 452761 tcacgggctt tttttactat ctcgcaatct agtataatag aaagcgctta cgataacagg 452821 ggaaggagaa tgacgatgaa acaatttgag attgcggcaa taccgggaga cggagtagga 452881 aaagaggttg tagcggctgc tgagaaagtg cttcatacag cggctgaggt acacggaggt 452941 ttgtcattct cattcacagc ttttccatgg agctgtgatt attacttgga gcacggcaaa 453001 atgatgcccg aagatggaat acatacgctt actcaatttg aagcagtttt tttgggagct 453061 gtcggaaatc cgaagctggt tcccgatcat atatcgttat gggggctgct gctgaaaatc 453121 cggagggagc ttgagctttc cattaatatg agacccgcca aacaaatggc aggcattacg 453181 tcgccgcttc tgcatccaaa tgattttgac ttcgtggtga ttcgcgagaa cagtgaaggt 453241 gaatacagtg aagttggcgg gcgcattcac agaggcgatg atgaaatcgc catccagaat 453301 gccgtgttta cgagaaaagc gacagaacgt gtcatgcgct ttgccttcga attggcgaaa 453361 aaacggcgca gccatgtgac aagcgccaca aagtctaacg gcatttatca cgcgatgccg 453421 ttttgggatg aagtctttca gcagacagcc gctgattata gcggaatcga aacatcatct 453481 cagcatattg atgcgctggc cgcttttttt gtgacgcgtc cggaaacgtt tgatgtcatt 453541 gtggcgagca acttgttcgg tgatatttta accgacatca gctcaagcct gatgggaagc 453601 atcggcattg cgccttctgc gaacatcaat ccatccggca aatatccgtc catgtttgaa 453661 ccggttcacg gctcagctcc tgacattgcc ggacagggcc ttgccaatcc gatcggccag 453721 atttggacag cgaagctgat gctcgaccac ttcggagagg aagaattggg ggcgaaaatt 453781 ctggatgtaa tggagcaagt gactgccgac ggcatcaaaa cacgcgacat tgggggacaa 453841 agcacaacgg ctgaggtcac tgatgaaatc tgttcgcgct taagaaagct ctgatgaatc 453901 aggccggtgg cagatggctg ccccggcctg tccatttcct tacgaaaatt tccacgaaag 453961 tctaaccaag cagatccaaa tgctgtataa taatttggaa ttcttaggaa agcatcgggt 454021 gaaggaagtt gaatgcaaaa acaatcacgt taaagaaaaa aagaaaaatc aaaacgatcg 454081 ttgtactcag tatcattatg atcgcagctc tcatttttac gatcagattg gtgttttaca 454141 agccttttct tattgaagga tcatcaatgg ccccaacgct taaagactca gaaagaattc 454201 tggttgataa agcagtcaaa tggactggcg ggtttcacag aggagacatc atagtcattc 454261 atgacaaaaa gagcggccgc tcatttgtca aacgtttaat cggtttgcct ggtgacagca 454321 ttaaaatgaa aaatgatcag ctatacataa atgataaaaa ggtggaagaa ccatacttaa 454381 aggaatataa acaggaggtc aaagagtcgg gtgtaacctt aacaggtgac ttcgaagttg 454441 aggttccttc cggtaaatat tttgtgatgg gagataaccg tctcaattca ctggatagca 454501 gaaacggaat gggcatgcct tctgaggacg atatcatcgg tactgaatct ctcgtctttt 454561 atccattcgg tgagatgaga caggcaaaat aaaatgcaat gcaaaaagaa catggaacat 454621 gacggcaccg ataataaagc gccgtgcacg tttaaaaaaa tgatgatgaa acggtgcgga 454681 gccggctttc cgccccgttt tttatgatag aaagcgtttt gaagaaaagg gccctgttga 454741 aataaacaga atcaggattg gcgaagccgt gaagcgcatc gaattggtaa atctcaagat 454801 gggtatgctg tttttcccgc agttttttga taagaagcgc tacgtcaaac gacggctcat 454861 aattagggaa aaacaatagg accgggcagg ctggcatgtg atgaagagag tcgcgtatcc 454921 gggaaccgta ataacaaacc gatccgctca cctcaggcat actgctgcat ttccatgcga 454981 tagtagcccc cacgctgaat ccaatcacaa agatgtgccg tccggcgttt tgcctgatca 455041 cattctggat gatggtttct cccgttttca gcctttcgtg ttttgtaaat tgttcgtatg 455101 ccgttttttc ttctttcagt gtgtagactt catcctcgcc gagcaggttg ggcgtcaaca 455161 catcatatcc agccattttg atcagccggc ccatcttttt catatggctg tttacaccat 455221 atatttcgtg tgcgagaatg acaagcggtt ttgggaacat aacggcctcc ttttgtgttt 455281 tttccattat atcctatcgt ttcactttag gctgagatat aatggtcaaa aaaaggagat 455341 ataaaatgaa ctcattatct ttgcctcacc gctatccatt tttgtttatt gatggcgtga 455401 cggatagcga gcccggcaaa catgcggcag cttataagct gattagtgag aacgactggt 455461 ttatcactga tacgcaaaca gaaatgccgt tttcacttgt gattgaagcg cttgcgcaaa 455521 ccgcggcttt tacaggaatt acagatgaga acagcttggg attattgtct tcggtgaaga 455581 aagcggaaaa gctgggagaa gctgtgcctg gtgaccggct tgatcttacg tttgaagtca 455641 cgcgcaatcg gcgcgggttt gtgttcggac atgccaaggc atcagttgga gagcagcctg 455701 ttgctgaagc tgaaatcggc atctatattg aaaaatgaaa aaaacccttc acaacatttt 455761 gtgaggggtt ctattttgtg tcgtaatccc gttcgctttg agagttatct ctttgctggc 455821 gtttgtgttt ttcatcattc atattttcct tcagctcttc attaggaatc ggatcggtta 455881 agtcgttgtg ctcggggttt tcatttggtt tgttttgctg ttttttttct gtcatgtttg 455941 atcacctcac cgtttgtttt cctcttattc attctcctca aacataggaa atcgcttttt 456001 tgtcccgctg ggtataatgt attagaatag agagaagcac aacaaaaaga taaagagagg 456061 tacatatatg tctgttcaaa gagaagatgt agatatcaag ctgatcgcaa ttgatatgga 456121 tggtacactg ctgaacgacg agcagctgat ctcggatgaa aaccgcaaag ccattcgtga 456181 agcggaggat aaaggtgtgt atgtggtgat cagcacgggc cggacgctga tgacgtgcag 456241 ggagctggcg gaatcgctaa agctgtcatc ctttctaatc acggcaaacg gcagtgaaat 456301 ttgggattcg aattttaatt tggtggaacg gaagctgctt catacggacc atattcaaat 456361 gatgtgggat ttgcggaata agcacaacac taatttctgg gcttctacgg tgaataaagt 456421 atggagaggc gagtttccgg aaaacattac ggatcatgaa tggctcaaat tcggctttga 456481 catcgaggat gacgatatcc gaaacgaagt gcttgaggag ctgagaaaaa acaaagagct 456541 cgaaatcaca aattcaagtc cgacaaacat tgaagtcaac gcgcttggca tcaacaaagc 456601 tgcagccctt gccaaggtta cggaaaaact cggctttaca atggagaatg tgatggcgat 456661 gggcgacagc cttaatgaca ttgcgatgat caaagaagcg ggtcttggcg tcgcaatggg 456721 caatgcgcaa gacatcgtaa aagaaacggc tgattatatc acggatacaa atattgagga 456781 tggtgtcgct aaagcgattc gccattgggt actataaaaa aagagagtcc taagatggac 456841 tctctttttt agtttggcag gttttattct gggaccatgg taggttttct gacaaaagta 456901 tttcacaaac tgatatgatt cacttataat gaaataaagt tcaaaaattc ggaatagtcg 456961 ttccgaattt cgggacaata aatgacataa agcatatcgt ttgctttggc aggagggatt 457021 ctgtgtttca gattgattta aactgtgatt taggagaaag cttcggagcc tacaagatag 457081 gccttgacca agatatttta gagtatgtga catcagcgaa tatcgcatgc ggatttcatg 457141 caggagatcc tagtgttatg cgaaaaaccg tcgcgcttgc agcagaaaga ggcgtgaaaa 457201 tgggtgcgca tccgggcttg ccggatttac tcggttttgg gcgccgcaat atggcgattt 457261 ctcctgagga agcgtatgat cttgtcgttt atcaaattgg cgcgctctct ggctttctaa 457321 aagcagaggg acttcacatg cagcacgtca agccgcatgg cgctttatac aatatggcgg 457381 cagtcgatca aaaactgtcg gatgctatcg cgaaagctgt ctataaggtt gatcccggcc 457441 tgattctttt cggtcttgct gagagcgagc ttgtaaaagc gggagaacgg atcggacttc 457501 agaccgcaaa tgaagtgttc gccgacagaa cataccaatc ggacggcacg ctgacaccgc 457561 gctcccagcc ggacgcactc attgaaagtg atgatgccgc cgtcacccag gtcatcaaaa 457621 tggtgaaaga aggggcggtc aaatctcagc aaggacatga tgtgtcatta aaagcagata 457681 cagtctgcat tcatggagat ggagcccatg cgctgacatt tgcgcaaaaa atcagaaaac 457741 agctcaaagc ggctggaatt gaagtgacag ctatttcaga acagaggtca acataaagga 457801 ggaacaatag atggagcagc agaaaaagac agcaggaaaa aaagcgggca gctggtcatt 457861 gctgatgggc gccgcctttt taatggcgac atcagcaatc ggaccgggtt tcctcaccca 457921 aaccgcaaca ttcacaaaca cactcgcagc aagcttcggt tttgtcatct taatctctat 457981 tattttagat attttcgccc aaaccaatgt gtggcgcatc atcgcagttt ctggaaaacg 458041 aggtcaggaa attgcgaata tggtgcttcc cggactgggg tatttcatcg ccattctcgt 458101 cgtgcttggc ggactagctt ttaatattgg gaatatcgga ggggccgggc tgggacttca 458161 ggtgctgttc ggcattacac ctgaaacagg cgctttaatc agtgccgtta tcgccatttt 458221 gatttttgtc atcaaggaag caggaaaagc gatggaccgt tttacgcaaa tcgcggggtt 458281 cgtgatgatt attttaacgg tctacgttgc ggcgacgaca gctcctccgg tcggacaggc 458341 agtcgcaaat acattcgtcc cggaacacat cagcatattt gccattgtca ccctagtggg 458401 cggaaccgtc ggcggttata tcacatttgc cggaggacac cgtttgcttg atgccggaat 458461 taaaggaaag gaatccattc cgcaggtgac aaagagctcg gttgtcggca ttttaattac 458521 atctgtcatg cgtatcgctc tttttcttgc ggttctaggc gttgtatcga aaggcctgca 458581 catcgatgaa agcaacccgg cggcttctgt cttcaagctg gctgctggaa atgtcggtta 458641 taaaattttc ggattgatca tgtggtctgc ggcgattacg tctgttattg gagcagccta 458701 tacatctgtt tcatttttta aaaccttttc tccaaaaatt gaaaagaatt cacgcggtat 458761 tattatcgga tttattgtgg tttctacgtt agcttttgtc acaatcggcc agcctgcgaa 458821 gatcctcgtc cttgtcggtt cactgaacgg cttaattctg ccgattgcgc tcggaacgct 458881 gcttgttgcc gcctacaaga aaaacattgt cggtgattat aagcatccgc tttggctgac 458941 aagcacaggc gcgcttgtag tgattgtaat ggcagttatg ggaatctaca cgttatgtac 459001 acaacttcct caattgtgga gctgatataa gtggagcaat taaacaaaat ggcgccaaag 459061 gatgtacgcg ccctgatacg agaggggaaa ataaacgggc cgaccgcagg catgtccggc 459121 ggctacgccc aagcgaatct tgtggttttg aaaaaggacc ttgcgtttga ttttctgctg 459181 ttttgccagc gaaatcaaaa gccctgcccc gtgctggatg tgactgaagc aggttcgcct 459241 gtgccgtctc tggctgcgcc ggatgctgat atcagaacgg actttccgaa ataccgtatt 459301 tacaggcacg gtatcctaac ggaagaagta tctgatatta cgccatactg ggaggacgat 459361 tttgtcggct ttctgatcgg atgcagtttc tcctttgaac aggcactgat caataatggg 459421 atagctgtcc ggcatattga tgaggggaca aacgtctcaa tgtataaaac gaatatcgat 459481 tgtgttccgg cgggggcgtt tcacggacag atggttgtca gcatgaggcc ggttcctgaa 459541 cggctggctg tacgtgctgc acaagtgacc tcgcgttttc cggctgtgca cggagggccg 459601 atccatattg gcaatccggg agcaatcggg attcgcgatc tcgggaaacc ggatttcgga 459661 gatgccgttt ccattcgtga cggcgaggtt cctgtttttt gggcatgcgg agtgaccccg 459721 caagccgtgg ctatgaatgt aaagcctgaa atggtcatca cacatgcgcc ggggcatatg 459781 ctcatcacag atattcgaga cgagtcgctt gcggtgctgt agcctctcgt catcctgatg 459841 aacgagaatt aaaagaggtg agaaagatga ctgtacgata tcaaatcgaa cagctcggtg 459901 attctgcaat gatgatccga ttcggagaag aaatcaatga acaggtcaac ggcattgtcc 459961 atgcagcggc cgcttatata gaagaacagc catttccggg attcattgaa tgtatcccgg 460021 cttttacaag tctaaccgta ttttatgata tgtatgaagt gtacaagcat ttgcctcaag 460081 gcataagctc accttttgag agtgtcaagc gcgatgtcga agagcggctg gcagaaatag 460141 ccgaagacta tgaggtcaac cgccgtattg tagaaattcc cgtttgctat ggcggtgaat 460201 tcggtccgga tttagaagag gtggcgaaga tcaatcaact gtcaccggag gaagtaatcg 460261 acattcatac aaacggtgaa tatgtggtgt atatgcttgg cttcgcgccc ggttttcctt 460321 ttctaggcgg gatgtcaaaa cgcattgcag ctccgagaaa atcatcgcca agaccgtcga 460381 ttcccgcagg ttcggtcggt attgcgggat tgcagacagg cgtttatccg atttcaacgc 460441 cgggcggctg gcagctgatc ggcaaaacgc cgctggctct tttccggccg caggaaaacc 460501 cgccgacatt gctgcgggcg ggagatattg tgaaattcgt tcgcatctca gaaaaagact 460561 atcacgccta taaggaggag tccaattgag catgaaagta ttaaagcccg gactgctcac 460621 aacggttcag gatataggca gaacgggtta ccaaaaatac ggcgttctgg ccagcggcgc 460681 tatggacacg gtttcactgc gcattgccaa tctgttgata ggaaacggcg aaaatgaagc 460741 aggtctcgaa ataacgatga tggggcccgg tccgtcgttt catttttcaa aacagacact 460801 gattgctgtg acaggggcgg acttcacgct gcgtattaat gacgaggaag cgcctttatg 460861 gaagcctgtg ctcatcaagg aaaacagcac ggtcagcttt ggcccctgca aactcggcag 460921 ccgtgcttat ttggcggcag ctggcggcat tgaggtgcct gccgtcatgg aaagtaaaag 460981 cacatacgtc agaggaagca ttggcggact tcatggcaga gcgcttcaaa aagaagatga 461041 actgaacatt ggagagatgt cagctctttc gcaaaccatc ctttctcgct taagttcgca 461101 gcttggaaaa cagggatttg cagcaccgaa gtggtcagtc agccgcggca gatttctgcc 461161 attgaagaag aatcccgtca ttcgggtgct ggaaggaaag caatttgcct ttttcacaga 461221 agaatcaaaa acgcgttttt atgaagaagc atttcgtgtc acgccgcagt ccgaccgtat 461281 gggctacagg ctcaaaggag aaccgctcga actgaaggcc ccgcttgaga tggtgtcgga 461341 agcggtttca ttcggaacag ttcaggtgcc gcctgacggc aacccgatta tcctgcttgc 461401 agaccggcag acgactggcg gctatccgag gatcgcgcac atcatatccg ctgatcttcc 461461 gattgtttcc caaatcatgc cgggcgagca cgttcagttt gagcctgtgt ccctccagga 461521 ggcagaagcg cttgcggtag aacgggaaca gcatataaaa gaactgaaaa cgagaatgaa 461581 gatggaatgg ctgacatagc aaaggggatg aatgatgcag aataaaaata aaaccgtagt 461641 caaatctatg gcgctgctta atttgttttt gcataaacca agcctaacct taagtgaact 461701 ggtgtcgctg acgggaatgc cgaagacctc tgttcaccgg atggtcagct ccttggagga 461761 aatggggttc ctcagtcggg atgcgtccgg cgcttattcg ctgggattgg tgtttttgga 461821 attcggacag cttgtcgctg acaggctgga tatcagaaaa atagcgaaac cggtgatgga 461881 agagctgtgc cgggaagtgg atgaggccgt gcagttgatc atgagggacg gcaatgaagc 461941 gatatacgtt gagaaaatag aagggacaca gactgtgcgg ctgtatacgg cgatcggcag 462001 gcgttccccc ctatacgcgg gagcgtgcgc cagaagcatt ctgtcctttc ttccccgtga 462061 agaaatcgaa gcatacatca aacaaaccga gctcatttcg attggctccg gaacgattac 462121 cgatcccgaa aaactgcttc aggagattga tgcctctgtg caaaatggct atactgtcag 462181 ctattcagag ctcgaaaact atacggcggc gatcggcgcc ccgatcttta accatgagcg 462241 ccaggtggca gccggcatta gcattgcagg ctttgaagcg agatttacag aagacaggct 462301 gccctattta acagaaaagg tgaaggacgc cgctttacag atttcaagaa aaataggata 462361 tacataagta gccaatcttt tctctgctgc gtacattaac gtatcgacgt tcaagagtgg 462421 aggaaagaac atggtgcttc gatatacagc tctgggcgat tccttgacga cagggagagg 462481 ctccgggctg ttttcacccg gcttcgtcca gcgttttggg gacatgatgg aagctgactt 462541 gaaaacaaga acggcaataa acatatttgc cagatcaggt ctgaatacag aagagatttt 462601 gggactcctg tcatatccct atgtgcaaaa atgtattcga gatgctgata tgataacgat 462661 cacagggtgc ggaaacgatc tcatcgattc ggtcttagcc taccaaacct ctaaggatga 462721 aacgattttc agccgtgtat ccgcccattg ccatgagaat tttgaaaaga tgattgccaa 462781 agtcgccgag attaaaggag aaaatccttc cccgtacgcc attcgtgtgt tcaacttata 462841 caatccgttt cccgaaattg atatcgccgg caaatggatc acttcgttta attcacattt 462901 agaaacactt gcatcagcac cccatgtcaa aatcgcggat gcctatagca tcttcaaagg 462961 caaagaacag gaatatctgt cctttgacgg tgtccatccg aacagcaaag gctatcaagc 463021 gatggctgaa gccgttcaca agctaggcta taaagaatta tcagtttcat agaaaacgcg 463081 cctcatgaca ggcgcgtttt ttatgtgtga tcgaaatatt aaaagaaact taaaattctc 463141 tgtcttctgt tctacagaca aacaaagtgc gctagaataa tggagggcgt aggcaaatat 463201 agccataacg ttcaatattt cgtatataag gaaggatggt ccttttgttt cggattttta 463261 aaatgtcttt tgcggttatc attattatac tggcgcttat tgcttttaac tatacggaac 463321 acacctctgt aatccaatcg gtcatgctcg tctttcttgg tgcggtcatg tttatgcagg 463381 ggcttgaaga gcgcaaaaaa gaaaatgacg gctcaggcgc ttttaatatt tataccgccg 463441 tttttgtatg gtctgtctcc cttatcggtt ttacacttca tattatataa atctattaca 463501 catcctgaaa atgctcgacc gtcgggaacg gggtatagaa ccgatgaagc aaggctttcc 463561 actcttgata ctctgaagaa ccgcgaaagc cttccgtatg gtcctcaagt gtttcccact 463621 ccacaagaag cagatattta tgcgtttcct ccatgcattt tgataacgag tgagtgatat 463681 agcccttcat gccggaaata atcggcgcag cttgccggaa tgcatcctca aactcttgtt 463741 caaggccttc tttaatgtga agcattgctg cctctctgac catgctatcc cttctttctg 463801 tcttttcaaa tagtctacag caaacgatag gagatttctg caaaatcggt gaacttttcc 463861 ttcattttca aaaaaatctt gcacgcacca attcaattaa gagaaaataa caagtggaag 463921 gcaggggaaa gtcatgttaa aaaagtgtat tctactagta tttctatgcg tcggattgat 463981 tgggttaatc ggatgctcca aaacagattc accagaggat cgcatggaag cattcgtgaa 464041 acagtggaac gatcagcaat tcgatgacat gtatcaaagc ctgactaaag atgtcaaaaa 464101 agaaatctcc aaaaaagatt tcgtcaacag gtataaagcc atctatgagc aggccggcgt 464161 aaaaaatttg aaagtcactg cgggagaagt agataaggac gatcaagaca acaagacgat 464221 gaaacatatc ccgtataaag tcagcatgaa cacaaatgcc ggcaaagtca gcttcaagaa 464281 tactgctgtg ctgaaattag aaaaaacaga tgacgaggag tcatggaata tagattggga 464341 cccatcgttt attttcaagc agctggctga cgacaaaacc gtgcaaatta tgagcattga 464401 accgaaacga ggccaaattt acgataaaaa tggaaaaggc ttagccgtca atacagatgt 464461 tccggaaatt ggaattgttc ccggagagct tggcgataaa aaagagaaag tcataaaaga 464521 actcgccaaa aaacttgatt tgactgaaga cgacatcaag aaaaagctgg atcaaggctg 464581 ggtaaaagac gattcgtttg tgccgctcaa aaaggtcaag cctgaccagg agaaattagt 464641 ttctgaagcg acgtcattac aaggcgtaac aagaacgaat gtcagctccc gctactatcc 464701 gtatggcgaa aagacagccc atttgacagg ctatgtccgc gccattacag cggaagaact 464761 gaagaaaaag aaagaaggaa cgtacagcga tacgtctaac atcggtatcg ccggacttga 464821 aaatgtgtat gaagacaagc taagaggcac aactggctgg aaaatctacg tgccgcaaac 464881 cggggaagtc atcgctgaaa agaaagcaaa ggacggcgag gatcttcacc tcacaattga 464941 tatcaaaacg caaatgaagc tgtatgatga actgaaggat gacagcgggg cggcagtcgc 465001 gctgcagccg aagacaggcg aaacactcgc ccttgtcagc gcgccttcct acgatccaaa 465061 cggatttatt ttcggctgga gcgataagga atggaaaaag ctaaacaaag ataaaaacaa 465121 tccgttttca gcgaaattca ataagacata cgcgccaggt tctaccatta aaccgattgc 465181 ggctgctatt ggaatcaaaa acggcaccct taaagccgat gagaagaaaa caatcaaagg 465241 caaggagtgg caaaaagatt caagctgggg cggctattca gtgacacgtg tgtctgagag 465301 acttcaacaa gtcgatttgg aaaacgccct tattacgtca gacaatattt attttgccca 465361 gaatgcgctt gatatgggag cggacacctt tacaaaaggc ttgaagacat tcggtttttc 465421 agaggacgtt ccgtacgaat tcccgatcca gaaatcgtct attgcaaatg acaagcttga 465481 ttcagacatt ttgcttgcgg atacaggcta cggacaaggg caaatgcaaa tgtctccgct 465541 tcacttggca actgcttaca cgccatttgt tgacaatgga gaccttgtca aaccgacgct 465601 gatcaaaaaa gattcacaaa cagctgatgt ttggcacaag caagtggtca cgaaggaagg 465661 agcggcagac attacaaaag gtctgaaagg cgttgtggaa gatgagcgcg gatcagcgta 465721 tcagcctgtc gtgaaaggaa tcacagtggc tggaaaaaca ggaacagccg agctgaaaac 465781 atcaaaagat gataaagacg gcacggaaaa tggctggttt gtcggctacg attacgaaaa 465841 caaagacctg cttgtcgcca tgatgatcca aaatgtgcag gaccgcggcg gcagccacta 465901 tgtcgttgag aaagcgaaaa agcaatttca atcgaattaa aatgtctttt taaaaggagc 465961 gaaaggaaaa aggggatctg aggccgaatg aactagtaag ggggcaaaac ccggtttata 466021 caaagaaaag agggattttg catgcagcgt attcaattgg cggaggatct tcaattttca 466081 agagtcatac acgggctttg gcggctgaat gaatggaact attcagatgc tgaacttcta 466141 agcctcattg aatggtgtat cgatcacggc atcacgacct ttgatcatgc ggatatttat 466201 ggaggctata cgtgcgaaaa gctgtttgga aacgcccttg ccctttcgcc tggattaaga 466261 gaaaacatag agttggtcac aaaatgcggt atcgttcttg aatcgcctga acggcccgct 466321 cacagatcgc atcattataa cacaagcaaa tcgcatattt tggcatccgt tgagcaatcg 466381 cttatgaacc ttaggacgga ttatatcgat atgcttttga ttcacagacc ggacccgctc 466441 atggatccgg agggggtagc agaggcgttt caggccttga aatgctctgg caaggtcagg 466501 tactttggcg tttcaaattt taaagatcac cagtatcgga tgctggaatc atatttgcct 466561 gagaagctcg taaccaacca gattgagctt tccgcatacg aattagaaaa tatgctcgac 466621 ggcactttga acctgtgcca ggaaaaacgg attccgccga tggcttggtc gcctctggca 466681 ggcggcaaag tattcactga aaacacggat aaagaccgac gtgtccgtac ggcgcttgaa 466741 tccgtccaag gggaaatcgg cgccgcttca ttggacgagg tgatgtacgc atggctgtat 466801 acgcatccgg ccggcatcat gccgattgtc ggaagcggaa agcgcgagcg gatttccgcc 466861 gcgataaatg cgttgtcata caagcttgac caggatcaat ggttccgcat ttttacagcc 466921 gtacagggtt acgatattcc ataaaaagca tcagtttacc agctgatgct ttttcaatat 466981 tgtcacaccg cttagtgcca aattaccatt tataagtgat tgattctttc ttgaaagcgt 467041 tttatattaa aaggaaacct ctctatatcc tctactgcat ctccttgcga cttcatccgc 467101 acatcaagat tggctaggag gtctttttta tgtatatgac tgccagagaa caaaagctgt 467161 taaagcactt attattacaa aacagatata taaccgtaac tgagcttgct gagctgatgc 467221 aagtcagcac gagaaccatt cacagggaac tcaaatcaat taaaccgctg atggaaaccg 467281 tggggcttac gttagataaa cagcccggta aagggttgaa agcagtggga agtcccgagg 467341 gtaaacaaaa gctgcttact gatttatcat atgaacagca tgaatacagc gccgacgaac 467401 ggaaactgct cattctttgt tcgttattag agtctcagga gcccgtcaaa ctgtacacgc 467461 ttgctcatga tctccaggtg acgaatgcca cggtcagcta tgacttagat gagctcgaga 467521 agtggatttc tccctttgga ctgacactga tccgcaaaag aggttttggc atccagctca 467581 tagggccgga gaatgcgaaa cggaaaattg tcggcaactt gattgtgaac cgtctcgaca 467641 tccaaatgtt tttggaagcg gttgaattaa acatcaaagg aaaaaccgat tcttcagaga 467701 aaatgttcgg ggttgtcagc aaaggtgagc tgttaaaaat ggagcgcatc ttatttcagc 467761 tcaaagaaaa aatcgctttt tcattgtccg acagctccta tatagcgctc gtcgtccatc 467821 tgacgtatgc gatcgaacga attaagcttg gggaaactat caccatggag caaaatgagc 467881 ttgaggaact gatgaatgcg aaggaataca gctccgctct tgaaatcgcg ggcgagcttg 467941 aacgtgcctt cggcgtgacg attccagagg cggaggtcgg ctatattaca atccatcttc 468001 gaagcgccaa tcgaaaatac aaaacagaat acaaagcgca ggaaattgag ctggaaacag 468061 ccctgcaaac aaagcggctc attgctttta tttcagacaa aatcagaatg gatctgacga 468121 aaaactactc tttatatgaa ggcttgattg cccatttgga gccggccgtc agccgcataa 468181 aagaaaatat tgagatatac aatccgatga aggaacagat caagcgcgat tattttctgc 468241 tttatatggc gatcgaagaa ggtgtcgaaa agtattttcc gggcatgtcc ttttctgatg 468301 atgaaatcgc ttttatcgtt cttcactttg gctcggctct tgaaatcaaa aaagaagaag 468361 caaaagtgaa agcgcttgtc gtctgctcaa gcgggatcgg ctcctcgaaa atgcttgcct 468421 ccagactgaa aaaagagctg ccggaaattg aatcgtttga tatgtcatct ctgatcgagc 468481 taaaggggaa ggatgttcaa gcctatgata tgattgtgtc cactgtaccg attccttatg 468541 aaaacattga ttacatcatg gtcagcccac tattaaatga ggaagacgca aaccaggtca 468601 agcagtatat caagcggaag attcccctta ttcttaacaa aaaaagaagc tcgaaggaag 468661 aggcgcagca agctgatgta cctgacatgc tggaggcggc ggaaagcata gggcggtata 468721 tggaagttat ccaagatgtt ctgcgccatt ttacgctagc tcaactcaaa acaaacccgg 468781 accatagcat gcttctgcta gagctttttc aacagctgaa gaaggatggc ctgatccgtg 468841 atccggaaaa agccgcggtt tgcctggctg agcgggagaa acaaggggga ttgggaatcc 468901 ccggaacaaa catggcgctt tatcatctca aaaatgatga aatcgtcctg ccttttttca 468961 aaatgtttga tctcagcacc ccctatgaag tggatggcat ggacggaaat accctcagga 469021 tgacacgcat tctcgtcatg atggcgcctg gctcattatc tgctgaaggc tcggagattt 469081 taagcgcgat cagctcggca attatcgaga gcggagaaag catggcgggg tttcaggaag 469141 aaggaggaca agaattgtat cagcggttaa accgcatatt tttcacatgg atgaaagaaa 469201 aaaacatact gtaaacctgc atggcacacg tcaaaaattt ggcgtgtgtt tttctgtgga 469261 tggggaacaa aataagaaaa tgtgggacta ttttatcatt cagtattgga ataattccaa 469321 aatgaaatag ttttacaagt tatctttttt gggttaaaat gggtgaggta aggaagaaaa 469381 tctaacaaat tattgaagat tcaagagaat ataggagatg acgatatgga aacattacag 469441 catctgattc tgcatgacat gccgaatagc gaagaaatag aggctgtaaa aagcggagac 469501 catacactga catataaagg ttaccgtaaa cggattaatc agctggcgaa tgccatgctt 469561 caaaaaggaa ttcaaaaggg cgaccgtgtt gcattgcttt gcaaaaacgg ccatcccgcc 469621 tcaactgtta tgttcgccgc acttgaaata ggtgctgttg tcgtacctgt cagctggcag 469681 ctgaaaccat atgaaatgac aggcatttta aaagcaagtg aaccaaaagc gatgttttac 469741 ggagcggagt ttaaagagat actggatgaa gttcttcctg aattgtcctc actgtgtgta 469801 acaatggaaa caggaacagc ttacgaaaca tctgctgaat ttgaagcgct gtttgcaggt 469861 cctgatcatt tgccagagac ggaaatggtt tcacctgatg atacagcact tctgatgttt 469921 acatctggaa caacgggaaa cccgaaaaga tgcatgatta cacatggcgg catatacaga 469981 tacgttaaaa aatccaacag ctcaatagca cgtatgaagg gccttcgttt tctcgcgtgc 470041 catccgattt atcatacgag tgcgctcatt tgcatcatgc ttggaacgtt tgcagaaaca 470101 acatttgtgt ttacaaagga tcaagatcct gttcacatgc tgaaggtcat tgaagaagag 470161 aagattcaga ccgtgatggc tcttcctgtg ttctacacgt atttgcttga ggcgtgggaa 470221 aagcaccaaa ctgacttatc ttcgcttgtt attttaatga caggcggaac aaaagtgccg 470281 agcagcctaa taagccgcta tcttgatatt ggcattccgc ttgcgcatgg ctatggaagt 470341 actgaggctt ggggcatcag cacatggacg cctgatatgg gaatggataa agcggcatct 470401 gcaggaaaac ctgtggcagg tgttaaagtc aaagtggaag atcctctgac cggagaagaa 470461 cttcctcaag gagaaatcgg cgaaatcgtt gttcatactc cattcttatt taaaggctat 470521 gaagacaatc ctgaagcaac agcgaaagtg ctgcaaaatg gatggtttag aaccggagat 470581 tcaggatatg tagatgaaga tggctttatt ttcatcacgg gacgctacaa ggatgtcatt 470641 atttacggag gcgataacgt ctatcctgat caggttgaag aagttatcca gcagatcccg 470701 ggaatccttg aaacggctgt ggtcggtatt cctgacccgc tttacggtga aaaaccgaaa 470761 gcttttatcg tgaaaaatgg cggccagcgc atcacggaag aggatgtcat cgcattttgt 470821 aaagaacgcc tgtccgctta caaaatacct gaagttgaat ttgttaacga actgccgaaa 470881 aacaaccttg gcaaggtgaa aaaagacgtc ctgcgcaatc aggctgtaca ttcataaaag 470941 aagaagcccg tccactttat gtggcgggct tctttgcagt tgcacagacg gaaagctcag 471001 gcttaatgtt cttaaattgt atatcaatgt cttcgaagcc ggctgcttta aagtcagcaa 471061 tcatctgtct tccaaatgat ttggttttct caggactggc atccgcttcc cgcggctgca 471121 tcgtaatggc tgctttgccg cctggcttta atgcccgata aatctgtttt atgccttttg 471181 tttggtcatt ccaaatggtg tagttgttaa cggaaatcac tttatcataa aacgaggcgg 471241 ggagaggaaa tgtctcgatg cttccttgta tcaggcgtac gccctttggt ttcactctgc 471301 gggcggccag cttcagcatg gcctctgata catcaatccc atgaagatga acatccttct 471361 cgcgtttcag catctgctgc atgcagtatc ccgggccaaa cccgacttct aaaatgctgt 471421 ccccgcgcgt gatacccagc tgattgattg tccactgatt cagtgtttga ttttcagcag 471481 ccatgatgta cccggcaatc atgccgatga cgccctttgg cctgctgaat cttctagaaa 471541 gcatgttaat cattcagcaa ccaaccccct ttttgagtta atttcctctc agcgttccat 471601 gtgaaacatt tttctgataa agcaatgcga aggtgccaag ccatgtttat ccaaagagtg 471661 tgtgaggtac acaacaaata gacatgaaaa caaaggagga gaatcatcat ggcaaattat 471721 ccaaaagaac tgccggcaca aactcaaagt cgccagccgg gaattgaaag cgaaatgaat 471781 ccaagtccgg tgtatgagta cgaggattat aaaggagcag acaaattaaa aggaaaagta 471841 gctcttatta caggcggcga cagcgggatc ggacgcgcgg tttccgtcgc ttacgcaaag 471901 gaaggcgcag acatcgccat tgtgtataag gatgagcatg aagacgctga ggagacgaag 471961 aaacgtgttg aacaagaagg cgtaaaatgc ctgctgattg ctggtgacgt aggtgaagag 472021 gaattctgca atgaagcggt tgaaaaaacg gtcaaggaac taggcggcct tgacatcctt 472081 gtcaacaatg caggtgaaca gcacccgaag gaaagcatca aagatattac gagcgaacag 472141 cttcaccgca cattcaaaac aaatttttat tctcaatttt atttgactaa aaaagcaatt 472201 gattacctga aaccgggcag cgccatcatc aatacgacat ccatcaaccc gtacgtaggg 472261 aacccgacac tgattgatta tacagcgaca aaaggggcga tcaatgcctt tacaagaaca 472321 atggcgcagg cgcttgtcaa agacggcatc cgtgtaaatg cagtcgcgcc gggtccaatt 472381 tggacgccac taatcccagc tacgttccct gaagaaacag ttgctcaatt tgggcaagat 472441 acgccgatgg gccgtcctgg acagcctgtt gagcacgtcg gctgttatgt gcttctggca 472501 tcagatgagt cctcttacat gacaggtcag accctgcatg tcaacggcgg aaactttgtg 472561 acgacataag agggagtgag acatatgggc atcacgaaag aagaagtgaa cagctactat 472621 caaaaagcag ggattgtatt aacggacgag gaagtagacc aaatccagct gatggattac 472681 ggcttaggaa aagaaagaaa agtcgggctc cagctcttcg tctacgtcaa tacagaccgt 472741 tattgttcaa aggaattggt gctgtttccg ggacagactt gcccggaaca ccgccatcca 472801 ccggtcgacg gccaggaagg caagcaggag accttccgct gccgctacgg aaaagtgtat 472861 ctttacgtag aaggagaaaa aacgccgctt ccaaaagttc tccctcctca ggaagacaga 472921 gaacactata cggtctggca cgaaattgag ctagaaccgg gcgggcaata cacgattcca 472981 ccaaacacaa agcattggtt ccaggccggg gaagaaggtg ccgtcgtgac ggaaatgtca 473041 tcgacgagca cggataaaca tgatatcttt accgatccaa gaatataagg atgggcttaa 473101 cagcccatcc tttttgtatt gaaaaaaaca gaatcatcgc tataatgggt aaaaaaggaa 473161 agagggcgag gcaatgttca cttgcaaggt aaatgagcac atcaccatcc gattattgga 473221 gccgaaggat gcggagcggc tggccgaact cattatccaa aatcagcagc ggcttggcaa 473281 gtggctgttt tttgcggaaa atccaagcag cgctgacacg taccgagaaa caatcattcc 473341 agattggcgg cgccagtatg ccgacctgaa cggcattgag gcgggtctcc tttatgacgg 473401 cagcctatgc ggcatgatca gcctgcataa ccttgatcaa gtgaatcgta aggcggaaat 473461 cggatattgg attgccaaag aatttgaagg gaaaggcatt attacagctg cctgccgaaa 473521 actcattacg tatgcttttg aagagcttga gctgaatcgt gtggcgatct gtgcggctgt 473581 cggaaacgaa aaaagcagag cggttccgga gcggatcggg tttctagagg aaggaaaggc 473641 acgggatggc ttatacgtaa acggcatgca tcacgacctc gtctactaca gtctgttaaa 473701 gcgtgaatgg gaaggcgaaa aataaagagc acactttctt gtttaaatct tccccggatg 473761 tggaaaagta acagcggaga cgttaaaaag gagtgattcg agatgaatca gcaagacatt 473821 aaacaaaaag tgcttgatgt tctagatcac cataaagtag gttcgctcgc aacagttcaa 473881 aagggcaaac cgcattcccg ctacatgact tttttccatg acgggctgac gatttacaca 473941 ccgacaagca aggaaactca taaagcggaa gaaattgaga acaaccccaa tgtccacatt 474001 ttattaggct atgattgtga aggttttggc gacgcatatg tcgaagttgc cggaaaagca 474061 aagatcaaca attcggcaga actcaaggac aaaatatgga gttccaaatt agagcgctgg 474121 tttgacggca aggatgatcc gaatctggtg attcttgaaa ttgaaccgga ggatatcaga 474181 ttaatgaatg ccggggagaa aacaccggtc tcactcgaac tataaaaaat ttgtgttttc 474241 aggggcgata tgttattatg aatagctagt aagaaaaata agcaaataaa aaagaaagta 474301 aacttctttt ttctgttttg agagagaagc ttaccgcttc ccaagcagca taaccagctg 474361 cccttattct tttccttcat aacaaatcgc ccctaacgat gagatggaaa aaagactttt 474421 ttgttttaca attcacaccg gcgcggcttc ggagccgcag tgacgattga gaggtagggc 474481 tttcgttgtc ttgtgttcaa gaaatttcca tggtgtttac tttccagaat gattcttcgg 474541 aacaatgctt tatgaatcta acccgcctga cttggcggat gatataatct ttatttgcgt 474601 atagaaaaga ataagacaaa ccgcccggcg tacgccggac ggttttttta ttgcaaaaaa 474661 cacatcgtac tgaaacctcc ttgtcttctt tccagtctta tctctaggat gaaattggag 474721 gaagaataac gtgcatgtca ttacaacaca agtacttttt attttttgtt ttttattgct 474781 gattcactcg atagaaacct tagcctatgc gacaaggctt tccggagctc gcgttggatt 474841 tattgcgtcc gcgctttctc tgtttaatgt catggtcatc gtatccagaa tgtcgaatat 474901 ggtgcagcag ccctttactg ggcatttaat tgatgatgct ggaaaaaacg cactggcgat 474961 tgtaggggag cagttccgct ttttaatttt cggatcgaca gtcggcacca ttttgggcat 475021 tatcctgctc ccgtcttttg tcgctctttt ttcacgggcg attattcact tggcgggcgg 475081 cggcggctcc gtttttcaag tattccgaaa gggattctcg aaacaaggat tcaaaaatgc 475141 cctttcctat ttgcgtctgc cgtccatttc atatgtaaaa ggatttcata tgcgcttgat 475201 tccgaagcgt ttgtttgtca tcaacatgct gatcacatcg atttatacga ttggtgtgct 475261 ttcggcttta tacgcaggcc ttttggcgcc ggagcgcagc acgacagccg tcatggcttc 475321 gggtttgatc aacggaattg caacgatgct gctggctatt tttgttgatc ctaaggtatc 475381 cgttcttgct gatgatgtgg caaaaggaaa acgaagctat atctatttaa aatggacctc 475441 tgtcacaatg gtcacatcaa gggtggcggg cacactcctc gcccagctca tgtttattcc 475501 cggggcctac tatatcgcgt ggctgacaaa gtggttttaa taagaaaggc tggatcataa 475561 agatccagcc tttttgcgct tccttattta tagttcctta atccgcggtc gtacaaaaaa 475621 tttccgaatg ggacgaaagc ggcgatgaag ccggcagctg accatttcag cggccatttg 475681 acagagaagg ttgcataagc caagacaagc aaatacaaaa tgaacaaccc gccgtgaacc 475741 gaaccgacaa ttgtcaccgc aagcggaagg cctgcccaat atttaagcgg catagcgatg 475801 aacaacagga ttaagagtga cattccttca ataaaaccca tcgtgcgaag tcttccgatc 475861 ggcgtgtgca gcataaatcg ccctccttgt ggacacgttt tcattttata ctataaacaa 475921 tccggggggg catatgacag ctttcaaaaa atgttcggaa aacattcatt tttacatgcc 475981 ttttctaggg aactgtactt gtcatttaca aaaatacccg agataatgtg tacaaaatca 476041 aaaaagaagg atgttgaaat gaaacttgac cagattgatc tgaatatcat tgaggagctg 476101 aagaaggaca gccgtttgtc gatgagggaa ttaggcagaa aaattaagct gtcgcctcca 476161 tctgtaacag aacgggtaag acagcttgaa tcgtttggca tcatcaagca atacacgctg 476221 gaggtcgacc agaaaaaact ggggcttccc gtttcctgca ttgtggaagc aaccgttaaa 476281 aacgcggatt atgagcggtt caaaagctat attcaaacat tgccgaatat tgaattttgc 476341 taccggattg cgggtgcagc ctgctatatg ctgaaaatca atgccgaaag cctcgaagcg 476401 gtagaagatt tcattaacaa aacatcgccc tacgcgcaaa ccgtcactca cgtcattttc 476461 tcagaaattg acacgaaaaa cgggcgcggt tagagagtgc cgcgcgaagt ctgttataat 476521 aacaggatga gcgtgaaaga aagagaagtg atcaagcatg tcaaaaacag ttgtattagc 476581 tgaaaaacct tcagtcggcc gggatttagc ccgggtactg aagtgccata aaaaaggaaa 476641 cggttatctc gaaggcgatc aatatattgt gacttgggct ttaggccatt tggtgacgct 476701 tgctgatccg gaaggctacg gaaaagaatt tcaatcatgg cgcctagagg atctgccgat 476761 tatcccagaa cccttgaagc ttgtggtgat aaaaaaaacc ggaaagcagt tcaatgcagt 476821 caaatcccag cttacccgta aagacgtcaa tcagattgtc atcgcgactg acgcaggccg 476881 ggaaggtgag cttgttgcgc gctggatcat tgagaaagcg aatgtccgaa aaccaatcaa 476941 gcggctgtgg atttcatctg tgacggataa agcgatcaag gaaggttttc aaaagctgcg 477001 cagcggcaaa gaatatgaaa acctgtacca ttctgccgtc gccagagcgg aagcggattg 477061 gattgtgggg atcaacgcca cccgtgcact taccacaaaa ttcaatgccc agctctcatg 477121 cgggcgtgtg cagactccga cgcttgccat gattgcaaag cgcgaggcag acattcaggc 477181 gtttacgccc gttccgtatt acggcatacg tgctgcagtc gacggcatga cgctgacgtg 477241 gcaggataag aaatcaaagc agacgagaac gttcaatcaa gatgtaacaa gccgtttgct 477301 aaaaaatctc caaggaaagc aagcggtcgt agctgagctg aaaaaaacag cgaaaaaaag 477361 ctttgcgcct gcgctttatg atttaacgga gctccagcgt gacgcccaca agcgcttcgg 477421 tttttctgcc aaagaaacgc tttctgtcct gcagaagcta tatgagcagc ataagctcgt 477481 cacatatccg cggacggact ctagattttt atccagtgac atcgtcccga cgttaaaaga 477541 ccgtctggaa ggcatggaag taaaaccgta tgcccaatat gtcagccaaa ttaaaaaacg 477601 cggcattaaa tctcataaag gatatgtcaa tgacgcgaag gtgtcagacc accacgcgat 477661 tatcccgacc gaagagccgc tcgttctcag cagtctgagt gataaagaac gaaagctgta 477721 tgacctgatt gcgaaacgtt tcctggctgt attaatgcct gcattcgaat atgaggaaac 477781 aaaggtcatc gcagaaatcg gcggagaaac ctttacggcg aaaggcaaaa ccgtgcagtc 477841 gcaagggtgg aaagccgttt atgatatggc ggaagaggat gatgagcagg aggatgacag 477901 agatcagaca cttcctgcgc ttcaaaaagg cgacacactt gccgtccgca cgttaacgga 477961 aacaagcggc caaacgaagc cgcctgcccg ctttaatgaa gggaccttgc tgtcagcgat 478021 ggaaaaccca agcgcgttta tgcagggaga agaaaaaggc ctcgtcaaaa cgcttggaga 478081 aacaggcggc ctcggcacgg tggcaacgcg tgccgacatt attgaaaaac tgttcaacag 478141 ctttttaatc gagaaaaaag gccaagatat ttttatcaca tctaaaggaa aacagctcct 478201 gcagcttgtt ccggaggatc tgaaatcacc ggccttaaca gcagaatggg agcaaaagct 478261 gtctgcgatc gcggccggca aattgaaatc ggctgttttt attaaagata tgaaggctta 478321 cgctcaccaa acggtaaaag aaatcaaaaa cagcagccaa accttccgac atgacaacat 478381 tacgggaacg gcatgtccgg aatgcggcaa aatgatgctg aaagtaaacg gcaaacgcgg 478441 gacgatgctc gtgtgccaag atcgtgaatg cggaagcaga aaaacgattg cccgaaaaac 478501 aaacgcacgc tgcccaaatt gccataaaag aatggagctt cgcggccaag gcgagggcca 478561 aacctttgcg tgtgtgtgcg gtcaccgtga aaagctctct gtatttgaaa aacgaaaaaa 478621 caaagacaaa gcgcgtgcta ccaaacggga cgtatcctct tatatgaaaa aacaaaataa 478681 agatgagccg attaacaacg cgctggcaga acagctgaaa aaactcggtt tggataaata 478741 ataaaaaaac ctgtgcctat cgcacaggtt ttttattgga cttaggtcct gttttcttaa 478801 tgttcaaaaa gggaaaaaaa agctagcaat ctgcattttt tttcttttat agtaaatgta 478861 ctttgtaaca tggcagtcat attttcgtct ataactattt gtgagcgtct gatttgcttc 478921 aggcgacaaa gggggatttg cctgtgaggc atgtactaat tgctgtcatc ttattcttct 478981 tatctatcgg actttccgca gggtgtgctg aagctggaaa caagacccaa aatcagtcgg 479041 cgacagaagt gaatgccagc ccgctccagc cggcggaata tttcatctat cacaatttaa 479101 tgaatgacaa agggctgatc aaaaccgatt tttcagacca gccttcttac ttgtcggaat 479161 ctctcggact gtggatggag tttctgctca gcaaaaatga cgcaccacat ttccaggatc 479221 aatatcagca tctgactgat tcatttctga tgagcaatca cttggtgacg tggaagattc 479281 aaaatggcca agcgagcggg acgaatgcgc tgatagatga tatgagaatt atgctgtctc 479341 ttgaccaagc cgccgcaaaa tggggccgca gcgactacgc gcaaacggct agggatatcg 479401 gcacgtcttt gaagacatac aatatgaaca acgggttttt tacagacttt tacgactcac 479461 aggccgcttc aaaggatgtg acgctttcat acgtcatgcc tgatgcctta gctgtcttaa 479521 agaagaatgg aatcatagac gaagaaacag aacagcggaa tgccaatgtt ctctattcag 479581 ctcctttaaa aaatggcttt ctgccgaaga catacagctc ggagacgaag gaatacacat 479641 atgatagtga aatcaacctg attgatcagc tttacgctgc ttggcatttg ccggaagggg 479701 atgaaaaagc atctgtttta gcggactgga tcaagcagga atttcagaaa aacggaaagc 479761 tgtacgggcg gtattcggca tatacgaagg agcctgccgt ccaatatgag tctccatccg 479821 tatatgcctt agccgtattg tttttgacaa aacagcatga aaacagttct gtcatcaaag 479881 ccatatatga tagaatgaat gactttgaaa ttcatgatcc ggtgaaatcg tattatggag 479941 gctatatgag cggcactcag acgcattcat ttgacaatct gctgccgctg ttagccgaaa 480001 ggaagctttt taatgaaaat atcattcagt gaatcacaaa aattatttgc ttatttttca 480061 gggctcatcg cggccctgtc tttgtttatt tattatgtgt cagcccagca atcagaaggt 480121 gctctgatcc tttgcatcac atttggcgtc atcgccgcag gcatctggtt cggcccgatt 480181 tacgcgctgg cagtgacctt aatcgtactc tttgttctcg gcaccttaat gatgtttttc 480241 cagactggac agacatcgct ctttccggct gaggaagggc tgcgaatgct tgtcgtgtgg 480301 ggaatcgcgc ttttgctgtt ttcttttatt tctggaagaa tccacgatat tacagcagag 480361 cttcggcgct caatgacacg gcttcaatcc gaaattaaaa gctatgttgc tgttgacaga 480421 gtgactggtt ttgataacaa gcaaaggatg aagctggaac tttcagaaga aatcaagcgg 480481 gcggagcgct acggcaattc ttttgtgttt ttgctgctcc atatgcatta tttcaaagag 480541 tttaagtctt tgtacggtga aaaagaaacg gaccgcctct tccaatatgt cggtcagcaa 480601 atcaggacaa gcgttcggga aacggataag aaattccgtc cctctgacga gcgtatcggg 480661 atcgtgctga cgcacacgcc tgctgaacat atgccggccg ttctgactaa gctgaagaaa 480721 caattggata catatcagct ggaaaatgga aagtatgtgt cgcttacgtt ccacgtttgc 480781 tatttgccct accgcaacga tatccaaaca gctgatcaat ttttagaaga actggaaaac 480841 gagatgatga tgaatgaact ataaaggaat cacattgcta tgcgtcatga tgcttctatt 480901 ttcagctatt gcgtcttttc ccgtttctgc gcaagcgaaa gatcaggatg ccggcattct 480961 catcatctac tcaaccttgg acggcaaaga gtcgtcacaa gtcaaaatgc tcgatttgct 481021 tgcgggccac tttacatccc atgtgacagt caaaaaagat tcagacgttg aagcgtcgga 481081 tttcaaaggg aaagaccatg tgatttatta cggccaaacg aaaagaaagc tcagccaaaa 481141 attgctgtct cttatcagcg gcgtgaaaaa accggttgtc gccattggct ataacgcagg 481201 ccaaatcagc caattttctg ggctttcatt agcccgcaaa gaaaatgtgt ttcaggttca 481261 cagcaggtca gaaaaggccg atgtgtctct ggaaagcggg cttaacgtgc tgagtgtatc 481321 aggcctgaaa ggaacggcgc tttacacctt caaagcggat gaaggcacaa cgcattcttt 481381 tatatggaaa acaaaaaaag ggaatgtgta cattggatta acaaatttgt taaatgacaa 481441 tttgatcgtg gcgaaacagc tcagagaagc tttcggagag aaggcgggga cgacgttatt 481501 gtatttgcgt ctcgaggata tcagcccgat gtctgatgaa aaactgctgc ttcaagccgg 481561 tacatacctg cataagcggc atattccttt tatcctggcg gtcattccgg tttacttgaa 481621 tccggaaaca ggcgacaaag tgtatttgtc taatcaaccg aagatggtca aggtgctgaa 481681 gaagctgcaa agcatgggcg gcagtatcat agttcacggc tatactcacg cttatcgcta 481741 cagtgaaaca ggagagggat ttgaattttg ggatgcaaag gcggatcagc cgattacatc 481801 cggaaatgcc gaagaccccc cgtccatttt ggagaaagaa caggacttcc cgaacgaaca 481861 agcctatcac agctatcttg aaccatttcg ggaaaaggaa gaaacgtata caaaacaaaa 481921 actgacgcgt gccattgagg atttgacatc atcgggtctt tacccgctgg cgtttgaagc 481981 gccgcattac acgatgtccg aatatggcta tcaaatcgcc tcgcagtatt ttacaagcat 482041 tttcggccag gtccagctca gcagcacaac atggaaaaca tccggtgcac ctccgtttgt 482101 gactgctcct tcgatgctgc acggaatgac gctttatccg gaaacgatcg gctttgtcga 482161 cacatcgaag caaaacccgc tcggtgagat ggaggagcat atctcccaga tgattgattt 482221 tgaaggcgga gtagccggag gattttatca cccgtacctt gggatgaaat atctgcctga 482281 gctggttgat cagatggaac gcattccaga cagtgaatgg cttgatttaa agaaaacgaa 482341 acaaaccgtc aaaacagaca aagtggaaat tcatacaagc ggtgacggaa cgattcaggt 482401 gaaaaacggc gtaagcccca tttacgagtt tttcgatcat caccggcaaa cccctctgga 482461 aaaggcgtta tggattctct ccgctgttgt gctcttattt gtcatcatgt ttgtcagtta 482521 tacgttttac ttgagagcca cattgaaaaa acgaattttt aaggagagaa gaagccttgg 482581 gtaatacgct gttctttatc tcgctaagtt taatatgggt tatgcttctc taccacatgt 482641 tcctcatgca gggcgggttt cgccactata tgaccttcga acggaatatc ccgaagtgga 482701 gagaaaatat gaaggaactg ccgaaggtca gcgtcctcat cccggcgcat aacgaagagg 482761 ttgtgattcg gcagacgctg aaggccatgg tcaaccttta ttatccgaag gaccggctgg 482821 agattatcgt cgttaatgat aattcatcag accggacggg tgatatcgtc aatgaatttt 482881 ccgagaaata cgatttcatc aaaatggtga ttacgaagcc gccaaatgca ggaaaaggaa 482941 aatcctctgc acttaactcg ggttttgccg aatcgaacgg cgatgtgatc tgtgtgtatg 483001 acgccgacaa cacgcctgag aaaatggccg tgtattacct cgtgctcggc ctgatgaatg 483061 acgaaaaggc aggcgccgtg gtagggaaat tccgcgtcat caatgcggca aagacgctgc 483121 tgacgaggtt tattaatatc gaaacgatct gttttcagtg gatggcccag ggaggcagat 483181 ggaagtggtt caaaatcgcc acgatcccag gcaccaactt cgcgatccgc agaagcatta 483241 tcgaaaagct cggaggctgg gatgacaaag cgctcgctga ggatactgag ctgaccatcc 483301 gggtatataa tctcggctat cacatccgct ttttccctgc cgccatcacg tgggagcagg 483361 aaccggaaac atggaaggta tggtggcgcc agcgcacccg atgggcgcgc ggcaatcaat 483421 atgtcgtgct caaatttttg gcgcagtttt ttaagctgaa acgaaaacgg attatctttg 483481 atttgtttta ttttttcttt acgtacttcc tgtttttctt tggcgtgatc atgtcaaatg 483541 cgatttttgt agtgaatttg ttttatgatt tgcatttgtc tgttggattt ttggcaatga 483601 ttctctggat tttggcgttt ttcttattta tgacagaggt catgattacg ttgagcattg 483661 aaaaaacaga aatgaacaag caaaactttt ttatcgtatt tctcatgtac ttcacatact 483721 cgcaggcatg gattgtgctt gttatctact ctttattcgt agaaatcaag caccgtttat 483781 tcaagcaaga ggtcaaatgg tacaagacag aacgatacaa tcaacataaa agcgggtgac 483841 ctttttgaaa caaataatga tttttctcac aagcttcatg ctgctggcga tgactggaca 483901 aacggctctt gccaaagacg tacaggtcag cggttcgctc cttgggaaaa gcagccaaga 483961 acaagccaaa cagcaggtgc tgacaagcga gctgattaca ctgtatggat caaaagacag 484021 cgcagagctg acgtatcaga tcccggcagg cgcctcttcg ggcaatcagc aattggtaat 484081 cgaatacgag gcatcaaatc ttttaatttc tccatcatcg ttaacggttg tcattgatga 484141 tgaaccggtc aagacgttaa agcttgatgg tgattccaaa cggaaaacag tgaagctgaa 484201 tctgaataaa agccagtctg cgcaaggcta tcacaacgta tcgctgaaat tctacggcgt 484261 aatgaaagag ggcgtgtgcg tcagacagga tacatcaggc aactggatca aaatttatcc 484321 ggacagccgg ctgacacttg ctgacagcag tgaagcgaag ggaacgtcgc tggaccatta 484381 tccgtatcct ttcgcccaat ctggaaatac agcggaagaa acagctatcg tcattccgga 484441 taacccaagt tcagcagaaa tagaagctgc tgttaaaaca gaaggctatt tgaaaacggt 484501 ggacagcagt gtcagtattg cgtatgtcac ggaatctgaa ctgaaaaaaa tcgataagcc 484561 gacgattgtt atcggcgtgg acaagcattg gaacggcaaa gtgaaaaaac tgttgaaaca 484621 agccgggcta caggcaaaag gagaaaacct tctgcttgcg gagcgggtgc tgaaagcaga 484681 gggcaaacag cagccggttc tgtttgcgca agcggcgtcc gaggacgcgc tcacaaaaaa 484741 aatcagcgtg atgacagatc agacatatac aggccagctc agcggcgata cactttcaat 484801 cagcaagctt cagcagactg aaaaaaaaga aagcgataag ctgacccttg agaattttgg 484861 agcgggtgat atcacaattg gagccgacaa aacatcttca gcacattatt tttatccggc 484921 ttcggctgtt ttagatgaaa accaatcggc gaagctgtcg cttaaactga aaaagtctga 484981 aacgattcaa gcctcaacgg ctgaaaacga gtcagcctct caggctgcag aactgaaagt 485041 gatgatcaac ggccagccgc actcggtccg gcttgatgaa ttaggaaaag aagataaaaa 485101 cggattctat catgtcacag tgaaagtgga ccctaagctg ctgcaaaaaa accgctacat 485161 tgatattcag ttcgtcacga ccggtttaaa ggaaaacaac ccttgtaaca ccactgatga 485221 agaaaagtgg gtttttatcg ataaaaacag tacattatca tacgccatca aaggcatgtc 485281 cccgtcagcg gattttcaag agtggccgct gccttacgcc ggaaaccagg atcaaacaac 485341 gttaatcgtg cttcctgaca ccgtaagcca atcgaagcta gaggagcttt ctctcgtaac 485401 agaatccttt ggcaacgaag cacagcattc atatacggta aagaaatcat ctgacgttac 485461 agcaaatgat gcgaaaggac gaaacctcat tttcatagga gggatcaatc aattttctct 485521 tctgaaggag aaatcatcag atctgcttgt gccgcaggaa aagaacggct cgtttgatgt 485581 atctagtttc gagatgctga atgagacgac aaaacaagtg gtatttaccc aagcatcggt 485641 ttgggattca cgctatacaa tggctgtctt tgcaccgtca aaaggagatg gcacggctgt 485701 cacaaaagag atcatcagtt atctgaacag caacgatgag tcggcaaccg tccttaatga 485761 aacaaacagc cagcaggtgt ttacaaacca ccagcagctc aaatcggaaa caaacagttc 485821 cgatgcagaa caaccaacac aggatcatag ccagaaatgg atgtatattg gtgtgctggc 485881 actcattatg gtggttgcgg cagtgttcat ttggattgcc gtaagacgca aaaaaagaaa 485941 gacagataca gaataaaaca gaggcgattt tagcctctgt ttttttattt ttggtaagta 486001 aattccattt gtggaacctg tcattttatt tttttctctc agccaataag cctctttaca 486061 acgtgcggga acgggagtat gatctctttt agaaaacaaa tcgcttaatc tgaaatcaga 486121 gcgggggacc caatagaacg gctttttgcc gttggggtga atccttttta ggtagggcta 486181 actctcatat gcccgaatcc gtcagctaac ctcgtaagcg ttcgtgagag gagatgaatg 486241 aaacctgtgt tcgatgttat ggcacagggg catccgtttg cctctgtgtt ttttgttgtt 486301 catttttgaa tgcaaatcgc atacagagac atcatagcag aaaggactat catcaacatg 486361 tgagagcaag acactgatgg atgttttatt gttttaattg aaaaatgaga aattaaaagg 486421 ggaagacatc gatgtatcat tcaatcaaac gttttttgat tgggaaacca ctaaaatccc 486481 aagcagctgg agagcaaaaa ctgacgaaat taaaagcctt ggctatgctt tcctcagatg 486541 cgctgtcatc tgtcgcatat gggacagaac aaattctaat cattttggca acaatcagtg 486601 cagccgcatt ttggtactcc attccgattg cggttggcgt tctcatcttg ctgctcgcac 486661 tgattctttc atacaggcaa attatttacg cttatccgca gggcggcggg gcgtatatcg 486721 tttctaaaga aaatctcggt gaaaaaccgg gattgattgc gggcggttca ttgcttgttg 486781 attatatttt aacagtagcg gtaagtattt ccgcaggcac ggatgccatc acgtcagcct 486841 ttcctgcatt gcatgattat catgtgccga tcgctatttt tctcgtgtta gtgattatga 486901 ttttgaacct gcgcgggctt tcggaatcag catccatact tgcctacccg gtttatctgt 486961 ttgtggtggc gcttttggtt ctcattgcag tcgggttgtt taaacttatg acaggacaaa 487021 tagaccagcc agcccatcat acatcgctcg gcacacctgt agccggcatt acgctatttt 487081 tgctgcttaa ggctttttcc tccggatgct cagcgttgac cggggttgag gccatttcta 487141 atgcgattcc tgcattcaaa aacccgcctg cgcgaaacgc ggcaagaacg cttgcgatga 487201 tggggatttt gctggcgatt ctgttttccg gcatcacggt tctcgcgtac gggtatggta 487261 cggcgccgaa acctgatgaa acagtggttt cacaaattgc gtccgaaacc tttgggcgga 487321 atgtgttcta ctatgtcatc caaggtgtca catcgcttat tttggttctt gcggcaaata 487381 cgggattctc agccttcccg cagcttgcct tcaacctggc gagagaccag tatatgccgc 487441 gaatgtttac agtcaggggc gaccgcttag gcttctcaaa tgggattatc tttttaggct 487501 ttgcctccat tgttctcatt atcttattcg ggggacagac ggagcactta atcccgttat 487561 atgctgtggg cgtatttatt ccatttacgc tttcacaaac cggcatgtgc atgaaatgga 487621 tcaagcaaaa accaaaaggc tggatcggaa aaatgctgat caactcctgc ggcgctctga 487681 tatcatttat ggttctatcc attctgtttg tgacgaagtt taatgtcgta tggcctgtgt 487741 taatctttat gcctatcgtc gttttgctgt tttttgcgat taaaaatcac tatactgcgg 487801 ttggtgaaca gcttcgcatc gtagacaaag agccggaaga aatcaaaggc accgttgtga 487861 ttgtgcctgt ggccggtgtc accaccgtcg tgcaaaaatc gattcactat gcgaaatcac 487921 tgtccgatca ggtgatcgcc gttcacgtgt catttgacag agaacaggaa aagaaattcg 487981 aaaaacgttg ggaagagctt aataacggag tgcgtctcgt gacgcttcac tcctcttaca 488041 gaagccttgt ccatccgttt gataagtttt tggaaacagt tgaggcaaaa gcgaagaagg 488101 agcagttttc cgttatggtg ctgtttccgc aatttataac gaaaaaacgc tggcacacca 488161 tccttcacaa ccaatcggcc ttcctcctca gagtccggct gttctggaaa aaggacataa 488221 tggttgccac actgccgtat cattttaaaa agtaaagctc taggaccaag ggaatcacct 488281 tggtcctttt tagcgggaaa aggaggtatg ggggtgtata cacaaggtgc ttttgtgatc 488341 gtattgaacg aaagtcagca aattctgctg gtgaaacgaa aagatgtccc tctatgggat 488401 ttgccgggcg gcagggttga tcccggggaa tcggctgagg aagcggcagt gcgggagata 488461 ttggaagaaa cgggatacaa tgcagcgctt tctgcgaaaa taggtgttta ccaaaggcca 488521 aagtttcaag atgaacagca tctgtttttc ggaagcatta caggcggaca agcaatggct 488581 gacggcacag agacagcggg attaaagtgg gtttccccgg ggcgtttgcc gctttttatg 488641 gtgccgaatc gaaaaaggca gatcaatgat ttcaagaacg gcgctcaaga tgtaaatgtc 488701 accgtcaagg atagcgggtt gctcgcggcg atcgacctgt tgaaaagaag actgggcaag 488761 tgattcaggt ctccgggttt taaagccttt ctcctgtggt attgaaaaaa ggaaaaagga 488821 ggatacgtta tggcacacaa aactgcagga caagcaatga cagagctgct tgagcaatgg 488881 ggagttgatc atgtatacgg catccccgga gacagtataa atgagtttat cgaagaatta 488941 agacacgaaa gaaatcaact gaagttcatt caaacccgcc acgaagaggt agcggcactg 489001 gcagccgcgg ctgaagcaaa actcaccggc aagatcggag tctgtctgtc aatcgcaggg 489061 ccgggagcgg tgcacttatt aaatggttta tatgatgcta aagccgacgg cgcccctgtg 489121 ctggcgattg caggacaggt ttcttctggc gaagtcggac gggactattt ccaggagatt 489181 aagctggagc aaatgtttga ggacgtggcc gtgttcaaca gagaggtaca tagcgcggaa 489241 tcacttccgg atctcttaaa tcaggcgatc aggaccgcct acagcaaaaa aggcgttgcg 489301 gtattgagcg tgtcagatga tttgtttgcg gagaaaatca aacgggagcc cgtgtatact 489361 tcaccggtgt atattgaagg gaacctagaa ccgaaaaaag aacagctcgt cacctgcgcc 489421 caatatatta ataacgctaa gaaaccgatt atcctggcag ggcagggaat gaaaaaggcg 489481 aaacgggagc tcttagaatt tgcggacaaa gccgccgctc cgatcgttgt tacactcccg 489541 gcaaagggtg ttgttcccga taagcaccca cattttctcg gcaacctcgg tcagatcgga 489601 acaaagccgg cttacgaggc aatggaggaa tgtgatttat taatcatgct cggaacgtca 489661 ttcccgtacc gtgattattt gcctgatgac acgccggcga tacagctcga ttcagacccg 489721 gcaaaaatcg gaaaacggta tccggtgaca gcgggccttg tctgtgattc ggctctcggt 489781 ttgcgcgaat tgacagagta tattgaacgc aaggaagaca gaagattcct gaatgcctgc 489841 acagaacata tgcagcattg gtggaacgaa attgaaaaag atgagacaga ggcaacaaca 489901 ccgcttaaac ctcagcaggt cgtggcccgt cttcaggaag cggcagccga tgatgcggtg 489961 ctctctgtag atgtcggcac tgtgacagtc tggatggcgc gtcatttcaa aatgaacgcg 490021 aatcaggatt tcatcgtttc cagctggctt gcgacaatgg gctgcggcct gccgggagcg 490081 attgcagcga gcttgtccga accggaacgc caggcgatcg ccgtctgcgg tgacggggga 490141 ttttccatgg tcatgcagga ccttccgacc gccgttaaat ataagctccc gatcacagtc 490201 gttattttaa acaacgaaaa tctcggcatg attgagtacg agcagcaggt caaaggcaat 490261 atcgactatg tcacaaaact tcaaaatgtc gactatgccg catttgcaga aagctgcgga 490321 gcaaagggca tcaaagtgac caaagcggaa gagcttgcgc cggcttttca tgaggcgctg 490381 cactctgacc aaccggtcgt agtggatgtc atgattggaa acgaaccgcc gcttcctggc 490441 aaaatcacct acgggcaggc gaaaggcttt agcaagtaca tgctgaaaaa cttcttcgaa 490501 aaccaaaaat ttgaaatgcc gtcactgaag aaaagtttga aacggttatt ttaaaaaaac 490561 aggggcccta agagcccttg tttttttttt tttttttgga aacaaatgta ttttcagcat 490621 gtttgaattc ataaaatgat cggtatatgt attaggaact gatttcgcca tactcgaaac 490681 agacaaaagg acaaatgcat cttgtttcaa aggaagatgc atttgtcctt gcatgcttat 490741 tcttatcaaa tcttacagaa ctcttctcat aataggttat ttttcttttt tcttcagccc 490801 gaagaagaaa ggaaaagcag aaccgaccaa gaaggtgccg aataaaaaca tgccgccgat 490861 aaacacgtgg aaatttgtgt gtccggccgt aaacgccgtg attagggaaa tgatactgag 490921 cacgatcatg gcaatgccgg gcgcgactct catttttccc ttggatttat gggcagcaac 490981 agaacataaa atgccgataa caataggaac aatccacaaa taaaacagaa taaatactga 491041 catcatcaaa actccgattt ttcttctatc ataacaaatt tctgtcaaaa agggtatcaa 491101 tgagcttttg cggaaaaata aaaaccggct ttagaagccg gtttttttat cgaaacgtat 491161 ctacaattaa aaacacattc aaagcaacga tcaatacagc aatcagccaa gacaccactg 491221 tgatccattt ggcgttgatc agagatccca tgatccgttt attgcttgta aacataataa 491281 gcggaatgag ggcaaaggcg atcccgaagg acagcacgac ctggctcagt acgagagcgg 491341 tcgtcggatt aacacctgac gcgatgatca agatcggcgg aatgatcgtg ataaaacgcc 491401 gtacatacag cggaatgcgg tagttgataa atccttgcat aatcacgtcg cctgaaagtg 491461 tgccgacaga cgaactggat agaccggcaa cgagcagccc gatcccgaac aaagccgcag 491521 acatagggct gacaagatgt ccgaattgct gaaatgcgac gtcgagatcc tcaacaaaca 491581 ggccgttttt gaagaataat gcggcagcca caatcagcat acttgcatta atagcccctg 491641 caatcagcat cgctattaaa atatcaataa attcaaacct aaagattttt ttccgttctg 491701 catcagtttt gccaaccacc cgccgctgtg taagggcaga gtgtaaataa atggcgtgcg 491761 gcataacagt tgcgccaaga atacccgctg caagaagcac actgtcggtg ccatgaaacg 491821 ccgggacaaa aaggcccttc atcactgaca cggcatcagg ctttgcgaaa aaggtctgca 491881 acgcaaaggc gatcacgacc acaaacagca taccggcaat acctgcttca agtgagcgat 491941 aaccacggcg ctgaagctcc aatatcgcga aagaaccgat cgccgcaata atagacgctt 492001 caagcatcgg aatgccgaac agcaaataca gtcccagagc cgctccgata aattccgcca 492061 gatcagttgc gataatgacc aactcgccct gaatccataa tccgatcgag acaggcttcg 492121 ggaattcttc acgggcaacc tcaggcagat ttttgcctgt cgcaataccg agtttggcgg 492181 atagggattg aattaaaagc gccatgatat tggaaaataa gatcacccat aagagcatat 492241 atccgtattt agaacccgcc gaaatattcg ttgcgaagtt gccgggatca atataggcaa 492301 tggctgctat aaatgcaggg ccgagaaaag ggagcagccc tctgaatcct ctgattttcc 492361 cgtcaagcgc atcttggacg gctttggaac ggggagattg tgctgtgatg tccttgttca 492421 tcatgtctca cctgaattct gtttgttttt gccgtacaac aaagagtttc cttaaggcaa 492481 attattttat ctacatcata tgaccatccc ggtttcttgt caaccgaaaa tgttcaaaat 492541 acacttctga atttttccct gttatgtaac atgatatgta gggattcgtg ataaggtccc 492601 atataaaaag acatcgtttc atttcgaaac gatgcctcct gtatctaatg agtctaggct 492661 tccttccgca gcccgcggaa tataaggccc agcaagaaca cgaagatggc tgccccgatg 492721 atggccggga aaatagcaaa gccggcgagg ctcggtcccc atgtgccaag aagtccgtgc 492781 ccaatccaag cgccgatcag cccggcaatc atagagccga aaattcctcc cggcagccgg 492841 tttcctacaa tggcgctccc aattaatccg ataacaattg caacaactaa tgaaaccaaa 492901 aagctaagca tcatgatcac ctctcataaa tgatttacca atcaataacc gctcctgatc 492961 atttcgaaac acttgaaagc atattccttt atgatcctgt tttaatcttt ctctgcacac 493021 tgccgtcagc taaatgaaca atgacctcag tgcctttatg cgccgcgatt tcctttgccc 493081 gttcaatcgc ttctttcttt gtatccttga tttcagacac acgtttggcg ccctcggctt 493141 tgactgccca gcctttttta tgcttaataa catgctctgc tttattcatg agctcggggc 493201 cgctgccgct gcttggatca gcatcgcgtt ctgtctcatc atcatgcgtc aggaaatcat 493261 caatttcatc tgtagaggcg ttttccgccc attccttcgc tttgcttgtc gcaattggaa 493321 tcgcgcgccc ttcctcatag ccttcatcaa tcatcgcatt cgcaatgtct atcgcctttt 493381 ttctcaccgg cttctcaaga ttttttaatg aagcaggata atccttcatc gaccaaggca 493441 tgtctatcac tccttttcct tttataaaaa tggtacccgc aggtgaaaaa taaaaacgca 493501 tccgaaaaaa tgaaggtata ctatatagta gaaaaaacgg aagggaagtg cgggttgggt 493561 gccaacagaa cgaaaagaag acttacatca gcaattaaaa gagatagaga aatgggaaaa 493621 agatcagcaa aaagtctggt tttgggaaaa gctcagccgt ctcccgtttc aactcctgga 493681 caagctgaca ccagaattca tccagaaaaa gatcggcaag ctcttggatg aggtcggcag 493741 ctttgttcaa acaggcggac agtacctgac atctgaaaaa cagattatca ggatgtttca 493801 aaagaaactg ccggaggaga tctttgaatc gctggaggac atccggaaag cgcctcttcc 493861 tgtcatggat gaaattgcgg aaggaatggg caaaaacaga accaacgcag caaccgttca 493921 aggcgcgaca accggtgtgg gcggcgtgtt tacgctggcg gcagacattc cggcagtgct 493981 tggcttatca ctaaaaacat tacaggatat cgcagtcgca tacggctatg acccaaagga 494041 gaaaaaagaa cgagtcttca ttgtgaaatg cctgcagctt acgtcggctg atgttgtcgg 494101 caaaagatcg attttgcagg aattaaaaca ctacgatcaa gaccgtacat ataagaatgt 494161 cgcttctcaa atccaaggct ggcgagaagt cgttttgggc tatcgagaca cgtttggctg 494221 gaaaaaactt ttccagatag tgccggttgc cggaatggtt tttggcgccg ctgccaatcg 494281 ctcaacatta aacgacatta ccgagacagg catgatgctg tacaaaaaga ggcgcattct 494341 tgaacgactg aaagaaacag aacgagagat ggaatagcag aaagcagacg gacaccgcga 494401 tccgcctgct ttttttagtg gaaacatacc caatgtgttt tgtttgttta aaagaattgt 494461 gagcgggaat acaacaacca acaccaatta aaggaggaat tcaaaatggc agacaataac 494521 aaaatgagca gagaagaagc aggtagaaaa ggcggagaaa caacaagcaa gaaccatgac 494581 aaagaattct atcaagagat tggtcaaaaa ggcggagaag ccactagcaa aaaccatgac 494641 aaagaattct atcaggaaat cggcgaaaaa ggcggagaag ccactagcaa gaaccatgac 494701 aaagagttct atcaagaaat cggtgaaaaa ggcggagaag ccactagcga aaatcatgac 494761 aaagaattct atcaagaaat cggccgaaaa ggcggagagg caacaagcaa aaatcatgat 494821 aaagaattct accaagaaat tggctcaaaa ggcggaaacg cccgcaacaa cgactaatca 494881 aaagcataaa ggcagacaac ctgtaaataa aaaagcgatc cggcacatca gctggatcgc 494941 ttttttttgg aatcttctca atttatgccg ctattgagat acaataagtg aaaaaggggt 495001 tttcgctaat gtccaagatg caaaacttgc tcgccatcgc aaatgaagtc aaagaaaagc 495061 acgccaattt ttcaatctca gaggtcaacg accactgcgt gcgccttgcg gtgtttacgg 495121 gagaatatga ctggcaccat caccctgact cagacgaatt gtttattgtt cttgaagggg 495181 agctgctgat cgattttaag gacaaagaaa ccgcggtgct caaagcaaat gacagcctgc 495241 tgatccctaa aggcacggtt caccgcacac gctcttacgt cagaacggta aatctctgtg 495301 tggagcataa acaagccgaa accgtcatca tagaggagca gccatgctaa tcaaaaagat 495361 gatatgtgaa gtagatgctg caaacgctga agcatttgca aaagcgcagt cacagtggga 495421 agcgttatcg catataagcg gctttatcaa acaggccggc ggctggcgaa aaacgataga 495481 cgagccgctc accgcagaaa tcatcagtgt atgggaaaac agagaagcct atgatcattt 495541 tatggagaac gaacatgaca gcatatacga ggaaaacgat cagaaggctg taattctttc 495601 gatagaggtg acggtgtacg aagaggataa accgttcgtt cacgatctgt tacataaccc 495661 cgatatccgg tacgaaccaa actggacggt tctgaaggca taatcaaagc ccaaaacatc 495721 atgttttggg cttgtctctt tactcgcgtc ccggaagtgt attatgaaca aaaggcggtg 495781 ctggttttaa ctccggtttt tctccaaacg tttttgcttc tttcacatat tcaaaggctt 495841 ctccgtccgg cgctttttca ttcagccagt tttgctcggc gcttacttcg ccttcagaga 495901 aattgataag ctgatgtgag aactcttgtt tttcgagcgc tttcgggaat gtacccggca 495961 caaccggacc ttcctgtgct tctaattctt taatggcggc gagccattgg ttctggtgca 496021 tcgtgtcacg cgccagcagg aagctgagca tatctttgac gcctttgtca tccgtcattt 496081 caaacaggcg tgcgacctgc agacggccct gagattccgc attcaggttg gcgcggaagt 496141 ctgccagcag gtttccgctt gctacgatat aaccgccgct ccaaggtacg cctgtactgc 496201 tttccggcat ggcgccaagt cctgatacaa tcgcatggtg agggttcatg ccgcctagga 496261 tggagccgat gaccggatct tcagcagctt tttcctgctg atcaagaggg gcatcctcaa 496321 gaagtctggc aatcatcgtt gcgatcattt caacatgccc gagctcctca gttgccgtat 496381 ccatcagcaa gtccttgtat ttttcatttc ctcttgtgtt ccagccttga aataagtact 496441 gcatggcaac tgaaatttct ccgaattgcc cgcctaaaat ttcttgcatt tttttagcga 496501 ataatggatc tggacgatct ggtttagcag gatgctgcag catttttgtg tgcttaaaca 496561 tgtacccatc tcctttttcg tttatctctt tttatatttc cgatcgatag aaagataaac 496621 gaaaaacagc gtatcgagat gggaactatg aatcttttcg cagctccaac agttcccgga 496681 tcagctcccg gccaaagatg ggctcatact gccggtaaac agggtcaaga cgcttcatcc 496741 attcttgttt ctctttatct gacagctcat aaatatgtat agcagaattc tttttgattt 496801 cttccagctg ctccttgttc atttgttcgg catacgtttc attccactcc gttgtctcct 496861 tcatcgcttc agtcaaaatg cgtcttgttt ctggtgtttg cgccttccag aagtgttcat 496921 cagtcatgac agcgtagccg agataaccgt ggctgcttat tgtcaaatag tcctgaacat 496981 tataaaattt tttagaatag atgtttgaaa ttgtattttc ttcgccatcg actacattgt 497041 tttctaacag ctgaaaggta gaattgaagg attcctgatg aggtgttgcg ccaagcagct 497101 tgaactgatc ctcaatcaca tcgctttgca taatgcgcag atcctgccct tttaagtcat 497161 ccggtgtttt gaccggccct tgatttgttg tgatttgctt aaagccgttc gtccaatagg 497221 ccaatccttt caattggttt ttctttagag aatcaaacag ctgtgtgccg atgcttccgt 497281 tcagcccttt tttgacggcg ttgtaatctg taaatgcata cggcagatcc agcactcccc 497341 attcaggcga gagcatgccg agcttcgatg tggagggggc gataaattga acatcgccgt 497401 tttgcaatgc ttcaatttct tcaatgtccg agtacaggct tccattcgga aatacttcta 497461 tttttatttt tccgcctgat ttttcgttca ccagatcagc gaatttattg gcggccagcc 497521 cttttggcgt attttcagca accacgtggc tgaatttaaa cacgatttga tcctgcaggc 497581 cttcctggtc gtcatcataa acaatctttt tattgccggt atgatcatgg aatccgataa 497641 ataaagcggt tgcaattcca gcgatcatca gtgcgagaca tgcaagcaaa ctcttcatga 497701 aaagccctcc cctatgttaa ggataatggg ggctatgaca ttcgtaaaga cctgaaagga 497761 gaagctgatg aacaaaaaga agctctcaat ccgttggaaa atcacgatct tatcctatat 497821 actcgtcatt ttctcctttt tgatcggcgg cattgtgctc atcggcaaca ttcagcatac 497881 agaggagcgg gagctgaaaa agcggctgat gaatacggcc cggacggtgt cagagatgac 497941 agaagtgaaa gaagccttgg cgcgaaaaaa acaaacagaa gcggttcgcc atgcggttga 498001 agaaatcagg atgattaatg aagcagacta tattgtcgtc atggatatga atcacatccg 498061 atatacgcat cctgtcagca caagcattgg caagaaatca gaaggtgcag acgaggaggc 498121 agcttttgcg gagcacattt atttctctga agcaaagggc gagatcggca cggcggttcg 498181 cgctttttat ccggtaaagg atcaagacct gaaccaaata ggcgtggtgc ttgtcggaaa 498241 aacgctgccg gggatcgctg acatcctgct tcatttaaag cgtgatatcg ccttcatcgt 498301 tgtgctgaca ctcggctttg gccttgctgg ttcctttttg ctggcccgcc atatcaaaaa 498361 acaaatgttt cagcttgaac cccatgagat tgtccgaatg tatgaagaac ggacagcgac 498421 gtttcactcg atgaatgaag gggtgatcgc tattgacaat cgtctcgtca ttacgatctt 498481 caatgaaaaa gcgaaacaga tctttgaagt gcagggggat ctaatcggca aggtgatttg 498541 ggaggttctc aaggattcgc gcctgcccga aatcgtggag cggaacaaag cggtttataa 498601 tgaagaaatt cgtgtcagcg gtaaggtgat catgagcagc agaattccga tcgtcatgaa 498661 gaaaaaagtg atcggcgccg ttgcgatttt tcaggacaga acggaagcgg ccaagatggc 498721 agaggaattg actggtgtca gaaactttgt ggaggcgctc cgtgtccaaa accatgagca 498781 tatgaataag ctgcacacga tcgccggtct catccagctg gggaaatctg aaaaagcctt 498841 gcagcttgca ttccaggcgt caactgagca ggaaaatgtg actgaatttc tgcaccgctc 498901 gattcaaaat gacgctgcgg caggccttct attaagtaaa atcagaaggg gaagagagct 498961 cggcattgct gttcatatag atgaaaacag cagtcttcag caatttcccg agcatgttga 499021 tcagcatgat attgtcgtgc ttttggggaa tctgattgaa aatgccttcg gctcatttga 499081 aaccgttcaa tctgaagaca aacgaattga cattagtatc gaacaaacag atgatatcct 499141 tgctatttta atagaagata acggctgcgg aattgaaccg acacatatgc ctcgccttta 499201 tgacaaaggt tttacggtca ataaaactgg cggcacaggc tatggcctgt atctagtgaa 499261 acaaatcata gacaaaggat cgggcacgat agaagttgat tcacatgcgg ggcaggggac 499321 atctttttct atcgtttttc caatgaaggg ggaggaagca cagcatggct cgtaaagaat 499381 ggaaggttct gctcattgaa gacgatccga tggttcaaga ggtcaataag gatttcatta 499441 caactgttaa aggcgttact gtctgtgcaa cggcaggaaa cggagaggaa ggcatgaagc 499501 tgattaaaga agaacagcca gatctcgtca ttctcgatgt gtacatgccg aaaaaagacg 499561 gcatcaagac cttgcaggag atcagaaagc aaaagcttga agtggatgtc attgtcgtct 499621 ccgctgcaaa agacaaggaa acgatctcac tcatgctgca aaacggggcg gttgactata 499681 tcttaaagcc gtttaagctt gagcgaatga gacaggcact cgaaaagtac aagcaatata 499741 aacaaaaaat cgaagcgaat gatacgctgt cccaggaaca gctcgatgcg atcctgaata 499801 ttccgcagca ggccgtacag gatctgccga aagggttgaa tcacttcacg atgaatgaag 499861 tcactgcttt tttgaaacag caaaccgcat ccctttctgc tgaagaggtt gccaaggcgc 499921 tcggcatcgc cagagtgaca gccagacgat atcttgatta cttagaaaaa accgggatca 499981 tcaaattgga cgttcaatac ggcggagtcg gccggccggt caaccgctac gtgttaaaag 500041 gataaacctg agaccaaaaa gaccaaaatg tccgttatga tcataaactt ccccagactg 500101 tatgaaaacg ctatcattct agtaagaaag acacaaaagg cgaataggac agggggatga 500161 aggatatgaa actgtttaaa aatttaacag ttcaggtcat aaccgcggtc atcatcgggg 500221 tcattgtcgg gctggtctgg ccggatgtcg gcaaagaaat gaaaccgctt ggtgatacat 500281 ttatcaacgc tgttaaaatg gtgatcgcac caatcatttt cttcacaatc gttctcggga 500341 ttgcaaaaat gggcgatatg aagaaggttg gaaaagtagg gggaaaagcg tttatctatt 500401 tcgaggttgt caccaccctc gcactcatta tcggtttatt tgtcgtcaat attatgaagc 500461 cgggtgcggg tcttgattac agcaagcttg aaaaaggaga tgtatcacaa tacacgcaaa 500521 atggcggtca gggaatcgac tggattgaat ttattacaca cattgttccg tccaacatgg 500581 ttgatgcctt cgcaaaaggg gacattttgc aggtcttatt cttttctatt cttttcggag 500641 tgggtcttgc ggcattaggc gaaaaaggaa aaagcgtcat tgatttcttc gacaaggttt 500701 ctcacgtttt tttcaaaatt atcggctaca ttatgcgtgc cgcgccaatc ggggcattcg 500761 gggcgatggc gtatacaatc ggacacttcg ggctcgattc catcaaaccg ctggcaagct 500821 taatgatgtc tgtttatatt acgatgttcc tgttcgtatt tgttgcttta aatatcatct 500881 gcaagcttta cggattcagc ctgtggaatt accttcgctt cattaaggat gagcttttga 500941 tcgtgcttgg cacaagctct tccgaatcgg tgcttccgcg tatgatggat aaaatggagc 501001 gctacggctg ttccaaatcc gttgtcgggc ttgttattcc gacgggctat tcgtttaacc 501061 tcgacggcac atccatctat ttatcaatgg cgactgtctt tttggcacag gtgtttggag 501121 tagacctcag catcggccag caaattacga ttatcctcgt tctgatgctg acatcgaagg 501181 gagcggcagg tgtgacggga agcggattta tcgtccttgc ctcaacgctg tcagcgctgc 501241 aggtcattcc gctggagggg cttgcactcc tgctcggggt cgaccgtttc atgagtgaag 501301 gaagagccat tgtgaacctg atcggaaacg gaatcgccac gatcattgtt gccaaaagcg 501361 aaaatgaatt tgatgaagca aaaagcatag aggctgttga aggcatgaaa aaaatgaaaa 501421 cagcagtctg aaaaaagaac ggcccatcca tgggccgttt ttttaattgt ttaagaatta 501481 ttaaggtaag gacagagacc tcagcatttt tttgttatat aatttacaaa tggatactat 501541 attgaatgaa ggacgtttgt cctaacagga gtgtataaat ggccgcttta gttaaatttt 501601 ttcagcaccc gggagtaagg cgtttctcca tctttgtcgt gttaactggt gtgttatatc 501661 tatttaagag catgatcaac ttaatattgc ttaccttcat tttcacattt ctaatggatc 501721 gtttggagct tgtcgtgcgg cagtttgtaa gccagttctt ccgcgtgagc cagcgggttg 501781 tcattacgtt tctttacatg ttgctggctg tgctgcttac agtcgggggc tttgtgtttt 501841 atccggtcgt cgcggcgcag atccagcagc tggtaaagca gattaaacat attgcgtatc 501901 atcctgacag catccctttc tttgatgaga tcaccagtgt cttcggagat attaacatca 501961 gttcatatgt caaagagggc ttcaatgtag tgtatacgta tctggccgat atcagcacat 502021 tcggcttgca ggtcgtgatg gcgctcattc ttagcatgtt tttcttattt gagaaaaaac 502081 ggctttctga attcatggcg aaatttaaaa cgagcaaact tagggtcttt tatgaggaga 502141 ttgctttttt cggaagcaaa tttgcaagaa cgttcggcaa ggtgctcgag gctcaattta 502201 tcattgcgct cgtcaactgt attctgacgt ttatcgcgct ttggattatg cattttccgc 502261 agctgtttgg gctttcgatt atggtgttct tccttggatt gatccctgta gcaggcgtcg 502321 tcatttccct gattccgctc agcattatcg cctacagcac tggcggtgga atgtatgtgc 502381 tctacattgt ccttgtcata ttcgccattc atgcgatcga aacctatttc ttaaatccga 502441 agctgatgtc ggcgaaaaca gagctgccaa tctttttcac cttcacagta ctcattttct 502501 ctgaacactt cttcggcatt tggggtttaa ttatcgggat tccgatcttt gtgtttctcc 502561 ttgatattct ggatgtcacc aacaaggaag ataggtctaa aggaccccga gagaatagcg 502621 ataaaaagta gtttaaaatc gaataatgag tgtgcctcga tctgccggcc tgcctgttca 502681 gggcatggaa ttaagactcg gaatcggagc ttggcattgc cttgcacagt ggtgaacaca 502741 acaggtgaca atgcttgtca tcagtacgga aactgaaaag aacaaacagt cggagcaaac 502801 gctcatcatc ggtttaacca aacatttgga agcaacaaat gctataatac aaacagtgcc 502861 taatgttggg cactgtttat tttttgtcga aaaaggagga aggctttatg gctgagccga 502921 ttttacatat tgaaggcctc gataaaaaaa ttgggtctaa acagatttta aaacagatca 502981 gcatggacgt catggagggt gaaatcatcg gccttctcgg tccgaatggt tccggaaaaa 503041 caacactcat ccgtatcatc gtcgggctgt tgaaacaaaa cagcggaagc gtgacaatca 503101 gcggattcca gcatgataca gagtttgaaa aagcgatgga agcggttgga gcgattgttg 503161 agaaccctga gttctatccg tacctgacag gctgggaaaa cctcaagcac tttgcgaata 503221 tgcacaaaaa aatagcggat gaacggcttg atgaagtggt ggaacgtgtc gggctgacgt 503281 cagcgattca tgataaggtg aaaacctatt cccttgggat gcgccagcgt ctgggaatcg 503341 cccaggcaat tcttcaccgg ccgaagcttc tcattctaga tgaaccgaca aacggcctcg 503401 atcctgcggg gatgaaggat tttcgggatc atattaagga actcgcagaa atggaaggaa 503461 cagctgtcct gttcgccact catttattgc gcgaggttga agacttgtgc gaccgtgtca 503521 tcatcattca aaaaggtgag atcaaagcgg aagtcagctt acaaggaacc gatcaaacca 503581 cagaaaaagc gattatagaa gtgcagccgc aagaaaaagc gctcaattgg ctgacaggca 503641 atcaatatca agctgagagc caagacggga cgattgtagt tgaggtggca aaagaaaaca 503701 taccggagct gaaccgatca cttgtcggac aagatctgaa tgtattttcc attacgcctt 503761 acacgcagtc actggaagac gaatttataa aagcgacaac agctcatcaa gaggagggag 503821 aagagcttgt ctaaattaat ttggaatgaa catatgaaac tttttaatcg gaaggtcact 503881 ttggtttctc ttatcctgat ggctgtcttt caattcttca tggcattgat cattaaacgg 503941 attgtcatca gtgccggaac agatgaaaac ttcatcggct atttatcgta tacaccgagc 504001 ctgaacattt tgctgcaggc tttaacgatc gtaattgcag caacaattgt ttcgatggaa 504061 tttgataaaa agacgatcaa atttttgctc attcgtccgg ttaaacgcca aaaggtcttt 504121 tggtcaaaat taatcacagt cgtgatggtc agcttctatt tgtatttggc atactacatt 504181 ctggcattat tattcggtct cttgtttttt ggcacatcgg tgactgcgga atcaaagaca 504241 ttgctggtca acaccttggc gctgatcggg tcaaactggc ttgaagctgt aatgatggga 504301 ttattcgggc tgctttgttc ttcgctgttc cgcaatagcg cggtagcagt tgttgtttct 504361 tttgtcgttt tatacggagc gagtacactt gttcagctca tgaagttgtt tgaaaacaag 504421 tggggcagct ttttgctttt tgcgaacact gactttacgc aatacagaag cggagagaca 504481 gcgttgtttt caggcatgac gccattgttt tcaattggaa ttctcatcat acatgccata 504541 ttcttcatcg ttgttggctg gtggtgcttc tgtaaacggg atgttcgggt ctaaaggcaa 504601 ggaatgacat ttttgtgaaa aagctcacgt aaatcaatat catttgatat tttggtttat 504661 actaaaggta ctgacggagg tgtctcgatt gaggaacttt attaccgctt taccgatcgt 504721 attgctgctt ggattctcat ttgtgtcatt catgtttcag tttgaacatc ttgtttattt 504781 caggctcgcg cttgggttgt tttctctcgt gggactgtac atgatatata aaatgaagac 504841 gggcatccgc tattttatca tctatctgta tgccagctgg attgtgttgg ccgcagtgac 504901 cgcttttgaa gagccgattt tctcaagctt tttctttggc ggcctggtga tgacgatggg 504961 ttacctgaca tatatgctga tttatctcgg catgaaacaa gaccgggatg caaatcctgt 505021 gtaatcgcgc tgttcccttg gggaacggcg tgtttttcta tactgggcaa aaggttaaca 505081 gttgcggaaa aatggcagga aatctataat acatattaaa tttatcggaa ttaaaactgg 505141 ggggctgccg gatgtcatta tttatacaaa acgatcaaca gcggcaatgg atggagaaaa 505201 tcggacggat tgcggatgaa tttcagcaaa cagctgctga agatgacgaa cagggacgtt 505261 ttcctgcaga gaaaatacaa aaactgcgtg atgctgggta tacagcatta acattgccgg 505321 catctcatgg cggagggggc atttctgttt acgatatgct cttgtttcaa gaacggcttg 505381 cacggggaga tgctccgacg gctcttagca tcggctggca tttgagcgtg atcggggagc 505441 ttggagaagg caacagctgg gatgaagacg tatttgcatt tgttgccaag gaagtccaaa 505501 acggagccgt cattaacagg gcggcgactg aagcgaaaac cggaagcccg acaagaggag 505561 ggcgtcccgg tacacacgcc gtcaaaaagg atggcaaatg ggcagtgaac gggagaaaaa 505621 cctttacgac gatgtcacaa gctctggatt attttttagt aaccgcatgg attgaggaca 505681 aacaaacaac aggcgtgttt ctcattcata aagatgatcc cggcttgtcg attgaagaaa 505741 cgtgggatat gatggcgatg cgggcgactg ggagccatga ccttgtactg aacgaagtaa 505801 tgcttgatga gaataagctg gtggaactgc ttcaagggcc tcgtggagct aagccgaatg 505861 gctggctgct tcacattcct gcgatttatc ttggtgtggc tcaagctgct cgtgactatg 505921 cagtgcaatt tgcatctgag tattctccaa acagcttgaa tggaccgatc aagaatgtcc 505981 cggccgtaca gcaaagaaca ggcgaaatgg agcttgaact gctcaatgcc agacactttc 506041 ttttccatat cgctcaattg tatgacgatc cggtgcggcg tccacacttg accagcgagc 506101 tcggtgcggc gaaacatatc gtcacaaacg ctgcgctgtc tgttgttgat aaagcgatga 506161 gaattgtcgg ggccaaaagc ctggaacgaa ccaacccgct tcagcgctat taccgtgatg 506221 tgcgcgccgg tcttcacaac ccgccgatgg atgacgccgt gatacacaag ctggcagctg 506281 aagcgtttga gtcataaaaa aaagagcctt accggctctt tttatgtatt gttttgctct 506341 tgcagatttt tttgatgctt gcggtcgatc ctgtcataaa taacgttcat cagctttgga 506401 ttgcccataa tcgcctcttt gttttcctgg atcagctgtt ggtaagtttt cactttacgc 506461 ttcggcatgc tccggcgccc tcctgacatg tttgtattca ctttctaact ccgtcagcga 506521 caattcatac agatgacgct ttgacttttt gtatatacca ttctgtatta acagatgaat 506581 gagctgtttt tttctgattt ctgcagactg aggtgtcatt gtgtcaccaa cctccaatca 506641 aacgatattg ataatcatta tcaattaact tcagtataca atgtccgcaa tagcctgtaa 506701 agatgaaaag agtcctattc ttggccaatt tacaaacatt caacaaatcg acaaaaagtt 506761 tcccgggcaa taatttgctg tcgaaatatt ccgcttcatt gaacgcaccc tgctattttt 506821 catgttttga accatactat gtaatagaat ggaggctggt attcaatgga gcggacagaa 506881 aatctgaaaa agggagaaaa aggggcgctc ctcaatattt ttgcatatgt catccttgct 506941 gttgtaaagc tagttatcgg gattctatat cattctgaag cgctgagagc agacgggtta 507001 aataatggaa cagatattgt tgcgtcagta gcagtgctga taggattgcg gatttctcaa 507061 agaccggctg acagcgatca tccatacggc cattatcggg ctgaaacaat ttcgtctctt 507121 gttgcgtctt ttattatgat ggcagtcggc attgaagtgt taatcggcgg aggaaaagcg 507181 attgcgggcg gcacaacgga aacgccaaat cttatcgcgg catggacggc gttaggcagt 507241 gctgtgttta tgtatggcat ctatttatat aacaaaaggc tggcagcgtc cattaaaagc 507301 tctgccctga tggcagcggc aaaggacagc aggtcagacg cttttgtaag tgccggcgcg 507361 tttatcggtg ttttttcgtc ccagctgaag ctgccgtggg ttgatccggt aacggctttt 507421 atcatcggca tcatcatttg caaaactgcg tgggatatct ttaaagacgc ttcacattcc 507481 ttaacagacg gcttccattt aaaagatctt gagccttaca aacagaccgt cggcaggatc 507541 gaaaatgtgc atcgcctaaa ggatgtgaaa gcgaggtatt taggcagtac agttcatatc 507601 gagatggtga ttacggttga tccgaagctt acagtagaag aaggccatgg agtggcggat 507661 gaagtagaag acaaaataaa acatgaacac gatgtcactc atgttcatgt tcatgtagag 507721 cctgacgaca taaaataagg ctgtttaacg aattagctta tatgttcaga taaaaattca 507781 gtcacttctt caggcgtttt ggcattggcg ctgtgaaggt gagctgtttt ttcaccgttc 507841 ttgaaaataa gcaggctggg aatgcccatt acttggtatt tttcagccag gtcaggaagc 507901 tcgtccttat tcagctcata ccagtcgttt tggttgtatt cttccaaaat atcgccgatg 507961 aacatattca tgcgtgtgca gtctgggcac caatcagcat aaaactttac aatgatttct 508021 ttatcagatt gaatcagttc attaaattgt tcgtttgttg tgattttttt catatgtcac 508081 atctcctttt caatgccatt ttaatataaa ataaaaagga attacataca aatgcattca 508141 acatcagcat gcccaaaaat aattagatca ttttccggtg aaaatgataa gatagtaaag 508201 atgaattgta gtggggggag tatccattga aaacaagtct aggattagtg tacggaggaa 508261 agtcggcaga acataatgtt tccctgcaga cagctctggc tgtaatcaaa gcgctaaata 508321 ctgagaagtt tgatatacat ccgatttata taacagaaaa aggcgaatgg gttagaggcg 508381 cccgtttaac tgaacctgtt tcaaacgtga aaatgcttca atttgagcaa ggaggcagtg 508441 ctttttctcc agctgccctg aaccaggaga tgtttccgca ggaagcgtca cagcaaaatg 508501 aagccatcga cgtcgtattc ccgctcctcc acggaccgaa cggagaagac ggtacgatcc 508561 agggaatgct cgagctgttg aacattcctt atgtcggcaa cggagtgctt gcttcctcag 508621 ctggcatgga taaagttgtc atgaaacatt tatttgcgca ggttggcctt gctcaggcta 508681 aatacgcagc tttccttaag aaagactgga ctcgttctcc gaaagaaagc tgtgaggagg 508741 ttgaacagga attaggctac ccttgcttcg taaaaccggc gaacctcggc tcaagtgtcg 508801 gaatcagcaa atgccgaaac cgtgaagaac tgcaaaaagc gtttgagctt gctttccaat 508861 atgaccgcaa agtcgtcgtt gaagaaggaa ttaacggccg cgagatcgaa atcggcgttc 508921 ttggaaatga tgatcctaaa tgctctgttg tgggagaaat cgcaccgaag acagatttct 508981 acgattacaa agcgaaatat gaggatggag atactgatct gatgattccg gcgattgtga 509041 ctgatgagga atacgcaaca atcagtgata tggcgatcaa agcgtttaaa gcgatcgacg 509101 gttcaggact cgtcagagcg gactttttcc tgacagctga cggcgaagtt ctgatcaatg 509161 aagtcaacac aatgcctggc tttacacctt tcagcatgtt cccgttgctc tggaaagaag 509221 ccggagtgga atatgctgac ctgattgaac agcttgtgga gcttgcaaaa gaacgccacg 509281 ctgaaaaaca attgattaag catacattct aatgaagaag gacactgccg gtaaaagggc 509341 agtgtttttt cccgtatata caaaagaaag agagggacct tacttgatta agcgaacagt 509401 aaaaaacatt gccgaaatgg ttaaaggcac actagcaaat ccgcaatatg aacaaacagt 509461 cattcatgga gtggcaaccg atacaagaaa actggaacaa catcagctct ttattccgct 509521 gaaaggggaa cgttttgacg gccactcttt tgtggagcag gcctttgaag ctggtgtagc 509581 ggctgttctt tgggatcggt cagtaccaaa tccgcccgag aatcacgccg tcattttagt 509641 ggacgatacc cttactgcac ttcagcagct tgcaaaagct tatttgcagg agcttggcac 509701 gcgtgtcatc ggagtaaccg gaagcaatgg caaaacgaca acaaaagata tgattcacgc 509761 cgtattgggg acccagtacc gtgtccacaa aactggagga aacttcaata atcatatcgg 509821 tttgccgctg acggttttag cgatgcctga aaatacggag atcgccgtat tggagatggg 509881 aatgagcgcc aaaggagaaa ttgacctctt gagccgactg gcaaacccgg atgcggcagt 509941 gattacgaat atcggcgaat cgcatatgca agacctcggc tctagagagg gcatcgcgga 510001 ggcgaagctt gaaatcataa acgggcttaa agaagacgga gtgctgattt atatcgggga 510061 cgaaccgctt cttcaaaatg catacagctg ccagacgaaa acgtacggta cgggaacgca 510121 taatgattat cagcttcagg atgtcagcca gagtgaggaa ggaacccatt ttacaatcaa 510181 agggatagaa aacacgtttt ttattccaat actcggcaag cacaatgtga tgaacgccat 510241 ggctgcaatt gctgcagggg cttattttgg catcgcgcct gaggatgcgg caaaaggact 510301 gagcggccta aaggtaaccg ggatgaggct tgaactcatc aaaacagaca gcggcctttc 510361 gataatcaat gacgcttata atgcgagccc gacttccatg aaagctgcaa ttcaattgac 510421 agaaagcctt gaaggctacg gcaaaaaaat gctcgtgctc ggtgatatgc ttgaactcgg 510481 cgatcttgaa gaaacgttcc ataaagagtg cggcgctgtg atcagccctg ataaaattga 510541 ccgcgtcttt acgtacggaa aactgggagc ttttatcgcg gaaggcgccc tgaaacactt 510601 tgagaaagac cgcgtcagcc attacactga gaaaaaagat ctccttcaag ctgtgaagga 510661 aaacgcatca aaaggcgatt tgattttatt caaagcgtcc agaggtatga agcttgaaga 510721 aatcgttaaa gatttaatag agagcccgct ttcataagaa aatattttgc gaaaaaacgc 510781 atattgcatc ataaaataac ctgatatgca aacactaatg tatgccggcc gaaaattatg 510841 tatatctggc cggctgcggc tatgatacaa tatatatagg ttatttcgcg atacgaacat 510901 attcgtccgg acttttcatc gtgacccgaa gttctccgct ggattcttgg gagcggatgg 510961 agcagcagcc ggcatattcg agatgccgat ctgcttctca tcttattgaa aaacaaatag 511021 tgtaatggta agataaaact taaagtaatt cgggctttgt atacggatgg atcctgtcct 511081 tcttgtctaa agggcagttt tataagtggt aaatcacgac attactgaaa cagcaattag 511141 aaggagtttg aataatttga ctataacgtt tcaagatttt aatttaagtt ctgatctcat 511201 gaaagcaatt aatcgtatgg gatttgaaga agcaacaccg attcaggcac aaacgatacc 511261 gctcggactt tcaaataaag acgtcattgg acaagcgcaa acaggtacag gtaaaacagc 511321 tgcgtttggt ataccccttg ttgaaaaaat taaccccgag tctcctaata ttcaagcaat 511381 cgtaatcgcg ccaacccgtg aattagccat tcaagtatct gaagaattgt ataaaatcgg 511441 acaagataaa cgtgcgaagg ttcttcctat ttacggcgga caggatattg gacggcaaat 511501 ccgggcgtta aagaagaatc cgaatattat tgtcggaaca cctggacgtc ttcttgacca 511561 catcaaccgc cgcaccattc gtttaaacaa tgtaaatacc gttgtaatgg atgaagcgga 511621 tgaaatgctg aacatgggat tcattgacga tattgaatct atcctttcaa acgtgccaag 511681 cgagcatcag acacttctgt tctctgccac aatgcctgcg ccgatcaaac gcattgcaga 511741 gcgcttcatg actgagccgg aacacgtaaa agtaaaagcg aaagaaatga cggtttctaa 511801 cattcagcag ttctatttgg aagtgcaaga acgtaaaaaa ttcgatacac tgactcgcct 511861 tcttgatatt cagtctcctg agcttgcgat cgtattcgga cgtacaaaac gccgtgtcga 511921 tgagctggct gaagctctga accttcgcgg atatgcagct gaaggtattc acggtgactt 511981 aacgcaggcg aaacgtatgg ttgcgcttcg taaatttaaa gaaggcgcaa tcgaagttct 512041 agtcgcaact gatgttgccg ctcgcggact tgatatctca ggtgttacac acgtatacaa 512101 cttcgacgtg cctcaagatc ctgaaagcta cgttcaccgt atcggaagaa cgggccgtgc 512161 aggaaaaaca ggtatggcga tgacgttcat tacaccgcgt gagaaaagca tgcttcgcgc 512221 aattgaacaa acaacaaaac gcaaaatgga ccgcatgaag gagcctacac ttgatgaagc 512281 gttagaaggt cagcaacagg ttactgttga acgtcttcgc acaacaatca gtgaaaacaa 512341 cctgaacttc tacatgacag cggcagctga gctgcttgaa gatcatgatg cagtaacagt 512401 ggttgcggcg gctatcaaaa tggctacaaa agagccagac gacacaccgg ttcgcttaac 512461 agacgaagcg ccgatggtca gcaaacgcta caagaaccag cgctcttcta aacgcagaga 512521 cggtcaaggc ggcggctacc gcggcggaaa agggaaaagc aacaaccgtt cttcctatga 512581 caaaaagcgt tcaaacgatc gccgttcttc aggtgacaga cgccagaaaa aatcttacta 512641 atttgatcga ttcagagccc aaaacatgat gttttgggct tttttatgtt cgtgatttgt 512701 tattcagcaa actttcagct gacggaagcc atttttctct gtatgcttaa gaatgaaacc 512761 tttctgtaaa agagacgtat aaataacgac gaaaaaaagg gaggtaggta tttttgagag 512821 agcagccaaa aaaccaaatc agtccagacg gattaaaggt ttggcgactt caagagatca 512881 tcatatccgc tgtttgcttg cttattgtca ttgcagttgc agtgttaagc tattattttc 512941 attggccgta ctggatcagc ggcgtgctcg gcgctgtttg gctgctggga tcgattgtga 513001 cggtctttat cattccgaag gtccgtcata aggtgtggcg atatgaagtc catgaacatg 513061 aaatagatat tcagtcaggt atttttgtgg tgacacgtgt gattgttccg atggtcagag 513121 ttcagcacgt cgatacgtca caagggccat tattaaaaaa atacaacctg gcaacggtga 513181 aaatttccac agccgcgacc gttcattcga tccccgcttt agagatggag gaagcggatc 513241 ggctaagaga ctccatttcc cgtctggcga gggtgactga cgatgatgtc tgaaccgaaa 513301 cgcctgcacc cggtggcagt cattttgaat ttatgccata ccattattca aacgataaaa 513361 aatatcattc tgccattctt ttttgtgtat attgtcaatt caaaccatac tgtccgtttt 513421 tacggagcca ttgcgctcgg tgtgctgttc atctggcttg tagcggcaag cattatcaaa 513481 tggagaaggt ttacctatcg aattgaagat gatgaattta gaattgaaga aggcttattt 513541 gttacgaaaa aacgatacat atcgattgat cggattcaaa caatgaatac gagcgcgggc 513601 cttgtccagc aaatctttaa gcttgtgaag ctgcaaattg aaacagcagg cggaggcaag 513661 gaggcagaag ccgttctttc tgctatttct gttgaagaag cggaacgcat caaagaagct 513721 gtctttaaga aaaaagcgca aagacgagaa aatgaacttg atgaagaacg gcttgaagct 513781 gaagaggagt tggatccgtc cgttgaggtg caagagcact atcgcatgaa cgcgaaagaa 513841 ttgctcatgg ccgcttctac ctccggcgga atcggagtca ttatctccgc tgtatttgca 513901 cttatttccc agcttgatga agtgctgccg atggattggt tattcgataa attttccttc 513961 cttcagcacg ccagcatcgg tatttatgcg gtactcattt ttatcggttt atttatcgcc 514021 tggattttca gcatcgcggg catgatgttt agatacgcga actttcaaat cataaaaaaa 514081 gagcaggaac tggtgatttc aaggggaatt attgaaaaac atcaagtcac gattccgctg 514141 cgaaaaatac aagccattaa aatcaaagaa aatatcattc gccagctttt cggctttgta 514201 acggtgtcca tcgtcagcgc aggaggcggc gaccgggaaa aagaagaagg cgctttgacc 514261 attctctttc caatgattca taaaaaaaag cttccgcaca tgctccgaac atttacgccg 514321 gaatacacgc tggaagaaaa ctgccgccgc ctgccgcggc gcgcgttgaa acgctatttg 514381 ttccgttctg tcattttttc actctttttg atcatcccgt tatgtatctt ctttcagcca 514441 tggggctatc tgtcagtgat cctgctgccg atagaattgc tcttcggcta tctcgcgtat 514501 aaagaggctg catggacgat caacggggac cgtcttcagc tgacgtctag atttataggc 514561 agaacaaccg ccattgtact gaaaaaacga atgcaggtct gcaagttcag ccaatcctat 514621 ttccaaaaga aaggccgctt gtataccatt tctacttcgg tgaaatcatc gagccatatg 514681 gaagagttaa cggtgaggga cgtaggtgaa gaggatgcag ccttcatttt aaagtggtac 514741 tcatatgaaa aagcggacgg ttaataccgc cgctccagcg tgtcggcaaa ccctcgcatt 514801 cgttgtcagg actgcgcttc ggtgctcaat gcgaagtgga tcaacggcta aattctcagg 514861 cgtcctgcct aaacgccgtc gtcatcacat cctgtgaaag tccgctccta tgctcgtcct 514921 tcctagactt catgggtttt caatcacgct gaaaagatga caaaatccta aaatgaaaac 514981 cattttagga ttttgtcaac aatctgaagc ggcggttaat accgccgctc ttttttttgc 515041 acgcataaaa acgaaagaag aaacccgccg catagtccaa acaaatgggc catcatgtta 515101 atattggagt tgataaacga catgagaacg gcaaatgcga gcagtgtgat gatcattttg 515161 gaatgctcct gcccaattaa ctcattgcga aaaagaacca taaacaggta tacgccaaat 515221 agcccgaaaa tggcgcctga agccccgaca tgcacgtaat caagcggctc tgtaacataa 515281 gtgccgatat tgccgatgat gccggagccg gcgtatacaa gaaggaaacg cgcttttccc 515341 agcatgcgtt ccaaagccgg ggcaaataaa aagatggaca tggaattaaa cagcagatgt 515401 gtgaaaccgg cgtgcagcaa aatcggtgtg ataagccgcc accattcacc gtttgcgaca 515461 cctagattat agcctgtgac ggtatccctc cataacacga ctgaatgggc aggaagtgaa 515521 aaaaacagcc agagaacagc ttgcaaagcc aatataaagg tgacaacggg gtaaagcctg 515581 ataaatgttt gaaaattttc agtccgtata aacattccga gccccttttc ttcattttgg 515641 tatatctata gtaacacgtt tatgagacaa accatttaaa tagtacgtac gcaaaggagg 515701 ttatcataca tgatttacgg cattgggctg gacattaccg agcttaaacg gatcgcctct 515761 atggctgggc gccagaaaag gtttgccgag cggattttga cgcgaagcga gcttgaccaa 515821 tactatgagc tttcagagaa aagaaaaaac gaatttctcg cgggcagatt cgcggcaaaa 515881 gaagcgttct cgaaagcatt tggcaccggc attgggaggc agctcagctt tcaggacatt 515941 gaaattagga aagaccaaaa tggcaagccc tatatcattt gtacgaaact gagccaggcc 516001 gccgttcacg tatcgatcac tcatacaaaa gaatacgctg ccgcgcaggt tgtgattgaa 516061 aggttgtcaa gctagtctgc atattaggga aaccccactc atatatttga tagtgcatta 516121 agggagacaa gttgtttgag gcttttatgg tacgcatctg ttctgcctaa acgtgtaccg 516181 agcgtaccgt taaagtcaaa caagcgattt cttcctttta catcaattga gaaaaagggg 516241 ttgaaaaagg tgagaaaaag ctttgttttg cttttaacgg gactgcttgc tgttcttatt 516301 ctttctgcct gcgggcaaaa aacacagcaa gatattgtgg ccgggttaga tgaaaaggcg 516361 aaagaataca cctcgtacaa agcaaaagcg aaaatgacca tcgagacagg gagtgagcct 516421 caagtataca atgtggaaat ctggcacaaa aagccgtctc tgtacagggt ttatttagaa 516481 aatccgaaaa aggaccaaaa ccaagtcatt ttacgaaatg aaaacggagt attcgttctc 516541 acgccgtctt taaataagag cttcagattt caaagcgatt ggccgaacaa cagcagccag 516601 gtttatctgt ttgaatcgct cgtaaaggat gttcaaaacg attcggatgc agttttcaca 516661 gcgaaagaaa agaaatacgt atttgaaaca aaaacaaact atcagcataa caaaatgctg 516721 cccacgcaag aaatcacatt taacaaaaaa gatatgagcc cgtcatctgt caaagtgatg 516781 gatactgacc ggaaagtgat ggtcaaagta gaattcagca gctttgaatt taataaacaa 516841 tttgataaag aatcatttga tgaaaagaaa aatatgaccc tttctcaaat ggatgtcgcc 516901 acaagcgcaa agccttccga tacatttgcg gtcaaaacgc cgctggaact gccgcttggc 516961 gtcaagctgc ttgaagaaaa agatatatct actgaagacg ggaagcgcat catcatgacg 517021 tacggaggag aaaaatcatt tacgttaatt caggaaaaag cccagattgc caaggcttcc 517081 tcctccgtta cgctgaacgg cgaaccggta aatctcggct acaccatcgg cgccctgtcg 517141 gatgcatcat tatcatggac atatgacggc gtagattacc ttctctcttc taaagatctt 517201 tctaaagagg aaatggtgac agtagcgaaa agcatgcagg gacaatcatc gaaataaccg 517261 ccaaaggcca aacatgattt ggcctttttt tcgttagaca tcgtttccct ttagccttta 517321 attttagtat gatatgtaaa tgatattgaa taaaagctag gaagtgtcgt aatgagcaca 517381 aaaccttttt acagagatac gtgggcggaa attgacttgt ccgcgataaa ggaaaatgtc 517441 agcaatatga aaaaacatat cggtgaacat gtccacttga tggcagttgt gaaagcaaac 517501 gcctacgggc atggtgatgc agaaacagca aaggctgctc ttgacgcagg tgcttcatgc 517561 ttggccgtgg ccattttgga tgaagcgatt tcactgcgca aaaagggatt gaaggcgcct 517621 atattggtgc ttggcgcggt tcccccggag tatgtggcaa tcgctgctga gtatgacgtg 517681 accttaacag gttattctgt tgaatggctt caggaggcag cccgccacac gaaaaaaggt 517741 tctcttcatt ttcatctgaa ggtcgatacg gggatgaaca gacttggtgt aaaaacagag 517801 gaagaagttc agaacgtgat ggcaattctt gaccgcaacc ctcgtttaaa gtgcaaaggg 517861 gtatttaccc attttgcgac agcggatgaa aaagaaagag gctatttctt aatgcagttt 517921 gagcgcttta aagagctgat tgctccgctg ccgttaaaga atctaatggt ccactgcgcg 517981 aacagcgccg ctggactccg gctgaaaaaa ggctttttta atgcagtcag attcggcatc 518041 ggcatgtatg gccttcgccc gtctgctgac atgtcggacg agataccgtt tcagctgcgt 518101 ccggcattta ccctgcattc gacactgtca catgtcaaac tgatcagaaa aggcgagagc 518161 gtcagctacg gagccgagta cacagcggaa aaagacacat ggatcgggac ggtgcctgta 518221 ggctatgcgg acggctggct ccgaaaattg aaagggaccg acatccttgt gaagggaaaa 518281 cgcctgaaaa ttgccggccg aatttgcatg gaccaattta tggtggagct ggatcaggaa 518341 tatccgccgg gcacaaaagt cacattaata ggccggcagg gggatgaata tatttccatg 518401 gatgagattg caggaaggct cgaaaccatt aactatgagg tggcctgtac aataagttcc 518461 cgtgttcccc gtatgttttt ggaaaatggg agtataatgg aagtaagaaa tcctttattg 518521 caggtaaata taagcaatta acttacctaa atggagaatt cataaaacag ctttgcttga 518581 agagtgaata atggtatcat tatcactgga tggataaaag agtcgtatcc gtaagtttgg 518641 tggaggtgta tgttttttgt ctgaatccag cgcaagaacc gaaatgaaaa tcagcttgcc 518701 cgaaaaccta gtagctgaat tggatggtgt agcgatgcgg gagaaacgaa gcagaaacga 518761 actgatatca caagcagtga gagcgtatgt cagcgaacga acaactcgtc acaaccgtga 518821 tttgatgaga cgcggctata tggaaatggc gaaaatcaac ctgaatattt cttctgaggc 518881 tcactttgcg gagtgcgagg ctgaaacgac agttgagcgc ttagtcagcg gaggataatc 518941 atttgattgt gaaacgcggc gatgtttatt ttgctgattt atctcctgtt gttggctcag 519001 agcaaggcgg ggtgcgcccg gttttagtga tccaaaatga catcggaaat cgcttcagcc 519061 caactgctat tgttgcagcc ataacagcac aaatacagaa agcgaaatta ccaacccacg 519121 tcgaaatcga tgcaaaacgc tacggttttg aaagagattc cgttattttg ctggagcaaa 519181 ttcggacgat tgacaagcaa aggttaacgg ataagattac tcatctggat gatgaaatga 519241 tggataaggt tgatgaagcc ttacaaatca gtttggcact cattgatttt tagacatatt 519301 tgcaggttgc tcaaatagag caactttttt tgttttcaaa aaacataaac gatataatag 519361 tgaaataacg aaaaaatatg ttgtttttta ttgggaggta agcgaatttg atgtcgaacc 519421 agactgtata ccagttcatt gccgaaaatc aaaatgaact gctccaactg tggactgaca 519481 cactaaaaga attaagcgag caagaatcct atcagctgac tgaccaagtg tatgaaaata 519541 tatctaaaga atatatcgac attctgctgc tgtctgttaa ggacgaaaat gctgctgaaa 519601 gccaaatcag cgaactggcg cttcgagcgg tccaaatcgg actgtctatg aagtttttgg 519661 ctactgcact tgccgaattc tggaagcgtc tctacacgaa aatgaatgat aagagattgc 519721 cagatcaaga gagcacggaa ttaatctggc agattgatcg ctttttcagc ccgattaaca 519781 cagaaatttt taatcaatac tcaatctcat gggaaaaaac agtatccctg caaaaaatcg 519841 cgctgcaaga gctgtctgcg ccgcttatcc cggtgtttga aaatatcact gtgatgcctc 519901 ttgtcggaac aattgatacc gaacgcgcga aacgaattat ggaaaacctt cttaatggcg 519961 tcgtcaaaca ccgttcccaa gtcgtgctga ttgacattac aggtgtccct gtcgtcgata 520021 cgatggttgc ccatcatatt attcaggcat cagaagctgt aaggcttgtc ggagcaaaat 520081 gcctgctggc cggaatccgt ccggaaattg ctcaaacaat cgtcaacctg gggattgatt 520141 tatcccaagt tataactaag aataccctgc aaaaaggaat tcaaacagca ttggaaatga 520201 cggatcgaaa aatcgtttca ttgggggaat aacattttga gacatccgaa aatcccgatc 520261 ttgaaactgt ataattgctt attagtgtcc attcagtggg aacttgatga ccagacagca 520321 ttaacttttc aagaagactt attaaataaa atatacgaaa caggtgctaa cggagtcgtc 520381 attgacctga catctgtgga tatgattgat tcatttatcg cgaaagtgct gggggacgtc 520441 attacaatgt ctaagttaat gggggctaaa gtcgtcttga ccggcattca gcccgctgtg 520501 gcagtgacgc tgattgaact tggaatcgcg cttgaggaaa tcgaaactgc gctcgactta 520561 gagcaggggc ttgagacatt gaagcgggaa ttgggggaat agcgaatgaa cgaccaatcc 520621 tgtgtaagaa tcatgacaga atgggatatt gtggccgcca gacagctggg acgaaacgtt 520681 gcgaaagaac tgggtttcgg cacggtagac caggctagaa ttacaacggc tatttcagaa 520741 ttagccagga atatttattt atatgccggc aaagggcaga ttggaattga acaggtcgca 520801 gacagaggaa aaaaaggcct gaaaatcata gcggaagacc aagggccggg aattcctgat 520861 atccgaaaag tcatggaaga cgggttttca acgtctggag gacttggtgc gggacttccc 520921 ggggtcaaaa ggctgatgga tgaattcagc ttaaattccg tagcggggga aggaacagag 520981 atacaagcca tcaaatggct tcggtaggag gtaagaacgt ggattttagg gaggttattg 521041 agcagcggta tcatcagctg cttagtcgat atatagccga attaacagaa acatctttat 521101 atcaagccca aaaattcagc cgaaaaacaa tcgagcacca aattcctccg gaagaaatca 521161 tcagcattca cagaaaagtg ctgaaggagc tgtatccaag tctcccggaa gatgtgtttc 521221 attcgctgga ttttttaata gaagtcatga ttggctatgg aatggcttat caggagcatc 521281 aaacccttag agggatacag caggaaatca aatcagaaat tgaaatcgcg gcaaatgtcc 521341 agcagacgct tctcggaact aaagttcctc aggaggaagc gctggatatc ggcgccatca 521401 gtgttcccgc taaacagatg agcggtgatt actaccactt tgtcaaagac aaggaatcca 521461 tcaatatcgc aatcgcggac gtgatcggaa aaggcattcc agcggcttta tgcatgtcca 521521 tgattaaata cgcaatggac tctttgccgg aaacgggcat acacccttct caagtgctga 521581 aaaatttgaa tcgtgttgtt gaacaaaacg ttgatgccag tatgtttatt acgatgtttt 521641 atgcgaatta caatatggac aagcatcaat ttacatatgc ttcagcggga catgaaccgg 521701 gattctatta ttctcaaaaa gacaacacgt tttacgattt agaggccaaa ggactcgttc 521761 tcggcatctc gcaggactat gactacaaac aattcgatca gcatctggaa aagggcgata 521821 tgattgtttt attttctgac ggcgtcacag aatgcagaac ggaaaacggt ttcttggagc 521881 gtcctgatct gcagaagctc attgaggaac atatgtgttc ctctgcgcag gaaatggtca 521941 aaaacattta tgacagcctc ctcaaattgc aggattttca gcttcacgat gattttacgt 522001 taattgtttt gcggagaaag gtttaacgtc tgtcagacga gggtataaag caactagtga 522061 tttgaaggaa aatttgaggt gatacgaatg aatataaatg ttgatgtgaa gcaaaacgag 522121 aatgatatac aagtaaacat tgcaggagaa attgatgtat actcagcccc ggtgcttaga 522181 gagaagctcg ttcctctggc agaacaagga gctgacttaa gaatttgcct gaaagatgtc 522241 agctacatgg acagtaccgg attgggcgtt tttgtaggga cctttaaaat ggtgaaaaaa 522301 caaggtggtt cgctgaaact tgaaaatctt tctgaacggc tgatccgact gtttgacatt 522361 acaggcttga aggacatcat tgatatttct gcaaagtcag aaggtggagt gcaatgaaga 522421 ataatgctga ttacatcgaa atgaaagtgc cggcccaacc tgaatatgtg ggaattataa 522481 gactgacgct gtcaggggtc gcaagcagaa tgggctatac gtacgatgaa attgaagact 522541 tgaaaatcgc agtcagtgag gcgtgcacaa atgcggttca gcacgcttac aaagaagata 522601 aaaatgggga agtgtcaata cgattcggtg tgtttgaaga ccgtttagag gttattgtgg 522661 cggatgaagg agacagcttt gactttgatc aaaagcagca ggatctaggg ccgtacacac 522721 cttcgcacac agttgatcaa ttatcagaag gagggctcgg tctatattta atggaaacgc 522781 tcatggatga agtcagagtg caaaaccact ccggcgtcac cgtagcgatg acaaagtatt 522841 taaatgggga gcgagttgat catgacacaa ccatcaaaaa ctacgaaact aactaaagat 522901 gaagtcgatc ggctcataag cgattaccaa acaaagcaag atgaacaagc gcaggaaacg 522961 cttgtgcggg tgtatacaaa tctggttgac atgcttgcga aaaaatactc aaaaggcaaa 523021 agcttccacg aggatctccg ccaggtcggc atgatcgggc tgctaggcgc gattaagcga 523081 tacgatcctg ttgtcggcaa atcgtttgaa gcttttgcaa tcccgacaat catcggtgaa 523141 attaaacgtt tcctcagaga taaaacatgg agcgttcatg tgccgagacg aattaaagaa 523201 ctcggtccaa gaatcaaaat ggcggttgat cagctgacca ctgaaacaca aagatcgccg 523261 aaagtcgaag agattgccga attcctcgat gtttctgaag aagaggttct tgaaacgatg 523321 gaaatgggca aaagctatca agccttatcc gttgaccaca gcattgaagc ggattcggac 523381 ggaagcactg tcacgattct tgatatcgtc ggatcacagg aggacggata tgagcgggtc 523441 aaccagcaat tgatgctgca aagcgtgctt catgtccttt cagaccgtga gaaacaaatc 523501 atagacctta cgtatattca aaacaaaagc caaaaagaaa ctggggacat tctcggtata 523561 tctcaaatgc acgtctcgcg cttgcaacgc aaagctgtga agaagctcag agaggccttg 523621 attgaagatc cctcgatgga gttaatgtaa tgatccaggt tgaagaaaac gagcatattc 523681 aaactctagt atatcaactg aataaagaag ggaaatcgat ttgcggtgac agttttttta 523741 tgaaagctga tgataaggag ttaatttgcg cggttgctga cggactggga agtggatcac 523801 ttgctaacga atcctctgca gccatcaaag acttagtgga aaactatgcg agtgaagacg 523861 tagaaagcat tatcgaacgc tgtaatcagg cgatgaaaaa caaaagaggc gctacagcat 523921 ctatcctgaa aatcaatttt gagcaaaggc agtttacgta ctgctctgtc ggaaatgtac 523981 ggtttattct gcattccccg tctggtgaaa gcttttatcc tctgccgatt tcgggctatt 524041 tatcaggcaa gccgcaaaaa tacaaaacgc acaccgccac ctatgaaaag ggttcaaagt 524101 tcattataca tacagatgga ctcaacgtac ctgatatccg ctcccatttg aaaaaaggcc 524161 aatcggtaga agaaatatcg aattcgctga aaatgtatac gacatcgaga aaagatgacc 524221 tgacctatat tctcggacag ctgtcctaaa aaaccagaaa aagaagctgg acatccggct 524281 tctttttttt gcggttgact attaataagt gcgcttatta taattaataa gtgaacttat 524341 cattctggga gcttatggga tgtggaatta tgaatacaca gcgatagctg atgtggatgt 524401 gggaaaacct ggaactgtta tcaggaaaca gaaacaatgg atcaatggga gacgggtatt 524461 gcatcagatt ctttgaaagg acaatttcaa aatggaacgg aaggaacatt gcttctgcaa 524521 ggaaaaacaa ttctcttatg gcttgagcat gtggagaaac atcgggcgtt ttctgtcatg 524581 gtcaacatgc ccgcatagca atgtaataat ggagtttttt cacgtgcttc aaaagcaaaa 524641 agaagatttg tgtatcacat atggaattgt attagaaggc gctgaagcaa aaaagtgggg 524701 agaaatcatt gggactgaac tgtctaaaga catgccgacg gctgtcagca ggcttgtcca 524761 tctttacgga ggagtgataa aatgaacaca aattactgga tcggcgttgt gtcagagcaa 524821 catgtattaa aaggcgctgc cggcggtttt gcacagctgt gccatggaaa aaaagccccg 524881 ctcgccaaaa tgaaagaggg agattggctg atttattatt ctccgagaga cgcatatcca 524941 gacggcaaac tgctgcgaag ctttactgcg atcggcaaag taaaaagcgg aaacatctat 525001 ccgtatcaaa tggctccgaa ttttattcca taccgattag atatagacta ttatccatgc 525061 cataaaatcg gtttttacga cattaaatca aagcttgaat ttgttcagga aaccaagcat 525121 cttggctttt tatttcgcag aggacacttt gaaataagca aaaaagattt tttgacaata 525181 gcacaagcga tgggagttaa cataagtgga atggcactct aaatttagcg gtccgaacac 525241 aagcccgggc tttttattat ggcaggccac gcaaagttgg cagcggaaag taggaaaagc 525301 attggctgag tttgacctga cccacgttca atttgttctg ctgacctcgt gcaagtatat 525361 gattgctcac ggagaaaccg tcacgcaaaa aaaacttgca agcttcagcc agaccaatat 525421 catgatggtt tcggaggttg tgcggacgct tgagaaaaaa ggatttatcg aaagaagcaa 525481 aaatccccag gataaaagag aggtcctcct gtctcttaca gaaataggag gagaaaaagt 525541 aacagcggct ttgccaattg ttgagaagat tgatcaagcc ttctttgcag ctgcgatgaa 525601 aaaagagaat tttctgagcg gcttacagga actattgaaa catgagtaaa gatacgggca 525661 gcgccagctg tcttttttta tgtgtttttt tcggtttttg atacactaga gaaagaacga 525721 caaaattgga ggctttggtt acatggaaac gtcagccctt ttaaaacagc aaattgcgaa 525781 agaaataggt ttatcacaaa aacacgttga aagtgtcatc cgcctgcttg aggacggcaa 525841 tacagtcccg tttattgccc ggtatcgaaa agagcagacg ggttcaatgg atgaggttca 525901 gattcagacg atttctgaac gctggcaata catacaaaac ctgaatcagc gaaaagaaga 525961 agtcatcagg ctgattgcag agcaggataa actgacagat aatctaaaac gtaaaatcga 526021 gcaatcggtg aagcttcagg aagtggaaga cctttaccgc ccttataaac aaaaacgtaa 526081 aacaaaggcg acagtcgcca aaagcaaagg ccttgagccg cttgccgact atatcctgac 526141 acttccccaa gatgatcatc tggcagcaac tgcagaccaa tacatcagcg aagaaaaaga 526201 agtgttcaca cgagaagaag cgattgaagg cgccaagcac attattgcgg aacaaatctc 526261 agacgagccg accttcagaa agtggattcg ccaggaaacc ttcaaaagag gaaccattaa 526321 gtctgcagcc ggaaagtcgg cagacaccga tgagaaaaat gtgtatgaaa tgtattacga 526381 gtatgaagag ccaattgcaa aagttgttcc gcatagggtg ctggcaatga accgcggcga 526441 aaaagaagac attttaaagg tagcgatcga accgcctgcg gatcacatta aggcgtattt 526501 agaaaaacaa atcatcaaaa atcgctcaac atccgtaaga gagattttgc aggagacaat 526561 tgaagacagc tataaaaggc tgatccagcc ggcaatcgag cgtgaaatca ggaaagagct 526621 ctcagaaaaa gctgatgaac aggcgattca tattttctca gagaacttga gaaagcttct 526681 tttgcagccg ccgatgaaag gcaaaaccgt tctcggtgtt gacccagcct ttcgaactgg 526741 ctgtaagctc gctgtgtcag atgagaccgg aaaagtcttg aaaattgatg tgatctatcc 526801 gcatgcgcca gtcaacaaaa caaaagaagc ccatgaaaaa gtgaaaaaga ttcttgagca 526861 gtatcaagtc gagatggtgg cgatcggaaa cggcacagca tccagagaaa cagagcaatt 526921 catcgtcaat gtactcagag acatgccgcg caaaatttat tatgtgatcg tcaatgaagc 526981 gggagcaagc gtctattcgg cttcagagct tgccagagaa gaattccctg accttaaggt 527041 tgaagagcgc agtgccgtat ctattgctcg gagacttcaa gacccgctcg cggagctcgt 527101 taagatcgat ccgaagtctg ttggtgtcgg acagtatcag catgacgtca gccaaaaacg 527161 cttaaatgaa tctctgcggt ttgtcgtcga aactgtcgta aaccaggttg gagtaaacgt 527221 caacacagcc tccgccgcgc tgcttcaata tgtagctgga ttatcgaagt ctgtagcagg 527281 caacgttgtc aaaaaacgtg aggaaatcgg aaagttttca aatcgaaaag aactgaagga 527341 catcccaagg ttaggtgcga aaacctatga gcaatgtatc ggtttcttaa gagtgcagga 527401 agggacagag cctttggata gaacaggcat ccacccggaa agctataaag aaacaaaagc 527461 acttttgaaa aaactcggac tttcaacaga acatatcggc acggcggaat tgaaggacaa 527521 aatcaatcag ctggcgctct ctgaaacggc aaaagagctg ggaatcggcg aaatcactct 527581 gaaagacatt tgtgaacagc tgacaaggcc ggaacgcgat ccacgcgata aggtgcctaa 527641 gcctttgctg aaaacagacg tccttcagct ggaagatttg aaagagggaa tggaactgca 527701 gggcaccgtg cgcaatgtag tggacttcgg agcgtttgtt gatatcggag tcaaacaaga 527761 cgggcttgtg catatctcaa aattgagcaa tcaattcgtc aagcatcctc ttgatgtcgt 527821 atctgtcggc gatattgtga cagtttgggt tgacggcgta gatgtacaaa aaggcagagt 527881 atcgctgtct atggtaaaat aaaagcactg cttacgagca gtgttttttc ctatagaaat 527941 accagcattg attcagcagt ttaatttggt aattatcttt ttcaaggaac gctttttgca 528001 tctgcttttt aagccaattt ggcataggct cattcctcct cagcttttat cataagaggg 528061 acagtgatta ccatattgta tgcgaacggt gaattgtccc gttcaatgtt ttttaagtga 528121 ggtgcaccat ggataacaaa gagcttcaaa agctgacaga ggatatttct gaaacatatt 528181 ttaaaaagcc gttccgccat caggcgcttt ttaatgaccg gcttaaaacc actggcggca 528241 ggtacctgtt aacctcccat aacattgaat tgaacagaaa atatttgatt gaacacggca 528301 gggaggaact gattggcatc atcaagcacg agctctgcca ttatcatctt catcttgaag 528361 gaaaagggta caagcacaga gacagagatt ttagaatgct attgcagcag gtcaacgcgc 528421 cgaggttctg tacacccctt aagaaaaaag cggaaaacaa aaaaacttat atgtatatct 528481 gtacgacctg cggccaacag tatataaaga agcgcgccat gaaccctgac agatacagat 528541 gcggaaaatg ccgcggaaaa ataaaaagaa ttttttcgtg aaaaaggttg acgaatatgg 528601 caagcctatg ttacattata aaagtcgtca cgagagataa ataaaaacat ttacctcttg 528661 acactgcaaa tcaaggctga tataataagt cttgtctcat tattccacag tagctcagtg 528721 gtagagctat cggctgttaa ccgatcggtc gcaggttcga atcctgcctg tggagccata 528781 ttggagaagt actcaagtgg ctgaagaggc gcccctgcta agggtgtagg tcgcgtaagc 528841 ggcgcgaggg ttcaaatccc tccttctccg ccataagatt tcgatataag ttctcaacca 528901 tcggcccgtt ggtcaagcgg ttaagacacc gccctttcac ggcggtaaca cgggttcgaa 528961 tcccgtacgg gtcattccat ttcgttgggc tatagccaag cggtaaggca acggactttg 529021 actccgtcat gcgttggttc gaatccagct agcccagcca tttttatttt tgaaatctaa 529081 tagtaagagc cattagctca gttggtagag catctgactt ttaatcagag ggtcgaaggt 529141 tcgagtcctt catggctcac catttgtctt tttgcgggtg tggcggaatt ggcagacgcg 529201 ctagacttag gatctagtgt cttacgacgt gggggttcga gtcccttcac ccgcacttta 529261 tttacaaagt gcacgcaaat ctgttttact aggttaagag cctactaaac cagcacaaca 529321 caatttaatg atcacgcggt cgtggcggaa tggcagacgc gctaggttga gggcctagtg 529381 ggtgaataac ccgtggaggt tcaagtcctc tcggccgcat caatgatacc aagggttttg 529441 acacccttgg tatttttttg tgtttatttt caaatgattt actgcccaca aactgcccac 529501 ttacctaaag taagtcatct aatttatcag ccatttcctt ttgcttgttt ggatataggt 529561 gtccataaac atcaattgtt gtttttacag aaccatgtcc taaacgctct ttaattgtta 529621 tgtaatcttc tccttggtgt attaatagtg caacgtgtga atgtctaaaa tcatgtaaac 529681 gtataggagt aagatcgcta tccttgcaaa agtatttaat tttccgactg aaaatatctt 529741 ttcttgaagg tgtatcttta tattgaaaga tataggtatc atgtgaatgt ctaataccta 529801 attcattaaa caactcttct tgtgcttctt tccaacgttc tagtagctta agcaattttt 529861 tattgatgct aactcgccga atcgaatttt tagtttttgg agtagtaaca acaaattgac 529921 catcaagcca ggtgcacgat ttatgcacat ctatttctaa taagattttg tcaatatctt 529981 tccattgcag ggcgagcatt tcaccacatc ttagtccagt taaaaaagca acagtgtaaa 530041 aggttttaaa caataattga tcttgaggaa ttaaactaat aaattttttg aattcttctg 530101 gtctccaaaa cttcattttc tttcttgtta aaggtaatcg tttaacgttg tcacacggat 530161 ttctttttaa gatttcttca tgtacagctg tatcaaaaat tttgcttaga ctagtcatta 530221 tattattaac cgatttattg cttagacctg tttccattaa atgttttctg aaatcagtta 530281 tttctctatg tgtgattttt tgtatatcag atttcaaaaa gtaatcagat atatgtttgt 530341 ttataatgta cttctgattc tgataatagt ttggtttact atctatttca caacttgcta 530401 aataaattga aattagagtc ggaaagctta ctgatctgga ctttcttgct ctttcttctt 530461 gaaattctct tcttaatttt gcttctaatt ctaaagcctc ttttctggtt gatgctactg 530521 gtctcgtcct aattctttct ccagtaatcg ggtcaaatcc aaagctaacg tcaacttgat 530581 attgaccatt ttcaagtttt tttacagaca ttttatttct cctttaacca aaagcgctta 530641 tttcgtgtga atagattctg ttactaaatg agccaatttg agaaagttta taatcagtaa 530701 caaatgatgg tacgttgaag tatgctgcta tttgttcttt gctaaaaccc tgtatatatg 530761 gaagggcttc attaagcatt ttatctgtca gtattaattc tgatgcaaat aggcttgctt 530821 gatgctcaag tttatctttt agaactttag agcaattcac aactttaaaa gtgttcaatc 530881 ttttatggag aaagtaatgc cctaattcat gggcaattac aaattgttga tgttggaggt 530941 tctcgttgat atggattaaa tattgatctg tggctttgtc atgttgtagt aaaccgtttg 531001 cttgtccaag atcatttttg agtatataaa ttttttggat gtcacaaatt tcatagacat 531061 tatttgtacc atgtgtctta attactgatt gcactttatg tttaattcct ttgcttgtat 531121 aaattgttat cactctttct tctttaattc gtcaatgaat ttaattccgt tttttaatgc 531181 ttttttaaca aggcgtgcag tttcctcatc aaattcacca tcattcataa aaaggagtgt 531241 atcttcatcc tttaattcct gtatggcttc attaattgtt ttattgagta aatcagtttc 531301 gtttttcttg cttacttcat cctttcctaa taaatagtct gtagatacgt tatataagtt 531361 gctcaatttt aagagtgtgt ctgtatcagg atctctgtaa tctctttcgt aattagacaa 531421 gttattgtta ccgatattaa gtttctctgc ggcttctttc tgagtgtacc cagctttttg 531481 tcgagcttct tttaatcgtt tgcctaggct catttttatc atccatttca caaagagttg 531541 atttttataa aaataataac aacatttttt ggagaattca ttaatttcac ctataagtta 531601 aataaataat tctaaattct ccttttagga gtgtttgttt cttctttatg gagagtttaa 531661 ttatcaatat ttccatatat gttcaaaaaa atacacttta aggtgaattt tgtgttgact 531721 tacacgaaaa ggagttttat aataaagtta attcacaaag agttgagtta acgaggaggt 531781 gatattttga aaggagagtt tttaactgcg agagatattc aaaaaattct tggagttaaa 531841 caggctaaat cttatgacat cattagaact ttgaatgctc aaatgaaaga agaaggatat 531901 atggtcattc aaggtaaggt gagtagagct aagtttgaag agtgttattg ttacaaaggc 531961 ccaaaatctc aaacggggtg atttttataa acattgatat aacaaactcg tttatgaaag 532021 aagctgtccc tttagctaga caaatggaag gtgattggat agcacgaatg aaaattgctc 532081 tgaattcagt cattataaat cattatttaa accttccctt aacaattgaa aatgttaatg 532141 aattactgcg aaaaggcgtt tcatatcgca ggatatgtaa gcattacggc attggaagaa 532201 aagacattga aaagcttcgg caatcatccg tagtgtgacg ttatatacca ctatagggag 532261 ccgttaagaa tcctttgaaa ggagggatgc gatgaaaata agagtgaatg caacaatcat 532321 tactgatgtt gaagctttaa aggctgataa ggatttgaat cattttaaag actatgccac 532381 ttgtgaaaca ttcgttgttg atgctgataa tcatttgaag gctaatgaag aaatatctga 532441 gttgttaaaa ggctgggatt ggtggtgtat ctggtcaact cgtccattga gtaaaaagga 532501 taaccaagtg tttactttgt ataacgatga tttgtataac ttatgtcgat aggagtgttt 532561 gttccttgaa aactacatat agacaaaaaa agcgccttga cgaatgatca tcaagaacgc 532621 cggaaaataa aaactagaca cttttattat acggtattct tgttgaaatg tcatgcgtga 532681 gtatttgagt gatgaacagc aatcacttta aatgctgtag caggctagaa taagcgtgcg 532741 gaatagctgt agtcagcttg atggctataa ttagcctact aggttgccat gagggcgtaa 532801 agccgttagc aactgataag cgccaagatg gatacagaac cggagcgaat caaaaacata 532861 aaatcgaaat taatgttctt ttgtaaataa attataaaaa aatgaaatgg ggatatgaaa 532921 aatgaactta aactttattg taccggatat caatatgact tttggagaca tgaaattcat 532981 gggacttaac agagaaaggt atgtttatga tcgtgaaaat aataagcgta ctgacgtact 533041 ggaatctagg atttataaca ttgctagtgc tgtccaaggt ggtcaaattg aagtaactat 533101 tcctgagtat gctggggcaa aagaaattcc tccttttgca gatattgagt tgaaaaatcc 533161 aaaaattagc gctatggcga ctagtcaaag ggattcgacg tatgccaatg tgatgtggaa 533221 acttgaagct gatgatattg ttgttaaagg tggctcttct gtgaaacctg ccgcggcaac 533281 tggcgggaat gaaaagaaat aacatgatgc tctcatatcg gcaggcgggt gatgtatatg 533341 agtgatttct taaacaaaag attttggaaa tacaggggca aacgaatccg cccgtacatg 533401 agaaacaacg taaagttagc aggcgcaatc atctttgtgc ctgttttttt attgtctatg 533461 ttcctttttt ggagagaaca actcattcat tttgatctat ctcaagtgat aaaaaatttt 533521 gaatggaatg tgcctttaat cattaaaagc gttttatgct ctgtgctaat tgctgttgga 533581 agcatagttg catcttactt tcttttgttt gacagctata agaaaatcct tcacaggcaa 533641 aagattgcta aaatgatttt ctctaacaag ttttacgaaa aagaaaacgt gaaagtaaga 533701 aaaatctttt caaatgaaac tgactcaaag gaaaagatca catactttcc tagaatgtat 533761 taccaggtca aaaacaacca catctatatt cgtattgcta tggacatgag ccgttttcag 533821 aatcgcttcc tagacttagg aaaggatttg gaaaacggct tattttgtga cttggttgat 533881 aaacaaatgg aagaaggttt tgtatgcttt aagcttcttt acgatgtcaa aaagaatcgt 533941 atttccattg atgatgcagt agctgagaat ggagtccttc cgttaatgaa gcatatctca 534001 tggcaatttg ataagttgcc gcacatgctt attgctggtg gtacaggtgg agggaaaaca 534061 tacttcatgc taacgatcat taaggcatgt gttggactgg gggcagatgt aagaatacta 534121 gaccctaaaa atgcagattt agcagacttg gaagaagtac ttccgaaaaa ggtctattcc 534181 caaaagaacg gtattcttat gtgcctgaga aagtctgtag atggcatgat ggaacgaatg 534241 gatgaaatga agcaaatgtc taactataag acaggtgaaa actatgctta tttaggctta 534301 aaacctgttt ttatcttctt tgatgaatat gtggcattta tggatttgtt agatatgaaa 534361 gaaagaaacg aagccctttc ttacatgaaa cagttggtca tgttggggag acaggcgggg 534421 tattttctcg ttttaggcgc acaacgtcca gatgcaaaat atttagctga cggtattcgt 534481 gatcagttta gctttcgtgt ttcattgggt ttaatgtccg atacgggtta cggaatgatg 534541 tttggcgatg ttgaaaaagc atatgtgaat aaaaaggaga cagggcgagg atatgccaat 534601 gtgggcacag gttcagtgtt ggagttttac agccctatcg tgccgaaagg atatgatttt 534661 atgtcatcta ttaaaaatgc gctggttgga gtcgagggag cgcaggcgac ggcagtcgcc 534721 agcggcagcg taagcgacca gacggccagc ggcgaaggag tgagcgaagc gaatggatga 534781 gctaaaacaa cccccccacg ctaacagggg ggtagtaatc gtaaaagaaa aaaatgaagc 534841 cgttgaaagt cctttggtat caatggttga ctatattcga gtctctttta aaactcatga 534901 tgttgacaga attattgaag aggttcttca ccttagcaaa gactttatga ctgagaaaca 534961 atctggtttc tatggctacg ttggcacgta tgaactggac tatatcaaag tcttttattc 535021 tgcgccggat gacaacagag gtgttttgat agaaatgtcc ggtcaaggtt gccgtcaatt 535081 tgaatccttc ttggaatgcc ggaagaaaac atggtacgac ttctttcaag attgcatgca 535141 acaaggcggt tcgttcactc gctttgattt agctattgat gataaaaaga catacttttc 535201 tataccagaa ctgttaaaga aagcccaaaa gggcgaatgt atttcacgat ttagaaaatc 535261 tgatttcaat ggctcctttg atctatctga tggcattaca ggcgggacga caatatattt 535321 cggttctaaa aagtcagaag cgtacctttg cttttatgag aaaaactatg aacaagcaga 535381 aaagtataac attccgttag aagaactagg cgattggaat cgttatgaat tgcggcttaa 535441 aaatgaacgt gcacaagtgg cgatagatgc tttattgaaa acaaaggatt taaccttaat 535501 cgctatgcag atcattaata actatgtaag gttcgttgat gctgatgaaa acatcactag 535561 agagcattgg aaaacgagcc ttttttggtc tgattttata ggcgatgttg ggagacttcc 535621 tttgtacgtc aaaccacaaa aagacttcta tcagaaatca agaaactggc ttcgtaactc 535681 ttgtgctccc actatgaaaa tggtgcttga agctgatgaa catttaggga aaaccgatct 535741 gtcagatatg attgcagaag ctgaactggc tgacaaacat aaaaaaatgt tagatgtgta 535801 tatggctgat gttgctgaca tggtcgttta aaaccaagct gctaaacctt aataaacaca 535861 ggtgatgcga ttaaacgtat gtgtcaacgg taccggaacg aagtgaggat aaggagttga 535921 catattcagc gctacccaaa ccctcttggc attgaacaaa caaccgtttg ttcctgccta 535981 ccggcgaggg agtcccccga tgattcgggg gaataggggg atagattaac agcaatccaa 536041 cgagctaccg ttggtgggtt tgggtgaaac ccaagaacta acttggaggg ataagatgca 536101 taatgtcaat ctgttgaatc aggctggact ggaaaatgct ttggaatcag ttggctgttt 536161 agatattgta gaagatttaa tagaaaagat gcaggaatat gttttgtatc ataccgaaac 536221 tgccgaaaga tttgcgattg atatctttac agtagtaaac aactacacta aaaaggttca 536281 tgcgatattt aatgttcttg aaaatgaaga cggtgagaca aatgttaaaa atgtagaatt 536341 tgaagtaatg cattttacgg agtaaggaca attttcctta tgactttaaa gggggaacat 536401 caggtgttta atattaatct gttgaatcag gcccgacttg agagtgattt ggattccctt 536461 gggtgtttgg atattgctga ggaactgatt gaaaaaatga tggaagatgt tttttacagt 536521 gatgtagctc aaagaatcat tgttcaaaca cttgctgtta taaataacgc caatgcaaaa 536581 cttcaagcta cgtttaacat cttagaagat gaagatatgg agacagacga acgaagcgtg 536641 gagtttgaag gaattagcta ctacgaataa ggggtgaaaa tgtgcggtgt ctgctgtaga 536701 taaacgattc aaaagcttag gttttaatgt gggcattccc tctttagttt ttgtgagaag 536761 tttaagcaga gattgcatgt tggttgttga aggagaacga gtaaaaggat ttgctgagta 536821 tcgttacaca ttctataaaa caagatactt gccagacggt cgaatgacta gcttaaaagt 536881 ttatatggag aatcaaagca taaaaagggt gttacatcgt gtagcatcct ttttatcttt 536941 cttggaaaga acgaaacaaa ttgaacagaa ggagtgtgaa aaagttgctc aataaagaaa 537001 ttggctctga taagaaggaa gaatcctttt ttcggtctgc ttttcaaaaa ctgaaacgaa 537061 ttgaaagacc ggaaaaagac aaacaaaaag taccccgtga caggtcaaag ctgatagccg 537121 tcacactatg gtcttgtgta gggagcttgc tatttatctg tctgcttgct gtgcttctgt 537181 caattaatac tcgctcccaa cttaatgaca tgaaagacga aacgaataag ccaacaaatg 537241 acgataaaca aaaaatttcg gtgactgctg ccgaaaactt tctgtcaggg ttcatcaatg 537301 aatatatgaa tgtgaagaac gatcaagaat ctattgaaaa acgtatgcag agccttgaaa 537361 gctatatggt taaacaggaa gataaccatt ttgaagatga agaacgcttc aatgtggatg 537421 gtttaaaagg tgatcgagag ttaaagggtt acagcttata taacgtgaaa gaaggtgata 537481 aaaacagcct ttttcaatat aaggtcacat atgaaaatct ataccctgta gaaaaggaag 537541 ttgaaaaaga agttaaagac ggaaagaaga aaaagaaggt gaaagaaaag gttaaaacaa 537601 acgagaaata cgaaaaacaa atgttgctga atattccagt cacaaataaa ggtgattcct 537661 ttgcggtgtc tgctgtccct tattttacac agatttatga tctgaaaggc gatattgctt 537721 ttaagggtaa agaagaaact agagacgaat atgcaggcga gaaaaaagaa tctatcgaat 537781 catttcttca aaatttcttt gagaaatacg cttctgaaaa gaaagaagaa atggtttata 537841 tgatgaaaaa gccggaagca ttggaaggaa acttgttatt tggggaagtg cagtcagtga 537901 aaatcttcga gacgaaaaaa ggtttcgagg ttttttgtgc tgttcgattt aaggaaaaag 537961 aaaatgacat tccggtaaat gaaaaattca gtctagagat tacggaaaac agcggtcagt 538021 tttatgtaaa taaactcaaa catcaatagg aggtttaaat atggatttca tgaatttctt 538081 tattcttggc gcagaccttc caacacttgg aggggtaaaa ggttgggcat cagatgttgt 538141 tatccaattc attacgattg tggtcatgtt catagccgca aagaatctga tgaaattaaa 538201 aatgggcggc attatctttg tttgctgtat tggcagtgcg gtaacgtggg ttattaaaca 538261 ctggtcagaa ttctccggct ggatcaatgc gctaatggaa aaattgtaag ggggcatctg 538321 aatggggcgt ctggtgttca actaccggaa ggcaatgaga gagccgaaaa aaatccaaca 538381 attaaccgaa aattattcgt taccctttgc agttgagtta ataccggcta ttaactattt 538441 catttttgtt ggcttatgct ttggattctg gtacggcgtg aggatgattt tccctcacgc 538501 ttttgataac agttacgtca ttgtgatttt tgggatacca ttttttttaa cgatgcttgt 538561 aacgaaaata aagccggaag gcaaaaacat ctatatatat ttctttgatt tcgcaaagta 538621 ttacttcttc atcaagcttc cacaaaagaa gtattgcaat gatcgaaaga ttgatttaag 538681 taacgaaaaa caaattgagt ttcgaaaact tgtgaaggtg gtggattatt caaatgagac 538741 taaaaacgcc tatgaaggca atacacaaga atttgctgtt aacaagaacg ggcgacgtgt 538801 gggcgtacta ccgaataaaa agcaattcga ttcctatgca aaataaagaa aaagttgaat 538861 cgtataaaaa gaagtggcag catctttttg aagaaattac atcttatgag gattttcact 538921 tgatgatgta tccaagtgag tatgaattag aaaaacgatt taaggattta gaaacagata 538981 ttgcggcaga tgcaatggat gtggcacgtt actacaatga agaaaccgta aggctgttag 539041 aacagcgatt aggaaggctg acaaagtacg acttcatttt aggtgtaaaa ctgaaaagca 539101 gtcttgtaaa tattagtgtc gaacttaaag acaatatact atcttttttc aatacagcga 539161 ctgatacagt cgtgaaaatg ctcgggtggg aacaaaatgt ttccacctct ttttttgaaa 539221 aatatgagga agtcgaagaa acactagcga atatcatggc ttctgttcgc ggagaacggc 539281 tttcagaaac agaaatgaca tacattaacc gttatcactt tgtacgtggg ttaaagcacc 539341 aaacgaatga agaaagtgag ataaaggatg ttcgctctat tacaaacacg atcatagacc 539401 ccactgaccc atcagtattg catttgcata gtgatcaaga tgaaggctat tcagcttttg 539461 tcgtgattga cgaatttctt cacaatatgt cggaaagtga tttgttttat gaagcacagt 539521 ctcttccctt ccctgttgaa gttcagatga aaattcaaac ggaatcaaag tccattacca 539581 agcctgccct caacctcaaa agacagcaat tgaaagaaga acaaaaagaa caacaaagca 539641 caggcgatcg aagtgatgtt tccactgtca caagtgccac aatgataagg catttacaag 539701 atgaaataaa gaaagaagat gtgcatgtga tgaactggct gtcggtgata gtcgttcatg 539761 gaaagacaaa aaaagaatgt gtgggaaaag caacgattgt caaaaggcat ttaaaaggcg 539821 ctggcattac ttgtcggctt ccggtggctg atcaattgaa ccttttttat aaaatgcttc 539881 ctggtgaaaa gttagacata accgataaga actggattca aaaaacaacg caagacggtg 539941 tggctgaaag tctgtttgct gttaactctg atattggttc gaaaatcggg ttctttctcg 540001 gttgggttga tcgtttccaa gagcacaccg acttagaaag tgccattatg tccagccgtg 540061 attttgtctt attccaccct ttcttagcga atcagcagtt aaaaggttca aagacacgtt 540121 ctcctcactg cttaatcaca ggagacacag gaaacggcaa gtcatatcta gcgaaattga 540181 tctttaacta tatcagcatg ttaaacatca aatctctgta tatagaccct aaaaaggaaa 540241 tgagaaagtg gattcaaaga gtcttgaatg atgagtacat tagagagaac tttcccttat 540301 atattgcaca tttagagaaa tacaactata tcacgctaga tcatgaaaac acgcacaact 540361 ggggagcgct tgaccctatc tccttcctcc ctcctatgaa agcaaaagag ctagttcaag 540421 tcatttttga acaagtatat gactttaaag ggaaggacga cataaacaca gctttccttc 540481 gtgctacgtc agaagtgatt gatgcgaaac aaaaaggtga acaggtcggc tcacttgata 540541 ttattcggaa gatgcagagc catcccgaag aagctgtaca aaaagctggt gactatttaa 540601 atgaggtcgt gtcagattcc attttgaaac tttgtattca tgatggttca aatcctgcat 540661 tgtcactaga aaagcgaatt accattttag aagttgaaaa tatggatttg ccggatcatg 540721 ctgagcgact tgaaaactac acgatatcac aactaaagtc tagtgcggtc atgtttgcac 540781 taggtaagtt ctgcgagcta ttcggcatga atcaagacga acagactgtt gaatttatag 540841 atgaagcttg gatattcacc acgtcacaac aaggaaaaaa agtagaaaga caaatgcgcc 540901 ggattggtcg ctcatacaac aatgcggaat acttcatttc tcaatccaca aaagacgctt 540961 taaaagaaga ggattctgga aactttggcg ttgcctttgc ttttgacgaa ccaaacgagc 541021 gtgaagaagt gttgaaatgg atgaacatgg aggtcacaaa agataacaaa aaaatgatgg 541081 aatccatgtt tcaaggtcaa tgcttattta aagattacta tggccgcacc tctaaaattt 541141 cgattgaatg cctattcgaa gaatggcaag gtgctctgaa aacagttgag aaaaaagccg 541201 tcgcatatgc ggaagaaaaa tatttgtaaa aaggggttga atcgtacatg gaaatagctt 541261 tcttaaactc tcttgttgtc acgagtccag gcttttataa agctgagaaa atcacattgg 541321 acgaagttaa acaatggctg aagcattatg atggtcgata caaaagtttt atcggacata 541381 aatcaacggc acagtttctg caaaaattat taggtatcag aattgagcaa aatcgaaaga 541441 ctttcagaca tatgaaatat caaaaagcaa tctgtttctc tctgtatgaa cgatatcctg 541501 aaaacgtgtt gctaacgcaa agagacttag agaaagccag ataccaattt tatttattaa 541561 ctcggttaga ttaggaggtg gttgtaatga aaaagaaaag aattttgatt gtgtcggcta 541621 ttgtgttgct gtttttaact gttgcttcag ctgtaacggt attttcggct gatggagata 541681 caacgacgca gccaaaagtc gaaaaagctg gcggcgtgga attgaaggtg aaaaggtttc 541741 caatctcacg ctatcaagcg aataatgaag catctgacga tttaatcaag ggggcgtttg 541801 ttgggctgac aaacgtcact ttttcttttg cgggaaacat tgtccgtgtg gttgatacgg 541861 ggatggatat tttgtataac ttgcaaccga ttgacgagtt cgcaaattct attacaaacg 541921 tctctaaaac agtttataaa acactgaaaa agaatttcgg tgaagcttta tttattttca 541981 cgtgcgccta tgttgtctac ctattctgtg tgagaggtag cgtaaaagaa gcaatgcggc 542041 ggagtattct atttatttgt gtcatggtga tcggtgggct ttggatgtcg aacgctggtt 542101 attacatgaa agtattgaat gccttgtctg tagaagctca aggaaagctt ttaactgcgg 542161 ggaatggatt ggttggcatt gttcaagatg aaggcaattt tgcagacagt tcagcgattg 542221 aaaaaggaaa agaaatggaa ggcacagttg cggttatgcg taatctttac tttgacattg 542281 ctttgatgaa gcctttttta attgtgaatt ttgatgaaac aagcgaaaag aaaatcaatg 542341 aggaagatac agataaaggc ggacttaatc gtatagataa actgctttct tataagcttt 542401 cagaggatgg agaaaaagat aaaaaagatt atataaaaga gactgaaatt gatgattata 542461 aaaatgaatc tatgacttct ggaaatgtgt ttaatcagct gggagagtct tttatcgctg 542521 tggtcgcttc tattgtcatt gggataccat ttttagcatt agcgttcttt aatttcttgc 542581 ttcaagttgt cgctttagtg atagttttct ttgtgccatt tgctttcatc ttagcgtatg 542641 ttcctcaatt agcttattcg ggatttgtta cgcttggacg cttggggagt gtttacctac 542701 tgaaagcaat gttaggggtt atcgttctgt ttgtgtacgt gacttgtttt attgttgaca 542761 agttaatacc gccaaatggt tttggaatgt atcttttaaa tgttgctgtc cttgcttcaa 542821 tcttgtggat tggttttcac aagagggatg ccattatcaa gtttgtgact gctggaaaag 542881 ttgtttcagt tgataataat atgatggaaa acatgagaca aaacattgtt cagcctgctt 542941 gggaacaagc gaagaaaata ggtggagtat ggggtaacgg aggcggcgta tttactgact 543001 ttacaaagca ttttggggga agaaaagacg gttcgaatgc tgatggcgta actggtgctc 543061 caagtggtgg cggtaattca ccgagtggga ctgctatggg atatgataat actcatgcta 543121 tttcaagaac cccgcaaaaa gaaacagcta acggaatagc taatcataac agtcgaagct 543181 taaaacgcaa tcctcaaact ctatcgaaag aacaagaaaa gcaaaaacaa aaagaagcct 543241 ttgcaaatgc aaaagaaaat aaacagcaat cccatttagc cagattgaga aaagacggaa 543301 taaactctcc tatgttgaaa gatgctttga atgaagggaa tgaggattta tccaaacgag 543361 cacctatctt gcaggataaa aaagatgaat cagcacgaac agatcaaaaa gaatatgtgg 543421 aacagcttct taaacagccc aataaccagc aacaaactga cgatgcatca ttacagcatg 543481 aagaagaatc tacttctaat cgtgcgcctg tcttacaaga gaatgaaaaa gatacagaac 543541 gtactgatca gaaagcgtat atttatgacg aacaaaatca gaatcttgaa acagatcagc 543601 aacaagattt tgaagtccag aaagatgatt ctgtttccaa tagtgagcct gtagcacaag 543661 agaaaacagc agaaatcaaa cgatcagatc aaaaagtcat gatgaatcaa cctgaaccgc 543721 agctcggttt tgaaagtcct caatctacaa aagtagaaaa tcaacctatt gccaataacg 543781 aacgtaaaat cagaccatct gaacccgcaa aagttcattc agatggtatt cgtgttgatg 543841 aaaaacaggc tgttgctcct gctgaaaata agactgtatc aagagaaaaa cagccttcat 543901 cacaaacaat taaacggact gaacaaagcg ttaattcatt tgaccaagtg tctttgaatg 543961 aaattgcaag acgctcttca tcaaaagtag aagatcgact gagaagggat gaaagaacaa 544021 gatgataagt aaaaaggtag ttcttccttt ggtattctcg gctcctttta tcttcttttt 544081 tgttttatgt atcgtagtgg ttatgacgat ttcaagagaa aatcaagtcg gggacgattt 544141 tataggcggc ggggatggcg aatatgaaac agttggaatt gcgccggaag tggaacgatt 544201 tagagcagta tttgagaaat atgcccgtca agaaggcgtt tttgaccaag tgaatattat 544261 tatggcgctc accatgcaag aaagtggtgg gcgttcttta gatatcatgc aaagttccga 544321 aagtatcggc ttacctccca actccataac tgacccagaa cgttcaattg aagtcggcat 544381 taaacatttt aagaaggttt ttaaacaggc tggcggtgat gttcgtttaa ccttacaggc 544441 atacaacttt ggttctggat ttatagacta tgtcaaaaag aatggcggga aatacacaaa 544501 gaaattagca cttgatttca gccgattgca agcttttaaa atgggctgga aaagctacgg 544561 tgacccaagt tatgttgacc atgtcatgag gtatgtgaaa ggctctgata aaaatgtgaa 544621 gcctgtgaaa ggctctatgg atttctatga aacggtcatg aaagaagctt tgaaatatga 544681 agggcaaccg tatgcctggg gaggttcaaa cccggaaact ggatttgatt gttctggcct 544741 tgttcagtgg tcttttgcga aagctggaat cactcttcct agaacagcac aagaacaaca 544801 tggggcaacc aagaaaataa gtgaaaaaga agcgactgcg ggtgacttag tgttctttgg 544861 cggcacatac gaaggaaaag ccattactca cgtcggcatc tatgtaggca atggcagaat 544921 gtttaattca aatgacagtg gaatccaata ttctgatctg aaatcaggtt actggagaga 544981 tcaccttgta tcttttggac gcattaaata actaggagtg aaaatatgaa aacacatatt 545041 gcatgggctt cagcttgttt attattagtc atgttaactg gatttttcac gattggacag 545101 caaacgtata agattgaaaa gttaaaagat aaaaatgaag ttttgagcga aaaaattaag 545161 gaattgaacc atatagaatc aacaagtagc gcttcggaaa ataaggcatt ttttgaagcg 545221 ttttttaatt actccgacat agatatacga tatgaaacag ttaagaagca cacaactgga 545281 aaagggtttg attatgcatt cccttctcgt tctgatcaaa agcacacagt cagcgtgcaa 545341 agtgaattac tatcactaga gagttattca aagccgttag atgagtctca tgaattgttt 545401 ttaaacattg ttgaagtcgc cacaactgca aattcagtca ctacgaatca agtgttaatt 545461 gtacaaacga ctatgaaaaa agaaaaggat ggttggttag tcgataatgt gcaggttaag 545521 ggaaatggat aaaaggtgga aaagatcaat ttgtttgttt atactaaata ttgaaaaagg 545581 aggtaatgtt tattttgaaa aaccttttta ttttccttag tttgatgatg atgtttgttt 545641 taactgcatg tggtggaagc aagtatgatg atgcgattga tgatgtaatt agccaatata 545701 aagagcataa aggaaatgac acagagataa atattaaaag agagaatgcg attgttagag 545761 tctatgaagg gggcaaatat attcagtttg cattttatat gccggataac tcttcacgtg 545821 aattaacaac atttaagtat tatgaaaaat ttggagataa atatgaaaag atgactgata 545881 tgccggggaa tggggaaaat gatcgtctgg ggttatcaaa gaaaacacca gactatgaag 545941 aagtaaaagg agaagagaca gagttagagg agtaaaccgt gtgtttactc ctcttttagt 546001 tttattgaca ttggtaaaac agagataggg taagaactta gctaattaag aatgaaaatt 546061 ataaggttta taagttggaa actaaatcaa atatgtcttc taagaataga tttatgggta 546121 aaagttgttt ttacactatt ggtgctacta gcagtggcat ttaagttatt ttaatttcgt 546181 attaaattta gcctttatcc tttcccattt tttatcttct aatgtgagat catacatacg 546241 gagtattttt tcttttaaat taaataagtc tattggttcc tccaaggaga atgctttttt 546301 atttttatca attactcctt ttatttcgcc cttaaaacca gggaggatga aagtagagca 546361 gttattgcta ttcacccaag tagcccccat ttcattaagg cagtatacgc tatcatagta 546421 attatcggat aacatataaa agacatatgc acccttaaaa agatgttttt ttagatattc 546481 gaaaatatct tcatctccag gaataccatg ataaggtgaa gaagtgtata ttatatcttc 546541 agaagacact cctatatcct ctagtaattc aacgaaagca ttacatacaa ttttgtcttt 546601 tgaggagtgg ctaataaata tttttttctc taattctcta ttttgatcac ttgaaaagtg 546661 agttatgctg cttttttcag tctcatctac tacaggcaat tcatctaaaa atttttttat 546721 tttattttct gtttcatgat gttcaaactc attaaaaaca aattcatttt tatatatttc 546781 attgcggttt cgtgcatacc aagtcttaag ttgttctagt gaataacgaa ttaactcaat 546841 atcatttgat tcaagagatg ttcgaaattg atcaataata tttgtgagta caggctcgcg 546901 agagtaatct agaagtactc ctataattcc attagcctca aattttaatt tttttaatgt 546961 gtccattaga tttcctccga cctaatttaa tccattgttt gtaaacattt catatctaat 547021 tatataacat agactcctat tctaactact tattttaaag cagtctggat tgtttgggta 547081 attcataaaa aaataaaaga aagaaggagg aatagagttt ttcttttttt tgtttgcaat 547141 gttactgtca agtcgcaaaa gaattgctat gaccgaaaaa aaaccgcaaa ggaatagata 547201 taaggtacct ttttgcaatt catctttgta aaataaaggt tattctgaca taatacaatt 547261 aatgtaaaaa ttcgcacaat tttatgtaag gatgggggaa ttttcttgcg gggtgttttc 547321 ttagataaag ataaaattcc gtacgactta gtcacgaaaa agttaaatga atggtataca 547381 tcaataaaaa atgatcaagt tgagcaagcc gagattataa aaacagaagt agagaaagaa 547441 ttgttaaaca tggaagaaaa tcaagatgcc ctgttatatt atcaactatt agaatttaga 547501 catgagataa tgctgagtta tatgaaatct aaggaaatag aagatctcaa taatgcttat 547561 gagactataa aagaaattga gaagcaaggg caattaactg gcatgttgga atactatttt 547621 tactttttta agggtatgta cgagtttagg cgtaaagaat taatttcagc gataagtgct 547681 tatcgaatag ctgaatcaaa gttgtcagaa gttgaggatg aaatagagaa agcagagttt 547741 tttttcaaag tgtcctatgt atattattat atgaaacaaa catacttctc catgaattat 547801 gcaaatcgtg cactcaaaat atttagagag tatgaagaat atgctgtcca gactgtgcgt 547861 tgtcaattta ttgtagcagg aaacttgatc gattcattgg aatatgaaag agccttggaa 547921 caatttttga agtctttgga aatttccaag gaaagtaaca tagagcattt aattgcaatg 547981 tcacatatga atattgggat ttgttatgat gaattgaaag aatataagaa ggcttcacaa 548041 catttaattt tagcgttaga aatttttgaa aaatcaaaac atagtttctt aacaaagact 548101 ttattcactc taacctatgt agaagcaaaa caacaaaatt ataatgttgc tttgatatac 548161 tttaggaaag ggcgatttat tgccgataaa agtgatgata aggaatactc agcgaaattc 548221 aaaatattag agggattatt tttttctgat ggtgagactc aattaataaa gaatgcattt 548281 tcatatctgg cttcgagaaa aatgtttgct gatgttgaaa atttttcgat tgaagtcgct 548341 gattattttc atgaacaagg aaatttaatg ctctctaatg aatattatcg tatgagtatt 548401 gaagcaagac gaaaaattaa aaaaggggag attattgatg aaaatcagcc ggattctatt 548461 ggcagcagtg attttaagta gtgtattttc aataacttat ttgcaaagtg atcataatac 548521 tgaaattaaa gttgctgcag atcgggtagg ggcatagctt agataattgg aaaagaggaa 548581 aaaagcttaa tcttttttcg aaggttaagc tttttctttt atttataaaa agtgaactaa 548641 ctatcagaaa gaaattatat taaattttat ttttttgttt aaaaagtaga ttatataaag 548701 gcaagctagg tgggggaaaa tatgtttaaa aaagaaaaag tcacagaata catttggact 548761 atactaatac caacaatcat cacttttatc attagttggg ttgggtctta ttacaatggt 548821 acttcgacag ttagtattgg acaacctaca aaagtttccg gtcagtatat cacgccaata 548881 aatataagtc cctatcatga tattaaggaa ttaagaataa cttttccgca aaaactagat 548941 gtaaaacaaa ttagttcaaa tgagcctata aatgtaaaat cagataagaa caatatagga 549001 gttgaaagta attccacttt tgagattgcg aaaatcgttg aaaataatag cgttcagttg 549061 ctaattacaa cacaaaaaaa gttaaacgat aaggaaatta gaattgataa aaatggaaat 549121 aacatttctg taaattatga atctcagatt gttaatcctg caaaaaaaca attaatcaat 549181 cttataatta cgtcatctat ttattttata atgcttaata tactagcatt gattatgaac 549241 aaaagatggg ataagtatta tgcaaaaatg aaaaatgaaa tcaaagaatt tgaggataat 549301 gcaaaagatc ttgataaaaa atcaaagaag aaaagcgagg aattatcgga gctgcgaaag 549361 accttgaacc aagcgtttga ggaaactgat aggataaaat atcatgagaa gaaaaaacaa 549421 atcctcctct tagctaagtt aaacgattat aaaaaagaac taaccttttg gagaaataca 549481 ataagaaaag ttctttatga acttcctgat ggagataaaa aagcagataa actaataggg 549541 acagttacat catctttaaa aacgtacggt acagtcgaaa aaaacgagca tgattatgaa 549601 agtttaaaag tagcagctgc cttactaaat gattctgata agagatcgta atgtactgga 549661 ttttaataaa ctattagaaa gaagattagc tgcaaacatc agaacgacca aacaatggtg 549721 gtatgtttat agagtttagt tgttgaaaag ggcgaactat gagtttgctg cccatttact 549781 gcccagaata aataacaaat catgaaaatc agtgtaaata aaataactta atgctataaa 549841 taaaggcttt tgtaaataaa gatatgattt tactaggttg agggcctagt gggtgaataa 549901 cccgtggagg ttcaagtcct ctcggccgca tctcaataat accaagggtt taaccacctt 549961 tggtattatt tttttgtgtg gaaaatacgg ctatgggaga agacttgctc accaaaactc 550021 accagttact taaagtaagt catccaaacg gtcggcggtt ccttctgttt attaggaaaa 550081 agatatccgt tcattgtaaa agaaacgaac catgtcctat tcgttcaaaa aaactaaagg 550141 gtgatacata ttatacatga ttaatatgta tcaccctttt ctttcttgtt caacaatcgc 550201 gcttgaggag aacataagct aatacaactg actcgatttc taaagttgct ccattctttt 550261 tttaaacaac tcatccacaa cctgttttaa aatctcgtac gactgaattt ccttgctcaa 550321 ttcgtaaata ttagataaca caattaattc atctgcgtga tacatttgtt ggaaatcaat 550381 tagttcgcga cgaattgttt ctcgatcacc catgattgta taccccagtc gactgtggag 550441 aatttctaat tcaaactgtg ataacgattc taggaagttt tcagtgggtg gaataagctt 550501 acttaaatta tttgtataaa tatcaatata cacctgcaaa tgacttgcag aaataaaaga 550561 tgcctcgtct atagattctg ctgcaatcac attaatgcaa gcgatcacat aaggttcttg 550621 taaataagaa gacggttgga aattttctcg ataaatagag agcgcttctt ccatcgaatg 550681 gggtgaaaat tgagcgccaa atgcataggg taaaccaagc tttgcagcaa tttccgctga 550741 atccgttgag gatcctaaca caaaaacagg cacatgcgtt ccaatacccg gataagcgcg 550801 aacctcaccc tgtacactct tatccccgac aaaacgcaaa atatcattta cttctctttc 550861 aaagaaaaac actccattat ggttggaacg acgaatcaca tcggccgttt tttgatccgt 550921 tccgggtgcg cgtcctaatg ccaaatctac acgatttgga tataatgttt caagtgttcc 550981 aaattgctcc gctacgatta atggggaatg atttggcaac ataatacccc ctgaacctac 551041 gcgaatgtct tttgtatttg ctaatatatg ttgtacaatt gatacggttg ctgcacttgc 551101 ataagcgtcg tgattatgat gctctgcaaa ccaaatccgt ttatagccca tattatctac 551161 agctttagct aatgacactg cagaatcaat cccttgtttc attgtttctc cttgtcttaa 551221 tggagcaact gataaaacag atatatcaaa ttttttcata atttcacctc taaaataatg 551281 aacttataca agatcaatgg aaaaaacatt ttgaaaaatt gtttcatatt aaatggtgtc 551341 cattcctctt tgatttgcat gcaaataaat atatactttc tcaaacgatc aatacatagg 551401 caaaataaag ttatttcaca atttcacttt acttttaaag ttttaagcaa acataaaaaa 551461 atgttcagtg aacaaaatat gtaaaataca tcttattttt cagaaaggat acaagaaaat 551521 gattgatgaa atagataaaa aaatacttga tgagctgtct aaaaatagtc gccttacaat 551581 gaaaaaatta ggggaaaaag tacatctcac tgcaccagca accgcatcaa gagtagtaaa 551641 gttaatagac aatggcataa taaaaggatg tagtatcgaa gtgaatcaag tgaaattagg 551701 cttctctata catgcttttc ttaatattta tatcgaaaaa atccatcatc aaccctattt 551761 agcttttata gaaacacaag ataactatgt aataaacaat tataaagtta gtggagacgg 551821 ttgctatttg cttgaatgta aatttccttc aaacgaggta ttagatcaat ttttaaatga 551881 cttaaataaa catgcaaact ataaagtgtc gattgttatt ggtaaatagt taactttata 551941 aaacggagat gtgcggtcat ataacatgat atatatgctc taaaaaagcc ctaggttgga 552001 tatggaattt accaagctgg ggccttttta tacattataa taacaagcgc attattcatc 552061 agacattaat gaagtattat aatgcttttt tacttcctta atagacaaat aaagctgata 552121 gtttccatac ttcaataaat cattcagaag gtgatttaaa acttcttgtg aatgaaccgt 552181 taccttcaga agataacatg catctcccga aacacgatga gcttcgctaa tttcattacg 552241 agtagcaata aatttcaata aatcatcatg catatatgca ttcatgaaaa agaagacaaa 552301 ggctgtaaaa gaaaacccca tcttcaattc atcaaccaca atcgaatatg ctttaatgat 552361 accgttatcc tccatttttt tgatgcgatt gcctaccgct tgtcctgtca tatgaatttt 552421 ttcaccgatt tctttccatt gtatccgagc atttttattt aataattgga gaatttgaaa 552481 atcaattgaa tcaatttgca tagtaactcc tttcacagtg aaaaagtttt acaaaatagt 552541 atttcatgag accatcgaaa attcaatgga aattatatat ccttatacag tataaaaatt 552601 ttaagaggtg aaaaaatgac aacagcttta ttagtgattg atattcaaaa tgattacttt 552661 ccaaatggga agatggcttt aacaaaccca gagaaagcag cacaaaatgc ggctaaacta 552721 ctttcacact ttagaaacac aggcgcacct gtctttcatg tacagcatat cacagaaggt 552781 aacatcgctc attttttcca tccaaataca gaaggtgtcg aaattcatga gtcagtacgt 552841 ccattagaga aagagacagt cattgtaaaa catatgccga atagcttttt caatacagat 552901 ttaaatggaa agctacaaga agaaggggtt aaagaattag ttgtttgcgg tatgatgtcc 552961 catatgtgta ttgatgcaac agttcgttct gcagttgaac atggttatgt atgccaagtg 553021 gtagaagatg cttgcgcaac aacaacattg caaattgaag ataaaatcgt tcctgctgag 553081 catgtccatt acgcatttat ggccgcatta aatggtgtct atgcaacagt aaaaaccaca 553141 gaggcatttt taaaataaaa gaatttcctg cgcgaacata acgtctttct tttcacaaga 553201 aagatgattc aacaacttaa aaaaggatgt tcagaaaaat acttctggac atcctttatt 553261 cattatcttt tattgttttt cagtatcatt attcccatct gataaaagat caagatgtcc 553321 tgtttttgat ccatagtaag accatataca gggattgttt ttgccataaa tatagatatt 553381 gatgaaggtt tacataaagc acctaattgc ttgatttact ttaatgttag atccctcaat 553441 aactccattc tcttctaatt tctctactct agctgtagct gctgggcatg ttaaatgtac 553501 tctctcccag atctttcatt gaattcggct attatacata atttctctat aattttttat 553561 ctgtttgatc tatttgaacg ttaattcctt tcgaaaataa agtcaaagag ttaaaacact 553621 tttttttatc tatgtattcg aacactgctg atattataca cttaactctg tcgatctaag 553681 acaaataaaa aaagaaagtg agttgtaaat atgaatatta cacaaattcg aaatgcaaca 553741 attgttgtaa aatacgcaaa taaaaaattt ttgatagatc ctatgttagc agagaaaggt 553801 acgtacgcta ctttccctga aacgatcaga caagatttat ttaatccttt ggtgagtttg 553861 ccaacatcaa ttgataacat tctggatggc gtagatgcgg taattgttac tcatctacac 553921 ctagatcact ttgatgatgt ggcaaaaaac gtattgccaa aaaacatcaa aatgtttgtt 553981 caaaatgaag cagatgcaaa agaagtaaaa gcaagtggtt tcaaaaatgt agaagtgcta 554041 catcaagaca ctgtttttga agggatccaa ttagtaaaaa caaaaggtga acatggcaga 554101 ggggaagagt tattaaactt aatgggtgat gtttgtggat tagtattcaa gcacccaagt 554161 gaaaaagttt tatatgtagc tggggataca gtttggtatg atgctatcga agacgagatt 554221 catacacatc aaccagaaat cattgtggtt aatggtggag acaatcaaag attagattta 554281 ggttcactca tcatgggaaa agaagacatc tatgaagttc acaaggctgc tcctcatgct 554341 aagattatat ctgttcatat ggaagctgtt aaccattgga cactatctag agaagaatta 554401 aaaaacttta gtaaagaaaa aggattctca agtaatattt tagtgccaga agatggcgag 554461 tcttacacat tttaatatga acaccgacaa ataaatagaa gaagctcata attataaaaa 554521 ctaatcatga gcttcttcta ataatgaata ttttaaattt taaatatatc gaaaatccta 554581 aatatacgga ataacaaaaa tggaatgttc caatgatgac aaaaaaactt gaaaagcaac 554641 aaagatgtgt cgttaggagg tagaattcat ggtaatgaca aaaaaagata caaatatatc 554701 aacacagcag cctctttggt tacaaggtta tattgattca ccagaaaaac aaaaccaact 554761 ttataaaaaa acattaaaaa tcttgatttt ttcacaaata tttgggggag caggacttgg 554821 agctgggata acagttgggg cgcttcttgc acaagatatg ataggatcgg aaaatgtagc 554881 aggaattcca actgccctct ttacttttgg atctgccgta gctgccctgc ttataggagc 554941 atcctcacaa cgttttggtc gcagagctgg acttgcaggt ggtttcctta taggcggatt 555001 aggtgctata ggtgtgataa tcgcggcttt aattaacagc gttgccctat tatttgtttc 555061 tcttcttatt tatggagcag gtatggcttc taatcttcaa gttcggtatg ctgggacaga 555121 ccttgcaaat gagaaacaac gggcaactgc tgcaagtatg gccttagttt ctactacttt 555181 aggagctgta gtaggtccta acttagttaa tacaatgggg gaatttgcag attcaattgg 555241 tgttcccaat ttagctggtc cgtttattat gtcaggagca gcttttataa ttgctggaat 555301 tattctctta atttttcttc gtccagatcc gctgtttgta tcaacagcta ttgcgaatgc 555361 tgagaaaaaa gacgataaag tacaaatagg aggaagtcta aaaaatcctg ctatagacaa 555421 aaaaggaata atggtaggag ctgtcattat gattttagct caactaatca tgacagctat 555481 tatgacaatg acaccggttc acatgggtca tcacggtcat ggtttaagcg aagtgggatt 555541 agttatagga ctccatattg cagcgatgta tcttccttca ccattgactg gtttattagt 555601 agataagttt ggtcgcacaa ctatggctat tgcttcaggt gccacacttc ttgccgctgg 555661 gttggtggca gctattgcac cggcagactc attatcattg ctaatcctag cactagtatt 555721 actaggggta ggttggaact ttggtttact aacgggaact gcccttatta tagattcaac 555781 acatccatct ctacgtgcaa aaacacaggg aacattcgat gttttattag cactatcagg 555841 agcagcaggt ggagccttgt caggaatggt tgttgcacat tctagttata caatactatc 555901 aatttctgga gccgttttat cattgttact cattccagta gttatttggt attttagaag 555961 gattcaggaa aaagcataag cttatataac tgtctttgaa gaacctaagt agacattact 556021 ttaccggaac ctcctttttc tatttattat agtaaggagt tgacatggca ttagtggcat 556081 gtgtataact acacaattat ttgggattca gagagcatgt aatgaacgga agagataatt 556141 atttatcact tttattattg tacggtgttc ttgtggcatt aagttcagtc aattttggtc 556201 taactgtttt ctttttgttt tcatcacctc tccatattat taacaaacac gaaaaggatt 556261 ttaatgaaaa taaaatgatt agcgtatgta tctctaattt tcaaaatgaa tgaatagtcc 556321 tttttaagat ttacacactt attctccaag gaaaaatgac tcaatttttc gattttttat 556381 gtaaatcaaa aaagaatcat gttagagtag gtgtgctgaa aataattcaa aaaattattt 556441 tgcgatatga ttaaagtaat attgccagag agtttcaatt ggacaaaatt gtaagtgttt 556501 aatacactgg ggctgcaatc aaatatgcac ctggaatcaa ttgctaaacg ggggagttta 556561 tatgaacaac aagaaaaata tctttgatat tgttatgtac attattttcg gtgtgttaag 556621 tctttttcta gttgcaaaaa ctgattatgg cactggagtt ttagtgtttg ttgcaatttt 556681 atacctcgct gttattgctt ataaaattaa gcaagtattt agtaattcag attcttaagg 556741 tgtaacacaa ggaggatttc aattgagaaa gaaaagagtt attacttgtg ttatggctgc 556801 atcattgact ttaggctcac ttttacctgc aggttacgct tctgcaaagg aggactctaa 556861 gacaacccct tcttacgaag aactagctct acattacaaa atgaaaagtg aaaagatttc 556921 atcgaacggg aaattagttg aaattgagta tgtgagtgga aatgaaactc acaaagttca 556981 gatgaacgga aataatcata ctgtaaaagt cgatggcata gaacaaaaag gtttaaactt 557041 tgagtatgat gaaaatgttg ctaaaagaac aaattatgaa aacaataatt tgaaatcaaa 557101 tgaattcaca acacaggctg caaaacctaa aaagggatac cattatgtgg ggactttatc 557161 tgggcataca aaagcagcta aaaatgcgtt atcagttaca atgtcattag tcggtattgt 557221 ccctggcttg ggatggggga gtaaggctgc cactatttta ttctcttatt gggcaaaaga 557281 acaaatccct gatgcgtatt ataaatatga tttatacgaa aaaggagcaa tgactgatag 557341 ttggtatcag tatgctacag ttcaattttt tgaagataaa gctcataaaa agaaaatggg 557401 caaaccttgg acaagtactc ctgcaaaagt agatttacct aatagctaat tttaaaatca 557461 ctttgtcttt ataaaggaca aagtgatttt ttgttataca gaagtaaaat ccctcgtctg 557521 aggaatcttg gaaaaaactt ggttcaattt tgatataaca tgtttttttc ttgctaattt 557581 agtttttcta tgtatcgcta cacattctaa ataataagat attagccgga cggttgatgc 557641 caagctcaaa agtttatatg gaagtcaaag cataaaaaag ggtgttacaa cgtgtagtct 557701 tctttttatt ttgccaacgt aacaagtgtg aaagtaatga tttgtaggat cagttaagaa 557761 aggtttaaga ttagatattg aaaaatttta tatattttca ataaaatact ggtactataa 557821 taaatgtata cagattgtat ggagatgtaa ttaattaaaa aggagttttt aattgcgttg 557881 gagtaaatgg ttcaatgttt tttgtatagt agcattggga tcaatatatg gttataaatt 557941 atttactaac caagaagtca gtactactcg tttaataata gcttctgtaa ttgtgttgtg 558001 gaatattgtt ggacttttta gcaaagaatc agtaaaacaa gcacagcaag caaattaaaa 558061 gtcataaagt tgggaaagaa ggatgttact tatgtagtat ccttctttat tattccttga 558121 aaaatgaaac aaattggaga ttacagctta tataatcaat tgaagtcgtt gattattttc 558181 atgaacagga gatttaatgc tttctgatga aatattatcg tatgaatgtt gcaagaggaa 558241 acgttactca aagattacag ggatgtgatg aacactcctc tttatcgcac tcacctgacc 558301 ccaaattgtt ggggaagggc aggtacggaa gatagagtat tttttcttcg taacaaatcg 558361 aaaaggttgg ataataaaaa acttataatc taaggcggta tatagttgtg aaaaaggcgt 558421 tatttcttat attagaccag tatgcagatt gggaaggtgt ttacttagca tctgcattaa 558481 atcaaagaga agattggtcg gttcacactg tttctttaga ccctattgta agctcaatag 558541 gtggttttaa aacatctgtc gattacataa tagggttaga acctgcaaat tttaatttgc 558601 tagttatgat tggcggggat tcctggagta atgacaataa aaaactatta cattttgtaa 558661 aaactgcatt tcaaaaaaac attccaatag cagcgatatg cggtgcagtg gattttttgg 558721 cgaagaatgg tttgctgaat aatcatagcc atacaggtaa ttttgtttac ttatggaaag 558781 attacaaaca atataaaccg attagcagtt ttgtagagaa acaagcagta agagataaaa 558841 atttggttac tgctaatgga actgccccta ttgaatttac taatttaatt ttagagatga 558901 ttgattttga tactcctgag aacatagaga aaatgatgta tatgaatcgt tatggttttt 558961 atcatttttg tgataaatat ggaaatccat ttgttgatta atttgctgga aatgattttc 559021 ccgaataggg ggctttgcga ttgagttgaa tttcctaata aagcaaagaa agatgatttg 559081 aggtcaagtt taacaaataa tgccatcaat attaatttgc agttatttcc gattcctgat 559141 ataataaaga agaattattt ttgttcggtg taaaggatag tatgaagatt gacttttcgt 559201 cttgatgata ctttgggcaa ggatagtata tactgtgtgg ttacacacta ggaggcaaca 559261 aaaatggaac aaggtacagt taaatggttt aatgcagaaa aaggttttgg ctttatcgaa 559321 cgcgaaaatg gagacgatgt attcgtacac ttttctgcaa tccaaagtga cggattcaaa 559381 tctttagacg aaggtcaaaa agtatcgttt gacgttgagc aaggtgctcg tggagctcaa 559441 gctgctaacg ttcaaaaagc ttaatcttca atcgtttata caaacaggct ctttatatag 559501 ggcctgtttt tttatgtcta tatcatactc aataaaaaac cctactcaac gttcgagtag 559561 ggagatgcta caaggtaata gaaaaagatt taaaacttca aaggtttgtt tacagtataa 559621 catactggat tgacaatatg cggaatgtat ataaattatt taatgttttg ttcaaatata 559681 gataactgac tctttttttc actaacctgt tcgttcattt aagtaagatt agatgaatta 559741 taaaaatggt ttcatctaaa tgttatcaac tcgcatatct cttttatgag aagaagataa 559801 acaattatta ttcaatgttg cagtggatat aagaaattct taaaaataat gaggagatcg 559861 attgtttttt tctcctggaa ataatcactt agagatacct aaaacaatga aagccctacc 559921 tctcttccat ccttacggct ccttgtccgt gccagtgtga atcaggatac taaaaaaagt 559981 gactatttta ttgagttttt tggtaaaact tcaatcttcg cagaagaaat gtaaataata 560041 aaaatggatt agaatgtagg aataacaaaa gaggtcgtta atgttctaaa cataagttgg 560101 agaagatttg cttttcatca taatattccg aaatatcttt tgggatgtat ctaaccaaaa 560161 ctttttattt gtttttcagt gattccttta attacttcca gttcactaat caaaaattca 560221 tatgcattat ccagcatttt tttttcgctt gcattaagtg ctttttcttt cttcatacgc 560281 attaaatcac gtacaacttc agcaccttct tgtatttcac ctgtttttat tttgtccgtg 560341 tttattttgt acctttgctt ccatggcagt aacctatcgg attctccatg ctgaaaaatg 560401 tgcataatgt gttttaatgc aagtatatcg gtaactggtc gtatattcga actcaatatt 560461 ttactcgttg gaatcataac tgtcatatta ctgattgaca ttcttatgac ataatactgt 560521 tgtttttcct ctaagaattc tttttcttct atggcttcaa ttatacctgc tccgtgcatt 560581 ggataaacaa tgttatcgcc aatttgaaac atatcatcca cctccatata tggtatcctt 560641 cttaagatta ccatatatgg aggtgtaata tcaaaatttt aataataaca tgatcgaatt 560701 tttgatgtca ataacttttt tgaaaaaaca gatcaagcaa aaacaatagg gaacgtgtcg 560761 gatttccaat caggaaaagg tcaattgatc cgtgtgagca gtttttcatt ggctcaatga 560821 cattacagaa atgatttgag tagataagaa agaacgatat tcgtgaaatg tcagctaaaa 560881 atatttaaag cacatgatta agttctaatt tctttaccga tttgatatgg ataacggccg 560941 acttacttaa tgatgcattt tcacttatct tgcaagcaga aaaaggtttg ttgataaaca 561001 tttagccacc aaattggcat tattatcagg gaaattgaca accttcaaat gggtattgag 561061 gcgagaagaa aaataaagaa aggagagatt ataaatgaag accagaacat aaagaagtaa 561121 aggggaaaga acaaggttaa ttgaaaagca aactatataa aatagtttgc ttttttttgt 561181 tatgacttca cttctttttc tttctcttta atgactaata aaacaccgct cagaattaaa 561241 aacgaaccta tccaaaatgt cccgcctatt tgttctccaa gcagaatcca tccgagtaag 561301 gttccaacca gaggctgaaa aaagaaaaag aggcctccac ttgaggcatt taataattgt 561361 aagccgtggt tccacaataa aaatgcacaa gctgttgaaa caattcccaa atacaaaagg 561421 ccacctagaa ttttagggtc aagcagtagt ggcgtaaaaa tcgtgctagg ggagtaccat 561481 taacagggac tccatttatt aatagaataa actttatgaa ttcatttttt tgtatgataa 561541 tggcgtcata ttcatcgctt gttgaaattt acttatgaaa taactggtac tgttaaatcc 561601 aacttgataa gacacttctg tcacattgga ttcagggtgt tgcagtaata ataagctttt 561661 ttgaattcta taatccatta cataacgtaa tggcgtctta ttcagcattc gtttaaaata 561721 acggcagcat tcagaacggc tcagttggcc agcttttgca atgtcctcta atgtgatttt 561781 ttcaacataa tggagatgga tccagtttaa catttgtttc attcgatgac tttttatcat 561841 ttcagattga tcgtactcta attgaaaacc attaacgacc aggtttttcc acattaacgt 561901 taattgcatc gtaatgtcaa tctcatagag cgatgtcttt tgttgaatca attgatttat 561961 ttttttaaca gcatctagaa tattttttgc ccactgttga tttccagcca aaaataaata 562021 gggcaaattg gttgaaaaca tatagggctg aacatagctt gaatacagtt cctgagataa 562081 aacgaaatgg ggtgacacat tcaagcaaat atacgtacaa tccgagcctt ccttttcttc 562141 ggccatgtgc aggtagccgc tattgataaa taatccatcc ccttcgtgaa cctctatttt 562201 ttcttcattt atttgaaaga gagctatccc ttttagtatc aaaacaaatt ggatttcatc 562261 atgccaatga agcggaatat agccatttat attttgattg atcgttgtct tgtagcaggc 562321 aactggcaat tctaccgttc ggtgctctgt taattctttt aaattttgat cgatcacaaa 562381 attcttcatt ctgacttcac acctcaatat atttatattt tttcattcaa tttgagtatt 562441 ttttatcatg ttttgcattt attataacac tattattata tttattagtg aggagtcatg 562501 tatgaatact tccaatagaa gaatgggatt gttctatgtt atcacagggg cgacatgttg 562561 ggggattgga ggcacagtag ccaaaaaact ttttcaagaa tatcaaattg atgtcaattg 562621 gcttgtaacg acacgcttgc ttacggctgg aatgttactt ttaatgctgc aactgttcag 562681 aaaggatcgt tcccaggtta ttgaggtgtg gaaacacaaa gcgtcggctg gccagcttct 562741 aatttttggc ctattgggaa tgctagctgt gcagtacaca tatatggcat ccattcaaca 562801 tgggaatgct gccgttgcta cgttattgca atatttatcc ccagtaatcg tcattatcta 562861 cacgctgttg cgaaaacaaa cggttcttac caaacaagat atcataactg ttgtacttgc 562921 tttagtgggt tgcttttttt tgttaacaaa tggttcaatg tctcaacttt cagtgccggc 562981 agctgcagta gtatggggag ttttatcagg attcgcggca gctttttata ctttgtatgc 563041 cgttggttta ttaaataaat ttgattctct tgtcgttgta ggttgggcta tgattattgg 563101 cggttttgca ttgggtttta tccatccgcc atggcaactg gattttcaac gattaactgc 563161 tgaggcgtat gcatatatct tattcgtgat attatttgga acaatgattg cgttctggtt 563221 cttcataaaa agcttggaaa gcctctctcc aaaagaaaca agcctactag gcagtctaga 563281 gcctctatca gctgttgtaa caactgtcgt ttggttaaaa gcgccatttg gttcttttca 563341 atggattggt gctatttgta ttatagggat aactttaata ttggctttac ataaagagcc 563401 ttctatggag agtgaaaaat cgatattaaa gattaggaat catgcaaatc gggatatata 563461 ggggcttttt ttgcttacat gaccggtccg gcaatgaaaa acactggtgg agtttgagcc 563521 ctctcggcag tatcaaaaat accaagggtt ttgacgccct aggtattttt tcttcaagaa 563581 ccttcaattt ttcttctctg attgaaaaac gtattacttt tttgtgattg gtatccaaat 563641 ttcactttta aaagatggtg atgttacatc cttatgctcg ttccacaata tttctggacc 563701 ttctatttgt tcgtaatttg acgatggaaa ccattcggaa taaatgcgtc cccatacttc 563761 ttgcagtgta tccggaaatg gcccgattga ttcgaataca gcccatgttg aggcaggaac 563821 ttcaagccgt gagaagttat ctggacaccg tttcgttgtg gctgcgccaa tatagtgatc 563881 gagctctccg ttttcctctg tccgaccttc agaaaaattc gtggatgcac taatgaggcc 563941 tgatggtgct acattagata gctcttttag tttatttatt gctttttcat ctaaactttc 564001 ccacatagat gcaatttccg gattaattcc tttgaaaata ataggaactc tttttttaat 564061 gccaacgatg cgaaatgcct ctttttcttc aatacggtag ttcatttcat ttcctccttt 564121 aattgttagc tggaaggtca ttcgtggata agctttaagg gaatggccat taaatctggc 564181 ttttgatggg tttatgccat gtaaattttg gaatgcccgt gcaaaagaat ctggtgagtt 564241 ataaccgtac tttattgcaa tatcaatcac ttttacattg ctgtctttca gttcaaaagc 564301 tgcaagagta agacgtctgc gacgaatata ttccgataat gaaatacctg caaggaagga 564361 aaacatcctt ttaaaatgat attcagagca gaaagcaagc tttgctgcct cttgaaaatc 564421 aatatcatta gtgaggtttt cttcaatata ctttaacgcc ctattcatac ttttaagcaa 564481 atccatttat ttggcctcct ttaaccaaag aataacagga gtgaaatgta tttatccgac 564541 attctgtgca cagttttgca ggatgactta tatgaaataa agtaagtgat tcacttgtat 564601 ttgtacaggt tttattgaag catgctgttc ataaaaaggc atcaataaaa gaaagttata 564661 attgtcttat aaacggcaca ttcatataat tgagtgaaaa aggatgcgta tcatgcctat 564721 caattctttt gaaaattatc cgatgagctg gaagccatcg attgataaag ctgaaaagcc 564781 tatttataaa gcacttgcag ggcaattgga acaggatatt ttaaacggag ttttattacc 564841 tggaacaaaa cttcctccac agcgagaatt ggccgattat ctagatttaa atgtgagtac 564901 gatttcaaaa gcatttaaag tgtgtgagtt aaaagggctg ctgagtgcga ctgtagggag 564961 cggcacattt gtatcgtatg atgcgttgtc gaatgcgtat ttacttgagg atactaagcc 565021 gacacattta attgaaatgg gagcaatact tccagatcac gcttcatatg agcccttgtt 565081 ataccaactg aaaaacatgg ttcatgagga ggattatgaa aaatggttta gctatggccg 565141 ggcaggtgaa agcctttggc aaaaagatgc agctgtaaag ctcatccaaa gaggcggatt 565201 tgaaacatcc gttgatcaca ttttatttgc aaatggaggg caaaatgcga ttgcagcgac 565261 attggcgagt ctttgtaagc ctggagatcg catcggagtt gaccatcata cgtaccctgg 565321 attaaaaact gttgcatcat tgcttagtgt gcaaatcgta ccgataaaat cagaaaacga 565381 tgaaatgagt ccggagtcac ttgaatatgc gtgtaaaaac gaaaatatta aaggtttgta 565441 tttaatcccg gattatcata atccgacgac ttcctttatg tctgttgaga atcgaagaat 565501 ggttgcagac attgtaaaga aatataatct gtttgttatt gaggatgcat cgtaccatct 565561 tctcaacaaa aatccgcttc cggcactcgc ctcattcgca ccgcaacagg ttattcatat 565621 tgcaagttta tcaaaatcgt tagcgccagg cctgcgtttg gcttatgtag cagtgccgag 565681 acaatataag gagccaatat caaaggcgct ttataattta aatataactg tttccccgct 565741 attagctgaa cttactgctc gcacgattgt atcaaatcaa tttgaagtct taattgagag 565801 tcatcgtgaa caaaccattc gcagaaatca actcgtaaac cgatatgttg cgggatatac 565861 atgtttaggt gttgaaacag gcatttttcg ttggttgttg ttaccgggta aaatgtctgg 565921 tgccgaattt gaagaattgg ctgctcgact tggcgtgcaa gtgtatgcgg ctgaacgctt 565981 tgtagtggga aatagttgtc ctgaaagggc tgtaagggtt tctgtctgtg caccaaaaac 566041 acttgaagag cttgaacaag gattaatgat cctgagacgt ttgctagacg atcttaccta 566101 atattgtttg ccatacaatt atgacattgt atggcttttt tgtgcgtgtt atgatgatcc 566161 acatctagag ggaggtttat acaaaattgg cttttagaaa ggaaggtcag atgatgttag 566221 acaaggacag cgtaaaagca atagatgttc aaactgcttc attacagagc tacatcagtt 566281 caccagaaaa acaaaaatcg ttatacaagc gtacactatt cgttgtgagt atctcacaaa 566341 tttttggcgg tgcggggctg gcggcaggag tgactgtcgg tgcgcttatt gcacagcaaa 566401 tgcttggcac tgatgcgttt gctggtttgc cttctgcttt atttacttta gggtcagcag 566461 gatctgcatt aattgttgga agactttctc aacgttatgg ccgtcgaaca ggtctttcag 566521 ctggctttat gattggcgga cttggagcaa taggcgttat tatggcagca atcataaata 566581 gtattttctt gttatttatt tcgttgctta tttacggtgc aggtacagcc actaatttac 566641 aggcccgtta tgcaggtaca gacttagcaa atcataagca gcgagcgact gctgttagta 566701 taaccatggt ttttactaca tttggcgcag tggcaggtcc aagcttagtg aatgtgatgg 566761 gggatttcgc tctttctatt ggtgttccat cacttgctgg ccctttcatt ttagccgcag 566821 cagcatatat gttagcaggt gtggtccttt tcattatgct tcgtccagat ccattagtta 566881 tagcaagaac aatagaagcg gcaaatgaag agcctggtga taaaggacat ttggcggcaa 566941 ctgagcatac agaaaacaaa aaagggataa tcgttggggc aacggttatg gttcttaccc 567001 aaatagtaat ggtagctatt atgacaatga caccggttca tatgagacat catgggcatg 567061 acttgggtgc agtcggtctt gttattggtt ttcatatagg tgctatgtat ctcccttcac 567121 ttgttacagg tgttcttgta gataggttgg gacgtaccgc aatggctatt tcctctggaa 567181 caacgttgct tttggcaggt gtaatagcag catttgctcc gggagaatct atgattcttc 567241 tcgtcattgc tctttcttta ctgggattag ggtggaattt tggtttgata agcgggactg 567301 cccttattgt agattcaact gatactgcca cacgagctaa aacgcagggg acagtggatg 567361 ttctgattgc gttgtcagga gctgctggcg gagcattatc tggaatgatt gtggcaggtt 567421 caagttacct cgcattatca cttattggag ggattttgtc cttattactc attccggtgg 567481 tggtatggtc taggggccgc taaagggtag gattgtttaa tttacattaa tttgttatat 567541 tgttagataa agtatattgc agcatctaat attctaacga actatagttg ctccattaaa 567601 tctattataa agatttgacc aggattcctt atagctgtgt cactcactgc atattcttta 567661 attgaatcac ataaaatggt tatcggattt gaaaaaggca ggattactcg ctttaggtaa 567721 aggagtcata acgttgttaa aaaggttttc tcttgttatt gttacactaa tgatgtctat 567781 cgttgttgtt ttagcggctg ctaaagagtc gcctggagat catgtcatct catttgatga 567841 acctattatc ttgatgatct caattggaat cgttgtattt ttattgatcc ctccattagt 567901 catgtccttt tttggcaatt tggttgtaag aataatatct ggtgtatacc aatgttttat 567961 cgttttcact tttctggggc tcattccaat tggatttctt attcccaatg gctttttgac 568021 aattctagtt tctattgcag gaactttagt cagtatagct agtgttgccg taaccttatg 568081 cattggcaag aataaaaaag atatataatc atcgaattgt tattttttca gattgtcagt 568141 gaaataatta tacaaaaaga gaaggcttgt gggccttctt tttttgttgt tgcatcatcc 568201 ccactttgag cttaatctat tgaataataa gagaaggaac ctatagaaga ataaaataaa 568261 taccgagatg tcaaaaataa aactggactt cattattgtg aattcacgta aatgtaaaaa 568321 gattggaaag aggggaattc cttcatgaca aatagcagaa caaatccgaa ggttgatgaa 568381 tttttaagta aagcgaaaaa gtggaaggaa gaatttgaga agttgagaac catcattctt 568441 gactgtgagc tgactgaaga ttttaagtgg atgcatcctt gttacacata tcataataaa 568501 aatattgttt taatacatgg gtttaaagaa tattgcgcgc ttctgttcca caaaggcgtc 568561 ttattacagg atacagatgg aattctcatt caacaaacgg agaatgtaca ggcggcgcgc 568621 cagattcggt ttacaaatgt tcaggaaata aatgagctag aaaacatttt gaaagcctat 568681 attcacgaag ccattgaagt tgaaaaagcc ggtttgaaag tggatgttaa caaaaatatt 568741 gaattgaaca ttcctgaaga acttcaaaat aaattcgatg aaatccctgc attgaaaatt 568801 gcttttgaag ctttgacccc gggacggcaa agagcgtaca ctctttattt ttctcaagcc 568861 aaacaatcca aaacccgaga atcgagagtc gaaaaatatg tgcaaaaaat tctcgatgga 568921 aagggattaa aggattaggc acgccaaggt tcaggctaaa ggaatagcat catagcgtaa 568981 taagatcatt tctatagaag aaaaacaagc atagtaagat gcttgttttt tcttaggaca 569041 acattcactt actgctgaaa tgcttctaac attgtatgcc actagacagc gttataaaat 569101 attaatgcaa cacctagaaa tctatccaat gaaatagctc aatggtatgg ctcattacat 569161 ttagaatgcc taggagaact aatagaaccg gaagattttt agcaagttac tacactccaa 569221 actttgtttt tgtattaata taccttatta accattgttt ttagtcaggt gcagacaaac 569281 gaatactgat taatgaatca tcatgatatc aatgagccgc ttgatttttt catcgtcgcc 569341 tgtatcaacg tacactgttt ttctgttttt tatgatactc tcagtcactt cccgcatgac 569401 gcctttttct atatcatcag cggaatccca gcgtaaaggc acattatata catgaattgt 569461 gccatcccca ttgccatgat aagtgactga tccatccact aaacgagaac ctgccaactg 569521 ggtcacattt tctggatagc tggcacttgt atcatcatta ggattaattg gctcgccagc 569581 cgcaatatgt cgaacattta attcatctat ctcttgatta ggtccaagtt gaagccaaac 569641 tctggcatat tcaatttttt ccgaagagta tgctgccaat acattgtctt ctttgctttt 569701 ctcttctgct gaagaggtat catttgcagc ttttgttgcg gattcttctg attctgttat 569761 tggctccgct tcatccttgc gtattttggt gctctcttca ggctcagtgt gtttttcgtc 569821 agtttgcaca gcagaagctt gatttgaagg ttgttgtgct tctccatcct tactgtccgt 569881 acatccagca agcaaaatca taagcagcag ggcagtattg caataacata tctttctgcg 569941 tttcttcatt ttttcattcc tctctattaa ttcaggtcag cttcatatat aagtttatgt 570001 atctaaatat taccatggaa tagataggat gatattgaaa actgtttaag aagaggaaac 570061 gatcttgaat agcatcgcga aaacctaaga atcttaagaa gttttgcccc tttttcttca 570121 ggtattgaat gtaaagtggg atataaatgc aaacaaaaac gaaatgcctt atccacctcg 570181 tgtcatggca gaaaaagtgg gggatttatt agagcggatt tgataatggc ggcaggtaaa 570241 tgggtgttga cttatatgtc taagcgggag actcaagtct gctcgatcgc atacaaaata 570301 ccaagggcca gcaacccttg gtatttttat accttcatgc atttttgaag tttatgctta 570361 aaggtctgcc ttactttgca aatcgccgag ctgctgcaac gcacatgata acggcgatat 570421 tcactgctac gagtgcccag cccactttct cgtgcagaat cactgaggca agcagcagtc 570481 caaaaaaagg ctggagaagc tggagctgcc caaccgctgc aattccccct tgggcaagac 570541 ctcgatacca gaacacgaag ccaatcagca tgctgaataa ggatacatat gcaagactga 570601 gcagtgcggg aacgccgatc gccgaccatg agtccggcgt aaaaaagaac gacaatggca 570661 gcataagagg aagcgacaga acgagtgccc atgagatcac ctgccaattc cccagacgcc 570721 gtgaaagttt ggccccttct gcataaccaa gaccgcatac gacaatagaa gccagcatgt 570781 acgcgtcgcc aagcggggat gaacctcccc cctgaatgag ggcgaaacct gctactaaca 570841 agctgccggc agctgagaaa atccagaaga cggggcgagg gcgttcaccc ccgcgcagta 570901 cgccgaagac tgccgttgcg agtggaagaa gtccaatgaa gacaatggcg tgtgcggatg 570961 tgacatgctg aagcgctaaa gctgtcagca acgggaaacc aatcactacg ccgaacgcta 571021 ccactaacaa tgaaatgaga tctcttttgg caggatgctg ctgccggaag atgagaagga 571081 gacctcccgc cagtacacca gctatcgcag cacggcaaac tgtgagaaat aacggatcga 571141 agtctgacac agccaaacgg gtcgcaggca gcgagccgct gaaaatgagt acgcctataa 571201 aaccatttat ccagccattt gttgttttgt tcattataat cactccacat atctttcttg 571261 ttcattgtct gtattttctt aacaaaacca gcagctaagg attacaatga ctataaactg 571321 gaattggcct tttataaaca gccagttttc ataaaaaaat gcataccagt taggagaaca 571381 acgcgcaaat ggatatcacg ccttttttga atagaactct ggatattccg ctttatcagc 571441 agctttatcg gtattttaaa gaaaatatgc atcggggccg tattcaaaaa ggaatgaagc 571501 ttccttcaaa aagactcctg gcgaatcagc tttccatcag ccaaacgact gtagaacgtg 571561 cctatgaaca gctcgctgct gaaggttata ttgtgagcaa gccaagaagc gggtggtttg 571621 ctgattatca tgattctgat tttgcttatg atagaatgcc aagcacaaca cccattcaac 571681 aagaagcaga agaaaataaa caatggattg attttcatta tgggaatgta gattcttctt 571741 acttcccttt ttccgcatgg cgaaaaagca tggtcaatag cttagaccaa tatggacacg 571801 agctttatcg gccgggacat gttttaggag agtttgagct gagaacactc attgcagagt 571861 acctgtatca atctcggggg gttcattgcg gccctgaaca agtgattata ggtgccggga 571921 accctattct gctgcaaatc ttgtgccaag tttttgagcc gaatatttct atagggtatg 571981 aggatcctgg ttatccaaga gcacgcaaga tttttgaagc caaccgcatg aatattgttc 572041 ctataccagt cgatgatgag ggaatctgta tacagaagat caaagaacag cagccaaacc 572101 ttgtatatgt cacaccttcc catcaattta cgctgggaac cataatgaca ataaacagaa 572161 gaattcagct gctcaaatgg gcggccgaaa atcaatcctt tatcatagag gatgattatg 572221 acggggaatt taggtacaca ggacagccgg ttccttctct gcaagggctt gatcagcata 572281 accgtgtcat ttatatgggc actttttcta agtctctttt gccctcgctg cgtatcagct 572341 atatgattct tccttcgcct cttttaaaaa agggtcatga aatcacgtcc ttatataagc 572401 agacagtgtc ctgccacagt cagctaaccc tagctgaatt tataaaaaat ggagagtggc 572461 aaaaacacat caacagaatg agaaaacttt accgcaaaaa aagagccatt gtattagagg 572521 cagtgcaaag ggaattagga gagcatgtca gaatccgcgg agaaaactct gggcttcgta 572581 tcttacttga cgtttatttg ccatttggtg aaaaagagtt aattgagaag gcgaaaaaac 572641 atggagtaaa aatttatcct gtttctcttt cttatcaaca tcatcctcct acaaaaacgg 572701 tctcgctcgg gtttgcaggg gtttctgaat ccgacataag agaaggcata aaaaaactga 572761 aggctgcctg gaagatatga gggagctttc agtttagcaa aacggccaag tgacgactaa 572821 gtgttgagag ctgttcaata ttttttaagt atatgatgag tgcctgcagt ccaggccacg 572881 atacgtctgt ttagcgaaaa acagaatttt ttatttgctc ctcacagtgc taaaataaac 572941 aaaatagaca attgaaaaaa tagaggtgta agaatgaagt tagatgagtt tacaattggc 573001 caggtcttca aaacgaaatc attaaaagta tcaaaagatg atattatgcg gtttgcgggt 573061 gaatttgacc ctcagtatat gcatgtagat gaagaaaaag cgagtaaagg cagatttaat 573121 ggaattatcg cttccggcat acaaacactg gccatatctt ttaaactttg gattgaagaa 573181 ggtttctatg gagacgatat tatagccgga acagagatga atcatatgac attcataaaa 573241 cccgtatatc cggatgatga attgtttaca attgttgagg ttcttgataa gcagccaaag 573301 agaaatgaat tgggaatact cacagtattg ctatctactt ataatcaaaa agaagtaaaa 573361 gtgtttgaag gtgagttatc tgtattgatc aaacgataac tcagaaagcc cgcttttcgc 573421 gggctcgatt gaagcagatg ggtgaaagat gttagcgggt ttcctttgaa aaataagagg 573481 ttaaaacatc ataaacaata ggcaaagaag taaatccctc atcttctaga aaatgacctc 573541 cgtgctgaac ttcatataac gcagcatcaa tttgttgtgc cagatccttg ctgaatgaaa 573601 aaggcacaat ttggtcgtcc ttagaagcaa tgacagcacg gtgcttcgcg gactcgatga 573661 ttttttgatg atcaaacgat ccctgtgtaa attcatctaa catctgtaaa gtgggcaatg 573721 atttggcaaa gccggaaaca agtatgattc cgccaagctg ttttcgtaat tgaagatgtt 573781 ccaaaaatct caaaatggcg gggcaaccta agctgtgcgc aaccaaatac gtattttcat 573841 gtaaagtgtg ctgatataaa gagagtgtat ccagccaatc ctcaagtctt ggctggagcg 573901 gattaggcat gtttaaaatg tctgcttgga ccccatctgc gagcagacgt tttttcagcc 573961 aagggaacca atgatttgtt gaggaggctc tgtagccatg aatgatatag acttgttttg 574021 tcattatttc ctcctaagaa atattttcat tcagtataaa attcctctca ttgggaaaca 574081 agtacgcact tttttgtaag tagctttaca tatgaggccc tccttgtgcc attccccact 574141 tacacatctc atctatgagg ggatacaaag atcgccctct gtcagataac gaatactcta 574201 ctttcagtgg ggtgtgagaa acctcagacc gatgaataag gccgtcagtt tgcaattcct 574261 taagctgtgc gcttaacatt ttatgggtga tgaagggcat agcccttttc agctcgccgt 574321 atctcatcgt tttttcacac cctaactcat agagaattct cattttccat ttgcccccta 574381 taagagataa ggtgtattca aatggggctt gtttactgcg gcacaggcta ttcattgtaa 574441 tcaaacctcc ttttttaagt atcatatcag aataaattag gattttcggt gttgaagttt 574501 gagggcgatt cacgatctga agtgaaaggg gccgcttgct caacaggcgg cacggtacat 574561 gaatgttcta agtcaaagag ggttacctta ctgttagtta ctttatttaa aaaaacgcat 574621 gtttttagct gaaaatatct attatggtat atttaaatat aaagaaatat ttgagaaatg 574681 aggaatggta tgaatacacc caaaaaacat aagaaattta aagcgaaaat gattctccaa 574741 atcatcatgg ttatcattgg aggaatcata gcggcatatg gactagaaac agtgctcatt 574801 ccaaacagtg tatctgatgg aggggtgacg ggtcttagca tcgttggttc acagctattc 574861 aacttgccgc tggggatttt gattgctgtg atcaacattc catttgtctg gttaggatat 574921 aagcaaattg ggaaaagctt tgcattatta tcaattatcg gaatcgtatc gcttgccgcg 574981 gggacaagct ttttccacca cacacccgct atcatagaag gagataccct gttaattacc 575041 gttgtcggcg ggattatcct tggattcgga atggggctgg cgctgcgtaa tggcggcgca 575101 ttagatggaa ttgacatgct tgctgtgctg ctatcccgaa aactgccatt cggaacgagc 575161 gatctcattc tattcttaaa cctatttgtg tttatttttg tttccacagt atttggctta 575221 caaggggcat tgctttcagt cattgcttac tacattgcat ccaaagtgat tcatgttgtg 575281 gaggaaggct taagcggctc taaaaccttt caaattatta caacccaacc tgaattaatg 575341 gtagagacaa tacgtgatca attaggccga agcgccacat ataaagaagc ttacgggggt 575401 ttttcccacg agaaatttaa agaaatcaca tgtgtcatca accgtttaga agaaaccaaa 575461 ctaaaggaaa ttattaatga tattgataaa actgcctttg ttaccgtgta tgatgtagct 575521 gaagtgaagg gcagcaattt tagaaatctt aatcatcact aaaaaataga atgacctttt 575581 taaccgtaac tgacatgccg cgggtaattt aatcaaaaac acttttttga ggcttgtggg 575641 tgaataaccg gtgaaggtct gaatcacaga aataccaagg gcgtcaaaac ccttggtatt 575701 ttttctggtt attagatttt atcttcagct ttacgtgctg cttcgagctt atcaatcctg 575761 tctttatatt tttctcccca gtccttcatg tgcaggataa caggttctaa tgttcttcca 575821 aactcagtta aagagtattc gacttttgga gggacctgtt tataaacctc gcggtgaatc 575881 acgccatccc gttccaattc tcttaattgt agcgtgagca tacgctgggt aatttttggg 575941 tatagttttc gaaactcatt aaacctcttt ttaccgtcaa tgagatgata aagaagaatg 576001 cctttccact tacctccgat gatatctaat gttgtctcca ccggacatcc ttcaaagtca 576061 tcagaagaat aatcaatgcc gagtttacga tttctcaagc tgttcactcc taatagtata 576121 ctttttgata ctatatacat tcaatgtgcg tactttttat attttaatat acatcatata 576181 atgatgtcac atctaaggaa tgaaaggaat ggatcatatg aaaacactcg tactcgttgt 576241 acatccgaat atagaatcct ctcgtatcaa taaaaagtgg aaagaagccg ttttaagtga 576301 accagatgta actgtccatg atctttatga aaaatatcgc gatcaaccaa ttgatgtgga 576361 atttgaacaa cagcagctcc tggcccatga ccgtatcgtt tttcagtttc cattatactg 576421 gtacagcagc ccaccgcttt taaaacagtg gtttgatgaa gtgtttacgt ttggctgggc 576481 tcatggtccc ggcggaaata aattgaaggg gaaagagtgg gtaactgcca tgtccatcgg 576541 ttcacctgaa cactcttatc aagccggcgg atataacttg ttttcgataa gcgagctgac 576601 aaaaccgttc caagcatctg cccatttagt aggcatgacc tatctgcctt cctttgccga 576661 atatcgcgcc aatacaatca gtgaccaaga aattgccgaa agtgcgaatc ggtatgtaaa 576721 gcatattaca aatatagaat taaacccgaa ggttcgcctg caaaggtatt tgaaacagct 576781 ggagagtgtc gatttaacat aaagattgat ttttgaaaat cctgtactca ccaagcagga 576841 ttttttcttg ttcagcagag ggattttaac atatagcaaa aaaagaagaa gccaccaaaa 576901 ataagctatt tgcttggtcc tgactgctta tttttggtga aatacttatt tctctgtgat 576961 gaaataaagc aaagcgatga ccggaaaagc gattccaatc cataatgctg tactccatcc 577021 gcctgaggca tatgcccatc ctccaattga tgaccctatc gcaccgccta gaaagaagat 577081 cgccatgaat aatccgttta atcgactgcg aatttcaggc gccaacgaaa aaatagcacg 577141 ttgactgagc acaaggtttg cagatacacc catatctaac agaatagcag cggccactag 577201 aactgttata ccgacggggg agctgctctg aatcatgagc ggcagtaata aagagacaac 577261 gacaacaccg agagcgattc cagtggcaag cctggttaag cctcgatcag ccaggcggcc 577321 gcctattggt gcagtgactg cacccgcaat gcccaccaat gcgtagagtg ctattgcctt 577381 ctgagaaaaa tgaaaatcag gaccggacaa taataaagga acagttgtcc agaacaagct 577441 gaaagctcca aatacaaacg catgatagat ggcacggcgg cgtaagactg gagtcgtgcg 577501 cagcagcttc cacattgaac cgagtaaggc agtatagttt gtatttgctg ttggttttct 577561 ggcaggaagc acttttgata atacgatggc caggataaca cttaccacgg cggacaaagc 577621 gaatattgca ttccaccccc agatatcagc gactagacta gatatcggac gggaaagcat 577681 aataccgagt aataagccgc tcatgacatt gccaacaacc cggccgcgtg cagcgtctga 577741 tgcaaggtat gatgcaaatg gaacaagcac ttgggctgcg attgatccca atccgacgaa 577801 aaacgcagct gctaaaaaca gtgttccatg cttcacaaat gctgttagtg tcaaagccgc 577861 tgcgcttaga aggagcgata caacaataag ttttttgttt tcgataatat ctcctaaagg 577921 gacaaggaat agtaagccgg caacgtatcc gatttgggtg agtgtgacaa tcaatccagc 577981 accgcttgga gaaagtccaa ttgccttact aattaatccg accaagggtt gtgcatagta 578041 aagattagca acaatgatac cgcatgcagt tgcgagaaga agggttaaac tgggtgaaat 578101 cctctgacct gcttgtttgt ttccattagc catatgaatg aactcctttt taagtggttt 578161 tttgagtgta atcatgactt ctcacaagtg attttataaa ctgaacgttc agtttcgtcg 578221 attaataaaa ataatatact aaacgttcag ttttgtaaat ggatttctgt tttctttttt 578281 tattcaattt aagtatactg aacgtatagt ttatattgcg ggaaggaatg atttatgtgc 578341 agagtaaacg agggcggccg cgtgatgaag gaacgcataa ggcgattctc tctgcagcct 578401 atgacctatt gctggaaaaa ggcttcgatg cggtgacagt cgataaaatt gccgagcgtg 578461 cgaaagtgag taaagcaacg atttataaat ggtggtctaa caaggctgcc gttatcatgg 578521 acagctttct ttcgaccgcg acggacaggc tgcctgtgcc tgatacaggg tcgtcagtac 578581 aagatatagt aacccacgcc acgaatttag ctaggttttt gacaagccgg gaaggaaccg 578641 ttattaagga attaataggt gcagggcagt tggatgaaaa attggcagaa gaatatcgca 578701 cgcgattttt ccagcctcgc cgcctccaag cgaaaggcct tctagaaaag ggaattcaga 578761 aaggtgaatt gagagagaat cttgatattg aagtaagcat agatctcatt tacggaccaa 578821 ttttctatcg tctgcttata acaggggatg aggtgaatga ttcctatgtg cgtgatttgg 578881 tgatgaatgc gtttaaggga gttcaagcta cctctgctac agagagtatg tagctgataa 578941 gaactgcaaa agctgcggat tatatgacaa attggttcca tcgtacagtg aaatataaga 579001 tttttgttgc tgagcggaat catcgaggga aaagttctct tatcggatgt cgaaaaagaa 579061 gtcattcaat cgtgaataca taacatcata ttattacatt ccttttcatc gattggaaca 579121 agggttctat acttcaatgg aataccgcaa agttggagta tttaaacaac aggggaaaat 579181 cgatggccat tatgtaggtg tcatggcaat ggaaaaaata cttgcaatgt aaacaggcct 579241 ctaaagagac ctgtttttta atatccagat gattgtctag tttcagcttg ggctctatga 579301 ccactcccat aactgaaata gtctaatatt tataccagaa gggattgttt atataaataa 579361 aagtttatat aatgacgggg gcgctaagga aacgcgggga gcgactcagg ttttcgtttc 579421 aaagttttga tccttaagat atacggagcg ctacatatgg aaacgtaaag gggaatgtat 579481 aatcatttgg cgtgtatata acgatttgct tatatattga tttgggaagg aggagctcat 579541 atgacgattg atgttgcggc gatgactcgt tgtttgaaaa cacttagtga tcaaactagg 579601 cttatcatga tgagattatt tcttgaacaa gaatattgtg tctgtcaatt ggttgatatg 579661 ttcgaaatga gccagcccgc cataagccag catttgcgga aattaaaaaa cgcaggtttt 579721 gtgaatgagg acagaagagg ccaatggcgt tattattcaa taaatggttc ctgtcctgag 579781 tttgatacat tgcaattgat cttacatcaa attgatcaag aggatgaatt gttaaaccat 579841 atcaaacaaa agaaaactca agcgtgttgc cagtaaggag gcattagatt gacatcaatg 579901 attttggcag tattcatctt tttattaact ctagtattgg tcatatggca gccgaaaaat 579961 ttatctatag ggtggtcagc ctgtggaggc gcagttttag ctctaatagc aggtgttgtc 580021 aattttcatg atgtgttaac tgtgacaggg attgtttgga atgcgacctt ggcttttgtg 580081 gccatcatac tgatatcgtt aattcttgat aatatcggtt tctttgaatg ggcagcgctt 580141 catatggcta aggctgcaaa aggatacggt gtgcggatgt tcgtttatgt atctctatta 580201 ggagctatcg tcgccgcgtt atttgcaaat gacggtgcag ctcttatatt gacaccaatc 580261 gtattagcga tggtcagagc attacatttt aatgaaaaat tagtttttcc ttttatcatt 580321 gccagcggat ttattgcgga taccacttcg cttccttttg tagtaagcaa tttggtcaac 580381 attgtttcag cggactattt tcatattacg tttattgatt atgcatccag aatggttgtc 580441 ccgtacctgt tttcgctgct ggcgagcatc attgtacttt accttttctt tagaaaaagc 580501 ataccaaaac gctatgatct gactgaggtt aaaaaacctg ttgaagcaat taaagatcaa 580561 aacatgttca gactgtcatg gtatatctta gggctgctgt taattggata ttttgcaagt 580621 gaattttttt ctatccctgt atcagtggta gcgggcagca ttgcaatcat tttcttaatc 580681 gctgcgcaaa agagtccggc cgtccataca aagaaagtgg tgaaagaggc gccatgggct 580741 atcgtattct tttcaattgg catgtacgtt gttgtgtatg gtgtccgaaa tgccggatta 580801 acggatgtcc tttcagatgt gattcaagcc gcagctgatc aaggattgtt tgctgggaca 580861 attggaatgg gctttattgc ggcgattctt tcttccatta tgaataactt gccgactgtt 580921 atgattgacg cattggccat tgccggtaca gatacacatg ggatgatgag agaagcgctt 580981 atttatgcaa atgtgatcgg ttcagattta gggcctaaaa taacaccgat tggttcctta 581041 gcgacattat tatggcttca tgttctttcg cacaaaggta tgaagatttc ctggggcacg 581101 tattttaaaa caggaattat cctcacgata cccactttat tgatcacact tgtcggcctg 581161 tatatttggc tgctgataat ccattcttgt ttctaaaagg acaaggtcac tatatcaagg 581221 aaaacaatgc actggtaact cttgccgcag ccaaatggct gaagggtggg ggagaaaata 581281 ccttggggct aagtggaatg tgtacagcgc aggaatcgaa gctcaaggat gacatcgagt 581341 gctgtcaaag caatgaaaga agcagggatt gatatttcaa atcaaacatc ggagaaattt 581401 gatgatccgg caaaagcaca cggaacagaa gaagtgtttc caaagggtcc gtgatgaaat 581461 tggtgaccgt ttaaaacagt ttgctgtaac tggggaataa agaatcgata tattcagcgt 581521 tttcttgggt tatataatac aatgtgttgt tcaacaggtg tctgcgagct gagtgcagac 581581 acctgttttt gtttttattt gtctgagatt cgtaacaggg aagttattta gctggtgaca 581641 gaggaaaatt gatttgtgaa cagaatcatg aaggagacgg tgttttaaag gagttgtctg 581701 ttttgcagga attaacaaaa aaaaaataca gtagcttaaa aacaatgttt gatgacaaat 581761 attgtcccac atttgtctat tcaatattag accaaaccat tccgggagct gtttatgcag 581821 atgatcaaac ctttcctaaa tcgtttttta taggaactga atcaggcatt tattttattg 581881 cgggagacca agggaatcgg gattttcatg atttcattgc aggatattat gaagaacaag 581941 tgaaatcatc aaaacgattt accttgtttt cttccagtga tacatgggat agcgtactga 582001 aacccatact gaaagatgac ttaaaccaaa tgagaagagc tgcattttct tatcaaccaa 582061 aatctttcaa aaagactttg caactgccaa aggggcttgt attgaaaaga attgacgaag 582121 acatcatttc acatagcaca gcgtttaaca gcgcgtatta tgaggagtat tggaattctg 582181 tctcacagtt tgcttcaaaa ggttttggat ttgccgtatt acatggcaat cacgtagtaa 582241 gtgagtgtac ctctatattt ttagggcata atcgagcgga aatggatatc tatacacttg 582301 aagaatatag aggactgggg ttagcttatt gcgtagcaaa taggtttata gcgttttgta 582361 tggaaaatgg gattgttcct agctgggatt gtgatatttg caacaattcg tccattgcat 582421 tagcagctaa actagggttt aagacggtaa cggaatacac tatttactac tctggctaac 582481 cttaatgaaa gaaccttaaa aggagatacc aaccgatgtt ggtatctttt ttgttttaga 582541 gtttttttac ccttttagca gaaaaatggg tgatgaaaat cttattcatt ttatttactt 582601 ttaggtaggt aaaacatacc ccgccaactg taaccactcc gcctagcaga gagagcagtg 582661 tgggtatctc gccgatccag agccaagata tgatcaaggc taaagccggt gtaacataaa 582721 gtgaaagggt tgcttctgaa gcaccgacga atgaagtgac atatgctagt gcgaagtaag 582781 gaataaccgt cggcaataat cctaagtaaa cgatagacaa agttgcgctt attgaagcgt 582841 tcatcatctc ttcgcctaag cctggcagaa acacaagcat aggtattgtt ccgccccaaa 582901 tggtgaatgt aacgaatgga ataaaaccat atttttttat atagcgggct tgaaaaacga 582961 aataaatact ctccgaaaat gctgccagca ggatgaccaa gataccgctc attgaatatg 583021 taaagtctcc cgccccaaat gcaatcaata atacacccaa taaactgatc atagagccaa 583081 gccatttcgt aaatccaaaa tgctctttat aaaacaggcg ggatagcatg gctgagaaga 583141 tcggtgccgt agtaacgagt aagcttgcaa ctccggcact aactgttttt tcaccgatgt 583201 tcagcaaaat gtgatagaat gcaaatccta aaaaccctaa aagaaaaatg gcaggaatgt 583261 ctttcaagtc gggtaggcgc atctgagtca aaacagcaaa aagcaataat gccatagagc 583321 cgattaacaa acgaaataaa gcaaggtgtt ctggcgtgta cccttcaagt cctgcgcgaa 583381 ttcccggaaa agcagatgcc cataaaccaa tcatgagact atgagatatc attatttgaa 583441 ctgttttctt tcgcattcct ctcactcctc tttacaaaaa ccaaccagtt atttaatgtg 583501 tttctatact aataaagatt tgatgatatg gcttcaacca gttcaataga ttttgaccca 583561 accaatttat tttaaggaga ccgattctat gagctttcca gaagaaaaaa agatgaaaaa 583621 gctccctaag tacagacaaa tcgttcattt tattaaagag aaaataggaa atggagagtg 583681 gccgattgga agcaagattc caagccagcg cacgcttgca aaagattttc aggtaaatcg 583741 gagcacagtg attacagcgt tagaggaatt gatggccgat gggctaatag aaggcacaat 583801 ggggaaaggc acagttgtta tcaacaacac atggacactg atggctaaga attctgctcc 583861 cgattgggat caatatgtca cctctggcat tcagatgcca agccgaaaaa tcgttcaaga 583921 gataaatcaa tcagaatcaa atacagacct tatacagctc agtaaaggtg aactttcagc 583981 tgagattttt cctttggctg ttatgaaaga gatgatgggg aaggtatctc aacacatgga 584041 ggcattcgga tatgaagaac caaaaggtta cttacctttg agggaggcat taagcaacta 584101 tttaaaaacc attggaatca acgtctcatc ttcttccatt ctgattgtct caggagcgtt 584161 gcaagccttg cagctgatat caatggggct gttacaaaga ggatcaaccg tttatcttga 584221 tcagccctcc tacctttatt cattacacgt atttcaatca gctggtatga agctgactgg 584281 acttcctatg gataatgaag gacttttgcc tgaaaatgtt catttaacaa gaggagagcg 584341 gggaagggct atcttatata caaatccatg ttttcacaat ccgactggta ttcttatgtc 584401 taaaaagcga cgggaagaaa tcctagcagt aagtgagaat acacagcttc ctattattga 584461 agatgacatt tatcgtgagt tatggatcga tgaaattccg ccatatccta ttaaaacaat 584521 tgataaaaat ggacacgtac tgtacatagg aagtttatcg aaaacattaa gcccaggttt 584581 gaggattgga tggatcgtcg gaccggaacc ggtgattgaa cgtttatctg acattaaaat 584641 gcaaacagat tacggatcca gttcgctatc ccagagagta gcggcagagt ggtttacttc 584701 cggccactac cagcagcatg tagaaaaggt taggcagcaa ttaaaggtga gaagagaatt 584761 ggccttgagt gctttagaaa ctcatttgaa agaagtggcg acatggaata tcccaaaagg 584821 agggtttttt gtctggataa aaatattgcc ttccatatca atgaaattac tttatactaa 584881 agccttatca aaagggattc tgatcaatct cggcagtatc tatgctcagg aaaaagggaa 584941 ttatattcgc ttatcatatg cttatgcatc tcttgaagac cttcaaaagg ggatttatga 585001 gttgggttta atgattaaag aattggcaag caggtaactt ttatatcctt aaatggatgt 585061 ttcactaaaa aagagatcaa gcctaatgat cgcttgatct gataataaca agggttacta 585121 gaatagacca aatcatggtt cggtcttaaa ataatcatgt ctctgaacga aaagtctttc 585181 cgacttctct tcctaaacca aagtagtgtc tgaaattata gataagcggg ctccatttgg 585241 aagggttgat atggttttcg tccagaatga tactttcctc ggcatgaaaa tgtagtgcct 585301 gcgtctctac aattgcgaat gacgattcat attctggaag ccgaatgtgt ttcacttcgg 585361 cttcgatttg gatagggcat tctttaattc gtgttggtga tactgttttt gattgtaaag 585421 gcgttaaccc tgctgcctcg tatttttctt ttttatatgt aaatccgatc tgcttcttta 585481 aaggcggtat actctttttt ccgctataag atgaaattct ttcaacgttt tcccataaat 585541 ccgggccagg caagtttatg acacactctt tgtgtctttc caaattgtcg atggcttttc 585601 ctcccagtcc tactccaagg attatataat gtccaagagc ccaagaagaa gacataggac 585661 taatattagt ggttccatcc tcattcaatg tggttagaag aaatgtcgag gtaccataat 585721 acatgatctt gggtttgatt tccttaaatc gacgagtgtc ttgttttttg atgtccaacg 585781 ttttttcctc cttgtcacgc ttacatttat attgtaaagg attaacattt caactatcat 585841 cgaaatatga atgtaaggag gaaaatcatg aatcctaata ttgcaaaaat ctcttcgttg 585901 ctatcagatc cctcgcgttc ttccattctt ctcagtctga tggatggaag gatacaccct 585961 gcgggagagc ttgcatatct cgctaacatt aaacctcaaa ctgcaagttt tcacctgaat 586021 aaattgcttg aagcaaagct gattagcgta gagaagcatg ggagacatcg gtattacaga 586081 ttggctgact cagatgctgc aaatgtgatc gaacaattgc ttcatattgc gcctaaagca 586141 aaagtcaaat ctttaaaaga gtcaaaagag aaaaaggact tgcatttcgc ccggacctgt 586201 tatgatcatt tggcaggtta tgtgggcgtg caaatggcac attcactagt tgagcagggg 586261 atgttaaaaa aagttgattt aaactttgag gtgacttcag agggtgcttt attcttttcg 586321 aagttaggca tcaatgaaga gcaacaacgg aataagagga gagcctttgc ccgctgctgt 586381 ttggattgga gtgaacggca gcatcatatt gcaggagcat taggaaacgc cctattggtg 586441 cgcatgttag aagaagaatg gatcgttcgt atgcctaaaa cgagagcgat taggattaca 586501 caaagcggga aaatcgcgtt tgaaaagcac ctaaacgtga agatttagga ttttgaagcg 586561 gaaacatcag atgatgaggc acgatatcta ggaggagtaa gatttgttct aatcttactc 586621 cttcttctta ttttgaagca gctcgattcc ccattgcaat agagatgcgg ttccaactgt 586681 ttatttgatt aatgatcaga acaaggtcaa catattgttc ctcatcataa tgttcccgca 586741 cccgatgata tagctcatca ggaacccttt tagatggaat gagcgtgatg tgttcagata 586801 gttcgagagc cgctttctct tcaggtgagt aaaaatcaca ttcattccaa gcatgtaaac 586861 agtaaattcg ctgttcagtt tctcccattt tgcgggcatc ggacgtatgc atatctatgc 586921 agaaggcaca gccgttcatt tgagagactc tgattttgat tagttctctc gtcgttcggt 586981 taattgagga ttgtttcgtg tatttctcca tatccatcat gattttcata ccttcaggtg 587041 caatctcata gtaggacact ctttgactca taaagcaaga ctcctttcca tagaatacct 587101 agattgtatc ccggtattga tcattttacc aatgtgcggt ttgaatgaca gctgtttcag 587161 cgtcttttgg aaagaagctt ctttgaataa aaataagggt agccagcaat gatgagtgga 587221 gctgctaatg caagcagtat ccatgagcct gattggctgt ctctagtgac tctaatgaat 587281 atataagtac cgatcagaaa atataataaa gcacctagaa accaatacat gttcattcct 587341 ctttttcctt gctttttggt tgcgcatttt tgtctgtcat atggcttaat cgatcagggt 587401 tctgattttt taataccttt tcggtccgga ttccttttct ctttaatgat aaaattgtga 587461 gatcaatcga tttcaatgat gatcattcct tcaatgaata gtaagttcct tatgatttta 587521 aaggtaaatt tgaaaagata aaacgtacat agaggcagaa cgttcatgta cgtttgggca 587581 atgatcactt gttggaaact ctaatgtttc cctgcacctg atattgttgt gttccttctc 587641 ttcctataaa atgattggat acatgtatgt ttgcacgttg aaatatgggt tcgattttca 587701 tgaatctcta ttcggtgaaa caggtaaagg aagtggataa ggtttgctta taaggaatcc 587761 ttttaaagat aaatattact cacatgatag gcgggcatta aacatgcttg cactcagagt 587821 gccgggcctg gcttttattc tcatgatcta tatagcctct atcgtgctgc aatttgtttc 587881 tgggggctgg tccattttat tgctttatgc gtttaccata ttaatcgcca tttttgcttt 587941 gcttcattgg cactcatatc gctgggttaa gaaaagagtg attctgtatt tcgcggtaca 588001 aggtttgatc acctttgcac ttgctaatct catgactggc ttctttatac ttgtgattat 588061 cggcctttat gcatttttaa ttggacaaat tataggaatg gcagacagaa gaaggacttt 588121 tctcattctt tatctattgc tgctgctggt cataaattcg gcgtatcacc ttcataaagg 588181 tgaagttttg cattttattg ttattgctgc gccgatcatg attgtcatca tcacttatgc 588241 cgcaacattt tttgcccaag tcgatgaaaa aataaaagct caattgactc ttgaaaggct 588301 ggagctggct catcagcagg tagaacagct gacgctgcag aacgaaagac agcggatggc 588361 ccgagactta cacgatacgc ttgctcaagg tcttgtcagt ttaaatatgc agctggatgc 588421 gattcatgtt catctcgcca aaggcaacac agagagagcg aaggaaatca tacaacaatc 588481 gatgaaaaga gtgaaaagca caatagctga tgcacgttca gctattgacg atctccgcag 588541 caaatcagaa gaaatcggtg ttttaaaaga aagaattacc tcgctaatgg atcattttat 588601 agagtcgaca ggcatggctt gtttattaga ttacagattg catcaggtgc tggatgtgcg 588661 tacagctgaa aactgttatt acatcattgg agaatgcatg acgaatgcgg caaagcatgc 588721 tgaggcgaaa acaatctgga tatccatttg ggatgatgaa aagggaaggc tccatttaac 588781 agttaaggat aacggcaagg gatttgatgt tgaaaaagga aagaaaaaga gaggacatta 588841 tgggcttctt ggcatacaag aacgcgtcag ggcaataaat ggccaattca atatcaagag 588901 tacaaaattg aaaggaacac aaattgagat cactgtacca attcagggag agatgcaaga 588961 tgaataaggt tttaatcgtt gatgaccatc ttgtcgtgag ggaaggtctg aagcttttaa 589021 ttgaaacgaa tgatcaatac accattatag gagaggcgga aaatggaaaa gtagcagtcc 589081 gtcttgcaga tgaattagaa ccggatatca ttctgatgga tttgtatatg ccggagatga 589141 gcgggttaga ggccattaaa caaataaaag aaaaacacga tacccccatc attattttga 589201 ctacatataa tgaagatcac ttaatgatcg aagggattga attaggagcg aaaggatatc 589261 tgttaaaaga tacgagttca gaaacccttt ttcacacaat ggatgcagcc atcagaggaa 589321 atgtgctatt gcagcctgat atccttaaac gtctgcaaga aatccaattt gagcggatga 589381 aaaagcagcg caatgagacg cagctgacag aaaaggaagt cattgttcta aaagcaattg 589441 ctaaaggtct taaaagcaaa gcgattgcct ttgatttggg cgtctctgag cgaacagtaa 589501 agtccagatt aacgtccatt tacaataaat taggcgcgaa ttcaagaact gaggcagtaa 589561 cgattgccat gcaaaaaggt attctgacaa tagacaacta aactgcatat ttgaaaattg 589621 cccaaacgta catgcccgaa tgtacgtttt tttcatttca ttgtcaacta caatgagaaa 589681 gaatgtgatc aagcaatgtg ttgaaaggag attatcatgt caaaaatgtt atatacatta 589741 ggaggatggg ttgctcgcaa tcgcataaaa gcaatatgtg cgtggatcgt tgtgttagtt 589801 gctgcgatag gccttgcagt gaccttgaaa ccaagttttt ctgaggatat gtccatacct 589861 gacacacctt cggaaaaagc gatggatgtg attcaaaaag aatttcctca tggtcctgat 589921 aaagggagca tacgggttat tttcggtgct ggtgatgggg agaaacttac tgggaagcca 589981 gcaaaaaaag caatagaaga tacgttcaaa gaaatcagta aagatgattc tgttgactcg 590041 attgcaagtc cttttgtgac agggacaatc gcgaaagatg gcacagttgc ctatgctgat 590101 atccagtata aatcatcagc agatgatata aaggattact ctatcaaaca cttaaaagac 590161 agtttgaaaa tggctgatga tgaaggattg caaactgagc taagcggaga tgtaccggga 590221 gcggagatgg agataggcgg tgtctctgaa attgtcggca ttatcttggc ttttgtcgtt 590281 ttagccatta cattcggttc tttattaata gcaggtttgc cgattttaac tgcactgatt 590341 ggtttaggtg taagtattgg actggttttg attgggacac aagtatttga tattgcttct 590401 gtcagtcttt cattagccgg aatgattggc cttgctgttg gtattgatta tgctttattt 590461 atttttacga aacaccgcca gtttttaggc gaaggcatac aaaagaatga atcaattgcg 590521 agagccgtgg gaacagcggg aagtgcagtg gtttttgccg gacttactgt tatcgttgca 590581 ctttgcggat taactgtcgt taacattcct tttatgtctg cgatggggct gacagcaggg 590641 cttagtgtac tgatggctgt tttggcttcc atcacacttg tgcctgcggt cttatcgatt 590701 gcagggaagc ggatgattcc gaaatcaaac aagaaaatag aaaaacaaag cactgaaaca 590761 aatgtctggg gacgctttgt caccaaaaat cctatcatgc taagtgtatg cagcattctg 590821 attttgatcg tcattagtat cccatctatg catttggaac tgggcttgcc tgatgctggg 590881 atgaaagcta aggataatcc ggatcgccgg gcatatgact tgcttgccga aggctttgga 590941 gaaggattta atggccaatt aacaatcgta gcggatgcca caaatgctac agaaaataag 591001 gcggaggctt tcgcagatgc agtgaaagaa ataaagggct tagaccatgt agcaagtgtc 591061 actcctgcaa tgcctaataa agaagggaac tttgccatca ttacggtcgt tcctgaaaca 591121 ggtccaaatg atgtcacaac gaaagatttg gtacatgatg tacgcagttt atcagataaa 591181 aacggagtag atttgcttgt tactggatca actgcagtga atattgacat ttcagatcgc 591241 ctgaatgatg cgataccggt gtttgctgta cttattgttg gctttgcgtt tgtattgctg 591301 accatcgttt tccgttcgct gcttgtgccg cttgttgctg ttgcaggttt catgttgacg 591361 atgacagcca ctcttggaat ctgtgtattt gtcttgcaag acgggaatct catcgacttt 591421 ttcaaaatac ctgaaaaagg gccgatactc gcgttcctgc cgattttatc gattgggatt 591481 ctgttcgggt tagccatgga ttatcaagta ttccttgtca gcagaatgcg tgaagaatat 591541 gtaaaaacaa acaatccagt acaagccatt caggctggat taaaacacag tggtcctgtt 591601 gttacagcag ccggcttgat catgatcttc gtttttgcag gatttatctt tgcaggcgaa 591661 gcttctatta aagccaatgg gctggctctt tcctttggtg tactctttga tgcctttatt 591721 gtaagaatga cactgattcc aagtgtcatg aagctgatgg ggaatgcagc ctggtatttg 591781 ccgaaatggt tagacaagat tattccgaat gtggatatag aagggcatca actgacaaag 591841 gaaatacagc cggaaataga tcatgaacaa aagaaacaaa tcagtgtgta atagaaaaag 591901 cagatctttt atgatctgct cttttgctta tggtagtatt tagaagatga agtcggcagt 591961 taaaaggaga cgcttatggc gccatcactc attttcgata tggatggaac tttgtttcat 592021 attggcagaa gctgcatcat actagcaggc atcccaggag aagtgacatg attttttgac 592081 tttgcattca ctacttgatg ccaaggatct tgagaatcct tcttgaaaat aaaggatttt 592141 acaactgatc atataagaaa cctaaagaaa caagcacaca aaaccagctg cgggttttgt 592201 ccaagaaaaa tagagtccat aagagggact ctattttttg aagtgcccgg ctagaagcat 592261 attgcaggac tttatgaatg caaatcacta tcttataagc ccttaccgtg aaatgcctgt 592321 ttctgcattg aaaaaacgca ttacacgttc atttacgtaa gtgggttgtt ccatcgataa 592381 aacatgtccg gcatttttaa tgacttccgc ctcaatatct ggaacgaatg aagaggctcg 592441 gtgcagggct gagtggggat catagatgac ttcatgttca ccaagtaata ataggatagg 592501 aactcttgct gaacgtaatt cctcatcggt aaaaacatac ggaaatccgt cggcattagg 592561 atttggattt cttgatccat cctgccacat tacccctgcc ttaaactgct tcacaaaaat 592621 cgggtgcagc acattctgat cattcatcat ccaatttaag aatgtttcaa ctccatttga 592681 cgctgtaagg ccaagagcgt atttgtagaa atcgtgatga aatggcaaaa acgtttctgc 592741 cggactcagt atagctgcgc tttttactct ctcaggcata cgtaaaagga aattcatcgt 592801 atggagaccg ccaagcgaaa gtccgatcat gtgggacttt tcgatcccca gattgtcaaa 592861 cacatcaaga agccaattgg cgtaatccgt tcttgtaccg cttacattct caggaatact 592921 cttgttttta tcacctatga tatcaactgc ataagttctg tatttactgc tccaatcggc 592981 gatgttggga taccacatcg tcgagctgaa taatgctccg tggagtaata caagcggcgg 593041 ggcatcctct gggccgcttg caatcacatg tgtttgacca aaacgagtag atatatagaa 593101 tgatttacaa cggaccggcc aaagactaag gctttcatta taagtttgat aatagcggat 593161 accgttgtca cttaattcgg gaatactaga tgaatggttt gacatacaaa tgcccctccc 593221 aattttgttt aaatgaatgt gccgtttcgt gatggggaat ctgattttga tataacagac 593281 tttatttaca atataataca gttgttatta gacgtcaaat ccaagatgaa aaggaaaaaa 593341 acgattgaaa cagattattg aaaatcaata taacagaata ttaacctcct ttgtggagcc 593401 gcttcattaa aaccgcaatc caaatgcatg aatcacaaaa atcacaacag gagggatcag 593461 gagggaaggc agcagattca gtgttttgaa cttcttgatt ccaagaatgc ttagacctga 593521 actgaggatg agtatgcctc ccacaattgt gatttcatta ataaggtctg tattgattgc 593581 gctctccatt acttgtgcaa ataaatagat ggagccctgc caggaaaata atacaagtgc 593641 ggcagccgct attccaaaac caaaagttga agcgagcaca atggaggtga tcccatctaa 593701 catcccgttt gtcagaaggt atgtataatc tccatgcaaa gcggcttcaa cagggcctaa 593761 tattgacagc gaacctatac aaaataataa gaccgcagtt gataagccct ctgctaaatt 593821 gcttttagaa aatttgttca ccagcttgtt gaatcgtaat tctaaattga tgatctggcc 593881 tagcaaacct ccaatggcta aactcacgat gaatagaatg gggtatttac tatcaggcaa 593941 atgctgtgta atggcgttga tccccagtgc gaccgcagcg aatcccattg cctgcatcaa 594001 aatatcctgg tattcatctt taatgccttt tttgaatatc cccccgatta tgcttcctgc 594061 aatgatcatc actgtgttaa aaatcgttcc aaacataagc tttctcctcc aaaaatcatt 594121 cctgcataaa aaataaaccc tctagttagt agagagtcaa gggagatcaa aacatattca 594181 tgagattatt tgatgggcag caggatttca gtcacgtaat tatctaggtt attcgtaatg 594241 ccataatcaa tgagtgtgat ttcgattgag tcccctgcta cctcataatg atgttctttc 594301 atatatgcca gtaatttttt gtagtatggt tcggcttctg gatgtgaccc tttaaaccta 594361 atttgcagat attctcttga aggaaagatg atttctgaag aagttttttc attttcatct 594421 tcaagaatca taaatatact ggaatatttg tcaaactgtt ttgctttcac atttgctgca 594481 gaaatggata aaccaatctt gcctatgaat atatcttcgt ttacattcag gtgggttctc 594541 aattcagcta acgaatgttc gatatcatgg ccgagaacat attcatgctg caaataggcc 594601 acacgcattg cgggaagttt gatttttgaa atttgatgta acggcatgtt aacggcatct 594661 tctatatgtg tgatgcgtcg ggagatcttt cgttcaatgc gttccaattc tttcttcttg 594721 cgatcaattt caacctgctg gctttttagt aaatgaagaa gagtgtttgt attttgagag 594781 ttataaaaat caagaagctt attgattggc aggcctaggg ccctcaaata cttgatggta 594841 tccagccgct caaactgttg ggtagaataa tatctatagt tcgtttgctc atctttatat 594901 tccggtttca aaaggccgat ttcatcataa taccgaagag cagagatttt cacattgaat 594961 aactttgaca cttctccaat cgaaaaaaat tccttcattc taacaacctt tctgtcctat 595021 gattgatata cacacattat atagtacggc gagtactaaa ggtaaagttt gcagcataaa 595081 gaaaaaactc cttctaaaaa ggagcttttc attcttcgaa ataaggattt acatggatga 595141 gcacttcttc tacatctgaa aactgtcttt tgatttcatt tcgaatttcg cgggcaatgt 595201 cgtgtccctg cttaattgtc aaatcatgat ccaaagataa acggacatca agcaatttat 595261 agtggccatg ttctcgcgcg cggattctat caattcgttt tacctgatca cattgaaaaa 595321 taacagcttt atattcctct atcagctcgg gatcaacact cttttccatg agcacatcaa 595381 cagacggcct gattaattcc attgaaatct taaaaatgag gtaagcaacg attgcactgg 595441 caatggcatc ggcgtacaac agataggacc atccacggct gtttccgatg atagccaaca 595501 ggacgccgat aaaagcggca agagaggcaa cgatatcgcc tttatgatcg tacgcaatcg 595561 ctataatcgc tttgctgttc cattttttcc cttgctttat agaataacga tataagattt 595621 ccttagccac gtacgaaatc agagccgcaa acaatgcgct gtattgggga acgcttggcc 595681 ctttaacaaa ggacagaatc gcttctatga ggatataaac ggatacgatc actaagataa 595741 ttcctacaat cgcctcacta atgacttcag cttttccgtg accaaaagga tggtcttgat 595801 cgggcggttt attggaaatt ccgatcactg ccaagactgc aatcgaagca acgacatctg 595861 ccgcggaatg tattccgtct gcaaacacgg cttcactatc gcctaccagc ccaaaaaaga 595921 cctttcctgc cattaagatc agattggcga tcaatgcaat caaagcaact tttctgctta 595981 tttgttctct ttcacttgcc attttttcct cctataaaac tgcacaaaaa aataggagtg 596041 ctctatatac gctctccgta tcctttcctg tgtaatcact ttgtttatca taccaattca 596101 atttcgagtg ggtctatagc aacgttgttt cctgtttact aataaataag gtgacagaaa 596161 aaaagttgga gctatgctaa aaaggtcata cagcaaacaa atgagttctt atgtaacaac 596221 agtgatgatt cgctattaaa atgctgccgt cagtgaaaaa tttccaccta attttcaaaa 596281 acctattgac atgagaagat ctgtatttta ctattatctc atattcaaga tattttaatt 596341 tgagatattt ggtcggaaag atcagcgatc aagcgcaact ctaagtgttc aatcgttgtc 596401 agttctttta cacaatattc aatatgattt tttataacat aatatctcga attcgagata 596461 aaagggagtg tagcgtaatg gctgaattta ctcatttagt caatgaaaga cgatctgcaa 596521 gcaattttct ttcaggtcat ccaatcacaa aagaagatct caatgagatg tttgaattgg 596581 ttgcattggc accatcggct tttaatttgc agcatacaaa atatgtgacg gttcttgacc 596641 aggacgtaaa ggaaaagctg aagcaggccg caaacggaca atataaagtg gttagctctt 596701 ctgcggttct cttggtatta ggggataagc aggcatatca acaagcggcc gatatctatg 596761 aaggtttaaa ggtattgggg atattaaata agcaagagta tgaccacatg gtgcaagaca 596821 ccgtttcgtt ttatgaaaac aggggagaac aatttaagag agatgaggcg ataaggaatg 596881 cttcactttc tgcgatgatg tttatgctga gtgctaagga aaaaggctgg gatacctgcc 596941 cgatgatcgg ctttgatgcg gaagccgtaa aacggatttt gaacatagac gaccaatttg 597001 aggttgtcat gatgattacg attggaaaag aaaaaacaga gagcagaaga ccgcgcggct 597061 accggaagcc tgtgaatgag tttgttgagt atatgtaaaa ggagcggata aaaatggcta 597121 aaaaaacgat gggaattcat catattacag cgattgtcgg tcaccctcaa gagaacacag 597181 atttttacgc aggagtgctt gggcttcgtt tggtcaagca aactgtcaat tttgatgacc 597241 caggtacgta tcatctttat tttgggaatg aaggcgggaa gccgggaaca atcattacct 597301 tctttccgtg ggccggagcc cgccaaggcg tcattggaga cggtcaagtt ggcgtgactt 597361 cgtatgtcgt gccgaaaggg gctatggcat tttgggaaaa gagactagaa aagttcaacg 597421 ttccctacac caaaatcgag cgctttgggg aacaatatgt agaatttgat gatcctcatg 597481 gactgcactt agaaatcgtg gaaagagaag aaggagaggc taatacgtgg actttcggag 597541 aagtaacgcc cgatgttgcc attaaaggtt ttgggggtgc aaccctatta tcagagcagc 597601 ctgacaaaac cgctgacctt ttagaaaaca tcatggggct ggagcgagtc ggcaaagaag 597661 gagacttcgt tcgttatcgt tccgccggtg atatcggaaa tgtgattgac cttaagttaa 597721 cgcctattgg ccgcgggcaa atgggggccg gaacggtgca tcacatcgct tggcgggcta 597781 acgatgatga agatcagtta gattggcaaa gatatattgc ttcccacgga tatggtgtaa 597841 ctcctgttcg ggatagaaac tactttaatg ccatttactt cagggaacac ggggaaatcc 597901 tgtttgaaat cgcaactgat cccccaggct ttgcacatga tgaaacacag gaaacaatgg 597961 gcgaaaaact gatgctgcct gtgcaatatg aaccgcatcg cacacaaatt gaacaagggc 598021 tgctgccgtt tgaagtaaga gagttagatt gatttgacac ataaaaaata aagaaacata 598081 tattcaattg atgattgctg gatggtactg tcagcaaaga atcagataaa atcaaagatg 598141 aggagagata caaatggaag atgcaggact gttgcttatt cgtataatga ttggtgtggt 598201 gtttttgttt tatggcacac aaaaattatt cggctggttt ggcggatacg ggattaaagg 598261 aaccggacaa tggttcgaat caattggggt gaaaccagga aacgttgcgg ccgctctatc 598321 aggtcttggg gagttagtaa gcggaattct atttatttta ggcgtattcc tcccgcttgg 598381 agctgctatc ataacaatca tcatgttagg tgctatcgta aaagtccatg gagcgaaagg 598441 ttttgcgaat ggcgccggag gttttgaata taacctggtg ctcattgcag tttccatagg 598501 ggttgcactc atcggttcag gagcttacgc tttgcatttt taatacgaaa gtatgtaaga 598561 acagttgctg cttgtcagta actgttcttt tattttcaca ttttcggcaa gcttgcaggt 598621 actctgcaaa gcaaaaaagc ggatatcata aatataaatc tgtatagtga atgatacgta 598681 ttgatgagct tggtcatgaa aaacagacct atttgaagga gtaaatggat gaaagagatg 598741 acaggattac attcattagt ttctatagaa aactttatca aacagcacaa attcagtttt 598801 atttatatat caaggcctgg ctgtacagta tgtcacgcag ttctgcccca gctcagaata 598861 gtattggatc agtttccaaa catcaaattg gggcatatca atgctgacga tgtagcagag 598921 gtcgccggca gattttcagt tttcaccgtt cctgtgcttc ttttgttcat tgatgggact 598981 gagtttctaa gagaagcccg ttttgttcat tttgaacagc ttgaacaaaa gctgaaaagg 599041 gtttatcgat tatatgaagg cgaataaagg aataaggcaa aaaaagaact caaatgagtt 599101 ctttttttat tcttcactag gcgaagaagg gttatcaacc tgcccttgat cacttgtatc 599161 attatcacaa cttgctgaaa taataattga atgagaagga gagtaatctc ctaatgtgaa 599221 attcactccg taatttttgc tgttcgcagt atggctgttt tgcaagtttt gtccgatatc 599281 tgtattggcg ttttgtgtca ttccatttat cgtgagattt gagatgttga tttgagatcg 599341 catgcttcaa aaactccttt cactcagaag tagctgtcat aaaggacgct ggcagtctat 599401 ttacttctat gatattgcgt ttttatatca ttgcatcaac ataatggtaa aaataatagc 599461 gagtgaatga tcatcttttg aagatgatca acctatcagc agaaataaag ccgcctgata 599521 aagaggcggc agatcgttat atgtcatcta tgaatttgat gtatcgtttt tcgtttgcct 599581 gaaggataag atagtcgttt ttaatgatga gtaggagcct atagcagcgt agccataaaa 599641 ccagcccata aatacgccag aaaagaggct gtgtcgatgg cttatgaaaa cagaaatgac 599701 aaggcctgtt attaaggcaa ctgacggtac aaaagttttg gggattttca ataatatttt 599761 gaggatttgg gttatcaata tgatgattgg aacagctatc acagcatccc aaaagttcgt 599821 gtgaataatt ggaaaagcca tacggcacct catgaagtgt ttatttctta atttttacgc 599881 taaaagcttg gaaagcagct cttggatcgc atatgttaca ttttgggctt gattggcgga 599941 gcttgtttgg cttaaagcat tggattcaaa aaccaaacct gtattactcc caccggaacc 600001 ctctgttgtt ttagacacag agaacgggct gatggaaact gcaaatccgt tattaaaaac 600061 gctgttcccg gatatcgaat gaatataaac tgggaatttc atcattcatc tctcctctct 600121 gttatgactg tttatacaat atggtgtgtg agcagcagtt gcttaaacaa aacggcaaaa 600181 actttcagta agagacaaaa acctgcaaaa tgccacaagc gccttttgtt aatgcagctt 600241 tttagggacg ttttttttat tttttttgcc aacttcatca aaaatattct gattgccaga 600301 ctgggcttgt ccgtccttat ttatgaaatc ggggtgaatg agttttttca gatccctgac 600361 tgttaaaggc ttggcgtcat cagttaattc tattcctaat tgcccgtttg cctctaatgt 600421 cgcaattttg acatcttgta tagccgtaac gccgtgaagc cttagctgca tttcaagctg 600481 gtcagctgta agtctcatct tctttaagtt ttcgatatga agctgtccgt tttcaatgac 600541 gatttttgct tttccggtta acatcttttc aatggtgttc gatttcattt ggatccattc 600601 cataacgatg agtgtgcttg tgaaaattgc cgctgcaatt aatgttttga agaggctgta 600661 ctcgatgatt ggctgaacga taatagttcc gatcgaaatc atgacaaccg tttgagtcga 600721 cgtcatttgt gcgattgatt tccttcctga aattctcagc aaaatgaccc cggctacaat 600781 gagaacaaga gattcccaag tgaaattcat gctaccacct gaccaatgat gaattagatt 600841 tgtcatggga ttggcttttc ttccggccaa tcgcaattta atatatccga aaggcagtcg 600901 gttcattctg tcctgaaccg aacaatattt ttggtataga tggatatatt aagccaaaca 600961 atgatagcaa caggagtttt ttggccgaaa caatctggga agcggggagc gccataacat 601021 gattgaactt gaagttgtca ttagaacggt tgccagcttt ggcttgctgt taatcgcaga 601081 acgaatttta ggcaaacaga caatctctca aatgacgatt tttgatttta ttgcggcgat 601141 cacactaggg gcgattgctg ccggattagc ttacaatact tcaataaaac cgcacaatat 601201 ggccatttcg tttagtattt ttgtgctaac catttttcta atttcgtttc tgtcgataaa 601261 gaacaggaag ctgaggaaat tttttgccgg agatccaaca gtgctgattc aaaacgggaa 601321 gatacttgaa tcaaatatga ggaaaatgcg ttacacactt gattatttaa atcagcaatt 601381 acgggaaaaa gaaatattta atatcgaaga agttcttttt gccattcttg aaacgaatgg 601441 tcagctgact gtgttaagaa aaccgcaatt ccggcatgtg accaaacagg atttaatgat 601501 tgcggtaaac caagaacaaa ggcttccgat agaacttatt atggacggag aaatcattga 601561 gaataattta aagcagaatc gtttgacgga atcctggctt ttggaagaat tgcgaaaaag 601621 agacataaag gtgaaagaga ccgtgtacgc agtgctgctg ggtaatgggg atatttatgt 601681 ggatcaatat aaagaccata tatcagtccc tatggataag gaatgaagga acaatcaatc 601741 ttaaagcccc ttattgaacg caacggtttc aacttgtctt gggtacgaaa tatgcagaag 601801 cccgtttaac agctgaatct gtaacaaatg agtttcagcg gcttcgggaa gctgaatgat 601861 tcgctcaatt tctccgtaat accgttcacg cagcacttcc atttcggctg gaaaaacagg 601921 cgtgatcgtt cctttgatca gcagctgggt tttagacagt aaacggatcg ttaattcttc 601981 ctcatacaca ccgggcattt ccacaatgat aaaattatat tcctcatctt gataaaagtc 602041 gtaaacaaac gtagaagctt cggaatcaaa aaaatgttcc ggggctttat atttgagcac 602101 atttgtccaa aagtcacttt gtttatattc attcgtaatc tcaagccact ttcgaatttt 602161 ttcgaaatcc atatgagatt ctccttaaat ttgatttgaa atcggcgcag aagggtttcc 602221 gatttggtct tggtcactaa cgtctgaatc aatatttcca gtgtttaaaa gtgaagacgt 602281 aggcgaaaga tcccctaagg aaaagtttgc tccaaaatat ttgctgttcg cagtatggct 602341 gttgtgcaca gtcggaccga catctatatt tccgttttgc gtgacgccgt tgatcttaat 602401 atttgcgata ttaatttgat atggcataga cgaaacccct ttaatctaaa attggcggtg 602461 gtgcaatcgg aggagcatta acgttggatg tatcagagtt gccgatagat gtctggtcat 602521 ttacatcagg atcgtttaag aagttttcca ttacggattc tgtaggtgat gtatcaccga 602581 aagaagagtt ggtcccttga gatttttgat tgttggtagg gctgttataa gcagcttcgc 602641 ctattgtaat tgaaccattg cccgaaatac tgttgatctt caaataatat aggttgatta 602701 ctgtagacgg catcccatca cacccttcca tctttctgta cagtacatta tgcgccgctg 602761 cacccaattg ttccttgcat ttacgggcaa aactctatct ggccccggag tgatgctcaa 602821 ttatcagtga atgaaaagcc attgatatag gaatcaatga attgattcag ttattcgaaa 602881 tgcatgagac cttttaataa aggaagctgg caaacaggat cagtttgaaa taattgacaa 602941 tgaagctaat gccatgaaat aatactcgtg agtaacatta ctcgtgggta ttatttttgg 603001 ggtggtccta gttgaaaagt aaaggagtag aaagccgaaa acgattactt aaagctgccg 603061 ctaatgaatt ttcggttcgg ggattccatg acgcgaaggt aagtgaaatt gtgaaaaaag 603121 ctgggttcac gcagccttca ttttacctgt actttcaaag caaagaagcc atctttgccg 603181 agttaataac cgattttcac tctcgagtca gaaagctgac agagtcactt cttctggaaa 603241 acggattaaa cacggaggat gtgtcaaaac gggtactgct agctgtagag actgtttttc 603301 aatttttgga tgaggacaag gatttaacca agatcggctt ttttctcaac ccggaagcaa 603361 aacaaatgaa aaaagacttg gcgatggttt tgaaagagaa cttagaagca gaacagcggc 603421 ttggctattt tcactctgaa ctggatatgg aaactgtcgc tgagtgtttg gtcggcatga 603481 ttgaacattt aaccgaatca tttttgttaa ccggaatcaa agatccggca agcctcgcag 603541 cagaggttgt gaatctttta atttacggga tgcttccgaa agggaatgat gtaagatgat 603601 atctattatg atgaaagtca gtttggcagt ttttatgctt gcgggaggca tcataaaggt 603661 aagccgcgtt ccctttcaag ttgagcattg gcggcattat caatatccat tatggtttct 603721 gactgttact ggcattcttg aaatagccgg ggcacttgct atgacagcgg gaatttggaa 603781 tcggtatgca gcaattggag caggtgttct gtttgtcgtt ctcatggcgg gagcaattca 603841 tgcgcatatg tttcgagcaa gacaatctgt catcatggcg atacaagcga tgatttgttt 603901 gattgtttca atcatgatca tcatggggag ttacacgtaa gcttttcact aatgtttaag 603961 aacaagccca tttgcaggaa atctcctttt cttatcgaat aatagaaagt ccaggaatta 604021 actgaatcag taaaatagag ctccatttct gtgttattcg tccggcatca gctgggcttt 604081 ttttataaag gaggaataca ggatggcatt cactttggaa gacatgactg aggaagagtt 604141 cgaagccttt cgcgggatgt ccgtgcaaaa ttttgcgaaa caaaacataa cgtcaggaac 604201 ttggacggaa aaagaggcat ttgagaaatc ggagcaggca tatgagaaca tgattccgaa 604261 tgggcgagac agcagcaatc attatttttg gaacatcaca aatgaccaag gagaaagaat 604321 gggctggctc tggctgtatg ctgatccatt acatccgcaa aaggaagcgt ttatctattc 604381 ctttggattg tatgaagcct ttcgcggaaa aggacttgct caattggcgc ttcaaacgct 604441 tgatgaaaga gcaagagagc ttggtgcgga aaggctggct ctacatgtat ttgcacacaa 604501 cgagacagcc gtctatcttt atcagaagat gggctatgcc atgaccaata tacgtatgcg 604561 gaaacagcta tgctgaaaag ccgcttacgt tacccaaata caacatgcct atctggaagc 604621 ggtggcaggg tactataagt catcattaga aagattaagg tcatgggagg cttgaacata 604681 taaagaaaaa ggacaacagc tgttgtcctt ttcaatgccg cttgaacttt ctccctcagt 604741 cttttttgtc ttgatgatcc agctctttta ttcgtttcgt aagctcattg aaagcctgat 604801 caagctcctt atacccttta tcatttggcg tcataaaact gagctttccc agcacttctt 604861 gtctttctgt ctcaagcttt aaccgaagct cctcccgctc atttctttct gaaggaacgt 604921 cgtttaactg cttttcgatg ccgttgtttg agatgacgag tttactgttt gttgtttttt 604981 cgagaaagta tcggtcatgt gaaaccgcca gcaatgtgcc gctgtattgt gacagtgttt 605041 cttccagctg ttcgcgtgac ggcaggtcga gatggtttgt cggctcatct aaaatcagca 605101 cgtctttttc ctccagaata tatgccatca gcttgatctt tacacgctca cccatactca 605161 tatgcttgat cggttcagtc cattgggcgg ctgtaaaacc taagtgcctc atcagatttt 605221 gaacgtgccc ccttgctttg aatgtttcat tctcaaataa ctcttccggt gtttgttcta 605281 aaggcaaatc aaacacctcc tgcgttaaat agccgatgtt tgcggacggc gacacccata 605341 cacttccttc tgctgtttcc tgtcccagaa tgatgttcag taatgtcgtt tttccgctgc 605401 cattggggcc tatgatcgca accttttcgc cgtgctgaat tgtaaagttt gcgtttttaa 605461 agagagtcct ttctccaaac gcttttgtta cattctgaac ttctaaaaaa cgttttcctg 605521 ttttgtgggt tgtatcgatt gaaaagcgga ctgtatattc tggggtaacg ggttccgcct 605581 ttgctttttc aagctctttt tcaagccgct tctgcttgga ttttatctgg gcatccgtac 605641 gcttcgcttt tacccggtga tattctttaa acccttcctt tttcgtcgat tgagcatggg 605701 ctttttccga ccaagaagcg agcccattca tttgtgcttc aatccgttca accatttttt 605761 gctgcttttc atattcacgc tgctgggtga gtcttttctt ctcccggaac ttcatatacc 605821 cggagtaatt ccctttgaat tcaatcagcg tctgatcctc aagcgaccat atttttgttg 605881 cggcttcgtc taaaaaatat cgatcgtgag aaacgagaat cacagtgccg ttataatgtt 605941 tcagctgttg gatgagaaat tgcaagcttt tttcatcaag gtggtttgtc ggttcatcta 606001 acagcagcag atctgcatcc tctgatagtc ctttcgccag ccgcgctttc agtttttcac 606061 cgccgcttaa ctgatgaaaa tcacgaagag gcacatgcca tttctccagt aacttctttt 606121 cggcaggtgt ctgatccgca aaggaatacg ccgcggtttc ctgttcaacc aaagccagtt 606181 ttatatcctt ccgaaggatt tgaccctgtg caggggctaa gtcattgtga atgaggtgca 606241 gcaacgtaga tttcccagcg ccgtttttgc cgataatccc aatgatatct ccttgctgaa 606301 cactggcgtt tacatgttta aaaacagttt gatcctttac ttcatagcta acgtttgtta 606361 atgttacgat ctctttcatc catatccctc gctttaaagg gagaataaaa aaatcctccc 606421 aaatgtgttg gaaggattag ccgtgcctgt gcatgatcaa ataagctatt ttttataaat 606481 agcagtgtcg tatatataga aaatgggcag actaatccta ttttttgatt tgaaatattg 606541 atttcaaacg gtaaaaataa gattagttaa tcattgtcca cccatcatcc cttcttgttt 606601 tgattacaaa cactatagca tacctttaaa ttcaaaagca aaggtcattt tcatcaaaaa 606661 aactcctgct ctcatttttg aggcaggagt tttgagtctt attgatgctt cgcttttctc 606721 actttataaa tcacaatcag caaaataaac caaaccggtg tgacaaataa ggaaacacga 606781 gtatcctgtg ccagtgccag cacaaccaga acaaacgcca ggaacgcaag aatcaggtaa 606841 tttgtaaacg gataaagcgg aagcttaaac ttgtttgttt tcgctaattc aggtcttgtt 606901 ttgcggtatt tcatatggca gatgaccgta atcccccaaa tgtagataaa gcatacggtt 606961 gaaatacttg tgatcagggt gaatacgcct tctggcatga tgtagtttaa cgtaacaccg 607021 attaaaatca cgatagctga aaagaataaa gcatttctag gcactttacg ctgagtcagt 607081 ttcgccattg actcaggcgc attgtgatct ttcgccaggg aatagaccat acggcttgta 607141 ctgaatacag cgctgttgca tgctgaagca gcggatgtca acacaacaaa gttgataata 607201 cttgcagccc cgacgatgcc aacagcgaca aatacttgta cgaatgggct ttcgctggga 607261 ttgatgatat cccaaggata gatgctcata atcacgagaa gagccccgat ataaaaaagc 607321 agcacacgga caggaatatt gttgatcgcc ttagggatta ctttttcagg gttttctgtt 607381 tcaccggccg taagcccgac aagctcaatg ccgacaaaag caaacacaac catctggaac 607441 gagaggataa acccgtgcat gccattcggg aacaggcctc cgtggctcca gaggtttgtg 607501 aagctggaca ctcctgagct tgtggaaaag cctttgaaaa tcatcacaag gccaatgacg 607561 attaacgcca aaatggcaat gactttaatc aaagcgaacc aaaattctaa ttctccaaaa 607621 agcttgactg tcgccagatt cataatcagt aaaataataa gagcgattaa gccaggcacc 607681 cattgcggca cacccgggag ccaatattga gtgtagagcc cgactgctgt cagatcagcc 607741 atcgcaatgg aaatccagca gaaccaatat gtccagccgg tgataaaagc tgccatatcg 607801 cctaggtagt cttgtacaaa atccacaaaa gagtgatagt tcaagtttga taacagcagt 607861 tcacccagcg atctcataat taaaaagcaa atgatccctg tgatcatata agcaaataaa 607921 atcgaaggtc cggcaaaatg aatcgatttg cccgagccga gaaataagcc tgtcccaatg 607981 gctccgccga tggcgatgag ctggatatgc ctgtttttca agcctctctg caacgtttgc 608041 tgatttatat tgtctttcgt catgtcgtct gtcactttat gtgttcctcc attgaaaatt 608101 gtttattgag tcagcaatct atttttaatg attattataa cactaaaatt tctatctttt 608161 ttactaaaaa aggattgatg aaaagaattt taatgtgatt tggactattt cccgaaaaag 608221 cggctccatt tagggagccg cttttttatg ctttttcagt ttttgtcata aacaggtaga 608281 gcccgtaatc tgtcggtgcg gatgcgtagc ctgcctgccg cagcattgct gtgatattgc 608341 cgcggtggta tgtcccgtga ttgacaacgt ggggaagcag ttcggaaaca gttgttttca 608401 tgattccgct tgagggattt tgaatctgga gtggcttatt gagctgttct ttttgctgta 608461 aaaatagtat atagcgctcg gataacctca gaaaaaggtc ttccatttcc tctatttctt 608521 tagcctctgt ctgttcttta agctgttcag ctaaagccaa cgcatcgctc aaggttttgc 608581 cggaaaacac ttcaatccag ccgagatcag aaagataaac atgagacaat acatgggata 608641 ttgacggaaa cacgctttga atttcttgat ggtatatctc ttttggaagc tcttttaatc 608701 ggttgaatat ttgttgattg gcccagacgt tatattcata caatttgaat gcaaaatctg 608761 acatgttaaa attccccctt tcgtgtgtat agctttcatt atacacgaac atgagttctt 608821 atgtagagtg ctcgaaaata aaatttgttg acatatatag tttagaggaa taaactaatt 608881 gacattgaac ataaagttta gcggggtaaa ctataatgag gaggggaaga tattgaatga 608941 acaaaagcta tgtcaggcga taaacctgtt tgtggaagtc ctgcttgaag ggacagaatt 609001 tgtgcatcgt gaaatcaatc aggatgtctt caagcatatc tcaagggaac aggcagacct 609061 gttgaaaatt ttaaaagtca agggcccaac ctctcccggc agcctggcca tgtaccaaaa 609121 tgtacataag agcgcgatct ctaacagact gaaaaagctg ctcgaaaagg gattggttca 609181 atgggacgac tgtccggaaa aaagtgatag gcgctctaag cttattaaca ttacacccag 609241 tggtgaacac atactagaag aattagattc tgccatcttt aacgcgctca aaccgttgat 609301 tgatgatata gatgaggaac acttacattc tatcatcgag atattcacca ttttaaaaag 609361 caaatttaaa ggaggagatt ctgccgaatg agagcaatca tcaaattcaa gtgggcaatt 609421 gcagccatag tattagcact taccgtcgtt ttgagtttgt tttctccgaa cttaacggag 609481 ctggccaatc aaaaggggca ggcccagctt cccgctgatg ctgtttcaga aagggcaaac 609541 gccattttaa aacaagcggg agaagacaat aattcgatca gtgtagtctt tacattagac 609601 aacgctataa agaaagaaac agagaatcag ctccggataa taattgataa aatcaaaaag 609661 atcgacggtg tagaagaggt aacatctcct ctgtcagcgg aaaaagaagt caaagaccag 609721 ttgatgtcga aagacaagaa aaccgttctc atgcctgtca cgattacagg ttctgataaa 609781 aaggcggaaa aaattgcgga cgagatttat caaatcgttc ctgatgactt gacggcatat 609841 attacgggag cttcccttat caaccaggat ttcgctcaca gctcagagga agggcttaag 609901 aaaacggaag tgataacagt ctgcctgatc atcggtttac tgttgatcgt gttccgatct 609961 gttgtgacgc cttttatccc gattgtggtt gtcggttttt cttatctgat cagtcaatct 610021 atactgggca tccttgtata caatgttgat tttcctatct cgacgtttac gcaaaccttc 610081 ttagttgcga tcctgttcgg cattggaaca gattactgca tactgcttct tacacggttc 610141 cgtgaagaat tggcaaacgg gcatgataaa aaagaagcgg cgcttatcgc ttaccgcaca 610201 gggggaaaaa ccttatttat cagcggattt gcggtattga tcggattttc cgccttagga 610261 tttgcgaagt ttgcgatttt ccaatccgca gtaggggtag cagtcggtgt gggaatttta 610321 atgatcatcc tctacacact gctgccatta tttatggtga cgctgggtga aaaattattc 610381 tggccttcta agaaagtgct gtcacacagt gataacaaac tatgggcgtt tctcggcaga 610441 cactccgttg cgcgtccgtt tctgttcatt gtcatcacgg tggtgattac gcttccgttc 610501 atcttgacct atgatgacca gatttcattc gactcaactg cggaaatcag cagcgattat 610561 aaatctataa aagctctcga ggccattaag gatggattcg gggaaggaaa agcgttcccg 610621 atcaatgttg tcgtaaaagg agacaaagat cttacaacag ctgatacaat cccctatcta 610681 ggaaatatca gcaaagcgat cgagaaagtt gatcatgttg actctgttat gaccattacg 610741 cagccgactg gtaaaaaaat caaagattta tatattgata accagctagg atcggtttca 610801 gacgggctgg ataagacggt gaaagggatt gccgatgtcc aaagcggatt aacggatata 610861 gaaaacggac tgaatcaaat ggcagggcaa accggctcgg cctcaaatgg agggtctggc 610921 ggttcactgg gcgatgcggc agatggcttg ggcaaaatca atcagcagct gcagctcgtg 610981 agcaaacaga tttcccaaac cggcaatacc gcacagaccg tgcagcagct tacggcaata 611041 agcggacagc ttggccagat tcaaaccggc cttgaacaag cgaaccaaca gctctcaggc 611101 cagcaggcac aagccggaac gctgacagaa agcctgaaaa agctgtccga aggcgtgaaa 611161 agcgcaaatg agggcctgac gaaagtctct gacggtatta cagcttccag tgatatatta 611221 gaggacatga gcaaaagtcc aactgtaaga gatactggca tattcattcc tgatcaagta 611281 atgaaggaca aagactttaa gaagtcaatt gaccagtatt cctttgcaga cggcaaaggt 611341 gttcaattaa gtgtcgttct ggattcaaat ccgtactcag aacaagctat tacgacaata 611401 aaccaaatca aaaaagctgt cgcaaacgaa gttgacggca ctcctttgga gaatgcacag 611461 atcgtgtacg gcggggtcac gagtatgaat gcggacttaa aggagctatc cacaacggac 611521 ttctccagaa caatggtgat tatgattata ggcctgttta tcgtgttaac cattttgttc 611581 cgctcaatga tcatgccgat ttatatgatc gcgtcattgc tgctgacgta ctatacgtcg 611641 atatccataa cagaattaat ttttgtaaac ggcttaggaa acgcgggtgt cagctgggca 611701 gtgccattct tcagctttgt catcttgatc gcgttagggg tagattattc gatcttcttg 611761 ctggatcgat ttaaggaaga ggtgcacctt ggcattgagc aaggtgtcgt caggtcaatg 611821 agcaaaatgg gatctgtcat tattacagct gccattatat tggccggtac gttcgcggcg 611881 atgatgcctt caggtgtcaa tacactgatg caggtggcaa gtgttatcat catcgggctc 611941 ttgctttacg gccttgtcat acttccgctc ttcatcccgg caatcattgc gacctttgga 612001 gaaggaaact ggtggccgtt cggcaggaag aaaggaaaag agtaatcgag agaagagtga 612061 tgaatggtca tcactctttt ttcatgacta aacgactaac ttcagacgtg ttacccaaaa 612121 agatcagacg atcaaacggc ggctgtactt aaaaacaaag agcccggaaa acattcccgg 612181 gctctttgtt ttatttccat tctgcaattg tatcaatcgg cagacggtag gaagcatagc 612241 cttcgtctgc tgcttttccg atagaaagta gcataaccgg tacataacgt tctttatcta 612301 atccgaaggt ttccgcgatg ttttctttat cgtatccgcc gatcgggttt gtatcgtagc 612361 catgcgcgcg tgcagtcagc atcagctgca tggaaacaag acctccgtca atcaggatcg 612421 tttcacggtt gacctgtgcc ggaagctttt caaaatgtgc ggtcagcgcg gcgatttgtc 612481 tgtctttgac ctcctgcggc atgtaaccaa gttccacggc ttttgaatag atttcttcta 612541 gatagtctgc gttgttcatg tctgcaaata cagcgatgac agcagatgat gttgtgactt 612601 gtgtttggtt aaagcttgca agcggtgcga gcttttcttt tccttccggg ctgtcaatga 612661 caagaaaacg ccatggctgc gcgttaacag aagatggggc agttgttgct tcctctaaga 612721 tctctgtcat ttcttctttg ctgattttta ctgccggatc atagttgcgg atagaacggc 612781 ggcctttcat aatttccata aaatcgtttg ttttgatcat gttgatacac tcctcttaag 612841 cttcgatatt atttatattg tttcgcatgc gcgccagcac atcaatgagc aggcggcgtt 612901 cttctgcgct tacatttgcg agcatttcct tcatgaaacg ctccttttcc ttcttagaag 612961 actcaattcg ctctcttcct tggtctgtta accgaacaag ggtgatgcgg ttgtcctcag 613021 gcttgcgccg ccttgatacc atgcctttgg attccagctg tttcaggtgt ctggtaacgg 613081 ctgcgctatc gatatttact ttcttttgaa ggtcgctttg actgatctca tctgcatgat 613141 aaagcaatgt cagcaattcc aaacgagatt ggctgatgcc cgtgcatgcc tcgaacttca 613201 cgccaatcac cttgttcacg ccttgcagct gatataaaat ctcggcttcc tctgaacaaa 613261 atgacgccaa aacccatccc ttctttcctg tcaaaactat taattgatat atcaatgatt 613321 gacacgtcaa ttaatataca acgattgatt tcatcttgca agccatttgc acttttgaac 613381 aacctcccag cgcataaaat tcgctaggct agaacttagc aaaaaaagct ggccgcttct 613441 tcagatgatg ctggtcacga tgattccctg catcattccc atttataggt gttcggaata 613501 tcactttgcc ggcccgtgct caagcggctt tcacaggctg aaagttatga tacaatatac 613561 aaatgtttca cagcttcaat ccatagttgg agctgacatc cattatataa gggactaggt 613621 tgaagggaag gtttgataac atgctgcaca atccaactgg aaaagaacgc ttggcactag 613681 cgtttctgct cggcatgctt gctatattgg gcccgcttaa tatagatatg tatttgccaa 613741 gttttcctga aatcgcgaaa gatttatcag caagtgcttc acttgttcag ttaagtttaa 613801 cagcctgtct ggtcgggctt acgatcggcc agctgattgt cgggccggtc agcgatgcgc 613861 agggaagacg aaaaccgcta ttaatctgta tttttttatt tgcgttatct tctctgtttt 613921 gtgcactgtc gcccaatata acaactttag tggctgcgcg ttttttacaa ggcttcactg 613981 cttctgcagg gcttgtgctg tctcgcgcaa tcgtccgcga tgtgtttacc ggaagagagc 614041 tttctaaatt tttctcgctg ttaatggtca ttaccgcggt ggcgccaatg gttgcgccta 614101 tgacaggcgg tgccattttg cttttgccgt tcgcaacgtg gcatacaatt tttcacgtct 614161 taatgatcat cggattttta ctagttcttc tgattgcatt gaggttaaaa gaaacgcttc 614221 cgctggaaaa acggattcca agctcaatcg gaacatccgt caaaacgatg ggcagcctgc 614281 tgaaggatcg atcctttatg gggtacgcgt taactgtcgg atttattcac gggggaagct 614341 ttgcatatgt gtctggtacg ccttttgtat accaggatat ctacggggtg tctccgcagg 614401 tatttagtat tctttttggc attaacgggc tggcgattat atcgggcagc tttatcatcg 614461 gacgctttgg cggaatcatt catgaaaaaa gcctgcttcg tatagcggtc attacggcta 614521 tgattgcgac ggctgtgcta ttaaccatga ccatgattca cggtcctctt gctacattag 614581 tcatatccat tttcatttac atgattacga tcggcatggt tctgaccagc acgtttaccc 614641 tagccatgga aaagcagggg caccgcgccg gaagtgcaag tgcgctgctt ggaatgcttc 614701 cgctgctcct cggttcaatc gtgtcaccgc ttgtaggcat taatgagaca acagccgttc 614761 cgatgggagc catcatgttt gtgacagctg tcatcggctc actggcgttt tttggattaa 614821 cgaaagaacg agtagggcag aattcataaa aaaacctgac atgacgtcag gttttttgtt 614881 ttatttagaa taacaacagc aggcctgcaa tcgccggagt caaaaagatg gctgatttca 614941 aaaccacctt tggcatgagg ttggtgaatt tcgcgcctac ataggccccg cacattgtcc 615001 cgaccagaac tttgacaagt aaaacgtaat caacaaaacc ttctgtaata tatccgatgc 615061 ctccacctac agccagaggg atgatcacaa gcatcgtcgt tccgacagaa tggcgaatgg 615121 acagattcag cataatcatt aaaccgattt gaataaaagg tgccgacccg atgccgaatg 615181 tgccggaaag aacgccggct gcaattccta agatgaccgc tctcgtatac gttgaaagag 615241 tgctttgatt cacttgagcc ttctctttta aaataaataa tctgattaaa atgagaattg 615301 ctgataaaaa taacattcca gccgtcaaat aatgaagcaa atcagccgga ataaaagaag 615361 tcagcttggc gccgaaaaat gagccaaccg cagcaaagcc tccgactatt aagccgattt 615421 tcatttgaat gttaccctcg cgatagtggc tgtatgcccc tgataagctt gtaaaagcca 615481 tgccggcaag cgaagtgcct aaagccgtat gaatcgggat atggaaaaga agcgttaaaa 615541 gggcaatgac aaagccggct ccaccggcgc caataaagcc taaaataatt cctagaagaa 615601 acataacaag aataatgagc atattttttc ctccattgaa aagatgtaaa aatgtaatcg 615661 tgcgctattc tggcggaggt atggtgtcct attgacgaag aaaaacacgc cgttttttca 615721 gttgccagta gtccgtcgac cgtcgttcag caaacatatc gtacctcaaa ttcagggatc 615781 tgacaaggca gtttgttgct tcccattacc atctgttata tgattttgat gaagaaaagc 615841 ccttgaatat attcaaaaga ggtattatat atggacgatt ttaaattaga taagccgact 615901 ccctactacc tgcaatttta taaccagcta aaaaaaatga tcttcaacgg gacttttaag 615961 cctggggaac ggataaacga aacacagctg gcgaaaagct ttggcgtcag ccgctctccg 616021 ataagggaag ccatgcgatt gcttgagaaa gatggtttgt taaaagcgga tgaccgaaat 616081 gggttttcga tcacgtcgtt aacggcaaaa gatgtagatg agatttataa aatcagaatt 616141 ccgctggagc agctggcagt cgaattagtc atagacgaag cggacgaaga agagctgacc 616201 atactcgaaa aacagcttga agaaacagag aaagcgattc acaacggcac ggaagataca 616261 gaaatcattc gtttaaacca aaaatttcat gagctgctgg ttgatttcag ccataacaga 616321 catttgaaaa atttgcttga gcatgtaaat gacctgattc atttttgcag aatccttaat 616381 tataccggcg accaccgcgc agaaacgata ctgcgtgagc accgcaggat atttgaagaa 616441 gtgaaaaaga aaaacaaaga agcagccaaa caacatgtgc tggctcattt caatcatgac 616501 tgtgagcatt tgaagcatgt gcttgaagaa ggtaaagaga attgatttgt atgatccggt 616561 accaagggag agcagaaccc ttggtatttt tttatgtatt caccacatat ctaagaggcc 616621 ccgttaataa gattttatga tggtttgact aacgaataat gggggttaaa tatgtttatc 616681 catatcgtcg ggcctggtga ttctttgttt tcgataggca gaagatacgg tgcttctgtt 616741 gatcaaatac ggggtgtgaa tggtttagat gaaacgaata tcgtgccggg gcaggctctg 616801 cttatccctc tttatgtata tacagtccag ccgagagata cgcttaccgc cattgcagct 616861 aaagcgtttg tgccattaga gcgactgcga gcggccaatc cgggcatcag cccaaatgct 616921 ttacaagcgg gagcaaaaat aacgattcct tcgatctcaa attacattgc gggaacgtta 616981 agtttttatg tgctccgaaa cccagacctc gatcgggaat taatcaatga ttatgcgcca 617041 tactcgtctt cgatttcaat tttcgaatac catattgcac cgaacggcga cattgcaaac 617101 caattgaatg atgcggccgc tattgagaca acttggcaaa gacgagtcac gccgctggca 617161 acaataacga accttacatc aggaggcttc agtacggaga ttgttcacca agtgctaaac 617221 aatccgacag cgagaaccaa tctggtcaac aacatttatg acttagtttc cacaagggga 617281 tatggcggtg tcacaatcga ttttgagcag gtgagcgccg cggatcgcga tcttttcact 617341 ggatttttac gccagctgag agatcgactt caggcgggag ggtatgtgct gacgatagct 617401 gttcctgcaa aaacaagtga taatatccca tggctgaggg gctacgatta cggggggata 617461 ggagcggttg tcaattatat gtttatcatg gcttatgatt ggcatcatgc gggaagtgag 617521 ccgggtcctg tagcgccgat tactgaaata aggagaacca ttgagtttac gattgcgcag 617581 gtgccgagca gaaaaatcat tatcggagtc ccgctctacg ggtacgactg gatcatcccg 617641 taccagccgg gcacagttgc ttcagcgatt tcaaatcaaa acgcaatcga aagagcgatg 617701 aggtaccaag ccccgataca atattcagcc gaatatcaat caccgttttt ccggtacagt 617761 gatcagcagg ggcggacgca tgaggtatgg tttgaggatg tcagaagcat gagccggaag 617821 atgcagatcg tccgtgaata cagattgcag gctattggcg cttggcagtt aacgctgggc 617881 tttacgccgg gcccatggct tctgcggaaa ttttttacga tcagaaaagt gtaaaaaaag 617941 acaccagagc ttgggtgtct tttttttgat taagtccaga gcagcagaat agttcattca 618001 tttgtacctt gcatgggttg tgttcccatt ttacgattag tagtagtctg atcaaacaaa 618061 gagtcagaat acgatttgag agggagttgt ctacatgaag acagtattga ttttgaattt 618121 tcctgcggaa ggccatgtga atcctacttt aggcattacg aaagcgtttt ccgataaggg 618181 atatgatgtc cattatatat ccactgaaaa atataaaaaa cgattagaag cagcgggagc 618241 aacggtccat cttcaccggg atctgctgcg aacgacacct attcatgtcg gttcgcccaa 618301 tggcattctt gatttcgtga aaatccatat caaaacgtca ttggacattt tacagattgt 618361 caaagactta tctaagagca ttcaatttga ttttgtttat tatgataaat tcggcgcggg 618421 ggaattggtg agggattact tagatattcc aggggtctct tcatcggcgt ctttcctgtt 618481 tggcgaggag catctgaaaa tcctgccgct gcatccggag tctggagcgc cgcttgaatt 618541 ggatcaagag tgcgaagacc ttttggcaaa aatgaaagaa acgtacggtg ttgccccgaa 618601 aaacctggtt caattcatga acaataaagg ggaattgaac gtagtgtata caagccgtta 618661 ttttcagcca gaaagtgatc gtttcgggga tgaatgtcta tttatcgggc cgagctttcc 618721 aaagagagcg gaaaaaacag atttcccgat tgaacagcta aaagatgaga aggtcattta 618781 tatttcaatg gggactgtac tggatcatac agaggatttc ttcaaccttt gtattgatgc 618841 attttcaggc tttaacggaa aagtcgtcat cgctgccgga gaaaaagcgg acctgaccaa 618901 attaaagcag gcgccggaaa actttatcat tgctccgtat gtccctcagc tggaagtgct 618961 ggagcaatcg gatgttttca ttacacacgg cggaatgaac agcgtaaacg aaggcattca 619021 tttcagcgtg ccactggttg tcatgcctca tgacaaggat cagccgatgg tggcgcagcg 619081 tctctctgaa ctccatgcag gctatgtcat ctctaaagat gaagtcaatg cccaaatatt 619141 aaaacaggcc gtagatgagg ttttgcgcaa cgatcagtat acggcaggca ttaaaaaaat 619201 caatcaaagc ttcaaagaat gtatggacat ggaagaagtg atggagcgga ttgatgagtt 619261 gattcgccaa aaaaacaaat aagaaaaaga actcccgtac cttgtacggg agttcttgat 619321 ttaaaacttg attttgattt tttgagcatc actgattttc ttatggttat ggtcaaagac 619381 gtcacttgtc gtgatttcga tccacttgat ctcttttgtt ttcttctcag catccgcggc 619441 cttatcatga gcatggccgc ttgatgcgtt cacaataaag ccgagatttc cggacttttc 619501 ggcgccgcct tccaattcgc cgtttaactc ttcaagataa atatctttgt tccaatcaaa 619561 ggtttcaccc gtatttgttt tcatcaatgc aatcggcgca acatttactt tttttgtaga 619621 ggtgttcttg atatcaacga aaaccttaac gaaatcaaac tcttcatcgt gtgttaactc 619681 atgaaagtaa tcaatcatgc tgtagtccgg gcgcaagtgg atcagcttca tttcttttac 619741 tgttaactcc acgtcgccaa ttttataggt tttgttcact tgtttgatat cttttaagac 619801 agcttttcct ttatcatctg aaaacgtttg gccgacctta tgcaatgtcc ggtcatcagt 619861 tacctgggaa ttaggctgat aatcatctgt gctgtccttc tgggatgaag tgctttgcgg 619921 ctcagctttt actgttttct ccccgcctgc atgctgtttt tcagtactgg cgtttgatga 619981 gcagcccgca agcatgatag caaaaacgag aattgaaaga attcttctca tgatgattcc 620041 tccattaaaa agagatcccg ttacttcata caagcaacgg gacaccttgt attcttttac 620101 ttatcgttaa tcttaatgtt gtattgtaaa gccttgaaaa catttttggc gatttctgta 620161 ttgtcgattt ggccggcaaa tgtctcacta gacggaccgt atgcatagac gggaacatct 620221 tcaccggtat gtccgcctgt tgtccatcca gtgtgagagc gtttattaaa gatgttctcg 620281 attgcgttat cgatatccag tacttccttc gattttgccg cttcttcaac agattgaatt 620341 tcggcttttg ttaaagccaa tttcttttga tcgatatatg ttttcaacgt tttttcaaca 620401 tccgcgccgt cagcgatctt ttctgccata aagtctggtg tgcgctttgc ggctttaatg 620461 ggttcactga accagttgta gatgccgtcc gcaccgatgg aatatccgcc ggttgagtgg 620521 tcagccgttg cgacaaccaa tgtgtgcttg tcttttttag cgaaatcaat agccgcctta 620581 taagcttgtt cgaagtcttc catctcgctc atggcgccaa cgatatcatt gtcatggccc 620641 gcccagtcaa tctggctgcc ttccaccatg aggaagaatc cgtctttatc cttgtttaat 620701 tttttaatgg ctgtgtttgt catatcttta agtgatggaa tatccttcgt acggtcaatc 620761 tttttaggca ggccgccgtc agcgaatagg ccgagaactt ggctgtcttt gtttttcagc 620821 atgtccttgc gatcatccac gtagctgtac cccgcctttt tgaattcctt aatcaaatta 620881 cggtccttac ggtcaaaatt gctctttcct ccgcctagaa ggacatcaat tttgtgcttg 620941 ccgttgacca tctcatcaaa ataatcatcc gcaattgagt tcatattttt tcggctgtgg 621001 tcgtgtgaac caaaagaggc cggagtggcg tgtgtaattt ctgaagtggc cacaagtcct 621061 gttgcttttc ctttttcttt cgcagcttca agcaccgttt tggcttctga cccgtcgtta 621121 tcaacggcta tggcattatt gtatgtttta attcccgcag acatagccgt tgccgccgct 621181 gcagaatccg ttacattttg ttcaggatca tcggggtaag ttgtttgctg gccgacaaga 621241 tactgatcaa aagccgtagg ctccacaact tttgtctttt tattatcctt taagtatcga 621301 taagcagacg tataagacac acccatacca tcaccaatca gaacaataac atttttaatt 621361 tcgtcttggt tccccttttt cttttcctgg gcgctggctt caggcacact gccgctggct 621421 aagctgctga acgcaattga tgataaaacc gcgataggca gtaatttctt cgggaatttt 621481 ttcaactgga taacctccta aatatagatg aatctcaatg acaacccaat tatattttta 621541 aactgttaag ctagtattaa tcgattttaa agattggatt tacaagaata atgaactggc 621601 acccttaaat aatggttatt cttttatgag aagttttaga aggaaagagc gatagtacta 621661 aagaaataaa ttggaggaat agatactggc cgtggatagg cggactgaaa tctgctatag 621721 tcgcatagaa gcaacccgct tacatcttga acaatttaaa gtattacgtt ggaaagaggt 621781 attgtgtaag cacatgtctg agcagttcat atggagtggc atcattttat tttaggaggg 621841 aacaacatgg acgttttttc tgagtactta gcggggattg ctgacccgtt ccaccgagaa 621901 agaacggaag aggtgttaac ttggataaaa aataaatatc caaatttaca tacagaaata 621961 aaatggaatc agccgatgtt tacggatcac ggtacattta ttattggctt tagtgtttct 622021 aaaaagcatt tagctgtcgc tcctgaaaaa gtaacgatag cgcacgtaga ggatgatatt 622081 gtgaaggccg gatatgatta caccgagcag ctgatacgta tcccttggaa cggtccagtt 622141 gattatacgc tacttgagaa aatgattgag tttaatattc tggacaaggc ggactgctcc 622201 actttttggc ggaaatgaag aaaaaggcat aacatatgag ctgtataaaa tatgttacgc 622261 cttttcattt gtctattttt cgttttgatc atctattgct gcttttcatc aaacaaggtc 622321 ttttcattga gcgtaagctg actcgcagaa taatgattac cttgtttcca tttcacttca 622381 atcgtaatat catggccttc aagctcatgt tcatctaacc gctctaaaaa agaaacggac 622441 ttttcttttg cgcttccatc agaaaaagtg cctccagcat aatcatgcat cgggatttcc 622501 gtgtcagaac tcagcagaac ttcatcatcc ttttttacaa tcagtgattc cagataagtg 622561 ttgtctattt caattgtatc accgatccaa taaagtttgc cgctgtattc attcggtgca 622621 tcttcatttt ttgtgaaaac agcttcccaa ttctgatctt tgctttctcc ctgccaattt 622681 ggatactcca aacgaacatg atgaatcagg tgataggaaa aaaagatcaa gcagaaagcg 622741 attaatagga atgccgtgaa aatgagaggg tatttataat gactggacat aaaagactcc 622801 tattcgttta atcaattacc ttcgaaaata gaatttcatc ccgaatcaaa atgccgtttt 622861 cagccacctc gggaatctcc ggcttgagtc ggcgcgcttt ttcaactgcg ttcggaaaca 622921 ctgcggcgaa ttgatagcct ctcttttgat aaaacgctat cgcatttaca ttatcattcg 622981 ttgtgataag ctttattcgt tgacaatgtg catgtttagc cttctcttca acctgctgaa 623041 gtaaagctgt gccgattcct ttattttcaa tcatactatc taatgaaata atttcacaat 623101 ctttcccatc tattgtgtat gtaatacagc caatgatttc gccgctttca tttactgcgg 623161 caaatccatc taattcatca caccgaaaaa tgccgctgga aatcgccatc tcgggtgtac 623221 cccaatgctt ggcaaaaaaa tcggtcaaca tatgtttcgc tatctcattg tttgggatga 623281 tgatcatcat aacactcctc tattgaaaga ttgcatatgt actatcaata taaacaatat 623341 ataacaaaaa aaatagatgt tgaggtgacg gcatggaaat cagcgatatc atttacgggc 623401 agcaccatat agacggagtg ctggaagagc ttatcaaaag cgctcctgtg caaagattaa 623461 aaggaatcta tcaaggcgga gcaagctttt tagtcaatcg aaagtggaat gtgaccaggt 623521 atgagcactc catcggcgtg atgctcctca tcaaaaagct cggaggaacg atagaagaac 623581 agattgcggg tctgctccac gacgtatcac acacagcttt ttctcatgtg gtcgacgttg 623641 tctttgaaaa tcaagcagaa gactatcatg aaaacatctt tcaacaagtc attgttcact 623701 ctgaaatccc ggacatttta caaaaacacg gctatcatac tgaagaactt ttatctgacg 623761 attcaaggtg gacattgctc gaacagcccg caccggagct gtgtgctgat cggacagact 623821 atacgctgcg tgatatgtac cgatatggac acattaacct gcacgaagcg caaacctttt 623881 tggatcatct tattgtgaga aacggaagga tgtttcctga tagtattgaa gccgccgaat 623941 ggtttgtcag tgtgtactac aaggaagtaa ttgatttctt tttgaatcct gtgaatgtat 624001 atggatatga atatttagcg cgagcattga aggcagcgct gcggcatgat gtcatatctg 624061 cagaggatct gctgaaaacg gaccaagagg tactgaacat cctgcgtgca tcaaaaaatg 624121 aagaagtcct gagcttgctt acatccattc atcccggcat acaagtaata gaggatgaca 624181 tccagtacga tttccatcaa aagaagaaaa tgcgcctaat cgatccatcc atttttcttg 624241 atgacaaatg gatcaaatcc tcaggtgttt ctgaaaaggt gaggaaaatg ggtgaggccg 624301 cttatcaaaa agcaaaaaaa ggtgtgtata taaaaatctt aaagcagtaa ttgccgcctg 624361 acagcggctt tttttatgtt tggctttgca aacaaagggg aataggacaa actgcgggaa 624421 cgctttatga gaatatcagc gtatttacat accgttcggg ggtatagtat tatcgagagg 624481 gcatgttttc attgtctgcg ggcaaaagtt acaggaaaaa aatgaagcaa aggagaatga 624541 acatgaaaat ctctaaatat gcactgggaa ttctgatgtt atctctagtt tttgttttat 624601 cagcatgcgg caataacaac agtacgaaag aaagcacaca tgacaatcat tcagactcct 624661 caacacatga agagatggac cattccggat cagctgacgt tccagaggga ttacaggaat 624721 ctaaaaatcc gaaatacaaa gtaggcagcc aagtaatcat caatacttct catatgaaag 624781 gcatgaaagg tgctgaagct acggtaacag gcgcctatga tacaacggcg tatgttgttt 624841 cttatactcc gactaatggg ggacagcgtg tggatcatca caaatgggtg atccaagaag 624901 aaatcaaaga tgccggagat aaaacgttac aacccggaga tcaggtgatt ttagaggctt 624961 ctcatatgaa aggcatgaaa ggagcaacag ccgagatcga ttccgcggaa aaaacaactg 625021 tatacatggt tgactacaca tcgacaacga gcggcgaaaa agtgaaaaac cacaaatggg 625081 tcacagaaga tgagctttca gctaaataat aaaaaatcct ccttttacaa ggaggatttt 625141 tttgctgttt gaacaggtct tgttaaagaa atgaaagcaa acaggacagc gatgatcaca 625201 atcgatccgc cgcaccatgc cgttgacacc acagtacccg tctgatccaa aacaacaccg 625261 ccaatggctg agccaagggc aattccgact tggagggccg atgtgttaaa gctttgctga 625321 atgtcagacg aatcaggtgc aatttcaatt aaatagcttt gctgagccgg ggcgaggctc 625381 cagctcagaa gaccccaaat caccatgaca ggcaaaaaga aaatcataga cgatgtagac 625441 agcggcagta agaacataat gatggcaaag gaaccggtca ccagcaaaat gctcttaaag 625501 gaaccaagcc ggtcagatag cgctcctccg aaagggcctc cgcatacagc agatatcccg 625561 aaaaggaaat aacaaatgct gacccagaaa gagctcaggt gaagagtctc ttctaaaaac 625621 ggcgcaaagt aagcgtaaag cgtgtagtgg ccagctaatg taaacatcgt gacgaggtgt 625681 gaactcgcga ttttcagatt accgatcgtc ttgagttgtt cccggaaagg aatcattttc 625741 tccgccggta ttctttcaaa gaagattgaa ataatcagca tggagatcag tgccaacagg 625801 ccgatgccaa ggaacaaaat ccgccacccg aaggaatcgc tgattaagat tccgagcggc 625861 acgcctaatg cgatagcaga gctgaatccc ataaaaataa ttccgattgc gcgggctctg 625921 tattcaggcg ctacaatttt cggggcaatt gttaaagaaa gcacaacaat cagccctgta 625981 ctcattgctg ccaataccct agataccatc agtgttgcga aattagggct gaaataggcg 626041 acaagattgc taaggaagaa aacaaataaa gcaattagat ataagcgctt ccgctcaatc 626101 ttcgcagtca atgccaaaag cagcggccca gatactgcat atcccagcgc aaacacactg 626161 atcagctgtc cggctgaaac aatggaaatg tctaaatcat ttgcgatctg aggaagaatt 626221 ccccccacaa ttaactcaac caatccgact gcaatcgtag aagctgcaag caggaaaact 626281 ttgaaattca taacaaactc ctttacttaa atgttttgat aaataaaaaa aatcctgatt 626341 acaaaaaatg tcataaacaa attttgtaat caggatttta cggttcctgg tagacaccct 626401 caaaccatat tattgaggtt atacaagtga taatagctat ttaattgatt cgtttccgtt 626461 gatgagtgta ccacattatg aatgaatctt ccatagaaaa atttataaaa cggtgaaccg 626521 gaaaaaaata tgattatatt tattttataa aagtatagac atttaaaatt aaatgactat 626581 aataatcaat gtaagcgttt taataacagg ggggatagca gttgaaaaaa atattactcg 626641 cgtgcagttc aggaatgtct accagtttat tggtgacaaa aatgaaggaa tacgcacagt 626701 ctatcggtga ggaagcggag atttgggctg ttggccagga taaagcaaaa gaagacatga 626761 gaaaagcgga tgccgttttg atcggtccgc aaatgagctt tctgaaaagc gagctccaaa 626821 aagaagcaga tcaatacaac attcaagttg aagtcattga catgatggcc tacggaatgg 626881 cagatgggaa aaaagcgtat gagcaggcat tgtccttaat ggtgaatcaa taatggaaca 626941 gatgaaaatc acgaatttaa cagacgagca aatcagtttt cagctaatcc tgcacagcgg 627001 aaatgcccgc agctgcatca tacaatcact gcgcgcctat aaagaaggga aaaaggacga 627061 ggctgatgcc ctcattgcca aggcggagca ggatttatcc gcggcccatg acattcactt 627121 tcaaatgata cagaaggaat ccggcggaga agcaacagct ttttcattgc tgcttatgca 627181 tgcagaggat catctgatgt caacattatc catgaaagaa ttagtgaaag agatgcttga 627241 tctctttaaa accaagaata tataaaaaat cggggtggat agggtgttcg agaaaatcag 627301 ccaattcctt gttccaattg cagggaggtt aaacaataac cgctatttgc aagtgttgcg 627361 tgatgcattt atgctggctt tcccgctgac gatattcggg tccatttttg tcgtgttaac 627421 gaatttgccg tttctaaaca aaatcatgaa cgcctcaatg cttacgtcgt ttcagtctca 627481 tttcggcatt gcctccacgg cgacaatggg cattatgtct gtctttgttg tgttcgggat 627541 aggctattac ctgtcgaaaa gctatcaggt cgaagctgta tttggcggag cgatcgcttt 627601 ggtttccttt ttgctcttaa cgccatttat cattcagccg gaaacaggtg atgccattac 627661 aggggttatc ccggtcgatc gtctcggtgc aaaagggatg tttcttggga tgattacggc 627721 atttctttct ggcgaaattt acagaagaat cgttcaaaaa aacctgacaa tcaaaatgcc 627781 agccggcgtt ccgcctgctg tagcaaaatc attcgccgca cttattccgg cttttatcac 627841 attgactgta tttttgctga ttaacgtaat ggtgactctg ttttttaaaa caaatatgca 627901 cgacgtcatt tatcatgcga ttcaggctcc gcttgtcgga cttggaagcg gtatcattcc 627961 aacactgatt gccgtgtttt tcattcaaat tctttggttt ttcggactgc atggacagat 628021 cattatcaac tccgtgatgg acccgatttg gaatacactg caggtagaaa acctttctgc 628081 ttacacggcg ggaaaagaaa tccctcatat tatttcaaaa ccgtttatgg agatttatac 628141 agtagggatg ggcggaacag ggatgacgct tgcgattgtg tttaccattc tcatattcat 628201 gaaaagcagg cagatgaagc aagtatcaaa acttggcctc gctcccggta tttttaacgt 628261 aaacgaaccg attatctttg ggcttccgat tgtcatgaat ccgatcatta ttgtgccttg 628321 ggtgctggca ccgatggttg ttacgctcgt cacctatctg gctatgtcag ccgggctcgt 628381 tccgcctcca actggtgtga cagtgccgtg gacggttcca ttattcatta atggcatcat 628441 ggcgacgaac tcaatcatgg ggggcgtgat gcagcttatc aatctgctga ttgtcttcgt 628501 gatctggttt ccgttcctaa aagcaatgga taaattaaat ctggcaaaag aaaaagaaca 628561 ggctgtgcag gagacagctg ctcagcaaaa tgataacagc ataaaaatgt gacataaggg 628621 gagagagact tggcacatac agaacaatat cgttttccaa aggatttttg gtggggatca 628681 tccgcttcag caacacaaat ggagggtgcc gccgacagag acggaaaagg ccagaatata 628741 tgggattatt ggtttgaaaa agaaccgcat cgtttttttg atcatgtcgg acccgcagac 628801 acatcccaat tttacgacaa ctataaagaa gatatcaggc tgatgaagga acttggccac 628861 aactcgttcc ggatgtcgat ttcctggtca cgtttaatac caaacggaac gggcgagatc 628921 aacgataaag ccgcagattt ctataacaat gtcattgatg agctgatcgc taacggaatt 628981 gaaccttttg tcaatttgtt tcatttcgat atgccgatgg cgcttcaaaa aatcggcggc 629041 tgggtcaaca gagagacggt tgacgcgtat gaaaactatg caagaacttg cttccgtttg 629101 tttggcggcc gggtgaaaaa atggttcacg cataatgaac caatcgttcc cgtagaaggc 629161 ggatacctat atgattttca ttatccaaac aaggtcgatt ttaaagaggc cgtccaggtt 629221 ggatttcata cgatgctatc aagtgcccgc gccattcagg cttacaggga gatgaagcag 629281 gacggaaaaa tcggcatcat cttaaatttg accccttcat acccgagaag cagccatccg 629341 gcggatgtga aagccgggga aatcgcagac gcgtttttta acagatcttt tttagaccca 629401 tctgtcaaag gcgaatttcc caaagagctg gttgacattt tgaagcatga aggctttatg 629461 cctgattaca acgctgaaga tctcgacatc atcaaaaaga acacggttga cctgttggga 629521 gtgaattatt accagccgag acgtgtgaaa gcgaaagaac atcttccgaa tcccgacgct 629581 ccttttttgc cggacaggta ttttgatccc tacgtcatgc cgggccgcaa aatgaatccg 629641 catcgcggct gggagatcta tgaaaaaggc gtttatgata ttttgatcaa tttaaaagaa 629701 aactacggca acatcgagtg ttttatctct gaaaacggta tgggggttga aggtgaagag 629761 cgattcaggg atgaacaagg catcattcag gatgattacc ggattgaatt tataaaagag 629821 cacctcaaat ggattcaccg cgccatacag gaaggctcga acgtaaaagg ctatcactta 629881 tggacgttca tggacaactg gtcttggaca aatgcctata aaaaccgata cggatttgta 629941 tcagtcaatc ttgagaaaga cggagaaaga accgtcaaaa agagcggaaa atggttcaaa 630001 gaggttgctg agcatagcgg tttctagatt ttcctaaagg tcaagatctt ccggcaatca 630061 tcataacgaa tagagatgac gaaaatccgc aacattgatg aaatagggaa aagaacttat 630121 gatatccgta aaagcttatg tgatatcaaa cagctgccgg aggataccaa tgaataaata 630181 cgaaatcatt gcaaatgaaa tgagaaatag aattaaaaat aacgtatatc cgatcgatca 630241 gcccattcct gatgaagtat ctcttgcaaa agaatttaac tcaagccgca tgacgatgaa 630301 gagagccttg gataatttag ttgccgaggg tctgctgttt agaaaacgag gccatggcac 630361 gtttattatt caatctgcaa tacaggatga ccatgtccat gtagtcagca atgagattct 630421 cggattgacc aacttgctga aagataaaaa aatcaaaagc aaggtcattc agtttgaagt 630481 gcaatttccc actgaggaag tggccgccca tttgtctatt gatcagaaaa caccggttta 630541 ttatgtcgtt cggctgcgaa ttgtagaagg tgaaccctat gtattagaaa aaacatatat 630601 gccgactcat ttaataccgg gcattaatga cgatgtcctt catgattcga tctacaatca 630661 tattacaaat gtgctgcagc tcaaaatcgc cggaacgcat cggaaaatca gagcctgcaa 630721 atctgatcat attgaccagc agcatctggg ctgtaaacag gatgatccaa ttcttgaagt 630781 ggaacatgtg ggcttcttag ataccgggat tccatttgaa tattcctttt cacgtcatcg 630841 gcatgacaag tttgttgtga cttctgtaaa catacggcgc tgattgcgga gacaacaagg 630901 aggccatctg catgcttggc ggtattgaag caggcggcac aaagtttgtt tgtgctgtcg 630961 gtagagaaga tggaacgatc attgacagga tagaattccc cacaaagatg ccggatgaaa 631021 cgatagagaa agtaattcaa tattttagcc aattttcatt acaggcaatc ggcatcggct 631081 cctttggtcc cgttgataac gataaaacca gtcaaacata cggtaccatt acggccacgc 631141 cgaaagcggg ctggagacac tatccctttt tgcaaaccgt taagaacgaa atgaagatcc 631201 cagtcggatt tagtacagat gtcaacgctg cggcgctggg tgaattcctt ttcggtgaag 631261 cgaagggtct tgacagctgc ctgtatataa cgattggcac tggcatcgga gcgggggcta 631321 ttgtagaggg gaggctcctt caggggctgt cacacccaga gatgggccat atttatatcc 631381 ggaggcaccc ggatgacgta taccaaggga agtgccctta tcatggagat tgctttgaag 631441 gcttagcttc aggccccgct atcgaagccc gctgggggaa aaaagccgcg gatttatcag 631501 atatagcaca agtctgggaa ctggaagggt actatattgc ccaagcactg gctcagtata 631561 ttttgatcct tgcacctaaa aaaatcattc ttggcggcgg cgtcatgcaa cagaaacaag 631621 tgttttctta tatctatcaa tatgtaccaa aaatcatgaa cagctactta gatttttctg 631681 aattatcaga tgatataagt gattatattg tacctccacg tttaggcagt aacgccggaa 631741 tcatcggcac gctagtttta gcgcatcagg ccttacaagc agaggcagca tccggggagg 631801 tgcgatcatg acgcatccat tatttttaga gcctgtcttt aaagaaagac tatggggagg 631861 gacgaagctt cgtgacgctt ttggctacgc aataccctca caaaaaacag gtgagtgctg 631921 ggccgtttct gcacatgccc atggctcgtc gtctgtaaaa aatggcccgc tggcaggaaa 631981 gacacttgat caagtatgga aagatcatcc agagatattc gggtttccgg atggtaaggt 632041 gtttccgctg ctggtaaagc tgctggacgc caatatggat ctctccgtgc aagtccatcc 632101 tgatgatgat tatgcaaaac tgcacgaaaa tggcgacctt ggtaaaacgg agtgctggta 632161 tatcattgat tgcaaagatg acgccgaact aattttggga catcatgcaa gcacaaagga 632221 agagttcaaa caacgaatag aaagcggtga ttggaacggg ctgctgaggc gaatcaaaat 632281 caagccagga gatttctttt atgtgccaag cggtacactc catgctttat gtaagggaac 632341 ccttgtcctt gaaatccagc aaaactctga tacaacatat cgcgtatacg attatgaccg 632401 ctgtaatgac cagggccaaa aaagaactct tcatatagaa aaagccatgg aagtcataac 632461 gataccgcat atcgataaag tgcatacacc ggaagtaaaa gaagttggta acgctgagat 632521 cattgtttat gtgcaatcag attatttctc agtgtacaaa tggaagatta gcggccgagc 632581 tgcttttcct tcatatcaaa cctatttgct ggggagtgtt ctgagcggat caggacgaat 632641 cataaataat ggtattcagt atgaatgcaa tgcaggctca cactttattc tgcctgcgca 632701 ttttggagaa tttacaatag aaggaacatg tgaattcatg atatctcatc cttaatgaat 632761 gggggagttg catttgttta agaaacatac gatctctttg ctcattatat ttttacttgc 632821 gtctgctgtt ttagcaaaac caattgaagc gcatactgtg tcgcctgtga atcctaatgc 632881 ccagcagaca acaaaaacag tgatgaactg gcttgcgcac ctgccgaacc gaacggaaaa 632941 cagagtcctt tccggagcgt tcggaggtta cagccatgac acattttcta tggctgaggc 633001 tgatagaatc cgaagcgcca ccgggcaatc gcctgctatt tatggctgcg attatgccag 633061 aggatggctt gaaacagcaa atattgaaga ttcaatagat gtaagctgca acggcgattt 633121 aatgtcgtat tggaaaaatg gcggaattcc gcaaatcagt ttgcacctgg cgaaccctgc 633181 ttttcagtca gggcatttta aaacaccgat tacaaatgat cagtataaaa aaatactaga 633241 ttcttcaaca gtagaaggaa agcggctaaa tgccatgctc agcaaaattg ctgacggact 633301 tcaagagttg gagaaccaag gtgtgcctgt tctgttcagg ccgctgcatg aaatgaacgg 633361 cgaatggttt tggtggggac tcacatcata taaccaaaag gataatgaaa gaatctctct 633421 atataaacag ctctacaaga aaatctatca ttatatgacc gacacaagag gacttgatca 633481 tttgatttgg gtttactctc ccgacgccaa ccgagatttt aaaactgatt tttacccggg 633541 cgcgtcttac gtggatattg tcggattaga tgcgtatttt caagatgcct actcgatcaa 633601 tggatacgat cagctaacag cgcttaataa accatttgct tttacagaag tcggcccgca 633661 aacagcaaac ggcagcttcg attacagcct gttcatcaat gcaataaaac aaaaatatcc 633721 taaaaccatt tactttctgg catggaatga tgaatggagc gcagcagtaa acaagggtgc 633781 ttcagcttta tatcatgaca gctggacact caacaaggga gaaatatgga atggtgattc 633841 tttaacgcca atcgttgagt gaatccgtaa tgtcacaatt aagaaggtgc tcaagaagtt 633901 tcttgagcac cttcccactg gattaagcat tcatatcgcc taacccagga ctgtgttcat 633961 ttggtatttc aggaagcact ggtacgggaa accctgccgg aggatctatt acttgtaact 634021 ctccgccatt tcggcttgga gatttccctt gatagatttc actgattctc gtttcatcca 634081 acctaaagtt aaaatgtgta ttatggtagc ctaattcgac atactttctg cactcaggat 634141 atttattaat gtcataattc ggcacaggga gcagcttcgc ccattcaacg cccaatgtct 634201 cgagcgcttt cgcgaatgca ttctggtgag cattgtcgcg tacaatcaga aaagcaagtg 634261 tttcgcggaa cgtctgatta gagctcattt cataaattct tgttttttgc agcacacctg 634321 tcgactcaag aagcaggtta tccagcaggt cagtaattaa gtttccgtgg ttatacaccc 634381 acgacccgtt ccacggattg ccccctgcat caacaggaag ggaactttgc gctccaataa 634441 tataatgatg aggattagca tgtttaaccg cttcatcaag tggcgcttga tctgtacctt 634501 gactgccgac accttcaccg cctgattcat ctaataaagc attgattgtg ttttgaacca 634561 gttcaacgtg ggcaatctcc tctaaaaaaa tgccgcgaag cagatcgcgg tactgtttct 634621 gctttcctct gaaattagag ctttggaaaa aaactgcatc attgtacgca tttctccgta 634681 atgaccgcct aatatctcct gcaggacctt agcagctgcc gggtctggct tgtccggttt 634741 aatgatatta atcagttcct ctttgtagta atacataaca cgcctcattt cttcttaaga 634801 gattttctta tattatttgt aagatgagat aaaatatata catgataagc atgggaaggc 634861 gtgaaagaag aaaataaaaa aatacaggaa aagtgttgac caaataaaac aggcatggta 634921 tattattaaa cgtcgctgat gaacagcgtg aaacaaaaca gaaaaacaaa aaagttttcc 634981 taaggtgttt acaagatttt aaaaatgtgt ataataagaa aagtcgaatt gaaaaagatt 635041 cgaaaaaaca ttaaaaaact tcttgacttc aacatcaaat gatagtatga tagttaagtc 635101 gctcaataag cgcccgtagc tcaattggat agagcgtttg actacggatc aaaaggttag 635161 gggttcgact cctctcgggc gcgccatata agataccacg cgggtgtagt ttagtggtaa 635221 aacctcagcc ttccaagctg atgtcgtgag ttcgattctc atcacccgct ccattattga 635281 atgatctttg aaaactaaac aagacaaaac gtacctgtta attcagtttt tgaaaatcgc 635341 acagcgatgt gcgtagtcag tcaaactagg gcctgcacga tgcaggtcac acaggtgtca 635401 ccgcgggatg cggtggactt aacctgtgat ccatttatcg gagagtttga tcctggctca 635461 ggacgaacgc tggcggcgtg cctaatacat gcaagtcgag cgaacagatg ggagcttgct 635521 ccctgatgtt agcggcggac gggtgagtaa cacgtgggta acctgcctgt aagactggga 635581 taactccggg aaaccggggc taataccgga tggttgtttg aaccgcatgg ttcaaacata 635641 aaaggtggct tcggctacca cttacagatg gacccgcggc gcattagcta gttggtgagg 635701 taatggctca ccaaggcaac gatgcgtagc cgacctgaga gggtgatcgg ccacactggg 635761 actgagacac ggcccagact cctacgggag gcagcagtag ggaatcttcc gcaatggacg 635821 aaagtctgac ggagcaacgc cgcgtgagtg atgaaggttt tcggatcgta aagctctgtt 635881 gttagggaag aacaagtacc gttcgaatag ggcggtacct tgacggtacc taaccagaaa 635941 gccacggcta actacgtgcc agcagccgcg gtaatacgta ggtggcaagc gttgtccgga 636001 attattgggc gtaaagggct cgcaggcggt ttcttaagtc tgatgtgaaa gcccccggct 636061 caaccgggga gggtcattgg aaactgggaa acttgagtgc agaagaggag agtggaattc 636121 cacgtgtagc ggtgaaatgc gtagagatgt ggaggaacac cagtggcgaa ggcgactctc 636181 tggtctgtaa ctgacgctga ggagcgaaag cgtggggagc gaacaggatt agataccctg 636241 gtagtccacg ccgtaaacga tgagtgctaa gtgttagggg gtttccgccc cttagtgctg 636301 cagctaacgc attaagcact ccgcctgggg agtacggtcg caagactgaa actcaaagga 636361 attgacgggg gcccgcacaa gcggtggagc atgtggttta attcgaagca acgcgaagaa 636421 ccttaccagg tcttgacatc ctctgacaat cctagagata ggacgtcccc ttcgggggca 636481 gagtgacagg tggtgcatgg ttgtcgtcag ctcgtgtcgt gagatgttgg gttaagtccc 636541 gcaacgagcg caacccttga tcttagttgc cagcattcag ttgggcactc taaggtgact 636601 gccggtgaca aaccggagga aggtggggat gacgtcaaat catcatgccc cttatgacct 636661 gggctacaca cgtgctacaa tggacagaac aaagggcagc gaaaccgcga ggttaagcca 636721 atcccacaaa tctgttctca gttcggatcg cagtctgcaa ctcgactgcg tgaagctgga 636781 atcgctagta atcgcggatc agcatgccgc ggtgaatacg ttcccgggcc ttgtacacac 636841 cgcccgtcac accacgagag tttgtaacac ccgaagtcgg tgaggtaacc ttttaggagc 636901 cagccgccga aggtgggaca gatgattggg gtgaagtcgt aacaaggtag ccgtatcgga 636961 aggtgcggct ggatcacctc ctttctaagg atattatacg gaatataaga ccttgggtct 637021 tataaacaga acgttccctg tcttgtttag ttttgaagga tcattccttc gaaacgtgtt 637081 ctttgaaaac tagataacag tagacatcac attcaattag taatacaaga tatcacatag 637141 tgattctttt taacggttaa gttagaaagg gcgcacggtg gatgccttgg cactaggagc 637201 cgatgaagga cgggacgaac accgatatgc ttcggggagc tgtaagcaag ctttgatccg 637261 gagatttccg aatggggaaa cccaccactc gtaatggagt ggtatccata tctgaattca 637321 taggatatga gaaggcagac ccggggaact gaaacatcta agtacccgga ggaagagaaa 637381 gcaaatgcga ttccctgagt agcggcgagc gaaacgggat tagcccaaac caagaggctt 637441 gcctcttggg gttgtaggac actctgtacg gagttacaaa ggaacgaggt agatgaagag 637501 gtctggaaag gcccgccata ggaggtaaca gccctgtagt caaaacttcg ttctctcctg 637561 agtggatcct gagtacggcg gaacacgtga aattccgtcg gaatccggga ggaccatctc 637621 ccaaggctaa atactcccta gtgaccgata gtgaaccagt accgtgaggg aaaggtgaaa 637681 agcaccccgg aaggggagtg aaagagatcc tgaaaccgtg tgcctacaag tagtcagagc 637741 ccgttaacgg gtgatggcgt gccttttgta gaatgaaccg gcgagttacg atcccgtgca 637801 aggttaagca gaagatgcgg agccgcagcg aaagcgagtc tgaatagggc gcatgagtac 637861 gtggtcgtag acccgaaacc aggtgatcta cccatgtcca gggtgaagtt caggtaacac 637921 tgaatggagg cccgaaccca cgcacgttga aaagtgcggg gatgaggtgt gggtaggggt 637981 gaaatgccaa tcgaacctgg agatagctgg ttctctccga aatagcttta gggctagcct 638041 caaggtaaga gtcttggagg tagagcactg attggactag gggcccctac cgggttaccg 638101 aattcagtca aactccgaat gccaatgact tatccttggg agtcagactg cgagtgataa 638161 gatccgtagt cgaaagggaa acagcccaga ccgccagcta aggtcccaaa gtatacgtta 638221 agtggaaaag gatgtggagt tgcttagaca accaggatgt tggcttagaa gcagccacca 638281 tttaaagagt gcgtaatagc tcactggtcg agtgactctg cgccgaaaat gtaccggggc 638341 taaacgtatc accgaagctg cggactgttc ttcgaacagt ggtaggagag cgttctaagg 638401 gctgtgaagc cagaccggaa ggactggtgg agcgcttaga agtgagaatg ccggtatgag 638461 tagcgaaaga ggggtgagaa tcccctccac cgaatgccta aggtttcctg aggaaggctc 638521 gtccgctcag ggttagtcgg gacctaagcc gaggccgaaa ggcgtaggcg atggacaaca 638581 ggttgatatt cctgtaccac ctcctcacca tttgagcaat ggggggacgc aggaggatag 638641 ggtaagcgcg gtattggata tccgcgtcca agcagttagg ctgggaaata ggcaaatccg 638701 tttcccataa ggctgagctg tgatggcgag cgaaatatag tagcgaagtt cctgattcca 638761 cactgccaag aaaagcctct agcgaggtga gaggtgcccg taccgcaaac cgacacaggt 638821 aggcgaggag agaatcctaa ggtgatcgag agaactctcg ttaaggaact cggcaaaatg 638881 accccgtaac ttcgggagaa ggggtgctct gttagggtgc aagcccgaga gagccgcagt 638941 gaataggccc aggcgactgt ttagcaaaaa cacaggtctc tgcgaagccg taaggcgaag 639001 tataggggct gacgcctgcc cggtgctgga aggttaagag gagcgcttag cgtaagcgaa 639061 ggtgcgaatt gaagccccag taaacggcgg ccgtaactat aacggtccta aggtagcgaa 639121 attccttgtc gggtaagttc cgacccgcac gaaaggcgca acgatctggg cactgtctca 639181 acgagagact cggtgaaatt atagtacctg tgaagatgca ggttacccgc gacaggacgg 639241 aaagaccccg tggagcttta ctgcagcctg atattgaatg ttggtacagc ttgtacagga 639301 taggtaggag ccttggaaac cggagcgcca gcttcggtgg aggcatcggt gggatactac 639361 cctggctgta ttgaccttct aacccgccgc ccttatcggg cggggagaca gtgtcaggtg 639421 ggcagtttga ctggggcggt cgcctcctaa aaggtaacgg aggcgcccaa aggttccctc 639481 agaatggttg gaaatcattc gcagagtgta aaggcacaag ggagcttgac tgcgagacct 639541 acaagtcgag cagggacgaa agtcgggctt agtgatccgg tggttccgca tggaagggcc 639601 atcgctcaac ggataaaagc taccccgggg ataacaggct tatctccccc aagagtccac 639661 atcgacgggg aggtttggca cctcgatgtc ggctcatcgc atcctggggc tgtagtcggt 639721 cccaagggtt gggctgttcg cccattaaag cggtacgcga gctgggttca gaacgtcgtg 639781 agacagttcg gtccctatcc gtcgcgggcg caggaaattt gagaggagct gtccttagta 639841 cgagaggacc gggatggacg caccgctggt gtaccagttg ttctgccaag ggcatcgctg 639901 ggtagctatg tgcggacggg ataagtgctg aaagcatcta agcatgaagc ccccctcaag 639961 atgagatttc ccattccgca aggaagtaag atccctgaaa gatgatcagg ttgataggtc 640021 tgaggtggaa gtgtggcgac acatggagct gacagatact aatcgatcga ggacttaacc 640081 atatttttga atgatgtcac acctgttatc tagttttgag agaacactct caatttgttt 640141 ggtggcgata gcgaagaggt cacacccgtt cccataccga acacggaagt taagctcttc 640201 agcgccgatg gtagtcgggg gtttccccct gtgagagtag gacgccgcca agcattactt 640261 ttatcatcgc ggggtggagc agttcggtag ctcgtcgggc tcataacccg aaggtcgcag 640321 gttcaaatcc tgcccccgca accaaatata tggttaaata aggagtgccc taagggtgca 640381 accaaaataa tcctatacaa atatggtccg gtagttcagt tggttagaat gcctgcctgt 640441 cacgcaggag gtcgcgggtt cgagtcccgt ccggaccgcc attaatgtaa acgaaacgat 640501 catgttttcg ttttttttgt gttttctttt actgtatctt ctgcttggtg tcatagccaa 640561 gctttcttta tatcgggaac atcttggata ttccagcaaa attcgataaa ctaggaagag 640621 cacaaatagg cataagcagg gttgaaagga ggttttggtt catggatgaa tttgatttga 640681 tacatagcat tactccgcgg accattcacc attcttccgt tgatgtagga ataggtgatg 640741 atgcagcgct ctacactgcg aaacacggcg ttcaggaaat tgtttgtgtt gatactatgg 640801 tagaagacgt gcacttcaaa ttacactatt cctcacctga agatatcggg tacaaggcgt 640861 tagccgttaa tataagtgat attgccgcga tgggaggcat tcctaagttt tatctggtat 640921 cacttgcggt accttcaaaa tggactgaat ctgaaatcaa ggcgatgtat gaaggaatga 640981 atgaactggc gaaactatat catatggatc tgattggcgg cgatacagtt tctaccgctg 641041 acaaattagt cgttacagtc actgtaatcg gtgaaattga aaagggacag gcctgtttgc 641101 gcagcttggc aaaaccgaat gatattgtgt ttgtaaccgg tgaaatcggt tcttctgcag 641161 cagggctttc tttattgctg gaagagacta atcctcaaaa ctcatctgtg gaaacggatt 641221 actttatcca caggcataaa cggcctgagc caagagtaag cgtcggcaga ttatgctcga 641281 tttttaaacg ggcagcttta aatgatgtta gtgacggatt ggctagtgaa ctgaacgaga 641341 ttgcagaagc cagctgtgtt tcaattgaaa ttgttgaaag catgcttcca attcattctg 641401 atttgcctaa gcttcatcct aactggaaag aatgggcttt gtttggcggt gaggattttg 641461 agctgacagg gacggtttca aatgaggagt gggaagtgtt gaagcaggag tgcgcagcgc 641521 ttcatcttcc cattacaaag attggctatg tcagggaaaa aacaaaatct aaagtgatcc 641581 taaaaacaga tcaaacatca atgatcttag agaaaaaggg atataatcat tttaaataag 641641 acgggtgact cgtgtgaagc aattaaaatg gagaactgta aatccagaag aaacaaaagc 641701 aattgccaag ctgacggcag cgtttgctaa accgggagac gtcctgacat tagagggcga 641761 tttaggtgca ggaaaaacga cttttacgaa aggttttgca gaagggctgg gaattacacg 641821 tattgtaaac agtccgactt ttacaattat aaaagaatat aacgatggcg tacttcctct 641881 ttatcacatg gatgtgtata gaatggaaga tgaaagtgaa gatttgggac ttgatgaata 641941 ttttcacgga caaggtgtct gtctcgttga atgggctcat ttaattgaag aacagctgcc 642001 acaggagcga ctgcaaattg tcatcaaaag agctggtgat gatgagcggg aaattacctt 642061 tactgctgtc gggaatcggt atgaaatgct ttgtgaggag ttaagtagac atgacaatat 642121 tagcaattga tacatcaaat tatacattgg gcattgcgct gcttcgagaa gacactgtta 642181 tagcagaata cattacatat ttgaaaaaga accactctgt aagagcgatg cctgctgttc 642241 attcattgct gaatgattgt gatatggcac cgcaggacct ttctaaaatt gtcgttgcaa 642301 aaggccctgg ttcatacaca ggagtaagaa taggtgtgac gttggccaaa acacttgcct 642361 ggtctttaga cattccaata agtgctgtat caagtcttga gacgcttgcg gcaaatggcc 642421 ggcattttga cggtctgatc agcccaatct ttgatgctag acggggacag gtgtacacag 642481 gtctgtatca atataaaaat gggcttttag agcaagttgt tccagatcaa aatgtgatgc 642541 tggcagattg gctggagatg ctaaaagaaa aggaccgccc tgttttgttt ttaggccatg 642601 atacttctct tcacaagcag atgatcgagg atgtgcttgg aacaaaagga ttcattggaa 642661 ctgccgccca gcataacccg cgcccttcag aattggcttt tctcgggaag gaaaaggaag 642721 cagctgatgt tcatgggctt gtcccggatt acttgcggct ggcagaagct gaagcgaaat 642781 ggattgaaag tcaaaagtag ggtgatagga tgaaaacaaa agcagcggtc agaaatatgc 642841 ggcttgaaga tatagatcac gtatacgaaa tcgaagcatc ctcctttacg tctccttgga 642901 cgaaggattc gttttatcat gagctgctgg aaaatccgta tgctcattat ctcgtgattg 642961 aaaaggacgg ccatcttgct gggtattgcg ggatttggat tgtgatggac gatgcccaga 643021 ttacaaatat agcgataaaa ccagagtatc gcggccagtc tttaggagaa acgctttttc 643081 gctcagctgt tgaactgtgc aaagaaaaag acgcaaggcg gctttcgctt gaagtgaggg 643141 tttcgaatca tcctgctcaa ggcttatata agaaattcgg gatgcagccc ggcggaataa 643201 gaaagaacta ttatactgat aacggggaag atgcgttaat tatgtgggtg acgataaatg 643261 agtgagcaaa aagacatgta cgtattagga attgaaacaa gctgtgatga gactgctgca 643321 gctattgtga aaaacgggaa agagatcatt tcaaacgtag tagcctctca aattgaaagc 643381 cataagcgct tcggaggcgt tgttccggaa attgcttcaa gacatcatgt tgaacaaatc 643441 actttggtta tagaagaggc gtttcgcaaa gctggcatga cgtatagtga tattgatgcg 643501 attgcagtaa cagaaggtcc gggactggtg ggagcgcttc ttatcggagt gaatgccgct 643561 aaagcattga gctttgcata taacattccg ttagtaggcg ttcatcatat agccggtcat 643621 atatacgcga accgtcttgt agaagacatc gtgttcccgg cactggcatt ggtcgtttca 643681 ggaggccata cagaactggt ttatatgaag gaacatggat catttgaagt cattggggaa 643741 acccttgatg atgcggcagg agaagcctac gacaaagtgg cgcggacgat gggattgcca 643801 tatccgggtg gaccgcaaat tgacaagcta gctgaaaaag ggaatgacaa tattccgctt 643861 cctcgcgcat ggcttgaaga aggctcttac aacttcagct ttagcggatt gaagtctgcg 643921 gtgatcaata cgcttcataa tgcatcccaa aaagggcaag agattgctcc ggaagatttg 643981 tctgccagtt tccaaaatag tgtgatcgat gtcttggtaa ccaaaacggc gcgcgcggca 644041 aaggaatatg atgtcaaaca ggtcctttta gccggaggag tagctgcaaa cagaggcctc 644101 agagctgcat tagaaaagga atttgcccag catgaaggga ttacgcttgt cattcctcca 644161 ttagctttat gcacggataa tgctgcgatg attgctgctg ctggtacaat tgcttttgaa 644221 aaaggaattc gcggtgcata tgatatgaat ggccagcccg gccttgaatt gacttcttat 644281 caaagtctca cgagataata gcgtgagact ttttatctgt ttgttattaa cagacaattc 644341 acaatttatc cacatatctg tgagtaatta tagagatatt gatggataaa gggctgaggt 644401 cactgttaat aaagtggata aattcagaat attttgtgga tagtgtgtat aaagcgctta 644461 ctttgtttat ttattagggg atgttctgtg gataaaaagc acctctaaaa agaggtgctt 644521 gactttttta atcttcttct gtggatagtt cttcccattc ggacaaaaga gattccagct 644581 cctgattaag cttctcattg tctgcatgga tagcttgtac tttttcatga tcctgataga 644641 cttcagggtc acatagcaat tcatcattgc ggctgatgtt ctcctcaatg gtttgaacgg 644701 tggtttcaat ttcttcaatc cgacggagtc gttggcgctc tttctttttc cattcttttt 644761 cttcctcgta ggaacgtttg gagtcagact tcactgtagc tggcgtttta tcagtttcct 644821 cttgctgatt cattttctcc aattcaagct gctctgtttt tttctctgta taataatcgt 644881 aatctcccag atactcctct atatggcttg aagaaagctc caatactctt gtggcgattc 644941 tgttaataaa atatctgtca tgtgagacaa ataacagtgt gcctggataa tcaatcagcg 645001 cgttttcgag aacttctttg ctgtctaaat ccagatggtt cgtcggttca tcaaggatga 645061 gaaagttggc tttttgaagc atcagcttag ctagagccaa tcttgctttt tcgcctccgc 645121 tcagtgaatg aactggtttc agcacatcat ctccggagaa taagaaattt ccgagacacg 645181 ttctgatttc tttttctggg agcccggggt actcgtccca cagctcatca aggacacgtt 645241 tagaggaagt caactcagcc tgttcctggt cataatagcc gacactgaca tttgagccgt 645301 aagaaattgt tccctgatct ggttttaggg tgtctattaa tgttttcagc aatgtcgatt 645361 tacctattcc gttagggccg acaagcgcag cgctttctcc tcttgtgagc atgaatgaca 645421 cttctgttaa aagcggcggc tggttttcat agctgattgt gagatcctga acacgaagga 645481 cttcatttcc gctctgtttt gtaatatcaa aatgaaagtt tgcggatttt tcatcgccaa 645541 gcggttttga catgacatcc attcgctcaa gctgctttct gcggctttgc gcccttttgg 645601 tggtagaggc tctcgccaga tttcgatcta cgaagtcctg cagctttgca atctcgtcct 645661 gctgcttttc atacattttc agatcttttt catactgcgc ggctttttgg tcgagataag 645721 cgctgtagtt gccgtgatac tttttgcttt ctgctcttga tacctcgtat acctggttta 645781 ctactttgtc caaaaagtag cggtcatgcg aaacgatgag aatggcgcct gaatagcctt 645841 gtaaataatg ctcaagccag gtaagcgtat caatatccag atggtttgtc ggctcatcaa 645901 gaatgagcaa atcaggctgt gttaatagaa gcttacctaa agccagtctt gttttctggc 645961 ctccgctgag gctttgaacc tgtgtagaat cgtcaaaatg gctgaagccg agaccatgca 646021 gcacagatct aacatccgct tcatattgat aaccgccttt atctttgaat tcctgctgaa 646081 gacggtcgta ggttttcatg atgctttcta attcacccgg gtcagctgcc gccatttttt 646141 cttccatagc ccgcatttcc ttttccattg cttttaagtg gtcaaaaaca gtcagcagct 646201 cttcttttat ggtaagctta gaatccaagc cagtatgctg ggcgagatat cccattgtaa 646261 tatctttcgg tttaataatt tcgccctttt catacgaaag ctggcctgcg ataattttaa 646321 ggagcgtgga ttttccggcg ccatttcttc ctacaatggc gatgcgatca cgatttctga 646381 cttccagctt tatattgttt aaaatagtat cagcaccaaa tgatttggac agctgattaa 646441 cttgtaagat catcatatta tttcacctct gctataataa gttaagtgta gcttatgaac 646501 cagaagtcag caaacaatac attggccata taagacatag agaagaaaat agtgtatgat 646561 ctgtttaagg agcgttttaa tatgaatgga ttttctcatt ttaatgaaca gggcagagcc 646621 cagatggtgg atattagcga aaaatcttcg actgtccgta ctgcggcggc tgtttcaagc 646681 gtacacatga agaatgaagt gtacgagaaa atacaaagtc acgatatcgg caaaggagat 646741 gtactggctg tcgcacaggt ggcaggcatt atggccgcaa agcaaacgtc gaatatcatt 646801 ccgatgtgcc atccgctttc attgagcggg gtagatatat cgtttgactg gaaaataaaa 646861 gaagcagaag ttatacttca tataaaagca caggtcaaaa cgaaagggag tacaggtgtg 646921 gaaatggaag cgctcacttc tgcatcggtg tgcgctctta ccgtttacga tatgtgcaag 646981 gcccttgata agggaatggt catcggccct actttcttgc tggagaagac aggcgggaaa 647041 aacggtgact ttaaaagaga actatccgag tataatttgg aggaccaaaa atgaataagg 647101 atcaatcaaa aattccgcag gcgacggcga aacggctgcc gctttactat cgctttttaa 647161 agaatctgca tgcgtcagga aaacagcgtg tatcatccgc tgaactcagt gatgccgtaa 647221 aggttgattc tgccacgatt cggagggatt tttcctattt tggagctctt ggcaaaaaag 647281 gatacggata taatgtggat tatttgctgt cttttttccg gaaaacgctt gatcaggatg 647341 agatgacaga cgtcatcttg attggtgtcg ggaacttggg aacggcattt cttcactata 647401 atttcacaaa aaacaataac acaaaaattt ctatggcttt tgatataaat gagagtaaaa 647461 taggaactga ggtaggcggc gtgcccgtct ataaccttga tgaccttgaa caacacgtaa 647521 aagatgaatc agttgccatt cttacagtgc cagcagttgc cgctcaatcc attacagaca 647581 gattggtcgc attaggaatc aagggaatcc ttaattttac gccggcccgt ttgaatgtgc 647641 cggaacacat tcgaattcat catatagatt tagcagttga gcttcagtca ctggtttatt 647701 ttttgaagca ttattcagtt ttagaggaaa tcgaatagag ggaaaggagg agcccaaata 647761 tgccgatcgg tcctggaagc cttgctgtta tcgcaatcgt tgctctgatt atcttcggtc 647821 ccaaaaagct gcctgaattg gggaaagcag cgggagacac acttcgtgaa tttaaaaacg 647881 ctactaaagg attaacgagt gatgaagagg aaaaaaagaa agaagatcag taagttagga 647941 tgacacgaat gaaagtgaat caaatgtcgc tgctggagca tattgctgag cttcgaaaac 648001 ggttgctgat tgtagcgctg gcgtttgtcg ttttctttat tgctggattt tttttagcaa 648061 agccgattat tgtgtatctg caagaaacag atgaagcgaa gcagcttacg cttaacgcgt 648121 ttaacctgac agacccgctt tatgtgttta tgcaatttgc gtttatcatc ggcatagtct 648181 tgacctcgcc ggttattctt tatcagcttt gggcttttgt gagcccgggc ctctatgaga 648241 aagagcgcaa agtaacgctc agctacattc cggtctctat tttgctgttt ttagcgggct 648301 tatctttttc atattatatt ttatttcctt ttgttgttga ttttatgaag cggatttctc 648361 aggacttgaa tgtcaatcag gtgatcggaa ttaatgaata ttttcatttt cttctgcagc 648421 tgacgattcc gtttggactg ctgttccaaa tgccggtcat cctcatgttt ttgacaaggc 648481 tcggaattgt gacaccgatg ttcttggcga aaatcagaaa gtatgcgtat tttacgctgc 648541 tggtgatcgc agccctgatt acaccgcctg agcttctgtc ccatatgatg gtcacagtcc 648601 cgcttttgat tttatatgaa atcagtatcc ttatatcgaa ggccgcttat cggaaagcac 648661 agaaaagcag tgctgccgat cgggacgtgt cttctgggca ataataaaaa atccatttct 648721 catgcgagaa atggattttc tttatttttg gttctttttg attttaaatg aaaaggcgaa 648781 catcttaaaa gaaatgctga tgttgtaagc ggcgaacacc atcagcagga tggagtaaaa 648841 tgaccacatg ctgcctggcg agcttgcggc aagataagta aagatgcacc ctacggcaaa 648901 gtagatcatt ccccaaacta ccgggtttct cataaaaata atcctccaat aatcaattgc 648961 atttgtgtgc tctgctgttc aaggtaatta cgaacaggct caagctgcat gatgacgacg 649021 aatgtattca tcattaaatg ggcgaaaatc ggcacccata tccgttttgt tctcgcatat 649081 aaaaaggcaa aggtaaagcc cattgctgta tatagaagga gatgcttcaa atcagcgtga 649141 acaataccga agataaccga gctgatcagt cctgcgaaaa agaaattcgt tttttcgtac 649201 agcgcgccga aaatgatttt tctgaagatg atttcttcta atataggccc gacgatggaa 649261 gaaacgataa tcatgagcgg gactgcctga atgacatcca gaatcgcttg tgtattttct 649321 gattctcttc cgatgccaaa aacataatat tcaatagagc ctgctattcc ttgagagaaa 649381 agggcaatga aaaaaccggc tatcgcccaa aggatagaaa gtccgattga gtccttctgt 649441 ccgtttcgca gcgtttcttt cggaacggtt ctcagaatga gcagaacaac aacgagacag 649501 gcgataaagc tgataacgga ccataatcct tgtgcatgca gcatattttc atctgtaggc 649561 tgtcctccgg cataaccgaa tttaaataac aagggaatcg cgattaatgc ggaaaactgc 649621 atgatgatat atgtcaaaat aataaaccaa tactgttttc tcaaatggta tgtactcctt 649681 tgttaagtgg gtttcgttca tctacagcta ttgtaacata atcggtacgg gggtgaaaaa 649741 gctaacggaa aagggagcgg aaaagaatga tgtaagcgtg aaaaattttt tatcttatca 649801 cttgaaattg gaagggagat tctttattat aagaattgtg ttagcactct ttagtgctga 649861 gtgctaaaat tacatattca tactattgag gaggttattt cattgttaaa gccattaggt 649921 gatcgcgttg tcattgaact cgtagaatct gaagaaaaaa ctgccagcgg aattgtgttg 649981 ccggattctg caaaagaaaa accgcaagaa ggcaaaatcg tggcagctgg ttcaggtcgc 650041 gtgttagaaa gcggagagcg cgttgcttta gaagtaaaag agggcgaccg cattatcttc 650101 tcaaaatacg caggtactga agtgaaatac gaaggtactg aatacttaat cttacgtgaa 650161 agcgacattt tagctgttat cggctaattc ttaaataaac aatacttaaa acatttgagg 650221 aggtcttgta aacatggcaa aagaaattaa gtttagtgaa gaagctcgcc gcgcaatgct 650281 tcgcggtgtc gatgcacttg ctgatgctgt taaagtaact ttaggaccaa aaggacgcaa 650341 cgtggttcta gagaaaaaat tcggttctcc gttaatcaca aatgacggtg taacaatcgc 650401 taaagaaatc gagctagaag acgcgtttga aaacatgggt gctaagcttg ttgctgaagt 650461 agccagcaaa acaaacgacg ttgccggtga cggtacaaca actgcaacag ttcttgcgca 650521 agcaatgatc cgtgaaggcc ttaaaaacgt aacagcaggc gctaaccctg taggcgtgcg 650581 taaagggatg gaacaagctg tagcggttgc gatcgaaaac ttaaaagaaa tttctaagcc 650641 aatcgaaggc aaagagtcta tcgctcaggt tgctgcgatc tctgctgctg atgaggaagt 650701 cggaagcctt atcgctgaag caatggagcg cgtaggaaac gacggcgtta tcacaatcga 650761 agagtctaaa ggcttcacaa ctgagcttga agttgttgaa ggtatgcaat tcgaccgcgg 650821 atatgcgtct ccttacatgg taactgactc tgataagatg gaagcggttc ttgacaatcc 650881 ttacatctta atcacagaca aaaaaatcac aaacattcaa gaaatccttc ctgtgcttga 650941 gcaggttgtt cagcaaggca aaccattgct tctgatcgct gaggatgttg aaggcgaagc 651001 acttgctaca cttgttgtga acaaacttcg cggcacattc aacgcagtgg ctgttaaagc 651061 tcctggtttc ggtgatcgcc gtaaagcaat gcttgaagac atcgctgtcc ttactggcgg 651121 agaagtcatc acagaagatc ttggccttga cctgaaatct actcaaatcg ctcaattggg 651181 acgcgcttct aaagttgtcg ttactaaaga aaacacaaca atcgttgaag gcgctggcga 651241 aacagacaaa atttctgccc gtgtgactca aatccgcgct caagtggaag aaacaacttc 651301 tgaattcgac agagaaaaat tacaagagcg tcttgctaaa cttgctggcg gcgtagctgt 651361 catcaaagtc ggcgctgcga ctgaaactga gctgaaagag cgtaaacttc gcatcgaaga 651421 cgccttgaac tcaactcgcg cagctgttga agaaggcatc gtatccggtg gtggtacagc 651481 gcttgtaaac gtatataaca aagtcgctgc agttgaagct gaaggcgatg ctcaaacagg 651541 tatcaacatc gtgcttcgcg cgcttgaaga gccaatccgt caaatcgcac acaacgctgg 651601 ccttgaagga tctgtcatcg ttgagcgcct caaaaacgaa gaaatcggcg taggcttcaa 651661 cgctgcaact ggcgaatggg taaacatgat cgaaaaaggt atcgttgacc caacaaaagt 651721 tacacgctca gctcttcaaa acgctgcgtc tgtagctgca atgttcttaa caacagaagc 651781 tgttgtcgct gacaagccag aagaaaacgg tggcggcgca ggaatgcctg atatgggcgg 651841 catgggcggt atgggtggaa tgatgtaata aagggatatt aacccttata catcaatgtt 651901 ttaaccgtct taaaaaacta gacaaagcgt gaataaaaaa agagaaggtc tttcatcagt 651961 ttactaaact gttgggagac cttttctcca tattagcggt catatgagca taaatgtcca 652021 tcgtcgtatt tatgtccgaa tgaccaaatt gttgctggat ttctttaatg cctactcctg 652081 cctcaattag taaggaggta tgggtatgcc taaaagagtg gggggtgaca ttctttttat 652141 cccagctttt ttgagcagcc gtttaagtct agtctcaata acctttctta attgcggatg 652201 accatcctcc cgctcaaaaa taaatgatga gtcttgataa atcaatctat ttttaagctt 652261 aatttcattt tgataaattt tatttttttt tagtagattg acatcgtttc atcaattcga 652321 acgatatcaa cagatcctgt tgttttaggt gttagcaatt ggtatttttc aatttgattg 652381 ttaggggtgt atagggtctt tgtgacctgg cttatcattg aaatctgtcc attttaaagc 652441 aagaagttca ccaattctta ggtcggtcta ggcaagtacg gtaaagacca aatggtccat 652501 ttctagcccg tcagattgag cgagctttag aaaatgtgtc agcacctctt tttccaatgc 652561 tttgttgctt cttgggtaat tgaaaatccc cagttgggtt cattttaata atcccttgag 652621 ttttagcttt tcggaaaatc atacggccgc aggcatgaat acctcccaaa caattgtgac 652681 tgtattgctc gttcagttct aacgtgcggt cttcatacat ttttttgtgt tttgctaatc 652741 gggtattgac ccaatactgc gataaaatgc atcattttct tttcactggc ccgtacactg 652801 cttattttta ccccactccg gttgtaaatc ttaagccaac cttttgcaaa tgttttgaag 652861 ggcatatctg actccttaat aaaagtcccg ttgtcgtttt ggagttctac gtgacgggct 652921 gctactgggg cttctttctt tgttttaaat cttcctttgg atatttctag acgttttttg 652981 gttaaagggt caatgcctag tagatatgat aactccacgt cttaccgcat tgcttgagtt 653041 ttgccattta tttgtcccta actaattttt tttcatcaaa ttggtcttta agtgagttta 653101 ataatttttg tttctctcga ctggtcaata attgcccttc atatttcaaa agattggata 653161 aatttgagat ggaatcaatc ctgatggatt ctaaaagctt tgtaaatttc taattttatc 653221 ctggcctact gtgcaacaga ccttcttaat cgagcctaat tttccatcta tttgattggg 653281 gaacaaatgg ctttttaaca agaaagaagt ccaagaatac attgattggt ggtcaattga 653341 ggttaaaagg aaaaagaggg cctgatatat ctttcacttt cgcctaacta gcaaaattta 653401 ataaaacgat aagcgatgtg aggtgaaaat tatgctaagt gataataatt ttgtttccga 653461 aacactggag aatgtacagt atctattgcc aggtgcaaaa gtaatcaaat tgaggggata 653521 cagcagggcc cacaaagtat acaccattgc aaaatccccg gtagaaaagt ggaaggtcgc 653581 cgcaggttta tccggatcag agatagcaat tctgattaga aaaggtcatt ggattggtgc 653641 aagcattcca gctggcggaa ttgtcatcga tattgatgat tcaaaacagg gagagctagt 653701 gaaaggttta ctagatgcgc aaaactttca ttgtcattgt attaggaccc taatgggtgg 653761 cagtttattt ttaaggataa ccaacatggg gaaaagaaaa ttaaacaaat aaccaaattt 653821 tttactcaaa taggtatcat agtcgatgct gggatcgctg gggcaggcta tattgttttc 653881 ccaacaagta acactgagga cgatatatag taactaagag tcctaatgag ttagatgaaa 653941 tacctaatta tctgaggcct gtacggaatt ctgttaatgt aaaggacaac aacactggtg 654001 aaaaatatgt attccctgta ccaatcgaca gagttggtag cagaaatgat actttaaatt 654061 tgctacacat ttgaaagcct ggaaggtgga accatacgaa attagcaagg ccatggaatt 654121 gatttataaa taccttctgc tggataaaaa agatttctct ttggaggaat tttataaact 654181 caccatatat gctatcaaat ggaaactgga acaagctcag tttccattgt atttagaatc 654241 cacaaaaaaa tcgcatcaaa atgttattcc ccagccgttt aagataaaag gaaatgtctt 654301 atataaaacg gtaatcaaga atagcgggga ctttgaagaa tagctcatca tggcgtgtag 654361 gagtgattca cccttttaag aaactgtcta atatcgaaag aaacagtgtt cattatgaac 654421 tagcctcaaa cgataacgga cgcgaaaaaa aggatatagt tcctgctagt gttatatcac 654481 caagcgggag ttgcttttca ttggcggata atgggctagt tgagaaggaa gggcaaaaaa 654541 tgaagctgac agagagacaa cgacgctttt gtgatttctt tacagaaact agaaatacaa 654601 cagaggctac gcgtctagcc ggaaacaaag ggaaaaatct caacagagta gcttctcaaa 654661 acttgtcaaa actagacatt caaactatat agagcaaaga aataatcaac tagaagcgga 654721 gcgcatagca aacattattg aggtaaaaat gttttggaca attattatac gcgatggaat 654781 agttcggtta aagagcgact aaaggcgtct gagtatatta ctaaaacaaa tgcggccttc 654841 aaggaataga ttgaacatac tggtgaaatt aaaacaggga atgaggaaga agctaaattc 654901 gaatgagagt gatctaaggc ttctagaatt gtatatggag gtgtggtaac gtgagcaagc 654961 ttatatagaa ggattaagtg atcaagttta gtgtaatact aggaatgata aggtgttcat 655021 taacgcacat tacaactaaa aataccgtaa atgccctcaa gaggatgata tatccaaagc 655081 aaaaaccttc attctttcat gaatttaaag tattatataa gctactgaaa aagttttgta 655141 taaaaggtat aatgataaag aacattcgtt cttgtatggg gtactttctc tgagaatgaa 655201 aataatgtct tagggtgata taatgacaaa ttttatttta aatgaaaata aacagttatc 655261 attggcaatt gaagatgaga acatagaaaa tttttatata gatggtacag atttagtccg 655321 aaagataatc cgtagatcag gttcaggagt tacatcacgg gttccggtcc ttagcaccca 655381 agatttagaa aacaagaacc ttcatgaatt atacgatgaa tcttggctcc gtatgaaaaa 655441 cagacccaat actgagctca ctactgagag tataaatatt gcggatttat ttagtggatg 655501 tggaggtcta tccttagggg tttgggaggc atgccgtgcc ctggggataa atccaagatt 655561 ttcgtttgct tgtgatctta acgaagctgc cttatctgtg tacgaaaaaa acttttctcc 655621 cgattttagc ttgaatgaat ccatcgaaaa acatattaat ggcgagttag gtgctccatt 655681 aactgttgaa gagcaaagaa taaaagataa ggtgaaaaaa atagatttca ttctagcagg 655741 tcctccttgc caagggcatt ctgatcttaa taaccatact agacgaaaag accctagaaa 655801 cgctttacta atgagagtaa gtagagttat agagttgttc caaccttctt cagtattagt 655861 ggagaatgta ccaggaatta ttcatgataa atctggttct tttaaagaat ttaagaatca 655921 tttaaagaca caaggttatt acttcgatga aatcgtacta aatgctgaaa aactaggtgt 655981 ttcacaagca cgtcgtagat attttatttt tgcttcaaaa actcctgtat cttccttaaa 656041 tcaaataaat gaattttatt caaccaatag taggccaatt agttgggcaa tatcagattt 656101 agtagaaaat gtaggtgatg atatattcaa cactgcttcc gagcattcat tggaaaacaa 656161 aaggagaata gaatatcttt ttgaaaataa cttgtttgaa ttacctaatt cagaaagacc 656221 ggattgtcat cggctaaaac cacattcata caaatctgtg tatggcagaa tgtattggga 656281 tagacctgct cccactataa ccagagggtt tggatcaaca ggtcaaggga gatttgttca 656341 ttctttgtta aagagaacga taactcccca tgaagcagct aggattcagt tcttcccgga 656401 cttttttaac tttggtgacc ttcggaggag acagtatcaa gacgttatcg gtaatgctgt 656461 gccttccaaa ctatcctatt tattagcatt acatcaatta agataaaaag atttgaggtt 656521 gatatctttg aaagttgtta gtttattctc cggcataggc ggaatagagc ttggccttca 656581 tcagtcagga catacaacag aaatattttg tgaggttgat cctttggcaa aagctgtttt 656641 atcaaaaaac ttccctggcg ttaagataga agatgatatt aatgaaatta gagagttacc 656701 aagctgtgat ttagttgcgg cagggtttcc atgccaagat ttaagtcaag ctggaggtaa 656761 agaagggatt gacggatcac gctccggttt agttaagaaa ctatttgaac ttatagaaaa 656821 gaaagaacat gcaaatcgcc ctccatggat actaattgaa aatgtcccat atatgttaag 656881 gttaaaccgt ggtaaagcta tgtcatattt aacatctgtc ctttctgaat taggttatac 656941 ttgggcatat cgaactgttg atgctcgttg ttttggttta ccgcaacgaa gacatagagt 657001 tattttgtta gcctctttat ttgaagatcc aaaagatgtg attttttcac aggatcattc 657061 agaaccagat ttagatggaa agccttctgt tgtggatcat tccaactatt atggttttta 657121 ttggacggaa gggttaagag gtgtcggctg ggcacgtgaa gcagttccac ctataaaatg 657181 cggatcgtct gtaggtatag cctctccacc tgcagtttgg tctccttacg aggatatagt 657241 agggaccatt aatataaggg atgctgagcg cctacaagga ttcccggaag attggacaaa 657301 tatcactact gaaacaggta aggatataaa agaaggtgcc agatggagat tggtgggaaa 657361 tgctgtttcg gtaagggttt ctaaatggat tggtgaaaac ttaagtcagc caaaagggtc 657421 gatatcagat tttgaaggtg aattagtgac caagacttgg ccaagtgcag catgggggta 657481 cggagataaa aagtataaag ttcccgtatc aaaatgggtt gcaaacacag aacaaatagc 657541 tatttcagag tttttaaatc atccattaaa acctttatct gctagggcat taaacggttt 657601 tttaggtaga gcagccaggt gtacaaatgt aaattattcg gatgaattta ttaactcgtt 657661 agaacgttgt aaggataggc aacttcaaaa ggtttaactt ttcacattaa agagagcata 657721 ctaaaaagta tcggagctgg ataaaaccag ctccgttttt tatctttaat tttttttgca 657781 ttattccatc ttttattcga ccagttccat aaactccttt tcaattcttt gggggtttcg 657841 ggtctcggca agactttcat ctaccctgaa gtagaatttg atttttggtt ctgttcctga 657901 aagtcgcagg cacatccagg gatccgactt caagaaaaca tttaagaaca tttgactgtg 657961 gaaggcccat gagttcctca gggccttcca cagtctctcg attccggtca agtaatcctc 658021 aacagtggta accttgacgg aaccaaagct ggccaaattc agaacggaag gcagcgaggg 658081 tctgctgaat cagttctgcc ccttcttttc cctttagtgt taatgagcgc aggccttcct 658141 gaaagtagcc atattcttca atactaagga gagcttcgta tagtgaaatc cttttttctt 658201 atagtaagca catacctcaa ctgcaaggac atccgtctga acagcatcct tgtctcggac 658261 aaagtcgcca atcagatagc catagctctc ttcgtaccca aagaggaaat tatgttctcc 658321 tgtcttgtag tagccattaa tctttctggc aatgaactta aatcccgtta atacaccgat 658381 tgtttcgact ctgaaagagg ttgcaacttc cctcccaagc tccgaggtaa caatcgtttt 658441 aagaacgatc ccattagatg gaagtgttcc tttctttttt atttgggtta agatatagtg 658501 gagcagaagt ggctcggttt gatttccggt taaaaccgta tactcaccat tttcattttt 658561 aacagcaatt ccaagcctgt ctgcatcggg atctgttgca attaaatatc ggcgtcaatt 658621 tgctgccttc cctgatggcc agctcaaacg cggcatgttc ttcagcattt ggactggtga 658681 tagtggaaaa cagagggcag gctgctcctg ttcttttccc accgctacat gcttgtagtt 658741 cattgccgcc aaggccattg cagtagattt gctgtaccat gaagcggcgt aaatacaacc 658801 ttgatgtctg tttcatctta aatatttgag ttttctgaaa tagttcaagg tatgccttgt 658861 ccacctctgc gctatatttt gatcaggccc tttgctagga ggaagctggc cgccatctgg 658921 cccataaact ttatatccat tgtattcagg cgggttatgg ctcgcagtca caacaatacc 658981 ggcaaaacca tgaaggtgac gtactgcaaa cttaacacgg ttgtaggcct taatgactcg 659041 aaaacgtatg cgctggatgc cagtgtcctg gcggcttcca ttataaaagc cgccaaccca 659101 gcagaaactt tccttaacgt atagatgtca tccggtttgt tccagctcca atttccccgc 659161 gcatgcctcc tgttccatat cccaaattcc ttataaaaag catcttccag gtctttctca 659221 ttccttcctg atttacccaa ccccgatttt agctcggtgc aagttgacta aactgtagcc 659281 atttttctgt tttgtttttc cagcctatga ttgacctaca ataaaataac attattgttc 659341 attataatat agtctagagg ttttcgaacg acgactttct gacataaatc gagtgctctt 659401 gtctgattat gtctagttat agttggtttt ttttattttg tctctaaatt tgatgagatc 659461 atggtggcga ggaatttctt tttcgacagc cccaatcagt accaattcga tatttgaatt 659521 ggtctctcaa acaattccat cctctttatt tattatgata caattatatt aattagaaaa 659581 tacatacata ttagcttgtg tgattttatg ggggtaaaat caatgacttt tataaaaaga 659641 ttagaggacg cttatgaaac tctattaggg aattaccctg ccggagtatc tagtaccagt 659701 actagtaagt ataacgaaat acgaaagatt gtttcagaag ccttcttgat cggtgaaaat 659761 gaagtgtatg taacgggaac atcaagaagg attagcaatt tggacactcg gtttgctcaa 659821 ggaaatcaac ggaataaaca tacccggatg gcagttgctt ttatttctat accttctgtg 659881 gacgattcgg aattagatga actaattata agaacgagaa atagtgcaat tacaacctca 659941 tctaaattct gtaacgggga agaaaggggc acgatttttg acggaatatt acttttttta 660001 gtatttgagg gtgaaaccaa agtgtatccg ctagcattct tagttttcga gaacgatttt 660061 gaattaaagg aaaaggctga ggaattgatt ccaggaattg aactcaaaga atacccgcga 660121 gctaatcaat ccccagccca ggaaaataac aaaagcgcta aaaatgaaga tgaggaaagt 660181 gcaaagagct atgtagtctt ccttgatatt gaggaagatg gttctattgt ggaatttgta 660241 gaagataaag acaaaaccta tagaattggt gatatgattt ggacggcttc acatactaat 660301 ggttcatcag ctatcacacg cagactggaa gtaattgaag tcgttgaaaa tcttgtggtg 660361 tgtaagataa aacataaata taatgaacct gttgataaga attcactgct taagtttgta 660421 aatattgaac aagatttgat ttcatttcta gacttacatc caaatgtcca aaatggaagt 660481 gagggatttg tatctgggga cattgttgat gagaacgcta ctacatcatc ggatgactta 660541 ccggaagact ttgaaaataa ctaagcgata aactttaaat aggggaaatg aactgatgga 660601 aatatccaaa caaacttcag atttattatt gagcctagaa aagaaaaaag gcactttacc 660661 aaaattcagc gttttacgca gtattcctag gaataggatt atttatggtg caccaggaac 660721 agggaagagt aattatctag aaagggaagt gggaaagatc tttggtgata atccatatgt 660781 attcacccga gttacttttt tccctggtta tacatatgga caatttatag gtgcttataa 660841 accggttcct atatataaaa aattaagcgg tgaggaagag atatttagtt caaactttag 660901 ggataagatg gaaaactttg agccaatgat tgattatcaa tttgttcctg gcccatttat 660961 cgatgtatta attaaagctc tgaaaaatag atacactaat tttatattaa ttatcgaaga 661021 aattaatcgt gccaatgcag caagtgtttt tggtgatatt tttcaattat tagacagaaa 661081 taaaaacggt gaaagtgatt atcctgttac attcgggccg gacattatga attatttagc 661141 gagaaacgga attaaagatg aaatgattaa gctaccatcc aatttcttta tttgggcaac 661201 tatgaataat gcggatcagg gtgttttacc gctcgatacc gcttttaaga gaaggtggtc 661261 atttgaatat ttagagttgg aaaagtatag aaaggcagtg gactcttgga agctgagcct 661321 cagatataaa ggtcataata aagtaattat gtggaatgat ttccgagaca ttattaataa 661381 gcgtcttaaa ggaaaagtac cagaggataa gctgcttgga ccttttttcc tgaaagaaag 661441 tgaactgtgg aatcagaatg tatttaaaaa taaactgctt tattatttga aggaagatgt 661501 tttcaagcat aatccaacga ttgatttttt aaatgctagt actttctctg agctaattga 661561 aaaatatgat ggctcggata acatttttac ttttgacata gatgattcgt cttttgtgag 661621 tgattaacta tggataagtc aagtaagttc ttctttgaag atcaaaaata caataaagaa 661681 aggattgtac gtgtactcgg tggtaattta gctttactca aaagtaaagg tatattatat 661741 gaagattcta gtggggattt aatatttaac tatgtaggtg ttatatctaa tgggcgcaat 661801 gtaatattca ttttgcctaa atactgtaac aggcacttag atgaacattc aaagcggact 661861 ttgtttaata agttgctgaa gatttttaaa aaatattcag gtttaaataa aagccgggaa 661921 tctgattatt tcgtatcgga gctagatagt gatgaagtct ccgactttat gatagcagat 661981 tatttgctta atgatttctc attgaatggg tattatcaaa aaaaatttac tgaatatgaa 662041 attgatggag aaggaattat agattggagt aagacagtta atgaaattac cccagtattc 662101 tcaaagggag ttccatatta tttcagtact tataatgaag tggtacaaaa agacgagtat 662161 cacttgatag ttaaaattca taaatgggct ttaagtaaat attttaatga tttcggagtc 662221 attttaggtt ttacgggact agaatttgat aaatcctgtg atggtatgaa aattttggac 662281 tacgctgatt tttttggctc agtaataaat aaagaaatcg tgaacacata tgttgatcgt 662341 gacgttaaat tgttaaaggc attgaaaacc gcaattgata gggaagagaa tcagttttct 662401 aaacgaccca ctctttctct gtatggaaca aaatactttc acagagtatg ggaggaagta 662461 tgtaagaccg tattttccca tgttaatgaa tacgtaaaaa agatatcaag gccaaattgg 662521 attaacttta cggatataga ggttaataaa gagaaaaaaa cactagaacc cgatattatt 662581 aaggctttcg aataccgttc aaaagaatac tttttaatat tagatgctaa atattataat 662641 ataaattttg acggaaaaaa gctggagggg aatcctgggg ttgaagatat aactaagcag 662701 ctgttatatg ataaggcact tgaaaaactg tccagaggta aaacaaaaca taatgctttt 662761 ctgtttcctt cctctaattc aaccaatacc tttaaagtat ttggttctgt tgattttgat 662821 tttcttgata tagccgctgt aactcttgtt tatatttctg ctgaacaagt ttataactta 662881 tatcttgaaa ataaaacatt ttccactgat gacttattta aatttgtaag tgaaattaat 662941 aagtcaaaaa aacgacatag cgttataact tcaacattgt atggtaatat gtttttgttt 663001 acaaaaagat taagtgataa aaattagttc tagaaggtta aaagccgata acataatact 663061 tgtcctcggt tttgtcctcc tatagtttta aaaatattta tcagcattaa atgttaagtc 663121 taaaaaacag tattttgagc tggttttttt aatactattt tcaactgtta ttagtcggaa 663181 tgaatgggtt gcatgatgta aaaccgacaa aaaactcttg ataaacaggg gtttgtcggc 663241 aacggacttt tatttttgat gcccttttgg ccatttgcaa attttcaagg cttctcatga 663301 gttcaccgaa cttgtgagaa gcttcttttt tgatgtataa ataaacatgt gtagtgtgta 663361 caagcttaca tggcatttca tttatggacc gcttctctct ctattgcaga caggataccc 663421 tattggtata ctctcatacg acacaaaaaa gacccagtta tctaaataag tagtgccacc 663481 cactcttaga ctgtttcccc tagaaaagca ctgtcaaaga ggaatcctgt taaatcttgt 663541 gcttctttgc ttttttagct aaaagacgat gttttccttg caataaggaa ctcgtctttt 663601 atgttaaata taaagagcga cagaataatg acatctgatc cccaaaaatt cactgtcgat 663661 ggagttagat tcttccaaca gtaccttaat aaaatccgtc ccgacgctat ggagatagac 663721 aacctaatta tcaactctga tattatcaag gaggacttaa tagtgcatgt ctcaaaaatg 663781 atagatcgtt tggctttata tgatttacac agaaaaagaa gcatagataa acatttttct 663841 gctgctttta cagtcgatat caatgataga gaggaatttt acagtgcaaa tatagctgat 663901 gtttcaattg atttgaatga atctagtggt gtttaattga atctcatatt cttcagaaga 663961 accattcaat acttcttgaa caatatttaa agtattcatc agcttcctct actgaaacaa 664021 tatcttcaat gaaatcggaa aagtattcta gttctgttct tgttggaaga actattctta 664081 agtatcctaa agggtctctt ttaaatgaat ataccatgat aaatcagtct ttcctttctg 664141 tttattctta gttaatattg atcgtacaat tgagtcgaca agacaggcta ttgtagattt 664201 acgggcgttc attcactgga taaaagcaaa taaaaaaggg cctgttatca tagtcggagt 664261 aagccttggg ggatgggtta ctaatctaat tgctaccctg gaatcgaaaa ttgatgtagt 664321 ggtatctatc ttttatgcca atcgcctttc ttattcgata tggaacacga tcccaggtaa 664381 atacataaga gaagaattag aacaaaatgg tgtgacctat aatgagttaa taaaatattg 664441 ggatatcaca gatcctagtc aagccttgcc gaaagttaat aaagataacg tactgctgat 664501 ttctgctaaa catgatcaat atattgactt gaaagatgca gattatttat gggaaagttg 664561 ggggagacct acaagatatg tctacaattg tggtcattcc ggtattgttc tttgtcgcaa 664621 aaagctggca aatgatacgc tttcctttat acgagaaaaa ctggtttgat acatttgtag 664681 actttaataa gaaacgaaag gccaactgcg acttcagttg gcctttccta tttataataa 664741 agaaattgag tgagattgct gacagaacta cgtactactc gttttcttta gttgcccttg 664801 ctaatcgttc aacctctccc cgaatcccaa tcgcaggctc ccacgaatca atcaaacgaa 664861 tcgccttctg attagattcc accgctttcg ttttctctcc tttacgatac aacagctgcg 664921 ccattccgta gtgatagtag atcagttcaa cttgattggc gttatgtttg tcatagagca 664981 tttgctcaaa ggcttcttcc gctttttcaa actgatcaca tttcacgtaa gcgacaccca 665041 gattgaaata ggcttctatc gttttttcgc cgccgtatgt ggagctgatt tcatttgccg 665101 cttcgtataa ttgaatggct tctacatgat aacctctcgc aaagcttaag tcaccgcgaa 665161 ccaatagaac tctgtgttga atggtagggg aaatcggttg attttcgatt tcgtttaaaa 665221 ttgtctctgc tttttcctgt tgcccgtctt ttaaaaacag ccttgctttg agtgcatgtc 665281 cccaaacctt tagatcatag gcatcgtgag cgtctgattg ttcaagaatc ttcagcccgg 665341 cttctatttg ctgaagcgct ccgtctaaat cattgacttc catcaatgcc cagcctgagg 665401 tgtcgattcg gaagtacgct tctcgtgtgt gttggcctaa gtgatgggcg gcgtcggccg 665461 ctttgcgtcc gtattcgatt cgcaggggca ggttgattct gcttagaaaa tggctaatgc 665521 gggtgatgag ttcgattagg atttcttttt gttcagtttc acttgcccat tggatgacct 665581 ttaagatgtt tggccattct tgtttcattt gatctaagtt ccgtcccagc aggtagctcc 665641 aatagataga gttgggctgt tcccgcttta aatgggtttc ggcataatca atataatagt 665701 gcgcccagcg attgcgggct tctttttcat attcgtgctg ttcggacaag tgctgttctc 665761 cgtaagcgac aacggtttgg tgcgctaagt attgtgtcct gccttggctt cgttccggct 665821 gaatcagcgc atatgaccgc atttgttcca tagcgtaatg aaaacggcgg gcgtctaatc 665881 cggctgctgc cgccaggctt ttttcatcag gcggcttgct gaaaaagcaa agcgtctgcc 665941 agagctttcg cgtatcttca ttgcatctat cccaggtgcg gccaaagagg aattcaaaca 666001 attccagcag tgagtagcct gcttttccaa gctcatgaat cagctgctga gcggggatgt 666061 catcgtctga catataggca atgctgagtg ccatggcttt cgggtttccg gcagtcgctg 666121 aaatgaattc gtttttcagg tcagatgata gatgtaacag ctgctccagc ttttcccgtt 666181 tacgtgggag gttgcatgtt tgtaagcagt gatgcacttc ttgttgaaaa aattcgtggg 666241 catctgtttg gtcaagaccg cttagctgaa tggctgtcat ttctccgaag ctttcccgat 666301 aagtttgctt tacgttttcc cgcgctgtaa ggagaacttt tacgccttgc ggaaggctgg 666361 tgataaattc atgaatgtca cgttctgcag tatcaatgct gtcaacgatc agcaggatcg 666421 gtttttctct agtgtaattg gctaacgcat tgcggacgac aaaccgtttt acattgattg 666481 atttatcgat ttgttctttg cgtccgagct gataggcgat cgtatttaaa aaatcgctaa 666541 agcttaatcc tttccaatca gcgctgaccc agatgatgct gttgaatgcc ggccaaactg 666601 aagtatcgtc gacacaggaa taggcggctt caagagcaat tgtggttttt cccatgccgg 666661 cccagccggt gattaaacag actggtgatg gagaaagcat ccattgccgt atcgcttcca 666721 tatcaaagct gcgtccgata aagcgtccgg accagcgtga gggtaaatta tgcgtgatgg 666781 gctgttctgt aagcgcattc gtttcttggc cgggtctgtc atgaaacagc cgttttacta 666841 cattttcaat ttcgccttca ctcggagccc cgaataatcc gtcttttcgc agtattttcg 666901 cttttttcaa acaggatgct gcccatacag gcaatgcggg tttgatgact gggatagtgg 666961 tggcttccag caagtcggtc aaccactcga tatccaagtc ggtcttttcg agaatgatcc 667021 agatcattcc gaacagtttt ccgtcgtcga ttcttccggg aatgtagttt gcccccatct 667081 gtccgatcca gcttttgatc gtgtttgggg agactcccag ctggagtgcg attttatcta 667141 tgtaagactg tcctgttttt tcattctttt tccttctgac tttataatca ggatgaagtt 667201 ttagcgtttt gacgccaggt gccagcattt gtgcaaattg ttttcggttt tcaagttcag 667261 ccataagcct gcacctccta ttagtactat tttatcaatc cagcgttttt tgtatatgaa 667321 aaaataaaag tacagtgccg ctgtcctttt atacagcagg aaaggctgtt gaacgtgtta 667381 aaaagcagat aaaatggggg cagtaacaga gaaaacaaaa atgtatgcac ttacatttta 667441 ttttctaaag aaaggaactt gccaaatgac tcacacagta cctcaaaaca tgaaagcggc 667501 tgttatgcac aacacaagag agatcaaaat tgaaacattg cctgtgcctg atatcaatca 667561 tgatgaagtg ttgattaagg tgatggctgt cggaatttgc ggatctgatc tgcattacta 667621 tacaaatggc cgaataggca actatgttgt ggaaaaacca tttatccttg ggcatgaatg 667681 tgcgggtgaa attgccgctg tcggatcatc tgtcgatcaa ttcaaggtgg gagaccgcgt 667741 cgctgtagag ccgggtgtta cgtgcggacg ctgtgaggcg tgcaaagaag gacgctataa 667801 tctttgcccg gatgtacagt ttttggctac accgccggta gacggtgcgt ttgtccaata 667861 tattaaaatg cgtcaggact ttgttttttt aatcccagac tcactttctt atgaagaagc 667921 tgctttgatc gagccgtttt ctgtcggtat ccatgcggcg gccagaacga agctacagcc 667981 cggatcaacg attgcgatta tggggatggg ccctgttggg ttaatggctg ttgccgcagc 668041 taaagcattt ggggcaggca caatcattgt caccgactta gagccgctgc ggttagaagc 668101 tgcgaaaaaa atgggagcga ctcacattat taatatacgt gaacaggatg cacttgaaga 668161 gattaaaacg atcacgaatg atagaggcgt tgatgttgct tgggaaacag cagggaatcc 668221 agcggcattg caatccgcac tggcttctgt gcgccggggc ggaaaattgg cgattgtcgg 668281 tttgccttca cagaacgaga ttccgctcaa cgtgccgttt attgcggata atgagattga 668341 tatttacggg atcttccgtt atgccaatac gtatccaaag ggaatcgaat ttcttgcttc 668401 aggcattgtg gacacgaagc atctagtaac ggaccaatat tcgctggagc agacgcaaga 668461 tgcgatggag cgggcgcttc aatttaagaa tgaatgttta aaagtgatgg tgtatccaaa 668521 tcgctgagtg aacagggagg atcttcgtat tctccctctt gtttactgga aatgaaaacg 668581 gattcttggg gtgggaaatg atgattggaa cagaaaaagt aacggcattg aaggcgaagc 668641 atcagtcaaa atccagcacc ggcctgtcct ggtttgaacg aatcggttat ggattcggcg 668701 atatgtcgta taatattatc tttcagtttg taaacgcata cttattattt tattatacag 668761 acgtcggcgg cattcagcct gcggtaatcg caactttgtt tcttgttgtg cgtgtgctgg 668821 atgctatttt tgacccgatc atgggattga ttttagataa aacgaataca aggtggggaa 668881 aagcaaggcc atatttgctg tgggtggcat ttccttttgc gctattcaca ttcttatgtt 668941 tcacgacgcc tcatttcggt gagaccggaa atatggtata tgcgtatgtc acttatattc 669001 tgcttgggat gtcctttagt atgcaaacga tcccggtgaa cagcttaacg gggcggatga 669061 cgaattcggt ggaggaacga acggttctga ccacaacccg gatgattttg gtgtatatcg 669121 gcattctttt atccatttcc tgtgcgacac cgcttgcaac tgctatcgga ggagaggatc 669181 aggcgtttgg atttcagatg acggcgctca tctatgcggc tgtcagcatc gttttgaatc 669241 tatttagttt ctttactgta cgggagcgga ttcagcctaa aaagagaaaa aaacaaggga 669301 tcaaaaagac gttatccgtt ttattcaaaa acaaaccctt gctcatgtta atttcatcat 669361 ttttggcttt tgcgatcggg tttaatatta agctcagcac gatggtgtat tattttacgt 669421 ataacgtaaa ccataaagag ttcgtgttta tgggcaccgt tttatttttc ggggcagcgc 669481 tgatcagcaa tttgtttatt cctttctttt ctgagaagtg gggcagaaaa caagtcatga 669541 ttatcacggc agctctatcg cttatttctt atgccggcct gcattttacg ccgtattctt 669601 caattccact cattttcatt tggcttttcg cttcgggatt tttcacaacg cctttaaata 669661 cgcttgcttg gggaatggtt gcggattgcg tcgattatgc ggaatggaaa accggaattc 669721 gcgcggatgg tgttgtgatt tcgagcatga gctttattaa taagctgggt gttgcgttag 669781 ccgggtcatt ttcggccatt tatttaggaa tcgccgggta tgtggcgaat acagaccaga 669841 cagttgcgtc gttgaatgcg attaaaaata tgaatgcttt gattccggga tttttcattt 669901 tgctttctat tattcttatc gccttctatc ctttaacgga aaaaagatat aaacacatca 669961 tctctgagct ggagcaaagg tctgcgagat aaatagatgt aaaattttta atattcaatg 670021 ttgtatttat ggcaaaaagt aatatactga gactgtaatc tagactttat aaatgagtgt 670081 gataatatgc gtagtcattc tgtagtttgt attggggaat tgttgattga tttcttttgt 670141 accgatgttg acgttgattt aatggaaggg cgccaattcc tgaaaagtgc cggcggggca 670201 ccggcgaatg tgtcggcagc gattgccaag ctgggcggag acgccgcttt cagcggaaaa 670261 gtaggaaagg atccgtttgg gtattttctg aagcgaacat tggacgctgt acatgtcgat 670321 acctctatgc tggtgatgga tgagaaagcg cctacaacgc ttgcttttgt ttcattaaaa 670381 caaaatggag agcgtgactt tgtttttaat agaggcgcgg acgctttgtt tacgctggag 670441 gacattgacc aggaaaaact aaacgaagcg aaaatccttc atttcggctc tgcgacggca 670501 ctgttatcgg atccgttttg ctcagcctat ttacggttga tgtcgattgc gaaagacaat 670561 ggacagttta tttcgtttga ccctaactac cgtgaagatt tatggagggg aagagtctca 670621 gagtttgtaa gtgttgcgaa aaaagcgatc gctgtaagtg attttgtgaa agtcagtgac 670681 gaggaacttg agattatcag cggtgtgaag gatcatgaaa agggagttgc gatccttcat 670741 gagatcggag ccaacattgt cgctgtgaca cttgggaaaa gcggaacgct tctttccaat 670801 ggaaaagacc gtgaaatcat tccaagcatt ccggtgacat caattgactc aacaggggcg 670861 ggagatgctt ttgtcggtgc ggctttatat caattggcaa acacggatca gattcaatct 670921 gtagatgctg attttgtgaa actgcgtgag attgtggcgt ttgccaataa ggtcggagct 670981 cttgtgtgca ctaaaattgg agcgattgat gcactgccga gtttggatga gattggagtt 671041 tctttgtaaa tcattgaaga tgtttcttga aagtctttgg acttttgggg gcatcttttt 671101 ttattgctta catttttgtt caggtaaaaa gttgtatatt ttttgtttga aatgtcattt 671161 tttattaaaa aagtgaaact tttaacgata ataaatagta tatgtaacaa gggttaccga 671221 attagcttta ggaggaacga tataatgagt ataattggaa gatttaaaga tattatgtct 671281 gcgaatatca atgctttatt ggacaaggct gaaaatccgg agaaaatggt agatcaatat 671341 ttaagaaata tgaatagcga tttggctaag gttaaggcag aaacagcagc tgttatggct 671401 gaggagcaga gagcaaaaag agaatatcac gaatgccagg cggatatgga aaagatggaa 671461 agctatgcaa tgaaggcgct gcaagccggg aatgagagcg atgcgagaaa atttcttgaa 671521 agaaaaacat ctttggagtc aaagctttct gagctgcagg cggcgaatca aattgctgca 671581 accaatgccg cacagatgag aaagatgcat gacaaattgg tatctgacat tggagagctg 671641 gaagcacgca aaaatatgat caaggcgaag tgggcagtag cgaaaacgca agaaagaatg 671701 aacaaactgg gcgcttctgt ttcaagtaca agccaatcaa tgtctgcatt cggccgaatg 671761 gaggacaaag taaataaggc acttgatcag gccaatgcaa tggctgaact gaacagcgct 671821 ccgcaggatg atatggctga tctgtctgca aagtatgaca ctggcggttc aagccaggtt 671881 gatgatgaac ttgcggcgtt aaaagcgaaa atgatgctcg ataagtaata cataggaggc 671941 cgcagctttc ggctgcggcg tcattttatc ataaaatgtg agagggaacg gtaatgataa 672001 tatcttataa gtgtccgaac tgcggcagtg atatggcatt tgacagtgaa accggctcgt 672061 tatcctgcag cagctgcgga agacaggaca atattgaaag ccttccgaaa gaaaacattg 672121 cggcacggtt ttctgatgat gaagcaaaag aatatcaatg taaaaactgc ggtgccgttt 672181 tgatcacgga agctgaaacg acagcaacga cgtgcagctt ctgcggaggt gctgcaatac 672241 ttgccgatcg tttatcagga catttggcgc cggcgaaggt cattccattt acaatcagca 672301 agcaagaagc ggagcaggca tttcgaaagt ggtgcaaaaa aggccttctg acaccaagag 672361 gtttcatgtc tgctgatcgt atcaaaagca tcaccggcat gtatattcca ttttggatgt 672421 ttgatttaaa tagtgaagta caggtgagag caaactgtac cagagtccat caatatgaag 672481 aaggggatta tatttgcacg gaaacagagc actttgaagc gtttcgtgat atcaatctcg 672541 attatttgaa aatccctgtc gatgcctctg aaaaaatgaa agacgaatta atggacaaat 672601 tggagcctta ttcatacgaa gagctgaagg actttcaaac ggcatatttg gccggttata 672661 ttgcggaaaa gtacaattat accgatgagg agctttttcc gagggcaaaa gagaaaatca 672721 gcagttatat agattcatac atccattcta ctttttccgg atatacgtca gtcaatgtga 672781 gggacaaaca tattcacacg aaaaacgtga acagctttta cgttttgctt cctgtttgga 672841 tggtcagtta cgattatgaa agagcggagc atatctttgc gatgaacggg caaacaggaa 672901 aggtcgttgg aaagccgccg atcagtcgag gaaaagtggc tgcatggttt agcggaatag 672961 caggcgggac atttcttgcg ttgaagctcg tctcattgat gatgggaggc ggattttgat 673021 gcgtggattt tttgggaaag cgatctttgt tgtgctggct gttttcatca tgatgccttt 673081 actgggtatc gaagcggtaa gagcctctga attgcagcag catgtgtacg atcgcgctca 673141 tctattgtca aaagcggaga tcggaaaact tgaatctctc tcggcaaagc tgggtgcaaa 673201 gagggacact gatttcatca ttattacgac caaaagcaca aacggtgaag atattgcaga 673261 ctataccggc gatttttatg atcgttacgg aaaaggcagt acagccattc tgacgattga 673321 tatgacaaac agagaagtgt ttatcgcagg ctttaaaaaa gccgaacagt atttggacaa 673381 cagcaggctc aatagcatca gaaatacgat ttcatctgat ttatccaatg aaaattattt 673441 tgaagctttt gagacatata ttcagctttc ctataaagat atgggcataa aaccgggagt 673501 aaaccctgac aacatattct ttacatggtg gtttcagctg attgctgcca tcgcagtcgg 673561 gggaattgcg gtttcaatca tgctttatca tgcaggcggc aaagtaacgg ttaatggaag 673621 tacatatatg gatcagcgta cgtctgatgt gattgatcaa tacgacactt atattagaac 673681 gactgtaaca agagaaagaa aaccatcaga taaagacagc ggcagcgatg gcggtgttac 673741 gaaaggcggc acgtcataca gtgggagccg gggcagtttt taaatgtaag aaatagagaa 673801 agggagaggc gtaatgtcgt ttttcagaaa tcaattagcg aatgtagtag agtgggaaga 673861 atttagagat gatatgattt tttataaatg gaacaatcgt gaaatcaaaa aagggagccg 673921 tttaatcatt cgtcccggac aggatgctgt ctttttgaac aatgggcggg ttgaaggagt 673981 ctttcaagat gatggcgatt atgatattga atcagaaatt attccattcc tttcaacgtt 674041 aaagggcttt aagtttggct ttaacagcgg catgcgagct gaggtgctgt ttgtcaatac 674101 gaaggaattt accgtaagat ggggaacaaa acaggcgata aatattccgg cagcgggaat 674161 gccaggcggg atgcccattc gcgcaaacgg cacatttaat ttcaaggtgc aggactatat 674221 cagcctgatt gataaaatcg ctggcgtgaa agatcaatat tttgtagagg atattaaaac 674281 ccgtatcatt tctattctgg atcagcttct catgaagtgg atcacaagag aagggaaaga 674341 tatgtttaat cttcaagcaa acgcttttga tattgccaag ggaattcaag aggacttaga 674401 tatgcaatta ataagcgacg ggatgacggt cactggtttt caaatcatga gctttaatta 674461 tcctcaagag gttcaagata tgattacaaa gaacgcttcc tacggtatgg ttggggatgt 674521 gaacagatac cagcaaatat caatgacgga tggaatggca tccggaaaga tgagcggaag 674581 cggagcggct tcggatatgg ctggaatgat gatgggaatg aatatggcca atcagatgat 674641 gaaccaaatg aatcagaatc agcaggcaca gtcatcaggc ccacagtcaa ctggcagcgg 674701 aagcaaaccg aatttctgtc caaactgcgg aacaaaaacg ggcgaagcca atttttgtcc 674761 gaattgcggc cagaagcttg tataagaatc atacagtgaa aagtccggag tgatcagcac 674821 tcgggacttt tttatttagg agaataagca ttacctattg cttgctcctg aacaggccat 674881 tttcgagccc ccgcttggat aattcccagc agcaattgac gacgttcctt tattgaattg 674941 acggcaattt gaaatgtttg ctttgataaa gccggtatgc ctgattgttg aagctttgag 675001 atgtctggtt ctggcggcgc ttgttctgca ggatggatat aggcagtatg aacggtatcc 675061 agatagtttt tgatacttga gcgcgcttct ttgatatgaa gctgattcgg ctgatattgt 675121 tcaggaattc cgtatttgaa aatggttaga gcctcatcca atacagcaac agctataatg 675181 gatgattcct gatgctgcgt gctgtggtaa aaatgaagga tggggaaggc gttatgctga 675241 gcggtcagct ttcccagttc tgatgaggca gcgacaagaa gaaaatcaat gtcgtgaaaa 675301 tctttgccat tccatgcatt atggacgatt tcagttccgt catgccctag acttaataca 675361 ctttgggcaa aggagcgttt ttgattaacc gcactcaaga cggaaatcaa atacgtgaca 675421 gaaaatgtga tggtaagcag tccttgagct gtttcaataa tcgtgacaag cttccatagg 675481 cctccgttcg gagcgaggtc gccatttcct aatgtaaaca tgacatagcc ggaaaaataa 675541 attcggtctg accaggaagc cggttctttt gattgagttt ccataagtga gtgagggtca 675601 ctcgagtaaa tcaaaaccca cccgctccaa aatagactga tccatatcac taacgtcagg 675661 cataacagca gaggaccagc catacttaga acctttgcgt ggtcaccgct gattttgcgg 675721 cagcccttcc acagccaggc agacaggcat cttgtgatcg ggccggcacc gctctctaac 675781 cataacgtgg tccataaaaa atcaatcatc cccgctgtca ataataaaag gcctgcaatg 675841 atataaccct cattcatttt ggttgcctcc cttaagtcag ccttctttta ttttcttctc 675901 tatttccttt tatcctgagt ctgaaacaat tgaacgaatg tttgatttta cagagaaaaa 675961 taggtgggag ttacccaaca cttactcatt tttcaatatg aacagaaaat cacaagattt 676021 ttgacttgat tcacacattt tcatgaagaa aaacgttcat tttccccttg aattggtgat 676081 tttcctttta tagagtaaaa aattttcaga aatttatatt gactgaaagc gtttttataa 676141 ttatgataat atcagatata acaaaaatgt cactataaca tcactacaat tgaactatta 676201 agtgactaat aaataccaaa tgaacgaggt tatgcacaaa gaaatgacca ttgttctttt 676261 aacgagaaat gaaatcgctt ccatagggat tgacatgcta agaagaaggg aaggttatga 676321 ggttattgga taaaaacatg aacaactatt ttctgaagcc tgcttacgaa atgtgaggaa 676381 ggcagcagcc ctggaataag tttttgacat acgcattttg aaaaagactg ggggaaacag 676441 tatgaataaa caaggaaatc aaatgtcatt tttacgtaca attattttag tctccacttt 676501 cggcgggctt ctttttggct atgataccgg tgtgctcaat ggagctttgc cgtatatggg 676561 agagccggat cagcttaatc tcaatgcctt cacagaaggc cttgtcacca gttcacttct 676621 ttttggagcg gcactgggtg ctgtgtttgg cggcaggatg tctgatttta acggccgccg 676681 caaaaatatt ttgttcctcg ctgttatatt ttttatttca acgattgggt gtacgtttgc 676741 accaaatgtt acggtcatga ttatttcccg ttttgtgctc ggtattgcgg ttgggggtgc 676801 atccgtaacg gtgcctgcct atttagcaga gatgtctcct gtggaaagca ggggacggat 676861 ggtgacgcag aacgaattga tgattgtatc aggacagctt ttggcctttg tttttaatgc 676921 gatccttgga acaacaatgg gagacaactc ccatgtgtgg aggtttatgc tggtcattgc 676981 gtcacttcca gccttgttcc tgtttttcgg catgatcaga atgcccgaga gtccccgttg 677041 gcttgtttct aaaggaagaa aagaagatgc tttgcgtgta ttgaaaaaaa tcagggacga 677101 aaaacgggca gcagctgagc tgcaagaaat tgaattcgct ttcaaaaaag aagaccagct 677161 tgaaaaagcg acatttaaag atctttcagt cccatgggtg cgccgtattg tgtttattgg 677221 attagggatt gcgattgtac agcaaattac aggtgtgaat tcgattatgt attatgggac 677281 tgaaattcta agaaattccg gtttccaaac ggaagccgct ttaatcggaa atattgcgaa 677341 tggcgtgatt tcggtattgg caacattcgt cggaatctgg ctgctgggaa gagtggggcg 677401 ccggccgatg ctgatgacag gcttgatcgg tacgacaaca gcattattgc taatcgggat 677461 attctcactt gtacttgaag gatcaccggc acttccgtat gtagtcctgt cattaacggt 677521 cacatttctt gcttttcagc agggcgccat ttcaccagtg acttggctga tgctatctga 677581 aattttcccg cttcgccttc gcggactggg aatgggtgtt acggtattct gtctgtggat 677641 ggtgaatttt gcagtcagtt tcacgtttcc gatattgctg gcagctatcg ggctgtccac 677701 aacgttcttt atcttcgttg gattaggaat ttgctctgtc ttgtttgtga agaggttttt 677761 gccggaaacg aaagggcttt cgcttgagca gctggaggaa aacttccgcg cttatgatca 677821 cagcggggca aagaaggatt ctggggctga agtgattgga taatttaaaa aagaatccgc 677881 acccgagtgc ggattctttt tggtttcaaa ttagttaggt ctaacaagga ttttgacttg 677941 gcttttctct ttaataagag ccccgaagcc ttcctcgatc aaatcatcta gtacgatttt 678001 tttcgttacg agtttgtcgg ctgagaaata gccttctttc attaatgaca atacagccgg 678061 gaagatgtcg cggtatccga taattccttt tactgtacgt tctttgatta cgatatcgtt 678121 cggatggatt tcagcacctt tttcccaaat gctgacgatg acggtttcac cggcaattgt 678181 agtggactgg atggcttgtc gtaacaccac tgggacacca gtgacttcga atgctacgtc 678241 aacaccgcct cctgtacgtt ctgcaatctc agcgactaca tcgtctgttt tagacggatc 678301 aacgatgatc gcgccaagct cctcagcttt ttgctggcgt tcaggagaaa gctcaacagc 678361 gtaaatatca gttgcaccgg cagccttcag cgcttcaatg acaagaagtc cgatcgggcc 678421 gcagccgaat acagccgctt tgtcgcctgc tttgagtttg cttgagcgga cagcgtatag 678481 agcaactgca gaaggttcaa cgagcgcgcc ttgttcatat gataattcat caggaagttt 678541 gaacaaaagc tcttcatcca cagagacgta ttcagagaaa ccgccgcctc cgccggctaa 678601 gccgaggaat cccatttgtt catcaaggtt gtaggcgcct tggtggccgt gtgtagcaaa 678661 aatcggctcg actacaacgc ggtctccaac tttataattt tcaacgcctt ctccgacttc 678721 gacaacttca ccggagaatt catgccccat tgtgacaggt gccgtttcat ttgttaatgg 678781 gtgcggtttg tcaaccggaa taaagatcgg gccgcccaga tattcgtgta aatcacttcc 678841 gcagatgccg caccatttga ctttgatctt tacttttccc ggctccgttt ttggctcttc 678901 gatatgttca atacggatat ccttttggtt atgccatctt gctgccttca tggattacca 678961 ctcctataac ttttgatgtg agtaattccg caccggtcaa tatgaactgt tcacaaaatc 679021 gccattttta aaaccaaaaa agaaatgaaa tttttatata atataatcta cgtttttttg 679081 aaaaaaagaa actttaaaga aaaaagggtc tcgcacactc ttttttcttt atatgagagt 679141 atcaatcgtt tacatagcta tgaatttggt ttgaacaata cggtaatggt tcgttcatat 679201 tgaatgcgac aactactcta tcaataatta taactctaat actgctatta taataggata 679261 atcttccatg gtttatttta gcagaggtaa cttttttgac tttgtaacat tactgtaagg 679321 atattgaaat aaaaaatagc tggttgatcg tgtataatct tcctagatgt taacaaacag 679381 ggggacgaaa tgttgaagaa agtcatttta gccgctttta tcttagtagg aagtactttg 679441 ggagctttta gtttttcatc agatgccagt gcgaaacatg tgaacggaaa tattacttgg 679501 tataatggag tcgggaaaaa aggctcttca ggtaagaaac ttggacattg ggattgtgcg 679561 accaaaatcg gatttgatgt tcctagaaac gggacaaaaa tcagagctta tgcaaaagcg 679621 aagcctaaaa aggtgattac ggtttataaa aatgatgttg gcagaatgcc taatgcagtg 679681 ctggatgtta gccctaaagc gtttaaagcg cttggatacc cattaagcaa aggtaaagta 679741 gcggggcatt acagctatta atgtacatat ataatctgga aagcaagaag tcacattctt 679801 gctttttcta ttggtggaga taaaagatga aaaaaagaat catattatta ttagcagtga 679861 taatagcggc agctgccgcg ggggttgcgt tttatgttgc aaaggataaa ggccatgaga 679921 aggctgctga tgtttcagtc aataccgaaa gcggtgatga gctgctggtt tcaattacag 679981 atacggatct gctgacaaag tattatgaaa atgacaaggt gatccatgag gagaagctga 680041 ccagctatcc ggcatttgcc ttggatcaaa aacagcaggt gctctattat acgggcaata 680101 atgaacagaa tgaaatgagg ctttttaaat tggatctgaa gtctcataaa aaaacgatgc 680161 tttataaagg cgcggagagt gcggacagtt tatttttatc aaaggaccgt tcaaccatct 680221 atttccgctt aggaaaagcg gacgaaagca attttcgaat cgccgctttt gatctgaaga 680281 cgaaaaagta taaaaatctt tatcctgccg ctaatgatca ggatgacacc gtcagcagct 680341 tcttttataa ccaaaaaaac gattcatttg cattgcttca ttattctgta gaagaagact 680401 acaagaaaac agatgaagca aacgaaaagg gcatcgaccc tgaaccgaca acgattcatt 680461 ttgcggaagg ccgccaaaat aaatttaatg agctgaaaag cctgaaccaa tttatcagcg 680521 atattgctgt ttctgatgat gataaacgta ttttattcac atcatatacg caaaaaggaa 680581 cggagcaaac cgcttctatt caaatgctca atgcggatac gaaaaaatat gaaagcatca 680641 tctcaaatca aaaatcattt aagctgttaa ttgacgcaca gcctcagttt tctaaggatg 680701 ggaagaacat ttattttctt gccgaagcca agggggctaa aaagctgaag gacgaaacag 680761 ggcgtgaagc taaggtgcgg acgatttatt cctatagcct tgagaataag accttcaaaa 680821 aagtatggga aaatccgaac ggcatcatca acagcttttt tgtgattaac taataaaaac 680881 cactcggcat gagctgagtg gcttttttaa tggatgaggt gcagggctaa tgatccgagc 680941 catttaaaga tatgaatcag aggtaccgac aaaaacagaa gttcaacata tgagttcatt 681001 gcaacattca gctttttgaa cgcagctctt tttttcaagt ctttttgctg ctggtttgag 681061 atcacgttat cactcctctt atatccatat tataccatta aaacagacaa aaaagcccta 681121 aacgtttaca gttttgggct tctttcttcg tatttggcct cttgcaatga gaggctttta 681181 ttctgaaata tagaattttg tctccgttcg gggtttgttt gcttgcggga gactgcattt 681241 gttataggga agaactagct tgttttcgtt tggctgttgt tttggagatt cactaatgaa 681301 cggatgccgt cgaccatttt acttccgcac aaagggcaca atggcgtatc actgctggcg 681361 aagttttttc gggtccagcc attacagtct tcttttgtgc attcccaagt actcacatct 681421 tcctttggca gcggttcttg atttcgtttg ttatagtaag acataaagtc acttcttccc 681481 tcatgtattt tactgcacat ttcctattgt ctcatacttt tccctaatct cctaattcct 681541 ttttctttat gactttccaa taaccccatc taaaaaggag aggagtgtgc tgttaaaagc 681601 atctggctct tctaaaaacg ggcaatggct gcttttagga aaggtaacga gtgtcgcgtt 681661 tggaatattg ctgcgcaagt gttccccagc tgctgtagag aaaaatttct tgtcttcccc 681721 gaagcacagc aatgccggca cattgatgtt ttggagggtg ccccggtaat cagcggccgt 681781 ttggttaaat aaaatcgtgc tagaaatggc agccggctgt ttgaggattt ctgccagcat 681841 ccattctgtt tcggtctcgg caggcggttc tgcgaacata ttctggatga agctttcgta 681901 gaaaggcagc gggtcagttt gaatggcgtg catcgctgtt tttaagccgt caaaatcaaa 681961 tggaccatgt tcccagccct cccattgata gtccgaagcg gattgatcga tgatcacagc 682021 ggcttgaatg ttatcattcc caaactgatt gagataatcc catacgacaa aagcacccat 682081 tgaccagccg gcaagaacga catgatcaag ctccattgca tttagaaatt cccttatgtc 682141 acgggcatat tgggaaatgg tgtggccgtg aagcactttg tcagattcgc cgtgtcctct 682201 aagatcaaga cgaatacatt gataattggc agaaagcacc gaaaattgtt tgtggaaaaa 682261 ttgtccgctc atcagcaccc catgtataaa caggatcggc gtcccgctcc cgtgtgtttc 682321 atagtaaagg cgtgtctgat cttctaatat gatgtatggc atgtttctcc tcctttagtt 682381 tccatcatga gtatggctgg ctgctgttga gctgatgatg gcagctgtcg cggctgcctg 682441 ctgcgcttga atgactgttt cgatagcggt gtatagtcct gattccatca gcagattttt 682501 ctccatatgc tcactgagat agaggctgac agcaatttta aagttcattt ccttttgcca 682561 tttaaaagct ttttcctggt ttaattcgtc agtgatgcac aaaacggttt tgatatctgg 682621 ctcttccaga aatgtgagga gagcaaggtc tggataatga taatcctttg tttttttgac 682681 agattcagtg atcgattgat atatctgttt gcaagcggaa acaagcattt cgggctcttt 682741 ttcactttgc aaggccagaa tatggctgac ctgatgtaag tactgtcctt ttttaaagcc 682801 gttggctgcc agcagttgat agcatgtttc cgccttctgt agcgcctgca aaccttttcc 682861 gttttctcca agcagtacgg caagcggaac attctgagtt gaagtgagga aataatgatt 682921 tttcttcatc tgctgataaa cagctagccc catgttcatc tgttcttttt ggtttgtcgt 682981 ttcagatttg ccggtgagca agatcagagc ggaaaggtat gtgaacatat cccgcttata 683041 ccctagcttc accatttcat tgtatacatc gatgaaagtc tgaaatgttt gttttgcctc 683101 atgctgaaaa tgaatgtcca gaatagatgc aacagtaaag cggtggtgtg aattgagtgt 683161 tgagaagctg ccgatgtttg atttgatata gctgctcaaa tcataaaagc gctgaaaatc 683221 aaactctctt ttattcacaa tatatgcaga agaaatgagc attaatatct gatcgtgtga 683281 aactttccat tttaattttg tttttaattc agcataaatg gaaatgtaat gctttgtttt 683341 ttcatgtaga tcgtgtgtga gcataaaaag cagctccttt tgttgttttt acgtaatacg 683401 ataaataggg ccaaaggttt cataaagaaa aaacttgcct gctagaggca agtttgtcgg 683461 gttatttatg gggatcagtt atatccatcg gtctcatcat gtcatagtct tcatgctcta 683521 gaatatggca atgccatacg tatcgtccgc tgtacggacc gaatgtcgcc gcgattctca 683581 ggacttcacc tgcatgcgct tgaatggtgt ctttccagcc cttttcactt ggcggcggcg 683641 ggacagccgg accggtatag gacaattccc cgctttcttg ataacgggcg atatcaaacg 683701 gccgccggtc taatacacgg aaggagacta gatgcaggtg gatcggatgt gttccgcgtg 683761 tcgggttgat aatggaccat atttcagttg tgccgacttt tggtgtttct gtgacgggat 683821 cgtgccagcg tttgttatta agcagaagga cgggtctgcc gtattcgtcc tgggtgcctg 683881 ccagttttaa cgttctgatg ttttgtattc tttcatgctg taccgaaggg tatgaggcga 683941 ggtacttcgg ctttctgctt tcgtcttttt gtgccaatgg ttttgtgact ctgaattgca 684001 tgatattcgc atctgtttca ggattgacgt caccgccgca gcccgcgctg tttgccaaaa 684061 tgatcgattc tccttcatat gctgtgaagt caatgatgat atcgtaacgt tcagcaggcg 684121 caaggctgaa agaattcagt ttaacagatc gcggcaggag ccctccatct gaaccaatct 684181 gaataaaatc tccgccatta tcgagtgaca ggttataggt tcttgtattg gaggcgttga 684241 tgacacggaa tcggtatttc cttggctcga cttccaagta tggccatacc ttcccgttga 684301 cgagtatggt ttctccgcaa aaagccggaa cgattgaagg attaggcagt gacggagaag 684361 ggttttccgg tgcgctcgga taaaacaaag aaccatcctc attgatcgtg cggtctgtga 684421 taagaagcgg cacatcgtat tcgtctgaag gcagttttaa gcgtttttcc tttgggtcat 684481 gaatgatata tgcaccgaca agtccggcat agacatttag cctggtgagc gccatggcgt 684541 gatcgtgata ccacaatata gccccgcgct gctggtttgg ataatgataa acctctcttt 684601 tgaaataagg tcctgtttgt tcaaagtctt tggaaaacca agcctccgga tacccgtcac 684661 tatcatctgg cgtgacgccg ccgtgtaaat gaacaacagt ctttacctcg ggctcttcat 684721 gctggctgtc actgtgatga atggtgtgat caatcggaag gaaatgcgtg gaaggaaggt 684781 tattcatcca ttttacatat acgttttcat ttcttttaac ctcaatggtc ggtcccggaa 684841 ataagccgtt gtagccccac aggcgggttg gagggagatc gcgatggagc tgatgagtgc 684901 attcctccat ggtgacttcg tagtatgttt tttcttttga ttgctgtact ggctttagtg 684961 tatctgggat tgggagagca tccacaaatt tttcaagtgt cattttcatc tgtccttatc 685021 taaattttcc aaattggtac tatagttaat gacaataagg acgtgatggt tacaaaaaat 685081 cttcgtgctg cagcccgccc gaagaagaaa ataacaaaat cctaaacggc aggccgttta 685141 ggatttgatc agcattaagg caggatatcg ggttgctgct gtgtgactgg gttggcagcc 685201 gctttctcgc tcaccttgcg ttttctgaac acaaggtaag aaatcagaac gattcccgtg 685261 atgacgcctg tcagcagcag ctcgtctctc atggaatcaa taaacgccat ggacactaaa 685321 attccgcaaa tggcgatgat ggtcaagtag gttaggaaag ggaagagcca cattttgatc 685381 ttcaatgctt ctgggtttgt tttttcgagt tttttccgca ttttcagctg ggaaacggcg 685441 atgacaagat agacgagtaa agcgattgcg cctgatgagt tgactaagaa taaaaagacg 685501 gtatccggtg aaaaatagtt cattacgacc gcgatataag agaaaaatgt cccggccaca 685561 atggcttgta cgggaacgcc ttttttgctc aatttcataa aacggcgcgg cgcttcattt 685621 ctttctgcaa gtgaatacag cattctggat gtggtataca aacctgaatt caggcaagag 685681 agtacggctg tgaggacgat aaagttcata atctgtgcgg ctgcgggcac tcctatatgc 685741 tcaagtacag cgacgaaagg gctttctaaa atatttgctg aattccatgg caacagcgcc 685801 acgacaatgg cgattgagcc cacgtaaaag acgatgatgc gccatacaac ggatctggtg 685861 gcttttgtca cagattcgat cgggttggat gtttcccctg ctgcaatggc aacgatttca 685921 gttcccataa aagagaagat gacaacgaca atgccgagca atacggagct gatgccctcc 685981 gggaaaaatc cgcctttgcc tgtaagattc gaaaaaccga ctggctcact gcccggtgca 686041 aagccaaaaa taaaggcaaa accaacgatt agaaaagcaa tgatagtcac aactttaatg 686101 agggagaacc aatattcaaa ctcaccgaaa gacttaacgg agtagacgtt tgtcagggtg 686161 agcacaatgg tcaagatcaa acttgtcagc cacagcggaa tatcatggaa ccagtattga 686221 ataatgccag caccggcaat ggcttcgatc gctatgacga tcacccagaa aaaccagtac 686281 agccagccga ttgtaaatcc tgcccacggt ccgatggcgt cgtgagcgta ttgagaaaac 686341 gatccgctcg tcgggtttac ggcagacatc tcaccgagca ttctcataat aaaaatcacc 686401 aataatccgg ctaacgcgta agaaacaacg gcacccggac cggtcgagtg aatcactgaa 686461 ccgctgccta caaataggcc ggctccgatt acaccggcaa tcgaaatcat tgtcatatgg 686521 cgggtcttta attccttttt taatcctgat tgagactggt tcataagtta cctcctttta 686581 aaatgcaatc attactgaat attatgataa ttgaaactct atcataaata tacagtttgt 686641 cgaaaattcg tgtaagaaaa tataccagct tatttcaaat ttgtagtgtt ttgtttgcgc 686701 tttcagcgaa tgtgtggaaa aaatgtttcg ttttttattc gctgtgtgat tttgcgtaat 686761 atttacaatt cgatagaatg cgagaagcac tggtgtcctt gggtttgatg ggatttttgg 686821 cggagcaaat aaattggatg agagaaaaag tgttccttcg tcactatttt tctgtggcgg 686881 gtgaatcatg tttctgtaga cccactgcgg atcagctttg taagataata ataggaaaat 686941 gtgagcgaga ggaggttttg tatggagaga tatgatgaac tgaaaaaggg agaatccgga 687001 gcgctggtca gcattgccgc gtatctagtt ctttccgcaa ttaaactgat catcggttat 687061 ctttttcact cggaagcact tacggcagac gggttaaata acacaactga cattattgct 687121 tctgttgctg tgctgattgg cctgcgcatc tctcaaaagc ctcctgacga agatcatcca 687181 tacggccact ttcgagcgga aacgattgca tcgcttatcg catcgtttat tatgatggtt 687241 gtcggactgc aagtgctgtt cagcgccgga gaatctattt tttctgctaa acaagagacg 687301 ccagatatga ttgcggcttg gacggcagcg ggcggggcag tcctgatgct gatcgtttac 687361 cggtacaata aaaggctggc caaaaaggtg aagagccagg cgctccttgc tgcggctgct 687421 gataataaat cagacgcatt cgtcagtatc ggcacattta tcggcattgt ggctgctcaa 687481 ttccatcttg cttggattga tacggtcact gcgtttgtga tcggtctgct tatttgcaag 687541 accgcatggg atatctttaa agagtcatct cactctttga cagatggatt cgacataaag 687601 gacatttccg cttataaaca gacaatcgaa aaaatctccg gtgtgagccg tttaaaagac 687661 ataaaagcaa gatacttggg cagtacggtt catgttgatg tggtggttga ggtatcggca 687721 gatttaaata ttacggaaag ccacgatata gccaatgaaa ttgagcggag aatgaaggag 687781 gagcatgcga ttgattattc gcatgttcat atggagcctt tagaacaaaa ataatggagc 687841 ttcctgtcac aggaagcttc agcgtgtcga caaaccctcg cattcgttgt caggtctgcg 687901 cttcggtgct cacgaattag aacattcgct ccgctcctat gctcgtcctt cctagacttc 687961 aagggttttc aatcacgctg aaaagatgac aaaaccctaa aatgaaagcc attttaggat 688021 tttgtcaaca atctggagct tcctgccaca ggaagctttt ttgtgtgttt tggccagctt 688081 tattggtaac aatttgctag aatcgttttt ttatacagat tgctttttgt ggtaaagtta 688141 ggttacatta tgatgaattt tgtagatgac taggaggaaa ataatggcat atcaagaaga 688201 cctgcatcct ttgctgggga aagcagttga acatattaat agagtaatgg ttggaaaacg 688261 agacatcgcc atactcagct tagcagccct tcttgccaaa gggcatgtgc tgcttgagga 688321 tgtacccgga gtcggaaaaa cgatgatggt ccgcgcgctg gcaaagtcaa tcggcgccga 688381 tttcaaaaga atccaattca ctccggattt gctgccatct gatgtaacag gggtatctat 688441 ctataatgcg aaaacgatgg aatttgaata tcgtcccggc ccaattatgg gaaatatcgt 688501 gctggcagat gaaatcaacc gtacctctcc gaagacacag tcggctttgc tcgaagcgat 688561 ggaagagggg agcgtcacgg tagatggcca tacgatgcag cttgccgatc cgttttttgt 688621 gatggcaacg caaaacccgg tcgaatatga agggacctat cctttgccgg aagctcagct 688681 tgaccgtttt ttattcaaac ttcggatggg ttatccgtcc tttaatgaag agcttgacgt 688741 cttatctctt caggaaaaaa gccatccgat tgagacgctt gagccggtta ttgcaaaaga 688801 agacttcatc tttttacaga gggaagtgca aaatgtccgt gctgatgaca gcattaagga 688861 atatatcgtt gaaattgtgc agaaaacgag acagcatcct tctgttcaat taggcgtcag 688921 tccgcgcggc tcaatcgccc tcatgaaagc ggcacaggca tacgcgctgc tgcatcatcg 688981 cgactatgtc ataccggatg atattcaata tttagctcct ttcacgctgc cgcaccggat 689041 gatgcttcat cctgaggcaa aatttgaagg gattcaggca gaagcgatcg taagggagat 689101 catgtcagct gtgaaggtgc cggttcaaag gtcggcggtc cgctgatgaa taagaaatgg 689161 caatggctcg tatatggttg gaagctgatt atattaactt tattgacggc tgctgttttt 689221 tcttatgcga tgtttcaggg cggctttgtc agctggtttt tgttttacgc gtttctccct 689281 tttgtcttgt atgccgggct gttggccttg tatccgctcc gttcttttca ggcttcaagg 689341 caaatggata aaacacaatt gcatgcgggg gacaggctgg gcgtaacggt tacgctgaga 689401 agaaagctgc catttccgct gatgtatatg gtgattgaag attgcctgcc agaaggtatc 689461 gagtcattaa atcgagacgg agccgcggcc aaacggctcg tttttccttg gtttaaacgg 689521 agcatgacga tgtcgtatga attagctcgg gtaccgcgcg gagagcatca ctttcattct 689581 gtcagggtgc gaaccgggga tgttcttggc ttgattgaaa aaacagcatt ttttgagctg 689641 gatgatacct tgtttgttta tccattctat cagcgttttt cctatcaggt gaatgagagg 689701 catcaggaag acggtgtaag cggttcttct cctattcatc agcaccattc ctcagtcgca 689761 gcaagtgtgc ggaattatca gccgggagac cggtttgctg cgttagattg gaagacatct 689821 gcacggcgga gccagctgat gacgaaggaa tttgagcctt ctcgcagcaa aaatctgttt 689881 ctgctgatgg accgtttttc ctcagacgca ttcgaagagg tcgtttcagt gacagcttcg 689941 attcttcatt ctgttttaaa aaacggcgcg ggtgctggtc tggcttccat cgggaaggaa 690001 aaaaacattt tccctattca ggaaggggat cagcatttta agcacatgct tcggcattta 690061 gccatcgctc attgtgatgc ggcagacccg ataagccgat atgcacggga agagctggga 690121 aagccatctg ttcgccaagc tgatcaagtt gttgtcacgg gacagttaac ggaagatatg 690181 ctgcacctcg cagaaatagg aggcggccgg gttacggtga tactggcaaa agagaaagat 690241 gctgagctct ctcaagctga aaatgtcatg attgaacgca tgatgaaacg ccaaatcaga 690301 gttcggatca tgaggggcgg gcgagtttcg cgtgttgttt agaaagagag gtgactggtt 690361 cacatgccgc acgatgatca caagggaagc cgtttgagct tgctgttatt ttattttctg 690421 gcttttttat tgctgtggga gtggcttagg ccgcttgaca gttttactga aacgaaacat 690481 acaggctttt ttagtgtctt tatcggcttg acgtttctgc tgactttttt caggatgagg 690541 tggtttgtca ccgttccttt ttgtgtcata tttacattga tctcgataca catcctgttt 690601 tatcaaggat ctatattcga cttgagctgg gtcagctctt ttttgcagga tgtctatctg 690661 aatatcacgc tgattcaatc agggcaatgg aatgacatga ttccttcatt tcggaccctg 690721 ctgttttttg tgctgctgtg gctgctggtc tatctcctgc attattgggt gatttaccag 690781 agaagaattt tgtttttctt tttgatgaca gtagcgtata ttacgattct tgataccttt 690841 acgccatatg atgccacttt tgccgtaatc cgtatcgtgc tgatcggctt ctttatgctg 690901 ggccttttat acttggaacg cattaagctg atggaaagaa tcacactgcc aaaaacatct 690961 gtcctgaaat ggtttcttcc tttatctgta ttggttttgg ctgcaacggg attcggactc 691021 gccgctccaa aatcagagcc ggcttggcct gatccggtgc cttttcttaa aaaaatcact 691081 catcaagacc gcgtgtctgc aggggaaagc aaaatcggat acgggaatca tgatgaatca 691141 ctcggcggcc cgttccagca ggatgctaca cctgttttta catggcaggg aaaagagcgt 691201 acgtatttcc gtgtggaaac gaaggacacg tataccggaa aaggctggat tgaaacagac 691261 acaggcatgt cgtatcagct tagcaatgga aaagttgaaa atctgtggtt tgaccataag 691321 gttgcgacag agcgccgcac cgtccgtgta aaagtcgata agcactacgg gtataaccat 691381 ctgatgtatc cgattggtgc ggaaaccatt cagccaaagc aggctgtctc acttgaaatg 691441 aacggcaaca cggagcaaat ttctccgatc agtgaacaag ccggtgaaat cagaaatatg 691501 gggaattata cagtaacgta caattccccg gtctataagc tggatgaact gagaaaggta 691561 aaagtgagaa aaaacagtga ggagtacaca ttcagcgatc gctacatgca gcttccagat 691621 tcactgccag agcgggtgag aacccttgcg atcaaactga ctcaggatca cgacaatatg 691681 tttgataagg tgaaagcggt tgaggactat ttagggtcaa atgcgttcac atatgaaaca 691741 gaaaacgtga ccattccgaa gaatgatgaa gattatgtcg atcaatttct ctttgaaacg 691801 aaaatgggtt attgtgataa cttttcttcc gccatggtgg tgctcttgcg ctcggccggc 691861 attccggccc gctgggtaaa gggttatacg tccggcgaat acaaagaagc agggaacaaa 691921 aatggcagca tttacgaagt gacaaataac aatgcccatt cctgggtaga ggtgtatttc 691981 ccggaacagg gctgggttac atttgagccg actaaagggt ttacaaatcc ggctcaattt 692041 acatcttctg acacaaaaga ctctggcagc gatagcagca gctcgccgaa gaaagcaaaa 692101 gagaaacaga aagaagagaa aaaacagccg caaaaagagg aaaaacaaaa ggaaaagcgg 692161 gagccagctg tttctaaaaa gccgtccgct tcgcatacta atgccggtgc gggcttgtat 692221 gcagcgcttg cggttcttgc agtcctcctg gtggcagctg tattgctgta tgttttccgc 692281 tcgttatgga ttcctgtttt cgccgtgagg aaattgaagc ggcgcagtga tcagcacgcg 692341 ttttttgagg catatggcgc gctgctgaaa caactgaaga gaaaaggact gccgaaacga 692401 gacagtgaaa cgctgcgtga ttatgcaaaa cgaattgatg aaaaatacga catagaagac 692461 atgtcaaagc tgacattaag ctatgaaagg gcgctttaca gaaatgaaga ttcttcggcg 692521 ctatggaatg attcgagaga gttatgggaa aatttaatta aaagaagatg gtcttgaccg 692581 cttatcgacg tgttgttaga attagtgaat attatcggag tctgggagcg agttggcctg 692641 actccggcaa acggccttgc caaagagggc ggagcgagct tcatatctgt cctcgttttt 692701 ttctgtgtca aaaaacttag aggagattag gtgacaacca tgacaaagtt agtgaatgaa 692761 atgattcttg tccttgattt cggcagtcag tataaccagc tgattacacg ccgtatccgt 692821 gaattcggtg tttacagcga gctgcatcca catacattga cggctgaaga aattaaaaaa 692881 atgaatccaa aaggaattat tttatccggc ggtccaaaca gtgtgtatga tgaaaactct 692941 ttccgctgtg acgagaaaat cttcgagctt gatattcctg ttttgggaat ttgctacggc 693001 atgcagctga tgactcatta ccttggcggt aaagttgaag cggcaagcca gcgtgaatac 693061 ggaaaagcaa acatccgcat cgaaggcaca cctgatttgt tcagagatct tccgaatgaa 693121 caagtggttt ggatgagcca cggcgatttg gttgtagaag ttcctgaagg cttcactgtt 693181 gacgcgacaa gccatcactg cccgaactca gcaatgagca aagcggacaa aaaatggtat 693241 ggcgttcagt tccacccgga agtgcgccac tctgaatacg gcaatgatct tctgaaaaac 693301 tttgtattcg gtgtttgcga atgcgaaggc gaatggtcaa tggagaactt tatcgaaatc 693361 gaaatgcaaa aaatccgtga aacggtcgga gacaaacagg ttctttgcgc gctaagcggc 693421 ggcgttgatt cctctgttgt tgctgttttg attcataaag cgatcggcga ccagctgact 693481 tgtatctttg tagaccatgg tcttctccgt aaaggcgaag ctgagggtgt tatgaaaaca 693541 ttcagcgaag gctttaacat gaatgtgatt aaagtagacg caaaagatcg attcttaaac 693601 aaactaaaag gcgtttctga tcctgagcaa aaacgcaaaa tcatcggtaa tgaattcatt 693661 tacgtgtttg atgatgaagc ggacaagctc aaaggcatcg actaccttgc acaaggtacg 693721 ctttacacag atatcatcga gagcggtaca gcaacggcgc aaacgatcaa atctcaccac 693781 aatgtcggcg gacttcctga agacatgcag tttgagctga tcgagccgtt aaatacgctc 693841 ttcaaagacg aagtgcgcgc gcttggcaca gagctcggca ttccggatga aatcgtatgg 693901 cgtcagccgt tcccaggacc gggactcgga atccgcgttc ttggcgaagt aacagaagaa 693961 aaacttgaaa tcgttcgtga atcagatgca atcttgcgtg aagaaattgc aaatcacggc 694021 ttagagcgtg atatctggca atacttcact gttcttcctg acatccgcag cgttggtgtt 694081 atgggtgacg caagaacata tgattacaca atcggaatcc gcgccgttac atcaatcgac 694141 ggcatgacat ctgactgggc gcgtatcccg tgggatgtgc ttgaagtcat ttcgacacgt 694201 atcgtaaacg aagtgaagca cattaaccgc gtggtgtatg atattacaag taagccgcct 694261 gcgacgattg agtgggaata agaatcaatt aatggaaacc atctttttgg caattttgcc 694321 gggaagatgg ttttatttgt ttattacgaa caaaatccga ttttgcgcga ctattgttcg 694381 ctttttgtat tgttttttca aaatgaactt ggtacaatag acacagaaat caaataagat 694441 gaattcgtat aatcgcggga atatggctcg caagtctcta ccaagctacc gtaaatggct 694501 tgactacgta aacatttctt tcgtttgata taaataaaac acggttattt attcaaactg 694561 aaatccgtct gtagtcaagc gtcccaaaat gtattgggac gttttttatt tggcgttttc 694621 aggacagaat aaatagcaaa gagtgaaggg agtcaaatag cttgaaaacg ttttttcagt 694681 ttgatgagct gggcaccagc tatcgcaatg aaatcattgg cggattaacg acttttttat 694741 ctatggcata tattttgttc gtcaatccga ttacgcttgc tttggagagc gtgaaagatt 694801 ttccggaggc gctgagaatt gaccagggtg cggtctttac ggcgacagcg ctggcgtctg 694861 cagcaggctg tatcttaatg ggattaatag cgagatatcc gattgccatc gcgccgggta 694921 tggggctgaa cgcgtttttt gcgttttctg ttgtccttgg tatgggtatt tcatggcagg 694981 cagctttgtc cggtgttttt atttcaggtc ttattttcgt tgctctttct ttaacaggtt 695041 ttcgtgaaaa aatcatcaac gccattccgc ctgagctgaa attggcagtc ggtgcgggga 695101 tcggcctgtt tattacattt gttggattac aaggttcagg aatcattaca gcgaatcctt 695161 ctacgctcgt cacgatcgga aacattcaca gcggtcctgt gctgttaacg attttcggtg 695221 tgattgtcac ggttatttta atggtgcttc gcgtgaacgc aggcgtgttt atcgggatgc 695281 tattaacagc ggtagccggc atgattttcg gtttggttcc ggttccgact caaattatcg 695341 gcagtgtgcc aagccttgcg ccgactttcg gacaagcgtg gattcacctc ccggatattt 695401 tctctgtaca aatgctgatc gttattttaa cattcttgtt tgtcggattt tttgatacag 695461 ctggtacact tgttgctgtg gcaacacaag ctggtttaat gaaggaaaac aaattgccgc 695521 gtgcgggccg tgcgctttta gctgattcat cttctattgt gatcggtgcc gtgcttggta 695581 cgtctacaac aacttcttac gtggaatcaa gctcaggtgt cgctgcgggt gcccggtcag 695641 gatttgccgc aattgtaaca gggattctct ttttactggc tacgtttttc tcgccgctcc 695701 tatcagtcgt tacgtcaaat gtaacagcgc cggcgcttat tattgttggt gcattgatgg 695761 tggcgccgct tggcaaaatc gcttgggata agttcgaagt ggccgttcct gctttcctta 695821 ccatgatcat gatgccgtta acgtacagca tcgcgactgg tattgccatc ggatttattt 695881 tctatccgat tacaatggtg tgcaaaggaa aagcaaaaga ggttcatcca atcatgtacg 695941 ggctgtttgt cgtatttatc ctgtacttta tcttcttaaa ataaggaatg aaaaaccagc 696001 tgcactggca gctggttttt ttgttgcaaa agataaaacc atttcatacg atataccgtc 696061 atgtagatgt gccgccatgc tttacttaaa tggaaatgac ttgactgttc aggaaggctt 696121 cggtacctta tataagtgtt ttattttctt gctgaatggt attccgccgt atttttttga 696181 taggagttgc tgacatgacg gaagaaagaa aagaaacgtt tgaagaagaa attaaccaga 696241 gtgaaagaat agatgcagat gaagaaccgc tatcgagaat gtccagaaag gcgagccggc 696301 aaagcaagca gaagcaaaaa caaaagcaga aaccgcgcca ggaacgcggt gaatcaactg 696361 ttaaagacaa gcttgcgtct gtttgggcag ccatcaacag atattgcggt tttgcgttct 696421 cgattttaaa atctccggcg aaaactgtcg taacggatgg tttttctcat tataagtacg 696481 gtctgatttc aatgcttata ttcagtatca ttttttcaat tgggaattgg tttcagttaa 696541 aggcaagctg gaatcggccg ctcggtttcg gagaacgcca tcatgctttc tatgacgggt 696601 ttttagttgt tcttgtgtat ttgctgatct ttttcgcggt aatggtcttt gctatatggg 696661 ctgtctcccg ctatatgatg aagcagaagg tgacgttcag agaagcggct gccgtattgg 696721 gttcattgct tgtacccgta attgctgttt caatcctttg gctgatcttt gcgatcgtaa 696781 atatcccaat gctgacagta ctgtttacgg tgctgatctt gttttccatc ttttttatca 696841 tcgcgctgta tgtacagcgt gtgtaccagg cggcacaaga tgcaccaatt gattatatct 696901 attgtgtatt tgcagtagtt gcgatagcgc tgctgtttac ggcagtgact tggccgttta 696961 tttctgaata tattacggcg tcgttgattc cgctttaatg aaaaaaccgg ctaatcctag 697021 ccggtttttt tatgtcacac tttttacaaa tatatctaaa aaacatagtt gatttgtagg 697081 attaacccgt gtatgatggg gaaaatgctg aaaacgtcca gcgcaaaaac ctttatgttt 697141 aaggaggatg atggacatgg ctgatgtact tcgccgagca attaaccaaa agaagcaatt 697201 tttaaaaacc aaattactgc tctcggaatt ttatcaagga agaggggaac agcttgctga 697261 ctacacgctg agtgagcttg agaaagaata caagtccctt cagaaaatga aaaaagagat 697321 ctgacaatag atataaagag gtgagtctgc tgaaaagcgg gcttttttgt tttgattttg 697381 aaaaggcgag aaagagggta aactactact gttcaacaca taaaagcgtg tcgaaatatt 697441 ttgcttaagc ttacgggcga agctgattgt aaacggctca tttctctagt agaatatgaa 697501 tgctttgtgc aagctgaaga gtagggggat gaataaaatg atgcaaacca tcttatcaaa 697561 tgggatagcc atggttctca taattctcat tattaatatt gtctatgtgt cattttttac 697621 gataagaatg attttaacgc tgaaaggaca gcgttattta gcggccggca tcagtacgat 697681 tgaaatactg gtttatgtga caggactgag tctggtgctc gataacttag accagattca 697741 aaatgtgatc gcgtacgcgc tcggttacgg tcttggcgta attgtcggca tgaaaataga 697801 agaaaaattg gcgcttggct atattatggt caatgtgatt acgaaggagc tcgatcttga 697861 tcttccgaag cagctccgtg aaaaaggcta cggcgtgaca aactgggtgg caggcgggct 697921 tgaaggcgac cgcacagccc ttcagatcct gacgccgaga agatatgaac tccagctata 697981 tgatacgatt aaaacacttg attcaaaagc ctttattatt gcgtacgaac caaaaacaat 698041 ccacggcggc ttctgggtca aagcggtgaa gaagaggaga attaaagaat aatggcaaag 698101 ccgaagaaga aaaagtttga agtgacagag cagcaaacga ttgatgcggt gcttcagcaa 698161 atgaaagaag aaggatatct gcctgtaagg cgaatggaag agcctatttt tatggaaaaa 698221 aaggaaaatg ggtcaattca gatcgttccg tgcgggaaaa aaatcgtatt tgaagggaaa 698281 ttgatctaaa acacgaacat tagtagaatg aatttttgta tcgttcgata atatcgttga 698341 cattatccat gtccgttgtt aagataaaca tgaaatcaaa acacgacctc atataatctt 698401 gggaatatgg cccataagtt tctacccggc aaccgtaaat tgccggacta tgcaggaaag 698461 tgatcgataa aactgacatg gatatatcgc agaagcgaac gactgacgat acatgtacca 698521 tgcccggttt gtattgcttc ctcataagtg caatgcagag cgggtatttt ttattttctg 698581 aaaacaaaag cattagaagg tggggaacag aatgcagccg ctagtaggaa tcatcatggg 698641 aagcacttcc gattgggaga caatgaaaca cgcatgcgac atacttgacg aactcaatgt 698701 tccgtacgaa aaaaaggtcg tttccgctca ccggacgcct gatttcatgt ttgaatatgc 698761 tgaaactgct agagaaagag gcatcaaggt gattattgcc ggtgccggag gagcggcgca 698821 tctgccaggg atgacggctg cgaaaacaac actgccagtc attggagttc cggttcagtc 698881 caaggcgctg aacggaatgg attcacttct ttccatcgtc caaatgcctg gaggcgtgcc 698941 tgttgcgaca acatccatcg gcaaagcggg tgctgtgaac gcaggcctgt tagcggcgca 699001 aattttgtca gcatttgacg aagaccttgc ccgtaagctg gatgagagaa gagaaaatac 699061 aaaacagaca gtgttagaaa gcagtgatca gcttgtctaa acaaatcatc tatccgggag 699121 ctgtaatcgg cattatcggc ggcggccagc ttgggaaaat gatggctgtg tccgccaaac 699181 aaatggggta taaagtcgcg gtcgttgatc cggtgaaaga ttcgccgtgc gggcaggttg 699241 cggatgtcga aattaccgct cattataatg accgtgaagc gattcgaaaa ttggctgaaa 699301 tcagcgatat catcacatat gagtttgaaa acatcgacta tgatgcgctg cattggctaa 699361 aagatcatgc gtatctcccg caaggaagtg agctgctgct tattacccaa aaccgtgaaa 699421 cagagaaaaa agcaattcaa tccgcgggct gtgaagtcgc accgtacagc atcgtcaaaa 699481 caaagaatga attgaaacag gcagtacagg agctcaggct tccggcagtg ctgaaaacat 699541 gccgcggcgg gtacgacggc aaaggccaat ttgtgataaa agaagaggcg caaatggagc 699601 aggcagccgc tctgttagaa cacggaactt gcattcttga aagctgggtt tcttttaaaa 699661 tggaactgtc ggtgatcgtc gttagatcgg taaacggtga aatttcaaca tttccgacag 699721 ctgaaaacat tcaccacaac aatattcttt tccaaagcat cgtgcccgca cgggtagaga 699781 aagggattca gcagaaggct gctgatctcg cagttaagct tgcagatgag cttaaccttg 699841 tcggaccgct tgctgttgag atgttcctga cagaggacgg agagcttttg gtcaatgaac 699901 tggcgccaag accgcacaat tcagggcatt atacgctgga cctttgcgag acgagccagt 699961 ttgagcagca tatcagagcg gtatgcgggc ttccgcttgg gaagacagat ttgctgaagc 700021 cgggcatgat ggtgaatctt ctcggcgatg aagtgaagct tgttgaggaa gacccggagc 700081 ttttaaaaga ggcaaagcta tatatatacg gaaaacatga aatcaaaaaa ggccgcaaaa 700141 tggggcatat tacatttatg aagcagcctg aagacgaatg gattcaggag atcacaaata 700201 aatggatgaa tagagacgga ggacaagcag aatgatcgaa cgttattcaa gacctgaaat 700261 gtccgcgatt tggacggatg aaaacagatt tcaagcatgg ttagaggttg aaattcttgc 700321 ctgtgaagcg tgggcggagc ttggcgtcat tccgaaagaa gatgtaaagg ttatgcgcga 700381 aaacgcgtca tttgacatca accgcatttt agaaatcgaa aaggacacgc gccatgacgt 700441 tgtcgctttt acgcgcgctg tatccgaatc actgggcgaa gaaagaaaat gggtgcatta 700501 cggcttaacg tcaactgacg ttgttgatac ggctctttcc tacttattaa aacaggcaaa 700561 cgatattttg ctcaaggatc ttgagagatt tgttgacatt ataaaagaaa aagcgaaaga 700621 acataaatac acagtcatga tggggcgcac acacggcgta cacgctgagc ctacaacatt 700681 cggcttaaaa cttgcgcttt ggcatgaaga aatgaaacgt aatcttgagc gcttcaaaca 700741 agcgaaagca ggcatcgagg ttggaaagat ttccggtgct gtcggcacat atgcgaacat 700801 tgatccattt gttgaacaat atgtctgtga gaagctcgga ttgaaagcag caccgatttc 700861 cactcaaacc cttcagcgtg accgccatgc tgactatatg gcaacacttg ctttgatcgc 700921 gacaagcatc gagaaattcg ctgtggaaat ccgcggactg caaaagagtg aaacacgtga 700981 agtagaggaa tttttcgcga aagggcaaaa gggttcatct gcaatgccgc ataaacgaaa 701041 tccgattggc tctgaaaaca tgacaggcat ggcgcgcgtg atccgcggct acatgatgac 701101 agcttacgaa aatgttccat tatggcatga gcgcgatatt tctcattctt cagcagaacg 701161 aattattctt ccggatgcga caattgcgct gaactacatg ctgaaccgct tctccaacat 701221 cgtgaagaac ttaacggtct tcccggaaaa catgaagcgc aacatggacc gcactctcgg 701281 ccttatctat tctcagcgtg tgctccttgc tttgattgac acaggcctga ctcgtgaaga 701341 agcctatgat acagttcagc cgaaagcaat ggaagcgtgg gaaaaacaag tgccgttccg 701401 cgagcttgtg gaagcggaag agaaaatcac gtcacgtctt tctccagaaa aaattgctga 701461 ctgctttgat tacaattacc atctgaaaaa tgttgatctg atctttgaac gtttaggttt 701521 agcatagaag aagcttttag cggcttcttc taagccgccg cagtttgaaa attcccaaca 701581 ttcgggttag gaggccttcc gtgaatattg tgaagaatga acttttatac gaaggaaaag 701641 caaaaaagat ctacaaaacc gatgacgaaa acacgctgta tgtcgtgtat aaagactccg 701701 ccactgcctt taacggcgag aaaaaagcag aaatcagcgg aaaagggcgc ttaaataatg 701761 aaatttcaag cctcattttc aaacaccttc atgctaaggg cattaacaat cattttatcg 701821 agcgcatttc ggaaacggag cagctcatta aaaaggtaac gattgtgccg cttgaagtcg 701881 tggtaagaaa tgttgtggca ggaagcatgt ccaaacgtct cggcattcca gaaggcacgg 701941 agcttgagca gccgattatc gagttttact acaaggatga cgcgctgggt gatccgctca 702001 tcacagaaga tcatatttgg cttttgaagg cggcgactcc tgagcaggta gaaaccatta 702061 agtccattac aacaatagta aatgaagagc ttcaaagcat cttcgacgat tgtcatgtca 702121 gattaataga tttcaagctt gaattcggtt tagatgcaga agggcaagtg cttttggcgg 702181 atgaaatatc tcctgacaca tgccgcttgt gggataaaga aacgaacgaa aagctggaca 702241 aagatttatt cagacgcaat ctgggaagct taaccgacgc atacgaagag attttcaata 702301 gactgggagg cattcatcat gtataaagta aaagtttatg tcagcttaaa agaaagtgta 702361 ctagatccac aagggagcgc tgtccagcat gccttgcaca gtatgactta caacgaagtt 702421 caagatgtgc gcatcgggaa atacatggag cttaccattg aaaaatctga ccgtgatctt 702481 gacgtgctag tgaaagaaat gtgcgaaaaa cttcttgcga acacagtgat tgaagattat 702541 agatatgagg ttgaggaggt agtcgcacag tgaaatttgc ggtgattgtg ttacccggct 702601 ccaactgtga tatcgatatg tatcatgctg taaaggatga gctcggccat gaagtggaat 702661 acgtctggca tgaggaaaca agccttgacg gcttcgacgg cgtgttaatt ccgggaggat 702721 tttcttacgg cgattactta agatgcggcg ccatcgcccg atttgcgaat attatgccag 702781 ctgtcaaaca agcagcggct gaaggaaaac ctgttcttgg cgtctgtaac ggattccaga 702841 ttttacagga gcttgggctg ctgccaggcg caatgagacg caacaaagat ctgaagttca 702901 tttgccgtcc ggttgaattg attgttcaga acgacgaaac cttattcaca gcttcctacg 702961 aaaagggaga atcgattaca atcccggttg cccatggtga agggaatttc tactgtgatg 703021 acgagacgct tgctacatta aaggaaaaca atcaaattgc tttcacatac ggctctaata 703081 ttaatggaag tgtcagcgac attgccggtg tcgtgaatga gaaaggcaat gtattaggca 703141 tgatgcctca ccctgagcgc gcggtcgatg aactgcttgg aagcgccgac ggtcttaaat 703201 tgttccagtc tatcgtgaaa aattggaggg aaactcatgt cactactgct tgaaccaagt 703261 aaagaacaaa taaaagaaga gaaactgtat cagcaaatgg gtgtcagtga tgatgagttt 703321 gcattgatag aatccattct tggaagattg ccgaactaca cagaaatcgg aattttttct 703381 gtcatgtggt ctgagcattg cagctataaa aactcaaagc cgattctgcg taaattcccg 703441 acaagcggcg agcgtgtgct gcaggggccg ggggaaggcg ccggaatcgt tgatatcggt 703501 gataaccaag cggttgtgtt caaaattgaa tcacataacc acccatcagc tctcgagcct 703561 taccaaggcg ctgcgactgg cgtaggcgga attatccgtg atgtattctc aatgggtgca 703621 cgcccaatcg ctgtattgaa ctctcttcga tttggtgaac tgacttcacc ccgcgtgaag 703681 tacttgtttg aagaagtagt agcgggtatc gccggatacg gcaactgtat cggcatcccg 703741 acagtcggcg gagaagtgca gtttgacagc agctatgaag gaaatccgct cgtcaacgca 703801 atgtgcgtcg gtttaatcaa ccatgaagac atcaaaaaag gccaggcaaa gggtgtcggc 703861 aacacagtaa tgtacgtagg agcgaaaaca gggcgtgacg gcatccacgg cgctacgttt 703921 gcttctgaag aaatgtcaga ctcgtctgaa gaaaagcgtt ctgctgtcca agtcggcgat 703981 ccgtttatgg agaagctttt gcttgaagca tgtctggaag tcatccaatg cgacgcctta 704041 gtcggcattc aggatatggg agctgccggt ttaacaagct caagtgcaga aatggcaagt 704101 aaagccggtt ctggcattga aatgaatctt gacctgattc ctcagcgcga aacaggcatg 704161 accgcgtatg aaatgatgct ttctgaatca caagaacgga tgcttttggt tattgagcgc 704221 ggacgtgagc aggaaatcat cgatattttt gacaagtatg atcttgaagc ggtttctgtc 704281 ggacatgtga cagatgataa aatgcttcgc ctgacacata aaggagaggt tgtgtgcgag 704341 ctgcctgttg atgccttggc agaagaagca ccggtttacc ataagccttc tcaagagcct 704401 gcttactatc gcgagttttt ggaaacagac gttccggctc cgcaaattga agatgcgaat 704461 gaaatgctga aggcccttct tcagcagccg acgattgcga gtaaagagtg ggtttatgat 704521 cagtatgact acatggtgcg cacgaataca gttgtcgctc ctgggtctga tgctggtgtt 704581 ctcagaatcc gcggaacgaa aaaggcgctg gcgatgacga cagactgtaa cgcgcgttat 704641 ctctatcttg atcctgaagt cggagggaaa attgctgtcg ctgaagcagc gcgcaacatc 704701 atttgctcag gcgcagaacc gcttgcggtg acagataacc ttaacttcgg aaaccctgag 704761 aagccggaaa tcttctggca gatcgaaaaa gcggcagacg gcataagcga agcgtgcaat 704821 gttctcagca ctccggttat cggcggtaac gtatcgcttt ataacgaatc aaacggcacg 704881 gcgatctatc cgacaccagt tatcggcatg gtcggcctaa ttgaagatac agcgcacatt 704941 acaacacagc atttcaaaca agcaggagat ctcgtatacg tgatcggcga aacaaaacca 705001 gagtttgccg gaagcgagct gcaaaaaatg acagaaggcc gtatttacgg caaagcgccg 705061 caaatcgatc ttgatgtaga gctgtctcgt caaaaagcac tgcttgacgc gattaaaaaa 705121 ggcttcgttc aatctgcgca tgatgtgtct gaaggcggct taggcgtagc gattgcggaa 705181 agtgtcatga cgacggaaaa ccttggcgct aatgtgactg tagaagggga agcggcgtta 705241 ttattctctg aatctcaatc tcgcttcgtc gtttcagtga aaaaagaaca tcaagctgcg 705301 tttgaagcaa ctgtcaaaga tgcagttcat attggtgagg taacagctga cggaattctg 705361 gcgattcaaa accaagacgg acaacaaatg attcatgcgc aaacgaaaga gcttgaacgc 705421 gtatggaaag gagctatccc atgcttgctg aaatcaaagg cttaaatgaa gaatgcggcg 705481 tttttgggat ttggggacat gaagaagccc cgcaaatcac gtattacggt ctccacagcc 705541 ttcagcaccg aggacaggag ggtgctggca tcgtagcgac tgacggtgaa aagctgacgg 705601 ctcacaaagg ccaaggtctg atcactgaag tatttcaaaa cggcgaactc agcaaagtaa 705661 agggaaaagg cgctatcggg cacgttcggt acgcaacggc tggaggcggc ggatacgaaa 705721 atgttcagcc gctcctcttc cgttcccaaa acaacggcag cctggcgctt gctcataacg 705781 gaaatcttgt caacgccact cagctgaagc agcagctcga aaatcaaggg agcatctttc 705841 aaacctcttc ggatacagag gttttggctc acctgatcaa aagaagcgga cacttcacgc 705901 tgaaggatca aattaaaaac tcgctttcta tgctgaaagg cgcctacgcg ttcctgatca 705961 tgaccgaaac agaaatgatt gtcgcacttg atccaaacgg gctgagaccg ctatccatcg 706021 gcatgatggg cgacgcttat gtggtcgcat cagaaacatg cgcatttgac gtcgtcggcg 706081 caacgtacct tcgcgaggta gagccgggag aaatgctgat cattaatgat gaaggcatga 706141 aatcagagcg tttttccatg aatatcaatc gttccatttg cagcatggag tacatttatt 706201 tctccagacc agacagcaat attgacggta ttaatgtgca cagtgcccgt aaaaaccttg 706261 ggaaaatgct ggctcaggaa tccgcagttg aagctgacgt cgtaaccggg gttccggatt 706321 ccagtatttc agcggcgatc ggctatgcag aggcaacagg cattccgtat gagcttggct 706381 taatcaaaaa ccgttatgtt ggcagaacgt ttattcagcc gtcccaggct ctgcgtgagc 706441 aaggcgtcag aatgaagctg tctgcggtgc gcggggttgt agaaggcaaa cgcgtcgtga 706501 tggtggatga ctctatcgtg cgaggaacaa ctagccgccg gattgtcacg atgctaagag 706561 aagcgggtgc gacagaggtg catgtgaaaa tcagttcacc gccgatcgct catccgtgct 706621 tttacggcat tgacacttcc acacatgaag aactgatcgc gtcttcgcat tctgttgaag 706681 aaatccgtca ggaaatcgga gccgataccc tctcattttt gagtgtggaa gggctgctga 706741 aaggcatcgg cagaaaatac gatgactcga attgcggaca gtgtctcgct tgctttacag 706801 gaaaatatcc gactgaaatt taccaggata cagtgcttcc tcacgtaaaa gaagcagtat 706861 taaccaaata aaacttgaaa aatgacataa aggcagcgca gttcggctgc ctttctcttt 706921 ctgccctcgt tcggggagat attttgaaaa gcgccttaaa ggagtgaata ggatgtctga 706981 agcatataaa aacgcaggag ttgacatcga agccggatat gaagctgtaa aacgaatgaa 707041 aaaacacgtg gagcgcacga aacggcttgg cgttatgggc agccttggcg gttttggcgg 707101 catgtttgac ctgtctgagc tttcttatca aaaaccagtt ctcatttcgg gaacggacgg 707161 tgtcggcaca aaattaaagc tcgctttttc catggataag catgacacga ttggcgtgga 707221 tgctgttgca atgtgtgtca atgacgtgct ggcacaaggt gcagagccgc tgtttttcct 707281 cgattattta gcggttggca aagcggaccc agtgaaaatt gaacagattg tacaaggtgt 707341 tgcggaaggc tgtgagcagt caggttcagc cttagtcggc ggtgaaacgg ctgaaatgcc 707401 ggggctctat acagctgatg aatacgatat tgccggtttc tcagtcggag tggcagaaaa 707461 ggacgaaatc gtgactggag aaaaaattga agagggccat ctgttgatcg gcctcagctc 707521 cagcggcctt cacagcaacg gcttttccct tgtcagaaaa gtgcttctgg atgatgcgga 707581 gctggacctc gatacaacat atgagccgtt tgaacgcccg cttggcgagg aattgcttga 707641 accgacaagg atttacgtga agcctgtgct tgccgcggtc aaaagcggaa aaatcgacgg 707701 catggcgcac gtgacaggcg gaggatttat tgaaaatatt ccgcgtatgc ttccggaagg 707761 cttaagtgcg gaaattgatc atggctcatg gccgatcccg ccgatttttt ctttcttgca 707821 agagtacggc aagctaaagg aagaagacat gttcaacgtc tttaatatgg gtatcggttt 707881 tgttttggca gtcaaagaag agcatctgac agatgtgatc ggaacgcttg aaagccatgg 707941 cgaaaaagcc tatttaatcg ggcgtgtgaa aaaaggtgaa ggcgtcacat tcggcggtgc 708001 ggcactttca tgaaaaagtt tgcggtattt gcatcaggaa acggttcaaa cttcgaagcc 708061 atcgtcacgc gtttgaagga ggagaactgg gatgcgtcag cagcgctcct cgtttgcgac 708121 aaaccgcagg cgaaagtcat cgaacgggcg gaagcattcc acattccatc cttcgcattt 708181 gagccgaagt cttatgaaaa caaggctgca tttgaacaag ccatcattga acagcttcgt 708241 cttcacgagg ttgaattgat tgctcttgcc ggctatatga ggctgatcgg tgatacgctc 708301 cttcaagcat atgggggaaa aatcattaac attcacccat cgcttcttcc ggcgtttcct 708361 ggaatcgacg cagtcggaca ggcgttccgg gcgggtgtga aggtggccgg aatcaccgtg 708421 cattatgtcg atgaaggaat ggatacaggt ccgatcatcg ctcaaaaggc aatcgaaatt 708481 gatgaacatg atacattgga aacaatcgaa cagcgaattc acaagcttga gcataaatgg 708541 tatccgagtg tgattaaaca gctattagga ttaaataaca gaggtgaaaa ggcatgacca 708601 ttaaacgtgc attaatcagt gtttcagata aaacaaatct cgttcctttc gtaaaagaac 708661 tgacagagct tggcgttgaa gtcatctcca caggcggaac gaaaaagctt cttcaagaaa 708721 acggtgtgga tgtgatcgga atttctgaag tgacaggctt tcctgaaatt atggacggcc 708781 ggttaaaaac cctacacccg aatattcacg gcggccttct ggcggttcgc ggcaatgaag 708841 agcatatggc gcagatcaat gaacacggga ttcagccgat tgacctcgtt gtcgtcaacc 708901 tctatccatt taaagaaacg atttctaaag aagacgtcac gtatgaagaa gcgatcgaaa 708961 atatcgacat cggcggacct ggcatgctgc gcgcggcatc aaagaaccat caggatgtca 709021 cggttatcgt cgatccggcc gattacagcc cagtgctaaa tcaaatcaaa gaagaaggca 709081 gcgtatctct tcagaaaaaa cgcgagctcg cggcaaaagt attccgtcat actgcggcat 709141 atgatgcact gatcgctgac tatctgacaa atgttgtcgg tgaaaaagaa ccagagcaat 709201 tcactgtgac atttgagaaa aaacaatcgc ttcgctatgg agaaaacccg catcaggaag 709261 caactttcta tcaaacagct cttcctgtca aaggctccat tgcgcaagca gaacagcttc 709321 acggaaaaga gctttcttac aacaacatta aagacgcgga tgctgcagtt caaatcgttc 709381 gtgaattcac tgaaccggct gctgttgctg tgaagcatat gaacccgtgc ggcgtgggaa 709441 caggaaaaac gatcgcagaa gcgtttgaca gagcgtttga agcggataaa acatctatct 709501 tcggcggcat tatcgcgctg aaccgtgaag tggacaaggc aactgccgaa gcgcttcaca 709561 acattttctt agaaatcatc attgcgcctt cattcagcca agaagcgctc gacgtcctga 709621 ctgcgaagaa aaatctccgt ctgctgacgc ttgacgtatc cgccgctgtt caaaaggaaa 709681 aacagctgac atccgttcaa ggcgggctgc tgattcaaga tttagatatg cacggcttcg 709741 atgatgctga gattagcatt ccgacaaaaa gagagccgaa cgagcaagag tgggaagact 709801 tgaagcttgc ttggaaagtc gtgaagcatg tgaaatcaaa tgcgattgtt ctcgcgaagg 709861 acaacatgac agtcggcgtg ggagcaggcc aaatgaaccg cgtcggatcg gcaaaaatcg 709921 caatcgagca agcaggggaa aaagcgaagg gcagcgcgct cggttcggat gcatatttcc 709981 caatgccaga tactgtcgaa gaagcggcaa aagcgggcgt tacagccatc attcagccag 710041 gcggatcgat ccgagatgag gattccatca aaaaagcgga tgaatacggc attgccatgg 710101 tattcaccgg catcagacac ttcaaacatt aaggggatga aaacgacgtg aatgtattaa 710161 ttatcggtaa aggcggaaga gaacatacgc tggcgtggaa ggcagcgcaa agcagcctcg 710221 tcgagaatgt atttgccgct cccggaaatg acggcatggc agcttccgct cagcttgtaa 710281 acattgagga aagcgaccac gcagggcttg tctcatttgc aaaacaaaat caggtcggcc 710341 tgaccattgt cggccctgag gttcctttaa ttgaaggtct ggtggatgaa ttcgaaaaag 710401 cgggcttaca tgtgttcggt ccgtcaaaag ctgcggcgat catcgaagga agcaaacagt 710461 tcgctaagga tttaatgaag aaatacgaca ttccgaccgc agaatacgag acgtttacat 710521 cctttgatga ggcgaaggca tatgtgcagg aaaaaggtgc tccgattgtg ataaaagcag 710581 atggacttgc agctggaaaa ggcgttactg tggctatgac agaggaagaa gcaattgcgt 710641 gcttgcatga ctttcttgaa gatgaaaagt tcggtgatgc gagcgcgtcc gttgtcattg 710701 aagaatatct ttctggtgaa gaattttctc taatggcctt tgtcaaaggg gaaaaggtgt 710761 atccgatggt gattgcccag gatcacaagc gggcgtttga cggagacaaa ggcccgaata 710821 caggcggcat gggcgcctac tcgccagttc cgcaaatttc ggaagaaacg gtccgccatg 710881 ctgtagaaac gatcgttaag ccggctgcaa aagcaatggt acaagaaggc cgttccttca 710941 ctggcgtttt gtacgctgga ttgatgctta ctgaaaacgg ctcgaaggtc attgaattta 711001 atgcccgttt cggcgatccg gaaacacagg tcgtgcttcc gcgcatggaa tctgatctgg 711061 tacaggtgct tcttgatctt ttagatgata aggaagttga cttaagatgg aaggataccg 711121 cggcagtgag tgttgtgctt gcatcagaag ggtatccgga aagctatgca aaaggcacgc 711181 cgatcggcag ccttgcagca gaaactgagc aggtcgtggt cttccatgcc ggaacgaaag 711241 cagaaggtgg agagttcgtt acaaacgggg ggcgcgtcgc caatgtgacg gcttttgatg 711301 aaacgtttga agcggctaga gaccgagtgt acaaagcggt tgatgaaatt ttcaaaccgg 711361 gactcttttt cagaaaagac attggggcac gcgctttaaa ggctgcccaa aaataagtga 711421 ggaaaacccg cagaatagct gcgggttttt tgttatcaaa aagcgggatg gcagctagaa 711481 gaagaaagca caacgagcgt ggttggtttt ccatgggcca tcgaggtgtc aataaaatcc 711541 tcaagcgtat gtaccgattc agtcacgacc tttgtcacat agctgtacat ccccgtgatg 711601 cggtggtttt ctgctacatc aggatgcgat gttgcaaagg cggcgtagtg cttgcagctt 711661 ttcggctcca tgagaataaa agcggtgaca tgcttgttta gtttttcgta acagatattc 711721 gcgctgtagc cggtaatcac tcctttgtct tccagcttcc tgacacgctc cgccgcgctt 711781 ggcgagctga gtccgacaag ctttcccagc tcaaccatcg ttaatctgcc gtttcgctgc 711841 aaatgcgaga gaatctgaag gtctgtatcg tccatttgtc tggctccttt acatatttag 711901 gcgaatgaat gaaaattcct ttgatcgtaa ggtaatgctg ttgatttaac ttcattgtag 711961 catatggatg ccgtcttatt ttttctataa taaagccatc aatcagagag ggggcatcat 712021 gttgccagaa ttgcagcgct ctattacttg gatacaaggg acggcgttaa cgattggggc 712081 ggttttagga tgcgggatat taatcctgcc gtctgtcacc gcggacacgg ccggccccgc 712141 ttctttattt gtttgggtgt tcatgtcctt cttatccttt tttcttgtcg gcacgctggc 712201 ccggcttgtg aaaatagcgc ctagcgcggg aggaatcacg gcttatgtgc agctggcctt 712261 tcagaaaaaa gccggggcta ttttgggctg gatcatgtta gggtccgttc cgatcggcgt 712321 tcccatcatc gctttgactg gcgcgcatta cgtcagttac atcacagagg cggccgattg 712381 gcagattaca ttgattgctg gttgcatgct ggctatatct attttgcttc atatgagagg 712441 gattcaacta tcagcaaaca ttagtacact cgttatatgt gtcatcgtat ttctgcttgt 712501 cacttctatt gctgtgtcat tgccacacgt cacgatagca gaattcaagc cgtttcttcc 712561 gcatggctgg tctgccgctg gatctgtttc tgttatgatt tttttctctt ttgtaggctg 712621 ggaaatgatt accccgttgg ctgaggaatt tcatcgtcct gaaaaagatg tcccgctcag 712681 cttgtttttg gcagcgtctt gtgtggcggg gctgtatatc atgctgtcat ttgtgaccgt 712741 gggtactcat tcatatggag agaatggaga aattgcatcg cttgccatgc tcatttcaaa 712801 aggagcagga gaaagcggtg tatatgtcac ggtatgttta gcgctgttta ttacattcgc 712861 caccatccat gccaatattg ccggtttttc aagaatggtg tacgcattgg cgagagaggg 712921 gcacataccc gtattttttg gaaaactcag tgcgacaaaa cgtacgccta ttcgcgtttt 712981 gacagcgatg gccgcagtgt ttggcttagt gcttgcagcg catggtctgt ttcaaatcga 713041 tttgacgact ctgttgaaag ggccgagcgc ggcttttatc gcatcttaca tatgtacaat 713101 ggcggcagca ctgaaactgc tgggcaggag agatataggc tggtggatgg cgctcggggc 713161 atttgtggcg tgcgcggtga tttattcatt cagcggctgg gcactgcttt atccggcagt 713221 gctggcagct gcaggatatt tctatatgaa aacaaagggt gggcataaaa aaaagcttga 713281 tcacgttttg tgatcaagct tttccattta tccgttttga tgctcgttat ttccagaatc 713341 gctgtgttga aacatgtagg tcacaggaca gaagcgcaag attcccgaac ccgctttcat 713401 ggcccccata aagatgtaaa agagatgcat tctgcaccaa ggttttttcg taaactttgc 713461 actggcggct gacataatcg tcaatccgca ggcgattctg aacacggcat tgatgagact 713521 gatgtttggc ttcaaggaaa tccgctcctt ttacttaaaa aagtttttta atcgaacctt 713581 caaaaatttg taacgttttt atcgtgcgtg atgaggaagg atgtgatacc atgagtctaa 713641 tacatgtaaa ggagagtatg tgaatgtccg aacgcacctt taactggaaa aacaaagaca 713701 tcagggcaca ggttgatgtt gtagactcaa agctgcttcc aacgctcctt ttacggaatg 713761 ctctcgtctt aaatccatat gtaaaacaat ggctgaaaaa aaacatttgg atttatcagg 713821 accgcattgt ttatgtgggt catgaacttc cgaatagagc cgaagaaatt catacgattg 713881 attgtgaagg aaaatacatt gtgccaggtt atattgaacc gcacgcacat ccttttcaaa 713941 tatataatcc ccaaacactg gcggaatatg tgtctcaata cggaacaacg acattcgtga 714001 atgataactt atttttgctt ttgcaaagcg gaaaaaagaa agcgcttacg attttgaatg 714061 aactcaaaaa gcagcctgtc cagtattttt ggtggtcacg ctatgacctc cagaccgagg 714121 ttctgaacga ggaccacgtc cttccatttg acgtcagaaa acagtggatt gaacatccgg 714181 atgtgattca aggcggagaa atgaccggat ggcctcgcct ggtagatggt gatgatttaa 714241 tgctccactg tatgcaagct acaaagaaac agagaaaacg tattgaaggg cattttcccg 714301 gcgcttctga taaaacgctt acaaaaatga agctgttcgg tgcggattgt gatcatgaag 714361 cgatgacagg tgatgaagtg atgagaaggc tggaactggg ctattatgtt tcccttcgga 714421 actcttccat tcgccccgat gtaagaaaaa tcttgcaaga gctgcatgag aagggcttcc 714481 gctattatga ccacttcttt tacacgacag atggcgcaac cccgaatttc tataaaggcg 714541 gcatgacaaa cgagctgatt cgcattgcgt tagaagaagg cgtacctgca atcgacgcct 714601 acaatatggc atcatttaat atcgcaaagt attaccaaat ggatgattat ttaggagttg 714661 tcggaccggg cagactggca tcgctaaaca tactggaaga tccgttaaat ccgaatccag 714721 tgactgttct gtcaaaaggg accattctgc gtgaaaacgg ctgtgatttg aaggcgttta 714781 caaagacgga ctggcacaaa ggcggtcttg tcccgcttga gctttcatat gatatgacga 714841 tggatgactt gcagttttct atgccgatgg gcgtgaaaat gcggaatgcg gttattatgg 714901 agccatatat gattgagatc gacaattcga tggaacagct ctcgtttgac catgatgaaa 714961 gttatttgac gatgctcgac agacacggga aatggcgcgt caatacgatg ataaaagggt 715021 ttgcctcaag cgtgcaggga tttgtaagct cctttacgac gacgggcgac attgtcgcga 715081 ttggaaaaaa taaagcggat atgctgctcg ctttcgcccg catgaaagaa atcggaggag 715141 gaattgtttt agcggagaac ggaaacattc tgcatgaaat cccgcttgcg ctgtgcggct 715201 gcgcctcttc ggaagcgtat gaagacgtgc ttgagaagga acaaaagctg agagatcttt 715261 tgactgaaag aggctatgag ttttgcgatc ctatctatac gctgctcttt ttgcaaagta 715321 cgcaccttcc gtatatacgc attacgccaa gaggaatatt cgacgtcatg aaaaaaactg 715381 tactctttcc atcgataatg cgttaaaata taaaagagca gggagccgac atatgaaaaa 715441 atggatgaca gtttgcgcgc tgtgtttcgt gttttttctg ctggtatcct gccagcagaa 715501 ggatgctgtc ccggatactg caaagaagct gaaagctcct ttaacggggc taaagactga 715561 acagaaagtg actgaacgcc gccctgttgc tgttgtggtg aacaatcacc cgaaggcgag 715621 gccgcagtcg ggtctgtcta aagccgacat tgtcatagaa gcgctagccg aagggcaaat 715681 cacaagattt ctggccattt tccaaagcca gatgcctgaa actgtcggac ctgtgcggag 715741 cgcgcgggaa tatttcgtca ctctcagcaa tggctttgac agcatatttg tccatcacgg 715801 ctggagtccc ggcgccaaaa agcagctgga atccggagct gccgattata tgaacggatt 715861 ggattttgac ggaagcttat tttggagagc tgatttcagc aaaccgcccc acaattccta 715921 tacgtcttat gattacataa aaaaggcggc agaacaaaag ggttataagc tgaagcagga 715981 aacaaatccg ctgctgtttc aaacatcaga tgcaaaacct gcaaatgaat cttacaatgt 716041 tcgggtagat tatggaacaa ataacgttac aaatcttgtc gaatacaact atgataaaaa 716101 agctgaattt tatacaagaa gctctgatgg tgtcataacg acagaccggg aaaccggaaa 716161 gccggttgca atgcaaaata ttttcattgt tgaagccagc catcatatta ttgatcaaga 716221 tggaaggcgg gacatcgact tggaatcagg aggaaaaggt ctgttgtttc agcacggaaa 716281 cgtcattgaa acagactgga aacaagtgaa tggcagaatt gtgccggtaa aagacggcaa 716341 gtggcttccg tttgtgccag gaaagacttg gatcaatatc gtacctgatc ttgatgcggc 716401 ttccattagt aaaggagaag gtgtgtaacg atgcaaatcg ataaattacg cggcaaagag 716461 ctggaccagt tatttaactc gatcttatcg ctgaaagacc tggaggaatg ttaccgattc 716521 ttcgatgatc tatgcacaat taacgaaatt caatcgctgg ctcagcgcct tgaagtggcg 716581 cgcatgcttc gcgaaggaaa cacgtatcat aagattgaaa cagaaacagg cgcttccacg 716641 gctacgattt cccgtgtgaa acgctgctta aattacggaa atgacgctta tgaaatggcg 716701 cttgaccgtg tgaaggagac ggaaacagag tcttcttcca aataaaaaac cgccctgccg 716761 tctggcaagg gcggtttctt tatgaaacaa attgatggat caggttgtcg atattgatga 716821 tactgccatc ctctttccga tagacaacat gctccttgga aaaatgaatc ggcgaattaa 716881 tccctgctgc ggctgcaagg ttaaatagtc cctcgcgcaa tgaaataacg tagttgcaga 716941 cacgatgctg tttttcctca acgctcagtg ctttttgcaa tttcggatct gtcgtcgcca 717001 cacctgccgg acaggtgttg gtgtggcaga cgagagcgcg gatgcagcca acggaaaaca 717061 tcatgccgcg tgcgatgtta acaaagtcag cgccgagggc taaggcgacc gcgattttat 717121 caggagtcag gagctttccg gaagcaaaga ttttcagctg gctgcgcaag ccgtactgtt 717181 taagaagcgt gtccacaata ggcagcgctg tcataatcgg aaggccgact gtatccgcga 717241 gctcgtaaaa ggaagctccg gtaccgcctt cacttccgtc gatcgtgata aaatccggat 717301 gctttccgct tttctgcata tgagagaaaa gctcatgcaa ttcttcagga tgccctgcga 717361 ccagtttgat gccgactggc ttttgtccga catctctaag tttttcaata aagtcgagca 717421 tttcaggagg gtttgagaat tcataaaagc ggttcgggct gtcaatcgac tttccaggtt 717481 cgacattccg aatgtctgcc acttcctctg atactttggc gccgtccaca tggccgccgc 717541 gggttttcgc tccttgtgcc agctttagct caaacgcttt aatctggtca atcctgcttt 717601 ttcttttaaa ttcctcccac gaaaattccc cgtttctttt gcgcacgccg aataggcccg 717661 gtccgatttg gcaaatgata tcggcgccgc cctttaagtg atattcagac aatccccctt 717721 cacctgtatt catccaggtg ccgcctgcca gatggagccc ttttgagagc gccgtaacag 717781 cccgttctcc aagagaaccg tagctcatgg cagactggcc gactaagccc ttcacataaa 717841 atggcttctc gcatgtatgc tcgccaatca cctgtacatc atcaggatgg agaaaatacg 717901 ggtctgcctt gatatgttcg gcatgctcct tgcgtttgaa cagattgtca gcatccattt 717961 tatagatttg ggtttcaatt tttggcgttt gatttacatg catttcttcc ctttgttttg 718021 gaaacatagc gttacggata taatagccag gtttatcaaa atctcttaca gatccaaagc 718081 ccatcattct gcttttgtat ttgccggaga tgacggtttg ctcatattcc tttcgtgaaa 718141 atggctgctc ttcattgtca ttgctgtata aatactgtct gagctccggc ccgatttttt 718201 caaggatata ccgaaacctt ccgatgacgg gatagttgcg aagaattgag tgctcctgct 718261 gtttttcatc ctttatgtag atccaggcaa acaagacgat cgggatagcg atgatcccaa 718321 tgataaatgc gatgagtgct attatgatgg tttccatctc tcagcctccc tttttatgta 718381 accatttcca cagtagaaca ctttccaaac aatagcagaa ggaatctggt gaaaaatgtg 718441 tgctcctgcc gatacaggac tcaccatgca ggtactgcca tatgctctct ttttttatga 718501 aaaaagaatc aaaacacctt tttcagtgaa taacgagatt aacggctttt tccgtttttc 718561 cgcgctatgt gaatttgtta taatgtttaa atggtaacaa acgaatggag gaacgtatga 718621 cgtgtacgat gtaacggagt ggaagcatgt ctttaaactc gatccaaata aagatttgcc 718681 tgacgaacag ctggagattc tttgcgaatc aggaacggat gcggtcatta tcggaggaag 718741 cgatggtgtg acagaggata atgtcctgcg gatgatgtct aaggtaagac ggtttttggt 718801 gccgtgtgtc ctagaggtat cagcgattga agcgattgtt cccggctttg acttatattt 718861 tattccgagt gtattaaaca gcaaaaacgc ggattggatt gtcggaatgc accagaaagc 718921 catgaaggaa tacggagaac tgatgtctat ggaagaaatc gtggcggagg gctactgcat 718981 cgcaaatcca gattgcaaag ccgcggcact gactgaagcg gacgccgatc tgaatatgga 719041 tgatattgtc gcctatgcgc gtgtgtcgga gctgctgcaa ctgccgattt tttatttaga 719101 atacagcggc gtgcttggag acatagaagc tgtcaagaaa acgaaggctg tattggaaac 719161 gtccaccttg ttttacggcg gcggcatcaa ggatgcggaa acggccaagc agtacgcaga 719221 gcatgcggac gtgatcgttg taggcaatgc ggtgtatgaa gattttgaca gggctttgaa 719281 aacagtagcg gctgtgaaag gcgagtagta aattgtacgg atttggttta tgatagaacg 719341 tatgttttgt ataggcgggt gaacaaattt tgaattatat tagcaatcaa ttactaagcg 719401 gtttaaaccc cgttcagcag gaagcagtca aaacaacgga cgggcctctt ttgctgatgg 719461 cgggagcggg tagcggaaag acgcgtgtcc tgacccatag aattgcttat ttaatggcag 719521 aaaagcatgt ggcgccgtgg aacattctgg cgatcacatt tacaaataaa gcggcacgcg 719581 aaatgaaaga acgtgtggaa agcatcctcg gacccggcgc ggacgatatc tggatctcca 719641 cattccacag catgtgcgtg cggatcttgc gcagagatat cgaccggatt gggatcaacc 719701 gaaatttctc catccttgat acggctgacc agctttcagt gatcaagggg attttgaagg 719761 agcgcaatct tgatccgaag aagtttgacc cgagaagcat cctcggcacg atcagcagtg 719821 caaaaaacga attgaccgaa ccggaggaat tctctaaagt tgctggcggc tactacgatc 719881 aggtggtcag cgatgtatat gctgattatc agaagaagct attgaaaaac cagtcgctcg 719941 atttcgacga tttaattatg acgacgatta aactgtttga cagagtgcct gaagtgcttg 720001 aattttatca gcgcaaattc cagtacatcc acgttgatga gtatcaggat acgaacaggg 720061 cacaatacat gctcgttaag cagcttgccg agcgtttcca gaacctttgc gttgtggggg 720121 attctgatca gtcaatctac agatggcgcg gcgcggatat caccaacatt ctttcatttg 720181 aaaaagatta tccgaatgca agcgtgattt tgctagaaca aaactatcgt tcaacgaaac 720241 ggattttgcg cgcggctaac gaggtcatta aaaacaactc taaccgcaaa ccgaaaaatt 720301 tgtggacgga aaatgatgaa ggcatcaaga tttcctatta tcgcggtgat aatgagttcg 720361 gtgaaggaca gtttgtggcc ggcaaaattc atcagcttca cagcacaggc aagcggaagc 720421 tgtcggatat cgccatatta taccggacaa acgcgcagtc ccgtgtgatt gaggaaacgc 720481 ttctcaaagc gggcttgaac tataacattg tcggcggcac aaagttctat gacagaaaag 720541 aaattaaaga cattcttgcg tacctgcgcc tcgtatccaa tccggatgac gatatcagtt 720601 tcacgcgcat tgtcaatgtg ccgaagcgcg gagtcggcgc gacatcactt gaaaaaatcg 720661 cttcgtatgc ggccataaac ggcttgtcct ttttccaagc gattcagcag gttgatttta 720721 tcggcgtcag tgccaaagcg gcaaacgcgc ttgacagctt tagacagatg attgaaaacc 720781 tgaccaatat gcaggattac ttatccatta cagagctgac agaagaaatt cttgataaga 720841 cggaatacag agaaatgctg aaggctgaga aatcgatcga agcccaaagc cgtttagaaa 720901 atatcgacga gttcctgtct gttacgaaaa actttgaaca gaaaagtgaa gacaagacac 720961 tcgttgcgtt cctgacagac ttggcattga tcgcagatat tgatcagctc gatcagaagg 721021 aggaagagtc aggcggcaag gatgcgatca ccctgatgac actgcacgcc gcgaaaggac 721081 tggagtttcc ggttgttttc ttgatggggc ttgaagaagg cgtcttcccg catagccgtt 721141 cactcatgga ggaagcggaa atggaagaag aacgccgcct tgcgtacgtt gggattacaa 721201 gggcggaaca ggagctttat ctgaccaatg ctaaaatgcg caccttgttt ggccggacaa 721261 atatgaaccc ggaatctcgc ttcattgctg aaataccgga tgatttattg gaaaacctaa 721321 atgagaaaaa agaaacaaga gcgacgtctg cgagaaaaat gcagccgaga cgcggccctg 721381 tttcacgccc ggtatcctac gccagcaaaa caggcggcga caccttgaac tgggcagtcg 721441 gagataaggc gggccataaa aaatggggaa caggaactgt cgtcagcgtg aaaggcgaag 721501 gagaagggac agagcttgat attgccttcc cgagccctgt cggcgtgaaa cgcctgttag 721561 cagcatttgc tcctattgaa aagcagtaat tgaagaggaa aggaagaagc agatggacaa 721621 agaaacagcg aagcagcggg cagaagaact gcgccgcacc atcaacaagt atagctatga 721681 atattacacc ttagatgaac cgagcgtccc agatgccgaa tacgacagat tgatgcagga 721741 gctgatcgcg atcgaggagg agcacccaga cctcagaacg cctgactctc ctacgcagcg 721801 cgtcggcgga gccgtgcttg aagcgtttca gaaagtcacc cacggcacac cgatgctcag 721861 tctgggcaac gcctttaatg ctgatgatct tcgtgatttc gaccgccgtg tgcgccagtc 721921 cgtcggcgac gatgtggcgt ataatgtgga gctgaaaata gacggtcttg ctgtttctct 721981 ccgttatgaa gacggctatt ttgtcagagg ggccacaaga ggtgacggga cgacgggaga 722041 ggatatcacg gagaatctga agacgatccg caatatcccc cttaaaatga accgtgagct 722101 gtcgatcgaa gtgcgcggcg aggcgtatat gccgaagcgt tcgtttgaag cactcaatga 722161 ggaacggatt aaaaatgagg aagaaccgtt cgccaatccg cgaaatgccg cggcgggatc 722221 tctcagacag ctcgatccga aaattgcagc gaaacgaaac ctcgatatct tcgtctacag 722281 tatagcggag cttgacgaga tgggtgtaga gacgcaaagc caagggcttg attttctcga 722341 cgaactcgga tttaaaacga atcaggaacg aaaaaaatgc ggcagcatag aagaagtcat 722401 tacgctgatc gatgagcttc aggcgaagcg cgcggacctg ccgtacgaaa tagacggcat 722461 tgtcattaaa gtcgattctc tcgatcaaca ggaggagctc ggttttacgg cgaaaagccc 722521 gcgctgggcc atcgcgtata agtttcctgc tgaagaggtc gtgacgaagc ttctcgatat 722581 cgaattaaat gtcggcagaa cgggtgtgat tacgccgact gcgattcttg agccggtaaa 722641 agttgccggc acaacggtct caagagcatc ccttcataac gaagatttaa ttaaagagaa 722701 ggacattcgg attttggata aggttgtcgt caaaaaagcg ggcgatatca tcccggaagt 722761 tgtgaatgtc ctcgttgacc agcgcacagg agaagaaaag gaattcagca tgccgacgga 722821 atgtcctgaa tgcggcagtg aactcgtccg gatcgaagga gaagtggcgc ttcgctgcat 722881 taaccctgaa tgtccggcgc aaatccggga agggcttatc catttcgttt cccggaatgc 722941 catgaacatt gatgggctcg gcgaacgagt gatcacacag ctgtttgagg aaaaccttgt 723001 ccgcaatgtg gcagatttat ataagctgac gaaggaacga gtcatccagc tcgagcgcat 723061 gggcgaaaag tccactgaaa acctgatcag ctccatccaa aaatcaaaag aaaattcgtt 723121 agagcgcctg ctgtttgggc ttggcatccg ttttatcgga tcaaaggccg caaagacgct 723181 tgccatgcat tttgaaagct tggagaacct gaaaaaagcc tctaaagagg aacttctcgc 723241 ggtagatgaa atcggtgaaa aaatggctga tgctgtgatc acctattttc ataaagaaga 723301 aatgcttgaa ctcttgaatg aacttcagga gctgggcgta aacacgctct acaaaggccc 723361 gaaaaaagta aaagcagagg acagcgactc ttactttgct ggtaaaacaa ttgttctgac 723421 aggaaagctg gaagagctgt caagaaacga agccaaagcg caaatcgaag cgctgggcgg 723481 aaagctgact ggaagcgtca gcaaaaacac agacttagtc atcgccggag aagcggcggg 723541 aagcaagctg acaaaagcac aagagctgaa cattgaagtg tggaatgaag aacagttaat 723601 gggagagcta aagaaataag aggagtgttt tctattgaaa aagacgttgg cattggcggc 723661 aacggcggca gtattaatgc tgtctgcctg ctcgtcaggt ttcggggggg agaaggagga 723721 agagattacg caaaagacgg cgaaatcgtc agaaaaagcg attgtcccga aatataatat 723781 ctctgactcc tattacaaaa tggtgctgcc gtttaaggca ggcaaagcgc gcggcttaac 723841 aacggaacag ctgaatacaa ggctggacat tgacgaattt gaaacagggc tgatgcgcct 723901 tgcccaagat tctttctcaa ctgacgatta tctgttccaa gaaggacaat atttagatga 723961 ggatacagta ttaagctggc tggcacggaa aaaaacgggc tctgatttga aaaaagccga 724021 aaaagaagat aagaacttca aaaatgaagg cttgaacccg gcgctcccga gttctggttc 724081 aacagaagaa aagaacgaaa gcagcccaat ttatttagca tccatgcttg agcacgatta 724141 tttagtcaga aaagacaaga attctatcca gcttggcggc gtcatgatcg gactggcgtt 724201 aaactcagtg tattactatc gtgaaaaaac tggcgacccg caaaaagaag tggagattaa 724261 agacagcacg cttcgccagc agggagaaaa aattgcacag gaggttatta accgcctccg 724321 caaaaaagat aacttgaaga atgtgccgat taccgtggcg ctctacaagc aggcgtcaaa 724381 aacatcgatt gtgccgggga acttcatcgc caaaacagag gtcaaagcag gctctactga 724441 tatctcaaat tgggatgaca tcaatgaaaa atatgtattc tatccggcgg atacaaccac 724501 agcagaaaag tacccggatg acaccgaggt ctttaagcgg ttcaaaaact caattgaaga 724561 atatttcccg aactatacag gcgttgtcgg tacagcgctg tatgaaaatg atgaaatgaa 724621 gaaaatgaag attgacatac caatgcaatt ctacggaaaa agtgaagttg tcgcgtttac 724681 ccagttctta acgggtgaag tgatggacta ctactctaag agctcagttg atgtcgaagt 724741 caatatcacg tcctcagacg gacaggaagc ggtcattatc cgcaatgccg gagataaaga 724801 gccgactgtt cacatttatg actgatagaa aacccttgtg ccatattggc acaagggttt 724861 ttatgttaca attaacagga aaagggaaaa tattttcact tctgccgaaa cacaaatcaa 724921 ggggaggtat gttgatgctg gaaatcgtgt gaaaacaatc attatcaaat ctatagcaat 724981 gaaaggatgt tagacgtgca taaagatatc aaaaaaatat ttcatgaaga gcaggttttg 725041 gcagaagctg cagcgagata cggtttctca aaagatcagg tgcgttttct ggctgatgcg 725101 gaaaactatg tatatgaatg tatgaaagac aatcaacctt atattttaaa gattacccat 725161 acgattcgga gatcttctga ttatatgatg ggagagatgg aatggctccg tcaccttgca 725221 atagggggaa tttcagtagc caaaccgctc ccgtcgctga acggaaaaga cgtagaagca 725281 gtgccggacg gaaacggcgg gtcattttta ttgagagtgt atgagaaagc gccggggcaa 725341 aaagtggatg aatcggactg gaatgaaacg ctattttatg agcttggcag atacacaggc 725401 agcatgcaca gcctgacaaa aagctacaaa ttgagcaatc ccgctttcaa aagacaggaa 725461 tgggatgaag aggagcaatt aaagctgaga aaatatgtgc ctgaagatca gataaaggtg 725521 tttcagcaag ccgattcttt gatgaatgaa ctgcggaggc tcccgaaaag ccaggacaac 725581 tacggcttgg tgcatgcgga tctgcaccat ggcaatttta actgggatca tggcaaaatc 725641 acggcatttg attttgatga tatcggctac aactggtttg ttaacgatat tagcattctt 725701 ctctacaatg tcctgtggta tcctgttgtg ccatatgatg ataaagctgc gtttacagaa 725761 gaatttatga cgcattttat gaaagggtac tgggaggaaa atgagcttga ccctgcatgg 725821 ctgatgataa tacctgattt cctccgcctt cgccatatgc tgatttacgg attgctgcat 725881 cagatgtttg accttaacac aataggagaa gaggaaaaag aaatgctggc cggtttcaga 725941 agagatatag agaatggcac gccgattaca gcatttgatt tttcagcact ggtgtagata 726001 gaaaaagcca atgggattcc agtcccattg gcttttataa tgtatcacac ttcacgccga 726061 ctacgccttc aatggcttta atgtcatagt agacatcggt cgtgtatctg tttttatgga 726121 cgcggacctt cacttccata attggaaaat ccttttcgcc taggtcgtcg atccgaacgg 726181 agtgtgcttt gatatctctt cttttcattt cttttaaaat ctctgtcatt ttgtctttat 726241 cagaaagtga cattctgatg cggatgtctt tttcctgcag gcggtcgggg ccgatttttc 726301 tgaccaccca tgggagaaat tccacactga tcaggatgaa cagaagactg gcaaacgctt 726361 ctttataaaa accggctccc gtagcaagcc cgagccccgc tgccccccag atcatggccg 726421 atgtcgtcag gccggaaatg acatcattgc tttttcgcag gatgacaccg gcgccgataa 726481 acccgacgcc ggagatgatt tgtgccggca gacgaagcgg atccatcatg atgcggtagt 726541 atttagggaa atgatatgcc gcattaatac tgacgatcgt cagcatgcat gagctgactg 726601 cgatgacaat acaggttttt aatccgagcg gcttattttt taattcgcgt tcaagcccga 726661 tgaccatgcc aatcaatgtg gcaatgccca atttcaataa aatatcagga tcaatatacc 726721 agctcaacag caaacttccc ccttctctat ggtgttttta aataaatatg attttctcac 726781 agtatttata gcaaaacaag agcacaaaag ccaccaagct gcgcttgatg gcttattgct 726841 tactttttgc gttttaacag cttttccatg acaccgaata atcggtaaga ggcttttgca 726901 ggacgttttg tgatcatgct gacaatgatg ccggcaatca tactgagaat aaacccaggg 726961 atgatttcgt acacaccggt tgattttgcc aggccggttg taatccagat caacacggtc 727021 gcagccccga caatcatggc agcaagcgcg ccccattcgt tcattcgttt ccaatacaga 727081 ctgagcagaa tcgcaggccc gaaagctgaa ccgaagccgg cccaagcgta tccgaccaaa 727141 tcaagaatgg tgctgttcgg gttcaatgac aagagtaccg cgataacggc aatgactaag 727201 acggacaatc gcccgatcat gaccaattct ttatcagaag cttttcgtct gaaaaatgac 727261 cggtataaat cctctgttac agcacttgct gtgaccaaga gctgtgagga aatcgaactc 727321 atgatggcag ccaaaatagc tgacaataag aaccctgtaa ttaatgggtg gaacaagatt 727381 ttagagaaga taatgaaaat catctccgga tcttttacag caactccgaa tttatgggcg 727441 tatgcaacac cgattaaacc cgtcagcacg gaacctagaa ctgtaatgat catccagctc 727501 atgccgattc ggcgtgcagg ttttaaatct ttaatgtctt taatggccat aaatcggacg 727561 atgatatgag gctggccgta gtagcccaac ccccaggcta aataggaaat aatgctaatg 727621 acgctcgcgc ctttaaaaat atccaataaa tgtggattaa cagcgtcgat ttcatggaaa 727681 gtcggagcaa cgccgcccac atgggtaaaa gcaacgatcg gcacaagcac tagtgctgca 727741 aacatgatcg caccctgcac gaagtcagtc agactgacag caaggaaacc gccaaacagt 727801 gtgtataaca cgacaactgc ggtggtcaga aacaggccta atttgtaatc cgcaccaaaa 727861 gcagattcaa acagccgtcc gccagatacc ataccggaag aggtatacaa tgtgaaaaag 727921 atcatgatga tcaatgcaga tacgattttc agcagtgatg aagaatgctg gaatcgttta 727981 tcaaagaaat caggaattgt aatcgcatca tctgccgctt ctgtataagc acgcagcctt 728041 ggagccagca gcaagtaatt tgagtacgcc ccgattgtaa gacctaaagc aagccataag 728101 gtggacagcc ctgtcgcaaa catcgcgccg ggaacaccca tcagcatcca tccgctcata 728161 tcggccgcgc cggcagacaa agcagtaacg aatggtccga ggcctcttcc tccaagcatg 728221 taatcattga tgtcagtggt tttcttgaat gcataccagc cgattaacag catggcaata 728281 aagtaaattc ctaaagatat aataatttca atactcacgt tttaccctct cttcatttct 728341 aataatgttg catcacctct caaattgatg gtgccagtta agcagcctgg cgtaagtgca 728401 aaacaaaaga aattcttttg cgggtgcact tggtaactta acctaacaaa gtattcccgg 728461 ccattcaagc gatgaaacat tgatcataag ctggaaatac cgttgcaaac ctagaaggga 728521 ataaagaata aaacgctttc aaaaaataat taaagtaaaa atattcagaa aaatatttcg 728581 tttctccttc tcctcatttt agtataaaat atatagggta ttgtttcgaa aacacaggcc 728641 tgtctcaagg cgttttgttg ctttaaaggg cttgtttttg atatgatcag tattatatga 728701 cttaacggag aaatatgtgg aggtggatca tatgtcacga atttcaatag aagaagtaaa 728761 gcacgttgcg caccttgcaa gacttgcgat tactgaagaa gaagcaaaaa tgttcactga 728821 acagctcgac agtatcattt catttgccga ggagcttaat gaggttaaca cagacaatgt 728881 ggagcctaca actcacgtgc tgaaaatgaa aaatgtcatg agagaagatg aagcgggtaa 728941 aggtcttccg gttgaggatg tcatgaaaaa tgcgcctgac cataaagacg gctatattcg 729001 tgtgccatca attctggact aaaggaggga cacaagaatg tcattatttg atcataaaat 729061 cacagaatta aaacagctca tacataaaaa agagattaag atttctgatc tggttgatga 729121 atcttataaa cgcatccaag cggttgatga taaggtacaa gcctttttgg cattagatga 729181 agaaagagcg cgcgcatacg cgaaggagct tgatgaggcg gttgacggcc gttctgagca 729241 cggtcttctt ttcggtatgc cgatcggcgt aaaagataat atcgtaacaa aagggctgcg 729301 cacaacatgc tccagcaaaa ttctcgaaaa ctttgatccg atttacgatg ctactgtcgt 729361 tcagcgcctt caagacgctg aagcggtcac aatcggaaaa ctgaacatgg acgaattcgc 729421 catggggtca tctacagaaa actcagctta caagctgacg aaaaaccctt ggaacctgga 729481 tacagttccc ggcggttcaa gcggcggatc tgcagctgcg gttgctgcgg gagaagttcc 729541 gttttctctt ggatctgaca caggcggctc catccgtcag ccggcatctt tctgcggcgt 729601 tgtcggatta aaacctacat acggacgtgt atctcgttac ggcctggtcg catttgcgtc 729661 ttcattggac caaatcggac cgattacacg tacggttgag gataacgcgt ttttacttca 729721 agcgatttcc ggcgtagaca aaatggactc tacgagtgca aatgtggacg tgcctgattt 729781 tctttcttca ttaactggcg acatcaaagg actgaaaatc gccgttccga aagaatacct 729841 tggtgaaggt gtcggcaaag aagcgagaga atctgtcttg gcagcgctga aagtccttga 729901 aggtctcggc gctacatggg aagaagtgtc tcttccgcac agtaaatacg cgcttgcgac 729961 atattacctg ctgtcatctt ctgaagcgtc agcgaacctt gcacgctttg acggcatccg 730021 ctacggctac cgcacagaca acgcggataa cctgatcgac ctttacaagc aaacgcgcgc 730081 tgaaggtttc ggaaatgaag tcaaacgccg catcatgctc ggaacgtttg ctttaagctc 730141 aggctactac gatgcgtact acaaaaaagc gcaaaaagtg cgtacgttga ttaagaagga 730201 tttcgaggac gtatttgaaa aatatgatgt tattgttgga ccgactacac cgacacctgc 730261 gtttaaaatc ggtgaaaaca cgaaggatcc gctcacaatg tacgcaaacg atatcttaac 730321 gattccggtc aaccttgccg gcgtaccggg aatcagtgtg ccatgcggat tagcagacgg 730381 acttccgctc ggcctgcaaa tcatcggaaa acactttgat gaaagcactg tataccgcgt 730441 tgctcatgca tttgaacaag caacagacca tcataaagca aaacctgaac tgtaaggggt 730501 gaaaagaatt gaactttgaa acggtaatcg gacttgaagt ccacgttgag ttaaaaacaa 730561 aatcaaaaat tttctcaagc tctccaacgc cattcggcgc ggaggcgaat acgcagacaa 730621 gcgttattga cctcggatat ccgggcgtcc tgcctgttct gaacaaagaa gccgttgaat 730681 tcgcaatgaa agccgctatg gcgctcaact gtgagatcgc aacggatacg aagtttgacc 730741 gcaaaaacta tttctatcct gacaacccga aagcgtatca gatttctcaa tttgataagc 730801 caatcggcga aaacggctgg atcgaaattg aagtcggcgg caaaacaaaa cgcatcggca 730861 tcacgcgcct tcatcttgaa gaggatgccg gaaaactgac gcatacgggc gacggctatt 730921 ctcttgttga cttcaaccgt caaggaacgc cgcttgttga gatcgtatca gagccggaca 730981 tccgcacgcc ggaagaagcg tacgcatatc ttgaaaagct gaaatccatc atccaatata 731041 caggcgtttc tgactgtaaa atggaagaag gctcacttcg ctgtgacgcc aatatctctc 731101 ttcgtccgat cggccaagag gaattcggca caaaaacaga attgaaaaac ttgaactcct 731161 ttgcgtttgt tcaaaaaggc cttgagcatg aagaaaaacg ccaggagcag gttcttcttt 731221 ccggcggcgt catccagcaa gaaactcgcc gttatgatga agcaacgaag aaaaccattc 731281 ttatgcgtgt caaagaggga tctgacgact accgttactt cccagagcca gatctagtcg 731341 agctctacat tgatgatgaa tggaaggaac gcgtaaaagc aagcattcct gagcttccgg 731401 atgagcgccg caagcgttat atcgaagagc ttggcttgcc tgcatatgac gcaatggttc 731461 tgacgctgac aaaagaaatg gctgatttct tcgaagaaac cgttcaaaaa ggcgctgaag 731521 ctaaacaagc gtctaactgg ctgatgggtg aagtgtcagc ttacctaaac gcagaacaaa 731581 aagagcttgc cgatgttgcc ctgacacctg aaggccttgc cggcatgatc aaattgattg 731641 aaaaaggaac catttcttct aagatcgcga agaaagtgtt taaagaattg attgaaaaag 731701 gcggcgacgc tgagaagatt gtgaaagaga aaggccttgt tcagatttct gacgaaggcg 731761 tgcttctgaa gcttgtcact gaggcgcttg acaacaatcc tcaatcaatc gaagacttta 731821 aaaacggaaa agaccgcgcg atcggcttcc tagtcggaca gattatgaaa gcgtccaaag 731881 gacaagccaa cccgccgatg gtcaacaaaa ttctgcttga agaaattaaa aaacgctaat 731941 aaaaaagcag cccttagagg ctgctttttt tatggtcaaa ttgagataaa gacaagatga 732001 gggcccgaag cctttcaact tctttgtcgt tggttccggc caaattggac agcatgcctt 732061 taataatcgg cttgcgcggt ttatcctgag tcaattcttc ctcgataaca tcaagtgaca 732121 cggtgatatc ctcgggcagc gtgctgtttt ctttcacttt ctgaatgtcc tcaagcagct 732181 ggtcttttcc cgcaggcatc gggttaaaaa tgtcttttga tacaatcgga ttgagtgcag 732241 aacggctcag cccctgtaca agatcatcca gtctctcaat aataaaggct gagatttctt 732301 ctgcatcgat attaagctca ccgttaaata ccatcacgtt catataggaa tgcacaatgc 732361 ctcttgccat gatggacaga tctgcgacat accgctcgat tccttcgcca taggatacca 732421 gcaaggcgtt ccggtacagc ttatccgtct ccatggttac tttgtaaaag tattgcttga 732481 tttcttgatt ttccggaatg atattttcgg taagcaaaag aacgataaaa tctttatgat 732541 cgcgaaaatc ctcaaattga gcgccaattt gcttttttaa cacttcctta ggcggctttc 732601 cggcgagatc ttcttctata tttttcattt tgttcataga cataccgata taatattcac 732661 aggcagataa cagcagcgct tctttcgatt tgaagtgcaa ataaaaagcg cccttcgaaa 732721 tgccgcattc actggcgatt tcttggatcg tcgtagctgc gaatcctttt ttcgcaaata 732781 aacgaatgct ggtttttatg attctctctt ttttttcatt catgacgtgc ttccccttaa 732841 tccttgaaaa atttagtaaa attttctggt atatgagttg acgttgttgc gttataacgt 732901 ttagtattat atagaatgac cagtcagtca ataaaaaatg taatggagga tatgatgaac 732961 cacgttatta atttcgttct gaaaaacaaa ttcgccgtat ggctgatgac gattattgta 733021 acggcagccg gcttgtatgc gggtatgaat atgaagcaag agtctattcc tgacgtgaac 733081 atgccttact tgacgatcag cacgacatat ccgggtgcaa caccaagcca agtggctgat 733141 gaagtgacca aaccggttga acaagccgta cagaacttgg acggtgtcag cgttgtgacg 733201 tcgacgtcct atgaaaacgc atcgtcggtc atgattgaat atgattatga gaaagatatg 733261 gacaaagcga aaacagaagc agctgaagcg ttagaaaacg tcaacctgcc tgatgacgcg 733321 aaggatccgg agatttcacg ctacagcttg aactcattcc cgattctgac gctgagcgtg 733381 tccagtgata aagataatct gcaagagctg acgaaacaag tggaggacag cctcgtttct 733441 aagcttgaag gcatagaagg cgttgcgtcc gtccaagtat caggccagca ggtggaagag 733501 gttgaattct ctttcaaaga agacaaactg aaggaatacg gccttgatga agatacagtc 733561 aagcaagtga ttcaaggttc agatgtgaca actccgcttg gattgtacac attcggaaat 733621 gaagaaaaat ctgtcgtcgt cagcggcgat attgaaacaa ttaaagattt gaagaatatg 733681 agaatcccga cggcatctgc ttcaagtgca ggcagcagcg cagcatctca agcaggtgcg 733741 cagagtgctc aagcagccca aagcgcgcaa gcggcagcac aggtgcagca aagcgcaagc 733801 acagcagtgc cgacggtcaa gctttctgac attgctacaa ttaaagatgt gaaaaaagct 733861 gaatccgttt cacgcacaaa tggcaaagac agcatcggca tcaacatcgt caaagcaaac 733921 gatgcgaata cggtagaggt tgccgacgat gtcaaagctg agctgaaaaa gttcaaagaa 733981 gaccataaag gcttcaatta cagcgcaact ctcgacatgg cggagccgat cacacagtca 734041 gttgacacga tgttaagcaa agccatcttc ggtgctattt ttgcgattgt gattattctc 734101 ttattcttaa gagatatcaa atcaacatta atttctgttg tttcaattcc attatcattg 734161 ctgatcgcac tccttgtgct gcagcagctt gatatcacat tgaatattat gacgctcggc 734221 gcaatgaccg ttgccatcgg acgtgtagtc gatgactcca tcgttgtgat cgagaacatt 734281 taccgccgca tgagactcaa agatgagccg ctccgcggaa aagccttggt tcgtgaagcg 734341 acgaaggaaa tgtttaaacc gatcatgtca tcaacgattg tgacaatcgc ggtattcctg 734401 ccgctcgcac ttgtaggcgg acaaatcggt gaattgttta ttccatttgc cttaacgatt 734461 gtttttgcgc ttgccgcatc cctagtgatt tcaatcacgc ttgtgccgat gctcgcacac 734521 agcctgttca aaaaatcatt aaccggtgcg ccgattaaag cgaaagaaca caaacctggc 734581 agacttgcaa acatctataa aaaagtattg aactgggcgc tgagccacaa atggatcacg 734641 tctatcatcg cggttctgat gctccttgga agcttgttcc tcgtaccgtt aatcggtgcc 734701 agctacctgc cgtccgagga agaaaaaacg atgcagctca catacagccc agaaccgggt 734761 gaaacgaaaa aagaagccga aaatgaagct gaaaaagcgg aaaaaatcct gcttgaccgc 734821 aagcatgtcg atacggttca gtattcatta ggctctggca gcccgcttgc cggaggagat 734881 tctaacggtg cgttattcta tatcaaatat gaaagcgaca cacctgactt tgataaagaa 734941 aaagataacg ttctgaagga aatccaaaag caatctgacc gcggagaatg gaagtcacag 735001 gacttcagct cttcaggcaa taataacgaa ttaacatact atgtgtatgg cgattctgaa 735061 aacgatatta aagacacggt caaagacatt gaaaaaatca tgaaagatga aaaggatctg 735121 aaaaacgtaa attcaggcct ttccagcaca tatgatgagt acacatttgt cgctgaccaa 735181 gaaaaactaa gcaagctcgg tttaaccgcg tctcaaattt ctcaggcctt aatgtcacaa 735241 acatcgcaag aaccgctcac cactgtgaaa aaagacggca aagagcttga tgtgaacatt 735301 aagacagaaa aagacgagta taagagtgtg aaagatttag agaataaaaa gatcacttcc 735361 gcgactggcc aggaagtcaa aatcggcgat gtggcaaaag tgaaagaagg atcaacatca 735421 gataccgtgt caaaacgtga cggaaaagtc tatgcagatg tcacaggtga ggttacctct 735481 gacaacgtca cagccgtatc agctgctatc cagaagaaaa tcgataagct tgaccaccct 735541 gataacgtat cgattgacac aggcggcgta tcagcggata tcgctgattc cttcacgaag 735601 ctcggtttag cgatgctggc agcaatagcg atcgtttacc ttgtgctcgt gattaccttc 735661 ggcggagcac tagcgccatt tgcgattctg ttctcattgc cgttcacagt catcggtgcc 735721 ctggtcggac tttacgtatc aggtgaaacg atcagtctga acgccatgat cggtatgctc 735781 atgctgatcg gtatcgttgt cacgaatgcc attgtcttaa ttgaccgcgt gattcataag 735841 gaagcggaag gcctgtctac gagagaagcg ctcctggaag ccggctctac acgactccgt 735901 ccgatcctga tgacagccat tgcgacaatc ggcgccttga ttccattagc cctcggcttc 735961 gaaggcggaa gccaggtcat ttcaaaagga ctcggcgtaa cggttatcgg cggtttaatc 736021 agttcaacgc ttctgacgct cctgatcgtg ccaatcgtat atgaagtatt ggcgaagttc 736081 cgcaagaaaa aaccgggaac ggaagaagag taaaaaacaa aaagcctcag ctctgctgag 736141 gctttcagct tgttgaaaaa ccctcgcatt cgttgtcagg tctgcgcgtc ggtgctcacg 736201 aattctacat tcgctccgct ccaatgctcc cccttcctag actacaaggg ttttcaatca 736261 agctgaaaga atgttaagga tgacaaaagc tcaaaacaag aatcagtttt gagcttttgt 736321 gcgttttcac ctgtaagatt atgtacattt tgttgcgatt tttttaactc atagtataat 736381 taaaggttgt tagtgtaaaa atggatcgga tactcttaag taggatgatg agataatgaa 736441 acgtgcacgc ataatataca atccgacttc aggacgggag atctttaaaa agcatcttgc 736501 ccaggtcctg caaaaatttg aacaagccgg ctatgaaacc tccacccatg cgacgacatg 736561 cgcaggagac gctacacacg ctgccaagga agcggcattg cgtgagtttg acctgatcat 736621 tgcggcaggc ggagacggaa cgatcaacga ggtcgtcaac gggcttgcgc ctttagacaa 736681 tcgtccgaca ctcggtgtga ttcctgtcgg cacaacgaac gacttcgcca gagcgctcgg 736741 aatcccacgc gaggatattt taaaagcggc agatacggtc attaacggcg ttgcccgccc 736801 gattgatatc ggacaggtca acggccagta ttttatcaat atcgccggcg gaggccgtct 736861 gacggagctg acgtacgacg tgccaagcaa actgaaaaca atgctcggcc agcttgctta 736921 ttatttaaaa ggaatggaaa tgctgccttc acttcgtccg acagaagtcg agattgaata 736981 tgacggcaag ctgtttcaag gtgaaatcat gctgtttttg gtcacgctga caaactccgt 737041 cggcgggttc gaaaagctcg cgccggattc cagcctgaat gacggcatgt ttgatttgat 737101 gatactaaag aaagcaaacc ttgctgaatt tatcagggtc gccacgatgg cgcttcgcgg 737161 agaacacatc aacgaccagc acattattta tacaaaagcg aaccgcgtga aagtcaatgt 737221 atcagaaaag atgcagctga acctggacgg cgagtacggc ggcatgctgc cgggcgaatt 737281 cgtgaatctg taccggcaca ttcacgtcgt catgccgaag gagaaagcgg aacagttgga 737341 tgactaaaac ttggcttggt aagccaagct cagaatgttg acaaaatcct aaaacagttt 737401 tcgttttagg attttgtcat cttttcagcg tgattgaaaa cctttgaagt ctaggaaggg 737461 cgagcatcgg agcacagcga atgttgaatt cgtgagcacc gaagcacagg cctgacaacg 737521 aatgcgaagg tttgcctaca cgctgaaact tggcttgaat aggccaagtt tttctttcgc 737581 ttaaaactag aggtgattat agatgaaaat gaaaccccca gtagaaaaaa atgaatacta 737641 cgatgtgaca tttgaggatt tgacacatga aggagcgggc gtcgcaaagg tccaaggctt 737701 cccgatcttt gtgccgaatg ccctacccga ggaaaaagcc caaatcaaag tgacacgcgt 737761 caaaaaaggg ttcgccttcg gccgcctgat tgagctgaag gaagaaagcc cgcatagaac 737821 ggacgcccca tgcccgattt acaaacaatg cggaggctgc cagcttcagc acatgaccta 737881 cgaaggccag ctcctgttta aacagaaaca agtcaaagac gtcttagaac gcatcggcaa 737941 gctggacctt tcaaaagtca ccgtgcaccc gacactcggc atggaagacc cgtggaacta 738001 cagaaacaaa gcacaggtgc cggtaggaga acgggaaggc ggactcgtcg cgggattcta 738061 tcagcaaaga agccatgaca tcatcgacat gagcgcctgc ctgatccagc aatccaaaaa 738121 cgacgaagcc gttcaagctg tcaaagacat ttgcgcaaac tacggtgtca aagcctacaa 738181 cgaagaacgc cacaaaggct ggctccgcca catcatggtc agatacggcg ttgttacggg 738241 cgaaatgatg atcgtcttca tcacaagaac aagcgacttc ccgcacaaag cgaagatcat 738301 cgaagacatc acagcgcaat tcccgcacgt caaatccatc gtgcaaaaca tcaacccaaa 738361 caaaacaaac gtcatttttg gcaacgaaac aaacgtcatc tggggcgaag aatacatcta 738421 cgacctcatc ggagacgtca aattcgccat ctccgccaga tcgttttatc aggtcaaccc 738481 agagcaaaca aaagtgctct acgacaaagc gcttgagtac gctgagcttc aaggggaaga 738541 aaccgtcatc gacgcttact gcggcatcgg aacgatttct ctcttcctgg caaagcaggc 738601 gaaaaaagtg tacggtgtag agattgtgcc ggaagcaatt gaggacgcga agcgaaacgc 738661 cgaattaaac ggcaacacaa acgcagagtt tgctgttgga gaagcggaaa ccgtgattcc 738721 aaagtggtac gaagaaggca ttacagctga tacgctggtc gtcgacccgc caagaaaagg 738781 ctgcgacgaa gccctcctgc ggacaattgt ggagatgaag ccgaagcggg tagtgtatgt 738841 gtcctgtaat cctggcacgc ttgcgagaga tttgcgggtg cttgaggatg gcgggtacgt 738901 gacgcgcgaa gtgcagcctg tggatatgtt tccgcatacg aatcatgtgg agtgctgtgt 738961 gttgataaaa ttaaaagaat aaatagtcaa aaatctatgc tgatggaact gttggttctc 739021 taaaacgata attgatttca atggttccat ttgcatgtac ttctatttca tctactaaca 739081 aatgaagcat ttcgggggta agtgtacctt ccttcatgaa tttatctaag ctctttttaa 739141 aatcaattat ttctttttca atcttttgaa attctaggtc cttagatagt tggtgaaggg 739201 tagtttcaaa atttgaaata tcttcattgg tgatatttat ggctaattgg taatcttctt 739261 tagatataac accattagca agagagataa ctaaattgga tttatctctc tttttatcgt 739321 ttaatttttc attaatttcg attatcttag attcgatttt ttctttgtac tttaacgctt 739381 tttcacttaa ttctttaaaa taattttcct tactgaattt caaatatatc ttatttaggt 739441 tggttattac tttatcagtt aaatctattt cacttacgta atgatcacta catgctttta 739501 aaccatgttt attataactt ccacaaacat aaccttttcg attcttttta aaatgcattg 739561 acctcctgca atctttgcaa accgcagtat ttgtaaagag atgtacttca gcttgaggtc 739621 tccttctttt tctagttatt aaaatctctt gtacaataag aaagtcttct aaaggtatga 739681 ttggttcgtg gcttttttca ataattattt ggttttctag gttaactgac cttcttcttt 739741 tactggtaac actcggtcta tattctctac attgttgtag tgtcccagta tagtgaggat 739801 tttcgagaat ttttcttatt gaagatccgt gccatttgtc agtagcgttc tttttgcggg 739861 caagctgcga gggactagtg accccttcgt tatacaatcc ccttgctatt gcatcaaagc 739921 cttttccagc aatatattct gaaaagattc taatatttac tattttctct gcgtttgctg 739981 aatttgagag agatatgatt gtagaacgaa ctcaagaagg taaaatgttg gccaagcaga 740041 atccggattt ccgagaagga agacccaaaa agttcacaaa gcagcaaatc aatcatgcat 740101 taacattact agaaaatcat tcgtataaac aagttgaaga tatgactggg atatcagttt 740161 ctacacttgt aagagctaaa aagaagaaag ctgctgaagc tataaatgga taaatattgt 740221 gaattaatta ttcaatatct tgagaaattt ttataaaagt aatcaaaagt ttaatggggg 740281 aaacgaaatg gcgctcattg atttagaaga taaaattgct gaaatagtga atcgagaaga 740341 tcattcagat ttcttgtatg aattactcgg tgtatatgat gttccacgag ctacaattac 740401 gcgcttgaaa aaaggaaatc aaaaccttac aaaacgggtt ggtgaagtac acttaaagaa 740461 taaggtgtgg tttaaggagg ctaagaaagg aaagctcttt gacgccctta ttgatataga 740521 acaacaagtt gaatatcttt cagctaagcc acgatattta ttagttactg actatgatgg 740581 agtattagcg aaagatacaa aaacattaga ggctcttgat gttaaatttg aagaacttcc 740641 tcagtatttc gatttcttcc ttgcttggaa aggtattgag aaagtagagt ttgaaaagga 740701 aaaccccgct gatattaaag cagccgaacg ttttgcacgg atatatgatg tacttcgtaa 740761 agaaaacaat attattgaga ctaatagagg gttagattta tttcttattc gtttactgtt 740821 ttgttttttc gcagaagata ctgacatctt caaacgaaat agttttacga atttaattaa 740881 gactttgact gaagaagatg gttcaaatct aaataaatta tttgctgatt tatttatcgt 740941 gttagataaa aatgaacgag acgatgttcc atcttattta aaagagtttc cgtatgtaaa 741001 tggccagttg tttactgaac cacatacaga gttggaattt tctgccaaat ccagaaagtt 741061 aattattgag tgcggtgaat tattaaactg ggctaaaatc aatcctgata tctttggttc 741121 aatgattcaa gctgttgctt ctgaagaaag ccgtagttat ttaggtatgc actacacaag 741181 tgtccccaat ataatgaagg ttattaaacc gcttttccta gataaactta atcagtcttt 741241 tttagatgca tacgatgatt atacaaaact tgaaaatctt ctaacacgaa tcggcaaaat 741301 taaattcttt gatcctgcat gtggttcagg gaactttttg attattacct acaaagaatt 741361 acggcgtatg gaaatcaata ttataaaacg acttcaagaa ctcttgggag agtatcttta 741421 tgtaccttca gtaactttat ctcaatttta cggaatagag attgaagatt ttgcacatga 741481 cgttgcaaaa ttatcacttt ggattgctga acatcaaatg aatgaagaat taaaaaatga 741541 agttcataat gcagtacgcc caacgttacc acttcataca gcaggggata ttcgttgtgc 741601 aaatgctatt agggttgagt ggactgaggt ttgtcccgca caaggatctg aagaagtata 741661 tgtttttggt aatccaccgt atcttggttc aaaaaaacaa aacaaagaac ataaatctga 741721 tatgttatca atttttggaa aagtcaagaa tggtaaaatg cttgattata tttctgcttg 741781 gttttacttt ggtgctaaat acgcttcaac tacaaatgca aaagttgcct ttgtatcaac 741841 aaattcagtt actcaagggg aacaggtttc tatcttatgg aatgagttat tcaagtttgg 741901 aattcaaatc aattttgcct ataaatcttt taaatgggcg aataatgcta aaaataatgc 741961 tgcggtaatt gttgtgattg taggttttgg cccgttagat accaaagtaa acaagtattt 742021 atttgttgat gaaacgaaaa agctagtttc taacattagt ccctatttaa ctgatggtga 742081 aaatattctt gtttcttcta ggacgaagcc aatttcagac ttacccaaac tgcattttgg 742141 gaacatgcct aatgatggcg gaggattact ctttaccatt acggaatata cagacgcaat 742201 caataagtat cctgaattag ttccctattt taaaaagttt ataggttcag tagagtttat 742261 taatggtggt ttacggtatt gtttatggct taatgaagca aaatatgaaa aaataaagtc 742321 taatcctcta atacaagaaa gaatctcaat ttcaaaaaat cacagggaaa aatcaacaga 742381 taaaggaacg aataaacttg cattaactcc gtggaagttt agagatactc atgaaacaac 742441 taattattcc attgttgttc catctgtgtc ttctgaaaat agattttata ttccaatggg 742501 attagcaggt gcagatacaa ttttgtcaaa tctaatttat gtaatttacg atgcagaaat 742561 ttaccttcta ggcattttga tgtcacggat gcatatgact tgggtaaaag ctgtagccgg 742621 aagattaaaa actgactata ggtactctgc aggtttatgt tataacactt tccctattcc 742681 tgaattatca acaagaagga agaatgaaat tgaagaagca attcttgaaa ttcttgatct 742741 tcgtgaagag cagggtggta cattagcaga gctttataac ccttcaacaa tgccaattga 742801 attaaaagta gcacatgaaa agttggatgg aattgtagaa agagcgtatc gtcaaaaaca 742861 atttgaatct gatgaagaac gcttagaagt attgcttaaa ttgtatcaag aaatgacaga 742921 acggtaggtg taaggtgtat ggaaaatata attgaaatta attataacca aactggtaaa 742981 agtaagaaaa caaatgaata cggtatgcgt gaaatgcagg caagagcttt tgaaaaacgt 743041 aactcacaat atctcttagt taaagcaccg ccagcttctg ggaaatctag agctttaatg 743101 tttatcggtt tggataagct cataaatcaa ggtttgagga aagtgattgt tgctgtacct 743161 gaacgctcta taggttcttc atttaaaaat acggatttaa aaagttatgg tttctttgaa 743221 aattggaaag ttgatcctag aaataattta actgttggcg gagataactc taaggttaaa 743281 tcttttgttc gttttatgga atcggacgat caggtgttaa tatgtacgca ctctactttg 743341 cgatttgcgt ttgaaaaaat tgatgataaa gcatttgata attgtttact tgcaatagat 743401 gaatttcacc atgtatcggc agatgtcaat tctcgattag gtgaattgtt aagaagtatt 743461 attcataatt catcagcaca tattgtagcg atgactgggt cgtatttccg tggagattct 743521 gtaccaattt tattaccaga agatgaggaa ttatttgaca aggtaactta ttcctattat 743581 gaacaacttg atggatatga atatctaaag ggatttggta taggatatca cttctatcaa 743641 ggccagtaca catcagctat taatgaagta ttggatacaa ataagaaaac aatcgttcat 743701 attccaaatg taaactcagg ggaatcgaca aaggataagt acgatgaagt tggtaagata 743761 cttgatatga ttggtgaagt tgaatatcaa gatgatgata ctggaattat ttatgttaag 743821 cgacattctg acggtaaaac attgaaaatt gcagatttag tagatgacca agttggaaga 743881 gaaaatgtcg ttgcgtattt gcgtaatatt gaagccctag acgatttaga tataattatt 743941 gctcttggta tggcgaaaga gggctttgac tggccgtttt gtgaacatac tttgacagtt 744001 ggttatcgtg gctcacttac agaaatagta caaataattg ggcgctgtac acgtgatagt 744061 tacaataaaa cctatgctca atttaccaac ctaatcgcaa tgcctgatgc aaaggatgaa 744121 gtagtgactt atacagtgaa tacaatgctt aaagctattt ctgcctcact tttgatggag 744181 caggtcctta cacctgactt taaatttaaa cgtagaagaa atgaaagtga aaaatcttct 744241 actacaggag aattattcgt taagggattg aaagaaccat caacagaaaa tgtcaaaaag 744301 attattgaaa atgatattaa tgatttaaaa gcaaaaatca tgcaagattc acaagtccaa 744361 aaaacattta gtggagaagt agatcccaaa gtattgaaca aagtgttgat tccgaaagtt 744421 attcaaaaag tatatccaaa tttatcagat gaggaaattg aggaagttag acagcacgtt 744481 gttctagata cagttatgaa aggtgctaag tctgaagttg taggaagtaa agaatttata 744541 agaatggcag ataagtttat aaacattgag gatttagata tcaatctgat tgattccatc 744601 aatccgttcc aaaaagcatt tgaggttcta tcgaaagaat tgaactcacc agtgctaaaa 744661 ctgattcagg aaactattga tgcaaaacgt attaattttg atgaagatga actagtattc 744721 atatggccaa aggtttagga attttatcgt tcaactggta gaagacctga ttcaaaatct 744781 gaagacccac ttgaaaggcg tatgggtgaa gctgtattat acatgcaaga gcttaggagg 744841 aaacgtgaaa atggcaagta atagatacca ttctattaat gaaatcatgg aaagtcagct 744901 gttttaccaa atcacaacac cacctaagaa aacacaaaaa gcccagtatg atcctgaagt 744961 tgaaaagttt ttggagatta ttgaattcgt caaagaaaat gggcgagaac cccaaaaagt 745021 ccctactgat ttaactgaaa gaagtttagc aagtcgatta attgggattc ggaaagatcc 745081 tgatcgtatg gaatatttga aagagtatga tgaaattgga ttacttgaag taagatcgaa 745141 ggaactaaca attcctaaaa tttcttcaat tgatgatatt ctaaaaagtg gcttatctgc 745201 attattaggt gataatttaa ataatgatat aactaggtca atttttgata caagttcact 745261 tcaaaaggtt acgacaatgc ctgaatacgt tgcaaagcgt aaaaaaataa aagattttgg 745321 aaagtttgaa gagctattca agaagtgcca caaggaaatt acagagggta aacgaaaaat 745381 tttaactttc aaaaatgaac aagacataca gtcaaatagt ttttatatat taaaaggagt 745441 tcttctttat gttgaagatg tgggagaacg taaaaaagca aagggaaaaa ccaatgctag 745501 acttcgatgt atatttgaaa atggaacgga atcagatatg ttactacgtt ccttatcagc 745561 ggagttatat aaacatggta gacgtgtgac cgacaatgaa gatacattgt tggataatgt 745621 tagagaagat gatgtttcga ctggctttat ttacgtacta aaatctttga gtacagatcc 745681 gcaaattagt tccattaaga atttatataa gatcggtttt acaactggtt cagtagaaaa 745741 tagaatcagg aatgcagaaa atcaatcaac ttatctttat gctccagtag aaattgtaac 745801 cacatatcaa gtgttcaata tgaatgctag caaatttgag acggcaatcc atcatgcgct 745861 agcaaataat aatttggatg tttctatttt gggggcaaat ggaaagatgt tagttcctaa 745921 agagtggttc gttgtcacac ttgaagattt acaagctgta atagatgaga ttgtgatgat 745981 ggttcatctt tatgactaaa ttagtatatt aggattttag tattaataat aattttatag 746041 tagactatga aaaaatttga tgccataaca ataacttgtt ccgctttgga gtttgtcaca 746101 attgtagaat tatgtgttgc gagtattaat aggaaggggt tgagcgaccg caaaaaaaat 746161 tttcggtgct gtccgcaaaa gggagtttgg gtgttttgcg ttatatttgg ttgtgtgaag 746221 gttagcggaa actcaattcg tgaagttagg attgcggtta ttacgactga gtagtttcgt 746281 catactcttt tagcagtttt tctgtcttat gcatttcttt gagcatcgga ttcatgtagt 746341 cgttagctga ttctagatat gctctcgtca gagtgtctag tttatttcta actttagaga 746401 ggtcttcttc gaattttcca tccgatgatt gaaggataaa ttcttttgcc tcttcatatc 746461 tttttaatat gtttttcacc attggagttg gattcttttg atttattgtt tttattacag 746521 tgattgttaa atttatttgt tttattaatt cttttcttac tgtcaaggtg atgctccttt 746581 taaatctcta ttctatttga gagttgctat atctgtttaa tggtttgata gactactcat 746641 ctttataatt tagagcaatt tttacaactt gttccgctgt gtaatcttca ttgctccaga 746701 aaattaaatc acttggtgcc ggataaggaa catttttctc taataaatcg agatattcac 746761 tgactttctc atcatctaat gttgggttca ttaattcctt tacaagaaag atcaactctt 746821 cttttgtcag tttatccatt gtttgccctc caatagattg tatctccatt gattttacaa 746881 atgactttat ttcttctgat aatgttatag gttgtttgca taatgataga taattgtctt 746941 gagaaaagtt agtctcatta tagagtttat taattgtatt tataacaata tattcatatg 747001 gaaaacctct aaaatatctt tattttagat tggtttataa aaaatagctc agcagagtag 747061 ggctgagcca ttttttaatt atagaccgag gtaactaatt acaaattctt tatcatcctc 747121 atcttcaggc aaaataccaa ggtttttata ttcccatatt gcgattcttt catatccatc 747181 taattctgag gctaaaatat catcataatt ataatctaat tggaattctc cgctacgatc 747241 caatgttagt gtaaggttag tccaaacatc atcgttatta tttctgtgtt cagttcttaa 747301 ttcttcaaaa agttctctta gttctcttaa caacgtcttg aaaatatcct tgcttacgtt 747361 gtaatggcta ggtatatctt gtgaataaat aatttgatta ttttctggtg ttctgaaatg 747421 aaaaagaacc attgtggaat catctaatac ttctgcataa agatatatct ttgtccattc 747481 accaggtatg atgtcattga gtttttctcc aataagttga tacaaatctt gcatcttcct 747541 agtttccatt cttctaaccc ccaggctgat ttttaataga gacgcttatt tcttttctgc 747601 tcccaatttt gtaggttaca tcgaaatatg atggtctaag tgaatcccca gaatagactg 747661 gttctatttg aactgctact tttttaggtg gttttttgct tagggctttt gcccactcct 747721 gctccatctc ataccatttc ccaccgctcc tattaatctg agaattcatc ggcacgatat 747781 tgtcaaactg gcctgagcct ttgaattggg tggcgattaa atggccgccg tcatcgtcag 747841 gctttcggtc ctggggcttt ccagcattcg tttgtgcata ttggtttcgt ttcgcttctc 747901 ccagctgcaa gtctgctttg acacttgtaa ttctaccata gttgtcagtc gtgtacgtgt 747961 agccttcttt tgttttgtag atgatattag gcttcagcac tttctttctg ctccatcttg 748021 cgaaatgctc gccgtatttg acggttaccg gcggtacatg tggcgctgga gttcgtcttc 748081 cgcttgatga cgttccgtat ggtttcggca ggatgacctt ggcgaatttt tgcagtcctt 748141 ctttaagcgt gaccccgttg actgcgttgt aaggaacgcc tgccggcact aaatcatgac 748201 ggggatgata cgggagaata tccgcaagtg tgagatctcc gatttgattt aacttggttt 748261 tgacgtgttt ttttgatact tcaatgcctg tgtttacttt ttgtttgatg tgatcaacgg 748321 tttgttttga gactgttatg gctttttggg ctgttgctga tttgcttgct gctgttttga 748381 ctttggtcgt cactttggcg gctgtgccag tttttgagac ggctcctacg ccttttgtgc 748441 cgacaattga tgtgacaaca gtgccaaccg catatgacac ccatcttgct cttgagtagg 748501 tgtcaccatt caccatgtct ttttgatacg attcttcgat tgccgctgaa atggcttcat 748561 acgttttgat cgggtgagcc atcgctccgg taatcgcttc aacggttcct cccggatctg 748621 tgaccatatc ccacaggcct acgaccgcgt ctttcccgga atcataaagg ccgacggcaa 748681 cccctttgaa gcctgcttca agctcacgcg tgttttcaat ttgggtgaag tatctctgtt 748741 gttcagctgt cagattttca tagccgatcg tttttgccat ttcgtagaat tcatcggcat 748801 ctgcataatc gtagtttttc agtctttctt tcagtttctc aatctcgcgt tccttcgctt 748861 cctctttctt aatcttcaag taagcctcag tccgcttttc aatgtcgcct tttttcttat 748921 gtatgtcact ctcacggtac gccttggcgt tgtagtggat gggtgtggcg tttttgcctt 748981 tacccgttgc ttcttggagc ttttggaagt cggatttgat gaattgttcg tttggttcag 749041 acagggcgta ttctgttttc aggtcttcgt ccaaggcgtc caatttttcc agtgtttttt 749101 tgcgtttgtc gttggcatcg gccagctcgt ctttgaaggt ttctgttgaa aacaggtcga 749161 gcgggaggat gtcgtcgata tcgtttagga tgtctttcat cgcttttttc tgttcggaca 749221 tgatggattt agatttttta ttggcatttg ccagttcgtg ctccaggaag gattcttcga 749281 tgtatgcgtc tgagaggcct ttgtcttcgg cggctccggc gatgctgttg aaaaatgcga 749341 ttttcatgtc gatgtagtcg atccactggt cggcgacgcc gacgtggtcg tgatagaatg 749401 ccttgatgtt gctggcgcct tttcctgaga attcactgtc actgagatca gcgactcctt 749461 ttaacgcttt tctcaagttg accatttgcg ttcttagttc tttgtactct tttgcacggt 749521 ctgtcgcttc cgaaagcagt gttttcgctt caaatacttt catgaccatt tcccttcttt 749581 tgttcgctca atatcaaaat tttaccacgg gtcgggataa ggtgggggtg agaacgtgtt 749641 ttggtggaaa aatgagtcat ttggcatgtg tctttattcg tggagggatt ggaggaaaca 749701 tggtcgaaat gatattgatt gctacacatt ttttggaagt ttgtattcta tattgttttt 749761 taaggagcat gttgatgacg aaaaaacgga ttacatttgg tttattagtt ttaatggtat 749821 gtgtcatcct gtttgttctg tatgttcagt tacgcaataa agatagtatt cctgtccaat 749881 cttccgccat tcaccccgaa gaagaccgca tcttttttat ttactccaat cctttcataa 749941 aagaaagcgt gctgctttca acctctacag gcgaacggtt taacaggcgt acgtttaagg 750001 tggcggatgt gccttatatt caaacgaaat cttatgcatc aacagacctt gtattattgg 750061 cggaacacga gcctttttac tacacgctgg agaaggatgt gatcaaagag catccgctgt 750121 cagatccatt tgcgttttgg tatgagggga aggatgtcac tattgaggcc tataatgttg 750181 atacgacggg aaatgagatc cacataaacg acagaaaaac gaaaaaggaa tataccctta 750241 ccttgcctcc gcttgtcaca atgggggcca gtgatgagaa ctttatttat atcattcaaa 750301 gcatgtctat ttacgtgatt gacagaaaaa cagaggaaat gattgagacc ctgagcttag 750361 cctcatacgc tgatcaattc gcagactcgg aggaatttat cgtcgcgagc tcggatcata 750421 aattgactgt gattgaaaaa gggacatgga agacgacata tattgcgtat cctgaagatc 750481 ttgaatatgc agatactgtg tactatgaca aagaaagcgg cagtttttac gtggcgtacg 750541 aggacaaaga gggtggagcg aacttgctgg aatatgggga ggatttttct attcacacat 750601 acagcttgaa attcccttat atggaggcga agtttaaggg gaatctattg tatatagttg 750661 cccaggaaga gcataaaaag ggcatcggcg gatacgtggg tgtgtttgat atccattcta 750721 aggagatgct ttatcagttt gatttgcctg aggaacaggt gaaggttcag gattttgttg 750781 tggttgacaa taagtgaata ctatatgaaa tagaatgaca aagacccttg cataaagggt 750841 tcttttttat gaaaaaaaca aattgacagg atgaaaaaac aatttcttcc ttctatattg 750901 ttttcaaaat ttgggattga tagaatatga catatctcat agagaaggag ggaagccgtt 750961 gagtcaagcc ataccgtctt cgcgtgttgg tgttaagatt aatgaatggt ataaaatgat 751021 tcgccagttc agtgttccgg atgctgagat tctgaaagcg gaggttgagc aggacattca 751081 gcagatggaa gaagatcagg atttactgat ctattattct ctgatgtgtt ttcggcacca 751141 gctgatgctt gattatttgg agccgggaaa aacatacggg aatcgcccta cagtgacaga 751201 gcttcttgaa acgatcgaga cccctcagaa aaaactcaca ggtcttttga aatactactc 751261 tttgtttttc cgcggcatgt atgaatttga ccaaaaagaa tatgtggaag cgatcggata 751321 ttatcgcgag gcggagaaag aactgccgtt tgtgtcagat gatattgaga aagcggaatt 751381 ccattttaaa gtggcagaag cgtattatca catgaagcaa acccatgtgt cgatgtatca 751441 tattcttcaa gccttggaca tttatcaaaa ccatcctcta tacagcatta gaacgataca 751501 aagcttgttt gtgatcgccg gcaactatga tgatttcaaa cattatgata aagcgctccc 751561 gcatttagag gcggcgctgg aattggcaat ggacattcaa aatgacaggt ttatcgccat 751621 ttctctattg aacattgcaa acagctatga cagatcagga gacgatcaga tggctgtaga 751681 acatttccaa aaagcggcga aagtaagcag agagaaagtg cctgatctgc ttccgaaagt 751741 cttgtttgga ttaagctgga cattatgtaa agcgggccaa acacagaagg cgtttcagtt 751801 catagaggaa ggattagacc atatcacagc acgttctcac aaattttata aagaattgtt 751861 tctgttcttg caggccgtgt acaaggagac tgttgatgaa cgaaaaattc atgatctttt 751921 aagctatttc gaaaaaaaga acctgcacgc ttacattgaa gcatgtgccc ggagtgctgc 751981 cgctgttttt gaaagcagct gtcactttga acaagcagct gcgttttatc ggaaagtgct 752041 gaaagcccaa gaagatattc taaaaggaga gtgtttatat gcctattaag aaaaaagtga 752101 tgatgtgtct ggctgttact ctagttttcg gaagcatgtc gtttccaacc ctgacaaact 752161 ccggtggatt taaggaatcg acagatcgaa atacgacgta tatcgatcat tccccttaca 752221 aacttagtga tcagaagaaa gcccttagct agggcttttt cttgctttac ggaagacgtt 752281 ccattttcca catcgcggca ttccttctat ttctaacgca agacactcga aacaaccaaa 752341 ccatttgagg tataatggat aaagtgaata acagtattta gattgatata tatgaaagag 752401 agtggaacat catgggccgt aagtggaaca atattaaaga gaagaaggcg tctaaggacg 752461 caaatacgag tcggatttat gcgaagtttg gccgtgagat ttatgtggcg gcgaaacagg 752521 gcgagcctga tccggaatcc aaccaggcgc tgaaggttgt gcttgaacgt gcgaagactt 752581 acagcgtgcc gaaaaacatc attgaacgtg cgatcgagaa ggcgaagggc ggagcggaag 752641 agaattacga tgagcttcgt tatgagggct tcgggccgaa cggatcaatg attatcgttg 752701 atgcgctgac gaataatgta aaccgtacgg cgccggaagt gcgtgcggcg ttcgggaaaa 752761 acggcggaaa catgggtgtg agcggatctg ttgcttacat gtttgacgcg acggctgtaa 752821 tcggtgtgga aggcaaaacg gctgacgaag cgcttgaaat cctgatggaa gcggatgttg 752881 atgtacgtga cattttagaa gaggatgaca gcgcgatcgt gtatgccgag cctgatcaat 752941 tccatgcggt gcaagaggcg tttaaaaacg cgggtgtcga ggaatttaca gtagcggagc 753001 tgacaatgct tgcgcaaagt gaagtaacgc ttccggatga tgcaaaggaa cagtttgaaa 753061 aattgattga tgcattagaa gatttggaag atgttcagca ggtatatcat aacgttgatt 753121 taggtgagta aggagtgagc aggctgttat ggcctgcttt ttttgtcccg gaaattgttt 753181 tagctgtatg taggcggccg cctatacgat ctataagata ttctcatact ctggactgta 753241 acctatgtga aggagagagt aaatatgact gatacaagac atatgtatgg cggacctggt 753301 tttggtcatt atcagggctt tggtattggc cacccgggct atggcatgca aagcacaggc 753361 tatccgggct atggcatgta tggaggccac ccgggctatg gcatgcaagg ctacccagat 753421 cacggcatac atggaggagt cggcggctat ccgggatatg gtgggtacgg cggttaccca 753481 agcggcggct atggaggctc tccgggaact ggaagctatc cgagcatgca ccatgaaaat 753541 gatggccatc accactatta tcaccatcat catgatggaa aagataatct tcatcaccat 753601 catcaccatg ttggaaagga taatcatcac caccatcatg atggtcatta tggccaccat 753661 catcaccata tgggccactg gggaaaagac ggttataaat aaagaagatg atgataaaaa 753721 gaggacactc ttgcagatca agagtgtttt tttagctttt ttcttgactg ttcagtctgg 753781 aaaatggtaa catttgtttc aggaggtgat cattttttgg ggaggaataa agaatttgat 753841 acggcgcttg ttcttcacag ggcgatagag gtttttggag agtatggcta cgaaggaacg 753901 tctcttcagg atctgctctc tcatttaggc attgcgcgcc aaagtttgta tgatacgtat 753961 ggaacgaagc gtgatttgtt tttgtccgct gtgaaatcgt atcttgaagg gaaaaacgct 754021 gccgttatgg aaaggcttga agcgccagga tctgtaaagg aagccattcg tgatattttt 754081 caggagggtg tcaatgccct gagggatccg gaacgggcga aggcgtgcta cattattaac 754141 agcgcgattg aacagatccc gcatgaccct gagcttgccc ggtattttga aagacaatcc 754201 aagcagcttg aggacgcttt ttatcacggg cttttaagag cgaaggatca aggagaattg 754261 aatggcgaag atactgatat atctgcgctt gctcggtacc tgaatcagag caggctgtca 754321 ctgacattta ttgcaaaagt gacggcagat atggatcggc ttcaggacca tgttgacgtg 754381 agtttatcag tgcttgatta acatgtggta aaggattctt tgcccatgta tgtacttttt 754441 ggactgaata gtctagaaat aaaaatgagg tgatgatgaa tgttgatgaa tgagtttgaa 754501 aaagcatgtg aaacattgag aaagtttatg gcttatatgc ttgagaagga catgaagagc 754561 tggacggagc tttgggatga gaatgctgta tttgagtttc cttatgcgcc ggagggatca 754621 ccaaaaagaa tagaaggaaa agcggccatt tacgattata ttaaagatta tcctaagcag 754681 attcatcttt cttcatttac cgctccgaca gtgtaccgtt cagcagactc gaatacggtg 754741 attgcggagt ttcaatgtga cggccatgtg attgagactg gactgcctta tcgccaaagc 754801 tatatcagtg tcatcgaaac gagagacggc cgcattgtgc gttataggga ttattggaat 754861 ccgcttgttg taaaagaggc ctttggagga tcatttttgc aaacagagga gagtgggaaa 754921 tgatgaaaca gaatccgatt ttaatcacgg gcgggaccgg cacagtcggc agccgaatcg 754981 ccagccgttt aataaagctg ggatacagag tgcgtattgc aagccggaaa aagggcgcgc 755041 ttgctgatgc tgagtatgtg tattttaatt ggaagtacgc ctccagtttt acgcctgctc 755101 tggaacaggt aaaacagatc tatcttgttg ctccggtcgg tgtatttgat ccggctccct 755161 atgtgcttcc ctttttaaag gaagcaaagc gtctcggcgc aaagcgggta gtgatgcaaa 755221 gtgcgtctgt tgtctccgag aacggtcccg tgtttggcgc gcttcaccag gcagtgcgcg 755281 agtttccaga atggacggtg ctgcggccct catactttat gcaaaatttc atcaatgtcc 755341 agcaccgcat gtctattcaa acggaggggc gcatcacaac ggcttcgggt gaaggaaaac 755401 ttgggtttat tgacgctgat gacatcgcag aaacagccgt cagggctttg attgatgatg 755461 ttcctcatca aacacatcat attctgacag gtcccgaggc gctgagctat gccgaagcgg 755521 cggagatcat tggagctgcg gcgggacgcc gggtggagca tgtcagcatt tctcgttccg 755581 agctgcagca taaaatggag gcaggaggtt tgcccgcgga ttatgcccat tttatggcga 755641 agcttgatga ggcaattagc catggtgcgg aacatcgggt aacggataca gtgaagcgtg 755701 tgacgggaaa agaacctcgt tcgctgtcag agtttgcggc tgctcatgct gcatattgga 755761 cctcattttg gactgaatag tctagaaaga ccttcggcgc ttccgaaggt cttcttattg 755821 aaaaagctaa gtcgtgtttt agtcataatc atgcctcctg cctcatacct attaaggtca 755881 ttgtttttga gaaaggagga gccggaatga aggatatgca gccgtttacg cctgtcaaat 755941 catatacgcc ctttcacagc cgttttgatc cctgtccgcc catagggaag aaatattaca 756001 gaacgccccc taacctttat atgacctttc agcctgagca catggagcag ttttcgccga 756061 tggaggcttt gaggaaaggc accctttgga aggatctcta tgatttttat gaaaaccctt 756121 atcgaggggg agacgcacat ggcaaaaaag gttgacgccg aatattatcg tcagctagag 756181 caaatacagg ctgctgattt tgtgcttgtt gagctgagtc tttatttaaa tacacatcct 756241 catgatgaag atgcgttgaa gcaattcaat caatattccg gctattcaag gcacttaaaa 756301 agacagttcg aatcctctta cggaccgctt ctgcagttcg gcaacagccc cgcgggcaag 756361 gattgggatt ggggaaaagg gccatggccg tggcaagtat aaggaggaat gcctgaatgt 756421 gggtgtatga aaagaagctg caataccctg tcaaggtcag tacgtgcaac ccgacgctgg 756481 cgaagtattt gattgagcag tatggcggag cggacggcga gctggccgcg gctctccggt 756541 atttgaacca gcgttatacg attcctgata aggtcatcgg ccttttaaca gatatcggca 756601 cggaggagtt tgcccatttg gaaatgattg cgaccatggt ctataagtta acgaaagacg 756661 ccacaccgga gcagctgcgt gaagctgggc ttggcgatca ttacgtcaat cacgacagcg 756721 cgctttttta tcataatgcg gcgggcgtgc cgtttaccgc gagctatatc caagcgaagg 756781 gcgatccgat tgccgattta tacgaagata ttgccgcaga agaaaaggcg cgggcgacgt 756841 atcaatggct gattgatatt tcggatgatc ctgatttaaa cgattccctg cgttttttgc 756901 gtgagcgtga aatcgtacac tctatgcgct tcagagaagc ggttgaaatt ttaaaagaag 756961 aacgggataa aaagaagatt ttctaatagg cagattggcc tctctttcat acaccctttt 757021 acatacagag aaaatggtct gtttttgcag tttggtctgc attataatca aggtgtgtgt 757081 gcaagcttac tttttgattg ggaggccttt atgacagctt ttaagattga gaacgaaacg 757141 attgcagatg gattttacgc gtgtccggcc gtctatgagg atgcagaatc gattaccggg 757201 ttgctcgtcc gaacagctga atggctccgg gatcggggtt ctaaccaatg gagcggactt 757261 ctcaaagggc aagatataca tgatatcacg gggtcaattg aaaagggaca tgtgtttgtg 757321 tttaaaaaag atgaagagct tgcggctgtc gtgatgctgc tgcctgcacc gagcgagtgg 757381 gaccggacgc tttggggaga cgatgggcat gaggagtcca tttatttaca ccgcctcgca 757441 gtaagccgcc ggtttgcggg acaggggctt ggagcccgcg tccttcagtg ggcggagacg 757501 ggcatacact ttccggaaaa aacgcggatc cggcttgact gtgtcgctga tagtgacgcc 757561 ctgcattcct tttatcggcg tatgggatat gaattcatgg gtgctgatgc gtccggatat 757621 catttgtttg agaaagagat tacggcagaa taagcgtcct ttgcaggggg cttttttgtc 757681 tttttctaaa agggaggcag gcgatgtgtg gtcaatatta tttgtgacag ggattgtgac 757741 ggcttgtctg tttgctggcg tatccgtatt gatgcggatg agatttcctg acaaaagtcg 757801 gccggaatgg atgttggccg ggctgatcgt ccttggtgtg tttgcgatct ggtacagcct 757861 cgtgtatgta cgcggctggg aaggggctgc gctcggaatg cttggattca atgtcatttt 757921 cggagccatt gccggatatt tgatcgataa ggccatccgg cgttacagga aaagataagg 757981 ctgctgccgt ctctcaacag gtcgaaattt tcacagaccg gcaggaattt tctttcgaaa 758041 ggagaaatac atattacttt aaaatgaaag cgttttccaa agcaggaagg tgatgttgat 758101 gatacacagt gtggcaaatg ggctgaatca tttttgtacg tgggtgatga gactggccta 758161 tttgaatgtg ctttggattt tgttttctct tgcaggcctg gttgtatttg ggctgatgcc 758221 cgctactgcc gcgatgttta cagtggcgag agaatgggcg aaggggaata cagatgcccc 758281 ggtgttttct gtcttttttc ggacgtttaa aaaggaatgg cgggcatcac agatcctcgg 758341 gcttatcgtt gtgacggctg ccctgtttct gtttgcggat atgcggatag cggctcagat 758401 ggaccagcct gtgctcgtca atgtattcgt gagcattagt ttgattttcg cgtttgttgt 758461 gctgtatgtg ttcccggtat tttctcattt tgacgtaaaa atcagagagg tgctgagcat 758521 cagctttttc attgccttca gtcgtccggc ggtgacgctt ttgatggcag cgggcgctgt 758581 cggtgtgctt tgtctcgttc tgtttcatgt cacgtttcta ttgtttttca gcgggagttt 758641 actcagcctg atcttaacga agctgtcctt taaagcgttt cggtcaatgg atcagcggca 758701 ggagaaagaa aaggcggcat gaagaaaaga gttgctggct ggtacaggcg gatgaagatt 758761 aaggataagc tgtttgtgtt tctatcgttg attatggccg tatcctttct gtttgtatac 758821 agcggggtcc agtatgcctt tcatgtgtat gatgagcaga tttaccgcaa gtcctcggag 758881 gtgcttcgga tgtcttctga aaggatcgaa gacgagctga agaagataga ggatgtgtca 758941 tatgaaatca ttacagacga acagattcag cgcatcctga gcatgcaaaa tcgggatgat 759001 acgtatgatc aatatcaaat gaagcaggag ctgtgggatc agcttgcggg atatgccagc 759061 gatgaaaagt acatcgattc cattcatgtg attgatgccc gcggctcaga gtattcagcc 759121 ggaagcagtt cttcagatct tttgcagcag gagcaggaag aggtatttaa gcgagcgaaa 759181 gcgaaaagtg gaagaaatct ttggatgacg ctcggcgggt cagaccccgt cctgatttca 759241 gcacggcaga tcaggtccta tcaccagctg agtctgaacg gcttgggcat ggtactgatc 759301 caggtcaatg taaaacagat gattcgtgat gtgccgaagg attggggcga ttcagtcgga 759361 gacattatga ttgctgacca aggcggtaat ttggtgtata cggcacatgc atcagcgcat 759421 gttcctgagg cagcaaaaga gacgttgaag caccccggtt atgacttgat aaaaaagaat 759481 ggcaaacgtt actttatttc ttatcttcaa tcatcctacc aaaattggag ctactataac 759541 gttatcccct ttgatcagat gttcgcaaaa atttccttta tgaaaacagt gatcggcaca 759601 tgctttcttc tctttttctg tgtggttttg cttttcggaa ggaaaatcgc caacagcatc 759661 acggagccga ttgaacagct tgtgaccgcg atgaaatcgg tacagcacag cggcattgaa 759721 gcaggtgtgt cgctttctct gccggaacat acacaggatg aggccggcat gctgaaccgc 759781 cattttactg tcatgatgaa acggattaat gagctgatgg aagaaaatgt ggaaaaacag 759841 ctcatcatta aagaaaccga attgaaagca ctgcaagccc agatcaatcc gcatttttta 759901 tataacacgc tcgagtccat caattggctg gccaaggcga atcagcaaaa gcaaatctca 759961 aaaatggtgg aatcgctcgg ttttcttctg cgaaacagca tacatatgaa gaaggatatc 760021 gtgaccattc aggaggaggc ggacattgta cgtcactata tgaccattca gcgatttcga 760081 tttgaagagc gcctgaaatt cacgttggat attgacgatg aggtgaagca ttgcctcatt 760141 ccgaaactga cgctccagcc gcttgcggaa aatgcgattc aatacgcgct tgaacccttt 760201 acaaggccat gcgccatccg gattcaggcg aaaaaggcga agggctgtgt ctgtattacg 760261 gtcgaagata acggccctgg catggatgga cggattcttg aatcaacggg tggaagagga 760321 atcggacttt ggaatattcg cgagcgcatc agcctgacat tcggagagcc atacggattg 760381 cggattcata gtgagcatga aaaggggacg aggattgtga tcacaatacc gtgccgaaat 760441 gaggtggtgt gatgtataaa atactgctgg ctgatgatga gaggattatc cttgatggaa 760501 tggcgggaat cattgagtgg gagtcgcttg gcgcctcatt gatcggaaaa gcgcagaacg 760561 gacatgaagc atatgaaaag attgtacata agcagccgca tatcgtcatc acagacgtca 760621 aaatgcccgg catggacggg cttgagctga tcaaaaaggt gtcagccgtc agcccgtcgg 760681 tgcaatttat cgtcctgtcc gggtttggag agtttgagta cgcaaaggaa gccatgaaat 760741 atggggtgaa gcattatttg ctgaaaccct gcaatgaaca gcagattatc agctcgctgg 760801 aggaaatcat tgctgagctg aagcggcaag atgtgcacaa aaagaaaaca gcccatctga 760861 aacacgagct ggaccatatc cgttcctttg cagccgatca atacttggaa ggcttgatcg 760921 ccggtgtggc ccagctttct ccgccgcctt cacttgccgg aaaaaagatc cgcctcttga 760981 tcttaaaagg ggaacaatct attgatgctg cagccagaga ggcactcgga tcggcactga 761041 cagcggtttg cagcagcggt gaatggaccg tgctcgccgt agaggagaac gccgctgaaa 761101 aggtggcgga ggtttttgcg gaccgcaaga tggccatcag tcaggcggga gaactccggc 761161 acgcggggca gctgtttcgt gacacagctg aagcgtctgg tgacctgcat gggagcgcag 761221 tgatttcaaa aatgatcagg cttattgccg acgagctcgg aaatccgaat ctgtccttaa 761281 aatgggcggc gaaggatatg ctgtttatga atcctgatta tctcgggaag ttatttaagc 761341 aggaaacagg cgagaaattt tcccaatatg ttacacgggt gcgtcttgag catgcgatga 761401 agcagatgaa aataaggagg gacgtgagcg tttcagaaat tgctgaagaa atcgggtttg 761461 gcgataatcc gaagtatttc agtcttgttt ttaaaaaata taccggtctg acaccgtcag 761521 aattcagaag aaaacaggga ggcgcttccg caggatagcc atctctgttt ttttgacttt 761581 cgccactgtt ttttgagtgt ttcgccctat ccgaacgctt taaaataaaa tgtaagcact 761641 tacattaaag gggggattgg tttgaagaag atttgttacg tgctgttatc ccttgtctgc 761701 gtctttttgt tcagcggatg ttcagcgggt gaagaggcct cgggaaaaaa agaagatgtt 761761 acactcagaa tcgcgtggtg gggcgggcag ccaaggcatg attatacaac taaggtaatt 761821 gaactatacg agaaaaagaa tccgcacgtc catattgaag cggaatttgc gaactgggat 761881 gactactgga aaaagcttgc gcccatgtct gccgccggcc agcttcctga tgtcattcaa 761941 atggataccg cttacttagc ccaatacgga aagaagaacc agctggaaga tttaacgccg 762001 tatacaaagg atggaacgat tgacgtcagt tcaatcgacg agaatatgct gtcgggcgga 762061 aaaatcgaca ataagcttta tggatttacg ctaggtgtca acgtgctgtc tgtgattgcc 762121 aatgaagatt tgctgaaaaa agccggtgtg tctatcaatc aggaaaactg gacgtgggag 762181 gattacgaga agctggcgta tgatcttcag gaaaaagccg gtgtctacgg ttccaacgga 762241 atgcatccgc ctgatatttt cttcccttat tatttgcgca caaagggtga gcgcttttat 762301 aaagaagacg gcactggcct cgcgtatcaa gatgatcagc tgtttgtcga ttactttgaa 762361 cggcagctga ggctagtgaa agcgaaaacg tccccaacac ctgatgaaag cgcacagatt 762421 aaagggatgg aagacgattt tatcgtcaaa ggcaaatcag cgattacatg gaactactcc 762481 aatcaatatt tgggctttgc ccggctgaca gactcgccgc tgtctctcta tctgccgccg 762541 gagcaaatgc aggaaaaggc gctgacactg aagcccagta tgctgttttc cattccgaaa 762601 agctctgagc ataaaaaaga ggcagcgaaa tttattaatt tcttcgtgaa taatgaggaa 762661 gcgaaccagc tgattaaagg cgagcgaggc gttccagtct ccgacaaggt ggcggatgcg 762721 attaaaccga agctgaatga ggaagaaacc aacatcgtgg agtatgtaga aaccgcgtca 762781 aaaaacatca gcaaagccga tccgccagag cctgtgggaa gcgcggaggt catcaagctg 762841 ctgaaagata cgtcagatca gattctgtat cagaaggtat cgccggaaaa agccgccaaa 762901 acgttccgga aaaaggccaa tgagatatta gagaggaata attgacggga aatggggctg 762961 acgcaatgaa aaaaagccgg agtataagaa aagacaatct ggcgggatat gcttttattt 763021 ctccgtttat catcgggttc ctatgcttta cggtgattcc gatgggggcg tccctgtttc 763081 tgtccttcac gagctatgac ttgtttacgg cgccgaaatg gatcgggctc gacaacttta 763141 aggaaatgtt tacgggtgac gaaaagtatt ggcagtctct gaaggtgacg tttacgtatg 763201 tgcttgccgg ggttccgctc cgcctcggct tcgcgctttt tatcgctgtc attttaaaca 763261 atgcagcaaa aggaacggcc atttacagaa cgctctttta tctgccttcg atcatcggcg 763321 ggagcgtcgc cgtggcgatt atgtggcgca atatttttgg caatgacggg gtcatcaatg 763381 cgctgctgtt ttttgtcggg attgatcaaa aaattctttg gtaccagaat ccgacaagtg 763441 cgctgtggac attgattctg ctgtccgtct ggcagttcgg gtcgtcaatg ctgatttttt 763501 tggccgggct gaaaaacatt ccgtcttcgt atttggaagc ggcaagtgtg gatggggcaa 763561 atcgggtgca gcgtttcttc aagatcacgc ttccgatcct tacaccgatt attttcttta 763621 acctagtgat gcagacgatt tctgctttta tgacatttac acctgcctat atcatttcga 763681 agggcgaggg cgggccgctt gacgggacac ttctctattc gctctatttg ttccagcgtg 763741 cgtttaacta ttttcaaatg ggctacgcat cggcgatggc gtgggtcatg cttgtcattg 763801 tcgggctgat tacgctcata ttgtttaaaa catcgtcata ttgggttcat tacgagtcaa 763861 aggaggaatg acggatggag ccggtcaacc agcctgtcag agaagccccg gtttttgaga 763921 gaaaaaaagc cgggcgcgtc agtcccaaac gcatactgtt ccatgttttt acggcaacgc 763981 tggcggtgtt gctgctgtac ccggttattt ggctgtttgt cagctcgttt aaagaaagcg 764041 ccagtatttt tacaacctca cattctctca ttccagaccc ttttattctc agtaactatg 764101 ctgaagggtg gaagggcatt gcgggacagc cgtttctgac gtttattaaa aactcggcga 764161 ttattgtcgg gctgtcaaca atcggtgccg tcatgtcatc ggctgtcatt gcgtacggat 764221 ttgcgcgtat accgtttaag ggaaaaaaat tttggtttgc gtgcatgatg gggacgttaa 764281 tgctgcctca tgaagtgttg atgattccgc agtatattat gtttgcgaaa ttagactggc 764341 tgaattcctt taaaccaatt gtcgttccgc aatttttcgg gcatgcgttt tttatctttc 764401 tgatgatcca gtttatccgg acgattcccg aggagctgga tgaagccgcg cgaatcgacg 764461 gatgcggacg ctttgcctgc ttttggcgga tcattctccc gctgattgcc cccgcgcttg 764521 cgacgtctgc gattttctcc ttctattgga agtgggagga gctgattcag ccgctcttgt 764581 atttgaataa gccggagctt taccctgttt cacttgcgct gaagcttttt ctcgatacag 764641 agtcggcttc gaactggggc gcgatgtttg ccatgtcagc cgtctcgtta ttgcctgtga 764701 ttcttgtttt ctttttgttt cagaaatata tcgttcaggg catcagtacg accggattaa 764761 aataaaaagg agtgttgcag atggcacagc ttatctttga tgaagaaaag gtgacgtcgg 764821 ttattgaccg gatcgtgaaa cggacatttc agatggattt tgcgtgggat tggccgggcg 764881 gcgttgcgtt ttacggtgtg gcggaggcct atgaagcgac ggaaaacgag gaatatatca 764941 atctgttaaa aacgtgggtg gatgaacagc tggaggatgg gctgccgccg ctttcgatca 765001 acggagtttc cattgggcat acgcttttgt tcctccacaa ggtgacaggt gatgacgtgt 765061 atttggaaac agcggccgag atggcggaat atgtgctgca taaggcgccg cgctttggcg 765121 agggtatcct tcagcatacg gtgaatgcgg cagaatacgt attccctgaa caggcatggg 765181 cggatacgct gatgatggct gggctgttta tgctgagaat cgggcgggtc atggagcgtg 765241 aggattattt tgaagacggc ctgcgccagt ttcacggaca tgaggatgtg cttcaggacc 765301 ctgtcacgaa tttgtactac cacgcctggg acaacaaagc gcaaaatcat ctgtcgggga 765361 tttattgggg cagggcgaac ggctgggcgg cactcacgat ggcaaaggcg ctcccgctta 765421 ttgaggtgac acatccttcc tttatgatca tcgacggatc gctcagagac cagctgagcg 765481 cgcttgtccg gcttcaggat gaatcagggc tgtggcatac aattttggat gatccggatt 765541 cttatctgga ggtttcggca tcagcgggta ttgcttctgc tctgatgtcg agcggaaagc 765601 tgtatacaaa atatgtgcag aaatcgcttg ccgccatttt ggatgcagtg gaagaggacg 765661 gacgggtcag cagggtatcg gccgggacag ccgtcatgaa aaatgccgaa ggatacaaac 765721 aggtgcctta caaacgaata caaggatggg ggcagggact tgcgctgacg tttcttgctg 765781 atgttttgaa aacgaaaaaa cgcttgtatc agtaaagata gcggcggggg gagagggatg 765841 aaaaaacagc ctcaacagaa ggaacgggtt tctcgctgga agggaacgta tttcaaaaga 765901 aactttgtct tcattttgct gattgcctgt attcccggat tgctgactgg cggcgcaatc 765961 tactttcttt cgatcgacaa ggtggagaaa gagctgcaga gatcgcatga aacacaggtg 766021 gcgcgtgagg tcagccgaat ggatgagaag ctgggagtgc ttgaactggc actcacccag 766081 atggcctacg attcttcact gatgaacgga ttggccgaga gggatttgga gaaagacttt 766141 acgttctcct atcaattaac gaaaaagctg tttcttttgc gggatcagca gccgctgatc 766201 gagcaggctt ccatctttct gaacagcccc cggccacttg tgctgagccc tgaatacagc 766261 gctttgacag aacaggaggc gcttcgcaag tatcgctcgc tgcttgcctc agaccacagc 766321 atttattgga aacggtcggg aaaccaagcg atgctgatcc agctcattcc gggcgcggcg 766381 gagaaaccgt tcggcgcgat catgctggcg gttgatccga aagaaatgga atcaatcctg 766441 caaagcttgt ccccctatcc tgatggcagt gcgttgcttt tagatcaaaa tcgagaggtg 766501 ctgtttcatg agggggaaaa agattttgaa aagactttac ttcatgagat aaaaaaacag 766561 cctgctgaga acggccattt tcagatggaa tggaaaggca aggtgtattc tgtctccttt 766621 ggagaaatga accggatgca tcagcaatgg acctttgtgt cagcggcgcc tctttcagct 766681 attacagcgc cgatggtgtt tttatcaaaa gtgatcatcg tgatgctggt catttgcatc 766741 ggtttggcgg tgtgcatgac atggtatgca tcaaaaaaaa tctatcgtcc catccagcat 766801 ttgcttggct tgtttaccgg aggagagaag aaaacatggc aggcgtccgg gcaggatgaa 766861 ttcaaatgga ttgaaaagag atggcaggat ctatcccttg aaagccggaa gctccaacag 766921 cagctcctgc ggcagacgcc ccatatgaaa aagagttttt tgcagcatct cttacagagc 766981 gatttttact atgacaacga ggaaagcctc agatttcgga tggaggaggc tggctggaac 767041 atcggcggaa acgtgtttca tgtgcttgat ctacaggtga cagggctccg ctgtgaaaaa 767101 agcatcttcc gtgaaggtga tgaacagctt gccgtgttta cactgactaa tatcgctgag 767161 gaattggcgg ctaaacgcgt ttttcagctc tccatacttg atatcggccg gctttctgtc 767221 accgttcttg tgatgaaaac aaacagctct gatctgaagg cgtatataac ggagctggca 767281 cgccaatttg gagatgtaac cggactatgc ctgacctcga cattgagcag caagacggag 767341 cgtgtcacgg aaattccttc tttatttcag gatgtgaaat gcggcaaatc ccgcaggaag 767401 tttgctaacc gggatcaggt cattgatttg caggccgact tccctcggga tgagcagttc 767461 gctccttatt acccttttga gctggaaaaa caaattgttc agaccatccg gctggaaaga 767521 aaacaggaag ccaaggaact gatagatgga tgtatgaagg aactgtcgga aaaagcggcc 767581 atagacaggc atgtgcattc cgccctgatt cagctgtttt cccgcattca ggaggatatt 767641 ttgcattccg ggctcaatcc cagcgaactg tttcagcacc ggaatccgtt tcttgatatt 767701 tcagaattgc gcgaacctaa cgaagcggcg gcctggctga tggatgtagt ggtgacgcct 767761 tacctttcca agcttgaggg cagaaaaaac agacagcaaa agcagctggc agaacgtgtg 767821 attgcgatga ttcacgaaca gtatatggcg gacatttcat tggaaagctg tgccgatgcg 767881 cttggcatga attcctatac gttaagcaag gcatttaagc aagtgaccgg cattaatttt 767941 atcgattatg tgacccagat cagaatcgaa aaggcgaaag aactgctggt caatacgaat 768001 aaaaaaattc atgatgtgtc tgaagaagtc ggctatcgcc acaattattt caatcggatt 768061 tttaaaaaac aggtcggcat gccgccgggt gtcttcaggc aaatgtatca ggaaacgccg 768121 tgaaaggaga gaacatgtga tgaagaaacc gattcaagta tttttagcgg gggattccac 768181 tgtgagtgac tgcccgcctc atgaagcgcc gatggcgggg tgggggcagg tattcgggca 768241 attgttttct gaaggtgtgc tggtccgcaa tcatgccaaa ggaggagcga gcaccaattc 768301 ttttgtggag gaaggaaggc ttcaagcaat tgccgagcac atcacacaag gcgattattt 768361 gttgattcaa ttcggccaca atgaccaaaa accgcggggg acgaagccgt actccacatt 768421 tcagcagttt cttaccttgt ttgcagatac ggcacgcgaa aagggcgcgc atcctgtgtt 768481 cgtcacatcg gtgcagcgcc gccgctttga tgaaaacgga cggatcgagc atacgctcgg 768541 tgagtatccc gatgcgatga aagcactggc gaaggagctc gatgtacctg tgattgatct 768601 gcttgcgaaa acaaaggtgc tgtatgaagc atacgggccg gaggagtcga agcgattgtt 768661 cgtttggttt cagccgaatg aacatccgaa ttacccggac ggcattgagg acaatacgca 768721 tttttcggaa aaaggtgcaa tggaggttgc gaagcttgtg gcagaaggca ttgaagagct 768781 cggacttccg cttaaggacc accttgtgag ccgggaggga aaagaacatg tataaggaag 768841 gcgcttgctt gtaccgcaat ccgctccggt ctaaaagcga tgtgaaggat tggcggatgg 768901 agggaggcgg acagatctca tttgacgatc acagcttgca cctgtcacat gtccaggatg 768961 aagcgcactt tgtcttttgg tgtccggaaa cctttccaga cggcatcatt gtgacatggg 769021 acttctctcc gatcgagcag cctggactgt gtatgctgtt ttttgccgct gcgggtattc 769081 gcggcgagga tttgtttgac ccaagtctca ggaaaagaac aggaacatac cctgagtatc 769141 attcaggaga tatcaatgcc ctccacctgt cgtatttccg cagaaaatac gcggaggaaa 769201 gagcgttccg cacctgcaat ttaagaaaaa gccgcggttt ccatctcgcc gcaatggggg 769261 ccgatccgct gccttctcca gacgacgctg attctccgta tcgtatgaag ctgatcaaag 769321 acaaaggcta tgtgcacttt tcaatcaatg gtctgcccat tcttgagtgg atggacgacg 769381 gcagcacata tgggcctgtg ttaacaaaag gaaaaatcgg gttccggcag atggccccca 769441 tgaaagccgt ttacagggat tttgccgtgc atcaagcggt gagaagatga agacgactgt 769501 aacggatgcg ctttatgcag gctgcgaagc ggtggtgaaa atagcatggc tcaacgggct 769561 gtggctgttg tttacacttt tgggcggcgt tcttttcgga tgggcgccga gcacagctgc 769621 gatgtgtgcc gttataagga aatggctgat ggggcaaaag gatgtcccga tattttcgtt 769681 atttctcgat acctataaaa aagagtttct caaggttaat gcgatcggat tggcgttttc 769741 ggctcttttg ctcatattgt ctgccaacta tcattatttt tctgccagta cgaattggct 769801 gtcctttgcc gtaacaagct gcacgctgct tgcagggctt ttgtatatca tcgcgctgat 769861 gtatgtgttt cccctttatg tgcattacca gctcccgctt cgcaaatata ttccgcaggc 769921 actgctgttt ggcgccatga gaccgctgac aactggctgt atgctgatcg ggtgcggatt 769981 tgtcctttat ttgctgtata cgcttcctgg cctgatccca ttttacggcc cgtgtttatt 770041 tgggcttgtg ttgatgtttt ttgctcttag gggatttcaa aagacggagg cccagcacca 770101 tcaagccggg taacaaaaaa atgacaaata agcaaaaaag tgcagtgtcc gaaataggca 770161 gatgcaaaaa agtgaaattg aagacagctc acaaagcgca taaaatccaa tttaagtaag 770221 cgcttacaga taaatgagaa ggagctgtct gatgattaga cgaaggaaac gcatgtttac 770281 cgctgttacg ttgctggtct tgttggtgat gggaacctct gtatgtcctg tgaaagctga 770341 aggggcagcg cggcagatgg aagcgctgaa ccgggggctt gtagcggtca agacggacgg 770401 gggcattttt gtcagctggc ggtttcttgg aaccgaaaac gcatctgttt tgttcaatgt 770461 gtacagagac gggcaaaaac tgaatgctgc gcctgtcaaa acaacgaact atgtggataa 770521 aaacggttcg gcgggctcaa cgtatacggt tcgggctgtt gtaaacggta ccgaacagcc 770581 ggcttctgaa aaagcctccg tatgggcgca gccgtatcat tccgtcccgc tggataaacc 770641 ggctggcggc acgacgccaa agggtgaatc ttacacgtac agcgctaatg acgcaagtgt 770701 tggcgatgtg gatggtgacg ggcaatacga gctgatcctg aaatgggacc cgtccaactc 770761 aaaagacaat tcacaggatg gctatacggg tgacgtgctg attgacgcgt ataaactgga 770821 cggcacaaag ttatggcgga tcaatctcgg caaaaacatc agagcgggcg cgcactacac 770881 ccagtttatg gtgtatgacc ttgatggtga cggaaaagca gaagtggcaa tgaaaacggc 770941 agacgggaca aaagacggca cgggcaaagt aattggaaat gccaatgcag attacagaaa 771001 tgaacagggg cgtgtgcttt caggccctga atatctcact gtgtttcaag gttcaaccgg 771061 gaaagagctt gtcaccgcaa attttgaacc ggcgcgcggc aatgtgtcgg attggggaga 771121 cagctacggc aaccgtgttg accgttttct cgccggcatt gcctaccttg atggacagcg 771181 gccgagcctg atcatgacca gagggtatta cgctaaaacc atgctagttg cctataactt 771241 cagggacgga aagctgtcaa agctttggac gctggactcc tcaaagtcag gaaatgaagc 771301 gtttgccgga caggggaatc acaacctgag catcgcggac gttgacgggg atggaaaaga 771361 tgagattatt ttcggctcaa tggctgttga tcatgacggg aaaggcatgt actcgaccgg 771421 cttaggccat ggggatgccc tccatacagg agatcttgat ccgggccggc cggggcttga 771481 ggtgtttcaa gttcatgagg acaaaaatgc aaaatacggc ttatctttcc gggatgctgc 771541 aactggaaaa atcctttggg gcgtttatgc cggcaaggat gtaggccggg gaatggctgc 771601 tgatattgac ccgcgttatc cgggacagga ggtgtgggca aacggttctc tctactcagc 771661 gaaaggggtc aaaatcggaa gcggggttcc gtcctcgacc aacttcggca tctggtggga 771721 cggcgatctg ctccgggaac agctggacag caaccgaatt gataagtggg attatcaaaa 771781 cggcgtatcg aaaaatatgc tgactgcatc aggcgcagcg gctaacaacg gcacaaaagc 771841 aacaccaacg cttcaggctg atctgctcgg tgactggcgc gaggaagtgg tgtggagaac 771901 ggaggacagc agtgctctgc gcatttacac gacgaccatt ccgactgagc acaggctgta 771961 tacgctgatg cacgatccgg tgtaccggct tggcatcgcc tggcaaaata tcgcctataa 772021 ccagccgccg cacacaagct tctttttagg agacggcatg gcggaacagc caaaaccaaa 772081 tatgtatacg ccttaactga aagggggaag gaacgggctg cgcgcagccc gttcccatca 772141 aatgaaacca aaaaagaggc aaatggaata cctgaccaga ggtttgattg cggtacagac 772201 agaacagggc gtgtttgtca gctggcgttt tctcggcacg gatcatgaga cgacggcttt 772261 tcacctttat cgggatggaa agcggatcac ccgcgatcca atcgctgaaa gcactaattt 772321 tctcgatcaa aacggaacgg ctgactctgt ttatcaagtg gcggctgtca ataaaggacg 772381 ggaagaaaag ctttccaaga aagctcgtgt ttggcaggaa aatgtcctgg aggttcctct 772441 tgccaaaccg gaaggcggtg tgacgccgga cggaaagccg tacacttaca gcgccaatga 772501 tgccagtgtc ggggatatag acggggatgg agaatatgaa atgatcctga agtgggaccc 772561 gtccaattca aaagacaacg ctcatgacgg ttataccggg gaggtgctca tagatgccta 772621 taaactggac ggcacctttt tgtggcgcat caacctcggc agaaacatca gagcgggtgc 772681 tcattacacg caatttatgg tgtatgacct tgacggtgac ggaaaagcag aaatcgccat 772741 gaaaacagct gacggcacaa cagacgggaa aggacatatc atcggtgatg agcaggccga 772801 ttttagaaac gaacagggca gaattttgtc cggtccggaa tatttgaccg tgtttaaagg 772861 agaaaccggt gaggcgctca cgaccgtgga atatgaaccg ccccgcggca agctggagga 772921 ttggggagac ggctatggaa accggatgga ccgttttctc gccgggaccg cttatttgga 772981 tggggagcgg ccgagccttg ttatggcgcg cggctactat acgagaaccg tgctcgtggc 773041 atacgatttc agaaacggaa ggctcaaaaa acgatgggta tttgactcca accagccggg 773101 acatgaagca tacgcaggac aggggaacca cagcttgagc gtggcggacg tcgacggaga 773161 cggaaaggat gaaatcatat acggcgcaat ggctgtcgat catgacggaa ccggcctgta 773221 ctcaacgggc ctcgggcacg gagacgcgat gcatgtaggg gatctggacc cgtcacgaaa 773281 agggcttgaa gtgttccagg tgcatgagga cgccacgaag ccgtacggac tgtcgctgcg 773341 agatgccgga accggtgaga tattatgggg cgtccatgct ggaactgacg ttggccgggg 773401 catggcggct catattgatc caagctacaa aggatcgctc gtctggggaa ttgatccgcc 773461 gggcaatgat ggcatgtcgt acgggctttt cacgagcaaa ggcgaaaaaa tcagcgacaa 773521 agcgccctct tcagccaatt tcgccatctg gtgggacggt gatttggtca gagaactgct 773581 tgatcatgac tgggacggaa cgatcggcag gccaaagatt gaaaaatggg atgctgaaaa 773641 cggctgtctg aagacgatat ttcagccggc cggcgtgttg tccaacaacg gcacgaaagg 773701 aaacccggtt cttcaggcca acctgttcgg agactggcgg gaagaagtga tatggagaac 773761 ggaagacagc agcgcgctcc gtatctatac aacaacacat ctcacccgcc actgctttta 773821 cacgctgatg catgatccgg tttacaggct cggcatcgcc tggcagaata ccgcctacaa 773881 ccagccgccg cacacgagct tttacctcgg aacgggaatg aaaaaaccgc cgaagcccgc 773941 cctgtacata gcgggaagca aagcggaggc gccgctgtag gaggactaag ggataagacg 774001 caaaggctga acgctacgcc aagatgatta gagaactggc aggacgaacc aatgctcaag 774061 cgctgtacgc accggttttt tcaagggaag agctatccgt gatggaagct gtataaaaaa 774121 cgaggaggaa tgaaaaaatg gcaaatcata tttatcttgc cggcgattcg actgttcaaa 774181 cgtatggaga cagcacaaat caagggggct gggggcagtt tctcggctcg catctgccgg 774241 agcatattca agtgatcaac agagcgatcg ggggaagaag ctcgaaaaca tttgtggaag 774301 agggcaggct tcaggcaatc ctcgatgtga ttgagccgga tgattggctg ttcgtgcaga 774361 tgggccataa tgacgcgtca aaaaataagc cggagcgcta caccgagccc tatactactt 774421 ataaacaata tttaaagcag tatatcgcag gcgcgcggga aaaaggcgcc catccgcttc 774481 tcattacccc cgtagcccgc tttcattacg aaaacggcgt gtttttgaac gattttcctg 774541 attactgcat tgccatgaag cagacggccg ctgaggagaa tgtccagctc attgatctga 774601 tggagaaaag tctcgctttc tttactgaga agggcgagga aaaagtgtac acctatttta 774661 tgatttcaga agggattaac gattacacgc attttacaaa aaaaggcgca aatgaaatgg 774721 cgaaacttgt ggcaaaaggc ataaaggagc tcggcctgcc attgacagaa tcgatcatca 774781 aagaaaggtg aaaatgtgat gagaaaactg tatcatggcg cttgctatta tccggaatta 774841 tgggatgaag agacgattca gcaggacatt gacatcatgc gtgaagttgg cgtaaatgtt 774901 gtgcggatcg gcgaatttgc ctggtcagtc atggaacctg aagaaggaaa aattgacgtc 774961 ggttttttca aagaaatcat cgcccggctg tatgatagcg ggatcgaaac gattatgtgc 775021 acgccgacgc ctaccccgcc gatttggttc tcacatggcc ggcccgaacg catgcatgcc 775081 aatgaaaaaa gagagatcat ggggcatggc tcccgtcagc atgcctgtac gaacaacccg 775141 tatttccgaa aaaaagccgc catcatcacc acagccatcg ccaaggagct tggccggctc 775201 ccggggctga tcggatggca gctagacaat gagtttaaat gccatgttgc agaatgcatg 775261 tgtgagacat gcttgcgcct atggcatgac tggctcaaaa atcgctacgg ggtaattgag 775321 cgcttgaatg aagcttgggg aaccgatgtg tggagcgaga cctatcagac gtttgagcaa 775381 gtcccgcagc cgggaccggc cccgtttctg catcatgcct ctctacgcac tatgtatcag 775441 ctgttttcga tggagatgat cgcttcgttt gcggatgaac aggccaaaat catccgctgc 775501 tattcagatg cgccgatcac gcataacgga tcagtcatgt tcagcgtgga caatgagcga 775561 atgtttcaga atctcgattt tgcctcctat gacacgtacg cttcgcagga aaacgcctct 775621 gcctttttat tgaactgtga tttatggaga aatctgaaac aagggcgccc gttttggatt 775681 ttggaaacga gtccgtcgta tgccgcctcg cttgaaagct ccgcttaccc gcacgcagac 775741 gggtatttgc aggccgaagc cgtatcgtcc tacgccttag ggagccaggg gttttgctac 775801 tggctatggc gacagcagcg ttcaggcagc gagatttccc acggttcggt tctcagtgcc 775861 tggggcgaac ccaccatcgg ctatcaaaat gtgctggcgg ttgagcgggc aagaaaggaa 775921 atcgagccta ttattctatc gactgaaccc gttcaagccg aggcggcgat gacttactct 775981 gacagagcaa aagcatttat taaaactgag cctcaccggg gactccggca tcgttcgctt 776041 gtgacgcatt tttatgaacg tattctcaac acggggattc accgtgacct tattccggaa 776101 ggcgctccac tggacggcta tcgcttgctg tttacgccat ttgtgccgta tttgtcttct 776161 gaatttatca aaaaagcttc ggcattcgct gaagcgggcg gcatctggat caccgggccg 776221 ctgacaggag gacgcacatg cgagcatacc attcataccg attgcggact tggcgaactt 776281 gagaaaacgt cagggatcaa aacacttttt acctttccga tgaatgagaa cgtgaataca 776341 ggaaaagcgt ttggcatcac ggcgccgctc ggactgtgga gcgcggtgtt tgacacagag 776401 agcggaaaca cccttggcac ggttgaagca ggaccggggg cgggccatgc ttttctgacg 776461 gaacggaatt acggcgaggg gaaaattgtc atgctgggct cgcttccatc cgggaaagaa 776521 ggggatgcga tgctggaagc gctcgtcagg cattatgcgg aggaagctgt tatttccagc 776581 cggtcggatg tgacacccgg cacgatcgtt gccccgcgta taggcgaaaa cggccttgtg 776641 tggatcgttg tgaatatgga tggaaaaggc gggagcgtga cattgccgga atcgggaacg 776701 gatttgttga cgcaccgctt ggaaaaggcg gggagactgg cggtcggacc gcatgaatac 776761 cgtgtgattc aatttgacaa tcacagctga ttctttgtat cgaatcagct tttttctatg 776821 gagggagaga cagatgaaaa agatcaaatg gttatcagga cagccaaagg tgacaagcgg 776881 cgtgacgtgg ggcatgccat ggaaaaaagg agaattaaaa aaaggagacc gtctggcgct 776941 tatgaatgaa aacgcggaaa cgcgatatgt gcaaagcgaa ccgtcggcct attggccgga 777001 cgggagcatc aagtggacga agcacgcggc ggtgtttggc ggtcaggaaa accaaagctt 777061 tacagtgcac aaaagagaag tgccgcagcc aactgaatcg ctcagcattc ttgagacaga 777121 gcatgatatc caagtggata caggagcact cgtttgtacc attcataaaa caggatctga 777181 tttcattcaa tcattgcaga tcaatggaaa gccgatcgcc gcaggcggga ggctcgttgc 777241 gataagagaa acgagaaaag agtcagcggc gaaaatggtt cttttgcatg aaaggtctgt 777301 cagctttatc aaacgggcgg cgattgagca gagtggtcct gtcaaagcag tagtcaaaat 777361 cgagggagtg catgtgcttc ataaaacgta tgaggaatgg ctgccgtttg tcatccgatt 777421 aacgttttat gccgggctgt ctgagatcgg ccttgtgcac acgcagctga ttgacaggag 777481 cggtaaacta gaattcgtta aggggctcgg catcgaattc gacctttttt tggagggaga 777541 gccgtacaac cgccatttcc gctttgcggg agagaaaggg atgtataaag aacccgccca 777601 gctgtttggc acacgtaaat tcaatgaacg atatccgctt tatgaaaaac aaatcaatgg 777661 cgaaatgctg tctccagatg aagagcataa ggaatggttt gcacatggca cacagaatgc 777721 ggtttgggac gatgtcaaga tcgtgcaaga ttccagcgat cattacagcc tgtcaaaacg 777781 gaccggaaaa gattatgcgt gggttggaat gctgcatggc agccgggcga aggggctctg 777841 ctatgcgggc ggaaaaaatg gcggtgtggc tctcggcctg cggtatttct ttgagaaata 777901 tccttcagca ctggaaatca caggtcttgc cggcagccgc cccaaaatga ctatctggct 777961 ttggcctccg gacggcgaag cgatggattt gcggcattat acaggaaaca ctcacgtggc 778021 cagcgcgtat gaaggctttg atgaaatgcg ctctgatccg acaggcattg cgaacacaaa 778081 tgaaataagc ctggcgtgct tttcgcacat gccgtctgac gaagtcctca atgcgctggc 778141 tgacaaatgg caggcgcccc cgctcattgt atgcgagccg gacgtctatt acgaatcaaa 778201 agcactcggg gtatggagca tcattgacac atcccatccg ctcaaaaaag agctggaaga 778261 acagcttgat gcggcctttc tgttttataa aaaggaagta gagcaacgca gatggtacgg 778321 tttttggcat tatggcgatg tcatgcatac gtatgacccg atccggcata tgtggcggta 778381 cgatctcggc ggatacgcat ggcaaaacaa tgagctcgtt ccgaccctat ggctgtggca 778441 ggcgtttttc cgctcaggca gagaggatat cttccgaatg gcagaagcca tgacccgcca 778501 tacgagtgaa acggacagct ttcacctcgg tgaatatgcc gggcttggct cacggcataa 778561 tgttgtgcac tggggatgcg gctgcaagga agcgagaatc agcatggccg ggcttcataa 778621 attctattat tatctgacgg gtgatgaccg gacgggagat cttttgacag aagtgaagga 778681 tgccgattat gcccttgtca aaaccgatcc gatgcgcgct ttttacgaga aaggcaagca 778741 cccgactcac gccagaacgg gaccggactg ggcggcgttt tgctcgaact ggctggcgga 778801 atgggagcgg accgaaaatt cggaatatct caaaaaaatc gaaacgggaa tcaactgtct 778861 gaagcggctg ccgctccgct tattatctgg cccgacattt gaatatgatc cggcgacctc 778921 gatgcttcat catatgggag acggcattgc gggcggatat catatgatca ttgccttcgg 778981 cgcgccgcaa gtgtggatgg agctggctga gcttcttgat gactgggaat gggaggatat 779041 gctgagtgaa ttcggcgaat tttacacact cagtgatgag gaaaaacgaa aaaaaagcgg 779101 aggcgctctt catgacgggc attttcactg gccgatgttc gccgccggta tgacagccta 779161 cgccgcaaga aaaaagcaag atcctcatct cgccgccaaa gcgtggaatc ttttgctaga 779221 agataagctc agccatacgc cgcttccgat caaaccggag cgcatcgaga catggacgca 779281 gctagaggag cttccatggg tgacaacgaa cactgtctct caatggtgtt taaatgtcat 779341 agcggcgctg gaactgatcg gagattccct tccggcaaaa aaagaaacat cgggcaaaaa 779401 aggataacag ccggaatttc ataggagaaa tggtgcaaaa aatgaagatt gcaagaattt 779461 atgtaagcgc tttatattga gaggggcaaa ggggaaatgc aaattgaaaa aagggggact 779521 tacgcaacat gaaaataaga atgcgaaaaa aatggatggc cttgccgctt gctgccatga 779581 tgatcgccgg atgcagccat tcggaaacat ccaattcagc aagcggttcg aaagatacga 779641 tcaaaattat ggcgccgctc ttatcgccgg aaagcccaag tgataagagc ccttcattaa 779701 aagcgctcga aaaatacaca ggcaaagaga ttaaggtcac atgggtgcct gattcatcct 779761 acaacgacaa attcaacatc gtcatggctt caggagagat gcctcacgcg attgtcatta 779821 aagataagtc agccggcttt atcaaatctg tcaaagcagg ggcgttttgg gagctgtctc 779881 cttatttaaa agactacaag aatttaagcc aggcagatga aaagattttg aagaacagct 779941 cggtgaacgg cgaggtgtac ggaatctaca gaacgaggga tctgatcagg gcgtgtatga 780001 tcatcagaac cgactggctg aaaaatgtcg gtctggatat gccggaaacg cttgatgatt 780061 tctatgaagt gctgaaagcc tttaaggaaa aagatcctga cggaaacggc aaggatgata 780121 cgtacggcat ggtcgtgccg aaatggatgg gactcggcaa cggaagccca tgggatgttc 780181 tgcaaatctg gttcggcgct ccgaaccgct acggtgttga aaacggaaag ctgattccag 780241 attttacaac gaaggaatac atggatgcgc tcacgttttt taaaaagctc tatgatgagg 780301 gcttgatcaa taaggacttt gctgtcatgg attctgcgaa gtggaatgat ccggttgtaa 780361 aaggaaaagc gggtgtcatc gttgatacag gctcaagagc gtctcaaatc caaagcgcga 780421 tggaggaggc ggatgagtcg aacaaggata tcattgatat cgtcggctcg cttgagggac 780481 cgaatggcaa gcgcaccttc ccgacatctg gttattcagg catgatcacg ataccaaaat 780541 caagcgtcaa aaccgaaaaa gagctgaaag aggtgctgtc cttcctcgat aagatgaatg 780601 ataaggaagc gcagattctc acgaacaacg gagtgaaggg ccgcaattac gagctcaagg 780661 acggcgtatt cacctcactt gaaaaaaaca ataaatctct cctgtatgag catgaaggct 780721 tggcacagtt cagcatgtcg attccgaaaa gcgagtatta catcgaagac cagaaaacca 780781 agctcttcca gcatcgcaag gacatcataa ccgaaggaga aaaaatagcc gtctttaacc 780841 ctgctgagtc gcttgtatct gatgtctata cccaaaaagg agcccagctt gacaacatca 780901 tcctcgacgc gagaacacaa tttatcattg gagaaattga tgaaaaaggg ttcgatgatg 780961 cggtggagct ttggaaaaaa agcggcggca atgaactgat gaaggacttg aacaaattgt 781021 accaatcgtc aaaataaacc gatgcgcctg cctttcggcg ggcgccccgg tatcacgaaa 781081 ggagaacaga tatggaaaca gtgccgaaga agagagatgc acctgttctc accgctggaa 781141 aaggcatcag ctggatggct gcgctcaaac gggacaaatg gctttatctt cttcttattc 781201 ccggtctgct ttatttcttg attttcaaat acttgccgat gtggggtgtg ctgatcgctt 781261 ttaaagacta ttcgccatat ctcggcttct ggaaaagcga atgggtcggc tttgattatt 781321 tcaaagactt ttttatgaat ccggattttt tccggctgct gcgcaacacc ctcatgctgg 781381 cgagtctgga tcttttgttt gcctttcccg cgcctctcat tttggctctg cttttgaatg 781441 aggtaagaaa ggccgtgtat aaaagatgta tccaaacctt tatttacgta ccccattttg 781501 tatcatggac aattgtggtc agcatcacct tcgttttctt tactgtcgat acaggtgtga 781561 tcaacaaatt gattatgagc ctgacaggtg agcagatttc tttcttgtcg gatgcagact 781621 ggttccggcc aatgattgtg atgcaaagca tttggaagga gacaggctgg ggaacgattc 781681 tatttttggc agcgcttgct acggttgatc aagagcagta tgaagcggcc atcatggacg 781741 gagcggggcg gttcaggaga atgtggcata ttacgctgcc ggcgattaga agcaccatta 781801 tcgttttgtt gattttaaga atcggcagct ttttgaatct tggctttgaa caggtgtatt 781861 tgatgacgaa ctcactcaac cgcagtgtgg ctgacatctt cgacacgtat gtgtacatga 781921 tggggattac ccaaggggcg tatagctaca gcacggcggt cggtttgttt aaatcagttg 781981 tcgggattat cttgattttt ggcgccaatt acattgcgaa aaagtttgat caggaaggat 782041 tgttttagag gagggagagg tatggctgaa attcacacga tgcacaacac caaagccgga 782101 cgggtgtttg acgtctgcaa cattctgttt ctcggcggtg tcggcgcgat taccattttg 782161 ccgtttttat atattatcgc cggttccttt gcgacagaag cggaactcgc ccagcggagc 782221 ttctttattt tcccgaaaac ctttacactt gatgcttaca agtatgtgtt ttcgacaccg 782281 acgttccttc gaagcatggg cgtgtccatc ttcatcacgg tggttgggac ggctgtacag 782341 ctgtttttta ccttcacgat ggcgtatccg ctggcgaaac ggcatgtgaa gggacggaat 782401 ctgctgttga atctggtgat tttctccatg ctgttttcag gcggcatgat tccgacgtac 782461 cttgtcgtaa aatcacttgg ccttttggat acgtattggg cattgattct gccgatggcg 782521 attaatccgt tcaaccttat tattatcaaa aacttctttc agcagctgcc gcgcgagctg 782581 gaggaatcag caaaaattga cggctgttcc gaaatcggcg tcttctggcg gatcgccctg 782641 cctctgtcaa agccagttat tgcgaccttt gcgctgtttt atgcggtcgg gatttggaat 782701 gatttcttcc acgctctctt atatatcaat gacagtgcaa aatggccgct gcaaatggtg 782761 cttcgccaag tcacaatttt atcggattta acggcgacca atggtgatac gatgcaaaat 782821 gcagttccgc cggagcaggg aattaaactc gctgtcattg tcattgcgac gctgccgatt 782881 ttggcggtct atccattttt acaaaaacac tttgcaaaag gaatgctgat cggttcggtg 782941 aaaggctgag aaagggagtg tttcatatca gtacattaga tcagattaag attgcctata 783001 tcggcggggg gtcccaaggc tgggccagaa gcctgatgag tgatttgtcg attgatgaac 783061 ggatgtcagg cacggtggcg ctctatgatc ttgattttga agccgctcag aaaaatgaag 783121 tgatcggcaa tcacagcggg aacggcagat ggagatatga ggctgtttct actttgaaaa 783181 aggcgttatc agccgcggat atcgtcatta tttccatttt gccgggatca ctggatgata 783241 tggaagtcga tgtgcacttg cctgagcgct gcggtattta tcagtctgta ggtgatactg 783301 tcgggcctgg agggatcatc aggggcttgc gtgctgtgcc gatatttgcg gaaattgccc 783361 gggcaataag agactacgca cctgaatcat gggtcattaa ttatacaaac ccgatgtctg 783421 tctgtacaag agtgctgtat aaagtgtttc ccggcatcaa agcgattggc tgctgccacg 783481 aggtattcgg gacgcaaaag ctattggcgg aaatggtcac ggaaaggctg gggattgagg 783541 tgccgcggcg tgaggatatc cgcgttaatg tgctcggcat taaccatttt acatggatca 783601 caaaagcctc ttaccgccat attgacctgt tgcctatatt ccgtgaattc agcgcgcact 783661 atggggaatc aggatatgag ctggaggggg aatgctggag ggacagcgtc ttttgttcgg 783721 cacaccgtgt tgcgtttgat ttatttgaaa cgtatggcgc catccctgct gcgggtgaca 783781 ggcatctggc agagtttctt cccggcccat acctcaaaca gcctgaagta tggaaatttc 783841 atctcacacc tatatcattc agaaaacaag acagagctga gaaacgacaa gaaacagaac 783901 ggttgatcgt gcaacaacgg ggcgttgctg agaaagcttc gggagaagaa ggcgtgaaca 783961 tcatagcggc tcttctcgga ttgggtgaac tcgtcacaaa tgtaaatatg ccgaatcaag 784021 gccaggtctt aaaccttcct atacaagcca ttgtcgaaac aaacgcattc atcacaagga 784081 accgtgtcca gccgattttg tccggagcgc ttccgaaagg tgtggaaatg ctggcggcta 784141 ggcatatatc caatcaggag gcagtggcgg acgcaggttt aacaaaggat actggcctcg 784201 cgtttcaagc cttcctcaat gacccgcttg tccagattga ccgcagtgat gcagagcagc 784261 ttttcaatga catgctccaa tgcatcatgc aaagctgagc ttgccgatta gctctttccg 784321 gtttagaaag gaaagcattg accatactga tagtataatc aagaagtagg tgctatcaat 784381 atgggaaatt atttaagtgt tgcggtagaa ctggtctgcg gtttaggcat tttatttatc 784441 atcttaaagc ttctcgggaa aacccaattt tctcaaatta cgccgtttga ctttatttct 784501 gctttaattt taggtgaatt ggtcggaaat gccgtctacg atcatgaaat caaaatcaaa 784561 gaaattattt ttgcttcgct attgtggggc gtgctgattt atattattga atttatcacg 784621 caaaaaatga aatcatcgcg aaagttcttg gagggcgagc cgaatatcgt catccgcaaa 784681 ggggagcttc aatataaagt aatgaagaaa aataagatag acattaacca gctgcaaagc 784741 ctattgaggc aagctgggag cttttcgatc caagaagtag aatatgcgat tcttgaaaca 784801 aacgggatgg tcagcgtgct tccaaaatca gactttgaca aaccgacaaa taaggatttg 784861 cagattcctt cgaagtccgt ttctctgccg atcacgttaa tcatagatgg agagattgtg 784921 cgggataatt tgaaggaagc aggtgtggat gaacagtggc tgaaacaaga attgaaaaag 784981 aagaacattg ataagacaga ggacgtgtta tttgcagaat ggcataaaaa taagccgctg 785041 tatactgtaa cgtacgaaca aagcagatca acatgactct tagaaaaaag cttgcagcaa 785101 ggcgcaagct ttttattgat tgtatgtccc ttgtttgaca gcacgtacat ggtacatgct 785161 cacttcagtg ctgatcagat agtcaggctt tggtttgcct ttgtttgctt tatggccggc 785221 gatatgcgca tcgctttttt cccattgctt ccagtgatcc tctgattccc agcgaatcat 785281 gacaacaact tcttcatcac cgcggcgcac atttttctca agcactgtca catcaattaa 785341 accttcttgt ttttcaatga ttccttcagc gctgaaacgt tctatgactt tatctgcaaa 785401 gccttcttta accgtcattt ttctcaactg tacaaacatt tgtctcactc caatcattct 785461 cacatatgaa taattgtaaa tgaaattcat tctcaatgtc aaagaaagcg cagggcggaa 785521 tcgaaccgcc gtgcgcaaca gtttattctt ttaataaaaa cacatttccg tcttcgtcct 785581 taaattgaac gaaggtgccc cactccattt gattgggctc accgagaaat tctacaccgt 785641 ttgtcttcat tttctcgtat gtaccaaaga tgtcttcgca ttcaaacaca atagaagcct 785701 tcatttgctc tgagcctttc atcatggctt tcgggtaaat gactaaacga gtctcggctc 785761 cttttggcgc aacctccagc cagcttgctt caggtcccat tgggtgatcc gctgcaatat 785821 caaagcctac cttctctgtc caaaattgct tcgctttctg ctggtcctcg acatatacag 785881 caacagtgcc aatttgtttg atcataggga aacctccaag ttgaaaagat aataatacta 785941 taacctgttt acggccgaag taacataaaa aaatcagccg ggaaaccggc tgattattaa 786001 aatgagcagc ttacaacatc gatgtgattt gtgtctaagg cgaaataaac ccagcggcgc 786061 cgtgaggaat cccaataaaa gccgccgacg gatcttctgc caaggatgat cgggtaaaac 786121 caaaatgagc ggccattggt taaccagaca taggtaaatc ggaaaaggca aggacgaatg 786181 gtgattggtt caactaacaa aacggctcct tgagaaccct gcggttttgg gggtttcgct 786241 ggtatttggg aaggaggagg tccctgcggc gcaccgccga agcctgggct ggcaccgctg 786301 ccaataccag ggccggagcc gccgccaaag cctggaacag caccaccgcc aatgccagga 786361 ccggagccgc cgccagagcc cggaacagcg ccgctgccaa tgccaggcca tggatatcgg 786421 tattcatatt caaaagcagg ccaaggctca taaaaatgcc ccgcaaacat ataaggatca 786481 acataataca tgtgataacg tcctttctca ttgtaaactg tacattgcag tttatgcggg 786541 cggactctta ttggtgcatt cgcctaagga tatgaagctg gaatgctctc agagagcaga 786601 atcatttgat ttttctctag tcttattcac aattccgatt tatcatttta taatgaaagt 786661 gcttctatta cgaaaaagga gacagaccgt gaatatcgat caattattat atcaatatat 786721 catagacaac actgcggata ttactgagaa atggttcagt ttgcgttgcc agctaaaagg 786781 cgagctatat tccgccagcc atttaagtga agaaacgaaa acacttttaa ccgagcagca 786841 tacatttacc aatataacaa tcgcaagcgc atttctggag gatcaaaccg attttcaaga 786901 aaacatgaca aaatgggcgc aaaacgttgc gaaaaacagg gtagagcagg atgttcaagt 786961 gcatgaggtc gtagaagcca tatccaattc aagaatctca ttctgggacg cagtcgccac 787021 atttataaaa gagaatcagg agattgtgac aaatgaggat gcagaccgat ggaaccgcat 787081 tgtgaatcag tcgttcgata agctgattat tgaattctcc gagcagtacc aaaaattcat 787141 gctgatgagg cttacatctc agcaggaact gatctcagag cttggctgcc cggtcatttc 787201 cattgccgat ggaatcggga tattgccgct tatcggctcc attgatacaa aacggcacag 787261 gtcattttag aaacagtgcc ggtccgctgt gtcgagagaa aaatcacaag cctcgtcgtt 787321 gatctttcgg gtgttccgat tgtggatacc atggtggctc agcaattgta caacctgtct 787381 aaaacacttt tcttattagg cgtcaaagcc gtattttcag gaattcgccc ggatgtggcc 787441 caaacatcga ttcaattggg gcttgatttt agtgaatatg aaacgtacgg cacgctgaag 787501 caggcattag aaaacatggg tgtccgctgt attgttgagg aattggaaga aaacaaatag 787561 gaagtttcca ggcatatgat tgtccgtcac cgggtgatca tatgcctttt tgatttgaac 787621 agaaatcacc attgatttat cgaaaaaaac ataatattat aattcttata agaatactgt 787681 gaattaaaac ctattcaaca ggggggaagg tcttttggtt tctaaatcaa cgattgatcc 787741 ggaagtgatt gaaaaaatca tcagctcgct ggaaacactc gatttcggca cggttcagat 787801 tacggttcat gattctcaga ttacccaaat tgagaaaata gaaaagcacc gtttttcgct 787861 gaaaaggaaa gaatcaaaat gataatgtaa agggcgtttg ttttcattaa attctcctta 787921 aaacatatac atatttcatc caatttttat ataatagacc tttaagatca ttttttagga 787981 ggatttttga catgcaagct acggttcacg agagtaagca atcgatcatg caacgcattt 788041 tgacagtctt tgtcttcaca ttgctgatcg cgactgtcgg cctttttatc ggccaatttg 788101 ttcctgtcgc tttgatgctg ccgctttcta ttcttgaagt ggcgatgatt attctggcct 788161 tctggatgcg cagaagaaaa gcggtcgggt atgcgtttgt atatacattc gcgttcgttt 788221 ccggcattac cttatttccg atcgtcagcc attacgcttc catcgccggc gcctatgtcg 788281 tgctcgaagc ctttggctct acatttgtca tttttgccgt cttgggcaca atcggcgcaa 788341 aaatgaagaa ggatttatcc ttcctgtggt cgtttctgct ggttgcggtg ctcgcactcg 788401 cagtggtagg gattttcaac attttcagcc cgttaaactc agcggcgatg atggcgtatt 788461 ccgtgatcgg aaccatcgtc ttttcccttt acattttgta tgatttgaac caaatcaagc 788521 accgccacat tacggaagac ttgattccgg ttatggcgtt atcgctgtac ctagacttta 788581 tcaacttgtt catcaacctg ctccgcttct tcggcatttt gagcagtgat gattaatgaa 788641 aaagcgtctg tcattggata ggcgcttttt gccatacatc aaaaaggcag gtggagtatt 788701 ggtgaaaaaa caaatgggcg catatgtatc tctggcagca gctatggcga tcgtcggcag 788761 ttctgtcgtt gtcggcaagc tgatggtcga acggattccg gtctttcttt cctcaggatt 788821 gcgttttttg atcgcttctg tcgtattgct catgctgctg ttttgcattg aaaaagggtt 788881 tccggctttg acgaaaaaag atgtgttcgt attactggtg caatcattca caggcgtgtt 788941 tttgttcagt atttgcctgc tgtatggggt tcaatatacg acgggaacgg aaagcggcat 789001 tttgacaagc acaaccccca tgttgatcgg tattttatcc tttttcctgc tgagagaaaa 789061 aattgagaaa aagacgctga tcggcatttt gctggcggtt tgcggcgtaa tggcgattaa 789121 tttgtttgga gccgggagcc aagacgggac gccgcacgcc ttattcggga acatgctgat 789181 cattgctgca gtcattggcg aagcgttgtt tacattgatg gccaagctgc tatccccgca 789241 tatttcggca ctggcgattt cgaccttcgt atcgctcttc ggcttcctgt tttttctccc 789301 gtttgctttg tttgaggcct cttcatttga ttacagcgtg ccgactgttt tggattggtc 789361 gtatgtgctg tattacgcgc tttttgtcac tgttttggcg ttttacttat ggtatagcgg 789421 ggtgacgaag gtgccggcgg gtgtatcggg cattttcaca tccgttcttc cggtctcagc 789481 tgtcattttg tcaggcgtga tattgaagga gccatttgag tttgtgcatt tcatcggcat 789541 tgcatgtgtc atcggcggca tatttgttac ggtcataaag aaaaaacagc cggatgcgta 789601 tccggctgca gaagaaaaga cgctatagcc tgtccggatc ggacgggttt tttagtcttt 789661 aaacacgctc agcctttcaa aaagatcacc aagcatcttc acgaacatgt ctttttcctc 789721 gtcgctgtag ttttccatga cagcggatat tttgctgaaa tggccgggca gaaattgctc 789781 caggcgtgct ttgccttctg ttgtcagttc aatgctgatt tttcgtttat cctctgtgtg 789841 atgcctgcgg ctgacaaaac cgtctctcgc cagcccgtct agcaggcctg taattgttgc 789901 tttcgtgaca tttgaccgct tggcaagctc tgtcggactt aacctatgat ccttggcatc 789961 aaagagcagc atcaggattt tgaattttcc ttctgaaagc cctcggccag caaagtaatg 790021 ctccatcaca tgattcattt tttttgaaat atcaaaaaga gataaaaaca attcaagaga 790081 gccggcgtca atattggcat acgtttcggc gtgctctgtt atatgcttat atttcggtaa 790141 atgttttaat tccatcgcaa ttagctcccg tacattcgtt gtgacacgat tataaaggag 790201 ggaaaaccat aacgcaactt ggcttggaga tgattgacag cttttcttgg gacatagtaa 790261 ggtaatatag ttaggcgcct aactaataca tatagagctg aaaaggtggt tattgatatg 790321 aaacatatgt taatagcagg aggcggaatc ggcggcttgt cagcggccat ttctctccgt 790381 aaggcagggt tttccgtcac cttatgtgaa gcggcttcag aaaatcgaaa aacaggtgcg 790441 gggattcttc agccgcaaaa cgcactggcg gtgttgaaag aactgggcgt attcgaagat 790501 tgctgtaagc acggctttca aacagaatgg tttaaaacgt ttgatgaaca ggggaatttg 790561 ctgtttcaag tcagtgaatc ctttttagac gattcacttc cgggacgcaa taatatcctg 790621 cgcaaaacgt taaatgacat tctcatgaag catgccgagg cagtgggtgt agacatcaag 790681 tgggggaaaa aggttgtcgc ctatgaagaa actgctgaat cggtcactgc cttatgtgaa 790741 gatggagaaa agatgcaggc tgacattctg gcgggctttg acggcattca ctccgttgtt 790801 cgtgataaga tgctgcaaaa ggaaacggaa aaagagcatc tcggcatggg agcgtggcgc 790861 ttttatatcg aacttcctga ttacacattc gaggacgcaa cattcatgta tagaagcgga 790921 gacacacaaa tcggggtggt gccattggca caacacgctg gctatgtctt cgtcctccag 790981 ccttgcacga gcgattactg ggatgaggaa gatacccggt ttgatagagt aaaagagatt 791041 ctttctggtt ttcgggggct ggattttgtc acaaagcaca tgtcaaaaca gcatcctgtc 791101 atctttaaca aactggagca ggtcgccgtg caggagccat ggcataaagg ccgcgtcatc 791161 atcggaggag acgccgccca cgccggtgcg ccaaccctgg cacaaggagc ggcaatggcg 791221 atcgaggatg ccatcgtcct cgccgaagaa ctccaaaacc acgccgacca cgaaacagca 791281 ttacaggcgt actataaaag aagagcccca cgagcgctca aagtccagaa cctatcatct 791341 gaaatcgtcc gccgcaggct gaaaggagag ccgggagcgg aagaactgat tggggagtgc 791401 tatgcggtgt tgagggaagg gtattaaata ggaaaagtcc agaaagtgat ttctggactt 791461 tttagtcttg ctctgtttta ttccttatcc gctcaatcac ctcatgcagc ccctcaggct 791521 tataaaactc caccggtgaa ctgcctttct caaacgaaat cgtctcggct tcaatcagcg 791581 cgacatagcg cccgtttact tttgcgagat gaatagaatc gccaaaatcc gctagcaatc 791641 ccttaatctc tgtttctccg actttcattt tcagctgggc ctctggcgtg tgctcgatga 791701 tttgggcgga ggcttcgatg acttgatggg tgtcgaggcg ctcttggatt tcccgttttt 791761 cgcttgcttc ccaaatctca atgtcgtgct cgaactgctt gagttcttcg ctgttgtctt 791821 caaatgtctc gtagacgtgc tcttgtacca tgttcatgac ctgatttttc atgatttctg 791881 gcatcgattc tccgtactcg acgaatttca gaaagtcctc aaaatagcgg gcgtgcgagg 791941 cctggtggat tttcagttca ccttcctcga ccattccttc ctctggcatg tacgggtatt 792001 ggatgctttt catgtttttt gtcgtgatcg ccatttcgac ttttttaatg agagaagacg 792061 cgtcagagat gcgggcgacc ttcggctcaa aatcacattt cataatgaag acaaatgact 792121 catcaaagta ttttctcggc acggccgaag cgacgagaaa cacgccgccg cgaaccgcgc 792181 ttgtgtcaag gtacgtgcgg acgaactgct cgctcagctc attgaagtct tcttttgttt 792241 ccgccagacg cgcgcggttg aacatgttgt agtttgggtt ggaatcgagc tcgtggccgg 792301 gctcgacgat aaaatggccg attttcgtcg gcacctgctc ggactgcgga tggcggtcgg 792361 ctttccgttt aacgattttt ttcagttccc cgtcgagaaa gtccttcagc tcgctttctt 792421 caaattctcc cgtatcaagg gtctggaagt gcttgaactg cttgttcgcc tgctcatctt 792481 tgccttccac ctgtatgaca taaaaggata aaaaccgaat ttcaaaatcc atatataaac 792541 tcaccttatt cgcgtattgt acagcttctc aagtatagaa aaaacagcga tcatgcgtca 792601 attgggagaa cggaataatc atgaccatga aagggaaatg tagtcaaata gaaggcattt 792661 catacggaaa ggaatggttc gatgaaggaa acaagcccga ttcctcagcc gaagacgttt 792721 gggccgctcg gcaatttgcc tttaattgat aaagacaaac cgacgctttc gctgatcaaa 792781 ctggcggaag aacagggccc gatttttcaa atccatacac ccgcgggcac gaccattgta 792841 gtgtccggcc atgaattggt gaaagaggtt tgtgatgaag aacggtttga taaaagcatt 792901 gaaggcgcct tggaaaaggt tcgcgcattt tccggtgacg gattgtttac gagctggacg 792961 catgagccta actggagaaa agcgcacaac attctgatgc cgacgttcag ccagcgggcc 793021 atgaaggact atcatgagaa aatggtcgat atcgctgttc agctcattca aaaatgggca 793081 aggctcaacc cgaatgaagc agtcgatgtc ccgggagata tgacccggct gacgctcgac 793141 accattgggc tatgcgggtt taactaccgc tttaacagtt actacagaga aacgccccac 793201 ccgtttatca acagcatggt gcgggcgctt gatgaagcga tgcatcaaat gcagcggctt 793261 gatgttcaag ataagcttat ggtcagaaca aagcggcaat tccgctatga tattcaaacg 793321 atgttttcgt tagtcgacag cattattgca gagcgcaggg cgaatggaga ccaggatgaa 793381 aaagatttgc tcgcccgcat gctgaatgtg gaagatccgg aaactggtga aaagctcgac 793441 gacgaaaata tccgctttca gatcatcacg tttttgattg ccggccatga aacaacgagc 793501 ggcctgcttt cctttgcgac ttacttttta ttgaagcatc ctgacaaact gaaaaaggcg 793561 tatgaagagg tcgatcgggt gctgacggat gcagcgccga cctataaaca agtgctggag 793621 cttacataca tacggatgat tttaaatgaa tcactgcgct tatggccgac agctccggct 793681 ttcagccttt atccaaaaga agacacagtc attggcggaa aatttccgat cacgacgaat 793741 gacagaattt ctgtgctgat tccgcagctt catcgtgatc gagacgcttg gggaaaggac 793801 gcagaagaat tccggccgga acggtttgag catcaggacc aagtgcctca tcatgcgtac 793861 aaaccattcg gaaatggaca acgggcctgt atcggcatgc agtttgccct tcatgaagcc 793921 acacttgtgt taggcatgat tctaaaatat ttcacattga ttgatcatga gaattatgag 793981 cttgatatca aacaaacctt aacacttaag ccgggcgatt ttcacatcag tgttcaaagc 794041 cgtcatcagg aagccattca tgcagacgtc caggcagctg aaaaagccgc gcctgatgag 794101 caaaaggaga aaacggaagc aaagggtgca tcggtcatcg gtcttaacaa ccgcccgctt 794161 ctcgtgctgt acggctcaga taccggcacc gcagaaggcg tcgcccggga gcttgctgat 794221 actgccagtc ttcacggcgt aaggacaaag acagcacctc tgaacgaccg gattggaaag 794281 ctgccgaaag agggagcggt tgtcattgtg acctcgtctt ataatggaaa gccgccaagc 794341 aatgccggac aattcgtgca gtggcttcaa gaaatcaaac cgggtgagct tgagggcgtc 794401 cattacgcgg tatttggctg cggcgaccac aactgggcga gcacgtatca atacgtgccg 794461 agattcattg atgagcagct tgcggagaaa ggcgcgactc ggttttctgc gcgcggggaa 794521 ggggatgtga gcggtgattt tgaagggcag cttgacgagt ggaaaaaaag catgtgggcg 794581 gatgccatca aagcattcgg acttgagctt aatgaaaacg ctgataagga acgaagcacg 794641 ctgagccttc agtttgtcag agggctgggc gagtctccgc tcgctagatc gtacgaagcc 794701 tctcacgcat ccattgccga aaatcgtgaa ctccagtccg cagacagcga tcgaagcact 794761 cgccatatcg aaattgcatt gccgccggat gttgaatatc aagagggcga ccatcttggc 794821 gtattgccaa aaaacagcca aaccaatgtc agccggattc ttcacagatt cggtctgaag 794881 ggaaccgacc aagtgacatt gtcggcaagc ggccgcagtg cggggcatct gccattgggc 794941 cgtcctgtca gcctgcatga tcttctcagc tacagcgtcg aggtgcagga agcagccaca 795001 agagcgcaaa tacgtgaact ggcgtcattt acagtgtgtc cgccgcatag gcgcgaatta 795061 gaagaactgt cagcagaggg tgtttatcag gagcaaatat tgaaaaaacg aatttccatg 795121 ctggatctgc ttgaaaagta tgaagcgtgt gacatgccgt ttgaacgatt tttagagctt 795181 ttacggccgt taaaaccgag atactattcg atttcaagct ctccaagagt gaatccgcgg 795241 caagcatcga tcacagtcgg tgtcgtgcgc ggcccggcgt ggagcggccg tggcgaatac 795301 aggggtgtgg catcaaatga tttagctgag cgtcaagccg gtgatgatgt cgtgatgttt 795361 atccgcacac cggaatcccg gtttcagctt ccgaaagacc ctgaaacgcc aattattatg 795421 gtcgggccag gcacgggagt cgcgccattt cgcggtttcc ttcaagcccg cgatgtttta 795481 aagcgggagg gcaaaacgct cggtgaggct catctctatt ttggatgcag gaacgatcgg 795541 gattttattt accgagatga gcttgagcgg tttgaaaaag acggaatcgt cactgtccac 795601 acagcctttt cccgaaaaga gggcatgccg aaaacatatg tccagcatct catggctgac 795661 caagcagata cattaatatc aatccttgac cgcggtggca ggctttatgt atgcggtgat 795721 ggcagcaaaa tggccccgga tgtggaggcg gcacttcaaa aagcgtatca ggctgtccat 795781 ggaaccgggg aacaagaagc gcaaaactgg ctgagacatc tgcaggatac cggtatgtac 795841 gctaaggatg tctgggcagg gatatagata aagaagactg gagacatcca gtctttttag 795901 tcctttcgaa aaaatggtga tcgcgctaaa cattgatgca tacaataact tcagtccgcc 795961 ggaagggcgg gctgtctgca aaacctattt ttcgtttttg ctagtttatg ttattcttat 796021 actcggtatc tatttctttt ttcaaaggca cacatgacaa aagaaatcct ttttttattt 796081 ccgagaaaaa aatgtgaaac gaaatgaagg tttctttcgt ccagtgattg gtttccaaat 796141 ggttgtaata aaaatgatat ggtgcgaaac ataaatattc cggcttgccg cggtgtattt 796201 attgttgtgt gatgccttga ttttgtttgg aaagaaggaa ttggaaggca ggatataaag 796261 agcaggtaaa tatgaatgaa gaacttaaag tgtttaagaa agtagaggtt gccatgaaga 796321 aacttttttc ttacaaactt agcttttttg tgctggctgt tatactgttt tgggcaaaaa 796381 cgtatttatc ctacaagact gagtttaatc ttggggtaaa aggcacaact caggagatcc 796441 tcctgatatt taacccattc tcaagcgccg tcttcttttt aggactggct ttgctggcga 796501 aagggcgtaa atcagccatt attatgctga ttatcgattt cttgatgaca tttgtgttat 796561 atgcaaatat tttattctat cgtttctttg acgatttctt gacgttcccg aacattaaac 796621 agtccggaaa cgttggaaac atgggagacg ggattttcag tatcatggcc ggtcatgata 796681 ttttctattt cttagatatt atcattttga ttgcggtatt gatctggaga cctgaattaa 796741 aagaatacaa aatgaaaaaa cgctttgcat ctttagtgat cctttctggg atcgcactgt 796801 ttttcatcaa cctgcactat gcggaaaaag accgtccgca actgctgaca agaacgtttg 796861 accgcaatta tattgtgaaa tatttaggtt tatacaacta caccatttat gacggtgtac 796921 agacggctca aacagagacg caaagagcct atgcaagcag cgatgattta acaagtgtcg 796981 agaattacac gacgtctcat tatgcgaaac caaacgccga gtacttcggc tctgccaaag 797041 gcaaaaatat cattaaaatt cacctcgaaa gcttccagtc attcctgatt gactacaagc 797101 taaacggtga agaggtgacg cctttcttaa ataaacttgc gcacggcggg gaagatgtga 797161 cgtattttga taacttcttc catcagacag gccagggaaa aacatctgat gccgagctga 797221 caatggataa ctcgatcttc ggtcttcctg aaggctccgc gtttgtgacg aaaggcgaaa 797281 acacctacca gtcgcttcct gcgattttag accagaagga aggctataca agcgccgtcc 797341 tgcatggtga ttacaaatcg ttctggaacc gtgaccagat ttacaaacat atcggatatg 797401 acaagttctt cgacgcaagc acgtatgata tgtcagatga aaatgtgatt aatatggggc 797461 ttaaggataa gccgttcttt acagaatcga ttccaaagct tgaatctctt aaacagccat 797521 tttatgcgca tttgattaca ttgacaaacc attatccgtt taaccttgat gaaaaagacg 797581 cgtctcttaa aaaagcgaca acaggcgata acacagttga cagctacttc cagacagcgc 797641 gttaccttga cgaagcgctt gagcaattct tcaaggagct gaaggaagcc ggcctgtatg 797701 acaactcagt catcatgatt tacggtgacc ataacggtat ttctgaaaac cataaccgag 797761 cgatgaaaga gattcttgga aaagagatca cagattatca aaacgcacag aaccagcgtg 797821 tgccgctgat gatccgcgtt cctggcaaaa aaggcggagt gaaccatacg tatggcggcg 797881 aaattgacgt catgccgaca cttctgcact tagaaggaat tgattctcag aaatatatca 797941 actttggtac tgatttattc tctaaagacc acgacgatac ggtggcattc agaaacggag 798001 acttcgtaac gccgaagtac acatcagtcg acaatatcat ttacgatacg aagacaggtg 798061 aaaaactgaa agcgaatgaa gaaacgaaga atctgaaaac aagagtgaac cagcagctga 798121 gcctttcaga cagtgtcctg tacaaagact tgctgaggtt ccataaacta aatgatttca 798181 aagccgttga tccgtcagac tatcattacg gcaaggagaa agaaatcaaa taagatgaaa 798241 aagagccttg agcgggcgca ttgccttcgc tcaaggctct ttttttggtt atacaaccaa 798301 cttgaaaaaa tagattccat ttggtcacca aggctggctt tctctcatat cattacagta 798361 gattttgaaa ccggattgaa atcggacaaa ttatcgggga aatgccttga tagattgtga 798421 agatgtacca ggtttcgaac tcaatattca tagagatgag gggtagagat gaaagcggtc 798481 attctctgcg gcggaaaagg aacgagaatg agtgaagtca cgaatgacat tcctaaaccg 798541 ctcgccatga taggcggcaa accgattcta tggcatatta tgaaaattta tcagtactac 798601 ggagtaaacg agtttattct gcttttgggc tataaaggag aaaaaatcaa ggaatacttt 798661 ctcgactatg aatggaagca caacagcctg acactcgaca gctctacggg agaggtacag 798721 atgctggggc agcctgaaac gtggaaaatt acgtttttgg agactggggt agatacgctg 798781 acagccggaa gaatcttgca ggcgaaagac tatatcggtg atgaaacatt tctgctcacc 798841 tatggagacg ggctggccaa tatcaatctt ttccatctca tcagctatca tcagacaaaa 798901 ggtgctgccg cgactgtcac cggcattgac aaagtctcgc agtttggcac cttgacagtt 798961 gaggatggca tggcgaaaac attttctgag aagacatcaa gtgatggaat catcaacggc 799021 ggattcttcg ttcttagtcc aaaggttttc gattatttgc cgaaggacgg gaacacgatg 799081 ttcgaagatg aaccgctgaa gaaccttgcc aaagatgggg agcttgctgt gtaccgccat 799141 tacggatttt ggacggccat cgatacgtat aaaaatctct tagaagtcaa caaaatgtgg 799201 aatcaaggac aacaagtatg gaaggtatgg tgaattgatt tgagtttctg gaaaaataaa 799261 aacgtatttg tcacgggatg cacaggtctt ttaggaagct atttggtgaa agagctgatc 799321 gaacagggcg caaacgttac ggggctagtc agggatcatg tgcctcaatc caatctttat 799381 cagggagaac atatcaagaa aatgaacatc gtgcggggct ctcttgagga cttggctgtg 799441 attgaacgcg cgcttggcga gtatgagatc gacacagtct ttcatcttgc tgcacaagcg 799501 attgtcggcg tggcaaaccg caacccgatt tctacctttg aagcgaatat cctcggcacc 799561 tggaatattc tcgaagcctg ccgcaagcat ccgttaatta agcgggtcat tgtcgcttca 799621 agtgataaag cttacggcga tcaagaaaac cttccatacg atgaaaacat gccgctgcaa 799681 ggcaagcacc cgtacgacgt ctcaaaaagc tgcgcagatc tgatcagcca cacctatttt 799741 cacacgtacg ggcttccggt ctgcattacg cgctgcggaa acttatacgg cggcggagat 799801 ttgaacttca accgcatcat tcctcagacg attcagcttg tgctgaacgg ggaagcgccg 799861 gaaatccgaa gcgacggcac atttgtacgg gactacttct atattgaaga cgccgttcag 799921 gcttatctgc ttcttgcaga aaaaatggaa gaaaacaatc ttgccggaga ggcctttaac 799981 ttcagcaatg agatccagct gaccgtactt gaactggtag agaaaatatt aaagaaaatg 800041 aacagtaatc tgaaacctaa ggtgctgaat cagggaagca atgaaatcaa acatcaatat 800101 ttatccgcgg aaaaagcaag aaagctgctg aattggacac cggcctacac tattgatgag 800161 ggacttgaaa aaacgattga gtggtatacg gaattcttca aaaagtaatg tgaaacgagg 800221 tgaacaagac tgtgaccagc gcgtattgca ccgttttatc aaaaggaaga ttatatcagg 800281 cagtcgcttt gtttaagtcg ttagagcaag ttgatcaaga cagtcccatt tttatacttt 800341 gcatggatga agatacgcac cgcgtgttac agaagctgaa gatgaagcag ctgaaccttg 800401 tgccggtggc cgctcttgaa aatgaattgc tgctgaagct gaaggaaact agagatcaaa 800461 gtgagtattg ctggacgatg aagccgatct ttctgcaagc tgtgctgaac agcaatcctg 800521 agctggagcg tgtgacgtat attgacgggg atctcttttt ctatgcagat ccatcgccga 800581 tttttgaaaa ccagccggac tgctcggtgt tgctttcacg aggggatatt gtaatccctt 800641 cttttgagaa agagcagatt gacatgctgc agcgtctttt aggcagatat aattccgggt 800701 ttatcagctt caagcatgat gatgcaggca cggattgctt ggagtggtgg aaggaacgct 800761 gtcttgagga atgcaaaaat gcaccgggtg aagggaaatt cggtgatcag ggctatttgg 800821 attatatgtc tgagctgttt ccgaatgtgt gtgacattac aacacccggc gtgaacatcg 800881 gccattggaa ttatggacag catacgtttt cctggaaaga tggccggatc gtgctggagg 800941 atggcagtcc gctgatcttt tatcatttca gcggataccg aatcgtcagc atcaatgaaa 801001 tcaaacagat tcatgaaaca acccgcacag atctgccgtt tgtgcatgaa ctgtatcaag 801061 agacactgcc gcatatcatt cagcacatgc aaacgttaga ccctgaattt aacggttttg 801121 cttcaaaaga tgacaacaaa taaatgagta aatacaggaa gtgaaaatga agtgaaagca 801181 agcgttatta ttcctgcata taattcgaag gagcgtcttt acaacagcct tctgtcatta 801241 aaccagcagg agtgcgatga agaatttgaa gtcattgtag cggacaatgg ctctgaggac 801301 gggacgctct cgatgcttga gtcatttcaa gctgattttc cgctgatctt tacacggatt 801361 aaagaaaaca ggggcattgc gtacggacga aatcaggcgc ttcgcaatgc cagaggagac 801421 atcctgattt tccatgacag cgatatgctt gcggcaaagg accttgtggc aaaacatatt 801481 aaagcccatg agaacgaaga gaatctcgtc gtgtgcgggt tgttttggaa acggatctac 801541 agtttttact atgaacgatt tgaagaagaa cataaggaac agctcgcaaa gctcacaggt 801601 gaaatgccga agaaagacaa acaaaagctg ctggaggaag cggacatcaa aaacggaagc 801661 tttcttgata aaagctttga cctcgatacc gactttatag acgtgctcaa gaagatttta 801721 gatgagtacg gcgatgactt gaaaggctat catatgccat ggcgcttttt tatcacgaat 801781 aattcctctg tgaaacgcaa gcatgtggtt gacctcggtt tatttgacga aggcattgtg 801841 cggtacgggt ttgaggatta tgacctcggg atcaggcttc atcaggccgg attgaccttc 801901 aggcttcgcc gtgatattgt cagtgttcat caggaacatc caagcaattg taagtctgta 801961 gacgatattc gggcaaacat tgcctatatg tgcgataaat acaataacat ccgctcctta 802021 gacgttcatc tcgcttttaa tgggccgttc ccgcctgaca tgacgaacag aatcatggct 802081 gatattcaaa agctgctgga atcacagaaa tatgatatgc tgctgaatct gtttcttgag 802141 cttctgcatg ttgttaaaga gcgcaacatt gatccggatt ggcgaaagaa atccccaagg 802201 gtgacggcga aaagctttga tttgcaaact gtccgcaagc ttctgcctaa ggcgaagaaa 802261 aagctaggcg tgaacgattt tgccaacgca ctgtatgcgc ttgtcaacga tttgctgcac 802321 gtggatctta gatcattgga tgtggtataa gtgagtacat ttcatttttc aacgatagtg 802381 tcaaggacac atatctttaa gctcatgcct atgattcatt ctctccatga gcattgcgat 802441 gattttcatt tatatgtgct gtgtgtcgac cagaaagcgt atgaattgct tcagcacgtt 802501 ccatgggagc atgtaacctt tgtgcagctg catgaaatgg aagacccgga gctgttgaaa 802561 gcgaaaagca acagaacgtt tcatgaatat tgctggacgt taaagcccgc ctttttgttt 802621 catgtgatga gcaagtggga tgacgctgaa tactttgccc atatggatac ggatctattt 802681 ttcttttctg atccggcacg tatttttgca gaaaacccaa cggcgtctct gtatttgact 802741 gatcatcgta attcgccgcg cttcatgtcc tactacgacc gaaccggacg ctttaataca 802801 ggctttgtcg gcgccggtaa tacaaaggaa gcatatgaag cggtgtggca gtggagacag 802861 gactgtattg aattttgcac ggtcgaaatg gatacggaac gaaagacata tggtgatcaa 802921 agatatgtgg agaaatggcc ggagcagttt aaaggtgttc atgttgtcaa atccatagga 802981 gccaatacag cgctttggaa tatcgaaaac tataaggtcg ggcaaaagga cggccgcgtg 803041 tatatagatg aaacgccgct gattttctat catttctctg ggtttacgct ggtgacagaa 803101 aaagagttta atctttgctg gtactaccgg attgaagacg aagcgacaat taagatgatt 803161 tatatgccct atatattaaa tctgaaaaga tggattgatg aaatacagtc ggcgtttccg 803221 gactttgcgg atggctttat cccgaagcac gcagtgcctg acactcattt tatccagctg 803281 gattaaaaaa ccccctgccg cctggcaggg gttttttcag ctatgccatt ctctcagctt 803341 ctggtcactt ggcaatagga aggcaaggat gccgaggaca gggagaaagg caatggcgat 803401 catcgtcggg gtcagtcccg cggcatcaat cagagcgccc agcgccacag cgccgattgc 803461 gcccatcccg aaggcaagcc cgacggttaa accggacatt gtgccgattt ttccaggaac 803521 tagctcctgt gcgtagacga ccgttacaga aaagctcgac atcagaacca agccaatcaa 803581 tgcgagcacg ccgtaggcga gaaccgggcc ggcaaatggc agcacaatcg ccagcggcgc 803641 cgagcataac agcgaaccga ggataacgaa gcgttttcca aaacggtctg caagcgggcc 803701 gccgagaaac gtgccgatcg cgccgaacag caagaagaca aaaatatagc tttgtgcctg 803761 ctgaatgctt acgtgatagg tatccatcgc gtaaaacgtg taaaagttac cgatcgcact 803821 cgtataccaa gaacgagcaa aaatgagaaa tataataata ataagagcag atacaacaga 803881 tttggtgatg gccgtgtttt cagccgtttt cttttgcttg cctgatttct gggcaaggct 803941 gccgagacgt gaggcgtacc atttcgcaat atacatgaga aacataacag caagcgcggc 804001 gacaagcgtg aaccaaacag cgccgaattg cccgagcggc acaaggatca gcgcggtgat 804061 cagcggtgcc atcgcctggc ctgagtttcc gcccacctga taaatcgatt gggcgagccc 804121 gcgttttgtg ccggcggcca tatacgccac acgggagccc tccggatgga aaatggccga 804181 gcctaatcca atgaaaaaca cacagcataa gatcgttatg aatgacgggg caaatgcaag 804241 gcccaaaatg ccaagcatgc tggcggtcaa accgactggc agcgcatacg gccgcggccg 804301 tttatcggta taccagccga caacaggctg catgacggat gacaccatgt ttaatgtgaa 804361 agcaatgatg ccgagctgtg taaacgtcag gctcatggag cgttccaaaa tagggaacat 804421 ggccggaatc acagcctgaa gcgaatcgtt gagcatatgg caaattccga taataatcaa 804481 aatcggatac accgtggtgc ctggtttttg aactgttttt tcttttaacg gggcggcgat 804541 agccattgag tctcctcctt acatatataa ccaaagcata ccaccatatt attcataagg 804601 tgaagaattt atcaagagga aaaaagattc ttatgaaaga aataccgtca gcctgattag 804661 cagctgacgg tattttcgat attcaaaatg tgatatagct cttcaagctt acgaatctca 804721 taggttggta tgatctctgg cacattcggc ttcatgtcag ggttcatcca gcaagtatca 804781 agcccggcga gctgtccgcc tttgatatca gcagttagtg aatccccgat gattaatgtg 804841 tgctctgctg aaaattgagg aatccgttca aacacgtaat tgaaatattc cttcatcggc 804901 ttttggaagc cggtgtcttc agaaacgaaa atgtccttga agaatggaaa taatcctgaa 804961 tcacggagac gcttatattg tgtgtgagac acgccgtttg tcacgatgta caaatcaaac 805021 tgttgctgca gatttgagat gagatcaaat gcaccgtcaa taagctgatg tccttcttca 805081 agaaagcggc ggtatttttg ctcaagcaaa gcgccgtccg cttcgtaacc gtactccttg 805141 agcaaagcgg aaaaacgtgt gtttacgact tcatcccgtg tcatcttacc ttcttcaaag 805201 gctctccaga gaccttgatt gatggtttta tactgcgcct tcatgtcatt tgttaaagga 805261 atgttctgat cttcaaacag caaacgcagg gctaaagctt ctgccgcttg aaaatcaagg 805321 atggtatcat ctacatcaaa taataaagtg cggtatcgct tcatctgtgt gtctcccttt 805381 ctcatatgta ttcaaagtat agcacataaa aaaaggaaaa agccggcggg tgaggcaccg 805441 ccggctgaaa agagattatt tgtttaataa gctgtgtttt ctcgaatata ggaagtaaac 805501 cagcgttccg acagcgatcc agatgacaaa tgaaagccat gtgacgccgg gaaggctgta 805561 catgaaccaa aggcagatgc ctgcgctgat aatcggcaca accggaacga atggcactct 805621 gaaggacgct ttgatttcag gatgtttctt tcttaacaca atgacagcaa tggaaatgac 805681 cgtaaacgcg gcaagtgttc ccatgttcac cagatgggcc agcgttccga ggttaataaa 805741 gccggcgatt cccgctgcaa cgatccctgt cagccatgtg ttgcggaacg gggttttaaa 805801 tgacggatga acctttgcga acaatccagg cagaaggccg tctctgctca tggcaaatgt 805861 caagcggacc tgtgcgtaca gcaaagcgag catcaccgtc gtaatcccga taatcgcacc 805921 gacagaaata attccggcaa cagcgtcctg tccgacgaat ttcagcgcaa aggatacagg 805981 atctccgaca ttcaatttgg cataaggcat catgcctgtc agcacaagcg ataccgcgat 806041 gtacagaacc gtacagacgg ctagagctga aataatgccg acgggcatgt ttttttgcgg 806101 atttttcact tcctctgatg cgttagaaac cgcgtcaaac ccaaggtacg cgaagaatac 806161 agtggcagcg ctaagtatga cgcctttcat cccgaatggc ataaaaggag accagttatc 806221 cggtttcaca tagccgatgc cgacaataat gaacaataat atgatcgcga ttttcatcag 806281 tacgatgacg ttgttaaagc gtgtgctttc cttgacgcct ctgctgacaa tcgcagtgat 806341 gaggagaatg atcaccgcag ccggaaggtt aaatacggcg cccgccatgc ttcccggcgc 806401 tcctgtcagt gcagccggaa tatgaagatt gaagccggca agcagtgatt gaaagtatga 806461 agaccagccg gtggcaaccg ccgacagtgc aatgacatat tcaagcatga gatcccatcc 806521 gatcaaaaag gcgagcagct ctccaagtgt cacgtatgag tatgagtaca cgcttcccga 806581 aatcggaatg gaagacgaaa actcagcata acagaaagca gccagcgcac aggcgagccc 806641 cgctaaaata aacgatatga tgagggcggg acctgcaccg gtcgctgcca ctgttcctgt 806701 aatgacaaaa atccctgtac cgatgacaca accgataccg agcaaggtta aatcaaatgc 806761 gcttaacgta cgggcaaggc tttttgactt gctctgcgca ctcaatgttt caagcggttt 806821 ttttctaaat aatgaactca tcaaaagttc ctcctagaaa tattcaaaat attctaatca 806881 ttatatgcag ttcttgttgt attatattgt cgaaatttga cgtagtcaat aaaatatttt 806941 tctgctttaa atgatagaag cgaaacagcg ttgtcgtatc ataggatagt aatttttact 807001 aatcgtatat tcaattttat gcaagatgaa ccgatagaaa aaatagattc gcccatattt 807061 tgatttgcgg ttataaagga gatgctgacc atgtttcaat atgaagagtt gaataaacag 807121 tttatcggcg ggaaatggca ggagggcagc agcccaaatg tattggaaaa caaaaatcct 807181 tatactcaaa aaacattcac aacattccgt aaagcgactg ctgacgatgt agatgaagcg 807241 tatcgggcag cggcgctggc aaagaaaaaa tgggatgcgg tcaacccgtt cgagaaaaga 807301 accattttag aaaaagccgt cacgtatatt gaagaaaatg aagaagccat tatttatttg 807361 attatggagg agctaggcgg tacaaggctc aaagcagctt ttgaaatcgg tcttgtcaaa 807421 aacatcataa aagaagcggc aacgttccca atccgcatgg aggggaaaat tcttccgtca 807481 acaatagatg gcaaggaaaa cagattatat cgcgtgccgg caggcgttgt cggtgtcatc 807541 agtccgttta acttcccatt ctttttatct atgaaatcag tggcgcctgc actcggagcc 807601 ggcaatggcg ttgtgctaaa gccgcatgag gaaacgccga tttgcggcgg aacgctgatt 807661 gcgaaaattt ttgagaacgc gggaattcca gcggggctgc tgaatgttgt tgtcacagac 807721 attgctgaaa tcggcgacag cttcgttgag catccagtgc cgcggatcat ctcatttacc 807781 ggttctacga aagtcggcag ctacatcgga cagcttgcga tgaagcattt taaaaagccg 807841 cttcttgagc ttggcgggaa cagcgccttc atcgtacttg aggatgcaga tatagaatat 807901 gcggtcaatg cggcggtgtt cagccgattt acacatcaag ggcagatttg catgtcagcc 807961 aaccgcgtgc ttgttcattc ttctatttat gacaagttcc ttgagctgta ccaggcaaaa 808021 gtggaatcgc tgaaagtcgg cgacccaatg gaccctgata cgattatcgg gccattaatc 808081 aacagcagac agacggacgg gctgatgaag actgtagagc aagcaattga agaaggcgct 808141 gtaccagtga agcttggcgg atttaacggg acgatcgtgg aaccgacgat cttaaaagac 808201 gtcaaaccgt tcatgagcat tgccaaggaa gagctgttcg gaccagtcgt ctcctttatg 808261 aagtttgatt cagaagacga agcggtggat atcgcaaacg aaaccccgtt tggcttgagc 808321 ggtgccgtac atacgtcaaa tcttgagcgc ggcgtggctt ttgcgaaacg cattgaaaca 808381 ggcatgattc acgtcaatga cacgaccatc aatgatgaac cgaatgtagc cttcggcggt 808441 gaaaagcaat caggcctcgg ccgtttaaac ggtgagtgga gcctcgaaga atttacaacg 808501 ctgaaatgga tctcggtcca gcacgaaaaa cgcagcttcc cttattaatg aaaaggagtg 808561 aatggaattg accataaata cggaaaaaga aaccgcagat attctggacg catttatcaa 808621 agtagcccct tatttaaaca gcctggttca ggatgatatt acaatcggca tttatgatac 808681 ggaaaaactg ctcgtgaata taccggccaa aaccttttcg ctgaacgtaa aagccggcga 808741 tccgctgcag gaaggggata tcatcacaga tgccatccgc agcaatcaga agaagacgag 808801 catggttccg aaagaattgt tcggcttccc attgatcgcg cgtgccatcc cgctgcacga 808861 cgagaatgga agagtcattg gaggcgtcgg cctcggaacg agccttgagg agtcgtcaaa 808921 gctgcatgat gtcgcggaaa gcttatcagc tgttgttgaa caaacagccg cggctatttc 808981 cgacatttct gaatcaatta acgggttttc aactcaaatg tcgggcattt cctctcaggc 809041 gaaaaaagta agcgaaagcg ccggtgaaat cgccgatatt tcagtaactg ttaaaggcat 809101 ctcggaccaa agcaatctgc tcggcttgaa cgccgcgatc gaagcggcaa gagcagggga 809161 gtccggaaaa ggattctctg tcgtcgcaga tgagatcaga aagctagcga cgcattcaaa 809221 agaaaatgtc ggccaaattg accagattac gaaaaaaatc cacagcctgc tgaaagggct 809281 ggaggaatcc attgagtcga ttaaccagca tacagacgga caagccgctg ctgttgaaca 809341 aatttccgcc acgatgcagg agatttcagg aagcgcgcag catcttgcga aaatggccga 809401 aaaagcgctt gaggaagagt aagagaccgg ggacaaacat ccccggtctt tttcttatcc 809461 tgcatttcca tgaaattcgt ctgacgtttt actagtttta ttccagcggc tgatttaaaa 809521 tgtacacatg aacttacgtg aggattgata ggaaccatga gcatattaaa agcggaaaat 809581 ctttataaaa catacggaga taaaacatta tttgaccata tctcctttca tattgaagag 809641 aatgagagaa tcggattaat cgggccgaac ggaacaggaa aatcaacgct gttgaaagtg 809701 attgccggct tggaatctat cgaagaagga gaaatcacga aatccggaag cgtgcaggtc 809761 gaatttcttc atcaagaccc ggagctgcct gcggggcaaa cagtgctgga gcatatctat 809821 tccggtgaat cggctgtgat gaaaaccttg cgtgaatatg aaaaagcgct gtatgaactg 809881 gggaaagatc ccgaaaatga acagcgccag aaacacctgc tggcagcaca agcgaaaatg 809941 gacgcgaaca atgcatggga tgcaaacacc ttggcaaaaa ccgtattgtc taagctgggc 810001 gtcaacgacg taacaaaacc ggtcaatgag ctctcaggcg gccagaaaaa acgggtggcc 810061 attgccaaaa acttaattca gcccgctgat ttgctcattt tggacgagcc gacaaaccat 810121 ttggataatg aaacgattga gtggcttgaa gggtatttaa gccaatatcc cggcgccgtc 810181 atgctggtga cgcacgatag atatttctta aaccgtgtca ccaaccgcat ttatgagctt 810241 gaaagaggca gcctctacac ttacaaaggc aactatgaag tgtttttaga aaaacgcgcg 810301 gaacgggaag cgcaggctga gcaaaaggaa acgaagcggc aaaacctgct gcgccgcgaa 810361 ctggcttggc tcagacgagg agcgaaagcc cgctccacaa aacaaaaagc gagaattgac 810421 cgggtagaga cgcttaaaga gcagacaggc cctcagtcat caggttcact cgattttgcc 810481 attggctcgc accgtctcgg aaaacaggtt attgaagcgg agaacgtcat gatcgcttat 810541 gacggccgca tgctcgtcga ccgttttaat gaacttgtca taccaggtga acggatcggg 810601 atcatcgggc cgaacggcat cgggaaaaca acgctgttaa atgcccttgc cggccgtcat 810661 acgccggacg gaggcgatat tacgatcgga cagacggtca gaatcggcta ctatactcag 810721 gatcatagtg aaatgaacgg tgagttaaaa gtcattgact atataaaaga aacggcggag 810781 gtcgtaaaaa cggcagatgg cgatatgatt acagctgaac aaatgctcga gcgtttcctc 810841 ttcccgcgtt cgatgcagca gacgtatatc cgcaagctgt ccggcgggga aaaacgccgt 810901 ttatacttgc ttcaggttct catgcaggag ccgaatgtcc tgtttctcga tgagccgacg 810961 aacgatttgg atactgaaac attaagcgtt cttgaggatt atattgacca gttcccaggc 811021 gtcgtcatca ccgtatccca tgaccgctat ttccttgacc gcgtcgtcga ccgtttgatt 811081 gtatttgaag gaaatggtgt catttcccgc tttcaaggct cctatagcga ctatatggag 811141 gagtcaaaag cgaaaaaagc ggccccaaaa ccggcagctg aggaaaaaac ggctgaagcc 811201 gagccgaaga aaaaacggaa aaagctttct tacaaagacc agttggaatg ggacggcatc 811261 gaagataaaa ttgcccagct ggaagaaaag catgaacagc ttgaagctga catcgccgca 811321 gcaggcagtg attttggcaa aatccaagag ctgatggccg agcaggcgaa aacggcggaa 811381 gagcttgagg ctgcgatgga ccgctggaca gaattgtccc tcatgatcga agaactggaa 811441 agctaaaaag cgtggccgca gcaggccgcg ctttttttca cataatggac aaaaacgaac 811501 cggcctgctt atgttaggat aaagttgtgt gtcagcggca catggaaaac taacggagat 811561 gatgaagtat gacatgggcg atcgtgatgt taattctcat gagtctggtg aaaatcgtat 811621 taacctgtct tcctacaggc gtcatagaat ggctgctcgg caaatttgaa gtgcacgcca 811681 agctgagtga cgaaaatgcg agtctctctc tagatggaaa acgcctcgag ggtgcagaga 811741 agcagaaagt gattgatcaa tttaacgaag ctatcttcct ggaaaaatat tatatctatc 811801 caggtgatga agagcgttat ttacatccgg aaaacggcgg cacgcctctg gtgatagata 811861 caaaaaaagg aaaaaaagac gtgaagctgt tcgtgtaccg ctacgacgac catatcgacg 811921 tcgtgaaaca gtacaagaag aaagtgatcg cgtatcgagt gctttctgaa agccttcaaa 811981 aagagtctct gtcagtggcg ggaagtttag cttaaacagg aaagtgaaag acgggtgctg 812041 tatgctgctc gtctttttta ttgtttttta aaacttaacg tttacgttaa ggttcaaaag 812101 gtgtataatg gtaacagaaa cggcgaaggg ggatttacct tggaatggat gaagattgat 812161 caagtggcca aaagaagcgg gctgacaaag cggaccatcc ggttttatga agaaatcggc 812221 ttgattccgg cgccgaaacg gacagacggc ggtgtaaggc tttattcaga ggatgatatg 812281 gaggagcttg agaaagtcat cagcacaaaa gaggtgctcg gtttttccct tcaggagctt 812341 cagcatttca tggaaaccag ccgccagcta gagttaaaca aagaggggta tttgttgtca 812401 ctggatccta aggaacggaa agaaaaactg gaggaaattc aggaaaccct gaatcaccag 812461 ctggatttga ttgatgagaa aatccgcaca ttccaaagct ttaaagaacg cctgcagggc 812521 atgaaaggca aagcggaacg cgccattcaa tcaatcgaat gaaaagtttg ttaaacgcta 812581 tttttgtagc gtttctttta atggaataaa gatggaggtt aggtcaaatg gataagacaa 812641 cacaagtgaa tcagaaaacg ggtttgctca gccagccaaa agcggtatgg gctgtcgcgt 812701 ttgcctgtgt gatttctttt atgggaatcg ggctggtcga tccaattctt ccggccattg 812761 ccgcacaatt gcatgcttca cctagtgaag tatcactctt gtttacaagt tatttgcttg 812821 taaccggatt tatgatgttt ttctcaggag ccatttccag ccgcatcggc gcgaaatgga 812881 cattaattct cggacttatt tttattattg tgtttgcggg gcttggcggc agctcaagct 812941 caatcgctca gttagtcggc tatcgcggcg gctggggatt agggaatgct ttgtttattt 813001 caacagcgct tgcggtcatc gttggcgtgt cagtcggcgg cagcgcccaa gcgattattt 813061 tgtatgaggc cgcgctcggt ctcgggattt ctgtcgggcc gcttgcaggc ggagagctcg 813121 gaagcatttc atggcgcgca ccgttttttg gagtatctgt cctgatgttt attgcgttaa 813181 tcgcgatttc tttcatgctt ccgaagctgc cgaaaccggc gaaacgcgtc ggtgtgtttg 813241 atgcgatgaa ggcactcaaa tataaaggcc tgctgacaat ggcggtatcg gcattcctat 813301 acaactttgg attttttatt ttgctagctt attctccgtt cgtactggat ttagatgaac 813361 acggtcttgg atatgtcttc ttcggctggg gccttctgct ggcgattacg tcagtcttta 813421 cggcgccgct cgtgcacaaa gcgctgggca cagtgcgttc gctagtcgtt ctctttatcg 813481 cctttgcggc cattctcgtt attatgggga tctggacaga ccatcagact ttgattatta 813541 catgtatcgt tgtcgctggt gctgtcctcg gtatggtgaa tacgatcatg acaaccgctg 813601 tgatgggttc tgcgccggtt gaacgttcaa tcgcgtcttc agcctacagc tcagtccgct 813661 tcatcggcgg cgcgctcgcc ccgtggattg caggaatgct gtcagaacac tttactgcaa 813721 gcacaccata tacagtaggc ggaatcgtcg tttttgtcgg catgcttgtc cttctcatgg 813781 gacgtaaaca tcttgctgga attaaggcgg ggcattaata acgaaagaca ctgcgcatat 813841 gcagtgtctt tttattcgtt ataatgcatc ataatcgaat tggtgcagga aaggacaacc 813901 tttatgacac aattttacta ttttccggct gaaaactccc tttagaaacc ggttttttcg 813961 gtcagcaaga acggcgttcg cggaaagggc atccgcttcg gtcaggcatt gatgcggctg 814021 ggatttatct tgcagaagct gagaatgtgt ccgttcattt acgattgcca tttcagtgat 814081 ggttcatgct gtagagggga cgtttgccat ggataaggca aaacctgacg aatatgatca 814141 gaaatgttta gaaacgctct atcaatacat acacagcgtc atgaaaaaca gcttttctcg 814201 gtcgagtggt ttaccgcttg ggaagatgag gaggattttg agctgtctgc caaaagagag 814261 ctgacacttg atgaattcac atctccattg cagctcattt taaaagacag agagcttttg 814321 agaatcgttc agaaaaaatg gcagtaaaaa acccgccctt tagcaggcgg gtttttttat 814381 aaattaaagc actttcgtcg tccaagactc gcagttccac gtttctgtcg caatatccat 814441 ataaaagtct ggctcgtggg aaatgagcag aatggagcct ttatattctt tcagggcgcg 814501 cttgagctct tccttggcat cggcatccaa gtggtttgtc ggctcatcga gcaccagcag 814561 gtttgtttct gagttgatta gcttgcacaa tctgactttc gctttttcgc ctccgcttaa 814621 tacggagacg cggctttcga tatgctttgt cgtcagcccg cattttgcca gagcggcacg 814681 gatttcatac tgcgtataag aagggaattc gctccatact tcttcgatgc acgtattgtt 814741 gtttgtttcc ttgacctctt gctcgaaata gccggtatag atgtgctcac cgcgttcaac 814801 agagccttcg agcggctgga tttcaccaag caaacttttc agcaatgtcg tttttccgat 814861 cccattcgcg ccgtaaaggg cgattttttg gccgcgctcc atgcggaggt tgagcggacg 814921 ggacagcggg gaatcgtaac cgatcacgag atccttcgtt tcaaaaatca gcttgcctga 814981 cgttctcgcc ggcttaaagt ggaattccgg ctttggcttt tctgccgcaa gctcgatcat 815041 atccatctta tcgagtttct tttggcggga catcgccatg tttctcgtgc tgacacgcgc 815101 tttgttgcgg gcgacgaaat ccttcagctc cgcgacttcc tgctgctgct ttttgtaggc 815161 cgcttcaagc tgctgttttt tcacctcgta gacttccata aactgatggt agtcgccgac 815221 ataacgtgtc agctcttgat tttcaacgtg ataaatcagg ttgatgacac tattcaagaa 815281 cggaatatcg tgggaaatca ggatgaacgc gttctcgtat tcctgcaggt agcgtttcag 815341 ccattcaata tgctgttcat caagatagtt ggtcggctca tcgagaagca gaatttccgg 815401 cttttcaagg agaagcttag cgagaaggac ctttgtgcgc tgtccgccgc tcaaatcggt 815461 gacatctcgc tctaaaccga tatcgctcaa accgagaccg cgggcgattt cttccacctt 815521 ggaatcaatg acataaaaat cattgtttgt cagcgcgtct tgaatgacgc cgacttcttc 815581 aagcagcttc tcgagctcgt cgggatcagc ctcgcccatt ttgttgtaaa tctcgttcat 815641 ttcctcttcc atcgcaaata aataatggaa tgcgtctttc aggacgtcgc gaatggattt 815701 tcctttttcc agcacggtat gctgatcaag gtatccgaca cggacatttt ttgaccattc 815761 gacttttccc tcatcaggtt caagctttcc ggtaataata ttcatgaagg ttgattttcc 815821 ttcaccgttt gcgccgatca agccgacgtg ctcgcctttt aacaggcgga aggaaacgtt 815881 attaaaaatg gcccggtccc cgaaaccgtg gcttaaatcc tttacagata aaatactcat 815941 gtttacacct ctatcgttat caaacacgca caatcggcgt gtaatattca cccttttgat 816001 tataaaggag gattcggaat gttgaaaggt ataggaaaga aaaagaaaaa ttgcgttccg 816061 ggcgaggttt tgagatacta tggaatagat ttcaggaatt gaggagaaca aaatgacgca 816121 aacttggcca tttttacata atgcacaatc atttatacaa gagaattgga atgcttccgg 816181 ctttcaaaag ccaacccctg ttcaggagca ggcagcccag ctgatcatgg acggaaagga 816241 tgtcattgca gaatcgccga caggcacagg gaagacgctg gcgtatgcgc tgccggtctt 816301 ggagcggatc aaaccagagc aaaagcatcc gcaggcggtg attttagcgc cttcccgtga 816361 gctggtcatg cagatttttc aggtgattca ggattggaaa gcgggctcag agctgcgcgc 816421 ggcttcctta atcggcgggg cgaatgtgaa gaaacaggtc gaaaagctga agaaacatcc 816481 gcatatcatc gtcggcacgc caggcagggt gtttgaactg attaaagcga agaaactcaa 816541 aatgcatgaa gtgaaaacga tcgtgcttga tgaaacggat cagctcgtcc tgccggagca 816601 tcgcgaaacg atgaagcaaa tcattaaaac aacattaaga gaccgccagc ttctatgttt 816661 ttctgccacg ctcaaaaagg aaacagagga cgtgctccgc gaattggcgc aagagcctga 816721 ggtgttgaag gtgcagcgaa gcaaggcgga ggcagggaaa gtgaagcatc aatacctgat 816781 ttgcgaccag cgcgacaaag tgaagctgct gcaaaagctg tcaaggcttg aaggcatgca 816841 ggcactcgta tttgtgagag acattggcaa cctgagtgta tatgcggaaa aactggcata 816901 tcaccacgtt gaactcggcg ttttgcacag tgaagcgaaa aaaatggagc gagcgaaaat 816961 cattgccaca ttcgaagacg gagagtttcc tcttttattg gcgactgaca ttgccgcacg 817021 cggtttagat attgaaaacc tgccatacgt gattcatgct gatattccag atgaagatgg 817081 ctatgtccac agatcaggac gaacaggccg ggccggaaaa gaaggcaacg tgctgagcct 817141 tgtgacaaaa ttggaggaat ctaagctgaa aaaaatggcg aagaagcttg gtgttgagct 817201 gagtgaagct gtgtatgcag gcggaaaact gaagacgaaa taaaaagaag ggcgaagagc 817261 cctttttttg ttgtaaaata atagaaaaga ttttgcgcgg aggtgggaaa atggcttcaa 817321 tagacaggtt tcaagtaatg caggagccag agctgaaaat ccttgaacac tggtttgaga 817381 atgaggatac cagacggaga atggatggga tgctgctatt agatgagtgg tatgcacgag 817441 taaataaaga taaacacgat actgtcatca tggcgtatga tggacagctg ccggcaggga 817501 tggtcgttat tgagttcgga gaggagcgga catatattgg attgatcgtc aatcctttgt 817561 accggcttaa agggtatgga aaacagatac tgcaaaagct gatgaccgaa cctgatttta 817621 ctagcgtgcg agaatgggtg gcatgcattg aagaagacaa tcgaatcagt ttagcttgct 817681 ttcaagcagc aggattcact ttagaagaca cggaacctga tgaagatggt tttcttacgc 817741 tgattcttcg caactgatct catcgaaaca caaaaggagg gcaaaaagcc ctcccgtttt 817801 catcttcatt cagctcggat cactgacctt gatcagctgt ttccctttat tttctccctt 817861 aaataaaccg agaaacgcgt caggaatgtt ttcgaagcct tctgtgatgg tttcctcgta 817921 atggagttta ccagccttca gccattctgc cagctgtttt gctccctcag aaaaacgatc 817981 ggagtagtcg cttacgataa agccttgcat cagcgacttc gttttaatga gttttgattg 818041 gacacgaggg cccatgtcat ctgcttcgct ttctgcgtta taggaagaaa tggcgccgca 818101 caccggaatg cgggcaaatt cattgagcag attcatcacc gcgtctgaaa tcggtccgcc 818161 gacattgtca aaatacacat cgacaccgtc aggacaagcg ttttgaagcg ctttttggat 818221 atcatccgct gttttgtaat tgatggcttc gtcaaactga agctcctgtt ttaaatagtc 818281 gattttttca tcagagcccg cgatgccgac gactcgcgcg cctttgattt tggcaatttg 818341 cccgactgtt gaaccgacgg ctccggcagc tcctgagaca accacggttt cgccttcctt 818401 cgggcgtccg atgtccagca atccgaagta tgctgttaag ccggtcattc ccaaaatgcc 818461 gagataggcc gaagcgggag caaggcttgt atcaattttt cgcaaggcag actcgctcac 818521 agcggaaaat tcctgccagc tgagatttcc gatgacgata tcgccttttt tcagatgatt 818581 cccgtctgac acaacttcag cgataacccc tccagaaagc gctttatcca aggcgaacgg 818641 ctcaacatat gacttcgtat cctgcatacg gccgcgcata taagggtcaa ccgatacata 818701 aagcgttttg acaagcactt ccccttgctt gggttcagga accggaatgg tttcaaagcg 818761 aaagtcttca tgaacaggaa taccttgtgg acgtcttgct aattgaattt gctgctgaga 818821 tgctgtcatt ttcatcctcc tatcacttgg ttgacaccac tgtaacatgg acaggagagg 818881 aaatacaaaa ggtaagctgg catacaaaaa aggttataga tgagcttatg ctttctacaa 818941 gctcttttgt tttaaaagtt ctctttagtc atttatcatt attagaaaac agaacagaaa 819001 aagagctcct gtacacctag ctaagattgg ctagtgtgta tgtcgattct ttttcatatt 819061 cttgcaagca tctgcgaggg ggagcttagt cgttcacatt ttgctttcgc atcaatctgc 819121 aatagcaaag tctatgcgat ttttttacat cagcaaagat ttgttcaatt ttttcctttt 819181 atgccgagtt tttctgaaac agataattga tggtactcaa ccattttctt ttggtcaata 819241 aagtaatgtt tacttattaa ttaaacacgc gaaaaagcaa acgaaaacat aattaaattt 819301 tatatattta ttaaaagctt atatgtttat ttaccttttt tttgaattgt aattgagaaa 819361 atccatatat tgcggacact aataaaagaa tacctgctga aacataaact aaacgaactc 819421 caaggaaatc tgaaatagcc cctatagcca gaattgaaaa cataaaaatg aactgtacta 819481 aagaagacct tgcagacatt atattaattc gagtttgctc ggttgttatg ttctgaataa 819541 gtgtttcttg tgtaagatct cttaatatat aagccggccc cataaagaga accaaaatta 819601 gagctaagta tgaattactt ataaaaccat atattaaagt taaacttcca tatgagacag 819661 cgccaattaa cataaaatta attaacttat tttgaaatct ctccgacagc ttatatatta 819721 taaatccccc tatcatcgaa cctaaataat atgctccatt aataaatccc caccatgatt 819781 ctcctttatg caagacttcg ttaacgaaag ctaaagagac agatcctatc caaatcattc 819841 ctgcccatga ctcaattaaa tccataataa taattgttct aagtttcttt tggctaaata 819901 aataccgcca accacttact atactcttat tgggagaatt tttttcacgt atgacagaat 819961 tagcgtggcc atgtggtaga caaaataaaa gagaaagaag agatgtaaac aacaaaaaga 820021 tagtaagtat aatggtatat ccctcaccta aaaatgcaat tatgagacca cctaaagacc 820081 agcctacaaa ttgaaaagtt tggtccactg tagataataa tccatttgct tttactcttc 820141 tatcaggaga gattatttcc cctataattg cactttttaa aggtgagaac catccattaa 820201 aaaaggaaat acagctaata ataataaaga ctaaaatgag agtttgatta gagtaagttc 820261 ttaataaagc atagaacaaa catattaata acagcatttg tatcaattga gaaataatta 820321 ttgtaagagg cagttttaat cgaattgtta ttaacggtaa tatagcactt ccaaaaatac 820381 gaaaaataat acttattaat gtcaccatag aggcgatggt tgtcgaattg gtcattttaa 820441 acaaaaacga aatcactacc atagtatata gagaaaaacc taaatttgta gtggtctggc 820501 taaataaaat agaataataa cctttactca tatgtatcct cccttggaat aatttttctc 820561 ggtaaagagc ttaaacatat ttaaacacct taaaacaaca aaagtaaaga aaaaatttcc 820621 ttgtaaacta tttactttta ttctatttat tgttattgtt tatttaagtt ctctgactat 820681 tctatcaata ttcagggaac cacatatctt attaaagggg ggaaaaccat gagaaaatta 820741 agaaaaaact ggagaaaatc gattgttagc ccggttcttt atactaatga aaaatggtaa 820801 acacttaggg aatagcattt aatgctattc cttatttcaa caaacaaatc gggaggttat 820861 cgtaatttga ctctattaat gcaagatcat aaatcaattt acaataaaga tatagaaata 820921 ttaattgaag ttgaagaact tattacttct gttccagaaa ataaaaaaaa tgattttaag 820981 agtttaatcg ataatagaat tatgactcta ctaaataaaa ttcaacaccc tgtagcagcg 821041 gaaaatgtgt ttgggatgtg tattgcttat ccgaatactt acataaggta tagattaatt 821101 gatttcgttg aaaaatgggt accttatttc tctgctgtag aaactataat caatctaacc 821161 caggatccgg atgatttagt ttcttttaaa gctatggatg tctgtgcaaa tcataaaatt 821221 gaagaatctg tagcatattt gtcttcgatt attgatgatg tccgggagag tataagctac 821281 cctaaaaaac ctgtgggatt aggggcccaa aaagtattaa gtacattatt agatatattc 821341 ggtgttgaaa aacatgaaga gctagtaatg ctaaaaaatt attttgatca aaatggtata 821401 cttcctaata actttgactt tgaagaaaaa attcctcaaa gtctaataga ggaattcgaa 821461 aaaacagaag aagatgggat gattttaatt ccgggtggct tttttgaatt cggtttaaat 821521 gaaaatgaaa ttcctgacaa aacatttaat tggaaagatg ctgttcctag acaaaaagta 821581 tggttacctc cattttttat cgataagtat cctgttacaa ataaagatta tgatatcttt 821641 accgagttca tagaggaaaa tgggcatata ttctgtcatc ctaatgaacc gcagaataaa 821701 caacatagaa gaaatacata ttgggatgat aggtatttag ataatcatcc cgttacaggt 821761 atagattttt atgatgcatt tgcttacgca agatataagg ggaaagaatt gccaaccgag 821821 tttcaatggg aaaaagctgc tcgaggcgaa aagggtaatg tctggccttg gggagataaa 821881 tttgatcctg caaaggttca atatgctgga agtctttata atgaacccat tacttcttta 821941 aagtcctgga gagaaaattt attaaaagct catgctgata aagaattaaa tcatttaaca 822001 agtgatattt ttgaacaaaa tggtgaaagt ccctatggag tatgcggtat gatcggcgga 822061 acatgggagt ggactagaag tgagcttaaa acaaagagag ctttccaccc tatttttgag 822121 aatgtaccat ttaatagtgt taactcattt gccgttctta aaggaggatc attcttctct 822181 catccaggct taatgttccc ttcttttaga gcaaaagata ttcctttctg tcgacacaat 822241 gaaatgggga ttagatgcgt aaagaatatt ccagtatata aaattagaga atcaattaat 822301 gggccaatta ctaataaagc aatttattaa tcattctagg ttagagactt gataaaagta 822361 tactaacatt gtgtagtaat gttcagcttg tagaaaaaac aatgtttttt ctacaagatt 822421 ttattttaaa tgcttttcaa aattatcagg gattgagaat cagaaaaaga gccattaagc 822481 tcgatcttag ctaggtatta cgatcttctg tatattattg tgagaaatat agaagattca 822541 gttagttagc atttcgattt taagctgagc ctgcaatagc aaagcatctg ttttgattat 822601 tctttttctg atacataagc taattttgtc gcttttcttt tttgtctttt cacgcatttc 822661 gaggatgact tactataatt ctttcagctt ttctatgtgt taagattcga atagatgaaa 822721 taactttaac aagttggtca ataagaacag atttaacttt atgttaaaag agtatctcgt 822781 atagaacata agaagaatga cgagtttttt aagattatca tcaattatgt gagaataaaa 822841 tattataagg gaaaatgaag gctgtcacgt ttctcgacag ccctagggaa ttcctctcct 822901 tttcatttcg cccgtaattt cgggcacagt cccgtcggca ggcacattgg cttctggtcg 822961 atcgggcttc tcatgatgca gcattccaag ccgaagactt cacggaaaaa tggctgggtg 823021 aacacatctt ccggtgttcc ggcgttgtat atttttccgt ccagcacact gatcagatag 823081 tcagcatatt gagcggcttg gtttaaatca tggagcacca tgacaacggt gcggccatgg 823141 tcgcggttca gctttttcag cagttcaagc acttcaatct gatgtgagat gtctaaatac 823201 gtggtcggct catcaagcaa aagcaaatca gtgccttgcg caagtgccat ggaaatccag 823261 gctctttgtc tttggccgcc tgagagggca tcaagtgtcc gatccttcag ttcaatcatg 823321 cccgttgctt ccagcgccca ctctaccatg tcatgatcct cttgggtatg cttggataac 823381 agctttttgt gaggatgtct gccaaaatag cataattcct ctaccgtcaa tccttcagga 823441 gcctgaggag attgtggaag aatggccagt ttttttgcga cttcttttga tggctggcgg 823501 tggatgtctt ttccttctag tagcactgta ccgctttttg gggccatcag cctggcgagc 823561 gatttgagga ttgttgattt accgcagcca ttagcgccga tgagcgcagt gatttttcct 823621 tcttctatct ttaagtcgac tccgtcaata atcactgtac tgtcatatga aagagtgagc 823681 tggtctgcag ccagttttcc catggtatcc tctccctact gtttcctcgc ttcgaatttc 823741 aataaatata agaaataagg cgcgccgatc acggctgtca gtattccggc aggtatttca 823801 accggaggca tgatgccgcg ccctaacgta tctgcaatta ataatataat agcaccaatc 823861 aatgccgatg caggcagtaa atatttagct ttttctccgg taagccgtct ggcgatatgc 823921 ggagcaagca agccgataaa accgattgag ccgacgacgg ctacacagct tcccgccagc 823981 gccaccgcgg tgaaaatcag gatgaatctc agccggtttg cgttttctcc gagaccctgt 824041 gcaagctcat ccccgagtga cataagatcc agcttcggta tgagtatgca gacgatcgga 824101 aaaagaatca aaagccatgg cgcaagcagc ttgacttctt cccagtttct tccccagagg 824161 cttcctgtca gccaaatgag tgcagcattc acgtcgcctg gaaacttgac catcatatat 824221 tgcattccgg cgtggcagac cgcgcctaaa gcaatgcctg ataaagccag tgaagagggc 824281 tgaatgctct tttttcgggc tatcattaat aatagtacag caataatggc ggctccggca 824341 aatgcggaga acggaagcac gtataccggc gactcaggaa agatgagaat cacagccatc 824401 gccgcaagtc cggagccttt tgaaatgccg acaacgtccg gggaagcgag cggatttcgg 824461 atcacaccct gtaaaatcgc tccggcagcg gcaagtccag cacctgccaa aatcgctaat 824521 ataatgcggg gaaggcgata ttgctggatg ataaattcaa aggaatgatc cagtcccagc 824581 agattcgtca ctaccgcatc aggtgaaatg tataatgcac cgattccaat gctgatgacg 824641 gacagaacga ttaaaatcac ggccaatatg agtatcgcca gtaaggggcg tttttgtttt 824701 ctggttgttt tcttcatttc aggtttcgcc ctttccttgc caaatataag aaaaacggcg 824761 ttccgataat cgcggtgaca atgccgaccg gtgattcata aggaaatgca atccatctgg 824821 ccagaacatc tgcgtacacc agcaaaatgg caccgaacag tgccgaaaac ggaagcacgt 824881 attgataatg ttctccgatc agcttgcgga caatatgcgg gacgagcagc ccgacaaagc 824941 caatcggccc ggcgacggct acggaagcgc cggaaagaat taaaataatc aaactgatca 825001 gaatcctgat gccgttcata ttttgtccaa gcccttttgc tgtttcgtct ccgagaccga 825061 gaacagaaac agaaccggaa aatacgaggg caagcccgat gccaatgaca gaaaaaggag 825121 cgatggttat gacgtcctgc cagttgctgc cgtcgattgc gcctgtcatc cagtacagaa 825181 catcctcacc tgactcattt aaaataatga tggcctgtgt catagaggag aggaacaagt 825241 gcacggccat tcctgacagc gccagcttga caggcgtcat tccgccggat gaggcaatca 825301 tatacacaat cgcgccgcct gctgccgcac ccgcaaaagc gaatataaca gatgaatagg 825361 gcgatgccgg cagaatgacg agagaagcaa caacaaaaag cgatgcaccc gcattcacac 825421 cgaaaatttg gggtgaagcc agaggatttc tggtcatagc ctgcatcagc gcccctgcta 825481 cagctaggct ggcgccgaca aaaacgccga ttaatgtgcg gggaaggcga agagtagaga 825541 tgatgagctg ttcctttgaa ccgtcccata caaaaagata tttcaatgaa tctatgatgc 825601 tgatgtctga ggctcctact gaaagattca gcccaagccc aaatataaaa ataatcagtg 825661 caatgataaa catcatcagt cttgatgatg agcgccgttt ggctgaatga tacaacagtc 825721 tcacttcctt actgcgtctg gttgcaaaaa cgaagaagca aggattcccc tcgcttctca 825781 tttgtcctat ttattataca cttttttaag cacatctttg gcgcttgttt cactagactt 825841 gatgcctctg aatcttgtcc aagtgtcacg gtccgcatca tagacttgtc catttttcac 825901 cgctttgaga tttttccaga gcgggttcgt tttccactca tctacaatgg ttttgccttc 825961 gttggctgag atgaacaaaa tatcaggatc gattttgctc aattgctcaa ggctgacctc 826021 ttgataggcg ttatctgact tcacagcgtg tgtaaagcct agcattttaa agatttctcc 826081 gtcataggat gatgatgtat gaagctggaa ggaatccgct cttgcaacgc cgagaacgat 826141 gttgcggttt tcatctttcg gaagttcggc ttttagatcg ttgatgactt ttttgtgctc 826201 ggcaagcttt tcttttcctt catcttcttt atttaatgct ttagcaatgg tcgtaaagct 826261 gtcgatcgtt tcgtcatatg tcgcttcacg gctttttaat tcaatcgtcg gggcgatttt 826321 tttcagctgt ttataaatgt ttttatggcg ctcagcgtca gcgatgatta aatcaggctt 826381 caaggaactg atgacctcaa gattgggttc gctgcgtgtg cctacagatg tgtaatcaat 826441 ggagctgccg acaagctttt taatcatatc ttttttgttg tcatctgcga tgcccaccgg 826501 cgtaatgccg agattgtgaa cggcatccaa gaatgaaagc tcaagcacaa ccacccgctt 826561 aggtgtgccg cttactgtcg tttttccttc ttcgtcatgg atcactctgg aatccttaga 826621 ctcgcttttg ccgcttccgt tgttattctg gcttgatgaa cagccggata caatgaggca 826681 ggcgagcaat aaaacactca tgatggcaat caacttgtta gaataggtgc gcatgtcatt 826741 cttccttttt tcagatttag taatgagaat cattatcaca tgtaacacta taatagcatg 826801 gcttatcatg tcaatatttt tttagtaaag aaagctgcgt ttttactgct ttctcatgaa 826861 agcatcatca gacacaaata agtggtatgc agcgttaccg tgtcttcgag acaaaaacgc 826921 atgggcgttg gctttagagg tttcgaacat atcagcagtg acataaggaa ggagagtgct 826981 gagataaccg gacaatttct tttctatttc atctgttagt gcaaattcaa tgtcgccgat 827041 attcatgata atcgagaaaa caaagtcgat atcgatatga aaatgttcct cggcaaaaac 827101 cgcaagctcg tgaattcctg gtgaacatcc ggcacgctta tggaaaatct gtttgactaa 827161 atcactcaca atccaagcat tgtattgctg ttctggtgaa aagtattgca ttagacatac 827221 ctcctgctcg tacggataaa ggcagcgttt catggtcgtg tgctccgtgc agcggcttct 827281 ccttaatttt gatttttctg aaaataggtc ccgttcctat cactttacca tggacggaaa 827341 acaaatagct actaccattc ctcctgtttt tctcttcaat gttctggaat ctgtttcagg 827401 tacagacgat cgggtatgaa agaaatatag aaaacatgaa ggaggaatat cgacatgaaa 827461 ccagttgtaa aagagtatac aaatgacgaa cagctcatga aagatgtaga ggaattgcag 827521 aaaatgggtg ttgcgaaaga ggatgtatac gtcttagctc acgacgatga cagaacggaa 827581 cgcctggctg acaacacgaa cgccaacacg atcggagcca aagaaacagg tttcaagcac 827641 gcggtgggaa atatcttcaa taaaaaagga gacgagctcc gcaataaaat tcacgaaatc 827701 ggtttttctg aagatgaagc cgctcaattt gaaaaacgct tagatgaagg aaaagtgctt 827761 ctctttgtga cagataacga aaaagtgaaa gcttgggcat aaagcaagga aaaaaccaaa 827821 aggccaatgt cggccttttg gtttttttgc ggtctttgcg gtgggatttt gcagaatgcc 827881 gcaataggat agcggaacat tttcggttct gaatgtccct caatttgcta ttatattttt 827941 gtgataaatt ggaataaaat ctcacaaaat agaaaatggg ggtacatagt ggatgaaaaa 828001 agtgatgtta gctacggctt tgtttttagg attgactcca gctggcgcga acgcagctga 828061 tttaggccac cagacgttgg gatccaatga tggctggggc gcgtactcga ccggcacgac 828121 aggcggatca aaagcatcct cctcaaatgt gtataccgtc agcaacagaa accagcttgt 828181 ctcggcatta gggaaggaaa cgaacacaac gccaaaaatc atttatatca agggaacgat 828241 tgacatgaac gtggatgaca atctgaagcc gcttggccta aatgactata aagatccgga 828301 gtatgatttg gacaaatatt tgaaagccta tgatcctagc acatggggca aaaaagagcc 828361 gtcgggaaca caagaagaag cgagagcacg ctctcagaaa aaccaaaaag cacgggtcat 828421 ggtggatatc cctgcaaaca cgacgatcgt cggttcaggg actaacgcta aagtcgtggg 828481 aggaaacttc caaatcaaga gtgataacgt cattattcgc aacattgaat tccaggatgc 828541 ctatgactat tttccgcaat gggatccgac tgacggaagc tcagggaact ggaactcaca 828601 atacgacaac atcacgataa acggcggcac acacatctgg attgatcact gtacatttaa 828661 tgacggttcg cgtccggaca gcacatcacc gaaatattat ggaagaaaat atcagcacca 828721 tgacggccaa acggatgctt ccaacggtgc taactatatc acgatgtcct acaactatta 828781 tcacgatcat gataaaagct ccattttcgg atcaagtgac agcaaaacct ccgatgacgg 828841 caaattaaaa attacgctgc atcataaccg ctataaaaat attgtccagc gcgcgccgag 828901 agtccgcttc gggcaagtgc acgtatacaa caactattat gaaggaagca caagctcttc 828961 aagttatcct tttagctatg catggggaat cggaaagtca tctaaaatct atgcccaaaa 829021 caatgtcatt gacgtaccgg gactgtcagc tgctaaaacg atcagcgtat tcagcggggg 829081 aacggcttta tatgactccg gcacgttgct gaacggcaca cagatcaacg catcggctgc 829141 aaacgggctg agctcttctg tcggctggac gccgtctctg catggatcga ttgatgcttc 829201 tgctaatgtg aaatcaaatg ttataaatca agcgggtgcg ggtaaattaa attaagaaag 829261 tgaaaaacac aaagggtgct aacctttgtg ttttttaatt aattaaaatg tttattaact 829321 tagttaagga gtagaatgga aaaggggatc ggaaaacaag tatataggag gagacctatt 829381 tatggcttca gaaaaagacg caggaaaaca gtcagcagta aagcttgttc cattgcttat 829441 tactgtcgct gtgggactaa tcatctggtt tattcccgct ccgtccggac ttgaacctaa 829501 agcttggcat ttgtttgcga tttttgtcgc aacaattatc ggctttatct ccaagccctt 829561 gccaatgggt gcaattgcaa tttttgcatt ggcggttact gcactaactg gaacactatc 829621 aattgaggat acattaagcg gattcgggaa taagaccatt tggcttatcg ttatcgcatt 829681 ctttatttcc cggggattta tcaaaaccgg tctcggtgcg agaatttcgt atgtattcgt 829741 tcagaaattc ggaaaaaaaa cccttggact ttcttattca ctgctattca gtgatttaat 829801 actttcacct gctattccaa gtaatacggc gcgtgcagga ggcattatat ttcctattat 829861 cagatcatta tccgaaacat tcggatcaag cccggcaaat ggaacagaga gaaaaatcgg 829921 tgcattctta ttaaaaaccg gttttcaggg gaatctgatc acatctgcta tgttcctgac 829981 agcgatggcg gcgaacccgc tgattgccaa gctggcccat gatgtcgcag gggtggactt 830041 aacatggaca agctgggcaa ttgccgcgat tgtaccggga cttgtaagct taatcatcac 830101 gccgcttgtg atttacaaac tgtatccgcc ggaaatcaaa gaaacaccgg atgcggcgaa 830161 aatcgcaaca gaaaaactga aagaaatggg accgttcaaa aaatcggagc tttccatggt 830221 tatcgtgttt cttttggtgc ttgtgctgtg gatttttggc ggcagcttca acatcgacgc 830281 taccacaacc gcattgatcg gtttggccgt tctcttatta tcacaagttc tgacttggga 830341 tgatatcaag aaagaacagg gcgcttggga tacgctcact tggtttgcgg cgcttgtcat 830401 gctcgccaac ttcttgaatg aattaggcat ggtgtcttgg ttcagtaatg ccatgaaatc 830461 atccgtatca gggttctctt ggattgtggc attcatcatt ttaattgttg tgtattatta 830521 ctctcactat ttctttgcaa gtgcgacagc ccacatcagt gcgatgtatt cagcattttt 830581 ggctgtcgtc gtggcagcgg gcgcaccgcc gcttttagca gcgctgagcc tcgcgttcat 830641 cagcaacctg ttcgggtcaa cgactcacta cggttctgga gcggctccgg tcttcttcgg 830701 agcaggctac atcccgcaag gcaaatggtg gtccatcgga tttatcctgt cgattgttca 830761 tatcatcgta tggcttgtga tcggcggatt atggtggaaa gtactaggaa tatggtagaa 830821 agaaaaaggc agacgcggtc tgcctttttt tattttcact ccttcgtaag aaaatggatt 830881 ttgaaaaatg agaaaattcc ctgtgaaaaa tggtatgatc taggtagaaa ggacggctgg 830941 tgctgtggtg aaaaagcggt tccatttttc cctgcaaaca aaaataatgg ggctgattgc 831001 ggctctgctg gtctttgtca ttggtgtgct gaccattacg ttagccgttc agcatacaca 831061 gggagaacgg agacaggcag agcagctggc ggttcaaacg gcgagaacca tttcctatat 831121 gccgccggtt aaagagctca ttgagagaaa agacggacat gcggctcaga cgcaagaggt 831181 cattgaacaa atgaaagaac agactggtgc gtttgccatt tatgttttga acgaaaaagg 831241 agacattcgc agcgcctctg gaaaaagcgg attaaagaaa ctggagcgca gcagagaaat 831301 tttgtttggc ggttcgcatg tttctgaaac aaaagcggat ggacgaagag tgatcagagg 831361 gagcgcgccg attataaaag aacagaaggg atacagccaa gtgatcggca gcgtgtctgt 831421 tgattttctg caaacggaga cagagcaaag catcaaaaag catttgagaa atttgagtgt 831481 gattgctgtg cttgtactgc tgctcggatt tattggcgcc gccgtgctgg cgaaaagcat 831541 cagaaaggat acgctcgggc ttgaaccgca tgagatcgcg gctctatatc gtgagaggaa 831601 cgcaatgctt ttcgcgattc gagaagggat tattgccacc aatcgtgaag gcgtcgtcac 831661 catgatgaac gtatcggcgg ccgagatgct gaagctgccc gagcctgtga tccatcttcc 831721 tatagatgac gtcatgccgg gagcagggct gatgtctgtg cttgaaaaag gagaaatgct 831781 gccgaaccag gaagtaagcg tcaacgatca agtgtttatt atcaatacga aagtgatgaa 831841 tcaaggcggg caggcgtatg ggattgtcgt cagcttcagg gagaaaacag agctgaagaa 831901 gctgatcgac acattgacag aggttcgcaa atattcagag gatctcaggg cgcagactca 831961 tgaattttca aataagcttt atgcgatttt agggctgctt gagcttgggg agtatgatga 832021 agccattgat ctgattaaag aggaatatgc gatacaaaat gaacagcatg atcttttatt 832081 ccataacatc cattcgcagc aggtgcaggc cattttgtta gggaaaataa gcaaggcatc 832141 ggaaaagaag gtcaagctgg tgattgatga gaacagctca ctcgcgcctc ttcctgcgca 832201 tatcggcttg tcccatctta ttacgattat tggcaattta attgataacg ctttcgaagc 832261 tgtagcggag caaagcgtga aggaagtttt gttttttatc acggatatgg gccatgacat 832321 tgtcattgaa gtatcagaca cagggcccgg tgtgccgcca gagaaaatag aagctgtgtt 832381 tgagagaggc tattcttcaa aggggatgag gagaggctac ggtctggcca atgtgaaaga 832441 ctcagtgcgt gaactgggcg gctggatcga actggcgaat caaaaaactg gcggggcggt 832501 attcactgta tttataccga aggagaaaca aagggggaat ccatttgatt cacatcgcga 832561 ttgcggagga tgattttcga gttgcgcaaa tccatgagag attgattaaa cagcttgatg 832621 gattcaagat tatcggcaag gcggctaacg caaaagagac attggcgctt ttgaaggaac 832681 acaaggctga tttgcttctg ctggatattt atatgccgga cgagcttggg accgcgttga 832741 ttcctgatat acgaagccga tttcctgaag tggacattat gattatcaca gcggcaacag 832801 aaacccgtca tttgcaggaa gcgctaaggg cgggaattgc ccactatttg atcaaacccg 832861 taacagctga caagttcagg caggtgctgc ttcagtataa agaaaaaagg aagctgctca 832921 tgtctcagcc ggaggtcagc caatccatga tcgaccatat ttttgggaac ggtgtgaaga 832981 cagctttgcc ggcagaggat ttgccgactg gcattaattc gattacactg cgaaaaatta 833041 aggaagcgct tcagactgcg tcagaaggat tgacagcgga ggaacttggg gaaaaaatgg 833101 gggcgtcacg aacaactgcc cgccgttatg ccgagtacct tgtgtcaaag gaagaagcaa 833161 gagccgagct tgaatacggg attatcggca ggccggagag aaaatattat ttggcggcgg 833221 attagatatg aaaaaatcta taatcctatt gaatattcta ttgatcttta tgcagggtga 833281 tatcaggcag gcggctgcgc cgcgcctgcc ggacgggccg atagaaattg tcgtccctgc 833341 cgaaccttct ggcggctggg atgtcacagc gcaggcgatc caatcagttt tgaggcagaa 833401 gcagatcgtg aaggatgatg ttcatatcgt ctataaatcc ggcggcgggg gagagaaagg 833461 ctggaaatat gtcaacaaaa gcagcaaaca aaccatcagc atgacgtcca gcctaatatt 833521 gagcaatgat cttctcgggc aaagcaaatt aaaaatgtcc gattttacgc cgctcgccat 833581 tctctccaag gaatggcaga cggttgcatt gccaaaagga tcagcgttaa caaatggcaa 833641 ggatgtgctg aatgagatca acatgcatcc cggcaaggtg agaatcggct ttgccccggg 833701 gtttggcaat gatgatcagc tctcgttcgt cagagcggca gatatgtacg gcattgaccc 833761 gtttgacatt caattctcac agtatgacag cagcgaacag ctcattcagg cgctgatcag 833821 acatgagata gaagcggctt ccatgacact ttctgaagcg aaaccatatg aacgaaacgg 833881 cgatatcacg ttagccgctg taacgtctga taaaagactt cccggttttc caaatgtacc 833941 gacgtggaag gagcagggaa tcccgtttgt tttttctcat tggagaggga ttttgggccc 834001 gaaaaatatg tctgaggaag agatttctta ctgggatcaa gcgctaaaga aggtcacctc 834061 ctcacctgaa tggaagcgga aaataaacga acaggactgg gaaagctttt atttaaacag 834121 cagggaaacg aaacggtttt tagaagagca atctgctttt tatcaaagca tcatgacagg 834181 aaattaaaat cccgacatcc cgggattttt ttcatgccga aaattgatca aaaagaacaa 834241 aacggtttta aaaaattaaa aatacaaaaa aaccaaatta tttacttgcg gttggttttc 834301 ccatacgatg gcaaaaaggc aagacaaaaa ggggagtaag ggagaaaaaa atgtaagcgg 834361 attcatttaa gggggaatgg atgtgttagc aatcttaggc tttctcatga tgcttgtgtt 834421 tatggcattg atcatgacaa aacggctttc tgttttaaca gcattagttt tgacgccgat 834481 tgtgtttgcg cttatcgccg gatttggatt tactgaagtt ggggacatga tgatttcggg 834541 gattcagcaa gtcgcgccga ctgcggtcat gattatgttt gcgatcttat attttggaat 834601 tatgattgat acaggcctgt ttgatccaat ggttggcaaa attttaagca tggtcaaagg 834661 agacccttta aaaattgttg tcgggacagc ggttcttaca atgctcgtcg ccttggacgg 834721 agatggctcg acaacgtaca tgattacgac aagcgccatg cttccgctct atttgctgct 834781 aggcatccgg ccaattatct tggcaggaat cgcgggagtc ggcatgggaa tcatgaacac 834841 gattccatgg ggaggtgcga cgccgagggc ggcgagtgcg ctgggggttg atccagctga 834901 gcttacaggg ccgatgattc ctgtcattgc aagcgggatg ctttgtatgg tggcagttgc 834961 gtatgtgctt ggaaaagcgg aacgaaagcg ccttggtgtg attgaactga aacagccagc 835021 caatgccaat gaaccggctg ctgcggttga agatgagtgg aagcggccga agctttggtg 835081 gttcaattta ttgttaacgc tttctttaat aggatgttta gtatcgggta aagtcagttt 835141 aaccgtactg tttgtcattg cgttttgtat tgcgctgatt gtgaattatc ccaatctcga 835201 gcatcagaga cagcgcatcg cggcgcattc cagcaacgtg ctggctatcg gttcaatgat 835261 ttttgctgcg ggggtgttca cggggatttt gacaggcacg aaaatggttg atgaaatggc 835321 gatctcgctc gtgtccatga taccggaaca aatgggcgga ttgatcccgg cgattgttgc 835381 cttaacaagc ggcattttca catttttgat gccgaatgac gcgtatttct acggggtgct 835441 gccgatttta tcagaaacag ctgtcgcata cggtgtggat aaagtggaaa ttgccagagc 835501 ctctattatc ggccagccga ttcatatgct gagtccgctt gtgccatcca ctcatttgct 835561 tgtcggactc gtcggagttt ctattgatga ccatcaaaaa ttcgcattga aatgggcggt 835621 tctcgcagtg atcgtcatga cggctatcgc tctattgatc ggtgcgatct ctatttccgt 835681 atgataattc aggcgtaatg acacacacta acggcataca acattccgga ggtgtcatta 835741 tgagtgatcc ttatatgccg ctgacttcag tcagaagcgg agcggggttc gaagcggcaa 835801 aaggggtgca cggcctgact gtgcaaattg cgaatgtcta ttttattcag ctgccttctg 835861 aacctcactc atttgtttta attgatgccg gcatgcccca atcagccggc gtgattgtca 835921 atgaagccaa acaaagattc ggtgaagggt ttcagctgaa ggcgattatc ctcacacacg 835981 ggcactttga ccatattggg gcaatcgaag agatccttga gcattgggat gtgcctgttt 836041 atatccattc tcgggaaatg ccttatgtaa caggtaaaga ggattatcct ccggctcgtc 836101 ctgacagcaa gagcgggctg gtcgctaagc tgtcgccgct gtttccgcgg cactctatcg 836161 atatttcctc acatgtccag gcactgccgg aagacggttc agttcctttt cttgacgagt 836221 ggatgtggat cgcgacacca ggacacacgc cgggccatat ttcgttattc cgcgatgacg 836281 gccgcgtgct tgtggcaggt gatgctgtta ttacagtgga acaggagaaa atggctgacg 836341 tcttgataca aaaacaggag cttcacgggc cgccggctta tttcacgcct gacacagaga 836401 cggccgctga gtccattcta aagctggccg gtcttgaacc ggaagcgtta ttgaccgggc 836461 acggcatacc gatgaccggc aaaaactttc gaagtgactt aactgaattg gcaaatcggt 836521 tatcgtctat ttgacacccg caccacgcgg gtgtttttta ttgttttcca ggaagttgca 836581 gaaaaatcat ttgtcttgcc gcttaaaaac gatacaatga aaagcatgaa gtgatgtgaa 836641 ggggagagtt tgttggaaga aaaagaaata ctctggaacg aagcgaaagc gtttattgcc 836701 gcatgctatc aggaattggg aaaggaggag gaagtgaaag accgtctcgc ggacattaaa 836761 agtgaaattg acctgaccgg aagctatgta catacgaagg aagagctgga gcacggagcg 836821 aaaatggctt ggagaaacag caaccgctgc atcggcagat tgttctggaa ttcgctgaat 836881 gttatcgaca gacgagacgt ccggacgaag gaggaagtgc gtgatgccct ctttcaccat 836941 attgaaaccg ccaccaataa cgggaaaatc agaccgacca ttacgatttt ccctccggaa 837001 gagaagggtg aaaagcaagt cgagatctgg aatcatcagc tgatccggta cgctggatat 837061 gagtcagacg gagaaagaat cggcgacccg gcttcctgtt ccctgacagc agcctgcgaa 837121 gagctcggct ggcgcggaga gcgaacggat tttgacctgc tgccgctcat ttttcgcatg 837181 aaaggggacg agcagcctgt ctggtatgag ctgccgcgtt cacttgtgat tgaggttcca 837241 atcacacatc cggacatcga ggcgttttct gatttggagc tgaagtggta cggcgtgcct 837301 attatttctg atatgaagct tgaggtcggg ggcattcatt ataatgccgc gccatttaac 837361 ggctggtata tgggcacgga gatcggagcg agaaacctcg cagatgaaaa gcggtacgac 837421 aagctcaaaa aagtagcgtc cgtgatcggc atcgccgctg attacaatac ggatttatgg 837481 aaggatcaag cgctagttga attgaataaa gctgtgctgc actcgtataa aaagcagggt 837541 gtcagcatcg ttgaccatca tacagcggca agccagttta aacggtttga agaacaggag 837601 gaagaagcgg gcagaaagct gacgggggac tggacgtggc tgattccgcc aatttcaccc 837661 gctgccactc atatcttcca ccgctcctat gataactcaa tcgttaagcc gaactatttt 837721 tatcaagata agccttatga gtaaacaata gaaaatcgat gatggccttc aaggctgcgg 837781 gattcagtca cagagatgtc ggtaaccttt gagaaagggc ttccgttctt tacagcctca 837841 acaaacgatt gcagggcgtt ttccggaccc tctgccaaaa tctcgacacg cccgtcatca 837901 cggtttttga cccagccggc cagttttcgc ttatcagctt ccatttgaac aaaatagcga 837961 aagcccacac cttgaacccg gccgtctaca atgattcggt attgaagcat gtaaaaacca 838021 ccttttcttt ttatgataat caatcatttt acaacctgta aaggggatgt gtttgtatga 838081 aacaagagcg ctattcagtt ctttctctta atctgggaaa accgcagacg cttgaatatg 838141 acggaaagaa aatcgaaacc ggcatcatga agcggccggc taaatcagcc gtcatgctgt 838201 atcgggagaa ttttgaagga gacggacagg cggacctcgt caaccacggc ggacctgata 838261 aggctgtctg tgtctacccg gcggagcatt atccgttttg ggaagagttc ctctcaagac 838321 cgctgtcaaa tgccgcattt ggagaaaatc tgacggtcgc gggcctgact gaggagaatg 838381 tttgcatcgg ggatgtgttc agacttgatg aagctgttgt tcaggtcagc cagccgcgcc 838441 agccgtgtgt aaagctggcg aaaaagtttg gtgtaaaaga aatggtgctg aaggtccagc 838501 aaaccggcta tacagggttt tattttcgcg tgctggagga gggcagggtg tctcccggcg 838561 cgaaccttga attgctgtcc agaggagaga aaggcatatc cgtccagttc gcgaaccgca 838621 tcaactacca tgatgcaaaa aatctcaccg ccattgaacg gattttaagt gaggctgcac 838681 tatcggaaag ctggagagcg tcctttatga aaaaaaagga caggctgctg ccggttgaat 838741 agaaaaaagc cgcgcatatc aacgtgcgcg gctttgccat atttaagatt gttttttctt 838801 tgattcaagc aggttggcaa gaaaataggt tttatagctt tgaagctttc ttccttcatg 838861 gtgcgtgatc ccctgctttt ttagttctgc cacataccag cctttactgc cgtaatgcat 838921 gtcagaaaac tcctttccct atctgatttc gaaacgattg gcattgtaac atctataaaa 838981 agatgctgaa aagagatgcg gggaaaactg agcctttcgc actagatgta cgaatgttct 839041 tctgaatgta tatgcggagc aaaagccgaa tatgatttaa tggccggtta gtttgatcat 839101 gacaacgcca aatgtcataa tggcgaaaac aatgccgata tatgtgagca tcccgttttt 839161 tttcttaacg ccgtaaacgg tcataatgat gccttcaatg aaaaaaatga tgccgaaaat 839221 aataaaccac atgcagataa aggctccttt cacagacata atagtagtgt agcatatctg 839281 aaagagccgg gctgtgacaa tatcaagaaa gccgggcgca tatcgcccgg ctcatgtttt 839341 attgtttatc aaccaatttg accagaagct gtgccaaatg ttctttctca tcttcgtctg 839401 caacgctcca aagctcttgc agcagcattt cttcaccgtt ttgcggctct tcatgctttg 839461 cgaggtagtc tcccaggatc gcagcgcttt ttacaagctt gccgtcatcc aatcccagct 839521 ttttgcctcg gttgacttgt tttttcaggt agcctttaaa ttcctcaaag tcttttaaaa 839581 tgtcttcttt tattgtgcca tgcatcgcgt tcatttcgtt ttcaatttgg attttttctt 839641 gatctctgtt cattgcaaga cctcctcgta cagaataatg atgctttacc tgcaattgga 839701 ggaggttaaa cctgccggaa gcccggaatg tgttttacag tttcgtcagg ataatcggtt 839761 catcttttgt gatgacgatc gtgtgttcaa cttgggcaac catgctttta tccggcgtct 839821 tgaacgtcca gccgtctcca gcttcaacaa tcgtttctgc tttcgttgaa ataaacggtt 839881 caagcgcgat gactgtgcca tttttgaaca gcgcattatc aaacggatca taatagttca 839941 tgatgtggtt cggcgcttca tgcaggcttc ggccgattcc gtggccggtc agggttttga 840001 tgacggtaaa gccttgagag cgtgcttcat gataaacggc tcttccgatc tggttttggc 840061 gcttgcccgc ttttgcctgc tgaagcccct tttgaaaagc gttttccgcg cattggcaaa 840121 gcttatgaag gcgttcttct ccttcaccga gcacaaatga gatgcctgtg tcggaataga 840181 agccgccaaa ttcagcggag atgtcgatgt tgacaaggtc ccctgctttt aaaattttgg 840241 atgtgcttgg tatgccgtga gccacttcat catttacgct gatacatgtc acacctggaa 840301 aatcgtattc cttctcagga gctgaaacgg cgccgtgctc atcaagcaca gcttttccga 840361 taaggtcaag gtcttttgtg ctcatgccgg gctctgcctt ccgcttcatt tcttcacgcg 840421 caagcgcgac gattcttccg atttttttca ggccttctaa ttcttgatcg tttgttacaa 840481 tcatctgtca ttcccgcttt ctttttaaat aatctagatt aagcttacca caactgtctt 840541 aaaaatagga aacacacgga cctgggaaaa aagaaatacc cccgggaaaa ttggtataga 840601 tcactagata tcttatatgg tatatttgaa aaaaaagggt atgaggggga tgggtatgct 840661 ttcattttta caaaaactcg ggaagtcatt tatgctcccg attgcggttc tgcctgcggt 840721 tggaattatc cttgcgcttg gcagagagga tgtatttaat atcccgtttg tctatcaggc 840781 ggggacggcg gtttttgatc atctgccgct tatttttgcg atcggtattg ccatcggcat 840841 ttcaaaagac agcaatgggg cagcgggttt atcaggggcg atatcgtatc tgatgcttga 840901 cgcggcaaca aagacaattg ataaaacaaa taacatggcg gtgtttgggg gaattattgc 840961 cggtttaatt gccggttaca cctataaccg cttcaaggat accaagctgc ctgaatatct 841021 cgggttcttc agtggcagac ggcttgtgcc gattttaaca gccattatta cgatcatttt 841081 agcgggcata ttcggagtgg tctggccgcc gattcaatcg tgtatcaact cgtttggaga 841141 gtggatgctc gggctcggcg gcatcggggc aggcatattc ggcctattca acaggctgtt 841201 aattccgctt ggccttcacc atgtgctgaa caatattttc tggttccaat tcggagaata 841261 taacggagtg acaggggatt tggcgcgctt tttcgcgaaa gatccgactg cgggcacata 841321 tatgaccgga tttttcccaa tcatgatgtt cggtcttccg gcggcgtgtc tggctatggt 841381 tgtgactgcg aagccgtcta aacggaaagc gacggctgga atgatgattg gatttgcttt 841441 aacggcgttt atcacaggga ttacggagcc gattgagttt gcatttatgt ttttatctcc 841501 gcttttatac gctgttcacg cggtcttaac cgggttatct ttatttatcg tcaactggct 841561 cggcatccgc tcaggcttct ctttttcagc cggagctatc gattatgtgc tcagctatgg 841621 aatcgcggaa aaaccgctgc ttctgctttt ggtaggtata tgctatgcgg cagtatactt 841681 tatcgtgttt tatgtactga ttaaggcttt gaatttaaaa acgcctggac gggaagacga 841741 tgatgtggat gaagtgctgg atgaaaatac tgttcaggat gtaaatgaaa acatcatgct 841801 gaaagggctc ggcggaaaag aaaaccttca aaccattgat cattgcgcca caaggctgcg 841861 actgactgtg aaggataccg ctttggtgga tgaagcactg ctaaagaaag caggcgcaaa 841921 aggggttgtc aaatcgggcg ggcaatcggt tcaagtcatt attggcccga atgtggaatt 841981 tgcagctgag gaattgaggg ctgctgtcaa ataaaaaagc ggagagggca acctctccgc 842041 tttttcttat ttatcttcgt tatcctttga cgtttcggaa gaatcttcgt catgttttgt 842101 gtaatcataa tcagaaggat tcaccttctt aaaacctttc ggctcgtaga accgcagcag 842161 gtctccgttt atgattttat cggacatttc aagttccttc ttgacgagtg agtcttctga 842221 cttgtcgact tcggattcat cgagttcttt tccggttttc gtgtcgtaat acttaccgga 842281 tattttcgtg tacttcggtg aaataaagtc tccgtttcgg aacggaatca cttcacggtg 842341 ttctttcgat aaaatatcag aaccggacat cagatagtcc ttcgtatcca ctccgagcag 842401 atgcagaatg gtaggagcca catcaacgtc tccggcatat ttatgaactt tctcgccctt 842461 cacgccggca gcgtggataa agagcggcac ccgttgaagc tgggcgttgt cgtaatcagt 842521 gatttcatcc ttgccaagca ctttcgccat cgctttattg tggttttcag agatgccgta 842581 gtggtctccg tacatcacaa taatcgattt atcatataac ccgtcttttt tcagatcatt 842641 gaagaattgt tcaatggact gatcaaggta atgggctgac tggaaatagt tatcgacgac 842701 agagtcacca aagtctccag ccgggaagtc tgtatccccc tcatccattc cgaatgggaa 842761 gtggttggaa agggtaatga acttcgtata gaacggctgc ggcaggcttt ccagcagcgg 842821 cattgattct ttgaagaacg gtttgtcttt catgccgtag tttttcgtgt tttcttcgtt 842881 catgtcatag taagcagaat caaagaattt atcaatgcct tccgccttgt acatttcgtt 842941 acggttccag aacgtctgcg tgttcccgtg gaaagtagca gatgtgtaat tcttagactt 843001 cagaatcgcc ggaacggatt gcagcgtgtt ttgcgctttg tttacgaaaa ctgaaccttg 843061 agccagcggg tacagagagt tttccatcat aaattcagca tcagatgttt taccttgtcc 843121 cgtttggtgg aaaaagttat caaagtagaa cgtttcgtta tcatgtgcca gtttatttaa 843181 gaatggtgtc acttctttgc cgtcaatttt atagtcgatg ataaatgact gcaaagattc 843241 aagtgaaacg taaatgacgt tttttccttc cgctttgccg aaatacacgt tattcggcac 843301 atcgtaattg gctttcatgt agttttctac ttccgttacg tcgctggaat cggcaagcgc 843361 gcgctggctg ttggacttga tattctgtac agcgtcataa atcgtgaaat tgtatgttcc 843421 caagtatttc acaagatagt tccggtcgaa tgatcttgtc agcaattcag gacggtctga 843481 ttccgcaact gccaggttga tcaagaacac aagaattgaa gacgcaaaaa taattcggaa 843541 cgattttttg cttgacgttt cggcaggctt gtttactttg atcgccaaga tgatcaggat 843601 gatcgtatcg ataaagtaaa aggcgtcagt cggtctcatc agcgaaaatg cgctgtcacc 843661 gagttggccg ccgtttgttt tagcctgcat aatgaccgga attgtaataa aatcattgaa 843721 aaatctgtag tacacaatgt tggcgtacag taaaaaagac attaaaaaat gaatcactat 843781 aatggctgtc tgctgtaatt ttttcttgaa caagagtcca aagccaagaa agaacaagct 843841 tgagctaaga ggattcacaa aaagcaatat tttttgtatc gtgttgtcta ttcctaagtt 843901 gaaattcagg acataaccga catacgtttt gatccataac aggacgaccg caattaagaa 843961 gaaggccagt cctctttctt ttataaatgt tttcattgtt acactccttt tttccgatcc 844021 agttcgagcg aaacgataga aaaaacgaac gtatccaata taacacgaat cagcagatta 844081 gaaaagtgaa aatcgtatga gggagaaagt ggcgaaaaac gccgtcgaat caacgtttcg 844141 ctttgatatt accaaatgta aaacaaggta tctttctaga aataaaggaa taaaatggta 844201 cattgagaat tgtatgataa aatataaggt atagataaaa agaggtgaaa tgatggattt 844261 ttcccatatt gtgtctgaag ataaaattaa gcgcgccatc aaagacgggg actttcaaaa 844321 cctcccggga atggggaagc cgctgccgaa ggatgacgcg gcacacttgc cggaatcgct 844381 gcgcatgggc tatcgtattt tgaaaaacgc gggaatggca gaggacgagg gcgcgctcaa 844441 aaaagagctt atgaccatcg accatttaat cgaaaagtgc tatgacgaaa aagaacgcga 844501 gcaattaatc agaaaaaaat ctgaaaagca attgctgctt gataagcttg tcgacaaaaa 844561 aggcatgttt tcaaagccag catccgcttt ttataagaat aaagtatatg accggcttgg 844621 acgaaacaga ccttcttcca gctgatttgt cttgtctgca ggatggcgat tgataaaagc 844681 catccttttt atgttccaag ttctatgtca aaaggtttat gtttttccat ctatgggaaa 844741 tgattcataa acgaaaaaag ggtgatggga tggaacgact attagtatgg atagagcata 844801 tatctgattg gctgtggggt ccgccgctaa tcatcctgct gacggggacg ggcttgtatt 844861 tcactatttt gctgaaaggt tttcaatttc gctatccttt atacattttc aaacagacaa 844921 tcggcagtgt aggaaaaaag ccgaagggag aaggcacagt cacaccgctt caggcattga 844981 cctcagccct cagttcaacg atcggtgcag cgaacattgt cggtgtgccc gccgctatta 845041 tgtttggggg accaggagcg gttttttgga tgtggcttat tgccttattt gccatggcga 845101 ttaagttttc tgaaagtgtt cttgctgttc attacagaga aaaaaatgag cagggtgaat 845161 acgtcggggg accgatgtat tacataacaa aagggctgcg catgaaatgg ctcggcgtat 845221 tcttctctgt tgcgctgatt gtggagctga ttcccagcat tatggttcag ggaaattcgg 845281 tttcagtctc gcttgccgag acgttttctt tcaataaaat atacgcagga atcggaattg 845341 catttttgat tgggttagtg gtgataggag gggtaaagcg gatcggaaaa gtaacagagt 845401 ttgtcgtgcc tcttatggca ggggcatacg caggtgccgg tctcctgatt gttctcatga 845461 atctatcatc agtgccggcg tttttctctc tcgttttttc aaatgcgttt acctcttctt 845521 cagcagttgg agggttcgca ggtgctgcgt tggcggaaac cgttcgctgg ggatttgccc 845581 gcgggctgta ttctaatgaa gccgggatgg gaacagcccc gattgcacat gcggcagcaa 845641 tgactgatca tcctgtgcgg caagggtttt ggtctgtgat cggcattgtc attgacacct 845701 taatcatctg tacgactacc gcttttatcg tccttgcatc cggtgtatgg acagggaaga 845761 acgcctcaaa tgacccggca gcactgacaa cggccgcatt tcagcactat ttcggttctg 845821 gaggaggata cttcgtttcg gtttccctgg tcttctttgt cgtatcaacc attatggttg 845881 tcatttttta cggcgtaaag caagctgaat ttctgttcgg gcggctggca ggacatgtga 845941 ttaaattcgt ttatttagcg gctattatca taggtgccgc aggcggagca aaagccattt 846001 ggggcgtatt ggacttagca ttggttttta ttgttgtccc gaatgtgatt gcgctcttgt 846061 tattgagcag aaaggtaaaa gcgctgtaca ccgaattctt tacatctgaa cagtactacc 846121 tgaaagatat aagaaaaacg aaacaaaagc ctgtttatcc aacaaaagaa gctaaaaatt 846181 cctagtgttt tgcttttgcg ccgaacaatg ctttgctttt tatgatcaaa taaatgagta 846241 aaggcagcaa aagagaaatc actacattaa tgattggttt gattctgtta aagtcgatta 846301 gctgatttgt atttaaaaaa aaccaaaagc cgcatacgac tgagaacatg ccggttggtg 846361 tatacatggc tttcgggtcg atttttgagt gtaaaaacga aaggccgtat accacgatat 846421 atagggaacc tgctatcttc accataatga ccggaatcca aaaagccgcg atgatcaggt 846481 ctgagcgatc cagaaaatcc gtaatgcgga tctgcctgat gaccatataa gcaggatcaa 846541 agaaagtaga tgtcaggttg ggaccaaaga cagaaattga agaaaataac atcacggcca 846601 gcaataaagc gcccagcagt atcgcgaaaa tggtgtattt tagcgggacg ctccggtttg 846661 agaagagaag cggaaggata atcaattccc ccattgtccc aaacgcgtaa tagcctgatt 846721 gaaggtatgg gattagacct tcaaaaacag gtgtcaagtt ttgaagctca atttgtgtgg 846781 ccagcgtaaa tggaaggaac aagaccagga tgccgaatgg aaataggaat atctgcgcca 846841 ttctggtcaa tgtttctttt ccctctctgg caatacagat cgccacaaag ataataacac 846901 cgccaagaac agccattggt gttctcggga gaaataaaat gttaatcaaa ttgatgaaaa 846961 aacgtatatc atgagcattg attaacagga aatacaaaga aaacagtaaa atgataatcc 847021 ggcctgcgat tggtgaggaa tcgctcagca gctcatagat atttttatcc tgatgctttt 847081 tcatcagcct atgcatgagc cagagtgccg gaatcacgat gacaacgccg aggatgtagc 847141 tgtgccaggc attttgtttt gctgattcga tcatgagaat cggagcatgc tttaatccga 847201 ctgctaacgt atacagagct ccgaaaaata atccttggta tgcagaggtc ttgtccataa 847261 agcacatcct ttctgtcatg ttcaaaacgg aatatattta aacaggtgcc ccagccgcgg 847321 aagcagggga ttcactctca tataaatcca tagaaaagca cttcctgcaa ttagcaggct 847381 gaaggcccat tttgttagat tgttagcgga acgaaaattc ttccattcat atgcgtatat 847441 ggcaatgcac acaatcaatg tctgtacgat atagctgatc atgctgacgc acctccatta 847501 atggctgatc gttttgtata ggacaccgcc ctgctcaatc gtcacaattg ggacgacgtg 847561 aacctccata tccttatata cctcttccca ttcctttttc agcagattct tcgtggttgc 847621 cgtgcttctg atggtcctgt cttgaaagcc ggccgggtcc gcctttagct tttgcaaacg 847681 atgaacggtg ctgatcacgt ccttctttat ggttctgttt aatgcttttt gaatgatgta 847741 atactggtca ttttctctcg tctcataggt tgattggttt tccataataa ttcctttggc 847801 tctgatctcg attgtcattg acagctttcc gtttttttca gcggcatgaa aggatgcatt 847861 ggacttttga agctgaatgg atgcttgccc catttgattc ggcaggtcta ctatgaattc 847921 tggctggcgg gcttgattca gcaacatcag ggctgctgtc atgtgttcat ctttgaaaat 847981 atccatcaat ctgtcctttt taaagatcgc aagcccgtca attttcaaat tagatttgcc 848041 tttccctcca ggttttgttt tagatgcaga gatgaccggt gcatacggat cactgcctat 848101 ttctactaga tcagacatga atctgcttaa gaaaacgggg cggctcgttg cgataatggc 848161 cagctcccga atcatttccg ccggaaactg ttcaagctga acatcggtat ttaaaatgtc 848221 ccgcgcttct ccccggctga ctaaaatgag cgccgttaat ctgttctgcg gatttcgcgt 848281 taaaatatca aagactgggg caacgccgtc tctcgccata tcctctccaa taatgactgt 848341 acgtctgtgg gacgtattga ttgtccgtga caaggaggtt tgcagcttgt tgttcgcttc 848401 tctgatcgta gtgccggaag ctgaatcaac ataccatgtt tttgaaccgg cagttccgcc 848461 gccgccccct gtttgtccgc ctaattggcc gaccaaggga atctgcatgg ccactcgata 848521 ctgatctttt ttcttatcaa tggctgagct gacaacaaat gcaatgtcat tgatttctgt 848581 ccggtcccag caccccgtta gaaggataca aatgagaagc ggcaaaacac acttatatat 848641 tgttttcttc atcttttggg tcctctcttt tcgctccctt ctgtccgttg ccgcgcgaat 848701 acgtgcccgg ccttctggtc atcgtccacc aaggcgccct gacaaaaata tcttttactt 848761 catctcgttt aaacggagaa atcccggata aataaggaat gccgaaagat tgcagcttgc 848821 ataaatgaag cactaagata atcgtgccga gcataatgcc gaatatccca aaaatactcg 848881 ccaaaaacat aagcgggaaa cgaagcatcc tgatggagat agctaagtta aaccgcggaa 848941 ttgtaaatga cgcgatccct gttaacgata cgatgatcac catgggggca gacacaattc 849001 ccgcttcaac agcggctgtc ccaatgacta gggccccgag aatactgacg gtctggccga 849061 tggttttcgg caggcgcact cccgcctcac ggagagcctc aaaagaaatt tccataatca 849121 atgcttctat gatggcgggg aaaggaatcg gttcacgcgc agaggccaca ctgaacatta 849181 agtttgtcgg cattaagtcc tggtggtatg taataacggc aacataaata gccggcaaat 849241 ataaagcaac gaataaaaac atatagcgaa gccagcggat taagttagac atcaaataac 849301 gctcatagta atcttcactg gcctgcataa gctgccaaaa cgtaatcggg cctgttaaga 849361 caaagggcgt attatctgtg aaaatggcaa atcggccttc gagaagctgg gcggcgacgg 849421 tgtccggcct ttctgtgtat tgcagctggg ggaatggcga gtacgtgtcg tcttcgataa 849481 attcttcaat atatccgctt tctaagacag catcaatctt tatctttttg attctttttt 849541 ttgctttgtc aataaccttt ggatcggcaa gcccgtcaat ataggccaag acaacatcgg 849601 ttttggtttt cgtgccgatt ttaaaagaga tcattttaag ctgaaacgtt ttgacgcgaa 849661 agcgcacaag agcggtattg accctgaggc tttcagtgaa gccctctctt gaccctctga 849721 tggtcgattc tgttatcggc tcttcaatgc ttcttctttg tccgcctttt atatttaaga 849781 tcaggccttt tgagtgcccg tcggcaaata aaaccgcgtt cccctcaatg atggatgcag 849841 ccactttgct catactcgtt tctaatgcaa cacttgaaat tgatagagta ttttgcagcg 849901 cctcttcatg ttcatctatt tgatccgtca aatgcattaa gaaagggcgg agggcgtgat 849961 cctgaatatg ttcagatttt acaattcctt cgatataaac aataaatccg cacagcccgt 850021 ttccaaagtc aaattgtcta aatacgatgt ctgagcagcc ttctgttaat aaggtcagat 850081 tttcgaggtt ttccttcaaa ttgggagaga tcggtctgtc ctgattgtct tcaagctctt 850141 tgatgagctg aagcgctttg tcgcgtttat tcatagaggc tcaccctgct ttttaatgtc 850201 atattcaata agtgcttgtg acttttaggg taaccttgtc tgtttcatat attccagact 850261 aggatgaaag cgctataaaa aagtgttgac tacctgtata tacaggaata caatatgatt 850321 ataagttgta tatacaagtt ataaaaacgg atacggaggg gttggcatgg gggaactgaa 850381 caaatcggca cgtcagattg tcgaagcagt cggcggtgct gaaaatattg cagcggcaac 850441 tcattgtgtt acacgtttgc gttttgcttt aatagatgaa agcaaggttg accaagagat 850501 gcttgatcaa attgatgtgg taaagggatc attctcgaca aacggacagt ttcaggtcgt 850561 aatcggccag ggaactgtca ataaagtata tgctgaactg gttaaggaaa cggggattgg 850621 cgagtcaaca aaggatgaag tgaagaaggc ctcagaaaaa aatatgaatc ctttgcagcg 850681 tgctgtgaaa acgcttgcag atatttttat tccaatattg cctgcgattg tcacggcggg 850741 tcttttaatg gggatcaata acattttaac ggcggaaggc attttcttca gcacaaaatc 850801 gattgtgcag gtttatccgc agtgggcgga tcttgctaat atgattaacc tgattgcagg 850861 cacggccttt acgtttttgc ctgcgttaat cggatggtct gccgtcaagc ggttcggcgg 850921 caatccgctt ctcggcattg tgctcggggt tatgctcgtg catcctgatt tgctgaatgc 850981 gtggggatat ggcgcggcag aacaaagcgg agagatcccg gtatggaatc tattcggcct 851041 agaggtgcag aaagtcggct atcagggcca ggtgctccca attttgcttg cttcttatat 851101 gctggcgaag attgaggtat ttttaacaaa acgcacacct gagggcatac agctgctcgt 851161 tgtcgcacca attacgcttc tcttaacagg atttgcctct tttatcatta tcggcccgat 851221 tacatttgcg atcggtaatg tactgacttc agggcttatc tcggtgtttg gttcttttgc 851281 cgcactgggc ggtctgttat atggcggttt ctactcagcg ctcgtgatta ccggtatgca 851341 tcacacgttt cttgcagtcg acctgcagct catcggttca aagctcggcg gcaccttttt 851401 atggccgatg ctggcgcttt ctaatatcgc acaaggttcg gcggctctgg ccatgatgtt 851461 tatcgtgaag gatgagaaac aaaaaggcct ctccctcaca tcagggattt ctgcttatct 851521 tggcattaca gagcctgcca tctttggggt gaatctgcga tacagattcc cgtttatcat 851581 tgcaatggtc agctctggcc tggccggaat gtatatttct tctcaaggtg tgctggcaag 851641 ctccgtcggt gtcggcggcg tgccggggat tttctcaatc atgagccagt actggggcgc 851701 gtttgcaatc gggatggcta ttgtattgat cgtgccgttt gccggaacat acgcgtatgc 851761 gagattcaaa cataaataac aagtggggag cgggacgtgt tgaacgttcc cttttcccgt 851821 tttcaattta aatatggtgg tggaaacaga tgaaaacaga acaaacgcca tggtggaaaa 851881 aagctgtggt ttatcaaatt tatccgaaaa gctttaacga tacgacagga aatggtgttg 851941 gcgatctgaa cggcattatt gaaaagctgg attacttaaa aacgctacag gtggatgtgc 852001 tttggctgac gccgatttat gattctcccc agcatgataa tgggtacgat attcgtgatt 852061 attactcgat ttatcctgaa tacggaacga tggaggattt tgagcggcta gtgtccgaag 852121 cacataaaag agacctgaaa gtcgtcatgg atcttgttgt caatcatacg tcaacagagc 852181 acaaatggtt tcgcgaggcg atctcttcaa tagacagccc gtaccgtgat ttttatatat 852241 ggaaaaaacc gcaggaaaac ggttctgttc cgacgaactg ggaatcgaaa ttcggcggct 852301 cggcatggga gcttgacgaa gcatcgggcc aatactattt gcatctgttt gatgtgacgc 852361 aggctgattt gaattgggaa aatgaagagg tcagaaagca tgtctatgac atgatgcatt 852421 tttggtttga aaagggaata gacggcttta ggcttgatgt catcaacctg atttctaaag 852481 atcagcgctt tccgaatgcg gaggaaggcg acggccgctc tttttacact gacgggccgc 852541 gggtgcacga atttctgcat gaaatgaacg aaaaggtgtt ttcacattac gacagcatga 852601 cggtcggtga gatgtcttca acaaccgtag accactgcat ccggtatacg aatcctgaca 852661 ataaagaact tgatatgaca ttcagcttcc atcatctcaa ggttgactat cctaacggcg 852721 aaaaatgggc cttggcgccg tttgattttt tgaagctgaa ggagatccta tctgactggc 852781 aaacggggat gcacgcagga gggggatgga acgctctgtt ctggtgcaat catgatcagc 852841 cgcgcgtcgt atcaagatat ggagatgatg gcgcatatag ggtgaaatcg gcgaaaatgc 852901 ttgctacggc cattcatatg atgcagggca cgccttatat ttatcagggc gaggagctgg 852961 ggatgacgaa tccgaagttc actgacataa gctcctatcg ggatgtcgaa tcgctgaaca 853021 tgtatcacgc ctttaaggaa aaaggaatgg ctgatcaaga tattacagcc attttacagg 853081 cgaaatcccg tgacaattcc agaacccccg ttcagtggga tgctacggaa aatggtggtt 853141 ttacaacggg cacaccatgg ataccggttg caggaaatta ccgggaaatc aatgctgaag 853201 cggcgctgag ggatcagaat tcggtgtttt accattatca aaaattgatt cagattcgca 853261 aaatgtatga cattgtgaca gagggtacgt atgagataat tgcaaaggat gacccgaaca 853321 tttttgcgta tctcagacac ggcagcaatg aaaagctgct cgtgatcaat aatttttacg 853381 ggacagaggc ggcctttaca ctgccggact ctttagcgcc tgacgaatgg aaggcagagg 853441 tgctgttgac gaacgatgaa gcaagggaag ggcttcagaa catgacgctt cgcccatatg 853501 agtccattgt ttatcgttta acgaaaccgt gttaaactaa gctgggtggt ccataatgaa 853561 ggtgaataaa ttcatcacaa tttataaaga catcgcacag caaattgaag gcggccgatg 853621 gaaagcggag gagattcttc cgtctgaaca tgagttgacc gcacagtacg gtacatcaag 853681 agaaacggtc cgaaaggcgc ttcatatgct cgcgcaaaac ggttatatcc agaaaatcag 853741 gggaaaaggc tccgtcgtgc tcaatcgtga aaaaatgcag tttcccgttt cgggccttgt 853801 cagcttcaag gagctcgcgc aaacgcttgg caaagaaacg aaaacaactg tacacaaatt 853861 cgggctggag cctccgtcag agctgatcca aaaacagctc cgggccaatc tggatgacga 853921 catctgggaa gtcatcaggt ctagaaagat tgacggggaa catgtgattt tggacaagga 853981 ttactttttc agaaagcatg tccctcacct gacgaaagaa atttgtgaaa actccatata 854041 tgaatatata gaaggagagc tcggtctttc gatcagttac gcccaaaaag aaattgtagc 854101 cgagccgtgt acggacgagg acagagagct gctcgattta cgcggctatg accatatggt 854161 cgtggtgaga aactacgtct ttttggagga taccagtttg tttcaatata cggaaagcag 854221 acaccgtctc gacaaattcc gatttgttga ttttgcgcgg cgggggaaat gagagaggcg 854281 cctgcctgcg gcagcgcgct tttttgtttg gtatcaaaat tgatactatc caacaaaaat 854341 gtgcgtactt ttacttttta tcataatggc tacaatagag atgagagtaa tctaaaggag 854401 aggtgtttta catggcagat ctaaagacac aaattctgga tgcatacaat ttcaggcatg 854461 cgactaagga atttgacccg aataaaaaag tgtcagacag cgattttgaa tttattttag 854521 aaacaggaag actgtctccg agctcactcg gccttgagcc ttggaaattt gtcgtcgtcc 854581 aaaatccgga attccgcgag aagcttcgtg aatacacatg gggcgcgcaa aagcagctgc 854641 cgaccgcaag ccatttcgtc ctgattcttg cgcgtacagc gaaggatatc aaatataatg 854701 cggactacat caaacgtcat ttaaaagaag taaaacaaat gcctcaagac gtgtacgaag 854761 gctatttaag caaaacagaa gaattccaga aaaacgattt gcatttgctt gaaagtgaca 854821 gaacattgtt tgactgggca tcaaaacaaa cctatatcgc gcttggcaac atgatgactg 854881 ccgctgcgca aatcggtgtt gattcctgcc cgatcgaagg cttccagtac gatcacattc 854941 accgtattct tgaagaagaa ggccttctgg aaaacggaag cttcgatatt tctgtgatgg 855001 tggcattcgg ctaccgagtg agagaccctc gtccgaaaac aagatctgct gttgaagatg 855061 ttgtgaagtg ggtttaaaag aagaaagctg ctcgcatagc gagcagctct tttttatgcc 855121 tgattcgctc tattctgttt tctcctctga tgtaagtaca ttgccgttcc gagtgcgctg 855181 atcagaaatc cggccaacag gatcgagtac atggatgtgg ctgtgtccgg aagcaggccg 855241 ccagccggac cgtctgttcc tgatccgccc gaaccgtttc caccagagcc gttagtcggt 855301 tgagtgccgg gaggcgtatc atttcctccg tttccgtcag ttggctgttt tccgcctggt 855361 ttgtcggagc ctccgccatg attgccgtca tcaccgcctg tcggttgatc tgacgggaat 855421 gccggcggtt tgttgtttga accggaattt aagatcgtgt attcgctgaa gtggtttgta 855481 tatcctgtca ccatatcatc atcgactgat ccgtgacctg tctttgtgaa agctttcttt 855541 tttctatcga cgtgataaat ggcagggtta tgggcttctt caatatcaaa catgcgaagc 855601 gaaagctgta cgggctcctt gaatgatttt atttcttttc ctttttgctt cactgtaaag 855661 tcatatacat ctgacagtga cacatccaat tctcccgtag acttgattcc gattgcagtg 855721 tctgcggttt taaggttcgc cattggcatc ttcatgctgt accagtagtt gaacatcgtc 855781 aatgaaggat ctgactctct ttctttcaaa agtttgacct gatctttttt cactttaaga 855841 ttgataggct tctcttgaga tccttcatgt attccataat agacaaatgg cgtgttggca 855901 tttttagcat aaatcgcaaa tttgtcttca tcaagtgtcc agctgccgtc cttctgcttt 855961 gtcggcagga atacttcttt gattcgtcct tcaactttag gagagacctt gtttcctagt 856021 tttttcagct gttcggtgaa aatctcataa tcaacgtagc caaggtcttc accatgggag 856081 gcttctgtaa agacagaata tccgtctcct ccggcaccga caaaattatt tgttgccacg 856141 cggtaggtat catccgtatt tatagcaact ttgtctccgt taggcgattc aattttcact 856201 tctaacacac ggtgtccagg tttgttgttt aatgtaaagg tatattcgat tccggccacc 856261 tgagggaaag cgccgccgcc attttccaca ttgcttaggc cttgttcaag ggcttcttta 856321 atttgttttc cggttaaatc ggccacgtaa agcgtattgc cgaacggcat cacgttgagc 856381 acctcgccga gtgtgatatc acctttgtca atgcctgctc tgatgccgcc gccatttgtt 856441 atcgctattc tggcgccggc tgcttctttc gcttttgcca gcataccgtc cgcgatgaag 856501 tttccgagat tcgtttcttt cgtgcgcaca tgctcacgct ggccgtcaag cgccacatcc 856561 gtgtagccga ctttttcatt tttcacgtcc tctaattcat ttttgaactg atcgagctct 856621 tgttttgctt ctgggttttc ttctgtatgt tcatcaattg gcagcacgct cagatttgat 856681 ttatctgttt gcacaacgcc tttttcatca aacgcgacat caacgcgccc caagaattgg 856741 ccgtattctt ttgcctgcgc cacgatcgtc ggttcttcgt tgttcacgac ctccattttg 856801 tctacgaggg tgtgagtgtg tccgccgatg atcaaatcaa tgccttttac ttttttggct 856861 agctcaagat cccggttatg tccgatgtgg gttaaagcaa taattttatt taccttttct 856921 tcttcttgaa tcgctttgac ggtgttttgt gctgtttcaa aggcatcatt gaatacgatg 856981 cttttgcccg ggcttgatgt ggtggctgta tcttctgttg tcaggccgaa tacggcgact 857041 ttctccccgt caacgtctaa cagaatgtaa gggtgaatgc cggcctcttt cttttcacct 857101 gccgtaaagg tttgcggctt tttgacaaat gatttcagct tgggctcatt tgacacatct 857161 acgtttgcac tgacaatcgg aaattccggc gcttcaaagt gatagcggtt cgccggatca 857221 acggttgcgc tgtttccgct tagaaaatca gaaagcaccg tcgggccttt gtcaaattca 857281 tggtttccga aggtcatggc gtcatagccc atcatgttca tcattttcag atcggccaaa 857341 ccgttccatt tagtaaaata cagatcgccg gaaaacacat ctcccgcatc aaggagaata 857401 ttgtgatttg tttcgctgcg tacttcgttg attttcgtca ttcgtctcgc tgcatcatcg 857461 agatgggcgt gcgtatcatt ggtgtgcatg acggtcagat cccacagtcc gtctttagga 857521 ggatctggat ttgaatcatc atcgaattgc agcttataca caccatagcc ttcattcgca 857581 gacttgccta cataagcgac atcgtctgct ttatcggcaa atggcttggc caaaagcgag 857641 gattcaaacg tcagattcgt gccggaaaca ggcgcgattg accagttgtt gtctgctttt 857701 ggattgactg ttttttgttc aataatgtaa tccatcagca cctgcctatt ttcaactgca 857761 gagccgtgga caattttatc gctcgtcaga tgagggaacc cgccgcctcc ggacgcacga 857821 tagttattgg tgactacgag aaattcctgg cttgggctga tcggcttgcc ttcataggaa 857881 agattgatga tacgggatga atccgcattg atcacttttc cgttctcatt gtatttagcc 857941 ggttttgtca catcgacctg atatgtgaca ccgtcaatca cgtcaaaatt ataggagcgg 858001 aaattctcgt tcagcaaggc ctggtcgccg cctttagctg gatcaatttg attgaattgg 858061 cctgctgaca tctccagcca gtccttgacc tcgctgcctg tcagcttgac gatttgaaca 858121 gtattatcgt aaagatacaa gtcaccgaca tttttaatcg caagatctcc ggctggaatg 858181 tttgtatagt aattggctcc gtttctgccg cctgctttaa acggcgctcc agcggataaa 858241 atcggcaggt tcttgtactc ggtatccttc atttcttttt cagcgtacca cttttgcgcg 858301 tcagtcacga tctgaatgga aggatcatct ttgacctgtg caaagaagct gttaatatct 858361 gcttcggttt tgccgactgg ctttcggaca tactccagtg tgttttggtg tgtttgctga 858421 atggtgtttg taacggtttc gtttcttgat gtgacgttgc cagcaataga ttcaatactt 858481 cctttggaat ctgctacctt ccatgagccg tccgcctttt caagcttgag gtcaatcacg 858541 cctaaatatt tgccccagct gcttggcatg acgacaggaa tgccgttaat tgttcccttt 858601 tccacattga actgagcaac acccgcatac tcggcggaag gaaagagtcc gtgctgatgg 858661 cccgagataa tcgcgtcaat gcctttcgtt ttggtggcaa ggtcaaacac ggcgttttct 858721 gcgcctgatg attgcgcctg cttttcaatg ccggtgtggg cgagggcaat aatgacatct 858781 gcgccttccg ccttcatttt cgggatcgtt tcattggcgg attctacgat atcctgcacc 858841 tgaacttgcc cctcgagatt ctttttgtcc catgtcatga tttgcggcgg gacaaagcct 858901 atgtagccga cttttacttt ctgctcatta ccgttttcat caatgagggt tttttcatta 858961 atcacatacg gcgtataacg gttttcgccg ctagttgttt tgacgttggc atttacaatc 859021 gggaaatcgg ctcctttgat tgtgccgtcg agaaagtcga gcccgtagtt gaattcatga 859081 ttgccaagcg ttccggcgtc gtatttcagc gcattcatga cgctgataat cggatgggtt 859141 ttcgtgccgg agataatgtc gtctttttga tatttcaccg cgtattcacc cagcggattc 859201 ccttgaatca agtcgccgtt atccacaagc agggtgttag ggttttgctc gcggtgcttt 859261 tggatcaatt gcgctgttct cgccagaccg aaatccgccg tttctttgtc gctgtagtaa 859321 tcgtaatcca tcatgttggc atgaatatca gtcgtagcca aaatactcag atgcacctga 859381 ggagccgcgc tttcttctgc atgaatgggt ggtgttggga ggattaggct aagtatcata 859441 attgggggca aaagaatacg gagaatgttt tcgacgtgtg ttcgtctttt ctgtattctc 859501 accagttctc cacctttcaa cgaaatttgt gttacagctc ctattgtaag aatattttgt 859561 aactatttgt aggtgtttct ttatgattat tgtaaaaggg agaaaaatga gtattatgta 859621 gcagtatcaa acgacaaata ctgggcattt atgcttatcg tttgtcacaa tcgcggaatg 859681 tttattttag tgtggctggg gtagagtgtt ttatgtagac atataaagcg ggaggttatg 859741 aatcatgggg aaaaaaattg cagttgtttt aacatattat tttgaggaca gcgagtacac 859801 tgagcctgcg aaagccttta aagaagcggg acatgaactg actgtcatcg aaaaagaaaa 859861 aggaaaaaca gtaaaaggca agcagggaac agcggaagtg acggttgacg cgtccattga 859921 cgacgtaaat tcttcagact ttgatgcgct tttgattcct ggaggatttt caccagacca 859981 gcttcgcgct gacgatcgtt tcgtccaatt tacaaaagcg tttatgactg acaaaaagcc 860041 ggtatttgcc atttgccacg gcccgcagct tttaatcaat gcgaaagcgc tcgacggccg 860101 aaaagcgacg ggctatacgt ccattcgtgt tgacatggaa aacgccggtg ccgacgttgt 860161 ggacaaggaa gtggttgttt gccaggatca attggtcact agccgcacac cggacgatat 860221 accggcattt aaccgcgagt cattggcatt gcttgagaaa taagaaaaaa cggacgctct 860281 tgggcgtccg tttttttgtt gcttaggctt gagcacctgt cagtttcttg tacctgtaat 860341 acaagaaagc agctgcagcc gttccgatga ccgcaatgcc gaagtcgaat atgaaaatat 860401 gggcgatgcc ccccgctttt gcgataagcc ctgttgcaat cggcagcaga atcgatgcaa 860461 gacttgaagc agtcgctaca attccggtaa cggttccttt tcgcttccag aaaagctctg 860521 tcattaacgt aatggtaatt tgaaacacac ccgcagttga aaagcctaag aaaaaggcag 860581 tgatgtccag cacaactggg atatgaacgg tcagcatgac tgcgagcgta cataaagtaa 860641 taataggata taagagcgtt atgaagacag gtttgaccca tctattcagc aaaacggcta 860701 ataataaaac agatgccaga gatcctatac tataatagct cagcaattgt acagatgctg 860761 attcagctaa accggctgcc ttttgcgcgt agctcgggag ccagatttga gaaaccgtaa 860821 ataaagccgt ggatgtaaaa ccgatgataa tcagtgcggt gccttccttc tgaaaaacgg 860881 gttcagacaa gaaaacggga gattcctgtt ggccgctatt agttggtttc ttatgttttt 860941 taggaaacga aagcgttgat aaataaataa tattcaggag atagaccgct gccggcagat 861001 aaaaagcaaa tccgtaaaac atgctgtggt ctgctaaaaa tgtgatcaaa agcggcaaaa 861061 gtgcggcccc cacagacata aaggctttaa ccaagacatt tgccgaaccg gaagcagacg 861121 gaaagagctc ggttagggcc ggatatgttc cggcatccat ggctgaatta gcgactccgg 861181 ctaataaagc gaacacaaac gccagctcat agctcggtga taaaggaata ccgactaaaa 861241 agacggccat aattcccgca gaagcgacaa caagcggctt tctgccgatt ttatctgata 861301 gaacgccgga aatgccgtat gtcagcagtt tgccaaaccc gatagcggca atgacataac 861361 tgatgccggt cggatcggta ttccactgtt ttgttaatga agacatattg gatgcgagaa 861421 tgatgttgac catccccaga aagaagtagt tgatatacat tccggatgct gttttgatag 861481 atgtcgtttg catgcttgta ctccttcaaa tcttattcga acactttgct gttttggttt 861541 ggggaaatga taaaaaagac tcgccgagtt tccggccagt ctccattatt tacgaagcga 861601 ggctaattct tgagcaatcg cctgcatttc acttgggctg aatgattctt ttttcatcac 861661 cattctgtga aggtacgtga ggtcttcaat cttctcatca ctgaaatcct ccgctttgat 861721 tacgccgacg ttcagcatgt tcagcttttg ggaaatctct tcaatcattt gagttaatgt 861781 ttctgtattt gggctggaca aagggttcca tcctttctat gcgcaatata ggtatgtttt 861841 attctaacag aattccatca gaaaaaaacc ctattctaaa agcaggctgt tcattccaaa 861901 aaagtgaaga catcagttga aaagaaaatg aacatcctac taagatattc atgaaggttt 861961 ctttttagag aaataggggc aaagaatagg gaggttgcac atcatgataa gcgtgttatt 862021 tgtttgttta ggtaacattt gccggtctcc gatggcggaa gcgattttta gggacctggc 862081 agccaaaaaa ggattagagg ggaaaatcaa ggcggactca gccggtattg gcggctggca 862141 catcggcaac cccccgcatg agggaacgca ggagatattg cgcagagaag gaatcagctt 862201 tgatggcatg ctggcgcgtc aagtcagcga acaggatctg gacgattttg attacatcat 862261 tgcaatggat gcagaaaata tcggaagtct cagaagcatg gcgggtttta aaaacacctc 862321 gcatatcaaa aggctcttgg actatgttga agattcagat ctggctgacg tacccgatcc 862381 ttactacaca gggaactttg aagaggtctg ccaattaatc aaaacgggct gtgagcagtt 862441 gcttgcatcc attcaaaaag aaaaacaatt gtgagtgaaa ggagaatttg catgaacaac 862501 gaacgtttaa tgctgaaagg gatatttctc ggagctgcgg caggcgcggc gttatcactg 862561 ctccataagc cgacaagaca ggcgtgcggg atgagatggc tgacatgcaa gcataaactt 862621 tcactgtaca aaagcaaccc agagctgtta aaaaacactg tcatcacaaa agtggatgag 862681 gccaaaaagc tcgcccgaac gctttcaaag gaagtcgact ttgtgaacca gcaggtgaaa 862741 gagctgaaga aaacaacgcc gcaagtgatg gaactcgtgc aagaaacgaa agagcatttt 862801 tcaaaaaaat gatcaaacat gcgaggtgag acgacatgag ttttttgaaa gagcttttca 862861 gcagatacac ccttcatgaa ggacaaagta aatcagcgga gctggcgtat ttttttctat 862921 tgtcactgtt tccgtttttg atttttatgc tgacgctcac cgcgtatctt ccgctttcta 862981 ccgatgatgt tttaggagtc atagaacaat atgctcccgc cagtgcgatg tcactcgttg 863041 aatccattac ccatcaaacc ttaaataatc gaaatggcgg tttgctgtca ttcgggatta 863101 tcgccgcatt atggtctgcg tctaatggaa tgaatgcgat cgtccggtcg ctgaaccacg 863161 cgtatgatgt ggaagaaaac cgctctttta tcattgttcg tctaacctcg atttttttga 863221 cgattgccat ggtatttacg attttagtgg ctttgcttct gccggtattt ggccgggaga 863281 ttggaaggct cgcttctgac tttgtcggcg cgtcggatct gtttttatcc gtctgggccg 863341 ccattcgctg gggtgtcagc ccgcttgtgc ttttgattgt tttttccgcg ctgtatgtga 863401 ttgcgccgaa caaaaagctg tctctccggt ttgtcatgcc gggtgcggtc tttgcgacta 863461 tcggctggat cattgtcagc acattgtttt cattttacgt cagcacgttt gcgaactata 863521 gcgccactta cgggagcatc gggggaatca tcgttctgat gatttggttt tacttgagcg 863581 gcattttaat tatcctaggc ggagaaatca acgctctttt acataaacgt aaaaagcttc 863641 ctgatgaaaa tccctaccat tagcgcaccc tataaacgaa cttcggttca aaaagaagtc 863701 ggggggatat cgtgatgacc aagcatacga aaaaaggcgg aagccataac aaacaaaact 863761 cgaaaagcaa atcgagccat aaaacaagcg gaagcgccaa cggacaaaac ggctaccatt 863821 agcataaaag cctcctgaca tgatgtcggg aggctttttg attaagaaga tgaagaatag 863881 gtttcagccg gtgaccagct tttcggtttg cccagcacaa gggccagcca cacagagcta 863941 agcgtgagag taatgaagta gaacaagttt gcgctttcaa atgtctgcat ataccagccg 864001 ccggcaactg ggccgaggat gctaccgaga ctgaatgtaa tgccgcaaag caggtttccc 864061 gccggcagga ggtgaggcgg aagaaggtct gtcatatagc tgatgccaag tgtaaaggtt 864121 gatccgactg ccattcctgc aataaaaaag cagccgccga tcacgtaggg cgaaggaaat 864181 acaccggcga tgaaaaagca aagagcccca gtcagtaaaa tcaccagcag cacattccgc 864241 ctgccgtatt tatcgctgag gatgccgagc ggaaactgaa agataatgct tccaatcgca 864301 aatgcgggaa ggatgatcgc tactgcgtct actgatatcc ccaaacggag cgcgtacacc 864361 ggaaagcttc cgttcagcgc cgtttccaga aagccatagc caaatgtagg cataaaggca 864421 acccacccaa acagcatggc ctgataaaat cgcctgaaac tattgtctga tttggtttca 864481 tgaggactgg tttccgggta tgcattttgt agaaagaaaa caaaaagcca cgcaaacaga 864541 ctgatgcagc cggacacgat aaaaggaagc gacggactca gcttgacaag cggcaccatg 864601 aacgggcctg cggcaaagcc aaggccaaag gaaagcccat aaatagacag gtttcttccg 864661 cgattttgtt ttgatgacat ggaggtcacc cacgtttgcg tagaaaagtg aagcatgtgg 864721 tcgccgattc caatgaacag gcgaagcagg aaccagaccc aaactgactg aagccaaata 864781 aatccgaata agcttaaaat gacaatgctt ccgcccatga cgatcagcgg cttgaacccg 864841 agctttctga gcggtgcttc cataaacggc gaagccaaaa gcacaccgat atacagcccg 864901 gtcgcgtgca ggccgttgat agcagcggat tctccatttg tttcaaaaat gattgaaatg 864961 acaggcagca gcatgccttg tgaaaacccg gaaatggaaa cgagcaagac aaggataaag 865021 aaatgaaatc gtgacatcgt gtcagttctc cttatatgga atctatgttg atcgtacaac 865081 gttttccaaa agcaggcaac ctgaaaaaag cctatatcac gctatacatt tgccctcgtg 865141 taatcatgaa ggtttttgtg aagaataaaa ataaaacaag tcataaaaaa ggagctattt 865201 caccatgaat cgtatctttt ttattttagt ggcggccggt gttccgcttt ctgtgattgg 865261 cagtttgatg cattggcctt ccgcggttct atttgcagtt tattgcgtga cgattatcgc 865321 gcttgcaagc tatatgggga gggcgacaga atcactgtcc atcattgcag gaccgcgtat 865381 cggcggtttg ttgaatgcaa ccttcgggaa tgcggtggag ctgattattt ccctttttgc 865441 attaaaagaa ggcctgacag gaatcgtgct tgcctcttta accggttcag tgctggggaa 865501 cctgttgctg gtagcgggcc tatcgttttt tgtcggcggt ttaaaatata agcggcagga 865561 atttaatatc catgatgccc gccataactc cgggcttctg atttttgcca tcattgtcgc 865621 ctttgtgatt ccggaggtat tctctgttgg tatgggaaac gccagcaagc tcaatttaag 865681 catcggcatc agcatcatta tgattctgtt atatgtggcg gcgctgtact ttaaacttgt 865741 cacgcatcgg ggcgtttatc agccgaataa tgccgctcag actgaagaag aggaagagcc 865801 agaatggtca gggaaggttg cgacgattgt cttgtttgcg gcaacgattg tggttgcata 865861 catatccgaa aacctggtcc atacctttca ctcggtggct gaacagttcg ggtggagcga 865921 gctgtttatt ggggtcatca tcgtggcgat tgtaggaaat gcggcggagc atgcgtcagc 865981 gattattatg gccttcaaaa ataaaatgga cattgctgtt gaaattgcag taggctctac 866041 gctgcagatc gctatgtttg tcgcaccggt tctcgtcatc tgttctatct tttttccgac 866101 aagcatgccg cttgtattta cattgcctga gctcgtcgcg atggtatcag cggttctctt 866161 gatgatcgcg atttcgaatg acggggattc caactggttt gaaggggcga cactgcttgc 866221 tgcatatgtc attatggcga tcggcttttt ccttctttaa cctgaaaaaa tgatggataa 866281 caacaaagcg ggatgaaaag actaagggaa aatgccatag aaagagtgat atgatgaaaa 866341 agctatttca ttccacactt attgtgttgt tattctttag ttttttcggc gttcagccca 866401 tccacgcgaa aaagcagttt aaggttccta attctgtcgc aagcatttca aaggaaaaca 866461 cgtatccgaa tgcttcacag gatcagccaa tgcttcagcc gagcaagctg gcaaaggaat 866521 tgctcgatca ttctgaggta aagattgaaa atccgcatct catcaaaatg ctgaatgaat 866581 ccaacatatc cggcacaccg cttgcagtag ggtaccgggc gacaatattt ctcgggaaat 866641 gggcgctcgg ctatgaatca aatgaaacag tcgcaaactg ggaatataaa aaaatcaata 866701 caaaccgtgc ggataaccgc ggcgggaaag aaacggctga aatgcattat gcccaggaac 866761 agcagtacag agtgaagggc ggcttgacag ctaaagttcc aaatgctgaa gatgtcaaaa 866821 gcatgatgat gcaaaaagca atgaagaaaa cgaacctccc gcttgcattt gagacggtca 866881 tcggggctgg cacaaaacgg gatcagattt ataaagtcgc tcctaaaaaa atcggttatc 866941 tacatgcata tgcaccggct gtgaatgaaa aaggaaaagt gacttacgga gaagtgtact 867001 tagtgctgaa aggaaataaa cgaaaactcg tcgtgaaaaa tgtcacgtca cagggaatcg 867061 gcgcgtggat tccggttcaa gatcatgtca cgtttggctt tcagctttcc tcactgccaa 867121 gataaataaa aaactgattc caactcggaa tcagtttttt tgtttattgg gttctctcga 867181 ttcggaccgc ttcctcaagc atttgcacat tgttttggta gagctggcga acgagaaccc 867241 gtcttactgc aaggctggca ctgaaataat catcatcttt caccatgcct ttaaccgtaa 867301 attcgacgcc gcgattgatt ttattcaatg cggtgatgcc gtggatttga aacggttctg 867361 tcggattgcc gaattcatcc cgcttcaatg aatcacgaag ctcttcattc agcatgtcac 867421 atgcctcttc caacacgctg tacacgcggt ccggatcttc tttaaagctg ataagaaagg 867481 attcggtaat ccgcataaaa tcaatattat agttctctat ttgtctgacc tcgccgttgc 867541 tgatggtgag cagcttcccg ctccattccc ggatttgcag cgagcggagg ccgatttcct 867601 ccactgtccc gttgaacaag ttgttgacgg tgacataatc gcctttgtgc agctggcgtt 867661 catatattaa gaatacacca gccagcacat ctttgatcag cgattgggcg ccaaaaccga 867721 tcacgatacc tgctacgccc gccccggcca atatcttgcc gaaatcatgc acaaataaag 867781 aaataacgta aaagataaaa ccaattgttg ccgtatactg ggtgacagaa cggacaaggc 867841 tttcaatcgt tttttccttt ttttcttcaa taaagtccgt ccgtttaaaa aatagctgta 867901 ccagccggtt gatgataaag acaccgatcc aaaggataac ggcaacgagg agaatatcga 867961 cgattttatt ttgaaaaatc tccgtaagtg tttctttcat ccgcatctaa ctcctggctt 868021 gacgttttgt gaagtctgta tcctgataat aactgttttt gacaagaaca ttcggtccga 868081 ggcaccggac attcgggcag tggcaactca gttctttcgc aagcttggtc tctctccact 868141 tttcataggc ggaagggagg ctgtccgtct gaatgttgcc aagcggcggg gtatcaccga 868201 aatcggtcac gataatgttt ccgtcgaaaa tgttcacatt caggcgggat cggccgtcag 868261 ggtcatttcg cactgtgacg tttttcgccg cgcgaagccg gcgaagcagc ttttggtcgt 868321 cttcgtccgg actgcaggca taaaacggca gcgttccgaa cagcatccac gtattttcat 868381 cacgaatatc cagcaagcgg tgaatggcct gtctcatctc tttcaggctg agggattcaa 868441 gagcgcttgc gaaatcgctt ggatacattg ggtggacctc gtgacgctga catttcatat 868501 cttctgtgat ttggcggtga atatgctcaa tatgcggaag tgttcgtttg ttcagcatcg 868561 tttccgcaga taccattact ccggcatcca cgagcgtgcg gctgttttcg atcatttttt 868621 caaaatagcg cgcgcgctgt tcgaaggtcg gttttctgtc catcatggca aagccgattt 868681 cagcaaaatc ttcaactgtt ccccagttat gtgaaatatg tagcacatcg agatacggaa 868741 tgatccattc gtaccgctcg atgtcgaggg tcagatttga attaatttgt gtccgcacac 868801 cccgttcatg ggcatatttc aataaaggaa caacatattc ttttactgat ttcaacgaaa 868861 gcatcggctc tccgcctgtg atgctgatgg atctgaggcg cgggatttcc tccagccgtt 868921 ttaacagaag atctattggc agagcattcg ggtctttagg ctgcaatgta tagcctacag 868981 cacaatgctc gcatctcata ttgcacagtg tcgttgttgt gaattcaacg tttgtcagct 869041 gcatgtctcc gtattggtca acatccatat aggcttccca agggtcaaac tcgggcgtaa 869101 tcggacgcag cttcgtgttt tgtgtcatga ctatctaact cctttataaa tgggcatact 869161 aacgctgcca acagttaatt ttagacctga tttgccaaga tcgcaagtag cgcggcgatt 869221 gaaaaacggc aaaaaatgag ctaccataat aaaaaatgaa tggaggaaca gaatggggaa 869281 cgccgtaaac aataaagatc agcagattga ttatttaaag aacagacttg acatgtttat 869341 gaacgtcatc gattcattag accctgaagc aaccgacgtt gaagatatag acaggcttat 869401 cagcatgctt gatgacctgg aagccaaata cgaacgtttt aaaaaagatt gggaataaaa 869461 ccgcgtgccc gccgcggttt ttttattggc ataaagcaac agtataaaac aaagtctcta 869521 tctgtaaaat aagaaaaaat gcagaaggag cgctggccat gaagtggatg tgttcaatat 869581 gctgcgccgc cgtattgctt gccggaggtg cagcacaggc ggaagcggtg ccgaatgagc 869641 cgattaattg gggctttaaa cgaagtgtca atcatcagcc gccagatgcc gggaagcagc 869701 tgaacagttt aattgaaaaa tatgacgcgt tttatttagg gaatacaaag gaaaaaacga 869761 tttacttaac gtttgataac ggatatgaaa atggctatac gccaaaagtg cttgatgtct 869821 taaaaaaaca tcgcgtaaca ggaacgtttt ttgtcaccgg gcatttcgta aaggaccagc 869881 ctcagctgat caaacgaatg tcagatgagg gccatattat cggcaatcat tcctttcacc 869941 atccggattt aacgacaaaa acagctgatc agattcagga tgaacttgat tcagtcaacg 870001 aagaggttta taaaattacg ggaaagcagg acaacctgta tttgcgtccg ccgcgcggcg 870061 tgttcagtga gtacgtactg aaagaaacga aacgcctcgg ctatcaaacc gttttctggt 870121 cggtcgcttt tgttgattgg aaaatcaaca accaaaaggg aaagaaatat gcctacgatc 870181 atatgatcaa gcaggcgcac ccgggagcca tttacctgct tcacaccgta tcgagggaca 870241 atgcagaagc gctggatgac gcgattacag atctgaaaaa acagggctac acttttaaaa 870301 gcattgatga tctgatgttt gagaaagaaa tgaggctgcc gtctttgtaa aagagaaaga 870361 cctctcctta aacggagagg cttttcttta ttttatacat ttaatcagtg cggcccagtc 870421 cagatccccg aagcctttct caatcccgct ttcaaaatgg ctcttggcca gctcggcaag 870481 aggaagattt gcagaaaccc gttttgcggc ggcgagtgcc aggttggtat ccttcagccc 870541 taaagacatt ttgaagccgg ccggctcaaa tttctgctcg gccataatgg ttccgtaatt 870601 ttgatagact ggagaaccaa agagcgcgct ggcgatttct aaaaattgtt tttgttctaa 870661 gccgtatttc tccatcatta aaaaggattc agataacgcc tccagcatgg acacaagcaa 870721 gaaattaatg ctgattttgg ctgcatttgc cgtcttgctt tcttcgccga cgtcaaatat 870781 ctgctggctc aggctgtcga gcagaggctt ggcagcttgc tttgcttccg ccggtccggc 870841 tgttatgata cggagcgcgg ctttggctgc ggcatccggt ctgccaagga caggagcggc 870901 gagaaaaaat tgtcctttct ctgcatgagc cgctgcgagc ttttctgaga actcaacact 870961 gattgtgctc atcgagatgt gtatgccgtt ctctgctaat ccttcaagca gcccgtcttc 871021 tccgaatgtc acggtgctga cagaatcatc atctgcaagc attgtgatga caatatcagc 871081 ggactttgcc gccagccgcg gcgtatcagc tgcctgtgcg ccttctgtga caaggtcttc 871141 tgtcttttgt ttcgtccggt tatagacagt caattcgtag cctgcttgaa gaacatttcg 871201 ggcaatgggc tgtcccatat tgccgagtcc gatgacagca attttcaatc taatcactcc 871261 ctgaatattt tttccattat aaacaatatg aacagaatat gcatagcgat cggcttacaa 871321 caaaaaagaa cagctgctcg ctgtcctcat ttaaaaatat tgaaccatcc tttatgtaca 871381 aaccaaatca gcattccaat cacaagcgcg gccatcaggc caagtacagc gaaatatccg 871441 tatttccaat gcagctccgg cataaagtcg aagttcatac cgtatacacc ggcaataaag 871501 gtgagcggga tgaaaatggt tgatacgatc gtcagtgtca tcataatcgc attcatccgg 871561 tttgagttta gcgtcacgta gctgtcacgc aagtcggacg tcatgtcacg gttggattcc 871621 acaatttcag acaactttaa caaatgatca tatatgtcgc tgaaataggc tttcgtttcc 871681 cgctgctctt tcacatggtc aaggcttaaa atccggtaga gcaaatcacg catcgggata 871741 atcgtccgtc tcaaatgcaa taggtctgtt ctgagatcaa acacctcgtt catcagcgtt 871801 ccatacgttt tgtggggacg gctttcttca atttcattca gccggtcttc aattttatac 871861 acgagaggaa aatattcatc aacaagctga tccatgatca tataagaaat atgcccgggc 871921 ccttttttca atatgtccgg tgaagcatac aaacgctccc ggactttagc gataccgggc 871981 gtttcgtgta aatgaaaggt gacgacaaat ttttcgcctt gaaagatatc gacttcctcc 872041 gtctcaagtg tttccttatt cagcgcatga atcacgtaaa aacgatagcc gtcataatgg 872101 tcaagctttg gccgctgcat atgctggaag caatcctcaa tggcaagcgg gtgaaaatga 872161 aaaaaatctc tcaataacgc cgtttccgta tcctccgggc cgtaaaaatc aacccagtac 872221 catgcaatat caggctgttc cactcgttcg atcggtatat ttttcagcag ctgatgctct 872281 gttgtgattg cggtaatgtt gatcataaac aaccctccac ctgccattat atcatgcggt 872341 ctttatgaga aaagtatacg gtactctctg cctaattcca gcggcatgtt atactgaaca 872401 aaaacggaaa aaagggtgga tctcatgtgg aaggaaaaag tatctgtcac gcctccgtat 872461 cattttgacc gcgtgctgga caggctgtct ttagaccccc tcaatgctgt tgatcgagag 872521 gcgagggaag tccgtgtgcc aatcagaaat caagcggggg acgtatgtat tgtaaaggta 872581 caggcgttag gccatgcggg cgagcctgag ttcctcgtca gcggggaaac ggatcaggga 872641 gaaatgatga aggaaatcaa gcggattttt caatgggaaa atcatttgca gcacgttctg 872701 gatcattttt caaaaacgag cctgtccgcc atttttgaag agcatgccgg gacgccgctt 872761 gttctggact acagcgtgta caactgcatg atgaaatgca ttatccacca gcagcttaat 872821 ctttccttcg cttacacgct aacagaacgg tttgttcatg cgtttggcga gcagaaggat 872881 ggcgtgtggt gctatccaaa gccggaaacg attgcggaac tcgattatca ggatctgcgt 872941 gatctgcaat tcagcatgag aaaagcggaa tacaccattg atacatcaag gatgatcgca 873001 gaaggcacac tcagcttgtc agagctgccg catatggcgg atgaagacat tatgaagaaa 873061 ctgatcaaaa tcaggggtat cggcccgtgg accgtgcaaa acgtcctcat gttcggactt 873121 ggccgtccca atttattccc gcttgccgat atcggcctcc agaatgccat caaacgccac 873181 tttcagctgg acgataagcc ggcaaaggat gtcatgctgg cgatgagcaa ggagtgggag 873241 ccttatttaa gctatgcgtc tttgtatttg tggaggagta tagaataatt cgtctgacaa 873301 tgaaggaaat cctgcaaacg tgttatacta gaaagatgtg aaaaaaccat ttcactttct 873361 gccatccgca gaaagcttca tatagaaacg gagagaacaa cgtgaaccaa caaaagaaac 873421 aggcgcccgt cgaactgaag gtcggacaaa cttttccgct gacgattaag cgtctcggca 873481 ttaacggaga aggtgttggc tattttaaga aaaaagtcgt cttcgtgccc ggcgcgcttc 873541 ctggcgaaga agttgttgtg caggccacaa aggtccagcc gaagttttcg gagggccgca 873601 ttaagaaaat ccgcaaggca tctgagcacc gggtggcacc gccttgccct gtttatgaac 873661 aatgcggcgg ctgtcagctt cagcaccttg catacagcca gcagcttcgg gaaaaacgtg 873721 atatcgtcat tcagtctctt gaacgccata cgaagtttaa agttgaaaac atggaaatca 873781 aagaaacgat tggcatggac aacccgtgga attaccgcaa taaaagccaa ttccagatcg 873841 ggcgctcgca aagcggcagc atcatcgccg gcttatacgg ccttgattct catgatatcg 873901 tgccgattaa agactgtatc gttcagcatc cggcaacgaa caaaacaaca ggcatcgtcc 873961 gccgcatttt agaggacttc aatgtgtctg tttataatga aagaaaacga aaaggcgacg 874021 ttcgcacgat cgtgacgaga gtcggctttg aaacaggcga agtgcaggtc gtgcttgtaa 874081 ccgcaaaaga aacgcttccg cacaaggaag aaatcgtcaa agcgattcaa aagcgattgc 874141 cagaggtcaa atccattatt cagaatgtaa acggggcgaa aacctcagtg atttttggtg 874201 agaaaacaaa acagctcgcc ggaaaaacag tgattcaaga agtgctcggc gacgtatctt 874261 ttgaattgag cgcccgcgct ttcttccagc tcaatccgga acagaccgtc aagctgtatg 874321 atgaagtgaa aaaagcggcg cagctgaccg gaaaagaaaa agtcgttgat gcgtattgcg 874381 gcgtcggcac tatcggcatg tgggttgcgg acggagcgaa ggaagtccgc ggcatggacg 874441 tcatcaagga atcaattgac gatgctaaga aaaacgccaa aaaacacggc atggcaaatg 874501 ccacatacgt aacaggaaca gccgagcact ggctcccgaa atggacgaaa gaaggcttcc 874561 gcccggacgt cgtcattgta gacccgccaa gaacgggctg tgacagcacg ttcttggaca 874621 cgatcaaaaa agtcaaaccg aaacgctttg tctacgtttc ctgcaatcca tccacgcttg 874681 cgaaagattt gcagacgctg tcgaaggact atcgcgtgga ctatattcag cctgtcgata 874741 tgtttccgca gacggcgcat gttgaagcag tggcgaggct tgtattaaaa tcgtctaact 874801 aaaaagaaca tttcccagtc ataaaatagt tttcctaata agacctggat ttcggtaaaa 874861 taaacaattc cgatttccgg gtctttttcg tgcgcagctc ttgtcctaac ggtctgttct 874921 caattttatc ttccttcttt tcgcggagat ctttatttta actggcgaaa agaattgaaa 874981 aaacgtgttg aaaagcaggt gaaaaaaagc gttatttaac cggaaaaata tcctcccagt 875041 atgtttaaaa tacatgagta gaatgatgta aaatcataga tgtattttca taatttgtaa 875101 aattatatat tgacttgcag ttattacgtg tgaaatattg atgataggaa tataaggaaa 875161 gtatggcgta tatcatttca agagtcattc gatgtaaaaa gttgaaacat tgtaataaat 875221 gaaagaggtg aaaatgatgg ccaaccccat tttaaaatgc ataacgtatg agcactacaa 875281 caattaaata atagtgccga gacgataaca actattacag taatacctac aatggttata 875341 tccttgcgac aatcatgctt cataatataa tgattttaga ttgacacttg gctaaaaagt 875401 attgcagaga aggaaatgga taattaaatg gataaagtat ataaaagaag ttggtttcaa 875461 acatttttgg catttttagt atctcagctt tattttaatt ttgtagaatt aacgggatgg 875521 ggtcctaagt atagagaaat gaatggattc ccagcaaaca tagttgaact agatttcttt 875581 caaacatatc tttcattcta tgataatcca tggtttaata ttattactgt tttcttggga 875641 gttttcacta ttatacaaat aattacaggg ataacaaagg atattcgaaa ttaaagcaat 875701 aacttctgat gccttattta atgatgaaag aaaatgtaca ctttcttaat tatcttatga 875761 gtgaagactg cgacacttag tcagcagtct attttatggt tctggatcag gattaccgaa 875821 ttataaccct atacaaatat atagtaggtt gccacttgct gcgttggtta ttttctaaat 875881 catgagcaaa tcccaaatga ttcagattga agttcttgaa ttcttttaaa taagggttta 875941 ttttctcttc tcatcctctt tactccatgt gattcacaag tggtagcagc ttaagtaggt 876001 tttttcattc tcttgagtac tcagttatac cacccccaac tcaatttgct ttatctctat 876061 tagtttttcc gcaaatatga tatagagata cggatatggt gtagtgttaa atatcttatc 876121 ttcaataaca gggcaattat tttgcgttgg taatatggag aactcatatg atattctatt 876181 taggttggaa tcctttttat ccaaaaagtt caaaagcaag gccactaaga aagacgaagg 876241 tcagcgccag ttaaccagaa tataaaaaat agggtagata atcatcccac gtgaaatctt 876301 caaaatttac tatagattga taagaaatgc tttcgcatgc gataagtgta aaagaagcat 876361 ggtcagtttt taatttggga taaaggttca gccgtatccc ataatgaaag gatttgattt 876421 ttgttatgac agaaaatttc tggcgtgaat taccacggcc gttttttgta ctggcaccaa 876481 tggaagatgt gacagatgtt gttttccggc atgtagtaag tgaagcaggc agaccggatg 876541 tgttttttac agagttcaca aactcagaga gctattgcca cccggatggg aaggatagcg 876601 tgcgcggccg tttgactttt acagaggatg aacagccaat tgtggcccat atatggggag 876661 ataagcctga aaacttccgt aaaatgagta ttggcatggc agagttagga tttaaaggac 876721 tagatatcaa tatgggctgc cctgtgccta atgtggcggg gaatggaaag ggaagcggcc 876781 ttatttgccg tcctgcagtt gcggcagaat taatacaagc tgcaaaagca gggggattgc 876841 ctgtaagcgt gaagacaaga cttggataca cggatgtgga tgaatggcgc gagtggctga 876901 cacacatttt gaaacaggat attgcgaatc tttctattca tctgcgtaca agggcagaaa 876961 tgagcaaagt agatgcgcat tgggagctca tcccagagat taagaaactt cgtgacgagg 877021 tggcaccaga tacattgcta acaataaacg gggatattcc tgaccgtcaa actggcttga 877081 aacttgctga acaatacggc gtcgatggaa ttatgatagg gcgcggtatt tttacaaatc 877141 ctttcgcttt tgaaaaggag ccgaaagagc atagcagcaa ggaattgctt gatctcttaa 877201 ggctgcatct ggatctccat gatgaatatt caaaagaaga agcccgtcca tacaagcctc 877261 ttcctcgctt tttcaagatt tatctccgcg gattccgagg ggcaagtgaa ttaagaaatc 877321 aatgcatgaa cacaaagtca acagatgaag tgcgtgcatt gctcgacgac tttgagagaa 877381 agtatcttga tgggatagag taacagcagt gcttgattca aaaaaggcta acaaaataaa 877441 gggattttta cacaattctt gactaaaata aacctggatt ttcggtaaat ccgggtcttt 877501 tttgtacgca gcttttactc agcctgtctt ttctctaatt tattgtaaga aaataatggt 877561 atatttagtg gagatatcat ataaaggggg agaggaaaat gaaacggcta tgcatcatcc 877621 cctgcggcaa gaaaaaaatc tgggatgtcc agcctgatgc cgggccggta agagcagagg 877681 acgcttatct cagcccgttt catcaggcgt gcgagcggta tgcaaaaaca tttttcgatg 877741 agtgggtgat tttgtcggcg aagcacgggt tcctccgccc tgatgatctc gtttcgggaa 877801 attacgatgt cacttttggc accggtcatc cggaaatcat gacagcggac gagctgcgcc 877861 gtcaatttca cgaaaaaggc ttttctgata tcgaagagct agtcatgctt ggcggaaaaa 877921 aatatcgaag cgttctaaac gccgtcatcg gagaacacca gcatatcagc tggccgctat 877981 catcatacaa aggcataggc tatatgctcc aagcgctgaa ccgggctgtt gaagaaaagc 878041 atgaactgta gcacgtacat atgaggaaaa gagtgggaac atgaaaaaac ttgtgtttgg 878101 cttgcttgcc attgtgttat tcggatgcgg actatatatc tatcatgtat ggttcggtga 878161 tccattttcg aaaaatgctg cagaacagaa gctagtgtct tatgtgaaac aaacctatcc 878221 taagaaagaa atcaagatca cgaatggggt atataacgct aaaacgtctg aatatgtatt 878281 tgaagcaacc tcccaatctc atcgctaccc aatgtgtacg aagggatttc tgcatcctaa 878341 agtaacgtgc gatggaattg aagaagcgta taccgaatca gtagcaaaac atgtaaatga 878401 agaagcaacg aaggcaatcg aagcagatct gaaaaaagcg gttcctcgat ttataaaagc 878461 tgatgctgct ttgagtatcg aaaacggaca gttcacgtta gatacaaaat ggaacaaaaa 878521 gctggctgaa aaagcgccta tgagcatgac gattcagtta gacgccagcg ggttatcaaa 878581 aacagatgcc gcaaagatgg cggaaacggt cagaaaaacg cttaatgaaa agggatatac 878641 atactcaaac ggcacgatag actgtatgca gaaggacggg gacggcggta ttggatatgt 878701 caaatattca attgattttc tttcaaaagc agctattcag tcaaacgatg cagaggaact 878761 aggaagttaa aaagatttcc aaggaaataa atacgtcgat cattgtcaaa ggccgggtga 878821 tatccggtct tttttttgca tgctgtaaaa cgagacaaat gaatcagttt gagacaaaac 878881 gagacacacg tctcaaactg tctccaaagt gaagatgaga agactgattt tacgggctca 878941 aaagactggc acacttcttg catttataat ggtgaaccct aaatagaagg aggcgcacaa 879001 aatgaaattg ttaaaacgag aaggcttgtc attaactgag gaaaaagcgc tgtggatgta 879061 ccaaaagatg ctggagatca ggggctttga agacaaagtg catgaactgt tcgcccaggg 879121 agtgcttccc ggattcgttc atttatatgc cggtgaggaa gccgtggctg taggggtgtg 879181 cgctcattta catgatggcg acagcattac aagcacccac aggggacatg gacattgtat 879241 cgccaaaggc tgtgacctgg acggcatgat ggcggaaatt ttcgggaaag cgaccggatt 879301 gtgcaaaggc aagggcggtt ctatgcacat tgcggatctt gataaaggca tgttaggcgc 879361 aaatggaatc gtcgggggcg gctttacgct cgcatgcgga tcagcgctca cggctaaata 879421 taaacagact aaaaatgtaa gcgtttgctt tttcggggac ggggcaaata accaaggtac 879481 cttccacgaa gggctgaatt tagcggctgt atggaacctt cctgtcgtat ttgttgctga 879541 aaacaacggc tatggcgaag ctaccccatt tgagtacgca tcagcctgtg attcaatcgc 879601 cgatcgggcg gctgcttata acatgccggg ggttacagtt gacggcaaag atattttagc 879661 agtttaccag gcagccgagg aagcgataga aagagcaaga aacggcggcg gcccgtcttt 879721 gattgaatgt atgacctaca gaaactacgg ccatttcgaa ggagatgccc aaacctataa 879781 aacgaaggat gaaagagttg agcaccttga agaaaaagat gccattcaag gttttaaaaa 879841 ctacctttta aaagaaacag atgctaataa gctgtcagac attgaacagc gtgtcagcga 879901 atcgattgaa aaagccgtct cgttcagcga agacagccca tatccaaaag attcggagct 879961 gctgacagat gtgtatgtgt catatgaaaa aggaggaatg taagagatgg cgagagtcat 880021 aagcatgtca gacgcgatca atgaagcaat gaagcttgcg atgagaaaag acgaaaatgt 880081 gcttttgatc ggtgaggatg tcgccggggg agcggcggtc gatcatttgc aggatgatga 880141 agcatggggc ggtgtattag gggtcacaaa gggactcgta caggaattcg ggcgtacaag 880201 agtgctggac actccgattt ctgaggcagg ctatatggga gcggctatgg ctgcggcatc 880261 aaccggtttg agaccgattg ccgagctgat gtttaacgat tttatcggca cgtgctttga 880321 tcaggtgatc aaccaagggg cgaaattccg ttatatgttc ggcggaaaag cgcaagtgcc 880381 gattaccgtc cgcaccacat acggagcagg gttccgggcc gctgcccagc attcacaatc 880441 gctgtatggc cttttcacga gcatccctgg actgaagaca gttgttccat ccaatccgta 880501 tgatgccaaa ggtcttttgc ttgcagcaat agaagataat gatccggtgt ttttctttga 880561 agacaaaacg tcctacaaca tgaagggcga ggtgccggaa gattattata caattcccct 880621 cggaaaagcg gatatcaaac gcgaaggcaa tgatgttacg ctctttgcag tcggcaagca 880681 ggtcaatact gcgcttgaag cggctgcaca gctttcagag aggggcatcg aagccgaggt 880741 ccttgatccc cgcagtctgt ctcctctgga tgaggatgcg attttcacat cgttagaaaa 880801 aacaaaccgg ctgatcatca ttgatgaagc caatccgcga tgcagcattg ccacggatat 880861 tgctgcgctt gtcgctgaca agggctttga tttgcttgat gcgccgatta aacggattac 880921 agcgccgcat acaccggttc cgttttcacc agtgcttgaa gatcaatatt tgccgacacc 880981 agataaaatt gtcagcgtca cgcttgaatt gcttggcgag ccggcattga attaaagggg 881041 ggacacaaat ggcggtaaaa gtagtgatgc caaaattggg aatggccatg aaacaagggg 881101 aagtatcgat atggaataaa aaagtaggcg acccggttga aaagggagaa agcattgcca 881161 gcattcaatc ggagaaaatt gaaatggaga tcgaagcgcc tgaaaaagga acgctgatcg 881221 atatcaaagt gaaagaggga gaagaggttc cgcccggcac agctatctgc tatatcgggg 881281 acgccaatga gtcggtgcag gaagaggcgg gggcgcctgt tgctgaagac aatatgccgc 881341 aagccgtcca gcccgtcaaa caagaaaaca aacccgcagc ctccaaaaaa gatcgaatga 881401 aaatatctcc agtcgccagg aaaatagcag aaaaagcagg attagaccta aaacaactga 881461 aaggaactgg accaggcgga cgaatcgtga aggatgacgt aacaaaggct cttgctgaac 881521 agaaaaaaga tcaagcaaag cctgtttcgg agcagaaagc gcaggaaatc ccggtgacag 881581 gcatgagaaa ggtcatcgct gcccgaatgc aggaaagcct ggcaaacagc gcgcagctga 881641 cgatcacgat gaaagctgat atcaccaagc ttgccactct tcaaaaacag ctttcaccaa 881701 ctgcggaaga gagatacggc acaaaactga cgatcactca ttttgtctca agagccgccg 881761 ttctcgctct gcaagctcac cctgtgctga acagctttta tcaaaatgag cgcatcatca 881821 cacatcccca tgtgcacctt ggtatggctg tagccttgga aaatggctta gtggtgcctg 881881 tcatccgcca tgctgaaaag ctatcgctga ttgaactggc tcaatccatc tcagaaaatg 881941 ccaaaaaagc acgcgaggga cgtgcgggaa gcgaagaact gcaaggatct actttctcca 882001 ttacaaacct tggcgcgttt ggagttgagc atttcacacc gatactaaat ccgccggaaa 882061 caggcattct cggcatcgga gcaagctatg acacaccggt gtatcaaggg gaggagatcg 882121 tcagaagcac gatcctgcca ctcagcctga catttgatca cagagcgtgt gacggcgccc 882181 ctgccgctgc attcctgaag gcgatgaaaa catatttgga agaacccgca gcattaattt 882241 tataggaaaa gcaggtgaaa acgacatgac attagccatt atcggcggcg gacctgcagg 882301 ctatgcggct gcggtttccg cggcacagca gggcagaaac gtgctgctca ttgacaaagg 882361 caagcttggg gggacctgcc tgaatgaagg ctgcatcccg acaaagtctt tgttagaaag 882421 cgcaaacgtt cttgataaaa tcaagcatgc cgacagcttt ggaatcgaac ttccggcagg 882481 tgcgatatca gtcgattgga gtaaaatgca aagccgaaaa caacaggttg tcagtcagct 882541 tgtccaaggc gttcagtacc taatgaagaa aaatcaaata caggttgtaa agggaacagc 882601 ctcctttctt tctgaaagaa agctcttgat cgaaggagaa aacggaaaag aaatcagaga 882661 ggcggaccaa gtattgattg cctccgggtc agagccaatc gagctgcctt ttgccccatt 882721 tgacggcgaa tggatcctcg acagcaaaga cgcgctttct ctttccgaga ttccgtcttc 882781 actagtcatt gtcggcggcg gtgtcatcgg gtgtgagtat gcagggctgt tcgccagatt 882841 gggatcgcag gtgaccatca ttgaaacagc ggaccggctg atcccggctg aagatgaaga 882901 tattgcccgt ctctttcagg agaaacttga ggaagacggt gtcgaagtgc atacttcatc 882961 cagattaggg cgggtggatc aaacggccaa aacggcaata tggaaaagcg gtcagcgaga 883021 gtttaaaacg aaggccgatt atgtgctggt ggcgatcggc agaaaacccc gtcttgacgg 883081 attgcagctg gaacaggccg gagttgattt ttctccaaag ggcattccgg tgaatgggca 883141 catgcagacg aacgtgcctc atatttacgc gtgcggagat gctatagggg gcattcagct 883201 cgcgcatgcc gctttccatg agggcatcat cgctgcttct catgcttccg gaagggatgt 883261 caaaatcaat gagaaacatg tgccgcgctg catctatacg tccccggaaa tcgcgtgtat 883321 cggaatgaca gaacgacagg caagaagcat atacggggat gtgaagatcg gcgaattttc 883381 attttccgca aacggcaagg cgctcattaa acagcaagcg gaaggaaagg tcaaaatcat 883441 ggctgaaccg gaattcggcg aaatcgtggg tgtctcgatg attggcccgg atgtaaccga 883501 gctcatcggc caagcggcag cgatcatgaa tggtgagatg acggcagata tggcggagca 883561 ttttatcgcc gcccatccga ctttatcgga aacattgcat gaggcgctgt taagcacgat 883621 cggccttgcg gtacatgcat aataaaggaa aaagcaggcg catggatata aggcgcctgc 883681 ttttttattg ttgaaagcgc tttatttttc ccctacaata gatgaaaacg gcgtgtaagg 883741 gaggagcgat caaggaaatg aattcggtcc caaacgattt gcaaacctgg aaacgttttg 883801 tgaaagacgg tgtgcttgac gaagcccgat taagaaaacg gattgcagag tcatggcatc 883861 gctgcaaaaa agctgaggtc aatccttatt tagaaaaagg cccgaaggtt ttacagcaaa 883921 cggagctgga tcagcagtca aaaaaacatt cattcttctt gacgaccgca aagccttacc 883981 tcgaaaaact gctgcctgcc ataaaagaaa tggaaatgat ggcgctgtta attgattcag 884041 acggtgttgt tctggcattg gacggccatc cgcgcgcgct ctatgaagcc aaacgcatca 884101 atttcgtcga aggggcatgc tggacagaaa cggctgtcgg aacaaatgcg attggcacgg 884161 cgctccacat cagcgagccg gttgcaatac aaggatcaga gcattactct atcgcttccc 884221 atctttggaa ctgttcagct gctccgattc accatgagga tggcagcctt gcgggtgtaa 884281 ttgacatatc atgcccggcg gcaggcgcgc atcctcatat gcttggtatt gccacggcga 884341 ttgcctatgc cgctgaacgg gaactcgcag ctaaaagccg tgagaaagag ctggagctga 884401 tcagccgttt tggggagaga gctgcatcca gtgtgccgat ggtgctctgt aataccaagc 884461 agcacatcat cagtgcgagc atgccgattc gaacctcaat gccggattgg cagggccggc 884521 acctgtacga gttgaaggaa cggggctatt caatcgaaaa tgctgtcacc ataggagatg 884581 gcggcacttg tttttatctt tcggaacaaa agaaaaagaa ggcgtttcga ttcaatggag 884641 tgatcgggca aagcggccga tcgcaagcga tgctgatgca ccttgaacga gcagctgcga 884701 cggatgcatc ggtctgtttg tcgggtgaaa cgggtacggg gaaggaggtc gcggctcgcg 884761 cgcttcatga gaacagtgag agacggcacg gtccgtttgt tgctgtcaat tgcggagcga 884821 ttccgtctga tttgattgaa agcgaactgt tcggatatgc agagggcgct tttacgggag 884881 cgaaacgaaa tggctataaa ggcgcctttc aaaaagcgaa tcaaggcaca ttatttttag 884941 atgaaatcgg agaaatttcc cactcgatgc aggttgcact tttacgggtg cttcaggaac 885001 gcaagataac gccaatcggc gggacgaaag aaattccggt tgatatcaga gttattgccg 885061 ccacacattg tgatttacgc gagcttgccg aaaacggaaa aatcagagag gacttgtttt 885121 accgtcttca tgtctatcca attgaactcc ctccattacg cgatcgcacc gaggatatcc 885181 cggatctctt tgagtactac aaacagaaga atcattggcc aggcgatctt ccttctgatt 885241 tttgtaatgt gctgaagcaa tggaagtggc cggggaatat ccgcgagctg tttaatgtgt 885301 ttgaacgtct ttctatcaga tttccggacg gccggctgag agatgaatcg cttcccgctt 885361 tactggaagc cgctggattg ccggccagct ctgcagaaaa aaagccggct gctgccggcg 885421 tgcttacttt tcgtgagcaa atccaaaagg atatgatgat caaagcgctt gaatctgcaa 885481 aaggaaacgt ctctcaagcc gcaaaaatca gcgggatccc ccgaagcact ttctacaaac 885541 gcctgaaaaa attcaacttg tccgctgaat cataaagcat acttccttca ggaaatggaa 885601 acgttatgta ttgaaggagg gtgttacgat gaatattcaa agggcgaaag aaattgtaga 885661 atctcccgac atgaagaaag taacatataa cggcgttcct atttacattc agcacgtaaa 885721 tgaagaaact ggaacagcaa gaatttatcc gcttgacgaa ccgcaagagg agcatgaagt 885781 gcagctgaac agcttaaaag aggattaaac aaaaatggcc cgcttcataa gcaggccatt 885841 ttgttatccg cgcggcgcaa ataaaataac acagacaccg atgagacaaa tgaatgcgcc 885901 gatccagtca tacagatcag gtgttttccg gtcaacaagc catccccaca ggaccgcaag 885961 cacgatgaat actccgccat aagcggcgta tacacggccg aaagatggga aggactgaaa 886021 cgtcggaaga atgccgtata caatgaggat cagcgccccg gcgattccgt agccagctgg 886081 ctttgcctct ctcagccata gccaaaccag atatccgccg ccaatttcag caagccctgc 886141 cgcgagaaat aaaagaatgg taatcagcat catgagcact cctcaatttg catttatctt 886201 tcattataga ggaggagagc ttttaaagct tcggatgatt ctcaaattcc ttcaaatacg 886261 cttttcgctg aacctctgta aattggctga tccaattgtt ttgagcctct tcattcaaat 886321 ggggaaggat atagcgttca accgcttcga aaaacagcgg attcgtgatg atgttccagg 886381 tcgggattcg aacgattttg ccgtctgttt tctcgatgat aatatcctca aaaaagatcc 886441 ctttcaaact gtattgatgg cgtcccatat aaagccgctt cacctcggaa aacagcacgc 886501 tgcgctttct caagaagatt tcgccactag gtccggtctt tatggtgaaa atgacatttc 886561 cacggcttgt gaacgcagga aaagccataa agaatgtgat caatccataa atcatcgcca 886621 gtaatccgcc gcccaaataa agcagggcat atttagattc aaacgtgagg gcttcagaca 886681 ccagccagac tcccacaata aaggcgcccc ctgtagcgag gaacagccaa gcccttagaa 886741 acatcatgct ttttacttca atcatgtgct gcccctaaag cttcggatga ttctcaaatt 886801 ccttcaaata cgcactgcgt tggatgtctg taaactgtcc gatccaattg cttttcgcct 886861 cttcattcag atgtggaagg atatagcgtt caaccgcttc gaaaaacaac ggattcggaa 886921 tgatgttcca agtgggaatg cgaatggtct tctgatccac ggtttggatc aatatatctt 886981 cttggaagat tccttttaga ctaaatttat ggcggctcat ctcaattttc ttgatatcag 887041 taaacgtaac agacactttg tcagtgaaca cttctccatt ttttcctgtc ttgatgcgga 887101 aaatggtatt tccccgcggg gtgaaagccg gaaagaagat gataaataaa tataaacaaa 887161 acaaggtgaa cagaaagcca gcaggaatgg ctaataggta atatttcgtt tgaaacgtaa 887221 tacccatata aaagagccac aaacatgcta atcccatacc ggcagatccg acaaaagccc 887281 atattctcag gaacattttg cttttgactt caatgatttc ttggtttttc aatgcttttc 887341 tccttttgtt aattcaattc ttatcatttt gaaatgattt gatttacaac atccttatga 887401 gcagggagga tagaaaattc attctgggtg atgcctgtga caagccaagt atggtgggcc 887461 cccggcagga cgaatgccat gtcagccact tcaggagtgt tatcttttcc atatgccaga 887521 cgcataagtg tatccatttt ccctttccgc aaagccagat catttgcaaa tcgggtaacg 887581 tcctcttggt ggtcatgttt ttcaaggaac tcttttagat atgaagggtt gtctgaagcg 887641 ccctccaaga gtttttcaaa ttcatttgat gtcaatgtta caatcgattc tcttttatcc 887701 tctgtatcta ttatatgtaa aaactcatct gtcttagcaa gtaacccttc acttgattcc 887761 atttttgtaa tgcgatggac ttgttcatca aaaaggagtt cgtgagagta ggtgccgaat 887821 tttgatacat ggcatgacac attctgttcg gcaccttgcc cgttaaattt agaaagcttc 887881 actgtatagt cagcgtcgtt taatacatgg ataaacggac agtactcgtc ctttaaccga 887941 tattgatggt tccgatattc cgctgcatcc ttggctaaga gtgagcggca cgcggcttca 888001 aataaggcgc cgagctgttc atcttctatt tccggaaaat aggcctgctt caaggccatt 888061 ccctgttcaa aaaacccttc gctgtaaaag caaaacaaga gttcttctat gctaattgta 888121 aactgcttca ttgtttattc tcctatccaa atgaaaattt ccctttaagg aaatgggttg 888181 cgccgtgtat aagcgaatcc gctgttttct ttgctttttc cattcctttt ttcgcgctgt 888241 ctatcccttt atgtatcgat ttattcgccg catctatgcc gtcattcact gatttgacga 888301 ctttgccggc tgattccagc ccttttttgg ctgtatcaac aacagcatgg atcggttctt 888361 tcagctttaa ggctgctttt tcagcaaaac cggctgtata tttggcgatt tgttctccga 888421 cgactccgcc aatgtatgaa cctgctgccc caagaaggac agtacccaca ggtcctgcaa 888481 agcttccgat tgcaccgccg atgacagcac cagctgtggc accgccggca acaaaaatcg 888541 tattattcac agcattcccg acggccttgg cgttttcacg cttgagaact tccggtttat 888601 cctggtattt tgcataattt tcagcaattt tcacgcctgc tccgaatgtt tcggtcgctc 888661 cggtaatcag tgtggcggta atggcatttc ctttcgcgaa tctcaagccc gtttttccca 888721 catccttcaa agtggagcgt acgccggctt cattaagaaa tccttttgtg tagcttctga 888781 cgctgtttga aaaatccacc gtgtcctgag gaaagtattt tgtaaacttt ttatgtacca 888841 aatctgaaaa tggacggttt gtctttttca acaaatattt aggattcaaa agcactcttg 888901 ccgctttttg ataacgtgag ctgtcaacgg ccctggaaat atccaagagc agttttgagt 888961 gctgggctgt atgcaagccg cttggttgtt tcacaaattt cgtaagccct aatccgtaat 889021 attttccctg cgtcagcata agagcggtta agcttgtcat cgtaccgtat ttgtcgtagg 889081 cattgtagag ctttcgcaaa atatcatctt gttccacaaa tttatcgcct gtttttctga 889141 tgaaaatctc attgtcactc agcttagtga cgagcgcctt tcctgagctc cacgcatcgc 889201 ccactccaga aaaacagctg ctgtagcggg gatcgcattg caaaatcatc tgccccagct 889261 ccacatgcag gtccttatat ttgttttcca tatcagttaa ttcagtgact acatcatttg 889321 caagctgttc gagcttatcc ggatcaactg caatgtttcc tgacacaccg ttcacctccc 889381 gagtttatgt ctttcctctc ttgctttacg ctccagttct tccattctgg caatttcagc 889441 ttttcgttct tctattttga cagcggcagc cttcagctct tggcttgttt caagcagctc 889501 ctgttcgaat tgatcgtagg cggctttcgt ttcctcgaaa tcctggtcaa acgaatctct 889561 tgctttgccc tgccaagcat ctcccaatgc agataaccgg gattcaagca gcattttgga 889621 gcttctgacc tcttctgcgg ccgcactata cttgtttgcc agctcaatga ctttatatga 889681 gtccaacttt tgtcccctgc cttttctaaa ttcacgcaca attggatgtt ttatataaat 889741 gattataaat aattcggcat gtatccgaat cgtacaaaag aaccttttca taagaattgg 889801 aagggcgtat attcacttaa aattcacagt tggtgagact ttaagattac aaaaaaggta 889861 aaaaaaccaa atctctcaga cataaggcaa atgagaaatt tcccgctcta tgggaaaaaa 889921 cactaaagtt gatcaaatga cctaagtgcg ccaaacgtgt tacgggacga gctatctcat 889981 ggtataaatg gaattgtaaa cgttatcaag gaggtcgtca tatgaagaaa aaatcattct 890041 caatcgtaat agcgggcgga gggagcactt tcactccagg gatcgtactc atgctcttgg 890101 accatttgga ggagtttccg atcagaaagc tgaagctgta tgataatgat aaggagagac 890161 aggatcgaat tgcaggcgcc tgtgacgttt ttatcagaga aaaagcgccg gatattgaat 890221 ttgcagcgac gactgacccg gaagaagctt ttacagatgt cgattttgtt atggcgcaca 890281 tcagagtagg gaaatacgcg atgcgcgcgc ttgatgagca aattccgtta aagtacggag 890341 ttgtcggcca ggagacgtgc gggccgggcg ggatcgcata cggtatgcgt tcgatcggcg 890401 gtgtgcttga aatattagat tacatggaaa aatactcgcc tgatgcgtgg atgctcaatt 890461 attccaatcc ggcggcaatt gtggctgaag ctacgagacg ccttagaccg aattctaaaa 890521 ttctcaatat ctgtgatatg ccggttggga tcgaagaccg gatggcgcaa attcttggct 890581 tatcctcaag aaaagaaatg aaggtccgct attacggatt gaatcatttc ggctggtgga 890641 catcgattca ggatcaagag ggcaacgatt taatgccgaa gctgaaggaa catgtatccc 890701 aatacggtta tattccgaaa acagaggctg aagctgtgga ggcaagctgg aatgacacgt 890761 tcgccaaagc gcgtgacgtg caggctgcag atcctgacac actgccgaat acgtatttgc 890821 aatattattt gttcccagat gatatggtga aaaaatcaaa tccgaatcat acgcgggcga 890881 atgaagtcat ggaagggcgc gaagctttta ttttcagcca atgtgacatg atcacacgtg 890941 aacagtcctc ggaaaacagc gaaattaaaa tcgatgacca cgcatcgtat atcgttgatc 891001 ttgcccgggc gattgcctac aacacaggtg aaagaatgct gttgattgtt gaaaataacg 891061 gtgcaattgc gaactttgac ccgactgcga tggttgaggt gccatgcatc gtcggctcaa 891121 atggacctga accgattacc gttggcacca ttccgcaatt ccagaaaggg ctcatggagc 891181 agcaggtatc cgttgagaag ctgactgttg aagcgtgggc agagaaatcg ttccaaaagc 891241 tgtggcaggc gctgatcctg tcaaaaacag tgccgaacgc gcgtgtggca agactcattc 891301 ttgaggattt agtggaggcc aacaaagact tctggcctga gcttgatcaa agcccaaccc 891361 gcatatcata aatgaaattc ccccattttc gaatctgtaa ttgtatataa tagaaagaaa 891421 atggggggat ctgatatgca gctcgaagaa ctgatcaatc agcactacag caaattgaat 891481 gacaacgatt ttcatatttt aaaatatata ttgaatcata agcacacatg ctatcacctt 891541 ggaatcgacg cgctggccaa agcttgcagt gtatcgcgtt cctcaatttt acggcttgcc 891601 caaaagctcg gtttcagcgg ttacagtgaa tttcgcgtct ttttaaagtg ggaagatcag 891661 ccggaagaag gcgagagtat gagttttgaa aagctgcttg atgatattga agcaaatttg 891721 aagtttttac ggacaaagga catgacggac atgtgccagc tgattgatgc agctgaccgc 891781 attttcgtct acggttctgg aaatgcgcaa aagatatgcg cccgcgacct gcaaagaatg 891841 tttattccgc gccatcgcta tcttattttg attgaagaca caaatgaatt taatttgatg 891901 cgcgatgatt ttaaagtgaa cgatctgttt atcatcattt ctctttccgg agaaacaccg 891961 gagctgattc ctcaggcaag aatgctttct gcaaagggta ttccctttat ttccattacg 892021 aatttaaaaa acaatgtcct cgcccagctg actccgcata atctttatgc gacaagcaaa 892081 cctgtgacat taagcgatag aacggaaatt gtcgcttttg caccgttttt tctcgttggc 892141 gaagcattgt tccgcgcata tgttgattac aaagaggcag aaaaaaatga caatgagtag 892201 cagggggttc tggtatgatg caaaaaattc agcgctttgg aagcgcgatg tttgtgcctg 892261 ttttattatt cgcgttcgcc ggcattatcg tcggtatcag cacgctcttt aaaaataaaa 892321 ccctcatggg accgctcgcc gatcctgacg gtttttggta tcagtgctgg tatatcattg 892381 agcagggcgg ctggactgtt tttaaccaaa tgccgctctt attcgccatt ggcatcccgg 892441 ttgctttggc gaagaaagct caggcacgcg cctgtttgga agcgcttact gtctacctga 892501 cattcaacta ttttgtcagc gcgatattga cggtatgggg aggagcattt ggcgtcgaca 892561 tgaatcaaga ggtcggcgga acgagcgggt taacgatgat tgcgggcata aaaacgctcg 892621 ataccaacat catcggagcc atctttattt cttcgattgt cgtctttttg cataatcgct 892681 attttgataa aaaactgccc gattttctcg gcatctttca aggctcaaca tatatcgtga 892741 tgatttcctt ctttattatg atcccaattg cgttggctgt gtcttatatt tggccgatgg 892801 ttcaatcggg aatcggctcg cttcaaagct tcctggttgc ttctggggcg gtgggcgttt 892861 ggatatacac gtttttggaa cggattttaa ttccgaccgg ccttcatcac tttatttaca 892921 cgccgtttat ttatggcccg gctgtagcgg aaggcgggat cgtcacgtat tgggcacagc 892981 atctcggcga atattcgcaa agcgccaaac cgctgaagga gctctttccg caaggcggat 893041 tcgcgcttca cggcaactcg aaaatcttcg gtattccggg tatcgccctg gctttttatg 893101 tgacagccaa aaaggaaaag aaaaaactcg tcgcagggct gctgattcct gtcacactga 893161 cagcgattgt cgccggtatt acagagccga ttgagtttac gttcttattc atttcacctt 893221 tcttatttgc ggttcacgcc gtgcttgccg ccacaatgtc gacagttatg tatatggccg 893281 gcgtcgtcgg aaatatggga ggcggactga ttgaggcggt aaccttgaac tggattccgc 893341 tctttggcag ccacggtatg acatatgtgt atcaaatttt gatcgggctc tcgtttacag 893401 caatttattt tttcgtcttc agatttttaa tcctcaaatt caatatcgct acaccaggac 893461 gggaaaagga tgaacagcag gaaacaaagc tatattcgaa aaaggaatac agagaacgaa 893521 aaaacaagga tgaaacggcc tccgctgctg aaacggctga tgacaccgct tttctgtata 893581 ttgaagcgct gggcggaaaa gacaacatca ctgaagtcac aaactgcgcc acccgcctca 893641 gagtcagtgt caaggatgaa acaaaggttg aacccgacag cgtattccgc gcgcttggcg 893701 cacacggcgt tgtcaggaac gggaaggcgt ttcaggtaat tatcggatta agcgtgccgc 893761 agatgcggga gcgtgtggaa aaaatattga atcaataaag actgccctcc ttttcgggag 893821 ggttttcgtt tgccgtcaaa aagaccgcca tagtaaagta aagaaagaga caatcgagta 893881 aaaaggggtt tggaggcttt tacatgcaaa aggctttgtc gtttttaaaa ccatattcat 893941 tgctggcggg aattgctctg attcttatgc tgacggagct tgcagttgaa ctgatgcagc 894001 ctttattgat tgcaaaaatc atcgacgatg ggatattgaa gcaagatctg cggcatgtat 894061 ggatatgggg cacggtcatg atcgggctga ccgtgttatc ctttgcggcg gggatgctga 894121 attcctttta tgccgcccat gtcagccaaa gcttttccta tgatacgaga aaagggcttt 894181 ttcaaaaaat ccagtccttc tcctattcca catttggaca gttttcgtcc tcttcttata 894241 ttacaaggct gacaaacgac gtcacacagg ttcaaaatat gatttttatg agtttgcggt 894301 ttatgctgcg ggctccctta atgattgcag gcggcattgt gctgtcgctt gccgttaatg 894361 tgaaactcgg gttttttctg cttgtgacca ttccgatcct gatcttgttt ttgctatggg 894421 tattaaggaa aggcggggca ctgttccgct cagtgcagaa aaggctggat caagtgaaca 894481 ccatcatgca ggaaaattta attgcaatca agctgatcaa agcgctgctt cgcggcagcc 894541 acgaagtcaa acgatttatc aaagccaaca caaggctgat ggaaaaaacg gtttcggcct 894601 ttcagcttgt ggaattcacg atgcctgtac tgatgctgct gatgaatctc tgcatccttt 894661 tgattttgtg ggcggggtcc tacagtatta cgagcggaag cactcaggtt ggcgatgttg 894721 ttgcgataat taactacgca acacgaatta caggcgcgct ttcgatgttt ccgtttttga 894781 ttatgatttt cacccgggcg aaggcttcag gggatagaat cggtgaggtg cttgaaacag 894841 aaggcgacga gcgggaggaa ggcaccatat ctgatcgttt gtcaggacgg attgagtttc 894901 agcatgtatc ctttcgctat cctgaaatgg acagagaagc gctcaggaat gtctcatttt 894961 ccgcaaagcc aagagaaacg atcgcgattc tcggtgcgac gggctcgggc aagtccacgc 895021 tttttcagct cattccgcgg ctttatcagc cggattcagg ccgcatttac atagatgaaa 895081 agccggttca agatattccg gctgaagggc tgcgcaggca aattggatat gtaccgcagg 895141 aagtcctctt gttttccggc acaatcaaag aaaacatcgc ttggggcaaa gaaaatgctt 895201 cactagatga aataatggat gcggcaaaac ttgcgcaaat tcatgaaacg attttaaagc 895261 tcccaaatgg atatgacact gttttggggc aaagaggcgt caacctgtcc ggcggccaaa 895321 agcagcggat ttccattgcg cgggcgctga ttcgaaaacc ggctatcctt ctattagatg 895381 acagcacaag cgcgcttgat ctgcaaacgg aggcgaagct gcttgaagca atcagcacat 895441 accattgcac aactttgatc attacacaaa aaataaccac ggcgatgaaa gctgatcaga 895501 ttttgctgct tgaggacggc gaactgattg aaaaaggcac tcacagtgag ctgctttctg 895561 aatctcagtt atacaagcgc atttacgagt cacaattcgg aagggagggg agcgagtcat 895621 gctaaaagac atccgcaagc ctttccaata tcccaaactg ccaattgaca aaaaagaagg 895681 cgcgaaaaag cgggcgaaag caaaggatac aaagggcaca ctgagacgaa tctggtctta 895741 cttggctgaa agaaaaggac tgctcatact tgtcatgcta atggttgtca tcagcgccat 895801 attcggactc cttggtccct ttgtgatcgg aaaggccatc gaccatttta tcgtcgggaa 895861 aacggtcagc ggcttgattc ctgttttgct tcttctgctc gctatctata tcattcagtc 895921 cctgtcgctt tggtttcaaa actattggat gattacgatc tcgcagggca cggttttcag 895981 aatgagaagc gaattgttca cccatctgca tgagctgccg attccatttt ttgataaaca 896041 gcggcacggc gagctgatga gccgggtgac gaatgacatc gaaaatgtca gttctacctt 896101 aaacacgtca gtcattcaaa ttttgtcaag tgtgatcacc tttgtcggga cgattgcggt 896161 gatgctgtac atgagcccgc tccttacttt gattacgctg accattattc cggtgatggc 896221 agcgagcctg aaatggatca ccaaccgaac gggaaagctg tttaaagaac agcagaaaaa 896281 ccttggtgat ctgaatgggt atattgagga atctgtttca ggcgcaaagg tcatcaaagc 896341 atattcacgt gagaagcaga ttactgctga attcctcgaa aaaaacgctg cactcaagac 896401 gtcgggcttt tgggcgcaga cgatttccgg gtttattccg aaggtcatga actctttgaa 896461 taacttaagc tttacaatga ttgcggcaat cggcggtttg tttgcgctga aaggctggat 896521 ctcgatcggc tccatcgttg tctttgccga gtattcaaga caatttacac gccctttaaa 896581 cgatctggcc aaccagttta atacgatgct gtccgcaatc gccggcgctg aacgggtgtt 896641 tgacgtgctt gatgaaaaag aagagcgcga ggatgaaaag aacgccgtgc atcagcccat 896701 ccaaacaggc agcattgaat tccgggatgt gtccttcggt tacgataaag ggcagcagac 896761 actgaagcat ttacagttta ccgtgcctgc ggggcagtcc atcgcgtttg taggaccgac 896821 gggggcgggg aagacaaccg tcactaacct tctcgcccgt ttttacgagc ctaacgatgg 896881 aaaaatttta atcgatggta cagatattaa aacccttact agagcaagcc taagaaaaaa 896941 catggggttt gttcttcagg attctttctt atttcaggga acgatcagag aaaacattcg 897001 ctacggcagg cttgatgctt ctgatcagga agtcgaagcc gctgcaaaaa cagcgaatgc 897061 ccatagtttt attgaaaggc tgccaaaagg gtatgacacc gtactgacgc aaaacggttc 897121 gggcatcagt caagggcaga agcagttgat ttctatagcg agggcggtgc ttgccgatcc 897181 ggttcttctc attttggatg aagcgacaag caacattgat accgttacag aagtcaacat 897241 tcaagaagcg ctcgcccgtt taatggaagg aagaacaagc gtcatcattg cccacaggct 897301 gaacaccatt caaagagcgg accagattgt ggtgctaaaa aacggtgaaa tgattgaaaa 897361 aggcagccat gacgagctga ttcggcaaaa aggattttac agtgacttat atgaaagcca 897421 atttgagaaa tagacctttg tcctgcacag aggtcttttt ttgttacagt tttatagtac 897481 ttttatttca ttttcgtaaa atgtaacaaa attacttgac gtaaacaagt tatgtatata 897541 tactagctta cattaagtaa gtgataacat ttatcaagga ggataaaatg aataaatcat 897601 ttgaaattgg cacattactt ttaagagtta ttacaggtat tatctttttt gttcacggtt 897661 tatcaaagtt tcagggaatg gagggcacca tccaattttt cggcagcata ggccttccaa 897721 gctttatggc gtatgtcatc gcagcgattg aactgattgg cggagtgctt gtcttcttcg 897781 gattggctac acgtattgtc ggtgtactgt tcgctcttac actgatcggc gccatcatca 897841 ctgttaagct gaaagcgcca ttcatgggca atgcagaatt tgattacctt ctgcttttga 897901 catccattca cctggcgctt actggaagtc gattcctggc gctggaccca tttgtgttta 897961 aaggaaaaaa gaacggaaac gtttcagcat aagaaaagag gcatgcagca tgaccagcat 898021 tcatgaggat acacacattg gctatgccaa actcacaatt cgcagtctgg agcgttcgct 898081 tcagttctac tgtaacgtca tcggttttca agtcttaaaa aagacggacc gccaagcgga 898141 attaacggct gacgggaaac gcgtactgct tattcttgaa gaaaatccga gcgctgtcgt 898201 cttgcctgaa cggtctgtga caggccttta tcactttgcg attcttcttc cggacaggaa 898261 agaacttggg atcgcgctcg cccgcctgat tgaacacggc attgctatcg gacatggaga 898321 ccatgctgtc agcgaagcgc tctacctgtc tgatcctgac ggaaacggca ttgaaatgta 898381 cgctgaccgc ccccgcagca cgtggcagcg tgatcgggaa ggaaactacg tcatgacgac 898441 aaccgctgtt gacattgagg gccttctgga agaggcagga gatgagcgga aaacatcgct 898501 tccgaacgat acaatcatcg gacacattca tctgcatgtc agtgatttga aagaagcaaa 898561 ggcgttttat acagatgtac tgggctttga cattgtcgga aactatgcgg gcatgtccgc 898621 cctcttcgtt tcagccgggg ggtaccacca tcatatcggc ttaaacattt gggcgggaag 898681 aaatgcgccg cctaaaccga caaatgccag cggactagat tattatactg ttgtcctgcc 898741 ccaccaagag gagctggatt tggtggcaaa ccgagtcaaa catgccgggt attcgattga 898801 agagacggaa aacagctttc gtgtgaaaga ccctgtttcc ggcgcctata ttacatttgt 898861 gatttaactg caatcccctt gccgaaataa cggcaggggg attttttatt tttgtccgcc 898921 ttgttatgat gagagaacca acttgttagg aggcgtttac atggaactca accaccttgt 898981 gacgggcaaa atagcattaa atcaatatgt gcatcgctta gagcaaaagg atgtttcatt 899041 ttacgtccac tactggggag cgatgacgaa ccactataac acactgcttc ataagcattc 899101 cttttatgaa atttgttacg tggtaagagg tgaaggatat taccttgaag gcgatcgtac 899161 atatccgctt cgtgaacaga cgattttttt gtcaaagccg gagcatttgc accaaatcaa 899221 aagtgaaaca gggctgttcc ttttttacgt cgctttcgag ctgagcgagg atcagtcaag 899281 cgccgaatgg atcaaagtga tggaagaagt gaaacaaagc ccctttatca caatgcaatt 899341 gaaagatggc gaaccgccgg gcctgctttg gaaaacgtta atgctgcaag cagcgcaacc 899401 tgtcaatgct tttgacaaag agatcctatc tcatttgtcg catgcattga tcctgtcatt 899461 aatccaaacc tttctcccgt acgcccaacg cccgaaacaa aagcagccca ttcacacatc 899521 ttctgctttg ctgacagagg tgaaactgca cataaaagac aatctgtcac agccgttaaa 899581 gctgacggat gtcgctagcc actttcatat ctcagggagg catttatcac gtttatttgc 899641 agcagaactg ggcgtcagct actcagaatt tgtccaaaat gaaaaaataa acaaagctgc 899701 cgaactgctg aaatcaacga atttgtcgat taaagaaata gcggaagaaa tcggtttctc 899761 agtacattat ttcactcgcg tcttttccgc taaaatcggc agctctccag ggcttttccg 899821 ctccctttat aaagactcaa aaatgaccgc atttcaaatc aataaacctt ttcaaaaaat 899881 cgaacaggcc aagccgcacg aataagatgt cctgaaatga caaaacaatg tcttcatatg 899941 ataaagacgc gagaaatctc gttgtcttat aatcttttta gaaagcggtt acaacaaggg 900001 gtattgctga aggagggatg cattggctta tgcttggtgt cgggtgctct gccattcttg 900061 aaagaagggg aagaaagccg tgagtacaaa aaagaaagag gctgtaatag gaaaagaaag 900121 cttagctcat aaagggcttt tacgaacgat tacattggta tctacattcg gcggcctgtt 900181 gttcggttat gatacgggtg tcattaatgg ggcacttcct tttatggcaa ctgcaggtca 900241 gctgaatctt acacctgtta cagaaggact ggttgcgagt tccctgcttc tcggggcagc 900301 cttcggggcg atgtttggag gacgtctgtc cgatcggcac ggccgccgaa aaacgatcct 900361 ttatttagcc ttactcttca tcgcagccac acttggctgt accttttcac caaacgcgtc 900421 cgtgatgatt gcctttcgtt ttctgcttgg actggcggtt ggctgcgctt ctgtaacggt 900481 tccaaccttt ttagcggaaa tttcgccggc agaacgcagg ggacgaatcg tgacacaaaa 900541 tgaactgatg atcgtaattg gccagcttct ggcatacacc tttaacgcca ttattggcag 900601 cacaatgggg gagagcgcaa atgtatggcg gtatatgctg gtcatcgcga cacttccggc 900661 tgttgtgtta tggttcggaa tgctcatcgt gcctgaaagc ccgcgctggc tggcagctaa 900721 aggcagaatg ggtgacgccc tgcgggtgct tcggcaaatc cgtgaagaca gtcaggcaca 900781 gcaggaaata aaagaaatca aacatgcgat tgagggcaca gcaaaaaagg ccggctttca 900841 tgattttcaa gagccgtgga taaggcgcat tctattcatt gggattggaa tcgccatcgt 900901 acagcaaatt accggtgtca attcgattat gtactatggg acagaaattc tgagagaagc 900961 cggttttcaa acagaagctg cattaatcgg caatattgca aacggtgtta tttcagttat 901021 tgcggtcatt tttgggatat ggcttctcgg caaagtccgt cgccggccca tgctgatcat 901081 cggacagatt ggcacgatga cagcccttct gctgatcggg attttatcca ttgtccttga 901141 aggaacaccc gccctgccgt atgttgtgct gagtttgacc attttgtttc ttgcgtttca 901201 gcagactgcc atttctacgg tgacgtggct gatgctctcg gaaatctttc ctatgcatgt 901261 gcgggggctt ggcatgggga tcagcacctt ctgcttgtgg acagctaact ttctcattgg 901321 attcaccttt cccattttgc tcaatcatat tgggatgtcg gcgacatttt ttatctttgt 901381 cgctatgaat atcctagcga ttctatttgt gaaaaaatat gtgcctgaga caaaagggcg 901441 gtcacttgaa cagcttgagc attcctttcg ccagtatggc cgccgcgctg atcaggaaat 901501 ccaaaatcaa acaactcact tatcgtaacc tgagatacca ggaggaatct atcaatgaaa 901561 ctatcttatg taacagacag cctagggcat ttgccttttg aagacatgct caattttgcc 901621 gcaaagcttg ggatcgatac acttgaaatg acaaccgggg gctggtcgcc ggcacctcac 901681 ttgaatcttg atgaattgct gcaaagcagc gaaaaaagaa aagaattttc acaagcgctg 901741 gaaaagcgga acatgacact ttgcgcatta aactgctcgg ggaacccttt agatccgggt 901801 gaattgggca aatcgcacag agacataact gacaaaacga tggagctggc tggattatta 901861 ggcgtcaaaa aagtgatcat gatgagcggt ttgccagccg gcggcccgga cgacaaagtg 901921 ccgaactgga tcacatacac agtaagctgg cctcccgttt taaaagatat cctcaactat 901981 caatgggaag acgttgcgat cccatattgg aagaagcttg tcaaaaaagc ggaggcctgc 902041 ggcgtgggga aaatagcgct tgagaacttc agctctcaat tagtctataa tcctgagact 902101 ctctttcggc tcagaaatgc agtcggcccg atggtcggtt tgaatcttga cccgagccat 902161 ttgttatgga tgggcgcaga cccgatcatc gcagcaaggg agctcggctc agccattcac 902221 catgtccatg ggaaagatgt cagaattgaa agatatttat cggcggtcaa cggactttta 902281 gaaacaaaag aagtgacaga tcctgcaaac cgggcgtgga attacgtagc tgtcggctgt 902341 ggacaggatt tacagtggtg gaaggaattt ttttcagttg taaaaatgat gggatatgaa 902401 ggtgaggttt ctttagaaat ggaggatctg acgatgtcac ctgaagcggg catccgtact 902461 tctgtagaag ctttaaaaca aaccatcagc caataggagg ttttcatgat gctaaatgga 902521 gaaagaatca tctctaagcc gcttcgctgg gcaatggtag gcggcgggcg gctcagccag 902581 gttggatata aacatcgtat tggagcgctg agagacaata ctgcttttca attaactgct 902641 ggcgcttttg atatcgatgc cgaaagagga aaagatttcg gggtgaacct tggagtggat 902701 gcggaacgct gttatcccaa ctatcaaacc atgtttgccg aggaagcgaa aagacaggat 902761 ggcatagagg tagtatcgat tgccactccg aacggcactc attatgagat ttgtaaggcg 902821 gcgcttgaag caggagtgca tgtcatctgt gaaaaaccgc tgttcttcac ttcagcagag 902881 gggcaggaaa tcaaagcgct cgcagagaaa aaagggaaaa ttgtcggcgt gacgtacggt 902941 ttttcaggca atcaaatgct tcttcaaatg cgtgcgatga ttgaacaagg aatgatcggc 903001 gatattcgcg tggttgactt gcagtacaca cacggttttt gtgcaacaga tgaaggtgaa 903061 aagataagcg ctgcacagaa atggcgtgtc gaccctgcga tcgccgggcc aagctttgtg 903121 ctgggcgatt tatctaccca cacgtattat atgtcacagc ttattatgcc aaagatgaaa 903181 attaaggagc tgctgtgtga ccgacagagc ttcgtcggca gccgcgcacc gctagaggat 903241 aatgcccatg tgctgatgca ttatgaaaat ggagcggtcg gaacgatgtg gacatcgtca 903301 atcaatgccg gatgtatgga tggccataga atccggattg tcggctcaaa ggcaagcatt 903361 gagtggtggg acagcaagcc aaatgaactg acgtatgaag tgcagggaga gccgggccag 903421 acactcgttc gcggcatgcc gtatttagat gatgtttgca acgccgatga acgactgggc 903481 gccttacaca gcgaagggct gtccgaagca tgggccaata tttatcttaa atttgccatt 903541 gcgatagacg ccaaaaaccg tgaagatgaa gaaatcttga acaacttggt ttatcctgac 903601 attgatgcag ggatcgaggg cattcgctgg attgagaact gcgtgcgctc ggcaaaccaa 903661 gggtcagttt gggttgaatt taaataaatg agggaatgcg ccgcatatga cataaagttc 903721 atatgcggtt tttattttcc agaaactcct gtcaaaaatg ccctgaggca ggtatgataa 903781 gaagggaatt gggtatcggg agtgatgagc gtgaaagctc ttttttttac gagaatgttc 903841 accttgatgg tgagctgttt aatgtatctg tccattgtga aagaggataa ctggtttgga 903901 tatgtattta tagcagcagg tgctgccatg tatgcagcca atcatgtttt gctgacaaaa 903961 gagacaaatg ccatctggtt ctgcctgatt gatattgcaa tcggcttttc gttcggattt 904021 atctttcccg gcacaggttt gttcattatt atgctttgtc cggttgcggt cgcctttttt 904081 ctgcgggggt ttcctaaaag aacagcatgg tctgtcttat gtctttcctc tattttattt 904141 ttgaccgtcc tcatccgtac atatgcgatg ttcggcaatg aatttgtcat tgatcatttg 904201 actagcatga cattcgttgt cttctgcggt gtcgtgggca aattaatccg caagctgttg 904261 gatgcgcagg atacggcaaa acagcagttt caggaactga cggagtccca tctggcgctg 904321 tctgctgcac atcaggagct ccatttatat gcgaagcagg ttgaagagct gactgccatt 904381 tacgagcgga acagaatggc gcgtgaaatc catgatacag tggggcataa aatgacggcc 904441 cttctcgtcc agctgcagct tttgcgtgaa tggcaaaaaa gagacagcca aaaagcggat 904501 gagacagtag gtgtctgtga aacacttgcc cgtgaagcgc ttgatgatgt ccgcttatca 904561 gtacgcactc tgcaaactga aaacgatcct tcgctaatcg aatcgctgaa acagctgaca 904621 gaggactttt gcaaaaatgc aggagtcaca acagaatttg cggtcagcgg tgatcctgca 904681 atcatcccgc tgtctctcca tccgaccctg atcagaacgg tgcaggaagc actgaccaat 904741 gccaaacggc acggcggcgc cgcagcctgt tcgatacagc ttgcctgcac aacggacagc 904801 atcagccttg tcattaagga tgacggcaaa ggcaatcctg aggcagcact tggttttggt 904861 ctcttgaata tgaaaaagcg ggcagcggag catggcggaa tgatccgctt tgaaagcgaa 904921 cgggatcaag gatttactgt aaatgcagaa ttttcacttg ccaataaaaa atggagcttc 904981 gggcccgtgc agcaaaagga gagtttatca tgattaagat catcattacc gacgatcagg 905041 atatcgtcag agaagggctg gcatccctgc tccagctccg agaagagctc gatgtgatcg 905101 caacggcgcg aaacggacag gaagccttcg aaaaggcgaa agagctggag ccggatatcg 905161 tgttaatgga catccgcatg ccggtttcca acggggtgga gggaacaaaa ttaatcacaa 905221 gctcgctgcc aagcgtaaag gttttgatgc tgacaacctt taaggattca gcgctgattg 905281 ctgaagcgct tgaagaggga gcaagcgggt atctgctgaa ggatatgtct gcagatacga 905341 ttgtaaaagc agtgatgact gttcattctg gcggaatggt gcttccgccg gaattgactg 905401 cccaaatgct gaatgaatgg aagcgtgaaa aacagctgaa aggaataaat gagatagaaa 905461 aacctaacga gctgctcgac ctgaccgagc gcgaaatcga agttctggct gagctgggat 905521 acgggctgaa taacaaagaa attgccgaaa agctttacat tacagaaggc acagtcaaaa 905581 accacgtttc aaatattatc agcaagctgg ctgtcaggga cagaacccaa gccgccattt 905641 actcggtcag atatggtgta tctgtctttt gacatatgac gttttgcata tacgcttctc 905701 tgaaaaggcc ttttacaggc ctttttttca tgccctatgt tctatctgcc gctacatgcc 905761 gcacgccttt ctttcttcta caatggcaat ggatcaaaaa aaggagtgag acgacgtgct 905821 gcaagcagaa aacatcaaaa aggcatacgg aaaaaaaaca atcgtgaaag gcatttcttt 905881 ttccctcaaa aagggggagt cgttcggtct gctcgggcct aacggtgcgg ggaaatccac 905941 aaccatctcg atgatttccg gccttgtgcc gcatgacagc gggaacatca cggtgggcgg 906001 ctatgttatc ggaaaagaaa cggccaaagc gaaacaaaaa atcggcattg ttccgcagga 906061 aattgcatta tatccgacgc tgacggctca tgagaatctt atgttttggg ggaaaatgta 906121 cggacttacg cacggtgagg ccaaaaaaag agcggctgag gtccttgaat atgtcggtct 906181 gactgagcgg gctaaagata agattgaaac attttccggg gggatgaaac gaagaatcaa 906241 catcggtgcg gctttaatgc ataagcccga gctgctgatt atggatgaac cgactgtcgg 906301 tattgaccct caatcgagaa atcacatttt agaaacggtc aaacagctca acgaaacggg 906361 catgacggtg atctatacga gtcattacat ggaagaagtt gagtttttat gcgaccggat 906421 cgggataatt gatcaggggg aaatgattgc gattggcaca aaaactgatt tgtgcagccg 906481 ccttgggggc gataccatca ttcagctcac ggtcagcggg atcaatgaag cgtttcttgt 906541 ggcgatccga tctctggccc atgtgaatga tgtaacagta catgaattag agctcaaaat 906601 tgacatttct gcggctcatc atgagaaagt cgtcacaagc ctgcttgctg aagccactgc 906661 tcatcatata aacctgctgt ctcttcaggt gcaggaaccg aatctggagc gcctgtttct 906721 gaatctgacc ggccgcacgt tgcgggattg aggagggacg gcaatgaaaa aaagcatatg 906781 gatcgcatgg aaagatgtga aaatcagaat cacggacaga aaagggttta tgatgcttat 906841 cctaatgccg ctcatcctaa cctgtatttt aggcgcagcg ctcggatcag ttgttgacgg 906901 aggcagccgg attgatgata tcaaagtcgg ctacattcaa tcagaccagt cagatacagc 906961 aaacatgttt acaaaagatg ttctcaaaaa aatgaagtcg ataaaggtca caaaagtcgg 907021 cagcaaagac aagatgaaaa aactgattga tgaaaagaaa atcgatgtag gcatcgttat 907081 cccgaaccat tgggaagccg gcaaaacctc agctgttgtt aatgccgctc ctgatcaaac 907141 attgaaaagt tccatcattg aaacagctgc aagctcattt atagagcaat ataaagcggt 907201 aaaggaagcc gcgtcaggct caatggacta catcagtaaa acggaagctg taaagcaagg 907261 aaaacttgac cctgcacagt ttgcagaaaa gctggcaaag acgctagaaa aagaaacagg 907321 tgacaagctt actattgcgg aaaaatctgt cggcagcaaa gccgttacca gttttcaata 907381 ctattcggcg gcaatgcttt gcatgtttat gctgtttcat atcacagtcg gggcgaaatc 907441 atttttacag gaaaaggata cggagacgct tgccagaatg ctgatgacgc ctgcgcaaaa 907501 atccgtcatt ctcttcggaa aatggcttgg gacgtatctg tttgccatca tacaattttt 907561 catatttctg atcgtcacaa tcaacgtatt tggtgtggac tggggcggta atctgctgtt 907621 agtgagtgta ctcgggcttt cttacgccgc agctgtatct ggtatttcaa tgctgcttgc 907681 gtcgtgcatc agcgatatga aaactgcaga tgcgataggc ggcttcggca ttcaattgct 907741 tgcggttctc ggcgggtcca tgctgccgct gtaccaattt ccggacgtct tgcagtctgt 907801 atccaaagcg gtgccaaatc gctgggcgct tgacggcttt ctttctttaa tggaaggggg 907861 aggctgggct gaccttcaaa agcctgtgct tctttttgcg gcgatcggct tttgttcact 907921 tgtaattggt atcagacggc ttcatacaag ataaggaggt acaaaaggtg aaaaaaattc 907981 tagccatttg cggcattgag ctttctctca tttttaagaa gccacagaac tatttgatca 908041 tgtttgctgc cccgcttttg cttacctttg tatttgggag tatgctcagc ggcaatgatg 908101 ataaggtgcg gcttgcaatc gttgatcagg acgatacgat tctctcacag cattatattc 908161 ggcagctgaa ggcacacgat gatatgtatg tattcgaaaa catgtctgaa agcaaagcgt 908221 cagaaaagct gaaacaaaag aaaattgccg ggatcatcgt catttcccgc tcgttccaga 908281 cacagctgga aaaaggcaaa catcctgagc tgattttccg tcacggccct gagctgtcgg 908341 aagcgccgat ggtcaaacaa tatgcagaaa gcgcattggc aacgctcaat attcaggtga 908401 ccgcggcaaa aacggcatct cagacagcgg gagagaactg gaaggcggcg tataaaacgg 908461 ttttcgccaa aaaacatgaa gatatagttc cggctgtaac acgacagacg ctcagtgata 908521 aaaaagaggg tgcggaagca agtgacacag cctccagagc agcagggttt tccatcctgt 908581 ttgtcatgct gaccatgatg ggagcggctg gaaccatttt agaagcaaga aaaaacggcg 908641 tatggtccag attgcttaca gcctctgtca gccgagccga aatcggtgct gggtatgtgc 908701 tgtccttctt tgtcattggc tggattcaat ttggaatatt gcttctttcc acccattggc 908761 tgtttggcat caactggggg aatccggctg cagttattgt attagtgtca ctttttctat 908821 tgaccgttgt cggcattgga ttgatgattg cggccaacgt cagaacgcca gaacagcagc 908881 ttgcgttcgg caacttgttt gtcatcgcaa catgtatggt gagcgggatg tattggccga 908941 tcgacattga accgaaattt atgcaatcca tcgctgaatt tcttccgcaa aagtgggcga 909001 tgagcgggtt gacagagatt atcgctaacg gtgcccgcgt cacagatatt ctcggaatct 909061 gcggcatttt gcttgcattt gctgcgatca ctttcgcagc ggggctgaaa gcgctccgag 909121 cctaaaaaac atctgccgtt taggcagatg tttttttgca tgtgggtaca ttcgtatggg 909181 tgcagcctga actgcggtta atccttatct atcatagcta aaattgattc cagccaagaa 909241 acgtaatttt tctcccgctc cagcgctttc gttagcacaa gatagtggcc gaagtccggt 909301 gaagaaaatg acatcggctc tgctgaagcc ataagctttt catagcttcc ctgtaagtca 909361 gaaagcttgg cctggcgttt ttgcagctgg tctttgaaca aatcagaagc ctcctggcgc 909421 gatagacaag aaatgaaata agccttcagc ataaattcat ccttcaccgt ctcgggtatc 909481 ggctggtggc ggatcagcca gtcatgcagc tcctgctttc cgctgtctgt cagggtgtac 909541 atctttttct ccagctttgt gccctgaatc gttgtccgga acgtgataaa tccttcatcc 909601 gtcagctttt tgagctcagg gtaaatctgg ctgtgcttgg cgctccaaaa ctggccgagc 909661 tcctctttaa aataactcgt aatatcgtat ccactcaatt cgccttttcg caaaagccct 909721 aatatggcgt attttaatac tctcatgcta tcctccgtgt ctggctgttt cgcaaaacag 909781 atgagccggt gctcaactgt gattctaact gcctattccc cttattatag aaaagggagg 909841 aagggaacac aaccgggctc tttggaaatg aagataaaag gtttgtcaga aggtatccga 909901 tttatctccg tcaatataaa agagatttaa atttaatttt cagaaaaaat agtaacgata 909961 ttgatttttt atatataata ggaaattggt ggtatgaaaa ttttttgggg gaataaacgt 910021 gaaaaaagta cttatggcat tcattatttg tttatcgctg attctatctg ttttagccgc 910081 tccgccgtct ggcgcaaaag ctgagtcagt acataatcct gtcgttcttg ttcatggaat 910141 aagtggtgca tcatacaact ttttcgctat taaaaactac ttaatttctc aaggctggca 910201 aagcaacaaa ctgtacgcaa ttgattttta tgataaaaca ggaaacaacc taaataacgg 910261 cccgcagctt gcttcatatg ttgaccgtgt tttaaaagag actggggcaa aaaaagtaga 910321 tattgtggct catagtatgg gaggcgccaa tacgctgtac tatattaaat atttaggcgg 910381 gggcaataag attcaaaatg tcgtaacgct tggaggggct aatggtttag tgtcatcaac 910441 cgcgctgccg ggcacagacc ctaatcaaaa gatcctctat acatctattt acagtctcaa 910501 tgatcaaatt gtcatcaata gcttgtctcg gttacaagga gcgcgaaaca tccagcttta 910561 tggcatcggt catattggct tgctttctaa tagccaagtg aacggctata tcaaagaagg 910621 gctgaatggc ggaggcctca atacaaatta atatcttcaa aaaacaacct gctgtctccg 910681 ttacagtggg ttttttcgtc tgagaaagcc atagggtctt atgaccttag tctatcatgc 910741 atacgtcaat ttatgacatc aggcactttt tcaaatagag cggacatgtt aaggtacaac 910801 catcgatttc tatcaatttg aaataaaagg agcgctgtta tgcaaattaa agaaattttt 910861 atgatccgct gcatttcgtg cttaagtgtc gtcttgctcc atatcatttc aatggtcctg 910921 atgcttcagg cagaagctct tgcagatatt tctcacactg ttgattcttt ccgcacactc 910981 ctgatgttca gcacgcccgc ttttattttc atctctgaat ttttactggc ccgttcttat 911041 cctgatgggg tgcctgacgg ttttttaaag aagcggggaa aagtgatttt tgttcctttt 911101 ttatttatcg cagccatcga tgcgctgctg atgaccagtg cgatgggggg agaggtaacc 911161 tttctcgcgt ttgtgcaaaa atatctggcg aacgtattct taggaaactt tatcggatac 911221 ttcattctcg tcatctttca attttacatg ctgcatatga tgtttcatga gtatttgaaa 911281 aaagcatcgc cgaaatgggt gctgtctatc tcatttgtgg tgacagccgc ttatttaggc 911341 tatttctccg cagccagccc ggctcctgct tctgaagagg gaggggcatt tccgttcttc 911401 tgggttccgt tcgcaggctg gcttttctac ttttgtctag cctactattg cggaaaagaa 911461 tacaagcgtt ttttagcgct gctgaaccaa taccgctggg tggtgtacgg cgccgcaatt 911521 gcttctgggg cgctggttgt cactgtttct tatgtcggtg aaatcggcat gatcagctcg 911581 aagcggcctg atatcatgct gtattcaaca agcatgattt tcctgtgttt tcatttgttt 911641 tccaaaatga agcatgtgcc gaaaatcatg atgtttatca gcaactattc cttttcgatt 911701 tatctgcttc atgcctattt tatgattata ggctacgtgt tgcttttgaa tatgcccgaa 911761 attcctgccg taccggctgt tctcctgttg tttgccgtgt gcacagccgg cccgattatg 911821 acctcatggg cgctgaataa gttcaaatac gggtatttat ttgtggggaa aatttatcag 911881 ccaaaacaga agaaggtaac agtcgaagtg cgtgatcacg cagggtgaaa aacaagcggc 911941 aggagggctc ctgccgcgtt tctttacttc tcatccgctt gcagaactgt ttttaaatat 912001 agttttgcag actcagcaag tccagataca tcagcctttt cttcatcgaa atacagggcg 912061 ttttgaatga tgccgtcatt catattgagg aaaaacttgg cgatagtcgc aagaggctga 912121 accggctgaa actctccctg atcgatccct ttttgcaata gccttgaaaa cctttccaca 912181 aaaagatcat accttttctc caaatactgc cgccgttctt cattgcgcca agctgtcact 912241 aaatattcaa attgcaccgg cgccagcgta tctgctacat ctcgcaggcc ctcagtcagt 912301 tcatccaaat agctggaaat ggaggcccaa acactttggt gttcagctga tttatcaagc 912361 tttcggagtc cttcatccag ccctgtttca ataatgcggc gaaacatctc ctcagtgctt 912421 gaaaaataaa gatagacacc gccccggctg aaacctgact cttctacaac atccttcatc 912481 gtcgttaatt cgaatccttt tcgtttaaaa accgttttgg cagcctctaa aatctctgcc 912541 tgccgtttat ccttgtgctc ctttgttact tttggtgaca agatatcgcc tgctttctgc 912601 aattttctta cctataagtg taatcaaccc aatcatgatc agcaagcagc cacagacaag 912661 aaaagcaagt gatacaccga tccattccgc cagcacgccc ccgcccgcca tgccgaggat 912721 agaggcgagg gttgtcgcac tctgaatagc gccgaacacc ctaccgctgt aatcgacagg 912781 cactgttgtt tgcacgagaa tctgaaatgg aatatggacg aggccgaaag ccgcccccat 912841 gatgaaaaaa gcaaatataa agagagtgat gccggcaatt cccataccgc ttaggaatgg 912901 cgcacctcca gttgctagtc caagaagaag ggttccagct gagaaataaa gcaaataaga 912961 agtgattcgc cgtctgccgg taatggccgc tgtaaggagc atcccggctc cgcttacggc 913021 catgcaccag cctgccagct cgggcggagc tcctgaaaag gagcggataa gaataatcgc 913081 ttgggaatca ccaatctgca aaacaaagag aacgacacaa gctgttagta agcctgttaa 913141 tagaagcggc atccgtttca aaaactgaag gccttccttg atagaagtaa gtgctgctgt 913201 tttttcttga ggtgtattgg ctttttgtaa aaaagcatct ctgggaagga aaaacaaaat 913261 gacagcggaa agaaagaagg cgccggcgtt tatataaaaa acagagtgta tcgagaaagc 913321 agcgatcagc gtgccgccaa gggcagggcc gaagattttt gagctgttat caatgatgct 913381 gctgacggaa acggcctgct gaatgtgtgc ttccggagcc aattccttaa gctttccgtt 913441 tttagcaggt aaaaaaagtg aagaaaaaca gctctgaacg gatagcaata cgtaaagctg 913501 ccaaagctca ctgacataaa cgcagctgat aacagtgagg gcacggccga tttcagatag 913561 aaacatgatc gtttttctgt caaaacggtc ggcaagcaga cccgatacag gtccgagtac 913621 aatgacaggc aaagcaaacg acatcattaa aagcgacata tctaatggag aagcatgaag 913681 ctgaaaagcg gctaatgtta gcacggccaa aatgtgaagc cagtctccaa gtgaagaaat 913741 ggtttgcgag gctaacagtg tcatcagtcc tttttgattg cgaaacaacg gtttttccat 913801 gattcatcct cctgattatt aaaatgacac tagtgtcgtt tttaattgta tgggaaaaag 913861 acacaatata caatcttttt cttgtaaaat aaaggagaag attgaataga agggagaaca 913921 ttcatgacat cagtcaatct aagctaccca ataggagaat acaagccgag ggaatccata 913981 tcgaaggagc aaaaagataa atggattcaa gtacttgaag aagtgccggc aaaattgaag 914041 caagctgtag aggtcatgac ggacagccag cttgacacac cgtaccggga cggtggatgg 914101 accgttcggc aagttgttca tcatctggct gacagtcata tgaacagcta tattcgtttt 914161 aaattgagct tgacggaaga gacaccggct atccgtccgt atgatgaaaa agcatggtcg 914221 gagctaaaag actcgaaaac ggcagatccg agcggctcac tcgcgctttt gcaggagctt 914281 cacggaagat ggacggctct gctccgcacc ctgacggatc agcaatttaa gcgcggattt 914341 tatcaccctg atacaaagga gatcattacc ctggagaacg cgctcggcct gtatgtctgg 914401 cactcacatc accatatcgc tcatattacg gagctttcca gacggatggg gtggtcttaa 914461 cgcttttgcc ggcggaaagc cggaatactg atagcagcaa tcaccagaag tgagaccaca 914521 gcagccgctg catataaatg atcatagccg ctggcgacac tcgcatgaat ggcgtcgctt 914581 atcgcggttt tgacttcagg aacgggaatg cgttcgattt gttcttgtaa agaagaaact 914641 tcagaactgt cgatctccgg aatcatctgc atcgcctttt ctgaatatcc gctgtccgat 914701 aagcggctgt tgatctcatc acctatttgg tcaaacccgg ctgtgataaa acctgcataa 914761 agagtaggcg ccaaggtcag tccaatttgc cttactaatg aaagcgtgcc aagagctgta 914821 cccttatttg tttttgccgc ttctgataca aggacgttca gcggagcgcc taacagaaag 914881 ccaaaaccga tcccagctgc cacacttgcg atcacaaact cccatttttc cgtgacccag 914941 agcggaaata aagcaaaccc cgcacatgag atgattcccg aaagaataac ggtttttaca 915001 ggaccttttt tgtcggtaag tgctccgcca agccaagcgc cgattccgga agccaacgca 915061 agcggtgtca tccaatagcc tgcttttgcg gcagggacac ccaaatactg ttcgacatat 915121 gacgggataa aaatgactgc cgccaagagc cccccggata acaaaccgat gataagcgtg 915181 cgctgaaaca tatggtttcg cagcagagaa tacgccaaaa tgggatcgcc tcctcgcatt 915241 tcaactctct tttcatacga gataagcgct gcaaaacaga gtatgccaaa aataatacat 915301 ccataaacct ccggattccc caagctgtgt aagagatttg ccccgtcaag attggtcatg 915361 ccgtacatca cagctaaaat cgacagggac aaaaggaaga ttccggccgc atcgaggcgc 915421 ttagcctcag gtgcttttgt ttccgcgata aaacatgcgc cgaaaacaac caatagcacg 915481 gcaatcggca aattaatcaa aaatagccaa tgccaagacc cggtccaatc aagcagaaag 915541 cttccgatat ttggcccgag cacagcggcc atcccgttca ttgcgccaag cagcccaagc 915601 gccttcccct gtttttcctt tggaagggtc gcgagaatgt gagagctgcc gatgatgaaa 915661 atcccgccgc ctccaagcgc ctgaatcagc cgcgatatca gaaagagcgg gaagctttgg 915721 ctcaaagcaa caagcaaaga accaagtccg aacaggcaaa cctcaatgag aaagagtttt 915781 tttctgccgt agcggtcgga aagttttccg acgattggca cactgacgct aagaccgagc 915841 gtataaaggg taatgcccca tgatccccag gaaggggaaa cggaaaacga ctcgtttatc 915901 gttgttaaag cagccgaaat aattccgtta tctaaagcag ccataaacac gccaatcgta 915961 aacaggctga ttgcccactt ttggcttttc tgctctgtta atgcttcaga cattttcgtc 916021 aactcctttt agttcacttg aaatatatta ttcattttaa atgaactaaa tgtcaaataa 916081 aaaaagcctg ctcccgcagt ttgcggatga cagacttact gatttattct tttttcgcat 916141 tctctaatgc tcttgaaagg atagacagcc cttcgtaaac agcctgcttt tcttcagggg 916201 acagcagctc taatgaacgc ttcaatttca ggtggccctt ttcatacaaa ccccggaaaa 916261 tctttttcgc attctctgtc aactgaacaa ctacagagcg gcggtcctct tcagaatgtg 916321 agcgtttgac aaatcctgat ttttcaagcc ggtcaagcag cccagttgta ttggacaggg 916381 aagcccccat tttttcagca atgtcgctca ctttcaatgt tccatggttg tttaatagca 916441 tcagcacctt catttgcggc atgctcatat ccagtttcat ccactcggac acatcaccga 916501 gcccggcgga cgttaagact ttcatataga gcacccatat ttcccgttcc tccgatgaaa 916561 gaatgttttc gtttaagact gttgtatcgt gtaaattata ttccatttca tcacttcctc 916621 atcattcact cctcttacca tattactcga ttttcactcc tgaaagaaag tgagcagaaa 916681 ccgcatgcgg gactttgtcc gaaaaataac ggtagtgtat aatgagttgg agattattgg 916741 gggagaggat cgaactagaa tatgattgga gagaccattg ctgattaaaa agaatgcttt 916801 atcaatatta aaaatcgttt ttcctattgc tgttttgcta tttgttattt atcaatcgaa 916861 aaaagaactg acaaatctgt cattcaaacg tacgctcatg gtcatcaacg gactggaacg 916921 aacggattta ttcatgcttg tgttgatcgg cttgctggct gttgcggcta tgtcgctgta 916981 tgattacgtc ctgaagtact cactgcgcct atcgatcaca aacggaaaag ttttcagggt 917041 ttcctggatc gccaattcat ttaataatgt gttgggattc ggcggtttag ccggagtcgg 917101 gttaagaatg atgttctata aggagcatac gaaagaccat aaggcactcg tgaaaggaat 917161 cgcctggctc acatcatcta tgctgctcgg attatctgtt ttcagcattt tcgttgctgc 917221 gagagtgctg ccagttgatg aagtgattca tgagaagcct tggctgtggg cggtcgttat 917281 cggttttgca ctgatattgc cgttatcttt agcggtgtcc aaaataaaag accgcaaagc 917341 tggggacgaa gagaatgcgg ataaagtgaa aaatccgatt ttcgcatata ttggagcttc 917401 agttgttgaa tggctcatgg ccgggaccgt catctatttt gctttgttcg ctatgggcat 917461 tcatgcagat atcaggtatg tgttcggggt gttcgtcatt gcggcgatcg gaggaatgat 917521 cagcctcgtg ccgggcggct tcggctcgtt tgacctttta tttttgctgg ggatggagca 917581 gcttggctat catcaagagg ccatcgttac ttctattgtg ttgtacaggc tcgcctactc 917641 atttatccca tttatcttgg gactgttctt tgccgccggc gacctgacgg aaaatacaat 917701 gaagcggctc gaaacgaacc cgcgcatcgc accggcaatt gagacgacaa acgttctgct 917761 tgttgttcag cgtgcggtat tagtgagaat tttgcaaggc tcgctttccc ttattgtgtt 917821 cgtagcaggt ctgattgtct tggcctcagt ttccttgccg attgacaggc tgacggttat 917881 accgcacatt ccgcgcccgg cgcttttgct gttcaacggc ctgtccttaa gctcagcgct 917941 cattctgctc attttgccga tcgagcttta taaacggaca aaacgttcct acacgatggc 918001 cattacagcg cttgtcggcg gctttgtgtt cagcttttta aaagggctta acatcagcgc 918061 gatattcgta ctgccgatga ttatcgtatt gcttgtgcta ttgaaaaaac aatttgtccg 918121 cgaacaggca tcctatacac tgggacaatt gatattcgct gtggcgctgt ttactgtggc 918181 gctctttaac tacaatctga tcgcgggctt tatttgggac cggatgaaga aggtgctgcg 918241 tcacgaatat ttcgtccaca gcacctcgca tattacacat gcaaccatca tggcgatcat 918301 cattgtgccg ctgttcttct tgatatttac agtggtctat cataagagaa cgaaaccgat 918361 cggagagaaa gctgaccctg agcgtcttgc tgcgtttctc aatgaaaaag gcggcaacgc 918421 gctgagccat cttggttttc ttggagataa gcggttttat ttttctagcg atggaaatgc 918481 actgcttctg tttgggaaaa tcgccagaag gctggtcgtg ctcggcgatc catctggcca 918541 aagagaatca ttcccgctcg tgctggaaga atttctgaac gaagcgcatc agaagggatt 918601 cagtgttttg ttctatcaaa ttgaacgaga ggacatggcg ctgtatcacg attttggcta 918661 caacttcttt aaattgggtg aggaagcata tgtagattta aatacattta ccttgactgg 918721 gaagaaaaaa gccggccttc gggcaatcaa taaccgcttt gagcgggagg agtatacttt 918781 ccatgtggat catcccccat tttctgatgc gtttttggag gagctgaagc aaatctcaga 918841 cgaatggctc ggctcgaaaa aagagaaggg attctcgctc ggattttttg atccttccta 918901 tttacagaaa gcgccgatcg cctatatgaa aaatgcagaa ggagagatcg ttgcattcgc 918961 aaatgtcatg ccgatgtacc aggaaggaga gatatcggtc gatctgatgc gctatcgcgg 919021 cgacgctcca aatggcatta tggacgcatt gtttatccgt atgtttttat gggcaaagga 919081 agagggctgt acgtcattta atatggggat ggcacccttg gccaatgtcg gcactgcctt 919141 tacatccttc tggtccgaaa ggtttgccgc tgtcattttt aataatgtca gatacatgta 919201 cagtttcagc ggcctaagag cctttaaaga aaaatataaa ccggagtggc gagggaaata 919261 cttagcgtat cggaaaaaca gatctctttc tgtcaccatg ttcctcgtta cacgtctgat 919321 tggcaaaagc aaaaaagact ccgtctaata agacggagtc tttttttatt tcgtttttaa 919381 gaagtaggtt tcaatatcat caagcaggta gtttgcggct ttaattccgc ctgcggttgt 919441 ccatacgacg tcatcgactt catgtgcatt acctgacttc acggccttca ggtttttcca 919501 tagtgaactg cttgtccact gattggccca tttttcattt tcttttgcat tatcggcttt 919561 ataagtgaaa taaaacagca catcagcatc catatcagga atagattctt tactgtcggt 919621 tgagaacgta aattggtcct tttgtttctt aaacagttcc acttgttttt cagggcgttt 919681 gaagccaagc tggtctaaaa taatcccagg aaatgaatcg gtataataga ttcttgattc 919741 accggataaa aagcgtacga ctgaaacggt tttgtttgtc tggtcgccca gcttgttttt 919801 taaatcagaa acacgtttat caaaatcggc aatgacttcc ttgcctttgt ccgccttatt 919861 caccgcgttg gcgtatagag tcaggttatc cttccagttc ccggccaaag attcagcaaa 919921 aacagtcggc gcaatcgcat ttaactgatc ataaattttt tcctggcgca ctttgtttcc 919981 aataatcaaa tcaggcttta attctgcgat ggcttccaca ttcggttccg tttcaagacc 920041 gacgttttta acacctttca tgtcatcttt cagatagtca taccacgggt cgcccttcca 920101 tgactttacg gctccgaccg gcttaatgcc aagcgctaag agcgcctctg ttccttcatt 920161 agttaaaaca acaatccgtt ttggattggc ggggatgttg tctgatgtcc ccattgcatg 920221 tttgaccgtt cttgttttgc tgcttgacac ctcgctgttg cttgaacttt ctgaactatt 920281 acaggcagaa agtaccataa cggccattaa aaatacgaat agcatgctga tatgcttttt 920341 catctttttc ctcccaatat tgaaattcat tatcatttag atcataataa gcagtgttaa 920401 gagtgtcaat ccctaattga ggattattct caaaaacaaa cattacatag taaataacta 920461 ggagaattag atcatgatct gcaaaaaggc atcttcaaaa tggattgtgt tagtatgtct 920521 gattttcatt ttactgacgg ctgtctgcgc aagcgtcgtg tatggctata caggtacgtc 920581 atggagacag gtctatcagg cgtttacttc cttcaatgga acaaatgagc atgtcatcat 920641 caaggatgtc aggcttccgc gcgctttggt tgcgacagtc gtcggcgcct cgcttgcagc 920701 cgcgggcgct ctcatgcagg cgctcacaaa aaatccgctt gcgtcaccgg ggattttcgg 920761 gattaacgcc ggtgcaggtt tttttattgt tgccggatcg ttttttctgc atattcagtc 920821 acctcaggca ttagtatgga gctcgtttct gggggcagca tttaccgctg cgatcgtcta 920881 tgcagcaggc tcgcttggga gggaagggct gacgccaatc aaactgacgc tggcgggagc 920941 tgccatggca gccatgtttt cttctctgac acagggcttg ctgtctgtca acgaactcga 921001 gcttgcccag gtgctttttt ggctgactgg ctctgtgcag ggccggagtc tggatctgtt 921061 gatgacgatg tttccatatg cagcggcagc gctggtaatc tgcttctttc tcggccaaaa 921121 aattaatctc ctcgttatgg gagaagatgt ggcaaaagga ctcggccaaa aaacaggcct 921181 gctgaaattt gtgatggcgc tttgtgttgt catgcttgca gggtccgctg tcgccattgc 921241 cgggccgatt tcttttatcg gcatcattat tccgcatttt gcccgctttg tcgttggtaa 921301 tgattatcgc tgggttctgc cattttccgc tgttttgggt gccattttgc ttgtttgcgc 921361 ggatatcggt gcgcgatata tcattatgcc tcaggaagtt cctgtcgggg tcatgaccgc 921421 catcatcgga atgcctgtgt ttgtgtacat cgcaagaagg ggggcgaagc tatgaaactt 921481 cgttttggcg ttactgcggc tgaaaagaaa gcatggatcg tctttttggt tttactgggg 921541 ttaacagctg ctgtactcat cataagcgct ggtctcggac aaaggtttat tcctccctgg 921601 gatgtagcaa aaacattctt tggtgcaggt tccaagctgg atgaactgat gatcatgtcg 921661 ttccgcatgc caagaatttt gacggcttta tgcgccggtg tctgcttggc agcggcaggc 921721 gcgatattgc aggggctcgt cagaaaccct ctcgcatctc cggatattat cggaataaca 921781 ggaggagcgg cggtagcggt cgtgctttta atgatgttct tctcagaccg cagcagttca 921841 cttacgatca gtctgtcatg gcttccagca gccgcattta tcggcgcatc ggctgtcggg 921901 ctcatcgtct atttactggc atacaaaaat ggcgcctcca catttcggct ggtgcttatc 921961 ggaatcggat tttcaatgtc ggcgcaggcg atgactaccc tgttgatgat caaaggcccg 922021 atttaccgag catcacaagc caatgtgtat atcactgggt cagtttatgg gtcaaactgg 922081 cagcatgtaa aaatagctat tatcttatct gtcattctct tattcatttg ttttgtcgcg 922141 ctaaaaaata tgaatataca ggtgctgggt gaagatattg cggcgggtgc aggaagcgct 922201 gtgcagcgaa atcgtttttt cttgctcctt ttgagtacgg ctcttactgg ttgtgcagtt 922261 tcagttgccg gcacaatcgg ttttgtcggg ctgatggcgc cccatattgc aagacggctt 922321 gtcggctcat cttatggcgc gctgctccca gcgtcggcac ttattggagc tctgctcgtt 922381 ttaacagctg atatcgtcgg cagaacctta tttgctccgg tggaagtgcc ggccggcgtc 922441 tttacagcgg ctatcggcgc accttatttt atttatttgc tctataaaac aagaaattct 922501 taatcgttac acccattttc ttaaaaaaga aaatgggttt ttttgataat gactgaagat 922561 tcgtaattat ttttgctata ctgacagaga cattgataaa gaaagggcgg cagatgaatg 922621 aaagaagcag aggtattaaa atatgaagca tttacaagca gtcccggcaa aggaaacccc 922681 gcaggcgtcg ttttgcaggg agacgattat acggaagacg agatgcagat catagctgaa 922741 cgtgccgggt attcagaaac ctcctttatc cgaaaaagcg agtcggccga tcttgaactc 922801 cgttacttta cccctggaca cgaaatgaat ttgtgcggtc atgcgacagt tgcttctctt 922861 tacgcattat gtgagaaagg aatgctggag agcggtaaaa cgtacagcat ccaaacgaaa 922921 gcgggtatcc tgcctgtgaa gatttctgaa aaagatggcc gcattcatat cacgcttgaa 922981 caggcctctc cgcaattcaa accatttaca ggcgatcgga aaaaacttgc ggacgcactg 923041 ggtatcaccg atgaagattt tcatgaagac cttccgattg tgtttggcag cactgggata 923101 tggacagcca tcgttccgct taaatcattg gaggcttcca aaaaaatggt gccagataac 923161 aaacaatttc cggaagtgtt agttgatctg ccaaaagctt cagtccatcc gtttaccttt 923221 gaaaccgtcc atcccgacag cgacctgcac gggcgccact tttcatcccc gtattcggga 923281 acgattgaag accccgtgac cggcacagca tccggcgtga tgggggctta tatgaaacat 923341 tatggcaatg ccgagcagca taaatttatc attgaacaag ggcaggaaat tggaaaagac 923401 ggaaaagtgg agatcgaaat gaacgaagcc ggcggccatg tgaaagtgaa catgacagga 923461 acagccgttt actcagaaac ccgtattctt aaaatctaat acggatgatg gtttacaaaa 923521 agatgcactt tccgttatca ttatgaaatg ataatcattt tcaattgcat aggaaggtga 923581 gacggtatgc ctcaaaccga acaaatacat cagcattcag tactgaggga catcatacgc 923641 agcagaagat cgattcgaaa gtttaaacaa gagccagtac cttcagcagt cattcttgac 923701 atgcttgaaa cggcaaaata tgcgccaaat cacagagtga cagagccatg gagatttatt 923761 tacgtttcca gtgagacagg taaagcgaac ctcattaata catttgcagc gttctctaag 923821 aaatccaagc cggatatgac agaggaaaag cttcaaaatt tcaaaaacac acttgggcgc 923881 gttccgggat ttctcctcgt cgtgtttcag gaagatgaaa acgaaagagc gcgggacgac 923941 gattttgcgg caacaagctc gttgattcaa aatcttcagc ttctcgcttg ggaaaaagga 924001 atcggcatgg tttggaaaag cggaaaaatc ctttatgaca aagaagtcca tcaggccttt 924061 ggtttacagg ataatgagcg tttcgccgcc atcatacaaa caggttatcc tgacgaggcg 924121 ccggaagtga aaaaacgcac accgatccgc gaccgattca ctgaaatgta aaaaacccct 924181 tgtctcaaac ggagacaagg ggtttttcat taacgagatt tctttttcgc tctgttgtcg 924241 gctgctttcg cacgctcttg cgcttcgcgg tcatctgcat cagcaagctc ggttgaatat 924301 tcttcgtaaa cgccgtcagt ttcccttttt aaggcatcgg gaacttgtgg aagcttttgt 924361 ttgtttttat cacggttttt gtggatatga tttctgccca tatcaaattc cccctaaaaa 924421 gtgatatcaa acaaatatag tatttggttt taaggggcta tgtattccta cttccgctta 924481 gcagcttttt ccgctttttt aaattcgcct gaataaagaa cttcctgcat ttttttcagg 924541 ttggcgcctt gctggtgctt ctccctcttt ttttccataa aaaggacctc cttcaaccat 924601 gttattctta aggttgacgc ttcctgctgt ttttatacag tctttcggtc cgctatcagc 924661 tgtgagagtg caaattcaag atccgaatat gtaaaacgaa atccagaggt tatcgctttt 924721 ttcggaagag cgcgctgtcc tttcacaatc aaaagactca tttcacccaa tgcttttgat 924781 aaaaagaatt ccgggacggg gagccagtgc gggcggtgct tcacccgtgc aatcgttttt 924841 ccgaattgct tcatgtccac aggattgggc gcggtgacat tcattgggcc tgagatgccg 924901 gcgttttcca ccgcatatcg gatcatctgg gccgcatcct cgacatgaat ccatgacagc 924961 cactgccttc ccgttccgat cgttccgccg gccagaaact tataggggag aatcatgagc 925021 gggagagcgc ctttttctcc aagcatcacg ccaaatctcg cataaactgt ccggatgccc 925081 atcgcttcaa tatgctgtcc ttccttttcc cacaggtgtg cagtatggct gagaaaatcc 925141 tcatctgacg ttgcagaatc ctctgtgaaa gttttctcaa ggcttgtgcc gtaaatgccc 925201 acggcactgg cttggatcaa tgtcttcggc ttctccttct gtttctgaat aagccgctgc 925261 acttcacgcg tcgcattgat acggctggag agaatgtgct gcttcgtttt ttctgtccag 925321 cggccaaaaa tcgattttcc cgcaagattt atccagacat caatatgagg aagttcctgc 925381 tccggtgcgg ctccttccga cagccattgg acatatgtca tatttttttg ttcagtttcc 925441 cttgcgtttc ttgataaaat ataaacatgg tgtccctggc gggtaagaac gcctgtcaga 925501 tgctggccga gaaaaccggt tccgcccgtc attgcgatat tcatgaacat ctctcctcat 925561 cgttctaata aatatacttt acctcattgt aataaaagaa aacgcgtttc aggcctgaga 925621 agggagatta agatgccgtt tattacaaaa atatcaacgc aaaaaaagaa tacggaacgc 925681 ttcaatattt ttctggatga taaatacgcc ttcagcgtgg acgcggatgt gctcgtgaaa 925741 tttgagctca agaagggaaa agaactcgat gatcttgaca tcattgagat tcaatacggc 925801 gatgaagtga agaaaggctt caaccgtgcg cttgactttt tatcctatcg aatgcggtcg 925861 acgaaagagg tcgaggatca cttaaagaaa aaagaaacct cgccccccgt cattgcggaa 925921 gtcatccata ggcttaacga ttacaagtac ttaaacgacc aggaatttgc cgcagcctat 925981 gtcagcactc acaaaaaaac aaacggaaaa ggccctgatg ttttgttcag agagctaaga 926041 gcgaagggaa ttgatgacga tacaattaag gaggcgctaa gttccttttc ctttgaagat 926101 cagacaagag aagcggtcaa gcatgttgaa aagcttctca aaaaagataa aaagctttcg 926161 acgaaagaac tcaaacagcg cgcccagctg cagcttcagc gcaagggctt ctcatttgat 926221 gttatcagcg cggcgatgga tcagattgaa tatgaaaatg atgaagacac agagaaagaa 926281 gcgctgcgcc ttcacgcgga aaaagcgttt agaaaatacc gctatgacgg ctcatatgaa 926341 agcgccatga aggtcaaaca atttttattc cgcaaaggat tctcactcga tttaatcgag 926401 caattactgc aggaagagga gtactgaaat ggagaaacga tacagtcaaa tgacaccgca 926461 tgaactcaat accgaaatcg cattactttc tgaaaaagca agaaaagccg aacagcatgg 926521 aatcataaac gaactggcag tgctcgaacg gaaaattacg atggcaaaag catatttgct 926581 gaacccggaa gattactcac cgggagaaac atatcgtgtg gaaaacactg aggacgagtt 926641 taccatcagt tatttaaatg gcgttttcgc atggggatac aggacctctt cccctcagca 926701 agaggaagcg ctgccaatct cagtattgca agaaaaagaa taaagcgtaa caggaggctg 926761 atgatcagcc tctttttgtt tgcagcacat ttacacgaat tcttaaagaa aaaatcattg 926821 aattcacttg aaaaatcttt taagatgaaa ctcgttgttt tttaaaatca aaggaggcga 926881 tgacgttgag tatcaaaaac ccatctgtaa aatttattat atttgttctt atgatttgta 926941 cattttcaat cggctataca gaatacgcgg tgatgggtat tttgacgtcg attgccaatg 927001 actttcatat acaggtttca tccgcagggc ttcttgtcac ggcttatgcg gcaagcgttt 927061 gtttgacagg gccgctcgtc accatcattt ccgtcaagct tccgagaaag cctgtgcttc 927121 ttgggctgat ggcgatattt atcctttcca acctgatgag cgcactggcg ccgaattttg 927181 cggtattggc catttcaaga attttatctg cgtccattca cggcgctttc ttcgcgattg 927241 ccatggtatt cgcaagtgaa atggttccgc cggaaaagcg tgctgcagct gctgcttcaa 927301 tgaacggcgg actgacagtg gctctaatgc ttggtgttcc attcggctct tatctcggag 927361 atgtcctgaa ttggagagcg gtgttttcca tcattacggc acttggtgtc atcggatttt 927421 taggccttat ggctgccgtg ccgaacagaa aaccaaaagt gatcccaatg cttatgaatg 927481 agtggggtgt ttttaaacac aaacaagtgc tgttttcctt cgcgattacc attttaggct 927541 attccggtgt ctttatcgcc tacaccttta tcgaacccat tttgaggcat tcagccggat 927601 tcagcacggt tggcattaca ggtgctctct ttgcgtatgg attgggaggc gttgccggga 927661 atttctttgc tggaaaggta ccgctgcctt tgctgactcg gacgatgatc ggcgtaatga 927721 tcggtttaat cggtgttctg gctgtatttc cttacatcgc catttacccg gctgcagcca 927781 ttgtggcaac gttcctattc ggggcatgcg cattcggcac gccgcctctt ctgcaaacaa 927841 aggtcatttc ctcatctgag ggcggcacaa ccattgccgc agctgtcagc gtatcagcat 927901 ttaaccttgc caatgccctt ggtgcatgga tcggcggaat gattttaaac ggaacaggct 927961 cttattcctg gctgtttgca ggaggtgcgc ttatgaccgc atgcggactt gtgctttcta 928021 ccttcgcaca cttatcagaa aagaagagcg tctacgaata tcaagtcaat aaagggtaaa 928081 aaacagctgc agtgtatgca gctgttcttc tttaccgttt gcctgaggct ctcattcttt 928141 cttgaggatg ctgattgata gatccgtcag cacgctttga agcatagtcg tcctttgctc 928201 tcggttcacc ctgaaatttg ttttcgtttt cgtaaggaaa tcctttttct ttatttcgga 928261 ccatgtcata tccccctagg ttcgagatca aaaagttgcg tcttttcaga tgaagacgta 928321 aggttagtat atggagaaca ccacgtaata aagcgttatt tttttcctga agaaaggaga 928381 ctgcacacat gaatatgtac attgagaaac tgactaatct gcttctggaa aagaacgaga 928441 tgatcagcta tatacaggca aaaacgtggg tggaattgtt atggagcgat ttcgaagcaa 928501 cctacgcaaa agccggacac gcctatcaag gtgaaaaaat gactgaaaaa atcgtcacac 928561 aatggattga aaactatggc ggccagctcc acctttttca aagctcccgt aacgacgtga 928621 atgattactt aaatcaaagc agaggccttt tgcattaaaa acctgccgtt aacgaccggc 928681 aggttttttc attttcttaa aattacctta acaggaagaa atcataaaca aaacatgttt 928741 caccagcctg tcaatcaggg aataccactt atatcttgtc aaaatgcgag gaggagcttt 928801 atatgaaaaa gaaacaagta atgctcgctt taacagctgc cgcaggactg ggtttgacag 928861 cacttcattc cgctcccgca gcaaaagctg cgccccttca cgacatatct gtcagcatgc 928921 catcatccga tacttacatc ataaaagcag gaaagctgaa tgtccggact gagccaaatc 928981 atgaaggtga tattctcggc actgtatcat cagaacaaaa ggtaaaagtc gataggttcg 929041 taaatgccga ttgggctcaa attcatttca aaggaaagaa agcatatatt tcaactcact 929101 ttttaatgaa aaccgcaagc caagcgaaaa caacgaaaca gacagccttc tatacaccga 929161 cgcccgaaaa cggaaaagct aagcagctct catctggaac agaggtgaca atacttgggt 929221 ggggattcag tgaaaacggc ggatttgact tcacttgggc gttcgtggat tatggcggag 929281 ttaaaggcta tattcacaca aaggatttac aaatgcgata aaaaggcagg ccgaggcttg 929341 tctttttgcc tatgcatgaa acatttcttc tttctgcacg taacaatgag aaaggagatg 929401 atgatatgac gggtttagtc ggcggagggc ttatgatcat tgcgggcata ctgatcaaac 929461 tgtttcctcc caaatcgatc aacagtgtgt acggatacag aacgagacgc tcaatgtcag 929521 atcaaagatt atggaatgaa gcgaaccgtt acagtgcatc attaatgatc ctgtcaggct 929581 tggtgattgc gggaatgggt ttgctgctgg gatcaaactt gtttattctt cagcttatcc 929641 tgctgattgc cgcctgtgtc ataacattta tgctaacgga gaaaaggctg aaaatcatga 929701 cgcacagtca aggaggagat agaagtggac ggagttaaat gccagtttgt caatacgaac 929761 ggaatcacgc ttcacgttgc agccgcagga cgggaagatg gcccgttaat tgtcctgctc 929821 catggatttc ctgagttttg gtacggctgg aaaaatcaaa tcaaaccgct tgttgatgcg 929881 ggttaccggg tcattgctcc tgatcagcgg ggctacaatc tcagtgacaa accggaagga 929941 attgattcgt atcggattga tacattaaga gatgatatca tcgggcttat tacgcaattc 930001 actgatgaaa aagcaattgt catcggtcat gactggggag gagctgtcgc atggcatttg 930061 gcttccacac gcccggaata tcttgaaaaa ctgatcgcga tcaatatccc gcacccgcac 930121 gtcatgaaaa ccgtaacgcc gctttatccg ccgcaatggc tgaaaagctc gtatatcgca 930181 tacttccagc tgcccgatat accggaggca tcactaaggg aaaatgatta tgatacatta 930241 gacaaagcga ttggattatc cgaccgtccc gcgcttttta catccgagga tgtcagcagg 930301 tacaaagaag cgtggaagca gccgggcgcg ctgacagcta tgctgaactg gtacagagcc 930361 ctcagaaaag gaagcttggc agagaaaccc tcttacgaaa cagtacctta ccgaatgatc 930421 tggggaatgg aagaccgctt tttgagcaga aagcttgcga aagagacgga aaggcattgc 930481 ccgaatggac atctcatctt tgttgatgaa gcttcccatt ggattaacca cgaaaagcca 930541 gccatcgtca atcagctgat tttggaatat cttaagaacc aataagctaa aatttctctc 930601 catccgtctg tcataatggc agactttttc tgtgcgtttt ttttcatagt ctgttttaaa 930661 catgacaaaa taacattaaa aatcatgaat gtcaccataa aattgtaaca aaaaacaggt 930721 ttaaacgact ttaaaaaaag gaatagcctt actgaagatt tgtgtaaaac tcccctaagg 930781 caatacttaa aaagaataat aaaaagaagg tgccttaatg aagcaaggat taatctcgat 930841 tattatcccg tcttacaatg aagggtataa tgttaaactc attcatgaat ctttaaaaaa 930901 ggaatttaaa aacattcatt atgactatga aatattcttc ataaacgacg gaagtgttga 930961 tgacacgctt cagcagatca aagacttggc agcgacgtgc agccgggtaa aatatatatc 931021 tttttctcga aactttggaa aagaagccgc aattttggcg ggctttgagc atgttcaggg 931081 cgaggcggtt attgtcatgg atgccgatct gcagcatccg acatatttgc tgaaggaatt 931141 tatcaaaggc tacgaagaag ggtatgacca agtcattgcc caaaggaaca gaaaagggga 931201 cagctttgtc cgctcactct tatcatctat gtattacaag ttcattaata aagcggtgga 931261 agtcgatttg cgtgacggtg tcggtgactt cagattgtta agccgccaag ctgtgaatgc 931321 acttttgaag ctgagcgaag gaaaccgctt ctcaaaaggc cttttttgct ggattggctt 931381 tgatcagaaa attgtatttt atgaaaatgt cgaacgaaaa aacggcacct ccaaatggtc 931441 gttcagcagt ctgtttaact acggaatgga cggcgtcgtt tcatttaatc ataagccgct 931501 gagattatgt ttttatacag gcattttcat cctgctgctt tccatcattt atatcattgc 931561 cacattcgtt aaaattctga ctaacggtat ttctgtgcct gggtatttca ccattatctc 931621 agcagtgtta tttctcggcg gagtacagct gttaagtctt ggaataatag gtgaatatat 931681 cggccgaatc tattatgaaa caaaaaaacg cccgcattat ttgatcaaag aggcgaatat 931741 cccgaacaaa gacctgcctg aaacgaacga attaaaaagc atgcggcgtc tgacaaaaat 931801 gcactgaaaa taccaagcgc cattggcagt gctttttttg cgtgtctatt atcttaaaag 931861 caagactgga gaattcatat gaaaagaaaa catatcatga tctatgcggc cagtttgctg 931921 gtgtccgttc tggcacacgc tttttttgtg aaagaatggg cggaaggcag gtatatgaca 931981 ggtccgggtg acgggcttgc gcaaatgatc gtatttaaaa aattattatt tgaccaatat 932041 acacacggga attttttcta caattattca ttcggacttg gcggcggcac attcagtcag 932101 ctcggctatt atttttctgc gtcttttctt tttcttgctg tgtctgccgc tgtttggctg 932161 cttcaagccg tccagctgat cggagaaacg gatacgcttt tttgggcaga gtcagctgtt 932221 tttatcagta ttttcaaatt gagcttgatc atctttacgt ccgcttctgt ttttcattat 932281 cttcttaagc acagggcggc atcgttcacg ggagccgtgt tatacggcgt ctcaattatt 932341 tatttccgtc acgaagcgta ttgggaattt ttcaccgata caatggtttg gcttccgctg 932401 cttgtgcttg gcgcagaaaa aattattaga gagcggcgtc cggcgtggtt tatcgttgcg 932461 tgttcgctga cgttaatcaa caatttttac tttgcataca taaaccttat attcatcgga 932521 atctatgtgc tgttcagatg gctgatccgt ttggaaccac atgaagagaa aagatggatt 932581 caaatcagat tatttctcgt ttcaggcttc atttcttttg gcatcagtgc ggcggcgttt 932641 gtgccggtag tatacggttt tttaaacaac ctgcgccctc catacagcca gaaaatagag 932701 tggctcaatt tcgatgataa tatcttattt tcgagccgga tcatcattgt gccggccgct 932761 tttctgctgt ttttgtttat tatttctttt tacaaaaacc gtgtgtttcg tctctttgcc 932821 gggttgagcc tgctgtttat tctgtttcat ttcagtccgt atgcggcaag cgtctttaac 932881 ggtttttccg ccccgcaaaa ccggtttgaa tatgttctgg cctttaccat tgcgggagca 932941 gctgcggctg gtttgtcaca gctgtctgaa ttgaaacgga aagaactgct cccggccgca 933001 gctgtcgtcc tgcttcttta cttgtatcat atccaaaggt ataagctcga tatatggaag 933061 cctgcgaatg aaagtattct attgctctta ctcatgacaa tcgcagcctt gtttgctgca 933121 gcttttgcga aaaaacgggc aaaaatggct gtgtacggta taatcattct ttcttcgctg 933181 tttgtcgcca actcctatca aaaatacgcg ctctcagaag gcggcgattt ggacagtgtg 933241 acaaaagaat atcttacaag tgaggaatac agagggcggg aatcatctga gctcatcaga 933301 cgtttacaga aggaagacga tgacccgctc atgagaatcg actggatgaa cggggtccgc 933361 aataatacgc caatcattta cggatttaat ggcttcagcg cgtattccag cattttaaac 933421 aaagatctgc tggccttcta ttggaatgat ttaagcatcg atatgggcag ggaaagcgtc 933481 agccgttacg cgtcattggg agacagggcg aatttataca gcctgcttta cggcaaatat 933541 tatatgaccg aaaaaacaaa cgaagccagc gtcccgtacg gcttcaaaaa gcatttagaa 933601 acagagcatt atgcagttta tgagaatcag tacatgcttc cattcgttaa aacagcggat 933661 gccatataca gcgaaagtga gctggaccga ttgcccgctc ttgcgaaaga acaggcgatg 933721 ctgaaaggaa ttatattaaa agatccatca ggaaaaacgg agcagacacc aaaaccgtcc 933781 aatttgatca ccaagtcgga catcaccgca aaacaagccc agtatcaaaa cgggctgcta 933841 accgtaactg gagaaaacgg aggagagctg atcatcaccc cgaaacagcc atcatccgct 933901 ccgggagact actatgtcag cttttatttg aaaagcaaag caaaagacaa aggatttaca 933961 ttaaaggtaa atgattatgt cacaacaagg aaatcgaaca aatcgatcta taaaaccgga 934021 gtaaataata taacggtaag agtgcctaaa tcaggccata tctcaatcaa tcttccgaaa 934081 ggaacctatg agctgagaaa catagcgctc tatgaagaaa attaccaaac gctgaaaaac 934141 gctgtaatgc aaaataaaac agagaaagca gacaaactga attggaacaa aaatcgactg 934201 accttttcct atcatctgtc aaaagaccag tacatcatgc ttccgatccc atatgaaaaa 934261 ggctgggagc tgaagatcaa cggaaaaaca cagaagatcg aaaaagcgga ttatgctttt 934321 ataggcttca aggcgcaaaa gggagacaat cacattgagc tgacttacta tccgccatac 934381 ttcaaaatat cggcgatcat atctctcgtc agtctgctgc ttgctgtttt ttatataaga 934441 cgtaaaaagc ccggctctat atagagccga gctttaattt tttctgaagt ttttcttcgc 934501 tgaatatcca tcccgtatag gatgaacgaa tcgtgagatc atggccgata tgaacaattg 934561 cgacaaacgg ataatggcct ttgctccgat aacgcaggtc gataaatctc acctcataat 934621 gatctttaaa cgtatccact tcccaccggt ataccggaga aaaggacaga aacgccgcga 934681 tgttatcatc ctgctttgcc gcatgcatta catcggtttc aggaacaggc acccgattaa 934741 atgtatccag aatcacgaca tgtccttcca tgcttcttcc tacatagaaa gcatgtgctg 934801 tcgtcactgc gattcgccat tgcctgaatt tcatcgttgg agaaataata atgctttcga 934861 tctcatcatg aatcatctca tgaagcttcc gtttaattct cagctgcatg atcaggcgca 934921 ccaagtagta gcctaccaat atgatatata agctgagaaa cgtgatgccg ggactcccgc 934981 ctgcatacca aatcgcgata gctgccagat ggctgataaa aataaacgga tcaaacgtat 935041 taatcagccc gagcgcaacc cattttttcg aaaacggacg aatggcttgt gttccatagg 935101 cgttgaatat atcaacaaag acatgcagaa cgactgccag cagtgtccac agccacaggt 935161 gcagaaaatc ggcctgagga taaaataaat acagaatcgc cgggatgatg acagaccaaa 935221 acaaaacggc gggaattgaa tgggtaaatc ctctgtgatt ccttatataa acagcattgt 935281 ttttaagctt taacacagta tcaatatccg gagcctgaga gcccgcaagc gttgcgatca 935341 taacagcgtg agccattgcc ggatctgatc cgacaacagg atcaagcgtc gcaataccgc 935401 ccagtgcgat gcccataacg acatgtgtgc ccgtatccat aggtgacctc cttgcagggt 935461 gatcctgcac attcactttg taagaaattc cccattttca tatacccaat ttttaaactg 935521 attcaatcgt tctcatatgt ttccgctttt tctttattac tatttaatgt aacatattat 935581 cgtactgtgc ccttagtgta caacaaaaaa cagtctaaag aaaagcgggg cgcgaaagac 935641 tggggagaaa cacatatgaa cgtacttgaa gacaaattaa aacaaaaaga catacagcaa 935701 tttcgcgatg atttaatctc atggtttgaa cgagagcagc gcgttttgcc gtggagagag 935761 gaccaagatc catataaggt gtgggtatct gaagtgatgc tgcagcaaac gagagtagag 935821 acagtgattc cttactttct ccggtttgta gaacaattcc cgacagtgga agcgctcgct 935881 gatgctgatg aagaaaaggt gctgaaagca tgggaagggc tcggctatta ttcgcgagtc 935941 agaaacctgc aaagcgcggt aaaagaagtg aaacaggaat acggcggcat tgttcctcca 936001 gacgagaaag attttggcgg gttaaaaggc gtcggccctt atacaaaggg agcggtgctc 936061 agcattgcct acaataaacc cattcccgcg gttgacggaa atgtgatgcg tgtcatgtcc 936121 aggattctat ctatttggga tgatattgcc aaaccaaaaa caagaacgat ctttgaagac 936181 gccatacgag cttttatttc caaagaaaaa ccatctgaat ttaatcaggg cttgatggag 936241 cttggagcct tgatctgtac gccaaaatca ccctcatgcc tgctttgccc ggttcagcag 936301 cattgctcag catttgaaga aggcactgaa cgggagcttc cggtaaaaag caaaaagaaa 936361 aagcccggga tcaaaaccat ggccgcgatc gtactgactg atgaagacgg acaagtgtat 936421 atccacaaac ggccgtctaa aggtttgctc gccaacctgt gggaattccc gaatcttgaa 936481 acacaaaaag ggatcaaaac tgagcgtgaa cagctcattg ctttcttaga aaacgaatat 936541 ggcatacaag ctgatatcag tgatctgcaa ggtgtagtcg agcatgtttt cacccacctg 936601 gtatggaata tttcagtgtt tttcggtaaa gtaaaacaag tgtcggatac cagcaagctg 936661 aaaaaagtaa cgaaagaaga gctcgaacaa tttgcgttcc cggtgtcaca tcaaaaaatc 936721 tggaagatgg caggagaagc agccgccatc tcggctgctc cgtaaaccat tcttaatcgt 936781 aagagacgcg cgtgccgtgg ctgtagtccg cttcattgcg cttcattccg ccgcgcgctt 936841 caatttcttg cgttaattcc cggtattttg attggccttc ttcgttcaaa taaggcataa 936901 tttgctgaaa ggcatgatga aaataagcga gttcactgtt cttccaatct tttttggaaa 936961 ccatgttcaa ttcgctcata tcacgtccga catacataac agaagacccc ctttaaagtt 937021 cttgccatta ttgtttgtgg aaataaaaga actatacgct acaaggagat gaggaaaaat 937081 ggaacaaaat aaatgtgcac tcgtaacagg aagcagccgc ggtgtcggaa aagcggccgc 937141 gatcagactt gctgagaacg gctataacat cgtcattaac tatgcacgca gcaaaaaagc 937201 agcattagaa acagcggaag aaatcgaaaa gcttggcgtt aaagtgcttg tcgtaaaagc 937261 aaacgtagga cagcctgcaa aaatcaaaga aatgtttcag caaattgatg aaacgttcgg 937321 cagacttgat gtttttgtca ataatgccgc ttcaggagta ctaagacctg tcatggaatt 937381 agaagaaaca cactgggact ggacgatgaa cattaatgcg aaagcattgc ttttctgcgc 937441 tcaggaagct gccaagctaa tggagaagaa cggtggcggg catattgtca gcattagttc 937501 attaggctct atccgctatc ttgaaaacta caccacggtc ggtgtatcaa aagcagcgtt 937561 agaggcttta acccgttatc ttgccgttga gctttcacca aaacaaatta tcgtcaatgc 937621 tgtttcaggc ggagcgatcg acacagatgc gctgaagcac ttcccgaata gagaagatct 937681 gcttgaggat gcgcgccaaa atacgccggc gggacgcatg gtcgaaatta aagacatggt 937741 tgatactgtg gagtttctag tgtcttccaa ggctgacatg atccgcggac agacaattat 937801 cgttgacggc ggacgctcac tgctcgttta aaaattttta aaaaagagga atagctatac 937861 gatcacctgc acattctaat gaccgtggag gtgataacaa tggctaactc aaataacttc 937921 agcaaaacaa acgctcaaca agttagaaaa caaaaccaac aatcagctgc tggtcaaggt 937981 caatttggca ctgaatttgc tagcgaaaca aacgctcagc aagtcagaaa acaaaaccag 938041 caatcagctg gacaacaagg tcaattcggc actgaattcg ctagtgaaac tgacgcacag 938101 caggtaagac agcaaaacca atctgctgaa caaaacaaac aacaaaacag ctaatcactg 938161 aaacagaaaa aagcacttca tcttcgggtg gaagtgcttt tttctgtttg aaaaacgaca 938221 aaacttgtgg aaggtctaca gaatgagtca aagggtttgc tttatggaga tcgaaatgat 938281 taaaggagga aatgtttata ctttcatcag gctgaaggag gaaccgatga ccgaatttga 938341 aaagctggta agtgaacaga tgaaaacgat ggataagctt ctcgatctcc aatcagagct 938401 cgaccgctgc aaacaaattg aggcggaact ccggcatttg gaaagggatg caaggctgcg 938461 tgggattcag gctgaaattg cggtaaaacg gaaacacctt gccgatatac aggatatgtt 938521 tcaaaagcag acagagcagg tcattcgttc atatcgcagc tcagaaaagc cgtcttcctt 938581 tgtgtagtgc aggaatgtgc cattccccgg ccggaatggc tcttttattt tcatttttca 938641 atttgtaacg ttataatagg taaaagacgt tgtcggtaag caaatttgga catactaact 938701 gtagggcttt atagaaagta ggggagaaat atgggctatc ccaaggaagg agaaaccatt 938761 caaattcaca gctataagca caacgggctg attcatagaa tttggaatga gacaacaatc 938821 ttaaaaagta cagaaatgtg tgtcatcgga gccaatgacc ggacgatggt aaccgaatca 938881 gacggccgga catggataac cagagagccc gcaatctgtt attttcacgc aagacaatgg 938941 tttaatgtca tcgggatgct gagggaagac ggggttcatt attattgcaa catcagttct 939001 ccgtttgcct atgatggcga agcaattaaa tatattgatt atgacttaga tgttaaggtt 939061 tttcctgaca tgacctacaa tattctcgat gaagacgaat atgatgatca tcggaaagcc 939121 atgaattatc caaaagaaat cgacagtatt ttaagagact acttaaatac gctgctccat 939181 tggattcacc agcgtcaggg accgtttgcg cccgagtttg tcgatatgtg gtatgaacgg 939241 tatttgcgct atacaaaata atggttacgt aaaaacctgt tgcggggtac aacaggtttt 939301 tcacatgggc tcacacacat catgataaag agagaggggg aatcaaccgt gggggttatg 939361 aaacgctaca tgcaattcgt caaaccttat aagaagcaaa ttttcgttac agtgttaatc 939421 gggatcgtaa aattctccat tccgcttgct ctcccattgc ttctgaagta cgtagttgac 939481 gacattattc aaggaggcgg cacggccagt gacaaaacca cgtcattgtt cacgattatg 939541 gcgatcatgt tcgccttatt tttaattttg cgcccgcctg ttgaatatta ccggcaatat 939601 tttgcccagt ggactgccag caaggtgctt tatgatataa gagctaagct gtttgaccat 939661 atacaaaaac tgagccttcg tttttacgcg aatacaagaa caggggaagt catttcccga 939721 gtgattaatg atgtagaaca aacaaaggat ttcgtcatca cagggctgat gaatatatgg 939781 ctcgatatgc tgacgatttt gattgtaatc tctatcatgc tcacactgga cgttaaatta 939841 acgctgatct ctatcgtttt attcccatta tacggaatat cagtgaagta tttttacggc 939901 cgtttacgaa agctgacaag ggagcgctca caggctcttg ctcaagtgca ggggcatttg 939961 catgaacgca ttcaaggcat gcctgtcatc agaagctttg cgatagaaga tcatgaacag 940021 gctcaattta atgagaaaaa cggtcatttc ttagataaag ccatccgcca cacgaattgg 940081 aacgcgaaaa cctttgcggt cgttaatacc attacagatt tggcgccgct catcgtcata 940141 gcgtgcgccg ggtattttgt cattaatgga ccgctgacag tcggaacaat ggtcgcgttt 940201 gtcggatata ttgacagaat gtacaaccct gttagaaggc tgatcaattc ctctacaact 940261 ttgacacagt caatcgcatc aatggacagg gtgtttgaat ttattgacga gccctatgaa 940321 ctcactgaca aaccaaatgc gataaaggcc gatcagattc gcggaggagt ggagtttcaa 940381 aacgtttcgt ttcaatatga gaaggacaaa gaaaatattc ttcatgatgt atccttaaaa 940441 gtaaatagag gagaaactgt agctctcgtc ggcatgagcg gaggaggaaa atcaacgctc 940501 gtcagcctga tcccaagatt ttatgatgta acaagcggca gactgctgat tgatgggacg 940561 gatattcgcg attatgaagc aagaagcctt cgcaaccagg ttggtatggt gcttcaagat 940621 acctttttat ttagtgaaac gattcgggaa aatatcgcga tcggcaagcc tgatgccaca 940681 cttgaagaga taatcgaagc cgccaaagct gcaaatgccc atgaatttat catgagtttt 940741 ccagaaggat atgagacccg ggtgggggaa cgaggcgtta agctttcagg cggacaaaag 940801 cagcggatct caattgcgcg ggtattcctg aaaaatccgc cgctcctcat tttagatgaa 940861 gctacatcag ctctggattt ggaaagtgag cattacattc aagaagcgat ggacaaactg 940921 gcgaaggata gaacaacttt tgttgtcgcc caccgtttat cgacaatcac ccatgcggat 940981 aagattgttg tcatggaaaa cgggacaatc attgaaatcg gaacccatga tgaactcatg 941041 gactatgaga gccaatacaa gcacttattt accattcaaa atttgaacta aaacatcaat 941101 cttatatcct tttaacgaag gatataagat ttttttgtat ataaaaaaac ccggctgttt 941161 aaccgggtta ctcttctgtt tctatttcgc agtctttcgg atgatacgtt tgaaaacttg 941221 tgataagtgt ttctaaatgt tcaagctgct cgcgatattc cacggcgctt gccataatat 941281 tgagcatgtt gtaatcaata agctcctcat ccgtattctg ctgatttttt aaaaatgact 941341 ttgttaaaag ctgcttatac cggatgcctt cttcaaccgc gtcatcatgc ggcttgattt 941401 ttccgacaaa cctcatcaaa atccgctcgt gccagtaaag caggtaatca agttcttcag 941461 tcaatgtttc ctgaaactct tccggcatat gatagatctc gttttccaga cgatgcagct 941521 tcttcaatgt atcaagcgcc cgatttgcag taataatggc ctgtctgaac aggacaagct 941581 ttcttgattt cacataagtc gttttcttaa agtaacttct ttcttcttta tatagaagat 941641 atgtctgatc aagcttgatc attttttctt tcagtttttc aatatcctct ttcaaaatcg 941701 aatgctctgt cgactgccgc atggacaatc tgatccactt cataatttct tcggtgtttt 941761 cgacggtatt atgaatcagc tttgtttcgt acttaggagg caaaaacaca aggttgacga 941821 taaaggaaga aagcacccct aagatgactg tgcttgttct gatcagcgcg aacattaaaa 941881 agtcgtcacc ggcagattct aatatcgcaa tgactgttac aagagcaatt gaaattgtat 941941 gttcaatttt aagtttcagc atgattgtaa tgacaataac tgctgttaac ccgatcataa 942001 tcgggctggg tccgaaaata aggccgaaca ctgtggcaat cacagctccg atgatatttg 942061 cttgaacctg gtcaataata atgagaaaag agcggtaaat cgacggctgg atcgcaaata 942121 tcgctgcaat tccagcgaaa atcggcgcgg gaagcccgat ccacgaagcc aaataaaggg 942181 caagtgtaat cgcaatcccg gttttgaaaa tgcgggcacc aagtttcatt ggtttgtgcg 942241 tgcattcctt tctatagtaa attgtgtgac atagcaaatg ggctaatcct taaaattccc 942301 ggttagttta tttgctaaac aattaagtaa tatacaggga tcgatacaaa tattcaagct 942361 atttttctag aaaaagacca aaatcttaca cgctgtttga ttccataaaa aaacaggagc 942421 tcaaagctcc tgttcaaggt atttgattct agttttttag atgtttaaat gcatcctcga 942481 ccgctgtaag cgtgtcttta atatcctgct ctgtatgtgc tgtggtaata aaccaagctt 942541 catacttaga aggtgctaaa ttaattccgc gttccagcat cagcttgaaa aacgtagaga 942601 atgtttctcc gtcactccgt tcagcctgct cgtaattttc cactttctca tcagagaagt 942661 ataccgtgag cgcacctttt aaccggttga ccgtaatggt gatgccgtgt gtttctgcgt 942721 gcttcaaaat gccttcctca agcatagcgc caaggtgatc aagcttttca tacacgcctt 942781 tttctttgag cacttccaga caagcgatgc ctgataggat ggaagcgggg ttccctgcca 942841 ttgttcctgc ctgataagca ggccctagcg gagctacctg ctccatgatt tcttgtttgc 942901 cgccataggc cccaatcgga agtccgccgc cgataatttt cccgagtgct gttaaatctg 942961 gtttcacctg taagagatcc tgcgcgccgc catacataaa gcggaaagcc gtaatgactt 943021 catcgtaaat aacgagagcc cctgcattat gtgttaattc atttacttgt tctaagaagc 943081 cctctttcgg ctccacgata ccgaagttgc cgacaatcgg ttcaacgaga accgccgcga 943141 tttcactgcc ccatttttca agagctgctt tatagctatc gatatcatta aatggtactg 943201 tgatcacttc gtttgcaatg cttttcggta caccggctga gtctggtgtg ccgagagtag 943261 acgggccgga gcctgcggcg acaagcacaa ggtccgaatg cccgtgatag cagcccgcaa 943321 atttaatgat ttttgtccgg cctgtatatg cgcgagccac gcggatggtc gtcataacgg 943381 cttctgtacc cgaattgacg aatcttactt tgtccatagc gggaatggct tctttgagca 943441 tttttgcaaa tgtaacctcg tgtttcgttg gtgttccata caatacaccg ttctctgctg 943501 cttttttaat cgcttctgta atatgcggat gggcatgtcc tgtaataatc ggaccgtacg 943561 ccgctaaata atcgatgtat ttgttgccgt ccacatccca aaaataagcg ccgcttgctt 943621 tctccattgc aacaggagaa ccgccgccga ctgctttata tgatctagac gggctgttta 943681 caccgccgac aatgtgctgt aatgcctcat tgtgaagttc aattgatttt gtatgcaaga 943741 ataaaaacct cctatatctc catgcgtcct ttctattgta gcatgcttcc gaacaagaac 943801 aatggcttcg ggcttcagat tcagctgaga tggttgtaat ctggacaaga attggatacg 943861 cttaataaaa aaacatccgg aggtaacgta atgactatag aaatcggaca aaaagcgcct 943921 gatcttgagt taaaaggtga tcatggggaa acagtaaaat tatcggatta taaaggaaag 943981 tacatcgtgc tttattttta tccaaaggac atgacaccgg gatgtacaac tgaagcatgc 944041 gattttcggg acagtcacga aagcttcgcc gaactggatg ccgtcattat cggcgtcagc 944101 ccggacagcc aggaaaaaca cggaaaattt aaagagaagc ataaccttcc atttctgctt 944161 cttgttgatg acgagcataa gctggcggaa gcatttgatg tgtggaagct gaagaaaaac 944221 ttcggaaaag agtatatggg aatcgagcgt tccacttttt taattgataa agaaggccgg 944281 ctcattaaag aatggagaaa agtaaaagta aaggaccatg tagccgaagc gcttcaaacc 944341 ctcaaagata tgtctgaaaa gtaaatctct atgagcctat gcttactttt accctgatat 944401 caattgacaa attatcgtag aaagagttac actaattata aacattacaa tgtaagaatt 944461 ttttttagaa gagaggtgca tgacggatgg ctgcacatga actaaaagaa gccttagaaa 944521 cgttgaagga aaccggagtt cgcattactc ctcaacgtca tgcgattctg gaatatctcg 944581 ttaactctat ggctcatcca acagcggacg atatatataa agctctggaa gggaaatttc 944641 ctaacatgag cgtagcgacg gtatataaca atttgcgtgt gttccgggaa tcaggtttgg 944701 taaaagagct cacatacggt gatgcttcca gcagattcga ttttgtcaca tccgatcact 944761 atcacgcgat ttgcgaaaac tgcggtaaaa ttgtggactt ccactacccg ggccttgatg 944821 aagtggagca gctcgctgcc cacgtcacgg gcttcaaggt aagccaccac cgtttagaaa 944881 tttacggcgt ctgccaagag tgttcgaaaa aagaaaatca ttaaaaataa gctgaccgca 944941 cgaaacggtc agcttatttt atttcgacat tttcttttta ttataagact catcaaattc 945001 ttttccttct aatcccttat ctaaagtcag cggctctcgg caatgcatgc acatatcgac 945061 tactcctaaa acctttgtct ctttatcaca gcctggacaa atgacgcgaa ccgctttagt 945121 cgaaagcatt ccgatccaaa agtaaactac cgtgctgaga ccgatggata aaagcccaag 945181 tatcataaac aaactagaaa gcaaaactga ctctttgaaa aagatcccga tgtacataat 945241 gataaaccca acgaaaacca aacttaacgc aaatgttctg attttattaa ttttgctgga 945301 gtatttcgcc atgtccatcc ccctctgttt taactatagc acaaacccga tgggattttc 945361 ttcatgtttt cggttgaact ggaatttaca tatggagagt tactgtgaaa ttgtttataa 945421 tagttcaatg tgtttagaaa aaaggaattt cgttttaacc atagaattga atcaaataga 945481 gaataaaaaa atttgaacaa ttgcattgga ggaatagtga tggaaaatct tctccgtcca 945541 atttaccaag aaagagcaag tcaccccaat acattggctg tcattatgat tgagagaaga 945601 aacaaaacat cttccttaac agataacttt gatgcagctt tgctggtgat tgtaaaggat 945661 gctgatgagc cagtttttat aaagcattat gaatttgatc atcaaacagc ttctttgcat 945721 gtggtaacag attctcagat tcaagaatgg attttgcttg gaacaaatag aagaatcata 945781 gattggattg taaatggcag agtcttgttt gaccgtaatg aatacgtagt tgaactgatt 945841 gacaggctga atacatttcc gtttgccgaa cgtaaactga agatcggact cgaatacggc 945901 aaattaatca gaaggtatgt tgaagggaaa gctttttttg aagccaatca atttttagat 945961 gcctacaatg ccgttgttca tgcgctgcat catttagcac gtattgaagt aatcgacaga 946021 ggattccatc ccgaaaccac ggtgtggagc caagtgcgcc agatggagcc ccaagtgtac 946081 aaattatatt ccgagctgat tgaaagtcat gagagcctgg aaaaaagact tgaattatta 946141 ttcttagcaa atgattttct catccattcc aaagccgaga tcggttcggc gcatcttttc 946201 gaagtaatga aagaaaaaga catttggcaa ttcggtgagc ttcttcaaca tcatgaccta 946261 aagcacttta cccaagatct tggcgttatg cttgattact tgacggaaaa gggacttatc 946321 aacgtctgcc agatagaaac gaaaggacag gctgtctatc accgaggata ttcttttaaa 946381 aaaggtgttg actctgattc ttgaccgtgt tatattatta aacgtcgctg atgcgcttct 946441 gagaaaacaa gctcacagcg gcgggaaaat aaatcaaaaa aacatttgac aaaagaaagt 946501 caaaatgtta tattaataaa gtcgcttcaa caagaagtga aaatgatctt tgaaaactaa 946561 acaagacaaa acgtacctgt taattcagtt tttaaaaaat cgcacagcga tgtgcgtagt 946621 cagtcaaact agggcctgca cgacgcaggt cacacaggtg tcgccgcagg atgcggtgaa 946681 cttaacctgt gatccattta tcggagagtt tgatcctggc tcaggacgaa cgctggcggc 946741 gtgcctaata catgcaagtc gagcggacag atgggagctt gctccctgat gttagcggcg 946801 gacgggtgag taacacgtgg gtaacctgcc tgtaagactg ggataactcc gggaaaccgg 946861 ggctaatacc ggatggttgt ttgaaccgca tggttcaaac ataaaaggtg gcttcggcta 946921 ccacttacag atggacccgc ggcgcattag ctagttggtg aggtaacggc tcaccaaggc 946981 aacgatgcgt agccgacctg agagggtgat cggccacact gggactgaga cacggcccag 947041 actcctacgg gaggcagcag tagggaatct tccgcaatgg acgaaagtct gacggagcaa 947101 cgccgcgtga gtgatgaagg ttttcggatc gtaaagctct gttgttaggg aagaacaagt 947161 accgttcgaa tagggcggta ccttgacggt acctaaccag aaagccacgg ctaactacgt 947221 gccagcagcc gcggtaatac gtaggtggca agcgttgtcc ggaattattg ggcgtaaagg 947281 gctcgcaggc ggtttcttaa gtctgatgtg aaagcccccg gctcaaccgg ggagggtcat 947341 tggaaactgg ggaacttgag tgcagaagag gagagtggaa ttccacgtgt agcggtgaaa 947401 tgcgtagaga tgtggaggaa caccagtggc gaaggcgact ctctggtctg taactgacgc 947461 tgaggagcga aagcgtgggg agcgaacagg attagatacc ctggtagtcc acgccgtaaa 947521 cgatgagtgc taagtgttag ggggtttccg ccccttagtg ctgcagctaa cgcattaagc 947581 actccgcctg gggagtacgg tcgcaagact gaaactcaaa ggaattgacg ggggcccgca 947641 caagcggtgg agcatgtggt ttaattcgaa gcaacgcgaa gaaccttacc aggtcttgac 947701 atcctctgac aatcctagag ataggacgtc cccttcgggg gcagagtgac aggtggtgca 947761 tggttgtcgt cagctcgtgt cgtgagatgt tgggttaagt cccgcaacga gcgcaaccct 947821 tgatcttagt tgccagcatt cagttgggca ctctaaggtg actgccggtg acaaaccgga 947881 ggaaggtggg gatgacgtca aatcatcatg ccccttatga cctgggctac acacgtgcta 947941 caatggacag aacaaagggc agcgaaaccg cgaggttaag ccaatcccac aaatctgttc 948001 tcagttcgga tcgcagtctg caactcgact gcgtgaagct ggaatcgcta gtaatcgcgg 948061 atcagcatgc cgcggtgaat acgttcccgg gccttgtaca caccgcccgt cacaccacga 948121 gagtttgtaa cacccgaagt cggtgaggta accttttagg agccagccgc cgaaggtggg 948181 acagatgatt ggggtgaagt cgtaacaagg tagccgtatc ggaaggtgcg gctggatcac 948241 ctcctttcta aggatattat acggaatata agaccttggg tcttataaac agaacgttcc 948301 ctgtcttgtt tagttttgaa ggatcattcc ttcgaaacgt gttctttgaa aactagataa 948361 cagtagacat cacattcaat tagtaataca agatatcaca tagtgattct ttttaacggt 948421 taagttagaa agggcgcacg gtggatgcct tggcactagg agccgatgaa ggacgggacg 948481 aacaccgata tgcttcgggg agctgtaagc aagctttgat ccggagattt ccgaatgggg 948541 aaacccacca ctcgtaatgg agtggtatcc atatctgaat tcataggata tgagaaggca 948601 gacccgggga actgaaacat ctaagtaccc ggaggaagag aaagcaaatg cgattccctg 948661 agtagcggcg agcgaaacgg gattagccca aaccaagagg cttgcctctt ggggttgtag 948721 gacactctgt acggagttac aaaagaacga ggtagatgaa gaggtctgga aaggcccgcc 948781 ataggaggta acagccctgt agtcaaaact tcgttctctc ctgagtggat cctgagtacg 948841 gcggaacacg tgaaattccg tcggaatccg ggaggaccat ctcccaaggc taaatactcc 948901 ctagtgaccg atagtgaacc agtaccgtga gggaaaggtg aaaagcaccc cggaagggga 948961 gtgaaagaga tcctgaaacc gtgtgcctac aagtagtcag agcccgttaa cgggtgatgg 949021 cgtgcctttt gtagaatgaa ccggcgagtt acgatcccgt gcaaggttaa gcagaagatg 949081 cggagccgca gcgaaagcga gtctgaatag ggcgcatgag tacgtggtcg tagacccgaa 949141 accaggtgat ctacccatgt ccagggtgaa gttcaggtaa cactgaatgg aggcccgaac 949201 ccacgcacgt tgaaaagtgc ggggatgagg tgtgggtagg ggtgaaatgc caatcgaacc 949261 tggagatagc tggttctctc cgaaatagct ttagggctag cctcaaggta agagtcttgg 949321 aggtagagca ctgattggac taggggcccc taccgggtta ccgaattcag tcaaactccg 949381 aatgccaatg acttatcctt gggagtcaga ctgcgagtga taagatccgt agtcgaaagg 949441 gaaacagccc agaccgccag ctaaggtccc aaagtatacg ttaagtggaa aaggatgtgg 949501 agttgcttag acaaccagga tgttggctta gaagcagcca ccatttaaag agtgcgtaat 949561 agctcactgg tcgagtgact ctgcgccgaa aatgtaccgg ggctaaacgt atcaccgaag 949621 ctgcggactg ttcttcgaac agtggtagga gagcgttcta agggctgtga agccagaccg 949681 gaaggactgg tggagcgctt agaagtgaga atgccggtat gagtagcgaa agaggggtga 949741 gaatcccctc caccgaatgc ctaaggtttc ctgaggaagg ctcgtccgct cagggttagt 949801 cgggacctaa gccgaggccg aaaggcgtag gcgatggaca acaggttgat attcctgtac 949861 cacctcctca ccatttgagc aatgggggga cgcaggagga tagggtaagc gcggtattgg 949921 atatccgcgt ccaagcagtt aggctgggaa ataggcaaat ccgtttccca taaggctgag 949981 ctgtgatggc gagcgaaata tagtagcgaa gttcctgatt ccacactgcc aagaaaagcc 950041 tctagcgagg tgagaggtgc ccgtaccgca aaccgacaca ggtaggcgag gagagaatcc 950101 taaggtgatc gagagaactc tcgttaagga actcggcaaa atgaccccgt aacttcggga 950161 gaaggggtgc tctgttaggg tgcaagcccg agagagccgc agtgaatagg cccaggcgac 950221 tgtttagcaa aaacacaggt ctctgcgaag ccgtaaggcg aagtataggg gctgacgcct 950281 gcccggtgct ggaaggttaa gaggagcgct tagcgtaagc gaaggtgcga attgaagccc 950341 cagtaaacgg cggccgtaac tataacggtc ctaaggtagc gaaattcctt gtcgggtaag 950401 ttccgacccg cacgaaaggc gcaacgatct gggcactgtc tcaacgagag actcggtgaa 950461 attatagtac ctgtgaagat gcaggttacc cgcgacagga cggaaagacc ccgtggagct 950521 ttactgcagc ctgatattga atgttggtac agcttgtaca ggataggtag gagccttgga 950581 aaccggagcg ccagcttcgg tggaggcatc ggtgggatac taccctggct gtattgacct 950641 tctaacccgc cgcccttatc gggcggggag acagtgtcag gtgggcagtt tgactggggc 950701 ggtcgcctcc taaaaggtaa cggaggcgcc caaaggttcc ctcagaatgg ttggaaatca 950761 ttcgcagagt gtaaaggcac aagggagctt gactgcgaga cctacaagtc gagcagggac 950821 gaaagtcggg cttagtgatc cggtggttcc gcatggaagg gccatcgctc aacggataaa 950881 agctaccccg gggataacag gcttatctcc cccaagagtc cacatcgacg gggaggtttg 950941 gcacctcgat gtcggctcat cgcatcctgg ggctgtagtc ggtcccaagg gttgggctgt 951001 tcgcccatta aagcggtacg cgagctgggt tcagaacgtc gtgagacagt tcggtcccta 951061 tccgtcgcgg gcgcaggaaa tttgagagga gctgtcctta gtacgagagg accgggatgg 951121 acgcaccgct ggtgtaccag ttgttctgcc aagggcatcg ctgggtagct atgtgcggac 951181 gggataagtg ctgaaagcat ctaagcatga agcccccctc aagatgagat ttcccattcc 951241 gcaaggaagt aagatccctg aaagatgatc aggttgatag gtctgaggtg gaagtgtggc 951301 gacacatgga gctgacagat actaatcgat cgagggctta accatatttt tgaatgatgt 951361 cacacctgtt atctagtttt gagagaataa gtttttcaaa aaaacacttg attttctcaa 951421 gaatacatag tataatgtta aatgtcactg aaattgtctg gtgatgatgg cgaagaggtc 951481 acacccgttc ccatgccgaa cacggaagtt aagctcttca gcgccgatgg tagtcggggg 951541 tttccccctg tgagagtagg acatcgccag gcagacttca ttccgcagta gctcagtggt 951601 agagctatcg gctgttaacc gatcggtcgt aggttcgaat cctacctgcg gagccattat 951661 tggagagctg tccgagtggt cgaaggagca cgattggaaa tcgtgtaggc ggtcaactcc 951721 gtctcaaggg ttcgaatccc ttgctctccg ccactgatac ttatacataa ttacaattga 951781 aagtctgggc ccgttggtca agcggttaag acaccgccct ttcacggcgg taacacgggt 951841 tcgaatcccg tacgggtcat tatatgatgg aggattagct cagctgggag agcatctgcc 951901 ttacaagcag agggtcggcg gttcgagccc gtcatcctcc accattatat catcgcgggg 951961 tggagcagtt cggtagctcg tcgggctcat aacccgaagg tcgcaggttc aaatcctgcc 952021 cccgcaacca aattttaaaa tggtccggta gttcagttgg ttagaatgcc tgcctgtcac 952081 gcaggaggtc gcgggttcga gtcccgtccg gaccgccatt tgaatactta ggctcggtag 952141 ctcagttggt agagcaacgg actgaaaatc cgtgtgtcgg cggttcgatt ccgtcccgag 952201 ccaccaccta tgccggtgta gctcaattgg tagagcaact gacttgtaat cagtaggttg 952261 ggggttcaag tcctcttgcc ggcactgttt tttcaaaatt taatgtggag gggtagcgaa 952321 gtggctaaac gcggcggact gtaaatccgc tccctcaggg ttcggcagtt cgaatctgcc 952381 cccctccacc atttataggg gcatagttta acggtagaac agaggtctcc aaaacctccg 952441 gtgtgggttc gattcctact gcccctgcca aatttatgac atcttgagat tatggcggtt 952501 gtggcgaagt ggttaacgca ccagattgtg gctctggcac tcgtgggttc gattcccatc 952561 aatcgcccca tattatcatt gggctatagc caagcggtaa ggcaacggac tttgactccg 952621 tcatgcgttg gttcgaatcc agctagccca gtctcacttt ttatatcaac tgcatataat 952681 gtattaagtc cattaaaaat gcggaagtag ttcagtggta gaacaccacc ttgccaaggt 952741 gggggtcgcg ggttcgaatc ccgtcttccg ctccaattac ggcggcatag ccaagtggta 952801 aggcagaggt ctgcaaaacc tttatccccg gttcgaatcc gggtgtcgcc ttcttattgc 952861 cggggtggtg gaattggcag acacacagga cttaaaatcc tgcggtaggt gactaccgtg 952921 ccggttcaag tccggccctc ggcaccaatt ttacttacat ggtaagttga attggtgttt 952981 gtgttttatc attataacta atcatattaa tgatctacat aagtagatca tttttttaat 953041 gctttgattt atcataacaa gttaagttcc gaggcctatt ataaagcggc tgtatagcta 953101 gtctttcaac acttttattt tatatttcca taaaaacttt tttgaaatac gttgacactt 953161 tatgagatcc atgatatatt tatattcgtc ggttagatac gacgtaaaac ttgccggtgt 953221 ggcggaattg gcagacgcgc acgactcaaa atcgtgttcc ttctggagtg tcggttcgac 953281 cccgaccacc ggtatactga aaaacccgtt tcttaacaga aacgggtttt tattttttat 953341 taaagaaaag gagcctcggc tcctttttat acttactcag cgtattggtc taggatctct 953401 tctagcacct cttctagctc ttctgtatct tcaagctctg attggctgaa acggacgcgt 953461 acaagctgtt ctccgtcatt atacatctct tccaaccacc ctcggagtcc tcttgctctg 953521 cggtcgactt cgaaaatgat ttccaaaccg tcttcgtcta aaaggaaaat gagctctaat 953581 tcatcaagca tctgacgata atatccggaa gtcggaacga attcgaattc ttgaacgaac 953641 ggaagacgac gctggaagta gggcgcttgt tcgcagtctg cttcgttaag acggaagccc 953701 aggttttcga ttgcttcaag cacattttca atccaagggt gcgcttcaac gaaaatgcgg 953761 tcatgatcgg atttatcgat accgccttga atgtcaaggt ctgtcaccac ggcaacctct 953821 actttcccta cagtgatcgg cgtatctaga ggcagagtga atgtgaacgg aaattgatgc 953881 tcttcaccag gctgtatggt aaatgaacca gtgacccgga aagaatgaat tgtagcgtat 953941 ttccggtgct cttcatcgtc ttttacaatg acataccgtg tgctaagctg taaatcgata 954001 taacggatgt cctgagcgat ttttccgcct ttgacatgta ccgttccctg tacttcttct 954061 cctggaaaat atgcgtcttt ttctaaaatt gtatctactt ttgcagctcc aattccggca 954121 cttgccgcaa gcttcttaaa aaatgacatg ttagatcttc ccctttttct tttttctcaa 954181 cagatatacg taagaaggag gaaaaaagat tcgtttgatt catacttttt tcctattatt 954241 cgtctcggcc tagggacaga ctaagaataa tattgaaaat aaaggagtcg atggaagtga 954301 ataaagaaag tttggttgca gatgaattac acagaatgtt tttggctggt gagctgcaaa 954361 tcacagtaga ggaggatata aacaatattt ccgaaaggct gagaaacggc gatctcagtt 954421 tagaccgatt aagcggtgaa gacgtgttta taaaagaaac ggtaaatgag gctttaagaa 954481 gagtggagca ataaaaaaga gacggcatct catctttgag atcccgtctc tttttgtggt 954541 ctttgctgta agataaaagc gaatcgattt ggaattgctc acccgagcca ccccttttct 954601 aacagaagat ctgacagttc atcatggaga taaacagctg tatctaattg atcatgcaat 954661 gctcttctga tgtggggatt ttcggttgct gttgttgcga cagtgtattt gttaatgctg 954721 gtttttattg ttgttaacaa atcaagaata tctttgggac aaagactttg ttcaatggga 954781 aaccacctcc tttgtttttt tagcagctcc tgataagaaa gtatttgact ttgtttcttg 954841 cttctataca aaatgctata ataagcaaca aattttgttg gggggtgtga tgatgaagca 954901 gattattgcg atggggggcg ggggtttttc gatggagccg gataatttgt ccctcgatca 954961 atatatcctc aatcaatcaa aacgagagca gcctcgtatt tgttttttgc cgacggcgag 955021 cggagattcc caaaactata ttcagcggtt ttatcatgca tttcaaacat tggattgcgt 955081 gccgtctcat ttatctttgt ttaagccacc atcatcagat ttagtttctt ttgttatgga 955141 aatggacgtg atttatgttg gcgggggaaa tacgcggaat ttacttgtgt tatggaaaga 955201 gtgggggctg gaccatattc tcagggaagc atggaagaac ggtgtggttg tagctggaat 955261 aagtgccggt gcgatctgct ggtttgaaga aggggtgaca gattcagccg gaccgctgac 955321 aagtttgaaa agtttaggtt ttttgcaagg gagcttttgt ccccattatg acggggaaaa 955381 ggatcggaga ccggcatacc accagctgat atctaacaag ttcttatgca gtggctatgc 955441 agcggatgat ggggctgctc tccatttcat aaatgatcag ctgtttcaga ctgtgagttc 955501 aaggtcgggt gcaaaggcat atcgggtgat gatggctgaa catgaaatag ctgaaatccc 955561 gttgccggtc aaatatttag ggtgaaattg gctgaatatt atctatattc ctcttttttt 955621 cagattgatt ttatgataag atgagtgcga aatcaatagt tactgggggt gcccgctttc 955681 gggctgagag agaaggcaag cttcttaacc ctttggacct gatctggttc gtaccagcgt 955741 ggggaagtag aggaattgtt tttgttattg tcttgctggg caataatatg tttctttctg 955801 actgtaaccg ggttcattta tatgaatccg gttttttgtg ctggttatgg gcttgatttt 955861 gtcctttcaa acgtagaaag gggaaggaaa agtaatgcaa aacaattcag tgcagcaagc 955921 caacatttcc attatgtcaa gtttttcagg cagcaagaag gtatacgtgg agggttcttc 955981 ttcggacatc caagtgccga tgagggagat tgcattgagt ccgacgacgg gatcgttcgg 956041 cgaagaggaa aacgcgcctg tgcgtgtcta tgatacaagc ggaccgtata cggaccctga 956101 agtaaccatt aatattcaag aaggattaaa gccgctccgc caaaaatgga tcacagagcg 956161 cggtgacgtg gaagagtatg aaggtcgggc tataaaacca gaagataacg gttataaaaa 956221 agcaaaacca aacgtaagct atccaggatt aaagcggaaa ccgctgaggg cgaaggcagg 956281 tcaaaatgtc acacaaatgc actatgcaaa aaaggggatc attacacctg agatggaatt 956341 tatcgccatt cgtgagcatg tgtctcctga attcgtcaga gacgaggtag ccagcggccg 956401 ggcgattatt ccttcaaaca ttaatcaccc tgaaagtgag ccaatgatta tcggccggaa 956461 ttttcatgtg aagattaatg caaatatcgg gaattcagcg gttacgtcat ccattgaaga 956521 agaagtggaa aaaatgacgt gggccatccg ctggggagcg gatacgatga tggatctctc 956581 taccggaaaa gatattcata cgacgcgtga atggattatc cgcaattgcc ccgtgcctgt 956641 gggaactgtt ccgatttatc aggcgcttga aaaagtaaac ggcgtagctg aggatttaac 956701 gtgggagatt tatcgtgata cgctaatcga gcaggcagag cagggagtgg attattttac 956761 gattcacgcg ggtgttttgc ttaggtatgt accgctgact gccaaacgga caactggtat 956821 cgtgtcacgc gggggagcga ttatggcgca gtggtgtctg gctcatcatc aagaaagctt 956881 tttatacaca cattttgaag aaatatgtga gattatgaaa atgtatgata ttgctttctc 956941 tcttggggat ggtttgcgtc ccggatcaat tgctgatgcc aatgacgaag cgcagtttgc 957001 tgaattagag acgcttggag agctgacgca aattgcctgg aagcatgatg ttcaggtgat 957061 gattgagggt cctggacatg ttccgatgca taaaatcaaa gagaacgtcg ataaacaaat 957121 ggacatttgt aaagaagcgc ctttttacac attggggccg ttgacaacgg atattgctcc 957181 gggatatgac catattactt cagcgatcgg agcggcgatg atcggttggt acgggacagc 957241 aatgctttgt tatgtaacgc cgaaggagca tttggggctg ccaaaccgtg atgatgttcg 957301 tgaaggagtc attacatata agatcgctgc gcacgctgcg gaccttgcaa aagggcatcc 957361 cggagcgcaa atccgggatg atgcgttatc gaaagcccgt tttgaattcc gctggcggga 957421 tcagtttaat ttatctcttg atccggagag agcccttgaa taccatgatg aaaccctgcc 957481 tgctgaagga gcaaaaaccg ctcacttttg ttccatgtgc ggtccgaaat tttgcagcat 957541 gagaatttca caggatattc gggattatgc gaagaaaaac gatctcagtg aagcagaagc 957601 cataaataaa ggattaaaag aaaaagcaaa agagtttgtc gatacgggaa gcaatttata 957661 tcaataaaaa aaatgaagat ggagaatgct ccatcttcat ttttttagaa aaacagagag 957721 cgtcgaagcg gaggaatact ctgttcaaag cggaaaacat tttctggatc atatgtcgtt 957781 ttgacacggc ggagtcgttc aacgttttcg ccgtaatatg ttcttggcca gtttctgatt 957841 tcgatatctg gccaatttac gtagtctccc atcgtttctt tcgaaaggga cgttctcagc 957901 ccctcaatcc agcggacatt ttgtcttttt tctccagggg atgtccagtt tgttaagtat 957961 tcctgggcga tgattgcgtc acgataataa aatgccgttt ggtcgggagc gacccgtccg 958021 gctgccccgc cgagtgcttg ctgccagaca ctggcgtttt gattcggagc gtgctctaaa 958081 aagtgtttta ttgttgagat cgcacgttct gataatggct tttcaatgaa agagccggag 958141 cgtttcattt tttgaggctg attgcctccc gggctgttaa aaaaggttac cgcttcaatg 958201 aatggcgttg tttttaccat tccgcttgtc ggacttcctg ctttcaataa aggctttaac 958261 agttttttta actctgtttt tggcccgaca aattggccga gggcttctat gcggtttact 958321 tctttaggcc aaaactctat tgatgatgta agccggtcat ctgtatacgg ggcccagttc 958381 tgccacgtgt tatatacttc ctcaaaatca tcccatcccc atgtaataga aaaaatcgac 958441 acttgagaga tgggcactgc tttaaatgtc atggaggtga ctatgccgaa attgcctcct 958501 ccgcctccct gagacgccca aaataagtct ggatgatttg aacagctgac tgtaatcaga 958561 tcagcgccct ctttttcgtc tgctacgatc atctcaagct gcacgaggct gtcgcaagta 958621 agaccggcag cccttgttaa aagtccaatt ccccctccga gagttaaacc tgtgagccct 958681 acattagcaa tggtgcctgc gggaagcgtc aggccgtatt gccagagtgt ccgatagact 958741 tctcccaatt cagcccccgc ttcaatatag gccagctttt tatcctgatt cacagttatt 958801 tttttcatct cgcttaaatc aataacaaga ccgttattta aaagggaaaa gttctcatag 958861 ctgtgtctgc cgcctctaat acggaaaggc acacggtttt cacgcgccca tttcagcgca 958921 ttgagtgcat cctgtttgtt ttggcaaaac acaatgatgt caggatacct ttctaagctt 958981 aggttaatat tggttcttgc ttcgttatag tccggatcat cccgtgtcac gatacgtccg 959041 gtcaattttg tcttttccac actcccacat ctctttctct cgtattctag tttctctagc 959101 ttatgcgtca ggggaaaaga gtgtataagg aaaaagcggg gatgcaatct gatacagtgt 959161 caacaccctc aaaaaatagt tgacaggtcg gtattgtatg aattaacatg gtcagtacaa 959221 atttttcaaa tttatcgcgc tgatcggaac accgaaggct cttatcgttt agataagggc 959281 cttttttgta tgaaaaaggg gggattattg atgggagtca aaaaagaaaa ggggagaaaa 959341 cgattcagga agcgaaaaac ctacgggaat cagattttgc cgcttgagct gctgattgaa 959401 aaaaacaaac gagagattat aaacagcgcg gaactcatgg aagaaattta tatgaagatt 959461 gatgagaagc atacgcaatg tgtaactaaa tataaaaaaa cccgctgact acaacgggtt 959521 tttgcatttc tccattaaga atctttttta atcggcaatc caaggccttc tgccacgcgt 959581 tttccgtatt caggatccgc tttgtagaag tgctcgattt ggcgcagctt gatttcttct 959641 ttttctaccg gcttcatggc attaacgata ttttcaacaa ggcgggtacg ttcatcttca 959701 ctcattaaac gatacagatc gccggcttga gtgtagtgat cgtagtgatc gtagcttacg 959761 ctgtcagcga taccttgtac cggatatgct gcttgcttat cctcaggtga ctcttttgga 959821 ccgccgaagc tgttaggctc gtaatacaca gatccgccgc cgttatcatc aaaacgcatt 959881 tgcccatcac gctgataatt gtttactttg ttgcgtgcgc ggttgattgg cagcgcttga 959941 tggtttgcac cgacacggta gcggtgtgca tcatgataag caaaaagtcg accttgaagc 960001 attttatccg gtgaaacatc aataccaggc acgagggttc caggtgaaaa tgtcgcttgt 960061 tctacctctg caaagtagtt ttccggattt ctgtctagaa ccatgcgtcc gacctcgatt 960121 aacgggtagt ctttttgaga ccaaactttt gtgacatcaa acggatcgaa acggtacgta 960181 tttgcatctt ctaaaggcat gatttgcaca tatagtttcc atgcaggata atcaccgttt 960241 tcgattgcgt tgaaaaggtc ttctgtatgg taatcagggt tttcaccggc aatttttgct 960301 gccgtattga catcaaggtt tttcacgcct tgttctgttt taaagtgata tttaatccat 960361 acgccttcgc cttcggcatt tgtccatttg aatgtatggc ttccgaagcc gtgcatgtgg 960421 cgaagtgtcg caggaattcc gcggtcagac atcaggattg tcacttggtg cagtgactct 960481 ggtgaaagtg accagaaatc ccatacagcc gtagggtttt tcaggtgtgt ttttggatct 960541 cttttttgtg tatggatgaa atcagggaac ttaatcgcat cgcggataaa gaatacaggc 960601 gtattgttgc cgacgatgtc gtagtttcct tcttcagtat aaaatttaac agcaaatccg 960661 cgcgggtcgc gaactgtgtc agcagagcca agttcaccgg caactgttga gaaacggatg 960721 aacaacggtg tgcgtttgcc gacttcagaa aggaaagcgg ctttcgtgta ttttgttacg 960781 tcgtttgtca cttcaaaata tccgtgtgcg cctgctcctt tggcgtgaac aacacgttca 960841 ggaacacgtt ctcggttgaa atgggccaat ttttcgagta aatgtacatc ttgaattaaa 960901 gttggtccgc gagaaccggc agtcattgag ttttgattat ctccaaccgg agcgccccag 960961 ctagttgtca gtttatttga actcatgtta tcacctcttg gaatttataa gaacataata 961021 tcatctctaa gtaaaaagtc aatattattt tataattatt ataaaatagt tatctctatt 961081 aatcgatata tagtatcgaa attgttgaaa aaccttgttg taacagcttt ttatgacact 961141 taataatttt tggagaaata atttttcctt ctctatttgc gaaacaagca gagtaagtga 961201 taaacaagga tatcaaaaat cgtatttaaa aaagagttga catatcggaa taatttgaat 961261 taacatgtta ttcaaacaaa aaaacaattg ggcagctgat cggaccgccg aaggctctca 961321 tctctacaag aacagagatg ggggcctttt tgtttttttt gaaggcgggg ttggcagaaa 961381 gagagggata aaagtggctg tgaccatcag catcaaagaa aaggcatttg ttcaagaagg 961441 ccgcaaaaac acggtcttag aaaacataga attatcaatc gcaccaggcg aatttctaac 961501 gcttatcgga ccgagcgggt gcggaaaaag caccctgtta aagattattg cagggcttga 961561 ttctgaatat gacgggagtg tggaaattaa cggccgcagc gtaacagctc cgggtattca 961621 gcaaggattt atttttcagg aacaccgcct ctttccttgg ctgactgttg agcagaatat 961681 tgcagccgac ttgaatttga aggacccaaa agtcaaacaa aaggtggatg aactgatcga 961741 gattgtcaga ttgaaaggat cggaaaaagc atatccgcgc gagctgtcag gcggcatgtc 961801 acaaagagta gccatcgccc gggccctgct gcgggagcct gaggtgctgc ttttagatga 961861 accgtttggt gcactcgacg cttttacaag aaaacacctg caggacgtgc tgctggatat 961921 atggaggaag aaaaaaacaa cgatgattct cgtgactcat gatatagatg aatctgttta 961981 tttaggaaat gagcttgcga tccttaaggc caaaccgggg aaaatccata agctgatgcc 962041 cattcacctg gcgtatccgc gaaaccggac gactccggat ttccaagcga tcagacagag 962101 agtgctgtcg gaattcgaga aaacagaaga tttggagtac gcagaaggat cagggatata 962161 gaaagggcgg aagcggaaat gaaaaaagga ctcattgtat tggttgccgt tatttttctg 962221 ctcgcaggct gtggagcaaa tggagccagc ggtgaccaca aacaattgaa ggaaattcgt 962281 attggtattc agcaaagctt aagccccctt ttgattgcaa aagaaaaagg ctggttcgaa 962341 gatgcatttg aaaaagaagg catcaaagtg aaatgggtgg agtttcaaag cggtccgccc 962401 caatttgaag gccttgcggc agacaaactt gatttttctc aagtcggtaa ttcgcctgtg 962461 atcgctggac aggcggcagg cattgacttt aaagaaatcg gtttgtctca ggacggcttg 962521 aaagcaaacg gcatccttgt caatcaaaac agcggcattc aagacgttaa gggcttaaag 962581 gggaagaaaa ttgcagtcgc caaaggcagc agcgggtttg attttttgta taaagcgctt 962641 gatcaagtgg ggttgtcagc taacgatgtg acaattattc agcttcagcc tgatgaagca 962701 gcttccgcat ttgaaaacgg atctgttgat gcctggtcca tttgggagcc gtacttgtcc 962761 ttagaaacaa tgaaacacgg agcaaaaatc cttgtgaacg gagaaagcac agatttatat 962821 tcaccgggtt ttactttagt aagaacaaag ttttcagaag agcatccaga cgaagtggtc 962881 cgttttctga aggtgtttaa taaagccgtt gtatggcaaa aggaacatct ggatgaagca 962941 gcggacttat attctgacat taaagatctc gataaaaagg tcgtcgaaaa tgtgctgaaa 963001 aatactgagc cacttaatga gatcatcagt gacgacattg tgaaagcaca gcaggaaaca 963061 gcagattttc aatttcgaac aaaggcgata gataagaaga ttgatgtgaa ggatgttgtc 963121 gataacactt ttatcaaaaa agcattagag gagcattcct caggaggtga tcaatgatga 963181 aagcagaggc tgcgggctcg ctgcccaaaa cgaatgcgga agcggtgcga aaaaagcccg 963241 gaaggaagag atacggctgg atgaaggggc ttttactgcc cgctgtcatc attgccatct 963301 ggcaggtcat cggcgggctg ggggttgtgt ccgctacagt gctgcctaca cctgttacga 963361 ttgttctgac ctttaaggag cttattttgt ccggcgaact gttcggccat ctgcaaatca 963421 gcatttatcg ggcggcactt ggttttttgc ttggcgcggg gcttggattg atgatcggga 963481 ttttggccgg attttccaaa cggacggagc tgtatcttga tccgtcgttg caaatgctta 963541 gaaccgtacc tcatctggcc gtcacgccgc tgtttatttt atggttcgga tttgacgaag 963601 tatctaaaat tttgctgatt gcgctcggtg ccttctttcc tgtctatatc aatacgttta 963661 acggcatccg cggggttgac gcgaagctgt ttgaagtcgc ccgggtgctt gaatttaaat 963721 ggcatcagca gatatccaaa gtgatattgc cggcagccct gcccaatata ttgctaggca 963781 ttcgcttatc gctcggcatt gcatggctcg ggctcgttgt ggcagagctg atgggctcaa 963841 gctcgggagt cggctatatg atcatggatg cgagacagtt ttcacaaacg aataaagtct 963901 ttgcagggat tatcattttt gcagtggttg gaaagctgac ggattccttc gtcaggctgc 963961 ttgaacgaaa gctgttaaag tggagaaaca gctacgaagg ataaaagata taaaggggag 964021 atgaatatgg aaattctttg gtttataccg actcatggag acgcgagata tttaggatct 964081 gaaagtgatg gacggactgc ggatcatctt tactttaaac aagtcgcgca ggcggcagac 964141 aggctgggat atacaggagt tcttctgcca acgggaagat cgtgcgagga cccgtggctt 964201 acagcgtcgg cactggcagg agaaacaaag gacttaaagt ttttagtcgc ggtaagacct 964261 ggtttaatgc agccttctct ggcagccaga atgacatcca ccctagaccg catttcagac 964321 ggccggctgc tgatcaacgt tgtggcaggg ggcgatccgt atgagctggc aggcgatggc 964381 ctgtttatca gccatgatga gcgctacgag gcaacagacg aatttttaac cgtttggcgg 964441 agacttttgc agggagaaac ggtttcctat gaaggaaagc atataaaagt ggaaaacagc 964501 aatctgcttt tcccgccgca gcaagagccg catccgccca tctatttcgg tggttcgtca 964561 caggctggaa ttgaagctgc cgcaaagcat acagacgtgt acttgacatg gggtgagccg 964621 cctgaacaag taaaagaaaa gatagaaaga gtcaaaaagc aagcggcaaa agaagggaga 964681 tccgttcgat ttggcattag gctgcatgtc attgcccgtg aaactgaaca agaggcatgg 964741 gaagcggcag agcgcttgat cagccacttg gatgatgaca ccattgccaa agcgcaggca 964801 gctttgagcc gttacgactc ttcaggccag cagcggatgg ccgtccttca tcaaggcgat 964861 cggacgaagc ttgaaatcag cccgaatctg tgggcgggga tcggcctggt cagaggaggg 964921 gcaggaacag ctcttgtcgg tgatccgcag acgattgccg accggatagc ggagtaccag 964981 gcactcggca tagaatcgtt tatattctcc ggctatccgc atttagaaga agcgtattat 965041 tttgcagagc ttgtatttcc gcttttgccg tttgaaaatg atcggacgag aaagcttcag 965101 aacaaaaggg gagaagcggt aggaaacact tattttgtca aagagaaaaa tgcatgagtt 965161 taactaaaat acagcccccc gaacatggta tgatattcaa aaaaaggggg ctttttttct 965221 gaaaacattg agaagcgcgg cagtcatttg cctcatagct atgctgtcag catgcggaca 965281 ttcaaaacag atggaaatca aagcggcgga catatcagat cttgaaaaaa acagaatgga 965341 tgtcgcagct tcacaggcat tcactgccga agccgtcaat atcggtgaag gtatttcttc 965401 agctgacatg tacatcgaac attatcaaaa gggaaagctt gttgagaggt ttggaccggt 965461 tcgtgcagat tattcagagg aaaaaactga taccatacaa tttgtttatt ttgagaatga 965521 agagggggaa ggaaagaata aacataccac cattcatttt ggcattgtgg ataaacaggg 965581 aactatagcg gctgattcat cggtgaaacg cgacgatagc acaacacagg aaatgactca 965641 gaatatttca tcgccggaac cgattacttt cgagaagcct gctttgatcg gcagcagtat 965701 tagagggact gacgagacaa tgcacacctc tgaacataaa aaagagctca ttaagcatca 965761 agatgcgtta ctgtattatg tggaattgca tcattagaat gggcggcttc aggccgtctg 965821 ttttacaaag cggtatgctt gcttttttga atggtgaatg atacatttta aatcgtaaca 965881 atttcgattt aaagggaggc tatgtgactt ggctaaaaaa tcaaaagtgg caaaagagtt 965941 aaaacgccaa cagcttgttg agcaatacgc tggtattaga cgcgagttga aggaaaaagg 966001 agattacgag gcactcagca agctgccaag agattcagca ccgggaaggc ttcacaaccg 966061 ctgcatggta acggggcgcc cgagagcata tatgaggaag tttaaaatgt ccagaatcgc 966121 tttcagggag ctggcccata aaggccagat tcccggtgtg aaaaaagcaa gctggtaaga 966181 aaaaactccg gccgattaca gcgcgccgga gtttttttcg tttttcttga aagagatgac 966241 gtaggaaagg tgctggatga tcatgatgat aaacacaata ataataggga aaaacggaat 966301 gcgcgattga aatagcggat aaaaaatgag aagaaccgct gcggcaggca gcgagaagta 966361 gacagcgata tatgacgcgc gacatgcttt tgccgtcatc atctgctctc tttcatcctg 966421 ctcttcaaac tcatcaggca gaagtagctg ctttctggca gggcggcttt ttttctgtaa 966481 gtacaaataa accgcagacg ccgcaacaaa cagaataaag ggagtgaggt ttaaatcaaa 966541 taccatcccg ccgctctttg tgccgaaaaa agatgctatg ccttctgagg cttcaaagta 966601 tgaaatcagc gcccagcatg caaggccaaa taaaacaagg tgaaaagctg cttttgtttt 966661 catgctcatc ttagttttcc tcctctaacc aaaagacatc ctccattttc atggagaagg 966721 ctttgcagat tttcagtgct aacagcagtg agggaacata atcgcctttt tcaatcgctg 966781 ccacagtctg tcttgtgacg ccgaccgttt ctccgagttt ttcctgagaa tagccgaagc 966841 gtgccctcag ctcttttact ttatttttca tcatgacgtc tgtccccttc acaatctcga 966901 ttgattatat tgtatagtat acttaacatt atgtaaatgg aacttaacaa ctttacaaaa 966961 agataacttt ttttcgacaa aatttttata ttcccttgac gaaaaataaa taaacatgta 967021 atataaaaaa agtcagagcg gtactgttgc tgacaatcac aaatgcgggt gtagtttagt 967081 ggtaaaacct cagccttcca agctgatgtc gtgagttcga ttctcatcac ccgctccata 967141 catacgttat taacgcagtg tttcgtttct cagataaacg aagtattgcg tttttttatg 967201 tgaaaaagaa cacggtattc gtgttctttt acgtaagcca atgtactgta tgggtgccgc 967261 cgtgaatttg ttcaaacatt ttcgttaatg atgataagag gttaacagcg ctgcttttct 967321 caatcgatgg cgggaaaaaa atgatttgca gcatattctt agtctcgttt gaaacgggat 967381 agtggttgac gctgtttttg aaatcgccaa aaatgccgtt ttcatcagag aaaagcagta 967441 tgttttcttt ttctcccaat gagatccgga ccggctcatg aagctttccg gcatcataaa 967501 tcataatagg cagagaatat tttaatgcga aaaaatcgat tgtgtcatgg gccgagtctt 967561 tactttccat gaattgttcc ttggatatcg ggaccagcat gtcctccatt ggggttgttt 967621 ctccctcaaa tgaagggtta agctgtttaa agagtttctg ccattccttg acgaaggatt 967681 catcggatat accgccgtcc gcatagtcga aaaacaagga ttcttgaaac aggcggagtc 967741 tgcctttcag catttgcggt gaggagccga cttcgatatt ctcataaatg acagcagctg 967801 catgtaagcc ggccgcacgt tcagtaataa cagaatcaag tttgatattc actagcattc 967861 actccagtta cgtgatatca acctattata aacgctgtgt cgttttatca caaagaaagg 967921 aggctgtgca aaacatgaac gtttatcagc tcaaagaaga attaattgaa tacgcgaaaa 967981 gcattggcgt agacaagatt ggttttacga ccgctgatac ttttgacagt ttaaaagacc 968041 gtttgattct tcaagaatca ctcggctatc tctccggctt tgaagagcca gatatcgaaa 968101 aaagggtgac gccgaagctt cttttgccga aagcgaaatc aatagtggca attgctctcg 968161 catatccttc cagaatgaag gatgcgccga gaagcacgag aactgagcgc aggggcattt 968221 tttgcagagc ttcctgggga aaagactatc atgatgtgct gagggaaaag cttgatctgc 968281 tggaggattt tctaaaaagc aagcatgagg atatcagaac gaagtcaatg gttgatacag 968341 gtgaattgtc tgatcgcgcc gttgcggaac gtgccggaat cggattcagt gcgaaaaact 968401 gtatgatcac aacacccgag tatggctctt atgtgtattt ggcggaaatg atcacaaata 968461 tcccttttga gcctgatgtg ccgattgaag atatgtgcgg gtcctgcacg aaatgcttgg 968521 acgcctgccc aacgggagca ctggttaatc ccgggcagct taatgcgcag cgctgcatct 968581 cttttctgac ccagacaaaa ggatttttgc ctgatgaatt ccggacaaaa atcggaaacc 968641 gcctgtacgg gtgcgatacg tgccaaacgg tatgccctct caataaaggg aaggattttc 968701 atcttcatcc ggaaatggag cctgatcctg agattgccaa accgttattg aagccgcttt 968761 tggccatcag caatcgggaa tttaaggaga aattcgggca tgtctcaggt tcttggcgcg 968821 gaaaaaaacc gattcagcga aacgccattc tcgcgcttgc ccattttaag gatgcttccg 968881 cactgcctga attgacggaa ctgatgcaca aggatccgcg tcctgtcatc agggggacag 968941 ccgcatgggc aatcggaaaa atcggagacc ccgcctacgc ggaagagctt gaaaaagcgc 969001 tggaaaaaga gaaggatgaa gaggcaaagc tggaaattga aaaaggaatt gagttgctaa 969061 aagcttcagg catgactaaa caaggcctgt cctgacatac gtatagagca gaaggaaaaa 969121 acacttgaga tcatccaagt gttttttctc tataaaaaag tatggcgggt ggggtgagct 969181 tgaagtacat tttagaacaa ttagcggagg agcggctggg ctttctggtt aacgggcatg 969241 ctatgagaca ggagtctcaa gtcggagacc ttaaagtcat ggagcgtaag aaaaagcttc 969301 tggaaaaacg taaagttgac atcataaaag cgaaagcaaa ggccgtgatt aatcatgtgc 969361 gggttgagga tgacggaacg acctgccttt cgtataccat ccattacgaa tacgtgtgta 969421 aggaacaaga tgacagcttg tatatagaag agcacataga ggagcgaatg gctttcctgt 969481 atgatcacat tttgattagt gatcaggaaa ttgcgaaaaa gccggctgga tttcatgaag 969541 ggaccagtat tattgactat tctgaagctg aagaggaaag agaagcgttt ggcagggctt 969601 ttcaatacga tcgtctcggc gctgtccaat atgccgagaa attttggaac aagcgcaatc 969661 ctgcttataa aaatttcagc gataactgta caaattttat ttctcagtgt cttcatgcag 969721 gaggcgcgcc gatgcgcggt catccgaaca ggggatcagg ctggtggatg aaacaaagct 969781 catggagcta cagctggacg gtggctcact ctatgaaaat gtatttgtcg aattcaaagg 969841 ccggactgcg tgcggtgcgg gtgaaatcag cggaagaact gatgccgggc gatgtgattt 969901 gctatgactt cgaaggagac ggccggttta atcatacaac gattgtcgtg gcaaaggaca 969961 aaggcaatat gccgcttgtc aacgcccaga cttatgacag caggatgagg tattggtcat 970021 atgaggattc tacggcatac acgccgtcaa tacgatatgc cttttttcat atcgttgatg 970081 atacgacaaa agagtaatta atgttataat gatgggcgga taagaaaaac agaggtgaac 970141 attgtggcat tacatgtcgt tttatatcaa ccagaaattc ccgctaacac agggaatatt 970201 gcacgtactt gtgcagcaac caatacaacg ctacacctga ttcgtccgct cggcttttca 970261 acggatgata aaatgctgaa gcgtgccgga ctcgattatt gggagtttgt taacgttgtg 970321 tatcatgatt cgttagaaga attgtttgag gcatataaaa aaggcaagtt tttctttatt 970381 acaaaatttg gccagcagcc tcatacatca tttgattaca ctgatcttga cgaggattat 970441 ttcttcgtgt tcggaagaga aacaagcggt ttgccaaagg atttaattca aaataatatg 970501 gaccgctgcc tgcgtcttcc gatgacagag catgtcagat cgttaaatct gtccaatact 970561 gccgcgattc ttgtttatga agcgctgcgc cagcaaaatt accgtgattt aaaatagtga 970621 aaaacccgct catcgatgat gggcgggttt ttttgcggat gttgaaatgc tttgtttcgt 970681 ttttgggctt aacaacgtaa cagtgttatg ttacaatgta cccatcaaag gagctggact 970741 tatggaagaa caattaatct ctaaaaaaga attacttgaa agaacatcga tttcatacgg 970801 tcagctgtat cgatggaagc ggaaaaactt aatacctgag gaatggttta ttcgtaaatc 970861 cacatttaca gggcaagaga cgttttttcc gagagaggag attttaaaac gtatatcaat 970921 gattcaaaag atgaaagaaa atttgtcttt ggatgaaatg agggaaatgc tgtcgccgaa 970981 aatgaaggat gtcagcatga ccgctgatga attgcttcat aaaggtttgg tttcaaggcc 971041 tgctcttgaa gcctattcag aagacggagg aagtccggtt ttttcatcca gcgatttgct 971101 ttcgctgttt gtgcttgagg gcctgctgca gtctggaaat gtcagccttg cagaagcaaa 971161 aatggctgca gaggtattaa agaagcatga tactgaagag attgaaaaac agacggagct 971221 gattgtgctc cgcaagctcg gtgtcacaac ttgttttata gcggctgcgg cggacagcat 971281 tttgtttgaa tcatccgtaa aggttgtgga acgggtagat ttattaaaag cttcagagga 971341 attaaaaaca acatttatgc aggagggcca tcaatggatg tagtggaaaa gctggtgata 971401 aatggatcag gaagttctaa gggaggaaca tttcaatcag ttgagattaa tggcagcggg 971461 acagtggccg gggacgtgga gtgtgacact ttttctttta atggaaacgg aaaagcggac 971521 ggcagcgtca aagcgaaagc ggtaactatc agcggttcag gaaagataca tggagacgtt 971581 gaagcagaat ctatccggat gaatggcact ggttttattc aaggagaggt atctgcaaaa 971641 caattgaaaa tcgctggatc atcaacattt ggcggcactg tcaaggctga tggaattgac 971701 attagcggaa aagctgtcat ggaagcagat tgtgaaacag aaacctttca atcagaaggg 971761 aaatgcaaaa tcagcgggct tttaaatgca gaccaggtga tcattaagct ttctgcaggg 971821 gaaagctatg cgcgggagat cggctgccgc catcttcaag tgacctgcag aaaaggaatg 971881 ctgacattgc tcagattgat gccgcagcct gttctaacag cagagctgat cgaaggtgac 971941 gtgattgaat tgacaaatac aaaggcgaaa accgtgcgcg gtaataaagt gatcatcggc 972001 ccggattgcc agattgaaac cgtcgaatac agcggggact atacctgtga tccaagcgcg 972061 tcggttgaaa catccacaaa gttgtaagga ggatcgtaat ggagacaaca aaactgggaa 972121 atttaaaatt atatggcgct gggcatgccg caggaggcgc gtatcacaat gtcagcatca 972181 aaggagaagg tatagttgga gaagggctgt ctgctgtagg ctgccgcata tacggaacgg 972241 gcctttttct cggaaaagca gagactgagc ggctgcgtgt gctcggagaa agtgaatgta 972301 aaggcgatct gacagccggc aaaatcaata tatatgggac aatgaaagtc agcggctcac 972361 ttcaatttga tcgattcaat ctgaaaggcc agactgaaat tggcgggaat atgactggag 972421 aatcctgcga tgtgaaaggg aagcttagcg taataggtga ttgtgaaaca gaaatgttcc 972481 atgtcacagg ctgtgttgat gtatcggggt tattaaattc gggtgagatc aagctgggat 972541 tgagccatga tataagccat gtgcaggaaa tcggcggaac aacaattaca gtgaaaagac 972601 gcgcgagttt ttttagccgg aagaaaggga agctgatcgc cgatgtcata gaaggagatc 972661 gggtttattt ggagaatacc gaagcggcag ttgtcagggg aaaagaagtg atcatcgggc 972721 cgggatgcag catcggaacg attgagtacg aatacaaatg tgaatgcgat ccgcattcac 972781 agattaaaga aaaaacaaaa ctgtaaaaca ttgttctgtt atacaaaaag ggtgctcttt 972841 caggagcacc cttttttatt cttttccagg cttgctttcg tatcctgcgg taaaaattga 972901 tactaaaaaa gtgacaatga cacccatcat gatgattgtt ttcaccgtct ctccccctct 972961 tcaatttttc cgtgctgtcc gagtctggat gattctgtat ttttctttat tatgaacggt 973021 cgcagtctgc cttgtcaacg atgtatgagt atctttattt ttaagaaacc aaagcatgta 973081 tcacgagatg gcggcataga ttgtatcaaa gtaccttatt tgcatagtgt atcaaacatg 973141 atagaggagg tccttatgga tatattaaag aaaattgaaa agtacagaga ggaagagcag 973201 cggctgaaat gggaaggaac tttcgccgat tatttggaga ttattaaaga aaatccgatg 973261 gtcgcgcaat ctgctcattc tcgagttttt aatatgataa aagacagcgg gatagaggag 973321 attgacggac gcaagaagta cagttttttt gaccgcgagc tgttcgggct tgaagaatct 973381 ctggagcgtc ttgtggaaga gtattttcat ccggctgcca aacgtctaga tgtcagaaag 973441 cggattctat tgctgatggg gcctgtgagc ggcggtaaat ccacgctggt cacaatgctt 973501 aaaaaaggtc tcgaagcgta cacgctgaca gataatggcg ctgtatatgc gattaaaggc 973561 tgcccgatgc acgaggaccc tctacattta atcccccatc atttacgcga tgacttttac 973621 agagaatacg gcattagaat agaaggaagt ctttctcctt taaatgtcat gaggctggag 973681 gaagagtacg gaggaagaat tgaggatgtg aaggtggagc gcatcttctt ttcagaagat 973741 aagcgtacgg gaattggaac attcagtccc tctgatccga aatctcagga tattgccgat 973801 ttgacgggga gtattgattt ctcaacaatc gccgagtacg gttcagaatc agatccgcgc 973861 gcttatcgat ttgacggaga gctgaataaa gcgaaccgcg ggatgatgga gtttcaggag 973921 atgctgaaat gtgatgagaa atttctctgg catttgcttt ccttgacaca ggaagggaat 973981 tttaaagctg ggcggtttgc gttaatttct gctgatgagc tgatcgtggc tcacacgaat 974041 gaaacggagt atcgctcatt tatttctaat aagaagaatg aagccctgca ctcaagaatc 974101 atcgtgatgc cggttcctta taatttaaaa gtgtctgagg aagagagaat ttatgaaaaa 974161 atgattgcag aaagcgatgt ggcggatgtt catattgccc cgcatacgtt gaaggtcgcc 974221 gcgatgttct caatccttac ccggttaaaa gagccgaagc ggtcggatat tgatctggtc 974281 aagaaaatga gactgtatga tggggaaagt gtggaaggat ataactctgt cgacgttgag 974341 gatatgaaaa aagaatataa tgatgaaggc atgagcggaa ttgatccgcg gtacgtgatc 974401 aaccggattt cttcaacgat tatcagaaaa aatatggaat cgattaattc tctcgatgtc 974461 cttcgctcct taaaagaagg tcttgatcag cacccatcaa tttcaagcga ggacagggag 974521 cggtatttga attttatctc tgccgcccgc aaggaatatg acgatattgc gaaaaaggaa 974581 gttcaaaaag cgtttgttta ttcatatgaa gaatcagcaa aaacacttat ggacaattac 974641 ctcgataacg tagaggccta ttgcaataaa aacaagcttc gtgatccttt gacaggagag 974701 gaaatgaacc ctgacgaaaa gctgatgaga tccatcgaag agcagatcgg catttcggaa 974761 aacgccaaaa aagcgttccg cgaagaaatt ttaatccgca tctcggccta tgcgagaaaa 974821 ggcaagcggt ttgattacaa ttcccatgaa agactgcgtg aagctattca gaaaaagctg 974881 tttgctgatc tgaaggatgt cgttaaaatt acgacctcaa caaaaacgcc ggatgagcag 974941 cagctgaaaa aggtaaatga agtcgtggcc cgtttaattg atgagcacgg ctacaactcg 975001 acgagcgcca atgagctgct gaaatatgtc ggcagcctgc tgaaccgata agcaacgtga 975061 cccgtccgaa tagggcgggt tattttgtcc cattttctaa atagtttgtc aattaaacgt 975121 gcatatgtgc atatgatgaa tataaatctt ttcaaaagac ttgtttcata atctggcaca 975181 agccggaata cgtatgtatc acgaccacaa atggttaagg aggggaattc atgtcccaaa 975241 atgacagcgg ccattttttg atttctgagg aaaactggtc cctccatcgc aaaggcttcg 975301 atgaccagca gcgccaccag aaaaaagtgc aggaagcgat caaaaacaat cttccggacc 975361 tcgtaactga ggaaagcatt attatgtcta atggaaaaga tgtagtgaag atcccaatcc 975421 gttcacttga tgagtataaa atccgttata actatgataa aaataaacat gtagggcaag 975481 gagacggcga gagccaggtt ggagatgttg tggcccggga tggatcagac aaaaaacaag 975541 ggcctggaaa agggcagggt gccggtgatc aggcaggcga ggattattat gaagcggaag 975601 tttcattaat ggatttagaa gaagcgcttt ttaaagaatt agagcttccg aatctccagc 975661 aaaaagagcg ggacaatatc attcatacag atatcgagtt taatgatatc cgtaaaacag 975721 ggttaaccgg taatattgat aagaaaagaa cgatgatgtc agcctttaaa cgaaacgcaa 975781 tgtcaggaaa accgtcgttc tacccaattt atccggagga cctgaaatat aagacgtgga 975841 atgacatcac aaagcccgaa tcaaaagccg tcgttttagc catgatggat acaagcggca 975901 gtatgggggt ttgggaaaaa tacatggcca gaagcttctt tttctggatg acccgttttt 975961 tgcggacaaa atacgagact gtggaaattg aatttattgc ccatcataca gaagcaagag 976021 tggtctcgga ggaggatttt ttctcaaagg gagaaagcgg cggaacaatt tgttcttccg 976081 tatatcggaa gtcgcttgag cttattgatg aaaagtacaa tcccgcccgc tataacattt 976141 acccgtttca tttttctgac ggtgacaacc tgacatctga taacgcgcgc tgtgtgaagc 976201 tggtcaatga tattatgaag aaggccaatc tgttttgcta cggcgaggtc aatcagtaca 976261 acaggcattc aacgttaatg tctgcatata aaaatgtaaa agatgagaaa tttaagtact 976321 atattttaaa acagaaatct gatgtttttc aggctctaaa gaactttttc agaaatgaag 976381 agtctggtgt aagccatcaa ttttcgtaat gaaaagccca tttcagggct tttttttatt 976441 taataaaagc aagaaaacgc ttgcgaaaaa aatacgggag aaaaagaaat ttttcctttg 976501 acaaatcttc tttcatttat taatatttta tcttgtgaac tattattgag gaatgaggtg 976561 aaaaggagtt gactgaatca gaacgtgctt tgctcacttt tgaacagctc ttcgatacgt 976621 ctcgggcgat atataaaaaa cagaagaaga tattggagat tgtgcttgag ccttttgata 976681 ttacagtcct tcaatatttg ctgatgttta aaattcatca aagcggaagc accccgctaa 976741 gcaagctggc aatgtcgctt gatcttaagc ctgcttctgt gacgcggatg acagatattc 976801 tgtataagcg ccaattgatg aatcgatatg acagtccgga tgaccgccgt atcgtcatga 976861 ttcagttaac cgaagagggg gaagaactga tagaaaaagc cgctgtgcaa tatgcaaaaa 976921 tgggtgctgg cttgtaccaa aagcttgata cctcccagct gcagtatttg cgcaaactag 976981 ccggaagttt aacgaagctt gctgaaggct gttcagaaaa aagcggtaat taaaaacttc 977041 tcacatattt tcaccagctt tccgcaaaat gatagaggat gaaacgaaag gagaaaacaa 977101 aatgaacaga ggacgtttaa ttctgaccaa cattatcggt ttgattgttg ttcttgcaat 977161 tatagctgga ggtgcttact actattatca aagcacaaac tacgtaaaaa cagatgaagc 977221 aaaagtagcg ggcgatatgg ctgctattac tgctccagca gcaggtaaag tatctgactg 977281 ggatctggac gaaggaaaaa cagtgaaaaa aggcgacaca gttgcaaaaa tcaaaggtga 977341 acaaactgtt gacgtaaaat ccattatgga tggcacaatt gtgaaaaacg aagtgaaaaa 977401 cggacaaacc gtacaagctg gtacaacaat tgcacaaacg attgacatgg acaacctata 977461 catcacagca aatattaaag aaacagatat tgcggatatt gaagtaggaa atagtgtaga 977521 cgtagtagtt gacggagacc ctgatactac atttgacggt actgtagaag aaattggtta 977581 tgcgactaac tcaacttttg atatgcttcc ttctacaaat tcaagcggaa actacacaaa 977641 agtaacacaa aaagttcctg tgaaaatttc aatcaaaaac ccatctgata aggtgcttcc 977701 tggaatgaat gcatctgtta aaatttctga gtaaaacaga tcagtcatca aaccatgaaa 977761 ggaggttgtc ttagatggct acaggcaaag aaaaaaatgc aaaaaaccct atgtcattgc 977821 tgattgtgct aatggcgggt ttatttttgg caattctaaa ccaaacactg cttaatgttg 977881 caatgccgca cttaatgact gaatttggcg taagtgcaac gacgattcag tggctgacaa 977941 caggttacat gcttgttaac ggtgtattga ttccgttatc tgctttcctg attacacgat 978001 ttggccagcg gagtctcttt ctcgtcgcga tgttttgttt tacgctcggt acgttagtct 978061 gcggtatcgc acctaacttc tctacaatgc tgatcggccg tttgattcag gccgtgggcg 978121 gaggtatctt gcagccgctc gttatgacaa ccattctgtt aattttcccg cctgaaagca 978181 gggggaaagg aatggggatt ttcgggctag cgatgatgtt tgctccagcg gtcggcccga 978241 ctctttccgg gtggattatt gagcattata catggcgcat tatgttttac ggacttgtgc 978301 cgatcggcgc aattgttatc attgtggctt tcttcatctt taaaaatatg gtggagccgc 978361 aaaaaatcaa actcgatact cttggcgcaa tcctctcgat tgtcggattc gcctccttat 978421 tatacggagt cagtgaagcc ggatctgacg gctggaccga cccgattgta ttgtctacag 978481 ttattatcgg agccattgca attgttgctt ttgttgttca gcaattgcgt catgatgatc 978541 cgatgcttga tttcagagtg tttaaatatg acattttctc actctcgagt gtcattaata 978601 tcattattac agtggcactt tacactggta tgttcctttt accgatttat ctgcaaaacc 978661 tggtcggctt tacggcgctt caatccggtc tgcttctgct tccgggtgcg atcgttatgc 978721 tgattatgtc accgatctca ggtattttgt tcgataaatt cggaccgaga ccgcttgcga 978781 ttatcgggct tctcgtgaca gtggtaacaa cgtatcaata cacgcaattg acaattgata 978841 caccatatac acacatcatg ctgatctatt caattcgtgc atttggtatg tctctcttaa 978901 tgatgccagt catgacagcc gggatgaacc agcttcctgc ccgtctgaac agccacggaa 978961 cggcgatgag taacacgctt cgccaaatca gcggatcaat cggaacaagt ttaattacga 979021 cgatttatac aaaccggacg acattccatt attcacaaat tgcagataaa acaagcacgg 979081 cggacccgaa cttcctccat gcgttccaaa atgcagtttc gaatttaatg gtgaatatga 979141 atgtgtctta tgatacggcg aaaacatatg tgtactcaca tatttataaa cacgcatcac 979201 tcgattccaa tgtcatgggg ataaatgatg cctttatgtg ggcaacctta ttctgtgtag 979261 caggtttgat tttaagtatc ttcctgcgtg acgtcagaaa agataaattg cgtaagaaga 979321 aaaaagagga gctttcatta cttcctgctc caaaagaagc taaggaatct taatctgtac 979381 agggaggttt cctgaatgaa aatttatgta gtgtatgata gtgaaggcga acatactaaa 979441 gtgcttgcag aagcgattgc tgaaggcgcg agagaaaacg acgcggctga agtgttcatc 979501 gaccatgtag atcaggctga tatccgcaag cttaaagata tggatgcgat tatttgggga 979561 tgcccagggc atttcggaac aatcagctcc ggtcttaaaa cttggatcga cagacttggc 979621 tacttgtggg ctgaaggcga gctgatcaac aaagtcggtg ctgtcttctg cacaacggca 979681 acaacacacg gcggcttgga aatgacaatg cacaatttaa tcacgccgat gttccaccaa 979741 ggcatgattg ttgtcggact gcctggcaac gtgcctgaaa acgcacttta tggctcttat 979801 tacggagcag gtgtcacttg tccggtagac agtgatgagt taatgtctga ggaaggtatt 979861 cagcttggac gcgcgttggg aagacgtgtc agccaagtca caggaaacct aacagcagga 979921 cagtaaggag aggttgaaat ggccattatt atagcaataa ttgctgctgt cattgtcatt 979981 gcggccctta ttacatttaa cgtccgcaac gcctcacctg gacctgagaa gcaagaagca 980041 accgatagaa tcgcacctcc agaagaggaa aaaaacgaag cgcattaccc tgctgaagca 980101 agggctgccg agcatacgcc atccgttgtc aaaaacgatt ctccaaaaga gaagcgtgac 980161 acaatgggtg atgatattta caggcaggcg ctgcaaaagt ttaagcattc tgatgaagtt 980221 catgcagaag aagaggtcac tgaggaaagt gacaaaatgc aggaccgcag ctatcgtgat 980281 gcgctgctct ctatgaaaaa taagaaaaag taatgaaaaa ggcaaatccg tttactcatg 980341 cgggtttgcc ttttttgctg tttccatcaa ttatgttttt atcaaataaa tccatggaat 980401 atgttgtatt ccaccttgat ctagtgtact atgttactca tacaccgagg attttttccg 980461 ggaggtaaag acatgaattc ttttttaggt ttattaaaga aagatatcaa gctttcaaga 980521 atgtggctgc tagtatggat atgcggaatc attttcttat tgggaacagg ccatattata 980581 gcttctcgca cgaaagaacc tctagtcatt tttggttttt ttgttgcagt tgcttttttt 980641 ctgcttttct tatctcctgt ttttgttttt tatcaccttc gcaaggaagg gaaatcacag 980701 ctttggctgt acaatccaaa tggcggctta tggctgtttt cttctaaatt ggcagcatct 980761 ttgctctatc aatttgtgat tcagttggca ttaacagcct atggcatatg gatgtatcat 980821 atgctctctg taaaaaatct gctggagcat caagttgata taacgagtac agtggctttg 980881 ctgaatatgt atgggcttat ttcttcgtta gatatgtcag taacagtcat tgtgttttgg 980941 actgtttttc actctctcag aaattggcgc ggaatgcggt gggctgcgat ggttctgttg 981001 gtcgcaatgt ggttattctt cgatgaatac atcataagcc ctttggttga atctcaaaag 981061 catttctggc ctgtaacagt ctattgcaat tttgatttcc acttccacaa tgtttggaga 981121 ttggaactaa aacctatcca tctgtctgtg ctagggtttc ctattgctat agtcatcaca 981181 ttcttgctgc tcatcatggc ttcaaaactg cttgatcgta aagtagaggt gtaaatatgg 981241 acaatcaatt ccaatcctcg aaaccgattt atctgcagat cgctgatcag atcttttata 981301 ggctggtcag gaaggagctg ctcccaggag acaagcttcc ttcagtaaga gaaatggcga 981361 ttcaaactaa agtaaatccc aatacaattc aaagaactta cagtgagatg gaaaggctgg 981421 gtattgtgga gacaagaaga ggtcaaggga cgtttattgc ggaaaaagca gaaatcgtag 981481 acgagctgaa agacaagctg acacgagagg tgctggaagg ctttgtcaag caaatgaaag 981541 agctggggct aacgaaagaa gaaatgttag aagggattaa aacattcaca gagggaggct 981601 aaaatggaaa tcaagctaga acatgtatca aaaaaatacg gccgccatac ggccgtcaat 981661 gatgtgtcaa tcaccctatc atccggacgg atttatggcc tgattggacc gaacggcagc 981721 ggcaagtcaa cgaccctgaa aatgatggct ggccttctgt ttccgacttc aggatttgta 981781 aaagttgatg aagagcaggt tacgagagaa atggtgcgtc aaacggctta tcttactgag 981841 cttgatatgt tttatccgca tttcactgtt aaagatatgg tgaattttta tcagtcgcag 981901 tttcctgatt ttcatacaga acaggtttat aagctattga atgagatgca gctgaatccg 981961 gaaaaaaaga tcaaaaagct atcaaaagga aatcggggca ggctgaaaat cgttcttgct 982021 ttagcgagac gggcagacgt catcttgctt gatgaacctt tttccgggct tgatccgatg 982081 gtcagggatt ccatcgtaaa cagccttgtg tcgtacattg attttgagca gcagattgtc 982141 gtgatcgcga cacatgaaat tgatgaaatt gagactttgt tagatgaagt aatcatcctc 982201 gccaatggag aaaaagttgc gcagcgtgaa gtagaagata ttcgtgaaca ggaaggcatg 982261 tctgttttgc aatggtttaa atcaaaaatg gaagtttgct agaaagagga ggaatatgat 982321 gaaaacagtg ttggaattga aaaacgtgac taaaaacatc agaggccgaa cgatcattga 982381 tgatctcagt tttacgattc gtgaaggcga ggtattcggt tttttaggac caaacggagc 982441 ggggaaaacg acaaccatcc ggatgatggt ggggttaatg aagctgtcga aaggtgatgt 982501 cctcatttgc ggccaatcaa ttacgaaaga atatgccaag gcgattaagc atatcggagc 982561 gatcgttgag aatcccgagc tgtataaatt tttgagcgga tataaaaatc tccagcaatt 982621 cgcaaggatg gtcaagggtg tcacgaagga aaaaattgat gaagttgttg aactggtcgg 982681 tttaacagac agaatccacg acaaggtgaa aacatattct ctggggatga gacagcgtct 982741 tggcttggca caatgccttc tgcacgatcc gaaagtgctg attttggatg aaccgacaaa 982801 cggccttgat ccggcgggga tcagagaaat cagagatcat ttaaagaagc tgacccgaga 982861 aagaggaatg gctgtcatcg tttcaagcca cctgctgtca gaaatggaac tgatgtgtga 982921 tcgaattgcg attctgcaaa aaggaaagct gatcgatatt caaaatgtaa aagatgaaaa 982981 cattgatgag aatgatacat atttcttcca ggttgagcag ccgagtgaag ccgctactgt 983041 tttaaatcag tacgatttgc tgagtaagac aaatggtgta gaaatcaaac tggctaaaga 983101 ggaagtccct gcggttattg aattgctggt gatgcagcaa atccgtattt atgaggtcaa 983161 ggtcataaca aaatcattag aggaccgttt cttagaaatg acaggtgaaa caaaagagga 983221 ggttcagcat gcttaatttg atttataatg agtggctcaa aattttcagc cgtgccggaa 983281 catgggtgat gatcggaatt ctggggctga caatggttgg atttgcattt ttggcgaatc 983341 atttttctgc cggtgaatca aattcccatt ggaaacaaga gcttcaagca caaaacgccg 983401 aattaaagaa agaaatcaaa gaagatcctt cactgaaaga tgggtataaa gaaacaatca 983461 cactcaatga ctatcgcatc gagcataata tccctagtga cacgggctat acggtatggt 983521 cttatgtaac ggattcagca aactttacca tccttaccgg tctgtttact attatcatcg 983581 cggccggaat tgtcgcgaac gaatttaatt ggggaacgat taagctatta atgattcggc 983641 cgctcagtcg ttttcaaatt ttgatgtcca aatatattac agttctcctg tttgggctcc 983701 tgttgctgtt gattttattt atcggttcta ctttattagg gttgatcttc ttcggaacgg 983761 gtggtgaaac cgccgcgaat attcatttaa tctataagga tggccatgtc attgagcaaa 983821 acatgatggg gcatttggct acaacgtatc tttctgaatc cgtctcggct ttaatggtgg 983881 cgacgatggc gtttatgctg tctgcggtat tcagaaacag ctctcttgcg gttggttttt 983941 ccatcttctt gttggttgcc ggtacgactg caactgcatt tattgcagcg aaatttgact 984001 gggcaaagta tatattgttt gctaatgtcg acttgactca gtatgtggat ggcacaccgt 984061 taataaaagg gatgactatg acgttttctc tcgtcatgct ggcgatctac tttatcatct 984121 tcctgttgct tgctttcgga atcttcatga agcgggatat tgcaaactaa taaaaaaagc 984181 tgttttgctt atgcaaaaca gcttttttgt caaaataaaa actgcaggtt tgcacctgca 984241 gtttttcata tcaatttatg cttacgcttc tttagtaacg ttagcagctt gtggtccgcg 984301 gtttccttca acgatttcaa aagaaacagc ttggccttct tctaaagttt tgaagccttc 984361 gccttgaata gcagagaaat gaacgaatac atcgtcttga ccttctactt cgatgaatcc 984421 gaaacctttt tcagagttga accattttac tttaccttct aacatgaaat ttcctcctaa 984481 agcgatcata acgcttaaat tcactattct tgctcttaac aaactttcaa gacgaaaact 984541 cttacaaaac tttcttctta aagatagttc gaacaaaaat aattaccttt actctaccag 984601 taatcttcag aaaaaacaac tgcttattga aatttttttc ggaaaatacc atatttattt 984661 ttcaatttga tatttattta cggaaattca tctgttttct cgatatgtga tcatacgttt 984721 gccttagtat tccttcattt tgggaagata agtaatagga attgacaacc ttattggata 984781 tgagtaaggt aaaagttaat caatattaca aatgacaacg tttatcaact aagagagcgt 984841 atgattttta tgtctgatat tgcttgcatg ctctaataca tagataggag tatggtcaca 984901 atgaaaaagt ggcttatatg cagtttcgtc cttgttcttc tcgtttcatt tactgcatgt 984961 tcaccgtctg cagaacatga atcgataaaa atcgggattg ctgagtctga cggggcaata 985021 tggaactata ttgctcaaaa ggctgaagag gcagggctgg atattcagct gatccctttt 985081 tctgattatg cggagtctga tatcgcactt gctaacaaag aaattgatgc caacgccttt 985141 caaaccattt catattttca gtcgttcact gaaaaataca aacttaattt ggcaccgctc 985201 gggacgacat acataacgcc catgggcatt tattcaaaac gatatgaacg aatccgagat 985261 atatcgcggg gagctgtcgt ttctgttccg gataaagcgt tcgattttgg cagggcgctt 985321 acggtgctcc aggaagcggg tttgctaacg ctgaaaaacg gatttaacgg aacaggttca 985381 gttgatatga ttaaagataa tccgagacac ctgaaattaa aagctgtccg gcaacaggat 985441 gcagtgagcg gtgccgacgt gtttgtcatg aaaccatcag aagcaaaaaa agcgggcttg 985501 aacccgaaaa agcatacgct aaagagcggc ggactcatgt ctgaggaaga gatgaatttg 985561 attgttgtca gagcggagga tcaagatcgg gaagcgctgc aaaccattct tgagctttat 985621 caagctgatg atacagcggc atttatagaa aaagaatatc agggagatct tgtcccggct 985681 tttctgcctt tgaaacgtct ttcagattgg aagaatgaat tcgaacattg aattcattct 985741 tttttttctg aaaaacacac tctgttccgt cccgtttctt tcgctttgta aagcatttga 985801 tcggcaagaa tgggcaagga tcctggctgt tccgtattat tggggtaatg agcggcccct 985861 agtgatatcg taactgaaag ctcgtcgccg tttgttaata caatcggtgc atcacttaca 985921 gtgctcctga tccgttcagc gatccgggct gctttatcaa gagaacagtt cggcaggagc 985981 acggcaaatt cttcaccgcc gatccgagcg gcaggatcag tatttcggat ggtctgcttc 986041 agacgtaacc ctagctcttt gagcacctga tctccttcat gatggccata ttggtcattg 986101 atggtcttaa aatgatcgat atccatataa atcagtgcaa attgaaaatg cggggtatcg 986161 gccgcctgct gatacagagc ttttgtggtt tcttcaaatt ttcttcggtt atacacgcct 986221 gttaaaaagt caaagtgcgc ctgaaactta tattgtttaa aaagaagatg tgcatttgtt 986281 tcatgatcaa taatatataa actgagcatg ccgcccgcta ttgatatgat ccaaaaatac 986341 aaatgaagtt cgtatgaatg taaatctata agaaaataaa aggaaaagga gatcaagcta 986401 tttgtgatta ttaaaagata gaaagcatgt tttagttgaa ctttttttct tctagaaaca 986461 atgagtgacg gaatggcagc gatacaaatg ataataaccg agtatagtgc agatgtgttc 986521 atcgtaatca gcaagcggcc tgcagtgatc atggccaggg ccgttgccgt tgaaacccag 986581 cctccataaa gagcggcaat cataataggg atatttcgaa gatcaataat tgaatgctga 986641 taggtaaatc caaaaaccat cagaataacc ccgagcaaac cgcaggccag tcctttaaca 986701 gcttgaaagg atatgctgtc ttttttatgt actagccttt ctttaaacag gtgggtgaag 986761 agataattaa atgtgattaa aatggtcaaa tttacaaaca gttctttcag caaatattat 986821 cacccttata taaggtacta aagatggaag ggaaagaaaa gaacaaaaaa ggcattatat 986881 aaggtttttt tacttgaatt gataagttaa aataattcgc acttgaccca tcggaattag 986941 tgtaatatag taaatgagaa aatttgaagg gagagtttac ctgctttgga gactttactg 987001 gttgtattac atgtatttat tttattttta cttatcttag ggctctttgt tatgcagaaa 987061 aaacatgttt ccttctctaa acgtgtattt actgcgctgg ggctggggat tgtattcgga 987121 tttgcgcttc agctgattta cggcccgact tcaaatatag tcattcaaac agccgactgg 987181 tttaatattg ccgggggcgg atatgtcaaa ttgcttcaga tggttgtcat gccgctcgtc 987241 tttatttcga ttctcggcgc ctttacaaag ctgaagctga caaaaaatct tgggaaaatc 987301 agcggtttga ttatcgggat tttagtagca acaacagcag ttgctgcagc tgtcggtatc 987361 gcgtccgcgc tttcatttga tctgcaggcg attcaggttg accaaggaag tacagagctt 987421 tcacggggac aggagcttca gcagaaatca gaggatatga cagcgaaaac gctgccgcag 987481 cagattgttg aactgctgcc tggaaacccg tttttagatt ttacgggagc tagaccgact 987541 tcaacgatcg ctgtcgttat ttttgccgct ttccttggag tggcattcct cggcgtaaaa 987601 cacaaacagc cggaacaggc agaaacattt aaaaaactgg ttgatgccgt ttatgccatt 987661 gtcatgcgtg ttgtcacact cattttgaga ctgacgcctt atggggtgct ggccatcatg 987721 acaaaaacaa ttgcaacgag tgatcttgac agcattctaa aactgggcat gttcgtgatt 987781 gcatcatatg ccgcgttaat cactatgttt atcattcatt tgctgctgct gacgttcagc 987841 ggcttgaatc cggtgattta tttgaaaaaa gcggtgcctg tacttgtatt tgcatttacg 987901 tcaaggtcta gcgcaggtgc tttaccgctg aatattaaaa cacagagaag catgggtgta 987961 ccggagggaa tcgcaaactt tgccggttcg ttcggtcttt cgatcggcca aaatggatgt 988021 gccggcattt atcctgcgat gctggcgatg atgattgctc cgactgtcgg ccaaaatcca 988081 tttgacccgg tgtttattat cactgttatc gcagtcgttg ccatcagctc cttcggggtt 988141 gccggagtcg gcggcggagc gacattcgcg gcgcttcttg ttttatcatc attaaacatg 988201 cctgtcgcgc tcgccggttt gttaatctca attgaaccgt taatcgacat ggggcgtact 988261 gctttgaatg tcagcggaag catgacatcc ggtcttatta caagtaaggt cacaaaagaa 988321 attgatcaag gggcatttca tgatcaatcc agagtgattg aagctgaaga agcgtaacat 988381 atgaaaacgt gtaatccaag aggattacac gtttttttaa cggccaggct ctaagtcctc 988441 cagcatttcc atcatcgtgt tgtcgtccat gacattcatt gcgttttgtt caaaatgaat 988501 gggttcagca taatgcggct gtcttttttt cgcggctgtc tcagtttgcc tagtttgaga 988561 ctgtgtatgc tgatgctgtg gttgctgctg tccagcgtgc tggtgctgac ggccattttg 988621 ccgctggctt tgatgctgcg aacggtcctg gttatcaccg ctgcttccgc tgcttccgct 988681 aaatgcttgt ttgaccatgt ttcctacatt agaagcatca aacgtgttat tttctgaatt 988741 tcgtctgttc atttgtcctg tgataaaccc gctgattctt tggcggatct gaggtgataa 988801 tgcagtaata agcatagttg atcctatgat caatgctgcg gggctgattc ctcttcgctg 988861 gttgaacaac atgatccctc ctttgcagtg tattcatatt ttccccctcg ttagacaaat 988921 taaccgttat atttcccggg aaagcatttc ctccagattt gcatgcataa ttaaagccag 988981 ttagaaaaac ctataagtaa agtgataaag gaggaattca catgtttgga aaaaaacaag 989041 tccttgcgtc tgtgcttctt atccctttgc ttatgactgg ctgcggtgta gccgaccaag 989101 gtgagggcag acgtgataat aatgatgtaa gaaacgtaaa ttatcgaaat ccggccaatg 989161 acgatatgcg gaatgtaaac aatcgggata acgttgacaa caatgttaat gataatgtca 989221 ataacaatcg tgtaaatgac gataataaca acgaccgaaa acttgaggtt gctgatgaag 989281 cagctgataa agtaacagac ctaaaagaag taaagcatgc cgatatcatt gtggctggaa 989341 atcaagccta cgttgcagtc gttttaacca atggaaataa aggtgcagta gaaaacaatc 989401 tgaagaaaaa aatagccaaa aaggtaagat ctactgacaa aaacattgat aatgtttacg 989461 tttcagctaa ccctgatttt gtagagcgta tgcaaggata tggaaagcgt attcaaaatg 989521 gtgacccaat cgccggatta tttgatgaat ttacacaaac tgtacagcgt gtattcccta 989581 acgctgaata aatgaaagaa gccgcacaat ttgtgcggct ttttctttgc gttaatgaca 989641 cactgcgaac tcaggctgca tagagtaaaa ataaaaaggt acaagacgga ccggctcagg 989701 gagggagacg tttgcgggat ggcataggaa agcgtgcggc atccgctcta ttcctgtgcg 989761 gagtccttgt gatgctggct gtaagctcag ccatcgtatc aagcgcgatg tatatcctgt 989821 cttttccagg tcaggcatct ggaataacaa aagaacaagt gacgaagcac atgaagaaag 989881 agtcattcaa acaggccgat atttattaca cttctaagga aaagtcctta ctgccattga 989941 cgaaagaaac gcttgaatat gcggtcagta ttaatcagat tatgattgga tattcgaatc 990001 aaaagcctat tgacattatt ttttttccta atgaaaaaca gatggaggct tactccggtt 990061 tattggatgt agttggtttt tattctgaac gggagcagct gatcggattg ttgcctgaag 990121 agaaaaagaa actgttagaa ggggacgagg tagcggttta tttgtaccag agattgttga 990181 ttcatgaata ctcgcaccat gcgtttcacc agaaattgaa ggagcttgag acggatcccg 990241 atgagtttcc gttatggttt catgaagggt taagcgagtg gattgcgaac tatgaattgc 990301 tcatagatcc gatcacgttt tctgtcgtgc cctttgaccg tttgcagact gatcgagact 990361 ggcaggaagc tagagccgaa tatgacactg atgtctattt gcaaagcttt tatatgatcg 990421 atgagctgac ggacaaatac gggaaagaca ttatttcaga aatgattaag gaaacggcaa 990481 aaaaagggga ctttgaaaaa gggtttaaat cagcaacaaa ggaaagtctt gatcaatttg 990541 aaaaagattt taagaaaaaa tttgaaaaaa acagtgcggc attggatagt atctatccaa 990601 tgcctttgtt attagtgaag tccttgctga cccattccgc cttgtgtcgg aggcatttgt 990661 ccttgggcag gggcgaatga atttcgcagc tgttccatat cctgcgcatc aagctgagga 990721 acctggtaat agccgtgttt gttttggtat aggaaaattt caaatgccat ttcaacatac 990781 tcctgaattt gcgcagacag tacgcgtctt acggccggat ttgtcatttc cagagaagcc 990841 atcgtcagca tagaagcttg tgctttaatc gcgcaaagca tttgtcggct gatgatgctg 990901 tcatcaatat cattcatgga ttgaacaggt tttttaggct gtgacggctg catgccgtaa 990961 acagtctggt tgtcttcctt catcatataa gttgctgttt tttgtgaagg ttcgcttcct 991021 gttttgaagc attctgcagt tatattgtat tgagatgtga tgaattgatg ttgacgatca 991081 aggatgttta gtaattcttg atccttacag aattgtctca gcatcataaa ctgatcaagc 991141 acagtaagtg ttccggaaag cacctcatgc atatcaaaca tttcatgtcc gccgtggttt 991201 ttatgcggtt tgccaggaat acctttgttc atttgggatt gctgctgctg attgaactga 991261 tccaaaccga attcctcctt ttttttcaga tcagctgtat tttgtgtcag tctgccgtgt 991321 attatgcaga agcctgaaag gaattatatg ctgtctgtcg aaatgataag cagacaaaat 991381 cgttgtcatt atgtgtataa gggaggaaat atgatgaggc gtattctgca tattgtgttg 991441 atcacggcat taatgttctt aaatgtaatg tacacgttcg aagctgtaaa ggcagctgaa 991501 ccgcaacagc ctatatcgat tgagaaggca atacagcaaa aagaaggaca ggcacttgtc 991561 gaaggatatg cagtcggcca ggctgtttcc ccgcagcatt ataaactgac aagccctttt 991621 tcaaatgatt ataatgttgc gctggcagac cgtaaaaaca aaacatcgcc cgaacacatc 991681 cttcctgtgc aaatcccctc cgccttcaga agccaatttg ggctgcaaac caatccgctt 991741 cttcttggga aaaagataac ggttcaagga aagcttgaaa attactttaa cacgacagga 991801 cttaaaaacg ttcagtcgat gaacgtaacc gatgacacaa aaactccgcc ggctgaacag 991861 caagtgacca taaatgaagc acggggaagg ctgaatgaag aagtaacgat aaaagggatc 991921 attacagctg atcaaaacgc aatcggaggc gggaagctgt cgaccttttt gcaagatgaa 991981 accggaggca ttaacattta ttcgccatcc cctgaacaat ttcccgaatt aaaagagggt 992041 atggatgtca cggtgacagg gaaaatcacg tcttaccagg ggctgaaaga aatcgttcca 992101 aactcatcag gcatcaaaat caaccagtca aatcaatccc tccccgcccc caaacactta 992161 acaatcaatg aacttattaa cggcagccta ggtgatcagt atgaaggacg ccttgtgaaa 992221 ctaaccgctt ttgtttcctc aattccaagt tctcctgccg gcggcggtta caatgtaaca 992281 atgattgatg acgaccatca tgcaatgacg ctccgggtta tgaatgaaac aggggtgata 992341 aacgagcttg atgagggcaa atggtatgaa tttaccggtg tgttaagcag ataccaaacc 992401 tttcagctgc ttccgcgaaa atcggctgac ctgaagctgc ttgaagagca gcccgcacct 992461 ccgtctgcag agggagaata tgaagggatt gttgaccggg tagttgacgg cgataccatt 992521 catcttaaat ctccggtgct tggaacgaca aaaatccggt ttgtaaatgt agatgcaccc 992581 gaaacatatc acacaccaaa aaatgacgca gatgaaaatc aattaagatt tggcaaaaaa 992641 gcatctgact atctaaaaac ggttctgtcc ccgggtgata aaattactgt caaggtcggg 992701 agtgaagcca aggacagcta tggcagattg ctcggacaag tcataaccga atcaggttca 992761 aacgtgaact tagagcttgt aaaaaacggc tatgctccga cgtattttat ttggccggtt 992821 gacaatgaag aggattatca gcaatttcag gccgcagtag ccgctgcaaa aaaagatcaa 992881 aaaggaattt ggaatgaaaa cgatcccctc atggaaatgc cgtttgaatt cagagccaga 992941 gagcaaggga aaggcctgac aagatatgtg ggggactcgt cgaataaaac atatgtgcag 993001 ccagctgact ggaagaagat agctgtggaa aacagaattt tcttcgcctc agcaagtgaa 993061 gcggagagcg cgggatataa aaaaaggcaa acggcacctc aagaacatgt gccgcttaga 993121 attctcagca tgaatgattt gcatggcaaa atcgatcagc aatatgagct tgatcttgat 993181 ggaaatggaa ctgtagacgg cacgtttgga cgcatggatt atgccgccgc atatttaaaa 993241 gaaaaaaagg ctgaaaagaa aaactcgctg attgtgcacg cgggagatat gatcggcgga 993301 agctctccag tttcctctct tcttcaggat gaaccgactg tagaactgat ggaggacatc 993361 ggatttgatg tcggaaccgt gggaaaccac gaatttgatg aaggcacgga tgaacttctg 993421 aggatcttaa atggcggtga tcatccgaaa ggcacaagcg gatatgatgg acagaacttt 993481 ccccttgtat gtgccaattg taaaatgaaa tcaactggag agcccttttt gccggcttac 993541 gacatcatta atgtggaggg cgtacccgtt gcttttatcg gagttgtcac acagtcggca 993601 gctggcatgg ttatgcctga aggaataaaa aatatcgagt ttacagatga agcaacagcg 993661 gtgaataagg cggccgaaga gctcaagaaa aaaggcgtga aggccatcgc ggttctcgca 993721 catatgtcag ctgaacaaaa cggcaacgcc attaccggtg agtctgctga tcttgcaaac 993781 aaaacagatt ctgaaattga cgtgattttt gccgcgcata atcatcaggt tgttaacggt 993841 gaagtgaatg gaaaactgat tgttcaagcg tttgaatatg gaaaagcgat aggtgtcgtt 993901 gatgtagaga tcgataaaac gacaaaagac attgtcaaaa agtccgcgga aatcgtatat 993961 gttgatcaaa gtaaaatcga accggatgtc agcgcgtcag ccattttaaa gaaatacgaa 994021 acaattgcgg aaccgattat cagcgaggta gtcggcgaag ccgctgttga tatggaaggg 994081 gggtattcaa atgacggcga tacacctctt ggaaacctga ttgcggatgg tatgagagct 994141 gccatgaaaa cggattttgc ccttatgaat ggcggcggca tacgtgaagc gctgaagaag 994201 ggtccaatta cgtggggaga tctttacaat attcagccgt ttggaaatgt gttaacgaag 994261 cttgagatta aaggaaaaga tttaagagag attatcaatg cgcaaatctc gccggttttt 994321 gggcctgact acagcatcag cgggtttacg tatacgtggg ataaagaaac cggaaaagca 994381 gttgatatga aaatggcaga tggcaccgag atccagcccg atgccacata tacattgacc 994441 gtcaacaact ttatggcgac ggcgacagga gccaaatatc agccaatcgg actgctggga 994501 aaaaatccgg tgacagggcc tgaggatttg gaagcgacag ttgagtacgt gaagagtttt 994561 gatgagccaa ttgcgtatac aaaagaggga agaattaagc ttgctgaagc cagtgatatt 994621 gaagaccctg taacagaaga cccgataacg gaagagcctg gagatgatcc ggggacggag 994681 gatccgatta aagaggatcc aaggccaggt gaagatttgc ctgatataaa agaaactccg 994741 ggaacagcac cggttcatca gcttccgcct tcagccattt cgagattcaa tgaaatacca 994801 atcaacaaca caaaaaccgc tgatactgct aatagcatca gcacattgcc gttacaaacc 994861 gagactgcgg aaagcgggtc tgatcatcag cttccggata cgtcagcggg ctactataac 994921 tttatggtaa tcggtgcggc ggtgacattg tcaggaactt atctatatgt cagaagaaaa 994981 aggagcgcct ccagaacgtg aaaaaagtta ttccactatt catcattgct gccggcctag 995041 tgatcgcagg ctatggaggc tttaaattga tcgatacgaa tacgaaaacg gaacagacat 995101 taaaagaagc aaagctggcg gctaaaaagc cgcaggaagc ttcggggacg aaaaatagca 995161 cagatcaagc aaagaacaaa gcatcattta agcctgagac cggccaagcg agcggcattt 995221 tagaaatacc gaaaatcaat gcagagcttc cgatcgtgga gggcaccgat gctgatgatt 995281 tagaaaaagg tgtcgggcat tacaaggaca gctattatcc tgatgaaaac ggacaaattg 995341 tgctgtcagg gcatcgggat accgtgtttc gccggacggg agagctggaa aagggggatc 995401 agctccgtct tctcctgtca tatggagaat tcacatatga aattgtaaaa acaaaaattg 995461 tcgataagga tgacacatct attatcacgc tccagcatga aaaggaagag ctgattctga 995521 cgacctgcta tccgttttca tacgtcggaa atgccccgaa gcgctatatt atatatggaa 995581 aacgagtgac ttaaaaagcc gaggcagtgc ctgcggcttt tcttcatgaa aaatatgtgc 995641 ggcaaaggtt tttcatatca gcagggaaag gggcttcagc aactatgagc tcgtctgtta 995701 tcgggtgaac cgcttgtact ttattggcgt gcagtgcctg cctgtttagc agcttgctcc 995761 cgcctccgta aagcgagtct cctgtcaacg gatggccgag gctcgccaga tgaacacgga 995821 tttggtgtgt tctgcctgtt tccagctcta attcaacgag cgacagccgt tctttcgcat 995881 tgctggccat taccttgaaa tgagtgacgg ctgtttgccc gcctggtgaa acccggcgtc 995941 ttgtcgggtg tgagcggtct ctgccgatcg gtgaattaat tgtccctttt ttcgtccgta 996001 gcttaccttc agcgatagcg gtatacgtac gcttcagcgt ctttttctct aactgctggt 996061 ctaagatggc gtgtgccaaa cgatgcttgg caaaaacgat agcgccagat gtatcctgat 996121 caagacgatg gacgtggcgc accttacatg tttcgccatt tatctgataa tgatacgcga 996181 tcaaattagc cagtgtgccg gtttgcccat cctcattcgg atgcgtcgcg atgccagcgg 996241 gtttattgat gatgagcata tgattgtcct caaataaaat atcaagctcg ccatactccg 996301 gaatgaccga agatgcttca ctttcctgaa gatcaatgaa cacgcggtct ccctttttta 996361 caatcatatt gtttaagacg gattcgtgat tgacctttat ctgttgatgg gacatccagt 996421 cttgtatcac tggtttagaa gctttgagcg ctgttttgag tacggaaaac agccattggc 996481 cgtcctgttt ttcattgatg aggatctcaa gccctctgcc tttttggttc atgttaaatg 996541 gctccttttc gaagcggaag gctgctgttt ctcataggaa acacttacct tagctttcgc 996601 gtttttttct gtgctattct tgagtaagac ttaggatatt cgatggcaag aaaggtgatt 996661 gacgtgagaa ttgtgaacgc agcaactgca gaacaggaga gctttatcaa ggagctgtct 996721 atggagctga tccatgatgt atttcctctt tatttctccg aactggacat tcagcgcttt 996781 aaaaagaaag gcgttctgtc tttaaataac cattattacc aaggaacatt aaaagaagca 996841 tttcaaatta tggcttgtct gcaaatgata catattatcc tgaccaagcc ttcgccgcac 996901 tctgatttga gtgatcaggc gatttttgaa aaaaacagca agatgctgaa tgattttggg 996961 atttattttc cgtttgcttt ttctgacttt caaaagaaga ctaacaaagc ctttttcggt 997021 caaagaaggc tgatataatc atgcggcaag ggcttttcta tttttagaaa agctcttttt 997081 gtatcagaga aatcatatca taaaaccttt cctctaactc cctttttaaa cggctcgtgt 997141 ctgaacatac taatgattga aaggggtgct gacaatgagt tcagttaaag atacaatgac 997201 aacgcaggtg gcaaccgttt ctccgaatca aacgattcag gaagcggctt ctctaatgaa 997261 acagcataac gtcggggcga tccccgttgt agagcaaggt gttttaaaag gaatgctgac 997321 tgaccgtgac attgcattaa gaactacagc tcagggccgt gatggccaga cacccgtttc 997381 agaagtgatg tcaacagaac tcgtatcagg aaaccctaat atgagtctgg aagacgcgtc 997441 gcagctgatg gcccagcacc aaatccgccg ccttcctatt gtagatcaaa acaatctagt 997501 cgggatcgtt gcgcttggag acctggcagt caatcagatg tcgaacgagt ctgcgggatc 997561 agcgctgaca aacatttctc accaaaacat tcattaataa gaaagagctt gcagtgtgca 997621 ggctctttct tcacataaaa ccttactttt tgaaagcaga cttgtttcgg ggtatagtga 997681 gtgtatacat atgtctcaat tcgtactaaa ggagttgtac ccagtgatta aagcgttaat 997741 ttttgatttt gacgggctta ttctagatac agaaacacac gaatatgagg ttcttcagga 997801 aatatttgaa gagcacggct cagtgctgcc gctatctgtc tggggaaagg tcatcggaac 997861 tgctgcgggt ttccggcctt ttgaatattt agaagagcag atcgggaaaa agctgaacca 997921 tgaagagctc acacaattga gaagagagcg gtttgccaaa cgcatggaat cagaaaaagc 997981 gagacctggt gtcgaagcgt atttgaatgc ggcaaaggat ttaggcttaa aaataggcct 998041 tgcctccagc tctgattata aatgggtgtc cggccatttg aagcaaatcg gcctgtttga 998101 tgattttgaa gttattcaaa cggcggatga tgtggaagag gtgaagccga atcctgaact 998161 ctatttattg gcggcaaaga acctgggggt atcgccagcg gaatgtctcg cgtttgagga 998221 ttctgtcaat ggttcgattg ctgcgaaacg tgcaggcatg aagtgtgtca ttgtcccgaa 998281 taaagtaacg ggtaccttga tgtttgaaga ctatgatcac aggcttgaat caatggcgga 998341 gatggagctc gccctattgc ttgatcatct gaactcacaa aactagaaag gagcgagtag 998401 gttgtctgag aaattagatt tgacccggtt tgaaaagaaa atggttatcc gcaatatcga 998461 agagaaagac atcgacaaga ttatcgatct tcaaaaggac tgctttccag gaatggagcc 998521 ttggaagcgg gagcatttaa tcagccattt ggagcatttt ccggaaggac agttttgtgc 998581 agaattcgaa ggtgaaatta tcggttcgtg ctcaagtctc ctgattaact ttgatgaata 998641 tgatgaccgc catacgtggc aggacattac agatgacggt tatatcacca accataatcc 998701 tgacggcttg aatatgtacg gaattgaagt catggtgcac ccgaaataca gacgaatgaa 998761 gatcggccac cgtttgtacg aggcgagaaa ggacttagcc agacgcttaa acctgaaaag 998821 catcatcata ggcggacgga ttccaaacta tcacaaatat gcagaggaaa tgacagcgag 998881 agagtatgtt gaacaggtga cacgccacca aatttacgat ccggttcttt cttttcagct 998941 gatgaacggc tttaccctta tgcgaattaa cccgaactat ctcccggatg atacagcttc 999001 gatcaagtat gcgacgctga tggaatggaa taatgtcgat tatctaccgc agcagacaaa 999061 acgctattat aaatcggcgt tccctgttag aatttgtgtg atccaatacg aaatgaagaa 999121 aatttattcc tttgaggaat ttgcgaatca agtagaatac tatgtcgatg ttgcttccga 999181 cgcaagatct gattttgcgg tgttcccgga aattttcaca acccagctga tgtccttcct 999241 tgaggaacgg tcaccgagct tggcggtgca gagaattacc gagtatacag aagattacat 999301 cagcctgttt actgacttgg ctgtgaagta taacgtcaac attatcggcg gatctcattt 999361 cgtcgaagag gaaggcaaga tctataatat cgcttacctg ttcagacggg acggaacgat 999421 cgagaagcaa tacaaactcc atattacgcc gaatgaacgc aaatggtggg ggatcagcgc 999481 aggagaccaa gttcgcgtgt ttgatacgga ctgcgggaaa atcgcgatcc agatctgtta 999541 tgacattgaa tttcctgagc ttgcccggat tgcggctgat aaaggagcca aaatcatctt 999601 tacgccattt tgtacagaag accgtcaagg ctatctgcgt gtcagatact gttcgcaggc 999661 tagagcggtt gaaaatcaaa tttatacggt tatctctgga acggtcggaa accttccgca 999721 aacggaaaac atggatatcc aatacgccca gtcaggcatc tttgccccgt ctgattttga 999781 attcgcccga gacggcattg tcggcgaaac aaacccgaat attgaaatgg tcgtcatcgg 999841 cgatgttgac ctggaaattc tcagaagaca gcgccaaaac ggtacagtgc gccagctaaa 999901 agacagacga cgtgatattt atcatattca atataaaaaa taattcccaa aaaacccgcc 999961 tgaattggcg ggttttttta aacaaaagcg gaattgttta ggtgctttct ttaaaataaa 1000021 agtaaattgt atagtggatg tgccttatgg agtttctgta ttttcgccat ttcctatatc 1000081 atacagaaaa cggctaggct tcacattgct attgcaatgg ctgtccaagt tgtttcgagt 1000141 gcgaccttta tcagtacgat gctgagcatt gtcactttgc ctgttttgct ttggaagctg 1000201 catcctcttt cttcttgaga aaggggatgt tttattattt acgcggttta ttgactctga 1000261 cccggtctgg ctttatattg aaggcaggga aatcatcacc aagacatcac ataaagagaa 1000321 ggtctgtttc aattgaattg gcattatagg gaacgctaat gaaatggaga tgatggggat 1000381 ggaaaacatt cagcaaaatc agggattaaa gcaaaaagat gagcaatttg tgtggcatgc 1000441 catgaaggga gcgcatcaag cggacagcct gatagcccag aaggccgaag gggcctgggt 1000501 aaccgacaca gacggacgcc gctatttgga tgcgatgtcc ggtttgtggt gcgtcaacat 1000561 tggttacggc agaaaggagc ttgcggaggc tgcctatgag caactaaagg agctgcctta 1000621 ctacccgtta acgcaaagtc acgcacccgc aattcaactg gcggaaaagc tgaatgaatg 1000681 gcttggcggc gattatgtta tttttttttc caacagcgga tcggaagcaa acgaaactgc 1000741 ttttaaaatt gcccgccagt accatctgca aaacggcgac cacagccgtt ataaattcat 1000801 ctcaagatat cgggcatacc acggcaatac attgggagcg ctctcagcta ccggacaggc 1000861 gcagcggaaa tataaatacg agcctttgag ccaagggttc ctgcatgcag ctccgccaga 1000921 tatataccgg aatcctgatg atgcagacac gcttgaaagc gcaaatgaaa tcgaccgcat 1000981 catgacatgg gaattaagcg aaacgattgc cggggtcatt atggagccca tcattacagg 1001041 cggaggcatc ctaatgccgc cggacggata tatgaagaag gtggaggaca tttgccggcg 1001101 ccacggagcc cttttgattt gcgatgaagt gatctgcggg tttggacgga caggtgagcc 1001161 gttcgggttt atgcactacg gtgtgaagcc tgatatcatt acgatggcaa agggaatcac 1001221 aagcgcgtat ctgccattgt cagcgactgc tgtgaaacgg gacattttcg aagcgtatca 1001281 gggggaagct ccttatgacc gtttccgcca cgtgaacacg ttcggcggaa gcccggctgc 1001341 ctgtgctttg gcgttgaaaa acctgcaaat tatggaggac gaacagctga ttcagcgatc 1001401 ccgtgatctt ggagcaaagc ttttaggtga gcttcaagct ctgagagaac acccggcagt 1001461 cggggatgtt agaggaaaag ggctgctgat cggaatcgaa ctcgtcaaag acaaattgac 1001521 taaagagccg gctgatgccg ccaaagtaaa ccaagtggtt gcggcgtgca aagaaaaagg 1001581 gctgatcatc ggcaaaaacg gcgatacagt cgccggctac aacaatgtca tccagcttgc 1001641 gccgccattt tgcctgacag aagaggacct ttcctttatc gtgaaaacgg tgaaagaaag 1001701 ctttcaaacg atataatata aaagtgaatt attaaaggag cacatgatga gttttcacaa 1001761 ccagccgatc ttaccggcta ttcgcaatat gaagcaattt gatgagtttt tgaacagttc 1001821 attctcttac ggtgttattc ttgatattca tctcggccag ctgaagggcg tgatcaaaga 1001881 agcgcaaaag cacggaaaga acatgatggt gcacgtcgat ctcattcaag ggattaagca 1001941 tgacgaatac ggtgcggaat ttatatgtca ggatatcaag cccgctggga ttatttccac 1002001 aagatcgaat gtgattgcca aagcgaagca gaagaaaatt tatgccattc agcgcctgtt 1002061 tttgcttgat acaagcgcga tggagaaaag catggagttt atcggcaagc ataagcctga 1002121 cttcatcgaa gtgcttcccg gcatcgttcc gtcactcatt caggaaataa aagagaaaac 1002181 agggattccc atctttgccg ggggtttcat ccgtacggaa gaggatgtag agcaggcatt 1002241 gaaagcgggg gctgtagctg tcacaacatc taataccaaa ttgtggaaaa aatatgaaaa 1002301 ctttttgacg gaaagtgatt gacaccgctt tcatgcactg atacaattgc actaggttaa 1002361 tacattgtga tggagaactc ggagaccaca gcagctcttt acggcaaatg tttatgcacc 1002421 cgtaaagcgg tttgttgtgg tttttttatt ctcttcttct ctatcatgct ttttaatcgt 1002481 gactttagga ggaatgtgct atgacagcat tttggggaga agtcatcggt acgatgctgc 1002541 ttatcatttt tggtgcaggt gtttgtgcag gtgtcaattt aaagaaatcg ctttcattcc 1002601 agtctggctg gattgttgtt gtatttggat ggggattggg tgttgccatg gcggcatacg 1002661 cggttggcgg catcagcggt gcccatttga atccggcgct aacgatagcg cttgcatttg 1002721 taggagattt tccttggaaa gaggttccgg tttatattgc ggcgcaaatg atcggagcga 1002781 tcatcggtgc ggtgattatt tatctgcatt acctcccgca ctggaagtca acggatgatc 1002841 ccgctgccaa gctgggtgtt ttctcaacag ggcccagcat tccgcataca tttgcaaacg 1002901 ttttaagcga agtgattggg acatttgtcc ttgtacttgg aatcttggcc ataggtgcaa 1002961 atcaatttac agaaggactt aatcctttaa tcgtcggttt cctcattgta gcaatcggta 1003021 tttctctggg aggcaccacc ggctatgcta tcaatcctgc acgtgactta ggtccgcgga 1003081 tcgcccacgc ttttcttccg attccgggga agggctcatc aaactggaaa tacgcatggg 1003141 ttccggtagt cggcccgatt ttaggcggat cattcggcgg tgtattttac aacgctgcat 1003201 ttaaagggca catcacaagc agcttctgga ttgtaagcgt tatattggtt gtggtattgt 1003261 taggactcta tgtttatacg aaatcacatt ctgctaaaac attatcaaat tctaaatata 1003321 tttaatcaaa ggggagacat cttatggaaa cgtacatttt atccttagat caggggacga 1003381 caagttcaag agcgattctg tttaataaag aaggcaaaat tgtccactct gctcaaaagg 1003441 aatttacaca atacttcccg catcctggct gggttgagca taatgccaat gaaatttggg 1003501 gctctgtcct cgcggttatc gcctcagtca tctctgaatc aggaatcagc gcttctcaaa 1003561 ttgccggcat cggcatcacg aaccagcgcg agacgacggt tgtgtgggat aaagatacag 1003621 gaagtcctgt ctataatgca atcgtttggc agtccagaca gacgtccggc atttgtgagg 1003681 aacttcgtga aaaaggatat aatgataaat tcagagaaaa aacagggctt ttaatcgatc 1003741 cttacttctc cggcacgaag gtgaagtgga ttttagacaa tgtggaaggc gcaagagaaa 1003801 aagcggaaaa aggcgagctg ctgtttggaa cgattgatac gtggctcatt tggaaaatgt 1003861 caggcggaaa agcgcatgtg accgattact ccaatgcctc aagaacactg atgtttaata 1003921 tttacgattt aaaatgggac gatgaactgc tcgacattct aggcgtaccg aaatccatgc 1003981 tccctgaagt gaagccgtcc tctcatgtgt atgcggagac tgttgattat cacttcttcg 1004041 gaaaaaatat cccgattgct ggagcggcag gcgaccagca gtccgcattg ttcggccagg 1004101 catgctttga agaaggcatg gggaaaaaca cttacggcac aggatgtttc atgctgatga 1004161 ataccgggga aaaagcaatt aagtccgaac atgggctttt gacaacaatc gcttggggca 1004221 ttgacggaaa agtgaactat gcgttagaag ggagcatttt tgtcgcaggc tctgccatcc 1004281 agtggcttag agacggtttg agaatgttcc aggattcatc gctaagcgaa tcttatgcag 1004341 aaaaagtgga ttcaactgac ggcgtgtatg ttgttccagc atttgtcgga ctgggaacgc 1004401 cttactggga cagcgatgtg cgcggttcgg ttttcggcct gacaagaggg acaacaaaag 1004461 agcactttat ccgtgcgaca ctggagtcat tggcttatca gaccaaagat gtgcttgacg 1004521 caatggaagc agattcaaac atttcattaa agacgctccg tgtagacgga ggagctgtaa 1004581 aaaacaattt cctaatgcag ttccaaggag acctgttgaa tgttcctgtg gagcgcccgg 1004641 aaattaatga aacgactgca cttggcgcgg cttatttggc gggtatcgct gtgggattct 1004701 ggaaggaccg ttctgaaatc gcgaaccagt ggaatctgga taaacggttt gagcctgaat 1004761 tggaagaaga aaaacgaaat gagctgtata aaggctggca aaaagccgtg aaagcagcta 1004821 tggcttttaa ataaagtaat actatggtat aatggttaca agttaataag aacggtcctg 1004881 agatgaggag agaccacagc accaaagtgt aagcatgcac tttggctgtt gtggtctctt 1004941 tttctattta ccgtgacaac aaggaggaaa cgtaatgatg aatcatcaat tttcaagtct 1005001 tgaaagagat cgcatgctga cagacatgac gaaaaaaaca tatgacctat ttattatcgg 1005061 aggaggaatt acaggagccg gaacagctct tgacgcggca tcaaggggaa tgaaggtcgc 1005121 actaagcgaa atgcaggact ttgcggcggg aacatcaagc cgatcaacga agctggtaca 1005181 tggcggcttg cgctatttaa aacaatttga agtgaaaatg gtcgctgagg taggaaaaga 1005241 gcgggcgatt gtgtatgaaa acggcccgca tgtcactaca ccggaatgga tgctgcttcc 1005301 gtttcataaa ggcggcacat tcggttcatt tacaacatct attgggttaa gggtttatga 1005361 cttccttgca ggtgtgaaaa agtcagaacg aagaagcatg ctttcagcaa aagaaacgct 1005421 gcaaaaagag cctttggtga aaaaagacgg cttaaaaggc ggcgggtact atgtggaata 1005481 ccgcactgac gatgcgagac tgaccatcga agtcatgaag gaagcggtta aattcggggc 1005541 agagcctgtg aattactcca aagtgaagga gcttctttac gaaaaaggca aagccgtcgg 1005601 cgtattaatt gaagatgtgc tgacaaagaa agaatataaa gtgtatgcga aaaaaattgt 1005661 caatgctaca ggcccttggg tcgatcagct cagagaaaaa gaccattcga aaaacggaaa 1005721 gcatttgcag catacaaaag gcattcacct tgtatttgac cagtctgtct ttccgctgaa 1005781 acaggctgta tatttcgata cacctgatgg ccggatggta tttgcgattc ctcgtgaagg 1005841 caaaacatac gtgggaacaa cagacactgt ttacaaagag gcgctggagc atccgcggat 1005901 gacaacggag gatcgtgatt atgtcatcaa atcaatcaat tacatgttcc cggaactgaa 1005961 tatcactgcg aatgacatcg aatccagctg ggcggggctg cgtccgctga ttcatgaaga 1006021 aggcaaagat ccttctgaaa tttcacggaa agacgagatt tggacatctg actcaggcct 1006081 gatcaccatt gccggcggaa aactgactgg atacagaaaa atggcggagc acatcgttga 1006141 tcttgtccgt gatcgcttaa aagaagaggg cgaaaaggat tttggaccat gtaaaacgaa 1006201 aaacatgcca atctctggcg ggcacgtcgg cggttcgaaa aatcttatgt ccttcgttac 1006261 cgcgaaaaca aaagaaggaa ttgcagccgg tttatcagaa aaagacgcaa aacagcttgc 1006321 gatcagatac ggctctaacg tagatcgcgt ctttgaccgg gtagaagcgc tgaaagatga 1006381 ggccgcgaaa cgcaacattc cggttcatat tcttgctgag gcagaataca gtatagaaga 1006441 agagatgact gcaacccctg ctgacttctt tgtccgcaga acgggacgtt tattttttga 1006501 tatcaattgg gtaagaacat ataaagatgc cgttattgat tttatgagcg agcgattcca 1006561 atgggatgag caggcgaaaa acaaacatac agaaaacctc aacaagcttt tacacgatgc 1006621 ggtcgtaccg cttgagcaat aaatcataac gggctgtctg cagcccgtta tttcttttta 1006681 cgtgccgaaa gggggagatc tcaggttatc aagtgacaga ggcacccgct tcatataaaa 1006741 taatggcata agctgataca taggaggacg aatatgactt ggagaaagag ctatgaacgc 1006801 tggaaacaga cagaacattt agatctggaa ttaaaagagc gccttattga attagaggga 1006861 gatgaacagg cccttgagga ctgtttctat aaagaccttg aattcggtac cggcggaatg 1006921 cgcggggaaa tcggcgccgg gacaaatcgg atgaatattt acactgtgcg caaagcatcg 1006981 gccgggtttg cggcatacat ctcgaagcaa ggtgaggaag cgaaaaaacg gggcgttgtc 1007041 attgcttatg attcccgcca taagtctccg gagttcgcga tggaagcggc aaaaacactt 1007101 gcgacacaag gcatccaaac atacgtgttt gatgagcttc gcccgacgcc agagctgtca 1007161 ttcgctgtta gacagctgaa cgcttatggt ggaattgtgg taacggcaag ccataacccg 1007221 cctgaatata acggctacaa agtatacggg gatgatggcg gccagctgcc tccaaaggaa 1007281 gcggacatcg tcattgagca ggtaaacgcg attgaaaatg agctgacgat cacagtggac 1007341 gaagaaaata agttaaaaga aaaaggctta atcaaaatca tcggtgaaga tattgataaa 1007401 gtttatacag aaaaactgac gtccatttct gtacatcctg aattatcgga agaagtagat 1007461 gtaaaggttg ttttcacacc gctgcatgga actgcaaata aaccggtcag acgcggtctt 1007521 gaagcactcg gctacaaaaa tgtaacggtt gtcaaagaac aggaactgcc ggattcaaac 1007581 ttctccactg ttacatcgcc gaacccggaa gagcatgcgg cattcgaata tgccattaag 1007641 cttggggagg agcagaatgc agatattctc atcgcgacag atcctgatgc tgaccgcctc 1007701 ggcatcgcgg tgaaaaacga tcaaggcaaa tatacagtgc tgacaggaaa ccaaaccgga 1007761 gcgttgctgc ttcattacct gctttctgaa aagaaaaaac aaggcatcct gcctgataac 1007821 ggtgttgttc tcaaaacgat cgtcacaagc gaaatcggcc gtgctgtagc ttcttcattc 1007881 ggccttgata cgattgatac gctgacaggc tttaagttta tcggtgaaaa gattaaggaa 1007941 tacgaagcat caggccagta taccttccaa ttcggttatg aagagagcta cggttattta 1008001 atcggggatt ttgcccgcga taaggacgcc attcaggctg cgcttttggc agttgaagtt 1008061 tgcgcgttct ataaaaaaca gggaatgtca ttgtatgagg cgctcatcaa tctctttaac 1008121 gaatatggtt tttatcgtga agggctgaaa tccctgacgc tgaaaggcaa acaaggagca 1008181 gagcaaattg aagcgattct tgcttccttc agacaaaatc cgccgcagaa aatggcgggc 1008241 aaacaggttg tcacagcaga agattacgct gtaagcaaac ggacgcttct gactgaaagc 1008301 aaagaagaag ccatcgactt gccaaaatca aatgtattga aatacttcct ggaagacggg 1008361 tcttggttct gtctccgtcc ttctggaact gagccgaagg ttaaatttta tttcgccgta 1008421 aaagggtcat ctttggaaga cagtgaaaag cgacttgccg tcctttctga agatgtaatg 1008481 aagacggtgg atgaaattgt tgagtcaaca gcaaaataat tcaagtatga gctgggtcat 1008541 tgtaaatgat ccggcttttt ctttttctca tccaaaagtc tgaaagaaaa tcatcctaca 1008601 agtgaagcaa tgaaatacaa aaaactggta taatcttaaa tacaagatca atgccggagt 1008661 gagaaacgtg agcaaaacga ggatggaaaa attaaaaacg ctgaaaacga ttgcggaaac 1008721 cttaaatcaa gggcacgata tcaaagcaac actggatgag gttttaaaag agttgctgag 1008781 tctgacaaac cttcaatccg gatggatttt tctgatcgaa gaagatgggt cttatacgtt 1008841 agcggccgac gcttatctgc ccccggcttt aagccgcaag gaaaaagtgc tgatgtgcga 1008901 aggggagtgt tactgcctga cgaaattcaa taacggaggg cttagaaaag ctgcaaatat 1008961 catgaactgc aaacgcatcg aatcagcaga aaacctgcat tgttttgaca cagaagggat 1009021 tacgcatcat gcaactgtgc ctttagaaga cggggacaga agattcggat tgttaaatgt 1009081 agcggcggcc ggaaaaacca tgtttgatga ggaagagctg catttactcg agtctgtcgc 1009141 ctttcagatc ggaacggcaa tccagcgtat gaggctttct gaatatcaac aaaaaaatgc 1009201 tcttttaatg gagcgtaacc gcctcgctca ggagcttcac gattcagtca atcaaatgct 1009261 gttttccgtc agtttaactg ccaaagctgc gaagacacta acaaaagatg aaaatttaca 1009321 gcagatgatt gatttcatcc aaaacctatc acaggacgcg ctcgcagaaa tgaaagcgtt 1009381 aatttggcag cttcgccccg gaggattgga aaaagggctg gctgaagcca ttaaaagcta 1009441 tggtgcgctc attggattga agatcatttt tacacaaaaa ggctgtcctg ttctgactga 1009501 tgagcaggag catatgctat ggcgtgtcgt acaggaagct ttaaataact gcaaaaagca 1009561 tgccggaacg gatacggcgt atgttagtct gactgcttct ttgtgccatg cggagctgga 1009621 tatcatcgat catggggcag gatttcgcta tgaagcgcat gccggtctgc cttcacttgg 1009681 cataaaaggt atgaaagagc gagcggaaaa agccggagct aagttttgga ttgagtcagc 1009741 gcttggaact ggaacaaagc tgtccatcag gcttccgcta aaaagccgaa aaggaggggc 1009801 ggtatgaaaa ttgtcattgc tgatgatcat catgttgtca gaaagggtct gcgttttttc 1009861 tttgccaccc aggatgatat tgaagtcgtc ggagaagctg caactggatt agaagccctc 1009921 cgtgtcatcg aagagacaaa gccggatctt gtgctaatgg atttgtctat gcccgagatg 1009981 gacggcattc aagccattaa aaaagcaata cagcaatttc cggatacgaa tatcattgtg 1010041 ctgacgagct actctgatca ggagcacgtc atccccgcgc ttcaggcagg cgcgaaggcg 1010101 tatcaattaa aggatacgga gcccgaggaa ttggtgaaaa cacgacaagt gcatggtggc 1010161 gaatacaagc tttctacagc tattatgccc catgtgctga cacatatgaa aaatcagcac 1010221 gacccggaaa aagaaaaata ctatcaatta actagaaggg aaaaagacgt tctgactgaa 1010281 atagcgaacg ggaaaagcaa taaagaaatc gcagcagcct tgtttatttc agaaaaaaca 1010341 gtaaaaaccc atgtatcgaa tcttttagca aaacttgaag tggccgatcg cacgcaagca 1010401 gcgcttttcg cagtgaaata taacctgaat ggagagatct caaaatgaac atgttagtca 1010461 taaatggcac gccaagaaaa catggcagaa caagaattgc agcatcctat attgcagctc 1010521 tgtatcacac ggatttgatt gatctaagcg agtttgtatt gcccgttttt aacggtgaag 1010581 cggaacaatc tgaactgttg aaagtacagg agcttaagca acgcgttacg aaagcggatg 1010641 cgattgtatt attatcgcct gaatatcaca gcggcatgag cggcgcttta aaaaatgcct 1010701 tggattttct aagcagcgaa caattcaaat ataagcccgt tgcattattg gcagtagcgg 1010761 gaggcggaaa aggcggcatc aatgcgctga acaatatgag aactgtgatg cggggtgtct 1010821 acgccaatgt cattccgaag cagctggtgc ttgatccggt gcatattgat gttgaaaatg 1010881 ctacagtggc tgaaaacatt aaggaaagca taaaagagct tgtcgaagaa ctcagcatgt 1010941 tcgcaaaagc aggaaatccc ggcgtctaaa cgccgggatt tgtttatgtg agaagggcta 1011001 tttgatcttc ataagtcagc tctgtggcat gatcaatata tcggagaagg gaatacagca 1011061 tcttttctaa aacggcgtaa tcctgttcaa aatgatacgc atgcagaaaa tgctcaattc 1011121 gttttgataa caaatcgtcc tctgtacgca ccattaaaat taataaatta tcccattgag 1011181 aacgatgggt gtaataaagc gctttatcgt aatcggcata atccatgaat cgcttctcct 1011241 ttcttgggtg agaagttcat gattagttta tgccgcatcc tctgttattg acggggcaaa 1011301 acttgccgtc tgcgtcagta aaggggtagc aatatgaggg agacataaaa tcaaaatgcc 1011361 tgaatgaaga tatcgctttt ggtaaaccta tgagggaata tattctgggt acaggagact 1011421 gaaaaaatga aatccctgcc gtataccatc gcacttcttt tttgcggatt gattatcgtg 1011481 tcaatggctg caaaaggtca ttcaacggac acagacgagt ccgttcaaaa gtgggaacag 1011541 cttgcctgga gcaaaattca ggatgaatat aagggcgctt cattttctga ttatgcttat 1011601 atggggcgta cagaggtgaa tgatcagcag actaaagatg tctttcgggt gacagtcaga 1011661 cagaaagatg acactttttc tgttcgggcc gaagtctatt ttcatccggt gacaaatcat 1011721 atgatcagca tcaacgtctt taggctctaa taaaaaactg tacagccgtt aaggccgcac 1011781 agtttctgtt tttagaaata tcgttttgca ccgagatagc gctgtttcca gtaagagttg 1011841 ttcatattgg aaatgacaac tccggaatcg ttggcattta tgaattcccc gttgcctagg 1011901 taaattccga cgtgggaagg gccggcttta tatgttgaaa agaaaacgaa atctccgaca 1011961 gcaggctggc taactgattt cattgtgttc caatatcccg ctgccgttaa tctagatacg 1012021 gatgtgactt tgttcagtac atagtaaatg aatccgctgc agtcaaaccc ggacggtgtc 1012081 gtgcctcccc agcgatacgg aaccccaagc tgcgctttag cggccgaaat cattgtgtta 1012141 atcttcgcac tcgttgagct ggtggtgttt gaagaaccgg atgaagacga tgatgaagct 1012201 tttccggaaa tgaccagctt ttggccaacc tgcaagacat ccgtttttaa attgtttttc 1012261 tcacgaatct gctgagctgt tacattaaat ttttgagcaa tcacccataa ggaatcaccg 1012321 cttttcaccg tgtatgtagt cgtcgtgccg gagcttgcat ttgacgaaga agacgacgat 1012381 gatgaagagc ctgaagatgc tttacctgtc agcttcaata cttgtccaac gtaaagcaca 1012441 tctgatttca gattgttgat atttcggatt tgctgtacag tcaggttata gttgtttgcg 1012501 attttccaaa gtgaatcacc gcttttaacg gtatatttag ttgttgctga agtttggttc 1012561 gatttggatg aattgtcttt agaagacgta tcagagccgc ttgattttgt tttcaacacc 1012621 tgattcacgt aaatggtgtc tgattttaag ttgttcaaga ccttcaattc agcgatggac 1012681 atattgactt tgtttgcaat tttccaaagt gaatctccaa gctgcacctt atatgttccc 1012741 gtagaagatg aagaacttga actcttatta gaactgcttt ttgaactgga gcttgaactc 1012801 ttattagagt tgcttttttt actggaacta gagcttgaag aaacagtacc ggacaccttt 1012861 aatttctgcc cagcacgaat taaatcgctg cttagtccgt ttaatttttt cagttcctgc 1012921 accgtcattt taaactcatt tgcgatcagc caaagtgaat ctccgctttt cactgtgtaa 1012981 acagaacttc cgctcttctt ggttgttgag cttgaagtag atgaagaagt gctggatttg 1013041 ctgcctggaa tagtaagcgt ctggccgatc gacagaacag tagtcgaaag atgattggcg 1013101 gatgtgaggg ccgccacact tgtgttatag gtttgggcca gtttccataa agaatctccg 1013161 cttttgacct taatcgttgc tgcttcagct ggtgtcacta ctaaagttgt gccgacaatc 1013221 gcagatgctg tcagccctgc tgctaatttc tttttcatct tagctctcct ttttccccca 1013281 atgattttgc atttgctgtt tcttttttat atcggcacat ttgtctcatc gttttgcctt 1013341 tttataaaaa tagccaaatt atcttaacaa taagggggaa aaagggcata aaaaaagaag 1013401 gaatcttaat ctattccttc atttttaaaa gcttcatgat atcttctttg tttttgacga 1013461 ggtcgcgcag tgtgtatttg tctaaaactg cgaggtaggc taaaagcgct tcattcagca 1013521 catgttttaa gccgcaaacc ggggaaataa cacagagatt cttgttcgca tcaaaacatt 1013581 caacaatatt aaaatcgtcc tccgtttttc tgacaacctc accgatgttg atgtcttcag 1013641 ggtccatgcc taatcgtatg ccgccgcccc gtccgcgtat cgtttctacg tagccgagct 1013701 ggccgagcct gtatatgact ttcatgagat gattttttga aatagaatac gtttcggcaa 1013761 tctgttttat atttgaaagt tctccgggac gctctgcagc cagaaaaatc aacactctta 1013821 atgaataatc tgtataattg gttaacttca taataagacc tcagaataag acattttcta 1013881 tatcttatca taatcgattg aaaaatgaaa aaaaaggaat taaaaaacat gcacccagct 1013941 gggtgcatgt tttttgctta catgtcattc ggcggatttt ggtttttacg gtttttttcg 1014001 atttctgtgt tttgcatttt gcgttcaaat gtagacagat aacgtgatgc aaaatcctta 1014061 ccgccaaggc cgaaggataa accaaaagca agtgcgaagc cgctaagaac gatgatgaac 1014121 gcggaattga cgattgtcgc agcgacaccc agctgatcca gggccataaa gaaagcaagt 1014181 gcgataatcg tatatttagc aataggcgct aaagacttga attcctgacc ttttatcatg 1014241 cttgcgagca cttttctcac caattctcct gcgtaaaggc cgagtccgag aatgaatact 1014301 gcgacaagga cattcggcag atacgcgatg atgccggtgg caatttctac gaggaagtgc 1014361 agccgaacaa tttgaagcgc ctcagctgta aagagcagaa tgacaatgat ttgcgcaatc 1014421 ataccgacaa cttgagacaa ggacagcttt gcaggcgttc cggcttccat gcccattttc 1014481 cctaagacag aatcaaagcc tgcgcgatgg agcagtccgg acaccatgga tttcacccat 1014541 tttcctgccc agatacccgc taatacaagc acgatggcaa tcatgatgtt cggaagcatg 1014601 tttaaaatcg tattcagcat agagacagct ggttttgaaa tgccggcgac atccagctga 1014661 tcaagcgctg aaatgaccac cggaatcata atgagcacat aagcgattgt tccgatgact 1014721 gctgaaaggc ttgtgtcttt taagtaaatt gataaaccca tacgtgccgc gaatctttcg 1014781 gtgccgatgc ttgcaaggaa attcgtaatg atatcacgga caaggcgggc aacaagccat 1014841 ccgattaata cgataagcgc cgctgcaaat aatttcggca gaaaagcgag cacgctttcc 1014901 atcatatttg taaaaggacc tgaaatgccg ctgattttca aagaagataa gacccctggc 1014961 agaaaaacaa gcagcacgag ataaaagaca atttgtgaag cggtattgac agcctggtga 1015021 atatcttttc cttcagacac caaattccac ttgcgcagtt tgtcactcgt gttcagcttc 1015081 atcccgattt ttttgacaag gaagctcaaa acagaagctg cagcccatcc taacagcaga 1015141 atgagtccgg ctttcagcac gcttgggatc gcagctgcaa tcgccgaaag catactgaca 1015201 aacggcgatg ccactgttgt caggtgcaaa atgttaaaga ataaaataaa gacgatgatc 1015261 agtgcgataa aataaacgac cttgcttatg actttttccg aggaatagcg tgaaggcttt 1015321 ttcccagcaa agagcttgtc gtcgattttt gttttgctga gtcctttgta taccgctttt 1015381 tcaatgattt tagcaatagc ccagccgatt aataagacga gtaaagcaat gattacgttt 1015441 ggcagcttac tgagataaga agaaaacacg tctgctacat tcaattggta tcgctccttt 1015501 ttcgtagtat ggtgtgtgtt tacccactta tccaataagc aaacagatga atgtgccggg 1015561 ggaatttttt cttgcccgag tgagactatc atcttttgtc tggcgggctc atacattata 1015621 gataagtcca agtagggggg attcggttga acgcggagga gaagaaggga ttacagcggg 1015681 caattgagga aattaccgaa attgcaaaag gattcggcct tgatttctac ccgatgagat 1015741 atgaaatctg cccggctgaa attatttata catttggcgc gtacgggatg ccgacaagat 1015801 tcagccactg gagcttcggc aagcagtttc acaagatgaa gctgcactat gatctagggt 1015861 taagtaagat ctatgagctg gtcattaact cagatccatg ctacgctttt ttgctggaca 1015921 gcaactcact gatccaaaat aaattgattg tcgcacacgt tcttgctcat tgcgatttct 1015981 tcaaaaacaa ctgccgtttc caaaacacga agcgcgatat ggtggaaagc atggcggcaa 1016041 cagctgaacg gataaaacac tatgaacagg ttcacgggat aaaagaagtc gaatcttttt 1016101 tagatgcaat cctttcgatt caggagcata tcgatccgtc gttggtccga ccaaagctcc 1016161 aatggagtgt ggatgatgag gaagaggaga ttgaagaggc agccacgcct tacgatgatc 1016221 tatggtcttt agatgaaaag aaaccgaaaa aacaagtgaa aaaatcgaaa aaaccgttcc 1016281 cgccgcggcc tgaaaaagat atcctgcttt ttatcgagga gcattcccgg gagctggagc 1016341 catggcagcg tgatatatta acgatgatga gagaggaaat gctttatttc tggcctcagc 1016401 tggaaaccaa gattatgaat gagggctggg cttcctattg gcaccagaga attatacgtg 1016461 agcttgattt aacctctgat gaagcgatcg agttcgccaa gctgaatgca ggtgtcgttc 1016521 agccgtccaa aacaggcatt aatccttatt atttagggct gaaaatattt gaagacattg 1016581 aaaagaggta caacaacccg acggaggaaa tgaagaaaat gggcgtgcag cctgactccg 1016641 gccgggagaa aatgtttgag gtcagggaga ttgaatccga tatctctttc atccgcaatt 1016701 atttaaccaa agaattagtc atgcgcgagg atctttattt gtttcaaaaa cagggccgag 1016761 attataaaat catcgataaa cagtggaagt cggtgcgcga ccagctcgta agcatgcggg 1016821 taaatggcgg ttttccatat ttgacagtaa acgacggcga ttatatgaaa aataacgaac 1016881 tctatattaa gcattggtat gagggcatag agttggattt gaaatatttg gagaaagtgc 1016941 ttccttattt attccagctt tggggaagaa gcgtgcacat tgagtctgtg cttgaggata 1017001 aggaagtcat gttttcgtac gacggaaaag gtgttcaccg cagatattta taaaaaagag 1017061 gatgcagcgt tctgcatcct ttttattttc cagtttttaa aatcttaaat atgatgtttg 1017121 cctggtccgt attgttaatc aatccgcgga atttttcttt tccggggccg tacgcgtata 1017181 ccggtacttc ttcgccggta tgatcggtac tcgtccatcc gctgttggag cgggtattaa 1017241 aaatcttgat gatggctttg gaggcccctt tgcttttgtc agcctgtgca gctgcttcaa 1017301 cgcttttgat ttcttcagat gtgactttca gattggcata gcgggcgagc acatctttaa 1017361 ccggcttgcc ttcactgatt tttttggcca tgaattcagg tgttttctta gcggagagaa 1017421 tcggttctgc gtgccaattc ttttccccgt ttgcgccaat ggtaaagccg ccggttgtat 1017481 ggtcagcagt tgcaatcaca agtgtatgtt tgtctttttt cgcaaattca atcgcggctt 1017541 tataggcctg ttcaaaatct ttaacctcgc tcatggctcc tactgtatca ttgtcatggg 1017601 ccgcccagtc aatctggctc ccttcgacca tcaagaaaaa tcctttttta ttttggttca 1017661 ggcgatcaat tgctgaaacc gtcatgtctt tgagagacgg tgttttactg tcacggtcga 1017721 gcgctttagc aagccctcca tctgcgaaaa gcccgagcac ctgctgatct ttattttttt 1017781 tcaatgcttg tttagttgtc acatagctgt agccggcttg tttgaattcc tttgtcaagt 1017841 ttctgtcctt gcggttaaaa taagattttc cgccgccgag cagcacgtct attttatgtt 1017901 tgccttttat cttgtcatcc atatagctgt tggcgatttg gtccatgttt ttccgtgatt 1017961 cattgtgggc gccatatgcg gctggagtgg cgtggttaat ttcagacgtg gcgacaagcc 1018021 ctgttgactt gccttgctgt ttggcctctt caagtacaga tttcactttt tttccgtttt 1018081 tatcgacgcc aattgcattg ttatatgtct taacgcctgt cgctaatgct gttccggctg 1018141 ctgctgaatc tgtaatatta tagtcagggt catccggatg cgtcatcatc atgcctgtca 1018201 ggttccggtc aaattctgtt aacttcgggt tattcggtgt gtcaccgtta tttttcatgg 1018261 aacggtaggc tcttatgtaa ggcgtcccca tgccgtcgcc tatcatcaca atgacatttc 1018321 tgatctcagc tttgtcttgt tttttggcgc tggccttttc tgtttgctga agctcagctc 1018381 cggcaaagat tccagctgta aggacagaaa cagcggcgat tggcagaagt tttgatttca 1018441 tattttgaaa caaactcatt tttttcatgc ctcctttaat gtattccgtt tatcatgtta 1018501 gggaaacttt gttaaatgcg gctgttgatc atgtaaacaa taagtaaagc cttgtaagga 1018561 aatgaaaaaa cgcttttcgt tatcttgcct tatttgatgt aaagcattca tttttcagaa 1018621 aaatctttac ctctctgtct ttgcatgata tgtttgttta aataaaaaaa ctgcggataa 1018681 ccacagctct cctcgaatat actttatcac tcatttttcc gatatatgag ccgaccccga 1018741 aagtttttca tttatttcct ttatgttgaa aaacatccca taaaacatga caaaagcact 1018801 cgttttttgt cacctttgca atgaaaatga aatatttaat acccttaaaa actttttttt 1018861 agaacgaata attaagaaat ttgtcacatg aagtcaagac tatttctgat gggaatctat 1018921 ccttataata gaaatcaata agattaattt aaaaaaagag atacatatat atagagttaa 1018981 catttgggga ggaaaatatg aaaaagcaaa tcattacagc tacgacagca gttgttttag 1019041 gatcgacgtt atttgcagga gcggcatctg cacaaagcat taaggtgaaa aaaggcgaca 1019101 cgttatggga tctttcaaga aaatacgaca caacgatcag taaaattaaa tcagagaacc 1019161 accttcgttc agacattatt tatgtgggac aaactttatc gattaacggc aaatctacaa 1019221 gttcaaaaag cagcagttct tcttcctctt cttctacata caaagtaaag agcggggaca 1019281 gcctttggaa aatttcaaaa aaatacggca tgacaatcaa tgaactgaag aagctgaatg 1019341 gcttaaaatc agatttgctt cgtgttggac aagtcctgaa actgaaaggt tcaactagtt 1019401 caagcagctc cagctcatca aaagtgtcat cgtcttcaac ttctacttat aaagtgaaga 1019461 gcggagacag cctttctaaa attgcgagca aatacggcac tacggttagc aaattaaaaa 1019521 gcttaaacgg cttaaaatca gatgtaatct atgtcaacca agtattgaag gtgaaaggaa 1019581 caagcacaag cagctcaaaa cctgcttcat cttcatcgtc ttcaagcagc aaaacgtcat 1019641 ctacatcact taatgtgagc aagctggttt ctgatgcaaa agcgttagtc ggaacgccat 1019701 ataaatgggg cggaacgaca acttcaggct ttgactgcag cggattcatt tggtacgtac 1019761 tgaataaaca aacaagtgtg ggcagaacaa gcactgcagg atactggagt tctatgaaga 1019821 gcattgccag cccgtctgtt ggtgatttcg tcttcttcac aacatataaa tccggccctt 1019881 ctcacatggg gatttacatt ggaaacaaca gtttcattca tgcaggatct gacggcgtac 1019941 aaatcagcag cctgaacaac agctactgga agcctcgtta cctcggtgcg aaaagattct 1020001 aatttttaga gaaaacccgt tcattggaac gggttttttt cattagacgg agcacaggcg 1020061 ttttggttgc tcctaaaaat gaaaatgtga taaaaaatcc aagaactttt tttctttctt 1020121 attttcataa agggcaatcg cgtaagcgcc ggcatagggc agctgtacag actgataagg 1020181 aattctgatc atctgtttct ctgctaactc acgctttact gtagataaag gcagaaatga 1020241 aactccgagt ccttccttga taaaccgttt cgttatatgt gtttgagtga ccttcattgt 1020301 tctcacaaat ggaaatgtca ttctgacttg acggagcaag tcgtcccagt aatcaggatg 1020361 attgtgggtc aaaagcaggt attgttcgag cacctctttg gcatcaattt cgttgtcttc 1020421 tatgaaacgc ttatcgggcg gggcaacaag gacgacaggg tctttgtata agcagtggca 1020481 gcttaaagaa gaagactgta cctttaaaca gcttagtccg atatctgctt ccccggcttt 1020541 aatcagtgac gcgatttccg ctgattcgaa aatcgtaacc gccatttctg tttccgtatt 1020601 cattgctgtg taccgcttca tgacagaagg aagcactgta tctgcaataa gcggagaaac 1020661 cgcgagctgt aaggtttgag agtagccttg tctcactctg tgaagctctg ccatgctgtt 1020721 ttcataatca tcaagaagcc tgagcgcata cggcaaatac gccctgcctt catcagtcag 1020781 ctggatttgc ctgcctttac gctcgaacag cttgcagctg atttcttttt ctaattgctt 1020841 gatatgtacg gtcacagtag gctgagataa gaaaagcgtt tccgccgttt ttcggaagtt 1020901 ctcatatttt gcagcggtca caaaggtgtg aagccatttg aaatccattt ctattctccc 1020961 tctgattaat atttttaatt aattcccttt aaaatattga ttatttttta aatattatat 1021021 ttactataat aacagaaaag gataggggga atacaaatgg tacattacgg attaaaggga 1021081 attacatgtg tagaaacatc catcagccat attgatggtg aaaaagggcg tctgatttac 1021141 agaggacatc atgcaaaaga catcgcactg aatcacagct ttgaagaagc ggcttatttg 1021201 attttatttg gaaaactgcc ttcaactgaa gaattgcagg tatttaaaga taagctggct 1021261 gcggaacgga atcttccgga acatattgag cgcttgattc aatcactgcc aaacaacatg 1021321 gacgatatgt cggtgctgag aacggttgtt tcagcattgg gggaaaatac gtacacattc 1021381 catccgaaaa cagaggaagc aatccggctg attgcaatca cgccttctat cattgcatac 1021441 agaaaaagat ggacgcgcgg tgaacaagca attgcacctt cttcccagta cggacatgtc 1021501 gaaaactact attatatgct cacaggtgaa cagccttcag aggcaaaaaa gaaagcgctt 1021561 gaaacctata tgattctggc cacggagcac ggcatgaacg catcgacttt ttcggcacga 1021621 gtcacgttat ctacagagag tgatttagtg tcagccgtca cggctgctct cggtacgatg 1021681 aaaggtccgc tgcacggagg tgctccttct gcggtgacaa aaatgcttga agacattgga 1021741 gaaaaggaac atgctgaagc atatctgaaa gaaaaactcg aaaaaggaga gcgcttgatg 1021801 ggattcggcc acagggtgta caaaacaaaa gacccgcggg cagaagcttt gagacagaaa 1021861 gcagaagagg tggccggcaa tgaccgtgat cttgatcttg cgctgcatgt agaagcagaa 1021921 gcgattcgtt tgctagaaat ctacaaaccg ggacgaaagc tgtacacaaa tgttgaattt 1021981 tacgcagctg cagtgatgag ggccatcgat tttgacgatg aattgtttac tccgaccttt 1022041 tcagcaagcc gaatggtagg gtggtgcgcc catgtactgg aacaggcaga aaacaacatg 1022101 attttccgcc cgtcagcgca atataccggt gccattcccg aggaagttct ttcataacat 1022161 attttggcgt ttattcattt ctgtcgtgtg gtaacgttca gtatcaacca catgtctagg 1022221 agtgatgaat gtgaacccaa tggacagaca aacagaagga caagaaccgc agcatcagga 1022281 cagacagccg ggcattgagt caaaaatgaa tccgctgccg ctgtcagagg acgaggatta 1022341 tcgaggaagc ggaaaactga aaggaaaagt tgcgatcatt actggaggcg acagcggaat 1022401 agggagagca gcagctattg cctttgctaa agagggggct gatatctcca ttctatactt 1022461 agacgagcat tcggacgcag aggaaacacg caaacggatc gaaaaggaga atgtccgctg 1022521 cctgcttatc ccgggagatg ttggggacga gaaccattgt gaacaagctg tgcagcaaac 1022581 agtggaccat tttggtaaac tcgatatctt agtgaacaac gccgctgaac agcatcccca 1022641 ggacagcatt ctcaatattt caacagaaca gctggaaaaa acctttcgca caaatatttt 1022701 ttccatgttt catatgacga agaaagcttt gcctcacctg caagaggggt gtgccattat 1022761 taatacgaca tcgattaccg cttatgaagg ggatacggcg ttaattgatt attccagcac 1022821 aaagggtgcg attgtttcct ttacgcgttc catggcgaag tcgcttgcag ataaaggcat 1022881 cagagtgaat gcggtggcgc ccggtccgat ttggacaccg cttattccgg cgacattccc 1022941 tgaggaaaaa gtgaaacagc acggcttgga taccccaatg ggaagaccgg gacagccggt 1023001 tgagcatgca ggcgcctatg ttctgctggc gtctgacgaa tcttcctata tgacagggca 1023061 gaccattcat gtgaatggcg gccgttttat ttcaacgtaa tcaacgaaaa accagctcaa 1023121 gagctggttt tttgtgtggt gaaaaatttc aaaataaaaa atttgtcgat ttttctaaca 1023181 attttgtttt catttttgca attttatata taatattgag taggagaaag gaatgattcg 1023241 cgaccagtac aaatatagta gaaaaaaaag aataatgacc attgttactc atgaattcag 1023301 aaaattcaaa taaaatatat aaaaatagat gatcgggagt tgaaggggaa tgaaagggag 1023361 cgtttttagg aagaaaagca ttcaggattt aatcgctgcg acgagcgggg aaaagtcttt 1023421 aaaaagagaa ttaggggcat ttgatttaac gttgcttgga atcggcgcca ttattggcac 1023481 agggattttt gttctgacgg gaacaggcgc agtcacggcc ggtcccgggc tgacgatttc 1023541 atttgttgtg gcggcgttgg cttgtttatt cgccgccctg tcttacgcgg aatttgcgtc 1023601 aagtgtgcct gtttcaggtt cggtgtatac attcacttat gcgacattgg gagagcttat 1023661 ggcctttatt atcgggtggg atttaatttt agaatacatg ctggcggtaa gtgcagtgtc 1023721 ggtcggctgg tctggttatt tccaatcgtt tttatcaggg cttggcattc atcttccggt 1023781 tgctttaaca gcggcaccgg gcgcagtgaa aggcaccttt accctgttta atcttcctgc 1023841 attcgtcatt gtaatggcga tcacatattt gctttattta ggcatcaaag aatcaaaaag 1023901 agtcaacaat atcatggtta tcttgaagat actggttgtt ctgctgttta tcgcggtggc 1023961 agccgtttac gtgaagccgc acaactggca gccgtttatg ccaatgggct ttggcggcgt 1024021 gttcagtgca gcggcgctcg tattctttgc ttttatcgga tttgacgctg tatcctctgc 1024081 tgcggaagaa acgaaaaatc ccgcgaagga tctgcctaaa ggcattattt tctctttact 1024141 ggtctgcacg attttatatg tcaccgtatc agccatcatg actggggtta tcccgtttgc 1024201 tcaatttgcg ggtgtggatc atccggtttc tcttgttctt caaagcgcag ggcaaaattg 1024261 ggtggcaggc atcattgata ttggcgccgt gttgggaatg acaacagtta tgctcgtgat 1024321 gctttacggg cagacccgcg tcatgtttgc catgtcgcgt gacggacttg tgccgggttc 1024381 actttctaaa gtgcatccaa agcacaaaac accttatgta gccacttggt ttttcggaac 1024441 gatgtcggcg cttctcggct cacttgttcc gctggatgaa cttgcaaagc tggtgaacat 1024501 cgggacgttg tcggcatttg tcctgatttc tgtggcagtt atcgttttga gaaagaaaca 1024561 gcctgatctt ccgagagctt ttaaatgccc gggagttccc gtgatcccag gcctggcgat 1024621 tctgttctgc ctgttcttga ttttaaatct gggatgggtg acgattgtcc gcttcctagt 1024681 gtggctgtta atcggcttgg taatctattt cctgtattca agaaagcatt caaaattaaa 1024741 tcaataacct tttgataaag agagcggcca tacaggccgc ctcttttctg ttcttggcaa 1024801 atgaatctat agaaatgaag acaaaaataa gagataatat aggctggaaa ggaagtgacg 1024861 tttattgtct gagcaaaaac cagtccaatg ggcttcgaaa attggtttcg tcatggcagc 1024921 ggccggctcg gctatcggct tgggcgcgat ttggaagttc ccttacgtag cggggaccaa 1024981 tgggggagga gccttttttc ttatcttcgt gttatttacc atcctcttag gctatccgct 1025041 tttggtgggg gaatttattt ttggaagacg gaaccagacg aatgccattg atgcatataa 1025101 aaaagaagcg ccgcgatcag cttggtttct tacggggtgg atcggcgtag cggcgtgttt 1025161 cttagtgctg tcgttttaca gtgtaatcgg gggatggatt ttgctgtata tcgtgaaaac 1025221 agcgtcagga tcactgtccg ggctttctca agcacagtat ggcgctcttt ttgcttctat 1025281 tatccaaaat ccggtgcaga cgctcgcggc tcagcttgtc tttatggcac tgactgtact 1025341 cgttgtcgca agaggggttc aaaaagggat tgaacgggta agcgcggtga tgatgccgat 1025401 tttgttttta ttgtttattc tgctcgttct tcggtctctt acgcttaatg gtgcaatgga 1025461 aggcgtaaag tttctgcttg tgcctcattt cggcgatctg actccggaat ccatattatt 1025521 cgcgctggga caggccttct ttacgttaac actgggggtt tcggtgatgg tgacctacag 1025581 ctcctatttg ccgaaaacac aaaatatccc tcgttcggca gcctccattg tcttgatgaa 1025641 tatcattgtg acactcttgg caggtttggc tatttttccg gcggttttct cattcggttt 1025701 tcagccaaat gaaggaccga cattgctgtt tacagtgctt ccggccgttt ttgaacagct 1025761 tccgttcggc acattgtttt ttatcggctt tctcgttgca tttttatttg cagccttaac 1025821 ctcagcattt tcgatggttg aaattatcgt tgccacaatc ggaaaagggg acgaaaagaa 1025881 gagaaaaaaa ctgtcatgga cgagcgggct tttgatcttt ttggtcggaa tcccatgctg 1025941 cttgtcttat ggcgttttga gtgatgtgca cctatttggc aaaacgtttt ttgatattgc 1026001 cgattttacc gtcagcaatg ttttgatgcc ttcaggcgct ctgttaattt ctctatttat 1026061 cccgctgaaa atttcgaaaa gcgaactctt ggctgaaatg cgaaatggat caaatgcagg 1026121 taaagcattc ttttacacat ggttttattt gcttcgtttt atcgtgccgc ttgccattat 1026181 tatcgtgttc ttaaatttaa tcggaatttt atcattttaa aaaacaggct ccgtttccgg 1026241 ggcctgtttt ttatttaata agatgatatc aacggtgccc atgccgtttt cagtttttgg 1026301 atgccgagcc tgatgtcctc ttctgacaaa ccgccataac cgattaagac agaagtaaaa 1026361 ggcgtctgtt ctatatatga gggagacacg ggatagaggg ttacaccgtg gtcagcggct 1026421 gcttgtattg cttcttcctc acttgctgga aacaaaaggc gcagcagaat gtgaagcccc 1026481 gagttcttac cgagaatctc aacggtgttt cccagttcag agcgaatggc ttctaacagg 1026541 acagcgtgtt tttttcggta taagcttctc attctattta tgtgtttttg ccactctccg 1026601 gtttcgatga agtctgccag tgccaattgc gagtgggcag aaacggtctg cttcattaac 1026661 tgaacattgt tttggatcgg ttccatgagt tcagggggca caatcatgaa gctgagccgc 1026721 aaggaaggca gaagtgactt tgaaaaagtg cccagatata tgactctgcc attcggatca 1026781 agaccctgta aagacggaat gggatggccg ctgtagcgaa attctccatc gtaatcatct 1026841 tctataatga atgaatttgt ttctgccgcc catgccagca gctcctgtct gcgggtaatc 1026901 gtcataatgg tcccaatcgg aaactgatgc gaaggagtcg tatacatgag ataaggattc 1026961 tgacggtaga gctcatccgg caggacgcct tctgcatcag aacaaatcgg agtgacatcc 1027021 atgtgatttg cttcaaacat ccttcttgaa cggtgaaagc ccggttcttc aaagccgatt 1027081 tttgtacctg gctttagcga aaggcaaaga ttttgcagaa gcacggtggt tcctgcgccg 1027141 atgataatct ggccgggttc acaatttact ccccgagaca gcctgacgaa tcgggcaatc 1027201 atgtgcctga gttcgtattc tccttgaggg tcgccagagg tgtgaaacga tccggaatag 1027261 cgatcaagac tttttactat gctttttctc catgcgttaa agggaaagag ggtcggatca 1027321 acgctgccct gatggaagtc aatagcaggt gcgttttttt gatgtaatcc cggctgtaca 1027381 gactgctgaa aatggtcagg agctgtcggg aatcctggtt ctacttccgc cgcgaaccag 1027441 ccgattttcg gcttgctttt gacatagccc tcagcagtta attgctcata agctcgttct 1027501 atagttgccg tgctgacatc gagcaagctg gagagcctgc gttttgacgg aagtcttgtt 1027561 ccctttgtga ttcgcgcatg tgaaatttct tgtttaaaaa aggtataaag ctgttcatac 1027621 agcggtgttt tgctcttttt atcaagaaac ggcgtaatat ccatctcatg tctcctttgt 1027681 agctggcatg gtcatttttt ctgatattgg ctatttggca aatgccattt attagctatg 1027741 atcattgtaa cgaaaggaaa ggggattgag aagatgatcc atatgaaaca attaacctcg 1027801 aaagaagaat gggctgagtc gtatccgatt atgagtgaat tgagaacaga actggatata 1027861 gagacgtatt tacaaaggct tgaagcctgt gtgcagaaag aatcgtatat gctgtttgcc 1027921 ttatatgaaa atacagcaat cagagcgctg tgcggggctc tgccgagagt ttccattcat 1027981 aaaggagagc acttgtggat tgcggatctt gttacaacgg caccttgccg atcaaaggga 1028041 tacggcaaaa tgcttttgga ttatgcctca gactgggcga gaaaagccgg actcggtttt 1028101 gtcagtcttt catctggcct tcagcgtaaa gacgcacatc gattttatac agataaaatg 1028161 ggttttacta tagaaagtta tttgttccga aaaccggtat aacgaaaaaa gacgcctgaa 1028221 aaggcgtctt ttttaaaagc caaactgtaa attcgtatct acagatacaa tggtatacac 1028281 acaaataatc acaaagagat taaggatgac gccgagcagg cctggacctg tgcgccctct 1028341 cttgatgaag agttcaacaa cgccgaacgg aacggcagcc atggcgaacg gaagcatttg 1028401 ataggaataa aacgtgacgt tgctgataat ggccaaattc agcaacagca gggacagaac 1028461 cgctgtcccg acagagatcc agccgaatac attgtgttct ttaaaaattc ttaccagttc 1028521 cataattcca cctcgccgac attcgctgat tttacagatt tatttttcag catgcgctgg 1028581 atttccttgg ttggccctgt aacgaccgaa ccgtatacat tgacaccgtt tttctctaca 1028641 taatctaatc ggttatctac attcaggtct ttccgttttg aaatgacctg agcccatttt 1028701 tcgtgtttgg acatgaattt cagggcgttg ataaactgat cgccattcga cttgcctttt 1028761 gtattaaggg cggccaagaa ctttgaatcc tttccaggat agccaagagg ttctgtggaa 1028821 gctgtcttat ttgtgttttt ctctgtttcg attgcgttcc acaaaaagct cacatcatag 1028881 cctttgaatt tgttatacac gtcttttgtc ggatatgcac ggtcatatga aaggtagacc 1028941 tctgataccg ttccttcagg caatgtgctt aacgtttttt ctgcttttgc ggtcgtttgt 1029001 tcagacttgt ttgaaggatg tgtaaagtaa tggccggttt tattcacttc taagtcatag 1029061 tagtttactg ccggcgcttt tactttgtta taaaacattt caacccgttc attccctacg 1029121 gcagccgtct tcgtgccaat ctgcttttgc agcgggaatt ccgtattcat tccaaatagc 1029181 ttcacttggc ttttcagtcc ggaagtatca acaagaacat tcggcatggt cagggctaca 1029241 gtgactgcgg cagtttccat aaactcattg ccggtgctgt gttttccacc cattccgtaa 1029301 tagaggtagc ttcccagcgt acaaagcggc aaaatcatca atgtcgaaat gacggcaagc 1029361 acagaaattc gcaaataaga cttgcgtttg ccgtaggcta aaatcgcttt ttgtttttca 1029421 ggactgatgc tgagatccca atcgttatcg tcctctagtt cgctgtcaat cagttcctga 1029481 tatacttcaa gcttctcgag ttcttcctca aatgcagtca tttcctggtc gctcatttcc 1029541 ccatttttat attgatcaaa acgcttttta aattcttcat tcatcattaa cacctctatt 1029601 ataaagtgct ttcagccgct gtctggcacg aaataaaaca cttttaaaat tcgcctctga 1029661 aatattcata atatgggatg cttctttgta gtttaactct tttaaataat atagcgttaa 1029721 ggcctcccga taattatcgg ggagctcgga catataacca gtcagcactt cctttatctc 1029781 tacctgatgg gcaggacttt gaacagcatt ttgaaagagg cttccgatta agtcatcaga 1029841 aatggttact tctttcttat gctttctgac gtaatcaatg aaggcgtttc gcgccacttg 1029901 aaaaagccag ggctttactt tgctgtgatc ataggagtga atgtgtatgt atgcccgcat 1029961 aaaggtttcc tgcagtaagt cttcagcaag atgcttgtct tttgtcatgg agagcaggaa 1030021 cctgtaaaca tcattcatgt acatttggta aatttcatcg atcgtcactg ccttttctcc 1030081 cctctatgtt atacacgcat aagaaaggtt taaagttgca cattacatgc aaacggcttt 1030141 tttataccta atcaaacacc attactatat agtacccaaa aatggccgca aaagatagtg 1030201 cggagaaagg tttaacattt tttccagagg ggaaaagata gtgaaaaagt gaaggagtgg 1030261 cacaatggaa tataccagta tagcagatac aggaatagaa gcctccagaa tcggcctcgg 1030321 cacatgggcc attggcggaa cgatgtgggg aggcactgac gaaaaaacat cgattgaaac 1030381 aatccgcgcc gctcttgatc aggggattac actgattgac accgcaccgg cttacggctt 1030441 cgggcagtcc gaggaaattg tcggaaaggc aatcaaagag tacggcaaaa gagaccaggt 1030501 gattctcgca acgaaaacgg ctctggactg gaagaacaac cagctgttcc gccatgcgaa 1030561 cagagcgaga attgtagagg aagttgagaa ttctttgaag cggcttcaaa cagactatat 1030621 tgatctttat caggtgcatt ggcccgatcc gcttgtgcca attgaagaaa cggctgaagt 1030681 catgaaggaa ttatatgatg cgggaaaaat ccgggcgatt ggcgtcagca atttttcaat 1030741 tgagcaaatg gatacatttc gcgccgtcgc acctctccat acgattcagc ctccatataa 1030801 tctgtttgaa agagagatgg aagagagtgt ccttccttat gcgaaagata acaagataac 1030861 aacattatta tacggcagtt tatgcagagg gctgttaaca ggcaaaatga ctgaagaata 1030921 tacatttgag ggcgatgatc tgcgtaatca cgatccaaaa ttccagaagc cccgctttaa 1030981 agagtatctt tctgctgtga atcaattgga taagctggcg aagacacgtt atggaaaatc 1031041 agtgattcac ttggctgtca gatggatctt agatcagccg ggagcggata tcgctctttg 1031101 gggagcaaga aagcctgggc agcttgaggc cctatctgag attacaggct ggacgctgaa 1031161 cagtgaagat cagaaagata tcaatactat attggaaaat acgatatcag accctgtcgg 1031221 accggagttt atggccccgc cgaccagaga ggaaatataa caaaagctga gggcgaatcc 1031281 tcagcttttt ggcgtttaaa cgagagaaat cttaaaaatt agtaccaggt aataaaaaat 1031341 attgttataa tagatgacag aaagaatcat tgattacgac aaaggaagtg cgatatgtat 1031401 aagttttgtg caaatgcttt aaaagttatt ctttctcttc gcggaggagt gaaggtgtat 1031461 aacaaagaaa accttccggc cgattcaggt tttgtcatcg cgtgtacaca ttccggctgg 1031521 gttgatgtga ttacactcgg agtcgggatt cttccttatc aaatacacta catggcgaaa 1031581 aaagagcttt ttcaaaataa atggatcggt tcgtttctga agaaaattca tgcctttccg 1031641 gtagatcggg aaaatcccgg gccaagcagt attaaaacgc cgattaagct gctgaaagaa 1031701 ggagagatcg tcggtatctt cccaagcgga acaagaacct ctgaggatgt gcctttgaaa 1031761 agaggtgcgg tgacgattgc gcaaatgggg aaagcgccgc ttgtccccgc tgcatatcag 1031821 ggcccttcaa gcggaaaaga attattcaaa aaaggaaaaa tgaagctgat tatcggtgag 1031881 cctcttcacc aggctgattt tgcccacctg ccttcaaagg aaagacttgc agcaatgaca 1031941 gaggctttga atcagcggat taaagaacta gagaataaac ttgatcagct ataaggcgtt 1032001 ctgagagatt gtcctgaaac tgtgaaaata agaaaagcac cctatacaag gtgcttttct 1032061 tattatgctt cctgctggtt agctgtctcc agaagttctt cttcttgaag ctttttcact 1032121 tcaatatatg cgacgtggtg gccgtcaatt tcattaatga tgaattcgca gccctcttcg 1032181 atgatggaat catctttttc aacatcgtat ttttgagtaa ggaaccagcc gccgattgta 1032241 tcgacttctt cgttctctaa atggatgcct agcaggtcgt ttacttggtc aattaacact 1032301 tttccgtcaa gaatataatg gccttcgccg attttgcgga tttcgctaat ttcatcaata 1032361 tcaaattcgt cgcggatttc accgacaatt tcctcaatga tgtcctcaac cgtcacaagc 1032421 ccggcagtac cgccgtattc atcagacaaa atggccatgt ggaccctctc tttttgcatt 1032481 ttgacaagca ggtcttggat cggcgcagat tcaatgacat gaatgatagg gttgacgaat 1032541 tgagaaatgg tggaatcaac agatacctca ccgctgatgc aggcggtcag cacttcttta 1032601 atgttaataa ccccgataat gttatcttta tcgccctctt ccacagggta gcgggtatat 1032661 ttttcaatct gaatgatgtc catcatttca gaaatcttga tatcatgcgg aaggctgaca 1032721 atttcggtcc gcggaatcat aatttctttc gcgagcctgt cgtcaaattc aaagatttta 1032781 ttcacatatt taaactctga ttggttgatt tcaccgcttt tatagctttc agacaaaatg 1032841 attcgcagct cttcttctga gtgagccagt tcgttttctg aaacggtctc caggccaaat 1032901 gctttggtca ataaccgtgc ggaattgttc aaaagccaaa tgaatgggaa cgcgatgcgg 1032961 taaaaccaaa tcagcggttt cgcaaacagc atagacactg cttccgcctt ttggatagcg 1033021 actgttttag gtgcaagttc tccgacaaca acgtgtaaga acgtgataat ggcatacgca 1033081 aaaataaacg atatgacatg tgaaagggaa cctggaacgt tcatttggac gaaaagcggg 1033141 tgaagcagcc tttcgatcgt tgattcacct aaaaccccta atccgatgga agtcaatgta 1033201 attccgagct gacacgcaga taaatattca tcaagatgcg tggtcacttt ttttacggct 1033261 attgctgctt tatttccttc cgcgatcagc tgatcgatcc gtgagcctct gattctgata 1033321 atggcaaact cagatgccac gaaaaatgcc gtcagggcga ttaaaacagc aactaaaatc 1033381 aaattcacta tgtccaatta gaaccttcac tctagcaatg agaatgaagg taacacctcc 1033441 tgttagataa aatggtttta acttaacagc agcataaatg attggaacac ggcgagcttt 1033501 tcaggcggga gtttgctttt cagcttgtca cgatcctcgg gcttcagccg ttcaaaccga 1033561 tgcaagattc cggagatgtt ttgattcata tgatcaattt ctaatgccag atttccaatt 1033621 tcatcatcaa gtttagctga agagggaaac tggttctcca gtcgatcttt aatatcggac 1033681 agggccaatc gctgcttctt gcaatctaca ataaatataa gtcgtttgag tgcattttcg 1033741 tcgtagtaac ggtaatttga acaggatctg gccggcgtaa gcagaccgag attcgtataa 1033801 taatcaactg tccgtttcgt tactccggcg agtgccgcta gttcactgat gcgataagtc 1033861 tcagccccat ctatatccct cccaaccatc acgttatagt tatgagaata gtttaatata 1033921 tgaacggtgt cttgcacaag tttattgttt tttttagacc ggaattggaa gttgtggaat 1033981 tcatcatctg attgaagtaa cataggaaga tagaattttc aaatttttat atgcggaagg 1034041 gacagatgaa attggctggg ttatcccggg aagttgaaga aaacttaaat aaaggatcat 1034101 ggattcgcaa gctgtttgat gaaggtgcaa ggctgaagaa ggagttcggg gaagaccagg 1034161 tatttgattt ttcactcggc aacccgattg ttgaaccgcc tgaagctttt aagagagcgt 1034221 taatagagga agctgaaaaa ggcagccacg gatacataca aaaccaaggg cttcttgcag 1034281 cgagagaaaa agtcgcgcaa tttctgggct cgcgttttga agctgatttc tcagcggagc 1034341 gcatcgtcat gacggtgggc gcgggaggcg ctttgaatgt tgcgttaaaa agcatcgtaa 1034401 accctgggga agaggtcatt attcttgcac cttattttgc cgaatataag ttgtatattg 1034461 agaactacgg gggaaaagcc gtcagctgcc cgttgacaag ccggtttgag atcgacattg 1034521 aagcggtaag gcaatcgatc actccacaga cgaaagggct gattctcaat acaccgcata 1034581 accccacagg cactgttctc agccagaaaa atatagacga tttaggcgct ttattaaaag 1034641 aaatagaaga gaagagcggc cagacgattt atgtgctgtt tgatgaaccg tacagtcaat 1034701 taatctatga tgaagagctg gcaaatccgt ttcaatcgta ccatcgtgtg atattggcca 1034761 gctcattcag taaagatctc ggcatagccg gagagcggct cgggtatatc ggattggaca 1034821 gccgaatgcc ggatgcggac cttttgatca acgcttttgt gtattgtaat cgaacgcttg 1034881 gatttgtgaa tgcccctgtc atgatgcagc gggctgtggc acgaatggat gatttaagag 1034941 tagacgcgag cgcttataaa gagcgccggg atttaatggt agacatttta aaagaagccg 1035001 gttttgaatt tgaaatgcca aagggaggtt tctttgtttt tccgaaatcg ccgattgaag 1035061 atgaagttgc attttgcgtg catgccgccc aaaaatacaa attattaatt gtgccgagca 1035121 gcggttttgg aatgagcggg catttccgat tatccttcag tgtgccgatc gagcagatta 1035181 aaaactcacg ggacattttc atttctttat ataaagattt tgcttaagaa ggcaaagaaa 1035241 agaaaacagt tttcaaggct gttttctttt tatatccgca aaatccttcc tcttccaatc 1035301 cagacaggcg cagaattgac aagcaggcat gcagttaagg ctttcttcat gataaaagtc 1035361 taaaaattaa aaatcatttt tggaatgagt tgtgttacaa taaaatatac aatttataat 1035421 caaactttga cttttggagg tggtatgatg gggccctctg cttaggcaac aatacaccgc 1035481 gtacctcaat gttaaggaaa aatgattata tcaggaggtg actccttatc ctttgttgag 1035541 aggatagggt taaatggacg atattgacag tctgatttta attggcgtgc tcattgcttt 1035601 aaccgcgttt ttcgttgcaa gcgagtttgc gattgttaga gtgaggagat ccagaataga 1035661 tcagcttatc acagaaggaa acaaacgggc gatactcgca aggcgtgtca ttacagattt 1035721 ggatgaatat ttatccgcat cccagctagg cattacattg acatcaatcg ggcttggcgt 1035781 actgggtgag ccggcctttg aacggctgct gcatccactg tttgaaccgc tcggcttgcc 1035841 ggactcggtt tcacatgcag tctcttttgc agtcgcgtac ggcttgatca cgttcctgca 1035901 cgttgttgta ggtgaactgg ccccgaaaac ggtcgcgatt caaaaggcag aacagctgac 1035961 tttactgata gcgggccctt tgcgtttatt ctatttgctc ctgtttccgt ttatttggat 1036021 cctcaatgga tcggcgcggc ttttatgcgg gatgttcggt ttgaagcctg cgtcagaaca 1036081 tgatggttcc cattctgagg aagaactcag gatgctgtta tctgagagtt taaaaaacgg 1036141 agagattaat ccgtctgaat ataaatatgt gaataagatt tttgaatttg ataatcggat 1036201 cgccaaagaa attatgatac cgcggaagga aatggctgct gtgtcaactg agatgacgat 1036261 ggccgagatg cttgaagtca tgctgaagga aaaatacacg cgctggccag tcacagatgg 1036321 agacaaagac agtgtgctcg gtttggtcaa tacgaagcat ttgttttctg atttgctgtt 1036381 tatgacagaa gaagaacgaa tgaagatgac gatccatccg tatgtgaggc cggtcatcga 1036441 agtgattgaa acgatcccgg ttcatgactt gctgattaaa atgcagcgcg agcgcattca 1036501 tatggctata ttgtcggatg aatacggagg aacctcggga cttgtgacga cagaggatat 1036561 tcttgaggaa attgtcggag agatccgaga tgaatttgat gaagatgaac agccgctgat 1036621 ccaaaagctt ggcgacggcc attatgtgat ggatggaaag gttcggatcg atcaggtgaa 1036681 cagccttctt ggcgcatcga ttcaagaaga cgtcgatacg atcggcgggc tgatattaaa 1036741 agaaaacatc gatattgagg ctggtgaatc cattcgcatc ggttcatata cgataaaggt 1036801 gctgaagatg gacggccgat taatcaagca aatcgatata aaagaagaag ccggcaacac 1036861 aaccgggatt acggcgcacc acaagctgcc gctgcccgag cctgtgatgc tgaacagtgc 1036921 aaccttgagc gagaaataag ctcaaggttt ttttatattg tgattgtcca gccgcaccaa 1036981 aatgcaaaaa gcgacccgca aagtgtcagg acgatgtaca agatgctttc ttttacacgt 1037041 ttggccataa ggagttgaat agtttcaacg ctgaatgtgg aaaaggtcgt aaaggcgcca 1037101 aaaaaccccg tgccaatgat aagcgagacc gaagcatttg caacgtgaag tcctgtaaat 1037161 attccgagcc cgagagctcc gagaatattg actgtcagta tgccaatggg caggctgaga 1037221 cctttggttt tggcggttat gacattgcca agccagaagc gaagcattgc gccaagtccg 1037281 ccccctatga aaatacccgc tagtgtcatt tttcctgcag cccctttctt tgctgaatgc 1037341 ctgctatgcg ccgtcccaca aaaacaccaa tcagtgcaaa tatgatccct gatatcaatg 1037401 aggctgccac atataaaaga gccaatgagg gttgtccttg caaaagcatc actgtttcct 1037461 tagaaaacgt ggacattgtt gtgaagcctc cgcaaaagcc ggtgcctaaa aaagccgaca 1037521 gcagaggccg ttttgccccg atcataaaaa atccggtcaa aatgcctaat agaaggctgc 1037581 ctgccgcatt ttccagccag gttgccgccg ggaactgacc ggtgtgtatc cataagttta 1037641 atccgtatcg gaggcaggcg ccaagcgcgc ctccgataaa aaccgcgcta tatattttca 1037701 tgtttgccat cctttatgat gaaatccggg taatctgtaa cgatgccgtc cacgcccatg 1037761 gcttgtaatt ttgccgctgt cttttgattg ttgacagtcc atgcaaatat gtttaagcca 1037821 tttttattga tggagccgat catcagacgg ttaagccgtg tgtgttttat attgacatag 1037881 tttgcaaaag agcggaaggc cttcatctga tttctggaca gcatgccaaa gttgggcctt 1037941 gtaatgaccg ctgtcggaat cgaaggataa agctcgcgga acctttggac ggagcggaac 1038001 tgaaaggatt gaacaatatt attgatagaa aaagaaaatt gccctaatag ctgtcccacc 1038061 tcttcttcaa ttccgacttg agacggatgg ccttttagtt caattaaaag gccgattttt 1038121 ttgtggtagc gcttgagcac cgcttccagg gttggaatac gctctccttg aaaagcggga 1038181 ccgtaccagc ttcctgcatc gagtttttgc aattcctcca aggtaaaatc cttaacaaag 1038241 cccgatccgt ttgttgttcg gtcaaccctg tcatcgtgta tcacaacaat ctgcctgtct 1038301 tttgtaagct ggacatccag ttcgatcata tctgcattca ttttcaccgc aaggtcaaat 1038361 gcggcaatcg tattttccgg agcgtagccg gatgctccgc gatgggcaat gatgtacaag 1038421 ctaagtcagc tcctcgtatg ggcatttctg ttattgtatc aaatccatat atgcaccgcg 1038481 atacaaactg gtgaattttt tctgccatat cggaatggtc cgggctgagg aatgcgtata 1038541 actaaaaaaa gacactcagc gtatcagaac acatttcgtc agaaaattag gtctttcgac 1038601 atgttcacaa caaaatatga tcctttataa tagcaaaaaa ggaggcgaga tcatgggaaa 1038661 agggagaatc agagtggagg aaagaattaa agccgaaacg gatgctgaaa tgcaaaaagc 1038721 aactctcctt gatcagacac aaacgaaaaa aggtaagtga ctgtccctat tgaatctggc 1038781 tgatagatga attgagaaat gaccccggcg tttcgccggg gttttgtgct gcataagaca 1038841 tttaaatgaa catccttacg aatattttag tataataaac aattgattgg gatagagggg 1038901 agacagtcat gccggattat ctgcagcagt attttacgct tgataacatc atacaaatcg 1038961 gcatcagctt ggcgattttg ctggtgtttc ttatacttag aaaattattc acaagatatt 1039021 tttttaacct gctttttaat ttgacaaacc ggccgaaaac agaaattttt aaacaggtgg 1039081 ttctggcgtt tgataagccg gccagatggt tttttgttgc ccttgggctg tttttagcga 1039141 tccggtattc accgttttta gatgagcaaa tgccggtcat cagcaaaata taccgctcac 1039201 tgattgtggc gctcttgtgt tggggtcttt gtaatttgac cgcaacatcg tcgtttatct 1039261 tccataaggt gaaccagcgc ttcgagcttg acatggatga cattctggcc ccgtttttat 1039321 ccaaattgct ccgttttgtg atcattgcgc tcagtgtcag tgtgatcgct caggaattca 1039381 attatgatgt caacggattt gtagcgggcc ttggtcttgg cggactggct tttgcgcttg 1039441 ccgcgaagga taccatcagc aacttcttcg gcggtattat cattattact gaaaagccgt 1039501 ttacaattgg tgactgggtg gagacgtcga cagtaacagg atcagtcgag gatattacct 1039561 ttaggagcac gagattcaga acagcacagg gggcgcttgt aacggtgccg aactctacgc 1039621 tgtcgatgga agcgatcacg aactggacaa gaatgaccaa acgccagatt acgttttcca 1039681 tccatgtgtc ctacgctacg ccgattgaga accttgaacg ctccattcat tctctcagaa 1039741 caatgctctt agagcatgag ggcgttgata atgaaataat catggtcaac tttgatacgt 1039801 ttgccgacag ctactacaat ttatttttta acttctatac aaaaacgacg gtttgggctg 1039861 aaaaccttaa tattagagag gatatcaact ataaaattat tgagatttta ggtgcagaag 1039921 gcgttcagtt tgcatatccc ggccaaatgg ttgttgtcaa gcaaaagcac gaaagcgacc 1039981 aattccaggt gaatctaaat aaagaggaaa aggaacgggc ttaaaagaga gacttcgtct 1040041 gacagaggcg gagtcttttt catggtaaaa taagagaaaa aggcggtgtt gagttggaaa 1040101 cattcaaaag tattctacat gaagcacaga gaattgttgt gctgaccgga gcgggaatga 1040161 gcacagaatc agggatcccc gactttcgtt cagcaggggg catttggacg gaggatgcct 1040221 caagaatgga agcgatgagc cttgattatt ttttaagtta tccgcgtctg ttttggccca 1040281 aattcaaaga attgttccag atgaaaatga gcggcagctt tgaaccgaat gaaggccatt 1040341 tgcttttagc tgagctggag aagcaaggga agcaggtcga tattttcacg caaaacattg 1040401 acggtcttca taaaaaagcg gggagcaggc atgtgtacga actgcatggt tctatccaga 1040461 cagcagcttg tccggcatgc ggcgcccgat atgatcttcc ccatttgctg gagcgggagg 1040521 tgccggagtg cacggcggcc ggaaacaatg gggacatttg cggaacggta ttaaaaaccg 1040581 atgttgttct ctttggcgat gccgtcatgc actttgacac cctttatgaa aagctggatc 1040641 aagcagatct tttattggtt atcggcacgt ctctcgaagt ggctccggct agatttgtgc 1040701 ctgaggatgc aagcctgatt cccggcatga agaaagtcat cataaacctt gaaccaacgt 1040761 attgcgacag cttgtttgac atggtcatcc atcaaaaaat cggcgagttt gcccgaagtt 1040821 tgggcatgaa aaagtgagcc gctttatgcg cctcactttt ttattcatga acaggaacca 1040881 ttgtgtcctc taacactccg aaggaatagc ctttttcttt taatttattg attagtaccg 1040941 gcagcgcatt tacagtagca ggaagatcat gcatgagaat tacatttggg cggcttgaag 1041001 agctgtgttc catattctca agctgctgta atacggcggt cacatactgt gaattccggt 1041061 atttccagtc catgctgtcg atcgtccaat cccagtacac aaacccatct ttctccagat 1041121 tgcgaatttg tgaggcggtt agtgacggct tgcttccgta tggcgttctg acaagatcgg 1041181 ttttatatcc tgtaatgtcc tgcagcgtgt cacgcgcctc ctgcatttct tttagcggag 1041241 atgtcggtgt ttgatagaac aatctgttat tgtgggtaac gccatgtaaa ccgagtgcgt 1041301 ggccttcctt ttctgctctt ttcacagcct gcttgaattc gttcatccgc ggtgacagca 1041361 taaaaaacgt cgcttttaca tcagcgcttt tcagtacgtc gagcaagcgg gttgtaacgg 1041421 ctgaagggcc gtcgtcgaag gttaagtaaa ccgttttatc tcccatgttc tgctttgtct 1041481 gcagatgttt tatcaggaga tcgggggagt cgtttttcag cttaaggctt tccttctcat 1041541 ctcgaagctg gccgtttgtt gtgacagtga cttcctttgc tttcgttgaa ctgttggaat 1041601 aacccaaaat caccataagc aaaagcagca cacataaaac tgctaaactt gcaaatttaa 1041661 aagcaagcga aactgcagaa ggagaagcct ctcctctcgt ttgtcgcata acaatctctc 1041721 cattggcata aaatctctac ataatgctgt acagcaggca gcttatgaag atgccttatg 1041781 tttacaacct atgtattacc agtcaagtat acaggaataa aactggaaag cacatagaaa 1041841 atttgtcgaa atgtcagatt ttaaggaaaa aataaactcc tttccgctat agatctcttg 1041901 atctttctgt ttttcagctt gtccaatatg gtagaattag tgataatgac agcttgaatg 1041961 acatcaggga catctcgaaa agggagggct tttatgaagg ttttagtcaa tggccggctg 1042021 attgggcgca gtgaagcatc aatcgatttg gaagatcgcg gttatcagtt tggtgacggc 1042081 atctatgaag tgatcagggt gtacaaagga gtattgttcg gcttacgtga gcatgcagag 1042141 cgttttttca gaagtgctgc tgaaatcgga atttcactgc cattcagtat agaagatctc 1042201 gagtgggacc tgcaaaagct tgtacaggaa aatgcggtca gtgagggagc ggtatacatt 1042261 cagacaacaa gaggtgtggc cccgcgaaaa caccagtatg aagccggcct cgagccgcag 1042321 actactgcct atacgtttac ggtgaaaaaa ccggagcaag agcaggcata cggagtggcg 1042381 gccattacag atgaggatct tcgctggtta agatgtgata tcaaaagtct gaatttactg 1042441 tataatgtca tgacgaagca aagggcctat gaagccggag catttgaagc cattttactt 1042501 agggacggcg ttgttacgga gggtacatcc tctaacgttt atgccgttat caacggcaca 1042561 gtgcgaacac atccggctaa tcggctcatt ctcaatggaa ttacacggat gaatatttta 1042621 ggactgattg agaagaatgg gatcaaactg gatgagactc ctgtcagtga agaagagttg 1042681 aaacaggcgg aagagatctt tatttcgtca acgacggcag aaattattcc ggtcgtgacg 1042741 ctcgatggac aatcgatcgg aagcgggaaa cccggaccgg tgaccaaaca gcttcaggct 1042801 gcttttcaag aaagcattca acaggctgct agcatttcat aaatgaacga agaaaagagc 1042861 ccgcttttta cagcggggct ctttttattt tttaacaaat ccaatcaaaa tggagatcat 1042921 tggcgatata tagaggaaga acgtaaatgg gatgtagtct atgactggaa caccaagtgc 1042981 gctcgccata aatgcgccgc tgacgcccca aggaatcaat gggttaatta atgttccgcc 1043041 gtcctctaat gatcttgtca gaaattttcg ctggatgttt cgtttgtcat ataaagattt 1043101 aaatgattgt cccggtatta atatcgataa atactgttcg cccgttgcca agttgacgcc 1043161 gatgcttgag cagacagttg ctgcaacaag acggcctttt gagcggatgc ctttcatgac 1043221 gccttccaat agtgcagaaa tcaatccgat tttctccatc aatccgccga gtgcaaaagc 1043281 aatcataatg agagagacag agcccatcat ggattgcagt ccgcctctgt taataatttt 1043341 agcggctgcc tcattgtcag tttcgaaagt tgtgccattt tgtaaagctg tcataaacgc 1043401 ctgcaggctg ctgtagggta caaaaatagc agtcaaaatt cccgaggaaa taattccggc 1043461 agtcagaacg gggattactg atacccgttt cattgccagc aaaacgacta agagcggaga 1043521 aagaagggcc cacggtgtca cgtttgcagc atcttttatt ccggttatga cctgctgaat 1043581 attatcggtt gaagcagcgt ccgctgacac tgatgaaccg agaaagtaaa acagaacgac 1043641 agtgatgagc aaagctggaa tggttgtgcc catcatatgg cgaatgtgtt caaagattgg 1043701 tatttcgcct attccggctg caaagttggt tgtgtccgac atcggcgaca ttttatcccc 1043761 aaaacaagcg ccgcatatga ctgcgcctgc tgtccattca agcggaacgc cagccgcgct 1043821 cgccacgccg atcagcgcta ctccgattgt gcttacagtt gtcagacttg agccaacaag 1043881 tgtgctgatg atcatacatg aaaacaaagc agtcaacaga aggtggcttg gttcaataaa 1043941 ggatagggca taaactgtca tagtcggtat tgcgccgctg tacatccagg cgccgattaa 1044001 gatgccgatc agcgctagaa caataatcgg ctgtacgccg tttttgatcc cgtctacaat 1044061 ccctttttca atgctcttcc agggaaatcc aaaccataaa gctgctgctg aaagcatgac 1044121 aacacttaaa aacagcggga tatgaggttc tacatgaagc aagaataagc aagaaataat 1044181 aatgcacaac atgaatataa ataaaccgac ggctaacgga aacgtcagct ttttttgaga 1044241 atccaaaata acaccccata tttatcttta atgcttttgt gcttttgggc acgaaagcat 1044301 tataacagaa aaaaacgaaa atctatgttt tttcacaatt atgaatataa aagaagtgag 1044361 cacagggcgt gctcacttta caatcaggac gggtatatcc gatttcgctg aaagcttttc 1044421 acttacactt ccgaatatta gctttttcag cctgttttgg tctctgcttc cggttacgat 1044481 catatcggca gaaatgcggt ttgcatgctc gataattgat tcagccggat cgccttctaa 1044541 tatatcgata tctccatctg cctgctgttc attcagcatc attctggctt cggcgatgac 1044601 ttcttccgta cggtcttcat agatcattgg ctcaggtgat gttacatccg atatcagcgg 1044661 atcaggaaca cttgtcatgc ctccgctgat atagcttgcc tcagctgcgg gtctgggcgg 1044721 gtcgatgacg gtctgattgt ctttcatatc atgtgaatgg gcgacggtaa tagcggcatt 1044781 tacggtttta gcaagatcaa tggctgtcag aagcgctttc ttactatttt cacttccgtc 1044841 aaacgcaaca atgatacggt cagcatggaa catccttctc accctttcaa agcgtcttac 1044901 aacactacta cccgaatttg agcacaatta accttttcct attcaagtaa tgattgacaa 1044961 taaaaggttt tgtttatatg atgataaaaa gatgaaatca gaatggaagg agggtttgct 1045021 atgccaagga atttgcgtgt ttatcaaaca gtttcatatt ggcgcggcaa accttttgtt 1045081 ctgttttcgt gaacggtttt ttaggtcgga ccgcgcgctg aaaagcgctg tgcgtaacat 1045141 atcggttaaa aaaggcatgg agctgacgct tcatgccttt tttatataca aaatctaagg 1045201 aaagacaggt gtatgggatg tgaagacaaa tacagaggcg agggcagttc gtgccaaact 1045261 ggatgaaaaa agctgcaagg aaaaaataga aggcggctga tgaggagatg gggatagatg 1045321 ttttcagttt tgaaaaagct tggctggttt tttaaggcgt actggctgcg ctatacgatt 1045381 gcgattgtcc ttttattagc agtcaatgtc attgaaatgt ttccgcctaa gctcttgggg 1045441 aacgccatag atgatatgaa agcaggggca tttactgcgg aagggctgct gttttatatc 1045501 ggtatctttt ttgtgctgac ggcggccgtg tatatcatgt cttatttttg gatgcatcag 1045561 ctgtttggcg gagcgaatct gatggagaaa attcttcgta cgaagctgat ggggcatttg 1045621 ctgactatgt cgccgccgtt ttatgaaaaa aaccgaacag gcgatttaat ggcacgaggg 1045681 acaaatgatc ttcaggccgt cagtttaacc acagggtttg gcatcttgac gttagttgat 1045741 tctacgatgt ttatgatgac gatctttttg acaatggggt ttttgatcag ctggaagctg 1045801 acctttgccg ccattatccc gcttccagtc atggcgattg caatcagtct atatggaagt 1045861 aaaattcatg agcggtttac tgaggcccaa aacgcgttcg gggcgctgaa tgacagagtg 1045921 ctggaatctg tttcaggcgt gcgggtgatt cgcgcgtatg ttcaggaaac aaacgatgtt 1045981 cgccggttta atgaaatgac cgctgatgtt tatcagaaaa atatgaaagt ggcttttatt 1046041 gattcactgt ttgagccgac ggtaaaactg cttgtcggcg caagctatct gattgggctc 1046101 ggctacggag cgtttcttgt attccggaac gagctgacgc ttggagagtt agtgtccttt 1046161 aacgtttatc tcggcatgat gatttggccg atgtttgcaa tcggtgaact cattaatgtg 1046221 atgcagcgcg gcaatgcgtc attagatcgg gtaaatgaaa ctctttctta tgaaacggat 1046281 gtgacagatc caaaacagcc cgctgatctt aaagagcctg gagatatcgt tttcagtcat 1046341 gtcagcttta catatccaag ctcaacaagt gacaatcttc aggatatttc atttacggtg 1046401 cgaaaagggc agactgtcgg gattgcaggt aaaaccggga gcggaaaaac gacaattatt 1046461 aagcagcttt tgcgccagta tcctccaggt gaagggagca ttacattttc aggtgtaccg 1046521 attcagcaaa tccctcttga ccgtctccgc ggatggatcg gatatgtgcc tcaggatcat 1046581 ttactgtttt cacggactgt aaaagaaaat attttatacg gaaaacagga tgcaactgat 1046641 aaagaggttc agcaagccat tgccgaagca cattttgaaa aagatttgca catgcttccg 1046701 tccggtctgg agacaatggt cggtgaaaaa ggcgtggcac tgtcaggcgg gcagaaacaa 1046761 agaatttcga tcgcgagagc actcatggcg aatccggaaa tcttgattct ggatgattca 1046821 ctttccgctg tagatgccaa aacagaggct gcaattatca agaacatcag agaaaaccgc 1046881 aaaggaaaaa cgacatttat tttgacacac cgattatccg cggtagagca cgctgacctg 1046941 atccttgtga tggacggcgg cgtcattgct gagagaggca cgcatcaaga actgctggcc 1047001 aataatgggt ggtaccggga acaatatgaa agacagcagc tgttcactgc ggaagaaggg 1047061 ggagcagggg catgaaaata ggaaaaacgt tatggagata cgcacttctt tatcgaaaat 1047121 tgctgatcac agccgtcctt ttgctaactg ttgccgtcgg tgcagaactg actgggccct 1047181 ttattggcaa aaaaatgata gacgaccata tcctcggcat tgagaaaaca tggtatgaag 1047241 ctgcggaaaa agataaaaat gccgttcagt ttcacggcgt ctcatatgtc agagaggacc 1047301 gattgcagga gcctgtttca aaagcaaaag aagcgcatat ttatcaagtg ggaatggcgt 1047361 tctattttgt tgatcaggct gtcagcttcg acgggaatag aacggtttct gacgggaagc 1047421 tgacgatcac aaacggagac aagagccggg catatgctgc cgaaaagctg actaagcagg 1047481 aacttttcca gttctatcag ccggaaataa agggaatggt gttactgatc tgcctgtatg 1047541 ggggcttgct tgtgttttcg gtattctttc aatacggaca gcattatctg ctgcagatga 1047601 gcgccaatcg gattattcaa aagatgaggc aggacgtgtt ttcgcacata cagaaaatgc 1047661 cgattcgcta ttttgacaac cttccggccg gaaaagtcgt tgcgcggatt accaatgata 1047721 cggaggctat tagggattta tatgtcacag tgctttcaac atttgtgaca agcggaatct 1047781 atatgttcgg gatattcacg gctttgtttc tgcttgatgt gaagcttgcg tttgtatgtc 1047841 tggcaattgt gccgattatc tggctgtggt cggtcatata ccggagatat gcgtcatatt 1047901 acaaccaaaa aatccgctcg atcaacagtg acattaacgc aaaaatgaat gagtcaattc 1047961 aaggcatgac cattattcag gctttccgcc atcaaaagga aacaatgaga gaatttgagg 1048021 aattaaatga atcacatttt tatttccaaa acaggatgct gaatttaaac tccttaatgt 1048081 cccataatct ggtcaatgtc atccgcaatc ttgcgttcgt ctgtctgatc tggcattttg 1048141 gcggtgcgag cctgaatgcg gcggggattg tttctatcgg tgtgctgtac gcgtttgtcg 1048201 attatttgaa ccggttattt cagccgatca caggcatcgt caatcagttt tcaaagctgg 1048261 agcttgcaag ggtctccgcc gggcgtgttt ttgaactgct tgaagaaaag aatacggaag 1048321 aagcgggtga accggcgaag gagcgcgcgc tggggcgggt tgaatttcgt gatgtgtcat 1048381 ttgcgtatca agaaggtgaa gaggtattaa agcatatttc ctttactgcg caaaaaggcg 1048441 aaaccgtagc gctcgtcggc cataccggat caggaaaaag ctcgattttg aatcttctgt 1048501 ttcgttttta tgatgcgcaa aaaggtgatg tcttaattga tggaaaaagc atttacaaca 1048561 tgtcaagaca ggaactcaga tcccatatgg gtattgtgct tcaggacccg tacttattct 1048621 cgggcacaat cggatctaac gtaagtctgg atgacgaaag aatgactgaa gaagaaataa 1048681 aaaatgcact gcggcaagtc ggtgctgagc ctcttcttaa gaagcttccg aagggcatta 1048741 atgagcccgt gattgaaaaa ggcagcacgc tatcctctgg agagcggcag ttaatttctt 1048801 tcgctagagc tttggcgttt gatcccgcga tcttgatttt agatgaggca acggcgcata 1048861 ttgatacaga gacagaggcc gtgatccaga aggcgcttga tgtcgtcaaa caaggacgca 1048921 ccaccttcgt catcgctcac cggctttcaa caatcagaaa tgctgatcag attttggttc 1048981 ttgataaagg agaaattgtt gagagaggga accacgagga actgatggca ttagaaggcc 1049041 aatattatca aatgtatgaa ctgcaaaagg gacagaaaca ttccattgca taacgctcaa 1049101 aaacccaaaa caatcgtgtt ttgggttttt ggtttatgta gtcaataagc cagtccgaca 1049161 cggtttccga catactcacc tgtaacgagc tcacgatata aaaagtccgc agtatcgccg 1049221 accgaaatgc ttgtgccgcc ctcaggcaaa acgttacgct ccgtacgata aacgccggtt 1049281 gctgttccgt ccgggaggta agtggggcag atgattgtcc agtctaatga tgattcttta 1049341 agcatttcgt atacttttgc atgctccttg gctgcgcggg tctgctttcg tttcgattca 1049401 tttgtttcaa accggtattt tcccggttca tatcgggaat ctaggatccc tgcggtgccg 1049461 atcgtaataa gccgtttgat atgctgttcc tccataacgg agagaatgtg tgccatagca 1049521 gttgacaagg tatcatcacc atctgtgcct agacagctga tcacgatttc agcattctcc 1049581 attatttttt tcacatcttc taagcggcgg gcgttcccca tgacagttct gtcttttgaa 1049641 aggggaagat cagcatgttg agatctgatc agagcgaaaa tatcaaatct ttcatctgct 1049701 gcagcttgtg ttaaaaaggc ttgtccgacg cggccgctgg ctcctaataa agcgattttc 1049761 attaaaaaac ctcctcgcct ttcattataa aaggatgttc tcagtttgaa cagcgcggga 1049821 aagaatacct gtacaaataa acagaacgat gggaaacata ttcatgaatc atggatacac 1049881 ttacgaattg aaccagctcc caattcacaa tggtgatgaa tgacaccccg attccctccc 1049941 tttttttcta ggatatgtgg agcaggaaaa aagggtgaca aaataaagag agcgcggaaa 1050001 ccgcgccctc tatagccata tattgaattg ttattgaact ctgccgccca tttgctgctg 1050061 agcgaaagat actaaacgtt ttgtgatttc tcctccgaca gaaccgttag cgcgagaagt 1050121 tgtgtccgct ccaaggttaa cgccgaattc agaagcgatt tcaagtttca tttgatcgat 1050181 agcctgagct gcgccaggaa ctagtaagtc atttgaagag ttttggttag ccatgtgtaa 1050241 aatctccttt ttatttagta tggttgggtt aactggagtt gcaccaatct gtgaaccctt 1050301 ctcgggtgtc actgccgcct cggcgtaacc caatgctttg ccggcttgtt actacgtatt 1050361 atgttaaaat ggccggaaaa tcatgcggag aattgtgtgg taaatcttga gaaataaaaa 1050421 aagcttagcc gtttaggcta agctagtcat aaatatgaaa aagcatcagt tcatgtatct 1050481 cgtttgtaag agcaggctcg tcagcgcggg cgggaaacaa gtctccccat tcaatctcac 1050541 cgctcttatg atagatgcct tcataatggg tccctttata ataaaatgaa attttccatc 1050601 cgggcagctt ttcttttggg aacaaaggtt tccagctgaa atgagaaatc attacggcca 1050661 cgctccttac atttggtatc aattgaccta aataaaaacg gcttatgttc attgtatcat 1050721 tgtttcagaa catcattgaa gaggcctaaa tatgcagttt gtcccagctt tggataaaga 1050781 taagcccgct ttattaaaaa agcggacagg ttacgaaggc cacaatgctt ccggagatgt 1050841 gattgccttc tcagataaat atgacgcgta ttcaaaactt cttcgttttg taagagaatc 1050901 aacatgatgc aaatttggat gagaaaaaat gcttcggccc gggcgcgaat tcgcttcaaa 1050961 catccatact ttaccgttct gatcaatgcc aaaatcgaaa ccaatctccc cgataaatcc 1051021 ctcgatatga tcatgaagga catggcttgc agtcagtgcc gctgcagaaa gctttttaat 1051081 gacctcaact ctttcagcgg gatcatcgta tacttccgca agtgtcttta cagtgccgcc 1051141 gttagaaaga tgtgttgtaa tgctgttctt tccggaaatt tttacggcga ttgctgtcac 1051201 tgtccatttt ccttttctgt ttttattggt atggacacgg aaatccgctg gtttgccttg 1051261 aaattcgatg agatcaacac cttgctgaat gagaaagtcg gacgggttgt gatgtttttg 1051321 aaattctgca aggaatgagg cggcatcgga ataatcaatt gatgtaaaag ttttggcgtc 1051381 attcgtatgc tttaccgtca ggccgccatc tgttcttgtc agctgataaa tgccggtgcc 1051441 gagtgctcca tttgccggtt tgatatagac ttttttgtat gcgccacaga gctcatctat 1051501 cagctccaca gacggtgtca gctcggatct aggcaaaaag ggtgccgttc ttggatcttt 1051561 ttcgagcaat tgatgaacgt tccatttatt gaaaaacgtt ttattaaacc atgggatctg 1051621 atattcatcg atcagcctct tttttgtatg ttgcaagaga agtgaatctt caatttttcg 1051681 gttcggcaaa cggtcataaa cgacgttcgg caatggaacg atttttttct cccagccgtt 1051741 ttccctgtaa aggaggcctt caatcgtgcc ttcctcccaa ttgatttggt gcgcgccaaa 1051801 aacgaagcag tagcccccgg cttgctcgtg taacgtgaca agtttagaaa aaaagaggga 1051861 acgatcctta aatgggcgtt caagagatac agtaaaccct gccgtaaaga tgccgactaa 1051921 cggcccgata tgcactgtat gatcatgaat cagtatatct gccctgcttc ggtggggaag 1051981 caaaagctca tgaaacagat tttcagagag aagcacggtt tgttccagat gccgtctgta 1052041 agcaacgtgg catctgacaa ccttcgttcc gaatgcggca tgcaaaagtc cgtcttgctt 1052101 cagcgaagag ggcagaaaca gggtgttttc actggttttg tctatgccga tcaaaaaccg 1052161 tttaggattc acgcggaaga actcctttct ggctttgctc agaaaacaga tattggcagc 1052221 gttttagggg acaagtgtac agctgttctt tttgctcggg agagacacgc aggattgact 1052281 tcctgcctgg tttggaattg atatctaaaa tccaaattct cccgtccttt gcaagacata 1052341 tatcaagacc gagttcaaac aacggcccat agcgctcgtc aagataatac ggaaccgatt 1052401 gggtaattga aaacacatca tctagtaaaa ccacttgctg ttttttcggt atatcttcaa 1052461 accaggagtc aaatgtcagc gcatcagatc cgcctgacaa attggccagc agcccgtgtt 1052521 tgtatccgcg tcttactgcc tttccgactg tattccattc acctgcttcg tttttttcca 1052581 taaacagacg aatatcacaa gggtattgtt ccttatcttg aatgtttaag taaggctgaa 1052641 gcaaatattg atgctgaagc acttttttgc accatgtttt aaaagaagtc tggttggaaa 1052701 acgtttttgt ctgcttatcc tttccgatgt gataagtagc agtgatgttt ttcttgccca 1052761 gcttcaaaag aatcacgcct ctgcctcccg cgccgaatgc cggtttaagg atgcaggctt 1052821 tttctttgga taaaaaggag tgaatttgtt cgtagcggct cacctttatc gtttcgggaa 1052881 tatagggatt gattacagag tgctgctgca aatcgtgaag gacggtccac ttatcgggaa 1052941 gaccccgccc gataaattcc gttttcggat attttttgag ccactcaacg attggttttg 1053001 ctttttggga atgtgaatcc ttgccgtaaa aacagcgatc ataaatataa tctggaatcg 1053061 ccatttcagt ttcgttccat gtgctgctgg ccgaatgata gaccgatgct ttgacacgca 1053121 aagtgtcagg tgaaatatca aatggtgtaa accggatgaa acgtatgccg aattcgggtg 1053181 ctcttttggc cagttctgcg gaataatccg cttcatgctg gcgggataag gacataaaac 1053241 cgagtgttat catggtgaga ctcccccttt tattcaaaag ctgccggcgg gtgtccgcag 1053301 ctttacacta aatacatgta agacgaacgc agctgacggt attctacttt acagaatacg 1053361 attctccacc ttgccctatt ccaaaagaac aagctgattt tctaagaaca ggaatttgtc 1053421 tcctcgtttg ctaagtgatt gcatgagcct ctataatacg tataggtaca taatctatat 1053481 gaaaaaagct gaagcacaga tggaggaaga tgaataggaa tgggtattgc aggaaccttt 1053541 atttttatga tcgtgatcgg cgctgccatt ggagcggtga ccaatcattt agcaattcaa 1053601 atgctgttta ggccgtataa agcgtactat ttgtttggga aacgagttcc ttttacgccc 1053661 gggctgattc caagacggcg agatgaactt gcaaaacaaa tgggactgat ggtagtcaat 1053721 catctcttaa cccctgaagg cattaaaaag cggctcgtct ctgatgcagc caaaacgcag 1053781 gctcttcgag tgggggaaca gctgattcaa aagctgtcac tttctgaagt gacagtaaaa 1053841 gaagcgcttg aaaaagccgg gatgaagcgc cccgaaaaag ctgctgatgc atggatcagc 1053901 agctggaccg atgataagct gcatgagctt ttccgccaat acggggacca atcgttaaaa 1053961 gagctggtgc ctatagaggt gcaggaaaag cttgaggaaa aaattccgat gatttcagga 1054021 tatatattgt cacggagtgt ccgttatttt gaaagtgatg aaggaaaaat ccgtcttggc 1054081 aatatgattg atgacttttt aaaagagcgc ggcatgcttg gaagcatggt gcaattgttt 1054141 cttggcaatt caagccttgc ggatcgcgtg ctgccggagc tgctgaaatt cttgcgcaat 1054201 gaggaaacaa ataaattgct ttctgatctc ttaaaaaacg aatggggcaa gctgagggag 1054261 tatacgttta atgaagcaga tgaaaaatgg aatgcaaagg cgctcatttt cagtttgaaa 1054321 cgaagagtgc tgcaagcatt ttcgactgcc cctttcttca acaatacgat tggcacgctt 1054381 accgtccgct atgaatctga gctgacccag caaatgctgc cggcactatt agacaaattg 1054441 cttgaaggta tttcgtccaa ccttgaaagt gtcttaaaac ggttgcgtct tgaggaaatc 1054501 gtcaaggagc aggtggatca gttcccggtg gagcgtcttg aagaaatggt gctgtccatt 1054561 tcaaaaaaag aatttaaaat gattacctat ttggggggcc ttctcggcgg aattataggc 1054621 gcgattcaag cattgtttgt catccttttt taagaagaaa tggtttttga ttaatgaaag 1054681 gagctccata gtctgttata gtggagtggt atgtcaaacg gcaatgatga aaggagctat 1054741 ttacaatggc tgttaatttt tatgatgtag cgtatgatct ggaaaatgca ttacgcggga 1054801 gcgaagaatt cacccgttta aaaaaccttt acgacgaagt taacgcagat gaatcagcga 1054861 agcgcatgtt cgaaaacttc cgtgatgtac agcttagact ccagcaaaaa caaatggcag 1054921 gagaagagat tacacaagaa gaagtgacgc aggctcaaaa aacagttgcg cttgtacagc 1054981 agcacgaaaa aatttctcag ctgatggaag cggagcagcg catgagcatg ctgattggtg 1055041 aattgaacaa aatcattatg aagcctttag aagagcttta cggcagtgtt gaaggctaat 1055101 aagcaaaatc ccttcttgga taagaaggga ttttttattc actcagcaaa cttggaaatc 1055161 caatgaatct tttacctctc cattgatgat gactgataat gtatgaattc ctttgtaatg 1055221 ctttctggtg gttaaatcct taaaggattg gattcttgtg tatgacttcg tttcgttttt 1055281 tcgtatattt gtttctgtta ttttaaatac tttctgatga cgctggcctc ttgcttttac 1055341 aaaatcaatt gcgtactcaa ttcttacttt ttgatccctg tctgaatgaa tatagaaaga 1055401 aaattcaagg ctttcgccaa taactatacg tttgggctgg catgttaaat catgtagttg 1055461 tatcgaatca gcattttcat aaccaaaaag cgctaaggcc tgtttatcac ccttttttaa 1055521 taaggtccga taggcgtgtt tgataatcca gtctgtatgg ggatgtgttc cgtaccattg 1055581 atctgcgact tttctcagta aatgaggatg cgtttttgat atatcattaa ggttgttggc 1055641 cacgcttttt cttacatata aagactcgtc ctgcatcagc ttctcaagga tcggcaatac 1055701 gggggaaggg tccgatttca aagccggtat cgattttccc catggcaggc ggggcctgct 1055761 gccttcgctc gcaagtcttc tcacgtgttc atttttatgc tcagaccatg caagcaattg 1055821 tgcaatcatc ttttcttgat ctaacagcaa aaaaggcctt acagcaaatt ctgaggtcga 1055881 atattgcgta aaggattcca atgcctttat tgattcttcc caatgcgcta acccgtactg 1055941 ttccacataa tctggaaata aaattccgct gagtccttta aaatgagggg ctgtatcccg 1056001 taaaattgtg agcgcttcaa cgtattgttt tggcaaagtt tcgtataaag aaactgtcac 1056061 gcggcgcatc cgctctttta aagtgagttc aggccagtcc tccagccgta atgtatccaa 1056121 gaatctgttt ttgttaaaat caggatagga tgaccttaca tgatggatca actgagatat 1056181 cagttcttca ttatatattt cttttaaatc agccatataa acaccgcttt ttcgtttatt 1056241 atttatattg tatgggaatg tacgttctgg atcaagtgta tagtcctaaa aattaacaac 1056301 tgatcctacc acggatatac aaaagttggt tacttttttt agttaaaaaa acccttgtca 1056361 tcggaaagga aaactgagat aataacattg aaagcgccta cacttaccta tttcaaatgg 1056421 atacggtcgc atatcatgcc gttatataga ggggataagc aacagagagt aagtgttcgg 1056481 agcgcatcat tggtcaaaca aggggttcct gatacatgat ttttcgtaaa tcgaaataac 1056541 gatattaggg agaatggctg cttcgatcgt atcctatcaa caagccatac ataaagtctg 1056601 ctgagccagg ctttttttgc tttaagaaaa ggttgttcta aacacagaga cagggtcata 1056661 tcctatacac aagtacagtc atcaaggagg gggacatctc tgtgtcaaaa caattgcttg 1056721 ccttaaatat agatggagcg ctgcttcggt cgaacgggaa gattcatcag gcaacgaaag 1056781 acgcgattga atatgtaaag aaaaaaggga tttacgtcac acttgtgacc aaccgtcatt 1056841 ttcgctcagc acagaaaata gcgaaatcgc taaagcttga tgccaagctg atcacccata 1056901 gcggggcata tatcgctgag aaaattgacg ccccgttttt tgaaaaaaga atttctgatg 1056961 atcatacctt taacattgtt caagtgctgg agagctatca atgcaatatt cggcttcttc 1057021 acgaaaagta ttccatcgga aacaagaaaa aggtgaattc gaatttatta gggaaagcac 1057081 tcattcatcc gtctgacccg atcttttatc cagtccagtt cgttgaatca ttaagcgatc 1057141 tcctcatgga tgagccggtg agtgcacccg tcatcgaggt gtacacggag cacgacattc 1057201 agcatgacat tacagaaacg attacaaaag ccttccctgc ggtggacgtg attcgcgtaa 1057261 acgatgagaa actgaatatc gtcccgaagg gtgtctcgaa ggaagcgggt ttggccctcg 1057321 tcgcttcaga gctgggcctg agtatggatg atgtcgtggc cattgggcat cagtatgacg 1057381 atctgccgat gatcgaactt gccggtcttg gggtagcgat ggggaatgcc gttccggaaa 1057441 ttaagagaaa ggcagattgg gttacaaggt ccaatgacga gcaaggtgtc gcttatatga 1057501 tgaaggaata tttccgaatg cagcagcgaa aaggatttct tgataagttc cacatgaaac 1057561 gtgtgtaaaa aagccgctcg cgccctgaca ggtgcggcgg cttttttgcc ggattgattt 1057621 tagcagttta tttctgtaca ctaaagaaag ttttgaatct gataaattag gtgatgaagt 1057681 tgcaaattaa aatagaaggc atacatgatg accgcctgca tcggcctctg caaaatattg 1057741 caaatttgtt ttatgaagag tgcgagcttg cgtatggcgg agaggagccc gcagattttg 1057801 tcatttcttt agcgttgtca caaacggatg agcatgtgac ggtttctgga gaagtgaagg 1057861 gtactggcat aaaggaacag catacaaaat tcttttctcc agacatgact gaaaaagaag 1057921 cttttaagca agtgaaaaac acaatttctt atgtgtatct caatcttctt caggcgcata 1057981 cgggcattac gcagaagtgg ggaatcctca caggaatccg gcccacaaag ctgcttcata 1058041 aaaaactgca aagcggaatg tccaaggagc aagcgcatgc tgagttgaaa aaagactatt 1058101 taattcatga tgaaaaaatc atgctaatgc aggaaattgt tgaccgtcag ctggcggcag 1058161 tgccggattt gtaccgagta aaggatgaag tcagcattta tatcggcatt ccgttctgcc 1058221 cgacaaaatg cgcgtattgc acattccctg cgtacgctat ccaaggacag gcgggcagag 1058281 tcggctcatt cctatgggga ctgcattacg aaatgcagaa aatcggtgaa tggctgaagg 1058341 agcatgatgt taaggttaca accatttact ttggcggcgg gacgccgaca agcattacag 1058401 cggaggagat ggatctgctg tatgaagaaa tggtccgctc cttcccggat gtgaaaaaca 1058461 ttcgtgagat tacggtggag gccggtcgtc ctgacacgat tacagaagaa aaactcgccg 1058521 ttttaaacaa atatgacatt gatcggatca gcatcaatcc gcaatcctac gaaaacgaaa 1058581 cgctaaaggc gatcgggcgg caccatacgg ttgaagagac cattgagaaa tatcatctgt 1058641 cacgccagca cggcatgaat aatattaaca tggacttgat tattggtttg cctggggaag 1058701 gcgtgaagga gttcaggcac agtctttcag aaacagaaaa actgatgccg gaatccctta 1058761 ccgttcatac tctttcattt aaacgggcgt cagaaatgac gagaaacaag cataagtaca 1058821 aagttgccgg cagggaagag gtttctcaaa tgatggaaga cgcggtagcc tggacgaaag 1058881 agcatgggta cgtgccttat tatttatacc gccagaaaaa cattcttgga aaccttgaaa 1058941 acgtcggata ctctttgccg ggacaagaaa gcatctacaa cattatgatt atggaagagg 1059001 tgcagacgat tattggcatc ggctgcggcg ctgctagtaa atttattgat cgggatacag 1059061 ggaaaattac gcattttgcg aatccgaaag atccgaaatc gtacaatgag cgcttcgagc 1059121 actacacgga cgaaaaaatc aaatatttag agcagatttt tgaaaaaacg acaaagcagc 1059181 actgattaca gtgctgcttt ttttatccct gtttttttgc gggctgaacc tcaggcttcc 1059241 atttaaatac cttgttcagc aagcggtaaa ttcgttttga ttcctttgtg acaagcggtc 1059301 ccaaaatcgc cagaatgagg acatataatg cggcaaacgg ctttaatgtg gccgacagtc 1059361 cgccggctat cccgagattc gcaacgataa tcgaaaattc tccccgcgat acgatcgtca 1059421 gcccgatatt cgatgaagcc ttatgagaaa gccctgcgcg tcgtcctgcc accattccgg 1059481 cgataaaatt tcccagaatg gtcaaaatca ctgcacccaa cgcaagccaa accgcttcac 1059541 caagcgaaaa cggatcgatg ctgaggccga agctgaaaaa gaacatcgca ccgaagaagt 1059601 cgcgaaacgg aacaacgagg tgttcaatcc tatcggaatg ctctgtttct gaaaagacca 1059661 aaccgagcag cagcgcgccg attgcttctg ctacatgaat cgtctctgaa aaaccggcga 1059721 taaaaaagag tgctgcgaaa atgacgataa taaacacttc gtttgagcga atgtccaaca 1059781 gtttgttcaa cagcggcggg agttttcttg ctgcgataaa aaacagcagc atataaccga 1059841 aggcgatcaa aatggacaag agtgcactcc ctacggatgt cgcatcacct agtataaggc 1059901 cggaaacaac ggacagatat acggcaagga aaatatcttc aaacatgatg atgccgagaa 1059961 tcaattcggt ttccgggttg gcggttcttt ttaaatcaac gagcactttt gcgacaatcg 1060021 cacttgacga gattgtgatg acgcctgcga ggatgaggac ttccagaaag gaaaatccgg 1060081 tgataaaccc gtaaagcagt ccgaggctga agttaatcaa aatataaatc gtcccgccga 1060141 ccgcgattga ttttcctgat ttgattaact tcccgacaga gaattcgagt ccgagataga 1060201 agaggaggaa cagtacgccc attcgcccga aaaactcgat gatttcactg ctttgaataa 1060261 atgttagatc aataatcccc attttcggcg cgtgcggtcc aacaagcatt cccagcacaa 1060321 tcagaaacgg aataatcgaa aatttaattt tattggcgat cacactggcg attgccacaa 1060381 gcacaagtgc agttccgact tcaaatacaa gatggtccat cggggctcac acgccctctc 1060441 cagaaagaaa atcgtgaatc agtttcttca gatgctttct ctcacctgag aggacaaggg 1060501 tgtcattttc ttcaataatc gaatccgctc cgggatttag gagcttttcc tggttgtgtt 1060561 tgataatcgc aataacagtg acatcgtaat tctggcgaac atcaagctca ccgagtgtgc 1060621 gtccgatcga tttggcgcct ttttcgacct taaaccattc aataataaga tcgctgaagg 1060681 ccatttcgat ggactccaga gcttgcggtt tatagaccat gcccccgaga atagctgcaa 1060741 tttgccttgc ttcagaatca tccaatgaaa tatttgaaag aagctcatcc gggtcccggt 1060801 cattaaaccg gtaaatttcc cttcttccgt catcatgaat gataatcgtc attttttcgt 1060861 ggcttcttgt ttcgatttca aactttttgc cgatgcccgg cagatcgttt tctttaatat 1060921 tcaatgaaaa tccctccgaa tgtagtgttg gcagtatggg gtgagttaca aataaaactt 1060981 gagcaaatta tattcggagg taattagact ggtatttgac agggacggcc aaagcctttt 1061041 ccagcctgtt tatcagcggt tcgtcaagtg gtttgacaga gagctgcctg acagactgcg 1061101 ccagcgggct gtactctttg atcagctcag ccgggtgcat gctgcccggc gatggcgttt 1061161 ttgccgattg tgtttcctgc ggatatgaag acataggcac atagctgtca gtgcttgctt 1061221 caaactggga aggcagaacc acgtccgaag ggggaaagta caccataaat aaacttaaca 1061281 gaaaactgat cagcaattta tccatgttcc tttcctccct tctcatcaag atatcccttc 1061341 tttttcacta tataaaactt tatgtttcca ttcaaacaat atgcattttt cagtatctat 1061401 tgaccttgaa aaataaaaag gtttatttgg ggatggcggg gaatgtatag gagaaagaaa 1061461 aaagtaagcg catacatgga ggtgctttta atggagtttg ttcaatatgc atgtaatggg 1061521 gccgttgcag agattatcct gaatcggcct gatgcccatc acgccctgaa tgaacagatg 1061581 ctgtctgaat tgaaggaggc agtcgaaatg gcggctgcaa gcgaggcgct catcgttctc 1061641 ctgagaggaa gcgggaaagg cttttcggcc ggcggtgata tcaggatgat gacgtcagag 1061701 catgaccctg accaatttaa acggctgatg gatacgattg aggctgtcac cctgaattta 1061761 tatcagatga agaaagtgac aattgcagcc attcatggtg ctgctgcggg actgggcctg 1061821 agtttggcgc tttgtgcgga cattgtgctc gctgaaaaaa acgccgttct cgcgatgaat 1061881 tttatcggca ttgggcttgt tccggacggc ggaggacatt atttgctgaa gaaaagaatc 1061941 ggtgaagcaa aagcgaaaaa actgatttgg agcggaaaaa aactatctgc ctcggaagct 1062001 gccgatatgg ggcttcttga tgggacattt gccggagacc ctgccgaagg cgcaagaccc 1062061 attatcgaaa ccctgttggc ctcccctctt ttggcgatga tcgaaacgaa aggtattttt 1062121 caaagcctcc aaattgaaga actgaaaaaa gtgctatccc ttgagcgcag cgcccaagag 1062181 agaatgagaa ggaccaagga tcaccaagaa ggaatccgtg cctttttaga aaaacgggag 1062241 ccgaagtttc aagcgtaaca gatcagccgg aaagctgatc atctgtgaaa caaaatcagc 1062301 tttccggctg cattgactaa acgatgagta tgactatgaa gctctttttc ttttaagagg 1062361 gcttcaccat gcgtttttgc cgcttcttca tgttctgcct cgaattgctc gtttaccagc 1062421 gtgttccccg aaggatcaaa tacggtaagg aaataatcag ccatcaggtt tctcctccat 1062481 tttaaggttt atcagtcttt cttcatttat attctaaaaa ggaaatcaaa atcctttatt 1062541 atgctttatc caaaattagt atataatggg tcagggaagg aggagattca gtgcttacaa 1062601 ttgatcacgt aacgaagaca tttggagatt ataaagccgt tgacggattg gacttagata 1062661 ttccggaaca gcaaatgttc ggtctattag gcgcaaacgg agcgggaaaa acaacaacgt 1062721 ttcgcatgat cctaggatta ttaagcatta cggagggctc aatcagctgg aagggccgtc 1062781 ctgtgaatta tcatatcagc aacaaaatcg gttatttgcc ggaagagcgg ggcctttatc 1062841 cgaaaatgaa ggtaagggat cagctcgtct atcttgccag attaaaaggg atggagaagc 1062901 gagaggctgt aaaagagctc gggacatggc ttgaacgctt caatattaca gattacgaga 1062961 ataagaaggt ggaagagctt tcgaagggga atcagcagaa aatccaattc atttcggcag 1063021 ttttgcataa gccggagctc ctgattcttg atgaaccatt cagcggcttg gaccctgtca 1063081 atgttgagct gctaaaagag gccgtgatct cgctgaaaaa cagcggtgtt tctattttat 1063141 tttcaagcca tcggatggaa catgtggagg agctttgtga gaacctttgc atattgcaga 1063201 aaggaaaacc ggttgtacaa ggcaagctga aggagatcaa gcgttctttc ggtaaaaaga 1063261 atgttaccat tcactccgat gacgatctgc gctttttgca gtcccatgaa ggcattcttc 1063321 aatggaagga aacggcagac ggcgtcaagc tgcagattgc caatgaagac atttctcaag 1063381 agatttttgc gatgctccaa ggaaaagggt ttatcagaaa gtttgagctt gaagagccgt 1063441 cactgcatga tatttttata gaaaaggtgg gggccgtcta tgaataaatt ttggatcatg 1063501 ctttctcata catacaaaaa taagattatg gcaaaatcct ttattatttc gactgtcatc 1063561 acggtgctgc ttgttttagt tgtaacgaat ctggagtcga tcatttcttt gtttcaaggt 1063621 gacgatgcga aagaaaaaat cgccgttgtt gatgaaacaa acgaattata tccggttttt 1063681 tctaagcagc tgaaagcggt ggatacagac ggcgatcttg atgtgaagct gtcgaagcaa 1063741 tcggaggatg aggtcacaaa gcaagtcaaa gatgaatcac tcgatggcat gctcatcatc 1063801 aaacgagatg aaaaagggac catttcagga acatataaag cgttaacgat ttctgatgaa 1063861 agcacgtatc aaacactgca gcaggcgctg acgcaaacca aaacagctgt cggaacagcg 1063921 gagctcggcg tgtcgcagga aacgattagc agcctttatg cgcctgttac tgtggggcag 1063981 aaggcgctga aagaaggggc aaagtctgag gaagagcttg gccagacggt agggcttgtt 1064041 tacattatgc tgttcgtcat ttatttctcg gtgattatgt atgccagcat gatagcgatg 1064101 gaggtcgcaa ccgaaaaatc ttcgcgagtt atggaaatcc tgatctcaag tatgccgccg 1064161 atccagcaaa tgtttgcaaa gctgcttggt atcgggcttg tcgggatcac acagcttgct 1064221 attattatag gagccggctc tctgtcgctt aagctgaacc aaaagagcga aacggcttca 1064281 tctgtcggcg gattccttaa tttgaccgac gtatctgcaa ccactgtcat ctatgctgtc 1064341 attttctttt tgctcggata ctttttgtac gcgacacttg ccgcgtttct cggcagtgtc 1064401 gtcagcagaa tagaggacgt gcagcaaacg atcacgccga tgacgctttt ggttgtcgcc 1064461 ggttttatga tcgcgatgtt cggtttgaat gcgcctgacg caggatttat tacggtaact 1064521 tcgtttattc cgttctttac gccaatgatt atgttcctgc gcgtcggcat gcttgatatt 1064581 ccgttctggc aggcggctgt cggaatcgga atcacactgc tcaccattgt catactggcc 1064641 gttatcggcg ccagaattta taaaggcggt gtattaattt acggcaattc aagcgcgttc 1064701 aaagcgatca aacaagcgct acgtttagcg aaaaactgat tggaaaacag cctggggatt 1064761 ctcaggctgt ttctttattg acagaacgtg cattcgcaag aattcggtgc taaaataagg 1064821 gtacttcatc ctggaaagga gcagaatgtt gactgatcta acctttattc atgcggcaga 1064881 tcttcatctt gacagcccgt tttacgggat atcgcatctg ccggagccga tttttgcccg 1064941 gattaaagaa agcacgtttg caagcgtgag acatatgata gacgccgcag tgagagagca 1065001 cgttgatttc attttgcttg cgggagatct gtttgatgaa gccaatcgaa gcttaaaggc 1065061 tcagctcttt ttgaaaaaac agtttgaaag actcagagag tgcggaattt cggtatacgt 1065121 catctttggg aatcacgatc atcttggcgg ggagtggacg ccgattgaat ggcctgagaa 1065181 tgtccatatt ttttcgtccg ctgttccaga agaaaaatcg ttttttaaag aaggcaggcg 1065241 catagcaagc atttacggct tcagctatca agccagagca ttgatggaaa accaagccgc 1065301 ccgctatcgg agatcaactg acgcaccgtt tcatatcggc atgctccacg gcacgctgtc 1065361 aggatctgaa ggacacgatc cgtattgccc gtttacacat gacgacctcg tgaaaagcgg 1065421 gatggattat tgggcgcttg gccatataca taaacgccag gttctatctg ccgagcatcc 1065481 ggcagtcatt tacccgggaa acacgcaagc acgccatata aaggagacgg gagataaagg 1065541 ctattatctc gttcatgtga caaacggaga tatatcttat gaatttcaga gagcgcatga 1065601 tgtcctgtgg gaaaaagcgg cggttgatgt gacggaggca aagaatatga cagccctctt 1065661 ccaaatggtg gaggacacgt tttcgaagct gcggaaaaag gggagccctg tttgtgtaag 1065721 gcttgtttta caagggacgg cgccggaatg gctgctggag gcgccaaaag gcaccttgga 1065781 tgagtttctt gaagctcttc aggaacaaga agcggaagag gaacgtttcg tttggcctct 1065841 tagattggac gatgagacag aaaacgaagc aaacctaaca aaccttgatc ctttttttgg 1065901 cggtttattt gaagacattg atcgcagcga tctgtcagac gtgctggaag ggcttgagcg 1065961 gcatccagtg tatagaaggc acgcggaccg gtttagccaa gaggaggtaa aggaaataaa 1066021 agagcaggca cagataatat tgaaaagaca gcttaaggtg cttgatacat gaggcggtga 1066081 cagctttgcg aattatatct ttacatatct accaatacgg aaaattttcc aatcggacct 1066141 ttgacttttc cgcctctcct gtccaagtca tctacggatt aaatgaggca ggaaaaacga 1066201 cgatgatgtc attcattgaa agcatgctgt tcggttttcc gaaaacgaaa aagtatgaac 1066261 cgaaaacagg cggtgtctac ggcggtgttc ttgaagctga acatcctgag tatggggtgc 1066321 tgaagatcga acggacgaaa gggactgccg aaaaactaag cgtgtacaca gaaaagggcg 1066381 aagtaaagca gggagatgtt ttaaagcagc tgttccaggg cacagacagg tcgttgtaca 1066441 aagccatata ttcgttcgac gtattcgggc tgcaggaaat tcacgccttt aatcgggaca 1066501 agatagggga atttttgctc ttttccagct tgtttggtgc tgaagccgta tcaaagcttg 1066561 attcaaggct gacgaaggaa agcgaaaggc tctataaacc aaatgggcga aaccctcaat 1066621 tgaatcagga gctggaaacg cttaagcagc tggcagttaa gctaaaacag gctgaagcag 1066681 aggaagcggg ctatcatcag cttctcgagg aaaaacgaac gcttgaagcc cgccttgcag 1066741 ccgcggaaac cgaattgaaa gagacggcgg gacatatccg aatgattgag ggagcgattg 1066801 agcgaaagcc gctgctaaat gaaaaagcga cactcgaaca ggtgattgca gaatttccgg 1066861 aacacgcagg acaatttcct gctgacggac tgcatcagct ggaaaaatat gaatcccatc 1066921 ttcacccgaa atcagcacag cttgaggcgc ttcgggtgaa gatggcggag ttggacaaac 1066981 agaggcaaaa gcttatcccc gataaagaac tattggcgaa agaaacgctg atacaagagc 1067041 tttcggcagc gtttcatatg taccaatcct ggggagaaca gctggcagcc attcaggcac 1067101 agctgcgcca gacgtctgcg cagacagcgg cagggctgga acagctcaat aaaacggatg 1067161 aaaatgagct cctgaatatg aacacctcat atgattatga atggcagctt cagcaagcgg 1067221 tgcagcaata tgtacaggca agagacagaa aacggcagct tgacgagacg tttgaacttg 1067281 cccggcaaga gctggaagac gcggaaaagg ccgttcgtgc cgcttcgtcc gcgattcttg 1067341 aaaacagcca aagaaaagat aaagaagcag ctcttagagc atatgatgaa acacaggggc 1067401 agcaccaaga gcaagcgaag ctcagagaac agctaacgtt ttttgaaaga cagcaggcta 1067461 aacagaaaaa gactgtcatt gcagctggta tgttgttcat cgttctcttt tctctgctgc 1067521 agcaatggat tcccgccata agtttcggcg ctgcacttat tgtgtattgg cttgtttcag 1067581 gaaagtcgtc ttctcgaaac agccgagaga caagacagcc catgacggat atttcaccag 1067641 cagaagctga aatgcttaga gaagcgttat gggaggatga ccgcaataag cagcaccttc 1067701 tcacacagcg tgcagcgctc cagcaaaaag aggcggcgta tgaaagggtc atccagcagt 1067761 ttgaacagtg ggaagccgaa atggcgccgt cctttacaca ggttgagcgt tttatgaatg 1067821 agctcggatt taaggaagat ccatcatttt tgcttgatgc atacagctta atgaaggatg 1067881 ttaaaaaaga agtgaagaaa aagcatgagc tgaccataga agcaggcagg ctgaaaaagc 1067941 accggagaac attcgaagaa cgcgtcagta tgcttcttcc cgtgaatcag agtcaggata 1068001 tctccatttc ggacgccctt cacacattgc ggaaaaacat tgaacgtgaa aaagaaattg 1068061 agaagcaaaa aaaggaaatt gaaacagata ttcattatac aaaggaacag atgcttgaac 1068121 ttgagcaaga aatacagtat ttccacgcac agattgaaca gttatttgcc gcggctgctg 1068181 caaaagacag agatgcgttt tttgccatag ccgccatcag caggcaattg aaggatacgg 1068241 agaacaagct tcatcacgta aacgcacagc ttcaaggcgg gtacccggag gaacttgaac 1068301 tggcggattc caatacgctt tctgaattga aagataagca atttgttgag aatgaaagaa 1068361 aagagcggct gactgaggag atcgagcagc tccgcagcca aatcgcactg ctctcagtca 1068421 aacaggaaca attagaggct tcgggaatgg tctcagacct caagcttcaa accgaaatgc 1068481 aaaaagaacg tgtgaaagaa acggctaaaa aatgggcctc catacaaatg gtcaaacagg 1068541 tgatcagaaa caaattggag cggcataaaa aaatcgagct tccgcgcctt ctggagacgg 1068601 caggagaatt tttccgtcct ctgactgacg gaaactacca aaccatttat ttttccgaaa 1068661 cggatgattc gatcatggtt atgcatcgcg atggcactgt ctatcatgcg gaagagctgt 1068721 cacaagggac gtgtgaacag ctgtatacag cgatccgctt tgctttggcc gttacgcgcc 1068781 agggtgagtc aaagcttccg ttccagcttg acgacagttt tgttcatttt gatcaggaaa 1068841 ggctgaaacg tgtattacat gttctgtatg atttatctga aggcggtagg cagattttgt 1068901 attttacatg ccatgagcac gtaaaagatg catttcatag cagccaaatc atccatttgg 1068961 tgtcataaaa gaggttctat agctgaaaat cggtatgtga tatactggta ttatgtaaga 1069021 tacggaggga gctttaatag aatggctaaa gggattatgc tacatgaggt tggcgaacag 1069081 gtggaccagt atctattgat taaatcctcg acgaaaggga ttgcaagcaa tggaaaaccg 1069141 tttctgacgc tgatgctgca agaccagtca ggcgatattg aagcgaagct gtgggatgcc 1069201 aagcaaagtg atgaagtgac ctatgcgccg cagacgattg tcaaggtcgt cggcgatgtt 1069261 caccattatc gcggacgcac ccagctgaag ctaagaaata tcagaccggt aagcgagcaa 1069321 gaaaacgtca atattgatga ttttttagaa accgcgccga ttccgaaaaa tgaaatgatg 1069381 gataccatca ctcaatatat atttgaaatg aaaaatccga atatccagcg aatcacaagg 1069441 tttttggtta aaaaacacga agctgagttt atggattatc cggcggctac gaaaaaccac 1069501 catgagtttg tctcaggttt ggcgtatcat gttgtctcta tgctgaacct ggcgaaagca 1069561 atagcagatt tatatccttc tcttgatcgt gatctgcttt acgccggtgt tatcctgcat 1069621 gatcttggaa aagtgaagga gctgtccggc cctgtttcca cttcatatac ggttgaaggc 1069681 aatttgctcg gccatatttc catcatggtg acagagcttt caaaagcggc tgaggagctt 1069741 caaatcgatt ctgaagaggt gttaattctt cagcatttga ttttgagtca ccacggcaaa 1069801 gcagaatggg gcagcccgaa accgcctatg gtgaaagaag cggaaattct tcactatata 1069861 gacaatctgg atgcaaaaat gaatatgatg gacagagcgc ttgagcgcgt gaagccgggc 1069921 gagtatactg aacgtgtatt tgcactggaa aaccgttcct tttataaacc gacatttcat 1069981 aaataactta aaaaggactg atgctgacat attcagctca gtcctttttg atgcgtcttt 1070041 cccgcacata actcgtctca ttcccgcata tggttaagaa taaagaatct atgcaaaggg 1070101 ggaggagccc gtgttatttt ttccgtggtg ggtgtatctt tgtattgtag gcatcatttt 1070161 cagcgcatat aaacttgtgg cggcagccaa agaggaagaa aaagtagacc aggcttttat 1070221 tgaaaaagaa ggacagattt atatggagag gatggaaaag gagcgagaac gccgcagttc 1070281 tcagcagcat gaagaagaaa atcaaaacca ttccatcgca taaaaaaagc tgtgcggctc 1070341 aatgagccgc acagcttttt ttattattta gaattgcttg aagatgaaga agtgctgttg 1070401 cttgttgaag atgtattaaa tgtgtctttc agatctttat cttttacttc gatgtcagcc 1070461 ttcttcatga ctttttgaac agcttcctga acagctgcgt tgtcatttaa tttttgttca 1070521 agcacttcag atttcagttc ttttttcata tcatcatatt tgccgcgttc ttctgtcttt 1070581 ttaatgatat ggtagccgta ttgcgttttg acaggatcac tgacttcacc tgtttttaat 1070641 ttgaatgcag ctttgctgaa tgtttcgtcc atttggcctt cttttgcgaa ccagccaaga 1070701 tccccgcctt ttgaagcaga gctgtctgtt gagtattctt tcgcaaggtc ttcaaacttc 1070761 tcgccttttt tcagcttttt ctctacttct tcagctgtct ttttatcagc aacaaggatg 1070821 tggcttgcac ggattttgcc ttttaagcct tcccagtact ctttgatatc ggcgtctgtt 1070881 actttgatgt tatctttagc cgctttttgt gtcagcaatt catattttac ttgttctttc 1070941 aggtaatctt tgccatattg cttttcgagg gcagtatatt gatcgccaag ctgcgttttg 1071001 tattctttca gcttgttgtc aatttcttta tccgaaactt tatacttctt gtccaatact 1071061 ttttcttgca ctagctgtgt cagtacgctt gcgccagctg ttttcttcat gtttgtgtaa 1071121 agctcgcctt ttgtgacatc gcctgcgtct gtttttgcga taacttcttt gtcgccgctg 1071181 ctgcaagcac tgagagcgag gatgcttgta gcagtgatag ctgctattgc gattttcttc 1071241 attgttttca aacactccta atcattccaa attaaattac ctatgcgtat cataacatat 1071301 tgtggctttc tgtaaaaaga ttttaaataa agggcattcg tctagtcaaa cttttgctga 1071361 tgacatactt atatattgat caagaaaagg aggtatgtaa catgagcgga ggatactcta 1071421 acggattcgc gttgctcgta gtactgttca ttttgcttat catcgtaggt gcagcttaca 1071481 tctactaagc agcccgagga tcgcttgcaa cataagcgat cctttatttt cactagcgcc 1071541 taatcgtttc aaacatgaat tgcataacat gtaattggta aataaagctt attacaggag 1071601 gtgctattta agatgggtga agtatttgca ggcggattcg ctttattggt tgtgttattt 1071661 attttattga ttatcatcgg cgcttcttgg ctgtactaat caacataaaa aagcatagct 1071721 gcttaatcag cagctatgct ttctttcgta tttacactgt aaaggagatc tccacaaacg 1071781 aagagatcag taaaattaat atagatacat taataaatcg gaatacctta tcttgccgct 1071841 cttcaggaat ctctctgaca aggcataatg tattggtgag cctgtttatg aaatataaaa 1071901 taaacacggc agccacgata aaatagaata aaatgatggg agattccccc tctctctgaa 1071961 ctgtcccata ttacattacc aaatatttat taaaaaagat agaatgcaaa ttgaaaaatc 1072021 gccaccagca ccagggtttg actacttttc aacaagaata tccaagccgt cagcttcctg 1072081 atcaataaaa gcggttttcg gtgcttttat cagcttgaga gccagcagga aatcaggcag 1072141 acagtagccg gcgtgaatgc ccgagatcat gcaaaaataa tgagcgtgat tcggaaatgc 1072201 cagtgctgcg taaaacaata ccggtgtaat cagcaagaac gggctgacga gtgaaatcag 1072261 cattgttgtt tttggtatac gtttccatgt gcgcatgcgc aatatgtaaa actttttttc 1072321 tatttttctt tttttgcaga tgattggcag gacatggatg actttatgta caaataaaat 1072381 aacgacgagc aaaccgccga ataaagatac atattcatcg cttaagcttg tgccaggccg 1072441 cagcagctca aaagctaaaa aggtagatat aaaaaccaaa atcataaaac atacagcagt 1072501 taatattatg cgaacggcgc cataatcctt catgagattt atggtcttcc agcaattcat 1072561 caaagtcatc cttccataca tcttgaatag aatctcaaaa taatttactc ctcccaagag 1072621 aaaaaatcaa tgctttttta agaaaaaata tcatccggca ggtatttttt tgaaacaagc 1072681 aaacaaactg cgaaatatgg ggttagaact ttcttctcag tgaattatca gctaaaataa 1072741 gattaaagat agaaagaagt ggtgtggatg gattcgatgg atcatcgcat tgagcgatta 1072801 gaatattaca tacaattatt agtgaaaaca gtagatatgg acaggtaccc cttctatgcg 1072861 cttctcattg ataaagggct gagcaaggaa gaaggggaag cggttatgag gatatgcgac 1072921 gaattgtcgg aagagctggc aacacaaaaa gcgcaaggat ttgtaacctt tgataagctc 1072981 cttgcgcttt ttgccggaca gctgaatgaa aaattagatg ttcatgaaac aatttttgcc 1073041 ctgtatgagc aggggcttta tcaagagctg atggaagtct ttatcgacat catgaagcat 1073101 tttgattaac tgtttacagg ttcgagctct tcagccggtt catccgccgc actgtccttt 1073161 gcttttttct tcaattttcc gtttacgctt tcaaagtcat tgtcaatatt ggtgagtgac 1073221 gtttcgaaaa tttccataaa atcatcgccg tagatatggc gtatcataca catcatttct 1073281 gccacttcag gaaattttcc gaataaatga tataaaggct gtgacccttt aaaaacagcg 1073341 ttgcgtgtcg gatcaaattc ctcaagcaag ctccagaata cctcggtacc ttcctcagtc 1073401 aattggacat atgtgttccg tttatcattc agccgtttgg agaaccttaa atatccccgt 1073461 tcttccagct tttttgaaaa gttgaatgcg gttgatacgt gcatgacccc gaatttcgcg 1073521 atttcagaaa tggaagctcc attcaattga tacgcaatcc ataaaatatg atgctcatta 1073581 atattcaggt catacggttt gagccattgc tgccaatcct tctcgatcga tttccaaaga 1073641 gccttgctaa gctgagccat tttctgggtg aaaaccagag cttctttcac atcatagggc 1073701 ggttccactc gattcattac gtcacctgct tctctttttc tttttctcta ttatgccaat 1073761 aaaataaaga ttaataaaga tgaaaatgta agaatttttt aataaattca caaaccattg 1073821 cgacgaaagg gtttttcggc caaaaaaaat acgggtccaa ttttggcccg catttttttc 1073881 ttttgaatag gatattagtt ttgtaaggtt ttctccagct gtctgatttt ctcttcgata 1073941 tcggcaattt ctttttgcag atcctgctgg tgaggcttga tctcttcctg ccatttttta 1074001 attgatgttt ggagctcgcc gcccacgtct ttaataacat ccgtgctttc ttttgccgct 1074061 ttgatcagct ggtcttttaa tgcaagcccg tctgacttta agcgtttgat tgtttcttca 1074121 aaagaatcat aattggtttt cattttttca cgcagctgct ttcctgagga aggtgcagta 1074181 agaagaaccg ctgctcctcc gatgatgccg cctacgaata gtcctgttaa tagagaacgt 1074241 ccgctcgcca ttacaatcac cccgtctttt tcttcaaaat aggattcatt cagcattttt 1074301 catttttgtt gaaagcctga acttctatac atagcttgct ttattttagc atatttttta 1074361 agtgaaaagg agggagaagg ttgtctgtct ttttgattgt attatcctgc atcacccttg 1074421 ccttcgcttc aggcgctgtt tactatatca aacttctcag ccaggctgct tcttatccgc 1074481 ccaagagggt tatccggcag aaagcgcttg tttgttcaac cggaaccgcc tttacactat 1074541 gtcttatctt tttcacaaaa ctcctcgctt aaaacatgct gacatgctgc gggcgctctg 1074601 ttcaaaaaaa cctctcccgg aagcggaaga ggttttgtgt gacaattatt tagcagcttc 1074661 cataaagctt gaacgcctta aaatggtttg cacaatcgga taaataatga tcattgagat 1074721 tgtattcagc acagcggccg gcagaacaac agccgcgaac aatgcggcga aaccgcccgg 1074781 taaaccgacg atcaataaag ctgacgatag aaacacaatt cctgataaga tggtcccgat 1074841 cactgtcagc acagcggctg cacctgtttt ccggctcttt ctgaacaaga gaaacaggga 1074901 gaagaacaga aacgctgata cgggtttatc aatgatgtta gggatctgtc cggctggaaa 1074961 cgcggttgta agcgcggaaa tgattccggt cacgatcccg atgacgagta cattttgcac 1075021 ccgcgggaac agcagaatgc ccatgaacat catgatcagc atcatatctg gtttcatgcc 1075081 gcctaaaaag ggcggaataa tggaatgaag cgctgcgccg attgcggcaa acagagccat 1075141 aatgactaac tcttttgttt tcataactat gctctcctct gctaagcttt ttgccctcca 1075201 ataatatgct catcatttat tgcgaaggct ttacagaatg tgttatgcaa acagtatacc 1075261 aaacggacgg tttgcatagc cagacttttt actcattttc ctgctggaat ttcttcatga 1075321 acgcagctaa tttttcacag tcttcgagag agaccgcgtt ataaatagaa gcgcggcagc 1075381 ctcccaccga acggtgtccg ccaaggccga tcatcttcgc atcttttgct ttctgaacga 1075441 atgttttcgt taattcgtca tcccgaagcg tgaatgtgac attcatgcgt gagcggctgt 1075501 cttttctggc atgtccttta tagaagccgt tgctttcatc aatacagctg tagagaacct 1075561 gcgctttttg ttcattgcgc tgttcaacag cttccacacc gccgttttcc ttgagccatt 1075621 ccagaacgag gctcagcata taaatcgcaa atgtcggcgg agtgttgtag agtgaatccg 1075681 ctttgacatg cgtggaatat ttcaagattt ttgggacgtt cgcattttca ttttgcagcc 1075741 agcttttttt catgatgact acagtcacgc cggaagggcc gaggttcttt tgggcgcctc 1075801 cgtagatcac atcaaatttg gacacatcga tttttctgct taaaatatcg ctggacatgt 1075861 cggctacgag cggaattgga gaattcggaa actcctgcca ctgagtgccg aaaattgtat 1075921 tgttggatgt gatatgtaaa tatgcgccgt cttttacatc cgtaaggtca acctctggaa 1075981 tataactgta attgtctgtt tcacttgtag cggtgataga cgtgttcccg aacagtttcg 1076041 tttctgccag tgctttttca gaccaagcgc cggtcatcac aaaatgtgcg gttttttcag 1076101 gtgttaaaaa gttcatcgga agcattgaga attgaaggct tgccccgcct tgaagaaaca 1076161 agatatcgta atcttccgga atgcccatca gttcgattaa gaggcttttc gctttttggt 1076221 gcaccgcttc atactctttg ctgcggtggg aaagctccat aacagacatg ccggattcgt 1076281 taaaatcaat aaattctttc tgtgcttttt gcagaacttc cagtggcagc gctgcaggac 1076341 ctgcgttaaa attcgttgta cgttccatta tgatctctcc ctgttttcca cgttaatgta 1076401 taaaataata caattatcct atcacaaaaa ttcagttttt tgataaaaaa ttagaattat 1076461 caaaagaaat tgacggatgt ttgcgaaatg ttcacaaaat aaaataacct catcttatga 1076521 tgaggccagg cgttttgcga tagaggaaga gatgttctgc agatcctccg gtttataatc 1076581 atcagcatgc gttttccaaa ccgctccgaa tccatctcct tttccgtagc gagggataat 1076641 atgcatatgg tagtggaaca cagattgtcc agctttttcg ccgttattgt tcagcgtatt 1076701 taagccgatc ggttcaaatt catcccggat agcgcgggcg atttttggaa cagcatggaa 1076761 atattgtttt gctaattcat ctgtaaattc atatacattc tcaatatgtg ttttcggaat 1076821 gacaagcgta tggccttttg tcacttggct gatatcaaga aaggcaagta catgttcatc 1076881 ttcatacacc ttcgctgatg gaatgtcgcc ggcaataatt ttacaaaaga tacaattctc 1076941 tgcacaatgc atgagggttc ctccttatga aattgtttag tatgtataca ttcatcgtac 1077001 cacagaaatg cagaaaatag aaaacaggat gaacggcgag cgttcaccct gaatgcagag 1077061 gaagagctta tatgaagaaa atgtgttatg cctttggtaa gcacctcatt tgtcaataaa 1077121 atgaagactt gtttaatgcc taacgattcc tgcgataaac acctcatttg acaatttgct 1077181 tcatacatga agaattcatc aattcagtga agagaaatgg tttgagcatt ggacatgttt 1077241 attttctatc caactgtttc taagacgtct ttgacaaaca cctcattttt cagttgatat 1077301 gcttttcctc tacaactttt atgatgtcca gaaccctgtc tctttatgac agcaaattca 1077361 tcatttgtta aaagggaatt gtttcaaatc aggccttgtt tttggtacta tgaagaaaaa 1077421 cactataagg ggagaaacta tgtctctgct atcggtaaaa gacttgaccg gcggatatac 1077481 aaggaatccg gttttaaaaa acgtatcatt cacccttgaa ccgaatcaaa ttgtcggctt 1077541 aatcgggctg aatggtgctg gtaaaagtac aacaatcaga cacatcatcg ggctgatgga 1077601 cccgcataaa ggttcaatcg aattaaacgg taaaacgttt gctgaggatc cggaaggcta 1077661 ccgttcacaa tttacctata tacctgaaac acctgtttta tacgaagaat tgacgctgat 1077721 ggagcatctt gaactaacag ccatggcata tggactgtca aaagaaacga tggagaaaag 1077781 gctgcctccg ctactaaagg aattccgaat ggaaaagagg ctgaagtggt tcccggccca 1077841 tttttctaaa ggaatgaagc agaaggttat gattatgtgc gcatttttgg cagagcctgc 1077901 gctctacatt attgatgagc cttttctagg gcttgatccg cttgccatta acgcgctgct 1077961 tgaacggatg aatgaagcga aaaaaggcgg ggcgagcgtg ctgatgtcaa cacacatttt 1078021 ggcaacggca gaacgctatt gcgattcgtt tattatttta cataacggcg aggtgcgggc 1078081 gcgcggcacg ctgtcagagc tcagagagca gtttggaatg aaggacgcgg cgctggacga 1078141 tttgtatctt gagcttacaa aggaagacgc tggccatgaa taatatgctt gatatttggc 1078201 agtcgcggct gcaggagcat atcaaagaaa caagaacata catgaaatat atgctcaacg 1078261 atcacctcgt cattgttttg attttttttc tagcgggcgc tgcaagctgg tacagcaaat 1078321 ggatacggga cattcccgct cactttccgt ccttttgggt gatggccgtg ctgttttcgc 1078381 tcgtattgac aagctcttat gtgcgaacgc ttttgaagga ggctgacctt gttttcttat 1078441 tgcctcttga agcaaaaatg gagccttact tgaagcaggc gtttgtctac agctatgtgt 1078501 ctcagctgtt tccgctgatt gcgctgagca tcgttgcgat gccgctttat ttcgcagtca 1078561 ctccgggagc ttcgctcgta tcgtatgccg cggtctttgt ccaactgttg ctgctgaaag 1078621 cgtggaatca ggtaatggaa tggcgaacga ctttccaaaa cgaccgcagc atgaaacgga 1078681 tggacgtcat cattcgcttt gcggcgaata cactcgttct ttattttgtt ttccaatctg 1078741 tttatatgta tgcgcttctc gtctatgtca ttatggctgt tctttatctg tatatgtctt 1078801 ccgcagcaaa acggaaaaca tttaaatggg agagccatat tgagtccgaa ttgagacgaa 1078861 agcagcgttt ctatcggatt gccaacctgt ttactgatgt gccgcatttg cgaaagcaag 1078921 ccaaacgcag agcttatctc gactttttgc tgcggcttgt gccgtttgaa cagcgcaaaa 1078981 catttgccta tatgttcacc cgcgcctttt tgcgttcgag cgattatttg ggcattcttg 1079041 tcagattaac gatcgttttc gcgctgatca ttatgtatgt ctcagccagc ccgctgattg 1079101 ccgcggtttt gactgtgttt gccattttca ttacgggcat tcagcttctg ccgctcttcg 1079161 gtcactttga ccatctggcg cttcaagagc tgtaccctgt gcaaaaagaa acaaagctga 1079221 aaagctattt ctctctatta aaaactgcac ttagtattca agcgctgctg atgtctgttg 1079281 catctgccta tgcagccggc ttgaccggtt ttctgtacgc gctgatcggt tctgccgttc 1079341 tgatttttgt tgttttgcct gcttatatga cgaccaggct gaaaaagcac ggaaagctgt 1079401 gaactgaaaa gaggtaatca aatgacagat aatcagctgc tgatgcagga agctttggaa 1079461 tggaaaatgc attttttgcg aaaggattcc atgtttgaac gcttttcgaa gcgtgtccag 1079521 acgaaggtga atgaacggat tcctgaaaaa atccatacgg tcgtcaccga gagtgtgaaa 1079581 aaaatggtag aagcgacaat ggccggctct aatatcatca cctataaaaa ggatacaagt 1079641 gcactgtcgc tcagtgaaaa aaacgaattg gcgaaaaaaa cgattgtttc ttatcaaaaa 1079701 gtggcagctg ctgagggagt cggcaccgga gcgggcggca tttttttaag cattgctgat 1079761 tttccgctgc tgctttcaat taagatgaag tgtttattta ccttgtcttc catttacggc 1079821 tttgatgtca aggatgcaca agaaaggata tttttgctgc tcgtgtttca gcttgcgttt 1079881 tcgagtgatg atggccgtaa gtcgcttttt tctgtcatcg aaaattggga gacggagaaa 1079941 aagagcatcg actggagagt gttccagcag gaatatcgcg attatatcga cgtcgtgaag 1080001 ctttttcagc ttttgccggg cgtaggagcg gcagtcggcg gaattgccaa ttataagctg 1080061 cttgctcagc ttggagaaac ggcaagacat gtttttcatc tgaggatatt aaaggaaaca 1080121 gccggagaat aaacactccg gctgtttttt tatagctgat gataggtgat cgcagcgccg 1080181 gcaaggacct tggccgctgt cagcatggct ttttcgttga tatcaaattt cggatggtgg 1080241 tgggaataga ctcgctctgg ctgttcggga gcggcgcctg taaagaaaaa agtgcccttc 1080301 acgttttgta agtaataagc aaaatcctcg ccgcccattt gtggttcacc gtcaatgacc 1080361 tgctgaacgc cctcggtatt ctttgcggtg ctcaccaagt ggttcgtttc tgcaggatgg 1080421 ttcacaaccg ctggataacc ctgttcatag gtgtactcat aggacgcgcc gtgcatgctg 1080481 catattcctt ttacaaccgc ttcaatttct ttctccagaa tgtcccggac attttcatca 1080541 aaagaacgcg ctgtgccgat gagtactgct tggtctgcga tgacattaaa cggattgtcg 1080601 gcgatgaagg agcctgtcga aatgacggcg gattgaatcg gattgacttt gcggctgaca 1080661 atgtgctgca aagaggaaac gatttgcgaa ccgattagga cggcgtcttt agtatcatgc 1080721 ggatgagcgc cgtggccgcc ctttccgaag actttaatcg taaatcggtc tgccgccgcc 1080781 attacggcgc cggggcggca gagaatagtt ccgagcggct cagttgccca aagatgagtg 1080841 ccgaatatca catccgtgtt ttcgagacat ccgtcatcaa tcattggctt tgcgcctcca 1080901 ggataatatt cttctgcatg ctggtggatc atcacaaatg ttcccttcag ttcatgtctg 1080961 ttttggtgaa ggaccttggc cactgcgaga agagctgcgg tgtggccgtc gtggccgcat 1081021 gcatgcatga caccaggcac tttggaggcg taagggacat ctttttcatc ttgaatgggg 1081081 agagcgtcaa agtcggccct caaagcgact gtagggccgg gttcgcttcc ttctatattt 1081141 gctaaaaccc ctctaccgcc aacgtttgtg cggattggga ctcctaacga ttcataatag 1081201 gaagcaataa atgcggcggt tttttcttct tgaaatgaga gctcaggata catatgaaaa 1081261 tggcgcctga tctcaaccat ttcttcaaaa cagccgtcga gctgtttgtt tatctctttc 1081321 tgcagtgtgg atatggacaa agccgcttcc cccttttcta tgcttttcca tgattgtata 1081381 gaaaaagtct gaatatttca actcatgctg ttttaaagca tcatcacagc tgcgagggtt 1081441 gtcaccaaaa ggccaatcgc gacgggaatg aagttttttc tggcaagctc aaaaggatca 1081501 actttgcaaa tggccgcggc gggaatcaaa gcccatggga ccagtgttcc tccgcccacc 1081561 cagatggcag agatttgtcc gagcgcggtc agaatagcgg gatcggcatg gagagcggac 1081621 gaaaagagct ttgcgatgga gccggcgaga gaaatgccag aaaatcctga gccgtcaagg 1081681 cctgttatgg ctccagcggc agttaatgca gtggcggcaa gctcctttga cataggcatc 1081741 atatgggata aagcaatgcc aagatcgttg acaatgccgt gggaaccttt agggagtgaa 1081801 gtgcccagta tgctttcata gcctgagtcg ccaagataaa agaaagcggc aatcgggatg 1081861 acggggccga aaaccttaaa accgaactta aatccgtcaa taaaatagcc ggtgattttt 1081921 tcaagccctt tatgcttata cacgaaaaaa tgaacggtaa agaggataca aattgcagac 1081981 ccgccaatta acgcggttgc atcatttcct tgtaggttaa acaagagcat gcaggcgata 1082041 tctgcaagaa aggcaagcgg aatcaaaaaa gccagtatgg accgcaggcg ttttggcaag 1082101 tacagcgagt tgtcttgttc gccggaaaga acgggggaaa aagaagtggg atgctcctgt 1082161 tttttgcgtt cgcgctgaat catgataaag gcagcagttg ttgttgtcac acccataatc 1082221 agcacaagcg gaatactggc cgagacgaca tcaccgactg gaatgcctgc tgcatccgca 1082281 gtcagctttg gcgccgcctg aatgacaaag tctcctgaca gggcaaaacc gtgtccgaat 1082341 aagttcatgg ccatggccgc ggcaagaggc gtcaaaccgg cacgtgcggc tgcggggagc 1082401 aggacggcgc cgatcaaagc gacacccgga gaaggccaga agaatagaga aatggcgaac 1082461 atcaggcctc caatcagcca ataggcagtc acaggccctc tcacaaggct tgcaaaggga 1082521 gaaatcatcg cttcatttat ccctgttttt gttaacaaat cactcattga aacgataaag 1082581 caaatgatga aaatcgtggg cagcagttcg ccggccgcat agataaagct gtggaataaa 1082641 ctgctgacag aagctgaaag tgaatggctg gcccatagcg atatgataaa aatgccgaat 1082701 agagaaataa atgtcgtgtc ttttctcagc agcataaata ggataattgc accgataaaa 1082761 aacacataca gaacatggac aggcaaaatc ccgacttcca tcatcgatca ctccttccgc 1082821 ttacagatta ttcataggcg ggcggaaggt gccgggacag aggggagggt tatgatggaa 1082881 gatgaacatt gatctgtttc agctgctcaa tcagatgatg ccttaatcct ctattcgctt 1082941 tttgcagatg ttttgggaag cattcaggag aaaaaatgac gcacccttca gcaagccagt 1083001 tttttctata ggcgatgatg ctttccgatg gctctatatg agttatcctc gtgctgcatc 1083061 tcgtactcat caaatccgaa ctgaaaaccg cagcacgggc agatttcatg agaatgattg 1083121 ccttcatgat catatggcgg ttcagccaat ccttaaaccc gcagactggg caagtatgct 1083181 tcattttgct ttcctcccaa taaaataagc tgccggacat gccggcagct attcgacagc 1083241 gaaatatgtg gtgacatagg aaggccggga gaagatcgac gttgtgtcaa ttccggcaga 1083301 tgtatcgcgt tttttgtggg cttctttgta agaaccggac tgctgccagt cttgaaaggc 1083361 gctttccgtt tcccacaagg tcagaatgac ataggtgtca ctgtcaagcg gacggagcac 1083421 tcgaattgct tcaaagccag gctcgttttc gacttttccc gctctgtttt taaatctgtt 1083481 ttcaaacagc ggacgccctt cctgagtaac ggcaatattg ttcaatactg caaaaccggg 1083541 atgtttgatc tctccgactt ggtcaatgac ttcataagcg tgtggtgcct ggaaaacggt 1083601 atctccgttt gtttcatgaa ttaaaatggc gttttcctgc ccctgcatca aaaggatatt 1083661 ttctgaggga tgcttctgta cgatcgtttt taaaaaatcg gctgtcccat atgtaatata 1083721 aaccttcata tcagccacct cctgcttgct agtatatcaa aacaatggta taagtttcta 1083781 ttggcgagtg cttcgaacat aattccaaac aatttttccc atactacctt tagaaaggcg 1083841 aggtgagttc atgtttaaga taaagaaaaa gaaacttttt atacctatca ttattttagt 1083901 gttaactgct tttctcgctt taataggata tatttcaatt atttttctcg gccattatgt 1083961 catagatgaa aaaaagctta ttcttcatgc ttcttcaaaa attgttgatc aaaacggaga 1084021 tgaggttgca agcctgtata cagaaaatcg cgagccggtc tcgatcaatg agattcctaa 1084081 gcaggtcaga gaagcgttta tcgctgttga ggataaaagg ttctatgagc atcacggcat 1084141 tgatgcaaaa tccgtcggaa gggcagtgta ccgcgatata ttagcaggcg gaaaggtgga 1084201 aggcggaagc acgatcaccc agcagcttgc caaaaatatt tttctgacac atgacaaaac 1084261 atttctaaga aaaacaaaag aagtgatcat tgcgattaat cttgaacggg attacagcaa 1084321 ggacaagctg cttgaaatgt atttaaacca gctttacttc ggacacgggg tttacggcat 1084381 acaagcggcg tcccactatt attttaataa agaagtaaaa gatttgactg tatctgaagg 1084441 cgctgttttg gccgctattc cgaaggcgcc ttctacgtac tctccaattt tgcaccctga 1084501 taaaaataag gagcggcgtg atacaattct aggtatgatg aatgaccaag gctatatcag 1084561 tgcgaaagag gctgtcaccg cacagggccg gacgcttgga ctgcatgtga agaaacagtc 1084621 ggaaacacct tggtttgaca gctacattga ccttgtgatc aaagaggcgg aagacaagta 1084681 ttccatttcc ggagagcagc ttcttcaagg cggatacacg atcaaggtgc cgctcgattc 1084741 gaagctgcag aagacggctt accaggtgat gaaagaggga agctattatc ccggaacaga 1084801 tcagaatgcc gagggaagcg cggtctttat taataacaag acaggcggtg tagaagcggc 1084861 catcggcgga agggattaca catccaaagg atataaccgt gtcacagctg tccgccagcc 1084921 gggttccaca tttaagccgc ttgctgtata cggaccggcg atgcaggaaa agaaatttaa 1084981 gccatattct ctattgaagg atgagttgca gtcctacgga gattatacgc cgaaaaacta 1085041 cgacagccgg tatgagggcg aagtcactat gtctgacgcc attacgtaca gcaaaaacgc 1085101 gccggctgtc tggacgctga atgagatcgg cgtcgaaaca gggaaatctt atttgaaagc 1085161 aaacggcatt gatatccctg atgaaggcct tgctcttgct ctaggcggct tggaaaaagg 1085221 cgtttcaccg ctccagcttg ccggcgcgtt tcatacattt gccgcgaatg gaacgtatac 1085281 tgaacccttc tttatctcga gcataataga tgaagacgga gaaacaatag ccgatcataa 1085341 agaagaagga aagcgggtat tcagcaagca gacgtcttgg aatatgacga gaatgctgca 1085401 gcaggtagtc aaaaagggaa cggccacgtc cggcacctat cacggcgacc tggcgggaaa 1085461 aacaggttca acatcttata caggcgtctc cggcgcgaca aaggacgcct ggtttgcagg 1085521 ctatacgccg aaaataaccg gggcagtctg gatgggctat gacaaaacgg atcaaaacca 1085581 ttatttgaaa gccgggagct catacccgac gcggctgttt aaggatattt tgacacaggc 1085641 aggagaaacc ggtcatgtgt tcacaaagcc taaaaacgtt aaagaactgg aaagcccgat 1085701 tgagctgaag ccggtcaaaa cactcacagc cgattacaca tttaaagcag cggggctctt 1085761 tactattgaa ttaaagtggg acgctcaaga ggatgatcgg gccgtataca gaatttatgt 1085821 aaacaaggac ggcgaggaga cgcttcttga ttcggttgaa gggaagggaa gctatgaaat 1085881 tccttatgcc aacttatttt cgggcgcgtc ttataaaatt gtgccttata atacacagac 1085941 aaaaagagaa ggggaaggaa ccgattacgt tcagccaaaa ttgttttcct cttaatggaa 1086001 ttcggcgatt ttttgaactt tgagctacat ttctatacca tttgcctaaa acaaggtata 1086061 gtgtaataag tcaagaaata cgaacgtatg gttgccgtat gaaaggtgga aatcagatga 1086121 gtaaacgaga aacgtttaac gagacgtttt taaaagctgc gcggggagaa aaagcggatc 1086181 acacgcctgt gtggtatatg aggcaagcag ggcgctcaca gccggaatac cgcaagctga 1086241 aggaaaagta cggattgttt gagatcacac atcagcccga actttgtgcg tatgtcacaa 1086301 gactgccggt tgagcaatac ggagtcgatg ctgcaatcct ttataaagat atcatgacgc 1086361 cgctgccgtc aatcggtgtg gatgttgaaa tcaaaaacgg gatcggtcct gtgattgatc 1086421 agccaatccg gtctctggcg gacattgaaa aactcggcca gattgatccg gaacaggacg 1086481 tgccgtacgt gcttgagacg attaaactgc ttgtcaatga gcagctgaac gtcccgctca 1086541 tcggtttctc aggtgcgcct tttacgcttg caagctatat gatcgaaggc ggcccgtcga 1086601 aaaactacaa taaaacaaaa gccttcatgt acagcatgcc agatgcatgg aatctgctga 1086661 tgtccaagct tgccgacatg atcatcgtgt acgtgaaagc gcagattgag gcaggcgcaa 1086721 aagcgattca aatctttgat tcgtgggtcg gcgcattgaa tcaggcagat tacagaacat 1086781 acatcaaacc cgtgatgaac cggatctttt cagagctcgc aaaggagaat gtgccgctga 1086841 tcatgtttgg cgttggcgca agccatcttg caggtgattg gcatgacctt cctctcgatg 1086901 ttgtcgggct tgactggaga ctcggcattg atgaagccag atcaaaagga attactaaaa 1086961 cagtgcaggg caacctggac ccgtccattt tgcttgcgcc atgggaagtc attgagcaga 1087021 aaacgaagga aatacttgat cagggtatgg agtcagacgg cttcattttc aatcttggcc 1087081 atggggtatt tcctgatgtc agtcccgagg ttttgaaaaa actgacagca tttgtccatg 1087141 aatattcaca aaacaaaaaa atgggtcaat attcctaagc atatcttttg gtatcttaat 1087201 gatatcctgt caaaatgttt gtatcagatc attaaagagg gtgtaaacag tgagtagaaa 1087261 gaaaatgggg cttctcgtga tggcgtacgg cacgccttat aaggaagaag atattgaacg 1087321 ttattataca catatcagaa gaggcagaaa gcctgaacct gaaatgcttc aagatttgaa 1087381 agacagatac gaagcgattg gcggcatttc accgcttgcc caaatcacag aacagcaggc 1087441 gcataatctg gaacagcact tgaatgaaat tcaggatgag attacgttta aagcgtatat 1087501 cggactgaag catatcgagc cgtttattga agacgccgta gcagagatgc ataaggatgg 1087561 cattacagaa gcagtcagca tcgtgctggc gccgcatttc tccacgttca gcgttcagtc 1087621 ctacaacaaa cgcgccaaag aagaggctga aaaactcggc ggcttaacga ttacgtcagt 1087681 tgaaagctgg tacgatgaac cgaagttcgt gacatattgg gttgaccgag tgaaggaaac 1087741 atatgcgtca atgcctgagg atgaaagaga aaacgcaatg ctcatcgtat ccgcacacag 1087801 cctgccggaa aaaatcaaag aatttggaga cccgtacccg gaccagcttc atgaatcggc 1087861 gaaattaatt gctgaaggcg caggcgtttc cgaatatgct gtcggctggc aaagtgaagg 1087921 gaacacgcct gatccttggc tcggacccga tgttcaggat ttaacacgtg atttattcga 1087981 acaaaaaggc tatcaagcat ttgtatatgt tcctgttggg tttgtcgcgg atcacttaga 1088041 agtgctttat gataatgatt atgaatgcaa agtggttact gacgatatcg gcgcaagcta 1088101 ttaccggccg gaaatgccaa atgccaagcc tgaatttatt gatgctttgg caacagtcgt 1088161 attaaaaaaa ttaggacgtt aaagaaggcg atgaacatga gtgacggcaa aaaacatgta 1088221 gtcatcatcg gcggcggcat taccggttta gccgccgcct tctatatgga aaaagaaatc 1088281 aaagaaaaga atctgccgct tgagctgaca cttgttgagg caagtccgag agtcggcggg 1088341 aaaatccaga ctgtcaagaa agacggctat atcatcgaaa gagggccaga ctcatttctg 1088401 gaacgaaaga aaagcgcccc gcagcttgtt aaagacttag gtcttgagca tttgcttgtc 1088461 aacaatgcga ccgggcaatc ctatgtgctt gtaaaccgca ccctgcatcc aatgccgaag 1088521 ggcgctgtaa tggggatacc gacaaaaatt gcgccgtttg tttctacggg tctgttttcc 1088581 ttgtccggga aggcgagagc tgctatggat ttcatcctgc ctgcaagcaa aacaaaggat 1088641 gatcagtcat tgggagaatt cttccgcaga cgtgtcggag atgaagtggt cgagaactta 1088701 atcgagccgc tactatcagg gatctacgca ggcgacattg acaagctcag cctgatgtcg 1088761 acatttccgc aattttatca gacggaacaa aagcatagaa gcctgattct cggcatgaaa 1088821 aaaacaaggc ctcaaggctc aggccagcag ctgacggcaa aaaaacaagg gcagttccaa 1088881 actctgtcaa ccggtttgca gacccttgta gaagagatcg aaaagcagtt aaagctgacg 1088941 aaggtgtata aaggcacaaa agtgaccaaa cttagccata gcggctcttg ctattcgctc 1089001 gaactggata acggcgtcac acttgatgct gattcagtaa ttgtgactgc tccgcataaa 1089061 gcggctgcgg gaatgctttc tgagcttcct gccatttctc atttgaaaaa tatgcactcc 1089121 acatccgtgg caaacgtcgc tttaggtttc cctgaaggct ccgtccaaat ggagcatgag 1089181 ggcacgggtt ttgtcatttc aagaaacagt gactttgcga tcacagcctg tacgtggacg 1089241 aataaaaaat ggccgcacgc agcgccggaa ggcaaaacgc tgcttcgggc atatgtcgga 1089301 aaagccggag acgaatccat tgtcgatcta tcagataatg acattatcaa cattgtgtta 1089361 gaagacttaa agaaagtcat gaacataaac ggcgagccgg aaatgacatg tgtaacccga 1089421 tggcatgaaa gcatgccgca gtaccatgtc ggccataagc agcgtatcaa ggagctgcgt 1089481 gaagcacttg catctgcgta tccgggtgtt tatatgacag gcgcttcttt cgaaggtgtc 1089541 ggcattcccg actgcattga tcaaggaaaa gctgccgtgt ctgacgcgct tacctattta 1089601 ttcagctaaa acctccgctt tatcgcggag gtttttttga tgtgcaatgg caatattgtg 1089661 taaaaaatga ttgaattgaa cagcaggtta tgatacattt gcatatgtac ttaatgacta 1089721 aaatgttcaa acggtcagtt tcgaggtgaa tacaatgtca atagatcgaa aaaagctcat 1089781 tttggaggcg gctacaaagt ctttcacgca gttcgggtat aaagcgacga caatggatct 1089841 tgtcgcaaaa cttgcgaacg tggggaaggg aaccatttat acttttttca aaaacaaaga 1089901 agagctgttt gacgagattt tcactacttt attaaaggaa atgaagcaaa aagcggatga 1089961 agcgatggag ccgagccttc cgttccatga aaatgtgcac agagcgctgt ttgccattct 1090021 ggagttcagg aaaacacatc agctgacgat taaaattttc caagagaatg ccgagattgg 1090081 tacaatggca gttcaggaag tgatccagaa aatggagcga tccatcctgt cttatatcaa 1090141 aagcaagatt gaagacggga tcaaaagcgg cgcaatcaag ccgtgcgacc ctgagctgac 1090201 agcctttgtg atgctgaagc tttatatcgc gctcattttt gactgggaaa aacaacaccc 1090261 cccgcttgat aaagagacaa ttgcgggact gcttgaattg tatgttgtca aaggattgtc 1090321 agcgaactag ataatccttt ctctttgcaa gaaaatgacc attttttatg atgagtcagt 1090381 tttagaatgg aggcatcagg atgaacacaa tacgaagtca gtggaaagac atcgtaacaa 1090441 gtaaaaaatt attgattccc atcatcgcca ttttgtttgt cccgcttatt tacagcggcg 1090501 tattcttaaa ggcttattgg gacccgtacg gcacagttga ccagctgcct gtcgttgtcg 1090561 tcaaccaaga caagggagca acgtatgaag gagaaaaact tcaaatcggt gatgatctgg 1090621 tcaaagaatt aaaggataat aacaactttg attggcattt ttccaatgat ctcgaccaat 1090681 cgttaaagga cttattgaat caaaaatatt atttagttgt cgagattcct gaggattttt 1090741 ctaagaatgc cagcactgta ttagacaaaa atccgaaaaa attggatctg aaataccata 1090801 caaatgcagg ttctaactat gtaggggcaa cgatcggcga aaaagcgatt gataaactga 1090861 aagcctctgt ttcaaaagaa gtgaccgagc aatatacgaa agttattttt gataacttta 1090921 aagatatcgc aaaaggtttg agcgacgcga gcagcggcgc gaaaaaaatt gatgacggca 1090981 caaaggatgc gaaaaacgga agcgcccagc tgaaagaaaa tctggcgaag ctgaaggaaa 1091041 gcaccgctac catcagtgac aaaacagcgc agcttgcaga tggagcggct caggtgacga 1091101 gcggcatcca atcacttgac agctcgctcg gtaaattcca ggacagcagc aaccagattt 1091161 atgataaatc tagtcagctt gcagcaggat caggcgagct gacaagcaag atgaatgaac 1091221 ttcttgccgg acttcaaaat gtgcagaagg gtacgcctaa tcttactaac gggttggatc 1091281 agctcaacag taaagtccaa gaaggttctg agaaagcggc aaaagcggaa aagatcatta 1091341 atgcgctcga tttaacgaag cttgaaactg ctgtaaacaa tctggaaaag tcagaaactg 1091401 cgatgaagga attcaaaaaa cagctgactg actttgaaaa cagtttgaaa aaccgtgatc 1091461 aggcatttaa aaatgtcatc aattcgagtg acttcttaac agcggagcaa aaaagccagc 1091521 tgattaattc tgttgagaaa aagcttccgc aagttgatgc gcctgatttt gatcaaatat 1091581 taagccagct acctacagct gatcagctgc ctgacatcgc aacgataaaa agctctcttg 1091641 aagacgtgaa agcgcaggtg gcgcaggtga aagccatgcc ggaagctaca tctaagcttt 1091701 ataacggcgc aaaaacaatc caagatgcga ttgacagatt aactgaggga gctgataaga 1091761 tatacaacgg ttctcagaag ctgacagatg gccaaactaa actgacagcg ggcatcggtg 1091821 aatataataa gcagttcgca aaagcaaaag cgggctcaga gcaattggtg acaggaagca 1091881 gccaagtatc cggcggattg tttaagctgt tagacgggtc taaacaggtc caaagcggat 1091941 catcaaaact tgcagacgga tctgcatcac ttgatacagg tttaggcaag ctattggacg 1092001 gcacaggaga gctgtctagt aagctgaagg atgcggctga ccaaacagga gatatcgatg 1092061 ctgatgatca aacatacggc atgtttgcgg atccggttaa aaccaaagat gatgccattc 1092121 attccgttcc taactatgga acagggctga caccttatat cctgtcaatg ggcttgtatg 1092181 tcggcggcat catgctgacg gttgtcttcc cgctgaagga agcgtcagga cgtccgagaa 1092241 acggttttga gtggttcttc agcaaattca atgtcatgat gcttgtagga atcattcaat 1092301 cattgattgt ggcgacggtt cttctattgg gaattggtct tgaggtagag agcacgtgga 1092361 gattttacgt gtttacgatc attacgagtc tcgctttcct ggcgataatt caatttttgg 1092421 ctacaacgat gggcaacccg gggcgattta tcgcagtcat tattttagtg ctgcagctgg 1092481 gagcgagcgg aggaaccttc ccgctggaat tgcttccgaa tttctatcag gtcatccacg 1092541 gcgcattgcc gatgacctac agcattaacg gattcagagc agtcatttca aacggtgact 1092601 ttggctacat gtggcagatg gccggcgtct taatcggcat tgccctcgtc atgattgcac 1092661 taagcattac ttactttaca atgttaagcc ggaaggaaga aacatcagaa gaacagccgg 1092721 cttcataaag aaaaagaact tgtttccttg gaaacaagtt ctttttttgt tacatccccc 1092781 atttaataag caatcctgta taggttaatc cgccgccaaa cccgaaaagc aaaacgattt 1092841 gatctttttt cagcttcccg gctttcactg cgagatcgag cgccaaaaca attgaaaccg 1092901 aagacgtgtt tccgtagtgc tcaacactag tgagcgtttt ttcaatcggg aacggtgttt 1092961 tttcacaaat tgactcgatc atgcgcaagt tggcgctgtg aggaacaaac caatcgagat 1093021 catcggagct gagtcctgct ttatgtaaaa gccgttcaaa ttcgccaggg acggttcttg 1093081 cggcccattt atatacctcg cgtccgtttt gcaccatttt tccggaaccg acaagctgca 1093141 caccgtttat ttcatttcgc agtccggcac gatacaaaat atcgccgccg ttcccgcttg 1093201 ttccttgtac agacgcaaga aatcccggcg tctcttcatc tcgttctact aacagcgcac 1093261 ccgcggcatc gccgaacagt acgcatgtcg ttcgatcggt ataatcggtt acctttgata 1093321 acgtctctcc ggcgatgacg agaatttttt gatgaaggcc agatgtgatc aatccatttg 1093381 ccaaatggag gccgtatgtc agcccggcgc atgtcgcatt aatatccagc gcgccggtgc 1093441 tttcccagcc gaaatattcc tgtacgcggc atgccgtact cggaaaggcg taatcggatg 1093501 tggttgtggc aacgaggatc atatcgacat catcaagcgt tcctttataa cggctcttga 1093561 gattcttcac cgcttctatg cataaatcag aggtaaattg atgttcatcc gcaatccggc 1093621 gttctctcat tcctgtgcgc tgaacgatcc attcatcaga ggtatcaacg atcttttcta 1093681 aatctgcatt ggttaaacgt ctgctcggcg cataggtgcc gatagctgta atttttgctt 1093741 ttgacatatg aatcactcct tatggtcaga ttataacact agatattagt atctggtact 1093801 aaaaagaagg tttttttaca aaaaaagaga agtgtagata ggaatctatg aaaaagaaaa 1093861 aggaggctga aaaatggtca gtcaagaagc agtagtcttt ttggcattat ccggggctat 1093921 tgcgtttctg ttgccaatcg ggctgattgt atggtttaag cgaaagtatg gtgcctcgct 1093981 taaagtgttt tttattggcg ctctcacgtt ttttgtcttc gctcagctgc tggaaggcgg 1094041 cgttcatgtt tatgtactgc aagtgaatga aatgacgaaa gaagcgatgc agcatccatt 1094101 atggtatggc atttacggct gcttgatggc cggcattttt gaggagtgcg gaaggtattt 1094161 gatgatgcga ttttttatga agcgccatca tacttgggca gatggtctgg ctttcggggc 1094221 aggccatggc gggcttgaag ccatcctgat tacaggcttg tcctctatct cacttattgt 1094281 atacgcattt gcaatcaata gcgggacgtt tgaacagctt ttggtcaatg gcgacgtcaa 1094341 acaggcgctt ttgccgatac aggagcagct gctgcatact ccttcgtatg aatggatgct 1094401 gggcggaata gaaagaatca gtgccattgc cgtccagatt ggtctgtctc tgcttgtttt 1094461 gtacgcggtt aaaaaccgcc ggccgctgtt tttgctgtat tctattcttt tacatgcact 1094521 gtttaatgtc ccggcggttt tatatcaaag aggaatcata gagcatgctg cagctgttga 1094581 aatcattgtt gctcttatag cggctttatc agtttattgg attgtaaaag caaaaagggt 1094641 gtttcaataa aaggtccaag cagcagcaat gcccgcttgg aaaaatgtga atggaaatat 1094701 tcattaagca tgggtcatca gaatatttct gattcagtct ttagcaatga cagcaagaat 1094761 gtctgtgttt tttacaagag aaacaatggt gtttcttttt cttcttctcg caagggtcat 1094821 ggcattcttt ctttttcttg caatggtcgt ggaaatcttt atcgaaccac tcgtcaaaga 1094881 accaaaaatc atcgaaccaa tcgtgacaac gacatttctg ttcatgtgaa tgacgacagc 1094941 acatagaaat ccctcctctt cccatgctct ctacagcata tgagagattg ataggaaaag 1095001 attggacggg tccctcggga aaagagtata ttttaagtag aaaataaaag gaggaatgcc 1095061 ctatgacgtc cgtacgtaaa acgatggagc tcattaaaga acttgtatcg atcccaagcc 1095121 cgacaggaaa tacatatgag gtgatcaatt atattgaaag ccttttaaaa gaatggaagg 1095181 tagaaacggt tcggaaccac aagggcggct taattgcaac gcttccagga cgcgacacat 1095241 cccggcatcg catgctgaca gcgcacgttg acaccctcgg cgctatggtg aaggaaatta 1095301 aagcggacgg ccggctgaaa atcgacttaa tcggcgggtt ccgctacaac tcgattgagg 1095361 gggagtattg ccaaattgaa accgcctcgg gaaaaatgta cacaggcaca atcttaatgc 1095421 atcaaacgtc tgtgcacgta tacaaagacg cgggaaaggc tgagcggaat caagagaata 1095481 tggagatccg cctagatgaa cctgttcact gccggaaaga tacggaggag cttggcattg 1095541 gcgtcggaga ctttgtgtcg tttgatccac gtgtcgagat cacatcaagc ggatttatta 1095601 aatcgcgcca tttggatgac aaagcaagcg tcgccttatt gctccgctta attcatgaaa 1095661 ttcaaacaga agacattgag ctgccgtata caacccattt tcttatttcc aataatgaag 1095721 aaatcggtta cggcgggaat tcgaatattc ctcctgaaac agttgaatat ttggcggttg 1095781 atatgggcgc tatcggtgac gggcaggcga cggatgaata ttcagtatca atctgtgtga 1095841 aggatgcgag cgggccgtat cattatcagc tcagaaagca tttagttcaa ttagccgaga 1095901 agcatcatat tgactataag cttgatatat atccgtacta cgggtctgat gcgtcagcag 1095961 cgatcaaatc cgggcatgat attgtgcatg gcctcatagg gccgggaatt gacgcttccc 1096021 atgcatttga acgcacccat aaatcatctc ttcgccatac cgctaagctt ctgtattact 1096081 atgtacagtc accaatggta taagggggag gaccaatgaa gatttataag ctgaaaagca 1096141 cattcggttg ggaaggtgat gacgggttgg gagaacagct gattcagcag atccttgccg 1096201 gagaaaaaag cgccacgtgc gcgccgaaat cattgtattc aaaagatgaa ttgagggacg 1096261 tttatcaaac agcgggtcag cttgttaccg tttatgataa acatgacaat ccaagatgca 1096321 atataaaagt aacagatgtc tttgaaacca cctttggtgc gcctgatatg aggttagtca 1096381 aaggagaggg caatggagac cgaattgagg agtttcaaga ggatcatcgg atggcatggg 1096441 cggaactgat caaaagcggt gaactggagc tgaatgagga tactgttttg attacagagt 1096501 tgtttgtgct tgttaaagat taaaaaagcc tgcggggcaa gaaccccgca ggcttttcat 1096561 taaccagaaa tggttgcgtt ttgttctgtt ttcgattggg acataacagt ttctgctttc 1096621 gcaggattaa acatgccttc ccatttagac atcacaacgg cagcaagcgc gttaccagtc 1096681 aggttgacaa ctgtacgtgc catatccatg atgcggtcta cgccggcaat aaaggcaagt 1096741 ccttcagccg gaacgccgat ggtgccaagc gttgcaagca agacaacaaa agaagtacca 1096801 ggtacggcag ccatcccttt ggatgtcacc attaagacga gcacaagcgt aatttggtgc 1096861 caaatcgtca aatcaatgcc atatacctgt gctaaaaaga gtgcggcaat agattgatag 1096921 agaacggaac cgtctaagtt aaacgtgtaa ccgatcggaa tgacaaatga aacaatgcct 1096981 tttggacatc cgattttctc cattttttcc atgatacgcg gaagaaccgt ttcagagctg 1097041 gacgtactga acgccagtaa gatttcgtcc ttcatgtaag caaggaactt gaagatgctg 1097101 atgccggcaa tttttgcgac aatcccgaaa ataacaatta agaagaaagc aagcgcgaca 1097161 taaaccaatc cgacgagctt tccgagagag ataagagaac cgagtccgaa tttagacaca 1097221 gtcactccga taagagcgaa aacgccgaat ggcgccactt tcatcacaag gtttacaacg 1097281 tggaacatgg catgggatac accttcaaaa aaggctaata caggcttgcc tctttcaccg 1097341 atcgcggaaa tacccaatgc aaatagtact gtaaagcaga tgatggctag aagatcccct 1097401 tcgaccaatg actggaagaa gtttgtcggc acaatatgga ggaacgtttc cgccactgat 1097461 ttattacttt gttctttttc agtttcaaca tattgactga tgtccgattt ttgagcttcg 1097521 tgtatattaa ctcctgtacc cggatggaag atgtttgcaa gggctagtcc gagaataatg 1097581 gcaaaagtcg tgatgatctc gaagtacaga atcgttctga agcctaattt accgacttgc 1097641 tttccatttc ctgcaccggc tacaccgatg attaagctgg agacaacaat aggaatcact 1097701 atcattttga ttaagcgtaa aaagagatcc ccgattggct gcaggtaagt aggcaatgct 1097761 gggttgccat accaaatgac gccaacaatg acacctagaa taagtccaac gaatatttgt 1097821 gtggctaatc caaacttaat tcttttcata gattacctcc caaaaaacaa agtatcaaca 1097881 tatatcatga atagacatat atttaatctc actattagat caaattataa tagataagaa 1097941 atcaattcgt ctatagtaaa ttatatttcg aaaataaaga atattcaatg acattatgat 1098001 aatcaccaga attatctaaa aacaggtgag ctttgaccta acctgactat tatttcaaaa 1098061 ttaagagata tgtgaaaaaa taagaaaatc ccacgcgtaa ggcgcgggat tttcgctcat 1098121 tacaaatcgt ttacttttat acagtcattg cagatattac cataacactc atgctgctct 1098181 tctatctttt ttccgcattc cgcacacttt ttcgaaggca ggtttctaaa aaattctgtg 1098241 attttcccca gcataaccaa tccctctttc ccctttgtag tgatttcatt gtaatataac 1098301 agattacaaa aatcaataac tgttttgata caatgtttaa aacatgcttt tttcaagaaa 1098361 aatgggtata ttgaaggagg accaattttt ttgaaaagat aggaggacat tatgaaagtt 1098421 acagttatcg gatgctatgg cggttttccg gccgcaaatg aagcgacgtc aggctatttg 1098481 tttcagtcag gtgattactc tctgcttgtt gattgcggca gtgccgtatt gtctaagctg 1098541 ttcggatatg tgccggcgga aaagctggat gcggtcgttc tgtctcatta tcaccatgac 1098601 catatcgctg atatcggacc gctgcaattt gccaagcaag tcggttcgtt tctcggcaaa 1098661 ggagagcata cgcttccgat ttacggacat gatgctgata tagaacagtt tcaaaagctt 1098721 acatataaaa cacatacaaa agggatcgcc tatcagccgg atcagccgct gactgccggt 1098781 ccgtttacga tcaccttttt aaaaacgatt cacccggtga cgtgctatgc catgcggatt 1098841 actgacggca gccacactgt cgtttatact gctgattcca gctatcagga ttcatttata 1098901 ccgttttcga aagatgctga tttattgatc tcagaatgca atttttatgc cgatcaagac 1098961 ggaacaagtg caggccatat gaacagcctg gaagctgggc gcattgcaaa agaagccgga 1099021 gcgggagaac tgctgctgac acatttgccg cattttggcg tgcatgacaa ccttcgcaaa 1099081 gaagcgaaaa ccgtttttaa cggagaagtg aatattgcga aatcaggttt tgtgtgggaa 1099141 ggataaagga ggagcaccat gttatttata gacaatcaaa atatcaatga tccgcggatc 1099201 aatcttgcta tcgaggagta ctgtgtaaag catttagacc ctgaacagca atatttgctc 1099261 ttttatgtga atcaaccgtc tattatcatt gggaaaaacc aaaatacaat agaagaaatc 1099321 aatacaaaat atgttgagga aaacgggatt atcgtcgtcc gccgtttatc aggcgggggc 1099381 gctgtgtacc atgatctggg gaacttgaac ttcagcttta ttaccaagga tgacggggac 1099441 agctttcata actttaaaaa attcactgag ccagtgattc aggcgttaca tcagcttggg 1099501 gttgaagccg aattaagcgg ccggaacgac attgtagtag atggccggaa aatatccgga 1099561 aacgctcagt ttgcaacgaa aggccgtatt ttcagccacg gcaccctcat gtttgattca 1099621 gccattgatc atgttgtatc agcattaaag gtgaaaaagg ataaaattga atcaaaaggc 1099681 atcaaatcga tcagaagccg agtggcaaac atcagtgagt ttctcgatga taaaatgacc 1099741 accgaagaat tccgcagcca tttgcttcgc catattttta acacaaacga cgttggaaac 1099801 gtgccggagt ataagctgac ggaaaaagat tgggagacca ttcatcaaat ttcgaaagag 1099861 cgctatcaga attgggattg gaactacggc cgctcaccaa aatttaacct taatcattcg 1099921 aagcgttatc cggttggatc gatcgatttg cacctggaag tcaagaaagg caaaatcgag 1099981 gactgcaaaa tcttcggaga tttcttcggt gtcggtgatg tatctgaaat tgaaaacctg 1100041 ctggtcggaa aacaatacga acgcagcgtc atcgctgatg tgctcgaagg tgtgaatctc 1100101 aagcattact ttgggaacat tacgaaagag gatttccttg atctgattta ctaaggcaaa 1100161 acacatcgtt tgaaagagcg gttgtgtttt tgaaataatg gaggcaggag ggattcacat 1100221 gaaagtgttt ttaatcggag cgaacggaca aatcgggcaa agactcgtct ctttattcca 1100281 agataatcct gatcattcca tcagagcgat ggtcagaaaa gaagaacaga aagcgtctct 1100341 tgaagctgcc ggtgcagaag ctgtgcttgc gaatctggag ggcagcccgg aagaaatcgc 1100401 cgctgcggca aaaggttgtg acgcgatcat tttcacagcc ggttccggcg gcagcacagg 1100461 ctatgataaa acgctgctgg tggatcttga tggagcggca aaagccattg aagctgcggc 1100521 cattgccgga atcaaacggt ttattatggt cagcgccctg caagcccata accgtgaaaa 1100581 ttggaatgag gcactcaagc cttattatgt ggccaagcat tatgctgata aaattctgga 1100641 agcgagcggt ttaacctata cgattatccg tccgggaggc cttcgcaatg agcctggaac 1100701 gggaactgtt tcagcagcga aggatctgga gcggggattt atttcccgtg atgacgttgc 1100761 aaaaacggtc attgcctctt tagatgagaa gaatacggaa aatcgggcct ttgatctgac 1100821 agaaggagat acgccgattg ccgaagcatt gaagaaacta tgacagtact gacactcagg 1100881 gctttttgct cttgagtgtt tttttctgtt tctctataat ggagaagaaa gcttggcttc 1100941 aataatgaat gactattcat tcacttaagg ggtgggagaa tgaatcttgt ttcaaaattg 1101001 gaagaaacag catctgagaa gcccgacagc atcgcatgca ggtttaaaga tcacatgatg 1101061 acgtatcaag agctgaatga atatattcag cgatttgcgg acggccttca ggaagccggt 1101121 atggagaaag gggaccattt agctttgctg cttggcaatt cgcctgattt tatcatcgcg 1101181 ttttttggcg ctttaaaagc tgggatcgta gttgttccca tcaatccgtt gtacacgccg 1101241 acagaaattg gttatatgct gacaaatggc gatgtaaagg caatcgtggg cgttagccag 1101301 cttttgccgc tttatgagag catgcatgaa tcgctgccaa aggttgagct cgtcatttta 1101361 tgccagacgg gggaggccga gccggaagct gcggacccag aggtcaggat gaaaatgaca 1101421 acgtttgcaa aaatattgcg gccgacatct gccgctaaac aaaaccaaga acctgtacct 1101481 gatgataccg cggttatttt atatacgtca ggaacgactg gaaaaccgaa aggcgcgatg 1101541 ctgacacatc agaatttgta cagcaatgcc aacgatgtcg caggctattt gggaatggat 1101601 gagagggaca atgtggtctg cgctcttccc atgtttcacg tgttttgttt aaccgtctgt 1101661 atgaatgcac cgctgatgag cggcgcaact gtattgattg agcctcaatt cagtccggca 1101721 tctgttttta agcttgttaa gcagcagcag gcgaccattt ttgccggtgt gcctacaatg 1101781 tataactact tgtttcagca tgaaaacgga aagaaagatg atttttcttc gatccggctg 1101841 tgcatttcgg gaggcgcgtc catgccagtc gcgttgctga cggcgtttga agaaaaattc 1101901 ggtgttacca ttttggaagg ctacgggctc tcggaagcat cacccgtcac gtgctttaac 1101961 ccgtttgaca ggggcagaaa gccgggctcc atcgggacaa gtatcttaca tgtcgaaaac 1102021 aaggtcgtag atccgctcgg acgcgagctg cccgctcacc aggtcggcga attgatcgtg 1102081 aaaggcccca atgtgatgaa gggctattat aaaatgccga tggaaacaga gcatgcatta 1102141 aaagacgggt ggctttatac gggggacttg gcaagacggg atgaggacgg ctatttttac 1102201 attgttgacc ggaaaaaaga catgatcatt gtaggaggat acaatgtgta tccgcgggag 1102261 gtggaggagg tgctgtacag ccatccggac gtcaaggagg cggttgtcat cggcgtgccg 1102321 gacccccaaa gcggggaagc ggtaaaggga tatgtggtgc cgaaacgctc tggggtaaca 1102381 gaggaggaca tcatgcagca ctgcgaaaag catctggcaa aatacaagcg gcctgccgcc 1102441 attacgtttc ttgacgatat tccgaaaaat gcgacgggga aaatgctcag acgggcactg 1102501 agagatattt tgccccaata aaatgaaaaa gcgaagcggt tagcttcgct ttttcatttt 1102561 caatcctttg cttctttttt aataatattt agcagcgcct ttgtatcatt tttgcttaat 1102621 ttgtagtatg tgccatcctt caaaaaaacg gcttgctggc tgccgtcaat ccatagtctg 1102681 aatgagtcat accggtcttt atgaaacttg attgtccctt cgtaatcagg ggctgatgtt 1102741 ttttctgtct tcacctgttt tccctgattc ataatatcca gcatatcttt gacgtgctgt 1102801 cttttttcaa tctcgatatc ttcctggccg cttgaagaca gtgtgatcaa atccgcgtct 1102861 accgattgat acacatcgcc tgatcggctg taaagataaa aaaatgcgat aaacacaaga 1102921 ccgattacca cgatggctgc cactattttt ttcatttgca tcactccaaa cattgttagt 1102981 tttcccagcg atcggggttt ccatgcttaa aagggtggaa aagtgcggaa cacagcttgg 1103041 ttctaagaat ttgaatttat gattacaata gaagtaacgg gttgatgtga ggagtgaggc 1103101 gttatgcgca agtggattgc ggcagcagga cttgcttacg tgctgtacgg gctgtttttt 1103161 tattggtatt ttttcctgtc gggtgattcc gcaataccgg aagccgtgaa agggacgcag 1103221 gctgatccgg cttctttcat gaagccgtct gagttggcag tggccgagca gtattcgaat 1103281 gtcaagaatt ttttattttt tatcggggta ccacttgatt ggtttctgtt ttttgttctg 1103341 cttgtcagcg gtgtttcaaa gaaaatcaag aaatggatcg aagcggccgt gccttttcgg 1103401 tttttgcaga ccgttggttt tgtgtttgtg ctttcgctga ttacaacatt ggtgacgctg 1103461 cctttagatt ggataggcta tcaagtatcg cttgactata acatttccac acagacaacg 1103521 gccagctggg ctaaggatca ggttatcagc ttttggatca gctttccaat ctttacgctt 1103581 tgcgttctcg ttttttattg gctgatcaaa aggcatgaaa aaaaatggtg gttatacgcc 1103641 tggctgttaa cagtgccgtt ttcgctgttt ctgtttttta ttcagccggt cattatcgat 1103701 cctttataca atgattttta tccgctgaaa aacaaagagc ttgaaagcaa aattttagag 1103761 ctggcagatg aagccaatat tccggctgac catgtatatg aagtgaacat gtcagaaaaa 1103821 acaaatgcgc tgaatgccta tgttacagga attggggcca ataaacggat tgtattgtgg 1103881 gatacgacgc tgaacaaact tgacgattca gaaattctgt ttattatggg ccacgaaatg 1103941 ggccattatg tcatgaagca cgtttacatc ggtctggctg gctatttgct cgtgtcgctc 1104001 gccggatttt atgtcattga taagctttac aagcggacgg ttcgcctaac ccgcagcatg 1104061 tttcatttag aagggcggca tgatcttgcg gcacttccgc tgttattgct tttgttttct 1104121 gttttgagct ttgcggttac gcctttttct aatgctgtct cgcgttatca ggagaataag 1104181 gctgaccagt atgggatcga gttgacagag aacagagaag ccgctgttaa aacgtttcag 1104241 gatttggccg tgacggggct gagccaggtt gatcctccgg tgcttgtgaa gattttcaga 1104301 ggcagccatc cgtcgatcat ggaacggatt caacatgcgg agaaagaaga gaatgcgccg 1104361 gaacatcagg atgctgacaa ataaaaagaa gcaggtatgg aggaacctgc ttctttttac 1104421 tattattgtg cagctgcttg tacgttgatt aacccttttc catagtagaa agagtttcca 1104481 agatatgttg cagtgctttc taaacgatca cggacttgcg cgtttgtcca agtcgggtgc 1104541 ttagaaagaa ttaacgctgc tgctccggca acgtgaggag tcgccatgga cgttccgtta 1104601 taagcgccgt aagtgcctcc aggaagtgtg ctttggatgg acacgccagg agccatcaca 1104661 tcaagctcag aacctgcgct ggagaatgaa gctctttggt tgctgctgtt taccgcacct 1104721 actgcaatag tagaaggata ttttgcaggg tagccgactg tgcttgtgct tccggatgaa 1104781 ccttcgtttc cggctgcggc agcaacgacg ataccgctgg aaacggcttt gtcaacgact 1104841 gttttcagcg ctgtagaacc agtaggtccg ccaaggctca tgttgataac atccatattg 1104901 ttggaaatgg cccactcaat gccgttaata atccagctat attggccgct tcctgttgaa 1104961 tcaagcactt ttactgcata taatgatgcg cttggcgcta cgcccagaac accgattgag 1105021 ttattaagag cggcaatcgt accggctaca tgcgtaccgt gagaactgcc gtcctggtat 1105081 gggtttgttt cagaaggtac gaagcttgct ccgcctctga cgtttaagtc aggatgagaa 1105141 gagtcaattc cgctgtcgat aacagctact tttacgttag agcctgtgta gccttgagag 1105201 tgaagagccg gcgctttaat ttgagaaatg ccataaggaa cagattgcgc atattcatgt 1105261 gcaatatgat cttcttccac atatgcaacg ctcggatctt ttttcaattc ttttacagct 1105321 ttttcatcca atgttgctgc ggccgcgtta acatacttaa attgcttttg aacctttccg 1105381 cctttttcag aaataacatc ctttttcttg gcggaactca tggcactcat tgtctgttta 1105441 aatccgacaa tgtatttctt ttctgtactg ctttttccgg cagcctgcgc agacatgttg 1105501 ctgaacgcca tcgtaaagat taacgttaac gcaaacaaca agctgatcca caattttttg 1105561 cttctcactc tttaccctct ccttttaaaa aaattcagag tagacttact taaaagacta 1105621 ttctgtgaat ttattgtaat agatggaata atattttagt agacccattt ttttgagatg 1105681 attttatctc tatttaggta tatcatctct cgctatttcc gtagagactc gaaataacta 1105741 ttttcataca gaaaagaacg aaaatagaca tgagtaaatg ttcattatgc tgaaatgtca 1105801 tgctttttta ggttaaatgc tcctgagtcc cggcaaattc ctgtcgaaaa aattcgttca 1105861 aatgacctgc gtgtgcttcc gtgagaacaa tggatattat cgtgatattt tttcaaagca 1105921 tgatgataaa agtattctga aaaataaact ttacagaaaa gggatagaat gaaaaaatta 1105981 ttgagaggga ggaagaaata agatgaacat tcgccaagca aagacatcag atgcggccgc 1106041 cattgcgccg ctgtttaacc aatatcggga attttataga caggcatccg atttgcaagg 1106101 ggcagaggct tttttgaaag ctcgtttgga aaatcacgag tctgttattt tgatagcaga 1106161 agaaaatgga gaattcatag gctttaccca gctctatcca acgttttctt ctgtgtcaat 1106221 gaaaaggata tacatattaa atgacttatt tgtcgttcct catgcgcgta caaagggagc 1106281 cggcggccgg ctgctttctg ccgcaaagga ttatgcaggg caaaacgggg caaaatgttt 1106341 aacacttcag actgagcacc acaaccggaa ggcaagaagc ttgtatgagc aaaacggcta 1106401 tgaagaggat accggatttg tccattattg tctcaatgtg ccggcgaagt gaaaatggcg 1106461 gcttgatgat ttggtttttt gaacgttctt cggttacgat ataaatgaaa aggagtgtgc 1106521 cgaatgtcaa cgttatttca agccttgcag gcagaaaaaa atgccgatga tgtttcagtc 1106581 catgtgaaaa ccatatcaac agaggatttg ccgaaggatg gtgtcctgat taaagttgct 1106641 tattccggca ttaattacaa agatggtctg gccggaaaag caggaggcaa tatcgtcaga 1106701 gagtatccgc ttattttagg cattgatgct gcgggtacgg tcgtctcttc caatgatccg 1106761 cgttttgcgg agggggatga ggtgatcgcg acaagctatg agctcggtgt ctcacgtgat 1106821 ggcggattaa gtgaatacgc ttcggtgcct ggtgactggc tggtgccttt gccacagaat 1106881 ctttcgttaa aagaagcgat ggtgtacgga acggcgggat ttactgcggc gttatcagtg 1106941 catcggcttg aacagaacgg tctgtctccg gaaaaaggca gcgtgctagt cacaggagca 1107001 accggcggtg tcggcggaat tgcggtatcg atgctgaaca agcggggtta tgatgtggtg 1107061 gcaagtaccg gaaaccggga ggcggctgat tatttgaaac agcttggtgc aagcgaagta 1107121 atcagcaggg aagatgtcta tgacggaacg cttaaggcgc tgtccaagca gcaatggcag 1107181 ggagcggttg atccagtcgg cggaaaacag cttgcctcgc ttttaagcaa aattcaatac 1107241 ggcggatctg tcgcagtgag cggcttaacc ggcggaggag aagttccggc aaccgtgtat 1107301 ccttttattc ttcgcggagt aagcctgctc ggaatcgatt cagtatattg tccgatggac 1107361 gtcagagccg ctgtttggga gcgcatgtct tctgatctca agcctgatca gctgctgacc 1107421 atcgtggaca gggaagtatc attggaagaa acgccgggtg cgttaaaaga tattttgcaa 1107481 aatcgcattc aaggaagagt gattgtgaag ctttaacagg atcagcttgc agagaatgtt 1107541 atttttctgc aagctttttt gtggacagga tgatcagctg ctgaactgct gtgtcgcgaa 1107601 acaagatttt cctgtaagcc gaactttctc ttctcatttt aaaaataatt ggtgataatg 1107661 attctcattc cgtgttatac tactcttgga catcttaacc atagaaacta ccaacaggag 1107721 agactggaac atatgaaaaa aacactgatt attcttacag ttttacttct ttctgtctta 1107781 acggctgctt gctcgtcttc aagcggcaat caaaacagta aagaacataa agtggcggta 1107841 acacatgatt tagggaagac aaatgtgcct gagcatccga agcgggttgt tgttcttgag 1107901 ctaggtttta ttgatacact gcttgatctc ggcattacgc ctgtcggggt tgccgatgac 1107961 aacaaagcga agcagctgat caacaaggat gtgctgaaga aaattgacgg ctacacatct 1108021 gtcggcactc gctcacagcc aagcatggaa aaaatcgctt cattaaaacc cgatttaatt 1108081 attgctgaca cgacccggca taagaaggtg tacgatcagc tgaaaaaaat agcgccgacg 1108141 attgcactta ataatttaaa tgctgattat caggatacaa ttgacgcttc gcttacgatt 1108201 gcaaaagcag tcggcaagga gaaggaaatg gagaaaaagc tgacggcgca tgaagaaaag 1108261 cttagcgaga caaagcagaa aatcagcgcg aacagccagt ccgtgctttt gatcggaaat 1108321 acaaatgata ccattatggc cagggatgaa aacttcttta catcgagact tttaacacag 1108381 gtcggctacc gatatgcaat cagtacgtca ggcaatagcg attcaagcaa tggcggcgac 1108441 tctgtgaata tgaaaatgac actggagcag ctgctgaaaa cagatccgga tgtgatcatc 1108501 ctgatgacag gaaaaacaga tgacctcgac gccgacggta aacgcccgat cgaaaagaat 1108561 gtcctttgga aaaaactgaa ggcagtgaaa aacgggcatg tataccacgt ggatcgtgcg 1108621 gtgtggtctc tgcgccgcag tgtagacggg gcgaatgcca ttttggacga gcttcaaaaa 1108681 gagatgccgg ctgctaagaa ataaaagaaa agacaggcaa acgcctgtct ttttcttatt 1108741 tgataaagcc ggataagtgg ctgttgatat tatagtcttt tatccgccat ttttcttctg 1108801 caaattcaat gttgctgagg caggcgttga cgagacgggt gctttgaagc tccgggtcac 1108861 cgccggatat ttctgtcagc agggcgtgaa ttgccgcacc gtgcgccacg atcagcacct 1108921 tcttgtttgg atacgcctga ttcacttttg ccaaaccgcc catcagcctg tcagtgagtt 1108981 cttctaaggt ttccatattc ggatagatgt tatctggata gcgctttgtc cgttcctcca 1109041 gcggcatgcc ctccgcgtcg ccgtaatcgc gttccttaaa atcatccatc tcgactatcg 1109101 gaagatgcag atattcatta ataatttccg cggttctttt cgctcttttc agcgggctcg 1109161 tcacaataat atcccaagaa aagtccttta catattctcc ggtttctctt gcttggcgtt 1109221 cacctgttgc gtttagcggg atatcggttt tgccttggca tttttgctgc aggttccaat 1109281 cggtttctcc atgtcttact aaacaaacgg ctgtcataaa atccccttcc tgactttatt 1109341 catatcgcta ttatactaaa tcgaaagcgt gtgtcctatg aaaaagccta tgcaagaact 1109401 tcaaataata aagccagtcc gattccgccg ccgcttccga tggctgcaac agcatattga 1109461 cagtctggcc gtcttttcgc ttcataaaac aatctggtta ccagagctgc acctgatgca 1109521 ccgtacggat ggccaagagc taaggcgccg ccgcgcacat tgatttttga aaagggaatg 1109581 ccgagttctt gcgagcagac acaaattttg acggcaaagg cttcattgat ttcaaataaa 1109641 tcgatatcat caggtgttac atcgtgtgta tgtaagagct gacgaatcgc gacaaccggt 1109701 gccgcgggcg gaaagttggg gtgaatgccg ctgacagcgc tgccgataaa ccgaagcaca 1109761 ggcttaagtc ccagggctgc tgctttttct tcttccatta ccaaaagagc ggctgctccg 1109821 tctgctatgc cactgctgtt ggctgctgtg actgttccgg agctggtgtc gaaaaccggc 1109881 tttgcacggg gaataatcgc ttctattggc cgcgttttca aaaatgcttc gtccgtctcc 1109941 aattccccga gagcaacaac ttcttcacgg taaaatcctt catcatgcgc gttcctgctg 1110001 cgttgatggc tgagaagcgc gtactcatcc tgcatgcttc tgctgatgga atagcgtgca 1110061 gccgtatatt ctgccgcaat gcccatgtct ggatcgccga tcgcatctgg agaaaagcga 1110121 gcccgttctg aaaaagggga ttggctgctg ctttctgagc cgcccgcgat atacatcgtg 1110181 ccggctcccg cttgaataag gctgcaggca tagcgcacag cttcaaggcc ggagccgcac 1110241 tgtctgtcaa ttgtcattcc gggaaccgat aaaggcagtc cggcttgaag ggctgacagt 1110301 ctggccaggt tgccgcctct gccagtagcg tttccgagaa tgacctcgtc aacttgatcc 1110361 tctagctttc ggctgagaca gcggatgatg ggagccgcca aatcctccgg caggaagggc 1110421 ttcagcagtc cgttttgatt tccaaagatc gttcgttttg catcaacaat aaccgcattc 1110481 atttatactg tacactctct tccagccatt ttttcactct ggaacgggca atttttccgc 1110541 tgctcgtttc cggcaagctg tctgcaaaca cccatttttt cggaatttta taggaggcta 1110601 atttctgttt acaccaggct ttcagtgttc tggcattagc gtttccaaga atgacagcta 1110661 cagcgatttc tccccaatac tcgtcgggaa tgccaacgac agccgcgctt tcaacctctg 1110721 ggcaggcgag aagcacacgt tcaatttctt ctgggaaaat atttaatcct ccgtacacga 1110781 tcatcccgtt ttctcttcct gatatgtata gaaagccctc ttcatcaacg tagcccatat 1110841 catctactgt catccattca tctggtgtgc tgccgttcac atagccggaa aacctcatcg 1110901 ggcttttgac aaatattttt ccgatttctc ctggctggca gcgttctcct ccagcgttgc 1110961 ggatttcgat ccggacatta tgaaaagggc ggcccgctga atgcggcttc cgtttgctgt 1111021 cttccggtga agaaaacgtc acaaaactaa gctctgatgt gccgtaaaaa tcgtacagct 1111081 tgagatgagg ccatgcagcg gcaagcttct tcttggattc tgccggccag tctgcgccgg 1111141 atgaaatgat tttgacggga ctgtcgggaa aaccctcaat ccttgcgagg gcgtctgtca 1111201 tcgtcggtac ggtatagaga acactgatgg attcacggca cagccattcc ttcgctttgg 1111261 caggagaaaa ctttttcagc aaacaaacgg ttcctccgag aaacaaagtg ctgacagccc 1111321 catataggaa gtgagaggac attaacgctc cgggaatcag aaccttatca tctgatgaaa 1111381 tcgaaaaatc tgtttctgta caggtaaagc tctccatcca tgagcggtga gatcgcgtaa 1111441 aggccttcgg ttttcctgtc gagcccgacg taaatcccat ataaaaaggg tgctccggat 1111501 caatggtagg caagggatca gcggctgcct cagaaatatc tgccatacag ttatccagca 1111561 atacaacagg tgtctggcta tctgtcagtt tgtttttgaa aaaggctaaa gtaaccacaa 1111621 gatccgcatt gcttatggac agccgctcct tacattcagc cgggctccag cgtgtgtcga 1111681 tgggaatggc cgtacatcca gccgctgcgg ctccggcaaa cagctgtaaa aacgcgagac 1111741 tatttgggag caggatcgcc acacgattcg gcatgctcgg ctgtgaccgc agccaatttg 1111801 cggtttgaga gacaagccga tcccaatcat ggtacgtgat ttgctccgat tcagtctgga 1111861 tcgctacacg gccgggcgat gtttcggcag tagatgaata ggtatgagta attgtcatgt 1111921 attgtcatcc tccttttgta aacatcgtat cagaaagaga caaggcttga gtgattttta 1111981 tcgccagaaa tgcagataca gccgctttta tcaaatcacc aggcacatat gcaaggctca 1112041 tgaaggcggc ctgtgacaaa tcaatatgca tgataaaagc ttgtaccggt ataccaagca 1112101 gataaataaa gatgatgccg aatacgatat gagtgaaaaa gagacgcaat actgtcacct 1112161 tccgcagcct gttagcggct aaactgatca gccatgaagc gaggggataa gcaatcaaaa 1112221 agcctgcgct cggtccgaaa aacacaccaa aaccgcctcg tccgccgggc aacagcggcg 1112281 ctccgaaggc gacgagcagc aaaaagacaa gctggcttaa gaaagcagac tttggcctga 1112341 gaatgctgcc tgccaacatg acaccaagcg tttgcaatgt aatcggaacg ggtgtaaagg 1112401 ataagaagag agggggcata aagccgagca ctgccatcag cgcggtgaaa atcgcaatat 1112461 gcatcatgtc gattaatttc agcatgtgaa atcctccaaa aagtaatcaa atatggttat 1112521 acaataaatg caggtaatta ttatgtcaac tgatttttaa tttaagttta cataatgaac 1112581 gcaaaaaaac cggccgtatg gcagaccggt ttttgatggt tattcttctg tcaggatgac 1112641 aagcgaatca acggaagcgg ccacatggga aacggcgcgg ctgacttcct gaagccctcc 1112701 aagaaaggct tgcagatcga cgtcgatttt gcctgattgc tctttgctga ttttcatgct 1112761 gtggacgatt tcatcgaata agcggttaat ttgcgtcatt ttttctttac tttcgctgac 1112821 tagctcattc acgtctttga tatgcttgga tacaatgttg atttgtgtat tcgtattgtt 1112881 cacaagctca gaaacagtag agacggtttt tttcgtatcc tcagaaagct tccgcacttc 1112941 atttgccacg acagcaaagc ctttgccgtg ttctccggcg cgggcggatt caatagatgc 1113001 attgagcgag agaaggtttg tttgttcagc tatgcctgtg acgatgccga agattttttc 1113061 aatttgctgc gcgatttcat ccagcttgac catttctttt tcgatttgga caaggcttgt 1113121 gtcaattttg ttcatctgtt tttgctggac ttctagctct ttttttccgc cgatcgactt 1113181 ttcttcaaca gtgctggatg ttacagtgcc ggctttggat gcttgagaaa tgccttcaga 1113241 tttgtccaca agctcttgaa ctgatctgct tgtttctgaa aacagattgg caatcgatcc 1113301 agaggtttct tgaattttct gatgaagaag gtttttcttt tcttcttgtt catcacgggt 1113361 ctggttgtac tcgctttgaa acgcttcaag gacaagctgc tgttctaagt tcaagatttt 1113421 tgttgttgct ttaatggctt ttagcagttc ttgctgattt gtaatggacg cttcataaat 1113481 gtcaatcatt gacaaaagga gctcttgaaa cgcacccata taccattttg gcaaaaggcc 1113541 gattcttaaa tggatggagg cgattcggtt acgcttttca ataaattcat catcgataac 1113601 gcctgcaaac atttcctgaa tatgccgttt taacgtttgt tttaagcggt caactgagct 1113661 gtgatcatta atgatatcca tcaatgagct ttcatggtca aggtttttat aaaacgcatc 1113721 gacgatattt acgatatttt cttgaatgag tggctgaagc tgctctaaca cataaagctc 1113781 agcatctccc aacctgacca ttttgagctg ttttttgaca tctgcatgtt tgtttgtgag 1113841 ctgaatgcgg tttttttgtt gtccgtttga atctgaaaag taagctgttt cttgttttct 1113901 gtctttttta aataacaata caatgatccc ccttgggaaa aatataattt ttactttttg 1113961 gctttttaag cctttttctt ttttatcggc caagggaaac atgaatgaag ctgcagatga 1114021 aaaatatttg aaaaaacgtt cattaaaatg aacggtttaa tcgagatcta tttgttttaa 1114081 tggtttaatg gccggaccct ctacaacttc gccagatggc ttaaagcgtg atccgtggca 1114141 cggacaatcc cacgtatgct cactgtcgtt ccactcgacc tcgcagccta aatgggtaca 1114201 agtcgtatca acgagatgga ggcagcctgt ctcatcacga aatgctcccg ctcgcctgcc 1114261 gtttatggtg acggctttcc cttctcctgg cgaaatgtct tcaaattgga catcaggctt 1114321 ttcaagcttt ccttttatca aatgcttggc gacatctgca ttgtaggaaa tcactttctg 1114381 caacccggga ttcagatgga aacgggacgg cgtgaaaatg ctttcgtatg ggttttcttt 1114441 tttctccaca aggtctgaca ataaagtggc tgcgactgct gaggacgtca tgccccattt 1114501 tttgaacccg gtcgctacta gaatattgtc ctcattttcc gacatcggcc cgataaacgg 1114561 gattttgtcg atcgtcacta gatcttgggt ggaccaataa tatggaatgc tttcgatgcc 1114621 gatggtgctt tcggccagtt gtctcagtgt ttcataatgt gtagacatgg cttttccctg 1114681 gcctgtttta tggcttactc cgctgaagag aatcagcttt tcaccgttta caaccgtata 1114741 gcggagcgcc actgacggct gatcgatact caaatacatg ccctcgggat actcgatctt 1114801 cggcttgatg gcaaggacat aagatctgtc ggagtacatt ctcgcagcat ataatccgcc 1114861 tccgtcataa aaagggaagt gggaacagca tatgataaag cggctcttaa tggcgtgccg 1114921 gctttttgtt accacttcgg gcctttcgcc ttttttgata tcaagcgcaa cggtctcttc 1114981 ataaattcgg ccgccttttt gaacaatttg ctccagaagc gcttttaagt attgaagcgg 1115041 atgaaattga gcttgattct tcatgacaag cgccagctta gaacctaagg gaattggaag 1115101 atccttgata aggtctcttt caattccgag ctttgtgtat gcctcatgct cggtgtggat 1115161 tttttgaaca gcgttttcat ttgccgtata aagatatgcg tcttgctcga tccattcaca 1115221 atcaatttga tgttcatcca caatgccttt tatgtaatca attgcgtttt ggtttgcttc 1115281 ataataaagc ctcgcatggt ttaatccgaa atggcggata aattcgtcgt atatcatgtc 1115341 atgctgtgcg gtaactttag cagttgtatg cgcagtggtt ccgttaagaa cctgatttgc 1115401 ttcaatcaaa acgacacgga agcctctctt cgtaagttca tatgccgttg tgattcccgt 1115461 aatcccgcct ccgataatgg tgacgtcaca ttcagtgtcc tcttgaagcg caggaaaaga 1115521 aggcaggtca gttgatgttt tccagtatgt ttcaggtgct tcctttgcaa aatgttgatt 1115581 agccaagccg ttatacctcc aatcagattt attcttaatt tttccatatt ctatcttttc 1115641 atacatagga agcaggcatt gttcataaca taataaggtt gaaaaggagt gatttcattg 1115701 gcgaatcaaa aaaagaaaac attaccgcct cagcaccaga accagcagcc tggttttgaa 1115761 tatctgatgg acccgcgtcc ggtttttgat aagccgaaga aagcgaaaaa attagagggc 1115821 aaaaccgcta ttattactgg aggagacagc gggattggac gcgctgtctc ggtgttattc 1115881 gcaaaagaag gggctaatgt ggtcattgtg tatttgaatg aacatcagga cgccgaggaa 1115941 acaaagcagt atgtagaaaa ggaaggggta aaatgcctgc tgattgcagg agatgtcggg 1116001 gatgaagcgt tttgcaatga tgtggtcggg caggcaagcc aagtgtttcc atccattgat 1116061 atattggtta acaatgcagc tgagcagcat gtccagccca gcattgaaaa aatcaccagc 1116121 caccagctga tcagaacctt ccaaacaaac attttttcca tgttttactt aacaaaggca 1116181 gtgctgcctc atttaaaaaa agggagctct attattaata ccgcttcaat taccgcctat 1116241 aaaggcaata aaacgctgat cgattattca gcgacaaaag gcgcgatcgt tacgtttaca 1116301 aggtcccttt cccagtcgct tgttcagcag ggcatacggg tcaatgcagt ggcaccgggt 1116361 cccatttgga caccgcttat cccggccagc tttgccgcaa aagacgtgga agtgtttggt 1116421 tcagacgtgc cgatggaacg cccggggcag ccggtcgaag tggcgccaag ctatctatac 1116481 cttgccagcg acgattccac atacgtcaca gggcagacga ttcacgtcaa tggcggaaca 1116541 attgtgaacg gataataaaa agccaatcct tgaaggattg gcttattcgc tctgcttgag 1116601 cgctgcatat tctttagaga gcgtaagaaa cgcatcttta tctttttcgt ccaaggcttt 1116661 gttaatttgg tccgtcagca tggcaagccg acggttatac aaggattcat cgagcaccat 1116721 ttgaatgtaa atatccgtca ttgtgacatc gaattctttt gttttttgcg tgttgcggga 1116781 cttcatgagc tcagtgtacg attttttctc tttcataaag aatcccccca atgccttttt 1116841 tatagtatat ggataacggt cgaaaaaatc aataaatttt tataattttt agacaactaa 1116901 tacttggcaa tctatcgaca tatcctgcaa aatgccgtaa accggcaagt cttatgaaag 1116961 taaaatcggt ttattactag tcatttagta ccattaaata tcattaaaag atgattttat 1117021 cttaaatgtt aaaaaaacct gtcgttttac aaaaacagat gatagattat tagtataaat 1117081 tttgcagaaa aaggatggag gccataatat gagtcagaaa acagacgcac ctttagaatc 1117141 gtatgaagtg aacggcgcaa caattgccgt gctgccagaa gaaatagacg gcaaaatctg 1117201 ttccaaaatt attgaaaaag attgcgtgtt ttatgtaaac atgaagccgc tgcaaattgt 1117261 cgacagaagc tgccgatttt ttggatcaag ctatgcggga agaaaagcag gaacttatga 1117321 agtgacaaaa atttcacaca agccgccgat catggtggac ccttcgaacc aaatcttttt 1117381 attccctaca ctttcttcga caagacccca atgcggctgg atttcccatg tgcatgtaaa 1117441 agaattcaaa gcgactgaat tcgacgatac ggaagtgacg ttttccaatg ggaaaacgat 1117501 ggagctgccg atctcttata attcgttcga gaaccaggta taccgaacag cgtggctcag 1117561 aaccaaattc caagacagaa tcgaccaccg cgtgccgaaa agacaggaat ttatgctgta 1117621 cccgaaagaa gagcggacga agatgattta tgattttatt ttgcgtgagc tcggggaacg 1117681 gtattagaaa aataggaagg agctgaccga acagggcagc tcctttcata aagctatgcc 1117741 gtcggaattc ctccggtgat gccatatacc tgagatgtca catagcttga attctctgaa 1117801 gctagaaata cataaacatc ggccaattcc actggctgcc cagcgcgatt taatggagct 1117861 ggcggcgtgc cttgtccgaa tttcgggatg ttttccgtcg gctgtccgcc ggaaatttgc 1117921 agcggtgtcc aaattggtcc gggcgcaact gaatttactc tgatgccttt ggaagcaagc 1117981 tgttttccca gtccgacggt aaagccgata atggcgtttt tcgttgctgc gtaatctaac 1118041 agcatcgggc ttggattata gccttcaact gaggtagttg tgataattga agctccctcc 1118101 ggcaaatacg gaagcgccgc ttttacaacc cagtaaaggg aaaagacgtt cacttcaaat 1118161 gttttataga tttgttcagt aggcagatct tcgatgtttt cgaccgcttg ctgtttgcct 1118221 gcaacgagcg ctagcacatc aagtccgccg agttcgtgat gcgactgttt gactagatct 1118281 tggcaaaagg attcgtcgct caagtctccg gggatcagca ctgcttttcg gccttctgct 1118341 tcaatcagct cttttacctc ttcagcatct ggctgttcct cgggcaagta gttaatagcc 1118401 acatcggcac cttctctggc gtaagcaatt gcggcagcgc ggccgatacc ggaatcgccg 1118461 cccgtgacaa gcgcttttcg acccgttagt ttacctgatc ctttgtagct tttttctccg 1118521 caatcaggga caggcttcat gttcttttgc aggcctggcg gttcttgata ttgttcggga 1118581 aattcatcat gaaaaaatgc ttttatagga ttcgtaagat ttgaatcaga catcagcaac 1118641 gctccttttc tgtttggtgt acattcgtat gtgtacccct gagcataagc agaaaaacat 1118701 gttttggcag tttgaatagt gaaggaaaaa gaaaacaaga aaaaacaaag ccttcttcca 1118761 tatttatctt gtcaaataag actatatgaa ttatgataaa ttcgagctat aaatcaacta 1118821 aatattgggt gttgggagag tgaatcgtca tgaaaaaagc ggcggcggtt ttgctgtcac 1118881 tcggtctcgt tttcggtttt tcatacggag ctggccatgt ggcggaagcc aaaacaaagg 1118941 tgaaggtcta taagaactgc aaggagctaa acaaagtata caaaggcgga gtggcccgca 1119001 catcgaaggt gaaaaacaaa ggcggaaaaa cgaagtacaa gccttacgtt tctaaggcac 1119061 tttacgatgc caataaaaac aaagaccgcg ataaagatct tatcgcctgt gaacggtaaa 1119121 taagaaaaag caatctggtg tccagattgc tttttttatg cttaggccgc ctgatcggcc 1119181 gcagcgcttt tcgccttcct tgtcataagg ctgactgcca tcatgaccgt gatattcaaa 1119241 agcagggcga cgatgccgac attcaagtct tttgcggctt gcggcagagc cggaaataaa 1119301 gtgccgatcg tcgtttccgt cattgtaata taagtaactg ctccgacacc tgcaataatg 1119361 ccggcgaaag ctccttgctt tgtcaccata ttatgcttga gcaggctgaa caaaagggcg 1119421 gggaatagct gtgtgacaag gctgtagccc atcaaaagca gcgtaacgat ggtattcccg 1119481 cctttgaagg taaaatacac cgaaatcagc gcaatcaccg gcactaaaaa cttagcaagc 1119541 gccgatactt gctgttctgt cgtgcggggc gcgattacct tgtacacatt ttttgcaaac 1119601 agtgtggagg cggacattaa gatcatagac cctggcacaa gtgctgtcag cagtccggca 1119661 gcaccgataa ttccgacaaa ccaagggtca aatgcttgca gagacagtct caaaagcgac 1119721 aaatccccgt ctgcgccatt cagatctgga acttgcagga tagccgcaaa gccgacgaaa 1119781 aggacgaaga gcaggaccag ctggtacaaa ggcatgatga tggcgttttt acgaaacact 1119841 tttgggtttt cggctgaata cgaagcggaa aacgtgtgag gccacatgta aaaaccaagc 1119901 gctgtcaaga gtacggttga actgaaccag gccacacttt gtcccgattc ggggagcgta 1119961 agaaagccag gctttgccgt ttcaatctgc tgaaacatgt cttgaaatcc gccgtagtaa 1120021 tgaattggca aatacacacc taaaaacaga acgacaacca gaatcatgat gtccttcaca 1120081 accgatatcc aggcagaccc gtgaatgcct gaaaccataa cataaaccgt gatggaaaca 1120141 gcgccgatcc agatggcagc ggtcggggtg attttgccgt acgaggtttc cgatacaatc 1120201 agcccgaggc ctttcagctg cagtacaaga tagggaatga gtgcggcgat gccgaccagt 1120261 gaaacgagaa tgccaagcag cggactgttg tatttttttg tgaaaaaatc agactgcgac 1120321 atcagtttat gctgtttcgc gtacgtccaa actgctggaa gaagccagta agaaaggatg 1120381 taggccagac atccgtaggc gatgatataa aaggctggac cgccttttcc gtaggcccag 1120441 ccgctgccgc cgagaaacgt aaaagtagta taaatttcgc ctgccatcaa aaggaagacg 1120501 aaaacagttc cgaagccgcg ccctccgacc gtccactgct ccaggttcat gtcttttcct 1120561 ttttgggcgc gtataccgag aaaaatactc aagagcagga caccgaagat gatgatgaga 1120621 gctgcattca ttctgcttcc tcctttttat tttccttgtc gaggacatac acaatcgcca 1120681 tcagcgcaga ggtcaaaaga gcccacatca caatataggc aagaataaac ggcatgccga 1120741 acacataggg ggtcacctta tttgcaaaag ggatgccgag taagattccg ataaagggta 1120801 aagcggcaag aacgtgaatc agtttcatag aatcctcctt ctatttagga ttgaggtgta 1120861 caagcctaag cgtactgaaa atgatgtcgc agatatcgca gcacatgtca ttttttggag 1120921 tgaaaggctg tggttcgaat tataaataaa tttattttgt ttgtatagtg tgaattgtct 1120981 gaaattaatg ctctgaatcg cccgaagagg gaacgggcag tatgattcaa aaggctcaga 1121041 gtctgtctgg ggcaaataga tagtatgtta ataattcgct gacctgctca cggattcgcg 1121101 gattaaaata gcgatggttt tcttcataac cgtcgatgac aaatgtatag agtgtaaagg 1121161 cctcatcgcg ttccgtctcg cggattgcaa tttttctttt cctcagttct tttctgacct 1121221 ccatcaaatc cttttgtgct atttttaatg attcgctgat aagctgttta taaggatgct 1121281 tcaattttaa tgtgctttct tcaattccgg cgagatcacg gttaaaaatc gtaatggcca 1121341 tgggcaaaaa gagagcccgt tcaattaaat cgtatatttc ctcctgcaga tttggcatat 1121401 tgactccttc tttctaaggg aacgtttgtt ctatttgtat tctatatcgg ctggtgaaat 1121461 gtttcaagac agaaaaaatc accaaaactt tttagttttc tgctgataat gtgtagaata 1121521 aggatagaca aacccggtaa ggagtataaa tgttggagca ttttttatcc tatttgacac 1121581 aagaacattt aactgaatta tttcaaagct atagggcttt cggtccgctc attgctgtgc 1121641 tgctgccttt aattgaagca tttctcccgt ttttgccgct gatcgtgttt gtggtggcga 1121701 atacgaactc gtttggcttg tgggaaggat tcatcctatc ctgggcggga tcaactgctg 1121761 gttccattct cgtctttttg attgtccgtc aatacggaca gagaaaattg cttggattta 1121821 tccgcagtca tccgtctgtc agaaagctga tgttatgggt ggaaagacac ggcttcggtc 1121881 ccatgtttct tctgctttgt tttccattta caccgtcagc cgcggtgaat gttgttgccg 1121941 gtttgtcaag gatcggaacg cggccgttta ttttggcggc agcctcgggg aagcttgtca 1122001 tgatttttat gatcagcttc atcggatatg atctgcacgc gctgattaca cagccgattc 1122061 gaacggtcat cgccgtattg gtgatcactg tcttatggta tgtcggcaaa aaggtggagc 1122121 ggtatctgca tgtaagagcc agtcagcgtg agcatgatgg agggagacag taacatgaaa 1122181 aaacggtttt ggtttcttgc cggtgtagtg tccgttgttc tcgccattca ggttaaaaat 1122241 gctgtcttta ttgattacaa ggtagaaggc gtcagtatga acccgacctt ccaggaagga 1122301 aacgaattgt tggtcaataa attttcgcat cgatttaaaa ccatccatcg ttttgacatc 1122361 gtccttttta aaggccctga tcataaagtg ctgattaaac gggtaatcgg cttgcccggt 1122421 gaaacgatca aatataaaga tgatcagctg tatgtgaacg gaaagcaggt tgctgagcca 1122481 tttttgaagc atttgaaatc tgtttctgcc ggcagccatg taacgggtga tttttctttg 1122541 aaagatgtga cgggaacaag caaggtgccg aaaggaaaat attttgtcgt tggagataat 1122601 cgcatataca gcttcgacag ccggcatttt ggtccgataa gagaaaaaaa tattgtcggt 1122661 gtgatttctg atgccgaata aaaagacgct aattgaagag gcgtcttttt gtatgccgtt 1122721 tggaaaaatg tgttgaagaa aaatttgtaa ggagctataa tcaaaattgt tacctgtgta 1122781 acaaaattta tatatttttt tgactggagg gccgttttta ttggtttttg ttcgtttttc 1122841 atgaaacaaa aggagtggtg aatgatgatg aaatatgaag cagtgattat aggaggaggg 1122901 ccggttggat ttatgctggc ttctgagctt gcaatagccg gagtgggaac atgtgtgatt 1122961 gaacggcttg aaaaacctgt tccgcattcc aaggcgttga cgctgcaccc ccgaacgctg 1123021 gagcttcttg agatgagagg gattttagag cggttcgtat ccaagggaag caagatacct 1123081 accggacatt tttcaatgct ggatacccgt ctggattttt caggcttgga tacgagctgt 1123141 ccttacacgc ttttgctccc gcagtccaaa acagaaaagc ttcttgaaga tcatgcacga 1123201 agcctgggaa cagaggtgtt tcggggtgcc gaggcgctgg cggttacgca aaacggggaa 1123261 gcggtccaaa caatttttaa ggatcgggac ggcagtgtac ggacgatcac aagcaagttt 1123321 gccgttgggg cagatggcgc cgggagtacc gtccggaaac aggcgaaaat tgagtttccg 1123381 ggaacagaca gcactgtcac cgctgcgctt ggggatgtgg tgctcctttc tccgccgccg 1123441 tcaggtgtgc tgtccctttg cacaaaagag ggcggtgtta tgattgttcc gttatctcca 1123501 gaccgatacc gtgtcgttgt gatcagccct tatcgcacac aaacgccgaa agatgtgcct 1123561 gtgactgagg aagagctgaa agctgacctc ctgcgaattt gcggaactga cttcggttta 1123621 accgaccctt cgtggatgtc gcggtttggg aacgccgcgc gccaagcgaa acggtatcgg 1123681 gacggcagaa tctttcttgc gggtgatgcc gcgcatattc attttccggc gggcgggcaa 1123741 ggactgaatg tcggccttca ggatgcaatg aacctcgggt ggaaactggc ggcggccatc 1123801 aaaggctctg cgccttcttg gcttttggac agctaccatg atgagcggca tccggcagcg 1123861 gaagggctcc tcagaaacac ggaggcacag acaaagctga tcgatttcac tcaagcaggc 1123921 ctccatttgc gaagcatgat gtcggagctg ctggccttcc ctgatgtgaa tcgatatgta 1123981 gcggggcaaa tttctgcgct cgatgtcaga tatgaagctg atcgtaccat gccgccgaat 1124041 cgtttgaacg gggcaaggct ccctgacatg aagctgattc tttccgacgg caattcggaa 1124101 cggctgtaca gctttctcca aaacgggaca ttcgttttgc tgtcattgag gcaggaagct 1124161 gatgatcata tcgaagtaaa aggcttacgt acggtaaccg cctcgcttgc agaaccgaat 1124221 gaaaagttgc ggaatgtgca taccatattg attcgtcccg atggacatgt agcctgggcg 1124281 gtggatgcat cagcgcccga ttgttccgag gtgattcaaa aagggatcag ccgctggttt 1124341 tccgtcacca gccgagtata attcaattcg attgtttcat ctgtaacaaa acggtatgat 1124401 agaagaaaca atcgaatgaa aaaggatgga aaacccgatg aacacagatc atacgaaacg 1124461 caatcttttt gaattgtatg cggagctcat tcatcagcag gagaaatggg aggggcttat 1124521 taaagccttt ttatctgacg aattgaggaa gctggatgta gagcacggga gtaaatctca 1124581 attgacgatg acagaaattc atgttctatc ctgtgtcggg gacaatgaac caattaatgt 1124641 cacgtcgata gcagaaaaaa tgaatacgac aaaagcgact gtatcacgca tcagcacaaa 1124701 attgctcggc gcaggcttcc ttcacagaac acagctcagc gataataaaa aggaggtcta 1124761 cttccgattg acgcctgctg gaaaaaagct gcacagtttg cacaaatatt atcatcagaa 1124821 ggctgaacag cgttttctgt cattttttga ccgctatacc gaggaagaga ttctttttgc 1124881 ggaacggctg tttcgggatc tggtgacaaa atggtatccg tcgtcagaag aaattgaagg 1124941 ggggcttcct agcattttta aataaaaaac acgcactgcg gtgcgtgttt ttcgctttgt 1125001 ttctatcttt ttcaaggctg taacgtaaat cagatttcct cttgaagaat gaaattcaag 1125061 atgttcagga atttgcactg cttatacgat atgtctatta gtatctttat tttatacgtt 1125121 ttctactgtg tttttgatgc tttgttttca agtgaaatag ggtcttctgt tttagttctc 1125181 ctaatcttta cagaaatacc tactagaatg accgccatag ttgtaaatat tcccatggtt 1125241 aataagatcg tatcctggtt taaactccat ccaattaaga aagagatgat cgctcctccg 1125301 aaacttgccg aggcaataaa taaacttgta acttcgtcaa cgtacttctg aataatgatt 1125361 gatgctagtg ttaaagcaat gggaaatatc cccgctatac ttaggccaat caaaaatgta 1125421 ccactcaatt gaagtattgg gttacttata taagagaagg caatcaacaa aacaattaaa 1125481 caactacagc taaaaagaag gtatttggaa aaatcaagcc ttctacttac gaaaccaatc 1125541 aatattcttc ctatgatgat ccctacccag aaaaaggaga cacttataag actaatttgt 1125601 tcattgtctt ggtttatcat gattgaaggt aaaaagttgg caaaatttgt ttcaattcca 1125661 gcatatagga aagcgaaaaa tacaaaaaag cctaattgct ttgatttttt tctatctcct 1125721 ataaagtatt gaaatgctcc tccatctgga aaggtcactt gttggttagc attcttagcg 1125781 tactctcggt tcttagacaa gaaaattaac caccctacga ataggacgaa taaaaaggtg 1125841 aatatacagt aatatggtaa aaaccagtta ttgatatcta tgaaggaatt aattaataat 1125901 gggaaagata aagcgcctaa tccaaagaga acttccagct tactcatttt ttctgcatta 1125961 ctttcgaaat tagcaataac aaatgaacca actgtcgttt ctaatgtgcc tgctccatat 1126021 cctaagagaa aagccattac aataatataa taccaatcct tggttagaaa aaagatactt 1126081 aacgctacaa gcattattgt caaagctaaa gtaagtgtcc taaaatgact gtatttctta 1126141 atcattaaag gtgcgattaa tactccgctt agaaatccgg taaactggaa gaagattatg 1126201 accgaaatat catctgttgt cttgttaaaa gcctctaata aaaatggtgt caaactccct 1126261 gttgatatat ggataatacc tactgtaaaa aagaaagcat atccaaataa atatgtccct 1126321 cttaacattc attacacccc tatatgaaaa agcaggaaag taaattcctg cttttttagt 1126381 aacttctctc tttgaaatac tagttgactg ctgaaacaga catgggttga gagttgctgt 1126441 ctttctcaaa gaacatttct aatacttcct gagatctaaa accatcacta aaagaaggga 1126501 tctcaaccca atcattctga gttgatgcaa tccaattgat taactcgctt ctaaaagaat 1126561 cagcccatcc ataaaactcg tttggcggat cgtttaatag gctttgcggt actgggcagt 1126621 ctaccacgtt caagccatct atgagcttgt aaacgtgagg attacctgtg tggtatttaa 1126681 actctttttt gtgtccaact acctcaatgc taaaaccaca gtcttcaggt acagaacact 1126741 ttgatgtgat gatatttaca aataccttgt tcttcagctg gccataaatt tctgcatagt 1126801 catctacaag tacctgttta tcctcttttg tttttacatt tgtgttcatc tttgccctta 1126861 ctgattctgt gatgaaatca ctctcgaaca aataccatac catgtcaata aggtgaatac 1126921 ccagatcccc caatgatcca ctcgtcttct tactattagc gtcatctctc caagtaaact 1126981 tcttacgtct aagtgcacta tttttcttga agtgtacttt tatggacagt atgttaccta 1127041 gttcattatt gataattaag ctttttaaga tatttacgta agataaatat ctataattaa 1127101 atcccatact ggctcttacg ctcaaccttt cagcagtatc tttcattatg cttgcttctt 1127161 caagagaaat agccataggc ttttcacata atacatgctt atgttttcct aatgcttgca 1127221 aagcatgttc tttatggcaa aagtttggtg atgctacaat taaaccttct gaggcatcaa 1127281 ttagttcatc tacgttttca aatgacttcc cgccgaaagt tttcacaaag ctttccgcat 1127341 tttgttgatt tatgtcatat acccctacta actctgcatt ttttattgta gataaagcag 1127401 ttgcatgcgc tcttgcaata ccacctgcac ctatgatgcc tatcttcttc atttttattt 1127461 cctcctcatg atccaattaa tttttttaag gtattagtaa ttccttttga gtactcacta 1127521 tcagttataa ggttgtgcaa gtttttggct tcctgtgttg cattttttag cagatatcca 1127581 ttccctactg tctgtaacat acgaacatca tttccactat ccccaaatgc gatagctctt 1127641 tcggtattta ggttgtattt ctctaacata aacgttacaa tttcattctt tcctgtccct 1127701 atggggataa aatctacatc atagctgtct tctggatcgc ctgctaaggg attacaccga 1127761 tttatattta ctgaaacgcc gtattcttcg cagatttttt caatagctaa taggtttttc 1127821 ttgtcgttta tttcatcttg ttcctgatag tagaagttat gcttataccg tgactttcct 1127881 aattgggttt gaggattcaa aagaatgtta tgattttcat gcagctgttt cacaagtttt 1127941 tcaacctttt ctttactaaa cccttcattt atgcgactgt tccacttgtt atcttgctga 1128001 ccgaagttat gctctgaaaa gtacgtaatt tcagttccaa gatcactagc tataaaatgc 1128061 ggaaaatatc taaattttcc tcgtcccatt ttatcgagaa tagattctat actgctccca 1128121 gtaacccatc cgattattag ctccccatct ttactttttt gttctagata gtcttcgagt 1128181 tcatagatgt cttgttgctt ttgttcgtcg attgtatgcg gaaaatacgt ttcatcaaaa 1128241 tcacaaaaaa caatatattg aggatgttca accgtggata acgttttata ctccgatttc 1128301 ttgcttaata acatgaaaca gtccctccat tactctgtct tgttcttcta aagtaaatga 1128361 cggatataaa ggcaaatgca gtacctgact atgagccttt tccgtatgaa ccaattggag 1128421 tcctgcatac ttgtcctgta ctaaaggagt tttttgcata tgagaaagta ttggataata 1128481 tacatctgtt tgaacaccaa aatcttcatt taatttagtc atgatatctg ccctatcttc 1128541 tgttcttacc ttaataggaa acagatgcca tacatgatct tcacttaatt ctggtaattc 1128601 aatatagcct ttattctgca actctgctaa ttgggtaatg tatctatccg ccaagaacaa 1128661 tcttttgaag ttgtttaatg aaaggtactt cattctctct aaaccaattg ctgcctgtaa 1128721 attgtccatt tttgaattaa atccaaaatt gatgactttc ttatttttta catttacttc 1128781 aaaaccgtga taactaaatt gaatgcattt tttagcgagt tcttcattat cagttgctat 1128841 tgccccagcc ttgccacata caccaaaatt cttataggga ttaaaactta atgtagtgat 1128901 gtctgcatac tttcctaagt ctgtcagtcc aattccttgg caggcatctt caattacttt 1128961 taatttataa cgatttgcga tttgacggat atgctgcatg tctgaatgtt ttccgtataa 1129021 atgcacaggt agaataaact ttgtataagg agttattgct tcttcaattt tgtcaggatc 1129081 gatgcagaat gtttgtgggt taatatctac atagatagga acgcctcccg aagctaacac 1129141 agcattttca gtagctgaaa agctattagc cggcatgata acttcatccc ctgggtttaa 1129201 ccctaaagcc aataaaccta tcataatagc atcggttcca ctgctggttg caattacata 1129261 ccttttatgt aaatatgtag ataaaacttt ttcgaattgc tctaaatagg gaccactcgt 1129321 aaattttcca gttggcaaaa cttcagttaa tgtatttaag atatcttcca cttcatcatt 1129381 ggttattaat ctgtctacag gcaaaaaagg gactttactg atttcacgat ttttttgata 1129441 gttgaaaagg tcatgttcaa tatctatctt ttcttttaat acttgtttcc accgctcgtt 1129501 tacaatactg tcttcaataa caagttcttt tccttgtacg tcacctttta agtgttttaa 1129561 tagtgacatg ttttctttgc ttttacctga aatcttaacc tgtttttgca tgaacagtac 1129621 ctccaatgat tttataatct aaaaatttat tacaaattta tcctagtttc tgaaatcggt 1129681 aacatgtcaa caactttttt aaggaaggga aaatatgcct acaattgatg aaatagcaaa 1129741 attatgcaat gtgtctaaaa ccacagtgtc aagagtattg aataatcatc cttatgtgtc 1129801 gaaagaaaaa agagatatga tcttaaaggc tattaacgaa cttgactaca ctcccaatta 1129861 tttagctcgg aattttagga gaaataagac acaaacgata gctttatcgg ttccgagtat 1129921 cgaccatcca ttttttgctc aattaataaa aggggtctct catgaagtac tgtttaagaa 1129981 ttacaaggta attgtatttc agacctttta tgacaaacag acggagctag aattactaga 1130041 gttattgaag cataaagaag tggatggcat tattcttggg actttagaaa atgaatggga 1130101 tcagatatcc cctttcttaa agtatggtcc tatcttatta tgtaatgaat atcatcactc 1130161 agcggacatc acgataattg ggtatgatga atttgaagcc gcatacatgg gggtagtaca 1130221 tttaattgaa agagggcata aaaaaattgg gttttgtttt gatactccat atagcgaagc 1130281 tcaatgtcag aggaaagagg gttatttgaa agctttacaa gattacaatt tacatcatag 1130341 aagcgaatgg atattcggcg aaatgtttaa tatcgaggat ggctttcgtg tttttcataa 1130401 gataaaggat ctaaaggaca gaccctcagc aatatttaca ggaaatgatc aagtcgccgc 1130461 agggattatt aaacaggcga tgaaaaatgg ctttaaagtt ccagaagact tagctgtaat 1130521 tggttttgac aaccaattga tttgccaagt cgttactccg accataacaa caattgatat 1130581 ccccgtaata gaattaggcc aacaggctgt gttgaaaatc atcgagtcca tttcgggtaa 1130641 tgcctcttta aacagaagaa ttattaaact gccaacaaag cttattataa gagaatcaac 1130701 gtaacgatag atttcccttt aacattttat atctttatat aagaaaaaga ggttattcat 1130761 tttaacctct ttttcaatcg taagtcgtca attatttctt tcatttcacc ctctggcagc 1130821 actcacttca aatctgatcc attaacaacg aaatatccgc ttatatttcc tcatctcgat 1130881 ggtttgcgaa ttaaaagttc ttgaaccctt ttttcaacta ggcactactg ccgctgattg 1130941 agctcttttt gtcttttttt tcaccatgaa gatggtgaag caggcgataa aacggcggca 1131001 gcagggcaat aaccagaatg acgcgaatga cctgaaccgc aacgacaaag gtggaatcag 1131061 catgtaaggt aactgacgtc gtcgccatct ctgcaatccc gccgggcgca aatgccagaa 1131121 cagaagtgat gagcgaaatt cctgtcagct cggaaacgat cacggcgctc aaaaacattg 1131181 ctgcgattaa accgacggac gagacaaacc cgacgatgat aatacgggtg acgccggcaa 1131241 acatgctttt gtacatctta gagccgatcg ttgccccgag aaatacttgt gatacatggt 1131301 tagcttgtga caaccaccat gccgtcatgt cgtgccctgt caccgcagct ccgccaacat 1131361 gtacaattgc tacaccgagc atgctgccga gcagccatgg agctggaaat tttaaaaatt 1131421 tcgcagcttt gcaagctccc caggcagcga gaataagaat gacggtccac aaaacgggag 1131481 cgagcctaaa atctgtcgtt gcagaagaaa tcgtctctgc tgcggcactt gcggtacgat 1131541 cttgttttgt atagatcaga atgactaaaa acggaatgga aagcaccacg agcagcacac 1131601 gcatcatttg aacgaggctg actatagcgg tattggcgcc tacttcctgt gcgatgctcg 1131661 gcatggcgga aagtccgccg ggagcggtgc cgacaaagct agtcatcata tccgttttgc 1131721 tgaaacgcca aagcacatat cctgacagca tggccagcag gatagacaat atcagcataa 1131781 cgccgactga aaaccaatgg tctttgagaa cagagagaac ggataaattc agcttttggc 1131841 ccaattcgat gccgaggatc atctgcccga gggcgagcca tcgtcggtta attccttttt 1131901 ggtctggtgc catcatcagc catgccggcc gtatcatggc gaggcagcag gcgacaatca 1131961 gtgttccgat catccatcca attgatattc cggttaatga aagaataaac cccccggctg 1132021 cactgattgc gataaaccat agatctttga ggagattttc gtctttcttc aatgtaaaac 1132081 ccttcttcct ttttcacgta acactccaat tgttcacgta gtgaatgtat ttattactat 1132141 agtatatttt tgttgataaa gaaattatga attattttct ataagcgatt cacttttctt 1132201 atgaccttgt gttcgagctt ttctattgtg taagtcagag ataaacccgc tgtcagcaga 1132261 cacacggcaa gagcgtaaaa aatcacttct ccgccaaatg atgtcaggat cagcccgcct 1132321 gccagcggtc cgattgagcg ggatatatcc caatgcagac catagacagc ataaaaccgg 1132381 cccagcaaat gaggcggcgc caatttcgat atgaaggtct ggatgtgggt tagcccgatg 1132441 ctttcaccaa ccgtcatcac cgctgccgtc actaaaagca ttgtcagaga ggttgagcat 1132501 gcaaagccgg ctgccgcaag ggagtagcaa atataagtaa tgaagaggat cgttttcatt 1132561 gaaagctttt cggtcccttt gacaagaggt acttggagaa cacagctgaa taaagctttt 1132621 gctgctgaat agatggtcag catggacaga taatcagaaa acatgttttt gctgaacagc 1132681 ctgtatgttg tttctgtttg tgcatataac atgctgatgg ggagagaaag cagcaaaaga 1132741 agcaggacag gcctgtatat tgtaaagctc gcggacattt tcggggtaac agctgggtgt 1132801 agcggctttg tctcaggcag tttcagtgca gcgatcagaa agtagataaa caatgctgca 1132861 gcatctaatg cgaatatcca cacggggtta tgattgtaca gcagcatccc cactagcggt 1132921 cctgccgtca gacccgtcga atagatcgca ttgatgaccg caaacacttc cgaacgtctg 1132981 ctttccggcg tgctttcagc gatttgggcg cgggaagcgg gaatgtacaa cgatcttccg 1133041 atgccattca tgacatagag aatagcgaaa acatacgcat gctcagcaaa tacaaaccct 1133101 gtcattgccg ctgattgaag aagcaatgcg gtcaaaatcg ctgtgcgccg cccaagccga 1133161 tccgtcaccc gtcctgcagc gagcgtcagg aaaatatcag caaatggctg aaggctgatg 1133221 atcagcattg gcatcatgat actgccgttt aattgttcat gcagatacag caccataaaa 1133281 ggtcccatca ttgcacctgt caggcttgtc agcaattcgc cgaaaaagcg gagccgaacg 1133341 ggagcggtat atctcgattt tatagagtga aaactggtca acatgtgatc gccgcctttc 1133401 gctgtttgat atagtagtag tgtatagaag gggcggcggc ccaaaaagtg aagaaaagaa 1133461 gagataaaag ttcccctttt gtcgggaggt gcggggattg aagctgatag agcactacgt 1133521 ggcgcttgta aaaacaggct gcgccgagta tgggcaaatg aacgaaatga cgctcactga 1133581 gattgccgac tgtttatttt gtacagaaag aaatgcaaag ctcattttac ataagctgga 1133641 gaacagcaat tggattatcc gggaaagcgg ggcggggcgc ggccgcaaat ctaaaatcgc 1133701 gtttcttcgg aggcctgagg aactgcttct tcaaactgca aaggaatata ccatgtcagg 1133761 aaagcttaaa aaggcaaagg agctgcttca gcagtatcag tccgcgtttc cagggcttca 1133821 aaacgaatat aacatgtggc tatcagaggt attcggattt gtgacggaga caggcgagaa 1133881 tggggcgaag gatgtcctgc ggctgttcat cacgcctgaa tctgtcagca gtttggatcc 1133941 atgccaaata tttttgcggt ctgagggcca tttcgtcaaa cagatatttg atacactctt 1134001 cacgtttgat tcggatatgc aggagccgaa gcctcatttg gttcatggat gggaagaggt 1134061 cggaaaaaaa caatggagat tttttcttcg aaaaggtgtg ttatttcata atggacagcc 1134121 gctgacatcg cgggacgttg cgtttacatt tcagcgcttt ttggaactgg ctgacaaccc 1134181 gtataaatgg cttctgcacg gagtgaaaca agtcttagaa aagggccctt attgtgtgga 1134241 gctcatactc gataagccga atgcgctttt gccgtatgct ctttgtgatg aacggctgtc 1134301 catactgccg gcagaacagg gcggcgggaa aaatggaaca gggccttttc agatgaatca 1134361 gcaacatagc gggatgcttg tgcttgaagc caatgagcgc tacttcaagg gacgccccta 1134421 tttggatcgc gttgagtttg tgttttctga gcaagccgga gagatgaacg gttttaccat 1134481 tcaagaaaaa caaacatgtc ctgagcagca aactgtcttt gatgagcggc atgttcagta 1134541 tttgtcgctt aatctgaaaa agaaggggcc tcttcagcac cgaagcttta gaaaagcgct 1134601 ccggctgctg atttcctctg aacggctcgt tcgtgaagcg ggagggcacc gaagaattcc 1134661 ggttacgtcc tttttgcatc cgagtccttt tgagtgggag ggcgtttcgc catctgaatt 1134721 gttgaaaaaa agcggatacg agggcgaaac aatcgtgctt tatacctttt cggaaacgga 1134781 tcatcgtgag gacgccgaat ggattcaaaa tatttgcgcc cagcacggta tcaggcttac 1134841 acttcaattc tgtgatgctg ctgatctgcg acggccggaa atcgtgcaga tggcggatat 1134901 cattcatgac agtgcgacgt tttatcaaga cagcgagttt ggttttctgc atttgctgct 1134961 gtcggagaac agtttcttgt atcagcatct atctgaaaag ctgacacaga tttgctcagg 1135021 aatgacagag cggatgtttt ccatgcctga ccgctgttcg agaatcaaca tcctgcgtga 1135081 cattgaccgg cagatgatac aggagctgaa cgcgatcccg ctgtatcaaa atgtgctcca 1135141 ggtgacatca agtaaaaatg taaaaggcct ggtgcttgat gaagagggat ggattgattt 1135201 gtactccgta tggctgtcca aataaaaaga gggttctttt ttgaaccctc ttttttacgc 1135261 tgccatgctg cggcattgtt cagcacaggt gaagcaggct ttcgcacatg cttggcaatg 1135321 atcatgatcg tgctttccgc attcagtgcc gcatgcttca caaatatcgg cgcaaagtgc 1135381 acaaatttct ttcataaacg ggctgtccgt ttgcatggct ttgaccgcca gcgcgcaaat 1135441 atccgcgcat tccctgtcaa gccggatgca tccgctgaga tgatgctgca cgctttcttc 1135501 caagcattta gtgaaacaat gattgcaagc cttcatgcaa tcgatgcaag cctcaataca 1135561 agcctcagaa tattgctcca tggttgattc cccctgtatg acagtatatg gttttatgtt 1135621 tcacggctgc atttgaaaaa aacaggggag tgtgttttta gctaagggga tatgtacata 1135681 taccctgaat gggtatatct aacgttccat cagatagtat aggaaccaga cagcgtgatt 1135741 ttgttcatca cgtgctgcgc gcgtaaagac gcctttcgct tttaagtttg acgtttcctc 1135801 ggccgcacgc aagtaaaagt cgacggtttc ttgttcatct ttaaaagcgg cgtccagtcc 1135861 tcttgtgaaa ttgtccgggc attcttccgt ttgtttcggc atgatgtgtt tgccggtaat 1135921 tgaaccatac agtgtggaaa attcacggag gtggcgaatc tcgtcacgcc tgatttcttc 1135981 aatctgtttt ctgacctcat cgctgtgggc gagttcggca agcttgcggt agcattgaat 1136041 agcactgaat tctccgttga tggccttctg caaattccga atcaaaacag gatcttcccg 1136101 gtatggcacc ggatagggat agtagctgta atgcaagggg attcaactcc attcttagga 1136161 attgggcttc tgtaaaagta tatgttgggc agggagagat gtgcggagat aatcagcttt 1136221 ttatatgtga aaaggccgtt tttaccaata gatcagattg gtcattttcg tcaacattcg 1136281 ataaaatata gagagataaa aagagagggg tcttctaatt tgggagcaga gtttttagta 1136341 ggcaggtccg ggagtggaaa aacgaagctg atcatcaaca gcattcagga tgaattgcgc 1136401 cgggctccat tcgggaagcc gatcattttt ctagtcccgg atcaaatgac gtttttaatg 1136461 gaatacgagc ttgctaaaac gccagatatg ggcgggatga tacgcgctca agtgttcagt 1136521 ttttcacgat tggcctggcg cgtcctccag catacgggag gaatgagcag gccgtttctg 1136581 acgagcaccg gcgtacaaat gctcctgcgg aagctcattg aggagcataa acaggagttc 1136641 aaagtctatc aaaaagcgag tgacaaaagc gggtttaccg cacaggttga gcggatgctg 1136701 acagagttta agcgctattg tctggaaccg gaggatatcc gccggatggc ggaaagcgga 1136761 acggcttccg agtatcgcgg agaacgtgtt ttatctgaaa agctccatga cttatcaatt 1136821 ctgtatcagc aaatggaaaa aagcctcgca gatcaatatc ttcactctga ggattatttg 1136881 acattgctgg cagagcatat cccgcttgcg gaagatataa aaggcgccca tatctatgtg 1136941 gatggctttt atcagtttac cccgcaggaa ttcagggtgt tggagcagct tatggttcat 1137001 gcggagcata tcacgttttc gctcacagcg gacaagccgt catatgagcg ggagccgcat 1137061 gaactggaat tgttcagaat gacggggaaa acctattacc gcctgcatca gaaggcgaag 1137121 gaactgaatt tggacattac gtataaagag ctgagcggga ctgagcggca tacaaagacg 1137181 ccggaattgg cgcatctaga ggcacagtat gaagcgcgtc cggccattcc atacgcagaa 1137241 aaacaagaag cccttactgt gatgcaggcc gcaaacagac gagctgagct ggaaggcatt 1137301 gctcgggaaa ttcacgccct agtcagagag aagggatatc gctataagga tgtagcaatt 1137361 cttgcgcgcc agccggaaga ctacaaggat atggtgaagg aagttttcgc agattacgag 1137421 attccttatt tcattgacgg aaaagcatct atgctgaacc atccgttaat tgaatttatc 1137481 cggtcgagcc ttgatgttct gaaagggaat tggcgttatg aagcggtgtt tcgctgcgtg 1137541 aaaaccgaac tgctattccc gctcaatgaa ccgaaggcca aagtgagaga acaggtcgat 1137601 cagctcgaaa attactgtat cgcctatggt attaaaggcg accgctggac aaagggcgat 1137661 cggttccaat acaggcgttt tgtgtcattg gatgatgatt ttgcgcagac tgatcaggaa 1137721 atcgaaatgg aaaacatgtt gaatgacacc cgcgattgga ttgttccgcc gctttttcag 1137781 cttcaaaaac gcatgaaaaa agcgaagacg gttcaagaga aggcggaggc gctctatcgt 1137841 tatttagaag agacggatgt gccgctgaag ctggatcagg aaaggcagcg tgctgaggat 1137901 gacggcagaa tcattgaagc gcagcagcat cagcaggcgt gggacgcagt cattcagctg 1137961 cttgaggagt ttgttgaaat gatgggagat gatgagattt ctcttgattt gtttcagcaa 1138021 atgatagaag ccggcgcgga gtcgcttaca ttttctctaa ttccgcctgc gcttgaccag 1138081 gtgtttgtcg gcaatatgga tttgtccaga atgtatggca cctcctgcac ctttgtgctc 1138141 ggggcaaacg acggcgttct gccggcacgc cctgatgaaa acggggtcct gtcggatgat 1138201 gaccgggaat ggctgaaaac gattggggtt gagctatcct caggcggacg agagcgtttg 1138261 cttgatgagc acttcctcat ctacatggcg ttttcaagtc cgtctgaccg gctttacgta 1138321 tcgtatccga ttgctgatgc ggaaggaaaa acgcttttgc cgtcgatgat cgttaagcgg 1138381 ctggaagaac tgtttccgca tcataaggag cgcctgttaa caaatgaacc tgaacaggtc 1138441 agcgatgagg aacagctgat gtatgttgtg aataaaagcg tggcacagtc ctttaccgcg 1138501 agccagctca ggttatggac tcgggaatac gacatcagcg acgtctggtg gagcacgtac 1138561 aatgtgctga tgagtgagca ggacaggctg caatcgaaaa agctgttctc aagcctgttt 1138621 ttccggaatg aagtgaagca gcttgaacgc agcgtgtcga gacagctcta tggtgaacgt 1138681 attcagggca gtgtatcgag aatggaaacc tttaacgcat gcccgttttc ccattttgcg 1138741 tcacacgggc tgcatttgaa ggaacggcaa ttcttcaagc ttgaagcacc ggatatcggc 1138801 cagctgtttc attccagctt aaagctgatt tcggacaggc tgcgtgagca aaagctggat 1138861 tggcgcgatt taacgaagga gcagtgcgag ctgttttcct atgatgcggt agagcggctg 1138921 gcaccgaaac tgcaaaagga aattctgctc agctcaaacc ggcattatta tgtgaaggaa 1138981 aaactgcaaa aaattgtgac acgtgtgtcc ggcattttaa gcgagcatgc gaaagcgagc 1139041 ggattcgtac cgatcgggct tgaactgggc tttggaggaa aagggccgct tccgccgctg 1139101 acctttcaac tgaaaaacgg ctgtacgatg gaactcgtcg ggcgaattga ccgtgttgat 1139161 aaggctgaaa gctcaaaagg cctgctcctc aggattgtcg attataaatc aagcgacaaa 1139221 ggccttgact tagcggaagt atattacgga ttggcactgc aaatgctgac gtaccttgat 1139281 ttatcgatta cacattcagc tgactggctc gggatgaggg cgacgcctgc cggagtgctg 1139341 tatttccata ttcatgaccc gatgattcaa tctaatctcc cgcttgggct tgacgagatt 1139401 gaacaggaga tctttaagaa atttaaaatg aagggcttgc tcctcggtga tcaggaagtg 1139461 gttcgcctca tggatacaac ccttcaagag ggacgttcaa atatcataaa cgccggcttg 1139521 aaaaaagacg gctctctcag atcagactca gcagcagtcg gtgaaaagga atttgatctt 1139581 ttgacaaagc atgtgcgccg caccttccaa gaagcgggcg aacaaatcac cgacgggcgc 1139641 gtatccattg agccgtacaa aatgaagaac aagacgccgt gcacatactg tgcgttcaaa 1139701 tcagtatgcc aatttgatga atcactggaa gaaaacgagt atcgcccatt aaaggctgaa 1139761 aaggacaaga caatacttga gtggataaaa aaggaggcgg atggcaatga acattcctaa 1139821 accggcagac agcacatgga cagatgacca atggaatgcc attgtttcaa ccggccagga 1139881 tattcttgtg gcagcggctg cgggctctgg taaaaccgct gtgctcgttg aacgaatgat 1139941 tcggaaaatc accgcggagg aaaacccaat agatgtagac cgtcttctcg ttgtgacatt 1140001 tacaaacgcc tcagcggcag agatgaagca ccgaatcgca gaagccttgg aaaaagagct 1140061 tgtacagcgc cccggctcgc tgcatattag acgccagctg tctcttttaa accgggccag 1140121 catttcgacg ctccattcct tttgcctgca agtgctgaag aaatattact acttgatcga 1140181 tcttgatccg ggctttcgga tagctgatca gacggaaggc gagctgatcg gggatgaagt 1140241 gcttgacgag ctgtttgaag acgaatacgc aaagggcgaa aaggcgtttt ttgagcttgt 1140301 tgaccgctat acgacagacc ggcatgatct ggatctgcaa tttctcgtta aacaggtgta 1140361 cgagtattcc cgatcccatc ccaacccgga ggcgtggctg gaaagctttg ttcatttgta 1140421 tgatgtatca gaaaagagcg ccatcgagga gctgccgttt tatcaatatg tcaaagaaga 1140481 tattgcaatg gtgcttaacg gggcgaagga aaagctcttg cgcgcgcttg agctgacgaa 1140541 agcgccgggc ggcccggcgc cgcgtgctga caattttctt gatgatcttg ctcagattga 1140601 tgaactgatt cagcatcagg acgatttcag tgaactatat aagcgggtgc ccgccgtctc 1140661 ttttaagcgt gccaaagcag taaaagggga tgagttcgat ccagcgctcc ttgatgaggc 1140721 gacagatttg aggaacggcg caaaaaaact gcttgaaaag ctcaaaaccg actacttcac 1140781 gcgaagtcct gaacagcact tgaaaagcct agccgagatg aagcctgtca ttgaaacgct 1140841 cgtacagctt gtcatcagct atggaaaacg attcgaagct gcgaaacagg aaaaatcaat 1140901 catcgatttt tcggatttgg agcattactg tttagcgatt ttgacagctg agaatgacaa 1140961 aggtgaacgt gagccgagcg aggctgcaag gttttatcag gaacagtttc atgaggtgct 1141021 cgttgacgaa tatcaggata ccaacctcgt gcaggaatcg attctgcagc tcgtcacaag 1141081 cggtccggag gagactggta acctgtttat ggtaggagat gtcaaacagt cgatttatcg 1141141 attcaggctt gcggagccgc ttcttttcct ctctaaatac aaacggttta cagagagcgg 1141201 agaaggcacg gggcggaaaa tcgatttaaa taaaaatttc cgaagccggg ctgatatttt 1141261 agacagcaca aactttttat ttaaacagct gatgggcggc aaaatcggtg aggtcgatta 1141321 tgacgagcag gctgagctga agcttggtgc agcgtatccg gacaatgacg agacggaaac 1141381 agagctgctg ctgatcgaca acgcagaaga tacggatgca agcgaggaag cagaagagct 1141441 tgaaacggtg cagtttgagg caaaagccat cgctaaggaa attcgtaagc tgatttcatc 1141501 gccgtttaag gtgtatgacg gaaaaaagaa aacacatcgc aatattcaat accgagatat 1141561 cgtgattttg ctccgttcga tgccgtgggc tccgcaaatc atggaggagc tgagagcaca 1141621 gggcataccg gtttacgcca atttaacgtc aggctatttt gaagcggtcg aagtcgccgt 1141681 cgcgctttct gtgctgaagg tgattgataa tccgtatcag gatataccgc ttgcctctgt 1141741 gctgcgctca ccgattgtcg gagcagatga aaacgagctg tctttgatcc ggcttgaaaa 1141801 taaaaaagcg ccgtactatg aggcgatgaa agactacctg gctgctggtg accggagcga 1141861 tgagctttat caaaagttaa atacgtttta cggacatctg caaaaatggc gcgcgttttc 1141921 gaaaaaccac tcagtatctg agctgatttg ggaagtgtac cgcgacacca aatatatgga 1141981 ttatgtcggc ggcatgccgg gcggaaaaca gcgccaggcc aatttgcgtg ttctttatga 1142041 cagggcgcgt caatatgaat caacggcatt tcgcggcttg ttccgtttcc tgcggtttat 1142101 cgaacgcatg caggagcggg gcgatgatct tggtacggcg agagcgctca gcgagcagga 1142161 ggatgttgtc cgcttaatga cgatccacag cagcaaaggg ctcgaatttc cagtcgtgtt 1142221 tgtagcaggt ctcggccgga atttcaacat gatggatttg aacaaatcgt acctgctgga 1142281 taaggagctc ggatttggca cgaagtatat tcatccgcaa ttacgcatca gctatccgac 1142341 acttccgctc attgcgatga agaaaaaaat gcgcagggag ctgctgtcag aggaattgcg 1142401 tgtgctctat gttgcattaa cgagagcgaa ggaaaagctg tttctgattg gctcatgtaa 1142461 ggatcatcag aaacagcttg caaaatggca ggcatccgcg tcccaaactg attggcttct 1142521 gccggaattt gaccgctatc aggcgagaac gtatctagat ttcattgggc cggctcttgc 1142581 caggcacaga gacttggggg atttggctgg tgtgccagca cacgctgaca tctcaggtca 1142641 cccggctcgt tttgccgttc aaatgatcca ttcctatgat ttgcttgatg atgatctgga 1142701 agaaagaatg gaagaaaaaa gcgagcgcct agaagcgatc cgccgaggtg aaccagttcc 1142761 cggctcgttt gcgtttgatg aaaaagcccg cgagcagctg agctggacct acccgcatca 1142821 agaagtgacg caaattcgga caaagcaatc agtttctgag atcaagagaa aaagagagta 1142881 cgaggatgaa tacagcggca gggcccctgt aaaaccggct gatggaagca ttctgtacag 1142941 acgtcccgct tttatgatga aaaaaggcct gacagcggca gagaaaggga ctgccatgca 1143001 tacggttatg cagcatatcc cgctgtcaca tgtgccgtcg atagaagaag ctgagcagac 1143061 ggttcacagg ctttatgaaa aagagcttct cactgaagaa caaaaagacg ctattgatat 1143121 agaagaaatc gtgcaatttt tccatacaga aatcggcgga cagctgatcg gtgctaagtg 1143181 gaaggaccgg gaaataccat tcagcttagc gcttccggcc aaggagatct atcctgatgc 1143241 acacgaggca gatgagccgc ttttagtgca gggtattatt gactgtctct atgaaactga 1143301 ggacggatta tatctattgg attataagtc ggaccggatt gagggcaaat tccagcatgg 1143361 atttgaagga gcggccccga tcttgaagaa acgatatgaa acgcaaattc agctgtacac 1143421 gaaggcagtg gagcaaattg caaaaacaaa ggtaaaggga tgtgcgcttt atttctttga 1143481 cggagggcac attctgacat tatagcgaga tccataagct ccggaatttc aggcggagcg 1143541 ggtctcgttt tctatataaa agagaggtga aagcatttgc ggattttaca tacggctgac 1143601 tggcatcttg gaaaaacgct tgaaggaaga agcaggctga gtgaacaggc cgatgtgctg 1143661 gatgaactga atacgattgt aaaggatgag cagatcgatg ccattgtaat ggcgggggat 1143721 gcatttgaca ccgtaaaccc gccagcttta gccgagcagc tgttttatga aagcctgtct 1143781 gcgcttagcg acagaggaaa gcgcccgatc gtcgtcattg ccggaaatca cgataatcct 1143841 gaccgtttgt ccgccgcttc accgctgaca catgaaaacg gcattcattt aatcggttat 1143901 ccgacaacag agccgattca tattgaagtg ccttcagcag gagagctttt ggcggttgga 1143961 gcgctggcgt acccatctga agcgcggtta aatgaagtgc tatccgatac gtttgatgaa 1144021 aagctgctcc gtgatcacta tgatgtgaaa atcaggcagg cgtttgagca tatgacaagc 1144081 cggttccgga ccgatgcagt gaagattgcc gccagccata tttatgtggc aggcggaaac 1144141 caaaccgatt cagagcggcc gattgaagtc ggcggtgcat acacggtggc tgctgaaagc 1144201 ctgccggcag atgccgctta cgttgcgctc ggccatttgc atcgcccgca aacgatcaag 1144261 cgggcgcgga cgcttgcgcg ttattcagga tctccgctcg cctacagctt ttctgaagcg 1144321 ggctacgcta aatcagtgac gattgtggac gcaaagcctg gggaagaggc cacttggcaa 1144381 gaggtgttat tatcaagcgg caagccactt gtgaagtgga aagcggcaaa tggattaagt 1144441 gaggtgtaca gctggctgga tgaaggcaga gatcagaatg cttggattga cttggaaatc 1144501 cgtgtcgcgg accagctgtc acttgaagag attcacaggc tgcggaaggc gcacccgggc 1144561 tttatccata tcaggccggt ttttgaagaa cagaacaaag accgggaacg gatcgaggtt 1144621 aaacatgtct caatcgagga ccgctttaag aaattttatg aaaaacaaac tggcggtgcg 1144681 gtgccggatg aagaaatggt gaagctgttt ttagagcttg catcaggcgt tgaagaggag 1144741 gatgcgaaat gaagccgatc gccttaagca ttaaggggct ccacagcttt agagaggagc 1144801 agacgataga ttttgaaggc ctttccggtg ccggtgtttt cggcattttc ggcccgacag 1144861 gaagcggtaa atcctctata ctcgacgcaa tgacgcttgc tttatacgga aaggtggaac 1144921 gggcggcgaa taatacgcac ggaatcttaa atcacgccga agatacgctg tctgtgtcct 1144981 ttacctttgc gcttcagacg aatcaccaaa tctcatacaa agtcgagcgt gtgtttaaga 1145041 gaacggatga aatgaaggta aaaacggcac tttgccgctt catcgaaatc aaggacgagc 1145101 atacggtgct ggctgataaa gccagcgaag tgaataaaag agtggaggag ctcttagggc 1145161 tgacgatcga cgattttacg agagcggtgg tgctgcccca agggaaattt gctgaatttc 1145221 tgtctttaaa aggggcagag cgcaggcata tgcttcagcg tttatttaat ttggagcaat 1145281 atggagacag gcttgtgaaa aagctgagac ggcaggcgca ggaagccaat gcgagaaaaa 1145341 atgaaatgct tgctgaacag tccggtctcg gtgaggcgag ctcagaggca gtggagcagg 1145401 ctgaaaaggt tctcgaacaa gctgaagccc ggctggaagc gatgaggaag aaccgtgatc 1145461 aggcgaagga gcggtttaca gagcatcagg agatatggaa tgtccaaaag gaaaaatcca 1145521 cttatgaaga agaggaaaaa cgtctcgcag aagaacagcc gcatatagac agcatgcaaa 1145581 aacgcctgct ggaagcagaa acagcagcag cccttaagcc ctatgcggac cggtacgcag 1145641 aagcgatcca gcatgaggag caagctgaaa aggaacaaac gctagcccaa aaggatttag 1145701 cagaccggac agctttcttt cagcaaaaac atgaagagta tgaagcgtgg cgccagcata 1145761 aaagcgagaa agagcctgag cttttagcca aacaggaaca gctttcacgc ttgcaggaaa 1145821 tcgaaatcaa actgagtgag gccaagcaag aggaagagcg caaaaaggct gacctccggc 1145881 agaaagaaga ggctcttcaa tctgtcatga atgaattaga gaccgtaaca gaccgcctga 1145941 cacgagggca aaacagacag acagaattga agcagcagct caaatccctg caggtgacat 1146001 ccgatgagcg aaaaagctgc cagcaggccg cagagatggc attgcgcatc agacaaaccg 1146061 aggaacaaat caaaaaagag aaaaaacgaa gtgaagaatt gaacctcgtg ctgcagaaga 1146121 tgaatgaaga gaagaataca ctcgttcaaa agacggaagc ggaagaaaac aacatcattc 1146181 aggcatatga ggcagttcaa actgtgtacc atttggtgtg cgaaacggaa cgctcattaa 1146241 cacgtatgac ggaagaggct agaaagagtc aacacacgct tcacttacag cgtgaaaaag 1146301 caagggtggc actgctgaca aaagagttag cccaaaagct gactgccgga aagccttgcc 1146361 cggtatgcgg ttcaaccgat catgatccat ctgcctcggt acatgaaacg tatgaagccg 1146421 acagccatct tgaagaggac atcaaacgga cagatgtgtt attgacggaa gctgcagctc 1146481 tcagccagga gattctttca gccaaaatta tgcttgaaga acagtccgcg cgctttattg 1146541 aacagtgtcc gtttttgcag acaattcaag cacagaacct tgaagcggca gcttccttcg 1146601 aacatcagcc ggtgtatgaa gcatttgaaa ctgccaaatt tgaatggaaa cgaatcaagc 1146661 aggacattct ttctgttaag acacgaatgg cacaaatgat tggcgcctat caggagtctt 1146721 taaaaaaggc cgagcagctt aatgaaaaaa tcggttttga aaaaagagaa gccgaccgta 1146781 ttgaaagcat catcagtgag cttcaatcct caatggacag cagtctgaac atgtttaaag 1146841 aagcatttca gaatcaatct gtggacgaag cagaaaaatg gcagcaagcc attgaagaaa 1146901 aggaccgggc tgcagaagaa tgtgaaaaac gaattgagaa gagtatcgcg tttcttgctg 1146961 agcatgaagc acaaaaggaa aaactgcggg aatcgggaca ccggcttgag cgggaaaagc 1147021 tggagcttca ttatgcggct gaacgcatca agagcgtgat agctgattat gagcacgaac 1147081 tcggagatta tgcaaaagga gattcgattc aaatcaaact ccgctctgtc cagcaggatc 1147141 taaagctgtt aaaggaaaaa gaacaatctt tatatgaaga actgcaaagc gcccaaatga 1147201 agctcaacca agcgaaaagc cgcgcttctg caagcgagct cactcttcaa gaggcgaagg 1147261 gcagattgga aaaagcaaaa gctgcttggc ttgagcatac aaaaaacacc tccattaccc 1147321 ggactgagga ggttgaacaa agtctcatcc cagctgatga acttgaaaag atgaaaaccg 1147381 gcatagacca gtttatggat aaactgaagc aaaatgctgc aaacttaaaa cgagtagcag 1147441 agatacttgc cggcagagca ttatcagaga gcgaatggaa cgaaaccgtt gcagcattac 1147501 aagaagctga ggacgcattt ggcgctgcta tagaggaaaa aggcgcggcc gcaaaagcac 1147561 tggctgtcat tcgcgaccat cataaacggt ttaatgaaat tgaagctgaa ctgaaaaaat 1147621 ggcagatgca tatcgacagg ctggacaagc tgcaagctgt gtttaaaggc aataccttcg 1147681 tcgaattttt agctgaggag cagcttgaaa gcgttgcgag ggacgcctca gcaagactca 1147741 gtatgctgac aagacagcgc tatgccatcg aagtagattc tgagggcggc ttcgtgatgc 1147801 gggatgacgc gaatggaggc gtacgacgcc cggtttccag tttgtctgga ggagagacct 1147861 tcctcacctc gctttcactt gctcttgcgc tgtctgcgca gattcagctt cggggggaat 1147921 acccgctgca gttctttttc ttagatgaag gcttcggcac actggatcaa gatctgcttg 1147981 atacggttgt aacggccttg gaaaaacttc agtcagacaa cctggctgtc ggtgtcatca 1148041 gccatgtgca ggaactgcgt gcacggcttc cgaaaaagct gatcgtccat ccggctgaac 1148101 cgagcggccg cggtacgcgg gtatcacttg agttgatgta agggaggagc ggatatggca 1148161 aagcagattg ccggaatatg tgagctgtgc ggccggagcg atgtccagct gacagagcat 1148221 catcttacac cgaaagagga aggcggaacg tttttgccga cagcgatgct ctgtattcct 1148281 tgtcataaac agattcatgc cttatatacc aatcaagagc tcgctgtacg tttaaatgga 1148341 atggctgaac tcagaagcga tccagagctt gcccggtttg tcaaatggat cagaaaacag 1148401 ccgcctgaga agctgatcaa aactaagaaa tcaaatgaac gaaaaaagaa aaaatgacta 1148461 aaaagcagcc ctctctttgc agagcggctg cttttatccg tttccaacca tatcctgatc 1148521 gttgacatcg gggtctatat aatttgtcgc gttgactgca ttatttaata gaaggaaatc 1148581 tcccgtgttt cctgctcccg aaccgagcgc agattttgaa gagcttttcg gagaaaggta 1148641 aaaggaatca ccaaagttta cgactccgcc cgatatggaa ttgatagcta taggcccgac 1148701 aattgctggc ataaacgaca ccctttatcg aagtctctgt ttattatatg ttcttggcgg 1148761 gcgattgtga gcgcggagac tgaatctgtc tgatatgttt gagtctcgca tcaccgcgaa 1148821 taagcgaagc tgatccggca tgtaaaacag aagaggctga gaccccttga attttgatgc 1148881 tgcgaacata aatagccggc acctcgtggc aaaacgcgct ttgtacacct gtttcgggga 1148941 gcggcttcac ggcctgctgc tgaaagatct gatactcctt tttgttaaat gagccttcat 1149001 tatggtaaaa cgtggacaga gaacgctgca cagcaaatac ttttacactc atatcgattt 1149061 catttgtgtc gccaacttga aacacacttg cgatcccgag agaattaaac ttaactagtc 1149121 tgatgcgcga tatgcgttta agcattattc tggcgcaagc ggagcaaacg gcccaataat 1149181 aagagattca ggcggtgtat caaaaataga agacaggtag atggattcag tgtctccgat 1149241 gtggaaaacg gaggaactgg acacaccgtt catccgaata tccccgactt ccaagctgcg 1149301 gttgatgact gtaaagatca tgcttgctca tctcctttca tttctgatgg aatatgctcc 1149361 agaaagtgtt ctacagcgcg gatgacatca cgcttcacat gctcagcgat atgttctgca 1149421 tattgtgcag gcggtgtatt ttcttctttt ttgatatggg acatataata gtgaatcctg 1149481 ctgtccattt gttttctgat gtcttcaata acatgatgtc tgtttgtatc gtcaagtctg 1149541 ctgtcatatt gattttcaag ctgttccaaa atatctggga tttcctcggt taagtacatg 1149601 tcgacattct ggcggatctg ctgcatgagc tgagcgctct cttcctgctg catcatcccg 1149661 atttgcggtg tcgactggct gacgtcaaag ttttggacgc tgttcgggtc agtcggattt 1149721 aaaccgatat tcaaagtccc gtcgagcctt tcgattttca gctgatcaaa tttatactcc 1149781 acacgctcaa tggtagtggc cggccgctgt ttcatcgtat tcatttcagt ttgaatctct 1149841 ttcagctgac gttcgagctg ctgaatgtga atcgcctgct gctgaacgaa ggaattcaag 1149901 ttttgcaggt aagaggaaac agattgatca tacatgttct tcacctcttt catatgatta 1149961 acggccagga ggctggagcg ggaccaatga acctgtgtcg ggctcctgca gctggagcgg 1150021 ttgccctgag ccagaaactt ctggtgccgg ctctacatag cttcctgtat tatacaaatt 1150081 tgacagtgac ttgattgatc cggcgctccc gatttgcaga atggaggagt tgctgattga 1150141 ttccagccgg agatagttga tttgaatggt ttgattaata tagaagttca tgagcctcac 1150201 tccttttacg cattggccac gatcggctga tcaaccgcat cattgtcata cacattcgtc 1150261 gcgttttgat aattcatcac cttgaggctg tcgccggtat taaagctgcc agcaccggca 1150321 aacgttctga cctgagcctg aggagaaatc gtaatgcagt ccccgatgtg aacgactccg 1150381 ctcgtaccaa tcgcattaat tttaaacgct ccgacaatgg ccggcatacg agcacatcct 1150441 ttgttgaaaa attaaaaaaa gacaggtaaa gtgaaatgac aattccgatt tcaattgggc 1150501 tattcacgat agcttatgac aaacgcacat atgtgtgaga gaaattttaa ggggacatat 1150561 cggctctttg tgaaagcgtt ttattttttc gggccgttat gtttaaacat ggcaaaagag 1150621 gatgttgggt ataaattgag cggaaatgcg gcgaaggatg ccgctatccg cctatggtga 1150681 tttttgttta tttctttggt gtttttgcgt gtagaatgct ttttggagta tgtcgtgctg 1150741 cggtattcga tttttgggcg ggcacattct cgccctgagg tatatctcag aagtgctgag 1150801 caaaaatcgg agttaaatgt ggtgtattct aattgttata gaaaatgatt tacatacggg 1150861 agttttcaag atatctccca aaaatcattt cttctttaat ccgggtattc agcaggatat 1150921 ccagctcttg gctgcattga atcgtttctt ttgaattcat gccgtatttt tgtgcggttt 1150981 caattagtgt gatcctcatt tcttcaattt tactgttcat tacgctatct ccaattctag 1151041 attttatttt gatataaata caggatatcg ttagtataac ctattttggc tcaaaaggtt 1151101 gcctttcgtc aatttgacta aaaaagcgac aatttttgct gcggcctttt ttaatggaga 1151161 aaggactaaa gtcttgctaa gtgtgcttgc aaaaagtcct gccgttcctc aatttctcta 1151221 agtatgttgg tctgctcctt ttcgatttga aaggggcttt ttttgataaa aggatcatca 1151281 gcagcacttt gacaaatgtc aaggtgccat tcgttgatga gaggagataa tcgttcaata 1151341 gtaaacgacc gcttcagcac gtttttcatt aaggtgtgat attgcgacct gaaggcggga 1151401 atggatagaa gccttgacga aagcgtcttt ccttttgtca gaagcgggtc ttcttcatac 1151461 cattcttgta cggcaagcga tcttgtctcc atcggggaaa cgtaaagccg accggattcg 1151521 tttaaacaaa atgtgtagta aaagccttga ttggtgcagg tgttgccgat cagccacaaa 1151581 aaaaacagct tgacatccag atacaattta atcctttcag ccaattcgtc atctccggct 1151641 gtgcggatca gtatgaaaaa ttcatgtaag aatgccgagg aatcattgtt aaaaagggac 1151701 aatggaaccc ttggatcggc cgtcttcact ccgtaactcc ttttaccggc tggctgatgg 1151761 ttcttgatgt tcaaataaat gccttcaggc tggccattga tggtcagaaa gctgtacgag 1151821 gcaacgggag caggtacgcc gatctggtca aaaaaacaat aggcgagtct gcgccgcatc 1151881 agggacggat catcctgttc tgcattcaaa aaaagtgtcc tttcaccaag cagagacttt 1151941 tcccagctga tttcatagga tgccttttcc gctctgtcac gctgtgtgag aagaatggga 1152001 gaaacagatc gatctgttac gaaaagcccc ttggctgtac ctttcctttt cagctgctcc 1152061 cgatgaaaaa ataaatgcac gcgctccata ttctttcctc cttctcaaaa cgacatttgt 1152121 atgatatgta gagcaagccc gtcctgaaac gaaatgaaaa cggaattgag aaaaagggat 1152181 ttcagcattc gacagagaat acatgaagga gcattctgat ttaaaagatg atggaggaat 1152241 aacatgaaat ttgcgacagg ggaactttac aaccgaatgt ttgtcggcct gatcattgac 1152301 gatgagaaaa ttatggattt gcagaaggct gaaaaaaaac tgtttgaact tgagacgatt 1152361 ccgggatcgc tgattgaatg tatcgcagaa ggggataaat tcgttgcgca tgcaaggcag 1152421 ctggccgagt gggcaaagaa accgaatgat gagctgggat catttatgta ttcattatct 1152481 gaggtgaagc tccatgcacc cattccgaag ccatcaaaaa atatcatctg catcggcaaa 1152541 aactaccggg atcacgcgat tgaaatgggg agcgaggctg atattccgga gcatccgatg 1152601 gtatttacaa aatcgccggt aacggttacg gggcatggtg atatcgtaaa gagccatgaa 1152661 gaggttacct ctcagcttga ttatgaggga gaacttgctg tcgtgatcgg aaaaagcggg 1152721 actcgcattt caaaagaaga tgcatatgac catgttttcg gatatacgat tgtgaatgat 1152781 atcacggcgc gtgatctgca aaaaaggcat aagcagtttt ttatcggaaa aagcttggat 1152841 acgacatgtc cgatggggcc cgtgcttgta cataaatcat ctattcagga gccagagcgc 1152901 ctcaaggttg aaacaagagt caacggcgag ctgcgccaat ccggttcggc aagcgatatg 1152961 atcttttcca ttccggaatt aattgaaacc ctctcaaagg ggatgacgct tgaagcgggc 1153021 gacattattg ccaccggtac gccgtctggt gtcggcaagg ggtttacgcc tccaaaattc 1153081 ttgcggtcag gtgacaaaat tgatattaca attgatccga tcggaacgct gtcaaaccaa 1153141 attggctgaa taaaactgga gggcggaccc ggacccgccc gttttttctg ataatcatct 1153201 ttgtgacaga ggacaagttc atggtactat aagtggggta atttatctga tagggggaac 1153261 atatatgaca cacctacata ttacgacatg ggtggtagcg ctgattctgc ttttcgtcag 1153321 ctactcgctg tattcgtcag gaagtgcaaa gggcgcaaaa atcactcata tgattctgcg 1153381 gttattctat atccttatta ttttgacagg agctgagctg tttgtccgtt tcgccaactg 1153441 gaacggagaa tacgccggca aaatgattct gggcattatc accatcggcc tgatggaaat 1153501 gctcctcatc cgcaagaaaa aagaaaaatc aacaggaggc ctgtgggtcg gcttcgtcat 1153561 tgtccttttg ctgacagtgc tgctcggtct gcatttgcca attggttttc aattgtttta 1153621 atagaaaaac ctatgaaccc ggctctttga tagagctggt tttttttata tttatcccct 1153681 catattccaa atcatttaaa ataaccttaa aattccctgt aagcggtatc tcgtcctatg 1153741 aaattatgat accttcaagg agattcatta ttttgcagga gggataacat gaaacgcaga 1153801 aaattcagct cggttgtggc ggcagtgctt atttttgcac tgattttcag ccttttttct 1153861 ccgggaacca aagctgcagc ggccggcgcg atcgatcagg cggctgctct ggaaaacggc 1153921 aaagagcaga caggcgccat gaaggagccg gaacaggtga aatggtacaa agtgaccccg 1153981 ggagcaacgg atattcagaa aaactcacat atggcactga ccgtaaagag tgattcagta 1154041 ctgaatgtat ctgtatatcc aagtaaggaa aaagcgctta aagatgagac gtttgagatg 1154101 taccgttctt tcacagcgga ggatggaaaa agcgaagtca tttttccata cgcgtggagc 1154161 ggcccttact atgtaaaagt tgaatacctc ggagaagaag aaccagagga cggcggaacg 1154221 gcagaagcag ctgcagaagc caagtatacg attgggtata aaggcaccaa aaaacagccg 1154281 tcagatttag aagaggaaga agcttgtccg gttgaaatga gtgtcgatca gaagaaatca 1154341 ggaaaaggca tcctggataa gttgagatcg attcgtgatg agcagctgag ccaaacagca 1154401 gaaggcaaag aactgacaag cctttattac aaagcagcac cgtttatcgt tgcaaagctc 1154461 gcactcaata aaacagcaag aaatgaaatc tatcaggatc ttgtgacatt aaagccgtta 1154521 tttgacgatg tgtcagaaaa cggagcatca tcttcgtata aggtcactga aaaggatcaa 1154581 aaagcgatca accggctata tgataaagct ttacaatcag tcccgtcatt ccttaaagag 1154641 gagataaaga aacaagcgga ccgactaaat atgaagcagc tgcaaggcaa aacagcagga 1154701 gccattttaa cagaaaacaa tattgcagca aaaagtgaag ttcagacaac aaaggttatt 1154761 ttcaaggtga aggacaataa aagcctctca tccgtacata atgaaatgaa gggcttttct 1154821 gcaagcgcgc aatcgaaaaa agacatatct aatgtgaaaa aggcaaagaa actgtttgac 1154881 aatctgtatt catttgaact tccgaaagac gagaaacaga acggcgcata tacggcaagc 1154941 gccaaaaggg tcaaaagcgc tgctgcgaca ctatccaaga tgtccaatgt agagtttgcg 1155001 gaacccgtac aggaatacaa aagcttggca aacgatattc agtaccctta tcaatggccg 1155061 cttaaaaaca acggtgaaaa cggcggtgtc aaaaatgcgg atgtgaaata tgagcctgcc 1155121 aacacattgc tgtccaaacg caagcttaac gatacactca ttgcagtagt agacacaggc 1155181 gtagacagca cgcttgccga tttaaaagga aaagtaagaa cagatctcgg acacaatttt 1155241 gtcggacgaa ataacaatgc aatggatgat caggggcatg ggacgcatgt cgcaggcatt 1155301 attgcagccc aaagcgataa cggctattca atgactggat tgaatgccaa agcaaaaatc 1155361 atccctgtaa aagtgcttga ttccgcaggt tccggagata ctgaacaaat tgctctcggc 1155421 atcaaatatg ctgctgacaa aggagcaaag gtgattaatt taagtttagg cggaggctac 1155481 agccgcgtgc ttgaatttgc tttgaagtac gcagctgaca aaaatgtctt gattgccgca 1155541 gccagcggga atgatggaga aaatgcctta tcttatcctg catcttctaa atatgtgatg 1155601 tcagtcggcg caacgaatcg catggatatg accgctgatt tctctaacta tggaaaaggt 1155661 ctggacatct ctgctccagg gtctgatatc ccgagcttag tgccgaacgg aaatgtcacg 1155721 tacatgagcg gaacgtctat ggcgacgcca tatgctgccg ccgctgcggg actgctgttt 1155781 gctcaaaatc ctaagctaaa aagaacagaa gttgaggata tgttgaaaaa gacggcagat 1155841 gatatttcct ttgaaagtgt cgatggcgga gaagaagagt tgtatgacga ttatggcgat 1155901 ccgattgaaa ttccgaagac acctggtgta gactggcatt caggctacgg gcggctgaat 1155961 gtcatgaagg ctgtcagcgc agctgattta cagcttaagg tcaacaagct ggaaagcact 1156021 caaacagctg tcagaggaag cgcgaaggaa ggcaccctta tcgaggtgat gaacggcaaa 1156081 aagaaactcg gcagcgccaa agccggaaaa gacaatgcgt tcaaggtgaa tatcgcgact 1156141 caaaaacagg atcaagtact gtatctgaaa gcaacaaaag gcgatgcgaa aacatcgtat 1156201 aaagttgttg tcgtcaaagg aaaaccttcc ggcacaccga aagtaaacgc ggtgaaaacg 1156261 aaggatacgg cagtaaaagg gaaggcaaac agcaaagcga tgatcagagt gaaaaacaaa 1156321 tcaaagaaag tcattgcttc tgccaaagct gacgcaaaag gaacgttttc ggtgaaaatc 1156381 aaaaaacaaa aagccggaac ggtgctgtac gtcacggctg tggatacaga taaaaaagaa 1156441 agcaaggaag caaaagttgt tgttgaaaag taaccaaaaa gcggtgctcg atgcaccgct 1156501 tttttatttg cgcccccgtt ggactgctgt gtacataatg gatcgctttc cgtttgaagc 1156561 cgtccattca aaacggtctc ctgtcccttc gctgctgtag ttgtagtgat gctgcatcgc 1156621 gcattgtgcg gtgtcatttg aaaagtgata aaaggacaca ccctgccccg ccgaagtatt 1156681 cgaaaagact cctttattat aagaaaagac gcaatcgaat accgataagc cgaagctgtg 1156741 caagtgctgc agaaatgcga gaaaggtttc gtcgtcaagc gaatccaaaa gcgccatgag 1156801 cggccgcttg actgatttct catagcggat gcgttctccg ccggaaaggg agatgttttc 1156861 tgcaccgcat gccaaaacca acttgtcctg aaagccggct tgctcccact ttcctttatg 1156921 atggatccag attgggctgt gttggagact gtccgccagc agtatatcgc cttcaccgtt 1156981 ttcgattaag cagatgccgt cttcaatgag gatggtgccg tattcccact ttcgttcctc 1157041 tgtatataac aattgtttcc gtttcatcca tgctgtctcc tttttcttca ttcctctctt 1157101 ttctttccaa ttcaagcctg tcccatacaa ctcttttatg gacaaatcaa ctatctgcct 1157161 atagatgcat aaacttacta aggtgctgaa agaaacgaaa ttgttacgaa agaaacggga 1157221 ttggagctga tgtcacatgt gtggaattac gggttgggtc gattttaaaa agcagctcgt 1157281 ccaggaaaaa caaacgatgg acagaatgac agacactctt tccaaacgag ggcctgatga 1157341 ttcaaacgtt tggggggagc accatgtttt attcggacat aaaagacttg cggttgttga 1157401 tattgaaggc ggacgccagc cgatggcgtg tacctataaa ggcgatacgt acaccattat 1157461 ttacaatggc gagctttata acacggaaga tttgcgcaaa gaattgcggg cgcggggcca 1157521 tcaattcgag cgtacgtcag ataccgaggt gcttctgcac agctacatcg agtggcagga 1157581 agactgtgtc gaccatctca atggcatatt cgctttcgct gtgtgggatg aaaagcgtaa 1157641 tctgttgttt gccgcgagag accgtctcgg tgtaaagccg tttttttaca cgaaggaagg 1157701 ctcttcattt ctcttcgggt cggaaatcaa agcaatcctc gcgcaccctg atataaaagc 1157761 gcgagtggac agaacgggac tttctgaaat tttcggtctt ggaccgtcca gaaccccggg 1157821 cactggcata tttaaaggca taaaagaaat ccgcccggct cacgcgctga cattttccaa 1157881 agacggactt aatatttggc gttattggaa tgttgaaagc gaaaaacata cggacagttt 1157941 tgatgacacg gttgccaatg tcagatcgtt atttcaggac gcggtgacgc ggcagcttgt 1158001 gtcggatgtg cctgtttgca cattcctatc aggcggtctg gactcaagcg cgattacagc 1158061 gattgcggcg ggccattttg aaaaggaagg aaaagcaccg cttcatactt attcgattga 1158121 ttacgaagag aacgataaat attttcaagc aagcgctttt cagccgaatg atgacggacc 1158181 atggattgaa aaaatgacag aggctttcgg cacaacgcac cacaaatgcg tcatcagcca 1158241 aaaagacctc gttgatcatt tggaggaagc tgtactggtc aaagacttgc cgggaatggc 1158301 agatgtcgac tcatccctgc tgtggttttg ccgggaaatc aaaaaggact ttgtcgtcag 1158361 cctatcggga gaatgcgcgg atgagatttt cggcgggtac ccgtggttcc atacggcaga 1158421 tgttgagtct ggctttccat ggatgagatc aacggaggag cggatcaagc tgctttctga 1158481 ctcatggcag aaaaaattga atctgaaaga atacgtaaat gccaaatatg aagaaacctt 1158541 ggcagaaacg ccattattag acggagaaac gggtgtggat aaagcaagaa gacagctgtt 1158601 ctatttaaat atgctttggt ttatgacgaa ccttttggat cggaaggatc gcatgagcat 1158661 gggggcgagc ctggaagtgc gggtgccgtt cgccgatcac cggcttgtgg aatatgtttg 1158721 gaatattccg tgggaaatga aaatgcatga taatcgggaa aaaggcattt tgcgcaaagc 1158781 gcttgagggc attttgcctg atgacatttt gtatcgcaaa aaaagcccat atccgaaaac 1158841 acatcatccg gaatatacaa aaggcgtcag cgagtggctg aaaacgatca gaagccaaaa 1158901 ggactccgtg ctccatacct tactggacag aaaacaatta gatcagcttt tagaaacgga 1158961 aggctcctcc ttcaaggtcc cgtggttcgg gcagctcatg aaggggcctc agctgatcgc 1159021 ccatcttgct caaattcata catggtttga agcgtatcgc attgatattg acgagaggta 1159081 ggttcaatac aaatgtgatt aaaagccaga gatgtataga tttaaataag aaggatagat 1159141 gagcagggaa atatatgctc tatctatcct tttttgtaca acagcactat cgaattgccc 1159201 ccgcattcct tcaataagaa tgaataggtt ttaatgttct gccgataaaa ctagctgata 1159261 ccgggcttaa ctttaattcc ctagcccata cagaaagttg accaatatgg tgaatttcgt 1159321 gagcgatgat atggtgtaat atttcatctc gcgtatataa aacacctgtc tcccaaggaa 1159381 cgcttacaag ttcatctttt atttgatctg aatgtgtttg taaaacatca attatttcag 1159441 ttcggaatgt atttgagaga gatttcactt tattgagtgt ttgataatca gcgaactgaa 1159501 cagcgatatc ttcttttcct tggatagcac gaatccaact atattccaca tcaataatat 1159561 gaaaaagggt atataaaata ttctctactc cgccaagacg atttttaagt aattcttcag 1159621 tggttagttg atgacaccaa gtaaaccatt gatctctaac ctgccagtta tattcaaaaa 1159681 atttcatcac taaactcact ccaatactat catgtatcat aacaattagc ccttttttcc 1159741 gtgattcctc tattaatgaa gtgatgattg agaaatgttt acattctacc tgttgtatgg 1159801 cattaaaaat aataatgcat atctcgtcga tgatgctgtg cgtcttgtta cttttacaaa 1159861 gtaagaatcg gcattttctt catatacaat taggaaaaaa catactagac ttgaagaagc 1159921 agtgatacat aggagtgaga aaatgaaaga gataaaagaa gcttaccagc aatgcggaca 1159981 gattgttggc gaatacgcgc cagcctgttt caaagcatta tcatatctcc cgctaaagca 1160041 aagacaagcc tcttgggcag tattgtcgtt ttgccacacg gcggccagtg cagacgaaaa 1160101 ggtattgccc gcatttgaag ctaaagctga tcatgtttac caaaggacaa ataacggtaa 1160161 acaacatcta tggaaggctt ttgatcatgc gtatcggacc tttacattgg aaagcgaacc 1160221 ttttcgggag tttattgccg cacaaaaaga agacgccaag ccgtatgatg accttgatga 1160281 actgctcatg tacgcatatc ggacgggcgg tgctgccgga ttgatgctgc tgccgatact 1160341 gacacgccga aaacaagatc agctcaaaca agcagccgtc tctctcggct tggccataca 1160401 gctggttcgc ttcttaagtg atcttggcac agatcagcaa aaaaaccgca ttccccgtca 1160461 ggtaatgcag caattcggct atacagaggc tgatctccaa aaaggcaccg taaataaagc 1160521 gttcacaatg acgtgggagt atatcgcttt tgaagcagaa gcctaccttg aagagtgtca 1160581 ggatgccttg ccgctatttc cgcagtattc tcaaaaaacg gtgaaagccg ctcttcattt 1160641 gcaccgggct gttttagaaa aaatccgggc gaagcagcac gatgtatttc aatatcactt 1160701 cgctctcaca gagaccgaag tgaagcagat tctgtctgat atctaaaaaa cacccggcct 1160761 tgattgagcc gggtgttacg ccataccttt ttgaatccag atacgtgagc gccatcttct 1160821 gtacattaag attccccgga cccattcatc cgcgataaaa gaaatccaaa tgccggcaag 1160881 accgaaaccg aggtggatgc cgaaaagata agcaagcggg aggccaatgc cccacattga 1160941 aatcattgcc atgtaaaccg ggaatttcgc atcccccgcg gcccgcagag agttaatgat 1161001 aatgacatta aacgagcggc ctggttcaag gataatggtc atggcaatca ataggcttgc 1161061 agttgctata atgtcagggc tttgtgtgaa gagtccgatc aggtcttttg aaaagatcgt 1161121 catcaaaaca gaggtagccg cagcaattcc gagtgcccaa tataagctct tcatgcagcg 1161181 ctcataagcg gcatcaaatt gtttgccgcc gatataacgg ccgattaaga tttgtgtacc 1161241 ctggctgatc gcagtgccga acagcaaaat aaacatcgta atattttgcg tatacacttt 1161301 tgttgtcaac gcctgcgcgc ccatgatggc gataaaatac gtgactatca tttgcgacag 1161361 gttgtatgaa agctgctctc ccgcagaagg aatgccgatt ttcagcagct tgcgcaaatg 1161421 ctctttatgc atatgaaaga cttttttcag cgacatcttc agctggatgc gtttgttgac 1161481 aatcacaatc atcgcgatta atccgatgac gcgggcgata gatgtggaca tggccacacc 1161541 ggcaacaccg agaacaggaa agccgaacaa accgaaaatc acaacaaagt ttccggcaat 1161601 gtttaaaatg ttcatgccga tagtgacaaa cattgtatct tttgtgtagc cgtagctttt 1161661 taagatcgcg ctgaatgtca tgattaaagc ctgaataaag gacagacctc cgacaacttg 1161721 taaaaagact ttcgcatcag gcatcagtgc gtctgataat cccatcatat gaagcagagg 1161781 gacagccgcg aaaaagacga cggcgctgat ggccaggctg atgaagaagt tggcgccgat 1161841 tgacacataa gcgacttcca tggcttcttt cttttgccgt gagcctagaa attgtgaaat 1161901 gataacggtc gttcctgttg cgataaagct gaacatcacg ataattaaat ttaaaatctg 1161961 gttgctgacg ccgactgctg ccacgctgtt atccgagtat tggctgagca tcagtgtatc 1162021 ggcattaccc ataaacatat ataatgagac ctcaataaag atcggccaag taagcgaaaa 1162081 taatgagaac gttttgtcag cgggtttttt caaagcagtt gatttgaaga cagcttgttt 1162141 catcgtgtct aacccctttc gtaaataaaa tcaacgtttt aaagtgtacc tccatttcct 1162201 tataataaaa agggatagaa acgatacttc ttgtaaaaat ccgacttaaa aaggaggatg 1162261 attcaaatgc ctcgcatcct gtttacagtc ccgccttttc cggtatttat cgcagctggg 1162321 gaaggggttt ttaaaaaagg agaaacccat gtgaaacgtg tattctccgt gtttgatctg 1162381 atatatgtca aacagggaac gttatatata acggaaaatg aaacatcgtt ttctgttgaa 1162441 ggcggcgagt acatcttgct ttctcccggt cttgaacact acgggacgaa gggcagtgat 1162501 gaagcaacct cctactattg gcttcacttc gatgaacatc gatatgaatt tacggcaaag 1162561 ggaggcagca actggtctga gcttcagcag gaaaaaggga gcttcgaaga gctggcccgc 1162621 tacggattgg ccttgccgag aaaaggcaag gtgcagcgcc cgcagtttat ggcgcagcag 1162681 tttgaaaagc tgatcgatta ctccgcggaa aactctgatt tgccgctcag aaagcaaatt 1162741 ttatttgagg agctgatgct gcatcttcaa aaagaagcgt tccaaatacc gtctgcgaaa 1162801 gagcgggtag cctgggaggc ggcccggtat ttacaggagc actataagga aaagacgaca 1162861 atcaaggatc tgtcgctcgc ccttcactat catcaggatt atgtgagccg ctgcatgcag 1162921 caggtgctcg gcgtaactcc ggcacaatac acgaaccggg tgagaatgac ggaagcgaag 1162981 cgtcttttat cctctacaaa tgataaaatg ggcgttattg cggaaacggt cggaatggaa 1163041 gatccgacat acttttcaaa actctttaag cagatagaag gcatttcacc aattgaatac 1163101 cggaaaattg tcagccggaa agttcaataa ccagacgagg gatgaacatg aaaacaacaa 1163161 tttacgatgt ggcaaaggcg gcgggtgttt cgatcacaac tgtgtcccgt gtgataaaca 1163221 atacggggag aatcagcgat aaaacacggc agaaggtcat gaatgtcatg aatgaaatgg 1163281 catacacgcc caatgtccac gccgcggcgt taacgggaaa acgaacgaat atgatcgctc 1163341 tcgtggcgcc tgatatttca aatccgtttt acggcgaact ggccaaaagc attgaggaaa 1163401 gagcggatga gctcggtttt caaatgttga tttgcagcac cgattacgat ccgaaaaaag 1163461 aaacaaagta tttttctgtg ctgaaacaga aaaaggtgga tggcattatt tttgcaacag 1163521 ggattgaaag ccatgacagt atgtctgctt tggaggaaat cgccagtgaa caaattccga 1163581 ttgccatgat ttctcaggat aagccgcttc ttccgatgga tattgttgtg atagacgacg 1163641 ttcgtggcgg atatgaggct gccaagcatc ttctgtcact cggccacacg aacatcgcct 1163701 gcattatcgg agacgggtca acgacaggcg aaaaaaatag aatcaaaggc ttccgtcagg 1163761 cgatggagga agcgggcgtg cccattgatg aatcacttat catccagacg cggttttcct 1163821 tggaaagcgg caaggaagaa gcgggaaaat tgctcgacag aaatgctccg actgctattt 1163881 ttgccttcaa cgacgtattg gcttgtgccg ccatacaagc tgcgagaata agaggcataa 1163941 aagtgccgga tgatctttct atcattggtt ttgataatac gatactcgca gaaatggcgg 1164001 ctccgcccct gacaaccgta gcccagccga taaaagagat ggggcggagc gtcatcgaac 1164061 tgctggcaga agcaatagag ggaaaacgaa aggcgaaaca aaaaatagtg ctcccgcctg 1164121 agcttgtagt cagacattct acatcaccgc tcaacacatg agcccgctaa tgagcgggtt 1164181 ttttcattat gacagttgaa gccaaaaaaa catattgcgt gtaaaccaaa ggcggtgtaa 1164241 aatataacca tcttttgaga aagcgcttgc gcaaaatggc agagcggata gaaccgctgt 1164301 ttttttagct gttaagagaa aacgctttct caaagcgagc ccgaaatgag ataaaggaga 1164361 ggatgggacg tggaacatca agtaagatgt gcagtattgg gattaggaag gctcggttat 1164421 tatcatgcga aaaatctcgt caccagtgtg ccgggggcaa agctggtttg tgtcggtgat 1164481 ccgttaaaag ggagagcgga gcaggttgcc agagaactcg gtatcgaaaa atggtcagag 1164541 gacccgtatg aagtgttaga agatcccggc attgatgctg tcattatcgt aacgccgaca 1164601 agcacacatg gtgatatgat catcaaagca gccgagaacg gcaaacagat ctttgttgaa 1164661 aaaccgctga cattaagcct tgaggaatca aaagcagctt ctgaaaaagt taaggagaca 1164721 ggtgtcatct gccaagtcgg ctttatgaga cggttcgatc ccgcatacgc agatgccaaa 1164781 cggcggatcg acgctggaga aatcggcaaa cctatctatt ataaaggctt tacgcgcgac 1164841 caaggcgcgc ctcccgcaga atttatcaaa cacagcggtg gaatttttat cgactgttcc 1164901 atccatgact atgatattgc ccgttatttg ctaggggcgg aaatcacttc tgtttcagga 1164961 cacggcagga ttctgaacaa tccgtttatg gagcagtatg gcgatgtgga tcaggcgctg 1165021 acgtatattg aatttgactc gggcgcagcg ggggacgtcg aggcaagcag aacctctcca 1165081 tacggacatg acatccgggc ggaggtgatc gggacagagg gcagtatttt catagggaca 1165141 ttgagacatc aacatgtgac catcctatcg gctaaaggga gcagttttga tatcattcca 1165201 gactttcaaa ctcgttttca tgaagcctac tgcttggagc ttcagcattt cgccgagtgt 1165261 gtccggaatg gaaaaacacc gattgtgact gatattgatg cgacgatcaa tttagaagtg 1165321 ggtatcgccg caaccaattc ctttcgaaac ggcatgccgg tacagctaga tgtgaagcgc 1165381 gcttatacag gtatgtaaaa gctaagtatg ttgcatttga ggctttccgc aaaaaaagca 1165441 agggcatttt agcccttgct ttctcttttc tcatataaat agtacatata atcagtaggt 1165501 acgcctgaat ggtccagctg tctcagcatg gcggttacgt tccctctgtg gtaagtgccg 1165561 tgattgacga catgcaggat ggtgtctgca taggttgatt ccagtgtacc tagtttcgga 1165621 tgctgcattg tgaaggtctg ttctaagtcc gtctggcggc tgaagaaatc atgatactgt 1165681 gactccagct cggcagcgtg ctgtttaatc gctgccatat taccttgcgc ggactgtaat 1165741 ttgcctgcgc tgtctataat ctcttggtag gccactcccg aaagaacatt cagccaaatg 1165801 tagtcagccc tgcacatatg aagcagcacg tcgctgacag aaggaaatac gctctttact 1165861 tcttgatagg cagtttcctc cggcaggttt tcgatatggg taaatatttt cttgtttgcc 1165921 caagaatgat agtcataaaa ctgttttgca tcagtcatca gcatgccccc ttttctaaga 1165981 aattcgtttt tttcatctgt ttctccttca attgcaaaag agtgacaccc caaaatatcc 1166041 tgccgctgcc cacattaccg ctgcagagca tttgtttacg atcagcataa gcctgccgct 1166101 cgtatctatc gtctgaaaca accggcccgc tattgcaagg ctgatgaacc aaatccaaga 1166161 cacagcgatg caggcggcca taaagagcca tttctcaagc cccgaatatt gaagagagct 1166221 cgtgccgatg acgccgatcg tgtccagaat ggcatgcggg tttaaaagag aaacagcggc 1166281 cgcaaacgca gcttgctttt ttggtgtgaa cgtatgtttc tcattttggc ttgtgttcgg 1166341 acggatgttc caagtcaccc agcccatata aagcaaaaat aaaaatccgc cggccatcat 1166401 gactgtctca aacacaggca gctcctgcac aatgacagac acgcccgcaa cggctaatac 1166461 aattaacaag gtatcgcaga ctgaagcact gatgacagct gggagagccc gccaaatatg 1166521 cttttgcaac gcgccttgct gaaaaataaa cacattctgc actcccagcg gcaaaattaa 1166581 gccaaacgcg agcacaattc cgtgaatgat tgcattcatg ctgaaaaagc tcctttcaca 1166641 ttttttttca atcataagag agattgtcac taaagtctcc agccatttgg ttgggttagg 1166701 aaccagccaa atgtataatg tgtaaaaaag gggggcatga ccttgtcgca atggcagcca 1166761 agccgaaagt cggatgttcc gctgcatcgg cagatcgaac aatatatgaa agacaagatt 1166821 cttcacggag agtgggctgt agggacgaaa atcccctcac agagaacgct ggccgacatg 1166881 tttcaagtca accgcagcac agtcacagca gccatagatg aactcacgtc tcaaggcttg 1166941 ttagagggaa gaaaaggcgg cggtacgaag gttgtaaaca gtacttggag cgtgctgacg 1167001 gctgagcctc cgcttgattg gagcgattac gtccgttcgg gcattcatcg cgccaattct 1167061 tccatcattc aagctattaa tcagaacgaa ccaagagcgg atatcatcag attaggaact 1167121 ggagaacttt caccggatct tgtgcctgct gacacaattg gacggatgtt tcagcaaatc 1167181 aatccgggcg tcctgtcttt aggatatgag cagccgaaag gaaaccgtca gctgcgggag 1167241 gcagtggccg accatttaaa aggaaagaag atccatgtgt caccgtctgc aattttaatt 1167301 gtgtccggtg cacttcaggc acttcagctc atctcaattg gacttttaaa acgagattct 1167361 gtcattttga cggagaagcc gtcctacctt caatccttgc atgtatttca atcagctggg 1167421 atgcggcttc gcggcttgcc gatggatgat gaaggggtca aagcggggct tgtttcttct 1167481 aatcgaaaac aatatggagg acagctgctt tacacgattc cgtcgtttca taatccgaca 1167541 ggcacagtca tgtcagagca gcgaaggaaa gagatcatca gcctgtcaaa aaaagagcag 1167601 atgcccatca ttgaggatga tgcgtacggt gatttatggt ttgaagaaaa accgccgcag 1167661 ccgttgaaag caatggatca tgagggcaat attctgtatc tgggcgcgtt ttcaaaaacg 1167721 gttagccccg gtctgcgaat cggctggctt gccggtccgg agccggttat tgaaaggctg 1167781 gcggacatta aaatgcagac agactacgga tcaagcggcc tgtcccagtg ggcggctgcc 1167841 gagtggctgt cacagggata ttatgaagag catctgactt gggtacgcag gaagcttaaa 1167901 gaaaggagag acgccgccgt tcattttctc gagcggtatg ccggggacat tgccacgtgg 1167961 cggattcccg caggcggctt ttatatttgg gtgacatttc acaaaaacct gcctgtcagc 1168021 cgtttctttt atgaattgct gaaacggcag gtgcttgtga atcccggcta tatttatgac 1168081 ggtgaagacc gaaacagcat caggctgtca tattcctatg catctcttgg agatttggaa 1168141 actggcatta aagcggcagc tgaaacagca cgccgcctga tgatgtccta ggctttggtt 1168201 atacgatgac agctcccagt gccctggcga aggcaatcgc gtgctcaggt gcgattttgc 1168261 agcctttcaa tttgtcgagg gagacatgaa gctgttcaaa acggcacgtg ctgatgtcca 1168321 tgttttgaag ggacgtgccg gtaaagctgg cgccttccaa ttcgcatccg tcaaagtgtg 1168381 tctgctggag caccgtatcg ctgcattcac tttgcataag agcacagtga tcaaatcgaa 1168441 cttgtttcat atttgagtac gaaaatgagc tgaaatgtcc gtggcattcc tcgaatgaaa 1168501 cattccgcag cgttgcttcc gccacattca ttccaaccat ttttgactgc ttaactgaag 1168561 ttctgtgaat gacagccccg ctgaaatcgg cgtttgataa atcgcatttt tcaaagatca 1168621 catcggtcag ttcaatatgc cgaaaagaca catcgataaa gacgacattt ctgaataccg 1168681 ttttttcaac acatagtctt tcgatatctt cgccgcagat ggtgcaatct tcaaacaaat 1168741 gcatgctgat tacatcatcc tgtgtcacgg catcatgaaa atctgcggtt tgcaggtttt 1168801 ccggtatgtt cggtttttga attgcgattt tattcatgtg atgacatcct ttgctgcccg 1168861 aaaaacagag gcttccgggt tcaatttaat agatcgttaa ggaaattgat acatatagta 1168921 aatcgtgaag agccttttct tggtacagca gcccgcttgt tttgtaagca taaatggaaa 1168981 gcttcctata cgtcaaggcg tttacaggcc gaaaaagcca aagggaacag gaggaatgcg 1169041 gaatggggca ttacatcaaa accgaggagc atgtgacact gtttgtagag gatatcggac 1169101 atggaaggcc gatcatcttt ttgcacgggt ggccgttgaa tcataagatg tttgaatatc 1169161 aaatgaatga gcttccgaaa aggggatttc gttttatcgg cgttgatttg cggggatatg 1169221 ggcaatctga ccgcccttgg gaaggctacg attatgacac gatggccgat gatgtgaaag 1169281 cagtcattta tacgctgcag cttgagaatg cgattcttgc cggtttttca atgggcggcg 1169341 caattgcaat ccgttatatg gcaaggcatg aaggagccga tgttgataag ctgattttac 1169401 tgtctgcggc ggcccccgcg tttacaaaac gcccgggtta tccgtacggg atgaggaagc 1169461 aggatattga cgatatgatt gaattgttca aagctgatcg gcccaaaaca ctggctgatt 1169521 tagggaaaca gttttttgag aaaaaagtgt ctccagagct taggcagtgg tttctcaatc 1169581 tgatgctgga ggcttcctcc tacgggacga tccactcggg catcgcatta agagacgaag 1169641 atctcagaaa ggaacttgct gcaatcaagg tgccgacgct gatcctgcac gggagaaagg 1169701 atagaattgc gccgtttgat tttgcgaaag aattgaagcg cggcatcaaa cagtcggaat 1169761 tggttccgtt tgcaaacagc gggcacggag cattttatga ggaaaaagag aagatcaaca 1169821 gtttgattgc gcagttctcc aactcataag aaaaaacccg acattgatcg ggttttttat 1169881 ataattcctc tgttttgcag tgcgttaatg atgagatcag ctccatcgga aatagaggtc 1169941 tggtcagact caatgatgaa atcgggtgaa agcggcgctt catacggaga atcgatcccg 1170001 gtgaaatgtt tgatctctcc gtttcgcgct tttttataaa gcccttttgg atcgcgctgt 1170061 tcacaaacat gcagcgggca cttcacataa atttcgaaga actcaccttt aggaaagagc 1170121 gctctaacca tgtcccgatc ctctctgaat ggagaaataa aagccgttaa aatcatttgc 1170181 ccgctgtcga caaacagctt cgccacttct ccgatccggc ggatgttttc aatcctgtca 1170241 ccagtctgaa atccaagatc tttgtttaag ccgtggcgga tattatcacc gtcaagcacg 1170301 tagctctgaa tgcccttgcg gtaaagcttt tcatcgacag cattggccag caccgatttt 1170361 ccggagccgg acaaacctgt aaaccaaagg acgcagcttt tgtgtccgtt taaggactgt 1170421 ctgtcagact ttgagatggc agcgggatgc caaatgatgt tcggattgtg tgtcattgca 1170481 attccccgct gttttgcttg atggcaacag gctgttggtg aagtcccttg atcagcacgg 1170541 ctgcgacctc aggccggctg aattctttag gcggcttttt gccttggcgg agaagctctc 1170601 tcacttttgt gcctgataag tggatgtggt ctctcgggct gtgcggacat gttttggagg 1170661 tgcccatgtt tccgcatttt cggcaataaa agctgtgctc aaaaaacagc ggcttgatgc 1170721 ccagctcttc ctctgtgaat gattgaaaaa tattttgggc gtcgtatgtt ccatagtagc 1170781 tgccgacacc cgcgtgatca cggcctacaa taaaatgggt acagccgtaa ttttttcgga 1170841 cgagcgcatg gaaaatcgct tcccgcggac ctgcataacg catggcggca gggaaaaccg 1170901 ataacatgac acgatccttt ggataatagt gattaagcaa agcctggtag ctctccattc 1170961 tgatatcgct ggggatatcg tctgactttg tttctccgac aagtgggtga agcagcagac 1171021 cgtcgaccgt ttctaacgct gttttttgaa tgtattcatg cgctctgtga acagggttcc 1171081 tggtttgaaa gccgacaatc gtcttccagc cgagtttttg aaaggccgct cttgtttcag 1171141 cgggcgttgc ataaaactgt tcgaaagatt tgtcaggcag gctgctgacc gtgataggcc 1171201 ctccgatata gtaatccggg cgcgccagca atttttttac gcctgggtgg gcaggatcgt 1171261 ttgttttaaa aacagacagt gcttcttgtg ttttatcagg ctggtatata tcggtgactg 1171321 tgatcatgcc gtaggtaaca ccgtctttca caagcttgac gtgatctccg gcagacagct 1171381 gtcttgctgt tttttctccg acaggcagcg taatcggcag gctccacggc aagccgtttg 1171441 ccagcctcat ctctttcaca acggaatgat aatctttttc tcccaaaaaa cctgttaacg 1171501 ggctgtagcc gccgatcgca ataagctcca gatcactcag tgcaagctga tccagctctg 1171561 cttggcacgc gcacccttca aaatggcatg cgggatcaca gcggttgatt aatacccctc 1171621 cgtggggttc gtttccattc aacgtgttca acctccattt atacgtttcc ttgttttctt 1171681 ttctgcactt aatgaaagtt tgacatcagc gccttaacat catttcgatt ctcacatcaa 1171741 gaacctgcca tccgctattc ttgatgcagg ccgcattctg ttttctcccg tccggcccat 1171801 cttccagccc tctcatcgtt cgggtccggg gaaggcagtg tacacatttc acagcctatg 1171861 ctcggataat gttgatcgtg cagtttgtta taaggcaaat tgtgcaggcg gatgtacgtc 1171921 caaacgtcat cccatgtcca gtggataagc gggcaaattt tgatgagctc aaacttctgg 1171981 tccaggttta cgtattgaat atgctttctc gttggtgact gatcccggcg cagtcctgaa 1172041 atccaagctg tcatgccgga caggtgcttt ttgagcggtt cgattttccg caattggcag 1172101 cagaggttcg ggttatgctt ccacagctct ccgccgtact tcgtcccctg ttctgttaag 1172161 ctcagctcgg gttcgagcat ctggattgca aatcccggat atcgttcttt gacggtctcg 1172221 atcagctcat atgtttcctg aaaatgaagc ccggtatcca aaaagatgat gtgtgcgttt 1172281 ttgttgattt ttgatattaa gtcgagaagc accattcctt ctgcgccaaa gctgcaggcg 1172341 tacacaatct tttctccgta cgttcggtaa gcccatttca acacatcgag ctcatcgatc 1172401 aattgatccg ttatctgttt ggacagcatg tcgttccaag tgtcatatgt gatggtttcg 1172461 ttcaatgttt tccccccgtt tgcatctgct ttttttatct attgatcgag ttataggcag 1172521 actattcatt ttttgcataa aggttcaggt tttaggtgcc gcgcccgcct aaaatgaggt 1172581 gcggaaccat taagagcccg gctgaatatg ctttttagca aaatggtttt atgcccaagg 1172641 agaggtagta tgccgattgc catttatcag gggcatcatc attcgcttgc cccggcggac 1172701 attaacatcg tcattgatgt catcagagcc tttacggtcg cccattatgc gtttatcggc 1172761 ggggcgaaag agattttgtt ggtccggaca gctgatgaag cctttgcgct gaaagacacc 1172821 tatccggatt atgttttgac gggagaggaa aagggggtcg gtatcagcgg atttgattta 1172881 gataattctc caaaacgtat ggctgggcag aatatgacgg ataaaagcct gatccagaaa 1172941 acaacaaacg gcgtcacagc agcattgggg gcgctgaacg caaagcatct gttcgtaact 1173001 ggattttcca atgccaaaac aacggcacag catgtgaaaa agctcgtcgc aaacgattgt 1173061 gtcataaaca tagtggcttc ccatccatcc ggtgatgacg atatggcatg tgcggagtat 1173121 atcaaaggca tcattgaagg gacaaatgtg gtaacggctg cggaggcgat tgaaagaata 1173181 aaaggctctt ctgttgcgga gaagtttttt gactgccgcc agccattgtt tgattcggaa 1173241 gacatcgttt actgtacaaa agaactgacg ggcgatttcg tgatgaaagt gaaacaagat 1173301 ggagaagttc caacgataga gagggtcata atatgaatga tttttcacta gaattgccag 1173361 tgagaacaaa caagccgaga gaaaccgggc agtccatttt aattgataac ggctatccct 1173421 tgcaattttt caaagatgcg atagccggag cgtccgacta tattgatttt gtgaaattcg 1173481 gctggggcac atcattactt acgaaagatc ttgaagaaaa aatcagcaca ctgaaagaac 1173541 atgacattac atttttcttt ggcggcacac tgtttgaaaa gtacgtaagc cagaaaaaag 1173601 tgaatgaatt tcatcggtac tgcacctatt tcggctgtga atatattgag atttcaaacg 1173661 gtacgctccc gatgacaaat aaagagaaag cggcttacat tgccgatttt tctgatgaat 1173721 ttcttgtgct cagtgaggtg ggcagcaagg atgcggaatt agcaagccgg caaagctctg 1173781 aggaatggct tgaatatatc gttgaggata tggaagcggg cgcggaaaaa gtgattacag 1173841 aagccagaga aagcggaacg ggagggatct gttccagcag cggcgatgtc aggtttcaaa 1173901 ttgttgacga catcatttcc tcggatattg atatcaacag gctgattttt gaagcgccta 1173961 acaaaacgct tcagcaaggg tttattcaaa aaatcgggcc gaatgtgaat cttgccaata 1174021 ttccatttca tgatgccatc gcgttggaaa cgctgcgttt agggctaaga tccgatacct 1174081 tttttctgta aaatagcggc tgcggggctc tcgtcgtgaa gagagcctct gcctattatt 1174141 ttttatggcg gtacataggc gtgagatagg gaagtgaggt caggcggatg ttgtagatga 1174201 agtcgatgac tcttgtcgat atcacctggc atatgagggc ttgaatgacg atgccccagt 1174261 caataataga cgcggtgacc ataaaaatga tgcaattcat gatgagcagg atcgttccag 1174321 gattcccgcc gcggtagata gaaatcatca gagcaagggc tccgaatcct ccgttcgaaa 1174381 ttttatattt gtataaaagt ccgattccga gtcccaataa cactgcgccg cttgccagat 1174441 caagccacag gttagatgtg atatcaggaa aaactgcatc aaagatcaat accgagacag 1174501 aggtgacggt gatagaagcg agggtgccgg tgaatgttct catctccagc cattttaaag 1174561 cggtaaaaag cattgataca ttcacagccc acactgaaaa tccgtggggg atttgaaaca 1174621 gataatgcaa tagcaccgca atacctgctg caccgcctgt cggaatatca tgcggaaata 1174681 aaaacaagga catgccgagt ccttgtagta cgccgcctac gacaatcata aacgtaagtt 1174741 ttgctttcat cagcagttca gccattaagt catttgctcc tttatgaaaa gacttgtccg 1174801 ctgttttcat tttatgaggc tgtccattat ttatgtctca aaataaagaa atggcccagc 1174861 ttaataggct gagccatccc acttgtagcg attgacgatc tccatattga tctctgtgcc 1174921 aatgcctttt cctttcggga tgtggaccat tccttttgaa ggctgcaggc tgacgagatc 1174981 tgtaaaagga ttctccatga cgtcccactc gatcggttca atgtgatcgt tcttcatttt 1175041 agaccatggg ggcagacagg cttgtgcaaa taaagcatag agccgtgaga gcgatccgtc 1175101 atatgcatgg gcggatgctc tgacgccgaa ataacgcgcg agctggaggc agtcccgaaa 1175161 ctcatcaatt ccgttgacat gcatgacatc gggctgaatg atatccaaac agcgctgtga 1175221 aaggagaggc acatattgcg ccgggccttt catgttttct ccgccggcaa caggaacaga 1175281 caaacggctt cgaagcatag cgtaatcctg cggctgatca aagggcaaag gctcctcaag 1175341 ccagccaatg ttcgtccatt cggagaaata gcgctcccat ttaaaagccg cagcggcatc 1175401 gtagctttgg tttgcgtcca gaatcatcgt aatggagctg cctgctgtat gctgcagcgc 1175461 attgatgtgc cggacatcct ccttgaatga agtcccgcca attttgactt tgatttgctc 1175521 aaaacctttt ttcaactggg cttcaacatt ggagactgag cggctgatcc attgcgggga 1175581 gtctgagtac gattgaaaag acgcgtacac aggaatctcc tctctgtatc gcccgcccca 1175641 taattcgcaa accgaacaat ccgcagcttt ggctgcaatc tctgtcagcg ccatgcttac 1175701 agcggaggcc gcccgctggt gccatttttg aatcgtgcgc actaatgaca ggcggctgcc 1175761 agcctgtttt cctaatagaa atgggatgat ccgcttcgta aaaccgacat ggagagcagg 1175821 gagccaatca acgcattctc cccagccgtc tatcccgctt tcggtgataa tcctgatgag 1175881 ataacaagtc cgatatcgtt taaacccatt ggcatctccg tatggctttt ctaatcgatg 1175941 aaatagcgga aaggtttcaa tccgtacaat tttcacactg ggtgctacct ttcctcagcg 1176001 ggctggagcc gattgccagc cattttaggg tcttcttttt cttttgtttc ttcattgttt 1176061 tgcttcacat ggatgagcat catcacaaga atcccgacaa cgagagtcaa tcccgcgatg 1176121 cttaaaaaca tgccgggtct ggaccattgc atcaggcggc cgaaaatcgg aggaccgatc 1176181 gctaccccta agaaacgtac agagccgtac agcgaggtga caaatccccg tctttctttg 1176241 ccgacagccc cggtaatgaa actgttcaca caaggaagga caagacctga gcctatactg 1176301 ctcagtacaa gaacactgat aaaaaggaca agattttcaa tgaatgacag tgccgcgtag 1176361 gatacggtca tgaacgccaa tccaagtacg atcagctttt tcattaacga ttgcttttgc 1176421 ccgattttgc ttcctgttgt ataggacgtc acacacataa ccaaaagcgg gatcgctaaa 1176481 attaagcctt ttttcacgcc gtcggtgtcg tatgtttttt caagaacatc tgagagataa 1176541 aacaggatgc cgaataaagt aaacaaacag gtcgcaccgg ctaaataagc ggtaaacagc 1176601 catctgcctt catgtttaaa gacacttaac agcccttttg catattgtcc gattggtggc 1176661 ggttcttttt cctttttctt ttctttaata aaaatccaag tcagtacgat cgaaatgata 1176721 caaaacacag gaaaggcaaa aaacgcgcca taccagacaa gcagggcgat cagcgagcca 1176781 atgatcggcg atagcacttt ccccatgccg tttgaagctt caacaaggcc gagcaccttg 1176841 ctctcctggg cgcctttaaa cagatctccc gtcagtgcca tggcaattgg gccggttccg 1176901 gctgccccga ttccctgtaa cgctcgtcct gccatgaccc aaggataggc attgtcaaaa 1176961 aaacctgccg caaacccggc taacaaaccg ccggcaccat acaaaattaa gcagggaata 1177021 atgatgactt tccttgagaa tcggtctgcg agataaccga caatcggaat cgcaaatgct 1177081 gcaatcaagg aaaatactgt gatcacgaga ctgacttgaa attgtgataa atgaagttca 1177141 gatttcattt ttggcaaaat cggaataagc atcgagtttc ctagggttaa tattaaaggg 1177201 attgaaccga ttgccacaat cgtcattccg ttattttgtt ttgatgattc catctcagag 1177261 cacactcctt ttcttctgct tagaatgtcc ctgatggctt cgtttattca gcgatcagac 1177321 agcaaaaaac cgaacagaag atacctgttc gggaaaaaag agggttaacc gagagcctgt 1177381 gaaatcaaag catataagtg tccattttga ataggcgctt ttttctgata gaacaaaatc 1177441 ggaggttcat catctttatg aaatcccatt tctatcaggc tgtcatgcag agacgtgtgt 1177501 tcactcggta tatcgattcg catcggccct tgtttgccgg ccgccagcct tgtaattatc 1177561 tgtgctgcaa catctgatga tggagcgatg atagggccga atttcaaatt ggccggtgtc 1177621 tgtacagaaa gtccgtagcc aatgagctgt ccgtcctgat ttctggcgat gatacattcg 1177681 catgaagcag aaataagctg ctgcaaaagg tttgatcgat ctccgccaaa ggcagccaga 1177741 tccgccgcgg ttaagtcgtg aaagtcttgt tctctaaagg atgtcagttc agcatcaagc 1177801 ttttttgtat aaggttgaaa actgtgacag ctgtactttc gcactgaacc tgccgtatga 1177861 aaacctgctt tttcataaag cggcaaacct tcttttgtgg cgcaaagcct gatggcggtg 1177921 ttttcatccg tttgggtaat acaggcgttt accatacgcc ggccaagacc gagccgttga 1177981 tattccttgt caacgataac aaggccgata gaagtaagac ggccaaacaa aaacaagccg 1178041 atgcaggaaa taatatcacc gctgacattt tgataaccga aaaagcgtcc ctgctgaaca 1178101 agcagtttca gctcttgttc gccataatcc ggccacccgg cttgcccgca aagccgcaat 1178161 aagccggaaa cgtgttcttc atgaagctta atcagttcat ctactacgtc cataagatca 1178221 cctgcttgtt ctaagtgttt tgtacatgac aatatgattg ccaatgccgg gaatgtcaaa 1178281 tggttcgcca agttccttcc agccaagctt ggcatagtag cccttgacat ggtgtcttgc 1178341 gttgcaccat accgcctgaa cgccgctctc cgccagtttg tgctccgcgt gtttgatcag 1178401 cgtgcttcca gctttttgat cgcgatatcc ctcgagcgtt gccatgcctc tcagccgata 1178461 cgcagaggct tccgttaata aaggctgact ttgcggggaa aaagaagcga tgctgatcag 1178521 cgttccatca taaaacacgc cgagatgaaa ggagccttct gcgtgatcct ctttatattt 1178581 gcattgttcg atggattgat ggggacgcag aatgcgatgc cggatttcat atgtatcttc 1178641 cacggaaatg gttttgactt cgagcataat gttcctcctc atgattgttt ttctatatcg 1178701 taacacgaat ctcgttgaaa aagactgccc gattcgatca ggcagtcttt tggaaattaa 1178761 tgcaaaaaga tattttggcg ctgctcatct ttttgctgaa tatatgatgt gagctcagcg 1178821 gttaagtcag atctgaggaa aggcgttatc aagtagatgc cgttaaacag ctcgcatgcc 1178881 gtatccagca gggagcgtgc aattgcaagg ccttccgcct tttgcttttc tttatcttca 1178941 ccggcatggg ccattttttc gcgaatcgta tcagacagct taatgccggg aatttcatta 1179001 tggatgaatt cggcattccg gctgcttgtc agcggcatga tgccgatata gatcggcgtc 1179061 ttcagatgtt ttgtttcgtt atggatatcg acaagctgct gctcggaata gacaggctga 1179121 gaaacaaaat aatctgcgcc gcaatctatt tttttctcaa gccgttttac cgctttatcc 1179181 agatggcgga cgttaggatt aaatgcggcg gcaactgaga aattcgtttt cttgccgagc 1179241 ggttttccag acagagacag accttcattg aattgtttga tcagcctgat taaatcaaaa 1179301 gatgttaaat catatacaga cgtcgcccca ggaaaatccc cgattttaga agggtcacct 1179361 gtaatagcaa gcacgtcatt cagccctaac gtatcaaggc ccattaaatg tgactgtaag 1179421 ccgataatgt tacggtcacg gcacgtaata tggacaaggg aacgcatatc gagctgctgc 1179481 ttgacaaggg cgccgcaggc aacattgctg atccgcgggg tcgccaaaga attgtcggcg 1179541 agtgtcaggg catcgattcc cgcttctttt aattcagcag cagcggacag aaatttgtca 1179601 aagcttagtt ttttcggcgg gtccagctct acgataatag agcgtttttt cgctgcgatc 1179661 tcatccaggc cgggctcggt tcgctcgtga tgaacagaaa tgaattcttt cgcccgggtt 1179721 ttgacttctt tttccgtaat cggagccagc ccgccaaccg cttccgccat cgccctgatg 1179781 tgattcggcg ttgtgccgca gcagccgccg ataatccgcg caccttgctt acggaattct 1179841 gacgcgctgt tttgaaaata cgtgtcgtct gtttcataga cgagccgtcc ctcttcaagc 1179901 gaaggaagac tgctgttcgg ataaacggat aagaatacgt catcaaaaat cggcacttcg 1179961 cttagcgctt caatcatgtg ataagggccg aggcggcagt taatgccgac aatatcagct 1180021 ccgagatccg caatcgagcg caatgcgtca gaaagcggcg ttccgtcctg caatacgcct 1180081 tgctcgtgca tggagacatt gagcataatc ggaagatcag tctctttgcg cgcgattttc 1180141 agcacttcac gggcttcttc caaatcataa tatgtttcta acagcaagcc atccggctct 1180201 tcatgcagca gcagatacag ctgctcgcgg aagctgcgct taatttcgtc aagactgtat 1180261 gcgtttttat taaatgtgcg tatgccgccc atcgttccaa gcacgtatgc atcgcctgct 1180321 gaagcccgcg cgatctttac ggcctcctga ttcatttttt tgatgtcatc ctcaagcccg 1180381 tgtctggata atttaatata gttggctccg tacgtattcg tttgaataat gttggctccc 1180441 gcttcaacgt acgctttatg tatgcgctga atttcctccg gctttgaaat attgagctcc 1180501 tcaaaacacc tgtcaatgcc ataggagtag aggagcgtcc ccatggcgcc gtcaccgatt 1180561 aacacctgtc tttgcaaatc ttctaaaagt cccattgtct gcctccttta ttcacatcag 1180621 caaggaaaaa agagaaataa aaaaagtcct cttaagaaga agactttgtc agtgattttg 1180681 tctcttctta tcttccaagc tgttcgagct tgctggattt agcaccttgg tcatggctga 1180741 tcgccattac accggttgct gaagcttcgt cgggccagtc cctctgcttc tcttgataag 1180801 aacggatatg aaattttcgt gtcaggaagt gccaaaagat atctggcgtt tttccctttc 1180861 tccaaattta ccgaaaataa agacaataat caataggaat cagaaaattt atctgaaatt 1180921 tataaattga acgtcaattg gcagatctgc tccccgtaca gctgagataa tctgctgcag 1180981 gtcatctttg ttttttccgg tgacacgcac ttgatcatcc tgcacctgag actttacttt 1181041 cagtccggag tttttgatga tcgtattgat tttttttgcg ttgtccttgt caatgccttg 1181101 aacaagcttt gcacgctggc gcaccgttcc gcctgacgcg ttttcaacct tgccgtaatc 1181161 aatgtttttt gtcggtacgt ttcgtttaat caatttgctg accagcacat ctttcagctg 1181221 gcttaatttg aattcgtcat cggaaacgag gaccagctcc tctttatcta aagaaatgtc 1181281 gcttttgctg cctttaaagt catatcgggt actgatttcc ttcagtgcga tttggattgc 1181341 gttttgcact tcaggcaatt ccaccttgga tacaatatca aatgaacttt cttttgccat 1181401 atgaaaacct ccataacatt taacttatgt gttgattata gtagaataaa gagaaacttc 1181461 caacagaaca aagaatcaat ttgtgatgat tggaaaaaat gttaacaaaa tccgcagaga 1181521 ataagcggaa caggaaggac gatagcatga gaccagggca gcaattaacc ttgagtatag 1181581 atcaccaaac cgacttcggt tactttttaa ccgatgggga agatacgatt ctcttacata 1181641 acagtgaaat gactgaggat atcgaggaca gagacgaagt agaagtcttt atatacgtag 1181701 accagcagga aaggcttgcg gccacgatga aaattccgat catcagcgcg gatgaatatg 1181761 gctgggttga agtggtggat aaagtggaag atatgggcgt tttcgttgat gtcggtttat 1181821 cgaaggacgc actagtcgca actgagcatt tgccgccgta cgaagatgtc tggccgcaaa 1181881 aaggggacaa actttactgt atgctgaagg tgacgaaccg ggggcgcatg tttgcgaaac 1181941 cagcgccgga agatatcatc agcgaactgt ttaccgacgc ttcagaagat ctgatgaata 1182001 aagagctgac aggtacggtg tacaggctga tcgcatcggg ttcattcgtg atcacggatg 1182061 acggtatccg ctgttttatt cacccgtcag aaagaaaaga ggagccaaga ctgggttcaa 1182121 gagtcacagg ccgggtgatt caagtgaaag aagacggttc agtcaacttg tcgctgcttc 1182181 cgagaaaaca ggatgcaatg tcagttgatg ctgagtgcat tctaacgtat atgagaatga 1182241 gaaacggtgc catgccgtac agtgacaaaa gccagcctga cgatatcaga gaacgtttta 1182301 atatgagcaa agccgccttt aaacgcgcgc tgggccattt gatgaaaaac ggaaaagtgt 1182361 atcaggaaaa tggatggaca tacgagaaaa aatagcatga aaacggctcg cctgcagcag 1182421 actgcggagc gagccgtttt tttatgtcta gtttaattca tcaaccagcg ttctgattgc 1182481 catttcgcga tccacattgt ctgaaatcgc aatcggcgta atatcaatgg cgagaatgat 1182541 cagaatcagg gcacctgctg cagcaacata agaaacataa tagaaatagt tagcggtatc 1182601 aacagtgttg acaagctcgg cctgaactct ggatgtatca tccttagaag cggcgatttc 1182661 ctttgcagct tctacttttt cttcaacgat ttgacctgct tttttcagca gttcatccac 1182721 tttcaatgca tctttgctgt aaacagcttt cttcaggtta tcaaaaaagt cagcatcctc 1182781 ttttttaata tcagcgacaa cctgattggc aaaagccttt gcctgttttg tgttgagttt 1182841 gtctgtcatc gctttattaa agacctctgg aagctgtttg ccaacttccc cttgggcaaa 1182901 cacaaagcct ttaaaaattt cctcacctga atactcaagc tgctttgcct gtgccacact 1182961 ttcttgctgc ttcaccaaaa acacagtcgt caccaataca accgacaaaa atactagaaa 1183021 cgccttcttc aaactgaaac ctctcccttc ttgtgttttt tattccacaa cagtctgcga 1183081 atatatgtaa attgaatcgt ggaatcgata ggagtgagat acaatatcaa aatgccggcc 1183141 atgataatcg aaaaactgat gaggcccagc atgactgcaa aaatctcatg cataaaaaca 1183201 gcgatgatca aaatcaatct ccaatgcttc ttcggcgcaa acagtgccgc gaagatgaca 1183261 atttgaacca gcagcgtccc ccatgtcgga atcaccacga acggacttgt tacaattggc 1183321 ttcgttaacg cctgaaaaaa gccgttgaag ccaatggttt tttcctgggc gaaataatag 1183381 acggccgttc cgtccaccca ttcctgctga gatagcttag cgacggtaga gtgaaaataa 1183441 agcaccgcca cttggattct gatcacaaaa taagaaataa aagctgttat ttttccaagt 1183501 gttcttttgc cctctatagg tctcgtactc caatgccatt ttctcggatc ggtcagcgtg 1183561 atgggaagca ataaaaaggt catgactgct gctgcctgct cgcctccgtc gatgacgatc 1183621 agcgatgact gcaggctgta actgacatac caatgcagaa ccccggtgat tctggggcgc 1183681 cagccaatga caacaagcac cagaatggca atgcagaccc atctgaaaag atttaacatc 1183741 atatagttat tttcgccgag acaaaagaga ctgagattca ttttacaagc tggatagctg 1183801 ctgatcccgc tggctggctt cataatgagg ctcgggtgat tgatgagcag cgtcagcagg 1183861 ctggatagcg caatgatgct tcgcgcgagg ccatatacat ttgtccacgg gtttctttcg 1183921 tcccatctgg tgatggtctg ttttatgttt tcgagcatga gatcacaacc ttgactatgc 1183981 tttttacctg ataagacgaa ggggtatatt tagaatagct ccaaggaaca atatcctctt 1184041 tcgtcaaata gtagctgcca caaagcagcg ggcggggagc gggtgttttt aattgcacgg 1184101 ttttggcttt gcttttgcat gcgccgaggt ccttttcttt acatgctgtc cactgttcct 1184161 tgccgacttg gctgtagatc acgcccattt caacgccttg tgaccgccca taccgataca 1184221 ggccgaatag gttgtcagcc ctcatattgg gccatctgac cttggcgctg gcattttcag 1184281 cctcatataa gccgattgca gtatcacgcg gatttttgct aaaaaagccc cagccctgag 1184341 ggaggatgct ggacatgaga aatttggagt cctttgtcag cggaatcggg gttgtcccta 1184401 agctgccaat aatagaaaac agaaatagcg aaccccaaag gattgaaaaa atgacaaaaa 1184461 atgatatcga tttctgcatt cgactgctcc ttttaacctg aagaatcgtt tttacacttt 1184521 tcataatata aaaacattta tgtaataaaa aggttaaaaa gtatgagaaa ttccattttt 1184581 gttaaaagga aaaacaggac attttacact gctatatgtg attgatatat agtgtttttt 1184641 tcgatatatt taaaccatga aaacgaatca agttaatgac cgctggattg ttcaatttcg 1184701 aaaagggatt ttcgagctgg ccatcctatc ccttctgcgt tctaaaccga tgtacggtta 1184761 tgagctgacg tcatccttaa aaaccacctc ggcgctggct atttcagagg gagcgattta 1184821 tccgattttg aaacgtatga ccgagaaggg atggatcgaa tttttttggg aagattcact 1184881 ggacggcccg aaaagaaagt attacaaaat gacgcaaaaa ggagaagaaa tgttaaaaga 1184941 acggctggag aaatacctgg aaacccatca agccttactg tctttatcgg gggatttgct 1185001 atgaatggac agcttatcat tgaccgatac atggaggaac taaatgcaga gctggcgaat 1185061 atgcctgatg tagagagaga aaacgctatc gacgaattaa aggggcatat caccgctttc 1185121 gttcaagaca gaatcaaagc cggccttagt gaagaggaac tgcaggaagc tgttgaatct 1185181 gaattttctc atccgaagga gcttgccgaa ttgatgatgg gtgatggggg agagacgaaa 1185241 aggaggaggt ctttattggg caaaagctgg atttcggtcc ttctcattgt cacgattatc 1185301 gccctgccgc tgctgccgtc cgacttcaga catctgccgc tggctgttta tttaatggtg 1185361 ctcgccggat atgtatggaa gcggaaaaaa ttggtgatgt ttgcaggtgt cagaaaaaac 1185421 aaaatgcgct ctcaaaagga gattgtcaag atttcgcgag tcggtgcggt ttatctgctg 1185481 tttttagcag tggtgctcct tttgagcccg ttcctcaatg cgcttgtcgt cctgctgctg 1185541 attgcagtaa gctgcgccgc tttttttctt tttcttaaca tcaagtaatc ttgtaggagg 1185601 ctgtaagatg gaaatcagca tcaattatct attaattgtc atcgcgcttt tattctttgt 1185661 ggttgcctat tttgtcggaa tcaaaaaaca aacctggatg ttggctgggt ttaacgaggc 1185721 gcgtatacgg gataaagatc ggctggccag aatagcaggc tactttttct tgaattccgg 1185781 tttgttcatt ttgctgaata gttttatctc atttcaaggt caggagcagc tcatacctcc 1185841 gcttatactg gcatatggag caggggttat tatttatgtc aataaaaaat tagtagagta 1185901 gaaaaagaag ggcagagcga aatatctctg cccttctttt ttgggaaaat aagaacgaag 1185961 caccacatac aagtttttgt atttttgata ggatgaagaa aaatggtaga ttccaaaata 1186021 ggaaggatgt ggtgttttgc gcaacttgac caagacatct ctattactgg ccggcttatg 1186081 cacagcggcc caaatggttt ttgtaacaca tgcctcagct gaagaaagca tcgaatacga 1186141 ccatacgtat caaacccctt catacatcat cgaaaagtca ccgcagaagc cggtacaaaa 1186201 cacaacccag aaagaatcgc tattttccta tcttgacaag catcaaacgc agtttaagct 1186261 caaagggaat gcgaacagcc attttcgcgt ttcgaaaacc ataaaggatc caaagacaaa 1186321 acaaacgttt tttaaattaa cggaggttta caaaggaatt ccgatttacg gctttgaaca 1186381 agcggtcgcg atgaaggaaa acaaacaagt gaaaagtttc tttggaaagg tgcatccgca 1186441 aatcaaggac gtctccgtca caccgtctat ttctgagaaa aaagcaatac atacagcaag 1186501 gcgtgagctc gaggcttcca ttggaaaaat cgaatatctt gatggggaac caaaaggcga 1186561 attatatatc tatccacacg acggtgaata tgatctcgcc taccttgtga gactctcgac 1186621 atctgaacct gagcctggct attggcatta tttcatcgat gccaaaaacg gaaaggtcat 1186681 cgagtccttt aatgccattc atgaagcggc aggtacagga atcggcgtgt caggtgatga 1186741 aaaaagcttt gacgtcacag aacaaaatgg gcgcttttat ttggctgacg aaacaagggg 1186801 aaaagggatc aatacatttg acgcgaagaa cctgaacgaa accttgttta cgcttttgtc 1186861 tcaactgatc gggtatacgg gcaaagaaat agtcagcggc acgtccgtat ttaatgaacc 1186921 tgcggctgta gacgcacacg caaatgcgca agccgtttac gattattaca gcaagacatt 1186981 tggccgtgat tcttttgatc aaaacggagc aaggattacg tctaccgtgc atgtcggcaa 1187041 acaatggaac aatgctgcgt ggaacggtgt ccagatggta tacggggatg gagacggttc 1187101 gaaatttaag ccgctgtctg gatcgctcga cattgtcgcg catgaaatca cacacgcagt 1187161 cacacagtat tccgccggtc ttttatatca aggagaaccc ggtgcattaa atgagtccat 1187221 ttctgacatt atgggcgcga tggctgaccg tgatgattgg gagatcggcg aagatgtcta 1187281 tactcctggt attgcaggag attcattgcg gtcattggag gacccatcta agcagggaaa 1187341 tccagatcat tactcgaacc gctacacagg aacagaggat tatggcggag tccatatcaa 1187401 ttcgtccatt cacaataaag cagcttatct tcttgcagaa ggaggcgtgc accacggtgt 1187461 acaggttgaa gggattgggc gtgaagcaag tgaacaaatt tactatcggg ctttaacata 1187521 ttatgtaacg gcatctacag atttcagcat gatgaagcaa gcggcgattg aagctgccaa 1187581 tgatttatac ggtgaaggct cgaagcaatc agcttcagtc gaaaaggcgt atgaggctgt 1187641 cggcattcta tgagcaaaca aaaacagtca ggacacagag tctgactgtt tttgtttgct 1187701 cattttctta aaaagaatat cgccaatgta cctggaccgg catgcgagcc gatggctgaa 1187761 ctgattggat gcataatgat ttctttcggc ttgaacgctt cctcaatcag gtgtttcata 1187821 tccgtggctt tttctttgtt cgcggcgtag ctaatcccga cggtttgatt gctccaatca 1187881 tccccgcgct ctttcataag ctcgatgatc cgtttgaaaa gtttcttctg tccgcgaatt 1187941 ttttccagag gcacaagctt gccgtcctcc atctgaagca gcggtttaat attcaacagg 1188001 ccgccgacaa aagcggacgt tttggatatc cggccgcccc tcgcgagata tgttaaatca 1188061 tcaacggtaa aaatgtgttc aagctggctg caaaagttct ttacagacgt ttcaatttct 1188121 tgtattgtat tcccgttgat acagagatcg gcagcatgcc ggacagccag accgtatcct 1188181 aatgaagcgc atttggaatc aatgacccgc aaatcgaaat cggggaattc ctccttcact 1188241 tcattggcga tcattacagc tgtctgatac gtgccggaga gacctgagga aaaggcaatg 1188301 taaagagcgg gatcacctgt ttcggcatat tgcaaaaaca catttttaat cgtttgcggt 1188361 gaggcttggg acgtcttagg cgtttctcca ttttgcatcg cttcaaatat ttgatccgca 1188421 tgaattgtga ctgcatcttc gaattcttta tcgccgagag aaaccctgag cggaataaag 1188481 ccaatgcctt tttcttcaaa ataagaacga ggcaaatcag tggcgctgtc agcgatgaga 1188541 tgaactgtca tattgcttcc cttctttccg ttatcgctcg ttatcatgag agttaagcca 1188601 actatatcat attaatttgc caaaatcgtg ttcaaatatt tgttttaagg gaaaacataa 1188661 taaagaagaa agagcggagg aacatgccat ggtactagat caaacaaaaa aattactcat 1188721 cgtcatcatc ggcgctttac tcaatgctgc cgggctgaac ttatttttga tacctgcaga 1188781 tgtatatgcc agcggattta caggtgttgc ccagctttta tcaagcgtcg ttgatcaata 1188841 tgcccccttt tacatatcga cgggaacgct cttgttcctc ttaaacattc cggtcggtat 1188901 tttaggatgg ctgaaggtcg gcaaatcgtt tacagtgtac agcattttaa gtgtcgcact 1188961 cactactctg tttatgggga tcctgccgga aacaagcctg tcacatgaca ttttgctgaa 1189021 cgcggtgttc ggcggcgtca tttccgcagt cggtatcggc ttaacattaa aatacggagc 1189081 ttcgacaggc gggcttgata tcgtcgccat ggtacttgca aagtggaagg ataaacccgt 1189141 cggcacgtat ttcttcattc tgaacgggat tatcatcttg acggcaggat tattgcaagg 1189201 ttgggagaaa gcattatata ccctggttac actatatgtg acaacgaggg tgatcgacgc 1189261 cattcacact cgccacatga agcttacggc aatgattgtg acgaaaaaag cggacgaaat 1189321 caaggaagcc atttacggaa aaatggtgcg cggcatcaca actgttccgg caaaaggagc 1189381 atttacgaac gaacagaaag aaatgatgat tatcgtcatc acgaggtatg aactgtacga 1189441 tttagaaaag atcgtcaaag aagttgatcc aaaagcattt acgaacatcg ttcaaacgac 1189501 agggattttt ggtttcttta gaaaagactg acgaaagcag gtggaagtcg tgaaacggct 1189561 gcttgtgatg ctcctccccg tgctgctttt gataggctgc gggaaagatg agcagacaga 1189621 acccgataag gaggtatcag gcggaatgga gaatcaagag gttgttttat ctattgacgc 1189681 aattcaggag cctgaacaaa tcaagtttaa catgtcgctg aagaaccaaa gcgaacgtgc 1189741 tattgagttt caattcagca cagggcaaaa atttgaactt gtcgtgtatg attctgagca 1189801 caaagaaaga taccgttatt cgaaagaaaa aatgtttacg caggcttttc aaaacctgac 1189861 gcttgaatct ggagaaacat atgatttctc tgatgtgtgg aaggaagtcc ctgagcccgg 1189921 aacctatgag gtaaaggtga catttaaggg cagggcggaa aatctcaagc aggttcaggc 1189981 tgttcagcag tttgaagtca aataagaggc tatggcgagt cgccatagcc tttttttatt 1190041 gcagtttgtc cagctgattt tgaaattgat gcaactgttg acgttccgca tctgtcgaat 1190101 tggcatacgc agaagataca gcatttttgg ctctcagaat cgcttgctcc tgatcgcctt 1190161 cctcaaagcc gtttgtcacc atgaccgcct gttgaacaaa tgattttgcc tgctgaaaca 1190221 gttcatttct catttaatat tcatactgcc tttcagccga gtctcgtgcc gcggcatgct 1190281 ggtgagcttc ttctaaagta gaccgatatg gaaatcttgc ggcgtgtagc ccgatggagt 1190341 ctttaccctg ctgaataaac cttctggatt tgcttcgttt acccattttg agactgcccc 1190401 cttccatact ttgacgagat gagtcgtctt caatagtatg gtggggtaaa gtaaggttta 1190461 tgagtgggaa aaattaatac ggaccttctt taaagtgaga aatattcttt caaaaacctt 1190521 gccacgccgt cctcttcatt tgtggccgta gttcggttgg caatctgctt gaccgcgtca 1190581 attccatttc ccattgcaac gccgcagcct gcaaattcaa gcatttccaa atcgttatcc 1190641 tcatctccaa aagcaatgat ccgctccctc ggcacgccgt aataatcgct gattttctgc 1190701 aggccgaccg ctttattcat gccgcttttg ataatttcaa tgacatgcca aggagcggcc 1190761 catcttctat ggtcgatcac ctcggcatgc acatccgata aatatgagcg tattgccggc 1190821 acatcctctt cctttgcatg tatgagtacg gacgtcacat cttcaccgag attttcccgc 1190881 aagtctccga ccgttacatt tgttgtgttc atgttaaagg catctatcag gtgctcatca 1190941 tggtaatgaa agtatacgtc gtcaatcact tcagcaagca cgttatgtac gttgtagctc 1191001 tcgctgatat ccacgagctg tttgacaaca tcaagcggca gtgacgtatg ataccgtccc 1191061 cagctgtcgt cttgcggatg atggacaaat gctccgttaa aattgacaat tggcgttgtc 1191121 agctccatct gctggtagta catggaactt gaacgatacg gacggcctgt tgagatgcag 1191181 acataatgcc cgtcatcttt taggcgctgt atcgtatgaa gggtgttttc agatatggtt 1191241 ttatcatcct ttaataatgt tccatctaaa tctaatgcga ttaaataggg ttttgtctcc 1191301 atgaaaagct cctttaacct tagattttgc ttgttttgcc ttacttacag tgtagctttt 1191361 taccatcttt attgtctaca tgttacactt atgattatgg ttatcctaag gaggggcaca 1191421 ttgtgataca aattgagaat caaaccgttt ccggtattcc gtttttacat attgtaaagg 1191481 aagagaacag gcaccgcgct gttcctctcg tgatctttat acatggtttt acaagcgcga 1191541 aggaacacaa ccttcatatt gcttatctgc ttgcggagaa gggttttaga gccgttctgc 1191601 cggaggcttt gcaccatggg gaacggggag aagaaatggc tgttgaagag ctggcggggc 1191661 atttttggga tatcgtcctc aacgagattg aagagatcgg cgtacttaaa aaccattttg 1191721 aaaaagaggg cctgatagac ggcggccgca tcggtctcgc aggcacgtca atgggcggca 1191781 tcacaacgct tggcgctttg actgcatatg attggataaa agccggcgtc agcctgatgg 1191841 gaagcccgaa ttacgtggag ctgtttcagc agcagattga ccatattcaa tctcagggca 1191901 ttgaaatcga tgtgccggaa gagaaggtac agcagctgat gaaacgtctc gagttgcggg 1191961 atctcagcct tcagccggag aaactgcaac agcgcccgct tttattttgg cacggcgcaa 1192021 aagataaagt tgtgccttac gcgccgaccc ggaaatttta tgacacgatt aaatcccatt 1192081 acagcgagca gccggaacgc ctgcaattta tcggagatga aaacgctgac cataaagtcc 1192141 cgcgggcagc tgtgttaaaa acgattgaat ggtttgaaac gtacttataa agcactaagt 1192201 tattaacaag agctgaattt acgttatact gtagaaaaaa ggagtgaggg aacgtggaag 1192261 aagcattaaa agaaaacatc atgggcgccc tggaacaggt tgtcgatcct gagcttggcg 1192321 ttgatatcgt gaacctcggc ttggtatatg acgttgatat ggatgaagat ggcttgacgc 1192381 acatcaccat gacgctaaca tcaatgggat gccctttagc gccgattatc gtggatgagg 1192441 tgaaaaaagc attagcggac cttcctgaag tgaaagacac agaggttcac attgtatgga 1192501 atccgccttg gactagggat aaaatgtcca gatacgcaaa aattgcgctt ggcattcaat 1192561 aaaacaaaaa aggacagcct gacatgtgag gctgtccttt tttacagctg aaaggagtga 1192621 aaggaaatga tgtacctgct ggcagtttta tgcccgccgc ttgctgtttt gttttcggga 1192681 aaaccgtttc aggccttgct gaatctcata ttgacctgta tcttttggct gccgggcgcg 1192741 attcacgcct gctttatcgt cgccgaccgc cgtgccgaaa aacgggcaag aagataattt 1192801 ggaaaaatga ggacgcagtc atggtataat ggtcataaaa acagcaggga gagcactatg 1192861 aaaaagaaat tgcttgcatt cgcgctttgt actggcgcgt atgcggccct gtttgcgtac 1192921 tctgtgaact cagagcaaaa aacagccaca agcgagatga cggatgtcag ccgcctgatg 1192981 cctgtaaaaa taaagcagac agtgaaaggg caggaagagg aaatgctcat tgacacagtc 1193041 aaagaggcaa atcgaaaaaa cataaaaatt tcaatcgccg gggcccagca ctccatgggc 1193101 ggccatacat attatgagga cggcatcgtt ctcgacatga cgggctacaa caaaatcctg 1193161 tcactcgatc aagagaagaa aaccatcagg gtgcaaagcg gtgcaacgtg gaatgatatc 1193221 cagaaatacg tgaatccata cggactcgcg gtaaaagtca tgcagtcaca aaacattttt 1193281 acaatcggcg gatctctcag cgcaaatgca cacggacgtg atattcgcta cggctcgcta 1193341 attgatacag tcaaatcatt ccggctttta aaagctgacg ggatgattat cactgtcact 1193401 ccaaaagatg atttgtttac ggcggtcatc ggagggtacg gcctttttgg cgtgattctt 1193461 gatgtaacgc ttgagctgac agatgatgag ctgtatgtca tgaagacaga aaaaatgaat 1193521 tacagcacat actcagacta tttttcaaag catgtaaaag gaaatccaga tgtccgaatg 1193581 catctggcgc gaatttcaac agcgaaaaaa ggatttctga aagacatgta tgtcacgaat 1193641 tacgtattgg ctaatcatca ggatcagctg tcctcataca gcgaacttaa agaagacgag 1193701 tatacgggag ccacaaagtt tgcactcggc ttgtcaagac ggtatgaatg ggggaggaat 1193761 tggctgtggg acacacagca atcctatttc ctgagccaga acggcacaga gatttcacgc 1193821 aataacgtca tgcggtccga atcaaagttt cttgagtatg aaaacaatga caacacagat 1193881 gttttgcaag aatactttgt gcccgtgaag gagtatgggt cctatattga tgacctgaga 1193941 caaacgctgt cggacgaaga tctgaacctg ctgaacatta cgatccgcta cgtgcagaaa 1194001 aatgaaaagg ccgacctttc ctatgcgaag gacgatatgt tttcgctcgt actattaata 1194061 aacgagggct tttcaaaaga agaccaggca gataccgccc gaatcatcag gcgcatgaca 1194121 gacgttgcca tcaagcacgg cggcagctat tatctgcctt atatgaccta ccagacaaaa 1194181 gcgcaaatga gacaggcata tccgaaaagt gaagcgtttt ttcagaaaaa acgaacctat 1194241 gacccggatg agcgctttat gaattacttt tatcagaggt ataaataatg gggaaaaaca 1194301 aattaaaatg gctgacatta tcacaaagca gcgtgttttt cgcaagcagc ttaatctttc 1194361 cgttttatat tctgtttgtg aaaaatatcg gctcaagcta cacacagttc ggtttttcct 1194421 acggattgtt cgggttgagc ggagcgctta tttacccgct cctcggacgg ctgtctgaaa 1194481 ggtttgacag ccgttatttt ctgcttctga actcgtgggg gatggctgtt ctgcttttat 1194541 atgtcccgca tatcggaagc gtcgttcaag tgtatatcgt ccaagtgctg ttagggctct 1194601 ttggagcgat gcaaaagcat ggagaaaaag tgctgatcgc taattttaca gacagtggag 1194661 agcgtggaaa gaagatcggg aattaccatt tttggacagc tgtcttttca gcagcagcca 1194721 ttatgctcgg gggctttctc gctgactttt tcacagtgca aatgattttt tatgcaagct 1194781 ctattctata ttttttgagt ggattgatga tgatgaaaac aggctgacgc ggtcagcctg 1194841 tttttttatg cggctgaaat gcggcaccgc atcaacgttt ttgtgctgga gtcgtgctga 1194901 ttttttttga gcggaattcc cattgaacag aaaatttata aatgaataaa aatattaaat 1194961 atacgattga attaattttt attcatgtta taatgttaaa taatttcaca aagaccaaga 1195021 gggtgaactt gttttgaaaa taggaattgt aggtgctaca ggatatggag gcaccgaact 1195081 tgtcaggatt ctttcgcatc atcctcatgc agaggaatgc atactttatt catccagcgg 1195141 agaagggaat gtctatagcg agggttatcc tcatcttacc ggcttagcgg atcagcagct 1195201 gaagccgatt gatatgaata cgatcaaaca cgaaatagat atcatgtttc tcgctgcgcc 1195261 gcccggagta tcaagtgaat tgactccaaa gctggcagac gcgggaatta cggttattga 1195321 tctgtcaggt gatctgagga taaaagaacc ggctgaatat gaaaaatggt ataaacggac 1195381 agcggcaccg aaggcggtga ttcaagaggc ggtatacggt ctggcagaac tgaatcaact 1195441 gcaaattcaa caggcgaaac tcattgccaa tccaggctgt tttccaacag ctgttttgct 1195501 tggcctcgcg ccattggctc aaaagaaact gctcgatgaa tctttcgtta tcgttgacgc 1195561 gaagaccggt gtttccggag cgggaagaaa agcatccatg ggaactcatt tttctgagct 1195621 gaacgacaat tttaaaattt ataaagtcaa tgaacatcag cacacgccgg aaattgagca 1195681 ggcgctgaat gaatggcagc caggtctcgg gcccattaca ttttcggctc acttggttcc 1195741 gatgacaagg ggcatcatgg cgacgatgta taccagatta acctgtgacc taaccgcaga 1195801 tgacctgcat gatttatatt cggaatttta ccaagattca tattttgtga gagtgaggcc 1195861 aaaaggtcag tacccgcaaa cgaaagaagt gtacggcagc aatttctgtg atatcgccgt 1195921 gaccctcgat gagagaacga acagagtcac gatcgtctcg gtaatcgata atttaatgaa 1195981 gggtgccgcc ggtcaggcag tgcaaaactt taatttgatg aatggctgga atgaagaaac 1196041 tggactcacc atcacgccaa tttatccata gaacgggaga gaatcgaacc atgattcagt 1196101 taagtgaaga tcaaattgta aaagtaacag gtgatgtatc ctcgccaaaa gggtttcagg 1196161 caaagggtgt gcattgcgga ctgcgctact cgaaaaaaga cctcggcgtc attatcagcg 1196221 agacaccggc cgtgagtgca gcagtttata cccaaagcca ctttcaggct gctccgatca 1196281 aagtgacaca agacagctta aagcacggac cgacactgaa agccgtcatc gtcaacagcg 1196341 ccattgccaa cgcctgcacg ggagaacagg gcttaaagga cgcatacaca atgcgggaga 1196401 gctttgcttc acagcttggc attgagccgg agcttgtcgc tgtttcatca acgggtgtca 1196461 tcggcgagca tttagacatg gaaaaaatcc acgcggggat cgaactgctg aaagaaacac 1196521 ctgcgggatc aggcgatttt gaggaagcga ttttaacaac tgatacggtg atcaagcaga 1196581 cgtgctatga actggcaatc ggcggcaaaa cagtcacgat cggcggagcg gccaaaggct 1196641 ctgggatgat acacccgaac atggccacga tgctgggatt tgtgacaact gacgcggcaa 1196701 tcgaagaaaa agcgctgcaa aaggcgcttc gggaaatcac tgacgtttca tttaaccaaa 1196761 tcacagttga cggagaaaca tccacgaacg acatggtatt agttatggcg aatggctgcg 1196821 ccgaaaacga gtgcctgaca gaagaccatc cagactggcc ggtctttaaa aaagcgctct 1196881 tgctcacttg tgaggatcta gctaaagaga ttgccagaga cggagaaggc gcgacaaaac 1196941 taattgaagc ccaagtacag ggagcgaaaa acaatcttga tgcaaacgtc attgccaaaa 1197001 agattgtcgg ctcaaatctt gtaaaaacgg cagtatacgg aacagatgcc aactgggggc 1197061 ggatcatcgg agccatcgga cactccgcag cacaggtgac ggcagaagaa gtagaggttt 1197121 atcttggcgg ccaatgcctg tttaagaata acgaacctca gccattctct gaatctatcg 1197181 ccaaggaata ccttgaagga gatgaaatca ccattgtcat caagatggct gaaggggacg 1197241 gaaacgggag agcgtggggc tgtgacctga cctatgacta tatcaaaatt aacgcgagct 1197301 atcgcacgta ataaagggga gcgaaatgaa gaaaacaatc gtttttaaat gcgggggaag 1197361 cgtcatccgt gagctgtcgg aggaatttta tcaaaatctg aaagagctga gggcgtcagg 1197421 ctggaagctg gcaatcgtac atggcggggg accggaaatc acaaatatgc tgaaacggtt 1197481 aaatatcaag acagagtttt cgggcggaca gaggaaaaca acgaagccgg tgctggaagt 1197541 ggcggaaatg gttttatccg gttctgtcaa taaatttttc gttgctgagc ttgccaaaca 1197601 cggactgcga gccgcgggca tttctggtaa ggatggcggt cttttggagg ctgattatct 1197661 agatccggaa acatacggag aagtgggaga aatcaaaaaa gtcgatgcgt ccatggtgaa 1197721 cgcgctgatg gaaaatggca tcatccccgt tattgcgccg ctgtctatga caagcgactg 1197781 caaaacgctg aatgtaaatg ctgatctggc tgcttcagca gtcgccggag cgcttgaagc 1197841 cgataagctg atgttcgtca cggatgtcga tggaatcatg aaggaaaagc agcgtctgga 1197901 cgtcctgacc cctaaggaga ttcagatgct gatcaagcag gaagtgatca caggagggat 1197961 gatcccgaag gtcaattcag ccttgtcagc tttatcagat caggtgtctg aagtcatgat 1198021 cgtaaacggt aaaggatcat tcttcgcaga acaaaccttt caagggacaa aaattgtcaa 1198081 agcaaaggag gctgtttcat gagcagcttg tttcaaacct acggccgttg ggatattgac 1198141 atcaaaaaag caaagggaac gtacgttgag gatcaaaacg gcaaaacgta ccttgatttc 1198201 attcagggga ttgcggtatc aaatctagga cactgccatg aagcggtgac agaggcagtc 1198261 aaaaaacagc ttgacagcgt atggcacgta tccaacctgt ttcaaaacag tctccaagag 1198321 caagcggcgc agaagctggc agcgcatagt gcgggagatc ttgtcttttt ctgcaacagc 1198381 ggcgcggagg cgaatgaagg tgcgataaag cttgccagaa aagcaactgg aaaaacaaaa 1198441 atcatcactt ttcttcagtc gttccatggc cgcacgtatg cagggatggc tgcgaccgga 1198501 caggataaaa tcaaaacagg cttcggcccg atgcttggag gctttcacta cctgccatac 1198561 aatgatcctt ctgcttttaa agctcttggg gaggaaggcg atattgccgc ggtgatgctt 1198621 gaaacagtgc agggagaagg aggagtcaat ccggcgagtg ctgaattttt atcagccgta 1198681 cagtcgtttt gcaaggaaaa gcaagccctt ctcattattg atgaaatcca gaccggcatc 1198741 ggacggacgg gaaaaggctt cgcatatgag cacttcggac tctcaccgga tatcatcaca 1198801 gtcgccaaag gattgggaaa cggctttccg gtcggcgctg tcatcggaaa gaaacagctt 1198861 ggagaagcgt ttacccctgg ttctcacgga acgactttcg gaggaaacat gctggcgatg 1198921 gctgctgtga atgccacatt gcaaattgta ttccagcctg actttttgca agaggctgct 1198981 gacaaagggg cgtttttaaa agaacagctt gaggcagagc taaagagccc ttttgttaaa 1199041 caaatccgag gtaaaggatt aatgcttgga attgagtgtg atggcccggt tgctgacatt 1199101 attgctgaat tgcagacatt aggcttgctt gtattgccgg ccggcccgaa cgtgattcgg 1199161 ctgctgccgc cgctcaccgt gactaaggat gaaatagcag aagccgtcag caagctgaaa 1199221 caggcaatcg ctcatcattc cgctgtaaac cagtgatttt ttttcgatat aaaggcataa 1199281 aaattcattt ttataattaa ttattcatca agaggtgggc tgttagatgg aaggttattt 1199341 agtgttagaa gatgggacat cgttcagcgg cgagctggac ggtcatgaaa actgcacggg 1199401 agaagctgtt tttttcacag gaatgacagg ctaccaggaa gtgctgacag atccatcata 1199461 taagggacag attattgtat ttacctaccc gctgattggc aactacggca taaatgaaaa 1199521 ggattttgaa agcaagaaac cgcaagtaaa agccgcggtt gtctatgagg cgtgtgatca 1199581 cttttctcat tatgaagcgg tatacagcct caaggagtat ctacagaaat ggaatattcc 1199641 gctgttaacc catgttgata cgagggctgt cgtgaagaaa atccgggcaa acgggacgat 1199701 gggtgcgaca gtcacagcct ctaaagaagg agctgagatt gcccttcaac cagagaatgt 1199761 ggcagagcag gcttccgccc aggaaatcag cacattcggc gacgggaata aacatatcgc 1199821 tctcattgat tttggctata aaaagtcaat cgcatcatca cttgtcaaac gaggctgcaa 1199881 ggttaccgtg gtgccatacc agcaaatgga ggccgtatac aacatcaaac ccgatggaat 1199941 tgtgctatcg aacggacctg gagatccgaa agccattcag ccatatttag gaaagatcaa 1200001 aagcatcatc agccgctttc cgactctagg catttgtctc ggacatcagc tgatcgcgct 1200061 cgcgtttgga gggaatactt ttaagctgcc attcgggcac aggggagcta atcatccggt 1200121 catcgaccgt aagacgaaac gggtctttat gacaagccaa aaccacagct atgtggttga 1200181 tgaacagtcg attaatgaag aagagctcac catcaggttt catcatgtca atgatacgtc 1200241 agttgaaggg cttgcccata aaaaactgcc tgtcatgagt gttcaattcc acccggaagc 1200301 ccatcccgga cctgcggaaa gcgaatggat ttttgatgat tatctaaaga atgtgatacc 1200361 agcaaggaga gaaatcgcgc atgcctaaag acaccagtat ttcaagcata ttagtaattg 1200421 gctcaggccc gatcatcatc gggcaggcgg cagaatttga ttattcaggc actcaagggt 1200481 gcatcgcgct gaaggaggag ggctaccggg taattctcgt caacagcaat ccggcgacaa 1200541 ttatgactga tgaagccttc gctgatgaaa tttattttga gcctctgaca gcagaaagcc 1200601 tgacagccat cattaagaaa gaacggcctg atgggcttct tgccaattta ggcggtcaga 1200661 ccgcgttgaa tttagcggtg gagcttgaag aaacgggtgt tttaaaagag cacggcgtca 1200721 aactcctcgg cacatccgtt gaaacgatac aaaaaggaga ggaccgggaa aaattccgtt 1200781 cgttaatgaa tgaattaaaa cagcctgtgc cggagagtga aattgttgat aacgaggccg 1200841 atgccctcca ttttgcggaa tccatcggtt ttcctgttat tatcagacca gcttacacat 1200901 taggcggaaa gggcggagga atcgcccctg ataaagaagc ctttacagct atgattaagc 1200961 aggcgctatt agcaagcccg atcaatcaat gccttgtcga aaaaagcatt gccggcttta 1201021 aagaaattga atatgaagtc atgcgtgaca gcaataacac atgcattacc gtctgcaata 1201081 tggaaaatat cgatccggtc ggcgtgcata caggtgactc tatcgttgtg gcgccgtcac 1201141 aaacattgac agacgaagac tatcaaatgc tgcggacagc aagtctgacg atcatctcag 1201201 cacttgatgt tgtaggcggc tgcaacattc aattcgcgct tgatccattc agcaagcaat 1201261 attacgtcat tgaagtgaat ccgcgtgtaa gccggtcatc ggctctcgca tctaaagcga 1201321 ccggttatcc gattgcgaag atggccgcga aactggcagt cggatacact cttgacgagc 1201381 tgaaaaatcc gctcacaggc tcgacttacg caagctttga accggcactg gattatgtga 1201441 tcgtcaaatt tccgcgctgg ccgtttgata aattcaaaaa cgcagaccgc aagcttggca 1201501 caaaaatgaa agccaccggt gaagtgatgg cgattgaacg gaatttagaa gcggcgatac 1201561 aaaaggcagc cgcgtcgctt gaattaaaaa atatcgggac acaccttcca gagctcagcg 1201621 ggttgtcaat tgatacgcta tgggatttgg caatcactcc ggatgaccgc agatttttcg 1201681 ttgtcatgga gctgttgagc cgcagcgtct cgattgatga catccatgaa aaaacaaaaa 1201741 ttgatccgtt tttccttcat acctttgaca acatcatcaa attggaaaac cgcctgatgg 1201801 aagcagggag cgatctctct tttgaattat tgaagaaagc aaaggaaaag ggattctcag 1201861 acgcaacgat tgcctcgctg atcagcaaaa cagaagaaga ggtgcgcgcg cttcgcaagg 1201921 agatgggcat tacgccttcc tttaaaatcg tagatacatg cgcggcagag tttgatgcga 1201981 aaacaaacta tttttactcc acatatttcg gagagaccga tggagacatc agccgcaaag 1202041 agaaaaaacg cgcgctcatt atcggatcag gcccgattcg gatcggccaa ggcgttgaat 1202101 ttgattacag tgctgttcac ggtgtgctga cactgcaaga gcttgggttc gaaaccatca 1202161 tgattaacaa taacccggaa actgtcagca ccgattatga aattgcggac cgcctgtatt 1202221 ttgaaccgat gacaacggag catattgtaa acgtggcgga gcaggaaaat attgattttg 1202281 caattgtgca atttggcggt caaactgcaa tcaatgctgc tgaagcgctc gaaaaagccg 1202341 gcattactct tcttggcaca tcatttcaaa cgctcgacgt gttagaggat cgggatcaat 1202401 tttatcagct tcttgacgag ctgggattga agcacgcaaa aggagaaatt gcttatacaa 1202461 aagaagaagc cgcttcaaaa gcgagtgaga tcggctatcc ggtgttaatc cgcccatctt 1202521 acgttatcgg cggaatgggc atgatcattg ttgactcgca agcccagctt tctcagctgc 1202581 tgaatgatga ggacagcatg ccatacccga ttttaattga tcagtatgtg tctggaaagg 1202641 aagtcgaaat tgatttgatt tccgacggcg aggaagtctt tatcccgaca tataccgagc 1202701 atattgaacg ggcaggtgtc cattcagggg acagttttgc cattcttccc ggaccgtcca 1202761 tcacgagcgg gctgcagcag ggcatgaaag atgcggcaca aaaaattgcc cgaaaacttt 1202821 catttaaagg catcatgaac attcaatttg tgatcgacaa tggaaacata ctcgttcttg 1202881 aagtgaatcc gagagcgagc cgcacggttc ctgtcgtcag caaagtaatg ggcgttccga 1202941 tgattccgct cgccacacgt ctgctggcgg gagcgtcctt aaaagatcta aatccggcag 1203001 ttcaaaatca tcatggagtt gccgtgaagt tccctgtttt ttcttctcat gcgatccagg 1203061 atgtggatgt caagcttgga ccggaaatga aatcaacggg agaaggcatg tgtgtcgcat 1203121 atgattctaa cagcgccttg aaaaaaatct atacaagagt ctggagtcaa aaaggaagca 1203181 tttatttgca aaacgttccg gaagatgtga aggagttagc agaaaacgca ggttttacaa 1203241 tacatgaagg aacatttgcc tcatggatgg aacaggaagg aaactcgctc cacattaatc 1203301 tgagcggttc tgaagaagca cgcaaagaac gtttggaagc catgacgcac ggcatccccg 1203361 tctttacaga agaagaaact gtgcgggcgt ttttacaaag cggttcaggc catccgcagc 1203421 ctgtatctct caaagacctc tataaaaagg aagtggcatc atgcacacag tgacgcaaac 1203481 cagtttatac ggaaaagatt tattaacgtt aaaggacctt agtgaagaag atataaacgc 1203541 cttgctcgca gaagccggtg agctgaaaca aaacaaaatt cagcctatat tccatggcaa 1203601 aaccttggcg atgatttttg aaaaatcatc aacgcggacc cgtgtttcat ttgaagcggg 1203661 catggcgcag ctgggcggga gcgccctctt tctaagccag aaagatctgc agctggggcg 1203721 cggtgagact gtcgctgata cggcaaaagt gctgtcaggc tatgtggatg ccatcatgat 1203781 ccggaccttt gaacatgaaa aggtggagga acttgccaaa gaagctgaca ttccggtgat 1203841 caatggactt accgataaat accacccatg ccaggcgctg gcggatctct tgacgattaa 1203901 ggagataaaa gggaagctta aaggcgtaaa agtcgcgtac atcggtgacg gaaataacgt 1203961 ggcgcactcc ttgatgatcg gctgcgcgaa aatgggctgt gatatctcga tcgcttcacc 1204021 aaagggatat gaagtgttag atgaagcagc tgaagcggca aagacatatg cacttcaatc 1204081 cggctcttct gtcacgctga cagatgatcc gattgaagct gtaaaagacg cggacgtgat 1204141 ttattctgat gtgtttacaa gcatggggca ggaagcggaa gagcaagaac gtcttgctgt 1204201 ctttgcgcct tatcaggtga atgcggcgct ggtcagccat gccaagcctg actatacatt 1204261 tttacattgt ctccctgcgc atcgcgagga agaagtgact gcggagatta ttgacgggcc 1204321 gaactctgca gtgttccagc aggcggaaaa ccgtcttcat gtgcaaaaag cactgctgaa 1204381 ggccatttta tataaagggg aatcatcaaa aaactgctga gccaaactca gcagtttttt 1204441 tgatggcaac atattcacag ccgcttaggc gcatactaca gcaaaaagga aaaggaggaa 1204501 aaacagtggg acagcagcac caattccggc ccggacagaa agcgcctaat aacggtgtct 1204561 acgtagaaat cggcgagaca gggagcatgg ttaaaaaccc tcaaaaggtc catctgtcag 1204621 caggggaaat gttccccgaa acatcaaacc acaaccggct gtggacctac aaaagaaagc 1204681 cgtgaccact aaaaaaccca aaacaataaa tgttttgggt ttttggcttt ttaatgctgg 1204741 cttgcatttt tgttcatagg catgatttct gctaaaacca tgattaagac atacagtaca 1204801 acagcaatga cagatgatgt tttgaaatta tacgtaacgc tgttcatgct tgcaaccaag 1204861 tagcatgcca tatgtgataa aaggaacgtc caaataaagg caataatata tcgcacgttt 1204921 ccacctcgtc cttctcattc tattctaaaa gttatcatac catacaaaaa gcgaaggggg 1204981 aatccaattt tagcagaaag tgaggtgaca aaagagtctg attcgtcaca ctttaatggt 1205041 aaaatataaa acgtcaatca gtataatagc caaaaatgta aaaggctagg actttacctt 1205101 attcgtttct tttctattta cataagatag cgtgagatga agtgtgaaag gaggcgggca 1205161 agcgatggga ataacggaaa gatactttca actgggaacg gagcataatg tcattcatct 1205221 gccctatcgc ccgaacggct tcggcatctt tatcttgggg gacagaaccc actttgtcgg 1205281 acatgattca agcttttggc agcagcatta tggcagaaat cagcttctga gcatgttgat 1205341 gaatgaagga tacactcttt ttaacagcaa tctgttcgga aggcattggg gggcggaaaa 1205401 agcagtcacc tatgccaaac agctgataca ttctgtgctg aagcaggaaa tcctcaatcc 1205461 gaagattcat attttagcag aaggcatggg tgctctcgtg gccgatgaac tgcttcgttt 1205521 ttccccggat catatccgct cagccgcaat gttgaatcct tgtctcgatc ttcaggcaca 1205581 ttatgaatcg gaaaaagaaa ataaattttt ctataagcaa tttttgaaag aagtatcgaa 1205641 aagctacgga atttctgaaa aagaagcgga agcgattcgt tataaaacaa ttcaaagcta 1205701 cccgagcggc gtaccggttc atatatggca gcgtatgacc ggagctccat atccctacag 1205761 cgtacatgcg gaagttttca aggaaaaaca gcaaaagcaa ggctcaccgg tcgacatgac 1205821 atttcattta tttgagcatc caagcagaat ttatgcatca atttgcaaat tctttcatag 1205881 tcatgaaaaa gaattataga gaatataatg acaacagcct tctcttttgc ggaggctgtt 1205941 ttgttttggg aaatgaaaaa ccggaagggc ggcagatgca atggaatcaa cgctgattgt 1206001 aggtgcggac gaatttttcg gcctttcatt atgtgagcga atgatggatg aaggcataca 1206061 tgttgacgtt gttctggcgg aaacagaaga taaaatgaga caaatgtact tagaagaaag 1206121 actcatgtgg cttgggagaa atgaactctt tcgccagctt gaacacattg gagaccaaaa 1206181 ttatgataca atttgtatcc agttcggaag ttttttgcct ttagaccaat atgattctcc 1206241 ttatatttta gtatatgaag aagaccgaaa agaatgggat aaacgtgaaa aaacaggctc 1206301 ggaaaaaacc gtgatcctgc cgaaaatgta cgggccatgg aaagaagaaa cagaggaaga 1206361 cggctattac acaaacgacg tggctgacga gttgctgaga ttcctgttag aaccaagccg 1206421 tcatagcaaa gatcagcttt ttgaattgca agtcacagag aaaacctcaa aagaagaagc 1206481 aaaaacaaaa attatcgagt ggaaaagaca attttcatca attttcgaca aatattaaga 1206541 aaaaccttcc atgtttcgag ttttctagat acaataaacg tataaaaata atacatgtta 1206601 tagcttgtca aaaggagttg aacatgactt gatcacaagg cttgtcatga tcttttctgt 1206661 cctcctttta ttgagtggat gtggacaaac tccgttcaaa ggaaaaattg agaaggtcgg 1206721 catgctcttt cctgatacga ttaatgacct cgtatggggc acaaaagggt ataaaggatt 1206781 actgaatata caatccaaat acaatgtgga cgtctattat aaagaaggcg ttaaaacaga 1206841 agaagatatc ataaatgcga ttgaggattt tcataagagg ggcgtcaatc tgctctacgg 1206901 ccatgggagt gaatatgctg aggtgtttaa cttggtcggc gaagattatc cagatatgga 1206961 attcgtcatt tccaatgcga aagcgaaagc tgataatgta acaagtgtcc attttagcgg 1207021 ggaagcaatg ggcttttttg gaggaatgac tgctgcccat atgtcgaaaa cgaatcaggt 1207081 cggtgtaatt gcttccttta cgtggcagcc tgaggttgac ggttttatca aaggggccaa 1207141 gtatgaaaat ccggatatag aggtaaatac gaaatatacg gatcattggg atgatgatac 1207201 aacagcagta aagctttatc agaaaatgaa gaacgaaggc gcggatgttg tgtatcccgc 1207261 cggagacggg tataatgttc ctgttattca gcaaatcaaa aaagacggtc tttatgccat 1207321 aggctacgtc acagatcaat cggatctggg cgagaatacc gtattaacca gcacggtgca 1207381 aaatgtggac aaggcctatg aaatcattgc tgaacaattt aataaaggca cccttgaggg 1207441 cggcgatcat tactacgacc tgaacacggg agtcgttgag atgggaacat tcagcccgct 1207501 cgtcgatcaa gactttcagc aaagaatcgc caagctgatc aaaacataca acaaaacagg 1207561 cgagctgcca aaaaacgagt aatggagtga cgtcacatgc agcacgaaaa atcacttgaa 1207621 ttcttgcaaa ttgccatgaa atatctccct gaagcgaaag aacagcttga gaaatcaggc 1207681 attgagctct caatggaggc catccagccg tttatgaatc tatttacaac ggtaatggcg 1207741 gaagcttatg agcttggcaa gtctgacgct aaatctgaaa cagaataaga agaagccact 1207801 tttttgaaag tggcttttca catgattttc tttttaatag cggagagcat gggcgcaagc 1207861 tcctttaaag cgggcttgat ttgatcaaga gagttcataa ttgaaccgat ttggtccata 1207921 atatgcatgt aattaatcgt ctcttcgtcg tttgtctgag aaacctgaga aacttcctct 1207981 tgctgttcct cctccttctc ttctgttggt tttgctgcat cgccgaacat cattcttgaa 1208041 aacacatcca actgcatacg cctcctttcc atataccata ctctatgagt aagatgaact 1208101 gatagtttag acgaatatat tgccatgtga aaaaaaatag gatagaatta gtacctgata 1208161 ctaataattg atcacaacct gattgatctt ctaaatttaa gatataaagg agtcttccct 1208221 aatgaaagct ggaatacttg gtgttggacg ttacattcct gagaaggttt taacaaatca 1208281 tgatcttgaa aaaatggttg aaacttctga cgagtggatt cgtacaagaa caggaataga 1208341 agaaagaaga atcgcagcag atgatgtgtt ttcatcacat atggctgttg cagcagcgaa 1208401 aaatgcgctg gaacaagctg aagtggctgc tgaggatctg gatatgatct tggttgcaac 1208461 tgttacacct gatcagtcat tccctacggt ctcttgtatg attcaagaac aactcggcgc 1208521 gaagaaagcg tgtgctatgg atatcagcgc ggcttgtgcg ggcttcatgt acggggttgt 1208581 aaccggtaaa caatttattg aatccggaac ctacaagcat gttctagttg ttggtgtaga 1208641 gaagctctca agcattaccg actgggaaga ccgcaataca gccgttctgt ttggagacgg 1208701 agcaggcgct gcggtagtcg ggccagtcag tgatgacaga ggaatccttt catttgaact 1208761 aggagccgac ggcacaggcg gtcagcactt gtatctgaat gaaaaacgac atacaatcat 1208821 gaatggacga gaagttttca aatttgcagt ccgccaaatg ggagaatcat gcgtaaatgt 1208881 cattgaaaaa gccggacttt caaaagagga tgtcgacttt ttgattccgc atcaggcgaa 1208941 catccgtatc atggaagctg ctcgcgagcg tttagagctt cctgtcgaaa agatgtctaa 1209001 aactgttcat aaatatggaa atacttctgc cgcatccatt ccgatctctc ttgtagaaga 1209061 attggaagcc ggtaaaatca aagacggcga tgtggtcgtt atggtagggt tcggcggagg 1209121 actaacatgg ggcgccattg caatccgctg gggccgataa aaaaaggtga ggtgcacaca 1209181 agatgactaa aaaaagagta gttgttacag gacttggagc attatctcca cttggcaacg 1209241 acgtcgatac aagttggaat aacgcaatca acggtgtgtc cggaatcggt ccgatcactc 1209301 gtgttgacgc tgaagaatat ccggcaaaag ttgccgctga attaaaagat tttaatgttg 1209361 aagattatat ggataaaaaa gaagccagaa aaatggaccg ctttacacaa tatgcggttg 1209421 tggctgcgaa aatggcggtt gaagatgcag atcttaacat taccgatgag atcgcgccga 1209481 gagtcggtgt ttgggtaggc tccggtatcg gaggacttga aacactagag tctcaatttg 1209541 aaatcttctt aacaaaaggc ccaagacggg taagcccgtt tttcgtgcca atgatgattc 1209601 ctgacatggc gacaggccag atttctattg cattaggagc aaaaggggtg aactcttgta 1209661 cggttacagc atgtgctaca ggaacgaact ccatcggtga cgcgtttaag gttattcagc 1209721 gcggtgatgc agacgtgatg gtcacaggcg gaacagaagc gccgctgaca agaatgtcat 1209781 tcgccggctt tagtgccaac aaagcgctgt ctactaatcc agatccgaaa acagcgagcc 1209841 gcccgtttga taaaaaccgt gatggctttg tcatggggga aggtgcaggg attatcgttc 1209901 ttgaagaact tgagcatgcc ctggcccgcg gcgctaaaat ttacggagaa attgtcggct 1209961 acggctcaac cggagacgct tatcatatca cagcgccggc ccaagacggt gaaggcggag 1210021 cgagagcgat gcaagaagcc attaaagatg caggcattgc acctgaagaa attgattaca 1210081 tcaatgctca cgggacaagc acgtattaca acgacaaata cgaaacaatg gcgattaaga 1210141 ccgtttttgg cgagcatgcg cataaacttg cggtaagctc tacaaaatcg atgacaggcc 1210201 acctcttagg agcagccggc ggtattgaag ccattttctc tatcctggcc attaaagaag 1210261 gcgtgattcc gccgacaatc aatattcaaa cacctgacga agaatgtgat ttggattatg 1210321 tgcctgatga agcccgcaga caggaactta attatgttct cagcaactca ttaggattcg 1210381 gcggacacaa cgcaacatta atctttaaaa aatatcaatc ataatcaagc caaaccggct 1210441 gcccttaaag ggtagccggt tttttttgtg tgcataggat taaaagagga ggcgatcaca 1210501 tgagtgtaga acaaacatat agctggctca ggaaggccgg ttcaatagat gatttggcgc 1210561 attacattat cccgcttttt tcaggtgcgg agaaaaagaa ctggaagggc attctggggc 1210621 atcttcagca tcatgggatg tttaaaaaca taaaagaggg tattcagacg gtttccaagc 1210681 tgaaggaaaa aggtttttac ggacatatcc aaaaggaaga acagtacctc aaaaacaaat 1210741 ggcaaggtcc tgatgtacca attgttacgc tgccggttga tgaacgaaac aggagaatcc 1210801 gtttagaatt cggatcaaaa tcaggactcg cctttcaaga caaaatgttc ctttttcttt 1210861 cgtcagattt agattttggg tcggtatctg cccttatgac gcatgagtat catcacgttt 1210921 gccggttagg tcatctgaca aaagaggaaa aggatgtcac attacttgat acaatcatca 1210981 tggaagggct ggcggaatat gctgtttatg agaggttcgg ccgaagtcaa acggctgaat 1211041 ggacgacttg gtatacaccg gaacagcttc aggctttata tgaaaaaaag attgcgcccc 1211101 atcgggatat caaacgggat aatcgattat ttccccagct gttattcggc aaaggatatc 1211161 agccaaaaat gcttggatac gcagttggat tcaatattgt aaaaaaatat ttaaccgcca 1211221 gcaaggcaag caccgcagac gggctgtcca ttcctgctga gacctttttg gatgcaatgc 1211281 tttaaaagga taaaataatg gaatttcatt aataatatta catttatcct aaaaaattct 1211341 tgattttgca aaatgattgt aataatatac aactataaaa tttttcgata attcaatatt 1211401 atttattatt tctgaataaa gggattgctt tctcttgaaa acgtttgaca acaagagggg 1211461 ggaaagggga gctagcatga gcacactttt agaagtgaat aatttaaaga cttatttttt 1211521 caggaaaaag gagccgatcc ctgcggttga cggagtcgat tttcacatca gcaaaggcga 1211581 aaccgtcgcg cttgtaggtg aatcgggctc cggaaaaagc attacttctt tatcaattat 1211641 gggcctcgtc caaagctcag gcggaaaaat catggacggc tctattaaac tcgaagacaa 1211701 agacctcacc tcattcactg aaaacgatta ttgcaaaatc cgcggtaacg aagtatccat 1211761 gatctttcag gaaccaatga cctcccttaa tccggtgtta acaatcggag aacaaattac 1211821 cgaagtgctg atttaccata aaaacatgaa gaaaaaagaa gcccgtcaac gagctgttga 1211881 actcttgcag atggtcggtt tctcccgggc ggagcaaatt atgaaggagt acccgcatcg 1211941 gctgtccggc ggtatgagac agagggtgat gattgccatc gcactgagct gtaatcctaa 1212001 actgctcatt gctgatgaac caacgacagc gctggacgtg acaatacaag cccaggtgct 1212061 ggagctcatg aaagatctct gtcagaagtt caatacatcg attcttctca tcacacacga 1212121 cttaggtgtc gtgtctgaag ctgccgatag agtgattgtc atgtactgcg gacaagtcgt 1212181 agaaaacgcc actgttgatg acttattttt agaaccgctt catccgtata cagaaggcct 1212241 gcttacgtca attcctgtta tagatggaga gattgataaa ttaaatgcga ttaaaggcag 1212301 tgtgcctaca ccggataatc tgccgccggg gtgccgtttt gccccaaggt gcccgaaagc 1212361 tatggataag tgctggacaa atcagccttc gcttttgaca cacaaaagcg gaagaacggt 1212421 gagatgcttt ttatatgagg aagagggtgc cgaacaatca tgacagcagc taatcaagaa 1212481 acaatcttag agcttcgtga cgtaaaaaaa tactttccga tccggtcagg cctttttcaa 1212541 agaaaagtcg gtgatgtaaa agcggtggat ggtgtttcat tttcgttaaa aaaaggagaa 1212601 acactcggaa tcgttggaga gtcgggctgc ggaaaatcga ctgccggcag aacgatgatc 1212661 agactgtaca aaccgacaga gggccaaatt ctttttaaag ggcaggatat ttccaatctg 1212721 tcagaggaga agctgcggaa gagtgtccgc aaaaatattc aaatggtttt ccaagatcca 1212781 tttgcttcgt taaacccgag aaagaccctg cgttccatca taaaggagcc gtttaatacg 1212841 cacaacatgt ataccatgcg tgaacgaaac gaaaaagttg aagagctgct tgcaagagta 1212901 gggcttcacc cgtcgtttgc cggccgttat ccccatgagt tttcaggcgg ccagcgtcag 1212961 cggatcggca ttgccagagc actcactttg aatccagagc tgatcattgc agatgagccg 1213021 gtttccgcac ttgatgtatc cattcaggcc caagtgatta acttgatgga ggaattacag 1213081 gaagaattta atcttacgta tctatttatc tctcatgatc tgagtgtcgt ccgccatatc 1213141 agcgacagag tcggagtaat gtatcttggc aaaatgatgg aactgaccgg caagcatgag 1213201 ctttatgaca acccgcttca cccatatacc caagcgcttt tatcctccgt tccggttaca 1213261 agaaaaagag gttctgtcaa acgtgaacgc attgtcctga agggagaact gcctagtccg 1213321 gccaacccgc caaaaggctg cgtattccac acaagatgtc ctgttgcaaa accgatatgc 1213381 aaggaacaaa taccagaatt taaagaagct gctcccagcc actttgtggc ttgtcacctt 1213441 tatagctaat gttgcccgca cagctttgag agggggtatg cacactacat aaacaacagc 1213501 ctagaagaac gaacatttca agagggggaa tatctaatga aaagacggaa aaccgcactg 1213561 atgatgctaa gtgtattgat ggttctggcc atctttttat cagcctgctc gggatcaaaa 1213621 tcaagcaaca gcagcgcgaa aaaatcagca ggcaaaccgc agcaaggcgg ggatttggtt 1213681 gttggttcaa tcggagaacc cacacttttt aactctctgt attctaccga tgacgcaagt 1213741 acggatattg aaaatatgct gtacagcttt ttaacgaaaa cggatgaaaa actaaatgtg 1213801 aaattgtcac tcgctgaaag cattaaagaa ttagacggcg gccttgcata tgatgtgaaa 1213861 attaaaaaag gcgttaagtt tcatgacgga aaagaactga ctgcagacga cgtcgtattt 1213921 acgtacagtg tccctttaag caaagattac aagggagaac gcggttcaac atatgaaatg 1213981 ctgaaatccg tagaaaaaaa ggcgattacg aagtcttgtt taagctgaaa tataaagacg 1214041 gtaatttcta caacaatgcg ttagacagca cagctattct gccgaaacat attctcggta 1214101 atgttccgat tgctgattta gaagaaaatg agtttaacag aaagaaacca atcggttcag 1214161 gaccatttaa gtttaaggaa tggaagcagg gccaatatat taagctcgaa gcgaatgatg 1214221 attactttga aggaagaccg tatttagata ctgtgacgta taaagtcatt cctgacgcaa 1214281 atgctgccgt tgctcagctg caggcaggcg atattaattt ctttaatgtg cccgccactg 1214341 actacaaaac ggctgaaaaa ttcaacaacc taaaaatcgt tactgatttg gcattaagtt 1214401 atgtgtacat cgggtggaat gaaaaaaatg aattattcaa ggataaaaag gttcgtcaag 1214461 cgctaacaac cgctcttgac cgcgagtcaa tcgtcagcca agtattagat ggagacggcg 1214521 aggtagctta cattccggaa agccctttat cttggaacta tcctaaagat atagatgttc 1214581 cgaaatttga gtacaacgag aaaaaagcga aacagatgct tgcagaagcc ggctggaaag 1214641 atacgaacgg tgacggcatt ctggataaag acggaaagaa attctcgttt acccttaaaa 1214701 cgaaccaagg aaacaaagtc cgtgaagaca tcgctgtcgt cgttcaggaa cagctgaaaa 1214761 aaatcggcat tgaagtgaaa acccagatcg ttgaatggag cgctctcgtt gaacaaatga 1214821 atcctccgaa ttgggatttt gatgcaatgg tcatgggatg gagtttatcc acattcccgg 1214881 atcaatatga tattttccat tcaagccaga ttaaaaaggg tttgaactac gtttggtata 1214941 aaaatgccga agcggataaa ctcatgaaag atgcaaaatc aatcagtgac agaaagcagt 1215001 attcaaaaga atatgagcaa atctatcaaa aaattgcgga agatcagccg tatacgttct 1215061 tgtattatcc taacaaccat atggcaatgc cggaaaatct tgaaggatac aaatatcatc 1215121 cgaaacgtga tttgtataat attgaaaaat ggtggcttgc aaaataaatt tcccttaaag 1215181 gggagggaga gcgttttctc cctcttctgt ttttaataag gaaagtaaag ggggacaagt 1215241 atatggctgc atatattatc agaagaacct taatgtctat cccgatttta ttgggaatta 1215301 cgattttatc atttgttatc atgaaagccg cgcccggaga tccgatgaca ttaatgatgg 1215361 acccgaaaat cagccaggct gacagagagc agtttattga aaaatacggt ctgaatgatc 1215421 ctcagtacgt tcaatattta aagtggctag gcaacatggt gcagggtgat ttcggaacgt 1215481 ctattgtcag aaaaggaacg cctgtttcag aattgattat ggcaagacta cccaatacgc 1215541 tcctgctgat gctggtttca acgattttgg ctcttatgat ttctattccg ttcggtgtcc 1215601 tgtcggcaaa gcggccgtat tcaaaaatcg actatggcat tacatttacc tcgtttatag 1215661 gcctggctat tccaaacttt tggtttggat taattttgat tatggtgtta tcggtaaatc 1215721 tcggctggtt tccaactggg ggtgtcgaga cactgaatac cgaattcaat atatttgacc 1215781 ggattcatca tttaattctg cctgcattcg ttctagctac agctgacatg gccggactga 1215841 cgagatacac gagatccaat atgcttgatg tattaaatca agattatatt cgcacagcga 1215901 gagcaaaagg atttaaagag aacagagtgc tatttaaaca tggattgagg aatgcattat 1215961 tacccgtcat tacaattttc ggtttgatga ttccttcatt tatcggcgga tctgtcgttg 1216021 tcgaacaaat tttcacttgg ccgggattag gaaagctgtt tgtcgattca gcattccagc 1216081 gcgattatcc ggttatcatg gcaatgactg tgatctcggc ggttcttgtc gttgtcggaa 1216141 acctcattgc agacatcctt tacgcgattg ttgatccgcg gatcgaatat taaaaggagg 1216201 gaaacagaga tgtcagagct gcaaacaact ccctcgccgg agatcaggct gaaagaaaat 1216261 atttcgaaaa agccagaaac aatgacaaag attttctggg aaaaattctc gaaaaacaaa 1216321 ctggccattt taggtgccgt tattcttttt atcattatta tgtctgctgt tttcgcccct 1216381 ttaattgcac cttatcccca agagcagcaa agcctgcttg ataaatataa ggcgccgggc 1216441 cttgaacatc tgatgggaac ggataaattt ggacgtgata ttttcagccg gatcctatat 1216501 ggagcgcgtg tctctttatt ggttggattt gcgtccgtag tcggttcgat tttgatcgga 1216561 acggttttag gagcattagc cggatatttc agaggaatag tggatgctgt cattatgcgt 1216621 gtagttgaca ttgtgttatc cattcctgat attttcttgt tgatcacgct ggtcaccatc 1216681 ttcaagccgg gtgtggacaa attgatttta attttctgtc tcacaggatg gaccacaaca 1216741 gcacgattag taaggggaga attcttgtcg ctccgttcaa gggaatatgt tcttgctgct 1216801 aaaacaattg gaacaaaaac gcacaaaatt attttttctc atatcctgcc caatgcgtta 1216861 gggccgatta tcgtgtcagc tacgctgaaa gttgggtctg ttattctagc tgaatcggcg 1216921 ctaagctact tgggctttgg aatccagccg ccaatcgcta gctgggggaa catgcttcaa 1216981 gacgcacaga atttcacagt aatgattcaa gcatggtggt acccgttatt tcccgggcta 1217041 tttattttaa tgaccgtttt atgcttcaac tttgtcggtg atggcctgcg ggatgcgctt 1217101 gacccgaaaa atattaaata aaaatgaata tcatatctgt tataaaatat caccaaatca 1217161 gaaaaaagca ggtctccttt agtcagaaaa tatacaaaga gatctgcttt ttatgattct 1217221 tacataaacc cagtgattcc agatttcctc aatctctttg gaataatttc tctatccctt 1217281 gcctatactg tggacaacag tttttataaa agtgaggggt tagagatgtt atttcttcat 1217341 gatgtgtggg tcaattggtt tgaaggggaa gaaaatggct acaatgtatg ccactttcac 1217401 gaatggcgca aggaagatac ggttgagctt ttggatcagg tgccgctgtt aagggtgccg 1217461 tcagtactgt ttcattacat agaaaacgat ttgtcagagc ttccgaaagg tttgcttgaa 1217521 gacgtacatc agaaatcgta cattcgaaaa aatcatgagc ggacaaagct tgagtattgt 1217581 tttgtcgtaa cagacggaat cggcatttta gctgttgaca cgatcggcta cacgatccct 1217641 gtcagaaaaa gccgtctaat cccaagacag gagcagctcg tttatgaaat ggtaaaagat 1217701 gtagagcctg aaacatatga atttgagcca aagaagctgg aatcctccaa ggaatatcac 1217761 atcttatcat tagcaccaga acatgtcaga ggactgacaa gaaaagaacg gcaaattaag 1217821 cagctgatgt ttatggcgct tgaccaatta aaagggctga aaaaccgagc ggaaattggc 1217881 tactggtaca cagagtggaa tccgcatatg tatgaacaaa tcaaaaggat gagctttgaa 1217941 gagatttggg acatgctgta taacgaaaca attgaaggct ggtcggacaa acacctagct 1218001 ttttgcgaaa acctaataaa aggacagcct tttttcgaaa agctttggga aatggaaaac 1218061 gaatcaaagg tcaactgaaa aaaaccgctc tttgcaaaga gcggtttttt gattagcgtc 1218121 tttttcttcc aagacccatg gcattctcca tttttttcag cattttgttt gctgtccgat 1218181 tcgctcgttc cgcgccttca tcaagaatcc ggtctaattc ttcagattct atcagctcgt 1218241 aatagcggtc ctggatcggt tttaatgcgt tcactacgac ttctgccaaa tcacctttaa 1218301 actcgccgta gccttttcct tcgtactttg cttcaagctc ttcaattgtc gtattgccga 1218361 ggattgaata aattgtaaga aggttggaaa cgcccggttt gttttcctta tcaaatttga 1218421 caatgccttc agaatccgtt actgcgcttt tgattttctt ttcaagctgc ttcggctcat 1218481 ccagcaatgt aatataagct ttctgattcg gatcagattt gctcattttc ttcagcggat 1218541 cattcagaga catgatacgt gcaccgactt ttggaatttt cacttccgga atcgtaaaga 1218601 tgtcgttgta ttttttgttg aagcgttctg caagattccg cgtcagctca aggtgctgct 1218661 tttgatcctc gccgacaggt acaagatccg ttccgtacag cagaatatca gcggccatca 1218721 gcggcggata tgttaacagg ccggagacga cagcttcatt gcctttggat ttgtccttaa 1218781 attgagtcat ccgctcaagc tcgccgatat aggcgacaca ctgcatcatc catccggcct 1218841 gcgcatgtgc ggggacctct gactgaataa acaatgttgc tttttctgga tcaagtccga 1218901 cagctaagta aagcgccgcg agattgcgga tattctttct aagctcaagc cggtcttgag 1218961 gaacagttat cgcatgctga tcgacgatgc aaaaatagct gttataatca tgctgcagtt 1219021 cgacaaactg cttcattgca ccgatatagt tgccgagcgt cactgagccg cttggctgaa 1219081 tgcctgaaaa aatcgtttgt ttcatgaaaa catcaacctc atttcttaaa acataataaa 1219141 aaaggctcat tcttcccctg taaaaaaggg acgaatgaac cgtggtacca ccctgattat 1219201 tccattaaaa tggaatcact ctgacgtttg taacggagac tgctccggct gagcctactt 1219261 ttttccagtt cggtcagctg ctccaaagtc cattccacat tgcccgttat ctgctcccag 1219321 caccgcagac tctcttcaaa caggtgaaac gtgtactact ctttttcata gcaagctttt 1219381 cttttgattg cttcattata aatcaattat aaccaattgt catcatgaaa aaacattctt 1219441 ttttccagta aaattgtaat aatataaata acacgagtgc tgtaaaatcc ttaaatgata 1219501 actgctatca gcgtaaaaac aggcagatat tatatgtaaa aagcaatatg ggcagaaaac 1219561 acatgaaaaa gtttttaatc aatttatgct ttaaatggta gaaggatatt atgttcatgg 1219621 aagaaaaact aacgaagttt aaatatttta aattgataaa ataatattgc aataaattat 1219681 ttgtttcatt ataatgaact tgttcactct attgttacag cttttttaca aaaataatca 1219741 gaaaagacgg aacagaataa aagttgtgga aactcaggtt catttgtctg atatttctga 1219801 ggatttagcc gtaaggagct gaaaattatt attagggggt ttgcgaatat gaaaaaacgt 1219861 tggtcgattg tcacgttgat gctcattttc actctcgtgc tgagcgcgtg cggctttggc 1219921 ggcagcggat caaacggtga agggaaaaag gacagtaaag gaaagacgac acttaacatt 1219981 aatattaaaa ctgagccgtt ctccttacat ccgggattgg caaatgattc agtatcaggc 1220041 ggtgttatcc gtcagacttt tgaaggattg acacgtatca atgcagatgg tgagcctgaa 1220101 gaaggcatgg cttctaaaat tgaaacgagc aaggacggaa agacatatac atttaccatt 1220161 cgtgatggtg tgaaatggtc taatggagac cctgtaactg cacaagattt tgaatatgct 1220221 tggaaatggg cgcttgaccc taataatgaa tcacaatacg cttaccagct ctactacata 1220281 aaaggtgctg aagcggcgaa taccggaaaa ggcagcctag acgatgtggc agtaaaagct 1220341 gtgaatgaca aaacgctgaa ggttgaatta aataacccga ctccatattt cactgaatta 1220401 actgcgttct atacgtatat gccgatcaat aagaaaattg cagagaaaaa taaaaagtgg 1220461 aatacaaatg ccggagatga ttatgtatca aacgggccgt tcaaaatgac ggcatggaaa 1220521 cacagcggct ctattactct cgaaaaaaat gaccagtatt gggataaaga caaagtcaaa 1220581 ctgaagaaaa tcgatatggt tatgatcaac aataacaata cggaactaaa aaaattccaa 1220641 gctggcgaac ttgattgggc cggtatgccg ctcggacagc ttccgacaga atccctgccg 1220701 accctgaaaa aagacggttc tttacatgtt gagccgattg caggagtgta ttggtacaaa 1220761 ttcaacactg aagctaagcc attagacaac gtcaatatcc gtaaagcttt aacatattcg 1220821 cttgaccgtc agtcgattgt taaaaacgtt acgcaaggag agcaaatccc ggcaatggct 1220881 gcagtgccgc ctacaatgaa gggatttgag gataacaaag aaggatactt caaagacaat 1220941 gatgtcaaaa cagcaaaaga ataccttgaa aaaggcctaa aagaaatggg cttaagcaag 1221001 gcatctgatt tgccaaaaat caaattgtct tacaacactg atgacgcaca cgcgaaaatc 1221061 gctcaagcag tacaagaaat gtggaagaaa aatttaggcg ttgatgttga gcttgataac 1221121 tcagagtgga atgtctatat tgataagctc cacagccaag attatcaaat cggccgtatg 1221181 ggctggctcg gcgacttcaa tgatcctatc aacttccttg aattgttccg cgacaaaaac 1221241 ggaggaaata acgatacagg ctgggaaaat ccagaattca aaaagcttct gaatcagtca 1221301 caaactgaaa cagataaaac aaaacgtgca gagctgctga aaaaagcaga aggtattttc 1221361 attgatgaaa tgccggttgc cccaatctat ttctatactg atacttgggt acaggatgaa 1221421 aacctaaaag gtgttatcat gccaggtact ggtgaggttt atttcagaaa cgcatatttt 1221481 aaataaggct acgtctgaaa ataaaagacc tcaaggtata tggggagaaa agccccatat 1221541 acctttctta ctgatggagt ataaaaatgt aaaaaccatg gaggtgttcc cccttgctaa 1221601 aatatatcgg aagacgctta gtctatatga ttatcacact atttgtgatt gtaactgtga 1221661 cattcttctt aatgcaagca gcaccgggcg ggccattttc aggtgagaaa aagcttccgc 1221721 ctgaaattga agcaaattta aatgcgcatt atggcttgga caagccgctg tttgtacaat 1221781 atgtcagtta tttgaaatca gttgcaatgt gggatttcgg accgtcattt aaatataaag 1221841 gtcagagtgt taacgacctg atcagttcag gtttccccgt ttcatttact cttggagcag 1221901 aagctattct cctcgcttta gcgttaggtg tattgtttgg ggtcattgca gccctttacc 1221961 ataataagtg gcaggattat accgtcgcga ttttaacgat atttggtatt tcggttccga 1222021 gctttatcat ggcggctgtt ctgcaatatg tgttctccat gaagcttggg ctgtttccgg 1222081 tcgcggggtg ggattcctgg gcatacacct ttttgccttc catcgcactt gcttccatgc 1222141 cgatggcgtt tattgccaga ctttcccgtt caagcatgat cgaagtgtta aacagtgatt 1222201 atatccgcac agcgaaagcg aaagggcttt cccgcccagc ggttacagtg cggcacgcca 1222261 ttcgaaacgc acttttgccg gttgttacat atatgggccc gatggccgca caggtcttaa 1222321 cggggagctt cattattgaa accatttttg ggattccggg gcttggtgca cacttcgtca 1222381 acagtattac aaaccgtgat tatacggtca ttatgggtgt aacggtgttc ttcagtgtca 1222441 tcttgctatt gtgtgtatta atcgtagatg tgttatacgg cattattgat ccaagaatca 1222501 agctttccaa agcaaagaaa ggagcctagg ccatgcagaa cattccaaaa aacatgtttg 1222561 aaccagccgc agcgaatgcc ggcgatgcag aaaaaataag taaaaagagc ctttccctct 1222621 ggaaagatgc gatgcttcgc ttccgcagca ataagcttgc aatggtcggg cttatcatta 1222681 tcgtacttat tatccttatg gcaatttttg cgccgatgtt ctcaaggtat gattattcaa 1222741 ctactaatct cttaaatgcg gataagccgc cttcaaaaga tcactggttc ggaacagatg 1222801 atcttggacg ggacattttc gtccgtacat gggtaggggc gcgaatctca atctttatcg 1222861 gtgttgcagc tgctgttctc gatttgctga tcggcgtcat ttgggggagc atttcaggct 1222921 tccgcggagg aagaacagat gaaatcatga tgcgtatcgc tgatatcctt tgggcagttc 1222981 cttcattatt aatggttatc ttactgatgg ttgttcttcc gaaaggtcta tttacgatta 1223041 ttattgccat gacgattaca ggctggatta atatggccag aatcgtgcgc ggacaagtgc 1223101 tgcagctgaa gaatcaggag tatgtgcttg cttcacagac actgggtgca aaaacatccc 1223161 gtcttctatt taaacatatc gtgccaaacg caatgggttc tattttggtc acgatgacac 1223221 tgacagttcc tactgcgatt tttacagaag cctttttaag ctatttggga cttggtgttc 1223281 cggctccgct ggcaagctgg ggaacgatgg cttctgacgg attgcctgca ttgacctatt 1223341 atccgtggcg tttattcttc cctgccggat ttatctgcat tacaatgttt ggttttaacg 1223401 ttgtcggcga cggattaaga gacgcattgg atcctaagtt acgtaaataa gggagtgata 1223461 cgggtgacac gcctattaga agtaaaagat ttagcaattt catttaaaac atatggcgga 1223521 gaggtccagg cgatccgcgg agtgaatttc catctggata aaggggagac gctggccatt 1223581 gttggagaat caggttccgg aaaaagtgta acctctcaag cgattatgaa gctgattcca 1223641 atgcctccgg gttatttcaa acgcggtgag atcctgtttg aaggaaagga tctggtgccg 1223701 ctgtccgaaa aagaaatgca aaatgtccgg ggaaaagaga tcggcatgat attccaagat 1223761 ccgatgacct ctttaaatcc aacgatgaag gtcggtaaac aaattacgga agtgcttttt 1223821 aaacacgaaa agatctcgaa ggaagcggct aaaaaacgcg cggttgaact gctggaatta 1223881 gtcggtatcc caatgccgga aaagcgggtg aaccaatttc cgcatgaatt ttcaggcggg 1223941 atgagacaga gggttgtcat tgccatggcg cttgcagcga atccgaaact tctgatcgcc 1224001 gatgagccga caactgctct tgatgtaacg attcaagcgc aaattttgga attaatgaag 1224061 gatttgcaaa agaaaattga cacgtccatc atctttatca cacacgatct tggtgttgtg 1224121 gctaacgttg ctgaccgggt cgctgtcatg tacgcgggac agattgtaga aactggtacg 1224181 gtagacgaaa tcttctacga cccgagacat ccgtacactt gggggcttct tgcatccatg 1224241 ccgacactgg aaagttcagg agaggaagag ctgactgcaa ttccgggcac gccgcctgat 1224301 ttgacaaacc cgccaaaagg agatgctttt gccctgcgga gctcttacgc gatgaaaatc 1224361 gattttgaac aggagccgcc aatgtttaag gtatccgata ctcattatgt aaaatcgtgg 1224421 ctgcttcatc ctgacgcgcc aaaggtagag ccgcctgaag cggtaaaagc gaaaatgcgt 1224481 aaactggcaa acacgtttga aaaacctgtc ttagtgagag aagttgaatg aattgactga 1224541 aaaactatta gaaatcaaac atttaaaaca gcactttgtc acgccgaggg gaacggttaa 1224601 ggctgtagat gatttatcat ttgatatcta taaaggtgaa acattagggc tggttggtga 1224661 atctggctgc ggtaaatcga caacaggccg aagcattatc aggctgtacg aagcaaccga 1224721 tggtgaggtg ctgttcaacg gcgaaaatgt gcacgggaga aaatcgcgga aaaagctgct 1224781 ggaattcaac cgcaaaatgc agatgatttt ccaagacccc tatgcatccc tgaatccgag 1224841 aatgacagtt gctgatatta ttgctgaagg ccttgatatt cataagctgg caaaaacgaa 1224901 aaaagagcgg atgcagcgag ttcatgaact attggaaaca gtgggattga acaaggaaca 1224961 cgcgaaccgc tatcctcatg aattttccgg cggccagcgc caaagaatcg ggattgccag 1225021 agcgcttgct gttgatccgg aattcattat cgcggatgag ccgatttccg ctttggatgt 1225081 atccattcaa gcgcaggtcg tgaatttaat gaaagaactg caaaaagaaa aagggctcac 1225141 atacctgttt attgcccacg atttatcgat ggtcaaatac atcagtgacc gcattggcgt 1225201 catgtatttc gggaaactgg ttgagcttgc gccggcagat gagctttatg aaaatccgct 1225261 tcacccatat acaaaatcat tgctttctgc gattccgctt cctgatccgg actatgagag 1225321 aaatcgcgtt cgccagaaat atgatccgtc tgtccatcaa ttaaaggatg gggaaacgat 1225381 ggaattccgt gaagtcaaac cgggacattt tgtgatgtgc acggaagccg aatttaaagc 1225441 tttttcatga ttcatcaatc cttcaagaga tttctcttga aggatttttt tgcgtcttca 1225501 tagaaagtga gaatgataac atttacaatt agaggaaaaa gcggaggcga aatacgattc 1225561 aatttctgca taacaaaaat gtttttgcgc tattgctgtc tcaatctttt caatctttag 1225621 caggagtcct cgtcacaatc gttttaatgg tccggatcta tcaaatgact gactccgttt 1225681 ttttggcggg ccttatttta tcgttcatgt cgtttgcgag tatagcagca agcttttgcg 1225741 tctctccggt gcttcgcatt ctcggtttta aaaaggtgct tgcgggagcg aatctgctga 1225801 gagcggtctt tattatactg atggcataca gcgtcactca tcacggacag gcattctttt 1225861 ggattacgct gctgtttgtg ttttgttttt ccttcgcggg cgcttttttt cagccggcaa 1225921 gatttgcgct gctgccgatt attgttccaa agaagcaata tgtaaaagcg aatggtgtga 1225981 tctccctctc gaatcaattg ttcttaacag caggctgggg ccttggaggc cttctgacgt 1226041 acgccgtccc ttttgaactc gttgtcggcg ctgccatttg cctgtttgtt ctatcgggag 1226101 cttccatcag tgtgctgcat gtaaatgaag aagaggctgc aggaactgct gaaacagcat 1226161 ctgtcagaag tatatggaag gatttaatga tcatccctat tgtaagagac attactgtaa 1226221 tggacatgtt agaagctttg gcgggttccg tatggtcatc tgctattctc ctcgcattta 1226281 ctgcggctgt tttgcatgaa acagaggtgt ggtgggggat gtttaacgct tcctatttta 1226341 taggcgcaat tgtcggcagt gtgattgcta ttcgtttttc ttcttttttt gagcggaata 1226401 tgggctatgc cattatgttc agctcgcttg taatgtcggc gctgaccctt ttgttttcat 1226461 tttctccagt cccattttta tgcgctctgg cttgtgctgc aatggggcct ttttatcagg 1226521 tgcgtgatat ttgccaggaa accatgctgc aggaagttat tcccgagcag aaacgaatcg 1226581 gaatcatggc tgcaaaaaat gcgattttga ctccttggtc aggcgtcacc tactccatta 1226641 tggggctagt ggctgatgct gctggtgcga aaatagcttt tatcgcggct gctgcattat 1226701 atatcatgac atttctgatt gcactggcgc agccccgtct ggttcattac aggcgagaaa 1226761 atcgagttca atgagaaaca cttcaaaatg aacggagcag ctggctccgt tttgctgaaa 1226821 aaaaaatgaa accatggcgg aagttcgcac gtctttatag atgtaaggct gtttaaacaa 1226881 gaagaaatgg ggtatatcta aaagtatgaa gacaacgaac tcataaggag caaatcaatg 1226941 aactggtatg aaaagcttag cgagtacttt ccaattgaag aaatgaaatc aaaagcgcat 1227001 atggaagctc ttctgaaaga gcgaagcgat atttatcata aagatgaagg caaacatcat 1227061 attttaatgt ttgcggaatt cgattctttt atcttcgttg attatctgta tgtgtctaag 1227121 gatgcaagag ggcaggggct tggcggcaaa ttgatcgcga agctgaaaaa gaaaaataag 1227181 cccatattgc tcgaggtgga acctgtggat gaagatgata ctgatacaga aaaacgcctg 1227241 aggttttatc aaagagagca tttcaagcat gctcagtcaa ttgggtaccg gcgccggtca 1227301 ttggctacga atgaagtaaa caagatggag attctgtact ggtcaccaaa aacagaatca 1227361 gaagaagaaa ttcttgaagc catgaaacag acatatgaaa acattcatac ttataaagat 1227421 gagaaatggt acggagaatc gtacgaaaaa acggatgagg tcttggaaat catcgatgaa 1227481 gaaaaacaaa aaaatatttt cgatcagtta agctaattga gaataagaac atatcatgaa 1227541 cattaaaaat ttgctggatt gacacatttt tttcttagga tactgttcac acttactttt 1227601 ttatagtata atacctgtaa agattccttt tttagagtaa tttcaattta agaataaaat 1227661 agatgttcat cctactaatt agaggagtga agatgaatgg ttacactata cacatcacca 1227721 agctgtactt catgcagaaa ggcgagagcg tggctcgagg agcacgagat tccatttgta 1227781 gaaagaaaca ttttctctga acctttatca attgatgaaa taaaacaaat tcttcgaatg 1227841 actgaggacg gaacagatga aatcatctca acccgttcaa aagtattcca aaaactgaat 1227901 gtgaacgttg aatctatgcc gctgcaagat ttgtaccgct tgatcaacga gcatccaggt 1227961 ttgcttcgcc gtccgatcat cattgacgaa aaacgtttgc aggtcggata taacgaagac 1228021 gaaatcagac gtttcctgcc aagaaaagtt cgctctttcc aattaagaga agcacagcgt 1228081 ttggcaaact aatagatcgt atcatcaaaa gaaggctgag tcatcagcct tcttttattt 1228141 ttcaacctgc tggtaataaa tgctcgcaag gatgacaaac gcaaccgtca aaatggggag 1228201 gagcgtttcg actgtgccgt gctgcgccat aaaaagcgac agctttttgt ctctgacaat 1228261 catttctccg ccagtataag caagcagccc gcttcccgcg taaatcagaa gcggtatttt 1228321 ctctagtgca atatggatga gtttgctgcc ccaaataata accggaaccg atacacacaa 1228381 tcctataaca acgagagaaa actcaccgtg tgaagctccc gcaactgcga tgacgttgtc 1228441 cagcgacata aagagatctg caagcacaat cgttcgtatc gctctccaca gggaggtgct 1228501 gcttttaatg tgtttcgtgt cttttttttc aatcagcagc tgatatccta aatacagcag 1228561 gaaaattccg ccggcgcact gcaagaacgg aatgttcaaa agatatactg ctgcacttgt 1228621 taatccgatt ctcatggcaa cggcaataaa tgttccgaga ataatggctt gctgtctttg 1228681 cttgtccggc aaatgtctgc tggccatggc aataacaacc gcgttatctc cgccgaggat 1228741 caggtcaatc ccaacaatga cgagcagaga aatcagatag tcatgctcca tgaagcggca 1228801 cctcgctttc agtccttcgc ttgtactact actatatgag acaggtcata ttttatgata 1228861 tcagccgcct gatctgccgt tttttaggca aaggtgcatt tttatttctt ttgtgactgt 1228921 tttatcataa aatagaaata caaaggaatt cacactggcc ttggttaagg ttaagatgtg 1228981 gacggaatgg gtaaagtgta gtaaagtaca attaatcggg agcttagatg tcccttcaac 1229041 atcttatata gaagggaagg ttggcaaatg gaaattgaaa gaattaacga gcatacagta 1229101 aaattttata tgtcttacgg agatattgaa gatcgcggtt ttgacagaga agaaatttgg 1229161 tataaccgtg agcgcagtga agaacttttc tgggaagtca tggatgaagt tcatgaagaa 1229221 gaggaattcg ctgtggaagg cccactttgg attcaagttc aggcactgga caaaggatta 1229281 gaaatcatcg tcacaaaagc ccagctttcc aaagacggac aaaagctcga actgccgatt 1229341 cctgaggata aaaagcaaga accagcatct gaggatcttg acgccttgct ggatgatttc 1229401 cagaaagaag agcaagccgt caatcaggaa gagaaggagc aaaagcttca atttgtcttg 1229461 cgatttggcg attttgagga tgttatttct ctatctaaat tgaacgttaa cggaagcaaa 1229521 acgactttat attcgtttga gaaccgatat tatttatatg tagatttttg caatatgact 1229581 gatgaagagg ttgaaaatca gctaagcatc ctgctggagt acgcaactga atcctcaatc 1229641 agcatacacc gtcttgaaga gtacggcaag ctgattattt cagagcatgc tctagaaacg 1229701 ataaaaaaac actttgcatc atagcaaacc gatttccttc cggaaatcgg ttttttttat 1229761 gcacgaaaat gccattttag agatgtgaaa aatcaaaaac atatagacaa gcagaaaata 1229821 cagcgaacag gagttgatca tcttttccag aaagtatact tcatctggaa aggagagatg 1229881 acaattgttt agtgctgtga ctgaagacgg ccaaatgttt caccttctag gcgctcagca 1229941 aaaccagaaa ttaaagcgga gacggttctt ctgtccggta tgcgggggag agctagctgt 1230001 gaagctcgga cttcaaaaag cgccgcattt tgcccataaa cagaacaagt cctgcgccat 1230061 agacatcgag ccggaaagcg cctaccactt agaaggaaaa agacagctgt atgtatggct 1230121 gaaaacgcaa cgggcttcac caatattgga gccgtatata aggacaatca accaaagacc 1230181 ggacgtcatg gcaagaatca aggagcatat gcttgctgtt gaatatcaat gcgccactat 1230241 cgctccagat gtctttcaaa agcggacaga gggcttcaaa caagaaggaa tcatcccgca 1230301 gtggattatg ggatacagcc gcttaaaacg gactgcttcg tccttttatc agctttcaac 1230361 ttttcattgg cagtttatca atgcaagtcc atacagagaa ctgatatgtt attgtcctga 1230421 aaggcgttct tttctccggc tcagccacat cattccattc tacacaaacc attcttattc 1230481 ctcagtccaa acgatcccta tccatcgggc aggtgcaggc gatctttttt tcactgaacc 1230541 gaaaccctca attcaatatt caggctggac gaaagcgatt caccgttttc gccataaacc 1230601 ccatcggttt aactcaaagg aaacaaatcg ccttaggctg ctgttttatg agaaacgaca 1230661 gacgcctttt tcttttctgc cgactgaagt gtttgttcct gttagaaaag gggcagtttt 1230721 taagagtccg gtttttgtgt ggcaggggtt tctttatttg tttatgacgg atcttggagg 1230781 taaacgtgcg ccaattcgtt tttcagccgt tttgcagcag tgcaaactgc acattcataa 1230841 taagaacatt gcactcaggt ccgaatgcag cgaagagtgt ctttcagaag cggttaaaca 1230901 gtatattgat tttttgtgca agaagggatt tttaagggag actcagaaag aagtatatgt 1230961 gctgaatcag cctgcaggag gcatacactc catgcaggat ctcatagaaa gagaccgcag 1231021 ctgttttata gaatgagttt gtcttatttg gctcacccta agacaaaggt ggtgggcagg 1231081 ctgtgaaagg cacaaaagga aaggtttttc gtgtttttac tgcttttttg gcattcgttc 1231141 tcttcattac tgcatatgat ttgacaaaag gcagtgaaaa accggaagat attcacaaca 1231201 caagtttatt gagaaacagc tgttttttca attggcttga atcaaagaag acgaggggga 1231261 tcaccatggc tgaggaaaaa aaagcaaacc aactgcctga cagaagtgag gtaaaggcag 1231321 aagacacatg gagacttgag gatatttttc ctagtgatga ggcctggaat aaagaatttc 1231381 aagctgtaaa agaattaatt ccgaatttat ctaagtataa aggaaagctg gcagattcag 1231441 ctgatcattt atacgaggct cttacgtatc aagataaagt gatggagcgg ctaggtaggc 1231501 tgtacacata tgcgcatatg cgctctgacc aggatactgg gaactccttt taccaggggc 1231561 tgaatgacaa ggcgggaaac ctgtatacac aggccgcaag cgcgacagct tatttggttc 1231621 cggagatttt atccatagaa gaagacaaac tgcagcagtt cattcttgaa aaagaagaat 1231681 tgaagctgta ctctcatgcg attgaggaga ttacaaagga acgtccgcat gtgctgagcg 1231741 agaaggaaga ggcgctgctt gctgaagcct ccgaggtact ggggtcatct tcaaatacat 1231801 tcagcgtgtt aaataacgca gatataacgt ttccatccat taaagacgaa gatgggaatg 1231861 aaaaacagat cactcacggc aactttatta atttcttgga aagtgaaaac cgtgaagtcc 1231921 gcaaaaatgc gtttgacgca gtgtataaaa cgtacggaca atataaaaac acaatggcca 1231981 cgacgctaag cggcactgtg aaaaaggaca acttctacgc gagagtgaaa aagtacaagt 1232041 ccgcgcgtga ggctgcgctt tctaacaaca gtattcctga ggaagtatac gataaccttg 1232101 ttaagacgat taataagcat ttgccgctcc tgcaccgcta tattgcgcta agaaagaaag 1232161 tgcttgagct tgatgaagtg catatctatg acctgtatac accgcttgtg aaagatgctg 1232221 ggatgaaggt gacatacgag gaagccaaag attacatgct gaaaggcctc gcacctttag 1232281 gggaagaata tgcctctatc ctaaaagaag gactggaaaa ccgctgggtg gacgtttacg 1232341 aaaataaagg caaacgcaat ggggcttatt catcaggagc ttacggcacg aatccgtata 1232401 ttttgatgaa ctggcataat aacgtcaata atctctttac gctcgtgcac gagtttggac 1232461 attccgtaca cagctactat acgagaaagc accagcctta tccatacggc aattacagca 1232521 tctttgtcgc ggaagttgcc tctacgacaa atgaagcgct ccttggcgaa tatttgctga 1232581 acaatttaga ggatgaaaaa cagcgcttat atattctcaa ccatatgctt gagggcttca 1232641 ggggaacggt cttcagacaa acgatgttcg ctgaatttga acatctgatt catacaaagg 1232701 cgcaagaagg cgagccgctt acacctgagc ttctgacaaa tgtctattac gacctgaata 1232761 aaaagtattt tggagacggc atggtgattg ataaggaaat cggccttgaa tggtcgcgta 1232821 ttccgcactt ctattacaat tactatgtgt atcagtatgc gacaggttac agcgctgccc 1232881 aagcattaag cagccagatt ttgaaggaag gaaagccggc ggttgaccgt tatattgact 1232941 tcctgaaagc gggaagctca caatacccga ttgatgtcct gaaaaaagcg ggtgttgata 1233001 tgacgtctcc agagccaatc gaagccgcgt gcaaaatgtt tgaagaaaaa cttgatgaaa 1233061 tggaagagct gctgatgaaa gtcaagcagt cttaaaaaag taagcctgtg cggaaatgac 1233121 gcacaggctt ttttaaaacc ctttaaaggt tttccggtga ttcaagcggt agagggtaaa 1233181 caaaatagac agaaacagca gaggagaggt aatataaagc ggcagcatat gcatcatgcc 1233241 taagatattc aagcagaaaa aaacagcaat gcacacaatt gagatcaaag tagacatcat 1233301 ggcggtcctc ctcgtccttt ttccttataa ggatatgagt gaatgcactt cgttatgttt 1233361 tgtgacaaaa atatgaacat taagcataga ggttgtcaaa agtcgacatc ttttgttatc 1233421 ataaggatgt gaaattgatc acaaacaaac attacccctt tgtttgaccg tgaaaaattt 1233481 ctcccatccc ctttgttgtc gttaagacat atgaaaccgc gcttatcccg gcgcggtttc 1233541 tttagtgcta aaaatggaac gtacgtttgg ttatggcata aaaaaacagc ctcaagcata 1233601 tgcacgcctg cggctatttt tcacatgatt gatattcatc agaataagtg ctgagagact 1233661 tccaaaacat tccgtgtttg gcttccactt tggcaacctt tttagcaaac gccagttttt 1233721 tcatttcttt ttctacctct tcaaggctca ggtcatatac aagagcaatt tccttcgagg 1233781 caacgaagcg gaaatattca ataaaacatt ctaaaggcgg tgtttccgac ggcttcggct 1233841 cgtcgccaag catctcaaat aaaatttctt catatacatc atatgagtag ctgccaggaa 1233901 ctttaagccc ttcatcctca tgctgcgtat taaaaaacgt cagtgtcgga ttaacagaaa 1233961 catccatctc ggcagcaatt ttcatgtcac attgaagcgc cttgaccgcg ctttgagaat 1234021 gcagatcttt tttgaattct tcaagatcga gacttgtatt ttcagcaatc tccaaaagca 1234081 cgttttcatc cgtaatattt ttctttgaaa caaataggct ctcctgcata tttctgagaa 1234141 attgcatgcc ggcttttcgt ccttgcagtt cggctgcttt aaaagcgaga gcagccatat 1234201 aaggcgatga aagcggctga tcctgttcga accagacatt gccgtcacat gacatgccag 1234261 agcggctcgc gatcttttcc catgcttctg cgagaagatg cttttttcgc tttttattta 1234321 aagcggtaag gcttgcggaa gcgataatgc gtaaggtgaa aaaacgtccg tatctgattt 1234381 tcagcttttt gatgacgggc tctaaggacc agcattcagg acataaaggg tctacaaaca 1234441 tataaatttc aagcggtttt tttggatgac cgtggcaatg ggcgaagtat agctcatgct 1234501 gatagtttgt caagatgatc gatcctccgc ttccgtttga ttcaccatat gccttgctgt 1234561 caactccagc cggccaaaca aaaactcacg aatttcgccc tccagcccta catggtccat 1234621 tgcgtccttc atacagctga gccacgcatc agctctctcg tttgtaattg gaaagggaag 1234681 atgccttgct ctgagcatag gatggccgtg ttcctcagta taaagaggag gcccgcctaa 1234741 atactgagtt aagaattgct tctgtttcct ggcggtttct gtcaaatcgc ttggaaaaat 1234801 cggcttcagc aaaggatgag acgcgacacg ctcataaaaa gtatcaacaa gttgcgatag 1234861 aagttcctct ccaatcgctt cataaggtgc gttaaacgat tgtcccatgt tgactactcc 1234921 tttaaatatg gctaatagga atcataaatc ctattgcaaa aagtaatttt ctgtatttca 1234981 ttgtttcatc tagatttatt ttagcaacaa ggcatcattt ctacaaacaa actgcctttt 1235041 atgcgtttga tgactcattt cggctgacag ccggggtttg tatttcatat catatcacat 1235101 aaaaatcagg aatgcgtaag atttcacttc gcaaaaaaac cagagggaaa gagcacctct 1235161 ggttacgcgt aataaactga agttattttt tttacatagt tttgcgtttc ttggaaagga 1235221 ggaatgcctc cgtatcggtc aacattcccc ggtccggcgt tgtaagccgc taatgccata 1235281 gacacattgc cgtcgtattt atccagcatt tgttttaaat atttcgttcc gccctccaca 1235341 ttttgctgcg gatcaagcgg attggaaacg ccaagtgagc ttgctgttga cggcatcagc 1235401 tgcatgaggc ccatcgcacc tgctccgctg accgcttttg cattaaagcc tgattcctgt 1235461 ttgatgacgg cgcggatcag tttttcatca acgccatatt tatcagcggc ttttttaatc 1235521 gcactgtcaa tagagaagtc tcccgaacgg atctgatttg cttcatgttt gtttgaagct 1235581 gaatctgcaa cagctgtttc agtgctttct gccgcttttg tgactgaacc tgaattgctg 1235641 ctcgtatatg agttaagccc atacgctgaa agcagtgacg gcgctgttgt attcgcgctg 1235701 ttcagcatgc tgagcgggct tggcgatgaa gaaggtgctg attgctgaga tgtcagaccg 1235761 tttgtatatt ggctgagcaa agaactgaaa cttgaaagcg ggctttccgt attctgagtg 1235821 tccgagctgc tgcgtgcatt agatatggac tgtaatgcct gaagctgaag taatgctgcc 1235881 caattcgtta cattcacgat gtcattccac cttatataga ctttcgtttt tcttcataaa 1235941 aacgcagaat tttatttttg gtttcgcgct gaggaatgct gaattgctga agcagctttt 1236001 cgaaggcttg tctgccctca tgccaatccg ccgcctcaaa ttcaatttca tagtcctctt 1236061 tatttaaata tcggctgtgg tctaaaacta ttaagccttt ttctgtttct ttttccgcac 1236121 ggtttgttgc taaagatcca aagtattgta tggcatccgt atcgatctga agcttgtgca 1236181 gctggtcctt cacagggccc tcgggaactg aaaatccagc gagatctgat acctctgaaa 1236241 gctgctggtg cgtttccaga agccccacat cagccggctc ctttaatgta aggacatact 1236301 ttccgttttt tctgcggata cgaagcgcag catgtttttg tttcagcgcg aagctgtctg 1236361 tatcaaaata atgattcttt tgatctgtaa aatctttttc tgtcagctgg agtgccgatg 1236421 ctatgttttt gaattcttgt ttggtcagca tgtttttaaa ttcgatttca atctcttggc 1236481 tcatgatgct cttcctttcc gccctgtaaa tcttattttt actattatct ctttagatgt 1236541 taggtttatc aatatcgagc tcgatatgat aaaatgaatc tgtactttgt ttaaaaaagg 1236601 agagcattat gcaaaacaga atcgaaattt tgaatgcaac attatcggat gatcagcttc 1236661 gccttgcctg tcagacagaa ggaaacgaag cggaacgcaa gccgtcaggt caaatgcttg 1236721 ttgattctga ccactttgct tttgtataca tacttgaatt agctgattct tttgaatatg 1236781 tcattataaa ggaacatgta tggccggaac tgaagcaggc ccatgcacaa aaaataccgg 1236841 ttgttttaga ggcaggagac caaacaattg aactggcagg cctgcatgag gagctggaat 1236901 atcttttaga aaatataaaa gataatgcaa actatggaga agaaatggaa gaaaaagtga 1236961 aacgcgtgtt tttatagaaa ctggttcgga attgggggat gtatgatgga tgacaaacaa 1237021 tgggagcgtt ttttagtgcc gtaccgccag gctgtcgaag agttgaaagt gaagctcaag 1237081 gggatccgca cactatatga atacgaggac gaccattcac cgatcgaatt tgtgaccgga 1237141 cgcgtcaagc ctgtggcgag catacttgaa aaagcgagac ggaaaagcat accgctgcat 1237201 gaaattgaaa ccatgcagga cattgctggc cttagaatca tgtgccaatt tgtcgatgac 1237261 atccaaatcg taaaagagat gctttttgcc agaaaagatt tcaccgttgt ggatcagagg 1237321 gattatattg cggaacataa agagagcgga taccgatcat accatcttgt tgtgctgtac 1237381 cctttgcaga cggtatccgg agaaaagcat gttctcgtag aaatacagat ccgtacactg 1237441 gcgatgaatt tttgggcgac cattgaacat tcattgaatt ataaatacag cggaaacatt 1237501 cctgaaaaag taaaactaag gcttcagcgc gcttctgaag cggcttcccg gcttgatgaa 1237561 gagatgtcgg agatcagggg tgaagtacag gaagctcaag ctgccttttc aagaaagaaa 1237621 aaaggaagcg agcaacaata ggtaaagggg aagaagagca tgaaatttgc cgtatcatca 1237681 aaaggagatc aagtttctga tacgctgaaa agcaaaatac aggcgtattt attggatttt 1237741 gatatggaac tggatgaaaa tgaaccggaa atcgttattt cagtcggagg cgacggaacg 1237801 cttttgtatg cttttcacag atacagcgac cgtttggaca aaacagcatt tgtcggcgtt 1237861 cacacaggtc atctgggttt ttatgccgac tgggttcctc atgaaattga aaaacttgtt 1237921 cttgccatcg cgaaaacgcc gtatcataca gtcgaatatc cgcttctcga agtcattgtg 1237981 acctatcacg aaaacgagcg ggaagaaaga tacttagctt tgaatgaatg tacgattaaa 1238041 agcatcgaag gaagccttgt tgctgatgtg gaaatcaaag ggcagctctt tgaaaccttc 1238101 cggggcgacg gcctctgcct gtcaactcca tcaggcagca cagcctacaa taaggcgctg 1238161 ggcggagcga ttatccatcc gtctatcagg gcgatccagc ttgcggaaat ggcttcaatt 1238221 aataaccgcg tgttccgtac ggtcgggtca cctctgcttc tcccatccca tcatgattgc 1238281 atgattaagc cgagaaacga agttgacttt caagtgacga ttgaccattt aacccttctc 1238341 cataaggatg taaagtcgat ccgctgccaa gttgcatccg aaaaagtgcg gtttgcgaga 1238401 ttccgtccgt ttccattttg gaaaagagtc caggattcgt ttattggaaa aggtgaatag 1238461 aaagaggaca tatcgtggag cattttttta tcagaaagaa cattacttcc gctgaggacg 1238521 ggatgactgt aaaagaatat gccggtgaac tgggaatttc gaaacgtctg ctgaccgata 1238581 ttaagtttgg cgggggagac ctgcagatta acggtgagca tgtgacggtc aaatacgttt 1238641 tgaaagaggg agatcttctt atcgtgaagt ttcctgagga gcaggtgagc gagacgctgt 1238701 tggcagagcc tgttccgctc gatatccttt atgaggatga acatgtgctt gtgataaaca 1238761 agcagccgta tgtgtcatca atcccttcga gagagcaccc ctccggcagc attgccaatg 1238821 gaattattga tcattatcaa acaaccggag tgagggcgac agttcatctt gtcacccggt 1238881 tagaccggga tacatcaggt atcatgcttg ttgccaagca tcgatttgcc cactccattt 1238941 tatcgtctgc gcaaaaaaac ggccttgtga aacgccggta tgcggcagtg gttcacgggc 1239001 ggatggcaca gatggaggga acagtcgatg ctccgattgg cagacatcct gacagtatta 1239061 ttgaacggac ggtaacgcca gacggccaga aggctgttac tcatttttac gtcacatgtg 1239121 caaatgatga catgacctcg gtggcattgc agcttgagac tggacgaacc catcaaattc 1239181 gtgttcatat gagctatctc gggcacccgt tgtgcggcga tacactgtac ggcggaacga 1239241 gacaggaaat tggccggcag gctctgcaca gcgagcatct ttcgtttatc catccgctga 1239301 cacaggagaa catgaggttt catgctccac tgcctcagga catgagcaaa ctgataaaag 1239361 gagagaatca ttgattctct ccttttttat atggggcgaa atcttgattc gtcgtaaggc 1239421 agggagcttg gaacagagac ggtttctatt tctggaaagc gaaagcctgt cagttgattt 1239481 ccgaacacgc agcctgtatc aatgttgatg gtgcgattga ccttccgagg ctctttcaca 1239541 ggtgtatgac cgtataccac ccaagccttt ccgttatagg ctgccgccca atcacgcctg 1239601 atgggtctgc cgtccggata tgtttcaccc gtcacgtcac cgtaaagcac aaagtccttc 1239661 actctgcggg tatatttgcc gatatcgtca gctcttatgc cagcatgggc gacaactaat 1239721 tctccattat gtaagatgtc gtaaagcggc gctgtttcgt acagcttcat aaactgttcg 1239781 ctgactgatt ttttctcatc tttggaaagt tcctcaagct ctgccgctgt tgtttcgaga 1239841 ccatgcatca cttttaccgg atttcctttt aagtaacgat ataatttatt gcaatggttt 1239901 cccgggacat aacgcacagc gcctttttcg taagcgccgg ctacaaatcg gatgacctct 1239961 atcgatttgg gccctctgtc agttaaatct ccggcaaaaa caagcaccct gccttcttca 1240021 tggacaggta ctccattttt gattgtatag ccaagctttt ggattaatgc agtcatttcg 1240081 tcatagcagc catgaatatc gctgatgata tcgtaagcca tgcggtctcc tccttaccga 1240141 ttgttttatt tattatgaag caaagtgttg tgagtcatca caagctttta tgtgcaaatt 1240201 atagaagaag aatcattttc taaacaggat taagacctta tcactttatt tttcatcatc 1240261 acccttgtta aaatcgcgtt atgtttttta aaaatgaggt tttgttctct gagtgagaac 1240321 tagcataacc ctgacttaaa aaggaggttc tgattatggc gcatacatct gtcgcatctt 1240381 tagttgttgt acttatcgtt gcatttttga cacccatcct tttgcatcgg tttaaactca 1240441 gcatcccggt tgttgttgct gaaatcatta tggggctgat aattgggaaa agcggcctta 1240501 atttagttgt ggagggtgac acctggctcc agacactctc tatgctcgga tttatctttt 1240561 taatgttttt aagcgggctt gaaattgatt tttcgtcgtt tgagaaagga aagaaaaagc 1240621 agttcctgcc gaatggcaag gaagcgccga atacgtttgc tgcggcatct gttattttcg 1240681 tcggtatttt tattttatca ttgctcttgt cctatgggtt cgtcttggcc ggatttatcc 1240741 aaaatgcatt tttgatgacc ctgattattt caacgatttc attaggcgtt gtcgttccaa 1240801 cattaaaaga agaacggatc atgaattcga atatcgggca gattattttg cttgttgctg 1240861 ttattgctga tttggccacg atgattcttc ttgctgtttt ttcttcttta tacggagagg 1240921 acagcggaaa catgtggctc ctgatgattc tgtttgcggc cggagtggtg ctttactttt 1240981 tcggccgggt cttcaaacat cgctcttttg ttcaatccat gtcaaaaggg acgatccaga 1241041 tcgggacgcg tgccattttt acgttaatca ttgtactcgt tgccctgtct gaatcacttg 1241101 gggcggaaaa tattctcggc gctttcttag cgggggttct tgtttccctg ctttcgccaa 1241161 acaaagaact tgttcagcag ctggactcat tcggttatgg gttcttaata ccgattttct 1241221 tcgtgatggt cggtgtgaag cttgatattt ggactctttt ccaggataaa acaattttaa 1241281 tcatgattcc gctcctgctg cttgcgctgt tagtcagcaa aatcattcct gtcatgtact 1241341 taaagaagtg gtatgataac cgaaccattt tcgcgtctgg tttcctgctg acatcaacgc 1241401 tttcgctcgt gattgctgct gcaacaatcg gccagcagct tcacgtgatc agtacaaata 1241461 tgtcaggagc gctaatttta gtagccgtca ttgcaagtat ttttacgccg atctgtttta 1241521 aaaaattata caaacgggaa gagcagccgg aggagaaaaa gacgattacg ttcattggcg 1241581 ccaatcaaat gactttgcct gtcacactcg aattgccaga ggaagagtat gacgtgcgtg 1241641 ttgtacacgt ctaccaagag aatgcggagg aaaagctgtc agaatcagtg tttgctgttg 1241701 aaacaatttc tgactatgaa cacgagacgc ttgaatcact cggcattttt gaaacggata 1241761 tcctcgttgt ggcgacagga aatgaagata tgaatgcaga cattgcatta cttgcaaaag 1241821 ataaaggcac agaaagagtc attgcaagcg taggatcacc ggagcatgaa gcagctctga 1241881 aggagcaggg aatcagcatc ttttctattc tgctgtcgac aaaaacgctg cttcgcgcac 1241941 tgattgaagc gcctggcgtc atgaagctgc tcacgaacca agagtcttcg ctgtatcaaa 1242001 ttaatatgga gaacagtaaa tatgatggtg tcattttacg ggaattccct ttaacaggtg 1242061 acgtcatctt tgtcaggatc ttcagaggtg tggacagcat cgttcctcat ggggatacga 1242121 ggctgaaact tggagaccgt ttaattgtca ccggatctcg ggggtacgta acggatctta 1242181 agaaaacatt ggaaggataa atcttgacca aataaggatt cgtgttaata tagaggtgca 1242241 gaacaattca atatgtattc gtttaaccac taggggtgtc cttcataagg gctgagataa 1242301 aagtgtgact tttagaccct cataacttga acaggttcag acctgcgtag ggaagtggag 1242361 cggtatttgt gttattttac tatgccaatt ccaaaccact tttccttgcg ggaaagtggt 1242421 ttttttattt tcagaggggg aatgatttgt gaagttttca gaagaatgcc gcagtgcagc 1242481 cgcagaatgg tgggagggga gctttgtcca tccgttcgtt caaggaatcg gtgacggaac 1242541 gcttccgatt gaccgtttta aatactacgt acttcaggat tcctattatt taacgcattt 1242601 tgcaaaggtg cagtcatttg gtgccgctta tgcgaaggat ctttatacaa cggggcggat 1242661 ggcaagccat gcccaaggta catatgaggc ggaaatggcg cttcatcgcg agtttgccga 1242721 gctgttggaa atcagcgagg aagagcgtaa ggcgtttaag ccgtctccta cggcgtactc 1242781 ttatacatcc catatgtacc gttcggtttt gagcgggaat ttcgcagaaa tcttagcggc 1242841 cctgctgcca tgctattggc tctattacga ggttggtgag aaattgctgc attgtgatcc 1242901 ggggcatcca atttatcaga agtggattgg cacatatggc ggtgattggt ttagacaaca 1242961 ggtcgaggag caaatcaacc gctttgatga gctggcggaa aacagcacgg aggaagtgcg 1243021 tgccaagatg aaagagaatt ttgtcatctc cagctactat gaatatcaat tttggggaat 1243081 ggcctatcga aaagaaggct ggtctgacag cgccataaaa gaggtggagg aatgtggagc 1243141 ttcacgccat aacggatgac agcaagccgg tagaagagct agcgagaatc atcattacga 1243201 ttcagaatga agttgatttt attcacattc gggaacgctc aaaatcggcg gcggatattt 1243261 tgaaactgct cgatcttatt tttgaaggcg gtatagataa acgaaaattg gtgatgaacg 1243321 ggcgcgtgga tattgcactt ttctctacta ttcaccgcgt gcagctgcca agcggcagct 1243381 tttcaccgaa gcagatcaga gccagatttc cacaccttca tatcgggagg tcggtgcatt 1243441 cactggagga agcggttcaa gcagaaaagg aagacgcgga ctacgtgctg ttcggccatg 1243501 tgtttgaaac ggattgcaaa aagggtcttg aaggcagagg agtatctttg ctgtcagata 1243561 tcaaacagcg gatttccatc ccggttatag ccatcggggg gatgacgccg gacaggttaa 1243621 gagacgtaaa acaagcaggg gcagacggca ttgctgttat gtcaggaatt ttctcttccg 1243681 ctgaaccttt ggaagcagcc agacgatatt cccgcaagct aaaggagatg cgctatgaaa 1243741 aggcattatg aagcagtggt gattggaggc ggaattatcg gttccgcaat tgcttattat 1243801 ttggcaaagg aaaacaaaaa caccgcattg tttgaaagcg gaacaatggg cggcagaacg 1243861 acaagtgccg ctgccggaat gctgggcgcc catgccgaat gcgaggaacg tgacgcgttt 1243921 tttgatttcg ctatgcacag tcagcgtctg tacaaaggtc ttggagaaga gctttatgca 1243981 ttatccggtg tggatatcag gcagcataac ggcggtatgt ttaagcttgc attttctgaa 1244041 gaagatgtgc tgcagctgag acagatggac gatttggact ctgtcagctg gtattcaaaa 1244101 gaagaggtgt tagaaaaaga gccgtatgcg tctggtgaca tctttggtgc atcttttatt 1244161 caggatgatg tgcatgtgga gccttatttt gtttgcaagg catatgtgaa agcagcaaaa 1244221 atgcttgggg cggagatttt tgagcatacg cccgtcctgc atgtcgaacg tgacggtgaa 1244281 gccctgttca tcaagacccc tagcggagac gtatgggcta atcatgttgt cgttgccagc 1244341 ggggtgtgga gcggaatgtt ttttaaacag cttggactga acaatgcttt tctccctgta 1244401 aaaggggagt gcctgtccgt ttggaatgat gatatcccgc tgacaaaaac gctttaccat 1244461 gatcactgct atatcgtacc gagaaaaagc ggaagactgg ttgtcggcgc gacaatgaag 1244521 ccgggggact ggagtgaaac accggatctt ggcggattgg aatctgttat gaaaaaagca 1244581 aaaacgatgc tgccggctat acagaatatg aaggtggatc gtttttgggc gggactccgt 1244641 ccgggaacaa aggatggaaa accgtacatc ggcagacatc ctgaggacag ccgtatttta 1244701 tttgcggctg gccatttcag aaacgggatc ctgcttgctc ccgcaacggg cgctttgatc 1244761 agtgatctca tcatgaataa agaggtcaac caagactggc tgcacgcatt ccgaattgat 1244821 cgcaaggagg cggttcagat atgatgctac agctgaacgg taaagacgtg aagtggaaaa 1244881 aagacacagg tacaattcaa gacctgctgg cgtcgtatca gcttgaaaat aaaatcgtta 1244941 tcgtggaaag aaataaagaa ataatcggga aagaacgcta tcacgaggtt gagctttgtg 1245001 atcgtgatgt cattgaaatt gtccattttg taggaggcgg atgagcatgt taacaattgg 1245061 cggaaaatca tttcaatcaa gattgctgct gggcacgggg aaatacccat cgtttgacat 1245121 tcaaaaggaa gcagtagctg tttctgagtc tgatatttta acatttgctg taaggagaat 1245181 gaacattttt gaagcatctc agccgaattt tctggaacag cttgatttat ccaaatatac 1245241 gcttttgccg aatacagcgg gcgccagtac tgctgaagaa gcggttcgga ttgcaaggct 1245301 ggcgaaagct tcaggccttt gtgacatgat taaagttgaa gtcatcggat gcagccgttc 1245361 cttgctgcct gaccctgttg agacattaaa agcgtctgaa cagcttcttg aagaaggctt 1245421 tattgtgctc ccgtacacgt cggatgacgt tgtgctggcg agaaagctgg aagagctcgg 1245481 cgttcatgcc atcatgccgg gtgcatctcc gattggatca ggacaaggaa tcttaaatcc 1245541 tttgaatctg tcgtttatta ttgaacaggc gaaagtaccg gtcatcgtgg atgcgggaat 1245601 cggctcgcct aaagatgcgg catacgcaat ggagcttgga gcggatggcg tactgctcaa 1245661 tacggctgta tctggcgctg acgatcccgt gaaaatggct cgtgccatga agctcgcagt 1245721 ggaagcaggg cgcctttctt atgaggcggg ccgaatcccg cttaagcaat acggaacggc 1245781 aagcagtccg ggagaaggtc ttcctgtatg acaggcaggt attcaaggca ggagctgttt 1245841 gctccgatcg gcccatccgg ccagaaaaaa ttgaaagaag cgcgcgccgt gattatcggc 1245901 gccggcgcgc tcggaacagc cagtgcagaa atgctggtga gagcgggagt cggctctgtg 1245961 aaaattgccg acagagatta tgttgaatgg agcaacctcc agcgccagca gctttataca 1246021 gaagatgatg tcaaaaaaga aatgccgaaa gcagccgctg cggagcgccg tctccgttcg 1246081 attaacagcg atgttgatgt gaccggcctt gtcatggatg tgacagcaga aaatatcttc 1246141 gagctgatta gggatgcatc gattattgtg gatgcggctg ataattttga aacccgcctg 1246201 atcgtaaatg atgctgcggt aaaggaaggg attccttttc tttacggtgc ctgtgtaggg 1246261 agctacggtc ttacctttac cgtggtgccg ggttctactc cttgcctgca ttgcttgctc 1246321 gatgcacttc cgattggcgg agcaacatgt gacacagctg gcatcatcag tccggctgtt 1246381 ttgcaggtag cagtctttca ggtaacagat gcactgaaac tgctgacggg agaggagtgc 1246441 gagccggtgc tgcgctcctt tgatttgtgg aaaaacgagc ggtcagaagt gagagcggcc 1246501 agtctcaaac atgacgcatg cccaagctgc ggcacaaagg attttccgtt tttgtcttat 1246561 gaaaatcaaa caaaagcggc tgtattgtgc ggcaggaaca cggtgcagat cagatcatct 1246621 attacgaaag aagcggatct tgaagcgctt gccggtcagc tgaggcaggc cgggcttgaa 1246681 gtagctgcga acccgtattt aatttcctgc cgctcggatg atatgaaaat ggtgctgttc 1246741 cgggacggca gagctttgat ccatggaaca aatgatattg cccgggcaaa atccatttat 1246801 cataaatgga ttgggtaata aaaggagtgt agtgtaatga gtatatataa agcattgaca 1246861 atcgccggat cagattcagg cggcggcgca gggatacagg ctgatattaa aacctttcaa 1246921 gagcttgatg tattcggaat gtctgcgatt acggcggtaa ccgctcaaaa tacgcttggc 1246981 gttcacgggg tgcatccgct gactgtagag acgttgagac agcaaattga cgctgttgct 1247041 gaggatttga gaccggatgc agttaagacg ggaatgctct ggaatgccga catgattgaa 1247101 gaagtggcaa gaaaaattga cgagtacgga ttcaatcgtg taattgttga tccggttatg 1247161 atcgcaaagg gcggggcatc cttgctgcgt gatgagtcag ttgccacctt aaaggagttg 1247221 ctcattccaa gaagctacgc gattacgccg aatgtcccgg aagcagaaac gctgacagga 1247281 atgacaatca gctcgctgga tgaccggaaa aaagcagcgg agcagctcgt caagatgggt 1247341 gcgcagcatg tcattatcaa aggcgggcac cagcctgagg acaatcacat tactgacctt 1247401 ctttttgatg gcagcatgtt tatgcaaatc acccatcctt atatcaatac gaagcatacg 1247461 catggcacag gctgcacctt tgctgcggct ttaacggccc aaacggctaa aggagacagc 1247521 atccatcagg catttgaggt tgcggccaac tttgtccgtg aagcggtgga aaatacgctc 1247581 ggcatcggat cgggacacgg gccgacaaac catttcgctt ttaaacgaaa cagcttaaat 1247641 acaagccgat gagatcacca gctgatggtg atctcttttg cgtttgctac ggtatgcgct 1247701 tttcatctgg acaaggttat gatatgatag gaattaagat caggtactaa tactatgtct 1247761 ttattaaata taggaggctt tatacatatg aatttttcac ttgaaggccg taacattgtt 1247821 gtgatggggg tagccaacaa acgcagcatc gcctggggca ttgcgcgttc tttacatgaa 1247881 gcgggtgcac gtttgatttt cacatacgct ggtgaacgcc tggagaaatc cgttcacgag 1247941 cttgccggaa cattagaccg caacgattcc atcatcctcc cttgcgatgt tacaaacgac 1248001 gcagaaatcg aaacttgctt cgcaagcatt aaggagcagg tcggtgtaat ccacggtatc 1248061 gcgcattgta tcgcgtttgc caacaaagaa gagcttgtcg gcgagtactt aaacacaaat 1248121 cgtgacggct tccttttggc tcataacatc agctcatatt ctctgactgc tgttgtcaaa 1248181 gcggcacgtc cgatgatgac tgaaggcgga agcattgtca ctttgacgta ccttggcgga 1248241 gagcttgtga tgccaaacta caacgtcatg ggtgtagcaa aagcttctct tgatgcaagt 1248301 gtgaaatatt tagctgctga cttaggaaaa gaaaatatcc gcgtcaacag catttctgcc 1248361 ggcccgatca gaacattatc tgctaaaggc atcagcgatt tcaactctat cttaaaagac 1248421 atcgaagagc gtgcaccgct tcgccgcacg acaacacctg aagaagtggg cgatacagct 1248481 gcgttcttgt tcagcgatat gtcccgcggg attacaggtg aaaatcttca cgttgattct 1248541 ggtttccata tcactgcccg ctaagcagga tctatatcaa gcaatcccga atagggattg 1248601 cttttttatt tcttctgatt ttcagctttc tgtcatatag atagaatatg acacaatcgg 1248661 agggatgaag atgtctaata agaaaagaaa cgcggataaa aaaccgctca tgtatattgt 1248721 tcagccggat tatgcagaaa ctacaaggtc atccatgcag gagattgtca tcaaaagaaa 1248781 ggccgacaaa cccgctccgc caaaagctga ggaaaagccg gcttaccatg agaagcagca 1248841 ggaggaagcc gtggcacagg atgtcctgca agaagaccaa aagcctgcag ccgaaccagt 1248901 gagtcagcaa acacaagagg cgagagagcc agagaacata aaaagccaag aggaacagaa 1248961 ggcagagccg caggccgtag aagaaaccgt tgaacacgag cccccgaaag cagaaaaaaa 1249021 ggaagagcct gcacttgagg cccggaagcc tgagaaagaa ccggaagctg tccatagtgc 1249081 tgataaagcg gaggaaaaag caccgccggc acgaaaagtg aaaaaaccga tgagcaagat 1249141 gacgatccac gaaaaaattg attttttaac aaagctgcct cataacatgc cgagagcgct 1249201 ttgtttgatt gaagccaatg gaagaacgta caggggcgtg attgtcggaa gaagaaatga 1249261 ttccgtcctg cttcgaacaa ccggaaacgg agccccaacc gaactggcaa tcgatgatat 1249321 tacctctttg cacccgctcg gtttttaacg aaaaagaaaa aagctgcccg gctgatgttg 1249381 ccggacagct ttttttacat agagaaaagc ctgcaggcct gcaagctttt ccagcttatg 1249441 attaatgatg atgtgtacga ttgattaatc gaggatttaa gcagttgatt gcgcagaagc 1249501 agtctaagtc aacttcaata cagtagttcg ttttttcgag tcggaacact tcacacaccg 1249561 tatctttatc ggtgaagtcc aaaatgtgtt tgtgttcgtc aaatgcgatt aataatgaca 1249621 gtgttgcaca gcttccatgc actctttcga ccctgaaaaa tactgtatta aagcaagggc 1249681 cgttatcgag ttcgccgaca tttccgaagg cgactaatgg cgttgatttt gatgtaaata 1249741 ttgcaaaagg cactgtgtcg cctaacgaat ggcttacaga taaaagctta gagtggcagc 1249801 cggtcgggca gtcttcttca acagcgtttt gcagatcttc aatattttct acagcttcac 1249861 gcacgcagct tgatgttttc tggctcatat tatccctcct gccttataaa tttgagactg 1249921 gcgaaatgat ggagagtcag ctgcctcacg ctggaagcag ctgaatgatt tgcacctgta 1249981 atagagtttg gaaggggatt cctctttaca agtgtttatc cattgtgatg atgcttttta 1250041 tctttgtgag gcgatgttct gtcaactagc tctggtgaca ggcactgaat cgcgcagaag 1250101 catccgagat ccacttcaat gcagaaatct gttttttcta gcccgaagaa atccgggtcg 1250161 caagggtggc aaacacttaa ggtatcgcct ttgacatcga ccgggcgtaa aatagacagt 1250221 gttgcacagc aatcgcataa tttttcgacg cggaagaaaa tggattcaaa gcattgcata 1250281 tcatccacaa atccccctac gtttccgaat gtggagaaca atccgccttt tttatcaaaa 1250341 acgagaaacg gaattgtgtc ttttccagca atcgtagggt ttaaaaggtt ggtatagcag 1250401 ccagtcggac actgttcttc aactgcctcc tgctctgcta aaatcttttc cactgcatcg 1250461 catacacagt tctcatgccg gccatgggtt tttccgcagc tcattgattt cagctccttc 1250521 tttatagggt atttgacttt agtccttaac aacatatgta cccgtgcccc acttggtgtg 1250581 ggtgaacgtc tatatattca tcatatgctt ggaaaataag aaaaagcaga gcgtttttag 1250641 ctctgctttt aggtcctaga ggacaagagt gataactagg atggctacga gtgtatttgt 1250701 tgctgtagaa ataagggttg cgatatcggc atctactgtt gtgacgttta cgccgcggga 1250761 acattcgatg agaagttttt ggcggtttac ttgtttgtta gctgtaagct gtaacaaatc 1250821 ttgtgcgact aattcggcaa ttacgccgtc tgcaattgat gtcagagttg ccgttacgac 1250881 agcggcatta agtgctgtta caactgatgt tacggcttga acgtctgtag atgtaacatt 1250941 gatgtcacaa gaatctctaa taataatcgt ttcatctgaa acttgtttgt tgagatttgc 1251001 ttgagctaga tcttggtcga tgaaggcgtt gtcgttgcca aaaaaaccat tgccattaca 1251061 gcaaacgtcg caatgacatt ttctttcgtg tttttcttta tctttctctt tgtcatctaa 1251121 cggatggtca cagtcaggat caagtgcaac ccaagaatat ggtctgcttt ccatatctat 1251181 tcctcctttt cttttactgt tattaaatga gcgagcctct tattttgact gagtcatata 1251241 tcctgatgaa gaaccctatt ttttatgatt ggctaattgt tatcgttttt ccgtctttgt 1251301 ctgatctgtt caatgagctg ctctctgcgg cttaacggtt ttgtgttctt ttgctcttgt 1251361 gcggctgctt cttctttttt cttcttttgg ttttctatta gcgcttgtga tttagcttgt 1251421 aagtctttta caagatttaa gagcatttct ttttcttcgt ctgatacttt tttcattttg 1251481 tcttttgtga ccccatgttt agaaaatata ttttggacca gcattttcgt cattggatca 1251541 acttctggaa gctttgcaag ctcttctttg aatttatcgt tatctgacat ttgttttcac 1251601 ctcgtctttt aagtttgtga aaagaaaggg ttaaaggacg tcaagttcac taagaatgct 1251661 gtttaacacc tgaagcaaga tttgtacaaa ggttattatc tcgtcggcag acaaagtaat 1251721 tttgatgttg cggctgttga taattttaat gatggttctt tttttgattt gggagctatc 1251781 gagaataaga atttcacttg ccactgcgtc agccaaatcc tcgtcggcga tgacgagctg 1251841 agtcgccacg ataatcatgg ttgtcacaaa ggcttgtata gaaagggcag ctgttatatg 1251901 tgacgtgtca attgtgatat tttcgcaatc aatcacttcg atctgctgtt cgaattcgct 1251961 tgataattgc tcaaatattg cagggtgcag ggattcgact ttttcttcaa atgacataac 1252021 cttcactcct ttcttatcca tactctatat aatgcaaatg gggtgcagag cggaataata 1252081 aaaataacca attttctgcc ggacaagata caattcatga agaatagggt tttggcatat 1252141 atgtgaaggg atcatgattg gcaaaggagt gaacgagtgg ttataaatgg gctgacaatt 1252201 gttcttctat cgcttgcggt ctttcggctc gcccgcctgc tggtgtttga cacgattatg 1252261 gcgccgcttc gcagtctgtt tcatgaagag aaggaagaaa aggatgcgga cgggaacatt 1252321 gaaacctata tcgtgattaa gggaaccggt gtcagggcgt ttattggtga attgctgagc 1252381 tgctattggt gcacaggcgt gtggtgtgcc ggctttttga ttttatgcca ggcggtgatc 1252441 ccgcaagcgg cgcagtggct gattttactt ttggcgatcg ccggccttgc cggcattata 1252501 gaaacgctcg tatcaaaatg gctgcaagaa taaggcgtta ccaccagcaa ctttctgtca 1252561 gaatacgcat aaagtagcat atatgacata aggaaaggaa ggggacaaaa atgaatcagc 1252621 atcataaacc ttcccaaaaa tctccatata cagattcatc gtatcaatca aaaaagataa 1252681 aaaagaaagg ctgcgggtgc ggaaataaaa agaaaaagcc tcaatagcct ggcaaagaaa 1252741 ccggagaact ccggtttttt gtttttttaa cgaggcggtc tcgctcagca tatatcataa 1252801 gcggggggat aaaagtgaat gagtttgaaa aatggataga aggaagatat gaaccacatg 1252861 aacaaaagca aaaagagcat gaagacacga tgggcagtat cagaaaagac ttggatgcat 1252921 ttgataaagc cggtctggaa tttgaagatg agattgaaga gctggctgaa aaaacggagg 1252981 ccttacttaa aaaacatcaa gctcaatatg atcaatcgta aatccgcaaa cgccctatgc 1253041 gaatatccaa gccgatccca gcagctcaca tagtgtatag agagtaaagg aggtgcttat 1253101 ctatgggctt tggatacgga ttcggcggcg gctacggcgg cggctgttat ggcggttatg 1253161 ctggcggtta cggcggcggc tatggttcaa catttgtttt gttggtcgta ttattcattc 1253221 tcctcatcat cgtaggtgca tctttctttt aagatgtatt gaggaagtac gggttataac 1253281 ccgtacttcc ttgccttgtg tttattttta aaaatgttgg aaaagcacat tgtattatgt 1253341 gcattcatac aataccgtat tactccgcca aaaggaggcg cattatggat aatcaatttt 1253401 ttaagaacat cgaaaagaaa acaggtgtga agatgcagga tgtaatgaat cttgccggat 1253461 cactccaaaa cgctaatttt aaagatgaaa atacagtgcg cagtgtgatt aaccgcgtag 1253521 cgcagatggc aaacagacgc gtgccaaaag aattagaaga taaaattgtg gaatctatta 1253581 caagcggaaa agaaaagctt gattttggca cgatttctaa aatgatggat aataaataag 1253641 tggatggcct ggctgactca ctgcagcggg ccttttttta cagtaaaaac ccggcagtaa 1253701 tctgccgggc tgttaatgat gcaagggctg tcttgctttc tgtagcaggg gatacaaaaa 1253761 tcttgagcgg ttggctgttt tgccgcgcct gttagcaggg caagacaaat ataaatgctg 1253821 tttcgcccgg gtcatggcta catataaaag gcgtctttcc tcctcaagag cggcctcgtc 1253881 tccttttctt gccgtttcta atgagaaatc gtgcggaatc gagccatcta cagtgcctaa 1253941 cacgtagact gttttgaatt caaggccttt tgaccggtga atggtcatca gctgaacgcc 1254001 atgttcatcc gttctgtttt tctcagcggc cctcatatgg tctacgtggg caagaaagtc 1254061 aggaatcgtt ttgaacttct tggcgacaac cttgatgtcg cgcaggtcat cagagccttt 1254121 ttccagcttg ttgccctcat tgccccgctt ttttaaatac tcggagaagc ccatttttcc 1254181 ttctgcaaag gtgatggctt ctacgggttt cattgtgcgg aggcttgcaa aaaacggtac 1254241 gattttcttg attttgtcca gctggaatgg cttcagatca ggcaatttgg ccagcgcttt 1254301 gatcatggta cagtcctctg taatcgagag cgccttcagc gtattcaaag cggactgttt 1254361 taaaaacaag gcgggaagca agtgtttaat cgcctcggtg tcatcctcat tttggctggc 1254421 gtacaagtag gcgagaatct ggcggacgat ccgtctgctg taaaacgatt ggacgccgcg 1254481 gtcagctgta tacggaattg acgattgatg aagcctttca tatatagcac ggcctccgct 1254541 gtttgtgcgg taaagaaccg caaagtcttc tggactggct ccattttgaa ttttttcttt 1254601 gatatcggaa acgaccattg tggcttcttc ctcttcatca taaggataaa acagcacagg 1254661 gacctgaatg tcatcgcggg ccgcttcaag cgttttggca tatctgtttt tgttcttttt 1254721 cacaacgata tcagcactag agacgatcgg gtgcgtagac ctgtagttcg cagttaaata 1254781 gatcgtcttc gctcccggat aatccttttg aaaatcaaga atgaaagacg gattgcttcc 1254841 gcgaaacgcg tagatggact ggtcatcgtc tccgacacag cacaggtttt gctccgggct 1254901 ggcgagcatt tgcatgattt tgtattgaac cggattaatg tcctgaaact catcaattaa 1254961 gatatacgta aaccgagatt gatattgttc cagaaggtca ggccgctcga taaacaattc 1255021 atagcaggct gaagccatgt catcaaaatc aaattggctg tgttcttttt tctggcgttc 1255081 ataatgttca tataaacgat aaacttgttt ttcccactca tcttttagag ggatgcgttc 1255141 atttgggaca taagtgtttt tccaaaaacc gatctgctgc agggcttggt caactgggga 1255201 ttctttctca tcgatgcctt cttcatagag tgcttttttg atatattgtt cccgctgcca 1255261 ctccattttc agcagatgct caccgttcca tttagcagaa ttagagtgat acaagatctt 1255321 ataaaacaga ctgtggaatg ttcctgtcac aattcttctg acttttgccg gctgtaatcc 1255381 gtactggttc gccatacgct ctttcatttc agcgacagct tttgttgtaa aggtgacaag 1255441 cagcatattt tcaggcggta tgcctaagtg ttcgatcatg tgggcggcac gggctgtcag 1255501 tacccgtgtt tttccgctcc ccgcacctgc aagcacgagg agcgggccct ctgtttccgt 1255561 gacagctttc agctgatccg tgtttaaacc gacagacgga aaaaggctcg tatcgggttc 1255621 tattgttttt ggcacaaatg gtgttcctgg tttaatgctt ctaggacggt gccattctgt 1255681 aacagctggg gacgggtcag cggcgatcgc ttttcccttg ggtaaacgaa tgacaccaga 1255741 ttcctgatca tcttcttttt tcccctcttt agagggcttc ggttcgcacg cctcctcaca 1255801 tgccggaaaa tcgcctggct ggcgatggat aaactctggc ggatcggcga tgttaagccg 1255861 taacaaaacg ggctttccgc aatgagaaca aaataaatgt ccttttattc cctcttcaaa 1255921 gaggaattga taatgttctc tcgaatatgt atgtaaatgt atgattctat cattcagtcg 1255981 ggcgcatttc aaaaaggggt cctcccaatc aaaaggtgtt cattacagac aatgactatc 1256041 atatcaaaag aaatgtgttt caaaaagtaa gtttaaggga aaagagacag cagaggggtg 1256101 ggtattgtat gatatatgca ggtcaaattc agaaccagca atacgctcaa tatgctaata 1256161 gaacgattgg acataagcag gattatgccg gaaccgaaaa aatcagctat gtcccgtttc 1256221 agcgggtata caaagaactg gaaaagcagc aggagaatca aacggcagct gaaagaaaag 1256281 taaacgagat gaaacgtaag cgctctcttt ataagagatt gcgagaaaaa ggaatgggga 1256341 catatattaa tcgatatgta taaaaaaccg ttcataccag agaacggttt ttttatatgc 1256401 agtaaaaatc cggatctcaa aagatccgga tgcgttcagt ccttcatcat ttgtaagtgc 1256461 ggaatgccgg catcgaggaa ttctttttca gaaagcacgc gatacccgtg tttcttgtaa 1256521 aacggcacag cctgtgtttg cgcgtttaaa atgaaaccgg aagcgcctcc gtctgccgcg 1256581 gctttttcga gcgctttcat aatgatgccg ccgacaccgg ctgagcggtg gcttttcagt 1256641 acgcaaatcc gctctaactt gccgtagccg tccttcatgc gccatcttcc ggcaccgaca 1256701 ggcttttcac cgtcatacac gacgatatgc tctgactcat tttcaagttc gtcaatttct 1256761 tcttcagcag gcacgttttg ttctttgaca aagacttctt ctcttacata gaatgcatct 1256821 ttcagttgtt cttcattttt tgcgataact gctttcaaac attattctcc tctgcctagc 1256881 aagaaggttt catatactgt ccacgatccg ttttccaact ggtagagcaa gtggaaacgg 1256941 tcaacgattt cttcatgcga cacttcctgc atttttaatt gtcccagcac atctgaatgc 1257001 tcatcgtcgg aaagattttg gccgaccgtc acatgcggaa cgaaattata ttcctgttct 1257061 cctgccaaca caccggtgta tagcttttca ttgagtgttt ttaactcttc cgtcggttct 1257121 gctttgatgt aaatgacatt attgacaggc gcaaatgagc tgtattttgt cattttgaga 1257181 acgagtgggt gggactcttt tgcgatgttt cttaaatgtg atacgagctg atccgctttc 1257241 tcctccgcgc attcaaagga tgctctcagc gtcaaatgag gcgggattag agagtagctt 1257301 gggtcatagc gctttctgta agagtttgca aggtcttgga gcttttttga tggaaataaa 1257361 acgattccgt atttcatatt atgtccctcc tggaaataaa gtatgataga gtgttaaagc 1257421 atttttttca gcgccggggt gatgagcggc tgccagtatg tccatttgtg gtctccgtca 1257481 aatggctcga aatcataatc ggaaagcttt ttctccagca gctgtttcag ctcccggttc 1257541 ggttctgtaa agtccagaat gttcccgtct gtcgtgtgga cgtcagtttc ttttgttccg 1257601 atttggtgat aaatagagag gtgtttgata tcgtctgact gttttacggc ttctagtacg 1257661 tgtttgtcaa catagggaga ctgcatgatg atgttgccaa acatattcgg ataatcaagc 1257721 gctgtcataa gtgacacggt tgctccgagc gaatcaccga tcagcgttcg gccgtaaccg 1257781 atctgatagg ttggatactc atcatctgca aaaggaacga gctcatgggc gatgaaccgt 1257841 ttataagccg aaaattttga accctccgga tgataagtgt ttctgcgctc ttttacatcc 1257901 ttatagggaa caccgataat aatgctccgg tctatttcgc gtttcgacag caattcctca 1257961 acctgtctgc cgattctccc cagcctgaaa taatcgtggc cgtcctgcgc gataatgaca 1258021 tggtatttat aaagcgggga gtagttggac ggcagataaa caagcaaggt catttcctcg 1258081 ttaagctctt ttgaaaagaa tttcttttct tgcactgtgc cgtttttcgg tgccataaaa 1258141 acattcctcc aggacatcac tatactttct tgcattttca attattgtac catgaattat 1258201 tagaaatttc tctctttaaa cggttcggca cacgaagaaa aaagtgttga aataaactgt 1258261 gaattgcgct aatataaaac aatcagaaaa ttgaaatcga tatttcttat cgtgagaggt 1258321 ggagggactg gcccttagaa acctcagcaa ccggcttgtt ttgcatttgc aaagcgccaa 1258381 ggtgctaaat ccagcaagcg ttttttatgc ttggaagata agaagaagcg ttaaacccct 1258441 tcttcttatg aagaaggggt ttttattttg aaaagggaag gtgtcagcta tatgtcacag 1258501 cacgttgaaa cgaaattagc tcaaattggg aaccgtagcg atgaagtcac gggaacagtg 1258561 agtgctccta tctatttatc aacagcatac cgccacagag ggatcggaga atctaccgga 1258621 tttgattatg tccgcacaaa aaatccgaca cgccagcttg ttgaggacgc gatcgctaac 1258681 ttagaaaacg gcgcgagagg gcttgccttt agttcgggaa tggctgctat ccaaacgatt 1258741 atggcgctgt ttaaaagcgg agatgaactg atcgtttcat cggacctata tggcggcacg 1258801 taccgtttat ttgaaaatga atggaaaaaa tacggattga cttttcatta tgatgatttc 1258861 agcgatgagg actgtttacg ctctaagatt acgccgaata caaaagcggt gtttgtggaa 1258921 acgccgacaa accccctcat gcaggaggcg gacattgaac atattgcccg gattacaaag 1258981 gagcacggtc ttctgctgat cgtagataat acattttata caccggtctt gcagcggccg 1259041 cttgagctgg gagctgacat tgtcattcac agcgcaacca agtatttagg cgggcataac 1259101 gatctgcttg ctggacttgt cgtggtgaag gatgagcggc tcggagagga aatgtttcag 1259161 catcaaaatg caatcggcgc cgtcctgccg ccatttgatt cgtggcttct gatgagagga 1259221 atgaagacgc tgagcctcag aatgcgccag catcaggcaa acgcgcagga gcttgcggcg 1259281 tttttagaag agcaggaaga aatttcggat gtgctgtatc ccggaaaagg cggcatgctg 1259341 tccttccgtc tgcaaaaaga agaatgggtc aatccgtttt taaaagcact gaagaccatt 1259401 tgttttgcag aaagcctcgg cggggtggaa agctttatta cataccctgc gacccagacg 1259461 cacatggata ttcctgaaga gatccgcatc gcaaacgggg tgtgcaatcg gttgctgcgc 1259521 ttttctgtcg gtattgaaca tgcggaagat ttaaaagagg atctaaaaca ggcattatgt 1259581 caggtcaaag agggagctgt ttcatttgag taaacacaat tggacgctgg aaacccagct 1259641 cgtgcacaat ccatttaaaa cagacggcgg aaccggggca gtcagtgtac cgattcagca 1259701 cgcctcgact tttcaccaat cttcatttga agagttcggg gcatatgatt acagccgctc 1259761 tggcacgccg acaagaacag ctctcgaaga aacaattgcc gcactggaag gcggaacaag 1259821 aggatttgct ttcagttcag gcatggctgc catctcaaca gcatttttac tgctgtcaca 1259881 gggtgatcac gttcttgtga cagaagatgt atacggcgga accttccgta tggtgacaga 1259941 ggtgctgacc cggtttggca ttgagcatac gtttgtcgac atgacggatc gtaatgaagt 1260001 ggcgcggagc atcaagccga acacaaaggt catttatatg gagacgccat caaatccgac 1260061 acttgggatt acggatatta aagcagttgt tcagcttgca aaagaaaacg gctgcctgac 1260121 ctttctggac aatacattca tgacgccggc actgcagcgt ccgcttgatc tcggcgtgga 1260181 tattgtactt cacagcgcga caaaattctt aagcggacac agcgatgtgc tctcaggttt 1260241 ggctgctgtc aaagatgaag agcttgggaa gcagctgtat aagctacaaa acgcgttcgg 1260301 cgccgtcctt ggcgtgcaag attgctggct tgtcctgcgc ggattaaaaa cattgcaggt 1260361 ccgtttagag aaagcgagtc aaacagctca gcggcttgcg gaatttttcc agaagcaccc 1260421 ggcggtcaag cgcgtgtatt atccgggact ggctgatcat cccggcgctg aaacccataa 1260481 aagccagtca acgggagcgg gcgccgtgct atcttttgag cttgaaagca aagaggccgt 1260541 taagaagtta gtcgagaatg tgtcactccc agtcttcgct gtcagccttg gcgccgtgga 1260601 atcgattttg tcctatccgg caacgatgtc tcatgcggca atgcctaagg aagagcgtga 1260661 aaaacgcggt atcactgatg gcctgctccg tctgagtgtc ggcgtcgaac atgcagacga 1260721 tttagaacac gatttcgaac aagcgctgaa agaaattgct ccagtttcgg ttcgttaaaa 1260781 aagaagccgg ggatagtccg gcttctttta ttattgttcg tcatcaggat tcagaatcgc 1260841 gaggacttga tgatcctccc aaacgccatt aatttttaca ttttttcggg cgatgccttc 1260901 tttatgaaat cccgcttttt ctaaaacacg catggacccg agattacggg gcatcacacc 1260961 ggcttcaatc cgatgcagtt tcaattcgtg gaacgcataa tcaacaacca atctgactgc 1261021 ctctgtcata atgccctttc cattatgggc tttgtctaaa aaatacccga tgaacgcagt 1261081 ttgcagcgcg ccacggatga tttgaaagag cgaaaccgtc ccgattaatc tatcgtctga 1261141 cgctgtaaag atgccaaaat gatattcttc atctttctca agtctttcct gatactcggt 1261201 tattcgtttt ctttgcccct caaccgtata gtaatcgtct gcgcgtatca tagaaaactg 1261261 ttcgaaaaaa tctcgatttt cgctttgcag ccccagattt tcttcggcat ccgttacttc 1261321 taaaggtcta acataaatgg tttttccttt taacatatag tgatctctcc gttctcatgt 1261381 cagcattcct cttacattat tctcagggaa atgcaaatat cctttttata agaaggaaga 1261441 aaaccaattt cccataaaag tgccaacata gttgccgatt aagtagccga gcgtaccgac 1261501 aagcatgatc ggggcgacaa gctcccgcca tcccttggca attgccatcg cagccgcagt 1261561 cgtcggtccc ccgacagtag cgttgacggc gagcagaatt tcttcaagcc gcacacggaa 1261621 caattttccg gcagctaagg aaaccgctaa attgctaatc gcaatgataa acacgaataa 1261681 tagaataaga ggcgcattcg tgacgattaa gcggagatct gcaggaatgc cgatcaccac 1261741 aaaaaacaaa taaatcaaaa aggttccaag ctcctgagat ccattgagcc tttcaaaaaa 1261801 acgcgggaaa agaaaaatga taagaacagt taaagacgta agaaccaggt actgatcgcc 1261861 aagcgtaccg gtcagcaggg gatgagaaaa aatgctttta aaataaccgg aaaccttcat 1261921 actaaccgca acaagcgcga aagcggcacc ggcattaaaa gcgatatcct ttaaggaaat 1261981 atccttccgt ttccaatagc tttcagcact gtttccgctg tttccatcgg cttttacctt 1262041 ctcttcaaac ggcatggcat aatgccgctg aaaccatttg agtgcaggaa tgctgattaa 1262101 aataaaaaac aaaagcgcca tcataaaatt atcagccaca acggtagccg acacatattc 1262161 accaggcgtc tcaaattttg ccgccatcgc cgcaaagttg accccgccgc cgatataaga 1262221 ggcgctgatc atcccaccga ttttatctaa gtaaggaata tgctgtttga gtagaaaaaa 1262281 agccaggata ctgccaagca ctgttccaac ggagctaatc agaaaaataa acagcaaacg 1262341 cctgctttcc ttaaaaattt gcctaacatt gatctgaaac aataaaagtg gtatcgccag 1262401 cggtaccaca taagaccaca cagtgtcata cacgggcgac tcaacaggaa gcactcctac 1262461 atttgtaaac accatagcac ctgcaagggc gataatagcg cccgacacag cagacgccca 1262521 cttaaagcgc tgctccagcc cgatgctcac tgccgcccac accgcaataa acccccataa 1262581 tacccataca tcatcagaag aaatcaaaga atgcaaaacc ccatcacctc tattgttaga 1262641 aaattaagac atattataat agccggggaa cggaacagca agtccaaaaa aagtttttct 1262701 aaaaaagcag ttgacgaata gaaggtaagg ttatataata gaacttgtca gaaagataac 1262761 aacataccca gcaacacata catatcatga ttccgtagct cagctgggag agcgctacct 1262821 tgacagggta gaggtcgctg gttcgagccc agtcggaatc atagcttaaa cccttgcgca 1262881 gcaagggttt tttactttgc gttaataaag ccggttcgtc aaattcgtga gttgttggcg 1262941 aactgttggc gaaattcatt gaccgcagtc caaaaactac ctccaaactt acttgattag 1263001 ttcaatagta acaaacggaa gatcggattt ctgttaaatc ttcattgaga atagccagtc 1263061 caagaccgtc acttcagcca tgcatctttt aaatgaaatt ttgtactgaa aacatcaatt 1263121 gtatttttaa attctgctct agaatcagcc cctttataat aatcttgata aattgcttgg 1263181 ggtgatactg attcgtgatt tgtgctatgg tttgcaaggc ttgtagcaaa agcaggagca 1263241 acagtaacga gtaaagcaag ggataatgca aaaccagtta aagctttttc aatttcattt 1263301 taagcacttc tttttttaaa atacaacttt attattaaat ggaatacaaa aacatccaag 1263361 gtgttttttt gttagtaagt tgagttaggg ggattggatg gcacttagaa tattgtttct 1263421 gctgatggga tgttgattct ggatatattt ccaacacgat tacaggccgg acatgaaagc 1263481 gaaccttgct ttgatcgggg caatcatttc atttacggct gcggtttact ttaaagatat 1263541 tgatgtattg agagaagagg gaaaacaaat gaacggaatt tctgagcgtt ggaacacgtt 1263601 taaattacaa aaatcccctg aaccactcta gatcagggga ttgctttccc aacagcttat 1263661 taagtagcgg aaggcatgat caacgattta gtatcaattt attaattgcg aatactagaa 1263721 acataccgtt ttccgccttc cttagaagta acatattctc gaggaacatt aagtctattg 1263781 gtagaatgat aacttacata aagtttcata tttgctcggc tcgttacgat agccgtatga 1263841 tccatccaac catcagcata gcgaagacct attttattat ggtaatcata gtgatataca 1263901 tctccaagct ttacatttga atatgtatca gaaacagtct tcatttttat tccgccagct 1263961 tttaaaatgt atgatctaaa ggctcctgca ttaacccaag catctgtata gggtttccat 1264021 tctttaaagt acggcattct tccagctctt aatgcttggg aaacaaagtt agtacaatct 1264081 ttgtctttat aatatttata gtttttattt ggttttaagg catatttttc tgcatatttc 1264141 attgcagcgt aaccactata tcctttaaca gatgttgcag tcacagttag ttgattagag 1264201 ttagcagcat tgaagttcat acttactggt ttatcttcac ttttcacttc ttctttatca 1264261 tcatttttca cttcttgctt atattttttt aaaaattcat ctaatttaac atccgaagaa 1264321 tattcttcat cattttcata ttgtagagtt gaagaagaat tatttaattg tgttacattt 1264381 agttgcttag aagaattact caatggtatt acatttagtt gattagaaga atttttaact 1264441 tgagagaaac ttagattaga agtatttgtt gattgagaac tttgtttatt agaagttgtt 1264501 ttgggaattt caagtttaat attatcgccc agagatgttg ttactttttc aacaccaaaa 1264561 acaaagtttc gagtaatata agcttcaaca attagcttat tgtttttttc agaagtctta 1264621 acatcgtcta tatcgtatgt aaactcgtgg aatttttgtt tgtccacttt acttaacgca 1264681 gaatacagta agactccttc gtcggaatca gtcaatttag actctttagg atgcgctaaa 1264741 ggagtgttgt gttcaaaatc atatttttgt tgttctaaca tatccttaac tttttcgtaa 1264801 ccaatctcgt tggtaattga aacattttct ttagtctctt tattagtagt ggctgcaaaa 1264861 acttcatttg ttgacactaa tggtgacaat gatagacata aaactagtga agcaagtaat 1264921 tcttttttca tacgaaacct ccaataaaat ctaaatataa gtaatattta tcatttacac 1264981 caattgaaat atggcataaa atacatgtaa taatataaca taaaaataaa tacataaaaa 1265041 ggtatcggag gaaaaaatga aaaagaaaac taaaattata ctttctctct tggcagcact 1265101 tattgttata ttgatagtac ttccagttct atctcctgtt gtctttacag cttcttcgga 1265161 aaaaggagca atcagacacg aaatttataa aagaggatat ccctaccaaa gctactttgc 1265221 agttctccag aaaagagaag gagacaatga atctgggaat ctttattatg taaattggct 1265281 agattggaaa gatgaaacag ggcaaactcc tcacttatgc tattcgaaaa aatcatcaga 1265341 tggtgaatac gaagtaagtt gtggcacagg gccgtaaaaa taaattttaa aattgaataa 1265401 gtccaagacg gaaagcctgc ggacactgat cgttttacag agaaatttgt gcttcgatcg 1265461 gtgtccgttt tttttcgcaa ctaaccagat gtctatcgcg attactagct atgaaaggag 1265521 taattagaca tgaaacagtc caaaaagaaa ccatcacaga agcaacatga gcgcttagat 1265581 cgtttctggc aacaaatgat gaacactaac atgcaaacac tcagacgtgg caaaggcggc 1265641 gcttataaac gcagaaagta aaaagggagt ttgaggatga tgaaaaacgg attcgcttat 1265701 aaaaacggaa agcttgtgaa tatcttttgc ggcaaagaag agctctataa cgagttgaaa 1265761 gccttcttgg tcaaaacctt cagtatcaac gtgaaagagg tatcgaggcc ctcaatatat 1265821 cgcagaacaa aaagcaaaca actggaatga cacttactct atttaactat caggagggaa 1265881 agcactatga cagatcaaat gattgcatgg gagattgagg aatggattcg tgattataaa 1265941 ttcatgctgc gggagatcaa aaggctcaac cgtgtattaa acaaagtgga ttttattagc 1266001 acaaagctca ctgcaacata cggggaggaa gcgggcatgc caaggggatc agcaggcgtc 1266061 agtcaggcag aattgcggca gatggaccga agagaaaggc ggcttcacaa atatgaatct 1266121 attgtgcatt acctggacaa tgcaatggaa cacattgaag aagaaaagca ccgaatcgtt 1266181 tacgattgca tgatggaagg catgagctac actgctattg caaaccacct tgattgctcc 1266241 cgggatacca tcagaaagat caaaacagcc ataatcggca acatcgtcaa taaagtcaaa 1266301 gaagccaact ttctgcaata tttgaattcg tttaaatcgg cggtgtaaaa tggggggcag 1266361 gatcggcgcg gcggattatt cctgcgtcac caccaatttc atacaatgag taaaacctcc 1266421 cagtggtaag cgaggatcaa ctcaactggg aggtcttaca tagtgaatcg gtgataaaac 1266481 agcagcagta ttgcgtacat gttaatatcc ccgacaaaat atgttttttt caacagattc 1266541 gttcgacaaa ttttgcaaat tgttaatcga taacttttca ttcccgatat taaaaatggg 1266601 agtgaattgt aaaatgaaaa aacagaaaaa taataaaaag aagaatattg aaaagcgaaa 1266661 tattgaaaag cgaaatattg aagagaagaa taatgaggac ttagaagaac tggaaaatgc 1266721 gatttatact tatcacaaaa aggagctact tgctttcttt cttgaaaaaa ctcgaattgg 1266781 tcatgataag gaagaataca aaaggttcca atctcttctt tataagttgg atattgaatg 1266841 tttagaattt gctatatcga gattttctca tatagatatt atccatgatc attcaaaata 1266901 tgttccagcc tttatccctt tatttgcagc atatctcacc atgttcttta atttttatga 1266961 aaaacattgg ggagctttat cttttgctgc tggtacaatt gctgctattg tttggataat 1267021 tgcagtagaa agaaaacata gaaatcaagc aatttctatt atgaaaatat ttgaacaagt 1267081 caaagagaga aaagtgaaag acagatctaa agactgaaag gagaaaatat gaataaggat 1267141 aaattaaggt atgcaatctt aaaagaaatt tttgaaggta ataccccttt gtcagaaaac 1267201 gatattggag ttactgaaga tcaatttgat gatgctgtga actttttaaa acgcgaaggg 1267261 tatatcattg gggtccatta ttcagatgat agacctcatt tatacaaatt aggacctgaa 1267321 ctgacagaga aaggtgaaaa ctacttgaaa gagaatggaa catggtctaa ggcctataag 1267381 accattaaag agattaaaga ttggattaaa taataagagc atcctgcggg gtgctttttt 1267441 tgttccctgt aaactgcttc cggtaagtct caggatagac aattggcggt taacggcttg 1267501 agcacggtgg tggtttagag ggaatatctt ttccaaaaca acacgaatca gaagggggcg 1267561 gcggtgaatg tagatggccg aaaagcacat tcaggcgtat aaggattacg tcaaaggcat 1267621 gaaatacaag gaccttgccg agaaatacgg ggtgtcagtg aacaccatta aatcgtggaa 1267681 gcagcggcat ggttgggaaa ggaaaaaggg tgcacccatt gaaaaaagtg tgcacacaaa 1267741 aaaaggcggg caaccgggca acaaaaatgc attagggaac aatggcggcg caccacagaa 1267801 gaatcaaaat gctgtgactc acggcttttt ctctaaattc ttgccagaag agacgcttga 1267861 aatcatggaa gagattcagg agcgttcgcc agctgatatg atatgggatc agatacagat 1267921 tcaatatgcg gccattcttc gggcgcaaaa gatcatgttc gtttctgata aggaagaaat 1267981 gatcaaagag ctgaaaaaga aaaggtccct catatctgag gtcagcgaaa ttgaagatgg 1268041 gcttgtcatt agttttagta cgtggtttcg ctacagactt tacagtgaaa caaacaccta 1268101 acacatttca cattgcttca gattgccttc aaacttgata atataacttc taaaccttcc 1268161 tataaaatga aggtttttta tttgatttca atttttaaat cctttacata cagcgattga 1268221 ttaactcgag caatcaatgt cgcagttata tttatttttc aagaaaatgt tataatgaaa 1268281 agccataaaa tgatgggagg gggaatttcg atgcattaca taacggcatg tttaaaaatc 1268341 atcagtgata aagaccttaa tgagataatg aaggaattca aaaaacttga ggaagaaacg 1268401 aacaaagaag agggttgtat tacattccat gcttatccgc ttgagccatc agaacgtaaa 1268461 ataatgcttt gggagatttg ggaaaacgaa gaagctgtga aaatccattt cacaaaaaaa 1268521 cacacaatag acgttcaaaa acaagaatta acggaagtag aatggttaat gaaaagcaat 1268581 gtgaatgatt gaaaggctct ttaaaaagag acattcaatg acttagtatc agccacttgt 1268641 gactaagtag taaattgttg tccaactctt attttttcta tttaatattt tttgagacga 1268701 aaatgttttt ttaagctgat tttaaaatgt attcaaagtc agctctgttt gatttaatgg 1268761 attatattat ttggatagct tgttaccatc ataatggaga tactccttat aaattggagg 1268821 ttaaaataat gagtcattct caagaaaaaa ttgcactaat tacaggagca agcagtcaag 1268881 gggatattgg tacggctatt tgtcgtaagt tagcctcaca gggtatacat atcttcttta 1268941 ctcactggaa ttctgatacg gcctggatag aagaatttca acaagaaatt ttacgtatgg 1269001 gtgtccgctg tgaggcaatg aaaattgatt tatcagatgc acatgctgca ttcacaatac 1269061 atgaaaaaat ttcagataaa ttaggatatc cttccatcct tattaataat gcagctcatt 1269121 ccgcaagtga taattatgta tcgttagatg ctaaatcact tgatgagcat tatgcggtta 1269181 atatgagatc gaattttctt ctttgtgttg aattcgcccg tcggtttaaa aaatctaatt 1269241 taatatcagg aagaatcatc aatatgacat cagggcagga tttaggtcct ttgcctgggg 1269301 agttagcgta tgcagcaact aaaggagcta tttctgcatt tactaggtcg ttatcacaag 1269361 aacttgcacc attgggcatc actgttaacg ccgtaaaccc aggtccaaca gattctacat 1269421 ggatgacaga tgaaataaga aattttcttt cacctaaatt tccaatgggg cgtattggca 1269481 caccagatga tgcagcacga atgattgcct ttcttgcaag tgatgaggct gaatggataa 1269541 ctggacaaat tattcattca gaaggtggat ttattcgggg ctaagctaat gaaacacggt 1269601 atacaccaat gtatgatgta ttcccaaaac taaatctaaa cttgaagcga aaataaggtc 1269661 ccttctcttt ttagaggggg accttatttt attcatgcat gttttgcatc cagaaaatct 1269721 ggcggataaa gattaataaa ccgttacata tacttttccg aatactgcag tacctttaaa 1269781 caaagtaatc gtggctttcc cttttgattt agccgtcact aaaccatttt gatcgacttc 1269841 agcaactttt tggttatcag tccaataacg agtagctgaa ttatttttaa cagaataggt 1269901 ttctccaact tttagaggta aattatagtc ttgaatcttg ataacatgtg taggtgaaat 1269961 agaaatgttc tttacttcag taggtgtgga gtttatttca tgagctgaag ctaccccgct 1270021 gaccgacaga gctaacgcag aaatcgataa agcagaaaca accgtttttt tgaaattcat 1270081 tttgaaacac tcctttaaag ttttttgtct tgcactataa caattcaata aaagtaatta 1270141 ttttccttgt aaataaatgt taataatatg tgaacgatca attgatttga gctaagaata 1270201 ttgtgtgccc tgcacagagt ttgtatttat gatggaaaat tgctgagaga gaatggccat 1270261 ccttaaaatg ttaatagcac acatttgatg ggtattagtt tgttgagcgt gtggaaattt 1270321 tgttacctgc actttatccc cgaagatacc aaatcacttt tcttcatcat gttcttactt 1270381 tcgtactcat acattagaaa atcttcgttc taaataggtg aagaattgga gtatttttat 1270441 gaatttctgc tgaatataca ttacatagca aactcaaaga gtataaaaat cgcttttttc 1270501 cggaagcttc ggtaaaaaac gaaacttttg tctctatgat tttgttttat aatgtaaacg 1270561 gtttcttata tagtatactt atactatcaa tttgctcaag tagatactga caggaaggat 1270621 agaaaaacag atggaataca taaatacaag acaaaaagag attttgtatc tgttgttatc 1270681 tgaacctgat gactatttag ttgtgcaaga tttcgcagat agggtacagt gttctgaaaa 1270741 aacaatccgg aatgatttga aagtgatcga ggattatctc aatgagcatt ctcatgcaca 1270801 gcttattcga aaaccagggt tgggcgttta tttacatata gaagaacagg aaaggacctg 1270861 gctaagccaa caattacata ctgaacattt ttcttctagg cagcggagcg ataaggaaag 1270921 aatgctgcac attgcttatg acttattaat gaatccgaag cctgtttccg caaaagacat 1270981 tgccgctcgg cattttgtca atcgatcttc cattaaaaag gatttatacg cagtagaaga 1271041 gtggctgaag cgttttgatc tcacactggt ttctaggcag cggcttggat taaaggttga 1271101 agggaacgaa agaaataaaa gaaaggcatt ggcaagaata tctgatttga ttcacaatac 1271161 agcgtttacc agccaattta ttaaaagtaa gtttttacat tatgaagtag actttgtgac 1271221 gaaagaaatc aaatcactac aaaaaaagca ttccctctat ttcacagacg aaacgtttga 1271281 aagtttgttg ctgcatacat tgttaatggt ccgccgcatc aaaatgaagc agccgatttc 1271341 attgtcccca aaagaaatgg cggcagtaaa aaagaagaaa gaatatcaat ggacatttgc 1271401 ttgtttacag cggcttgaac cggtttttgc aattcgcttc cctgaagaag aagccgtgta 1271461 cttaacatta catatattgg gcggtaaggt tcgttatcca ttgcagacag aagagaacct 1271521 tgaaaatgct gtgcttccta aggttgtagg gcatttaatc aatcgtgttt cagagctgaa 1271581 aatgatggat tttcacaagg atcaggattt gatcaatggt ttgaacattc atctcaatac 1271641 tgtgctacaa cggctgagct acgatctttc tgtagcaaat cctatgctca atgacatcaa 1271701 aaagatgtac ccttatttgt tccacctcat cattgatgtt ttggaagaca tcaatcaaac 1271761 ttttgatctt catattcctg aggaagaggc agcatatttg acattgcatt ttcaggcagc 1271821 gatcgaacgg atgcagggca gcagcgagac acataaaaag gcggttatcg tctgccacat 1271881 ggggattggg atgtcacaat tgctgcggac aaaaattgaa cggaaatatc accaaatcgc 1271941 tgtaatggct tgtattgcaa aggccgattt aaaggattat atcaaaaagc atgaggatat 1272001 tgatcttgtc atatccacca ttgcgctgga gaatataacg gttccccata ttgttgtgtc 1272061 tccgctttta gagcctggcg aagagaagaa attaagtgcg tttatacgtc agctgggcga 1272121 atcacaccgc caaaaacaaa aaacgtttca gatgctgaac aatacgactc cttttttggt 1272181 ttttttgcag caggaggcgg agcatcgcta caagttaatc gaacagctgg cgacagcttt 1272241 gtttgagaaa ggctatgttg ataaggacta tgcggttcat gcggtgatga gggaaaaaat 1272301 gtcggctaca aatattgggt caggcattgc cattcctcat gcaaacgcta aatttattaa 1272361 acaatcagca atcgcgattg ccacattaaa ggagccgctt gaatggggaa atgaaaaagt 1272421 ttcgctcgtt tttatgctgg ctgtcaaaca cgaggatcaa actatgacaa agcagctgtt 1272481 tagcgagctt tcatatctta gcgagcagcc ggccttcgtc cagaagctga cgaaagaaac 1272541 caatgtcatg acatttttat ctcatttgga ttattaaaag cagggattat tccttgcttt 1272601 ttttgttata gggaaaaatg cctttattac cggaacctat ggtaaaaaaa gcgattttaa 1272661 tgagctgatt tcggtataca gttgagacaa gatcttatta ttcacacttt aaaggaggtt 1272721 tcctatgaaa ctgttagcga ttacatcttg tccgaatgga atcgcccata cgtatatggc 1272781 agcagaaaat ctgcaaaaag ctgctgacag actgggcgtt agcatcaaag ttgagaccca 1272841 gggagggatt ggtgttgaaa ataagctaac cgaagaggaa attcgcgaag cggacgcaat 1272901 cattattgct gcagaccgtt cggtaaacaa agaccggttt ataggcaaaa aactgctgtc 1272961 tgtgggggta caggacggta tccgcaaacc ggaagaattg attcaaaaag ctcttaacgg 1273021 ggatataccg gtctatcgtt ccgctacaaa atcggaatcc ggtaatcatc aggagaagaa 1273081 acaaaatcca atttaccgtc atttaatgaa cggcgtttca tttatggttc ctttcattgt 1273141 tgtcggcgga ttattgatag cggttgcatt aacgcttgga ggggagaaaa cacctaaagg 1273201 cttagttatt ccggatgatt ccttctggaa aacgattgaa cagatcggca gtgcttcatt 1273261 ttcatttatg attccgattt tagccggcta tatcgcctat agcatcgctg ataaaccggg 1273321 gcttgtgcca ggtatgatcg gcggttatat tgcggcgact ggaagttttt atgacagcgc 1273381 aagcggcgcc ggattcctcg gggggattat tgccgggttt ttggccggat acgcggcact 1273441 ttggatcaaa aaattaaaag ttccaaaagc catccagccg attatgccga ttattattat 1273501 tccggtgttt gcatcactga ttgtaggttt agcgtttgtg tttttgatcg gcgcgcctgt 1273561 agctcaaatt ttcgcctctt taacagtttg gctggcgggg atgaaagggt cgagctcgat 1273621 ccttctggca ttgattttag gggcgatgat ctcatttgat atgggcggtc ccgtaaataa 1273681 ggtggcgttt ctgtttggat cggcaatgat tggagaagga aattatgaaa ttatgggacc 1273741 aattgctgtc gccatttgta tccccccgat tggccttggc attgcgacgt ttttaggaaa 1273801 aagaaaattc gaggcatctc aaagagaaat ggggaaagcg gcatttacga tggggctctt 1273861 cggcattact gaaggagcga ttccatttgc ggcgcaggac cctctgcgcg ttattccaag 1273921 tattatggca ggctcaatga caggttctgt gatagccatg attggcaatg tgggagacag 1273981 agtggcgcac ggcggaccta tcgttgcagt gcttggcgca gttgatcatg tcttgatgtt 1274041 ttttattgct gtgattgcag gatctcttgt cactgctctg ttcgtcaatg tactaaaaaa 1274101 ggatattacg gcgtctcctg tgctcagtga aactgcaccg acctccgcgc caagtgaagc 1274161 tgcggcagca aatgaaataa agcagccaat tcaaagccaa aaagctgaga tgtcggaatt 1274221 taaaaaactg acagacatta tcagcccgga attaattgaa ccaaatttat cgggggaaac 1274281 gagtgatgac atcatagatg aattgattca gaaattgtca cgaagaggtg cgctgctttc 1274341 agagagcggg tttaaacaag ccattttgaa tcgtgaacaa cagggaacaa cggcgattgg 1274401 catgaatatc gcgattccgc acggaaagtc tgaggcggtc agggagccga gtgttgcctt 1274461 tgggatcaaa cgatcaggcg ttgattggaa tagcctggat ggatcagaag ctaaattaat 1274521 ctttatgatt gctgtaccga aagagagcgg gggaaaccag catctcaaaa tactgcagat 1274581 gctatctcga aagctaatgg atgacaatta tagggagcgg ctgctctccg tgcaaacaac 1274641 agaagaagca tacaagctgc tagaagaaat cgaataaagc gggggatttt catgacgact 1274701 gaaccgttat ttttcaagcc tgttttcaaa gaaagaattt ggggcgggac cgctttagct 1274761 gattttggct ataccattcc gtcacaacga acaggggagt gctgggcttt tgccgcgcat 1274821 caaaatggtc aaagcgttgt tcaaaacgga atgtataagg ggttcacgct cagcgaatta 1274881 tgggaacatc acagacattt attcggacag cttgaagggg accgtttccc tctgcttaca 1274941 aaaatattag atgctgacca ggacttatct gttcaggtgc atccgaatga tgaatatgcc 1275001 aacatacatg aaaacggtga gcttggaaaa acagaatgct ggtacattat tgattgccaa 1275061 aaagatgccg agattattta tggccacaat gcaacaacaa aggaagaact aactaccatg 1275121 atagagcgtg gagaatggga tgagctcttg cgccgtgtaa aggtaaagcc gggggatttt 1275181 ttctatgtgc caagcggtac tgttcatgcg attggaaaag gaattcttgc tttggagacg 1275241 cagcagaact cagacacaac ctacagatta tatgattatg accgaaaaga tgcagaaggc 1275301 aagctgcgcg agcttcatct gaaaaagagc attgaagtga tagaggtccc gtctattcca 1275361 gaacggcata cagttcacca tgaacaaatt gaggatttgc ttacaacgac attgattgaa 1275421 tgcgcttact tttcggtggg gaaatggaac ttatcaggat cagcaagctt aaagcagcaa 1275481 aaaccattcc ttcttatcag tgtgattgaa ggggagggcc gtatgatctc tggtgagtat 1275541 gtctatcctt tcaaaaaagg agatcatatg ttgctgcctt acggtcttgg agaatttaaa 1275601 ctcgaaggat atgcagaatg tatcgtctcc catctgtaac atggcagggc ttgagaaata 1275661 aatttgcgag tgaagacgcc tattctccag caatgatcta aataaaataa gagtttaata 1275721 gttggagaag aaatgttaca ctcttttctg tatatggtaa agaatgaaaa aacacgattc 1275781 ggttggtagt ccggatgcat gattgagaat gtcagtaacc ttcccctcct cgggatgtcc 1275841 atcattcttt aatatctttt atgaggaggg aatcgttatg aaattaacga tttactacga 1275901 tggtcagttt tgggtaggcg ttgttgaagt tgtggacaat ggaaagctaa gagcctttcg 1275961 tcatcttttt ggcaaagagc cgagggattc tgaagtatta gagtttgttc ataaccaact 1276021 tttgaatatg atggcccaag ctgagcagga aggagtgcgt ttacaaggca ggcgtcaaaa 1276081 aaagatcaat ccaaaaagat tgcagcgcca ggtttcaaaa gagttgaaaa acgccggagt 1276141 aacttctaaa gctcaagagg cgataaagct agagcttgaa gcaagaaagc aaaagaaaaa 1276201 acaaataatg aaagaacaac gagaacatgt aaaagagcaa aggtatatgc tcaaaaagca 1276261 aaaagcgaaa aagaagcaca gaggtaaata atccaaacaa aagcaggcgc agtgcctgct 1276321 tttgtaatta aggactctac tttgtaacat atatccaatg tttatactcc gctgatttat 1276381 gattcaatat aaaccctaac ttctccaagg ttttttgtga gcctagatta tcatgttcgc 1276441 atcttgcggt gatccgggat actgtttctc ggcttaatgc ccagtttatt agtttttggg 1276501 cggcttccac acaataacct ttgcggcgat gacttttatt tgttgcaaaa ccgatttcaa 1276561 tcatgccatt ttcgtctggg tcacctaaaa atccagttcc cccaacaatt tcataattgt 1276621 ccttctttac aataatccat gaatcaaatc cttttgttcc attgtttttg actaaaatct 1276681 cgcggaaata aggtatcgct tcaaaaaaat cagaatttgg ccattcacca tttgtttcat 1276741 agcctaattc tttgatagcc tgatgatctt gtttagacgc ggcgtcaaga aggggaatat 1276801 caatcgtttg taatcgtaat cgattcgttt caaggagaac catatattta atcctctttt 1276861 ctttttactg ggaataatga taacatataa caattttctc tggtaccttg gcagtagaga 1276921 aagatgaaaa aattgagggg gattgaaaga gtgacaggtg agagtttgcc cagaccaaaa 1276981 acgggtagga aaatgctgat gttaatgtgt ccctacccgt ttttctgttc ctgaatgcag 1277041 ggtttctgat aacatgttgt gctacctttt cgcaatcaaa taaagcgata tggctctttg 1277101 ggtttgcaca ggattatgaa tgataatgac ccattggttt cttcgtcttg gaaagcttgc 1277161 taccgcatac aatggagcag tatcgcgcgg agtgaaccca ccatttatca cgttgatatc 1277221 tcttccttca agatgacaaa ctaagtattc acctggattg atgacctgtt ggttcgtcca 1277281 tgcgtaagaa taaaagccgt ctccaagatc ttcggtggaa gatgggggga caaagccatc 1277341 tacagtcaat gtgatttctc ttcttcgctg tctttctgaa aagtctggac ttctttgagg 1277401 gttatgagta tgtgaaaagt aaggaattaa cgcagggcca taaaagtaat gatacaaagc 1277461 aaccactcct ttattttcca ttcatacaaa ttgtatgtgg gagttatttg ttcattcctg 1277521 ttttgttcca tgtagactaa taatgggcta taggcgtcca aggaaatcaa tttgtccttc 1277581 cgttgattca atgctagtaa ccttgaaaat gcaggttagg atgatagaat ttacatatta 1277641 ctgcaagaag ttagacatac atcattttga tagtgggtga aaacaatggc gaaaaaaatg 1277701 gcaaaaacaa atgcggttcg tctgatagaa cagcagaaca tctcttatga ggtattaggg 1277761 tataaaacag acggccagcc ggtagatggc atctctgttg cggaaaaaat cggttattct 1277821 ttgaaatatg tatataaaac gttggttgca gcagcaggaa caaatcatta ttatgtcttt 1277881 gttgtacccg ttgcagaaga gttagatgta aaaaaggcag caaaggtgac aggggaaaag 1277941 aaaatagaaa tgattgcaat gaaggagctg ttagcggtaa ctggctatct tcgcggcggc 1278001 tgctcgccaa ttggcatgaa aaaattgttc ccgacctata ttgatgcatc tgcagaaacg 1278061 cttgatttta ttattgtcag tgcagggaaa atcggtatgc agctaaagtt ggcgccacaa 1278121 gatttagcca gatcatgtga tgccgcattt gcagaaattg tatagatgca gatatagggg 1278181 aacgaaaaag cttagtcata tcgattaagc tttttccgca tccctttcaa atatgatttc 1278241 aaaataagca gctgccccat acccatctat actgggagcg aaaatctgaa cgaatctcca 1278301 gcctcttttc gcataatcat ggatgatttg ctggtagtct tctttaggcc ttcttctcat 1278361 cgtactcagc tcaactctta cgaattcata ttctttcatc gtttgatccc tcctattaag 1278421 gtatacgtaa aatggagcga gaagttccga aaacctaggt taaggtcgga aagtatattt 1278481 cactcactaa acaaatccat ttatgcctga tgcctgcatg catctgggaa gagttaaggg 1278541 gctataaaaa cgaattttac cgggtcagca gtccaaatga atctcttgct tattgcattt 1278601 gactgagtat ataagtaaaa aaagagcggc cagaacatat aagaaggaga tgatcattaa 1278661 cgcactcata acagggtagt gtttagcgga gtagatgaaa aaatcaagct gtgaaatttg 1278721 tttggggctg ctgacggcat caattccatt aagcagtttt gagagtttag cagtatagtt 1278781 ccaatcaaat cgatctgaaa caagctcgct tccttgatac caattaacag cagctaaaaa 1278841 cagaaatacc ataatagaaa atccaagctg aacaactaaa aatattccct tcacttttgt 1278901 atgacctcca aatctatgaa tatgggaaaa tcaaacaata tattaccacc gtatgggtta 1278961 ttcttgcaat ttcacttcca tacaactcaa acgcaagtct atttttttgt ttgtttttgg 1279021 cttataatac ctgatgatgg aaaaagagtg cgggtttata gattagagaa acaaatgtat 1279081 ttcttagcat tttttatttg tggagagagt atagaagcat tcgattagat ctgctttttc 1279141 acagaaacgg ttttcatctg tttgcctgag ctttacaatt ggctggcaaa aaaacaatga 1279201 tttctttcaa tcaaaacatg caacgatgcg acacatttta tatcttgatg acttatttca 1279261 ttgcctttaa gtcatcctat cgagaaagcg atggtatttt atgaacaaag aaaccctaaa 1279321 aaacatactc atgatttttt caatatgcgc aacactccga gaaaccgatg gtatgcgcat 1279381 agctgatagc tggattttga gtgagattat acgatttttg atttgcatgg ttgtgttttt 1279441 tgccatgaca tttctattag atgctgtttt tccaaacaaa aaagagtcac attaatgtgt 1279501 ggctcttttt gcatcatctg atcagaaaca tcataaatga atcgatcatc atgatgaaga 1279561 acagcaagca aaaataaata agcgagtaga caaacatatc ctttgcccac ttcacgtcat 1279621 cgtctgtttt gaatcctttg atgctttttt tgatccatat gcctccgaga accaaggcgg 1279681 ctaagaaata aaatgggctt atatggccgg tgccgagaga gaaaggaaat aatagcgtga 1279741 ccggcaccag gacggcaata tattgcatca tttttatttt tgttacatga ttgcctttga 1279801 ctactggcaa gagcggaacg ccagcagcgc gatattcctc tttgcgtctt atcccaatcg 1279861 cccaaaaatg cggcggctgc cacagaaaca taatcgtgta caacagcact gctgtcatac 1279921 tgaagtcacc ggttacggca caatacccca tcaatggcgg cgcagctcct gggaagctcc 1279981 cgacaaatgt gctccacaca gacgttcgtt tcacccatac cgtatagatg atcgcataaa 1280041 aaataaaggc ggccagtccg agaaaggccg ttaatggatt gagggaataa agcatggcaa 1280101 gacctgcgat tcctaaaaca gagccatatg ttaagatcat ggctggcggc attttccctg 1280161 tgaccgaggc cctgctgcga gttcgtgcca tttttgcgtc catatgccga tcaaaatagt 1280221 tgttatagac agtgccggaa gccatcacaa acgcggttcc caacattgct gttaccattg 1280281 tcatcaaaaa agccaagccg gttaacgttt tttctgcgct tgcaaacgcg atccaaaacc 1280341 cgccgaaggc tgctatcgag tttgatatga taatgcccgg ctttgcaagt ttgataaaat 1280401 cgtaaatggt tacccggttc gaagctttta tgtattttgt ttcagatatg gctgcagaat 1280461 ctcttgtatt ctccaaaaat agacgcctcc cccaaaactg catgcttttg ttatcgtaac 1280521 aagaggggga cagaatcaca attatttccc atatttgtca tgatattgtc atttttaaaa 1280581 caaaaaaatg gggagctgga ctgcccccat tttgatatgt ggcgactagt aaccgtaacc 1280641 tcccccatat cctccgccat aacctccgcc gtaaccgtac caagggtagt aaggcggtcg 1280701 cgggcgcggg tagtaataag gcgggcgcgg ataaaacggg tagaacggat aatacggtct 1280761 tggataataa taaggcggat aaaatggcgg tctcggacgc ggataataat aaggctgtct 1280821 ttcatcataa ggggtaattt gttcaaatga ctgttcattc aaagggtaat ccaagaggaa 1280881 aacctcccta gcttttttta ttccttttac catattcctg atgcttaagt tgggtgtatg 1280941 tacattcatg aaattcggtt ttttttatga tgaaattcct taaaaaggat tgacatgaac 1281001 ttctaaatct catagtatta caaatgtgaa ataaatgtta ctacaatgtt acaaaaacat 1281061 ttctaaatag atacagttcc aactgatgaa gagtaaatcg aaatggctac gaaagaagga 1281121 gtttttgttg ttggcaaaaa gaatcaaatg gtttcatgta ttaatagcag ttgtatgtgt 1281181 ggtgggcctt atcggctttt tccataatca ttcattgaaa aaagaaacgg tcatgaataa 1281241 agtaagaact gattctcaat atgggaatgt tgagatcgca acgcttgtga atgacgggaa 1281301 aacttttaat tacgcggtaa actatcctgt tttcaaaaat gaaaaaatgg attcggcatt 1281361 aaaaagattc gcagaaaaag aggttcgtca atttcaaaag gaaacaaagg acgttgacca 1281421 agagcatacg acaaaacgca acgaattaaa tgttgattat aaaattgtcc attatgccaa 1281481 acagacagtg gcgattgtat ttaatgaata taaatacatc ggcggggcac acgggcaaac 1281541 cgtgaaaaaa acgtttaact atgattttag taaacaagcg tttctttcca ttgatgatat 1281601 tttcaaagag gacgctgact acttacataa gctttcgtta atcgcttatc acgagctgaa 1281661 aaagaataag gacattgccg cggacgatgc actgttaaag gaagggacgg ctccgaaaaa 1281721 agaaaatttc agccgctttg ccatcaagga ggattatatc gaactttact ttgacacata 1281781 tcaggttgca gcaggctatc ttggagagca atcgattgcc attaagaaaa gtcttttgaa 1281841 agacattctg aaagaacaat atattgataa agcaaaaaat aaaaataaaa tcaaagaaca 1281901 aaagccgaag catgaagtga tttctttacc caaagaggaa acagttgatc caaatcaaaa 1281961 agtcattgcg cttactttcg acgacggccc gaatcctgcg acaacaaatc agattctaga 1282021 ctccttgaag aaatataagg gtcatgccac gttttttgtt ttggggagca gagttcaata 1282081 ttatccggaa acgctaataa gaatgctgaa agaaggaaat gaggttggga accattcatg 1282141 gagccatccg cttctcacaa ggctttcagt gaaagaagcg ttaaagcaga tcaatgatac 1282201 gcaagacatc attgaaaaaa taagcggata tcgtccgacg cttgtaagac ccccatacgg 1282261 cggcattaat gatgaactgc ggagtcaaat gaaaatggat gttgcgttat gggatgttga 1282321 cccggaagat tggaaagacc gtaacaaaaa aacaattgtt gaccgtgtca tgaatcaggc 1282381 gggagatgga agaaccattt tgattcacga tatttaccgc acctctgctg atgcggccga 1282441 tgaaattata aaaaagctca ccgatcaagg ctatcaattg gtgacagttt ctcagcttga 1282501 agaggttaaa aaacaaagag aagcgaaata aattagaaaa ggctgtccgt acggacagcc 1282561 ttttttctat ttaataagag cctgtggtgg cccaaacatt taagtttggt cctgaatact 1282621 tgccgaaagc gtaagaagtc cttggatcta aatcatatac catcggtgta tagcaagact 1282681 tttggccggc caccgctttt ccattgccgc ctgcagaatc acaattatat ctttttccgt 1282741 ctgtgttccg ggtaatctcc gcatttgctt catagccaga cgtcaatgta ttattcatcg 1282801 tgatttttgc ccaagccgtt ttacatgtac tgctgaattt aagctcgact actccgatga 1282861 cttgattgct ggcattcact aagtttgagg atttttttgt agagccgctg gacgcacaat 1282921 cattgtaata agggcttttt ccatcgtagg catgggtttc cgccttggcg ggtgcacctt 1282981 tgacggcaaa aacaaatact actgcgaata acaccaatga agccttcata aacagtcttt 1283041 tcaatttatg acctccttaa tatggcaaac aataaatcat atggaggaac aatcaaaaca 1283101 tgcatgcttt tttgtgaaca ataaaggcgg ccgggaggat ggagttcttg gccgcctctg 1283161 gtatgaggtt atgcttttac atcaatggtt tgtccgagag ttggatgttg aatcatcttt 1283221 aaggtttgat cggcattttg ctgggcggtg tccagccttt ttttcgttaa agcaatattt 1283281 acattctggg caagggatgc ttgatgcatc gcaaccgata aagcaggaat atccatggtt 1283341 ccacctccta tgccttacct atcggcgggt ttgtatgatt ttacagtgaa aaatggctta 1283401 atttctcttg ttgaccctta cgctgcggca tatcgtatgt ttttgacaag gagggaatca 1283461 ggatgaatct agtaatggaa aagacctttg agcaatacga aaagctgttt tcaatggaag 1283521 aacagaaaag agaagatgta tttcggtata cgatgatgag gccgtttgaa aagatgtgga 1283581 ccgccatcca agttccgctg aaagcgaagg agccaaacgg ctatgatgtg atcatggctg 1283641 cgaaaatgct gggctatttg gatgtccgtg atgctgaaag cggccagaaa gcactacaaa 1283701 tactgaaaga atcacatgtt tcagagacag ctgaatctgc acttcggcaa tgcatatttt 1283761 ttgctgagcg cgaacagctg cgggtgaatg caaaggagat caaattcggc ctttatatcg 1283821 ctgatccaaa taagcttcag ctgcaaaaag gctactgcgg gtttggcggg ataccgggct 1283881 ttattcatgt atggattaat ccgaacagtt ataacctgcc aaggattcct tccattattg 1283941 ctcatgagtt tcatcataat gtgcggtttt cgtatataga ttttcatcat ggctctgtaa 1284001 gtgtcgggga ttatcttgtg attgaaggat tggcggaatc attcgccaga gagctgtttg 1284061 gtacggaacg attgggccct tgggtaactc gttttgatca tgaagacttg caatattcca 1284121 ttgatgtgat taatgaggtg ctggatgtga aaggattttc ggaagtcagc cgttatatgt 1284181 ttggtgatcc aattgctaac gaccaaggct ttaagcctgc aggtttatcg gcttttgcgg 1284241 gttatgcagt tggctatcat gccgttcagt catttatgaa tcaacatcat atcacgataa 1284301 gcgaggccac acgtttggat gcgaagacca ttatttctca atgcggtctg ttttctacat 1284361 gaaaaaagcg tcacatacag cggcgctttt tgattcccaa aaccagcagt tctatggcgg 1284421 cacaggcggc aattccgatt gtatatgctt cgatatcgct ccataaaaaa ccgtacccta 1284481 gtacaagccc gccaagagaa gtatctctaa tctggtcgat ccattcggca tgatagagct 1284541 ggctgaattc aatgacaaaa cagaaagaaa gactgataat gcccgttatc attgtcttca 1284601 gcttccgaaa tagaaatccg catcccgtga agatcatggc ggcccacaac gagtctccca 1284661 gataagtatt gagggtatca ggaagaacac tggagaatgc tctggatcca agccccagcc 1284721 caatgatcag tatggtgaaa actgcatata tccaacgatt tcgcttcatt gcgaattgat 1284781 accccgtctc tgcttcatct ccctgtattg taaggaatat agcttttatt tgtccactaa 1284841 aaaagcggct gaatagccgc gtagggtgtt tattttgctt ttaggtttac atggtcggct 1284901 gtctgatccg tgcctattac aaaatggagt tcatagcggc ctgtatcata tacataatcg 1284961 atttcatcgg taaacgggac ggttaacacc cgatttactg gtcctaattg cttctgcagc 1285021 acttccggcg taactccgcc taaattcagc tgccgttcca caccggttcc aaagtagcgg 1285081 atttctgaaa ttgtcatgtc tttatgatag gaaaatccgt agcccggctg tcccatattc 1285141 cagtgatata aatcaaatcg attgtctccc ccgactggtc tttccggttc cccaaacgca 1285201 gcgtggacat ccccttttgt gcttttgtta atggtaaggc cttgcgcctg ctgaggcatt 1285261 tcccctttat aggcggtgtt atagaggttt ttgacaagct cagcggctga ttgattcgtg 1285321 ttttctgaga gtgtgtttgt ttgagctgcg gcctttgccg gtgctgaaaa ggacgcagcc 1285381 ccaaagccgg taaaacagct tgttactgct gctgccgcgg ttatagcaga cattgtcttt 1285441 ttcatgttaa tccctcctaa ttgatctacc attccgtttc cccgtgtttt tgcaacgaaa 1285501 catgtgagtg cgctttgtat gttttattga gttgttgtaa gggaactgaa ataggtaatt 1285561 cggtatataa agcaagaaag gggaatggag atggctggca agaaaacaat cacaataaac 1285621 ggcgttgaaa tggaagcgtc cgaggaacag acggtgctgc agcttttgaa taacagctcg 1285681 attgaagtgc cgcaagtttg ctatcatcca agcttagggc cgattgagac atgtgatacg 1285741 tgcatcgtca gcatcaatgg tgagctgaag aggtcgtgct ccgctgaatt aaaggatggg 1285801 gatgtcattg atacgctctc acctgacgtg aaaaaagcgc aggtcatcgg gatggacaag 1285861 attttatata atcatgagct ttattgtaca gtttgcgatt acaacaatgg gggatgcgaa 1285921 atacataata cggtgaagga aatgaaaatc aatcaccaaa gcattccgtt tgatcacaag 1285981 ccataccata aggatgaatc ccatccgttt tatcggtatg atccagatca atgtatattg 1286041 tgcggacgct gtgttgaggc atgccaagac gttcaggtaa ctgaaacgct gaccattgac 1286101 tgggagcgga aacgcccgcg cgtcatttgg gataacgacg tgccgatcaa tgagtcgtca 1286161 tgtgtgtcat gcggccattg ttcaacggtc tgtccgtgca acgcgatgat ggaaaaagga 1286221 atggaagggg aagccggata tttaacaggc atcaataacg aaacgctgcg accgatgatc 1286281 gagatcacga aaggcgtaga gacaggctac ggctcgattc tcgcgatttc tgatatggaa 1286341 tcggccatgc gtgatgaacg aatcaaaaaa acgaaaaccg tctgcacgta ttgcggcgtc 1286401 ggctgcagct ttgatgtctg gacaaagggc agagacattc tgaaagtaga gccgcaggag 1286461 gaagcgcctg ccaacggcat ttctacttgt gtgaaaggca agttcggctg ggatttcgtt 1286521 aacagcgaag aacgcctgac aaagccgctg atccgtgaag gcgatcattt ccgtgaagca 1286581 gagtgggagg aggcgttatt gctgatcgcc agcaagttca ctgaattaaa agaggcgttt 1286641 ggcccggatt ctctcgcttt tattacatct tctaaatgta caaatgaaga atcctatctt 1286701 atgcaaaagc tggccagagg ggtcattggc acaaataatg tggacaactg ctctcgctat 1286761 tgccaatctc ctgcgactgc cggcctgttc cggacagtcg gctatggcgg tgattcagga 1286821 tcaattacag atatcgcgca agcggacctt gttttgatta tcggttcgaa cacgtctgag 1286881 tcgcatccag tcttatccac tcggattaaa cgggctcata agctgagagg gcagaaagtg 1286941 atcgtcgcgg atatcagaaa gcacgaaatg gcagagcgct cagatttatt tgtccagccg 1287001 cgtgccggat cggatatcgt ctggctgaat gcgatcgcca aatatttaat agaaaacggc 1287061 aaggccgatg aacgattttt gagagaaaga gtgaacggac gggatgaata tgtaaaaagc 1287121 ctcgcgccgt acacacttga atatgctgag gagaaaaccg ggattgatca agaaaccctt 1287181 atccaaatgg cagagatgat cgggcaagct gacagtgtgt gcgcattgtg ggcgatgggc 1287241 gtgacacagc atattggagg aagcgacacg agcacggcga tctctaatct gctgcttgtg 1287301 acaggaaact acggaaaacc gggagcaggt tcttacccat tgcgcggcca taacaacgtg 1287361 cagggagcaa gtgactttgg gagtatgcct gacagactac cgggctatga aaaagtgacg 1287421 gacgaacaag tccgccaaaa atacgagcgt gtgtggggtg tgccgctgcc gaaggagccg 1287481 ggtatgacca accacgaaat gattgaaaaa atccattccg gacagttgaa agcgatgtat 1287541 gtaaaaggtg aagaaatggg ccttgtcgac tccaatatca atcatgtaca cgctgcatat 1287601 gaaaagcttg atttctttgt ggtgcaggac attttccttt cacgtacagc ggagtttgct 1287661 gatgtggttc ttcctgcgag cccgagcctt gaaaaagaag gaacgtttac aaacacagaa 1287721 cgccggattc agcgtttgta tcaggtattt gaaccgctgg gtgaatcaaa gccggattgg 1287781 cagattatta tggaggttgc caataagctt ggcgccggct ggctctatga gcatcctgca 1287841 gacattatgg aggaagcagc caagctgtcg ccgatttatg ccggtgtcac ctatgaacgt 1287901 cttgagggct ataattccct gcaatggcct gtaaacgctg atggaaagga ttcgccttta 1287961 ctctttacag agcgcttccc tttcccagac ggcaaggcca ttctctaccc tgtccagtgg 1288021 acagagccta aggaattcgg tgaggaatat gatatccatg tcaacaatgg gcggctcttg 1288081 gagcacttcc acgaagggaa cctgacttac aaatcaaaag ggatttcgga gaaaacaccg 1288141 gaagtgttct tagaaatttc tcctgagctt gcggcagaac gagggattca ggacggaacc 1288201 ctcgtcagac tcacatcgcc tttcggaaat gtcaaagtga agtgcctgat tactgatcga 1288261 gtcaaaggga aggaagtata tctgccaatg aacgattcag gggaagcggc gatcaacctg 1288321 ttaacaggca gccatgccga taaggatacc gatacgcctg cttacaaaga aacatcggcc 1288381 aagatggaaa ttttgaagca cgacggaatc agcccgctgc ctaagatcaa ccaccgcaac 1288441 ggcaatccgc agccgcaaat cggtgtgcag gttcataaga aatgggcgcg gaaggattat 1288501 attttccctg gtgacgctgt gaaaaggggg atgggccata atggctaaag cgattaaacg 1288561 aatccaaaaa atcgaggtaa cagaagagga tcagcgaaag cgtgatttgc gggaaattga 1288621 agatgctcta attgaccaca aagaagcgat tctcgaaaca ttgcatatgc tgggccatat 1288681 gaacgagcgc ggggtcctgc cgttgctccg cggccttttt ggtcaagggg ataaagttct 1288741 tgatatcctg gtgaaaaagg cagatacaga ggaaacagcc aatacgctga aaaatctgct 1288801 tcttctgttt ggaacactcg gcatgctgga cgtgaagcag ctggagcctc tcattttgaa 1288861 agtgaatgcg ggtgtggcaa gcgctgtaga gcagaaaaac agtgaagaaa agacaggtta 1288921 ttttgatatt atccgctcgc taaaagaccc ggaaatcaac aaatcaatta cactgctctt 1288981 ttccttttta aaaggaatgg gacaagatac aaaggagctg gaacgcacga cgcagcctcc 1289041 ggaacaccaa aaacatcatc aggaaccccg agagaaaaga ggaatgaata agcgagattg 1289101 acctcccacc cgagcggctt cagccagctc gggttttttg atgaaaaggt ctaatggact 1289161 agtaaaaaat attcaaatac taggaagaag taagattgtg atgaatgaga tagaaataat 1289221 cgttactttc ttacctgtta agaaaaggga aaatctgatt ataatagaaa tcgattactt 1289281 tagatggggg aacaatcatg aaaaaagtct tattactatt atttgtcttg acgatcgggt 1289341 tagcgctttc tgcgtgcagc caatcgagcg atgcgtcaga gaaggaaaaa ccgaaagaga 1289401 aaaaatcgca agaagagctt gaaaaggaac ttgataagga attgaaaaaa ggcggtgagc 1289461 cgaagaccaa aaaagatgat caaatacata aaataggaga aacatttaaa gcaggacata 1289521 cgaattttac agtgaataaa gttgatagag tgcaaaaagg tgaatatatg aatgttggcg 1289581 gagctgtaaa tgaggagaca aaaacaataa aagatgatga ggaacggctt attatagaag 1289641 ttacgatgga aaatataggg gaagattcaa taagctacaa ttttatcggg tttgatttaa 1289701 gagataagaa tgatcaatca gtgcggcctg ttttttctat agaagagaag ggcagaatcc 1289761 ttatgggagg aacactagta tcggggaaaa aggttacagg tgtactcagt tatgtcatcc 1289821 ctaaaggaga acagaaacat tacacactgg tatataatcc gtttttagct gatacaaata 1289881 gcagtaatac agaagagaga gtaaaggacg atattgatta cttggtgaag ttagattaga 1289941 tgctaattta cagttgcacg tttttcatct gtggaaaacg tgcatttttt atagcgaaac 1290001 ttgacttgaa aggatgagtg ataaaagtgc aaaccaaatg gctggaacgg gcacagcgga 1290061 ttcgggcgat cgcccaagcg gggcttgctt tttccaagga tgtgtacgac agggagaggt 1290121 acgaagagct aatgaagctt agcgcggaaa tgatggcgga ttactcggag aaggacattg 1290181 aagttatcac tgatttatgg caaggcgaga agggctatcc aacaccgaaa gcggatgttc 1290241 gcggcgctgt attcagagag aatcagattt tgcttgtccg ggagaagcat gatgagctgt 1290301 ggtcgctgcc gggcggattt tgcgagattg gtttatcgcc ggctgaaaac gttgtcaagg 1290361 aaatcaaaga agagtcgggg tacgatacag agccgtctcg attgctggcc gtgctagaca 1290421 gccataaaca ctctcatccc cctcagcctt atcactatta taaaatcttc atcgcatgca 1290481 gcatgacgga cgggcagggg gaaacaggga tcgagacgaa tcatgccgct ttttttccgg 1290541 aagacagact cccgccgctt tctcctaaac gaaacacacc ctcacagctt agcatgctgt 1290601 ttgacttttt gcgccatccg gacaagaaaa cgatatttga ctaaaaaaga aagagcctgt 1290661 gggctctttc ttttttataa tgtaatgtgt ttttcgttgg cgagtttcag aagggtcaaa 1290721 atagaatcgg cttgtttatg gccgagtttt tgctttaatt tgttttcttc aactaatcgg 1290781 ctgccataaa ttttgacgga ggctttgtcg acgacagtat gccagttttc ctgttttttt 1290841 ccctcaacaa gcggtttttc atgtctctca gaaaaagaga acacaaagag tacgaatgca 1290901 agtgaaagta ggattccgac aacttgtttt ttgtaatcag tctgtgctgc cacgttgttc 1290961 tctccttcac cttttacctt ctatttaatc atagaaccaa attattttac ataatgggaa 1291021 agtcattttt ggagttagtg catttggttg aaaacagaga cgttttttga gcggagcggt 1291081 gcaattgaat ccatattgga tttgcgtgct tatgcctaag gtcacgttgt gagccaaaac 1291141 agcagtgcag aatagaaaaa aattgaaaga ttatggtaag atgaacgaaa ttcgaggggg 1291201 aatatatgat gcctgcatcg aacatcgtga tcgcctgcct gctgttatca atttaattat 1291261 ttgtggtagt ccctctcttt ttcgaaagcg ggaggtgaag tggaacatta attgctgaat 1291321 tctttcaagg ggagtgaccg tacatgaatg tgttaaaccg ccggcaagcc ttgcagcgag 1291381 cgctgctcaa tgggaaaaac aaacaggatg cgtatcatcc gtttccatgg tatgaatcga 1291441 tgagaaagga tgcgcctgtt tcctttgatg aagaaaacca agtgtggagc gtttttcttt 1291501 atgatgatgt caaaaaagtt gttggggata aagagttgtt ttccagttgc atgccgcagc 1291561 agacaagctc tattggaaat tccatcatta acatggaccc gccgaagcat acaaaaatcc 1291621 gttcagtcgt gaacaaagcc tttactccgc gcgtgatgaa gcaatgggaa ccgagaattc 1291681 aagaaatcac agatgaactg attcaaaaat ttcaggggcg cagtgagttt gaccttgttc 1291741 acgatttttc atacccgctt ccggttattg tgatatctga gctgctggga gtgccttcag 1291801 cgcatatgga acagtttaaa gcatggtctg atcttctggt cagtacaccg aaggataaaa 1291861 gtgaagaagc tgaaaaagcc tttttggaag aacgagataa gtgtgaggaa gaactggccg 1291921 cgttttttgc cggcatcata gaagaaaagc gaaacaaacc ggaacaggat attatttcta 1291981 ttttagtgga agcggaagaa acaggcgaga agctgtccgg tgaagagctg attccgtttt 1292041 gcacgctgct gctggtggcc ggaaatgaaa ccactacaaa cctgatttca aatgcgatgt 1292101 acagcatatt agaaacgcca ggcgtttacg aggaactgcg cagccatcct gaactgatgc 1292161 ctcaggcagt ggaggaagcc ttgcgtttca gagcgccggc cccggttttg aggcgcattg 1292221 ccaagcggga tacggagatc ggggggcacc tgattaaaga aggtgatatg gttttggcgt 1292281 ttgtggcatc ggcaaatcgt gatgaagcaa agtttgacag accgcacatg tttgatatcc 1292341 gccgccatcc caatccgcat attgcgtttg gccacggcat ccatttttgc cttggggccc 1292401 cgcttgcccg tcttgaagca aatatcgcgt taacgtcttt gatttctgct tttcctcata 1292461 tggagtgcgt cagtatcact ccgattgaaa acagtgtgat atacggatta aagagcttcc 1292521 gtgtgaaaat gtaatagata aggagactgg agattcatga aaaagtacca tatttcgatg 1292581 atcaatatcc cggcgtacgg acatgtcaat cctacgcttg ctttagtaga gaagctttgt 1292641 gagaaagggc accgtgtcac gtacgcgacg actgaggagt ttgcgcccgc tgttcagcaa 1292701 gccggtggag aagcattgat ctatcataca tccttgaata ttgatcctaa gcaaatcagg 1292761 gagatgatgg aaaagaatga cgcgcccctc agccttttga aagaatcact cagcattctg 1292821 ccgcagcttg aggagttata taaggatgat cagcctgatc tgatcatcta tgactttgtt 1292881 gcgctggctg gtaaattgtt tgctgaaaag cttaatgttc cggtcattaa gctctgttcg 1292941 tcatatgccc aaaatgaatc ctttcagtta ggaaatgaag acatgctgaa aaaaataaga 1293001 gaagcagagg ctgaatttaa agcctacttg gagcaagaga agttgccggc tgtttcattt 1293061 gaacagttag ctgtgccgga agcattaaat attgtcttta tgccgaagtc ttttcagatt 1293121 cagcatgaga cgttcgatga ccgtttctgt tttgtcggcc cctctctcgg agaacggaag 1293181 gaaaaagaaa gcctgttgat tgacaaggat gatcgcccgc ttatgctgat ttctttgggt 1293241 acggcgttta acgcatggcc ggaattttac aagatgtgca tcaaggcatt tcgggattct 1293301 tcatggcaag tgatcatgtc ggttgggaaa acgattgatc cagaaagctt ggaggatatt 1293361 cctgctaact ttaccattcg ccaaagtgtg ccgcagcttg aggtgttaga gaaagctgat 1293421 ttgttcatct ctcatggcgg gatgaacagt acgatggaag cgatgaacgc aggtgtgccg 1293481 cttgtcgtca ttccgcaaat gtatgagcag gagctcactg caaatcgggt tgatgaatta 1293541 ggccttggcg tttatttgcc gaaagaggaa gtgactgttt ccagcctgca ggaagcggtt 1293601 caggctgtat ccagtgatca agagctgctc agccgcgtca agaatatgca aaaggatgta 1293661 aaagaagctg gcggagcgga gcgtgcggca gctgagattg aagcgtttat gaaaaaatcc 1293721 gctgtcccgc agtaaaaaca taaaaaccga aatcaatttg atttcggttt tctgtttaaa 1293781 tatttttttt catcccgcat ctccggcatt ctctaagaaa ttttccgcct tttacagagc 1293841 ttttgaacag tgtgtaatca cagttgtcgc agcgcccgct gcgggcatcc ggatattcat 1293901 tgaattcgta aacaatcgat gtatcgtagc cttttgtttc atattcttct tttttggttt 1293961 ccatgtcgat cctccgttac aagacgtgtc tgctgtttat cttacagcaa gcttccggcg 1294021 tattcaatgg attttaggag gttgggttta tcttgatttc tcccttggtt tgcgccaaaa 1294081 tagctttatt aagcttatat acataaaaag cctatgcaaa gaggagagga aacgggtatg 1294141 ggaaaagggt tacttggaaa acgcgtggca atcggtggct cacgaaaaac ggaagaaatt 1294201 agtacaatca ttgaaaaaca gggcggaata cctgtcatcc ggcctctcca aggtacagtt 1294261 tacttagcag agaagcaggt ggagccggat ttgcggacgt ttgcggaaga aaaagctgac 1294321 tgggtcattt tcacgacagg catcgggttg gagactcttg tcgatatggc agagaaaatt 1294381 ggactgaaag atgagtttct gcaggccatt cgccaagcga aagcggcatg ccggggatac 1294441 aaaacgctgt ctgcgctgaa aaagcttgga atcacaccgg aagcttcgga tgaagacggg 1294501 acaacaagag gcttaatccg ttccttggag cctcacgact tttcaggaaa aacagtcatg 1294561 gtgcagcttc atggcgaaaa agcgccggct ctcatggcat ttcttgaaga aaaaggcgcg 1294621 tctgtcctgc cgattctgcc ttatcagcac atcccgccgg aggaggaaac ggtggagcgg 1294681 ttatgccgag agctgatgaa cgatgaggtc gatgccgttt gttttacaac ggccattcag 1294741 gttcgttccc tgtttgattt tgccaagggg cgaggttata tcaatgaagt gaagaaggta 1294801 ttcgaagaac gcgccatcgc agctgctgtc ggaaaagtga ctgctgaagc actgcgggaa 1294861 gagggcatta cgagactgct tgcgccagag attgagcgga tgggtgcgat gattgttgag 1294921 ctggccaagt attatgaaga aaaggaataa caagtacaaa aagccgcttt tccctcggaa 1294981 agcggctttt gtctgtcatt cattttgctt cagctgctga tgaacggtga ataatgatgg 1295041 gtatgtcagc acgcttaaga ttacacaagt cagcgcggct gaggccatcg ttgtaaacac 1295101 gattaagagt tgaaagcgta ctgcctgaat cgggtccgcg ccggctagaa tctggccagt 1295161 catcatgccg ggaagctgga caagacccag tgttttctgg ctttcgagcg tcgggatcat 1295221 actcattttc atcgctgagg taagaatgcg ctgtatggat tgcttcggtg tgccgccaag 1295281 tgacaatatt aattgaattt cttctttgcg aacgccgact tctgagttaa gccggtttag 1295341 aaacaaactt gagagcacca tcgaatttcc gatgaccatc ccgctgatcg gaatgacata 1295401 tcgtgccgta agcggaatga tatgaagaga cagcagaatt ccctgcgtca caatttctac 1295461 gattgctaac gcggcaaaca ccctccaaaa cgaaccgata gtatttttct ttcgcttgat 1295521 gacattttgc gccgccaccg cgagcattaa cagcaccatc agcaggataa aaacagggtg 1295581 gtctccgcga aaaatcagcg acaaaacata accgatgata agcagctgca ccgcggcccg 1295641 gatggtggcg atgatcatgt ctttttctac accggcttta aaggattttg ataaaaacaa 1295701 ggcgatcaaa acaaagatca tcgttaaaga gagagaaagg taatccatta ccgagtgcct 1295761 cccttcaaaa attctttcgc tgcttcatgc tgcggagcgg agaaaaatgt gtcggtttca 1295821 gcgatttcaa gcagccggcc atctgccata aaccaaatgg tatcggctat tcgttttgcc 1295881 tgctccatat tatgagtgac ccacatgact gtccattttt tctcttgatg ctgacgtttg 1295941 atcagttctt caatctcaag agcagagacc gggtccaagg ccgatgtgat ttcgtccaac 1296001 aatagaatgg aggaaggatt tgagagcgtt ctggccagtg acagtctttg ccgctgcccg 1296061 cccgataagt ctctggcgct tctgtctaac aactctggcg gcagccctgc aagcgaagcc 1296121 agcttttcag gagagtacag ctgggattga tgcagccttt gtacaagact taaattgtca 1296181 cgcactgtcc cgtcgagcac gggagccgat tgaaacgcga gggctgccgt tcgcctcagc 1296241 tcattgacat tccattctct gacttccttt ccgtatatgt tgacttcgcc gctgtcaggc 1296301 gttctcatta aattacacat agaaaggagg gtgcttttgc ctgagccgga agggcctaaa 1296361 acggctacga ttgcaccctg ttgaatgtct ccggtgacat cctgcagcac atcataggtt 1296421 tgtccatctt gtttatagct ttttctgact gatctgaagg agatggctgg tatgttttgt 1296481 gtttgatcgt ttgcttccat tacaataatc acctttcaat ataagtaggc tgacattata 1296541 tttaactata acgtgaaaca gattcctttt ggtagcacaa ataaaggaga acaggctttc 1296601 acccattctc ctgcagatgc tacgcagtca gatttgactg tgctttcttt ttcggttttc 1296661 tcggctgtga agcgaaggta tgtaacatca tccccgctat tataatgaac aaaccggcaa 1296721 atgataatag agatgggaaa acgcctgaca gcagaacaat ttcaccaagc agcgcgaaaa 1296781 tcacttcacc ggattgagtg gcttcaacag ctgcgagttt ttgcggattg tctcttacca 1296841 tatcagtggc ccagaaaaat aaaaccgtcg caatgatgcc tgagctgacg gcaacgataa 1296901 aggattgaac ggtttgactt gctgttggaa ggccatctga ccaccagccg taagctgcta 1296961 atataagcca gaatggaagg cttgccaatg tcattccaag cacgcgctga aatgtatcaa 1297021 gccggcctcc gtattcttcg agcattcttc ggtttcctaa cggataggca aaagccgcaa 1297081 tgacaaccgg cagcacactg aaaagcagca tcctcccaga aagcgattct gcatgctgaa 1297141 gctgaatcag agccgctcca atcaggatga tcacagaagt gccaagtgaa accaggggaa 1297201 tcttttggcg aatgagctgc ggaccgcccg gcatatcttg tttgacataa aacaaaggag 1297261 ataagagcac cccggctaca attgtaattt gccaggttcc agctatgagc caccccggac 1297321 cgtatgcagc cgcaaatgta atcggtgcgt aaaaaagcac gaaaccgacg aagctccatt 1297381 tgatccaata aaacggcttt ttcctcattt ctagtaagag aggcgtgaat gtccctctca 1297441 tgatgacaat caaacataaa aatggcacca taaaaataaa gcgcagcgaa gagctccaaa 1297501 gccagctgcc tcctgataac tccatcgctc tgtttaatat aaaggtaacg gcgaaaaaga 1297561 gtgaagccaa tattccgata acgatagctt tcatgatatc cctcattctg gcattatttt 1297621 tttatactat actattcggt atcatgcaga tcaatggaat catgagaaaa acatcatgtt 1297681 tggcgaaccg ctatatgtgg aagacaaaaa agggaggtga aattgatgga aagagagaca 1297741 cagacatact tctttccgga tgacggcagg attccgaatc accctgattt tccgctcgtg 1297801 gtgtatcaaa acgcgcttaa ggacaccgga ctggcagagc ggatcgtcac ccggcatggc 1297861 tggtcaaaca gctggtcagg gagtgttttt ccataccatc attatcacag caatacgcat 1297921 gaagtcctga ttgcccttag gagagaggct gtgattcagt ttgggggaga aaaaggggct 1297981 gccatccctt tcaaatcagg cgacgcagtc gtgattccag ccggagtcgg acataaaaag 1298041 ctcagctcaa gccccgattt tactgtcctt ggcgcctatc ccggtggcgt tcagtacgat 1298101 atgaagacgg ggaagccgaa tgagcgggag gaagcggtca aacagattaa gcaggcggcg 1298161 ttgccggcga atgatccgat cacaggaaaa agagagcctc tattggaaat atgggtaaag 1298221 tgaaggggag aaattgctgg attgtcaata actagtgccg cagaaacgat atgacatgag 1298281 ctccatataa attaatttca taatcgaagc aattcacgtt caaattttgt tcaaaaagtg 1298341 ttatcatata gaaggtaatc gaattggagt tttttgtgtt tgctattttc agagagagta 1298401 aaggattttg acttattcaa ttgtttattt ttagataaaa ataatactga atatggcaag 1298461 atgaaaaact gggtagtaaa catttatttt tgtaaatgat tgtgcatgaa ttcacaatcc 1298521 ttattcttat gccttaaaag cgtgagacag ggagaggcac taccctttcc aaaaaaatca 1298581 gcaaactgct tatagtaaag gagaattgga tatgccagaa acaatcgatc aaacaaatgc 1298641 gtctgtcagc caaagccagc aagatcttat tgatcagcta ttaaagccag aagttcaaga 1298701 atcattgact gttttagttg accagcttcc gaagctgact gagttagtga atattttaac 1298761 gaagtcttat gatttcgctc agtctgtagc gactgacgaa gtgttaaaga gcgacacagt 1298821 cggtgcgatc actgaaattc tcgagcctgt aaaagaaaca gcgaaagaag tagctgcgac 1298881 tgcgatcgaa gcaaaagacc gcgcggaagc aagcaacgaa acaattggac ttttcggcct 1298941 tcttcgcatg ctgaaagatc ctcaagctca aaagctgttc cgttttgcta acagctacct 1299001 tgaagtcatg aacgaacgcg aaaaccaaaa ataatctcag attcaaattg atataaagga 1299061 cggaggatat acgatgtcaa aacatattgt cattctaggc gctggttatg gcggagttct 1299121 ttctgctcta acagttcgca aacattacac aaaagaacaa gcacgcgtga cagtggtaaa 1299181 caaataccca actcaccaaa tcattacgga attacaccgc cttgctgcag gcaacgtgtc 1299241 tgaaaaagcg gttgcaatgc cattagaaaa acttttcaaa ggcaaagaca ttgatcttaa 1299301 aattgcggaa gtaagctctt tctctgttga taaaaaagaa gttgcgcttg ctgacggttc 1299361 tacattaact tacgatgcgc ttgttgtagg tcttggttct gtaacggctt acttcggcat 1299421 cccaggtctt gaagaaaaca gcatggtatt gaaatctgct gccgatgcga acaaagtctt 1299481 ccaacatgtt gaagatcgtg tgcgcgagta ctctaaaacg aaaaacgaag cagatgcaac 1299541 aatccttatc ggcggaggcg gcttaacagg tgttgagctt gttggtgagc ttgctgacat 1299601 catgccgaac cttgcgaaaa aatacggcgt agaccataaa gaaatcaaat tgaaacttgt 1299661 tgaagcaggt ccgaagatcc ttcctgttct tccggatgat cttatcgagc gtgcgactgc 1299721 aagccttgaa aaacgcggcg ttgagttctt aacaggtctt cctgttacaa atgtagaagg 1299781 aaacgtaatc gatctgaaag acggatctaa agttgttgcc aacacatttg tttggactgg 1299841 cggcgtacaa ggtaacccat tagtcggtga atcaggccta gaagtgaacc gcggacgcgc 1299901 gactgtaaat gacttcctgc aatctacatc tcatgaagat gtattcgttg ctggagacag 1299961 cgcagtttac ttcggtccag acggccgtcc atacccgcca actgcacaaa tcgcatggca 1300021 aatgggtgag ctgatcggtt acaacctatt cgcttaccta gaaggcaaaa cgcttgaaac 1300081 attcaagcca gtaaactctg gtacacttgc aagccttgga cgcaaagacg cggttgccat 1300141 cattggtgct aattctacac cgcttaaagg tcttcctgct tccttgatga aagaagcaag 1300201 taatgtacga tatttgacac atattaaagg acttttcagc ctggcttact aatcctttta 1300261 atgaatctgg cattgccaaa agcattcctt tccgagtgct ttctggcaat gtcttttttt 1300321 atgtttatga cagcgttaac atttcatttt caaaaaagag attgatccca aaggaatata 1300381 aaggtaaaat aaaaacaaat caaaatgtta acgttaacat tttgaaatag aatgaaagac 1300441 ggtgaggaca tggaaccctt catgggcaaa aactttttat tgaaaaatga aaccgctgtc 1300501 agcctctatc acaattatgc gaaagacatg ccaattattg attaccactg ccacttaagt 1300561 ccgaaagaaa tctatgaaaa taagacattt caaaacatca cggaagcctg gctgtatggt 1300621 gaccattata aatggcgcat catgagagcc aatggaattg aggagacata cattaccgga 1300681 gatgcgcctg atgaggagaa atttatggct tgggcgaaaa ccgtgccgat ggcgattggc 1300741 aacccgctct acaactggac tcacttagaa ttgcagcgtt tttttggcat ttacgagatt 1300801 ttaaacgaga agtccgggtc ggctatatgg aaacagacaa ataaactgct caaaggggaa 1300861 ggcttcgggg caagggattt aatcgtgaaa tcaaatgtaa aggtcgtgtg caccacagat 1300921 gaccctgttg attctcttga ataccattta ttgttaaaag aagacaaaga ctttcctgtc 1300981 agtgtgctgc ctggatttcg gccggataaa ggacttgaga tcaatcgtga aggctttcct 1301041 gagtgggtgc aggcgcttga agatgccgct gccatatcga ttacaaccta tgatgagttt 1301101 ttaaaggcgt tggaaaaacg agtgcgattc ttccactcag ccggcggcag agtttctgat 1301161 cacgcgatag atacaatggt atttgccgaa acaacaaaag aagaagctgg acggattttt 1301221 tctgacagat tacaaggaac agaggtttct tgtgaagatg agaagaaatt taagacatat 1301281 acgcttcagt ttctttgcgg tttgtatgcg gagctcgatt gggcgatgca gtttcatatc 1301341 aacgctttaa gaaacacgaa tacaaaaatg atgaaaaggc tcggacctga tacagggtat 1301401 gattcaatga acgatgaaga aattgctaag cctttataca agctgctgaa ctcagttgag 1301461 atgaagaacc agctgccgaa aacgatttta tattcactga atccaaatga taactatgtc 1301521 atcgccagca tgatcaacag ttttcaggac ggtattaccc cgggaaaaat acaattcggc 1301581 acagcctggt ggtttaacga tactaaagac ggaatgctcg accaaatgaa agcgttatca 1301641 aatgttggcc ttttcagccg ttttatcggc atgctcaccg attccagaag ctttctttcg 1301701 tatacgcgcc acgaatattt caggcggatc gtctgcaatt tgattggaga atgggtggaa 1301761 aacggcgaag tgccgcgcga tatggagctt ctgggaagca tcgttcaggg gatttgctat 1301821 gacaatgcga aacactactt tcaatttcaa gaagagaaag caaacgtgta acaaagtgtc 1301881 cgctcagtat cgctgagcgg atcactatcc gaaaattctt aagacacaga ggtggaacat 1301941 gcgaactgaa ctggcaaata aggttgtgtc ggtcgaaacg gaaaaaaggc tttcattgaa 1302001 agagaaaatg tcctatggct ttggtgattt tggcaacggt tttatgtttg atctcggcca 1302061 gatttattta ttgaagtatt tcactgatgt agcgggaatc cccgctgcga tggccggcgg 1302121 cattttttta gtcagtaagc tgtttgcagc gataacagat ccaattgtcg gctcatcaat 1302181 cgattatcgc aaaaacatcg gcaaacgggg gaaattcagg ccttatctat taatcggcag 1302241 catcgtgctt gcggtgctta ctgttcttat ttttctgtct cccaatgtat caacgaccgg 1302301 aaaactgata tatgcatatg catcctatat gatttggggc atcggctatt cgtttgtgaa 1302361 tattccgtac ggctcattag gggcagcgat gactcaaaat tctgaggacc ggacctccat 1302421 ttcgacgttc cgccaaatcg gatcacttgg cgccttgttt atcacaagtg tggccgtgat 1302481 gccgctgctc gtcaagtttg ataatccgaa ggtcggctac ccggtggtca tgggcttgtt 1302541 cgccgcgctc ggtgtgtttt ggttttatat ttgctaccgc aactgcaaag agcgcattat 1302601 catatcggaa gcacccaaag aaaaattaac actctcatct gtcgtcaaaa catttattac 1302661 aaataaaccg ctgttaaccc ttgtcctgat gacgattttt tcaatttccg catacaacat 1302721 taaatccgcc atgctcgtct atttcgcaca atataacttg ggcaatgttg aattaatggc 1302781 ttatatgaac ttcatcatta ttggttcttc ctttttgggc gtcgtattcc ttccaaagct 1302841 cgtcaagatg tttggaaaga aacgaacggc aatgatcggc tttggcatca gtgtggccgc 1302901 ggatctgatc aactttatgc ttccatctaa cgtttatgtg tttacaattc tcgccagtat 1302961 cgcctttatc ggaatcagta tcccaaatgg catcacgtgg gctcttgtct ccgatattat 1303021 cgactatggc gaatggaaat ccggtgaacg gaaggaagca acgacatatt cacttttcaa 1303081 tttctcaaga aagcttgctc aatctttgtc tggctttctc tcggggatcg gtttggggat 1303141 tatcggctat gtgccgaatg cagtccagac agcacaggcg ctgattggca tcaaagcgct 1303201 gcttcttctg tatccggcca ttgctttggc attagcgatg ttcattatcg gctttcttta 1303261 taaactcaca gaccagcagc atgctcagat cgttcaggat cttcatcaaa agagctgaca 1303321 atataatata aagaatattt aaaataattt gtaaataaaa tgtgtttgta ggggtttcgc 1303381 ttggagagtg cccaaaaaac tgaaaaggaa ggaggcactt gcttgaaaac gataacaatt 1303441 gcagctgaag aagcaaagga actcgtttgg caaaagctgg acggtgccgg tttgaatgaa 1303501 cgagatgctg aaaaagtggc agatgttctc gtgcacgctg atttgcgcaa tgtacattcg 1303561 catggcgtgc tgcacacaga acactatgtg aacaggcttt tagcgggagg gatcaatcct 1303621 ggggcacagc ctgtttttaa agagacgggg cctgtgaccg gggtgcttga cggagacgat 1303681 ggtttcggtc atgtgaattg cgacatggcg atggaccatg caattgacat ggcgaagaaa 1303741 aaaggagtcg gcatggtcac ggccgtaaac agcagccatt gcggagcgct aagctatttt 1303801 gtgcaaaaag cggctgacga aaagctgatc ggaatggcaa tgacgcatac agacagtatc 1303861 gttgtcccat ttggggggag gactcctatt ttagggacaa atccgattgc ttacggagtt 1303921 ccggctaagc ataaaaaacc gtttatccta gatatggcga catccaaagt ggcttttggg 1303981 aagattctgc aggcccgtga agagggcaaa gaaattcctg aaggatgggg agtcgatgaa 1304041 aacggagaag cagtaactga tcctgacaag gtcgtctcac tttcaacatt cgggggcccg 1304101 aaaggctatg gactatcgat tgtagtggat gtgttttccg gattgctggc gggcgcggct 1304161 tttggccctc atattgccaa aatgtacaac ggccttgatc aaaaaagaaa gctggggcat 1304221 tacgtttgcg cgatcaatcc atcctttttt actgactggg atacgttttt agagcagatg 1304281 gatgccatga ttgatgaact gcagcaatca ccgccggctg ttggattcga aagagtgtat 1304341 gtgcccggcg agatcgagca gctgcatgaa gaaagaaata agaaaaacgg aatttctatc 1304401 gcccggagcg tgtatgaatt cttaaaaagc aggtgagtaa aatgaaagcg gttcaagtgc 1304461 gaaaagcgta tgatctggtg acagcggagg tgaagaagcc agttctttca aaggatgatg 1304521 aagtgctcgt gaaagtcaag cgagtcggca tttgcggttc agacatgcac atttatcatg 1304581 gaacgaatcc gctcgctacc ctcccgagag tcatcggaca cgaggtaacg ggacaagtgg 1304641 aggcagttgg tgcgaatgta cagagcctaa aacccggtga tcatgtggtg attgagccga 1304701 tttcttattg cggatcgtgc tatgcctgcc gcaaagggcg gccgaatgtt tgcgccaagc 1304761 tttctgtatt tggcgtacat gaggacggag gcatgcggga atatattgtg cttccggaaa 1304821 gacagcttca cgcggtctca aaggacttgc cttgggagga agcagtcatg gccgagcctt 1304881 atacgatagg cgcccaggca gtgtggagag gccaggtgga aaaaggtgat accgtcctga 1304941 tccagggagc ggggcccatc gggatctgtg tgttaaaaat ggcaaaactg gcgggcgctg 1305001 ctgtcatgat gactgacttg aacaacgagc ggctggcatt tgcgaaagaa aacggcgccg 1305061 atgctgttgt aaatgtccaa gcagaacatg ttgccgagcg ggtccttgaa tggactggga 1305121 atgaaggagc aaacgtggtc attgatgctg tttgcctgcc ggagactttt gcactttcaa 1305181 ttgaggctgt gtcaccggcg ggacatgtgg ttgtgcttgg atttgatgaa agagcggctc 1305241 agatttctca gctgccaatt acaaaaaaag aagtcacgat aaccggatcc cgattgcaga 1305301 ccaatcagtt tccaaaagtg gtagagcttt tgaatggagg ccggttaatg cataacgggc 1305361 tggtgaccca tacattttca gttgatgacg ttcatcatgc atttcagttt attaaggagc 1305421 atccagatca ggtgcggaaa gccgtcatca cgtttgatta aatgactgaa tccggaggtg 1305481 cgagcatgaa tatgacattc cgatggtatg gacgaggcaa cgatacagtc acacttgaat 1305541 acgtgaagca aattcccggt gtcaaaggca tcgtttgggc tctccatcaa aagcccgtcg 1305601 gcgacgtgtg ggaaaaagaa gaaatcagag ccgaaactga atatattcaa tcctatggtt 1305661 ttcatgctga agttgtagaa agcgtgaatg ttcacgaagc gattaaactt gggaacgaag 1305721 aacgcggccg gtatattgaa aactacaagc aaacgatccg caaccttgcc ggatttggcg 1305781 tgaaagtgat ctgctataat tttatgccgg tttttgattg gacacgcacg gacatgttcc 1305841 ggccgctaga agatggatcg accgctctgt tttttgaaaa ggccaaggtg gaaagccttg 1305901 atcctcaaga gctgattcgg acggtggagg aagcatccga catgacactg ccggggtggg 1305961 agcccgaaaa attggctcgg atcaaagagc tttttgctgc ctacagaacg gtcgatgaag 1306021 aaaagctatg ggacaattta tcattctttt tgcaggaaat tcttcctgtt gctgaggcct 1306081 atggtgttca aatggccatt catccggatg acccgccgtg gccgattttc ggactgccgc 1306141 gcattatcac aggagaggca agctataaga aactgcgggc gatatcagat tcaccgtcta 1306201 attgtatcac cctttgtaca ggttcaatgg gagccaatcc cgctaacgac atggtggaga 1306261 tcgctaaaac gtatgccggc atcgctccat tttcacatat tcgcaatgtg aaaatttatg 1306321 agaatggcga ttttattgaa acatctcatt taacaaagga tggttcgatc aacattcaag 1306381 gcgtgatgga agaactgcat aagcaggatt acgaaggata tgtcagaccg gatcatgggc 1306441 gccatctttg gggcgagcaa tgccgcccgg gatatggctt atacgatcgg gcacttggca 1306501 tcatgtattt gaacgggctg tgggacgctt atgaagcaat ggcaaaaaaa gaggtgggca 1306561 tatgatcccg ctgcatgaga acctggctgg taaaacggct gtcatcactg gcggcagcgg 1306621 cgtgctttgc tctgcgatgg cccgggagct agcccgtcat ggcatgaagg tggcgatttt 1306681 gaatcggacg gctgaaaaag gccaagcggt cgtgaaggag ataacggcgg ctggcggcac 1306741 agcgtgcgct gttgctgcgg atgtgctgga caggatgtca ctggagcggg caaaggaaga 1306801 catccttggc caatttggcg ctgttgatct gttaattaac ggggctggcg gcaatcatcc 1306861 tgacgcgata accgatgtgg agacatatga agaagcggga gaaggccaat ccttttttga 1306921 tatggatgag aggggctttc taactgtatt ctccaccaac ttcaccggtg cgtttctggc 1306981 ctcgcaagtg tttggtaaag aactgctgaa ggcggattca cccgcgatca tcaacctttc 1307041 ttccatgagt gcttattcac ctatgacgaa ggttccggca tacagtgctg cgaaagcatc 1307101 catcaataat tttacgatgt ggatggctgt tcattttgcc gaaaccgggc tgcgggtcaa 1307161 tgcgattgcc ccaggcttct ttctgacaaa acaaaatcat gatctgctga tcaaccaaga 1307221 cggaacgttc accagccgat ctcacaaaat tattgcggga acaccgatga agcgcttcgg 1307281 aaaaccggag gatttgctcg gtacgctcct ttggctggcg gatgaatcct attccggttt 1307341 tgtcactggg atcaccgttc ctgtcgatgg aggatttatg gcttattcag gtgtgtaacg 1307401 aaagcggtgc aacagaaact gaaccaacat aggggtgagg ttgagatgtt ttcaaaagat 1307461 aagcttcccg ttatcctttt tttgttcctg gcaggggtga ttaattacct ggatcgctcg 1307521 gcgctttcca ttgcagctcc ttttattcag gatgatctca cattgtctgc cacacaaatg 1307581 ggcttgattt tcagcagttt ttcgataggt tatgccattt ttaattttct tgggggcgtg 1307641 gcatccgacc gctatggggc aaagctgacc ttgtttgtcg cgatggttgt ttggtcgctg 1307701 tttagcggag cagtcgccct cgcttttggc tttgtcagcc tgctgattat acgcattctc 1307761 ttcggaatgg gagaaggccc gctttcggcg accatcaaca agatggtgaa caactggttc 1307821 ccgccgaccc agcgggcgtc cgttatcggt gtaaccaaca gcggcacgcc cctcggggga 1307881 gccatttccg gcccgatagt cggcatgatc gcagtggcgt tcagctggaa ggtatccttc 1307941 gttctcatta tgattattgg attgatatgg gcagtgctct ggttcaagtt tgtcaaagaa 1308001 aagccgcaag agacgatcaa ggaagcaccg gcaataaaag cagaaacgtc tcccggagaa 1308061 aaaattccgc tcacctttta cctgaagcaa aaaacagtcc tgttcacggc gttcgctttt 1308121 ttcgcttaca actacatcct cttcttcttt ttgacatggt ttccgagcta tcttgtcgac 1308181 gagcggggat taagtgttga atcgatgagt gtcatcacgg tcataccgtg gattttagga 1308241 tttatcgggc tggctgcggg gggatttgtt tctgactatg tgtacaaaaa aacggcccga 1308301 aaaggtgtgc tgttctcgcg caaggttgtg cttgtcacgt gtttgttttc atcagctgtc 1308361 ctgattggtt ttgccgggct tgtggcaacg actgcggggg ctgtcactct tgtcgctctg 1308421 tcagtgttct ttctttattt gaccggtgct atctattggg ctgtcattca agatgtggtt 1308481 gatcaaaaca atgtcggttc tgttggcggc ttcatgcatt tcctcgccaa cacggcagga 1308541 attatcggcc cggctttaac cggatttatt gttgaccaaa caggcacgtt ttctggagca 1308601 tttttgcttg ccggtgggct ggctgtcttc gcttcacttg ctgtgattcg ttttgtccgt 1308661 ccaatcattg gtaagccagc gggaacagaa gctgagaatc ctgtgtctta ttaatctgga 1308721 aatatagtgg gagaggcggt atgtttgatg atacaatata cagtaaataa tcgcagccgg 1308781 tatgataagg aagggaatta gatggtaacc ataaaagata tcgcaaaact cgcaaacgta 1308841 tcccacacta ctgtttccag agcactcaac aacagccctt acatcaaaga acatacgaag 1308901 aaaaaaatat tagagctagc agagcagctc aactatacac caaatgtaaa tgcgaaaagt 1308961 ctggcgatgc aaaagtcgca tacgatcggg ctattcttta caagcattac aaacggaacc 1309021 tcacacagct tctttgcaga cactatcaaa ggcgtcaatc aagccataag tgaggattac 1309081 aatctgtatg tgcgcggcat tgatgatctg aaaaactatg actccgttac accgatgaga 1309141 tatgacggca tcattttaat gagccaaagt gacattgata attcttttat ttaccatatt 1309201 cgcgaaaaaa acattccgct tgtcgtgctg aatcgtgata ttgatgatcg taccatcacg 1309261 aatattttgt ccaatgacaa ggaaggctct caagaagctg tagaatactt cattcagtcc 1309321 ggacatcaag acatcgccat catcgagggg atcgaaggct ttaaatcctc ccagcagcga 1309381 aaggaagggt acttatccgc actgattcaa catcatattc cgatcaagca tgaatacagt 1309441 gtcaaaggac agtacgatat ggaaagcggc tttcaagcga tggagcggct gctggcactg 1309501 ccgaatcctc caaccgctgt tttttgttcg aatgatgaca tggcaatcgg agcgatgaat 1309561 gcgatattcg caaagggcct gcgcgttcct gatgatattt cggtgatcgg gtttgatgat 1309621 attgggtttt cacagtacat cacgccaagg ctttcaacag taaagcgccc agtggagaaa 1309681 ataagcgtgc tcggtgcgca aaaactcttg tcgctgatca gcgagcccga aacaaaagca 1309741 gaaaaaatct tggaaaacac agaatttatg gtgcgtgatt cagtcagacg attgacgacg 1309801 tgatgtcccg tttttcagcg ggcattcttt atacagaaaa atgttaacgt gtgcataaag 1309861 tgagagggag gcaataaggg tgcagaagct gaataaaaat gtgtacgatc actatactca 1309921 gtatccagaa aaaattctcc aattcggaga aggaaacttt cttcggggat ttatcgattg 1309981 gcagattgat caattgaatc aacacactga ttttaatggg agcgtggcag ttgtccagcc 1310041 aagaggctca gaaaaaatca aacgattaaa tgagcaagat ggattatata cacttttttt 1310101 acaaggaatg aaagacggag aagcggtaaa cgagcatatg attatcaact caatcagccg 1310161 gggaattgac ctgttttctg attatgaagc atacaaagaa ttggcatcaa gcgaaaggct 1310221 tcggtttatt atctccaaca ccactgaggc tgggattgta tgtgatgaaa aagatcgttt 1310281 agaggatagg ccgcaaaaaa cattccctgg gaaattaact gcatttcttt actttcgcta 1310341 tcaggctttt aaaggagatc agacaaaagg gtgtgtcctg atcccatgtg aactgatcga 1310401 gaataacggt gaaaagctga gggaaacggt tcttcattat gcacatctgt ggaagctgga 1310461 ggaaggattt acacagtgga ttcatgaggc caatacattt tgtaatagtt tagtagaccg 1310521 gattgttccg ggttttcccg tcgacagcat tgatgagatc acggcagatc ttggctatca 1310581 ggatgatttg atagttgtgg gagagcaata ttatttgtgg gttatcgagg ggcctgattg 1310641 gattggaaaa gaacttccct ttgcggctgc agggctgcat acaaagatcg tcagcgacct 1310701 caccccatac cggactaaaa aagtaagaat tttaaatggc gctcatacag caatgacgcc 1310761 agtggcttta ttatacggct tgaagactgt tagggatgca gtcgagcatc cggaagtggg 1310821 gcgatttata agagagctga ttgatgacga aattcttcct gttttaaaaa tggaaggtct 1310881 ttctcagtat gctgacgatg tgctgaaccg ttttaaaaac ccgtatatta agcattacct 1310941 ggaaagcatt gcattgaacg ccatttccaa attcaaaacg agaaacctgc cgactcttaa 1311001 ggaatatgct gaacaaaagg gacagcttcc tgaacgcttg gtgttttctt tcagcgctct 1311061 tctgtatttt tatcatgata acgagacatt gcaggatgat ccggcagttc ttcaattttt 1311121 caaagaggtt tggtgtcagg aggatggcga catgcttcgg attgcatcaa gagtgttagg 1311181 cgaacagcgg ctgtgggggg cagatctcaa tgagataccg aagctgactg atagagtcgc 1311241 tgtttacttg aatcatattc atgagctggg catgcagagg gctcttgaac aatactgcat 1311301 acaaggggga gaggtacgtt gaagtcgttt ataaagattc ataagcaaga taatgtcctt 1311361 cttgctctgc gggatattca aaagggagag aggctgcatg cttacggcgt gtcgattgaa 1311421 gtaaaggatg atataaaaag aggccataag attgcattgc agtctatcaa agaaaacgac 1311481 agcatcgtca agtacgggtt tccaatcggt catgcatcac aagatatctc gatcggagag 1311541 catattcatg tccataatac gaaaacaaac ctgtctgata tccaattata cagctataca 1311601 ccgagatttg atgaaaatcc gtattctaat gagaaccgga cgtttaaagg ttttagaaga 1311661 gaaaacggag atgcgggtgt acggaatgaa ttgtggattg tcccaactgt cggctgtgtc 1311721 aatggaatag cagaaaaaat gctgcagcgt tttgtcagag aaacagggga tatcgctcca 1311781 tttgataacg tactggtgtt aaagcatcaa tacggatgct cgcagcttgg cgacgatcat 1311841 gaaaatacga agcagatcct gctgaatgcc attcgccatc caaatgccgg cggcgtcttg 1311901 gtgttagggc ttggctgtga aaacaatgag ctggcaagaa tgaaggaagc actgcaagat 1311961 gtgaacttga agcgggtgaa gtttctggaa tcccagtcgg tgaccgacga aatggaggca 1312021 ggcgttgctt tgctgaagga aattcatgaa gcggccaaag gagataagag agaagacatt 1312081 ccgctgtctg aactgaagat cgggctgaaa tgcggaggtt cggacggttt ttccggcata 1312141 accgcaaacc cgctgcttgg acgtttttca gattatctca ttgcacaggg agggagtact 1312201 gtgctgacgg aagtaccgga aatgttcggc gcagaaacca tcctgatgca gcgggctgcc 1312261 aatgaagaag tgtttcataa gatagtcgat ttaatcaatg atttcaaaca atactttatt 1312321 aaacatgatc agccggtgta cgaaaatcct tcaccgggca acaaagcggg cggcatttct 1312381 acacttgagg ataaatcgct gggctgtacg caaaaagcgg ggatttctcc tgtcacggat 1312441 gtcttgaaat acggtgaagt actcaagaca aaagggctga ctcttttgag cgcaccgggc 1312501 aatgatttga tcgcctcctc cgcattggcg gctgccggct gccaaattgt cctctttaca 1312561 acgggaagag gcacgccgtt tggcaccttt gtcccgacgg tgaaagtagc gacaaacacc 1312621 gagctgtatg aggcgaagcc gcattggatt gattttaacg caggcctttt agcagaggat 1312681 gatgttcatg aggaatatgt gctgcgtgag tttatccact atatgattga ggtggcaagc 1312741 ggccagcttg tgaaccatga aaaaaatgat ttcaaagaac tcgccatttt taaatcgggt 1312801 gtgacgttat aataagaaaa ggctatcctt caagcggata gccttcttca ttaaatcaat 1312861 tttaaaccgc tgactaaaat aatggaagcc ataataaatt gcagtggacg cggggagaat 1312921 cgaggcgaaa gatggctccc gatcagtacg ccgggaattg aaccgaggag cagattagct 1312981 gccagcatgt aatccacgct tccgaagctt gcgttcaaaa tgcctgctgc cgtaacaaga 1313041 agaaaagcat gcgcgatatc ggttccgaca atctgtgacg ctttcatgtt aaataagtaa 1313101 atcatggcga ttgcaaataa tgagccggac ccgattgatg ttaatccgac gataaaccca 1313161 aacacaacac caataagaat tgtcagcgcc ctcttatttt caagcggcat cagctgccag 1313221 cggttggggc gaagttttct atccaaaaac aaacgaacga tgattgaaat ggcaaccagc 1313281 gttaacacat atcctagagc gtgcttaata atttcttcct gatgctggtg aaaggcgggg 1313341 aacaaatgca atatgccaat ggctagcgaa gcactcggaa tactgccgat ggctaagtat 1313401 tttaccaatt taaagttaat cgttttctgc cgccaatggg aggcaacgcc aaacagcttt 1313461 gtgatcgagt tatatacaag atccgtaccg accgcgatgg aaggattaat tccaagcaca 1313521 attaaaaggg gagttaataa ggccgctcca cccactcccg tcaatccgac taaggctccg 1313581 acaaacaaac ccatcaatat gatgcttaca ctcatgataa aggcctcctg aaaacccgac 1313641 tatttttatc agattatata tgattaggac gcgttaatca attaaatttt ttgaattttt 1313701 gcacgttagt tgcttgaaat tttggtatgc tcaatatctc tattcatttg ccctataatg 1313761 agtgtctgga cgaaatcgag aagtactaaa ggcgcaaaaa aaagatacct cttaacaggt 1313821 atcttttttc ttgtttacgc tacatgcgct gctgatagaa aggaagctca gtgtggccca 1313881 tttcccgcac atacacgaac aggttgcctt tatggtgaat ttcatgctcc attgcaagct 1313941 gaagcagcgc gcggcctgtg acttttctgc cgaaagcgga tgtcagatca atttctctgt 1314001 ccagctgctc ttcagtcagc tgttcaagga tagcgaccgt tttttctgta tatgtttttg 1314061 ccagaacatt gagatctgtt tctgtttctt cctgcttgtt ttgaaatggt gaggcattgc 1314121 cttccttaat gacatttgcg aacaagtgga aagacgtaag aatgtgtttg accagctctt 1314181 ctgctgacat tgatgtttct gccggtttgt agctgtaatg gtctttgctg attttttcgg 1314241 caagctcatt ggtcacgttt cgatgggata aaaaatggct gacaatttga ttggattggc 1314301 acattatgat ctcctccata tgtaaaaata aatggtgcaa tgaaatccta tatcaacggt 1314361 tatgaattca caagtaatat gctgtgggat gaaacaaaat gctatgtcaa tcgtatatat 1314421 aacgttcaca aaacatgaaa tggagtataa acatgactaa catacctttc atttatcagt 1314481 acgaagaaaa agagaatgaa agagctgcgg cgggctacgg cactttcggt taccttatca 1314541 cacggattga agaaacgctt tatgatcaat acggtgtatt ctatgagctc tatgccagtg 1314601 atgatccaaa tacggaatac tgggagcttc ttgtagaaga tgtccgcagc ggttcattgg 1314661 agcctgagca tgtggcatat atatttgaaa agcttgaaaa gaaaaccttt gcttacgatg 1314721 aagatgagaa agaaccggat tataccgtcc ataagtctat aagaaacagt gtatacgcgt 1314781 atcctgaaaa gggagttgct tttgccagaa ttccatattt tcaagatggg agcattatga 1314841 gttttgattg tctgtttgcg gttaacgatg aaaagatgcg tgcatttctg gagggagtca 1314901 gaccgcgtct ttgggaaaaa agcaagcgga aagtgaccgt gtttacggat ggagatggag 1314961 ggacttcaag agagcaggaa gccattgtca gagaggttca gcggagtcaa gtcatcatga 1315021 atccgctatt gaaaaaagag atatacagat caattgatca gttttttcat agtgataaat 1315081 cgttttatca aacatatgac atcccttaca agcgcggcat tctgttatat ggacctcctg 1315141 gaaacggaaa gacgacgtta gtgaagtcga tcgcaggcag tatcgatgca cctgttgctt 1315201 attggcaaat tactgaattt acgtcgagcg agacaataga agaagtcttt caggcagcga 1315261 gacgcctcgc tcctgcagtt ctggtcatcg aggatataga ttcgatgccg gaagatgtgc 1315321 ggtccttttt tctcaatacg ctggacggcg cgacatcaaa agaggggcta tttctcatcg 1315381 gtacgacaaa ctatcccgaa gagatcgatc caggtttgat gaatcgtgca ggacgatttg 1315441 accgtgccta tgaaatcggg cttccggatg aagagctgcg gctggaatat atgaaaatga 1315501 gaggctttgg catctttttg agtgaaggag aaataaaaaa cgccgcaaaa cttacagaag 1315561 gcttttcctt tgcacagctg ggagaattat atgtatcttc agcccttcaa tggcaccaag 1315621 aagggaatca ccatattgaa accatggtga aagacatgac aggagagcaa agaaaaagcc 1315681 agcggggaag ctggatggaa agaaacaaag tcggttttca ctaaaagaaa gcacgggtgt 1315741 ttgaaaaacc cgtgcttttt tgttgcggtt agccgaaatt cgacaattgc ggttattttg 1315801 cgttcttctt tttcttgtaa atatgataaa atatgacata tctcgggtaa ttcaaaaggg 1315861 gggattaatt gaggatgaag cagacgattc cgtcctctta tgtcgggctt aaaattaatg 1315921 aatggtatac tcatatccgg cagttccacg tcgctgaagc cgaacgggtc aagctcgaag 1315981 tagaaagaga aattgaggat atggaagaag accaagattt gctgctgtat tattctttaa 1316041 tggagttcag gcaccgtgtc atgctggatt acattaagcc ttttggagag gacacgtcgc 1316101 agctagagtt ttcagaattg ttagaagaca tcgaagggaa tcagtacaag ctgacagggc 1316161 ttctcgaata ttactttaat ttttttcgag gaatgtatga atttaagcag aagatgtttg 1316221 tcagtgccat gatgtattat aaacgggcag aaaagaatct tgccctcgtc tcggatgata 1316281 ttgagaaagc agagtttgct tttaaaatgg ctgagatttt ttacaattta aaacaaacct 1316341 atgtttcgat gagctacgcc gttcaggcat tagaaacata ccaaatgtat gaaacgtaca 1316401 ccgtccgcag aatccaatgt gaattcgtta ttgcaggtaa ttatgatgat atgcagtatc 1316461 cagaaagagc attgccccac ttagaactgg ctttagatct tgcaaagaaa gaaggcaatc 1316521 cccgcctgat cagttctgcc ctatataatc tcggaaactg ctatgagaaa atgggtgaac 1316581 tgcaaaaggc agccgaatac tttgggaaat ctgtttctat ttgcaagtcg gaaaagttcg 1316641 ataatcttcc gcattctatc tactctttaa cacaagttct gtataaacaa aaaaatgacg 1316701 ccgaagcgca aaaaaagtat cgtgaaggat tggaaatcgc ccgtcaatac agtgatgaat 1316761 tatttgtgga gctttttcaa tttttacatg cgttatacgg aaaaaacatt gacacagaat 1316821 cagtctcaca cacctttcaa tttcttgaag aacatatgct gtatccttat attgaagagc 1316881 tggcgcatga tgctgcccaa ttctatatag aaaacggaca gcccgaaaaa gcactttcat 1316941 tttatgagaa aatggtgcac gcacaaaaac aaatccagag aggagattgt ttatatgaaa 1317001 tctaaatgga tgtcaggttt gttgctcgtt gcggtcgggt tcagctttac tcaggtgatg 1317061 gttcatgcag gtgaaacagc aaacacagaa gggaaaacat ttcatattgc ggcacgcaat 1317121 caaacatgat gcataaaaaa agacccttag ggctttttat ttcttcagct tccattcttt 1317181 tatcgtcagc tcagaagatc cacttgccac cagcggatcc gcatggccga tttccgctgc 1317241 ctcttccagt gaatctgctt cgatgacata cgctccgcct gtggcgtcgc tgaatggccc 1317301 aaacattttt aaacgttttt ctgcctgtaa acgatccaga aattcatagt gcccagccac 1317361 atgctcctga ttaaatttct ccgttctcat tgtcagcatt aaatatgtat acatattcag 1317421 accctccgtg aacttcagtt taacacattt atccatatta cggtgataga tgatatgagc 1317481 ttttcgtcct acgaatgcca cctatttatg aaaaaagaaa aggagagatg ataggtgagc 1317541 attccagtaa agaaaaattt ggtttctgag gcgaaatacg cgttgaagtg tcctaatgca 1317601 atgtccgctg aatacattac cattcacaac acggcaaacg atgcatcagc ggccaatgaa 1317661 atcagctata tgatcgggaa cacaagctcg acaagctttc attttgcggt cgatgatcaa 1317721 gaggtgattc aaggtctgcc gcttaaccga aacgcttggc acactggtga cggcacaaac 1317781 ggtccgggaa accgcaaatc aatcggtgtt gagatttgct acagcaaatc gggaggcccg 1317841 aagtatgagg cagctgaagc cttggcgatt tcatttgttg cacagctgtt gaaggagcgc 1317901 ggctggggca tcgatcgggt gagaaagcat caggactgga gcggaaagta ttgcccgcac 1317961 cgcattttat cagaggggcg ctgggatcaa gtgaaggcgg cgattgaaaa ggaattaaac 1318021 gggggcgtat cagcgaaaaa agctgcagtc tcttcttcgg cgtctgaata tcatgtaaaa 1318081 aaaggtgaca cactgtcagg gattgccgca tcacacgggg ccagtgtgaa aacgctgcaa 1318141 agcataaatc atatcactga cccgaaccac atcaaaatcg gacaggtgat caaactgcct 1318201 cagacggcat ctgcttctaa aagccatgcc gcatcctcat atccgctccc atccggcgtg 1318261 atcaaagtga caagcccgct gacgcaaggg acaaaagtaa agcaggtgca gactgcttta 1318321 gccgctcttt atttttatcc tgataaagga gcgaaaaatc acggcgttga cggcgtttat 1318381 ggcccgaaaa cagctaatgc agtgaaacgt tttcagtctg tcagcggttt aacggctgat 1318441 gggatttacg gtccgaaaac gaaagcgaag atggaggaaa agctgtaaat gaaaagacgg 1318501 aagctgtgaa gcttccgtct tttcgcctta catacaaact gcggcaagca ccttttgaat 1318561 atcataaatg ctttcatctt ttttaaactg ctttgagaca gcgggaagtt ccgcgccgga 1318621 gatccaaatt ttcagctctg aatcaaggtc aaagcggccg gcagtttcca cgctgaatct 1318681 ggaaatgctt ttgtacggaa tcgattgaaa ttccgttttc ttgcctgtaa ttccctgttt 1318741 atctacaagg ataagccgct tgtcagtaaa gacaatcaaa tcgcgaacca gcttaaacgc 1318801 ggcttcaacc ttctcaccct caagtaaaat atgggcaagc tcttcttgca cagctgccgt 1318861 tgacagtgtt gatgcattgc cgagtaatcc atcaataaac cccatcatat acctcctctg 1318921 cgtattctat caaatcatac tataaaaaag gttttcattc atagatgagt agagtaaact 1318981 ggtgctgact ggtaaagggg ggcgttcaag atggaagata tgtatgacag ctttgcggcc 1319041 ctttctgctt ctgagtcgga gtaccggatt atttatgagg agaaaaacgg aagtgagctt 1319101 atcgtcctcg gtcctcacgg cggcagaatt gagcctggcg tcagtgaact ggtgcgggca 1319161 ttttcggatc gatgttccat ctatttgttt gagggtctaa agcagcgaaa caaccgttcc 1319221 ttgcatctca ctagcattcg ttttgatgag ccgctggctt tagaaaaagt gaatgaccac 1319281 cattacgcat tagcgtttca cgggtattat gatccgaaaa tcccgcatac attggtcggc 1319341 ggggcggatc gtaaaaaagc caagctcatt tgtgagcgtc tgaatgaagc gggttttagc 1319401 gccgagctca ctaatgagaa agaccgcctg gcaggtgtac acccaaacaa tattgtcaat 1319461 cggacgaaaa gagaaatggg actgcaattg gaggtaagca cggcacagcg aaatgcgcta 1319521 ttccgcaatt ttgggtgccg tgataaaagc tacatacaaa acgatttgtt tgatcgatat 1319581 gtggaagccg tcaagcttgg cttttataca taaaactaga cgggacctgc acggttggcc 1319641 tattccttca tacgctgggg ttgtgcgaaa gtgtggggag gaatgattca tgttttatca 1319701 tataaaagag cttcaatatc aagcaaagcc agctcatccc gatccggttt atgcgaaaaa 1319761 acttcaagag gtgctcggcg gccaattcgg tgaaattagc gtcatgatgc agtatttgtt 1319821 tcaagggttt aactgcaggg cggatgctaa gtataaagat ttgttatatg atgtggggac 1319881 cgaagagatt gggcacgtag aaatgctggc aacgatgatt tccaggcttc tggacaatgc 1319941 acccgcggat gtacaggagg atgcttataa aagcaatccc gctattgcag cagtcatgtc 1320001 agggatgaac cctcagcacg cgattgtgtc cggattgggg gcgatggcat cagatagtga 1320061 gggctatccg tggaatgcaa aatacattat ctcaagcgga aacctgctgg ccgattttcg 1320121 cgctaactta aatgcggagg cccaaggacg ccttcaggtg acacggcttt atgccatgac 1320181 cgatgatcca ggggtaagag atatgctgtc atttttgatt gcaagggata cctatcatca 1320241 aaatatgtgg tacgcggcca ttaaagagct ggaggaaaga gaacgggata ttgtcgtccc 1320301 gacgacgttt ccgcgtgagc tcgaaaagca ggaagtctcc tatgacctgt ttaacttttc 1320361 caggggagat gaaagctcac aaggaagatg ggcacatggg gaagcctttg acggccgggg 1320421 tgaattcagg tatatcccgg ctccgattgc gttcgcatct gcgcctcatc ttaaaccggc 1320481 gcccatgtgg ctgcataata cagttccccc aatgtcgaaa tgttaggttc tcttctgggc 1320541 tgaggaatat atcctcagcc cgtatttgat cagatgtttt taccaatatg atataacgct 1320601 ttttcctcag cgacctgcaa gtgctgctga tcgccttcct cgtacgcatt tggccgcttg 1320661 tgagataata aataagcgag ccgcttctga aattgaatac ctgctttacg ccgttcaaac 1320721 atgtcaagcc ttttatcagc aaattccttt gttacccgga ataccgccgc aattgtggcg 1320781 agtgcctggc ttctccattg cggcagttcc atctgcaaca gcataaaggt tggcacacag 1320841 aagtggtaca taaattgatt tgcctggaat tcctgaagct ctctgaagag cttgttcatc 1320901 tgaaaatgat tgcctgcatg ctttaacacg tggcacagct catggccaaa atcctcccat 1320961 tgctcttccc gtgacttttt ttggttcaat acgatactgt acatgccgtc gtatttcacc 1321021 atcatgctcc ccatatcctc aaaatgcacc caaatatcca gatcctttgc gattttcagc 1321081 atgtcaatgt gatgagggga tgtgatgccc agccggccgt ataaattttt aacgtattcc 1321141 tccagatgtg ataagtaatc gcccaattga atactccctt tcgaacgttt gttctgtttt 1321201 tagcgagaaa gaaaagcccg tataggactg gaaggtagtg tagaaatctt tcccttttct 1321261 ttaaaaaata aacacttttt tctttatatc ggtctacttt ttatatgttt tagagaacag 1321321 agaacgattt atttattttt cggtttgcgg tttttctctt tttcttttaa atagttgata 1321381 aattcgatgg cctgctgttt gctttctggg gaaaaatcct gcatatcgcg gtatgcaagc 1321441 tgcaggtccg gatctgagaa catatcgtca tcggattttt tgtctttccc cgttaataag 1321501 taatcagtcg ttacttgaaa gtaatcagcc agcttttgga gtgtgtcgta atcgggttcg 1321561 cttcgcccgt tttcatagtg ggaatatcgt gcccgtgaca caccgatgtg tgatgcgatt 1321621 tcttcctgtg tccttttccc tctgagactc ttcaatctgc cgcctatcat actatgacct 1321681 ctctttttta aactccctac gttacttatg attatagata caaaatgtat caaaataaag 1321741 ttatgataaa aaaagtatca aaaataactt gatgatacag aatgtatcgt ttatacttgg 1321801 taacatccga tacaaaatgt atcaaaaaag atcaggagag tgatcacatg tatccgatcc 1321861 aaatcgtttt tagtgaaaat cccatagatc agcgccatct cggacaatcc ggcggcacca 1321921 tttcgtttac cgcatgcggc cttccggtgt ttcactttga aacgcaggaa cagtttcaag 1321981 catacatgat gttaaaagga gaagcggcgt acaatgaaaa acgataaaag ctatcctttt 1322041 ccgacgtatt cagggttgtt gaattcagaa cattatgaca aaattggccc ggcgttatgg 1322101 ctgtttctct ggtttatcag ctcaacaaca aaagaaatcg aaaaagacgg cgtaagctgg 1322161 ggcatcgtac tcggccataa gccgttaaaa gcgagagaaa tggcggcagt cttcggcgta 1322221 agtgaaaaaa ccgtcagaag atggctggag cttctcgaaa accatgatta cataaaggcc 1322281 gtccgtgcgc catacggact gatgatttcg gtcaagcatt caaaaaaatt cagcttcaga 1322341 tcggacaata ctgtacacgg gagtctaaaa gaacggccat tttcgccgca gacaccggac 1322401 acaaacgacc gtacagatat agataaaaca aacaaatata ctgctgctga tgatgcagtg 1322461 gatcacattg cgaagcggtt tacacaatta cggtcggctc aagaaggacg caccgtgtat 1322521 ccttcctcaa gagattatca agccatcgcc cgcattgttg ccatcggcgt tcctgtcacg 1322581 caaacaatca aatggcttga agaatgcttt caggcttttg aaaaccggcg gaccgccgct 1322641 tctgaaacaa tcaaggcttt tcgctactgc tcgaaattca ttgaagatcg atttttcgcg 1322701 cagcaagcca aaaagaatgc cgcaattcag catgagagga tgaaaaaaca tgacaaaacg 1322761 aacaatcgaa cagattttgg acgagctgag aagagggaga cgtccattac tggcggacaa 1322821 accggccgaa tcagacgcaa gcaggtatga ttgcctgcgc tgcaaggatc agggaggtta 1322881 tctcgtcagg cagaatggcc tggaagtctg gacgatgtgc agctgcatgg cagaacgaaa 1322941 agtgaagcgg ctgctgggtg caagtgagat tacccacgct ttcagacagc tcggcttcaa 1323001 ggaattccgc acggagggaa agccgcaggc cataaaagac gcatttgagt gtacaaaaga 1323061 gtatgttgcc gattatgaac aaatcaagga ttgccgaaaa aacagcattg cccttttagg 1323121 acagcccgga tcagggaaaa cacacctttt gaccgccgca gccaacgaat taatgagaac 1323181 atgctatgtg cctgtcattt attttccgtt cgtggaaggc tttactgatc tgaaaaatga 1323241 ttttgcccta ttagaagcga agctgaaccg gatgaagcag gcggatgtgc tgttcattga 1323301 tgatctgttt aaaccggtta acggcaaacc ccgcgctaca gattggcaat tagagcaaat 1323361 gtattcggta ctcaactatc gctacttaaa tcataaaccg attttgcttt cgagcgagct 1323421 gacaattgaa ggacttgtac gggtcgatga agcgctcggc acgagaatct atgagatgtg 1323481 cagtgactat ttagtgatta tcaaaggagc agcctacgag cttaaccata gattggaggg 1323541 cgtcagataa tgtgtaagct ttgtcaaaca aagaaagtca ttgtggaaca taccggtatt 1323601 ggagttgttt ttcatccatg tccgaactgc cggtccggca ctgacttaac gcctgtcatt 1323661 caaaagctgg agcaaatgct gacagcggga aaagcgaggc tgaatatcta tgattaaaca 1323721 gctgactgct ctaatcgctt tgctgtttcg ggcaaagcga acagaaaaaa acattgaaca 1323781 atggtataag gacgacggga agtgaaagtg ttggcaaaga caaaacaggc agagaaaagc 1323841 cctgcgccgt ggcgtgctgt cccgtgcggg gatacgaaac cgatctatat ttattcagct 1323901 tacagtgaag aagaaaaaga aagatttccg tactcaaacg ggcggctgat tgcagctgta 1323961 tttgacctca gctcttattc gcaaaaaagc aatgcctctt tgatggccgc tgcgcctgaa 1324021 ttgctggaag cgtctaaagc agcacttgat tttctgaaag ggaattctat tcattcaaag 1324081 gagcgtatca ttcagctatt agaaaaagct gaagcaagcg ctgcaccgaa aaggggagga 1324141 aataaaacat gattcatccg aaaaaactgc tgcatatcga ttccgtcacg cttaagagcc 1324201 agctggagga cgggaaaatc cgtgtcatta ttgtggacgg catcaagcaa gaagcatgga 1324261 tcacagaagc gccagagcat ggaaaaacgc tcgtcgaaac aagaaagggc gatcttgctc 1324321 gtgtggaatt tgaaatcggc tacaaattaa attaaagcga aaacagaata cgtccaagac 1324381 ggaaagcctg cggacactga tcaactgcac agcatttgtg cgttgattgg tgtccgtttt 1324441 ttatttgcca aaaatgagga ggatcataga atgcaagact tactatttga atataaacgc 1324501 acgctcaaac aaacaagaat acaatataaa ccgctcgctg aggcagatga atccgtgctc 1324561 tcagctgaag agctgaagga taaaaaaatc atcagaaata tgattactga tcttgaatat 1324621 gtaacagaat ggcttgaaaa aggaaggcag cccggcatca gacgggcgat tgaccggcgt 1324681 gatgtttacc agcggctgat gatcaaggac ccgagaatca tcgaatcatt ttccagcgct 1324741 atgatgtttg agccggacgg acaggtatca gaagaagaca gagatagaat tcgagaagca 1324801 ttagccctgt taacggacag agaaaaggaa atgtttttgc tgcataaggt agaatgtttt 1324861 tcttatgaac ggatcgccga tcttctcggc gtaaaaaaat cgacagtgca aacgacgatt 1324921 aaacgggcga gtttaaagat gcaaagacag caggaagaaa tgaatcgatc acttgcctga 1324981 aagcttgtca tacgtttgcc acctataagt gaatagagca tgacactaag cggctggctg 1325041 atcagccgct tttatgaata aacaaccatg ctggaggtgg cggtgatgca gtagcatgaa 1325101 aacacaacag cgcgaacaag cattagcaat ctatcaacaa catcaaggaa agatcacaaa 1325161 tcgggcgatt gcggacacaa tcggtgtttc cgcgaaaaca atcggcatct ggaaaaaaca 1325221 agacaaatgg aaagaggcgc tgttttctgc gtccaaaaac gaacaaaaac agcgccctat 1325281 aaacaacgat gaattaaatg aacgccagcg gctgttttgc ctgtattacg tcaaaagctt 1325341 caatgccaca cagtcagcaa tcaaagcggg ctattctccg gacagcgctc atgtgacggg 1325401 cagccgactc ttaaaaaacg aaaaggtcgc tgctgaaatt agacgcatta aaaaagaaat 1325461 ggtcaatgaa atgtttattg aagcgatgga tgtgctgcag gtttatatca agatcgcgtt 1325521 tgcggatatt acggactatg tgacctttgg aaaaaaagag gtccaggctg tcgggaaatc 1325581 gggtccgctg tttgatgaag atgataatcc gattatgaag gaaatcagct ttgtcgatgt 1325641 caaagactcc gggctcgttg atggcaccat tgtaacggaa gcaaagcttg ggaaagaagg 1325701 cattgccatc aagcttgcag ataaaatgaa ggcgcttgag aagctatcct tatattttga 1325761 tttgtttcca gatcaattta aacaaaaaat tgaaaatgag aaattgaagc ttgccaaaca 1325821 aaaagcggag aaaacagatg acagccagga gccgattgaa attatgatca aacgaaaaga 1325881 gcgcaagtca tgattgtaaa agaaatcaac cctcatttcg aagattacgt gttcaattgg 1325941 gagcagacgt accagtttct tgtcggcggc tacggctcat ccaaaagcta tcataccgca 1326001 ttgaaaatcg tgctaaagct gctgaaggaa aaacggacgg cccttgtgat ccgggaggtg 1326061 ttcgataccc atcgggattc gaccttcgcc ttgtttcaag aggtgatcga agagctcggt 1326121 ctcacaaagg ccgtggcatc tctttcttcc ccgctgcagc tgcgatttca caatggcagc 1326181 cggatcatgt tcaaaggaat ggacaatccg gcaaaattaa aatcggttca taacatttca 1326241 ttaatatgga ttgaagagtg ctcagaggtg aagtatgagg ggttcaagga gttaatcgga 1326301 cgtcttcgcc atcctgagct aaagcttcat atgatctgta ccaccaatcc cgtcggcacc 1326361 tccaattgga cgtataggca tttttttcgg gatgaacgca agaaacggtt tgtgctggat 1326421 gacagcgaac tttacgaaaa gcggacgatt gtaaagggag atacgtatta ccatcattcc 1326481 accgctaacg acaatctttt tctcccggaa agctatgtga aacagcttga cggactcaaa 1326541 gagtatgatc ccgacctgta ccggattgcc cgaaaaggac gattcggcgt caacgggatc 1326601 agggtgctgc cgcagttcga ggtactcccg catgatcaag tgaaaaaatg tatcgcagcc 1326661 atcagcaaac caatctttcg tacaggtatg gattttggat tcgaggaatc ctataatgcc 1326721 gtcgtccggc ttgctgtaga tcctgaaaaa aaatacctct acatttattg ggagtattat 1326781 caaaataaaa tgacagatga taggacggct gaggagctgc gtgagtttat tgagacacag 1326841 gaattgatca aagccgactc ggctgagccg aaaagcattc aatatttccg ccagcagggc 1326901 tttcggatgg ttggagccag aaagtttccc ggctccaggc ttcaatatac caaaaaggta 1326961 aaacggttca aaaaaatctt ctgttcggac cgctgtgaaa atgtcatcta tgagctcgag 1327021 acacttacgt atgccaaaga taaaaacgga gctctgattg aggatgaatt cacgattgac 1327081 ccgcatacgc tttctgccat ttggtatgcg cttgatgatt atgaggttgc tgatatgaaa 1327141 gagacagcac acaaacgaat gcggccgaac cgagaaagga ggaggtcata aatcatgcac 1327201 aaccaaacag tcagagcaac tgtatttaaa gccaatgccg cggctcctca gacaaagcaa 1327261 atctatgaag atgacttttc tgagctgtac ggagaggaca ttattgctcc gccctataat 1327321 atcatcgagc tcaaaaccat tgccgaatac tcgaccattc ttcagcaatg cattgatgcg 1327381 tacagagtga atattacagg ctttggattc gatgttgagt acacatttga tgtcaacgca 1327441 agtgatgtcg atcaggcaaa aaagaaaaga gcggaaaaag actgggccag actcgaagcc 1327501 ttttataaat gtcttcactt tgatgaatca gctgaaatga ttttaggcta tgccatcgaa 1327561 gacagagaaa aaacaggcaa cggatttatg gaagtgcttc gcgacggggc gggaaaacct 1327621 gccggcatcg aatatttaga tgtgaaatat atgcgtgtat gcggagcagg cgagcctgta 1327681 gaggtttcat ttgtatatga agaaaacggg aaaatgaaaa ggatcaaaag gcaaaaacgc 1327741 ttccgaaaat atgtgcagat gatcaatgga aagaaagtat tttttaaaga atacggcgat 1327801 ccgcgaaaaa tggatattcg cacaggtgaa tatgtaaaca cattggcaga gaagtatcaa 1327861 gcaaatgaag ccattcacct caaaatcgga agcggcgtat acggtgtacc ccgctggatc 1327921 ggcaatattg tcaatttata cggggcccga aaagcagaag agctcaattt tatgtatttt 1327981 aagcaggggc gtcacgtccc cgctgcgatt acagtggaaa acgggatgct gtctgaagct 1328041 tcttaccggg agctgcagga atacatgaat gatcttgaag gcgtggagaa cgcccataaa 1328101 tttctcctga tcgaagcgga aggaatcgca aaagaaaagg atctccacgg aggcgaggat 1328161 attacgccgg tttccgtgga aatcaaatct ttggctgaaa ttctccaaaa cgacgccttg 1328221 tttcttgaat acgatgaaaa aagcagaaat aagctgcgtt ccgcgttccg tctccccccg 1328281 ctgtatacag gcgaggccca ggaatacaac cgggcgacag cggatactgc tagaaaaatt 1328341 acggaggagc aggtttttca gccggagcga aaaactctcg tgaataaact gaacacgctg 1328401 cttttgccgg agctgaatat ccatgacgtc aggctgacat taaaaggacc ggactttcgt 1328461 gatccgcttg agattgcgaa ggtgctcggt ccttttatta cagccggagc agtctcgccg 1328521 aatgatttac gcgaccttgc cggacgggtg cttggcaaaa cacttgagga gtggccggag 1328581 gacatttata aacggcctgc aggacaggat gcggaaaaga caaacctggc tgcgctcatg 1328641 caggagctga aagaaagcat cgaagatatc aaaacgtcct gaagggaggt gaatcaagca 1328701 ggtggcgcga gaattaagaa atgccaaaat cagctttgtc agttatgtgg acaaggcggc 1328761 taaccagaca gaatttttct ttacgaagtc agccgaacct ccgtcatttg aaaaaaaggt 1328821 tcggctgttt acaaaaagtg agcaggatga acaaaagctc gtgtacggaa tcgtgtatga 1328881 gcctgatgtt cctgatgccc acggcgattt tatgaccgcc gaggaaattg aaaaagcggc 1328941 gcacggtttt ctcgcggagg cacgggagat tgatatcaat cacagctttg agggcggaac 1329001 cggcgtcgtg gtcgagtcct atgtggcgcc cgatgatttt atgatcggat caaagcggat 1329061 tacaaagggc tcatgggtac tcgtgacaag agcgtctgac gaggtgtggg aacagattaa 1329121 ggctggaatt atcaccggct acagcatggc tggcactgca gatgtgtatg aagaagaacc 1329181 ggtcgaaaaa gcagggttct ttagtgtatt caagcaaatg cttgctgaca aaacagggaa 1329241 ggagactgaa gaaatgagaa aagaagacat gaaagaatca ttcgagcatg cgctttaccc 1329301 tctgctcaaa cggcttgagc ggattgaaaa aaacacagac acggaggaaa agccggagca 1329361 gacgggtgat gacgagcgtc tgaaaaagct cgttgaagac atgcttgccc cgctgatcga 1329421 acgcatcgag gctttggaaa aagcgcgagg cgcgtctaag cagacagcgg acgatacggg 1329481 cggcaataca gagcaagtca aaaaatcaat ctggagcgga ctgctgtaaa accagtcaag 1329541 gaggaggaaa tcaattgaga aatcaagaga tcattcggaa agcggaaatg tcgctttctg 1329601 ctttaaaaag cggcgggctt atgaaccctg cgcaagcatc ggcttttatc cgcatggtgc 1329661 aaaacacgcc gaccattttc agtgaatccc gcgtgattca aatggaaaac gattcgcaaa 1329721 aatttgaaaa aatcggcttc ggccagcgta ttctgcgggc tgcgcaagaa ggaaaagcac 1329781 tgtcaaacga cgagctgaca gttccaacga caagcactgt ccagctgaac acgaaggaag 1329841 tcattgcgga aatcaacatt acgtatgaca cacttgaaaa caatattgaa aaagacggcc 1329901 tgcagcagac aatcatgcaa attttagcag agcgcgcagc agttgatatt gaagagctga 1329961 tcgttaacgg cgatacagca tcagctgatc cgtatctggc acagctggac ggcatccgta 1330021 aacaggcggt ttcccatatc gttgacatga acggtgaaga actgtccaga gcgacattca 1330081 agaagggctt aaaggcagtt ccgccgaaat atttgcgcat ccctcaggaa ttcagattct 1330141 atacgtctca cggcttagaa gttgaatgga aggaccgcgt ggcagaccgc cagacaaacc 1330201 ttggggacca agctgttcag ggcggcttgt caacagcatt cggcgtaccg gtcaaagggg 1330261 tatccaatat tcagccgtac acagtcggtg agggagacgc gcaatatgac gcttctgata 1330321 tcattctcac acatccgaaa aatatcattc tcggcttctc ccgcaatatc cgaattgaag 1330381 tcgacaaaga catccgctcc cgtaaattca ttattgtctt aacggccaag ctggacagca 1330441 agttcgagga agaggatgcc tgcgcgaaat taattaacgt aaaagaataa tagaaacgag 1330501 gtggtcagct catgctcatt gaaccgactg acgtagcttc ctattcggtc tatgatcggg 1330561 tgaaaaacag gccggaagag ctgctggcgc aggatatcat cgaggcggaa gcagaagcgg 1330621 ctctcatcac gggccaccgc tttgaagaca gcttgtatga tccgctgccc ggcaaggtga 1330681 agttggcttt agtaaagctt gcccagtatt ttgcgcttgt caacagcgat gaatctgcct 1330741 catcaagcta tcagtatgag aaaatggggg attattccta cacggtttcc ggagaaggca 1330801 ggattcagcg gcctgaggtg tatcatttgc tcgaagagtt tattaagccg ggctacgtcc 1330861 ctgaatcctc cagactgaag gtgagatctt tatgagctac aggcagatgc tcattcaccg 1330921 ctgcgatatt tatcatgaag cagcgcaagc gccgtctgca ggccgatttg ggattccggc 1330981 agacaggctg cagccggtga tttcatatcc ggatacaccc gatgaacaag atgtcccttg 1331041 ttattttacc gaaaaaacac agcagctgat tcaggaggag ccggatcaaa ctgtatatca 1331101 tagctttctc gtccattttc cgttgtcagc ggacatccgc gtgaacgata aaatcatttg 1331161 ggagaatcat aaatatatac taaagctgcc gaaaaggatc agacatcatc attgggaggt 1331221 cgtcgcagtc agggatgaaa gcctatgaaa atagcgggat tgaaacagct gaacacggca 1331281 ttaaaagaag cggcttcagg cggtttttcc agacaggcgt cccggtggct tgaggagtgc 1331341 gggcaagatt ttctagagat cgtccaatct gaactcatca gcacacaaac gattgataca 1331401 gaaaaactgc tcagttcctt tgagaaaggc gcagaggaca atctctggat tgtgcaaagc 1331461 ggcgggcttt cgcttgaggt ggggacacag cttgattacg cctcatttct taatgacggc 1331521 cattggacgt caaaacaaga tgtgagatgg gtgccggggc gttttcaagg ctcacggttt 1331581 atttatgatc cagcggcttc aacgggaatg gcgctcaaga gaaaatggat accgggcacg 1331641 ggctactggg atcatgcact gcttttatat gaacagctgt ttgaaaaatc gctggaaagc 1331701 aaactgcgcc agtggctgaa gaagctgtaa aggaggagca ggatgaacag tgaaacagga 1331761 tcgatcatgg cgtttttgta cagccggtgg tctgttccca tttatgaacg cgagcttcct 1331821 gatcactttc aggtgccgtc gttatatgtc ccgccaccat ctgttttcga ggaaacagat 1331881 acggtctcca catttaaaaa aacctacagt ctcaatgtga aactgtttca tctggactcc 1331941 gttcaggcgc tggatgaagc ggacaggctc gcggatgcca tcagagaagc gagaaatatg 1332001 attccgctgc tgagtgaatc cggcgagaag acgggggata tggttcgcat ctcccaaatc 1332061 gagacaaggg taggggacag gggcgaggcg gccatggtga tcaggtggag cagcagatat 1332121 tattatcaca aaacagaaca gcctgtctta caggatatcg acatgaacag cggggtgaaa 1332181 taaacggtgt caaaggacaa acaacagaag aaggctgtac atacaaagag ccgggaagct 1332241 ctatttgata cagcggattt gattaagcac gcgaaggaac tgttcggcgt taagccggat 1332301 attcttcagg gggctttatt tggcgtggat caaccacgta tgacgaaatc agaagccaac 1332361 caattgattc aaacatttct aaccaaggag gtcatgtcat catgaatggc ggaacattta 1332421 caacaggcaa agaaaaagaa cgtgcaggca tttattttaa ctttaaaacg acggcacagg 1332481 agcgggtatc actcagtgaa cggggaacag tcgcacttcc ggtcgcctca agctggggcg 1332541 aagcgaaaac gttcgtctcc atttccagcg ttgaagacct aaacaaaaaa gtgggcctca 1332601 gcattgatga cccgtcttta ttgctgctgc gtgaagcgaa gaaaaatgcg aaaacggtat 1332661 tgatgtaccg tctaaccgaa ggtgtccgag cgtctgctga tattgctgaa ggcgtcaaag 1332721 caactgcagt atatggcgga acaaaaggaa atgacattat catccgcatc aatcaaaatg 1332781 tgctggatgc taattctttc gatgtgacaa catatatgga cgaatcagag gttgataaac 1332841 agactgtcaa aaaggctgaa gaattaacag ctaacggcta tgtcactttt accggaacag 1332901 gcgatctttc ttcaacgatt cctctcactg gatcagaagg agacactgca gctgagacgc 1332961 tgaatgcatc cgcgggcatc cgtttatccg gcggtacgga taaagcccct gtcaactccg 1333021 actatacaga tttcttagcc gcggctgaaa cggagagctt tgatgtgatt gcgctgcctg 1333081 ttgcagaagg tgaccagttg aaagcgacgt ttgctgcttt cattaaacgc ctgcgcgacg 1333141 gccaaggaca aaaagtgcaa ggcgtcacag ccaattatgc cggtgattat gaaggcatca 1333201 tcaacgtaac cgagggtgtg ctgcttgaag atggcacgga agttacaccg gacaaagcaa 1333261 cagcttgggt agctggagcg agtgcaggag caacctttaa ccaatcactt acatttgtag 1333321 agtacgaagg cgcagttgat gtgttacacc gccttgacca cgatacgatt gttgaacgtc 1333381 tgggtaaagg tgaattttta ttcacattcg acgcccgtga taaatccgtc agcgtagaaa 1333441 aggatattaa ctcactcgtg acgttcacag ctgagaaaaa caagaaattt gcgaagaaca 1333501 aaatcgttcg tgtcctggat gctgtgaata atgatttaac acgcgagctg aaagccttaa 1333561 ttaaatcaag aaaaggcagc ggaagcgata tcccggcatc tgaagacgga ctgcagtatg 1333621 taaaaacgat gatcacacaa tacatgacaa cgcttcagga cgcaggcggc atcactggct 1333681 ttgattccga tgaagatatc acaatttcaa tgaatgaaga tcgtgacggc ttcttgattg 1333741 acctggctgt acagcctgtc gacgcagcag aaaaattcta ctttaatgtg gaggtaaact 1333801 aatatggcat taaaagcaca aaacacaatc tcaggaaaag aaggccgttt attcctcgat 1333861 ggtgaggaaa tggcacacat caaaactttt gaagcaaacg tcgagaaaaa caagtctgaa 1333921 gtcaacatta tgggccgccg catgacaggc cataaaacaa caggggcaaa tggaacaggg 1333981 accgcgacgt tctacaaagt cacatcaaaa ttcgtgctat tgatgatgga ctatgtcaaa 1334041 aaaggcagcg acccttattt cacgctccaa gctgtgctgg atgatcaatc ctccggccgg 1334101 ggcacagagc gagtcacgct gtacgacgtc aactttgact ctgccaaaat cgcaagcctt 1334161 gatgtcgatt cagaagcgtt agaggaagaa gttccattta cattcgaaga cttcgacgtc 1334221 cctgaaaagc tatctgacac gttttaatca aagctgaatc agcccatacg cagacctttc 1334281 tcagaaaggt ctgtttttta aagatgaaac caaacaatag acaagggagt ttttttacat 1334341 gagcgagaag aacgaaaacg tatatgatct ttcctttttt atgccgggaa aaacaattga 1334401 agctgaggaa atcaaagtgc cgatctcaaa gcgttttgtt gataaaaaag ggaatgtcat 1334461 tccgtttatt ttaaaaccaa ttactactga acggattgat gaattagaga aagaaaacac 1334521 cacatttaaa aatgtgaaag gccgcggccg tgtcaaagat ttagactccc agcgctttta 1334581 tgcgagaatt gccatcgaat ctactattta tcctgatttt cgttcaaaag atttaaggga 1334641 agcatacaaa actgcggatc cggtagaagt tgccaaacgt gtattatctg ttgggggaga 1334701 gtatgcgaac tggctgaata aagcaattga aatcaatggt tttgaagatg atcttgaaga 1334761 tctagaagaa gaagcaaaaa actagtaaag gatggcgata aggaagctgt gtatttgtac 1334821 tatgcaatgc atgagcttca ttactcgcca tcccaacttc ttgaattata tgaagcacca 1334881 aaacatttta aagctctttt atttgggttg ataggttata agctagatct attagaaaaa 1334941 gaatcaagga gaggagggaa ctaatatcgc aaaattaaca gcccgttttg atctcgaaga 1335001 caaggtatct aaaaaactaa aacggataca taaaggattc caagaggtcg aaaaaaaagt 1335061 caaaaccatt aatcggcaaa tcaaaatcag tatcagagcg gaagatcagg cattttaccg 1335121 gctgagaaaa ataaacgact atatcatttt gaaattcgcg aaatcgcttg aaattaaagt 1335181 tgtacttgat gaccaagtca cttcaaagct tgatgcaatt gaaagaaaac ttaaacggct 1335241 gccgaaagaa acgaagctga ctgtctcttt ggtagatcgg acagcagctg cgtataaaaa 1335301 aataaagaag atgctttcta atcaaaagct atcattcctt ttgattccag atgacaaggt 1335361 tacttctaca gttaaaagga ttatcggtta tattaagaaa aatttgaaaa acggatacac 1335421 agtaaaacta aaggtcatcg atgaaatcac caaaacagtt aatcgattaa cagcccttct 1335481 aaggaaattt gaaaaaacct attatgtaaa agtggttgtt aagacaaaaa tatcagacaa 1335541 aatcaataaa aaagaaagcc tgattaacaa agaaacttct aagaaagaat cagacaaatc 1335601 ctcagataaa ggctctgata aaaactcaga tcaaaaacct ggatgggtcg gaaaaataaa 1335661 aggctggctg aaggattggt ggacaaaatc agcttggcct tggatcaaag atacgctcaa 1335721 tgaaataggc aaagcttttt tggatcgttt caaagagaga ttgatagaaa agctgaaaaa 1335781 tgatgtgttt gataagatca ttgataaaat tctaggacca caaaaaaagg acgattctgg 1335841 tgaaaattct gacacagata aaaaagtcct taaccgtaat acaggaggaa attgttgctg 1335901 tgactgctgt gaaggcggta tcagcccggg cactaaaaat aaaaaaacct atagaaaaaa 1335961 gaaaagtccc acaaaggctc caaacagaac actcaaggtt cctggagagg tgataagaag 1336021 acgccagagc ggcacacctg ctgaaagtgc acctaggacc tcgggttcca agttaaagaa 1336081 ctggcttgga ggcttaaaat cgctagggaa ggattcatct aaactaggta aagcgttcag 1336141 aggaatggga aaggctgttc catacgtagg atctgcttta gcagtgtttg atttagctgg 1336201 aatcaataaa gataatgctg gcgaaaaggt tggttcaatt ggaggacgta ttgccggagc 1336261 ggaagctggt gcaacagccg gagcggaagc tggtgcaacg attggatctt tcgttggtcc 1336321 ggaaggtaca gcaatcggcg gcgcaatcgg cggaattggc ggcgggttag taggcggaat 1336381 cggcggcgaa gaagcaggta agaacattgg taagatgttt gatacttcta agttaaagga 1336441 gagcataagc aattcactat ttaacaaaga gtggtggagt ggaaaatgga actccatttc 1336501 tgatactgcc aatggggcta ttacttggat tgaagataca tggagtaaag tttcaacttg 1336561 gtttgaccag tatgtgttta cacctatata taatgttgct gtacctgtaa ttaattttat 1336621 agtaggattg tttgcctatg cctgggatgg catattggca gtatggaaca ttgtctaccc 1336681 gtggtttaag gataacgtgt gggatccaat aagcggagca gttactaatg ttgctacaac 1336741 gatatggact ggattgtgca acgcctggac ggttatttca ggcatatggt ctactgtttc 1336801 aacatggttt atggacaatg tgtggaatcc tgtaagtgaa gccgtaacca ctgcggcaac 1336861 atggatttgg agtaagatca atgatgcatg gacaataatt tccaatattt ggacaggagt 1336921 atcgaattgg ttttatgata atgtatggaa cccgatcgtc aaaaaagtag aagatattaa 1336981 aacttcaata aaagaaaaat tcgatgatgc aaggaaattt tttgaggatg catgggatgg 1337041 aattgaaact tggtttaatg aacatgtgaa agatccattg gttaaagtat cagagaaaat 1337101 tgctgagaaa tttcaatggc tattcgattt aaaagattca gttggtggtt tcgttgcaaa 1337161 agtaatacac aggggggaag aagttactca cctcaagaaa aaaccaatca aaaaggattc 1337221 gaaagagaaa aaaactagtt ccaaaccaac tactaataac atttttgctc aatctccatc 1337281 aaataataat atgactgttt ttcaacaagc actagatcag aacgccacag gcggctacat 1337341 caccaaacca accatctcgt ggatcggtga agccggcaag gaattcgtta tcccggttga 1337401 taacaaccga ggccggggga agatgcttct ttcacaagcg gcgtctaagc tgggtatgca 1337461 agttgtagac gacatgggcg cagcttcgtc ttctggcgga agtccagcat ctgtttcagg 1337521 aggagcagct gtcagtcctc tatcaggcac agcctcccca gtaatgaaca ctgcaaatct 1337581 tacaggccaa gcgtccacac tcggacagca attttcagaa ggctttggta aaggcatcag 1337641 cgatcagccg gtcaaaatgg aagactggaa aaagaaaaac atcaatacac catttacaca 1337701 aatgatttct gcttcaccaa attacggtaa acaaatggta agtgggtatg ccaagggcca 1337761 aagcggcact gcaaccggaa cagacggctt tttgcaatca aaagttaaaa cgccgttcca 1337821 agccactgtg agcaaatcgt cttcatgggg cacaggaacg gtcaaaggct ttgcgcaagg 1337881 acaaaattca acccaaacag ggactgcaca gtatgtgagt acacatgttg acaaaccgtt 1337941 cctgcgttca aaagacacat cgaacagctg gggctccggt ttgattggaa actttgtgac 1338001 aggcatgaat tctaaatcca gtgaagtaaa acaagcagca aaggatatgg ccaagagagt 1338061 ggagcaggct ttccgtgaag aattagatat ccattcacct tctcgagtca tgatgagctt 1338121 ggggcgtttt gcctctgtcg gtgttgtaaa aggactggat tctgtcgatg tgaaaaaata 1338181 cgcagaaaaa caagccggtt cattggcagc tgcttattcc ggaatgggtg cagtaggggg 1338241 aaatgtgaaa cagtggctta tggcagcaat aatggccaca aagacaccat tgagctggct 1338301 ctcgggatta atgacgattg cacagtatga atcagggggc aacccgaact ctattaacct 1338361 gtgggatagc aacgcgaagg cgggaaatcc atcacaagga ctcatgcaga cagttccaac 1338421 cacatttaat gctcataaag caccgggcat gggtaacatt agaaatccga ttcacaacgc 1338481 tgctgccgcg atcggctata tcaaaagcag atacggctca attgataatg tacctggcat 1338541 taaaagcctg aaacgtggcg gtccttatgt cggttatgca aacggcgggc tgatcacgaa 1338601 agaacaaatt gcccgtgtcg gtgaaggaaa caagcgggaa tggatcatcc cagaggaacg 1338661 gggcatccgc ggtcgctacc ttcttcagag agcggcacag gctcttggta tggaagtgac 1338721 agatccgtct caatcccagc agtctgagct ttcttcagga caagtttcag ctgttacctc 1338781 ggctagccgg ccgactgcag cggtttctgg atcaaaagag atttatattc aatttaacgg 1338841 tgaccagcac ttccataatg gacaagacgc cgaaagccta gcggcgaaga tcaagcaggc 1338901 gcttatagat gaactgcaaa aggatatcaa tattggaacg aagggagtcg ttgcatttga 1338961 ctaaatccgt atatgaattt tggatttcac aagggaagga caagctgcgg ctccccgttc 1339021 ttcccgacca gctgagtatt tcaaatacag ttcagaatga gacggttaaa gtagccaagt 1339081 tcggtgacct tacatttatt gacgagcagg gagcgaaaga aatttcgttc tcttcttttt 1339141 ttccgaagaa atacagtccg atagcagaat atcaaaactt cccgtcgccg gaaaatgcga 1339201 taacaaaaat tgaaaaatgg atgaaggcca aaaaaccggt tcagtttttg attacgggaa 1339261 ctaaagtgaa tttaacatgc agtattgaag gtttttccta tagcgaaggc cagcaggata 1339321 taggtgatcg ttcctttgat attcaattaa aagaatacaa aaccgcttcc ccgcggaaaa 1339381 tcaagcagaa gaaaaaaaca aaggcaaaac gtccgtcgaa ggctgcgccg aagacgtaca 1339441 cagtgaaaaa gggagacacg ctatgggaca ttgcaggcag attttacggg aacagcaccc 1339501 aatggcgcaa aatttggaat gccaataaaa cagcaatgat caaacgaagc aaacggaaca 1339561 tcaggcagcc gggccactgg atttttcccg gccaaaaatt aaagataccg caatgaaaca 1339621 ggtgatgtat gatgatagaa ctgttcgtca ttaaagacac agagtggctt gagctggttg 1339681 cagaaagcgt atcgcttgaa ggccatcgtt atcaggcgcc gcgttccatt gaagcaacca 1339741 tcgtcaccaa gcagggcgac cagacgtatt acagtgtctc agaaggagat acggtcttgt 1339801 ttaaatggaa gggaaaagag ctgtttcggg gcattgtttt tgcaagaacc ccggacgagc 1339861 atacgcttgc cttcagcgct tatgacatgc tgcagtacct ggtcaaaaac caggatatgt 1339921 acgtgttttc caatcagcgg gccgaccaga tcatcagaag gattgcgagt gacttccaga 1339981 taccgacaac ctcgatcgca aacacaggcc atacgatcaa aagtcttgtc attaaaaatg 1340041 atacgacatt gtatgacatc atattaaaag cgctgaaaca gacgaaaagc cagacaggac 1340101 gacattacca gctgtattcg gaaaaaggaa agctcggcct gcgcgcttgg ccagatccgt 1340161 cagaggtatg ggtgcttgaa acgggcgtca atatcacggg ctaccaatac agcacttcta 1340221 taaacgacac tgctactcgg gtggtgcttc gccggcagaa ggacaataag acatataaag 1340281 cctctgccaa ggacagttca ggcttaaata aatacggtgt gcttcaatat acggaaacgg 1340341 tcacagatga catcaaccag gcacagcttc agcagcgggc agatgtacgc cttgctgaaa 1340401 aaaagggcgt gaaaaaagaa ctgaaaaata ttcaggcagt gggcatccca gaagtgcaga 1340461 gcggcttgcc tgtctatatt tcgattccgg aggccggcat caagaaaacc tattgggtag 1340521 atacggaccg gcatgaattt aaaggaacga aacatacgat gacgatcgat gttgtcgaaa 1340581 agaatacgat gccggaagga gtttcctgat gagattaagt gaggctataa aacatttggc 1340641 agtcggcgca gttgacgctg agtctccggt agaactgctc ccggctgaag tcgtttcggt 1340701 ttctcctgtg gaaatcaaat taaaagaaaa cagcaaactg atcataccgg aagacgccat 1340761 cattatccca aaacgaatgc agtccggagg agacgatgca ctcgagccgg gggatcgcct 1340821 catgaccgcg gctctgactg gcgggcaatc gttttttatt ttagataagg tatagacaaa 1340881 ccgcttcagt acgaaggggt ttttatttag catgtaaaag gagtgggcaa catggccctg 1340941 acaccagaag tggagtttga agatattgaa gttgagagcg aagtcattga aacctcgcaa 1341001 acgtacaaaa tagattttga aaacggaaga attacgaatg agctgattac cgggcttgaa 1341061 gcgatcaggc agttcgtgta tatcgcctta cagacagaac gctatgcata ttccatatac 1341121 agccataatg tcggaaacga gcttcaggac gtgctgacag atcatgagac gactgatgcg 1341181 tataaaaaga tggagattcc gagactgata gaagaggcgc tggtttatga tgaccggata 1341241 tctgctgtaa cagattttga gattgaaaaa caaggcgacg cgtttcatgt gtccttcgtg 1341301 gtggagacgg atgaaggaac gcttgagatt gaggaggtga ttggcgaaga tgtttgaaga 1341361 tcagactttt gaagcgatta tggagcgtat gctgaacagc atttccgcag atattgacac 1341421 aagagaaggc agcgtcattt ataatgcgtt agccccggcg gcggccgagc ttgcgaagtc 1341481 ttatatatgg ctggatactg tgcttgagct agttttttct gataccgcac aaggcgaatt 1341541 tttagacagg cgtgcagcgg aagcgggaat tgaacggaca gccgcgacaa aggcggtcag 1341601 agcgggagag tttacatctg gagttactat tcctgtcggc tcccgctttt acgtggataa 1341661 tctttatttt caatatacgg cagacgggac gctcatctgt gaaacacctg gtgaagcggg 1341721 aaacgccaat ctgaccggac gcaatttact gtcattggat accattcccg gtttagaaac 1341781 ggccattgtc aaagaaatcc tgattccggg gcgcgaggaa gagggagatg acagcttgcg 1341841 agaacggtat tttacaaggg ttcggcgtga ggccgtcagt gccaataaaa tgcattataa 1341901 agagtgggct gaggaagtgg acggtgtggg aaaggcaaag atcttcccgc tttggaacgg 1341961 tgaaggcacg gtcaaaattg tcgtcaccaa tgcgaatctt gagcccgctt ctcctatttt 1342021 aattcaaaaa gtgaaagatt atatcgaccc tgaaccagga cagggagagg gacaggcgcc 1342081 aatcggagcc gttgtcacgg tggaaagcgc ggtctggaag gaagttgaga tttctgccga 1342141 agtgctgcct gagatcaatc actcaattga tgaagtgaag tcggaaattg aggaaggcgt 1342201 tttaaacttc tttaaaaaaa tggcgtttga agacaacgtt atccgccttt ctcaaattaa 1342261 caatatcgtc tataattcac catcagtcag tgactactcc aatattcaaa tcaacggcac 1342321 gtctgaaaat ctggtgctga gcgacgtgga aattcctaag cttgggcagg tgaagatcat 1342381 tgagcaaaca agatgacatg cgagcttatc tgccgccgtt tctcaccagc cttaaagaaa 1342441 tggccgagct gctgaaagcg gaagcgcctg agtttgataa acaaaatgac agcatatttg 1342501 atctgacgga tcagttattc gtaccgacgg cgacttgggg gctcagccgc tgggaaaaaa 1342561 ttttaaacgt cccgcgggaa tcaggcgaca ctgatgagat cagacgattg cggctcattt 1342621 ccaaaatgtc gaacatcccg ccaatcacat acagggccat tgagcaggcg gtaaaccgtt 1342681 tcttgaaaaa cccgtctgca caggtccgcc tgcttcccgg cgaataccga tttaacgtcg 1342741 atatcaatgt tgatgacctc cagcacatga atgagctgat cgaagcgata gaaaacatga 1342801 aacccgctca tttggcgtat acgctcagag gcggattgaa tgagacgctg cgaatcaaag 1342861 atacagtcat cctgaatcac cgcagatacc gaacagccag tgagctcaag gtcggttatt 1342921 ctgtcactct taacaacaat gaggtggttt taacttgatt tcaaccatat acagagaacg 1342981 cacagcggct gatctaaaaa gcagaatcga tcacgtgctg ctcaacggcc aaaaaacaga 1343041 aatagtagag ctcgccattg acggtgcgac agtcaccgtt ctgacaaaac gtgaggaaga 1343101 catcaagcat attgaaacgg tacaaatttt tgacgagctg ggcaatgtga tcacagagag 1343161 aaagactgac ctggacgtca gcgaaaacag aacactcgat ttcagattta cttttgaggt 1343221 ggtgtaaaca tggcatacga agaaaaaaca gactggcttc cggacgaccc aatcaacgaa 1343281 gatgacgtca accgctggga aaaaggaata aaagacgccc acaccgacct ggctgcccac 1343341 aaaaacgaca tgaacaaccc ccacaacaca acaaaggcgc aaatcgggct ggggaatgtg 1343401 gataatgtgc agcaggcttc aaagacggaa tttaatgaac ataatcatga ttcaacccgg 1343461 catattacat cagtagaacg tgatgaatgg aatgcgaagg aaacacctgc cggagcccag 1343521 tataaggcag atcaagctga agcaaacgcc aaagcatata cagacaattt tgctgcacga 1343581 agagataatc ctaaccaagt aacaaaagca caggttggac ttgggaatgt cgaaaatgtg 1343641 aaacaagcct cactagcaga ttttgatgct catttaagca attctaaagt tcatgtatct 1343701 gaaggggaaa gaaacaaatg gaatgctgcc caactaatta aacttactgg agacgacggt 1343761 aaaagaatac aactccaaga cggtacagat attcttacat tatcttctgg attttattgt 1343821 gcagttggtc agtcagttgt aaacaacccg gtggaaggcg atgcagcttg gtataactac 1343881 gatattgtag aaggcggttc aggaaggaaa acaatagtag cttaccaaag ttggggaagt 1343941 atgatgtgga ttggaatggt tcacactgat ggagaattta gaggatggaa acaaattgca 1344001 acaacagatt ttatagatag agttcaaaca gaattagatc ttcatgaaaa tgataaaact 1344061 aatcctcatt cagttactaa acaacaagtg ggtctcggaa atgttgagaa tgttaagcag 1344121 gagacacctg atggtgcgca aaaaaaagct gatactgctt taaaccaatc aaaagattat 1344181 actaacagca cggcctttat tactagacca ttaaattcaa taaccgatgc aaatgattta 1344241 aatcttccgc ctggcactta tcgtttagac actaattaca tgaatgcaaa tccagttttg 1344301 caaaatcaat ttccattaaa tgataacaga acaggtttat taattatcta cccctctgca 1344361 aataaatggg ctacacgtca agattggttt agcatctcta cgaaaacact ttatacaagg 1344421 gtagcagtta atggtactga ttattcaggg tggtatatat tagagaattc ggaaggttca 1344481 caaaataaag cggataaagc tttagctgat gctaaaaact atgttgaaac aaattataca 1344541 aatcaaaagt taactgttct aacaggatca aatgcaatcc aagatgcgag aataagcgga 1344601 aatgattaca aatacggaat cacttttatg gacatagggg ccaataacac tacaggatac 1344661 ccgctcactt atggatttgt aaaaaatgaa aagcatagta attatcgctt tactcagtat 1344721 ttctatggaa atgcagacac aactagtgga agttatgatc atgtagggac ttggatccgc 1344781 cattggtggg cagattcagg ctggactgcg tggcaaaaga tatcagggtt tgctcacgct 1344841 aatattggga ctactgggcg tcaagccctt attaaaggag aaaataacaa aattaaatat 1344901 aaccgtatta taaaagatag ccataaattg tttgatacaa aaaacaatag gtttgtagcc 1344961 agtcatgcag gaatgcattt agtcagtgct agtttatata tagaaaatac tgagcgatac 1345021 tccaattttg aattatatgt ttatgtaaac ggcacaaagt ataaattaat gaatcaattt 1345081 agaatgccta ccccttccaa taacagtgat aatgagttta atgcaactgt tactggatct 1345141 gttacagttc cgcttgatgc aggagattat gttgaaattt atgtttatgt tggttattcc 1345201 ggggatgtaa cacgatatgt tacagattcg aatggagctc tcaattattt tgatgttctg 1345261 gagcttggcg gaagaaatta cccgagagtt taggaggtac ctttatgatc ttatatgatg 1345321 ccattatgta caagtatcca aacgcagtat cgagaaagga ttttgaattg cgtaatgacg 1345381 ggaacggttc atacattgag aaatggaatc tccgggcgcc gttgccgact caggcagaac 1345441 tcgaaacctg gtgggaagag ctgcaaaaaa atccgccgta cgagccgcct gatcaggtgg 1345501 agcttctcgc tcaagaattg tcacaggaaa agctggcacg caagcagctt gaagagctga 1345561 acaaaacatt agggaacgag ttgtcagata taaagctatc attactttcc ttgaaaggag 1345621 attatgctga atgaattatt gggtgcttgc cctctattat gagtgggcga caacggatat 1345681 ggtgaaacag gctttagcat atgaagactg ttcaattcag gatctggcag agggtgtgaa 1345741 caaaaagctg atcacagctg accagtataa agaaattacc ggtaaagcca tgtaaggctt 1345801 ttttattttg cctgttttta gatcaaagga ggatgaagat ggtgaagtat caatatgaat 1345861 ttcctctcga taaggctgga aaagccggcg ctgtaaagcc ctatcgagga ggaaaaaatg 1345921 attttgtgac acctgtttcg aatttgtcag gcgtagcgga gattttaaca aatgctgctt 1345981 taaaggcgac tgaggcatac agtcagctcg ggcaggacag gcttggcgca gttctgattt 1346041 cgaaagtgaa gggctgggcg tatgcagatc gtgaaggtac gctctttata gaagaaagcg 1346101 acaacaacaa tgtttggaca acgacagcag cagttaatgt cgcagcaggc gtcctgacag 1346161 cgacggactg ggtatatctt tctaaacgct attaccgttt ccgctatgtg aacgggaatc 1346221 ttcagcaatc tgagtttgta ttataccaat cagtcggtgc gggtgagatg gatgtgcgtg 1346281 tcaatgaaaa aacgccttta cagattgact ttgcggagaa tcaaacacac gatggacggc 1346341 tgaaagtcga ggctcgcaaa acatttgact ttgtctttca tgaaaatgca gagtccgcca 1346401 gcgagggggc tgctttacct gttgacggtg ccgcgcattt actcgttgaa gtctacggca 1346461 cagcagaaat gagcgaagtc aaattttggg gcaaatcggt gtcaggacag aaactgccga 1346521 tcagaggcgt gaaaactgat gatgctacca ctgcctccag tacattagga aaagctgagg 1346581 catgggcctt tgatattaaa gggtttaagg agatcatcat ggagattatc agtatcaccg 1346641 gcggtactct ttcggtaaaa gggaccgcgg tttcataata gtctcggccc tcggaaggga 1346701 ggtgatctgc atgtgaagga ggagtgagag atgcagcaag aggcagacgt gaatgtgttt 1346761 cagcaggatt tagcagacat gaaaggcgag cacaaagcac ttgagcagag ggtttccgca 1346821 ttagaacgcg tgtctgaccg gcaagaccag caaatcatga cgctgaacga aaaattaaac 1346881 aaaattgaag aaaacaccac gtggattaaa cgcaccatca caggtgccat cattacagca 1346941 gtgtctacag gcatcattgg cggagccatc gccattatgt acagcctgct gcagcattaa 1347001 agggggattt ttatgaacac gtttgacaag ggcacggtca tcaggacggt gcttctttta 1347061 attgctttaa tcaaccagac catgctgatg ctcggcaaat caccattgga cattcaggag 1347121 gagcaggtca atcagctcgc tgacgctctt tattcagccg gttccatcgc atttacaatt 1347181 ggaacgacac ttgccgcttg gtttaaaaac aactatgtaa cagaaaaagg gaaaaaacag 1347241 cgcgacttgt taagggacaa taatctgacg aaataaggag agatgaaaat ggttaacatt 1347301 attcaagact ttattccggt tggcgcaaat aaccgtccag gctacgcaat gacgccgctt 1347361 tacattacgg tgcacaacac agcgaatacc gcagtaggag cagatgctgc agcgcatgcc 1347421 cgctatttga aaaatcctga tacgacgaca agctggcatt ttacagttga tgatacagaa 1347481 atttatcagc atctgccttt aaatgaaaac ggctggcatg cgggagacgg aaatggcagc 1347541 ggcaaccggg cttctattgg aattgaaatt tgcgaaaatg ccgatggcga ttttgcaaaa 1347601 gcaacagcaa atgcccagtg gctcatcaaa acattaatgg ctgaacataa tatcagtctc 1347661 gccaatgtcg tccctcataa gtattggtca gggaaggaat gtccgcgaaa attgttagat 1347721 acgtgggatt cgttcaaagc aggaattggg ggaggcggca gccaaactta cgtcgtgaaa 1347781 cagggcgaca cacttacatc tatagcgaga gcatttggtg ttacggttgc tcagctgcaa 1347841 gagtggaaca atatcgaaga cccgaatctt attcgcgttg gtcaagtatt aattgtaagt 1347901 gctccatcgg ctgctgaaaa acccgagctc tatccgctcc ctgatggtat cattcaattg 1347961 acaacacctt atacatcagg agaacacgtc tttcaggtgc aacgagcact tgcggctctg 1348021 tatttttacc ctgataaagg cgctgttaac aacggaattg acggcgttta cggaccgaaa 1348081 acagctgacg cagttgcccg ttttcagtct gttaacggtc taactgctga cggtatctac 1348141 gggcctgcga cgaaagagaa gatcgcagcg caattaagct gatcaaagac cataaaaatc 1348201 ccggagccgc tccgggattt attttttctt cttcaacttt tttataattc cagcactgcg 1348261 ctccctcacc cgaagcgagt acccggaaag cccaaacctt ccgtaatcaa caaacttcac 1348321 acgcctcacc aattttttca ctgtatcacc tgacattatc ctctgtttgt atttattata 1348381 tgtcaccctt taagaaaagg aataaggaca agagctgttt tcccttgtcc ttttagtgtg 1348441 atcatgcttt ttttcgttta tactcgtcaa tcagccgttc gttttctttg aagattcttg 1348501 ctgtatgcgg actgacttga tagcttgcga cactggtggt tgaacgtttt ttcaggattt 1348561 taaacggctt cgccgctctg ggctcgcatc tgttttgaaa cgcacgttcc attatccttc 1348621 accttcctcc tcaattggca gcaccaaatc atatatgctc gttaatgacg taaatagcaa 1348681 ataatcaaat tccgtgacaa tgctgtcaga cgtcagcttg atgacatagt tctgtgtctc 1348741 gatggtaaaa gggatgagaa ccacttttcc gtattggtcg taataaacat cctttcgatc 1348801 gagccgtgtt tgtacatctg ccggatcatc catatgctcg gttaaccggt ctttatcagc 1348861 ctgtgtcgaa tagtggcaaa gagaagccgt taagttcatt ttatcagcat aggttttcag 1348921 cagcttatca ataccttcag cataagcatc tatacttcca taataaacat ggatcggttc 1348981 gtttttcaat aggtattggt atgttttcag ccgattgaga tacatgtgga gcatttcgtt 1349041 gttttcttca agaatttctc ttgtgtctgt ttcaagctcg ctgccggcca gttttttgac 1349101 atatgcactt aagaagataa aagcatcaat caaagcaaaa ctgactgcga caatgagata 1349161 ccgttcccag tgggtaaata gggaagtggg ctcatatgtc cagtatacca tagcgcccag 1349221 aacaaacagc aaataccaag ttttccgaat ggcggacatt ttttctttga ccttcgcttc 1349281 gaaacgccac gtggcataca cgtataaccc cagtccggcc acgatgcacc agaccatgat 1349341 ctgaaagaat aaaaccatat tcgaatccct cacatctgaa ataggttctg cttattgtat 1349401 tcgagagatc cggatggttt tcctgttcca tcaaaaaaac cgctcctttg acagaagcgg 1349461 tgtgacatta aaatatcata tttaaaataa agtaggcgat ggcaccaagt gtcgctgaaa 1349521 tcggaagcgt gatgacccat gtaatgagca ttcgcttggc cgtaccccag tttacgcctt 1349581 ttacgcggtg ggacgcaccg acgccaagaa ttgatgaaga aatgacgtgg gttgtactga 1349641 ccggcaaatg aataaacgtg gcgccgaaaa taatggctgc tccggttaag tcagcggaaa 1349701 caccgtttac cggacggatt ttcatgatct ttccgccaac ggttttgatg attttccagc 1349761 cgccgattga tgttccgaga cccatggctg tcgcgcaggc gaattgcacc caggtaggaa 1349821 tatcattagc agaagtatgt aaattcgctg tgatgagagc cattgtgata attcccattg 1349881 ctttttgcgc atcgtttgtt ccgtgtgtat acgattgcag ggcagctgtt acaatctgca 1349941 ctctgcggaa ttgcttattc gttttcgcca agttgctgtc tttgaaaatc agcttaacga 1350001 tgctataaag aataaaacca aggacaaagg caataattgg tgatagaatc agtgcttcaa 1350061 tgattttaat gaagccctta tagtttaacg ctgcaaatcc ggctgccgca atggctgcac 1350121 cggcaatagc gccgatgatg gcatgggatg agctgcttgg gataccgtag taccatgtga 1350181 taaggttcca ggcaattgca gcgagtagcg cagccaaaat gacaacagag ccattttcca 1350241 gcgtataagg atctacgatg tctttcgtaa tggttttggc aacacctgta aacgtcattg 1350301 ctccgacaaa gttcatcaca gcagccaata taatggcatg gcgcggtttt aacgcttttg 1350361 ttgataccga agtcgcaatt gcgtttgccg tatcatgaaa cccgttgatg aaatcaaacg 1350421 ccagagcaca aatgactatt agtatcgtta atattaatag aatatccatt tttacccctc 1350481 gttacgcgtt tttcataatg atggtttcaa gattattggc aacactttga caagagtcgg 1350541 cgatttcttc aagcgtttcg tatatttcac gatattgaat gactttgatt ggatctgttt 1350601 catttccgaa aagattcttt aatgattttc tgtgcaagtt gtcacaactg tgctcatact 1350661 ctttaatttt gattgcgtga ggctgaatat cctttaagcg attttctgcc agcagctcga 1350721 tcgtaatcaa aatctctttc gcacattctc tgatatatcc gctgaattta tcaatatgct 1350781 cgtctgatga agtaattgag aaaatctcca tcatggcaga gaaatgttcg attccgtcaa 1350841 gcacatcatc caagctgttt gtcagctgaa ggatatcttc gcgctcaata ggagtgatga 1350901 acgctttgtt aagctcttta atcatgacat gaacatgatt gtcacctttt gtttcatatt 1350961 cctttaacgt atctgcaaat tctttaagag tcgtttggtt agtgacctta aaattcacaa 1351021 aatattctgc agtttcgtct atgttctttg caatttctgt taaaaggagt gagaacttat 1351081 ctttttttct tcttatcatt aaaaaccctc catagtttga atgaacaatg cacacatcaa 1351141 attattatat agccttttgt cgaaaaaaaa caggtaaagt cgaaaaaaac gtatcttgac 1351201 ttttttgata aatcgtgtct ccttattttg acctacttcg ctttaaaaaa acgacccaag 1351261 tttgcaaaaa ctttctgctt aacgtaaaaa gtatatcaaa agttgtgttt ttcctgtcaa 1351321 cttttatctt ctgtttcacc aaaaaacggt tccctaaaca agggaaccgt tttatcagct 1351381 tgcttttcgt tttttcatcc cgtaataaac aggcagtccg gcaaggccga tgaggatgga 1351441 taatccgcag ctcattgtat ctgtaatgag tgtgctgcct aacacaaaga aggagcccgc 1351501 gattgccaga attggcataa atggataaag cggaacactg taggcgcgct tttctccctt 1351561 tgctcgcttg cggagaataa acactgcaaa aaaggccatc acataaaaaa tgtagatcat 1351621 gaaaatggag atttctgaga gcttatcagg gttgctgatc agcatcataa tcaaagccaa 1351681 agcaatttga aaagaaatcg caatccatgg tgtgcggaac gacgggtgta catgtgacag 1351741 tttttcagca aatggaagct gtttgcgttc cgccattgca aatgaaacac gcgggaaaga 1351801 aagcaccttt ccatttaagc acccaaagat gctgacgata atccctacac tgatcagctt 1351861 tccgccaatt gaaccgaaca gcatggttgc agcggtgctt gtcgcatttt caccaagcgt 1351921 gacaatttcg ttcgctgaca ggatgtgaag caatgcaaaa ttaatgaaaa tatagatcgc 1351981 cgttacaatt aataatccgc ccgtcatagc gcgtggcagc agcttttcgg gatttttcat 1352041 ttctccgccg agagcggcaa ggagaatcca tccgtcataa gcaaacaacg tagctaaaat 1352101 agccgccccg aagttcatat cagaaatgct ttcgtttact gctgtgaaga tgtgctgatc 1352161 gcctttccaa aggccaaaga cgatgatgca ggcaatcgga atcagttttc cgatcgttgt 1352221 cagcgtttgg acaaaaccgc cgtattttgt accgataata ttaatgacgc ataaaaagag 1352281 aactgctata attccaatga cttttgatag tccagatccc cagccgaaaa gattcgccat 1352341 taaagatcca aaatataaac ccagcgcgcc aataatcgcc gggccgtaaa tgataatctg 1352401 cacccagccg cacaaaaatc cccaaaactc gccgtacact tcttcaaggt acgtataaag 1352461 cccgccggtt tttggaatct gcgttccgat ttccgcgatt gtcaaaccgc ccgccagtgt 1352521 taaaataccg cctaacagcc aggcgaaaag cgccattttt gaatcacctg aataagcaag 1352581 cacagcgccg ggcttcataa aaacaccaga accgataatg gttccgatga caagagtaag 1352641 ggcaaacaag aggcctatct cttttttcaa accgttgtct tcagtatgca tgtccttaac 1352701 ctcctatgat gttgaagctt catgttgaag aatctatttt ttcatattgt aaaccctatt 1352761 ttagaaaagt gaaataaaat aaattttctg attttcgaaa tttgctttgt gtacagcaga 1352821 taaaactgta gaaatacctg ttttaatggt ctataaacga ataaaattca taatttttat 1352881 ttacaaagtt cgtgttttat gtattaggat tttagccggt acagagggga gatgagaatt 1352941 cagaaaatga acgaaccttc ggtgaagctg atatgttgac tttctcatgc gaataaaata 1353001 ctttgttatt agaacaataa atatacaatt atgatatgat atctcgaaat cgagataaaa 1353061 taacctggag ggacagcata tgaaagttaa cggcattcac cacgtatcgg cattaacggc 1353121 cgacgcacaa aaaaacttgg atttctataa gaaagtatta ggattaaagc tcgtcaaaaa 1353181 atccgtcaat caggatgaac cgacaatgta ccatctgttc tacggagatg aagtggcaaa 1353241 cccgggaact gagctgacgt ttttcgagat tccccgcatt gcaccgtttc atgcgggaac 1353301 aaacagtatt tcttctattg gattgcgcgt tccaggcaca gaagccctgc attactggaa 1353361 agaacgtttt gaagagcagc aagtaacgca cagcggcatc tccaaaagag ccggacgtga 1353421 catattggca tttcaagatc atgaggggca gcgacttgtg ctgactgctg atgaggaagg 1353481 aaaaggatat ggcctgcctg ttaaacagag cggcattccg gaagaatttt cgtttcgcgg 1353541 gttagggccg gttgaactga ctgtgccata tgctgaacca actttacacg tattgacgaa 1353601 tattcttgga tttacagaaa tcagccgtga accagtcgaa gggcaaggaa ccgccgttat 1353661 tctggaatca ggagaaggcg gtgctgcaac ggaaatccat ttaatagaaa gaaacgatct 1353721 tccgcgagag cgtcaaggca aagggagtgt tcaccacgtc gcatttcggg taagagatga 1353781 agaagaactt gccgggtggc accggatcat cagccgcgaa ggctttagca attcaggcat 1353841 agttgagcgc tactatttca aggcgctgta tttcagagaa ccgaacggca ttttgttcga 1353901 gttatcaaca gacggaccgg gctttatggt agatgaaaat cttgatgagc ttggccaaac 1353961 gattgctctt ccgccatatc tagagcatcg aagagcagaa attgaagcaa aattgaaacc 1354021 gatccaataa attgtgattc ttttgccttc cggcgccgcc ggagggcttt ttttattacc 1354081 ataattaatt ttgacctaaa cagcatgcct tattagggag gaaatatcag atgctgattg 1354141 ggagaaatgg cttaaaaccc tttgcaaata tgggtgattg gtatggaatg gcctcggcaa 1354201 aaatattgtc tttgtttatt aatagtttat tcatatttgc ttgttacact atttcaaagt 1354261 tagacaaaaa ggagtgaaaa ataagtggaa aagaaaaaac gcgagctgga tatcgtcctc 1354321 ctcctcattt tgctcgcatc tgcattctta aatatctata acatttggaa ggacgacacg 1354381 gtgaatcctt attacaccgc ggcagttaca agtatgatgc aaagctttca taatttcttt 1354441 tatgcttcgt tcgatgctgc cggctttata acagtagata aaccgcctgt tacataccaa 1354501 atccaaacga tcagcgcact gatattcggt atgcacggct ggagcgtcat cctgcctcag 1354561 gcacttgctg gtgtaggttc tgtccttctt atgtacttgc tgataaagcc gacatttgga 1354621 aaaacggcgg cgcgtattgc ctcatttgtt atggcatgta cgccgatagc tgtagctgta 1354681 gcacgtacaa acaatgttga tgcattactg gtatttttct tattgcttgc tacatggctt 1354741 ctctttaaag cgatcagaaa aggaaagctg atctggctgt tagcagcatt tttcgttgtt 1354801 ggagtaggtt ttaatacaaa aatgctgcag gcttacatga ttttaccggc tttcttattg 1354861 ttctatctga ttgcggcaaa cgccacaatc aagaaaaaaa tcgtttcatt ggtaagtgcg 1354921 ttagccgtat tagcagccgt ttcgttatcg tggccgctca ttgttgacaa tatccctgca 1354981 agcaagcggc cttatatcgg aagcagccaa accaactctg ttttggaatt ggctttcggc 1355041 tataacggaa tccagcggct gacaggccaa aattcaggcg gcggccaggg tgcgccaaac 1355101 aaagacgctt caaaagaaat gtcttcttct gataacactc aagcaccgcc taatcagtca 1355161 tcaagcaaca gctcatcaag cgatggtaaa tcctcaaatg gcaatatggc ggcgcctcca 1355221 tccaatggcc aaatgccaag cggcggtcaa ggaggccctc caagcggcgg agatggcggc 1355281 caaggcggac ccggcggaga cggagggaaa ggcggtacag gaaccggttc gaaaatgcaa 1355341 tcaggttcag ggatgtttgg aacgggaaca cctggtccac tgcggctttt ccaacaagag 1355401 ttatctgatc aaatcagctg gcttctgcca tttgcgatat ttggaatcgc aggcttactg 1355461 atcgctggcg caagagaaag aagaagatta tctgtagagc agaaggaaac ggtgttctgg 1355521 gttgcgtggc ttgtaccgat tgccggattc ttcagtgtcg cagaattttt ccatcattat 1355581 tatctcatca tgctggcacc gccgattgcg gctcttgtcg gtgcggggtg ggtcgctctt 1355641 gttcatctgt accgcaatca gacaggctgg aaagcatggc ttttgccggg agcaattatt 1355701 gcgacaactg gatttgaatt gtttattctc agaaactaca acgatcaaat cggtgttgga 1355761 tggagtatcg gggtaggtgt tatcggcgtg ttgtcagcga ttgctttgct gctgtttaaa 1355821 cagcgccaaa aaccgttcag ttattatgtt tcacttgcag ctctcctcgc attgctggtg 1355881 atgccgatgt attgggcaag tacaccgctt ctgtacggag gcaacagctc actgcctgaa 1355941 acaggccctc aactcgcatc aatgagcgga aaaggcatgg gaatgtctga tgcgactgta 1356001 aatgaaaaac tgatcaaata tctagaggag aataactccg gagctgaata cctattcgcc 1356061 acaaccgatt cgaacacagc ggcaccatat atcattaaaa cgaaaaaagc tgtcatggct 1356121 attggtggat acagcggttc tgacccggca atcacactga ctcaattcaa aaaacttgta 1356181 aaagaaggaa aagtgaaata cttcttggct tctggaatgg gaagaggcgg aaacaatgac 1356241 attgttgaat gggttgagaa aaatggaaaa gaagtagcat cagaaaaatg gcaatcaagt 1356301 tctgatcaaa aaacagaaaa tactgattca gctgatacat caagcagcaa ggcttcaggt 1356361 gaaaacggca aaatgggcgg acctggcgga atgaatcagt cagcaacatt atacgaacta 1356421 catgctgatg aataggaggc aaaaacatga gcagacatat tcaatattca attgttgtac 1356481 ctgtgtataa tgaagagctt gtcattcatg aaacctatca gcgcttaaaa gaggtcatgg 1356541 atcaaacgaa ggaaaactac gagctgcttt ttgtcaacga tggcagcaaa gaccgcagta 1356601 ttgagatttt aagagagcac agcctgatcg atccgagagt gaaaattatt gatttttcaa 1356661 ggaattttgg acatcagatc gccattacgg caggtatgga ttatgcacag gggaatgcaa 1356721 tcgtcgtcat tgacgccgat ttgcaggacc ctcctgaact gattttagaa atgattgaaa 1356781 agtggaagga aggctatgaa gtcgtgtacg ccgtacggac taaacgaaaa ggggaaacct 1356841 ttttcaaaaa acaaaccgcg gctatgtttt accggcttct cagcggtatg acagatattg 1356901 atatcccgat tgatacgggg gattttcgcc tcatggacag aaaagtctgt gatgaaatga 1356961 agagattaaa agaaaaaaat ccatttgtaa gagggctagt cagctgggtg ggtttcaaac 1357021 agacagcggt cgagtatgta cgtgatgaaa ggctcgccgg agaaacaaag tacccgctca 1357081 agaaaatgct gaagctgtca atggacggca tcacgacatt ttcacataaa ccgctgaagc 1357141 tggcaagcta tgcggggatt ttaatgtcag gtactggatt tctgtatatg tttatcgtgc 1357201 tgtatctgaa gctattcaca gacagcacga ttaccggctg gtcatcactt attgtgatcc 1357261 agctcctgtt cagcggcatt gtccttctga ttttgggcgt gattggcgaa tatatcggca 1357321 gaatctacga tgaagccaaa gacaggccgc tttacatcgt ccaaaaatcg tatggaattg 1357381 aaaataaaag actctataga gaccagcata tgtcataacc tcaaaccccc tgtccgtaat 1357441 ggacaggggg tttttatgct ctgagcacga tctaaagcaa aagatgctga tagatatatg 1357501 gaaattgggt aaagaagaga ttgtgagctt gtactgcggt tcagtcatgc tgaaataaaa 1357561 acagcaaaac ttaaagattt cgtcctcggc tttgctgcat gtcagctgtt atattggggg 1357621 gcttttaaga aacgcatgat tagagccgta ccagttatgt ttaatagaat actcgtaccc 1357681 aatacaattc cccacgtcaa cgtcgattca gagagaagaa agctcagcaa aagaaaagcc 1357741 aatcctgcgc agatcatacc cagtcccacg gttttcatgt tcatgcctcc tagcaaacga 1357801 tgtttctagc atctgatgtg aatgatgtca atctgtatga tatacggata tctcgtcaga 1357861 aagtttcata gaacaattag gtcttttatc taataaaaag cctcagaccg cttttacggc 1357921 ctgaggcatt atgtcttacg aagttttctc ttctttttga tccagtttaa tttttttcgt 1357981 catttctttg ccgtttcgga gaattttcac ttcaacggta tcaccgatct ttgcgtcttt 1358041 atataagata ttgcgcaatt cactgcctgt atcaatttct ttacctttta ggccgatgat 1358101 aatatcctcc gcttttaatc cggccttttc agcaggagag cctgaagcga cctcacggat 1358161 gtaaacgcct ttattcagct ggctgccgaa caggccgagt gtgccttctt ggtaattttg 1358221 cggcacttgc tctagatcaa gcatgctgac accgatatat ggacgttcaa tttgtccttt 1358281 agacagcaat tcttcagcaa tcggttttac gtcattgctt ggaatggcga atccgatacc 1358341 ctcaacatca tcctcactga ttttcatact gttaatgccg acaattttgc cgtctgtatt 1358401 taacaaagga ccgccgctgt tacctggatt aattgctgcg tctgtctgaa tgacgttaat 1358461 gctcgtttcg ccggctgatg tagacattga aaccgttctg tccacgccgc ttacaattcc 1358521 ttgtgttact gtgcgggaca ggtcttttcc aagcggatcc ccaatcgcaa taacggtctc 1358581 gcctgttcta agatcagatg aatcaccgaa gtttgccact tttgtgacgt ggtcatcact 1358641 gatttggagg acggctaaat cagttaacga gtcactgcct accagctttg cagtaacctc 1358701 agtgccgtca tataaagata ccttcagtga tgatgcccct tctacgacgt ggttatttgt 1358761 aatgatataa gccttgccat tctctttttt gaaaatgaca cctgaccctg aaccgctttc 1358821 tgtatcttcg ctggaatcag aagaactaga gccgaacaaa gagctgtttg attgtgcctg 1358881 aagatttgta ataccgacaa tcgctggtga aaggtcttct accatatctg agattttaga 1358941 agagtcctcg ctcttgaatg cagatgagct gcttgagctt tttttagatt cagaggaggt 1359001 gcttgttgct gtaacagatt gcgtttgctg ctggctggat gattgttttg cagtgtcctg 1359061 agaatcatgg tcaccaagcg gtgtaaacgt gtaaatgcca agagcaagac tgccgccgat 1359121 cactccgcca agcaacggtc tgaaccatcc gaatcctcgt tttttcttct cctgatcatg 1359181 aatgacattg cgggccgagt aggaggcgct ctgatcgttc tctttcgtta aaaagacctc 1359241 attctcatta cctttcgttc tgttttcatc acgatagtta tccatcatgt tcactccgtt 1359301 tctctatttt cacatgtcta tttatattga taggtttatg acttgagttt atcataaaca 1359361 aaaactgtgg gataaaaatg aaaagattat gggaaattgt gaaaaagtgc ggaaaacggt 1359421 acacttcata ttgtatatga aaggactgag tcgatggaac agattggatt gattggatat 1359481 ggcagcatgg cggatatgat cgctagacag ctgttgaaac atgaacaaat aaaagagaat 1359541 gagctattta ttgagacgag aacgaagggg gagcggctgc gggcactcat gtcagattat 1359601 ccaaacgtat cggctgatcc gttggagaat tgggcaaata cgtgccaatt gattttgata 1359661 tgcgtcccgc cactccatgt catcgaaaca atgcgccgtc tgtacccgta tgtgaacaga 1359721 aatactcaca tcgtatccat agctgccggt gtgccgctgc gtcttttgga ggcagaaaca 1359781 gaagccggta tctcacgtgt tattcctgcc attacgtccg aagcagaagc cggcatctca 1359841 cttgtcgttc acagtgaagc actggctgca gagaaaaaag aacgtctgaa tgaattgtta 1359901 tcggttttca gccgtgtacg ggaaatcaaa gaatcgaatt tagatgtggc cagcaattta 1359961 acgagctcgg caccgggatt catagctgca atctttgaag aactggcact gtctgccgtc 1360021 agaaacagca gcctgtccaa agaagaagcc tttgattttc tgattcattc gctatacgga 1360081 actggcaaga tgctgatcga aaaaaatatg tctttcgagg agacgctgga acgtgttgca 1360141 accaaaggcg gaataacggg agagggagct gaggtgatac acgcctctgt gccggacgtt 1360201 tttgatgagg tatttgaaag aaccctgaga aaatatgaac tgcttacaga acaggttggt 1360261 aaacaaacat gaatccttga aagaggattc tttttttatc actgaatgat tgagattttt 1360321 cccagttata ttgcattttt cctctttttt taatataatt tgttagaata ttcataattt 1360381 agtaaaaaag gaggagcgtt atgaaattgt acatgtcagt agatatggaa ggtatttcgg 1360441 gtcttccgga cgataccttt gtggattccg gcaagcggaa ttatgaacgc ggacggctta 1360501 tcatgactga agaagcaaac tactgtattg ctgaagcgtt taacagcggg tgtaccgagg 1360561 tgctggtcaa tgacagtcat tcgaagatga ataatctgat ggttgaaaag cttcaccctg 1360621 aagcagactt gatttctggt gacgtcaaac cattttcaat ggtggaggga ctggatgata 1360681 cgtttagagg cgctttgttt ctcggttatc atgcgagagc ctcgactcct ggtgtcatgt 1360741 cacacagcat gattttcggc gtccgtcatt tttacataaa cgatcggcct gtcggtgagc 1360801 ttggattaaa tgcatacgtt gccggttatt atgatgtccc ggtattaatg gtagccgggg 1360861 atgaccgggc ggcgaaggaa gcagaagagc ttatcccgaa cgtgacgaca gccgcagtca 1360921 aacaaaccat ttcaagatcc gcagtgaagt gcttgtcgcc tgcgaaagcc ggacggctgt 1360981 tgacagaaaa aaccgcattt gccctgcaaa acaaggacaa agtcaagccg ctcacaccgc 1361041 ctgacaggcc agttctgagc attgaattcg ccaattatgg ccaagcagaa tgggcgaatc 1361101 tgatgccggg aacggaaatc aagacgggaa ctacaaccgt tcaatttcag gcgaaggaca 1361161 tgcttgaagc ctatcaggcg atgcttgtca tgactgagct tgcgatgcgg acatcattct 1361221 gctaaagggg tgttttaggc tttggcgcga tacatgataa agcgtttttg ggcaatggca 1361281 gctacgattt tggtgattac caccctgact tttgttctca tgaaggtcat tcccggatct 1361341 ccttttaacg aggagagagg cacaaatgaa gccgttcaaa aaaatctcga agcctactat 1361401 cacttagacg atcctctcat tttccaatac attttctact taaaatccat cattacattc 1361461 gatttcggac cttcaattaa aaaaccgtcg gacagcgtaa atgatatgct ggaacgcgga 1361521 tttcccgttt cctttgagct tgggatgaca gcgattgtca ttgctgtgat ttctgggctg 1361581 gtgctgggcg taatcgctgc actccgccgc aatggctttt tggactacgc cgcgatgagt 1361641 cttgcagtac tcggcatctc catcccgaat tttattctgg caacattgct cattcagcaa 1361701 tttgctgtca atctcaaact atttcccgct gcgacatgga cgagcccgat tcatatggtg 1361761 cttccgaccg cagcgcttgc tgtagggcca atggcgatca ttgccaggct gacacggtcg 1361821 agcatggtcg aagttctgac acaggattat atccgcacag caaaagcaaa agggctttct 1361881 ccgttcaaaa ttatcgtaaa acacgcactc agaaatgcac tcatgcccgt cattaccgtc 1361941 ctgggcacac tcgtcgccag catcttaaca ggaagctttg tcattgaaaa aatctttgcc 1362001 attccgggaa tgggaaaata ttttgttgaa agcattaatc agcgggacta ccccgtgatt 1362061 atgggaacga ccgtttttta cagcgtcatt ctgattatca tgctgttttt ggtcgatttg 1362121 gcctacggtc tcttagaccc gcgcattaaa ctgcataaga aagggtgaag cgtgtgaatc 1362181 tccctgtaca aacggatgaa cgccagccag aacagcacaa tcaggtgcct gatgagtggt 1362241 ttgtcttgaa tcaggaaaaa aatcgggaag ccgattcggt caagcggccg agtttgtcat 1362301 acacgcagga tgcctggagg aggctgaaaa aaaataaatt agcgatggcc ggactcttta 1362361 ttcttttatt tctttttgtc atggcagtta tcgggccctt tttatcgccc catagtgtcg 1362421 tacgccaatc gctgacagaa caaaatcttc cgccctcagc cgatcattgg ttcggcaccg 1362481 atgaactcgg ccgggatgtg tttacccgaa catggtatgg cgcgagaatc tcgttgtttg 1362541 tcggcgtgat ggcagcactg attgattttt tgatcggtgt catttacgga ggcgttgccg 1362601 gctataaagg cggcaggatt gacagcatta tgatgcggat tatcgaagtg ctgtacggac 1362661 tgccgtatct gcttgttgtc attttgctga tggtgctcat gggaccggga ctgggcacga 1362721 ttattgtggc gctgactgtg accgggtggg tcggcatggc gagaattgta agaggccagg 1362781 tgcttcagat taaaaattat gaatatgtac tcgcctcgaa aacctttggc gcgaaaacct 1362841 ttcgcatcat ccggaagaat ttgctgccga atactatggg agcgatcatc gtacaaatga 1362901 cattaaccgt acctgccgcc atattcgcag aatcattttt aagctttctc ggcctgggca 1362961 tacaggctcc gtttgcaagt tggggcgtga tggcgaatga cggcctgcct acgattttat 1363021 ctgggcattg gtggcgcctg ttttttccgg cctttttcat atctctgacg atgtacgcgt 1363081 ttaatgtgct gggggacgga ttgcaggatg cgcttgaccc taagctgagg aggtagctgt 1363141 atggaaaaag ttctgtcagt ccaaaatctg cacgtgtctt ttacgactta cggcgggacg 1363201 gttcaggcgg tcagaggggt gagctttgat ttgtataaag gagaaacctt tgcgatcgtc 1363261 ggcgaatccg gctgcggcaa aagcgttacc tcccaaagca tcatgggcct gcttccgcct 1363321 tattcggcga aggtgacaga cggcaggatt ctatttaaaa acaaagacct ttgccgtctc 1363381 tctgacaaag aaatgagagg tataagggga gccgacattt ctatgatttt tcaagacccg 1363441 atgacggcgt taaaccctac gctgactgtc ggcgaccagc tgggggaagc gctattgcgc 1363501 cacaaaaaaa tgagcaaaaa agcggcacgg aaagaggtgc tttccatgct gtcattggtt 1363561 ggtattccag atcccggaga gcgcctaaag caatatcccc accaattcag cggcggtatg 1363621 agacagcgga ttgtcattgc gatggcgctg atttgcgagc ctgatatctt aattgcggat 1363681 gaaccgacca ccgccctgga tgtaaccatt caggcacaga ttttagagct gtttaaagag 1363741 attcagagaa aaacggatgt gtctgtcatt ctgattacgc acgatttagg ggttgttgcc 1363801 caggtagctg acagagtcgc agtcatgtat gccgggaaaa tggcggaaat cggcacaaga 1363861 aaagatattt tttatcagcc gcagcaccca tatacaaaag gcctgctggg ctctgtcccg 1363921 cggctggatt taaatggcgc tgagctgacc ccgattgacg gaacgccgcc ggatttattt 1363981 tcgcctccgc cgggctgccc gtttgccgcc cgctgtccga acaggatggt tgtgtgtgac 1364041 agggtgtacc cgggccagac gatcagatct gactcgcaca ccgtcaactg ctggctgcag 1364101 gatcaacgag cagagcatgc ggtgctgtca ggagatgcga aggattgaac atgaaaaggg 1364161 ggaagaggat gaaacgagtg aaaaagctat ggggcatggg tcttgcatta ggactttcgt 1364221 ttgcgctgat ggggtgcaca gcaaatgaac aggccggaaa agaaggcagt catgataagg 1364281 caaaaaccag cggagaaaag gtgctgtatg taaataatga aaatgaaccg acttcattcg 1364341 atccgccgat cggctttaat aatgtgtcat ggcagccgtt aaataacatc atggaggggc 1364401 tgacgcgtct tggcaaagat catgagcccg agccggcaat ggcggagaaa tggtctgttt 1364461 cgaaagataa taaaacttac acatttacga ttcgggaaaa tgcgaaatgg acaaacggag 1364521 atcctgtaac agccggagac ttcgaatacg cgtggaagcg gatgcttgat ccgaaaaaag 1364581 gcgcttcatc ggcattccta ggttatttta ttgaaggcgg cgaagcatat aacagcggga 1364641 aagggaaaaa agacgatgtg aaggtgacgg caaaggatga tcgaaccctt gaagttacac 1364701 tggaagcacc gcaaaaatat ttcctgagcg ttgtgtccaa tcccgcgtat ttcccggtaa 1364761 atgaaaaggt cgataaagac aatccaaagt ggtttgctga gtcggataca tttgtcggaa 1364821 acggcccgtt taagctgacg gaatggaagc atgatgacag catcacaatg gagaaaagcg 1364881 acacgtattg ggataaggat acagtgaagc ttgataaggt gaaatgggcg atggtcagtg 1364941 acagaaatac agattaccag atgtttcaat caggggaact tgataccgct tatgtccctg 1365001 ctgagctgag tgatcagctg cttgatcagg ataacgtcaa tattgttgac caggcgggtc 1365061 tctatttcta tcgatttaat gtcaacatgg agccgttcca aaatgaaaac atcagaaaag 1365121 cctttgcgat ggctgtggat caagaggaaa ttgtaaagta cgtcacgaaa aataatgaaa 1365181 aaccggcgca cgcctttgta tcgcctgggt ttacgcagcc tgacggcaaa gatttccgtg 1365241 aagcaggcgg agacctgatc aagcctaacg aaagcaaagc gaagcagctg ctcgaaaagg 1365301 gcatgaagga agaaaactat aataagcttc ctgcgatcac gcttacttac agcacaaagc 1365361 cggagcataa aaagattgcc gaagctattc agcaaaaatt gaaaaatagc cttggagtcg 1365421 atgtgaagct ggccaatatg gaatggaacg tatttttaga ggatcaaaaa gcgctgaaat 1365481 tccaattctc tcaaagctca tttttgcctg attatgcaga ccctatcagt tttctggaag 1365541 cctttcaaac gggaaattcg atgaaccgca caggctgggc caataaagaa tacgatcagc 1365601 tgatcaaaca ggcgaaaaac gaagccgatg aaaaaacacg gttctctctt atgcatcaag 1365661 ctgaagagct gctcatcaat gaagcgccga tcattccggt ttatttttat aatcaggttc 1365721 acctgcaaaa tgaacaagta aaaggaattg tccgtcaccc tgtcggctat atcgatttaa 1365781 aatgggcaga taaaaactga tggaggcgat tgaggaaata ctgcttcttt atgcgaagga 1365841 gcggtatttt ttctctttct tgcacgtata cgtagggtgc agagcaaatg aaaggagtgt 1365901 tttcgttgaa ttacaagccg aaagcgttga acaagggtga tacagtcgga gtgatcgcgc 1365961 ccgcaagtcc gccggatcca aaaaagcttg acaccgcgct tttattttta gaagagctcg 1366021 gtcttcaggt gaagttgggc aaggcgctga aaaaccagca cggctattta gcgggacagg 1366081 atgatgagcg gctggcggat ctccatgaga tgttcagaga cgatgaggta aaagcagtgt 1366141 tgtgcgcatg cgggggtttt gggacaggac gtatcgccgc gggcattgat ttcagcttga 1366201 tccgcaaaca ccctaaaatc ttttggggat acagcgatat tacgttttta catactgcca 1366261 ttcatcaaaa cacaggtctt gtcactttcc atggcccgat gctcagcacg gatattggcc 1366321 ttgacgacgt tcacccgctg acaaaagcgt catataagca gctcttccag gagacggaat 1366381 tcacctatac agaagagctt tctccgctga ccgagcttgt tcctggaaaa gcggaaggcg 1366441 agcttgtcgg gggaaatctg tctttgctga cgtctacact gggcacgcca tttgaaattg 1366501 atacgagagg aaagcttctg tttattgaag atattgacga ggagccttat caaatcgacc 1366561 ggatgctgaa tcagctgaaa atggggggga agctgacgga cgcggcggga attctagttt 1366621 gtgattttca caattgtgtc ccggtgaagc gagagaagtc tctctcgctt gagcaggtgc 1366681 tggaagacta tattatttct gcgggcaggc ctgctctgag aggatttaaa atcggccact 1366741 gctcgccaag tattgccgtt ccgatcggtg cgaaagctgc tatgaataca gcagaaaaaa 1366801 cagccgtaat agaggcgggc gtttcagaag gggcgctgaa gacatgaaaa tcattcgaat 1366861 cgaaacaagc cgaatcgctg tcccgctgac aaagccgttt aaaaccgcac ttcgcactgt 1366921 gtatacggct gaatcagtca tagtaaggat tacttatgac agcggtgcag tcggatgggg 1366981 agaagcaccc ccgacgttag tgattacagg agacagcatg gatagcattg aaagtgccat 1367041 ccaccatgtg ttgaagccgg cattgcttgg aaaaagcctg gcgggctatg aggccattct 1367101 gcacgacatc cagcatcttc ttacaggaaa tatgagcgcg aaggctgctg tagaaatggc 1367161 tctatacgac ggctgggcgc agatgtgcgg gctgccgctt tatcaaatgc ttggcggata 1367221 tcgagatacg ctggaaacag attatactgt cagtgtcaac tcacctgaag agatggcagc 1367281 tgatgccgag aattatctca aacaaggctt tcaaacgctg aaaataaagg tcggaaaaga 1367341 tgatattgca acagatatcg cccgtatcca ggaaatcaga aaacgtgtcg gatcagctgt 1367401 gaaactgcgt ttagacgcta atcaggggtg gaggccgaag gaagcggtaa ctgccattcg 1367461 gaaaatggag gatgcgggcc taggcattga gcttgtcgag cagcctgtcc ataaagatga 1367521 tctcgctggg cttaaaaagg tgacagatgc aacagatacg ccgattatgg ctgatgaaag 1367581 tgtttttaca ccgcgccagg cgttcgaagt tctgcaaacc cggagcgcag acttgatcaa 1367641 tattaaattg atgaaagcgg gcggcatcag cggagcagag aaaattaatg ccatggcgga 1367701 ggcctgcggg gtggagtgta tggtcggcag catgatcgaa acgaagctgg gcattacggc 1367761 cgcggcgcat tttgcggcaa gcaagagaaa catcacacgc tttgattttg acgcgccgct 1367821 gatgctgaaa acagatgtat tcaatggcgg cataacatat agcggcagca cgatttcgat 1367881 gcctggcaaa ccgggcctcg gaatcatcgg ggctgcgctt ttgaaagggg aaaaagagca 1367941 atgatgcaca ctgtcatatc agcagtggcc aacatctgga cagcgcctga ttcacctcgt 1368001 ccgtctgatc aattcatgct tcaaccgact gtaatgatca gagactggct ggagcgcatg 1368061 acgtatgatg aacggcttgg attatgtaca gacaatgtaa tccaaactca ggttctcttt 1368121 ggcgaaaagg tacttgtgac ggcggaacag ggggaatggg tttctgtgat cgtgcctagc 1368181 cagccatccc gaaaggatcc gcgcggatac ccgggctgga tgaaaaagta ccagctggaa 1368241 aaaacaaagc ccatccatac acaacacgat gtgatgatca gcaaacctgc tgcctttttg 1368301 tacagaagca atggggaaaa ggagatcgaa ttaagctttt tgacagttct gccccttatt 1368361 gcaaaagaaa acggatattt taaggtttcg accgtttttg gggaaaggtt tgtgaggcaa 1368421 agtgatgcag tgcctgtcag ccaacagaaa gggactgctg aagacatcat tcaaacgggt 1368481 gcgttttttc ttggccttcc ctacctgtgg ggagggatca gcgggtttgg gtttgattgc 1368541 tccggattta tgtacagtat atttaaggcg aatggataca gcatcccccg tgatgcggga 1368601 gatcaggcta aggcagggaa gggtgtcccg cttgatgata tgaaagccgg tgatctgctg 1368661 ttttttgctt atgaggaagg aaaaggagcg attcatcacg tcggtctgta tgtaggcggc 1368721 gggaaaatgc ttcattctcc aaagacaggg aagtcaatcg aaatcctcac attaacagag 1368781 acaatctatg aaaaagaatt atgtgcggtg cgccgctgtt tttcagaata aggagggaga 1368841 caaatgaggc gactgccttt gttagaggtc agccagctga aaatgcattt tgacgcaggg 1368901 aaaaagcgga cagtcaaagc tgtcgacggg gtcacctttc agattcgtga aggagaaacg 1368961 ttcgggctag tcggggaatc agggtgcggg aaatcaacct tggggagagt gctgatgcgc 1369021 ctttatcagc cgacagaagg aagcgtgaca taccgcggca caaatcttca tgcactaagt 1369081 gaaaaagagc agtttgcctt caaccgcaaa ctgcagatga tttttcagga cccttatgct 1369141 tcacttaacc cgcgcatgac cgttcgagaa attattttgg agccgatgga gattcataat 1369201 ctctacaata cccataaagc acggcttctc gtcgtggacg agctgcttga ggcagttggg 1369261 cttcaccccg attttggcag ccgttatccg catgaattca gcggcgggca aaggcagaga 1369321 atcgggattg cgagagcact gtcgctgaat cctgaattta tcgtggcgga cgaaccgatt 1369381 tctgcacttg atgtctctgt tcaagcgcag gtggtcaacc tgctgaagcg gcttcaaaaa 1369441 gagaaagggc ttacgttttt attcattgcc catgatcttt cgatggtgaa gcatatcagt 1369501 gacaggatcg gtgttatgta cttaggacac atgatggaaa ttacagagag cggcaccttg 1369561 tatcgtgaac cgctccatcc ctatacaaag gcgcttttgt cctcgattcc gattccagat 1369621 cctgaattgg aggacaagcg tgagcgtatt ctcttgaaag gggagctgcc gagcccggtc 1369681 aatccgccaa gcggctgcgt gtttcgtacc cgctgtccgg aggcgatgcc tgaatgtgga 1369741 gaatctcgtc cccagcttca agaaatcgaa cccggccgtt ttgtcgcttg ccatttgtat 1369801 cgaaatgctg aaacgaagga aaaagtaaga taaataaaaa gagtggctcc tttttactag 1369861 agccactcca tttgtttata cttgatgtaa aaactttaca caaaccgggt aagggacaga 1369921 aaccgttgat gggaggagtg tcaatcggcc ggtttctttg tctctttcaa acaagacaag 1369981 gttgcctgtt tcttcatttg aagcaacgag gaacccttcc gttgggtcaa atacaaagtc 1370041 acgaggccag tttccttctg tcgacactct ttctacgaaa gccagctctc ctgaatattg 1370101 attcacttca aatacggcga tactgtcatg gccgcggttt gcgacataaa caaaacgtcc 1370161 gtcctgcgtg acatgtattg cgcttccctg gctgttatct gtaaaatcat cagggatggc 1370221 agaaacgact tggatttctc taaattcgcc ggctgtcggg ttgtattcaa gcgcaatcac 1370281 ttcattgctt aattctgtca tgacataagc gtatttttct ttcggatgaa aagcgatatg 1370341 gcgaggtcct gcaccgggag cgaaggaatg gcttccggat tcagtcaaca caccgtcttt 1370401 aagcttatag gtgtagagct tatctatacc taaatcaacc gctaccacat aattgtgttc 1370461 aggtgtgaac cccgcgtagt gtgtatgcgg tttttcttgt ctttcgtgcg gcccttttcc 1370521 tgtgtgagcg gcctctgaaa caggtgattg caagctgccg tcttcctgaa ccggaaaaac 1370581 gtgtaccttc ccgctgtgat aattggcagt cagtacgaat tgattttgat catcaacgct 1370641 tacgtggcat ggcgaagggc catcaattaa ctgatgattc agaaatgtca attcgccgct 1370701 gtttttatcg atttgatagg cagcaactcc gccttggccg tctgcttttt cgatggaata 1370761 aaggatggtg ttgtttttat tcgtcgccac atatgtcggg ttgcccagct tagcggccag 1370821 ctttggctcg ctgagtgctt ttttctcagt atcaagctca aatgaataaa ttccttcgct 1370881 tccgcctttt gtatatgttc ccacatatcc tatgtatttt gtcatgcgat ttccccctta 1370941 aaaatgatgt cacctctata ttaacgtatc ttgataaaat aagctgttca aaacatgaaa 1371001 aaggggaaga ttcttcattc gcctcgaatc agcggcattg tgcagcacct gaaggagccg 1371061 cctgatttaa taatttctga caggtcaatt tcgataatgt gatagcctct tttcgatagc 1371121 tgttgattga catggcggtt gccagggaga ctgatgatcg ttttttttcc gattgaaagg 1371181 acgttggtgc caagcgtaaa ttgttcgtcc tcgggcacct caataagatc ataacgtttt 1371241 gccagcatat cggctgcatc tggctcaatg gcctgtgaat aaattaacgc ttcgctttca 1371301 gatataatgt taaatacgca gtccaaatgc aaaaattttt catgaagctt cactggaacg 1371361 atcgtatatt caggaagtgc ctcttctagc tggccgatag ctgaaatgtc ggtgcgctgg 1371421 ctgattccga catagacaat gtcatcatcg ataatgacgt ctccgccttc aatactcgta 1371481 tcaagcatgc gggtgtaaga gataccttgg ctgtgaaaaa aatcttttat aacggcttct 1371541 tctccttggc gaatcggttc agtcatgctt gacagaaagg ctttttctcc gatgacaaat 1371601 cctatgtccc tagtaaaaac ctgttctggg agtccgtcgc gaacgggcaa aaggacgacc 1371661 tcaacgttgt gtgacctaag tgcctccact aagcggctgt gctggtcgtt agcggttttt 1371721 acatgaatat tgtcatcttc aaaatgtttt tgtgtttcgt ttataacatc ttttatggtc 1371781 atgtgctcag gtttgcataa gatcactttt tgaagtgtgc cgtattccgt tcggcatacc 1371841 gttttgtgct gagatttcgg gatggatacg tccatttgtt tttcctccta aagtgtgaag 1371901 aatacattta ttattccctc atcatgaaaa tcattaaacc attttaaatt ttagacaaat 1371961 ggaagagaat attgtttaat aggagaatat aagtgcattt agctaaaaga tcagacatca 1372021 aaggggagaa aggtatggaa acaccggaaa caagattttg taaagagtca aaggttgtga 1372081 aaaccagcag ggtgttcccg cttgacacga acaaccataa tacgctgttt ggcggaaaat 1372141 taatgagcta catagacgac attgcctcta tttcagcggc gcgccattgc agacgtgaaa 1372201 cggtaacagc ttcaatggat tctgtagatt ttttaaagcc gatcgggcaa aaggattctg 1372261 tctgcctaga gtcatatgtg acatgggtcg gcacatcttc catggaagta tttgtgaaag 1372321 ttattaagga gcatttgatg actggcgaac gggaactcgc tgccacatcc tttttgacat 1372381 ttgtcgcatt agattcaaat ggcaagccgg tgcctgtacc gagggttgta ccggaaacag 1372441 aagaagaaat catgctgcat aatacagctg tacagcgtgc taatgaacgt aagaaccgca 1372501 agagacacag ccaggcgctt gcaaatgcgc tcggaactga taagccttgg tgaacgttaa 1372561 acccaaaaca taagttgttt tgggtttttt tgtacttttc aatggtgatt attacaatgg 1372621 ttagtccgtt tttgctaggg gattctataa aaaagcaaca aatgtcatgt taaattgata 1372681 attttgtgac aactttatta aagattcatt ttagatatat cttttattcg taagatcatg 1372741 tattttaaag atatatttta aatacatctt ttcgaaagga ttgtttataa aatgttagat 1372801 aacaaaacaa tcgaaattat taaaagcact gtacccgtat tgcaacagca tggagaaaca 1372861 atcactggcc gtttttacga tcggatgttt caagaccatc cagagctttt gaacattttt 1372921 aatcaaacaa accaaaagaa aaaaacacag cgaactgcac tggcaaatgc cgttattgca 1372981 gctgcggcaa acattgacca attaggaaac atcattccgg ttgtcaaaca aatcggccac 1373041 aagcaccgca gtatcggaat taagcctgag cactacccaa tcgtcggtaa atatttgctg 1373101 attgcgatta aagatgtatt gggagacgct gcaactcctg acattatgca ggcatgggaa 1373161 aaagcgtacg gagtcattgc tgacgcgttc atcggaattg aaaaagacat gtatgaacag 1373221 gctgaagagc aagccggcgg ctggaaggag tataagccat tcgttatcgc aaaaaaagag 1373281 cgggaaagca aagaaattac atccttctat ttgaaaccgg aagacagcaa gccgttacct 1373341 gaattccaag cagggcaata tatcagcatc aaagtgcgga ttcctgattc tgaatatacg 1373401 catatccgcc agtacagcct gtctgatatg ccgggaaaag actattatcg aatttcagtg 1373461 aagaaagatg gtgtcgtgtc ttcctactta cacgatgggc tgcaggaggg agattcaata 1373521 gagatcagcg caccggcagg ggactttgtt ttagatcatg catcacaaaa agatctcgtt 1373581 ttgatcagtg ccggagttgg cattacacca atgatcagca tgctgaaaac atctgtttcc 1373641 aaacagcctg aacggcaaat tctgttcatt catgcggcga aaaacagtga atatcatgca 1373701 ttgcgccatg aagtagaaga agcagcaaaa cattctgctg ttaaaacagc atttgtgtat 1373761 cgcgagccga cagaggaaga ccgtgcaggt gatctgcatt ttcatgaagg acagattgat 1373821 cagcaattcc tcaaagaact gattgccaac acagatgcgg attactatat ttgcggttca 1373881 ccgtcgttta ttacggcaat gcataagctt gtatcagagc tcggatcagc gccggagtct 1373941 atccattacg agctattcgg cccgcaatta agtttggcgc agtccgtttg aacacataca 1374001 tgaaactctt ctcctttcag agaagagttt tttattgaga tataagaagg cagacaagcg 1374061 ccggtttcta catccggaca atcacagacc cgctgccatt tgtgcataca cggttttgct 1374121 gttcttgcat tgttctcagc aattcattgt ttacctcaat cgctctaatt agttgcttca 1374181 ttcttagctc caaaccggcc agcctgtcga ttgtttgctg ctggtagccc tcgggttggg 1374241 gagccaatgg cagatcaaag ggccaaaggg tattcgactt ctgatttttc atattgcgta 1374301 ttgcgcctcc aatcggtgtc actttctatt atgttatgtt caggcgatat gcacgttcgc 1374361 ctagacactg atgcatagag ggcctgccac ggggcacaat aggctcaata tgaccagcgg 1374421 atggaggtaa agatcggtgt tatggatggt atgggtattt ttactgaagc cagttatcgt 1374481 attttcgatt gcatatattt tgtttcggct tgccggtaaa aaagctgtgt cacaaatgaa 1374541 caattttgac ctgcttttga ccttcgcaat cggaaccatt atcagtgagc cgatccttac 1374601 atccaagctg ccgatgtcaa tttattatgc gggtgctttt ttggtgcttt atcttatcat 1374661 gagcaagctc tctttatcta ataaatggcg atggctccta gtcgtgagcc cgactgtcct 1374721 aatccgaaac ggggatattg atgaacgcgg ccttcgtaaa gaaaggctga ctgttaatga 1374781 gctgctcgga aagctgaggg aaaagggcta tgccgacccg gctgacattg atcttgctat 1374841 cattgaagaa acgggagaag taagcgtcat cccgaaagag gaagcgagag cggtgcaggt 1374901 gcgggatttg aatatggaag ctgaacggaa ttttatcccg attccgctca tactggatgg 1374961 cgaaatcctt gatcataatt tgaaatatct ccaaaaaaac cgatcctggc tgtttgagaa 1375021 gcttgaggaa aaagggtaca gccccaaact gctgtcttcg attatccttg gcacgatgaa 1375081 tgcacgcggt gatatatccc ttgatttaaa taccgctaat gaaccgcagc atgatcctta 1375141 cttatataaa ccgggaaata acaattaaga tggctctctc ttgtaatgag agcttttttc 1375201 ttttttaaag ggaatttttg tttggtgtca aatgtaccta gttaggaggg gaactgaaca 1375261 tgaaggactt atccataaga aacgacatgg cgccaacggt cagtttgctg tattccgcag 1375321 tggaagaaaa cagtctccgt ctggcttcca tcgtaagcca tatgacacac agtgaacttt 1375381 actataaggg gcgctgccaa acaaaaaaca gcacggctca gcttttgcac catatcacaa 1375441 atgttgatat cagatgggtc tggcgtatca aggaaaatcg gatcccggac catattgaac 1375501 aggcatacgg cccgatgaca gatgaaagcg gacggctgcc tgaaccggtg aatcagccag 1375561 acttagatga actcctgaaa agacatcagc atgtagtaga gaagctgaaa tcggtatgct 1375621 tcactttaac tgaaaatgct ttgaaccagc cgctttcctt cgaaggtgac accgcgacga 1375681 tacgatgggg aatttggcat atggcagatc ataaccgcta tcatcaggca catattgaag 1375741 ctctcaaaaa agaatggaag caggatgtgg cgaagtatga acgctaaaac gaagcttgtg 1375801 actgatcgaa ttcgtttgcg ctgtatggaa gatcgggatc aagccacttt gtttgggctg 1375861 ctttttaatg atcctgacgt catgacatat tattccggtt taaaagataa gaggcaaacc 1375921 cgcgagtggg tcaattggaa ccaacgaaat gaaaaagggt acggcgttag tctgtggatc 1375981 gccgaagata agcggacagg ggagtttttg gggcaatgcg gcatcgttcc ccagcagatc 1376041 gaaaatcaaa ccgtaatgga aattggctat atgtttgccc gccgccactg ggggaacggc 1376101 tatgcgcaag aagcggctcg ggcctgtctg gactatggct ttaacgagcg gcagttcggc 1376161 aaaatggcgg ctttgattga tccgggtaac aaagcgtcca tacgggtagc ggagaaaatc 1376221 ggcatgcatt acagcaaaac gatcagaaaa tggaataaac cgatcgcggt atatgaaaga 1376281 aaatcttaca attgaaagat agagctgagt ttagtatcat gatatcatgt aaagttttct 1376341 agggttccgc atgtcaattg acatggactg gtccgagaga aaacacatac gcgtaaatag 1376401 aagcgcgtat gcacacggag ggaaaaaagc ccgggagagt caatctcatg tgagacgact 1376461 gtccggggtt tttttgtttt cggagaatct taatagatag aaaggaatga ctcaaaatga 1376521 aatggggatt ggtcgtgctt gccgctgttt tcgaggttgt ttgggtgata ggcttaaagc 1376581 acgctgactc agccttaaca tggagcggca ctgccatcgg catcatattc agcttttacc 1376641 ttctaatgaa ggcgactcac agtctgcctg ttggtaccgt gtatgccgtc tttaccgggc 1376701 tcggcacagc gggaacagta cttagtgaaa tcgttctttt tcatgaaccg gttggatggc 1376761 cgaagctatt gttaattggc gtgctcttaa tcggtgtaat cgggttgaag cttgtgacac 1376821 aggatgagac agaggaaaaa ggaggcgagg cataatgctg cactggatca gtttattgtg 1376881 cgcgggctgt ttagaaatgg ccggcgtggc ccttatgaat caatatgcga aagaaaaaag 1376941 cgtgaaatgg gtgctgttga tcattgttgg ttttgccgct tcattttcct tgctgtcgta 1377001 cgcaatggaa accactccga tgggaacggc ttacgcggtc tggacaggaa ttggcaccgc 1377061 cggcggggcg cttatcggca tcctctttta caaggagcag aaagacgcca aacggatctt 1377121 ctttatcgcg ttgattttat gctcagcagt tggtttaaaa attctgtcat aaattgattt 1377181 ttatcaaatc ttcagtataa tggataaata gtttagactt acaaagataa gagggattat 1377241 tcatgaaatc atatatgact cagcggttgg acgaataccg tgacggaaat gaggataaag 1377301 gtcggctctt ggtcagctgc cccgatcagc cgggtatcgt ctctgcagtt tccgcgtttt 1377361 tatttgaaca cggtgccaat attatagaat caaatcaata tacgacagac cctgaaggcg 1377421 gccggttctt cctgagaatc gaattcgact gcgcaggcat tcgtgaaaaa aaatcatcac 1377481 ttcaggcagc gtttgcctct gttgcggaaa aattcgacat gacatggagc ttaactttgg 1377541 cgagcgaact gaagcgtgtc gccattttcg tttcaaagga gctccactgc ctgcatgagc 1377601 tgatttggga atggcaaacc ggcaacctga tggcggagat cgctgttgtc atcagtaacc 1377661 atgaggaagc gagagagctg gttgagcgcc tgaacattcc attccactat atgaaagcga 1377721 acaaagacat cagagcggaa gtcgaaaaga agcagcttga actgctggag cagtacgatg 1377781 ttgatgtgat cgtgctcgca cgctatatgc agattctaac tcctgatttt gtttcggctc 1377841 atccgaatcg catcatcaat atccaccatt cattcctgcc agcttttatc ggtgcgaatc 1377901 cgtacaaacg ggcctacgag cgcggcgtga aactgatcgg tgcgacatct cattatgtga 1377961 caaacgatct tgatgaaggg ccgatcattg aacaggatat tgagcgtgtg gaccaccgcg 1378021 ataatgcgga agcgctgaaa aacatcggaa gaacaattga gcgcagcgtg cttgcccgtg 1378081 ctgtgaaatg gcatttggaa gaccgtgtca tcgttcatga aaataaaaca atcgtcttta 1378141 actagactgc aagaggcccg cgcaatgcgg gctatttttg atgacaaaaa accttgacaa 1378201 gtgtcttttt tctttgcata atataaaaaa atcattgagc gttgaagagg attagtaagc 1378261 agacctttct gtgacagaga gcaaaatgaa tcgctgaaac attttgccgc atgaaacctg 1378321 ccgaacctgc cttggagtcc tagggggaaa acctaggcgc ataacctggc gttacaggag 1378381 agcggagcgt gcacaagcgc gttcaatcaa ggtggtacca cggaaaccca tttcgtcctt 1378441 atgaatcagg atgaaatggg tttttttatt gtagaagagc cgcggaggag aataaatgaa 1378501 aaaacaaaga atagtagtga aaataggaag cagttcgctc acgaatagca aaggaagcat 1378561 tgatgaggca aaaatcagag agcatgttca ggcgatttcc gtgttaaaaa aagcggggca 1378621 tgaaatgatt ctgattacct cgggtgccgt agcggcgggg ttttccagcc tcggttatcc 1378681 atcccgtccc gttaccatca aaggaaaaca ggcggcggcc gcggtcggac aaacactgtt 1378741 aatgcagcaa tatatgaatc aatttaaaca atactcactg actccgggac aaatcctttt 1378801 aacgagaaat gatttttcga aaagagaacg gtatcgaaac gcgtatgcta cgataatgga 1378861 attattagag cggggcgtca ttccgattat caacgagaac gattctacat ctgttgaaga 1378921 attgacattc ggagataatg atatgctttc tgcgttagtc agcggattga ttcacgcgga 1378981 ccagctcatg attctcactg acattaacgg actgtatgat gccaatccaa atgaaaatcc 1379041 tgaggcgaaa cgatttgatt atttgccaga gatcacgcct gaattgcttg gatatgcagg 1379101 ttcagctgga tcaaaggtcg gcaccggcgg aatgaaatca aagctgttag ccacacaaac 1379161 cgcgctgtct ctgggagtga aagtattcat tggaactggc agcggagagc aaaaacttgc 1379221 ggacattttg gacggcaggg gagacggcac ttatatcgga gacaaagaac tatcttcggt 1379281 taacaacaca aggcagtgga ttcagttcca ctcgccgata tcgggagaaa ttatcattga 1379341 tgcgggtgcc gaagaggcga tgatccataa tggaagcagc cttttgcccg ctggagttgt 1379401 gggcgtgaac ggaagctttc cgaaaggggc ggttgtggaa gtcaggggac cgggcggcgt 1379461 gatcggcaaa ggccaaactc attactcctc cgaggagatt atggaggcta aaggcaaacg 1379521 cagtgacgaa cttgattttg agaaaacgtt tgaggttatt cataggaatg actgggtcaa 1379581 tgtaaaagac taggaggcgg aaaaatgagt gaagtttctg taaaagcgaa gctggcgaaa 1379641 gaagcagcag ccgaaatgat catgaaaaca acagccgaga aggatgaggc gctcagcctc 1379701 attgcaaacg gactccgcaa agaactggat tttctcttgg cggagaatgc aaaagacatt 1379761 gtgaacggaa aagagaatgg tttaacaccg gacatcattg accgtctctc attggatgag 1379821 aaacggatac gcgatatcgc ggacgcggtg gagctcttaa tcgacttagc ggacccaatc 1379881 ggcgactctc ttgaaacgat tgaaaaagaa aacggcctgt ttattgaaaa aatccgtgtg 1379941 ccgctcggtg tcgtaggaat gatttatgag gcgaggccaa acgtcacagt tgatgcggct 1380001 accctttgcc tgaagacagg gaacgcggtt gtgctgcggg gaagctcctc agccatccac 1380061 agcaacaaag cgctcgtcag tgtcatttac agagcacttg agcaatcagc gcttccgatt 1380121 cacgctgtgc agctgattga ggatacgagc agagagacag caaaagagct ctttacgtta 1380181 aatgatggct tagacgtatt gattccgcgc ggaggcaaga aactgattga tctcgttgtg 1380241 agagaatcaa cagttcctgt attagaaacg ggagcaggaa actgccacat attcattgac 1380301 gaaacagcca aaccgcaaat ggcagaaaag gttgttgtaa atgccaaaac gcagcgccct 1380361 tctgtatgca acgcgattga atcattgctg attcacaagg cttgggcaag acagcacgga 1380421 aaagaattgc tggaccagct ggaaaacgcg ggagttgaaa ttcgcggtga tgaattggta 1380481 tgtgaacttc atccttcaag caaacaagca tcaaaagaag attgggaaac cgaattttta 1380541 gcgcctgtcc tcagcgtaaa gacggttgaa aacgtccaag aagctgtaaa gcatatccaa 1380601 caatacggca ccaatcattc tgaagcgatt ttaactgaaa atgacaaaaa tgcggtatat 1380661 tttcaaacgg ctgtcgatgc tgccgctgtc tatcataacg cgtcaacccg ctttaccgac 1380721 ggctttgaat tcggctacgg agccgaaatc ggcatcagca cgcaaaagct tcatgcaaga 1380781 ggaccgatgg ggcttcctgc actgacttct acaaaataca tcattaaagg aactgggcaa 1380841 atccgtgaat agcggggtaa tgttcaatga aaaagcttat ctcattacga gataagcttt 1380901 tttatacgcg aaaaattgac atttcaaatt taattgtgta caatttaatt gtataaaata 1380961 tattggggga atgaaaaatg agtcagccat tatttaccgc aactgtttca gcggtaggag 1381021 gaagagaagg aaaggtcatt tcatcagacc gcgttcttga gcttgatgtc gcaatgccgg 1381081 ggacaccgag agccaagaaa ttagaaaaag cgacaaatcc agagcagctg tttgcagcag 1381141 gttatgcagc ttgctttgac agcgccctgc agcttgtcgc aagaacagaa cgggtaaaag 1381201 tagagacaga ggttacagca aatgttagcc tgttaaagga tgaagcggac cagggctata 1381261 agctgggtgt gacgctgcaa gtaaaaggag aaggagtcag tgcatcagaa ttggaggcgc 1381321 ttgtgaaaaa agcgcacggc gtctgcccgt actcaaaagc aacctccgga aatattgatg 1381381 tgacacttga agttgctgaa taaataaaaa gaggatgcct gtacaaggca tcctcaattt 1381441 ttttgatgaa gtgtttccag taatgtatat agagcggact ttaactgttt gagatcctcc 1381501 ccagactgct ttgagagccc cagaattgtc cctggaatgt caaccgcttt ttcttttaat 1381561 aacgctccgt cctctgtcag gctgatcaac acggaccgct catcctcttc agatcttttt 1381621 ctcgtaatca aaccctgttg ttccattcgt ttaagcatcg gagtgagcgt tcctgaatct 1381681 aaatacagct gttcgcccat ttttttgaca gtaagcgttt catgttccca taacaaaagc 1381741 aaagccaaat attgagggta tgttatattc agcttatcaa gcagcggctt gtattgcttt 1381801 gtcatctccc gcgaactcgc atatagcaaa aaacaaagct gattctccaa tttcatatga 1381861 tcaaatttat tttccatttt gttcaccaac tcttttttgt cattcgattc tattgtatct 1381921 gaaaaacctc acttttccta ttctcggcaa acatagcatg tttaaaaaga tcagaaaggg 1381981 aaatataaca actagataca aataaggagg ttgggaaata tggcactatt tacagcaaaa 1382041 gtaaccgcgc gaggcggacg agcaggacat attacatcag atgacggtgt tcttgatttt 1382101 gatattgtca tgccaaatgc caaaaaagaa ggacaaaccg gcacaaatcc ggaacagctc 1382161 tttgcggcag ggtatgctgc atgcttcggc ggcgcgctcg aacacgtagc caaagagcag 1382221 aatatcgaaa ttgattcgga gattgaaggg caggtcagcc tcatgaagga tgagagcgac 1382281 ggcgggttta aaatcggtgt cacacttgtt gtgaacacga aagatttaga tcgggaaaag 1382341 gcacaagagc ttgtcaacgc cgctcatgaa ttctgtcctt actcaaaggc aaccagagga 1382401 aatgttgatg taaaactaga attaaaataa tgaccggcat cctgaggatt ctcaggatgt 1382461 tttttggtgt cggacatgcg gggcgggcac agatttatga taaaacttca gagaagcgtt 1382521 tgaagcatgc ctttaaacca aaagttacag atgaagcggg tggctggcac ggtgtctgcc 1382581 gtgctgaatt gcgcgtatat gctgttttgt atttgcacag ggcatagcgg ctacttggag 1382641 aaataacaag gaccaggccg cgcatgcctg atccttttaa tattctttct tattggcgaa 1382701 gttccgccat gcttgaaacg gggataaatg ctctgttagt gtcacttgat aaaaggggat 1382761 cgttctttct tcagcaggtt tatcaatttc tttataaatg aatgaatcat caaacccggc 1382821 ttcggcagcg tctgtgtgct cagctgcata gaaaacggct ttaggccggg cccagtagat 1382881 ggcgcccaag cacattgggc atggttcaca gctcgtatac aaaatgcagt catcaagctg 1382941 gtaggctcct agcaccttac aggctttccg aatagctgtg acttccgcgt gggcagtcgg 1383001 atcattgctt gttgtgacgt tgttctgtcc ctctgcaata atggctccgt ctttcacgat 1383061 aacggctcca aaaggcccgc cgattcctgc attcactcct tcacatgcga gagtgacagc 1383121 ccgttttaag aacgtttcat gattcatccc aatccctcct gtcaatagag tgttattagt 1383181 atagccgaaa agaatgcaaa gaacattctt aaaaaagtgc aaaataaaca aagtatttgg 1383241 gggatttgct aaataagaaa ccgattgtgg ctgtattata gaaaaaaacc atctgccaaa 1383301 tgcagatggt tttttcaaat tatactagct gtgtctgctg tgctcttgcc tgttttgcgg 1383361 cttcaaccat atttttcaat gctgcaaccg tttcttcctg ctgtcttgtt ttcaatccgc 1383421 agtctggatt tacccagaag cggtcagtcg gacagacggc aagcgcatca acgataatat 1383481 tgtacatttc ttcagttgac ggcacacgag ggctgtgaat gtcatataca ccaaggccaa 1383541 gccctttcaa atacgggtgg ttttttaagt aatctaaaaa tcctccgtgg cttctgctat 1383601 gttcgattgt aatcacatcg gcatcaagat cattgattgt atcaacgata tcttcgaagt 1383661 tgctgtagca catatgtgta tgaatttgtg tctcgttttt cacggaagaa gtggttaatc 1383721 tgaaagcttc tgccgcccaa gtcaaatact catcccaatc gcgggttttc aatggaaggc 1383781 cttcacgcag cgctggttca tcgacttgaa tgatttgaat gcctgcgtct tcaagcgctt 1383841 taacttcttt gcgaagggca agcccgattt ggaaggcgat ttctttcctc gagatgtcgt 1383901 ttcgagggaa agaccagttt aagattgtaa ccgggcccgt cagcattcct ttcacatgct 1383961 tggaagtcaa tgactgtgcg tagactgtgt ctttcactgt catcggttca ataaattcaa 1384021 catctccgta aatgactggc gggcggacac agcgtgagcc gtatgattga acccaggcat 1384081 atttagtgaa ggcgaaaccg gccagctttt caccgaagta ttcgaccatg tctgtccgtt 1384141 caaattcgcc gtgaacaagg acatcaagct ccaattcttc ctgaatatca atccatcttt 1384201 ttgtttccgc attgataaag ttttgatact gttcatcgga ccactcagct ttccgccatt 1384261 tttggcgtgc gctccgcact tcagcagact gcgggaagct gccgatcgtt gtcgtcggca 1384321 aaagcggaag gccgagagat tcattttgta gggctaaacg ttcttcaaac ggaatcgggc 1384381 gcttgaagtc tttatcagtt aattgctcaa gctctttctt ttgttcagaa ttggcgcctg 1384441 ttgcaaactg tttaagcgcc tggatatcag ccttagcctg ctgaatctct tcgctgatcg 1384501 ccgcttttcc tgatactaag ccttctttca aagctgtcag ctcggccagc ttttcttttg 1384561 cgtaggataa tccgttcaat aggtcttttt ccaaatgctc atcagggtgt ttcgctactg 1384621 gaacatgcag caggctgctg gaaggctgaa tccacagttc atcaactttt gcaatgctga 1384681 gaatatcaag aacggcatcg agacgctctt caaggtccgc tttccaaatg ttgcgtccgt 1384741 cgataacgcc ggctgccagc actttatctg tcgggaagcc atgtgtttta agctgttcca 1384801 ggtttctgcc tttgtcgtga acgaaatcaa ggccaattcc ctgaaccggg taagagatca 1384861 gctcttcata agcatcaaca gaatcaaaat acgtctgcaa aagcacattc aaggatgaaa 1384921 gctcacttgt aatgctttca aataattctt ttgcgccgcg tacatcttca ctagaggcgg 1384981 taacgagcgc cggctcatcg atttgaaccc attttacgcc ttcttcttca agctctttca 1385041 aaagctgtac atataatggc acaaggcgtt tttggatcgc ttttgcttca gacggttcat 1385101 agcctttagc aagcgtaacg aacgtataag ggccgacaat cacaggcttt gtttccacac 1385161 cgtattcctg tttgatccgg cgataatctt cgagttgttt gtttcttgtc agacggaact 1385221 caatgctctc gtcatattcc ggaacgatgt aatggtaatt tgtattaaac cattttgtca 1385281 tttcactaga tacagcgtct ttgattccgc gggcgatagc gaagtatgta tcggtagcgt 1385341 cagtcaaatg tctgaaccgt ttcgggatcc agttgaagct gactgctgtg tcgagtacat 1385401 ggtcatactg tgtgaaatca gaaacaggca caacatcaat ctgctggtca atttgtgttt 1385461 ttactgcgga taaaaatagt tcgtcgattt gcttcaaaaa cgtatcttta tcagtactgc 1385521 ctttccaata cgcttcaagt gcttttttcc attcccggtt cagtccgatt ctcggaaatc 1385581 ctaaattcga tgttttgatg gttgtcattg tttctcctcc tttatatgta aaacactctc 1385641 tttcacccgc ggatacaggc tgctaagagg ttttctcaca acaaaaagcc tctttcccat 1385701 gagagaaaga ggcttttcta cgtaaaacac tgcctctctc atctctcaga cacaatctga 1385761 tggaattagc accgtgcctt atgagacatc agtctcggcg cgaaaagcag tgcgccccat 1385821 ttcacaatgg tattacggtc ggttgctgtt ggggtcaaaa ggccaatccc tcgcccaact 1385881 ctcgataaga gaaaatgtta ttaatttttt gaaaagttga atcatttgtt ggtaatctta 1385941 acagtaattc aaattcattg tcaacataga atttgaaatt tttatttaca tgatgtggtg 1386001 tatattatat aagaaaaata atcttatagg gtcaacaaat gtgattgctc tgctttttct 1386061 gcgagctcat caggagctgt taaatacagg aatccattgc ctgccagcgt ttttgcaata 1386121 tcaagaggaa gtgtcctgcg gattagctgt gcgaaaacct cagattcaga aagctttctt 1386181 tgaaatgatt cttcttcata gcttttgatt aaagcaagcg caccgctgac atgaggggca 1386241 gccattgaag tgccggtcag cttaccgtac ttcttgttgg gaagggtgga taagatgttt 1386301 tctcctggtg ccacaaggtc aatctcttta ttcgcgttag aaaattctga taattctcgc 1386361 gctacagaaa cagatccaac tgcaatcact tcattataag ctgcggggta ggaaagctct 1386421 tctgtgcgtt cgtcgccgtc accttcattt cccgctgcac aaacgacaag cactccgttt 1386481 ttcactgcgt ttttcactgc ttcttttagc tctggcacat cgcttggccc tccaagggac 1386541 attgagatga tgtcgacttt ctgttccacc gcgtagttga tgccgttaat tatccattcg 1386601 tattgtccgc tgccgttctc gccgccaaga accttcacaa tcaataggct tgcctcaggc 1386661 gcgactccgg caatgcctcc gtttgaatca ttagctgcaa ttgttccggc gacgtgtgtg 1386721 ccgtgtccgt tgtagtcgga aatcgcatct tccttgccgc cgtcgtcatc cgtgaagttc 1386781 tttccgccga tgatttgatt ttttaaatca gggtggcttg tgtcgcagcc tgtgtctaat 1386841 acagcaactt taatattttt gccttttacc ccttttgccc acatttctgg cgccttaatc 1386901 actttaatgc cctcaggaag ctcgtttaca tccatgatct gctcattcgt cacatacggg 1386961 atcaagcgga tttcaccatt cataaaaaag ccctcctttt ttatgcttgc aagtggattc 1387021 aagggtgttg cctcatatta tatgaaaaaa gcaagcgctc ggacagagcc atttgaagca 1387081 ttttgaaaaa ataggataca caccaaagaa ttagtaatct tcaaaatatt ggatggcttc 1387141 aacatgtatg actgggattc aactgtaagt caagttataa tagtgttggg gaaaggagca 1387201 gtgtcatgaa actgaatgaa aaattatatg catttttttc agagcatgtg gaacaaatgg 1387261 ccgaggaatg gattgaaacg atggaggaaa gtgatccgaa ttcgctttac gccctacata 1387321 atgcaacagt aacggaagaa ttgaaagagc aggacagaga attttaccgg catctgaatt 1387381 acatgtatgt tttaccggaa aaacaatttc tcgaagagtt tcaagagtgg gtcattgagc 1387441 tgaccaacga tcaaaaacat ctcgacacac cggttcagta tgtcattcgg gagtttatga 1387501 gaaacaggag attatatacg aagtattttg agaagttcgc agaagaaaat gaatcagcgt 1387561 ttgaaccggg agagaagcaa aaatgggcag atttgattgt aaaagtattt gatttcacca 1387621 tttatacatt cgttgatcac gctgaaatga atgccaagca gcaattaaac gcccaaagag 1387681 aaatgatatt ggaattaagc tcacctgtca ttaccctgag caaatcaaca gctctgctgc 1387741 cgcttgtcgg tgacattgat accgaacggg cgaagtttat tctggaaaac acgcttcaag 1387801 cttgtgcgaa aagacgtgtg gagcatctgt taatcgatct gtcaggtgtt gttgtggtgg 1387861 atacgatggt ggcgcaccag atctttaaat tgattgaggc gcttaatctg atcggtgtcc 1387921 ggtcaaccct gtcaggaatc aggcctgaaa ttgcgcaaac tgctgtacag ctggggattg 1387981 acttttcgaa tattactatt aaaaccaacc ttgcccaagc attaaactat catcaataaa 1388041 aaaatccgct atctgtgata gcggattttt tatgatgcga aacataaaga tacgagaaag 1388101 gatcccgcga ataataagag gacgaggcaa aagaacaccc agtcgcgccg gttcacgctc 1388161 aatgtcctgt agtatgtccg gtttctgctt cctgtaaatc ctttcgattc catcgcaagc 1388221 gctgtccgtt ccgcttttct gatggcgctt gccaatagcg gtatggtata tcgttttaac 1388281 gcactgattt tattaatgat gccgctctcc gccgctcctc ctctgatttt atgagcctgc 1388341 tgaatcagct ggacctcatc ctttaacagc ggaagaaagc gaaagcctgc aatgacaccg 1388401 tacgcgagct ttggtgagag cctgcactgc tggacaaggc tcagcataaa tagaatcgga 1388461 tcggttgtaa aaacaaacat catcgataag gcggaaaagc ataaaatacg aaacccgaga 1388521 gagatgccga cagacacatt atcgctgtta atggagatag ggcctgcttg aaacaaaaaa 1388581 ttatccggtg ttgtcggcac ttttccaaaa actgcggctg tccacacgca tccgaatgct 1388641 aaaatcaaaa acggaatcgt aaacaacaac cattttttca atgggattcc ggccgccagt 1388701 aaaacgcccg caacgatgat gatataaaaa catgccggag tgtaagggtt gtaaataaac 1388761 gacagcatga cgacacaaca aaaaaccgcc gccgctttca cagtcggatt aatgagatgt 1388821 aacggttgct tcatcacgca cctcctcttg aaatgccatc cattcatata gaaggggaag 1388881 ggtgagcttt gctttttgaa caagccctgt ttcttgagaa aacaactgcg ctggagatcc 1388941 gtcaaaggcc aggcctgtat cgtgaagcac aagcacgctg tcagcatacg aagagactag 1389001 ctccatatcg tgtgtaatca taaggacagc agttccctct gccttgatac gttgaatcat 1389061 ttccatgcat tcagccgccg tgcgggcatc ctggccaaag gttggttcgt ctaataataa 1389121 aacctttacg tcatgcatga gcatagtagc tacgctcagt cgccgttttt gcccttggct 1389181 gatcgcaaac ggatgatgat cagccaaatg cgcaagacca aaacgctgca gcaggtgttg 1389241 cgcttttttc tcagtttcag catttgcttt ctggccgaac agaagctcgt catacaccgt 1389301 atcggtgacg aattgatgct cagggttttg aaaaacaaat cccatccgtt tacgcaattc 1389361 tttttcttta tatttctgca gcggctgatc atagagaagg attttgccgc tttgcggttt 1389421 catgagactg gccagaactg ataggagcgt cgattttcca gttccgttcg gaccgacaag 1389481 cgccgttaaa gagccttcgc gcaacgaaaa gctgatgtct ttgaaaatcg cctgctgtcc 1389541 tctcgcgaac gaaaggctgc tgacttcaag cacactctcc ccagaagggg ctttcttctt 1389601 tttgacatgc ccggcaggaa taggctcttt gaacagcatc tcttttgata aagtaaacgg 1389661 catactcagc ttttcctgca gatgacagac ctttggaatg gcgatgccca atttctttag 1389721 tgtctccgct tcatgctgaa atagattttt cgtcaggcca tccagtgcct ttttgcctga 1389781 tttgtcgagt acgatcgttc tctcaatcca aggcgcccat tcatcaagct ggtgctcaat 1389841 gacgaggagg ctgaaacctt tttcccgctg aagatccttc atcagatgaa cgaactcccg 1389901 agctgagaaa gggtctaaaa gagaggtcgg ctcatctaaa ataataagct caggctccat 1389961 cgccaaaata caggcgagag ccactttctg cttttgtcct cctgaaaggg ttgagatcat 1390021 tttttctttt aaatgggtaa tgcgtaattt ttctaatacg gcgttgattt tctctgtcat 1390081 ttcttctttt ggaatttgca gattttccag cccgaacgct atttcgtcct ccaccgtcag 1390141 catgcagaac tgctgatcag gatcctgaaa aacgaccccg gcatgctgag taatcgtttc 1390201 ggaggtttca gcatctgtga ccggcttttg aaatagaaat acatgtccgg actgaatgcc 1390261 gtcgcaagcc tccggatata gaccgtttaa acaaagggcg agcgagcttt taccgcatcc 1390321 gctcggtcct aataataaaa cacattctcc tttttgaagc tcaaacgaaa tgtcttgaaa 1390381 aaccggtttc tcgtcttctt cataagagaa gctgagctgc tcaaccgtca gaagctcatc 1390441 aaaggcttgc atgttctgac gcccgcttcc gtttcttttt cagttccttt ccgagtgcca 1390501 ttccgtttaa cacacctgta taagcgagag agtcgctgac agcttttccg agaagccccg 1390561 ccaaaagcgc gccggaaatg aggcggatca caagcataat gagcagataa cctggtgaat 1390621 aggctgcata gccagaaaca aagagatcat agataaagct ggctactgaa gaccccatac 1390681 cggccagcat aaggacaggg agagagtatg ctttccagcg tgttgcaaga aatacagcct 1390741 cagccccgag cccttgaaca atgccaatga cgatgaccat cgggccagac ggatttccca 1390801 gcaggcactc aacgagagcg gcaatgattt cagaaacgag cgccgcaccc ggttttcgaa 1390861 tcatgtacgc ggcgatcaca gaaacgataa accaaatgcc gtaaattggt tcataggcga 1390921 ttggcccaaa catacctgca agtacgtttc cgaaatgtgt aaataataaa taaacaacgg 1390981 caaatacgat actgataacg gacatgatga caatttcttt tactttccag cttttcatgt 1391041 tatccctgct ttctgttttt tcttgatgga ctgttagccg aaagattcac agtcatggtg 1391101 atgtggtttg tttgctgctc agccatgcgg aaaacggcct ccaatgtgct gaatacgtca 1391161 tgcgcatccc cgtcaagctc gctcgcgtaa tggacaccct gtacgaaagt gccttgggct 1391221 tttgcaatgt cgacagcctc cataatcaat cccatataat ccggctcatt cattggataa 1391281 agggcaaatt ggcacggcgc ttccgccttc aagcctcgga cagcatcttc attgacacgc 1391341 ttatcacctt tggaaagata tgtatccccc tgtgtgtcac ccgggcatcc aatggaaaac 1391401 gtgccgttca tgacgatgtg ttgttcgctg tttgctgcat gaaggtaaat ggcttttgca 1391461 gcatcgaata catgatcaat cgatccgcgt aacaccgtgc tgatatggtc ggttttcgtc 1391521 caaaccttgg atgtatctgt ttttttcagc gcagacttga tcacactgat aaaatcatcc 1391581 gtcatcggat ataaagagaa gcgaaaaccg gcgattctgc ttgtaccgca aatatgctcc 1391641 atttctccga cctcctgttt ttttggtaaa ataaaaaact gcatatccta agggaatatg 1391701 cagtcataga tcgattaagc gcacaaaaaa atacaccatt cggtcaacct gcacttcccc 1391761 acgctggtat tatccagatc gggtcataag ggatcaaagc gcgtttcttc cgcgctttat 1391821 ctcagccaaa acagcacccc tagtgctttc cgtatacaat tttttatttt gacatcataa 1391881 tagatgataa gaatcatttt gtaaacaacg aaatcatttt tttcatatag ggacgggaga 1391941 ggatggtcaa atttggaaaa aggacacata ttaattgtgg aagatgaaga aaaaatcgcc 1392001 agggttcttc agcttgaatt ggaatatgaa ggatacagcg tcacgatcaa acacaatggc 1392061 acagaaggtc ttgatgcggc agcggaaggc gggtattcct tggtgcttct tgatgtcatg 1392121 cttccggggc ttagcggact ggaagtgctg cgccgcttga gaaaaacgga ttcgcagaca 1392181 ccggtcatat tattaacggc gcgagacagt attcctgata aggtaacagg tctggacatc 1392241 ggtgcaaatg actatgtcac caagccgttt gaaatcgagg aattgcttgc gagaatcagg 1392301 gcggcgctgc ggcaaaatgg aacaaaaact gaagatatcg gcacctttct tacatatgac 1392361 gatttgcggg tgaacgaaaa aacccgtgaa gtgagacgcg gagacaaaga ggtggaatta 1392421 acgccgcggg aatttgatct gctcgtctat atgctaaagc atccgcagca agtgctgaca 1392481 cgggagcaaa ttctaagctc agtatgggga tttgattata tcggtgatac aaatgtcgtg 1392541 gacgtctaca taagatacat cagaaaaaaa ctggactatc cttacgaaaa acagctgatc 1392601 catacgattc gcggggtcgg ctatgccatt aaggggtaaa cgatgaagct gaagaccaag 1392661 attcatctat acacttcgat atcactgttg attttattaa ttttggttca taccgcagta 1392721 tatctcattt tttcgtctgc gctgacatca aaggatgcgg cccggcttgc tgatgagacg 1392781 gataacattg ccgaagcgct gcgtgccgct gaaacagaag gagtggcttt gcaggatatg 1392841 ctgcaggcct atcttccggc aaatggcatg gtgcgtgtag tgaatggtga tcaaaaagcc 1392901 gttatgacga tcacaaaaga aaaagcctat aaagattttc ctctctcttt tcatagcggc 1392961 gaaacggcag atgtgaggaa acctgacggc aagctgtttg ccgaggctgc tgttccggtg 1393021 atttggaccg atggacaagt cgtgtctctt cagctggttg aaagactgga gaacacagaa 1393081 gagagtctgt ttctgctgaa aatcatctta atcgctgcaa gtgctgctgt ctgcattgct 1393141 tctttttttg caggcagctt gctagcccgc cgaatcatca atccgatcag acgattaatg 1393201 atcacaatga aagacataca gcgagacaaa gaatttaaaa cgatttcttt agaaggacag 1393261 tccaacgatg aattgtatca aatggggctg acatttaatg aaatggcaat gatgctgaag 1393321 gagcactatg ataaacagca gcaatttgtt caagatgctt cacacgaatt gaaaaccccg 1393381 ctcactatta tagaaagcta cagcagcctg atgaagcggt ggggtgcaaa aaagccggag 1393441 gtgcttgagg agtcgataga agccattcac tcagaagcgg tgcatatgaa aaaactgacc 1393501 aatcagcttt tggcgctggc caaaagccat caaggactcg aggttgatct gaaaacaatc 1393561 gatctgatta aagcggcgcg cgcggttatg caaacgctcc agtccgttta tcagcgtgac 1393621 atattgcttg aaacagataa agagagcctg cttgtaaagg cagatgaaga acgcatcaag 1393681 cagctgttga ccattttgct tgataatgca ataaagtata gtgaaaagcc tattgagatg 1393741 tcagccggaa cgaggaatgg acggccattt ctatcagtga gggatgaagg catcggaata 1393801 cctgaggagc atatcccgca tttgttcgaa cggttctacc gggcagatga ggcacgaaac 1393861 agaaaaacag gcggaacagg tttaggcctt tccattgcca agcaaatcgc tgatgagcat 1393921 ggcattgagc tgtctgtcaa aagcaagccg ggacaaggaa cagctgtcac catgcaattc 1393981 agcgaacaga atgggggagg ccgatgacta aaacaataaa aacagtatct tttgctgcag 1394041 cagccatttt agttgtcatc atctgtacgt ttctcatcat tcggcaaacc catgagaacg 1394101 tattgtcaaa ggagactgtc gtaaaaaaag tcgaagcctc ttatgaaggc aaggtcacga 1394161 aagcaacaca atcaaaggat aaaaaaacat atgatataac ccttgaaaat ccaaagggaa 1394221 cttactttgt aaaagcagac gcaatatcgg ctgacattct ttcaatgaat agagtaaaag 1394281 cagtgaatcc atctgccatg acagaaaaag aagccgagca tctcgcgctt gagcgggtgc 1394341 cgggaacggt caaaaaacaa acacggcaaa gtcaagttgc cacttatacc atacaaaaag 1394401 aagacgggaa aacatacgaa gtgaaggtag acatgcaggc aaaaacagtc ttgtctgccg 1394461 atcaaatcag cagcaaagat caacaaaaaa cgccgattac gaaaaaagaa gccaaaacaa 1394521 ttgcagagcg aaaaacgggc ggaacagcgg atgacgcaga tctcgaagaa agtgagggca 1394581 ctctcatctt tgaagtagac gttgatcttc ctgataataa ggaagcgaca gtgaaaatca 1394641 atgcctacac aggaaaggta gctaacattg tgtatgaaga ctgacggttt ctcatcaaat 1394701 tctcatcttg ctctcgtttt cctttcatgt tgagtatgta aactgtactc atacaaaaca 1394761 aaggagggct cacaaatgct caagaaaaaa tggatggtcg gtcttttagc agggtgccta 1394821 gcggccggag gattcagcta caacgcgttt gccacagaaa acaatgaaaa cagacaggct 1394881 tcttctaaga cggatgcact cactgaacaa gaagcagaag caattgctaa aacagttgtt 1394941 gacggcacag tagaagacat tgacagagac ctttacaacg gcaaagaagt ctatgaagtg 1395001 gagattgaaa aagaaggtga agactacgac gtttatgtag atattcatac aaaacaagcg 1395061 cttaatgacc cgttaaagga gaaagcagaa caagtcgcca taaccaaaga agaagctgaa 1395121 gaaattgctt taaagcaaac aggtggaacc gtaacagaaa gtaagcttga cgaagatgac 1395181 ggtgcttaca tctatgaaat ggaaatccaa acgaagcaag gaactgagac agaatttgaa 1395241 atttccgcaa aagatggacg cattatcaaa caggagatag atgactaatc aaaacccccg 1395301 ctgcagcggg ggtttttcat gataagaaac cttcttttgg acaatctaag tagaaaagga 1395361 ggcgaaacgc atggaaaaga aagaggagca atacatcaat caggctgaat atgtccctca 1395421 tccgacgaag gaaggagagt atgccttatt tcttcatgaa acgtatcatt tgctttctga 1395481 agatgacgag acacaaacaa cagaataagg gcttaggccc ttgttttgtt ccgtaattgt 1395541 gatgtaagcg catttattac ttttttgagt tgacatagct tgtttttttc tgtaatctca 1395601 gtgtgtcaat tcaattagga acttcgttag gtgaggctcc tgtatggaga tacgctgctg 1395661 cccaaaaatg tccaaagacg ccaatgggtc aacagaaatc atcgacataa ggtgattttt 1395721 aatgcagctg gatgcttgtc ctatgccata cagtgctaaa gctctacgat tgaaggcgcc 1395781 cgcacgcttt ttttgccgtg cttctttcac cttcaatccc gaaggctttt tttatgcctt 1395841 taaaacgaaa ccaatcaaag gaggtgcgga gtatggattc tccccattcg agtcaatctg 1395901 aagaagtacc catatactat gacagcaaga caattgatta cacgatgagg agacgaactg 1395961 ccgcaccttc tggcgaggcc ggcacgtctc cgtagaggag gtacgagtcc cgatggttca 1396021 aaacatgacc tatgacgaac tcattttacg catcattatt ttactgcgag acgggaaaat 1396081 cagggatttt agaagtgtta ttgatgagct tcagccctat gacatggcat ttatttttaa 1396141 agaaatgccg gaaaaacatc gcgcccgcta tttatcttat ttaactgtag acgatatcac 1396201 tgatatgatc ggggagctgg aacgcgaatt tcagcttgtc gtcttaaata aagtcggaaa 1396261 aacaaaagca acactggcga tgaacaaaat ggacaacgat gacctcgctc aattgcttga 1396321 agaaatggac gaagaactga aggaacagct tttatccagc atggaagcgt cagaatcaaa 1396381 agctgtacag ctcttgatga attacccggc tgattcagcg ggacgcatga tgacaaaccg 1396441 gtatgtgtgg atccctcagc attacacggt aaaagacgcg gtcgtcaaac tgaaaagctt 1396501 cgctgaaata gctgaatcga tcaactactt atatgttatt aatgaaagca aacagctggt 1396561 tggggttctt tcctaccgcg atttgattct gggtgaacct gaagaaaagg tgcaggattt 1396621 aatgtttacc cgcgtcatat cagcagatgc tcttcaggac caggaagaag ttgcccgcct 1396681 gatagaacgt tacgattttt tggcaatacc ggttgtagaa gaaaacaacg tgcttgtcgg 1396741 cattgtgacg gttgatgata ttatcgacgt tgttattcgg gaagctgatg aggattacga 1396801 aaaatttgcc gcttccggta aagacatcac ctttgacaca aaagcttacg tggcggcata 1396861 ccggcgtctg ccatggctga ttttactctt atttatcgga ctgatttcag gaagcattat 1396921 cagctatttt gaagacgcgc tgaagcaggt tgtcgcgctt gcgtttttca tgccgatggt 1396981 gtcagggatg acaggaaata cgggaacaca atctcttgcg gttgtcatca gaggtttgtc 1397041 taaagaagaa atgaacaaaa aaacgattgt gcgcctgatc ttccgggagt tcagaacaag 1397101 catttttatc ggagcggttt gttctgtgct gattgcgatt gtttctatca tatggcaggg 1397161 gaatgcgctt ttgggatttg ttgtcgcctc ttcactgttc ttaaccttaa tcatcggcac 1397221 gatgtcagga acgattatcc ctattatttt gcacaaactg aaagtagacc cggcgattgc 1397281 ttctggaccg ctgattacaa cgttaaacga tattttatct ttattaatct actttggcat 1397341 tgccactgca ttcattcact cattataaac gtaaaaagtc cgtctcaact gcgagccgga 1397401 cttttattat ttaacggttt ttgtaccgaa agtgagcatt aagctgcccc tccagcattt 1397461 ttttccgcac ttgcggatcg ttttttaaca tctgttcttt tttgcgcata tcctttaaaa 1397521 tctctgccgt ctgtacgccg tcttcacgct tattggcgat atccatcagc cgctccacat 1397581 cggcaaagga gtattttctt gtcccccttg aagaacgctg cgggtaaatg agctttcgtt 1397641 cctcataata cctgatctgt cttacggaca atcctgtcaa ttcactcaca attccgattg 1397701 aaatcacttt tttgtcttta taagaatgat cttctgtggt catttttcca cccctggatg 1397761 tcttttgata atagtatata aaaaacaaag agaaaaaacc tgacgcttgt catattttct 1397821 aacatcaaat agaagatttt tgaaaaaata cggaagaaaa attaacaaga ataatgcgta 1397881 acacccaagc gcgttttatc ctttatgtaa cgaatcaaac gaggaggaag gataatcatg 1397941 gaggaagaaa aagcagtctc actggcaaaa gaaattatag agttggatat caagcgtgat 1398001 gaaatgctgg agacgtttat gcagcttgcc ggagaacagg cttttcaatt attaagatcg 1398061 gttcaaaacg gacaataccg aaaatcttcg taaacataaa ttctttacat tagattcata 1398121 ccacgttcat ttaaaaagag tatcttttgt ataggatacc tcaaaatgaa ggaggacgct 1398181 atgagtaatt tattgaaatc cgctttagaa aaagaacgac gccattattc tgaaaaactc 1398241 tatcagatag gggtttataa taaagaggtc atgaacaaaa tgacgatttc tgagcttcgg 1398301 aaagaatacg cttatttctt tcgaagcatt acaaatcata aaaattatcc ttatacaaga 1398361 taatgtataa ggattttttt gcttttagaa ggaatttctc gaattatagc gaatacgtat 1398421 agtaagggac tgaactctta ttatatgtaa gggttttcat tattttttta taaaaatcct 1398481 atatacgagg tagatatgat gagattatcg tttaacgaag aagaagttga gcgtgcgatg 1398541 aatttgtaca gagtttttgc aagggctttc aaaagtgtgt ccgaacatag tatccgtgat 1398601 agcaaagagc acggttttaa tcccactgaa tttgctgtac tggaactcct gtacacaaga 1398661 ggcccgcaaa aattacagca aattgggtcg agacttctgc ttgtaagcgg aaacgtcaca 1398721 tatgttattg acaaactaga aagaaacggg tttttagtaa gggagcagga cccgaaagat 1398781 aaacgctctg tttacgcaca tttaactgac aagggaaatg agtatttgga taaaatttat 1398841 ccgattcatg cactgcgtat tgcgagagcg ttttcaggtc tttcgcctga tgaacaggac 1398901 cagctgatcg tcctgctcaa gaaagcaggc atacacagcc agcatttgct gtttcgttaa 1398961 ctattctaca ctctctattt caggagagtg tttttttgtt tccatatgat tctttttaaa 1399021 acatctttaa tcttcctatc agacatttcg ccaaggtatc cattgacgtg ttttttatac 1399081 tccttcatct gttcgttcga ttgaaaaaat gccgcgatat actcttctgc tttctgcatg 1399141 tcccagtttc tcatatctgt gacgagtttc ctttcatgta gaaggtttaa attcatttcc 1399201 tcctgtcccg gcagtgcatg ataaataaat accggaagcc gtttctgtaa gcattcactg 1399261 atggtcacgc ctccgggttt agtcatgatg cctgtcgcct gttcgtacaa acggttcatc 1399321 tctgctttgc tgtgaaggta aggaatcgcc tcaatcaagg ggtggtgtaa acttttgaca 1399381 taggagtaga gcttttcgtt tctgccgcat aatattttgt ataagatctt tccgcctggc 1399441 gacagttcct gcacccattt taaaatccca ccgaccccca tactgccccc tgtgatgatg 1399501 atggtatatg gcgggtggtg ctgcaaggta tctgctgatt ccatttcaaa attttggtga 1399561 actggaatgc cggtcaagta tatgttgttc tgatcgatac cctctgatat tagctgcttc 1399621 tttacttccg tgctcggaac aaaatggtaa tcaatgttct tccgtcccca taattgattc 1399681 acgaaaaaat cagtgtatac attcacaacc gtcagattcg gatattcagg ctttagtcgg 1399741 ttcagcagat aagaaggcag cgcatgtgtg cagaaggcga tatcaggctg tttttcttgg 1399801 aggatgtgcc tcatttgctg tgtgaacagc cattcgtaca tgaaatagcg tttgtcatgc 1399861 tgaaattctc cgcaggcgag gagcctgtaa atgccgctgt acgttttcgg gaaatattga 1399921 atccatttta aataagccac ggaggacaat ttttctaacc gcctatacga atgtgaaaag 1399981 atatcaatct tttcagctgc cagcccttga gactctaatt cagcctgcaa tgcatcagcc 1400041 acatgatgat ggccggtgga aatgcttaaa aaaggaaaaa tgagaatgtt tttcatgaca 1400101 gtcctcctaa aaaaatatgg caactatatt ttgaggagaa cgttcacaaa atataagggt 1400161 gtttttgatc ataaggaagg tgaaaagatg aaaacttgtt tcctttccat atggagagtg 1400221 gttgatccga tttatttctt tttttcaagg ctaagcttga ttgacaacga tcaaaaaagc 1400281 gtttttcgag tcaggctgac gaagtacaaa ggacatcatg tcgtgcttag cgacggaacg 1400341 catataagaa aaaatgatgt gctcgttaaa atccacctgc ataacataaa gctgatcagg 1400401 gagctgcaaa gcattgagag cgcagtcaga aagggaatca ttatttatca gaaagtatat 1400461 caatcgatgc cgcttcttct tgactatatc aacaatcata aaaaaagcga gaaaatcaaa 1400521 ggaatcattg ggattacaat gcttgacaaa ggtgtggaaa ggctcggctt tgatgtgatc 1400581 accccggtga acccttttta cagatgcttt aaaaaagtgt ctcatgtgcc gattttatat 1400641 ttgacttcaa agcctgtgag cttgcggcat ttaccgaatt catcctattt gtttatctca 1400701 aaagaaaagc tgcagaaaac ctatcaaaaa aaagactgat gcctcggtca gcacagtctt 1400761 ttttgattaa atctgatgaa atgtcacttc agggcggctt ccgacacgga tatttacgcc 1400821 ggtttgtccc aagccctcgc tgatataaaa tggtttatcg tgatgataat gaaggccttt 1400881 aatcatgttc attcgcacga gctttcccat tttcaccaaa tgatacggtt ttggccagtg 1400941 aatttgcccg ccgtgaaaat gccctgacag caggtaatca taatgaacat ctttcatatc 1401001 cagaataata tttgggtcat gtgttaagac aagatgatag ccattttcca gactttgata 1401061 agagccggtg atattactcc gattcgtact gtaatcatca atgccgataa tattgactgg 1401121 tcctgcagcc gtctcgattc gaacatgttc attttgcagc gtgatacagc cgttttcctc 1401181 taaaactcgc ttcaatctct gaaagtcctc ttctttcaat acataatcgt ggttaccgaa 1401241 caccgcgtac attccatatg caggctttag cttttgcaag gcgttcaagt aacctgccag 1401301 tttcggaata ttacgtttcc gatcaagaaa atccccggta agagcaatga tgtccacagg 1401361 ctgatctttt gttaaatgat acagctcctc aggtgagact gaaatgtttt ccaagtgaag 1401421 atcagataaa tgaaggatat ttaatttttt tctggctgga aggccgtctt tttggtcgat 1401481 tgaaatggtg ttgactttca catcttttgt attgcggttc gctttatata gaaatggcac 1401541 aaatacgagt atggccaatg aaagtaagat tgtaaacaaa atatatcccc tcccttctat 1401601 cagtatagta agtgatcaag ccctatggat agcgggaatt aatgggtaga gacaggttga 1401661 aaaacggatt gtcatatgat gaatgatttg gaagggaaaa gggataataa attttgacac 1401721 atgaggcaga acatgccgac ggagtcagaa taacaaatgg atgtgtaagc aatgttacga 1401781 ttgatgagac aacaaaaaaa agaaacatat tatctctgga tcgcattatt tcttctttta 1401841 ttgtatgtat ccccgctttt tattttaaag gaagatgccc atatccgggt ccacgataat 1401901 ttagattcca acatcgcttg gtacaaggtt ctggccgata gcggagaaat cgtcggcaag 1401961 gttgacgctg ccattccgca aatcattaac gggctgcccc gggatgcctt tggcaccgag 1402021 tggagcggaa ttgtttggct ccatgctttc ttttcttcca tgaccgccta tgcaataagc 1402081 cagacggtta caagagttgt cgcttttttt ggaatgtatg tgctgctgaa gaaacatata 1402141 atcccggaac caaaagcggc tttcatccga attggcgtat cgcttgcatt tgccttaaca 1402201 ccgttctggc cttcgggaat gctgagtacg cttgggtacc ctttggcact gtgggctttt 1402261 ttaaatatcc gaaaagggga tatctcatgg agagagtggc tgacgctggg cttgctccct 1402321 ctatactcaa gctttgttct aggcttcttc tttttcctgg cagggatggc gtgtttttgg 1402381 ctgtatgatg ccattacaaa aagaagatgg aatttgatgt tcttaggcag tattgcattt 1402441 atgacgagta tctatctttt cgttgaatat cggcttgtct attcgatgct gtttgagcac 1402501 gcaccgatgc atcgtatcga atttatctca tctaggcatg acgtttggca ttctcttcga 1402561 ctatccataa aaaactttgt ctatggccat aatcatgtga tgaccgttca taccgttgtc 1402621 atccttccga tcctgatggt cgtatttgct gctctgctgt tcaaacgaaa tcggacaaag 1402681 ccagaaaatg tttatctgtt tttatgtgtg cttaattacg ggttgtcatt atggtatgcg 1402741 ttttggttca acaaaatttg ggctgttcca aagcagaaat ttgctttttt agcagaattt 1402801 aattttgccc gttttcattt tcttcggccg cttgttatat acgtgagctt tgcgcttgct 1402861 ttatatctca tttggcggat ggggaaagga tggaaatggc ttgtgtacgc cgcagtcgct 1402921 gcacagctga tggtgttggc gccttttaat gaagaatata cgtatggtgt tcattacaac 1402981 gcgccgacat tcagggagtt ttatgcatca gagcaattca aagagattaa ggaatatatc 1403041 ggacgtccgc aagattcgta tagggtggcg agcatcggac tgcatccgtc tatcgcccaa 1403101 tataacgggt tttatacgtt agatacgtat aacaatctgt atccgctctc atataaatat 1403161 gaatttagaa aaatcatcga aaaagagctg gaaaaaaatt ctcggctgaa acaatacttt 1403221 gatgaatggg gcagccgctg ctaccttttt gtcgatgaac tcggtaaacg atatgatttc 1403281 aaaaagaact cgaagaaaac gatcaacaac cttcaattaa atacagatgt atttaaaaaa 1403341 atgggtggac ggtacatttt ttcttcagtt ccgatcatga atgctgaaca aaaccatctc 1403401 gcgctcgtaa agacgtttga ccataaagat tccgcctggc gcatttattt atatgaaaca 1403461 agataaggag gatatcgatt gaaacagtca cagccagtat taaccatcgt cgtcccgtgt 1403521 ttcaatgaag aggaagtgtt tcaagaaaca agccatcagc tgacagaggt tgtagatgat 1403581 ttaattgaag aaaaattaat tgctgaagac agtaaaattc tgtttgtcga tgatggcagc 1403641 aaagaccgca cttgggcttt gattgctatg gagagcataa gaaacaagaa ggttaccggc 1403701 ttaaaattag cctgcaatgt cggccaccaa aaagcgcttt tagccggatt gcataaagcg 1403761 aagaataggt cagactgcgt catttcgatc gatgctgatc ttcaggacga catctctgtg 1403821 atccgggatt ttatgctgaa atatcatgag ggctgcgaga tcgtttacgg tgtacgccgg 1403881 agcagaaaaa ccgatacctt tttcaagcgc acgaccgcgt tagggtttta tcgtctcatg 1403941 aataaacttg ggattaaatt aatttataat catgctgatt ttcgtttaat gaataaaagg 1404001 tcccttgaag agcttgagcg ttatccggaa gcgaatctgt ttttaagagg tattgtcccc 1404061 atgatcggct ttaaatcggc cgaagttttg tatgaccgca aggaacgctt tgccggcaaa 1404121 acgaaatatc cgctgaaaaa gatgctatcc ttcgctttta acgggattac ttcattcagt 1404181 gtcgcaccaa ttcgattctt tacgctttta gggtttgttt tgtttttcct cagcgctgtg 1404241 gcagggattg gcgcgtttat tcaaaagctg ctcggccata cgaatgcagg ctgggcgtct 1404301 cttatcatat ccatttggtt tttgggcggg ctgcaattga tgggaattgg aatcatcgga 1404361 gagtatattg gaacgatttt ttctgaagtg aaaagacggc cgaaatacgc gattgatatt 1404421 gatttgtata atgaacagct gagcccgctt cagcgccagg aaaaagagcg gttagaaaaa 1404481 aagtacagtt aaacacggaa agagctgact tcattagtca gctctttttc ttcaactgat 1404541 gcaatatagc gctaagcggt tcgtcttgcg ggttgcggta aaaatcaaaa aatgggcagc 1404601 cctgcttctt aattcgatcg atgaccgtat caattgtaaa cagagcgggt gttaaagatg 1404661 attgcacctc atgccagtag agcggggctg caacagtccc aagctcattt cctctcgttg 1404721 aatagggaca gataatcgtt tttccttctg catgctgcaa ataatcaaga tacaatttgc 1404781 agtgtctgtt tttaatcaag cgttcagtgg taaagagctc gggaaatgca ttggtgcagt 1404841 actctgcgat cagctgcgta aattggcgtg tttcttcata cgtaaatgcc tcgggagaca 1404901 agggaatata aagctggatg cctttgttgc cggacagctt cgggtacgat gtgatgccaa 1404961 aggaatccaa cagccgcttc agttcatttg cggcctgcac ggccataaga aagtcatctc 1405021 gcgaaggcgg gtctaaatca atgacaatct cagccggacg cctgctttta atggtttgaa 1405081 aaggaacgtg aaactccaaa gcaagctggt tgcaaagcca tagcaatgta gacatatcct 1405141 cacagacaat atgttcatgg cttccatcat agaaagactg aacaaaatcc ggcgcatagt 1405201 ccggcttgtt tttttggaaa aatgattcgc tcctagatcc atgcggatag cggatgacgg 1405261 tgacagcccg gtttttcaga aatgggagca ggtagtcact gacttcaatc atatactgaa 1405321 taaaatcttc ttttgttttt ttattctttt caaatatgat tttatccagg cttgtgaact 1405381 ggagctttgg gtgaaccggt ttggagtgtc gtatgacttg cgcatacgtg cattcggtcc 1405441 agtccatttg gaattcgaaa ccgataaacg atacctctct taatgtgcct tggagaattg 1405501 ttaagtattg aacagctgca caaatcgaag gttcaagcgt aaattcgcct gagggtgttt 1405561 gatgtccgtg ctgttccata atctcgcgta tagcgctttt ttcctcatca cgcattccgt 1405621 gcgagacaga ggcaatcggt gtcattattc cgttttttaa caccgatacc gtcagaaacc 1405681 cgttgttagg gttgaaccct gttatgcaaa cataagcttg tttaaagttt ttatatttga 1405741 gccaatcgga cgaccgcttc ttttcaagcc atttgctgtt tgttttcttc gctacaattc 1405801 cttctccgtc atattttatt accatctccc agagttgatc aaaatgatca taacagggaa 1405861 tggattgaat ggtttctttt gcgtaaggat ctggagatgc aggaagcttt gctgcggata 1405921 tgagttcacg cagcgatttt ttgcggtcca aatacgaaag aagcgttaca tcttctccgc 1405981 ttcgctctaa caaatcaaag gcgagaaagc agcacggccg cgcgtttgcc gattcctgaa 1406041 tcttgtctgg ccttttcaaa cgcccccgca cttgaaggtg ttcaaaatct gcacgacagg 1406101 gattcaccaa acatacgatt tcaccgtcaa gtgtcagcgg aagctctttt tctaggtgct 1406161 gaaaggcagt tttggcgaat tgtgtgattt cagggaaggt gctgctgagc tccacaccat 1406221 ttctgctggt taaggtcaca cctgaagaat ggatgcggag aatacagcgg tacccatcat 1406281 attttacttc gtaacgccat tctgctccga ttggcggtga cgaagttaag accggctgca 1406341 tggtaaacgc catgcgctat gatgtgccgg aggctttttt tctagttgtt ttttgttttt 1406401 tatctccggc tcctttcggt tcagcggctt gtgcaggtgc ggcagccggt gtctcccggt 1406461 tcggccttct ggttctgtcg atgctggctt gcagagcgct taccaggtca atgacatctt 1406521 cacgaggtgg cgctttatca ggagtgacag ccgtttcttt attttctagc ttgtcgttga 1406581 ctctttgcag cagcgcctgt cggtacgtgt cttcatattt ctcaggctca aacttagcag 1406641 tcagttcatc tattaatgtg atagcagttt gcagttcctt atcgtttaca ttcgattgat 1406701 caggtacacc tgggacttga gcggcgcttc tgacctcatc gggataatgg atagactcca 1406761 tgacgataca attttcataa acgcggagaa tcgccagctg ctgctttgac ctgattgtca 1406821 tattggcgat accgatcttt ccggttgagc gcagcgcctc acgcagcagg gtataggcct 1406881 tcgtcccatt atccccgggg ccgacaaagt aggagcggtt aaaataaatc ggatcaattt 1406941 cctgaagctg aacaaagtca acaatctcaa ctgctttctc ctcatgctcc tgttttaagc 1407001 tttttaaatc ttcgtctgtc agcactacat attttccttt tacatattca tatcccttca 1407061 caatttcatc aggactaaga gttttttcgc aatttgtgca aactttctcg tatttgattg 1407121 gtgcgtgatc ctctttatgg aggctgcgca gtttaatatc tttatcttct gtggccgcat 1407181 atagcttgat ggggatgttt actaatccga agctgatcga tcccttccac attgtatgca 1407241 tatcgataaa cccctttttt tctttagtgt gaagagaagg agtacgattc atgtgtagta 1407301 acttatgggt gaaaaaaagc cggcgctgtt attgcgacgg ctgttcaata atgaattgtt 1407361 cgaattgttc cggaggtatt ggcctgctga aaaagaagcc ctgcaaatgg tcgcagcctt 1407421 tttcaaaaag aagctgcttt tgagctgcat tttccacacc ttcggcaatc acctgcaaag 1407481 acagctgatg ccccatggca ataatagctc cggtaatttg ctctgattta ggatgggtct 1407541 gaatatcgtc aataaatgat ttgtcaatct tcagcctgtg aatcgggaag tccttcaaat 1407601 agctaagaga gctgtgacca gtaccgaaat cgtcaatact gattctgatt cctaattctg 1407661 ttagggatga caaaaccttt ttggagtgat tgagattgtc cattgtcatg ctttccgtca 1407721 cctccacttc aagaagctgc ggaggaagct ggtacttatt aagcgtatcc ttgatgaggg 1407781 gaatcagatc tttagattga aactgtctgg cggaaatatt aatggcgaca gaaagatcat 1407841 agcctttgtc atgccaaatc cttgcctgct tgcatgcttc atctataatc cactttccga 1407901 tatcaataat aagtcccgtt tcttctgcaa caccgatgaa ttctccgggc ggacgcagtt 1407961 gcccgtctgg tgtcacaagg cgtatcagtg cttctgctcc tgtcattttt tgttttttca 1408021 cactgaattg cggctgataa tgcaagacaa atctatcgtt ttcgattgct tctctgagta 1408081 ccatctcttg gttaagctta acggtttctt tgttgccgat tgaaaaagaa tagtatctgt 1408141 atttgctttt gtttcgttct ttagccgcat acatcgccat atcagccttt ttcatcaatt 1408201 caaggccatc cgtcccgtct tttggagata tcgcaatccc gatactgaca gatgtgacaa 1408261 gggtgtgatc ttgaattttg aaaggttttt tgaatttttg gataattttt cttgctaaaa 1408321 catctgcttc gcctgttcct gtattggcgt ctgttaatat aataataaat tcatcaccgc 1408381 caagacgggc gataaatccg ttatcaggga ctacagatga caggcgttta gctgcaaact 1408441 gaagcaattg atcaccgaca ttatgcccta atgcatcgtt aatcacttta aaccggttta 1408501 agtcaagaaa gaatacaaca gtgttataat gcaaggaatg ctcgcgattc agcacctttg 1408561 ttagatgaga gatggcatgc cttctgttag gtaagtctgt aagcgaatca taatgagcca 1408621 ttctatggat ttctttttct gctttgtact gcttcgtcat gtctttacaa atgacataaa 1408681 tgctgtctag ttcctgattg acctcaacag gtataagcgt aatatttaag tgaaactggc 1408741 ctttttcagt gataagatcg ctatcgctgt tcatcgcttg tttatctttt ttaacttgct 1408801 caaaaaggcg cttaaccttc agtgatgtgt aattcctcca gtcatgcatg ctgaagccaa 1408861 atttgctgat catttcctca ccagcgtgat tggaagatat tatgtctcct tctaatgata 1408921 aaataaaaat tgcatcaata ttgtggacga ttaaagactg aaatcgctgt tcgttatcct 1408981 ttatgcgttc gctctgttta ataaactttc gatctgcatg ggaactgaat aacaataacg 1409041 tttggataca aaaaataatt aaagtaacaa aaattgacca atgaaacgtt tgcacctcca 1409101 tatggcttcc gggcggagcc atgtccttat ggaaagttgc cgcaagcatc cctgtgtagt 1409161 gcatgcccga aatcccaatg cccattacaa ttgaactgac gcctttatag aatataagat 1409221 gctcagaatg tttttttacg gccaagtcaa agaatatttt taacgagacg aaagaggctg 1409281 caatcgcaat gataattgaa actgtaaata aaataggttc gtaaataatc attacccggg 1409341 aaatggcaga cattccgata tagtgcatag aagcaataga tgcgccaagc acaactgatc 1409401 cggtaagcag tctgtaatat gtaagaatgt gccggctgac aaaatataat gacacaaatg 1409461 atcccgaaac agatgcgcca atggctgcca ttaaaggcat gaattcatat tccatcggca 1409521 tttccatatg gacggccatc atccctacaa aatgcattga ccaaataccg aatcccataa 1409581 taagtgagcc gccgatcagc caaattttac tttttaagcc tgtattgatg gtgactttcc 1409641 ttgaaagttc aagggaaata tacgaggcgg tacaggcaat tagaatagat aaacatatga 1409701 gagtcgtatt atatgtaacg tgtatttcca aatggagatt ccccccgtat cgtgtgttcc 1409761 agtcttgttg actctcttta ttatcggctg cttaaccgca gagtttcagc cttcaaaacg 1409821 atagaaatac gagggagatc tatttttagt tcaactgacc gtgaaaaatg tgttaaaatc 1409881 atcttgatgt tttccgaaaa gagaaaaatg tatgatacat aaacatgaaa caagggagtt 1409941 ggtggctatc gaagagctgg ttatgtcatg gattgaagca tttaaaagct tatcttattt 1410001 tggaatattt ctagcgctca gcattgagtt tattccggcc gaagtcgtct tgccgcttgc 1410061 gggctattgg gtatctaaag gcgatatgac acttgctggc gttgttttgg caggatcgct 1410121 tggaggagtg gccggtccgc ttacgctgta ttggataggc cggtacggag gaaggccgtt 1410181 tcttgaacgt tttgggaagt atctctttat taaacctgaa gcgcttgata agtcagataa 1410241 ttttttcaaa aaacatgggg gctttgtcgc cttcagcggc cgtttcttgc ctggtatcag 1410301 gacattgatt tccataccgt gcggaattgc aaaaatgaat gtttgggtgt tttcgcttta 1410361 tacattcatt gctatgcttc cgattacatt tgtatatgtt tatctcggtg tgaagctcgg 1410421 tgaaaattgg aaggcagtcg gctctattct tgatcaatat atgcttccga tcgggatagc 1410481 gattttggcg ctgttcctgc tctacttact gatgaaaaag aggaagaaac gcacgcactc 1410541 cgaacaatta tctgtatttt tgaaaaataa acgttgacaa atcactgcgc tgcgcatatt 1410601 attgacgtat aaaatcatat ttcttgaaat cccaaagggg agtagcgtcc ggaatgtatt 1410661 ccggaaacaa agtcgtcatt tcatggattg tatccatcgg ctttgttggc atgcctgaat 1410721 tcatgtctag caagaccttt gccttatgtc ggcaaaggtc ttttttgcat ggtccggccg 1410781 gcataagatc ggatgaagag aaagaaaaca acttttttgg gagggtatca tttatggatg 1410841 cagcattatt attagagtat ggttgggttc ttctcgtctt gatcgggctg gaagggattt 1410901 tagccgccga taacgcgctg gttatggcgg taatggtaaa acatttgccg gaggaaaaaa 1410961 gaaaaaaagc gttattttat ggattggcag gggcttttgt tctgcgattt ggctctttat 1411021 ttgcaatttc tttcttggtc aacgtatggc aggttcaagc gattggcgcg atctatttgc 1411081 tgtatatctc agcaagccac ttattgaaaa gatatgtatt taagaaagaa gacacacata 1411141 aagagacgaa gcaaagcggt ttttggccga ctgttttaaa agttgaactg gcagatatcg 1411201 cgtttgctgt tgattccatc ttagcagcag tagcgctggc ggttacactt cctgggacat 1411261 cactcccgaa gatcggcgga cttgacggag gacaatttct cgtcattttg gccggcggta 1411321 tcatcggact ggtgatcatg cggtttgcgg cttccatgtt tgtgaagtta ttaaaggaac 1411381 gtccaagcct agaaacagca gcctttgtga ttgtcggctg ggtcggagtg aagcttgctt 1411441 tatatacgct tgcccatcgc gacatagcgg ttgtttctga gcactttatc cattctggaa 1411501 catggaagct gatattctgg ggtgtcttag cagcaatcgc ggtttgcggc tggtttatgt 1411561 caggtgggaa aaaacagccg gagggtgcac aaaacgaaca aaaaaacagc acccgtgaac 1411621 gggcgtaatc tgaaagactc tgcttaaaag cagagtcttt ttgtgtttga agcgttttca 1411681 taagcgaaat aaaataacat ttttataaca tctttgttac aaaaaacacg cataaaaccc 1411741 ccttaattct ttagaaaggc acgaaatcat gtatagaacg tcagaatggt ttgtcataat 1411801 tgagacattg gaaatcaata tttctttttc tcctttgcga atccctatca aattagctat 1411861 cattaatgag tagttatagg gaggaactga ggtgaaacca gtgcttagcc ttttgtttaa 1411921 attgggaaaa aagaagcaaa cacttgaaaa agctgttgag agtatacaaa aaggcaataa 1411981 agatctgcaa aatgaattaa tacagcaata taagccattt atcgcaaaga cggtttcatc 1412041 cgtttgtaaa cgatatatag atgaaaaaga cgatgagttc agtattggac tgatcgcgtt 1412101 taatgaagct atagaaaaat attcacctga aaaaggaaat tctctgctcg catttgctga 1412161 gcttattata aaaagaaaag tcattgatta cattagaaaa gaagccagaa gcgcacaaaa 1412221 tataaatatc gatttacagg aaggagacga tcaggagtca tcacaaagcc tgattgaagc 1412281 cgagctttcc attgatgaat accgccgtca gattgaacag gagcagaggc gggaggaaat 1412341 cctctatttt caaaagcagc tcaaggatta tggtttatcg tttaaagaac tgcttgaaaa 1412401 ttctccaaaa cacacggatg caaggcaaaa cgccataaag gtggcaatga cgcttgttga 1412461 acatgaagaa ttggccgcta tcctgtatac aaagaagcag cttccggtca aacagcttga 1412521 acagcttgtc tctgtaagcc gaaaaacgat tgagagaaac agaaaatata ttattgcgat 1412581 gtgtattatc attacgggtg attatattta tttaaaagat tatcttaaag gggtgctgca 1412641 ctcatgagaa gagggattat agtagagaaa aataaaaaat tcgtcacgtt gctgacccct 1412701 gacggacaat ttttaaaagc caaaaatgat cgacacagct atgaaatcgg agaagaaatc 1412761 atgcttccga gtgaaacacg catgggcaga agggccagct tttttgattt ttttaaactg 1412821 cgccctttca aaatggggat ttttacgatg actgctatta tgctctttat ttttatagtt 1412881 ctccccgttt tttctaataa taaggcctat gcgtatatga caatcgatat caatccaagc 1412941 gtcgaaatgg cgttaaacag cgattatgaa gtgattgaac tgacgcctct aaacgatgag 1413001 ggacagaaag tcgtgaatga tatagatgat tgggagaaga ctgattttaa aaaggtgatt 1413061 gacgatatta taaccgactg cagtgaacac gggtatgtaa aaaaatcgaa agaaatattg 1413121 atttccactg tttatgaaaa cacagaagac aatacatata aaaaggctgt gaaaaaacag 1413181 ctgaatgatg tgactgaaaa atataaaacg acataccgca tggaatctct cgagtcagat 1413241 atgcaaacga gggaaaaagc gaagaaagaa ggcgtctcaa caggcagcta catcaaatca 1413301 aatgaaaaga atgacaataa agatataaaa gatgactcca gcaaaccatc cggggaagag 1413361 gatcaaaaga gtgatgaaaa tgaggatgaa aacaccgatc aaactgacac ccaggacagc 1413421 aagcaaggag ataatgaaca gctgaatgat gcggattccg gagaccagaa agaagagaaa 1413481 gcggatgacc agattgatga tagtgacaaa gataaaaaaa taaaggaatc agatgaaaac 1413541 acaaataccg aaaaagatgg ggaccatgag caaaccccaa tacaagatcc tcaagataaa 1413601 ggaaatgaaa ataacggcgc tgacaagggc caaagccaat atcacaggga ctggaacaat 1413661 ggtgaacaag gcaagaaccg ttcttcgtcc agaagggata acgcttcaga ccgacgtaat 1413721 ccaaacggct acagcagtga taatcattca gctaaaaatg aagattcgcc gagtgccccc 1413781 ggcgaataaa gacctgaatt tatttagttg tgccatttaa ttgtgattgt gcttgctgta 1413841 ccagccgctt tgtcatttct ccgcctacag agccgttagc gcgtgcgact gtatcagaac 1413901 caaggttcac accgaattct tgagccactt cgagtttaaa ttggtctagt gcctgctcca 1413961 cccctggaac aacgagttta tttctgctcg ccatcttttt catctccttt ttcgataaag 1414021 aaattcttaa cgcgtattta gtttgaaata tacggggttt atttatgctg gcaattgttg 1414081 tggagaaaaa taaaaccccg gcctctgagc cggggtggcg cagactatag aatgtctgct 1414141 gtcattttat gtgcggttgc ctgaatatgg aatgtcaaaa tggagaggac tgtaatggcg 1414201 ataatctgtc tgattttaag ccattggctg tcattcagtt cttcaaaacg gtgacggaga 1414261 cgctctgtct cctgttcggc gatctcctgc agatttgatt ctttcataga aggagtatct 1414321 tggtgatgga tggcatcaag cacatatgcg cagctttcat aataagcaat cgggctgatg 1414381 acatcatcag atctgtctga gattgtgtta aaggccactt ttaaaatagc ccgtatgtgt 1414441 tcaaagtcat aaatggattt taaatcacgt acaattaaaa gaataactgc ctgttcaatt 1414501 gagtattttt tgcccagctc agggtgtccg atcagatctt tgatatcacg ctttacccag 1414561 ttttgaatcg cggttgactt taacgaagtc agctcgcata agttgccaag ctctacgatt 1414621 tcatttgtag acagaccgta ttcttttttc tgtttttttc gttcgtatct tgtaagaaat 1414681 tcaggaattt ctagatgatt ggctgctttt tctgctgaca tgttcgctga ttggacgaga 1414741 atgtcgagcg ggctatgttc tccttgtcct tttagggaat agagcagccg caccatatcg 1414801 gttcgagaga gtttaaaaat gttcattgtt cacctcttta aacaatttga cgcggatata 1414861 ggtctatgta taagttcaaa attcaagcgt cagcaaatta cattaacatc atacgtcgaa 1414921 ttccttgcat tttcaaatgg atgttttata atttaaatat acgggttctt ttgaacttaa 1414981 aataacggag gttgttatgg cgaaaagaat ttttctgttt attctaacga atattttggt 1415041 gcttacaaca atcgggatcg ttttgtctgt tttaagctct gttacaggag tcgggacgta 1415101 ctttacagct gatggcggta tcgatccaat ggcgcttctt gtgttcagtt tagtcgttgg 1415161 atttgtcggt tcctttacgt ctcttgcgat atccagatgg atggcaaaga cgatgatggg 1415221 cgtcagagtg ctgaatccga aaaaacactc gctcagctat gaggaacagc aattggttga 1415281 tcgtgttcac agattaagcc gctctgccgg tttaacgaaa atgccggaag tcgggattta 1415341 ccgttcacct gaagtaaacg cgtttgcgac tggaccgtca aaacgccgtt cacttgtcgc 1415401 agtatcgtca gggctgctgg agcagatgga tgacgcagca gttgaaggtg tgcttgccca 1415461 cgaggtcgcg catatcacaa atggtgatat ggtaacaatg acgcttttac aaggtatcgt 1415521 taataccttt gtcgtctttt tatcgcgtat cgccgcttgg atagcaagcc gttttgtcaa 1415581 agaagatcta gcgccgatcg ttcattttat tgcaatgatt atttttcaga ttgtcttttc 1415641 gatacttggc agcctggttg tgtttgcgta ttcacgccat cgtgaattcc atgctgacag 1415701 gggaggagcg gatcttgccg gcaaggacaa gatgattcat gcgctgcgga cgcttaaaag 1415761 ctattcttcc cggattttgg aagacgatca gacagctgtc caaacgttaa agattaatgg 1415821 caagaagcgc tcttcacttt tctctactca tcctgattta gatgagcgaa tcagacggct 1415881 ggaagctaaa taatacaaac acattgttcc tctgagagaa ttctcagagg ttttttattt 1415941 tatccattga ctaaaatcat aaaaaaataa gcaagttaag aaaatgtttc gtaaaagcct 1416001 ttaaaaatgg acctaatatc tttagaataa ttaccgtact taaaaagaga ggcagaagga 1416061 ttttacatga gattaaagtt tggaaaattg atacaggcct tgtcaccggc ccagctgatc 1416121 gcattatatt attttcttgc agttactgtg gccgttatat tgctgagttt gccggcggcc 1416181 cataaaccgg gggcggattg gacgtttatt gatgcgcttt ttacagctgt cagttcagtc 1416241 agtgtaacgg ggctgacagt tgttgataca gctgatacat tcagcacaat agggattttt 1416301 atattagcat ttgttctgca atttggcgga atcggaatta tgacgctcgg aacgttcatt 1416361 tggctgatca tgggaaaacg aatcgggctg aaagaacgga agctgattat ggttgatcaa 1416421 aaccaatccc agttttcagg aattgtcaat ctgatgaagc aggtactgtt tctgatcttg 1416481 tggattgaat tttttggcgg gctgatactc ggcacatatt tcttaaccta ctatgactcc 1416541 tatcaggaag cctatttaca cggatttttt gccagtatca gtgcaacgac aaacggcgga 1416601 tttgatatta ccggtaattc gatgattcca tttcgccacg attactttgt gcagtttatt 1416661 acaatgcttt taattatatt tggagcgatt ggatttcccg tgcttgttga agtaaaggat 1416721 ttcctgtttt caaagcatcg gcgttatcca tttacgcttt ttacaaagat cacgacgatt 1416781 acgttcggct cacttgtctt gtttggagcc attggcatct ttgccctgga agcaaaccat 1416841 gcgttcgcag gaaaatcatg gcatgatatt ttgtttttgt ccctgtttca atcaacggca 1416901 acccgaagcg gggggctggc aacaatcgat atcagccaat tatcagattc cacactcttt 1416961 tttatttgtg cgctgatgtt tattggagcg tcgccaagct cagtcggggg aggcataagg 1417021 acaacgactt ttgctttgaa ccttcttgcg ctgtttcatt ttgcccgcgg caataaggcc 1417081 gtaaaggtat tcaaacggga gcttcaccct gctgacttga tgaagtcgct tgttgtcacg 1417141 atgatggcga tcctgctcgt ttttggcgcg acactcattc tgaccattac agaaaaacat 1417201 tccctgctgg agcttttgtt tgaagtgtgc tcggcattcg gtacaaccgg cctatcgctt 1417261 ggaattacgg cagatttgag cagtgttgga aaatgcgtca ttatgattgt catgtttatc 1417321 gggcgaatcg gcatcttgac cttcctgtat ctgatcggaa gaaaggaaat tgaagcgaat 1417381 tatcactatc cgaaggaaag agtgattatc ggataggcaa aacaccgcat attttgcggt 1417441 gttttttgat taccaaaaaa aagatgtgtg cctcctgttc agttggagaa cctaactccg 1417501 acaggtgcaa tttacgctcc tgcatcttaa aatgtctgaa aattggcgag gaggattcgt 1417561 atgaagcgta aagctgaagt gaatgaagcc attaaaaata acaatacacc taccgagagc 1417621 atggacccca attcatataa gacacaatat catgacgacc ccaattttag aggggcaaac 1417681 cgcaattcca aacagggcca gcagggaggc atgtaattgt gaagaaaaac cgtcatagca 1417741 gagacatgca aaatcataaa aagcctatga ataaaaaggt gctggaggaa gaattctcaa 1417801 gtgaactcgg ggattacaat gccggaaaga tcatcgaaac gctggaagtc accaagcctg 1417861 aaaagaaaaa agaaaaaaac aaaaaacaac aataaaaaag acctcttagg cggcgtcccg 1417921 cttaagaggt gctttttcta ttttaaataa gcatttttgc ccgttcctct gacaaattgc 1417981 aataagcttg tcatcctcag ctcaatgaat ggctgagcga ctgtcttaac aaagttgctg 1418041 gagaggactg atgtcagggc tgctgttaaa agcaagagga tcactaagct ttgatagtca 1418101 gtaagccaat cctcaagccc gacctgccgt aatgtcttaa taataaaccc gtgaagcaga 1418161 tacacgtaaa atgtccgggt tccccatttg gtaaagaaat accgtttttg cggaacgagc 1418221 gctaaaaagc tgaaggttgc cccaaaggcg agtacatacc agccgattcg ggatagtccg 1418281 cttaccaggg taacgtctcc aaatgaagaa tacggttttg aaccaaacag aaaagaatag 1418341 tcaaaatcga tgccccagca gatgacgaat actgcggcaa gcactccgag cgcaatttgt 1418401 ttgccgcgtt ttgatctcaa taaatcaaaa tgatgtttat ttaaataaaa accgacaagg 1418461 aacatcggta agaatacgaa tgtccgtgac aagctcagcg tgctgctgac aaagtccaga 1418521 taaccgatca gcacggcgat tccgcagctg acaaacagcg cccactgctt tgaaagcttt 1418581 gaaaaaggat ataggagcag gttccaaaag aataagctta caagaaacca taacgaccat 1418641 tgcggatcaa tcgggttcac atttgccatg ctttcatctt gcataatgta ataaaagacg 1418701 gaataaataa tttggaaaat caaatacgga ataatcagct tgaccgccag cttttttaca 1418761 tatcccgccc gtttaaagcc tttcgcgaaa taaccggata caagaataaa tgcaggcata 1418821 tggaatgtgt aaatgaactt gtagaggtag agcataaaat gattatcatt aataaaggaa 1418881 cgaaggatat gaccgaatac aacaaggaat atcaataaaa attttgcgtt atcgaaataa 1418941 ctgtcccgcg atttactcat agcatcacct tctctttcat cagtcactaa gagattattc 1419001 cctgctggta catattttaa aataaaagat gaaaaaggaa tctaaaaaaa tgctgattgt 1419061 taggtcgatg taaagtgacg gtaaggatcg tagaaaatgt cttcgtaatg taatgacgct 1419121 gaaattttct gaaatttata gggcaaatga aggaagttcc cgcattttgt agaaatattg 1419181 agggataggt tttgaagaag gagtgtacat gcatggaaac tcttggtgtc cagacaaact 1419241 cggagctgcg agaggaactg aatcgcctca aagaagaaaa cgcgcgactg aaaaaggaat 1419301 tgaatcagca tcaagtgatt gtcaacaata cgctcgatgc tatttttatt tgtgataacg 1419361 aaatgcggat tgttcaggca aatgaagcaa cagaaaggat gcttcaagtt gactcggaag 1419421 atttgaaaaa gcgttctgtt ttggattttt tgttttcaat cccaaaggat gaactgaatc 1419481 tttccgtaaa gaagtttttt aaaaaaggct ttctgtggaa ggaggttccg atcaggcttg 1419541 attgcggggc aacaaaatac atagagtttc tggccaaaag aggtattggt gaggatttct 1419601 tttttgttgt catgagggac atatcttcta agaagattct ggagcgggaa ttctctatga 1419661 atgaacagct ttttaaggac ttgtttgaca gagcagttga cggaatcgtc ctgtttgata 1419721 aagatggcgg ttttattgat gcaaatttgt ccttttgtaa aagctttgaa atcaatcata 1419781 atgagctgtc tcatttatct ttgtatgagt tcatagacag cggctcacga aaagatttcg 1419841 acaatatctg gaaggcgctc aaccgcaagg gaaaagcgaa gggggagctg cctgtcaagc 1419901 ttcgttcagg agttcaaaaa ctatttgaat tcacgattac atcaaacatc atcagcggtt 1419961 tttatatgtc cattatgagg gatatcacag agaagcggtc tatggagctg cagctcttta 1420021 aaagtgagga gcgcttcaga gaaatctttg aaaatgcaat ggacgccatc atcatctggt 1420081 cgaatgacgg aagaatcgta aaagcgaatc aatcagcctg taaaattttt gagctgccga 1420141 tgaatttgct gttgaaaaga aagctgtgtg attttctcgt tgactcgcag cagaaataca 1420201 gcataacgaa gaggaaatac gcaaaatacg gagagatcag agaagagctg ctgtttcaaa 1420261 tggggaacgg ccaattcaaa gagcttgaat ttacttcaaa acggacaatc cttgaaaatc 1420321 agcatttgac gatcttaaga aatgtaagcg acagaaagcg gatggaaaag gagcttcggg 1420381 aaagcgagct gaaattcaga aaagtgttca acggatcaat ggacggcaat gtattgttcg 1420441 acaatcaata caggatcatc gacgccaacc cgttagcaag ccatattttg ggcctgtcac 1420501 atgaagagat caaacagcac agcctgttag atattatttc tgcttatgaa atagaaaatt 1420561 tggcatcacc ggcaaggcag attaattttg atgaaatgga caacgaaatt ccatttttgc 1420621 tgagcagcgg tgataacaga aaactcgaat tctcatttaa acggaatatt attcaaaata 1420681 tgaacttggc tatctttaaa gacgtaacag agcgaaaaga attggaggag cgcctgcgca 1420741 aatcagatac ccttcatgtt gtcggcgaac tcgcagccgg tattgctcat gaaatcagaa 1420801 atccgatgac tgctcttaaa ggcttcattc agcttctgaa agggagtgtc gagggagact 1420861 acgcccttta cttcaacgtg atcacctcag aactaaagcg catcgaatcc atcatcaccg 1420921 aattcttgat tttagccaag ccccaggcca ttatgtatga ggaaaaacat gttacccaaa 1420981 ttatgaggga cacgatagac cttctaaatg cgcaagccaa tctcagcaat gtacaaatgc 1421041 aacttgattt aattgacgac attcccccga tttactgtga accgaatcag ctgaaacagg 1421101 tttttatcaa tatattaaaa aacgccatcg aagtgatgcc tgacggcgga aatatttttg 1421161 taacgataaa ggcattggat caagatcatg ttctaatctc cttaaaagac gagggaatcg 1421221 gaatgacaga agataaatta aagcgacttg gtgaaccgtt ttatacgaca aaggaacggg 1421281 gaactggact tgggcttatg gtaagctata aaattattga agaacatcaa ggcgagatta 1421341 tggtagaaag tgaagaaggg aagggcaccg ttttccatat tacgcttcct gtcagacaga 1421401 atgctgaaga aagaaggaat gatgaatgaa ctactatacg acagccgaaa cgccgctcgg 1421461 tgaacttatc attgccgaag aggaggaccg gatcactcgt ctatttctca gtcaggaaga 1421521 ttgggtggat tggaaagaaa cggttcagaa tactgagcat aaggaaacac ctaatcttgc 1421581 agaagcgaaa caacagcttc aagaatattt cgcaggcgaa aggaagacat tctccctgcc 1421641 gctcagccaa aagggcactc cttttcagca aaaagtgtgg caagcgctgg agaggattcc 1421701 atatggcgaa tcccgaagct atgcggatat tgccgctgct gtcggcagtc cgaaagcggt 1421761 gcgcgctgtc gggcaggcta ataaacgtaa cgacctgccg atttttgtcc cgtgccacag 1421821 agtgatcggc aaaaacagtg cgttaacagg atacgccgga agcaaaacgg agatcaaagc 1421881 atttttgcta aacatcgagc gaatctccta taaagaaaaa taaaacatat ggcacgttcc 1421941 cttttttcac ggccgacata tcattttatt aagttaaaaa agttggtctg atgaaaaagg 1422001 aggacaaagc aattgaagcc gagccgctct gagaaacttg ccgtttttgc cgaactgttt 1422061 gtgaaactgc atatcttatc aagcgctcaa aaagatgaaa tcatcaatgt taacaaaaag 1422121 aaacaaaaaa accgctgact cggctccaaa tgagcaaagt ccagcggttt tttaatgcac 1422181 cttttctcct ttaaacagct gttcaatctc ttcttcatag tttccggtca taatcccttt 1422241 ttctgtgatg attcctgaaa tgagatcatg aggtgtaatg tcgaaagcgg gattaaagac 1422301 aggcacattg gatggagcgg tccgaactcc ggaaatctgc ctgacttcct cgggatctcg 1422361 ttcctctatc gggatatcag cgccgcattt gacctttgta tcaaatgtag ataaaggtgc 1422421 ggcgacaaaa aacggaatat caaaggcgtt tgctaaaata gcaagaccgt atgtgccgat 1422481 tttatttgcc gtatcaccgt tctttgcaat tcggtcggct ccgacgataa cagcggaaat 1422541 ttgtttttcc ttcatcgtat gggcggccat gctgtctgtg atcagagtga catcaatgcc 1422601 cccctgcatc agctcccaag cagtaaggcg tgaaccttgc aggacaggcc ttgtttcaca 1422661 ggcataaatg tgtaatccca aatctttttg tttggccaag taaaacggag ctagcgccgt 1422721 tccatagcgg cttgtcgcga ttgagccggc attgcagatc gtcatgatcc tgtcgccttt 1422781 tttgaaaagc tgcagggcgt tttggccgat caaccggcac gtttcctcat cctcgacctg 1422841 aatctgaatg gcttcatgga caaggtttgt ttttgcttca tttacggaaa tcgcgttttc 1422901 gaccgaatga ctcagtctct caagcgccca tgacaaatta atggcggtag gccgtgagct 1422961 gtttaaatat tgtttgatgt cttccagtct gcggcggaat tccgtgacat tgtctgtttc 1423021 aatgtctttg gcagcaagcg ccagtccgaa ggcagctgta atgccgatcg ccggagcgcc 1423081 ccttactttg agcgtgacaa tcgcatcaaa tacatcctct ttcgtcgtca gctccaaata 1423141 ttccgtctca tcaggaagct tttgctgatt taaaatggta atagctgttt ctttccattc 1423201 aacagaacgt ggaacagcaa atgaatgggt catgaataga tcattccttt acaagtaact 1423261 taaataattc aataacatct gttatcgttt tgaattccga acgtttttcg ataaaggctg 1423321 tgccggtttc gagcgccaag cgttttctgc cgattcgttt atcaaacggc acgatcgtat 1423381 ccaggtcagc tacatgggca aggccgatcg tgcgtcgtat cagctcacag cccgcaaatc 1423441 cgattgcttc ttcaaaaata tggctgagcg tatcagtgag gtaaccgtcg atgttggcgt 1423501 aaacatccag actgtccttc tgccaggctt cactaaacgt ctcttcaaac gtttcccaga 1423561 cctggttgac atgttcatat aacggctctc tgtcagcccc gtcacggctg agtgcgttca 1423621 aaaataagtt ggcgataaat tgccctacat caaagccgat cggtccgtaa aaagcaaact 1423681 caggatcaat cacctttgtt tcgtgctcac ttgcgaaaat gcttcctgta tgcaaatcac 1423741 catgaatcaa cgtttctgca gacgttaaaa atgacttttt cagcttagcg gcttcgattt 1423801 taacgctgtc attattccaa agcttttcga caaaaggacg aagctcttct tcaaaatcat 1423861 ttgtgtcatg gtcgaagaaa ggatctgtaa aaacaagtct ttccgtaatg tcgcatagct 1423921 ctggatttgt aaactgttta acaagctgtt ttttcacctt aggttcaagc gcgtaatctg 1423981 atgagtagaa aagtgttttt cctaaaaatt caccgatgtg ctgcgacaga tgaggatagt 1424041 tttcaccctc aatgagtcct tttcttgcga tcttgaggtg agagagatcc tccatgacgg 1424101 taaccgccat ttccgtatca gaataaaaca ctcttggaac caggtgaggc acatgctcgc 1424161 cctgacggat gagagcgctg ctttcgattc ttgcacggtc gattgtcagc ggccagcttt 1424221 ctcccaccac ttttgcatac ggaaccgcct gtttaatgat caatgctctg tcatgttctt 1424281 gatcataaat atgaaaaacg taatttaagt tgccgtctcc gatctcctgg catgtcagcg 1424341 tgcttttgct tggaaatagg ccaagcttca ccgccaacgc cacagcggag ctttcattta 1424401 acgtttcgta taaaggtgtt tttgtgactc ccatcatcat aacctccaat tatgtaatta 1424461 attaatatgt ggccgtaaaa aagcctcctt ctcagagaga aggaggctta acatctatgt 1424521 ccgcctctct tatctctcag atcagatctg aatggaatta gcaccgtgcc ttaagagacc 1424581 agcgtctcgg cgcgaaaaaa atgcgcccca tttcacaatg gaattacggt cggttgcttt 1424641 tggggtcaaa aggccaaatc cctcgcccaa ctctcgataa gagaatatat tcacttgttt 1424701 gacaattcta atttatcagt tgatgaacat ggtaacaggt aatttagtta gttgtcaata 1424761 tattttttaa tataaatctt ttctgatatc atcgaaaaca ggaatgctct cccgaacttc 1424821 tgcgctttct tgaaggtcga tttccgctcg gactatgcct tcttcccggc cgccttcagc 1424881 aagtacacgt ccccatggat caataatcag gctatgtcct gcaaattcat tatccggatt 1424941 tgaaccggta caattgcagg ctgcgacaaa gcattggttt tcaatggccc gcgcaataag 1425001 caggcttttc caatgatcaa ggcggggaag aggccattcc gcagaaataa acagcacgtt 1425061 ggcgcctttt gtcgtatgtt ttctgatcca ttccggaaaa cggatatcgt aacagatcaa 1425121 tccagagctt ttgacgccgt caagctcaaa gtatccgtct tcggaaccgg ctgataaata 1425181 cagatgctca tccatcagct gaaaaagatg ggcttttctg tactctttaa tgatttgccc 1425241 ttccttatcc gcgatgtaca ttgtattata aacatcagaa ttcttcctga cagcgaccga 1425301 tccggcgaca atatgaacac catgtttttt tgccgttttc ttcagccagc tctgagcgga 1425361 gcggccgtct tcgtcagcga gttcatcaag attggccaga tcatatccgg tcgtccataa 1425421 ttcaggcaga acaagaacat cagcatgttt gctttctttt tcgatgaaaa attcagcctt 1425481 ttttatattt tccgaaggtt ttccgtatga aatatcaaat tgaagacaag atatcgtcca 1425541 tttcatcttt ttaacacccc aaatttttct ttactttttt catttaacca tatatgatga 1425601 tggactatca tttcaagatt tttttagaag gtgagaatag atgaaatttg aacagtctca 1425661 tgtattgaag gaattgccta aacaattctt cgcttctctg gtgcagaaag tgaaccgaaa 1425721 gcttgcagaa ggacatgacg ttatcaatct gggacaggga aatccagatc agccgactcc 1425781 tgagcatatt gttgaggaga tgaaacgagc tgtcgctgat cctgagaatc ataaatattc 1425841 gtcttttcgc ggctcatacc gtctgaagtc agcggctgct gcattttaca aaagagaata 1425901 cggcattgat ctggatccgg aaaccgaagt cgctgtatta ttcggcggaa aagccggtct 1425961 agtcgagctc ccgcaatgct tgttgaatcc cggtgatacg attttagttc ccgatccggg 1426021 ttatcctgat tactggtcgg gtgtcacact tgcaaaagca aagatggaaa tgatgccgct 1426081 cgtaaaggac agagcgtttc tccctgatta cagcagcata accgctgaaa taagggaaca 1426141 ggcgaaattg atgtatttga attatccgaa taatccgact ggagctgttg ctacttccga 1426201 gttctttgaa gataccgtgc gttttgcggc tgaaaacgga atctgcgtcg ttcacgattt 1426261 tgcttacggc gctgtaggat ttgacggctg caagccttta agctttttgc agactgaagg 1426321 tgcgaaggat atcggaattg aaatttacac gctgtcaaaa acgtataata tggcaggatg 1426381 gcgggttggc tttgccgtcg gaaacgcttc ggtcattgaa gcgatcaatc tttatcaaga 1426441 ccatatgttt gtcagtcttt tcagagcgac tcaggaggct gcagcagagg cactgttagc 1426501 cgatcagacg tgtgtggcag agcaaaatgc caggtatgag agcaggagaa acgcttggat 1426561 cacggcatgc cgggaaatcg gctgggatgt aacagctccc gcaggttctt tttttgcatg 1426621 gctgcctgtg cctgaaggct atacttctga gcagttctca gatcttttgc tggaaaaagc 1426681 gaatgtggca gttgcggctg gaaacggctt cggtgaatat ggcgagggct acgtcagagt 1426741 cggactttta acaagtgaag aaagacttaa ggaagccgct tatcgaattg gcaaactgaa 1426801 cctgtttacc caaaaaagca ttgacaagac cttataacga tgggataatt caaaataatt 1426861 tataaaatct atattttctt atcaagagca ggcagaggga cgagcccgat gaagcccggc 1426921 aaccgactta taaagcacgg tgctaattct tgcagctagc ggctgagaga taagattcgg 1426981 acgagaaacg aaacctcttt agacgcgatt gcagtttgaa gaggtttttt gatatggatg 1427041 aaaatgaaag gagctctggc atgagtgagt tattagcgac atatctcctg accgaaccgg 1427101 gagccgatac agagaagaaa gcagaacaaa tcgcaacagg attgacagta ggctcctgga 1427161 ctgatctgcc ccttgtaaaa caggagcaaa tgcaaaagca caaggggcgg gtgataaaag 1427221 ttgaggagag agagggaact gctgcatcag aaaaacaagc ggtcatcaca attgcctatc 1427281 ctgaaatcaa tttctctcag gatattccgg ctttgctgac aacagtgttt ggcaagctgt 1427341 ccctggacgg aaaaatcaaa ttaatcgatc ttcacttctc tgaagcattt aagcgtgcac 1427401 tgccgggacc gaagtttggc gtatacggca tccggaagct gctgggagag tttgagagac 1427461 cgctgttaat gagcatattt aaaggcgtaa tcggaaggga cctgagtgat attaaagaac 1427521 agctccggca gcaggcgctt ggcggagttg acttgattaa agacgatgaa attttctttg 1427581 agactggtct agcgcctttt gaaacaagaa ttgcagaagg aaagcaaata ttgaaagaaa 1427641 cgtatgaaca aaccggacat aaaacgctgt atgcggtgaa tttgaccgga cgtacggctg 1427701 atctgaaaga caaagcgaga cgcgccgccg aattgggagc ggatgcgctt ttgtttaatg 1427761 tcttcgctta cggcttggac gttatgcaag gccttgcaga agatcctgaa atcccagttc 1427821 cgattatggc gcatccagca gtgagcggag cgtttacgtc ttctccgttt tacggttttt 1427881 ctcacgctct tttactcgga aaattaaacc gatattgcgg tgctgacttc agcctctttc 1427941 cgtctccata tggttcggtt gcgcttccaa gagcagatgc actggcgatt catgaagaat 1428001 gtgtgagaga ggatgctttt aaccaaacat ttgctgttcc gtcagcaggc attcatcccg 1428061 gcatggttcc gctattaatg cgtgatttcg gcatagacca cattattaac gccggaggag 1428121 gcgtacatgg acatccgaac ggtgcccaag gcggggggcg agcgttcaga gctattattg 1428181 atgcggtcct agaggcccag ccgattgatg aaaaagccga acaatgcaag gatcttaagc 1428241 ttgcgctaga taaatgggga aaggctgaag ccgtatgacg actcgaaaac cttttattat 1428301 ttgtgatttt gacggaacaa tcacgatgaa cgacaacatt ataaatatca tgaaaacatt 1428361 tgctccccca gagtggatgg cattaaaaga cggcgtactt tccaaaacgc tgtcaatcaa 1428421 ggaaggtgtc gggcggatgt tcggccttct gcccagcagt ttaaaagaag agattacaag 1428481 ttttgtattg gaagatgcaa aaatcaggga aggctttcgg gaatttgtag catttatcaa 1428541 tgagcacgag attccgtttt atgtcataag cggtggaatg gacttttttg tatatccttt 1428601 gcttgaaggc attgtggaga aagaccgcat ttattgcaac catgcttcat ttgacaatga 1428661 ctatatccat attgactggc ctcattcctg caagggcaca tgcagcaatc aatgcgggtg 1428721 ctgtaagccg tcggtcatcc atgaactttc tgaaccgaac caatatatca tcatgatcgg 1428781 tgattcggtt acagatgtgg aggcagcaaa gctgtctgac ctatgctttg caagggatta 1428841 tttattaaac gaatgccggg agcaaaacct caatcatctt ccgtatcaag atttttatga 1428901 gatcagaaag gaaattgaga atgtaaagga ggtacaggaa tggctgcaaa acaagaacgc 1428961 tggcgagagc tcgctgaagt aaaacgggaa ttggcagaga gagattggtt tccggcgact 1429021 agcggcaatc tgtcaattaa ggttacagat gagcctttaa catttctcgt cactgcaagc 1429081 ggaaaagata aacgcaaaga gacggttgaa gattttctgc tggtcgatca aaacggagag 1429141 cctgctgaaa gcgggcattc tctgaaaccg tcagcagaaa cgcttttgca tacacatttg 1429201 tacaataaaa ccaatgccgg atgctgcctg catgtccata cggtaaacaa taatgtgatt 1429261 tcagagttat acggagacca aaagaaaatc acattcaaag gccaggaaat tataaaagca 1429321 ctcggcttgt gggaagagaa cgcagaagtg accgttccga ttatagaaaa tccggcacat 1429381 atcccgacgc tagcggcact gtttgcggaa gagatttcag aagattcagg agctgttctg 1429441 atccgaaatc atggtattac ggcttggggg aaaacagcat ttgaggcaaa aagagtgctt 1429501 gaagcgtatg aatttttgtt cagctaccat ttgaaattga aaacactcga gcatcagctg 1429561 gttaaataaa aggaggaatt gaaatggcta caattcgaat tcatgatgag gcaaatacaa 1429621 cgattgaaaa tcaagaggaa gtggcaagct ttctggacag tcaagaggtt atttatgagc 1429681 aatgggatat cacgaggctt ccggaacatc tctcagagaa atatgacctg acagaagaag 1429741 aaaaacagca aattcttgat accttcgaaa ctgaaattaa agatatctca acccgccgcg 1429801 gctataaagc acaggatgtt atttcattgt cagacagcaa tccgaaactt gatgaactgc 1429861 ttgaaaactt taaaagagag catcaccata cagacgatga ggttcgtttt attgtaagcg 1429921 gacacggtat ttttgtcatt caaggccagg acggcacgtt ttttgatgtc cgtttaaacc 1429981 ctggagattt aatctccgtg cctgagaata tccgccatta cttcacgctt caggaggacc 1430041 gcaaagttgt cgcggtgaga atttttgtca caactgaagg ctgggttcct atttatgaaa 1430101 aagacagcgt gaatcaataa gcgtgagata gccccgttca tcgaacgggg ctttttatat 1430161 ttattgcaaa cgccactttt catattgtga cagttctttt ttaatcagtg tccaaatcaa 1430221 acctaaaaca gctgcatcgt caatgaatcc aagaccgagg attacgtctg gaatgatatc 1430281 gagcggcatg acgatataca ggattgcggc agttaacagc aaaagtgttt taacctgtga 1430341 acgagggtag tcgccatttc gccaatcgcg aagcatctga aaaaaagtag tgatgtgctg 1430401 gatacatttt tttcggtttt tcctctttaa aatcgctttt ccgcctgccg ctccgagcat 1430461 tattgctttc tttttcttca ttgggcatac ctcctgcctg gcggcgtgtt taagatattc 1430521 ttcacctggg tattgttctt ctaatcctat caatatatct attatacctg aaaaattaac 1430581 ttatttaatg aaaatatgtt tacaaataaa gtataatctg taataatgca caataaccca 1430641 atcaaacttg tttcctattt cttagcggcg aggggtgaag tgaatgggcg gttcttctga 1430701 acaagaaaga ttgttggtgt ctattgatga aaaaagaaag ttaatgatag atgccgctag 1430761 aaagcaggga tttacagggc atgacacgat caggcacagt caggagctgg attgtttaat 1430821 aaatgaatat catcagctta tgcaagaaaa cgaacattcc caagggattc aaggccttgt 1430881 aaagaaatta ggcttgtggc cccgcagaga tgttatgcca gcatatgatg caaataaata 1430941 gcggcctatc agatgcatat ataaagagag agcttttcgg aagcgctctt tttttctgga 1431001 aaaaattcat atgaaagagg gaactaatga aggaactggc gattctcatt accgaaatgg 1431061 tcaatcaatt tcatgatgct tttatttcct tatgcggaat atttggcatt catttaactg 1431121 acaaagaaat gcatttttgg gtgatcggca tttttggcat attctttttc ggcgtcactc 1431181 acgctgtgtt tacatggctt tctaaatgga gtatgacagc cttgtccttt atctataccg 1431241 ttacagtcat cattgtcatc gtatttgcga ttgagattca gcaaaaggtg acggggagag 1431301 ggaatatgga gtttttagat gccacggaag gtataaaggg ttttttagta ttttttatgt 1431361 tttttttgct tttgaaaatg ctgttgcgtt tcatcaaaat ccttttttct ggaagaccag 1431421 caagcaaatc gaatggcaat gcccgatcac gaagataaaa aaccctcctg acatggtcag 1431481 gggggctatg atgcggatac ggggagggtg atcgtcacct ctgtgcctct tcgcacttca 1431541 ctttcaatat gaatagagcc tccgtacatc agcacgatcc gtttacaaac aacaaggccg 1431601 agaccggttc ctttttcttt agaagtaaca aagggaagga agatgtgatc cagcatttcc 1431661 tgagaaatcc cttcaccgtt atccacaact ttgattatgg cttttttatc taaagctcct 1431721 agggagatcg tcagtttgcc tccttcaggc attgactcga ggccattttt tgctacattt 1431781 aaaatcactt gtttaatatg atcttttgta cattttacga gtaagggctg ctcggttaga 1431841 tactgtaatt cgacttcaac attgtataga ttgccctcag aataaatgat cggcataatt 1431901 tctccgataa tgtcctgaag tgagttcagc tcccattttt cagctgtcgg cttgccgaga 1431961 acgagaaact cactcactat ttgattgatg cgctttatct cctgttcgat aatggagaag 1432021 taaagctgat cttcctcacc tttatatttc ttttgcaaca gctgaataaa gccgcttatc 1432081 ccggtgaggg ggttacggat ttcatgggct gtgctggcag caagcgtccc gatcagctct 1432141 aatttttgcg cctcgttttc tgagcgctcc agctgggtct gccgcttcag caaataatac 1432201 agcacgagaa taaaaaggat attcagcaga acaataatac atgaaagcgg aagcacaagg 1432261 cttttcgaca gttcttctat tgtgaccggg ttcggataga ctttcatatt ccagctgata 1432321 tcatccagat atccgctgac aggtttctga tcctctgcat gagaggcttg tccgctcgca 1432381 aaaatcattt tcccgtcttg gttcacaact tcaatataaa catcagggct tagtaagtta 1432441 atgagatttt tcaaataatc aatttgaata gctgcgacaa gataatctgt cacattacgt 1432501 tttgagtcca aaacaggcac acaaattgtg aaaattggct gaccagtaat tctgctcgaa 1432561 taactatctg aaatgactgt ctttttagtt tcctttgctt ttataaaaaa agatctgtcg 1432621 gccaggttta ctttcgtttt taattcggtt gtgcttgcgg tgacgtctcc tttggcattg 1432681 agaaaataga gaccggaaaa tctcggctct gaatcaaagg tcttttccaa aattgattgc 1432741 attttcttta tatcaaccgg tctgtcgatg gcgatggaca aggaggtcat tctcgccatt 1432801 gtttctccga ttaaataatt gattttgttg cggtgaaggt ttagcaggac acttgcttct 1432861 tgtttatgtt ctgcagctat tgtatctttt tctttttcat atacgaaaaa gctgatgacg 1432921 attgccggaa tcacgaccag tatgatataa agtttgactc tcccgcaggc gccttttagt 1432981 attttcaatt tgcatcgctc caacatacac ctgattagag gtattatatc attgtttctt 1433041 cttctttaat aagaaaaaat aaccaaaaaa attagaaaaa gatgttggca agcttacatt 1433101 ttaaaaaaga agagaaatat tggaaagatt tttattgaca ttttggtctt tgtttattaa 1433161 tgtttctctg taacggtttc taaaaggatg attgagacat gacagaaaaa tcactgaagt 1433221 tatttatcgt gctgtcgcgc gcgtatcggt ctattaacga tcatatgaat aagcatattc 1433281 ataagcatgg gctgaatccg actgaatttg ctgtgctaga gcttttgtac cataaaggcg 1433341 atcagccgct gcagcagata ggagataaaa ttctcttggc tagcgggagc atcacatacg 1433401 ttgtagataa gctggagcaa aaagaacttc tcattcggaa agcgtctcct acagacagac 1433461 gagtgacatt tgcgcaaatt actgaaaaag gcatcggtct tttgaacgat attttccctg 1433521 atcacgctgc tgaaattgat gaaatgatca gcgtattaag cgaagaagag gtagagatgt 1433581 gcaccgaaat gttaaaaaga gtaggattaa acgcaaaaca gtttcataat aagtaaaaaa 1433641 aggaagcctg atatgtcaca aggcttcctt ttttgctatt tttcatttgt ttccgctgcg 1433701 cctctcggca aaatgagaac ttcaacccgc cggtttttgc ttcggccttc cgcagtttta 1433761 ttggaagcca ccggtttata ctcgccataa cccttggcgc tgaacacttt tgcatcgagc 1433821 ttggggtttt caatcaggag ccccataaag tttaccgctc tcatgacgct taaatgccag 1433881 tttgattgga attcagaatt tttaattggc atattatcag tatgtccgct gataatgata 1433941 tttcttggcg ggttaatcac aagaagattt gaaatctctt ttgcaagcgg cacatcttcc 1434001 ttacggatgg tcgcttttcc agaatcgaag aagatgctgt ctttaatcgt aatcagaagg 1434061 ccttcactag tcatcttcgt ctccagctga tgttccagct ttttatcttt gatgaacttt 1434121 tccacctggc tcttcacatt ttcaagttct tcttgatcag ctgctttttc tttttctttc 1434181 ttgtttttct ctttctcttc tttttccttt ttcacttcat cgatgccgtc tgactcgttt 1434241 tcaggaggag tgacactgga gtagtccagt acaccggttc cgcctgtaaa aacttcatta 1434301 aatgattttg agagcatttg aaacttagct gcgtcaatcg agctgctcgc gtacagcaca 1434361 ataaacaatg ccaggagaag agtaaggatg tcggcgtaag gaacgagcca tgattcatca 1434421 acgtgctcgt cctcatgctt cttcttcttt tttctcgcca ttttgcgcct ctccttgttc 1434481 tgcaaatttc aagcggtcct tcgcaggaag atacattaaa agcttttgtt cgatgacttt 1434541 cggtgcttgt ccttctaaaa cggataaaac accttcaatc atgacctcac gcagttttac 1434601 ttcctgtttt gattttcgtt ttaatttatt tgcgaaagga tgccataaca cataccctgt 1434661 aaagataccg agaagtgtgg caacaaaggc agcactgatg gcgtgtccaa gctcatctgt 1434721 gttatccata tgagagagag cggcaatcag cccgattaca gcgccgagta ctccaagtgt 1434781 cggagcgtac gttcctgctt gtgtaaaaat agcggctcct gcttggtgcc tgtcctccat 1434841 tgcttcgact tcctctgtca taatatctct tataaattcc gcgctttgcc cgtcaacagc 1434901 catgctgagc ccgtttttca agaaagcatc atctacatcc tcaatgcttg cttctaaagc 1434961 aagcagacct tcgcggcgtg caagctgagc ccattcagag aacataggaa tgagttcctc 1435021 tattgtgagc tgtttatttt ccttaaataa cactcgaaac agcgtaggca cttttttaat 1435081 ttcttttgtt gggaacgcaa taacgactgc tgagattgtc ccggcgataa taattaaaat 1435141 ggcagcgggg tttgcaaggg cgctgaaact gacgcctttc agaaccatcc cgacgctcaa 1435201 tgccacaaaa gcaagaataa taccgattaa cgaagtttta tccatagttt tcaccaaatc 1435261 cttttttact agcttgtcta tggttaatat cggttttggt gcccggaact ttagggacat 1435321 tgtgaatttg ttcatgaaat attcaaggaa gaggcataga agggagaaat aaacaaaaac 1435381 gggctctcca aaattgaaaa gcccgggggt ctactgaaat tagcagcttg cttgcaagct 1435441 gtccttcaga tggtattcat ataatagtag aaatacatat tcactgtata taaacatgtt 1435501 ccatccctcc ttaaaaaagt gtaaaggatg aagggaagta gcgcttcagg agaagggacg 1435561 gtaatttcta agtcaagagt atgaaagtat aaaaaaaagc ggcttcctaa aaggaaaccg 1435621 ctgattgtta ttttgctcgc actttgattt tatcatcttc taaaatcacg tgaaaacttg 1435681 tgatctcgcc attatcaagc agcagatcgg tcatttcatc ctcaacccat tcttggatgg 1435741 ttcttctaag cggacgtgca ccgaatgaag ggtggtagcc cagctcagcg attttttctt 1435801 tcgcttcatc tgtcacattc aagctaatgc cccgttccgc caatgtttct tcaagttctc 1435861 caagaagaag gctgacgatt ttgacaagat gttctttttc caatgagcgg aactcaataa 1435921 tgctgtcaaa acggttgagg aactcaggtt taaagaacat gctcagtgaa tcaattaatg 1435981 tttgttcttc gatgacactg tcatctgatt ggaaaccgac tttcgtttgt ttctcaccag 1436041 cacccgcatt acttgtcatg atgatcacag tgtctttgaa gcttacagtt ctgccttggc 1436101 tgtctgtcag acggccatct tccataattt gcaggaacat atgctgaacg tctgggtgtg 1436161 ctttttcaat ctcatccagc aacacaatgc tgtaaggatt gcggcgcacc ttctcagtta 1436221 attgtccagc ttcctcatgg ccgacatatc caggcggtga accgataatt ttagatacgg 1436281 cgtgtttctc catgtattcg ctcatatcga gtcggataat agcgtctttt gtgccgaata 1436341 attcatctgc cagtgtttta gaaagctctg ttttccctac gccggtagga ccgacgaaga 1436401 ggaaggagcc gactggtctg tttttggatt ttaatccggc gcggcttcgt cttaccgctt 1436461 ttgccacttt ttgaacagcg gcttcttgtc cgatcacgcg ttcatgaagt tttgcttcga 1436521 gttctttcat tttcgtttgt tcgtctgcct gcagtttgcc gacagggatg cctgtttttt 1436581 gttcaacaat ttcctgaatg tgctcagctt ccacagtgac agcggtatga gcggaggagc 1436641 tgttcagttt tttctccaat gcgagttctt catcacggag ttttgccgcc agttcgtaat 1436701 tttcttcttc cagggctttt gttttttcgg cttcaattgc agttaagcgt tcagcggcat 1436761 cctcatcatt cagttcatca attaacaggt tggcttttga acctgcttca tctaataaat 1436821 caattgcttt atccggcagg tgtctgtcct gaatgtagcg ggatgataaa gtgacacatg 1436881 ctttgattgc ttcatcactg aatgttacgc catggtacgc ctcgtatttg tctttaatcc 1436941 cttgcagaat gaggatagcc tgttcaattg aaggctcctg caccatgaca ggctgaaaac 1437001 gtctttccag cgcggcatct ttttcgattt gacgatattc tttcagtgtt gtcgcgccaa 1437061 tgacttgcag ttcgcctctg gctagggccg gtttgagaat gttgccggcg tccattgatc 1437121 cttctgcaga gcctgcgccg acgagaaggt gaatttcatc aatgaacaga atgacatttt 1437181 ttcgttcctt cagctcagtg atcagctgtt tcattctctc ctcaaattgg cctctgatcc 1437241 ctgtgtttgc aacaagagat gcaacatcaa gcaagtatag ctctttgttt tttagtttgt 1437301 ttggaacatc accttcagca atttttaaag cgagcccttc agcgatggca gttttcccta 1437361 cacccggctc accaataaga accggattgt ttttgtttcg gcggtttaga atttcgatca 1437421 ctcgcgccac ttcatcatca cggccgatga cgggatcaat gagaccggct tttgcaccgt 1437481 ttgtaatatt ttgagccagc tcatcaagca accctttttt ttcgctttgt tttgctgcgc 1437541 tctgttcttt cggctggaat gcctgttcaa acggaaatcc gaaagattga ggacccatac 1437601 tcattgaagg tttacgggtc agttcgttat agcaagtttc acaaagaacc atctgtttat 1437661 gaacggaatt tatttgcatg ttaaggcgaa tcgtcgcctc gttttgatga caatgttgac 1437721 aacgcatttg ccaaaacctc cttaataatt tgatcatctt tgaccaatga aagtgaataa 1437781 aaaggtctat tgggtttgac cttctttgac tattagtata cggcaaactt aacggcattc 1437841 aaaccaatat gctcaaagca gactgaatat ttgactatct ttgaccaatt gatttttaaa 1437901 aaaggccggt ttgtttgacc aactttgatt aatagtatac tctgactatc tttgactttc 1437961 aagtcttatg cacaaaaatt tttgatttgt tacaaagtaa aacatgtttt cttcgtcttt 1438021 tcaaggaact tgtctcatag gttataaaaa ggcatatatg gacaaaactg cggttcgttc 1438081 ggagggaaga aatggaacaa tcaaaagggt ctgcaagtca gcttgctttt gtgtatgtcg 1438141 gcacagtagt cggagctgga tttgcgactg ggagggaaat tgttgagttt tttctgaagt 1438201 tcggctggtt cggttttttc ggcattctcg tcagcggcgg aatgtttacg ttactggggg 1438261 ccaagctgat gatcatttca aagcgaatca atgccaagtc atatcaagaa atgaacatat 1438321 ttttgttcgg ggcgacggct gggcggatta tcaatgtatt tatgctgttt gttctccttg 1438381 gagttacatc tgttatgctt tcaggggcag gggcgctttt tgaggaacag ctggggatgt 1438441 ccgctcagat tgggatgctc attacaatcg gtctgagttt aattgtgatg actagaggag 1438501 taaaaggcat tttcggtgtc aatgtgtttg ttgttcctct tttaatcatc ttttcaatga 1438561 ttgtggtggc cgactctttt atattcagcg aatcacgaaa cgcagctcag tgggtctggc 1438621 cgcatcgctg ggattggctg ttatcagcag tttcttacgg ggctttaaat ttatcgcttg 1438681 cccaagctgt tttggttccg ctggcgaatg aaatgtcatc ggagaaagtg ataaaaaaag 1438741 gcgctttaat cggaggcacg atgctgacga ttgtgctgtc cgcgagtttt ctgtctttgt 1438801 cgactcttcc ggatgtattt ttgtatgata taccgatggc gcaagtggtt tatctctttg 1438861 cacgatctgt ccatttgatt tatttactca ttattttcgg agaagtgttc acatcagtta 1438921 tcggtaatct atatggatta gaaaaacaag tgcaaagctt tcttccagtg aaaagcaaat 1438981 atatctttgc agccattatg atcacggctt atattacgag ccaaataggg tacggcaggc 1439041 ttatttcaac gatttatccc ttgtttggct atgtgagcct ggccttcata ggcgctttgc 1439101 tttgcaaaaa agctcctcgg cggcgcagtt tataaatata tataatgaaa cgaaccgtca 1439161 ctatagagcg ataattgatc taggaaccgg ggactgactt ttttattgtc aagaaaaaca 1439221 tcattatggt aagatagcag aagtgaaaaa attgaagaaa atccgtgcga tatgcgggag 1439281 aggttctagc tacaccctct ataaaaaact aaggacgagc tgtatccttg gatacggcct 1439341 tttttatgtt tttctagagc accttccgaa aaaaggtgtt tttttgcgtg aattagctgt 1439401 agcgatgtct ctcgccggcg tttttattgc ggagaaggag aggaatcatg aaaaaagaaa 1439461 aagcaattgt cgtatttagc ggcggtcaag acagcacaac atgcttactg tgggccttaa 1439521 aagaattcga agaagtcgaa acggtgactt ttcattataa tcagcgacat tcgcaggaag 1439581 ttgaagtggc aaaatccatt gcggaaaagc ttggtgtgaa aaatcatttg cttgatatgt 1439641 cacttttaaa tcagcttgca ccgaatgccc tgactagaaa tgatattgag atagaagtaa 1439701 aagacggcga actgccatcc acattcgttc caggccgcaa tttggtattc ttatcctttg 1439761 cgtctatcct ggcttaccaa attggcgcgc gccacattat tacaggagtt tgcgagacag 1439821 acttcagtgg ttatcctgac tgccgtgacg aattcgtgaa atcttgcaat gtcacggtaa 1439881 atctggcaat ggagaagccg tttgtgatcc acacgcctct catgtggctc aataaggcgg 1439941 aaacgtggaa gcttgcagat gagcttggcg cgctggattt tgtgaaaaac aacacgctga 1440001 catgctataa cggcatcatc gcagacggct gcggcgaatg tccggcatgt caccttcgtt 1440061 caaaaggtta tgaagaatat atggtgatga aaggagagcg tgcataaatt gttatctcaa 1440121 atttatccgc aggcccagca tccttattcg tttgaactga ataaggacat gcatatctca 1440181 gccgctcatt ttatccctcg ggaaagtgcg ggagcgtgca gcagggttca cgggcatacg 1440241 tataccgtaa atataaccgt tgccggcgac gaacttgacg attcaggctt tcttgtcaat 1440301 ttcagcgtac tcaaaaaact ggtgcacgga aactatgatc acacgctatt aaatgatcat 1440361 gaagattttt ctcaggacga ccggtattcg ctgccgacaa ctgaagtcgt ggcgaaaacg 1440421 atttatgaca acgtacaggc ttatttagac actttggaga ataagccgac ctgtgtacag 1440481 gtgtttgtcc gtgaaacacc gacaagctac tgtgtctacc gtccgaaaaa gggtggtttg 1440541 aatggctaaa ggaattcctg tattagaaat tttcggcccg acgattcaag gagaaggcat 1440601 ggtgatcgga cagaaaacga tgttcgtccg gacagccggc tgcgattatt cctgcagctg 1440661 gtgtgactcc gctttcactt gggacgggtc tgctaaaaaa gatattcgct ggatgacggc 1440721 ggaggagatt tttgcggagc ttaaggacat tgggggagat gcgttttctc atgtgacgat 1440781 ctcaggcggc aacccggctc tgttaaaaca gctggatgct tttattgaac tgctgaagga 1440841 aaataacatc cgtgcagcgc ttgaaactca agggaccgtt tatcaggatt ggtttacgct 1440901 gattgatgac ctgacaattt ctccaaaacc gccaagctca aaaatggtaa cgaactttca 1440961 aaagcttgac cacattttaa cttcacttca agagaatgat agacagcatg ctgtcagctt 1441021 gaaggttgtc atctttaatg atgaagatct ggaatttgcc aaaactgtgc acaagcggta 1441081 tccgggaatc ccgttttatt tacaagtcgg aaatgatgac gtgcatacga cagatgatca 1441141 gtcactgatt gcacatttgc ttggaaaata tgaagcgctt gttgataagg tagctgtcga 1441201 tgcggagctg aatctcgtca gagtgctccc gcagctgcac accctgttat ggggcaacaa 1441261 acgcggagta taatagaaag gaagatgaac atgacgacaa gaaaagaatc agaattagaa 1441321 ggtgtaacat tgctaggcaa tcaaggtaca aattatttgt tcgaatatgc accggacgtg 1441381 ctggaatcct tccctaataa acatgtaaac cgtgattact ttgtaaaatt caattgcccg 1441441 gaattcacat ctttatgtcc taaaacaggc cagcctgact ttgcgacaat ctacatcagc 1441501 tacattcctg atgaaaaaat ggttgaaagc aaatcattaa agctgtatct attcagcttc 1441561 agaaaccatg gtgacttcca cgaggactgc atgaatatca tcatgaacga cttgattgaa 1441621 ttaatggacc cgcgctacat tgaagtatgg ggcaaattca cgccaagagg cggaatttcc 1441681 attgatccgt acacaaacta cggaaagcct ggcacgaagt atgagaaaat ggccgaatac 1441741 cgtatgatga accatgattt gtatccggag acaattgata atcgttaatt attccgttgt 1441801 gtgatacgga gtgtaaaagg aagtggagtc acagtaaaat ccgaacattc agcgttaatt 1441861 ttcagcggaa atgtgacctg gtcacagcga agtgtgaccc gcactaagct caataaaagt 1441921 gggaaaagtc acacctgaaa atggctctac tcatgggaat tgtattaaaa agtgtgacct 1441981 gaggtgcaac ctgaactgtg acttttatgc agtgaaaaat tgatagtaca gaagcagatt 1442041 aaggcgtaca atttgtacgt cttttctttt ttatccgaaa gaaaaaatgc ctatctagag 1442101 atcataggca ttaaatatta ttatcaatat cttcatttat tttttggcta agtttctgaa 1442161 ccttctcttt aacatttgaa acagctcttt tttgaatttc atcaattctc ctgaatatag 1442221 tcgatgacac ttcttattag aacttcactt tcaaaattga atatctcatt tatttctgac 1442281 tgttcttcat ctgttaggtg atggtattga agttgtttag catttacttc agcagctaca 1442341 tcaatcctaa cttagttgtt ctggttgtac aatttcatat tcaccttctg catactcttg 1442401 ctccgcataa tagcctcccc attgacagag ctcctgcaag ataggtttaa gagattctcc 1442461 aagttcagtg gatgaatatt caaccttcgg cggtacttga ttatacatct ttctgctcac 1442521 aagtccactg gcttcaagct ctctaagtgt ttgaatcagc attttctgag ttatatttgg 1442581 gataatgcgc tttaattcac tcgttctctt tggtccattc attaaaaagt ataatacaag 1442641 gcctttccat tttccgccaa taacttcctt tgtcacttca aacccacagc taaatttttt 1442701 catgtctaaa gctctccatt ccacatttat tactttttag ttactatatc acaaaaaagt 1442761 gggtacttcc gataatgtgc ttactgaagg atactatatc ttgtaagttg ttcttcaagt 1442821 acttaaaggt actagacata aaataaaatt aattctaaag gagtgttaag tatgggtaaa 1442881 tttgaaggta aaatagcgct tgtaacgggt ggaacaagtg ggattggtct tgctacagca 1442941 caaaaatttg taaacgaagg tgcatatgtt tatattacgg gacgtagaca aaacgaactt 1443001 gataaagctg ttaaccaaat tggcaagaac gtaaccggtg ttcaaggtga tatttctaag 1443061 cttgaagact tagacaaact atatgacatt ataaagcagg aaaaaggtaa gttggacatt 1443121 ctttttgcta atgcaggcat cggcaacttc cttccattag gtgaaattac tgaagagcag 1443181 gttgatagaa cgttcgacat taacgttaaa ggaaccatct ttactgttca aaaagcgtta 1443241 tcactattcc cggacaaagt aggttctatt attgtaacgg gctctactgc tggatcaatt 1443301 ggcaacccag cgtttagtgt atatggagca tctaaagcag cattaagagc actagttcgc 1443361 aactggattc ttgacctaaa aggtactgaa atccgtgtaa atgtggttag tccaggaggt 1443421 attcttacac ctgcctacga tgagcttttt ggtgatgcac ttgaagaggt actggaaaat 1443481 agcagaaata ctgttccagc tggaaaagtt gggacacctg aagaagtagc aaacgctgta 1443541 tctttccttg cttcagacga aagcagttac ttgacgggtg ttgaattgtt cgtagatggc 1443601 gggctagcac aggtataatt tcactgcgca gagattacaa atagtcccca aaaaaggtta 1443661 atggggattt acttgaagaa gtcgtataaa aaagtcgttt tccttaaagg acagggaatt 1443721 cgactttttt atatttgaat ttgattaacg ttgtaaattc gcattttcct ggggctacta 1443781 ctaaatgacc tgtaaaaaag attacactgt gaataaatgt acttaaagta acgggggctc 1443841 ttgactttta ataaaaaata atatccctgt ccttgtattc taatactttt aaaaatattt 1443901 aaaggaatcc ttatgtcctg aataaccaca taggaaaata tgttgtaggt tgctttcttt 1443961 ttttgtgggg catcccacac aagctatctc gtgatctcac acctgaacgt tttttataga 1444021 ctagtaccgc gacaagttat attacatata cataccaata aagtagacat taaaaagtga 1444081 aagagaggat ggaaatgtgt gaaaattctt ttccttgaga gtcatcccat gtggctctat 1444141 ggtttaccga atgggtttag ggaagcagga cataccgtaa tgatttccgg tcctgtaagt 1444201 cgggaaaata taactgaaat gatagacgaa tttaaaccag atttaatagt atctatggga 1444261 tggacaccag agcattcaag ggaaaagcag gcctggattc gcaacgctac taaaaaggtg 1444321 aatatccctc tcgtttattg ggcaactgaa gacccgctgc acactcaaaa ctttactatc 1444381 ccgttaatta aaaagatgaa accggatttt gttttcacgg tcacgccttc tctgtgtaaa 1444441 acttatgaaa gcatggggat taaagcagct cacttagact ttgcatttca cgaaagtata 1444501 catcaccaga ttaaaccatt agcgaaatac agttgtgata tagcagtggt ggctaatgct 1444561 taccctaatt ttcttgaaga acatccggaa gtgttccgtt cgtcctcttt aaaaacgctt 1444621 attcgtcctc ttatacggaa gggtattcgc attgattttt gggggagaaa ctgggaaaaa 1444681 atgagtaaat atataggaag agaaattccc cgcaattgga tccatggata ccttgattat 1444741 actgaagcat ataaagttta cagttcagca aaaatcatta tcggtttgca aaactgtgaa 1444801 agccaactta cacaacgcac ctatgagatt cttggttccg gggggttttt attgacatcg 1444861 gatacaccag cagttcgagg taaattcaaa cctggccgcg atctcatcgt ttcttcctcc 1444921 ccaaaagaaa cattggaaaa ggttaaatac tatttaaatc atgatagcga gagaaaaaag 1444981 attcagataa acggtaaaaa ggctgtaaag aatgattcct atcggcatag agccgagaga 1445041 atgcttgagg tgctaaaaag cagaggaatc ataagaaact taggggaaac cattcattat 1445101 gtagatgttc tcaaagaaaa atacgtgatc catcatgtta ctcccggtga aacattatca 1445161 ataattgcca gtaagtataa tgtttccctg cagcaactca tggagcttaa tcatttcaaa 1445221 tcagatcaaa tatatgctgg acaaatcatt aagattagag agaaactgtt tagaaatatt 1445281 aataacaaat tattctaaag gagagtaata tgaatgaagg ggaaaatacc taaaataaga 1445341 aatcaagcga ataaagtaaa aagaacgcct cgttatatgg aatttcccgt gacatacgaa 1445401 gtatatcatg tggaatccgg cgatacatta tggacgattg ccaaatcctt tgaaattccg 1445461 gtacaacaac ttatgaatct taataagctt tcttcagata gaatttatcc tggacaaatt 1445521 ataaagataa gagaaagata atctttgagg tttcggaagc gaatcaaatt gaaatgacaa 1445581 tcctcatttt tttatttgtg gggaacttga tatttttggg gatgaagggg ttatgagatg 1445641 tttcaaatga gctattacta ttctggatta ggatgggact ttattcaaca cgttgatcaa 1445701 acgaacggag tattaaatgt tgtgtctcct gattttttct atatcagaaa agatggatca 1445761 ttacttctcc gttcagctaa tcccgatgtg attaaagctc ttcatagaag aaaattaaaa 1445821 gtagttcctt ttctaagcaa tcattgggat caggatttgg gacgatttgc attaatgaac 1445881 cgagttcttt tagctaaaca aatttctcat gcaatagaag aactggattt ggatggagtt 1445941 aatatcgata tagaaaacct tacagaaaaa gatcggaatc tatttacaga ttttattaga 1446001 ttagtaagga aaagtattcc tagacataaa gaagtatcag ttgcagtggc ggcaaatcct 1446061 tttggctgga cgaagggctg gcacggatca tatgattacg agtatttagc taaatatgca 1446121 gattatctta tggttatggc ctatgatgaa agccgccttg ctgggcctac tgcaagtgta 1446181 ggatgggtgg aaaagtccat tcaatatgtt ctgacccaaa aaatctctcc tcaaaaacta 1446241 gttttaggat tgccattcta tggccgctgc tggatggaag gccaatctgc ctctcaagcc 1446301 attccccttt accttgttgt tagtaaaaag gcatagcggg acaattattt ttgacaccaa 1446361 gagtcaatct ccaaaagcta tttttactgt caatcacgat aaaaaggggc cgttgccttc 1446421 gggaacatat acattatggt ttgaaaatga acagtcactc agagcaaaaa taaaactcgc 1446481 tcaaaaatat aatctgaaag gtcttggcag ctggagtctt ggacaagaag atgcgtcagt 1446541 ctggaataca gtgtttaaaa atatataatg atttatagtt cagaacaaaa ttcgaagata 1446601 attgcaatga atctctaaat ggacatactg aaaggagttt attacgagtg cgggtaaaac 1446661 agtgagggca ttccataggc ccttctccca aaatgttcta cacgaggcat tacattgggc 1446721 ttgaaataca cattcaaact tatgttatag tacgcatttt acggatgtgt tgaatttatt 1446781 ctgcttccat gatttaatca tacacatgct acttgatagc agggttatcg catttcattc 1446841 agaattgttc aggatcgata tggaagcgca cgactaacta gaactttaaa agcatacact 1446901 catatacttc ctgaatggat gctggtttat ctaaaaaaca tgatgagaat tgattgtacg 1446961 catggtgaag catgacttgt tgataatcga ccatatggtt tctccttaga aatgaggggg 1447021 tttttacata aaaaagacga gcgaatccgg ggggaattcc actcgccgct ttctaatgaa 1447081 aagacgggat gctggatggc agctcgtctg ttttattata atttaacgaa cgtatgtttg 1447141 taaaggtgtc ttttcgaatg aattggttca tataaccgtt aagaacagat tcattgtaaa 1447201 cattcgctaa ggtatgctaa gatgcatgga ctataaagga gtgatatgaa gtgaagacat 1447261 tgcggttaaa caatgtaacg ttagaaatgg ctgcatatca agaggagagc gagccgaagc 1447321 gaaaaattgc atttacctta aacgttacga gtgagactta ccatgatatc gctgtcctgt 1447381 tgtatgaaaa aacgtttaat gtcgaggttc cggaacgcga tcttgccttc cggggggaaa 1447441 tgacaaatta ttcaacatca ttgaccaacc tgtacgaacc aggggccgtc agcgagttct 1447501 atatagaaat aacggaaata gacaaaaacg ccgattcatg atcggtgttt tttatgtaaa 1447561 aaagctgccg gccggcagct tttgagaaag cgaatttcat atgtaaggtg ttaaattgtc 1447621 cgtcttgcag ttttttgaat aaatgtggaa ataaggaggt tttaatagga gtctctgatg 1447681 atcttataat ttttatgatt aacaactgtc aatgaatcta actcaagatc ccgatagtta 1447741 tccatgatcg tcacatcaac gataacagaa ttctcattta ctttttcaac aacaccggtt 1447801 aatccgtttt taaattcaat gacattccca accttagcga ttttcacaag cttcctctcc 1447861 tttaaacata ataatgcctt ttgaaagtat tttgcagtat tttcattgag aagtaaagcg 1447921 ataaggagtt ttatctccct tatgaattgt tctgtcgcta taaagatgat atattgattt 1447981 tcgtcaatag aaagaaaagg ggggaatttt tgttgcgtcc cgaagaaata acagaaatga 1448041 ttgaacagct gcgcaccggc gccataaacg aactgagagt ccagaaagag cattttcttg 1448101 atttcagggc cgtgttatct aaacaagatg attttaaaca tttccgagga attgcccagc 1448161 aaggcggaga tgttatcttt caatacttag aacagccaag aagctgaagg tttctcatac 1448221 gtgagaagcc tttttatcat atatgacaga acacaagcct tttattacag ctgtctgtaa 1448281 caggtgtaaa taaaatgtaa agtaccaaag atggataaac atgttttaat ttaacaatat 1448341 ttatagaatt tcagactgtt tttttgccat taagcagtga gtcatcctct ttattccatc 1448401 ctgatacctc cttgggagag ttggaaaatc tttttccgtg aaaatgaatg gatctcttgt 1448461 taaggttatg aagtgttttt tggagcactt taaggaggaa actgtatgac aacgaaattc 1448521 actgctctgg ctgtttttct tctttgtttc atgcctgcag ccaaaattga gcatacacaa 1448581 gcttcactac tgagcgcaaa gaagacaaaa catgaagaag cgaaatggct tacacatata 1448641 gatcgaaata cgaatgaatc tttcccttca ctgtctgctg ataaagacaa gaaaataaaa 1448701 ccgattaagc tatcagcaca cactgaaaag aaagagaaag ataaaccgga caaaacaaat 1448761 gatgagaaag aaacatatac acagtctgaa aaagagttgc tgtcccgtct cgttcacgca 1448821 gaggccaaag gagaatcata taaaggcaag gtcgctgtag caagcgttgt actgaacagg 1448881 acggagaaaa aaggttttcc tgatacgata agaggagtta tttatcagaa aaacgccttt 1448941 gaaccggtcg caaacgggag cattaaccaa aagcctgata aagaatcgat tgaagctgcc 1449001 gaagaagcgc tgtcctcaaa aaatagagaa acagatgcca tattctttta taatccgaaa 1449061 acagcgtcag ataattggat tcgttcaaga aaaatcgtag aaaaaatcgg cagacacgtt 1449121 tttgccgtct aagcatagaa gagacaattt gtctcagctg tgcttttttt catataaaga 1449181 gtaaaaataa aataattttt gaacttgtct catatgatgt tggtagtaca agagacaagg 1449241 agagacatca tgaatcgatt tgtgaaaggg atcattcttt tatccattgc cgcctttttc 1449301 gctgaatgcc ttgaatttgt cgtcaatatg attttggcgc gggagcttgg cgagcatggg 1449361 atggggcttt acatgagtat tttgcccacg atctttttaa ttattgtcat cgcgagcctg 1449421 gaactgccga tatccatttc taaattcatt gccgagtcaa atcctaagct tcatgaaagc 1449481 atgctgaggc acgctttcag aatgacagcc atttttactg ctttttctac tgccgccgct 1449541 agtattgcgc ttccgtttat tccggtattt gatacatacc acccgtttat taaagggatt 1449601 gtcatcggct taattcctgt tgtcgccttt acttcaatcg ccaggggcta ctttatgggt 1449661 gtgcagaaaa tggggaagat cgcaattgcc aatgtgctga aaaaaatcat ccagctcttg 1449721 tgcttattcc tcttttttca atggtactca tttgaattgg acatggctgt gctgatttcc 1449781 ttgtttgttc tagtcgtgag tgatgtggtc gtgcttgttt atttatattc acaatttatc 1449841 atggcaaggc gggcgttatc cggccagcag cacattcatt tgcgcggaaa ggatgtaagg 1449901 aaaagactgc ttgctgtttc aattcctaca acaggactgc gtatttttca tgcggttgtc 1449961 aatgcaattg aacccttttt agtaaaagga gctcttttgg ctgcgggcgt tgccgggaca 1450021 gcggcgatcg atcaatacgg aatgctggca ggagtggctg tgacgatagg gtcgttccct 1450081 gcttttattg cccattcgtt aatggtcgtc atgataccga gtatttcgga agcttatgca 1450141 ctttctcagt atgacatcgt gttaaaaagg ctgaagcagt cgattttcat tacattaggt 1450201 tacggtatac ctgccgtctg ggtcatgttc cagtttgcgg gacctctcac gcatttgttt 1450261 tttcactctc ctgaagcgca gtattacttg cagctgttgt ggccttactt tctctttcat 1450321 ctgtttgtca tgccgctgca ggcgtgctta atcgggatgg gttttgtgaa agaggctttt 1450381 tatcacaatg tatggagcca tatcgttgcg ctaagtatga tgtatgtact gggatcaatg 1450441 gagaatctgc aaatgctcgg gattatcctt ggaatgaaca ctggcatgat tcttttgacg 1450501 agcctgcact atgccacgat ctgcaaagca ttgaaggtat ctgtatttct tacgggaggg 1450561 accagaacgc cgcgaattga aggatgataa aggaacagca ggggcaagct aattgaaaag 1450621 catgaaagga agattccatg ttgacgaagc gcttgcttac tatatacatt atgttattag 1450681 ggttgattgc atggtttcca ggtgcggcac aagctgagga aaaacagcct gctgttcccg 1450741 ctgtttttct tatgaaaacg atagaagggg aggacatctc gattccgaat aaagggcaaa 1450801 aaacaattct ccatttttgg acgtcatggt gcccgccctg caaaaaggag cttccacagt 1450861 ttcaatcgtt ttatgatgcc catccatccg acagtgtaaa gctggtaacg gtgaatttag 1450921 tgaattcgga acaaaatcag caagtcgttg aagactttat taaagcaaac aagctgacgt 1450981 ttccgattgt ccttgactca aaaggggaat tgatgaagga gtatcatatc atcacgatcc 1451041 caacatcatt tttgctgaat gaaaagggag aaattgaaaa aacaaaaatt ggcccgatga 1451101 cagcggaaca actgaaggaa tggacggaag aatagctgag agcatagact ctcagctttt 1451161 ttcatataga gaagaagtga ataaacatta atgataatta ttatcaaaaa gaaattaaaa 1451221 taattataat tgaaattctc ttcgtgcgtg ctataataaa ggaagacatc aagaaataac 1451281 tgacgataaa gctgcctttt gggcagcgat tttgttttta taagagaaat gaagatgatt 1451341 tacgttctca attagagagg agaattcgat atgaatgaac aagttatcgt tcaacgcgac 1451401 ccgcatgagc cattgaaaac agacaagagg gaaaaaaact gggcacagca cgcggagctt 1451461 attgcagcac ttgtatcagg cgctcttatt ttggcaggct ggctcttatc cggatatcag 1451521 gtattatcca taatactttt cttgctggct tttgtgatcg gcggatttgc taaagcgaag 1451581 gaaggaatcg aagaaacact cgaatccaaa acgctgaatg tagaactttt aatgattttc 1451641 gctgccattg gttccgcctt gatcggatac tgggcagagg gtgctatttt aatatttatt 1451701 ttttccttaa gcggagcttt agaaacatac acgatgaata aaagcagcag agatttaacg 1451761 tctttaatgc agcttgagcc tgaagaagcg acattgatgg tcaatggtga aaccaaaaga 1451821 gttccggttt cagacttgca ggccggtgat atgattgtga tcaaacctgg agaacgcgta 1451881 gcggcagacg gtatcattga atcgggctcg acaagtcttg acgagtcggc tttaacaggt 1451941 gaatcaatgc ctgtagaaaa aaacacaggc gacactgtat tcacaggaac ggtgaatcgc 1452001 aatggctcct tgacagtccg tgtcacgaaa gcaaatgaag attcgttatt cagaaaaatt 1452061 atcaaactgg ttgaatcagc gcaaaatagt gtttcacccg cgcaggcttt catcgaacga 1452121 tttgaaaatg cttatgtgaa aggtgtgcta attgcggtgg cgctcctttt attcgtcccg 1452181 cactttgcgc tgggctggag ctggagtgaa accttctacc gcgcaatggt gtttatggtt 1452241 gtcgcgtcac cttgtgcgct tgtcgcctct attatgccgg cggcgctgtc cctgatttca 1452301 aatggcgccc gcaacggtat gcttgtgaaa ggaagcgtct ttcttgaaca gctgggctca 1452361 gtgcaaatga tcgcctttga taaaaccgga actgtaacaa aaggccagcc tgccgtagag 1452421 acgatcagaa tagcagaagg attcagtgaa gcggaagttc ttgaggctgt ctatgccatc 1452481 gaaacgcaat caagccatcc gctcgcccaa gccataacgg cgtacgctga aagccgcggc 1452541 gtgaatcagt ccggctacat atctatagaa gaaacctcag ggtttggcgt tatggcagaa 1452601 gtgtcgggtg cgaaatggaa ggtcggtaaa gcaggtttta tcggcgagga aatggcagca 1452661 caatttatga aacaaacagc atcagatgtc attcaaagcg gtcatacaat tgtatttgtg 1452721 aaaaaggatg atcaaatagc aggctgtatc gcactgaagg accaaatcag gcctgaagca 1452781 aaagaggtca tggaagaact gaaccgactt gggattaaaa cggccatgct gacaggagat 1452841 cacgaagaca cggctcaagc gattgccaag gaagccggca tgacaactgt cgtggcagaa 1452901 tgcctgcctg accaaaaagt gaatgaaatc aaacggttaa aagaagaatt cggaacgatt 1452961 gcaatggtgg gtgacggaat caatgatgcg ccggcactca aagcagcgga tgtcggcatt 1453021 gcgatgggcg gcggaacaga tgtagcactt gagaccgctg atatggtcct catgaaaaac 1453081 gatttgaaaa agctcgtaaa catgtgccgc ttgtctcgga aaatgaacag gatcatcaaa 1453141 caaaatatcg tgttttctct agctgtaatc tgcctgctga tttgtgcaaa ctttttgcag 1453201 gcgatggaat tgccatttgg cgtgattggt catgagggca gcacgatttt agtcatacta 1453261 aacggtttaa gactcctaaa ataaaaccag cagcctaatc aggctgctgg ctttttatgt 1453321 atcaagcttt cccttcattt ttgtctttat cagatctttt cataactagg atgagagcga 1453381 gggtgcagca aaggaaaccc gctgcacagc ctatgataga gctgtaataa taaaagccca 1453441 ccatcttcat cccgataaaa ggagcggaaa ttcccaaaac cgttaagagc ataactgctt 1453501 ttcgtctgaa aaaattcatc agcaaacgga acaacccccc tgcgattgaa cgttactgtc 1453561 agtatacagg aagaggagca ggaaataaaa tgcattagaa aatgaaggcg tcgtgaaagg 1453621 caaacaccgg taaaacctgt tacaatggaa gacagaacaa tgcattgcaa atggcaggga 1453681 ggaacaagaa gtgaatagaa tacaacgcgt ctcttcatgg ctgaaggaag cggggcatac 1453741 tgccgcattt attcatacga aagaaaatgt tttttactta accggttttt acacagagcc 1453801 gcatgaaaga ttaatggggt tatttatttt tcaagaagag gagcctttct ttgtttgtcc 1453861 aggaatggaa gcaggacagg cccgcaacgc aggctggaat catgaaatca ttggctatgc 1453921 ggatcacgaa aatccgtggg agctgataga gaaggctttg aaaaagcgaa atatcagcat 1453981 acatatgctt gcggtagaaa aggattcaat ctcgctgtca cgtgcagaac agctgaagca 1454041 tgcgacgggc ggggctcaat ttgtttcagc agaagaaaca ctcaatcaat ttcgcctgat 1454101 taaagatgac aatgagattc gtttgctgaa agaggcggca aagcttgcag attacggtgt 1454161 tgaagtcggc acagccgctt tgcgtgaagg catcagtgaa gtggaagtgc tcgctcaaat 1454221 tgagtatgag ctgaagaaaa aaggaattca gggcatgtct ttctctacaa tggttttatt 1454281 cggagaaaaa tctggccagc ctcatggaaa tcctggtaca gccacgttga agaaaggtga 1454341 ttttgtttta tttgatctcg gtgttattct tgatggctat tgctctgata ttacaagaac 1454401 gtttgcatac aaaaccatca atccgaagca ggaggccatt tacgagactg tgcttcaagc 1454461 ggaaaaagcc gcgattgagg caagcaaacc cggtgtgaga atcggagatc tggatttaac 1454521 tgcccgcgga atcattgaaa aagcgggata tggtgattat tttcctcacc ggcttgggca 1454581 tggactcgga atttcagtcc atgagtatcc atcaatgagc caggccaacg atacactgct 1454641 gcaggaaggc atggtctaca cgatcgaacc ggggatttat gtgccagaga tcggcggcgt 1454701 acgcattgag gatgacgttc acgtaacaaa ggacggagca gttgctctga cccaatatcc 1454761 aaaggatttg atcatactgt aatagaaata aaaaaggact ttgttctcga catcgtcctt 1454821 ttttatctgc attaaataaa aaaatcatca aatgttcgaa agggtttaat ttcatgtttt 1454881 tggttgagag gttttacagc aagacagctg ccaccgagaa cagtgagaca taacccaatt 1454941 aaaatgaaga aacccatgtg atcttctcct ttcagctaaa aacacaaaaa gatatctggt 1455001 acgtccatat catattgtat gaaacgcatt ccagatcaag gggatttaga aagaagggaa 1455061 tctatggcta atattaaaga cattgcagag aaagccggtg tctctgttac aacggtttcc 1455121 cgagtcataa acaatcatcc atacgtcagt gaagacaaac gaaaaagagt gtttgaggca 1455181 atggaatcat tggagtacac gagaaatatt cacgctgtac atttgtcgaa aggattttca 1455241 aacatgattg gtgttgtctt gccgacggtt aatctgccat attttgcaga gctgattgca 1455301 ggaatagccg acgcagccgc ggaatccggg gttcacctct ctttattcca aacaaactat 1455361 gaagtacaaa aagaaatctt tgcgctgtcc caattaaagc agcgccaggt tgacggcctg 1455421 attttttgct caaaggcgct tgctgatgag aaactcatgg aatgggaggg cccgattttg 1455481 ctttgccaga attcagataa tgcccgcttc ccaaccatca gcattcctca ccaagaagca 1455541 tttcggaacg gcttggacta tttaattgcc aaagggcaca aaaaaatagc catctgtttg 1455601 gcaagaaaaa aaggcatgaa cagccatttt cgaatcaaag cctacaaaga ggcattggaa 1455661 gagatcggcg aggcatttcg tgaagactgg gtaattgaga aagcgattac aatcaatgat 1455721 gggaaggcgc tttttcataa atggaatacg tggaaggaaa agccgacggc tatttttgtt 1455781 gccaatgacc aagtctcagc agggcttttt cttgaagcaa agaaccagcg ggtgtcagta 1455841 ccggatgagc ttgcaatctt aagcgttgat aaccacgaaa tcagccaagc gcttggaatc 1455901 acaacgatcg atattcagac aagggaaatg ggaaagcagg catttgccat attggaaaaa 1455961 agaattcaag gacagccgat tgaaaggaaa gttctggatt accgtctcat cgaaagatcg 1456021 actgtttagt gaatgcattg aaaaaaggtt tgacgtgcat tctgttcgtt atgtacgata 1456081 tgaggtattg aatgacaaag gagctgagga tcgtgaatgg gtccttcaca gtgaaaaagg 1456141 tactgaataa taacgtatta attgcttctc atcataaata cagcgaagtc gttttaatcg 1456201 gaaaaggtat tggtttcgga aaaaaacaag atgatgtcat tgaagataaa ggctacgata 1456261 aaatgttcat tttaaaagac gagaaggaac aaaagcagtt taaaaagctc cttgactatg 1456321 ttgatgaaaa gctcgttgat atttcaaacg atgtcatcta tcacataagc aataggacga 1456381 atcactcatt aaatgaacat attcacattg cgttgacaga ccatatcgca tttgcgatca 1456441 aaaggcagca gcagggattt gatatgaaaa atccatttct aatggagact cagtcactat 1456501 atcctgagga gtaccaaatt gccaaagaag tcatagatat gatcaatgaa aaagcgggac 1456561 tctgccttcc ggaaggggag attggtttta tcgctctgca tatccattca gcgttgacaa 1456621 accgtccgct gtccgaggtc aatcagcact ctcagctcat ggcgcagctt gtcgaggtga 1456681 ttgaagactc atttcaaatg aaagtaaata aggaaagtgt caactatttg cggctgatca 1456741 ggcatatcag atttacaata gaaagaatta aaaaagaaga accgactaaa gaaccagaaa 1456801 aattaatgtt gttattgaaa aatgaatatc cgctatgcta caatacagct tggaaattga 1456861 ttaaaatctt gcagcaaaca ttgaagaaac cagttcatga ggcggaagcg gtttatctga 1456921 cgcttcatct gtaccgatta accaataaaa tttcataaat tcagtttatc cttataacgt 1456981 gttactgatt cgatcaggca tgagtgattg agggaaaaaa acgggaagtt cattctcgtt 1457041 cttttgcgca cccaattttg ctcatgcctt tttgttgtgt aaaagggcaa atgtaaacgg 1457101 ttaaactgga agacttacgc ctgtgaattc gttgtcatga tttttagctg taaggtcaga 1457161 ctagtaaaaa gaggaggtca attcttatgt ttaaagcatt attcggcgtt cttcaaaaaa 1457221 ttgggcgtgc gcttatgctt ccagttgcga tccttccggc tgcgggtatt ttgcttgcga 1457281 tcgggaatgc gatgcaaaat aaggacatga ttcaggtcct gcatttcttg agcaatgaca 1457341 atgttcagct tgtagcaggt gtgatggaaa gtgctgggca gattgttttc gataaccttc 1457401 cgcttctttt cgcagtaggt gtagccatcg ggcttgccaa tggtgatgga gttgcaggga 1457461 ttgcagcaat tatcggttat cttgtaatga atgtatccat gagtgcggtt cttcttgcaa 1457521 acggaaccat tccttcggat tcagttgaaa gagccaagtt ctttacggaa aaccatcctg 1457581 catatgtaaa catgcttggt atacctacct tggcgacagg ggtgttcggc ggtattatcg 1457641 tcggtgtgtt agctgcatta ttgtttaaca gattttacac aattgaactg ccgcaatacc 1457701 ttggtttctt tgcgggtaaa cgtttcgttc caattgttac gtcaatttct gcactgattc 1457761 tgggtcttat tatgttagtg atctggcctc caatccagca tggattgaat gccttttcaa 1457821 caggattagt ggaagcgaat ccaacccttg ctgcatttat cttcggggtg attgaacgtt 1457881 cgcttatccc attcggattg caccatattt tctattcacc gttctggtat gaattcttca 1457941 gctataagag tgcagcagga gaaatcatcc gcggggatca gcgtatcttt atggcgcaga 1458001 ttaaagacgg cgtacagtta acggcaggta cgttcatgac aggtaaatat ccatttatga 1458061 tgttcggtct gcctgctgcg gcgcttgcca tttatcatga agcaaaaccg caaaacaaaa 1458121 aactcgttgc aggtattatg ggttcagcgg ccttgacatc tttcttaacg gggatcacag 1458181 agccattgga attttctttc ttattcgttg ctccagtcct gtttgcgatt cactgtttgt 1458241 ttgcgggact ttcattcatg gtcatgcagc tgttgaatgt taagattggt atgacattct 1458301 ccggcggttt aattgactac ttcctattcg gtattttacc aaaccggacg gcatggtggc 1458361 ttgtcatccc tgtcggctta gggttagcgg tcatttacta ctttggattc cgatttgcca 1458421 tccgcaaatt taatctgaaa acacctggac gcgaggatgc tgcggaagaa acagcagcac 1458481 ctgggaaaac aggtgaagca ggagatcttc cttatgagat tctgcaggca atgggtgacc 1458541 aggaaaacat caaacacctt gatgcttgta tcactcgtct gcgtgtgact gtaaacgatc 1458601 agaaaaaggt tgataaagac cgtctgaaac agcttggcgc ttccggagtg ctggaagtcg 1458661 gcaacaacat tcaggctatt ttcggaccgc gttctgacgg gttaaaaaca caaatgcaag 1458721 acattattgc gggacgcaag cctagacctg agccgaaaac atctgctcaa gaggaagtag 1458781 gccagcaggt tgaggaagtg attgcagaac cgctgcaaaa tgaaatcggc gaggaagttt 1458841 tcgtttctcc gattaccggg gaaattcacc caattacgga tgttcctgac caagtcttct 1458901 cagggaaaat gatgggtgac ggttttgcga ttctcccttc tgaaggaatt gtcgtatcac 1458961 cggttcgcgg aaaaattctc aatgtgttcc cgacaaaaca tgcgatcggc ctgcaatccg 1459021 acggcggaag agaaatttta atccactttg gtattgatac cgtcagcctg aagggcgaag 1459081 gatttacgtc tttcgtatca gaaggagacc gcgttgagcc tggacaaaaa cttcttgaag 1459141 ttgatctgga tgcagtcaaa ccgaatgtac catctctcat gacaccgatt gtatttacaa 1459201 accttgctga aggagaaaca gtcagcatta aagcaagcgg ttcagtcaac agagaacaag 1459261 aagatattgt gaagattgaa aaataagggt gttagtacgc cgtgcttgtc agatgacaag 1459321 tacggttgta tgatataata ttgtgaagta ataaagcttt aagttaaaag gagaatgata 1459381 aaaatggcac aaaaaacatt taaagtaact gcagattctg gaatccatgc tcgtcctgcg 1459441 acagttcttg tacaaactgc tagcaaatac gacgctgacg ttaatttaga atataacggc 1459501 aaaacagtta accttaaatc tattatgggt gttatgtctt taggtatcgc taaaggcgct 1459561 gagatcacaa tctctgcttc cggagctgac gaaaacgatg ctcttaacgc tttagaagaa 1459621 acaatgaaaa gcgaaggact cggcgagtaa tgcaagaatt aaaagggatt ggtgcttcag 1459681 ccggcatcgc gattgcaaaa gcgtaccggc ttgaagagcc agatttaacg gttgaaaaga 1459741 aaaacatctc tgattctgaa gcggaagtaa gccgttttga tgaagcgatt gcacgttcaa 1459801 aagaagagct cgaaaaaatc aaagagcacg ctttgaaaga actgggtcag gataaagctg 1459861 atattttttc tgctcacctt ttagttctca gtgaccctga gcttctgaac cctgtgaaag 1459921 aaaaaatcag cactgattca gtgaacgctg aattcgcttt aaaagaaacg tcttctatgt 1459981 tcgttactat gtttgaatct atggacaacg aatatatgaa agagcgtgcg gcagatatcc 1460041 gcgatgtaac aaaacgcgta accggccacc tgcttggcgt cgaaattcca aacccaagca 1460101 tgatctcaga agaggttatt attgtagctg aagacttaac accgtctgac acagctcaat 1460161 taaaccgtga gttcgtaaaa ggattcacta ctgatatcgg cggacgcaca tctcactctg 1460221 ccatcatggc acgttctctt gagattccag cagttgttgg aacgaaagct gctacaggca 1460281 cgatccaaaa cggcgtgact gttatcgttg acggtatcaa tggcgatgtc attattgacc 1460341 catctgcgga aactgtaaaa gagtatgaag aaaaacataa tgcttatttg gctcaaaaag 1460401 ctgagtgggc gaagcttgtc aatgaaccga ctgtctcaaa agacggacat catgtagagc 1460461 ttgcagcgaa catcggtact cctgatgatg taaaaggtgt tcttgaaaac ggcggagaag 1460521 cagttggcct ttaccgtaca gaattccttt acatgggaag agatcagctg cctacagaag 1460581 atgagcagtt tgatgcttac aaaacggttc ttgagcgtat ggaaggaaaa tcagtcgtcg 1460641 tgcggacact tgatatcggc ggagacaaag agcttcctta cctgcagctt cctaaagaaa 1460701 tgaacccgtt cctgggatat agagcgattc gtctttgcct tgaagagcaa gaaatcttca 1460761 gaacacagct tcgcgcgctg cttcgtgcaa gtacatacgg aaacttgaaa atcatgttcc 1460821 ctatgattgc gacagttaac gaattcaaag aagcaaaagc gatccttctt gaagagaaag 1460881 aaaagctcgt aaaagcggga caggctgtat ctgacgatat tgaagtcgga atgatggttg 1460941 agattccgtc aactgcagtc atcgctgatc agtttgctaa agaggttgat ttcttcagta 1461001 tcggaacaaa cgatttgatt caatacacaa tggcagctga ccgtatgaat gaacgtgtat 1461061 cttacctgta tcagccatac aacccggcaa tccttcgctt aattacactg gtaattgaag 1461121 cagcacacaa agaaggaaaa tgggttggca tgtgcggaga aatggcagga gacgagattg 1461181 cgattccgat ccttctcggc ttaggcttag atgagttctc aatgagcgca acgtctatcc 1461241 ttccggcaag aacacaaatc agcaaattgt ctaaacaaga agctgagtca ttcaaagaga 1461301 aaatcttatc tatgagcacg acagaagaag ttgtcgcgtt cgtaaaagaa acattcaagt 1461361 aatgtacaaa aaccagacgg cctccggcct gtctggtttt tttcataagt aagggtatag 1461421 aaggacacaa taacatggct aggagggata gtatgtcaaa ccaatttaac gcaggagata 1461481 ctgtttatgt gatctacaga aatccgcacg ccgccaatgt agcccacata aaggaagccg 1461541 aaattgtgca ccatccatac catgaaggcg agctttccct gtttatttat gaaacctatc 1461601 atccattcgc agaggacgat gctgtgtttg caagctatga agaagctaaa tcgctttaca 1461661 aagaactgtt tgatattgat ccgtatgagt aacaaggaaa tcattacaac tcatatcctt 1461721 tccgcctagt gagaaaagta acgttagtaa aggaaaagga tgtggcatca tgcagaaccc 1461781 atttgttccg cagcttgtgt atatagaacc gagggcgctg gaatatccgc tgggccaaga 1461841 attacaagat aaatttgaga atatgggtat tgaaatcaga gaaacgacat cccacaatca 1461901 ggtgcgtaat atccctggga aaaatcatct tcagcaatat cgcaatgcga aatcaacttt 1461961 agttatcggt gtccggaaaa cattaaagtt tgattcatcc aaaccctcgg ccgaatatgc 1462021 cattccgttt gcaacaggct gcatggggca ttgtcattac tgctacctgc aaacaaccat 1462081 gggatcaaag ccgtatatca gaacttatgt aaacgtcgaa gagattttag atcaggcaga 1462141 taagtatatg aaggagcgcg caccagagtt cacaaggttc gaagcatcat gtacgtcaga 1462201 cattgtagga attgatcatc tgacacacac gctgaagcgc gccattgaac attttggcca 1462261 aagtgatctc ggaaagctcc gatttgtaac gaaatttcat catgtcgatc acctattaga 1462321 cgcaaagcat aacgggaaaa cgagattcag attcagtatt aatgccgact atgtgattaa 1462381 aaactttgag ccgggaactt cacctcttga taagcggata gaagcggcag taaaagttgc 1462441 aaaagcaggc tacccgctag gctttattgt tgctccgatt tatattcatg aaggctggga 1462501 agaaggatac agacatctgt ttgaaaagct agatgctgct ttgccgcagg acgttagaca 1462561 tgacattacg tttgaattaa ttcaacaccg ttttacaaaa ccggccaaac gagtgataga 1462621 gaaaaattat ccgaagacga agctcgaatt agatgaagaa aagcgccgtt ataaatgggg 1462681 ccgttacggg atcggaaaat atatttatca gaaagatgaa gagcatgcac ttcgagaggc 1462741 acttgaatcc tatattgata cctttttccc taacgcaaaa attgaatatt tcacttaaac 1462801 gggctgttgt gatcaacagc tcgctttttt ataaaaaaca tttttccatt ccatcaaaac 1462861 gccgtaattc aatgattctt tatcctccaa ataattgctg actacacgaa taggtgaacg 1462921 cccgcaacgg aggagaaagg acagcacagg gtcgtttttc ctgccttcca tcacatcttc 1462981 aacgtactga acagcgctga tctcgtgtgc gtatttataa tacaaaggaa tgcggccgcc 1463041 gccgagaagg cgttccagtc ttttatcaac agtcagctca tacatcgtat tcatcagcca 1463101 ttttccgatt ccaagctttc gataatgagg agaaacagaa atatccacta catataaagt 1463161 atttccatga ggttcatgat ttttaatcga tccgttgtca gttgcttgtg cccatgtatg 1463221 atcaggagaa tcaggctcaa attgtacaat aagagcagtc atggaaccga taattctgcc 1463281 attgatgagc gcgcataaag cgccttccgg aaaggttttg atatggctgg caagctggtc 1463341 ctctgaccac agcaattcct ggggaaacgg aggagggaaa cattcttctt gaagagaaat 1463401 cagcctctcg atgtcagtct cagtgtagtt tctaatggtc agagcctcaa attttctgcc 1463461 gtcatgcaca tacatttgtt ttagtatgat catcactctc cttatgttgt ttcattataa 1463521 cgaagattga attttcagta aatatattcc gattttctta taatttattt tttgattatt 1463581 catttttcaa acgaaagggc cgatatagaa attaggaggg gattggtttg tttaaaaaac 1463641 ttcacatgaa gattgctgtt tttgtttcga ttatgttaat catcacagtt gttctcttaa 1463701 tgctgtcttc ttatttgacg ctaaaaccga tgattacaga ggatgggaaa aatacaactc 1463761 aaaacgtgac gcagtcactt gaacaaaata ttgaattgca attaaagagt tatgccattt 1463821 cgttatcaag attggctaat ggggaattaa cgcatacatt tgtaacgaaa ccaagtaaag 1463881 aagcttctcg gctgtttcac gatgacatta agcaaatcaa agacaacgat gattatgttg 1463941 cgatggctta cataggcacc gcaaaaaaag aaatgtttac atatccaaaa gcggatttcg 1464001 ctgaggatta cgatccaaca tcaagaccat ggtataagct tgcagctgaa accccggatc 1464061 aagttgtttg gacggaacct tataaagatg tcgtgacagg agacatgatt gttactgcat 1464121 cgaaagcgat cttagacagg caaaaagtga taggggttgc cagctatgac ttgaaactct 1464181 ctgctatcca gagtatggtc aataaacaaa aggtgcctta caaaggattt gcctttttag 1464241 ctgatgcgag cggcaatctt ttagcccatc cgtcaaatca aggaaaaaat atatcaaagg 1464301 atcaaacact gcaaaccatc gcatccgaga aaaaagggat acaagatgtg aatgggaaaa 1464361 tggttgtgta ccaaacgatt ggcgagacag gctggaaggt cggaacgcaa tttgataccg 1464421 atcaattaat gtggatttca gataaaatga atcgggccaa tctttggata tcattgattg 1464481 cgcttatcat aacaattatt ctcagctact tcctggccaa aacgataacc ggtccgatac 1464541 agcagctgat cgtaaaaacg aaagctgttt ccgcaggcga tttaacagtg cgcgcggaat 1464601 caaaatctaa ggatgaagtc ggtattttaa caagagattt caatctgatg gttgaaaata 1464661 tgaaggaaat ggttgagcaa gtgagactct cttcagggaa agtatctgac acctctgaac 1464721 aactaacggc tgtggctgcc gaaactaatg aaacaagcgg acaaattgca aaagcgattg 1464781 aagaagtagc cgcaggggca tcggaacagg cttctgaagt tgaaaccatt aatgaaaaat 1464841 cggaaagcct gtcaacgaaa atcaggcaaa tcgctgagga ggcaggcgga attaaagaac 1464901 gctcaaaatc gtccgaggat gcaagctata aaggacttga cgcgctcggc cagctgctga 1464961 tgaaatcaaa cgaagccaat atggaaacga aaaaggttga aacgatgctg ctggatttgg 1465021 aaaatcaaac taagaatatt gaagaagtcg ttacagcgat ttcaaacata tctgatcaaa 1465081 ccaacttgct tgccttaaat gccagtattg aggcagccag agccggagaa agcgggcgcg 1465141 gttttgccgt cgtagccgat gaagtgcgga agttagctga gcaatcagcc ctttctacaa 1465201 agcatatcag cgagactgtg aagcttatcc agcttgagac aaaagaggcc tctcacgcga 1465261 tggttgaggc aagcagaatg aatgatgaac aaaacagtgc aattcacgaa actggagagg 1465321 tattaaatac gataactgca gaaatgcagt cactggtaca aggtattgat cacatttacg 1465381 cggaaattca aagaatgagt gaagaacagc ttgcgatttc tgaagccatt caaagcattt 1465441 cagccatatc acaggaatca gctgccgcag cagaggaagt gaacgcatca accgatgaac 1465501 agcttgtcac ccttgataaa gtcaaacact caacggaaac actaaaacat gcaagccaag 1465561 agcttatgaa cacaattgca aaattcacat tgtaatccaa ttacatcccc aaacatcatt 1465621 tgttttgggg attttttatt ttataagatg aatagatatg gtagtctaga aaatgaagga 1465681 aaaatgataa attttaacta aaatctaaac gaaacatctg ggaggaatga ccttgaaaaa 1465741 aacaattggt tttatcggtc ttggagtaat gggaaaaagc atggcatcac atattctcaa 1465801 tgacggccat cctgtattgg tgtacacccg gacaaaagaa aaagcagaaa gcatacttca 1465861 aaaaggcgcg atctggaaag atacggtcaa agatctttcg aaagaagcgg atgttatcat 1465921 cacaatggtc ggctatccca gtgatgttga agaagtgtat ttcggaagca atggaattat 1465981 tgaaaacgca aaagaaggtg catatcttat tgatatgacg acatctaagc cttcgcttgc 1466041 gaagaagatt gctgaagcgg ccaaagaaaa agcattgttc gctttagacg ctcctgtttc 1466101 cggtggagac atcggtgcac aaaacggaac actcgcgatt atggtcggtg gagaaaaaga 1466161 agcttttgaa gcctgcatgc cgattttctc tttaatggga gagaatattc agtatcaagg 1466221 accggctgga agcggacagc ataccaagat gtgcaatcag attgcaattg cagccggtat 1466281 gatcggtgtt gctgaagcga tggcttatgc ccaaaaatca ggcctagagc cggaaaatgt 1466341 tctgaaaagc atcacaacgg gcgcagccgg aagctggtca ttgtcaaatc ttgctccccg 1466401 tatgctgcaa ggcaactttg aaccgggatt ttatgtgaag cattttatta aggatatggg 1466461 aattgcacta gaggaagcag aattaatggg ggaagaaatg ccaggcttgt cgctcgcaaa 1466521 atctttatat gacaagctag ctgctcaagg tgaagaaaac agcggaacac agagtatata 1466581 taagctttgg gtgaaataaa aaaagattgc ctgtacgaaa caggcaatct ttttttatta 1466641 ttttccgatg aattgttgtg tccagatgct tccagactca acgtaaccaa caccgatgtg 1466701 agtaaagtta gggtttagaa tgttttttct gtgtccttca ctgttcatcc aagcttttac 1466761 tacttcttct ggtgtctttt ggcccttcgc aatgttttca cctgctgttt tgtagctgat 1466821 tccgaaagat ttcatcatat caaacggtga gccgtatgtt gggctttggt gatcaaagta 1466881 gtttttgtct ttcatatcct gagattttgc gcgtgcagat ttgcttaacg tttcatcaat 1466941 ttgaagcggt tttaagcctt gtttttgtct ttctgcattt gtaagttcaa caactttttt 1467001 ctcatatgca cttacagatg aaggtgcaga cgttgttgtg tttgtttttt cagcagttgc 1467061 gggtgcttta gaagcagtgt tttgatcagc agctgctttt tcagtagtct tttgtgcagg 1467121 ttttgccgtt tctgtctttt gaacatcctg aactttcacg ttagattgct tcgcatgttt 1467181 ttgaagaagc tgcttcatct ctttttcgtt tgcagcgttt aacgttttga tatttgtgtt 1467241 aatatgcagt tttttcactg catcgttaag tgacatgttt tgtactgtgt tccccgtttt 1467301 tactgtaacc acaggctggc aggagagttc tttcgctgat gcttgctgta cgcccccgaa 1467361 tgtgaataat ccaaccgcag cggcagcaga taaaataaat gctttcttca ttagttcgta 1467421 acctcctaga gttgtttgtt tctacagaaa aatcataaca tagctttttt gtcataaaga 1467481 ttccagcact ttcctttgac aaatagagat tgtcattttc gtaaagtaaa tccgttgaat 1467541 cactaagaat aagggaatca gcggtatata tgattttatc gtaccgttac atagcttcct 1467601 tttttttgaa ccgttagtta tattttaatg tgtttttata ttgacagctt tttttactcc 1467661 ttttcgctgt aacaactatt acaaaggtgt tacaattaat ctcagtatat gtaaatatat 1467721 tgaatgattt gagaggggta accagaagtg actgaaatag gacgtgaacc aaagaaaaag 1467781 agcaaaggaa acagagcaat cagaatgaac ctttttttcc tagctgtctt tgttctattc 1467841 actgcattaa tttttaagct cggggttgtt caaattgttg aaggcgaaca gcatgaagaa 1467901 gacgctgaga aatcaaatgc aaaaacagct tactatcctg cgcctcgcgg gaagatgtac 1467961 gacagaaacc agaaagttgc tgtcgacaac cagagcgttc cagaaattgt gtatgtatca 1468021 acatctagca caaaaacaga agataaaatc aaaacagcga agcggcttgc ttctttcatt 1468081 catattgata ccgaattttt gaaggaaagg gatcttcgtg attactggat cgcagctcat 1468141 ccgaaaaaag ccgccgctct gcttaaggaa tcagaaagca atctgaaagg agaccaggct 1468201 tacaagcttc aaatagagcg tgttccggat caagaattaa aggctattca gcaagatgac 1468261 gaagaaatgg aaactgctgc gatatataca aggttttcaa gcggaaatgc ttacgaacct 1468321 caaatcgtaa aggcaatgaa tccaaataag agcaatagca atggaaaaaa cggagcgctg 1468381 cttgatgaga agaaaaactc ctcgcaaaga ccaaaaaatg acttaacata tgatgaaatt 1468441 tccattgttt ctgagcattt agaagaactt ccgggaatcg atatcgtaaa cgattggaca 1468501 cgaaaatatc cttatgacaa aaccctttat tctgttttcg ggggcgtcac gacacctgat 1468561 cagggcctgc tgagcgaccg gaaagatttc tacttaacaa gaggctatgc gaataatgac 1468621 agggtgggaa aaagttattt agagtatcaa tatgaagaat atttaaattc gcataaagaa 1468681 aaagtggaat acgtagaaga taataaagga aatgtcgtca gccaaaaaac cattgataag 1468741 ggcagcaggg gatacgatct tcagctttct tttgacatgg agcttcaggc aaaggtagaa 1468801 aagatcattg aagaagaagt aagaaacagc cgtgcacgcg gaaattacat gcttgacaga 1468861 gcctttgccg taatgatgga cccgaataac ggcgatattt tatcaatggc agggaaaaag 1468921 atagatttaa aaaccaacaa aattgaagat tatgcgatag gggcatttac cacccaatat 1468981 gaaatgggat cagcagtaaa gggggccacc gtgctagccg gctatcagga cgggatcccg 1469041 cattataaat attatatcga tgctccaatg cttttaggaa cgaatcttat aaaaaaatct 1469101 tatactaata tgggaaccat caatgaatta accgcattgc aaaaaagttc aaacgtatat 1469161 atgttcaatg ttgccatgca tattgcaggc gtaacataca agccgcatgg atctctcccg 1469221 gctgatcaga acgatctact gaaaatgaga aactattaca gccagtttgg tctgggagta 1469281 aagacaggta ttgatctccc gcaggaatca gccggaatgc aaaccacacc taaaactgta 1469341 ggaggattaa ttttagactt agcaattggc caatacgata catacacacc gcttcaaatg 1469401 gctcaataca tctcagtaat cgccaatggt ggctatcgtg ttcagcctag aatcgtcaca 1469461 agtattcata agccaggaaa aaaagaccag ctgggtaagg cgattgaaca taggaaacct 1469521 aaagtactca ataagattaa taattcagag agcgatttga aacaagtaca aacaggcatg 1469581 aaattagtca cttcttcagg gacagcaaaa aatacgttta cagaagatgt atcagggaaa 1469641 acgggaacag cggaaacatt ttactacggc acgaatcgca actggtgggg gaaaaaaaca 1469701 tacaatctga cttttgtcgg ctattacccg tcgaaaaaac caaaagtggc ctttagtgtt 1469761 gttgttccat cagtagatga tgatgataag atcaataaaa ttattgccaa aagagctatc 1469821 cacgcctacg cagagctcga aaaaaaacac agtaaaaaat aaaaaacagg gtgcacaact 1469881 aaaagattgt gtgccctttc ttttattcaa aaattgacgt tcaccataag aatagaagga 1469941 gaatactcat tttctagcga atcatactag gtaaaagtca atctgtatat gtcgaaacac 1470001 gatgatcatg caaaggaggg attctgtgga acaggatacg cagcatgtta aaccacttca 1470061 aacaaaaacc gatattcatg cagtcttggc ctctaatgga cgcatcattt atatatctgc 1470121 caactccaaa ctgcatttgg gctatctcca aggagagatg atcggatcat tcctcaaaac 1470181 gtttctgcat gaggaagacc aatttttggt tgaaagctat ttttataatg aacatcatct 1470241 gatgccgtgc acctttcgtt ttattaaaaa agatcatacg attgtgtggg tggaggctgc 1470301 ggtagaaatt gttacgacaa gagctgagcg gacagaacgg gaaatcattt tgaaaatgaa 1470361 ggttcttgaa gaagaaacag gccatcaatc cctaaactgc gaaaaacatg aaatcgaacc 1470421 tgcaagcccg gaatcgacta catatataac ggatgattat gaacggttgg ttgaaaatct 1470481 cccgagtccg ctatgcatca gtgtcaaagg caagatcgtc tatgtaaaca gcgcgatgct 1470541 ttcaatgctg ggagccaaaa gcaaggatgc tattattggt aaatcgtcct atgaatttat 1470601 tgaagaagaa tatcatgata tcgtgaaaaa caggattata cgaatgcaaa aaggaatgga 1470661 agtcggaatg attgaacaga cgtggaaaag gcttgatggc acacctgttc atttagaagt 1470721 gaaagcatcc ccgaccgtct acaaaaacca gcaggctgag ctgctgctgc tgatcgatat 1470781 ctcttcaagg aaaaaattcc aaaccatcct gcaaaaaagc cgtgaacgat atcagctgct 1470841 gattcaaaat tccattgata ccattgcggt gattcacaat ggaaaatggg tatttatgaa 1470901 tgaatcggga atttccctgt ttgaagcggc tacatatgag gatttaattg gcaaaaacat 1470961 atacgatcag ctgcatcctt gcgatcacga ggatgtaaaa gagagaatcc aaaacattgc 1471021 cgagcaaaaa acagaatctg aaattgtcaa gcaatcctgg ttcacctttc agaacagggt 1471081 catctatacg gagatggtct gcattccgac gacctttttt ggtgaagcgg ccgtccaggt 1471141 cattcttcgg gacatctcag agagaaaaca aacagaagaa ttgatgctga aatcggaaaa 1471201 attatcaatc gcagggcagc tcgcggcggg aatcgcccat gagatccgca accctcttac 1471261 agcgatcaaa ggatttttac agctgatgaa accgacaatg gaaggcaacg aacattactt 1471321 tgatattgtg ttttctgaac tcagccgtat cgaattaata ctcagtgaac tgctcatgct 1471381 ggcgaaacct cagcaaaatg ctgtcaaaga atatttgaac ttgaaaaaat taattggtga 1471441 ggtttcagcc ctgttagaaa cgcaggcgaa tttaaatggc atttttatca gaacaagtta 1471501 tgaaaaagac agcatttata taaacgggga tcaaaaccaa ttaaagcagg tattcattaa 1471561 tttaatcaaa aatgcagttg aatcaatgcc tgatggggga acagtagaca ttatcataac 1471621 cgaagatgag cattctgttc atgttactgt caaagacgaa ggggaaggta tacctgaaaa 1471681 ggtactaaac cggattggag agccattttt aacaacaaaa gaaaaaggta cggggcttgg 1471741 attaatggtg acatttaata tcattgaaaa ccatcaggga gttatacatg tggacagcca 1471801 tcctgaaaaa ggcacagcgt ttaaaatttc atttccaaaa aaataaaaac aacggcttaa 1471861 acgccgttgt ttatcgtctg cattgcttca cgttttttta atacaaataa ttctaaacgg 1471921 tctaggcctt ctctcagcgt gtccattgag catgcaaaag acagccttac atatccttca 1471981 ccatatgttg agaacgagct gcccggcacg agtgccacgc cagcgtcttc caaaagagcc 1472041 atactaaaat caaatgaagt cattccaaat gatttaatag aagggaagat ataaaacgca 1472101 ccggacggtt taactacgtc aagtcccatg gaaacaagac ggtcataaac atagtccaga 1472161 cgttttttgt attgttctct cataatcaat gcatcgtcaa agccgtttgt gacagcttca 1472221 agcgcggctt tttgagaaat ggatgaggcg cacgacacat tgtattgatg aacctttaaa 1472281 atgtgctttg caatgtcttt cggtgcaaat aaaaatccaa ttctccaacc ggtcatgctg 1472341 tgtgattttg acaacccgtt aatgacaatc gtttgatccc gcaaataggt tgcgatggag 1472401 taatgcggtc tgtcatatgt taattcactg tatatttcat cagacaatac gaagacattt 1472461 ctgcctttta agagagctgc gatgcttttc agttcttctt cagataaagt cacgccggta 1472521 gggtttgacg gataaggaag cacgacacac ttggtgttgg gtgtcagagc atcttcaatc 1472581 agccgggcgg taagcttaaa gccgtgtgac gtagtatcaa caatgacagg cttggccccg 1472641 cacaaattga taataggttc atagcccgga taaataggcc ctggcataat gacttcatca 1472701 ccgggagata aaatcgtccg gaatgcagca tcaatggctt ggcttgcgcc tgttgtgatg 1472761 ataatttcag attcagcatc atagttgaaa tccgcttttt tcttcatata aagctgcaca 1472821 gcttgtctca gctccaggta gccggcattc ggagtatatg acgtcacgtt ttcatcaatg 1472881 gctttttttg cggcagcttt cacatgatgc ggtgtgaaaa aatcaggctg gccgattgta 1472941 agtgaaatga cgtcttcgtg ttgggctaca agattcgaga atttgcgtat tcctgaaatt 1473001 tcgatctctc ttgctttcgg attcagcaaa tgttccataa ttcatcacct taacaaatat 1473061 aatgagttta tcctatttta ccactagctg atcatttgtc acctttttaa ctgatatatt 1473121 tcgattgtat gcgccttttt tctaaacata cctttctttt cagaaaaaaa gaagacaacc 1473181 agcgatttga ttgtctttat tgtatcatgt tctattattg tttatatgtg ccaatttcat 1473241 taatagccat aatcaaaatg aaggtcttcg tgccaaatca gatacggagg atgctcttct 1473301 tgaaggtcag ctgattcttt cttcatattc aggtaagttt cttcactgat atcctctaaa 1473361 acagtcattt cgttttcttt aaatattact aaggtaccca ttatttacac ccttctttgg 1473421 aaaaatcctt gactatttta tcactgttag ttggaaagtc aatggttatt aggaaaaaag 1473481 tttctttttt gaggaacgcg gcttgttgcc ttcggaattc gattttgaag agctgccatt 1473541 cactttttac aaattacgcc gatatataca gtacaatact gaatgcgaat agcgagggat 1473601 tgaattgtcg ttacaacaat acgaaatttt attggattct ggtacaaatg aattagaaat 1473661 tgtgaagttt ggcgtgggtg aaaatgcttt cggaattaac gtcatgaagg taagagaaat 1473721 tattcagcct gtcgaggtga catcagtgcc tcactcccat cagcatgtag aaggaatgat 1473781 taaactcaga ggagaaatcc tccctgtgat cagtctcttc tcattttttg gagtagagcc 1473841 tgaaggatca aaagatgaga aatatatcgt gactgaattt aataaacgga aaattgtttt 1473901 tcatgtcggc tctgtttctc aaattcacag agtatcctgg gaagcgattg aaaagccgac 1473961 atcgttaaat caaggaatgg agcggcacct taccggtatt attaagctcg aagacctgat 1474021 gatctttttg cctgactatg aaaaaattat ttatgacatt gaatcagatt caggtgttga 1474081 cacgtataat atgcataccg agggcttcga tgaaagaaga actgataaaa agcttatcat 1474141 tgtagaggac tcaccgcttt tgatgcgcct cttgcaggat gaattaaaag aagcagggta 1474201 caacaatatc gcttcgtttg aaaatggaaa agaggcatat gaatacatta tgaaccttgc 1474261 tgaaaacgaa actgatttat caaaacagat tgatatgatc atcactgata ttgaaatgcc 1474321 aaaaatggac ggacacaggc tcacaaagct gctgaaggaa aatccgaaaa gctcagatgt 1474381 gccggttatg attttctcat cgttaattac ggatgatctg cgtcaccgcg gcgaagttgt 1474441 aggcgcagat gagcaaatca gcaagcctga gatcagtgat ttgattaaaa aagtggatac 1474501 gtatgttatt gaataaataa aaacagccgt tgccagaaag aggcacggct gtttttattt 1474561 taaaagtaac tctcgccaag ttttttaaag accggtttat ggtaagctgg ctgctggcga 1474621 tttggcacta gcggcttttc tttcatgccg acatattctt gcaataggtg tttcgctttt 1474681 gttaaagaca tttgagcttt aggatttcga tacgattgat taagtgtacc taaatgcgga 1474741 agatgttcga agtcttcttt agttggaggc atgtgaaaat agtagtctcc gattgagata 1474801 agcacgtccg attgctgttg gctgaacctt ggattttttg aaaaatgaag ccctattttc 1474861 tttcctttac cttctttgac aagcttttgc aaagcccgtt ttttcagcag atataggtat 1474921 ttagggttgg gggcggtttt tgcatggcgg ttcacagtgt aaactgcttt tgaaagattt 1474981 tctacggttg gctgcagatc tttcgtatat gcatggtcgt ccattatttc tctcctttgc 1475041 tcttatcaat ttctatatgt ttagattata cttttttaaa gttgaaatgc aaatattgaa 1475101 tgtaaaaatg cgcttttttc taagaaaaaa agcgcatttt taacctgcat tatacagatc 1475161 ttgccttctt tttcggctgt tcttgaaatg cttcctgaac attcacttcc acagcctgag 1475221 cactgtattt tggcagtgca ataaaataaa aaataaaaac gagcaggata ataacaccca 1475281 tgccgtaata aagataatca atgtttgaaa caaacttagg gaataacagc gcgactaagc 1475341 cgagtgtcaa agattgtgca aacatcataa aagggtcctg catgccgctt acacgtccca 1475401 tcagttttgg atgaacaatt tttggcatcc accctccgat tgcaatgttg atcggtccga 1475461 tacacattcc cagtgcaaaa gctgccgcgt aatacaccca taaaatattg gtgtagccga 1475521 ggacgaagat cagcaaacct gcaatgaaaa tcggtatcga cattaaaaag tgcggcttca 1475581 cttttttaga gatgagcgtg ccgattacgc ttcctgccag aagcccaaac ccgagtgcga 1475641 tcgtaaatac agacgtatgc cactcataac ggtcaggcgc caatccatat ttcattgtaa 1475701 acatcggcaa tacggcgaat cctccattga caaatccaaa aatgaagaag ccaaaaataa 1475761 gagatgccag caatttgttt tttaaaatat agaggatgcc ttctctaaag tcatttattg 1475821 aatccttaac agaagtcttt ctccagctga atgcaccgtt tggctgtcgg gcttcttttg 1475881 gaatccggca gctgcggatc agcagcccgg aaatgataaa gctgacaaaa tcaagaataa 1475941 tggcgccttc aataccgatt gtgttgtaca taaacgcgcc tatgccgact ccaaacacca 1476001 taaaaatgct aaaaagcatc tgattaagcc ctgccgcttt cgcataatgc tccttcggca 1476061 gaatggcttg taccaaactg ttttctgccg gaaagaaaaa ctttgttaca gcgcttctga 1476121 taaataagat acaaaaaaca agaggaatat tgccggtaaa taaagtgaaa aaaagcacga 1476181 cagtcaggcc tgctctgatc caatcacaat tttctgccac cttttttcta tcaaaccggt 1476241 ccgcgacgac tcccacgatc agaaatacaa atatggtcgg aagagaatac atcagctccg 1476301 ccaaggtcgt atatgaaggc tggctgctga atcggtccag caaaaaaaaa gcaaaggcca 1476361 tgttgcctac tgtcgtgccc atttgagaag cgagtgctgc gaaaaataga cgaacaaaat 1476421 tacgattttt aaatatatcc ataaaaacgc tccttaccct aaaggtccca ctttatcata 1476481 ttataaaccg cctgtttttg aaacaaataa gaaaacatta ccggttaatc gtgactctcg 1476541 ttccgtttgg cacaattgaa gcaagttcga tcacgtcttt gttatgcatg cgaatgcagc 1476601 ctttagaaac agccttacca atcgaagcgg gattattcgt cccatgtatt ccgtagtgct 1476661 gctttgaaag gctcagccaa taagcgccaa atgggccgcc gggattgcgc tggcggttaa 1476721 taatgtaaaa ctcgccagta ggcgtttgcg ttagtatttt accaacggcg atgggatagg 1476781 ttttcattac ccgattattt agggacagcg taagggtctt cgctccgatt gagactgcga 1476841 tatgatacgg aattgtataa gggtccggca gtccggggat gactatggac tgtcccgcgg 1476901 tgagccctgc ctgcagtgac ggattagcct ggagtaatgc agccgtgctg attctgaaat 1476961 cagccgcgat gctgttcagt gtatcacctt gcttcacctg gtacgtaagc agtttcctca 1477021 tcctcctttt ttacttataa gtattgatga ggagcccatc ctgctacatt aatttgtgct 1477081 ttttaaggtg aagacagtga tttcaggctt ggcaagaaac cgcaaaggca gcctggtcat 1477141 cccgaggcct cggtttacgt aaatatgagt gctgcccgtt tgatacattc cctctgtgta 1477201 gacttttcca tatggaggcg taataatcgg tccgtaaaaa ggcagctgaa tctggccgcc 1477261 gtgtgtatgg ccggaaagct gaaggttcac gggataatct gttgttttca aggctgcatc 1477321 aggttcatgg acgagaagaa tggaaaaaag tctgtcgctc agccttgaaa gggtgccttc 1477381 ataatctggg tttcccagca ttaagtcatc aagcgaagca atctcgattt tgctgccatc 1477441 tgcgagtgac aatgtttgat agccattgcg atataccgtg aaacctccgg ccgtcatcag 1477501 gcttttgtaa acggcagttc catagcctcc gtgatcatga ttgccgtaaa tacaaagctt 1477561 gccgaaggga gcattaagct ttctcaataa tggaatgact gcctggtggt gctggtacgt 1477621 atcaggatta tcaataatat cacctgtaaa aacaatgaga tcaggtttag attcattaat 1477681 tgtaagaatg acagttttta aatcttcgag agtaaagtaa tcactcaagt gtgcatcgct 1477741 gaactgcacg attttaaaac cgtcaaatcc gtgcgggatg agagagcttt ttattgtgtg 1477801 ttcggttgtc tcgatcatat gcggctcgag atacctggca tagccatatc ccccgccggc 1477861 cgttaaagcc ccggcagcaa gagcgccgaa cattcctttt agaaattgtc ttctggacat 1477921 ctttttcatt tcaaaccaac ctttaataga gtttttctat tatatcatct gtatctgata 1477981 aaaatctcat atgagcatgt gctgacagag gcagggatat aatgatagaa tattattgaa 1478041 tgaataatca ttcacaattg gagggataaa catggaaaaa aaggcggtaa ttattaccgg 1478101 cgggtcaagc ggcatgggaa aagcgatggc aaaaaaacag gctgaattag ggtggcacgt 1478161 tatggtgaca gggaggaacc atgaggcact tgaggaaaca aaaaaagaaa ttcagacctt 1478221 tgagggacag gtcgcttgtt ttcaaatgga tgtccgttcc gattccgccg cttcagacat 1478281 gattaaagaa gcggtaaaag cctttggccg gcttgacgcg ctgattaaca acgcggccgg 1478341 aaactttatt tgtccggcag aaaagctgac gcccaatgga tggaaagccg ttattgagat 1478401 tgttttaaac ggcacatttt tttgcagcca agcagcggca aggcattgga ttgaccagaa 1478461 gcagcagggt gtcattttaa atatggcagc cacgtacgct tggggagcgg gagcgggggt 1478521 cgttcattcc gctgcagcca aagcgggggt attgtcattg acaagaacgc tggccgttga 1478581 atgggggagc aaatacggca ttcgtacaaa cgcgatagcc cccggaccga ttgaacgaac 1478641 aggcggtgcg gagaagctat ttgaatcgga aaaagcgatg gcccgcacga tgaacagtgt 1478701 gccgctcggc cgattgggca caccggagga aatcgccgct ttggcagcgt ttttgctttc 1478761 tgatgaagca tcctatataa acggggattg tatcacaatg gacggggggc aatggctgaa 1478821 tccttatccg ttttaatctg aatatttata agtgaatatt taagttatta agaactttta 1478881 tgttcgaatg taatacctcc acaattaacc ttcttcctat ccaatttgat aacacataga 1478941 gctttatttg tttatgaggt gttgtgtcat acgtaagcca cctaatatat gaaaggtata 1479001 ttttaaaagg ggagacgaaa tatgaagaac ttagatttca aataaaacat tcatataatt 1479061 acttcgttaa ctaaaaagag aaattataag aatgaaaggt ttcaaggtta catcagattg 1479121 ggaggaaggt aatataatgg acgagatggt attattaact caggaatggc tcaatgaaac 1479181 gtacaaagga aaaagtggct acaattccat tgaggaaaat gggaaaactg gctggaaaac 1479241 aatgtatgca ttaactagag cattacaact agaattggga attacacaga cttccgacag 1479301 ttttggtcct acaactttaa gaaagcttaa agaattaggc ccgatttcta cgtcaactaa 1479361 ttcaaaaaaa aatattgtga aaattattca aggtgctctt tattgtaaag gttatggtcc 1479421 aggtggatta acgggtacat ttggtcaggg aacgaaagag gcgatagcag aaatgcaatt 1479481 gcatatgggg ctttctaaaa cagacggtgt agtaacgcct aaggtgttta aagctttatt 1479541 aaacatggac tcttatatcc ttttaaatgg ggcgtcagag aaagttcgtt caatacagca 1479601 atggctaaat aataaatatt acaatagaga gaatttctac tttatgccct gtgatggcct 1479661 gtattcaagg gatactcaaa agtctcttgt ttatgcaata cagtacgagg aagggttaag 1479721 tgatagtata gctaatggga attttggacc aactactcaa agattgattc ctgtattaag 1479781 aattggagaa acagatgaaa aaaacagttt tattcattta tttcaagctg ctctaatctt 1479841 taatggctac aatgttcctt ttgatggagt atactctgaa tctgtaagat caaaagtaaa 1479901 ggcttttcag tcttttgcaa aattacaaca gagtggtact gccgactttc aaacatgggc 1479961 ttcacttcta gtaagtactg gagaccccaa tcgaaaagga gttgcttgtg actcaattac 1480021 tcaaattaca tcggacaggg cggagtccct taagagggca ggttataaga ttgtagggcg 1480081 gtatctaaca aatgcgccgg ggagtacact aaataaaaaa atacaaccag gtgaattaga 1480141 aactatctta aaatcaggtt taaatgtttt tccgatttat caaacctatg ggggagcaac 1480201 aaattatttt aataaagaac aaggaaagaa agatgcgttt gctgcttata aagcagcaaa 1480261 agaatacggg tttaaaaata acactgtaat atactttgca gtagattatg atgcatatgg 1480321 taacgattta aacaacaata ttattccaca cttcgaaggt ataaatgaaa taatgaacgg 1480381 ttttttaggt tcaacttaca aaattggtat ttatgcccct aggaatgtat gtactatagt 1480441 ttctaaaaaa ggtttagcat ttgcaagttt tgtaagtggt atgtctactg gctttagcgg 1480501 aaacttagga tatcctttgc cttacaattg ggcgtttgac caaatttcaa caattactgt 1480561 tggaaatggt tctggaatga ttgaaattga taatgatatt tgttcaggtt tggataatgg 1480621 agttaatacc ataaatatag tgccttcaga gaataagaag ttttttgatc aaattgatgt 1480681 tttatatgaa actgctgaaa aatatgctca aatgcaaagc gacttaaata atggggtaaa 1480741 aaaaacacaa ttagctaatg agttggttgc ccagtattta agaaaggatg actacaaagg 1480801 gtggaagtgg gtccctaccg caggccagat tgatcctatt tatcgtgaat gggcagtaaa 1480861 gcgctagggg aagacctagt aaatggaatt gttgatccta tatcaaaaac tgtcatagga 1480921 acgcagcatc ttatggcaac ttataatgcc attatttata gtggtggtta ctctcaaaca 1480981 ctacgagatt ttgctggttg gactggagat ctattaacaa caatacagga catgaaatta 1481041 cacgctcaag aatttaattc gccttatgat gcggctatga aaataatagg taatatgtat 1481101 caatttagcc tagatgattt atttagtgat gtagatgcaa ttaatctagc gaataaaaca 1481161 tcagttggtg ctaatgcaca acctctaaat atcgcaatta gagattatta tagtaataat 1481221 gactgtatga ataggttcac tcaatttgta aataatagat ttgatggttc gttagacaaa 1481281 attttctctg aagcagagta ttatttaaat acaaaccttg acccagttgt tgttccaatt 1481341 aggttagcct ttaaacgtgc ttttgatgtt gaggattata gtgaagagat tggaaaaata 1481401 acagcacaag catttagaga tgttatcgag aaaaaaatga tatctgaata aactgcaaaa 1481461 caagcgaacg ttaaaactgg tcgttcgctt gttttatttt ctatttaaat ttatgatata 1481521 atttttaaag attaaggagt gattcattga agaaattgtt aaaaaagtta gttgtattat 1481581 ttttaagcag tttagttatc atctttaatg tttggtactt tattatttgt gctttttccc 1481641 cagagtatta tcaaaataca aatcttactt ctaatgaaat aataagattt gaaaaactat 1481701 accacataga ttttcctgat gaaacaaaat ttattaaagc tagagagtat ttggctgggc 1481761 ccggaggaga tacgtcagct gtattatatg tgtctctgcc aaccaagcgg gtagaaaaag 1481821 ttttatctga ttacacgtat atgaaaataa actatactga caatgtcggt tcaatgtatg 1481881 gagttgacgt ttcaaagagt gtcgccggtt taacaactct tacatttggc acttacgata 1481941 aaaaaggaac tttctataat atgaaacatg atgatgattg gatgtataaa ggcactgact 1482001 ggaatcttta cttttggaca gctgctagtt ataatgctgt tatttttgta tttgttttgg 1482061 ttattgtgaa acaaatgaat aaaattctta attaaccagt atgtagattg ataatctcaa 1482121 aaaaattttc ctcttctttt aacatactcc atacgaccta cttttccata ctatgatttt 1482181 tttgaaattt gtggtgtagt tataattgtg cgtataatca gacaaagata gagaagcagg 1482241 tgataacatg ttggatccac ttgatatttt aacgaacatt gatgatgtcc ttccatatta 1482301 ccaggcgatt tttagtgccg aggagcagaa ggttgtcgga tatgaggtgc ttggacgaat 1482361 tttggcagat tcagaaatcc aaagtctcgg gcccttcttt ttagatgcgg ggatacccga 1482421 agaatataaa ttagaggttg ataacagaat tatccgccag gctcttgacc gctttttaga 1482481 ggcggattct gatctgctga tttttatgaa tcaggatgcc aatctgctga tgctggatca 1482541 tggtgaaagc tttctggagc ttctgaaaga atatgaagcg aagggaatcg aactccaccg 1482601 ttttgtgctt gaaattacag agcacaattt tgaaggggat attgagcagc tctaccatat 1482661 gcttgcatac tatcgtacat acggaattaa aatcgcagtt gacaacatcg gaaaagaaag 1482721 cagcaacttg gacagaatcg cgctgctctc accagatctg ttaaaaatcg atttgcaggc 1482781 gctgaaagtg tcacagccgt caccgtcata tgagcatgtg ctgtacagca tatctttatt 1482841 agcaagaaaa atcggtgcgg cgctgctgta tgaagacatt gaggcgaact tccagcttca 1482901 gtacgcctgg agaaacggag gccgctattt tcagggctat tacttagtgt ctccatctga 1482961 aacgtttcta gagagagatg tattgaaaca aagacttaaa actgaatttc accaatttat 1483021 cacacatgag aaaaagaaac tggagaccgt ctatgagcac tctgaacagt tttacaaacg 1483081 agtgcatcag gctgtgacct ctttgagaaa aaacaatctg tcttctgatg atgactttat 1483141 taaaaagctg gcggaagagc tgacagattg cagcttcagg atttacatgt gtgatgaaga 1483201 aggcgatcag ctgacgggaa atgtgtttaa gcaagatgga gaatggattt atcagccgga 1483261 atatgcggaa aagaactgga gctggcgccc ttattttctg gagaacatta tgagaatgag 1483321 aaatctcaga aaaggttttt tcagtgatct gtacagtgat ttggaaacag gtgaaatgat 1483381 cagaacgttt tcatatccga tggatgatca gatgtattta tttatagact tgccttattc 1483441 ttatttatat gagcaggacg gactgattta acggctgaaa ggccgttttt tttatgaaat 1483501 gaaaaaaata tcaaaaaacg attgacattg atactgagaa tcattatcat ttaattatag 1483561 agagaagcta ctctctgttc cccaacccct ctatcagatc aagatccgaa aaaacttggc 1483621 gctacccccg ccaagttttt tatttgtcaa agcataggac aatccaatga aacaataaac 1483681 ctaactagtg gtaaacgttt aacacgggga gaaacattga gtgccgaaca cccctgacac 1483741 tgctgcacgg gtgaggagga aaattcgttc tgaaatgatt atttcagttc cgttgtttac 1483801 ctctatccag catgactccc attgattatg gccacgcggg acttcaccat aaaattcaaa 1483861 agaaggtttt gacaaagttg caaaaaggca ttcttaatgc tgccaaagat tcgaaaaaaa 1483921 ttataattat gtgcatgaca ttcaaaaaaa gcctcaaact aaagaaaaat agtttttttc 1483981 actttttttc tttgcttaaa ttcagcagtg aaaatgccat cctgtccgac tttatggtat 1484041 gatgctcaat agaacttgta ttataataaa tacttgttga tttgaagttg ctttttgaaa 1484101 ggagtctttt tttagaatgt cacaattaat gggtatcatc acacggctgc aaagtctgca 1484161 agaaacagcg gaagcggcta acgagccaat gcagcgttat ttcgaagtga atggtgagaa 1484221 aatatgcagt gttaaatatt tcgaaaaaaa tcaaacgttt gaactgacgg ttttccaaaa 1484281 gggtgaaaaa cctaacacat atccgtttga taatatcgac atggtttcca tcgaaatctt 1484341 tgaacttctt cagtaagatt cctgaaatag ggggaacaag cttccgcctt tgcaaaagta 1484401 atcgaaataa acggtaagga acatacttgt ttcatggttg taaatccttg aaaaggagtg 1484461 tcgtgatggc tgattctttt ctgttttata atctttcaga agcacagatg acctttcaag 1484521 atgtgatgga acggcttaaa gcctttgttc aaaaggaccc ccgttcttct tatgtgttat 1484581 cgatcggaac cgattcacag gtttaccgcg attacacaaa gtttattacc gcattgcatt 1484641 tgcatcgtac aggcaaggga gcttggggct gcttgaaaaa tcatacagtc gacagaccca 1484701 tacatagcct tcgggagaag atttcgttag aaacggcgta cagccaagaa acggccgctc 1484761 atattcttga tggacactta atggatatta ccgatctgct cctgcccttt accggtgagg 1484821 gggcggatct tacctttgaa gttcacttgg atattgggaa aaaagggctt acaaaagatc 1484881 tgatccaaga aatgactgga cgtattacct ccatggggat tgaggccaaa ataaagccgg 1484941 attcatacac tgccttcagc tatgcaaatc gtttcacaaa ataatttggc tgaaaaagcc 1485001 aaggtaaatg tcgaattatg cggttgacgt ttgttatctg attacttatt ctagcggtag 1485061 agctgaaagt aagttgtctt gctttcagag gtattcagta taaaacaggg ggcctgattg 1485121 cgaatgagtc ttatcggtga acgatttaca gaagaagaac aaaaacttct gctgaatatc 1485181 ctgatcaacc atgagtatgc catcgagcta ttaagcagtg agatcaacga tatagagaca 1485241 gggaccaaaa acgttgacgg aaccacctac aaaaaacttg taacgctata cgaccgattt 1485301 cgatttgaaa attaatggga caccctataa ttgatactcc acaaagagta tcttttttat 1485361 tgaaaggaaa cttttcgaca aatactgata aagtttatat tattgcaata tagggaatgt 1485421 attgatgatg aaaatgaaaa ggggtcgaaa acatgataag cttacaatca gatcaacttc 1485481 ttgaggcaac agtcggacaa tttatgattg aggcggacaa agtagcgcac gtgcaagtcg 1485541 gaaataacct tgagcatgca ttattagtat tgacaaaaac cggatacaca gccatcccgg 1485601 ttctggatcc ttcctaccgt ttacatggct taatcgggac aaatatgatc atgaacagta 1485661 tttttggact tgagcgaatt gagtttgaaa agcttgacca aatcactgtt gaggaagtca 1485721 tgctgaccga cattccgcgc cttcatatca atgatccgat tatgaaggga ttcggcatgg 1485781 tcattaataa cggatttgtc tgtgttgaaa atgacgagca ggtatttgaa gggattttta 1485841 cgagaagagt cgttttaaag gaattgaata agcatatacg ctcattgaat aagtaggctg 1485901 tacggtccta tttttattat ataggcagag tgaaaaaaga aagcgcatac ataatttaaa 1485961 cgagaatagg gcttgaataa gaaactaaga ttttattaga atgggagata agaaaaactt 1486021 attgataaca aaaaggagga cgacatgcag cttcaagagc ttcatatgct cgtagtttta 1486081 gctgaggaat taaatatgag aaaggcggca gaacggcttt ttgtatctca gccggcttta 1486141 tctcagcgct tacaaaccat tgaaaaggcg tggggaacaa aaatcttttt aagatctcaa 1486201 aaaggattaa cggtaacgcc cgccggtgag aaaatcattc agtttgcgaa tgatgtgaca 1486261 ttagagcagg aaagaataag agaaaatatt gacgagcttg aaggtgaaat tcacggcaca 1486321 ttgaagcttg ccgtcgcctc cataatcggt cagcattggc tccctaaagt cctgaagacg 1486381 tatgtggaaa agtatccgaa tgcaaagatc tcgctcataa ccgggtggag cagcgaaatg 1486441 ctgaaaagct tgtatgagga tcaggttcat atcggcatta taagaggcaa ccctgagtgg 1486501 aaggggcgca aagattactt aatgacagat catctgtatt tagtggatac tgaaatttcc 1486561 tgcatcgaag atattgccca tacagaacgt ccgtttatcc agtttaaaag tgacagcact 1486621 tattttcagg aaattcagca ctggtggcat caaaaattta aaacgtcgcc gaaacagacg 1486681 atattggttg atcagattga aacgtgcaaa cagatggcgc tgcacggaat cggttatgcc 1486741 attttgccgt ctgttaccct tcaaaatgaa gataaagtga ataaaatgcc tcttttagac 1486801 atgaaagggc atccgatcgg tcgggataca tggttattag gttatgagcc tgcctttgaa 1486861 ctgaaacaag ttcaagcttt tgtacaagtg ataaaggata tgctggatca ggaaaatcca 1486921 ttttaaagac agcgaggtgc tgtctttttt ttatttatct gttgacaatg aaaatcatta 1486981 tcatttaaag tgatacatat gatattgaaa atcattatca actaatgggg tgataacatg 1487041 gctaaagcct tgattacata tgccagcatg tcaggaaata cagaagacat tgccttcata 1487101 ataaaagata cgcttcagga atatgagttg gatatcgatt gtgtcgagat aaatgatatg 1487161 gatgcgtctt gtttaacctc ctatgattat gtactgattg gcacctatac atggggggac 1487221 ggcgatttgc cctacgaagc ggaggatttt ttcgaagagg tcaaacagat tcagcttaat 1487281 ggtttaaaaa cagcctgctt cgggtctggc gattattctt atccaaagtt ttgcgaagcg 1487341 gtgaatttgt tcaatgtcat gctgcaagag gcgggagctg ctgtttacca ggaaacacta 1487401 aaaattgaat tagcgcctga aacagatgaa gatgtggaaa gctgccgagc gtttgcgaga 1487461 ggttttcttg catgggcaga ttatatgaac aaggaaaaaa tccatgtttc ataaaggggc 1487521 aaccgctgtt acggcatcgg cgttttctgg atattttgtg gcggtacaaa gagaaggcat 1487581 ttttcattac tctttggagc agggctggag aaagcttttt cgtttgaaaa gtaagataca 1487641 ctgtatcagc tacatagggc cttacttatt tggcgttggt gaaaagggaa cagtcattcg 1487701 ttcggctgat gaagggaaaa cctggacgat gtcgagcttt ccgacaaatg caacagtgtg 1487761 ggcgattacc ggcagaaaca acgggtttgt ctgcgcccac ggtaagcatt gtatttatgt 1487821 atcggatgat tttggtgtct catggcgcgt agccaaacct tttgccgaat ttcataatcc 1487881 ccctgttatc cggtcgttat gccttcacgg gggcaatctc tttatcggca cgcaaataca 1487941 cgaatatttt ggcggcattt gggcttacga cattaagcgt gacactgtcc aagttgtcaa 1488001 aaaagaaaaa aaccggatga cggcatccat gctcgtgttc aatgaaaatt ggctggtggc 1488061 ggcgatgggt tctgtgaaag gaaagcacgg tgctgtcact gtaaggaatc ttttgaatgg 1488121 tgaagaattc accatacaat ccagtatgat cagaaatgaa gaatcatttc ttgatctttc 1488181 agaggatgat ggcattatat atgtcactac aacacaagat gaaaatggtt tttcgagaat 1488241 ttaccaggtt gatctcgaag cccggtcgtt aaaatggttc gataccatta agggacatgg 1488301 atggagagtg gccaatcaga aagagaattt cttttgcgca ggcttgtatg aatgtaaatt 1488361 tgtccagccg tacgaagttt cagcaatgat tcattagagg aggaacaagg aattggcgaa 1488421 gattttgctc gtttatgcaa caatgtcagg caacactgaa gctatggcag atttgattga 1488481 aaaggggctt caggaggcgt tagcagaagt agaccgtttc gaagcaatgg atattgatga 1488541 tgcccagctg tttaccgatt atgaccatgt cataatggga acctacacgt ggggagacgg 1488601 agatctgcct gatgaatttt tagatcttgt tgaagacatg gaggagattg atttttccgg 1488661 caaaacatgc gctgtattcg gttccggtga tacagcatat gaatttttct gcggagcggt 1488721 tgatacgcta gaggcaaaaa taaaagaacg cggtggagac attgtgctgc cttcggtaaa 1488781 aatcgaaaat aatccagaag gtgaagaaga ggaagaatta ataaacttcg ggagacaatt 1488841 cgcaaagaaa agcgggtgcg ctgtctgatc actcactggg aactgctaaa acggctgttc 1488901 ctttttttct tgtctttgta tctttccttt gatacagtaa tgaggtagaa aatcaggagg 1488961 aggactatac atatgaaaat gatggacgca aatgaaatta tttcatttat tcaaaatagt 1489021 acaaaatcta cacctgtaaa ggtttacgtg aaaggtgagc tggaaggaat caatttcggt 1489081 gaatctgcga aagcttttat caatggaaac actggtgtcg ttttcggtga atggagcgaa 1489141 atccaaacag caatcgaaga aaaccaaagc aaaatcgaag actatgtggt tgaaaatgac 1489201 cgccgcaatt ctgcgatccc aatgcttgat cttaaaaaca tcaaagcgcg tatcgagccg 1489261 ggtgcgatca tccgcgacca agttgaaatc ggtgataacg cagtcatcat gatgggtgct 1489321 tctattaata tcggttcagt catcggcgaa ggcacaatga ttgatatgaa cgttgtgctt 1489381 ggcggacgag ctactgttgg aaaaaactgc catatcggcg cgggttctgt acttgcgggc 1489441 gttattgagc cgccatccgc taaaccggtt gtgattgaag acgacgtcgt aatcggcgca 1489501 aatgctgttg tgcttgaagg tgtaacagta ggtaaaggag ctgttgttgc tgcgggagcg 1489561 atcgtggtaa acgacgttga gccatacact gtcgttgcag gcacaccagc taaaaaaatc 1489621 aaagacattg atgaaaaaac aaaaggcaaa actgaaatca agcaggaatt acgccagctg 1489681 taaggaaaag tttgataaaa aaggcgtgga taatatatcc acgccttatt cgtataggca 1489741 ggaggaatag aaatgaagat agaggagctc atcgcaattc gcagagatct gcatcgtata 1489801 ccggagcttg gatttcagga gttcaaaacc cagcagtatt tattaaatgt cttggaacaa 1489861 tatccgcaag acagaattga aattgagaaa tggcgaacag ggctttttgt aaaagtgaac 1489921 gggacggcgc cggaaaaaat gctggcatac agagcggata tcgatgcgct ttctatagaa 1489981 gagcaaactg gtcttccatt cgcatcagag catcacggca acatgcacgc ctgcggtcac 1490041 gatttgcata tgacaattgc actcggcatt attgatcatt ttgttcacca cccagtcaaa 1490101 catgatttgc tttttctgtt tcagccggca gaggaagggc ctggcggtgc ggaaccaatg 1490161 cttgagagcg atgtattaaa aaaatggcag cctgatttca tcactgccct tcatattgct 1490221 ccagagcttc cggtaggcac cattgcgaca aaaagcggcc ttctatttgc gaatacatca 1490281 gagctagtca tcgatctgga aggcaaaggg ggacatgcgg catatccgca tttggctgag 1490341 gatatggttg tagcagcaag tacacttgtc acccagctgc aaacgattat ctctagaaac 1490401 acagatccgc tagacagtgc tgttattaca gttggtacca ttaccggagg ctcggcacaa 1490461 aatatcattg cagaaacggc ccacctggaa ggcacgatcc gcacgctttc tgaagaatcg 1490521 atgaaacaag taaaggaacg gattgaagat gtagtgaaag gaatcgaaat cggattccgc 1490581 tgcaaaggaa aagtgacata tccgtctgta tatcaccaag tttacaatac gagcggatta 1490641 acagaagaat ttatgtcttt tgttgctgaa catcaactgg cgacagtaat tgaagcaaaa 1490701 gaagcaatga ctggagagga ttttggctat atgctgaaaa aatatcccgg attcatgttc 1490761 tggctcggcg ctgattctga acatgggctt catcatgcta agctgaatcc cgatgaaaat 1490821 gcgatagaaa cagcggttca tgtcatgaca ggttattttt ctgtttatgc caattaagta 1490881 caaatgaaag aataaaattc cataaaatga gcactctagt aaacggaggt gttcaaaaat 1490941 ggctaaaaaa attggaattg aacaatcgtt atcagatgta gaagctgctt taaaagaaaa 1491001 aggatatgac gttgtaatga tgaaaagccc tgctgatgct caaggctgtg actgctgtgt 1491061 cgtaacaggt cttgataata atgtgcaagg gatagccgat acggtaacac aagcacctgt 1491121 cattacagct tccgggatga cggctgaaga aatttgtagc gaagttgaga gcagaattca 1491181 gtaataaaaa aaccgaagca aaaagcttcg gttcttttat ttattctgtt tctttaggga 1491241 aagcgcggtc gaacgcgttc tttatttctt ttctcaacac tcgttcgact cgccactgtt 1491301 ccatattttc tgttttggca atgaccctga ttacaatttc agaagtcccc agttcttgaa 1491361 tcccgatgac atttgggcct tcttttattt gtggaagagc cgctgccgtt tcatcacaaa 1491421 cctgctgtaa aatatgaatc atttcatcaa tatttctttc agccggcact ttaatgtcaa 1491481 caagagcctg catggtacca cgagaatgat tgctcacgtt tgtgatgttt ctgttgggga 1491541 tgtaatgcag tgttccgtca aagctgcgga tttgagttgt ccttaagcca acctgctcga 1491601 caattccgtc aaaggtggaa acggtaatat aatctccgac atccaattgt ttctcaagca 1491661 aaataaaaaa acctgtcacg atatcactga caagcccttg ggcgccaaat ccgacagcca 1491721 ggccgacgat tcctgccccc gctaaaagag cgcttggatc ataatgaaac aaatctagaa 1491781 ccatgacgaa aaatatgaaa atcaatgtat aagcaaatat gttaagagtc aggcttcgga 1491841 gcgtatgtgc acgtccgata gacaagctat tctgctcctc gaattttgca aacagatgtt 1491901 taatgatttt catgcctaat gatcgaacga taaaatagag caatatcata atggcgagtt 1491961 taatgagcag aacaccggca tttgtaatca gtcccgccca atcatattgt ttaataaagt 1492021 ccatgttgag ctccttttct aattgattgc tgcacattga gactagttac cctgtacatg 1492081 accatgttaa acgttttatt caaaaatgtc gaagccaaag acatacatga tttgttaaaa 1492141 attgactcag gaaatctgct tttatataat ggcattgcaa tataactaaa aatggttaat 1492201 caccctttat tttcatgcga ttttgacctt taagccaaac aataaattgg agggatacat 1492261 atggcagaac gtatggtagg taaacaagct cctcgttttg aaatggaagc agtccttgca 1492321 agcaaagaat tcggcaaagt aagtcttgag gaaaacatga aaaacgacaa atggacagtg 1492381 ctgttcttct atccaatgga cttcactttt gtttgtccga cagaaattac agcaatgtct 1492441 gaccgctatg acgagttcga agatcttgat gcagaagtca tcggggtttc aactgatacc 1492501 atccatactc atttagcttg gatcaataca gaccgcaaag aaaacggtct tggccagctg 1492561 aaatacccgc ttgctgctga tacaaaccat gaggtatccc gggaatatgg cgttttaatc 1492621 gaagaagaag gtgtggcttt gcgcggattg tttattatta atcctgaagg ggagcttcaa 1492681 tatcaaactg ttttccataa caacattggg cgtgatgttg atgaaacgct tcgtgttctc 1492741 caggcgctgc aaactggcgg actctgtccg gctaactgga aaccaggcca aaaaacactt 1492801 taattctttc caagaacgaa aagcggtcta gcatattcgt taggcctctc ttttaaaata 1492861 ggagggaaaa agcaatgaaa ttacgtcagc ccatgccgga attgacggga gaaaaagctt 1492921 ggttaaatgg tgaagtgacg agagagcaat tgattgggga aaagccgacg cttattcatt 1492981 tctggtccat cagctgccac ttgtgcaaag aagcgatgcc gcaagtgaat gaatttcgtg 1493041 ataaatatca agatcagctg aatgttgtag ctgtacacat gccccgttcc gaagatgatc 1493101 ttgaccctgg taaaattaaa gaaacagctg ctgaacacga tatcactcag ccgatttttg 1493161 ttgacagtga ccatgcttta accgatgcat ttgaaaatga atatgtacct gcatattatg 1493221 tgtttgataa aacaggacag ctccgtcact tccaagccgg cgggagcggt atgaaaatgc 1493281 ttgaaaaacg tgtgaaccgc gttctggctg aaacggaata ggtatctgac taaatagtat 1493341 ttcctaaaaa cctgacctca tcaggttttt tatttgtgca aaaagcaatg gaagaagagt 1493401 aagaagctta tttttccaaa tttgggtata ggaattgatg atttgtttga ttgatacgct 1493461 aaaaaacaca gctaattttt gatgtttttc ctcaatttta gataaatctc atatctcata 1493521 actcgaaaat tgtagatatt acactaaatt tctttaaaga agtaagtaaa atatatattt 1493581 tcaacattat accaaataaa ctagaaagcc ccttaatccc ttgagaataa aggactcttt 1493641 tgaaaaataa aacattttca gaaaataagg aatttttcat agagtaaata taatagtaaa 1493701 atgctaaaat aatagttgat aaaattactt ttgtaatcta atatcttaat taaagatgtt 1493761 aattttgata gggggtacat tgaggaatgt ttaatgaaag agaagctttg cgcttgcggt 1493821 tagaacaatt aaatgaagct gaagtgaaag tcattcgtga atatcaaatt gaacgtgata 1493881 aaatatacgc aaaattaaga gagctggaca gaaatggaag cccttccgaa atcaaaaagg 1493941 atttccgttc tgaaaaaaaa cctgactctc tgccggttct cgctgagctt gcggctcagg 1494001 aaatcagaag ctatcagccg caatcacagc agcagtctgt tcagcctcag cttcaatcta 1494061 tttcctctct tcctgccggt ataccagacg gaacaacacg aagaagaaga ggaacggcaa 1494121 gaccgggatc aaaagcagct aagctgcgtg aagctgctat taaaacatta aaacgccaca 1494181 acgcggcgat taagagctcg gagcttcaaa aagagattga aaaagaaagc ggtcttgaaa 1494241 tccctaatat gacaacgttt atgcaaagct taattaaaat gtacccggaa gtgaaaaagc 1494301 catatcgcgg gcagtacatt ttagagggtg aaatcgaatc tgcagaatca gcaaacgaat 1494361 aaatataaag aaaaactgct tggcatcgct caagcagttt ttttattgag gttttttctg 1494421 tgaaggtttg ttttcttttt caagattaag cttatacacc cacttttgat aaggcttttc 1494481 ttcagcggct ctgtttttca gctcttcgat tgtatggctc ttggcctggt ctgatgattg 1494541 ggcgtgggca agctgttttt gaagcacatg tatctgtttg gtgacatctt caaggatagt 1494601 ctctacatga tttggctgcg cgtaggccgc tggagcttct tcttccgttt tttctttttg 1494661 tttcgtgccg ccatcaatat cggcaaaatg agaagcaatc caggcatcgc tttcatcaag 1494721 ttgccgttta tacgatataa tagtttcgtg aaataatttt tctttcgttt tttctatgtc 1494781 tagcagtctt tctttcgttt ctatgattcg atctttcata tgatcaactt ctattttaat 1494841 atgttttagc tgatattctt tttctaccat ttgctctttt agacgcccgt tttcggcttt 1494901 tatcaattcg gcttgctgtt ttgcctgaag cagtgcattt tgttcctgct caattgaggc 1494961 ttgaagttcg ctgatccgtt tatgaagatt tttattttct tcttcgattt tgactttcgc 1495021 aatatgaagt ttatgttttt cttcgatttc ggctctgcgt ttataggttt cagcagatag 1495081 aagctcctgc aaaacaacga ttttatcaag cagttcagct cttatttggt gcagggtttg 1495141 gctggtgtgg gaggcatgtt tttcttttgt tgacatatgt gttaattcgg cagacagctg 1495201 ctggagtttt tctttcatat cggtattttc tttgagcagt ttgttatttt tctgatgaaa 1495261 gtagcttgct tcaagttcag aaatcagctt atggcacctt gaaagctcgg attttaaata 1495321 aaggttctcc tgagacacgt cgtggaaaaa aggacctgat cttttcattc gaaccatctc 1495381 cctcatgatg ttaacactac aatatgcaaa tactgaacag ctattcctct ttaataaaca 1495441 gacaagcagt agcgttgagc ctttgctttt gctatgcttt taacgaaact agaggtgaga 1495501 tgatatgaag catgtaaacg tactgctggc agggggagcc tcacgtcgct ttggagaacc 1495561 gaaggcgttt gtcaaatgga agggcaggat gctttacgaa tgcgctaaag aggcacttgg 1495621 agaacaaacg gttatcatca gccgtcccga atttattgat agatttcaag aaaacggtga 1495681 aaatgaagtg tatcaagatg ctgagccatt tcaaggcatg gggccattgg ctggtatata 1495741 taccgctttt aaaaagacag acggtgatct ttatactgtt ctttcctgtg acacaccgct 1495801 gatacaaaga aggacgatgc tggagctcaa acgtctgatg attgccggtg cggacgcggt 1495861 agtcccaatt tcagacggac aagtgcagcc attgattgcg atttaccaca aacgtatcat 1495921 gccagttcta tacgatcagc tttctgagaa gaggttgaga atatcagatt tattaggcag 1495981 aatttcggtt tgttacgtac aggctgaaaa tatcggagca aacccggcag agtttatcaa 1496041 cattaataca cgtgatgatt ttagctgttt ggaagaaaaa tcgaactccc tcaagcggga 1496101 ctgacggggc aataacatga taagatgaca taaaagataa ggagaacagg tttgatggag 1496161 gaacgttatt cacggcaaat cagatttaag caaattgggg aagagggcca gaaaagactg 1496221 gcagacagcc atgtgctgat tgtcggagcg ggagcgctcg gcactgcagg agctgaaggg 1496281 ctttcgagag cgggagtcgg tacgattacc attattgacc gtgactatgt ggagtggagc 1496341 aatcttcaaa ggcagcagct ttatacagaa agcgatgcca aactccgcat gccgaaagcc 1496401 atggctgcca aagagcatct atcagcgatt aacagcgaga tacatattga ggcgtatgtt 1496461 accgaaggaa cagccgaaac gcttgagccg ctgattgaaa aagcagatgt cgtgatcgac 1496521 gcgacagata attttgaaac ccgcatgctg ataaacgatc ttgcccagaa aacaaagaca 1496581 ccttgggtct atggcgcctg tgtaagcagc cagggaatgt tcatgactgt cattcccgga 1496641 gaaacccctt gtctgtcttg tttgtttgag caaattcctg tcggcggggc gacgtgtgat 1496701 actgccggca ttattccgcc tgctgtgcat atcgtttcag catatcagca ggctgaggca 1496761 ttaaagctgt taaccggcca aaaagaagca atacagcggg ggtttgtgac atttgatgtc 1496821 tggaacaatt cgcatatgaa gattaacgtt aatcatgtac gccgtgagga atgcccatct 1496881 tgcggagcta atgcggtata tccttatctt caggattgga acacaccaaa agctgctgta 1496941 ctatgcggcc gtgatacagt gcaggtaagg tcagaatcat taaaaagaat cccgaaacag 1497001 gagctcatta agcggctgaa aacaatcggc aaggtcgagg ctaatgcgtt tttgctgcat 1497061 attttttacg aggatttcag aattgtcatt ttcaatgacg gacgggcact ggtgcatgga 1497121 acaaatgatg tgaaagaagc caactccgtg ttggcaagag tgattggact gtaacaacag 1497181 gaggggtcag aatgctggag aaaagaacac cgataccggt agacgaggca gttcggcgtg 1497241 tctgccattt tcaaaaacaa ggtgaaacag aatgggtggc gcttgaagac agccttcatc 1497301 ggtttttagc cgaagatata actgcggatc accacgtacc tgcgtttgac cgttcgccat 1497361 acgatggttt tgctgtcaga gcgtgcgata cggcagaagc ttcacgtgaa aacccagttc 1497421 ggtttgaagt tattgaccat attggagcgg gagcagtatc tgaaaaagaa cttggcccgt 1497481 ttcaggccgt gcggattatg actggcgcgc aaatccctga aggggcagat gcagtcgtca 1497541 tgattgaact gactcaagcc tttgaggaga atgggaagtc atttatgtct ttaaaacgcc 1497601 gctttcagac gggggataat atttcaaaaa caggtgagga cgctcaaaaa gggagtgttt 1497661 tactgacaaa gggcacccgg gtgacaccag gagtgacggc tcttttggca acattcggat 1497721 acgcatctgt gcctgtcgtg agaaagcctg tagtcgggat tatcgcaacc ggtaccgaat 1497781 tgctgaatgt cagtgatccg ctggaaccgg gaaaaatccg caacagcaat gcgagtatgg 1497841 tatatgcgca agcgatagaa gcaggcgcaa caccgcttta tttagggaaa atctctgatg 1497901 aactggataa aagctttgct gcagttaaag aagcgatgaa aaaggtggac ttcctgatca 1497961 caactggcgg tgtgtcagtc ggtgactttg actttttgcc tgcgatctat gaaaaactcg 1498021 gagcggacgt gctgtttaat aaagttgcca tgcgcccggg cagcgtgaca acggtggcgc 1498081 atgcaaacga tatgctgctg tttggccttt caggtaatcc gtcggcatgc tatgtcggtt 1498141 ttgaactgtt tgtcaaaccg ataatccaga catggctgct caatgaaaca ccgcattcaa 1498201 tttgtgcgga agctgttttg accaaggatt ttccgaagcc gaacccattt acccgatttg 1498261 ttcgtgcgct cgtgcaccat caggaaggga agctgttggc gacacccgtt ggcttagata 1498321 agtcgagctc tgtcacatca cttgcagatg ccaatgcatt tattatcctg ccgggcggta 1498381 cgcgaggcta cgaatctggc agaacggttc aagtgctgct catcagagaa gagaatggaa 1498441 gtgaatggcc ttggtccgtc ctttcccgat cgtccaagtt gtaggatttc aaaacagcgg 1498501 gaaaacaacg tttattgagc gcattcttga aaaagcctct gaacagggag tccatttggg 1498561 ctgcctgaag caccatggtc acggcggtga accgcaaacg ctcacggaag gaaaagacac 1498621 ggaccgttac aaggcggcag gtgctgatgt aacagcggta gaaggtgctg gtgtgttaca 1498681 gctgactgcc cgccgcaatt gggatttggc acggctgatt gagttatacc aatttctcga 1498741 aacagactgt cttctgattg aaggctttaa aaaagcccct tatcctaaag tggttatcct 1498801 aagtgaaaag gaagatctgg aagcgctgca agcagtaaat ataatcgcca tcatctatag 1498861 aaaaaaagag catatgacag agcatcaggg attacccgtt tttcatgcgg atgatccggt 1498921 tgccgtggat tttgtgcttt cacagctgaa gggggaatct gcataatgga acggtttgag 1498981 attacgaaaa cacccattaa tactgaaaac atcatcaaaa aagtggagaa acgggaagcg 1499041 ggagccatta caacatttat tggtacggtt cgggaatgga caaacggaaa aagaacggtt 1499101 cggcttgaat atgaggcata tgaaccgatg gccgtgcaaa tgcttgctca aatcggcgct 1499161 gaaatcgaag aaaaatggga aggtgcctca gctgcgatca cgcaccgtat aggtgtgctc 1499221 gatatcggtg aagcagcggt agtgattgct gtatcttctc cccatcgaaa agccgcatat 1499281 gaagccaatg agtatgcgat tgaacgcatt aaacagattg tgccgatttg gaaaaaagaa 1499341 atttgggaag acggtgagca atggatcggc gaccagctag aaacgacagc ttatccgaac 1499401 ggaaaaccag acctaagcga gggagagcag catgattaaa attcttttat ttgcagggct 1499461 tgctgaacag gccggtacac aagcaataga aatagatatg gaacaagcaa ccacagatga 1499521 aataaaagcg agtctaaaag aacaatacgg tcttgaatct attgatacgg ctatgattgc 1499581 cgttaacgaa agctatgtaa aagaaaatac ctctgtatct tcgggtgaca cggtagccat 1499641 cataccgccg gtcagcgggg gatgaaaacc ggacggcatt tcagccgtcc ggtttttctg 1499701 tatttcattg gcatatcccc aagtatcctc agcatacaat gattttctgt aagcgtttat 1499761 tctacatatg ttactcccta taaagtaaga gactcactcc ataattagac tgaaattttg 1499821 aaaaataata gaaatttatt tcgggtatcg atatagtgaa gatgataaat gttggaaagg 1499881 tgctggatat ggagacattt aaaagattaa aaatgtatta ttggccgtac agaaaagtgt 1499941 ttatgtggtc gcttctagcc atgcttttga tgactgcaat tactgtcgtt tatccgatta 1500001 tcctgcaaat tacgattgat gagatcgtac tgggacggca gtatcagctt gcggcgtggg 1500061 tcagcttagg atttattgcg gtgatggttt tgaaaggaat ggctaccttt tttcatcagt 1500121 atttaggtga tatgttcggg atcaaatccg tttatcggct gagaaatggt ctgtatgaaa 1500181 aactgcagcg gctttctttt tcttactatg ataacgcgaa aacaggagat ttgatgtcca 1500241 ggctgactgc tgatgttgaa gggcttcgtt ttttcttatc atacggtctc gctgagctca 1500301 ttcgcttcgg cctgctggta gccatcagcc tgtcggttat gttttactat tctgttcctc 1500361 tcacgcttgt gacaatagct gttctgccat ttctcgcggt tgcggtatac cggtttgaca 1500421 aaagagtcca tcccgccttc agaggcatcc gcaaatcgtt tgcgaaactc aatacaaaag 1500481 ttcaggaaaa tatcagcggc attaatacgg ttaaatctct ttccagggaa gattttcaga 1500541 tcagcacttt caataaagcc aatgcagaat acagggcgca gtatttacaa acatcatcca 1500601 tttggtctgc gtatttccct ttaatggagt tcattggtaa cacttgtatt gtagctcttc 1500661 tctcatacgg cggttacttg gttatgcaaa atcagctcaa tcccggcgag cttgttgctt 1500721 tcttcagcct tgtcaattat atgatgtggc ccattatgaa cttaggtttt gtcatcaata 1500781 tgttctctca agcaaaagcg tcaggggaac gcctgctcga cattctggaa aaagaagaag 1500841 acattacaga tcatcctcat gctttgcata aacaaaaatt aaccggagat gtccatttca 1500901 aaaatgtttc tcttgcatac ggaaaagaac aaacaaacgc gctgtgcaat gtaagctttg 1500961 aggcaaacag cgggaaggta atcggactgt tgggcccgac aggttcaggc aaaagctcag 1501021 tgacacagct tctcaccaga ttttacagtc ctgttggcgg aatgattacc attgatcaca 1501081 aacccatcac agattattcg ttaaaaaccc ttcgctccaa tatcggggtc gtacttcaag 1501141 aatccttcct gttttcatct acgattagat caaatatttc gtatgggcgg ccggatgcct 1501201 caatggaaga cgtcatcgaa gcggcaaaaa gggcgcaggc tcataacttt attatggagc 1501261 ttcctgatgg gtatgacacc atgctgggag agaggggaat ggggctttcc ggcgggcaga 1501321 aacagcgtat tgccattgcg agagccatct gcttgaaccc gagcatttta atattggatg 1501381 atgccacaag cgcagtagat atgcaaacgg agcacagcat acagcttgcc ttaaaagaag 1501441 tcatgaaaaa ccgcacaacc tttatcgtcg ctcaccgcat ttcttcactg aaacacgctg 1501501 atgaaattct cgtttttaat aaaggacgca ttcgtgaaag gggaacacat catgagcttc 1501561 ttgaaaaagg cggctactat aaaaagattt acgatttgca ataccgtgat gtcaaaatga 1501621 ttaatgagcc gcatgaggtc ggatagggag gggccaaatg aaacaagcga aaaaacaggg 1501681 ggttttagag cgtttctatt actcttcaga tgaaatcatt gaaaagccgt ttaactgggc 1501741 tcaaatgtgg cggctgctga gctatgtcaa accatatcga aaaacaattt tgccgctttc 1501801 ttttctcact gtattgattg gcactgctgt gaagcttgtg atccccattt tgatcggcgt 1501861 ttatgttctt gatcaagcga ttacagggag aaactcggag ctgctgattc agctcatttt 1501921 tattattagc ggtttatatg tcctcaatta cgccgccaat gtgttaagaa tcaggtggat 1501981 gaatcagctt ggccagcatg tcatttacga tttgcgacag catttattta cccatgtgca 1502041 gcgcttatcc catcgatttt ttgatcagcg gtcggcggga tcgatcttag tcaggatcat 1502101 gaatgatatt aactctcttc aggagctctt tacaagcgga gtcatcaatt tgttgaccga 1502161 cttgctgctt ctggccggcg tgattattat tttgtttacg ctgagccctg agctgactat 1502221 agccatcatg gtgacattgc cgattatgtt ttttatttca acaagtctca gaaaaaaaat 1502281 acgccgatcc tggcaaacgg tacggctgaa gcaatcgaag ctcaactctc atctaaacga 1502341 aagcattcag ggcatccggg tcacgcaggc atttacgcag gaagaagaaa acatggcgta 1502401 ttttgacggt gtcaatcagg agaactacga atcatggcgg gaagcaacta gaaaaaatgc 1502461 catgttccgt ccgcttgtag aaatgacgaa tgcgattggg acggctgtct tgatttggta 1502521 tggagccaca ctcatcatga atgaaaccat tacgattggc gtcttcgttt cttttgcttt 1502581 ctatctggga atgttttggg aacctatttc gagactgggt caggtctata atcagctgtt 1502641 aatggggatg gcatcatcag aacggatttt tgagtttctg gacgaacagc caaatgtcaa 1502701 ggagaagccg aatgccattc ataatgaaaa gataaatggg gagatcagtt ttgaagaggt 1502761 tgaattttcg tatgatgaaa aacgaaaagc ccttcacgcc gtttctttct ctattcctgc 1502821 gggatcgacg cttgcgcttg tcgggcatac agggagcggg aagacgacga ttgccaattt 1502881 aatcagccgt ttttatgatg cggccggagg caccattaaa atagacggta taccgattaa 1502941 ggatctttcc cttgccagtc tgcgctctca aatcagcatt gtcctgcaag atacatttat 1503001 tttctccggg accatcatgg aaaatattcg ttttggaagg ccaaatgctt cggatgaaga 1503061 ggtgatgaaa gcgtcccaag cggtcggagc ggatgagttt atttccgatt tagcggaagg 1503121 atacgcaaca gaggtagagg aaaggggcag cgtactgtct gccggtcagc gccagctcat 1503181 ttcatttgca agagcattgc tcgccgatcc ggctattatc atccttgacg aagcaacggc 1503241 aagcattgat acagagacag aagtaaaaat tcagcaagcg ttaaaaacgc ttctgaaagg 1503301 gcgtacagca gtgatgatcg ctcacagatt gtctacgatc cgcgacgccg accgcatcat 1503361 tgttcttgat cacggcagga aaatagaaga agggaaccat gatcagctgc tcgctaaagg 1503421 aggcatttat gccgggcttg tgaaagcgca atacagcaca gcgatagaat aatatgaaaa 1503481 gccttcaata ttgaaggttt ttggaaattt attagaaaaa catgaaactt tttgatatcc 1503541 ttcccgtact atttgttaga tattctcaag gaggttttga aatggaaacg aatgtagaaa 1503601 aaaacagcgg aacggcgact gaaaagcctt cacttttcgg agtaatcaca agtccgtccg 1503661 ttcaatttga aagaataaga gaaaggccgg ctgtatgggg accgcttttg attgttgcag 1503721 caattatcat cgtcggtgcc gtgctgcaat cactcggtac ggattatagt gagcttttga 1503781 aaagccagga tacgcaaggg ctatctgctg aacaaatgga aactgtcgca acaataacca 1503841 aatttggcgg aatggcaggc gctattatcg gcggtatcgc agcattattt attgcccctc 1503901 ttatttattg gctctgtgta aaagtatcag gcggtgttac gacatataaa aaaatgcttt 1503961 ctctcagtct gtttgtctct ttgattagca gtctcggatt attggttaat ggaatcgttg 1504021 cttttacgac tgacgtgaat cctctttaca gcacgacgtc actcgcaggg attatcccat 1504081 ctgacggggc tctcgccagt gtgttaaata cctttgaaat tttcagcatc tggagctttg 1504141 tattattagc aatcggactt cacaaaacgg gaggcatctc aaaaaaagcc gggtggattt 1504201 cagcaatcat tctattcgga attttagttg tattttcgct tttttcaggt ttaatcaatt 1504261 ctgtggcggg tgcataagct catgaaaaaa gtctggatcg gaattggaat cgcagttata 1504321 gtcgctcttt ttgttggaat caatatatac cggtctgccg ctccgacaag cggcagcgcc 1504381 ggcaaggagg tacagacggg gagcgttgaa gaaaatgaaa tctcatcaac ggttatggtt 1504441 cctggcacgc taaaattttc aaatgaacag tatgtctttt atgaagcgga taaagggaca 1504501 ttagaagaca ttaaagtaaa ggaaggcgat aaagttaaaa agggcacggc tttagtcacc 1504561 tatacaaatg agcagctgag cctggaaaaa gaacagaacc agttaacgtc tgaatccaac 1504621 cggcttcaaa ttgaccaaat tcaagaaaag ttaaaagcct tggacagcaa agaaagagaa 1504681 ctggaaaaac aggtaggaaa gaaagaagca gaaaaacaaa tcgaatctga acggacagag 1504741 cttcaaatgc agaaaaaaac agcggagatc gaattaaaac aaaccgagct tcagcggcag 1504801 tcacttgcca accgggtgtc agatttagaa gtgaaaagcg aaattgaagg caccgttatt 1504861 tctgtcaacc aagaagcggc atccaaaaag tcagatattc aagagcctgt catacatatc 1504921 ggcaacccaa aagaccttgt cgtctcaggg aaattgtctg aatacgatac attgaaagtc 1504981 aaaaaaggcc agaaggtcac actcacttca gatgtaatac agggtaaaac atggaaaggc 1505041 acggtttccg cagtcgggct tgttccggat cagcaggaga gcgctgcggc acaaggaaca 1505101 gaacaggcgg tccaataccc gcttcaagtg aaaataaaag gaaatcttcc agaaggaaag 1505161 ccaggcttta aatttatcat gaatattgaa acagataaac ggaaagcaaa tacgcttcct 1505221 tcaaaggcag tcaaaaaaga agatgaccaa tattatgtgt atacagtaaa agacggaaaa 1505281 gcaaagcgag ttgatgtcaa aatcggcgaa gtgacagatg acctgacaga aattaaagag 1505341 gggcttaccc aagatgatca agtcattttg aatccatctg atcaggtgac tgacggaatg 1505401 gaagtgaaat cctaaatgat tcagctttct aatgtgcgaa aaagctacca gatcggaaag 1505461 gaaacgtttg atgttctcca ttctattgat ttggacattc atcaaggtga atatgtctcg 1505521 attatggggc cgtcaggatc aggaaaatcg acgatcatga atattatcgg ctgtcttgat 1505581 cggccgactt ccggtacata tcaattggac ggcgaagaca tttcttcata taaagataaa 1505641 gaactggcgg cagtccgtaa ccggtccatc ggttttgtat ttcagcaatt tcagcttctt 1505701 ccgcggctga acgcaaaaaa aaatgtcgag ctgccgatga tttattccgg gataggcaaa 1505761 aaggaacgtc aagagcgggc tgagagagca ttggaaaagg tcgggttagc cgatcgaatg 1505821 ctccacatgc ccaacgagct gtcgggcggg cagaagcagc gggtggcgat tgcgagggcg 1505881 atcgtgaatg agccgaaatt gattttagct gatgaaccga ccggcgcgct ggatacgaaa 1505941 acaagcgagg cgattatgga tcagtttaca gcattaaatg ccgagggaac gacaatcgtt 1506001 ctggttactc acgagcctga agtagcagat tgcacgaatc ggatcgtcat ggtgcgtgac 1506061 ggaaacattg ttcctgccag ctccggacaa aggagtgtgg gagaatgagc ctgttggaaa 1506121 acatcagaat ggctctaagc tctgtccttg cccataaaat gcgttcgatc ttaacgatgc 1506181 tcggcattat cattggtgta ggctctgtca ttgttgtcgt tgcggtagga cagggcggcg 1506241 agcaaatgct gaagcagtcg atcagcggcc cgggaaatac tgtggagctg tactatatgc 1506301 ctagcgacga ggagcttgca agcaacccga atgccgcagc tgaatctacg tttacagaaa 1506361 acgatattaa aggtttaaaa ggaatagaag gcattaaaca agtcgttgct tcgacttctg 1506421 aaagtatgaa agcgcgttat cacgaagaag aaaccgatgc tacggttaac ggaataaatg 1506481 atggatacat gaatgtcaat tctttgaaaa tcgaaagcgg cagaaccttt accgacaatg 1506541 actttctcgc ggggaataga gtcggaatca tctctcaaaa aatggctaaa gagctgtttg 1506601 ataaaacctc ccctctaggt gaagttgtct ggattaacgg acagcccgtt gaaattatcg 1506661 gcgtgctgaa aaaagtaaca ggcttgcttt ctttcgattt aagtgaaatg tatgtgccat 1506721 ttaatatgat gaaatcctct tttggcacaa gtgatttcag taacgtatca ttgcaggtcg 1506781 aatcagcaga cgacataaaa tcggctggaa aagaagcggc acagctggta aatgacaatc 1506841 atggcacaga ggattcgtat caagtgatga acatggaaga gattgcggcc ggaattggca 1506901 aagtaactgc aattatgacg acgattatcg gctcaattgc aggtatttcc cttttggtcg 1506961 gcggaatcgg tgtcatgaat attatgctcg tatcagtcac agaacggacg cgggaaatcg 1507021 gaatcagaaa atcacttggt gcgacgaggg gacagattct gactcagttt ttaattgaat 1507081 cagtcgtatt gacgctgatt ggcggtctgg tcgggattgg tattggatac ggaggggccg 1507141 cgcttgtttc agccattgcg ggctggccgt cactcatatc ctggcaggtt gtatgcgggg 1507201 gcgtgctgtt cagtatgctc attggtgtta ttttcggcat gcttcctgca aataaagccg 1507261 caaagcttga tcccattgaa gcgctgcgtt atgagtagcc tcatgcaaca tgcatgaggt 1507321 ttttttatgt ttagtgattt ctactatgaa tataaaagac ttttttcatt aaaataagaa 1507381 gaaaatgtcg tacaattgtc cttatttttg tcgaatttac agtttacaaa ccctatagac 1507441 atacgttaat atggagaaac gtgaaagatt ttgatagtta ttgaatgaat ttgaatgatt 1507501 ttagttgcct aaaccgaaaa tagcgtttac aatgaaattg tattcaaaat gaatacgttt 1507561 tcattaggag gtgaagcatg ctaactcctg aacggcatca attgattatt gatcaaatag 1507621 aaaagcatga tgtggtaaag attcaagagc ttataaatct gactaatgct tctgaatcaa 1507681 caatcagaag agatttatcg acccttgaag aacgcggttt tttaaagcgc gttcatggtg 1507741 gagcggccaa gctttccgat atcagacttg aacccgatat gcttgaaaaa tcatccaaaa 1507801 accttcacga taaactgaag attgctgaaa aagctgcttc tcttttagaa gaaggggatt 1507861 gcatttacct tgatgcaggc acgacgacat tgcacatgat tgattttatg gataaaacca 1507921 aagatattgt cgttgtcaca aacggggtaa tgcatatcga tgcattaata aggaaagaaa 1507981 tttcttttta tctgcttgga ggatacgtaa agcacagaac gggcgcgatt attggaggcg 1508041 cttcattggt tgccatggac cagtacagat ttgacaagag ttttctgggg acaaacggtg 1508101 tccatacaga ggctggattt acaacgccgg accctgatga ggccctttta aaacagaaag 1508161 cgatcaaaca ggcaaaacac gcttacgtct tagcagaccc ttcgaagttc ggagaaattt 1508221 cattttcggc attcgccgga ataggcgacg caacaatcat tacgactgac gctgaagagc 1508281 ttacattcga taattaccaa gaaaaaactg tcgtaaaggt agtgaaacca tgatttacac 1508341 tgtaacactt aatccatctg tcgattatat agttcacgtt gaagatttta ctgtaggagg 1508401 cctgaaccgt tcttcgtatg ataccaagta tccagggggc aaaggcatca acgtatcgag 1508461 actgctgaaa agacaccatg tggcgtctaa agcgctcgga ttcgtcggcg gatttaccgg 1508521 agaatatatc aaaacatttt tacgggaaga aaacctggaa acagcttttt ctgaagtaaa 1508581 aggggatacc cgtatcaatg taaagctgaa aacgggtgat gaaactgaaa ttaacgggca 1508641 gggaccgaca atttcggatg aagatttcaa agccttttta gaacagttcc aatctttgca 1508701 agagggagat atcgttgttc ttgcaggaag cattccatct tcactccctc acgatactta 1508761 tgaaaaaatc gcagaggcct gcaaacagca gaacgcacga gttgttctgg atatctcagg 1508821 cgaggctctt ttgaaagcaa cagaaatgaa accatttttg atgaagccaa atcatcatga 1508881 gcttggagaa atgttcggca cggccattac atctgttgag gaagccgttc cttatgggaa 1508941 aaagcttgta gaacaaggcg ctgaacatgt aatcgtatca atggccggag acggagcgct 1509001 tctgtttacg aacgaagctg tttattttgc taacgtgcca aaggggaaat tggtaaactc 1509061 agtcggagca ggggattccg ttgttgcagg tttccttgcc ggaatttcca aacagctgcc 1509121 gcttgaagaa gcattccgct taggagttac ttcaggcagt gctaccgcgt tctctgaaga 1509181 acttggaaca gaagaatttg tccagcagct tcttcctgaa gttaaggtca cacgtctata 1509241 gaggaggaaa cacaagtgaa aataactgag cttttaacga agcatacgat aaagcttaat 1509301 attgagagca aagaaaaaga aaatgttatt gacgaaatgg tcactgttct tgataaggct 1509361 ggaaagttaa atgaccgaca agcctataaa gaagccattt taaatcgcga aagccaaagc 1509421 tccacgggta tcggtgaagg aatcgctatc ccccatgcga aaacggcaag cgttatcaac 1509481 ccggcgatcg cgttcggacg ttcaaaagac ggcgtcgatt atgaatcatt agacggccag 1509541 ccggctcact tagtgttcat gatcgcggcg actgaaggcg caaacaacac tcaccttgaa 1509601 gcattgtcaa gactttcaac gctgttaatg cgtgaagaaa tccgtaagca gctccttgaa 1509661 gctgagtctg aagatgccat catcgacatt attaatcagc acgataaaga tgatgacgaa 1509721 gaggaagagg aagaagaagc ggcaccagca cctgccggaa aagggaaaat tttagcggtt 1509781 actgcatgcc cgacaggtat tgcccataca ttcatggctg cggatgccct taaagaaaaa 1509841 gcgaaagagc ttggtgtgga aattaaggtc gaaacaaatg ggtcaagcgg cattaagcac 1509901 aagctcactg cccaagaaat cgaagatgca cctgcaatca ttgtcgcagc ggacaagcag 1509961 gttgaaatgg aacgttttaa aggcaagcgc gtacttcaag ttcctgtaac ggcgggtatc 1510021 agacgtccgc aagagcttat cgaaaaagcg atgaatcaag atgcgccgat ttatcaaggc 1510081 agcggcggcg gttcagcagc ttcaaatgat gatgaagaag cgaaaggcaa gtctggaagc 1510141 ggtatcggaa acacgtttta taagcacctg atgagcggtg tcagcaacat gcttccgttc 1510201 gtagtcggcg gcggtattct cgttgcgatt tcattcttct ggggaattca ctctgctgat 1510261 ccgaatgatc ctagctacaa cacgtttgca gcagcattaa actttatcgg cggcgacaat 1510321 gcattaaaac tcattgttgc agttctggcc ggtttcattg cgatgagtat tgcagatcgt 1510381 cctggttttg cgcctggtat ggtcggcgga tttatggcaa ctcaagcgaa tgctggattc 1510441 ttaggcggct taattgccgg attccttgcc ggttatgtcg tgattttact gaaaaaagta 1510501 tttacgttta tccctcagtc acttgatgga ttaaaacctg ttttgattta cccgctgttc 1510561 ggtattttta tcactggcgt attaatgcaa tttgtcgtca atacacctgt agcggcattt 1510621 atgaatttct taacaaactg gcttgaaagc cttggtactg gaaaccttgt gttaatgggt 1510681 attatcttgg gcggcatgat ggcgatcgat atgggcggtc cgcttaataa agcagccttt 1510741 acgttcggta tcgccatgat cgatgcaggc aactatgcgc ctcatgcagc aatcatggcc 1510801 ggcggtatgg ttcctccgct tggtatcgca cttgcaacaa ccattttcag aaacaaattc 1510861 actcagcgtg accgtgaagc tggtattaca tgctatttca tgggagctgc tttcgtaaca 1510921 gagggagcga tcccatttgc tgcggctgat ccgcttcgcg tcataccagc tgctgtagtc 1510981 ggtgcagctg ttgccggcgg attaactgaa ttcttccgag taacgcttcc ggcgcctcat 1511041 ggaggagtat tcgtagcttt cattacaaac catccgatgc tttacctttt aagtatcgtg 1511101 atcggtgctg tcgtgatggc aattatcctc ggtatcgtca aaaaacctgt tacagaaaaa 1511161 taagaaaaaa agcgtccttg gttcgaaagg acgctttttc ttatccggcc ggcagggagc 1511221 gcggttaagt tatgtatttt attctttttt atgataaagt aaaagaagag aaacaactga 1511281 catagcaatt gtctaggagg aaacactttg accgaggaaa aaaatacgaa tactgagaaa 1511341 acggcgaaga aaaaaaccaa tacgtacctg gaatggggta aagcgattgt catcgctgtt 1511401 ctgctggctc tcctgatccg tcactttttg tttgaaccgt atttagttga aggttcatct 1511461 atgtatccca cattacatga cggagaaagg ctgtttgtga ataaaacagt caactatatc 1511521 ggcgagctga agcgcggaga tatcgttatt atcaacggtg aaacttctaa aatccattat 1511581 gtaaaaagat tgatcggaaa gcctggagaa accgttcaaa tgaaggatga cacgctttat 1511641 ataaacggta aaaaagtagc cgagccttac ttgtctaaaa acaagaagga agcagaaaaa 1511701 cttggtgtca gtctgacagg agactttgga ccggttaagg ttccgaaagg caaatacttt 1511761 gtcatgggag ataaccggct gaattctatg gacagccgaa acgggctggg actgatcgcg 1511821 gaagatcgaa ttgtcggcac atcgaagttt gtctttttcc cgtttaacga aatgcgtcaa 1511881 acaaaataaa aacgccttgc tggcctagga cagcaggcgt ttttattttg aaaaagaagc 1511941 gaccaatgca atgcataaaa ccgtgatgaa cactgaaccg ataatagcca gcacactgaa 1512001 gaaaaggtga acctgtttgt tctcttttcc gcgcttttct aatagccgtt tagaaaaaat 1512061 gtgcgaaaat atgtaaataa gggctatgcc tatatataag ccgatatctt tggcggtaaa 1512121 gcctgttacg gcaaggtaaa agcccgtaaa aaagatcagt aagcaatatt cagtaagtgt 1512181 taaaagcctc aacgtgttcc tccatgagag tgtgtaattt tccaggcgga tgcattctct 1512241 ctctttaatt gtaacacagc tggctggttt gggtgtataa gtgttttctc tctgttttat 1512301 cagggaatca tttctcttgc cctgcattca tggtatactt ttattgatga tagacatgat 1512361 ggaggataat aaatgattgc tgtaaataat gtaagcttgc ggtttgcgga tcgcaagtta 1512421 tttgaagatg ttaatattaa atttacccca ggcaactgct atgggttaat tggtgcaaac 1512481 ggtgccggta aatcaacgtt tctaaaggtg ctgtcaggcg aaatcgagcc tcagacaggc 1512541 gacgtgcata tgagtcctgg cgagcgtctt gccgtcttga agcagaacca ttttgagtac 1512601 gaagagtatg aagtgctgaa agtggtcatt atgggccaca aacgcctgta tgaagtcatg 1512661 caggagaaag acgctattta catgaagcct gatttctcag atgaggatgg gattcgtgct 1512721 gctgagctag aaggtgaatt cgcggaactg aacggttggg aagcggaaag tgaagctgcg 1512781 atcctgttaa aaggccttgg tatctcagaa gatctgcaca caaaaaagat ggcagacctc 1512841 ggcggttcgg agaaggtaaa agttctcttg gcacaggcat tattcggcaa gccggatgtt 1512901 ctgctgctcg atgagccgac gaaccacctg gaccttcagg caattcagtg gcttgaagag 1512961 tttctgatta actttgaaaa cacagttatt gtcgtatccc atgaccgtca ctttttaaat 1513021 aaagtatgta cgcacattgc cgaccttgat tttaacaaaa ttcaaatcta tgtcggaaac 1513081 tatgatttct ggtacgagtc aagccagctg gcgttaaagc tttctcaaga agcgaacaag 1513141 aaaaaagaag agcagattaa acagcttcaa gagtttgtcg ctagattcag cgccaatgcg 1513201 tctaaatcta agcaggctac atcaagaaag aaacttctcg aaaaaatcac gctggatgat 1513261 attaaaccgt cttcccgccg ctatccttat gttaacttca cgccggaacg ggaaatcgga 1513321 aatgatgttc ttcgcgtgga aggcttaaca aaaacaatcg atggcgtaaa ggtgcttgac 1513381 aatgtcagct ttattatgaa tcgagaagat aaaattgctt tcactggccg aaatgaactt 1513441 gctgttacta cgctgtttaa aatcatttcc ggggaaatgg aagctgacag cggaacgttt 1513501 aaatggggtg ttaccacatc tcaagcgtat tttccaaaag acaacagcga atatttcgaa 1513561 ggcagtgatc tgaaccttgt agactggctt cgccaatatt ctccgcacga ccaaagtgag 1513621 agctttttac gcggtttctt aggacgcatg ctgttctctg gagaagaagt ccacaaaaaa 1513681 gcaaatgtac tttccggggg agaaaaggtc cgctgtatgc tgtcgaaagc gatgctttct 1513741 ggcgccaata ttttaatttt ggatgagccg accaaccatt tagacctaga gtccattaca 1513801 gcgctcaata acggcttaat cagctttaaa ggcgctatgc tgtttacttc ccatgaccat 1513861 cagtttgtgc agaccattgc caacagaatt atagaaatta cacctaacgg catcgtcgat 1513921 aagcaaatga gctatgacga gttccttgaa aatgctgatg tgcagaaaaa attgactgaa 1513981 ctatacgccg aataaaaaag cagagatttc tctgcttttt ttgataccta aatgtgaaag 1514041 gagatcacaa catgaaattt ttggttgtcg gagcaggtgg agtaggcggg tatattggcg 1514101 gacggctttc ggagaaagga aatgatgtga catttctcgt gcgccaaaaa cgagctgagc 1514161 agcttaaaaa aaccgggctt gtcatccata gtgaaaaagg gaatgtatca tttcagcccg 1514221 aactaatcag tgccggagaa acagggcaat ttgatgtcgt tatcattgct tctaaagcat 1514281 actcgcttgg tcaagtgata gaggatgtca aaccatttat ccatcaagaa tctgtcatta 1514341 tccctttttt aaatgggtac cgccactatg agcagctatt tgcggcattt tcaaaagaac 1514401 aggtgctggg cggcctgtgt tttatagaaa gtgctttaga caacaaagga gaaattcatc 1514461 atacgagcgc atcgcatcgt tttgtatttg gagaatggaa cggcgagcgt acggagcgga 1514521 taagagcgct tgaagaggca ttttcaggtg tgaaggctga agtcatcatt agcgggcata 1514581 tcgagaagga catttggaaa aagtatctct ttattgcagc gcaagcgggg atcacaacgt 1514641 tatttcaacg accgcttggc ccaatcctcg ccacagaagc cggacgtcac acggcccaaa 1514701 ctcttattgg ggaaatttgc actgttttac gaaaagaagg tgttccggct gatccggctc 1514761 ttgaggaaga gagctttcgt acgatgacca gcatgtctta ccatatgaag tcctccatgc 1514821 ttcgggatat ggaaaacggc caaacgacag aaggcgacca cctgcatgga tttttgattg 1514881 aaaaagcaaa acgtttatct ctcgctgcac cagtattaga aaccgtttat gcgaatctgc 1514941 aaatgtatga agcagaaaaa taaaaaaagg aggcggaaaa gcctcctttt atttacttaa 1515001 aaagcccaat ttccgtttct gaagataggc tctcttttcc cgtctgccgt aattccgtca 1515061 atattcatat ccttagaacc gatcataaag tccacgtgtg taatgctttc atttaggcct 1515121 tctttgacaa gctcttcacg agacatctgc tttccgcctt caatattaaa ggcataggcg 1515181 cttccgatcg ccaaatgatt tgacgcgttt tcatcaaaca gcgtgttata gaaaagaatg 1515241 tttgattgtg atataggcga atcgtaagga acaagtgcca cttcacctaa atagtgagaa 1515301 ccttcatctg tttccaccag ttcttttaaa atatcctcac ctttttcagc tttaatgtcg 1515361 actatacggc cattttcaaa cgtcagggtg aaattttcaa taatatttcc gccgtagctt 1515421 aatggttttg tgcttgatac cactccgtca accccgtctt tttgcggcag cgtgaacact 1515481 tcttctgtcg gcatattggc cataaactca tggccacttt cattcacgct tcccgcacct 1515541 gcccaaacat gcttcctagg cagcttaatt gttagatcag ttccttctgc ttgataatgt 1515601 aaggcagcgt aatgtctctc gttcaaatgg tcaacttttt catgaagatt ttggtcatga 1515661 ttgatccacg cctgaaccgg gttgtcttca tttacgcgcg tcgctttaaa aatttcttcc 1515721 cacagaaggt ggatcgcttc ctcctctgat ttgccaggaa acaccttgtg agcccagcct 1515781 gctgatgccg cacctacgac agtccagctg actttgtctg attgaatata ttgtctgtat 1515841 gtatgtaatg ctttgcctgc tgctttttgg aatgccgcaa tccgtttgga atctatacct 1515901 tttagcaagt ctgggttcga cgacacaaca gaaatgaaag cagctccatt tttggcaagc 1515961 tcttctctgc cttttgcttc ccattcagga tattcttcaa atgcttcaaa cggcgcaagt 1516021 tcgtatttta atttggcgac ttcgtcatcc tgccaattca cggtgacgtt ttttgcgccc 1516081 ttttcatatg cgtgttttac aattaaacgg acaaaatccc gaacgtctgt tgaagcattt 1516141 acgactacat actggccttt ttggacatta acgccgactt ctaccgccag ctgtgcatat 1516201 gtatttaatt tctgtgaaaa tgaatccatg aatcattcct ccaagctttt ttctcatcat 1516261 atcaaatatg atcctataaa ggaaagaagg agcccaaagt gaaaaaccca aaacgacacg 1516321 tcttgggttt tttcaatatt atggatgatt cagttttaca gtgccgcctg caggcgaatg 1516381 gggcatattt gccaaagaaa tgctcatgcc tccaagaata attccgctta aaatggctgc 1516441 gatcgctact cttcttccta aatctcttag catctgtttc ctccttaacg tttctccatt 1516501 tcccacaata tgaaggaagt gaggaaaaaa gaagcaagaa atttgccgcg tgtgagaatt 1516561 ttgcgggtaa agactattta attgcctttt gcagcttatc aatcacttct aaagaacggc 1516621 ctgtgccgat tgctacagat tcaagcgggt tttgcgccac gtgtacaggc acgacaatct 1516681 cttctgtgag ccattcttta attccattaa ggagcgcgcc gccgcctgtt aaaataacgc 1516741 cgcgatcaac aatatctccg ctcaattcag gcggacagtc ctcaagtgtc gctctgatgg 1516801 cttcaagaat atgcaggagg gattcacgca ttgcatcttg aatttcgttg gattgaagca 1516861 taatggtttt tggaagacct gtcacgaggt cacgtccccg aatttccatt gcctctggta 1516921 tatgttcaat cagagcatgg ccaatttcca tttttacctg ctcagctgtg cgttcgccga 1516981 tcagcaaatt gtatttttta cggacgaaag aaacgatatc ctcatcaagc tggtctccgc 1517041 cgatcctgat agaatggcag gaaacaacgc caccgaagga aataatagcg acctctgtcg 1517101 tccctccgcc gatatctact accacattgg caaccggctc atcaaccggt aaatccgctc 1517161 cgatggcggc tgcaactggc tcttcgatta aatgaacgtt tttcgcgccg caatttttca 1517221 ccgcatcact gatggcgcgg cgttctactg ctgttgagcc tgatggtgtg caaacgacta 1517281 cgttcggttt tctgaacgac atgccgatgc tttttgcggc ttttttcata atgtgcttta 1517341 gcaggtcagt tgtcatatca tagtctgcga tcacgccatc tttcatcggt ctgacagcga 1517401 caatttttcc cggtgtttta ccgatcatgt ttttcgcgtc agctccgatt gcaagcactg 1517461 cttttgtcgt cgtatccact gcgacaacag atggttcatt taggataatc cctttatttt 1517521 tgctgtaaac aagtatatta gctgttccta agtcaatccc gatttcagtt gattgaaaca 1517581 tgttttcacc caatctctat cctaatttaa tatgattcta catttaaagt ttctcagaaa 1517641 tactgcgatt tttgggggtg tgcgtcggta aagaaatgtt tttgtaaaaa atcaaggaac 1517701 tgtgtaacag aagtaataca tttttcggtt ttatggaaaa aatatcttgt aattcttata 1517761 gaaagcggga aactttttca aagtttcatt cgtctacgat atattgaggt acatccttaa 1517821 aacattacat gagaaaagaa acatttaaag gaagaagggt ttttatgaaa tcaataggtg 1517881 ttgtgagaaa agtagatgaa ttaggccgca ttgtcatgcc gattgagttg agacgggcat 1517941 tggatattgc cataaaagac agcattgagt tttttgttga cggagataaa attatcttga 1518001 aaaagtacaa acctcatggc gtttgtttaa tgactggaga aatcacttca gaaaataaag 1518061 aatacggcaa cggtaaaatt acgctaagcc ctgagggtgc acagctgctt ctcgaagaaa 1518121 ttcaagccgc tttaaaagaa taaaattatg ctaaaaaagg cggagtgata tcatctccgc 1518181 cttttttgcg tgccaatttt tgattaccgc cgcctaagat aagacatcaa gatatttggt 1518241 aatgaatgat ttgggatact ttacatattt tactcaatta tttgtcgaag aatggtacaa 1518301 taagtagaga aacacaagcg gcaggtggtc atatgagaaa atatcaagct cgtatcattt 1518361 ccatcatttt ggcaatgatt tttataatgt tttgggatta tttattttat tttataggca 1518421 aaaacccgat taattggcct gttgatattg tgtatactgc agtcacgctg gtaagtgtct 1518481 ggatgttggc ttattatatt gatgagaaac agcagctggt taagaaaatg aaggataacg 1518541 aatggaagta taaacagctt tctgaagaaa aaaaccgcat catggataat ttgcaggaaa 1518601 tcgtatttca aacgaatgca aaaggtgaaa ttacatattt aaaccaagcg tgggcatcta 1518661 taaccgggtt ttcaatcagt gaatgtatgg gaacaatgta taacgattac ttcataaaag 1518721 aaaagcacgt agccgaccac attaacaccc aaatccaaaa caaagcgtct tctggcatgt 1518781 ttacggcaaa atacgtgaca aaaaacggca cgattttttg gggagaagtt cattataaac 1518841 tttactatga ccgggatgac caatttacag gcagcctggg tacaatgtca gatatcactg 1518901 agcggaaaga ggctgaagat gagctcattg agattaatga acggctggcg agggaatccc 1518961 agaaactatc aatcacaagt gaacttgccg caggtattgc tcatgaggtc agaaaccctt 1519021 taacatctgt cagcggtttc ctccagatta tgaaaacaca atatccggac agaaaagact 1519081 attttgacat catcttttca gagattaaaa gaatcgattt agtgctcagc gagctgctgc 1519141 tgcttgcaaa accgcaggca atcacattta aaacacacca gcttaatgag atcttgaaac 1519201 aagtcacgac attgcttgat accaatgcaa ttctgtccaa tatcgtcata gagaaaaatt 1519261 tcaaagagac agatggctgt atgattaatg gagacgaaaa tcagctgaag caggtcttta 1519321 tcaacatcat taaaaacgga attgaggcaa tgccaaaggg cggtgtcgta accatttcaa 1519381 ctgctaaaac cgcctctcat gcagtgataa gcgtaaagga tgaaggaaac ggcatgccgc 1519441 aggaaaagct gaagcagatt ggcaaacctt tttattcaac aaaagaaaag ggcactggac 1519501 tgggacttcc catttgtttg agaatcctga aggaacatga cggggaattg aaaatcgaaa 1519561 gtgaagctgg aaaaggcagc gtctttcaag tggttttgcc tttaaaatca gacagctgag 1519621 aggagaaaaa taaagtgaac tcgcttctgt ttgtatacgg gacattaaga aagcatgaaa 1519681 aaaaccatca tttgctggca caatcggcat gtatcaatga gcaggcgaga acaaagggaa 1519741 gtttgtttgc tgcaaaagag gggcccacag ttgttttcaa tgatgaagat gaaggctata 1519801 tatatggcga agtatatgaa gcagatgaat tgtgtataca taagctcgat caattttttc 1519861 aaggatatca taaacaaacg gtgtttgtag aaacggatgt cgggattaaa attgcgctta 1519921 tttattttat gaacaaagac gggtgtgccg gttttacgaa aataagcagc ggcgactgga 1519981 aagaacatca gatgatcagc aaatcgaaaa atcccattta ttattttgcc tatggatcat 1520041 gcatggataa tgcccgcttt caaaaagcgg gagtcgatca ctattttcaa gatccagtag 1520101 gaagagctgt tttaaaagga tacacaaccc gcttcacgct aaaaagggaa gacggttcaa 1520161 gagcggacat gttggaagac ggaggaacaa cagaaggcgt tttataccgt atcccttatt 1520221 ctgctctctc ctatctatat aaaagggagg gcgtcgaatc tcttacgtat cggccggcat 1520281 ttgtagacgt tgaagctggc ggaaggcact acaaagactg tttaaccttt ctcgtcctcc 1520341 aaaaagaagc ggaaattgcc ccgcctcagc actatcagat tgaaatcgaa cgcggagcgg 1520401 agctgtattt gtcgcctgag tttactgaaa agctcaagcg gcatatgaat tcgctgccaa 1520461 aaggataaca ctgtaacaaa agaatatgat aaaatttgat caatatcatg tcatataaag 1520521 gagcaccacg atgaaaaaag aatttgcggt aattgggctg ggccgttttg gtggcagtat 1520581 ttgcaaagca ttaagcgaag aaggcgtcga ggttatggca atggatatcg atgaagataa 1520641 agtcaacgag tatgccaaga ttgcatctca cgcagttatc ggtgattcga cagacgaatc 1520701 tgtcctgaaa aatttaggcc tgcgaaattt tgaccacgtt attgtagcaa tcggggaaaa 1520761 tattcaagcg agtattttaa cgacactcat tctgaaagaa cttggcgtcc atacgattac 1520821 agttaaagcg cagaacgatt atcacgaaaa agtgctgtct aaaattggtg cggatcacat 1520881 cgtccacccg gaacgcgata tggcaaaacg aattgcgcat aatatcgtgt ccaacaatgt 1520941 acttgactat ttggagctgt ctgaagagca tagtcttgtt gaaatcgtag ctaacagccg 1521001 cctggctgga aatacgcttc tcgatttaga tattcgcgca aaatacggta ttaacatcgt 1521061 agccataaaa aggggcaagg aagtcatcgt atcaccgctt gcaaccgaag tcatccacca 1521121 agaagatata ctcattgtta ttggatcagt tacagacatc tcccgtttcg aaaaaagagt 1521181 tcttcataca aaatagcagc caaataagcc gtcctcaaag ggcggttttt catattatca 1521241 gaatataaca actttaatga actgagcgtc aatttcttaa aatttcattg actaagcaca 1521301 ggcgttccga tagcatattg taccatataa taaaaaaagg aggggcctat ttgaataaag 1521361 aagcgctagt caataggctg aatgcttcag ccaaaagaca aaaagctgat atcgtcatta 1521421 aaaacggaaa aatcatggac gtatataatc aagaatggat atatgaagat attgcgatta 1521481 cagatggagt tattgtaggc ctcggtgagt atgaaggcga aaatatcatt gatgcagagg 1521541 gacaaatgat tgttccgggt tttattgatg gacatgtaca tattgagtcg tcaatggtta 1521601 caccgattga gttcgctaaa gcagtgttgc ctcatggcgt gacgacggtt gttacagatc 1521661 cgcatgagat cgcgaatgtg tctggtgaaa aagggattga gtttatgctt gaacaagctc 1521721 ggcatacacc gctgaatatc cattttatgc ttccttccag tgtgcctgcc gcaagttttg 1521781 agcgatcagg cgcaattctc aaagctgccg atctcaagcc tttttatgaa gaagaagaag 1521841 tattagggct ggctgaagtt atggattatg tgtcggttca gcaggctgaa aaagacatgg 1521901 ttcagaaact gcttgatgcc cgtgtggcag gaaaaaggat agacggtcat ttagctggtt 1521961 tatcaacaga cctcattaac atttacagaa ccgcatttgt cttaaacgac catgaagtaa 1522021 catcgaagga agaagccctt gatcgtatca gaaggggcat gtatgtcatg atgcgtgaag 1522081 gatcagtcgc caaaaacacg ctcaatgtgc tgccggcggt gaatgaaaag aacgcacgcc 1522141 ggttcttttt ctgtacggat gataagcatg tggatgattt attgtcagag ggaagtgtaa 1522201 accatcaggt gaaaatggcg attcaagccg gacttaatcc gtttttagcc tatcagctag 1522261 gaagcctcaa tgcagccgaa tgctacggat tagatacaaa gggagcgatt gccccgggtt 1522321 ttgacgctga tttgcttttt gtatctgatc tggaaaatgt cactgtcaca atgacgatgg 1522381 taaaagggca gactgttgct gaagacagca aagcggtcta tcaggatcat gcttcaactg 1522441 cagcaccaga tcaggcactg cttgattctg ttaagcttgc tgctcctctt aacaaacagg 1522501 attttcatat gccaatcgat tcagagcagc agatcaatgt cattcaaatc ataccaaatc 1522561 agcttgaaac acgattagta caagttccgg ctcctgttgc ccgcgaattt gagcctgaca 1522621 ctgagcttga tttgttaaag attgcagttg tcgagcggca taaaggatta aaagaaaccg 1522681 gacttggtgt tgtgaaaggt tttggattca agagcggagc gattgccaca accatttcac 1522741 acgactccca taatattatt gccgtcggaa cgaatgatga ggatatcgcg gcggcagtta 1522801 ataagctgca ggaaattggc ggaggattaa caattataaa aaatggggaa gagctccatt 1522861 cagtaccgct gccgattgca gggttattat ccgaccaatc tgcagagcaa gtgaatcaaa 1522921 gcttgctgac gcttcatgat aaattgtcgt taatcggttt cacaggcgga tttaatccat 1522981 ttttgacatt gtcgttttta gcgttgcctg tcattcctga tattaaaatg acgactacgg 1523041 gattattcga tgtaaaatca tttcaacaca tatcactgca ataaaaagag gcactccctt 1523101 agggagtgcc tcttttttta aacctccata atgatcggca ggatcattgg acggcgcttt 1523161 gttttttcgt acaagaaagg tgcaagcgtg tctgtaattt cgtttttgat ttcagaccat 1523221 tgagtcgttt ttcgttccat tactttttgt aagtgatttg aaatgagctc ttgagcgtcg 1523281 ttgatcaagt caccagattc tctcatgtac acaaatcctc tggaaatcaa atcaggaccc 1523341 gctgaaatct tgaagtcgtc catgtcaatg ctgacaacaa cgatgacaag tccttcttca 1523401 gagagaattc tgcgatcacg aagtacgata ttgccaatat caccgatacc gcttccgtca 1523461 atgtacactg aaccggacgg gatttttcct gcaactgaag cctcatcgcc tttaagtgct 1523521 aatacttcac cattatccat gataaagcag ttttcctctg ggatgccaca atctgttgca 1523581 agtttgacat gcatcttttg cattctgtac tcaccgtgaa tcggcatgaa gaatttaggc 1523641 ttgattaaac gaagcatcag cttctgttct tcctgtccgc cgtgaccgga tgtatggata 1523701 tcgttaagag ggccgtgaat aacctcagca cccgcacgat acagctggtt gattgttcga 1523761 ctcacgctga ttgtgttgcc tgggataggg gatgaagaaa atacgactgt atccccagga 1523821 ttgattgaaa tttggcggtg tgtgccgttt gcaattcttg ataacgccgc cattggttcc 1523881 ccttggcttc ctgtacataa aattgttact ttattagcag gcatacgatt gatttcgtta 1523941 tgctcaataa acgtattttt aggacagtta atataaccga gtgtctgtcc aatttcgata 1524001 gccgattcca tactgcgtcc aaatacggca acttttcttc cattttgtac agcagcttca 1524061 attacctgct gcaagcggtg aatattcgac gcaaatgtgg cgaagataat tcggccgtcc 1524121 accttgcgga aaatgtcatg aatgctttct cctacacggc gctcagacat ggtaaactcc 1524181 ggattttcac tgtttgtgct gtctgaaaga aggcacaaaa cgccttcttt accgatttcg 1524241 gccattttcg ttaagtttgc cggctcgccg actggagtaa agtcgaattt gaaatcccca 1524301 gtatgtacga tgtttccggg cggcgttttt acaacaatgc cgtaggaatc cggaatactg 1524361 tgtgttgttc tgaagaatga cacagccgtt ttgcggaact ttacaatatc atcctcgccg 1524421 ataatgttca gtttcgtctg tctcaataat ccatgctctt caagtttatt ccgaagtaag 1524481 ccgatcgcga gttttccgcc gtatacagga atattcactt gtctgagcag gtatggaata 1524541 ccgccgatgt ggtcttcgtg cccgtgggtg ataaaaagcc ctttaatttt atcttcgttt 1524601 ttgactaaat acgtataatc agggatgacg tagtcaattc cgagcagttc gtcctcggga 1524661 aacttgatcc ccgcatcaat cagtacaatt tcatcctgga attgcaccgc gtacgtattt 1524721 ttaccgattt cgcccaaacc tccgagggcg aaaacagcag tctgatcatt ttttacaaat 1524781 ttcataccgc tcataactcc aatactttaa aattttcgct ctgttgttca tattctaaga 1524841 atgcaccatc aacaggtgta ataaactcaa tattaaattt cttttctttc agctttgttc 1524901 tgacgtcacg ctcagatacg ccttcaatat aaagtgaatc tgtcttttcc cgaacaggta 1524961 cttcgtcagc cttctcttga taaaatacct tataaatcat tccaaatctc tccttaaatg 1525021 ccgtatgtta gactcgctca ttctattata ttcgaaaacg gaatataagg aaagccttga 1525081 gcaaaataag gatctctcaa aaagtgaaag atcccttgtc aggcaattgc tttcttacgg 1525141 agcattccgt tccattgtct tctgagtttc tttcttaatt tacgcagcat tagccagtcc 1525201 ctcctttaat gaaaaatttg tcccagagtt cttttataca aatagtatac ggagattgag 1525261 gaagactttt cgtggttatt aatggaattt aatatgattt ttgaacgaaa ttgtttgctg 1525321 aatgacaatc tttttgtatg atgagggtgg gaattgcaga ccaagacgat aaaggggaag 1525381 ttgcgatgga ttctaaatta atcttttttg atattgacgg cacaatatat gatcatgata 1525441 agaatatacc ggaaagtacg agaaaaaccg tggcggagct tcagcgccaa gggcatcatg 1525501 tgtttattgc cagcggccgg tctccatttt tggttaagcc gattttggag gagctgggca 1525561 tccactcatt tatttcctac aatggacagt ttgttgtctt tgaaaatcaa gtgatttata 1525621 aaaatccgct gcctgaaaat gcaatcaggc gattattaaa gcaggcggat gaaggcaagc 1525681 atcctgttgt gtttatggct gaggacacga tgaaagcgac tgttgcggat cacccccatg 1525741 ttctcgaggg aatcggcagc cttaaaacag attatccaga gaccgatgac cttttttatg 1525801 aaggaaaaga aatttttcag cttcttttat tttgtcagga tgaagaagaa aaagcttatg 1525861 ccgcttttcc tgagtttgat ctagttcgct ggcatgagct atcgactgat gttctgccgc 1525921 acggaggttc gaaggcagaa ggaatcaaaa aagtgattga gcgtcttccg tttgatatcg 1525981 gcgatacata tgctttcggc gacggattaa atgatttgca aatgattgaa tacgttggga 1526041 caggcgttgc tatgggaaat gctgttcccg aactgaaaga aatcgcggac tttgtaacaa 1526101 aaccggtgga cgaggatgga attgcatacg ctgtcaaaga attgggcctt ttaaaataaa 1526161 gaaacggctg gcattgtgcc agccgttttc tcttttagcg ctcaattgcg attgcatttt 1526221 caggttcttt gaaaggattt tccttatcaa tatgatcata gaacataacg ccgttcaaat 1526281 gatcgatctc atgctgaaac acaatagccg gaaatccttt taaacgaata tcaatatttt 1526341 cgccttctag tgttgttcct tttactctga tgcgagcata gcggggaaca taaccgggaa 1526401 tcgcttcatc cacagagagg cagccctcgc cgcttgttaa gtagcttttt tcaactgaat 1526461 ggctgacgat cttaggatta aacagagcat agctgtataa tttaccggaa gcatcttccg 1526521 catgaacggc gatcattcgt tttttgatat taatttgagg agctgcgagt cctacgccag 1526581 ggcgcagctt gtatttttcg gctaattctg gattttggct gtttttaaca aattcgatca 1526641 tgtcggccag ctgctgtttt tctgcatcag ttggaggcag ctcaacaggt tcggcagtct 1526701 ctctgagggc tggatggccg tcacgtacga tgttttccat agtaatcaag aaacttcact 1526761 cctaaagctt aatatgtaaa ttatatcgga tttcttcaca aaggtgcaac gaaacgaatg 1526821 accagccgta tatggctggt caatttcatg ctgtgtggtt agcaacagcc tccacctaaa 1526881 taagcagctc cgacaatgat taacagaatg aataaaacaa cgattagcgc aaaggtgcgg 1526941 ccgtagccat atccgcagcc accatatccg taaccaccat aactgcagca gcctccgccg 1527001 taaccatatc catacatatt acataacctc ctcttttaat tacgccagag cctttataag 1527061 taggcatagc gtctaatata acctatgtaa aaacaaaaaa gttgtatggt catctgtcct 1527121 gatttttcac ttttttgatt taatttcagt attgcattta tacagcacgg ctattgccaa 1527181 atgtccccat ggattctata gtagaaattg tcaagattgg gggatttaac gtgaaagacg 1527241 ctataaaacg gcggcctgga atcaagatcg gagctttttg tgccatggca ctgatattaa 1527301 caggatgcat gggacaggac ccggttgatt cacttcatca ttcattagaa aaagccgcgg 1527361 aatcggaaaa gccgtttcaa gaagaacaaa acacactcaa agaattagag gccaaagaaa 1527421 atcagcttta cgatagtgtt atgaagctca atatggatga ttataaaaaa attgttgctt 1527481 tatctaataa ggcgcttgaa aatgtcagca agcgcgaaga acacctaaag cttgaaaatg 1527541 acagcatgaa aaaatcggaa acagaatttg aggaagcaaa aacgtcagcg gaacatatta 1527601 aggaaaaaga cataaaagaa aaggccgatg ccgcagcaaa ccatatggag aaaagatata 1527661 catcatatgg cactatgtat aaagagtata aaaaagcgct tgagcttaat aaaaaactgt 1527721 atatgcagct gaaagacaaa gatttgacaa gagatgatct ggatcagcag atcgataaag 1527781 tcaatgcttc ttatgaaaag atccttaaat atagcggaga atttaatgaa caaaccgaaa 1527841 aatataataa agcccgggaa gatttatatg atgctgcagg ctatcgtgtg aaaaagagct 1527901 gactcgatca gctctttttt tgaatgaaat gcgattcgga tttcgttcaa aattttcatt 1527961 tctattgtag tacagcatag taaggtatac tagtacagtt ttgggtgcgg ttggcatctg 1528021 tttttttgat gaaaatgtaa agcgaataca tttattgaaa atcagcgatg aaaacgattg 1528081 acggttcttc tttatttggt gtaaactaat ccatgttaag cggtgttgta ttagtttttt 1528141 acaacttcga aataatacag ttcaaagcag agtgtaacta tcctacataa aaggttttgg 1528201 caaactgggg atcggctaaa atataatacg acttactgct gatactttag ggtaccctaa 1528261 gtttgtatgt ataaaaggaa tgcacgtcta atgactgttt aaaagaaagg aagaggtgac 1528321 ttagtatggc tgcaaaaacg aaaaaagcta tcgttgacag taagaagcaa tttgatgcca 1528381 ttaaaaagca gttcgaaacg ttccaaattt taaatgaaaa gggagaagtc gtgaatgaag 1528441 cggcgatgcc tgatttaact gatgatcaat taaaagagct aatgcgccgc atggtattta 1528501 cgcgtgtgct tgaccaacgc tctatctcat taaaccgtca aggacgtctc ggattttacg 1528561 ctcctactgc gggtcaagaa gcttctcaga ttgcaacgca tttcgcgctt gaaaaagaag 1528621 actttgttct tcctggatac cgtgatgtgc ctcagttaat ttggcacggc cttccattat 1528681 atcaagcgtt tcttttctct cgcggacatt tcagaggaaa ccaaatgcct gatgatgtga 1528741 atgccctttc tccacaaatc attatcggtg ctcaatacat tcaaactgcc ggtgttgcgc 1528801 taggtcttaa aaaacgcggt aagaaagctg tcgcaatcac ttacactggt gacggcggag 1528861 cttctcaagg ggacttctac gaaggaatta actttgccgg agcttataaa gcacctgcaa 1528921 tcttcgtggt gcaaaacaac cgttacgcga tttcaactcc tgttgaaaaa caatctgcag 1528981 ctgaaacaat tgcacaaaaa gctgtagctg ccggtattgt cggcgtacaa gtagacggaa 1529041 tggatccgct tgctgtatac gcagcaactg ctgaagcacg cgagcgcgca atcaacggcg 1529101 aaggtccaac actaattgaa acacttacat tccgttatgg cccgcacaca atggctggtg 1529161 acgatcctac taaatatcgt acaaaagaaa tcgaaaatga gtgggaacaa aaagatccgc 1529221 ttgtacgttt ccgtgcgttc cttgaaaaca aaggcttatg gtctgaagaa gaagaagcaa 1529281 aagtgattga ggatgcgaaa gaagaaatta agcaagcgat caaaaaagct gatgctgaac 1529341 cgaagcaaaa agtaactgat ttaatgaaaa tcatgtacga aaaaatgcct cacaaccttg 1529401 aggagcaatt tgaaatttat acacagaagg agtcgaagta agccatggcg caaatgacaa 1529461 tgattcaagc aatcacggat gcgttacgca cagaactgaa aaatgacgaa aatgtcttag 1529521 ttttcggaga agacgttggt gtaaacggcg gcgtattccg tgcgacagaa ggattgcaaa 1529581 aagaattcgg tgaagaccgt gtgtttgaca cgccacttgc tgaatctggt atcggcggtc 1529641 ttgcccttgg tttaggctta aacggcttcc gtccggtaat ggaaatccaa ttcttcggat 1529701 ttgtttatga agtaatggat tcagtttctg gccaaatggc tcgtatgcgc taccgttctg 1529761 gcggacgctg gacttcacct gtaacaattc gttctccatt cggcggcggt gttcatactc 1529821 ctgaacttca cgctgacagc ttggaaggtc ttgttgcaca acagcctggt atcaaagttg 1529881 ttattccatc aactccttac gatgccaaag gacttttaat ttctgcgatc agagacaatg 1529941 atcctgttgt cttcttagag catatgaagc tttaccgttc tttccgtcag gaagttcctg 1530001 aagaagaata cacaattgag cttggaaaag ctgacgtgaa acgtgaaggt actgatcttt 1530061 caatcatcac ttacggcgca atggttcatg aatcattaaa agctgctgat gagcttgaaa 1530121 aagacggcat ttctgctgaa gttgtcgacc ttcgtacagt aagcccactt gatatcgata 1530181 caattatcgc ctctgtagaa aaaacaggac gcgcgattgt cgttcaagag gcacaaaaac 1530241 aagccggtat tgctgcaaac gtagtagcag aaattaatga ccgtgcgatc ctgagcttgg 1530301 aagcacctgt acttcgcgtt gcagcgccag atacagtatt tcctttctct caagcggaga 1530361 gcgtatggct tccaaaccat aaagacgttc ttgaaacagc aagaaaagtg cttgaatttt 1530421 aatcaaactg cataatcgag agggaagatg aacgttttcc ctctattata tatctgtttt 1530481 caatgcttac gatgtaaact ttaaaattgc ttaatcaaac taggaggtcg agaactgtgg 1530541 catttgaatt taaacttcca gatatcgggg aaggtatcca cgaaggcgaa atcgtaaaat 1530601 ggtttgtcaa gcctaacgac gaggtagacg aagatgatgt actggctgaa gtccaaaatg 1530661 ataaagcagt agtagaaatt ccttcacctg ttaaaggaaa agtattagaa ttaaaagttg 1530721 aagagggaac ggttgcaact gttggacaaa cgattattac gtttgatgca cctggttacg 1530781 aagatcttca atttaaaggc agcgacgagt ctgacgatgc gaaaactgaa gcacaagttc 1530841 agtcaactgc agaagctgga caagacgttg cgaaagaaga gcaagctcaa gagcctgcaa 1530901 aagctactgg cgcaggacag caggatcaag ctgaagttga cccgaacaaa cgcgtgatcg 1530961 ctatgccttc cgtacgtaaa tatgcacgtg aaaaaggtgt agacatccgt aaggttactg 1531021 gttcaggcaa caacggacgt gttgtaaaag aagatatcga cagctttgta aacggaggag 1531081 cgcaagaagc tgcaccgcaa gaaacagctg caccacaaga aacagctgct aaaccggctg 1531141 ctgcaccagc tccagagggc gaattcccag aaacacgcga aaaaatgagc ggtatccgta 1531201 aagcaattgc aaaagcgatg gttaactcta aacacactgc tcctcacgta acgttaatgg 1531261 acgaagtgga cgtaacaaac cttgttgcac atcgtaaaca gttcaaacag gttgctgctg 1531321 atcaaggaat caagctgact tacttgcctt acgttgtaaa agctcttaca tctgcactga 1531381 aaaaattccc tgttttaaac acgtcaattg acgataaaac agatgaagtc atccaaaaac 1531441 attacttcaa catcggtatc gctgctgaca ctgaaaaagg cttgcttgta ccggttgtga 1531501 aaaatgcaga tcgtaaatct gtctttgaaa tttctgatga aatcaatggc cttgcaacaa 1531561 aagctcgtga aggcaagctt gctccagctg aaatgaaagg cgcatcttgc acaattacaa 1531621 acatcggttc tgccggcgga caatggttca ctccggttat caaccatcca gaagttgcga 1531681 ttcttggtat cggacgcatt gcagaaaaag cgattgttcg tgatggcgaa atcgtagcag 1531741 ctccagtctt agctctttct ctcagcttcg accaccgtat gatcgacgga gcaactgcgc 1531801 aaaatgcatt aaatcacatc aagcgtttac tgaacgatcc acaattaatt ttaatggagg 1531861 cgtaatgtta tggtagtagg agatttccct attgaaacag atactcttgt aattggtgcg 1531921 ggacctggcg gctatgtagc tgccatccgc gctgcacagc ttggacaaaa agtaacagtc 1531981 gttgaaaaag caactcttgg aggcgtttgt ctgaacgttg gatgtatccc ttcaaaagcg 1532041 ctgatcaatg caggtcaccg ttatgagaat gcaaaacatt ctgatgacat gggaatcact 1532101 gctgagaatg taacagttga tttcacaaaa gttcaagaat ggaaagcttc tgttgtcaac 1532161 aagcttactg gcggtgtagc aggtcttctt aaaggcaaca aagtagatgt tgtaaaaggt 1532221 gaagcttact ttgtagacag caattcagtt cgtgttatgg atgagaactc tgctcaaaca 1532281 tacacgttta aaaacgcaat cattgctact ggttctcgtc ctatcgaatt gccaaacttc 1532341 aaatatagtg agcgtgtcct gaattcaact ggcgctttgg ctcttaaaga aattcctaaa 1532401 aagctcgttg ttatcggcgg cggatacatc ggaactgaac ttggaactgc gtatgctaac 1532461 ttcggtactg aacttgttat tcttgaaggc ggagatgaaa ttcttcctgg cttcgaaaaa 1532521 caaatgagtt ctctcgttac acgcagactg aagaaaaaag gcaacgttga aatccataca 1532581 aacgcgatgg ctaaaggcgt tgaagaaaga ccagacggcg taacagttac tttcgaagta 1532641 aaaggcgaag aaaaaactgt tgatgctgat tacgtattga ttacagtagg acgccgtcca 1532701 aacactgatg agcttggtct tgagcaagtc ggtatcgaaa tgacggaccg cggtatcgtg 1532761 aaaactgaca aacagtgccg cacaaacgta cctaacattt atgcaatcgg tgatatcatc 1532821 gaaggaccgc cgcttgctca taaagcatct tacgaaggta aaatcgctgc agaagctatc 1532881 gctggagagc ctgcagaaat cgattacctt ggtattcctg cggttgtttt ctctgagcct 1532941 gaacttgcat cagttggtta cactgaagca caggcgaaag aagaaggtct tgacattgtt 1533001 gctgctaaat tcccatttgc agcaaacggc cgcgcgcttt ctcttaacga aacagacggc 1533061 ttcatgaagc tgatcactcg taaagaggac ggtcttgtga tcggtgcgca aatcgccgga 1533121 gcaagtgctt ctgatatgat ttctgaatta agcttagcga ttgaaggcgg catgactgct 1533181 gaagatatcg caatgacaat tcacgctcac ccaacattgg gcgaaatcac aatggaagct 1533241 gctgaagtgg caatcggaag tccgattcac atcgtaaaat aattttcata tcaaaaacag 1533301 ccccgctttg agcgagggct gtttttttat tttgacagca catgctgtaa tggtttaatg 1533361 atgtcttctt tctttttcac acatccctcg attttcacca cgacatggcg ctgatcaaca 1533421 accataaggg tagggacagt ttcaatctca tcttcccagc cttctttttt atcatagacc 1533481 ttcattttat ctatttgctc gggataatct ttttctaaat caagcagtgc atcgtaataa 1533541 ggcgcttcct ggtctatttg gttctcatca gaaaaaaaca ggatttgtgt atgatgaatg 1533601 ttgtcaatcc ggcttttttt catcggattg atggtggaaa gcgtacagcc cgataaagca 1533661 aatactatta tcagcatggg gaataccgcg cgatatcgca tctatcttct cctctgtata 1533721 aacagtagtt aactagcttt agtttatcac gagagacggc ttaatctgct tcttgttacc 1533781 taattgttat ataattgaaa ccgtttttaa agtgagatta catattatat caatcgttta 1533841 aaatagcaac ctggggtata ttgaattttt tgctgcattc ttggatgaaa gttcaagaaa 1533901 acgtgcaatt acattatgtg ctgtggcata tatatcgagt aaagcttctg tatgaagaag 1533961 atattgtatg atggaaaatg gaaaaacaag gtgaatatga tgatatgaaa taaaatgtgt 1534021 tatacagttt gttgttgaca ttttaaatgt gacatattaa tataataaca acaaaagaaa 1534081 ttaagcgttt tcaaatttca aagaaatggg gaataagaga tgggtacgat tgtttgccaa 1534141 gattgcaacg aagccattca ttactttgaa gatgagaaag tgacaacatt atatggaact 1534201 tgctgcggac aatgtcaatg tcctgttgat gaagagtaaa aaaaagcatg cggcttaaag 1534261 ccgcatgctt tttatttttt attgaattgc tttttgttct ttgatgaccc ggatcatatg 1534321 taaagtcgag tcctcaggtc cttgaacagg gaggcctgcg tcaaggtttt taaaaatgta 1534381 gctgatgttt tcttctgtaa taatttctcc tgggatgaag attggaatac caggcggata 1534441 taccatgaca aattcagcaa taatccgtcc ggatgcttct tttaatggga tgacttccgt 1534501 atttgcatag aaagcatcac gcggagtcat tgccaataaa ggtatttctg gaagcagaac 1534561 ctcagtttgc tgatgtgtta catcttgttc tgacatttgc tgtgcgatct cagttaaagc 1534621 ctctacaagc cggtctgcat cattttggct gtcaccagga gtgaaaatac acaaaatatt 1534681 gtacagatca gaaagctcca cctcaatatt aaaggattca cgaagccatt tttccacgtc 1534741 atgtcctgtc aggccaagac ttttcacaga gataatcaat tttgtcggat catagctgta 1534801 agctgctttc gacccaagaa tctcagaacc gacacaataa atgccttcaa tctgattgag 1534861 gcgatctctc gtctgattgg caagcttgag tgtttcctca gcaagctggc ggccttctgt 1534921 tgcaaggcgt tttctggcaa catccaaaga agcgagaagc aagtaagaag ttgacgtagt 1534981 tgtcagcatg ctcaggatgg attgcactct gtctttagat acaaggcctt ctctcatgtt 1535041 taaaatagag ctttgtgtca gtgatccgcc cagcttgtgt acacttgtcg ctgctatgtc 1535101 cgctcctgcc tgcatagccg atagcggcaa ttcgtcgtga aaatgaatgt gaacgccgtg 1535161 tgcttcatcc acaagcactg gcacatcaaa cgaatgagcg agttctacga tgctttttaa 1535221 gtcggctgca acaccgaaat atgtcgggtt gatgacgaga agcccttttg catccggatg 1535281 ctcggtaagc gcccgtttag cagattcaag tgtaattccg tgggagatgc ccaattcatt 1535341 gtcaatttca ggatgaataa aaattggaac cgctccggaa aatacaatag ctgtcataat 1535401 tgatttatga acatttcttg gaataataat tttatcacca ggtccgcaaa cagccattac 1535461 cattgtcata atggcgccgc ttgttccttg aacagaaaaa aatgtatgat ccgctccaaa 1535521 tgcttcagca gccagatctt gtgcttgttt aataatgcct tttggcgcgt gcagatcgtc 1535581 taatggttca atattaatca aatctatgct taacgcgttt tcaccgataa attgtctgaa 1535641 ttctgggtcc attcctgccc cttttttatg gccgggaatg tggaattgaa caggctgtct 1535701 gcttgcatgc tttttcagtc ctgtgtataa gggtgtttca tgttgcgaca attgttttcc 1535761 cacctttgta atcataccta tgcataatag tgtgtattaa aatcagtttc tcaaccgttt 1535821 tttagacgta aaacaaatga attatattat gaacttgaaa gaatgtaaag aacaatttat 1535881 gatcaaatga agatgctttc tcttaaggga agtaaatcta caaggagtga agaaaatgga 1535941 gtatcaatat ccgatgaatg aagattggac aaccgaagaa gcagtggatg tgattgcatt 1536001 tttccagcag gttgagcttg catatgaaaa aggggcggat cgtgaagaac tgcttaaagc 1536061 ttaccgccgt ttcaaggaaa ttgtaccggg gaaggccgaa gaaaaaaagc tatgcggcga 1536121 gtttgaggaa caaagtacat attctcctta tcgcacggtc aaacaggcga gagaatctga 1536181 tcacgcgaag attaagatgt aagaaaaaga gccgggggat atcccggctc ttttttatgc 1536241 ttgtgttact ttttgggtga gacggtacag aaaagcaagc tgtttaaagg catcgtcgat 1536301 acgctgaagg aattcctggt tattcatatt cagcacttct tctttttgga gctggatgcc 1536361 gcataacagc tcggctttct ttacagtctg caaacgctca aacagtgtct tcagctgttc 1536421 cttgtccatt tcagactgtt tatgtactcc cggttttgtg tgatctgcag accaaacgaa 1536481 gctgtcaggg atatttttcg taatggtttc ttggttcact tcaagcaatt tgccgtattc 1536541 ttctttgata ggggattcat aaataatcgc gaaccataca aagacgtggc tttcccataa 1536601 accaatttgg aaatgcggca gttttttata gcctcttttg ctgtttgcga acgccaccca 1536661 gctgtcagcc gggggattga cggatcttct tgcgtgcttt gccacatgcg gaaacatttc 1536721 atctccggtt aaagctgata aagttggggc aaaatgttcg cctagagctg taagcttcgg 1536781 acggaccgtc tcttttaata cttccatgcg cgcgtctaag ccttctattg taaatgtgtt 1536841 aaagtcttct tcagtgaaac gcatttgtgt catgattttc ctccttcatg ctaagtatac 1536901 atattttatc acagttcata cgagcttcaa aaagattgag cgcgtttgaa gtaaggagaa 1536961 atgtggtaat aaacgagtag gtaaacacac aattttcaga atcatgttgc gcgtaaatag 1537021 aacaatcata cgatataaga agtaatcatt gttgaatggc aaaatgggat gcttttttac 1537081 aaacaaatga tctctggaag gggcgaaaga caatgaggca agttgtaaaa gagggattta 1537141 aggaagagaa aaacaatcgt gttgctgtct ggagactaga ggttgattat gaattggcaa 1537201 ccctatatga agcaatgcag aaagaaaatg aagagcagat tgaacaaagc aaaaacaaac 1537261 ttgagcgact tagaaaagaa tggattcgtc ttaacgggta aaaaagcgat agtgaaaacg 1537321 aaccgcatga atggttcgtt tttacgtgag aagggatatt tttcattttc cttgcttttt 1537381 cattgccgtt atcagtatcc tataaaataa aaggtctaca tagaagagag gtacgaacga 1537441 atgacaaatt ggacggaaat cgatgagatt gcaaagaaat ggataagaga agcaggcgcg 1537501 agaattacac aatccatgca tgaaagcctg acaattgaaa cgaaatcaaa tccgaatgat 1537561 ttagtcacca atattgacaa agaaaccgaa aagtttttca ttgatcgaat tcaagaaaca 1537621 tttccgggac atcggatact cggtgaagag gggcaaggag acaaaatcca ctcacttgag 1537681 ggagtcgtat ggattattga tccgattgat gggacgatga attttgtgca ccagcaaaga 1537741 aattttgcga tttccattgg gatttttgaa aacggtgaag gtaaaatcgg tttaatttat 1537801 gatgtggtgc acgatgagtt gtatcacgca tttagcggca gaggagctta tatgaatgaa 1537861 acgaagctgg ctccattaaa agaaaccgtc attgaagaag cgattcttgc cattaatgca 1537921 acatgggtaa cggaaaacag aagaattgat caaagtgtgt tagcgccact tgtgaaaaga 1537981 gtcagaggca cacgctccta cggttctgcc gctttagagc tggcaaatgt cgcggcagga 1538041 agaatagatg cttacatcac gatgcggctt gcgccatggg actacgcagc cggctgtgtg 1538101 ctgttaaatg aagtaggagg cacctatacg accattgaag gagagccgtt taccttttta 1538161 gaaaaccaca gtgtgctagc cggaaaccca tctatacata aaacgatatt tgaagagtat 1538221 cttcatgctc ggaagtaggc catttgagca ggatgatctc agcttgttag aaaagctcgc 1538281 ggaggctcat cctgtatgga aagaggagga gtttggagat aaagatgcag aagactatat 1538341 catttcctac tccatgtaca acggttcatg gcttgtatgg gaaaaagacg gtatgcctgt 1538401 tgccgtcagc taccatctcg agtggtctcc ttcaaacggt aagccgtggc tcggaacggt 1538461 cctgattgac ccggctgaag aaaaaaaggg acatgcgaag atgatcattg aacagatcag 1538521 caaattgctt agagcgaaac ataaagcgat gtttgcggga gttcccattg agcgcaggga 1538581 atggatactg tttttaagcc aatgcggctt tgaacagctg aaaacggaaa aagatgagaa 1538641 aggcaaatca tttatgatct tggtgaagcc tttagcagaa gctgccgtat gataatggca 1538701 gcttatttgc tgcatgcggg ttcaataaaa agcctctcaa acattgagag gcttctgatg 1538761 atttgaaaat tattttttta ccgcatgaat ataatgaatc gtttcaaacg ctgacaaatt 1538821 gtcttttcga ttactaaaga aaaggtcatt gatgtcgtct ggtgatagat gttcatagat 1538881 cagtaaacca gatgactcta acagatgttc aatctcttga taagtgaaac atgatttcat 1538941 cggttccccg cttgcggcag ccatcttcac catatgttca actcgattcg acgtcccttt 1539001 tgctgtaaaa agtgtttcgt ccgcataatc aaaaacaata gagcttccag gcgggacatg 1539061 agaaaataaa ttgctgatca agcttgcatt ttcttcccgt gttacataat aagacactcc 1539121 gagaaggctg aagaatgttt ttgtgttttt aaatccttca tctaagagag gatcatacga 1539181 aaacgttttg gtgaaatcca taggaacaaa atgaagatga cccggaattg tcagatttgc 1539241 atccttcagc ttattttttt tcaattgctg tgtggccgga tgatcaacct cgaaaacctg 1539301 taagctgttt tctaattctg gatgccgaaa gcagaaagta tccagtcccg ctccaagaat 1539361 gacatactgt tttgccccca ggattaattc gttgtgcaag actttttcac aataagaagc 1539421 acgtgctagg ggcgttggag acagctggat ttgtgcaacc cattttaata ttttttcagg 1539481 atcattttga agacgttcgg cgatctcttt gttgaaaaac gatatttctt gaatcatatt 1539541 tttactgatg tcgataaact ctttttcgtt aatgagatct tttgcgataa aatcatcaaa 1539601 aataagaggt gtgtcatatc ggctgtgata tgcacgggca aaagctgaaa ttagagacgt 1539661 taagctggac tcatttttcc tcatgaaatg atcctccaca aaaaataaga ttcccctggc 1539721 caggagaatc ttattataca tacaaatata ttaatagtaa attttagcat aaataaattt 1539781 ttttgtcaat gtttttgctc ttaactggac gcgcgatcct tcacatagcc acgtgacctg 1539841 tagcagaatt cgtctatcaa ttatgtggac tgaatcatta gcttttataa aatgcgcact 1539901 tgcggctgca tccctcttta tgcaaatcag gagcggtttt ctgtctcatg gcagcatctt 1539961 ttcgtcgttt cagctgagag agaaatcaag atatgtaaca ataaaagcct gagggatctc 1540021 aggcttttcc taatattaca atccaacagc attccaggct gcttcaactt tagcggcatc 1540081 agttgagccg tagaggtcac gggcagactg aatgagagct gccttggcat ctttgaacgt 1540141 ggaagaaggc gtgaggtacg ttgttaacgc acggtaatag atttgctgtg atttagatac 1540201 accaagtttt gtgatggtgt tgtaagcggc tttgtttgga attccgctgt ttgtgtgtac 1540261 accgccataa tcgccttcat ctgtgtttgg aaggtttcgg taattggcgt aattgtcagg 1540321 ctggttgtat tttgtagggt tggacaggct gcgaagagca ggctggctga ccgtaatgtc 1540381 ttcaccgatg tcccagtctt ctgtatcgtt aaaatacccg aatacgtcag agaaagactc 1540441 gtttaatgca cctggctgat tttcataaat caagttggct gtttcttggg tgacgccatg 1540501 tgtcatttca tgcgctgtca catctaatga gccggaaagc ggagagaaga atgaaccgtc 1540561 gccatcaccg taaatcatct ggtctcctgt ccatgcagcg ttattgtatt gagtgccgta 1540621 gtgaacggaa gaaacgattt tactgccttt gttatcatag ctgtttcgtt taaagtttga 1540681 ataaaaataa tcgtacactt taccgaggtt atagtgtgcg tcaacggctg cccgctgtga 1540741 tgaagatgta aatgttttcg ttgtgcttga gacaagcgtg cccggaaggc ggctttgtct 1540801 gttttgcaaa tcatatgtga tgatttgggt gcctgttggt tttgaaagat ctcttagaac 1540861 atattttccg ccttcataag agatgttcaa aggaacagtt gcgcccttta gcgttgttcc 1540921 gcttccagtg gcggcggcat gttctacttt attttgctgt tttaaaatgc tgcctgtttc 1540981 ggcgtcaact aagacttccc agtttgcagg ttcaggctcg acatagcgaa tcgtcacgtc 1541041 gtaagcaaga cgatagctgc cgtcttttgt ttctatcgct tttaattcgg ctttattgct 1541101 gtttttggcc gctccgttag aaacagcgtc tggtgatttg ccgatagctt tgaaagcgag 1541161 tgccagcgct ttttcagaag agactttttg gctgttatct gtttttgcag cagattgatt 1541221 gtgtaattca ccattgaccg catagacatt atcggattta tcgacgtgaa cgatcacttg 1541281 cgaatcttta attggcactc cgttaacgac aggcgcatat cgaaagtgct tgtatccaag 1541341 ggcatcagtc gtgctttcaa caagcttcag ccttttggaa gggtcacctt taaaaatgtt 1541401 gctgttcttt ttcaaaaact gcttgacagc cttgtcattt ggtgcagaga gttctgattg 1541461 cgcaatcgcg tttttggaga ggaaatttgt ttgattctct ttaagctgat gaccttcagc 1541521 agcctgaaca cctggcaggc tgattgataa actcataaac gaagcagcga cagcaacaga 1541581 caatttctta cctaaaccca caataaatcc ccctttttga aaatactgaa aactttatat 1541641 tgttatatta aactagcatt ctggaatact caacaaaaac taacataact agacaaaatt 1541701 gatagtattg tcctgtgttt gtttttgttg aataatatca agatgagtca agtgtcatgt 1541761 ggtggttcat tcaagagtta tgttttttac atatcaaggg gaagatgaga tatttttgtt 1541821 tcatcttgaa actttttgaa aagtccgctg tctaaccgaa tgaggcctta ataagaagta 1541881 aaggattgtt gttcgtgttg gagttattca gtcattatgt attgcatttc gaacgttatt 1541941 ttatattaag cagacaaagc accctgctga ttcaatggtc aattgttgtt ctggcgggct 1542001 tatatctttt ggtgcatcat cccaaaataa accggcagcg cacaatgttc ttggcgggtg 1542061 ttatattgcg gattgtgctg ctggcgggag tgtctgttga acttattcac caggtgcaat 1542121 caacaaactt caccagcgct tacttaagag aggacggaaa agaactgctg ccgctgctgc 1542181 attttttgtt atacggatat gtgctgctga cggcttttca ctatatgctg atgccgcgtg 1542241 atcatggcgg aaagggtaag ttttatacgt tcgaccttgc tgttgtcagt ttgccgatcg 1542301 tacaaatgat ttttagtttc ttttcgtatt ggaaggaata cccggatggg atggagccga 1542361 ttgcattcgt gtttctgttt ttcatcatca ctcttcccat tgcgttgaat gtagtgtttt 1542421 tcaagctgta ttggagaacg gataagatct tactaggctt attttatacg ctgattatcg 1542481 gactgcttgt cttgctgctt gcgccatatc ccaatcaaat ctcaaaagat tatggtgcag 1542541 taatgccata tacgatttat ttggcaatgg cgggattttt gatgagctat catctgttcc 1542601 aaaagtcagg aaaggtttat gtgcgtgtga ataagtgggt gacgatggct gtcatggtgt 1542661 tttttgtcct gctgttaaat ccgatatata acataggaac ggctgctttc gctgtatcaa 1542721 agccagcaaa tgtccatgat tcattcaatt ttgtcgggga gcacatttca tcagaaaaag 1542781 cggaacagat actaaagtca ttttttccta cggatgaaac actttatttg cacgatacaa 1542841 acatggatgt gcattatttc tactcatttg aaagcaaagg ttacaaagct gaggtagatg 1542901 aagtatcgca gctaattcgt aattatgaat acttacaaaa agcacatggg aaaaagctaa 1542961 cgaatcagga gtacaagcga aagtccatcg ctttccttga gcgacacgga cgtgtgttac 1543021 ataaggatca tatcgaaaca aaggtatctc aagaagacgg ccagacagtc gtacgtattt 1543081 acctgaaaaa tcaacttcat aaaaaagatc atgctgatga tggcgcggta ttttattggg 1543141 aaaaggaaac cttaatgggg tttagtgaag atccttcgat ttatcagctt gactctcttc 1543201 tgcatgttca tataacggaa caagacattc acgacaaagt ggaacaaatg tttacagcgc 1543261 tgaacatatc aaaacagcct tatcagatca ctgatattga aagcgacagc ctgcttggaa 1543321 gcatggtgag agttgaaaca aaagttggaa ttgttttgga atttgagggc gaatcaggtt 1543381 gtttacatag tctttcgctt ccgatgaaaa agaatatctc aatggctaac agccggctgc 1543441 agcatcagat attatcgatc ttcgatgctc gtggatcaga aaagaagaaa aaaagcagtc 1543501 agggtgacat ggtgatgtat actgattctt ctaaaacata tgagtttgtt gaagctcaag 1543561 gtcagctaaa cgtttatgta tacagcgata cacctgatca gtcattcccc tatacgtatc 1543621 gtaatggaac attggcttac gaaaaagtag cttctctata tcaggatgtc atttacaaaa 1543681 agcgtatgcg tccgattatc gttcaaagag gggatgaacg gcattatgca tggctgatca 1543741 ttattcagcc gtttggttca aatcgccatg atgcctatgt agtggatgga gaaacacaag 1543801 aggtgaaaag tctttatgaa tcataaagaa aaagagtctg tttttgtaga cttatacgac 1543861 ctgtataaag aaggagagct agaggatgaa tcaatggaat ggatgaaaca gcatgaatcc 1543921 ctatttcaaa agaatgcgga agacttaaag agtaaaactt gtttaaagag aagtcccggt 1543981 gctgaagaag aaagccaaat cagatatatg aaagtatacc tgtcttccat gtatatctgt 1544041 ttcattttat tggccatttg gatgacggtg tggttttatt tttaatgaag catagggatt 1544101 ccattgagga cttgtatcgg cagtattatc aagaaatttt aaattattta ttcagaagga 1544161 ctcatcatct tgaaacagcc aaggacttag cgcaggacac gtttgtaaaa gctcttaacg 1544221 gtctggcttc gtttaggggg cattcttcca tcagaacatg gctctacacc attgcgcatc 1544281 atacctttat caattggtac cgaagggatg tcaaatacca atttactgaa atcagcaaaa 1544341 atgaagggtt aacgcaaaca acttatgacc agcctgaaca gtatctgtca cggacggtga 1544401 aaagcgaaac actgcggcag gagctcctga agttaaaaga tcagcatcaa tccgttttga 1544461 ttttaagaga attccaagag ctttcttatg aagaaatcgc tgagatatta ggatggagtc 1544521 tttctaaggt gaataccaca ttgcaccggg ctagattaga gctaaagaaa aacatgacga 1544581 aaagtagaga ggaggagcgg atatgacctg ctttctagta agagacctgc ttcctctgta 1544641 tcttgaaggt gattgtaaaa gagaaacgga acacgttata gaagagcatt taaaaatgtg 1544701 cagcagctgc agagacatgt atgacacgat ggctgagcca tttgaattgg aaagcgaaca 1544761 ggccgttgag gaggcttatc tgccggaaga agaactgcgt tttaaacaga ggtactatgg 1544821 attactgatc atgaaagctg cctgctggtt tggagcggcg gttgccatga tgctgatcat 1544881 caaactgctg atataaaaaa agcgcttgtc cgattccggc aagcgctttt ttacattaag 1544941 cctggggatg aatcatatcg taaatagcgg caagctgttc ttgtgacagg gcactgaaga 1545001 gtttttcata aacgtcagct tgcagtggcg ttgcacctgc ttgtagcgct gcgtctttat 1545061 catagctgta cacatcatct tgtagcacaa tggctgcttg aagaatgtga atcttgagag 1545121 aaacagcgga gaaaaattgt tcaagtgcaa gtgcttcttt ttctgtgaag ccaagttcaa 1545181 ctgctttttc tgtatcaaat ttgtaatttc catcctcgag atacacacat tgtgaaacaa 1545241 tgctgaaaaa ttctgatgtc gattcccaga gtgtagcaat tacctgagcc tcttcttttg 1545301 tcattcctaa ctcgacagct ttttcgctgt caaaataata tacaccgtct tgttcgtata 1545361 tacattgatt taatatatca atgaatgtat tgagatcttc gttagtgctc gcctgatgct 1545421 ggagttgaac agcagtgtta tcaaccggtg tttttgcgct ggctgcatca ggaccgaacg 1545481 ttaatagagc agctgaggtc attgcggcag tcgttaacat agcttttttt acaaatgttt 1545541 tcttcatgtt tcttctctcc cttttatgaa ttgtgctaca aattccatta tagggagtag 1545601 tttccggtgg aggaataggc gctatggtat tttatgtgta tcgttgccga actacttttt 1545661 gaaggctgca cgtgtgatcg ttagaacgat tgtctatgta tgaaggctgt tttgcatctt 1545721 cctgactaag aaacagggga gataaggctt aaagaaatga aaaacaccgc tttctttgcg 1545781 gtgttttttg attacaatgt cgccggcggg gcaatgcttt taatcaagca agccttgttc 1545841 gcgcattttc ttttttaatg taaatccgcc gcccatgaca gcgcaaacaa gtacaatgct 1545901 ggcgataatg cctgcagggc ttttttcagc gataaagacg ccgatcagca taatgctgaa 1545961 aaccgctgca aatgcaaata atagtaaaag ccaattcatt tttttcataa attccatccc 1546021 cttttacgtc ttatattaag tttacagaaa aacgtgacgc ttttaaagag gatgtgtgat 1546081 ataatatgaa agttatctaa tttttttagg agatgaaaaa gtgaaacttc gaaatgatct 1546141 tcgcaacatc gcgattattg cccacgttga ccatgggaaa acgactctag tcgatcagct 1546201 tttacatcag gctggtacgt tccgtgccaa cgaacaggtt gctgaacgcg caatggactc 1546261 taatgatctt gaacgcgaac gcggcattac aatattggcg aaaaatactg cgattaacta 1546321 taaagataca cgtatcaata ttttggacac ccctggacat gcagactttg ggggagaagt 1546381 agaacggatt atgaaaatgg ttgacggcgt agtgcttgtc gttgacgcat atgaaggctg 1546441 tatgcctcaa actcgttttg ttctgaaaaa agctcttgag caaaacctga accctgttgt 1546501 tgttgtaaac aaaattgacc gtgactttgc tcgtccagag gaagttatcg atgaagttct 1546561 ggatctgttc attgagcttg atgccaatga agagcagctc gagttcccag tggtatatgc 1546621 ttccgcgatt aatggaacag cgagtcttga tccgaaacaa caggatgaaa acatggaagc 1546681 tttatatgaa accattatta agcatgttcc ggcacctgtt gataatgcag aggagccgct 1546741 tcaattccaa gttgcccttc ttgactacaa cgactatgta ggccgtatcg gaatcggacg 1546801 cgtattccgc ggcacaatga aagtcggaca gcaggtttct cttatgaagc ttgacggaac 1546861 ggcaaagtca ttccgtgtta caaagatttt tggtttccaa ggcttaaagc gtgtggaaat 1546921 tgaagaagca aaagcgggag acctcgttgc ggtttccggg atggaagata tcaacgttgg 1546981 tgaaacggta tgtcctgtag accatcaaga tccgcttccg gtccttcgca ttgatgagcc 1547041 gacacttcaa atgacatttg tcgtgaataa cagtccgttt gcaggccgtg aaggcaaata 1547101 tgtaacggcc cgcaaaatcg aagagcgtct tcaatcacag cttcagacgg atgtgagctt 1547161 gcgtgttgag ccaacagctt ctcctgatgc ttgggttgtt tcaggacgcg gtgagctgca 1547221 cttgtcaatt ttaattgaaa atatgcgtcg tgagggctat gagcttcaag tgtcaaaacc 1547281 tgaagttatt atcaaagaaa tcgacggcgt acgctgtgag cctgttgaac gtgtgcaaat 1547341 tgatgttcct gaagagcata ctggctctgt aatggaatca atgggtgccc gcaaaggcga 1547401 aatggttgat atgatcaaca acggaaacgg ccaagtccgt ctcatcttta cagttccttc 1547461 ccgcggattg atcggttact ctacagaatt cctatcatta acacgcggat tcggtatttt 1547521 gaaccatacg tttgacagct accagccgat gcaggcaggc caagtcggcg gacgccgtca 1547581 aggtgtactt gtgtcaatgg aaaacggaaa agcaacatca tacggtattc aaggaattga 1547641 agaccgcggt gtcatcttcg ttgagccggg tactgaagta tacgaaggaa tgatcgttgg 1547701 agagcataac cgtgacaacg accttgttgt taacgtcagc aaaatgaaac agcaaacaaa 1547761 cgtccgttct gcgacaaagg atcagacaac tacaattaaa aaagcgcgca tcatgtctct 1547821 tgaggagtct ctagagtact taaacgaaga tgaatattgt gaagtaacac ctgaatccat 1547881 ccgtttaaga aagaagatcc tcaataagaa cgaacgtgaa aaagcagcta aaaagaaaaa 1547941 aacagcagga ttgtcttaat ctcgtgcaga atttgaaaag atagaacccg tacgtttaca 1548001 ggggagggaa tctttttgaa tgacgtaagc gaacgcctgt cgttcttcgc cgctctatat 1548061 caagtagacc ggcagcctgc ggcaggcatg tggctgctgt acggcacgat ttttgtgttg 1548121 gccgttattg tatttaagct tggatttgct aaacggcttc ctgtattaaa atctgcagtg 1548181 gtgtatgtat ttttggcttt gggctgcact gttttgactt ttttaggggt gtttttgccc 1548241 gtggcagaag gattggtcgt cgctgcgctg attttaatca tttacaaaat ccggctgtat 1548301 cagtcgaaaa aaggacagtc tgcaaaatca taaaagactc agctgaaagc tgagtctttt 1548361 ttgtgttctg tatggttaag cggccgcttt attttttgac tttttctttt ttctgctgtc 1548421 ccgggtgaaa agtaaatttt cccgttttca gccgttcctc tgtttttttg gcaatccgat 1548481 cgtggcattc ctggcacata tatgtatgga tcgggcggtt tcgaagccgt ttcgcgatca 1548541 gggtatcatc atcaattgtt tcaattttat cgcaaataga acatttgacc ctcatcatat 1548601 cacctctttc actaacatgt attataccac ggatcagaag ctgtccaaaa taagaaaaag 1548661 ctaaagcgca aggctatagc ttagtcattg ttgttctttt tcatatgatg atcagattga 1548721 tcgttttgtt ccttctccat ttcctgttgc tgttttctat ttaattggtc attttgctgc 1548781 tttgtttgcg gttcatcttc attgtcaatc acatcgttag gcacttcggg aagcactcgg 1548841 ccgacaattg cagctaattc atccagtata cctgttaccg gatggccctc gctgatttct 1548901 ctgctcattt cgcgaaggcg gctgaccgta tcgggatcag caatgactac tgcgttggcg 1548961 ccatatcgat cattctttag cgcctgagct acagaatatt taatggtttc cactttgctt 1549021 ctgtccaaag tatcatcgac atcaatccca acaacagcat agcctcccag cacaacggct 1549081 gttgcatcct tgacgtcggg gtttttttca gcaacgctga caagatgctt ggcaatatcc 1549141 gttcttgttc cattgtcttt tgtttcttga gttgtgtcct ttacgtgaat cggtttagtc 1549201 tcctgctgtc ttgttgattc tttttcaaca ttctggccct gttttccttg ttgataggca 1549261 caagcggaca ggataagtgt cagctgtatg ataatgaaaa gaattcgcac ttgcgggttc 1549321 cctccttaaa atgctttcat taattttatt gttgaattaa ccttctatct ttatgcacaa 1549381 aaacatatat tttagcaggc attcaccttt ttcatcaaaa gagaagcagg aagaactttg 1549441 acccttatat caggaggctg agacttgagt aaaatttatg tgttagatac gaatgtgtta 1549501 ttacaggatc ctaacgcgat attttctttt gaagaaaatg aggttgtcat ccctgctgtc 1549561 gttttagaag aggttgattc aaaaaaacgg tatatggacg aagttgggag gaatgcaagg 1549621 cacgtatcta agctaatcga tgcgctaaga caaaagggca ggctgcatga gcatgtaccg 1549681 cttgacaccg gcggcacact gagaattgaa ctgaatcatc gttcgtttca ccagctgcaa 1549741 gagatcttta ttgaaaagac gaacgataat cgcatattag ccgttgcgaa aaacttaagc 1549801 ctcgaggaag aaaccaagga aaatggcagg ccggttatcc ttgtcagtaa ggatgtactg 1549861 gtcagggtta aagccgacgc aatcggactg cttgctgaag atttcttgaa tgaccgggtt 1549921 gtggacaatg atgaaatgta cagcggctat aaagatttat atatcagcca gcagctgttc 1549981 agctcttttt acgggaaaaa tcaaatttca gtaaacgatg tgaaacagca tgcgttttat 1550041 ccgaatcagt ttgctttaat gaaggatgag ctaggagggt cctcctcggc agtcggaatt 1550101 gcagacaaaa ccggaacggt attaaaaaga ctcgtatttg atgatgaaca tatatgggga 1550161 atcaggccga aaaatgtaca gcagacaatg gcattagagc ttttgctgcg ggaagatatt 1550221 ccgcttgtca ccctgatcgg caaagcggga accggcaaaa cgctcttagc tttggcggca 1550281 gggctattac agacagaaga cttgggaata tataaaaagc tggtcgtcgc aaggccgatt 1550341 gttcctgttg gcaaggacat cgggtatttg ccaggcgaaa aagaggaaaa gctaaagcct 1550401 tggatgcagc cgatttttga caacttagag tttctgttta atgcgaaaaa accaggggag 1550461 cttgatgcta ttttggcggg aattggctca attcaggtag aggcgctgac ttatatcaga 1550521 gggagaagca ttccagatca atttattatc attgatgaag cgcaaaattt gaccaggcat 1550581 gaggtgaaaa cgttgctgac gagagtcggt gagggcagta aaattgtctt aatgggcgac 1550641 cctgaacaaa ttgatcaccc atatttagac agtctgaaca atggtttggc ctatgtggtt 1550701 gagcggttta aaggacaacc catctcaggc agcgtgaagc tgttaaaagg tgagagatca 1550761 ggtctcgccc agcttgcagc tgatttgctg taacacttaa atgatttcga tctcttttac 1550821 atcggtaatc ggctgtttgt gatgaaccgg gtcttcaaag taaatatgca cggggccgcc 1550881 ttcttgaatc ggcttgcctg cctcactgaa atggacaata ctgttcagag cggtttccag 1550941 agaaacggcg gcctttcccg aacttgtgac aaatacacat tgtgtcgcag agctgttcgg 1551001 ctcagcattt ttcaggacag tcccaagtct cattgcgaaa ctgccgttca tcagtttttg 1551061 cttctcatat tgcttttccg tctttaatgt aggcggcgcg attcgcccct ctctgatgac 1551121 gcgttccgga tcaaggtcgg attcatcccc ggctgattgt aaatatgtgt cttgactgtc 1551181 ccctttgcgg tcaaacgaaa atttgcgatc atcaaaaatc catacgcttg gatcaatggt 1551241 aattggatat gtaacattgc cttttacttg gataacgctc atgatatgac ccccttctct 1551301 caaaattata aaagttttcg catgaattgt cactttgtgt acaaattatg tgtattgaaa 1551361 tgctgaggga acgagggtgt ttgcatggta tgccagcata atgatgagct tgaagcctta 1551421 gtgaaaaagg cgaaaaaagt aacggacaag ggggaggtag ccagctatat tcccgccttg 1551481 gcaaaagctg ataaacacga cctgtcagtg gcgatttatt attccaataa tgtttgtctg 1551541 tcagcaggtg acgtagaaaa aacatttacg cttcaaagta tatcgaaagt cctttccctt 1551601 gctttggtgt taatggaata cggcaaagat aaggtcttca gttatgttgg acaggagccg 1551661 accggtgatc cgtttaattc aattatcaag ctcgaaacag tgaatccgag caagccgtta 1551721 aaccctatga ttaatgccgg ggcattggta gtgacaagtc tgataagggg aagaacggta 1551781 aaagagagac ttgattattt gctttctttt atcagaaggc tgacaaacaa ccaagagatt 1551841 acatactgcc gggaagtggc tgaatctgaa tacagcactt caatgattaa tcgggcgatg 1551901 tgttattata tgaagcagta cggcattttt gaagatgatg tagaggcagt aatggattta 1551961 tatacgaagc aatgcgcgat tgagatgaac agcttggatt tagcgaaaat cggatctgta 1552021 ttcgcattga acggcagaca tccagagact ggggagcagg tcatctcaaa agatgtcgct 1552081 agaatttgca aaacgtttat ggtgacgtgc ggaatgtaca atgcaagcgg ggaattcgca 1552141 attaaggtcg gaattcctgc gaaaagcggc gtatccggcg ggataatggg catttcgcct 1552201 tacgatttcg ggatcggcat attcggcccc gcattagacg aaaaagggaa cagcattgca 1552261 ggtgtaaagc ttttggaaat aatgtctgag atgtacaggc tgagtatttt ttaatttatg 1552321 tcatatgctt aaatcctctt gcattttctg ttgataccct ttatgataaa tagaagaatt 1552381 aggtactcgc ctggggaacg gagggatact tttggcttca gagatgatag ttgaccatcg 1552441 gcaaaaagct tttgaactct taaaagtgga cgctgagaag attttgaagc tgatccgagt 1552501 acaaatggat aacttaacga tgcctcaatg tcctctatat gaagaggttt tagatactca 1552561 aatgttcggg ctttcgaggg aaatcgattt tgctgtccgc ctgggattgg ttgatgaaaa 1552621 agacggtaaa gaccttttat acacattgga gcgcgaattg tctgctttgc atgacgcgtt 1552681 tacagctaaa taaatgataa aactcaaact tattaacagt ttgggttttt ttataaccgc 1552741 tatttttctc tcatctcata aaagacggtc tttttttaca cattccttcc gaatcgtata 1552801 gagattcttc gtctcgtttg ataaattgta gtaaaataaa aaagataaat acataaaaac 1552861 catagataat ggaagttaga agcagggaag aggatgttat gttaaaaaaa atgctaaaat 1552921 cttatgatta ctcactgata ttcgcaatcg ttttattatg cggattcggt ttagtgatgg 1552981 tatacagctc aagcatgatt acggctgtct cccggtatgg agtaagcagt aattttttct 1553041 tcatgcggca gctgtttgct ttaattgcgg gtggcgctct atttattctc atggcgttgt 1553101 ttccttataa agcactggcc catcaaaagt ttcagaaggg gatactgctt gtatctgttc 1553161 ttgcgcttat ctcactgttt gttttcgggc atgttgccgg aaacgcgcag agctggttta 1553221 aaatcggcgg aatgagtatt cagccggggg agtttgtgaa actggtcgtg attttatacc 1553281 ttgcagccgt atatgcaaaa aaacaaagtt atatcgacca tctgttaacg ggagtagccc 1553341 ctccggtagt catgacgctt ataatttgtg ggttaattgc catgcagcca gatttcggta 1553401 cagccatgat tatagggtta attgcgacgt gcatgatctt gtgctccggc ttcagcggaa 1553461 agacgctggt gaggcttgtg atactgggcg gaattgtttt cattttagtc agccctatta 1553521 tctatttgaa tcaggacaaa attttaactg aaggccgttt agcgcgtttt gagagtcttg 1553581 aagacccatt taagtatgca aattcatcag gtttgcaagt gatcaattct tattatgcga 1553641 tcagctcagg cggcattttc ggcctggggc tcggtgaaag tatccaaaaa tacggatatc 1553701 tgcctgaatc acacactgac tttattatgg ctgtcattgc tgaagagctc ggcatttttg 1553761 gggtattgtt tgtgattttc ttattgggtt ttgtcgtcat aaaaggtttt tatattgcca 1553821 gaaaatgcga ggacccgttt ggaagtcttc tggcgatcgg catttcaagc atgattgcca 1553881 tccagtcgtt tattaacctt ggcggtgtca gcggattaat tccgattaca ggggttacgc 1553941 tgccatttat cagttacggg ggctcttctt tggtgctgct gctggggagt atggggatat 1554001 tagcgaatat cagcatgttt gtgaaatatt cagagaataa gaaaaagaaa gagcccttgg 1554061 cgccgaaggg aatgaaaaag aaacagctca aaaaaactgt ttatctgtaa aaaacaagtg 1554121 tgtacagggg aaggatattc cgctatgata gattatattc cattcgggta agggggagaa 1554181 aagtttgtct cagcaatcga tacaaaaagt attagtagca aacaggggag aaattgcaat 1554241 ccgaatattc cgggcgtgta ccgagttgaa tattcgtaca gttgcggtct attcaaaaga 1554301 agattccggt tcctaccatc ggtacaaagc ggatgaagca tacttggtcg gtgaagggaa 1554361 aaaaccgatt gatgcttacc tggatattga aggtatcatt gatattgcga aaagaaacaa 1554421 agtcgatgca attcatccgg gatacggttt cttatctgaa aatattcatt ttgcgagacg 1554481 atgtgaagaa gaaggcatcg tattcatagg gccaaaatcc gagcatctcg atatgtttgg 1554541 tgacaaggta aaagcgcgtg agcaggcaga aaaagcggga atccccgtga ttccgggaag 1554601 cgacggtcct gccgaaacgc ttgaagccgt cgaacaattt ggacaagcta acggttatcc 1554661 gatcatcatt aaagcctcgc ttggcggcgg cggccgcggt atgcggattg tcagatctga 1554721 aagtgaagtt aaagaagcat atgagcgtgc taaatcagag gcgaaagcag cctttggcaa 1554781 tgatgaagtt tatgtagaaa aattaattga gaatccgaaa catattgagg ttcaggtcat 1554841 tggagacaag cagggcaatg tcgtccatct ttttgagagg gattgctccg ttcaaagacg 1554901 ccatcaaaaa gtcattgaag tggcgccgag tgtctcgctg tcacctgaat taagggacca 1554961 aatttgtgag gctgcagttg cgcttgccaa aaatgtaaac tatataaatg cggggacggt 1555021 cgaattcctt gttgcaaaca acgagttcta ctttattgaa gtaaatcctc gcgtacaagt 1555081 tgaacacacg ataacagaaa tgattactgg tgtcgatatt gttcaaactc agatccttgt 1555141 tgcccaaggg cacagccttc acagcaaaaa agtaaatatt cctgagcaaa aggacatttt 1555201 tacaatcggc tatgccattc agtcacgggt tacgactgag gatccgcaaa atgatttcat 1555261 gcctgataca ggaaaaatca tggcttaccg ctcaggcggc ggttttggtg tccgtcttga 1555321 taccggaaac agcttccagg gcgccgtgat cacaccatac tatgattcac ttctcgttaa 1555381 gctttcaact tgggctttaa cgtttgaaca ggcagctgcc aaaatggtgc gaaaccttca 1555441 ggagtttaga atcagaggca taaaaacgaa cattccgttc cttgagaacg ttgcaaagca 1555501 tgagaagttc ctgacagggc aatatgatac atctttcatt gatacaacgc ctgaattatt 1555561 taatttccct aaacaaaaag accgcggaac gaaaatgctc acttacatcg gcaatgtgac 1555621 agtgaacggc ttccctggaa tcgggaaaaa agaaaaaccg gcgtttgaca aaccgttagg 1555681 cgtaaaggta gacgttgatc agcagcctgc cagaggaaca aagcaaattc tcgatgaaaa 1555741 aggtgcagaa gggcttgcaa attgggttaa ggagcagaaa tctgtccttt taactgatac 1555801 gacattcagg gatgcccacc aatcgttatt ggcaactaga atcagatcgc atgatttgaa 1555861 aaaaatcgca aatccgacgg ctgcgttatg gcctgaacta ttcagtatgg aaatgtgggg 1555921 aggcgcgacc ttcgatgtag cctaccgatt cctgaaagaa gatccgtgga aacgtttgga 1555981 agatcttcgc aaagaagtgc cgaatacctt attccagatg ttgcttcgct catcaaatgc 1556041 ggtcggctat acgaattatc cggacaatgt gattaaagaa tttgtgaagc aatcagctca 1556101 atccggtatt gatgtgtttc gtattttcga cagcttaaac tgggtaaaag ggatgacgtt 1556161 agccattgat gctgttaggg ataccggcaa agtggcagaa gctgcgattt gttatacggg 1556221 agatatcctt gacaagaacc ggacgaagta cgaccttgca tattatacat cgatggcgaa 1556281 ggagcttgag gcggccggag cccatattct cgggattaaa gatatggcag ggctgttaaa 1556341 accgcaggct gcatatgagc tcgtttctgc gttgaaagaa acgatcgaca ttccggttca 1556401 ccttcatacg catgatacga gcggaaacgg tatttatatg tatgcgaaag ctgttgaagc 1556461 cggcgttgat atcatagacg tggcggtcag ctcaatggcg ggattaacgt cacagcctag 1556521 cgcgagcgga ttttatcatg cgatggaagg caacgaccgc cgtccggaaa tgaatgtcca 1556581 aggcgttgaa ttgctgtccc aatattggga gtcggtgcgt aaatattata gtgaatttga 1556641 aagcggaatg aagtctccgc atactgaaat ttatgaacac gaaatgccag ggggccaata 1556701 cagcaacctg cagcagcaag ccaagggagt aggccttggc gaccgctgga acgaagtcaa 1556761 ggaaatgtac agacgcgtga acgatatgtt cggtgacatc gtcaaggtaa cgccttcctc 1556821 aaaagtagtc ggagatatgg cactctacat ggtgcaaaac aatctgactg aaaaagacgt 1556881 ttacgaaaaa ggtgaatctt tagatttccc tgattctgtc gtggagcttt ttaaaggaaa 1556941 tatcggccag cctcatggcg gattcccaga aaaactgcaa aagctgatct taaaagggca 1557001 ggagccgatt acagtcagac cgggcgaact gcttgagccg gtgtcatttg aagcgatcaa 1557061 acaggaattt aaagagcagc ataacttgga aatttcagat caggatgctg tggcatatgc 1557121 cctttatcct aaagtcttca ctgattatgt gaaaacgaca gaaagctatg gagacatctc 1557181 ggtattagat acaccgacat tcttctacgg tatgacatta ggtgaagaga tagaagttga 1557241 aattgagcgc ggcaaaacgc tgatcgttaa gctgatttca atcggtgagc ctcagcctga 1557301 tgccacccgc gtcgtttatt tcgaactcaa cgggcagccg cgtgaagtag tcattaaaga 1557361 tgaaagcatt aagtcttccg ttcaggaaag gctgaaagca gaccggacaa atccaagcca 1557421 catcgcagct tccatgcctg gaacagttat taaggtattg gctgaagcag gcacaaaagt 1557481 caataaaggt gatcatttga tgattaatga agcgatgaaa atggaaacaa cggttcaggc 1557541 gcctttctca ggaacaatca agcaggttca tgtgaaaaat ggtgagccga tccaaacggg 1557601 agatctgctc cttgaaattg aaaaagcata aaaaacaaag agtgtatatc aatgatatac 1557661 actcttgttt tttatataga aaatgtggag tgaaacagat ggttagaaga gatataaggg 1557721 gacttcagag attatagagt actgtcacaa gcccaaaata aaaagaggct tatacagcca 1557781 atattttaga tgctttgtag tatgccgtgc atatttcttt aagcactatc tgatttaaaa 1557841 ggctttaata cttatgttcg cgagctatag atccatatga aatttctata atcacgatga 1557901 gaaaggggac agaccgaagt gagccgctca ctgatcatca agttcggcga aggctggcga 1557961 ttgaaacgca taaagcgcca aaaaacaaga cataaaaaag accaaagccg cctaaggctt 1558021 tggtcttgag tccttatgat tgcctggatt cataacggaa acgagcaatc aataataaga 1558081 agtagcatag aacgccaaac agacaggcaa taaagaacga gtgggcaagt gcaaagccca 1558141 gagccagttc agagtatacg atcataatac cggacagtgc ctgtaatgta atgaaaataa 1558201 gacatgagat ccatccccaa aagatctgtt tttgatcttt ataggaagta atagcatgaa 1558261 cagcggcaac aataatccat acaaataaaa gtaaggctgc tgctctgtgg cccatttgca 1558321 cccattcatg gaattgggtc ggaagtccat tgttcagcgg gctgcacagc ggcacattag 1558381 gacatgccag acttgattca gtgtgtctta catatgcgcc tgtatacaca acgatatagg 1558441 aatatattaa aattcctatc atgtgaaatt gcatcttttt gccgatttga agcggcttaa 1558501 ccagtgttct gactgattta tcagcttcaa atatgagcaa tgttaaaata agcactgaag 1558561 caaaagaaat taatgagatg ccgaagtgaa gcgccataat cagcgcgttc gaaccgaata 1558621 cgacagccaa tgcgccaagc aatgcctgaa gaaataaaaa gataattgac atgatcgcga 1558681 gaaacgttgt ttcacgaaaa atcggcgtga tttttctcca tgaccaaaac gcaaggctta 1558741 gcacaaggat aatagagatt ccgcttgcga atcggtggct ccattcaata attgaagccg 1558801 gattcagttc agggaaaaaa cggccgtgac acagcggcca ctgtctgccg catccttggc 1558861 cggaacctgt ttttgtaacg agggcacccc cgattaaaac aattagcatg acaaatgtcg 1558921 tcagaacacc gagagctttt aatgctttat tcatacaata ttcaccttct taacatactg 1558981 ctgcaatttt atatacgttc caagtgtaag cgaatatgtg ttttgtggca attcccagag 1559041 ccttttgttc acaaaaatat aatagaatga cggcttctgg aaaatgtaca cttgattatt 1559101 catgccgggt ctgatagaaa taaggtaaac gcaatgccga tttggagatt gccttcatct 1559161 ttggtaaaat tcataaaaag ttcacaaata aattcctgtt tgtcgtttaa tatttaatag 1559221 gatgtttttt tacaagatgt tatcttgtat gatagagttg caggttattt tattctcctg 1559281 cgttaggttt gtaagggagg tttacgttat ggctaactcc agaatcttaa atgatacagc 1559341 tatagacgga caaattgaag aaacaacggc atggaaagat tttctgtccc ttattaaaat 1559401 agggatcgtc aattctaacc tcatcacgac tttcactgga atgtggcttg cactgcatat 1559461 atccggttta agttttttag gcaatataaa caccgttctt cttacgttaa tcgggtcttc 1559521 actgattatt gcgggctcct gcgcgatcaa taactggtat gaccgggaca ttgaccatct 1559581 tatggagcgt acgaaagtaa gaccgacggt tacgggtaaa attcagccga gtcaggcgtt 1559641 atggtctgga attttgctgg ttgctttagg attgatcatg ctgctgatga caactgtcat 1559701 ggctgctgtt atcggtttta tcggagtctt tacgtatgtt gtattgtaca caatgtggac 1559761 gaaacgccgc tatacgatta acacagtagt aggaagcgtt tccggtgcag tgccgccgct 1559821 tattggatgg acggcagtgg aagggaatat cggtgtcgta gcatgggtgt tattcatgat 1559881 tttatttatt tggcagattc ctcacttctt agcattggct attaagaaaa ctgaggatta 1559941 cagagctgca aatattccga tgcttcctgt cgtatacgga tttgaagtga caaaaagaca 1560001 aattattgtg tgggttgcgt gcctgatgcc gcttccgttt ttccttggta gcctgggtct 1560061 tccgattgtc attctcggct tgctgttaaa tatcggctgg ctgattcttg gcttaatggg 1560121 attccgctcc aagaatatca tgaagtgggc aacgcagatg ttcgtttact cgcttaacta 1560181 catgacaatc tatttcgttg ccatggttgt cttgacgctt ttctaaaaaa tagatatgat 1560241 gcttgtttta tcgcttcaaa ataaacgatg acaactagta aatgccgcct tgacctcttg 1560301 tttaatcagg cggctttact tttatacata gatggcattt tgagtaaaaa aactcataat 1560361 ttaagagaag aggaaatgta agtgctttat tggtgatagg ttggatggcg atagatttcg 1560421 atccgctttc cgcctttgta ttgaccagaa aaggggttgg gtgaaatggt aaagcattgg 1560481 cgtcttattt tattattagc cttagtgccg cttctattaa gcggatgtgg aaaacctttt 1560541 ttatccacgc tcaagcctgc tggcgaggtg gctgataaac agtatgacct gacagtgctc 1560601 agcacattga ttatggtggt tgttgttgca gtagtatctg ttatcttctt ttatgtgatt 1560661 gtgagattca gaagatcacg ggtcggtgag aacacgatac cgaaacaggt agaggggaat 1560721 aaatttttag aaatcacatg gaccgtgatc ccgattttgc tgctcattat tcttgtgatt 1560781 cctgttgtat tatatacgct ggagctagcg gacacatcac caatggataa aaaaggccgc 1560841 aaagctgagg atgctcttgt agtcaatgtt agggcaaatt tatactggtg ggagtttgag 1560901 taccctgatt acggcattat cacaagccag gagctgattg taccgacaga tcagcgtgta 1560961 tattttaatt taaaagcctc tgatgtaaaa cattccttct ggattccttc agttggagga 1561021 aaacttgata cgaatacgga taatgaaaat aagttcttcc tgacatttga ttcaaaacga 1561081 agcaaagagg caggagatat gttttttggg aagtgtgcag agctttgcgg cccttcacat 1561141 gcgctgatgg attttaaggt gaagacgatg tctgcaaaag aatttcaggg ctggacaaaa 1561201 gaaatgaaga actataagtc tacagcagag agcgatttgg ctaagcaggg tgaagaactg 1561261 tttaaagaga aaaactgcct gagctgccat gcggtagagc cgaatgataa gcgtgcagaa 1561321 gccgctagaa cggcacctaa cttggcgacc ttcggtgaaa ggacaaaagt ggcaggggtg 1561381 aaagaggcca acaaagaaaa tgtgaaggct tggctgaagg accctgacag cataaagccg 1561441 gggaacaaaa tgacaggcac atatccaaag ctctcagaca gcgaaacaaa tgcgctttat 1561501 gaatacttaa aaggcttaaa agcggaaagc aagtagggaa gaaagggaga tattggggga 1561561 ggtcacatat gttgaatgcg cttacagaaa agcggacgcg cggatctatg ctttgggatt 1561621 atttgacgac ggtggaccat aaaaaaatcg caattcttta tttagtggca gggggattct 1561681 tctttcttgt cgggggaatt gaagcgatgt ttatcagaat tcagcttgca aagccggaaa 1561741 atgcgtttct cagtgctcaa gcgtacaatg aagtaatgac tatgcacgga acgacgatga 1561801 tctttctggc tgcgatgccg ctcttatttg ccttgatgaa tgcggttgtg cctttgcaga 1561861 tcggggctcg ggacgtttcg tttccatttt taaacgcgct tggtttttgg ctcttctttt 1561921 tcgggggcat tttcttaaat ctaagctggt ttttgggcgg agcgccagat gcgggctgga 1561981 catcatatgc ctcactttcg cttcattcta aagggcacgg catagacttt ttcgtcctcg 1562041 gactccaaat atcggggctc gggacgctga tagccgggat taactttttg gccacgatta 1562101 tcaacatgag ggctccgggc atgacgtata tgaggctgcc tttgtttaca tggacgacat 1562161 ttgtggcctc ggcattgatt ttgttcgcgt ttccgccgct tacggttgga ttggctctca 1562221 tgatgctgga tcggctgttc ggaaccaatt tctttaatcc ggagcttggc ggaaatacgg 1562281 tcatttggga acatttattt tggatcttcg gccacccgga ggtttatatc ctaattttgc 1562341 ctgcattcgg tattttttct gaggtcatcc ctgtgttcgc cagaaagcgt ttgtttggct 1562401 attcttcaat ggtttttgca atcgtgctca ttggctttct gggctttatg gtttgggtgc 1562461 accacatgtt cacgactggt ctcggcccga ttgcaaatgc gatttttgcg gttgcaacaa 1562521 tggctatcgc gattccgacc gggattaaga tttttaactg gctgttgacg atttggggag 1562581 gaaatgtgaa gtatacaacc gctatgctgt atgctgtctc atttattcca tcctttgtgc 1562641 tcggcggtgt gacgggagtc atgctggcag ctgctgcggc tgattatcag tttcatgata 1562701 cgtattttgt ggttgcgcac ttccactacg tcattattgg cggcgttgta ttcggccttt 1562761 tagccggtgt tcatttctgg tggccgaaaa tgttcggtaa aattctgcat gaaacgatgg 1562821 ggaaaatttc atttgtattg ttttttatcg gctttcacct cacgtttttc attcagcatt 1562881 ttgtcggctt aatggggatg ccgcgccggg tttatacgtt tttgccagga cagggtctgg 1562941 aaaccggcaa cttgatcagt acaatcgggg cgttttttat ggcggcagct gttattcttc 1563001 tgctggtcaa tgtcatatgg acatcggtaa aaggtgaata tgtaggtgct gatccatggc 1563061 atgacggacg tacgctggaa tggaccgttt cttcaccgcc gccggagtat aactttaaac 1563121 agcttccttt tgtcagagga cttgatccgc tttggatcga gaagcaggca gggcacaaat 1563181 caatgacgcc ggcggaaccg gttgatgata ttcatatgcc aaacggctca atcctgccgc 1563241 tcatcatttc cttcggcctt tttgtcgcag cgttcgggct gctgtacaga agtgattacg 1563301 cttggggcct gccggtgatc tttatcgggc tcggcatcac atttattacg atgctgcttc 1563361 gttcagtaat tgatgatcac ggctatcata ttcataaaga ggaactgccg aacgatgata 1563421 aaggggtgaa ggcataatgc aagttcaaga aaaattcacc gcagaaacct ttccagcttc 1563481 tcctgaaaaa gtaaccctgg aagggaaaaa taaattttta ggcttttggc tttttcttgg 1563541 cggagagact gttctgtttg cgtctctctt cgccacgttt cttgcgcttc ggaattcaaa 1563601 tgccggtgat ccgcctacga cggaaatgtt cgatgtgaca cttgtattca ttgccacaat 1563661 gcttctatta acgagcagtt taacgagtgt gtacgcgatg taccacatga agaacttttc 1563721 cttcggcaag atgcagcttt ggctgggaat tacgatttta ttgggggcgg gctttttagg 1563781 actggaaatc tatgagttca agcattacac ccatgaattt ggctttacca tcacaagctc 1563841 tgcccttggt tctgcgtttt acacgcttgt cggtacacac ggcgcccacg tggcatttgg 1563901 gcttatgtgg atcagcacgc ttatgatccg caatgccaag agagggctga atctgtatac 1563961 ggcgcctaag ttttacgttg ccagccttta ttggcacttt attgatgtcg tgtgggtctt 1564021 catctttacc gttgtatatt taatggggat ggtgggataa acatggtcga taaaaaaagc 1564081 agagggcata tcaatagcga ccttgaattt aagaaaaaaa agcatgcccg ggagatgaaa 1564141 tatcaagtcc tgtcttttgg tttaatgatc ggtcttacga ttgttgcatt tctgactgtg 1564201 gccacggacg gtgtcggcag ctggtttacg attcctttca ttattttgct agctgcaatt 1564261 caagtcattt ttcagctgta ttatttcatg catatgaatc agaaagggca tgaggcgccg 1564321 gcactgtttt tgtattcagg ggtgtttgtc gcgtttatca ctgtgcttgc gtttgtgaca 1564381 attatatggt ggtaatttga acagccgccg gaggtgaaga aatgaatcag ttggagatat 1564441 ttgggtttcg cgcgatgtgg agcccttatc ttttttgtat cctgttaggc attacggcgc 1564501 tttatctcta tttttacagg cgaatgtctt caaagccgaa tcgaataact ggtaaagaga 1564561 tggtgtgctt tctgtcggcg atgctgtttt tatatgcagc cgagggaagc ccggttgatc 1564621 tgctcggaca tattatgttc agtgcgcata tggtgcagat ggccgtcctg tatttggttg 1564681 tcccgccgct gttaatcgcg gggattcctg catggctctg ggaaaaaatc attttcaggc 1564741 cttcaatcaa accggttttt tcctttttta cgacgccttt aattgctttg cttttgttta 1564801 acggcatttt ttctttatat catgtaccgc ttatatttga tactgtcaaa acagatccgt 1564861 tttaccatac attaatcact tggcttatct ttgtgcttgc gttcttcatg tggtggccgc 1564921 ttgttcataa ggttgagcgt ctacggcagc tcagcggctt gatgaagctg ggttatatta 1564981 tggcggacgg tatgctgctc acacctgctt gcgccttgat catgttcagc ggtgcaccgt 1565041 tatacgccac ctatacagat ccggctttat gggctgaggc aatgaggctt tgcgtgccag 1565101 cggatatgat ggggcaggtc ccattaacag ggccagagat gttgaataca ctgcctttgt 1565161 tagaggatca gcagctcgga gcagtcatga tgaaaatcat tcaggaaatt gtgtacggta 1565221 cttttttggc cgttattttt ttccaatggg tgaagaaaga aagggaaaag gacgggcagg 1565281 aggagccgcc gtatattcag cagacgatat cataaaaggt acagcgaaat atgctgtacc 1565341 ttttcgttac atttgaactg tttttaacat gttggctatg tcctgaatca gtgccttgct 1565401 ttttgtcaca acctgtacgg gaaactcttc cgtttctcca tattctactc catgagggta 1565461 gtaatgcttt cctaggagag gggacattaa ttgaatcacg gcgcgcccgc ttccgacatc 1565521 gccttctgcc gcaatacctt gtatccgcag gtaaaacgta ccctcaatcg tcgaaaactt 1565581 cttgtcatag gtgactctct cgtaatccca ttgacccgct ctgataagac ctttgctttc 1565641 cattaagtcg tctagccagc tgagctcagc cttaacccct tcaagtccgc tttcagtaaa 1565701 cttcaacact gacccctcct tataaaaatt acctttcctg acaatcatag tatgaaagcg 1565761 ttaaactttc aatgaatctt cttcttttga aagtatgcaa aaattaaatt ttgacgacaa 1565821 tagcactaga ctaaaggagg ttaaacggat gacaaaaata aaagatctga tgacagccga 1565881 cttgcaatat tgcacggtat tagataatgt atatgaagct gcagtaaaga tgaaggacgc 1565941 aaatgtagga gcgataccgg tagttgatga ggacggggaa acattggtcg gcatcgtaac 1566001 cgaccgcgat ctcgtattaa gaggaatcgc catcaaaaaa ccgaactcgc aaaaaatcac 1566061 tgacgcgatg actgaaaaac ctgtcagtgt ggaggaagat gcttcagtcg atgaggttct 1566121 tcatttgatg gcatcgcatc agctcagaag gataccagtt acaaaaaata aaaaactgac 1566181 tggaattgtc acgcttggtg atctttcttt atctgagcaa acgaatgaac gtgccggcag 1566241 cgccttatcg gatatttccg aaggggataa tagagaagaa ggcttttttc attaacacat 1566301 aaatctttga catgttaaat aggctgtatt gtaatgggat gtaaacaaga gattgtgaat 1566361 cgccacgggg gtgatagatt gaaaaatata ttgagagcaa tggttatcct tttgattatc 1566421 tgcggaacct atgttctgtt tattcaatat ggatctgttc ctgaaaagaa atcaaatgac 1566481 agcgagcctc aggtgtcgaa tgaggaagcg caaagcggca aacgaataca tatgccgact 1566541 tcagggttat tgtccttcat gggcaagcac gccgatgaag taacgaaaaa gcttggggaa 1566601 cctgaacgta ttgacccttc ggcttatgat tacgattggt gggtatacaa tcaaggtaag 1566661 gatcaatata tccaaatcgg ggtattaaac aataaagtgg tcacattatt cgcgtcgggt 1566721 aatgatatta acgccaagcc tttcaaaatt ggagaatcaa ctggcgaagt attcaagacc 1566781 acccaggtgg caccatttgt gaatgtagag tataaaggaa attcctatcg gtttgaattt 1566841 tctgaagaag atatcaatac aagaccgact gtaaaggtag gaaagatgta tgtccagctg 1566901 tatatggaca aatttgaggg gaagctatcc agcatcaggg cgtttgatgc gcagaccttt 1566961 gtaaagcaaa gaccttatga ggtagtgtac cgcggggaat taattaaacc gaaagccgtt 1567021 tcagatgaga aatggaaaaa gatccaaaca acgagcgaaa agcaaatcct tgatttgacg 1567081 aatgtcatac gcgttaaaca tggacttgcg aagcttgagt gggatcagcc aacggcggaa 1567141 gtggcatttg ggcatagtga ggatatgaag gaaaataatt atttctccca tgtctctaaa 1567201 aaatacggct cgctgaaaga ccgcttagaa gaagggcatg ttgattttca gcaagcggga 1567261 gaaaatatcg catacaatta tgtggacggt ccggctgctg tagaaggctg gctgaatagc 1567321 gaaggccatc gaaaagcgct tctgaattca gattatacgc atcttggtgt cggagtagac 1567381 cggaaatatt acacccaaaa ctttattaag cgatggtaat gaaagccgcg gacgaatggt 1567441 tcccggcttt ttctatttcc atacaagctg gtctgaatga atgtgctgat agcttacaga 1567501 taaggccgtt tcccatccct tcagtcaggc tttttcacca gtgtataggg atatcgctaa 1567561 aaattcattt gggaatgaat ataggcgaac acaatgcccg acaaaacgat acattgtagt 1567621 aggtaacgat tttcggaggg ggtgaggatt gtggcgaatc aacatgccaa tcattcaatc 1567681 aatgacttta aacaattcgt caaaaagcat cccaagctga taaaagaagt gcgcaaagaa 1567741 caaagaagct ggcaggacgt atatgaaaat tgggtcctct tcggggagag cgacccgatt 1567801 tgggatccat atcgggaacc ggaagaagct tctgaagctg tgcctgaaac accgcaaaaa 1567861 aatgattttg tctcgaaaat ggtgacagcg gtgaaaaaga tggatgtcaa tcaaatgaac 1567921 gaacaaatca ataaaatgag ccagtcgatc tcatcgttgc aaagccttct taatacattt 1567981 tccggaagcg gacagaagca ttctcagcca ggctctggac agcatccttt ttcttttcga 1568041 aaggattaaa aaaggggagc tcatatgcgc aaagaggttc aggaatatat tttagcaaac 1568101 gaagaacgga aacgattcat cagagaacag ccgatatggt accgcaggct ttcaagaaaa 1568161 ccggatgatc tgtcctcctt tcagcttgaa atgatgaatt tttatgaaaa aaccattccg 1568221 catcgggtga atcagtttac gaacgggatt caaatggcgc aaatgatgat gcaaatgttt 1568281 caagcgatgc ggacaaaaga ttaaaaggcc ccgaagaagg gtcttttttc atgcggtcat 1568341 aaggttttgt tggcggctgc ggttaagcat tttccaattg gctggtttca tggtaaacta 1568401 acaactggag gtgcatgtta tgtatgcgac gatggaatcc gtgcggcttc aaagtgaagc 1568461 tcagcagctt gccgagatga ttctgcagtc ggagacggct gagaactacc gcaattgtta 1568521 caagcgtctc caggaagatg aagaggcagg tcggattatt cgttctttta tcaaaataaa 1568581 agagcagtat gaggatgtac agcgttttgg caaatatcat cctgactata gagaaatatc 1568641 ccggaaaatg agggagatca aacgtgagct ggacctgaac gataaggtgg ctgacttcaa 1568701 gagagctgaa aatgagctcc agtccattct tgatgaggtc agcgttgaga ttgggacagc 1568761 tgtttcggag catgtgaaag ttccgactgg gaacccttat tttgacggtt tgtcttcatg 1568821 cggaggcggc tgcggttcag gcggaagctg cggatgtaaa gtgtcctgac gagactggcc 1568881 gtctcgtctt ttacatataa gagaaaacag gcaggtgatt gtattggaga ataggcgcca 1568941 gggcatggtt gtgtatctgc actccctaaa gcagagcaaa atgctgagga agttcgggaa 1569001 tgtgcactat gtatcaaaac gattaaaata tgtcgtactg tactgtgata tggaccaaat 1569061 tgaaaaaaca atggacaaga ttgcgtctta ctcatttgtg aaaaaagtgg agccttctta 1569121 taaaccgttt ttaaaattgg aattcgagtc aaagcttgat aaggcaaaag aatacgatta 1569181 taaaatcggc atatagctat aaaaaaatcc ccgcaggcat ctgcggggtc cttctattcc 1569241 ttaatatgtt aaggagaagg caaagggaga ggagaaaccg gaggaagaac ttatggggaa 1569301 acgtaagtct tctccgcggt tggcaacaac atcctctaga tgctgttgct tatagtatgg 1569361 acaaggatca tgctgcctat acacctgttt atcaagatta gcgttcattg tttggaagaa 1569421 tgctttatgt taagatagga ttgatttttt tctatgtaca tagcggcgtc cggccgaata 1569481 aagaaacaaa atagctttta gaaaaagtgg tgtggaacat gagagtaatt tctggatcaa 1569541 aaaaaggccg ttcactaaag gctgtagccg gaacatcaac aagaccgaca accgacaaag 1569601 tgaaggaatc cattttcaat atgatcggcc cttattttga cgggggcagg ggacttgact 1569661 tattcgcagg gagcggaggt cttggaatcg aagcgctttc acgcgggttt gagcattgta 1569721 tattcgttga ccgtgatttt aaagcgattc aaacggtaaa atctaatttg aaaacgctgg 1569781 agcttacaaa acatgcacag gtataccgca atgatgcgga acgtgctttg cacgctgctg 1569841 ctaaaagaga aaccggcttt cgcggaattt ttctcgatcc gccgtataag gaacaaaagc 1569901 tgaaagcact tttaactttg attgacgaat atcaaatgct ggaagaagac ggctttatcg 1569961 tcgctgagca tgacagagag gtcgagcttc ccgaaaccgt aggagatctt gtgatgacaa 1570021 gaaaagaaac ctatgggtta acaggtgtag cgatttataa aaagaggggg tagtgaggtg 1570081 gcgagtatag ctgtctgtcc cggcagtttt gatcctgtga cctacgggca tctggacatc 1570141 atcaaacgcg gggcgcatat ttttgaacaa gtgtatgtat gtgtgctgaa taattcttca 1570201 aaaaagcctt tgttcagtgt ggaagaacgg tgtgagcttc tgagagaagt cacaaaagac 1570261 attccgaaca taacagttga aacatcgcaa ggcctgttaa ttgattatgc aaaaagaaaa 1570321 aatgcgaaag cgattttaag aggcttgaga gctgtatctg attttgaata cgagatgcag 1570381 gggacatcag taaaccgggt gcttgatgaa tctattgaga cgttttttat gatgacaaac 1570441 aatcaatatt cgtttctaag ttcaagcatc gtaaaagaag tggcaagata caacggctcg 1570501 gtatcagagt ttgtaccgcc ggaagtagag ttggcgcttc agcaaaaatt cagacaagga 1570561 tgagggtttt gactcatcct ttttttgttc cgtttgtcag tctgtaagaa aaaatgataa 1570621 tgtacgtaaa cagcgcgcat agtgtgacag caggtccgat ctgcacaagc agattccagc 1570681 cgtttataaa ggcagttgac atgtcactgc tgttaagaga tttaaataca tactgatacg 1570741 gatcatgcca tgctgtgtaa agaggtttcc ataaaagcat gacgaagaca gcggcataaa 1570801 cgccctgcag caaacgtgcg ataaagaatg gtttaaatct aatgtcggtt tccgataaaa 1570861 tacctgccac ctgagcttgt acggaaaagc cgctaaaccc aagaataaag ctgacgataa 1570921 tggctttttg cagaagagaa acatctgtct cgctgacaag cttgctgcct aatgtaattt 1570981 caaacatccc tgataaaagc ggaatgtcca attgagtcgg aagctgaaac aaagtcagtg 1571041 ctccttttgt gaaaacagac aaaacatcag tcagctggac cactgacaac agccgattga 1571101 agacagaaaa taaaataata aagccgccta ccataagaag cgtttgaaca gaagacgtca 1571161 cggcgtcgcc taaaatttta cctaagggcc gtttttctgc aagtctggcg gtatgaagag 1571221 cgtgtaaagc atctttgact gaagggaaag gtatcgtttt ctttcttctg agatgctgct 1571281 cttccttgcg gccataggag cgcattgtta aaccgacggc aagattcccc aaatagtgtg 1571341 cagaagctaa taaaatgcct agtgatgcgt tttgaaagaa accgacggca acagcgccga 1571401 aaataaagag cgggtttgaa gaattggtaa acgacgcgag ccgttctgcc tctactcttg 1571461 aaatctgatt ttcctgccgc agacgggcag tgagttttgc gcccgctggg tttcctgatg 1571521 ccattcccat agcaagaacg aagccgccga cacccggcac gcgaaagatc ggccgcataa 1571581 aaggctcaag caaaacaccg acaaaccgca caatgccaaa gccgattaag agttcggaca 1571641 gaataaaaaa tggcagcaat gacggaaaca caacctccca ccacatagac agcccggttt 1571701 tagaggcttc gaatgaggcc tgtggatgtg agatgacagt cgctgttaaa aaaagaaaaa 1571761 acgaggcaat caaaagtgta ttaatcttcg acaagttcat tcttacctcc ccgatgctaa 1571821 aaatgcccaa tgacatgtat atcatgataa aataatgtat gatgtaaaac ggccaagcag 1571881 tacctgtcct cttgattctt tgtactaata tacgagcata ggggttcagt ttagaccata 1571941 gaattcggta tacagggaat tcaggcagga ggttaacgct ttggccaaac ctaaaatcgg 1572001 gttagcgtta ggatcgggag gggccagagg gcttgctcat ctcggtgtgc tttccagttt 1572061 acataagcac caaattgaag tggatatgat tgcaggaagc agcatgggcg ctttggtggg 1572121 cagtttttac gccgccggac atgacgtggc aacgatgaaa aaagtagcca aagcctttaa 1572181 acgaaggctt tatgctgatt atacggtgcc gaaactcggt tttttaaaag gtgaccgcgt 1572241 cagacagctt gtgcatgctt atacattcgg aaaaccgatt gaagagctcc aaatcccgct 1572301 gggcattgtt gcgtgtgatc tacagacggg agaaaagatt gtgttccgaa aaggatcagt 1572361 gtcagatgca gtgagggcca gcatcagcat cccgggtatc tttattccgc agcggctgga 1572421 cggacgcctt cttgtagacg gcgcggtcgt cgatcgaatt ccggtttctg ttgtgaaaga 1572481 catgggagct gatattatca tcgcttcgga tgtttccagg gttcgaaaaa ctgaaacagc 1572541 agtgcatatt tttgatgtga ttatgcaaag tatggatata ctgcaaaatg aattagtgcg 1572601 gcatcaaaca attgccgcag atatcatgat tcgcccttcc cttgaaacat acagctcaag 1572661 ctcgtttgcc aatattgaag aaatgatatc ggcaggcgaa gaggcgacaa accgaatgat 1572721 cagcaagata agaaaagaaa tagagaattg ggagggctca taatttgcta cgtaaaaaac 1572781 attttagctg gatgctcgtc atcctcatac tgatcgccgt tttatcattt ataaaacttc 1572841 catactatat tacaaaaccg ggagaagcga cagagcttgc ttcattgata aaagtggagg 1572901 gaggctaccc ggaaaaagga agtctgtcct taatgactgt taaagtggga ccggctaatc 1572961 catttacata tgtgtgggca aagatgcacc cttattatga aattgttcct gatgagagca 1573021 ttaaggagga aggcgaatca gataaggagt atatgaaaag acagctccaa atgatgaaaa 1573081 gctcgcaaga aaatgcggtt atagccgcct atcaaaaggc aggaaaaaaa gtcagctatt 1573141 cctttaacgg catatacgca agctcagttg tagaaaacat gccggcaaaa gggaaaatag 1573201 aagtcggtga taaaatcatc agcgcagacg gcaaaaacta tcagtctgct gaaaagctga 1573261 ttgattatat cagcagcaaa aaagcgggag ataaagtcac gttaaagatc gaaagagaag 1573321 aaaaagaaaa gcgtgtcacc cttacgttaa aacaatttcc tgatgagccg gatcgggcag 1573381 gaatcggagt ttcgctttat acagacagaa acgtgaaggt agagcctgat attgattttg 1573441 aaatcgaaaa tattggcggc ccgtcagcag ggttaatgat gtcccttgaa atctataatc 1573501 agctgacaaa accagacgaa acaaaaggct acgatattgc gggaacaggt acgattgatg 1573561 ttgacggaaa agtaggcccg atcggcggca ttgatcaaaa agtcgtcgcc gcagacaaag 1573621 ccggaaaaga cattttcttc gcgccaaatc aaaacggcgc cagcaattcc gattataaga 1573681 acgcagtaaa aacagcaaaa gatattgatt caaatatgaa gattgtgcct gttgatacca 1573741 tgcaggatgc gattgattat ttgaataagc tgaaagcgaa aagcacctga ttctcaggtg 1573801 ctttttctat acatttaaaa agtgttgttc atcttcgtca tatcgaatcg gtgcatgtcc 1573861 gtattcctgt aggtcaaact cagttctcag cggctcttct atcggcaggc tgtaaatcct 1573921 gcttgctttt acgtccagat cgagagctgg atgggagaaa gaggacagtt tgctgacaag 1573981 cggaacagac agtgcttttt tcttttcgga taaataagcc tgtccttttt tcgtcatgcc 1574041 gagaagcctg atatacggcg ccttatcgtt gtcaagcagc ttttgcatat cctgtttttt 1574101 tgttctggtt aaaatgtgtg tattcatccg ctggagcctt gtccacgtat agcgttttgt 1574161 tttcagcagt tccataaatt cctgatagga gctggatttt ctgatcgaac gaataattct 1574221 gtgctctaaa ccttcctcca cctcgtatac ttgctgtaat tcccgtgccg ttacagttga 1574281 aaggctgtat tttaagtaag aaaagtagct ttcaggtgta tgccacaatc cgaaagattt 1574341 gcggtaagct gctaattcac gtgcagatgc agcagggaga aaacgaaggc aggcttcgag 1574401 attctggcca atcatcgctt ttctaatgct tgtggcactt gctatatggt tttcgccttc 1574461 agggagatcg gcatcatgat agtccgaaga gattcgtgcc gtagtataag gtttcatagg 1574521 atatcccccg gttagaatcg aggtcacata ctggtatccc aaaatgttat ttggttttga 1574581 caagtcaagt gcactttcag tatgcaaaat ggagctgaag gcgatagccg ccgctgctgg 1574641 gtaactggcc ccctttttaa gttcttcttt aattcggtca ttcaatatat gtttatgctc 1574701 atcaataagc tgtgctgttt ctaaaaaagg cttgatatcc ccattttcac tcccgaaaaa 1574761 cagcgcctca cattcaagtt cgttcaggat ggaaacactg ccgcgtgcaa aaatgtctgc 1574821 tttttgcacg gcataaagat aaggcagctc aatgacaaga tcaactccgc tttgcagcgc 1574881 catttttgtt cgggcccatt ttgatacaac agcgggttcc ccgcgctgta aaaaatgtcc 1574941 gctcatgacc gcgacagccg tgtcacatcc ggtttgcagc tttgctgttt gggcatgata 1575001 aaggtgaccg ttatgaaagg gattatattc aaccaccaat ccgacagctt tcatattttt 1575061 tccgcctttc ttgctatgtt taaaaacgta tggtacattt gcaaatgaaa actcttacgc 1575121 cttatttttg ttttaagtgt atgcatagca tattccgctg tcaacgatac ttcaatggca 1575181 gcattatgct gtaaagaaaa aatattgaca aaaacaatct taaaagctat aatcatgttt 1575241 gttgctttcc tgaggtgata caaatgaaat ggacgattta tcagctgcat caaatgccaa 1575301 aacaaagttt tgagtttgat gaaacagttg agttaaatga gctgacaaag ctgaattctg 1575361 acattcgccg catttctccc gttcgggtga agggcagagc ggatatcaaa tccaaacagg 1575421 tttcgtttga ttttacaatt tcaggcgaaa tgcttttgcc atgctcaaga acactcgttg 1575481 atgttccgta tccatttgaa atttcaacaa aagaactgtt tatatttcat cacacggatg 1575541 atatagaaga tgatgacgtt cacattgttg aggacgatac tatcgacata actccgatcg 1575601 tgaaagaaga aattctttta gaaatcccta tgcaaatctt ttgtgaatct gaacaagaaa 1575661 aaggagctgc tcctcaagaa ggaaaggatt ggcaagtcat ttcggaagaa gacaagaaga 1575721 atcaagttga tccgagactt gcagcccttg aaaagctctt aaaacaagat gatgaatctt 1575781 aactctttaa ggaggtggga ataatggctg taccttttag aagaacttct aaaatgaaga 1575841 aaagattgcg ccgtacacat ttcaaactta atgtacctgg tatgacagaa tgtccgtcat 1575901 gcggagagat gaagttgtct caccgtgtat gcaaagcatg cggatcatac aacggcaaag 1575961 acataaatgt aaaaagtaac taatgagaaa agcgcagggt gaaagccctg cgctttttct 1576021 ttttctcttc ctgtcagctt gcggaaaatt tgtgagtgca aatagtctat ctaatctatt 1576081 accggcatat gtatgagata aataagctga catggaggga gattgaattt gaccattaca 1576141 agacaagatg cttggactca ggatgaggat ttgctgctgg cagaagtggt gcttcgtcat 1576201 attcgagagg gaggaacaca gctttcagcc tttgaggagg ttggaagggc gctgaccaga 1576261 accgcggcag cctgtggttt caggtggaac tcgtatgtga gaaaacaata ccagtcaggt 1576321 atagagcttg caaaaaagca aaggaaagaa ctgagaaagc aaatcggcgt tcattcggtc 1576381 aatatgccga attccatgaa gcagactgcc tcggcatcgt cagaaggaaa acgagatttg 1576441 tccattcagg atgtcattca atttctcgaa caattcaaag aaacaccgtc tgcacaagaa 1576501 tttcagcttg aaagggaaaa attgaaggag caaatccaat cgctgcaaaa agagcttgag 1576561 gatttgcgga gtgaaaatca gacattgcgg aatcagctag agatgacaga agaggattac 1576621 aaggcactga tcgatatcat ggatcgggcc agaaaaatgg ttgtttcgaa ggaagacgga 1576681 agaatgaaaa aagcggctca agaaacgtaa agaaacgcct gaaatgaacc ggccctatag 1576741 taagaatagg ccggttgttt tgatttctat gcagactctc ccggtgtcat ttcgcgatcc 1576801 atatcaggat gccagatgag cgggttttcc cctttgtccc gcgccatatc atacttaaca 1576861 gttttaaagt tcattttgtt ccaaaattcc gctgatttca ttctcggatt tgtccggatc 1576921 ggcattttga atgattttgc aaattcaacc aaggctctcc cgtatcccct gttctggtag 1576981 cccggaagaa cctcaagctt ccacagctcc aaataatcct ggcggttgtc aaaataggga 1577041 ttcgatttgc cgttaacttg atacagactc attcgtgcta caagtttatc gccaaaataa 1577101 atcccgtaaa aaggcgaggt gctgtcattt tcaataatat tatcctgaag ttcttcaagc 1577161 attgaaagct cctgaatgcc gtattctttg aatttcttga attcttccag cgttttatag 1577221 ttgataagca gacgttctac ctttgtcaaa caaatctccc cctttgttgt ttctacatat 1577281 attgtaaacg ctttatttaa aaaatccaaa tatttaaact ttaattttaa gcacatggga 1577341 tctttgagaa gtaatttctt cttacttctg ctatgataat acgtaaatgc taaattgggt 1577401 gtgacatcat gaaaattgga attatcggcg gaggctccgt tggtctttta tgcgcctatt 1577461 atttgtcact ttatcacgac gtgactgttg tgacgaggcg gcaagaacag gctgcggcca 1577521 ttcagtctga aggaatccgg ctttataaag gcggggagga attcagggct gattgcagtg 1577581 cggacacgag tatcaattcg gactttgacc tgcttgtcgt gacagtgaag cagcatcagc 1577641 ttcaatctgt tttttcgtcg cttgaacgaa tcgggaagac gaatatatta tttttgcaaa 1577701 acggcatggg gcatatccac gacctaaaag actggcacgt tggccattcc atttatgttg 1577761 gaatcgttga gcacggagct gtaagaaaat cggatacagc tgttgatcat acaggcctag 1577821 gtgcgataaa atggagcgcg ttcgacgatg ctgaaccaga ccggctgaac atcttgtttc 1577881 agcataacca ttcggatttt ccgatttatt atgagacgga ttggtaccgt ctgctgacgg 1577941 gcaagctgat tgtaaatgcg tgtattaatc ctttaactgc gttattgcaa gtgaaaaatg 1578001 gagaactgct gacaacgcca gcttatctgg cttttatgaa gctggtattt caggaggcat 1578061 gccgcatttt aaaacttgaa aatgaagaaa aggcttggga gcgggttcag gccgtttgtg 1578121 ggcaaacgaa agagaatcgt tcatcaatgc tggttgacgt cattggaggc cggcagacgg 1578181 aagctgacgc cattatcgga tacttattga aggaagcaag tcttcaaggt cttgatgccg 1578241 tccacctaga gtttttatat ggcagcatca aagcattgga gcgaaataca aacaaagtct 1578301 tttgagcttt ttcggtaaca tgctatactc atttcggatc actaactatt tattggagaa 1578361 aggaagttct agaagatgca gctaactgaa ctttccatca aaaatcagaa tgtgtttgta 1578421 cagcactata tagatggcaa agaagaaatg tcttcttttt ttgattacag tattcatcat 1578481 aaggacatgt ggcgcgaaag actggaagac ttatcttccc ggtttttcgc aagagaggaa 1578541 ttggcggcgt acttaacctc ttaccataat aaattcggtt caagtgcgat gcagtctgct 1578601 attgagaagc tgaaggaccc gtcaagtgcc gctgtagtcg gcggacagca ggcaggactt 1578661 ttaacaggac cgctttacac catacataaa atcatttcaa tcattgtttt agcaaagcaa 1578721 caagaaaagg aactgcaagt gcctgtcata ccaatcttct gggtggctgg agaagaccac 1578781 gatttggatg agattaattt tgttcacaca tctgaagaga atgggcctgt gaaaaaaaag 1578841 ctgcctcagt cttattggaa gaaatcatca gcagcgagta catcgcttga tcaggaaaag 1578901 tgtgccgcgt ggatagatga tgtttttgcc gcttttgaag aaacagacca tacgaataca 1578961 cttctcgaca atgtgaaacg atgtttaagg gaatctgtta cgtttactga cttctttgaa 1579021 ctgctgatcg cggatttgtt ccaagaagag ggcttagttt tattaaattc tggggatccg 1579081 gggattaaaa agctggaaac ggccatgttc caaaagattc ttcgagaaaa tgatgaactc 1579141 gcccgggctg tatcagatca gcaggccttc atgcgtcaag caggctacaa accgattatc 1579201 gagtccggaa aagagcaggc gaatctgttt tatgaatacg aagatgagcg ttttttaatt 1579261 gaaaaagata acggccgatt tgtcatcaaa gagcttgatc taggatggac gagggatgaa 1579321 cttcatacac atatggaaga acatccagag cgtttcagca acaatgttgt aacgagaccg 1579381 ttaatgcagg aatttctcat tccgacttta gcatttattg cagggcctgg ggaaatcaat 1579441 tattggggcg agctcaaaca ggcatttgcg gtgatgggct tcaaaatgcc tcctgtcatg 1579501 ccaaggctga acattacgat acttgagcgg catattgaga aaaaactggc tgaacggaat 1579561 atctcattac aagacgcgat tgagcgcgga acggagaatc aaagagagac atacttcgag 1579621 cgccagattc cggaagagtt tacggcggtg atggatcagg cgaaaagcca aattgaagcg 1579681 attcacaaaa cggtccggca ggaggcgtta aaggttgatc aaagcttgga acctttactt 1579741 ctgaaaaatg ccgcttttat tcaggatcag cttcaattct tagagcgcac ggtgatgaag 1579801 cgaattgaag aaaaagaagg ctacgtcttg aaggattatg aaagaattca aaatagcatt 1579861 aagccgcttc ttgcgccgca agaacggatt tggaatatca tgtattattt gaacaggtac 1579921 ggtccaaaat tcttcacgac attcaagaat ctgccatttt cttttcaaaa tcaacatcaa 1579981 gttgtcaaac tttgaaataa agttttaaag aaccctgact agttcagggt ttttttttat 1580041 gggtaaacag tgtaaaatga agttgtggag cgaagtggtg aatagtggtg agttaaggag 1580101 agaaagtggg gcaagagatc atgtttatgg gtgaatatca gcataccatc gatgcgaaag 1580161 gccgcatgat cgtacccgct aaattcagag aaggcctagg tgagcaattt gtgctgacta 1580221 gaggacttga ccaatgtctc ttcggctacc ctatgcacga atggaaacaa attgaagaaa 1580281 aactaaaagc tcttcctctc acaaagaaag atgcccgcgc gtttacccgt ttcttctttt 1580341 caggggcgac tgaatgcgaa ctggataagc aaggcagggt aaatatcgca tcatctctat 1580401 tgaattacgc caaactggaa aaagaatgtg ttgttatcgg ggtttctaat cgaattgaat 1580461 tgtggagtaa agtaatttgg gaacaataca cagaagagca agaagattca tttgctgaaa 1580521 ttgctgaaaa catgattggg tttgatatat aatgattctt cgtgtataac actctaaaaa 1580581 caatttcaat tcatcctgat aaaaggtggg accaacacaa tatgtttcaa cacaagacag 1580641 tacttcttcg tgaaaccgta gacggactta atattaaacc agacggtaca tatgtagact 1580701 gcacactcgg cggagctggg catagtacat acttattgca gcagttatcc gagaaggggc 1580761 gtttaatcgc ttttgaccaa gatgatacgg cattacagca tgctaaagaa gtgttgtccg 1580821 attataaagg acagctcatt ctgattaaaa gcaatttcag gtatttaaaa gaatatttga 1580881 atgaacaagg cgttacagaa gtagacggca ttttatttga tttaggggtg tcctctccgc 1580941 agctggatac accggagcgc ggattcagtt accatcatga cgcaccgttg gacatgagga 1581001 tggaccagtc ggctacgctt tcggcgaaag aagtcgttaa tgagtggcgc tatgaggatc 1581061 tcgtccgtat tttctttaaa tacggagaag agaagttcag taaacagatc gccagaaaaa 1581121 ttgaggaggc aagaatgaag tctcctattc aaactacggg ccaactggtc gatctaataa 1581181 aagacgcgat tcccgctcca gcgagaagga gcgggggaca tcccgctaaa cgcgtgtttc 1581241 aggcaatcag aattgccgta aacgatgaac ttagggtgtt tgaagaagct ttggagcagg 1581301 caattgaggt tctgaagcca gggggcaggg tatcggtcat taccttccac tcgctagaag 1581361 acagaatttg caaaaccact tttaaagaaa agtcgtcgct tccggaactt cctccgggac 1581421 ttcctgttat accggaagag tttgaaccgg agctgaagct catcacacga aaaccgatta 1581481 cggcatctca agaagagctt gaagagaaca accgggctcg ttctgccaag cttcggattg 1581541 ctgaaaaaag aaaataacga aacgcgaacg caaaattaaa aggaggtcat cagcctatga 1581601 gcaatttagc ttaccaacca gagaaacagc agcggcatgc gatcagtcct gagaaaaaag 1581661 tgattgtcaa gaaaagggct tccattactc tcggagaaaa agtgcttctt gtcctctttg 1581721 ctgcggcggt gctcagcgta tcgcttttga tcgtatcgaa ggcgtatgcg gcatatcaaa 1581781 ccaatattga ggtgcaaaag cttgaggagc aaatttcatc cgaaaataag caaattggtg 1581841 acctcgaaaa aagcgttgct gatttaagca aaccgcagcg cattatggac attgcgaaaa 1581901 agaacggctt gaatttaaaa gataaaaaag tgaaaaacat acaggaatga ttcaaatgcc 1581961 aaaaaagaat aaatttatga atagaggagc agcgattcta agtatttgtt tcgctctctt 1582021 tttctttgtc atcctgggga gaatggcata tattcaaata accggaaaag cgaacggcga 1582081 agtgcttgcg acaaaagcga cagagcagca tgaaaagaaa cggaccatcg aagcgagccg 1582141 cggctcgatt ttagaccgaa aaggaaaagt cattgcagag gacacagcga cgtataaact 1582201 gattgcgatt ctcgataaaa aaatgaccac tgatgtcaag catcctcagc atgttgtaaa 1582261 caaagaaaaa acggcggaag cattgtctaa agtgataaac ttggacaagg ccgacatcct 1582321 tgatatctta aataaagatg caaaacaagt cgagtttggc tcagctggcc gggatattac 1582381 gtattcacaa aagcaaaaaa tcgaaaaaat gaaactcccg ggcatttcat ttttacggga 1582441 tacaaaacgc tactatccaa acggagtatt tgcatctaat ctaatcggct atgccgaggt 1582501 tgatgaagaa acaaatgaaa tttccggcgc gatgggatta gaaaaagtgc tggataagta 1582561 tttgaaggag cgggacggat atgtgacata tgaaagcgac aaatccggct gggagctccc 1582621 gaacagcaaa aataaaatta cagcgccaaa aaatggtgac aatgtatatt taaccattga 1582681 ccagaaaatt caaacctttt tggaagacag catgacaaaa gtggcgcaaa agtataatcc 1582741 gaaaaaaatc atggccgcag tcgttgatcc gaaaacgggc aaagtccttg ccatgggaca 1582801 gcgcccaagc tttgatccga acaagcgcga tgtgacaaac tactataatg atttgatttc 1582861 atatgcgtat gaacccgggt ccacgatgaa gatctttaca ctcgctgctg cgatgcagga 1582921 aaacgtgttt aatgcgaacg aaaaatataa atcagggaca tttgaagttg gcggagcacc 1582981 tgttaaggat cacaataacg gtgtaggctg gggtccgaca acatatcatg acggcgtcct 1583041 aaggtcgtcg aatgtcgctt ttgcgaaact ggcgaaagaa aagctgggat atgaccgcct 1583101 caatcaatat ttgcacaaat tcaattttta ccagaaaaca ggtattgatt tgccaggaga 1583161 agtctccagc aaaatcaact ttaaatatga atttgataag gcgtcaactg catatggcca 1583221 agcgtctgcg gtcacaccaa ttcagcagat tcaggccgca acggcaattg caaatgacgg 1583281 taaaatgatg aaaccttatg tcattgacca tatcgttgac cctgataaag ataaaactat 1583341 ttatcaaaat aagccggaat cagccggaac tccaatttct gcaagtactg cgaaaaaggt 1583401 gcgggatata ttaggagaag tcgttacatc gaagatcgga acagggcaag cttataaaat 1583461 cgaaggtttt gatgttgccg ggaaaacagg tactgcgcaa atagccggta aaggcggata 1583521 tttagacggc acagataact atatcttttc gtttatgggt atggcgccaa aagatgatcc 1583581 tgagctttta atttatgttg ctgtacagca gccgcaacta aaagcaggac aaagcagttc 1583641 agatccagta tcagaaatct tcaatccaac aatgaaaaat agcctgcact acctaaacat 1583701 cgaaccaact gaaaaatctg actcagataa ggaagaaaca aaagcgcaga caatgcctga 1583761 tttaacagat caaacggtag ctgctgctca aaagaaagca aaagaggaga atctcacacc 1583821 aattgtcatc ggcagtgatg tcgctgtaaa agaacagtat ccgaaagcgg atgaggaagt 1583881 tctcaccaat caaaaggtct tcctgaaaac gggcggcaaa atcaaaatgc ctgatatgac 1583941 aggctggtcg agaagagagg ttctgcagta cggcgagctc gcgggaattc atattgaagt 1584001 aagcggacaa ggctacgctg tcagccaaag tgttaagaaa gacaaagaaa tcaaagacaa 1584061 aaccgtaatc aaggttaagt ttaaaaatcc tgattaaaaa gaaagccgtc gttatgcagg 1584121 ctttcttttt ttatgccttc agaggagcat cgttctacct gtccaaattc aggcataaaa 1584181 tgaaacaagc ctaaataagg agtgaacggt ctcttgcgcg tctcgaatgt aacggttaga 1584241 aaacgtttat tatttgtttt gctttttggc gtgatcgtgt ttctgatcat tgatacaagg 1584301 ctggggtatg ttcagtttgt gatgggcgaa aaactgactt cgctagcgaa agattcctgg 1584361 agccggaact tgccgtttga gccggagaga ggcgagattc tggatcggaa tggtgtgaag 1584421 ctcgcaacaa ataaaagtgc gccgaccgta ttcgtcgtgc cgcgccaagt tcagaatccg 1584481 atgaaaacga gcaagcagct tgcggcggtg ctcaatatgt cagaagaaaa agtatataaa 1584541 catgtgacaa aaaaagcgtc aatcgaaaag atcactcctg aagggagaaa aatttcaaat 1584601 gagaaggcga aagaaatcaa agcgcttgat ttaaaaggtg tgtatgttgc ggaggacagt 1584661 atccgtcatt acccgttcgg cagcttttta tctcatgtgc ttggatttgc aggaattgac 1584721 aaccaagggc tccttggact tgaagcctat tacgacgatg atttaaaagg ggaaaaaggt 1584781 tctgttaagt tttatacaga tgccaagggg aagaagatgc ctgatgaagc ggatgactat 1584841 acgccgccta aggatgggct tgatatgaag ctgacagttg attcaaaggt tcagacgata 1584901 atggaaagag agcttgataa cgctgaggcc aaatatcatc cggacggcat gattgccgta 1584961 gccatgaatc cgaaaaacgg agaaattttg gggatgtcta gcaggcctga cttcgaccct 1585021 gctgattacc aatctgttga tccgtccgtc tacaatcgaa atctgccagt atggagcacg 1585081 tatgaaccgg gatctacctt taaaattatt acacttgcag cagcccttga agagcaaaaa 1585141 gtaaatttga aacgggatca attttatgat aaagggcatg ctgaagtgga cggagcgaga 1585201 ctgcggtgct ggaaaagagg cgggcacggg ctgcagacgt atctggaagt tgtgcagaac 1585261 tcctgcaacc cggggtttgt tgaattaggc gagcgcttag gaaaggaaaa gcttttcaaa 1585321 tatatcaaag actttggttt tggacaaaaa acggggattg atctccaagg cgagggaaca 1585381 ggcatcttat tcccgcttga gagagtgggc ccggtggagc aagcaactac ggctttcgga 1585441 cagggagtat ccgtcacgcc gattcagcag gttgcagcag tatccgccgc tgtaaacgga 1585501 ggaacgctct atacacctta tattgcaaag gaatggatcg atcctgttac gaagaaaacg 1585561 gtcaaaaaac aatcaccaat cgcaaagaaa caagtcattt ctgaggaaac atccaaacaa 1585621 atccgctatg ctctagaaag cgtcgtcgca gaaggaaccg gccgcaatgc atttgtagaa 1585681 ggatatcgtg tcggaggaaa aacgggaact gcacaaaagg ttaaagatgg aaaatatctt 1585741 gaaaacaacc atattgtatc atttatcggt ttcgcgccag cagatgatcc gagtctagtc 1585801 gtctacgttg cggtggataa cccgaaaggc acgattcagt ttggcggaac ggtggcagcg 1585861 cctattgtcg gaaatattat gagagacagt ctgccggaac ttggtgtgaa gccccggaaa 1585921 aatcaaatcg agaaaaaata ccaatggaac gacacaaaaa caatagaagt tccgaatgtt 1585981 gtagggatgt ctgtctcaga tcttgagtca ctattggtga atctcaatgt ggatgcttcc 1586041 gggaaaggga gcaaaatcgt taaacaatcg ccagctgccg gaacgaaagt aaaagaaggc 1586101 tcaaagatac gcgtgtattt gactgaagaa gatgaaaagg aggcagccga ttgattcggg 1586161 ctgcctattc ttttattgca gaaaaaatgc tgatatcttt caagattagc tggatgtatc 1586221 cttttattta cgctaaaata tgaactgtat gcttaaaatc attaccacat catttgatgt 1586281 gacttcaatg ataaaaagaa cgaattagaa tgttgagagg tttgatacga tgaaacttac 1586341 aaagctgctt acatacttaa caaccgaacc ttctgtaaac gactcacaag accctgaaat 1586401 aacttcaatt gagatggact ccagggaagt aaagaaaggg agtctttttg tatgtgtaaa 1586461 agggtatacg gtggatggcc acgattttgc gcaaaaagca gtagaaaacg gtgcagcggc 1586521 tattgtggca gaaagagagg tcgatgtgaa tgttcctgtt attattgtcc ggcagtcact 1586581 tcgcgcgctc agcgttttgt ctgatgcgtt ttacggacag ccgacgaaga agcttcagct 1586641 gattgggata acagggacaa acggcaaaac atcaacgacc cacatggtcg atgagattct 1586701 gaaaaaagcg ggaaaacgca caggcttgat cggtacaatg tacatgaaaa tcggagacga 1586761 aacacttcct gttaaaaaca cgactccgga aagcgtcacg ctgcagaaaa cgtttaagaa 1586821 aatgaatgac aagcacgttg acactgcaat catggaggtt tcttcccacg ctttgtcttt 1586881 aggacgcgtc catggctgtg attatgatat tgccgtgttt acgaatttaa cacaggacca 1586941 tctggactat cataaaacga tggatgagta ccggcatgca aaaagcttgc tcttttccca 1587001 acttggcggg gctttcaacc atgaacatcc aaagcgtgcc gtcctgaatg ctgacgatga 1587061 ggcgagcgct tattttgaaa aggtaacagc tgcgcatatc tctacatacg gaattaaaaa 1587121 cgatgctgat gtgatggcga agaacatcag tatcactgca cagggcacaa gctttgatct 1587181 cgtgacaaac aaaggcacga agcacatcac gatgtctctc gtcggacaat ttaatgtgta 1587241 taacgtgctg gccgctgttg cgacatgtat tgcagcaggc ataccgtttg aaatcatcac 1587301 tgaggctgtt gaagaattgc atggtgtaag aggccgtttt gaattggtca atcagcagca 1587361 ggagtttcct gtcattgtag actacgcgca cacaccggac agccttgaaa atgtgctgga 1587421 gacatgcaga gacatgacgg aaggaaagct atttgtcgtt gtcggctgcg gaggagacag 1587481 agataagacg aagcgcccga aaatggctaa aattgctgtg gagctggctg acgagccgat 1587541 tttcacgtca gataacccga gaagcgaaga tcctcgcgcg attttaagag atatggaagc 1587601 cggagtagag aacgcatact atcacagtat tgcaaaccgc gagcaggcga tctttttcgc 1587661 aattgccaat gccaaaaaag gcgacgttgt cctcattgcc ggaaaaggac atgaaaccta 1587721 tcagcagatc ggaaatgaaa ctttcgattt tgatgatgct gaagtagcgg cgagagccat 1587781 tgttgaactc aataagaata agacgaattc ataggaaaga gatgttactg aataatggag 1587841 cttgaaaaga tttttcatat ggaaaaaaat catgaatatg ataactacgt atgtcgtttg 1587901 aaagaaacag gaggagaaaa ggacaatgct tgagcaagtc attctgttta caattttaat 1587961 ggggttttta attagtgttc tgctctctcc gattcttatt ccgtttttaa gaagattaaa 1588021 attcggccag agtattagag aagaaggacc gaaatcacat cagaaaaaat cagggacacc 1588081 gacaatgggc ggggtcatga tcatactttc tatcatagtg acaacaattg ttatgacaca 1588141 gaagttttca gaaataagcc ccgaaatggt gctgcttctg tttgttacgc taggctacgg 1588201 tttgcttggc tttttagatg attacatcaa ggttgtcatg aagcgcaatc ttggattgac 1588261 atcaaagcaa aagctgatcg gacaaattat tattgcggtt gtattttacg ccgtgtatca 1588321 ttactacaat tttgcgacgg atattcgcat tcctggaact gacttatcat ttgatcttgg 1588381 ctgggcttac tttatccttg tgctctttat gctagtcggc ggatcaaacg cagttaacct 1588441 gactgacggc cttgacgggt tattatccgg tactgcggcg attgcctttg gcgcctttgc 1588501 cattctggca tggaatcagt ctcaatatga cgtagcgatt ttctcagttg ccgttgtcgg 1588561 tgcagttctg ggcttccttg tatttaatgc tcatccggcc aaagttttta tgggagatac 1588621 gggatcgctt gcattgggag gagccatcgt taccattgcc attttaacga aattagagat 1588681 cctgctggtt atcatcggcg gtgtattcgt tatcgagaca ttatccgtta ttttgcaggt 1588741 catcagcttt aaaacgacag gtaaacgaat ctttaaaatg agtccgcttc atcaccatta 1588801 tgagcttgtc ggctggtctg aatggagagt agtcgtgacg ttttgggctg cgggactttt 1588861 gcttgccgtt ttaggaattt acatcgaggt gtggttataa gtggaaaatg atcaattttt 1588921 acagaaacag cattttttaa tccttgggct tgcgaaaagc ggatatgcgg cggcctccat 1588981 tcttcatgaa aaaggcattt atgttgcagt caatgatcaa aagccttttg aagaaaatga 1589041 accggcacaa aagctttctg aaaaaggaat cgaagttgtt tgcggagagc atccagtttc 1589101 tctgttcgat cagcatcaaa tcacgattct gatcaaaaac ccgggaattc cttatgaaaa 1589161 tatcatggtt caggaagcag agaaacgagg tattccggtt tggacggaaa ttgagctcgc 1589221 ttactacctg accagcgcca agtttatcgg gattaccgga tcgaacggta aaacgaccac 1589281 gacaacgcta atttacgaaa tgctcaaggc tgactcgcaa aaagcactga ttgccggaaa 1589341 catcggcaca gtcgcaagtg aggttgccta tcatgctgat ggagatgaat ggatcgttac 1589401 cgaactgtct tcgtttcagc tgatgggaac acacgctttc agaccggaaa tcagcctgat 1589461 tttaaatgta tttgacgccc atctggatta tcaccatacg cgcgaaaact atgaaaaagc 1589521 gaaacagaaa gtgtaccttc atcagactgc ttcagataaa gctattgtca accaggatga 1589581 tgaaaccgtc gtgcgtcttg ctgaagccgg aaaagccgaa atcgtcccat tttcagtcag 1589641 caaaacgctt gaacagggcg catatgtaaa agacagtatg attatgttta acggcgaagc 1589701 cattcttcct ctggaagagg ttgtactgcc cggtgctcat aacctggaga acattttagc 1589761 agctattgca gttgtgaaaa cggcaggagc atccaatgag gcggttaaaa aggtgctgac 1589821 aagctttact ggtgtgaagc accgcctcca atatgtcaca actgtgaatg gccgcaaatt 1589881 ttataacgac agtaaagcaa caaacattct ggcgacaagc aaggcgcttt cagcttttga 1589941 taagccggtc attctgcttg cgggcggact ggatcgcgga aatggttttg atgacttgaa 1590001 accttatatg aagcatgtca aagcagtgct tacatttggc cagacggcgc caaaactcga 1590061 gaaactcggc aatgaactgg gaatacaaca tgtcaaacgt gtcgataatg ttgaacaagc 1590121 agtatctgcg gcgtttgcgc tctcaaatga aggagatgtc atcctgctgt cacccgcgtg 1590181 tgcgagctgg gatcaattca aaacatttga agaacgcggt gacatgttta tagatgccgt 1590241 gcatatgctt aagtaagggc ttgtcttgaa gtaaatcggc agccctaatg actttaagct 1590301 tggggtgtcg attgctttga ctactaaaaa aacatcgcct gatttgttat tggtcatcat 1590361 tacgttatta ttattaacaa tcggattaat tatggtgtac agtgcgagtg cggtatgggc 1590421 ggattataaa tttgacgact cattcttttt cgcgaaacgg cagcttttgt ttgcgggaat 1590481 cggcgtcatt gctatgtttt ttatcatgaa tgttgattat tggacttgga ggacatggtc 1590541 caaattgctg atggttatct gctttttcct tctggtgctt gttttgatac cgggcgtcgg 1590601 aatggtgcgg aacggttcaa gaagctggat cggagtcgga gcattcagca tacagccttc 1590661 agagtttatg aagcttgcga tgattgcatt ccttgctaaa tttctctctg aaaaacaaaa 1590721 aaacatcaca tcgttcagac gggggttcgt ccctgcactt ggcatcgtgt tttcagcatt 1590781 tttgattatc atgtgccagc ctgacctcgg aacggggaca gttatggtcg gaacttgtat 1590841 tgtcatgatt tttgtagccg gcgcacggat cgcccatttc gtctttctcg ggctgatcgg 1590901 cctcagcgga tttgtcgggc tcgtactatc ggctccatat cggataaagc ggattacctc 1590961 atacttaaat ccatgggaag acccgctcgg aagcggattt cagatcattc aatcgcttta 1591021 tgcagtgggg cccggcgggt tgttcggaat ggggctcgga caaagcagac agaagttctt 1591081 ttatctgcct gagccgcaaa cagactttat tttcgccatc ttgtcagagg agctgggctt 1591141 tatcggggga acacttattt tgctcctctt cagcgtcctg ctgtggagag gaatcagaat 1591201 tgcgcttggt gcgcctgatc tgtacggaag ctttgtcgca gtcggcatta tttcaatgat 1591261 tgccattcaa gtcatgataa atatcggcgt agtcacgggc ctgattcctg taacaggcat 1591321 cacgctcccg tttctgagct acggaggctc ttcattgact ctaatgctga tggcagttgg 1591381 tgtgctgctg aatgtaagcc gctactcgag gtattaacga atgtatttcc aagcctcctg 1591441 tctaacatga agcttggaaa caattgatgc gataaccctg tccaacaaaa cagggttatc 1591501 gttatgttat agagaaactt agactggggg aaaaaagaaa tgcgaattgc aataagcgga 1591561 ggcggtacag ggggacatat ttatcctgct cttgctttta ttaaagaagt gcaaagacgt 1591621 catcctaatg tggaattttt atatatcgga acagaaaacg ggctggagaa aaaaattgtt 1591681 gagcgggaga atataccgtt tcgttcaatt gaaattacag gatttaaaag aaaattgtca 1591741 tttgaaaatg tcaagactgt gatgcgtttt ctgaagggcg tcaaaaagag taaatcgtat 1591801 ttagcggaat ttaagcccga tgccgtaatt ggaacgggcg gttatgtatg tgggccggtt 1591861 gtctatgccg ctgcgaaaat gggaattccg actattgtcc acgaacaaaa cagcctgccg 1591921 ggcatcacga ataagtttct ttcaaaatat gttaataaag tagcgatttg ttttgaagaa 1591981 gcgaaatcac attttcctag cgagaaagtt gtatttacgg gaaacccgag agcctctgaa 1592041 gtcgtctcaa taaagacggg acgatcattg gctgaatttg ggctttctga agacaaaaaa 1592101 acggtcttaa ttttcggcgg aagccgaggc gctgcaccga ttaaccgcgc tgtcattgac 1592161 atgcaggatg tgctgaaaac aagagactat caagtgctgt atatcaccgg tgaagttcac 1592221 tatgaaaaag taatgaatga gctgaaaagc aagggtgccg ctgataatat ggtcacaaag 1592281 ccgtttcttc atcaaatgcc tgagtattta aaggccattg atgtcattgt ggccagagcc 1592341 ggtgcgacaa cgattgccga aattactgct ctcggaatcc caagtgttct gatcccaagt 1592401 ccatatgtga cagcgaatca ccaggaggtc aatgcgaggt ctcttggcca gcatgatgcg 1592461 gcgattgtac tgaaagaaac agagctcagc ggggagaagc tgattgaagc gctagaccgg 1592521 attgtactga atgagcaaac gttaaaggaa atgagcgaac gaacaaagtc actcggtgtt 1592581 cctgacgcgg ctgcccgttt atacagcgta ctcgaggaat taaaaaaata gtagaaaagc 1592641 aaatggaatg cggaggttta cgatggagaa agtgatacag gaattaaaag aacgagaagt 1592701 cggcaaggtt cttgcaaatg aaccgctcgc gaatcataca acgatgaaaa tcggcggacc 1592761 tgcggatgta ttggtcattc caagcagtgt ggatgctgtt aaagacatca tggacgtgat 1592821 taaaaaatat gatgtgaagt ggacagtcat cggccgcgga tcaaatcttc ttgttttaga 1592881 tgaaggaatt agaggcgtag tgatcaagct gggggcgggt cttgaccatt tggagcttga 1592941 aggggaacaa gtaacagtcg gaggcggtta ttcggtggtc cgccttgcta catcattgag 1593001 caaaaaaggc ctgtccggtt tggaatttgc tgccggcatt ccaggatcag tcggcggagc 1593061 ggtttatatg aatgccggcg ctcacggttc tgatatgagc gagatcctcg tcaaagcgca 1593121 tattttattt gaagacggaa cgattgagtg gctgacaaat gagcagatgg atttcagcta 1593181 caggacatct gtactgcaaa agaaacgccc gggcgtttgc cttgaagctg ttttgcagct 1593241 tgagcagaag gataaggaat caatcgttca gcaaatgcaa agcaataaag actatagaaa 1593301 aaatacacag ccgtattcaa gcccttgtgc gggaagcata ttcagaaatc cgcttccgaa 1593361 tcatgccggg aaccttgtag aaaaagcagg cttgaaagga tatcaaatcg gcggtgcaaa 1593421 gatatcggag atgcacggaa acttcatcgt caatgcgggg ggagcatcag caaaagatgt 1593481 gcttgatctc attgaccatg tgaaaaagac aatccgtgaa aaatacgaga ttgatatgca 1593541 cacagaggtt gaaatcatcg gcggaaatcg ctgattcaag ttctgactga agctgttcat 1593601 atgatatact gtaagcaaac gacaaacggc atcatagtat gccgtttgtt ttggaataga 1593661 cagactttta acagctgttt catttgaatg aggtgaacag gcaatgaacc cgggtcaaga 1593721 ccgagaaaaa atcgttaaca ttgaagagcg gatccctaaa attaaagagc agaggaaaca 1593781 aaaggcaaac cgccgtctca tttcatttat tatgctcttt tttattatgg tgctgatcat 1593841 tgtgtacctg caaacaccaa tcagtaaagt atcaacaatc tctgttacag ggaatgaaaa 1593901 tgtatcaaaa aaggaaatta tcgacctttc cgatattaac agcggagata ctgagttttg 1593961 gagtttggac aagcaaaaaa cagaaaagaa gattcagcaa aataaattag tgaaaaaagc 1594021 ggagatcagc aaatcgcttc ctaataaaat caacattgca atcgaagaat ataaagcgat 1594081 tgcttattta gaaaaagacg atgtgtacta tgaagtgctt gaaaacggct cagttctgcc 1594141 aaacgaagta acgccggatg atgccggacc gattttagtg aattggacaa acgcgaagaa 1594201 gcggtctcaa atggccaagc agctcgatgc gttgtcaaat tcgttaaaac agtcgatttc 1594261 agaaatttat tatacgcctg taaaaatgga tgaaaaccgt attaagttgt acatgaacga 1594321 cggttatgtt gttacggcat ctattaaaac gtttgcagac cgaatgaaga cgtatccttc 1594381 tatcatctca cagctaagca gcaataaaaa aggaatcatt catttagaag ttgccaccta 1594441 ttttgaagag tttgggaaaa acgataaagc tgctaaaaag gaagatgaaa attgaggggc 1594501 aaatcagcag tccttctttc cttgattatg cttatcgcag gttttttgat ttcattttct 1594561 tttcaaatga caaaagaaaa caacaaaagc gcggctgaga cggaagagtg gaaaaaagaa 1594621 tatgcgctga gagatgaact gctgaaacaa gagaaagaaa ataagaagtt tgaaaaagaa 1594681 ttatatcaaa agcaaaacaa agtccgccag gcggaaaata agctgaagaa agagaagtcg 1594741 gaatactata atgtcctcga agatacagaa aaatacagga tgtatattgg ggaagtcggt 1594801 gtgcagggag aaggcgttga ggtgacattg gaagatgcgt catacatacc ggaaggggag 1594861 aatgtgaata gttacatcgt tcacgaaagc catatcttcc aagtagtaaa cgaactgtat 1594921 atctcaggag cggcagctgt cgccgttaat ggacagcgtt tgacgcatga ttcgtatatc 1594981 aaatgcaatg gtcctgtggt aacggtagac ggggtgcagc atcccgctcc gtttacggta 1595041 tccgctattg gagatccaga tgtcctgctg ccctcgttaa atatcgctgg aggcctaatt 1595101 gatcagctgt caatggatca tatttctgtg tcggcagaaa aagagaaaaa cgtacaaatg 1595161 aaaccgattc tgaaaacgaa ggaatgactg aaaaagcggg tgaaatagat tgaaaataaa 1595221 gcgttccttc ataagcatca gtgttcttat ggtcatcttc ggcctgatga tatctgttca 1595281 gtttaattcg ttaaagcacc ccaaagtccg ggatacaaga gatatgtggg atattaggga 1595341 agagctgaca tcagagcaga agaagcagga aaagctgctg gctgaaataa acaaatatga 1595401 caaattgctg aatagctatt cgcaaacgaa agaaatgaca aaagaaaccg cgctaaataa 1595461 taccttgcaa tccttaaaaa aaacagccgg catgaccgat ataacaggta gcggaattgt 1595521 cattacgatt tccccgcttt tttctgaaag cttaacagga gagccgatcg aaaatccgcc 1595581 tccggatttg ctgaaaaagc tgataaatga actcaactcc tacggtgcag agcatatctc 1595641 gattaatgag cgaagagttg tgaatcatac agtcatcaga gatataaacg gcactacaaa 1595701 aatagacgga tacgcccttg acgattatcc tttaacagta aaagtgcttg ccaaagatcc 1595761 ggacatgtta cacagcagag tgaaggggtc aggccttgag gatctttttg catctgaaaa 1595821 tttagcatta aaagccggta aatctgaaag caaactaaca ttaaaagcat atgacagacc 1595881 actggacgta caacagctga aactgcttaa agactgaaaa ggaggagaat tgtcatgtgg 1595941 ctgcccgtgt tgggactggt gctcggaata gcgattggac taatgacaaa cttaacgata 1596001 ccgagtgaat actcaaacta tttatcgctt gcggtgcttg ccgcacttga tacattaatc 1596061 ggcggaatca gggcgcattt acaaggtaca tatgatgaaa tggtatttgt ttccggtttc 1596121 ttttttaata ttatattggc aataagttta gcttttctgg gagtccatct tggtgtagac 1596181 ttgtatttag caggtatatt cgcatttgga gtcagattat ttcagaatat agccgttatc 1596241 agaagaaatc tactaacaaa gtggactctt tctaaaaaaa ataaaaaaaa tgtgatataa 1596301 aagaggatat acataggata taacgaatat tttcaataaa cataaaatgt gaaaagcaca 1596361 taaaaatatt ctgttgttat tttttgttac acacttgtaa agccacattc attgtattgt 1596421 tgttccgcaa ataatagaat agaaatgatc gaaatgtgag gaggtgccat agaatgaaca 1596481 acaatgaact ttacgtcagt cttgacatcg gtacgtccaa tacaaaagtg atcgtcggag 1596541 aaatgacaga tgattccctt aatattatcg gtgtgggaaa tgtaccgtct gaagggttga 1596601 aaaaaggctc aatcgttgat atagatgaga ccgttcattc tataagaaaa gcgtttgacc 1596661 aagctgaaag aatggtaggt tttccgctta gaaaagctat tgtcggcgtt aatggaaatt 1596721 atatcaatat tcaagataca aacggtgttg tagcagtttc cagtgaaaat aaagaaattc 1596781 aggttgaaga tgtacgccgt gtcatggagg cggcacaggt tgtttccgta ccgcatgaac 1596841 agctgattgt tgacgtcatt cctaaacagt ttatcgtaga tggaagagat gaaatcaccg 1596901 acccgaaaaa aatgctgggt gtgcgtttag aagtagaggg caccttgatc accggttcaa 1596961 aaacaatctt acataactta ctccgctgcg ttgaaagagc tggtattgaa ataactgata 1597021 tttgccttca gccgctggca gccggttctg ctgcattatc aaaggacgag aaaaaccttg 1597081 gtgtggctct cattgatata gggggagggt caacaaccat tgccgtattc cagaacggac 1597141 atctcacttc tacccgtgtc attcctctcg gaggcgaaaa tatcaccaaa gatatctcca 1597201 tcggattgag aacgtcaaca gaagaagcag aacgcgtgaa aaagcaactt ggacatgcct 1597261 actatgacga agcctcggaa gatgaaatat ttgaggtaac cgttataggc accaatcaaa 1597321 aacaaacatt tacacagcaa gaagcagcga atatcattga agcgagagta gaggaaattc 1597381 ttgaaattgt ttcagaagag cttcgcagta tgggaattac cgatctgccg ggaggcttcg 1597441 tgctgacagg aggacaagca gctatgccgg gtgtcatgtc tttggcacag gatgtgctgc 1597501 aaaacaatgt cagagtggca agcccgaatt atatcggtgt aagagatcct caatatatga 1597561 cgggagtggg cctgatccaa ttcgcctgcc ggaatgcaag aatccaaggc agaaaaatag 1597621 gctttaagat gcctgaagaa gcgatacagg aaatcgcagt ctcatcatct gaggaacaag 1597681 agcagcatca tcaccaaaat gaggtgcagc agcggccaaa aggaaaacaa aaaacacaag 1597741 ccgaacataa taaacagagc aaaatgaaaa aactattaag catgttttgg gaatagatag 1597801 atagtcattc ggcagattag gaggatttag catgttggag ttcgaaacaa acatagacgg 1597861 cttagcatca attaaagtaa tcggagtagg aggcggcggt aacaacgccg ttaaccgaat 1597921 gattgaaaat gaagtgcaag gagtagagta tatcgcggta aacacggacg ctcaagctct 1597981 taacctgtca aaagcagaag tgaaaatgca aatcggcgca aagctgacta gaggattggg 1598041 agcaggtgcg aatccggaag tcgggaaaaa agccgctgaa gaaagcaaag agcagattga 1598101 agaagcactt aaaggtgctg acatggtatt cgtgacagct ggtatgggcg gcggaacagg 1598161 aacaggtgcc gcaccggtta tcgcacaaat cgcgaaagac ttaggcgcat taacagtcgg 1598221 cgttgtgaca agaccgttta ccttcgaagg acgcaaaaga cagcttcagg ctgcaggcgg 1598281 aatctcggca atgaaagaag cggtggatac actgatcgtg atcccgaacg accgtatcct 1598341 tgaaattgtt gataaaaaca caccgatgct tgaagcattc cgcgaagcgg ataacgtact 1598401 tcgccaaggg gttcaaggta tttctgactt gattgctaca cctggtctta tcaaccttga 1598461 ctttgctgat gtgaaaacaa tcatgtcaaa caaaggatct gctttgatgg gtatcggtat 1598521 tgctactggg gaaaatcgcg cggcagaggc agcaaaaaaa gcaatttcca gcccgcttct 1598581 tgaagcggcc attgacggtg cgcaaggcgt cctcatgaac atcactggag gaacaaacct 1598641 cagcctatat gaggttcagg aagcagcaga cattgtcgct tcggcgtctg atcaagacgt 1598701 aaacatgatt ttcggttctg ttattaatga aaatctaaaa gatgagattg tggtgacagt 1598761 gattgcaacc ggctttatcg aacaagagaa ggacgtgacg aagcctcagc gtccaagctt 1598821 aaatcaaagc atcaaaacac acaatcaaag tgttccgaag cgtgagccaa aacgtgagga 1598881 acctcagcag cagaacacag taagccgtca tacttcacag ccggctgatg atacgcttga 1598941 catcccgaca ttcttaagaa accgtaataa acgcggctaa tgtaaaggac aaaatcgttt 1599001 tcgattttgt ccttttttgt ttttctcttc acactttcct tcttataaag tctttttccc 1599061 tattgcttcc ttcgcttagt aacaaaacag ataattagac ccatttattt ttgtgacatt 1599121 tttatcattt tcatatatat ggaaattgaa tgacatgaaa cgacaatatc tgtaattcag 1599181 attgtctaca gttaatatac agcgatgttc tgacaaacca ttcattatta aaaggaggga 1599241 cgacactttt tttaaaaagc atgttgaaaa agggggatga aaatgaggaa aaaaacgaaa 1599301 aacagactca tcagctctgt tttaagtaca gttgtcatca gttcactgct gtttccggga 1599361 gcagccgggg caagcagtaa agtcacctca ccttctgtta aaaaggagct tcaatctgcg 1599421 gaatccattc aaaacaagat ttcgagttca ttaaagaaaa gctttaaaaa gaaagaaaaa 1599481 acgacttttc tgattaaatt taaagatctg gctaacccag aaaaagcggc aaaagcggct 1599541 gttaaaaaag cgaaatcgaa gaagctgtct gccgctaaga cggaatatca aaagcgttct 1599601 gctgttgtgt catctttaaa agtcacagcc gatgaatccc agcaagatgt cctaaaatac 1599661 ttgaacaccc agaaagataa aggaaatgca gaccaaattc attcttatta tgtggtgaac 1599721 gggattgctg ttcatgcctc aaaagaggtt atggaaaaag tggtgcagtt tcccgaagtg 1599781 gaaaaggtgc ttcctaatga gaaacggcag ctttttaagt catcctcccc atttaatatg 1599841 aaaaaagcac agaaagctat taaagcaact gacggtgtgg aatggaatgt agaccaaatc 1599901 gatgccccaa aagcttgggc acttggatat gatggaactg gcacggttgt tgcgtccatt 1599961 gataccgggg tggaatggaa tcatccggca ttaaaagaga aatatcgcgg atataatccg 1600021 gaaaatccta atgagcctga aaatgaaatg aactggtatg atgccgtagc aggcgaggca 1600081 agcccttatg atgatttggc tcatggaacc cacgtgacag gcacgatggt gggctctgaa 1600141 cctgatggaa caaatcaaat cggtgtagca cctggcgcaa aatggattgc tgttaaagcg 1600201 ttctctgaag atggcggcac tgatgctgac attttggaag ctggtgaatg ggttttagca 1600261 ccaaaggacg cggaaggaaa tccccacccg gaaatggctc ctgatgttgt caataactca 1600321 tggggagggg gctctggact tgatgaatgg tacagagaca tggtcaatgc ctggcgtgcg 1600381 gccgatattt tccctgagtt ttcagcgggg aatacggatc tctttattcc cggcgggcct 1600441 ggttctatcg caaatccggc aaactatcca gaatcgtttg caactggagc gactgatatc 1600501 aataaaaagc tcgctgactt ttctcttcaa gggccatctc catatgatga aataaagccg 1600561 gaaatatctg caccgggcgt taatattcgt tcatccgttc ccggtcagac atatgaggat 1600621 ggttgggacg gcacatcaat ggcagggccg catgtatccg ctgttgctgc actgctgaaa 1600681 caggcgaatg cctcactttc tgttgatgag atggaggata tattaaccag cacggctgaa 1600741 ccgctcacgg attcaacatt tcctgattca ccgaataacg gatatggcca tggtctggtg 1600801 aatgcttttg atgctgtatc cgctgttaca gatggattag ggaaagcgga aggacaagtt 1600861 tctgtagagg gggatgacca agagcctcct gtctatcagc atgagaaagt aactgaagct 1600921 tatgaaggtg gcagcctacc actgactttg acagctgaag acaatgtgag tgtgacatct 1600981 gtaaagctgt cctacaagct tgatcaaggt gaatggacag aaataacggc taaacgaatc 1601041 agcggtgatc atctaaaagg aacgtatcag gcagagatcc cagatataaa aggaactaaa 1601101 ctaagctata agtggatgat tcacgatttt ggcggtcatg tcgtttcgtc tgacgtatac 1601161 gatgtaacag tgaaaccaag catcacggcg ggatataagc aggactttga aactgcaccc 1601221 ggcggctggg ttgcgagcgg aacaaataat aactgggaat ggggagttcc gtcaactggc 1601281 ccaaatacag cagcatccgg agaaaaagta tatggaacga atttgacagg aaattatgcc 1601341 aactcagcaa acatgaacct tgttatgcct cctattaaag cacctgattc aggaagtctg 1601401 ttccttcaat ttaaaagctg gcacaattta gaggatgatt ttgattacgg ctacgttttt 1601461 gttcttccgg aaggtgaaaa gaattgggag caggctggtg tctataacgg aaagacatca 1601521 agctggacgg acgaagaaat tgatttatcg gcttataaag gccaaaacat tcaagtgatg 1601581 tttaaccttc aatctgatga aagcattgca aaagagggct ggtatattga tgatgtagtg 1601641 ctttctgaca aatcagccgg aaaaacagtc aaaaagaata agctgggcgt cgaaaagccg 1601701 tctggaaagc aaaagaaaaa gccagtaaat ccgaaaaagg ctaagccatc tgcaaacaca 1601761 gcggtaaaac atcagaacaa ggctatacag cctcaagttt tgccgctcaa ggcacaagtc 1601821 agtgtagtgg aaacaggaaa atcaacatat tcagatcaat ccacagggca gtacacgctg 1601881 aagcacaaag cgggagacta tacgcttatg gcagaagcat atggttatca gtcgaaaaca 1601941 caaaaagtat ctttaaagac ggatcagacg acacaagcta attttacgtt agaagagatg 1602001 aagaagggca cattaaaagg cacggtcatc aataaaacga caggagagcc ggtaacaggc 1602061 gcttccgttt atgttgtaga ggatgctgcg gtggaaccgg ctatgacaaa cgacaaaggt 1602121 gaatatatgc tggaggccta tgaaggcgct tatacgatta aagtcgctgc accgggttat 1602181 tacagtgatg aattttccgt tgagttaaaa ggtgatgtta caaaagaaac tgcattgaag 1602241 cctttcgtcg gttatccggg tgaaattgca tatgatgacg gaacagcgga gaatgccaat 1602301 tcctattttg ctgccggtaa cggatgggcg gtaaaaatga cgctcgctga cggcaaggac 1602361 aaaggcatgc ttacaggagg gctgttcaga ttctgggata cagagttccc tgatccgggc 1602421 ggcacagagt ttaaggttga ggtatacgat gccacaggaa aagacggagc accgggcaag 1602481 aaaattgcag ggccatttaa cgcggaagct cttcgcaatg gcgagtggac taaggtagat 1602541 ctcagttcaa aagggattat ggtcgataaa gatttttatc tcgtatatat ccagtcgaaa 1602601 cctgatccgt attcacctgg attggcaatg gatgaaaccg gccagaattc cggccgcaac 1602661 tggcagtata tagatggaaa gtggcagcca ggtgacaaag cggatggcaa ctatatgatt 1602721 cgcgcattag ttgattatga agctgctgta cctgagatta cttcaccgac agacaaatca 1602781 tacacaaata aggatagcgt cactgtaaaa ggaaacgctt ctcctggcac aacggtacac 1602841 atttataatg gagagaaaga agcaggagaa acgaaagctg ctgcggatgg cacgttccat 1602901 gcaggcatca tactcaacaa gggtgaaaat gagctgacgg caactgcatc aactgacaac 1602961 ggaacaacag atgcctccag cccaatcacg gtcacgcttg atcaagaaaa gcctgaatta 1603021 acactggaca atccaaagga tggcgggaaa acaaataaag aaacgctgac tgtcaaaggg 1603081 gctgtatccg atgacaatct gaaagacgtc aaggtgaatg gcaaaaaagc aacagtagct 1603141 gatggttcat actcagcccg tattcttttg gaaaatggaa gaaatgaaat caaggtaatt 1603201 gctacagact tggcaggcaa caaaacgacg aaaaagacag tcattgatgt gaactttgac 1603261 aagcctgtca tttccggctt aattccggga gaggataaaa acttaaaagc cggtgaatct 1603321 gtgaaaatcg ctttctcaag cgctgaggat ttagatgcaa cgtttaccat tcgtatgccg 1603381 ctgaccaatg caagagcgag tgtgcaaaat gccaccgaac tcccgttaag agaaatctct 1603441 ccggggagat atgaaggcta ttggactgcc acttcttcta ttaaagcaaa aggagcaaaa 1603501 gtagaagtga tcgtccgaga tgattatgga aatgaaacaa gaaaaactgc gaatggaaaa 1603561 cttaatatga acacagaaaa ttaagtggaa aaaaagctgc cgtcattggc agcttttttt 1603621 atatcctctc attatacttc ctcgacaaat taagcagatt tccctgaaaa attgtatttt 1603681 cctctcaaca ttaattgaca gactttccca cagagcttgc tttatactta tgaagcaaga 1603741 aggggaacag cgtgaggcaa gaaagaaagg agtcagatgt gaaaatctat ttagatgtca 1603801 tttggctgtt aaacttttgt tttgatgcac ttttgctttt gctcacggca tttattttaa 1603861 aacggcatgt aaaaaaaaga agactggtag gcggagcgtt catcggttcc agtattgtcc 1603921 ttttgatgtt tactcctttt tcgccgattg ttgaacatcc ggctgggaag ctagcttttt 1603981 cagttgtgat tgtggtggtg acatttggct ttaaaagatt tcggtttttc tttcaaaatt 1604041 tgttttcctt ttattttgcc acttttttaa tggggggagg aattatcgga gcccattctt 1604101 tgctgcagtc aaattctatt gttcaaaacg gtgtcatgat taccaatcaa acagggtttg 1604161 gagacccgat cagctggttg tttattgttg gtggctttcc agcattatgg tttttttcta 1604221 aaagaagaat tgaagatatt gaaacaaaaa acattcaata tgaggaacga gtcagcgtgc 1604281 aggcagattt gggcagccaa acacttcatg tcagaggcct gattgattcc ggtaaccagc 1604341 tgtacgatcc tcttacaaaa acaccggtaa tgatcattta cattgataaa ctggagccga 1604401 ttttcggaac agccgaaacg atgatcattc gaaacacaga cccattggaa gccatcgaac 1604461 agctcgatga ttcctttcgc tttttagata aaatgaggtt gattccatac aggggagttg 1604521 gtcagcaaaa tcaattttta ttatgcgtta aaccggatca cgtaacgatt atgacaaaag 1604581 aagaaatgat ttctgcagat aaatgtttaa tcggtatcag cacaacaaag ctgtcggcag 1604641 atggagagtt tgacgcgatt attcatccga aaatgctttc gggcaaggct gtcaaacacg 1604701 tttcataatg ttcgcaaatg tccgttactt atcatactca aacggcgtga catttagaag 1604761 ggagaggaag atgaaaaaac tgaaattacg gttgacgcac ctctggtata agctgctgat 1604821 gaaacttggg ctgaaaagtg atgaagtcta ttacataggc gggagtgaag ccctgccgcc 1604881 tccattatct aaagatgagg agcaggtttt gttaatgaag ctcccaaacg gcgatcaggc 1604941 ggcgcgcgcc attctaattg aacgcaattt gcgtctggtc gtatatatcg cccgtaaatt 1605001 tgaaaatacg ggaattaata tagaggattt aatcagcatc ggtaccatcg gtctaatcaa 1605061 agctgttaat acatttaatc cagaaaagaa aatcaagctt gctacctatg cctcccggtg 1605121 tatagaaaat gaaatcctga tgtatttaag aagaaataac aaaatccgtt cagaggtttc 1605181 ctttgatgaa ccgcttaata ttgattggga cggcaatgag cttttgcttt ctgatgtgct 1605241 cggcactgac gatgacatca tcactaaaga catagaagct aacgtcgata aaaagctttt 1605301 gaaaaaagcg cttgaacagc ttaatgagag agaaaagcaa atcatggagc tgcggtttgg 1605361 gcttgtcggt gaagaagaaa aaacccaaaa ggatgtagcg gatatgatgg ggatttctca 1605421 gtcttatatt tcgcggcttg agaaaagaat tataaaaagg ttgagaaaag agttcaacaa 1605481 aatggtgtaa aaaattttat ggttagaacc ccttgatttt acagggattt cctgatttcg 1605541 acagtttttc ggtctgagtg cagtgcatat ttttcccacc caaggagata cttaacgttg 1605601 tacagcagct cctgtaggga gggaaaaaag tgtcgagaaa taaagtcgaa atctgcgggg 1605661 tggatacctc caaattacca gtactcaaga atgaagagat gagaaagctg tttaggcagc 1605721 tgcaggatga aggcgatgat tcagcaagag aaaagcttgt aaacgggaac ttgcgtcttg 1605781 tcttaagtgt cattcaacga tttaataaca gaggggagta tgttgatgac ttatttcaag 1605841 tcggctgcat cggactaatg aaatccattg ataattttga cctaagccac aatgttaagt 1605901 tttcaacata cgctgtacct atgattatcg gagagatccg caggtattta cgtgataata 1605961 acccgatccg tgtctcaaga tcactccggg acatcgctta caaggcgctt caggtaagag 1606021 agcggttaat cagtgagaca agcaaggagc cgactgcaga agacatcgca aaagttcttg 1606081 aagtaccgca tgaggaaatt gtatttgcgc ttgatgccat tcaggatccg gtttctctat 1606141 ttgaaccgat ctataacgac ggcggagacc cgatctatgt gatggaccaa atcagtgatg 1606201 agcgtaatac agattcacaa tggattgaag agctggcttt aaaagagggc atgagaaggc 1606261 tgaacgatag ggaaaaaatg attttgagaa agcgattctt ccaagggaaa acccaaatgg 1606321 aagtcgccga ggaaatcgga atttctcaag cgcaggtgtc cagacttgaa aaagcggcta 1606381 tcaaacaaat gaataaaaat attcatcaat aatgaaaagc ctttaaaacg atgttgtttt 1606441 aaaggctttt ctattgatta tggatggttt acgttttgga aaaagtaagg tatcctagtt 1606501 cgtacaaagt tttatgaaaa ttaaaacaat tataaaaggc aataaagagg aggaccacga 1606561 tgattttgca gcttgacaat gtctcactaa aacggaatgg gaaatggata ctgaaagata 1606621 ttcattggaa ggtggaagaa aaggaaaatt gggtgcttta cggcctaaat ggcgccggga 1606681 agacagcgct gttaaatatg ctttgctcat attattttcc aacatcaggc gagatgcagg 1606741 tgctcggcca tgaatttggc aaaacagagc ttggggaaaa gctcagacgt aaaattggcc 1606801 tcgtctcagc agctcttcag caaaaattgt atccggcaga ttcagctttt gaaattgctt 1606861 tgagcggagc ttacgcttcg attgggttat atgaaacgcc aagtaaggaa accagggaaa 1606921 aagcgatagg tttgttagag gacttgggag caattgaata tgccgatcgc cgctatgaaa 1606981 ccctttctca aggggaaaaa caaagagcat tgattgctag agcactaatg gccgatccgg 1607041 agctgctgat actggatgaa ccagtcacag gactggattt tattgcccgg gaaaagctgt 1607101 tagatacgat tacatacatt gcaaacaaag aaaatgcacc atctatcctt tatgtgactc 1607161 atcatgctga agaaattttg cctgtctttg ataaagccct tttattaaaa cagggagagg 1607221 tttttggatc cggagaaata aaggaaatgc ttactgatca aatactttcc gctttttttg 1607281 atacgccaat ccatgtatta tggaatcagg atcggccgtt tttaacaaga gctgagccga 1607341 taacgaatgc ctgacaaata tatatagatt catcctaggg gtgctttgcg aagctgagag 1607401 agactttgtc tcaacccttt tgacctgatc tggatcatgc cagcggaggg aagcggtgaa 1607461 aagcggagta catcggactc cgtttgtttt tattaagccg tttcatcaca tttgaaacgg 1607521 cttttttgat tttaaagaat aggagcggat ttacattgga tcaacaaata tactctttgc 1607581 aaaaaaaagt ggaagaacat aaggaggagc ttattcagct tgcgaaaacg ctgatttctt 1607641 atcaaacacc tgctccgcct gcaagaaata cagagggcat tcagtcttgg attgcgggat 1607701 atttaaatga attgggattc tcgatcgaca aatgggatgt gtaccctgga gatcccaatg 1607761 ttgtagggaa gctaaaagga acagattcag cagattatta tagcctgatt atcaatggcc 1607821 atgtagatgt ggcagaggta aaagaggatg aagaatggaa gcacgatccg tttcatccca 1607881 ttgaaaaaaa cggtctctta atcgggcgag gcgcttccga tatgaagggc ggaatggctt 1607941 gtgtgctgtt tgctgtcaaa ttaattcgtg aagcaagcat tgaacttcca ggtgatctga 1608001 ttctgcaatc ggttattggg gaggaagttg gagaggccgg cacacttgaa tgctgcaaga 1608061 ggggctacca cgctgatttt gcaattgtcg cggatacgag cgatatgcat attcaaggcc 1608121 aaggcggtgt cattacaggc tggatcgaaa tcaaaagcag tcaaacattt catgatggaa 1608181 cgagacggaa tatgattcat gcaggcggag gaacattcgg agcaagcgca attgaaaaaa 1608241 tggcaaaaat cattgcgggg ctcggtgaac ttgagcgcca ctggtctatt atgaaaagtt 1608301 atcccggttt taaaccaggc acaaatacga ttaacccggc agttatagaa ggcggcagac 1608361 atgcggcttt tatagcggac gaatgccggc tgtggatcac agtccatttt tatccgaatg 1608421 aaacccatga ccaagtggca gcggaaatag aagattacgt caatcggctg agtgacagtg 1608481 atatttggct tagggaaaac cgccctgtat tcaagtgggg aggctcatct atgatagaag 1608541 acaggggaga aatttttccg gcattggaag ttgaccctgg ccacccaggc gtcttagcgc 1608601 taactgcctc tcatcagaaa gtgaaacggg agtgtccaat tattgacgtt tctcaatcag 1608661 ttacagatgg cggatggctg tatgatgccg gtattccatg cgtaatatac ggtcctggag 1608721 atctgcacaa tgcacactct gtgaacgaga aggtatcgat tgagcagcta gtagagtata 1608781 caaaaattat actcgatttt atcatcagct ggtgcagccg gaaaaaagaa caatgacatg 1608841 aaaatttctt cttgctgaca aggttcagcc tgcccgttca tatacttgaa caaaaggacg 1608901 gaaaaaggac gtgatggaat gatcagcatt tcagaatttc aggtaaagga tgtcgtcaat 1608961 gtctcaaacg gaaaaaagct ggggagtatt ggtgatattg atatcaatgt gaccactgga 1609021 aaaattcagg cgatcatact cggaggaaat gggaaagttc tcggattttt tggaaaagaa 1609081 gaggaattgg tcattccatg gcgaaatata gtaaaaatcg gggaagatgt aatcttagtc 1609141 cgattaagtg aaccacatgc ataaacctgc ttgtctgccg cagattggca aatgccggaa 1609201 gtctcgattc ttccggcaca tttcatttag aaatatgcaa atcggcgctc aacgaatgca 1609261 gtaagatgtg gtaaaataag tgggaaattc cgctttttta aatgtttgtc gaaaggttgg 1609321 atcatcatga atacatatca cccattcagt cttaccacac cctcgacact catgatacaa 1609381 gactgggctc aaacgaatca aaacaacaaa gaggtcattg ccggatttac gacaaaaaac 1609441 ggcggtgtca gccaaaagcc ttttgaatcg ttaaatacag gattgcacgt tcatgacaaa 1609501 gatgcagatg tagttaaaaa tcgtgaatat attgccgata tgtttaatac tgatttgcag 1609561 tcttgggtat tcgctgatca gacacatgat aatcgcgttc agaaagtgac gcagagggat 1609621 aggggaaaag gcgcccgtga gtatcacacg gctctaaaag caacggacgg gatctataca 1609681 aatgaaaaaa atgtattttt agcattatgc tttgctgatt gtgtgcctct tttcttttat 1609741 gatccggtta agtcgcttgt cggagtcgcc catgccgggt ggaaaggcac cgtcaaacag 1609801 attggcagag aaatggtgaa gcaatggact gagaaggaag gttcaaatcc ctcagatatt 1609861 tacgctgtta ttggcccgtc tatcagcgga gcatgctata cggtagacga ccgcgtcatg 1609921 gatgctgtcc gcgcattgcc ggtttcagca gaccttgccg ccaatcagac ggcaaaggca 1609981 caatatcagc ttgatctgaa agagctgaac cgtcttatac tgatggacag cggtttggca 1610041 agtgaacaaa tttctgtcag cggtttatgc acggaaagcg agccgtctct tttctattct 1610101 catcgccgcg atcaggggaa aactggacgg atgatgtcct ttatcggaat gaaggaggca 1610161 taaaagatct tgcgtgttgt tgataattta cgacatataa acgaacgaat aaacgaagca 1610221 tgtaacagat cgggccgcag ctccgatgaa gttacggtta ttgcagtcac aaaatatgta 1610281 tcacctgaaa gagcacagga ggcagtagat gctggcatca cctgcctcgg agagaatcgg 1610341 gatgcggaac tgctccgcaa acaggaattg atgaaaggga atccggaatg gcattttatc 1610401 ggcagtctgc aatcaagaaa agcaaaatct gtcgtcaatt cggtttccta tatccattcc 1610461 ctagaccggc tctcattagc gaaagaaatt gaaaaacggg ctgaaggtac tgtacgatgc 1610521 tttgtgcagg tcaatacctc tcttgagcct tctaaacatg gcatgaaaaa agaagaagtc 1610581 attccattca tacaggagct ttccggtttc gaacatatcc ttgttgccgg gctgatgaca 1610641 atggctccgc tgactgatga tcaagatcag atcagaagct gtttcaggtc gctgagagaa 1610701 ctccgtgacc aggttcagaa gctgaaccag ccgaacgctc cgtgtactga actgtcgatg 1610761 ggcatgtcaa atgattttga aattgcaatt gaagaaggag ctacttatat tagaatcggc 1610821 tcatcgttag tcggaaatga aacagggggt gtacagcaat gagtatgaaa aataaactga 1610881 aaaacttttt ctcaatggaa gatgaagaat acgaatatga atatattgag acagagcggg 1610941 aatctcatga ggagcatgag caaaaagaaa agccggctta caacgggaat aaacctgcgg 1611001 gcaaacagaa tgtagtgagc ttgcaaagtg ttcagaaatc ctctaaagtg gtgttgagtg 1611061 agccgcgcgt ttatgcggag gcgcaggaaa tagccgacca tttgaagaac cggcgggcag 1611121 ttgtcgtcaa tcttcagcgg atacagcatg accaggcgaa gcggattgtt gactttttaa 1611181 gcggaaccgt ttatgccatt ggcggcgata ttcaaagaat cggctcagat attttcctct 1611241 gcacgcctga caacgtagat gtatcaggca caatttctga gctcatatct gaagacgaac 1611301 atcagaggtg gtaaagcgag atgatccttt atcaagtttt ttcggtttta agcttattaa 1611361 tcacaatata ctcatttgcc ctgatcatat atatttttat gtcatgggtg ccgagtacga 1611421 gggaaacagc agtcgggcgt tttttggctt cgatttgtga accatatctc gaaccattca 1611481 gaaaaatcat ccctccgatt gcaatgctgg atatttcacc aatcgtagca atacttgtgc 1611541 ttcggtttgc gacaaccggc ttgtggggac tttatcgcat gattgcgttt taatgtgaca 1611601 gtttgatagg ggcttggcag cagccaagcc tctttacata gaagggaaag acgatgagcg 1611661 atatatatca gcacttcaga aaagacgagc gggcctttat tgatcaagcg ctcgaatgga 1611721 aaagaattgt ccaggagcag taccggatga agctgaccga ctttttagat ccccgagagc 1611781 aggtcatcct ctctgctgtt acgggacagg cagatgtcgg gcttgccttt tccggcggct 1611841 atgacagagc ggagcggaaa cgggcgattc tgtttccaga gtacattact ccggaagaat 1611901 cagattttga actgcaggcg tttaacgtcc gttatgctga caagtttgtc tcagtagatc 1611961 atcgttctct gcttggtgca ttaatgggca taggattaaa gcggcaaaaa ttcggtgaca 1612021 tcgtgttttc tgagacagca gtgcaattga ttgtctcagc cgataccgct gattttgtgg 1612081 ctgcacagct gacccaagca ggcaaagcgg cggtcagcct agagaaaatc gacttgtcag 1612141 accttaacat tccagcagtt gatgtcgaaa taagagatga cacggtttct tctttaaggc 1612201 ttgacgccgt ctgcgcctct atgagcaggc aatcccgcca gaaatcacag acgcttgtga 1612261 aaaacggcct tgtgaaagtg aactggaagg tggttgaaga tccttcatac atagtcgcgg 1612321 aaggggacat gctgtctatc agaggttttg gccggtgcag cttaacaaaa atcgaaggaa 1612381 aaaccaaaaa agacaaatgg agagttacgt ttgaacgaca aaaatagtcg gtttttcagt 1612441 ttttttctcc atctgtgcga aatttgtttt ataatgtgaa ctagataacc gtactgaaat 1612501 gtaaaaatgg aggtggcatc atgccattaa cgccaaatga tattcacaac aagacgttta 1612561 caaaaagttt tcgcggatat gatgaagatg aagtaaatga attcctagcc caagtcagaa 1612621 aagattacga aattgttctc cgcaagaaaa ctgagcttga agcgaaagtc aatgagcttg 1612681 atgaaagaat cggacacttt gccaatattg aggagacatt gaataaatca attttagttg 1612741 ctcaagaagc ggctgaagac gtaaaacgca attctcaaaa agaagcaaag ctgatcgttc 1612801 gggaagcgga gaaaaacgct gatcgcatta tcaacgaatc gttatcaaaa tcaagaaaaa 1612861 ttgcaatgga aattgaagag ctgaaaaaac agtctaaagt gttcagaaca cgtttccaaa 1612921 tgctgattga agctcagctt gatcttctga aaaatgacga ttgggatcat ctccttgagt 1612981 atgaagtcga cgctgtattt gaggaaaagg aataaattct ctgattatct tgacattttc 1613041 ttagcttgtc gaatataata cgttcataaa ttcagatgaa aaaacggttg aaagggacag 1613101 tcatgtttcc ttcaggcctt catagcgacc cggagatggt gagagtccgg gatggccgga 1613161 atcatgtaga tcagcccttt agtttccttg ctgaactcac agtaggttag gacgttcatc 1613221 acgttacgat gctcaagagg aaaaagtgta tgcttgcttt ttctaaaagg gtggtaccgc 1613281 gagataagct ttctcgtccc ttatgggatg agagggcttt ttttattttc tgaaaaaatg 1613341 cagtggagga atgaaaatgg attttaaaga cacgctctta atgccgaaaa cagatttccc 1613401 gatgcgtgga aatttgccaa accgtgagcc tgacattcaa aaaaaatggg aggaagaaga 1613461 tatctaccgt cttgttcagg aacggacgaa agaccgcccg aaatttgttt tacatgacgg 1613521 acctccgtat gcaaacggcg acatccatat gggccatgca cttaacaaga ttttgaaaga 1613581 cttcattgtc cgctataaat caatgagcgg ctacaacgca ccgtatgtgc cgggctggga 1613641 tacacacgga ttgccaattg aaacagctct gacaaaaaac aaaaaggtca accgcaaaga 1613701 aatgtcagta gcggaattcc gcaaactatg cgaagagtac gcttggaagc aaatcgaggg 1613761 acagcgtgag caattcaaac gtcttggtgt ccgcggtgac tgggaaaacc catatgtgac 1613821 attaaaaccg gaatacgaag cgcagcaaat ccgcgtattt ggtgaaatgg caaaacgagg 1613881 ctacatttac aaaggcctta aaccggttaa ctggtcacct tcaagtgagt ctgctctggc 1613941 tgaagccgag atcgaatatc aagataaacg ttcagcatct atttacgtcg cttttggtgt 1614001 aaaagacgga aaaggcgttc ttgaaaacgg cgagcgcatc atcatttgga caacaacgcc 1614061 gtggacaatt ccggcgaacc tcggaatctc agtgcaccct gatcttgagt acagcgtgat 1614121 tgcagtaggt gaagaccgct ttgttgtagc aagtgcctta gtcgaaaatg ttgcatcggc 1614181 atgcggattt gatcagtatg aagtgacaag aacggtcaaa gggaaagacc ttgagaacat 1614241 tatcgctgaa cacccgctat atggcagaga ctctctcgtt atgcttggtg aacacgtaac 1614301 aactgatgcc ggaacaggct gtgttcatac agcgcctgga catggggaag atgactttat 1614361 catcggccaa aaatacggtt tagatgtgct ttgcccggtc gatgaaaaag gtgtaatgac 1614421 aagcgaagct cctggctttg aaggcatgtt ctatgatgat gcaaacaaag cgatcacaca 1614481 gcagcttgat gaaaaaggcg cacttgtgaa gcttgaattc attactcatt cttatccgca 1614541 tgattggaga acaaaaaaac caaccatttt cagagcaaca gcgcaatggt ttgcgtctat 1614601 taaagatttc agatcagacc tgctggatgc cattaaagaa accaaatggg ttcctgaatg 1614661 gggcgagcag cgtttgcaca acatggttcg ggaccgcgga gactggtgta tttccagaca 1614721 gcgtgcgtgg ggtgtgccga ttccggtatt ttacgctgaa aacggagaac cggttattac 1614781 agatgaaacc attgaacatg tttctgaatt gttcagacag catggatcaa acatttggtt 1614841 tgaaaaagaa gcaaaggatc ttcttccgga aggctttacg catcctggca gcccgaacgg 1614901 cacatttaca aaagaacagg atatcatgga tgtttggttt gattcaggct cttcacatca 1614961 agcagtgctt gaagaacgtg atgacctcgt tcgcccggct gatctatacc tagagggatc 1615021 tgaccaatat cgcggctggt ttaactcttc tctttctaca gcagtagccg taacagggaa 1615081 agcgccgtat aaaggtgtgc tcagccatgg gttcgcactg gatggagaag gacgtaagat 1615141 gagtaaatca atcggtaacg ttgttgttcc ggctaaagtc atgaaacagc ttggtgccga 1615201 catcttaaga ttatgggtat cttcagtgga ttatcaggcg gacgttcgcg tgtctgacgc 1615261 cattctgaag caggttgcgg aagtatatcg taaaatccgc aacacgttcc gtttccttca 1615321 cggcaacctt ttcgattttg atccaaaaac aaatgcggtg gctgtcgaag atcttcgcga 1615381 agtggatcag tatatgctga ttaagctgaa caagctgatt gataaagtga aaaaagcgta 1615441 tgatgagtac gaatttgcgg ttgtgtatca cagcattcat aatttctgca caatcgaatt 1615501 gagctcattc taccttgatt ttgcaaaaga tattgtctac atcgagcatg cggatcatcc 1615561 ggatagacgc agcatgcaga cagtattcta cgaaacgctt cttgcattag tgaagctttc 1615621 agcgcctatc cttccacata cggcagacga attgtggtct catttaacat ttgttgaaga 1615681 gcagagcgtt cagttgaccg atatgccgga aacaatcacg gttccaaaca gtgaagcgac 1615741 tgaagaaaaa tttgaccgct ttatggctct tcgtgatgac gtgttaaaag cattagaaac 1615801 tgcgcgaaat gaaaaaatta tcggtaaatc tttggaagca aacctgaaat tgtatccaaa 1615861 caaagaaaac aaggagctct tggcttccat aaaagaaaac ctttctcagc tgtttattgt 1615921 gtctgaactg acaatcagcg aagaaaatga agcgccgaac gatgcgcaaa gctttgcgac 1615981 gggtaaaatc gctgtcgaga aagcggaagg cgaaatgtgt gagagatctc gtgtgatttc 1616041 aaaagatgta ggggcaaatc cgaaatatcc tacactttca ttacgcaacg ctgaaatcgt 1616101 tgaaaaatac tatcaaaaat aatgcaaaag agcccggcgt aaaagccggg ctttttttgt 1616161 gccaagagtg acatccttta gaacgaaagg aaaaatctta tgggctttag atcatcattc 1616221 acaggcaaca ataaagatac tacgttaaga gcaggagttg tgaagaatga atgatcaact 1616281 gaccgcaatt tatacggaac ttcttctgat gaaagaagaa ttacagtcga gattatttga 1616341 gtattcttgc tttcaggttt ctacaagccc gcaagcagca atcaatcaaa aacaaaaagc 1616401 aactctgatc tatcatatta aagaagaact tcaagacgtt ctccttgcat tgtccaaaat 1616461 cgaaaacggc acattcggat actgtgaaga aactggggcc cccattcctc ttgcaaagct 1616521 ggcagtgctg ccgacggccc gaacagcaaa cgattttctt tattctgtcc aatttgagaa 1616581 aaaaacgctt ccgatatgga aatcaacgga tatcgaatat ggtcaggcac tgtatgaata 1616641 acagtgtctg tccggttaat atgcctgata tttctttact ccagtgcttt ttattgataa 1616701 aatgcataat ggattaaagt aaccgtaaac tggaggaacg tttgtgctgt attatatgat 1616761 tgcactactt attattgcag ccgatcaatt gacaaaatgg ctagttgtta agaacatgga 1616821 acttggccaa agcattccga tcattgatca ggtattctat atcacctccc atcgcaatac 1616881 gggtgctgca tgggggatat tagcgggtca aatgtggttt ttctacctca taacaaccgc 1616941 tgttattatt ggtattgttt attacataca gcgttataca aagggacaaa ggcttcttgg 1617001 cgttgccctc ggacttatgc ttggcggtgc catcggcaac tttatcgatc gggctgtcag 1617061 acaggaagtt gtggatttta tccatgttat tattgtcaat tacaattacc cgatatttaa 1617121 catcgcggac tcttcactat gtgtcggcgt aatgctttta tttatacaaa tgctgttgga 1617181 cagcgggaaa aagaaaaagg agcaatagca tgaatcaaat tgatataacc gcttcagaag 1617241 aacaaaaaag tgagcggatt gataaatttt tggcatcgac tgagaatgat tggtcaagaa 1617301 cccaggttca gcaatgggta aaagacggac aggttgtcgt gaacggaagc gcggtgaaag 1617361 cgaattataa aattcagccg ggtgatcagg tgaccgtcac tgtacctgaa ccggaagcgc 1617421 tcgacgtcct ggcagagcct atggatctgg atatttatta tgaggaccag gatgtgctgg 1617481 tcgtcaacaa acctcgcgga atggttgttc acccagcacc cgggcatctt acgggcacac 1617541 ttgtaaacgg tcttatggct cattgcacag acctttccgg aataaatggt gtgatgcgcc 1617601 cgggtattgt tcacagaatc gataaggaca cgtccggttt attaatggtg gcgaaaaatg 1617661 atatggcgca cgagtcactc gtaaaccaat tggtcaacaa aacggtcacg cggaaatata 1617721 cggcggttgt ccacgggctt atttctcatg atgacggcac aattgacgcg ccgatcggac 1617781 gggataaaaa agaccgtcaa agcatgactg tgacacgtga tggcaaaaac gctgtcactc 1617841 attttcatgt gcttgagcgt tttcaggatt ttacgttagt ggagtgccag cttgaaacag 1617901 ggagaaccca tcaaattcgt gttcatatga aatatatcgg attcccatta gcaggcgatc 1617961 cgaaatacgg cccaagaaaa acaatcgact ttaatggcca agcgcttcac gcgggagttt 1618021 taggttttga ccatccacga acaggagaat atgtcgaatt tgaagcgccg cttcccgagg 1618081 atatggcaga attaatcgaa aacctcagaa aaaacggttg acagagggtt tcttttctga 1618141 aataataaac gaagctgaat agattcttta aaacagtcca gagaggctga gaaggataac 1618201 ggatagacgg gatgcgtgta taggcgcgca ccttgtccta aaacccctct atgctctggc 1618261 aggaggggtt ttttcttcta tatgaactgt gaggtgtcac acattgaatc aaaaagctgt 1618321 cattctcgac gaacaggcaa ttagacgggc gctgaccagg attgctcacg aaatgatcga 1618381 acgcaataaa ggaatgaata actgcattct tgtcggcatt aagacaagag ggatttacct 1618441 ggcaaaacgc cttgcggaac gcattgaaca gattgaggga aatcctgtta cagtcggtga 1618501 aattgatatt actctttaca gagatgatct ttctaaaaaa acaagcaacg atgaaccgct 1618561 tgtaaaaggt gcagatattc cggtagatat tacagatcaa aaagtcattc tcgttgatga 1618621 tgttctgtat accggaagaa cagtcagagc aggaatggat gcgcttgttg atgtaggcag 1618681 accttcctcc attcagcttg cagtgcttgt ggacagagga caccgggagc tgccgatccg 1618741 agcggattat atcgggaaaa acatcccgac atcaaagtct gaaaaggtta tggtacagct 1618801 tgatgaggta gaccaaaacg atctcgtcgc catttatgaa aacgaataat agatcacctt 1618861 tttaagggca atccagagag gttgcaaaga ggtgcacaac aaaggcccaa aaagtattcg 1618921 gcaggtcttt gtatgcctct ttgcgtaaaa aagcaaagag gtttttttat acagtcattg 1618981 agtcatccta aaatgaaagt caacaatcag ggggaaatca tcatgagtaa gaaaaaagta 1619041 aatttagggg tcagggatgt cccgacacct ttctcttggg tttcattcag ccttcagcat 1619101 ttgtttgcca tgtttggctc aaccattttg gttccgaagc tcgtcggaat gagtcctgct 1619161 gtggcgttgg tgacaagcgg catcggaaca ctggcgtacc ttcttattac caaaggacaa 1619221 attccggcgt atctcggttc atccttcgcc tttatttctc cgatcattct ggtaaaagcg 1619281 accggcgggc cgggagcggc aatggttgga gcgtttcttg cagggctggt gtacgggctg 1619341 attgccttat tgattaggca gcttggaaca ggatggctga tgaagattct cccgcctgta 1619401 gtcgtagggc ctgttattat cgtcatcggg ctgggactgg caagcactgc agtaaacatg 1619461 gcgatgtatg ctgatccgaa cgcgagtgag ttggtctaca gcttaaagca ctttagtgtc 1619521 gcaggagtta cgctggcaat tacgattatt tgtgcgattt tcttacgagg gtttttaagc 1619581 ctgattccgg ttctgatcgg aatcatcggc ggatacctgt ttgcccttac tcaagggatt 1619641 gtcaacttcc agccggtgct tgacgcgaaa tggtttgcag tgcctgaatt tatcattccg 1619701 ttcaaagatt attcaccgtc agttacgctc ggcatcgcag ccgcaatggt tcctgtcgca 1619761 tttgtcacaa tgtcagagca tatcggccac caaatggtgc tgagcaaggt tgtcggacaa 1619821 gacttcatta aaaagccagg tcttcatcgc tctattatgg gtgacagtgt ggcgacaatc 1619881 ctcgcttccc tgatcggcgg ccctccgaca acgacttacg gagaaaacat tggcgtgctg 1619941 gccatcacaa gagtattcag cgtctttgtc atcgggggcg cggcagtgat tgccctttgc 1620001 ttcggcttta tcggcaaaat ttcagcgctg atcagttcag tgccgtcagc ggtcatggga 1620061 ggcgtctcct tcctgctgtt cggaatcatt gcttcaagcg gcctgagaat gctgattgac 1620121 aacaaaattg attatgaaaa caacagaaac ctcattatta catcagttat ccttgtcatc 1620181 ggtgtaggag gcgcttttat ccaagtgtct cagggcggat tccaagtgtc aggaatggcg 1620241 cttgccgcaa ttgtcggtgt catcttaaac ctgattcttc cgcaggcgaa ggaagagcag 1620301 gcagacacat ctgaacaaca tcatatttaa aaccttttaa tgaaagtcca gagaggcttg 1620361 gaagggttat gaagagaagg aagcttcaat gctgccctct atttaaccat accccgagtc 1620421 tatcttagac cggggttttt tttcagcctt aagttgaaaa gagaggggaa agaacatgaa 1620481 gcatttaacg acgatgagtg aacttagcac tgaggaaatc aaagatttgc ttcaaacagc 1620541 acaagagctc aaaagcggaa aaacagacaa tcagcttaca ggaaagtttg cagcaaacct 1620601 gtttttcgaa ccgagcacga gaacgcggtt cagctttgag gtcgcagaaa aaaagctggg 1620661 catgaatgtg cttaaccttg atggaacaag cacaagcgtg caaaaaggcg aaaccttata 1620721 tgacacgatc cggacgcttg aatcaatcgg tgtggacgtc tgcgtcatca ggcacagtga 1620781 ggatgagtat tatgaagagc ttgtcagcca ggtgaacatt ccgattctga atgcgggaga 1620841 cgggtgcggc cagcatccaa cacaatcact gcttgattta atgacgattt atgaagagtt 1620901 caatacgttt aaagggctta ccgtctccat tcacggcgac atcaagcata gcagagtggc 1620961 aaggtcaaat gcggaagtgt tgacaagatt gggtgcccgg gtcctatttt ccggcccttc 1621021 ggaatggcag gatgaagaaa atacattcgg cacgtatgtc tcaatggatg aagcagttga 1621081 gtcttccgat gttgtcatgc tgctgcgcat tcaaaatgaa cgacatcagt ccgctgtcag 1621141 tcaggaaggc tatttaaaca aatacggctt gaccgtagaa cgggctgagc gtatgaagcg 1621201 gcatgcgatc atcatgcatc ctgctccggt aaacagagga gtggagattg atgacagctt 1621261 agtagaaagc gaaaaatcaa gaatcttcaa gcaaatgaaa aatggcgtat ttatcagaat 1621321 ggcagtgata cagcgtgcct tacaaaccaa tgtgaaaaga ggagaagcag cgtatgtcat 1621381 atctcattaa aaacggctgg atactaaacg aaaatggtga aaaaacacaa gcggatatcc 1621441 gagtgactgg agaaaccatc accgcaatcg gcaagcttga tgcaacggat aatgaaacgg 1621501 taattgatgc aaaaggtttg ctcgtttcac ctgggtttgt tgatctccac gtgcatttca 1621561 gagagccggg cggagagaaa aaagaaacta ttgaaaccgg ggcaaaagca gcggcgcgcg 1621621 gcggctatac tacagtagca gcaatgccga atacgcggcc ggttcctgat acaaaggagc 1621681 agatggaatg ggtgcaaaac agaattaaag aaacatcatg cgtaagagtt cttccatatg 1621741 catccattac gatcagacaa atcggcgatg aaatgacaaa ctttgaagcg ttaaaagaag 1621801 ccggggcatt tgcttttaca gatgacggcg ttggtataca gacagcagga atgatgtatg 1621861 aagcgatgaa acgggcagcc gcaattgaca aagcgattgt tgcacattgc gaggacaact 1621921 ccttaattta cggagggagc gtacatgagg ggacattctc caaagcgaac gggctaaacg 1621981 gcattccttc tgtgtgtgaa tcggttcata ttgctcgcga tgtgctgctg gctgaggcgg 1622041 caaactgcca ttatcatgta tgccatatca gcacaaaaga atctgtcaga gttgtacgcg 1622101 atgcgaaaaa agcgggaatc agagtgacag cagaagtatc gccgcatcat ttgctgcttt 1622161 gtgatgagga catcccgggg ctggacacaa actataaaat gaatcctccg ctccgcagcc 1622221 cagaagacag agctgcttta attgaaggtc ttttagacgg aacaattgat tttatcgcaa 1622281 cagaccatgc accgcatacg gaagaagaga agaacacaga aatgaagctg gcgccattcg 1622341 gaattgtcgg cttagaaaca gcattcccgc ttctttacac acactttgtc aaaaatggca 1622401 gctggtcact gaagcagctg attgactaca tgacaatcaa gccatgcgaa gcgttcggtc 1622461 tcccatatgg aacattacaa acggggcaag ctgcggacat tacgttaatc gatttagaaa 1622521 aagaagcagt tatagacaaa gagacatttt tatcaaaagg aaaaaataca ccattcaacg 1622581 gcatcagttg caccggctgg ccggtcgcta caattgcggc agggaagctt gcttatgaag 1622641 aggggagact tgtcaaatga agagacgatt agtactggaa aacggagcgg tattcgaggg 1622701 agaagctttc ggaagcttag aacacaacat gggagaagtc gtttttaata ctgggatgac 1622761 aggctatcag gaaattttat ctgatccttc ttactgcgga cagatcgtaa cattaacata 1622821 cccgcttatc ggaaattacg gcattaaccg tgatgatttt gaatccatta ccccttttgt 1622881 caaagggctg atcatcaaag aattatgtga gctgccttcc aactggcgtt cagcatacac 1622941 cttagacgag tatttaaaaa tgaaaaacat tcccggactc cagggaattg atacaaggaa 1623001 gctgacaaga atgatccgca cggcaggcgc gctaaaagga acattcgctt catctgatga 1623061 agatatcgaa gcagtgctga aaagactgaa cgaaacggaa ttgccaagaa atcaagtatc 1623121 ccaagtatca gcaaaaacag catatccgag cccgggaaga ggcaaacgca ttgtcttggt 1623181 tgacttcggc atgaaacacg ggattctaag agagctgaac aaacggaaat gtgacgtcat 1623241 cgttgtgcct tacaacatta cagcggaaga ggtgcttcag ctgaaaccgg acggtatcat 1623301 gctttctaac ggacctggag acccgaagga tgtgcctgaa gcgattgaaa tgattaaagg 1623361 tgttcttgga aaagtgccat tattcggaat atgtctcggc caccaattat tcgcgctggc 1623421 gtgcggggcg aatactgaaa aaatgaaatt cggccacagg ggctcaaacc acccggtaaa 1623481 agagctggct acaggaaaag ttgccttaac atctcaaaac catggatata cagtttcgtc 1623541 tatcagtaaa acagaactgg aagtgacgca tatcgcaatt aacgacgata cgattgaagg 1623601 gctgaagcat aaaacattgc cggcatttac ggttcaatat catcccgaag cctcacctgg 1623661 tcctgaggat gccaaccatc tatttgacag attcatcgaa atgatcgaaa caacagagaa 1623721 agaaggggaa gcggtatgcc aaaacgcgta gacattaaca aaattttagt aatcggatct 1623781 ggaccgatca tcatcggcca agcagcagaa tttgactatg cgggaacaca agcctgtctt 1623841 gctttgaaag aagaaggcta tgaagtcatc cttgtcaact caaaccctgc aacgatcatg 1623901 acagatacag aaatggctga ccgggtttac atcgaaccgc tcacacctga attcctgaca 1623961 cgaatcatca gaaaagagcg cccggatgcc attcttccta cactcggagg ccaaaccggt 1624021 ttgaatcttg cggttgagct ttctgaaaga ggcgttttgg cagaatgcgg cgtcgaagtg 1624081 cttggcacga aactgtctgc gattcagcaa gctgaagacc gtgacttgtt cagaacatta 1624141 atgaatgaac tgaatgaacc ggtgcctgaa agtgagatta tccactccct tgaagaagca 1624201 gaaaaattcg tcagtcaaat tggattccct gtcattgtcc gcccggcata tacattaggc 1624261 ggaacaggcg gaggcatctg ctcgaatgaa acagagctaa aagaaatcgt tgagaacggc 1624321 ttgaaattaa gcccggtaca ccaatgtctg cttgaaaaaa gcatcgccgg ctataaagaa 1624381 atcgagtatg aagtcatgag agacagccag gatcacgcca ttgtcgtttg taacatggaa 1624441 aacattgatc cagttggaat ccatactgga gacagtattg ttgtcgcgcc gagccaaacg 1624501 ctcagcgatc gcgaatatca gctcttgcgg aatgtatcgt taaaactgat tcgcgcgctt 1624561 gggatcgaag gcggatgtaa tgtccagctc gccttagatc cagacagctt ccaatattac 1624621 attattgaag taaatccgcg tgtcagccgt tcatctgccc ttgcatcaaa agcaacgggg 1624681 tacccgattg caaagctcgc tgctaaaatt gcagtcggac tttcattaga tgaaatgatg 1624741 aacccggtga caggaaaaac atatgcagca tttgaacctg ctcttgacta tgtcgtatcc 1624801 aaaattccgc gctggccgtt tgataagttt gaatcagcaa acagaaagct tggcacgcaa 1624861 atgaaagcga caggtgaggt catggcaatc ggccgcacgc ttgaagagtc attgctgaag 1624921 gcagtgcgat cactggaagc ggatgtgtat catcttgaat tgaaggacgc cgctgacatt 1624981 tcagatgagc ttcttgaaaa gcgaattaaa aaggccggtg atgaacgctt attctactta 1625041 gctgaagcgt acagaagagg ctacacggta gaagacctcc atgaattttc cgctatcgat 1625101 gtcttcttct tgcataagct gttcggaatc gtacagtttg aaaaagaatt gaaggccaat 1625161 gcgggcgata cagatgtgct gagacgggca aaagaactcg gcttctctga tcagtacatc 1625221 agccgtgaat ggaaaatgaa agaatctgag ctttacagct tgagaaaaca agcggggatt 1625281 gcgccggtat tcaaaatggt agatacatgc gcggcggaat ttgagtcaga aacgccatac 1625341 ttctatagca catatgaaga agaaaatgaa tctgtcgtta cagataagaa aagtgtgatg 1625401 gtgcttggtt cgggtccgat tcgaatcggt cagggtgtcg agttcgacta tgcgacggtt 1625461 cactctgtat gggcaattaa acaagcaggc tatgaagcca ttattgtcaa caacaacccg 1625521 gaaaccgttt caacagactt cagcatctca gacaagctgt attttgaacc gcttacgatt 1625581 gaagatgtca tgcacatcat tgacctcgaa cagccaatgg gcgttgtcgt acaatttggc 1625641 ggacaaactg cgattaacct tgctgacgag ctttctgcac gcggagtgaa aatccttgga 1625701 acttcattag aagatttaga ccgtgccgaa gaccgggata aatttgaaca agcgcttgga 1625761 gaacttggtg ttcctcagcc gcttggcaaa acagcgacat cagttaatca ggcggtaagc 1625821 atcgcaagtg atatcggtta tccggtactg gtacgccctt cctatgtact tggcggccgg 1625881 gcgatggaga ttgtttacca tgaagaggaa ctgcttcatt acatgaaaaa tgcagtcaaa 1625941 atcaatccac agcaccctgt attaattgat agatacttga ccggaaaaga aattgaagtc 1626001 gatgcagtat ccgacggtga aacagtcgtc attccgggaa ttatggagca cattgaacgt 1626061 gcgggcgttc actccggaga ctcaatcgct gtttatccgc ctcagtctct cacagaggac 1626121 attaagaaaa aaattgaaca atacacgatc gcattggcta aagggctgaa tattgtcggt 1626181 ttgctcaata ttcaattcgt cttgtcgcaa ggcgaggtgt acgtgctaga agtgaatccg 1626241 agatcaagca gaaccgtacc gtttttaagc aaaattacgg gtatcccaat ggcgaatctc 1626301 gcaacaaaaa tcattcttgg tcaaaagctg gctgcgtttg gctatacaga gggccttcag 1626361 cctgaacagc aaggtgtatt tgtaaaagcg ccggtcttct cctttgccaa gctgagaaga 1626421 gtggatatta cgttagggcc tgaaatgaaa tcaacaggtg aagtcatggg gaaagattcg 1626481 acacttgaaa aggcgctcta caaagccttg atcgcttcag gtattcaaat cccgaactac 1626541 ggttccgtgc ttttaacagt agctgataag gacaaagaag aagggcttgc cattgctaag 1626601 cggttccacg cgatcggcta caacatttta gcgacggaag gaacggcagg ctacctgaaa 1626661 gaagcttcca ttccagcgaa ggtcgtcgga aaaatcggtc aggatggccc gaacttgctt 1626721 gatgtcatca gaaacggaga agcgcagttt gtcatcaata cgctgacaaa aggaaagcag 1626781 ccggcaagag acggttttag aatcagacgt gaatcagtag aaaatggtgt tgcctgccta 1626841 acatctttag atacggcaga ggcgatattg cgagtgctgg aaagcatgac attccgtgct 1626901 gatcaaatgc cggcagtcaa cacaaatcag gaggcggcag tcactatatg aaaaaagcgt 1626961 atttgacagt atgttctaac cagcaaattg cagaccgggt gtttcaaatg gttctgaaag 1627021 gggagcttgt ccaagggttt acaacccctg gacagttcct tcatcttaaa gtgagcgaag 1627081 cggttacgcc tcttttgaga aggccgatca gcatcgcaga cgtcaacttt gaaaaaaatg 1627141 aagtcaccat catttatcgg gtagatgggg aagggacaag actcttgtca ctgaagcagc 1627201 agggagaact tgtggatgtc ctcgggcctt tgggaaatgg ctttcctgtt aatgaagttc 1627261 aacccggaaa gacggctttg ctggtaggag gcggagtagg tgtgccgcct ctccaagagc 1627321 tgtcgaaacg cttgattgaa aaaggggtaa atgtcatcca cgttttagga ttccaatcgg 1627381 caaaggatgt tttttacgag gaagaatgcc ggcagtacgg agacacgtat gtggcaacag 1627441 ctgacggaag ctacggggaa accggatttg tcacagatgt gattaaacgg aaaaagctag 1627501 agtttgatat cctcctcagc tgcgggccga caccgatgct caaggcgtta aaacaggaat 1627561 atgcccataa agaagtatat ctgtccatgg aggaacgaat gggctgcgga atcggcgcat 1627621 gcttcgcgtg tgtgtgccat acaaacgaaa gtgagacatc ctatgtaaaa gtatgtctcg 1627681 acgggcctgt atttaaagct caggaggtgg cgctgtaatg ctagaggtga aattgccggg 1627741 acttgatttg aaaaacccaa tcattcctgc atcaggctgc ttcggttttg gaaaagaatt 1627801 ttcacgtttt tatgatttgt cttgtcttgg agctatcatg attaaggcta cgacaaagga 1627861 gccgcgcttt gggaatccga cgccgcgggt agctgagact ggtgctggaa tgctcaatgc 1627921 gatcggtctc caaaatccgg ggctggatag tgtgttgcat catgagctgc cgtggcttga 1627981 gcagtttgat acaccgatca ttgccaatgt cgcaggttct caagtcgatg attatgttga 1628041 agtcgcagaa catatcagca aagcgcctaa tgttcatgct cttgaattga atatttcctg 1628101 cccgaatgtg aaaacaggcg gaatcgcttt tggcacgaat cctgaaatgg ctgccgattt 1628161 gacaaaagcg gtgaaagagg tttcggatgt acccgtttat gtgaagctat ccccgaacgt 1628221 ggctaatatc acagaaattg cattagcgat cgaggaagcg ggagcggacg gtcttacgat 1628281 gatcaacaca ctaatcggca tgagactcga tttaaaaacc ggcaaaccga tattagcgaa 1628341 taaaacaggg ggactttcgg gccctgctgt gaagccggtt gccattcgca tggtgtatga 1628401 agtcagccag atggtcaaca tcccgattat cggaatggga ggcgtgcaaa cggctgaaga 1628461 tgccctggaa tttcttctcg cgggagcaag cgcagtcgct gtcggaacag caaactttgt 1628521 gaatcctttt gcatgtccag agattattga acagctccca tctgttttgc tccaatacgg 1628581 ctatcaatca attgaagaat gcatcggaag gagctggaat catgaaaaac aacctgccca 1628641 tcatcgcgct tgattttgcg tcagctgaag aaacacttgc gttcttagcg ccttttcagc 1628701 aagaaccgtt atttgtaaag gttgggatgg agctttttta tcaagaaggg ccatctatcg 1628761 tgaaacaact aaaagaaaga aactgcgagc tatttttaga tctaaagctt catgacatcc 1628821 cgactactgt aaacaaagcg atgaagcgcc ttgccagtct tggagtagac ctcgtcaatg 1628881 ttcatgctgc cgggggcaaa aaaatgatgc aggcagctct cgaaggctta gaagaaggta 1628941 cgccggctgg aaaaaaacgt ccgtcactta tcgcggtaac ccagctgaca agcacatctg 1629001 aacaaatcat gaaagatgaa ctgctgatcg aaaagtctct gattgatacg gttgtgcact 1629061 acagcaaaca ggcggaagaa agcggactgg atggagtggt ctgctctgtt catgaagcaa 1629121 aagccattta ccaagcggtg tcgccttcat ttctgactgt cactccgggg atcagaatgt 1629181 cagaggacgc tgcgaatgac caagttcgcg tagcgacgcc tgccattgca agagagaaag 1629241 gttcatcagc gattgtagta ggacgctcga ttacaaaagc ggaagacccg gtaaaagcct 1629301 ataaggctgt cagacttgaa tgggagggaa tcaaatcttg aaacaaatca tcgcaaaaca 1629361 tctattagac atccaagctg tatttttacg cccgaacgag ccgttcacat gggcaagcgg 1629421 cattttatca ccgatctact gtgacaaccg ccttacgcta tctttcccag aggtcagaaa 1629481 cgatgttgct tcaggtatca gcaagcttgt taaagagcat tttcctgaag ctgaaatgat 1629541 tgcgggaaca gcaactgccg gtattcctca tgctgctctt gcggcggacc atttgaatct 1629601 tccgatgtgt tatgtgagga gcaagccgaa ggcgcacgga aaaggcaatc agattgaggg 1629661 agctgtgcaa gaagggcaaa aaacagtcgt cattgaagac ttaatttcca caggaggcag 1629721 cgtgcttgaa gcttgtgcag ctttacaagc ggccggctgt gaagtgcttg gtgtcgtctc 1629781 aatctttacg tacggacttc ctaaagcgga ggaagccttc gcaaaggcag aactgccata 1629841 ctactcatta accgattatg atacgctcac agaggtcgcg cttgaaaacg gaaatattca 1629901 ttcagatgat ctaaaaaagc tgcaaacatg gaaacgaaat cccgagtcaa aagattggtt 1629961 taaaaaataa aaaataaatt caaatgatgt aaagaggctt caaagccttg ctgtacttga 1630021 aaacaggctg tgaggcctgt ttttttatta atcctataaa aaaagtcggg ttgacttatg 1630081 ttagaattgt gctaaaattt actacaaatc taaaaactta tcaagagcgg ctgagggact 1630141 ggacctatga agcccggcaa cctgcatagt ttgtaaggtg ctacttccag caaaatgaat 1630201 tccattttga aagataaggg ctgcatgctg ttcctgtctt tctttccgcc ggattgaaag 1630261 ttttttattt taagaggtaa aaaggctatc tgtatatcag cagccgcgaa tcacattaca 1630321 tgggaaaaga caaccggcag aaagctactg tttgtttgtc tccgaaagga ggaaagaaga 1630381 aatgttaacg tatgataatt gggaagaacc aacgattaca tttccggaag acgatcctta 1630441 taaaggagcg ctgtcagttt taaaatgggc atacggccat tacggcgatc agcttgttta 1630501 tgcctgcagt ttcggaattg agggaatcgt tctgattgac ttaatttata aagtgaaaaa 1630561 agacgcagag attgtgtttc ttgatacagg acttcatttt aaagaaacct atgaaacaat 1630621 tgaacgagtg aaagagcgtt atccgggtct taatatcatc ctgaaaaaac cagatctcac 1630681 ccttgaggaa caagccgaag aacatggtga caaactatgg gaaagagagc cgaatcagtg 1630741 ctgctatctt agaaaggtcg ttcctttaag agaggcgctt tcaggacatc cagcctggct 1630801 ttccggcctg cgccgtgatc aagggccaag ccgtgccaat acgaatttct taaacaaaga 1630861 tgaaaaattc aagtcagtaa aagtttgccc gcttatccat tggacttgga aagacatttg 1630921 gagatataca tcccggaatg aactggacta caatccgctt catgaccaag gctatccaag 1630981 tattggctgt gcgccttgca cttctcccgc ttttacagca gaagatttgc gctcaggcag 1631041 atggaatggt atggcgaaaa cagaatgcgg actgcatgaa taaggagctg caaaatggaa 1631101 ttagccgcta ttttatttag cttgtttttc gcgatgaata ttggtgcaag cggcgctgca 1631161 gcttcgatgg gggttgctta cggctccgga gccatcaaaa agaaaactta cgctttgatc 1631221 ctatgcgcag tcggtgtctt tgccggggcg gtcattggcg gaggcgaggt tgtaaaaaca 1631281 atcagctccg gcattattcc tgagcagacg attacactga cgattgtttg catcattatt 1631341 ggagctgctg ccctgtcgct ctttactgct aatctgctcg gcattccttt gtcgacaagt 1631401 gaagtaacag tcggcgcggt tgtcggcgtg ggagtggctt ataaagtatt gtttgtgaac 1631461 aatcttctga tcattgtgtc attttgggtt tttgtcccgc tgttcgcttt cggcttcacc 1631521 tatttcgtat ctaagctgtt tcgttatttt aagattgaag taaaatcttc taaaaagcaa 1631581 aaaatcctcg gcattgtttt gttagttgcc ggatttttcg aagcattctc tgccggcatg 1631641 aataacgtgg cgaatgctgt tggcccgtta gtagctgccg gtgtgcttga tgtcggaaaa 1631701 ggaaccttgt atggaggagc ttttgttgct cttggcgcac tgttattagg ccggcgagtg 1631761 ctagaaacaa acgggaagaa aattacgagg ttctccaaag gggaaggcat tctcttatcc 1631821 ggtacaggag cgggactggt gatcatcagt tctgtatttg ggatgccggt gcccttggcg 1631881 caagtcacgt catcgtctat tatcggaata ggcatggcga aaaacggtcc gaacgtgttc 1631941 cataaacaag ttgttcaaac gatgctgaag gtatggatcg tatcgccgtt tttatcttta 1632001 tcgatttctt atctgcttgt atccttgttt ttaaaagcag attattattc gatctttatc 1632061 atggtaagtg tgcttttagc ggcgggcggt gccatcagcc tgacaaaggc cattcgtaaa 1632121 gagagacgct cagtccacga acaaggcggg ggaatctgat cattaatctg agtaatttta 1632181 taagttaact aggaggagat ggatattatg agcttagcac cacacggagg aacattagta 1632241 aacagagtag atgaatcata tgatgtgagc ggcattcaaa aagaaattga acttgattta 1632301 atttctttcg cggatttgga attgatcggt atcggtgcat acagcccgat tgaaggtttc 1632361 tttaatgaaa aagattacgt atcagtggtc gaaaacatgc gtctttcttc cggcgttgtc 1632421 tggtctcttc caatcacgct tccggtcgat gcgcaaaaag cagcggaact gtcacttggt 1632481 gaaacggtaa agttaacgta tgaaggagaa acttacggcg ttatccaaat cgaagacctg 1632541 tacgtgcctg acaaacaaaa agaagctgtc aatgtgtaca aaacagatga acaggagcat 1632601 cctggtgtta aaaagctgtt cagccgcggc aatacatatg tcggcggacc gattacgttg 1632661 attaaaaaag cttcaaaaca gttccctgaa tttacatttg aaccgtcaga aacgagacgc 1632721 cagtttgcgg aaaaaggctg ggaaaccatt gtcggtttcc aaacaagaaa ccctgttcac 1632781 agagcgcatg aatacattca aaaaacggct cttgaaacag tagacggctt gttcttgaat 1632841 ccgttagtag gtgaaacaaa atctgatgac attccagctg atgtacggat ggaaagctac 1632901 caagtgcttc ttgatcatta ttacccgaaa gatcgtgttt tccttggtgt ctttttagcg 1632961 gcgatgcgtt atgcaggccc gagagaagca attttccacg cgcttgtcag aaagaactac 1633021 ggctgcacac atttcatcgt cggccgtgat catgcaggtg taggcgacta ttacggaaca 1633081 tacgaagcac aggaactgtt tgacacattt aaacctgaag aactcggaat tacaccgctg 1633141 aaatttgagc acagcttctt ctgtaaaaaa tgcggaaata tgggaacagc aaaaacttgc 1633201 cctcatggca gagagcatca cgtcatttta tcaggcacta aggtaagagg tatgctgaga 1633261 gacggtgtgc tgccgcctgc tgaattcagt cgaaaagaag tagtagaagt gttaatcaaa 1633321 gggatgaaga aaaaagaaga agtaggcgta tcttaaggag gactggcagt gacaaatcgc 1633381 gatattgtat ggcatgaagc ctctatcaca aaagaagagt atcagcaaaa aaacaagcat 1633441 aaaagctcca ttctctggct gacagggtta agcggctcag gcaaatcaac cattgccaac 1633501 gccgctgcga gagaattgtt tgagcaaggc taccaagtca ttgtgctgga cggggataat 1633561 atccgtcacg gcctaaatag ggatcttggt ttttctgatg aagaccgaaa agaaaacatc 1633621 cgccggatcg gagaggtggc gaagcttttt gttcagcagg gaaccattgt gattactgct 1633681 tttatctctc ctttccgcga ggacagacaa caggttcgcg agcttgtgga agcgggcgaa 1633741 tttaatgaag tctacattaa atgcgacctt gatatttgtg aacaaagaga tccgaaaggg 1633801 ctttacaaaa aagcaagaaa cggcgagatt ccgttcttta caggaattga ttctccttat 1633861 gaagaaccgg aagctccaga gctcgttctt gattcaggac agcatgaccg tgaagcgtgt 1633921 aaaaatcagc tgatcgagtt tgttaaacaa aaattgagct gaatatgatc tgctgcgttc 1633981 ttctcagatg ccggaatgca agcgagaaca tcatcacagc gaatcttctg gaagaactcg 1634041 aatagatcgg gggaaatacg atggggaaag tatatattgt aggagcgggt cccggtgacc 1634101 ctgatctgct gacaattaaa gcgctgaaag ccattgaaaa agctgatgtc atcttatatg 1634161 acagattagt aaataaagag attttacaat atgccaaaga gcaagcagac ctgatctact 1634221 gcgggaagct tccggatttt catacgatga agcaggaaac catcaatcga tttcttgtga 1634281 agtatgcgca aaaagggaaa atggttgtca gactgaaagg cggagaccct tttgtgttcg 1634341 ggagaggagg ggaagaagcg gaatgcctct ctgaaaatgg aattccgttt gaaatcattc 1634401 ccggcattac gtctggaatc gcggcagccg cttatgccgg gattcctgtt acccatcggg 1634461 atgcgggctc taacgtcgct tttgtaacgg gtcactataa aaaagaagaa gattttgagg 1634521 aaaagtggaa agcgctggct acaggaattg atacacttgt catctatatg ggtatcaaaa 1634581 acgtgcagca gattgaaaga aaactccttg aaaatggccg ggacggttct acgccagcag 1634641 cctttattca ttgggggaca acggacaagc aaaaatctgt tttttgtaca gttgacaccc 1634701 tttcagaaac ggtgataaaa gaaaacatta caaatccgag tttaattgtc attggaaatg 1634761 ttgtaaatta tcactataag ctggaatggt ttgaatctga actaaaaaaa caagatttaa 1634821 gcgaggcgtt gtaaaaatga aacaagcaat tttatatgtc ggccacggca gccgggtcaa 1634881 aaaagcgcag caagaagccg cagccttttt ggaaggatgc aaggcccaca tctctgtgcc 1634941 agtacaagaa atcagctttt tagagcttca ggagccgaca attgagacag gatttgaagc 1635001 atgtgtgaag caaggtgcca ctcatatcgc agtggtgcct ctgcttcttt taacagctgc 1635061 gcatgcaaaa catgatattc cggaagaaat tgtccgtgtt gcatctcgat atccatcagt 1635121 ccgtatttca tacggaaagc cgatcgggat tgacgaagaa gtagtcaagg ctgtatatca 1635181 ccgaatgaaa gacataggtg ttccgtatga aaatgccaga gtggtgctca tcggaagggg 1635241 aagttcagat ccagacgtca aaagagacgt aaccggaatt gctaatcttc ttcaggaaat 1635301 ggttccagtg aaggaagtca ttccgtgctt tttgacagca tgcggcccta attacaaaga 1635361 ggttttttca gaacttgaaa aagatgacgg cataacaacc tttatcgttc catatttgct 1635421 ttttacgggt atgctgatga atgaaatcga acgagaggtt cagaaattaa aagcccataa 1635481 tccgaacgtc tacctctctt cctatatcgg ttttcatcct catgtgaaaa acgcattttt 1635541 gaaccgtgtg agagaaactg cggcaaattc tgagggacaa tttgattttg atggaggttc 1635601 atatgcttcc gctgcacatt agcctggaaa agaagaaggt tgtgattgcg gggggcggaa 1635661 gcatcgctct cagaaggctg aaaacggtga tttctgaggg agctgatata acgcttgtca 1635721 gtccggatgt ggaaccggaa atcaagcaaa tggcagaaga gcggcgtatc aaatgggaaa 1635781 aacggacaat tgaaaaagaa gattatctca atgctttctt cattattgct gcgacggata 1635841 atgcggcagt gaacaaagaa attgcccaat ccgcttcgcc ttttcagctt gtcaattgtg 1635901 tcagtgacgc tgagcttggc aatgtatata tgccgaaaat cgtaaaaaga gggcatgtca 1635961 ctgtgtctgt ttctacaagc ggagccagtc caaagcacac gaaagagctt gctgaaaacg 1636021 tggataagct gattgacggc gattttgttg ctgaagtgaa caggctttat cagatgagaa 1636081 gaaagaaata agccagagca tacaaatgct ctggcttttc tttatgcggc tcagcttttt 1636141 ttgagcttga tgacagtatc agcatcaggc gtgacaaaga cggtatgctg gctgtcataa 1636201 gtgacgaaac cgggtttcgc gccgtttggt tttttgacat gcctgatttt tgtataatct 1636261 acaggcactg aacttgaatc tttagctttt gaaaaataag ctgcaattgt cgcggcttcc 1636321 atgattgttt gctcatcagg ttcgctgctt ctgatcacaa cgtgggagcc gggaatgtcc 1636381 ttcgtgtgaa gccagatatc gtctctggcc gccactcttg tcgttaaata ttcattttga 1636441 cgattgttct tacccactaa aattgtcagc cctgaggtgg attcatatgt ttctaacacc 1636501 ggattgtgcg gtttttgctt tttctggcct ttttgctgct tagggcgtaa atatttgccc 1636561 tcaacaagct cttccctgat ttcgctgata tcccggggag aagcggacga aagctgctga 1636621 atcagctgat caaaatattc gatctcttcc tgtgccagcc tgatttgctc ctcgacaact 1636681 gcgaccgaat ttttcgcttt ctgatacttc gtgaaatagg cctgtgcgtt ttcagaaggc 1636741 gttttgttcg ggtttaaagg aatcgtgatt gtcgggcttt cttcatcata ataattgatg 1636801 acctcagcct gtttatcacc ttttttcagc atatataaat tagcggttaa aagctctccg 1636861 taaagctgaa attccttcgc gttttccgaa tactccaggg ttttctctaa ttttttgatt 1636921 ttgttggcat tcttcttccg ttcgttcaca acaaaacgct caagatcctg agcctgttgc 1636981 ttaacccggt ctcgttcagc ttttccgaaa taaaaacggt cgagcagttc gcttaatgaa 1637041 tcaaaacggc gcgcttcgcc ctttagatga gtcagctcca gcagataaaa atattccttt 1637101 ccgtttacag tcgtaatgtt gggaatgaaa cggtgctctt tcacttcggc aaacagtgcc 1637161 agcaacgctt ttggcagtgt gactttgttg gcaaggcctg ctctgtgaac cgcttctttg 1637221 gcgaaaagcg gagacacgcc tgaaaagtgg tcgacaattt gtttatcaag ccttccttct 1637281 tgaaagctga ggtgacgcaa aatatcatct tctgacgcct caagaggcga tattttgtcc 1637341 tgagcaggcg gaagcttata atcttggccg ggcagtactg tacggtagct gttcattgac 1637401 ggtgataaat gcttaagtcc gtcgataatc acattttctg ctgcgtcagt caaaatgata 1637461 ttgctgtggc ggcccataat ttctacataa agctttcgta cggtttcatc gccaatttcg 1637521 tttcggcttt tgatatgaaa aatcataatg cggtctaagc ccgcttgttc aattttctca 1637581 atgaatccgc cttcgatatg ctttctcagc aacatgcaaa acattggcgg ttcgcttgga 1637641 ttttcataag cttgtgccgt gatatgcacc cgtgaatagc tcggatgtgc cgataataat 1637701 agtttttggt tttttccctt ggcacggatg tggaaaatca catcgtgctt atatggctga 1637761 tggatttttg taattcgtcc gcccattatt ttctcgttaa gttcgtgtgt cattccgtat 1637821 gtaaacatgc catcaaacga catatgcaat acaccctctc attcttcctg cattcgataa 1637881 ttatagcatg aaatgggacg agtcagaata agcatgctta tagagtgata tctctataag 1637941 agagcagggg agtggacgag cggaatgaag tttcatgaaa tgggacaaac agatttacta 1638001 gaggcaacca atacgtccat gaaacaagga ttaacagaaa aagaggtaaa aaaacgcctt 1638061 gacaagcatg gaccaaacga gctgcaagaa gggaaaaaaa cttcagcgct tctcttgttt 1638121 ttcgcgcagt tcaaagattt tatggtgctt gtgcttctgg cggcaacgtt aatctcagga 1638181 tttcttggtg aatatgtaga tgcggttgcg attattgcga ttgtgtttgt gaatggcata 1638241 ctcggtttct ttcaagaaag gcgtgctgag caatctcttc aggctttaaa agagctttca 1638301 acaccgcacg tcatggcact cagggaagga agctggacaa agattccttc taaggaactg 1638361 gtgccgggtg atattgtgaa atttacgagc ggggacagaa ttggcgcaga cgttcgaatt 1638421 gttgaagcga gaagccttga aatagaagaa tcagcgctaa ccggggaatc aatcccggtt 1638481 gtgaagcatg ctgataaatt gaaaaaaccg gatgtttcac tcggcgatat taccaatatg 1638541 gcatttatgg gtacgattgt gacccgcggc agcggtgtcg gggttgtcgt cgggacagga 1638601 atgaatacgg ctatggggaa aattgccgac atgcttgaat cggcagggac attgtcaacc 1638661 ccgctgcaaa gaagactgga gcagctcggg aagattttga ttgttgttgc attgcttctg 1638721 accgtacttg tcgttgctgt cggtgttatt cagggtcatg atctgtacag tatgttttta 1638781 gcaggtgtct cgttagcggt agccgctatt ccggaggggc tgccggcgat tgtgacagtg 1638841 gcgctttcgc ttggtgtaca gaggatgatt aaacaaaaat ccattgttag aaagcttcct 1638901 gctgttgaaa cgcttgggtg tgcgtctatc atttgctcag ataaaacagg gacaatgacc 1638961 caaaacaaaa tgacagtgac gcatgtctgg tccggaggga aaacatggag agtggcaggg 1639021 gccggctatg aaccgaaagg aagcttcaca ctaaacgaaa aagagatcag tgtcaatgaa 1639081 cataagccgc ttcagcagat gcttctgttc ggagcgcttt gtaacaactc caatattgag 1639141 aaaagagacg gcgaatatgt gcttgacgga gatccgacag agggagcgct gctcaccgcg 1639201 gcaagaaaag gcggtttttc aaaggagttt gttgaatcta attacagagt gattgaagaa 1639261 tttccgtttg attccgcacg gaaaatgatg actgtcatcg tagagaatca agacagaaag 1639321 cgctatatca ttacaaaagg tgcgccggat gtactcatgc agcgatcttc ccgtatttat 1639381 tatgatggct cagcggctct tttttcaaat gaaagaaaag cagaaacaga ggcggtatta 1639441 agacatttgg catcacaggc gctcagaacg atagcggtcg cctacaggcc gataaaagca 1639501 ggcgaaacac cgtcaatgga gcaggcggaa aaagatctga ccatgcttgg cctttcaggt 1639561 atcattgatc ccccgcggcc ggaagtcaga caggcgatta aagaatgccg tgaagcggga 1639621 attaagaccg tcatgattac aggtgatcat gtagaaaccg ctaaagcgat agcgaaagac 1639681 ttgcgcctcc ttccgaaaag cggcaaaatc atggacggca agatgctgaa tgaactttct 1639741 caagaagagc tttctcatgt ggtggaggat gtgtatgtat ttgcccgcgt ttcccctgaa 1639801 cataaactaa aaatcgtaaa agcctatcag gagaacgggc atattgtggc gatgacggga 1639861 gacggcgtca atgatgctcc tgccattaaa caggctgata tcggcgtctc tatgggcatt 1639921 accgggacag atgtggccaa agaagcatca tctcttgttc tcgtggatga taattttgcg 1639981 acgattaaat cagcgataaa agaaggcagg aacatctacg aaaatatcag gaagtttatc 1640041 agatacctgt tggcgtctaa cgtcggagaa atccttgtca tgctgtttgc gatgctgctt 1640101 gcccttcctt taccgctggt tccgattcag attttgtggg tcaacttggt gacggacgga 1640161 ttgccggcaa tggcgctcgg catggatcag ccggaaggag acgtcatgaa gcgcaagccc 1640221 cgtcatccga aagaaggggt atttgcccgc aagctaggat ggaaggtcgt ttccagagga 1640281 tttttaatcg gagttgccac tattttagcg tttatcattg tgtaccaccg caatccggaa 1640341 aacttggctt atgcccagac gatcgcgttt gccacattgg tgctcgctca gcttattcac 1640401 gtgtttgact gccgcagcga aacttctgtt ttctctagaa atccgtttca aaacctgtat 1640461 ttaatcggcg cggtattgtc atccattttg ctgatgcttg tagtaatcta ctatccgccg 1640521 cttcagccga ttttccatac tgtagccatc acgccggggg actggatgct cgtcatcggt 1640581 atgtccgcca tccctacttt tttgctggcg gggtcacttt taacaagaaa aaaataaatt 1640641 catatgatat aatcttaggg gtaatagcgt gtctattgcc cttttattat gagaacaggg 1640701 aagaattggg tgttttaaaa tgatacgaag tatgacaggc ttcggcagtg caagcaaaac 1640761 acaagacgat ctctctgtaa gcgttgaact taaatctgtg aactacagat ttaaagaagt 1640821 gaacgctcgt ttgccaaggc ctttgctata ttttgaagat aagctgaaac agaccattct 1640881 gcagcatatt cagcgcggaa gaattgagct tttcgtatcc gttgacagcg atatgcttgt 1640941 tgagaaaagg cttgaaattg attggccgct gctcgatgag tttgtcgcag ccgcgagaga 1641001 tatgaagaag cggtatcaat tgtctgcaga gcccgatgta atggatttct ttaagcttga 1641061 tcatgtcgtc caggttcatg aagaacagac gcaaaatgac aagctggagg cgttgatcat 1641121 cgatgctgca gaagaagcgg taaaaggtct ctgtgaaatg cgtgaaaaag aggggctgct 1641181 cttagcgaaa gactgcctga tgcatattga tcagcttgaa gagctggtga gagaaactga 1641241 attgctggct gcagatgtcg tatctcgtta ccgggaacgg ctgtatgcca gaatcaaaga 1641301 atggactgaa gacgtattag acgagagccg gcttgtaaca gaatgcgcta tttttgcaga 1641361 ccgctctgat atcactgaag agattacaag gctgaagagc cacttcgccc agtttcgtga 1641421 tatattagct agtggcggag ctgtcgggcg caaactcgac tttcttgttc aggagctcaa 1641481 tcgggaagca aatacgatcg gctcaaaagc aaatgatcat cagatcacaa agcttgtcgt 1641541 tgaaatgaaa agttctattg aaaaaataaa agaacaagtg caaaatatag aatagtgact 1641601 gtgcgtattg tttacagacg gtcttactag gctaaactag agacgtctat tttacagggg 1641661 gaacgtagaa gatgacgatt aaactgatta atatcggatt tggcaatatc atctccgcca 1641721 atcggatgat ttcgattgtc agcccggagt ctgcgccaat caaacggatg attcaggatg 1641781 caagagaccg cggaatgcta attgacgcta catacggacg aagaacccgt gcagttgtcg 1641841 tcatggatag tgatcacatt atcttatctg ccgtccagcc tgagacagtt gcacacagac 1641901 tttctgttaa agaagaaatt atggatgaag ggcaggggta attgccgcat gaaagaaaga 1641961 gggttattaa tcgttctctc aggtccctca ggagttggta aaggaacggt tcgacaagcg 1642021 atcttttcgc aggaagacac aaaatttgaa tattcgattt cagtaaccac aagaagtcca 1642081 agagagggcg aagtgaacgg agtcgattat tttttcaaaa caagagacga attcgagcaa 1642141 atgattgcgg acaacaagct gcttgaatgg gcagagtatg tcggcaatta ttacggcacg 1642201 ccagtcgatt atgttgaaca gacgcttcaa gatggaaaag acgtcttttt agaaattgaa 1642261 gttcaagggg ctcttcaagt gagaaatgct ttcccggaag gcctgtttat tttccttgcg 1642321 cctccaagcc tttctgaact gaaaaacaga atcgtgacac gaggaacaga aacagacgct 1642381 ctgattgaaa atcgaatgaa agccgcaaaa gctgagatcg aaatgatgga tgcttatgac 1642441 tatgtcgttg aaaacgataa tgtcgaaacg gcttgcgata aaatcaaagc aatcgttctt 1642501 gctgaacatt tgaagcgtga acgcgttgca ccaagatata agaaaatgct ggaggttgaa 1642561 taatcaatgt tagatccgtc aattgattct ttaatgaata aattagattc aaaatatacg 1642621 ctggtgactg tttctgcgag acgtgcccgt gaaatgcaaa tcaaaaaaga ccaaatgatt 1642681 gaacatacga tttcacacaa atatgtaggc aaagctttag aagaaattga tgcaggcctg 1642741 ctttcgtttg aaaaggaaga ccgcgaatag tagcacaagt agcaacctat atcatgtagg 1642801 ttgttatttt tttccgtgcg gttttgtaaa gtgcagaggg ggagaattca ttgcttaaca 1642861 atcgaaatgt gttactttgc gtgagtggag gcatcgctgt ttataaagcc tgtgcgttaa 1642921 cgagcaagct ggttcaggca ggagcaaatg tcaaagtgat tatgactgaa tccgcttgcc 1642981 gattcgtttc accgctgaca tttcaggcat tgagccgcca cgaagtctat acagatacat 1643041 ttaaagaaca aaatccaagc gtcatttctc atattgatgc cgcagactgg gccgacttga 1643101 ttatcgtagc gccggctacg gctaatgtga ttggaaaact ggcaaacggc atcgctgatg 1643161 atatgctgac gacaacattg ttggcagcaa cggctcccgt ttggatcgcg ccggcaatga 1643221 acgttcatat gtatgaccac ccggcagtca aacgaaacat ttctgttctt tatcaggacg 1643281 gttattgttt tattgagcca agtgagggct atttagcatg cggttacgta ggaaaaggca 1643341 gattggaaga gccggaaaac atcgtaaagc tggccgaaaa acattttgct gaagaaacat 1643401 ccgctccttt agaaggcaag catgtggtca ttacagccgg cccaacgcgg gaagcgattg 1643461 atcctgtccg gttttttacc aataaatcga cgggcaaaat gggctacgca ctggcggagg 1643521 ctgctgttca gctcggcgca cgggtaatct taatttctgg gcctgtttca cttgatcagc 1643581 ctaaaggcct tgctgagttt atccctgttc aatcggctgc ggatatgcgc gaagctgtgc 1643641 tctctgtgta tgacgcaagc gatatagtca ttaaaacagc tgcggtagcc gattttacgc 1643701 cgaaaacagt atttgaccat aaaatgaaaa aacaagacgg cggcatgacc ttagaactga 1643761 aaagaacagt cgatattttg aaagaattgg gcgagaaaaa gaaagagcag attttggtcg 1643821 gatttgccgc cgaaacacaa gacattgaac actatgcacg taaaaagctc gccgctaaaa 1643881 accttgattt gattgtggca aatgatgtga aagcaaatgg ggccggtttt ggtgctgata 1643941 cgaatatcgt gacaatcttt ttcaaagacg ggcataaacg cgaactcccg attatgtcta 1644001 agctcgatgt ttcttttgaa atccttcagg agatcgcagc cctctcaaaa caaaccggag 1644061 agcgctcatg aattttgcag aagtcatcgt tgatgtcagc accaaaaata tagacaggcc 1644121 ttttgattat aaaatcccag accatctgaa gggcatgatc aaaacgggga tgcgggtcat 1644181 tgttccgttt ggcccccgta agattcaagg gtttgtgaca gcagtcaaag aagcatctga 1644241 cctatcggga aaatctgtca aggaagtaga ggatttatta gatcttacac ctgttctgac 1644301 agaggagctt atgattctgt catcatggct gtcagacaaa acgctgtctt ttaaaataac 1644361 ggcgcttcaa gcaatgctgc ctgccgcctt aaaggcgaaa tatgaaaaag aattaaaaat 1644421 tgcacacgga gccgatcttc cgccgcaagt ggaacggctg ttttctgaaa caaagacgct 1644481 gctgtattca gatatacccg atcatgagac gctgaaactg attcaaaggc atgttcaaaa 1644541 aggggacatt gacgtgacgt ataaagtcgc gcaaaaaacc aataaaaaaa tggtcaggca 1644601 tattcaggca aatgcgagta aagaagagct tgctaagcag gctgagggat tgtcccgcca 1644661 agcagcaaaa cagcaggcga ttcttcactt tctcatctct gagccggaag gtgtgaaaat 1644721 tcctgcggcg gaattgtgca aaaaaacgga cacgagctct gcaaccatca aaacccttat 1644781 ccaaaaaggg cttttgaagg aaagctatga agaggtttac agagatccct atcaggacaa 1644841 aatgttcaaa aaaacagagc ccctgccgct gacagacgaa cagagggctg ccttcgagcc 1644901 catacgcgag acattggaca gcgatgagca taaagtgttc ctccttcacg gcgtgacagg 1644961 aagcggaaaa accgaaattt atctgcaatc aattgaaaaa gtactggcga aaggaaaaga 1645021 agccatcgtc ctcgtaccgg aaatatcgct gacgccgcaa atggtcaacc gcttcaaggg 1645081 ccgcttcggc tcccaggtgg cagtcatgca cagcggttta tccacaggag aaaaatatga 1645141 cgagtggcgt aaaatccacc ggaaggaagt acggcttgtc gtcggtgcca gatccgccat 1645201 ttttgctccg tttgaaaatc tcggaatgat aatcatcgat gaagagcacg agtcttccta 1645261 taaacaggaa gaaatgccgc gctatcatgc gaaagaggtg gcaatcaagc gggctgagca 1645321 tcacagctgc ccggttgtat tagggagtgc tacgccgaca ttagaatcat atgctagagc 1645381 gcaaaagggc gtatacgagc ttctttcact gaagcaccgt gttaaccatc gggtgatgcc 1645441 cgaggtttcg cttgtcgata tgagagagga gcttagaaac ggcaatcgct cgatgttttc 1645501 agttgaattg atggaaaagc ttgaagaaac gattgccaag ggtgagcagg cggtgctgtt 1645561 tttaaataag aggggctact cttcctttgt gatgtgcagg gattgcggct atgtcccgca 1645621 atgcccgcac tgcgacattt ccatgacgta tcatcgttac ggccaaaggc tgaaatgcca 1645681 ttattgcgga catgaagagc ctgttccgca cacttgtcct gaatgcgcaa gcgagcatat 1645741 ccgctttttc ggaacgggaa cacagcgagt ggaggaagag ctgacaaaag tgctgccaag 1645801 tgcgagagtg attcggatgg atgttgacac gacatcacgg aaaggcgccc atgaaaaatt 1645861 actgtcagct ttcggagaag gaaaagcgga tattcttctc ggaacgcaaa tgatcgcgaa 1645921 agggcttgat tttccgaatg tcacgcttgt cggagtgtta agtgctgata caacacttca 1645981 tattcctgat ttcagatcgg ctgaaaaaac atttcagctg ttaacgcaag tcagcggccg 1646041 ggcaggcagg catgaaaagc ccggccatgt catcattcaa acgtatacac cgtctcatta 1646101 cagtatccag ctgacgaaaa cacacgatta tgaaacgttc tatcagcatg aaatggcgca 1646161 caggagagag caatcctatc cgccatacta ctatttggct cttgtgactg tttctcatga 1646221 ggaagtggcg aaagcagcgg ttacagctga aaaaatcgct cattttttga aagcaaactg 1646281 cggagctgac acgaaaattc tcggaccaag cgcgtcgccg atagccagga tcaaagatag 1646341 atatcgctat caatgcgtga taaaatacaa acaggaaacc cagttatccg ctttattgaa 1646401 gaagatactg gaacattata aacgcgaaat tgaacaaaaa catgtaatga tttcaattga 1646461 tatgaatcct tatatgatga tgtaagatct cacgtcttgg agggtaacaa attggcagta 1646521 aaaaaggtcg tcacacatcc tgcggaggtt ttggaaacac ctgcggaaac cgtgactgtt 1646581 tttgataaaa agctaaaaaa actgcttgat gatatgtacg acaccatgct tgaaatggat 1646641 ggtgtcggac tggcagcgcc gcaaatcggc attttaaaaa gagcggccgt cgtagaaatc 1646701 ggggatgaca gagggagaat tgatctcgtt aatcctgaaa ttttagaaaa aagcggcgag 1646761 caaaccggaa ttgaaggatg cttgagcttt cctaacgtct atggtgatgt cacacgtgcc 1646821 gattatgtca aagtgcgtgc gtttaaccgt cagggaaaac cgttcattct ggaagcgcga 1646881 ggctttttag caagagccgt gcagcatgaa atggaccact tagacggtgt gctgtttaca 1646941 tctaaaataa gtaaatacta tacagaagat gaactagcgg atatggaagg atgatttgat 1647001 gacgagaatc gtatttatgg gaacgccgga tttttcagtt cctgttttaa gaaccctgat 1647061 agaggacgga tatgaagtag tgggggtcgt cacacagccg gaccgtccga agggcagaaa 1647121 aaaagtactg acacctcctc cggtaaagga agaggcattg cgccacggca tcccggttct 1647181 tcagccggaa aaagtcagat tgacagaaga aattgaaaaa gtgctggcat taaagcctga 1647241 cctgattgta acggcggcat tcggacaaat tttgcctaaa gagcttctcg acagtccaaa 1647301 atacggctgc attaacgttc acgcatccct tttgccggaa ctgcgcggcg gtgctccgat 1647361 ccattattcc attctgcagg gaaagaagaa aaccgggatt accattatgt atatggtaga 1647421 aaaattggat gcgggcgata tgatctcaaa agtggaagtg gacattgaag aaaccgacaa 1647481 tgtcggaaca ctgcacgata aattaagcgt tgctggcgcg aagctattgt ctgaaacggt 1647541 tccaaacgtt attgccggca gcatatcacc tgaaaagcag gatgaagaga aagcgacgta 1647601 cgcgcctaac attaaaagag agcaagagct gctcgactgg tccagaacgg gcgaagagct 1647661 ttacaaccag atccgcggct taaatccatg gcctgttgct tatacgactc taaacggaca 1647721 aaacttgaaa atatgggcgt cgaaaaaaat agcggcacca acaacagctg agcccggcac 1647781 agtcgttgca gttgaaaagg aaggaattat cgttgccaca ggtaacgaga cggctctgtt 1647841 attaaccgaa ctccagccgg caggcaaaaa acgaatgaaa ggcgaagact ttgtgcgagg 1647901 cgctcatgtt gaagccggtg atgtgttagg agtaaacaat gaaaaaaact agtgttcgtg 1647961 acatcgccct tgaggcgctg atcaaattag aacaaaacca ggcatacagc aacctgctgc 1648021 tgaaatcggt cattaaatca aatgaactga gtgatcagaa cagagggctt ttgactgaac 1648081 ttgtctatgg tacattacaa aataagatcg cgcttgatta tatgcttaaa ccgtttatca 1648141 ataagcctca aaaggtaaag ccgtgggtga ttcagcttct tcgcctatcc ttatatcaaa 1648201 tggagtattt ggagaagatt ccagacaggg cagccattca tgaagcggtt gagattgcta 1648261 aaatccgcgg acacaaaggc attgcttcat ttgtcaacgg cgtgctccgt tctattcagc 1648321 gcgaaggtgt tccatccttt gacgcgatcg aagatcctgt ccgccggctg gcgacagaaa 1648381 caagccatcc ggaatggctt gtgaaagagt gggcggatgc gtatggattt gaagctgcgg 1648441 aaaagatttg ccgcatccat ctcattccgc cgaaacagac gctgcgtgtc aatcaaatga 1648501 aagcagacag agctgagctg cttgaccaaa tggctgctga gggaatcgaa gttgaaaaag 1648561 gcgacctcgc tgaagatgct gtgaagctct taaagggaac aattgccgga actcatttct 1648621 tccaaaacgg cgaagtttct atccaggatg agagctccat gctcgtcgcc cgcgcccttg 1648681 atcctaagtc agatgaaaca gtgcttgacg cgtgtgcggc gcctggcgga aagtcggctc 1648741 atatcgcaga attaatgaag aacaagggga gcgttacgtc gcttgatctt cacaaacata 1648801 aagtgaagct gatcaaagaa gcggcagatc ggcttggcct gacaatcatt catgcggaaa 1648861 caatggatgc tagaaaagcg ggggaaacgt ttgaaaacga acagtttgac cgaatattgg 1648921 tcgatgcccc gtgctcaggt ttcggtgtta tcagaagaaa gccggacatg aaatacacga 1648981 aaaaacctga cgacagcgcc cgtctagctg aaatccagct gtcgatcttg agggaaatcg 1649041 caccattagt aaaaaaaggt ggcactcttg tctacagtac gtgtacaatg gaccggacag 1649101 aaaatgatga agtaatacat gcgtttatac aagaacatcc tgattttgaa cccgatttgt 1649161 ctcttgaaaa gcggctgcct gaaaaggtga gaccctttgt tcgggatgga aggcttcaaa 1649221 tccttcctca ttatttcgga acagatggtt tctttatttg cagcatgaga aagaagggat 1649281 aagcaatggc agaacttaat aaaacaaaag taagaaaaga attgcggaca gagcgtccgt 1649341 ctatttattc ttttgaatta gatgaaatca aacaatggct gacagacaat ggagagaaac 1649401 cgttccgtgc agcccagatc tttgaatggc tatatgaaaa acgcgtatct tcttttgaag 1649461 atatgacaaa cctctcaaag gatctgcgtg agaaattaaa cactcgcttt gtgttaacaa 1649521 cgctgaaaac ggctgttaaa caaacctctc aagacggtac gatgaagttt ttgtttgagc 1649581 ttcatgacgg ttataccatc gaaaccgttt taatgagaca cgagtatggc aattctgtat 1649641 gtgtaacgac acaagtcggc tgccgtattg gctgcacatt ctgcgcgtca acgcttggag 1649701 gcttaaaacg aaaccttgaa gcaggggaaa ttgtcgctca agtagtcaaa gtgcaaaaag 1649761 ctcttgatga aacggatgaa cgcgtcagct ctgtcgtgat catgggaatc ggcgaacctt 1649821 ttgataactt taacgaaatg ctcgctttct tgaaaatcat taaccatgac aagggcctga 1649881 atatcggtgc tcgccatatt acggtctcta cgagtggaat catcccgaaa atttacgaat 1649941 ttgctgatca gcaaatgcag attaactttg caatttctct gcacgcgccg aacacagaaa 1650001 tcagaagccg tttgatgccg attaacagag catataaact gcctgatcta atggaagccg 1650061 ttaaatatta tattaataaa acaggacgcc gtatcagctt tgaatacggg ctgttcggag 1650121 gcgtaaacga ccaggtggaa cacgccgaag agcttgccga cttgctggaa ggagtcaaat 1650181 gccacgtgaa cttgattccg gtaaactacg tgcctgaacg ggactatgtg cgcacaccgc 1650241 gtgatcagat ttttgctttt gaaaaaacgc tgaaatcccg cggagtaaat gtcacaatcc 1650301 gaagagagca aggacatgac attgacgcag cctgcggtca gcttcgcgcg aaggagcgtc 1650361 aagacgagac gaggtgatga gggttgttaa cagccttaaa aacagataca ggaaaaatcc 1650421 gccagcataa tgaagatgat gcggggatat tcaaggggaa agatgaattt atattagcgg 1650481 ttgtcgctga tggcatgggc ggccatcttg ctggagatgt tgcgagcaag atggctgtga 1650541 aagccatggg ggagaaatgg aatgaagcag agacgattcc aactgcgccc tcggaatgtg 1650601 aaaaatggct cattgaacag attctatcgg taaacagcaa aatatacgat cacgctcaag 1650661 cccacgaaga atgccaaggc atggggacga cgattgtatg tgcacttttt acggggaaaa 1650721 cggtttctgt tgcccatatc ggagacagca gatgctattt gcttcaggac gatgatttcg 1650781 ttcaagtgac agaagaccat tcgcttgtaa atgaactggt tcgcactgga gagatttcca 1650841 gagaagacgc tgaacatcat ccgcgaaaaa atgtgttgac gaaggcgctt ggaacagacc 1650901 agttagtcag tattgacacc cgttcctttg atatagaacc cggagacaaa ctgcttctat 1650961 gttctgacgg actgacaaat aaagtggaag gcactgagtt aaaagacatc ctgcaaagcg 1651021 attcagctcc tcaggaaaaa gtaaacctgc ttgtggacaa agccaatcag aatggcggag 1651081 aagacaacat tacagcagtt ttgcttgagc ttgctttaca agttgaagag ggtgaagatc 1651141 agtgctaatc ggcaagcgga tcagcgggcg ttaccaaatt ctccgcgtca taggcggcgg 1651201 gggaatggcc aacgtgtatt tagctgagga tatcattcta gaccgtgaag tcgcaattaa 1651261 aatcctgcgg tttgactatg caaatgacaa tgaatttatc agacgtttcc gcagagaagc 1651321 ccaatccgca tcaagcctcg atcacccgaa tattgtcagc atttatgatt tgggcgagga 1651381 agatgatatt tattatattg tcatggaata cgttgaaggc atgacgctta aagaatacat 1651441 aacagcaaat gggccgcttc accctaaaga agcgctgaac atcatggagc aaattgtctc 1651501 agccatcgct catgcccatc aaaaccagat tgttcacaga gacatcaagc cgcataacat 1651561 tttgattgat catatgggaa atatcaaagt aacggatttt ggaattgcga cggcactaag 1651621 ttcgaccaca atcacccata ccaattcagt tctgggctcg gtccattact tatcacctga 1651681 acaggcccgg ggcggcttag ccacaaaaaa atcggatatt tatgcgcttg gaatcgttct 1651741 atttgagctt ttaaccggcc gtattccgtt tgatggagag tcagcagtca gcatcgcctt 1651801 gaagcatctt caagcggaaa ctccttcggc aaaaaggtgg aatccatcgg tcccccaaag 1651861 cgttgaaaac atcatactca aggcaactgc caaagatcct tttcatcgct acgaaacggc 1651921 tgaagacatg gaagcagaca taaaaacagc ttttgatgcc gacagactca atgaaaagag 1651981 atttacgatt caagaagatg aagaaatgac aaaagcgata cctatcatta aagatgaaga 1652041 acttgctaaa gctgctggcg aaaaagaagc tgaagtgaca accgcacaag aaaacaaaac 1652101 aaagaagaac ggcaaaagaa aaaagtggcc gtgggttttg ctcacgatat gcctcgtttt 1652161 tatcacagct ggaattcttg ctgtcactgt ttttccgtcg cttttcatgc ctaaggatgt 1652221 caaaatacct gatgtctccg gaatggaata cgaaaaagcc gcagggctct tggaaaaaga 1652281 aggtttacag gttgattccg aggtgttgga aatctcagat gaaaaaattg aagagggcct 1652341 gatggtaaaa acggatccta aagcggatac cacagtcaaa gaaggcgcca cggtcaccct 1652401 ttataagagc accggaaaag caaaaacgga gatcggtgat gtgacaggcc aaacggtcga 1652461 ccaagcaaaa aaagcgttga aggaccaagg gtttaatcat gtaacagtaa atgaagtgaa 1652521 tgacgagaaa aatgcgggca ctgtcattga ccaaaatcct tcagcaggga ctgagctggt 1652581 cccgagtgaa gatcaagtca aacttacagt cagtatcgga cccgaagaca ttacgcttag 1652641 agacttgaaa acctacagta aagaagcagc gtctggatat ctggaagaca acggattgaa 1652701 gcttgtagaa aaagaagcat actcagatga tgttccagaa ggacaggttg tcaaacaaaa 1652761 accagcagca ggtacggcag taaagccggg aaacgaagtt gaagtgacat tctctctcgg 1652821 accagagaaa aaacctgcga aaacagtgaa agaaaaggtc aagatcccct acgaaccaga 1652881 aaatgaaggg gacgagcttc aagtgcaaat cgcggttgac gatgcggatc acagcatctc 1652941 tgacacttac gaagaattta agataaaaga gccgactgaa cgaacgatcg aactaaagat 1653001 tgaaccaggc caaaaagggt actatcaagt aatggtaaac aataaagttg tcagctacaa 1653061 aaccattgag tatccgaaag atgaataaca aggagggaaa atatgcctga gggcaaaatt 1653121 attaaggcgc taagcggctt ttactatgta ctggatgaat cagaggattc agataaagta 1653181 atacaatgca gaggaagagg cattttcaga aaaaacaaaa ttacccctct tgtcggtgat 1653241 tacgttgtgt atcaagctga aaatgacaaa gaaggatatc taatggaaat taaagaaaga 1653301 accaacgagc ttatcaggcc gccaatttgc aacgttgatc aagcggtcct tgttttctca 1653361 gcggttcagc cttctttcag cacggcattg ctcgaccgct tcctggttct cgttgaggcc 1653421 aatgatattc agccgattat atgcattact aaaatggatc tgattgaaga tcaagataca 1653481 gaagatacga tacaagccta tgcagaagac tatcggaata ttggttatga cgtatacctt 1653541 acctcctcta aggaccaaga tagtttagcg gacatcatcc cgcattttca ggataaaaca 1653601 acggtatttg ccggtcagtc cggtgttggg aaatcctcgc ttctcaacgc gatcagtccg 1653661 gagctcggat taagaacaaa cgagatttcc gagcatttgg gccgcgggaa acacacaacc 1653721 cgccacgtgg agctgattca cacgtccgga ggtttggttg cagatacacc gggattcagc 1653781 tcgcttgaat ttacagacat tgaggaagaa gagctgggct ataccttccc tgatatcaga 1653841 gaaaaaagct cttcatgcaa atttagaggc tgtttacatc tgaaagagcc gaaatgtgcg 1653901 gtgaaacaag ctgttgaaga cggggaatta aagcagtatc gctatgacca ttatgttgaa 1653961 tttatgacgg agattaaaga cagaaagccg aggtattagc ataatgataa aggttgcacc 1654021 atctattctt tccgctgatt ttgccgcttt aggcaatgag attaaagatg tagaaaaagg 1654081 cggagccgat tgtattcata ttgatgttat ggacggccat tttgtcccga atatcacaat 1654141 cggtccgctg attgtagaag cggtccggcc ggtaacggat ctgccgcttg atgtccattt 1654201 aatgatagaa gagccggatc gttatatccc ggcttttgcg aaagcaggcg cagatatcct 1654261 gtctgtgcat gctgaggcat gtccgcacct gcaccgtacc atccagctca ttaaagagca 1654321 aggagtgaag gccggagtag ttctaaaccc gcatacccct gtacaagtca tcgaacatgt 1654381 tttcgacgat cttgatcttg ttcttttaat gacggtgaac ccgggcttcg gcgggcagaa 1654441 atttattcat tcagtccttc ctaaaataaa agaggttaag cgaatggcgg atgaaaaagg 1654501 aaaaaaagat ctgttaattg aagtagacgg cggcgtcaac aaagaaaccg ctccgctcgt 1654561 cattgaagcg ggcgcaaatt tactcgttgc cggttcagct gtttatggcc agtctgaccg 1654621 caaaaaagca atttctgaaa tcagaggaag taaataagca gctttagaaa agagctgggc 1654681 atacaatagc ctaagctctt tttcctgtat gcagagaaag gaatcagaga tgaaaacaat 1654741 taatatcgtt gcgggaggcc cgaaaaatct cattcccgat ctaaccggct atacggatga 1654801 acacacgctt tggatcggtg ttgacaaagg caccgtcact ctcttagatg ccgggatcat 1654861 tcctgttgaa gccttcggag attttgacag cataacggag caagaacgcc ggcgaataga 1654921 aaaagccgct cccgcccttc atgtgtatca agcagaaaaa gatcaaacag atttagacct 1654981 cgcccttgat tgggcgctgg aaaagcagcc ggatattatt cagattttcg gcattacagg 1655041 cggcagagct gatcattttt taggaaacat tcagcttctg tataaaggtg taaaaacgaa 1655101 cataaaaatt aggctgatag acaaacaaaa tcatattcaa atgttccctc ctggtgaata 1655161 tgatattgag aaggatgaaa ataagcgata tatctccttc ataccgtttt ccgaagacat 1655221 acatgagctg accctgaccg gttttaaata tcctctaaat aattgtcata ttacgctcgg 1655281 ttcaacacta tgtattagta acgaactcat tcattcacga ggtacttttt cgtttgcaaa 1655341 aggcatatta ataatgataa gaagcacgga ttaagcatgt gctttcattc aattgctgaa 1655401 aacaatgaac aaggcggtta cgggacgtta taggagggga caaaaatgaa attttacacc 1655461 attaaattgc cgaagttttt aggaggaatt gtccgggcga tgctgggctc atttagaaaa 1655521 gattaatgcc caggggttca aagccctctt tcaccacata aaaacgcctg ccacatatcg 1655581 gggcaggcgt tcattttgtt atacacgctc aactttaccg gatttcaaag ctcgagcaga 1655641 tacatatact tttttaggtt ttccgttcac aaggatacga accttttgaa gattcgcgcc 1655701 ccaagtgcgc ttagaagcgt tcattgcgtg agaacggtta ttcccagctg ttgttttttt 1655761 acctgtgata acgcatttac gtgccatttg tttccctcct cacttgcaca aaacatctac 1655821 tttttaacat tcatataatc ttagatgctt tcgatatgga tactttaaat aatttaccac 1655881 agctaaaaaa cgtttgcaac tattgtttca tcatctttca agaaaattca cttgacatct 1655941 tgcggaaaca gcagcgctat agtatatgta gaggtacggc cagcgattat tgcctggtct 1656001 tttcataatg gaaaccatat agtagaatag ctgtaactct atgcattcga aggaggaact 1656061 agtgtgtcca ttgaattaag aacgaagtac ggacagattg atatatctaa tgaagtcatc 1656121 gcgatggttg caggaggcgc ggcggttgac tgttacggca ttgtcggcat ggcctctaaa 1656181 aaccagatta aagacggact gactgaaatc cttcggaaag agaatttcag caggggtgtc 1656241 caagttcgcc aagaaggaga acagatacat atcgacatgt atatcattgt cagctacggc 1656301 acgaaaattt ctgaagtggc acataatgtc caaacaaaag taaagtacac agtaaatcaa 1656361 accatcggac tggcagtgga ttctgtcaat atttatgtcc aaggcgtacg agtgacgaac 1656421 ccgtagttag gaggagtagg attgtctatc agaacattag acggcagaac ctttgccgag 1656481 atgattcttg cgggagcgca gaatctgtct caaaacgcca gtgcagttga tgcactgaac 1656541 gtgttcccgg tgccggacgg tgatacggga acaaatatga acctgtcgat gacttccgga 1656601 gcaagagaag ttgaacaaat ggatacggat gatatcggga aggtgggctc cgcgttatct 1656661 aaagggctgc tcatgggagc acgcggaaat tcaggagtta tcctatccca attgttccgc 1656721 ggatttagca aaaacattga aacgaaaaaa gaaattaatg cacttgagtt tgccgctgcg 1656781 ctgcaagcag gtgtagacat ggcgtataaa gctgtcatga aacctgtaga gggcaccatt 1656841 ttaacagttg caaaagacgc tgcaaaaaaa gcaatgatct tagcagaaaa agaaaccgat 1656901 atcactgcgc tgatgactgc agtgacagaa gaagcagagg cgtctttaaa ccgcacccct 1656961 gaattgctac ctgtcctaaa ggaagtagga gttgtcgata gcgggggcaa aggcctgctc 1657021 tgtgtgtatg aaggtttcct tgcttcatta aaaggtgaaa ctgtacctca gaaagcagtt 1657081 cttccgtcac ttgacgacat ggtcagcgca gagcatcaca agagcgcgca aagcatgatg 1657141 aataccgaag atattgaatt tggattctgt accgaagtga tggttaggct tgatcagaca 1657201 aaaagagagt tcgacgaagg cacgttcagg caagacctca gccagttcgg agattctctg 1657261 cttgtgattg cggatgaatc gctggcgaag gttcatattc atgctgaaga gccgggaaac 1657321 gtgttaaact acgcccagca ttacggtgaa ttgatcaaaa taaaaataga aaatatgaga 1657381 gaacagcata cctctatcat cagtcaagaa agcaaacctg cagacaacga aacaccgccg 1657441 gcaaaacagc cgtatggcat tgtgactgta gcgatgggag aaggaattgc agacctattt 1657501 aaaagcattg gcgcttctgt tgtgattgaa ggcggccaga ccatgaaccc aagcactgag 1657561 gatattgttg atgccgtgaa gtctgtaaat gcagatacgg tatttatcct gcctaacaac 1657621 tccaacatta tcatggctgc taaccaagcg gccagcgtag tggatgaaca ggtttttgtc 1657681 attcctgcta aaacggttcc gcaagggatg tcagctctgc tggcttttaa cccggatcaa 1657741 gaagctgaag cgaacgaggc caatatgcta agcgccattc agcaagtaaa aagcggacag 1657801 gtgacgttct cagtcagaga tactcatatt gacggtaaag acattaaaaa aggcgacttt 1657861 atgggcattc tgaatggaac gattatcggc acttctgaaa atcagctgtc agccgcgaaa 1657921 atgctgctgt cagaaatgat cggagaagat gatgaaatcg tgaccattct atatggtgag 1657981 gatgcgtctc aggaagaagc tgagcagctt gaagcgtttc tcagtgaaaa gtacgaggag 1658041 attgaggttg agatccacaa tgggaaacag cctctgtatt cgtatatagt ttcagcagaa 1658101 tagaagggca atttgccctt ctattcttat gtctgctttt aagtgcggca gcgctgtaac 1658161 gcgcccgctt gccattttat atctgatcaa ttagtctaga agcaaagcgc taataagctc 1658221 tggttcataa ggaggaatag catgaaatac agaagcgttt ttgatattat cggcccggtt 1658281 atgatcggtc cgtccagctc tcatacagcg ggagctgcta gaatcgggag agtggccaga 1658341 agtttatttg gcagagagcc tgagcgcatc attgtatctt tttacggctc gtttgcggaa 1658401 acgtataagg gccacggcac agatgtcgcg attatcggcg gattgcttga ttttgataca 1658461 ttcgatgaac ggattaaaac cgctatacaa attgcagaag ctaaaggaat tgatatagag 1658521 tttcgggtag aagacgcagt cccggtccac ccgaacacag caaaaatcac catttctgat 1658581 gaaaagggtg agctggaact gacgggtatt tcgattggcg gaggaaagat tgaaatcaca 1658641 gaattgaatg gttttgagct ccggctgtca ggaaatcatc cggccatatt agttgttcat 1658701 aatgacaagt ttggcacaat tgccggtgtt gccaatgttc tggcgaaatt ttcaatcaac 1658761 gtaggacata tggaagtagc ccggaaagat atcggccagc ttgcgctgat gacaatagag 1658821 gtcgatcaaa atattgacga ccacattctc gacgagctgt cgaagctgcc gaatattatt 1658881 caagtgacaa agattgctga ctagcgaaaa gggtcaggag gagccagtta tgtttcgtaa 1658941 tgtaaaagaa ttaattgaga ttactaaaga aaaacaaata ttgatctctg atgtgatgat 1659001 agctcaagag atggaagtaa cagaaaaaac aaaagaggac atttttcagc agatggatca 1659061 taacctgtct gttatggaag cggcggttca gaaaggactc gagggagtta cgagccaaac 1659121 gggcttaaca ggcggagatg ccgttaaatt gcaggcctat attcgatcag gaaaaagcct 1659181 gtctggcccg ctgattttag atgctgtatc gaaagccgtt gcaacaaatg aagtaaatgc 1659241 agccatggga accatctgtg cgacaccgac tgcaggttct gccggtgtgg tgcccggtac 1659301 gttatttgct gtaaaagaaa agctgaatcc aacaagagaa caaatgatcc gctttttgtt 1659361 tacagccggg gctttcggat ttgtcgtggc caataacgca agcatttccg gcgccgccgg 1659421 aggatgtcag gcagaggttg gatcagcttc aggcatggcg gctgcggcta ttgttgaaat 1659481 ggcaggagga acacccgaac aaagcgcgga agccatggcc attacattaa aaaatatgct 1659541 aggcctcgtg tgcgaccctg ttgcagggct tgttgaggtg ccttgcgtga aacggaatgc 1659601 gatgggcgcg tcaaatgcga tgattgctgc tgatatggca ttggcgggca ttacaagccg 1659661 tattccatgt gatgaggtta tcgatgccat gtataaaata ggccaaacga tgccaactgc 1659721 acttagagaa acaggccagg gcggtttagc ggcaacaccg acaggaagag aattagagaa 1659781 aaaaattttc ggaggagcgc taggttcacg tgaaacaaca tcagcaaact agtatagcta 1659841 acattaaggg tattgggccg gaaacagaaa aaacattgaa tgaactcggt atttatgaca 1659901 tttctgatct tctgaattat ttcccttatc gctatgatga ctacgagctg agggatttag 1659961 aagaagtaaa gcatgatgaa agagtcacag tcgaagggaa ggttcattca gagccttctc 1660021 ttacctatta cggaaaaaaa cgaaacaggc tgacattcag gcttctggtc ggccactatt 1660081 taatcacagc cgtatgtttt aaccggcctt atttgaagaa gaagctttcg ctcggctctg 1660141 tggtgacggt ttcaggtaaa tgggacaagc accgccaaac catctctgtt caggagttga 1660201 aaaacgggcc gcatcaagaa gacaaaagca ttgaaccagt gtattctgtg aaagaaaatg 1660261 ttaccgtcaa aatgatgagg cgctttattc agcaggcgct gacccaatat gcagactcac 1660321 ttcctgatcc tcttccggaa aagctaagaa aaagctataa actgcctgac tattatcaag 1660381 cgttaaaagc aatgcaccag cctgaaacaa gggaagcatt aaagcttgcc agacggcggt 1660441 ttgtttatga agaatttttg ttgtttcagt tgaaaatgca ggcgttccga aaggcggaaa 1660501 gagagcagac acaagggata cggcagcgtt tttcaaacga agaactcatg agatttatca 1660561 aaagcctccc gtttcccctc acaaacgccc agtcacgcgt tcttcgcgaa ataacagcag 1660621 acatgtcttc tccatacaga atgaaccgtc ttcttcaagg ggacgttgga tcaggaaaaa 1660681 cggcagtcgc cgccattgca ctgtatgccg cgatcctatc cggataccaa ggagcgctca 1660741 tggtgccgac agaaattctg gccgagcagc atgctgattc gctcgtttcg ctatttgaaa 1660801 aatgggacgt cagcgttgct cttttgacaa gctctgttaa aggaaagcgg cgaaaagaac 1660861 tgcttgagcg tcttgcggcg ggtgagattg atattcttgt aggaacccat gctttaatcc 1660921 aagacgaggt ggagtttaag gcgttgagtc tcgttattac tgatgaacag cacagatttg 1660981 gagttgagca gcgcaaaaag cttcggaaca aagggcagga tcccgatgtt ctctttatga 1661041 cagccactcc aatcccaaga acattagcga tcacagtatt cggtgaaatg gatgtatctg 1661101 tcattgatga gatgccggct ggacgaaagc gaattgaaac ctattgggta aaacatgaca 1661161 tgcttgatcg tattttggca tttgtcgaaa aagaattaaa gcaaggcagg caggcttata 1661221 tcatctgtcc gctgattgaa gaatcagata agcttgatgt gcaaaacgcc attgacgtgt 1661281 acaatatgct ttctgatatt tttcggggaa aatggaatgt cggccttatg catggaaagc 1661341 tgcattccga tgaaaaagat caggtcatga gagaattcag cgcaaatcac tgtcaaattc 1661401 tcgtatcaac cactgttgtg gaggttggcg taaatgttcc gaatgcaaca attatggtga 1661461 tttatgacgc cgaccgtttc ggactatcac agcttcacca gctgcgcggc cgtgttggac 1661521 ggggtgagca tcaatctttc tgtattctga tggctgatcc aaaatcagaa acagggaaag 1661581 aacggatgag gatcatgtcg gagaccaatg acggtttcga gctgtctgaa aaggatctgg 1661641 aactgagagg tcccggtgat ttcttcggga aaaaacaaag cggaatgccg gaatttaaag 1661701 tggcggacat ggttcatgat tacagagcgc ttgaaacggc aaggcaggat gctgcgaatc 1661761 ttgtggcttc tgacgcgttc tggaaggagc cggaatacgc tgtgttaaga gatgaattgc 1661821 tgaagagcgg agtaatggac ggggaaaaat taagctgagt atcagaagtt tttggtgttc 1661881 agccagaaac aatcgttgca ttccaatcta tgaaattata tactactatt agtacctagt 1661941 cttaattgtc cggatggtgt ttagatatga gaagaaataa gagagaacgc caggaattac 1662001 ttcagcagac gattcaagca acccccttta ttacagatga agaactagcg ggtaaattcg 1662061 gggtgagcat ccagacgata cgtttggacc gcttagagct ttccatacct gaactgagag 1662121 aaagaattaa gaacgtggca gagaaaacac ttgaggacga agtgaagtcc ctgtcacttg 1662181 atgaagttat cggagaaatt attgaccttg agctggatga tcaggcgata tccattttag 1662241 aaataaaaca ggagcacgtg ttcagccgga atcagattgc gagaggacac catttatttg 1662301 cacaggcgaa ttctttggcc gttgcagtca ttgatgacga gctggcgctg actgcaagtg 1662361 cagacatccg ctttacaaga caggtaaagc agggtgaacg tgtcgtagca aaagcgaaag 1662421 tgacggctgt cgaaaaagaa aaaggaagaa cggttgtcga agtgaacagc tacgttggcg 1662481 aagaaattgt tttttctgga cgctttgaca tgtatcgttc aaaacattca taaaggtgga 1662541 gcatgcatga gaatagctgt agatgcaatg ggaggagacc acgctcccaa agctgttatt 1662601 gacggagtta taaaaggtat agaggcattt gatgatctcc atatcacact tgtcggtgac 1662661 aaaacaacga tagaatcaca tttaacaact acatcagatc gcatcacggt gctgcacgca 1662721 gatgaagtga ttgagcctac ggatgaaccg gtccgtgccg tgcgaagaaa aaagaactca 1662781 tctatggttc ttatggcgca ggaggttgcg gaaaacagag ctgacgcctg catttcagcg 1662841 ggaaataccg gtgcattaat gacagccggt ctctttattg tcgggagaat taaaggaatt 1662901 gaccgtccgg cgcttgctcc gacacttccg actgtttcgg gagacggatt tcttctcctt 1662961 gatgtcggcg ccaatgtcga tgccaaaccg gagcacctcg ttcaatatgc catcatgggt 1663021 tctgtttatt ctcagcaagt gcgcggtgtc acttcaccga gagtcggact tttaaatgtc 1663081 ggaacagaag ataaaaaagg aaacgaactg acgaagcaga cgtttcaaat tttaaaagaa 1663141 acagcaaaca tcaattttat cggaaacgtg gaagcgcgag accttttaga tgatgtggcg 1663201 gatgttgtag taacagacgg ctttaccggg aatgttacac tcaaaacgct ggaaggctct 1663261 gcgttgtcaa tttttaaaat gatgagagac gtaatgacgt ctactttgac atccaagctt 1663321 gcagcagctg tgctgaaacc aaaattgaaa gaaatgaaaa tgaaaatgga gtattcgaat 1663381 tatggcggag caagtctttt tggcttaaaa gcgcctgtga tcaaggcgca cggctcttca 1663441 gattcaaatg ctgtattcca tgcgattcgg caagcaagag agatggtcag ccaaaatgtg 1663501 gctgcgctca ttcaggaaga agtgaaagaa gaaaaaacag atgagtagtc tggaggtttt 1663561 tacatcatga gtaagattgc atttttattc ccgggtcagg gatcacaatt tatcggcatg 1663621 ggaaaagagc tttatgagca ggtgcctgct gcaaagcgtc tgtttgatga agccgatgaa 1663681 acgttggaaa caaaactcag ctcgcttatt tttgaggggg atgctgaaga attaacactt 1663741 acatacaatg cgcagcctgc tttgcttacg acaagcatcg ctgttcttga gaaatttaaa 1663801 gaatctggca ttacacctga tttcacagca ggacacagcc ttggtgaata ttctgcactg 1663861 gttgcggctg gcgctctgtc tttcaaagat gctgtttata ctgtcagaaa gcgcggagag 1663921 tttatgaatg aagcggtgcc ggctggcgaa ggagcaatgg ctgcgattct cggcatggat 1663981 gctgaagcat taaagcaagt aaccgataaa gtcacagagg aaggcaacct tgtacagctt 1664041 gcgaatctca actgtcctgg ccaaatcgtc atttccggaa cagctaaagg ggttgagctt 1664101 gcatctgaac tggcaaaaga gaacggcgca aaacgcgcaa ttccgcttga agtaagcggt 1664161 ccgttccatt ctgaactgat gaaaccggct gctgaaaagc tgaaagaggt attggacgcc 1664221 tgtgacataa aagacgctga cgttccggtc atctcaaatg tttctgctga cgtgatgact 1664281 gaaaaagcag atatcaaaga aaaacttatt gagcagcttt actctccggt tcgttttgag 1664341 gaaagcatta acaagctgat cgcagagggt gttacgactt ttattgaaat cggtcccgga 1664401 aaagtgcttt caggccttgt gaaaaaagtg aatagacggt taaaaacaat tgctgtatca 1664461 gatccggaaa cgatcgagct ggcaattcaa acgcttaagg aggagaatga taatgcttaa 1664521 tgataaaacg gctattgtca ctggcgcatc ccgcggaatc ggccgctcaa tcgcccttga 1664581 tctggcaaaa agcggagcaa atgttgtcgt gaactactcc ggcaatgaag cgaaagcaaa 1664641 tgaagtggta gatgaaatca aatcaatggg cagaaaagca attgctgtaa aagcggatgt 1664701 atcaaatccc gaagatgtac aaaacatgat aaaagaaaca ttgtctgttt tttctacgat 1664761 tgacattctg gttaataatg cgggaattac aagagacaat ctcatcatga gaatgaaaga 1664821 agacgaatgg gatgacgtca ttaacattaa cctgaagggt gttttcaact gcacaaaagc 1664881 tgttacaaga caaatgatga aacagcgttc aggccgcatt attaacgtat cgtctatcgt 1664941 cggcgtcagc ggaaaccctg gacaagccaa ctacgtggct gcaaaagccg gcgtcatcgg 1665001 tttaaccaaa tcttctgcta aagagctcgc cagccgaaat attacggtaa acgcaatagc 1665061 gccaggattt atctcaactg atatgacaga taaacttgca aaagacgttc aagacgaaat 1665121 gctgaaacaa attccgctcg cgcgctttgg tgaacctagc gatgtcagca gtgttgtcac 1665181 gttcctagct tcagagggag ctcgttatat gacaggccaa acgcttcata ttgacggcgg 1665241 aatggtgatg taagtttttt ctcgaaaatt tcatcgtagt ttctctagtt ttttaaaaac 1665301 gaatccacta taatacttga ggggaggtga attgctatgg cagacacatt agagcgtgta 1665361 acgaaaatca tcgtagatcg ccttggcgtt gatgaagcag acgtcaaact tgaagcttct 1665421 ttcaaggaag acttaggtgc tgattcccta gatgtagttg agcttgttat ggaacttgaa 1665481 gacgagtttg atatggagat ttctgacgaa gatgctgaaa agattgcaac agtcggcgac 1665541 gctgtgaact acatacaaaa ccagcaataa gctgatgcta aaagtcccgc cgaaacgcgg 1665601 ggctttagcc ctttattcgt gcagttatta cagcatgccg cttttacgcg cgctgtatcc 1665661 ggtttagtca gagaagcgcg gtgaacctga tgtgcctatg gaggttacta tgtcaaaaca 1665721 ctcacattat aaagataaaa aaaagttcta taaaaaagta gaacaattta aagagtttca 1665781 agaacggatt tcggttcact ttcaaaatga aaagcttttg tatcaagcat ttacacattc 1665841 atcttatgtg aatgagcatc ggaaaaagcc gtatgaagat aatgaaaggc ttgaattttt 1665901 aggtgacgct gttttggaac tgacgatctc cagattctta tttgccaaat acccggctat 1665961 gagtgaagga gatttgacga aattgagagc cgcaattgtt tgcgaaccgt ctctcgtttc 1666021 attggctcac gagctgtcat tcggcgatct tgtcctgttg ggtaaaggcg aggaaatgac 1666081 aggcggaaga aagcgtcctg ctctattggc ggatgttttt gaggcattta tcggagcctt 1666141 gtaccttgac caaggattag agccggtcga aagtttctta aaagtttatg tgttccctaa 1666201 aattaacgat ggtgcttttt ctcatgtgat ggatttcaaa agccagctgc aggaatacgt 1666261 gcagcgggac ggcaaaggct ctctggagta taaaatctcc aacgaaaaag gacctgcgca 1666321 caaccgtgaa tttgaagcca tcgtatctct aaaaggtgaa ccactcggag tcggaaacgg 1666381 ccgttcaaag aaagaagccg aacagcacgc tgctcaggaa gctttagcta aattgcaaaa 1666441 acaccatacg aaacaataaa atccccctta tgactcaggg ggatttcagt atgtatgccg 1666501 tcttatttga ccaatgttta tgatagaatt gaaatactta ttacataagg aggatcgcta 1666561 tgttcctcaa acgtttagac gttataggat ttaaatcatt tgcagaacgg atttccgtag 1666621 acttcgttaa aggcgtgaca gcagttgtcg ggccgaacgg aagcggaaaa agcaacatca 1666681 cggatgccat tcgctgggtt ctcggcgaac aatcggcacg ctctcttcgc ggcggaaaaa 1666741 tggaagacat catttttgct gggagtgatt caagaaagcg attaaatcta gctgaagtta 1666801 cgcttactct tgataatgat gatcatttct tgccaattga cttccacgag gtgagtgtca 1666861 caagacgtgt gtacagatca ggtgagagtg agtttctgat taacaatcag ccatgccgct 1666921 tgaaagatat tattgattta tttatggact ctgggcttgg taaagaagca ttttctatta 1666981 tcagccaagg gaaagtggaa gagatcctga gcagcaaagc ggaggatcgc cgcagtatct 1667041 ttgaagaagc ggccggggtg cttaaatata aaacgagaaa gaaaaaagca gaaaataaac 1667101 tgtttgagac acaggacaat ctaaatcggg tagaagatat attacatgag cttgaaggac 1667161 aggttgaacc tcttaaaatt caagcttcaa tagcgaaaga ctaccttgag aaaaagaaag 1667221 agctggagca tgttgaaatt gcgctgactg cctatgatat cgaagagctg catggtaaat 1667281 ggtcgactct taaagagaaa gtgcagatgg caaaagaaga agagcttgct gaatcgtctg 1667341 ctatttctgc gaaagaagca aagattgagg atacaaggga caaaatacaa gcgcttgatg 1667401 agtcagtaga tgagctccag caagttttac tggtaactag tgaagagctg gaaaagcttg 1667461 aaggccgtaa agaagtcctg aaagaacgaa agaaaaacgc tgtgcaaaac caagaacagc 1667521 ttgaagaagc catcgttcag ttccagcaaa aagaaacggt tctgaaagaa gagctttcga 1667581 agcaggaagc tgtcttcgaa acgcttcagg ctgaggtgaa gcagttaagg gcgcaagtaa 1667641 aagaaaaaca gcaggctctc agtcttcaca atgaaaatgt cgaagagaaa atcgagcagc 1667701 tgaaaagtga ttattttgag ctgttaaaca gccaggcttc gatacgcaac gaactccagc 1667761 ttcttgatga ccagatgtcc caatccgctg tcacattgca gagacttgcg gacaacaatg 1667821 aaaagcacct gcaggaacgg catgatattt ctgcgcgtaa agccgcatgt gaaacggaat 1667881 ttgcccgaat tgagcaggag attcacagtc aagtcggtgc atatcgtgat atgcagacaa 1667941 aatatgagca gaaaaagcgc caatacgaaa aaaatgaatc cgctctgtat caggcatacc 1668001 aatacgttca gcaagcgaga tcaaaaaagg acatgcttga gacgatgcag ggagatttct 1668061 ccggctttta tcaaggtgtt aaagaagtgc tgaaagcgaa agagcgcctt ggcggaattc 1668121 gcggagcggt tcttgagctg atttctacag aacagaagta tgaaacggcc attgaaatag 1668181 cgctcggcgc ttctgctcaa cacgtcgtga ccgacgatga acaatctgcc cgcaaagcga 1668241 ttcaatattt aaagcagaat tccttcggcc gggcgacgtt tctgcctctt tctgttatta 1668301 gagaccgcca gcttcaaagc cgtgacgcgg aaacagccgc ccggcattca tcatttctcg 1668361 gggttgccag tgaacttgtc acatttgatc ctgcgtatcg aagcgtcatc cagaatcttc 1668421 ttggaaccgt tctgatcaca gaggacttaa agggtgcaaa cgagcttgcg aagcttctcg 1668481 ggcaccggta ccgcatcgta acccttgagg gagatgttgt gaaccccggt ggttcaatga 1668541 cgggcggcgc ggttaaaaag aaaaataact ccctccttgg aagaagccgg gagctagaag 1668601 atgtgacgaa acggctcgct gaaatggaag agaaaacggc actgcttgaa caagaggtca 1668661 aaacccttaa gcactccatt caggatatgg agaaaaaact ggctgactta agagaaaccg 1668721 gggaaggctt aaggttaaag cagcaggatg tgaaaggcca gctgtacgaa cttcaagttg 1668781 ccgagaaaaa tatcaatacc catttagagc tctatgatca agaaaaatct gctctgtcag 1668841 aaagcgatga agagagaaaa gtgcgcaaac gcaagcttga agaagagctc tctgccgtat 1668901 ctgaaaagat gaaacagctt gaagaggaca tagacagact gacaaaacaa aaacaaacgc 1668961 aatcctcaac gaaagagtct ctctccaacg agctgactga gctgaagatc gcagcggcca 1669021 aaaaagagca ggcttgcaag ggggaagagg acaaccttgc cagattaaag aaagagctca 1669081 ctgaaacaga gcttgcgtta aaagaagcaa aagaagactt aagcttctta acgtcagaga 1669141 tgtcatctag caccagcggc gaagaaaagc tggaagaagc agcaaaacat aaattgaatg 1669201 acaaaacgaa aacgatcgaa ctgattgcat taaggcgcga tcagcgcatc aagcttcagc 1669261 atgggcttga tacgtatgag cgtgagctga aagaaatgaa acgcctgtat aaacaaaaaa 1669321 caacgctctt aaaagacgaa gaagtcaaac ttggacgaat ggaagtcgag cttgataatt 1669381 tactccaata cttacgggag gaatacagct tgtcctttga gggggcaaaa gagaaatatc 1669441 agcttgaaac tgatccagag gaagccagaa agcgcgtgaa gctgattaaa ctcgcaattg 1669501 aagagctggg taccgtgaac ctcggaagca tagatgagtt tgagagggtc aacgaacggt 1669561 acaagtttct gtcggaacaa aaagaagatt taacagaagc gaaaaatacc ttgttccaag 1669621 tgattgaaga aatggatgaa gaaatgacga agcgctttaa cgacacattc gtccaaatcc 1669681 gctcacactt tgatcaagtt ttccgctcct tattcggagg agggcgagct gaactgaggc 1669741 tcaccgatcc taacgatctg cttcattcag gagtcgagat tatcgctcag ccgccgggga 1669801 aaaagctgca aaacttaaac ctcctgtcag gcggagagcg tgcgcttact gctatagcgc 1669861 tcttattctc aatcctaaag gttcgtccag tgccgttttg cgtccttgac gaagtagagg 1669921 ctgcgctcga cgaagcgaat gtgttccgat ttgcgcagta tttaaaaaaa tacagcagcg 1669981 atactcagtt tattgtgatt acccacagaa aaggaacgat ggaggaagcg gatgtgcttt 1670041 atggcgtaac catgcaggaa tccggtgttt ccaaggtaat ttcagttaag ctggaagaaa 1670101 caaaagaatt cgttcagtaa cgaggaaaga ggttaaaaga tgagcttttt taaaaaatta 1670161 aaagagaaaa tcacaaaaca gacagattcc gtatctgaaa agtttaagga tggccttgaa 1670221 aaaacaagaa actcctttca aaacaaagtg aatgatcttg tatcccgtta ccgtaaagtg 1670281 gatgaggatt tcttcgaaga gcttgaagag gttcttatca gcgcggatgt cggttttaca 1670341 accgttatgg aattaataga tgagctgaaa aaagaagtca aacgcagaaa tattcaagat 1670401 ccaaaggaag tccagtcagt gatttctgag aaactggtcg agatttataa cagcggagat 1670461 gagcaaattt cagaactgaa catccaggat gggcgtttaa acgtaatcct tctggtaggt 1670521 gtaaacggcg tcgggaaaac aacaacgatc ggaaagcttg ctcataaaat gaaacaagaa 1670581 ggaaaatctg ttgtacttgc cgccggagac acttttagag cgggagccat tgaacagctg 1670641 gaagtatggg gagagcgtac aggagtgcct gtcattaagc agacggcagg aagcgatccg 1670701 gcggctgtca tctacgatgc tgttcatgct gcgaaagcaa gaaatgccga tgtattaatt 1670761 tgtgatacgg cagggcgtct ccaaaacaaa gtaaatctca tgaaagagct tgaaaaagta 1670821 aaacgtgtta tcgaaagaga agttcctgaa gctccgcatg aggtgctgct tgcccttgat 1670881 gccacgaccg gccaaaatgc aatggctcag gcaaaagaat tctctaaagc aacaaatgtt 1670941 accggcattg ctttaacgaa gcttgacggt acggcaaaag gcggtatcgt ccttgcgatt 1671001 cgcaacgagc ttcacatccc ggttaaacta gtcggtttag gagaaaaagt tgatgacctt 1671061 caggaatttg atccagaatc ctatgtgtac ggactctttt cagatttagt ggaaaaagcc 1671121 gacgattaag aaaaaggccc caacatcttg gggccttttt cttttttatc ttcttacttg 1671181 ataggcgaaa tgataaaggc tgttatcagt ggataccagt cttgactcac cagaaaaaac 1671241 tctgaatggg atgatgtcat agtaatgaac ggaaacagat gtgtaatacg tatagtaacc 1671301 agcagctggc cccaaataca ttggaacctc aaatgttccg tttgcatcag tcgttcctga 1671361 agcagtttgt gttgtgtttc cgaccttcgt gtccgcttca aatcttacgg gcgcgtttgg 1671421 cactggctgt ccgttttggt cgagtaattt gccgcttact gtaatattgt acttgactcg 1671481 ccaatattga ccttgtccgt aattgatttt accgtatacc cctccatctg tgctgatatt 1671541 tgtgattgag gccttataag gtgcctcagc agcgtctgct tgctgtgccg ggaaacctat 1671601 tgtaaacagg gctgccagac ataacataaa caataaaccg atttttttca taaaaatcct 1671661 ccttaaaata gggttcatat acaatatcgg aataaattgg atgatattta gcgtattttg 1671721 gaaaagttaa tcgccgcttt gacaagataa aaacttgaca gtgtcattaa aaccgtgtaa 1671781 actaagttat cgtaaaggga tttgacttaa caaaggggag agctcaaatg tcactcgaaa 1671841 agacaacgag aatgaattat ctgtttgatt tttatcagtc gttgttgacg tcaaaacaga 1671901 agagctatat gtcgctttat tatttggacg atttctccct aggcgaaata gccgaagaat 1671961 atgaggtttc aagacaagct gtttatgata acatcaaacg aacagaagca atgcttgaac 1672021 aatatgaaga aaagctgctc cttttgaaaa agtttcagga gcgtaaagag atgtttaata 1672081 agctgaagga gcttgcttcc ggttcaaaag aagaggaaga aattacagct ctgattgaag 1672141 cgcttgagaa attagattag gaggcggcaa actatggcat ttgaaggatt agccgaccga 1672201 ctgcagcaga cgatttctaa aatccgcgga aaagggaaag tcagcgaaca agatgtaaaa 1672261 gagatgatgc gtgaggtccg tcttgcgctg cttgaggctg acgttaactt taaagtagtc 1672321 aaggattttg tcaaaaaagt aagtgaacgc gctgtaggcc aagacgtcat gaaaagtctg 1672381 acgcccggcc agcaggtcat taaagttgtt caagaggaac tgactgagct gatgggcggc 1672441 gaagagagca aaatcgccgt cgcaaaaagg ccgccgactg ttattatgat ggtcggtctc 1672501 caaggtgccg gtaaaacgac aacaagcggt aagcttgcga atctgctgcg caaaaagcat 1672561 aatcgcaaac cgatgctggt tgctgccgat atttaccgcc cagccgcaat taagcagctg 1672621 gaaacactcg gcaaacagct tgatatgcct gttttctctc ttggcgatca ggtcagtcct 1672681 gtagaaatag ctaaacaggc tattgagaaa gccaaggaag aacattatga ctacgtcatt 1672741 ttggatacgg cagggcgctt gcatatcgac catgaactga tggatgaact gaccaacgtc 1672801 aaagaaatcg cgaatccgga agaaattttc ctggttgtcg attcaatgac cggtcaggac 1672861 gctgtgaatg ttgccaaaag ctttaatgaa cagctcggtt taaccggtgt tgtgttgact 1672921 aagctggatg gagacacacg cggcggggct gcgctttcta ttcgcgctgt cacaaacacg 1672981 ccaattaagt ttgcaggttt gggcgaaaag cttgatgcgt tagagccgtt ccatcctgaa 1673041 cgcatggcat caaggattct cggcatgggc gacgtgctga cattgattga aaaagcacag 1673101 gccagcgttg atgaagacaa agccaaagag ctggaacaaa aaatgagaac gatgagcttc 1673161 acattggacg attttctgga gcagctcggg caagtcagaa acatggggcc gcttgatgag 1673221 cttctgcaaa tgatgccggg tgcaggtaaa atgaagggcc tgaaaaacat ccaagttgat 1673281 gaaaaacagc tgaatcatgt ggaagcaatc atcaaatcaa tgactgttct tgaaaaagaa 1673341 cagccggata ttatcaatgc cagccggcgg aagcggattg caaaaggaag cgggacatcc 1673401 gtacaggaag tcaaccgtct gcttaagcag tttgatgaaa tgaaaaaaat gatgaagcag 1673461 atgacaaaca tgtcaaaagg caagaaaaaa gggtttaagc taccttttat gtaatcggtt 1673521 atacatgata aaaccgttgt taagaaaaaa cactttacaa acacttttat cattgttaat 1673581 atactatctt gttgaaatat tttcggaggt gctagtaaaa tggcagtaaa aattcgttta 1673641 aaacgtatgg gagcaaaaaa atctcctttc tatcgtattg ttgtagcaga ttctcgttca 1673701 ccacgtgacg gccgtttcat cgaaacagtc ggaacttaca acccggttgc aaaaccagcg 1673761 gaagtaaaaa ttgacgaaga gcttgctctt aaatggcttc aaactggagc gaaaccatct 1673821 gatacagttc gcaacttgtt ctctagccaa ggaatcatgg aaaaattcca caacgctaaa 1673881 caaggcaagt aatgactgat caacacttgg aagatttgat tgtccacatt gtgacgccgc 1673941 ttgttgatca tccagatgac attcgcgtca taagagaaga aaccgatcaa aagattgcgc 1674001 tgcgcttatc tgtccataag tcagataccg gtaaagttat cggaaagcaa ggccggactg 1674061 caaaagcgat tcgaacagct gtatttgcag ctggcgtaca gtcttctaag aaagttcaat 1674121 ttgaaatatt tgactaaaag ggagagggcc ggcacctccc ctttttttac acgcaaaaaa 1674181 agggtaaact gatagaagct taggcaaaat agaaaagcct ggacgagtaa aagttttaaa 1674241 agcggggagc ttggtgcgat gcaaattatt caccgtgtag ccgttatgca agtcttaacc 1674301 gagcgcagta aagaaaagct tttagcttct tttgctgaga agaaacaaat gcttgaacga 1674361 gaatgcagcc agctctattt tcagcttaga aaacatgaga aagaacagca aaaccctaat 1674421 atgattgaac aatttaaaaa ggcaatagaa aagcgaaaag atgatataaa aatcattgat 1674481 tttcaaattg ctcaagtaca tacattgccg cttggcagtg agttgaaaga aaaggaagtc 1674541 gatgcgctgc tgacgattga agccggggat gactggcatg agaaaacagc agcgaacacc 1674601 atcgtcataa aagacggaaa agtaattgaa attcgccaga ggtgatcata tgacaaagcg 1674661 atggtttaat gtaggcaaaa tcgtaaatac ccacggaatc aaaggcgaag tgcgggtgat 1674721 ttcaaaaaca gattttgccg aagaacgata caagccggga aacacgctgt atttgtttat 1674781 ggacggccgt aacgaaccag tggaggtaac ggtaaacaca catagactgc ataagcaatt 1674841 tcatctcctg cagtttaaag aaagacaaaa cctaaatgaa gtagaagagc tgaaaaacgc 1674901 aatcattaaa gttcctgaag aagaattagg agagctgaat gagggtgaat tttatttcca 1674961 cgaaattatt gggtgtgaag tatttactga agaaggcgaa ctcatcggaa aggtcaaaga 1675021 aattttgacg cctggagcca atgacgtttg ggtcatcgga cgaaaaggaa aaaaagacgc 1675081 actcattcct tacattgaat cagtggttaa acatatcgat gtcagggaaa agaaaattga 1675141 gattgaactc atggaagggt taatagacga atgaaaatcg attttttgac gctgtttccc 1675201 gaaatgtttg aaggcgtgct cggctcatcg attcttcaaa aagcccagga aaaagatgcg 1675261 gtgcagtttc aagtcgtaaa tttccgagag tactctgata acaagcacaa tactgttgat 1675321 gattatcctt atggcggcgg ggcaggcatg gttctcaagc cccagcctgt ttttgacgcg 1675381 gtcgaggacc tgacatcaaa ggcagccgct gctccgcgta ttatcctcgt atgcccgcaa 1675441 ggtgagcgtt ttacccaaaa aaaagccgaa caattagcta aggaagagca tttgctgttc 1675501 atttgcggcc actatgaagg ctatgatgaa cgcattcgcg agcacttggt aacggatgaa 1675561 atatcaattg gcgactttgt tctgacgggc ggtgagctcc ctgcaatgat gatcgcagac 1675621 agtgtggtca gactgcttcc gggtgtactg ggtaaagagg cttcccatat tgaggattcc 1675681 ttcagcaccg gacttttaga gcacccgcat tatacaagac cggcagatta caaaggttta 1675741 aaagtgcctg aaacactctt gtcaggaaac catgcaaaaa ttgaagaatg gcggaataaa 1675801 gaatcgatca gaaggaccta cctaagacgt ccggatctgt tgaaagacca cccgcttaca 1675861 gagcagcaaa gaaagtggat ttctgaatgg gaaaaagaat agattttatt gcataggcta 1675921 tgaaattgtg ataagatact acttgtggct taagcgggct tatccgctgc aagcttgaaa 1675981 acgatgttcc gctgtgccgg tttttgtggc caagagcatc tgttggaagg agttgaaaac 1676041 gatgcaaaaa ctaattgaag atatcacaaa agaacagctt cgtactgatc ttcctgcgtt 1676101 ccgtcctggt gacactttac gtgtacacgt taaagttgtt gagggtaacc gtgagcgtat 1676161 ccagatcttt gaaggtgttg tgattaagcg tcgtggtggt ggaatcagcg aaacgttcac 1676221 agttcgtaag atttcttacg gtgttggcgt tgaacgtact ttcccagtac acacaccaaa 1676281 aatcgcgaaa atcgaagttg tacgttacgg taaagtacgc cgtgctaaac tttactacct 1676341 gcgtgaactt cgcggaaaag cggctcgtat taaagagatc agacgataat gataacgaac 1676401 gaaaagagct tgttacctgt aacaagctct ttttttatac agaatttgaa aatgccggac 1676461 aggcatcgta aaatacataa aggacaacaa tgaatcatgc atactgaaga taaaggcggt 1676521 gttcgtgtca catgacaatt caatggttcc cgggccatat ggcaaaagca agaagggaag 1676581 taaccgaaaa attaaaatta atcgatatcg tatatgaatt ggtagatgcc agaattccaa 1676641 tgtcatcaag aaacccaatg attgaagata ttctaaaaaa caagccgcga attatgctgt 1676701 taaacaaggc tgacaaagca gatgcggcag ttacacagca gtggaaagag cactttgaga 1676761 accaggggat ccgctctctg tctattaatt ctgtaaatgg acaagggtta aatcaaattg 1676821 tgcctgcatc aaaagagatc ctccaagaaa aatttgaccg gatgcgtgcg aaaggtgtga 1676881 agccgagagc gattcgcgct ttgattatcg gcattccaaa cgtcggaaaa tcaacgctca 1676941 tcaaccggct tgcaaagaaa aacatagcaa aaacgggaga cagacctggt attacgactt 1677001 ctcaacagtg ggtcaaagtt gggaaagaat tagagctatt agatacaccg ggaattttgt 1677061 ggcctaaatt tgaggatgag cttgtcggtt tgagactggc agtcaccggg gctattaaag 1677121 actcgattat caatttgcag gacgtggccg tgtttggtct tcgttttctc gaagaacatt 1677181 acccagaacg gcttaaagag cgttatggcc ttgatgagat cccagaggac attgccgagc 1677241 tgtttgatgc aataggtgaa aagcggggct gtctcatgag cggtgggctc atcaactacg 1677301 ataagacgac tgaagtcatc attcgcgata ttcgcactga aaagttcggc aggctgtcat 1677361 ttgaacagcc gacgatgtaa aggcgcgcag aaatgcgggt ctttattttt tcttggctga 1677421 accgatacat acagtaaggg agaagagaaa gtgaatacat taaccgtaaa ggacattaaa 1677481 gaccgtttgc aggaagtgaa ggatgcacaa gacccattta ttgcccaatg cgaaaacgac 1677541 ccgagaaaaa gcgttcaaac gcttgtagag caatggctta aaaagcaagc gaaagaaaaa 1677601 gcgctgaaag aacaatgggt gaatatgact tcctatgaaa ggctggcaag aaacaaagga 1677661 tttcgcttga ttgcaggtgt tgacgaggtc ggccgggggc cattggcagg accagttgtc 1677721 gccagcgcag tcatccttcc agaggaatgt gaaatacttg ggctgacaga ctccaaaaag 1677781 ctttcagaga aaaaacgcga ggaatattac gagcttatta tgaaggaagc actggcggtc 1677841 gggataggaa ttgtagaagc tactgtgatt gatgagatca atatatatga agcttcaaaa 1677901 atggcaatgg tgaaagcgat acaggatttg tcggatacac ctgattattt gcttgttgac 1677961 gcaatgacac ttccgctcga cacggctcag gcgtcaatta taaaaggcga tgccaaaagc 1678021 gtgtctattg cggcaggtgc gtgtatcgca aaagtgacga gggaccgaat gatgagcgct 1678081 tatgccgaaa cgtatcccat gtacggcttt gaaaaaaata aaggctatgg gacaaaagaa 1678141 catttggaag ctctcgctgc atacggccca actgaattgc accgcaaaac tttcgctcct 1678201 gttcaatctt tcagataaat caccatggac aaggaggcac ctttttaaaa tgaacatacg 1678261 aaatgatgtg caaaaggcgc tgcagcacct tttcgggcgt acagccgtcc cgcaggaaac 1678321 atcaaaagta aacgaagcgc taaacgggga gaagcgtctc ctcttaggaa aagtgcttcg 1678381 tttactagga gatcagcatg ccctgatcca agtcggcaat caaactgttc agggaaaact 1678441 tgaaactcag cttcgtcctc aggcatacta ttggttttcc tacgaaaaaa aaacggcaga 1678501 gcaaacaggc cgtcttcagg tcgttcaaag ctttgatcaa aatcctaaaa ccattcagga 1678561 tgcagctggc aaacttttaa atgctatttc agtgaagacg tcaaacgcag ctctcatgat 1678621 gacaggagcg atgctgaaaa gcaaaacacc cgtaacagaa aatgatatca aaacagctgt 1678681 ccgctggatg gacacgctgc cttcgcaaga cacaaaaaaa gcagttgaaa cggttctctt 1678741 cgctttaaag cgtgatcttc ccattcactc cgagattttg aatggtgttc acgctgtgaa 1678801 atcgcctgtt ccgttgcatc agcacgtatc ccagctgcta caggcaatcg accaaaaccc 1678861 tcagcagagc caaatgatgt caaagctaaa ggaagcagtc acggtgcttt taaatagtga 1678921 aatcgatgtc catgcagaac ggctgattga taagcttatt tctttaaccg acaatacgaa 1678981 agcaccttct ccgacgaata cagctggaag cagggagctt agcacaccag ctggctcccc 1679041 cggaaaagcc agcctgccga ttgcaaatca cacagcagaa cagggaagca tacaagaaga 1679101 gcctgttaaa acagcagcag acattccaat taaagaagcc cgccagctgc tggtgaagct 1679161 gacggaatct gctgaaaaaa acagtctcca aattgtgaaa gaagcagcaa attggattaa 1679221 agcggctgct tcatcgggtg atagtaagtc acttgcagct tcagctgttt tacaggcggc 1679281 acaagtcaca gatcaggaag ccgaagtctt tttaaaggct gttcagcaga cagcacccca 1679341 tttggcggat aaggcagatg ttctttcttt cttatccaaa gtgaaaacgg caatcggcgc 1679401 aagggacgag gttgcgttca ttaaagcgtt tgaacaagga agcgcagtca catctggcga 1679461 aatgcaatcc atcaagctgg ctctttctgc cttaagagca tcgcatgagg tagccgaacc 1679521 agtcaaacaa gaagccgatc agctttttca taaattaaat ggccagcttt tcatgcagca 1679581 ggaccatcca tcatacagcc aaattgtaat gtcatttccg atgttttcga agtcaggggt 1679641 tcaggacatg actgttctgt ttaaaggaaa gaaagaagcg gatggaaagc ttgatccttc 1679701 ccattgccgc cttttgtttt tgctgcagct tgatacacta aaagaaaccg tcgttgattg 1679761 cttggtacag caaaaagtca tgaccattac aatagagact gatttcgagc tgcaggctgc 1679821 gatcgatccg atggtgcccg cgcttaaaca ggggctaaag gaaatggggt acagcctttc 1679881 aggggtaaac gctaaaaaaa gggttcacac cgaagaaaag gcttcaatcg atcaatatat 1679941 aacaagtatc agtgatcagg aagtggatgt gaaaatatga aagagcagac accgatcaga 1680001 aaagctgttg ctctccatta tgacgaacaa aaagacaagg cgccgagagt gattgccaca 1680061 gggaagggcc atgtagctga caacattata aaagaagcga aaaaagcagg ggtcccgatt 1680121 caagaagatc ggacccttgt cgaattaatg cgccatttga cggtagatga tcaaattcct 1680181 gaagctcttt atgaaacggt agccgagatt ttttcattca tttacaaatt ggacgaaagc 1680241 gtaaaaaaca aaaaatagct aaaatattcc ccatccttct ttgaaattta tgtttttaat 1680301 aaagtaaaag tttgaatgtt tagaaggatt aaaagatttt gcatcgaact gtagacaatt 1680361 cttccagtat tattatagaa tgaaagcgca gtctatttta gttttgttac ataagttagg 1680421 aggatgggaa atgaatatcc atgagtacca gggaaaagaa gtcctcagaa aatatggggt 1680481 atctgttcct gaaggtaaag tggcttttac agcagaagaa gcagttgaga gtgcaaagag 1680541 cttatccagc tcggtttatg tcgtaaaggc tcaaattcat gctggcggtc gaggcaaagc 1680601 tggtggggta aaaatagcaa aatcattaga cgaagtaaaa gcgtatgccg aagaactatt 1680661 agggaagacc ctagttacac atcagacggg tccggacggc caagtaataa aacgcttact 1680721 tattgaagaa ggctgcgata ttaaaaaaga atattacatc ggtctagtgc ttgaccgcgc 1680781 cacttcaaga atcgttttaa tggcttctga agaaggcgga acggaaattg aagaggttgc 1680841 ggagaaaaca ccagaaaaaa tcaaaaaagc tgtcattgat ccagctgttg gccttcaagg 1680901 ctatcaagcc agagaaattg cattcgctat taatattcca aaagagctcg tgggaaaagc 1680961 tgctaaattt atgcttggac tatataaagc gtttgttgag aaagactgct caatcgccga 1681021 aatcaatccg cttgttgtga ctggcgacgg aaatgtgatg gcgcttgatg caaaattgaa 1681081 ttttgacagc aatgcgttgt accgacaaaa ggacattatg gaatacagag atttggatga 1681141 agaagatccg aaagaaattg aagcgtccaa atatgatcta agctacattt cccttgatgg 1681201 aaatatcggc tgtatggtaa acggcgcggg acttgcaatg tctacgatgg atattatcaa 1681261 gcattatgga ggagaaccgg ccaacttcct tgatgtgggc ggcggtgcaa ccgcggaaaa 1681321 agtcacggaa gcatttaaaa tcattctttc tgatcaaaac gttaaaggga tttttgtcaa 1681381 cattttcggc ggcattatga aatgtgatgt catcgcagaa ggggttgttg aagcgactag 1681441 acaagttggt ttgacattgc cgcttgtcgt ccgtcttgaa ggcacaaacg tggatctagg 1681501 gaagaaaatc cttagtgaat caggattaaa cattacatct gcggaatcaa tggctgacgg 1681561 cgcgcagaaa atcgtatcct tagtttaaga aagaatgaaa ggcaggggac caaataatga 1681621 gtgttttcat taataaagat acaagagtta ttgtgcaagg gattacaggt tctaccgctt 1681681 tatttcatac gaagcagatg cttgaatacg gcacaaatat cgttggcggt gtaacacctg 1681741 gaaaaggcgg aacagaagcg gaaggtgttc ctgtatttaa tacagtggct gaagcagttc 1681801 aaacaaccgg cgctaacgcg tctgttatat atgtgcccgc accgtttgca gctgatgcga 1681861 ttatggaagc ggtagatgcg gagcttgatc tcgtgatttg tatcacagaa catatcccgg 1681921 ttttggatat ggtgaaggtc aaacgcttca tggaaggcaa gaaaacgaga ctgatagggc 1681981 cgaactgtcc tggtgtcatt acgcctgaag aatgtaaaat cggcattatg cccggataca 1682041 tccataaaaa gggtcatgta ggcgttgtat cacgttcagg aacattaaca tacgaagcgg 1682101 tgcaccagct ctcagaagcg ggtgtagggc aatctacagc tgttggaatc ggcggcgacc 1682161 ctgtaaatgg aacaaacttt attgacgttt taaaagcgtt taacgaagat cctgacacac 1682221 acgcagtcat catgattggc gaaatcggcg gtacggccga agaggaagcg gcagagtggg 1682281 taaaagccaa catgacaaaa ccggtagtcg gttttattgg cggtaaaaca gcacctcctg 1682341 ggaagcgcat ggggcatgca ggcgccatta tttccggcgg gaaagggaca gctgatgaaa 1682401 aaatcaaaac ccttaatgca tgcggaatcg aagttgcaga gacaccttct gtcatgggtg 1682461 aaaccttaat caaggtgctg aaagagaaga acttgttcga aacttgtaaa acgcattaat 1682521 aaaaaaggga cagccgtcaa ggctgttcct gctttttcta acaaaaggag gtcaatctat 1682581 tggatcaggc cgctgtctgc ctaacgattt gcagaatcaa tcaattatta tccccatccc 1682641 ttctattaaa atggtggaaa gccgatccgt ctatgtcgct gacatcaccc gtgttacaaa 1682701 cggttactcg tgatcaaata aaagcagctg cattaaaaaa cgaaatagaa caattttatc 1682761 caaagctccc gcgtgtactt gctgcttatc gtgagcaagg cattaacacc atccctattt 1682821 cttcaaagca atatcctttc tggcttaaaa gcatttatga tccccctgcc gtactgtttg 1682881 caaaaggtga tatgactctt ctttcgaaag ggagaaaaat tggaattgta ggcacaagaa 1682941 atccaacagc ttatgggaaa caagttgtca atcatcttac aaaagagatc tgtcgtaaag 1683001 gttgggtgat tgtcagcgga ctggcgtctg ggatagacgg aatgtcccat gctgcaagta 1683061 ttaaggcgaa ggggcggaca attggcgtca ttgcaggcgg atttcaacac atttatcccc 1683121 gagaaaacct tcagttagca gatcacatgg ctaaacacca tatcctgctg tcagagcacc 1683181 cacctgaaac taaaccccaa aaatggcatt tccctatgag aaaccgtatt atcagcggac 1683241 taagtgaagg cgttattgtc gttcagggca aagaaaaaag cggttcgctg attactgcct 1683301 atcaagcatt ggaacaaggg agagaggtat ttgccgtacc cggttcattg tttgaccctt 1683361 acgccggagg tcctataaaa ctgatccagc agggggctaa agccatatgg tcagcagagg 1683421 atattttcga ggaacttcct gagagaaacg ttcaatatac ggaacccttt tgaattatcg 1683481 tttgacaaac ggtattgtaa tatttaataa tagtgaggat ttaaagttgc atattgtttt 1683541 ctatttaatt aatgacgttc atgataaaga atgaaatgtt gaaagccaaa taaagacagc 1683601 tgcaaaaata aaattgaaat atcttgaaaa gagagagaac acctcttgag ggggatgaaa 1683661 atgtctgatt atctagtcat cgtggaatcg cccgctaagg cgaaaacgat tgaacgttac 1683721 ttaggtaaaa aatataaagt aaaagcatca atgggacatg tccgggatct tccaaaaagt 1683781 caaatgggag ttgacataga acagaatttt gaaccgaaat atattaccat tcgaggtaaa 1683841 ggcccggtat taaaagagct gaaaacggct gcgaaaaaag ccaaaaaagt gtatctcgca 1683901 gctgaccccg acagagaagg ggaagcgatt gcatggcatt tggcacacag tcttgattta 1683961 gatctcaact cagactgccg tgtggtgttt aacgaaatta caaaagacgc tattaaggaa 1684021 tcgtttaagc atccccgcat gatcaatatg gatttagtgg atgcacagca agcgagacgt 1684081 attttagaca ggcttgtcgg atataaaatc agtccaatct tatggaaaaa agtcaaaaaa 1684141 gggcttagcg caggacgcgt gcaatccgtt gccctccgtt tgattattga ccgtgaaaaa 1684201 gagattaacg actttaagcc tgaggaatat tggacaattg acggtacgtt cttaaaaggt 1684261 caagaaacct ttgaagcgag ctttttcggg aaaaacggca aaaaacttcc tttaaatagt 1684321 gaagctgatg taaaagagat tctttctcag ctcaaaggga atcaatatac agttgaaaaa 1684381 gtaaccaaaa aggaacgcaa acgtaatcct gctttgcctt ttaccacttc taccctgcag 1684441 caggaagcgg ctcgcaagct caatttcaga gcgaagaaaa cgatgatgat tgcacagcaa 1684501 ttatatgaag gaattgattt aggaagagaa ggaacggttg gtctgatcac gtatatgaga 1684561 acggattcaa cccgtatttc aaatacggct gttgatgaag cagctgcatt tattgatcag 1684621 acatatggaa aagagttcct aggcggaaaa cggaagcctg cgaaaaagaa tgaaaatgcc 1684681 caggatgccc acgaagcaat tcggccgaca tcagttctta gaaaaccaag tgaattaaaa 1684741 gcagtcctcg gcagagacca aatgagactg tataaattaa tttgggagcg ttttgttgcc 1684801 agccaaatgg caccggctgt tctcgataca atgagtgtcg acctgacaaa caacggtttg 1684861 acatttcgtg caaatggaag taaagtcaag ttttccgggt ttatgaaggt gtatgttgaa 1684921 ggaaaagacg atcaaatgga agaaaaagac cggatgctgc ctgacttaca agaaggcgac 1684981 acggtattat caaaagatat agaacctgag cagcatttta cccagccgcc tccgcgatat 1685041 actgaggccc ggcttgttaa aacccttgaa gaacgcggta tcggccgtcc atccacatat 1685101 gctccgacac ttgatactat tcagcggcgc ggctacgtgg cattggataa taaacgtttc 1685161 gttccgactg aattaggtca gatcgttctt gacttgatca tggagttttt ccctgagatc 1685221 attaacgttg agtttacagc taaaatggag agagatcttg atcatgttga agaaggaaat 1685281 accgaatggg tcaagattat cgataatttc tacaccgatt ttgaaaaacg cgtcaaaaaa 1685341 gccgaatcgg aaatgaagga agttgagatt gaaccagagt atgctggaga ggattgtgaa 1685401 ttgtgcagtt ctccaatggt atataaaatg ggacggtacg gtaaattctt agcttgctcc 1685461 aacttccctg actgccggaa cacgaaaccg attgtgaaac aaatcggtgt gaagtgcccg 1685521 agctgcggag aaggaaacat tgttgagcga aaatcgaaaa agaaacgggt gttttacggc 1685581 tgtgaccgtt atccggactg tgaattcgta tcatgggaca aaccaattga acgaaaatgc 1685641 ccgaaatgcg gaaaaatgct cgtcgagaaa aaactcaaaa aaggtataca agtccaatgc 1685701 gtggaatgcg attataagga agaaccacag aagtagcggt gagcagggtc ttgctcacct 1685761 tctttgtgtg ttaaaagaag gccttgaata ataaactagg agatgtgaaa gatgaaccaa 1685821 caaacagtga atgtaatcgg agccggactc gcaggaagtg aagcagcatg gcagcttgcc 1685881 aaacgtggga ttcaagtcaa attgtatgaa atgcggccag ttaaacaaac gcctgcgcat 1685941 catacagata aatttgctga gcttgtctgc agcaactctc ttcgctctaa tacacttgct 1686001 aacgctgtcg gtgtattaaa ggaagaaatg cgtgcgcttg attcagccat tatcgctgcg 1686061 gctgacgaat gttcggtgcc tgccgggggc gctcttgcag tagaccgtca tgaatttgcc 1686121 gcaagtgtga caaatcgggt gaaaaatcat ccaaacgtaa ccgttattaa tgaagaagtg 1686181 actgaaattc ctgaaggccc tactatcatc gcaacgggtc cgttaacatc tgaatcgctg 1686241 tctgcccagc tgaaggagct gactggagag gactatttat atttttatga cgcagcggcg 1686301 ccaattgtag aaaaagacag ccttgatatg gataaagtgt acctgaaatc ccgttatgat 1686361 aaaggtgaag cagcatattt gaactgcccg atgacagaag aagagtttga ccgttttcat 1686421 gaagcattaa catcagcaga aacagtgccg ttaaaagaat ttgaaaaaga gattttcttt 1686481 gaaggctgca tgccgattga agtcatggca aaacggggta agaaaacaat gcttttcggt 1686541 ccgatgaaac cagttggtct agagcatcct gttacaggaa aacgccctta tgccgtcgtt 1686601 cagctcagac aggatgatgc tgcgggaaca ctttataata ttgtaggatt ccagacacat 1686661 ttaaaatggg gagaccaaaa ggaagttctc aagttgattc caggacttga aaatgtagaa 1686721 atcgtcagat atggcgtgat gcatagaaac acatttatta actctccaag cctgttaaag 1686781 ccgacttatc aatttaaaaa ccgcagtgat ctgttctttg caggccaaat gacgggagta 1686841 gaaggatatg tggaatcagc tgcctcagga cttgtagcag gcattaatgc ggcgaagctt 1686901 gtattgggag aagagcttgt gatcttccct caggaaacag caattggcag tatggcacat 1686961 tatattacaa caacaaacca gaagaacttc cagccgatga atgcaaactt tgggcttttg 1687021 aaagaattgc cagttaaaat taaaaataaa aaagaacgaa atgaacaata cgcgaaccgt 1687081 gcgattgaaa caattcaaac aatttcgaaa acaatatagg tattgattgc aacctgagcg 1687141 cgatttgtga taccatttaa aagcccttcc tggggaggta ttaggcatgg agaatgttaa 1687201 gaatttcgta aagttattcg ttgaatattt acaaattgaa aaaaattatt cacaatatac 1687261 tattgtgaat tatgtggatt caattgaaga attcgagact ttcctgcgcg ttcaaggtat 1687321 aaatggattt gaagaagctg catatcaaga tactaggatt tttttgacag aagcctatga 1687381 aaaaggttta tcgagaagaa caataagcaa aaagatatct gcattaagaa gcttttataa 1687441 gtttctgatg cgggaaaagc ttattgaaga aaatccgttt cagcttgttc atctgccaaa 1687501 acaggagaaa cggataccga agtttctata tcaaaaagag cttgaggagc tgtttgaagt 1687561 ttcagatata agccagccgg ccggaatgag ggatcaagcg ctgttagagc tgctctatgc 1687621 cactggaatg agggtcagtg aatgctgttc cataactatt aacgacgttg atttatttat 1687681 ggacactgtg cttgttcacg gtaaaggcaa gaagcagcgc tatatcccct ttgggtctta 1687741 tgcccgcgaa gcgttgaagg tatacatgaa tagcggaaga cagtgcttgc tgatgaaggc 1687801 aaaagaacct catgatctat tattcgtaaa tcaaagaggc ggaccgctta cagcccgtgg 1687861 catcagacat attttaagcg ggcttgttca aaaagcgtca agcactttac atatccatcc 1687921 gcatatgctt cgacatacgt tcgccacgca tctgttaaat gaaggagcgg atttgagaag 1687981 cgttcaagaa ctgctcgggc attccaatct gtcttctaca cagatataca cgcacgtttc 1688041 gaaggaaatg ttgagaaaca catatatgtc tcaccatcca agagcattta agaaaaatta 1688101 aaggaggccc tttatgtcat cttttcatgc gaccacaata tttgccgtac agcataaagg 1688161 acgaagcgct atgtccggag acggccaagt aacatttggt caggctgttg tcatgaaaca 1688221 cacggcacgg aaagtgagaa aactgtttaa cggcaaagtt cttgctggtt ttgcgggatc 1688281 tgttgcagac gctttcactt tattcgaaaa gtttgaagct aagcttgaag aatataacgg 1688341 caacttaaaa cgggcggctg ttgagcttgc aaaggaatgg cgcagtgata aagtgctaag 1688401 aaagctcgaa gccatgctga ttgttatgaa tcaggatact ttgcttctcg tatcgggaac 1688461 aggcgaggtg atcgaaccag atgacggcat tctcgcgatt ggatcaggag gcaattacgc 1688521 tttggcagcg ggaagagcac tgaaaaagca tgccggggaa agcatgtctg caagtgagat 1688581 tgccagagcc gcgttagaaa cagcaggcga aatttgtgtt tacacgaacg atcaaatcat 1688641 actggaagag cttgaataga aaggacttga ggcgcatgga aaaaaaaccg ttaactccta 1688701 gacagattgt agatcggtta gaccaatata ttgtcggtca gcaaaatgcg aaaaaagctg 1688761 tcgccgtggc attaagaaac cgctatagaa gaagtcttct ggatgaaaag ctgaaggacg 1688821 aggtcgttcc gaaaaacatt ttaatgatgg gtcctaccgg cgtcgggaaa actgaaattg 1688881 ccagacgaat cgctaagctt tcaggtgcgc catttatcaa aattgaagct actaaattta 1688941 ccgaagtcgg ctatgtaggc agagatgttg aatcaatggt cagagatctt gtggagactt 1689001 ctgttcggct tataaaagaa gagaaaatga atgaagtaaa ggaacaggca gaagaaaatg 1689061 caaacaaacg cattgttcgt ctgttagttc ctgggaagaa aaaacaatct ggtgttaaaa 1689121 atccgtttga aatgtttttt ggaggcagcc agccgaatgg tgaagatgag gcggagagcc 1689181 aggaagaagc aaacatcgaa gaaaaaagaa aacgaatggc gcatcagctg gctttaggag 1689241 agctcgaaga ctactatgta acagtagaag tcgaagaaca gcagccttct atgtttgaca 1689301 tgctgcaggg ctcgggtatg gagcagatgg gtatgaacat gcaggatgcg ctgagcggat 1689361 taatgccaaa gaaaaagaag cggcgcaaaa tgacagtcag agaagccaga aaagtcctga 1689421 cgaatgaaga agcaagcaaa ctcatcgata tggatgaagt cggccaggaa gctgttcaga 1689481 gagcagaaga gagcgggatt atctttatcg atgagattga taaaatcgca aagaacggcg 1689541 gtgcatcttc ttctgccgat gtttcaagag aaggtgttca gcgggatatc cttccgattg 1689601 ttgaaggttc taccgttgtc acaaaatatg gttctgtaaa aacagaccat gtattattta 1689661 ttgcagcagg agcgtttcat atggccaaac cgtctgattt gattcctgag ctgcaggggc 1689721 gtttcccgat tcgtgtagaa ctgaacaaac tcacggtaga cgacttcgtg agaattttgg 1689781 ttgagccgga taatgcgctg ctgaaacaat atcaggcatt attgcagaca gaaggtatat 1689841 ctcttgaatt ttctgacgaa gctattcata agattgctga agttgcttat catgtgaacc 1689901 aggacacaga taatatcggt gcgagacgcc ttcatacaat acttgaacgc ctattagaag 1689961 atttgtcgtt tgaagctcca gatgtaacga tggagaaaat aacgattaca ccacagtatg 1690021 tcgaagaaaa gctcggaacg atagccaaaa acaaagattt aagtcaattt atattgtgaa 1690081 aaatttaata tgaggaatgt ttaggaggat tatttatcat ggctttatta caaaaaacaa 1690141 gaattattaa ctccatgctg caagctgcgg cagggaaacc ggtaaacttc aaggaaatgg 1690201 cggagacgct gcgggatgta attgattcca atattttcgt tgtaagccgc agagggaaac 1690261 tccttgggta ttcaattaac cagcaaattg aaaatgatcg tatgaaaaaa atgcttgagg 1690321 atcgtcaatt ccctgaagaa tatacgaaaa atctgtttaa tgtccctgaa acatcttcta 1690381 acttggatat taatagtgaa tatactgctt tccctgttga gaacagagac ctgtttcaag 1690441 ctggtttaac aacaattgtg ccgatcatcg gaggcgggga aagattagga acacttattc 1690501 tttcgcgttt acaagatcaa ttcaatgacg atgacttaat tctagctgaa tacggcgcaa 1690561 cagttgtcgg aatggaaatc ctaagagaaa aagcagaaga aattgaagag gaagcaagaa 1690621 gcaaagctgt cgtacaaatg gctatcagct cgctttctta cagtgagctt gaagcaattg 1690681 agcacatttt tgaggagctt gacggaaatg aaggtcttct tgttgcaagt aaaattgctg 1690741 accgtgtcgg cattacccgt tctgttattg tgaacgcact cagaaagctg gagagcgccg 1690801 gtgttatcga gtctagatca ttaggaatga aaggtactta tatcaaggta ctaaacaaca 1690861 aattcctaat tgaattagaa aatctaaaat ctcattaatc acaaaaagaa ccctttttga 1690921 gggttctttt tttatttcaa ataaaggaaa tcaataagct ttatttcctg ggttgaaagt 1690981 ctttctatgt aataatttta ataaattttg catttttctt caaaaagttt caaaaatgcc 1691041 gaaaagaaag gagaaaaaac agaaattctg ctattttcag gcttatatca aggcgagaaa 1691101 tgtagttcta acaatctagg actttatacc tagttgcaaa atagataatt gtgaggacat 1691161 ttttttacac gaacttcata gactttatgc ctgttatttc ttacaataag catatagttt 1691221 tacaattctc gacaaggata ttgagggtga aaaaaactga aatggaggta agtggatttg 1691281 agcttatttt ctggaacgat acaaaatctt gaaaatgcct tgagcagagc ggatattaag 1691341 caaaaagtca taactaataa tatcgccaat atagatacac cgaactataa ggcaaaaaaa 1691401 gtctctttcc aaaatttatt agatcaagaa tcctcgcgtc ttgaagcgat aaaaacagac 1691461 tatcgtcatg ttgatttttc tgatactgat tcgaattatt caattgttgc gagcggagat 1691521 acatcgtatc agcaaaacgg aaacaatgtt gatgttgaca aagagatgac agaattggcg 1691581 caaaatcaaa tcaactatca agctttggtt gaaagaatga acggtaaatt taattcgctg 1691641 aagaccgtat taacaggagg aaaatgatga cagcttttca tagcttaaat gtttcagcat 1691701 cggctttaac agctcagcga gtcagaatgg acgttgtatc atctaactta gcaaatatgg 1691761 atacgacaag agctaagcag gtgaatggag agtgggtgcc ttacagaaga aaaatggttt 1691821 cccttcagtc aaaaggtgaa tcgttctctt ccattctcaa ttctcaaatg agcggaagcg 1691881 ggaatgctgg aaacggtgtg aaggtttcaa aaattacgga ggatgattcg gattttaatc 1691941 ttgtctatga tccgacagac cctgatgcaa acgctgaagg atatgtacaa aagcctaatg 1692001 ttgatccatt aaaggaaatg gttgatcttg tcagcagcac tagatcatac gaggcgaatg 1692061 tcacggcgat gaatgccaca aagggaatgc tgatgaaggc gttagaaatc ggaaagtagg 1692121 tgaatgaatg tgattaatgc aatttctcct tttcaggttc aaaatactca aaacactcaa 1692181 aatgcaacaa atcaagtaaa caatagccaa aaaacagatt cttcaaatca aacaagcttt 1692241 tcggagcttt taaaaaactc tattagttcg ttaaatgagt cccaagtagc ttctgacaac 1692301 atgactaatg ccttggctgc aggaaaagat gtaaatcttg atgaggtcat gatcgctgct 1692361 caaaaagcta gcatctctct aactgcagca acagagttcc gcaataaagc tgtggaagct 1692421 tatcaggaga ttatgagaat gcaaatgtag ggggtctgac gatttagaga aagagtggaa 1692481 tgaccggggg ttaacatgaa tcgtactcta atgcaaatga aaaacaaaac gagtgagttt 1692541 tggaaaaata gatctaaatt acaaaagatt ttaatggtta gtgctttagc ggcaattatt 1692601 attattggaa ttattattag tgtttttgct tcaaattcta aaatggcgcc gctgtacaaa 1692661 gatttgtctg ccgaagaagc aggacaaatc aaagaagaat tggatgcaaa aaaagtgcca 1692721 aacgaacttt cgaatggcgg tacagtgatt agtgttccgg aggatcaggt tgattctttg 1692781 aaagtgcaga tggctgcaga aggacttcct aaaacgggat caattgatta ttcgtttttt 1692841 ggacagaatg ccggctttgg tttgacagac aatgagtttg atatggtgaa agtgaaagct 1692901 acacagacag aactgtcaaa cttgatcaat gaaatggacg gtattaaaaa ttcaaaagta 1692961 atgattaatc tcccgaaaga cgctgtgttt gtcggtgaag agcaatctgc agcatctgca 1693021 tcaatcgttt tgcagattca accgggttat acacttgatc aaagccaaat caacggatta 1693081 tatcatctgg tatctaaaag cgtgccaaac ctaaaagaag ataacatcgt catcatggac 1693141 caaaattcta catactacga caaatcagac agcgatgcag ggtcctacgc ggatagttat 1693201 tcttctcagc aaggaattaa gtctcaagtt gaaaaagaca ttcaaaaaca tgtacagtca 1693261 ctgctgggta cgatgatggg ccaagataaa gtcgttgtct ccgttacagc agacattgat 1693321 ttcacaaaag aaaatcggac agaagacatt gtcgaacctg tggataaaga aaacatggaa 1693381 ggcattgcag tcagcgctga aaaggtatct gaaacatatc agggcgacgg tgcagccaac 1693441 ggcggaactg ccggaaccgg cgaggaagat gttacaaatt ataaggctga cggtgaaaat 1693501 accgaaagcg ggaactacga aaaaaacagc aacaaaatca attacgaggt taaccgaatt 1693561 cataaagaaa tcgctgaaag tccttataag gtcagagatt tagggattca agtaatggta 1693621 gagccgcctg atgccaaaaa cactgcgtcg ctatcaactg aaagacagga tgatatacaa 1693681 aaaatccttt caactgtagt cagaacatct ttggataaag atgaaacgca aaatcagaat 1693741 ttatctgatg ctgatatcaa taataagatt gttgtttccg ttcagccatt cgacggaaaa 1693801 gtcaatttgg atacaaatac ggaagaatcc tcaggtatcc cgctgtgggc atatattgta 1693861 ggcggtgttt taatcgcagc gatcattgtt ctgatcatta tgcttatcag aaagaaacgg 1693921 gcgcaagagg atgaatttga ggaatatgag tatgaggttc ctcaagaacc aatcaatttg 1693981 cctgatatca acgaagagga aaatgaaaca gcggaatcag tcagacgaaa acagcttgaa 1694041 aagatggcga aagacaagcc ggaagatttt gcaaaactgc tgagaagctg gctggccgag 1694101 gattaggagg aattagaaat ggcgagacgt gatcaagata agcttacagg aaaacaaaaa 1694161 gcagccattc tcatgatttc cttggggtta gatgtgtcag cttctgtcta taagcactta 1694221 accgatgaag aaattgaaag gcttactctg gaaatatcag gtgttcgaag cgtcgatcat 1694281 caaaaaaagg atgaaatcat agaagaattt cataatatag ccattgcgca agattatatt 1694341 tctcaaggcg gtttaagcta tgcaagacaa gttctggaaa aggcgcttgg agaggataag 1694401 gcggagaaca ttctaaacag gctgacttct tctttgcagg ttaaaccatt tgattttgcc 1694461 agaaaagcgg agccagaaca aattttgaat tttatccagc aagagcatcc gcagacgatg 1694521 gcgttaatct tgtcttattt agatccagtg caggccgggc aaattttatc cgagctgaac 1694581 cctgaagtgc aggctgaggt tgcgagaaga atcgcggtca tggatagaac gtctccagaa 1694641 ataattaacg aggtagaacg gattctggaa caaaaattat cttctgcatt tactcaggat 1694701 tatacacaaa caggcggaat tgaagctgtt gtggaagtgt taaacggggt agacagaggg 1694761 acagagaaga cgatcttgga ttcattggaa attcaggatc ccgatcttgc tgaagagatt 1694821 aaaaagcgga tgtttgtctt cgaagatatt gtcacacttg ataaccgtgc aattcagaga 1694881 gtcattcgcg atgttgagaa cgacgatttg ctcctttcat taaaggttgc aagcgaggaa 1694941 gtcaaagaaa ttgtgttcaa caatatgtca cagcgtatgg ttgaaacctt caaagaagaa 1695001 atggagttta tgggccctgt acgtttgaaa gatgtagaag aagctcaatc aagaattgta 1695061 agcatcgtca gaaagcttga agaagccggt gaaattgtaa tagcaagagg cggaggggat 1695121 gatattattg tctaatatca ttaaacaaga atcatctatt tctccacaaa aggaaaaaag 1695181 aaaactttct atacaagagg tgcgtattga tcattctcac cttttgcagg ctgaagagaa 1695241 cccggaggcg cttatggccc gagtgaaaga ggaagctgac cggatttctg agcaggcaaa 1695301 cagtcatata gaaaatattc gccgtcaaat tgaacaggag aaaaacgatt gggcggctga 1695361 aaaacagaag cttattgaag aagcaaaagc cgagggcttt gaacaaggag tagcgctggg 1695421 caaagctgag gcaatgaaac agtatgcaga actgatcggc caagcaaaca gtataactga 1695481 aatgtccaga aaagctgttg aggacaagct tgaagacgct aatgaagaaa tcgttgagct 1695541 tgccgttgcc ctagcaaaaa aagtttggca gcaaaagtct gatgataaag aggctttcct 1695601 cctgcttgta caacaggtta taaacgaagt gaaggaatat gacgatatat caatttatgt 1695661 tgatccatat tactatgaga caatctttca gcaaaaagat gaaatccagc agcttcttta 1695721 taaagaatgt cggcttggca tatatgctga tgaaaaagct caaaaaggaa cctgttatat 1695781 tgaaactcct tttggcaggg tagatgcgag tgttgacaca caattgatgc aattgaaaga 1695841 taaacttctg acagcgctgg aagcaggtgc agctgaatga agacacagag tctgatagat 1695901 tgtatagaaa tgacagactc gtataaacgg tacggaaaag tcaagcgggt aatcggcttg 1695961 atgattgaat caaaagggcc agcaagctca attggtgacc tgtgcctgat ttatgcaaaa 1696021 ggacagtctg ggaaagtcat taaagctgag gtagtcggct tccaggaaga aaatattttg 1696081 cttatgcctt atttagaggc tgcgagcatt gcacctggca gcattgtaga agctactggg 1696141 gaatcacttc gggttaaagt tgggaccgga ctgatcggac aagtcatcga tgcttttgga 1696201 gaaccgcttg acggaaagct tctgccgaaa gggctttcgc ctgtatcaac ggagcaatca 1696261 ccgcctaacc cgatgaaacg gccgcctatc cgtgaaaaga tgggtgttgg agtcagatca 1696321 attgacagct tgctgacagt cggtaaaggc cagcggattg gaatttttgc aggaagcggt 1696381 gtcggaaaaa gcaccttaat ggggatgatc gccaagcaga cagaggctga cttaaacgtc 1696441 attgcacttg tcggagaacg cggacgagag gttcgggagt ttattgaaaa agatctgggg 1696501 aaagaggggc tgaaacgatc gattgtagtc gttgccacct cagaccagcc agcattaatg 1696561 agattgaaag cggcatatac agcgactgca attgccgagt atttccgaga taaaggccaa 1696621 aatgtcatgt ttatgatgga ttctgttaca agggtggcaa tggcgcagcg agagattgga 1696681 ctggctgcag gagagcctcc gacgacaaaa ggctatacac cttcagtgtt cgctatttta 1696741 cctcgtttac tagaacgaac aggtgcaaac gagcatggaa ccattacggc attttataca 1696801 gtgttggtag atggggatga catgaatgag ccgattgccg ataccgtacg cggaatttta 1696861 gacgggcata ttgtgttgga cagggcgctt gccaataaag gccagtttcc tgcagttaac 1696921 gtactaaaaa gcatcagcag ggtgatgtca aacatttcaa caaaacagca tctggatgcg 1696981 gcaaataaat tccgtgaact tttatcgaca tatcaaaatt cggaagatct cattaatatc 1697041 ggagcttaca aaagaggatc atccagagaa attgatgaag cgatacaatt ttatccgcag 1697101 cttattcaat ttttaaagca gggaacagac gaaccggctt tattggaaga aagcattgct 1697161 gcattaacta gtttgacagg aaatgaggaa taaacgtggc ttatcaattt agattccaaa 1697221 agctgctgga actaaaagaa aatgaaaaag accaatcctt atccgaatat cagcaatcag 1697281 tttctgaatt tgaaaacgtt gctgaaaaat tatatgagaa tatgagcaaa aaggaattgc 1697341 tggaacaaaa taaggaaaag aaattaaaaa gcggcatgag tgtacaagaa atgaggcact 1697401 accaacaatt tgtctcaaat cttgataata cgatctatca ctatcaaaag cttgtcatta 1697461 tgaaaagaaa tcaaatgaat caaaaacaag aaattttgac agagaaaaac attgaagtga 1697521 aaaagtttga aaaaatgcgt gaaaaacagt ttaaaatgtt tgctcttgaa gataaagctg 1697581 cagaaatgaa agaaatggac gatatttcga ttaagcagtt tatgattcaa ggccattagg 1697641 agcgaatgta atgtccggca aaaagaaaga atcaggtaag ttccgttcgg ttttgcttat 1697701 cattatcctc ccgctgatgt ttctattaat cgcagggggg attgttcttt gggctgctgg 1697761 tatcaatgtc ttaaagccga tacaggatgc tgcggcaaaa acgccggttc ttaaagaatt 1697821 ggtccctgaa accgaaaata aaaaaggcgc agcatcaagt aaggatagca gtaatacggc 1697881 agctctggaa aagaccatta aggatcaaaa aagtgaaatc agtatattga ataaagattt 1697941 agaaacaagt aaatcagaaa tcgacaggct caatcaaaag atccgttcac ttgaaaagac 1698001 ggctgaggat caaaaaaagt catcagaaga tcatactgaa ggatcagcag actcgaaagc 1698061 ttcttctgaa aatgacaaag tgatcagtgt gtacaaaagc atggacagcg gaaaggctgc 1698121 taaaattatt gcccaattaa aggagcaaga agcactgaaa atattgaatg gcctaagcaa 1698181 aaagcagctt gctgacatat tggcgaaaat gactcctgag caagcagcaa cctatacaga 1698241 aaaaattgct gccagccaag aataggggga atgaaaggtg aagctgcttg aattagccgg 1698301 acctttgctg caaaccacaa cgggttctgc cgctaaaaac atgaaaagta gccagggagt 1698361 ttttcaaaac tggcttatgt ctgaggctgg attgaaggaa ctttcagaac aaggaaaggg 1698421 aactcctaat tctgaagatc agcttttagc agatgcgctt aaaaagatcg gtgaatggct 1698481 aaatgcaagt cctgaagatc aagacaaaca aaatgcggat cttttgcaaa cattaagcaa 1698541 actgacaggg aagcaattgg atgcgaatgc tctgcaaatg ttgcaaaatc ttttgcaagc 1698601 agttgaatca aaaatgtcag gcgggacgga tcaattgctc acagaaacgg agaaaatctt 1698661 ttcagaagct aaaacggctc tgagtgccaa tgattctgct tctgacatta atggagcact 1698721 gaagtctgat aaagagcaat caaatcagga aaatgaagta tccgagcctg caaaagagct 1698781 tatctatatc cagatgttca ttagccagct cgtagaaggg aataagctga ctgatctcgg 1698841 gaatggcaat gaagctcatg ccatttacca aaatggagat caattccttt ctgcattaga 1698901 aaagaagggt gtatctcaac aactaattca ggatcttaaa cagcaaatat tcactaaagc 1698961 tgagtcaagt tcaaaacttt actcgatgac agcgtcagag ctgaaaagtt ttcaaagctt 1699021 aatggatcaa atgtctatgc ttcctcaaaa agggaccaaa gaatggagtt tagctgaaag 1699081 ccagctgaaa gccttcttgt tatcgaaatc atccgaatca tcacaagact ttgggaagag 1699141 tgttctcaca ccgctctcgc agagttcatc cagcaaaaat gcatcggatg tttctggaag 1699201 tattcagcct gtagatagta aatcaggact ccaaatgctg ttttcggggt atcggggcat 1699261 aggaggagtt caaacacttg atctgcagca gatgtcatct gatataccaa atgccgaaac 1699321 aaaaacggtg gctgatcaag tgattaatgc gtggaagcag atgaaatata cgcctttcgg 1699381 cagatcgacg ggaagtttca ctattcggct gaaccctgaa catttaggat ttgtcacaat 1699441 caagctgaca aatgaaaatg gaatgtttca gagtaaaatc atagcatcta gccaatcagc 1699501 aaaagaattg cttgaacagc atcttcctca gctgaagcaa tcattgccga atatggccgt 1699561 ccaaattgac cgttttactc ttccggtcca aagcggggat cagccgatat acggccagct 1699621 tgctgatgaa cagaaacagc agcaagaggg gcagagacag caaagacaga aaaagcaatc 1699681 aaatgatttt ggcgatctgc tcgatgaagt gtcgatggtt gaaatggagg aagaagaatg 1699741 acttctataa gttcagaata taaactgcct gaaaaaacga acactgtgtc gacgaacaac 1699801 agcagcttgg ggaaagacga gtttttaaaa atattaatga ctcaagttca aaaccaagat 1699861 ccgcttaacc cgattgacga taaagaattt atcagccaga tggcgacttt ttcaagcttg 1699921 gagcaaatga tgaatctgaa tacgacaatg actcaattcg ttgaaaacca agatccgttt 1699981 acaacgtatg ttgattggat gggaaaagaa gtatcttgga ctgatggtaa aagtgcaaca 1700041 gataaaacag gcacagtaag ctctgttaaa cattttaaag gaaattatta tctcgttctt 1700101 gatgatggga ccgagatcag tcctgcgaat gtcatgtctg tgggacaatc atctaaataa 1700161 aaacatctgg gggaatatat tatgttacgt tcactttatt ctggaatcag cggtatgaaa 1700221 aactttcaaa caaagcttga cgtaatcggt aacaacattg ccaacgtaaa tacagtagga 1700281 ttcaaaaaga gccgtgtgac ctttaaagat atggtaagcc aaacgattgc cggcggttct 1700341 gctgctggtg caacaatcgg cggaacaaac tctaagcaaa tcggtttagg ttcatcatct 1700401 ggcacaattg atacaattca ttcaacaagc gcgacacaaa gcacaggaag aacacttgat 1700461 ttagcaattg acggcgacgg ttacttccga attgatacag gtgacgggac agcttataca 1700521 agagcaggga acttctattt agataatact ggaacactgg ttacaggtga tggctaccat 1700581 gtactaaata tgaatggcgg aacaattaaa attcctactg atgctcaaag ctttagcatt 1700641 ggttctgatg gaaaggtgtc aattgttgat gctgagggga aaacacaaga cgggggacaa 1700701 atcgggattg ttacttttgc caacagtgat ggattggata aaatcggaag caacctatac 1700761 cgtgaatctt taaactctgg aacggccagt gcagcgaacc agcctggtga cggcggaact 1700821 ggtgctctta aatcaggatt tctcgaaatg tctaacgtcg atttaactga cgaatttact 1700881 gaaatgatcg tagcccagcg cggattccaa tcaaactcaa aaattattac aacatctgat 1700941 gaaatccttc aagaactggt taaccttaaa cgttaaggag ggaggggagg cgagtaatcg 1701001 cttctccgct gttttatgat taaagtaacc cgtttgaacg ggcagccctt tacactgaat 1701061 gcgctattta ttgaacagat tgaatgtttt ccggatacta caattactct gtcaaatggt 1701121 aagaagtttg tagtaaaaga agatgaagaa gctgttctgg aaaagatcgc agctttctac 1701181 cgaaaaatac aaatatttgc aatggatcaa ggaatagagg aaccggaatg aagaaaaagt 1701241 taatgatcat attactaatt attcttatcg taattggtgc tctcggggcg gcggcttatt 1701301 ttgttttagg cggaaagtcc gaaaaaagtg aagcgaaaaa aagtattgat gaaatcgttg 1701361 cgtcttctgt tgatgtagaa gagatcacaa caaatttaaa gtctgataac attatccgtc 1701421 ttgctattaa acttgaaact gattctgata aatcaaaaga agaacttgag aaacgtgatt 1701481 tccaagtgaa agacgctgtt atatcactgc tggctgatac gaatgctgat cagattgagg 1701541 gagacaaggg aaaagaaacc tttaagaagg aactaaaaga taaaataaat agctacctcc 1701601 aagaaggaaa agtagaaaaa gtgtatatta cctcctttaa tctgcaataa agcataattt 1701661 gacagaatac ggaggtgagg aaaatgtcag gagaagttct ctcccaaaat gaaatagatg 1701721 cactgctctc tgcaatatca actggtgaaa tggacgctga agagctgaaa aaagaagaaa 1701781 aagagaagaa agtcaaggtt tatgatttca aacgtgcgct gcggttttct aaggatcaga 1701841 tccgcagttt aacgagaatt catgacaatt ttgcaagact tcttaccact catttttctg 1701901 ctcagctcag aacctatatt cacatatctg tcagttctgt tgatcaggtt ccgtatgagg 1701961 aatttatcag atcgattcca aacatgacga ttctgaatct atttgatgtt catccgatgg 1702021 aaggaagaat tatgatggag gtcaacccca cgatagctta tacgatgatg gatcgagtca 1702081 tgggcgggat tggaatcagt cataacaagg ttgacagttt gacagaaatt gaaacaaaaa 1702141 tcatttctaa tttatttgaa aatgcactgg gtaattataa agaagcttgg cagtcaattg 1702201 ctgatattga accggaaatg actgagtttg aagtgaatcc gcaatttgtt cagatggtat 1702261 ctcctaatga aacagtcgtg gtgatctcgc tcaatactca aattggtgaa atcagcggtg 1702321 tcattaatct ctgtatcccg catattgtac tcgagccgct cataccgaag ctttcagtcc 1702381 actattggat gcaatcagac cgaaatgagc caaagcctga ggaaacaaag tcgcttgaaa 1702441 aacgtatcat gacagcacaa atacctgtcg tggccgagct cggcacatct gaactgacga 1702501 tagaagagtt tttaagttta gaagtcggag actgcataac tttggacaaa tcagtcacgg 1702561 atcctcttac tgtattggtc ggagataagc cgaaattttt aggacaagcc ggccgggtga 1702621 atcgaaaaca ggcagtgcaa attttagatc acgacataag aggtgaacaa gatggagaat 1702681 aatagattat ctcaagatga gattgacgcg cttcttaacg gtactggcag cacgcttgat 1702741 gagccagaga ttccggaagt agatgactta tcggaaatgg agcgtgatgc gatcggtgaa 1702801 atcggtaata tttcattcgg cagttctgcg acagcactgt caacgctttt aaatcaaaag 1702861 gtcgatatta cgactccaag cgtaacggtc attccaagaa gtaaaatcag cgatgcgttt 1702921 cctgaaccgt atgtagcgat tgaagtgaat tatacggagg gcttcagcgg aagcaacctg 1702981 ttagtcgtgg aacaaagtga cgcggcgatc attgcggact taatgatcgg gggagacgga 1703041 aaaggtgcgg acccttcact gggtgaaatc catttaagtg cggttcaaga agcaatgaac 1703101 caaatgatgg gatcggctgc cacatcaatg tctactgtat tcagtaaaaa aattgatatt 1703161 tcacctcctc gggttgaatt gctggatgtt actgaagaaa agggtacaga ccgtattcct 1703221 gatgatgaaa tgctggtgaa agtttctttc aacttaaagg tgggagaatt aatagactcc 1703281 agcattatgc aactttaccc attgacattt gcgaaagatt taatttcaag ccttatgaac 1703341 tcagaaagtg cagaggaaga agaaacggtg cagcctgaag ttacatacga acagccgaaa 1703401 gagcctgtga cgccagagcc gcgtattgaa ccgaagcaac agcagcagcc gccaaaaagg 1703461 cagggaacag caaaaaaagc agcgccagtt caggtttcac cggtggaatt ttccgcgttt 1703521 gatccaaacg aagctgtaca agcccctatt cataatctgg atatgctttt ggatatcccg 1703581 ctttcgatta ctgttgagct tggcagaacg aagagaagcg taaaagagat tttagagctt 1703641 tctgccggaa gtattatcga gcttgataaa ttagccggtg agcctgtaga tattttagtt 1703701 aatcagcgta tcgttgccaa aggcgaggtc gttgtcattg aagaaaactt cggagtgaga 1703761 gtcactgaca ttttaagcca ggcagagcgc attaataatt taaaataacg aaacacaagg 1703821 agagagatag attatggcac atagaatttt aattgtagat gacgcagcat ttatgcgaat 1703881 gatgattaaa gatattttgg ttaaaaatgg ttttgaagtt gtggcggaag ctgaaaatgg 1703941 agcacaagcg gtagagaaat ataaagagca ttcacctgac cttgttacta tggatatcac 1704001 gatgccagaa atggatggta ttacagcatt aaaagaaatt aaacaaattg atgcgcaggc 1704061 aagaatcatc atgtgttctg ctatgggaca gcaatcaatg gttattgatg ccattcaggc 1704121 cggcgctaag gatttcattg tgaaaccttt ccaggctgac cgtgtgcttg aagcaatcaa 1704181 caaaacatta aattaaaggg tgtacgactg ttgaaaaaga gtcaatattt tattgttttt 1704241 atttgttttt tcgttttatt cagtgtacat ccgattgctg ctgccgcggc agactctgat 1704301 aattcaactg taaacgaatg gtttcaaaag aaagatgaaa aaactgcaga tcaatcagag 1704361 caaaagaaag aaaaaacaac aaaaactgct gatgagacgg agggagcggc tgctccttct 1704421 gtctcagctt ttgattttgt aaagatgatt ttcgctttac tgtttgttat cgtgctgatt 1704481 tacgggctgg ttaagctcat gaacaaaaga aatcggctcc taaagccttt tcaatatgtt 1704541 gaaaatattg gcggcacatc ggtcggtcag aacagatcca tacaattgat caaggtcggg 1704601 aaaagtgtgc tcgtcgtcgg tgtaggagag acgatccagc tgctgaaaga aattgaggat 1704661 gaaaaagaga ttgaagtcat tctcagtcag catgaagagg caatgtcaag caaaatagag 1704721 tggcaaaagt ttgtgaagcc gcttaagagt tctgaacatc agccgcagca aaaactgcct 1704781 tcattttcaa aagcattaaa agagcaactt gaagagttaa aacaaaaccg ttctgaagga 1704841 aagaagaaag gcccacgtca tcatgaatga gtttataaat attttcagtt caagcgatcc 1704901 ggaaaacgta agttcgactg ttaaattact attattgtta actgtatttt cagtggcgcc 1704961 tggaatattg attcttatga cttgttttac tcgcatcgtc attgttctgt catttgtcag 1705021 aacttcactt gcgacgcaat ctatgccccc aaaccaggtt ctaatcgggc ttgcgctgtt 1705081 tttaacattt tttattatgg ctcctacttt ttcagaaatt aataaagaag cgctgacccc 1705141 attaatggac aacaaaatca gcttggatga agcgtatacg aaagctgagg aaccgattaa 1705201 agaatttatg agtaaacaca caaggcagaa ggatctggcg ctgtttatga attacgcgaa 1705261 aatggataaa cctgaatcat taaaggatat tccgttaaca acaatggttc cggcttttgc 1705321 catatcggag cttaaaacag catttcaaat aggttttatg atttttatcc cttttttaat 1705381 tatagatatg gtagtggcga gcgtcttgat gtcaatggga atgatgatgc tgcctccagt 1705441 tatgatttct ctgcccttta aaatattact ttttgttttg gtagacggct ggtatttaat 1705501 tgtgaaatct ttgcttcaga gcttttaggg taggtgctaa acgtgagttc agaatttgta 1705561 atttctatgg cggaaaaagc cgtatacgta acgctgatga tcagcgggcc attattggct 1705621 attgctttac tggtcggttt aattgtcagc atatttcagg cgacaactca aatccaggaa 1705681 cagactttgg cgtttattcc gaaaatcgtg gcggttctcc tggctctcat tttttttggt 1705741 ccgtggatgc tgtcgacgat tctttcattt acaacagagc tgttttctaa tttaaatcgt 1705801 tttgcagggt aatgtagaga tgaattcaat tattgactta tttcctgctt ttttattggt 1705861 ttttattaga atctctgctt tttttgtaac gattccgcta tttggacatc gaaatgtgcc 1705921 agctgttcat cgcataggtt ttgctttttt tcttgcggtc atttgtttca gcaccattga 1705981 taaaccgccc tctttggaga tagatgagca ctatatgctt ttggcgttta aagaagcttt 1706041 ggtcggccta tgtctgggtt taattgctta tatgatgatt gccgcagtgc agattgccgg 1706101 ctcgtttatt gattttcaaa tgggattttc aatagcaaac gttattgatc cgcaaaccgg 1706161 tgcacaaagt ccgttgattg gccagtttat ctatacgatg gcacttttgt ttatgctgag 1706221 tgtcaatgcc caccatttgt tgctggatgg tatttactac agctttcagt atatttcagt 1706281 tgatcaggca tttccgaatt tcggcgatga aaagtttgcc tattttattg cgaaaagctt 1706341 taatgcaatg tttattatcg cttttcaaat gtcagcgccg gttgtggcca gtttgtttct 1706401 agttgattta gcattaggta tcgtggctcg aactgttccg cagttaaatg tatttgtggt 1706461 cggtctgcct ttaaagatcg ctgtcagttt cattatgctc attgtatgta tgtccgttat 1706521 cttcgtcgtt gtccggaatg ttttcagttt aacgattgaa acgatgcgga atcttttagc 1706581 attggtcggt gtttcttaat gaagcttaga gttgacctgc agttttttgc gggagagaag 1706641 acagaaaaag ccactccgaa aaaacggaag gatacgcgaa aaaaagggca ggtagccaaa 1706701 agctcggatg tcaataccgc cgtttcttta ctggtaatat tcctttcgct tattgcaatt 1706761 ggtccgtata tgagagacag gctgctgtca ttcatagaaa cattttatac cgaatcgctc 1706821 acaatgaagc tctcagaatc aaatgtgcat acattgtttg tcagcttatt aaaggatatg 1706881 ggcatgatac tcgcaccgat cttgcttgtt gctcttgttg caggagtcgt aagcaactat 1706941 atgcaggttg ggttcttgtt ttctgctgaa gtgatacagc ctaagcttga aaaactggat 1707001 ccgatcaaag gctttaaacg aatatacagt atgagggcga ttgtagagct gattaaatca 1707061 attttgaaaa tcgtagtcgt cggttttgcg gcttttgctg tgctttggct gcattatgga 1707121 gaaattctcc ggcttcctct cctgacaccc gaagaggcac tttctttcgt ttcaaaactc 1707181 actttgtgga tgggactaag cggtgcaggt gcattgttga ttcttgctgg tctcgactat 1707241 ttatatcaga gatttgacta tgagaaaaat atcaaaatgt caaaacaaga tataaaagat 1707301 gagtacaaaa aatctgaagg agacccgatt atcaagtcta aaattaaaca aagacagcgg 1707361 gaaatggcga tgaggcggat gatgcaggaa gttccaaaag cagatgtcat tatcacaaac 1707421 ccgactcact atgcgattgc tttgaaatat gatgaagaaa aaatggacgc accttatatt 1707481 gttgcaaaag gcgtcgacca ccttgcgtta aaaatcagga aaattgctaa agagcatgat 1707541 gtcatgatgg tagaaaacag accgcttgcc cgtgcgttat atgatcaagt ggaaattgac 1707601 caggcagtgc cggaagaatt ttttaaagtt ttagcagaaa ttctggctta cgtatataaa 1707661 acaaaacaaa aagtatattg aatttttcga tttaaaagga gagaaaaaac agcatgtcaa 1707721 caagagattt atccgtttta ataagtgttg tcctcattgt ggcgatgctg gtgattccat 1707781 ttcctccatg gctgttaagt attttgatca ttattaatat ttctcttgcg ttgatcgtgc 1707841 ttctcaccac aatgaatatg caggaagcgc ttcagttttc gatttttccg tcactgttgc 1707901 tgcttttgac cctatttcgt ttgggcttga acgtctcaac tacccgttca attctttcac 1707961 acggtgaggg aggtaaagtc gtcgagactt tcggaaattt cgttgtcggc ggaaatgtat 1708021 tagttggact cgttgtattt atcatcctta ttattattca gtttatcgtc attacaaaag 1708081 gtgctgaacg tgtttccgag gttgcagcaa ggtttacgct ggacgcaatg ccggggaagc 1708141 agatgagtat tgatgctgat ttaaacgcag ggatgattac cgaacaggaa gcgaagcatc 1708201 gccgcgaaaa agtggcaaga gaagcagact tttatggagc aatggacggt gccagtaaat 1708261 ttgtaaaagg tgacgccatt gccggaatca tcattgtgat gatcaatatt attttcggaa 1708321 tcgtgatcgg aatgcttcag cagggcatgt ccattcaaga agctgcttca cactttacga 1708381 tgctgactgt aggggatgga attgtttcgc aaatcccggc actgttaatt tctacggcta 1708441 cgggtattgt ggtcacaaga gctgcatctg aaggaaactt agggcatgac attacaggcc 1708501 agctgtttgc gtatccaaag cttttatacg tcgcagcagc tacgatcatg cttttaggta 1708561 ttttcactcc gatcggcatc cttctgacgg ggccgcttgc gggattgctt gcttttggcg 1708621 catatacact atctaaatca ggtaaggaaa aagaagaagt ggatgagatt cttgaggaag 1708681 aggctgaggt ggacgagctt aaaagccctg aaagtgttgt tcagcttctg catatagatc 1708741 cgatagaatt tgagtttgga tatggcctga taccgcttgc tgatgccaat caaggcggtg 1708801 atttattaga ccgaattgtt atgatacgcc gtcagttggc tttggaactc gggcttgtca 1708861 ttcctgtcgt gcgaatcaga gataatatag cgttgcagcc taatgaatac cgattgaaaa 1708921 ttaaaggaaa cgaagtagca aaaggcgagc tgttgcttga tcattattta gcgatgtcgc 1708981 ctactcctga ggacgatctc attgaaggga ttgaaacagt ggagccttca ttcggactgc 1709041 cggctaaatg gattagcgaa gcggtaaagg atgaagccga catgcttggt tatacagtag 1709101 ttgatcctgc atcagtcgtt tcaacgcata ttacggagaa aattaagcag catgcccacg 1709161 aattgatcgg aaggcaggag acaaaacagc tgatcgatca cttgaaagaa tcgtatccag 1709221 tcctggttga agaggttacg ccgaatccat tgtctgtcgg tgatattcag aaagtgcttg 1709281 ctaagctttt aaaagaaaaa gtttcaattc gaaacttagt aacgattttt gaaacacttg 1709341 ctgactatgg gaaattaaca acagattctg atctcttgac agagtataca agacaagcgc 1709401 ttgctaaaca aattacagcc cagtttgcca aagaaaatga agtgttgaag gttgttactt 1709461 gttccggccg tgtagaaaaa gcaatagcag acggtgtgca gcagacggaa cacgggaact 1709521 atttatcact tgaaccagat atttcagaaa gtatagtgcg ctctgtcgcc aaagaagctg 1709581 aacagctctc attacgtcag gaaaccgcga ttcttctttg ctcgccgcct gtcagaatgt 1709641 atgtgaagca gctactggaa cggtacttcc ctgatcttcc ggtactctct tataacgaac 1709701 ttgaggcgaa tgttgaggta caaagcattg gagtggtgga tatttaatga aaataaaaaa 1709761 atttactgct gcttcaatgc aagaagcggc acttctcatc agaaaagagt taggtaatga 1709821 agcggtcata ttaaattcga aaaaaattaa aaagcgaaaa tggtttggcc tcgtcaacaa 1709881 gcctgctgtt gaagtaatcg ccgtattgga tcaggacttt cttgagaaaa aaacgcctca 1709941 gaaggcagct gaaccgaaac aaacattaaa aactccggtc agcagtccaa aaatagagga 1710001 gagaacatat ccccctcaaa ttccggcgca acaggagcta ggtgattttt cagcatatca 1710061 atctgtactt cctgagccgc tgcgaaaagc agaaaagctt ttgcaagaaa cagggatcaa 1710121 agagtctacg aaaacgaaca ctctgaaaaa attgcttcgc ttctctgttg aagcaggcgg 1710181 cttgactgaa gaaaatgttg tcggcaaact tcaggaaata ctatgcgata tgctgccctc 1710241 agcagacaag tggcaggagc caattcattc aaaatatatc gttctctttg gttcaacagg 1710301 ggctggtaaa acaactacac tggctaaact cgcagccata tctatgcttg aaaaacataa 1710361 aaaaatcgct tttattacaa cagatacgta tcgtattgca gctgttgaac agttgaaaac 1710421 atacgctgaa ctgctgcagg ctcctctgga agtttgctat acaaaagaag aatttcagca 1710481 ggcgaaggag ctattttctg agtatgatca tgtgtttgtt gatacagctg gaagaaactt 1710541 caaagacccg caatacattg atgaactgaa agaaacgatt ccttttgaga gcagcattca 1710601 gtcatttctt gttttatccg cgactgcaaa atatgaagat atgaagcata ttgtcaaacg 1710661 gttttcatcc gtccctgtca atcagtatat ttttacgaaa atagatgaaa cgacttcctt 1710721 aggttctgta tttaatatac tggcagaatc aaaaataggt gtcgggttta tgactaacgg 1710781 ccagaatgtg cctgaggata tacagactgt atctccactt ggttttgtga ggatgctgtg 1710841 cagatgaaca gatatgacca agcagcaact ttacgggcga aaatggaaaa acgtgagcgc 1710901 gttctgccaa tggtttattc acaaaaagcg aagacacttg ctgtcatcag cggcaagggc 1710961 ggtgtcggaa aatccaatat taccttaaat atggcacttg cgctgcagga taaaggtaag 1711021 aaggtgctgc tcatcgacct tgatatcggg atggggaaca ttgatatatt aataggaaat 1711081 tcatcgtctg ccacgataat cgatgtttta accgatcgta agcctttgct gcagtcatta 1711141 tccgttggcc caaagggttt gcggtatata tcagggggaa ccggtcttga tgtgatgttt 1711201 cagctcgatc agagaaaatg gacgtttttt gccaatgaac tttctcatgc attaagccag 1711261 ttcgattatg tgctgtttga catgggagca ggcttatcaa aagatcaact gccttttatt 1711321 ttatcagcag aagatatttt gattattaca actcccgagc cgacggccat tatggacgca 1711381 tacagcgctg tcaagcactt ggttttgaca gaaaataagc tttcaatgaa ggtggctgtc 1711441 aatcggtgcc gtgaccaaaa ggaagggctt gacgcttttg cccgcctctc ccgtacaatt 1711501 catatgtttt tggatgttca ggttcagttt gccggttccg tttctgacga tgtgatcgtg 1711561 agcaaagcgg ttgtcgaaca ggttcctttt ttcataaaaa gccctcaggc aaaagccagc 1711621 cggtcagtcc gtattttagc ggacgccttg tttgaaagag aagaaacgag acacaaagaa 1711681 gacaaacaga catttattga gaaattatct tcttttttaa tgaggagggc ttaatttgat 1711741 tcgtgtgctt gtagttgatg attcagcttt tatgagaaaa atgataagtg attttctgac 1711801 cgaagaaaag cagatagaag taatcggaac tgcgagaaac ggagaagaag cgcttaagaa 1711861 gattgaatta ttaaaaccgg atgttattac tcttgatgtt gaaatgccgg tcatgaatgg 1711921 gacagatacg ctccgcaaaa ttattgagat ttataacttg ccggtcatta tggtgtctag 1711981 ccagaccgag aaaggtaaag aatgcacaat taattgtttg gagatcggtg cctttgactt 1712041 tatcacaaag ccatcaggct caatatctct ggatctatac aaaattaaag aacaactagt 1712101 tgagcgtgtc gtcgcggcag gactttccgg caagcggaaa cgtcctgttt cccagacagt 1712161 tcggcccgaa cctattgtgc gtgctgtcgt taagcctgaa ttaagcaaac cgaaacctgg 1712221 cacgggcaga caaattgtgt gtatcggcac atcaacaggc ggtccacggg cgttacaaaa 1712281 ggtgataccg aagctcccta aggatttgaa cgcaccagtg gttgtcgttc agcacatgcc 1712341 tgaagggttt actgcttctt tggctgatcg gctgaatcat ttatctgaca ttcaggtaaa 1712401 agaagcaaaa gatggtgaag cagctcttaa cggctgtgtt tacatagcac cgggcggaaa 1712461 aaacatatcc gttattaaaa acagcgaagg actccaggtt gtgcttgata accatgacac 1712521 accaagccgt cataaaccat ctgctgatta tttattccgt tctgtcggga aactgacaga 1712581 ttatgaaaaa gtagcggtta tcatgaccgg aatgggcagt gacggcactg ctggactaaa 1712641 ggacatgcta acagccggca atgtgaaagc cattgcggag tctgaagaat cttgtgtcgt 1712701 atacgggatg ccaaaagctg ctgttaaagc gggtctcatt catgagatta aacatgtgga 1712761 agatatcgca gcatccatca caagctgtgt gaaaaaagag agggtgtgat tcaaatggat 1712821 atgaatcagt atttagatgt ctttattgat gagagtaaag aacatttaca aacatgtaat 1712881 gaaaagcttc ttcttttaga gaaagacccg actgatcttc agctcgtaca tgatatattc 1712941 agggctgccc atacattaaa aggaatgagc gcaacgatgg gctacacgga tttagcacat 1713001 cttacccatc tgcttgaaaa cgtgctggat gcaatccgaa acggagacat ggaagtcacc 1713061 tcagactggc tggatatttt gtttgaagct ctggatcacc tggaaacaat ggttcagtct 1713121 attattgatg gcggggatgg taaaagagat atctcagaag tgagtgccaa gcttgatgtg 1713181 aatggtgcgc acgctgaatc cgctgcctcc gctgaacctg cagaagcaca gagttcagca 1713241 tctgattggg aatatgatga atttgaacgc acagttatac aagaagcgga ggagcaaggc 1713301 ttcaaacgat atgaaatcaa gatttctctg aacgaaaact gtatgttaaa agcagttcgt 1713361 gtctatatgg tgtttgaaaa actaaatgaa gtcggagaag tagccaaaac aattccaagt 1713421 gctgaagtgc ttgaaacaga agattttgga actgactttc aagtttgttt cttaacacat 1713481 caatcagcgg aagacattga acaattaatc aatggcgtgt cggaaattga gcatgttgaa 1713541 gtcattcaag gggctccttt aacatcagct gaaaagcctg aagaatctaa gcaagaagat 1713601 tcaccagcag cagctgtacc tgcgaagcag gagaaacaaa aacagcctgc taaaaacgat 1713661 gaacaggcga agcattcagc cggcggatct aaaacaattc gtgtcaacat tgacaggctt 1713721 gattctttaa tgaacttatt tgaagagctt gtcattgacc gcgggcgtct cgagcagatt 1713781 gcgaaagagc ttgagcataa tgaactgact gaaacggttg aacgaatgac gagaatttcc 1713841 ggagatttgc aatcgattat tctgaatatg agaatggtcc cggttgaaac tgtttttaac 1713901 agattcccga gaatgattcg ccagcttcag aaagagctga ataaaaaaat tgaactctcg 1713961 atcatcggtg cggaaactga actggatcgt acagtaattg atgaaatcgg agatccactc 1714021 gttcacttga tcagaaacag tattgaccat ggtatcgagg cgccggaaac acgtttgcaa 1714081 aagggaaaac cggaatcagg aaaagttgtg cttaaagctt atcacagcgg caaccatgtc 1714141 tttatcgaag tagaggatga cggcgcaggc cttaatcgaa aaaaaattct ggaaaaagcg 1714201 cttgagcgcg gggtcataac ggaaaaagaa gctgaaacct tagaagacaa ccaaatttac 1714261 gaattgattt ttgctccggg gttctcaact gctgaccaaa tttctgatat ttccggccgc 1714321 ggtgtaggac ttgacgttgt aaaaaacaaa ctggagtctc ttggcggttc agtcagtgtg 1714381 aaatcagccg agggtcaagg ctctctattc agcatccagc tgccgcttac cttgtctatt 1714441 atttcagttc tgctgattaa gttggaagaa gagacatttg ccattccgat ttcttcaatc 1714501 attgagacag cagttattga cagaaaagac attttgcaaa cgcatgaccg tgaagtgatt 1714561 gactttagag ggcatattgt ccctgtcgtt tatttaaaag aagagtttaa aatagaagat 1714621 acaagaaaag atgcggaaca gctccatatc attgtcgtga aaaaaggcga caaacctact 1714681 gcatttgtgg tggactcctt tattggccag caggaagttg tgctgaaatc actcggagat 1714741 tatttaacaa acgtctttgc aatttccgga gctactattt taggagacgg agaagtagcg 1714801 ctcattattg attgtaatgc actgattatt taaccattcg aggaggtgtc tcacatgact 1714861 gcagaaatta aaacaggcga aaaaatgata gtctttatgg taaatggcaa agaatatgcc 1714921 atttccgtca ctcaggtgaa atcaattgaa aaatggcaaa agccaacgag ggtacctggc 1714981 gtcgaaccat atatttgcgg ggtaatcaat ttacgcgggg tggtgactcc ggttattgat 1715041 ttaagaaaac gcctgaattt gccagagtat gaaattacag atgaaacacg aattatcatt 1715101 attgcttatc gtgatattga agtcggctgg attgtggatg aagcgaatga tgtgattacc 1715161 gtacacgaaa gtgaaataga atctgctcca gaaggcgttc agaaagatac ggatgtgtcg 1715221 atcgaacaga ttgtgaaaca agagaacaga ctcttaaata ttattgatgc gaacgcggtt 1715281 ttggataaag aatcatctca gtccgctgtg cccgatcaag cttaatctta aaggggttat 1715341 gacatgagta tttttaatgg aatcaaagaa gagcagatgg acattttgcg ggaagtcggc 1715401 aatataggcg ccggccactc cgcctctgca atggcccagc tgttaaatag aaagatagat 1715461 atggaagtcc catttgcaaa gctgctgtct tttgatgagc ttgttgattt tttcggcggc 1715521 gccgatgtcc cggttgccag catcttttta agaatggaag gcgatttaac gggttcaatg 1715581 ttctttataa tgcctttttt tcaggcggag cagtttatca gagagctgat tggaaacccc 1715641 gattttgaca tagaggactt aggtgaagac cacatgagct catccgcttt gcatgaactg 1715701 ggcaatattt tagcggggtc atatttaaca gctttggcgg atttgacgaa actccagctc 1715761 tatccaagtg ttcctgaagt ctcattggac atgttcggag ctgtgatcag cgaagggctg 1715821 atggagctca gtcaggttgg agaacacgcc attgttgtcg acacgtcaat ttttgaccaa 1715881 agccatcagc aggagctgaa agcgcatatg tttatgctgc cggactatga ttcatttgaa 1715941 aagctctttg tcgccttagg tgcatcatta tgagtacaac tgaggctgtt gttataaagg 1716001 ttgggattgc tgacgtgaag atcgcccgct tcccggatac catccggacc tctggtttgg 1716061 gctcatgtgt ggggctggtg ctttatgata aagaaaagca aacggcgggt cttgttcatg 1716121 tcatgcttcc ggattcgacg ttatcgaaaa ctgccgagct caaccgggct aagtacgctg 1716181 acaccgccgt acagaccacg attgatatgc tgatagaagc gggatgccgg aaatttgcat 1716241 taaaagcaaa gctggccggc ggatcagaga tgtttaaatt taaatcgaca aatgatttga 1716301 tgaagatcgg accgagaaat gtattagcga taaaagaaca gctgtcttta tttaatattc 1716361 ctattattag tgaagatacg ggcggctcaa gcggccggac gatagaattt gaaccgaagt 1716421 cctgcatgct gcatattcga actgttaaac aaggtgaaaa aacgatttaa ttaaggtatt 1716481 agggggataa caatgcaatc cttgaattat gaagatcagg tgctttggac gcgctggaaa 1716541 gagtggaaag atcctaaagc cggtgacgac ttaatgcgcc gttacatgcc gcttgtcaca 1716601 tatcatgtag gcagaatttc tgtcggactg ccgaaatcag tgcataaaga cgatcttatg 1716661 agccttggta tgcttggttt atatgatgcc cttgaaaaat ttgaccccag ccgggactta 1716721 aaatttgata cctacgcctc gtttagaatt cgcggcgcaa tcatagacgg gcttcgtaaa 1716781 gaagattggc tgcccagaac ctcgcgcgaa aaaacaaaaa aggttgaagc agcaattgaa 1716841 aagcttgaac agcggtatct tcggaatgta tcgcccgcgg aaattgcaga ggaactcgga 1716901 atgacggtac aggatgtcgt gtcaacaatg aatgaaggtt tttttgcaaa tctgctgtca 1716961 attgatgaaa agctccatga tcaagatgac ggggaaaaca ttcaagtcat gatcagagat 1717021 gacaaaaatg ttccgcctga agaaaagatt atgaaggatg aactgattgc acagcttgcg 1717081 gaaaaaattc acgaactctc tgaaaaagaa cagctggttg tcagtttgtt ctacaaagag 1717141 gagttgacac tgacagaaat cggacaagta ttaaatcttt ctacgtcccg catatctcag 1717201 atccattcaa aggcattatt taaattaaag aatctgctgg aaaaagtgat acaataatga 1717261 atttcatggt tagcgagtga aaaacatgtc aacactatta tggcttttaa gctttatgct 1717321 ccacggcgtt cttctgtacg ctgtcattat cctgtatacg aggctcgctg cagtgaaaga 1717381 aacagaaaaa cagcaaaaac agatacttga agagacggaa aacaccttgg cggcatttct 1717441 gcttgaatta aaagaagaaa atgagaaact gatagaaaat aaagcttcat ctgcaagtca 1717501 atcagatgaa gaatcccaaa agtcaggcct tcagacctct gaaacatatc aagagcggga 1717561 tccagtccaa gaggcagaga atcttcctga acatattgaa ggtctgatta cagaggttga 1717621 ccgtcgggaa gagctcgtaa acagtgaggt ccaatcattt gaagaccagg tcatagaatt 1717681 atatgaacag ggatattcgg caagtcaaat tgcccagaaa atgaagagcg gaaagacaga 1717741 aatcgagcta tttttaaaat ttcgctccaa aggtgtaaag gattcttgat tgtcggataa 1717801 agctgtgtta tattatgtct tggtgttaaa tacacacgct taacgattta tgcagagggt 1717861 gctgcaggcg gcagttctgt acaaaaatga cctaagcgga ggaaaaaaac cattatatta 1717921 ggaggaaata acatgtcagt catttctatg aagcaattgc ttgaagctgg tgttcacttc 1717981 ggtcaccaaa cacgccgttg gaacccaaaa atgaagcgtt acattttcac ggagcgtaac 1718041 ggaatctaca tcattgacct tcaaaaaaca gtcaaaaaag tagaggaagc ttacaacttc 1718101 actaaaaatc ttgctgctga aggcggaaaa atccttttcg tcggaacaaa aaaacaagct 1718161 caagattctg ttaaagaaga agctcaacgc tctggcatgt actatgtcaa ccaacgctgg 1718221 ttgggcggta cattaacaaa cttcgaaaca atccaaaaac gtattaaacg tcttaaagac 1718281 attgaaaaaa tgcaagaaaa cggtacgttt gatgtacttc ctaaaaaaga agtcgttcaa 1718341 ttgaaaaaag aattagagcg tcttgaaaaa ttcctaggcg gaattaaaga tatgaaggat 1718401 cttcctgatg cattattcat catcgatcct cgcaaagagc gcatcgctgt tgcggaagct 1718461 cgcaaattaa acatccctat catcggtatc gtagatacta actgtgatcc agatgaaatc 1718521 gatgttgtta tcccagcgaa cgatgacgct atccgcgctg ttaaacttct aacttctaaa 1718581 atggcagatg caatcttaga agcgaagcaa ggcgaagaag aagcggaagt tgctgaagaa 1718641 actgcaccag aaacagaaac aacaactgcg taacctattc aaaaggtgat aagagggact 1718701 gccttttatc accttttttc aagaaaaatg tgtaatatac atactcttgt ttaaacatat 1718761 aaggaggaat acaaatggca attactgcac agcaagtaaa agaactgcgt gaaaaaactg 1718821 gcgcgggcat gatggattgt aaaaaagcgt taactgaaac tgacggagat atggacaaag 1718881 caattgacct tttaagagaa aaaggaattg caaaagcagc gaaaaaagct gaccgtatcg 1718941 cagcagaagg ttctactctt attaaaactg acggcaacaa aggcgttatc ctagaagtaa 1719001 actctgaaac tgatttcgtt gcgaaaaacg aaggttttaa agagcttctt aacactttag 1719061 ctgaccacct tcttgcaaac acgccagctg atgttgaaga agcaatgggc caaaaaatgg 1719121 aaaatggctc aactgttgaa gagtacatca caagcgcagt tgctaaaatc ggtgagaaaa 1719181 tcactcttcg ccgctttaca gttcttacaa aagacgacag ctctgcattc ggtgcgtacc 1719241 ttcacatggg cggccgcatc ggtgtattaa ctgttctcaa cggtacaact gatgaagaaa 1719301 ctgcgaaaga tatcgcaatg cacgttgctg cagttaaccc tcgttacatt tctcgtgatc 1719361 aagtatctga agaagaaaca aatcatgagc gtcaaatctt aactcagcaa gccctccaag 1719421 aaggcaaacc tgaaaacatc gtagcgaaaa tggttgaagg ccgtctgaac aaattcttcg 1719481 aagaaatttg tctattagac caagcgttcg ttaaaaaccc agatgaaaaa gtgaaacaag 1719541 ttattgcagc gaaaaacgct actgttcaaa cttttgtccg ctatgaagtt ggagaaggca 1719601 tcgaaaaacg tcaagaaaac tttgctgaag aagtaatgaa ccaagtgaaa aaataatggt 1719661 gaaaagattt cgcggctaag tcgcgtcttt tcaggcagta taggggacac attttgtgtt 1719721 ccctattttt aaaactatat ttacaaacct ttttttctct tgcataatag aaaacggcaa 1719781 tgtttacact tggaggttat catggaaaaa ccaaaataca aacgtatcgt attaaagctt 1719841 agcggggaag cattggcagg agaacaggga aatggaatta acccgactgt cattcaatcc 1719901 attgcaaagc aagtgaagga aatcgctgag cttgaagtcg aagtggctgt tgttgtaggc 1719961 ggcggcaact tatggcgcgg aaaaacagga agtgacctgg gcatggaccg cgcgactgct 1720021 gactatatgg gaatgctggc gacagtaatg aattcgcttg ctcttcaaga cagcttggaa 1720081 acactcggaa tccagtccag agtgcaaaca tccattgaaa tgagacaagt tgctgaaccg 1720141 tacataagaa gaaaagcgat acgccactta gagaaaaaac gtgtcgttat tttcgctgcg 1720201 ggcacaggaa acccatattt ctcaactgat acgacagctg cactgcgggc tgctgaaatt 1720261 gaggcagacg ttattttaat ggctaaaaat aacgttgacg gtgtgtataa tgctgatcct 1720321 agaaaagatg aatcagctgt taagtatgaa tcactttctt atcttgacgt tcttaaagac 1720381 ggcctggaag tcatggattc aacagcttcc tctttatgca tggacaatga cattccgctt 1720441 atcgtctttt ctattatgga agaaggaaat atcaaacgtg ccgttatcgg tgaatcaatc 1720501 ggaacgatcg tgagggggaa ataacgtgtc aaaagaagta ttaactcaaa caaaagaaaa 1720561 aatggaaaaa gcaattgctg cttatcagcg cgaattggct actgtacgcg caggccgtgc 1720621 aaatccatca ttattagata aagtaacggt tgaatattac ggagcgcaga cacctttaaa 1720681 tcagttgtct tctattaacg tgcctgaagc tcgtatgctc gttatcacgc catacgataa 1720741 aacagcaatc ggtgatatcg aaaaagcgat tttaaaagct gatttaggtc ttacaccaac 1720801 aagtgacggc aatatgattc gaattgcaat tccggcacta acagaagaga gacggaaaga 1720861 attagtgaaa gttgtaaaaa aatatgctga agaagcaaaa gtagctgttc gtaacgttcg 1720921 ccgtgatgct aacgatgatc tcaaaaaact tgagaaaaac ggagacatta ctgaggatga 1720981 actgcgtgct tccactgaag acgttcaaaa actgacagat gaatatgtgt caaaaattga 1721041 cagtgtcaca aaagacaaag aaaaagaaat catggaagtt taatgaaaaa ctatgtacaa 1721101 tagataatag tgaaaagacc ctctcatgtt tacagggggt ttttttgtta atactgttga 1721161 ttacattgat tatcagcagg gaatgtaacc tttttgggtg acggaggaat ctcatgctca 1721221 acatactcaa aaattggaag aatcagcaaa ctgcggcttc caacttagaa cgttatacaa 1721281 aagaagacat acttaaggga gaaattcccg aacacatcgc cattatcatg gatggaaatg 1721341 gccgttgggc taaaaaacgc tctcttccca gaattgcagg ccaccatgaa gggatgaagg 1721401 tggtaaaaag gaccacgaag ctcgcaaacg aattaggtgt caaagtactg acattgtatg 1721461 cattttcaac agaaaactgg aaaagaccga aaatggaggt cgatttttta atgaagcttc 1721521 cggaagaatt tttgaatacg tatcttccag agcttgttga ggaaaatgta caggttcgga 1721581 tcattgggga tgaaacggct ttgccggcgc acacattacg tgcgattgaa aaagctgtac 1721641 aggacacggc gcaaaacgac ggaatgatcc ttaattttgc tcttaactat ggaggccgta 1721701 ctgaaattgt cagtgctgca aaatcactcg cggaaaaagt gaaggaaggc tctttgaata 1721761 ttgaagacat tgatgaatcg cttttttcta cttatttgat gactgaatct ttgcaggatc 1721821 ctgaactttt aattcgaacg agcggcgaga taaggctgag taattttatg ctatggcagg 1721881 ttgcctacag tgaatttgtc tttactgacg tcttgtggcc tgactttaaa gaagatcact 1721941 tcttgcaggc gttaggagag tttcagcaga gaggccggag gtttggcgga atttagagga 1722001 tggtggacat gaaacaaaga attttgacag gtgttctggc agcaattgta tttttatttt 1722061 tggttattgt cgggaaattg ccgttcacca tattaattta tgctatgggc agtgtggcgc 1722121 tttttgaact tttacggatg aaaaagctga agctggtttc actgccgggt ttgatcggtc 1722181 ttttattatt gtggatgttc ttattaccaa gccagtattc gttttttgaa gcggacggga 1722241 tttccaaaat ggaaatcgct ttatttgcgg tactgctatt gctgacttac acagtgttgg 1722301 tcaagaacac ctttactttt gatgaagtcg ggtttattac gcttgcagca atttacatcg 1722361 gaatgtgttt tcattatttt atcgaaatca gaaatcttga ccaatacgga ttaacataca 1722421 ttttttatgc gtgtgttgtc atttggtcca ccgattccgg tgcctatttt gtcggtaaat 1722481 cgcttgggaa gcggaaactg tggcctgaaa tcagtccgaa taaaacagtg gaagggtttg 1722541 caggcggaat tgtcatcgca cttgtattgg cgacgatttt tcagcttgtt gcacaacttc 1722601 cgatcccgta tatctatctg ctgttgatca cgctgttttt gtctgttttt ggacaactgg 1722661 gagatttagt ggaatccgcc ttgaaaagac attacgatgt aaaggattct gggaatattc 1722721 ttcccgggca tggcggtata ttagaccgtt ttgacagttt cttgtttgtc atgcctttct 1722781 tgtactttct gcttgccctt ttttcataaa aaagtctaat atgaatatga gactgatcat 1722841 gcagcaataa gaataggagt agtggcaact ttgaaaaata tttgtctttt aggagcaaca 1722901 ggatcaatcg gcgaacagac tcttgatgta ctgcgtgcac atcaagacca atttcagctg 1722961 gtatctatgt cgtttggcag aaatattgat aaggccgttc caatgattga ggtctttcag 1723021 ccgaagtttg tctctgtcgg tgatctggat acatatcata aattaaaaca aatgtctttt 1723081 tcttttgaat gccaaatcgg gctgggagaa gaaggactga tagaagcagc agtgatggag 1723141 gaggttgaca ttgttgtcaa cgctttgctt ggaagcgtcg gtcttatccc gacattaaag 1723201 gcaattgaac agaaaaaaac aattgcgctt gcaaataagg aaactcttgt cactgcaggg 1723261 catatagtaa aagaacatgc taagaaatat gatgttccgc tgctgcctgt tgacagtgag 1723321 cattcagcca tttttcaagc tcttcaaggc gaacaggcta aaaacattga acgcctcatc 1723381 attacggcat ccggcggaag ttttcgggac aagacgcggg aggagctcga atcagtaacg 1723441 gttgaagatg cattaaaaca tccaaactgg tcaatgggtg caaaaattac aattgattcg 1723501 gctacaatga tgaataaggg attagaggtg atcgaggcac actggctttt cgatatacct 1723561 tatgaacaaa ttgatgtggt tttacataag gagagcatca tccattcaat ggttgagttc 1723621 catgataaaa gtgtgatcgc acagctcgga actccggata tgagagtccc cattcaatat 1723681 gcgctcactt atcctgaccg attgccatta ccagatgcga aaaggcttga attatgggaa 1723741 atcggcagcc ttcattttga gaaagctgat tttgacaggt tccgatgctt acaatttgct 1723801 tttgaatcag gtaaaatagg aggaacaatg ccgacagtgc taaatgcggc aaacgaagta 1723861 gctgtcgctg cctttttagc tggcaagata ccgtttttgg ctattgaaga ctgtatcgaa 1723921 aaggcactaa cccgccatca attactgaaa aaaccgagcc tggcggacat tcaagaagtg 1723981 gacaaagata cccggggata cgtcaattca atactcacat aaggtggtat gttcgtgaat 1724041 acagttatag cgtttatcat tattttcgga acgctcgttt tcttccatga actgggccat 1724101 ttattgctag cccaaagagc gggaattctc tgccgtgaat ttgcgatcgg cttcggtcca 1724161 aagatttttt ctttcaaaaa aaatgaaaca gtttatacga tcaggctgct tccggtcggc 1724221 ggatttgttc gtatggccgg cgaagatccg gaaatgattg aggtgaaacc cggatacacg 1724281 gtcgggcttc tgtttaataa ggaagatcaa gttgagaaag tcatcatcaa tcaaaaggaa 1724341 aaatatccgg atgctttagt cattgaagtg gaaacagcgg atctagagca tgacatgaag 1724401 atcaccggtt atgaacaggg gaaagaggac gaactttcca gctttactgt cagcgaaaca 1724461 tcctttttta ttgtagacgg agaagaagtg cagattgcgc cgtataatcg ccaatttggt 1724521 tccaaacctg tatggcagcg gattaaagca attgctgcag ggccgattat gaactttatt 1724581 ttagcttacg tcattttagt gatgcttggg ctgattcaag gcgtaccgtc aaatgaacct 1724641 atgctcgggc agctgacaga caatggacgg gcggctgaag cagggctaaa agaaggggat 1724701 tatatccaaa gcattaacgg agagaaaatg aggtcttgga ctgacattgt ctccgctgta 1724761 aaagaaaacc cggagaaaga aatggacgtt gcagtaaaaa gagataacaa aacgcttcat 1724821 atttcggtga ctccggaagc tgttaaagat gagaacaaaa aaacaatcgg acgtttcggt 1724881 tcctatgcgc cgactgaaaa aggcgtactc tcagcggttg cttacggcgc gacatcaaca 1724941 gttgatgtca ccaaagccat tttaaccaat ctgagcaaat tagtaacagg ccaatttaaa 1725001 ctcgatatgc tgtcaggtcc tgtcggcata tatgacatga cagaccaagt ggcgaaaaca 1725061 gggatcgtga acttatttca gtttgcggcg tttttaagca ttaaccttgg gattgtcaac 1725121 ctgcttccga ttccggcact tgacggagga agactgttgt ttctatttat tgaagcgatt 1725181 cggggcaaac cgattaacag ggaaaaagaa gcatttgttg tgtttatcgg agtagctttc 1725241 ttaatgcttc ttatgctggt tgtcacatgg aacgatatcc agcggctgtt tttgtaaacg 1725301 aaaagtaaat caatcagagg tgcgaagaaa tgagacaaag cttgacgctt attcctacgc 1725361 tccgtgaagt tccagctgat gccgaagcaa aaagtcatca gcttcttctg agagcaggat 1725421 ttatcagaca gaatacgagc ggggtataca gctatatgcc tcttgcgtat aaggtgattc 1725481 aaaacattca gcagattgtt cgagaggaaa tggagaaaat tgatgccgta gaaatgctca 1725541 tgcccgcatt gcagcaggca gagacatggc aggaatcagg cagatggtat acgtatggtc 1725601 ccgaactgat gagactaaaa gaccgtcatg gccgtgaatt tgctttaggg gcaacgcatg 1725661 aagaggttat cacttcgctt gttcgcgatg aggttaaatc ttataagcgt ctccctctga 1725721 ctctttatca aattcagtct aagttcagag atgaaaaacg tcctcgcttc ggtttgttaa 1725781 gaggccgcga atttattatg aaggatgcgt actctttcca tgcatctgca gagagcctgg 1725841 atgaaacgta tcaaaaaatg tacgaggcct attctaatat ttttgcccgc tgcggcatta 1725901 atgtaagacc tgttatcgct gattcaggcg caatgggagg aaaggatacg cacgaattta 1725961 tggcactttc tgcgatcgga gaggatacga ttgcgtattc tgatgaatca cagtacgcgg 1726021 ctaatatcga gatggctgaa gttcttcacc aggaagttcc ttcagatgaa gagcctaaag 1726081 ctctagagaa ggttcatacg cctaacgtga aaacaatcga agaactgact gcgttcttac 1726141 aggtttcggc tgaagcgtgc attaagtcag tattgtttaa agctgatgac cgttttgtct 1726201 tagtgcttgt aagaggggat catgaagtta acgatattaa agtgaaaaac ttgcttcatg 1726261 cagaagttgt agagcttgct acacatgaag aggtcattca gcagctcgga acagagccag 1726321 gctttgtagg ccctgtcggt attcatcagg atgtggaagt atatgccgat caagctgtga 1726381 aagcaatggt taatgctgtt gccggggcaa atgaaggaga tcatcattat aaaaatgtca 1726441 atgtgaatcg tgacgcgcaa attaaagaat ttgctgatct tcgttttatt aaagaaggtg 1726501 atccttcacc agacggcaag ggaacgatcc gttttgctga gggaatcgaa gtcggacaag 1726561 tctttaagct cggaacacgc tattcagaag cgatgaatgc gacatattta gatgaaaacg 1726621 gacgcgcgca gccaatgctg atgggctgtt acggaatcgg tgtgtcaaga acgctttctg 1726681 ctattgctga acagcatcac gacgaaaaag gcttaatatg gccaaaaagc gttgcgccgt 1726741 acgatcttca tattcttgct ttgaacatga aaaacgatgg gcaaagagag cttgctgaaa 1726801 agctgtatgc cgatttaaaa gcggaaggct atgaagtgct ctatgatgac cgtgctgagc 1726861 gtgccggcgt aaaattcgct gattcagatt taatcggcct tccaatccgc atcactgtcg 1726921 gaaaacgagc tgacgaagga atcgtcgaag tgaaaattcg tcaaactggt gagtcaactg 1726981 agatttcagt agacgaatta tctgcgttta tcagcaagca gtaatcacca taacgattta 1727041 tcaaaaaaca tgttaaaata gaaataatag aaggtacctc attgcctgag gtaccttcac 1727101 ttatgatgtt tttagggagg gatactgtct taatggaaca gttatcagta aacagaaggc 1727161 agtttcaaat tcttctgcag cagattaata tgacagatga taccttcatg acatactttg 1727221 aacatggcga gattaaaaag ctgacaattc acaaagcttc taagtcttgg cattttcatt 1727281 ttcaatttaa atctttgctg ccttttcaaa tatatgacac attaacaacg aggctgacgc 1727341 aatcgtttgc ccacatagca aaagtgacat cttcaattga agttcaggat gccgaggtca 1727401 gtgaaagtat cgttcaagac tactggtcac gctgcattga agaactgcag ggcatttcgc 1727461 cgccgattat cagtctttta aaccagcaaa aaccgaagct gaagggcaat aaactgattg 1727521 tcaaaaccaa aacagataca gaagcggctg cgctaaagaa caaatacagt tccatgattc 1727581 aagcagaata ccgtcaattt ggctttccgg atcttcagct tgatgctgaa atatttgtat 1727641 ccgagcaaga agttcaaaag tttcgggagc aaaagcttgc ggaagaccaa gagcgggcta 1727701 tgcaggcctt gattgaaatg gagaagaaag ataaagaaag tgatgaagac caagcaccat 1727761 ctggtcctct tgttatcggt tatcaaatta aagataacga ggaaatccga acacttgaca 1727821 gcatcatgga cgaagaacgg agaattacgg tccaaggtta tgtgtttgat gtggagacgc 1727881 gcgagctgaa gagcgggcgc acgctgtgta tcttcaaaat tacagactat acaaatagta 1727941 ttttgatcaa aatgtttgca cgtgaaaaag aagatgcggc gctgatgaag tctctgaaaa 1728001 aaggaatgtg ggtaaaagca cgcggaagca ttcaaaatga tacatttgtc agagaccttg 1728061 tcatgatcgc aaatgacgta aacgaaataa aagcaaaaac ccgtgaagat tcagcacctg 1728121 aaggagaaaa aagagtggaa ttgcatcttc attccccaat gagccaaatg gatgctgtta 1728181 cgggtatcgg aaagcttgtc gaacaggcga aaaaatgggg gcatgaggcc atcgctttga 1728241 ccgaccatgc tgtcgttcaa tccttccctg atgcgtattc tgcggccaaa aagcatggaa 1728301 ttaaaatgat ttacgggatg gaagcgaatc tcgtggatga tggcgtgcca attgcttata 1728361 atgccgcaca tcgtctgctc gaagaagaaa catatgttgt ttttgacgtt gagacgacag 1728421 gattgtctgc tgtatacgat accattattg agctggctgc agtaaaagta aaaggcggag 1728481 aaattattga taaatttgag gcgtttgcga acccgcatcg tccgctttcc gccacaatca 1728541 tagagctgac agggatcaca gatgatatgc tacaagacgc tccggatgtc gtagatgtaa 1728601 taagagattt cagagaatgg attggcgatg atattcttgt cgctcataat gcaagctttg 1728661 atatgggatt cttaaatgta gcctataaaa aacttcttga agtcgaaaaa gctaaaaacc 1728721 cagtcattga tacgcttgaa cttggacgtt ttctctatcc ggaatttaag aaccaccggt 1728781 tgaacacact ttgtaaaaag tttgatatcg agctcacaca gcatcaccgt gcgatctatg 1728841 atactgaggc aaccgcttat ttgcttctga aaatgctgaa agacgcagct gaaaaaggta 1728901 ttcagtacca tgatgagttg aatgaaaata tgggtcagtc caatgcttat caaagatcaa 1728961 gaccgtatca tgcaacatta cttgccgtga acagcacggg acttaaaaat ttatttaagc 1729021 ttgtgtcact ttctcatatt cattattttt acagagtgcc gcgtattccg agatctcagc 1729081 ttgagaaata cagggaaggg cttctgatcg gttctgcttg tgacagggga gaggtttttg 1729141 agggaatgat gcaaaaatcg cctgaagagg tggaagatat cgcgtcattc tatgattacc 1729201 ttgaggttca gccgcctgaa gtgtatcgtc acttgctgga gcttgaactg gtccgtgatg 1729261 aaaaagcgct gaaagaaatt attgcgaata tcacgaagct gggggaaaag cttaataaac 1729321 cggttgttgc tacgggaaat gttcattact tgaatgatga ggataaaatc tacagaaaga 1729381 ttttaatatc ctcacaaggc ggggcaaatc cgctgaatag gcatgaactg ccgaaagtgc 1729441 atttcagaac gacagacgaa atgcttgaag ctttttcttt cttaggtgaa gaaaaagcga 1729501 aggagatcgt agtcaccaat acccaaaagg ttgcttcttt agttgatgac atcaagccga 1729561 ttaaagatga tttatatacg ccgaaaatcg aaggcgctga tgaagagatc agagaaatga 1729621 gctatcagcg tgcaagaagc atttacgggg aagagctgcc tgaaattgtc gaagcgcgga 1729681 ttgaaaaaga gttaaagagt attattggcc acggatttgc tgttatttac ttgatctctc 1729741 acaaacttgt aaaacgttca ctagatgacg ggtatctcgt tggttcccgt ggttccgtag 1729801 gatcttcatt agttgcgaca cttactgaga ttactgaggt aaacccgctg ccgccgcact 1729861 atgtttgtcc tgagtgccag cattctgagt tctttaatga cggttctgtc ggttctggtt 1729921 ttgacctgcc tgacaagaca tgccctcatt gcggaacgcc tttgaaaaaa gacggccatg 1729981 atattccatt tgaaacgttc ttaggattta aaggggacaa agtacctgat atcgatttga 1730041 acttctcagg ggaatatcag ccgcaagcac acaattacac aaaagtattg ttcggagaag 1730101 acaatgtata tcgtgcggga acaataggca cggtggcaga aaaaacagcc tacggttatg 1730161 taaaaggcta tgccggagac aacaatcttc atatgcgcgg tgccgaaata gatcggctcg 1730221 tacagggatg cacaggtgta aaacgtacaa ctggacagca ccctggcggt attatcgtag 1730281 ttccggatta tatggatatt tatgattttt caccgatcca gttcccggca gatgccacag 1730341 gttcagagtg gaaaacgact cattttgatt tccactccat ccatgacaac ctgttaaaac 1730401 ttgatattct cggacacgat gacccgactg ttattcggat gcttcaagac ttaagcggaa 1730461 tagatccgaa aacaattccg acggatgatc ctgaagtgat gaagatcttc cagggaaccg 1730521 aatcactcgg tgtgactgaa gaacagattg gctgtaaaac gggcactctt ggaattcctg 1730581 aattcggaac ccgatttgtc cggcagatgc ttgaagatac aaagccgacc actttttctg 1730641 agctcgttca gatttcaggc ttgtctcacg gaactgatgt atggcttggc aatgcacagg 1730701 agctcatcca caataatatt tgtgagctga gtgaggttat cggctgccgt gatgacatta 1730761 tggtttattt aatctatcaa ggccttgagc cgtcccttgc ctttaaaatc atggaattcg 1730821 tgcgtaaagg aaaaggatta acgcctgaat gggaagaaga aatgaaaaat aacaatgtcc 1730881 cagactggta tattgattcc tgtaaaaaga ttaaatacat gttcccgaaa gcccacgccg 1730941 cggcatatgt cttaatggca gtccgcattg cttactttaa agtgcatcat gctcttttgt 1731001 attatgcggc ttattttacc gttcgtgcag atgactttga tattgataca atgatcaagg 1731061 gctctacagc aatcagagcg gtaatggagg atataaacgc taaaggactt gatgcttcac 1731121 cgaaggaaaa gaaccttctg actgttttag aattagcgct tgagatgtgt gagagaggct 1731181 attcattcca aaaagtcgat ttatatcgct ccagcgccac agagtttatt attgacggca 1731241 acagtcttat tccgccgttt aactctattc cagggttagg gacgaacgct gctttgaaca 1731301 ttgtaaaagc tcgcgaagaa ggcgaattcc tctcaaaaga agatttgcaa aagagaggga 1731361 aagtatcaaa aacgatttta gagtacttag atcgccatgg ctgtctggag tcactgcctg 1731421 atcaaaacca attgtcactg ttctaatatg gaaagcagaa tttctcagaa attctgcttc 1731481 tatgcataca taagcgcaaa aagtgccatc gtaatattag agtttctgtc acttgcttag 1731541 gtatgaaggt aagcgtatat ccatttgcaa taaaaatatg gttatggtat agttttattg 1731601 gaaatgctaa cgattaccga ggcaaagagt ggggaaaccc gctcttttgt attgaacagg 1731661 agaattttgt ctcgacatgt tcatcgttta ctttttagcc cctgctcttt tgaagcaggg 1731721 tttttatgca gagtgacgag acgaatatga gatcgacagc acaaggagga agaacatgag 1731781 caaaaaagtg actgacaccg ttcaagaaat ggctcagcca atcgtagaca gccttcagct 1731841 ggaactcgtt gacattgaat ttgtcaaaga gggccaaagc tggttccttc gcgtgtttat 1731901 tgattccgat gacggtgtgg atattgagga atgtgccaaa gtaagcgaag ctttaagcga 1731961 aaagcttgat gaggcagacc caatcagcca aaattacttt cttgaagtct catctccagg 1732021 agctgagcgt ccgctaaaga aaaaagccga tttcgaaaaa tcactaggaa aaaacgtata 1732081 cattaagacg tatgagccta ttgacggcgt aaaagtgttt gaaggtgaac tggctgaatt 1732141 tgatggacaa acagtgacag ttgagatcac gatcaaaaca agaaagaaac ggatcaatat 1732201 tccgtatgaa aagatagcta atgcaagatt agctgttaca ttctaatgaa tacaaatgtt 1732261 ttaagggggg agaccgttaa atgagcagtg aattattaga tgctctcacg attcttgaaa 1732321 aagaaaaagg catcagtaaa gaaattatca tcgaagcaat cgaagctgcg ttaatttctg 1732381 cttataagcg gaattttaat caagcgcaaa atgtacgggt ggatctaaac cgtgaaactg 1732441 gctccatccg tgtatttgca agaaaagatg tcgttgacga agtatacgac cagagattag 1732501 aaatctcaat tgaagaggca cagggcatcc atccggaata tatggtcggc gatgtcgtcg 1732561 aaatcgaagt tacacctaag gatttcgggc gcatagctgc tcaaacagcg aagcaggtcg 1732621 tcacacagcg tgtgcgcgaa gctgagcgcg gtgtgattta ttctgaattt atcgaccgtg 1732681 aagaagacat catgacaggg atcgtccagc gtctggacaa taaatttatc tacgtgtctt 1732741 taggcaaaat agaagccttg ctgccggtta atgagcaaat gccgaatgaa agctacaagc 1732801 cccatgaccg cattaaggta tatatcacaa aagtagaaaa aacaacgaag ggtccgcaga 1732861 tttatgtgtc aagaacacat ccaggcctgt taaagcgttt gtttgaaatt gaagtgcctg 1732921 aaatttatga tggaactgtc gagctaaaat ctgttgccag agaagccggc gaccgttcga 1732981 aaatttctgt tcgcacagat gatcctgacg ttgatcctgt cggttcatgc gtagggccta 1733041 aaggccagcg tgtgcaagca atcgtcaatg aattaaaagg tgaaaaaatt gacattgtca 1733101 actggtccag tgatcctgta gaatttgtcg cgaatgcgct cagcccttcc aaagtgcttg 1733161 atgtcattgt taatgaagaa gaaaaagcga caactgttat tgttcctgat taccagctgt 1733221 ctctggcaat tggaaaaaga ggacaaaacg cacgcttagc tgctaaactg acaggctgga 1733281 agattgatat taagagcgaa acggacgcaa gagaacttgg aatctatccg agagaacttg 1733341 aagaagatga tgagccgctc tttacggagc ctgaaactgc tgaatcggat gaataagagg 1733401 tgactttagg tgaataaaca caaaaagatc ccattacgca aatgtgtagt gactggtgaa 1733461 atgaagccta aaaaggaact gatccgagtt gtacggtcga aagaaggcga aatctcagta 1733521 gacccgaccg gaaaaaagaa tgggcggggt gcttatttaa cgctggataa agagtgcatc 1733581 ttagcagcaa aaaagaaaaa cactttgcaa aatcaatttc aatcacaaat cgatgaccag 1733641 attttcgatg aattgctgga actggcggaa aaggtgaaaa aataaaatgt ctggaatgga 1733701 atggtttccc ttgctgggtc tggccaatcg agctcgtaag gtcgtgtcag gcgaagactt 1733761 ggtaataaaa gaaatcagga atgcgcgtgc aaagcttgtc ctgcttacag aggatgcatc 1733821 atctaacaca gcaaaaaaag taactgacaa gtgcaattat tataaagtcc cttataaaaa 1733881 agtcgagagt cgcgcggttc ttggacgctc tatcggtaaa gaagcccgtg tcgttgtcgc 1733941 cgtcactgac caaggttttg cgaataagct gatcagcttg ctcgattaat atttttgggg 1734001 gtgaacgaat ggctaaaatg agagtatacg aatatgcaaa agcgttaaat gtttcaagta 1734061 aggaaatttt gaccgcactg aagaacatgg atttagaagt gaataatcac atggccatgc 1734121 ttgaagaaaa ggccattaaa aagctagatg ccaaatataa aaaaggcggc gcagctgcta 1734181 aatctcaaaa gccagcagaa acgaacaaaa acaaacagcc acaaggggtt aatcagcaat 1734241 cagctggaaa tcaaccaaat aaaattcgag acggaaagaa gaatgacgtg cagaataatc 1734301 aatttaacaa aaacaagaag aataacaaca acaaaaaaaa taaacgcaac aacaacaata 1734361 ataaaaacca acatcagcaa aagcctgtaa agccgaaaaa agagcttcct gagaaaatta 1734421 cattctctgg cactttaaca gttggcgcac ttgctgaaga gcttggcaaa gagccttcag 1734481 aactcattaa aaagctgatg cttcttggcg taatggcaac cattaaccaa gagcttgata 1734541 aagacacaat cgaactcatt gcatcagaat atggtgttga aacagaagag gtcattgtgc 1734601 ttgaagaaac agagctggaa aaatacgaag agcctgataa tgaagaggat cttgaaattc 1734661 gtcctcctgt cgtgacaatc atgggccacg ttgaccatgg gaaaacaacg cttcttgaca 1734721 gcatccgtaa aacaaaggtt gttgaagggg aagcaggcgg aatcactcag catatcggcg 1734781 cttatcaaat tgaagagaac ggcaagaaaa tcacgttctt ggatacaccg ggccacgccg 1734841 catttacaac aatgcgcgca cgcggtgcag aagtaactga tattacgatt cttgtcgtag 1734901 ctgccgatga cggtgtcatg ccgcaaacag ttgaagcgat taaccatgca aaagcagcag 1734961 aggttccaat catcgttgct gtgaataaaa tagataaaga atccgcaaac cctgaccgtg 1735021 taatgcaaga actgacggaa tacggacttg tccctgaagc ttggggcgga gaaaccattt 1735081 ttgtgccgct ttccgcttta actggaaaag gcattgatga gctcgttgaa atgattttgc 1735141 ttgtcagtga ggtagaggaa ctgaaagcga atccgaatcg tcaggcaaaa ggaacggtta 1735201 ttgaagctga actcgataaa ggcagagggt cagtcgcgac gttgctcgta cagactggaa 1735261 cactgcatgt cggtgatccg atcgtagtcg gcaatacatt tggccgtgtc cgtgcaatgg 1735321 tcaacgacat tggccgccgt gtgaaaactg ccggcccgtc aactccggtt gaaattaccg 1735381 gtttgaatga tgtccctcaa gcgggagacc aattccttgt ctttaaggat gaaaaaacag 1735441 ctcgttctgt cggtgaagcc cgtgcttcga aacagcttga agagcagcgc agcgataaag 1735501 cgaagctcag tcttgatgat ttatttgagc aaattaagca aggtgatgta aaagacatca 1735561 acctcatcgt aaaagctgac gttcaaggat ctgctgaagc tttaacggct gcacttcaaa 1735621 aaattgaagt agaaggcgtt aaagtgaaaa tcatccatac aggcgttggt gcgattactg 1735681 aatcagacat tatcttggca tctgcttcca atgcaattgt tatcgggttt aatgtgagac 1735741 cggacggaaa tgctaagagt acggctgaag ctgaaaatgt agatattcga cttcaccgta 1735801 tcatttacaa agtaatcgac gagattgaag ctgccatgaa aggtatgctt gatcctgaat 1735861 atgaagaaaa agtaattggt caagtagaag tacgccaaac attcaaagta tctaaaatcg 1735921 gtacaattgc cggcggatat gttactgaag gaaccattac gcgcgacagc ggcctccgtt 1735981 taattcgtga cggcgtcgtc atctttgaag gcgaagtaga tgttctgaaa cgctttaaag 1736041 acgatgtgaa agaagtttca caaggctatg aatgtggtat tacaattaag aaatacaatg 1736101 acattcgtga aggtgacatc cttgaagcgt ttgtcatgca agaaattgaa agaacgtgat 1736161 cggatttgcg gagtgtgaat gcatcattta tgatgcagga tcgctaaaag aaaagcgtgc 1736221 cgttctgaag cggattttaa ccagggttca aaacaagttc aatgtttcga tttcggagat 1736281 tggctatcag gacacctggc aaagaaccag cttcggaatc gccgctgttt cttcctctcg 1736341 cgttcaaaca gaaaaagaac tgcagcgcgt cctagcgttt atcgattctt ttcctgaaat 1736401 tgaacggacg atcactagga cagagtggtt ttaacttaga ggtgattgaa ttgagtatga 1736461 gagcaaaccg tgtcggcgag caaatgaaaa aagaactcgg tgatattatc agccgcaagc 1736521 tgaaagaccc gagaattggt tttctgacag taacggatgt acgtgtatca ggtgatttgc 1736581 aaattgcaaa ggtgtatatc tcggttctcg gtgacgagaa aaaacgggaa gaagcgctga 1736641 aagggctggc aaaagcgaaa ggatttatcc gatccgaaat cggcagccgc atcagacttc 1736701 gaaaaacgcc tgaaattgaa tttgagttcg atgaatcaat cgattacggg aatcggatcg 1736761 aaacactgat tcacgaatta cattcagaga aaccatctga ataaaaaaag agaggatagg 1736821 cgtatatcgt ctgtcctctt tcttcgttta taagaaaaaa actcaaaaga aggagtgaaa 1736881 ggcaaatggt taacggagtt ctccttttac ataaacctgt tggcatgaca tcgcacgact 1736941 gtgtcatgaa gatccgaaag ctgttaaaaa caaaaaaagt aggacataca ggaacgctcg 1737001 atccggaagt atcaggcgtg cttccgattt gtgtaggaag agcgacaaaa atagtcgaat 1737061 acttaactga aaaatctaaa acgtatgatg cagaaataac attgggcttt tcaaccacaa 1737121 cagaggatca aaccggagaa acggtggaaa caaagcctgt caatcacgac attgataaag 1737181 cggatgtaga aaaggtttta aacagtttaa aggggaaaca agaacaaatt ccgcccatgt 1737241 attccgctgt aaaagtaaac ggcaaaaaat tatacgaata cgcaagagca gggattgaag 1737301 tagaacgtcc gaaacgtatg ataaccattg aagacattgc cctgacaaca gagattaaac 1737361 atcatggaga aaccgcaagc ttccggttta cagtgacttg ctccaaaggg acctatgtaa 1737421 ggacgctggc ggtcatgatc ggagaaaagc tcggatatcc ggcccatatg tctcatttaa 1737481 tccgtacggc atccggagat ttttctctcg acgaatgctt tacttttgat gaactcgaag 1737541 cacaggccca atccggaacc gtggaagagc atacagttcc tattgaacgt gcgctcaatc 1737601 atttgccgaa atggatcata agtgatacat tagctaagaa agtagaaaat ggggctttgc 1737661 ttgagacgcc cgagcagttt tctgaaatga caagtggaga ccgtattgcc gtctttactg 1737721 aatccggaac ctgcttggcg atctatttcc ctcatcctgc aaaaaaaggg ctgttaaagc 1737781 cggcaaaagt attgatgcaa aaaagcgaac aatagaaaaa aggtgaccgt tctgtgaaga 1737841 cgatacatat tacacatcct catcatttaa taaaagagga gcaggcaaaa tcagtgatgg 1737901 cgttaggtta ttttgacggc gttcatctcg ggcatcaaaa ggtaatcggc acagcgaagc 1737961 aaatagccga agaaaaaggt ctgacattag ctgtgatgac ctttcatccc catccttctc 1738021 acgtgttggg cagagataag gaaccaaagg atctgattac gcctcttgaa gacaaaataa 1738081 accaaattga acaattaggc acagaagttc tgtatgtcgt taaatttaat gaagtgtttg 1738141 cttctctttc tcctaagcag tttatagacc agtatattat cggccttaat gtgcagcacg 1738201 cagtggcagg ctttgacttt acgtacggca aatacggcaa gggaacaatg aagaccatgc 1738261 cggatgattt agacggaaaa gctgggtgca caatggtaga aaaattaacg gagcaggata 1738321 aaaaaatcag ttcttcgtat atccgtaccg cgcttcaaaa cggagatgtt gaattggcga 1738381 atgtcttgct tggacaacct tattttatta aaggaattgt cattcatggt gataaaagag 1738441 ggcggaccat cgggtttccg acagcgaatg tcggtttaaa taacagctat atcgttccgc 1738501 ccacaggtgt atatgccgta aaagcggaag tgaacggcga agtttacaat ggcgtttgca 1738561 atattggcta taagccaacg ttttatgaaa agcgccctga acagccttcc atcgaggtca 1738621 atctgtttga tttcaatcaa gaggtatatg gagccgctat aaaaatcgaa tggtacaaac 1738681 ggattcggag cgagcggaaa ttcaatggca tcaaagaatt aactgagcaa attgagaaag 1738741 ataagcagga agccatccgt tatttcagca atttgcggaa ataacttgca acgcacgcaa 1738801 attttattct aaaatatttg catataggca cgatttttag tatgatagtt ttcgtagtct 1738861 taaaaccatt gcttggcaat ccgaagtcac cgacggttgc taggtaactg gggctaaata 1738921 tgatttggag gtgaaacagg atggcaatta ctcaagagcg taaaaaccaa ctcatcaatg 1738981 agttcaaaac acacgaatct gatactggat ctccagaagt tcagatcgct atcctaactg 1739041 actcaattaa caacttgaac gagcatttac gtactcacaa gaaagaccac cactcacgtc 1739101 gcggtcttct taaaatggta ggtaagcgtc gtaatcttct tacgtatctg cgtaataaag 1739161 acgtaactcg ttaccgtgag ttaattaaca aactaggctt acgtcgataa tcgtaaaaag 1739221 cgggaggatt cccgcttttt tatcgtatta aagcgaaatt tcttataaca aatcattgaa 1739281 atccttttac atactacttt gacattgata tgttcaattc atttcgttca taataggagt 1739341 aattgattat ttcacacaac gaagagagga gttcgtaatt gtatgggaca agaaaaacat 1739401 gtctttacca tagattgggc cggaagaacg cttaccgttg aaaccggcca gcttgccaaa 1739461 caggcaaatg gtgctgtgat gatccgctac ggtgatacag cagtacttag tacagcaacc 1739521 gcttcaaaag aacctaaacc gcttgatttc ttccctctta ctgtaaacta tgaagaaaga 1739581 ttatatgcgg tagggaaaat tccgggcgga tttattaaaa gagaaggacg tccaagtgaa 1739641 aaagcggttc ttgccagccg tttaattgac cgtccgatcc gtcctttgtt tgccgatgga 1739701 ttccgtaatg aagttcaagt catcagcatt gtcatgagtg ttgaccaaaa ctgctcttca 1739761 gaaatggctg ccatgttcgg ttcatctctt gcactttctg tatcggatat tccgtttgaa 1739821 ggaccgattg caggggttac tgtcggacgc attgatgatc aatttatcat taacccgaca 1739881 gtcgatcagc ttgaaaaaag cgatatcaat cttgtcgttg ccggcacgaa agatgcgatt 1739941 aacatggtag aagcgggagc ggacgaagtt cctgaggaaa tcatgcttga ggccattatg 1740001 ttcggccatg aagagattaa acgcctgatt gcattccaag aagaaattgt tgcagcagtc 1740061 ggcaaagaga aatctgaaat taagctcttt gaaattgatg aagagcttaa tgaaaaagta 1740121 aaagctttgg cagaagagga tctgctgaaa gccatccaag ttcatgaaaa gcatgcccgt 1740181 gaagatgcca ttaacgaagt gaagaacgca gttgtggcaa aattcgagga tgaagaacat 1740241 gatgaagaca caatcaagca agtgaagcag attttatcca agcttgtgaa aaatgaagtt 1740301 cgccgcctga ttactgaaga gaaagtaaga ccggacggcc gcggtgtcga tcaaatccgt 1740361 ccgctctctt cagaggttgg cctcttgcca agaacgcacg gttcaggtct atttacaagg 1740421 ggacaaactc aggccctcag cgtatgtacg ctaggtgctc tgggagatgt gcaaatcctt 1740481 gacggcttag gtgtcgaaga gtcgaaacgg tttatgcatc attacaactt cccgcaattc 1740541 agcgttgggg aaacaggacc gatgcgcgga ccgggacgtc gtgaaatcgg acacggagca 1740601 ctgggtgagc gtgcgcttga gccagttatt ccgtctgaaa aagacttccc ttatactgtc 1740661 cgtcttgttt cagaagtgct tgaatcaaac ggttctacat ctcaagcaag catttgcgca 1740721 agcacacttg caatgatgga tgccggtgta ccgattaaag cgccagttgc tggtattgcg 1740781 atgggtcttg tcaaatcagg cgaacattac actgtcttga ctgacatcca aggcatggaa 1740841 gacgcgctcg gagatatgga ctttaaagta gcgggaactg aaaaaggcgt aacggccctg 1740901 caaatggaca ttaaaattga aggcctttcc agagagattc ttgaagaagc gcttcagcag 1740961 gcgaaaaagg gcagaatgga aatcctcaac agcatgcttg caacattaag cgaatcaaga 1741021 aaagagcttt ctcgatatgc gcctaagatc ttaacaatga ccattaatcc tgataaaatc 1741081 cgcgatgtca tcggaccaag cgggaaacaa atcaataaga tcatcgaaga aaccggtgtt 1741141 aaaattgata ttgagcagga cggcacaatc tttatttcct ctacagatga aagcggcaac 1741201 caaaaagcga aaaaaatcat cgaagacctt gtgagagagg ttgaagtcgg ccaactttac 1741261 ctaggtaaag tgaaacggat tgaaaaattc ggggctttcg ttgaaatttt cagcggaaaa 1741321 gacggtttgg tgcacatttc agagcttgcg cttgaacgcg tagggaaagt tgaagatgtt 1741381 gtgaaaatcg gagacgagat tcttgtcaaa gtcactgaaa ttgataaaca aggacgagtg 1741441 aatttatccc gcaaagcggt gctccgtgaa gagaaagaaa aagaagaaca acaatcttaa 1741501 atgaaaacat aaaaggagcc tgggagaccc ggcttcttta ttttgaagct tttcaaaagc 1741561 aggcgggttc taccttgtcc ttctccttca taatgtgagg tgaggggggg acagaacatg 1741621 tacaaaaaat ttgtaccgtt tgccgttttt ttatttcttt tttttgtctc atttgagatg 1741681 atggaaaatc cgcatgcact tgattatata ggggcaatga aaaaagatac ggtgactgtc 1741741 acggcgtcaa aagacccgtt atatgaagaa ttgcttcaaa aagcgccgga gtacgaagtt 1741801 aagccccaga atgcaagaat tgataaagtg tggaaaagca ttccaggcta caatggatta 1741861 aaggtcaata ttgaacaatc atataaaaaa atgaaacagc atggtaagtt tcgggaaaaa 1741921 gatttggtgt acagtcaagt aaaaccaagt gttcatcttg agtcacttca gcctgagcct 1741981 atttataaag gaaatcctga caaaccgatg gtggcttttt taatcaatgt ggcatgggga 1742041 aatgagtatt tggaaaaaat gcttcctatt ctgcaaaagc accaggttaa agctacgttc 1742101 tttttagaag gcaattgggt gagaaacaat gtacagctcg ctaagaagat tgcaaaagac 1742161 ggacatgaaa tcggaaatca ttcatacaat catccggata tgagcaaact gactacagga 1742221 agaatttccg agcagctcga caagactaat gaacaaatag aacaaacgat cggcgttaag 1742281 ccaaagtggt tcgctccgcc aagcggaagt ttcagaaaag cggttatcga cattgcagca 1742341 gagaaacaga tgggaacagt catgtggaca gttgatacaa tcgattggca aaagccggct 1742401 ccgtctgtac ttcagacgag agtgttaagc aagatacata atggtgccat gattttaatg 1742461 catccgactg accctacggc ggaaagtctt gaagcgctga ttacacagat aaaagacaaa 1742521 ggatatgcgc ttggaacagt cactgaacta atggatgaaa caagactatt gaagtaacag 1742581 atgaaggcag cttgtctttg aataggagga acaaatttga ttaaacgata tacgtgtcaa 1742641 aatggtgtaa gaattgtgct ggaaaataac ccgacagtcc gttctgttgc gatcggcgta 1742701 tggatcggca caggttcgag acatgaaacg ccggagataa acggaatttc tcacttttta 1742761 gagcacatgt tctttaaagg gacgagcaca aaatctgcac gcgagatagc agaatctttt 1742821 gatcgtattg gcggccaggt caatgcgttt acttcaaagg aatatacctg ctactatgca 1742881 aaggtgcttg acgagcatgc gaattacgcg ctggacgtat tagcagatat gttctttcat 1742941 tcaacgtttg atgaaaacga gctgaaaaaa gagaaaaatg tagtatatga agaaattaaa 1743001 atgtatgaag atgcgccgga cgacattgta catgatttat tgagcaaagc cacttacggc 1743061 aatcattctt taggctaccc aattttagga acggaagaaa cgcttgcttc ctttaacggt 1743121 gactctctca gacaatacat gcatgattat tatacgccgg accgagtggt gatttcggta 1743181 gcgggcaata tatctgacag ttttatcaaa gatgtagaaa aatggttcgg gtcatacgag 1743241 gcgaaaggca aagcgacagg ccttgagaag cctgagttcc acacggaaaa actgacgaga 1743301 aaaaaagaaa cagagcaggc tcatttgtgc cttggattta aaggcttaga ggttggccat 1743361 gaacgtattt atgatttaat cgtcctcaac aatgtgctcg gaggcagcat gagcagccgg 1743421 ctgttccaag atgtgcgtga agataaagga cttgcttatt ctgtttacag ctatcacagc 1743481 tcatatgagg acagcggaat gctaacgatt tacggcggaa cgggtgcaaa tcagcttcag 1743541 cagctgtcgg aaacaattca agaaaccctg gccacattaa aacgtgacgg cattacctcg 1743601 aaagaactgg aaaacagcaa agagcaaatg aagggaagct taatgctgag cttagaaagc 1743661 acaaacagca aaatgagccg aaacggaaaa aatgaactgc tgctcggcaa acataaaaca 1743721 ttagatgaaa ttatcaatga attaaacgcc gtgaacttag agcgtgttaa tggccttgcc 1743781 agacaattgt ttaccgaaga ctatgcatta gcacttatca gcccttccgg caatatgccg 1743841 tcttaaaaag gaaagcctgc cccataatgg agcaggcatt ttttaatccc tttcatcata 1743901 catagtacaa gggggtgaca gacatgcggc tcagtgaatt atcgggaaag gaaattgtag 1743961 acatcaaaag agctgaacgg ctcggagtgc tcggccagac cgatttggaa atcaatgaac 1744021 aggatggaca gattacagca ctcctcattc ccacagttaa gtggtttggt ttgagaaagc 1744081 aaggtcatga cattcgtgtc ccatggcacc atattcaaaa gatcggttca gatatgatta 1744141 tattagatgt acctgaggaa atgcctcctc gacaagagta aatagcccaa ttgactgtga 1744201 agcgggctct aaagaaaaca tctgaaacat cggctgccgg agccgatgtt tttttatatg 1744261 gaaaaagcgc atcttttata ttcaccggta tttccttttg atcataagat gaaggggagc 1744321 ttaacaacta gagatccagt atatacaaag aaggtgaacg tttagaatgt taaccggatt 1744381 gaaaattgca gttatcggcg gtgacgcaag acagctcgaa attataagaa agctcactga 1744441 acagcaggct gacatctatc ttgtcggttt tgaccaattg gatcacggtt ttaccggggc 1744501 agtaaaatgc aatattgatg aaattccttt tcagcaaata gacagcatca ttcttccagt 1744561 atccgcgaca acaggagaag gtgtcgtatc gactgtattt tcgaatgaag aagttgtgtt 1744621 aaaacaggac catcttgaca gaacgcctgc acattgtgtc attttctcag gaatttctaa 1744681 cgcctattta gaaaacattg cagctcaggc aaaaagaaaa cttgttaagc tgtttgagcg 1744741 ggatgacatt gcgatataca actctattcc gacagtagaa ggaacgatca tgctggctat 1744801 tcagcacacg gattatacga tacacggatc acaggtggcc gttctcggtc tggggcgcac 1744861 cgggatgacg attgcccgta catttgccgc gctcggggcg aatgtaaaag tgggggcaag 1744921 aagttcagcg catctggcac gtatcactga aatggggctc gttccttttc ataccgatga 1744981 gctgaaagag catgtaaaag atatagatat ttgcattaat accataccga gtatgatttt 1745041 aaatcaaacg gtactttcta gcatgacacc aaaaacctta atattggatc tggcctcacg 1745101 tcccggggga acggatttta aatatgccga gaaacaaggg attaaagcac ttcttgctcc 1745161 cgggcttcca gggattgtcg ctcctaaaac agctgggcaa atccttgcaa acgtcttgag 1745221 caagcttttg gctgaaatac aagctgagga ggggaaataa ggatgtcgtc attaaaagga 1745281 aaaagaatcg ggtttgggct gaccgggtcg cattgcacat atgaagcggt tttcccgcaa 1745341 attgaggagt tggtcaacga aggagctgaa gtccgtccgg ttgtcacatt taatgtaaaa 1745401 tctacaaata cccgatttgg agagggcgca gaatgggtta aaaaaattga agacctgact 1745461 ggatatgagg ccattgattc gattgtaaag gcagaacctc ttgggccgaa gctgcccctt 1745521 gactgcatgg tcattgcgcc tttaacaggc aattcaatga gcaagctggc aaatgccatg 1745581 acggacagcc cggtgctgat ggcggcaaaa gcgacaatcc ggaacaatcg gcctgtcgtt 1745641 ctgggtatct cgacaaatga tgctcttggt ttaaacggaa caaatttaat gaggctcatg 1745701 tcaacaaaaa atatcttttt tattccattc gggcaagatg atccatttaa aaaaccgaat 1745761 tcaatggtag ccaaaatgga tctgcttccg caaacgattg aaaaggcact catgcaccag 1745821 cagcttcagc cgattctagt tgagaattat cagggaaatg actaaattta cagaaaatct 1745881 ttcccaaact aaaaaattcg gtcatcaccc gcatattcta tggtaaaata aaacgtaaaa 1745941 tcatagtcaa atcaattcaa tgaagctgat tggcggaagg agttttacag atgggaagag 1746001 gtttacacgt agctgttgtc ggagcgacag gggctgtggg acaacaaatg cttaaaacac 1746061 ttgaagacag aaactttgaa atggacacac ttacattgct atcttcaaaa cgctctgcgg 1746121 ggacaaaagt cacgtttaaa ggccaagagc tgactgttca ggaagcttct cctgagagct 1746181 ttgaaggggt aaatattgct ttgttcagcg ccggcggaag cgtatcacaa gcattggcac 1746241 cagaagctgt aaaacgcggc gctattgtta tagataatac gagtgcgttc cgcatggatg 1746301 aaaatacacc gcttgttgtg ccagaagtga atgaggcaga cttgcatgaa cacaacggca 1746361 ttattgccaa tccaaactgc tctacaatcc aaatggttgc ggcacttgaa ccgatccgca 1746421 aagcatatgg cttaaacaag gtcatcgtat caacttacca ggcagtatca ggagcgggta 1746481 atgaagctgt aaaagagctt tacagccaaa cacaggcgat tttaaataaa gaagaaatag 1746541 agcctgagat catgcctgta aaaggtgaca aaaaacacta tcaaatcgcc ttcaacgcga 1746601 ttccgcaaat cgataaattc caagataacg gctatacgtt tgaggaaatg aaaatgataa 1746661 atgaaacgaa aaaaatcatg cacatgcctg accttcaagt agcggctaca tgtgtgagac 1746721 tgccaatcca aactgggcac tcagagtccg tctacatcga aatagaccgt gatgacgcta 1746781 cagttgaaga tattaaaaat ctattgaaag aagctccggg cgtgacactt caggatgatc 1746841 caagccagca gctttatccg atgcctgctg atgctgtcgg caaaaacgat gtgtttgtag 1746901 gccgcatccg caaagacttg gacagagcaa acggttttca tttatgggtt gtttctgata 1746961 acctattaaa aggcgcggca tggaactctg ttcaaattgc agaaagcctg aaaaaactaa 1747021 acctcgtata aaagagagaa ttttctaaag acgaatagaa gagagtaagg cgctatcagc 1747081 ctgctctctt ctgttacgtc cgaataattt ggagtgaaaa cagtgaagat aattgttcaa 1747141 aagttcggcg gaacatcagt aaaagatgat aaaggccgca aactggcttt agggcatatt 1747201 aaagaagcaa tcagtgaagg atataaggtt gtcgttgtcg tttcagcgat gggccgaaaa 1747261 ggggacccgt atgcaacaga ttctttgctc gggctgcttt acggcgatca gtcagcgatt 1747321 tctcctaggg agcaggattt gcttttatct tgcggagaga ctatttcctc tgtcgtcttt 1747381 acaagcatgc tgcttgataa cggtgtgaaa gcagctgcgc tgacaggggc tcaggctggc 1747441 tttttaacga atgatcagca tactaatgcg aaaatcattg aaatgaaacc ggagcgttta 1747501 ttcagtgtgc tcgccaatca tgatgcggta gtcgtcgcag gcttccaggg cgcaactgaa 1747561 aagggtgata caacaacaat cggcagaggg ggcagcgata cgtctgcagc cgcactcgga 1747621 gcagctgttg atgcggaata catcgatatt ttcaccgatg tagaaggcgt gatgactgct 1747681 gacccaagag tggtagaaaa tgcaaaaccg cttcctgttg tgacgtatac ggaaatctgc 1747741 aacctggcgt atcagggggc caaggtcatt tctccgcgtg ctgtggaaat cgcaatgcag 1747801 gccaaggttc cgatccgcgt ccgttcgact tattcgaatg ataaaggcac attggtgaca 1747861 tcacatcact cttccaaggt cggcagtgat gtttttgaaa ggctgattac gggaatcgcc 1747921 catgtcaaag atgtcacgca gttcaaagtg cctgcgaaaa tcggccagta taacgttcag 1747981 actgaagtgt tcaaggctat ggcaaacgct ggaatcagtg tcgatttctt taacattaca 1748041 cctagtgaaa tcgtctatac ggtagccgga aataaaacag aaacagctca gcgtatttta 1748101 atggatatgg gctatgatcc aatggtgacg agaaactgcg cgaaggtatc ggcggtcggc 1748161 gcgggcatta tgggtgttcc cggtgttacg tccaaaattg tatcggctct ttcagaaaaa 1748221 gaaattccga tccttcagtc ggctgacagc catacgacga tatgggtgct cgtccatgaa 1748281 gcggatatgg ttcctgctgt aaacgctttg catgaagtgt ttgaactttc gaagtaaatg 1748341 tgattgaatc atgatgaggt gaataaaatg aatttcggaa atgtgtctac agcgatgatt 1748401 acaccctttg acaataaagg gaacgtagac tttcaaaaac tgtctacact gattgattac 1748461 ttgttgaaaa acggaacgga ttctttagta gtagcgggaa caactggaga atctccgacc 1748521 ctttcaactg aagaaaaaat tgcgcttttt gaatatacgg taaaagaagt aaacggacgg 1748581 gtgcccgtta tcgctggtac tgggagcaac aacacgaaag attccattaa gctgacaaaa 1748641 aaagctgagg aagcgggcgt ggacgctgtt atgcttgtta ccccgtatta caataaacct 1748701 tctcaagaag gaatgtacca gcattttaaa gcaattgcgg cagagacatc tcttccggtt 1748761 atgctctata atgttcctgg ccgtacggtt gcttctcttg ctcctgaaac gacgatccgt 1748821 ttggcggcag acattccgaa tgtggttgcg attaaagaag cgagcggaga cctcgaagcg 1748881 attacaaaaa ttattgctga aacacctgaa gacttctatg tctattcagg ggatgatgct 1748941 ctaacgcttc caattctttc agttggaggt agaggagttg tgtcagtggc gagccatatt 1749001 gcaggcactg atatgcagca aatgatcaaa aattatacga atgggcaaac agctaatgcg 1749061 gcactgattc atcagaaact gctgccgatt atgaaggaac tgtttaaagc gcctaatcct 1749121 gctccagtca aaacagcgct tcagctgaga ggtcttgatg tcggttctgt gcgtctgcct 1749181 ctagtcccat taactgagga tgaacgtctg agcttaagca gcacgatcag cgaactgtaa 1749241 gaaaatttca tacagtgaaa caaacgcggt cattctcaca ttcagctgag tttgaccgtt 1749301 tcttttacat attggttttc cctaaacctt ctgctttatc ttgttttcta aatttacttt 1749361 cagttataat aggaacaagt gatgatggac gggtatgaga ctaggaggat atagattttg 1749421 aaaaagaaaa atacagaaaa cgttagaatt atcgcccttg gcggtgtcgg agagattggg 1749481 aagaaccttt atgtcattga aattgactca gacatatttg tcgttgatgc cggccttatg 1749541 catccagaaa acgaaatgct cggtattgat gtagtgattc ctgacatatc atatttgatt 1749601 gaacgggctg accgcgtcaa ggcaatcttt ttaacgcacg ggcacgatga aaatatcggc 1749661 ggcgtttttt acttattaaa caagctgtcc gttccagtgt acggaacaaa actgacgctt 1749721 gcactgttaa gagagaaatt aaaacaatac ggacataacc gaaaaactga tttaagagaa 1749781 attcactcca aatctgtcat tacatttgaa tcaacaaagg tatcgttctt tagaacgatt 1749841 cacagcattc ctgattctgt aggtgtgagc tttaaaacat cacttggatc tattgtatgc 1749901 acgggagact tcaaatttga ccaaacacct gcacttaatc agacgtgcga cattggcgag 1749961 atcgccaaga tcggcaatag cggcgtgctc gctctgcttt ctgacagtgc aaatgcggaa 1750021 cggccgggtt acaccccttc ggaagcggct gtcagcggag aaatttcgga tgcgctgtat 1750081 aattcacaga accgggtgat tattgctgtt ttcgcatcca atattaaccg gattcagcaa 1750141 gtcattcatg cagcggctca aaatggcaga aagattgccg tagccggaaa aaatcttcaa 1750201 tctgtcctgc agctggcgag aaagttagga tatattgaag cagatgatga attgtttatt 1750261 tctgtacagg atgtcaaaaa atatccgaag cgcgaagtgg ccattattac agccggaagc 1750321 caaggtgaac cattagctgc tttgacaaga atggcaaaca aagctcacaa acagctgaac 1750381 attgaagaag gggatacggt ggtcattgcg tcaactccga ttcccgggca ggaactcatt 1750441 tactctaaaa cagtagatct tcttgcgaga gccggtgcac aagtcatctt tgcccaaaag 1750501 cgtgttcatg tatcaggcca cggctcacaa gaagagttaa agctgatgat caacctgctt 1750561 aaaccaaaat atttgattcc tgtaaacggc gaatacagaa tgcaaaaagc tcattcaaaa 1750621 atcgctgaag aaaccggcat gaagcgcagt gacatcttct taattgaaaa aggcgacgtc 1750681 gttgaattcc gcggccaaaa cgtaaaaatt ggggataaag ttccttacgg caatatttta 1750741 attgatggtt taggtgtcgg tgatatcggc aatatcgtat tgagagaccg ccgcttgctt 1750801 tcacaggacg gaattttaat cgttgtcatt acacttgata aacaaaagaa acatcttgta 1750861 tcaggaccag aaattatcac tcgcggcttt gtttatgtaa gagagtctga aggtcttatc 1750921 gtacaggcta ctgagcttgt acggtccatc gtgacagaag cgactgaaac atcaaatgtc 1750981 gaatggtcaa cgctgaagca ggcaatgcgg gatgctttga accaattcct ttatgaaaaa 1751041 acgaaacgta aaccgatgat catcccaatt attatggaag tataatgact gactaaagac 1751101 cggagctgct ccggtcttta ttttttgtcc ttcaagccgg gattgaatga agtatctttg 1751161 ttcataatac aaagagaaac tcggaaagga tgaaagcgag atggatcatc gtatggaaaa 1751221 cacagaagaa gagcgtcctg aaaaaaatga tgcgaaggac agcattatga ataaaataca 1751281 gcagcttggt gaaacgacgc ttccgcagct gccccaagat acaaatattc attgtctgac 1751341 cattatcgga caaattgaag gccatgttca gcttcctccg caaaacaaaa caacaaaata 1751401 tgaacatgtc atcccgcaga ttgtggcaat tgaacaaaat cccaaaattg aaggcttgct 1751461 gatcatatta aatactgtcg gaggagatgt tgaagctggt cttgccatag cggaaatgct 1751521 tgcatcttta tcgaaaccga ccgtttctat cgtgcttggc ggggggcatt caatcggcgt 1751581 tccgattgct gtatcctgtg attacagcta tatcgccgaa acagcaacga tgacgattca 1751641 tccagttagg ctcaccgggc tggtcatcgg ggtgccgcaa acgtttgaat acctggataa 1751701 gatgcaagaa agagttgtta aatttgtgac aagccattcc aatataaccg aagagaagtt 1751761 taaagagcta atgttttcaa aaggaaactt aacacgcgat atcggaacaa atgtagtcgg 1751821 taaggatgca gttaaatacg gattgatcga tcacgcaggc ggtgtcggac aggcaatcaa 1751881 taaactgaat gagctcatcg atgaagcaag gaaagaagaa ggacggatga ttcaatgatt 1751941 ctttataccg tgatgcctca ggaaattgtg tttgcagaac agaaccaaga gacaagcgca 1752001 catgagcaaa ttgaatataa aggtgtaccg cttctagtcg aaatgaaagg gaatgaagcg 1752061 gaagtcattc aaatcatgag caccaatcca atgcattttc tgcatccgga catttcaccg 1752121 ggacaaaagc tgaaattaaa cgtataagaa tccaaccctt ttttaagggc aaaatatgct 1752181 ataatagggg aatcctacag aaaaaacgca gcctgtaaac ggctgctttc ttcattatgt 1752241 atgaacttac attttttaac gcagtaaggt gatgagtgtg gcaaagaaaa aacgaaaatc 1752301 aagaaaaaaa caggcgaaac agctcaatat aaaatacgag ctcaacggat tgctgtgtat 1752361 agccatttca attatcgcaa tcttgcagct gggggtagtc gggcaaacgt ttatctattt 1752421 gttccgcttt tttgctggag agtggtttat tttatgcttg ttaggtttat tggtgttagg 1752481 agtctcactg ttttggaaga aaaaaacccc aagcctttta acgagacgaa aggccgggtt 1752541 gtactgtatt atcgcaagca tattgctgct ttctcacgtg cagctattta aaaatttgac 1752601 gcacaaaggg tctattgagt ctgcaagcgt ggtgcgcaat acgtgggaat tgtttttaat 1752661 ggacatgaat ggcagctctg cttcacctga tttaggcgga gggatgatcg gtgcgctgct 1752721 gtttgcggct tcacactttt tgtttgcgtc gactggttct cagatcatgg caattgtcat 1752781 gattttgatc ggaatgattt tagtaacagg acgctcgctg caagaaacgc taaaaaagtg 1752841 gatgagcccg attggacgtt ttataaaaga acaatggtta gcatttattg atgacatgaa 1752901 atccttcaaa tcaaatatgc agtcatcgaa aaaaacgaaa gcgccgagca aaaaacaaaa 1752961 accggcccgc aaaaaacagc aaatggaacc ggagcctcct gatgaagagg gggattatga 1753021 aacagtatcg cctcttattc attcagagcc gattatctca agcttttctg atcgtaatga 1753081 agaggaagag tctccagtta tagaaaagcg cgccgaacct gtgtcgaagc cgcttcagga 1753141 catccaaccg gagacaggtg atcaggaaac tgtttctgct cctcctatga cctttacaga 1753201 gctcgaaaat aaggattacg agatgccgtc actggatttg ctggcagatc cgaagcatac 1753261 cggccagcag gctgataaaa agaatattta tgaaaatgcg agaaagcttg aacgcacatt 1753321 ccaaagcttt ggcgtaaagg cgaaagtcac acaggttcat ctcggaccgg ccgtaacaaa 1753381 atatgaagta tatcctgatg tcggagtgaa ggttagcaaa attgtcaatt taagcgatga 1753441 tttagcgctt gcgcttgctg cgaaggatat caggatcgaa gcgcctatac caggcaaatc 1753501 agcaatcgga attgaagttc caaacgcaga agtggcaatg gtttcgctga aagaagtgct 1753561 ggagtctaaa ttgaatgaca gaccggatgc gaagctgtta attggactcg gccgcaatat 1753621 ttcaggtgaa gctgtattgg ctgagttaaa caagatgccc caccttttgg tcgcaggcgc 1753681 aaccggtagc gggaaaagtg tctgtgtcaa cggcattatt acaagtattt taatgcgggc 1753741 gaaaccgcat gaagtgaaaa tgatgatgat cgatcctaaa atggtagagc taaatgtcta 1753801 caacgggatt ccgcatttgc ttgctcctgt tgtaaccgat ccgaaaaaag cgtcgcaggc 1753861 tttgaaaaag gttgtcaatg aaatggagcg gcggtacgaa ttattttctc atacgggtac 1753921 aagaaatatt gaaggataca atgattatat aaaacgcgcc aacaatgaag aaggagcgaa 1753981 acagccagag ctgccttata ttgttgtcat tgtggacgag ctagccgatc tcatgatggt 1754041 cgcttcatct gatgtggaag attcgattac gagattgtcc caaatggcgc gggctgccgg 1754101 catccatctt attattgcga cacagcggcc atcggtggat gttatcacag gggtgatcaa 1754161 agcgaacatt ccgtcacgaa tcgcgttcag cgtatcttca cagacggatt caaggaccat 1754221 tcttgacatg ggtggcgctg agaagcttct tggccgcggc gatatgctgt ttttacctgt 1754281 aggggctaac aaacctgtcc gtgtgcaggg agcatttttg tcggatgacg aagtggagaa 1754341 ggtcgtcgac catgtgatta ctcagcagaa agcgcaatat caagaagaaa tgattcctga 1754401 ggagacgacg gaaactcatt ccgaggttac tgatgaactt tatgatgaag ctgttgaatt 1754461 aatcgtcggc atgcagacgg catctgtttc aatgctgcaa agaagattca gaattggcta 1754521 tacgagagcg gcgcgcctga ttgacgcaat ggaggaacgc ggtgttgtcg gaccgtatga 1754581 aggcagcaaa cctagggaag tattattatc aaaagagaaa tatgatgagc tctcttctta 1754641 atgaagggag ttccgctttc tatagttgtc aataatgata ttatgtaaac tgatcacctt 1754701 tctatttatt ttttcgacaa aacatgatat agttgtccca attgttcaat aatttttatc 1754761 gaaagtggtt tacggagggg aaacatgtct acaaaagctg ataatcggca cttgtatttg 1754821 aaagtaattg aacgaattaa agaggatata aaaaatggga tctacactga gaaggaaaag 1754881 ctgccttctg aatttgagct ttccaaaaag cttggtgtca gcagagcgac gctaagagaa 1754941 gccttgcgga tactggaaga agagcatgtg attatcagaa ggcatggtgt aggcactttt 1755001 gtccattcta agccgttatt tctttcgggt attgaacagc tgaacagtgt aaccaagatg 1755061 atagaacagg cgaatatgac ccctggcacg atttttctat catcacaagt gcttatgccg 1755121 tctgaagatg atacgaagag atttcacttg gcagaagggc aagaactttt ttaccttgaa 1755181 cgagtcagga cagctgacgg acagccgatt gtgtattgta tagacaaaat tccgatgaat 1755241 attttgccga attctttttc tcatcagcaa gaatctatgt ttgacctgct agagaaaaat 1755301 tcaggctccg taatcagcta tgcagtaact gatatagaac cgatcggcta tcacgatacc 1755361 atttctccag tgcttgaatg cgatccggaa acagctcttt tgctgttaaa acaaacccat 1755421 tacgatcagc acgataaacc ggtgctttat tctttaaatt attttagagc ggataaattc 1755481 agatttcatg ttttgcgtaa acgattctaa aaacggacgc ctgtatgtgt ctgttttttt 1755541 atttgcactg attcatgttt ctttgtacat actttcattc cggttaacgc aatatataag 1755601 ggatgacaag aaagtgaatg ggtgaaaatg ttgagagaga aaaatggaat gaaaaatatt 1755661 attgcattgt cttctgtccc gcttgtgatg acactcggga actccatgct gattcctgtt 1755721 cttccgatga tggagaaaaa gctgtctgtg acttcatttc aagtatcttt aatcattact 1755781 gtatattcag tagtagcaat tatttgcatt ccgattgccg gatatttgtc ggatcgtttc 1755841 gggagaaaaa aaatattgct tccatgcctc ctcattgcag gattgggggg agccgtagct 1755901 gcttttgcct cgacctatat gaaaaatcct tatgctatga tcttggcggg gcgggttctt 1755961 caaggcattg gttctgcagg tgccgctccg attgtcatgc cgtttatcgg cgacctgttt 1756021 aaaggagacg atgaaaaggt cagcgcgggt cttggcgata ttgaaaccgc caacacgtca 1756081 gggaaggtac tgagtcccat acttggagcc ttactggctt cttggtattg gtttgtaccg 1756141 ttttggttta ttccgttttt ctgtttgatc agctttttgc tcgtattgtt tttggtggcc 1756201 aagcctgaag aagatgaaga tgcgcctgct gtttctgagt ttattaagag tgtgaagaaa 1756261 atttttaaac aggatggtcg ctggctttat acggtcttca ttatcgggtg tgtcattatg 1756321 tttttgttat ttggcgtatt attttattta tcagatacgc tggagaacaa gtatgctatt 1756381 gacggagtag ctaaaggcgg attactggca atcccacttt tgtttttgtc aaccagttct 1756441 tttatagctg gcaaaaagat cggtaaagat aaaggccgaa tgaaattttg cgttgttaca 1756501 ggaatgattc tgttaaccct ttcgtttatt gccttgtggt ggaaccacag tttttatttt 1756561 ttatttgtct ttttaagctt tggcgggatt gggattggaa tggctcttcc tgctttagat 1756621 gcattgataa ccgaagggat tgaaagtgaa caatgcggaa ccatttcctc cttttacaat 1756681 agcatgcgct ttataggagt agctctcggt ccacctgttt ttgctgcatt aatgtctaat 1756741 gcaaactgga ttattttcat actctcggcg ttttgcagca tcgtttcttt atttttagtg 1756801 ctctttactg tagatgctaa aaaaagtgaa gaagaaaaaa acttagggac ggtctagcca 1756861 gccgtctttt tttgcgcttt cttgcacagt ttacaactgt acctatacag catgcggagg 1756921 ttattgtttc cttataaatc ctacagttgc tataattaca tgaaagagtg tttctgcgga 1756981 tgctgaaaat tggtcataat acatactaat taagaaatga acgaaggagg ttccatatgt 1757041 catatgttaa tgaactcaaa tcaaagcacg gcggtttaac cgcacacatt gtaaaaacag 1757101 aaaaattcaa aaccgtctcg cttattttta agatgcttgc gccgctgaca aaggatcaag 1757161 tcaccaaaag agcgcttctc ccgcatgtgc ttcttcgcgg aacgaaaagc catccgaaaa 1757221 ccgcaggatt gcgttcatac ttggatgagc tgtacggcac gtcagtatcg gctgatctta 1757281 cgaaaaaagg agagcggcat gtcattacgt tcaggcttga aatcccgaat gaaaaatatt 1757341 taaaagacca aacgccgctt ctcgagaaag ggctccagct tctcgcagaa ctcgtctttt 1757401 cacctgcttt ggagggagac gcttttcagt cacaatatgt ggctcaagaa aaacggacgc 1757461 ttaagcaaag aatccaagcc gtctatgatg ataaaatgcg ttattcgaat ttaaggctga 1757521 tacaggaaat gtgcaaaaat gatccttacg cgcttcatgt caatggtgaa atcgacgatg 1757581 tcgatgacat tacggcagag caattatacg aaacatacca aagcgctatc caaaaagacc 1757641 agcttgatct atatgttgtt ggcgacgtgg acagtaacca ggtacaatcg gcaattgata 1757701 agtatttcaa aacagaagag cgcactcttg gcatgattga aaacaatcac gctgatgaaa 1757761 aagttcagcc aaaagaagta attgatgaag aggatgtcaa gcaaggaaaa ctgaatatcg 1757821 gctaccgcac cagcatcact tatacagatc aggattatcc tgctttacaa gtgtttaacg 1757881 gattgttcgg cggattctct cattctaaac ttttcattaa tgttcgggaa aaagccagtc 1757941 ttgcttacta cgcggcttcg cgtatagaaa gttttaaagg cttgttaatg gtgatgtcag 1758001 gcattgaagt gaaaaatttt gaacaggcgg tttcgattat tgctgagcaa ttccaggcaa 1758061 tgaaaaatgg cgatttcagt gagcaggata tagcacagac aaaggccgtt attcgaaatc 1758121 aagtgctgga aacgattgat acagcatacg gtttatctga gtttttatat cagcaggccg 1758181 ctgctcaagt cgagattcct atcgaagact ttcttgccaa tattgagaat gtcacaaaag 1758241 aggatatcat taaagccggc gaaaagattc agcttgatac gacttatttc ttaaaaggga 1758301 cggagggtgc atcttgatca aaccaatcga atatgaacag cttcaggaga cgctgtatca 1758361 tgaaaaaatg tccaacggcc ttgatgttta cgttttgccg aaaaaaggct tcaacaagac 1758421 atatgcggtc tttacaacaa agtacggctc gatagataac cggtttgtcc ctttaggtaa 1758481 aaacgagatg gttcacgtgc cggacgggat tgctcacttt cttgagcaca agctgtttga 1758541 gaaagcggac ggagacgttt ttcaagattt cagcaaacag ggggcttctg ccaatgcgtt 1758601 tacgtcattt acaagaacgg cttacctttt ctcaagcaca tcaaatgttg aacgcaattt 1758661 agagacgctt atcgatttcg tacaggaccc atattttact gaaaaaacgg ttgaaaagga 1758721 aaaagggatt atcgggcagg agattaatat gtacgacgat aaccctgatt ggaggcttta 1758781 cttcggggtc attgaaaaca tgtacaaaga gcatcctgtc agaattgaca tagcgggaac 1758841 agtggaaagc atttcacata ttacaaaaga ccttctttat gaatgctatg aaacgtttta 1758901 tcacccgagt aacatgctcc ttttcattgt cggccctgta gatcctgaag cgattatttc 1758961 tcaggtaaga gaaaaccagg ggaaaaagcc gtatactgat cagccggaga tcaaacgaga 1759021 agaagtgaaa gagcaagaag cggttttccg aaaagaaaaa gagatcaaaa tgaacgtgca 1759081 gggaccgaaa tgccttgttg ggctgaaatc caaaaatccg tttaaattag gcaaagagct 1759141 cttaaagcat gaactttcaa tgaacttatt gcttgaagct ctttttggca aaagctctgc 1759201 ccagtatgaa tcactttatg aaaaaggata tattgacgaa acgttcagct ttgattttac 1759261 tgctgaatat gggttcggtt ttgcggcgat cggcggagat acgcctgagc ctgatcaatt 1759321 ggctgaagac atttcaagca tgcttttgcg cgccggtgaa ctgattactg ctgaaaagat 1759381 tgaacttgcc agaaagaaaa agatcggcac attcttaaaa gcgctgaatt cccctgaata 1759441 catcgccaat caatttaccc gttatgcgtt cttggatatg agcctgtttg atgttgtaac 1759501 ggtactcgag cagattaccc tcgaggatgt ccagaacgta atacaagagg aaatcgctgc 1759561 agacagactg actgtctgca aggttgttcc taaatcataa acaaaacatc cctccagtgt 1759621 gaggggtgtt tttctgcgga aagaaggaaa gaggatgaac aaaacagcac taatcaccgg 1759681 agcaagcggc ggcattggca aaagcatcag cgaaaccctt gcagctagag gatacaatct 1759741 gctgctgcat tacaatacaa atcaaaacgc ggcagcggag cttgctgaaa aactaagtca 1759801 gatgtttggc gtaaatgcgg agatattaca agctgacctg tccgcgcaag atggagcaga 1759861 taagctgaca agttcaattg ttcagccgat tgatgcgatt gttttaaaca gcggacgaag 1759921 ccattttggg ctgattacgg atgtagataa cgcaacggtc caggaaatgg ttcagcttca 1759981 tgtggcgagt ccgtatatgc tgacgagaaa ccttctgcca ggcatgattc ggaataaatc 1760041 gggagcgatt gtggctgtca gctcgatttg gggagagact ggagcatcct gtgaagtgtt 1760101 gtacagcatg gcaaaaggag ctcagcattc atttgtaaaa ggattggcta aggagctggc 1760161 gccaagcgga atcagagtaa acgccgtagc gccgggtgca gttgatacaa atatgatgaa 1760221 tcaatttacc ccggctgaaa aagaagagat cgctgatgag attccgatcg gccggctggc 1760281 ccggccgcaa gaaattgcgg atgcaacagc ttttctcctg tctgaaaaag cgtcatatat 1760341 caccggccaa attctgtcgg tgaatggcgg ctggcactgc tgatccgaaa atattcggtg 1760401 tatagtttct tttgcgaagg acacaataat cttgtaactt cacatgaaat ggaggaaaca 1760461 agcatgtcag tattagaaaa ctgggatagc tggaaaaact tccttggcga ccgtctgaac 1760521 tatgcgcaag ataaaggtat gagccaggat acgattacag atcttgcgac agaaatcggc 1760581 agctacttgg ctaatgaagt ggaatctaag aacgagcagg aaaaagtgct ggcagatctt 1760641 tggagtgtag catcaaaaga tgaacagcac gccattgcca atatgatggt taagcttgtt 1760701 gaaaataaca gcactcacta ggaagagagg ggatttttcc tctctttttt atgttttcct 1760761 catcacagca acattcttct ttctaattag agaaaaatgc tttatgataa aggaaggtaa 1760821 aattttgcca caatgaaggg ggtatatcat ttggcaaagc tcgaatggta ttttgaatat 1760881 gaaattcaag tgaaccgccc cggactgctc ggggatattt catctcttct tgggatgctt 1760941 tctatcaaca tcgtaacgat aaacggcgtc gatctttcca gaaggggaat gctcctcagg 1761001 tgccgccata tagatcaaat taaacgatta gaatcaatct taaaaacgat ggaaacaatt 1761061 aaagtaacga agcttagaga accgaggctt cgcgaccgtc ttgccgtacg ccacggccgt 1761121 tatattcaac gggatgccga tgacaagaaa acgttccgct ttgaacggga cgagcttggc 1761181 ttattagtcg attttatggc cgaattgttc aaaaaagaag gccataaatt aatcggaatc 1761241 agaggtatgc cgcgtgtcgg gaaaacggaa tcgattgtag cctctagtgt gtgcgagcaa 1761301 aaggtggctg tttgtgtcat caaccttgct gaagcagacg ataagaagcc agctgattgc 1761361 cgatgaatac agcactgaaa atgtctttat cgttgacgga attgtgtcaa cacgaagagg 1761421 gtcagaacgc catctccagc tggtccgaga aatcatgcgg ctgcctgcaa caaaagtggt 1761481 ggagcatccg gacatattcg ttcaaaatac agagtataca ctagatgact ttgattatat 1761541 tattgaactg agaaatgacc ctgatgaggt tattacatat gaacatgccg aggaacccca 1761601 aatgtttgat caatccgggt tttcaagctt tgatttttaa aattggaagg tgtttgttgt 1761661 gactgaacta ggaatccggc tcaaagaagc cagagaggaa aaagcaatgt cattggatga 1761721 tctccaagcg gcaacaaaga ttcaaaaaag gtatttaacc gccttggagg aaggaaacta 1761781 tgacattatt ccggggaagt tttatgttcg ggcattcatc aagcaatatg cagaagccgt 1761841 tgggcttgat gcggatcagc tgtttgagga gcataaaaaa gatatcccta atacgtatca 1761901 tgatgatgtg tctgaaaaga tctccggcat gaatcttcaa aaggaaatgc caaagccagc 1761961 atctaaggcg ctggagctgc tgccaacaat acttgttatt ctcggcgtga ttgtcgtgat 1762021 tgccattgtg tacgcgatca ttcaatttgc caatcacaaa aacagtgatg atcacaatgc 1762081 ggcatcagaa aaagcaatta cgcaaagtga gagcaagtac gaaatcccta aagattcaac 1762141 gctgaaagag aatcaaaata acagctctga aaaagagaca gacactaaaa aagaaacgaa 1762201 agaaaacgaa gataagaaaa aagaaaatga cagtgagaag ctggagatta aagctgctgg 1762261 cactgaagga tcgttaacga cttatgaagt gtccggcgct gataaaatcg agctggaact 1762321 gaaggcatca gacagctcct ggattagagt gcgcgatgaa aacagcagct ctttaaaaga 1762381 aggaacgctg aaaaaagacg aaacctataa aaaagacata actgatcaga aacaagttga 1762441 tatccgcacc ggatatgcac ctaatctgaa aataaaaatc aacggtaagg ttctttcata 1762501 tgaacttgat ccgaaaaaag tgatggcaca aaccataaag attgtaaata aaaaggaaga 1762561 aaagtcatct taattaccag atgacttttc ttcacgtccg agtatgaaat tggaggggct 1762621 ttatgtttaa cttaccaaat aaaatcacac tagctagaat cgcattaatc ccaatcttca 1762681 tgattatcat gctggcgccg tttgactggg gcaggctcga agttggagac gaatccatcc 1762741 cggtcgcaca tttggcgggg gccattctat ttattattgc atctacaaca gactgggtgg 1762801 acgggtatta tgcccgaaaa ttaaatctcg taacaaactt cgggaaattt cttgatccgc 1762861 ttgcggacaa actgctcgta tccgcagcgt taattatcct tgttcaattt gatctcgctc 1762921 cagcttggat ggtcattgtg attatcagca gggagtttgc cgtgacaggt ttaaggcttg 1762981 tcttagccgg aacaggagaa gtcgtagctg ctaacatgct tggtaaaatc aaaacctggg 1763041 cacagattat tgcggtatct gcattgcttc ttcataatct tccatttgaa cttgtgtcat 1763101 tcccgtttgc agacttggcg ctgtgggtag ccgtcttctt tactgtcgtc tcaggctggg 1763161 aatatttctc taaaaattgg gaagcgttaa aaacatctaa ctaagaaaga aggacttcgt 1763221 catggaattt ccaaaaaaag cagaaataat tgcagtcggt tcagagttgc tgcttggtca 1763281 aatcgccaat acaaatgctc aatttatcag caaacagctc gctgaaatcg gggtcaacgt 1763341 attttatcat acagcggtcg gagataaccc ggagcggctg aagcaggtca tccgcattgc 1763401 tgaagaacgc tctgacttca ttattttttc aggagggctt ggacccacaa aagatgatct 1763461 gacgaaagaa acgattgcaa atacgctggg acgtccgctt gtgttaaatg atgaggcatt 1763521 ccaatccatt gaggactatt tcaaacgaac aaaacgcacg atgtcaccta ataaccgaaa 1763581 acaggcgctt gtgatcgaag gctctgacgt gctggcgaat cactttggaa tggccccggg 1763641 aatgctcaca gagcatgaat cgcgctatta tatgcttctt cctggaccgc cgagcgaatt 1763701 gcgtccaatg tttgaaaacg aggcaaagcc tcttctgctg aaaaagatgg gttcaaatga 1763761 aaaaattgtg tcaactgttc ttcgcttttt cggtatcggt gaatctcagc ttgaagccga 1763821 tttggaagat attattgatg cacaaaccaa tccgacaatt gcgcctttgg cggctgatgg 1763881 agaggtgacg ctgcgtctga cagccaaaca cgccgatgaa aaggaaacag agcgtctgtt 1763941 aaaagaaaca gaggccgtta tcttagagcg tgtcggtgaa tttttctatg gttacgatga 1764001 tacttctctt gtaaaagagc tatctatagc atgtaaggaa aaaggcataa caatttctgc 1764061 ggcagaaagc tttaccggag ggctgttttc tgaatggctg acggatcata gcggtgcctc 1764121 aaaattattt gccgggggcg ttgtttgcta tacaaacgac gtgaagcaga atgtgcttgg 1764181 tgtcaagaag gaaacattag atcgttttgg ggcggtcagc aaggagtgcg catccgaact 1764241 ggctaagggt gttcaaaaac tcactggcag cgatatcggc attagcttta ctggtgtagc 1764301 aggacctgat gctcaagaag ggcatgagcc tgggcatgtg tttatcggca tttccgcaaa 1764361 tggtaaagaa gaggttcacg agtttcactt tgcgggctcc agaacgggga tcagaaaacg 1764421 cggcgctaaa tacggctgcc atttaatctt aaagctttta gagcaaaaat aatattttca 1764481 gcacattatc ctcctaagaa aacatgattt ctctgataca ttatgatatt ttgataggaa 1764541 tcacgccaag aaaaaatccg aatatgcgtt cgcttttttc ttggcaaatc ccttcaaaca 1764601 gggtatagta tatgtagtgg taacataaag gaggaaaaaa tagaatgagt gatcgtcagg 1764661 cagccttaga tatggctctt aaacaaatag aaaaacagtt cggcaaaggt tccattatga 1764721 aactgggaga aaagacagat acaagaattt ctactgtacc aagcggctcc ctcgctcttg 1764781 atacagcact gggaattggc ggatatcctc gcggacggat tattgaagta tacggtcctg 1764841 aaagctcagg taaaacaact gtggcgcttc atgcgattgc tgaagttcag cagcagggcg 1764901 gacaagccgc gtttatcgat gcggagcatg cgttagatcc ggtatacgcg caaaagctcg 1764961 gtgttaacat cgaagagctt ttactgtctc agcctgacac aggcgagcag gcgcttgaaa 1765021 ttgcggaagc attggttcga agcggggcag ttgacattgt cgttgtcgac tctgtagccg 1765081 ctctcgttcc gaaagcggaa attgaaggcg acatgggaga ttcgcatgtc ggtttacaag 1765141 cacgcttaat gtctcaagcg cttcgtaagc tttcaggggc cattaacaaa tcgaagacaa 1765201 tcgcgatttt cattaaccaa attcgtgaaa aagtcggtgt tatgttcggg aacccggaaa 1765261 caacacctgg cggccgtgcg ttgaaattct attcttccgt gcgtcttgaa gtgcgccgtg 1765321 ctgaacagct gaaacaaggc aacgacgtaa tggggaacaa aacgaaaatc aaagtcgtga 1765381 aaaacaaggt ggctccgccg ttccgtacag ccgaggttga cattatgtac ggagaaggca 1765441 tttcaaaaga aggcgaaatc attgatctag gaactgaact tgatatcgtg caaaaaagcg 1765501 gttcatggta ctcttatgaa gaagagcgtc ttggccaagg ccgtgaaaat gcaaaacaat 1765561 tcctgaaaga aaataaagat atcatgctga tgatccagga gcaaattcgc gaacattacg 1765621 gcttggataa taacggagta gtgcagcagc aagctgaaga gacacaagaa gaactcgaat 1765681 ttgaagaata aaaataaaat aagtttcaaa tgatacaaaa ggctgagtga aaaactcagc 1765741 ttttttgtat tttgcaaaaa aatgataaaa atattgcttt ttttgacaac ttttttaggg 1765801 ctttattcgt ctaacaaaac gtgtgcaaaa tggaatttat tttgggagga aaaaatgaat 1765861 gacaagccca acccgcagaa gaactgcgaa acgcagacgg agaaaactaa ataaaagagg 1765921 aaaactgttg tttggtcttt tagcagtgat ggtttgcatt acgatttgga atgctcttca 1765981 tcgaaatagt gaagaaaacg aaccatctca agaaactgca gcggtttcaa ataccgatca 1766041 gaaaaaagag gtcaaaaaga aaactgccaa aaaatcagag gaacaaatca aaacagtgga 1766101 tcgaaaccaa aaaatcagca attatttaaa agagatcggt ttcagcggaa cagccatgat 1766161 tgtcagaaat ggagaaatcg taacaaataa aggttttggc tatgctgacc gtaaacacta 1766221 cattcaaaat aatccattga catcttttta tgtcggttca tcacaaaaag cgctgattgc 1766281 aactgctatt ttgcagcttg aggaaaaggg gaaacttcag acaagtgatc cggtaagcac 1766341 gtatttacct cattttccca acggacaaac gattactttg aagaatctgc ttacacatac 1766401 atcggggata aacggacata ttgaaggaaa cggcgccatt actccggacg atttaataaa 1766461 agatatagaa cttcagggaa tcaaacgtca gccgggcgta tgggactaca aggattccaa 1766521 ctattctgtt cttgcttata ttattgctga agtaagcggt gagccctatg aacagtacat 1766581 aaagaatcat atttttaaac ctgcgggaat gacgcatgca ggcttttaca aaacatatga 1766641 aaaagaacct tatcctgccg tcgggtataa gatggagggc agcaaaacag ttacaccgta 1766701 tatacctgat ttatcccagc tgtatggagc gggtgatatt tatatgagcg ctatagatat 1766761 gtacaaattt gaccaagcgc tgatagacgg aaaactgtat tcgcaaaaaa gctatgaaaa 1766821 gatgtttacg ccagggagca gctccacata cggcatggga ttttatgttg ctcccggaag 1766881 ctattcaaac catggtgtta tgccgggctt caatatcttg aacagcttta gcaaatctgg 1766941 gcaaaccatt gttattttgt tctcaaacat tcaaaataat gctaaattgg gccaagtgaa 1767001 caataaaata taccagcttc taaatcaaga atgattggcg atcttctttt ggatgaattg 1767061 cattcggcac gtgaaaagaa gactggcctg caaacgttaa gatggcaagc ttgacaagta 1767121 tttccgacac atttacaatg aagttgtaac atttgttttt ttaacatgat tgttaaacca 1767181 tttaaacttg acaagggcga tgaacacact cattccctgt gaaggttctg tatgttgaga 1767241 aaactagaca atgtacatgc cgacactttt taagcaacaa ccaagttcat agcaagagga 1767301 ggtgaaagta tgaccccaat tatgatggtt ctcatctcca ttttgctgat tctactcggt 1767361 ttagttgttg gctactttgt tcgtaaaacc attgccgaag cgaaaattgc gggcgcacgc 1767421 ggtgcagccg agcaaattct tgaagatgcg aagcgtgatg ctgaagcact gaaaaaagaa 1767481 gctctgcttg aagcaaagga tgaaatccac aaacttcgaa tagatgctga acaggaagtt 1767541 cgtgaaagac gaaatgagct tcaaaaacaa gaaaaccgtt tactccaaaa ggaggaaaac 1767601 cttgatcgca aacatgaggg aattgataaa cgggaagcga tgttggagaa gaaagatcat 1767661 tctctgaatg aacgacaaca acatattgaa gagatggaaa gcaaagtgga tgagatgatt 1767721 cgtatgcagc agtctgagtt ggaacgaatt tcgagtctga ctcgtgacga agcgaaacaa 1767781 atcattcttg agcgggttga aaacgagctt tcacatgaca tcgccatcat gacaaaagaa 1767841 actgaaaacc gtgcgaaaga agaggcggat aagaaagcga aaaacattct ttcactcgcc 1767901 ttacagcgct gcgcagcgga ccacgttgcc gaaacaacgg tatcagttgt caatcttcca 1767961 aatgatgaga tgaaaggacg tatcatcgga cgggaagggc gtaacattcg tacgcttgaa 1768021 acgctgacag gaattgacct gattattgat gatacgcctg aagctgtcat tctttccgga 1768081 tttgatccga tcagacgtga gacagccaga attgctcttg ataaactcgt tcaggatggc 1768141 cgtattcatc cggcacggat tgaagaaatg gttgaaaaat ctcgccgcga ggtcgatgac 1768201 tatattcgtg agatgggtga gcaaacgaca tttgaggttg gcgttcatgg cctccaccca 1768261 gatctcatca agatcctcgg ccgcttaaag ttccgtacaa gctacggtca aaatgtgctt 1768321 aagcattcca tggaagtcgc attcttggcc ggtctaatgg catcggagct tggtgaagac 1768381 gcaaagcttg ctaaacgtgc gggtcttctt cacgacatcg ggaaagcaat tgaccatgaa 1768441 gtagaaggaa gccacgttga gatcggggta gagcttgcga ccaaatataa agagcaccca 1768501 gtcgtgatta acagtattgc atcacaccac ggggacgagg agccgacttc cattattgct 1768561 gtactggtag ctgcagcaga tgcgctttcc gctgcaagac ctggcgcaag aagtgagacg 1768621 ctcgagaatt atattcgaag acttgaaaaa cttgaagaaa tttctgagtc ctacgaaggt 1768681 gttgaaaaat catttgccat tcaggctgga cgcgaagtgc gaattatggt gaagccggat 1768741 tcaattaatg atcttgaggc tcatcgactg gcgcgagata tccgcaagcg aattgaggac 1768801 gagctcgatt atccaggtca tattaaggtg acagtaatca gagagactcg agccgtagag 1768861 tatgcaaaat aaagtgatgc gctaagcatc actttatttt tttgacggca aggaattttc 1768921 aagaagaaag gatttacaaa atgagaattt tatttatcgg agatgttgtc ggttcaccgg 1768981 gccgtgacat ggtcaaagaa tatgtaccaa agctaaaaac aaaatataag cctcacttta 1769041 ccattattaa tggtgaaaac gccgcacatg gaaaaggcct gacggaaaaa atttatcaca 1769101 gcttaatcca gtccggcgca gatgcaatca caatggggaa ccacacatgg gacaaaaaag 1769161 aaatatttga ttttatagat gacgttccga acttggttcg cccggcaaac tttcctgaag 1769221 gaacaccggg gaaagggatc acatatgtga aagcaaacgg caaagaacta gcagtcatta 1769281 atttgcaggg acgtacgttt ttgccgccgc ttgatgaccc gtttttaaaa gcggatgaat 1769341 tgatcgcaga agctgcgaaa agaacaccgt acatttttat tgactttcat gccgaagcga 1769401 caagtgaaaa gctcgcactt ggctggtaca cggatggacg ggcatcggct gtagtaggaa 1769461 ctcatacaca cgtgcaaaca gcggataacc gcattttgcc gaagggaacg gcatatatta 1769521 ctgatgtggg aatgactggc ccgtatgacg gtatactggg gatggacaga gagacgatta 1769581 ttaagcgatt caaaacgaac cttccagtcc ggtttactgt cgctgaagga aaaacaacgc 1769641 tcagcggagt tgtcattgac attgacgatc aaacgaaaaa agccgtgaaa attgagcgta 1769701 ttttaatcaa cgatgatcac atgttctttg aatagttgaa catatggtta ttttataaaa 1769761 atattaaaaa gaaaagcagg aatatagcaa ctccttagtg aatatagtaa aaatggaagg 1769821 tagcccgcta tttttgaaaa gcattgtggg gatggctttt tggatagcaa catctaataa 1769881 tgattgttct aatgaacact cacttatcca ttgtaaaact aagggggagc agaaatggaa 1769941 atcttaaaag tttcagcaaa atcgagtcca aattcagtgg caggtgcgct tgcaggcgtg 1770001 ttgagagagc gaggagccgc cgagattcaa gcgatcggag cgggtgcatt aaaccaggct 1770061 gtaaaagctg tggcgattgc caggggattt gtggcgccaa gcggcgttga tttgatttgt 1770121 attccggctt ttacagatat tcaaatcgat ggggaagaaa gaacagcgat taaattaatc 1770181 gtggagcctc gctaaaaaca aataaagcat tctcaacctg tttgcgtaat gcaaacaggt 1770241 tgtttttcat ttattgtgat attttctccc gatagtattt ttagcacata aatgagcgaa 1770301 tatacaaaat cagaaatgag ctaaaacgtt tcaaaaaaaa tttccgccca tttttcaaga 1770361 cagatacttt tgtccttctg gaaaagacag ttctgtttac gcttattcca tatcatggta 1770421 caatccgaat ataacaagaa tttttcaagg aggattgtac atgcagagtg gaaagatgaa 1770481 agctctaatg aaaaaggacg gggcgttcgg tgctgtgctg actgaagttc ccattcctga 1770541 gattgataaa catgaagtcc tcataaaagt gaaagccgct tccatatgcg gcacggatgt 1770601 ccacatttat aattgggatc aatgggcacg tcagagaatc aaaacaccct atgttttcgg 1770661 ccatgagttc agcggcatcg tagagggcgt gggagagaat gtcagcagtg taaaagtggg 1770721 agagtatgtg tctgcggaaa cacacattgt ctgtggtgaa tgtgtccctt gcctaacagg 1770781 aaaatctcat gtgtgtacca atactgctat aatcggagtg gacacggcag gctgttttgc 1770841 ggagtatgta aaagttccag ctgataacat ttggagaaat cccgctgata tggacccgtc 1770901 gattgcttcc attcaagagc ctttaggaaa tgcagttcat accgtactcg agagccagcc 1770961 tgcaggagga acgactgcag tcattggatg cggaccgatt ggtcttatgg ctgttgcggt 1771021 tgcaaaagca gcaggagctt ctcaggtgat agcgattgat aagaatgaat acaggctgag 1771081 gcttgcaaaa caaatgggag cgacttgtac tgtttctatt gaaaaagaag acccgctcaa 1771141 aattgtaagc gctttaacga gtggagaagg agcagatctt gtttgtgaga tgtcgggcca 1771201 tccctcagcg attgcccaag gtcttgcgat ggctgcgaat ggcggaagat ttcatattct 1771261 cagcttgccg gaacatccgg tgacaattga tttgacgaat aaagtggtat ttaaagggct 1771321 taccatccaa ggaatcacag gaagaaaaat gttttcaaca tggcgccagg tgtctcagtt 1771381 gatcagttca aacatgatcg atcttgcacc tgttattacc catcagtttc cattagagga 1771441 gtttgaaaaa ggtttcgaac tgatgagaag cgggcagtgc ggaaaagtaa ttttaattcc 1771501 ataaaggggg ataaacatga cgaaggaatt tgagttttta aaagcagagc ttaatagtat 1771561 gaaagaaaac catacatggc aagacataaa acagcttgaa tctatgcagg gcccatctgt 1771621 cacagtgaat caccaaaaag tcattcagct atcttctaat aattacctcg gattcacttc 1771681 acatcctaga ctcatcaacg ccgcacagga ggccgttcag cagtatggag ccggcaccgg 1771741 atcagtgaga acgattgcgg gtacatttac aatgcatcaa gagcttgaga aaaagctggc 1771801 agcctttaaa aaaacggagg cggcacttgt attccaatca ggcttcacaa caaaccaagg 1771861 cgtactttca agtattctat caaaagagga cattgtcatc tcagatgaat tgaaccatgc 1771921 ctctattatt gacggaattc gactgacaaa ggcggataaa aaggtgtatc agcacgtcaa 1771981 tatgagtgat ttagagcggg tgctgagaaa gtcaatgaat tatcggatgc gtctgattgt 1772041 gacagacggc gtattttcca tggatggcaa catagctcct ctgcctgata ttgtagagct 1772101 cgctgagaaa tatgacgcat ttgtgatggt ggatgacgcc catgcatccg gagtacttgg 1772161 cgaaaacggc aggggaacgg tgaatcactt cggtcttgac ggcagagtgc atattcaggt 1772221 cggaacatta agcaaggcaa tcggagtgct cggcggctac gctgcaggtt caaaggtgct 1772281 gatcgattat ttgcgccata aaggccgtcc atttttattc agcacatctc atccgccggc 1772341 agtcactgca gcttgtatgg aagcgattga tgtcttgctt gaagagccgg agcatatgga 1772401 gcgcttgtgg gagaatactg cctattttaa agcaatgctt gtgaaaatgg gtctgactct 1772461 cacgaagagt gaaacgccga ttcttcctat tttaataggt gatgaaggtg tggcaaagca 1772521 attttcagat cagctccttt ctcgcggtgt ttttgcccaa agtatcgttt tcccgactgt 1772581 agcaaaggga aaagccagaa ttcgcacgat tataacagca gagcacacca aagatgaact 1772641 ggatcaggcg cttgatgtca tcgaaaagac ggcaaaggag ctccagctat tgtaacaaga 1772701 ggaagagttt actcttcctc ttttgattcc ttattgatta ttattctcaa tgagtgtaca 1772761 atgataggtt gccagttgtg cagagcttca ataaccttta tactgaaggg tggaagtttg 1772821 gtttgaaagg agaaaatatg acatgaatga aaaacaaaaa ttagagagcg gacaagttca 1772881 tccatcggac aaaaaatccg agaaggatta cagcaagtac tttgaagctg tttacattcc 1772941 gccttcttta aaagacgcga aaaaacgagg caaggaagcc gttacttatc ataatgactt 1773001 taaaatttct gaacaattta aaggattggg agacggaaga aagttctata tccgtacgta 1773061 cggctgccaa atgaatgaac acgatacaga ggttatggca gggatcttta tggcgctcgg 1773121 ttacgaagcg acaaactctg ttgacgatgc caatgtcatt ttgttaaata catgtgcaat 1773181 ccgtgaaaat gctgaaaaca aggtgtttgg tgagctcggg cacttaaaag cactgaaaaa 1773241 aaacaatccc gatctgattt taggcgtgtg cggctgtatg tcccaagagg aatcagtcgt 1773301 gaaccgtatt ttgaaaaaac atccgtttgt cgatatgatt ttcggaacgc ataacattca 1773361 tcgcctgccg gagcttttgt cagaagcata cctttcaaaa gaaatggttg tagaagtttg 1773421 gtctaaggaa ggggacgtta ttgaaaacct tccaaaagtc cgaaatggaa aaattaaggg 1773481 ctgggtcaat atcatgtacg gctgtgacaa attctgtacg tattgcattg tgccttacac 1773541 acgcggaaaa gaaagaagcc gccgccctga ggatatcatt caggaagtga gaaggctcgc 1773601 aagtgaaggc tataaggaaa ttactctgtt aggccaaaac gtaaacgcgt atggaaaaga 1773661 ctttgaagat atgacgtacg gacttggtga tttgatggat gaactgagaa aaatcgatat 1773721 cccgagaatc cgttttacaa cgagtcatcc gcgcgacttt gacgaccgcc tcattgaagt 1773781 gctggcaaaa ggcggaaatc tgcttgatca cattcatctt ccggttcaat caggaagctc 1773841 agaagttctc aagctgatgg cccgcaaata tgacagagag cgttacatgg agctggtgcg 1773901 aaaaattaaa gaagcaatgc caaacgcttc tttgacaacg gacattatcg tcggatttcc 1773961 aaatgaaacg gacgaacagt ttgaagaaac gctttctcta taccgtgaag tggagtttga 1774021 cagcgcctat acgttcattt actctccgcg tgaaggcact ccggctgcta agatgaaaga 1774081 taatgtaccg atgcgtgtga aaaaagaacg cctgcagcgt ctaaacgcac tggtgaatga 1774141 aatttctgct aaaaaaatga aggaatacga aggcaaggtt gtcgaagtat tagttgaggg 1774201 tgaaagcaaa aataaccctg atattcttgc tggctatact gaaaaaagca agcttgtcaa 1774261 tttcaaaggg ccgaaggaag ccatcggcaa aatcgtccgc gtgaaaatcc agcaagcgaa 1774321 aacatggtcg cttgacggag aaatggtagg agaagcaatc gaggtgaaat gagatgacgc 1774381 tctactcaaa aaaagacatt gtgcagcagg ctcgaaacct tgcaaaaatg atttctgaaa 1774441 cagaagaggt tgattttttc aaacgggctg aagcgcaaat caatgagaat gacaaagtgt 1774501 ccacaatcgt taatcagatt aaagccctgc aaaagcaggc tgtcaatctg aagcattatg 1774561 aaaagcatga agcgctcaaa caagtagaag caaaaattga cgcgctgcaa gaagagcttg 1774621 aagagattcc tgttatccag gaattcagag actcgcaaat ggaagtaaat gacctactgc 1774681 agctcgttgc acacaccatt tccaaccaag tcacaaatga aatcatcaca tcaaccggag 1774741 gcgacctgct gaaaggggaa accggttcaa aggtgaagca ttcaaataac agctgttctc 1774801 tctaaacacg gtgcctttac aggcccgtgt ttttttatca tttgtgcggt taaaaatgaa 1774861 ctaaataatc tatgtaccaa atgttcaatt ggtttttctg tgctcagccg cgtataaact 1774921 ttatcgcact tataagtaaa gtttctaggc acccctgcat acaatggaac agaaactttg 1774981 tatttttata ttttatttat aaaaatgcac actagacaaa tgcccagcat aagataacac 1775041 gaagaagaac aaggaggcat gccggaatgt ctgaatacag ggaaattatt acgaaggcag 1775101 tagtagcgaa aggccgaaaa ttcacccaat gcaccaacac catctcgcct gagaaaaaac 1775161 cgagcagcat tttgggtggt tggattatta accacaagta tgacgctgaa aaaattggaa 1775221 aaacggtaga aattgaaggg tattatgata taaacgtatg gtactcttac gcggacaaca 1775281 caaagacaga ggttgtcaca gaacgggtaa aatatgtaga tgtcattaaa ctcagataca 1775341 gagacaataa ttacttagat gatgagcatg aagtgattgc caaagtgctt cagcagccaa 1775401 actgccttga agtgaccatt tcgccgaatg gaaataaaat cgttgtgcag gcagaaagag 1775461 aatttttggc ggaagtggta ggggaaacaa aggtagttgt tgaggtcaat cctgactggg 1775521 aagaggatga cgaggaagat tgggaagatg agcttgatga agagcttgaa gacatcaacc 1775581 cggagttttt agtgggagat cctgaagaat aaaaaaggga ctaggggaga cagtaccccc 1775641 aagtctcttt tttatattga tatatcattc ttttatcact ttttgtttat gttataatga 1775701 aggttggaaa atagaaacgt tgatacatag tgagggatta aacaatggcc ggttatacgc 1775761 ctatgataca gcaatattta aaaataaagg cagagcacca ggatgccttt ttattttttc 1775821 gcctgggtga tttttatgaa atgttttttg aggacgccaa aaaagcgtca caagagctgg 1775881 aaattacgtt aacgagcaga gacggcggtg cggctgaaaa aataccgatg tgcggtgtgc 1775941 cgtatcattc tgcttccgcg tatatcgaac agcttattaa aaaaggatac aaagtggcga 1776001 tctgtgaaca gacggaagat ccgaaagccg caaagggcgt tgtgaaaaga gaagtagttc 1776061 agctgattac gcccggaact gtaatggacg gcaaaggcat ccatgagtcg gaaaataatt 1776121 ttatcgcatc tgtttcagcc tgctcgaacg gatacggact tgctctgtct gatttaacaa 1776181 cgggagaaaa tttggctgtt ttgattgaac ggcttgaaga cgtcatatca gaaatttatt 1776241 cagtcggcgc acgggaaatc gtggtttcag gaagcttgga tgccgataca gtggcacagc 1776301 tgagagagcg gtgcggtgca acgatttcaa ttgaagacgg agaaacagac gaacacgtaa 1776361 cgatcattga gcacttaaat aatgaagata taacaaaaac atttctgcgc ttatatacgt 1776421 atttgaaaag aacccaaaag cgcagccttg atcatcttca gcccgtgcag gtgtatgagc 1776481 ttgaggaagc gatgaaaatt gacttgtact caaagcgtaa tctggagctg accgaaacga 1776541 ttcgttcgaa aaataaaaaa ggctcccttt tgtggctgct ggatgaaaca aaaacggcaa 1776601 tgggaggccg gctacttaaa cagtggattg accggccgct tatcagagtc aatcaaatcg 1776661 aagagcgcca agaaatggtg gaaacattaa tgtcccattt ctttgaacgg gaagatctgc 1776721 gtgaacgttt aaaagaagta tatgacttag aacgccttgc cggccgcgtt gcattcggaa 1776781 atgtcaatgc ccgggatttg attcagctga aggaatcgtt aaagcaagtg cctggcatca 1776841 aacagctggt tgcttcactg gctcatgaca aggccaagga acgtgcaaag cgcattgacc 1776901 cttgcgggga tgtacttgaa ctgctggaag aagcgctgta cgaaaaccct cctttatcgg 1776961 taaaagaagg gaacctgatt aaagatggtt ataatcaaaa gcttgatgaa tatcgtgatg 1777021 caagcagaaa cggaaaagac tggattgccc gcctggaaca gcaggagcgg gaatacacag 1777081 gcattcgctc tttaaaggtc ggctttaata aagttttcgg ttattacatt gaagtgacaa 1777141 aagcaaactt gcatttgctt gaggaagggc gttatgagcg gaagcagacg ttaaccaatg 1777201 cagagcgcta cattacacct gaattaaaag aaaaagaagc gctcatttta gaggcggaaa 1777261 ataacatctg tgagctggag tacgagctgt ttaccgagct gcgcgagaaa gtgaagcagt 1777321 atattccgcg gctgcagcag cttgcaaaac agatgagcga gctggacgca ctgcaatgct 1777381 ttgcgacaat cagtgaaaat cgccactaca cgaaaccaga gttctctaaa gatgaagtcg 1777441 aagtgattga aggcagacac ccggttgttg aaaaagtcat ggacagccag gaatatgtcc 1777501 cgaacaactg tatgatgggc gataacagac aaatgcttct cattacaggt ccaaacatgt 1777561 cagggaaaag cacgtatatg agacaaatcg cgctcatttc cattatggcg caaatcggct 1777621 gctttgtacc cgcgaaaaaa gcggtgctcc cgattttcga tcaaattttt acgcgaatcg 1777681 gcgctgcaga tgatttgatt tccggacaaa gtacatttat ggtagaaatg cttgaagcga 1777741 aaaatgcgat tgtcaatgcg acgaaaaaca gcctcattct gtttgatgaa atcgggcggg 1777801 gaacgtccac ttatgacggc atggcgctgg cacaggcgat tattgaatat gttcacgatc 1777861 atatcggcgc caagacgctg ttcagcacac actatcacga gctgaccgtt cttgaggaca 1777921 agctgcccca gctgaaaaac gttcatgttc gcgctgaaga atataacgga acggttgtct 1777981 ttcttcatca aattaaagaa ggtgcggctg ataaaagcta tggtatccat gtagctcagc 1778041 ttgccgaact gccgggagat ctgattgcgc gcgctcaaga tattttaaaa gagcttgagc 1778101 attcaggaaa caaaccggaa gtgccggtgc agaaacctca ggtgaaagaa gagccggcac 1778161 agctgtcctt ttttgacgaa gcggaaaagc cggctgaaac accaaagctt tcaaaaaaag 1778221 aaaagcaagt gatcgatgct ttcaaatcac ttaatatact ggatatgaca ccgcttgaag 1778281 cgatgaatga aatgtacaag ctgcaaaaga aattacatta aaacggggtg atgaatgtgg 1778341 caaaagtcat ccaactgtca gatgagcttt caaataaaat agcggcgggc gaggttgtgg 1778401 aacggcccgc ctcagtcgtc aaagaattgg tggaaaatgc gatcgacgct gacagcacag 1778461 tcattgaaat cgatattgag gaagcaggcc ttgcatccat tcgggtcttg gataacggcg 1778521 aaggaatgga gaatgaagat tgcaagcgag ctttccggcg ccacgcaacg agtaaaataa 1778581 aagatgaaaa tgatttattc agggtgagaa cgctcggttt caggggagaa gccctgccga 1778641 gtatcgcgtc agtctctcat ctggagatta caacaagcac tggtgaagga gctgggacga 1778701 agctcgtcct ccaaggagga aacatcattt ccgaatcgcg ttcctcaagc aggaagggaa 1778761 ctgaaattgt cgtttccaac ctgtttttta acacaccggc ccgtttgaaa tatatgaaaa 1778821 ccgttcatac agagcttgga aacattacag atgtggttaa ccgtattgct ctggcgcatc 1778881 cagaggtatc gatccgcctg cgccatcatg ggaaaaacct gcttcaaacg aacggaaacg 1778941 gagatgtgcg ccatgtactg gcagcgattt acggcacggc tgtcgccaaa aaaatgcttc 1779001 cgctgcatgt gagctccttg gattttgaag taaagggata tatcgccctc ccagagatta 1779061 cacgggcgtc gagaaactat atgtcgtctg tggtcaatgg ccgttacatt aaaaatttcc 1779121 cgctcgtcaa agcggttcat gaaggctatc atacgcttct gccgatcgga cgccatccga 1779181 ttacttttat agaaattacg atggacccga ttttagtcga tgtcaacgtg catccatcga 1779241 agcttgaggt ccggctcagc aaggaaacag agcttcatga cttaatacgt gacggaatta 1779301 aagatgtgtt taaacagcag cagctgattc ctagtgccca ggtcccgaaa aaatcagcac 1779361 ctgccatcaa aaatgagcag cagtttataa cctttgatga aaagcctccg gaaaaaaaag 1779421 ttccggaaaa atcgactgcg ccatcttatt caccgatgaa gctcagctca gtcgtaaaag 1779481 agccggttga tgcggaggaa aaattgcccc ctctccaatt tgatgctcct cctatcgttg 1779541 atcaggaaca aacccttgag gtgtccgatg tttcagcaga acagcctgaa acatttgagc 1779601 aggaatgcca tgaggaacag ccgcagccag cgtctgatcg ggttccaatt atgtacccga 1779661 ttggccagat gcacgggact tatatattgg cacaaaacga aaacggccta tatattatcg 1779721 accagcacgc cgcccaagaa cgtattaaat atgagtactt ccgtgaaaag gtgggggagg 1779781 ttgagcctga ggtgcaggag atgattgtac cgctgacgtt ccactactcc acaaatgagg 1779841 ctttgattat tgaacagcac aaacaagagc tcgaaagcgt cggtgtcttt ttagagtcat 1779901 tcggctctaa cagttacatc gtccgctgcc acccagcctg gtttccaaag ggagaagaag 1779961 cagagcttat agaagaaatc attcagcagg tgctcgactc caaaaatata gatattaaaa 1780021 aacttcgcga ggaagcggcg attatgatga gctgcaaagg ctccatcaaa gcaaatcgcc 1780081 acctcagaaa cgacgaaatc aaagcgcttc tggacgacct ccgaagcaca tcagacccat 1780141 ttacatgccc gcacggccgc ccgatcatca ttcaccactc gacatatgag atggaaaaga 1780201 tgttcaaacg cgtgatgtag cgggggtggt aggcattgat ccattctctg aatggatcaa 1780261 tgcttttttt gtactccttc gagtgtcaga ttataagaaa cggttgtaaa cgtgtgagca 1780321 gtgttaacgc attatacttc atggttcctc cgtataacaa aatttccatt tacaggcaat 1780381 tgggattaat gtatattttg ggtgaggggg tggaaacata tggcatgtgg tccgaagatc 1780441 attatctttt tggatgaact tgatgatcca aatgtgagaa tcattttaga atgcagaatt 1780501 taaattacaa cattgtgttt tgctccctgt tcgtgtgaac agggagattt tttcgtttat 1780561 ataactggtg atgtccaaat atagggtgtt atgaattttc catatctgcc atcggcttta 1780621 agctgcttct ctattaggct ggttatcaaa agcaagttca atgatagcca tgaaagctga 1780681 tatcacaaca agcaagacat ctggaatata aatagactgc ataaagtaat ctgcaaaaca 1780741 gatcgttata agattgctga taaaatacag tataaaagca aaaagtgcag tctttttcaa 1780801 tgaaagtgat tttgccaaaa tgatagagat aatctttgtg agtgggtcta tgattaaacc 1780861 tacagcaaag caggctaaaa taaataaagc taatgtttga ttggaagcgt atgtgatgcc 1780921 aagtatggag aataagcctt tcatcccgaa gaaaaagccg ccgaagatga ctgcaagcgc 1780981 gatggccgcg ataaaagtaa tagatacaat tccgattaat tttgatctca ggttaaaatc 1781041 tttagagtgc tcgttctgtt ctttttggtt catgtatgac actcccttca cctgcttact 1781101 catacaaaca gcacccttga atcagcccaa aatatctata agtctgtttt ctgacgaaaa 1781161 tagtatagca tattttaaca aaaccaaaaa aggccctttc cactggggaa gggccttttt 1781221 catcatgtta actcctgaga ttcgccgaag ctttctcttt ttttggccaa ataaaatagc 1781281 tggctgtaat gagaaagtca atgcctataa tgacagtcca cagtttaaga atgccgctca 1781341 acgcctcggt tcgggaagag tcattgataa aatagatcat ccctgccaat agtcccgcac 1781401 caattaagta ggccagcaca tgtcttagcc agcctttcgc accgtgcttg gcatggtcca 1781461 ttccaaaacg tttcagcggt tttgttcctt tttttgtcac ataatattga aacttttcat 1781521 ctgcccattg aatcatttgt ttcccataag cgatcgatat accgatgtaa acagctgcaa 1781581 tcccatgggc tgcggtcgct gaggctccgc ggtaaaggtc cacaccagtt gccgctaaca 1781641 agatcaaatc gataactgga gttaaggcaa ggaatagcag tcctaatgta tgtcgtttga 1781701 atacgtagcg tacagcaagc cccaaaacaa tgacaaccca aaacgcaatt tcacagaaaa 1781761 caatcatcca tgcgataccg ttcaatccat tcccctcttt tcaatacagt tgtattattt 1781821 aaataatatg ttaccatctt tgtttttgta acacaactgt attataaaaa ttgccctctc 1781881 atttttttct tgttacaata aagctatgcc aaaacaaatt gaccatgaga aaagaagaaa 1781941 acaaattgca gaagcaacgt ggcgcgtcat tttagaacga gggatggagg gagcatcagc 1782001 cagaaatatt gcaaaggaag caggattgtc attaggtgcg ctgcgccatt atttctctac 1782061 acaggatgaa ttgcttgctt ttgcaatgaa acttgtccaa gaaaaggtaa cggaccgaat 1782121 taaggacatt gcagtgaggg atttgctccc taaggaaaaa gtgttgcaaa ttttgcttga 1782181 aatggtccca acgaatgaag aaacgattag agagatggag gtttggtttg cttttactgc 1782241 ttacgccaga cataaaaagg atatgtttga tgcgagtcat gacgggattt tcagcggcat 1782301 gcggaatctg attgcctatt tagatgaatc cgatttactg aagcagaatg ctgataaaga 1782361 cattgaagct gagagacttt acgcgcttgt tgacggcttg gctttacatg ccatgcttga 1782421 ccctgtgcgc gtgaataaag accgaatcaa gcgggtcatt atgcagcatg tagagtcaat 1782481 ttgcgtggaa gatacacgtg agacacaaaa acgacatcct taaggcacta gtgtgaaaag 1782541 cgattcttgt tgggcatgcg tccaaaagag tcgctttttt attttcaaag aacaaggatc 1782601 tctgaaaaaa atggaaaaca atcatgctgt ttggtaaagt ggaatgaaag acggactgag 1782661 gggtgaacac tggtccatcg tttaagaact ttacatgata gggatggtat aaatgaatct 1782721 tacttacaag gtgcatccaa ttaaaacaag gtatcagggc tggacgaatt attgctatat 1782781 cattgaagat attgtaagca gatctgcaat tgttgttgat ccctcatggg aattgagtaa 1782841 gataaccact acactttccg aactcgaagc ggaattaaag gcagtcgcat tgacacactc 1782901 tcattatgat catgtaaatc tggtagaccc gctgacgaag atgtttaacg ctcaagttta 1782961 tatgtcgaaa aaagaaattg attattatca attccgatgc agaaatttaa ttagcctaga 1783021 tgatcatcag acgatcagca taggaaacac aagagcacag tgccttctca caccggggca 1783081 tacagccggc ggaatgtgtt atttgttttc tgagagtatt tttaccggag atacggtgtt 1783141 tacagaaggg tgcggcatat gtgaggatga tggcagctct gcggaagaga tgtttgatag 1783201 cattcaaaga ataaagtcgg aggtttcacc ccatgtacgg gtgtatcctg gtcactcatt 1783261 tggcaaatcg cccggccatt cgataaagga tctttatcag cataatattt actttcaaat 1783321 tgataagaaa gaatattttg tgaaatttcg cactcgtaaa aaccaaaaag gtatttttga 1783381 ttttaaataa tccttctgaa tctattatcc tatttttctt cgaatatcta aatgattttt 1783441 attttcgaaa atgattacat agaaggtgtt atttattttg aaaactcatt tgaaagaaaa 1783501 tgaagcgcat tatcatgata tggcgcccta tatgtaatcc gggtcttttt tcttatgttc 1783561 tgttatatct cctgatcctt tattcctcaa tggaaaaaag cagaaaaaca atggagcaaa 1783621 ctgtaggaaa aattaacttg acggataata tttacagagg ttaccatcaa catgaacatg 1783681 ctactattta tccggtcatc actattataa aatcatacag aagtgaaaca catctactaa 1783741 tcggaagggt ggctttgaga gaatgatcac atatgttttt ccaggtcagg gttcacaaaa 1783801 acagggaatg ggcagcggcc tattcgatga atttaaagaa ctgacggatc aggcagatga 1783861 gatcttagga tattctatca aacgtctttg cctggaaaat ccttattcca atttaaacaa 1783921 aacgcaattt actcagccgg cattatatgt ggtaaacgca ctaagctatc tgaaaaaaat 1783981 cagggatgaa gaagttaaac ctgactttgt cgccgggcac agcttgggtg aatacaatgc 1784041 gttatttgca gctgaagcct ttgattttga gacaggttta cagcttgtca gaaaaagagg 1784101 cgagctgatg agtctgataa gcaacggcgg tatggcagct gttatgggac taaatgaaga 1784161 gcaggttgca aaggctctga aagaatatca tttacatgat gttgatatcg ctaatgtgaa 1784221 tgccccatat caaattgtaa tttcaggaaa aaaagatgag attgaaaaag ccgcatctct 1784281 ttttgaaacg atgactgaag ttacaatggt actcccctta aacgtaagcg gcgcgtttca 1784341 ttccagatac atgaataaag caaaagaaga attcgaggag ttccttcatg ccttttattt 1784401 ttcgcctccg tctatcccgg ttatttctaa tgtgtatgcc aaaccgtata catacgaatt 1784461 catgaaacag acgctggctg atcaaattaa tcattcagtg aaatggactg acagcataag 1784521 ctacttaatg aaaaaaggcc atatggagtt tgaggaggta gggcctggaa atgttttaac 1784581 tgggttaatt catcgcataa agaaagatgc ggaagcaatg ccccgctaaa gcatttgccc 1784641 ctatggccat gtatctcatc aatcaggtct aaacacagat ttcctttcat ttaaggtata 1784701 aagttttaaa gattcaatcg ttcgattgac actgtttcta attgaataac tttatatact 1784761 gttacataaa gaggctgata aattaagtta gacatttgaa ctatgtcagc cggtctgtca 1784821 aaccatcgct cccacatcta gatggtccat ttttaaaccg cacccaccaa tcatagagtc 1784881 gatgttcttt gctgatcctg ttatcatgtt acatcaattt tgagatatca acatacatct 1784941 acgatcacgt cataaatgaa ccacatccag agcaccaata gcaatccttc caagttgaat 1785001 ctcctttact ttttcacata tgtcttttcc atttattaat ttcatttcaa tcgctgctat 1785061 gtgctttaac aacatgcatg gaaatgagaa atccaatagc cgtcataaat ataaaaaaag 1785121 aaggttatac acatgaatga accgcttgtt tttatgtttt ccgggcaagg ttcccaatac 1785181 tatcacatgg ggaaagaact atttaaggaa aataccgtgt ttcgccaatc aatgcttgaa 1785241 atggatgcca ttgcagcacg gcgaatcggc acatccattg ttgaagaaat ctaccatcca 1785301 ggtaaacgtg tgtcagatcc gtttgacagt attctttttt cccaccccgc catttttatg 1785361 attgagtatt ccttatataa ggttttggaa gacaggggaa tttatcctga ttacgtattg 1785421 ggatcaagtc tgggagaatt cgcagcagcg gcagtttctg gtgtgtcaga cgcagaggat 1785481 atgctggatt gcatacttga acaggctatt atcatccaga attcctgcga taaaggaaaa 1785541 atgctggcca ttcttgacaa accgcaattg ctgaatgatc atccgcaact gtttggaaat 1785601 agtgaactca tttctatcaa ttatgattcg cacttcgtca tttctggtga agaagatcat 1785661 ataaggaaga ttatggagga tttaaaggag aagcagattc tttgccagct gcttcctgtg 1785721 tcctatgcct ttcattcttc gcttattgat ccggcagaga gtgcctatgc agaattttta 1785781 agatcaaaat cttttcaaaa accgtcaata ccgattgtat cgagcttaac gggaagctgc 1785841 cttcacgtaa tggacgagaa tttcttttgg aatgcggtca gaaagccaat gatgtttcgt 1785901 gaagcgattc gatatttgga aagccagcat acatgcaagt ttatcgattt agggccatcc 1785961 ggcaccttag ctgcttttgt gaaacagctg attccgggtg attcagctga ccgttgctgc 1786021 tcaatcataa caccatttca tcaggagctg aaaaatctga atacggttga gtatttccgt 1786081 acaccagaaa ggaagtttac aagatgatta catatgtctt tccagggcaa ggctcccagc 1786141 aaaaggggat gggacaaggg ctatttgaac agtatcagca tttgacagat caagcagatc 1786201 aaatattggg ctattcaata gagaagctat gtaccgaaaa atcatatctg gatgtaaatc 1786261 atactgaata cacgcagccg gctttgtatg ttgttaatgc actcagttac ttgaagagag 1786321 tggaggagac cggcagaaaa cctgattttg cggcaggaca cagcttagga gaatacaatg 1786381 cgctgatggc agccggtgca tttgattttg aaaccggatt aaggctcgtc aaaaaaagag 1786441 gagaattgat gggacgaatt acagggggcg gaatggctgc tgtgatcggc ctgagtaagg 1786501 aacaagttac agccgtttta gaagagcacc gtctttatga cattgatgtg gcaaatgaaa 1786561 atacgcccca gcaaattgtg atttctggcc cgaaaaaaga gattgaaaaa gctcgggctg 1786621 tttttgaaaa caccaaggat gtaaagctgt ttcatccatt aaatgtgagc ggagcttttc 1786681 attccagata tatgaatgaa gccaaacagg tatttaagca atatattgac tcattccagt 1786741 ttgcaccttt ggcgatcccg gttatctcca atgtctacgc agagccatac catcaagaca 1786801 gattaaaaga tacattatct gaacaaatgg acaacacagt gaaatggacg gacagcattc 1786861 gttttctgat gggaagagga gaaatggagt ttgcagagat tgggcctgga actgttttaa 1786921 ccggtctcat tcatcggatt aaaaatgaag ctgaaccatt gacatatata ccgaaaaaga 1786981 accccgcgat cagtgcgcat ctaaaggagc aacgcaatgt tcaagccggg attacggcag 1787041 aatctttagg aagtgctgaa tttaaacaag attatcatct tacatatgct tatcttgcag 1787101 gaggaatgta ccgcggcatt gcttcgaaag aaatggtagt aaagctgtca agagcgggaa 1787161 tgatggggtt ctttggcaca ggaggtctga gcctgaaaga ggttgaagat gcgatccatg 1787221 ctatacaagg tgaattagga aaaggacaag cctacggcat caatctggtc cacaatatga 1787281 aacatactga atcagaagaa aaaatgatcg atcttttatt gaggaatcaa gtgagcattg 1787341 tggaggcttc agcattttta agtgtcactc ctgtattagt aaggtatcgc gcaaaaggag 1787401 tgaaacgaaa tcaaaatggt gacgttatat gctcaaatcg tctcatagca aaaatatcac 1787461 ggccggaagt tgcagaatca tttctgagtc ctgcgcctga gaatatgctg caaaagcttt 1787521 taggagaaaa taaaatcact atgaacgaag ctgagttgtt gcggtgcatt ccgatggctg 1787581 acgatatttg tgtagaagct gattcaggcg gtcatacaga tggcggtgtg gcatacagcc 1787641 tgatgccggc gatgacatct ttaagagatg aaatgatgaa aaaatatcaa taccggaaaa 1787701 aaataagagt tggtgcagct ggaggaattg gaacacctga ggcagcgatg gcggctttta 1787761 tgctaggggc tgattttatt ctaacaggct caatcaatca atgtacggtt gaggcggcaa 1787821 caagtgataa agtaaaggat ttgcttcagc agatgaatgt acaagataca gcctatgcgc 1787881 ctgcaggtga tatgtttgaa tcgggcagta aagtgcaggt gctaaagaaa ggcgtgttct 1787941 ttcccgcacg ggcaaacaag ttatatgaac tgtatcagcg gtatgggtct atacgtgagc 1788001 tggatgcaaa gatgctggcc cagcttgagg agaaatactt taaacgcagt atagaagaca 1788061 tatataaaga tattgcattg cattatcccg cggcagacat tgagaaggct gaacaaaacc 1788121 cgaagcataa aatggctttg attttccgat ggtacttcag atacagttca aaattggcaa 1788181 tcagcggaag cgaacattcg aaggtcgatt atcaaattca ctgcggtccc gcgctgggag 1788241 cctttaatca atgggttaaa gggtcgcaat tagaaaattg gcgaaaccgc catgtggatg 1788301 aaatcgggaa aaaattaatg acagaaacgg cagtattgct tcatgaacgg atgcaatcga 1788361 tgtatcagcc gtcgcatgaa acagacaaca taaaaataaa agtttgaata ttatgaaaat 1788421 atacctataa aaatcattaa aataatccct tgaaggagag agcgcattat ggataaacag 1788481 agaatctttg aagtattaat caccaatatt tgcgaggtgc ttcctgaatt agacggacac 1788541 agatttgagc ctgaagatca gttagttgag ctaggagctg actctgtaga cagagctgaa 1788601 attatcacga tggtgctaga ggatttatcg ttaaaaatcc ctcgcattga gctatccggg 1788661 gtgaaaaaca tcggtgaatt agctgaggtg ctttatgaca aagtgcaatc tgcctgaggt 1788721 ggtggtgacc ggtgtaggcg ttacggcctc tatcggtcaa gggaaagagg actttgcttc 1788781 ctcgctgctg tccggcagac atgcctttga tgtcatgaag cgttcaggca gacaaaaaga 1788841 cagccggttt atcggagccg aaattgcgtc attgtcttat cctgaccgac tctctaaaaa 1788901 aatgttgcga aaagcatcat tctccagccg cgctgcattg gtaactctca cagaggcttg 1788961 ggaggaggct gaattggacg atgcagattc ctcacgtatc ggactggttg ttggcggatc 1789021 aaattttcaa cagagagaaa actttgaagt ttatgaaagg tatcaagacc gctccggttt 1789081 tatttctccg gcgtatggtc tgtctttcat ggacagcgat ctttgcggga tatgtacaga 1789141 tcagtttggc atcacgggat tagcatatac ggtgggagga gcttcggcca gcggccagtt 1789201 agcagtcatt catgcgattc agcaagtcct gtcaggcgaa gttgatactt gcatagcact 1789261 tggtgcttta atggatcttt cttatatgga atgcgaggcg ctaagggctt taggcgctat 1789321 ggggacggac aaatatgctg atgaacctga aaatgcgtgc cgtcccttcg atcaaaacag 1789381 agacgggttt atctatggag aatcgtgcgg tgcattggta atagaacgaa aggagacggc 1789441 tttacgaaga ggtctaaaac cttatgcagc attgtctggc tggtcaatca aactggacgg 1789501 aaaccggaat cctgatcctt cattagaagg agagattcat gtcatccaga aggcactgga 1789561 gcgtgccagg cttttaccag aagatattga ttatattaat cctcatggaa caggctcttt 1789621 tattggagat gaaatagaat taaaggcgct ccgtgcatgc cggctttccc atgcttatat 1789681 caatgcaaca aaatcgataa ccggacacgg gcttagtgcg gcgggcatcg tagagattat 1789741 ttctgttttg ctgcaaatga aaaaatctgc cctgcatccg agcaggaatt tggatcatcc 1789801 aatcgatgat tcctttcatt gggtaaatga gaaatcgatt tcataccgca tcaaaaatgc 1789861 gctgagctta agcatggggt ttggcggaat gaacaccgcg gtttgtatac aaaacattga 1789921 gaaatgtgga ggcgaatcat aaatggtttc agccggaata gaagcgatga atgtctttgg 1789981 cggaacggca taccttgatg tcatggagct ggccaaatac agacacttag atactgcgag 1790041 atttgaaaat ttattaatga aagaaaaagc ggtagcactg ccttatgaag atcccgtgac 1790101 cttcggagtc aatgcagcta agccgattat tgatgcttta tctgaagcag agaaggaccg 1790161 gattgaattg ctgatcactt gctctgaatc cgggatcgac tttgggaaat cgttaagtac 1790221 atatatccat gaatatttag gtctcaaccg caactgccgt ttgtttgagg ttaaacaggc 1790281 gtgttattca gggacagcgg gatttcagat ggcggtgaat tttatattat cccagacttc 1790341 tccgggtgcc aaagcactgg ttatcgccag tgatatttca cgttttttaa tcgctgaggg 1790401 cggagacgct ttaagcgaag attggtctta tgcggaaccg agcgccggag cgggagcggt 1790461 ggccgtttta gttggcgaaa atcccgaggt gtttcaaata gatcccggag caaatggtta 1790521 ttacggctat gaagtgatgg acacgtgccg ccccattccc gacagtgaag cgggagattc 1790581 tgatctgtct ttaatgtcat atttggattg ctgcgaacag acttttctgg aatatcaaaa 1790641 gcgtgtaccg ggtgccaatt atcaggacac gtttcaatat cttgcttacc atacgccctt 1790701 tggcgggatg gtgaaaggtg cgcaccggac aatgatgcgt aaggtagcga aggtgaaaac 1790761 atccgggatt gagacggatt ttttaactcg ggtaaaacca ggtttaaact actgtcaacg 1790821 ggttggaaat attatggggg cagccttgtt tctggcattg gccagcacga tagaccaagg 1790881 gagatttgat acgcctaaac gaattggctg tttttcctac ggatccggct gctgttctga 1790941 attttacagc ggaattacaa ctccgcaagg ccaggagcgt cagcgaacat ttggtattga 1791001 gaagcatttg gatcgccggt atcagctctc catggaagag tatgagctat tgtttaaggg 1791061 gagcgggatg gtgcggtttg ggacgcgcaa tgtaaagctg gactttgaga tgataccggg 1791121 catcatgcag tccactcaag agaagccgcg cttgttttta gaagaaattt ctgagtttca 1791181 tcggaagtac aggtggatct cgtgacctat caaacgataa aggtccgctt tcaagcatcg 1791241 gtttgctata ttacctttca ccgtcctgaa gcgaataata cgattaatga cacgctgata 1791301 gaagaatgct tgcaagtgtt aaaccaatgt gaaacatcaa cggtgacggt tgtcgtttta 1791361 gaggggcttc ccgaggtgtt ttgtttcgga gcggattttc aagaaatcta tcaggaaatg 1791421 aaaaggggca gaaaacaggc aagctcccaa gagcctctct atgatttgtg gatgaaattg 1791481 cagaccggcc cttatgtcac gatttcgcat gtcaggggaa aagtgaatgc cggcggtctt 1791541 ggatttgtat ctgccacaga tattgccatt gctgatcaga cggcgtcatt cagtctctct 1791601 gagctgctat tcggcctgta ccctgcttgt gttttaccgt ttctgatccg ccgtatcggc 1791661 cggcagaaag cgcattatat gacgcttatg acaaagccga tttccgttca ggaagccagt 1791721 gaatgggggt taatagatgc ttttgatgct gaaagtgacg tgctgctgag aaagcattta 1791781 ttgcgtttgc ggaggctgaa taaaaaagga atcgcacatt ataaacagtt tatgagctca 1791841 cttgatcatc aagtcagtcg tgcgaaagcc accgctttaa ctgcaaatca agacatgttt 1791901 tctgatcctc aaaaccaaat gggaatcatc aggtatgttg aaacaggaca attcccatgg 1791961 gaggatcagt aaccgtttaa aaatgacaat cagaaccgtt aggaggacat catgacgcat 1792021 tctgttgtag agcttatcga aattgaatcc gccattattc aggtaaagat gcaagatcgc 1792081 actcataaaa acgcgttttc acaagaactt acagacgatt taattcaagc gtttgaatac 1792141 atacggcaga atcccaaata caaagcggtc attttgacag gatatgataa ttattttgct 1792201 tcaggaggaa cgcaagaagg actgcttcga attcaacagg gattgaccaa gttcactgat 1792261 gacaatcttt attctctggc gctggattgc gagattccag ttattgcggc aatgcagggc 1792321 catggaattg gaggcggctt tgtcatgggg ctctttgctg acattgtcat tctgagcaga 1792381 gaaagcgtgt atacggctaa ttttatgaaa tacggattta cgcctggaat gggcgctacc 1792441 tttatcgttc ctaaaaaact gggtttcagc ctggcccagg aaatattatt gaatgcgggc 1792501 agctaccgcg gagctgatct tgaaaaaaga ggggttcctt ttaaggtgct gccccgtgca 1792561 gaagtgttag attatgcagt ggagctggcg caagaactgg cggaaaagcc gagaaactca 1792621 ctggttacac tgaaagatca tttggttgcc ccgcttcgcg atcagctgcc gcgcgtcatt 1792681 gaacaggaat tgatgatgca tgagaaaaca tttcatcatg aagaagtcaa aagtagaatc 1792741 aaaggtttat atggtaatta actgaaaata tatataaatt ttgcaggtga aatggaggca 1792801 gcgtgatgag aaataatgat aatatccgca tattaactaa tccttctgtc agtcatgggg 1792861 agcctttaca tatatctgaa aagcagccgg caacaatacc tgaagtttta tacagaacgg 1792921 cgacggagct tggggataca aagggaatca tttatttgca gccggatgga actgaagttt 1792981 accaatcata cagacgatta tgggatgatg gattgcgcat tgcgaagggg cttcgccaat 1793041 caggcctgaa agcaaaacaa agcgtgattt tgcagcttgg tgacaattca cagcttctcc 1793101 ctgcgttctg ggggtgtgtg ttaacagggg ttgttccggc tccattagcc gttccgccaa 1793161 cgtatgctga atcgagcagc ggcactcaaa agctgaaaga cgcatggacg cttcttgata 1793221 agccagcggt gattacggac cgggggatgc atcaggaaat gctcgattgg gcaaaagaac 1793281 aagggcttga agggttcagg gcaattattg tagaggatct gctcagcgct gaagcggaca 1793341 cagattggca tcaatccagt cctgaagact tagcgctttt attgctgact tcaggcagta 1793401 cgggaacgcc caaagcagtt atgcttaatc atcgtaacat tatgagcatg gtgaaaggga 1793461 ttattcaaat gcaaggcttc accagagagg atattacgtt taactggatg ccgtttgacc 1793521 atgtcggagg gatcggaatg ctgcatttgc gggatgttta tcttggctgt caggaaatta 1793581 acgtctcaag cgaaacgatc ttaatggagc cgttgaaatg gctggattgg attgatcatt 1793641 accgagcttc tgttacgtgg gcgccgaatt ttgcgtttgg tctggttact gattttgcag 1793701 aagaaataaa agataagaaa tgggatctgt cttcaatgcg atacatgctc aatggcggtg 1793761 aagcaatggt agccaaggta gggcgtagaa tacttgagct tttagaacca catggactgc 1793821 ctgctgacgc catccgacct gcctggggaa tgtccgaaac ttcatcgggc gttatttttt 1793881 ctcatgaatt tacccgggct ggaacaagtg atgatgatca ttttgttgaa ataggctctc 1793941 caatccccgg cttctctatg agaattgtga atgaccataa tgaattggtt gaagagggtg 1794001 agatcggccg ttttcaagtc tcgggtcttt ctgttactag cggttattac cagcggcctg 1794061 atttgaatga gagtgtgttt acagaagacg gctggtttga aaccggagat cttggctttt 1794121 tgcgaaacgg gcgcttaacc ataacaggcc gtacgaaaga tgcaattatc attaacggca 1794181 ttaattatta cagtcatgca attgagtctg cagttgaaga attacctgaa attgaaactt 1794241 cttatactgc tgcttgcgct gtccgtctgg gccagaattc aacagatcag ctggctatct 1794301 tctttgttac ttccgcaaaa ttaaatgatg agcagatgtc tcagcttctt agaaacatac 1794361 aatcccatgt ctcacaggtg atcggagtca ccccggaata tttgctgcct gtacaaaaag 1794421 aagagattcc aaaaacggct atcggaaaga tccagcgcac ccagctaaaa acttcatttg 1794481 aaaatggaga gttcgaccac ttgctacata aacccaatcg gatgaacgat gcagtccagg 1794541 atgaggggat acagcaagca gaccaggtga aaagagtaag ggaagaaata cagaagcatc 1794601 tgctcacctg tttgactgag gagctgcacg tttcccacga ttgggtggag ccaaatgcaa 1794661 atatccaaag tcttggtgtg aattctatca agatgatgaa gctcattcga tcgatcgaga 1794721 aaaactatca tatcaaacta acagctagag agatacatca atatcctaca attgaacgct 1794781 tagccagcta tctatcagaa catgaagacc tcagcagctt gtctgctgac aaaaagggca 1794841 cggacacata taaaaccgaa ccggaaagga gtcaggcaac ttttcagcct ctctctgagg 1794901 ttcaaaaagg attatggaca ttgcaaaaaa tgtcacccga aaaaagtgca tatcacgtac 1794961 ctctctgttt taaattttcg tcagggcttc accatgaaac attccagcag gctttcggcc 1795021 ttgtattgaa tcagcaccca atcttaaagc acgtcatcca agagaaagac ggagtgccat 1795081 ttcttaaaaa tgagccagca ctttcaattg aaatcaagac agaaaatatc tcaagtttga 1795141 aagagtctga tattcctgct tttcttagaa agaaagtaaa ggaaccgtat gtaaaggaaa 1795201 acagcccgtt agtgcgtgtc atgagctttt ccagatctga acaagagcat tttttattag 1795261 ttgtcattca ccatttgatt tttgacggag tttcgtctgt cacatttata cgcagtctgt 1795321 ttgataccta tcagcttctt ttaaaaggac agcagccgga aaaagctgtt tctcctgcca 1795381 tttatcatga ttttgcggca tgggagaaaa acatgcttgc cggcaaagac ggtgtgaagc 1795441 accgtacata ttggcagaaa cagctatcgg gaactttgcc gaatcttcag ctgcctaatg 1795501 tcagcgcaag ttcagtcgat tctcagttta gagaggatac atacaccagg cggttgtcca 1795561 gcggcttcat gaatcaggtc agaacgtttg cgaaagagca ttctgtaaat gtcacgacgg 1795621 tattcttaag ctgctatatg atgctgcttg gccgttacac aggccaaaaa gaacagatcg 1795681 tcggcatgcc ggccatggtg aggccggaag aaagatttga tgatgccatt ggacattttc 1795741 tcaatatgct cccgattcgg agtgagctga acccggcaga cactttttct agctttatat 1795801 caaaattgca attaacgata ttggatgggc ttgatcatgc agcatatcct tttccaaaaa 1795861 tggtgaggga tctgaatatt cctcgcagtc aagcaggttc accggtattt caaaccgctt 1795921 ttttctatca gaattttctt caatccggaa gctatcaaag cttgctgagc cgctatgctg 1795981 acttcttttc tgtcgatttc gttgagtata ttcaccaaga gggcgaatac gaattagtat 1796041 ttgaactgtg ggaaacagaa gaaaaaatgg agctgaacat caagtacaat actgggctgt 1796101 ttgatgcggc ttctatatcc gccatgttcg accattttgt ttatgtaaca gagcaggcga 1796161 tgttgaatcc ttctcagcct ttaaaagagt attctttatt acctgaggca gagaagcaga 1796221 tgattctcaa aacatggaac gccacaggaa aaacgtatcc atatataact tttcatgagt 1796281 tgtttgagca gcaggcgaaa aagacgcctg atagagcggc tgtcagctat gaaggtcaaa 1796341 cattgacgta tcgggagctt gatgagaaaa gcacacagct ggccatttat ttgcaggcgc 1796401 atggagtggg tcctgaccgt ctggcgggga tctatgtgga tcgatcgctg gacatgctag 1796461 tgggtttatt agcgatcctc aaggctgggg gagcgtatgt gccgctagac ccgtcctatc 1796521 cggctgaacg attagaatac atgcttgagg acagtgaagt tttcattaca ctgacgacat 1796581 cggaattagt aaatacgttg agttggaacg gtgtcacaac agccctttta gatcaagatt 1796641 gggatgaaat tgctcaaaca gcctctgatc gaaaagtgct tacacgcact gtcacgccag 1796701 agaacttggc atatgtcatt tatacatccg gcagcacagg aaagccaaaa ggtgtcatga 1796761 taccacataa agctttgaca aactttctcg tttcgatggg ggaaacacca ggtcttacgg 1796821 cagaggataa aatgcttgct gtcacaacct actgttttga tattgcagct ctggaattat 1796881 ttttgccttt aataaagggc gcacactgct atatttgtca aacggagcat acaaaagacg 1796941 ttgaaaaact gaaacgggac atccgcgcga tcaaaccgac agtgatgcag gcaacccccg 1797001 ctacgtggaa gatgctcttt tattcaggct gggaaaatga agagagcgtg aaaattttat 1797061 gcggtggcga agcattgcct gagacattaa aacgatattt cttagatacg ggcagcgaag 1797121 cctggaatat gttcgggcca accgaaacaa ctatctggtc agcggttcag cgcattaacg 1797181 ttgaatgctc tcatgccacg ataggaaggc caatcgccaa tacacaaatc tatattacgg 1797241 attctcagct cgcgccagtg ccggcaggtg ttccgggtga gctgtgcatt gcaggagacg 1797301 gtgtggcgaa gggctactac aaaaaggaag aattaacgga ttcgagattc attgacaacc 1797361 cttttgagcc tgggtctaag ctttatagaa cgggagacat ggcccgttgg cttacgggag 1797421 ggcgaattga atatataggc cgcatcgata atcaagtaaa aatccgcgga ttccgtattg 1797481 aacttggtga tattgaaagc aggcttagtg agcatcccgg cattctggaa tgcgttgtgg 1797541 tcgcagatat ggataaccta gctgcctatt atacagctaa acatgcaaat gcttctctca 1797601 cagcgagaga gctgcgtcat tttgtgaaaa acgctttgcc tgcctatatg gtgccttctt 1797661 attttattca gcttgatcat atgccgttaa ctccgaacgg aaagatagat agaaacagcc 1797721 ttaagaatat cgatttatca ggggagcagc taaagcaaag gcagacctct cctaagaaca 1797781 ttcaggatac tgtttttacc atttggcagg aagtgctgaa aacgagtgac attgaatggg 1797841 atgacggatt tttcgatgtg ggcggggatt cgcttctcgc ggtcactgtg gctgatcgta 1797901 tcaaacatga actatcctgt gagttttctg tcacagacct gtttgagtat tcaacgatta 1797961 aaaatatcag ccagtacatc actgaacagc gaatgggcga tgcaagtgac catataccga 1798021 cagacccggc agctcatata gaagatcagt ctaccgagat gagtgatctc ccggactatt 1798081 atgacgatag tgtggcgatt attggcatat cgtgtgaatt tccaggggca aaaaatcatg 1798141 atgaattttg ggagaacctc agagacggca aggaaagcat tgcgtttttc aataaagaag 1798201 agcttcagcg ctttggcatt tcaaaggaga tagcggagaa tgccgactat gtccctgcta 1798261 aagcttcaat tgatgggaaa gacagatttg atccaagctt ctttcaaatc tctcctaaag 1798321 acgctgaatt tatggaccct cagcttcgga tgctgctgac tcattcatgg aaagcaatag 1798381 aagatgccgg ttatgctgcg aggcagattc cgcaaaccag tgtttttatg tcggcaagca 1798441 ataattctta tcgcgcgctg ctgccgtcag atacaacaga gagcctggag acgccggacg 1798501 gctatgtttc gtgggtgctt gcacagagcg ggacgattcc gacaatgatt tctcataagc 1798561 tcgggctgag agggccaagc tattttgtcc atgccaactg ctcatcctct ctgattggat 1798621 tgcattctgc ctataagagc ctcctgtcgg gtgaatctga ttatgcttta gttggcggtg 1798681 caacgctgca taccgagtca aatatcggat atgtgcatca gcctgggctg aacttttcga 1798741 gtgatggaca tattaaagct tttgacgctt cagctgacgg aatgataggc ggtgagggcg 1798801 ttgctgttgt attgctgaaa aaagcagctg atgcagtaaa ggacggggat catatctatg 1798861 ccttgctgag aggcattggt gtaaataacg acggcgctga caaagtcggc ttttatgctc 1798921 caagcgttaa aggccaggct gacgtggtcc aacaggtcat gaatcaaacg aaggtacagc 1798981 ctgaatccat ctgctatgta gaagcacacg ggaccggaac gaagctgggg gacccgatcg 1799041 agctggcggc tttaacaaac gtttacaggc aatatacaaa taaaacgcaa ttttgcggca 1799101 ttgggtcggt gaaaaccaat atcggacatt tagatacagc cgccggtctt gcgggctgca 1799161 ttaaggttgt gatgagtctt tatcatcaag agcttgcacc gagtgtcaat tataaggagc 1799221 cgaatccaaa tacagactta gccagctctc ctttttacgt cgtcgatcaa aagaaaacgt 1799281 taagccgtga gatcaaaacg cacagggctg cacttagctc gttcgggctt ggcgggacaa 1799341 atacccatgc catttttgaa caattcaaaa gggattcaga taagggaaag atagacggaa 1799401 cctgcatcgt cccgatctcg gcgaaaaata aagagaggct gcaagagtat gcagaagaca 1799461 ttctggccta tttagaaaga agagggtttg agaacagcca gctgcctgat tttgcgtata 1799521 cccttcaggt ggggcgcgaa gcgatggagc atcgcgttgt ctttattgcc gatcatgtaa 1799581 atgagttaaa acagaggctc acagatttta tcaatggaaa tacagcgatt gaaggctgtt 1799641 ttcaaggaag taagcacaat gccagagagg tttcatggct gacggaggat gaggacagcg 1799701 ctgaactcat acgtaagtgg atggccaaag gaaaagtaaa caagcttgca gaaatgtgga 1799761 gcaagggagc gcatatagat tggatgcagc tttacaaggg agagcgccca aacagaatga 1799821 gtctgccgac ttatccattt gcaaaggaac gatactggcc gtcgcaggat gaccgcaaac 1799881 cggtggcgca gatatccgga aatcagacag ggatcggctc tattcatcca ttgcttcatc 1799941 agaatacatc tgatttttct gaacagaaat tcagttcggt tttcactggt gacgaatttt 1800001 tcctgagaga ccatgtggta agaggaaagc ctgtgcttcc tggtgttgcg taccttgaaa 1800061 tggcgtacgc ggctataaac caggcggcag gaagtgaaat tggccaagat gtcagaatca 1800121 gattgaatca tacagtctgg gttcagcctg ttgtggttga cagacattca gctcaagtgg 1800181 atatcagtct ctttcctgaa gaagatggaa aaatcacctt tgacatttac agtacacagg 1800241 aagacgggga cgaccctgtt attcatagtc aaggcagtgc ggagctggca tctgccgccg 1800301 aaacgccagt cgcagatctc actgaaatgt cacgccgttg cggcaaagga aagatgtcgc 1800361 ctgatcaatt ttacgaagaa ggcagaagca gaggaatgtt ccatggtccg gcctttcaag 1800421 gaattaagaa tgtgaatata ggaaacagag aggttttggc gcagctgcag cttccagaaa 1800481 tcgtttctgg aacgaatgaa cagtttgtgc tgcacccaag tatcatggat tccgccttgc 1800541 agacagcaac aatatgcatc atgcaggaat tgacggatca aaagctgatt ttgccatttg 1800601 cgcttgagga gcttgaagtg atcaaagggt gttcttcttc tatgtgggct tatgcccgct 1800661 taagtgacag cgatcactcc ggaggggttg ttcagaaagc ggatatcgat gtcattgacg 1800721 agagtggaac cgtatgtgtc aggatcaaag gattttcaac gagagtatta gaaggggagg 1800781 ttcatacttc aaagccttca acacggcacg aacgcttaat gcttgaaccg gtgtgggaaa 1800841 aacagaatga agaacgagag gacgaagatc tttcgtacac ggagcatatc attgttctct 1800901 tcgaaactga acgaagtgtc acagacagca ttgcctccca catgaaagat gcccgtgtga 1800961 ttactctaaa cgaagctgta ggacatattg ctgaacgtta tcaatgttac atgcagaaca 1801021 tttttgaact cctgcaaagc aaggtccgta agctttctgc aggccgtatc atcattcaag 1801081 cgattgttcc gctggaaaaa gagaagcaat tgtttgccgg cgtttccggt ctgtttaaaa 1801141 cagcagaaat agagttcagc aaactgactg ctcaggtcat cgaaattgag aaacctgaag 1801201 agatgataga ccttcacctc aagctgaaag acgacagccg gagaccattt gacaaacaga 1801261 ttcgatatga ggctggatac cgttttgtga aaggctggag ggaaatggtg cttccttcag 1801321 ctgatacgct tcacatgccg tggagagacg agggtgttta tctaatcaca ggcggagcag 1801381 gaagcttagg ccttctgttt gcaaaggaaa ttgccaatcg aactggccgg tctactattg 1801441 tgctgacggg acgatctgtt ttaagtgagg ataaggaaaa cgagctggag gctcttcgaa 1801501 gcatcggagc ggaggttgtc tatcgagagg ctgatgtaag tgatcagcat gcggttcgtc 1801561 atcttttgga ggaaatcaaa gaaagatatg gcactctcaa tggaattatt cacggtgcag 1801621 gcagcagtaa agatcgcttc atcattcata aaacgaatga agagtttcaa gaagtgttgc 1801681 agccaaaagt gagcgggttg ttacatgtag acgaatgcag caaggatttc ccattggact 1801741 ttttcatttt cttctcttct gtttcgggat gtttaggaaa cgctggacaa gccgattatg 1801801 cggcagccaa ttcgtttatg gatgcatttg ctgaataccg ccgttctctt gcggcatcaa 1801861 aaaagagatt cggctccacc atttccttca attggccgtt atgggaagaa ggcggtatgc 1801921 aagtcggcgc tgaagatgaa aagagaatgc tgaaaacgac gggaatggtc ccgatgccga 1801981 cagatagtgg cttgaaagca ttttatcaag ggatagtatc tgataagccg caagtttttg 1802041 tgatggaagg acagcttcag aaaatgaagc aaaaactgct ttccgcagga tcgaaagcca 1802101 agcggaacga tcagagaaag gcggatcagg atcaaggaca aactagaaaa ttggaagcag 1802161 ccttaatcca aatggttggc gcaattttga aagtaaacac tgacgatatc gatgtcaaca 1802221 cagagctgag tgagtacgga ttcgactcag ttacattcac tgtctttaca aacaagatca 1802281 acgaaaaatt tcaattggag ctaacaccga ccatattctt tgaatatggc agcgtccaaa 1802341 gcctggctga atatgtagtt gctgcgtatc agggcgaatg gaatcaagat gctactgcta 1802401 aaggcaaaga tgaaagaaca aacttagtgc acagtttaag cagcctggag gcatcattaa 1802461 gcaacatggt cagtgcaatt ttaaaagtaa atagtgaaga tattgatgtc aatacagagc 1802521 tgagtgaata cggatttgat tcagttacat ttacggtctt tacaaacaag atcaacgaag 1802581 aatttcagtt ggagctaacg ccgaccattt tctttgaata tggaagcctc cacagcctgg 1802641 ctgagtattt gaccgttgaa catggtgaca ccctggttca ggagcgagaa aaaccagagg 1802701 ggcaggaaga gttacagaca aaatcttctg aagcgccgaa aatcacatca cgtagaaagc 1802761 gccgctttac acagcctatt attgcaaaag cagaaagaaa caaaaagcag gctgccgatt 1802821 ttgagccggt tgcaattgtc ggcatcagcg gccggttccc tggcgctatg gatatagacg 1802881 aattttggaa aaacctagaa gaaggaaaag acagcatcac agaagttcca aaagatcgat 1802941 gggattggcg ggagcattat ggaaacccag acactgacgt caataaaacc gacatcaaat 1803001 ggggtgggtt tattgatggt gtcgcagagt ttgatccgtt gttttttggt atttcgccgc 1803061 gagaagctga ttatgtagac cctcagcagc gcttgttaat gacatacgtg tggaaggcat 1803121 tggaagatgc gggttgctcg ccgcaaagcc tttcgggtac agggaccggt atctttatcg 1803181 gtacgggaaa caccggttat aaagatctat tccatagagc gaatcttcca attgaaggcc 1803241 atgctgctac aggtcatatg attccttcgg taggcccgaa tagaatgagt tattttttaa 1803301 atattcatgg tccgagcgag ccagtagaga cggcttgttc cagttctctt gtagccattc 1803361 accgtgctgt gactgcgatg caaaacggtg attgtgagat ggcgatcgct ggaggcgtga 1803421 atacgatctt aaccgaggag gcgcatatta gctacagcaa ggcggggatg ctcagcacag 1803481 acggcaggtg taaaaccttc tccgccgatg cgaatggcta tgtcagaggc gaaggggtcg 1803541 gaatggtcat gttgaaaaag ctggaagatg ccgagcgcga cggaaatcat atttacggcg 1803601 ttattcgggg cacggcggaa aatcacggcg gaagagccaa taccctgaca tcgcctaatc 1803661 cgaaagcaca agctgatttg ttggtgcgtg catatcgcca agcagacata gatccaagca 1803721 ctgtcacata tatcgaagca catggaacag ggacggaatt gggcgatccg attgaaataa 1803781 atgggctgaa agccgcgttt aaggaactat ccaatatgag aggcgagagc cagccggatg 1803841 ttccggatca ccgttgcggc atcggctcag ttaaaagcaa tatcggtcat ttagagctag 1803901 cagccggtat ttccggtttg atcaaggtgc ttttgcaaat gaagcataaa acgttagtga 1803961 aaagcctgca ttgcgagacg cttaatcctt atcttcagct gactgacagt ccgttttaca 1804021 tcgttcagga aaaacaggaa tggaagtctg tcacagatcg tgacggaaac gagcttccgc 1804081 gccgtgccgg aatcagttcg tttgggattg gcggagtaaa cgcgcatatt gtgattgaag 1804141 aatatatgcc aaaagccaat tcagaacaca cggctacaga acagccaaac gtaattgtgc 1804201 tgtcggctaa aaataaaagc aggctgatag atcgtgcttc gcaattgctt gaggtgattc 1804261 gcaataaaaa atatactgat caggatttgc accgcatcgc ttacaccctg caggtcgggc 1804321 gcgaagaaat ggatgagcgt ctggcgtgtg ttgcggggac aatgcaggag cttgaagaga 1804381 aactgcaggc gtttgttgac ggtaaggaag aaacagacga atttttccgg ggacagtctc 1804441 atcgaaataa agagacccag actattttta cagcagatga agatatggcg ttggcacttg 1804501 atgcttggat cagaaaaaga aaatacgcca aacttgctga tttatgggtc aaaggggtct 1804561 caatccagtg gaacacatta tacggagaga ccaaaccgcg cctgatcagc ctcccttcat 1804621 atccgtttgc gaaggatcac tattgggtgc cggcaaagga acattcagaa agagacaaaa 1804681 aagaactggt taatgcgatt gaagatcgcg ccgcatgctt tttgacgaaa caatggagtt 1804741 tgagtccaat tggatcagca gtgccgggga caagaactgt tgccatcctg tgctgtcaag 1804801 agacagcaga tttagcagca gaagtgtctt cgtattttcc gaatcatctc ttaatagatg 1804861 tgagccggat agaaaatgat cagtcagaca ttgattggaa agagtttgac ggcctagtgg 1804921 atgtcatcgg atgcggttgg gatgatgagg gccggctgga ttggattgaa tgggtgcaaa 1804981 gactggttga attcgggcat aaagaggggc tcaggctgct ttgtgtgacg aaggggctcg 1805041 aatcgtttca aaacacatct gtccggatgg ctggcgcctc acgggctggg ttgtatcgaa 1805101 tgctccaatg cgagtacagc catcttatat caaggcatat ggatgctgag gaggttactg 1805161 atcatcgccg tctcgcgaag ttgatcgctg atgagtttta ttccgattct tatgatgcgg 1805221 aggtttgcta cagggatggt ttacggtatc aagcttttct aaaagctcat ccggaaacag 1805281 gtaaggccac ggaacagagc gcggtcttcc cgaaagatca tgtacttctc attacaggcg 1805341 gcacacgagg catcggacta ttatgcgccc gtcattttgc agagtgctat ggagtgaaaa 1805401 aactggtgct gaccggacga gaacagcttc ctccgcgaga ggagtgggct cgttttaaga 1805461 catcaaacac atcattggca gagaaaatcc aggcagtgcg ggagctggaa gcgaagggtg 1805521 tacaggtgga gatgctgtcg ctgacgttat ctgatgatgc tcaggttgag caaacgctgc 1805581 aacatatcaa gcgaacatta ggaccgattg gcggtgtcat tcattgtgca ggtctgacgg 1805641 atatggatac gctggcattt atccgaaaaa cttcggatga tatccagcgg gtgctggaac 1805701 ctaaggtgtc aggtcttaca acgttatatc gccatgtgtg taacgagcct ttacagtttt 1805761 ttgtcttatt ttcttctgtt tcagccatta ttccggagct ttcggcggga caagctgact 1805821 atgcgatggc caatagctat atggattatt ttgcagaagc acatcagaaa catgcgccga 1805881 tcatcagtgt tcagtggccg aactggaaag aaaccggtat gggtgaagtg acaaatcaag 1805941 cgtatcggga cagcggcttg ttgagcatta cgaattcaga aggcttacgt tttctagatc 1806001 aaattgtatc gaaaaagttc ggaccggttg ttctccctgc aatggcgaat caaacaaact 1806061 gggagccgga actgctgatg aagaggagga aaccgcatga gggcggtttg caggaagctg 1806121 ctttacagag cccgccagcc agagacattg aagaggccga tgaagtttcc aaatgtgatg 1806181 gattattatc tgaaacacag tcctggctta ttgatctgtt taccgaagag ctgagaatag 1806241 atcgtgaaga cttcgagatt gacgggttgt ttcaggatta tggcgtggat tcgatcattt 1806301 tggcacaggt gctccagcgt ataaaccgca aattagaggc agcgctcgat ccatcgattc 1806361 tatatgaata cccgacaatt caaaggttcg cagattggct gatcggttct tattccgaaa 1806421 ggctgtccgc tttattcgga ggcaggatat cggatgcatc agcacctttg gagaacaaaa 1806481 tagaggcgga ggcatctgtt cctgggaagg atcgagctct tacacctcag attcaggcgc 1806541 cagcgatttt gtcaccggac tctcatgcag aaggtattgc cgttgtcgga ctctcttgcc 1806601 gattccctgg ggcagagaca ttggagtcat attggtcgtt actatccgag gggcgttcgt 1806661 caatcggccc gattccggca gagcgttggg gctgtaagac gccatattat gccggcgtga 1806721 ttgatggcgt cagctatttt gatcctgatt tctttttgct tcacgaagaa gacgtaaggg 1806781 cgatggatcc gcaagcactg ctcgtgttgg aagagtgtct gaagctcttg tatcacgccg 1806841 gttatacacc tgaggaaata aagggcaagc ccgtcggtgt ttatatcgga ggcagaagcc 1806901 agcacaaacc tgatgaagac agccttgatc atgccaagaa tccgatcgtg acagtcggcc 1806961 aaaattattt agccgctaat ctttcacaat tttttgatgt ccgcggtcca agtgttgtag 1807021 ttgacactgc atgctcgtca gctttggtcg gcatgaatat ggccattcag gcgctgcgtg 1807081 gcggagatat tcaatccgcc atagtcggcg gtgtcagctt gctgagctca gatgcgtctc 1807141 acaggctgtt tgaccggcgc ggcattttaa gcaagcattc atccttccat gtgtttgatg 1807201 agcgtgctga cggagttgtg ttaggtgaag gcgtcggaat ggtcatgcta aaaaccgtaa 1807261 aacaggcact ggaagacgga gatatcatat atgctgtcgt caaagcggcc tcggtcaata 1807321 acgacggaag aacggcggga cctgcaacac ctaatcttga ggcacaaaag gaagtcatga 1807381 aagatgcgct tttcaaaagc ggaaaaaaac cagaggacat cagctacctt gaggcaaacg 1807441 ggtcaggttc aatcgtaacc gatctccttg agctaaaagc gatccaatca gtgtaccgtt 1807501 ctgggcactc atcgcctctt tctcttggct caatcaagcc gaacatcggg catccgctat 1807561 gtgctgaagg gatcgccagc ttcattaagg ttgtgctgat gctgaaagag cgccgctttg 1807621 tcccattttt atcaggtgaa aaagagatgg cgcatttcga tcaacagaaa gcgaacatca 1807681 cgttcagccg agccctggaa aaatggacag attcgcagcc tactgcggct attaactgct 1807741 ttgccgatgg ggggacgaat gcccatgtca tcgtagaggc gtgggaaaaa gatgaaaaac 1807801 acgccatcaa gcgcagtcca atatcgcctc ctcaattaaa gaaacgaatg ctttcgccag 1807861 gcgagccaaa gctggaagcg gagacttcaa aaatgactgc ggcaaacata tgggatactt 1807921 atgaggtgga ggtctaacgt gaaaaagata acgaaacaac tcacattatc gttaaaaaat 1807981 ccgtttattt atcaccatgt ggtttacgga caaaatgtcc tgccgggatt ggcttatatc 1808041 gatataatct accagatatt cagagaacac ggtttctcct gctcagagct tcagctgcgg 1808101 aatttatcca tctatcagcc attgacggcg gaacaggatg cagtaattgt tttgaatatc 1808161 caatgcgcgg agaaaaaaga aggacagtgg caaatcacag ccaagggaat tgaaaaacgt 1808221 gatgggaaag aagcttcaga agaaaagctc tatatgaagg ctgacatgca cgcagactcc 1808281 ccagccatat ttgaagaaac actggatctc agtcaaatca aagcatctgc acagaacgtt 1808341 gttcagcttg atgatgtata tgaacaatgc agacgtcagg aattggtgca cagcgaatat 1808401 atgaaagcaa aaggctgcat ctatgaagag gaagacggcg tccttcttga gctttctctc 1808461 ggttcggagg ccatgcttca cgcagaaggc tttatgtttc acccgactct catagacggg 1808521 agcggggtgg gtgccaatca tttgctcaca tctttgctta aaggagaaca gaggctgtat 1808581 ttgcctctgt tctatgaatc cttttccgct tctgcacttt tgcaaacgga ttgcatgaca 1808641 agaattaagc gctcctccgt ccggcgggaa aaagagctga tttatgtaac acttgaattt 1808701 tttaatgcgt cgggagaaaa agtggctgag ttgaaaaact ttacaagcaa attggtgcga 1808761 gaagcggagc tgattagcgg aaaacatcaa gatgcacagg agacacagat gacaagagcg 1808821 gacactgctg agcgtgataa acctgctgac atggtatctt ctcccgttaa ttcctatagt 1808881 gaggctgaac agttcgtaag ccaattaatc gcagagaaaa tcaataagcc ggtagaacaa 1808941 gttgaaaaac aggtcggtta ttaccaaatg ggactgaatt catcgggctt gcttgaggtg 1809001 gtagaaacga tcagtgataa gatcggtgag agcctttcgc cgactcttct gtttgagcat 1809061 accaccatag cggaactgtc agcgtttctt gccgaggaat atgctgagca ttttagtgcc 1809121 gctggttctc ttggccagaa tgaaagagca cgcgtttccg acagcataaa cgaccataag 1809181 actgttgaag gctctcgtcc tgcacctatt gaggcagcag gcgatattgc gattatcggc 1809241 ttggcgggca ggtatccgaa ggcagccaat attcatgaat tttggaacaa tctgaaagag 1809301 ggtaaggact gcgttagtga gattcctgag tcgcgctggg attggcagcg acttgaagga 1809361 atcacatctc cttcgggtaa ggacatttcc aaatggggag gatttattga tgatcccgac 1809421 tgcttcgatc cccaattttt cagaatcacg ccaagagaag cggagacaat ggaccctcaa 1809481 gagcggctgt ttttagaaac atgctgggaa acgattgaag atgcgggcta tacgccaaag 1809541 acgttggcca agcctaaagg acgaaataaa aggcagcatg taggagtttt tgcaggcgtc 1809601 atgcacaagg attatacatt agtcggagct gaagaagcat cagcagaaaa tgtgtttcct 1809661 ctttcgctca actatgcgca aatcgccaac cgtgtttctt acttttgtaa tttccacggt 1809721 ccgagtatgg ctgtcgatac ggtatgttca tcctctttga ccgcagtgca cttggcgttg 1809781 gaaagcatac gtcacggtga gtgcgatgtt gcgttagcag gcggagtgaa cctgtctttg 1809841 cacccgaata aatatatgac atacggggtc tgggatatgt tttccactga cggacactgc 1809901 cgtacgtttg gaaaggatgg agacggttat gtgcctgcag agggtatagg cgcggtttta 1809961 ttaaagcctt tgcgccaggc agaggaagac ggagatcgca tttatgcagt tattaaagga 1810021 agtgctgtga atcatgtggg cactgtaagc ggcatttcag tgccgagccc tgtttcccaa 1810081 gctgatctga ttgagacatg cttggagaaa acgggaatcg atccgcggac gatcagttat 1810141 gtggaagccc atggaaccgg cacgtcctta ggagatccga tcgaaataca gggattagtg 1810201 aaagcgttcc gccaatatac gcaggatcgg cagttctgtt caatcggttc tgtaaagtca 1810261 aacattgggc acgccgaatc cgccgcgggg atcagcggtt taagcaaggt tgctcttcag 1810321 cttcaccatc aaaaacttgt gccttctttg cattcggaag aactgaatcc gtacgttgat 1810381 tttgaaaagt ctccatttta tgtacagcat gaaacagaaa cgtggaagca gcctgttatc 1810441 aaggagaatg gggaagacgt cccttatccg cgacgggcgg ggatcagttc ttttggcgca 1810501 acaggttcaa acgcacatat tatccttgag gaacatattc ctcaagcagc ggagcaggac 1810561 gtttctttgt cctcagattc tgacatatcc gcagttattc cgctttctgc ccgtaatcaa 1810621 gaacgtctcc gtgtatatgc aaaacgtctc ttggattttc ttcatgatgg gattcagatt 1810681 agagatttgg cgtatacatt gcaggtaggc cgtgaaccga tggaagaacg ggtttctttc 1810741 ttagcatccg gaattcaaga attgagcgac caattgaagg cttttataga aggacgaaaa 1810801 gccattcagc attgctggaa gggccgcgtg tcaagaggaa gcgaaccatc gcgtcccgcc 1810861 gaatcggtac ataaattgct ggagcaaaga aaactcgatc agattgcgga gcagtgggcg 1810921 aacggatctg gtgttgactg gaagctgctt tacgagggaa gcaaaccaaa gcggatcagc 1810981 ctgccgactt acccatttga gagggtgcgt tattgggtgc cgaaagcgga gaaaaagact 1811041 gatcgttcaa aacaggagcg gcacatcctg catcctcttc tgcatcaaaa tgtgtccgac 1811101 atatcgggtg tccgcttccg ttcagcgttt acaggacgtg aatttttctt gaaggatcat 1811161 gtcataaagg gcgaacacgt tttacctggc gcagctttat tggagatggt tcgggcagct 1811221 gtggaaaggg cagctgcgga tcagttcccg acaggattcc ggctccggaa tatcgtctgg 1811281 gtccggccgt tcgccgtcac ggaacagcag aaagatatag atgtacgtct atatcctgag 1811341 gaaaatggtg agattacatt tgaaatctgc cgggaccctg aaagcgcaga ggagtcgccg 1811401 attgtatatg ggcaagggag tgcagtgctt tgtgaggctg gtgaaaatcc ggttatcaac 1811461 attgaagaat tgaaggcaag ctataatggc cggacgctgt caccttttga ttgctacgag 1811521 gcttatacag aaatgggtat tcattatggt gacagccaca gagcgatcga cagcctatat 1811581 gccggcgaaa acggagttct agtgaaattg acgatgcctc ctgtaatctc tgatacagaa 1811641 gaccattata ttctgcatcc gagcatgata gattcggcat ttcaagcatc tatcggtttg 1811701 aggctgggag gagctacgag tttagaagac agaaaggcaa tgctgccttt tgccatacag 1811761 gatgtccgaa tcttcaaagg ctgcgaggca tctatgtggg cgcggatcac atatagcgag 1811821 ggcagtacag ctggggatcg tatgcagaag cttgatatcg atttatgcaa tgaagagggc 1811881 caggtttgcg tgcgattgac gagctattct gcaagagtgt tagaaacaga tcaagaaggt 1811941 ccttctgaag cgaatgacac gctattgttc gaacatattt gggaagaacg tgctgcagag 1812001 aggcaagagc tcatagagta cgacacgtat aaagtcgttg tctgtgatgt tggagaacaa 1812061 atggaaagcc tccaaaatca tcttgactgt acagttctgc agcatgatac agagacaatt 1812121 gatgaacggt ttgaaggtta tgccatacag ttatttgaag aaatcaaaca gctaatgcac 1812181 tcaaaaacag gaggacatac attcattcaa gtggcggtgc ctgcgttgga cgagcctcag 1812241 ctattaagcg gcttaactgg attgctcaaa acggctgaac tggaaaatcc aaaactgaca 1812301 ggacagttga tcgaaataga aaccgggatg tcagctggtg agctattcga aatattggag 1812361 gaaaacagac gctatccgcg tgacacgcat atccgccact ggcaagggaa gcgatttgta 1812421 agcaagtgga aagaagtgtc tggtgagcac ctaagtgctg acatgccatg gaaggataaa 1812481 ggcgtgtatc tgatcacagg cggtgcgggc ggtctgggat tcatctttgc aactgaaatc 1812541 gcaaaccaaa cgaatgatgc ggttgtgatc ctgacaggac gctctccgct tgatgaaagg 1812601 aagaagaaga agcttaaagc cttacagaaa cttggcatcc aagcgattta cagacaagct 1812661 gatctggctg acaaacaaac ggttgatgcc ttattaaaag aaacccaaaa cgtttacgga 1812721 gacttagatg gcatcattca tagcgccggt ttaataaaag ataatttcat tatgaagaaa 1812781 aagaaagaag aggttcaaac cgttcttgct ccaaaggtag caggactgat tcaccttgac 1812841 gaagcaacga aagatattcc gctcgatttc tttatccttt tttcctcagg tgccggagca 1812901 gtaggaagcg cgggacaggc tgattacgca atggccaatg catttatgaa tgcattcagc 1812961 gaatatcgaa atggccaagc agagctgcat aagcgttacg gaaaaactct ttcagtgtgc 1813021 tggccgctgt ggaaagacgg gggcatgcaa attgatgcgg aaactgcaag gatgctgaaa 1813081 agagaaacag gcatggtggc catggaaaca gatcgtggga ttcaggcgct atatcatggc 1813141 tggacgtcag gaaagccgca agtgttagtt gcttccggtg ttactgatcg gattcgtgca 1813201 tttttacatg aaacgggaca tggcaaaggc caatctcaca atatcaaaaa aagcagtctc 1813261 aatcaggagg cagaaaaagc agacatgatc ggggaaattg atgaagagat actaagagaa 1813321 aaagcggaga actattttaa acaggtgctt tcttcggtga ttaagctgcc agctggccag 1813381 attgatgctg aagctcctct cgaggattac gggatcgatt ctatcatgat catgcatgta 1813441 acgggtcaat tagaaaaagt attcggatct ttgtccaaga cgctgttctt tgaataccag 1813501 gatattcggt cattaacccg gtattttatt gattcccgca gagaaaaact gctggacatc 1813561 ttgggatttg aaacgggaaa accttctgtt gaaagaaaat cagaacctga aaaacaagaa 1813621 atcccagtta tcccaagaaa gtctggattt cttcctttgc aagataaaga gcagaagcag 1813681 gtaagagaga aggaaacgga agaaattgcg atcatcggta tctcaggtcg ctatccgcag 1813741 gcagacaaca ttgatgaatt atgggaaaaa ctgagggacg ggcgagactg tattacggaa 1813801 attcctgcag accgctggga tcacagtctt tattatgacg aagataaaga caagcctgga 1813861 aaaacctaca gcaagtgggg cggcttcatg aaggatgtag acaagtttga cccgcagttt 1813921 ttccatattt cgccgcgtga ggcaaaatta atggacccgc aagagcgttt atttttgcag 1813981 tgcgtgtatg aaacgatgga agacgcaggc tatacaagag agcacctcgg ccgtaagcgt 1814041 gatgctgagc ttggcggaag cgtcggtgtt tacgtcggtg tcatgtacga agaatatcag 1814101 ctgtacgggg cacaagagca ggtgcgggga aggtctctgg ctttaacggg aaatccatca 1814161 tccatcgcga accgggtatc ttattatttt gattttcacg gaccgagtat tgctttagac 1814221 accatgtgtt cttcttcttt aacggctatc cacttggcct gccaaagcct gcagcgcgga 1814281 gaatgtgagg cggcattcgc gggcggcgtg aatgtgtcaa tccatccaaa taaatatttg 1814341 atgctcgggc agaacaaatt tatgtccagc aaaggccgat gtgaaagctt cggacagggc 1814401 ggagacggct atgtgccggg ggaaggcgtt ggagcagtgc ttttgaagcc attgtctaaa 1814461 gcagttgaag atggtgatca catttatgga atcattaagg ggacagccat caaccacggg 1814521 ggaaaaacaa acgggtactc agtgcccaat ccgaatgccc aagcagatgt catcaaaaag 1814581 gcgtttgtgg aagcgaaggt tgatccgcgg acagtcagtt acatcgaagc ccacggcacg 1814641 ggaacctctc tcggtgatcc tattgaaatc acagggctgt ccaaagtgtt tacgcaagaa 1814701 accgatgaca aacaattttg tgcaataggg tcagccaaat caaatatcgg gcactgtgag 1814761 agtgcggcag gtattgcagg agtaacgaag gtattgctcc aaatgaaata caggcagctt 1814821 gcgccttccc tgcattcaaa cgtgctgaac ccgaatattg atttccttaa ctcgccgttt 1814881 aaagtacagc aagagctaga agagtggaag aggccgatca tcagtgtcaa tggcaaagac 1814941 atcgaattac cgagaatcgc aggagtctct tcatttggtg ccgggggtgt gaacgcccat 1815001 attttaatag aagagtatgc tccggaacct gtggaggaac gtttaccagc gaggaaacag 1815061 ccggctgtca ttgtgctctc agcaaaaaat gaggaaagac ttcagaaacg cgcggagcga 1815121 ttgctgcatg ccattcgtga acaaacatat gttgaagcag atttacaccg aattgcctat 1815181 acgctgcaag tcggccggga agcgatgaaa gaacggctgg cgttcgttgc ggaaacgatg 1815241 caagagcttg aagaaaagct gtatgaatgt atctccggaa cagaaaatcg tgaatatgtc 1815301 tatcgcggac aagtaaagag caacaaagaa gccattgctg cttttgctgc tgatgaggat 1815361 atgtcaaaaa caattgaggc atggctgcaa aaaggaaaat atgcgaaggt tttagacctg 1815421 tgggtaagag gtttgcgaat cgactggagc acgctatatc aggatcaaaa accgcggcgc 1815481 atcagtttac ctgcctatcc tttcgcaaga gatcgctatt ggatagacgt aaatgcaaag 1815541 gctgaggaaa aaagaacgga ggagccattc gctccagtac agcccgttat tccgaagccg 1815601 tctgtagaca gagaagccag tggcaagcct gccaatatta cgttacagcc tttaatgacc 1815661 aatcaggatc gtttagagcg tgttccatca gatacagaaa cagagacgat cacggcggaa 1815721 gccttgtgcg atgaactgac agcgggctta gcggaagtgc tgtacatgga ccaaaacgag 1815781 attgatccag acgaagcatt catagatatc ggtatggact cgattaccgg gctcgaatgg 1815841 ataaaagcaa taaataaaca gtatggcaca tcactaaatg tcacaaaggt atatgattat 1815901 ccgacaacac gtgatttcgc tgtttactta gcacacgagt taagcacaca agctggggag 1815961 aaaaaacaaa cggagacgta cacgccgatc agacaaaaaa cagtggtacc tgctgctaaa 1816021 ccggctaata tatctctgca gccgttagaa catcatcagc cagtgcaaga ggaagctgaa 1816081 gaaacgattc aatatgcagc ggcagaaata tctgcatcaa gacaatatac tgtagcaatt 1816141 gaaacgctgc atgaaaactt gagggaaagc atagcagacg tgttatacat ggagccatac 1816201 gaggtggata ttgacgaagc gttcatagat atcggaatgg actcgattac cggactcgaa 1816261 tggataaaag cggtgaacaa gcaatacgga acgtctttta cggtaaccag agtatatgat 1816321 tatccaacga tacgtgattt tgccgaaatg ctaaagtccg agcttggaac tcatcttgat 1816381 agaaagatag agcatactga ctctttcgaa gcagcccagc aaaagccagc agcatcatct 1816441 catccaaagc cggcagaacg gccactacag cctgttcaac atccaataaa gaaagaacat 1816501 gagaagaaaa cggttcctgt tcttcaagac cgcccggagg atgcgatagc gattgtcggg 1816561 atgtcgggaa gatacccggg cgctcgtaat gtaagagagt actgggataa cctggttcat 1816621 gcgagaaatg ccattcggga cattccaaca tcacggtggg atgttgacaa atactatgat 1816681 cctgtcctca acaaaaaagg gaaagtctat tgcaaatcaa tggggatgct tgatgatatt 1816741 gaacattttg atccgttgtt ttttaatatt ccgccgtcag aagctgaact gatggacccg 1816801 cagcatcgaa tctttttgca ggaaggctat aaagcctttg aggacgctgg gtacaacgcc 1816861 cgaactttaa atgagaaaaa atgcggtgta tatctcggca ttatgagcaa tgaatacggg 1816921 gtcatgctga atcggcagtc aagagcaaat gccaccggaa acagctttgc gatcgcagcg 1816981 gcgcgtattc cgtattttct aaatttaaaa gggccagcga ttcctattga taccgcatgt 1817041 tcatcttcat tggtcggcac tcatttagcg cgccaggcac ttataaacaa agaaattgat 1817101 atggcgctgg tcggcggggt cagcttatac ctgacgccgg aatcttacat gagtatgtgt 1817161 gaggccggca tgctttcacc tgatggacaa tgtaaagcat ttgacaatgg cgcgaatggt 1817221 tttgtgcccg gcgagggtgc gggtgcgctg gtattgaaaa ggctgaaaga tgcggaagcg 1817281 gaccgtgacc atatttatgg catcatcatt ggctcgggta ttaatcagga cgggaaaaca 1817341 aacggaatca cggcaccgag tgcgaaaagc caaatggatc tggaaagaga catatatgaa 1817401 acatacggca tacatcctga gagtatcagt tatgtcgaga tgcacggcac aggaacaaaa 1817461 caaggcgatc caattgaatt agaagctctg tccaccgtat ttcaagaaaa aacagacaaa 1817521 aagcagtttt gcgcaatcgg ttccgtcaaa agcaatattg gccatacatc cgcggcggca 1817581 ggagtagccg gggttcaaaa agtgttattg tgcatgaatc ataaaacact tgtgccgaca 1817641 ttgaacttca cgacaccgaa tgagcatttt gaatttgagc attctccttt atacgtaaat 1817701 acggagctta agccttggga aacggctgat ggaaaaccgc ggagagcatg tgtgagctcc 1817761 ttcggatata gcggaacgaa tgcccatatt gtgatagagg aatatcagcc tgaaaagagg 1817821 aacgatcgat taacaaagca gcaccgctca gcattatttg tactctcagc gaaaaaagag 1817881 aagcaattga aggcctatgc ggaagcaatg aaagatttcg taacttccaa tgaagatatc 1817941 gatctggagg atatggcata cacacttcag acgggccggg aagcaatgga ttatcgcatg 1818001 gcgtttttgg cggattcgag agaaatgctg atcaaagctt tagatgatta tttggctgaa 1818061 atgccgaacg gcagcatatt tgctgctcac gtgaaaacga agaagagcga aatcaagctg 1818121 tttgaaacgg atcatgatgc caaagcattg ctgcaaacat ggatagagaa aaaaaggctg 1818181 gagaaagtag cagagctatg ggtgaaaggg ctgcagatag attggaacaa gctttatggg 1818241 gaatacacgc ctcgccgaat cagcctgcct gcttatccgt tcgcggaaga gtattactgg 1818301 ctgccaactc aagaaggcga acccgaaacc attgctacag caatgcctca attcgaactg 1818361 atgccaaagc gctgctttct gcgtaaacag tggcagcctt gtccgattga accggcagaa 1818421 atgacgaatc aaaccgtcgc cattttggca aatgaggaga caatggcatt agcggaagag 1818481 ctttcggcgt atttctcgac ataccgtata tttgacagcc aagagctgga tcgggtatct 1818541 gctgctgact atgaacacgt tgctggagca atcgatctga tcgggtgcgg aacgagccat 1818601 gagcattcta tgggctggat aaactggctc caaaagctga tcgagcaagg acgtgcaagc 1818661 aagcatcatt tgacggtctt gggtgtaaca aaggggctgg aggcctacgc aaatgagggt 1818721 gttcttttgt ctggtgcttc acgggccggt ttataccgca tgcttcaaag tgagtacagc 1818781 catcttactt caagacatgc agatatggaa tgcgaagcct ctcatgagga gctggccaga 1818841 ctgattgcag ttgaatatta tgccaagagc acagaatcag aagtctgtta tcgaaacgga 1818901 cagcgatatc gcgcatattt gacagagcag ccagcagaag ccgctctaag tcataagcaa 1818961 gtatcgtttt caacagacaa agtcctgctt attacaggcg ggacaagagg tctcggcttg 1819021 ctgtgtgcgc ggcattttgt gaaaacatac ggcgttaagc ggctggtcct tatcggccgt 1819081 gaagagcttc cgccgcgtga ccagtggaat tcggtaaaaa tttcctcgct tgccgagaaa 1819141 ataaaagccg ttcaagagct agaagacatg ggtgcgcaag ttcaggtgct gtctctggat 1819201 ctcacagaca gggttgctgt cgaacagagc ctgaagacaa tacacgaaac aatgggggcg 1819261 attggcggag tcatccattg tgccgggatg gtgaacaaac aaaacccggc ttttatcaga 1819321 aaatcactag aagagatcgg acaggtgctt gaaccgaaag tcgaaggtct gcaaacgttg 1819381 tttgacctgc ttcaagatga accattggcg tttttcacct tgttttcatc agtatcagcg 1819441 gccatccctg cactagcagc aggacaagct gattacgcga tggcaaatgc ttttatggat 1819501 tattttgcgg aggctcatca agataaatgt cccattgtaa gcattcagtg gcctaactgg 1819561 aaggagaccg gtttaggcga ggttcgaagc aaagctttag aacaaactgg attgatcagt 1819621 ttgacaaacg acgagggatt acagctgctt gaccagattc tatcagacag acagtatgct 1819681 gtcgtgctgc cggcagtacc agatacaaac gtttggaagc cggataagct gatgcagccg 1819741 tcattgcctg tcgaagctct ctcgcatcct gagacgaaag agcaaaccag cactcgcaac 1819801 ctgttccctg aaacagtcga ctggctcgta actctttttt cagatgaact gaaaatagct 1819861 gcagaagact ttgaaacgga tgaacctttc caagaatacg gaatcgactc gattatattg 1819921 gcccagctgg tacagcagat gaaccaacaa ttaaatggag atattgatcc gtcaatcttg 1819981 tttgaatacc cgacaataga atcctttgca cactggctca tttcgaaata tgacatatca 1820041 gctgttttac agccatctgt tcctgagaaa cagacacctc tcaagccgca atcagcaatg 1820101 aaacagaagc tggtgccaga acagcggccg caacagataa gccatgaaaa aacggcactt 1820161 cttgctgagg acatcgctat catcggtctt agttgcaggt tcccgggagc agaaacccta 1820221 gaggaatact gggatttaat acgtgatgga cggtctgcga ttgcgcctgt tccgcctgaa 1820281 cgattcggga actccagctc gaattacgcg ggcctcattg atgaaatgaa ccgatttgat 1820341 catgatttct tcatgatgtc cgaaagcgat gtcagagcga tggaccctca agctttggct 1820401 gtattggagg aaagcttgaa gctatggtat cacgcgggtt atacagagaa agaagtgaaa 1820461 ggcatgaggg ctggtgttta tataggaggc cgcagccagc acaagcctga tccggccagt 1820521 ctttcaaaag caaaaaatcc gatagtcgct ggtggacaaa actatttagc ggctaacatc 1820581 tcacaatttt ttgacttgaa gggaccgagt attgtcctgg ataccgcttg ttcctctgca 1820641 ctggtggggc tgaatatggc cattcaggct ctgcgaagcg gagatattga ggcagcggtt 1820701 gtaggcggcg tcagtttgct tgatgctgat gcgcatcgaa tgtttcatga gcgcggactt 1820761 ttatgtgaca aaccgtcatt ccatattttt gataagcggg cagacggtgt cattttagga 1820821 gaaggcgtgg gcatggttct cgtcaaaacc gtcaaccaag cggttgaaga cggagattcc 1820881 atatatgcag tcattaaagc cgctgcgatt aataatgacg gaagaacggc aggcccatca 1820941 tctccgaatc tcgaggcaca aaaggacgtc atgctgtcag cgcttgaaaa aagcggcaaa 1821001 aagactgaag agatcagcta tctcgaagcg aacggatcgg ggtcggcagt aacagattta 1821061 cttgaattaa aggcaatcca gtccatttac cgttctgaat caaaggctcc gttagggctg 1821121 ggatcggtga aacctaacat cggccatcca ttatgtgcag agggaattgc gagcctgatt 1821181 aaagtagctt taatgctgaa gcatagacaa ttggttccgt tcctgtcagg taatgaaaat 1821241 atgccgtatt ttgatataga aaaaacagat ttgtatttca gcagatcgca agccgagtgg 1821301 aaggagacaa cgccggctgc ggcaattaat tgttttgcag atggcggaac gaacgcccat 1821361 ctcattatag aaggttggag agactcggct gagcgtccaa ttagaagaaa acctctgcct 1821421 ttgccggaat taaataggca gcccgtttta atcaaaccat cagctcaaaa cgtgcagaaa 1821481 aaagtgcatt cagacacagg ggcttctaaa gatatgtttt ggaaaacttt caaataagag 1821541 aggagtggga aaatgataac tgaacaactg cacatttcat taaataatcc aatcatgtcc 1821601 aaccacaagg tatatggaca agcgttatta cccggccttg cttatataga tttaatctac 1821661 caagtattcc aggaacatgg ttatgcatac caagagcttg aattaaaaaa cctaaccatt 1821721 ttttaccctt tgatcgcaga tgagtcatat gacattgccc tgaccattca cgtgtctgaa 1821781 agaaaggaag ggacatggtc catcatcatc gacggacaaa aacagcatgg agaatcacta 1821841 tctgacaaga gacaatatgt gactgctgac atgcatcgta aagagcaaac cgcttttgcc 1821901 gaatcaatag accttaatca gtggaaaagt acagctgaca ggattctgaa tttagatgaa 1821961 atctatgaac aatgccgatc tcaagagtta gtgcataccg gcatgatgaa ggcggaagga 1822021 cagatttatg aagccaaaga gggggctgta attgatttag cagtcggaca ggaagcattg 1822081 cgtcattctg atgcttttct gtttcatccg acgcttattg acggcagcgg cataggttca 1822141 agctgcctga tctcagatca aacgatgtac ctgccattgt attatgaatc gttttctgct 1822201 tcagaacgat tgcaaaaagg atgtacagca cggatcctct cctcatctgt gcgccaaaag 1822261 aaagaactca cttatatgac gattgaatat tttaattcag caggacaaaa agtggccgag 1822321 ctgaaacaat ttgcaggcaa gtctgtacgg aatatgtcag cctttcattc tgcaaaagaa 1822381 attcaagaag aaagagctgc tgtctctcag aacatcagtc gggactatcc cgcatttgaa 1822441 atgtatttgc gtcagctgct tgctaagcag cttgaaaggc cggcagaaca aatggatatc 1822501 cacgctgggt actatgagct tggtctggat tcttcgtcat tgcttaccgt ggttcaggaa 1822561 attggagata aggttggggc ggatcttgct ccgacactgc tgtttgaatt tacaacaatt 1822621 gcagaactag ctgctcatct tgctgatcac tattcaattg gagaggcgga cgatgctgtc 1822681 cgccaatctc cttcaccaat tgatggtgtt acctcttcac cagagatcgg ggaggacata 1822741 gccattatcg gaatggcggg acgctatcct aaggcgaaaa atatacagga attttgggaa 1822801 cagcttaaag cgggtaccga ctgcatcaca gagattccaa actcacgctg ggaatggaaa 1822861 gaaagcgatg gactggattc acctgcaggc aagccgctct cgaaatgggg cggctttatc 1822921 gaggaggctg attgctttga tcctcaattt ttcagaatct ctccgcgtga agcggaaatg 1822981 atggaccctc aggaacgctt atttttagag acgtgctggg aagctattga agatgcgggt 1823041 tatacaccag agacaattgc ttcaccgcag ggagaaaata aaagacagca tgtcggtgtg 1823101 tttgccggcg ttatgcataa ggactattct cttataggag ctgaagctct atcagaacac 1823161 aatccatttc ctttatcgct gaattatgcg caaatcgcca acagggtctc ttactattgt 1823221 aatttccacg gcccaagcat ggcggtggac acggtctgct cttcctcatt aactgcggtt 1823281 catctggcaa tagagagcat ccggaatgga gaatgcgagg ccgcgcttgc cggaggcgtc 1823341 aatttgtcac tgcatccggc taaatatatc agctatggca gtgtagggat gcactcaagt 1823401 gacggctatt gccatacttt cggcaaaggc ggggatggct acgtatctgg agaaggtgtc 1823461 ggcacagtat tgctaaaacc gctgcgaaaa gctgaacagg acggtgaccg aatctatgct 1823521 gtcatcaaag gcagtgcgat aaatcatgta ggaaaagtaa gcggaattac agtaccgagc 1823581 ccggtagctc aagctgatgt aatcgaagca tgtctagaaa aaacaggaat tgatccgcgc 1823641 accatcagct atgttgaagc ccatggcact ggcacctcat tgggagatcc gattgaagta 1823701 caggggttag taaaagcttt cagccgcaat acgcaggaca agcaattctg ttcaatcggt 1823761 tctgtgaaat caaatattgg ccatgctgaa gctgcagccg gcattagcgg cttaacgaag 1823821 actgtcctgc agctgcatca taaaaccttg gtgccgtcat tacattcaga agagctgaat 1823881 ccttatttga agcttgatca aaccccattt tttgtccagc atgaaacaaa ggaatgggag 1823941 cagccatctt ttacagaaaa cggggtggac gtcacatatc cccgccgtgc cggtttaagt 1824001 tcgtttggcg cttcaggatc aaatgcgcat cttattttgg aagaatatat tccggcagag 1824061 agccattcag agacgatttt aacgaaaaat gaagaaatag tgataccttt gtctgcgaga 1824121 aacaaagatc gtctgcaggc ttacgctctt aaacttcttg attttcttag cgaggacgtc 1824181 aatcttttag cgttagctta taccatgcag gcaggacggg ttgaaatgga ggagcgtgcg 1824241 gccttcattg taaaagacat aaaagattta acggctaaac ttcgggcgtt tgccaatggc 1824301 gaagaagaga tcgagggctg ctggaccgga cgagccaagg agaatcagga ggcggctggg 1824361 ctagcatcgg taaatgcgct gaataacaat ttgataagag acagtgaaat gatggaaatg 1824421 gcgaaagcat gggttcaagg aaagcgggtc acctgggacg acctatacgg cgatcgcaag 1824481 ccgcttaaga tcagtgttcc gacctatccg tttgcaaggg agcgctactg gatctcggtt 1824541 cctgaaatga aaaccagcac tgtgaatcat atcttacatc cgctggtgca ccgcaataca 1824601 tcagacttta ctgagcagcg ctttagctct gtatttacag gcacggaatt tttcctgtca 1824661 gatcatgttg tacagggaca gaaaattttg ccgggcgttg cctatttaga aatggcaagg 1824721 gaagcagcgg aaaaagctgc aggcgatctg gacggcgaac aaagagtggt gtcgcttaaa 1824781 gacattgtgt gggtgcgtcc tatcacgata gaaagtgaac caaaagaaat acatattggc 1824841 ctttttcctg aggataacgg ggacatttcc tttgatattt atagcagctc tgaacataaa 1824901 gaagaagccc tgacgataca ctgccaaggt cgcgctgtca tttcagatga agcggagact 1824961 tccattttaa acctttcatc aatacagaca gaatgcagcc tggacacagt gacgtcagaa 1825021 caatgctatg cagcgtttcg aaagattggg cttgactatg gcgagggcta tcaagggatt 1825081 gaaaaagtct atgtcggcaa agatcaattg cttgcaaaaa tctcgttacc cgcttttcta 1825141 aaaaacgaca agcagcattt tgcgctccac ccgagtttga tggattccgc gttccatgcc 1825201 acagtcggtt ttatcgttag ctcagtcaat gccgctggac aagctcagac gctgtctctt 1825261 ccatttgcgt tacaggaggt tgatattttc agcccatgtc cagagaagat atggtcttat 1825321 attcgataca gttcagacag taaagcggag aacaaagtca gaaagtatga cattgattta 1825381 tgtgatgaga acggacgtgt ttgtgtgcga atgaagggtg cctcgatgcg ggcacttgat 1825441 ggagagcagc attcaaagcc gcaactatta actgattctc agctgaccgg gcatacggtg 1825501 atgatccccg tctgggaacc agtctctcta gaagcggagg ataatgcttc gtttgctggt 1825561 aaaagagctg ttttatgcgg agctgctgaa gctgatcgga ctttcataaa gcatcattat 1825621 ccgcaaattt cctttgtcga tatccgccct gcagatgaca ttgaggcaat agcggacaaa 1825681 ctgcaagcgt acggaagcat tgaccatgta ttgtggattg ccccgtcaca ccggggaagt 1825741 ataggtagtg atggacaaga agaagctgtt cttcacttat ttaagcttgt gaaagcatgc 1825801 ctgcaattag gctatggcga gaaacaactt gaatggtctc ttgtgaccgt ccaagcgcag 1825861 ccggttacgc aacatgaggc agtacaaccc gctcatgcaa gcattcatgg gcttgccggc 1825921 acaatggcaa aggaatatcc acactggaaa atccgtcttc tcgatcttga aaaaggctgc 1825981 acatggccgg taaatcacat gtttgcgctc ccagctgacc gccttggcca tgcttgggcc 1826041 tatcgtaatc agcaatggca tcagcagcaa ttgatcccat atcggtcctc actgtcaggc 1826101 gacacgctat atcggaaagg cggagtctat gtggtcatcg gaggagccgg gtatatcgga 1826161 gaggcgtgga gtgagtacat gatccgccgc taccaggcgc aaatcgtttg gattgggcga 1826221 agtcaactta atgctgccat ccagtcaaaa atagaccgac tttcggcgct tggccctgag 1826281 cctttctaca ttgcagccga tgcagccgat aagcattcac tgcagcaggc ttatgaacaa 1826341 gtgaaaaaac gtcatcctca tattcacggg attgttcact ctgcgatggt tttatttgag 1826401 caaagcctgg aaaaaatgaa gccggaagaa ttcaccgctg gactggcggc gaagatcgat 1826461 gtcagtattc ggatggccca agtgttccgc caggagaatg tagattttgt tttattcttc 1826521 tcttcgcttg tagcccatat caaaaatgtg aagcaaagcc attatgcctc tggctgtaca 1826581 tttgcagatg cttttgctca ccagctttct cagagctggg catgccctgt aaaagtcatg 1826641 aactggggat attgggggaa tagtgaagcg gctgaggatg aacattatgt acagctcatg 1826701 aatcaaatcg gcttaggttt aattgagccc gcggaggcta tgaaggcgct ggaagcactg 1826761 ctttctgggc cagtcagcca aacagctttc attcatacga caaagcctgt agcagtcgaa 1826821 ggcgtgaatc agaatgaatt catcactctt tatccagagc aaccttcagc agatgcagag 1826881 agcctgatgg agcgtctgcc gactacggga cgatttcaaa gagtgacaca tgaagagctt 1826941 gatgatcttc tttacaggct gttgttagga cagctgcaaa cagccgagct gtttgatggt 1827001 tatacattat cggttgaacg tcttcaacaa tataagactc gtgaatttta tggaaaatgg 1827061 attcggcaaa gcagcgaatt tctcttgcag catggctatc ttaagaaagt tggagattca 1827121 ttggtgagga aggaccaagc agaggatatc gagctgcttt ggctagaatg gaacgcgaaa 1827181 aaagaaaagt ggcttaaaga cagcgagaca aaggcgatgg ttgtattagc agaggccatg 1827241 ctgcaagcat taccggatat tttgacaggg aaagtccctg caacagatat catgttcccg 1827301 cattcctcga tggaactggt ggaaggcatt tataagcata accaagtggc agactatttt 1827361 aataaagtgc ttgccgatac attattagct tatctggatg aacgtctgaa gcacgaccct 1827421 gaggcatcga ttcgcattat ggaaataggc gcaggcacag gcggcacgag tgccggaatc 1827481 tttgaaaaac tgaaaccata tcaaaagcac atcaatgaat attgctatac agatctgtct 1827541 aaagcatttt tgctgcatgc agaaaaggaa tatggggcgg aaaatccgta cctgacatat 1827601 cagctttttg atgtggaaaa accgattgat cagcaggaat ttgaagcggg aggctatgat 1827661 gtcgtcattg ccgctaatgt ccttcacgca acaaaaaata tccgtcaaac actgcggcat 1827721 acaaaagcgg taatgaaaaa caacggaatg ctgctgctga atgaaatggc gggaaacagc 1827781 ctgttccctc acatcacctt tggtcttttg gaaggctggt ggctgtatga agatcctgca 1827841 gtgcggattc ccggctgtcc aggcttacat cctgacagct ggaaagcggc acttgaaagc 1827901 gaaggctttg aatctgtctt tttcccggcc gaggcggcac atgatctgag tcaccaaatc 1827961 gtcgcagcct caagcaacgg gctggttcga cgtatgatga aaaatgtgat cttgccggag 1828021 aaggttgttt cacaagcgtc taatcaggag ccagcctaca ttcataccat agattcagag 1828081 gaagctggac aatcgaaaca tgctctccta agagaaaaaa gcacagaata tatgaaaaaa 1828141 ctaatcgggg aaacgttgaa aattcctgca ggaaagattg agtcatctga acctcttgaa 1828201 aagtacggta ttgattctat cgttgttgtc cagctgacga atacattgcg taaagaattt 1828261 gaccatgtaa gcagcacttt atttttcgag taccagacca ttgacgcatt agtggagcat 1828321 ttcatcaaaa caaaaacaga agctctgatg aaattaacag gtcttgaccg tcaagttcaa 1828381 caacatacac cggccgaaag cagaacccaa tcttcacaga aacctgatca ggccgctaaa 1828441 agaacacggc gctttcgcaa gcttggcttc agcggggaga aagaaacacc gacaaacact 1828501 cttgcaagcc gtgacgttgc cgttatcggc atttctggac gctatcctca ggcggaaaca 1828561 gcagaagact tttggaacaa cctaaaagaa ggaagaaatt gtattgagga aattccgaaa 1828621 gatcgctggg attggaaagc ttattacgat aaagaaaaag gaaaagaagg atcaatttat 1828681 acgaaatggg gcggatttat caaggatatg gacaagtttg acccattatt ctttcagatt 1828741 tctccgcttg aggcagaaag aatggaccct caggagcgat tatttctgca aaccgcttat 1828801 gcaagtattg aagacgcggg atacacgcct gactcgctct gttcaagcag aaaaatcggc 1828861 gtctttgccg gagtcatgaa caaaaattat ccgactggct acggctattg gtctatcgcc 1828921 aacagaatat cctatttact gaatttccaa ggcccgagtc ttgcagtcga tacagcctgc 1828981 tcatcctccc tgacagcgat tcatttagcg ctggaaagca tctatagcgg atcgagtgat 1829041 tgtgccattg ccggcggtgt caatttagtt gtcgacccgg ttcactatca gaatttatct 1829101 gtcatgaata tgctctctgc tagtgataca tgtaaatcat tcggcgatga tgcagatgga 1829161 tttgtcgacg gtgaaggcgt aggcgccatt gtgttaaagc cgctgcagca agcaatagcg 1829221 gacggtgacc atatttacgg tgtgataaag gcaagtgcca ttaatagcgg aggaaaaaca 1829281 aatggataca cggttccaaa tcctcatgca caggcacagg tgattaaaga agcaattgag 1829341 cgcgccgaca ttcctgcccg aaccatcagt tatttagagg cgcatggaac aggcactgca 1829401 ttaggagatc cgattgagat agcggggtta acaaaagcat tcgagaaaga tacgcaggag 1829461 aaacagtttt gtgcgatcgg ctccagcaaa tcaaatatcg gccattgtga aagtgcagcc 1829521 ggaattgcag ggctgacaaa aatacttttt cagtttaaat atggccaaat tgcgccatca 1829581 ttgcatgctc agcggttgaa tccgaacatc gagttcagcc atacgccatt tgtcgttcag 1829641 cagcaacttg gtgaatggaa acgcccggtg attggcgggc aagaggtgcc taggcgcgct 1829701 ggcttgagca gttttggcgc cggagggtcc aatgcccata tcatcctgga agaatatatt 1829761 ccaagaacgg gggcgcaaac gccgaaagac catcctccag cgctgattgt gctgtcggcc 1829821 aaaaacatgg aacgtttgca agaaaaagcg gaacagctgc ttacagccat caaacaaaaa 1829881 aggtactgcg aaacagacct gatcaggatc gcctatacct tgcaaacagg ccgtgaagca 1829941 atggaggaac ggctggcctt tatagcggaa tcactagagg atcttgagag aaagctgaac 1830001 gattttatcg aaaacaaagc agacagcctg tatctggatc gcatcgatga taacaaaaaa 1830061 gcgttagcag tcttatcagc ggatgaggat acggaaaaaa tcatagaagc atggatgagc 1830121 aaagggaaat acacgaaact gctggatctt tgggtgaaag gcttgtcttt cgactggggc 1830181 atgctgtacg gcacccaaac gcctgtccgg atcagtcttc cggcatatcc atttgcaaaa 1830241 gaacgttact gggcaccagg cgcggcaaag gccccggtgt ctatagaaca ggatcatgat 1830301 cagcaaacag aagaaccttt caaggttatg acgtttcaag aagtgtggaa agaagagccg 1830361 gcgactctca catcgaaacg tatcaaaacg ctcatctgtt ttctgactga aagagaaaag 1830421 caaaacgcat ttgcttcagc cctgaaaaac gttgatcaag acaccaaggt catttttata 1830481 tcacagggcg aagtgtacag caaacagtct gaatatagct accagattgt gcggcaagaa 1830541 cccgttactt ttgaaaaggc cttccagagc attaaagaag aacttggaga gccagatgca 1830601 atcctctata tgtggcctat ggaagacaag cgctgtataa aggaccattc ctgtattgtt 1830661 tacctattac aaggtatgtc cgcagcaaag cttcatcctt cacggctgct gctggcagga 1830721 tgttttgaag atagtcttga ccgaagttat ctggaatcat ggattggctt cgaacgttca 1830781 ctcgggcttg tccttccgca cacaaaagtg actggaatct ttcagcccgc ggaacaagga 1830841 tcgatggatg attggacacg taaagtctgg gcagaattac aggcttcaac tgaacaaacg 1830901 gttttgtatc agaatctgaa acgatatgta aatcacattg aacagacaac gatacaaccg 1830961 gacaacagca aattgaagtc tggcggtact tacctgatta caggcggtgt aggagggctt 1831021 ggttatttat ttgccaagca tttggccaaa aactatgccg caaacctgat tttgacaggg 1831081 aggtcgcctt ttaatgatga gaagcaaaag caaataaaag aattaaagga tctaggcggc 1831141 gaagcgatgt atgcagaagc agatgtgtct gatcctatcg caatgggaga ctgcgtaaaa 1831201 agagggaaag accgattcgg tgccatcaac ggtgttattc atgcagccgg aatcgagagc 1831261 gactctgcta tttttgacaa aaagatcgaa agcttccagc gcatcattga accgaaaatc 1831321 aacggcacga tagcgcttga tgaatggctt aaaaatgaag accttgattt tatgtgttat 1831381 ttttcttctt cttctgcggt tttaggggat tttggatgtt gtgattatgc gattggcaat 1831441 aggtttcaga tggcttacgc acaatacaga aatgagctgc ataacggtaa aacgtttgtc 1831501 atcaactggc ctgtgtggaa ggatggcgga atgaagatcg gtgatgagga aacaacggat 1831561 atgtacctga aatcaagcgg ccaacgcttc ctagaagccg aggaaggtat ccgtatgttt 1831621 gagcacatcc tagctcagca ggatgctcag catctcgtga tagccggtca gcccagccgt 1831681 gtcagcagat ttttaggaat gactgaacca gctattccag aaccggccac tcaagcccct 1831741 ctagcacaag aaaacaagga tgaggtaaaa acactaagca ttgaaaagcg tttagaacac 1831801 gacttgaaag agcatattca cacattgctt aagatttcaa aggacaagct gaatttgaac 1831861 aaaaattggg ccgacttcgg atttgattcg atctatttgg ctaaattctc gaacgtgtta 1831921 tcaaagcatt tcaacatcga agtgacaccg gctttatttt tcggctattc aactttacaa 1831981 gaattgatca gctttttctt aaccgatcat aaagagctga ttgaagcatt ttaccgggat 1832041 gatgcatcag aggcgcaaaa gccccctgaa gcttatgcag taattcctgt agctttagaa 1832101 ccagaagcca gtaaaaaaag cattcggcag gttcacgatg agcctattgc cattatcggc 1832161 atgagcggca ggttccctca agctgattcg gtccatgagc tgtgggataa tctgaaaaac 1832221 ggtaaatcgt gtatctctga cattccgggc gaacgccggg actgggggag agctaacaga 1832281 gatccagaaa aagcagtgcc aaggtggggt gcatttttga aggacataga ccggtttgat 1832341 ccgctgtttt ttcaaatatc gcctaaagaa gccgaaagca tggacccgcg tcagcgcatt 1832401 tttctagagg aagcatggca cacgtttgaa gacgccggct atatgggaga tcggataaaa 1832461 ggaaaatcct gcggtgttta tgtaggtgtg gaagaagggg aatatgcgca tctaaccgga 1832521 gatacggatt acattaacgg aacacaaaac gccacattgt ctgcgagaat cgcatacgca 1832581 ttggatttaa aagggcctaa tatggctttg acagcagcat gttcatctgg actggtggcg 1832641 attcaccagg catgttcagc tctgcgtcag ggggattgtg aaatggcttt agcgggcggc 1832701 gtcagcttga atatttctca catgtctttt gaggcgctga caagggccga aatgctgtct 1832761 ccgaacggac aatgcaaagt gtttgaccag gatgccaatg gtcttgtgcc aggtgaagcg 1832821 gtggctgctg ttctcttgaa accattatca aaggcaattg aagataaaga tcatatttat 1832881 ggctgcatca aggccagcgg cgtgaattac gatggcaaaa ccaacggcat tactgcgcca 1832941 aatcctttta gccaggcaga attgatcgaa aacatttatg aaaaaaatga aatcaatccg 1833001 ctcgatattc aatatgtgat ggcgcacagt accggctcga atcttggtga tccgcttgag 1833061 gtccaagcgt taacgagcgt gttcagcaaa tatacgaagc agaagcaatt ctgtatgatc 1833121 agctcaatta aacctttaat cggacataca tttgcagcgt caggaacggt tgctttaatc 1833181 agtatgctga tggctatgaa aaaccagatc attccggcca ctcatcactg tgaatcggaa 1833241 aacccgtata ttccgtttaa agaaagccca tttgtgcttt gcaaagaaaa ccgttcgtgg 1833301 atcaagaaaa atcagaagcc gaggatggga acgatcagca cgactggaat cagcggcacc 1833361 aatgcacatg cagtcattga agaatacatt ccggatgatc agccgtccac acagcggcat 1833421 caagggtcac cgcagatctt tgtgatttca gcccaaaatg acgatcggct tcaggatgct 1833481 gcctgccgca tgattgcgta tctggagcag aatcataacc tttctttacc tgatgtggca 1833541 tatacgcttc aggttgggag aaaagccatg gaagcaaggc tcgcgatcgt tgcaaacaat 1833601 caggagcaat tggtgcgaaa attgaaggaa tatgtggaag caatgaagaa tggtggggta 1833661 tcaggccaac agagatccct ttatacagga tatacagaag ggattttaga agaacaagat 1833721 gaagcagttc tgcaagctct cgcaaaagaa agaaatttgg aaaacatcgc ggaatgctgg 1833781 gtgaaaggat atcagattcc ttgggaactc cttcatgatg gcgatgacgt tcggatggtt 1833841 tctttacctg gttatccatt tgcaagggaa cggtattgga tttcgtcagg cactcagcaa 1833901 tcagaggccg ttaaacagca ttcacaagat atgaaaacag agattgacga gccgaatggc 1833961 aaaacccata ttcaaaagat cattgttcaa tttttagcac gagaattggg catatctgag 1834021 gatcgaatca atttcaaaag aaacttcctg gattatggga tggattcaat tcttggccga 1834081 aaattgatgc ggcatatcga aaaaaccacg cagctgaaga tggccggccg ggaaatcctt 1834141 gaatgtcaga cagtccaagc tctatctgac catttggcct taaaagcgga aaaacaaaat 1834201 catagcgcag cagcacatca cataaagggc acgtatacag acgagcaaat cattggattg 1834261 atgcaagagg tggcgctagg gaaattggat tttaagagtg tgcaaaacat catagaaggg 1834321 agtaaatcgt atgaatcata aagaaattct cgatgccttc agatcaggag aattaaccat 1834381 ttctgaggtg gaagaacatc ttaaaggcat gaagcggcag ttgaaaagcc cgctttcaga 1834441 agggcaaaaa gggctgtgga tgcttcaaaa aatgtctcct gggatgagtg catataacat 1834501 tcctttatgc tttcgcttca gcaaaccaat acatgcagag acgttcaaga aagcccttct 1834561 gtttgtacag agacaatatc cggtcttagc cagtgtgatt caagaagaaa atggcattcc 1834621 atttcaatcg gttcagttat caaaggatct ttattttgtg gaagaggata tatcagcaat 1834681 gaaatcagca gatattatgc cttttctaaa agaaaaagca aaagaacctt tccagttgga 1834741 agctggtccg ttatggcgca cacacctttt tcatcggtta gaagaatgca ttgttcttat 1834801 aacaattcac catatcatat ttgatggtgt gtcgatgctg acattgatat cggcgctatt 1834861 cgaagcgtat caacaattgc tgaatgggat tgaacccttg cagcagccat caacagctga 1834921 ttattacgat tttgtcgatt gggaaaatcg aatgctgact ggcagagaag gggaagagca 1834981 tctcgcttac tggaaagaac agttgtctgg gagtctgcca gttcttgatt tgcctgctga 1835041 ccgtccgcgg tcttcagcac gaaaatttaa ggggcaagct tataaaagct tgctccctca 1835101 tcacctgaga aatcaaatta aatcgtttgc ccgcaccaat catgtgaatg aatcggttgt 1835161 gtttctctcc atttacaaag tgctgctgca tcattataca aaacaaaagg atatcattgt 1835221 tggcgttccg acaatgggtc ggcaagaaga cagatttgaa accctaatcg gttattttat 1835281 caatatgatg gctgttcgga gcaagaatat cggatctcag ccattaacag catttattcg 1835341 ggaactgcag ctgacagtgg ctgtcggcct ggatcatgcg gcgtttccgt tccctgcatt 1835401 ggtaagagag ctgaatgtag accgctcggc cgcggattct ccggtttttc aaacagcttt 1835461 tctgtaccaa aacttttttc aggcaacagg cttgcaaaaa gtgcttgaac cgtatcaaac 1835521 gcttggcatc gaatatattg aagacattcg gcaagagggt gaatttgagc tggcgctcga 1835581 aatatatgag caagaaaatg aaacagtgct tcatcttctg tacaaccctg atttgtacga 1835641 actgtcctcc attgaaagca tgatggagaa ctatatgaag ctcgcgcagc acatgatgga 1835701 ggacccgtct ttgccgcttg aagcctactc tttgcaatta aatcaagaac aaactagttt 1835761 gctggaacaa tggaatgcga cagggacaaa catcgcaaat gacaagtgta tacatgaggt 1835821 gtttgaggaa aaagcgaaac aaacccccga tgcggttgct gtgatgtttg aagacagatc 1835881 acttacatat aaagaagtag atgaaaaaag cacatctgtg gcagtctacc ttcaacatca 1835941 gggtgttaga cctgaacagc ccgttggcat ttgtgcagag cgttcgtttg atatgatcat 1836001 cggaatttta ggaatactga aagctggcgg agcgtatgtg ccgttagatc caagttttcc 1836061 gcaagaacga ttaaagtaca tgctcaaaga cagtcaggca tccattgtcc tcacccaacc 1836121 taacgttcat gataggatca gcggattaac tggcagccat gtaaaagcga tcaatatcga 1836181 gttagcttgc cgaaacggtt atacagacca gcaaagcagc ggtttaaagc gggaagtaaa 1836241 accggaacac ctcgcttata ttatttatac atcgggaagc accggagagc ctaaaggggt 1836301 tatggtagag catcggagca ttatgaatac cctgaatttt cttgaatctc actatcctgt 1836361 aacggctgag gatgcatatt tattgaagac gaactatgtg tttgatgtat cgatctcaga 1836421 attattcgga tggtttattg gagatggccg tctagtgatt cttccgccta atggggagaa 1836481 atcaccgcag ctttgcatgg attatattga aacatataaa gtgactcaca ttaattttgt 1836541 gccggccatg ctgcatgttt ttttagaaat ggcgaaagac aacaagcgat tcacagagga 1836601 cggtccgctg aagtatatga tggttgcagg tgaagccttc cctaaagtat tagtgaaaaa 1836661 ggcggtatcg ctctttacaa actgccgtgt tgaaaatata tacggaccga cggaagcctc 1836721 catttacgct gcgtatttcg gatgcggaaa aggagatatc gcaagtcacc atacaccgat 1836781 tggaaagcct gtttccaaca cgaaaattta tattgtggac cagcatttga agcctgtccc 1836841 gatcggaaag ccaggtgagc tttgcatcgc tggagccggc ttagcaagag gctactttaa 1836901 aaagccgggg cttacggctg aaaaatttat tgataatccc tttgaatcag ggacgaagct 1836961 atataaatcg ggtgattcag caaggtggct tcctgacggc aacatagaat acttgggacg 1837021 gattgacagc caagtcaaaa tacgcggttt tcgcgtcgag ctgggcgcaa tagaaacaaa 1837081 gctgggtgaa tttccgggca ttttagatca ggcggtagtg gtgaagcagc ttgagggcca 1837141 tcaacagctc gctgcttatt atacagagga aagcggacat gcctctgcca atccaaaaga 1837201 tttgcgcctt catctaaaat cgagtctgcc cgaatatatg ataccttcac actttatccg 1837261 cttagatgag cttccattat cgcccagcgg aaaagtgaac cgtaaagaat tagaaaaacg 1837321 cgagatcgtg ttcaacagaa ggaaaccaaa tcacttgcaa ttaacggaaa tagaggatca 1837381 ggtgctgcgc atttgggagg aaacgctcaa ggtcagcgga tttgggccgg aagacggatt 1837441 tttcgatgcg ggcggcgatt cgcttctggc tgtagctgtg gctgaacgaa tcaaaaaaga 1837501 attcgattgt gagtttcatg ttactgagct gtttgagtat tccacgatcc gtgcaatcag 1837561 tgaatacatt ttggagatga aaaactcaga tctagccggg acacaaaatg aagatgatca 1837621 tgatgacaaa aaagatggaa aatacccgaa acagaagatt cccccttatt ttgacgacag 1837681 tgttgcgatt gtggggatat cttgccagtt cccgggtgcg aaaaatcatc atgacttctg 1837741 gaaccacatc aaagaaggca aagaaagcat acgattcttt tctgaagaag agcttcgcgc 1837801 aaatggagtt cccgaagaat tgatacagca tcctgactat gtgcctgtgc aatctgtgat 1837861 cgaagggaaa gacttattcg atcccggttt ctttcaaatc tcgccaaaag atgctgagta 1837921 tatggaccct cagcttcgcc tcttattgct gcactcctgg aaagcgattg aagatgcagg 1837981 atatgtggct aaggagattc cggcaacaag tgtatatatg tctgcaagca gcaattcata 1838041 tagaacgtta ttgccgaagg agacaacaga aggacatgaa tcaccggatg gctatgtctc 1838101 ttgggtttta gcccaaagcg gaaccattcc cacaatgatc tcacataagc tcggattaaa 1838161 agggccaagc tattttgttc attctaactg ttcttcatca ctagtcggtt tatatcaagc 1838221 atacaaaagc ctgacatcgg gcgaatcaca atatgcgctt gtcggaggcg caacattgca 1838281 cgcacaatca gcgatcggct acgtgcacca aaacgggttg aatttttcaa gcgacgggca 1838341 tgtgaaggcg ttcgatgctt cggcggacgg aatggccgga ggtgaaggcg tagcagtcat 1838401 cctgctgaaa aaagctgtgg atgccgtaaa agacggagac catatttatg ccattatgcg 1838461 cggaataggc atcaataatg atggggcaga gaaggcaggc ttctatgcgc caagtgtaaa 1838521 aggccaaaca gaagtgatac agcatgtatt ggatacaacc aagatccatc ctgaaacggt 1838581 cagttatatt gaagcgcacg ggacgggaac gaaattaggc gatcctattg aaatgtctgc 1838641 tctaaataaa gtgtacaagc aatacaccga caaaacacaa ttttgcggaa ttggttcagt 1838701 gaaaacgaat atcggccatt tggatacagc tgcggggtta gccggatgta ttaaagttgc 1838761 gatgagttta taccataatg aacttgcacc gaccatcaac tgtacggagc cgaatccgga 1838821 tataaagttt gaaagctctc ctttttatgt tgtccgtgaa cgaaaatcgt tagagaaaca 1838881 cgcaggtgtc catcgggcgg ctctgagctc attcggcctt ggcggaacta acgcccatgc 1838941 aatatttgag caatatgaaa acatttctga tgcaggtgcc gaaaacgaag gcaatcagcc 1839001 ttacatcatt cctatatcag caaaaaatag tgaacggctc caagtatacg cgaaggaaat 1839061 gctgtcctat atcagtcaag acgagcaaag gcatttctct ttaagagata ttgcatatac 1839121 cttccaagtc ggccgtgaag caatggataa caggatcgtt tttatagtga acgatctgga 1839181 agagtggaaa catcagctgg aagcttttgt gactggaaag ccgctcgcag aaggctgtat 1839241 tcaaggagaa aaaacgagaa tgacatccgc tgaacagctg cttggaaatg ctgaagcaga 1839301 tgatatggct tcatcgcgga tatcaaaaga agaattgaga aagcttgccg agatgtgggc 1839361 aaatggcttt cacgttgaat ggcgcaggct ctatccaaat ataaagccac gccgcatcag 1839421 cttgccgaca tacccttttg ccgaagaacg atactggcct gaaagcagca ccggcgctat 1839481 cacaacaatt gaaccatctc gtttgcatcc tttggtgcac cataatacat cggttctgtc 1839541 agagcagcgt ttcagctcca ttttcacagg acaagagtat tttattgccg agcatatcat 1839601 taaaggcatg gcgattttgc cggcggcggt cacgcttgaa atggcaagag ccgctataga 1839661 acaaggaatt ggcggattgg aggatcatga aactggaatc aggctgaaaa atgtcgtgtg 1839721 ggttcgcccg gttgtagcag gaagtgagcc ggttcaggta aatatcggac tttacgatga 1839781 agatggcgga catattgctt atcggatgta tggtgatccg gaatccgctg atgcagaacc 1839841 agttgtatat aaccaaggta aagcggaatt gattcagtta aagcgagaaa aagcactgga 1839901 tctttctaag atcaagaaac aatgtgatca aagcaaaatg gatgctgcct cgttttatga 1839961 agggatgatc ggcgccgatt acggtccagg ttacaagagt gtagaggccg tatataaagg 1840021 cgacggccag ctgcttgcca aattatcact gccagaatct gttgcacata cgttgggcga 1840081 ttatgttctt catccaagtg taatggacgg ggcgttacag gcggctgaat atttgcaaaa 1840141 tgtcgtcaga gcggaacttt cagacactga agactttaag gcagcactgc catttgcact 1840201 ggaggaactt gaggtttttc gtcagtgcgt ttctgacatg tgggtttatg ttcaattcaa 1840261 ctcgaaaaac aaaccaggag atttgataca gaaagtcgat attcacctat gtgatgagca 1840321 tggcatgatc tgtgtgcggc tgaaaggatt ttcgacgaga gtgatggagg cagatataca 1840381 aaccgaacca tcaaaaatca acgctgaaac tttattgctt cagcccgttt ggcaagaaca 1840441 aaaggctgct aacagcttag ctgcaaaaaa atatgcagag catctcgtat tcctatgtga 1840501 atatgatcat gagacgagaa aacaaattga agcagccatc gaggatgtcc atgtatacag 1840561 cctggaagca aggccttctt cagtagatgg gcgtttccat tcttatacag aacaagtgtt 1840621 taaaaaggta caagagatca ttcgtacgaa accgaaagac ggcattctcg ttcagatcgt 1840681 gacctctgcc gagggagaac agcaattgtt ttcagggttg acaggactgc tgaaaacagc 1840741 ttgtcaggaa aatgccaaac taaccggcca aatgattgaa gtcagcagtg aagaaagtgg 1840801 agaaagcatt gctggcaaac tgttagaaaa tcaaatgagc agcgattcat atgtcaaata 1840861 tcaaaacggg acacggtata ttgctgattg gcgtgaaatc aaacaggcaa aaggagacgg 1840921 cagcaaaccg tggaaagaca atggcgttta tctcatttca ggaggtgccg gcggactagg 1840981 tcatattttt gcaaaggaaa ttgcggaaca aacgaaaaat gcgacagtca ttctggcggg 1841041 ccgctcacct cttagcgaaa gcaaaagcaa aaagctgaaa gagcttcata gcaagggggc 1841101 tgacatcacc taccggcaaa cagatgttac caataaaatt gaagtctatc agctcattga 1841161 cgacattcaa aaaagatatg gccgtctgaa cggtattctt catagtgccg gaatcatcaa 1841221 ggacagctac ctggttaata aacaggcaaa agatctgcac gatgtactgg cgcctaaagt 1841281 aaaagggctt gtttatctag acgaagcgag taaggatttg cctttagact tctttattct 1841341 cttttcatct ctttcaggaa gtttagggag cattggtcag tctgactatg cggcagccaa 1841401 tgtatttatg gatatgtatg caggctatcg aaataggctt gccgacctca gccagcggca 1841461 tgggcagacg ctttctgtaa actggccttt atggagagat ggaggcatgc aggtcgatca 1841521 agaaactgag aaaaggcttg tgcaacttgc cggtattgtt cctatgaggg cggaaaaagg 1841581 aattcaggca ttatatcaag cacttcattc agaggcaaac caagtaatgg tgatcgaagg 1841641 cgatgtgcag aaaataaaac aaaacatgct ggccaaaaac gcctcagcac ctatggaaaa 1841701 gaaggaagca gaacacatga ctgaacaaat aaatagcatt gatgcagaca gtttgctgga 1841761 taaagtaaag gcgatgttaa agcgagagat cgccaagctg ttaaaggtca agcttgaaac 1841821 gattgacgat catgcagaga tgacggtgta tggttttgat tctatctcca tgactgaatt 1841881 caccaaccat atcaatcgcg cctatcagtt agagctgacg ccaaccgtat tttttgacca 1841941 cccgacgatt catgcgtttg gcaagcattt gtcagaagaa tatcaatcgg tatttgcgaa 1842001 gacatttgct gtgcgcgctg tatcggctca gcttcagcct gctgcgaaac aggaacaagc 1842061 cgtgcgtgcc aaagctaaaa gacgcagaaa gcagcaagtc atgctgccaa acgccataca 1842121 gagtgatgct gggcctgagc caattgccat tgtgggcata agcgggattt tccctatggc 1842181 gaaagacgtt gaggcgtact ggaacatctt aaaagagggc aaagactgca tgacggaaat 1842241 cccgaaagat cgctgggatt ggcgtgaata tgaaggtgat ccggcgaagg aagtcaataa 1842301 aacgaacgtg aaatggggcg gttttattga cggtattgca gattttgatc cattattctt 1842361 tggcatttcc ccgcgtgaag ctgaacaaat ggaacctcag cagcgcttac tgctgactta 1842421 cgcctggaaa gcgatcgaag atgcaggata ttcggcgaaa aggttgtcag gcacaaaaac 1842481 cggcgtcttc atcggaacgg gaaatacagg atacagctct cttctatcta aagcgaactc 1842541 ggcaatagaa ggatcagcgg cagccaatac gagcccatcg gtcggtccga accgggtcag 1842601 ttatttcctt aatctgcatg ggccgagcga accggttgat acagcgtgct caagttcact 1842661 agtggcgatc caccatgcca tctcttcaat tgaggaaggc acttgtgaca tggcattagc 1842721 cggcggtgta aatacgatta tccttcctga ggtgtatatc agctttgata aggcgggagc 1842781 actgagcaaa gaaggaaaat gcaagacgtt ttcaaatcaa gccgatggtt ttgcacatgg 1842841 ggaaggtgcc ggcatactgt tcctgaaaaa attaaaagcg gctgaagaag cgggagacca 1842901 tatttacgga gtcataaaag gcagtgcaat caatcacggc ggccgtgcag cctctttaac 1842961 gactcccaat ccgaaggcgc aggcagatgt tattcagtcg gcatatcaaa aagcgggaat 1843021 cgacccgaaa accgtgacct acattgaagc ccacggaacc ggaacggagc ttggagaccc 1843081 ggttgaaatt aacggtttga aatcagcttt taaagcattg ggtgtaaatg aaggagacac 1843141 atcagccaat ccttactgcg gattagggtc tgtaaagaca aacatcggcc acttatcgct 1843201 ggcagccggt gcagcaggag ttattaaaat attattgcag cttaagcata aaaccttagt 1843261 gaaaagtctg cattgcgaaa acgtgaatcc atacattcag ctgaaaaaca gtccgttcta 1843321 tatcgtacgg gaaacggaag aatggaaagc gctgaaaaat gaacagggag aagagcttcc 1843381 tcgacgggca ggtgtcagtt catttggaat cggcggagta aacgcccacg tgattatcga 1843441 ggaatatatt ccggaagcat ccgatgagaa tataccatcc atcgcgccgg aacatccggg 1843501 tatcttcgtt ttatcggcta aaaatgaagc gcggctaaaa gaacatgcac agcagctggc 1843561 agatgcgctt gataagcaaa catatagtga cgtaaatctc gcccgaatcg cttatacact 1843621 gcaagccgga cgggatgcga tggaagaacg tctcgggatt atttccggtt ccattgagga 1843681 tttacagaaa aagttaaaag actttgcagc ggagaaaagc ggtgtggagg atgtatttaa 1843741 aggcaggatt gataaaggca cactccaaat gctgacagag gacgaagaga ttcaagaagc 1843801 cgtcgagaaa tggatggaac ggggaaagta tgcaaaattg cttgaattat gggtaaaagg 1843861 gcttgatgta gactggacga aattgtatgg cgagaatctg ccaaagcgca tcagcttgcc 1843921 gacgtatcct ttcgcaaaag accgttattg gatctctgat catattgaaa aaagcggcag 1843981 cattgatgca aatcaagcag cctcccgcct tggcggagcc gtgctgcatc cattaatgca 1844041 tcaaaacaca tccaatctct cggaacaaag gtttagctct atttatacgg gagaagagtt 1844101 tttccttgct gatcatgttg tgaaaggcca acggattttg ccgggagtgg ctcatcttga 1844161 attggcgcgg gcagctgttg agcaggccgc agaggtacaa ggtgtaccgc gcatcatgaa 1844221 gctaaagaat gcggtgtggg tgcggcctat tgttgtagag gatcagccgc agcaagtaca 1844281 cattaggctt ttaccgggag aaaatggtga gatctcttat gaaatctatg gtcattcaga 1844341 cgttactggc gaacagtcaa tcgtctacag tcaaggcagc gcggtattga atcctgctga 1844401 aaatttgccg gcggttgatt tgcaatctct gcgggagcag tgtcaggaaa gtcatttcag 1844461 cgtaaacgaa gtatacgaca cctatcgaat gattggattt gaatatggtc ctgcttatcg 1844521 cggagtgaaa aaaatctata cagctgaaca atttgttttg gcaaaattgt cattgcatcc 1844581 gtcagctgca gatacgctca gccaatacaa aatgcaccct gggctgatgg attctgcttt 1844641 gcaggcgtca agcattttga caggagccgg ggataaccag ctgacactgc cttttgcggt 1844701 ccaggagctt gaagtcttcg gagcatgttc gtcagaaatg tgggtatacg caagatacag 1844761 ccaaggcagc aaggcaactg ataaggtgca aaagcgcgat atggatattt tagatgagag 1844821 cggcaatgtt tgcgtacgga tgaaaggatt atctttcaga gcagcagaag gcggctctgg 1844881 atcggcggaa tctgatcaaa cgctggcaac cctgatgttt gaagaaaaat gggtgcccaa 1844941 ggattttaaa aaagaaagtc ctgagcctca ttacgaacgg cacattgtca tgctttgcga 1845001 catgaatggc ctctcaaaag atcgcattga atcaagaatg acaggagcgg aatgcatcgt 1845061 tttggagtca ttccgcgaag gacttgcaga gaggttccaa gattatgccg aacaagcgct 1845121 tgagacggtc cagggtcttc tcaaaagcag acctcagggc aatgttctga tccagctgct 1845181 tacctctgca caaagaaagc agtactcatt ctcagggcta tcggcgctcc ttaaaaccgc 1845241 cggcctggag aataaaaaac taatcggcca gacgattgaa atcgattcac atgaaaatgt 1845301 tgaaagtgta atagaaaaac tgaaagagaa taaaaggcac acagaagatc agcacatcaa 1845361 atatgaaaaa ggcaaacggt acatcaatga tctggatgaa atgcaaatag atgatcggga 1845421 aataagcatg ccgtggagag ataaaggtgt atacctcatc acgggcggcg caggaggact 1845481 tgggtttatt tttgcaaaag agattgctcg ccaagccgaa cagcctgtgc tcattctgac 1845541 aggcagatcc gcgttgaatg cggatcagca ggcggagctt aacgaacttc agcaattagg 1845601 ggctcgcgca gaatacaggc aggttgacgt gacacaaacg gaagcagcct ccgagcttat 1845661 cacaagcatt acgtctgatt acgaagactt gaatggtgtc attcacagcg ctgggctgat 1845721 taaagataac tatcttatga gcaaaaccaa tgaagagctg acacaagttc tcgctcctaa 1845781 ggtgaaaggg cttgtgaatg tggatgaggc aaccgagcat cttgcgttag atttctttat 1845841 cctcttttct tcaatatcaa gtgttgccgg cagcgcggga caggccgatt atgcaatggc 1845901 taatgcattt atggacagtt atgctgctta tcggaatgcg cttgtaaccg ccatgtacag 1845961 gcacggacaa acgttgtcaa tcaattggcc gctctggaaa gaaggcggca tgcgcgcgaa 1846021 taaagaaatt gaaaacatga cgttgaaaaa cacaggtgtg actccaatgc ggaccgagac 1846081 cggcattcaa gcgctgtata aaggtttggc atttggcaaa gatcaagtca tcgtcatgga 1846141 aggattcaaa gacatgatga gggaaaagct gactcaaaag ccgtcttctg atgatgtacc 1846201 aatgaaaaca gtgcaagtac gggtgacatc tgaagcaaga atggatcaag ggaatatgtt 1846261 tgaccacatt caagaagttt taaagcaaac aatctctcaa ttgctcaaaa tcaaacctga 1846321 agagattgac ccggacatgg agtttaatca atatggattt gattcgatta cgttaactga 1846381 attcgcaaat acactgaatg agaagtgcaa gctggatctt acgcctacgg tcttctttga 1846441 gcacgcaact gtttatgcat ttgcagggta tctgtcagaa gaatatccaa atgcttttac 1846501 agctcaaacg cctgccaaag ctgaggtgct gatgcagcct gtcgaacaga atataaaaaa 1846561 tatgacgttt tcgactgaaa accgctttgt aaaaccttcg gtaacaccaa tgcaaaagga 1846621 agctgatcac aagcctgagc ctattgcgat tgtggggatg agcggcgttt tcccaaaggc 1846681 aaaagacgtt gaggaatatt ggaagaacct gtcatcgggc gcagattgta ttacagaggt 1846741 tccaaaagac cgctgggatt ggcaggagta ttacggagac cctctgaaag aagcgaataa 1846801 aacaaacgtc aaatggggcg gttttattga tgaagttgct gactttgatc cattgttctt 1846861 cggcatatct ccgctggagg ctgagcagat ggagcctcag cagcgcctgt taatgaccta 1846921 tgcgtggaag gcggtagaag aagcgggaca ctcagcgaga agcctggcag gaaccaaaac 1846981 gggcatcttc atcgggacag gaaacacagg gtacagttca cttctgtcaa atgtagacat 1847041 cgaaggctca gcggctgcga atatgagtcc ttctgcagga ccgaatagag tcagttattt 1847101 cctgaacatt catgggccga gtgaaccgat cgacactgcg tgctcaagct ctttggtcgc 1847161 cattcatcat gcggtttgcg ccattgaaaa tggaaactgt gaaatggcga ttgcgggagg 1847221 ggtcaacacg gtcgtaactc cgcaaggcca tatcgcctat gataaagccg gggcgctgag 1847281 caaagaagga agatgcaaaa cattttctga caaagccgat ggattcgcag tcagtgaagg 1847341 tgccggcatt ctctttctga aaaagctgac agcggctgaa cgagacggtg atcatattta 1847401 cggtgtcatt aaaggaagtg cggtaaacca cggtggccgc gcaaattctc taacgactcc 1847461 taatccgaaa gctcaggcgg atgtcgtaaa aacagcatat gaaaaagcgg gaattgatcc 1847521 aagaaccgta acttatattg aagcgcatgg gactggaaca gagctgggcg atccagtaga 1847581 aatcaacggc ttaaaagcgg catttaaaga gctgtatgaa aaaacggggg acccggctgt 1847641 tcatggcagc cattgcggac ttgggtcagc gaaaacaaac atcggtcact tatcactggc 1847701 ggccggtgtg gctggtgtca ttaaagtgtt attgcagctc aagcataaaa cgcttgtcaa 1847761 aagtctgtac agtgaaactg ttaatccgta tatcagactg gatgacagcc cgttttatat 1847821 tgtgcaggaa tcgagagagt ggcaggcgct tcgggatgaa gccggccgag agctgccgcg 1847881 ccgcgcaggt atcagttcgt tcgggatagg cggcgtcaat gcccacgtgg tcattgagga 1847941 atatattccg aaagaaacaa cccatcctgc aacagcacca gccgtgacag cacagcaccc 1848001 gggcatcttt attttgtcgg caaaggatga agatcgtctg aaagaccaag cccggcaatt 1848061 agcagacttt atcagcaagc gatctatcac tgctcgtgac ctcactgata ttgcttatac 1848121 actccaagag gggcgtgatg caatggagga gagattaggg atcatcgctg tctcgactgg 1848181 ggacttgctg gaaaaactga acctctttat agaagggggc accaatgcga agtacatgta 1848241 cagaggcaga gcagaaaaag gtatcgcaca aacattgaga tcagatgacg aagtacagaa 1848301 aacgctcaac aatagctggg agcctcacat atatgaaaga ctgcttgatt tatgggtaaa 1848361 aggcatggaa ataggctgga gtaaactgta tgacggcaaa cagccgaaac gcatcagcct 1848421 ccctacctat ccatttgcga aagaacgcta ctggataacg gatacgaaag aggaggcagc 1848481 cgcccatcaa acagctttaa aaacagtcga atcagcagct ttgcatccat tgatacatgt 1848541 caacacatct gatttgtcag agcagcgttt cagctcggcc tttacaggtg ctgagttctt 1848601 tttcgccgat cataaggtga agggaaaacc ggttatgccg ggcgtggcat atcttgagat 1848661 ggttcatgct gccgttacaa gagcagtgag aagaaccgaa gatcaacaat ctgttattca 1848721 catcaaaaat gttgtgtggg tgcagccgat tgtggcggat ggccagcctg ttcaagtgga 1848781 tatcagtcta aatccccagc aggacggcga gattgctttt aacgtctata cagaggctgc 1848841 acacaatgat cgaaagatac attgtcaagg cagtgcttca atccgtgggg caggagacat 1848901 tccagtccag gatatcagcg cgcttcaaga ccaatgcagt ttaagcacac tctcacacga 1848961 ccagtgttat gaattgttta aggcgatcgg cattgactac ggacctggtt ttcaagggat 1849021 agatcggctt tacatcggcc gcaatcaagc cttggcagag ctttctctgc ctgctggtgt 1849081 aactcacaca ctgaatgaat tcgttcttca tccaagtatg gccgactctg ctttacaagc 1849141 gtcgatcggg ctaaagctga attccggtga cgagcagctt tctctgcctt ttgcgctgca 1849201 agagctagaa atattcagcc cgtgtacaaa taaaatgtgg gtgtctgtga catctcgtcc 1849261 taatgaggac aaaatacaga gactggatat tgatttgtgt gatgaacaag gccgagtgtg 1849321 tgtaagaatc aaggggatta cctcaaggct gctggaagaa ggcatacaac cgccagacgg 1849381 gccgacatca ctaggaaact ccaaagcaac tcttaacgga gcgcttctta tggcgccgat 1849441 atgggatcga gtgcagctgg agaagaggag catttcgcct gctgatgagc gtgttgtcat 1849501 cctcggaggg gatgacaaca gcagaaaagc tgttcaaagg gagtttccgt ttgccaagga 1849561 gctgtacatt gagccgaacg catcaattca tagaattaca ggccagcttg aagcactcgg 1849621 atcgtttgac cacatcgtgt ggatgtctcc ttctcgtgtg acagagtgcg aagtcggcga 1849681 tgaaatgatt gaagcccaag atcaaggcgt cattcaaatg tataggctca ttaaggcaat 1849741 gctttcttta ggctatggac agaaggagat aagctggacg atcgtgacgg tgaacacaca 1849801 atatgttgat cagcatgata ttgtcgaccc ggtcgatgcc ggggtgcacg gcctgatcgg 1849861 ttcaatgtca aaagaatatc caaattggca gacaaagctg atcgatgtta aaaaatacga 1849921 agacctgccg ttatctcaac tcctttcctt gcctgccgat caagaaggga atacgtgggc 1849981 ctatcgaaac aagatttggc ataagcttcg tctaattcca gtacacaaca atcaaccggt 1850041 gcacacgaag tataagcacg gaggtgttta tgttgtcata ggcggagctg gcggtattgg 1850101 tgaggcgtgg agtgaatata tgatcagaac atatcaggcg cagatcgttt ggattggcag 1850161 aaggaaaaag gatgcagcca ttcaaagcaa gctggacaga tttgcacgtc tagggcgagc 1850221 cccgtattac attcaagcag atgcggctaa ccgagaggaa ttagaacgcg cgtatgaaac 1850281 aatgaaacaa acacatcgtg aaatcaacgg catcatccat tctgcaattg tcttacaaga 1850341 ccgaagcctg atgaatatga gtgaggaatg tttcagaaac gttcttgctg caaaggttga 1850401 tgtaagcgtg cgaatggctc aagttttccg gcatgaacca ctggattttg ttttgttttt 1850461 ctcttccgta caatcgtttg caagagcttc cggacaaagc aattacgctg cgggttgcag 1850521 ttttaaggat gcttttgcac agcggctttc tcaagtatgg ccttgtacag tagccgtgat 1850581 gaattggagt tattggggaa gcattggtgt tgtttcatca ccggattacc aaaagagaat 1850641 ggctcaggca ggcataggct caattgaagc ccctgaagca atggaagctt tggaattgct 1850701 gctcggggga ccgctgaagc agctagtaat gatgaaaatg gcaaacgaaa cgaatgatga 1850761 agcggaacag acagaagaaa cgattgaagt gtacccggaa actcacggct ccgccattca 1850821 aaagctgcga agctatcacc cgggtgacaa cacaaagatt caacaactgt tataggaggg 1850881 gaaacgccaa tgctgaacac agaagacatt ctctgtaaaa tgcttttcgc acaattacag 1850941 tccatagggt ttttcacaga aagtaaatcc cagccggtat tggagaattt ctatggcaga 1851001 tggtttgaag aaagccaatc gattttagaa cggcatcaat ttctcaagcg aacggagaac 1851061 ggacatgttc caacacgctc aataggcacc atgagcgagc tgtggaaaga atggaatgaa 1851121 caaaaatttg acctgcttca agacaataat atgaaagcca tggtgacatt ggtggagaca 1851181 gcacttaaag ccttgccgga gattctgacc ggcaaggcgt cagccaccga tatcctgttt 1851241 ccgaattcat ctatggattt agtagaaggg gtctataaaa acaatcaagt cgcagactat 1851301 tttaatgatg ttcttgcaga tacgttaaca gcctatctgc aagaacgtct gaagcaagag 1851361 cctgaggcga agattcgaat attagaaatc ggagccggga ccggcgggac aagcgcggct 1851421 gtttttcaaa aattgaaagc atggcagaca catataaaag aatattgtta tacagatctg 1851481 tctaaagctt ttttaatgca tgcagaaaat aagtatggtc ctgacaatcc atatttgaca 1851541 tataaacgat ttaatgtcga ggagccggcg tctgaacagc atattgatgc gggaggctac 1851601 gacgcggtca tcgcggcaaa tgtgcttcat gccacaaaaa atatccggca gacattgcga 1851661 aatgcaaaag cagttttgaa aaaaaacggg ctgctccttt taaatgaaat aagtaatcat 1851721 aatatatatt cgcatttgac gttcggcctt ttagagggct ggtggctgta tgaggatcct 1851781 gatctccgca taccgggctg cccgggcctg tatccagaca cttggaaaat ggtgcttgag 1851841 agtgaaggat ttcgctatgt ttcctttatg gctgaacaat cgcatcaact cggccagcag 1851901 atcattgccg ctgaaagtaa cggagtcgtc cgtcaaaaga agagaacgga ggcagaagaa 1851961 gatccaagcc atatacaaat gaatgctgaa atcgatcatt cacaggaaag cgattctctc 1852021 atcgaacaaa cggcacaatt tgtgaagcat acgctggcaa aatcaatcaa actatcacca 1852081 gaacgtattc acgaagatac gacatttgag aagtatggaa ttgattcgat tttgcaggtg 1852141 aatttcattc gtgaattaga aaaagtgacg ggagagcttc caaaaaccat tttatttgaa 1852201 cataacaaca caaaagaact cgtcgaatat ttagtaaagg ggcatgaaaa taagcttcgg 1852261 acagcattgt taaaggaaaa aacgaagcct gcaaaaaatg aagctccact tcaaacagag 1852321 cgtacagatc ctaataagcc atttactttt catacacgcc gctttgttac agagcaggaa 1852381 gtcacggaaa ctcagctagc aaataccgaa ccactaaaaa tagaaaagac aagtaatttg 1852441 caaggaacac attttaatga ttctagtaca gaagatatcg caataatcgg ggtaagcggg 1852501 cgctatccga tgtctaacag tttagaagag ctttgggggc atttaatcgc cggagacaat 1852561 tgtattacag aggcaccgga atccagatgg cgcacatctt tattgaaaac attatcaaaa 1852621 gatccaaaaa agccggcaaa taagaaacgc tatggcggat ttttacaaga tatagaggca 1852681 tttgaccatc agctttttga ggtggagcaa aaccgggtga tggaaatgac accggaactc 1852741 cgtttatgtt tagaaaccgt ctgggaaacg tttgaggacg gcggctatac gcgaacccgg 1852801 ctggataaat tgcgggatga tgacggagta ggtgttttta tagggaatat gtataaccag 1852861 tatttttgga atatcccatc tttagagcag gcagtcctca gctcaaatgg gggagactgg 1852921 cacattgcaa atcgcgtttc ccactttttt aacctgaccg gaccgagtat cgctgtcagc 1852981 tcagcatgct ctagttcatt aaacgccata catcttgcgt gtgaaagcct gaaattgaaa 1853041 aactgctcaa tggcgattgc tggaggtgtc aatttaacac tcgatctctc taaatatgat 1853101 tctttggagc gtgccaatct gctgggaagc ggcaatcaaa gcaaaagttt tggcaccgga 1853161 aacgggctta ttcccgggga aggcgtcgga gctgtcctgt taaaaccact ttcgaaggcg 1853221 atggaagatc aggatcatat ttacgctgtg atcaaaagca gttttgctaa ccatagcggc 1853281 ggaagacaga tgtatacagc tccggacccg aagcagcaag caaagttaat tgtcaagtcg 1853341 attcagcagt cgggcattga tccagagact atcggctata ttgaatcggc ggcaaatggt 1853401 tcggcgctgg gcgatcctat tgaagtaatt gccttaacaa acgcgtttca acaatataca 1853461 aacaagaaac agttttgtgc gataggctct gtcaaatcca atctggggca tttagaggcg 1853521 gcttccggta tttctcagct gacaaaagtg ctgctgcaga tgaagaaagg gacgctggtg 1853581 ccgacaatta acgcgatgcc tgtcaatcca aatattaagc tggaacacac ggctttctat 1853641 cttcaggaac aaacagagcc atggcatcgc ttgaatgatc ctgaaactgg aaaacaattg 1853701 ccgcgcagaa gcatgatcaa ttccttcgga gcggggggag cctatgccaa tcttattata 1853761 gaagaatata tggagacggc ccctgagaaa gaacatatcg ctccccgcca gcaggaattc 1853821 actgccgttt tttcagccaa aacaaaatgg agcctgctta gctatctaga aaatatgcaa 1853881 ttgtttttag agaaggaagc ttctctggat attgaacccg ttgtacaggc tttacacagg 1853941 agaaaccata atttagagca taggactgca tttacagtgg catcgactca agagctgatc 1854001 gaaaaactaa aggtgttccg aacatcaaga gaaagctcac tccagcaagg catctataca 1854061 tcattcgatt tacagccatg tgcggaatca gcatctaggg atagagaaat aaacgcagca 1854121 gagcaatggg cacaaggggc attgattgct tttaaagaag ctgatatagg gaaccgaaca 1854181 ggctgggttc atctgcctca ctatgcattt gaccataata catcatttca tttcgatgta 1854241 tcgtctatca atgagaaatc gtcagatgtt gaagacaata tcaatcagcc ggtcattcaa 1854301 gatcaattca cttatgatga gccttacgtt caaggacacg tcttcaacaa tgaacgggtg 1854361 cttgtcggtg ccacatatgg cagtctggcc attgaagcat tttttaacct gttccctgag 1854421 gaaaacagcg gccgtatcag caaattaagt tatatcagtc caattgtcat caaacaaggc 1854481 gagaccattg aacttcaggc aaagccgctg caaaaagatc aagtcataga actgcaaatc 1854541 atgtatcgcg agccgtcctc tggtttgtgg aagcctgccg caatcggaca atgcggaatc 1854601 ggttcttttg agcccaaaaa agtcaatatc gagaacgtta agcattcatt aactaagctt 1854661 catcacatcg atcagatgta taaaaccgga aacggtcctg aatggggaga gttatttaag 1854721 acaattactc atctctacag agatcacaag tctatactgg caaaaattcg cctgccccaa 1854781 agcgggctgg caaacgggca ccattacact gtaagcccat tgatgacaaa cagcgcgtac 1854841 ttggctatcc tcagtttctt agagcagttt gacatgacag gcggcttcct gccgtttgga 1854901 atcaatgata tccagtttac aaagcaaacg ataaaagggg attgctggct tttgattaca 1854961 ttggttaaga atacaggtga catgttgctg tttgatgtag atgtgatcaa tgagtcgtca 1855021 gaaacagtgc tgcactactc gggctactcg cttaaacagc ttcgtatttc gaatcaaaga 1855081 ggaaatcaaa ataaggccat caaagccagc aatctgaaag ctcgtatcag aagctatgta 1855141 acagataaac tggcagtaaa catggccgat ccgtcaaaat tgtcaattgc aaaagcgcat 1855201 atcatggatt ttggaattga ttcttctcaa ttggttgcac tgacaaggga gatggaagca 1855261 gagacaaaga tcgaattaaa tccgactctg ttttttgaat atccgactat tcaagagtta 1855321 atcgactttt ttgcggacaa acatgaagca tcttttgctc agctgtttgg tgaagctcat 1855381 cagcaggaag aacgcccagc tcaaatcgaa aaccaaatga aacagattcc ggcatacgag 1855441 acgaacacgg ataaaacaat cgaacacgcg gcagacggca tagccattat cggcatgtcg 1855501 ggacagtttc cgaaagcaaa cagcgtaacg gaattttggg ataaccttgt ccaaggaaag 1855561 aactgtgtct ctgaagtgcc gaaagaacgc tgggactggc gcaaatatgc cgcagccgat 1855621 aaggaagggc aatcaagcct tcaatggggc ggttttatag aaggaatagg tgagtttgat 1855681 cccctgtttt ttggcatatc gcctaaagaa gcggcgaata tggacccaca ggagtttctg 1855741 ctcttgatac atgcatggaa ggcgatggaa gatgcaggct taacagggca ggttttatcc 1855801 agccgcccga caggagtatt tgtcgcagcc ggcaatacgg atacagctgt ggttccttcc 1855861 ctaattccaa accgtatatc ctatgcactt gatgtaaaag ggccaagtga atattatgaa 1855921 gctgcctgtt cctcagctct agtggctttg cacagagcta tacaatccat tcgaaacggc 1855981 gaatgtgagc aagccattgt cggggctgtg aatttgctgc tttcaccaaa aggctttatt 1856041 ggcttcgact caatgggcta tttgagtgag aaagggcagg ccaaatcctt tcaagcagat 1856101 gcaaatggct ttgtcagaag tgaaggagca ggagttctca tcattaaacc attgcaaaaa 1856161 gccattgaag attctgatca tatttattcg gttattaaag gttcaggtgt atcgcatggc 1856221 ggcaggggaa tgtcacttca cgcgccaaat ccggccggca tgaaggatgc aatgctgaag 1856281 gcttatcaag gagcgcaaat tgatcccaaa acggtgacct atatagaagc gcatgggatc 1856341 gcctctccat tggcagacgc gatagaaata gaggcgttaa agtcaggctg cagtcagctc 1856401 gaattggaac ttccacagga agtacgggag gaagcgccat gttatatcag cagcttaaag 1856461 ccgagcatcg gacacggtga actcgtctca ggcatggctg ctcttatgaa ggtcagcatg 1856521 gcgatgaagc atcaaacaat accaggcata tccggatttt cgtctttgaa tgaccaggtg 1856581 tcattaaagg gcacccgttt ccgagtgact gccgagaatc agcaatggag ggatttaagt 1856641 gacgatgcag gcaaaaaaat tccgcgcaga gcgagtatca acagctatag ctttggaggc 1856701 gtaaatgcgc acgtcatttt agaagaatat attcctttac caaaaccacc ggttagtatg 1856761 agtgagaatg gtgcccacat tgtagttctt tctgcaaaga atcaagacag gctaaaagca 1856821 attgctcaac agcagcttga ctatgtgaat aaacaacaag aactgtcatt acaagattat 1856881 gcttatacac ttcaaaccgg ccgagaggaa atggaagacc gcctggcgct cgtcgtccgc 1856941 agtaaagaag aactggtaat cggcttgcaa gcctgcttag cagaaaaagg cgataagctg 1857001 aagagttctg tacctgtctt tagcggaaat gcagaaaatg gctcgtcaga tctcgaagcc 1857061 ttgctggatg gtccattaag agaaatggtg atcgagactt tgttgtctga aaacaacctt 1857121 gaaaagatcg cgttttgctg gacaaaaggg gtgcaaatcc catgggaaaa gctttatcaa 1857181 ggaaaaggtg cccgcagaat accgttgcca acctatccat ttgaaaagag aagctgctgg 1857241 aacggctttc aagcagtaga gaatacgcct tctgtttcac aggatgagcg tatcaacaac 1857301 agcagcgatc atcacatatt agcaaatgta ctagggatgg ctccggatga actgcagttt 1857361 cataagccat tgcagcagta tggatttgat tcaatttctt gcatacagtt attacagcaa 1857421 ttgcaatcaa aggtggaccc tctcattgtc ttgacggagc ttcaagcatg ccatactgtt 1857481 caggacatga tggacttgat cgcaaagaaa caggaggata catccttaca aaatgatcaa 1857541 gctcgcacgt ttccggaatt aataccgtta aatgacggca agcgggggcg ccctgtcttt 1857601 tggttccatg gcggagtagg aggagttgaa atctatcagc aatttgcaca aaagagccag 1857661 cgcccttttt acggcattca agccagagga ttcatgactg attctgctcc tttgcacgga 1857721 attgaacaaa tggcttccta ttatatagag atcattcgat ccatacagcc tgaaggtcct 1857781 tatgatgtag gcggatattc cttaggcggg atgattgcat atgaagtcac tcgccagctg 1857841 caaagccaag gccttgctgt caaaagcatg gtgatgattg actccccata tcgttctgag 1857901 acaaaagaga atgaggcatc tatgaaaacg tcaatgctgc aaacaattaa tacgatgctg 1857961 gcatcgattg cgaaacggga aaagtttacg gatgttctca tcagccgtga agaggtggac 1858021 ataagcttag aggatgaaga attcctgtct gagttgattg acttggcaaa agaacgaggg 1858081 ctaaacaaac cagataaaca aatacgtgcg caggctcagc aaatgatgaa aacacagcgc 1858141 gcctatgatt tggagtcgta cactgttaag cctctccctg atcctgagac ggtaaaatgt 1858201 tattatttcc gcaacaaaag caggtctttc tttggtgatt tagacactta tttcacttta 1858261 tcaaatgaaa aagaaccgtt tgatcaagct gcctattggg aggaatggga gcggcaaatt 1858321 cctcatttcc acctggtgga tgtcgattca agcaaccact tcatgatatt aaccgaaccg 1858381 aaagcgtcaa cagccctgtt agaattttgc gaaaagctct attcaaacag gggagtagtg 1858441 aatgcgaatt tccttaaggc tttccggaag aaacatgaag cgagggaaga aaaagaaaca 1858501 gatgaattgg tgaagcgctg agaaaacaca aacgccccct cttttaaaag ggggcgtttt 1858561 gaatgttatt ttgaaagtga aacagggaga ctttctaatc ctcttaaaaa gacatttttt 1858621 ctccattgaa tgtcatcagg tgcaaccgca agttcaatat caggaaatct cttcaaaagt 1858681 gctttaaatg caatgtggcc ttccagcctg gcaagaggcg ctcctaagca gaaatgaatg 1858741 ccaaaaccaa aagaaatatg tctattaggc gaccgattta tatttaatat ttcggggttc 1858801 tcaaaaaaat tcgggtcgcg attggcagat ccgatgccta taaaaatcat gtctcctctt 1858861 ttgatcgaat gccccttata tgtaaagtct tcgatggccc accgatttgc catcataacg 1858921 acaggtgagg tgtatcgcag caattcttca accgctgtag cgatcatttc aggctgctgc 1858981 ttgagcttct cacattcctt cttgtgctgc agcaatgcga gggtgcctga gccgagtaag 1859041 ttaacagttg tttcaaggcc ggctacaacg agcaagaaca gcatcgaata gagctctttt 1859101 tcgcttaact tgctgccgtt ttcctcagca tgcacaagtt tgctgattaa atcgtctttt 1859161 ggctttattc ttctgtcatg gatcagctta gcgatataat ctttaaattc acgaagggcc 1859221 tgatttgtca gctctctatt accttcagag gtatcaacca tcgcattggt ccagatttga 1859281 aactgtgacc gatcttcttt tgggattccc atcaattcag atataacaat aaaaggcaaa 1859341 ggggaagcga aggatttcat gatatccgct ttattttctt tttccatttc atctaaaagc 1859401 tgttcagcaa tttgttcaat gctgccgcgc agattttcaa tggttcgggg agtaaatgct 1859461 tgatgaacaa gtgatctcag gcgggtatgg tcaggtgtgt cttttgccag catatgatcg 1859521 gatacaaaat cgatatcttc actaacgttg agcattttga tttgttcttg gttcatcaca 1859581 ttttttacgt ctcttgtaat tcgattgtct tttaaaaagg ccatacaatc atcgtatcgg 1859641 gtaattaacc aggccggata tgtggctccg aaccgtttta attcaaatcg gtgaatgggc 1859701 tcttcctctc taaatcgtcc taaaactgaa aaaggattgt gatgaaactc tttaccatgc 1859761 ggatgaaaca tcaatttttc catttgcatt ctcctcgcct aatagggtaa atagatgaat 1859821 caaattgctg aattagttta caaaaaacag aatgatttga aatgtaatcc tgtctctaaa 1859881 actatatatc tatcttaggc gtcattcaat agggagaaga acgaaaaaag tgaaaaaacg 1859941 gctcgatata aagcagcgcc tttgaacgaa agctcaaagg cgctacgctg tattattttg 1860001 atgaaagtgg ctgtcagctg tgctggatat caattgtata tactgcacga tctgttacga 1860061 ccttcaatcc ttcgttttct tggtgaatat gaagctcacc taataaagga atctcatagg 1860121 cattttgcgg aagcggtacg tttccgtcct cagtgaatgt tgttccttcg ccttctaaaa 1860181 caagctcttc tttcgcaaca taatcatcag gatgattcgt actgcgtata gccacttttt 1860241 gaaggtggag aacaatctga tccaagtctg atatctcttc atcatgggtc aattcacctt 1860301 ttctaatatc aagcgtctgg ccgacttttg attccagcca ttgagaaagc tgtgtattcg 1860361 tgtgtgccat caatattcct ccttttgatc tacacgatac tattcccaat tgctgcatct 1860421 tttacacggg aaagagccgc cccactcttt atgtatgaaa cagttcgctg ttgagtgcct 1860481 tgatatagcg tacggcagaa cgctggaccg attcgtcggc attttctttg acaactttag 1860541 agaaagcatt gtaaagccgg ttgaattgaa gcggttttac tttggctgct atttcttcaa 1860601 ctttggaggc gggaagggga atgagatttg ggtagctgta cataaagctg acccagtttc 1860661 gatccgccgc aaccgtaatg atatctccgg tcaatagaca gcctttccct tcattgccct 1860721 tgctccaatg caaaacagca ccgcctttaa aatgtccgcc cagtcggtaa aggtccagtc 1860781 ccggcttcat attgagcgtt tcccctgacc agaagtgaat gtgattgctt ggccttgtca 1860841 cccattcttt atcatcctca tggatataga tcggcgcctg aaacgcttca gcccactcaa 1860901 cctgagtaga gtaataatgt ggatgagaca aggcgatggc ttgaataccg cctaattcgt 1860961 tgatttggtc aattgtcttt tggtcaagat atgtcatgca atcccacagc acattgaagc 1861021 ccttatgctg aataagatgg gctgtttgtc caatcgcaaa ctctggttca gttttgatgc 1861081 tgtaaagatg ctcttcttcc tttttaagga tgttttgaag gtttcctttc tcacgcatgt 1861141 cttcaagggt tgtccaagtt tgtccatcgg gatgaatata ctgtctttca tcctcgcaaa 1861201 tcagacacga gttgggcgga tctacagtct gtgcatgttg cacaccgcat gtattgcaga 1861261 tataatatgg cactttcttc acttccttca tctattttcc attattttac cttatgatta 1861321 tgaatattca aacgaaaaaa ccggcagttc tgctgagaga gaattgccgg cttttgatga 1861381 tgtttattgg ccgggaacgg aattttctgc gttgacagcg cccgctccgt agatattcgg 1861441 atcttcatct ttccatttgt ccgtgccgtt tttcaaaagc tcttttactt catcaggggt 1861501 aagatccggg ttttgctgaa gaattaaagc tgcgattcct gcgcaaatcg gtgttgccat 1861561 cgaggttcct gacattgtaa agtactgaga ccctacacgg cttgactttt ggagcttatc 1861621 aatataagaa ttcggagagc gaagggaaat aatattaaca cccggcgcta aaatatcggg 1861681 cttttctttc ccgtatactg tcgggccgcg gcttgagaag gaagcgacag tatcatcatc 1861741 gctgcttgca gtattgttat cgtcaagcgc acctactgta atcacctttt cgctcacgcc 1861801 cgggcttgca atggtctgcg aatcagggcc tgagtttccg gcagcgacac agacgacaat 1861861 ccctgcgctc cacgcttcct caaccgctct gactaacgga tcttcctgtt catgatcata 1861921 tctaagggca tcgcccccga gcgacatgct cataatatca atcggttcat cggggttgtc 1861981 ctcattgtat tgaatacacc actcaacacc ctctataata tctgctaacg ttcctgaacc 1862041 ctgcttgttt aataccttta cgccgatgag attggcttcc ggtgcaggtc cgcggtattg 1862101 accggaagag gatgcaccgc tgcttgcgac atcacctgca cagtgtgtgc catgaccatt 1862161 atcatcgtac ggctctgttt tttgattgac catgtccgcg aatccgataa ttcttccttc 1862221 tagatcagga tgcgggtaga ttcctgtatc gacaacagcg acagtaacac cttttcctgt 1862281 cagggtttgc ccgtttctga cgacttcctt cgcatggctt gcttcggttg ccgtgtctaa 1862341 aagcgctttg acttcgcggt ttaaatacac tttacggata ttgctgcatt cagagagaag 1862401 ggaatgtaat gctgaaggag taacctcggc gctgcagcag ttgattttgt tgaagcggct 1862461 ttttagcttg ctgcgttttt ctttttgcag cacctctcca gccatttgaa agccggtctc 1862521 gtgacagcct tcctcaaatt cgataatgac tgacattttt tttctgtttt gcaatttggt 1862581 ttcgaaaaat ttatgcaaga agcaaggagt ccatttgaag ggcttgtaaa gttgcaatac 1862641 ggtttcccgt aacggccaat ctagcttgtg agcatttgct ctcaccattt gtaccataga 1862701 gtacccaaac atgtattttc ctcctattat aaggttctct gtatactcta tgaacagatg 1862761 ataggtttgg taagtttgtt tgtcctctgt aagagacaga caagagtttg tttttctgaa 1862821 tctttcgcat tagatacgat agattcagaa gctgaggaaa tcattgggga ttgaaaaaga 1862881 acgtttgttc gtattataat gtgatcatat caaactggga aggggagagc aaccgtatga 1862941 atttctactt gcaccgatct ttggaaagcc aaatgccaat cagcattata tatgaagaaa 1863001 gacggaacga ttagtaaaag aacgattatt gtgagacaga aaagcaaaac gaaaatcaaa 1863061 gcattttgtt tttcgaaaca acagatcaga acatttttat tggactctat cctctcctgt 1863121 gattttgtga gaacaaataa gcaaaatctc tattctgcag gccggtaaca gctgtccgtc 1863181 tcagcaaccg ggcagcctgt tactaaaacc ctccttaaac ctatatacat ttatttgcca 1863241 agtgaggttg ttcctacctt ttttgtcttt cctctcaacc ttttttcact cttatttgaa 1863301 atgaaccgct aataaccgtg acaatcaatt gattttttga aaccgggaac tttttcactg 1863361 atgatattgt gtatacaatg gtaagataaa acctattggc taaacctcat ataatgaacc 1863421 gcgccattct tatgaaagga gttaaacatg agaagatttt tactaaatgt catattagtc 1863481 ttagccattg tcttgttctt gagatatgtt cattactcat tggaaccaga accatcaaat 1863541 cagccagata catattcaaa tttcagcagc ttggcagaga atgagagccc agccgattac 1863601 gatatttcat ataatgagaa aaaaggaagc aaagtcttaa ttatgtctcc gcatggcgga 1863661 agaattgaag gcggagtaag tgagcttgtg cgttatttca ataatgaata ctctacatac 1863721 ctatttgaag ggttgaagtc ccatgataac caaacactgc acattacaag caccaacttt 1863781 gatgagccat tggcaaaaaa gaaaatcaag gagcatcaat atgtggtggc ttttcacgga 1863841 tataaaggag agaacaagaa tacccttgta gggggaacag accgaaagcg ggcgaaaatg 1863901 attgtgagag cccttgagcg gagagggttt tccgctgagt tagcgtcgtc taaaagcggt 1863961 cttgctggat tgaatgccga aaacattaat aaccaagggg aaacggggct aagtatccag 1864021 ctggaaatca gccgtgagca gagagaagca ttttttgatg atttttatta taaaaataga 1864081 aaatacacaa agaacagtga attttatgct tatgtcagtg cgatcaaagg tgtcctggaa 1864141 aaagagtatt cgtaacaagc agatcagaag acaaaataag agaagatcag tagactgaaa 1864201 taggataaaa aaggaggcaa aacaatggca gatcatcatt tttatttaaa agcgaactgg 1864261 ccgggtaacc gtaatgatgt cggtacgatc gaaagcggaa acctgatcac atcgatttcc 1864321 attcctaaag aaatggatgg cccgggagaa gggaccaacc cagatgaaat gcttctcggg 1864381 gcggcagcga cctgttacat tattacactt gcagcgatga tggagagaag cgggctggaa 1864441 aaagaagact tacagatgga gtcagaaggc attgtcaacg ttacaaaagg agtctttaca 1864501 tacaaaaaga tcattcaccg tccctctgtc gtgcttaaac atgatgcttc acaagacgac 1864561 gtcgcattgg cgcacaaact ttgtaaaaaa gcggagtcgt catgcatgat ttcgcgtgca 1864621 attcaaggaa atgtcgagct gcagcttgaa gcctctgtga aactgggtgg agaataaaga 1864681 aaacagacgg tcactcacag gccgtctgtt ttttatcttc agcgtgggct ttcgattgat 1864741 ttagcacgac cacgcctgca atgacaagcg tgagaccgaa tacacctttt aaactgatgg 1864801 tttcgccaaa aagcaaaaac ccgacaattg ctgtaagcgc ggtaccaacg cccgaccatg 1864861 ttgcatacgc gcttgataag tcaattgttt ttaaagaaaa gcttagaaac gtaaaagcag 1864921 aaagaaatcc gactatgact ccggcaatgg gccaggcttg tgtaaatcct tctgaaagct 1864981 tcaacatcgt gctcccaaac acttcagata caatggcgag agccaaataa agcaatcctc 1865041 tcatcttcat cactccttta cggccaatta agtaacacga cccctgatag taataaaaga 1865101 atcccgataa gccctttggc attcagatct tccttgaacc attttactcc gatcactgtc 1865161 gtcagcaccg tgcctgcccc gctccaagtc gcataggaga ggctcagggg aatatggttt 1865221 aaagtcaggg acagcatata aaaggcgagg gaatagccaa taacgaccaa agcacttggc 1865281 ttccactttt tgaagccatc agatactttc agcatggctg ctcctatcga ttccgaacat 1865341 atggcaatcg tgaggaatat atatcctatc aacatcatga attctcctca ctatattttt 1865401 agattagaaa aaaaacttca gctagaaaaa tattagtgta tgcctatgta tgagtcaaga 1865461 gattcatttt cacacactta aaaagacccc tttttaaggg gtcttttgcg tttaataata 1865521 aaaagggaac ggggcatacg gataataggg gtatccgcca tacaaataag gattaaataa 1865581 agcgcttcct ataagcccgc ctgcaaggcc gccgataaac ggtcctccaa aaaatccgaa 1865641 tggccggcca aacccataac caaatccggg tcttccaaac ccgtaaccga acccgaacgg 1865701 tcttccaaac ccaaatggtc tcccgaatcc gaacggcctt ccaaatattc ttgtatcttc 1865761 agggctgaaa tgctctaact cgttcatgtt ttctttcctc ctgtaataaa gtgtagatga 1865821 tgcagtgtat tcaccctgcc cggatttgat tgggcgaatc gaggaaaagg aggatgtgaa 1865881 cacattgggc ctgtatcagt ctgactggtc aaaagcaccg ccccacgcac atgcttatca 1865941 tgtcaaaaca acgagagaac agggccatta tcatctcatc gaagggttta ctcagccggc 1866001 aaacggatca aataccgatc agcatacaca ttactataca gggatcactt catttgaaaa 1866061 cggccatttt catcggtatt acggaatctc aggaccggcg attcccttag cagatggcac 1866121 acattatcat gaaatcgaag aaacgacgta tctggcctat aacgagccga ttgagatcca 1866181 gtacggaggg gttgtgtacg atcccggaga tgacagaaga aaaacgcatc gtcataccct 1866241 gaaaggaaag acaagggaaa ttgtcggcaa tgagccgctc ggctggtaga aggatgttta 1866301 ccgatgcaaa aaaagggcaa aatggatagg tggttgtcca tgttgaatgc tataatgggg 1866361 ggagatttat aaaagagagt gatacatatt gaataatacg aagcagcccg ttgtcatttt 1866421 agtcggaccg acggcagtgg ggaaaaccaa tttaagtatt cagctagcca aatccttaaa 1866481 cgcggaaatt atcagcggag attcgatgca gatttataaa gggatggata ttggaacagc 1866541 taaaattacc gaacaggaga tggagggagt gccccatcat ctgattgaca ttttagatcc 1866601 ccaagactct ttctctactg ccgattatca aagcttagta agaaataaaa tcagcgagat 1866661 tgcaaataga ggaaagcttc cgatgattgt cggcggtaca gggctttata tacaatctgt 1866721 gctttacgat tatacattta cggaagaggc aaatgatccc gtgtttcgag agagcatgca 1866781 aatggctgct gagcgggaag gcgctgactt tcttcatgcc aaacttgctg cagcagatcc 1866841 cgaggcagca gctgcgattc atccgaataa tacaagaaga gtcattcgcg cactggaaat 1866901 tttacatacg tccggaaaaa cgatgtccca gcatttgaag gaacaaaaac gagaacttct 1866961 gtacaatgca gtgttaattg gcctgacaat ggatagagac acgctttacg aaagaattaa 1867021 tcagcgggtc gatttgatga tgcagtcagg ccttcttccg gaagtgaaac gcttatacga 1867081 caagaacgtg agagactgtc aatcaataca ggcgataggc tataaagagc tgtatgcata 1867141 ttttgacggt tttgtgacac tttccgatgc tgtcgaacag ctaaagcaga actcgaggcg 1867201 gtatgcgaaa cgccagctga cgtggtttcg caacaaaatg caggtcacat ggttcgatat 1867261 gacaccgcct gttgatatgg agctgaaaaa aaaggaaatt ttcacacata tagcaggaaa 1867321 actcgaactt taatcgaaac tgtatgatat agagaatcaa ggaggacgaa acatgaaacc 1867381 gattaatatt caggatcagt ttttgaatca aatccggaaa gaaaatacgt atgtcactgt 1867441 ttttttgctg aacggctttc agttgcgggg ccaggtgaaa ggctttgata actttaccgt 1867501 attgttggaa tcggaaggta agcagcagct tatatataaa catgcgatct caacgtttgc 1867561 gccgcaaaaa aacgtccagc ttgaactcga atagatcaaa aaatgccatg tcaagacatg 1867621 aggaaaggct gtcgggggtt cccggcggcc atttttaaca tgaatccact tttgctccaa 1867681 gctttttgtg taagctgacc atgccaaggc acggtctttt tttatgagaa caacatacgg 1867741 aagtaaaaat ggtatattat gtataaaatg aatttgggag tgatcgatct tgtttgaaag 1867801 tgaagcagaa ctgagacgaa tcaggattgc acttgtatgg atagctgtct ttttactgtt 1867861 cggggcgtgc gggaatcaag ataccattat tgaaacagac aacggcaatt cagactatga 1867921 aacgcctcag cccacctcgt ttccacttga acataaccat tttggcgtta tggaggacgg 1867981 ctatatcaaa atttatgagt ataatgagtc ccgcaatgag gtaaagctga agaaagaata 1868041 cgcggatgat gagcttgaat aaaattcaca agcattcgaa tttacaaagc ggatgccagc 1868101 cgctaaacta aatacagaca cagatcaaac agagggtgaa aacatgaagc ataaagtgat 1868161 cgtgaatcat tgggaagaaa tttgcgaaga tgattcttgc tatgaatacg gaacaagtat 1868221 cattgtgaac ggaaaagaat taatcagaga agcgtcaatt atcactgctt tgaaggcggt 1868281 tttagaagag atcggcgcgg atgttgaaat agaagaaaca gtagagagcg aaaaatgctg 1868341 tgatagctta agaaaaaaaa atctagacta ctaagcagtt ttttttcatg ttatgatata 1868401 catcggctaa aaacgacacc ccgagtagga cgagagatga ttctcgttct gctctctttt 1868461 ttgggcccta atgagtctgc ccgtttgcct gatttgatca aaatatgaat ttttcataaa 1868521 aacgaatcta tatattgtgt ttttgctaga gggtagtata ctatatatag tgttagtgat 1868581 gagagattca tattttttga taggtcgtga taaaacgtgg tacaaatcat atttgattcg 1868641 aaaacaggga atgttcagcg gtttgtgaat aaaacaggct ttcagcagat acgcaaggtg 1868701 gacgaaatgg accacgtgga cactccgttt gttttggtca cctacacgac aaacttcggc 1868761 caggtaccgg catcaacaca atcatttctc gaaaaatacg cccatctctt attgggagtc 1868821 gctgcgagcg gcaacaaagt atggggcgat aactttgcaa aaagcgccga taccatttca 1868881 agacaatatc aggtgccgat cttgcacaaa tttgaactca gcggcacatc taaagacgtt 1868941 gaattgttta ctcaggaggt agaaagagtt gtcacaaaat caagtgccaa aatggatcca 1869001 gttaaataac gaaatcatga tccaaaaaga tgggaaattc cagtttgata aggataaaga 1869061 agctgtacat agctattttg tagattatat caatcaaaac acagtcttct ttcacaattt 1869121 aaaagagaag ctggattatt tggttgaaaa ccaatactac gaagaggaat tcttaagcct 1869181 ttattctttt gaagacatta aagaagtgtt taagacagct tacgctaaga agtttcgttt 1869241 tccttccttc atgagtgcgt ttaaattcta taatgactat gctttgaaaa cgaatgacaa 1869301 gaaaaaaatc ctcgagcgtt atgaggaccg gatctcaatt gttgcgctgt tcttcgctaa 1869361 cggcgacact gagaaagcaa aagaatatgt aaacctgatg atcaatcaag aatatcagcc 1869421 gagcacaccg acatttttga atgccggcag aaaacgccgc ggtgaacttg tgagctgctt 1869481 cttgctcgaa gttaatgatt ctttaaatga catttcaaga gcaatcgata tctccatgca 1869541 gctttctaag cttggtggcg gggtttctct taacctgtcc aagcttcgcg cgaaaggtga 1869601 agccattaaa gatgttgaga atgcgacaaa aggcgttgta ggcgtcatga agcttcttga 1869661 taacgcgttc cgttacgctg accaaatggg acaaagacaa ggctccggcg cggcgtattt 1869721 aaacattttc caccgcgata tcaatgattt tcttgatacg aaaaagattt ctgcggatga 1869781 agatgtgcgt gtcaaaacgc tttcgatcgg tgttgtcatt ccggataagt tcgttgagct 1869841 tgcacgcgag gacaaagcgg cttatgtatt ctacccgcac acgatttata aagagtacgg 1869901 ccagcacatg gatgagatgg acatgaacga aatgtacgac aagtttgtcg acaaccctcg 1869961 ggtgaaaaag gaaaaaatca acccgcggaa actgcttgaa aaattggcga tgcttcgttc 1870021 tgaatcaggc tatccataca tcatgttcca agataacgtc aataaagtgc atgcgaataa 1870081 ccatatttcc aaggtcaaat tttctaacct ttgctctgaa gtgctgcagg catctcaagt 1870141 ttcttcatac acagactatg atgaagaaga tgaaatcggt ctggatattt cctgcaacct 1870201 gggttcgctt aacattctca atgtcatgga gcataaatca atcgaaaaga cagtcaagct 1870261 tgcgacagac tctttaacac acgtgtctga aacaacagac atccgtaatg cgcctgctgt 1870321 aagacgggca aacaaagcga tgaaatcaat cggcctcggt gctatgaacc ttcacggcta 1870381 ccttgcgcaa aacggcattg cgtatgaaag tccggaagcg cgtgactttg caaacacgtt 1870441 ctttatgatg gtgaatttct actccatcca gcgttctgcg gaaatcgcaa aagagaaggg 1870501 cgaaacgttt gatcaatatg aaggatcaac ctatgcgaca ggtgaatact tcgacaaata 1870561 cgtttcaact gatttctcac cgaaatacga aaaaatcgct aatctgtttg aaggtatgca 1870621 tatcccgacg acagaggact ggaaaaagct aaaagcattt gtcgctgaac acggtatgta 1870681 tcacagctac agattatgca ttgcgccgac aggctctatc tcatacgttc aatcaagcac 1870741 ggcgtctgtt atgccgatta tggaacggat tgaagaacga acatacggca actcaaaaac 1870801 gtactaccca atgcctgggc ttgcatctaa taactggttc ttctataaag aagcctacga 1870861 tatggacatg ttcaaggttg tggatatgat cgccactatc cagcagcaca ttgatcaggg 1870921 aatcagcttt acattgttct taaaagacac aatgacgacc cgagatttaa accgaatcga 1870981 tctgtatgca catcatagag gaattaaaac catttactat gcaagaacga aagatactgg 1871041 gcaagacagc tgcctttctt gtgttgtttg attaaaggag agtttatagt gacaaaaatt 1871101 tatgacgcag caaactggtc aaagcatgaa gacgatttta cccaaatgtt ctataaccaa 1871161 aacgtgaaac agttctggct tccggaagag attgctttaa acggcgatct cctcacatgg 1871221 aagtacctcg gaaaaaatga gcaggacact tatatgaagg tactggccgg acttacgctt 1871281 cttgacacag agcaggggaa tacggggatg ccgatcgtgg ctgaacacgt agatggccac 1871341 cagcggaaag cggtgctgaa ctttatggcg atgatggaga acgctgtcca tgcgaagtcg 1871401 tactctaata ttttcatgac ccttgcaccg actgaaacga tcaatgaagt atttgaatgg 1871461 gttaaacaaa ataaatattt gcagaaaaaa gcgcaaatga ttgtcgggct ttacaaagcc 1871521 attcaaaaag atgatgaaat ttcactgttc aaagccatgg ttgcttccgt ctatctggaa 1871581 agcttccttt tctacagcgg tttctattat ccgttatatt tctacggaca aggaaaactg 1871641 atgcaaagcg gtgagatcat taacctgatc cttcgtgacg aagcgattca cggcgtgtat 1871701 gtcggtctcc ttgctcagga aatttataat aaacagacag aagagaaaaa agcagagctt 1871761 cgtgaatttg cgatcgacct cctgaatcag ttatatgaaa atgagcttga gtatacagag 1871821 gacttgtacg atcaagtcgg gctctcacat gatgtaaaga aattcatccg ctataatgcg 1871881 aataaagcgc tgatgaacct tggatttgat ccatacttcg aagaggaaga cattaatccg 1871941 atcgttttaa acggattaaa cacaaaaaca aaatcgcatg acttcttctc tatgaagggg 1872001 aatggctata aaaaagcgac agttgagccg ctcaaagatg atgactttta ttttgaagat 1872061 gaaaaagagc agatataata tctgctcttt tcggcttgaa ggttcaaatg aggaggacgc 1872121 agtacccatg ggaaaaatgg acgaaatgat tttagttgcc ccgcgcgatg atgtgtttaa 1872181 aaaagaaagc ttaaccttcc agggcgtgta cagtgaagat agcagagtag cagaaatcat 1872241 ggctcagatt gaagcggcct atcgtgaaat gagaagaggg gacgcagaag aagatccgcg 1872301 tttcaagcag ccgatacctt atgtcgtcat taagcgtgaa gatgaagttt ttctttacga 1872361 gcggctggct ggcggcggtg aatcacgtct gcacaacaag ctttctctcg gttttggcgg 1872421 ccatatgaac gccatcgaag gggcagcttc atttgctgaa gtcttaaagc tgaacacaga 1872481 ccgtgagctt gaggaagaac tgcaaataaa tgaagaagat aaacaggcga ttgtcacact 1872541 gggattgatc aatgatgatg aaaacagtgt tggcaaagtg catatcggta ttctttctgc 1872601 gcttcaatta aagcctggcg cacaagtgga agtgaaggag aaagaacaaa ttgcgggtaa 1872661 atggatgaaa gtttctgaat taaaacagga tgatatctac aaccgtctgg aaacatggtc 1872721 acagtttgtt gttgatattc ttgaataaaa aaacccggtt tctcgcgatg aggagccggg 1872781 tttttttatg agacgctcgt ccccgtctcg gctatgattc taggatcaca atagcgtcaa 1872841 agccggcatt tttcgctctg gcagcgaggg tgtctgcatt gtctttggat gaaaatgcgc 1872901 caatctgcac tttgtataat ccgtccttta aaaggacaat cgagtcaaaa cctttggctt 1872961 cggcattact tgcgagcgag tcggcattcg ctttgacttt aaatgcgccg atttgaacct 1873021 tatataaccc tgagctggaa gtctttttaa ggttaaaggc ttgctccagc ccgtttgcat 1873081 gtcctctcgc taagctttga ataaaactgc tcgttttcag cttatttgca tcggaaacgg 1873141 tatcaatgaa gccgttctcg gtcaagaggg caggcattgc cgactccctt aggacgtgga 1873201 agttcgctgt ttttttgccg cgatcggcaa agtcgacagc ttgtatcact tcagagtgaa 1873261 ttgtcgattg ataagtcgtc gtcggggctc ctacatctgg ataaatatag ctttcaaaac 1873321 ctgtgcctcc cccggaatta acgtgaatgg acaaaaagaa atctgctccc cagttatttg 1873381 cggcatttgt ccggtcgttt aagctgacat attggtcgct tgtccggctc agcagcagag 1873441 aaacgccttc atattcatta gttaatatcg tacgtaaggc taaagcgatt tgcagggtta 1873501 acgttttctc ctgaaggcca ttacctgttg cgcctggatc agacccgcca tggccaggat 1873561 caataaaaat tttaaccatt tttcatcacc tcattacagg atatgaaaaa acacggcttc 1873621 tgcttgtacg attatcattc aactgaaaaa tgaggaaata accctttcac atccagaaat 1873681 tatttctcgg gaaagcgcac aattcaacat gaagcgacaa cagatacggt ccgacatgaa 1873741 atctgtgcat acgccatatg tttgtatgta ctatgggttc ggttaacctg cactgattcc 1873801 tgctggtttt aagctttgcg ttcatattaa atcaagcatt taaaacgtaa attgatgagg 1873861 aaagctcctt tcattaaaga caccgcttta taaatcgaaa aaaagaaaaa cacttcaggt 1873921 atcttagggc gggtaatacg tttcgtacaa aaatcagccc gttgtatgaa aaagaaataa 1873981 tgagaaagaa gctcactata atactctgac aaaatgatta aaaacaaaat ctcatggttt 1874041 gtccacccca tgtccgtgaa tacaataaga aataaagtat ttctcgggaa agcgcaggat 1874101 tccttattgt tcccgaaaaa agcaattgtt tcgacacatg ataggcgttt gtcacaatcg 1874161 gcatccgctt gaatatcata tagagagaac agagaggtga agatgttgga gcgcgctgtg 1874221 acttataaaa acaacggaca gatcaacatt attctgaacg ggcaaaagca ggtgctgacg 1874281 aatgctgagg cagaggcgga atatcaggct gcattgcaaa aaaacgaagc aaagcacggc 1874341 attttgaagg aaatcgaaaa agagatgagc gcattagttg ggatggagga aatgaaacgc 1874401 aacatcaagg aaatatacgc ctggattttt gtgaaccaaa aacgcgcgga gcaaggcttg 1874461 aaggttggaa agcaagcgct gcacatgatg tttaaaggaa atccgggaac gggaaaaacg 1874521 acggttgcac ggctcatcgg caagctgttc tttgaaatga atgtcctgtc aaaaggccac 1874581 ttaatagaag cggagcgggc tgacctggtc ggggagtata tcggacacac cgcccaaaag 1874641 acgagagatt taatcaaaaa gtcattaggt ggcattttgt ttatagacga agcctactcg 1874701 ctggcaagag gcggcgaaaa ggactttggg aaagaagcga tcgacacact tgtaaagcat 1874761 atggaagaca aacagcatga gtttattttg atactcgccg gatattcacg ggaaatggat 1874821 cattttctct cgttaaatcc cggactccaa tcaagatttc ccatctccat tgattttccg 1874881 gattactctg tgacccagct catggagatt gcgaaacgaa tgatcgatga aagggaatac 1874941 cagctcagtc aagaagcgga atggaaattg aaagattact taatgacagt gaaaagcacg 1875001 acaagtccca ttaaattcag caatggacgt tttgtcagaa atgtgatcga aaaatcgatc 1875061 agagcacaag ccatgaggct tttaatggga gaccaatact taaaaagcga cttgatgacc 1875121 atcaaaagcc aagatctttc cattaaagaa gaagcatctg gatctgcata gacctctcag 1875181 tttttgagag gtctgttttt tgctcgtatt tccgcttttc aaagcaatcg atttgtggta 1875241 tacacatgca gggtttggta tgataatact actgcccaat atgcaaaaga aaggaacatc 1875301 catttgaacg aacaagaaac gattcaggag aaagccattt tagtcggatg tcagctgccg 1875361 catatcacgg atgagcattt tgaaaattct atggaagagc tagcatctct gacgaaaaca 1875421 gcagacggaa aagtactgac cagcgtcaca caaaaacgga acagggctga cgccgctaca 1875481 tatataggaa aagggaaggt agaagagctg aaggcactcg tggaagagct tgaagctgat 1875541 ctcctcatct ttaatgatga actgtcgcca agtcagctga agtcattggc aacagcaatt 1875601 gaagtgaaga tgattgaccg cacgcaattg atattagata tttttgcaaa gcgggcgaga 1875661 acgagagaag gcaaacttca aattgagctg gctcagctgc aatatgcact gccgcgtctg 1875721 acgggacaag ggatcaacct ttcccggcaa ggcggaggaa ttggggcaag aggtcccggg 1875781 gaaacgaaac tggaaaccga ccgccgccat atcagaaatc gcattcatga aatcaacaca 1875841 cagctttcca ctgtcattcg ccatagaagc cgataccgtg aaagaagaaa gaaaaacggt 1875901 gtgcttcaaa ttgcgcttgt cggctataca aacgcaggga aatcaacatg gttcaaccgc 1875961 ctgacgagtg ctgacagcta tgaagaagac ctcctgtttg ccacgctgga cccgatgacc 1876021 agaaaaatgg tcctgccaag cggctacagt gttcttcttt cagatacagt aggatttatt 1876081 caggatcttc cgacgacatt gattgctgca ttccgctcaa cgcttgagga agtaaaagaa 1876141 gcggatttaa ttctgcattt aattgattct tcaaatgagg attatgcggg acatgaaaaa 1876201 acagtgcttc ggctgcttga ggagcttgaa gcagatgata tcccgatgct gacggcttac 1876261 aataaacgtg atcaaaaact gcctgatttt ataccgaccg ccggaaggga tcacattatg 1876321 gtcagtgcga aatttgagga cgacgctgca gcctttaaag aagcgattca gcgctatttg 1876381 cgccaagaac tgttaacgtc ttttgaagca catgtgccgg caagtgaagg gaagctcctt 1876441 tccagaatca aatcggaaac gatggtagac cgcttctatt ttaatgaaga aaatgaacag 1876501 tatgacatat ccggctatgt ccaagaagag caaagtatca tcggtgaatt aaagaagtat 1876561 atgtaggaag gaaatataaa gacatgtttg acacattaac acacggagaa ttattgaaga 1876621 aaacggcaat ggaagtggaa gcggacattg ccggcattca taaacaaata gaagaaatca 1876681 gcgagcgaaa tgagtggaga gtgcttcaaa gctatagaaa acacaaagta agcgacactc 1876741 atttcacgcc gtctactgga tacggctatg atgatatcgg aagagacacg cttgaaagca 1876801 tatatgcgga tgtgtttggc ggagaagcgg ggcttgtaag gccgcaaatc atttcaggca 1876861 cacatgccat ctcaattgct ttgttcggtg tcctcagacc gggggacgag ctcctttata 1876921 tcacgggcaa gccgtatgat acgctagagg aaattgtggg cgtcaggggt ggagaaaacg 1876981 ctggttcgtt aaaggatttt caaatcggct ataatgcggt tgatctgacg aaagacggaa 1877041 agatagacta tgatgcagtc gccgctgcga tcaatccgaa gacaaaagta atcggcattc 1877101 agcgctcaaa aggatatgcg aatcgccctt ctttcttaat tagtgaaata aaagaaatga 1877161 tccgttttgt aaaagaaatc aatgaaaatc tgatcgtctt tgtggacaac tgttacggag 1877221 aatttgtgga agagcttgag ccttgccatg tcggagccga cctgatggcg ggatctctca 1877281 ttaaaaatcc cggcggcggc cttgcgaaaa caggcggcta cctcgtcgga aaagcgaaat 1877341 ggattgaagc ttgctcatac cgtatgacgt cacccggcat cggcagagaa gcgggggcat 1877401 ctctttactc gctccaagaa atgtaccaag gcttcttttt ggcgcctcac gttgtgtctc 1877461 aaagtttaaa gggagcggtg tttacagcga gattccttga aaaactcggc ttcacttcaa 1877521 acccgaaatg ggatgcgaaa agaacggatt taatacaatc cgttgagttt tctgacagag 1877581 aaaagatgat tgctttttgc caggctattc aatttgcatc gccaatcaat gctcatgtga 1877641 cgccttatcc agcctacatg cctggatacg aggatgatgt cattatggca gcagggacgt 1877701 ttattcaagg agcaagcatc gaattatcag ctgatggccc tatccgcccg ccgtatgtag 1877761 cgtatgttca gggaggatta acctattcgc atgtgaagaa tgccatatgc agtgcagtgg 1877821 attcattgat gcaaaagcaa ttaatttaaa ttttttaaaa atttctctgg atttgatgtt 1877881 aagaatcctt acatcgtatt gacacataat ataacatcac ctataatgaa actaagttaa 1877941 gaaaaggagg aaattgagat gagtgataat attcgccgct caatgccttt atttccaata 1878001 ggaattgtca tgcagttaac tgagttatca gcaagacaaa ttcgatatta tgaggaaaat 1878061 ggactgatat ttccagccag aagtgaagga aatagacgat tattttcatt tcatgatgta 1878121 gataaactgt tagaaatcaa gcacctgata gaacaaggtg taaacatggc aggaattaaa 1878181 cagattctgg cgaaagccga agccgagcca gaacaaaaac aaaacgagaa gacgaaaaaa 1878241 ccaatgaaac atgatctgtc cgatgacgaa ctgagacagc tcctgaaaaa cgagctcatg 1878301 caagccggcc gttttcaaag agggaataca ttccgtcaag gcgacatgtc ccgcttcttt 1878361 cattaatccg ttagcaactg ttttgctata tacatttacc ttttaagagg aggaatttta 1878421 ccaaatggca aagtacacta gagaagatat cgaaaaatta gtaaaagaag aaaacgtgaa 1878481 gtatatccgc cttcaattta ctgacattct tggaacaatc aagaatgttg agattcctgt 1878541 aagccagctt ggaaaagcgc ttgataataa agtcatgttt gacggttctt ctattgaggg 1878601 attcgttcgt atcgaagagt cagacatgta cctgtatcca gatctaaata catttgttat 1878661 cttcccatgg acagctgaaa aaggtaaagt agcacgtttc atctgtgata tttacaatcc 1878721 ggatggcaca ccttttgaag gtgacccgcg aaacaactta aaacggattc tgaaagaaat 1878781 ggaagacctc ggcttcagtg attttaacct tgggcctgag cctgaattct tcttattcaa 1878841 attggacgaa aaaggcgagc cgacgcttga actaaacgac aaaggcggat atttcgactt 1878901 agctccaact gatttaggag aaaactgccg ccgcgatatc gtacttgagc ttgaagagat 1878961 gggctttgaa atcgaagcgt ctcaccacga agtagcacct ggtcagcacg aaatcgactt 1879021 taaatatgct ggagcagtcc gctcttgtga tgacatccaa acatttaaac tagttgtcaa 1879081 aacaattgcc cgtaaacacg gcctgcatgc gacatttatg ccaaaaccat tgttcggtgt 1879141 aaacggttca ggtatgcact gcaatctatc actcttcaaa aatggtgtta acgcattctt 1879201 tgacgaaaac gcagatcttc agttaagtga aacagcgaag cacttcattg caggtatcgt 1879261 gaagcacgca acaagcttta cagcagtaac aaacccgaca gtaaactctt acaaacgtct 1879321 tgttcctggc tatgaagcac cttgttatgt agcatggagc gcgcaaaaca gaagcccgct 1879381 tatccgtatc ccggcttctc gcggcatcag cacacgtgtt gaagtacgca gtgtagaccc 1879441 agctgcaaac ccataccttg cacttagcgt attgcttgct gcaggattag acggaatcaa 1879501 aaacaaactg gaagcgccgg ctccaatcga ccgcaacatc tatgtgatga gcaaagaaga 1879561 gcgcatggaa aacggaatcg ttgaccttcc agcaacactt gcggaagcac tagaagaatt 1879621 caaatcaaac gaagtcatgg tcaaagcgct gggcgagcac ctattcgaac acttcatcga 1879681 agcaaaagaa atcgaatggg atatgttccg cacgcaagta catccttggg aacgcgaaca 1879741 gtatatgtct cagtattaat atctcaatcc cttggcacta aaagtgtcag gggatttttt 1879801 atgttaatag gtaataaatt atggagcggc actgctaaaa agcagggtca cttttagtct 1879861 atgtcactaa taattctatg tactaaattt ttaattaggg aaataattcc acgcttaagg 1879921 aagcaatacg cataaataat tcgacaaatt ctgtgataat tccattgttc aatacttcta 1879981 ccagcaataa taagatgagt aaggtagatg tttatcattg acatcataac caaatgaatc 1880041 cataattacg ttgaaatcta aatcaatttt caaaaaggag atttctatga aaaaattgac 1880101 tatcttctcc gggggattag gagcggtttt ttctgtactg gctcaactgt ttgcggttat 1880161 agatgactct tacactttgg ggaatttatg gtttttaggt gctttggcgg gaattataac 1880221 catgcttgct tcaatccaga caaataataa accagtcttc agcatattat taattgctag 1880281 ttcagtaata ggtctacttg gaactggtct tgtatacatc ataccaacac tgttcaatat 1880341 aataataatt tataaatttt caaaagtaag ccaataagcc aatgggaaaa ttaaggttct 1880401 ttttttattt aacatccctt tgacaaggtc ggtgataaat cgcagaatgt ttatgcttgc 1880461 aactaatcca ccagcggggg catcggtggg catgattatc taacgccatg tttctaggat 1880521 accggaattg aaacatttgc tgaggcattt cgtgaagctg atcaccaaat gaccatttcc 1880581 atagaggcac gtctaaagaa gctatcatag gaggacaata ctgtgtggaa agctttaagt 1880641 caattactca agaaacagaa aaatcaaagt ccaagcgatg aagattatat acagattcca 1880701 gaattagaag taaaagtttt ggggatgctt cacagtatca atatagacct ggttaatgta 1880761 atagcccaag cagaaaagtc taaggagttt ataggacaaa tcgaaggcat ctggcattct 1880821 atagcaaatc aattttattc actcgcccaa gggtttgaga atgaggatat caataagctt 1880881 tctgcggatc ttgatcatgc tgccgccact tgggaagctg ttgctaataa agcaaaagag 1880941 tttgtaacaa attcatacca agggtaaaag aaaaataagg gcctgaaagg gctcttttgc 1881001 ttatagtcat atttcccgta agtattactt tttggattta ataaatttta aagcgtgttt 1881061 gtttcactga attcatagtc aaaaggggaa tgtttttatg cttggaatca acgttgaaaa 1881121 atcaaatgaa aacttaatta tcaattggca gctatccaaa attgaaattc caatcaaaga 1881181 aatcaatgat gtatttcttg atccaaacta tgggggagag gagaaaagcg cagtaaggat 1881241 tgggtttcct tatggctcaa cagatagggt agtaattaaa acagcacgta acacttacat 1881301 tttgttcacc actaatcctg ctttaattat gagtaaaatt gtttcttaat aaacagttta 1881361 tgtccctttt aaatttatct attaatgttc tgtgtggtaa aatttagtga gatgatttaa 1881421 ggaggaggag catttatgga agaaataaaa gttagttcac atgacactag atggtattaa 1881481 gaaagcagtt tctaaatatg gtacattccc tatgtttcat catggaggat atgtcatgga 1881541 agatgctact tttcatttca aagatcctgc tagtcctcaa gaaattagcg atatagaaca 1881601 gaagctaggt gttactttcc ctaatgacta taaagagttt ttgttacagc acaatgggat 1881661 ggaaatgttt gatgggattg aaatacttag cttagaggga atcattgaat ataatgaggt 1881721 tcaagatttc ccagagggat acgttttaat tggatatcat tttgatggaa gatatgtcat 1881781 agacacaaac aaatcaaaaa atggattagg ctatatgcta tatctagact caattgatga 1881841 tattgaagat gcgattaact tagattctaa tttcgagata tggtttgata tgctagtgtc 1881901 tttaaatgga acgaaatatt gggaagtaaa tccgaatctc caagagtatt ataaactggt 1881961 ttcagaataa cacttcggca aaagaaaaaa ttatgactaa tttcaacaac caaagaaact 1882021 gcaatttgag ggaagtataa tgacaattta cgagcaaatt aaggatgctt tgaaaaataa 1882081 gatcaatgag ttggtttcac ctcaagaagt aaagaaaacc cttcaagaaa aatacggaac 1882141 taatccggat agcattattt tatcagatta ttgttataac cggtataata aggggatttc 1882201 ttttaataag cacctctttg aatatatgaa tagaagttct tacaaatact taggtgaaaa 1882261 ctctctttat acaggactta ttttcagaaa atcaaaaggg gaagataagg aagttatcgt 1882321 aggcgaatgg gtaaacggtg ttaaatcact ccgagaagct tctgttacta ataaccaaat 1882381 aaatgatcaa gccgaaatca ttagtaaaga acaacttgta aacctttata atgaatataa 1882441 ccaaatcctg agatatgaaa tgaatgtatt gaactgtaag cctacagaat tgaggcattt 1882501 aattggcaga atcggtgaat tcatttgtgc aatccaaacc aacggcactc tggcacgtca 1882561 aactaatcag catggatttg atgttgtgag tgatggcaga cggattagtg taaaaacaac 1882621 agctcaatca agtggtttta tttcgataaa taaaaataca ttttatgatt ttgatgattt 1882681 ttttgtagtt caatacgtaa atgatgattt taaagttatt ttcttcggct caaaggaaga 1882741 agtgcaaaaa ataagcagaa tttatggaag ccaatacgaa gttgaaattt cacttcttaa 1882801 aaagcttaat aaggaatacc aattaaatta aacaatcttg ttggtaacaa acatcctctt 1882861 acttattgta agaggatgtt tgtttaattc ttacatattt tatctttgca atctggctta 1882921 cgagttgcat ccacagtaaa tgatcttact tcgtctttag ttttgtcata aattccccat 1882981 attacccctc agagaaggat agggggatta ttttggagaa tcatattcca ttgcttgttc 1883041 acagtcagta atccttgagt tgttctagca agaggcaata ttgttgaata agaatagttt 1883101 taaagaggtt attgttgtct tcatattgaa ataaagatta agtatattag aggggagttg 1883161 ctttaatgca cataacaaca aaaaggttat tgatacgtga atttgaattc aaagattggc 1883221 aagcagtata tgagtataca tctgatagta atgtaatgaa gtatatacct gaaggggttt 1883281 ttactgaaga agatgcaaag gcatttgtaa ataaaaacaa aggtgataac gctgaaaaat 1883341 tccctgtcat actaagagat gaagactgtc ttataggcca tattgttttt tataagtatt 1883401 ttggtgaaca tacatatgaa attgggtggg tgtttaatcc caattatcaa aataaagggt 1883461 atgcttctga ggcagcccaa gctatcttgg aatatggatt taaagaaatg aacttacata 1883521 ggattatagc tacgtgtcaa cctgagaata ttccctcata ccgagttatg aagaagattg 1883581 gaatgagaag agaaggcttt tttaaaaaat gtattccaaa aggcaatgaa tggtgggatg 1883641 aatattatta cgctatttta gaggaagagt ggaattgaac tttattgagt gcggcaatac 1883701 aaacaaatta tcaccctcta cttagaacat attagttaaa tgaaggtgat atataaagtg 1883761 atatgacagt gattaaatgg gattcaatga gctccggtga attgttttta ggtgagttca 1883821 ctaaggatga tacctgatac gcagccatac cattcgagcg ttaatcattt tataactgat 1883881 cttttcactt ttgcccacgg gggaataaga ccctatttaa gtttgccaga cgattgtttg 1883941 atccgttgtt gatgattgtc aggatttttt gtgaaggaat atctttatat agtggttgat 1884001 tattcccttc tggtaaaaat tgatctatgt tgaattgctt aacatgtcat tgaactcaga 1884061 gaataaagtg aacctgccac agatgttcat tatcttttag ggggttccaa aaagaccgta 1884121 ttcctatcga tcgctcagag tgaaaatggt atactaaagt tacaatcaca ggaaggaatt 1884181 acaatttttt tagatctaca taaaatcatc tgattaaccg aaagtgagaa tgtgtgaatg 1884241 aatttaatag ggtatattga ggaaaggttt caaaacctcg aattaattcc tagcatctat 1884301 aatcaatggg gcacaggaat ccatttttgt cttggggaaa atatctatca actcaaagca 1884361 aatgaagaat tgaatttaaa gatgtttcgg attgtatatg aacaaacctc aatcattttt 1884421 aatgaattat ttgaacaaaa tgatgacata ttccttgtga cgaatatgta taagcacaaa 1884481 aagaaagaga aatgtataag aaaattaaag gtgtatcaac cgtttctaaa atgtaaaaat 1884541 catttgaatc aaattatggt gaagacatat ccctatcctt tcgaaatcaa taaagctgaa 1884601 gaatacgaga tgcaacaatt ttccctgtta tgcaaacctc gagacttacg tgtaactgaa 1884661 ttacttaaag cagccagtaa tgaggatttt ccacaaaaac cgaaattcgg aggttactct 1884721 attgattacc ctgatgtttt ctttgtgaac attacaaaag acattatttt ctttatctat 1884781 gatgaccgcg gatgcgaagt catagctcat gatttcaaac gaatacgtcc actttatgaa 1884841 aaatatcacg actgggtaga agagtataag tgcatgtaat acttttttta aaaacgattt 1884901 atcaggaaag gcagaattag attatgaggg ccttacatac aagatgtaaa cggttattga 1884961 aactaagatg gtattatgtg atgatgagag atctgcattt ttattagtac ttgatgaaag 1885021 attagtggat tttgattctc aaggtggaaa ccatattagt gtttatttag ttactcactt 1885081 tgagttatct gatcaatcgt ataaagatgt attaagcttt aatgatgatc ttttgggtat 1885141 ggagcataac tgttcgtatg caatggatat tctaagcgtt aaagaggaac ttgatttcga 1885201 tttcccattt aatatgcttg caataaaaag ctatgtacaa gaattaataa aaatgttagg 1885261 gattgatatc actctgcctg aaatgaaaga aagagatttt gacaaacttt ctcaaaacta 1885321 aataaaacta ctatttttaa agagaacgga gacttgcttt caatatgaat gttaaaaaag 1885381 ctgcagctgt tttttcaatc actattccaa ttatctcagc catcttaatt attaattttt 1885441 ttacaggatt tatgtcaatt ccatggcaag gaatgccggt gttttttcca ttattacttt 1885501 ctcctatagg aatcatttta gcgttcgttt caataaagac aaataaacgg tgtgctgtat 1885561 atgggattgt cttaaatgca attatgtttc catttccttt tttctggttt atcggagggg 1885621 ctttgttatt tggagtttaa aatccattag gcattacgct tatacattgg tattttcgag 1885681 cttgtcaaaa gaaggaataa aaaaacttca gaattgcttg gctttacttt atgttgaaag 1885741 gggtcgagta aggtggatag gaaaaaggat gaaatacaaa gaaaatatag ggaacaaatg 1885801 agggagaaga aagaacgaga aaaagaagat ggcagttcac atacttttga aattgttgtt 1885861 gtgctagcca ttatcatttt gatgtttttc tttaattcag ttttcaaggc tttttagata 1885921 ttgtacagat gactttcagg atgtttgaaa aaataaccct ttgagatata taccgcatga 1885981 aagtattgaa ggacttatga aaattcaaga gccagttgaa tcttaataat taatcaccaa 1886041 ataatgggga tgtaaaatga agttgtataa tgaatttatc aatatagcta aaacgtttaa 1886101 taaagagtta gacataattc cattattata tggatcttta ggtcttgaaa aggtaactgg 1886161 gttagacttt tccccagaag atattgatct ccttattcct ttaatttttt tagaggaaaa 1886221 gtgggaaaaa ctaaaaaaag tgatggaact gcatggatac aaaatggttg atttacatga 1886281 gcatgaattt aagaaaacta atacaaaaat aggcatttct tacattgagg atttaaaacc 1886341 atttgcagat gtagactata ataacctaga gatttttgaa gatggcggag cgaaatatca 1886401 tttgctaacg attgatgatt acctcaagat ttataaaaag tctttattag atggttatag 1886461 aagaaggaag aagaatcata aagaccaaag taaaattaac atattgaata aattaatacg 1886521 gaattaattt ctgtattccc ttttgtttcc agtctcaatt aaaattttta agattaaaat 1886581 aagtttgaag gaaaaatcat agtgtttaac acagccatta atcctcagac agtcaaatag 1886641 ccatttctac tccggttgaa agcttctcta tttttgcttc ttatttatct ttcctgtatt 1886701 gatatatgta tgtagggttg gacttataac ataaactatt ctggccattc cgttctttca 1886761 attcatgacc gggcttgcca tcagcataaa tctaggctaa cagtctccat acatcctgtg 1886821 atcaccttta tcaaactctt aaatgcaact taccactaac caattcttta tttcgcatag 1886881 atcatctttg tcatgtgttt acacaagaat ctgttttgga ctgagacact gaatataaca 1886941 aaacagtcaa aaatcaatat ttaattcatt ctgtttaaac tttctgaaaa agatgttgaa 1887001 aaagtcgaaa ggattttata atattaagtc aagttagttt gtttgatcaa caaactaatg 1887061 aaatgaactt tcattatcca caagataaga tcttactaat atggatggaa gggggataag 1887121 agggtcgatt taatggagct aaacaatata agaaacgaaa gaatgaggct tttatccttt 1887181 tccaggtata taaggtatga cgaaaaaaga tgaatttttt gcttgctgat caccatattt 1887241 ttttgcactg ttttgaaagc gcttttataa aagtttactg accgtaaatt cgagaaattg 1887301 ttataccgtt tcacactgtt ccatattaaa ggatcgaaaa ggggagaaat catgctcagt 1887361 gaaaatgtaa agaagattag catggttgaa aaagttggat atgcgtctgg agattttgct 1887421 tgtaatttaa tttatgcaac agtgtctacg tatcttttgt tcttctatac agatgttttt 1887481 ggtttatcgg cagcagcagc cggtactatg tttttagtgg ttagaataat cgacgctctc 1887541 gctgatcctt ttatcggaac aatagttgac agaacgaaca gcagatttgg acgctttaga 1887601 ccgtatcttt tattcggagc ttttccattt gtcatactgg caatactctg ttttacaaca 1887661 ccagactttt cggatatggg gaaattaata tatgcctata taacctatgt tggcttgtcg 1887721 cttacataca caacgataaa cgttccatat ggcgcgttaa cttctgcaat gactagaaat 1887781 aatcaagaag ttgttagtat aacttctgtt cgcatgttat ttgcgaatct tgggggactt 1887841 gtcgttgcat tttttgttcc cttactggct gcttatttaa gcgatacttc cggcaacgag 1887901 tctcttggct ggcaactaac catgggtatt ttgggaatga taggcgggtg ccttttaatc 1887961 ttttgtttta aaagcacaaa agagcgggtc actcttcaaa aatccgaaga gaaaattaaa 1888021 tttacggata tatttgagca gtttcgtgtt aatcgtccac ttgttgtatt aagtattttc 1888081 tttattatta tttttggagt gaattccatc agtaattcgg ttggcattta ctacgtaacg 1888141 tataacttag aaagagagga tttggtgaag tggtacggtt tgataggaag tttacccgct 1888201 ttggtcattt taccgtttat tccaaggctt catcaatttt tggggaaaaa gaaattacta 1888261 aactatgcat tattactgaa tattataggc ctcttagctt tactgtttgt tccgccaagt 1888321 aatgtttacc tcatacttgt ctgtcgatta atcgctgctg ctggaagtct cactgccggg 1888381 ggatatatgt gggcgcttat tcctgaaaca attgaatatg gagagtacag gactgggaaa 1888441 agaatgggtg ggctcattta cgctataatc ggatttttct ttaagtttgg tatggcctta 1888501 ggaggagttg ttccgggtct ggttcttgat aagtttggat atgtagcaaa tcaggcacaa 1888561 accccggcgg ccttaatggg gattttaatt acaacaacca ttattcccgt gttcttgctt 1888621 gttctagctt taattgatat taatttctat aacttagatg agaaaaaata taaaaacatg 1888681 gttcgagaat tagagaatag agacaaagtt tatttggatc atattgatga tttcaaggct 1888741 taaaaaagaa aataaactga ggaggagtcc caaatgaaga ttaccaatcc cgtacttaaa 1888801 ggattcaatc ccgatccaag tatttgtaga gcaggagagg attattatat cgctgtatct 1888861 acatttgagt ggtttccggg agtccagata caccactcaa aagatttagt aaattggcac 1888921 ttagttgcac atccattaca gagagtttca caattagaca tgaaaggaaa cccaaattca 1888981 ggtggagttt gggcaccatg tttaagctat agtgatggga agttttggct gatctatacg 1889041 gatgttaagg tagtagatgg cgcatggaaa gattgtcaca attatttagt tacttgtgaa 1889101 acgattaatg gtgattggag tgagccgatt aaattaaata gctcggggtt tgatgcttct 1889161 ttgttccatg atacggatgg aaaaaagtat ttattaaata tgttatggga tcaccgtatt 1889221 gatcggcact catttggagg aattgttata caggaatatt ctgataaaga gcaaaaatta 1889281 atcggtaaac caaaagttat atttgaagga actgatagaa aactgacaga agctccgcat 1889341 ctttatcata tcgggaacta ttattattta ttaactgcag aaggaggaac acggtacgaa 1889401 catgctgcta caattgctcg ttctgcaaat attgaggggc catatgaagt tcatcccgat 1889461 aatccaattt taacgtcatg gcatgaccca ggaaatccat tgcaaaaatg tggtcatgca 1889521 tccattgttc aaacacatac agatgagtgg tatttagctc atttaacggg acgtcctatt 1889581 catcctgacg atgattcaat ttttcagcag agaggatact gtcctttggg cagagaaaca 1889641 gctattcaaa aactttactg gaaagatgaa tggccctatg tagtaggtgg aaaagaagga 1889701 agcttggagg tagatgcacc ttctataccc gaaacaatat ttgaagcaac gtacccggaa 1889761 gttgatgaat ttgaggattc aacattaaat ataaattttc aaactttaag gattccattc 1889821 acgaatgaat taggttcatt gactcaagcg ccaaatcatt tacgattatt cggtcatgaa 1889881 tcattgacct cgacatttac tcaggcattt gtagccagac gctggcaaag tctccatttt 1889941 gaagccgaaa ctgctgttga gttttatccg gaaaattttc aacaagccgc tgggttggtg 1890001 aattactaca atacagagaa ctggacggct cttcaagtca cgcatgatga agaacttggg 1890061 cgcattcttg aattaacaat atgtgacaac ttttcttttt cacagccatt aaataataaa 1890121 attgttattc ctcgtgaagt aaagtatgta tatttaagag taaatattga aaaggacaaa 1890181 tattattatt tctattcttt taacaaagaa gattggcaca aaattgacat tgcactggaa 1890241 tcgaaaaaat tatcagatga ttatatccgt gggggaggat tcttcacagg ggcctttgta 1890301 gggatgcaat gccaagatac cagtggtaat catattccgg ccgactttag atattttcgt 1890361 tataaagaaa aataatttgc acatgaaaaa ggagatttct attttagaac tcctttttca 1890421 tatgagaagg tgccatgtca ctattgcttc agaaatactc ctagaataaa aaaactcatc 1890481 tttaaagatg agctgtccat tccataaaaa attacattgt aatcatgtcc agaaaatgat 1890541 caatcacaat ggaggacatt cctaatgccg gtgcattctg tcctaaggaa gatggcaata 1890601 attcatagct attgcctaat tgggaataaa cccttgatga tacttcactt ctcattgaat 1890661 ttaaaaccat aggatgcgat tcaattatgc tatttcttaa aattacggct tgtgggttga 1890721 aagtatttag aatattggta aggcctattc ctaaatagaa tccaaaattt tgtaatgcat 1890781 ttaaggttcc gatatcattc agatgggcga ggtttatgat atcttgatag gacagttttt 1890841 tctctttggt ctgaagagat tttaataaag ccttctctga agcatacaat tcccagcatc 1890901 ctcggtttcc gcaactgcat ttaggaccat taaagtctat tgtcatatgt cccatttctc 1890961 cagagaagcc gcttactcct ctatataaat gattgttgat aataacaccg atccctattc 1891021 ctgtgctgat acttacgtaa ataatgttat cgtgattttt tgcagctcca aatacttttt 1891081 ctccatatgc gccagcattt gcctcatttt caataaaaac aggcacattg tacttctctt 1891141 gtatcgaaga ttttaagtca atatctctcc agttggagtt cggagtgaaa acaatttttt 1891201 gatctttatc aatgagtcca ggcacgcaaa tacctatacc aataagcccg tacggagatt 1891261 ggggcatttg cgtaataaag tgatgaatca tatcaatcaa aatgtctttc gttatttctg 1891321 gagaattgga ttccaaatgg cggtattgat caagaacgat tgttccttca aggtctgtta 1891381 aaatgccatt aatataatcc acaccaacat ctattccaac ggagtatcct gcctttttat 1891441 taaaaacaag catgacaggt cttcttccgc cacttgattg tccttgacct atttcaaata 1891501 ccatactttc tttcattaac gtgtttacct gtgatgagac agttgattta tttaatccag 1891561 tcatttcaga taattttgct cttgaaatag gtgaattttt aaggatttct tttaataata 1891621 acttttgatt tacttttttg acaaaggttt gatcagcgat atccacttca tccactccat 1891681 ttgtttaatc tttaaattaa gtatcaacat agtacatagc gaatcttccc tttattatat 1891741 ctaatgtgtt cataaaaaac taaaaaaaat attgaaaata ctgacgaggt tatataagat 1891801 gaaaataagt tagtttgttt aaacaacaaa ctaataggtg atgtacttac tatatgaaat 1891861 aaaatgcatc tgtatttgaa tgaatttatt tttaaggggg aaatcacatg gctcaatctc 1891921 attccagttc aatcaactat tttggaagcg caaacaaagt ggtttacgaa gggaaagatt 1891981 cgactaatcc tttagcattt aaatattata atcctcaaga agtaatcggc ggaaaaacgc 1892041 tgaaagagca tttgcgattt tctattgcct attggcatac atttactgct gatggtacag 1892101 acgtttttgg agcagctacg atgcaaagac catgggatca ctataaaggc atggatctag 1892161 cgaagatgag agtagaagca gcatttgaga tgtttgaaaa actagatgca ccattctttg 1892221 cttttcatga ccgggatatt gcaccagaag gcagtacgct aaaagagaca aaccaaaatt 1892281 tagatatgat catgggcatg attaaagatt acatgagaaa tagcggcgtt aagctattat 1892341 ggaatacagc aaacatgttt acgaatcccc gtttcgtcca tggtgccgcg acttcttgca 1892401 atgcagatgt gtttgcgtat gctgcagcac aagtgaaaaa agggttagaa acagcaaaag 1892461 agcttggcgc tgagaactat gtattttggg gcggccgtga aggatatgaa acattgttaa 1892521 ataccgattt aaaatttgag cttgataatt tggctagatt tatgcatatg gcagtggatt 1892581 atgcgaagga aatcgggtac acagggcagt ttttgattga gccaaaacca aaagagccga 1892641 ccacccatca atacgataca gatgcagcaa caaccattgc ctttttgaag caatatggct 1892701 tagacaatca ttttaaatta aatcttgaag ccaatcatgc cacattagcc gggcatacat 1892761 tcgaacatga attacgcatg gcaagagtac atggtctgct tggctctgtt gacgcaaacc 1892821 agggtcatcc tcttttaggc tgggacacgg atgaatttcc gacggattta tattctacga 1892881 cattagcaat gtacgaaatc ctgcaaaatg gcggccttgg aagcggcgga ttaaactttg 1892941 acgcgaaggt cagaagatct tctttcgagc ctgatgatct aatatatgcc catattgcag 1893001 ggatggatgc atttgcaaga ggattgaaag ttgcccacaa attaatcgaa gatcgtgtgt 1893061 ttgaagatgt gattcaacat cgttaccgca gctttactga agggattggt cttgaaatta 1893121 tagaaggaag agctaatttc cacacacttg agcaatatgc gctaaatcat aaatcaatta 1893181 aaaacgaatc tggaagacag gagaaattaa aagcgatatt gaaccaatac attttagaag 1893241 tataacagga taagctccag atcctgctat caataccaag tcactgaatt acccgtcatg 1893301 attcctttcc tattgcttgt tgttatgacg ggtaacttct ataattagga tttatttaga 1893361 gtgaatggtt ttttaaaagg gcaaggagtg aaaaaatgaa gtatgtcatt ggaatagatc 1893421 ttggaacgag tgctgttaaa accattttag ttaaccaaaa cggcaaggtt tgtgcagaaa 1893481 cgtccaaaag gtatccgctc atccaagaga aggcgggata tagtgagcaa aatcctgaag 1893541 actgggttca gcaaacaatt gaagcattgg ctgaattggt ttctatatcc aatgttcaag 1893601 ccaaggatat tgacgggata agctattcgg gacaaatgca tggattagta ctgcttgacc 1893661 aagatcgtca ggtgttacgt aatgcaattc tttggaatga taccagaaca acgcctcaat 1893721 gtataaggat gaccgagaaa tttggcgatc atcttcttga catcacaaaa aaccgtgttt 1893781 tagaagggtt tacattacct aaaatgttat gggtaaagga acatgaacct gaacttttta 1893841 aaaaaactgc tgtgtttttg cttccgaaag actacgtgcg attccgtatg accggtgtca 1893901 ttcacaccga atactccgat gcagcaggaa ctttactttt acatattact cgcaaggagt 1893961 ggagcaatga tatttgcaat caaattggta tttctgcaga tatttgtcct ccgcttgttg 1894021 aatctcatga ttgtgtagga tcgctgcttc cgcacgttgc cgcgaagacc gggctattag 1894081 aaaaaacaaa agtgtacgct gggggagcag ataatgcttg cggcgctatt ggagcaggta 1894141 tcctttcttc cggaaaaaca ttatgcagta ttgggacgtc aggggtcata ctttcctacg 1894201 aagaagaaaa agaaagagac tttaaaggga aagtccactt ttttaatcat ggaaaaaagg 1894261 attcttttta tacgatgggc gtcacgctcg ctgcaggata cagcttggac tggtttaaaa 1894321 gaacgtttgc accaaacgaa tcgtttgagc aattattgca gggggtggaa gctattccga 1894381 taggagccaa tggactgcta tacactcctt atttggttgg tgaaagaacg ccgcatgctg 1894441 attcttctat tcggggaagc ttgatcggaa tggatggagc ccataataga aagcattttt 1894501 tgagggcaat aatggaaggt atcacattct ctttacatga atcaattgag ctattccgcg 1894561 aagcgggaaa atcagttcat actgttgttt ctattggtgg gggagctaaa aatgatacgt 1894621 ggctgcaaat gcaagctgat attttcaata cgagggtaat taagttagaa aatgaacaag 1894681 ggccagctat gggggctgca atgctggctg cctttggaag cggttggttt gaatcacttg 1894741 aagaatgtgc agagcagttc attcgtgagg ctgctgcatt ttatccaaag gcgcaaaatg 1894801 ttcaaaaata taaaacacta tttgatttgt ataagaacat ttacactcac acaaaggatc 1894861 tcaatacagc tttgaagagc tttcgaaaaa actaatgatg ttattgtctg gagatcaacc 1894921 gaagaacaat taatgatcaa tcatcatcaa aggcctttga taacatggct gccttctttt 1894981 gaaaagatgg tgagaataag gtatcgcaac ctttaaacag tattggagta tccagcagac 1895041 aaaacgaacg agtggaaccg tattttgtca gcgaacactt caagaagtgg ggaagcttag 1895101 gaatgccaat gggtaagatg tatgaaaccg cgctaacgac ggtagaggga tctcttgatt 1895161 tatgaagaaa taggaaggat gttaacacac aaataacccc tcacattgac gtgaaggggt 1895221 gttttttatt gttactatac agcggaaatt ttacaggcta gttgcatgat tttagcttgt 1895281 taagcagaat ggaactagac tctccatcat ctctttctca ttctttggaa actgcattct 1895341 gctaggtttg ctgctttttt taacaaacag tgtttttcta tttcacacag ccattaaatc 1895401 ctctgttcgt cacataaccg ctcttactcc aaattgacag tttatctgat tttgcttctt 1895461 gctcatctag tctgaattgg tctatgtatt ttgtgttagg ctcatataca tatgctactc 1895521 tggccaatcc ctctttcaat aatgtctctt gaacagattt gccgtcaaca taaacgtatg 1895581 ctaacagtct tccatactta tctctgcgat cgcctttatc aaattccagc tgtagcttac 1895641 cgctgttgac caattcttta tttcgtttcg acgcatcctc accgtatggt tgaacacaag 1895701 aatttggttt cttcgtctca ggtgtatcaa cgagcaagta gcgaactgtg tctttctttc 1895761 cgttgtaaat aaccttaatc gtatctccat ctattgctct atctaatgta acattgacca 1895821 atttcttctg attttttgaa tgaggcgtgc cagccttttg ttctgtctga ttatattcat 1895881 tagagtgagt atcttgagag acttgctccg tcccattaga atctgaatgg tttttggctg 1895941 cgtgatttga tccgcaagct gccaaagtaa tacttaaaac gattgcgatc atactgatca 1896001 aaatcttctt catattgatt ccctctttat cattttctct tttcgcgatt aaacatcatc 1896061 attataacga tatggacatt ttttgtgaat ggaaaacttc aagggaactt ataacactcc 1896121 aaattgccaa tagttaactt cacaacgaga tgatcaaaac atcaccatca catagcggaa 1896181 ataaataatc ctgaaaataa tattgactga aaatgctttt agaattatga taatatgaga 1896241 aatgacaata atgtgacaaa gacattacta caacataaca actaatagct taggtttatt 1896301 ctattggtta aaaatgtaaa cggttacaaa tccagaggcg aaaatctaag atagagatga 1896361 ctttagtttt gactcaatat ccacactgaa agagcttatt aagtattctt aaaggcaggg 1896421 gaaatggata tgaatgaaca tcgaaatcga aggttgaaat taataatgat ttcagcaact 1896481 tttggagggc ttctctttgg atatgacacc ggagttataa atggagcttt accttttatg 1896541 gcaaggccag atcagcttga tttaacacct gttacagaag ggcttgttac gagtattctt 1896601 ttattaggtg ccgcgtttgg agcgttgtta tgcggaagat tggctgatcg atatggccgc 1896661 cgtaaaatga tccttaatct ttccttttta tttttcctgg catcactggg aacagcgtta 1896721 gcacctaatg ttttcatcat ggcggtcttt cgttttttac tggggctggc tgttggagga 1896781 gcctcggcga tggtgccggc ctttttagca gaaatggcac cgcatgaaaa gagagggcgt 1896841 atggtaaccc aaaatgaact aatgattgtt ggcgggcaat ttttagcata tgtttttaat 1896901 gcgatcctcg gtgtaacaat ggcaaatacg ggacatgttt ggagatacat gctagtcatt 1896961 tgtgctgtac cggctatcat gttatttgcc agtatgctta aggtaccaga aagcccccga 1897021 tggctaatct ccaaaggcaa aaacagtgag gcgctgcgag ttcttaaaca aattcgagaa 1897081 gataaacgtg cagaagctga atgtagagaa attcaagaag cggtagaaaa agatacagca 1897141 ctagaaaagg catcactcaa ggacttttct acaccatggc tgcgccgtct tttatggatt 1897201 ggaatcggtg ttgccatcgt gaatcaaatt acaggtgtga actcgattat gtattatggc 1897261 acacaaatcc ttaaagaatc tggttttggt acaaaagcgg ctttaatcgc taatattgga 1897321 aatgggctga tatcagttat tgcagttata tttgggattt ggctggtcgg aaaagtgaga 1897381 cggcgtccaa tattattgat tggtttggca gggacgacta cagcgctcct attgattgcg 1897441 attttctcaa ttgtgcttga tggatctatg gcacttcctt atgtagtgct ttctttgacc 1897501 gttttatttc ttgcctttat gcaagggtgt gtaggacctg tgacttggct tgtcatagcg 1897561 gaaatattcc ctcaaaggtt aagaggactt ggttctggga taagtgtttt tttcctttgg 1897621 atattaaact ttgtgatcgg ttttgctttc ccgatcttgc ttagctctgt aggtttgtct 1897681 tttacattct ttatatttgt ggctttaggt gtattggcaa tcggttttgt gtacaaattc 1897741 atgccggaaa caaaagggcg tacacttgaa gaattagaag agcattttcg ttctcgacac 1897801 gatcataata ctcctgaaca atcagttatt gaggtataaa tatgttgaaa atctctcttc 1897861 ttataggagg gattttttta gtttcagaaa aaacaaaatc cctctggtag agggattttg 1897921 attcagcatt ttaagatgtt ctacacgtat aatactggag ttgatacttt aaaaatctcg 1897981 ccatctctta tataaaaacg agggatgcgg cggcttaatg tagacacgac ttcatagtta 1898041 atcgtattga gcatttcagc cacttcatca acggaaatct cggctccttt ttgcttaccg 1898101 taaatcacga cttcatctcc ttgtttacct tcaccgtttt ctcctaaact gaccatgatc 1898161 atatccattg ttactcttcc cgccactggc actcgttttc cgcgatgaag aacaaacccg 1898221 cgattggaaa gggcacgaga atagccgtca gcatagccaa tcgggagtgt agcaattact 1898281 tcattaggtt ctgcgatgta tgtagcacca tagctaacgg ttcggggttc tgtccgcatg 1898341 gttttcacat aagcgatgcg tgcctttaaa cttaacgcag gttcaagctt aacgagattt 1898401 agttgtttaa tataggctga aggatataaa ccatataagc cgatacctaa acggatcata 1898461 tcagcgctaa attccggaaa tgcgatagct gcagccgtgt tgcacatatg cacggtgggc 1898521 agctcaatcc cctgtttttt taaaaagctg agaaaactga tgaatttttc atgctgcagc 1898581 tttgtgagtg ttgtgtccgg ttcatcagct gtcgaaaaat gtgtgaaaat ccctgtccat 1898641 ctgaggaatt tacttgcctt taaggctttc actacctcta aaagttcttc ctttgtgcgt 1898701 acacctaatc gtcccatgcc ggtatccacg ttaatatgaa tggccagccg gttagcactc 1898761 gcttcttttt ccaatatctc gtttgcttct ttcatccaat caacctgaaa tgctgataat 1898821 gttatattcc aagctgctga cttctttaca caactaaggg atgtaaaacc aagcacaagg 1898881 ataggtgctg taatcccagc tttacgtaaa acgattcctt cctccacact ggcaacagcg 1898941 agctcactcg ccccgtgttc cagtgcatgg cgtgccactt ctatagaccc gtggccataa 1899001 ccgttcgctt ttacaacagc cataattttg ctcttatgtg gaatatgacg gcggatcgct 1899061 cgcaaattct ttttaacggc atcaagattg acttcgatcc aaacttctcg gcaaagcttt 1899121 atcatcaacg cttccttcct tcttatggat tataaatacc acctattgcc gcaagaataa 1899181 atgttaattg ttggatgatt cgatcttatt ttattcaact ttatttgaaa tcattcaaca 1899241 gcaaatccat gtgatacgag aaggtgccta tcaatgttcg aataatagca agtacgggat 1899301 acatgaggct tgtaagtggg gtgttaatgg atgcggcgac cgaggattac aaaaatgatt 1899361 atttgttttg ggacattttt ttctaagggt agatgataac gagaaatcta atcaggaaat 1899421 acttaccgtt gttatgaaca ttgaagaacc ttttaaatga gaagggctga ggaaattctg 1899481 taaaagataa tcggttgaaa aggcagtcga ttccttgttc cataaaccta acatcagagt 1899541 atataattat actcgtattc acaaaaatcg tttaagtaag gggtatacat gaatagggga 1899601 gttagttttc aaataccgaa tgaatatgga aattttctat ggagaatact gcagccggta 1899661 gaaatagcta attataggtg gcaaacgagt ggggaatctt attttgttgt agaaggagag 1899721 ctcgatgatg aggagctttt tcatgactac gaaattgttg agggggcagt ttttgagcaa 1899781 caattaaaaa cgaatcagta ctataccatt ttcgttgaac tgaaagcatt tccatatgga 1899841 aaaatggtta atcaagtcaa tacatatgaa gagtttgctg acagtgattg cgaacttgtc 1899901 cttttgatag cagataatag ctacgtttcg atttactgta aaaacaaaaa tatcattgaa 1899961 aaactttact tcaatgcttt acagcatgat tttgaagacg ttcaatttat aactgatgaa 1900021 aatgacacaa gaacaagcct tactgtatga tactcaataa aaattaaagg agctagtaca 1900081 tgacaatgca aattaaaatc aagtatctag atgaaacaca aacaagaatc agcaaaattg 1900141 agcagggaga ctggattgat cttcgggcag ctgaagatgt aacaatcaaa aaagatgaat 1900201 ttaagcttgt cccattaggt gttgcaatgg agctgcctga aggttacgaa gcacatgtcg 1900261 tccctcgttc aagtacatat aagaactttg gcgttattca aacaaattca atgggtgtta 1900321 tcgatgagtc atataaggga gacaacgatt tctggttctt tcctgcttat gcattgcgtg 1900381 atactgaaat taagaagggt gatcgtatct gccagtttag aatcatgaag aaaatgccgg 1900441 cggttgaatt ggttgaagtc gagcatttgg gaaacgagga tagaggagga ctcggttcaa 1900501 caggtacgaa gtaaacaaaa taaatccttg gctgtcttca tgctgtgtga ttgatcaatg 1900561 gaggtttcag ccaaggtaca tataaatatt atgtataaaa tgaatatttt aatacgaagg 1900621 atttaattaa aaacaaagtt taaaaaggga agttttgaaa aagtgaaata gtaataacta 1900681 aagtcgataa agaacctaaa gatgtcaaag aaacaatttt tctggtgctt tgcttttttg 1900741 aaggtttact tagctcgtgg ataactgccc cccataaaag catggatgct aaaattataa 1900801 tacttatata cataaagatg ctccttttat tatatttaca gtttttacat ttttatcgat 1900861 tttaccacat ttaggattga gttgtcgatg aaacaagcat ctctataaag aaatactttt 1900921 atctaaattt ttataaatag gggaaggcaa ctaaaaacta gtaatgccac taataataag 1900981 ccaagttaaa tgacttgtgt tcattaataa ttgaatttta cagcagccat gagcacaaaa 1901041 aaatctgagt tcgtcgataa atatcataaa aaagcccccg gtatgtcgcc agggaataaa 1901101 tagacgttta agagatttag tgatgttttt tatatgattc gacaaaatca taataatgat 1901161 catcgtcatc ataatacttt ttttcgtaat gataatcgtg atcatcgtaa tactttttat 1901221 catggtcatc atactttttg tcgtaatcat aatgtttttt atcatgatca taatacttgt 1901281 cgcaatcata atgcttctta tcattgtcgt aatacttttt gtaatatgtt tttttccaag 1901341 tataatactc ttctttatat tttttataat aacccaatta aattcctcct ttatgttatt 1901401 cgaatttaat ttatgaagtt taaatgatat ggtatggtca aatgaaataa gaatagtaaa 1901461 aagaggctgt ttaaaacact ttctgaaaaa caaaacggat agctgtttat gaaaataaga 1901521 gcgagagaga gcactcaatc actgtaaaat aatagtaaag tgtatagaga gattagtata 1901581 cgtaaaaagg gactttctca ttgaagaata tttgaacgtt atggttaaga ttcaagagct 1901641 ctatgatgtg atttttcaca ctgcttttga aggatttaga gttagacatc aaaaacaaac 1901701 agcaaaaccg gctagaaaca gatcatataa ggaatgaacc gctgccaaat atcataaaaa 1901761 agttgttaat gatcaaatga atgaaattag agagaattta ttttaaagaa agcccaattg 1901821 cacatggaca aatgacaatt gatattgagg taaaatacaa tgcattaaat cagaaaaagc 1901881 tattggagga tttaatgtgt ttagacaatt tccaatttgg tatacacaaa cacctgacta 1901941 tttgaatttt tatgtaccgc aatatcaaac catttcgtat aatcctcaac aatgttatca 1902001 acggtgtatg taccaaactg gcggtaacta tgagctatgt gacagactat gttatggaga 1902061 aatacaggtg taaaagaggg ggattaactc ctctttaaac acacagtgag tggaataaga 1902121 tcctcacttt atctgcaagt gcttagtatt tgcgataata ttgcattcgt aataaattat 1902181 gcttagcaac tgaaaatgaa agaaggatat gaatagtcat gacgcaattc gataaacaat 1902241 acaattcaat tataaaggat attatcaata atggaatctc agacgaagag tttgatgtaa 1902301 gaaccaagtg ggactcagat ggaacaccgg cacatactct aagtgtaatc agtaagcaaa 1902361 tgagattcga caactcagag gttccgattt taacgacaaa aaaggttgcc tggaaaacag 1902421 ccattaaaga gttgctctgg atttggcagc tgaaatctaa tgatgttaat gatttaaaca 1902481 tgatgggcgt ccatatttgg gatcagtgga aacaagaaga cggaaccatc ggacatgcat 1902541 atggatttca gctggggaag aaaaacagaa gtctaaatgg agaaaaagtg gatcaggtag 1902601 actatcttct tcatcaattg aagaacaatc catcttcacg cagacacatt acaatgctgt 1902661 ggaatcctga tgaattagac gcaatggcct taacgccatg tgtatacgag acacaatggt 1902721 acgttaaaca tgggaaactc caccttgagg taagagcacg gagcaatgat atggcattgg 1902781 gaaatccatt caatgtattc cagtataatg tgttgcagcg catgattgct caagtgactg 1902841 gttatgagct tggtgaatat atctttaaca ttggggattg ccatgtgtac acacgtcata 1902901 tagacaattt gaaaattcaa atggaaagag aacagtttga agcacctgaa ctatggatca 1902961 atcctgaagt gaaagatttt tatgacttta ccattgatga tttcaagtta atcaactata 1903021 aacatgggga caagctttta tttgaggtag cggtttaatg ctgccttttt attgtgcagt 1903081 gaatagatag caggtatcct aatttcatta agcaatctgg aagatgaata aaaattgaag 1903141 gacaaacacg tataatacat aaaaaagatt aactctacag ttaatctttt ttattcagaa 1903201 gaaaatatcc taactttgaa actaaataca aagtaaaagc aatcattaca gttctagata 1903261 ttacaattcc atgaatagct agatcatatc cagcaggtat caacgcattt gtattacaca 1903321 taaaatatat agatattaga agtgctacaa taactaaaat cattccaaaa agacttgttt 1903381 tttcatattt cataccaatt tccaccctta ttaaagttag gtttaaacaa aagagctgaa 1903441 gaaacgaact atgaccagta tgctccaagg aaaaccgcca gacaatgctg gcggcttttt 1903501 gctgcttcgt ttatttatta acagagatcg taacgttatt tcctgcaact gaaacctttg 1903561 cgaaatcctg tgtatctacc acaggagtga cggctttatt gtcgatagtg atgttgttaa 1903621 aagaggtcga aaaggttgct ttgatcgcat cacgctggct ttcatacgaa acagccgcgg 1903681 tagcaagtgt tttccatttt gaaatcgtgc cgatgttggt tccttgaatt tctgtgataa 1903741 tccgtccggt gtagccgtca ttgttcgttc cccaaagggt catgcgcgta ttgccgctta 1903801 aatttttata gattgtcatt tggactgtgc ttccagggcg gaagccttta ttgtatgtga 1903861 atttgtcttt tccttcgatg tacgtttctt catttttgga cccaaccttc atgaggggct 1903921 tccagacgtt gtattgtttg ctgtactgaa gcccgatatc ggcttcagtt ccgcttgttg 1903981 ccctaaagcc agaataaata tagggagtag agaccgagtc gttgtttttg acagtttcag 1904041 gaagcacgat tttagctgta aaaacggcgc ccgtactgtt caggtagaca cggccgccga 1904101 ttccgttagg cagctcggat gctgcttttg cgacttgagc gtctgccgcg ggtaaacctg 1904161 gtatacctga tgaaagggtt ccgaaaagaa ctgctgttcc tactgcacct gcaatcaata 1904221 cttttttcac caaaattccc ccttttgata gtggtttcgc catttattat accttatttt 1904281 ggaactggat ttacgtatat aaatcgacaa aatatttcat tttgaatgat gtaaggtcga 1904341 aacgcttcgc caatctgaaa gctatatacc tttatcagag gaaagaatga gatcacattc 1904401 gttttaaccg atttgaaatt ttcctcaaaa taaaagtaca aatgcttaaa gaaacgatta 1904461 ttaaaagaat gcccgctatc gtttccaagc ctgtaaaaaa gaggtgacgt ttcatcaatg 1904521 tctgtccttg taaaatgata aaagcacaga taccgactaa gaaaagaaaa caaatactta 1904581 ggattgctaa cgctttacgt gagtatgttt tcatttcatc tttaaaatac agcaatacga 1904641 aaataaagca gataacattg gctattgttc taatcacctc aaagcttttc atgacaactg 1904701 atataaatag acaaagtaaa atgagataaa atacgatgtt tctatacaaa aaacctctcc 1904761 ttttatgtag gatcctcaaa gagtttataa aagtttcttt gtaactgcaa taaattgaat 1904821 gcgctcactt atgaactaac taaactatgt actaaatatt cactattctt tttcagattc 1904881 agtcaccaag gttttcatag aaagggaagc ttcagaaata tacatatagt gcacaaacaa 1904941 aaaagacccg gcaatagccg ggggaaagta aaaacgagga gatgttaatg gcgtttagta 1905001 gtgtttttta tgctttttat actctacaac ataatcatag tcttttttat cgtgatcata 1905061 atatttttta tcatagtcat catatttttt gtcgtaatca cagtcataat cttttttatc 1905121 atattcgtaa tacttcttat aatacgtttt tttgaccgta taatactctt ctttgtattt 1905181 tttgtaataa cccatatata ctcctccttt atttttacta cgctttatta tacggcgagt 1905241 agattttgcg gcttggacag ttaaaatcat agaaggaaaa aagggctgtc caaatgatag 1905301 aaaaagacag atgacacaaa aacaaatcaa aataaagagc cgatttttca tcggcccaaa 1905361 cgatttatcc tacatttgtt tgtcttcttt gttttctgag tcattttttc tgatatcctg 1905421 agtcagtccg cttgttgctt gtttaaattc tgataaggct tttcctgctg cacggccaag 1905481 cgccggcagt ttatcaggcc caaatactaa aaaacccaca aacaaaataa cgagtatttt 1905541 tgtgaagctt aattccatat ccttttcccc ctgattgaag tacaaccttt taaacaaatt 1905601 ataagagata gcagtacaaa tgggaatgca tttattttga acattttaaa accagcacaa 1905661 agacggattc ataaaacggc tgctgctgaa tataatgtcc aatgccacct gcctaagaag 1905721 caggaggcag gctggatcaa ttatgtagct ctgccggaaa tgatacaaac gtagcggcta 1905781 tcattgacat agaggagtgg tgtagctgat gagattcact aaggtagttg gatttttgtc 1905841 tgttttaggg ttggctgcgg tttttccatt aacggcacaa gcagaaaaag ccggaactgc 1905901 gggggctgga gagtgggata agttggggac ttacacatat acttactcaa gtccgacggt 1905961 atactcgacc ggaggagatt ttagagtgtg cctttcagga agcactcctt tttctgtttc 1906021 actgcactta tatgaggatg atcccggtga caatcctgat gattatgtag gggcaaacta 1906081 tttttcaccc ggagaatgcc acacctttgg cagtattgga aaatttgtag atgggagcaa 1906141 taacaaggcc gagttctttg ttaccgatta ctctggtaaa tctaaaactg ttacgtttta 1906201 tgattgatgg actcaaattg tgaagtataa cccttggaaa aaaacaaaaa agagagatac 1906261 ctctctcttt tttattcttc gacagcctta cgaagccgtt catttacaat gccagtccag 1906321 ccgccatcca tcttaccgcg aacgacggag cttttctcgt ttgctttgcc gatcacttca 1906381 ttcggctctt tccagccgct gtgaataagg gtaaaccctg tcttttcccc caagtcttct 1906441 aattgaaagg taacgaccca tccttctgta tcccattcaa aagaaagttc agttggagct 1906501 tgaacagcca aaactttaca aggggacggc ccaaacggcg attgtaagtg aaattcttgt 1906561 ccttctttga gctgaaagtc attgggcata aaccacttgg caatgccttc tgaagtagag 1906621 actgtctccc agactttctg aatgggagcc tccagagtaa tgctttttgt aatatccggt 1906681 aatgcatttt cgttgttttg agccatttcg tttacctctt gacatatgat gttttttcaa 1906741 ttcaatcata taataactaa taagatcatg tccatagcgt gcattattta tgctagagct 1906801 gctgttgaac agcgtgtcag tcgccagtct gatctgtgaa tgggagaatt ctgcatgcgc 1906861 gaaaaagaga gagaggtgta tgttgtcatt tcgttcattc ttgtttgcag ccgcaactgt 1906921 tatgtttgaa ctgggattcc tgttcagcca atttattttg cgatttttgt tttaatagta 1906981 aatgagccat tttctaaaac aggaggtttt ttatgcttgg aaaaatcaaa gcagccattg 1907041 ataatagtcc agggaagccg gccagaattt tagttagtga aaaagcgttt cagcaattag 1907101 aggaagaaat gcgctttgtt tacgtttcca aaccgaaaac gataatgggg attcctgtgg 1907161 aagtttcaga tcaggcagaa agcttcaagc tggaatttta gttttcccag actgctaaaa 1907221 ggctcatttt gtgttaatta tgcaaaatgg tcaggttgat ttctttaaaa gcatgatgaa 1907281 atgttcatca tgctttttta ttgagaaaaa agacgaacat aaaaaatagg tatacgggaa 1907341 aaataatcct attagagaga ggggaactga cagatggata acatgatatc aacacttact 1907401 gactggaatg tgtggtttca agcgttagta gtatttctcg ttccatatgt aatctataaa 1907461 gtgtttactt ggattcatgt ataagaaggt gcaatgatga ggtggcggaa caatcagtac 1907521 aaaacacaga agcagcataa atcagattat tcgacagctg aaaagcagga tcaggatgtg 1907581 ttaaccggta acatcggata cgacttagaa catgtaaaaa gaaaaatagg acataacggg 1907641 gacgttcatt tccgtgagct tgaaatcact caattacatg tgaaagcggc attgatcttt 1907701 gttgaaggac tgtctgatca ggacttgatt aataaaggac tatcagtgtt agtcatgaat 1907761 caacctaatc aggtaagcga tgaaatttct caatccggca aaggtatttt aacttcgaaa 1907821 cagataaaaa atcaaatcgt atcaatcggt gatgtcatag attcagagaa aatcagtgat 1907881 atcgtgttga atgttttcat gggttcgaca gcgcttctca tcgatggaat accgcaggcc 1907941 tttcttctgg gaactgtaaa aaaacaaaat cgaagtatcg aggagccgct ttcagaagcg 1908001 cttgtcagag ggccgcgcac aggctttaca gaagagttga gtacgaatac agctcttttg 1908061 agacagcaag gaaaaaatga tcaattaaca ttgcagagat ttgaagtagg aacacgatta 1908121 aaaaaggatt taattatcgc ttatatgaat gacattgcag atccaaaagt agtcgaggaa 1908181 gtaagaaaaa gagtgagagg gattgagatc gatcatttgc cggagtcagg ctacgttgaa 1908241 cagttaattg aggataatta tttgagcccg ttcccgcaag tacagagtac agaacgtcct 1908301 gatcgcgtca taagcggatt aatggaagga agagtagcta ttctgcttga cggcactccg 1908361 tttgctttga ttgttccagt cactttcagc atgatgcttc aatcgcctga agattattat 1908421 gaacggtggt tcccgagctc gctcatcaga ttgctgaggt tcatcgcagc aatgataacg 1908481 ttattcgcac ccgctttata tatatcattt atttcttttc atcctgggtt aattccgacc 1908541 aagctggcga tttcaatttc cgggacgcgc caaggtgttc cgttcccatc tctgattgaa 1908601 gccttattta tggaagtcgc gattgaaatt ttaagagagg cggggcttcg tttgccaaaa 1908661 ccaattggac ccgcaatagg catagttggc ggattaatca tcggggaagc agctgtgcag 1908721 gcggggattg tcagtccaat catggtcatt gttgttgcgc tcacagcaat ttcttcattt 1908781 gccatcccgc attatagcac aggtatagca cttcggatgc ttcggtttgg cgcgatgttt 1908841 tgtgcggcgg tgtttggatt gtttggagtc attatgtatt atctgctgct aagcagccat 1908901 gtcgtaaagc taaagagctt tggtgtgcca tacgcaagtc cggcagtgcc ctatcactta 1908961 aaagattgga aagactttgt tatcagaatg cctcttttag tcatgaagcg ccggcctaaa 1909021 atgatgaata cagataatac aaaacgggtg aagtgatgaa ctcgacagga tggtgataaa 1909081 gtctcatgtt cagcccaacc agtaaaatca caaccgctca ggcaacgatt atcatcatta 1909141 attatatgct tgctgccgga gttcttacgc tccctcggac agtaacagaa caaacacaat 1909201 ctcctgatgg atggatttca gttttattag gcggggtcct agcggtaata gccgggatga 1909261 ttatagctaa attaagccag cagtatccta aggagacctt ttatgaatac tcccgacata 1909321 ttgtaggaaa atggctcggg catctgatca gtattgtttt tattacttat tttctggcac 1909381 tcggtgcatt tgaagtcaga gtcatgtccg aaatcgtgga tttttttctc ctcgaaggga 1909441 caccttcttg ggccatcatt atgacagttc tttggattgg gctttattca attacacaag 1909501 gcctagatcc gattgcacgg ctttttgaaa tgatttttcc gattacggtc atcatctttt 1909561 taacgatagc cctcatgagt ttaggcatat ttgagatcaa caatttgcgc cctgtattag 1909621 gtgatggaat catgccggtt cttagaggtg taaagacaac gaacctttca tttacatgtt 1909681 cagaaattat gttcatttta gtagcattta tgaaaaagcc gaaaaatgcg gtgaaagcag 1909741 ttgtgatcgg gacaggcgtt gtgaccagtt tttatatgat tacgatgatt atggtcatcg 1909801 gtgcactatc agttgaggga gttgtgacga gaacatggcc ggggcttgac ctgatgagaa 1909861 gttttgaaat acctggttta atatttgaac ggtttgaatc atttctgctt gtgatttgga 1909921 ttatgcagct ttttgccacg tttattatca ctttttatgc agcttccctg ggagtctcac 1909981 aagtttttaa aaagaaaccc ctttcatgta tgtttgggct gcttcctgtt atatatatcc 1910041 tctcttgcat gccgaaaaat gaaaatgacg tctttatatt gggcgatacg gtcagtcata 1910101 tcgctttgta tatatttggc gctttgccga ttttgctgtt agtcatttcg aaatggagga 1910161 aaagaggtga aaagtaaact aaaacgtcaa ttgcctgcta tggtcatagt atgtctgctg 1910221 atgatttgcg taacaggatg ctggagcagt cgggaaatag aagatctggg tctcacattc 1910281 gctatcgcaa ttgataaagg aaaagaaacg aacactgaaa aagagttaaa agaagagggc 1910341 gggagctatc cgaaaaaaga caacattacg ctgacctatc aatttgttaa tgaaaaagcg 1910401 gcaggcgcgg gcacaagcgg gggaggcggt agcggacaag gagcgcaaaa agcgtacatt 1910461 aatataagtg aaacagggga ttcattacag cagatcggaa gtgaggttgc attaagacgg 1910521 gaccgagaag tgtttagccc gcatttaaaa gttgttgtca tgagtgaaga tgtgctgcac 1910581 acatttccta tcgacgaaat gctggatcaa ttttttcgtg ataatgaaat caggctgagc 1910641 tgtcttgttt tatctgctaa aggggaagca agagacgctc tccagctgaa agagaacgga 1910701 gaaattccgg catttcggct gattggatta ggtgaaaatg aacataaagt ttccagaatt 1910761 cttcccccta tgacactcgc gaaactaatt ggaaaactgc attctggcag cagcttttta 1910821 ctgcaaaatg tggttgcggc gaatggagcg gtcaagtatt ccggagcagc tgtaatcaac 1910881 ggaaaatcga aaaaaatgat aggcacctta aatgaatatg aaactgaggg gattacatgg 1910941 attagaggag aagggaaagg cggagttgtc aaaagtcatg ataaaaagag ccaacagacg 1911001 ttagcgtacg atatcaataa aatcaaaagc agaattcagc caatcgtaaa agggaaagat 1911061 atttcattcc atgtcgatat tgaatcagaa ggcgatttgg ttgaaaactg gaacacaaaa 1911121 gaggcgttgg acacccagtt tatagatcgt ctcgaaacga ctattgaaaa cgaggtaaag 1911181 aaaatagttg gtcaggtatt aaaaaaaatt cagcatgatt ataaagcaga tgttgcgggt 1911241 tttgatgaat cttttagact tacatatcct cacttatgga aaagggtgaa aaataactgg 1911301 gatgacacct tcagtaaagc cgacatcaca tacagtgtga acgtcacaat tactcatttc 1911361 ggcacggtta aaactcagta atgaatccca aggaagagaa ggaaacctct cttctctttt 1911421 ttatgcattt attaggataa agatactttt tttggagaga tatacacttt tcaaatcgac 1911481 caatatgcta atataggaat tgcttgaaat agaagggaga aggggctgtg aggcagaaac 1911541 cgatttatgt agaaatcgaa atgaaatctg atctggatac actctgggaa tatacacaaa 1911601 acccatcact gcataaggaa tgggatctcc ggttttcaaa tattacgtat ttgaatagtc 1911661 agccatgcga aaaacagaag tttctttacg aaacaagggt aggctttgga ttaaaggtgt 1911721 caggtacagg agaaaccgtc ggtgttttca acaaatgttc atctgaaagg tcttcttcac 1911781 tggcttttgg ctctgatcat ccattatctc tgattcggca tggaagcggc tactggaagt 1911841 atatacagag agaaaatggg aaaatgacgt ttttaacaca gtaccaatac aaaacagcct 1911901 acggactgct gggaagatgg attgatcgtt tattatttcg gccgctgctt ggctgggcga 1911961 ctgcctggag ctttgatgca ttaaggcttt gggtagagca aaataaacat ccgaagcgct 1912021 tcattcgatc tgctatcatc tatgtgttca tgtgtctgtt tttcagcctg ttttggttct 1912081 atcaaggctt tgcaggtgtt aagacaagca tattgacagg aacagcggag ataggcttag 1912141 ctattttgtg gctgcttcct ttaaaaagaa aatggatcat tcatggtgtc caggcttgta 1912201 tttttgctgg gtttgcttgt ctaggttccg aaatattcat gtgggttcta ttgagtgtgt 1912261 tttccgctgc aagcggcgct cttagcctgc agctccccag tgccaggcgc acaaaacgaa 1912321 agagaaagaa gtgacattgt gagttcgatt tatgaaaaat caattattaa ctatcatttg 1912381 ctgcatccca agctgcagaa acggtaccaa ttagacgggt ctcatacatt cagcgggacg 1912441 ggaacgatgt cagaaataag cggaggctct tttctggtta gaatgctgtt aaagctgggt 1912501 gtttttttca gatgcttctt ttcagaaaga ggcaaagaca ttccatttac aatacaaaat 1912561 agaacttgtc ttttgaaatc gcaacataca ggaatagaat ggaatcgtac atttttcttt 1912621 aaaggcaaaa aacgtttctt tgatgcgtta atgatatatg acgagaaaga aaatagaata 1912681 cttgatttct tcggcaaacc tcatctgctg ctgtctgttt tgacgttcga ggcatctctt 1912741 gacggctctc ttacgatcac atcgggaaag caatggctat tgatatgcgg aaaaagaatc 1912801 ccgctgccga aatggctgac cggtacatcc gaagtttgcg aaacgtttga tgaaaaaaag 1912861 aattgtttca ccattgaagt gcatgtgcaa aatacaattc ttggcactct tttcttttat 1912921 aagggaacgt ttcaggagga agagagagaa tcatgaaacg aaatggcata gtcagtgcgc 1912981 tttgttttat tggatttctt gcagcagaag caccggatat ttcagtggca gaggcactcg 1913041 ttttgttatc cattctattt ttcgtgccgg gaatttttcc ttttgttttt cgtcaatctc 1913101 cggttcgtgc tgctcagttt atggaaaacg ggctaatcca gtgctatcct gtagccgcat 1913161 tctttgcggt gctggctcta gtgacggagg ttgggggttt cgcacttatc tggtggatgt 1913221 acacagtttt taatgcattg tatgcgatcc tccgcctttg ggaaacaaag atacatagaa 1913281 tcgaagagac atcagttttg ttcggtctta tttatttggc gggaggagga ttttggtttt 1913341 ttgcttatgc tgcccatttg cagatcatgc aatttggccc tctcatcatt ttgctgactg 1913401 ctgtccactt tcactattct gcttttctga tcccgatctt caacggttta ctcggcagaa 1913461 ccattagaaa acatcggatg ttgtacagtt ggataacatg ggtgattttg ctttcgcccc 1913521 ttcttatcgc actgggcatc acatattcaa aaacacttga tgtcattgcg gttagcattt 1913581 atatggcggc gatttatctt catgcatttt tggtgttcac ggcagctttt cgcaccaaga 1913641 cggggacatt tcttattcgg ctttcttccg ctgttttaat gataacgatt gctttctcga 1913701 tgatttattc atttggtgtc tttcggcaag aagttacatt gaccatcaat cagatgattt 1913761 ggattcacgg ttttgtcaac gcgtttggtg ttatcttgcc cgctctcata gggtggagaa 1913821 tagaggatgc gaaacctttt gatgcagaca gtgtaaagac attcagccgt atctacggaa 1913881 aaagaaagat tggagaagaa tttttagcta acattcaagc tgaaaataac gctcggtaca 1913941 gcggacttgt ggatgatatg ggcagcctgc gttcaaaaga tttttcacca gaaaaactgg 1914001 cgccgctcat tctttcgttt tatgaacaaa ccatcgaata caatattaaa gcaaaagtaa 1914061 catggagcac gtggtttcgg ccgcttgcaa ttatttacga atggttcagc agaagaatcg 1914121 gccaaataca tctttcgacg aaccctgact ggtataggat gtacagcaag ataaaaggtg 1914181 ttcattcgaa aaaagacgga agggaaagag tacgtgcctg gattagaaca aatgaaaaaa 1914241 acgaaaccat ttttaccgct ctttattcag tgtatcgttc aaatggagag gggtatatga 1914301 atatttcttt accgcttcca ttcagcagca tgacaggtat tttaaaacca tatcatcatc 1914361 aggagaagct ggttttaaca agcaggcgga gaaaaagcag agcgggggat gaggggattt 1914421 atctgcaaac aagagcggga acttgtccgc ttcctttatc tgaaaccttt ctgatagaag 1914481 ctgtacatga caacaaatta accgctgttc atcatatgtg gctgtttgga ataaaatttc 1914541 taactgttca ttacagcatt acacatatta accagcctat tgaaagaacc taacacaaag 1914601 aagaagcttc gtctgccagt tgtaatgaga tgaactgttt taaaattctg caccgcatca 1914661 agacaggaaa ggaagggttt atggtgtttt atatcagttt atttctgatt ctttggctgg 1914721 ctgctgggtt tgcagtggga atgaaacaag tgtatgtcga tcagctgttt gataaagctg 1914781 tgatcgaaag actggaaaaa gaagcgaatg atcatggaca tgctgaccgg atgatcaaac 1914841 agcgcgtcct ttatattgca gcagtgacag taagcgggtt tatttctgtt tattatgaaa 1914901 tgaaaacaat cccgcaaagg cgaaacataa gaaaaattga aaaaaacatc atgaaattaa 1914961 atcaagcaaa aaaacgaaga atgaagagaa aataaaaagt gcacaggcca aagggcaggt 1915021 gcatttttgt tttgtatgga aaatggggga ggtggtgcca gcttactttt cataaattca 1915081 aaaatgagaa gaacagcgcc cgggctaatg gtatataata ttgtgaattt aacaaaaatt 1915141 taacaaggag gacgagagaa ttcgtgctaa agcctcaaag agacctacat tctgttgatt 1915201 tggacttaga ggcggagtag atgaaaccgg ccaaagtatc cctgctccgc cgtttgctcc 1915261 attccttgaa gcatgttgat tgtaacatag ccaaacgttt tccatcaact attaaaattg 1915321 taaaattatt gatgattttt atggtgttta ctccgatttc ttcaatttat gctgaagatg 1915381 tatatcagaa ttttgaggaa ttaaaaaaca atgaagatcc ttctgattat ggcgttgtta 1915441 cgaaagaaac cggaagccct gttcttgttt tagctattca cggaggaggt attgaaggcg 1915501 ggacaagtga agtagcgaga gagctcagca aagagtactc gatgtattta tttgaaggct 1915561 taaaatcggc aggaaactca gtcctgcaca ttacgagcac acactttgat gaacctcggg 1915621 cccttaaaat gacgggaaat catgaatatg tcatttcatt acacgggtac gcagaagaag 1915681 atcagcagat cgaagtcggc ggtacagatc gcgtaagagc ggcagattta gttgagaaat 1915741 tgcagcatgc cggttttcct gctgtattgc tcaatatgga ccatccgcat gcgggcgtta 1915801 gtccgaataa cattgcaaat aaatcaaaaa caggtttaag tattcagata gaaatgagca 1915861 cagggtttcg aaagtctttg ttcggcatct tttctttaaa aagcagagct gttactcaaa 1915921 atgagaggtt ttatgagttt acagaagtga tgttccgttt tctcaaaaat agctactgaa 1915981 aaataggagg cgataagaca gcctcctatt ccttatgctt ctctttcgtt tcgggaaaca 1916041 gctcgtccgc ggcttccgtt tgatactgca acgtgttatc tctcgctgac agttcatttc 1916101 ggaaattttc atcaagcaca tttttcagta aataccgatg aaaaaagtat tcaaaaacag 1916161 taagacaggc agcggaaagg agagccgctc caaatggtga gaaatcgttt cttgtttggg 1916221 ttaaaacaaa tacccaaaga ataacgaatg aaaggccaaa gtcagccaat gaagctgtaa 1916281 tattgtttgt tctgggtaag acgagcatgt caccagaaag ataggaaaca aaacctaaga 1916341 aaagtgcaat aaacatcaca cttaaaaagg atgcgtgata gactctgtcc aaaatcacat 1916401 ataaaagggc gagagtgaaa gcaatctttg aagcaagcgc aatgatatgt ttcatttgac 1916461 cacctaaatt gttatttttt gaagaaaatt cttgggcgta aacaaatgat aaataatgca 1916521 attcaaaacc attcataatg gtcatgttac tattttaaac agtccgtttt tgtttacact 1916581 ggtatttttt tcagctgtat gaaactttct tatgaaaaaa gtcgtatatg tggatgatca 1916641 gctttcaagg ggggaatgat ttgtggagat aaaaggaatc aatcacttgc tattttcagt 1916701 ttcgcatttg gatacatcga ttgattttta tcaaaaagtg tttggtgcaa agcttttggt 1916761 aaagggaaga acaactgcat attttgatat gaacggcatc tggctagcgc ttaatgaaga 1916821 accagacatc ccgagaaatg acattaagct ttcttatacc catattgctt ttacaattga 1916881 agatcatgaa tttgaggaga tgtcagctaa attaaaaaga cttcatgtca atattctgcc 1916941 tggcagagaa cgagatgaac gcgatcgaaa atcaatttat tttaccgacc ctgacggcca 1917001 caaatttgaa tttcataccg gaacccttca agacaggctt cgatattaca aacaagaaaa 1917061 aacgcatatg cacttttatg atgaaacggc cttttgatag cacaaccata tttcatataa 1917121 ggttaaattt aaagaagggt gttggtggag actttatgtt tggggaaggt ttctacccga 1917181 cttgttcaac gatgccatat cttttgaact gcacaagtga ttgggtgaag gtgaaattga 1917241 aatacacatt acattacatt ttatatgaag aaagcgagct gttttatcaa atgttgaact 1917301 aattaaacta tgtactaaat tttcagtata tttcaattgc tttgcccctt aataaatata 1917361 aaaccgcatc cttccacgac ctaaaaaatg aaacgttttt aagaagatgg cgtctaatat 1917421 tctaaatgtt catattttga taaaagtttc ctaaaggaaa gaaaatttct tgacttcaac 1917481 aatcttttgg tggataatta tggtgtaaac atgatgttct ttttcctcct attcgggctc 1917541 gcacccaaaa gtcagggcga gcctgctttt tttgaacaac aaaccccctc tccgtaaagg 1917601 aagagggggt tattttatgc atctgataga tcaatagatt aatggacggt tctgaacacg 1917661 ccaatcactt tccctagaat gctgacattc tgcaaaatga taggttccat cgttgggttc 1917721 tcaggctgca agcgaatgtg ggtatcctct ttatagaatc gttttacagt tgcttcatca 1917781 tcttctgtca tcgcaactac aatttcccca ttgttcgctg tgttttgctg tttaacgatg 1917841 acatagtcct tatcgagaat accagcatct atcatactgt ctcccataat ctccagcata 1917901 aatacatgct cgtctggagg aaccatgcgg tcagggagcg gaaaatattc ttcaatattt 1917961 tctactgctg taataggaga tcccgccgtg actttcccga tgaccggtac attaacgacc 1918021 tggctttgcg gaatgtctac ttcttcatca agaatttcta ttgctcttgg ttttgtcgga 1918081 tctcgtctga tcagcccttt tgtttccaaa cgggccaaat ggccgtggac agtagaactg 1918141 gacgcaagcc cgacagcctc tccgatctct ctcacggaag gcggatatcc ttttgattta 1918201 acctctgctt taataaaacg gaggatatca agttgccttt ttgatagctt cgtcattttt 1918261 cgcacctcaa aacgtcgatt ttaagaagat tatagcatga ttttccttac agtacaaaca 1918321 taggttcgaa aaaacaattg acagaaacgt ttgttcgtat atactgaaat tataaaaatg 1918381 cgaacaaaca ttcctgttgg aggttatgat catgagtaaa gaatctatta tttttgtcgg 1918441 tctgtttaca gtgattttga gcgcggttat ccttatgctg tcatatacaa gcagcggcca 1918501 agagcttaat cagtatgtta aaatagaagt ccagcaaggc gacacactct ggtcaattgc 1918561 tgatcaggta gccgatacaa aaaagataaa caaaaatgat tttattgaat gggtagctga 1918621 taaaaatcaa cttcaaacct ctgatatcca gccgggtgat gagttagtga tcccattgaa 1918681 aaagaagcat caggatgcat atgaattagc aactgtaaga tagagaggaa agagagataa 1918741 aatgaaagca ctcatttatg cccgtgtaag cacaaataaa gaacagcagg aaacgtcatt 1918801 aaagcggcag gaggaggagc ttacggccat tgcagcggag aacggcatgg aagtggtcaa 1918861 agtgatttca gaaaaagcca gcggatatga aatggatcgg gatggtgtat ttgagctgct 1918921 cgatgagatt aagaacgctg atattgatgt cattttggtt caggatgaga caaggctcgg 1918981 acggggaaac gcaaaaatcg cactgcttca ttgtatttat agagaaggtg tgaaagtcta 1919041 tacaacggct catagaggtg aactggagtt atcggaggct gactcaatgg tcttggaaat 1919101 cgtcagcatt gtggaagagt atcagcgaaa gattcacaac atgaaaatca gacggggaat 1919161 gaaacgtgca gtaaaaaacg gttttaaacc gcaaaaaaac ttaaaaaacc aacatgggaa 1919221 cagtggaaaa gaaaaaatag aggtgccaat ctcagagatc gtccgcctga gagcgaataa 1919281 actgacgttt gctgaaatcg cggctaccct aagagggttt ggctatgatg tctctaaagc 1919341 aaccgttcac cggcgttttc aggaatacat agagaatgaa gagactgcag agtgaatcag 1919401 ttgtaaaact ttttttgatc tagtactata tagacaaaat gcaataaagg agtttaacat 1919461 gatttcaaac gcgaaaattg ccagaattaa tgaacttgct gccaaagcta aagctggcgt 1919521 tattacagaa gaagaaaaag ccgaacagca aaagctccgt caagagtact tgaaaggttt 1919581 tcgttcttct atgaagaaca cgttaaaaag tgtgaaaatc attgacccag aaggcaatga 1919641 tgttacacca gaaaagctaa aaagagaaca aagaaataac aaacttcact aatataagag 1919701 gaatacggca atatcgtatt cctcttttgc atatactata atcaaaactc ttatgtgaca 1919761 aaattcaaca agtttctctc aaatttaagc tgaaacagtt gagaaaaagt cgtcagacat 1919821 ttatgatgta agggtacaac acataaggaa ggggattttt atggatacaa ttgaaaagaa 1919881 atcagttgct accattcgca cactgtcaat agacgctatt gaaaaagcaa attctggtca 1919941 cccagggatg ccgatgggag ccgctccaat ggcatacacg ctgtggacaa aatttatgaa 1920001 cgtaagtccg gcaaaccctg gctggtttaa ccgtgaccgt tttgttttat ctgctggaca 1920061 cgggtcagca ctattataca gcatgcttca tttaagcggg tttgatctta gtattgaaga 1920121 tcttaaggga ttccgccagt ggggcagcaa aacaccagga catccggaat tcggacatac 1920181 tgccggtgtt gatgctacaa caggtccgct tggccaagga attgccatgg cagtcggtat 1920241 ggcaattgct gaacgccatt tagcggaaac atacaaccgc gattcattta acgtagtcga 1920301 tcattataca tacagtattt gcggtgatgg tgatttaatg gaaggtattt cttctgaagc 1920361 cgcttcactc gcaggccatc ttcagcttgg ccgtctgatc gtactatacg attctaatga 1920421 catctctctt gatggagacc tcgaccgttc attctctgaa aacgtgaaac agcgttttga 1920481 agcaatgaat tgggaagttc tttatgttga ggatggaaac aatattgaag aattaacagc 1920541 ggctatcgaa aaagcacgcc aaaatgaaaa gaaacctaca ttaattgaag tgaaaacgac 1920601 aatcggattc ggttcaccta accgtgccgg tacatccggt gttcacggtg cgccgcttgg 1920661 taaagaagaa agcaaattaa caaaagaagc ttacgcgtgg acatatgaag aagacttcta 1920721 cgttccgtca gaagtttatg agcatttcgc tgtagctgtt aaagaatcag gtgagaaaaa 1920781 agaacaagaa tggaatgctc aattcgctaa atataaagaa gtttatcctg aacttgctga 1920841 acagcttgaa ctggcaatca aaggagagct tccgaaggac tgggatcaag aggttcctgt 1920901 gtatgaaaaa ggaagcagtt tggcatcccg tgcatcttcc ggtgaagttc tcaacggact 1920961 tgcgaaaaaa attcctttct ttgtcggagg ttctgctgac ctagcgggat cgaacaaaac 1921021 gactattaaa aatgccggtg attttacagc ggttgattac tcaggcaaaa acttctggtt 1921081 tggtgtacgt gaatttgcga tgggtgcggc cttaaacggt atggcgcttc atggcggtct 1921141 tcgtgtattc ggcggaactt tctttgtctt ctctgattac ctgcgtcctg cgattcgcct 1921201 tgcagcgtta atgggccttc ctgtgacata tgtcttcaca catgacagta ttgcggttgg 1921261 tgaagacggt ccgacgcacg agcctgttga acagcttgct tcactccgtg cgatgcctaa 1921321 cctttctttg atccgtccag cagacggcaa tgagacagca gcagcatgga agcttgcagt 1921381 gcaaagcact gaccacccaa cagcgctagt gcttacacgt caaaaccttc ctaccatcga 1921441 tcaaacatct gaagaagcat tggcaggagt agaaaaaggt gcatatgtcg tttctaaatc 1921501 taaaaacgaa acacctgacg ctcttctcat cgcttccgga tcagaggtag gtcttgcaat 1921561 tgaagcgcag gctgaattgg caaaagaaaa tatcgatgtt tctgttgtca gcatgccttc 1921621 aatggaccgt tttgagaaac aatctgatga atacaaaaac gaagtccttc ctgcagatgt 1921681 gaaaaaacgt cttgcaattg aaatgggctc atcatttgga tggggcaaat acacggggct 1921741 tgaaggtgac gttctcggca tagaccgatt cggtgcatct gctcctggtg aaaccatcat 1921801 taacgaatac ggcttctcag ttccgaacgt agtgaatcga gttaaggcat taatcaataa 1921861 gtaagctttt gaaagaggat gagtcaaatc atcctctttt tcttgtttat ccgacaaaaa 1921921 tagtattggc tgtttaacag taatagacaa ttctttcttt tcttcttttg tataatagag 1921981 agcaaatgaa atgctgctgg aaaaggggat gaaaagatgg aacgtcacta ctatacgtac 1922041 ctgatcaaag aggaatttgc caatcactat ttcggccggg aatcggttat gtttgagctg 1922101 tttcaagact atcattggac aagccttgaa aagcagcagt atgaaatgac agagaaacag 1922161 attcaatata ttacacaacc aatcccgatt ttacatatgc atcagcggtt aaaaatgaat 1922221 ttaaacaaga cggattacag gcagctggat tatatttata gaatagcttt gccgaaagca 1922281 aaaggccacg cgacgtttat gatgaaggag cacatgatag aaattgtggc ttcgggagat 1922341 tacgaggcag aaacgatatt ctttgaagtg ttaagaaaag taagcccttg ctttttagca 1922401 atggatttca attcgaagcg ttacggatgg ctaaatccgg tgaaagaaag aaattttgtc 1922461 taaaaccgaa gaaaaagaga tgtaaatgtt gtataatagc ttttggttta gtacacttta 1922521 aactagacaa catgaaggag gaaataaaat gactttatgg gttggcatcc tagtgggcgt 1922581 tgttgcattg ctcataggtg ttgcactcgg gttttttatt gctcgtaaat atatgatgag 1922641 ctacctgaaa aagaatccgc ctattaatga acaaatgtta cgcatgatga tgatgcaaat 1922701 gggaatgaaa ccttctcaaa agaaaatcaa tcaaatgatg aaagccatga ataatcaaac 1922761 gaaataatac gtaaagatta tgatatagag aaacatggtt ataaaataaa aaacccttat 1922821 acgggttttt tattttgcaa tcattcatca cccgctactg ctcgaaggcg ctgcttttga 1922881 tattgtatga gaagatggtc aagctcctga ctgagctcta tcgtaatatg agatgtcatt 1922941 ccgttcgcca tgacaatttg cagcagctct gctctttttt tttcaatttc ttttaataga 1923001 tgctctctaa tcacagggat gtatcctttc atacattaga tcttcaaagt gaatgtttat 1923061 attatatcca tatttatact aattttcaaa tgagaaggag tataatgtct caatgtcaaa 1923121 ttaaattata taagtttttt ctgaaaatag aaatccttca agtgaaagtg ttaaaaaaat 1923181 gaaatgattt tgtcataact tgaaggaatg tcaaatcatg aagggatgat gacatgggag 1923241 acgtgaatta ttttttgaca ttcggagcgg ggtttttatc ctttatttcg ccttgctgcc 1923301 tgccgcttta cccagctttt ttgtcatata ttacaggggt cagcatggac gatgtaaaaa 1923361 ctgaaaagct gctgctgcag aaaagaagct tgtttcatac tttgtgtttt ttgcttggct 1923421 tttcagtcat ttttattgct ttaggctatg gaacatcttt tattggcagc ctgtttaggg 1923481 attatcacga tgcgattcgg caaattggcg cgttgcttat tattttgttc ggtttcatta 1923541 cactcggtgt gttccggcct gaggctatga tgaaagagcg gagaatccat tttaagcata 1923601 aaccaagcgg gtttttaggg tcggtcttaa tcggaatggc atttgcagct ggatggacac 1923661 catgtaccgg tccgatatta gctgctgtta tcacacttgc aggcaccaat ccgggctcag 1923721 cggtgccata catgatgtta tatgtactcg gttttgcggt accgtttctt ttattgtctt 1923781 tttttatcac aaagctgaag tggataagga agaaccagct tttcattatg aaagctggtg 1923841 gcgttttgat gattgtgatt ggtgtgctgt tattctttaa ttggatgagc ctgatcatta 1923901 ttttgctgtc agatcttttt ggaggcttta ctggtttttg acggtaaatt actttcgtac 1923961 tactactaat ccttttgttt ttggtacaat aagactatta tctgtggaaa tcgattgttg 1924021 gaggggaata tgacaagagt tttagttgta gacgacgcca agttcatgag agtgaaaatc 1924081 agagagatct tggaagaggc aaattacata atcgcaggcg aagcggcgga cggtgaacaa 1924141 gcagctgacc tgtataaaaa actgcgcccg gaccttgtga caatggatat tacaatgccg 1924201 gtgaaaaacg gcataaaagc gcttcgtgat atcttaacct ttgatcctaa agcgaaggtc 1924261 atcatgtgca ccgccatgcg ccagcaaaga attgtaacgg aagcaattga gctgggggca 1924321 aaggatttta ttgttaagcc gtttgaggaa acaaaagtgc tggaagctgt aagccgcgtt 1924381 atgggacatt aaagtcattt cttttcaaaa tggttttttt tattgttttg gagtatagta 1924441 tatagtatca acactccgag aaacaaagga atgataagta tgatgattat agtttcatca 1924501 attattgctg tgttaatggc tgtagctgtg atggtggtca gaataaagtc ctctgacaag 1924561 cctgtttcac caaaaaaaat cattcttccg ccgattttta tgagtacggg agcgttaatg 1924621 tttttatttc cggtattttg ggtaactgga gcagagtttt tggaagcatt cactttaggt 1924681 gtgattttct ctatttttct aatcaaaact tctaagttcg aaattaaaaa taatgaaatt 1924741 tacatgaaac gctctaaagc atttgttttt atattagtcg gtcttttggt gatcagaatc 1924801 gtgatgaaat cgatcttgag cacatcaatt gattatggtg cactgagcgg aatgttttgg 1924861 attctggctt tcggtatgat tgtgccttgg agaatcgcca tgtatttatc atatcgaaaa 1924921 cttcataacg agctgcagtc atctaatatt caaatgaatt aaaaaacctt tcctcttgtc 1924981 aggaaaggtt ttttatttga gaagggtctg ataaggttcc aaatcgattt ttttgtcccg 1925041 cagatgcctt tttaagaagg tatggtctct tttaggagtt gcgagaatat agcctttgat 1925101 cataagttgc tgatcaatct ttgctacctt ttcttttaat gcaagctcac cgattttgcc 1925161 tgcgatttta gcttttgctg catctctgaa cagctctggc acgggcgcag tcaattcatc 1925221 tagaaactgt ttgttttcat cgttccataa atgtctgctg ttttcaatat agtaatcctg 1925281 ccaatcaagc tctgatctgc cgtcctcttt tggtaaacgc tttaaaaact ttcgaaacat 1925341 gaaaaaaccg ccgattgata ataagactac catcatgatt acccaaaaca gaataaacca 1925401 taaaaaccat ccttccagca tcaatcattc ccccttattc taaccatatt gtatacgaag 1925461 agagattaga agaacacagt aaaaaaagaa tagaaaaaag tgatagacgt ctagtcaaaa 1925521 gagatagtag atcatattct attgtatagt gaatctgcta tttggccatg ggagagtcac 1925581 tagagggtat ttgacgataa atggacggaa aaaaagtcac tttcataata ggggatgaaa 1925641 gtgacttttt atgtttagct gagaggaaat tgaagagaaa aagaagagcc atcttctgtt 1925701 tctttattga cggcgactgt gagtatttga ttttcgcatt cgacttgaat gtttttgtca 1925761 ttaaaataaa aaggaagcat catttgtttt tcaaaagtct gtcctgacga tttgacagtt 1925821 aagatgaact cgcatccaga aagggtaact gttacttgtg taggctgtaa aaaagtcaga 1925881 tccgcttcta taatatactg ctgacttgtt tcatataaat caataggcaa tgtttcgtcg 1925941 taccaggcga aggggtcttc aaaaaattgc cgaagccatt catccatact atcgaaatca 1926001 ttcgcatcgt tgcgttttga atggttcatg gaagcattcc tccacatatc aaccttgctt 1926061 tacatcatat gcggtggatt ataaatgggt gaacgcataa aaaaacagac actaaggtct 1926121 gcttttctta catatcatgg cttgagttgt gcttttgtct tgtatggttt cggtttttta 1926181 cttttttgct tccgcttaga ggctcgggtt ggccgggatt gtgtccttta ggggcgtttt 1926241 tatgcatatc tttacttgta ttcttattgg tcataaaatg agaacctcct taaaagagtt 1926301 cggtgttatt gattggtttt tctttttttg ttattttggc gttctgcttc agtcagtaca 1926361 agctggtcgt tttcaatata gccggcgcct ttgccttggc tttttgcgtc attcattccg 1926421 ttaatgacgt gattcgcttt tcttttgacc atcattatca cctcaatcat aatatggctt 1926481 cttttattgt gttatatgag agagcgtaaa cagtaaaaat taccggtaca tttttctcat 1926541 aagtcgaact tattgtattt aataaaaaca ttgatattta cttatgtatg attttgtttt 1926601 aatatgaaat tgtgagaaaa ttgtgatgga atgtaatgtt catctgagaa tgatctgatc 1926661 tgaaggggga ttttggagaa tggcaaacga gcaaaaaact gcagcaaaag acgttttcca 1926721 agcgagaaaa acgtttacta caaatgggaa aacatatcat tactactctt taaaagcgtt 1926781 agaagattca ggtataggaa aggtttcgaa gcttccttat tccatcaaag ttcttttaga 1926841 atcagtattg cgtcaagttg acggcttcgt tatcaaaaaa gaacacgtgg aaaatttggc 1926901 aaaatgggga actgccgaat taaaggatat cgacgttccg ttcaaaccgt ctcgtgttat 1926961 tttacaagac ttcacagggg ttccggcagt agtagatctg gcttcactgc gtaaagcaat 1927021 ggcagctgtc ggcggagatc ctgataaaat caaccctgaa attcctgttg atctcgttat 1927081 cgatcactct gtacaggtag ataaagcggg tacagaagat gcattagcag taaatatgga 1927141 cttggaattc gaaagaaatg cagagcgcta caaattttta agctgggcaa agaaagcgtt 1927201 taacaattat caggcagtac cgcctgcaac aggtattgtg caccaggtca accttgagtt 1927261 cttggcaagt gttgtccatg ccattgaaga agacggcgag cttgtaacgt atcctgatac 1927321 gcttgtcgga acagactcac acacaacaat gattaacggt atcggtgttc tcggctgggg 1927381 tgtcggtgga attgaagctg aagcgggaat gcttggacag ccttcttact tcccagttcc 1927441 agaggtaatc ggcgcgaaac ttgtcggcaa gcttccaaac ggaacaacag ctactgactt 1927501 ggcgttaaaa gtaacacaag tgctgcgtga aaaaggcgtt gtcggtaaat ttgttgaatt 1927561 cttcggaccg ggaattgctg aactgccgct tgcagatcgc gcaacaattg cgaatatggc 1927621 tccggaatac ggtgctacat gcggattctt cccagtagat gaagaagcgc ttaactacct 1927681 gcgcctgact ggccgtgatc ctgaacatat tgatgttgtt gaagcatact gcagaagcaa 1927741 tggcttgttc tacactccag atgcggaaga ccctcaattt actgatgtgg ttgaaattga 1927801 cctgtctcaa attgaagcaa acttatcggg tccaaagcgt cctcaggatt tgatcccgct 1927861 atctgctatg caggaaacgt ttaaaaagca attagtcagc cctgcaggta accaaggatt 1927921 cggtttaaat gctgaggaag aaaataaaga aattaagttt aaactcctta acggcgaaga 1927981 aacagttatg aaaacgggtg cgatcgccat tgctgcgatt acaagctgta caaatacatc 1928041 aaacccatac gtgctgatcg gcgccggact ggtagcgaaa aaagcggttg agttagggct 1928101 taaggtgcct aattacgtga aaacgtcact tgcaccgggt tctaaagttg ttacaggata 1928161 tcttgtgaat tcaggccttc ttccatacat gaaagagctt ggctttaacc tcgttgggta 1928221 cggctgtaca acatgtatcg ggaactcagg tccgctttca ccggaaatcg aagaagcggt 1928281 tgcgaaaaat gatcttctga ttacgtctgt cctttccgga aaccgtaact ttgaaggacg 1928341 tattcacccg cttgttaaag gcaactatct tgcttcaccg ccgcttgttg tggcatatgc 1928401 gctggctgga acggtaaaca ttaacttaaa aaccgatcca atcggtgtgg gcaaggatgg 1928461 tcaaaacgta tactttaatg atatttggcc gtcaatggac gaaatcaatg cacttgttaa 1928521 gcaaactgtt acgccagagc tattccgcaa agagtatgaa acagtatttg atgacaacaa 1928581 gcgctggaac gaaattgaaa caacagatga agctttatat aaatgggata acgattcaac 1928641 ttacatccaa aacccaccat tctttgaaga gatgtctgtt gagccaggca aggttgagcc 1928701 attaaaagga ctgcgtgttg tcggtaaatt cggcgattca gtcacaactg accatatttc 1928761 tcctgcgggg gcaatcggaa aagatacgcc tgccggaaag tatttgcaag aaaaaggtgt 1928821 ttcacctcgt gactttaact cctacggctc ccgccgtgga aaccatgaag tcatgatgag 1928881 aggaacattt gccaacattc gcatcaaaaa ccaaatcgca ccgggtacag aaggcggatt 1928941 tacgacgtac tggccgactg gtgaagtaac atccatctat gatgcatgca tgaaatacaa 1929001 agaagataaa accggtcttg tcgtattagc aggaaaagac tatggtatgg gatcttcacg 1929061 tgactgggct gcaaaaggaa caaaccttct cggcatcaga acggtcattg cagagagctt 1929121 cgaaagaatt cacagaagca atcttgtatt catgggtgtg ctgccgcttc agtttaaaca 1929181 aggtgaaaat gcggatacac tcggcttaac gggtaaagaa gtcatcgagg tagatgttga 1929241 tgaaacagtt cgtcctcgtg accttgtgac tgtaagagca atcaatgaag acggcaatgt 1929301 aacaactttt gaagcagtcg tccgctttga tagtgaagtt gaaattgatt actaccgcca 1929361 tggcggcatc cttcaaatgg tgcttcgtga aaaaatgaag cagtcctgat gaatcaatag 1929421 gaagagaagg catttcgctt tctcttcttt ttatgacaca atgtgctgcg gaggtggcat 1929481 atgctgaaaa aatggctcgc agggatcctg cttatcatgc tagtcggtta tacgggatgg 1929541 aatttatatc aaacatacag caaaaaagaa gtcggaattc aagaggggca acaagcacct 1929601 gatttttctt tgaaaacgct atcaggagag aaaagctctt tacaggatgc aaaaggcaaa 1929661 aaagtgctgc tcaatttttg ggcaacttgg tgtaagccgt gccgtcagga aatgcctgcg 1929721 atggaaaagc tgcaaaaaga gtacgccgac aaacttgcgg ttgttgcggt aaatttcact 1929781 tcagctgaga aaagtgagaa acaggtccga gcgtttgctg atacttatga cttaacgttc 1929841 cccattctga ttgataaaaa agggatcaat gctgactata acgtgatgtc atatccaacg 1929901 acatatatct tagatgaaaa aggtgttatc caagacatac atgttggcac catgacaaaa 1929961 aaagaaatgg aacaaaaact ggatcttgat tagattcagt tttttttata ctcaaatatg 1930021 cttacaagtt ttcagaattg gaaaaaataa aagaatatgc ggaggtgaga agcgtgaaga 1930081 agatgagaaa acgttctttt catgagctcg tcatggaaaa caaaaaagag ctgatgacca 1930141 atacagagta tttaaatcag cttgaggaaa agcttgaaca gcgatttaag caaaaataac 1930201 ctttaatttg tattcatgtt tacccctcct tttgagaaac ctatctgttg aggagggata 1930261 aacatgggaa acaacaagaa aaacggtcag cctcaatatg ctccaagcca cttgggtaca 1930321 aagcctgtaa aatataaagc caataaaggg gaaaaaatgc atgatacttc aggacagcgg 1930381 ccgattatca tgcagacaaa aggcgagtag cgaaaattcg agtttatttc taggaggtac 1930441 atccgaatga caaagaacca aaatcaatat cagcagccta atcctgatga tcgttctgac 1930501 aatgtggaaa aattgcagga tatggttcaa aatacaattg aaaatataga agaagcagaa 1930561 gcatcaatgg agtttgcttc aggagaagat aaacagcgta tcaaagaaaa aaatgcaagg 1930621 cgcgaacaga gcattgaagc gtttcgtaat gaaatacagg acgaatctgc agcgagacaa 1930681 aacggatacc gttcttaaaa aaccagggaa acctggtttt tttctttctg atttgattat 1930741 ggtaaaatgg ggctaaattg acgttaaggg agcagagtaa tcttgcatgt atcaaaaaaa 1930801 gaaatagaag tgcgttatgc agaaacagat caaatgggga ttgtctatca cgcaaattat 1930861 cttgtgtgga tggaggtcgg cagaacggcc ttgattaagg acttaggctt tttatatagt 1930921 gatatggaaa aaaaaggcgt tctgtcccca gtcgttgata tcaatatttc ctataaaaag 1930981 ccgcttcatt acggagaaac cgcggttgta catacatgga tagaggacta taacggattt 1931041 aaaaccgtct atggttacca catttataat ccggccggtg agctttccat caaagccacc 1931101 tcatctcata tttgtgtgga taaagaaagc tttaagccaa ttcaattccg caaagctttt 1931161 cctgattggc acacagcata tgaaaaggcc aaaaaatagg gaagtgaacg ggatatggcg 1931221 tttggtgtga aacgggagga acttaaccgg tggaaacaag cagtgaaaag aggagaaatc 1931281 gcatttttaa cacattactg gctggatgac cgatttccag aagcaaagac cgtgacaaaa 1931341 gccggctgtg cagacattga taagctggtt cagtggggag cggcgtacgg gttaaaaaaa 1931401 gaatggatcc ataagaaaag tgaatttccc cactttgatc tgctggggga aacacaaaaa 1931461 tatattttgg aacaagaaaa cctaaccgat catcttatac gatttcattt gtaaaaaaag 1931521 aacgcacatg aagtgcgttc ttttttattg gtattcaaaa accggttcat cagcgtcttc 1931581 tgaatagctg acgagaaggt cgtggttatc aaagtaccat aaatcacttt cttcaataaa 1931641 gaaggtaatg ccatcagctt ctgcagtgac tccagcctct tgtggggcat ctttcgctac 1931701 accgagagaa aaaccctttt gaacgttgct gcagcctcca tagcggacga aaaagcgaac 1931761 ctggtctccg ctttccaaat cgagttcttc tttataccag ttcaatgcgt cttcgttaat 1931821 tgtcatattc ataacagaac acccctttgt tcttcatttg aattttctct attataaacg 1931881 tattaggcta ttctgtgtca aaagagaagt tttttaagct tataaccatt ttactttagg 1931941 ttctgtttta ttgataattc gtttaatgtt cgctcggtgt ctgtatatca caaaaatagt 1932001 gagcagggta acgacaatca ataaatacgt atcatggaca aagaaactat atataacagt 1932061 atagatccct gttaacatcg atgagagaga aacaaattta gtcaagtata aaaagatgaa 1932121 gaataccgca accatcgtga taaataacag gggtgcgtaa aatagcaaaa cgcctcctga 1932181 tgtcgccacg gctttaccgc ctttaaattt ggcgaagatg ggaaacacgt ggcctaaaac 1932241 cgcaaagact cctgcaagaa gcgggtgaat atcaacatgc atgagaaaag gcaatgcagt 1932301 tgccagtgtc cctttcaaaa tatctccggc tatgacgacc gaaccagctt ttacacccaa 1932361 tgtacggaat gcattggtag cgcctaagtt gccgcttccg tgctcccgaa tatcaattcc 1932421 tttggcaagc ttgcccacaa ttaagccaga tggaatgctg cctatcaagt aggccaaaat 1932481 aatcaataaa gcaattaaca tctacatttc tcctttttca aattcccttc tttttatttt 1932541 aacatgagat gtcatgatct gatgataagt ttttttgtaa agtttgctta caaatcaaat 1932601 caaacatgca tcatattttg atttctcctg ttttgatcgt gtaaaataag tgaaaaagga 1932661 gtgacacacg atgcaaaacc cttctaaagc ggaaattaaa gagattcttc aaagaagcaa 1932721 acgtatagcg gtagtagggc tttcagaccg tccggataga acgtcacata tggtttcaaa 1932781 agcaatgcag gacgcgggtt atgaaattat ccctgtgaac cctacaattg atgaggcgct 1932841 aggtgtcaaa gccgtttcat ctttaaaaga gatagacggt ccgattgaca tcgtaaatgt 1932901 attccggcgc tcagaacagc ttcctggagt ggcggaagag tttttagaga cagatgcgcc 1932961 agtattttgg gcacagcaag ggctagttaa tgaggaagca taccagatgc taaaagaaaa 1933021 aggcagaacg gttatcatgg atctgtgcat aaaagtggca cacgctgtaa caaaataggt 1933081 gcagaactgc aaaaatcctt gtaaattcaa ggatttttgc tttttaattt taagatattg 1933141 tttgcgtatt acggtgaaac agatacaata aagcttgaac agcttttttt gaataccttg 1933201 tccagctggg tttcggccgt tcgatttgcg aaggtctgct gctttatata taataaacaa 1933261 acatacgttc tcatagtgta aaaacagcac tagccgatgt tttgagaaga actgattcgt 1933321 tagctctatg ttgcgattgc aaacatattg gttataatga ggagtccaag gcagtactgg 1933381 ctcgaggcga ggtttataaa aaatatctta tatacaaatg atgtgtaaca ctgaaaagag 1933441 aaagacaatg ttagtttttg aaaggggttt gtacgtttgg ctagaaaaca gcaatttgat 1933501 tacaacgaag atgccataca ggtgctcgaa ggccttgagg ctgtcaggaa aaggccgggt 1933561 atgtatattg gctctactga cgcgcggggt ttgcaccact tggtttatga aattgtagat 1933621 aactctgtcg acgaggtgct tgccggccat ggagatcaca taatcgtcaa aatacataaa 1933681 gacaatagta tttctgtaca ggatagaggc cgcggcatgc cgaccggaat gcataagctc 1933741 ggcaaaccaa cccctgaagt gattttaacg gtgcttcatg ccggagggaa attcggccaa 1933801 ggcggctata agacaagcgg cgggctccac ggagttggtg catcagtcgt gaatgcttta 1933861 tctgaatggc tgacggttac cattgagcgg gacggttttg tctatcagca gcgatttgaa 1933921 aatggaggaa aaccggttac atctctcgaa aagatcggca aaacaaaaaa gacgggaact 1933981 cttacacact ttaagccaga tccaacgatg ttcagcacaa ccacttataa ttttgaaacg 1934041 ctctctgagc gcttaagaga gtctgcgttt ttgttaaaag gactgaaaat tgagctgatt 1934101 gatgaacgca atgaccagcg tgaggtcttt tattatgaaa acggcataga agcgtttgtt 1934161 gcttacttaa atgaagaaaa agacgtcttg tctgaagtgg tctcgtttga gggtgagcat 1934221 cattctatag aagtggactt tgcgttccag tttaacgatg gttattctga aaatattttg 1934281 tcgtttgtca acaatgtcag aacaaaagac ggcgggacgc atgagtcagg tgcaaaaact 1934341 gcgatgacgc gtgcttttaa tgaatatgcg cgaaaagtgg ctttgctgaa agaaaaggat 1934401 aagaaccttg aaggcaccga tataagggaa gggctttcag ccattatttc tgtccgcatt 1934461 cctgaggagc ttcttcaatt tgagggacaa acaaaaggaa agctcggtac cagtgaagca 1934521 agatcagcgg tggatgcgat tgtttcagag cagcttgctt actttttaga ggaaaatcgg 1934581 gacaccgcaa cgcttcttgt caaaaaagca atcaaggcga gccaggcgcg cgaagcggca 1934641 cgcaaagccc gtgaagaagc aagaagcggc aaaaaacgaa aaaaatcaga agcgacttta 1934701 agcggaaagc tgacgcctgc gggttcaaga aacccggcaa aaaatgaatt gtatctcgtt 1934761 gagggagatt cagcaggcgg gtcagccaag cagggacgag accgcagatt ccaggcggtt 1934821 ctgcctttac gcggtaaagt cattaataca gaaaaagcta agcttgctga tatctttaaa 1934881 aatgaagaga tcaatacgat cattcatgcg atcggcgggg gagtcggggc agatttctca 1934941 atcgatgaca tcaactacga caaaatcatc attatgaccg atgccgatac tgacggcgcc 1935001 catattcaag tgctgcttct tacctttttc tatcgctata tgaaaccgct cattgagcat 1935061 ggcaaggtgt tcattgcgct gccaccttta tataaggtca gtaaaggaag cgggaaaaag 1935121 gaaatcattg aatatgcatg gtctgatgaa gagatggggg atgtcctgaa aaaagtcggc 1935181 aaaggctata ccattcaacg atataagggt cttggagaga tgaacgcaga ccagctgtgg 1935241 gaaacgacga tgaatccgga gtcccgcaca cttgttaggg tcaaaattga cgatgcggca 1935301 cgtgtagaga gacgtgtgac gacgttaatg ggagacaaag tagagccgcg cagaaagtgg 1935361 attgagaaaa acgtcgcttt cggcttagat gaagaaagca atattttaga aaatgaaaac 1935421 ttatcggtcg ctgaggaggt ttaatgattg tcacagccag aattatttca tgatttacca 1935481 ttagaagagg tgatcggcga ccgttttgga cgctacagta aatatattat tcaagacagg 1935541 gcgctgcccg atgcgagaga cggattaaag ccggtacagc gcagaattct gtatgcaatg 1935601 catacagatg gaaacacgtt tgataaaaac ttcagaaaag cggccaaaac ggtcggtaac 1935661 gtcatcggta actatcatcc gcacggtgac agctcggttt atgaagcaat ggtgcggatg 1935721 agccaggatt ggaaagttcg taatgtgtta atcgaaatgc atggaaacaa tggaagcatc 1935781 gacggagatc ccccggcagc catgcgttat acagaggcac gattatctcc gatagcatct 1935841 gagcttcttc gggatattga caaaaacacg gttgaatttg tgccgaactt cgatgataca 1935901 agcaaggagc ctgtcgtact cccggcgatg tttcctaacc tattggtcaa cggatctacc 1935961 gggatttcag caggatacgc gaccgacatt ccccctcatc atctgggaga agtcattgat 1936021 gctgtcatta agcgtattca aatgccttct tgctctgttg acgaactcat ggaagttatt 1936081 aaagggcctg attttccgac aggcggtatt attcagggcg ttgacgggat aagaaaagct 1936141 tacgaaaccg gaaaaggaaa aatcattatc cgcggaaagg ctgaaattga aacaatcaga 1936201 ggcggacgag aacaaattgt cattactgaa attccatttg aagtaaataa agcaaacctt 1936261 gtaaaaaaaa tggacgagtt ccgtattgat aaaaaggttg aaggcatctc agaggttcgt 1936321 gatgaaacgg atcgaacagg gctgagagtg gtcattgaac tgaaaaaaga agctgatgcc 1936381 aaaggcattt tgaatttctt atataaaaat actgatttgc agatcacata taacttcaat 1936441 atggtggcta tccataaccg ccgtccgatg ctgatgagcc tgccgtctat tttggatgca 1936501 tatatcggac accaaaagga agttgtcaca aaccggtccg tttacgagct tcaaaaagca 1936561 aaagacagac atcatatcgt agaagggctc atgaaagctt tgtctatttt ggatgaagtg 1936621 attgcaacaa tccgttcttc tagcgataaa cgtgacgcta aaaacaattt gatcgcgaaa 1936681 tatgaattta cagagcctca ggctgaagcc atcgtgtcat tgcagctata tcgtttaacc 1936741 aataccgata tcacagcgct taaggaagag gcagaagagc tcggtaaaaa aattgaagag 1936801 ctcgaatcta ttctgagcaa tgataaaaaa ctgctaaaag tgattacaaa cagcttaaaa 1936861 gcactgaaaa agaaatatgc agatacgaga cgctccgtga ttgaagaaaa aattgaagaa 1936921 attaaaatca atctcgaagt catggttgca tctgaggatg tatatgtaac cgttacgaag 1936981 gatggttacc taaaacggac gagccagcgc tcatttgccg cttccaacgg tcaggacttc 1937041 ggaatgaaag atacggacag gatgctgcat cagtttgaaa tgaatacgac agacgtgctg 1937101 ctgctcttta cgaacaaagg aagctacatc tattgtcctg ttcaccagct gcctgatatc 1937161 agatggaagg acatgggcca gcatttttca aatctaatca ctattgaccg tgatgaaacg 1937221 attgtaaagg ctataccgat aaaagaattt gatccgtcgg catatcttct attctttacg 1937281 aaaaacggta tggtgaaaaa gacagagctc actcattata aagcacagcg ttattctaag 1937341 gcacttgtag ccttaaatct gaagggtgaa gatgaactga ttgatgtaca tgtaacaaat 1937401 ggggaaagcc agatctttat ggccactcac ttagggtatg gtctatggtt tggagaagac 1937461 gaagtgaatg tagttggcgc gcgtgcggca ggtgtcaaag ggattaactt aaaagaggat 1937521 gactttgttg tctccggtga gattcttcag caatctgatt caattgtctt gttcacacag 1937581 cggggagcgg ttaaacgcat gagtctttct gagttcgaga agacatcccg tgcaaaacgc 1937641 ggtgtcgtaa tgctaaggga actgaaaaag aatcctcacc gtgttgtagc actgttcgct 1937701 tgcggtcttg aacagcgact aatggcagaa acagaaaaag gcgacagaaa agaactgcag 1937761 acaaaagagt tgcggacaaa cgacagatac agcaatggct ctttcttttt tgatgaagag 1937821 gaatcaggca aggttacagc tgtttggcgc cttcatacag aacaataata aaaaacccgc 1937881 tcatactata tgagcgggtt tcgtttgttt tttatcagct ttcatggttg gtgaatagat 1937941 ctgttacagc atgaatgact tcaatcccct gccatacaaa taaattcagc gctgtgaaag 1938001 aaaataagcc taaaatcacc attcttaaga taaacaacat gtttaacagc ctcctcatat 1938061 tttcgttaca taatcgggtg atgttgaaca tgaagtttgc cgaaataaga cgattgataa 1938121 aatttggcca gtataaagct ttttttccgc tgacgtctgc gggagtatcc cgtacttttg 1938181 ctttcagcgg tcagcagcag aacagccatt gcccataaag cggtcagcgt aaatgcccct 1938241 gtgatggatt tcttctcatc atcagcattt tggccggctt tcatctcatg catttcctgc 1938301 tggtcggcta cggctttata atgatggccg atatcaaagg cgtggggaat tgagaacaaa 1938361 tgaaaactgg caatcgccaa gaataagatg gatgctttca atatcgttac ttttttcaaa 1938421 tgatctcccc ctcctttaat attactgaat atttttataa taatacccca atccatccta 1938481 aaagtaaacc tgatttatta aatttaaaaa taaatttaac tttgttaagt atatatcttt 1938541 ttgcttattt ttgaaagaga aaacttcttt tattagcgta tgtatacccg gtttatggtg 1938601 tgaataaaaa catattttaa atgatatgtt gtttaggatt tattacttta tttatgtgta 1938661 aatcaaagag aaaggcaaga gaatgggaag aaatgattac attgttaata gggtactctt 1938721 tttttaaagc cagtttgcaa ggaatgtttt tattcgtagg aaaataatag agaaggggtc 1938781 gacagagtaa catctggcta tgacaatatt cttctcgaaa aaacttccta attcgtcata 1938841 ttgtgatata ataaaactcg ttatgttaaa aaatctaaca tcaaaatcga attcgtattg 1938901 aattgatgaa aacgggaggt aaatatggag tcttttttca atagtttgat taatattcca 1938961 agtgatttca tctggaaata cctattttat attttaatag ggcttggatt attttttacc 1939021 atacgttttg gttttatcca attccgttat tttattgaaa tgttcagaat agtaggggag 1939081 aagccggaag gaaataaagg tgtttcatct atgcaggcat tctttatttc ggccgcatcc 1939141 cgagtcggca cagggaattt gactggtgta gccttagcaa ttgcgacagg cggaccaggc 1939201 gctgtatttt ggatgtgggt agtggctgca gtaggcatgg cttcaagctt tgtcgaaagt 1939261 acattagcac agctttataa ggtaagagac ggggaggatt tccgcggagg gccggcctac 1939321 tatattcaaa agggtcttgg tgccagatgg cttggcatcg tttttgcaat cttaattacc 1939381 gtctcattcg gcttgatttt taacgctgtt caaacaaata caattgctgg agcattggat 1939441 ggcgcattcc atgtaaataa aatagttgta gccatagttc tggcggtttt aactgcgttt 1939501 atcattttcg gcggtttaaa acgtgttgtc gctgtttcac agctaattgt gccggttatg 1939561 gcaggcattt atattcttat cgctttattt gttgtcatca cgaatattac ggctttccct 1939621 ggcgttatcg ctacaattgt taaaaatgct ttaggttttg aacaagtcgt cggcggcgga 1939681 ataggcggca tcatcgttat cggtgcgcaa cgcggacttt tttcaaacga agcaggaatg 1939741 gggagcgcac caaacgcggc tgcgacggct catgtatccc atccggcaaa gcaaggcttt 1939801 attcaaacat taggcgtatt tttcgataca tttatcatat gtacgtccac agcatttatt 1939861 attttgctgt acagtgtaac gccaaaaggc gacggcatcc aagtcacaca ggctgctctt 1939921 aaccatcaca ttggaggctg ggcgccgact ttcatcgcag tcgcaatgtt cttgtttgca 1939981 ttcagttcag ttgtcggcaa ctattattat ggcgagacaa acattgaatt tattaaaaca 1940041 agcaaaacat ggctgaacat ttaccgtatc gctgttattg ctatggttgt gtatggatct 1940101 ttatcaggct tccaaatcgt ttgggatatg gcggacctct ttatgggtat catggcgctg 1940161 atcaacttaa ttgtgattgc gctgctgtca aacgttgctt acaaagtgta taaagattac 1940221 gcgaaacagc gtaagcaagg acttgatcct gtgtttaaag cgaaaaacat cccagggctg 1940281 aaaaacgctg aaacatggga agatgagaaa caagaagcat aatataaata taaaacaaag 1940341 ctgcattcaa tagttgaatg cagctttttc attattggaa ataaatttaa tttttcgact 1940401 cgaatgaaaa atgacgtgta aagtcccaat tcagtccagt tttctttgtt ctatatgtgt 1940461 catgtgtgtc ttattcattg gaggtagagc aaattgacag gcttttaaac ctccccaaaa 1940521 caagaaatta ggttgataga caatcatgag aaagattttt acaatgagtt cgtgctcata 1940581 agaagtgtag agccaaaatg atgcgaagga ggaaaagatc agatatgaaa cggtcaatct 1940641 ctatttttat tacgtgttta ttgattacgt tattgacaat gggcggcatg atagcttcgc 1940701 cggcatcagc agcagggaca aaaacgccag tagccaagaa tggccagctt agcataaaag 1940761 gtacacagct cgttaaccga gacggtaaag cggtacagct gaaggggatc agttcacacg 1940821 gattgcaatg gtatggagaa tatgtcaata aagacagctt aaaatggctg agagatgatt 1940881 ggggtatcac cgttttccgt gcagcgatgt atacggcaga tggcggttat attgacaacc 1940941 cgtccgtgaa aaataaagta aaagaagcgg ttgaagcggc aaaagagctt gggatatatg 1941001 tcatcattga ctggcatatc ttaaatgacg gtaatccaaa ccaaaataaa gagaaggcaa 1941061 aagaattctt caaggaaatg tcaagccttt acggaaacac gccaaacgtc atttatgaaa 1941121 ttgcaaacga accaaacggt gatgtgaact ggaagcgtga tattaaacca tatgcggaag 1941181 aagtgatttc agttatccgc aaaaatgatc cagacaacat catcattgtc ggaaccggta 1941241 catggagcca ggatgtgaat gatgctgccg atgaccagct aaaagatgca aacgttatgt 1941301 acgcacttca tttttatgcc ggcacacacg gccaattttt acgggataaa gcaaactatg 1941361 cactcagcaa aggagcacct atttttgtga cagagtgggg aacaagcgac gcgtctggca 1941421 atggcggtgt attccttgat caatcgaggg aatggctgaa atatctcgac agcaagacca 1941481 ttagctgggt gaactggaat ctttctgata agcaggaatc atcctcagct ttaaagccgg 1941541 gggcatctaa aacaggcggc tggcggttgt cagatttatc tgcttcagga acattcgtta 1941601 gagaaaacat tctcggcacc aaagattcga cgaaggacat tcctgaaacg ccatcaaaag 1941661 ataaacccac acaggaaaat ggtatttctg tacagtacag agcaggggat gggagtatga 1941721 acagcaacca aatccgtccg cagcttcaaa taaaaaataa cggcaatacc acggttgatt 1941781 taaaagatgt cactgcccgt tactggtata aagcgaaaaa caaaggccaa aactttgact 1941841 gtgactacgc gcagattgga tgcggcaatg tgacacacaa gtttgtgacg ttgcataaac 1941901 caaagcaagg tgcagatacc tatctggaac ttggatttaa aaacggaacg ttggcaccgg 1941961 gagcaagcac agggaatatt cagctccgtc ttcacaatga tgactggagc aattatgcac 1942021 aaagcggcga ttattccttt ttcaaatcaa atacgtttaa aacaacgaaa aaaatcacat 1942081 tatatgatca aggaaaactg atttggggaa cagaaccaaa ttagttaagc ttttttttgg 1942141 cggacatcag taacgatgtc cgtttttatc atctaatagg aggtttgcgt tgtggatgaa 1942201 atactgaaac agtatatggt gctgtataaa aaaatgagta atatgataaa tggtcccgac 1942261 tatccaggta aggaaaaaga catccagcat caaaaagatc agatcgaagt ttacgaaaaa 1942321 cagctgcagc aaggattttc tacagattat gactatgatg tgtttgctga ttctgttatc 1942381 aaatgcgcat atggcgatat gacgctggaa gatttagaag ccgtttatta tggattgaca 1942441 acaccatttt tttgatttgt cattcagcag taaaatttca atttctgtct cactaactta 1942501 agtatacttt gatattgaga cagaaattta tttattttgt ttacttccta gaatatatat 1942561 tatgtaaact agaaaagatg aagaataaag ctttgctgtt tttatgtaca tcctttcttc 1942621 ttcctgtaat tcagcaacaa aataaaaaag cgatttccca atcggaaaat cgccaattca 1942681 gacactctat tatttatgtg tgtctttgtg ctcttaacga tttacaacaa atgttgtcac 1942741 gctttgagct ggaagatgag cccaaaaatg attgcctgat acagtgagat tcgttccagg 1942801 ttgtagattg ctgctgctgc tcgtgatcca tctagatacg tttgaagcag atccattctg 1942861 caaaacaaag ttttggttga ctcctgtgtt gcttttattg atggcaacaa taacgacctt 1942921 gttgtcacct ttataggctg acacgtaaac gttcgcatta gggtttttcg ttgcatcaat 1942981 ccttacatag ccgggacgca caaactttga gaaatgagcc atattgtagc cgcgtttgct 1943041 gatcgtacca tcttctttca taggtccata tgatcttcgg atgtaccacc atacataagc 1943101 ttgaaagtcc ccctctacca tcgcattgtg aatatgctgt gaaacatcca atgcctcagg 1943161 ccatcgatcc gccgagttgg tatcactgtt tggatagtat acttccgtca tccaaaggtc 1943221 cttccccgct cctttttgtt tgaaaagagg ataagggaat tggctgacct gggtgccgta 1943281 caggtgagtt ccgagaatat ccatattggc aagagcctgc ggatcgttca agatcgggtc 1943341 cgacaaattc ttcaagtatt gaaatgactc aggcgcaatg acgcgggcat tgatcgagcc 1943401 ggcgttttct ctcataaagc gaagtatttc ttgcggcgtc caccacgtcc actcgtgagc 1943461 gtaatcaggc tcgttttgga ccgaaatcgc gtaaagattc acaccattat tcttcatgaa 1943521 ggtaacaaaa tcgttaagat gctgcgcgta tgctgcgtac ttgttgtatt tcagccgttt 1943581 agccgatgtg tcaccattcc gattaaaggt ctcaaccata tcacttggag gattccaagg 1943641 agaagcaaaa acgattgctc cgtgtttgac cgcactcttt gcagtctcca cctctttata 1943701 ccaattattt cgattttcat ctacatgaat tcttaagatt gaaaatccta actggttctg 1943761 tccattgcca aaagcagttt ctctttgagc tgctgtaaga tccccagccc aagccggatg 1943821 attcatccct ccaaaaccgc gaatcacttg tttctctgca gatacattaa ctgttacatc 1943881 acttgctgcc aaaacttcag tagcgcctgg ccctaacatg actgacagca tagtgaaaca 1943941 tactaatagt acacaaattg ttttttttat gcgtggaatc atttattcct ctccttcgtc 1944001 atgtgtcttt tacggtatta aaaaatctgc atggcatatc cataatggcg ggctgttccg 1944061 gtgctggccc gtacttcacc cgcctcgttt ttaagcggtc ccattacgag tactatcttt 1944121 gcgtaaactg ccagtaatca aaattaaaca agtttcctgt acctgttccg gtaaatacaa 1944181 agaatacttt gtgcacaccg gttgccccgc ttaccgcagt ttctatttcc ctccacgttt 1944241 gcgctccgcc tgttgaaggc acattcagag ttccaacaag cttaccgtct gcactgtcga 1944301 ggcgcacttc tattttcccg cctaaagtgg atgctacatt tgctttaaat gacctggcac 1944361 cgcccgctcc gaagtctgca tttcctacag caatccagtc tccattttga atgcttgtta 1944421 catgctgatt atttactggc ccgccgggtg ctgtggactt ctctgtcaaa atgcgtccat 1944481 tccaagcaaa cgtttcagct tctacccggt tatatgggtt taaattggaa atttgtgtta 1944541 cacctgcata atttgccgct acctcttgaa tagatccatc tgcattatgc accagcttat 1944601 taatatgggg agagcggtat cctttgccgg ccccgaacag agcggaactg acagtttgcg 1944661 catggtacac cacataccac tcgtttttaa aattgaaaac agcatgatgg ttgtttccgc 1944721 cacctccgaa aaatgcaccc ggatttttca ggaagtgccc tctatatgta aagggaccca 1944781 tgggacttga actggtcatg tagccgatct cacccggggg tttatcggcc gggtgcgtgc 1944841 cgccgaaatt gatgcaatag gagtaataat atgttccgtt atacttgtgc aatcccgaat 1944901 cttcaaacat gaaaggcgca tcaattgtag atgcacttcc aacaacactc gtcatatcag 1944961 gccccaattt tatgactcta gccgttttag gattggccca ttgtccctgc gttggatttg 1945021 aaacgccagg aacgcctccg ccggcataca ggtaaccggt tccgtcgtca tctacaaata 1945081 ctgccggatc aaaaagccat acaacaccag acattcctgg cgtacttggc gttacgagcg 1945141 gttttccgat tgggtcggtc catggaccaa tcgggctgtc tgcggtgaga accccgatac 1945201 ctccgccgct gtttgcgaaa taaaggaaga atttatcctt gccattaatt tttttaactg 1945261 cgattgacgg tgcccatgac gcacctgccc attttgcaat tccacggcct ccattagctc 1945321 cattggcacc tgctaccgga atggctccgt ggtctgtcca gttcaccata tccgctgaag 1945381 atatgacgaa tactctattc aaattggcaa atgaattatc tttaattgtt ccgttgctat 1945441 tatattcata gtcatcactt gacatataga tgtagactct tccgttatag gtcagcgcaa 1945501 ccggatccgc tcccaaatga tggtcgataa gcggatttga attccctata tgttttgcaa 1945561 ttgtagtact agtggcagca tacgcagact tcccagataa gcagctcaat aataaaacta 1945621 gaatccataa acatacgcta cactttttcc tcatcacttc acatcctcct ttttccttaa 1945681 aatgggggat tttcttttgg aatttgataa caacaggtca cgaagattgc acgcataaag 1945741 tagccggaag ctgtttagca atgttcccag ttgttctgaa agctcatctt catgtgtctc 1945801 cattctctct tttcttcgag gagatcgcac cactccttca aaattgttca aaaaaacttc 1945861 cccattccta gcgaccattg tccagaaaat aaaaagacag gattgttcat ggcctcccac 1945921 taatcacatt gaacggagat tacatcatta tccaagatat ccctttatct aacatcctac 1945981 atcattaaaa aaattgtgta tagaaacttt tggaggagtt agtgttcgat tctacaaagg 1946041 aactggatac atttattcat tgataagatg gggctaacac tccgtttata tttgtatgtt 1946101 ttcagacaca aaaaacagcc gttcaatgcg gctgtttttt tcaagagtat aagactattg 1946161 agcggtatac ccgctttttc atgttttgtt catattttat taattgttta ttcaacactg 1946221 tccgctatag taatccatat caacaaatat gactgccact cgcatctttt atgaagggag 1946281 gttcgttacg ctgaaagaaa aaataaagac attaggccgt ttttgcaccg taggcgtcgg 1946341 caatacgctg atagattttg gtgtcttctt tcttcttacc gcttgtcatg tctcttatct 1946401 gccggcgcag atctgctcct atactgcagg tatcgtcaac agctatgtgt ggaaccggaa 1946461 ttggacgttt tgtgtgaaac gtaaggctga cgggaaagag atcgtgcgtt ttctcatgat 1946521 taatattgcc gcgtcaggga tcaccttttt gctgctttat ttgtttcaaa attgcggctg 1946581 ctcgcttttg gtgagtaagc tcgccgccac tatcggcgga atgatgatga attttatcgg 1946641 aaaccgaatc tgggtatttg gagattcgct gaaaaacata caggatcagg agtgaagatg 1946701 aatgagaaaa aaagtgagaa aagcggttat acccgcagcg ggtttaggaa cgagatttct 1946761 gccggcgaca aaggcgcagc ctaaagaaat gcttccaatc gtcgacaaac cagcaatcca 1946821 atatattgta gaagaggccg cagagtcagg aattgaagat atactgatta ttacagggag 1946881 aaacaaacgc tcgattgaag atcattttga tcggtcggcg gaattggaat tcaatctccg 1946941 ggaaaaaggc aagacggaga cacttaagga aatgcagcag attgccgatt tggccaacat 1947001 tcattacatc cgccagaaag aaccgctcgg attaggccat gcggtgctgt gtgcggagca 1947061 ttttatcgga gatgagcctt ttgctgttct cttaggtgat gatattatgg tgtctgaaac 1947121 accggctctt cggcaattaa tggatgtata tgacgtttat ggcacagagg ttgtcggtgt 1947181 acagtcagtt ctccctgagg atgtcagcaa atatggtatt ataaatacat cagggtctca 1947241 agggcatgta tatgaagtga acgatttagt ggaaaagcct tctcctgaag aagcaccttc 1947301 ggaaatcgca gtaatgggac gttatgtgct gaattcttcg atcttctccg ttttgaagac 1947361 aattggcaga ggcgcgggca acgaaattca gctgacagat gcgcttcgtg aggtttgccg 1947421 taaggagccg atccatgccc ggctgctgga aggaaatcga tatgacattg gcgataagct 1947481 gggctgtttt aaagcgagca ccgaaatcgg cttaatgcgt cccgaaatga gatctcagct 1947541 tttggcctat ttagaagatg tgatcaaacg ggaaacgaaa gaaatgctgc ggtaaaaaaa 1947601 ttgtaaccat cttgctcgtc aatcagtcat ataatagtga aaaagattag gacaggttgt 1947661 gaagaatgtg ggcagtttga taagcgaaat tttaacatgg ctgacgaaca tgggatatgc 1947721 gggtattgcg attgggttaa tgattgaaat cattccgagt gagattgtat tagcttatgg 1947781 cggctatatg gtatcggagg gcacgattgg atttattggc gcaattattg cgggtgttat 1947841 cgggggcacc attgcccaga tctttattta ctggatcggt cgctatggcg gcaggccatt 1947901 tctggacaaa tacgggaagt atttattgat taaaaagcat catatcgata tgtcggaaaa 1947961 ctggtttcag aaatacggcg ccggagttgt cttctcggct cgttttatac cggttgtcag 1948021 acatgccata tccattccgg caggtattgc cagaatgcct tttctcaaat ttgtggtact 1948081 gactgtgctt gctatcattc catggtctat cctgtttgtt tatttaggca tacagctagg 1948141 aagccagtgg gatgatgttg agaatatagc aggcacttat acaacaccga ttatgatatt 1948201 ggctgttgtc gtgatagccc tttattttgt gattaagaaa cgtacagcca tatttaaacg 1948261 atagctagcg gatatgcata ggggtgactg acgctcccct atgcatattt ttttacttgc 1948321 gatgttgatt tgccagcttc agattctccg ctaaaaatgc gacaaacact tcatcccgca 1948381 cgagcgatgc ggcataattt ctcttaataa accattctgc ctcttcaaac gctgcgaatg 1948441 tttcgtcttg ggtttctccg ttaatttgaa tattccattc gttgtctaaa gggaaaagaa 1948501 aaaatctcat ttgtgcgcga ttttcatata atgatccatt cgcagatccc tttagattat 1948561 agatgttacg gaaggcatcc ggccgtacag gatcaatacg gaaagcttca gctacaaaca 1948621 actcgtatac ttcatcggtt attgaacagc cggacgcttt tgcatgccct ccgccgccat 1948681 atcggccggc gatttctgac acatcgatgt aatcatgaat ggtgcggaga ctgactcgtt 1948741 ttgaccccat gctcaaaatc gcaatgtaat cgaggtgcgg gttatctttc cctagcctgt 1948801 tccccagctc tgaatggtac gattcagcgt gaacgatgcc tacacagtgt tcgtgaacaa 1948861 aggtttgtac catttccctt ttctttctgc ggaggtagcg ctcgattttt tcgtcttcta 1948921 aatcaagcag tttttcttca aaatcatcga agaaaaattc gtcatgcgtg gaaaggcgct 1948981 ggatcatttt tgcttcaaat tcatcgattg acagcaaaaa gaaaagatca ttaagccgct 1949041 tcgcctgttt ttgatcgtac cgctcccact cccatgtatc gtattggcgg acgagctctg 1949101 tgaattgatc taaggcgttt gtcggtttca tgaagccatt ttcaatgaga tagccatata 1949161 aaagcgatgt cgcggatgtg agccttccat catcgtattc cacctggaca aatccccatt 1949221 catgctcatt caaatgaagg gctgttttat gatggtcaat gagcttcact ttgccccctg 1949281 catgaacata ctcattcaat ctctcttcgt tttcttcatt gacggcgaga tcggtgatga 1949341 ataacgcgtc ctgtctgttg ctctccttcg ctttttctaa aaagtactgc acctgtgcgt 1949401 ttaagccgtt gacagagtta taccggatct ctacgtcttt tccgaacgcc aattttgcta 1949461 cgattccgca tcctactccg tccaagtcgt tatgtgaata taaatgatac ataatgtagg 1949521 ccccttttta tgataaactg acaattgccg ctagaggtgc ggcagccttt atttactatt 1949581 ctaaaaaacc aagcgtttta tgcaatggta attagttgac ataatgttgt tattgtaaat 1949641 atataaagga gcgctttttt tgcgctccta agttcttgct tttacaccgg ataaaccgga 1949701 tgctttcgat tggtaaatgt catttccttt gtcatgtatg ccttgagccg tttggccagc 1949761 tcatcacgca gcgaattggc tgggataaca gcatcaatga tcatttctga agccagacgg 1949821 tagatattga tgtcctcttt gtattcctcc cgtttgctgc tgataaatgc ggctctctct 1949881 tcttctggca gctcggcgat ttttttagcg tagacagcgt ttacagcggc ctcagggccc 1949941 atgacggcga tttgggcggt tgggagcgct agacagcaat ccggttcaaa tgccggccct 1950001 gccattgcat acaaccccgc cccgtaagct tttcggacaa tgacagagag ttttggaaca 1950061 gttgcctccg acatcgcaga aatcattttc gctccgtgtc tgataatccc agcctgttct 1950121 acttttgtgc caatcataaa accggggata tcggctaaga acagcaatgg gatatgaaaa 1950181 gcgtcacata aggtaataaa cttagccgct ttgtctgctg aatcgtggaa taagacgcct 1950241 ccttttacct tcggctggtt tgcaacaatg ccgacaggct gtccgtggat tcgtgcgagg 1950301 cccgtcaata attccggtgc aaataaggct ttgatctcaa aaaatgagtc ttcatctatg 1950361 acccgctcaa tgagctcatg catatcaaaa ggtgcgtttt gattttgcgg aatgacgtcg 1950421 gcaagcggag tttcgaagtg ttttggcggg cgtttctcat gaatgggcgc tttttcttga 1950481 aaatttgccg gaaagtaaga caaataagcc cgcaccagct gtatggcttc ttcttcagtt 1950541 tctgcaagaa tatctccgca gccggagatt gagcaatgca tacgggcgcc acccatttct 1950601 tcgagagaca ctttttctcc aataaccatt tccgccatcc ttggcgaacc taaatacatg 1950661 gaggcgttac cgtctaccat aacgacgata tcacagaagg ccggaatata agcgcctcct 1950721 gccgcagatg gtccgaaaag cagacagatt tgcggaatgc gtcccgataa tttgacttga 1950781 ttgtaaaaaa ttcttcctgc accgcgtctc cctggaaaga cattgatttg gtcggtaatt 1950841 cgggcgcctg ccgaatcgac taaataaatg agcggacagt ttaatttttc ggcgatttct 1950901 tgaattctga tgattttttc aactgttttt gctccccatg accccgcttt cactgttgaa 1950961 tcattcgcca tgacgcaaac ggtttggccg ccgattttgc cgatagcggt tacaactccg 1951021 tcagcgggaa gcccgtctga catacattcc gcaaaaaaag cgtcttctag ctcaatgtca 1951081 tcgtcaaaga gaagggaaag ccgctctctg acaaagagct tgcctttttc ccgattgctt 1951141 tgatgatact tttccgctcc gccttttcga atccgttcag cccgttctgt tcgttccttt 1951201 tcataatcca tcagcattgc ctccctttta tattcccttg tatacggccc gtcttttttc 1951261 ttgaaaggcc tgaagccctt ctctcctgtc ttttgtcggg atggtttgtt catacgcttt 1951321 ttgttcaatc gcaaggcctg tagcaagatc tgtctccaat cctttattga ttgcaaattt 1951381 agcctgacgg acagcgatcg gtccgttggc agaaatggct gcggccagtt cctctgcttt 1951441 tggcataagg tcacaaggag ccgtgacatg ctctacaagg ccgatttctt ttgcttcgtg 1951501 tgcggtcacg cgtctgcctg tataaatgaa ttcttttgct tttcctctgc caatcagccg 1951561 gggcagcctt tgggtccctc cagcgcccgg gataatagct aaccctgttt ccggaagtcc 1951621 cagcacagct gcttcagttg cgattcgaag gtcgcatgcc aatgccaatt ctagtccgcc 1951681 gcctaatgcg cttccattta tcgcagctat gaccggctgc ggcaaggcat caagtaaagc 1951741 cgccgttctt tgaatgagag atacactttc cagaacctga tcttctttca gttttatccg 1951801 ttccttcagg tctgcccctg cacaaaacgc tttttcaccg gtgcctgtga ggatgacgca 1951861 acggatgttt gagttaaatt caatttcctg gataatcatt tgcaggtttc taagcatttc 1951921 cgctgaaaga gcatttgctg cctgaggcct gtttaaggtg atcaacgcca tatgttcatt 1951981 tttaacagta aaaagaatag aatctcccat tgtatgcgtc ctccctttta tcaagatgat 1952041 ttaaacacct gtaaatttct gctcggcagc ggtttgccca ttttttcttc aatccatttg 1952101 gccgcagata gcagtttttc tagctttaca tttgttttga tatccatctg ttcaagcatg 1952161 tacacgatat cctcagttgc ggcgtttcct gatgaacctg gcgcatatgg gcatccccca 1952221 agcccgcctg ccgagccgtc gaacaccgtg atgcccattt ggagtgctgt gaccatgttg 1952281 gccagagcgg ttcctctcgt atcatgaaaa tgcagggcaa tttgattagc cgggaatcgt 1952341 gccaaaagag cttcaagtac agtttccact tgggcgggat tagctgctcc aatcgtatct 1952401 ccaagcgaca gttcagaaat cccaaattca aatagagctt ctgaaaggcg aatgacttgt 1952461 tcaatgggga catctttttc gtacggacag ccgaaaacag tcgagaggta ggctcttgtt 1952521 gtgaggtttg ctttttgtgc gtcgttgttt acttgtttga gtatatggag ggattcagaa 1952581 gtggatttat tgatgttttt tctgttgtgc gtctcgctgg cggacataaa aacgcaagcc 1952641 tcgttaatgc ctccttcaag tgcattctcc agtcctcttt gattcgggac aagtgccgcg 1952701 tacgttaccc ctttttctcg gtcgatgcct tttgctacat cgatagcatc tcgaagcgcc 1952761 ggaatccatt tcgggtgaac gaaggatgtg atttcaatat acgacagccc tgtccgggaa 1952821 agctggttga tccaggttat tttatcctct gttgcgatcc aaacgggctc gttttgtaag 1952881 ccatcacgcg ggccgacttc tttgattgtc acttttttag gatatggcat ggtcttcctc 1952941 caaattattg agtggaattg ctcagttcga gcagtacgtc tccttcattt acaaagtcgc 1953001 cttccttttt tttgacttct tttacgattc cgcttctatc tgcaacgatc gggatttcca 1953061 ttttcatcga ttccaaaatg gctacctcct ggcccttttc gatttggtcg ccggctttga 1953121 cgtggacttt ccacaggttt cctgccattt gtatgctaac cgtcatgaca actgcctcct 1953181 ttataggtgc tgtttcaaaa agtcagtcgt gacatcccct tctttaaatg cctttgttgc 1953241 cgcagcctgt atgaggagcg gaaggtttgt tttgattccc tctacacgat agtcgcgaag 1953301 cgctgtctct agtttttcaa ttgcttctgt tctggtttgg cctttgacaa tcatcttagc 1953361 gatcatcggg tcataaaaag gggtaacggt gctgtctttt gctaccgcac attcgtgtct 1953421 gactcctttt tggtcaggaa gtgaaaacgc agtgatcgta cctggtgacg ggaagaaggt 1953481 cttgggatct tccgcgtata ttcgaacctc tatcgcatgc ccgttccgtt ggatgtcttt 1953541 ttgggagaat gtgagtgtat ggcccgcagc aatccgcagc tgctgctcaa ctaagtccag 1953601 gcctgttatt tcttcagtca cggggtgttc aacttgcagt ctcgtattca tttcgaggaa 1953661 ataaaaattt tgtttctggt caactataaa ttcgatggtg cctgcgttcg tatagccgat 1953721 tgccttcgct gcttttaccg ctgtttgacc gatcttcatt cttagttcat cgtctacaaa 1953781 tggagacggt gcttcttcaa tgactttttg gtggcgcctc tgaacagagc aatcacgttc 1953841 aaacagatgt actgtatggc cgtgttgatc ggccaaaagc tgaacctcga tgtggcgcgc 1953901 atgttcaata actttttcta tatacataga cccgtcaccg aaaaaatctg ctgcgcgctt 1953961 tttgtttccc tcgtacgctt tttttaatgc ttcttcattt tcaacacgct gcattccgat 1954021 gccgcctccg cccgctgaag ctttcagcat gacaggatag ccgatttgac ttgcggtgcg 1954081 gcaggctgcc tctatatctc cgagggattc agaaacgccc ggcaccacag ggacacctgc 1954141 agcctccatt gcttttcgcg cttcaatttt gctgcccatc tttgcgatga tatcagggga 1954201 aggtccgata aacacgatgt tttcttgctt gcagcgttca gcgaaccggc tgttttctga 1954261 taacaatcca tatcccgggt ggatcgcgtc ggcttttgct tttttcgccg tctttatgat 1954321 tctctctata tttaaataac tttcactgac tctcgattcc ccgatcaaat atgcctctgt 1954381 agcggctttt gtatggggcg cgtccttgtc tgcttctgaa taaacagcga ccgttttaat 1954441 gccgagacgg ctgcatgttc ggataattct cattgcaatt tcaccgcggt tggcgatcag 1954501 tacttttgta aacatgattt cacctcattg acttgatgat aagttgaaca tttcaatcgt 1954561 tttttctcgc agtttatatt tttgaatttt gcctgaggcc gtcatcggat agtcatccgt 1954621 aaaaataaca taacgcggaa ttttgtggcg ggcgattttc cctttgcaat aggctttaag 1954681 ctcatcaggt gaaacgcttt taccgtcttt cagtttaatc caggctgcag cttcctcccc 1954741 gaatttggcg tcaggcacac caaccacctg tacatctaaa acagcgggat gctggtataa 1954801 aaattcttca atttcccgcg gataaatgtt ctcgccgcct ctgatgagca tatcttttaa 1954861 tcttccggtg atgcggcagt acccgtcttc atccatgaca gcaagatctc cggtaaacag 1954921 ccatccgtca tgattgattg cttttctggt cgcatctttg tctttataat agcctttcat 1954981 gacgtgatag ccacgggtgc acagttctcc ctgcatgcct ctttgaactt cttgacatgt 1955041 cccgggttct acaattttca cctcagtatg tggcagggca cggccggttg tttcgactct 1955101 tcttatgaag gaatcatttg ctctcgtttg tgtaatgact ggcgaggctt cggtttgtcc 1955161 ataggcgatc gtaatgtctt tcatgcccat cctttcaatc acagctttca tcacttcact 1955221 tggacaggga gagccggcca tgattcctgt tcggagcgtc gatagatcat atgcatcaaa 1955281 atccggatga tgcagctcgg cgataaacat ggtaggcaca ccatggagca ctgtgcattt 1955341 ctctttttct accgttttaa ggacggtaac gggatcaaat tcttgcacgg gtatcatggc 1955401 tgccccgacg gatacacatg ccaaaacccc aaggacgcat ccaaagcagt gaaaaaacgg 1955461 aacagggatg cacatgcggt cttgagaggt taaagccata cattcagcga tattagcagc 1955521 gttattgatg acattgaaat gggtcagcat cacgcctttt ggaaaccctg tcgttcctga 1955581 tgtgtattgc atattaatca cattgtcttt atccaggctg ttcattctct cttcaagctc 1955641 agcatctgtc actgttttcg ccaatatctc tgtatcgtcc caatgataca tgccagacaa 1955701 tcgtttattg ccaatataga tcagcgtttt taaaaaggga tagcgttcag atttcagttg 1955761 gccgggcttt gcttcttgca gttctggaat taaactgttc acgatgtctg gataagaagt 1955821 gcccctgtat gaatccatga taataagcgc cgcggcatcc gattgcttta acaagtaatc 1955881 aagctcatgt gcttgataat tggtattgac ggtcacgagc acggctccga tcttcgcagt 1955941 tgcgaactgg acggcaagcc attcagagat attagaagcc catatggcga cgtggtctcc 1956001 ttttccaatc cccatccgca tgagaccttt agcggtttga cggcacagac tgtcaaattg 1956061 agcgtacgta tagcggatat ttcggtctgg atacacaaca gcatctcgat cgggatacgc 1956121 atcagctgtt tgttccagca gcctgccgat tgtggaatgg atgagttcag ccattcattg 1956181 ttcctccttt cttaatgata ggaaagcgtt tacattttta ttttaaaagc tgtctggcga 1956241 tcacgagacg ctgaatttca gatgtgcctt caccgatttc cattaatttt gcgtcccgca 1956301 gcatccgttc caccccatac tctttcatat agcctgaacc tccatggatt tgaatggctt 1956361 gattgcaagc tcttgtcgcc atttcagatg cgaatagctt ggcgtacgcc gcttctttgg 1956421 tgaacgggcg gttatgatct ttcagccagg cggcttttaa caccatttgc cgtgccagat 1956481 caatttccat cgccatgtca gcaagcttaa attgaatcgc ttgaaaggaa gaaatcggct 1956541 gtccaaactg ctttcgctct ttcgcatatg ccaatgatgc gtcaagggcc gcttgggcaa 1956601 tgccgactgc aagagcagcg atggagattc gaccaccatc cagcgtatat agaaactgtt 1956661 taaacccttt tgttggatcg ccaagtaagt tggccgcagg cactcttaca tcttcaagca 1956721 agatttccgc tgtattcgaa ccgcggacgc ccattttatc gtacgggctc gtaatcgtaa 1956781 gtcctggtgt gtcagttggc acgattaatg cggagatgat gttttttccg tctttgtttt 1956841 tgcctgttac ggcggttaca ataactgtgc gtgcgtagct tgcattagtg atccagcact 1956901 tttcgccgtt gattacatac tcgtcaccat ttgaaatcgc ttttgtttga gtgcctcctg 1956961 catctgagcc ggcatttggc tccgtcaggc cgaatgatcc gagtgctgtg cctgaagcca 1957021 gcggcgtcaa atgcgtctgt ttttgctctt ctgttccgaa gtagtaaaga gggcttgcgc 1957081 ctagcgagac cgctgcagca tagcttaatc cagtactgcc gcaggctttg ccgacttctt 1957141 caaccgctaa ggcatatgaa atcgtatcac cgccagatcc gccgtattct tctggaaatg 1957201 gaatacccat cagaccgagt tcacccattt ttttaaatgt ttgcatcggg aactcgcctg 1957261 tttgatctac atgttcagcg tgaggagcaa tttctttttt cgcaaaatct tttaccattt 1957321 cacgcaccat ttgttgttct tttgtcagct caaaattcac atcgtttcct ccttcacatc 1957381 tttgtaacat cctattaggc gagttctata atcattccct gacaagaaaa gtctgaaaat 1957441 taaaactgaa tcatttttta tgtgataata tcagcgggat gagcaaatac atgcagtagg 1957501 cgcataccat ccatatcgta aacgcaataa cttggccctt tgataaagcc gggaagatga 1957561 ggggaagatt ccaaagggaa atcgtatcca tcaataaacc gaccgctgat ccccatatac 1957621 ctagcttgat caccgcgaac tgtgattgat cgagtttttg atagagaaag aacacaaggc 1957681 ataaaacaag agcagtgccc gctcccaaga gaagaaagtt cggcaaaaag gcttcttcag 1957741 ccggatcagt caacacagca tctccgaaca gcacaaaaaa taatgtggca cctaaccaga 1957801 ctagaaatga aaacgtaaaa cacgtcctgt acgtgtttct cttcgatttt atttttattt 1957861 agtactagtt tctcagattc caataatggt aaatgtccaa acaccgcctc catattcatg 1957921 tgaatctcac ctttgttttt taaaaaattc agcggtttac catcgtttcc tgtcccaaaa 1957981 tcacttttta aaaaaagacg acttagaaag ccgtccttct catttcttat tttgttgttc 1958041 gtttggaagc tttgctttcg ttatgaagcc ggtctgctga agtgacataa tacgtatatt 1958101 tcttgttggg atctgccgtg ttatctaaga aggtttgctg ctcatgtgtt tttctttgcg 1958161 ttgccagcaa tgttctctgc tttttccctt cggctctgta tatcgcataa taggctgttt 1958221 ctttcgtttt ttgatttgat gggtgatctt taatctgcag aagattgccg tttttgtctt 1958281 cggtgacttt cgtaagcttc ggtttttttg gggcggtatt gtcaagccaa ggcatttgcg 1958341 gaaccagtgc cggcttgctg taaagatcgg tgctgagact gtctttgatg ccaagcggat 1958401 ttttgttgag gtccttgagg ctgaaatgca tgcttccttt caccagttca agctggcggt 1958461 tcaaagtgat ttgccgcaca tattcctcag gatcggacca aggcggatca aaattgttat 1958521 tgattttata tgctgcctgg ccaatatata agtgaacagg cctatttttg acttcattgc 1958581 tccaccaatc agccagcacg tcgtaagccg ctgcgttaaa gccgatactc caataaattt 1958641 gcggagcaat ataatcgatg tcgccttctt ggatccaatg ccttgtgtct gcatatagat 1958701 cgtcataatt tctgacgcct gcttttgtat tcgatccggt cgggtcatct gcggcgtttc 1958761 tccatactcc aaagggactg atgccgaatt tgacatacgg ttttgcagct ttaattgttt 1958821 ggttgatttg tttgacaagc tggttcacat tgtcccgccg ccagtcatcg atattagaaa 1958881 aagcgtcttt tccgtattgt tcgtactgtg cttgatcagg aaattcctgt cccgctattt 1958941 tataagggta aaaataatca tccatatgaa cagcatcgat atcataatgt tttacgactt 1959001 cttcaatgcc tttgacgata aaatctctcg cttctggaat gcctggatga taatacagct 1959061 ggtttccata ggcggcaacc caatctggat gttttcttgc cgggtgatcc tcagacaatt 1959121 tattaagatc tgtatgattc attgtaatac ggtaaggatt aaaccacgcg tgaaattcca 1959181 aatttcgttt atgggtttct tcaatcataa atgcaagagg atcatagccg gggtccttcc 1959241 cttggacacc ggttaagtat tccgaccaag gcccgtaagc tgacggataa aaggcatcag 1959301 ccgtcggttt aatctgaacg ataacggcat tcattcccat tttttgcaca tcgtccagca 1959361 gtttgatata ctcctgtttt tgctctttca cagataaccc ttttttggac ggccaatcaa 1959421 tatttaatac ggaagcaatc catacggctc tcagctccct gtcagactgc gcattggcca 1959481 taaacggaac ggaaatgaca aacgttccga tgatcaagct gacaaggaaa cggacaatcg 1959541 acttttggca aaccttcatt ctgtttcttc tcccccatta catcactttc actattcgct 1959601 attacggtat tcccgggcta taaaagggtg attaacagaa tgtctatctc actaaataaa 1959661 cgaaaaaagt cctaaagcat gttgtgaacc gcttttagga ctttttatca ttcatcatgg 1959721 tttgcagact ttttaacaca tcaataagtt ttacgccgac accgacagcc gtttcaagga 1959781 tcgcttgtgc tccggcaatg gctaaaataa agatcagcgg tattgcaata cgaggcaaaa 1959841 aaagatagcc aagtccgatc aagatggcac accaaacacc ggcacaccag tagcaattga 1959901 gcatgtatcc aaagttagaa gccggcacgc ttttttcatc tacatgcccg ttttgatcaa 1959961 caatcctttt ctttttcata aaaggttttc ggataaattc tgtgattttg tcaaatacaa 1960021 tcaaatgtgt cagcctgtaa ctggctagaa tcagcatgat aaaagttaga aaagaaagac 1960081 ggtccattga gaagcctcca agaaaaagga tgatgttatc attcccaagt gtcccttatc 1960141 cattcttgat acaaaaagaa agacggacag agaatggcct ctgtccgcta atccgcttta 1960201 tcgtttgtgc agtattactt gatttgaagt gatcttttct aaaatgtcga ggatgatgtc 1960261 ggcattcttt tcagcatatg ttccttccag catgtcttta tgagcgccaa aacccgtgta 1960321 ctcactatag tttccgcagg cgccttccca tttcgttaag cctgtatgcc cgctggtttc 1960381 ggggtggatt ccagcttcga tgaaatgaat gcttgctttg atgtggcctt cattcagcaa 1960441 ttgtgcccaa tattcctgat agtttctttt tttcttcatc accttttctc tgactgcttc 1960501 aggcagatat gctgcagatt cgtcattacc ggtatcgata ggcaaaggct gttcttttag 1960561 ataagcgtcc acgataatga agtcgctgac ttctaatcct ttgcgctcca tagcctgtgc 1960621 cacttcaaaa gccaggtttc cgcctgcaga gtagcctaat aaaacgtatg ggccctcagg 1960681 ctgtatgtcc gtcatgcaat taacatattg ttcaatgcgg gtgtcttgtt caataaagtg 1960741 aaacccgtat acggctgcct tctcattcag caataaagca aggtctttaa aataaatgcc 1960801 aaatcccgat atcggcggga agcagaaaag attttgcgcg ccgtgctggt tcagtttgat 1960861 cacatgctgt tcatttgctg ctgtcagctg tttagaataa agtttttcgg caagctgagc 1960921 gattgtcgga tgttcgaaca agaaatcaat cggtatgtca atgttctgct gatgttttag 1960981 tgtatgtatg acttgcagtg ctcttagtga atgtccgcca atagcaaaga agtcatcatc 1961041 aatactgatt gtgttaacac cgaggacttg cttccaaatg ttcgccaatt cttcttcaac 1961101 caagtttctt ggcaatatga tgttctgtcg tttggcaggc ttattttctg gaataggcag 1961161 cgcgctgcgg tctatttttc cgtttccggt aagcggcatc cgctccacac gcacccagtg 1961221 ctgcgggatc atatagtctg gaagcacacg cgccaaatcg gcgcgaaaat ccgtatctgt 1961281 ttttttgtga tcaccgacgt aatgagtgta cagctgcgcc tctccatctt tttctctcaa 1961341 tgtcactgct gcttcttgaa cgccttccat ttctaacagg cgcgcttcta tttcggcagg 1961401 ctcaattcgt tttccgcgga ttttcatttg cctgtcaatt ctgctgatgt attctaagtt 1961461 tccatcaggc agccagcgcg ccaaatcacc agtacggtat attctttctc caggcaagaa 1961521 aggatgagga gaaaacacag catttgtcag atctactctg ttcaaatagc ctttagcgac 1961581 tccatcaccg ccaacacaaa gctcgccggg aacgcctatt ggcaaaagac gtccttttgt 1961641 atctaagatg taagcggtgc tattactgat tggttttcca atcggaatcg gccccgcata 1961701 gtctctcttc atttcaaaaa aggttgaaaa agtcgtgttt tccgttggcc cgtaaatatt 1961761 atgaagcgcg agatctggac aggcgtgtct gacggcattc atcagggcag gagagagtgc 1961821 ttctcctccg acatataacg tatggagtcc gcgaaacatg tcagctcgta cctgtgccag 1961881 ctgattaaaa agagctgtcg ttaaaaatag cactgtaatg tcattttcaa gcaaatacgc 1961941 tccaaaccga tcaggtgtca gcattgtcga tttatcaatg atatgaaggc ttgcgccatt 1962001 taaaagtgcc ccgaacattt caaaggtgac ggcgtcaaag ctgatagatc cagtcataat 1962061 aaaccggtca tcaccggacg cagacgtgta attgctgttt ctgacaaggg acacgacatt 1962121 gcgattcgtg atcatgaccc ctttcggccg gcctgttgat cctgaggtat acatgatgta 1962181 cgcaagatca tccgggctgg agctgatatt aatagggata tcgttctctt ccatcaatcc 1962241 ctgcgcatct gaaatgatac atgttcctga gaacgcagcg ttttgctcca atcccttttg 1962301 aacaatcagc atttttgcct gcgtttcctc aagcataaag ctgactcgtt caggcggaag 1962361 ctccgcatca agcgggaggt atgctccccc tgcttttaat acggcaagca cactgatcat 1962421 gaattcggga gaatgtgcag ccaatattcc ggctgtctcg tttttccgaa atcccttttg 1962481 aattaactct ctggcgagcg cattagagcg tttatcaagc tctttatacg aaatagacat 1962541 attgccatac acaagtgcgg tatggtctgg cgtcttttct gcttgttcgc gaaataaatc 1962601 gataattgta tgattctttg gatactccgt ttttgtattg ttgaactgtg tgacaatctg 1962661 ctctttttct gttgcatcaa gaaaagaaaa atcagcaatt ggcatatgag ggtgctgtgc 1962721 agctgtgcta agcgcttgcg taaattgcct cttgatacag ctgatccagg cagcatcgta 1962781 aacgaatgca ttatagctga acttgatgac aagctcttcg ccaggagcaa cgacaagatt 1962841 aaagttatat cctgattgct cggatacttg aacttgatcg atttgcagcg gtgaatcggt 1962901 ttgatcagcg gaatcggcga ttttctgctg taacggatag ttttcaaaga cgataatgtg 1962961 atcaatcagt tcctgtttta atgcggtgtt tgcctgaata tcaaataaag gctggcaggt 1963021 aaacggctca gcttccagca tttctttctg gcagcgtatg agcagctcgt gaaacgtttc 1963081 gtcttggtgt gttttaattc gaatcggtat ggtattgata aacaacccta tcatttgctc 1963141 cacgcctggg atttctgacg gtcttcctga tacaactgcg ccaaacacaa cgtcgtctgt 1963201 gcggttatat tgctgcagca tcacacccca gactgcctga ataagggtag cgagcgtgac 1963261 gccgtgttgt ttggcagtct ctttcagctt gtctgtcagt ggtttattta atgaaaatat 1963321 caaatcttca cggtgataac tttcttttgt ttctttatca gacacacgag gcagaggtga 1963381 tggagcgctg tagtttttta aataggtatc ccagtaggcc gctgcttttt ctttgtctcg 1963441 gtttgtcagc catgaaatat aggtgctgta cggacggaca gggtctaatg aaagcggttt 1963501 tcctgcatga atcgattgat aaatttgcat aaattcctgc ataacgatac ctaggcacca 1963561 tccgtccatt aaaatgtgat ggtgactcca gatacagaca tgctcatctt tagctgtttt 1963621 gaatagagaa atccgcatca gcatgtcttt ttgcagatca aagccttttt gcttgtcctt 1963681 ctctttaaag cgttcaatat actcattctg gtcgtttgtc ggcagatgag aaatgtcttc 1963741 gctgttcaaa tggaattcac gttctgtcat cacgacttgc cgaggtcccg acaaatgcgg 1963801 gacgtgcggc aaaaacacgg ttctgaaaat atcatggcgg tcgataatgg cttgaatgct 1963861 gcgctggaac cagtcatagc tgaggcttcc tttaatggtg aagagcgact gctcaacata 1963921 cgccccctcc tctttacgga ggaaggaatg aaacagcatc ccttcctgca tatgactcag 1963981 aggataaatg ttcttgattt ttttaatggt attcatagtg tctgcacctt tcttcacgga 1964041 ttcattagtg aaaactgagc atatcagcga tctcttgcag ggcgtcctcg gtcagttctt 1964101 gatcatcaaa atcactgatc gtcttttctg tttcgctttt gttctggcag tgttcgatca 1964161 gctgtaataa aaattgacgg catgtttcgc taagctgttc gatggttttg cgctgaaagc 1964221 gggcattgtc ataagtcata ttgacagtca attttccttc tgcagcgatt gcgctgatat 1964281 ccagcgactg ttcacggttc catgttgtgc tgatatcacc tccggcaccc agcggagaga 1964341 atgagaaggc gtcctcctca ggtacttcag ctgtgcggcc gctttcaaat tgaccaagat 1964401 aattaaagct gatttctggt gcacctgtga aattgatgtc ttttttgcca ggcggagtca 1964461 aatatttgat gacaccgtag ccgaatcctt tgtcaggtac acgtctcagt gtatcttttg 1964521 ttgtttttag cacatgaacc atgctttctt ccgaatctgg caagtctgcg ttcagtttaa 1964581 tcaataacgg ataaatggcg gtaaaccatc caatcgtccg gctcacatct attcctttta 1964641 atacatcctc tcgcccgtgg ccctctaatg atagtttgaa ggcggattga ttggtccaat 1964701 ggcgcagcgc aagaatgaca gaagcgagca gcatgtcctg cgtatcagtg ttatatgcgc 1964761 tgttggcgtc ttttaagagt gctgctgtct ctttatcgtt taaggtaaac gaaattgtgg 1964821 accgttgtcc ctcgtgtgct ctagttccat cgatttgatc aaaaggcaat gcctctgttt 1964881 gatactcttc ggcttcgcgc caatacttga gctgtttcat tagctgctgg ctttcagcgt 1964941 agtcagagag ctttttcgca tacgctttaa acgagcttgt tttaggcggc agtttgatat 1965001 cctccccgcc agcagcttgg cgatacccta aagccaaatc ttcaagcaga acccgccatg 1965061 agatgccgtc aacgacgagg tgatgagcag ataaaaataa gaaatcaccg tcaattgtgt 1965121 ggaaaagacc ggcttgcagc agcggaccat tcttcaaatc cattttctgc tgaatatcaa 1965181 gtacatggcg cttgataaga ggttcatacg gtctatttcc atcagtgccg tccggagctg 1965241 acaaatcaat catctgaagg ccgtacaacg cgtcgtccga atgactgagc ggccgattat 1965301 attgatccca ctttccttgt tcattctgtg taaacaccat tcgcagcgca tcatgatgac 1965361 acgttattgc ttttaacgtt tttcgcagtg cgtcttcttg tacagaggtg cttcgatgca 1965421 gcattacgga ctgattaaaa tggtgttttt cttttatatc ttgagaaaga aaccattttt 1965481 gaacaggcga ccattgtacg tctccctcaa ccgcagcttg gctggaactt gtatctgaat 1965541 cacggatata agctgccaat tcttgaatgg tcggatggct aaacaaatct ttcactgcca 1965601 tttgcttgcc tatccggtga agccgcgcag atacctgtaa cgctttgatt gaatctccgc 1965661 caagttcaaa gaacgaatca gctgttccga tcttttctgc ccccagtact tctttccata 1965721 tatctgccag tatttgttcc attttgctgg atggcgggag gaatggacgt tcaccttcgt 1965781 ggttgtatac aggttttgga agtgctccgc gatccagctt gccgtttggt gacaatggaa 1965841 gtgagtccag tttttcaata aacgcagggt gcataaacac cggcagcttg ttttgtaatt 1965901 ctgagcgtac agcatttgtg ctcaaccctg gttttgtcac cacataagcg cttaattcgg 1965961 tttgtcctga cgctgttaca tgagcaacta ctgcggcgtc ttttacaccc tttatacacc 1966021 ggatgaccga ttcaatttct ttcgtttcta cacggtatcc tctgattttg acttgatcat 1966081 cgattcttcc gagatattcg agtgtaccgt cggccatcca tctggcggcg tctcctgttc 1966141 ggtacattcg tgcttcgggt ttaaatggat tctgcgtgaa tgctctctct gtcagttctg 1966201 gaagattaac gtaccctctt gcaagccctg ttcctgctat acaaagctct cccgcaacac 1966261 cgattggctg aagctgatga ttgctattta aaatcagcac ttgagttccg tcaatcggct 1966321 ggccgatgct tacgtatgcc tgcttttcca tatgtctcat gacggtagtc gccacgctgt 1966381 tttctgtcgg tccatattcg ttggcgagtt cggtatgcgg acatatagct aagctgcggg 1966441 cgatcaattc gcggtcagcc gcttctcccg ccagtgtgac gactctaagc gtctttacat 1966501 cttccggctg cactacgtcc aaaagcgctc gatataaaac aggcacaata atcatatgtg 1966561 taatccgttg acgagacagc tgatgcttaa tggccagaat atccttcgct tcctcttcat 1966621 gaagcaaaac ggcttttgca cctgacaaaa gcggtgtaaa catactagtt ataaagccgt 1966681 caaatgagaa agaaaagagc tgcagaatgg tatctgtctc gttgaatgca taagcgtttc 1966741 gccgccactg aagagtgtta gcaatccctt tatgctcgac cattacccct tttggacggc 1966801 ccgtcgttcc tgaagtataa atgatataag ccaaatgatg ggcagacgac atttgcggca 1966861 gcggcgattt gtcgtcttcc tctacgcttt ctatcgtcaa gatctctcct tcaaagtcag 1966921 caagtactcc cagatccgct tcatttattg tcatcagcag tttcgttccg ctgtcgctga 1966981 ggatatagcg tttccgttct ttcgggtatt caggatcaat gggaacgtaa cagcctccgg 1967041 ctttccacac accaagtatg gatgctatca tactgaacga acgatgcatc atgatgccta 1967101 ctggtgtgtc cggcttaaca cctcggctgc gcaatgcacg tgcgattcca ttggaccact 1967161 cgtcaagctc ctgataagtg agtgttttgt ctccgctgac aagtgcagaa gcttttggtg 1967221 ttcgtgcagc ttgctgctca aacaattgac tgattgtttg aactccgtat tgattcgctt 1967281 gcccggtgtt aaactcatta agcagctggt gccgctcttc ttgggtcagg atgtcgatat 1967341 ggttgagtgt caccttcggg tttttgccga tgatgctaag tacatttgtt aaatgcgatg 1967401 cccagcgttc aatggtggtt ttctcgaaca atgcggttga atattcaaaa aggaaatgaa 1967461 tgtttccgtc gccctcagat gcctgtagtg tcaaatcgaa tttagaaacg agatgagaaa 1967521 cttgtgccgg cttcatttgc aaatcatgaa gatgcaatgg ctcgtaatca ttattttgaa 1967581 caactaacat cgcatcaaac actgggttcc ggctcatatc tcgtgtcaat tcaagcttat 1967641 cgacaagctc ttcgaacggg taattctggt gctcaaaggc ttccaatgct gtctcacgca 1967701 cttcctgcaa atactgtacg aatggcttcc cgccctccgg gcgcgtccga agcgccagcg 1967761 tgttcacaaa catgccgagt atcggctcaa gatccttgtg cggccggccg gcgattggcg 1967821 agccgacgat gatatcttcc tgtccgctta agcgtgacaa gaacgcggtg taagccgcaa 1967881 ggagcaccat gtacagtgtg cttccgtttt ctcgtgccag cttgtgaagg cctgatgcaa 1967941 cctctggttc cagcgtaaat gagaccttgt cacccgcgaa gcttcgcacc ggcgggcggg 1968001 catgatcagc ggggagatcc agcacaggca gctcgccctc gagctgcttc agccagtacg 1968061 cctcctgcat tttgtacgcg tctcctgttt tgaatccttc ttgccatacg gcataatctt 1968121 tatattgaat gcgcagcgcc ggaagcttcc gattattgta cagctcgccg aattcttgaa 1968181 tcagaatgtt gacggaaaca ccgtctgaaa tgatgtgatg catatcaacc agcaataggt 1968241 gccgctcatc tgataccttt acgatttggg cacggaacag cggcgcttgg ctgagatcaa 1968301 acggtttgat aaatgcggct gcggcctcct gttcggttcg tgcgccgaga actgtagtct 1968361 gtaacgtaaa cggcacctcg tcatggatgc gctgcaccgg atcgcctcct tcgtcctgtt 1968421 cgaaggaggt tcgaagcgac tcgtggcgct tgatcagctc ttggaaagct ctgtccatcc 1968481 tttcagggtt gagcttccct tcgagctcta acacagccgg catattgtag cctgtccctc 1968541 cgtcctccag ctgctgaagg acataaatcc gcttttgggc agaggaaacc ggataggttt 1968601 cctgtttttc agcgggctta atcgcttcat atggactgtc cgttccttca cggataacgg 1968661 tagccagtcc ttctaccgtc ggatgggcaa acacatcttt tagcggcacc tgtacatcga 1968721 attctttggt gatccgtgag acaagcgccg ttgcttttaa ggaatgtccc ccgcggtcaa 1968781 aaaagttgtc gtgaatcccg acagggccat ttttcagcac gtcctcccac agctgagaaa 1968841 gcttcatctc agtcacgttt ctcggcgctg tgtaggtctc cgcatctgcc gctccgccag 1968901 gagctggcag ggcgtttcgg tcgagctttc cgcttggcgt aaccggccac tgttccatct 1968961 ctatcatata ggctgggacc atgtagcccg gcaacagtct ctcaagctgc gctcggactt 1969021 cgtttctttg gagcccttct acataagcgc ataattccgg ctccccgctg tctgtccgta 1969081 cggtaacggc cgcctctctt acaccttcta tacttcttag tgccgcttca atttctcccg 1969141 gctcaatccg gtagccgcgg attttcacct gatcatccgt gcgcccgagg aattcaacat 1969201 tcccgtcagg gagccagcgc gccacatccc cggttttgta catgcgttca cccgggtaaa 1969261 acgggtcttc aagaaaacgc tcctccgtta atgccggccg attcaaataa cctctggcaa 1969321 cacccgctcc ggctatgtac agttcgccga tacatccaac aggcagcatc cgctgattct 1969381 gattcaggag atataatctg acatgatgaa caggttttcc aattgggatc cgttcaagtt 1969441 tttcatgcgg cggacaatca aagaatgcag cttctacggt tgcttccgtt ggcccatagg 1969501 aattggttat tgaaacattt ggaagcaact cgtaaaatcg ggagacaaga tgggtcccca 1969561 gctgttctcc cccagaaaac actcgcttga gtctgtttgt cttaatcggt acagagcgat 1969621 attttatatg ttctaaaaat gcatggagca ttgaaggcac aaaatgcata gctgtgatct 1969681 tttgttcttc tatggccttc gcgatcactt caggttcttt ttcgcctccc tgaggaagca 1969741 gataaacaga agctccggca taaggccacc aaaacagctc ccatattgaa gcatcgaatg 1969801 aatatgatgt tttgtgcata atcatatctg aatgctttag ctgatagcgg gactgtaggg 1969861 aattcaaaaa attcaccgct gatcgatgtt caatttcaac acccttaggc atcccggtag 1969921 agccggatgt atagatgaca taggctaaag attgcgggag aacatccaca ttcggattgg 1969981 acaaacgatg tgccagtccg ctatttgtct gattgagata gacaatctct cctgtaaatt 1970041 ccggaacatg aaggccggca gactgaagca ggagaatgtt tgtaccgctg tcctccagca 1970101 gaaagctgat tcgttcttcc ggataatccg ggtcgatggg cagataagcg ccgccagctt 1970161 taagaatgcc ataaatgcca agcagcattt caggtgaacg ctttcctata atggcaacag 1970221 tcgtttcggg ttttaccccc cgtccgatca gctcccaggc gatacggtta gcctgttcgt 1970281 tcaattcttt ataggtcatc actccatctt cgaagataac ggccgcctga tcaggcgttt 1970341 tttctgcctg ctgttcgagt gcatagtgga gcgtttgatt cattgaatag cccgtctcct 1970401 caaacagatg gcatgattca atgaaatctc gctcttcttc ttttgttaag attggaatat 1970461 tgtccaattc tgtttcagga ctggcagctg tatgttccac aagcgtggtg aaaaggctgg 1970521 cccacctttg gatggtttct ttctcaaaca aagctgtact gtattcaaac tgacagaaaa 1970581 gctcggaatc atgctctgta acgtataggg aaatatcaaa ttttgatatt gggtgctcca 1970641 agtcgttcca ctgaagctgt acatcattca tttttagctt ttgctgttcc atattctgaa 1970701 ggactagcgt tgtgtcaaac aaaggattcc ggctcatttc ccgctgcaca ccgagtttgt 1970761 ccacaagctc ttcaaacggg taatcctgat gctcatacgc ttctagtgcc gtctgtctga 1970821 cttctttcag aaattcctca aatgtcttat tacccgccgg gcgtgtgcgg agagccaatg 1970881 tattgacgaa catcccaaga acagcttcaa ggtcggcatg gggccgtccg gcgataggtg 1970941 aaccaatcac gatatcatcc tgaccgctta accgagacaa aaaggctgaa tacaaagcga 1971001 gaagcgtcat ataaagcgtg cttctgtttt tatgggcgag ccgctttatg cgggccgtga 1971061 tctctttgtc caattgaaag gttacttttc cgcctatgaa ttgccgttct gccggacgtc 1971121 gtttatctgt tggaagctcc agtataggaa ggtccccgct aaactgctgc tgccagtaag 1971181 tctcctgctt ttggtacgag tctccctttt taaatttctg ctgccatacg gcgtaatctt 1971241 tatattggat ccgcaatggc ttaagctgcc ggtttgcata aagatcggta aattctcgga 1971301 ttaggagctg aacggatacg ccatctgaaa tgatatggtg catatccacc agcaatacat 1971361 gcttctcgtt tgacacttct ataaggcctg ctctaaataa tggcgcctgg ctgagatcaa 1971421 agggacggac aaatccctcg atagtggtct ctttacttaa cgtaaacggc acttcggtgt 1971481 ggatacgctg aaccggctcg tcatcagctc cggatacaaa ggaagttcga agcggctcat 1971541 gccggctgat cagttcttta catacagcag acagtttggc gacatccagt gcaccttcca 1971601 gttctaagac cgcaggcatg ttataggcga caccctcatc aagctgttga agcacataga 1971661 ttcgtttttg ggccgaagat acaggatatg tatccctttt ttctgctggt tcaattgctg 1971721 catacagatt ttgttctgcc tctcgaataa ttaaagctaa tccttcaaca gtcggatgag 1971781 caaagatgtc cttaagtgaa acttgcacat ggaattcctt tgcgatccgt gacataagca 1971841 ctgttgcttt taacgagtga ccgccattgt caaaaaagtt gtcttggatg cctatatgcc 1971901 cattctttag cacatcttca aatagttgcg aaagctttgc ctctaacaga tttcgagggg 1971961 cagtatatgg gtttccgctg attgaagcat ctggctccgg aagtgctgcg cgatctactt 1972021 ttccgtttgg ggtaagaggt atgctgtcaa cccatatcca tttcgccgga atcatgtatt 1972081 ctgggagctc actagccata taactgcgta aatctattgt gttcagcttt tgtacactgc 1972141 aatagtaagc gcataattca tgttcaccgt tttgatcttg ccagatgaga atggcagcct 1972201 cactaatgtc cggatgattc attagcgtga cttcgatttc ttgcggctca attcgataac 1972261 ctctgatttt cacttgattg tctgcccgtc cgatatattc gatgttgccg tcttcaagcc 1972321 gtctggccaa atcacctgtc cggtacatga tcacatcagg cttgaatgga tcggatgaaa 1972381 atttgtcgct tgtcagttta tcgtgattga catatcctct ggcaacactt gcgccggaaa 1972441 tatagagttc gcctggtacg ccgcatggct gaagctgttt ttgatgattc aaaatatata 1972501 gatcagtaca gcctatcggt ttaccgattg gcggaagctc aggaataggg tctccaggat 1972561 gaatggtata cgtagatacc acatgagttt ctgaaggtcc gtaatgattg tgcaggtgta 1972621 tgccgcgttt acgcaacaca tcttggaaaa ggtctgaaat cattaattgt tccccggctg 1972681 cgatcaggtg tttgacgcca tcaggaaacg agttcgcaag ttctcgctcg ctgaaaatca 1972741 ttttgataaa agcagttggg agaaacacaa tattcgtctg atgcttgttt ataaatgcaa 1972801 acagctgagg cacatctctt tttatggctt ctggcacgat gtggagtgtg ccgcctttca 1972861 gaagcgcaga aaatatttct tgatagcaga cgtcgaagga aggcgtcgca aattgcagaa 1972921 catctgcttc aaagtcaatg ccggagtgag tatattcgaa cttcagcaag ttagccatgt 1972981 ttcgatgctc aaattgaaca ccctttggtt tacctgttgt gcctgatgta taaatcatat 1973041 acagcagatc gtcagcattg ttgactgact ttatgttact gccgtctact ttgctttcga 1973101 tatcttctgg atgagtgata atgtaattgt cttctaacga tgagggaaga tgcgcttgtg 1973161 aaacaacatg cgaacagccg caatcatgca gaatataacg gattctgtca gcagggtaat 1973221 gcggatcaac cggaacaatg gcgccgcctg ctttcaagat accaagaaca cctgtgataa 1973281 acgccgctga gcgttccatc ataatcgcaa cgggttcctg tctcacaacg cctttcattc 1973341 gtaaatgccg tgccaatctg ttagccgctt tattcagttc tctgtatgtt aatgagcagg 1973401 cttgatcaat tacagcatga gcatctggtg tcttttccgc ttgcttttca aacatggcat 1973461 ggatggtttc gtaaactggt gtttgatctg tgatttctcc aatcagctgc cgcttttcag 1973521 tatctgtcgt gatatcgatt tcttcaggtg gaagattcgg attatttaag atttgtgata 1973581 cagcattcag aagatgctct ttgacagaga gcacaaaaga ccgatcgtgc tgctccgcat 1973641 catagttcat tttgatatga atttcttccc ctggcgccac cataagataa aagctgtagt 1973701 tggtttcatc tgcgacagtg aaattatgaa tctgaaaaag atcagaagca tgttcctgtt 1973761 tgttcagcat ttgaatctct tgctgcaccg gatagttttc aaatacgaga atatgatcaa 1973821 tcagcccttg cttaacagct gagcgggatt gaatctcata taaagggtgg tagctgtacg 1973881 cttcagcggc aagacggtct ttttgcatat cttttataag ttgaagaaaa ggcgtttttg 1973941 ccccctgcac ccgaaccggc atcgtattaa tgaaaagacc taccatatgt tcaatgcctt 1974001 cgatttctgc gggtcttcct gaaatgacag aaccgaatac ggcgtcatcg ttattattat 1974061 atttttgcag cagaatgccc caaatggtat gaaaaatcgt actgagtgtc acttcttctc 1974121 tagcagcaag ctctgaaagc ctgctgcttt cttccttaga gaatgaaaat gtaacgtgtt 1974181 cctgcctgct ttttcccttt gtttttttct gcttcgggag cacggtttgc tgttcgtggc 1974241 cggaaagata atgatcccaa taagaaaccg cctgctcttt gtcttgctcc atcagccatt 1974301 tgatatactt tccgtatggc tggaccggct ccaatgttat tggggatgca tttacataag 1974361 atgcgtaaat atgcagaaac tcctttagca caatgctgag gcaccaaccg tccatcatga 1974421 tatgatgaaa ggtccaaatg caagagtact ggctctctcc tgtttgaatc agagcgatgc 1974481 gcatgagcac atccttttgc aaatgaaacc cccggtcccg gtccttttct ttccattgct 1974541 cgataaactg tgattgctcc gcctcgttta aatgagtaat gtcttcttcc agtacgatga 1974601 catttcgttc tctcagaaca acctgctggg gggaggaaac attttggctg ataaaaatcg 1974661 ttctgaaaat atcatgtctt tctacaagag cgttgatgct gttttgaaaa aactgcgggt 1974721 tgacttttcc ttctattgta aaagaagctt gctcaacata cgcctgtgaa tctttttgca 1974781 ggagggaatg gaaaagcatc ccttcctgca tgtaagacag cggataaata tcctgaattg 1974841 aattcgcttt tgtcatgttc atgtctcctg tcacgatttt ctacaattct tccaccaagc 1974901 tggatatgct gtccaagtcc tctgccgtta atgattgact gctgaaatcg ctcagtgtct 1974961 tttctgcttt ctgttgaccg gcgcagtgtt tcataatgtc cagcaaaaag tgttcaatcc 1975021 tgttaataag ctgttccatt gtgtttctgt gaaagcgggc tggcggataa ctaagattga 1975081 aatggagctt tttgtctgct gccattgcac tcatctcgat gatttgctcg cgcttccatg 1975141 tatgagtgat atcctttccg ctaccaaggc ttgatgggcg gaaggtgtcc tgtctttcga 1975201 tgtcgttgaa ctggcccaaa tagttaaagc tgatttcagg tgtttttgaa aacgtaatgc 1975261 ttttattttc agggtgtgta aggtatttca gcataccgta acctacccct ttgtttggta 1975321 tccggcccag tgtatcttta acggttttta ctgaggttcc gagctcatcc ctatgatttt 1975381 caaagcttat gagggccggg tacatggatg taaaccagcc gaccgtcctg cttatatcta 1975441 actctggcag aatgtgttct ctcccgtgtc cttccatagc gatacggagc ttgcttcctc 1975501 ctgtccattc acaaatcgcc aaggatgctg cggttaacag aatatcttgt gtatctgtgc 1975561 cataggcgtg attgacgttt tgcagcaaga cggcggtgtc tgcttcagtc agtgaaaagc 1975621 ttaatgagtc ccttttgctg aagtcgatgt tcacatgatg cggtatttca tagggcagtt 1975681 ctgcggcttg ctgttcttct acacttcgcc aatacgcctc ttcgcgaatc agcttactgc 1975741 tttgggcata ttcctgtatg cgtcttgcgt attcctggta ggaatccgtt ttaggcggaa 1975801 gctggatcgt ctggcctgca gcagcttgtt gatatccggc tgacaaatcc tccagcaaaa 1975861 tccgccatga gacaccatca acgacaaggt gatggatcgc aaggaacaag taatctccgg 1975921 tcagtgtttt aaacaaagcg gcgtgcaaca atggtccttc ctgcaaattg atgctttgct 1975981 gaagatcggc aacttcttgt ttgattttcg tctcccagcc gctttctgac tgtgaaagat 1976041 cagagattct taagctgtat agctgtgact catgaatgcc ttggttgatt tgaatccatc 1976101 gcctgtcatc gttgcgataa accatccgaa gcgcatcatg atgctccgcc agttttttca 1976161 aggctggtct aagggcgttt tcagacaaac gtccagaatg gaatagcatg acagactgat 1976221 tgaaatggtg tctttcttca atatcttgtg aaaaaaacca ttgctgaaca ggcgtccaag 1976281 gaacgtcacc ctgaatgggt ccttgctcta tgattctctc tgacttacgg ataaatggtg 1976341 ataagtcctt tatctttgga tgacggaata aatcacttac ctgcaagctt agtccatagc 1976401 gcccaaggcg tgcagaaact tgaagggctt tgattgaatc tccgcccaat tcaaaaaacg 1976461 aatcctctat tccgatcctc tggatgccta gaacctcctg ccagatcaat gccagctgct 1976521 cttcaagttc gttgcgtggc gggatgtatg tttgtttaga tgcgacatct ggttcaggca 1976581 gtgctttccg gttcaatttg ccgtttgatg tgagcggaag agtctccatt tcaatgatat 1976641 acgccgggat catatagttt ggcagcgaac gcgcgagaag agaacgcact tgttcagcat 1976701 tcgtgcctgc ttttacgctg atatagccaa acagctcttt gctcccggtc tgggctgtac 1976761 gtgctaacac tgcggcttct ttgaccccgt ctatttgacg aagtgctgtt tcgatttcac 1976821 ccagctccac ccgatagcct ctgactttta cttgatcatc aatacggcca acgtactcaa 1976881 ttgtgccatc ggaaagccag cgcgccagat cacctgtgcg atacagtcga tcgccaggtg 1976941 caaatggatg tgggacaaat ttctctttcg ttaaatcagg acggcccaaa tatcctctgg 1977001 cgacgccatc tccgccgaca caaagttcac cgacagctcc gaccggctgc agcactcccc 1977061 attgatttaa gataaaagcg gtggaattac caaccggccg cccgatcgga atggaaagtt 1977121 catatgtttt ttgaatgtga aggcatgtcg aaaaagttgt attttcggta gggccatatc 1977181 cattccatat agatacttca gggcagacat ttctgattcg attgacgtgg ctcggcgaca 1977241 aagcttctcc gccaataatc aaatgtttca gctgtgaaaa tgtttgttca ttttgctctg 1977301 tcaaatgatt gaatagagaa gatgtcagcc aaatcgttgt gattccttga tgttctatgt 1977361 acctcttaag ctgatgggaa tcgagaaatg tttgttgatc ggacagatgc aaagcggcac 1977421 catttagcag cggtccgaaa atttcaaatg acccaacgtc gaaaccgatt gatgatgtca 1977481 tcagaaggcg gtcttcaggt gtaaatgtaa tataattgct gtttttaaca agacgaatta 1977541 cacttcgctg ctcaatcatg acaccctttg gtttaccggt tgatccagag gtataaatga 1977601 tatatgcaag tgaatggggc cctgctgaag attcaacgtt cttcgcctct ccttgctttt 1977661 gaatatcttc gattatgatt tgttcacatt caatgcctaa tagccgtttt tctgtttttt 1977721 cagattgaag gagtaatgct gccctgctgt cagacagcat ataagctatg cgttcaacag 1977781 gcagattaga atcgataggc agataggctc ccccggcttt tagaatgccc agcattcctg 1977841 caatgagttc tggtgttctg cctgtcaaca aggctacaac actatcaggc cctacgccct 1977901 ttatctgtag aactgaggca atttgatttg cccagctgtt caggtcctcg taagtgaata 1977961 cttgggtgtc gctgacaatt gctacagcat taggtgtttg ttctgcctgc atttcaaaga 1978021 gtctgctgat ggtttcattt cttggataat ctatttttgt acgattgagc tcgtggataa 1978081 ggtaatgggc ctcatcctca ttcaggatat ttattgttcc gagagcggct ttgttgtctt 1978141 tgatgatgga gagtaacata ttgttgaagt attgaagcca cttttctatc gtttttttct 1978201 tatataagtc agtactaaac tccatttgga acgtcagcaa accgcggggc tgttcctggg 1978261 catatagggt taaatcaaat ttggacgttt gatgcccatt gtttgctgca ggtttgagac 1978321 aaagttcatc cagctccaac gattcctgat ccatattttg aagaacaaac attacgtcaa 1978381 acagcggatt tctgctcata tctcgtgtca attcaagctt atcaacaagc tcttcgaacg 1978441 ggtaatcttg gtgctcaaag gcttccattg ctgtctcgcg cacttcctgc aagtactgta 1978501 caaacggctt cccgccctcc gggcgcgtcc gaagcgccag cgtgttcaca aacatgccga 1978561 gtatcggctc aagatccttg tgcggccggc cggcaattgg cgagccgacg atgatatctt 1978621 cctgtccgct taagcgtgac aagaacgcgg tgtaagctgc aaggagcacc atgtacagtg 1978681 tgcttccgtt ttctcgtgcc agcttgtaaa ggcctgatgt aacctcttga tccagcgtaa 1978741 atgagacctt gtcacccgcg aagcttcgca tcggcgggcg ggcatgatca gccggaagat 1978801 ccagcacagg cagctcgccc tcgagctgct tcagccagta cgccccctgc gttttgtacg 1978861 cgtctcctgt tttgaatcct tcttgccata cggcataatc tttatattga atgcgcagtg 1978921 ccggaagctt ccgattattg tacagttcgc cgaattcccg aatcagaatg ttgacggaaa 1978981 caccgtctga aatgatgtga tgcatatcaa ccagcaacag gtgccgctca tctgatacct 1979041 ttacgatttg ggcacggaac agcggcgctt ggctgagatc aaacggtttg ataaatgcgg 1979101 ctgcggcctc ctcttcggtt cgtgcgccga gaactgtagt ctgtaacgta aacggcacct 1979161 cgtcatggat gcgctgcacc gggtcgcctc ctgcgtcctg ttcgaaggcg gtccgaagcg 1979221 actcgtggcg cttgatcagc tctttgaaag ctctgtccat cctttcaagg ttgagcttcc 1979281 cttcgagctc taacacagcc ggcatattgt agcctgtccc tccgtcctcc agctgctgaa 1979341 ggacataaat ccgcttttgg gcagaggaaa ccggataggt ttcctgtttt tcagcgggct 1979401 taatcgcttc atatggactg tccgttcctt cacggataac ggtagccagt ccttctaccg 1979461 tcggatgggc aaacacatct tttagcggca cctgtacatc gaattctttg gcgatccgtg 1979521 agacaagcgc cgttgctttt aaggaatgtc ccccgcggtc aaaaaagttg tcgtgaatcc 1979581 cgacagggcc atttttcagc acgtcctccc acagctgaga aagcttcatc tcagtcacgt 1979641 ttctcggcgc cgtgtaggtc tccgcatctg ccgctccgcc aggagctggc agggcgtttc 1979701 ggtcgagctt tccgcttggt gtaaccggcc actgttccat ttctatcata taggctggga 1979761 ccatgtagcc cggcaacagt ctctgaagct gtgcacgcac ttcgtttctt tggagccctt 1979821 ctacataagc gcataattcc ggctcgccgc tgtctgtccg tacggtaacg gccgcctccc 1979881 ttacgccttc tatgcttctt agtgccgctt caatctctcc cggctcaatc cggtagccgc 1979941 ggattttcac ctgatcatcc gtgcgcccga ggaattcaac attcccgtca gggagccagc 1980001 gcgccacatc cccggttttg tacatgcgtt cccccaggta aaacgggtct tcaagaaaac 1980061 gctcctccgt taatgccggc cgattcaaat aacctctggc aacacccgct ccggcaatgt 1980121 atagttcgcc ggcgacaccg gaaggctgta cggctaaatg cggatctaaa acatacaaac 1980181 gcgcaccagg tacgggcttc ccaatcggaa tccgcaaacg gtctctgtcc cgttctggat 1980241 ctaacacgta aaatgccgcg tctaccgtgg cttctgtcgg cccgtagcca tggattaatg 1980301 atacctgcgg caatacagaa gcaaaacggg ctgccgtacg cggcgcaagc ggttcacctc 1980361 cggcgaatac acgctttagg cttgtcctgt cactcagcct ttcgatttcc gcttgatcga 1980421 gaaagctgtt cagcatagcc ggaataaaat gagccgttgt cacgttttcc tgatgaatgg 1980481 cttgtacgat caatgcggag tctttttccc agccgggcgg aagcagatac gccgaagcac 1980541 cggaaagagc ccaccaaaac agctgccaca cagacgcatc aaaggaaaaa gaggttttca 1980601 ccatgacaat gtcatcttcc gaaagccgaa actggtgctg catgccggtc agaaaggaaa 1980661 cagcctggcg gtgctcaacg gccactcctt tcggctgccc ggtagagccc gatgtataga 1980721 tgacataggc gagagatccg tcgctaacag aagcagacac atgacgtttt acttcttcac 1980781 actcaagaga tgtcatgtcc acttcaagcg tttcgccaga aaagtttggt gcggagcatc 1980841 ccggctgtgt cagcaagagc gatgccccgc tgtctttcag catgtagctc agccgctcct 1980901 ttggatacgc aggatcaagc ggcaaatacg cccctccggc cttcaataca gcaaggacag 1980961 cgatcagcat gtcaggtgag cgttcagaca ggacaccgac gatactttcg tttgtgacgc 1981021 cgcgtgccgc aaggtgcgca gccagccggc tggcgtacat atcaagctca gcgtatgtca 1981081 gcgaaccgcc tgaaaagcga atggccagcc gctccggtgt gactgccgcc tgtcgttcaa 1981141 acagcccatg cagggttggg gcttcaggtg aaacagatac tgtcctgtta ttttgagaaa 1981201 cgattttccg tgttttgtcc tcatctagca acgtcatctt tgacacagga agagatggat 1981261 cagagatgac gtcagagacc atgtgcagca aataatcttt tatttcggac atcatgcttg 1981321 gttgataagc gctggtctga aaatgaatcc gaacgtacaa ggtacggcct gggatcactt 1981381 tgacactgca actataattg gtcacctctt ccatctcaaa atctttgacg gagaaatcaa 1981441 atgaccccgc ttgattcagc tcttcgatct cttgctgggt aggtgtattt tcaaagacga 1981501 taatatgatc gatcaactct tgctttagag cactctgcgc ctgaatatca tacaagggaa 1981561 agtaactata ggcttctgcc tcattcatgt ccttttgcat tctcctgact aggtcagaaa 1981621 aagacagaga atcactttgg gctcgaatag gaatggtatt gataaaaagc ccgaccatgt 1981681 tttccacatc ttttagctca gaaggtctgc ctgatataac tgaaccgaac acagcatcgc 1981741 tgctgcgatt gaccttttga agcataatcc cccataaagc ttggaaaaca gtgtttagtg 1981801 tcgcaccaga agctgctgcg attttctgta attcggcggt ttctttttcg ggaatggcaa 1981861 acgtgatctg ctgtagtgtc ccattcggaa tttgatctgt tcttttcggc aggggtgtag 1981921 atttttcgaa atgctgaagc ctctttttcc agtactcagc tgcttcttca cgatcttgct 1981981 gcatcagcca tttaatatac gtcccgtacg gctgtacggg aggcaaatca ggaagctggc 1982041 ctttacccag cgcttgataa atatggagaa agtctttaat gacgatgcct aaacaccagc 1982101 catccattaa aatatgatgg tggctccaga tacagacata atgatcaggc gcccatttta 1982161 aaatagatat tctcatcagt acatccgttt ggagatcaaa gcctttggat ttgtcctgct 1982221 ctttgaatgc ctcggtacaa tgttctttat ccctttcatt gagatgggaa atatcttcaa 1982281 tatgaatagg gcaatgacgt tgcttgagca cgacttgacg aggtttggct acatttttat 1982341 agatgaatgc tgttcgaaag atatcgtacc tgtcaaaaac agcatccata cttttttgga 1982401 aacgctccaa gtcaagctgt ccatggatcg taaaagaagc ctgttcaaaa taagctctcg 1982461 actgttcatc atacagtgag tgaaaaagca tcccttcctg cataaatgac aaagggtata 1982521 tatcctgtat ttcaggttgc tgcggcatca gtgaatctcc tctcctatag tttgttgacg 1982581 gctcccatga tctcactcaa ttcatcaagc gttaagtctt catcagtgaa atcagatgcg 1982641 ctccactctt ggttttcttt gccggtacaa tgctcaatga tgttttccag agtctgttta 1982701 aaatgcctgg aaaatgtttg gattgttttt tcctcaaatt gaaacctgtt atagatgatg 1982761 tgcatgttca ggcaccccga agaaacggcg ccgctgatat ccagtgcata aggacgctcc 1982821 cagttcgggc tgatctcatt tcctggcttg atgtcagaca cctcaaaggc atttgattga 1982881 atatcctgat caaactggcc taaataatta aagctgattt ctgggctgtt tttctgagag 1982941 ccccatcttt tgctgatata tttcagcacg ccgtagcccg cgcctttatg cggtatacgg 1983001 tgcagcatat cttttgtctg tttaataagg tggcccagcc gctcttcttt gtccttatga 1983061 tcggaatctc tcatatcaag ccacacagga taaatggagg tgaaccagcc aacagttctg 1983121 ctaatatcga tgtcctcaag atatgattcc cttccatggc cctccatgct gattttaaat 1983181 tggttatttc ccgtccattt ctgcaaagca agacctaaag ctgtcagaag gatatcattc 1983241 atctccgtgc tgtaagcttt atgtgcagcc gttaatagta attctgtgtg atggcgagat 1983301 agctcaaaat caatcacttc tgtatctttg aatgtgttag atgctgcgtc attgtctttt 1983361 ggaataggct ggatgtgacg gttctcgcac tcatcccagt acgctgcttc gcgctgcacc 1983421 tggcggctta tagagtagtc agctattctt tgtgaatacg ttaaatatga atctgttttt 1983481 tgcggcagtt taatagattc tcctgagact gcctgtttgt aagctgttga aaaatcctca 1983541 aacaaaatgc gccaagaaac cgcatcaaca actaagtgat gaatcgttag aaataaatgg 1983601 tcaccattct cggttctaaa caatccagcg tgaagtaagg ggccggtttc caaacgaata 1983661 tgttcttgca tccggctggc tgcttcctca atcgtgttcc gggcttctgt taggctatcc 1983721 tttacatcaa acagttcaag tgcatatagc tcctcatctg aaagatctat ccctctgttt 1983781 atctgcactt gcctgccatc ttcatgccgg catacgattc tcagtgcatc atgatgagtc 1983841 acaaggcttt ttagtacttt tctaagcgca gcctcatcaa atcgttcagc ccggtagatc 1983901 ataacggatt ggttaaaatg atggctttcc agagattgcg agaaaaacca ctgctggata 1983961 ggtgtccaag taatctcgcc ttcgaccggg ccttggtcaa tggcgcgtac gtcttttcga 1984021 acccgggcgg acagttcacc aagagtctga tgttcaaaca tctcacgtac tgtcgtttca 1984081 aatccgcgct gcttcagtct ggcacaaacc tgcagcgctt taatagagtc tccgccaagc 1984141 ttaaagaaat tggcgcttac acccagctca tctacattaa gaagctcttc ccaaatttca 1984201 gccatcaccg tttcaatctc atttctagga ctgatatcat cagctgtata agcttgtttt 1984261 tcaggctctg gcagggcttt ctgatcgagc tttccattaa cagtcaccgg gatgctgtca 1984321 atttgtatca tacgggcagg cagcataaag tcaggcaagg cgttttttag gtaagttcgg 1984381 atgtctgata tattcgcagc ctgttgatct tttatcacca tatatgcata tatagctgtt 1984441 tgcccttgct cgtctgctct ggtaatgaca gccgcctctt taatcattgg atactgaaga 1984501 agtgccgctt ggatttcgcc taactcaata cggtgccctc tgactttcac ctgctcatca 1984561 atgcggccta agtattccag ctcgccattt gacaggcgct tagcaagatc tcctgttcgg 1984621 tataatctgt ctcccggaag ataaggattg gatacaaaac ggtcagcggt cagctcatct 1984681 ctgttgagat atccccgtgc cacaccttcg ccgcctatat acagctcccc tggaactccg 1984741 gtcggctgca ggttcatatg ggcatccatc acatgagcct gcagagtaga aagaggccgg 1984801 ccgatattgc ttttattttt tgcaatgtct gctgcggaca attttttgaa tgttacatgg 1984861 accgttgttt ctgtaatacc gtacatatta atcaaatcag tatgaggata tttttcattc 1984921 cagctttgaa gcaatccggg ctgtaaggct tcgccgccaa aaatcacata gcggatgttt 1984981 aaatgatctg tatgattttg gtcttcaagc atcaagccgt aaaaagcagt cggggtctga 1985041 ttgagtacag tgacgcgctc tttttttaac aataatcgga atgcttgggg gtcacgggct 1985101 gtttctttag agaccacgac taatgtactt ccgttcaata acgcaccgaa catctcccat 1985161 acagagaaat caaagcaata agaatgaaat aacgtccaga cgtcttcatg gttaaattca 1985221 aaaggcaggt tttgatgctt caagagactg atcacattgc ggtgctcgac aatgactccc 1985281 tttggctgac cagtcgttcc agatgtgtat atcacgtatg cgggctgatc cgttactatt 1985341 tcttcaatgt ttacatcagc cggaattgag ttgttttcac attcatcgat atacaaaata 1985401 tgcccggtgt agtctgcagg tttgtttaga ccgcgctctg tcagcagcag ttttgctccg 1985461 ctgtcattga gcataaagct aatacgctcc ttgggatatt caggatcaat cggcaaatag 1985521 gccccgccag cttttaaaat cgataaaacg ccaatgatca tatcaggtga ccgatcgagc 1985581 atcagaccga cgatatcgcc agttctgacc ccttgtttga tcagcatagc agctgcccgc 1985641 tcggcttttt cattcaggtc tcgatacgta agctgagaat ggccgcacac cactgcgata 1985701 tgctccggat actgagctac ttgcttttca aataagctta ctatgttttc atttctcgga 1985761 taagctgcat actgccccat tttttcaagg agtaacctac gctctgcagc aggaagcaat 1985821 tgcatgttcg aaattctcat ctcagtatcc gccgttaccc cttttaccaa ttcaataaaa 1985881 taggatgccc actgcgtaat ggtttcttct tcaaaaagag cagtgctgta ttcaaaacgg 1985941 cagcgtattc cactcagatg ctcctcagca tgtaatgtta aatcgaattt agatatatca 1986001 tgtttaggag tgacagacga aatcgacaga ccaggcactt cgaaccggaa atcttcactg 1986061 ctttgaagca caagcatcgc atcgaacagc gggttgcgat ttacctctcg atttgtatcg 1986121 agcttatctg ccagctcctc aaaaggataa tcctgatgct cgtaagcggt cagagccagg 1986181 tggcgaatgt catgcaaata ggagctgaac gttttgtggc cctcgggctt gctgcgcatc 1986241 gccaatgtat tgacgaacat tccgatgacg cgctccagat cagcgtgcgg tcttccggca 1986301 gcaggcgaac cgacaacaat atcctcttgc ccgcttagct tagataacaa aatagaatag 1986361 acagccagaa gaatcatata caatgttgtt cccgtttcag ccattaaacg gtgcagttca 1986421 tcagccatgt ctttatcaat gttgacttca attgttccac ccctgaaatc agggagacgc 1986481 ggccttgttt tatcaagcgg taattctagt gtaggaagac tcccgccaag ctgaccgagc 1986541 cagtaggcct cctgtttttt gtatagctct ttcgggtgct tctcttgctg ccaaacagca 1986601 aaatccttat aatgcaggtt taaagctggc aactcttttc cgcaatataa gtcagtaaat 1986661 tcttggacaa gagtgctcat cgagacaccg tcggcaataa tatggtgcat atcgagcagc 1986721 aaaaagccgc gattattgcc cattgtaatg acacatgctc taaaaagcgg accggatgat 1986781 agataaaacg gtttgataaa ggtctcgatt gcagactcaa gcatttgttc tgattccatt 1986841 tcaagctctt ttagatcaaa agccatctct ggataaatga tctgcacagg ctcgtctctg 1986901 tcaagcacaa aaacagtccg taatgcttca tgccgattca caagttctgt gagaacgctt 1986961 ctcaaccgct ggcgattcag atttccgcgt aattcaagta cagctggcat gttgtagcct 1987021 gtgctgtcat ctgccagctg atgaagagca tataatcgtt tttgcgagaa agacagcgga 1987081 tagacatctc tttgatccgc aggttcaatc tgtgtaaaag cgtgttcttt taagctcatc 1987141 aatttgaccg ccatgctttc aaccgtcgga taagaaaaca cctcactgag cggcagctcg 1987201 acattaagct ttttatgtat tcttgatacc agtgcggccg cttttaagga ctgtccgcct 1987261 aactgaaaga aatcatcacg aatgccgatg tgctgtttat tcagcacatc ttcccaaata 1987321 tgtgcgagat cagcttcgat taaggttcgg ggcgccatat atgtgacact cgtattgttt 1987381 tctggttcag gaagcgcaaa cctgtcaagc ttgccgctgg atgttaatgg catctggctg 1987441 atgttgataa tacttgctgg gatcatatag gacggcaatg tcccggcaag atgctgatac 1987501 aaatctggga ggctgtttcc cttttccgga acgatataag caacgagctc cttttcctca 1987561 gcagaaacat cacgggccag taccgctgct tcttttaccc ccggtgcttg tcgaagaact 1987621 gtttcaatct ctctcagttc aatacgataa cccctaattt tcacttgatc atcaaaacgt 1987681 ccaatatatt caatcgttcc atcaggcaaa aagcggcctg catcacctgt tcggtataaa 1987741 cgctcccctt caaggaatgg atgatcggag aatgctttct gtgtcagctc ttgctgtttg 1987801 tagtatcctc tcgcaagacc cgcgccggaa atacacagtt cacccgccgc gccgatcggc 1987861 tgcatttgat ttccgtgcaa aacaaatact tttgtgtttc tgatcgggtg tccgatcgtg 1987921 atcctctctt ttttattcag atgccgcaat attgttgttg ccacactgtt ttctgtgggc 1987981 ccgtattcat ttgccagttc agcagaagga caaattattt gattcaactc aagcagatca 1988041 ggcgtgaccg cttcacccgc aaatgtcaca atacgaagac tttttgcatc gtcagcagtc 1988101 atcacttcca ataacaccct gtacagggaa ggaacaatga tcatgtggct gaccttataa 1988161 cgggctattt ttcgcttaag ggccagcaca tccttcgctt cgtcatctgt tgtcagcagt 1988221 acgcacgcac cagataaaag cggggtaaat aagctcgtta cacagccgtc aaacacgtac 1988281 gaaaacaaat ggagggatat atcctgttcg gtcatgctat actcttcccg tctccattgc 1988341 aatgtattgg caataccgtg atgatcaact aaaacccctt tagggcgccc cgtcgttccc 1988401 gacgtataga tcaagtaggc tagatcacct ggcggcatat ttggcgcttc tgtttggtaa 1988461 ctttctgtat gttctatcgt tatcgtattt ccttcatagg acggagggat caaggaaata 1988521 aggtcttctt ctatcagcaa ttgagccgct tgactgtcct tcagaagaaa agaaagacgt 1988581 tctgctggaa aatgtggatc aagcggcata taagcgccgc ctgctttcca aatcccaagc 1988641 agagctgcag gcatttccat tgaccggccc atcattacag caacgatatc cccagatcca 1988701 acgccttttt ctatcagggc gtgcgcaatc tgattggctc ttacttgtaa ctggcgatag 1988761 gtccagcact cgtttcccat tttcaatgca gcagcttcag gtgttttgtg agcttgttcc 1988821 tcaaacaatt ggggtatcgt tttgttcaca taaggacgct cagtttcgtt aaacaattgg 1988881 ataacctgtt gctcctccgg cggcacgata ttgatgtcac tgacggcaac atcgggattt 1988941 gtcaaaatgc aatccagtgc ttgctttaga tgcccctgaa tcctcagcat ctcctcccgc 1989001 tcgtaaacgt ctgcgttgta gctgaatttg atataaaatg attctcccgg aacgataacg 1989061 atattaaagt cgtaattggt ttgttccgac attgaaatgt cactcagctt cagagcgcct 1989121 tcgtcatttt cactctccac gcttaatgcc tgatgaagct gtacagggta attttcaaaa 1989181 acaaaaatat gatcgatcaa cccttgcttc aatggactat ggttttgaat ctcataaagc 1989241 ggataatacc catgctgttc agatgataaa atatcctcct gcacggcttt gaccagcgaa 1989301 gaaaatgtta tgccttccgc agatcggatt cgcactggaa cagtattgat aaacaaaccg 1989361 accattgatt caatcccgtc aatcgctgac gggcgtcccg aaatgacgga gccaaaaacg 1989421 gcatcatctg cagcattata tcgatggagc agcacgcccc aaatactcat aaacagcgtg 1989481 tttaatgtca ctccccagtt ttgggcagcc tctgtcagtt tctcaaccat atccggcgct 1989541 aatgaaaagc tgacctggtc ggctttataa ttcccgtctg ccgtgcggcg ctttattcgg 1989601 ggaatagaag cagtattgcc gtactccttc aaatattcgc tccagtaggc agcagtctct 1989661 tcttgatctt gttctccgag ccattcaata taacggctgt acggcaccgt gctgccaagc 1989721 tgtacaggtg agttattttt gagcgaatca tacatgctga aaaactcttt aagaataatg 1989781 ccgagacacc acccatccat gatgatatgg tgatgtgtcc agacacatgt atattggctg 1989841 tctcctctat caaaaagggc aagacgcatt aaaggatctt tttgcaaatc aaatcctttt 1989901 tcccgatcct tagtcataaa agcatcaatc agcgtctgct gttcttgatc agccaggcga 1989961 gaaatatctt ctctatatac tgtcaattca cggtttgata gaactacctg ctgcggacct 1990021 gtaagatctg gtacttcttt aatgaaaatc gttctgaaaa tatcatatct agaaacaaga 1990081 aggtttaagc tcttttgaaa cgagtcgacg catagattcc ctgtgatcgt aaacgaggtc 1990141 tgttcgatat atgctttcga gctgaaatcc attagtgaat gaaacagcat tccttcctgc 1990201 atgtgcgata acggataaat atcttgaatt tgtgccgatt gtgccatcaa ttccacacac 1990261 cttttcaaaa gttaaagatc tttcacgaga tcttcgatgc tagataatgc agacaacgtt 1990321 aattctttat tgctgaaatc gctcaatgtt ttttcgcgtg cttttttctg cgaacaatgc 1990381 tcaatcgtct cgataagatg cctgtgaaaa cgatccataa agcactcaat tgagtgtttg 1990441 ctgaacactt gggtgtatac cgcttttacg tgaagccgtc cgtccgtaat gagagcattg 1990501 atgtccagct catactctcg ttctctctca cccgctattt cgtaacgggg ctggtaatat 1990561 gataattgaa acgtttcaac ttccttctct tcgctaaatt gaccgagata attaaagctg 1990621 acctcaggct ctttatgccg cagttctcct atgtgtgtta acaatccgta tccagttcct 1990681 ttgttcggta ctcttctcag catatctttt gtcgtcttaa ttcggtatgc gagctgatcc 1990741 tcgaaaggct cgggaatacc catgtctagc agaataggat aaatggaggt aaaccatcca 1990801 actgtccttg aaatatcaat gtttggcaca tgcccttctc taccgtgtcc ctcagtgctg 1990861 atcacgattt ggtcatgccc agtccattca gaaagcgcca ttcctaaagc cgtaagcaaa 1990921 agttcgttgg catcagtacc ataggcttgc tgggtttcaa acagcaattt ttcagtccag 1990981 tccccggata gtacaaacgc tgctgcgtcg ctgttcattt ggagtttgtc tggcacattt 1991041 tctatgtcct taggaagaaa agcagtgtga gcgtctaaaa tcgtttgcca atacgttttc 1991101 tctgaaagca attgtttact ttcagctatt tgggtaagac catcggcgta ggataaataa 1991161 gaatccgttt ttggcggtaa ttggatttct ttcttttcta aagcctgttg atatgctgca 1991221 gctaaatcct caagcagaat tctccaagaa acgccatcta tcacaagatg atgaagtgca 1991281 atcagcaaat gatccccttc tgccgtttta aacaaacctg cttgcagtaa gggccctttt 1991341 tctacattca ttttgctttg aatgacggtt tcctcagcgg caagtttttc atcaagatga 1991401 gccctttcca gcgatgcttt tgtccaatct gaaatataaa ggccaaacag ttcatgatcc 1991461 ttgtgattga ttccgcgatt aaactgaatg acatggccgt tttggtcacg ttggaaaatc 1991521 atgcgaatgg catcatgatg ctcggttatt ttacgcagcg ctagatgaag cgcgttagca 1991581 ttgaatcctt tttcactgaa aagcatgacg gactggttgt aatgatagtg aaaagcatgt 1991641 acctgtccga aaaatcttcg ctgaatcggg gtgagttcag cttcaccttc cgcaggtccc 1991701 tggtccgctt gagatgccaa tggtgtgata tgtccgcata gttcctgaat cgttgaataa 1991761 cggaataagt cgcgtattgt catgctccag ccttcagctg ccagacgtgc tgccacttgt 1991821 aatgctttaa ttgagtctcc gccaagctca aaaaaggaat cgtgaatgcc gactcgtgac 1991881 atgctcagta catcttccca tatatacgcc atcgtttttt gtaagtcgtt aactggtgcg 1991941 gtatatggac gcgataacac attatttgga gccggcaagg catttctgtc cagctttccg 1992001 tttagggtca gcggcatgtt tactaaagga atcagatatg caggaatcat atacgctggc 1992061 agttcctttg ttaaagcagc acggagagca ttcgtattga cgtctgaagg cacaatatat 1992121 gctgccaaac cagcctgtcc atttttatca tgctgaacgg caacagcagc ttctctgaca 1992181 agccccgttt gaagcagaac actttcaatt tcttctgttt caattctgta tccatttatc 1992241 tttacttgat aatccattcg gccaagaagc cggatcgttc cgtttggaag ccagcatgct 1992301 cgatcaccgg ttctgtacag cctttctcca gagacaaatg gattttctgt aaatttcatt 1992361 tgcgttaagt caggtttatg atgatagcct ttcgcaacac ctgccccgcc gatgcacagc 1992421 tcgccggcaa caccgatcgg ctgaatttga tcagtctggc tgagtacgta catgtgtaca 1992481 ttcggcagcg ggctgccgat tggtacgtta tctcccgtac actctccacc catactggtt 1992541 tcatagaaac tcgaatcaat ggttgcctct gtgacaccat agctattaat gatgcgcatg 1992601 ctttggccaa agcgatctgt caatgttttg aaatcttgag ctttcaccat gtcggaacca 1992661 agaatcagta tgtctaagtc aggaagcttg aactggttac ggtatacata ctccatcacc 1992721 gggataatga gagccggtgt cgactccatc accgtgattc tctgagattt aatgatttta 1992781 tatatttcag caggttccag ccgtgtttca tctgggcaaa cgattagagt cccgccgttg 1992841 gtcaatgttc tcgccaaatc tcctgagaag acatcgaatg aaaagctcgc gatttgaagc 1992901 agtctgacag gcttccgatc cagttcataa atttgacgcc aagcaagagc agcatgagta 1992961 aagttctgat aggtgacaat aacaccttta ggcgcacccg tcgttcctga cgtataaatg 1993021 atatataccg gctcttcagg agcaggagat aagttaaggt tgcagttact ttcttcaaaa 1993081 gagccctcat cgtcaaggaa gatgtgagac atctcagatt caggcgagtt cgaaatcaaa 1993141 tgcttcaact ctctctgtaa aagaagaata tctgccccgc tatcacgaag aatgtattca 1993201 atacgagctt ttggataatg tgcatcgatt gggatataca ctccgccagc tttcatcact 1993261 gccagaactc caacaattgc atcgatggac cgcttggcta aaacagccac agttggcttc 1993321 ggtccttttc tgttttgcaa tgttcgtgcc agacgattgg ctctttcatt tagaaggcga 1993381 tagctaatct ctgtttcgtt atcaataaca gctatatgtt ctggattttc ttcagctttc 1993441 gcttcaaata tgcgatgaaa aggaatatct ttttgagcaa attcaacttg agttttgtta 1993501 aattcaaaga ctattttttg tttttcttta tcactaagta tgtttatttg tgcaaggctt 1993561 gtttcaggag ttgaaagtgc ctcatgcaga aattcgataa aatgatcagc ccagcgttca 1993621 atcgtagctt tcaggaatac ttctgtacta aattccattt cgcagcaaat agatccactt 1993681 atttccgtag ctattaatgt gatatcaaat aaggaaatgt gatgtgcgaa attggcaggc 1993741 cggactttta tttctctcag atctatgtct tgtttttcca cattttgaag gataaacatc 1993801 gcatcaaaca ctgggttccg gctcatatct cgtgtcaatt caagcttatc gacaagctct 1993861 tcgaacgggt aatcctggtg ctcaaaggct tccaatgctg tctcacgcac ttcctgcaaa 1993921 tactgtacga atggcttccc gccctccggg cgcgtccgaa gcgccagcgt gttcacaaac 1993981 atgccgagta tcggctcaag atccttgtgc ggccggccgg caattggcga gccgacgatg 1994041 atatcttcct gtccgcttaa gcgtgacaag aacgcggtgt aagccgcaag aagcaccatg 1994101 tacagtgtgc ttccgttttc acgtgccagc ttgtgaaggc ctgatgcaac ctcttgatcc 1994161 agcgtaaatg agaccttgtc acccgcgaag cttcgcaccg gcgggcgggc atgatcagcc 1994221 ggaagatcca gcacaggcag ctcgccctcg agctgcttca gccagtacgc ctcttgcgtt 1994281 ttgtacgcgt ctcctgtttt gaatccttct cgccatacgg cataatcttt atattgaatg 1994341 cgcagtgccg gaagattccg attattgtac agctcgccga attcccgaat cagaatgttg 1994401 acggaaacac cgtctgaaat gatgtgatgc atatcaacca gcaacaggtg ccgctcatct 1994461 gatatcttta cgatttgggc acggaacagc ggcgcttggc tgagatcaaa cggtttgata 1994521 aatgcggctg cggcctcctg ttcggttcgt tcgccgagaa ctgtagtctg taacgtaaac 1994581 ggcacctcgt catggatgcg ctgcaccgga tcgcctcctg cgtcctgttc gaaggaggtc 1994641 cgaagcgact cgtggcgctt gatcagctct ttgaaagctc tctccatcct ttcagggttg 1994701 agcttccctt cgagctctaa cacagccggc atattgtagc ctgtccctcc gtcctccagc 1994761 tgctgaagga cataaatccg cttttgggca gaggaaaccg gataggtttc ctgtttttca 1994821 gcgggcttaa tcgcttcata tggactgtcc gttccttcac ggataacggt agccagtcct 1994881 tctactgtcg gatgggcaaa cacatctttt agcggcacct gtacatcgaa ttctttggcg 1994941 atccgtgaga caagcgccgt tgcttttaag gaatgtcccc cgcggtcaaa aaagttgtcg 1995001 tgaatcccga cagggccatt tttcagcacg tcctcccaca gctgagaaag cttcatctca 1995061 gtcacgtttc tcggcgccgt gtaggtctcc gcatctgccg ctccgccagg agctggcagg 1995121 gcgtttcggt cgagctttcc gcttggcgta accggccact gttccatctc tatcatatag 1995181 gctgggacca tgtagcccgg caacagtctc tcaagctgtg cacgcacttc gtttctttgg 1995241 agcccttcta cataagcgca taattccggc tccccgctgt ctgtccgtac ggtaacagcc 1995301 gcctctctta cgccttctat gcttcttagt gccgcttcaa tttctcccgg ctcaatccgg 1995361 tagccgcgga tttttacctg atcatccgtg cgcccgagga attcaacatt cccgtcaggg 1995421 agccagcgcg ccacatcccc ggttttgtac atgcgttccc ccgggtaaaa cgggtcttca 1995481 agaaaacgct cctccgttaa tgccggccga ttcaaataac ctctggcaac acccgctccg 1995541 gcaatgtaca gttcgccggc gacaccggaa ggctgtacgg ctaaatgcgg atctaaaaca 1995601 tacaaacgcg caccaggtac gggcttccca atcggaatcc gcaaacgatc cctgtcccgt 1995661 tctggatcca atacgtaaaa tgccgcgtct accgttgctt ctgtcggccc gtaaccatgg 1995721 attaatgata cctgcggcaa tacagaagca aaacgggctg ccgtacgcgg cgcaagcggt 1995781 tcacctccgg cgaatacacg ctttaggctt gtcctgtcac tcagcctttc gatttccgct 1995841 tgatcgagaa agctgttcag catagccgga ataaaatgag ccgttgtcac gttttcctga 1995901 tgaatggctt gtacgatcaa tgcggagtct ttctcccagc cgggcggaag cagatacgcc 1995961 gaagcaccgg aaagcgacca ccaaaacagc tgccacacag acgcatcaaa ggaaaaagag 1996021 gttttcacca tgacaatgtc atcttccgaa agcggaaact ggtgctgcat gccggtcaga 1996081 aaggaaacag cctgacggtg ctcaacggcc actcctttcg gctgcccggt agagcccgat 1996141 gtatagatga cataggcgag agatccgccg tcagcaggag taaactcatg gttttctgct 1996201 ttttcgctcg caagagatgt catgtccact tcaagcgttt cgccagaaaa gtttggtgcg 1996261 gagcatcccg gctgtgtcag caagagcgat gccccgctgt ctttcagcat gtagctcagc 1996321 cgctcctttg gatacgcagg atcaagcggc aaatacgccc cgccggcctt caatacagca 1996381 aggacagcga tcagcatgtc aggtgagcgt tcagacagga caccgacgat actttcgttt 1996441 gtgacgccgc gtgccgcaag gtgcgcagcc agccggctgg cgtacatatc aagctcagcg 1996501 tatgtcagcg aaccgcctga aaagcgaatg gccagccgct ccggtgtgaa agctgcctgt 1996561 cgctcaaaca gcccatgcag ggtgaaagct ttaggcgaaa cagcttccgt cttgttaaac 1996621 tcatacaaca atttttgctt ttctcttgta ttcgtcatat ctaattctct tataaagctg 1996681 tgcggatgtt taagggcgtt ttccagtatg gtaagcagat gagattgtat tcgtttaata 1996741 tcctcaagag aaaacaaggt attttgatag tcgaaattta attgaatggt tccattgtct 1996801 atccgttctt gtatttgaac tgaaagttcg ttcgcggtgt atccgctgaa ataaagcgct 1996861 gtttcatagt caaaatcatc tgcattgtgc cactgaagtg gctgatactg catagatata 1996921 ccgataaggt tgtgtaaatc cttctgttca tttcttaatt catttacaag caaattataa 1996981 ggaaaccgtt gatgacgcat aacagaaagc tgttccctgc ctattgtgcg gacaaaggaa 1997041 agaaaatctg tgtcaggatc aaccgttatt ctgattggaa gggaactaac gaacatgccg 1997101 agcatttctt tttcagcctt tgaacctctg ttgccatagt aggtgccaat ggcaagatct 1997161 tttttagaag tgattcggct gatgcatatg taaaatgaag ccataaataa ggaaatgata 1997221 ttgatcttgt gttcttcgca gaagattcga atcgtttgct ctagatcagg tgaaagaatg 1997281 atggtgtctc tggatgcaga tgtgctctgt ttttgtaagg acgtctggtc ggctaacgag 1997341 tggtattcca acgggtgctc aaaggtttgc gtccaaaata aacggtcctt tgcaaaccgt 1997401 ggagattgta gatattgact ctctttttcg atgtagctca agtaagaagg ttccggctga 1997461 tcaggtaaag gatctttctt tttcattttt tgataaagat ctataatttg atttcccatc 1997521 acatttaaag agattccatc cattatgata tgatggaatt tcgcaaatag ccaaacttca 1997581 tgagagtcaa ttctaaggag gtaaaattga aaaagaggcg agttgaacag tttaaatgga 1997641 atgctcgctt gatcctgaat ccattgctct atttctatca tttcaacatt tgaaaaatca 1997701 attattctaa gtggataata tttatattca gtaaggtgca atcgaggctc aagctcttct 1997761 ccttctaaca gctgaaatct aatggcgtcg ttgcgggaga tggaatgatt cagtgctccc 1997821 tccagagtat caagctcaat attgccttta aatttcacac aagctgtaag attgcaaatg 1997881 ctggtatctg gctccagcag ttcggtaaac cacactctcc tttgggcatg ggttaaagaa 1997941 taagtatgtt cgctcaacgg attccctcca gttctcataa taagaggata agaaaatgta 1998001 gaaaaaagca gaaaaatgac aataaaagaa attatatgac tatataatcc atatatgcac 1998061 tatattaacg gatatttttt aaagtacaat aaaaaacatt aaatttttat aacatttttt 1998121 ttgaatatag tattatttct ttatttttcg tttctttttt tatcaaattt ccggatataa 1998181 agtgataaaa gtattgtttt acataaggtc ttatacacta ctttttaatc ggactaattt 1998241 tcttttgtgc atcattcttc taattgttgg aaggttcgac aaagcgttat tacagacata 1998301 aaaaaacctg ttttctcttg gaaaacaggt ctcccgctat tattgatttg ccaaaatgac 1998361 agcgatttga tcctcaatat cttttccatc ctcttcatca atcaatccat ttagaagaat 1998421 agagaaaaca agtttttttc cgctctttgt ttctgcgtac cccgatagag agcttaccgt 1998481 actgagcgat ccggtttttg ctcttacttt tccttgtgca ggagtgcctt tcatgcggtt 1998541 tctcagcgtt ccgcccacca ttctgtcagg attccccgca acaggtaaag aatttagata 1998601 agccgagaac caactctgat cctgaatgtc atataacagc tgtgaaagtt gatctgagga 1998661 tacagcatca atatgtgaga ttcctgatcc gtcccttaag acgagtgatt tagaatcaac 1998721 accaaattcc ggaagcgtac tgtttaacac ttcgagcccc ttttcccagc tcccttctcc 1998781 ttttttcact ttccccatct cttttacgag cacttcggca tgtccgttat tacttaattt 1998841 catgaacggc acaaaaagtt tcgataaagg cattgagcga tgagagagca gcacatctga 1998901 agaactaggt gcttcacccg tcttgatgtc ccctttcaca gtaatacctt gtttttttag 1998961 tgactgctta aataaatcta aggcatatcc ggcaggctcc cagacagaaa tccattcctt 1999021 tgtcttgttt gcgtcaaccg gtacgctccc ttcaattgta atcgtgtttg ttccatgctc 1999081 tctttcgatt gtgaggtctt tctctgaacc ggcagcagtc gttttagcat cgttctttat 1999141 cgttatataa tcggttttcg gagagacaga cacggcaggc tcttcccctt ctttttgatt 1999201 tggggtgacc tcaacaatca cagtgcctgc atcatagtct tcgtttggag acgctgttag 1999261 agcggagatt ggcgcgccat aatatgtgta ttcatcgctc caaggcatat caggtgataa 1999321 tcgcatgtca tcatgccacg tatcatcacc gatcagattg cctttaatta cttttacgcc 1999381 ggaatgtttc aatatctcag ccattttgtc aaaatcagat ggtaaaagtg tcggatcgcc 1999441 tttccctttc aaataaaggt taccattcag ctttttccct ttcagtgttc catccgtccg 1999501 gacctcggtt gtaaaagaat agttctcgcc aaggacagaa agtgccgcgg ccgctgtcaa 1999561 aagctttaga gaagaggcag gcctcattcg ggtgtctcct gaatgttcat atagaacagc 1999621 acctgtttcc gcagagcgaa cggtgatgcc ggccattgcg ccttcgaggg caggatgatc 1999681 agctaaaatc ttatcgatct gcccggaaag tgcatcttgt ttttcagcgg caagcgcagc 1999741 ctgatgcata taaggcaccg aagcaacgac gaaaagcagt aaaacagcaa cataaagctt 1999801 tatgcttttt ttcattaatt tccccgcctc tctgcgcttc atcattggct attgatgatt 1999861 cagttcaatg gtgatactgc ttttagctgt cgtttcttct cccggctcca gcacttgtaa 1999921 accagtgagt gacgaaggta aatcaagatt cactgcgttt gtcacccatg tgtaaggctc 1999981 agggcataaa tacccttgtt ttccgtccgc attgtataca acccaatgtt taaactgttc 2000041 atctgcctta taaataatgc tgatatgtgc atgctgatga taaatgactg cctggttttc 2000101 tccgcccctc ttctgataag aagataaaaa gacatcatcc agctgcttgt ggcgcaaatc 2000161 cattccttca tgcaaagctt ctttatacgg gacatccatc agcttcccgg tcggcagcag 2000221 gcgttcatcc aactcccatt gctgatctgc tgtcagggag aataacgagc tttctgccgg 2000281 aaatataaat gtagtatgat aaccaattcc ccaaggaaac gcttcctttc ctttgttcat 2000341 gaccgtcgca tgtttaaata gggtattctc cttgatcgtg tatgtcatcc gaacgacggc 2000401 atgatgagga aattgcttct gcacatgggg aagctcagaa agatcaattt ctgtttcaac 2000461 aatcactcct tcatcagttt gcttcgtggt cacgacattc cacttttcat ggtaaagaaa 2000521 cccgtgaaga tggttgtgtt tatccttctc gttgatatca aaatgatacg ttctgccccg 2000581 gaaactgaat gtaccgtcac ttatgcggtt aggcgggaac aggattggaa tgccatacaa 2000641 tgttggtgtg tcgtgaaaac tttctgctgt ttccggttca cgcaaaagct ggacatttgt 2000701 tgttttgtcc acgagagaaa tgacgttgct cccccactca gggacaacaa tcatttctag 2000761 atgttcgttg cccgctttga tggccggcgt tcccaaatac gtgattttct caataaagtt 2000821 tgccatgttt actcaacctc tccttgattc attgctagta taagaattca atgtactgta 2000881 ccatatttcc tccattttat attttcccct atcaaataaa aaaacaccgt tcaaacttat 2000941 gaacggtgtg attcggaggc tattggatga gacgtgtgat ttgtttcttt ttccagacga 2001001 attgataata cccataaatc aacagcaagc tgacggcaaa cgcagctgga taaccaaccc 2001061 agacgccgag tatttcaagc tttgtatagt gagaaaggac gaaagcgaca ggcacctcta 2001121 ctccccagat tgcaaaaata ctgatgacgg tcggccataa aactgttccg cttgcccgca 2001181 tcgttgcaga aataatttgg gcatttccaa acagcaaata gctccacagt gtaatcatca 2001241 aaagacggtg cgcaatgtaa agcgtctctt gctcggttaa aaataacgat aaaatctgat 2001301 gtgaaaaaac atagatcaga atgatcagta cgccgccaat gatataattc agccaaatcc 2001361 caacgcgaat gacctgcttt aagcggtcaa actcgtttgc tccgatcgat tgcgcagcga 2001421 aaatagaaac cgcaatacca aggctgacgg ccggcatctg tacatagctg gccacctggt 2001481 tgaccactcc gtatgcagct gttgcattag agccgtaatg attgacgaat gaaataaccg 2001541 ctatctctga taatgagaca agaatcatat tgatgcttgc tgggacccca agacgcagca 2001601 ggagaaccag cagttcctta tccattttca aataacgacg cactgtttta tcaaattgca 2001661 gcgggtgttt tcgctttcgt aaatacacca ttaacacgag aaaagtcgca atcgtggaaa 2001721 tgacagttgc atatgccgag ccgtatatgc ccagtttcgg aaaaccaaac atgccaagga 2001781 ttaaaacagg caaaagcgcg atgttgatga ccgtgctcac aatcagcgta taaaacggtg 2001841 tcttggaatc tcctgttccg cgcaaaaagg tagtatatgc aaaatataaa aacataaacg 2001901 gcatagcata aaataaaata cgtgcatagt tagcgctgac atgaatgaca ttttcaggtg 2001961 ttcccattaa acgaaggata tccagggtga aaatactgcc gataacggct aacacaacgc 2002021 ctaataaaaa tgtaaacgtg agtgtcgtcc cgacaacagc ctttagccgt tcctcatttt 2002081 tcgctccgta agcttgtcct atcagaatcg aacttcctga accgatccca atcgtaaatg 2002141 agattaaaag aaaaaataac gggaaaaagg atgatacagc tgccactgca tcaacaccga 2002201 gccatctgcc tacagccatc atcccgacta gctggccgac tgattgcagc acattgctca 2002261 gcagaagcgg cactaaaaag agtgacatcg accgccaaac tgatggtttg cttttctttt 2002321 gagttacaag aggttcttgt gatgtttcca tattaaagga ctcctttatt tgaaatcgtt 2002381 tttaaacatg ccctcatttt ttgacaaaaa caggatatgt aacatgttat tattcatcac 2002441 tgcacttatg aaacccttcc cgattcttct aattttacac atctttttag cttatgaaga 2002501 ataaactagc aagtaatggc gtattttttg tgagtaaaag aataaaaaat aatttatgca 2002561 aaagtattgt aatctatccg taattattgt aacatttgta acataagaga aagagatttt 2002621 gaaggagaga gcgataatga aaaaatgtct tctatttcta acaaccattg cacttattct 2002681 gtcattaagc acaaatgcat ttgcgaaaaa tacatcaggc gatttatcac aaaaacaagc 2002741 attacagttg gcattatccg ctagagaaca tttttggaac accatgagcg gccacaatcc 2002801 gaaggtgaaa aaagcagttt gcccatcagg cacattcgag tatcaaaatc ttcaatatgt 2002861 atacatgtgc agtgatctag gcactaaagc aaaagcggtg aattatttaa ctcctatttt 2002921 tacaaaaaca gcaatcgaaa aaggctttaa agattatcat ttcactgttt caaaaggaaa 2002981 acttgctgtt ccaatcggtg acggagacaa tcttttgaat tggaaaaaat caactgctaa 2003041 actgatctct aaaaaaggca gcacaatcac atacgaattt actgtcccta cattagacgg 2003101 atccccttct gcaaaacgga aagtgacatt tgtgaaagaa aataaaaaat ggaaagtcaa 2003161 tcaatttgac gcagttatat aagaaaaacg cccggtataa gcgggcgttt tttatttggt 2003221 ttgcataaag aaagacaaca ggcgaaaagt gcctgttgtc tttttgtgaa tataacgctc 2003281 taggagagat tcgaactccc gacctgcagt ttaggaaact gctgcactat ccgctgtgct 2003341 actagagctt ttggtattta tatagtagct ctgatgatca atattttcaa gcgatttgta 2003401 ttaaagccct ccaaaaacct tatatgcggc tcttgtcgta tcttcatcaa taccgatata 2003461 ccgcattgta attgatggtg atgaatgatt cagtattctc tgcagctcgg cgatgtcttt 2003521 cgttcgctga taaaaatgat agccaaacgt tttccggagt gtatgcgtcc ctatctcctc 2003581 aagtccgcac gctgcagcgg cctctcttaa aattctgtag gcctgaatgc gggaaatcgg 2003641 cttcctggtc cgcactgatt taaaaagata ttcgttttcc ttcatgtctt tcgtatactc 2003701 gtatatttcc tgtttcagcg attctaaaat aagaatcttt cttttctttt tcgttttgct 2003761 ttcagtcgcc cataaatgat ctttattttg aacgtccttc acttgcagcg gcagaatatc 2003821 agaaatacgg agcgcgctgt tgatgccgaa aataaacaga aaataatccc gcttgttttt 2003881 gttaagcaaa tactgtttga cttcttggat tttctctaga ctgcgaatcg gctgtacaat 2003941 atgcatcaaa aaactcctta aaaaccgtta tgtaacattt tgaggtctat gttactatta 2004001 tagctgaaaa acgttgaatg tcaaagtgcg gcggcgttta tgtaacataa tatacatagt 2004061 gttacataag cttttaaaaa agcttcttcc aaccttcacc ctataaaata agctttaaag 2004121 cctcttataa agcttttaac ctcttggata cttatccccc tactaatcat caaaaaacct 2004181 cttaaaatga aatctgacac tcccaatttt ctggagcttc cgcaaaaata tacaaaaaaa 2004241 gacacaattt caaattgtgt cctaatcctc atcctttaca tcaatatctt ccgggatcgg 2004301 ttcatttaat atttcctgca caagtgcttt gtaattctcc agctgttcga gatgcgtttt 2004361 gaactgttcc ttataaatca aaaattgctc cccgtcatga acggctctga ttttcccttc 2004421 gagcaccaag cttttaatat aatcctctga aagatttgta tattctgctg tttcttcaat 2004481 cgttaaatac atatagcagt cccttcttaa tccgtatgct gattctaata tagcacatgg 2004541 ctcatatcaa tataatcaat tctgcacaga aaaacggcat tatgcactat ataatatacc 2004601 atttgtcact tgtgaaaacg ctgtaatttt tttacgctaa gattgtaaca atacagcttc 2004661 atataggagg gagaacatga aaagaacgtg gaacgtctgt ttaacagctc tgcttagtgt 2004721 tctgttagtc gctggaagtg tcccttttca cgcggaagct aaaaaaccgc ccaaaagcta 2004781 cgatgagtac aaacaagtag atgttggaaa agacggcatg gttgcgaccg cacatcctct 2004841 tgcttctgaa atcggtgctg atgtgctgaa aaaaggagga aatgctattg acgcagcggt 2004901 tgccattcaa tttgcactca atgtaacaga gccgatgatg tcaggtattg gcggcggcgg 2004961 ttttatgatg gtgtatgacg gaaaaacgaa ggatacaacg ataatcgaca gccgtgagcg 2005021 tgctccagca ggcgcaactc ctgatatgtt tctggacgaa aacggcaaag caattccttt 2005081 ctctgaacgt gtaacaaaag gtactgccgt tggtgttcca ggcactctga aagggctgga 2005141 agaagccttg gataaatggg gaacccgttc gatgaagcaa ttaattaccc cttctattaa 2005201 actcgctgaa aaaggctttc cgattgattc ggtgttggca gaggccattt ctgattatca 2005261 ggaaaagctt tcacggactg ccgcaaaaga tgtattttta ccaaatggcg aaccgcttaa 2005321 agaaggagat acccttattc aaaaggattt ggctaaaaca tttaagctta ttcgctccaa 2005381 aggcactgac gctttttata aaggaaaatt cgccaagacg ctttctgaca ctgtccagga 2005441 tttcggcgga tcaatgacag aaaaagattt agaaaattac gacattacaa ttgatgaacc 2005501 gatttgggga gattatcaag gctatcaaat cgctactact cctcctccaa gctccggcgg 2005561 tattttctta ttgcaaatgc tgaaaatcct tgatcatttt aacctttcac aatacgatgt 2005621 ccgctcatgg gaaaaatatc agctgcttgc tgaaacgatg catttgtcat atgccgaccg 2005681 tgcgtcttac gcaggtgatc ccgaatttgt aaatgttcct ctcaaaggcc tgcttcaccc 2005741 cgattatatt aaagaacgcc agcaattaat caacctagat caagtgaata aaaaaccgaa 2005801 agccggtgac ccttggaaat accaagaagg atcagcaaac tataaacaag ttgaacagcc 2005861 gaaagacaaa gtagaaggcc aaacaaccca ctttacagtt gctgaccgtt ggggaaatgt 2005921 tgtttcttat acaacaacaa tcgaacagct attcggaacg ggtattatgg tccctgatta 2005981 cggtgttatt ttaaacaatg aattaacgga ttttgatgcg ataccaggcg gagctaacga 2006041 agtacagcca aacaaacggc ctttaagcag catgaccccg acgattttat ttaaggatga 2006101 caagcctgtc ctcacggttg gatctcctgg cggggccaca attatttcat ccgttttgca 2006161 aaccattctc taccacattg aatatggtat ggaattaaaa gcagctgttg aagagccgag 2006221 aatttacaca aacagcatga gctcttaccg ttacgaagac ggagttccta aagatgtcct 2006281 cagcaagcta aacggcatgg gccacaaatt cggcacaagt ccggtggata tcggaaacgt 2006341 gcaaagtata tcgatcgacc atgaaaacgg cacctttaaa ggtgtagctg attcaagcag 2006401 aaacggcgcg gcgatcggca ttaatttaaa acgtaaataa ataaaaaact gtactcgctt 2006461 caaatgagta cagttttttc atgcagatct ttaaaataaa aactgacaaa cgtctttatt 2006521 ctgctaatgc acgtctatct tcatcttttc atttcgttta tctcatcaag aaatgtctga 2006581 aacgcactcg taataaaaaa gtctttcctg tatataaaga cgatctctaa gtcttgatat 2006641 gatggtggca gctgatgaat ccatacattt gtacgatgct cggagccgtc aacagcggac 2006701 tttgggagca gcgccgtacc catcccggcg gaaacacctt ttataatagc ctccaatgtg 2006761 ccaaactcta tgattttttg attgtgtatg cctgcttcct ctagtaatct tttgaccctg 2006821 tcacgatgag aacagccagc cccaaaaaag agcatcggct gctgaagcat gtcttctgcc 2006881 gtcccttctc gtgatgaaat caaaactaat tcatcatggg agacatggag ttgtctaact 2006941 gcagcgtgtt caaccggccc atatacaaaa gcgccatcaa ctttatgatc aagaacctgt 2007001 tgaatcaaat gatgcgtatc agctgtgttc actgataaat ccacttcagg aaaacgcctg 2007061 aggaaggatg ctgcatgctc aggcagatgc gttaccgcca ttgtttccag tgatccgatc 2007121 cgcaaaggcc cttttggttg cctgctcatt cgggtcgatt tttcagcttg gtctaacagc 2007181 gataatactt gatctgcata ttgtaaaaga ttttctcctg cagcagtcag cttcattccc 2007241 cgattcgttc gatgaaaaag cctgatattc aaatcttcct caaggttatg cactctggct 2007301 gtcacattcg actgaacata attcagcatt tgggctgctt tcgttatgct tccttcgcga 2007361 gcaacagcct gaaaaatctt taaatctccg ctttccacgc gctctcacct gcttgctatg 2007421 atgaaaagtg atattggcta tcatatttgt tcattttact cgaagaaaac cgctatgtaa 2007481 aatatgtaaa gatatgaaaa tacaattaat gaggaggcag acagcatgaa agctgtaatt 2007541 cacaacggaa aagccggtct tctggggtta tcagttcagg acgttccatc aacaaagcct 2007601 ggatacggag aggtaaaggt taaattaaaa tctgcaggcc tgaatcatcg tgacttgttt 2007661 cttatgaaaa acaaatctga acaagatcct cacatgatac tgggttctga cggcgcgggt 2007721 atcatcgaag agattggtga aggcgtgaaa aatgttactg ttcagacaga agtagtcatt 2007781 ttcccgacat tgaactggga tttgacagaa aatgttccac ctgtacctga gattctggga 2007841 ggtccttcgg acggaacact tgctgaatat gtgatcattc cttcacaaaa tgcaatcaaa 2007901 aaacctgctt atttatcttg ggaagaagcg ggcgttttac ctttatccgc tttaactgca 2007961 tatcgggctc tgtttacaaa ggggcaatta aaaaaaggcg agcatctatt gatacccggc 2008021 atcggcagcg gtgtagcaac ctacgcttta tttatggcta aggcgattgg ggcaacagta 2008081 agcgtgacct cccgcagtga ggagaaaaga aaaaaggcgc tgaaattagg tgctgattac 2008141 gcatttgaca gctacagcaa ttgggatgag cagttgcagg gaaaaaagat agatgttgtt 2008201 cttgacagca taggacctgc cctcttttcg gaatacttcc gccatgtaaa accaaatggc 2008261 cgtattgtca gctttggggc aagctcaggg gataatctca gttttccggt gcgttcttta 2008321 ttctttcctc aggtcaatgt tttgggaacc tcgatgggaa gcggtgagga atttcaagct 2008381 atgctcgctt tcattgacaa acataagctg cggcctgtaa ttgaccggat atatccttta 2008441 gaaaaagcat gtgaagcata taaaagaatg caggaaggca gacagtttgg aaacatcggg 2008501 atcgtaatgg aataaaaaaa gaaaccggct ggcagccaga ccggtttctc ttatatgata 2008561 atccccttta tttacggaag aactgaactc cccatcaaat atcgatccac ttcacgcgcc 2008621 acttcacggc cttcattaat cgcccatacg attaagcttt gccctcttct tgcatcccct 2008681 gcggcgaata caccatcgat atttgtttga taatccccat atgctgcact gattttgtta 2008741 tttactgaat taacaccgaa ctgtttcaac agcggctgtt ctgtgccttc aaagccgata 2008801 gcgataaaga caagctgagc aggccatact ttttccgttc caggcagctc gcggaactcg 2008861 tattttccat gctcattttt cactttttcc atttggatgg tatgaagctc tttcagcttt 2008921 ccgtttttat ccgcgaccat ttttgtcgtt tgaatggagt attctctcgg atctcttccg 2008981 aattttgctt ctgcttcctc gtatgcatat tcaagcgtaa agacgtgtgg ctgttcaggc 2009041 cacatattgt cattcgtgcg ggctggcgga agtttcgggt gtttgccgaa ttggtgcacg 2009101 cttttggctt tttgacgcag agcggtagcc acacagtcag ctcctgtatc tccgcctccg 2009161 attacgatga catctttccc tttggcatca atgaattgct tgtctttaaa attagaatct 2009221 aaatagcttt ttgttgcaag tgtgaggtag tccattgcgt aatggactcc ttttgagtcg 2009281 cgtccttcga ttaagaggtc ccgctgtttt tgagcgcctg tgcataagat cacagcatca 2009341 aattgctcct ttagctcatc agctgtaatg tcaacaccga tttctgtgtt cgtgacaaaa 2009401 tcaattccct cttgcgtcag caatttaatt cggcgttcta caatgccctt ctcaagcttc 2009461 atgtttggaa tgccgtatgt taaaaggccg cccgctctgt ctgctcgttc aaaaacagtg 2009521 acggaatgtc ccgcttgatt cagctggtca gcactcgcca gtccggctgg gcctgacccg 2009581 acgatggcca cttttttgcc tgttcgtttt tttggaattc taggttgaat ccagccgttc 2009641 tcaaatcctt tatcgataat ggtccgctcg atgtttttaa ttgatacggc cggatctgaa 2009701 atcgctaaag tgcatgatcc ttcacaagga gcggggcata cccgccctgt gaattcagga 2009761 aagttgtttg ttttcaacag acgttccaat gcttccttcc atctgccccg gtagacaaga 2009821 tcattccatt caggaattaa gttgtaaatc ggacagccgg atgtaaatcc gttaatgtcc 2009881 gcaccgatct ggcaaaacgg tgtaccgcaa tccatacacc gcgccccttg ccgtttcgat 2009941 gcttcttctg aaaaaggagc agaatattct ttccaatcct ttaagcgagt gagagggtcc 2010001 cgctccgcag gtttttctcg tttgatctcc ataaatccag ttggtttccc catgttcctc 2010061 tccccttcct tactgtacta ccgcttgttt ttgtcccgat gctgctgtat tctgctttgg 2010121 cttcgtgttg gcctcaaaag cgaacatgat ggcttcttca tctgataaac ctgcagcttt 2010181 ttgctcttcg atgcttgcga gcatttgttt atagtttttc ggaatgactt tgacgaattt 2010241 tttcacactg tcttcccatt gatctagcag atcttctgct ttttggctgt ttgtatacgc 2010301 agtatgtctt tcaagcattg ctttgatttg ctggatttct ttctcatcct ctaatgattc 2010361 aaataaaatc atctcaaggt tgcatttgcg tttaaacgct ttgacatctt cggtcagtac 2010421 ataagcgatt ccgccggaca tacctgccgc aaagtttttg cctacatcac cgagaacgac 2010481 aacgctgccg ccagtcatgt attcacagcc gtggtcgccg atgccttcta caactacgtt 2010541 cacaccgctg tttcgaacgg caaagcgttc accagcacgc ccgttaatat atgcttctcc 2010601 gcttgtcgca ccgtaaaaag ccacgttgcc gataatgaca ttgtcatccg aagcagagtt 2010661 gaatccttct gatgacttga cgatgatttt tccgccagaa agcccttttc cgacgtaatc 2010721 atttgagtct ccgtccaaat aaagcgtcat ccctttagga acgaaagctc caaagctttg 2010781 gccggctgat ccggtaaagt gcagcttgat tgtatcttca ggaagacctt cttctccgta 2010841 acgctttgag atttcactgc cggttatcgt tccggctaca cgatttgtat tattgatttc 2010901 aatcgaaata tcagcttctt ttccagattc gatggcttct tgtacggccg ggagaattgt 2010961 tgtaatatca agtgattgat caattttatg attttgcggc gattggaacg tccgcacccc 2011021 ttcaggctga taaagaaggg tagacaaatc aagctggctt gctttccagt gctcctttgc 2011081 ccgttcactt gcatgaagta catcagtgcg gccgatcatt tcatcaaatg tcttgaagcc 2011141 taacgcagcc atgtactcac gaacttcttc ggcaatgaac agcatatagt tcacaatatg 2011201 gtcaggatct cccatgaact ttttgcgaag ctctggattt tgtgtcgcta caccgacagg 2011261 gcatgtatcc aaatggcagg cacgcatcat gacacagccg agtacaacta acggagccgt 2011321 tgcgaaacca aattcttcgg cgccgagcaa ggcagccatc acaacgtcgc ggcccgtcat 2011381 gagctttcca tctgtttcta atacaacacg gtcacgaagt ccgttcagca ttagtgtttg 2011441 atgtgcttct gcaaggccaa gctcccacgg aagccctgta tgtttaatac tggttttcgg 2011501 agaagcgcct gtacctccgt catagccgct gatcacaatg acatctgcag tcgctttggc 2011561 aacacctgca gcgattgttc ctacacctgc ttttgacacc agctttacgc tgattcttgc 2011621 gtcacggttg gcatttttca aatcgtggat cagctgggct aaatcctcaa tcgaataaat 2011681 gtcatggtgt ggcggaggtg agattaatcc gacacctggc gttgacccac ggacatcggc 2011741 aacccatgga tataccttgt tgccaggaag ctgcccgcct tcacccggct tagcaccttg 2011801 agccatttta atctgcagct catcagcatt gacgaggtaa tggcttttga caccaaaccg 2011861 tccggatgca atttgtttga tcgcacttct tctatcatcg ccgttctcat ctggaacaaa 2011921 gcgtttggga tcttctccgc cttcaccgct gttgcttttt cctccaagac ggttcattgc 2011981 gattgctaaa gcttcgtgcg cttccttact caaggacccg aatgacatcg cacccgtttt 2012041 aaaacgtttg acaatcgatt cagcggattc aacctcctcc aacttcaaag gcttgcggtt 2012101 tccgtcaaat gcgaacaagt tccgcaaaaa tccgatgcgt tcttcatcag ccgcttttgt 2012161 atactgttta aacagattgt aatcatttct gcggcacgcc cattgcaaag tatgaatcgt 2012221 tttcggatta aacgcatgat gctctccgcc atttctccat tggaagtcac ttcccggttc 2012281 aagcgttttg ctgtaatcat cctgatacgc ttcccggtgg cggcgctgtg cctcttctgc 2012341 aattgtttgt aaatcgatgc cgcctagctg tgatgcagta cctgagaaat agcggtcgat 2012401 cacatcgcgg ctgattccta ccgcctcaaa gatttgtgcg cctctgtagc tttgcacagt 2012461 tgaaattccc atcttggaca tcacttttac gacgccctca gtaatgcttt ttccatattt 2012521 gctaaccgct tcttcatagc tgatatccaa acggccttca tcaatttcct gcttgtaggt 2012581 cgcataagcg agataagggt taatcgcatc tgcgccataa ccgattaacg ctgcaaagtg 2012641 atgcacttca cgtgcttctc ccgattccac aataatgctg accttcgtac gcagcccttt 2012701 gcggattaag tgctggtgca gtgcgcttac tgccagaagc ggcggaattg gtgtcagtcg 2012761 ttcgttcatc tttttgtctg ataaaattaa caaacttacg ccttggctga tggctttctc 2012821 tgcctgtgtg aacatgtcct ttaaaccgcg ttcaagatcc tctgaaaaca gcacatcaat 2012881 tttttggctt tttaaatcag gatgaacaat cgttttcaat gcgtaaaact gttcattgga 2012941 taaaacaggt gtatacagtt taatccggcg aacatttcgt tcacttggat gaagaagatc 2013001 gccttccgca ccgagccaag tcatcgttga agtgacaagc tgctcacgaa tcgcgtcgat 2013061 tggcgggttc gttacttgtg caaacagctg tttaaagtag ttaaacagcg attgcgctcg 2013121 gtcagaaagt acagcaagcg gagcgtcatt ccccattgaa ccaaggggat ctttgccttc 2013181 tttaataaca ggaattagat acttttggat atcctcatat gtgtatccga atgccttctg 2013241 gcgagtaaga agatcactaa attgttcttc ttctcttgac tccggatcag gatttacttg 2013301 tacaagctct tcttcaagcc atttttggta cggatactca gttgcaattt gtgttttgac 2013361 ttcctcatcg gagataatac ggccttcttc caggtcgatt aaaagcattt tcccaggctc 2013421 aaggcggttt ttatataaaa cgttctcctg ttcaacttca ataacgccta cttcagatga 2013481 gaaaataata taatcatctt ttgtgacata ataacgggcc ggacggagac cgttccggtc 2013541 aaggatcgcc ccgatttgtt taccgtcagt aaatgaaata gctgtcggtc cgtcccaagg 2013601 ctccatcagg gagctatggt actcgtagaa cgcccttttt tccttggaca tatgcgtatt 2013661 ttccgtccaa ggctctggaa tgagcatcat tgccgtatgt gccggtttgc gtccagccat 2013721 cacaaaaaac tcaaatgcgt tatccaaaat ggaagagtca ctgccatcag cattgagaat 2013781 cggcaaaatc ttgtttaagt cctcaccgaa gctttcagaa acaaattgct gctcacgtgc 2013841 tctcatccag ttgatatttc cgcgaagggt gttaatttca ccgttgtgaa ccaaatagcg 2013901 gttaggatgc gctctttccc atgtagggaa tgtattggta ctgaagcgtg aatgaacaag 2013961 cgcaaaagca gaaacgaatg cttcgtcttg cagatcagaa taaaatgcat caacctgttc 2014021 aggtgttaaa aggcctttgt aaacaatggt ctggcttgaa agactggcaa aataaaaatc 2014081 aagaccttcc gttactcccc aattttcagc ctgtttacga atgacataca attttcgttc 2014141 aaaagataaa ttgtccttta gatcagaact tgcgccgata aatacctgac ggacaaacgg 2014201 acagcttttt tgcgccactg ttccgatttt tccgacattt acaggtacag ttctccatcc 2014261 aagaacgact tggccttctt gttcaattag tgcattgatt tgcttttcaa ttttttttct 2014321 ttcatcttcc ttctgtgaga aaaagaccat tcctaccccg taacgttctt tttctggcag 2014381 attgatgttt ttgcactctt ttctaaagaa agcatcaggg atttgaacca gtaagccggc 2014441 tccgtctcct gtatccggat cactgccttg ccctcctcta tggtctagct ggcaaagcat 2014501 cttaagtcct tgtttgacaa tgtcgtgagt ctgcttgccc tttaagtgtg catataggcc 2014561 gattccgcat gcatcatgtt caaattcagg acggtagaga ccttgagctt ttggcatttg 2014621 attgtacgtc ataattcctc tcccccgatc aatttccgat aataccggtc ataaaatcta 2014681 acaactctat aatcattgta ggttttcaaa acgatataaa caatatataa tttagatcaa 2014741 aagaatctca aaatgagata gatggatgtg agacaaacat ggagctgcgc caactgcgtt 2014801 attttatgga ggtggctgaa agagaacacg tttcagaagc cgctgatcat ttgcatgtgg 2014861 cccaatcagc aatcagcaga caaattgcca atcttgaaga agaattaaat gtgaccttat 2014921 ttgagcgtga agggagaaat atcaaactca cgccaatcgg aaaagaattt ttaattcatg 2014981 tgaaaacggc gatgaaagcc attgattatg cgaaagagca aattgatgag tatcttgacc 2015041 cgcatcgcgg aacggtaaag atcggctttc ctacaagcct cgccagccag cttttgccga 2015101 ctgtcatttc agcgtttaaa gaagaatatc cgcacgtcga atttttgctg cgccaaggct 2015161 cctataagtt tctgattgaa gctgtcagaa accgcgatat tgatctggcc ttattagggc 2015221 cggtgccgac gaatttctct gacataacgg gaaaaatatt atttactgaa aaaatttacg 2015281 cgcttgttcc attaaatcat ccgcttgcta aacaaaaaac ggttcattta atcgatttgc 2015341 gcaacgacca atttgtattg ttcccggaag gatttgtact tagagagatg gcaatcgata 2015401 cttgcaaaca agcaggcttt gctcctctcg tttccacgga gggtgaggat ttggatgcga 2015461 tcaaagggtt agtgtccgca ggaatgggcg ttacccttct gcctgaaagt acttttgctg 2015521 aaacaacacc tcgttttact gtgaaaattc caattgagtt ccctcaagta aaacggactg 2015581 tcggaatcat taaaccgaaa aatagagagc ttgcgccttc cgcgaatgat ttttatgagt 2015641 ttgtcattca atttttctct aagctggagc agtatcaata aaaaaaatga acccgagctt 2015701 ctatatagaa gcttcgggtt tttttctgca aattaattta caggtaaaga aaaatccaca 2015761 tggcaaacaa atgcttcttg atcaattaga gctctatttg tcagttcctt tttcttttcc 2015821 ggttcttgaa gctgtacaga agagtaattg acgattccaa ggccgatttc cgtccctttt 2015881 gaatccatca gccgaacaac tgaaccgctt ttgaatttcc ctttaatctt ctgtacaccg 2015941 tctaggtata aactcgattg tccgtttgtt atttttcgtg aacaatcatc tgataaaatc 2016001 atttcacctt ccggaccgga attaaaagcg atccattgct ccttttgatt caacggaagc 2016061 gttccttctg cttcaaaata ggtgccttcc gcctgttcat gaacggcgtg gtataaaata 2016121 tcgccagcat ctgcctgacc taggaaacct ttaatgccag acgccattac gattttaaac 2016181 gcatcaagct tagagcgcat gccgccggtg ccaacgatgc ttccagtgtc acctgcgcat 2016241 gcttcgatgt caggtgttat ttcactcacc cgctgtatct ttttcgcttc tggatttgtg 2016301 cgcggattgc cgtcatataa tccgtctata tctgataaaa tcacaagcat atctgcatca 2016361 atcaatcctg cgacttttgc tgcgagcgta tcattgtcgc caaacttgag ccgattgacg 2016421 gtaactgtgt cattttcgtt tatgatcggg atgatgccgc gctcgagcag tacattcatt 2016481 gtattcctga cattgttgta tcgatattca tcagaaaaat cgcttctcgt aattaaaatt 2016541 tgggatgcga catagccgtg tgccaaaaac agctttgaat aagcctccat tagcaatccc 2016601 tggccgattg aagctgatgc ttgtttttct ggaagcttct cgggcctttg gataaatccg 2016661 agcttccgat atcccgccgc cactgcgcct gaggaaacca aaatcacttc ataaccggcg 2016721 tctttgagtt tgacgacctg gtcgaccaac gcttctaatt ttcgaatgct gatttctcca 2016781 tgaaggcttg ttaatgaact gcttccaatc ttcacaacga ctcttttcat gcttgtatca 2016841 ggcgtcactt tatcactcct gatagcggcg ctgcagtttt ttcgatatct tcgctgattt 2016901 cctttgaacg cttagccgca tgctttattg cttgagaaat cgcttctccg ccgccgctct 2016961 ttttcaaggc ttgcagcccc gctgctgtcg ttccgttcgg tgacgtgata ttatctctta 2017021 agatctcagg atgttctcct gtttccatga gcatttttgc ggcacctaaa agtgtctgtg 2017081 cgccgatgct tcgagataac tgtttatcga ggcccgcttc ctcgcctgtc ttttcaatga 2017141 attccattaa ataataaaaa tacgcgggtc cgctgcctgc aattccggtg aatatatcca 2017201 tttgattttc ttggattgta tagacttcgc ccatgcatcc gagcaatgct tcggccagct 2017261 tcttcaggtc ttccgacaca tatttgccaa gggcaatagc tgttgcagaa gcgccaatca 2017321 tactggaagt gttgggcatc actctgacaa ccggctgttc attaagcaat gattgttcaa 2017381 taaaagaggt agttatgccg gcaaggaccg acaatattaa ttgatggggt tgaatacgtg 2017441 attttagtga tgacagagcg ttttcggcgt cttttggctt cattgccaaa atgagcacat 2017501 ccatgtcttc aatacatagt tggttcggca aggcgccttt aatgccatat tgaagttcaa 2017561 gttcagttaa tcgctctgta ttgctgcggt ttgtaacgca gatgttttgt ttcgggattt 2017621 tgttggctcg aacgatacct gatatcattc cttccgccat agatcctgct cctataaagg 2017681 ctactttctt ttgatcaaag atcggtaaca tctcctttgt tcgctttttt gttcgcattt 2017741 tcacacgttt aaaatgttac cacgtgagga aatgatgtca agtttgaagg ccattattga 2017801 tttgtattgt ttcttttcga caaatatgta taatgaaaag cagaaaacac ccggttcaca 2017861 ctgctgcgcc gggtgtttgt ttctattaaa aattatctga gagagctttt tcaatcagtt 2017921 ttttacagcg atccagctct accttcagct gttttttata tagcttggca gcttcgtaat 2017981 ctttaaattg atagaggacg acttcctgga gcttagcccc ttcttttttt actttaattt 2018041 gttttagtat cccgtcatca agaagctcat gcaaagaccg gtatacttct gtatgatttg 2018101 gtttaaaacc aatctcttta aattcagacc gaagtacttc aagcagcttt aacccataga 2018161 gtctctcttg ctctgtcatc gttatcatat aaagcttcaa aaatgcgcgc tgtttcacta 2018221 aaaagcctgt tgaactcctt ttttcttctt tcatcatatg cactccttct tctgtcactg 2018281 acaacactat gtactaaata ttcaattttc ttttattgtt ttccttcttt atattaaaga 2018341 ctgatagtcc agttatttca tgtttactga ttataggtgt agcggaaaaa ataaatttcg 2018401 actgaacatt tggtacatag ttttcttagt tctattatag cctgcattta ctgctatctt 2018461 caatttaaac gattgccagg gtttacatat ctcattttac cggtacggat ttcattcaaa 2018521 taaaaaaacc tgtcgaaaga caggttttca tttttaagga tttgttgacc ataatcccgc 2018581 tgttttgatg aaaatacgag gatctaattt cagttgtgcc accatgtact cagcaagatc 2018641 ctcaggctgc ataacttttt caggattacc gtctgttaag ttcaattcga tagacatatc 2018701 actagcgaca gtgctcggcg ttaacgcgct gactctgata ttatgttttc tcacttcttg 2018761 cataagagac tctgttaacc cgagaacggc aaatttagaa gcgctgtaag cacttgttac 2018821 agcagctcct ctttggcccg ctgtagatga aatattaatg atgtctccgg ctttgcgttc 2018881 gatcatttcc ggaagcaccg cgcgagtgac atggtacaca cccattaggt tgacttgaat 2018941 aatattttcc cactcatcag ctgacagatc taagaaaccg ccaaatttgc tgatgccggc 2019001 attattaatg aggatatcga tatcaccgag ctgttccttc acttgagcta cagcttggtt 2019061 aacctgatcg gcatctttta catctgcagc agcaaatgca gcttttacac caagcgcttt 2019121 gacttcttca gccacttttt ctacattagc ggaagtccgg ccaattaacc cgatattcac 2019181 gccttctttg gcaagcgcca gagcagtagc gcggccaatt cctctgcctc cgcctgtgat 2019241 tagtgcagtt ttatgttgta aactttgcaa ttgaagcacc ctttctttgt ttacatatgt 2019301 acgatatcac attataagta caatacatcc aatacgcaaa tcaaacgaac tgtgtaaata 2019361 tcatttcttc tgattaaaaa aacggataca gggtaatgac ataagaaaag gagtgaacat 2019421 atgattatag tttatatcag tcttgcagta ttagcagttt ctattatctt cttaggagtt 2019481 accgtgatcc aaaacaagaa aaaaatagac cccgcactaa aggagctttc ctctgttacg 2019541 caggctatgc aaaaacaaat cgaaggatta aaaacagaaa cagagctgct gacgcaaaaa 2019601 caaaagaaga ttcagcagga tgtccaaata aaaaaataca cgcttcagca gaccgcagct 2019661 gaagtgaaag aagttcccca agcagtcaaa gaggtgtggc aggcaggaca ttttaatagc 2019721 agataaggat gaatgagatc ccgttgttac gatcagaatg gacaaatggg atctcatttt 2019781 tcgaggaggc ttacacatga ttataaaccg cagctgctta aaagagttcg cagaaaaagt 2019841 acattttctt ccctcttcac ttacaaagtc cgatttactt actgatccat ttcgtctcca 2019901 tcaagaaaac gaacttggca tctactattc acctcataat gaatttatca atcgggatgc 2019961 ctcgcttgtg attgccggga tcacgcctgg tttttcccag atgaagacag cgtacgaaac 2020021 agccgccgaa agcctgctgc aaggcgggac tcttgagcaa atggcagtag acacaaaaat 2020081 agcagcgggt ttctccggat cgatgagaca taaccttatt accatgctgg atttatgcgg 2020141 gctgccgcaa gcttttggca ttcaaagcgc cgcaaagctt tttggagaat tacggcatat 2020201 gctccataca acttccgtta ttaaatatcc tgtctttatc cagcaaaaaa actataccgg 2020261 atacaaaccg gctatcactc attctcctat cctaagcact tatgcttttg ggcacttccc 2020321 tgcagagctt aaccatgtga cgggaccagc tcttctcatt ccgttaggaa aagcggccga 2020381 aacagtgtgt gaaacattga tcagacagca cagcctccag aatttgattt gccttaacgg 2020441 ctttccccat ccatcaggcg cgaacggcca tcgtttgaaa caattcagca aaaacaaaga 2020501 gcaactagaa agacaaattc gttcctttgc tgcattggtt gatttcgcta tagaaaagag 2020561 gaaataaaag ggatatgata aacaaaaaca caaacgtggg gagtggttga atgtttccta 2020621 tattagaaac ggatcggctt atacttaggc aaatcacaga tcaggatgcg gaagccattt 2020681 ttgcttgttt ctcaaacgat gaggtgacac gctattatgg gcttgaaaac atggaatcta 2020741 tagaacaggc catttcaatg attcaaacgt ttgctgccct ctatcaagaa aaacgcggta 2020801 tacggtgggg aattgaaaga cgggacacta aagaactgat cggaacaatt ggctttcacg 2020861 ctctggccca aaagcatagg cgcgcggaaa tcggttatga aatcatcccg gagcattggc 2020921 gaaacggatt tgcatcagaa gtcatttcaa aggtcgtatc ttacggattt tctgcccttg 2020981 gactgtcgcg tattggcgca gttgtattta ccgataatga agcatcaaat cgtctgcttc 2021041 taaaaatggg gtttcaaaaa gaaggcgttt taagacagta catgtatcaa aatgggactc 2021101 catatgatac aaatgtgtac tctattgtga aaccaagaga atgacggtat tctcttggtc 2021161 tgtgccacat cccttttcct ttaaaaagat aaaaagcgcc cctcaaacag ggcgctttct 2021221 aattaagatg catattgagg agatgtttcc tccttaactg ctttttcctc aggtatatga 2021281 atacattttg tcaagaccgc acttgcaagg taaagggccg caaagatcca gacgacacct 2021341 tgcgcgccga cgagaccgat gaacagccaa gcgagtgcag ggccgacaaa cgctgataaa 2021401 cctgcagcta aattcaatac agacatggct gcccctttat cttttcctgc caccgtcggc 2021461 acaattgcac caatcggcac atagcctgcc agcaaaccgc cccaaataaa gccgatcacg 2021521 ctgacaaccg ctaaacttcc gccggagaaa acaggtgcgt agtataataa gacggtgaaa 2021581 atgccgcagc cgactccgcc gaaccaaata acagtatttt tccagccgaa tttatcgccg 2021641 acaataccga agataaggtt aaacacaatg ttccccagga aaatcgttcc ccaaatttgc 2021701 agccacacat tggttgaaat tccatgctgg gccatgtgca tcggcaaaaa gactggaaaa 2021761 ccatatgtac caatgctgtt gatgattctg atgattccgc ctgtaagcac gcgcggattt 2021821 gtaaatagaa tcgtaacccc ttttaaaagc tcctcggctg tttctgatct ttttcttttc 2021881 ttcttttcaa aacggtcttt attgataaac aatgcaaaga atgcaccgag acatacccag 2021941 aaaatagagc tccaaagcgt attcaaataa ccgaacgctt tgatcgcgta gcttgagtac 2022001 caagcgccga acacaaacat gccgaggcaa tatgcaatcc aaaaccagcc gacagcagtg 2022061 ctcagtttgc tttgcggtgt tctgtaaatg acccatgtca agaaagaata agcaaaaagc 2022121 gggtaaccta acccttttac gaagtaagtc acatacatca ctggcaggtt cagctgttca 2022181 aatccaaata cgataaaagc agctgtaccg atcacataaa acaacagccc cataaacatc 2022241 gttcgttttg cgccaaatgc ttcgagacat acacccgaaa accaggaagc tatggcaagc 2022301 gcaattccgt atatactaaa aatggaagcg gactgctgaa cggtgagccc gttttcgatc 2022361 aaaaaaggac tgagccagcc ttgttcaagg ccatctccca tcataaacaa aacaacccct 2022421 aaaaatcccc aggcaagccg cttcggtatt cctattttat ccaacatatc tgtctcctcc 2022481 ttagatgcta ttattcatta ccgtattacc ttattaaagt tgaaaattaa atgattcctc 2022541 aaaacagcag aaattccgtc ttaaattaat actttgcttt ctgatcctga aaaaaagcgc 2022601 tgtgtttgct tccattcctc atataaagcc aattctatct gacagtcctt cggttcgatc 2022661 acccggacat ttgctgacat ctcctccgtt aattgaaagg tttcattgca aatgactgca 2022721 gcaccgacga cagatgcctg atgatatccc tcttggacat agaccttttt ttgaagaaga 2022781 tccgcgatat attgagtgag cgctttgctt tggaatcccc ctccgcacac ccaaacataa 2022841 tcacgttcaa acggagtaac ctctgttaaa atgtcaaagt tccatttgat tgaaaatgcg 2022901 atctcttcta gcgctgcacg tacaaaatgt gccctcttta aatgtgctga cagcggggca 2022961 tcaaaaagaa aaccgcctct cgttaacgca ttcttttcag ccgataaata agagccgaga 2023021 gccgctacac atgcatggtc ttcttttgca agtgcagaaa tctcctcctc cattacttcg 2023081 tacgtttcat tcggataaaa aatctgtttt aatttttgat aattcaagcc ggtaattccc 2023141 ggattcgttt ccacaagcca atgcccttga tccgtatgac agttcaacca ggctttatgt 2023201 tttgtgtcgc catgatcctc agtaattttg gttattggcg ttgttgtccc tgatacaatg 2023261 acaatgtcct caagtccagc tccggtgctt ttgacagcca gctgtgtatc cccgccccct 2023321 gctataacct tagcatttat tgaaaggcct aattcggatg catattcatt tgctatcgtt 2023381 ccaattgctg ttcccgctct tacaagaggc ggaaggatag atggagaaaa gccgaaaatg 2023441 tcgcacatct cttctgacca agtgttttgc ttcacatcaa atagcagggt ttctgttgcc 2023501 tgtgatggtt catatgttaa tattccgctc agttggtacg tcacccaatc actgatgctt 2023561 gtaaagcttg cagtcttttc ccataaagag ggctggcgct gttttaatcc ataaagcttg 2023621 agcgcagaaa aaagtgcagt tggcaggcgg cctgtgctgc tgtatatctc ttcccaatcg 2023681 ggaatgcccg cctcccactc tcggccgcga ttatcgatgt tcggcagccc gagaaaagga 2023741 ttgccgtttt gatcaatcaa aacaatcccc tgtctttggc tcgtcgatgt caaaccaatg 2023801 atgtcaatat cacacgaacg ggatagcgca cgttttgcca aattcatcac ctgcttccac 2023861 agcacctgag gagaaaaata acggctgtcc gggtaaagcg tctctgtgga atactcgatg 2023921 tcctcccgtt caactgttag aacactgcca gttacactca cgaccgctac cctcgcattg 2023981 cctgtgccaa tatcaaaaac gagatagcct ttttgttttt tcattctgtt agcctccttt 2024041 cttatccccc tgttttcagt gcgtccttgt tatacattgt ctgaatatta agagtttttt 2024101 cacccttcca ctttttgagg gctttattca gtatcgtcac gtgatgatcc tccacttcaa 2024161 atgttgctcc agcgagatgc ggtgttgcca gaacattagg caatgaaatc aattcataat 2024221 ctgattcctc tggaggttca tgataaaaaa cgtctagtat cgcaccgctg attttatgtt 2024281 cttttaatac aaataaaaga tcttcacggt ttacaacaac tgctcttgaa gtattaacga 2024341 aaatcgcact ctctttcatc agatcaaaat attgccgatc tatcagtccg agtgtttcct 2024401 cagtgcgagg cagatggaca gaaacgatat cgctgtctga aaacaccgtt ttaagagatg 2024461 ctttttcata caacggatga tcgtcttgaa tgtatggatc gtaatatttt atcttacagt 2024521 caaacgcagt cagcagtttt gcaatccttt gcccgactgc gccgaaccca atcatgccaa 2024581 ccgtttttcc tgttagctca tttcctttaa atttgacata agcctgcagg taatcactgt 2024641 cccactctcc atccttcagc cactgattcg aggcgctggt atggcgcaga aaggaaatca 2024701 catttccaat aaacatttcg gcaacggctt gtgcattccg ccctggtgta taaaaaacag 2024761 gtatgcccct ttttgaggca gctgccacat ccacatttga gggcattccc ctgcaaacac 2024821 cgacaaatga aagttcggga acagaagcaa atacgctgtc tgttacctga tcaagttcag 2024881 taatcaagcc tgtcgcattt gttgctttta gcagctgaat gagttcatcc tcccgatatg 2024941 ccctaccttg ttccttccaa gattgataag caactgagcc aaacaagttt tcaagctctt 2025001 ttcgtccttc ttcgttgtac ggtgctgtaa ccaaaaccgt catgctgcaa aacatccttt 2025061 tcatcgtatt tttcataaaa aaaatctctt tccgaagatg gaaagagatt catatatagg 2025121 cgcgctctgt tacaggcaga cgccggtata aaccttgctt tcctatcttt caagctagcg 2025181 cttgctggaa ttggcacaat aatgttgccg aggtttcata gggccagtcc ctccacctct 2025241 ctggatagaa aatattgagt atgtaatttt cagaatgaag aatacgttta tcataaagaa 2025301 gactcagatt gatgtcaatc tctttttttc agaattgacg ttatcatcgg aaatgttata 2025361 attcttacaa aatatctaac tagagagagg aactgggcca tgagatcttt tgccacacaa 2025421 caaaacggca ttttcaaatc cgtttgctcg ctggactgcc cggatcagtg cggattgtta 2025481 atacataaaa aagacgggaa aatcgtaaaa gtgcaaggag accctgatca tcctgtcaca 2025541 gctggaaaca tatgcaacaa agtccggaat atgacggagc gcatctatga tgaaaagcgg 2025601 ctgactacac cgctcaaacg aacaggtgcg aaaggccaag cgatatttga accgatttcc 2025661 tggaaagagg caatcgatac gatcacctcc cgctggaaac agctgattga tgaagaggga 2025721 gctgaaagca tacttcctta cagcttttac ggaaatatgg ggaaattgac agctgaagga 2025781 atggaccgcc gcttttttta ccgcatgggg tcaagccagc ttgaacggac gatttgcagc 2025841 aaagcgggat ctgaaggcta taaatataca atgggcataa gcgcgggaat cgatcctgag 2025901 gaaaccgttc atacaaaact atttattttt tggggaatca acgcggtcag cacaaatatg 2025961 caccaaatta cgatcgccca aaaagcgcga aaaaaaggtg ccaaaattgt cgtgatcgat 2026021 gtgcataaaa atcaaacagg acgtcttgca gattggttta tcccaataaa accgggaacc 2026081 gacagtgcac ttgctcttgg catcatgcac attttattta aagaaaacct tcatgatgaa 2026141 gcatttctgt ccgagtacac ggttggctat gaagagctcc gtgaacacgt gaaacaatat 2026201 gatcctgaaa aggtatcgac gatcaccggt gtcagtaccg aagatattta ccgactggca 2026261 aaaatgtacg gggaaacctc cccttctttt atcagaatcg gaaacggacc ccagcatcac 2026321 gataacgggg ggatgattgt aaggacgatt gcctgtcttc cggcgatcac cggccaatgg 2026381 ctgcacacag ggggcggcgc aattaagcat aacagcggaa ttttagaata taacacaaat 2026441 gccttgcagc ggcccgactt attgaaaggg cgcaccccga ggtcgtttaa tatgaatcag 2026501 cttggcaggg tgcttttgga aacagacccg ccgattcgct ctctatttat ttacggaacg 2026561 aaccctgccg tcgtcgcgcc cgaagcaaac aaagtcagac agggcttgct gcgggaagac 2026621 ttgtttactg tggttcatga tttgttttta acggaaacgg ctgcatatgc ggacattgta 2026681 ctgcctgcaa catccgcttt tgaaaatact gatttttaca cctcctactg gcaccattac 2026741 attcagcttc agcagccggt gattgagaga tatggggaaa gcaagtctaa cactgaggtt 2026801 ttccgattac tggctgaagc catgggattc acagaccagg agcttaaaga ttcagatgaa 2026861 gtattaatcc gccaggcgct tgaccatcca gataatccgc atttggcaga gattgattac 2026921 gattcactta ctaagcattc atttatgaaa gcgaaacgtg aaaagccgct gtttccgggc 2026981 gaacttccaa cgccaagcgg aaaaatagaa ttatattcag aaaaaatgaa acaagacggc 2027041 ttccctgctt taccgacata tacacctctt gtaaccgata atgaacatcc gtttatgtat 2027101 gttccggggc caaaccataa tttcttaaac tcaacatttt ccaataatga aaaacacatc 2027161 aagcttgaaa agacgccaaa gctctttatc aacacaaaag atgctgaaaa acacggaatc 2027221 gttgatgggg cacctgtacg aatttggaac agccggggag aatgcgagct gaccgctgca 2027281 gttggagaac aagtgctgcc aggtgtcgtt gtcagccaag gattatgggc ggatgaacaa 2027341 ggaaaaaaac agcttgtaaa cgcgctaacc ccagatcgct tgtccgatat gggcggcggc 2027401 gccacctttt tttcaggccg tgtacagatt gaaaaggttt gaaaaataat gaaacccgga 2027461 gtatgccaag cccgtataac ataacatcga cataatggag gcatacacat ggacgttttt 2027521 ttaggaattg gtattgcttt ggctggatat tttatcggtg aaggcttaaa gcagaggaac 2027581 caaaccaaag gtaatgaaca aaatgatatc ttcctaataa aagaacggga tatttacttt 2027641 tacattggac tttttttagg aataacaacg actgaagcaa aacagttagc tggagacatg 2027701 gcagacctgc cttacatcga aataaacgga aaaaaatatg tccagaaaca tatgttaaaa 2027761 gattggacat tcacattagt tgaaaaacat cagggtgaat aaaacaaatc tgaggagagc 2027821 gagattcatt gtcacgctct cctctgttta gctgtatgga tcctgccacc aaaactttgt 2027881 gctataagcg ctgataaaac gataaaccac catctatgtt ctttcctcaa acaactcaag 2027941 atgcccgttc cacaacaata gtttttatat tcctttgatg acgtgatgtt cttgatgaac 2028001 gtatgtatcg taaaacactt agaaaaccta ttcggtttga atgtgtgctc tcattatgcc 2028061 cccatactgc gcctttatcc gcggaggatt tttttaaaaa aatatgaaac ctaaagcttt 2028121 tagatcctga atttttattg aacctccata tttctccgat tggtaaaaat tagcctatac 2028181 accggaagct gtacgtttat aaaggatcag agaatcccat aaccagtaaa tcactgcagc 2028241 cgcaatactt aacatataat aaaagtacga ttgcaatgtc catgctattg acgcaggttc 2028301 attgataaca aaaaacagga aagctgcgat aaaagcaacc acactgtaaa tcaataggta 2028361 catgacattg aaagttctcg cttttttctg caacttcatt tggagcggaa cagcaaaaag 2028421 gccatacacc acaaaaccgt ataataaagc aattgctgcc gtaaacaatg caattatcat 2028481 atcgccatac ataacgaaag aataaaaccc taataacaaa ccaaatgtaa ggctggatag 2028541 ccctaatgtc attaaataat atgatgcgat ttttttcatt ttttcacccc ccttgtttga 2028601 tttattcaca gtgctgttag tataaattca caacctttgt atttctttta tcgagatgtc 2028661 ttccctaacg tgctatacgc aatgcgctaa taaaaggttt caaaaatgac gttcttttat 2028721 tagataatac gctggctgaa aacgcctctc ctgattggcc aaagcgcgaa tgaaaaaagt 2028781 gcatgaatac ctgcccaaca gacagaataa gaagagttga tatttcaaca cttttcgtaa 2028841 aggggtgaaa ccaatgagta agaaaggtat tcaaaattca agtattgaac aaataagaaa 2028901 tgaccatgag actgaaacag cttttaaagc agatgatcct aaaaaacacg gttccgatcc 2028961 taaaagaacg aaataagttc ttacccccac taaaatatca ataatctgga ggaagtaaag 2029021 tgactcaaaa aaacggtgca gacagacctg atgattataa aagattttct tcattagaca 2029081 aggaatatga ttttcagcaa tctatacgca gcaatactga gacagaaagt gtaaacactg 2029141 aaacacaaac tcataacaaa gaaaacaaaa atgacacaac agatgttgcc gggaaatact 2029201 ttgagccctc agattataaa ggaagcacgc aattagaaaa aggattggct gaaactcatg 2029261 aacaggtcag cgatgactat tttgaaggga caatcgatca aaatttggac tagccataca 2029321 aacggaacta acttaaaaga agtcagttaa ctctgttttt agaaacaacc acagtaaaag 2029381 tagccaaccc ccaccgaata agatgggggt tgcacgtaag tagcctgttt aatatttaaa 2029441 acgattaatg acggtttgaa gttcttctgc caactgagat agagattctg cggcatagga 2029501 gatttccccc attgaatgaa gctgttcctg tgatgaattt gcaaccgctt ctgtatttgc 2029561 tgacgtttct tttgtaccag cagccaatgt atgaactgtg tgctgaatca cttcaacgcc 2029621 tgaagtaagc tgttgagttg ctgctgcaac ttcttgtatt tgagaagtga cctgttccac 2029681 caggttcagt atttcattga aatttcctgt tgtctcttga gaaagaacaa tacctgagct 2029741 cacattttct tgaacaactt taatattatt taccgtttct atcgattcgt tttggatggt 2029801 cgctaccacc gattggatgt ggtttgcaga tttatttgtt tcatccgcca acttccgaac 2029861 ttcttctgcc accacagcaa atccttttcc ttgctctccg gctctggccg cctcgatcgc 2029921 tgcatttagt gccaacaaat ttgtctgctc tgaaatcgtc gtgataagcg aagagatatc 2029981 gctgatttct gctgtgctcg ctaccaatgt ttgcaatcca ttgccggctg aatctacaga 2030041 tttatcaatg aatttcatct ggtctaacat cttgttgacg gacttagagc ctatttcagc 2030101 cttgtctctc atcgaagaag aaagatccgc tatgttccct gtatttgaag cgactgatga 2030161 tatactgtct aataattcag tgatggattc tgcgctcttt tctgtcattg agctttgctt 2030221 cacattgctg tcggcagcca tctgcatggc tcgtgaaata tgttcagatg ttgatttcga 2030281 ttcttccgcg cttgccgata attcttcaga ggaagcggcg acttgttcag atgagctgct 2030341 gatctgcttc acaatttgag ttaatgaatg agtaaaagaa ttaaaagatt gggcaagctg 2030401 gccaaattca tctttatttt tcacaatgac ttttttggtt aaatcagcct cgccgtgtgc 2030461 aatttcctcc agctgcttat ttatgcttct tagtggcacc ataatggact ttaacagcat 2030521 tatgcttaga acaatgccta atattactga tatccctgtg acaatgataa tgagcgattg 2030581 actcattttc ccattgccct gtatttcatc ctttagatcc tctacctctt gatccaggcg 2030641 atcagacagc ttattgacag ccggagctac gccttctttt cttattgttc tttcttctcc 2030701 aaaatggatg gtttctgctt ttttaggatt tgaagagtag gctgttacta cttgctgatt 2030761 caaagctcta tactgagtaa aacttgtctt aatgtcttca atattggatt gatacttctc 2030821 ttcatcaatc aagtcattaa cccggtcaag gctctttaag acatcgtctg cttttccctt 2030881 cataccctcg tcgtattctt tgtctctggt aatcaagaag cctctttcat catttgataa 2030941 cccggtcaat tcatattgga tgtgttttat ctctttttgg aattccattt tgtctttaag 2031001 ttcttcattc tttttcacag tagaagaaat cataaatact gaggagcctc caattccaat 2031061 aattgaaaca actaatattg atataatccc cagcaatttt gttttcactt tcatgtgtcg 2031121 ttttcccttt ccgcacaatg taatggctga aataaaatat gttcaagcgc gtttgaatcc 2031181 aattcgctta cgctcatgtc cataatatcg acacgtgtta tcaagtttta tagtgatatt 2031241 cttatatgaa taagcaaatt ctttacgtct ctgaacttac agaaaaacct taagtaaaat 2031301 ttgcagtctt ttgcggtatg taagtcactc ttattcgttt ttctaaaaaa ggcttttccc 2031361 acctcaaatt ggctgaaccg gctgttttct cgaaaatata atacaatacg cagcataata 2031421 tgaaggagcg aaacttaaat ggggatcatc aatggtaaag aattcattga ccgattgaat 2031481 aaactagaaa acgaaatatg gtatgatggc gaaaaaataa agggtaacat ttctgagcat 2031541 cctgcattta aaggaataat caaaacaaaa agctcacttt atgaattgca aacaaaggat 2031601 gagttaatac atgaaatgac ttattgcctt cctggagatc ataatcgaat cggcctttcc 2031661 tatctccagc ctaaaacaaa aaatgatttg aaaaaaagaa ggaccatgat tgaacattgg 2031721 gctagacata ctcatggaat gatggggaga agtccggatt acatgaatac ggttatgatg 2031781 agctttgctt cgtcagcgga gcttctaaaa gataaagaga attgctttcc tgaacatata 2031841 ctagatatgt atgaacaagc tgctaagcat gacctttcct ttacccatac attcattact 2031901 ccgcaagtga accggtcaca gtcctatttt gggctaagtg aaaaaccgat atctgctaaa 2031961 gtcattgata gaaccgaaaa aggtttaatg attcatggcg cacgactgct tgccacacaa 2032021 ggcgggttga ccgatgaaat cttggttttt tcagcgccta aatttttctt tgaaacagat 2032081 gaagcttatg ctttttcaat cccttctaat acaaaaggcg taaaattcat cacaagagaa 2032141 tcatttgtat taagcgactc ttcctttaat catcccttaa gctcaaggta tgaagaaatg 2032201 gattcaattg tggtttttga tcatgtgtta gtgccgtgga atcgtgtgtt tttttacgat 2032261 aatgtggaag cagctaaaga ttttatgaca aaaagctctt ttcatgcctt tacctttcac 2032321 caggttgtca ttaggcaaat gataaaaatt gaatttctat taggtgttgc acagcttctt 2032381 gtcgacacca ttaatgtttc cgaatatcag cacatccaag aaaagctctc agaaatcatt 2032441 gtgggattgg aaacaatcaa agccctcatt gacaaatcgg aaaatgatgc tcagttagat 2032501 gaattcggct atatgcgccc ctgtttaatt cctcttcaag tcatcagtac gatcattcct 2032561 aagctatatc ctcgatttac tgaaatcata caattaattg gagctagcgg aatggtgaca 2032621 ctgcctaccg aaaatgcatt tgactcagag atacgggaag atcttgacca atatcttcaa 2032681 gcaaccaata caaatgctga agaacgtgtg aaaattttcc gtttggcatg ggatttaaca 2032741 atgagttcat tcggaactag acaaactcac tacgaaagat attttttcgg agatcctatt 2032801 cggatttcaa gcaggctgta taccagttat ccaaagcagg agcagttgaa catgattaaa 2032861 acatttttac atgcagatac agaacattga aaaaacagcg ggaaaagatc cgctgtttcg 2032921 tattttttat tcaggaaact gaacatggcc cggtactgta taggctttgg acgttccgct 2032981 ttcaggcagc tttggaatgg tgtctttcac aacttttccg cggatgtcag tcattctgac 2033041 tttgagagag ccagtaccta aattcgtact cacaaaatgg ttatagtcca ttttctccat 2033101 gttgatccac ttaccatcct tttcatattc cattttcata acaggatact tgtgatttct 2033161 gacttggatt gctgcccacc acctgctgct gccttctttg atccggtacg tgaaattgcc 2033221 ggtgattggg gctttgacaa cacgccattt aatattgatt tttccgtctt tcatattgcc 2033281 gattttacgg aaggcattag gtgacagatc aagagctccc cgagcgcctt cgggataaag 2033341 atcagtaaca tatacggttg ttttcccttt tggcccttca acttccaaat aagagccggc 2033401 aagtgccgct tttactcctc cgtaattgag atccgccgga tttattgcag taatctccat 2033461 atcggaagga atgggatcca gcaggaaagc tcctcctgaa tagcctgacc ctgtatacgt 2033521 tgcataacct tcatgcaggt cgtcatatgc tgccgaagct tgcggggaaa aacagaagat 2033581 cgtcaacaaa accataccaa caaatgcact catgatcttt ttcatatttg gtcctcctca 2033641 aaccagactt caaatgagaa tcattatcat tataagactc aatccatctg gtttgaaaga 2033701 ggaaatagat tcatagttga ttttaaggca aattcactat cattcatata tcaaatgtag 2033761 gtacttatga aaaagccaat acaaatgaac gaatgtgcac ttcagccgaa tgtcttattt 2033821 ttccctctca aaattcgcat ttcaataacg aaatgaaaca ggctgttggc ctgataacag 2033881 ctatacagga aaagctattt ttccccgctc agtttcaact tagctgtcat catgatgcca 2033941 aagatcagca caatcggaac ccaaataatg aagtgataaa aatcaggctc agccagagca 2034001 acaataatag cccctacaca atacaaaata atagccagtg ctcttaacac agtatctctt 2034061 aagaaagtct tcttttgctt cttaaaaaac aaacggccgg atatatcctc taaaagagaa 2034121 gccaaagtgc cggtcaacac agttgaagaa atacctgcaa tccccagttt ttttgctgct 2034181 gtagtttgaa tccccataga aatgctcatg agtataatta gaatgtgcac aggaacaaat 2034241 gcccggtaaa aagaaagaca agcaaagaca aacaaaatga atgcttcaag tgcgagggct 2034301 tttgtcacag cagaaggcca aagggtattt tccgcctttc cgaccatcaa tgtagcaatg 2034361 atcacgccgc atataaatcc gattagcgca gtcaaggaat taaaaacagt gacctgaatg 2034421 gatttgccga tagctaaccc caataataca atgtttccag tcatattagc tgtgaacaca 2034481 tgtcccaggc ttaaataccc gattacatcc acgattccag ctgttaaaca taaaagtgat 2034541 agcaaggtgt ttcgataagc tgctgcagtc aacggtgtat caatcctttc ttctatttca 2034601 attgttagta tgtcttttgg cgcaatctct attttttaag taacccaaca ttaattagga 2034661 agatagaacc tattattcct ttccattaac tgtaataata atccccgcaa ggaaatgatt 2034721 aaaattgaaa ggaagcatat tgtgatgaaa cgactttgtt tatggttcac cgtctttagc 2034781 ttgtttttgg ttctcttgcc tggaaaagca ttaggtgcag tcgattttcc gaatacctca 2034841 acaaatggcc ttttaggttt tgccggaaat gccaaaaatg aaaaaggcat ctctaaaacg 2034901 ggcacaacgg gtggaaaaaa cgggcagatt gtttacattc aaagcgtaaa tgatttaaaa 2034961 acccatctag gaggatccac tccgaaaatt ttagtgcttc aaaatgatct ttccgcatct 2035021 gcgaaaacaa cagttaccat tggctcaaat aaaacactcg tgggctctta cgcgaaaaaa 2035081 acgctgaaaa atatttattt aacaacttca tcagcttttg gaaatgtcat ttttcaaaat 2035141 ttaacgtttg aacacagtcc gcagattaac ggaaataatg atatccagct ttatttagat 2035201 tccggtatga actattggat tgatcacgtc acattctcag gtcatagcta taatgcaagc 2035261 ggaagcgatt tggacaaact cgtgtatatc ggaaaatccg cagattatat cacgatcagc 2035321 aactcaaaat ttgcgaatca taaatacggt ttgattttag gatacccgga tgattctcag 2035381 catcaatatg acggctaccc ccacatgaca atcgccaata attattttga gaacttgtat 2035441 gttagaggcc caggtctgat gagatacggt tactttcatg ttaaaaacaa ttacagcaat 2035501 aattttaacc aggcgattac aattgctaca aaagcaaaaa tatattccga atataattac 2035561 tttgggaaag gcagtgaaaa aggcggcatc cttgacgaca agggcactgg ttatttcaaa 2035621 gacataggca gctatccatc actcaacaag caaacctctc cgctgacttc ttggaatcct 2035681 gggtcaaact atagctatcg tgtccaaacg ccggaatata caaaagaatt tgtcacgaaa 2035741 tatgccggat cacaaagtac aactctggta tttggctact gatataaaag aggccctgcg 2035801 ttaaaaacgc tgtgcctctt tttatactat aggctatttt taagcgatcc ttgtaattcc 2035861 atcaagatcc agcgtcggtc aaactaaaaa gcatatgttc ttttccacaa taacttctta 2035921 actggctttc ttattatacc agtttatcgc aagtgaaaag aaatcattgt tctgaacctg 2035981 tattaaatga acgatcgtcc cacaaactac ttaaaaaccc ctaaaaagga tgatggatat 2036041 gtgcggcagg tttactttgt actctgcatt tgatgatatt attgaccagt ttgacatcga 2036101 tcaatttttt cctaaaggtg aataccagcc aagctataat gtcgcaccat cacaaaacat 2036161 ccttgcaatc atcaatgatg gatcaaataa tcgcttaggc aagcttagat ggggacttat 2036221 tccaccttgg gcaaaagatg aaaagatcgg ttataaaatg atcaatgctc gagccgaaac 2036281 aattaccgag aaaccggcct ttcgaagacc gcttgtcagc aaacgctgca tcataccagc 2036341 agacagtttt tatgaatgga aacggcttga ttccaaaacc aaaatcccaa tgcggatcaa 2036401 attgaaatca tctgctcttt ttgcgtttgc tggcttatat gaaaagtgga gcacacatca 2036461 aggataccct ctttatacct gcaccatcat aacaactgag cctaatgagt tcatgaaaga 2036521 tatacacgac cgaatgccgg ttatattggc ccatgatcat gaaaaggagt ggcttaaccc 2036581 caaaaataca agccctgatt atctgcaaag tttgctgctg ccttatgatg ctgatgacat 2036641 ggaagcatac caggtttcat cattagtaaa ttcacccaaa aataattcag ctgagcttct 2036701 tgatgcagaa aatcatatgt agtgattgaa aaaattctct agcaagaact tgtcaaatag 2036761 ctttgttcct taggtgccaa tccctctagt aattatgaat atttagtaca tagatcaatt 2036821 agttatcttt agcatcagtt tgaaataatt ttattatgta aacttaaata agcaatgtta 2036881 ttcctttcat ataaaatagt ttacattttt ataaaatcgc ttcacttttc tattttgtca 2036941 gcaaaaaaac tgaaccacat taaacttatg aaacctgccg cacctgtgga ttgcaaatat 2037001 gatataagcc catagaggta aatccataca ctttccctcc taagaattaa atgaaatttc 2037061 tttcatctta catgaaggtc ttctttcttt tgtttatcca gtgtaatact taataatatg 2037121 ttgatgaatg cagctggaaa atatataaat cccactccaa gaatgcctag tatcgtactt 2037181 aaacttacta tgtaattctt tgtcatcgtt tgactgtcaa tcaatattag aagtgaaatc 2037241 aatccagcta aaacacctat aaaccaagca tcgccaacag cataagaatc atccagcatc 2037301 cctaaccatc gccccaatat agagctccca atggcagtca aactggataa aaatatgagt 2037361 gctttcattt cttctcctcc tttaaagcca atcaaactgg tagaaatcgg ccattgaatc 2037421 cccattatcg aatggttacc atttcatttc cacattaaca ttttaaagct cattacaata 2037481 cgattcaagc agaaaaaccc tacataacgt atatataggg atttaataaa acacaggcca 2037541 aaattcagct ctatctactt taaaaagata tgaagggcag ctgtgtgatc tgttacgtct 2037601 ttacgtaccg ggatatttca caacaggcac tttcttcttg cgcagagaat caagcatgac 2037661 tgatccagca ttcaagttgc tttgtactaa ttctttaggc gtcaatgcca tccactgatt 2037721 gagtgacaca tctgcatagc ggttactttt gaacatttct aaaaaccata atgtttctgt 2037781 accagtgttt tgtatatagt gtccggcatt agaaggcacg tatccaacgt cgcctgctct 2037841 ataatcaaat gtgcgggcag tcccatttcc gataaatacc gtcattcgtc cctgtcctgt 2037901 tagataatat tgccactcat cgctattggg atgccaatga agctctctca tcgcgccagg 2037961 ctcaatctga acaagtgcag cggctatcgt ttttgaaatt gggaagttag aagaatccac 2038021 aattcgtaca ctcccccctg gcatttgaat tgggggttga tttaacagct cgtgtttaaa 2038081 ggtcatgggg acttttccat atggtgactg aatgtcttca ctggcgactg atcccggcac 2038141 attcccttgg tagatataga cttgctcaga cggaagagag ttgaaagcat tctccgggac 2038201 accgaaattt gcagacagaa catcttttgg tgtgtgtgca agccaatctg aaatggttaa 2038261 cgttgaaaac tcagaaaagt tcccatcatc gaaaacgagc agaaactcgc agtgttccaa 2038321 tccctgtatg gaatgcggaa ttcctgccgg gaagtaccaa aggtcgccgg gaccaacatc 2038381 agcaatgaaa tttcgtccgt cttggtcaac agcggtgata cgtgcccgtc ccaaaagcat 2038441 ataagcccac tccgcttgct tatgccaatg aagctcgcgg acgcctcccg cagttaagct 2038501 catgtttaca cctgcaatcg cagtcgaaat cggaagctgt cttacggtga tttctcttga 2038561 ccagccgccg tgatctaatt tcatgggagc gtctgagaat gaaaatctca agttaggaat 2038621 cataccctca tctgtaacag gcggaacaaa tatattcgga ttttgaatat cccgtattat 2038681 atttcgcggg cctgtatcaa tagctccagc tccatcactt cgaataggct gcggcacgtt 2038741 tctgtcttca tgattgattg gttgttgttc caacagcatg cacctcgttt tagaaatgaa 2038801 caagatttta tttcagccta tgcagaatct tagattgctg tgcctaggaa tccgcaaata 2038861 aaaaagtgac caccaatgtg atcacaaata catcaaataa actatttttt ataccatggc 2038921 ttcttatgta atttgattgc ttctgtctgt tttttctggc ctgtcctcca ctccactttt 2038981 actaatacat catgacctat cacttcatct tcaggcatat aatcaaaggt ggaaatatgg 2039041 tcctccatgc gtcccccacc cggcatttca tcacctgtgt actccgataa gtcgtactca 2039101 tctacgttat catcttgata cttttcgcca tctacataca gagtaattct ttcaacaaca 2039161 gtccactttt cttccttctt actcccctgc caatatagat ttagaaaata attgggtcca 2039221 attgaagttt tgtctgattt ttcaaggtta gacatccaca gtccgctttt cccgctgccc 2039281 tcatatttca ctttgttccc tgacaccatt acaaataatg tgatgatgca gatgatcaag 2039341 aatccagcaa tgatcaatag ccatttctta atattgttct tttttctcat gtttttcctc 2039401 actttcctaa ctttttagta ggaaaatacg atcaaaatgt taccgaaaag aaaataagaa 2039461 agggctaatg atctaacaga tgactgtcta aacttttgac ttaaattaaa gtgctttcta 2039521 aagacaagat taaaacgtat aacagctctt aaatgcattt tttgtttcat tgagtcaaga 2039581 accttaaaat ggctttttat tattaaaaat caagctagtg tattaagtaa cttttcaaat 2039641 ttatttatac tcatgatctc gtgagtcaca aatctcccat caaaaaaaac gctaaaagtt 2039701 gtccaaatag ctggtgactt ttgtgcctct tctttcgatg ataactgaat tgactgaaat 2039761 tgaacccctt tcttttcagt caattcccgc aaatcattta tcatgcccac tgcaaacgga 2039821 cactgagctg tatagtatat cgtaatcccc ttttcattga tagaatcact tttcacctgg 2039881 ctcttaaatg caggagaatc tgcaaggcca ttccaagtca aagccattaa ttgaaaataa 2039941 ggggcagctt catcttgtag agtaaacccc atatgctcaa agaaatgctt atcacttaaa 2040001 tagggcagtt ttttcttgcc tgcgatatgg ataatgccat ccatgccgca cgctttcgca 2040061 tctgctatac atttgtccaa caatcgtttc gcatgaccgt tatttttata tctgccagac 2040121 acccacagac aattaatgta cataaaatta ggcgcattga taggcaccca tgcctcattc 2040181 gcaggtaggt attcaataaa gacttttgcc cgttcatgta agcgatagaa caccaatcct 2040241 tcatccattc gagctttgag ccatctcttc ttttcattaa ctgcatgctc atattgtttc 2040301 gtgcttaatg cacagcaaat atgattgtct tcaatattgt cctttgtgat ttcaatgtag 2040361 cacatctcct ctttcccccc tttaacataa ttacatggaa ttcaacttca cactttacat 2040421 gcctaataga ataaataccc gttccaactt aaatactttt tcttttccat tttgccaatt 2040481 aactgtaaaa cccttctttt attcagatat tatcttgatt cctatatcac ccatttcaaa 2040541 tccaaagtgt gttcatcttt gaggattaga tgcactgctt atgctataaa tacagtacac 2040601 gaagtttttt atttgaagta atatttgtta cgggacagca atagtaaata agtgataaaa 2040661 ggggaattaa acttggtgga aaaatgttat tcttgtttaa tttgcggata caaaggatta 2040721 attcaaaatc ctttgtataa aggcgagtat caaaaaacgt ttgacatttg tccatgttgc 2040781 ggttttgaat ttggctacag tgaggatcat gatgtgaggt taggttttat tgtaactcct 2040841 gatcatttaa ttgaggctgc atttcaattg tatcgcaaac aatggcttga gagcgggatg 2040901 gtaattgctc atccggaaga tattccagaa gaattgaaaa atggcaattg cttaaaattt 2040961 gaagttttgt tgaaacaatt gaaaaaacta aatcttgaca tagaaaattt tgaaattagc 2041021 ggtttttaat gatgaaacag gttgcacttg tttaggtttc actgtcatta tcagtaaaat 2041081 gttaagttga aatgcgcaat cagtcacaaa gtctctattc gtattcaata aagactttgt 2041141 gatcatcgac aaacatttca ctcccatcgg ataaagtatc caaaaggcct cctctggttc 2041201 ttctctatag tcattaatca cagtcacttt gacatttgac tcagctatga ttggttttcc 2041261 aacaattttt cgttttttcc tcaggcaaag taagagatcg aatcatcaaa gccattccat 2041321 ctttactgtc taattaacgc catcttcagt gaatttaaag gtctgtttta aattgcgtcc 2041381 ttcttgcccc ttctgtgtcc aaattataac aacctctaat tcagaggcct tatctgccag 2041441 cataaaatga ttgaacttca gcggtgagcc atcatttaaa ctttcagcta acattttaga 2041501 atcttctttt ggtttgacac aattttcatc gggacatcca aaaagcgaaa accttgtgat 2041561 tgaattaggg tcatttctat acaattgcac atccactgta gctgcttttt cccctatatt 2041621 tttgacttcc aaggaatata cttgatattc tcctttatga ggtctcgtaa attcctttac 2041681 attttttgct tcacttactt ttactgacca ctggtctgtt ttttgtgtaa taggcaacac 2041741 cgtaaaagtc agggcatgcg cttttgattg gcaaaacgta aatccaactg ctgtaaaaac 2041801 aattacagaa aataataccc ttttcacttc atttatccct ccttcctttc actggccgct 2041861 ccttaaagaa ttgattttga gcaatctaca agctctctta accaaaacct tacctgaggt 2041921 tttgtcttta ctgctctgca tttatttctt tcggtatccg agaaggagct ttggggattt 2041981 ttctcaatct gctgttaatc acatcagaag agtatagcgt aataatcata cttcccccat 2042041 acctttttgc ccgaattaag attggttggt tatattggtt ttgaaagcga aagtcaggac 2042101 ctccccagct taccgtcgca tcccgtccgg gcggtacata tggtacactt ctagtatgag 2042161 aatagcgctg aacgatctgc agtcctgcac gatctactgc attaaataga gttgaggaca 2042221 cctgacaaat tcctcctcct acaccttcag acaactcccc ttttacaata atgggtgcac 2042281 ttttatatcc tttgttccga gttctcattc ccacaacttg gttaaacgaa aacgtctcat 2042341 tagggaaaac aacgtgattg tcgattgctt ttgcagaaag agaaatattg tgtgaacggc 2042401 ttttattgct tgagttaaaa tacgtcacgt actgaccaag ctgctgcgta ctgatgtgag 2042461 ctagcagctc gctgtcaact ttcggataaa tgttcatttc cggcacttct atcttggagg 2042521 gaccttgccc ataaaaatac gcataaaact tttccataaa cgcctgttga tacagtttgt 2042581 agccaaccct gcccgggacg atgcttccat gatcgttaag gacagcattt atcggctcac 2042641 ggtacacttt ctgatcaagc tgtttgatga atttactgta tttttcatag tcaaccattg 2042701 gagtgccggg aagaggcatt gtaaagtctt cacggttaac agtggcaatc gtccgtcctt 2042761 gctgtgtgac cgttaaactg tcctgcggct cactcggctg agccaataaa aaaagaccag 2042821 tgatcaaaat ttgtatcata agtcggttta cctcccaatc attagtatga acagccgctt 2042881 atcctttgat gtatttcttc ccatcgtttg tttgaatctt tagacgttga taaaaacctt 2042941 cataaaagag cttagcttta tgttcacacc gatccctgag ctcactgagg cacacggttc 2043001 attcagtcgg caagtttgaa gtagttcagc atctcccagt gatgagggat gcttttttgt 2043061 cttgtcaaaa atgaaaaggg tctcctataa caacaaaaaa tcaatccatt tcaatatttt 2043121 tttattgaga aacgataaat tttttgttac attcaattag acaacaaata aatgaggtgc 2043181 ttgttatgaa tcgaatgtcg acaatttttt taaagatagc tttggttctt attggaattc 2043241 caattcttgc tttatgcatt tttttagtgc ctaaggtagc caactattca gcagaattat 2043301 ttccaaatat cgcttatata aaatatctcg ttttcatcta tttgtatgta acggcgatac 2043361 ctttttactt tgctctttat caagcgttca aacttttaag ctatattgac aaaaacaaag 2043421 ctttctcggg tttgtctgta agagctttga agaatataaa atattgcgca gtcactatca 2043481 gtatctttta cgcagcaggc atgcctgtct tttatctgat ggccgagata gacgacgccc 2043541 cgggtatcat tgtgatcgga ttggttatta tttttgcttc aatggtgatt gcggtctttg 2043601 ctgctgttct tcaaaaactg ttaaaagaag cgattgatat aaaatcagaa aatgacttaa 2043661 cggtctgagg tgatgacatg gcgattatta tcaacattga tgtgatgctt gctaagagga 2043721 aaatgagcgt aacagagctt tcagagagag ttggcatcac catggctaat ctttcgatat 2043781 taaaaaacgg aaaagcaaag gctattcgat tatcaacttt agaagcgatt tgcaaggctt 2043841 tagaatgtca gcccggggat atattggaat accgaagtga tgaagacaca ggattcgtaa 2043901 agaaaaaata tgaaggatca acagaaaaat aaagtgattg gcggtgagct tatggacata 2043961 aacttatatc catctagctg ctatactaag cgtccctttc atacacgaag aacacaacta 2044021 tggaggaggc atacatcatg agagccataa aacaaatcgt ccattttggc tgggaacaag 2044081 ccctttcatg tttgtttcct gccgttattt ttgcctcttt ggctattacg caaatcatcc 2044141 cactgccctt cttgccgcgg tatgactggc tgctcattat ctgcgttctc atgcaattgt 2044201 ggatggtgcg ttccggtctt gagacacggg atgaattaaa agtgatcaca ttattccacc 2044261 ttattgggct tgctctggaa ctttttaaag tccatatggg ctcctggtct tatccagaag 2044321 aaggatactc caaaatattt ggagtacctt tgtatagcgg ctttatgtac gcaagtgtag 2044381 ccagttattt gtgccaggca tggagaaggc ttaaggttga actggttaag tggccgtctt 2044441 tttttgcagt tgttccgctt gccgcagcga tttatttgaa ttttttcacc caccattttt 2044501 ctatagacat tcgatggtgg ttatcagggc ttgtcatcat tgtcttttgg caaacatggg 2044561 ttacatacga ggtgaatgga gctcgttacc gtatgccgct cgcactttct tttatactca 2044621 tcggattttt tatatggata gcggaaaata tcgctacgtt ttttggagct tggaaatatc 2044681 caaaccaaat cgatacatgg agtctcgtac accttggaaa ggtaagttca tggctcttgc 2044741 tagtgattgt tagctttctt atagtagcat cattaaaaca agttaaggag cagagtccca 2044801 caaaggcaga gatggatgaa tctttttctt agcatacgca tacaagctcc caaatagagt 2044861 gaaaagcaac gttcaaatgg ttgctttttt cttttatgta actctgccgg tgagtattca 2044921 tcttcttcaa atttcatcgc aacacgataa ctgattcaga ttacaactgc tttcaacact 2044981 ttgacaaact catgcgccgc cggcgttatc tcttcaaatg aatgtgcgat gacgccaata 2045041 tcgcgtgtga ccctaggaaa gatgtccttt ttaatcaatt gatgcgggac ggatgaaagt 2045101 gtaaagtttg aaatgatgcc gatacccaag ttatttttga ccatattaat caaggtttcg 2045161 gcattttgca cagttaagtt ttcctttaat tcgatgttgt attgcgaaaa tgcgtttgac 2045221 atcgcgattt catgaccgcc tttacaaaaa atgaggtcat cttgatatgt ttcaaggtcg 2045281 acatgctttt caagttttaa ttcgtcacgc tgcggcggga tgacggccac catatagtcg 2045341 ttacacaata gctgattttc aaacggttca aatggagatg ctgcgatccc gatatcaacc 2045401 gtccgatctt caacccatcc ttttatttgg tcagaggttc cttcgatcaa ttctatgcgg 2045461 atcagcgggt agtttgatct gaatgccgca atcgcctgtg gcatgatatt tgttgaaact 2045521 gcaggaaatg aaccaatttt caccttcccg tttaacagct tgttttcccg gttggctact 2045581 tgatatattt tgctttcaat tcccttcatt tgcctcgcca gcagcaatat ttcttttccg 2045641 atgtcagtca gcattaaacc atgatgttta tccctgatca ataatttgag ctgcagtgag 2045701 ctctccaggt tttttatcgc tttacttacc gccggctgag agatgaacaa ttcttttgcc 2045761 gcttctgtaa tatttaattt ctccccaact tttacaaata tgtgaagatg gttcatgttc 2045821 ataaccattt ggttataccc ccaataataa aaatgtattt cagttataca taaatgtaac 2045881 atatgataga aaccagcacg atattttaac aagaaaggcg gcttcattat ggtaaaagtt 2045941 atgctgggaa tcatatctgt cacacttatt tggggttata cttgggttgc gatgaaagta 2046001 ggaattcatg acatcccccc gcttttattt tcgggtttgc gcctgttcat cggagcagtt 2046061 cctttatttc tcattctctt catccaaaga aaaaagcttt caattcaaaa agaacatctc 2046121 aaaagctata tcatcatgag cctgttgatg gggctgggct atatggggat tttgacgtat 2046181 ggaatgcagt ttgtcgattc agggaaaacc tctgttttgg tatatacaat gcctatattt 2046241 gttacggtga tcagccattt ttcattaaac gagaaaatga atgtgtataa aacgatggga 2046301 ctggtctgcg gcctcttcgg actgttattt atatttggaa aggaaatgct caatatcgat 2046361 caaagcgctt tatttgggga gctgtgcgta cttgtggcag cgcttagctg gggaatcgcg 2046421 aatgtgttca gcaagctaca attcaagcat atcgatatta ttcacatgaa tgcctggcac 2046481 cttatgatgg gagccgtcat gttattggtg ttttccttta tatttgaggc ggtcccttca 2046541 gccgagtgga catatcaggc ggtgtggtca ttgctgttta atggcttgct ttccaccggc 2046601 tttacctttg tcgtatggtt ttgggtgctc aatcaaatcc aagcgtcaaa agcatccatg 2046661 gcattaatgt ttgttcccgt attggcccta ttctttggat ggctgcaatt gcacgaacag 2046721 atcaccatca atattatcct cggcgcactg ctgatatgct gcgggatttt tatgaataca 2046781 tttacatttt cacgacggaa agtgtgaatg atatacattt cccctgtcat ttgggcttca 2046841 tgtgacagga gaagactatt acgagaaagt cttctagaat cctgacgaca gcctattaaa 2046901 caatgaaaaa agctaatgtc tgcatgtaga cattagcttg gctggcgttt aggctggtga 2046961 gaatccagat acttttttat taccattctg gctgatcaaa ctgaaaaccg tatagacctt 2047021 ttactttaac atctccgcaa tctggatctt ttgtcaaaat caaataatga gtcttataag 2047081 gcatcgtctc aactcgatca gttgcactaa aatcaaaatg atcccccgag aagttttttt 2047141 cactaacggt tatttcatat cctgacaaag tcattcgcat gattcttgcg ttaattgtac 2047201 atccttcagt atcgaaaatg gtgaatctgt acccaaagtg agatgtccaa tggtttgaat 2047261 ttaggtcatc agacttcata aaccattttt cattctctgt cattgtaaaa ctcactttct 2047321 cctcatcttt cacgataacg gccgaagctt cccctacatg gatagtcaaa gccaaaagaa 2047381 atgtaaaagc taacatcaac atctttttca aaagagttcc tcccgatatc ttttacttca 2047441 atatattgga agggtctttt ctgatcaaga cagtcttctc caaatgaatc tttagcacca 2047501 tgaaatgagc cttaataaga acagttttaa cccaaatcaa cctctattcg aaataaggct 2047561 taccaatcta tattcttttt aaaagtttct gcatttcttt atttagctcc tagacacata 2047621 taaaaaatgc tcctataagt tcaggagcac tacaaaaaac tgctaaagtg ttttctatcg 2047681 atttattgta ttcattagct caaagaaata ttcaggcttt tgagtcttat ttagcttata 2047741 ccatgaacgc aatgtatctg gtgcaaatac atctaatttt ttcaatactt ctaccgcaaa 2047801 ttccagagga gcaattcctg atgcagtaac caaattttca tcagatactg caggcccctt 2047861 ttcatagaat gtttctcctt tgtaattagg gcagaccata ttcatatagt cgaggtcatt 2047921 gcttgtgtgc tttctcgaat ttaagtatcc ttcattcgcg aggcccaagg ttgccccaca 2047981 aattgcagca atagtcgtgc cgagctttaa agcgtcgcca acttttttca agatcggctg 2048041 atgaatatct tctccccaag tgtttcctcc gggtaaaatg ataagatctt gactcccaag 2048101 agtacattcg tcaagagaaa tatctggttt tatgcttaat cctcccaacg tagttatcat 2048161 ttctttatta acccctactg taactacttt taaagatgct gcatcttgtt taaagtatct 2048221 ccctgagttt agttccgcaa ttaaatatcc atattcccag tctgacattg tgtgaaatac 2048281 gtagagataa acttttctcg tttgcatcca ataacactcc aatcacaatt gataaagctt 2048341 tctaatagat gactttgctg acagtcattg tcagcttttt tgttgattct attcttatgc 2048401 ccttgttctc ccaacttata aaaatataag atcaattgat tctatgttta ctagcgcaaa 2048461 ggggtttgtt acactaactg tcatgggaaa catttcaaag gtaatacaaa atcatttgaa 2048521 tgaggaggcc tgatgaagtt gaaaactaaa gcgtcaataa aattcggaat atgtgttggg 2048581 cttttatgtt taagcattac tggtttcaca ccttttttca actcaacaca tgccgaagca 2048641 aaatccatag aagacacaaa catggcaagc tgtataacga ataaaaaatt tgttcaactt 2048701 gagaaaaaat ttgatgccag gcttggtgtt tatgcaattg atataggttc aaacaagaca 2048761 atcgcctatc ggccgaatga acgatttgct tacgcatcaa cctataaagt tctagccgca 2048821 gctgctgtcc tgaagaaaaa ctcaattgaa aaacttaatg aagtcatcca ctacagcaag 2048881 gacgatcttg ttacatattc tccaatcaca gagaaacacc tagatacagg catgagccta 2048941 aaagaaatct cggaagcggc tatccgttac agcgataata ccgctgggaa catcttgttg 2049001 caacagcttg gcggccctaa aggttttgaa aagtcactga aacagattgg ggatcatgta 2049061 acgaaagcta aacgattcga gacggatcta aactctgcga ttcctggtga tattcgtgac 2049121 accagcaccg caaaagcact ggcaaccgat cttaaagcct tcactttaga taacactctc 2049181 acgactgaca aacgcatgat cttaaccgat tggatgcgag gcaatgctac tggtgacgaa 2049241 ctgattcggg caggcgctcc aataggatgg gaagtcggcg ataaatccgg agccggaagt 2049301 tacgggacac gaaacgacat tgctatcgtt tggccgccaa acagagctcc tattgttgtg 2049361 gcaattctgt caaaccgctt tacgaaagat gctaattatg ataatgctct tatcgctgag 2049421 gctgcaaaag tcgtccttaa cgatctcaaa taatatgttt agccttttgc cacaaaggaa 2049481 aagacattac ttttttaact tctaccgttc attttttgat gaacggttct ttcataagac 2049541 ctctagaatc atatatttaa acaccacaaa attaaacatt attataatta acagcaagtt 2049601 ttcattttat ggaacaagta aagtttgaat ctgacaagaa ttaagactaa gcaccctaaa 2049661 atccgttttc ttttcttcca agaatatact ccttagtgca agccattata aagatacaag 2049721 tgaacataca atgcagacaa ctctcttaag tctcttattc tgtgaccaat ttgtaatact 2049781 catgaatatc cggactcact tccaatattt cgtctcgttc gaagacacta acatatcaaa 2049841 ccacttgaat taacataact gaacttgata ttggtcactg gcagtttcaa tgcaatagaa 2049901 caacatttgt tgtctcagag gttatctata tgagaattca acaatttttt tataataatt 2049961 catatttttg tatcgttgca cttggtggat ttgactcttt tcgtgtatgg aaccacactt 2050021 ttattttttc acctcttttg agatcatctg tgttatcaat ctcacttaat cctacaatta 2050081 ctatgttatt tttaaacttg ttcataagtt gtccttcaga aagattgtaa tcttcttttc 2050141 ctggagcttt tgtatcggta atgagaattg ccctttcatt gtctttaagc acgacatagc 2050201 ctactaggct ctgcatcttt gtttcgtctc cgttttgttc atttttattg cagcctgcaa 2050261 ggaaaataat gagcataatg agcactatca agcttactcc gattttaggc atctttcttc 2050321 ctcctcttta aactcatctt taaaataaac aacaggatat cacccaaccc atctacttct 2050381 ttttgcaatt cataacagca gcatactcat tctccaattc ctcaaccttc tttttattct 2050441 ttctcaaata tttgcatgtg gtagccctcg atattatccg cttactcatt tttgcgcttt 2050501 caaatatatt attgaaggcc gcttctttct ggattccagc ataaatatac ttatccttac 2050561 tgtcgtttac tatcgcaact tccattaaaa tcgagatttt tacttttttt atgatccatt 2050621 attcacttcc aaaataactt ccaattacaa cataatatat gtataaattg taaatggagt 2050681 tgatgtaatt gaagattagg aaaatcttat tgagttctgc tttatccttt ggcatgctaa 2050741 tatccgcggt tcccgcattg gctgctggca cttcgtctga ggttgcagta aaaaatgaag 2050801 aatatgatta tgacactata taccgcatta gtcctctgcc aatggacttc cagccaacaa 2050861 tagaatacaa cggttatact tatacgctta cacgtcatta ttttgattac tcaatcgggt 2050921 tttacacggc tatttataca aaagttgttt aaacttataa aggagctttt tagctccttt 2050981 ttctcttgtt ttaagcaagg tatttctttc tatgtggtcc cctatcaaat acaacatcaa 2051041 cattctccag ttctctttga cacgaacaaa atctaaagtt tggttttaaa tgctggtaat 2051101 aaaaaattca ctttaaagaa gtgccgcccg caaaatacgg cttttgtaca ctacgccaat 2051161 tttatattga aaagccagac ctcctcaaag aggttccagc ttttcttaat gtgctatcga 2051221 tcttcgttag ttcaacggga actttatcat tcggtacaaa tgcagcctcc caacttctag 2051281 ttagggctga tggcggaata tctgacggtt ctctacacac atcagacatt agaagatttc 2051341 aatgtagcct tctgtaccat gaacgcgaat tcgttgccca tcttttatca gcttggcagc 2051401 attttcaacg ccaacaactg caggtaagcc atattcacgg gctataacag ctccatgggt 2051461 catcagcccc ccaacttcgg tgactaggcc ttttatggat acaaacaatg gtgtccagct 2051521 tggatcggta aaggaggtaa ctaatatatc tccatcttct aaatccgcat cttccatgtt 2051581 taaaatgaca cgcgctcgcc cctctataac tccggaggaa acaggtagac ctacaatcgc 2051641 tccggctggg agattttctc gtttatactc acctgtaacg atttcaccat cagacgtgat 2051701 aacacgtggt ggagatagtt tttcatataa tgtgtactcg tcttttcgtg tactgatgat 2051761 ttgataatcc agtttatgtg tgcgcacgac ttcgtgaagt tcttcaaaag tgagatagta 2051821 tatatcttct ttttcatgaa taacgcccgc ttctatgagt tgttcggctt ctttcagtaa 2051881 agcctgctta taaacgaagt atcgattaac catgccgtat tttggatatt ccctaaaccc 2051941 gctgaaattc cggatgatat ctatcgctcg ttttgtttct ttggcttttt gttcaccatc 2052001 cggtaattgc ttcaatcgat ctaataactc ttgttctttc ttcaaagctt cctgtcgccc 2052061 ttgctcaaat ttccgatggc cgacattagg ctcaaaattt ttaatattat taagaatcat 2052121 tgggacaagt gtagttggtt tttcgctcca tcgagttctt gtgatatcaa tctctccggt 2052181 acatcgcatt ccgtatttgc tgagataatc atagatcgcg tctcgggttt tgcttccgcc 2052241 atcaaactta gccagttcat ccaaaaagtt atcatctttt acatgttgta agtaatcaat 2052301 tacctctgga taaggacgaa tcacatctgc gacgtctaat agcgcaagac ccatttctga 2052361 agtaatatta tggggtacag attgagaaag cgtatctgct gcgttttttt cacctaacca 2052421 ctcgttcatt ttttcgttaa tccataatga agcattcata gcagttcgaa ttagaaccga 2052481 actttttggg ttaaataaaa tcttctttaa ttcctgaata tcttccagaa taaaacgaaa 2052541 taaatctgat cctgatttcg tttggatgtt ttgttttaac tcttctatcg atgtttgact 2052601 gctctcaatc aaatcagaca cgattgtcgg atcgttttca acttgagccg gcatatctgc 2052661 attgcctctg ctgggatttg gtgctgtttt atcatttggt atcgacttta tgaaatctcg 2052721 tcgctttatt atggtcataa gtgcgtcttt taagagctga tcgtgctgcc ccatgccttt 2052781 taagaaaact tctctgctgt caggggatgc cagatgatgt gtgacatcaa caaatagcct 2052841 tccaccggct ttacgcatgg gtgcaacagt cgtcaacaga aaaaaagaca atcccagtgg 2052901 ttttatggga tccgtcatca tttgttgatg accaacagaa atatagacgt gattttcttg 2052961 gtcactcgct tcagggatgg ggaataaagt agtgattgga cgactctgta caatataaaa 2053021 agtatcgcgg gccaaacacc attcgatatc ttgcggctgg ccgaaatgag cttcgatctg 2053081 tcttccaatg cgtgccagct gtaaaatttg ttcatcagtc agtgtttgag ccttttgctg 2053141 atcagaatcg atctgctgtg tttctgttcc gccttctttt cgtccgtaga tagccatttt 2053201 tttagttgct attctcttat cgatgatttg cccatcctgt actttaaaac aatcggcaga 2053261 taccaagcca gaaaccagtg cttcaccaag tccaaaaccg gcatcgatgg ataacacctt 2053321 tcggttggag gtaatcggat cagcggtaaa taaaatcccc gaagcctgag ggaaaaccat 2053381 cctttgaacg ataacggata aatagacttg gctgtggtca aatccatttt gcatacggta 2053441 aataaccgcg cgatccgtaa atagggacgc ccagcattta ctgatatgct gcaagattgc 2053501 atcgacgccg gtaatattta aataggtgtc ttgttgaccg gcaaaagaag catgtggtaa 2053561 atcctcagca gtcgcactag aacgcacggc ataggcatgt tcctcgccaa actgggagag 2053621 atattgagcc actgctttca caacatcgga aggaatgtct acttccataa tgatttgccg 2053681 aatcttccgg ctgatgttac caatctgatc tcggtcctca acttttagca tggtcaattg 2053741 atccaacaac acttgtaacg tttcgttttg ttcgatggct ttttgatatc ctactgttgt 2053801 gacacaaaat ccttctggta cttgtatacc ttgaattttt gataattccc ctaaatgtaa 2053861 cccttttcct ccaacgagcg aaagctgtgt tttttcaatt tcatgtaaac cgagaaccaa 2053921 agaactcatt ctacatctcc ccttcaaaaa aaaatattga caagagcttc ctagcaggat 2053981 ataataaaat tataagatgg atatctataa ctttttaact agaaagcgca cgtagtgtga 2054041 ttatatcacc gtgtctgttt ttgtgcaata taaaaagaac ctgggaaatt tcaccaggtt 2054101 cttttcttaa tttccatagc tagtcgcatt aaaaaacttg gtttgagctg attcaatcct 2054161 ctaaggaaat cctaaagttg ggttcttttt gaacttactt gctttgttcg tagagtcccc 2054221 attcataaat tggacttttt gttcttaaca gtcccacctt taactagtat aaagttatga 2054281 ggatctggtt aactactaga tatttttatt ttgaataagg cttatgtttg ataaagaagg 2054341 gttatgtaaa ggtgtctgtt gtgagcaagc gctgactaca aaaaattgat agcattctca 2054401 tttaaatacc attctattaa cctataggga aagttttaaa accagatgga gaatacccta 2054461 cctccagcaa ttccaaggcc gttcacctag tagaaaacaa cctttaacca ttactaacga 2054521 ttttaataat cattgattat aaaacttctc aaggaacgat cagcagcccg ttagctaccc 2054581 ctgattaagg atgatctgtt accacactgt tacgttagaa cttccactac tttgatatcc 2054641 ttctgtcgcc atgacttggt aagcccaatt actgcccaga ttcattccat ggctcttcca 2054701 tgcgttcaca tgattgctga aagtgattgt agcgttgctt ccggttggtc tcttcgactg 2054761 gcgaacactc cagtactgcg taaaagtagt gcgatcgcca tcaatggaag gtgcgttata 2054821 acgtgtagtt gtatatatgt catatgtacc cccatcactt tttacagtac ctttatacgt 2054881 tccagtaggt ctataagtac cccatgaatc cactacataa tattctatga gaggtgatct 2054941 cgtccaacca tataaagtta aatatccatt gccattcggc gcccaaactc cggcattata 2055001 gtttatcgtc ctaaatggcg aacctgtagt ccaaccttta ccaacaacaa aatttccggt 2055061 attagaccaa ttaacactgt aattcccgcc agacccattg acagcgttta ctataccgcc 2055121 cccatcagtc caattttgcc agtagtctgt gctagctgca gaggcggttg ccgaaaacaa 2055181 gctaatactc attaaagctg ccgataatcc aactaagaaa ttctttttaa acttaaacat 2055241 atgttacctc ctataatatt ttttccgact ttgaggtagc actcgtatac atttaaaaca 2055301 ttcttaatta ctaacgccaa agcttttgat cgtccccttc agtataatac cacgaattca 2055361 tgagcaaata ttaaaagtat ttgtaattca attacaaata cctagaaaca cattataagt 2055421 ggtcttcttc caccatatcc tgatcctttt ttcgcaggat cacaattctt gtttctaatt 2055481 cagatggagt aatatctgca atgaattccc attgaaccat ttcaaataaa ggagatatac 2055541 attagagatt gtgaaattat tgtagctgcc gcttgtctaa tgaagggaag caaatttatg 2055601 aagaatatga agaactgaag aagaaaacaa ttaaggttat actaagaaag aactgctcaa 2055661 ttaaaattat tgaccaaatt tgaggatgat agcttagatc agttttacaa agaagttgca 2055721 agatttttat ttgaaagggc tctgaaaaag aaaaaaaaga attgacaatc agggtaactg 2055781 tgggatgtaa ccgagcctcc aattcaaaat aaatatcttt aactttcttt ttttatttaa 2055841 agagggactg tatatccctc tttaaaatta agctttagat tgctgctgaa agtaataaaa 2055901 attgtacttt tgatcaaacc cttcttcgct accacaaaga aaaataatga attcaataaa 2055961 tgcgataata gaggggatac cagtccagca aaacaaaata tatagaatac cttgtcctac 2056021 tcttcccaaa taaaacttat gtattcccag acccccgaag aaaaatgcta ataatgccgc 2056081 tacaattttg ttcttcttgc ttaccatgac ttcctcctag ttcattgcta ccatttttaa 2056141 agtaatgctt tcacattata atgcattttc cgccagaaat cgtgaaaatt ttgaaattct 2056201 tttgagattt tttattttat tgagaaatga aagctcatat aattgaacta gatggttttg 2056261 ggaggcattt attcaaaatg tattgccaaa gattacggca attacgaaag gcacacaaat 2056321 taacaatgga acagttagct gagaaaattg gaattgcaaa atcaagttac ggcgggtatg 2056381 aagctgaaag caaaaaacca ccattggaca agttggttat tttagctaga ctatatgatg 2056441 tttcagttga ttacatactt ggattaacag atgatcctga tcctaaagtg gaaagaaaaa 2056501 atctaaaaga gtttttagaa aaaccagata ttcactggga tggatataaa cttacccctg 2056561 agatattaga tcctatacgg aaaattttga agttggttac tgcaaacaac aattaaaaaa 2056621 gccctcataa gggcttttgc ataaaacaat tatttcattg aattttctgg actcatttca 2056681 agaagtttat tcatgatgat agctaaactt tcaccagctt tttgtagctt ctcacctgct 2056741 tttatcagag taattaaagc acttaaaaag tccactaagc tattttgatt tattgcaact 2056801 gtttctttat aagctttgta agcttcttca aactgatcaa attgcacacc tttcatagca 2056861 acaacagcta atttatctga aatatttcca tatgactctg ttaaactaaa aaatcttttg 2056921 acattgatta gtaaggcaat gcactttaaa taatcgtgcc ccagaccaat atgtaaattg 2056981 cctgcagcaa acagcaaatc gttcaaaact gtgtacggtt caccattcct tgcaactgtc 2057041 tcaatccctt tgtataagta taataaaaag acaaatgaat ttttatctgt ggaacgctca 2057101 ggtaataagg acactataat aacttacttt aagccaaaac atccaaataa aaaggctggt 2057161 tataattatt ataaaaatca ataggaacta taaatatata aagagggatt gctatgccaa 2057221 aattatatac atgtttaatt tgcggatata aaggattaat tcaaaaccca ttaaacaatg 2057281 atggtgagta tcaaaaaaca tttgatatct gcccttgctg tgattttgaa tacggctaca 2057341 gtgaagatca tgacgtaagc ttaggtttta ttgtaactcc agattattta attgacgctg 2057401 caattcagtt ataccgaaaa cagtggattg agaatggaat gaaaactgca aatcctgaag 2057461 atattccaga agaattaaga aacggtgact gcttaaaatt cgaggtgttg ttaaagcaat 2057521 tgaatagcct aaatctcgat actgaaaact ttgaaatcaa gggatttaat ggttattaag 2057581 cagatccaag cccccatatg ggggcgttct tattattgta cagtctatca gaactattta 2057641 tagaaaaact atttaatgta ttgtataaat atcactgacc ttttctttct ccattcaact 2057701 tccttaaccc tcaactgttt gctgctgcat cacattcctc ctttttgatt tttgtgtatc 2057761 aagcctgtac aatattcaaa aaccctaaag gatgatgaac atgtgtggca agttcacttt 2057821 attttctgag tttgatgaca tcattgagca attcaacata gatcaattct tacctgaagg 2057881 tgaatatcac cctagctata atgtcgctcc ttcacaaaac atcctgacaa ttatcaacga 2057941 tggatctaat aaccgtctgg gtaaacttag atggggtctt atccctcctt gtgctaaaga 2058001 cgaaaagatc ggttataaaa tgattaatgc tcgtgctgaa acattggccg agaaacccag 2058061 ctttcgaaag ccgctcggaa gcaaacgttg tatcataccg gctgacagtt tttatgaatg 2058121 gaaacgcctt gatccaaaga ctaagattcc tatgcggatt aaacttaaat cgtcgaatct 2058181 ctttgctttt gccggcttat atgaaaagtg gaacacgcta gaaggcaatc tgttgtacac 2058241 ttgcacaatc atcacaataa agcctagtga gcttatggaa gacattcatg atcggatgcc 2058301 agttatccta actgatgaga acaaaaagga atggctaaat cctaaaaata ctgatcctga 2058361 ttatctacaa agcttgttgc tgccttatga tgctgatgac atggaagcat atcaggtatc 2058421 ttcattagtg aattcacctg agctcattga atcccattaa gtaccactgc catatcgctt 2058481 tatataccac ctcctcttag ctaatatgtt ctaagtagga ggtggtattt tgtttgtatc 2058541 tccaatgcta ttgcattcaa taaaagagcc ttttgatgac gagagctata tcactgagct 2058601 taaattatca agactaaaat taaaataagg gctcatacat agttgatata tataatatgt 2058661 attgagacct ttattgaaca aacgccccgt ttgttaaagt ggaaatctct ataattaata 2058721 gccgactttt aaaagttcca atctaaaatt atcctctaaa tcggctagct tcattaactt 2058781 ctccgatata cctttccaat ctttatttac agacatagaa tgacatatcc caaacacctt 2058841 agcctgttca gtcttcaaca ctgataaatg tgaatgccta tctttaaaat acattgcata 2058901 atcgttggcc cttcttgcac ttaattggaa aaggaagaat gttgtatgcc ttatagtatc 2058961 agctgtaata ggggcattta ataattgatc agcataaaaa caaattgctt cccttccaat 2059021 taaccctata tccacttttt cgaatttccg ataagttctc ttaaaataat caattgctct 2059081 ctcgtatatt tcgttattgt ctaatgtgac aacctttttt gctgtagacc aatatttatt 2059141 gattcctttc ctatacggaa tcctttccgc catccaagcc ttcttaaatt ggtccagtga 2059201 taatggaaca aatggaaagc ctgctggatc ttgcacataa atattttcat tatccatttg 2059261 gtaccctaga acataatggt cagaaccatt taaattttta tgattcggat ggtatgttag 2059321 ctcccccata tctaaagggc ctagaatgac agggttttgt ttgatttgct gttttaataa 2059381 cggaaatggg tcatctaagt cactagcttg ctgatgttct tctgcagtaa atccaaggat 2059441 gtttaaagca taattgatac catcatcagg atctctcata ctaaaataaa ggtttttttc 2059501 atattctatc atggcaccta acccaacacc agttaatatc tctacaagtt gaggagatac 2059561 attttctcct attgatgaaa gaaacattgc agttgaattt gaataacagt aatggccatt 2059621 tcctatatac actaacatca cctccgggta gataagttaa ccttacaatt ttgaaaattg 2059681 aaaatccata ttaaattgct ccgttctcgt attcatcatc tggatcattt ttatcaacaa 2059741 taatgatctt ctcgccaatc tccgttttac gatcgacctc tacgtattcg cgcttgatgc 2059801 tgctaagtgt ttcgtcagcc agtacgtgaa tcattacagt tgagttcgct ttaatttccg 2059861 tcatttactg caccctttat atttttttta tgttttttca attcttttta gattttcata 2059921 ttggatttca ctcttttaat tatagaggcg tgtcatacac atgccatcta agagagatag 2059981 gacaattttg tcttggaggt gaaagctaat gaattttctt cttgatcttt ttacaaattg 2060041 gacttttgat aaagtcctgg attatacact agctgctgta atttggtctg tatttaaatc 2060101 cagatcaaag cagaataagt atccaggcta tttcgagaaa atacgccgct atagaaattt 2060161 acatcccctt ctgcgatcgt tatcgatgcg tgtactttta tcgataacga tccatcctta 2060221 tatgtttagt taaaaactat cttttattta gacttaatgg gataaaatct tcattgtaaa 2060281 actcttccca ctcagcaatt aagtttctat aatagttttg gttagagtcg gttggcatag 2060341 attcaatatt gtcaaaacca ttaataccga catctaattc tactgtcact aatccttggt 2060401 aaaacttctt ataattcttt ttaattactt tgaaaaattc aacatcaaag aagtcttcat 2060461 attcagttgc tccactccaa gaatcataag aggacttaac acgataatta aaaagaacca 2060521 aaactaactc atctttcaca tcttttgata tttgctccat taattgattt agtccttcac 2060581 tggcattaaa atctacaatg cttaatcgga agtcaatcca agtaacagct tcatctttta 2060641 accttccttc tccgtcttca ttcacttcaa ttaatacata tctgtcagcc ataattccct 2060701 cctaatttat ttgtttaaaa tcacgatttt aactatttat gatccattag tcacttccaa 2060761 agcaacttcc atttaactca taattaatat ataaaatgta aatggagttg atatatttga 2060821 accttcgaaa aattttattg agttctgctt tatcattagg tatgctggta tctgctgctc 2060881 ctgtcttggc aacaagttct tcgtctgaag tgatagtaaa aagtgatgaa tatgattatg 2060941 acaccatata tcagcttagc cccctaccaa acttcaagcc ttctattgaa tacaatggat 2061001 atacttatac tctcacacgt tattatttcg attactcaat tcagttttat acggctattt 2061061 atacaaaagt tgtttaaact tatagggagc ttttttagct cctttttcac ctttttaagc 2061121 aagatatttc tttctatgcg gtcttttatg tatgaaatca aatgctttcc ctaattcctt 2061181 ctcttctgtt accgctgagt ccatatctta tattgcatct aaggtttagt cagtcgagat 2061241 cattgaatat atagtacttt actcagaaca ttttgcttat taaggacata ataagtgttc 2061301 gtattaattt ttcctgttac gataacgatc aaaaacaaaa taatttatct cattttaaga 2061361 cagaagttat tctgcttttt caaaaaaata ttcttgattt tccctttttt agatgcatcc 2061421 ataaagcatt cgatcataac cattatatgt aactgaaatg caggtataag agttattata 2061481 tagggattac actaccatta tctgggggtg tattaacatc caaatactca aaagcaagaa 2061541 caaatgtacc catagcactt ccatttccac accctatcca aattttcatt ttcctaattc 2061601 cacatcaaaa tcaccctttt tcacatcgta atcactatcg taaaagccta tagtatcaac 2061661 gtttttcctt cttaaaattt tcttttttta taaatatctt cccaaaacaa ccactttccc 2061721 ctactcccgc ttatgtttta cgatcgttta ccccctattt actaattaaa gtatcaaaaa 2061781 ttcttatgtt tactgtcttt ttagctcatt ataaattttt acgataagca attgcctttg 2061841 cttttggata tgacttgact gtatttggtg acgatttaac agagaaattt aatgctcttc 2061901 tgactttttt aactgcattg ggcattattg ttgatccaac aactcaaggt atttctgata 2061961 gtgaacaagc aatggattat gattcaccga gataaacccc atacccttct cttgattgag 2062021 gagggtattt ttttcgtttt ttcaaatgaa aaaattgcag aaaactttac atccttttac 2062081 aattttttca atgactatgt tatgattgtt ttcgagagat ttttgaaatt ttcagaaaga 2062141 ggggtttaaa tgagtaagat cgcttctgaa gttgtcgcta ctacactgaa tgactggtac 2062201 attgctataa aaaaacaaaa ggttgatgaa tcaataaaat attattcaga gataaagaaa 2062261 ctttttgatg aaatggaaga agatcaagaa gttcttgcgt attatagtct attagaagaa 2062321 agacataaaa tgttgctgca ttcttcacga ggagagcctt tacaaaagca cacctatttt 2062381 actgaagaca atcaaaactt cataacaaaa acaaatgata aattagaata caacttttat 2062441 ttatttgaag caatgtacga ggcatacaac aaaaactatg atcgagcaat taacctatat 2062501 ggattagctg agaaaaagct tgcagaaatt ccagatgaaa ttgaagcagc tgaattttac 2062561 tctaaagtct cttacttata tactcttgtt aaacaaagca ttgtggcaca acattatata 2062621 aaaaatgcaa tttcaatata taagcgacac cctgattata aatgcaaact agctacatca 2062681 acaatgattg cagctgcaaa ctatgctgat atgaaacgat ttgaggaagc agaacaatat 2062741 tacttagaag caattgatat tgcaaaagaa acaaaagatg aatttttaaa agctcaatta 2062801 tttcacaatc ttagtatcgt ttattctgat tggaacaaac ctgataaatg cattgaatct 2062861 cttgaaaaag caataggaaa tgaatcttgg ttacattcga tttattatat aaattcttta 2062921 ttcatgatga ttaaagaact ctttaaaatt gacgaaaaaa tgaaagccat taatttttac 2062981 aataaagcac aggaaagact catattaatg gagaataaag tatacgaagc caaaatcagc 2063041 atcctgtata acctttattg tggggaatta aaaaataatt tcaataattg tattagtaat 2063101 attgagtttt taaaacagca aaatgaactt gaaagtgtag atgaattgtc ctacatagct 2063161 gcaaaaaggt ttgaatcaat aggtgctttt gaagaagcaa cgagcttttt caatgcgaaa 2063221 atttgggctg aacagaaaat gaatcaggtg gagggaatct tatgaaaaaa cttgtgcttt 2063281 gcgtatctat tttagctgtg attttaagtg gagtagcttt aacgcaattg agtacagatt 2063341 caccatctaa catccaggta gctgaaaggc cagtcggagg ttaaaaaagg ttgattaatt 2063401 aatttagccc tactcaaaca tttgagtggg cttttatttt atgatttatg tccaccggtc 2063461 agccctgctc tgtggagcgc agtacctgca aacgtaactg agatacttct cactgttttt 2063521 tgcccgagta aaacttatta aagaacatca agcaacactt ataaatatcc atcgtgatat 2063581 ttgtgggaaa atcaattgtt ttggatcgat gaaaaccacc gccaagctca tctttactgt 2063641 atccaattcc tagacttatt gttcgaccaa ctttattata tgtacgtgcc cttcttgcga 2063701 cttcctcaca aatctccaag agcacagctt taatctcttc tctctttgta taatccctaa 2063761 acaaaatctg actcttacca aaactaatct gcccctgcat caatggagct cctatttcag 2063821 ataaatcaat tccgtgagca tgatagtaca actggtttcc cattattccg aacttctttt 2063881 caagcagctc taaaggaaat ttagctaact gacctacagt tgatataccc attcgattca 2063941 gatttctttc catcctccct cctatccccc acattttaga caaaggtcga actttccaga 2064001 gtctatttgg cacatcttca tatctccaac gtgcaatacc actctttgtt ttcttactct 2064061 ccaggtcaag tgcaagctta ctaagcaaca tattgtcacc aattccaact gtgcacatca 2064121 aaccaaattc tctccacatg ctgctttgga ttgctttggc catttcttca ggattctctt 2064181 ttcctgcatc taaaaaagat taatcaattg aatacgtgtg gacacatttt tcaggaacaa 2064241 atctgtaaaa cagctttgta atctcagttg aaactctgat gaaaagcttc atttgtggat 2064301 ttacaatgta tattcttgga tcttcaggta tctcaaatag tctcgatcct gttttgattc 2064361 caaaatcttt tttaagtgca ggagatgcag ctaacactac acttccctgt ctatccgtat 2064421 tccctacaac ggcaagataa catgttaaag gattaagccc cattgctaca gccgatacag 2064481 aagcataaaa ggatttcata tcgacacaga gtatattctc acgtggaaat tgtgagtaat 2064541 cagtcattgt atataactct tatgatgtta ttcatgttga tataaactgt attgtcgttc 2064601 tggtctttta cgtgaagctt ttgttgttca aaattaatgt aatgtactct gccggtaaca 2064661 ttttcaacaa atcccttgtt aaagagtttg aatttcaact ctttattaaa ttccaatgcc 2064721 tcagaaacga gaatatccat ctcatcaatt tgtttgtcat ctaaagatgg cttttcaact 2064781 tttgatccat caatcaaatc ttgtttaagc tgtattaatt gttctagcat cattgatgtc 2064841 cattgatagt tcctcgatcc ctaaacatat cgactcactc cttgattgat ctaatatcaa 2064901 cagaacaaac gttccttatt caatatagat cagaacaaaa gttcgatgta aatgttggta 2064961 ataaaatata aaggtcaata atgatatccg tagtattaat aaaggagaga ttcttttcga 2065021 cgagggagag tgtgatggtg aatgaagaag aggttaattg gatttttggt cttagttcct 2065081 gctttgatta tgtggggtat aactttaatc gaatcaaaca aaaagacccc tgtagaagtt 2065141 ttagaaagtg cttgggatga atttgggtta tttagttttg aaattggaat aacagatccg 2065201 gcaattacaa taggcatgga tcaaaccaaa agtgaagcaa aactccgtga atatttaaaa 2065261 gataatctgt ctagagaagc caaggaaaaa tataagattt atatattcaa ggatgatact 2065321 gataagctgg agaaagagca tcaagaatat ttgaaagaaa ataatctcaa taagtaaaac 2065381 gcccagcaat taaaactgga cgttaaaaaa cattagttat tctttatttt tttttagtat 2065441 tcacacgtaa tctctctcta tcttctttaa aagaggatat gtagttttta gactctaatg 2065501 cagtcaccaa cgctttatta gttctattat ttgagatctt tattcgtctg cctttttcag 2065561 caatttcaga gtaaggttcc cctattttag ttaaaaattc agtaattgat tcattatcaa 2065621 tatgctttat ttgtccagct agcaacgata acctagtatc caatgttgta ggtgattcaa 2065681 gcaaaaaggt tagtagttca ttggtgattt tcaggttatg ctcattaata aaataaattg 2065741 tatctttaag aatatcatta tttccatctg tcaaacagtt agaatttaaa tgttgtacaa 2065801 atatttcttt gttaaattga gagagctcgt tgctatctat gagttgcttt atatcattgg 2065861 catcaaggga aaaatcacct tgtttatcaa taaactcgtc agggtttctc aaagcgagtt 2065921 ggatatgaag tgtatcaaaa tttaatttta actctttaaa attttccggt gttagagata 2065981 acaaatcatt atcaatcaat aattttgctc ttttttcact aacatttccg agcggaaagt 2066041 aaatccaact ttgaatacta gcaattaaca cttcgaatgt ttcgtctgta atatcccgac 2066101 tattaatgat ttcttctgag atatcttcta aaatcgcttc gtcaaattta tcatcaaacg 2066161 cctctatatt atttttagag agctcttttc tattaacagg attgtttaag aaagctatta 2066221 agaaatcagg cattttttta ttgtattcta cataagaagt aataacgttt gaccagcatg 2066281 caaccatttt attttcacgg atcacaattg gccataactc tttaatcaat tcaccaatat 2066341 ccgagatggc aaaagttttt ttcatgatca ttgcatgctt tactctctta tctaaatcct 2066401 cccgatttaa taactccaga aaactttcct ctggttcctc aatctcctca gtaagtaaaa 2066461 ctttttcaac aaatatatca atattgtcat ttacgtaatt gataacagcc tgctgatcag 2066521 agtttttaac tgcagcatac gttatattgg gagcatcatt taaaataact gataaagttt 2066581 tgatattaat ttcgtataga tttcgttgaa caacaaagtc atatattgtt tcagaattta 2066641 gcaaatgatc caaactttta aatttaactt ggagttttaa tagtagttct tttattttct 2066701 cctcatcaga tactaagctg agaagattta agtacttgga taatgtgaaa gacatgaccg 2066761 actctttatt cattcggata atatcagcta tatcagcata tgtaagtata tctgacaagt 2066821 attcctcttt tttctgttgt gtataattgg atctaagttc aataaaactc caaaaatcat 2066881 cccatttact agatatcgat tggataaagg cagctttatt tattgccctt tctttaaaac 2066941 catctatgaa tgtaacagat tctttacttc catttgcaag tcgctcaatt atgctatcat 2067001 aataattacg gtattcagaa tgatccatta tatagtttaa gagatgaaaa ttaagtacct 2067061 ctatttgctt aaattcagca ccaactaatt tgctcattat tttaccgata ttatccagct 2067121 caaagctgta aggcaatgac tcgtggtttt taatactaaa tacaaattta atatcggaaa 2067181 gacttaaact ttctggatag aagtaagtga tgtaatggtt atacatttca tcaatatatc 2067241 catgacgtag caggtaaaca agtaattttt tctcgtaaag cttatcagaa aatacatcct 2067301 ttgaattcat ttttgtaatt aatacttgta aagattgcgc tcttatttct tgcttttctc 2067361 tctctaattc caatagttct ttcttgaatt tttggatttc atttttctct atagccttga 2067421 tggcatcttc tctttcaaag tagttcggtt tccgaccaaa aacagttgca atttctttaa 2067481 ttgtcgctgg accatttcta tttcttaaat aacaatagat agtatccgca ttttttaact 2067541 tctcaaaaaa ccgatcttta ttagatgtat tgcctctaaa tacctcgcca tctatattaa 2067601 tatcataatt agaattcaaa tttgatattt ctaattcgct caagtatata aaatttaatt 2067661 cagcaattga ttttaaagac tcaacttcta tattcgctaa tttcctctct aattgttgta 2067721 ttttagcatt aattaatttt atttgttcct caattataag ttgttttttt tgaaagattt 2067781 catataccaa ccctttgtta tattgtaatt tagaaaaatc cacaggataa atatttttgt 2067841 agattatcat tgctaacatt ttgttaggat caagatcaat tgcacttagt ttttgttggt 2067901 atataacaaa ttcattaaaa atattcttta atactctcat gtcatcaatg taaattgtta 2067961 catcctctaa gaaatgagtg tttatcaaat cagaatatgg tgaatgtttt attttctttt 2068021 taagtatgtc tcctgaatta gatgcattaa taattggtat tactgggata ataaaatcaa 2068081 aaaattttgt gcggtctcta gttaactttt cagtgtctgc atctccaaaa atatcatctt 2068141 ttatcgcata tataaaaaca acacgtctat ctatttgttc tgaattattt ataagttcat 2068201 ttaattctct taatctttca aaaataccta tattattaaa gcgatctaag tcctcaaata 2068261 ttacaacatt atacttggag gcttcaaaaa aatataatat ttcatctaaa tatttatcaa 2068321 atatagaaga gttttcttcc cctgtatttt tttctaacgt tgtattagca attgtaacct 2068381 tattcaattt taagttggca cggacaaaat gataaattct tttatatgcg agtagaggat 2068441 atactataaa gaacagtgct aataatatag tcagtcgtat ttgttgctga tcttcagtac 2068501 cgagactcct tgaaactaac gtctcagcat atattccttt aagtgcatca ggtttaaaaa 2068561 ggtagatgcc aactataata aatgcaaaaa agaaaatcaa atttataatt atgctcttag 2068621 tccttatatg cttaattctt ttaaacctag aaaagggaat ggttctatcg tgtacccggt 2068681 atatcatttg ttgcaagatg cttttctcta acttattctc catatcatcc gtatctgtgt 2068741 tgaatgtagc taaggatata tttaagaaac tatattccct gctgtattgt ttttgaaagg 2068801 tatttaatat gctacttttt ccagacccgt agggaccagt tagggcgata tttttcactt 2068861 ttttattttc taacccccaa cttagtgctt tagaatattt tccatcagtg tcgacatcat 2068921 tgctaggaga aagatcttca aaaaggcttt cttccttaac attaggttct tttagtctaa 2068981 tcagaagttt ctctaaccac tgcacaaatt tttttttgat ttcccccaaa aaaaacaaat 2069041 cctttctaaa ctttcaggtg taatacgaat taataaaact ggagcaaaga actaaataaa 2069101 tgagtatgta gcaatgacaa atcatttctc ttccatctaa tatagtcctt tatcgccagt 2069161 tgaaattcac tattaattgt aacatgaaag ggcattaaaa gtttctgaaa aaaagatgat 2069221 caataaacaa cacagcgccc aattacagga ctgtttcata tttaaattga atttttataa 2069281 gcattaattg cttcatttcg cagcagcata ttatctttgt taaccatgcc taagttgtaa 2069341 gcttttttga taatatctaa tacctgagaa tctaacgccg aaagattacc gcctggatta 2069401 aatcttgatt tccaataatc taaagaatta tttaggtcaa gtgagctttt tttgttctcg 2069461 ggtttaacta cttcattttt ctcaagtgtt tcacagaatt cactaaaacc aatggatcta 2069521 ctgggagctg agttatttcc cccgtatcct tctgtagcca agctgcaaaa tgctaagaat 2069581 tttggatcat aaataagatc gcttcagttt acatttacca ctgataatca caatcctctc 2069641 aaagcttttt ataattgtag caccttttcc atttttacac atattaaata tcgacaatca 2069701 ttcaaatgat ttaataattg aatacaaaaa agaacctgca ttttgcaagt tcctttcacg 2069761 ttgtcaatat attgtgaatt tttaacgaca agggcattta tgtatagtat gatatttcct 2069821 gtacagtaag ttttgctcac tcgagggagt cttgctcatc ccctaatgaa aggggtgatg 2069881 ctatgtcaac attccaggca ttaatgctaa tgcttgcaat cgggtcgttt ataatcgccc 2069941 tattgacgta tatagaaaaa atagacctcc cttgagcctc agaacctgaa gggataggcc 2070001 tacctagaac cacatcgagc aagccctttg atgggcaact ttttgtacag agccggggtg 2070061 ttggtagcac ctcggtcttt tttattttat gcatttctca ttaaagaaat gcactgtaat 2070121 gtattgtaaa actgattata acacattttc cgtgaaatgc attacaataa acctcaagag 2070181 acttggaaag cttttttatt gtttcttgta acgttataat gatctaaaat agcgcacaag 2070241 cctttataca tcttcatcat ttcttactct tctagctcgt ctttcaacat tccaattccc 2070301 aatctttccc cagacattct tgttagtcca tttccctagc ttagttttat caaaccattc 2070361 ctgaaacaaa gatatttcat ctttcctttg cattgtatct tttaaaagga aataatgtat 2070421 tatccaaaag atataaagag ctgaacaaga aagtccaaaa ataagtttat ttacctctaa 2070481 ccaatttcct aaaacttgtt cgcctaaata tttatcatat agaaggggta taaaagcaaa 2070541 tgctgaagca ccgacaaaaa aagctagagt ttctttaaac catctaacaa aaacaaaaac 2070601 agcgcttaaa atataattcg ttctaaaaag aactttatac caattataat tcttgtttag 2070661 agtaacaaat atacttctat attctttatt aactgcttga tctaacattc tcattttata 2070721 aaataatttt ttcctattct cgctgttctt gtttaaaata tactctctga aacaatcttc 2070781 tgtattcaaa atttgatcta tcaataagat gtttctaagt tttgatagct tccccttttt 2070841 cccactatat tcttcgaaaa atttttctat aaggaccatt ttatggtttt catcttcttc 2070901 attctttatt tcttttaggg aataatacat aggctctaaa attttttcta atgtttcacc 2070961 tgattgagag tagaatcgtt ctatactttt ttgtctttga ttgaatagca atgcaactat 2071021 acccgtaatt actgcagtaa gaataccatt ttgttgtatc caattccaaa tatctaataa 2071081 ctccaattaa gcttctcccc ttctctctga atttactttt aatacgggct aaaataaaaa 2071141 aggtttcata taaaacggga ctagaaaact tctgtcactt taattattta atccaataaa 2071201 ataagctctc attgcgagag cttattttat ttagattgag gatgtgcaac tcaagccttc 2071261 tattgcgcta tagcaatact tttgcttaat cgtcccagtc ttcatcctca tcccagtcat 2071321 ctttcgcttc ctgaatctta ttataaaaaa attcaataaa gctgtctgca acagtatctt 2071381 gataaccaat taccctatcc cattcaacta cagggcattc tccgtctttc attttatttg 2071441 tatctagaca gtaagcaaag taatcaacat cttcaataac cacaagtcca tcagtaaggc 2071501 catagtgttc tttatattca ttagttctat ttacaactga tgcatgatca aagttgtagc 2071561 ctaaaaccaa aacgccgaat aaaccaccag caccgtattt ttctaaaaac catttataac 2071621 tgttggggag atcgcattgg aggttttctt caatgcgacc aatgttttca tgacttgcac 2071681 cttctgtaaa tatagcattt tgtttatttt cattaataaa gttctcaacc ttcgaataaa 2071741 tcatataaac acctcaattc tcattttcaa attgtttcgc tctccatttc caatatctct 2071801 ttctaaagct ctcgtattgt gcttttaaaa ccttatcatt tctaaaactt tcaccatcag 2071861 acttaagctg atgaatgaca tcactatatt ttgtatgtaa gctgttcggg atttcaagca 2071921 ttgggccagg ttcttcttga atcaagtgat gtaaattaat ctgtgtaccg tcttttgcat 2071981 aaggggcatt cccgtttttc attagctgaa gatttgtaac accgaattct gttttttgat 2072041 taatatcaat atctttcata gtatacactc tacggcttac atctttaact ttccccttcg 2072101 cctttacctt cccctctatt tcatatgcat catacttttc tttatttagc caaggagggc 2072161 ttttcttttg gccagtaaac ggttttcttg ttccatccgg tattttcttc gcattagtca 2072221 aaagttcatt cttaaggttt tggctatcaa ccacattgta tggcacgtta tctgctagag 2072281 caagcttata cttagggttg taaggcagca aatctggaat cttaacgtcc ttgattttct 2072341 tacctgcttg acttgcttta tttattacct tgcccgctgc atctgctttg ttaatggctc 2072401 ctgcaccttt tgtaccaaca acagctacag ccactgaacc aatagcatag gtaacccatc 2072461 ttgatctaga ataggcatct ccattcacca tatccttttg atatgactct tctattgctg 2072521 ctgaaatggc atcgtatgtt ttcactggat gcatagctgc attacccagt gctgagagtg 2072581 tttctcctgg atcggtgatg aagtcccata tgccggttac agtgtctttt cctacatcgt 2072641 ataaaccaac tcctacacct tttacgatat cccaggtgat ttctcctgct ccttctagct 2072701 gcttcgcttg ttcaatttgc actgcaagct gcacttgagt tggctccaga ttctcgtacc 2072761 ctactttctt agcaatctct aaatattcat cagggtcaga tacaccgtca ttaagttttt 2072821 tctttaattc cttgatttca cgttcctttg cttcttcttt cttcacactt aagtaagctt 2072881 cagaatgctt ttcaatatcg ccttttttct tatgtatgtc actttctctg tacgctttag 2072941 cgttatagtg aattggtgta gcgttttttc ctttgcctgt tgattcctgc agctttttaa 2073001 agtcttgctg aataaattgt tcgtttggtt ctgtttcagc gtattctgtt tttaaatcct 2073061 catcaagctt gtttagctta tcgattgttt tttcacgttt gtcatctgca gaagaaagtt 2073121 tgtctttgaa gtcttctgtt gagaatattt caaggggaag gatatcattg atgttgttta 2073181 atatgtcttt cattgctttt ttctgttcag acataatgga ttttgatttt gcataagcgt 2073241 tagccaactc gtgttctaga aaggattctt ctatgtaagc atcagacatc ttcgcatctt 2073301 caagtgttgc agacatgctg cttaagaaag caatcttcat atcgataaga tcaatccatt 2073361 ggtctgttac gccgacatga ccatgataaa atgctttaat gttgtcagca cccttgcctg 2073421 aaaattcact gtcatctagg ttagctactt ccttaaacgc ttttttgagc ttcaccattt 2073481 gcgaccttag ttccttatac tctttggttc ttttatccgc ttcaaagagt aatgaatcag 2073541 cctcaaatac cttcatatca ttctccttcc tagactactt ctatgtaaat tttaccacag 2073601 taatctaatt gaataacaga aaaagacagc caaaatgact gtcttataca tcacacacta 2073661 tcttgttcta taataatttt ctgcggtata gtagcgccaa tcccaaaaag gttccccatt 2073721 ggccaatata taccggtcta aaaatttttc aaagtttaaa tttaatggat tatattctaa 2073781 accactttca aatatataga gatagttggg atcaccttgg ttcactttat ctttatcgat 2073841 cattaaatgg cattcttcca ataagtagcc aattggaata ccattgatat cttcaaacaa 2073901 atcttcatat tttaactcct cttcaatctc ttcaaggcta aatagctgaa gtcctccacc 2073961 tatattctcc ccatcagaaa gaatctcaaa aattttcgca ccgttatgta gtgtcatgaa 2074021 cttctgataa tcctgtggaa gggtaagctg gtgtttagcc tcaaagcttt gaatgtcatt 2074081 cagggttgct ttgtcctgtg aaaaagtaac aaggaactcc atgatatcac cttctgaaca 2074141 aaacaattta atggctcctt tttcgtctaa aagacttttc aagccattta cagtcttatg 2074201 aacaaagtta gtcacataca tcaccccttt atttcctttt aacaataacc tttcaaattc 2074261 caaaagatgt gaacagatcg tgataggtgc tcttttcagt gaatataatg caataaattc 2074321 taaaaagagg tgcctccaaa aattgaattc tctaatgaat gatgacatgg taaagatcat 2074381 tagaaatggc cttagcgcat cgcagcatcc aaagcacatt cttgttatag gagctggatt 2074441 gtccgggctt gtatcagcat ctttgttgaa aaatgccggt cacagagtaa cgattctcga 2074501 agcgagcggc agagcgggcg gccgtgtctg cactttgaga tctcccttta gtgatgattt 2074561 gtatttcaac gctggcccga tgcgcatacc gaataaccat tcgttaacct tagaatatat 2074621 caaaaaattc aaattgccaa caaatgtatt tatcaacaga accccgatgg acatcattta 2074681 tgcaaatgga atcaaaacac gtctccaagt ttttgaacga gctcctggaa tattgagata 2074741 tccagttgca ccaaatgaac aagggaaaac gtctgaagag ctgatgcttt ctttactgca 2074801 gcctattcta aattttatca atcaaaatcc agcaagaaat tggcggattg tcgaagaaca 2074861 atacaaaaat cattcgttaa gctctttttt aaacacgtat ttttcatatg gcgcgatcga 2074921 tatgatcggt gtacttttgg atatggaagc gtatatgggg atgtcccttg ttgaagtatt 2074981 gcgggaatct atcttttttt catcccccgc tcacttctat gagataactg gcggtatgga 2075041 tctgctgcct cacgcgtttc ttcctcaatt aaaaacaaac attctatacc atcaaaaaat 2075101 gatgaaaatg tctcagggtg aaaatcgtgt tacgatccat tgtcagcatc aacaaacggc 2075161 agaattcaca tcattcacag ctgatctcgc tattgtaacc attccttttt caacattgcg 2075221 atttgtaaaa gtcgaaccat accattcatt ctcttactat aaacggaggg ccatccgtga 2075281 gctaaactat atcagtgcaa caaaaatcgg catagagttt aaaagccgat tttgggaaaa 2075341 agccggtcag cacggcggca aatctattac tgatcttccg attcgttttt catattatcc 2075401 aagcagaaat attggagcaa atggacatgc tgtcattctg gccagctata catgggccga 2075461 tgaggcactg atatgggaca gtctttcaga aggagagcga atccagtata ctttactgaa 2075521 tttatctgaa atctatggtg atattgtgtg gtctgaattt gtgtctggca cttcttttag 2075581 ctggagccag tacccgtatt ctgcgggagg ttttacagct ttcgaaccag gacaagaatt 2075641 agagctgtat ccctatattc ctgtccctga gggcagagtt catttcgccg gagaacacgc 2075701 ctcactcact catgcgtgga tgcaaggcgc gattgaatct ggaatacgtg ttgcttatga 2075761 ggtcaatcgc ttaccttaga tcatgctcac atcttgttaa aactggttga tataaaaaga 2075821 agtgaagaat ttatactcct ttgtttaaaa gattaattca aatatgggat gtctcaacat 2075881 tcggttcttt attatcttta tacacgtttt gaatgcggac ctcccttttc ttccataatc 2075941 attaataaat acccaaccat aggaaacgtt ttaattaacc atcgggcgaa ctttctttca 2076001 ctgtataacg attcttaatg ttgcttttta tcctttactt gtcctctctt tttttcattg 2076061 acttacattt cttgaaaacc agtataaatc ctaaaggaat tttgtaacaa atacagaatt 2076121 ggaaagagaa gcgccaaaag aaatgctaac tccttatctc aaagacaaaa ctgcgcttat 2076181 attaaaagaa agaggtgtct ttagaatggt tcattttaaa aactgccctg atccttctct 2076241 aaacgccaat tctcagtctc accccgaatt ttcatccgaa ttagaacata ttaagacaag 2076301 aatgcaaaac tttattaagc actcggttac agaccaaaat atcgaagtta ctgacgcaag 2076361 ggtgacggcc gaaggagagg tcacctctct tttaaaagaa cgtctcgaca aggaatatta 2076421 taggctttta tctaaaatca cccgggaagt aaatgtggct gacttcggcg ctgttccaga 2076481 tggaagagac aatactgaag cttttcgaaa agcaatcggg aatggccgag tcaaagtaca 2076541 tgttccagcg ggagaatacc tcgttcaagg gattaaactt ccatcttgga caacaattgt 2076601 tggacaaggt aaagggatca cagtgattaa attgcatgaa gacactccag cgcatgaatg 2076661 ggtgattaca aatgatgatt atcaaaatgg aaatcgcaat atttttgtcc aaggaatgtc 2076721 attagactgg aatccaagta gacaatgcgg tgtgagaaat ccagggggac agttctccag 2076781 ttgtttaact tttgctaagg ttgaatatgg gtggatcaaa gatgtggaag cgattaacgc 2076841 aggtcttcat ggtattgata ttacatcgcc aacgtatgac catttgcctg ataccgattg 2076901 gacaaaagac ggatcaagat atatttggat cgataactgt gtgacatatg gttcaggaga 2076961 cgacggcatt accacccatt atagcgaata catctttatt tcaaactgcc attcaggaaa 2077021 tccgcgggga acagaatttg ctgaaggtgt ttcaaactcc aacggaatag aaattgacga 2077081 cggctctagg catgtgtggc ttttgaataa ctttacaagc ggcaacatcc gcggagttga 2077141 agtaaaagcc catgaactgt ggccagcctc tcaaaacgtc catatcatag gccatatttc 2077201 ttatcgcgat gttcgtgcat ttgatcttcg tcatattggt caccatcaaa ttacagatcc 2077261 tgaaagcaca acagcatacg atgtcacact cattgattgt tcagcagttg aaccagtttt 2077321 caactcgctt tacgatgctg tgaccccaag agcgctggtt atttcggcat ataaaaacgt 2077381 taatgtaagc ggattcacag cgattggtga tccagactat gattataaag aaaaccctgt 2077441 cgtagccttg caatatcgca gccaaaatat aaccattaat ggtattaaaa ttcgcggttt 2077501 taaaaaagcc ggtgttgata ttaatttatc aggcggatca aataaaactg attatattaa 2077561 aatttcaaat tttgatattt ataaatctgc tccaaaagga atttcaatcg gtggaggcct 2077621 ctacaatgtc aatattctaa atggaacgat gattactgac aatgggacag ttgcaattca 2077681 gtcccccaat aatcaggcca caattctcgg tgtacaatca gaaggttata gtgtggcagc 2077741 ctcaatcaaa ggccaaacat accaacaagt tccaatcaat ttgaaaggag gcatacagct 2077801 tgcaacgacc tctggctttg ccgttaacca aacaagcgca gttatagcag gtaccggcga 2077861 cattacggcc cgcggagaaa gaaatgcggt cattagctct tctggaggct ccagtactga 2077921 aggctctcgc gcattaatcg cttcttcaaa taacgcacat attagaggaa accaagcgtc 2077981 aagaacaata ctgtcttctg aaaatattat acttgaggaa ccatacaccg tggcaggagg 2078041 tcatcaatca ataaagtggc ttcttgactc tgttcgggga aacgggacgt ttgccggtgc 2078101 aatcagttct tctttaggtg gatatggaga gtattttgag agttcaactg gacagttaat 2078161 ccatactggt acaatcgtga ctttaagagg tgaaaaaatt gtgcccgcga atgttggaga 2078221 ttatatgctt ggcgttattt cagaaacttc agctttcatt tcaggagcct ccagtttcgt 2078281 ctggcagggc cgttatttga caaatgagtt cggcggattt atttatgaaa cggtgactga 2078341 tgaggaaagc ggtgaactca tacgtgttcc caaacaaaat ccagactacg atacagcgct 2078401 ggaggcaaat tatcattcac gggcagcaag agacgaatgg cacgttgtag ggttggttgg 2078461 ccaacattat gtgcgtattg acgaaactgt caatcaagga gattatctta cggcacataa 2078521 tggaatagga acaaaagcca ctgaaggaag ctggaaagta atgaaaataa cctctgctta 2078581 cacatcagaa aaagggtatg gtatcgctct aaccgtcatc aaatagtgga tacgccgacc 2078641 agttcaatat atgtttatcc aaataattag atctcttttc taggttcttt attccttgta 2078701 tgttattatc aattttcaat atctaccaaa atacccctaa tatactatcg taattaactt 2078761 atattataat caaaaaaatt ttgacagctg ttccttctcg ttattcatga aagttgctat 2078821 tgaaatgagt aaatggatat catattagac ttctatagca aatacaccat atatatcctt 2078881 taagtattta caaattgaaa atgtttcatg aggcttatta aaagtattgt tcttttatca 2078941 tctgtaagtc gatacaaact gcattaagat cacacctaaa tctcactgag ttttttctta 2079001 caaataaaat gaaaaccctt tccattctaa attcatttca ccgttactaa aagtaatcct 2079061 tgcattcctt cgccctccat gctatattca tatagcgatg agctgaattg tgtaagccga 2079121 tgtacatgcc tttacggcac acacgaatgt ggcgtgtggt gcatcgcctc aatacgcaaa 2079181 gacgtttgcc ttaggcaaac gtcttttttt gcgttatccg atttttgtgc cgtttgggac 2079241 aggctgatcc ggctgcaaaa ggacgacgtc gccctggccg ggtatgccgc cgaggaccaa 2079301 gacttccgat ttaaatccgg cgatccggcg gggcggaaag ttcacgactg ctatgacttg 2079361 cttgttgatg agaccttccg gcttgtaacg cttcgtgatt tgtgcgctcg attgttttat 2079421 gccgatttca gtcccaaaat ctatcacaag cttgattgcc ggtactcttg cttcaggaaa 2079481 ttcttccgct tttacaattg ttcccgttct gatatccaat ttctcaaagt catcaataac 2079541 tgccatatca ataactcctt tttctcctat tgtaaaggag atatacaata ttcttttaac 2079601 taaagagcca tcatttttta tccgaatata aggtgtttcg atacaggcgg ggcggcattc 2079661 ctgtgctttt cgtgaaccat cttgtaaaag aagaaaggtt ttgaaagccc agcgcctcgc 2079721 tcacgacggt aagagtttca tttctctcca tcagcattct ttttgcttcc tcaaggcgaa 2079781 ggtcggcaat atagttctgc ggggacttcc ctgtctgttt tttgaaccag cttgaatagt 2079841 aagctgggtg ataatgctcg atttctgcca gcttcttaat cgtcagccgc tcaaataaat 2079901 ggctgtgaat gtatgcaatt gaggcatagc tatgggattg aagcttttct tttatgtatt 2079961 gtactagcat atgaagcgag ttggctgttc cggcctttgc ttcctctgtc agcaagtacc 2080021 tgatcgaaga ccagaaagga tcgagggcag cttcaattcc tgatcctgca cgatactcat 2080081 caattttcat tgcatgaagc ggaacatcca gtacaagaca ttcatttctt ccgatagaac 2080141 ggaagcgatg ctcgcactgc ggcggaatat ataaaaaatg atccggattt aatttcacct 2080201 ggcgcccctc agtctcaaga tcaatactcc cttcaagcgg aaaaagaaat tggctgtacg 2080261 cgtgcttatg tgaatgatat agccgtgtgt atgtccgttt ttcgcaaatt atctcttgaa 2080321 gcgagtccat tagcaaaccc cttcctttgg tcatctttta atccggtaat ggtgttccga 2080381 tataggcgaa aagccgattt ttccatataa agaaactgcc gccagatttt ctttcatcac 2080441 ttgtaaaaac atgcgttccg ctccgttgtt ttttgcccat tcagtcaaca ccctgatcac 2080501 ttgggttcct gccccttttc ctctgtgctc ctcagctaca acgatattac taagtccgcc 2080561 ataaccatca atgacagaaa ccgtgccaag cgctgtcagg ctttctttgt catacatctt 2080621 gaaaaaagtt ttacacggcg gcatgcgttc gaatatgtgt ttgtaacctt tgtgacgctc 2080681 gggtgaaaac ccttctaatt gaataaattc atctatccaa acagatgatg gctcttgttc 2080741 ccacttgtat gtaaatcggc tgttgtcatt tgttcggctc ataattgacc ggcacaacgc 2080801 tgtcatctgg aagcactcgt ctaccttttc ataacggctg tctgccaatg cgtcatcaag 2080861 ccctttcggt gatgcgttgc taatatgaaa acaaacaggt aagcctaaac tttgataaaa 2080921 aagttcggcc tctagctgaa aatccccttc aggcatatcc gcagacgtcc atacgctatt 2080981 tgcccttttg gttacgccaa aattcgctct gagaagccat ttccctatgc ttttttgaaa 2081041 ataagccggc catgaagctg ccgctaatcg ttcaatcttg cgaatgtcat ccattgcata 2081101 atgcctctcc cctatgtata ctcccttgat attatacaat attcagaaat ataagacatc 2081161 catttatttg tttacataat atttttattg tttattaata atcctgacaa aaatgtccga 2081221 attgaaaatg acaggctttc taaaatgtcc tcctcacgtt caaatgcttc ttttgcgatt 2081281 aaaacagtaa agccatgcag cagacttctg agcccccttg tcgcatgaat ggcagtcttt 2081341 tcacttgcat agccgttttc aatgagcagc ttcgtcacaa gacagacaat ttggtcagag 2081401 acgatttccg tccgtttgtc gtgaacctta agaagagccg cttcataata tccgggattt 2081461 tcaattgcaa aatcaacata tgcatgagct aaagaaagca tcgcggaatc tccctttcgt 2081521 tcggttacgg agtccgccat ttgatcaaaa agctttgtca gtcctctgac agcaagttct 2081581 gctctgatcg cttgcagccc gttgatatgg ttatacaatg acggggggcg aacattcatt 2081641 tttttagaaa gtgcagcaag tgagacacca tttacccctt cctgatcggc aatctctgct 2081701 gcagcgtcta caatcatttt ttgggtcaaa cctattctcg gtgacatgct catcatcctt 2081761 tctttgcttt ttggatcgcc tgtctcatcc gctctgaagg tgatcgcagg aattttccat 2081821 gtccgacagc gagacaggaa ggcgccttat cggcgagcaa ttgtgcactt ttgatggcct 2081881 cctccttatt ccatgtggcg aaagcgggaa aaggaaacgc ccattttatc tgacctgata 2081941 cagcgattcc tccgcgcaac tgaaacgcat ctcctgctat taaagtgccg tttcttgtat 2082001 caagaaatga catgctgccc ggtgtatggc ccggtgttgg aatggcaagc agagaaccaa 2082061 ttgtttcacc gcccgtcagc agttggtgag gctttgtttg tatgtgtttc ggaatacctc 2082121 cttttatagg cgtctgcggc tcatcttgcc gcaaagatgt gtcaccttgg agcaagaatg 2082181 aatcccgttc cgagatcatg acctttgcat gcggaaatgt ttgtgccaat gtatccagtg 2082241 atccgacatg gtccccatgt gcatgagtca gtaaaatatg ctgaagcggt tttccaagct 2082301 gattcacagc ttgaataatc cctttatagc tgcctggcag tgcggcatca ataagggtga 2082361 cttcgttttc ttcctctact aaatagcaat taaccggaaa caatgctgga aaaaaagtca 2082421 gctgccaaac cgtttggtac tgagtaattc tcatcttttt attcctccta acaaaaacta 2082481 atggtgttag ttttattatt aactaacacc attagttttt caagagttta ttattttttt 2082541 atcgctacat aaatgttaac ttgtgctcgc tgtggcactg cggcattttg atcatacatc 2082601 tcaaagtcac ctgtaaacgt gcgcagatgc cgcttatccc aagtccaaat ttccttccac 2082661 gtttcaagca caatctcttc aataggaccg attctggaag tgaaaacggc gtaagcggaa 2082721 gccggcaaat caatattttc atatggtccc ggaagaatgt cgtcgtattc ctgaaacgtt 2082781 ccgactgaaa acgtataaaa cccattcgtc tcttgttcat aattcgaata taaggcaata 2082841 atgctcttgt ctttttcagc ctgtgataaa agagcgctca tatcctgctt ccataattga 2082901 tcccacagtg ccggaatcct cctttcttcc gtcatttcca gtgcgttgct tgtccgttgt 2082961 gatagtccgg caaatcgttt caggtctaag tgtgttatat gtgaaaagcc catacgatct 2083021 cctccttttt ttaagattat agacaaagaa acctgacagc agtgtgtcag gtttcatata 2083081 ttttttgcat gtgatgaatg gtttctttta ctttatccct tatatgaaga ggctgcagaa 2083141 cctcaatatc ctttccgaac tggagcaaaa aaccgatcag ccattgatct tctggaagtg 2083201 aaatcaccgc ctggcagatt tcatcttcct cacaacagtg aaggacatca tatccgaacc 2083261 attcacctat acgctgacgt gctgacggct gaacaagaat aaccaattca gttaaacggt 2083321 ccttttggta ccaactctta tcccatggca aagtgtccag ctgaatgtct tttctgataa 2083381 atgtctgatg taagatggcc agatctttca tccggttcag tttaaaaaag cgaaaatcat 2083441 ttcttaccag gcagtaggca tataaatacc agtgccccgc cttgcaaacc aatgtataag 2083501 gttcagtttc ccgaagtagt gtttccccgc ttgcgcttgt atatgtaaaa gatatcgtta 2083561 acaaccgatc gatggcagcg ctgattttct cgcgcagcgt cttttgatcc tcagtatggc 2083621 cccaagccgt catgtcaata aaccattttt ctgtttggtg cttaaatgct tgagtagatt 2083681 gctcaggtat aaggtgtttg attttttgat aggctgtgct gtgagaaacg ggttcataca 2083741 tagatgaaac gctttgcaaa gcggaagcaa ttgcaaacaa ttcctcctcc ttcagccact 2083801 ctctttcaag ccgatacgtt tccatgatgc caattccgcc cccggaaccc tgtgaggtca 2083861 caatcggaat accagcccta ttgatcgtct caatatcacg gtaaattgtt ctgacagata 2083921 cttcaaacag ctcagcaagc tctgcagcct gcacttgttt tttgctgatc aataacacaa 2083981 ccatcgctaa caaacgttcc agtttcattc tgcgcacctt ttcttcttgt attttccaac 2084041 aaaacaatca taacattttg ataaagcttg ggcatatcta ttatgcggcg gaatacacct 2084101 cgcatatgct atgaaaacag gggtttcccc ttcttttttg tgttcagtat ttatttcagc 2084161 tactatttcc gaccggataa gcatacactt ctcaacggag gggatttcac atcatgcatc 2084221 ttacacttca gagcgtttat cctgccataa tcatcatctt ttttctgtat aaaaaaatta 2084281 aaaggtccat cggataccag ccgctgaagc cccgctggct gttcacccgt atcattcttt 2084341 tctcgctgtt tgcttttgga ctttcaatct tcagcgccat tcaccctttt ttatatggat 2084401 atctcatttt gggcattctt ggcggatggc tccttgtctt tttcgctaag aaaaacatct 2084461 cttttgaaaa acgcagagga aagatctatt ttcggactca tatttgggta gaggtgattc 2084521 tcttaacttt atttctatca agatttctgt atcgagtgac ggagctttat cttacctcac 2084581 ctgatctaaa ccgccttgga tcatacagtc agtcaatcgg aacggaccct ctgacaattg 2084641 gcgtctgttt tctgatagcc gtttattata tcggtttttc ttcttttatc atcaagctca 2084701 gcagaaacga acttgaacag cacgaataca ataaagaaaa agacatcctt gcccgctaac 2084761 agcgagttaa gcaaggatgt ctttttcaat catgctgtgt atgatggatc atttgctgaa 2084821 gaacatctaa aacatgttca tcctccggag agtaataaat cgatgttcct tctctgcgcg 2084881 atttgacaag ccggagattt tttaaaaatc taagctggtg ggacacagtg gattgcagta 2084941 aattcagctt ttctgcaatt ccgtttactg catgctcacc ttgggacaat aaatggagaa 2085001 ttctgattcg ggtaggatct gaaagcgctt tgaatgtttg cgcgactaga aacagcgtct 2085061 cctcgtccag atcagcagcc gattgttccg tttctctaaa ttcagtcata tgtatcacct 2085121 ttctttattc atagttttat cttataacaa atgcgcttga gtgcaaacca gcctgcttgt 2085181 attccatttc aatctcatag tttaaattta tgtttcaaat caggttttta cttggtctga 2085241 tataccctct tatgtcataa taaaaaaggt catactgctc caaacattga gggtgaaaca 2085301 cagtgaagaa aaagagaaaa ggctgtttcg ctgctgcggg ttttatgatg atttttgtct 2085361 ttgtcatcgc ctctttttta ttggtcctgc tttttttcaa ccgggattta atcaaaaaac 2085421 ttccgatcga tacgaaaacg attgttttgg aacgtttaac cgattacaaa cccttggtgg 2085481 aagaagagct tgaaagccaa ggactctcta attatacatc actcatatta ggcatgatgt 2085541 atcaggagtc aaaaggaaaa ggcaatgatc ccatgcagtc ctctgaatct ctggggttaa 2085601 aacgcaatga gataacagac cctcaactca gtgttaaaca aggcatcaag caatttaccc 2085661 tcatgtacaa gaccggtaag gaaaaaggcg tggatttgga taccattatt caaagctaca 2085721 acatgggggc aggttacatt gattttgtag ctgaacatgg aggaacgcat actgaggaat 2085781 tggcaaaaca atactccgag cagcaagtca aaaaaaatcc tgatctgtat acttgcgggg 2085841 gaaatgcgaa aaatttccgc tatccgtatt gctacggtga ttatacgtat gcagaaaaag 2085901 taaaagaaaa aacaaaaact gttgaagaat ctttgcaggt tgcaacactt gaaaccatgg 2085961 aatccaaggc tcatgaataa gagtctatca atttactgac aaaagcccaa aaatgaattt 2086021 gggcttttgc catgtttaca cgtaaaaaaa gccatactga gtatggcttt taataatacg 2086081 gtgaaatcat caaatataca ataacgcctg taaggcttac atacagccat agaggcattg 2086141 tccatctcgc aattttttta tggcgctcca cctgcatgct gaagcctctg atcagcgtaa 2086201 acagcgcaag cggcacaata attgcagaaa ggcagatatg tgtaattaaa ataaagaaat 2086261 aaatcgggcg cataatacct tctccgccat agagcgtgtt ttccgcaatc gagtggtacg 2086321 tcacatagca aatcaaaaat agtaatgttg ttgtgaacgc agccaaaata aagcgtttgt 2086381 gagctttgat atttttctgt ttaatcataa tcagcgcggc caataagaag ataaacgtaa 2086441 agctattgaa tatcgcattc agcattggca aaatgtgaat attcgcatgg ctgaactgat 2086501 ctaatttagg cataaaaaac agcactgcga ttaaaccgtt aatcagaact gtcagcgtaa 2086561 ggacaatccc cgtgtaattt ttcggtttat tttctgtttg gttcatttgg tgacctctcc 2086621 taatttgtac tggctatcca aatcgtatgc aaattcaaag aagatgtcaa cggtttcgat 2086681 tgcttcgtca gaaattagac acacttcaaa ggccggaggc tattagcccc ggcctgttag 2086741 gtttacgcct cttttatcaa atgttcaatg accttatgtt cattttcatt cagcaggttc 2086801 ttttgaattt tcgaatgaat gggtttattc atatgctgat ccaagatatc ggccgtttct 2086861 ttatccccgg caataaccat tcgttcccat cttttcgcgg cagctttttg atcaaggctg 2086921 gcagccagcc gcttatacag tctcgattgg ttctctgtta catgttccct catccggttc 2086981 tcttcaaatg gtggcgcttt gtctacagcg gaatggctat tcttccaaga ctcattgatc 2087041 atatcatact cataacgctc caccgcctca atttttccta aaacagtttc aataattttc 2087101 acttcatgct gctgagttaa aataaacgcc gtacttgggt atgtctggcg caaacccttt 2087161 agctgatcca ggacagctgt ttcttcccag taaaatcttg tatctacagg gacttgaagc 2087221 ttaataggtt cccatatgcc gctgtcggaa acaaaaaaca cgagactgcg gggcatgtct 2087281 tttcccattg cattcaagta ttgattcatt ttagccctga ttccatccag acacttttcc 2087341 tcctctggat cactagctgc caaatactct tttaatcggc tgaatcctga ctttagggca 2087401 atcttccatt ctcccccctg ctgctctgga tctctcatgt ctgtattgag atacagagag 2087461 agaattttat ccggcggttc caattggaca tactgtaatt tgttaatcaa tgaatcaatc 2087521 gccattccga ttcctccttt ttcacaggtt agttttcttt ttcctctctt aaaaacgatc 2087581 aaacctgact ttccgctaat ttctagtaat aatggaattg ttgtttacaa tacgcctctc 2087641 ttctaataca attggtaact gtgtttctaa gctgtttttt gaaaggagtt tgatcttgtt 2087701 tactgttaaa gaaaaaaatc gtcaagagct tgaggaagaa ctaaatgatt tagaatttca 2087761 aatttatcgc atgcaggaga atatgaagga tttatctaaa gatgccaaag tgcttggtat 2087821 tgatcaatcg aaacatgatg agtggatgat tgtttcctcg attgatgatg gccaaacatg 2087881 caaaattatg ctaactgatt gtaaaacggc ataccgagga aaaggctgtt tttcacttgt 2087941 agcgtcttac aaggacgatg ccattcatat aggggatata aaaggccctc cgaatcacgg 2088001 gtttggctcc atttgcatga aatatttaaa agatattgca agagaccata atataccgaa 2088061 agtcaccgga gacatcgcca aacgggattg gaatcatgta gaccggctga ttcactttta 2088121 tgaaaaacat cacttcaaag tatgtatcga tcatgatacc caatccggca gcattaagtg 2088181 ggttgatttg taaaaaagtc tggaagaaag agccaagata tgctgtaatg gtataaaacc 2088241 attgatggag ggttctatgt acgcctcaaa actgaaaaag ggagacgaaa tccggatcgt 2088301 gtctcccgcg accagcatgt ctatattatc aaatgaagca aaaatccaag caaaaacggc 2088361 gttagaacgc ttaggttatc gggtaaccat cgctgaacac gcaaatgaat gtaacgaatt 2088421 tgattcatcc tctatcgagt caagagtcca tgatctgcac gctgcctttt ttgatccagg 2088481 cgtcaaagcg attttaacga cactcggagg gtttaattca aatcagctgc tgcgttatct 2088541 tgattacgag aaaatcaaac gacatccaaa aattctgtgc ggttattccg atataaccgc 2088601 tctttgcaac gctatttatc aaaaaacggg tcttgttacg tattcaggtc cccacttctc 2088661 aacatttgca atgaaaaaag gactcgatta tacagaggag tattttcttt cttgctgcgc 2088721 ttcagacgat ccgtttgaaa ttcacccctc aagtgagtgg agcgatgatc gctggttttt 2088781 ggatcaagaa aacaggcgtt tttatcctaa taacggccct gttgtaatcc aagaaggtta 2088841 tgcggaaggt actttaattg gcggaaactt atgcacgctt aatttgctgc agggaacgga 2088901 gtattttccc gaaacagaac atactatttt attgattgaa gatgattata tgtcagacat 2088961 ccatatgttt gaccgcgatc tgcaatcact catccacctc cccgcttttt cacatgtaaa 2089021 ggcgattttg atcggcagat ttcagaaagc atcaaacgta tcaatagatc ttgtaaaagc 2089081 catgatcgaa acaaaaaaag aattatccgg catcccgatc atcgcaaata taaatgccgg 2089141 acatacctcg ccaattgcca cgttccctat aggaggaaca tgcaggattg aagctatttc 2089201 gggtacatca cgaatatgga ttgataaaca ttaatcagct tgtaaatttt tttacaagct 2089261 tttttagcgc aatcggctat gcatgccgca cgagacatga caaatgtcat ataggaggca 2089321 tgatgtgtgc tactacaaaa gacttctctc attagcgtat actgaaccga gacacacaat 2089381 gagaggatac ttactatgac tgaacaaacc attgcacata aacaaaaaca gctgacaaag 2089441 caagtcgctg catttgctca gcctgaaaca aaaaacagcc tgattcagct tttaaacacg 2089501 tttatcccat tcttcggcct atggtttctt gcttatctca gcctcgatgt ctcctatctt 2089561 cttacgttag cattaacggt gattgccgca ggttttctga caagaatttt tatcatcttc 2089621 catgactgct gccatcaatc ttttttcaaa caaaaacgct ataaccacat tctcggtttt 2089681 ctgacaggtg tcctgacttt attcccgtat cttcaatggc agcacagcca ttcgattcat 2089741 catgcaacta gcagcaatct ggataaacgc ggaacaggag acatctggat gttaacagta 2089801 aacgaatata aagctgcatc cagacgaaca aagcttgcat acagacttta tagaaacccg 2089861 tttatcatgt ttattctcgg accgatttat gtttttctga tcacgaaccg ttttaacaaa 2089921 aaaggcgcaa gacgcaagga acgtgtaaac acatacctta cgaatctggc aattgtcgcg 2089981 ttggctgccg cttgctgtct gatctttggc tggcaatcgt ttttactggt gcaaggcccg 2090041 atatttctga tttcaggttc aatcggtgtt tggctgtttt atgtgcagca tacctttgaa 2090101 gattcttatt ttgaagcgga tgaaaactgg agctacgttc aggctgctgt tgaaggcagc 2090161 tcattttata aactcccgaa actgcttcaa tggctaacag gcaatattgg ttaccaccac 2090221 gttcatcatt tgagtccaaa ggtgcctaac tataagcttg aagttgctca tgaacatcac 2090281 gaaccattaa aaaacgtacc gacaatcacc ttaaaaacaa gcctgcaatc acttgcgttc 2090341 cgtctatggg atgaagataa caaacagttt gtgtcatttc gggctataaa acatatacct 2090401 gtaagccttc cgcctgattc accagaaaaa cagaagctgc ggaagaatgc ctgatgataa 2090461 aggaggtctt ctaatatact agaaggcttc ctttttattg ttggagggtg cattctggct 2090521 ttcacaatga taaagttaca agtaagatga aaagctgaaa atgaggtaag atcatgatta 2090581 aaaatcattt tacatttcaa aaactaaacg ggattacgcc ctatatatgg acgatatttt 2090641 tcatcctccc cttctacttt atatggaaat catcatctac atttgttatt attgtcggca 2090701 tcattttgac gcttttattt ttttcggtat atcgatttgc ttttgtctca aaaggctgga 2090761 ccatttattt gtggggattt ttattaattg gcatttcaac cgcctccatt actctgttca 2090821 gttatattta ttttgctttc tttattgctt attttattgg aaacattaag gaacgcgtcc 2090881 cttttcatat tttatattat gtccatttaa taagcgcggc cgtcgcagcc aatttcagtc 2090941 tcgtattaaa aaaggaattc tttctgacac aaattccttt tgtcgttatt accctcatca 2091001 gcgcaatttt attgcccttc agtataaaaa gccgcaagga gcgcgaacga cttgaagaaa 2091061 agctcgagga tgcaaatgaa cggattgcag aactggtaaa attagaagaa cgtcagcgaa 2091121 ttgcccgcga tctccatgat acgcttgggc aaaagctttc tcttattggt ttaaaaagcg 2091181 acttagcaag aaaattgata tacaaagatc ccgaacaagc agctcgtgaa ctgaaaagtg 2091241 ttcagcaaac agcgcgaact tctttaaatg aagtaagaaa aatcgtttcc tctatgaagg 2091301 gcatccggct caaggatgaa ttgatcaaca tcaaacaaat tctcgaagca gctgacatta 2091361 tgtttatcta tgaagaagag aaatggcccg agaatatctc attgctgaat gaaaacattt 2091421 tgagcatgtg cttaaaggaa gctgtcacaa atgtcgtcaa acacagccag gctaaaactt 2091481 gccgagttga cattcagcag ctctggaagg aagttgtgat tacagtgtct gacgatggaa 2091541 cattcaaagg agaagaaaat tccttttcaa aaggacatgg cttactcggg atgagagaac 2091601 ggcttgagtt tgcaaacgga agccttcaca tcgataccga aaacgggacc aagcttacca 2091661 tggcaattcc taataattca aaataaacat aaaggatggc ttatatgatt agtatattta 2091721 ttgcagaaga tcagcaaatg ctgctgggcg ctttaggatc acttctaaac ctcgaagacg 2091781 atatggaagt cgtaggcaaa ggtacaaccg gccaagatgc tgttgatttt gtcaaaaaac 2091841 gccagcctga tgtatgtatt atggacattg aaatgcccgg aaaaacaggg cttgaagctg 2091901 ctgaggagct aaaagataca ggctgcaaaa ttatcatctt aaccaccttc gccagacccg 2091961 gttactttca gagagctatt aaagctggcg ttaaaggcta tttgttaaaa gacagtccga 2092021 gtgaagagct ggccaacgcc atccgtagcg tcatgaacgg aaaacgcatc tatgcacctg 2092081 aactgatgga ggacttatac agcgaagcta accctcttac agatagagaa aaagaagtgc 2092141 tcgaacttgt ggctgacggt aaaaacacaa aagaaatcgc tcaggaactc agcatcaaaa 2092201 gcgggacggt gcggaattat atctcaatga ttctagaaaa gcttgaagtg aaaaatcgaa 2092261 ttgaagccat tacccggtca aaagaaaaag gctggtttaa ataaaaaagg atcttggcat 2092321 ctgccaggat cctttttgtt aacctgaaat tcccgtttga gaacctcgtc gcaaccagaa 2092381 ttaaattgat ccatatcctc gctcctacgc ccgctgaacg attgtttggt taacagccca 2092441 ataaaagact ggattgaatg atatccctgt taaaatggtc ggccattgca catcagcaga 2092501 atttctgata ttgattatat tgtattttca gtatgacaaa gttgtgccac ttcgctcccg 2092561 aagctgccat gcccaactgc aagagcctaa tatcacaata aaaaaccgtc tgaaatcaat 2092621 ccgattccgt aaatggtatc tgctacatcc aactgcttat tatctgccaa aaacaccagc 2092681 tcgtttcgct gatcaaagat agtaacaacc agctataaat gtcatgatgc cgaatgtctc 2092741 tgtaatgtgg aatcaatctt ttaacccgag agcccctgaa tcgcacataa agaaaaacgg 2092801 gaccactttc ttttatcagc atatgatata aacagctcta agcagaacaa aaaaagacac 2092861 aagccaaaag cttatgtctt ttatcacaat ctatattatt agtttaagac tttaacactt 2092921 acagttttga cgccccaatt agaagcatca cttttacttg gtacaaatac gtcgatttta 2092981 tttcctttaa tagcgccgcc agtgtctgct gctgttgctt ccccgtagcc ttcaacatag 2093041 actttagaac ctagcggaat tacattagga tcaaccgcaa taactttcgc gttcgggttc 2093101 ttatttaagt caatgcctgt agctgtaacg ccggaaatgc cgccgtcgtt agcagtgtaa 2093161 gcagtagcag taactgttag ttcttttgaa gcttcttgat tatttgtatt tgattgaaca 2093221 gccttctcct ctgtgttaac agaagtttct gcctcagcct ttgtttcttg tttaggttgc 2093281 tgttgtacag cttcttgttt aggttgctct ttttgcacag cctcttgttt tggcgcagct 2093341 tgaggtgcgt ttgtttgcgc attctcagta gctgtgtttg ctgctgttgc ctgacctttt 2093401 actgaaagag ttgatccagc atagatcatg tcagagctta agttattcca aactttcagg 2093461 ttgttgactg tcgtgccgaa tttttgagca atcttagaaa gcgtatctcc cgctttaatt 2093521 gtatattgcc cagtcgtggt tgtttcttct gaagaaatgg tcagtttttc tcctgcaatg 2093581 attttatcag aagttaactt gttccattct tttaagtcct ttaggttcac tccatttttc 2093641 tgagagattc cccagagcgt atcacccttt tgcaccgtaa tttcttttgc agaagcgtga 2093701 gctccgaatg cagttgttga aagtgcagca actgccacaa aggacataat cgtcttcttc 2093761 ataagtaaat cctcccttgt tagcttttta ttggcggcta acaggtgata tcgtaacaca 2093821 cgtaaatgtc aaatcaataa caaaaagata tgatttagat tacagttcct ttacatgaag 2093881 gatttctctc tgatggaaag acttgctgaa cccttgatat aataggcttc gcaggtcttt 2093941 ttattttgag gcgaaacaga gaaaataaaa tgtgtttttt atagaaaaaa agattgtttt 2094001 tctgtttttt tagtctgtca tccttgcata agcctgtatt tcttgtaaaa aaagccggcc 2094061 gtattttgct cttttttgtt ctccgactcc ttttatagac aaaagttcat catcatttac 2094121 gggctgtttt cctgacattt cttttaacgt ttggtcagag aaaacaacaa atggcggaac 2094181 accctgctca gccgcaattt ctttccgaac catgcgcaat cgttcaaata gctcgtcatt 2094241 ttcagtaatc gctgccgctt ttaacgcttc ttttctcgct actgataatt ctcctttcag 2094301 cacattcctt cctttactgc tgacaaaaag agtcggaaac gttccgtctg acatcctgat 2094361 gaagtcgtca gaaataagaa attcgataaa atcactgatt tcgccaacgg attggtgttt 2094421 taatatcccg tatgttgaaa ggtcggaaaa gccgttttca agaacttttt tatttttgga 2094481 gccggcaagc acctgggcaa ccatcgtctt gccaaaccgt tctttcatgc gaatgataca 2094541 agataagacc atttgcgcct cccgcgtcac gtcatgggcc gctcttgtat cggtacagtt 2094601 tccgcactgt ccgcacgcat caggctcctt ttctccgaaa tacataagga taaaacgctg 2094661 cagacaatct tccgtatgac agtagtcgac catttgtctc agctttttta aatcctgctt 2094721 ttgtttctct tcatgttctg attgctcaat taagaagcgc tgcaccataa tatcctgcgg 2094781 tgaaaacagg agaacacatt cactggcaag accgtcccgt ccagctcgtc ctgcctcttg 2094841 ataatagctt tccatatctt tcgggatttg tgcatgcaga acaaatctga tatttgattt 2094901 atcaataccc attccaaaag cagaggttgc caccatcact tgaagctcat cattaagaaa 2094961 tctttcctgc tgctcttttc tcacatcatc agccaaacct ccatgatacc ggcctgccct 2095021 gacctgattt cgtttcaatc tctcatatat ccgatcagct tcttttctgg tcgctgtata 2095081 gacaattcct gcttcatgcc tgttgttttg cacatattcg tctataaacc gatctttatt 2095141 ttctcctttt actactttaa aggttaaatt ctctcgggaa aatccggtat ataccgtgtt 2095201 ttctttttga atatgcagct gtttgcaaat atcatcatga acctcgggtg tggctgttgc 2095261 tgttaacgcc atgatgacag gcttgtcgtg taattcacgg aacaagattt caatattcct 2095321 gtagcttggc ctgaaatcat ggccccattg agaaatacaa tgcgcctcgt ctattgcgac 2095381 caaaggaaca tctatgccct gcaaaatccg gataaactct atggacgtta gtcgctctgg 2095441 tgtaatgtaa aaaagcttat aagccccttc tttgagtccg ttcagcctct catatatttc 2095501 ctgattggat tgtgtgctgt taatgtaggc ggcgttaatc cccgcttctt ctaacgcatc 2095561 aacttgatcc ttcatcaagg aaatcaacgg tgaaatgacg atcgtcgtcc cttcaaacat 2095621 taatgccgga atctgatagc aaatcgattt gccgcctccc gtcggcataa tgcaggccgt 2095681 attttgcctc gcttccgtca ccaagcggat cgcttcatct tggccgctcc gaaacttctc 2095741 ataaccaaaa taatgagcca gaagggattg ggctctatgt aacataacgt gtaaacctcg 2095801 cttttccttg aatttctccc atcatatcat aaaaaagcgg ccttcatttc tttcacacaa 2095861 aaatggaata ttcactatac caaacctttt tagataaaat aaaaagccat ttccgaaaag 2095921 gaaatggctt tcgctacgtc ttgccgtatg caagtaagaa agttttaaac caccactcct 2095981 caaagtgggt gtttgcagaa acgttcctgt cgtcctctgc aatggaggca tgacattccg 2096041 gcttcgatat aaaactccct attacagctt aaaggttaaa acttaattaa caatacgcac 2096101 aaagtagctt ctttaatata gtacaccatc aggcgctttt aatcaagagg tcagaacaat 2096161 tgtttagaaa aactttttcc agtgaataaa actgtttttt ctccaaaata cctgacaatt 2096221 cgacaaacaa aaaatatatt acaataaaaa aaatagcctt tattgctaaa agcgaatgat 2096281 tattttcttc tatattaatg tgtatataca aaaagactcc tatttgtaac gataggagtc 2096341 ttggctttat tagaattttg cagcaagatc ttttgcttct tgtaaacctt tttcaacgat 2096401 ttcttgcgct tgatcaggtg ctgcgttatg tccttcgatg acaactgtgt gcaagtcttg 2096461 aacaccccag aaaccaagaa ctgttttcat gaagtttaat gacatttcaa gtgcagccat 2096521 tggtccttct gagtagacac cgccgcgagc gttaagaagc gcaacttttt tgccgcccat 2096581 taaaccgact ggtccttctt gtgtgtattt gaatgtaacg cctgcgcgag acagataatc 2096641 aacataagta tgaagcactg ctggcactgt gaagttccaa agcgggaatg cgaaaacaac 2096701 tttgtcagct tttacaaact ggttcagata tttgtcagca attgctgctt gttttttctc 2096761 atcttctgtc atttccattc cttgacctgc tttaaatgtt ccgttaatca tatctctgcc 2096821 aaggtaagga aggttttcct tatgaagatc taattcaacc acttcatcat tagggttgtt 2096881 ttctttataa gcagctaaga aagcttcgta aagtttagtt gaaacgcctt cttcagctgt 2096941 acggtcgctt gattttacaa ataaaactgt agacatttgt attcctcccg gtaaactttt 2097001 tatatttact tacaaatagt atgttacttt cttttttacg taaagtcaat cactttattt 2097061 tgaatatgag attttttttc aaaaaaagca agtacatcta atatcggtgt acttgcttgg 2097121 catttttact tcgaatcttg ttcacgatcc aagatttcat acgtctgcga gcttttttga 2097181 tcaattgttt ctttgttgga taagtctttt acctgttcat gaaactctct ttcataagaa 2097241 ggagcatctg tctccagatc atcctccaca tcagcttggg cctcaactgt cattcttgca 2097301 taaggaacag cttcaagtct ttcgtaagga atctcttggc cggttttttc acacacgcca 2097361 taagttccgt ctttcatctt ttgtaatgca cggttgacct cctctaacag ctcccggtca 2097421 atctctttca ctgtttggtc tgtcatccgg tctgtgacga gcgtcccgtg gtctgccata 2097481 tggttgtcaa ccccattgga aagctccccc acttcttccg tcattgattc tgtttccttt 2097541 ttctcgccag acaattcttt ttgcatatcg agcaatttat gatagagatg ctgtgtttgt 2097601 tcttttgtca gtgccatgta tatcctctcc tttctatcct gtttcccgtt ttgccttctg 2097661 tcaaacatgg aaacatcgat ggaaagatga gctactgcct ttttgaacgg atcgtgaccg 2097721 ctggcgtcga tggtgcttcg ggttttcgtt ggcacttttt gtccttctct tctggcggta 2097781 tataataggt tgcgcctata tttaatctgc cgctcagttc atcaatggtc agctcgccga 2097841 attcaagatg atagtcaact ttttcgacat tcagcgtttc aatatgtata taggtttctt 2097901 cagactcttg tttgctgctt tgtttttgtt tctcaatcac tgagagtctt tcttcacatt 2097961 cacgcagttt gtcaagttct ggtttcaagc aatgcctgat cagcgaccgg aacatttttt 2098021 tcatgacatc acgacccttt gcatactcct ctttcgtcta catatataat gaggtatatc 2098081 ccatagaaag gagaggtttt catgcttccg actaacatca atatttctca tctcaagact 2098141 aactcgatag gcaccggctc atcccttacc tttggttctg cggagttaag gaacaggtgc 2098201 tctgctatca aaagaaataa cggttttggg gaacaaaatg cagatggtat tgttatggtc 2098261 attccgattg aatcaattga tgaccgtgat gtgtcagatg cactcagtat gaaaatcaat 2098321 catcaataac aatggttttc gcttgacctt cgtctttttg aatagtgatg tataggattc 2098381 cgtctttaaa aatggcattc atctttccat gaagatgatc ggaaagcgga attttctttt 2098441 caaaacttcc gtatttccct tctttttggc gaaagtcctg ttcattaaaa taggaaaagc 2098501 gctgcccctt caccactaaa taatctccgt acgataatat gtgaacgtct tgtttacggt 2098561 agcctggaag ataaattaaa aactgcactt ccgcaacggt atctacaata tccatgctcg 2098621 gaaatgaagc atctcctttc cctcgctgat cttgctgcgc aaacggaaac ggagattggc 2098681 catttgtcat aaaaggggtt ttttggtctt catcaaatac ctgtttccaa aagtcaccgc 2098741 cgtacatctg ctgtgcgaat tccatccact gcttcatctt ttcgaaatcc atttgaagcc 2098801 ccctgtctta acatacttta taaccgccag catacaacta tagaaaggag gtttgcctgt 2098861 ggttcaacca actccgtata tcaatattaa tattttcatg ctgaaaatta attcctttga 2098921 aaatgcttca gcggttaacg taggacaaaa tttattggca gaatggcaaa attcagataa 2098981 aaaaaatcaa ggctacggac agaattttgg agatgcgagc ggatttatgg gcacgagaag 2099041 ccatgtggat gacagagacc aaattgattc tccggcctct tttgaaagtg aagcggttaa 2099101 ctcctcaatc aaaaggaagt gatgagatgt tcttttcacc ctccgtcgta aatgtcggcg 2099161 gatttaaaat caatacgatg gatcgaggtt cctctttaac actcggtccg tatcagcagg 2099221 tcgattactt tttatcagct aaaataaatc aagggtttgg agaagaaaat ggcgacttta 2099281 ctcctcttgt cgtgccgatt tcaaatgtat tagatgcaga tcttgttgat tcgaactcag 2099341 cgaaaaacag tgtggtgtaa taagaacagg gcgcacatgc cctgttcttg tttttatata 2099401 taaaaaaagc ctaaccattt tttgaacggc tggctcatca aatattcagc tgcacaaatg 2099461 ctttgtcagc accgcctgaa cctcgcttaa atcggtgtct ttcgcaaatt ctaattcgaa 2099521 agttttgctt cttgtcatca ataaaagccc agtgtccgga tcaaacattc ccgcttcttg 2099581 gatggcaaag ctttcaattg ttttatatgg aagaaataca cgaaccttct ttttagaaaa 2099641 cattttattg tcaaagaaaa tgatccgctt atttgtaaag caaatttggt ccactcggag 2099701 cttataaatc gattcaattc tttccccttc aacgagcaaa gcctcaagct tctttgcgtc 2099761 cgttgatctg ctaacagaaa aaatacccaa tgaagaaccc ctctttctgc atttatctat 2099821 ttgttttatc attcactaca taaaaataag tcctttatcc ctatataaga atacgacata 2099881 gaagacattt aaaccattac gaacagatta catttttcaa atttttgatt tgttttttgg 2099941 cttttaagct gttgtcatca agtaatacgc acatatagag aaaaaagttt caatattcag 2100001 caatgttttt ataaaaaagt ggtttttaat gattttttta attttgtttt atatttcctg 2100061 ttttaaccac aaaaaaaccg cagctgagct gcggttttat gtatcgactg cttttaacaa 2100121 aatctgtttg atgcttcaag gaagcattac atctcttcga agtattcttt ataatagccg 2100181 ccgactttat tcgtattgtc gaccacaaag agaaactcct ctgtttcatt ttttacttca 2100241 tattcttttc ccggcgttaa aacgcggttt acgatatatt tttttgcgtt tgtctgcaca 2100301 cactttactt ttttaatggt ttctttttca agccaatttt tatgaatcat gatgaaatct 2100361 ccttttctta tctataagct tattgtagct tttttctttt gtaaattgca atatcggtta 2100421 ttcattgatt ttgccttgat ttctattata gaatgtttgt atacgcttac gtttgaagca 2100481 actatcacag cttatttctg ctattcaatc caggaatcaa tgtgctatca ccaagaatct 2100541 cagaacagac cataaaaaat gactggaggt ttgttacgga tgagttcttt aacgatgcaa 2100601 gtgacgaaaa ggctggagac atttttacag ggaacaaaga agctttatat tgacggaaag 2100661 tttgttccga gtgcctcagg ggcaaccttt gacactccaa acccggcgac cggcgaaacc 2100721 ttgatgacgc tgtatgaagc ccaggctgcg gatgtggaca aagctgttaa agctgcccgg 2100781 aaagcctttg accaaggtga atggagaaca atgtctccag cttcgagaag cagactgatg 2100841 tataagctgg cagacttaat ggaagagcat aaaactgagc ttgctcagct tgaaacactt 2100901 gataatggga aaccgatcaa tgaaacgact aatggagata ttccgctggc tattgagcat 2100961 atgcgctatt acgccggctg gtgtacaaaa ataacaggac agacgattcc ggtttccggc 2101021 gcttatttta attatacgcg tcatgagcct gtcggtgtcg tcggccagat cattccatgg 2101081 aatttcccgc tcctgatggc gatgtggaaa atgggcgcgg cacttgcaac aggctgtaca 2101141 atcgtcctca aaccggctga acaaacaccg ctttcagctc tttatttggc agaattaatt 2101201 gaccaagccg gtttccctgc cggtgtaatc aacatcatcc caggattcgg tgaagatgcg 2101261 ggagaagcgc tgacgaacca cgaagcggtt gataaaattg cctttaccgg ttccactgaa 2101321 atcggaaaga aaatcatgtc caccgcagcg aaaagcatta agcgtgtgac attggagctg 2101381 ggcggaaaat cgcctaatat tcttctgccg gatgcgaatt taaaaaaagc catcccgggc 2101441 gctttaaacg gtgtgatgtt taaccagggc caagtctgct gtgcgggctc acgtgtcttc 2101501 attcataaag accaatatga tgaagttgtt gatgaaatgg catcctatgc tgagtcactc 2101561 cgccaaggag cgggacttca taaagatact caaatcgggc ctctcgtaag caaggaacag 2101621 catgagcgcg ttctttccta tattcaaaaa ggaaaagatg aaggagcaaa agcagtgacc 2101681 ggcggaagct gtccttttga agcaggatat tttgtcgcac cgactgtgtt tgcgaatgtt 2101741 gaagacgaaa tgaccatcgc aaaagaagaa attttcggac ccgtgctgac tgcaattccg 2101801 tacgaaacag tcgatgaagt tattgaacgg gcaaaccatt cagaatatgg gcttgcagcc 2101861 ggactatgga cagagaacgt caagcaggct cactatatcg cggaccgact tcaagccgga 2101921 accgtttggg tcaactgcta taatgtgttt gacgcggcgt ctccatttgg cggttataaa 2101981 cagtcaggac tcggacgaga aatgggatca tatgccttgg ataattacac agaagtcaaa 2102041 agtgtatggg taaaccttga agactaacat gtatgtttaa aaaactgctg cctgccagca 2102101 gtttttttct ttctgtaatg gcagtaaaag acgctgaata tatatgcttc tgaaggagtt 2102161 gagcgtgatg ggcacacttc aggagaaagt gaggcgtttt caaaagaaaa ccattaccga 2102221 gttaagagac aggcaaaatg ctgatggttc atggacattt tgctttgaag gaccaatcat 2102281 gacaaattcc ttttttattt tgctccttac ctcactagat gaaggcgaaa atgaaaaaga 2102341 actgatatca tcccttgcag ccggcattca tgcaaaacag cagccagacg gcacatttat 2102401 caactatccc gatgaaacgc gcggaaatct aacggctacc gtccaaggat atgtcgggat 2102461 gctggcttca ggatgttttc acagaactga gccgcacatg aagaaagctg aacaatttat 2102521 catctcacat ggcggtttga gacatgttca ttttatgaca aaatggatgc ttgccgcgaa 2102581 cgggctttat ccttggcctg ctttgtattt accattatca ctcatggcgc tccccccaac 2102641 attgccgatt catttctatc agttcagctc atatgcccgt attcattttg ctcctatggc 2102701 tgtaacactc aatcagcgat ttgtccttat taaccgcaat atttcatctc ttcaccatct 2102761 cgatccgcac atgacaaaaa atcctttcac ttggcttcgg tctgatgctt tcgaagaaag 2102821 agatctcacg tctattttgt tacattggaa acgcgttttt catgcaccat ttgcttttca 2102881 gcagctgggc ctacagacag ctaaaacgta tatgctggac cggattgaaa aagatggaac 2102941 attatacagc tatgcgagcg caaccatata tatggtttac agccttctgt cacttggtgt 2103001 gtcacgctat tctcctatta tcaggagggc gattaccggc attaaatcac tggtgactaa 2103061 atgcaacggg attccttatc tggaaaactc tacttcaact gtttgggata cagctttaat 2103121 aagctatgcc cttcaaaaaa atggtgtgac cgaaacggat ggctctgtta caaaagcagc 2103181 cgactttttg ctagaacgcc agcataccaa aatagcagat tggtctgtca aaaatccaaa 2103241 ttcagttcct ggcggctggg ggttttcaaa cattaataca aataaccctg actgtgacga 2103301 cactacagcc gttttaaagg cgattccccg caatcattct cctgcagcat gggagcgggg 2103361 ggtatcttgg cttttatcga tgcaaaacaa tgacggcgga ttttctgctt tcgaaaaaaa 2103421 tgtgaaccat ccactgatcc gccttctgcc gcttgaatcc gccgaggacg ctgcagttga 2103481 cccttcaacc gccgacctca ccggacgtgt actgcacttt ttaggcgaga aagttggctt 2103541 cacagaaaaa catcaacata ttcaacgcgc agtgaagtgg cttttcgaac atcaggaaca 2103601 aaatgggtct tggtacggca gatggggtgt ttgctacatt tacggcactt gggctgctct 2103661 tactggtatg catgcatgcg gggttgaccg aaagcatccc ggtatacaaa aggctctgcg 2103721 ttggctcaaa tccatacaaa atgatgacgg aagctgggga gaatcctgca aaagcgccga 2103781 aatcaaaaca tatgtaccgc ttcatagagg aaccattgta caaacggcct gggctttaga 2103841 cgctttgctc acatatgaaa attccgaaca tccgtctgtt gtgaaaggca tgcaatacct 2103901 taccgacagc agttcgcata gcgccgatag cctcgcgtat ccagcaggga tcggattgcc 2103961 gaagcaattt tatattcgct atcacagtta tccatatgta ttctctttgc tggctgtcgg 2104021 gaagtattta gattctattg aaaaggagac agcaaatgaa acgtgaatct tatcaagcgg 2104081 agatgttcaa ttggtgtgaa gccctgaaag atcagattca aaagcgaggt cagcttgacc 2104141 agtttgaaga tcaaatcgac aagatgattg aggctctgga agatgaccaa acaacagaag 2104201 aagattggta taaacaggcc gctgcccttt atcgggatat tacagaatca gatgatacaa 2104261 gtgaaagacg cgcttatgtc cctataggga aacacgtgct gccaaagctt ccttacaaat 2104321 actccgcctt agaaccttat atatcacgcg atattatgat ccttcatcat acaaaacatc 2104381 atcaaagcta tgtcgatggc ctgaacaaag cagaatcaga gcttaaaaaa gcgagagcga 2104441 caaagaatta tgacttaatc actcattggg aaagagagct tgcgttccat ggagcaggcc 2104501 attatttgca tagtattttt tggttttcta tgcatccaaa cggaaaacgg cgtcctacag 2104561 gggcattgtt ccaaatgata gacctttcat ttggaagcta ttccgctttt aaagaacatt 2104621 ttacccaggc ctctaaaaaa gtggaaggcg tcggctgggc cattctggtc tgggcacctc 2104681 gatcaggacg gctggagatt ttaacggcag aaaaacacca gctctttagc caatgggatg 2104741 tgatccccct tttaccgctt gacgtatggg agcatgccta ctatttgcaa tacaaaaatg 2104801 accgggccag ctatgtcgat cactggtgga atgtcgtgga ttggcgcgag gctgaaaaac 2104861 gttttgagca ggcaaaagaa gtcgtttgga agctctatta aaaaaagccc cctttcctcg 2104921 ggggcttcgt gtgttaaaaa atacctatca catgcaaaaa cacgatgatg atggcaacag 2104981 gagatagata tcgaatgagc agcagccaaa ccgcaaacca ctttcgtttg agattggaac 2105041 cgcttttcag ctcgtcaaac aaatcctgtt tcggtatttt tagcggaaca aaaatcgaaa 2105101 tcagtaacgc acctaacggc attaaaatat tgctcacaag atagtcagcc gcatcaaaaa 2105161 tagacagatg aaatatagtg acgtcactta agacaccgta tgataatgca gacggcacac 2105221 cgacaataaa aatagcaata ccgcctaacc aagcgaatcg ttttctctta ttgatatcgc 2105281 ctttcgacag tactgcgacc aaaatttcca gcattgaaaa agcagatgtc aatgcagcaa 2105341 ataaaaatag aagtaaaaat gctaataaaa agataattcc gaacggcatt tgattaaaca 2105401 cagtcggcag aacgttaaat aacagaaccg ggccttggtc tggcttgagg ccgaatgaaa 2105461 atacagctgg aaaaatcgca attccggcca ttacagcaac aagcatgttc ataacagtta 2105521 cagatacagc ggactgtacc agattttcct gtttctctaa ataagcgcta tacgttacca 2105581 tgacagatac accgacactt aataagaaaa aggattgtcc cattgcatat aaaatggtat 2105641 tggcatcaat tgcagttaaa tcaggcatga ggaaaaattt gattccttcc atcgcgccat 2105701 caagtgtaac cgaacgcacc attaaaatga tgaataatag aaaaagcgcc ggcattaata 2105761 cttggcttgc tttttcaatt ccgctgctta ccccttttgc aacaactaaa attgttacca 2105821 ccataaagag cagctggcct cctacagcca aataaggatt tgaaatggta cttgcaaata 2105881 tcgtatcaaa accagatgtt tgcgataaac cgccagtgaa gccttttata atataaatta 2105941 aaatccatcc gcctacgaca ctgtagaaag atagaagaat aaagcacgtc accatgccta 2106001 aataaccgat ccaatgccac ttcgttcctg gagcaagtgt tttataggac tgaacggcat 2106061 ctttctgtgt tcttctgcct atgatgaatt cacctaacaa taaaggcagt ccgattaaaa 2106121 ccgtaaataa aataaaaata agtaaaaatg cgcctcctcc gctggttccg gcaacatatg 2106181 ggaatttcca tatcgcacca agcccgatag ctgatcctgc cgcggctaaa ataaagccga 2106241 gcttcgaaga ccattgattt gcttccttca ccgtatcact cctatttgat ctaaccatta 2106301 taaaggttca ttgtaagaat atcttcctat atagtcaaga acattttaat tagtttacat 2106361 catatatcta tagacatctg ccaaaaacta atattgaatt attcagaaaa ttatttataa 2106421 taagagaatg ttatgaaatt tgtaagaatt tctgctgaag ttcttgataa gtgtgttagg 2106481 agtgttttta tggacatcat tagaaaaata agccattttg caggacaaac ctttggcata 2106541 tgggtcattg tttttgcagt gctgggattt tctttcccat ctttatttac gtggatcagt 2106601 tcttatatta cgatttttct cggcattatc atgtttggga tgggccttac actgcaagcc 2106661 gatgatttca aagagctggt cagaaagcct tggcaagtta ttattggagt aatagctcag 2106721 tatacgatca tgccgctcgt tgctttcggc ctcgcatttg ggcttcatct tccagctgaa 2106781 atcgcagttg gtgttattct tgtcggctgc tgtcccgggg gaactgcatc taatgttatg 2106841 acattcttag caaaaggaaa tactgccctt tctgttgcgg ttacgacaat ttctacctta 2106901 ttggcacctg ttgtaacacc gttgttgatt atgctgtttg ccaaagaatg gcttcctgtc 2106961 tcgccggggt ctttgtttat ctcaatctta caggcggttt tatttccgat cattgcaggt 2107021 ctgattgtca aaatgttttt cagaaaacaa gtggcaaaag ccgtacatgc ccttccgctt 2107081 gtttctgtca ttggcatcgt tgcgattgtc tcagctgtcg tcagcggcaa tcgggaaaat 2107141 ctgcttcaat cggggttgct cattttttca gttgttatcc tgcataacgg tatcggttat 2107201 ttactggggt ttctttgtgc aaagctttta aaaatggatt acccgtctca aaaagcgatt 2107261 gcaatcgaag tcggcatgca aaactccggg cttggggctg cacttgccac ggctcatttc 2107321 tcaccgctat ctgccgtacc aagcgcaata ttcagtgtgt ggcataacct ttcaggttct 2107381 atgcttgcaa catattggtc aaaaaaagtg aaaaagaagc aagctggatc caaaagcagc 2107441 aatctatcac tttaaatatg catcaaaaag ggtacatcac tttatcgtga tgtacccttt 2107501 tttattatcc ttctaataaa agctgttcag gatcttccag taaatttttg attgtcacga 2107561 ggaaaccaac cgcttcttta ccgtctacaa ttcggtgatc ataagataaa gcgatataca 2107621 tcatcggacg gttttcgaaa cgctcttcat caatggctac agggcgcagc tgaatcttat 2107681 gcatgcccag tataccgact tgcgggctgt ttaaaattgg agttgacatc aatgaaccga 2107741 aagtccctcc gtttgtaatc gtgaaggagc ctccctgaag ctcgctaagg gttaatttat 2107801 tgtttcttgc ttttttcgca agctcgccga tctctttttc gattcctgca aatgtcaggc 2107861 gatccgcatc ccgtacaacc ggaacgacaa gaccttcatc agcagcaaca gcgattccga 2107921 tatcgtagaa ttttttaacg atcaactcat cgccttgaat ttctgcattc aacagcggat 2107981 attttttcaa tgcagccacg accgctttcg tgaagaaaga cataaagccg agcttcactt 2108041 cattttgctc aaaaaattga tctttgcggc gttttctgag attcatgaca gccgtcatgt 2108101 ccacttcatt aaatgtagtc agcatcgctg atgtttgctg tacctctaca aggcgttttg 2108161 caatcgtttg tctgcggcgt gacatttttt gcacttcaac aggtttgtca aagctttgct 2108221 gtgctttttg agcctgaggc tgctgctttt gctgaggagc cggttttgat gccggttttt 2108281 cgtacgcttc gacatcctgc ttgcgcactc ttccaagcgg atctccagtt ggaacttgag 2108341 acaggtcaat tcctttttct ctcgcaagct tacgggccga cggagaagcg atcgttcttg 2108401 attttgcttc agattgtgct tcctcgctca cctcttgtgc agctggttca gcctgtttct 2108461 cttcttttac gctttccttg ctttctgttt tctctgtagg agcaggggca gaactttcac 2108521 ccgcgccttc tgaaatcgta ccgataattt ctccgacctg gacggtatca cccgaatctt 2108581 tcaatacctc ttgaagtaca cccgattctt ctgctgtcaa ttcaacattc actttatccg 2108641 tttctagttc aagcagatat tcaccctgtt ctacatagtc accaggctgc tttaaccatt 2108701 gggctattgt tccttctgag attgattctg ctaattcagg taccttaatt tccgccattt 2108761 tttcatttcc cccttagttt ttgcgagtca agctatcaga tacaatacgt tcctgttctt 2108821 ttttatgaac tgtcggatct ccctctgcag ggctggatcg tcttcttcgt ccaatatatt 2108881 gaacgcttac tccctctggt gcaatctctg tcaaatacgg gctgatataa ccccaagccc 2108941 ccatgttctg cggctcttcc tgcacccaaa cgatttcttt caggttcgga agttttgcaa 2109001 ataattcttt gactcctttt gccgggaatg gatacagctg ttcgattctc gcaatgtgaa 2109061 gccactcttt accgtcttct aacttattaa aatgatcgct aatgtctata gacactttac 2109121 cgctggataa tacaagtctg gttacttttt catagtcatg agaaagtccc gactgttcat 2109181 aaacaggctg gaagcggctt tcgctgagct cctgcacttc cgacaccgta tttgggttgc 2109241 gaagaaggct cttcggcgtc ataatgacga gcggtctgat ttcttcacga agcagcattt 2109301 tagcctgtct tcttaaaata tggaaatact gtgccgcgct tgtcaggttg gcaaccgtcc 2109361 agttgttttc cgctgcaagc tgcaggaatc gctcaattct tccgcttgag tgctcaggcc 2109421 cctgtccctc gtaaccgtgc gggagcagca tgactaatcc ggatttttgg ccccatttcg 2109481 cgcgtccggc agaaataaat tggtcaaaat acacttgagc agcgttggca aaatctccgt 2109541 actgtgcttc ccacaaaaca agcgtttccg gtgaatgcac gttatagccg tattcaaaac 2109601 cgagaaccga tccttcagac agcgggctgt tatgaacagc aaatgatgtg ctgcagtcag 2109661 ataagtgatg aagcggcaca aattctttgc ccgtctcact gtcatgaagc acaaggtttc 2109721 tttgggcgaa cgttccgcgc tcggaatcct gtcctgttaa acgaatcggt gttccgtctt 2109781 tcaaaattga agcaaacgcg agtgattctg ccaaagacca ttccactttt ctgtcatcat 2109841 cgaacgcctt ggcgcgtctt tctaaaatgc gctttagctt gccgaaaaca ttaaatgact 2109901 ccggccagtt gatcaattcg ccattcagct tgcggagcac atcaaaatca atcgaagtgt 2109961 ccacatctgg gaaaccgttt gatacaggct ctggaagttc aatttcacaa gcagtgtgtt 2110021 cctttttaga cggaactttc tgatatgcat cctcaatgcg cttcgttacc gatttttcga 2110081 tgttttgaac gacttcctcg gtaaccacgc cttcttttac cagcttttca gcgaaaattt 2110141 gtttgacggt cggatgcttt ctgacagcat catacagcat tggctgagtg gttgacggtt 2110201 catccatttc gttgtgtcca tagcgtctgt acccgatcaa atcaatcaga aaatccttgt 2110261 tgaatgtttt tcggtattcg accgcaaact taacagctga aagacaagct tcaggatcgt 2110321 ccgcattcac gtgaacaatc ggaatttcat aacccttggc caggtcgctg gcatattttg 2110381 tcgatctgga ttcagcgctt tctgttgtga atccgatcat gttattggcg ataatatgaa 2110441 tcgcaccgcc tacttgatac ccttttaaag agcttaaatt caatgtttca gctacaattc 2110501 cttccccagg gaatgcagcg tctccatgga ttaaaatggc cagcgatttt gtttcatctt 2110561 gtaccgggta tccgctttgt gttcgcgttt cctgtgccgc tcttgtgctg ccttcaacaa 2110621 tcggattgat aaattccaag tggctcgggt tgttcgctaa cgtaatgcgc gctgattttg 2110681 tttcagcgtc ttgaagctcc cgattcgccc ccaaatggta tttgacatcc cccgtccatc 2110741 cgtagctgat tccaatggat ccctcagacg gtacaagatc tttgttcggc gcatgctgga 2110801 attcagagaa gatgatttca tacggtttgc cgagcacatg tgccaagaca ttcaggcgtc 2110861 ccctgtgcgc catcccgatg ttgacacttg tcgtgcctga tttgacagat tgtgcaataa 2110921 tgtcatcaag cactggaaca agagcgtcca gaccctcaat ggaaaagcgc ttctgcccga 2110981 cgaatgtgcg gtgcaaaaac tgctcaaagc cctctacttc tgtcaatctt tccagcacag 2111041 ctgacagctt ttcagctgag ttcttctgga acagctcgcc agattcaatc tttcttgtca 2111101 gccactcgcg ctctttgaag tcatgcacat ggtcaaattc aaaagagatg gttcttttat 2111161 acgtatttcg taaatactga atggcttcta aaccgttcga aatgttttta ggagcgtctt 2111221 tgcagatgac agacgcaggt attgctttta tttcctcttc tgttagcccg taatcggata 2111281 atggaaaaag ttcgctcttt ttctcatcct ttctgagcgg attgacggaa gcgttcaaat 2111341 ggccataggt tcggatatct tctgcaagtc tgactgcgga tgcgatcttt tgaatcagat 2111401 cggctgtaac acgtcccttt tcttttgttc ccgaggcctc ttttatatcg cttggcggag 2111461 caccgagctc gtcgaacatt tccttcaaat ccgggtcaat gctgttcgga tcctgggtat 2111521 actgatcgta aagctccagc gcatagccga ggttcggacc gtaaaaatct tcccaattca 2111581 ttcgttgttt catactattt tgaaacattt gaatattacc cccaacttaa ataatcaagt 2111641 gattgattca ctatcttgaa ataactttcg aacgctgtgt ccaaaattat gtaataaaaa 2111701 cgcttccaac gatattttac cactgtttgc aatttgattc taccttgatt gttcacaaaa 2111761 tagtaaaaaa cctttataaa aaacaaaaaa tttaatcatt cgaaaaaaca aacgccaaaa 2111821 agcataggat taagggctat cctatgcttt tatgaagcag ttttttcagc agcggataca 2111881 aaacatccgg tagctgatca acatccggga caaatatact gaattttccg tacatatcct 2111941 ggatcgtctt catttgcgat tcttctattt ctgagttgga gagaaaaaca tttatcactt 2112001 ctattcctct ttttcgggct tcgataaccg cctcacttgt atcaacgatc ccattttgtt 2112061 cgtagccaaa tgcggccggc tctccatctg agaaaacaat taagaacttt tgcgcctcgc 2112121 tgcgatgcag catttttttc gtcatctgcc taattgcgta cccgtcacgg ttatcttctt 2112181 ctggctcaag ctgcataatg gccggtccag aatcttgtct taatgatgat tggaagggaa 2112241 taaccgtatt gaaatagttt ggctggcttt tttcggttgc atcatttgtg tcctcccaaa 2112301 aaccgacaat ctgatgcgga accgctaccg atttcaacgc ttcgtgaaac agcacgattc 2112361 ctcgttttgt ttcgtccatt ttgtcgaaca tgctggcgga acaatcgacc agcaatgtaa 2112421 aaactgcgtc gatttctgaa gatggttctt gctttttgta gaacaggcgc ggatttcgct 2112481 cagtgaagta acgaagaagc ttattgttca gtctcccggc atgaaggtct gttctcggca 2112541 atgttttttt atgctccagc gttttttgaa tcatttgttt caaacgcttt tgatacgatt 2112601 caatcgtttt tgcctgctgt ttataagaaa gctcttcttc actggttgcc ggctgcggtt 2112661 ctttataaat tggaaatgca tatttatttt ctttgccgtc agccataccc gctccgttcg 2112721 gctggtcttt ttgggactcc agcgcttcca gcttggaata gtctttccgt ttcgtttgtc 2112781 tggctgatcc ttgaacagag ccaagggcct gatctccatc gtcgccttcc cttgaagcat 2112841 cttttcctaa atctgatttt gcgccgtgtt caatatcaaa ttgaaggaag cttttagacg 2112901 gtgcttctgt ttcccggtgc catgtcggca tttcttcttc atggatatcc tcatcaccgt 2112961 ctgattgttt tggaagcgtg atgtcatcac tcagcttcgg cgcttttttc tcttcttcaa 2113021 ataacggctg ttctgcagct tttgcgtaat caagctcagg caaaaagaag taggtgttca 2113081 acatgtcttt atcgagtacc tcttcaagtc cgtccatgag gtcctcaaca attttcagaa 2113141 cctgccgtgt cgaatctgct tcatacacac gcaagagctg ctgctcaata aacgggcgca 2113201 tcagatcgat atcttcacgc atggatggaa gggtctcgag cggcgattcc gctgtgagct 2113261 tgaaatagat cgcgcaaaag agcgcatcgg taaaaatgct tcgttccaaa tttaaggtca 2113321 gctgggttga gaaatgtttt ctgtacatgt cttttcgctt cgcaaataca tgtttcgtac 2113381 ccgggcgctc acgtttgatg cattcttcga tcctaatgtc ttcaagcagc ataaagagct 2113441 gcttggcaaa acttttaaac gtaagatggc gatggatatc attcaaaaag ttcgcaaact 2113501 catgcagcga gctatatctt gttccgactg aacgcaggta gacgtcgctt ttcagacccg 2113561 cttccatgtc ctcagctgcc ctgtctttcc aaaagtggct catatagatt ttcttttcaa 2113621 atggattgta ataggactga acgccatact ccacttctac cgcttcactc ttggtgagtg 2113681 ttttggccaa atcagtcagc atcataaata aaaatgaatc aatcgtgctg tcgttaaatt 2113741 tgataaattt catcgcagcc ccctcattca aacagagttt ctgcaatatt tcggacagcc 2113801 gctttttccc gatcatcatc aagcttttct acaattcccc gctcaatggc acgacgcggc 2113861 ggaatataag cagctaaatc acatgtatcg attaaagctc tgatggatgc cgcttcttca 2113921 gacacctgtc cgttattggc ctgaacgatc aagtcagagg aaagcgtgat aaatctgtca 2113981 atcaatttct cgtctttcaa ggctgactga gacatgagca cttgtttcag cagctcgcct 2114041 ttaatataag gcacatcaat gatgacaaaa cggtttttca acgcttcatt cagaggaaca 2114101 gttccgacat agccttcatt gatggctgca atgactccga aaccgctttt agcccgtatg 2114161 acctcgcctg taaacggatt tgtcatcatt tttctgtaat ctaatacacc gtttagaata 2114221 ggcagtgttt ccggcttcgc catattgatt tcatctatat aaagaaaatg gccttccttc 2114281 attgcctttg taacaggtcc tgaaacaaac tcgattgttg cctggccaga ttgattttca 2114341 atcgttttat aaccgaccaa tgcctcagcg tccaagtcga ctgaacagtt gacgctgtgc 2114401 atcggtttat gaaaatagct ggacaatgtt tctgccagct ttgtttttcc tgaacctgta 2114461 ggccctttca gcaggacatt tttccccatg gctaatgcaa taatggcgtc aaataaaatg 2114521 gcttcatcct ccgcctcata gcctgatgtt cctataagcg attgaaactc tggggaaata 2114581 ggctgctctt tatatgataa aagcttttgt tgtatatctt ccggcaatgt taagtgctgt 2114641 agttgagttg tcatagacag attccctttc ctattcatat tccattaacg agtatactaa 2114701 aaaagcccct gtatgctcaa tacaaaaggg cctggatgat attactgctt ctcgttattt 2114761 cccaaaaggg ctccgcagac aatacgcgca ccggaattgc cgcttgggtt tgtcagataa 2114821 tcgtccgctt gttcatgaat aataaatgca cttccgtcct cgtcgagaat atttagttta 2114881 cttccttttt tcagtgaagt gtcaggcgca ttcattatga catctacctt tccatcagca 2114941 ccgacttcaa ggttcggcag atctccggca tgatgcccca tcggattatt aaagccgtgt 2115001 tctttgttca gtggattaaa gggaccgccc gctgattcaa aatccggcct gacacaagaa 2115061 cctttctcat aaatatgaaa accgagagaa gcacctggac gcaggctgtt tgcggaaata 2115121 tgaatatcga ggccttcatc atctgattct ttgatctcta taaaaccgac tgctttccct 2115181 tcacgattga ccagctggac atgatgacca aacgctgacg tttcaaccac ttttttttcc 2115241 ggcacccggt taggagggtc tggaggtttt ttttgtccgc atccggcaac tcccagtgcc 2115301 gtcagcatca tcaacagcaa gagacggtgc atactgtctc ccccttgttt tttctaacag 2115361 tgtggtcaat cattgtctgg tataaacaaa aaagcctata aaaggctttt tgtcatactc 2115421 atttttaaaa ataacttctt gcgcccaagt accgctgttt ccaatacgaa ttgctgagat 2115481 tggaaatgtc gacgcccgat gagcttgcat gaataaaatc accgccgcct agataaatcc 2115541 ccatgtgaga cgggccggat ttatatgtgg taaagaagac aaagtctcct actgacggct 2115601 ggctgacttt ctgcatgaca ttccaatacc ctgccgtact caatcttgat atagatgata 2115661 cattattaat gaggtaataa atgaagccgc tgcaatcaaa accggcaggc gtgtttccgc 2115721 cccatcggta aggcactccg acatattttt tcgcttccgt tatcattctg tcaatcttcg 2115781 aacctatttg aatgtttgac cctgagttat cttttggctt tgttggcttt gtcggatttg 2115841 aaggattaga ttttgatgct cccgaaatag tcagaacctg cccgatttgc aacacatccg 2115901 atgataaatt gtttttatca cggatgcttt ggacagtgac tccgagccga tttgcaattt 2115961 tccacagcga atcgcctgct tttaccttgt acgtcgttgt ttttgaggga ttggagtttg 2116021 acggcttttt ggaaccgctg tttccgttct taggtgaact gcttcctttt attttgagca 2116081 cctgtttagg ataaagtgta tctgatgtta agccatttaa ggtttttaat tcggctacag 2116141 tcatatttaa gctgtttgcg attttccaca gtgagtcacc aagcttgacc gtatatgtac 2116201 tttttgaaga acctgaagaa ttggaaccgc tgtttttctt tgatccattt gatccgcttg 2116261 aactgcttgt ccctttgatc ttaagctttt gccccggacg aatcaggtca ctgctcaggc 2116321 tgtttaagct tttaagctca gaaacactca ttttatgatt tttagcaatc atccataggg 2116381 aatcaccata tgcaactgtg tatgttgatg ttttgcttga attagatggg gatgtcgtgc 2116441 tttttttgct gctttcagga accttaagac tttgtccgac ataaagcacc gttgatttca 2116501 atttgttttc ggatttcaga gctgatattg tcgtatcata ctggcgggaa agtttccaaa 2116561 gagagtcacc gctttttact tttatcgttt ttgcttccgc gggtgctgcg gccatcgacg 2116621 acccaacaac tgcagaaaca gccaagccgg ctacaatctt ctttttcatt cattcaacct 2116681 cctaaactgt ttttttgcaa aaacagctag tattttgttt ccaaaaatgg cacacaactg 2116741 ttttatcgtc aatttttcag caagttaaac ccttttcaaa catttggcgc agcattttca 2116801 gcatcgttcg acctttaaac cttcaaataa acatctaaca ttttacataa gcacgatatg 2116861 tttttcgaaa gtctaaggaa ctatttaagc gagggtaaaa atgatggttt tctattgatg 2116921 aacgaagcag tttctcctcc tttcttgtct atttttctaa tcaattctct atcggcgtgt 2116981 caaatccctt cctctgcatt cttatgaaat ggcaaaaagc ctgttctttc gataagaaca 2117041 ggcttttaca ctatgcattt gctgattgag ttttttgttt tacagcttca agaatgctgt 2117101 cggctgcttt tttagagccg cctgccgctt tcagtgattg tccaatttct tttgcctttt 2117161 cagcatacga acgattattc attacttctt gtatcgtctc tttcagtagg ctttcagaca 2117221 attcttcctt tttaattact tttcctgcgc cgactttttc tacctgatct gcgacaacaa 2117281 attggtcgcc tcccatcgga atgacaacga gcggggtttc aaaatacaaa ccttcacttg 2117341 tgctgttcat tccgccgtgg gtcacaaata agctggctct tttcaagatc tcaagctgag 2117401 ggacatacgg gcgtacaatg aaattctccg gaatgtcgtt taactcactt gttttaatat 2117461 gcttgccgat ggaaagcaca actttaccgt caaagtcctt acacacttca aggcattgat 2117521 taaaaaactg cttttgatta ttaaaaatgg ttcccattga aataaacagc acgttttcat 2117581 tgtcaatctg atcaaatggg aaatcattgt ttccggctct ttctgtaatg gaaggaccga 2117641 caaatacata tcgctcgcca aattgctcag ccagtggctg aaatcccctt gatgtaaaga 2117701 cgattgtcaa gtcaccatca gctaaaaaaa catcaaatgg cttcttgatc tctgcttgaa 2117761 aatcagcatt taacgtttct gcaagctgct ggtatgattc ataatgaggc gaatcttcaa 2117821 gtgatccttt catgtacgct cccatcattt ccttcgcaaa ttcctcattc atcgcaaagg 2117881 ttgtacacaa tgaaaatctt ggcagcttca gcatgttggc aatgacttta cccgcgagaa 2117941 gatggtgatc atatatgaca taatcatacg attcatgttt gacttcctca taaatatgag 2118001 tcgcgatatc cttacaggct ttcaaaaaag cgcagagcat ttctgtgaaa tctctttctt 2118061 catcgccggt tgcgtttttc ccgaagtaat ctcctctgaa atcatgatac tcacgaaact 2118121 ctatatcaag agctgtgatt ttttctttat attccttcac tgcgtagtac gtaatgtttt 2118181 ctccccggga tttcagctcc ttcatcacac cgatagaggg attaatatgc ccttcaccgg 2118241 ggaaaccgat cattaataca ttagccatgc ggcagcaccc ttcctttgag aatttatgta 2118301 atattttata cggtactata aatgcataaa caggtaaagt atttcactta attaatattc 2118361 atcatatata acttttctac cagtttatat tccctgtctt caagacaaaa agcattcagc 2118421 ttgaagcgaa tgctttaata aagatgcgaa ttcagtcatt ttgtctcatg ataggattct 2118481 taatcaggcc ctttttatta tttttacgtt cttggtgaaa ttaacggata taatacaccg 2118541 tctttggcaa acgacatctt ccctgtttcc tctgaaacca cgagcaccag tgcatccgta 2118601 tagcccgaca taccaagagc cgcccggtgc cgggttccca aatggatatc cacttccttc 2118661 gtcgtcagcg ggagcacatt ggctgctgac acgagtttgt tttccctcac taataaagcg 2118721 ccgtcatgaa gagggtttcc gggaaaaaag atgctttcaa ttaatgaaga gctgatctcg 2118781 gcgtgtaggg aggtgccttt ttgaataaaa cgttcaaccg ggtctgctct ttcaatcaca 2118841 attaaagctc catgcttatg ttccgataag gctttaatcg ccttggccag ctcaataaat 2118901 gccggcgtaa attcctcaat gtatgattgc aaataaaagg aggatgcaat cccctgcatg 2118961 tcctgaaaaa cgtgccccaa atcatctaat tcacaaagga gacactggtc tttttcgtga 2119021 agcgttttca agattagaga tgcatcacct aatatttgct ctaagtacac ctgtattttc 2119081 cccttgaacg cattttctga tatctgctca tagcgcatag ccttcatctc ctgtttaaat 2119141 ttccaacttt tcacgaatgc ttatcttatt gatgcacatt ctattggtaa aggagggatg 2119201 taaagaatgg aaatcgaaag aatcattcag tatatttgca cctttttagg cgtgatttcg 2119261 ctttctttta tttatgccca aatgtttaga aaaacgaaac cgacaaaaaa agaataggcc 2119321 cggcgttcat tgctttttat acataaaatg ttataatttc tctcgttatg aaaaagaaac 2119381 ggagatcaat gtatgaaaga aactcaaaac gcccgggaaa aaatcaaaca gctcttgcac 2119441 attttaatac cgatattcat tacccaagcg gggctttctc tgatcacttt tctagatact 2119501 gtgatgtcag ggaaagtcag ccccgctgat ttagctggtg tcgccattgg ctcaagcctt 2119561 tggacccctg tttacacagg acttgcaggt atattaatgg cggtcacccc gattgtcgct 2119621 cagttattag gtgcagagaa aaaacagaag attcccttta ctgttttaca agctgtatac 2119681 gtggccgcgc ttcttagcat cgccgtttta gtgattggat atgctgcagt tgaccttatt 2119741 cttggccgat tgaaccttga tattcacgtg catcagattg ctaaacactt tttaggcttt 2119801 ttatcactgg gaattttccc tttatttgtt tacaccgtgt tgagatcatt catcgactca 2119861 ttaggaaaaa cgagagtcac catgatgatt acactcagtt ctcttccaat caattttgta 2119921 ttgaattatg tatttatctt cgggaagttc ggaatgccgg cacttggagg tgtaggcgcg 2119981 ggactggcat ccgcgttaac ttactggtgt atatgcatca tcagtttttt cattattcat 2120041 aaaaacgcac cgttttctga atacgggatt tttcttacca tgtataagtt ctcttggaaa 2120101 gcatgcaaaa atttgctcaa aatcgggctg cctattgggt tcgccgtgtt ttttgaaacg 2120161 agcattttcg cagctgtcac gcttctcatg agccattttc atacagtgac catcgcgtcc 2120221 caccaggcag ccatgaattt tgcgtctctt ttatatatgc tgccgcttag cgtgtccatg 2120281 gctctaacaa ttgttgtcgg atttgaagcg ggtgcagccc gttttaagga tgcacgctca 2120341 tatagcttaa tcggcatcat gatggcgatc ggcttttctt tgttcactgc cgcctgtatc 2120401 cttttattca gagagcaaat tgcgggcatg tacacttctg accccgatgt gctccggctg 2120461 acacagcact ttttaattta tgcgctattt tttcagcttt ccgatgctgt tgccgcaccg 2120521 atccagggag cactcagagg gtacaaagat gtgaactata cgcttgcggc cgcttttgtc 2120581 tcttactggg tcattggcct tccggtcggt tatatggtcg gtacgtttac aagcctcggt 2120641 gcattcggct attggattgg attaatagcg ggactcgccg ccggagcagt tgggctgttt 2120701 ttcaggctgg caaaactgca aaaacgttat tcgcaaaaac aacacattta aaagaggtga 2120761 tcaatcatgg caaaaaacaa aaaattattc gagtatcttt cccagcatgc ggaaaccatc 2120821 agttcaacat ggtatgaaac aatcgaggag actgatccca attccattta tgcctcaaca 2120881 gaccctgttg tcattcacaa tttaaagagc cagaatcttg cctttaacta taaaataaac 2120941 cgtattttta tagatgatga ggacgtatac ttgcctatac tgaaagaatg ggcctttgaa 2121001 gtcacacagg atcaagagca tttaaaaact cctatccact atattattcg ggagtttgtc 2121061 agagtgagag atttatatgt ttcttatgtg aaagaatttg tccatctcaa tcagaatact 2121121 gtgaaaagcg aagaagccga agacctgtat cacgccctta taaaagcgtt tgatcttgtg 2121181 attcatattt ttatagaaga aatgtacaaa aacacaagcc ttcagcttca ggcccaaaaa 2121241 gatatgatta ctgaattgag cgctccggtc atcgtgctgt ttcacagcgt cggactgctg 2121301 cctttaatcg gagatattga tacagtccgc gccaagctga ttatggaaaa cacactgcat 2121361 caatgtgcga aaaaaaaggt gacacaactg tatattgatt tgtcaggagt agctgtgatt 2121421 gatacgatgg ttgcccatca gctgttcagt ctgattgagg cgcttcgttt aatcggtgtt 2121481 tcttcaactt tgtctggaat ccgtccggaa atcgcgcaaa cagcggttca gctaggtttg 2121541 tctttcgaag gtatttcctt gagatccact ctcgcttcag ctattgcatc ggacttaaaa 2121601 ttaaaaaagg tataaggctt aaggccttat acctttttga ttaatcattc cattgatacg 2121661 tccaatatat ttcttcttca aaccatgttg ccataacagg ttcattattt ttcaatttct 2121721 cttcaagctc tctgagcatg ccttctgttt gtgtgcggtg agctcttaac gcattcattt 2121781 taatatcagc tacttctttg atatcaagta cgacatcagc ttcgccgaga acctcttctc 2121841 tgttgcgggt aatggccatg cagattgtac gcggacggtc ttctttcttt ttgcggtata 2121901 atgcacggat aaccgcttcc ccgcatgcat catggtcagg gtgcacaccg tgtccgggat 2121961 aaaatgtgac aattaaactt ggttttacat catctatgat ctcttccatg atatcagcta 2122021 aatactcatc gtcttcaaat tcgagcgttt tgtcacggag tccaagcatc cgaaggtcat 2122081 tgatatccat ttctttgcaa gcgttgatga gctcttgttt tcttagcagc ggcaacgttt 2122141 cccgattcgc gaaaaatgga tcgcccatat ttctgcccat ttcacctaaa gtggcgcagg 2122201 catacgtaac gggaatgtct ttttttctgt ttaaggcaat gaggcctgcc actccatatg 2122261 attcatcatc agggtgaggc aggattacta gtacatgttc tttcattatt attcaccctt 2122321 ttctttaaac tgtgaacggt ttttcgctga tttgcagaga aatagccagt ttaccgcccg 2122381 gcaggtgtcc cgccattaat aaacggtttt cttcatctac cgtgtattca gtcaagcctt 2122441 cagcataaat ccagccttct tctgttttca agccaacgcg gtaaggcccg ttgcctttga 2122501 tttttgcctg atgataagtg acttttgcat tgcgaatata cgcaacaacc gtcatgttct 2122561 tttcatttaa gtgcgctgaa taagaacctg tggtggtttc taaatggata tatacagggc 2122621 ggtccgcata tcgttctaaa gatgcttgca catcttcttt tatgatcgct ttcatgattg 2122681 ctcccctctt tcttctttta aatactctgc acgttctgta tgtaatttga ccagctgata 2122741 tttcacagcc ggttcgagct gtgaattcac aatgcgctga atcgcggcaa aatatttttc 2122801 cagcatcggt tttcggagtc ttggatgtgt tcgtttatcc aagagctcaa gatcaatcgc 2122861 ctctgctacc gcttctgcgt catcatgtgc gagagatcgg ttattccaaa gtgaagcata 2122921 ggctttcact atctctttat cattgtccat cgtcttgctc ctttatgtct tacatacatg 2122981 aaatgattat acataatata tgcatcagct gaaaagccaa aggcctcaat ggctttttga 2123041 cgcccgtttc cacttcactt gtgaaaacgt aaacaagagc agcgcagccc atatacagct 2123101 gaatgtaaaa gccttcgagc ttgaaaatgg ctcatggtaa acaaacagcc cgatcagcag 2123161 ggtaatggtc ggcgcaatat attgtaagat accgacttga tacagtggca gccgtttcgc 2123221 tccttccgca aacaataaga gcggcaaagc cgtaaacaca ccggccaaaa agagaagcag 2123281 ccacgtccct ccgctttctg cacccgctgg ctgaacatgt ccgctgaaca gcaaataccc 2123341 caatgcaatg ggcataatca tgaatgtttc cagcgttaaa ccgatggcgc tcggcaggct 2123401 tgttcttttt ttgcttaacc cgtacagccc aaagctgaat gcgagcagaa gcgcaacata 2123461 aggaatggag ccgtattgga acgccgagat gatgacaccg gctgccgcaa tcgaaacggc 2123521 cactaattgc aggcgattca gtttttcctt taaaaataaa atcccaagga gcactgatac 2123581 aagcggatta atgtaatagc caagactagc ctcaagcaaa aagccatggt tgacagccca 2123641 tatgtataca aaccagttga tcgaaatcag gatagaagca agaaataaag agaggatccc 2123701 tccgttcttt ttcagagagc gcaactcctg ccatcctatt ttccattgcc gcaagaaaaa 2123761 aagtacgata cacataaaaa caaaagacca tataatacga tgagccaaaa tatcaagagc 2123821 cggcagctgt tcgagaagct tccaatagag cggaaacagg ccccacatga taaatgaaac 2123881 ggctgtgtaa ataacgcctt tttttgtttc tgcatgttgc attgatatcc ctgcctttct 2123941 ttagagcatc ttatattata tcacgtgaaa gatctggtgg gcatatacta ttttgtccgt 2124001 gaagaaagga tgtgaagaca atgtttgagt ggaacaagta ctttcctttc cacaatcaat 2124061 tttctaaaga agcattaaaa aaagctgatc cgaaagaagt tgaaacgtat gtcaatcgtg 2124121 tgatggaaag tgtgttcggc agtgattatg cggctcaatt tcctttccgc gatcctctcc 2124181 cccaaaaaga acatcccgcc aaacctgatg caaaacctga tgtcaaacct gatattgata 2124241 tattcgaaac agcagaccat gtgtttgtaa aggtgccaat cagcgaagaa tggctggaac 2124301 aagtgagaat caaacacaca tctcacgaat tatggttgga aaacctccca agagcagatc 2124361 atccgaaaaa agtaaacctt ccttgtttag tcaaacgcaa aggaacaaaa gccgtctata 2124421 aggatggcct tctggaagtc atgtttcaaa agcagcaaga ctacaatatg tccgaggtag 2124481 aaatcatccg ataaaaaacg gcctgcaatc gatgcaggcc gttttttatt aatagaagcc 2124541 gggatatccc ccgtatggca cgccggcacc aaaaccgtac ggtccgcctc catatccata 2124601 agggccagga ggataggcat agggacgaga atagttaaac agcgcactcc cgagaaaacc 2124661 gcctaataaa ccgccgacta gaggagcgcc aaacaaaaaa ggactacgcg ccggatatcc 2124721 ggctggacct gggattccgc gtaaatacga atgatgaggg tacatgattt tttcctcctt 2124781 tatgtctgcc tatacgtaaa gtattcagca aggaagaaaa acgattgggc tacggactgt 2124841 ctatgattgt tacatcacaa gccctgccaa taacacacag ccgagccctg taaccgaaag 2124901 aactgttgta agcagcgtcc aggtttgaaa tgtttctttc atgctcaagc cgaaaaattc 2124961 ctttaccatc caaaatcctg catcatttac atgacacgca atgacactgc cggctcctgt 2125021 tgcaagcacc attaacgcag ggtttacact gccagcctcc ataagcggag ctgccattcc 2125081 cgctgtggta agcgcagcca cggtagcaga gcctagacac agacgcagaa ccgcggcgat 2125141 ggtccatgca acgaatagcg gcgacatgtt tgtttgacgg aaaaaatcag cgacataatc 2125201 gccgactccg ccgtcaatca gcacctgttt aaacgctcct ccccctccta tgatgagcag 2125261 catcatcgca atttgcgaaa ttgattctga aatagatctg ccgatttcct gcatagatat 2125321 tttacgggca tatcccatcg tatagagtgc aagcaacagc gaaatgagca ttgccgttcc 2125381 cggagtgccg ataaattcta taatgtcttt tccttttgaa tgttcactca ataataaaga 2125441 aaaaattgtt gccattgcca taaagataac cgggaataaa gacgtgacag cactgatcgc 2125501 aaagcccggt gtttcatcca gctgaaattc tttccttggt cctaaccccg ataggtttcc 2125561 atgcttttga tacgcaccag gaaaccgttt catcgcaaat ttattaaata aaggcccggc 2125621 aatcacagtt gtcggaacag cgatgatgat tccaaaaagc agcacctggc caatatgggc 2125681 accatatgca actgagatag cagttggagc aggatgcggg ggcaaaaatc cgtgagtaac 2125741 atttaaggcg gcggccatcg ggattcccag atacagaaaa ggcattttta attctttagc 2125801 aatcgcgtaa acaatcggta tcaacagaac aagaccgact tcaaaaaata gggcaatccc 2125861 gatgataaaa gaggcaacca caaccgccgc ctgtattcgt ttcctcccga atttgtcaat 2125921 cagcgtaatg gcgatccggt agccgccccc agcatctgag acaagcctcc caagcatcgc 2125981 gccaagtcca aacactaaag ctaaatgccc cagctgcccg ccaattccag tctcaattga 2126041 aagaacaatt ttattgatat ccattccaag tccgatggct actaaaaatg aaacgacaat 2126101 cagtgagaca aaggtattta attttacttt aataatgaga aataacagaa tcagcactcc 2126161 gacagctaca attaaaatcg gcatggtacc cctccaaaag tgttttatat gattctcgcg 2126221 acaatgtttt ggcgcttttc atgcctagat gaacagaaag cgctttcatt aataactaaa 2126281 aacgtcttgg ttatatgatt gttatctttt gatcaactaa tatgttcata ctaatctcct 2126341 aatcaatgac tgtcaatcgt ttttatgagc ttgtctcgat tacctaccgc ctaacccaat 2126401 gatttattag ttatatgttg attaactttt ggttatatgt tatgtttttt aaagttgact 2126461 gccaatcatt atatctctcc attgtctgga agcaaatgag acaatatgag aacagacgga 2126521 taacaacttc ataagaggag gagtacacat gccattattg cgttttgatg taattgaggg 2126581 ccgtgatgaa aaatcgctgc aattgttatt agatactgct caccaagcga tggttgaagc 2126641 atttggtgtt ccggaaagag accgttatca aattgtccat cagcatcccg caaacgagct 2126701 tataatccag gatgcgggat tagggtttca gagaaccaag gatatggtca tcattagcat 2126761 gacaagcaaa gcaagaaccg aaagccaaaa ggaaaaattg tatgctctgc ttgctgaaag 2126821 gctagaaaaa aaatgcgaaa tttcccctga cgacctcatg gtatctatta ctgagaatgg 2126881 tgacgcagac tggagtttcg gtctcggtga ggcgcaattt ttgaatggaa aactataaga 2126941 tttcgtctcc ccacaaaaaa aagaagagag agctccaaag aagctctctc ttttttcata 2127001 aatgcggaag tcatcagtat agaagcatcc agcaatacga aaaacctgga tctcctttta 2127061 tatccggttt aaatgccaat tggaagctga ctgggttttg gctgaaaata taaaattttg 2127121 ctgatttgca taataagata catcataatc cccatttaca ataggttgga tgttatagct 2127181 tattgatcat ttcctatttt atatatcccc ttcatatgca catgacattt ttgccaatcc 2127241 ggaaatatca gtctgacaaa tataaaaagt catgtaaacg ggtgtgaacc gtacttacat 2127301 gactcaccat ggaaacaaag gctctttttc aggtgccgct ttccttattt ctcttcttca 2127361 cacactgtgt caccaggctc gcaaaattga tcggcccatg cctgcatttc ttgaaataca 2127421 gcttgaagcg ctgttccttt ttcagtcagc gtgtagatga ctttgaccgg cgtttcaggg 2127481 agaacctgcc gttcgacaat ctcgttttgt tcaagctcct tcaagcgctc tgccaacatt 2127541 ttttggctga tcatcggtat tgtttccgtt atctctttaa accgtttcgg cccatccatt 2127601 agcacatgga tgatcagacc gttccatcgt tttcccagca atgagaatgc ggattccatt 2127661 ttagggcaca tcgtatttcc cataagtctt catcccttca tctattgatt gacatgtatt 2127721 caatgatcca ttacaataat ctttcaagtt acatttagta agcttctaac ttttctatta 2127781 tcataccacg tttatccgaa ggaggaaaca ctatgacgaa tactctggat gttttaaaag 2127841 cacgtgcatc tgtaaaggaa tatgatacaa atgccccgat ctctaaggag gagctgactg 2127901 agctattaga ccttgccact aaagcgcctt ctgcttggaa ccttcagcat tggcatttta 2127961 cagtattcca cagcgatgaa tcaaaagcgg agcttcttcc tgtagcgtat aatcaaaaac 2128021 aaatcgttga gtcttctgct gttgttgcca ttttaggcga tttaaaggca aatgaaaacg 2128081 gtgaagaagt ttatgctgaa ttagcaagcc aaggctatat tacggatgaa atcaaacaaa 2128141 cattgctcgg ccaaatcaac ggtgcttacc aaagcgagca attcgcacgt gattccgctt 2128201 tcttaaatgc ttctttagct gctatgcagc ttatgattgc cgcaaaagca aaaggttatg 2128261 acacttgcgc aatcggcgga tttaacaaag agcagttcca aaagcaattt gatatcagtg 2128321 agcgctatgt tccggttatg cttatttcaa tcggcaaagc agtgaagcct gcgcatcaaa 2128381 gcaaccgtct gccgctttca aaagtatcaa cttggctgta aggatatgaa aaaccttagt 2128441 ccgaaatccg gactaaggtt tttttataca atcgcctctt tgtaccattc acgagcctgt 2128501 tcagcttcat gctgagtcag ctgatggccc ccgtcctgcc agtaaacgga ggctgatgcc 2128561 ccgctgtcac gcaaatagcg gtaaagctct tctgattctt ccttcgtgca aagaggatcg 2128621 tatttcccgg caccgataaa aacagggagc cccgccatat caggcagctc gataccccga 2128681 atcggaacca ttggatgatg cagaatagcc ccttttaaca catctttata atgaaaaagc 2128741 aggcttgccg caatgtttgc gccgtttgaa taaccgactg caatcactcg gccgcgatta 2128801 aactgatgcg tttctgcagc ctcgtcgata aaatctttca attctcttgt ccgcaccaca 2128861 agatcctttt catcaaaaac tccttcactc agacgtttga aaaatcgcgg cattccattt 2128921 tcaagcaccg atcctctgac accaagcaaa tgggcatcag ggtctataaa ccgccccaat 2128981 gaaagcagat cgtgttcatt accacccgtg ccatgcaaca gcaaaagtac gttgtcagat 2129041 gttcctttct cataaatatg cttcattata aattccccct tttaaagttc aggtaaaatg 2129101 tctgtaattt gttgtctatg tttctccagc cattcaggca gttttaagga agtccctagc 2129161 tcagcaaacg tttcatctgt cataaagccc ggttcatctg tggcaatttc aaataagata 2129221 ccgcctttct ccctaaaata aactgatgta aagtattccc tgtcgagaat ttctgacgaa 2129281 ggcagatggt tttcagcaat aatcggcagc catttcgcct gttccttttt cttagtccga 2129341 aacgctacat ggtgtaccgt accatatcct ccgactcctc ttttttcagg atgtaaatgg 2129401 acatcaatga caccgccgac cgccgctgaa gatgccagtc tgacaatctg gtcttcttcg 2129461 gccactttgg tgtatccaaa gctttccgtt aacaattgta tggtcgcctg cgggtcgtag 2129521 gaatatagca gcacaccttt cattcccgta attgcttcat ttgttgtgat cccgtcaggc 2129581 gtccactcgc ttttgccgct tttcgcatcc tccatgatcg ccagcggaag gtcttctgta 2129641 tcatcaaaaa taagaccttt ttcaccaaac aacgtttttt cctctaggct cagcccgctt 2129701 ttctcaagac gttccttcca aaaagacagg gagcctgagg gaactgaaaa gtacacccgg 2129761 cccgcttggc cttttcctac cgttccctgt ccgcttcctt ggaacggaaa aaaggtcatt 2129821 attgtaccgg gatctccgtt ttgattccca aagtaaaaat gatacgttcc gggatcatca 2129881 aagtttactg tttttttaac gagcctgagc ccaagcactt ctgtataaaa tcgcaagttt 2129941 tcttgcggat ctctggcgaa tgctgtgaca tggtgcaatc cttctgtttt cattttctca 2130001 ctcctattta tctcgatttc aagatattta ttattttaaa cctttattga aaaggatgca 2130061 aaccatgtgt tttgattaaa taattgaaaa aatcattttt ttctaataat tatcttgtga 2130121 tcttttctta caactgctat tatagtgagc attatcatgt ttcaggagga aagtaaatgg 2130181 ttaaaaaagc acttattgtt attctcattc ttttgccatt cgttcagctc gcgcttttgc 2130241 cgcttgtgaa tcgaatagaa ccgattatgt tcggcctgcc gtttttccac ttttggctgc 2130301 tgctgtggat tattgttacg ccgttatgct cgtttggcat ttatcagatg caaaaaaaag 2130361 atggaggact tgaataatgc aagggaatct gactgcactt ctcattactg ctattattgt 2130421 tttaaccgtt gtctgtatcg gctttctcgc cggaagagac aaatcctcac gtacttctgt 2130481 ggaagaatgg tctgtcggcg gcagacgctt cggcggtctt ctcgtctggt ttttagtagg 2130541 cgctgacctt tatacggcct atactttctt agggttgacc agtactgctt ttacaggcgg 2130601 aagtgttgca tttttcgcca ttccttattc tgtgttggcc tactttatcg cctacttctt 2130661 cttgccaaaa ctttggaaag ttgcgaaaat tcataaatta acaacactcg cggattatgc 2130721 ccgggaacgt tttaacagta agcttttggc aagcctcgtt gccatcgttg gggtactcat 2130781 gcttattccg tacatatgcc ttcagctgag cggcattcaa gacacgcttc aggttgccgg 2130841 cactggctat attaacgtaa aattcgttgt gatcatttca tttattcttg ttgctcttta 2130901 cacattcttc agcgggatta aagggcccac atatacagcc atcattaagg acattttagt 2130961 atgggtcatt atgctgttta tggtggtgtc cctccctctc attcatttta acggctggac 2131021 gccaatgatt gacacgttag tgaaggaagc gccgcaaatg ctgacgatac cgtcagaagg 2131081 gccaaaaggc attccttggt ttatcacagc atctattgtt tccgctctgg cactttttat 2131141 gtgggcacat gccgctacag gtgttttcac ggcgaaaagc gctgatgcag taagaaaaaa 2131201 cagcatgttt ttgccgcttt ataatatcgt gttaattttg gttatttttc ttggctttat 2131261 cgcctttctt gttctgccgg aagatacaaa tccaaggctg gcgctgctgc atttgattca 2131321 aacatcttac ggcggcgtgg cacaaggctt tgcatatgcc actatcgctc ttgcttcatt 2131381 aataccttgt tccattatgg caatcggcgc atcgaattta ttcgccaaca acctataccg 2131441 ggatttgatt catccgaatg tgtcgcaaag caagctgact cttgtcacac gttcaatggt 2131501 gtttgttgtc atcggtcttg cgctgctgtt tggaatgctg ttcccgactg ccttagtgac 2131561 acttcagcta ttaggtgtat ccggtatggt gcaaatcttc cctgcgattg ctgtcagcct 2131621 gttctggaaa aaccaaacga aagaagcaac ggttatcgga ttattagccg gcctagcggt 2131681 aacgtttatt gtgtatatca ctcaatccgc acatggcatt tatgaaggat tctggggatt 2131741 ggccgccaac atgatcgctg tggtcatcct gaatccgctg ttcgttaaaa acgcgggatc 2131801 caatcctgtc attgaaggtt tatttggcaa aaaacaagac gctaatccaa atcaaaaggg 2131861 cgcataaaaa aaccatacgc ggcagccgcg tatggttttt tttacatttc ttttttcagt 2131921 gtttcaattg ccttttccat ttgcgtatca ttatcagaca gcttcttttg aagttctatc 2131981 attaatttcg ttgttgtatc gccagtcagt atgcctgttt cattcagctt ctcttttttc 2132041 tggaactgtt tgacgacaga tacaaaatcc tggtcataca tactgttaac ctttaccttg 2132101 taaccaagtg ctttgagcat tttctgagcc actttgacgt ttgtgcctgt atcacctgat 2132161 ttgtacgttt tatctgcgtc caaatacggc agcttcgcgt aatcaggcag ctctgctttc 2132221 acttgaggct tgatgccttt tttgtgaatc cattcgccat cagcagtcag ccatttggca 2132281 actgtcagtt tgacggtaga gccatcatca tattcttttg ccgtttgtac tgtacctttg 2132341 ccgaatgtcg tctcgccgat taacggtacg tttgacgatt catgaagggc agcggccata 2132401 atttcggctg cgcttgctgt accgtcattt actaaaacga cggtcggctt ggtcactttc 2132461 cgttcttttt cggccttcat gacttctttt gaaccgtttt tgtattcaac ctgcatgatg 2132521 tttttccctt tatcaatgaa caggttgctc atcgtaatcg cctgttccat taagccgccc 2132581 gggttgcctc tcaagtctaa aatatagcct ttggcgcctt ttttctctaa actgtcaatc 2132641 gcatctgtca gctctttagc tgttgtttca gagaaagaag tgatttgaat ttctccgatg 2132701 ttgttgtctt tcatctctga atagacagtc tctacaggaa tggtatcgcg cttaatggaa 2132761 agatcgatat tccccactcc cgctctgttc agttcaagct tcacctttgt gccctttttg 2132821 cctcggatta aagcgacggc ttcatttaca ttcatgcctt ttacgctttt tccatttacc 2132881 ttaatgattt ggtccctcgg tttgataccg gctttttcag caggtgaacc tttaattggg 2132941 gatacaataa ggatttctcc gtctttctcc tctacttggg ctccgattcc ttcaaaagat 2133001 gctgaaatcg tctcgtcgaa tgatttcgct tgctcttgat ccatatatgt agaatacgga 2133061 tcatccagtg attgaatcat tcctttaatt gctccgtcta ctaatttgtc atcatctgtt 2133121 ttttggtaat aatcactttt gatttgctca tacgctttat ttaatttgtc gaacttgctg 2133181 tctcctgtgc ttgctgattt ttggcccagg atactggaat tgcccgtaat aaataaagta 2133241 agcgccgaag cgacaactgc agtgatcagc acaataaaaa acagttttaa ttgccgtttc 2133301 aattaaacac cacctttttc ttcttacatt attatcatgg acgaattctt attcgtcaac 2133361 tcggagcaga aatgaaagag aaacgccctt cttttgcttt tcataaacct atgtctttat 2133421 acgacatatg ataaggaaaa aggaggattc gatattgagc cgatatttag aaatgctgtc 2133481 cttattcggt gtcgcagggg cgcacccagg cgggctggct ttttcaaaag cggtcttgca 2133541 aaaggctgca ccctctccgg atcagccgat tcttgatgcc ggatgcggaa cagggcaaac 2133601 ggcggcttat ttaggacatt tgctgtatcc tgtaacagtc gttgataaag atcctattat 2133661 gcttgagaaa gcgaaaaaaa gatttgcgaa tgaagggctt gccatccctg catatcaggc 2133721 ggagctggaa catctcccgt tttcttctga gtccttttcc tgcgtcctgt cagaatcggt 2133781 cctcagtttt tcacgcctga catcctctct tcaagaaatt tcaagagttt taaaacccag 2133841 cgggatgctg attggtatcg aagctgcttt aaaaaaacca atgccccctg cagaaaagaa 2133901 gcaaatgatg gatttttacg gatttacttg cttacatgaa gaaagcgaat ggcataaact 2133961 cctaagatcc tatggctttc aaaaaacaga agcgatgtca cttcttccgg aagacatgga 2134021 atttgaacca accacagaaa tggatttatc gcaaacgatt gatcccatct attacgatac 2134081 gcttcaaaca cattatcagc tcatgcagtt atatagtgag tacatgggtc attgtatttt 2134141 tatcgcgtac aagtaaaacg gcgtatcgcc ccctgttttc gtccaacctt tttttcctat 2134201 ctatcatatg ctgatagaaa gtcaggatag gaggggaaca atattggaga gatattatca 2134261 tctttgcaaa aaccatcaag gtaaagtcgt cagaattaca gagagaggcg ggagagttca 2134321 cgtcggcaga attacccgtg taacaagaga cagagttttt atagctccgg tcggcggagg 2134381 gccaagaggt ttcggttacg gatattgggg cggttattgg ggatatggag cggcttacgg 2134441 gatttccctc ggtttaattg caggagtggc tctggctggt ttattcttct ggtaagcata 2134501 gaacaaatgc tagattcacc agacacaatg aagcccgctt atctagtgta agcgggcttt 2134561 tcattttaaa ttttcttcac tttttcaaag tactcttcaa gcgttaaatc attatcttgg 2134621 atgacctttg cggctttttt gcctacatag cgcagatgcc atggctcata ttcatatttc 2134681 gtgatatctt ctttattttt cggatagcga ataataaagc catatttata agcattgtcc 2134741 tgcacccatt tcccgtctgc cgtgcttccg aacgcttcat ttagctcaaa gccattgctc 2134801 cggctcgaaa tgtccatcgc aaggcctgtt tgatgctcgc tttcacccgg gtaagcgacc 2134861 gcttcctttg ccttcctttc cccttttagg cttacttcat tgtcaaaaat gactttctgt 2134921 ctgtcatacg aacggtaccc tgagacagct gccagttcat agccttcctt tttggcagca 2134981 tcgaacattg tttttaatgc gtcggccgct tcttttctga tgtaacgttt ttgaatcttt 2135041 tcttcaaaag aaaactctac atcaggtatg acaagatcgc taggttcata gtttccgggc 2135101 agtgcatatt gtttattgac aagcgcgagt atattttctg gattttgaat ggtttccaga 2135161 ccatcgactt ttttaatatc attgaaatac tggctttcca atgaaaactc actgttttga 2135221 gtgtttgatt ttttgctgtc agctgttttt tgttctgttt gctttgtttc tgctgtggtt 2135281 ttcgtatcct tttgagcatc tccgttcgac atgctgcagc cggctccgac tattgccgtt 2135341 acactcagag cggcagccag tgagaaccat ttaccggact ttttcatatt acattacctt 2135401 ccttttatca atcgtttccg catgcataaa gaagaggctg ccggcaccca gcacgcctct 2135461 tgatatattt tattgtgata cggaatgtaa agccacttct atcatatcat gaaatgtcgt 2135521 ttgacgctct tccgctgtcg tttcttctcc tgttaatacg tgatcactca cggtgagaat 2135581 tgacagggct tttcttccgt gcttcgctgc taatgtatac aatgcagttg tttccatttc 2135641 aacgccaagc acaccgtatt ttgcaagttt ttcaatttgc gaatcgtcat tgtagaactg 2135701 gtcagctgta aatacgcttc ctacagtcac cggcacacct ttatcctttg cggcatcata 2135761 ggcatttttt aaaagctcga aatctgcgca aggcgcaaaa tcaacgcttc cgaaagcaac 2135821 tctgttcatt tgtgaatcag ttgaggaggt catcgccaaa atgacgtctc gcactttgac 2135881 atctttacga atagcgccgc aggaaccgac tcttattaga ttttgcacat cgtagctttg 2135941 aattaattca ttcacataaa ttgaaataga cggaactccc attcccgtgc cttgtactga 2136001 gattttttta cctttatatg tacccgtaaa tccatacatg cctctgactt cattgtagca 2136061 ttctacattt tcaagatacg tttctgcaat aaattttgct ctgagaggat ctcccggcaa 2136121 aagcacagta tccgcaattt gtcctttttc agcacctata tgtacactca tctcatatcc 2136181 tcctgtaaat ctaaattatc atccagcccg tccattttac aacgaatgtc atgatgaaac 2136241 aaacttcagc attgattata aaggaatata tcgaaaaaag aaatgttcga ggatctgtta 2136301 ggcacttcct cagaaaaacg gataatcggg gtgttaattt gaaaacctaa ccgcaggaag 2136361 gaggggtggg acatgggtaa aaaacatcgt aaccggatca ccggccaaaa aaagaacaat 2136421 catatacctg aaaaagatat cattgcagct gaagaagcac acgggaaaga atattccgct 2136481 gccaaacgca agccttaaaa ctgcagaaaa ctgcgggttt ccgcagtttt cttttcatta 2136541 tgtcgtttgt acaatcagac gattgatttt cctccagccg gcgggaagca gttgataata 2136601 tgttttccct tttctgcctt catcaatcag gatcacgtcc cctgtggcca tgaatcttgc 2136661 atcataatca ctcggaacag tgtcgaatac attaaacaaa gagaatgctc ttttcagcac 2136721 gtcttgatga tcgctcccgt tcagttcagt tcgatagacg gctctgtagc cctttttttc 2136781 gccaaaccgg ggtgtctgaa atattgtcac gtcataggaa caagacttct ttttaaacac 2136841 ggataacatc atcaagatcc cctccctttt atttctttaa catattggcg tttttgctgt 2136901 gttttcctct ctctattttt gtcgaaaccg cttaatcttt tcgtcaaaac cttttactag 2136961 gaaaaacaga agcaagccga ggctaaagcc tcctaacacg tctgtcacaa aatgaacccc 2137021 cagatacact ctgcttatgc cgactaaaac agcaattaca ccggctatga tatataccat 2137081 ttttttatgc ttagacaaaa acgggagatg tttcactaaa aagtaagcaa taacaggata 2137141 gacacaagca gcattcatgg aatggccgct cggaaaactg aaggatgatt catgaaccag 2137201 cggtgcaaaa tcaggcctca ctctttcgat ccattctttt aagactttgt ttaacagccg 2137261 atctgtgccg aatactaaga gcatcaacag gccgtcccat gtttttctgt agaaaaacat 2137321 gcctgctcca atgatgacaa ttagagggag cagaaaagaa gaagcaccaa gatgcgtgat 2137381 ccccgtcatg acttcattaa gccatggctg acggatcaaa acagctgcct tgcttattgc 2137441 ttcatctgca gattgaacag catttgtatg aatggccgca gctagaatta aaaagaaaag 2137501 aaacaaacta acgggcttgt acaattttaa ccacctcaat tttcacagaa gtcatagaac 2137561 atgaataata aaaccggagc tgaccgctcc ggttttaagc ctcactcatc ttcatccagc 2137621 tcttcatcta tcatacattt ttctatcaaa taatcaaagg taatatcagc gatttcaaac 2137681 agctcatcct cactcggtat gtagccccgt cttgcaagct ctctgtaaaa aaattcagcg 2137741 atttcttccg tatcaatcac aagatctatt tctttcatct ccgtaccgcc tcctttttta 2137801 tgttttatga aaaaacaggc tgaattatac ccggtgttct aaacaattct ttcagtcata 2137861 tattgaataa aaaacgagcc atgggaggct gacgctatga ttgctaaaat gatggaagca 2137921 ctggacggag aaagatttga tatcataatg gaaaaaacgc tcaaaggaat gacgcgtgtg 2137981 atgatttggg gctgtctgcc atatttttta tatgtcttga tccgtatgtt cacaaattaa 2138041 ctgaaatgct cttttaaact ttccaaaaca aacatcatca tgtctttata ttcttcatcc 2138101 tgaaacattt cgtacagaat tttgtagtca ttataaatat ccagaagctc atcaacaatt 2138161 gacacagcaa ggatgtgaag ggtatcttga tcttcatcac cgccttcaaa ctgaagaaga 2138221 gcagacgatg cgatatcttc gccgatctca tggccagttt ctccgacata atggacaaac 2138281 aacagctgat gcacaaactg gtccatttca tattttctaa gcaccagcgt gagatcctct 2138341 tcctccgttt caagccactc tccatccttt aaacgggtca gctcataaat gatatcttcc 2138401 cagccatctt ctaaatatct ccaaatttct gttctatggc cgataatgcg aaagagttct 2138461 tttccataat ctttaacata aacaacgtcc ccaataagga attcatactc aatatcaagc 2138521 ttctccatgt cgacaatgac accctcataa tctttataaa gctgaataga tgattcaaag 2138581 tataaaactt cgttatgatt gacttcataa agatagtgtt tatcaatttg gtgtactttt 2138641 gtgatggtgc cgactgttcc atacataatg acgactacga tatcccctac ttggaatttc 2138701 ggtttatttt gcttcatggt gtctccccct cgccgcaaca tttctcatac gctatcgtat 2138761 gccgggtgaa gccaattcgc atgggcatga aaaccaaagg aaatatccaa ttatggtatg 2138821 ggtatggaca taaaaaaatc cgcagtgatc tgcggatgaa acagctatta tctgccgtgc 2138881 acttcagact cgtattgatc ccaagcttca tcaaacgtcg ccatcgtgtg aaggtaatca 2138941 gcattcagct ccaaatatga actgatttca tgataatcgg ttgatgtttt tggaaagctg 2139001 tgatcctcat acgcctgatt ggcaaattca ctgatgctgt ccttcggctt agggtgtctg 2139061 tatttcaata aatagtgata aaaggatttc atgggtttcc cctcctgatg tctgtctttt 2139121 gttgttctat tatacagttc aagtgtaaaa ttacaacaaa agaatactga aacatgactc 2139181 aggagaagtc aaaatagttg cgtttcaaaa ttctttctgt ctccatgagc tgctgatatg 2139241 tcaggctttc aggcagtttt tttgtttgaa ttaaaagcag ctgatcctca atctctttaa 2139301 ccgtgttttc ctcttgatag gtcataccgc aggaagaaca taccatggca ggggtgtctg 2139361 tcagttctat agccctcgtt ccatcaggga gctcccagta caccgtgttc ctgccgggca 2139421 ccgcttcgag ctcgccgcac cattcgcatg ttttcatgaa gaatcccctc cgcattcagt 2139481 ctctttctgt tttttctgct gcgccaaaaa tttcttttct ttgagctgat ctcttttctc 2139541 acgccgatct tttaatgttt catgctccgg atttgcgatg tatgcctctc tccttttgat 2139601 tctgtctaca ttttcaggtg taaacgaaac ttctttgtca gcaaaaatgg cactcagccc 2139661 gatcggctcc tttttgtcag cggtttcagg gaaaacggac tcaaaatagg cgtctgcctg 2139721 attggggata taattctctg gttccggata tgacgtaatc acaccttcaa aatttcttaa 2139781 gatcactttg tcaggacttt gtgacaggac atagtttggc tgcagggcga ttttacctcc 2139841 tccgcctggt gcgtcaacga caaaggtagg aaccgcatag cctgaggtat gacctctcag 2139901 cccttcaatg atctccaaac ctttggaaac aggagctctg aaatgcccta ttccttctga 2139961 cagatcacat tggtaaatat aataaggacg gactctgatt tttaccaagt catgcatgag 2140021 ctttttcata attggaaccg aatcattaat acctgctaat acgacagcct gatttccgac 2140081 cggcactccc gcgttcacca gcttttcaca tgcctcaacg gattcttctg tcatttcgat 2140141 gcttgtgtta aaatgggtgt tcagccagac cggatgatat tttttcaata tctcgcacag 2140201 atgatcggta atgcgctgcg gaaagacgac gggagctctt gttccgattc tgatgacttc 2140261 cagatgcgga atgctgcgca gctcttttaa aatatattct aaaatttggt cgttgatgag 2140321 cagcccatca ccgcctgaaa ttaaacaatc gcggatttcg ggtgtttccc ggatataagc 2140381 aattgcagca tcaagctgtt ttttggggac gcccattccg atttgtccgg aaaagcgcct 2140441 tcttgtgcag tagcggcagt acatggaaca ttgattcgtg acaagaaaca gcacacggtc 2140501 gggatagcgg tgtgtcagac cgggtaccgg tgaatcttca tcctcatgaa gcgggtcttc 2140561 cagatcgtat tttgttttgt gcatttcttc agaaagcggc acagactgca tgcgtaccgg 2140621 gcatctcgga ttgtcggggt ccattaaaga agcatagtaa ggtgtaatat ttaaggggat 2140681 cgttttggta gaaattctga cgccttcctc ttcatcctcg gtcagattaa tgactttctt 2140741 taaatcatct aacgttctta cagtgtgtgt cagctgccaa agccaatcgt tccatttctc 2140801 ttccggaacg tccttccata actcgatctc cttccaatgc cgtttcggtt tataccattt 2140861 gtttttcaaa cgaactcctc ctcgcgcata ttttgactta cagttgcttg caccaaatat 2140921 tcatgttttc aaggccttcg gctataaagc aattattgat cagccttccg ccatactgat 2140981 aacctgaatg gtacaacaca gcattcatcc caaaagacga agcacgggcg agagaaaaca 2141041 catgaacgat atcctctcca gccatttctt tttctaacgc ctcgattaaa aagcttgtta 2141101 acgaatggcc gcgatattcc ggcagcacag cgcaatcggt tatttctgca tgcccaagct 2141161 ctggattgat ttctgcgctt gctgcgctga tcaggcggtc atgatcaagc atgatataat 2141221 acaccgtatt tgcattcatc gtcttttcaa tataagcggg gtcaaatacc ggggttgggt 2141281 acgtgcggaa tactttttta tacagcatcg atagctggta catgtcgttt gtttctgctt 2141341 ttctcatcgt aaaaacgggt gtactgtcgt tgcgaagacg gggcgctgtg cgatatatgg 2141401 cttcgatgat ctcctgttcc tctgtataag aatctgtttg tctccggctt tctgaaaggt 2141461 aacgtaccat gacacaagcc gaatggccga gataatagcc ctttagatag ccctccggcg 2141521 caaataattg tttggcaagg atcggctcat catgctgctt cgcatagaca atgatttttt 2141581 ctgcattctc ttcttttgcc gctgccacga tatccggcag ggccttctca atggctccgt 2141641 cataacgaac cactctgatt cgtttattaa agccgtcatg gtccaaaact gctgtgacac 2141701 cgctactctt tattgacttg agcatccgca tcctccccat ctgtatgaag gccgcaccaa 2141761 tccatgacaa aaagtgcaat aattttagca gattctatca tggcttcaac ctcaatgtat 2141821 tcattggcct gatgagccgt ttttgtttcc cccggcccga aaacgatcac tggtgtatct 2141881 cctgcatggt acaaaagccc tccatccgtt ccccacgggg aagcctcaat aatcggctct 2141941 gtctgtttca ttttttgata ggctgattgc agcacagaaa ttaaagggtg atcatcaggt 2142001 aaatcattcg gcagccattg agcgccaaac cattcgactt gtacgggatg gcgtttaaac 2142061 cattcgtcat ggtattctaa atccttcagc cagttttcca attcaagttt tacagcttct 2142121 ggtttctcat ggggagcaat tccgcatctc ccttctatga cgacacggtc tgcaactgaa 2142181 gatggccagg caccgcctga gatggtgccg atattcaccg gtaccggtat tgggatattg 2142241 tcatacagcg gatctgaaat tctcgcattg cggactttct ccagctcttg tatcgctgtg 2142301 ataacgtgca tgcttttttc aatcgcgctt accccttcat agcgtgtgcc cccatgtgcg 2142361 gataatccct tcacagtgat ccgaaaccac atcgaaccct gctgcttaat aaatagtttc 2142421 atattcgtcg gttcaggaat cagcgccccg tcagcacgat agcctctcat gatggcggaa 2142481 agtgtaccgg cgccgccgca ctcttcatct acaacactct gaaacaatac atctcccttc 2142541 agtttgacat cgcaggcgtg cagggcttct aaagcaaaaa gaagggctgt attgcctccc 2142601 ttcatatccg ttgagccgcg gccgtatatt ttaccgtttt cttcgacagc ttgatacggt 2142661 tcatacttcc aatcctttac gcttccttca ggcacaacat cgatatggcc gttcaaaatc 2142721 agggacctgc ctccgccggc tcccgttttt ttagccacga tattcgggct ctcatgaaaa 2142781 tcggatcggt tagatttaaa gtagggatgc tgttttaatt gctttatgct tggctcccat 2142841 acatcaatgt ccatatgaaa ttgccgcagc ttttcaagca caacagcttg ggcgttaaac 2142901 tctgacccca atgtgctttt ttccccaatc agccttttga gaagacgaat ggctttggcc 2142961 gaatgctgat caagccactc gattactttt ctttcaatgt cttgcatcct cattccccct 2143021 cttaagaaaa aggcatatct attttgattt cagcttctgt cagcctcgtc acctcatcga 2143081 ttgtcgagcc attcatcagc tcttttaaaa tgaagtgatg gctatcgacc tcaagaaccg 2143141 ctttttcggt aataatcaaa tctacacagc ctgcagcagt taatggcagc gtacatcttt 2143201 ctgttaattt aggccttccc ttttgatctg tatgactcat gacgacaacc acttttttcg 2143261 ctttttgggc aagctccatc gccccgccca taccaggcac cttttttccc ggaacaagcc 2143321 aatttgccaa atctcctgat tggctcacct gcagggcgcc taaaatcgta atgtcaattt 2143381 tgccttttct gatcatcgca aaagacatgg ttgtatcaaa ataagaagcc ccttttacag 2143441 cgcggacagg atatcccgcg gcgttgcata aatgcgcatc ctcttctccc ttttcgggac 2143501 tttctccaat gccaaggaca ccgttttccg cttgaaacat gacctgcatg tcaggcttca 2143561 aaaagttcgg taccaaggaa gggataccga taccgagatt cacaatcatg ccctgcttaa 2143621 tttcagtagc agcgcgtttt gcaatctgtt ctctttctgc tactcccaag cccatttcca 2143681 cttcactccc tcgcttcgta caaccccctc aacaaaaacc cccggtgtga caatcatttc 2143741 ttcagaaatc tcccccatcg gaacgatacg ctcagcttcg gcaaaggttc tcctggcggc 2143801 cattgccata agcgggttca tattgcgcgc ggttttgtca tacgttagat tgccgaattc 2143861 atctgcaatg taagcattga tgaaagcaaa atcagcagtc agcgcctctt caatcaagta 2143921 tcgttttccc gccactgtta cgatgtcctt tttttcgcaa accatttgat tatcaatgcc 2143981 cacgtcggtt aaaataccgc caagccccgc tccgccggcg cgaatccgtt ccgcaagcgt 2144041 tccctgaggt gaaaattgaa cctctaacgt cccctctgtc atctgttttc cggctactgg 2144101 attggaaccg atatgcgagg cgatcagggt tttgacccgt tgattaacaa taagcgggcc 2144161 gattccgata tccgggaaac cggcgtcatt gcaaatcaca gtcaaatccg ttacaccgct 2144221 gtccaatatc gcttcaatca atgaaggagg cgacccgact cccccaaaac cgccaaacat 2144281 cagaaccgat ccatcccgaa catctgcaat tgctgtgtca atgctgattg ctttttgaaa 2144341 tggcgccatt taatgtcaat ccttttttaa gtttttttcg accgctgcaa ctgtttctga 2144401 aaaaatagag ataagctctt ccatttcacc gtctgaaata gtaaaaggag gagcaataat 2144461 gacagcatct ccttctccac tgtctattcc agctttggaa ggataaacaa tcagcccgcg 2144521 ttttttcgcc tcgctgacaa taagctgggt tatcgcctgc tctggcggaa acactttctt 2144581 cgttttttgg tctgccacaa attcaatgcc taatagcagt ccttttccgc gcacctcacc 2144641 tataatgccg ctttgagatg ccgcctcatc aagcttcttc ttcagcacag cgcccttttt 2144701 ttctgattgt ttgatcaagc cgtgctttaa cacatatcgc aaaacttcaa gagcagcttt 2144761 ggctgaatag ggatgtgcac tatatgtgtg accgctcata atcacacctg acccttgttt 2144821 tatggtttca ataatagaat cagatacgac ggcagcagca ataggtgcat accccgcacc 2144881 gagtcccttc cccagtacag caatatcagg tacggtatcc caatgctctg tcgcgagcat 2144941 ccttcctgtt ctcccaagcc ccgtcatcac ttcatctgca ataaaaagca catcgtgtgt 2145001 gcggcatacc tcacttaatc tctcataata tcccggaggc ggagtaatcg ctgctcctgc 2145061 agcaccaata ataggctcag ccacaaagcc ggcgatgaat tggcttccga ttcttttaat 2145121 catggtgtcc agttcatcag ctgcagtctg aacaaagtct tcttccgtct cgtgattcag 2145181 ccgataaata tgtggagctg agatagctgg ataccgctca atgagatggg tgaaccggta 2145241 tctcctttca taaaaaccag acaatgaaag cgctcccaaa gttattccgt ggtaactgct 2145301 ccatcgagac aaaaagatgg atttttgtgt ttgctttttt tcctgccaat actgaatggc 2145361 gattttcata gctgtttcta tcgcttctga tccgctgttg acaaaaaaag accaattcac 2145421 atctccgggc agctcctgtg ccaagagagc ggctaattgc tcggcgggct cactcgtaaa 2145481 ctgtgagcgg taagcaaaag acacctgatc aagctgttct ttcagcttct cagtcacatc 2145541 acgaactccg tggccgatat tacatgtcac cgcacctgac gagccgtcga gatatttttt 2145601 tccggtctga tcataaacat atgaaccctt cgcataactg acaaccggat aggccgagct 2145661 aagctctggc ttaatcaaat aactgctcat gctcccacct caaaacccct tttaccatat 2145721 tgtatgagtg tccaaatggc ggcatgacgt tccccgcaaa aactttttca cataaaaaga 2145781 gccttcctaa taaggaaggc tcttttgaaa tttcagcatc tagcaaataa aagcggctcc 2145841 aacaataatt aataaaatga acaagacaac aattaacaca aatgtatttg tcccgcagcc 2145901 aaatccgtaa ccgtacccag agtatccata catgctgttt tcatcctttc ttatcacgat 2145961 atacgacatt ttatgcgggc caagtcccaa atggtttgtg caaacgccta tttcatgtaa 2146021 ggaaataatg aaatacagta tgcacccgct catatttttt aaacgtcagc ttttcgtaaa 2146081 actgagttgc accgtcagtg cttgcagcca ctaagtaggc tgcttccatt cctagtgatt 2146141 tggcgatgga cagcatttct ttcactaaga tactgccgta gcccttcctt tgaaactgat 2146201 ctaaaattgc cacttcttcg attttagccg ttttctcttg atgatcgata aacagctcgc 2146261 cgcacccaat gggaactttc tgtgcctggt cgctgtaaca aacaacaaga atgattatat 2146321 ctgcttcata gaaaggatat tttcttttta atttttgttc agcgattgct tctccaatat 2146381 aaatggaatc gtaaattttc ataatagaag atccgtcgct aagacttttt gccgtccccc 2146441 atgcggttaa aggatgtccc atctgcccct tccagtcact aagcttcatg tcatatagta 2146501 gctcatcctc gacgacaaaa ccgcttttta caagtgactg cttcaaaccg agcggaaaaa 2146561 catgctgcgg cgacgctttt aaatggagat aattcgcatc aagcagcttt ggtacggagg 2146621 gtaaaaagtt aagtaaccgc tccaatggaa acgtatcatg gagctgaaca aagttatgag 2146681 aaaaaatttg cggaagctgc ggatctctgt atacgctgta atgatcaaac gatgccgatt 2146741 cagacgttaa caatatatat tgatgttccg tttttgaata atgtcctgtc atgaacgtct 2146801 cctttttatg acctatacct ttactctgtt gcaatattca atttctttat aatctcatcg 2146861 tacaccggat aaaacggctt tccaattgga aattgctgaa tatttcggaa agaagcggag 2146921 attggcttct gatgtaaaaa aaacttcctt gttacttgtt cactaatcgg gtgaaagacg 2146981 ccgtttagaa acaaaaacgg ctcgcgttcg atgaaaaaca gacgtcggcc aggcggattt 2147041 ttgatcaatt cagatcgttt ccacgtaatc ggcggccctt ccggaagcgt ctccatctct 2147101 tcttttccaa ttgtcactat gtcttttctt tgaaattgat aaaattgaaa cgcatactgg 2147161 tccacaattc gccttttttt tccggcttcg atataaaata ttgcaggatg gtcagcttcc 2147221 tttactaaaa tataattcgg aatgtttaaa attttgccaa tcctatattg gaataaatat 2147281 gggtctggaa cagcgacagt ccgatttaga tacaaaaaac cccacttttc tccaacagga 2147341 tgccttacac cctgatcaaa aaaatacaca ttttgatctg aaccttttac aaaagagccg 2147401 tcaatcaaat cggcgggcag aaaccgatat gcattttgaa atgaatctgg ggttttatag 2147461 gttgtgtcta atacttcatt tatcggcaga aatggggtaa agttgttgag tctcgcccaa 2147521 aaaattgcgt cgccatgatt ccaatgcttc atatcatcat cccagtagcc tccaaattta 2147581 tggtgaatga gattaagtaa cgaacggcga tgcataactg agcaatgatc aacttgaaaa 2147641 gcggcctgat caagcactgc attggcattt ctgtagaaat gtgagatttc ctctcccctt 2147701 tcgtttacat gtacaacttt ttgttttgaa tagaccgcct gcgcttcagg cttatgtgaa 2147761 aactcttgca ccatacggct cagccgctca ggatgataaa cagtgtcgtc agtaagatag 2147821 gaaatgtaat cgccgtctgc aaatgggagc gcactgttaa ttaatgtggc ataacgggct 2147881 gtttttaatc gatctgcagg atgcacgaaa ctgttatgat attgaatgcg ccggtcatgg 2147941 agatacttgt gaatcaccgc agttgtttct gcattcgaat gatcatccat gataaaaagc 2148001 tcccaaagat catgcgtttg ctgtatcacg ctttcgatcg ctttttgcaa ataatcgggt 2148061 ttgttgtaac ttgttaaaat aatagacact ttctctccca tctataccgc ctcccgccgt 2148121 caaacataaa aacggctccg cagcaagcag agcctctgtc atcatttaaa aagcacccca 2148181 gcttacaaca cttgagagtg aaacatgaga tctcgtgtta tttaacgggt tttggaaaat 2148241 aaccaaatca gtcagaactt cttttacgat gacattttga agtgtatctc cgttgatcaa 2148301 attgactttt gaaaccggta cgcccagctc ttttgcaaaa acaagctggc gtctgaggtc 2148361 agatggattt ccttcagaag acgattgacg tatcagcaga atcagcaaaa gcaaaataaa 2148421 atgcagatca tcttggtttt cttctcgatc cacttgtttc tctaaatcca aatcatccct 2148481 ctcccttatc cttatctctg tttcacaata tgtgcgactt cgatttatgg tataggctat 2148541 gtccactcca ttaaaaaatc agcattttcc ttaaatagat gaaaaataga tcaggtacgg 2148601 cgttcgactc ataccaaata acagccggaa gaatatgaat aacgtgagtt cactatcgaa 2148661 taggaggtgt gtgtaatgag ctctgaaaat gcacagttaa aaaaggattt aattaaagcc 2148721 gttttaagcc ctttatttcc aactgcaaca gaaggaggag aaaatatgga tagtaatctt 2148781 aaagccttgc ttgatgctgc catcgatcaa aaagtagatg aaagtgaaac ggttacggca 2148841 gaatctattt tagacccttc tcttccggca agatggattt ttgccagaat tacgccaggc 2148901 actacaatca gcattgtgac tgattcaggt gacatgatcg gaccggttgt tttcgttgct 2148961 ttcgatcagg ttcacgggat cgtatttgta acacaggaaa gctccgtcac tccggcaggc 2149021 caagctacaa cattaattga tgtagacaaa gtagaaagcg ttacgttctt ttcataacat 2149081 ccgatgaaag tcttgtatat ccagtcggga tacggaggaa tatacagtta ttttgatcgc 2149141 tgggctgaag aatgttttca gaacactcat acagagtata tgattgcaga taaacctgaa 2149201 gcagaatctt tgatgaagat cgaagcgttt cagccggatt tcacacttat gatggttgga 2149261 gaccgcgttc ctcacgactg gctgacctgg ttaaagggta aggatatccc cgtgtatgtt 2149321 tggctgaccg aagacccatt ttatatggat atcagccttc aggtaattaa gcttgctgac 2149381 gccatattaa cgatagaaca aaatgcagct ctctactatc aagagctcgg ctaccagaac 2149441 gtctattatg ttccgatacc agttaaccat cggctgttta aaaaaatggg caccgaacat 2149501 tcctatcatt caaatctgtt aatcatcggc tatccttacc ctaatcgggt tcagcttatg 2149561 aaagaagcgg tccatctgcc attcacggtt cgggtaatcg gcaaggaatg gggaaaatat 2149621 ctgcctaaaa aagtgctcaa acagccgcat attgatgtcg tcagcacatg ggttccaccc 2149681 gaacaggccg ttcattatta taatggggca gacatcgtaa ttaatgcgca tcgtccctat 2149741 cattttgctt tcaaccaaaa tactatgcgc atcaaaaatg ccagttttaa taaccgaacg 2149801 tttgatatcg ctgcatgcga agcatttcaa ttaacagatt tacccgcggc gcatcctttt 2149861 tcatccatta tttcttatca cggcatgaac gactttaagg aaaaagccgc tttctatatc 2149921 aaccaccctg aagaacggca aaaagctgca gcagccaatt ataaagagac cgtacccgca 2149981 tttacgtttg atgagcttcc tgcaaaacta aaagcgattc atctggcgct ttcttgaaaa 2150041 atcgttcatt gctatgaacg atttttttat tcatagaaaa aagcagctgc acaagctgct 2150101 ttctattcta gccgtcagaa cggtctttca gcttcctcgg atttacctgt ttatgaagat 2150161 caggcatttc gccgagatgc tgtgcaattt gttcccacga tacaattttg aaattttgat 2150221 tgacggcttg tccgttatca atattttcgc cgtcctgcgc cacaaaaatc ccgtacggat 2150281 attttgggcc aagtccgaaa ccgagaacat caataccatc cgtgtcacta gtaccgtcta 2150341 tcttctcgcc atctgtaatc tcaaagttgg ctacatagcg atttttcccc tgccgttcat 2150401 acattgcata gctgttattt ccttgacttg aagccatgag atatcctttg ccatttggtg 2150461 cataatagat tgtcagtcct tcaatatcag ctgtcaaatg atctcctgtc gcacggtcaa 2150521 caacctgccc ctttgaccct ccgccgggct cagcgttaaa tttccagatg gcctcatctt 2150581 cctctgctat gtataggttt ccgtactcat catccgcaac aaggccttcg gtctgagaat 2150641 tcaacttaaa ttcacgcacc tttttccctg ttacataacc ctttccacca tcaacaattt 2150701 catactgctc aaattcccct tgtttgcctg tcactaatgc gtaaaatgct cctgttttct 2150761 ggctgtgata caagctgaat ccataaacct cagaaatatt ggtggaaata ggatggttcg 2150821 gatctgtaat gcttttcaat tttcctttat ccccgtctat tgcatatact tcaattgtat 2150881 tttttccttc ggaccggttg gatgcggcag caatatcaat tttttcgccg ttcaatggaa 2150941 aatcatagcg cagatcgaca ttattgagct tgccaaactc ataagaatga agctgttttc 2151001 cgtctaaatc atacacaacg agccctgact tcttatttgt tgtaatcaac ttgctttttt 2151061 ccgggtgttt ttcatgaacc caaatggccg ggtcatctgc tgcatcatcg ccagatgcga 2151121 ccggatctgt ctccgtgtgt gcagtcactt tgaaatgatg ttcctcattc acataatgag 2151181 ccgacaccga ggttgctgtc aggctaagca ataaacccgc ggcagtgctt agcagcattg 2151241 tttttggaac cttcatttgg taccctcctc ttttatcact aacactacta ttgtaaaata 2151301 tatacaggtg attaccgtga ggaaaatgaa ccttttttta tagggtttct gactcataaa 2151361 caacttattc cccaaagagg tggtgagatg actttgccag atttactttt gcggagcgaa 2151421 ataaaaatat gttgaatatt tagtacatta tttatttagt tttgtttttc cctagttacg 2151481 tccgtttttc cattttctat taaaaaagaa cactttgtga catgatcatt cccctaaatt 2151541 ttgttttatt ggttgctttc attaattcga ttacaaagtt gaacatatga tgcatggtag 2151601 agaaacgaga gttggaggat aagccatgcc taaacagcaa acagcagaac taaaaccatt 2151661 tttccataac aaaacagttt tagtcactgg cggaacgggt tcaatcggga gtcaaattgt 2151721 caaacgcctt ttgatgctta cacctaaaca ggtgattgta ttcagcaaag acgacagtaa 2151781 acagtatgtc atgagccaaa agtatgcgga ggataagcgg ctattatttg tacttggaga 2151841 tgtacgcgat cacagaaggg tgaatcaggt gatgaaaggc gtcgatatcg tctttcacgc 2151901 ggctgcgctg aaacaggttc cgacatgtga ggaccatcca tttgaagcga tccagaccaa 2151961 tctcatcggc ggacaaaatg tggtggaagc tgccctttca caccgagtgc agcatgtcat 2152021 taatatcagt acagataaag ctgtatctcc tgtgaacaca atgggtgcca ccaagctgtt 2152081 atctgaaaag ctgtttcatc aagcaaaccg ccacgtccaa aacaaaggaa ccttgttttg 2152141 ttcggtccgc tttggaaatg ttctcggttc cagaggttcg gtcatcccca tattatttga 2152201 acagatgatg gagggtgaac ctctgaccat cacagacaaa aacatgacca gatttttcat 2152261 gtcaatagac gatgcagcta cattgacatt acaatcggct gctattacaa aaggcggaga 2152321 aacctttatt ttcaaaatgg aatcactgaa acttgaagaa ctgattcatg ggtttgaaga 2152381 atatgcatcg cagcacgggc tcccgcggcc ggctgcagta gaagtgggca agcgtccagg 2152441 tgaaaagctt cacgaagaat taacatctcc acatgaaatt gaatcactgt atgaatgggg 2152501 caacctttat gcgatccttc cagagccgga aaaacatcct gactttcgca aagtcaatct 2152561 gcctgggtat caatcagatc aagccccgct cattacgaaa gaaagaattg ctcagattat 2152621 tgaagaattg catcaagaga aaaaggcata aaaacaagcc tgtctatcca ttaggcaggc 2152681 ctgtttttaa cagtttattt attaaagaga tgcagatagc tttcgtatcc ttcttctttt 2152741 agcttatgct tcggaacaaa ccgcagcgct gctgaattta tgcagtaacg aagtccgttt 2152801 ggccccggtc cgtcattaaa tacgtggcca agatgagaat cagcagttcg gcttcttact 2152861 tctgtgcgaa tcatgccgtg gctcgtgtcc agtttttctt ccacttcttc ttcaatcggc 2152921 tttgtaaagc ttggccagcc gcattgggaa tcaaatttat ctttggatgt aaacaatggc 2152981 ttgcctgaca caatgtctac atacaaccct tcttccttat gatcccaata ttcattttga 2153041 aatggcggct ccgtgccgtt attttgcgtt acttcatatt gcatgcgatt taatgacttt 2153101 attttttctt ctttattgta cgccatttat ttagcccccc aatgctcgct gataaatccc 2153161 gctcgtccgg aacctgtccg gtagcgctga taatgtgctg gattcttttt ataaaaatgc 2153221 tgatggtagc cttccgcttc atagaaaggt tcagctttta aaatgtccgt tacaatcgga 2153281 tctttaaaga tgccgctttc cgccagacgt tgcttggaag cttccgcaag ctccttttgt 2153341 ttatcattat gataaaaaat ggctgcgcga taggaactgc cgcgatcagc aaattgccct 2153401 ccggcatctg tcggatcgat ttgctgccaa aataattcaa gcagtttttc ataagggaat 2153461 acatcaggat gaaacgtgat ttgaacggct tcacgatgtc ccgtcgtttc actgcacacc 2153521 tcttcgtacg tagggttttc agtatggccg cctgtatacc cggacaccac tttttcaatt 2153581 cccggctgtt cgtcaaaagg tttaaccata caccaaaaac agcctcctgc aaatgtggcg 2153641 atttcttttt tttcagacat actggtgcct cctttgttaa tacgtggtat tattatatta 2153701 tagcatgtaa aaatagaatg aaaatgattc tgcttttcaa taaaatctat aggttttaag 2153761 caatatgctt atgtaatgga ggttcacaaa tttgaaagta agaacacaga tgatgtacga 2153821 tatggaaact ttactccgta aagtctttaa acaaatacgc aatgaaatca atgaaatttt 2153881 agataaagag ctgtcgcgga atgaattcac cattcttcga atccttagtg aacaagggcc 2153941 taaaaaagtc actgaatttg cgcctatttt agaggtatcg gcaagccaca ttacggctgt 2154001 gaccgatgcg ctggtagaaa aggaatggat tacgagaatc agatcgaagg aagacagacg 2154061 catcatccgc attcatatca ctgaagcggg cgaaaaagtc cttcagcact ttaacgagaa 2154121 aaaaacggaa tatttcttta aacgctttga ctgctacact gatgctgaac ttgccacgtt 2154181 aatcgagctc ttcagcaaac ttgataaaaa acggtgaaaa aaagcacata ccgatatata 2154241 ggtatgtgct tttcgcagtg cttcacttat ttttcagtaa acagcttcat tgctttccag 2154301 cggccatatc tataatacaa aaatgccgcg cagctgctaa ataaaaaact cattccgatt 2154361 ccaagcccga ttcctttttg tccaagccaa gctgaaaata gagctgtgaa aggatacctc 2154421 aacacccaaa acgagatcaa atttaatacc agaacctgca gcatcgctcc cgcggccctg 2154481 acgattccgt tcagcacaaa attaacccca ataaaagggt agaaaaacgc gatccacttc 2154541 aaatattgtt caccaaatgc gaccgcatca ggctcactga taaataacct tatgaggtat 2154601 ttaccaaata cccaaatcat aaccgcaatc accagcatgc aggaaataac agctatcaca 2154661 cctagccttg caattgttcc cactcttttt tcgtttccga ttccaatatt ttgccctgcc 2154721 atactattga cggccgtacc ggcagccatt gctggaagcg tgatgatgct atcaagccgc 2154781 tgcaccgcgc caaagcctga taccacgtga tccccgtatg agttaacaac actcataatc 2154841 gccatcatac cgcctgtaat caccatcatc tgcagacctg ccggaatccc gagtttcaaa 2154901 atcagcgcgg actcttccca cttgggcatt ctcggaatcg agaatggcac aagcttgtgt 2154961 ttgatgacat aaaacaaccc atacaaaaac gcaatgccct gtgacaaaat cgttgaataa 2155021 gccgctcccg ctattcccat gcggaacaca gaaataaaga gcggcgcaag cactgtattc 2155081 agtacaacag caaacgcaat aaaccggaga ggtgtcttgc tgtcgcccag cgcacgaagc 2155141 acagtactga taaagttata accaaacaaa aataaaatgc cgataaattg aatctgtaaa 2155201 tacgtctcag caagcggtat cattgactcc ggcgttttta gaagacgcag caaaagctct 2155261 gagagaaaaa aaccggccgc gccgaatccg atgcttaggc ctgttaataa aacaacaaaa 2155321 gcgttaatat acgacgccat tccttttata tcatcttttc ctttttgctg agataaaatg 2155381 gttaacgtcg cattgttaag gcccaaaata aaagacagca cggtcaaaac aatcgtgctt 2155441 gataccgcgg ctgccccaag ggcctttgcc cccagtaaat tgccgatcca caagctgtct 2155501 ataaattgaa aggaaacctg caatgcgttt ccgagcataa taggcattga aaacagtaca 2155561 agctgtttca gcacgttccc ctgtgtaaaa tcgtatgctt tcatcttttc tccttgtgtt 2155621 ctcaaatttt cttcggacca cacgaaaaaa gagacgttgt ttcatgtctc ttttttcatg 2155681 acttatcggt tttttttcgg tctcgcatac cgaatgtaaa caccatcaca cttaggaaca 2155741 aggcacaata ggaaacattc aaatacattt gatccatatc ttcagcagcc agatgatgat 2155801 aagcaagcca gccgaagtac agggaaaatg taaaggataa taaactgaaa tactggtaaa 2155861 tccgtttcat tttcagtcac ctctattgtt taggatggta ataggaaaac tcaatttcat 2155921 ctttttctaa atttatctta tccgctttga catacattcc attcgttaaa ggcatttctg 2155981 acaaacgcac ttcaatgctt ttatctccgg ggtgaacatg gacaaatgac ggcaattcat 2156041 aaaagctgtc catataattt aacacaaagc taattggtat actcaatttc cctaacgaaa 2156101 atttcgtgac attcagctct acatcaccgt tttttttcac ggtcggctca aaagcgataa 2156161 acgcatcaat agacgtggaa aatgccttga ttttccctgc gacatgaaca tcatcatcaa 2156221 tctctacttt ataatcaagc ttgtttgatg ctttgtcgtt taaatatgag ttaacaaacg 2156281 cagctaatga ttcttttgtg cttgtcactt gaaatccata ctcgctctca gatgcatctt 2156341 tcacctgagc ctgttccccc ggaagcaaaa caagtgccac aaacccggcg gcgaggataa 2156401 aattgattgc aagcaatata aaaaacagtc gcttccactt attcatgctg tcaccctact 2156461 ctttcggtaa tccttctttt ttaatggctt gatagacgcg ctttgcgata agagaataac 2156521 ccgtaccatt aggatgaaaa tcatcttcct cagaaattcg gctgctgtca cttttttgat 2156581 taaacaaatc ttcgatatgg acgatttttg catgtttatc ttttttcagc tctttttcag 2156641 caatatggtt ccaatccgtg acgacaccat ttatttcatt tagttctgat aatgtaaacg 2156701 taaacggatt gtacatgctg acataaatca gctcagcgtg atcattcagc tcgcgaattt 2156761 cagaaatgat tttttcaaag cgcttttcgt acggtttttc cgcttcctga aacggttcaa 2156821 cggttaattg cagaaagttt tggcgaagga ttttcatcaa atcattaccg ccaattgtaa 2156881 aaaagacata atctgcgtcc tttatgcctt tttgaacctt tttatctttt agtttttcta 2156941 ataaatcatc cgaacggttc ccttttacag cataattttt cacgtcgacc gttttgactt 2157001 gtttatctga ccggatagaa tccgccacct tgccgacata tccctttccg tcgggatctc 2157061 cgactccttc tgtcagcgaa tctccgacag ccgctatgac aatgtgttct tttgttttcg 2157121 tttcatgggc tttttgtttt ccctcagatg atgtacgtat gctcgtacac gcagtaagaa 2157181 gcaaaatcaa actggccatg attgaaaaaa tgcgcagctt caatcttgtt gctccttccc 2157241 attctactag tggaaagtgt atcatgtttt agaagatttg caaatgccta gtctcttagc 2157301 ttacttgagt gtactggctg acttcacatc ggaaatgata tcatcgtacg gtgtattctc 2157361 cactccattg taatctttca gcaccttacc gtccggacct accaaataaa aagaagattg 2157421 atgaatcact tggtcctctc cctccggctt ctttacgatc gctttaaagc tcttaagtgc 2157481 gaactcctca atctcactct ggctgtatcc cgtgagaaaa tcccagttat caaaagataa 2157541 tggataattt gcggcaaatt tcttcagctg tttcggctta tcgttttctg gatcaacact 2157601 aaatgatatg atgcggacat ctatattttc ggctttcagt tttttttgca gatcggtcat 2157661 atgagcggtc attggcggac atatagtttc acaattggta aaaataaaat ccgccagcca 2157721 tacttctcct tttaaactct ctaaagaaac gttcttgccg tcttggtttt gaaatgtaaa 2157781 aggctccacc tcgtaattga gcggatcttt aatctgctgt cctccgcatg cacacaaaaa 2157841 cagaaaaatc agcccagccg ttaacccctt gataaccttc atgacatcca tcctttccag 2157901 ccagcataaa aacgctttct aaaaccgtcc ttactgtccc atgtttgtat tcgatactga 2157961 gcaaaaaaaa tcctgcatgc ctccccatta acgattacaa aggagggcat gcaggtaaaa 2158021 aacggcatgt tacgcgttgt gctttaacac ctcttgatga aatacagcct gataatctgc 2158081 ccacttcatc cgccgcttca tataatgtcg gaaagaatac acttttgccc tgctgtttga 2158141 tgaaaacact tcttttaagt agaattgcaa atggtgatgt aacataaaga aatagtgctc 2158201 atcttccttt aatacaggta tttctgtcac tttcacctga atcccgtcac cgcgtttgaa 2158261 ctctaggctt ttgagtaaca agctatcaat cctctttttt gtttttcttc tattatatat 2158321 gatgccagcc gggctgtctg tcattttgcg cggttgtgta aaaaaattag attagcaaat 2158381 ggaacaagtc ctcatccttg ttcacctcta cataatgaaa cggttttttg ttcatccgtt 2158441 caatcagcgg cccataatcg gctttgttct gcagctcgat gccgacaaga gcaggtccat 2158501 tgcttttatt atttttcttc gtatattcaa accttgtaat gtcatcattc ggcccgagga 2158561 cttcgtcaag aaattcgcgg agcgcccccg ctctttgtgg aaaattgacg ataaaataat 2158621 gctgaaggcc ttcaaaaatc aaggaacgct ccttcatttc ctgcattctt ccgatatcgt 2158681 tattgccccc gcttaccaca cacaccacgt ttttcccttt aatttgatcc ttgtacaaat 2158741 caagcgctgc gacagaaaga gctccagccg gttcagcaac aaccgcacat tcgttatata 2158801 attcaagaat ggatgtacat acttttcctt caggcacaag gagaatgtca tcaacgacag 2158861 tttccagcgt ccggaaggtt tcctcgccaa tttttttaac agccgcccca tctacaaact 2158921 tatcaatttt atcaagtgtg acgacatgcc cagctttgtt tgattcaaag taggatgccg 2158981 ctcccgccgg ctcaacagca attacctttg tatcaggaga cacgtttttc aaatatgtac 2159041 ctaccccaga gagaaggccg ccgcctccga cacttgcaaa aagaaaatgc ggttctgtat 2159101 caatgtcgtt taaaatctcg actgcgagcg ttccctgtcc ggccatcaca tccggatcat 2159161 cgaacggatg gataaacgtc cgagattccg cctcacagca ttcagcagcg cttttatacg 2159221 cgtcgtcaaa cgtatcgcct gtcaaaataa tatcgataaa tccttttccg aatagttcaa 2159281 cttgagatac tttttgtctc ggtgtagtag acggcataaa aattttcccg tgaatgccaa 2159341 gatgtttaca cgaaaatgcc acaccttgag cgtggtttcc ggcacttgca cacacaactc 2159401 cgttctctgt ctgctcgctg gaaagctgtt tcattttatg ataagcccct ctgagcttaa 2159461 aagatctgac aacttgcaag tcttcgcgtt ttaaatagat attgcattca tatctctcag 2159521 aaagtctgtc attcctctgc aaaggtgtgt gaatgacaac gtcctttacg ttttggtgag 2159581 ccttcaaaat gtctttcact tggatgagag agttttcttt aagcaacggt ttcatgtaca 2159641 gattcctttc ttgttttaaa tccctattta atatgccatt ataacatgaa tattcaaaaa 2159701 ataagacaat tatttttatt taataattaa aaaaatacag actatgtcca ccacatcttg 2159761 tggtaacttc tgttcaacca ttatcctgca gagccaagaa aaaagatgat cgtaaaataa 2159821 agggtgtttt caaccaaaag gcatgatata atgaaaccaa ttagaaccaa aaggagccaa 2159881 ttgatgaata gtgcaccaaa actcaataca tttcaacatc taatcggaga acatcaaact 2159941 tttctggaag cgaagcgaat cgccaagcag ttctcgttat cggagcttcc tgtcttaata 2160001 acaggaaaaa tcggaacagg caaaaatcac ttcgcacatg ccatacactt ggaatcttcg 2160061 agaagcaatg aaccgtttat aagcgtcaat tgcagcaccc attcggaaga aacccttatt 2160121 catgagcttt ttggccctaa cggaaacaca ggtgtttttc aaaaagcggt acgaggaacc 2160181 ctttttcttg atgatgtatg gcgcatgcct gcttctgtac aagctcagct gttaaaagcg 2160241 cttgattcag acacggagaa accgcgaatg atctgtgctt ctgcagaccg atccgtggaa 2160301 catacattca ggcaagactt attctacaga ctgaacattt taacgctcac actgcccgaa 2160361 ttatcggaac gaaaaagcga tattccgctt ttgacacagc attttctctc aaattctggt 2160421 cagcaattgt taatcgatcc ctccgttttt cccgtgcttg agaagcatgc atttgaaggc 2160481 aatgtcaggg aattaaaaaa cgctgcagat tatatggcgg cagtatcaag cgggggaacg 2160541 attcagccat atgacctgcc gccgtatatt agaggcacga tagacggaaa aacgtcgaag 2160601 aaaaaagcga aactgcttac tttaatggaa aaagctgagt ttttgtttat tttggaaaca 2160661 ataaaagtat tgaacgaaaa aggagaacct gccagcagac ggatcatttc tgaacacagc 2160721 aaaaataccc aaacctcgtt aactcctcag caggtcagaa gccgtctcga ctatttggag 2160781 aaaaaagatt atgtcaccaa aagccgcgga cgcgcaggca caaaaattac ctttgagggc 2160841 ttgagcttta tagagacgtt aaaaaatcaa atgatctagc gatcgaaagg agaatgtact 2160901 tgtttacaat caaagaagag atcgccaatg cgattacaca cggcatcggt gtcctcttat 2160961 ccatcccagc attagtgttt ctaatcatat ttgcggctaa ttacgggtct gcatgggaca 2161021 ttgtcagctt tacaatattc ggtgtctcta tgctgctgtt atatttgagc tccaccctgc 2161081 ttcacagcat cacacataaa aaaacgaagg acattttgga gattattgat catagcgcaa 2161141 tttacgtact catcgccgga acctacacgc cttttttgct tgggccgctg aaaggcacac 2161201 tcggctttac cctgttggtt atcgtatggt cacttgccct aggcggaatc gtttttaaaa 2161261 ttttctttgt gaaacggttt atcctattgt caaccttcgt gtatttagtc atggggtggc 2161321 tgatgattat tgcagttaaa cctttatatg cttcactgag cggagcggga ttcagcctcc 2161381 tttttctcgg cggcatttta tactctgtcg gaaccatctt ttacatttgg aaaaagatcc 2161441 ccttccatca cgccatttgg cacagctttg tattgggcgg gagcgctgcc atgtttttct 2161501 gcgtgctctt ctattgtgta aaggtgcctt tcctttcgta acagtaacag aaaagcgcag 2161561 tcttcacgac tgcgcttttt tatgcacgta attgtttttc attggcaggt atataagctt 2161621 ttgaaaagga caattcaatg tctgccggtt ttaagcgttt aaaaaacgag ccattttgca 2161681 tgttatctgt tcctttcgtt tccaccatca ccaacggaag atgatagcgg gccgcaagtt 2161741 ctacaggatc aatagaacca tctagtgaaa gaatcaggct ttgtcccttt tccagctgtt 2161801 ttgtcacatc ttcatatacc ttttctgaat ccccgtctga aatcacatcc atccgatcca 2161861 gccattgccc gataaaaggc aagcggaaca cttttgggtt agcgataaag ccggccggtt 2161921 cctcaatata tccagcaatt aaggccagtt cagccaaacg caaacgggga tgcacataca 2161981 aaacaggacc gtgtggtatt ggctctggct gatggatcgt cacaactgaa ccggagatgc 2162041 cgatacagcc ttctaaaaac gcctttggct gttcgtacac aagagccatc tgttttttgt 2162101 atgacagacg gggatcgagc attgtttgat taaataattg tttcatattt tttaacagca 2162161 tatacacaat ataaaccact agaaggctgt agcgaaccaa ttaaaatcct cccgctttag 2162221 aagaattctt tttttcatac attagaaatt cgtaatcata cgggtttttt tcgtctttgg 2162281 tcccctgctc agaagaaacc agcttccaat tggattcatc aaattcagga aagtgacggt 2162341 caccctcaaa ctcgtgatga attttcgtca tatacagtct gtccgcataa gggaacaggt 2162401 ccgtatagag ctgagcccct ccgatcacaa agcattcttc agggcctgaa caaatgtcca 2162461 gtacatcctt taatgaactg acaaccgtgc atccctgaaa ttctgaatcc ggcgctgagg 2162521 taacgacaat atttttccga tttggaagcg gacgtccgat cgattcaaat gttttccggc 2162581 ccataatgat tgaatggccc gatgttattt tcttaaagta tgcaagatca ttgggcaaat 2162641 gccacggcaa atcattgtct ttgccgataa gcctgttggc atccatcgca aaaatgaatg 2162701 aaatcatacg ctgaccgccc cttttatatg aggatgcgga tcataatcct cgatgataaa 2162761 gtcctcaaat gcaaagttaa aaatagaatc aacctttctg gcgaaacgaa gctgcggaag 2162821 cggtctaaca tctctttcca gctgcaaatt gacttgttca atatgatttt ggtaaatatg 2162881 aacatcacca aacgtatgga tgaactcgcc cggttcaagc ccagtcacat gagcaatgat 2162941 catggttagg agggcataag atgcaatatt aaacggcaca cctaagaaaa catcggcaga 2163001 gcgctgatac agctgacagg acagcttgcc gtcagacaca tagaattgga acaggcaatg 2163061 gcacggcggc aacgccattt tatcaatttc accaacattc caggcgctga cgattaagcg 2163121 tctggagttc ggatttgttt taatatcttc aataagacgg gaaatttgat caatggtttc 2163181 tccatcagct ccccgccaag aacgccattg ggagccatat acaggtccaa gttcaccgtt 2163241 ttcatcagcc cactcattcc agattcgcac tccgttttcc tgcagatagc gtacattcgt 2163301 atctcctttt aagaaccaca gcagttcatg cgcaattgat ttaaagtgga gttttttagt 2163361 ggtgagcatc ggaaagcctt cccgtaaatt aaatctcatt tgatatccga aagtgctgat 2163421 tgttccggtc ccagtccggt ctcccttttt ctcaccatgc tctaaaacat gtctgcagaa 2163481 atccttatac tgtttcattt ttttcatcct ttaaaagtag tcttctagta gtgtaacaca 2163541 ataaaaaatc atttctgaac ccagaaatga tttttttata gtcagctgac gacaggcttt 2163601 tcatcctgtt ctttttcttc atcttgcaga tcctgatgcg tatgtgcaat tctgctcgcc 2163661 gctgctgcag caagagctgc cacaatatca tccaaaaagg tgtgaatacc gtctggactt 2163721 tcatcaagtt ccttaataat tccaatcttc tctttatcca aataaccgaa attggtcaaa 2163781 ccgatcgacc cgtacacatt aacgattgaa agcgggataa tttcatctat gccgtaaagc 2163841 ggttcatccg tttcaacaag gtgctgcagc ggttcgggga gaagtttctg ttctgcaagc 2163901 tgatcgagtg caaggcctgt caaaacagca tgaataattt cacgtttgtt caggactttt 2163961 tctacattct ccatgcaaac actgagcggc agatttggat tgtatttttc ctgaagtttt 2164021 tgaacaatcc gtgcaatatc ttctatcata acgccccgtt tgttcagcat atcctttgtt 2164081 atatcgacca tttcattcat tgtgtacttt ttcatgtcta atggcatctc ctttaggcac 2164141 tcatccagtt gggaggcgtg ttgcggtccc agtaaatgct cccaagctca tgatgtgatt 2164201 gaaatccatc ttctgctgta tgataatgaa aattaaacca gtagccgtca tgaggcgggt 2164261 ggtctcttcg cacatggaat ctgagaagat cttctccagt tgtccgattg taaacgttga 2164321 aaattttttc cgttttgccc gctgaaggca tgcttgagat cacaacatct tggtacgcct 2164381 catcatcttg caatgtcgct aaataatcac taatcacatt ttcgattttt ggcaggatct 2164441 ctttccgata gtcatcctca atgacaggag cgattctgct gccgaatttt aaaaaggact 2164501 gatcctcagc gctgtcaagg agctgttcct tgtacgattg aaaaagcagt tcaggatctc 2164561 gcctgtcatc cgactcatca tcgtacaggt catgctcatc ataaaaagcg gtgtaatcat 2164621 tctgctcaag actgctcggc tgtccggaag gcttgtccgc cataagggca gccggaggag 2164681 atacgagccc gaacgttaca atggtaaata aaaccacaag ggtctttctc atccacaatt 2164741 tcatgactgc ttattcctct ctattttatt gtcatgtttc tcttatttta gcacatccaa 2164801 aacatgcaag tcatgtacta tatgaaactg atatgcaaat taggagattc gttgctatgc 2164861 actttgtgta aaaacgctta caatatttca tgaaaggagg ctttccgcat gattgacgct 2164921 ctgtttgcca cagtttcact cttaacatta ttatactttg tcgtcatgga ggtcaccgat 2164981 taacagaaag cccgtgatat gaatcacggg cttgtttgaa tgacgccata atggaacagt 2165041 gctgtttttc ttttcatgac gttaaaacca aactgttcaa accgcgggct tttccagtgg 2165101 tcttttagca caacgctttt tctggcgact cgtaccgctt cattgataca tccttcgtgc 2165161 aaaacggaat cctctgccaa atcacgtaaa ggcgcgatgc cgtcagaggt ttctacaggt 2165221 tcatgaaaca ttggatcgaa ataaaccaca tcaacagagt tgtcagggag ctgcttgatg 2165281 tgttcaaagc aatcaccatt cttcacctgg attcttctca tcgcagcttg aagctcttct 2165341 atacccgttt cccatgaatg cagccccgtc ctcactaaaa cagacacaag atggtttttt 2165401 tcaatcccaa caacagaacc cgtttcgcct actgccatac ttgcgataat ggcatctgac 2165461 cccaacccga gtgtgcaatc taaaaacgta tccccttcag ataagccggc agcccgaagc 2165521 ataggttctt tctccccctg taagaagcgt ttggctctga acatcgctgt attcggatga 2165581 aaaaagaatt tggcaccttg tttcgtatac agctcaaacc gctctttgcc gaccacaagc 2165641 aaatcacgtt cagctgattt cagcaggtgc tcaaccgttt gtttattccg gccgcagtat 2165701 ggcatattta gctctttaga aagctgcttt gcagttttta tggtgtgttc agacggtcta 2165761 tagcttgttg ttatcatctt ctgtactccc aaaaagaaaa tgcccggaga acgggcattt 2165821 agcagtgcgc atcgaaggca gcagtcagat ttttcatgat ttcttccata tcgtgtcctt 2165881 caatttcatg acgcggaata aaatgtacga cttctttgcc tttcaaaaga gccattgatg 2165941 gtgaagaagg ctcctggcca gtaaaatact cacgcatttt cgcagtagct tctttatctt 2166001 ggcccgcaaa tacagtcacc gtattgtcag gtgttttgtc attctggagg actgcctgtg 2166061 tagccgcagg acgcgcaagg cctgccgcgc agccgcatac agagttaacg actacaagag 2166121 ttgtgccctc tgccttttcc ataaagtttt ctacttcttc cgctgttgtt aactcttcaa 2166181 aacctgctcc agtcagctcg cggcgcatcg gtacgacaag ctggcgcatg tattcttcat 2166241 aagccattga cataaaaaaa gccccctcta gtatccttca tctgaagtaa aggatactat 2166301 agagagggcc ggatttcaaa tgttcacgcc ttaaaataaa agaaagtgtc cccagctatc 2166361 tagattttca taataccgcc ggtgttggca cttgtcacaa gtttagaata acgtgccagg 2166421 tagccggttt tcactttcgg ttcaaaacct ttccagttcg cttttcgttt ttcccactct 2166481 tcttctggca cttgtacatc caagatgcgt ttttcaatat caacgataat atggtctccg 2166541 ttttcaacaa aggcaagcgg cccgccctca gcggcctcag gtgatacgtg gccgattgag 2166601 aggccacggg aggctccgga aaaacgtccg tccgtaatca atgccacttt tggcccgagt 2166661 cccattccaa cgatttggga tgttggcgcc agcatttccg gcatgccagg tccgcctttt 2166721 ggcccttcgt atctgatgat gacaacgtcg ccttctttta cttttcggtt gataatgccg 2166781 tcaagcgcct cgtcctgaga atcgaatacg acagccggcc cttcgtgtct tgtaatccca 2166841 ttctgtacgc cgcctgtttt aatgatagcg ccgtccggag ctagattacc gaataaaaca 2166901 gcaaggcctc ccttttcagt gaatggttga tccagcgggt gaatgacgtc ataatccttt 2166961 acttcatgtc cggcaatggt ttctccaaga gtttttcctg taacagtcag cgcatctaaa 2167021 tgaagcgctc cttctttctt cgaaagctca ttcagagccg ctgaaacgcc gcccgcttcg 2167081 tgaagatctt caataaacac atccgatgca ggcgccagct tagccaagtg cggcacgcgc 2167141 tcagcgactt cgttaatgcg ttctaaagag tattcaacgc cggcttcgtt tgcaagggca 2167201 agggtatgaa gaacggtatt tgtagaacct ccgagcgcca tatcgagtgc aaacgcgtta 2167261 tcaatcgctt ttactgtaac aatatcacgc ggtttgatat ctttgcgaat cgtttccatt 2167321 aattgcgcag ccgattttct cacaaactct ttgcgttccg gagatgttgc cagaatggtt 2167381 ccattacccg gcaaagcaag accaagtgct tctgacagac agttcattga gttcgccgta 2167441 aacatgcctg agcaagaccc gcacgttggg catccgaact gctctagttc ttgaagctcg 2167501 ttttcgttga ttttccctgc ttggtaggcg cctacccctt cgaatactga ggaaagggag 2167561 atttttcgcc cgtcacttgt tcttcctgcc gccatcggtc cgccgctgac aaaaatcgtc 2167621 ggaatgttga tgcgcattgc cgccataagc attcccggtg tgattttgtc gcagttcgga 2167681 atacagacca ttccgtcaaa ccagtgtgcg gatacaaccg tttccacaga gtctgcgata 2167741 atttcacggc ttggcagcga atatctcata ccgatatgcc ccattgcgat gccatcatct 2167801 accccaatgg tattaaattc aaacggaacg ccccctgctt ctctgattgc ttcttttacg 2167861 attttcccaa actcctgcaa gtgaacatga ccgggaacga tatcaatgta tgaattacac 2167921 accgcaataa acggcttgcc gaaatcctct tcttttaccc ctgctgcacg aagcaaactg 2167981 cggtgcggag ctctatcgat tccttgtgtg atcatattac tgcgtaattc tgccatggtg 2168041 atcctcctaa attctttcaa ttgtttgatt ggattttatt ttgacaattt tcagtttatt 2168101 tatgggctgt ttttgcaaat aagataaata caggccgccc tcaccttgtt ttgttctttc 2168161 gtgtttttat atttatatag ctttctttcg atttgaaccc tccaactatt aatattgtta 2168221 cttactataa atagttttcg gatatttttc aacaatattc gaaataattt ttataaaaag 2168281 tgaattcaca taaaaaaggt gcatgatctg cacctttttt atctttattc gccttttttt 2168341 ctgctttccg tcatttgttt ccaaacagaa ccttttgctt cttctccatg ctcaatacgt 2168401 tcaagcgcca ttttgacttg aaggctgacc tcaaattcgg ggtcatcttc ggcagcgcgc 2168461 aaagcttcaa ttgcactttc atcgccgact tcgtacagga acatggcggc acgccagcga 2168521 acaagcttgc tggagtcgct taatgacttg atcatagcag gaatggcttg aggatcgccg 2168581 atatcagaca ggcagtctcc ggccgttctt ctgactgata cagctttgtc ctcaagtgct 2168641 ttatacaata gaggaagaac atcaggtgtt tcaatcattc ctaagtacac aacagcctgt 2168701 cttctgatgg acacctttgg atcatccaat gccttctgta aaaccgggat atcctcttct 2168761 ttcggatcca tctgttccaa gtgtgcataa cgctttttcc agtcctcatc atccagcata 2168821 tcaagcgtta ctttatacgc tttgcgctgt acagcttgtt ttgcttcgcc ctttccttga 2168881 gcggctgctt cagtcagtcg tttcagccgt tcatcactgt atgccgcttg aagctcttct 2168941 gtcacatcat ggccgatttc atcaaagtca ccgaatctga caccttgttc tttccaagcc 2169001 cgctcaaaca caacattgga agcttcagat ctaagtttta agatcgcctg ctgaaagcgt 2169061 tcaggtaagc cgaagcgttc ttcccgctct ccatcggtta atttaacttg cataggaatg 2169121 ccgctgaaca tctgcacaaa aacttttacc tctccaaaag attcttgatc agaacgattt 2169181 tcttctgcgc tttcagcact ttccatccca aatgcagtgc ggacttgcgg taaaatgtct 2169241 ttccagtcgt atcttgcatt ccgttcaaca gcaagaaaat ctgcgacgtg atatacccct 2169301 ttaactccat ctattttaag gatttccgct ataacaagcg gtgcgccttc tgcttgctca 2169361 ggtttatagt tattgctttt gcccgccgga agctcttccg ttaagatgac tttcattgta 2169421 ttcgggcttg gtgtaggttc aattgatttt atcttcatga tcgtcctcct atagcatatc 2169481 tgtgacttat tctatcatag tcgctccaag ccttctatta cgacgtttcg gcatcaatcc 2169541 cgggtatgtc tttttctaat tggcggacaa attgaagcat aaaattgtgt ctttcttctg 2169601 ccagttcccg tgcagtgtct gtattcatca tatctttcag ccgcagcagc ttatgaaaaa 2169661 aatgagcgta ggcgctttgc tcatctccat aaaggccatg cccttttgcg cccgcaaaca 2169721 tgaaagctct cgcaatgccg acagcaccaa tcgcatcaag tctgtcagca tcctgtacag 2169781 cttttccttc aattgagagc ggctccttcg ccaatttccc cctgtcccga aaggacatcc 2169841 ttgttataat atgaatcacc ctgtcagcat tctcttttcc tactccgaaa aaaacgagct 2169901 gatcatatac ttcgctcaca gaaagcctga ccgtgtcagg cagcttcaca tcaattaaat 2169961 catgaaccaa agccgccgtt tcaacaatga acaaatccgc tttttccttt tctccaatat 2170021 acgctgcaag atctgctact cttgatacat gatgccagtc atgtccagag ctttcgtcag 2170081 tcaggataga ttgaacccat gtcctgattt gctctgcctg cttcaattcc ttcacaaaaa 2170141 caccctcttt ttattgctct aatagcttca cgatatcgtc ttccaactct ttcggatttg 2170201 tatttggtga ataacggcca acgatttctc catttctatc cactataaat ttcgtgaaat 2170261 tccacttgat cgccttagtt cccagcatcc ctttcgcatg ttctgtcaaa tacacaaaca 2170321 gcgggtgggc gtttttcccg tttacatcca cttttgaaaa cataggaaat gtaacaccgt 2170381 aatttgtttc acaaaattcc tgtatgtcag cctcttcacc aggctcttgg ttcatgaatt 2170441 gattgcaggg gaaccctaag atctccagcc cctcctgctg atatgtatca tataattcct 2170501 gcagctgctt caattgggaa gtaaaaccgc acttacttgc tgtattcacg atcatcagta 2170561 cctttcccgc gaaaggctga agtgtcatgt ctttccctgt gattgtacgt accttcatat 2170621 gataaataga catgtaagtc cctcctatgt ccttggtgct gattatttta ccttttttaa 2170681 atcgcaattc aaaatgtaaa catcaattaa gaactcataa gaaacctaac gatatgagcg 2170741 tcagttcatt atcaattcat atggctcgtt ttttatctta tcattctata aaacattaca 2170801 attccctctt acatctttga aaatcatttt actgtgaaac caaaaggcgt gtcagtgcgt 2170861 tttatttaaa gagttttctg ttgtttcccc ctcaacacgt atagatagat tgaaaattgg 2170921 cgtgaaaatt cctataatga agaaaattaa acggggaaat aatggaggtg gcacgttgcc 2170981 tattaatata ccaacacacc tgccggcaaa acaggtgctt gaaagtgaac atatatttgt 2171041 aatggatgaa agcagagcat ttcatcagga tatccggccg caaaaaatta ttatattaaa 2171101 tttgatgccg aaaaaaatcc aaacagagac tcagcttctc agattgcttg gaaattcgcc 2171161 tttacaggtt catttcacat ttttaatccc aagcacacac acgccgaaaa atactgcgag 2171221 agaacacctt gacgaatttt acacgacttt ttccaatatc cgtcacaaga ggtttgacgg 2171281 catgattatc accggtgcgc cgatcgagca tttggcgttt gaagaggttt catattggga 2171341 agagctcaag gaaatcatgg agtggagcaa aacaaatgtc acttcaacct tgcatatttg 2171401 ctggggtgct caagcaggtt tgtattacca ttacggtgtg gaaaaaattc aaatgccgaa 2171461 aaaaatcttc ggtgtgttcg aacataccgt tctttcaaaa cacgaaagat tggtaagagg 2171521 ttttgacgag ctatactacg tgccgcattc ccggcataca gatataaata tggaacagct 2171581 tcaagcagtg cccgagttaa acattcttac cgcatcaaag gaagccgggg tttgcttaat 2171641 tgtgtctaaa gacgaaaaac aagtcttttt gacagggcac cctgaatatg atacaaatac 2171701 gcttcttcaa gagtatgaaa gagatttgga acgaaacctt tctactgtcg aggcccctaa 2171761 acattatttt gcaaaaggca gcaacgagcc agtgaatcgc tggaaagcgc atgccacatt 2171821 attgtttatg aattggctga attattacgt ttaccaagaa actccttatg aatgggacta 2171881 atttttcttt ttttagtgat acgctgagca aaaaatatga taaaatacat ctgattcagt 2171941 ctgcgtataa caaaaattta aaatactgga atccaaatca tttaaaatta gcttaacttt 2172001 ttcactgcat taataattcg attatgtatt tgtgttatgt ttatgtatag acaataactc 2172061 cttacgatgc atgaagcttg cttgttgttg attacattga ggtgaattta cttgaatacc 2172121 aataaaagag tattaatttt gactgcaaat tacggaaatg gacatgtgca ggtagccaaa 2172181 acactttatg aacaatgtgt acggctcggc tttcagcatg taacagtttc taatttgtac 2172241 caagagtcaa atccgattgt ttcagaggta actcaatacc tttatttaaa aagcttctca 2172301 atcgggaaac agttttatcg tttgttttat tacggagttg acaaaatcta taataaacgt 2172361 aaattcaata tttactttaa aatgggtaat aaaagattgg gcgaacttgt cgatgaacat 2172421 cagcccgata ttattattaa tacatttccg atgatcgtcg tgccggaata cagacgccga 2172481 actggaagag tcattcctac cttcaacgtt atgactgatt tttgtcttca taaaatttgg 2172541 gttcacgaaa acgtggataa atattatgtg gcgacagatt acgtgaagga aaaactgctg 2172601 gagatcggca ctcatccaag caatgtaaaa atcacaggaa ttccaatcag gccgcaattt 2172661 gaagaatcca tgcctgttgg cccgatatat aaaaagtaca atctttcacc aaacaaaaaa 2172721 gtgcttctga tcatggcagg tgctcacggt gtattaaaga acgtaaaaga gctgtgcgaa 2172781 aaccttgtca aggatgacca agtgcaagta gttgtcgtgt gcgggaaaaa tacggcttta 2172841 aaagaatctt tgagtgcgct tgaagcggaa aatggtgaca aattaaaagt tctgggctat 2172901 gtggagcgca ttgatgagct atttcggatc acagattgca tgattaccaa gcccggcggc 2172961 attactttga cagaagccac agccattgga gtgcctgtca ttctgtacaa acccgtgcct 2173021 ggccaggaaa aagaaaatgc aaacttcttt gaagaccgcg gagctgccat cgttgtgaac 2173081 cgtcatgaag agattctcga gtcagtcact tcccttcttg cagatgaaga taccttgcat 2173141 cgcatgaaga aaaacattaa ggaccttcat ttagcaaact cctctgaagt gattttagag 2173201 gatatcctga aggaatcaga aatgatgacc gccaaacaaa aagccaaagt gctatcgtaa 2173261 tggcgtactt gagagcatac gaaaatcgtg tgctcttttt atttatattc agccatcaat 2173321 aaaagcggtt acattttttt atggaacttg cccttctttt gaaaaataag ccgtttcgca 2173381 acttgacggg tgctcccaga tggtgtatag ttgaaccatc atttaacaat gaatcaaagt 2173441 tagatgatga caaaattttt tttagcacat gggtgctaca gtactaggag gaattaagca 2173501 atatgcaaaa cggtaaagta aaatggttca acaacgaaaa aggattcggc ttcattgaag 2173561 ttgaaggcgg agacgatgta tttgttcact tcacagctat cgaaggagat ggatacaaat 2173621 cattagaaga aggacaagaa gtttcttttg aaattgtcga aggtaatcgt ggacctcaag 2173681 cttctaatgt tgtaaaactc taaactcaat acatgatgat gagatgacaa atagaggaga 2173741 ggcattcgcc tctcctattt gattttcatc tggatttcaa tcgccaaaat gttttgttta 2173801 cacctctgtt caatctcttc aacatacttt tccattgatg gttttccttt tttcgcgata 2173861 tcggccagtt cttctaaatc actgtatatt tctataaatg ttttgtgaag gatcaacttc 2173921 aagtctttat catccatagc tgcgttcccc ttctctatca agatacctca aatagtaaaa 2173981 cggtcctatt tattctggtt caatagttat atcggcttat ttttattttc ttttctattt 2174041 tggtacataa atttcaaaaa aactctgcaa aataatggcg gaggtgtttt ttgtgacttc 2174101 agaatttcat aatgaggatc agaccggctt tacggataag cggcagctgg aactagcggt 2174161 ggaaacagcg cagaaaacaa caggagccgc gacgagaggc caaagcaaaa cattagtcga 2174221 ctctgcatac caagccattg aggatgctag agaactgtca caatctgaag agctggcagc 2174281 tctcgatgat cctgaatttg taaagcagca acagcagctg ctagatgaca gcgagcatca 2174341 gctggatgaa ttcaaagaat aaaaaccgca gcttctgcgg tttttatttt tagtgattgg 2174401 ttaagacatc tccgtattgt ttcaactttt caccaaccgt acatttattg atacaaaatg 2174461 aatgcgcata agttttgcca aattctttgc gaaactgctt cttaataaaa cagtccttgc 2174521 aatattcatc gtgcagttct gtcagttctt taaagatcat tttcttatcc aatatcgtca 2174581 tctccgttac ggtctaattt cgtgtggctt tctacgaatt gatgggatag aattttttta 2174641 gcgaggccgt cagcttcctg attgtctttt cgttgtattg tttcgtaggt tggagtaagc 2174701 ttcagcgatt caaggagtgc ttctattttg tccagccatt cattatgaga tggatcataa 2174761 caaggccagc tgccgtcaag ctgattcagc acaacaagcg agtccccttt gattgtaatt 2174821 gaatttctgc ttgccccaag ctctcttact tctcttattg cttcataaag cgctgcgtat 2174881 tcagcttcat tattggtttt cagccggaag cttttatttt ttctcaagcg atgccgggtt 2174941 cctcccaatg aataatagat gacgatcccg agaccggcca gttcgctctc tttatcgaaa 2175001 ctgccgtcaa aataaacagt aatgtcatca ggctcttgag caagctcctc tgtcagcttt 2175061 tccaattcct tcagcgtcca gctgccgcct ttctcgtctt cgaactctag ctccttcatg 2175121 tatggaaaac ggccaagttc tctggcgaac gtacgtgcct gctgtgctgt cagccagtct 2175181 tcgctaaaaa atgagacgga tcccgttcct tttgcttcta ttttcaaatg cggtctgagc 2175241 ttcattacaa tcaccttacc attcattagt tgccgggctt atgctataat caaaccaatc 2175301 ttaccccgga aaggaagctt tttcatcttg tttaataatt cgttttggat cttttttgcg 2175361 atcattcatt ttatcattgt tcttttattt tataaaggat ttggcaaaat gggactgttt 2175421 gtttggatcg gttttgcgac agtctgcgcc aacctccaag tcgtcaaaac agtcgaactg 2175481 tttggcttaa cagcgacact cgggaatgtg atgtatggca caatcttttt tgcgacagat 2175541 gtgctgaatg aaaaatacgg accagctgaa gccagaaaag cggtatggct cggattctca 2175601 acgctcctga cgctgacatt tgtcatgcag ggcgtgctgc ttttcgaacc ggcttccagc 2175661 gacatatcac aaacagcgct ggaaacgatc ttcggattcc ttccgcgagt tgcgttagga 2175721 agtctgcttg cctttatctt cagccaaacg ctggatgttt atgtatattc ggcaattaga 2175781 aggatatttc cttctgatcg gcttttatgg ctcagaaacg gcggcagtac agcagtcagc 2175841 cagttgtttg atacattcat attcactgca gtcgcctttc tcggcattta tccggcagac 2175901 gtgtggcttc atatttttat ttctacatat ttgattaagt ttgcggtatc tttaatttca 2175961 ttgccttatg cctatgcagc caaaaaaatg atacctaatg atgaaaggag ttcataatgc 2176021 ctacagaaat atatgtagac ggcgcaagcg ccggtaatcc agggccttcc ggtatcggca 2176081 tttttatcaa acatgaggga aaagcagaat ctttctctat tccaatcgga gtgcatacaa 2176141 accaggaagc ggaatttctt gcattaattg aagggatgaa gctatgtgca acgcgcgggt 2176201 atcaatcagt ttcctttcga accgattcag atattgtgga acgcgccact gagcttgaaa 2176261 tggttaaaaa tataacgttt caaccgtttg tagaagagat catccgatta aaagcggcat 2176321 tccctctttt tttcatcaaa tggataccgg gcaagcaaaa ccaaaaagcc gatcttctgg 2176381 caaaagaagc gattcggctg aatgaaaaga attaaatctt gatcattggt tcatcctaat 2176441 ggcgaggtga actaacatga aaaagaaaga taaaggccgg ctgaccggcg gtgttactcc 2176501 gcaaggcgac ctggaaggca atacacataa tgaccctaaa acagagcttg aggagagagc 2176561 aaaaaaaagc aatacaaaac gctagagagg atctaaacga tctctctagc gttcagcttt 2176621 tcaagcatac gctcaattcc tttaatttgg tggcggcgaa gcatgtcagc cgcctgctcc 2176681 atttgcaaag taaataaagc gtctttcagt gtgcaggcca gcggcactga gcaatggatt 2176741 tccgcaagct tcctcgacat ctccaaatcg cttaaacctt gctgaatttt tccctgctgt 2176801 ccttttggaa gaagagaaag attttccaat aaacggtcaa tcgtttcgta ttcacgaatc 2176861 agtttgtagg ctgttttttc tccaatgcct ttgactccgg gatagttatc actggaatca 2176921 cccataagcg ctttaatatc aatcaaagcc ttcggcatta cgcctgtttc ttcataaaaa 2176981 gtctcttttg tatagacttt ataatttccg attccttttt gaagcaaagc aacgcttact 2177041 ttatccgtta acagctgaag taaatctctg tcccctgtta ccaccgtaat gtccgcttca 2177101 ttcgcaaata aatcggcaag agtaccgata cagtcatccg cttcatagcc ggcaaagcca 2177161 atattcatga ttccaagctc tgcggctgct tcctttgcca aatcaaactg cggaatcagc 2177221 tccacaggcg gcgcgctgcg gttggcctta taatcttgga acaagtcatt tcggtacgtt 2177281 ttgctcccca tgtcccagca gcagacgacg tgtgtcggct ggaatgtttc cacagctgta 2177341 atcaaatgct ttaaaaagcc gttgacgccg ttcgtcggca ccccgctgtc atttatcata 2177401 aagttgcgat gtacggccgt ggcaaaaaag gcccggaata aaagagccat gccgtcaacc 2177461 agcaatagtt tattattatt catcaaataa ctcccttttc tttcattcct tctattttat 2177521 cataaagcag cccaaaaata aaaaacagta tctctttaat tagagatact gtttgaatat 2177581 ttatcaatcg ttgtgtcttt tgttgctggc gatcagcttt tcagcttcgc gtcctgcgta 2177641 agagtcaaaa tgggtttgaa atccgttttt ctttttggcg ttgttattcg cctgtgcatt 2177701 tctgtttccg agctttgttc tgcccaacat gaatcccccc ttacgtcgga tgcatatagt 2177761 atatgcttcc ggcaggaggt tcactcgcga caggatcatc cagcttacat gcggcttacg 2177821 tattctctga ccatttcttt tgatacaagc cgtcttgtcg ggacgatgcc ttttttagcg 2177881 agctgattca tttgctcggt aatttcatta attgcatctg tagtataagg ctcatcgttt 2177941 ctgcatttag caacagcttc ttcaatcgcc aattcacgca tattttcaag acgcataaat 2178001 gctttgatat gctcgtgctg ttttgatgaa tgtgctgaaa ttgctttatg tacctctgac 2178061 attaatcgtt catctcgctt ttttctattt agtctatcat gacttgaaat acaagccaac 2178121 tgaattttac atttttattg tattgtctga atttttccag gagatgcacg cctgatacgc 2178181 catttcaatc tctttcgcat gttccccttc cgcatatcct cttaaatatg tctctttttg 2178241 atccgttatt tgcgcgattg ctttttcacc catatcttcc tgtaagcgtc tgaggtgagc 2178301 agtgtaatga gatatcaggc tttcttcttc attttttatc catgcctctg tgattttcgt 2178361 aagtttcatc cgtacagctt cgataaaggt cgcttttcct ttctgctcaa aaaactgctt 2178421 cggtgatttg atctctttta gttcctgctc aaaagcacgt tcttctattt ccggttcaac 2178481 ttccttcaac tgtatgccgt tcgaatgctg atcacccgca taaacggaaa aataaccgtc 2178541 ctcgtttaat gttttttgaa aatgatccag ccattcttca ttgatatgcc gttcgatgaa 2178601 accgctcatg cgaacatcaa gcgttttgat ttcctgaata tattcaaata gatattcatg 2178661 taaggctgtt gtcatcgctt tactgacgtt ctttttccaa tccccgtttt gcagcccggg 2178721 atgaaatgcc gattttaata aatcatttgc aaaatatgat aatcgctgtg caatgtgata 2178781 tagctgctct cttgtatctt tttttacttt ttcaatgatg gtttttgagt tccgccgttt 2178841 ctcgatatcg gccgctgtcc gctcaaatga cagcataagg cactgtttct gcgcttcctt 2178901 ctcttctcgg gactgatgct gggattggtg aagctgaaaa acagtttcgc atagtttgtc 2178961 tgcctccgaa ctgagctgcg ctgctgacgc tttttttaca tccacttcga taaaccggtc 2179021 taagtgtttt cttactttcg agaactgatt ataaaatgac tccggttttc ccaccagttc 2179081 ctccttactt gatacggtaa agagctgcgg ctcataaacc ccttctttta caagctctgc 2179141 gctgacataa tcggtcactg tttcgagctc tgttttatct tttgcaaggt ctgcagcatt 2179201 aataataaaa aacattttat ccatgctgag cgattctttc acaagtccaa gctttcgcaa 2179261 aaatgaacgg tctccttttg aaaaagagtg ctgataataa gtcatataaa aaaatgcatc 2179321 agcatctttg atatattgga atgccagttc tgtatgccgt ttattcatgc tgctcgcgcc 2179381 gggtgtatca acgatcgtaa tccctttttc agtgagcggg catgtatagt agaccgttac 2179441 ctctttcaca gcacaggccg ttgtttcctc tgctacatac ggctttaatt cagagagcgg 2179501 aatcgttaat ttcttctgtt cctgtatata ctgctgatac ttctcgtatg caagcaggaa 2179561 attgctgatc aatttcacgt gttcttcctg cagcctgttt tttttgactg ccttttccca 2179621 cttctctgtg aaggaacggc ctgccggctc ctttggtatt ccggtgagct gcaaaatttc 2179681 agccgttaag tcatcctctg tcttaaacac tacattcgct gttttgttta agttgccatt 2179741 gattggcttt gtgatcttgt taattgtcgc tgtggttggc gttggtgagg atggcagcac 2179801 tctttcgccg acaagcgcat tggcaaatga tgatttcccc gagctaaagc ctccaaaaag 2179861 agcgagtgta aatttccgtt cctcaagcct tttcaccctt tcacgaaacg ctgaagtttg 2179921 ctttaacaac atgctgcatt cgcctaaaat gtcagacaaa gtgtaaaagc gtttgatttg 2179981 gtcttgaagc ggcatttctt gttccatttt gatttctgat ttcggcatcg gctgcgccgt 2180041 cagctggctt cggccttgtt tctgctctgg agccgccact cttgttttct tcgatttaaa 2180101 ccattctgtg tctatatgca ttgggcatgc ggactcttct tcccaaatgg cccacaggcg 2180161 atcggttttc tctcgggcat tattctctaa acgtgcctgt tcttgaagaa agacaagttt 2180221 ttctgattct tggacgagcc ggtcgttaat tgtttgcaca tctttggaaa cacgctcttt 2180281 caccatagcg gagagcacct ttatgatgtc tgcggcttct cttttcgcct ctttccggat 2180341 gagctctgcc aagtcttttg tatattgcaa tacatattca gaggaaaagg ctgcaccatg 2180401 cttgaccgcg tgttcaatga tgcttatatc aagcggtgtg cgataggcct gaatcagctt 2180461 ttcactttca gcggtataga catcaaatac cttggcgagt ttatgaagcg tgtctatcat 2180521 atgccaatcc gcttcggcct ctgttcgttt tgccacatca gagaaaaaag cattccgcct 2180581 tttatctctt tcctgtgcag ttttcgcttt agaaaagaaa aagccggttt taaaggaagg 2180641 ctcttgtgat tctaaaaatg cagccgccaa ttcacgcatt tcaaaaggcg tcaggttggc 2180701 gttttttaaa atacgattga tttcttcctg catcctcttc tctgcctcag tcatttgttt 2180761 ttcggcctca tccaattgat cacgcagcga ttggaccagt ccagtatgga tattaagctg 2180821 ttcagcgaaa ctcggagcgc ctgtttcgtc tttcttcagc atttccgtat gttcctttag 2180881 cagattacgg actttttgtt cggttaaagc ctgcatattg ctttttgatt gctgttctat 2180941 tctgcttaac tcttctctca gggcccccat ctgattgaac gggtgatccg gttctgttac 2181001 tgatgtaaaa tagagcgctt cccttgaaat cccttcattg caaagcatct cctctacctg 2181061 cgcttgatag tctccaaatt tcgtctccgt ctcatcatgg cggtcaattt gattgacgat 2181121 aaaatacaca ttcggaatgc tttcttttat tgatctgaga aactttacat tttcctcagc 2181181 gtgcacgtga ttatagtgaa cgacgtaaaa cagcgcatcc gcttggtgaa gaatagaagc 2181241 agccgataga aaatgcgcat catctgttga atctatccct ggagtatcaa tatacgcaac 2181301 cccggaatcg atctcagtat acctgtcaaa aatttcgacg ctttcaatct gttccccgtc 2181361 tttacaatat tgctgcacct tgtctttctg gtaagtccct tccagctcag cacacgctcc 2181421 gtctgttgta tgaagccgaa ctcgcttttc cccgtttctg atcacaacaa ggttagcgct 2181481 tgtcggaatc gggcttgtcg gcaaaatatt ctccattaac aggcagttca gcagtgacga 2181541 tttccccgct gaataatgcc cggtaaacgc gatataaacc tcttcatcag ccgctttttt 2181601 catgaccgca gccagtttag cagccctttg ttcatcttga ttctcaataa attgcttata 2181661 aagttccccg gttttatgca aaagctcttt tctgttttga tctgtcataa gtctgaaccc 2181721 ctttgtgccg tttcaattgt gaaccttttt cgaaagatct gaattcattc ccttttcatt 2181781 ttacacaaga ataaaccaaa tttctttagg agaatagaaa aaagccgcca ttacggcagc 2181841 ttctataaaa gaaaatctgc aacttttaca agttccagat tcatcaaaca gatttattag 2181901 agattccttt taatacaaaa ccaattaata cactatatgt acaaaccgct ccaagcaaaa 2181961 acagcattgt catttgcttc accatcctga ttgagaatct ttttcaaacc cattttaaca 2182021 tggttgagaa tgattttcaa tcgctatttt acgctgtatt cctgtaatgc tttgtcttct 2182081 gcgcgaattc tgacgcttaa caacacggca ttgaaaatgg aaaacagaca catggtgacg 2182141 tatgcttgat aaagcagcgg aatcagcaaa atttcgagga taacaacggc atagtttgga 2182201 tgtttcatcc atttatatgg accttttttt acaagctcta cacctggaac aacaaggatt 2182261 ttcgtattcc aatatgctcc taaggaacaa agcgcccaat accgtacgat ctgtacgctt 2182321 aaaatcactg cagcgatacc gagccaccag ctggacggct gtttattcat cagcagcacc 2182381 tcggcaatta aggacaggaa aaaaaggata tgcatcgtaa tgatatacgg atagtggctc 2182441 tcgccaaatt caattgctcc ttgcttcttt accttttgtt cgttttgcct ggccactgcc 2182501 atttctgctg ctctttgaac aatgagaatg gcgatcaaca accaaaacat gagtcaggcc 2182561 cccttttccc agctgaataa tagcaactct gatgagaaac ccggccctaa tgcgccaatc 2182621 agtcctcgtt cagcttcctt tttatgtccg ttctgcagat ggtctttgat cacatacaag 2182681 attgtggctg aagacatatt tccgtgcttt tgcaaaatgc tttgcgcaga tgaaagcttt 2182741 tctgacgaca gcccgagact tttgatgtat gcatcgatca ctttttttcc gcctggatgc 2182801 gccaaaaaaa cactgatatc atggaatgac agcttatgtt tgtccaaaaa aatctgtaca 2182861 tttgttttga gccatttttc caccaaggtc ggaatgtctc gtgagaaaat gactttgaat 2182921 ccttgatcgg taaagtccca gcccatgaca tcttctgatt gtttcatcaa aacagattgg 2182981 gcgtccatta tcttcggcgc aagcttcagc tttgacaccc tgcggtccgc cttctctccg 2183041 cataataaag ctgcggcaat gccgtcacca aaaagcgagg tgccgatcag attgcttttt 2183101 gttttatctt ccggctggaa tgtcaggctg cacagctcgg cagaaatgac aagcacaaaa 2183161 gcctcaggat acgctttgca gtattcggct gcacgcgcaa gtccgctggc tcctcctgca 2183221 cagccaagcc cccaaatcgg aatccgcttc gtatatggag aaaacggaag ttcattcata 2183281 agccgcgcct cgatactcgg tgtggaaaga cctgtactgg agacgaaaaa aacagcttcc 2183341 actttctcat aaggaatggc ttcttgaaaa aattccggat gagagaggca ctcacgaaca 2183401 gccgctctgc tgtgtttaag tgtttcttct atgtatattt gatttttttc ttcaaagctg 2183461 tgcccctctt tataccattc aatcggctta acaaactgtc tcgaatggat ttgcccgttt 2183521 ttaaaggagg ataacagcct gtcaatatcc ttaaaagaat gctgaaacat atagcgggcg 2183581 aactcggccg ctttctcttg gtttacatta tacgcaggaa gacttgttcc aatggataaa 2183641 ataaacgcca tgcgatcacc tctttgcata cattgtgccg caacaatctt ttttatatgc 2183701 aaaaaaaact ccgccgcggc ggagttagac tgctgttttt tgttcagcga ggtcagcttc 2183761 ttgttctatt tttttagctt tagaaaaaac gttatataca atatttaaga cgactgcagt 2183821 aaagctgccc gccacaatgc cattcgttgt aagcagcgtt aaggcactcg gaagctgttt 2183881 gaaaatatcc ggcacaacgg tcacaccgag ccccaatccc actgagcaag caacaatcag 2183941 cagattttcc tgtttcgcaa aatcaatgcg gctgagcatt ttaattccgt aagcaatcac 2184001 cattccaaac atcgccacca ttgcaccgcc caaaacagcg gatggaataa tagtcgtgaa 2184061 agcagcgatc tttggaaaca gcccaaatgc cattaggatc acacctgtga ccacaatgac 2184121 ggcatttttt ttgatccctg tgagctgaac aagcccgaca ttttgagaga atgccgtgta 2184181 aggaaaagcg ttaaaaatac cgcccagaag cacagccagt ccttcagctc gatagccttt 2184241 agacaaatct atctctgtca aacggcggtt tgtcaggtca cctaaagcaa agtaaacacc 2184301 agttgactcc acaaggctga caattgcaac gatggacatc gtaatgatag gcgctgcgtg 2184361 aaaagacggc gctccgaagt aaaatggctg aatcatttga acaactgccg cgtccgaaac 2184421 attatcaaat tgaacttttc ccataaaata tgcgatgaag gtgccaatca aaataccgat 2184481 caaaatcgag acggacttga taaagccttt tgtaaaacgg tatagaagca caatgatact 2184541 caacacggta aaagcaagtg caagattgga gagatctccg aaatctgcac ttccttctcc 2184601 gccggccatg ttattcatgg caaccggcat cagtgtaata ccgataatcg taacaacaga 2184661 gcctgtcacg accggcggaa aaaacgatac gagctttcca aagaaaaatg aaataagaat 2184721 gacaagaatg cctgaagcga taatgctgcc gtaaactgtt gaaaccccat attcagatcc 2184781 aatcgctatc atcggcgata cagctgtaaa ggtacagcca agcactaccg gaagcccgat 2184841 cccaaaaaat cggttgctcc acacttgcag aagtgtagcc acaccgcaca taaaaatatc 2184901 aatcgatact aagtaagtca gctgctcgac agtcagtccc attgcttttc cgacaatcag 2184961 aggaacgaca atggcgccgg catacatggc aagaacatgc tgaatcccta aagacagcgt 2185021 tttgccgaat ccatttctca tgaatgaacc tcctgtacga aggacacttt tccttcttct 2185081 aaagactgaa ttcttgccaa agattccact cggtagccca gttttacaag ttcatctctt 2185141 cccggctgaa atgacttttc aataacaatg ccgattcccg caatagaagc tcccgcttgc 2185201 ttcacaatcg acacaagccc gtgcgctgcc tgtccatttg ccaaaaaatc atcgataatc 2185261 agcacatgat cctgatccga caggtgggtc ccagacactg cgatttggct ttctgtttgc 2185321 ttcgtaaagg aataaacaga cgctgtcagc aagttgtcgg tgagtgttaa cgatttatgc 2185381 tttctcgcga agacaactgg cacacccagc ttcaagcccg tcattacagc gggagcgata 2185441 cctgatgatt cgattgtcac aattttggta ataccgtctt ttgcaaacct agacgcaaat 2185501 tcatcaccaa ttctctgcat aagcagcgga tcaatttggt gattcaaaaa agaatccact 2185561 ttcaatacct gatcagataa tacgacgcct tcttcctcta ttttccgttt cagtgcttcc 2185621 atcctgtcta cctccgttat gagaataaaa aaagcattgc ccgctcaaat aaagagcaag 2185681 caatgctgat atcacaaaaa accgtacacg tgcggttcca ttgctcaccc atagtcggac 2185741 atttacggtg cccggtagaa acttgcgtgc catatccacg cgattatatg agtgttccta 2185801 ttatattgta ataaattata tcaagattct aatctcttgc ataggctgaa aataaaaatt 2185861 cccgaacttt aattttgttt ttttagatat cattcgtatt tcaaggggat tcgatataaa 2185921 agagtctgac gaccgcgccg ccaggctttt gattataaca gatagagatt tgaatatttg 2185981 tttgataaat aatcaattaa atagcgaaca ttcagctctt ctcctgttgc atctttaata 2186041 atgtctaacg gctttttccg ttttccgtga atgtgcacct tttccgtcag ccattgcttt 2186101 atcggatgga actctcctct ttccaagaga gcgtcaaatt cagggagatc ctcaagcatt 2186161 ttttgtttca gctgagccgc atacatgtag ccgagcgcat aggatgggaa gtagccgaaa 2186221 tctccacctg cccaatggac gtcctgtaaa atcccctctg cgtcggtctg cggtgtaatc 2186281 cctaaataat cctggtattt ttgattccaa agcgacggca gatcttccac agacacttca 2186341 ttgctgaaaa tcgctttttc aatttcataa cggatgatga tatgaagagg atacgtcaat 2186401 tcatccgctt cgaccctgat aaatgaaggt tttgattcat tgattgcccg gacaaaatca 2186461 tccagggaga tgtccttgaa ctgtacaggt gatgcctctt gaatcttctt atagtacgga 2186521 gtccaaaaat gcttgttgcg gccgataaaa ttctcgtaaa ataatgattg cgattcatga 2186581 attcccatcg atgcgccgtc tgacaagttc gtgccactga gtgcttcatc aatattttgc 2186641 tcgtaaatcg cgtgcccgca ctcatgaatg gtcccaaaga tcgccgtccg gaaatctttt 2186701 tcatcatatc tcgtcgtgac ccgaacgtct ccccgattca gcgtagttgc aaacggatga 2186761 acggtttcat caagtcttcc gccatcaaaa tcgtagccaa gctcctgtaa aaaatacaga 2186821 ctgagctctt tttgcttttc tttcgggaac gcttttgtaa taaagcttgt atctggttta 2186881 tttccggaag ctgtcacctg tttaacaaga gggataatcg cttccttcag ctcagcaaac 2186941 aactgatcaa gcacctttac cgtgacgccg ggctcaaaca aatcaagcaa tgcatcataa 2187001 ggatgctctt gatatcccca atacgtaata aaacgtttat tgaattcaat cagctgttct 2187061 aaataaggag aaaacaagct gaaatcagat tttcctttcg cttcctccca cgctgtttct 2187121 gcctttgaac acagaatcac gtattctttg tattcagcct cagggatttt cttattctct 2187181 tcatactctt ttttcgccag ttccactgct tttttcgtat cttccgacaa gtcatcaaat 2187241 cgttcataca ggacatcgat aagctccttc attcgatctg atgtttggat attgaatata 2187301 tctgttgaaa gctggccgat actttcggca cgatcctctg agccattttt cggcgcgcct 2187361 gttctggagt cccagtgcat taacgcaact gcttcgctgt aatgtgagat tctttttaaa 2187421 agatcaaaaa attctttttc atatgtatgt atctccatat ccattccctc cctattctag 2187481 ccgttccatt acaggctaat ggaagggggt atgaaagtca aattgtttgt ataaaaggct 2187541 gccggtatgt tttgtggcag cctttttatt cagttgatcg tcatttgatt ttttggcgga 2187601 ggtgttctcc gctttttctg cttgattttt ttatctaccc acactgttgc cagcggggtt 2187661 aagagcgagg tgacaataac gcttgtcgcg ataattgcag ttgccgactc agcaactggc 2187721 gcaaatgagg cattcgcttc cgctaatgca tatggcacgg ctacagccgc ccctgccgta 2187781 gaagaagcgg ccactcccgc gacaccatct ccccgcgcaa taaaacgatc aagcaaaaac 2187841 aaagaactgc ccgataaaat gacgacagaa actccgataa aaatgccgag cagccctgat 2187901 tggatcagca ttccaaaatt caaggtattg ccgagcgaaa aggcgaaaaa tggaatgatc 2187961 gccggcacaa ccttgctgaa taagtctctg agatcatgat ccagatttcc aagtatacat 2188021 ccaagtaaaa acgggatgac tgtcgctgcc agcgtttccc atgggaatgc ggcaagtccc 2188081 gtcacaccaa acgtcaccat ggtcataaaa ggaccagatt ctgtactgat aaaggcgaaa 2188141 gcgcccgcat cctcttttct tcccatgtga ttcatgagcg ccaaatacag tccgccgttc 2188201 gtttcattca ttaccgcgac aattgctaaa acagaaaggc ctgcaaaaaa gccggattgt 2188261 atgccatcgt caggtataaa ttgcgctgcg atcacgccga gcagcgccgc aaatccgatc 2188321 ttccccaata ataacgtgat tccttttctt gcgatatagc ctgaagaacg aaaatcaatc 2188381 gttgctccta cgcaaaagat aaaaacaccc agtatcggca gcgttccggt aatcaaagca 2188441 cccgtaaacc ctccaaagaa ctccgctgtt ccaggcgcaa acgtgttgag cgccgctcca 2188501 agaaatagcg gaataatcat cattccgcca ggtacccgtt caattgtcgc cttgattttc 2188561 atattgtgga ttctcccatc ctccggttat gaaaaaacaa ttccacttac acttggaaaa 2188621 cagcctgcaa atcctctttt gaacagctgc ccaactggct gccgactccg acggcgccag 2188681 ctccggctct aagccaatca ggcacttcag acggatgtat cccgcctgtc ggaataaagg 2188741 tcacctgcgg gaaaggaccc gctaaatttt tcataaacgg aatgccaaac acaccgcttg 2188801 ggaacagctt taatgtcgta aaaccgaatg tcagcgcttc cataatttcg ctcggagtca 2188861 agacgccggg gatataatgt gtctttacaa aagatagatg ttcagcaaga tcagctgaaa 2188921 aacccggact gacaataaac tgcgcgccag ccttagcagc ttccccagct tgctgcgcgc 2188981 tgatgaccgt acccgcgcca attaaaatat cttccctatt acggaaggat tcgataatat 2189041 ctgatgcccc gggggtcgta tacgtcactt caactgcacg aatcccttta tctaataaac 2189101 tctcaatctg ctgacaggcc tcctgcttat cctttgaacg aatgactgca atcagctttg 2189161 cttctttcag acggttttca acgactttgg actccatatt aataatcccc tttcttttgg 2189221 tgaaccgttc tttgagcaga taaaaaagaa gctaatttct ccctggtcgg caaaccgtcc 2189281 atatcccccg gtgcctgcac ttgcaaagcg ccaatcgcat ttcccctttg caccgcatcc 2189341 ttgtacgaca aaccgtctag gataccgctg attacaccga ctgcaaatcc gtctccggcg 2189401 ccgaccgtat caaccacccg gtcgacccgg cagccttcta gaaatccttc acttgtcccc 2189461 gttttaaagt aagcgccttc ttttccaagt ttaatagcaa caaagctggc accttttttc 2189521 aaataatagt cggcaatgcc ttcaggtgtt ttttctccgg tcaatagctc tccctctgcg 2189581 atacccggga aaaaccagtc tgcaagccca gccagatcat tgattgtgtg taccattgtt 2189641 gcttgatcag gccaaagcga aggtcttaca ttagggtcga atgaaatggt cttccctgcg 2189701 tttctcatgt cgttcatgac atgatacgtg aagtctttca tctcggctga taaagcaggc 2189761 ggaatacctg tcacatgcaa atggcctgcg cattgaaaat aatctctcgg atattcagct 2189821 gtagttaatg tgcttgcagc tgagtttttc ctatagtagg taacttgcgg gtcgccttct 2189881 ttcacttttg acttcagcag cagcccggtg ggattttcgt cctgcgagcg gatcacgcgg 2189941 gacacatcca ctccctcttt tttaagctct tgtaaaataa acgttccgag ctgatcattg 2190001 ccgaccttgc tcatccatcc cattcgaaat ccgagtctgg caaggccgca ggcgacattg 2190061 ctttctgctc cggcaagccc tttagaaaaa gtggatactt catgaaggcc tccatactca 2190121 tttgcataaa acatggccat tgattccccg aatgtcaccg catcaagctt catctcttcc 2190181 caacctcctc ttagttgagg gcacctagga ttaaagtgac tttctcatga tgacttttgc 2190241 ctctaattca atggtttgag gcgctccttt gtcaccttca atccttttta atacacgttc 2190301 catcgccgtc ctgcccatat catgtgacgg ctgggcgatc gttgtaatgc ctggaccgat 2190361 cagtttgtac cactccgtat catcgaatcc tgcaatccct atatcttgag ggatgcgcag 2190421 gccaagctct tccatacagc tgatgatttt cagcataatc aagccattca aagccagaat 2190481 cgcttttttt tgctccggca tttccttgtg aaaagaacga agctccgcct taagctgctc 2190541 cttgtccttt acgtcaattt catgcaatct gacaagcccg ttcacatttt gaaccgaagc 2190601 catttcctga tacacagctg ctctttctgc acgagggctg atagaggaaa tcggttcggt 2190661 aaacagcgcg acatcagtat accctttgct gtacaccttc tgaagaatct cttttgtgat 2190721 ccatctgttg tcagtcgtta cggtatccag tttcagatcc ggcagtttcc ggtcaattaa 2190781 gattgttgga atttgctgtt cagcaaaagc gcggagtaca tccttgtttt cccctgttgc 2190841 gtttaaaatc aagccctcaa ccgaatgggc ttctagcttt aagagcattt cccgctcttt 2190901 ttcaggactg ttatctgtgt tgcacaccat aatgctgtat ccatattgat cacaaacctc 2190961 ttcgactccc ctgaaagcag cgaccgaaaa aggatttgta atgtcagcca caacaaatcc 2191021 gattaacttg ctttttttta ttttcaaacc ttgtgccatt ttactcggcc gataattcaa 2191081 ttctgcgatt gcctttttaa tgtttttcac tttttcagga gaaatcgcgt caatttttcc 2191141 gttaatatag cgggaaactg tcgatttcga aactcctgca cattcagcta cgtctttgat 2191201 ggttgtatgg cctgttgttt tctttttcat tcaagtgctc ctgtatctca tatatttgaa 2191261 accgatttca aaaccgttac aacaaaagaa taccataatt ttaaaatttg ggaagagttt 2191321 ttttaataat atgtcaattc attatttttt cgttgactct tttcactatt tatcctaaaa 2191381 ttttctttga aaccgttacc aaaatatttt cattcaagtg atgctgaaat cctaaccaag 2191441 ggggaaatat aatggaaaat cgttattctg tacatcctga acaagtaaaa cgctttacaa 2191501 cagaggagct tcgcagtcat ttcttaatgg attctttatt tacagaaaac aaacttacga 2191561 tgtattactc acatgaagac cgggttgtca tcggcggagc ggctccaggg caaagtgaac 2191621 tgaagcttga tgcaggtgat tttctaaaaa cagacttctt tttggaacgg cgtgaaatcg 2191681 ggattattaa tgtcggccag cctggtgccg ttagagtcgg cgatgatgaa tatgtgcttc 2191741 aaacaaagga ttttctctat attggaatgg gcaatcagga tgtatcgttt tcaagcctga 2191801 acggggaaaa agcgaagttt tacttcgtct ccgcttgcgc ccacaaaagc tatccgacac 2191861 aaaaagccgc cctatctgaa ctgacaccgg accgccttgg tgatgatgca gcgtctaatg 2191921 tcagaagtct gtacaaagtc attcatcagg atggcattaa aagctgtcag ctgatgatgg 2191981 gaataacgat gttagatcaa aacaacaact ggaataccat gccagcacac gttcatgacc 2192041 gtcggatgga ggcttatctt tatctggatc ttgaaaagga ctcaaaggta tttcatttca 2192101 tgggccagcc ggacgaaaca cgccatcttg ttgttggaaa tgagcaggct gtcctttctc 2192161 ccgcttggtc tattcattct ggcgcaggaa catcaaacta tagctttgtg tgggcgatgg 2192221 ctggagaaaa ttacacattt acggacatgg atctcattcc aatggatggg ctgaaataag 2192281 atgggttatc tacatgacgc cttttcatta aaaggaaaaa cagcgctggt gacaggcccg 2192341 ggaacaggga tcggtcaagg aatagccaaa gccctagccg gggctggcgc tgatattatc 2192401 ggcacatcac atacaagcag tctgtctgaa acacagcagc ttgtggaaca ggaaggccgg 2192461 atatttacat cttttacatt ggacatgagc aagccggaag cgataaagga ttctgcagct 2192521 gagctgtttg aaaacaggca gatcgacatc cttgtcaata atgccggcat tattcatcgg 2192581 gaaaaagcgg aagattttcc agaagagaac tggcagcacg tactgaatgt caatctaaac 2192641 agcctgttta ttctgacaca gcttgctggc aggcacatgc tgaaaagagg tcatggaaag 2192701 attattaata ttgcctctct cctgtctttt caaggcggca tcctcgttcc ggcttacacc 2192761 gcgagcaaac acgctgttgc cggtttgaca aaatcatttg caaatgagtg ggcagcgtca 2192821 ggtattcagg tcaacgcaat cgccccaggc tatatttcta ctgcgaatac aaagcctatt 2192881 cgggatgacg aaaagcgaaa tgaggacatt ttaaagagaa ttcctgccgg ccgctggggc 2192941 caagcggatg atatcggggg gactgcagtc tttttggcat cacgtgcttc agattatgta 2193001 aatggacata ttttagcagt tgatggcggc tggctatccc gctgacaaat aaaaaagctg 2193061 acgaacgatc gtcagctttt ttccattaca tcatgtgcgg ttcaacaggc aagacctttt 2193121 tgacctcatc aatgatgcgt tcattttctc cgccagcgta aatgtgaatc gagccgctgt 2193181 cttgattcga gcgaatcagg cgcccgatgc cctgccgtac acgtaacaac atatatggca 2193241 gatcaacttc ttcgaacgga tcttttttcg ctccgttgcg cttcgctgta aatacaggat 2193301 cgtgtggcgg gaacggtaat gaccaaatgg taacattctt caatgcgtca ccgggaatgt 2193361 cgagtccttc ccataagtga actgaacaaa gtactgtttc ttcttcctct tggaatttct 2193421 ctactaagct gctgatttcc tcatcacctt cgaagaaaat tggatacggc agctcccatg 2193481 ccgccgacag ctctttaaac tcgtttaatt cttcaaaaga agggaaaagc accagcgttc 2193541 ttcctttgta tcgtttgatt gtttcaatcg tttcagccgt tttttgttca gcgtccatat 2193601 ctgtttttgc gtatagatta atactcattt gctcgtcata atcataaggg gaatcaacag 2193661 ttaatgacaa ataatcatga atcccaagac tgtcggcaat ataatcaaac gaaccgcctt 2193721 ctgacagcgt agcagaagaa aagatataag gaattttctt agaaaacact ttttcgccaa 2193781 gtacttctgc taccgttctc ggcatcacga caaaggttga ttctgcttcc tttttctcca 2193841 gccagctgat cgcatccttt tgatatagag ataatgaata cgccatttgt tcaacatatt 2193901 cttccactac tgacagttcg tattgatcaa tcgtatacat ttcagactca aatacaagtg 2193961 cctcaccgat tttatcaagt aaacggcaaa gctcgtccgc cgcctttttg acacgatggt 2194021 cattttttat ttctaaacgg tgtgaaccgg ctacttcctt tgattcttca gaaagaacat 2194081 agaaaaattc gtcgtttgcg agaagcgcat cttcaatcaa ttctgcaaac tcttctctga 2194141 tgtcattttg cagcaatcgt tctaaaaaca attcaagagt agactgcttc actctatagg 2194201 ttagcgcttt ttgcgcagca aactctaaca agtgcccctc atcaaataca actgcactat 2194261 gatcaggcaa gagcggcagc tggccctctc gtttgcgtga ttcttccgtc cacacatgct 2194321 ccatataaaa atcatgggaa caaatgatta agtccgttga cttgcggtag taatctctgg 2194381 aaagtgtcag accgcatctg tgtctcatat cacaagtcag acagtcctga aacgagtcgt 2194441 agcttacgtc agaccactct tcattcgata gatttgcgta ctgcttacgg tcgccatacg 2194501 gataaaagcg ctgcatcgcc tgggactcgt ggacaaatga cggtaacgac tcataaagat 2194561 ccagccattt atcatcatca gaacgctgca ttgttttttc aagcttcttc aagcataaat 2194621 attgctcatg tgattttgac agccttgtat caattttcag atcaagatgc tcagccagct 2194681 tagaaatatc gccctctttt ttcaccagct gttcaattaa tgtttcatcc gcacaagcga 2194741 tgatggcagg tttgccgaca taccttgcat agctgattgc aaaaagaaga tataccagcg 2194801 ttttccccgt tcccactcca gcttcggcga acatgacttt tttctcttta aacgcccgct 2194861 ccagctgaaa agccataaat acttgctcgt cccgaagatc aaaccctttt tcgggaagga 2194921 tatcgtaaaa cacgtcacca atccaattgt tcaattcttc ataaaaattc tttgttttcg 2194981 ttaaagaaaa aggcaaacgt gatgttgtca cctagttcca acccccaact attcgacatt 2195041 cagaccacca ataatatcat tttccgctga tgaatacaat aaaaaacttg gcaatgccaa 2195101 gttttttgca gtttacttac gattgatcac atgcgacgat aaaaaaggat ggtctgttga 2195161 ataaatatgt tctaccgctt tttctaaatc agtttgcgca tgcgaaatca cagacggaga 2195221 cgaatcagtc ccgagctcct tcagctcgtt tgctgttgcg tcaagcgccc tttgaataag 2195281 attaaaatgt tcgctgttca gcatgagatc acctctgatg gaaataatca tcattgtatg 2195341 cgaacttttc attttatata catgctttac cgcatgttat caccgaaaca tgcacaaact 2195401 acacttgata ttccgtctcc ggattatccg tcttatcaac aatattctat cagggagtga 2195461 tgttgacatg agttatagaa accgattaga tcagcattct gaactgtttc atcacaattg 2195521 gacgcggcct aaacgttcaa agtctcaagt aaacggtcac actgaaatgt cccaaaccaa 2195581 cattatattg agaagcaacg cgaaagctca ccgttggtaa cgatagaata gggctgaaag 2195641 atgaaagaag acgcatgcag agcgtcttct ttttatgcgt tttctgtttt cttgcgctgc 2195701 ggtcttactt ttgaccagta ttgataataa tccgttttaa taaacccgtt aaagagtttt 2195761 cgtttcttcg ttgcttttct gccatatgct tcctcaaagt tttcatttga tgtcagcata 2195821 tacacagacc aagtatcaag cggctcgaac gcctgcccca tttctttgta catctgctca 2195881 acggcttttt tctcgccgag acgctctcca tatggcgggt tgccgacaat tacgccaaat 2195941 tccagatttg tggtaaagtc tttgacctgc atctgtttga actggattag atctcccaat 2196001 cctgcttcct ctgcattttc ttttgcgatt tgaaccatgc ggtggtctat gtcgctagcg 2196061 aaaattgtaa gcggctgatc ataatttgcc ttttcttcga cttcaagccg cgctttgttc 2196121 cacagatctt taccgatcca ttcccaatcc tctgatacaa aatcgcggtt gaatcccggg 2196181 gcgatgtttt ggccgattag cgccgcttct atcgcgattg ttccggagcc gcagaaagga 2196241 tcaacaaacg ggcggtcagg cgtccaattg gttaattgca ccaaagcggc agcaagtgtt 2196301 tctttaatcg gcgcaccgcc ctgatcgaca cggtatcctc gtttgtgaag gcccgtccct 2196361 gatgagtcca gtgtaatcaa agcctgatct ttcaataaag atatttccac tttatactca 2196421 gcacctgttt cttcaatcca atcattggct ttgccggact gcagcttgag cttttcgaca 2196481 attgcttttt tgacgatccg ctgacagtca ggaacgcttg caagtgttga ttttaccgat 2196541 tttccgatga cagggaattt cccgttttca ggtataaatg agcgccagtt aatcgctttc 2196601 gttttttcaa acagttcatc aaatgttttc gctttaaaag aagcaacctg aacctttatg 2196661 cggtcggctg ttctaagcca aaggttcgca cggcagatgg caagtgcatc accttcaaaa 2196721 ataactttcc cgttatcaac cttgcattcg tatcctaaat ctcgtacttc ctttgcgaca 2196781 acagcttcaa tgcccatcgg cgccgttgca attagtgtat acttcttcat cgtatcaccc 2196841 tgtcttttaa aacttttctc ttttcaagat aaaagctctc cttatacggg agagcttgtt 2196901 ttcatcattt taaatgtaag tggtctaacg ttctgtaagc catgttttgt tccatcgtac 2196961 tgcaaacggc tcatcacctc gtactcaggc ggcaatcatc tatctacaga aagcattctg 2197021 tccttctctc cgttgaattc cgttaagaag gttcccctac caaaatttgg gtttctcgct 2197081 cgaggggttt accgcgttcc actctcacca tttctagtga gacttcgtca ctgtggcact 2197141 ttcaaggata ctcagccata tccgaagacg taggcttttt tcctgccgtc agcctctaaa 2197201 gactgcccta gcttatgact tcgctaggca cgaacactac gggcatctca gcaccgtgcg 2197261 agcatggact ttcctctaca gattcaagat ctgcagcgat tacccgaacg ttaagaacat 2197321 gaattattat ataacaactg attacaattt acaagcgcca tttttttcaa gcgtgatcaa 2197381 tcataaagct tgctgccaaa aacgtgtttt tctaagttag acagccgttt taaaatatca 2197441 aagtttgttg tgttagattg cacaggctgt tttttgctgg cttcttcaag ctgttttttc 2197501 agctgcagat tttcctgctg cagttcttca atttcttgat ggaaggtttc ataatcctta 2197561 ataatcatat ctaaaaattt gtcaacgtct tcttgcttgt agcctctaac gcctgtttta 2197621 aattcttttt ccaaaatttc tttcgcagaa agctttactt tatcagcaag catctttttc 2197681 acctcgtatc gtgaatcatc acatatattt tttcagaaat ctgtacggtt gtcaaatttc 2197741 tctctcattg ttagtagctg tcttcctcca ctgtcactct caagtcatcc attgtaataa 2197801 agtagatggg atagccatcc tgttcgcgcc ttttttccgc tgtcccaagc atatacttag 2197861 gggagccttc cttttccggg tcatataaaa gcagaagccc gtcggactta tcaatgaaga 2197921 actgattttt ttgtttgaat tgaagcgggc tttcataagg acggtgagtc aggcttgctt 2197981 catagtctgc ctgagccaga actgcttcat actgttcttt attcggttct ttccagttct 2198041 tttcctgctc gtaaaatggt gtgatgacag ctacctttaa gtcagggtat tcctcctgca 2198101 aatcatatgc agcttctgcc gcccacagct caactccaag ctggcccgaa attaaaatcc 2198161 attctaatcc ttcatccaaa aaagcaatca gccggttttt aatggctttt tttatgtaat 2198221 acagcgcctt gtcatcctgc ttaaatatcc ccagttcaaa cggtttatag cccgttattg 2198281 ccaatacttt catcatttca cctgctttaa aaaatggggc tcccgtgggc cccatttgtt 2198341 gtgctgcatt gtttacacca tcaagctgca cgttttccat actagtagtc gcagcaaggt 2198401 tttcctgctt gaaaatgctg atgcgtagcc gggtcaacat ttgagaaagt gtgtggaaag 2198461 tagtgaacgt gctgaaaatg ctggtggttt acgtttgttg tatgctgtgg gtgaatgtgc 2198521 ggcacgatag tcttcgaaaa cgtatggtgt tcacagcaat gagtaggatg gacaattggc 2198581 gccatcatat gcggtctgca gtgatgcatg ataaaatccc ctttccataa actttattac 2198641 aatactaagt tatgaaaaat aaggggtaca tgttctgatg caaagaccta ttttaaaagt 2198701 gtgcaattaa gctgtcttta aagtttgaaa acacaaaagc aatcaaaaat accacaacaa 2198761 agaacaagta aaaaacaccc ttatacatac caactctccc tttaaaaata actaacgtca 2198821 ttttacagga ttcgccgcta ttctacaaca aaatcaatgt gaattcagca aaaaaaattc 2198881 atggcgaaac aagtcgtctt ttgcgctttc ccggggaata tttaagagga atatttcctc 2198941 tttagccggg caattctcac atgcagtttt tcagtttctt tctctgataa gcatgccgca 2199001 tcgctaagcg attgctctgc tacttgcaat gcttttccga attctttttt cttatgctca 2199061 aaatatttcg cgagctctat tacagcagcg tatctgcact tctggttttg cgagcgggac 2199121 agcttttccc aaagcggcac tgcttcttcc aagcggtttt gttttttgta caggagcgat 2199181 aaatccagcc gtgcactgtc ctggtcctca aacgattttt ctataagcct ttccaactgc 2199241 ttgatcgctt ggtccgtttc tttatgagcc ataaaccatt tcgccatagc ataggcttca 2199301 ctgtgttctt ttggcgcatg tgattctgaa aggatttttt tagacatatg gatgtacaat 2199361 gaaatgagtg ataacacatc catttcatta tgatgcagga caccttttaa aagatccggc 2199421 tcttgcgcct tgataaaatg aaagtaaagc attggcgcca agtagcccgg tgtgtcttct 2199481 agcctgcgga tgccgagctc ctctttttca accgtgccaa gagatacacg gtccattttg 2199541 tgtttccaca ggcgtctagc tccatgcaaa agatcaaagt ggccaaactc cggaagcttc 2199601 ggaagtctgt cacggatcaa ggtgtgcctt gttttcacct gcggccaatc aaaggctttg 2199661 ccgttgtagg tcacaagtga tgtaatgtca acctcgctta aaaagctttg gtacaaggcg 2199721 acttcgttcc ccggtttggg caaaagatgc tgtttgactg tcactcggtc ttcatatact 2199781 ctcgcatgcc caagcaaaaa aatggtattc ccagctccac ccccaagacc ggttgtttct 2199841 gtatcaaaga aaaagaggtt gtttttgtta tacccttttg ctgacaatgt atgcgacagg 2199901 ccgctttgat tccacagtgt gatcacttcc tcaagctcag aaaagctgta taacccatgg 2199961 cggtgagaaa gcggatattc tacttctctg atgaggcaat attcatcttc gaagatgaaa 2200021 ggcttcatgc caaaagcctc ccactcttct aaaaacggga tgtcatcaaa gtggttttct 2200081 tgtttgcctg cttctatttt ttgttctcct tcgtcgagcg ccatgtgctt tttcatccgt 2200141 tggagtttcc cttttaatga catatccggc ctccctcctt acgacatttg atccaacagc 2200201 tgcaaaattc tttcctttgc ttttatccct tctatttccg tacctataca agacggacag 2200261 ccgtcatgac aaggacaatg tgtaatcagt tgtttcgccg cttcattaat gtctgaaaaa 2200321 cgtttaaaga cttcctccgc caaaccgata ccgcccggat aatgatcata taaaaatatg 2200381 gttggcaatc cggtatgggc tgctttaatt tgagaaacaa catgaacatc atttcgatca 2200441 cacatgatat acacagggac aatatgctgc agcacattcg agatgccaag aagcagctgt 2200501 tccagtgtct tttccccgat gtcttcatcc gctgttttga tttcgagcca agctgcactt 2200561 gtatgcagtt cttcttccgg caaatgaata ggtccagacc caatattttc aaaagtggtc 2200621 atttttattt ttttaaaaat ggtcggcagg gcattgacag tgacgtctcc gtagtgcaat 2200681 gacgtacggc ttttttcttt cgttttatcg atttctaata ccttcagctg aactgccagg 2200741 tttgcatccg tataatattc gacatcgact tttctgacat acgccttttt atggtcccaa 2200801 tcgagcttct caacttgata ctgaacgcct tcatgcaaat aaatcgcttc atcatgcaaa 2200861 agcgtcatcg cactaaaacg gtccatttca ccgataatcc ttacatttgc aatatccgac 2200921 tgatcaacta taacgacatt ttcctgggag gcggaacgca aactgatgtt tgacgcaggg 2200981 aacgactcac ttgcccaatg gtaccgttcg ccgttgcggt gaagaacagc ctcttcctga 2201041 agatactcaa gaatatcact gacttccatg gctccaaatt cttcatcagc tctaaaagga 2201101 agctcataag ccgcacactt taagtggtct actaaaataa tcaaattctc cggattgatt 2201161 cttgcagatt ccggcgaacg attaaagaaa tattcaggat gccgcacaat atattggtca 2201221 atcggtgttg aattggctac catgataatc aaagattcac cgtgtcttct gccggctcgt 2201281 cccgcctgct gccaagcact tgcaacactt ccgggatacc ccgtcattac acacacttgc 2201341 agctggccga tatcaacacc aagctctaag gcattcgtac tgaccactcc taaaatgtcg 2201401 ccttctctca gtcctctttc gatttctctt cgctctttcg gcagatagcc tccccgatag 2201461 cctctgattg attttgttcc aatctctttt ttcacaagct cctgaatatg gcttaaaata 2201521 atttccaccc gaactctgct tctggcaaaa acaatggtct gcactttgtt tttaaggaac 2201581 tctttcgcca gttcattcac ttctgcggtt gcgctccttc taatattcag cggtttgttc 2201641 acaattggcg gattgtaaaa cacaaaatgc ttgcgtccgc tcggtgcgcc gttgtcatcg 2201701 accagccgca tcggtttgcc tgtcagctgc tctcccaatt cctttgggtt ggcaatcgtt 2201761 gcggaagtac aaataaaaac tggatcactt ccataaaacc ggcagatccg cttcagccgc 2201821 cggatcacat ttgccacatg gctgccgaac acacctcgat acgtatgaag ctcatcgatg 2201881 acgatatact taaggttttc aaacaaactg acccatttcg tatgatgcgg tagaatggca 2201941 gaatgcagca tatcggggtt tgtaatgaca atatgacctg cttttctcac cttttgtctg 2202001 attgccggag acgtatcccc gtcatatgta aagcttttaa tatcaatgcc catttcatca 2202061 ataatttcat ttagctcgct cttttggtct tgtgccagcg ctttagtcgg aaataaatat 2202121 aacgcccggt ttgtttcatc ttgggcgatg gactgcagga ctgggaggtt gtagcataac 2202181 gtttttcctg atgctgttgg cgttacggta acgatgctct ctcctttttg cacatattga 2202241 aaagcggaat attggtgagt atatagttca tcaatgcccc ttttcgaaag ggccgctttg 2202301 attctctcgt ctatactttc gggcataggc cttgtttttg cttcccgagg ctcaatttca 2202361 tgccaattca caacgttttc atttcctttt aaatcagaaa tgagttcagt cagtgatttc 2202421 tttttcattc tttacacctc tttgtcaagt acagtttacc gaatatttgt ttgcatggct 2202481 aggtgcaaat tttatacagt tgaataaaaa aagcaaggca tacgccctgc ttatttcgct 2202541 tttattgtaa agagctttga ttcgccttta cgagcagcct tttcgcctgc cgataccatt 2202601 gatcctacag cctcaccatt cattataacg attgggatga ctgtgctgct cgctttttct 2202661 tttattaatt ccaaatcaca tgtaatcagc gggtcaccga ccttcacttt atccccttct 2202721 ttaatgtggg cagtaaatcc ttctccgttc atattgactg tctccagccc gacatgaatt 2202781 aacagctcaa ttcccgagcg agtccgaatg ccaacggcgt gtttggtgtg gaaaatctga 2202841 atgacttcac cttcagcggg agaaacgatt tcaccgctag aaggttccac cgctattcct 2202901 tctcccatca ttttctgtga aaaaacaggg tccggtacat ctgacaggtc cattactgta 2202961 ccgtctgccg gagaataaat aacctcttct gtcacctttt cctgaatttt gcccattccg 2203021 aataattttt tcagcaatgt attttctccc ttctcattca cttcaaccgt tatcccttca 2203081 ttcaccacta tttaaccaca ctttcaattt tgcttcaatt tataacaaca tctggcatag 2203141 acgcataatc tggttaaaaa aggcggtggc gatattggaa ttccatgatg acaaaaagaa 2203201 cgaactgcaa aagaaagaag aaatcataac ggaggcaatc gacactcttt ttcaatcctc 2203261 agcgttcggc aaccttataa acggatttca gaacctaatc aactcgagtt taaaggatgt 2203321 gcagacgacc atacatgtca gagaaagaga tactgggctg tatatcgata ttaccattcc 2203381 ggcgacgttt cgagatggcg agatcgtcgt tgatgttaaa tcgaggtatc tccatgtaac 2203441 actccaagaa aaacagaaac accaaaatga ggctaccttt acaagcatga caagaacggt 2203501 tcagctgcct tatgaagttc gccaagaaga tatggaaacg tcttggaacg agcagacaat 2203561 gacacttttc tttccaaaaa ataagcatga atgaacgatt cattcatgct tctatcattt 2203621 aaaaaagctg gtaaatccct ttattaaaga tccgacctga ttcattgcac tcattacttg 2203681 acctgtcgta tccatcattt tattaaaatc aaattgccca ttggcttttt tgaactgcga 2203741 cataatgctt tgaaattgtg aaggctgctg ttgattaggc cttgggatag gataagggtt 2203801 agaaaataca ggcggctgca taggcatagg ctggatcgga gcataaggct gataataatc 2203861 ctgctgtcca taatgctgct gaggcagttg ttgctctaaa taaccgggtg cagcctgctg 2203921 ataatatcct tgcatatgct gaggataata atagcccatt tgccgaggat agcttcgaga 2203981 gctcccgttc attgcgattc ccccctaaac acaacatatt tctcttctat atatgtatga 2204041 atgacttcta ttgtttgtgt cacaagtgat gattagcatt tgtcaaattg tgtcgaaagt 2204101 ttaaattttt taaaaacaga aaaaagtcga atcattatgg taccatattt tcaatacaga 2204161 tgagagggga tgcaccataa tgaacgtatc atacttaagc aaacgttttg cagaaatgaa 2204221 gaaatatgaa acagactgta tgaataaact gatggacttt gccaagttcc tctatattca 2204281 aggacatctc agcataactg agtttcgtaa cagtatgaag gttctcgaag caaatggagc 2204341 agaaagcccg gcatatgaga tgaattaacg tccggccccc tataaaaacg aaaagaagac 2204401 agccttttac cggctgtctt ctcttgcaat ttcatccttt actgcgtgca atgtataaag 2204461 gactgactca gtgatgtcct tgaatcgttt tttatgaata tgatgaacat aagattgaag 2204521 gaccaattcc aggaaattat cctttacggc ctcaatttgc tctttatgca catattttgg 2204581 ccggcggact tttatcaatt caagagcacc ctctgcccag cgagcagcca gttcatcatt 2204641 ctcttcaact gcaggcttta tcgtctcaaa aaaatcataa gaatgattac tgttttttcc 2204701 ttcctgatac cgatcagcgc ctttttcagc aacttcaatc atttgctcgg tcatttccag 2204761 caaagtttgt gatagcaata tctttcacct caatgcctat cgtaccaaat ttcactcaca 2204821 aattcagccg atgcggtata ccttctcaaa cgcatacctg tgttcaggcg attgatacag 2204881 ctcatttata caaatatgaa gatctatgat ttcttcttcg agcacactta ggcgatcgtt 2204941 ctccgtttcc cgcatctcag cctctaatgc atttacagaa tgattcaggc tttgctcagc 2205001 tcgcgttaat tcatcttcta tatcagaaag catacggaga atatctgtct tgcatacata 2205061 accggacatt cgtgtacctc cctttccttg tctctcccgg ttaacattct ttgctctcaa 2205121 ggctctttcc ttcctcatga caaaactaga agcaaatcgc caaacaaaca ggtattccac 2205181 gaaaagctga agttttcgac aaaaacaccc gcaaaaattg tatgatcctc ctcattaatg 2205241 caaacgatac ttgtgaggag gtgccgtatg aaaacaagac cgaaaaaagc cggccagcaa 2205301 aaaaagactg aatcaaaggc aatcgattct ttagataaaa aattaggcgg cccgaaccgc 2205361 ccttctacgt aagaagcaag gaatttcctt gcttctttat tttttcagcc actgctccac 2205421 cgcaaaaagc gcatgaagct ggcgcttttt atgtaaatac cagtctgtca attcaatctg 2205481 cttcggcaat tcctcgcgcc taaagaacgt tttctttatc tttccatgaa accaatctgt 2205541 tttcgttccg tctaatgagt ggattaactc agggtagcat gtccttagca taggagatgt 2205601 tctttttgta atcccgatca tcttttccat atcaaaacgg gaacctgtgt gcggcactgt 2205661 gtgcaaaaag tgataaaaag aggagaacaa ttctggcttg aacagcaatt gagacagctg 2205721 ctttcccagc cttatccttt cctccgcctt tgaaaagcgt ttcactgaaa tgccgtaaaa 2205781 aaacccattt gaggaaggaa aaataacggt gttaaaatga aaccagtcac ttaaataaaa 2205841 aggaatcgtg tcaaaaacat tctttttaaa cgaaggattt tgtataatag gtgtttggat 2205901 agtgttttgt tcatttataa tgagggcata cattagccgc tccgtatttc gctcatgcca 2205961 aaaacgggtc cattcttccg acataaattg tgagacgcca aacacatgca gcagatgaaa 2206021 cagcggtttc ccaactcttt ttgaccagtg gtataaaaga agctgcggat aggcatccga 2206081 aaaaataagc cagttcgctc tttcataggc taaaaagaac catttttgct gtctctcacg 2206141 gagtccaagc tgaaacagac tgccttttaa gtcagtcatt gaccagccgg cattacgaga 2206201 aacgaaagaa gccaaaagcg accatttgat ttccggatga cggtcgtaaa atgctttata 2206261 agcatttgtt cttgaaatgt tatccgcgtt tttcattttt gtctgccgct caatccggct 2206321 cagaagcttt ctgatggcct gttgttcttg cacgttcatt cacttccgtc atgattagtt 2206381 taataaggag gatgagaaag tgattcggta tcctaatgga aaaacatttc agccgaaaca 2206441 ttcggtttca tcccaaaaca gtcagaaaag ggccccgtct tacagtaatc gcggaatgac 2206501 cctcgaagat gacttaaacg aaacgaataa gtattatctg acaaaccaaa ttgccgttat 2206561 acacaaaaag ccgacacctg ttcaaattgt aaatgtccat tatccaaaaa gaagtgccgc 2206621 agtgattaaa gaagcttact ttaaacaatc atcgacaaca gactacaatg ggatttacaa 2206681 agggcggtat attgattttg aggcgaaaga aacgaaaaac aagacctctt tccccctgca 2206741 gaattttcat gaccatcaaa tcgagcatat gaagcaggta aaggctcaag acggtatttg 2206801 ttttgttatt atatccgctt tcgaccaggt ttattttttg gaagccgata agctgtttta 2206861 tttctgggac agaaaagaaa aaaacggcag aaaatcaatt cgaaaagatg agttggaaga 2206921 aacagcttat ccgatttctc ttggatacgc acccagaatt gattatatta gtattattga 2206981 acagctttat ttttcgccat catctggtgc gaaaggttga ttaacgaaag gttgagatgt 2207041 tatgtcagat caatttaaca gccgtgaagc tcgacgaaaa gcgaacagca aatcgagtcc 2207101 ttcaccgaaa aaaggcaaga aacgaaaaaa gggcggattg tttaaaaaga cccttttcac 2207161 tttactcatt ctgtttgttt taggcgtagt cggcggtgct gttacatttg ccgtcatggt 2207221 ttctgatgcg ccgtcccttg atgaaagcaa attgaagacg ccttattcat caacgattta 2207281 tgataaaaat ggaaaagaga tcgccgaagt cggcgccgaa aaacggacct acgtctcgat 2207341 agatgaaatt cccgatgttg taaaagaagc ctttatcgcg acagaagacg ctcgttttta 2207401 tgagcaccac gggattgacc ctgtccgtat cggcggtgca ttagttgcca actttaaaga 2207461 cggcttcggg gctgaaggcg gaagtacgat cacccagcag gtcgtcaaaa actcccttct 2207521 ttcacatcag aagacgttga aacggaaggt gcaggaagta tggctttcga ttcagctgga 2207581 gcgcaattac tctaaagatg aaattttaga aatgtattta aaccggattt atttttctcc 2207641 tagagcatac ggaatcggaa aagcggcgga agaatttttc ggcgttactg atttaagcaa 2207701 attgactgtc gaacaggctg cgacgcttgc aggaatgccg cagagcccaa cagcgtacaa 2207761 cccggtcaaa aacccggata aagcggaaaa acgacggaac atcgtactca gtctgatgaa 2207821 aaagcaagga tttatttctg attctcaata taacaaagcg aaaaaagtgg cagtgaaaga 2207881 cgaaggcgtc gtgtcacaga aggaatatga aaaagcaagt acaaacaaat acagcgcatt 2207941 tgttgaagag gttatgaagg aaattgatga aaaatctgat gtcgatccat ctgctgacgg 2208001 attaaagatc tatacgacat tagatacaaa agcacaagat aaactagatg aattaatgga 2208061 cggagacacc gtcggattta ctgaaggcat gcagggcggt gtgacgcttc tcgataccaa 2208121 aaacggagaa gtccgagcga ttggtgcggg acgcaatcag cctgtcggag gctttaacta 2208181 tgctactcaa actaaggcac agcctggttc gaccataaaa ccgattttgg actacggacc 2208241 agttattgaa aataagaaat ggtccacata cgaacaaatt gatgactcag cttatacgta 2208301 ttctaacgga aaaccgattc gtgattggga ccgcaaatat ctagggccta tctcaatgcg 2208361 ttacgctctg gcccaatcaa gaaatatacc tgctttaaaa gcattccagg cagtcggtaa 2208421 agatactgct gtagactttg caaatggact cgggcttggt ttaacaaaag ataatgtaac 2208481 agaggcctat tctattggcg gtttcggtgg gaacgatggt gtttctcctc tgacaatggc 2208541 aggtgcatac agcgcgtttg gaaataacgg aacgtataat gaaccgcatt ttgtaaaatc 2208601 tatcgaattt aacgatggca cgaagcttga cttaacacca aaatcaaaat cagccatgag 2208661 tgattatact gcgtttatga ttacagatat gctgaaaaca gctgtgaaga caggtactgg 2208721 acagcttgca caagtacctg gtgtagaagt tgcaggaaaa acaggaacga ctaactttga 2208781 tgataatgaa gtcaaaaggt acaatatcgc tagcggtggc gcccgagatt cttggttcgt 2208841 tggctacaca ccgcaatata cagctgccgt ctggacggga atgggagaaa acgaggctgg 2208901 aaagaaatca ctttcagctg aagagcaaaa agttgcaaag cgcatcttcg cccagctcat 2208961 cgccgatgtc gatgacggaa gcggatcatt tgagaagcct gacagcgtag tggaagccac 2209021 cgtagaaaaa ggttctaatc cggcaaaact ggcagggcca aatacgccaa gcgataagaa 2209081 gctcacagag tactttgtta aaggcacagc tccttctact gtttctaaaa catatgagaa 2209141 agaagaaaaa gaggaaacag ctaaactgtc tggtttaaac gtgaaatacg ataaagacaa 2209201 tcaatcttta acgttaagct ggaattacga cggagatgcg acctttgctg ttaagcaatc 2209261 tgttgacggc ggcagctact cggaaattca aaacagctct gcaaaagagg cagttatttc 2209321 gggtgtgcag ccaggatctg tatacaaatt cgaagtaaca gccgtcagtg atgatggcaa 2209381 aagtacagct tccacatctt atgaggtgcc aaaagctgaa gacgatgaag ataaaaaaga 2209441 ccagcaacaa acggatgatg aaaaacaaga tgatgagaag actcaggatg atacacaaac 2209501 tgatgattct caaaaagatg acggtcagac ggatcaagat cagacagatg attcaacaaa 2209561 cgatcaagac aaaaaacaag acaatacgaa caccaatccg tccgacaaca ataaccaaga 2209621 ccaatcaaac gataatgata acgacaacag taacaaccag gatacgtcgg atggtgattc 2209681 gaactctggt aagaatgatt caacaggttc tgacacgaat aaaaataaaa cagacacatc 2209741 taataaaaca caaacaaact catcatccat tgaaaaaaca aattaaacaa aaaagccgtc 2209801 acctttgggg tgatggcttt tttggtacac aataaaaaac ctcccgtttt aacaggaggt 2209861 tttatcgatt catcgcatga tatttataaa aatgcttttt catttcggta atcagctcat 2209921 caagctgaat aaagcaatgg tattgggtcg gcttaagaag aataaattcc actcgttcag 2209981 cccaattaat cggctttgcg ggatatgatt tctccctcag ttcttgccaa tcgagcgatt 2210041 tcaccggctc acctgctgtc caatgtaacg aagccagcaa acacacaatg ccctttaaca 2210101 tttcgttttg gtcacatctc gattttcgtg tttgaaagac tgggagaagt gatgctttga 2210161 tgtcatccca cacttcaaat aaaagcggaa cgtatttccc gctgtcctcc catggcaaat 2210221 cgccttgtaa ttccgtgcag aaatcaaaat acacgggatt ggtctgcaag gttttcttca 2210281 tatccgagga actcttctgg ccaagactgc gcaagtattg ctcataggaa gccaacactt 2210341 cttttgcttg cgtcatcgtt tcaccagtcc ttttttatcc ctcttctgcc cttctctgca 2210401 caaagaaagc agcggacact ccgcacagcg cggagattgg gctttacagt gatatctgcc 2210461 gaagaaaata agccggtgat gcgtaacgga ccaatcttct ttgggaacct tgcgcatcag 2210521 cgtcttttca acttccagaa ccgagtcctt ccaccggcaa atgcccaatc gtttgctgac 2210581 tctctccaca tgggtatcta cggctatggc cggcacgcca aacgcaacgg ataccactac 2210641 gtttgcggtc tttctcccga cccctggcag tttgacaagc tcatcgcggt ctctcggcac 2210701 ttctccgccg taatcttcaa taatcatttt actcagcttt tgaatatttt tcgctttatt 2210761 acgatataaa ccgattgatt taatatcctg ctgaagctct tccagcggaa cagccaaata 2210821 gtcttccggc cgtttatatt tttggaataa tgttttggtc actctgttta caagtgcatc 2210881 tgtacattgc gcagataaag caacagccac cactaattca aaaggattgg aatgaaccag 2210941 ttcacactcc gcatgaggaa acatgtcacc tatcttgtct aaacagaatt caatttgttt 2211001 tagatttaac acgattgtca ccttttcact ttattgttca agccaattgt aaaaaggaac 2211061 ctgcctttta tactcttttt gcggttcatt ctgctttgct tgtacacgcc ggaatttttg 2211121 gctgtgtatt tttgcctgct ccacagtttt aagcccattt ttcttccatt caaacaaaat 2211181 ccggtcaatg tagcggaaac tgagttttcc tgatagtaca gcctctttta acgcgtgttt 2211241 gatcagttgt gcgtcatgct gatcctggtc ctgccagatc gccagcgttt cacactccaa 2211301 aggcgataac ggtcttgcga actcttcctc aaaaatggta taaaggcttt tttgttcccc 2211361 ttctgctttt ctttcctgtg tttgattctg tgcaagctga atatactcgt acagcttgcc 2211421 ccataaaggc tgaagagaat atttctcaaa tttgatgccg ttttgatcct cgcattcttc 2211481 aataaacaga aagccttttt gaataaacat ccgcaatctg tttgtacatt cttcaacaga 2211541 aattgacata ccttcctgca gctgattcgg tgtaggaaaa tatgatcctt tttctaaatg 2211601 cattttaatt tttaacagca gaataagttc tgtttcatta agcccaagct gtttataatg 2211661 cgtgagcaga agattgggga tggttgatgt tccctgctcc tgcatatcaa taaattgctg 2211721 ttttttcatc gtcacacctc ttactgtaaa ggattgtgat tgccccttta ctgtaaaaag 2211781 tctcccttgc aggagactct tttttgtttc atttgaatgt attacggata cagacggttt 2211841 aacagtcttg ggaacggaat cgtttcacga acgtgaggcg ctccgctgat ccaagctact 2211901 gtccgctcta atccaaggcc gaagccggaa tgaggaactg atccatattt tctaagttca 2211961 gcataccatt tataagcgtc agaatccagt ccatgttctt taagacgcga ttccaaaagt 2212021 tccatatcgt gaatccgttc agacccgccg atgatttctc catagccttc cggcgcaatc 2212081 aagtcagcgc aaagcacaac gtcctcacgg tcagaagccg gctgcatata gaacggtttt 2212141 aaggacgtcg gatagcgagt gatgaatacc ggtttgtcat aatgttcagc aatcgctgtt 2212201 tcatgaggcg ctccgaaatc atctccccac tcgatatcgt caaagccttt ttctttcaga 2212261 aattcaatcg cttcatcata cgtaattctt gggaacgggg ctttgatttg ctcaagtttt 2212321 gacgtgtctc ttcccaatgt gtttagttca attttgcaat ttttaagaac tgattgcacg 2212381 atgaaagaaa cgtaattttc ctgtacttga aggttttctt caaattctac aaacgccatt 2212441 tccggttcga tcatccagaa ttcgattaag tgacgctttg ttttagactt ttccgctctg 2212501 aatgtcggtc cgaaagagaa tacttttcct aaagccattg ccgcagcttc catgtagagc 2212561 tgtccgcttt gagacagata tgcatcttca tcaaagtact ttgtcgcaaa gagttctgtt 2212621 gttccttcag gtgcgcttcc agtcaaaatc ggcggatcca cttttacgaa gccttcgtta 2212681 ttaaagaatt cgtaagtcgc gcgaatgatt tcattacgga ttttcatgat cgcatgctgg 2212741 cgctttgaac gcagccataa atgtctgtga tccatcaaaa attccgttcc gtgttctttt 2212801 ggtgtaattg gataatcggt cgcttcgtga atgacttcaa tatctgtcac agcaagttca 2212861 tatccaagcg gagaacgctc gtcctctttg acaatccctt ttatatagag cgacgtttcc 2212921 tgcgtcactg atttagctgt ttggaaaatg ctttcttcca cttccgcttt tactacgaca 2212981 ccctgaataa aaccggtacc gtcccgaagc tgtaaaaacg caattttccc gcttgaacgc 2213041 ttattagcga cccaagctcc gatcgttact tcctcaccta cgtgcttgta cacttggttg 2213101 attgttgttt tcaacatatt tccctccaaa acaagaaaga cattcggaag ctcattgccc 2213161 cgcgaactct tttatcatca ctttattata cccgctctta actaaccggg tcaatgcaga 2213221 taaaaagcgg cttttctgtc agccgctttt tgatctgtta gctatgtttt tctacaaaac 2213281 gcttgattct ttcaatggct tcttcaagaa gatctaacga tgttgcataa gaaagacgga 2213341 cattctcagg agagccaaat ccggatcctg gaacaatcgc aactttttcc tcctcgagaa 2213401 gcgctttaac aaattcatct acatctttga aaccgcaaga ttgagctgcc tcttttgcat 2213461 ttgggaacaa gtaaaaagca ccttccggct tcacgcagct gaaccctggg atttctatga 2213521 gctttgcata gatcgtattt aatctatgtt caaatgcttc tctcatttct tccaatggct 2213581 cagaaggccc gttataagca gcaatcgctc cgtattgtgc gattgatgtc gggtttgacg 2213641 tgctgtggct tgcaaggttc gtcatcgctt taataatgtc ttcagagcct gccgcataac 2213701 cgattctcca gcctgtcatg ctgtgggact tcgatacgcc gtttataatg accgtttgct 2213761 ctttcagtct gtctgacagc tgtgcaatgg aaacatgttt ctttccgccg tatgtaagtt 2213821 tttcataaat ttcatctgac acaatcaaga tatcatgttc aaggcacact tcaccgagcg 2213881 cagatagttc ttcttccgta tacatgacac cagtcgggtt gcttggagag ttaataacga 2213941 ttgcttttgt tttttccgta attgcatttt tcagctgctc aggcgaaatt ttgaagtgat 2214001 tttcctcaag cccttctaca taaacaggct ttccgccagc gagtttcacc tgctccgggt 2214061 agcttaccca gtaaggcgtt ggaataataa cttcatcttc ttcatccaaa atcacttgga 2214121 aaagggtata cagagcatgt ttggcaccag tgcagacaat aatttgagac ggtttgtatt 2214181 caatattctg gtcgcgttta aatttctctg caatgctgtt tttcagttca gccaaaccac 2214241 cggaaggcgt gtatttcgta tggccctcgt tcatcgaacg cacagcggca tcaataatat 2214301 gctgcggtgt attgaagtca ggctcgcctg ctcctaagcc gatgacatca tggcctgcgg 2214361 ctttcagttc tttcgctttc gctgtgattg ccagtgtggt tgatggtgtt aatgcggata 2214421 ctctttttgc cagtttcaac ttgaactccc cctaattcgt cttaaggcgt gatatttttg 2214481 agaatctttc cagttgtaaa gtccacataa cttaaactgt attgcccttc tttgtctaag 2214541 tacgtcactt cccaaagcag gacgtttcct tctcttgcca gatgaacctc tttttgcttt 2214601 gaaaccagcc cttcatcctt tatgattttc gccgctttgt cttcagagat tccctctttc 2214661 gcttcttttg agagaatttt tgctttttta tcagcaggaa cccagacata taatgcagtg 2214721 ccttttttat ccgttccctt tacaacataa tatttttctt ttccgacaaa tgtttcgact 2214781 tgatcaacat gggcgagatc ggtttctttt ttagcttcag cagctgctgc ttcgtgcccc 2214841 tcttcctttt gtgccatggc tgatttataa atgcttgccg agacaagaag tactgctaaa 2214901 aaaataatac caaaaatgac ggtaaatatt aatgcttttt ttctcatctt ctcacctacg 2214961 tacgataaat ggtaaaaacg gcttggtttt tgttttcttc atccagcgca aggccgaaca 2215021 tcagattgtc tcttttcagt gtacgattca atgtgtccac aattttatac agatcatcag 2215081 aatgctctac attaattgtt gaaagaattt cgattttact ttccattttt tcatcctcca 2215141 gtttgaacaa atattgttag tcatactcca tttcaggaca cgccatacta gtatcacaga 2215201 gcgggaaatc cgcttttaaa taaaacacca tcctactccc acaccgcaaa agccgcttta 2215261 tgcggctttt attctttttc ccctgcaaca taagcttcaa gctcgctgtc agtcatttcg 2215321 gatactgagg ttgtcggcaa ggcatcaaga aacagccggc cgtaaccagc ggttttaatc 2215381 cgtctgtcca atataataat cgttcccttg tctcccgcag aacgcagcaa gcgtccgatt 2215441 ccttgcctga aggtcagcac agcttccggt aatgacactg tttgaaacgg attctttcct 2215501 tttttgcggg caagctcaca ttttgcagca tgaagcgggt gatcagggga ccggaatggg 2215561 agcctcacga tcattactgt cgtcagctca tcaccaggga aatcaacgcc ttcccaaaaa 2215621 tgatttgttc cgagcaggat cgcctgattg gatgttttaa aagtcttcat cagtttgccg 2215681 ggacttccgc ctgtaatccc ttgtgccaag agctgaatgc cggaagcact catgttatgc 2215741 ttaagctcct ggtgaacctt tttcagcata tcatgggatg taaacagcac aaggatttta 2215801 ggctgttttt cctttgccat cagttcgata taacgggctg tatcctgtat aaattcaggt 2215861 tgccctgtat cctgaattga tttcatttct tttggaatca tcacctgcat acgctcatcg 2215921 taagaaaagg gtgactcaat tctcattgtc cgcgggaaaa agtcactcag tcccagtcgt 2215981 tcaatcataa attgaaaaga accttcgact gtaagagttg cagatgtcag caccacacta 2216041 tttttgcgcg cgaaaaactg atcagccaga agttcaccag gttcaagagg ctgtgcgtaa 2216101 atggccactg catttttcgc accctttgca tctatttcaa tccaaaccgc ttcatcgtca 2216161 tcagagccaa agaagagctt ctgcaacgtc tgacagtaat gctgcaagcc tttcatgctt 2216221 ctttggtatt catcggctaa aaagacggtt ttgctcttca tgcccttcaa atgtttttcc 2216281 ataagggatg actgcgcctc aaaaagctgc tgcaaatgtg tcagcatgga acaaagcctc 2216341 tccgcaccat ctgttaagat cgaccagctt ttatcctggc tttctttgtt caccttaaac 2216401 actagacggt ttaagtcttc tttaggtttt cttcgtttga caaaagaatg tacagagcta 2216461 aagaaagcat cactttctgc ttgaacgtgc tgaagccact cttccaattc gaaaaatgaa 2216521 tcaaccggca ggctgtttcg ctggaatagc tgtctcatct tttttagaag tccctgctcc 2216581 ttcagagtgc cgattctgct caatttcgta tgcaattcta tgtacgtggc tcttttccct 2216641 aaatgttcgc ttgccgcacg ttcaaaatgg tgtgcttcat caataataaa tgtgccgctt 2216701 tcgggaagcc tttttttatg gctgccttca tcggtcagca aaagagaatg attggtgatc 2216761 accaaatcgg aacgcatagc aatctgtttg gcccgctcgt aaaaaccgat cacatgctca 2216821 ctgcgacttc ttttatagga gtcatcgtca taagccaatc tgtcccacag caattttccg 2216881 cctgaaggca aattcagttc cgctacatct cctgtatttg tctctgtcag ccaaacaaga 2216941 agctgtgcct ttgtcagtac ggcatcataa ttatcatctt cttcatgaag cacctgctca 2217001 aatttataca ggcataaata atgcgattgc ccttttaaaa tcgccgctgt taccggaaat 2217061 ggaaacagat cttggacaat cggcaaatcc tttgtgagaa tctgctgctg taaaagcgtc 2217121 gaatacgtgc tgattatgac cggctttttt gatttcttgg caaaaagcgc agccggaata 2217181 agatagccaa tcgtttttcc gatgcctgga ggagcttcaa tcagcgcatg ctcacgattg 2217241 gcaaacgcat cagccacctc tctcatcatc atcatttggc cgtctctttt ttcataccca 2217301 ggcattaact ctgacagcgc tttttcattt cccgcttccc agctttcgat ctcaaatgag 2217361 aagttctcgt cctcatttat acgaacatcg atagcttcag gttctctgac agaaaacgaa 2217421 gaaaagcgcg tatagcccgg tatctcggta tgtctgtttt cattaatgaa catatccaac 2217481 aaatgcgtca gatcactgat gaaatgctgc gaaagccttc ttaactgctt taatgtcgga 2217541 taaggaagct gccgcagctt ttcaaggatt tccaaaaaaa taagccctgt cacttcagca 2217601 tcgctgtcag cccggtgcgg ctgatcatgc cgcagctgaa gctcctcgct taattccgtc 2217661 agcttatacc cttcaaatcc cggaaaaaca atgcgtgaga gctcgacagt atcaagcact 2217721 tcacaatctg ggagctgaaa gcccgcctta tgtagctcat acttgacaaa tccaaggtca 2217781 aaatggatat tgtgggcgac aaaataagcg ccgtcaagca attggaatac ttcttcagca 2217841 actgcttcaa atggctgttc attctcgacc atttgattag agattccagt aagctgctca 2217901 ataaaagcag ggattgattt atttggatta atgtattttg aaaaccgctc agtaatttgt 2217961 ccattttcga ttacaaccgc tgcgatttgt atgattttat cgcctttctt cggcgaattc 2218021 cctgttgtct ctacatctat aacaacgaac cgttgcttat tcattaaaat ggacacctca 2218081 attcttgcat acgacaaaag tgtaacacgt tttgtacgga aatggagcgg caaaaccgtt 2218141 ttactctcaa aatcttaaaa gaaaaccccc gataaagggg gcttttcttc tacaaaattg 2218201 tacgggctgg ttcgttcccc agcatttgtt caattttgtt ttgatcattc agaacagcca 2218261 ctttcggctc atggcttgcc gcttcttgat cagacatcat tttgtaggaa ataataatga 2218321 ccttatctcc ttcctgcaca aggcgtgcgg ctgcaccgtt taagcatatg acgccgcttc 2218381 cccgtttacc aggaataata tacgtttcaa gacgtgctcc attattatta ttcacaattt 2218441 gtactttttc attaggaagc attcccacag catcaatgag atcttcatca attgtaatgc 2218501 ttcccacata gttcaggttt gcttccgtaa cagttgccct gtgaagtttg ccgctcatca 2218561 ttgttcgata catattatat tctctccatt tctcgaatat caataatgat attatctatt 2218621 aaacgcgctt ttgaaaaagc aactgcaaca gcgagaatca tctttccagc aatttcattc 2218681 acaggctcga gttccggata ggaataaagc tctacatagt ctatggttcc gctagtcgtt 2218741 tcaatgatat cttttgcagc ttttatcacc gcttcaggat ctctttcacc ggcttggaca 2218801 agttccgcac ttgtttgaag ggcccgatac agcttaggcg cttcttttct ttcctcagct 2218861 gttaagtata cattgcgaga gcttttggct aagccgtctt cctctctgac cgtatcgaca 2218921 ggaaccaatt caatatccat gaagaagtcg ctgattaacc catcaacaac agctacctgc 2218981 tgcgcatctt ttaaaccgaa ataggcacga gtcggcttga ctagattgaa aagcttcgtc 2219041 agtacgatcg cgaccccgtc aaaatgtcct tctcttgagc gcccgcataa cacgtctgtg 2219101 cgtctttcta catgaatcgt gacattcttt tcaccgggat acatatcatg agcatctggc 2219161 gtaaaaagaa tatcgactcc ggcgttttct gcaagagctg catcccgctc aatatcgcgc 2219221 ggatatgctt caaaatcttc attagggccg aattgtgcag gattcacaaa aatactcata 2219281 ataacggcgt cgttttcttg tcttgctttg tctgctaagg ttaaatgccc ctcatgcaga 2219341 aaccccatcg tcggaacaaa tccgattgac ttgccctctg aatggtattg ttttatggct 2219401 tctttcagct gtgaaatatc agtaatctgt ctcatcttat tttcccccgt acaagccgtc 2219461 aagcactgtc tggttcattt gaaaggaatg cttttgttca gggaaagcac gatgtcttac 2219521 atcctgaaca tatccgctga ttgctgtttc gatggtttca tcaatgcgcg tatattgctt 2219581 tacaaattta ggtgttctct caacaccgtg gccgataata tcatgataaa cgagaacttg 2219641 tccgtccgct ttcacaccag ccccgattcc aatgaccggt atgcttagcg tctcggcaat 2219701 tttggctgtg agttctgccg gcacacattc cagcacaagc atcatagctc ctgcttcttc 2219761 gcattttata ctgtcttcta ttaatttttt ggcgctttgt tcgtctttgc cctgtacttt 2219821 atagccgccc agtacgccga ctgactgcgg tgtcaaacct aagtgactga ctactggaat 2219881 gcctccaagc gtcaatgcgc gaatggattc aaacacgcct tctccgccct caagcttcag 2219941 tgcgtcagct ccgctttcct gaacgatagc cgctgcattt ttcagcgtat cttccttaga 2220001 caggtgataa gacataaacg gcatatctgt cacaataaag gtattcggcg cacccctttt 2220061 aacggctttt gtatgatgga tcatgtccgc aactgtcaca ccgacagttg aatcaaggcc 2220121 gaggacgacc attccaagtg aatcaccgac taaaatcatg tcaactcccg cttgttcagc 2220181 aagtttagct gccggataat cataagcggt cagcatgaca atcggttctt cagactcctt 2220241 catttttaga aaatccagtt ttgttttcat gttttctcct cctcatgttt agaggagatg 2220301 atctgccgtt ttcttctgca agccaaaaaa ccttccgtta caacgagaag gattcttcac 2220361 tttctaaagt tcggcgagtt tcatccctct gtcccagtcc ttttttggat caaggcagac 2220421 tgctgcaatg tctatctatt ttaataatag gtgcagttcg caggcgatac tgcccaatgg 2220481 aagtatacca aaatcaacgg gcttgtacca acacattagc ccaattcgat atcggcagaa 2220541 tagatttttt taatgccttc gttcgtttct aaaagcagaa cgccttcatc atctatacct 2220601 aacgccttac cgtaaaaggt tccgtttaac gttctggctc tcatattagt gccaataccg 2220661 agcgcatagc tttcccataa aagcttaatc ggcgtaaatc cgtgcgtcat ataatcccgg 2220721 taccgtttct caaagcatag taaaatatgc tggatgacgc cggcccgatc aattttttcc 2220781 ccagcagctt ggctgaggct tgtcgcgatg tccttcaatt catctggaaa atcattaggc 2220841 tgctggttaa cgttaatgcc gatcccaatg atcactgaac gtacgcggtc ttcttcagcc 2220901 tgcatttccg ttaggatacc gactgttttt tttccgttaa tcaaaatatc atttggccat 2220961 ttaatatccg tttggatgcc tgctgcctct tctattccct gcacaacagc tactgcagca 2221021 agcagagtca gctgcggtgt tttttggagc ggaatgtcag gccgcaaaat caggctcatc 2221081 caaacaccgt ttccttcttg agaatgccat accctagaca ttcggcccct tccggctgtt 2221141 tgtttgtcag ccaccacaag ggtgccttcc ggtgcgttat tattcgcgag ctcatgagcc 2221201 gttttttgcg tgcttgaaag aacgtcatgg taaataagat gctggcccat cacttccgtt 2221261 tttaatccaa aacgaatttc gctttcactg agttttccgg gttttttgat gagccgatat 2221321 ccttttcttc taacggcttc tacttcataa ccctctttcc gaagctcttc aatatgcttc 2221381 cacacagcag ttcttgaaca gccgagagca tcactgattt tttggccgga aataaattca 2221441 ttgccggcct gagaaaataa ttcaataagg tcttttctta atgttgaccg catgtcttca 2221501 gccactcctc tatgtgtttc ttttgattgg agagcttccc tgtcacaaca gcctgctcga 2221561 tccactgtaa ttcttctgac acccattttc cggccggccg gtttcgaagc gcaagcaagt 2221621 ccttacccgt gatatcaaga tccttaaggc ttttgatcgg caggttttga taagcgtact 2221681 gaatgtcctt cagtttcttt tcatccagtt tttcgttttg ccgaagctgc gatattttgg 2221741 ccgctgagag cagtgctttt ttcccagctc tgtacattgt cattgcgtca aggctctggc 2221801 caaacgtatc ggcaatgtga atggcttcct tgatcacttt tcccgggagc ttccaggctt 2221861 tcaggaaaag gggcgcgtct ttcaaaacta tgccaaggtt aattaaaaga gcagcccaaa 2221921 gctcctcacg ggatgttaaa gagaagaatg gaaactcact cgttgaaatc aggttttctc 2221981 gtttatgata aaaaccagga agctcttcat acaatctcgt ttgaatgagt gtttgaagcg 2222041 cctggcgaga agctcttccc tgcagcaatt tctcaaactc tatagttttt cgttcgactg 2222101 aaacatggga gaggagtgat ttttctttcg caatggcttc ttctgtttcc ggtgaaagcg 2222161 taaagccaag ctggctcata aagcgtacgg ctctcagcat acgaagcgca tcctcttgaa 2222221 atctatcctc aggctttcca acggttcgaa tcactttctg atcaatatct ttcttgccgc 2222281 caaaataatc aagcaccttc ccgtccgctg tcatggccat cgcattgatc gttaaatctc 2222341 tgcgttttag atcctcttct aatgatgaga taaattgcac ttctgacggt cttctgaaat 2222401 caacataatc agattcagtc cggaatgtcg tgacttcata ggtttcatcc tcccagagca 2222461 caataatggt cccgtgctct ttgcctacat caacagtccg ctgaaacagc cgttctactt 2222521 gatcaggtgc cgcatctgtc gcgatatcga catctccgat cgttcgtttc atatagctgt 2222581 cacgaactgc gcccccgaca aaataagcct gatggcccgc ttcgattaag atgcggagca 2222641 cgggaagtgc tttgataaaa actttttcca tgtgatcact ccggttctgc taaatcggca 2222701 taaatctgtt catactggct gacaattttt ttagaagaaa attcattttc aagcatctct 2222761 attgccgcct ttgtaaaacg attgcttagc tgttcatctt ctaaaatgct catcgcgcgg 2222821 gctgttgcgg ccgtaacatc accgacatcc accaaaaatc cgctcacatt gttttttata 2222881 acctcaggga taccgccaat gtttgttcca atacaaggca ctccgcaagc catcgcttca 2222941 agcaggacaa ggccaaagct ttctttttca gatagcagca gcttcaaatc gctaatagaa 2223001 taaagatctt caacacggtc ttgatttcca agcattaaga cttggtcttc caagccatat 2223061 tttctgataa gctcgcaggc tgtcgatttc tccggaccgt ctccgactaa aagcagcttc 2223121 gctttcgttt tgccagcgat attgcggaac acacggatga catcctgcac gcgtttaact 2223181 tttctgaagt tggacacatg gatgacgact ttttcatctg gtaaaattcc atgtttctct 2223241 ttaattgccg ctgtgttttt cttcagatac acgcgctcgt ctataaagtt ataaatcgtt 2223301 tcaatttttt tctccggttt aattaaatcg tatgtttcag ccgcaagcgc tgaggagacg 2223361 gccgtcaccc tgtctgatga ctcaatagca aaacggatca gatcttttag agacggatca 2223421 taacctaaca ccgtgatatc cgtgccatgc aaagtggtaa caatgccgat attgcgtttc 2223481 agcatttgtt ttgcaagata ggcgcaaacg gcatgcggga gagcatagtg agcatggata 2223541 atgtctaaat tctcccgttc cgccacctca gcgattttgc ttgccaatgt caaatcatac 2223601 ggaggatact taaaaacagc atattgatta acctcaactt catgaaaatg aatattggga 2223661 tgatatgtat tcagtctaaa cggaatgctt gatgtgatga aatggatttc atgtcccttt 2223721 tcagcaagct gcttccccag ttctgtcgca atgatacctg agcctccaac gctcggatag 2223781 catgtgattc ctatttttag ttttctcatt gttcgccccc aagcacatca tgatcaagca 2223841 tcagcatccg tttggaaaag aaaccttcgg catactccac gcccgcttct ttaccgtaaa 2223901 gcttttctct cgcttcaacg atttcaatat acccattcgt cagaggagta gaaacggaat 2223961 cctttgacgg gataaactgg cttttgtagg cgttgaggct ttgtttcttt gcctctattg 2224021 tatccgagat atcaataaca aaatccggct gatgaaaacc atttatcata taatagtaaa 2224081 ccttgctgac tttatgcgcc ggaaggcttt tttcgtcttt atatttatgg attccggcgg 2224141 aaaagatcgc ttcttccacc agtgcagccg cattgccgtg atccggatgg cgatcctttt 2224201 tatacggcat aaaaaccgct tttggccgac agattctgat gacagtgaca attgaccgaa 2224261 ttgcctgatc actcattatt aggccgcggt ctggaagcgt tagctgaatt cttttatctg 2224321 cgcctaatat gcgggctgct tcagctgctt cttctttacg caaactgacc gtaccgttag 2224381 aagagagttc cgcttctgtc aaatcgcata tcattacttt tttttcctgt ttgacaaact 2224441 tcgctattgt gccgcccatt ccgatctcga catcatcact gtgggcgcca aaagcaagaa 2224501 cgtcagcatt atacattcgg ctcttctccc cgaagaaggt cacggaattc gaaaacacct 2224561 tcatcaagtg tgcgcacaag aatttccgca gtacccatat ttgtggcgag cggaatggaa 2224621 tacacatcac ataaacggat taatgccgag acatccggtt catgcggctg cgcggtcagc 2224681 gggtcgcgca aaaaaatgac aagatcgagt gcattggcag cgatcagtgc accgatttgc 2224741 tggtctcccc ctaaagggcc ggattgaaaa cgttcaattt gaagacctgt cgcctcatga 2224801 attttcaacc ctgtggttcc ggttgcgtat agatcatgat tctttaaaat atcccgatag 2224861 gcagtcgtaa attgaaccat atcctgtttt ttcttgtcat gcgcgatcaa agcaattttc 2224921 attgtttatc cccccgtcta atcaatgata ttttctaaac catacacaag ctgatcaatc 2224981 ttcatgactt gttcgactga cagtttaacg cctgacatga aagaagcacg gttataagaa 2225041 tcatggcgta tctgaagcgt ttggccatcc atgccgaaca tgacctcctg atgcgcgatc 2225101 agtcccggaa gacggacgct gtgcaagcga ataccgtttt gctccgctcc tcttgctcct 2225161 gggagaattt ctttttcatc cggatgtcct tgctgctttt ctttacggac ttctgaaatc 2225221 atttccgctg ttttaagcgc agttccgctt ggtgcgtcaa gcttctggtc atgatgaagc 2225281 tcaataatct caacatcctc aaaatagttg gcagccattt ttgaaaattt catcatcagt 2225341 atcgcaccga gcgcaaaatt tggcgcgatg atggctccga tccctttttc ttctgttaaa 2225401 gatgtgagct cttttaaatc agcttctgag aaaccggttg ttccgacaac tggacggact 2225461 ccgtgctcta atgcaatttt tgtatgtact tttccgattt cgggcgttgt taaatcaatc 2225521 aagacatccg gttgtgtttc tgtaaaacag gcatggatat ctgtgtaaat gaaagcatct 2225581 gactcaacag gcatcacatc agataatttt tgctgatcgt atgtatggtc tatggcccct 2225641 acaaggtcaa aatgtggtgt tcgttctgcc aatttaacag cttcctgccc cattcttcca 2225701 cgcggtcccg caatgactaa tttaattgtt tcgtttgaca tcttgatctc ctctactttc 2225761 cttcttcttt tctggtccag cgatctttat ctcttgtatt aaatttatgc atgactcggt 2225821 cgtgagcttc ctctaaagag atatcaagag agttggctaa acaaaccaat acaaatagca 2225881 catcgcctat ttcctcttcc atgcttttat catcttcagt cgcttttttt ggtttttctc 2225941 cataacggtg attcacttct ctggcaagct cgcccagttc ttcagtcagc ctcgccatca 2226001 tggccagcgg gctaaaatat ccttctttaa attggcctat gtaacggtct acttcagcct 2226061 gtatgtcttt cattgtttta tcactcactg aacgaaacct cctatcatcc tcttacatgt 2226121 tagctaattc agatacgttt gacaaatgtt taagcacgtt tgctgttttc tttttcatcc 2226181 actataatat aaacgctatc taatggaagg aaaaggggtt ttgtgtgatg cttggagaaa 2226241 ttagattaaa aaacatattt tttattttaa tcggagcggc aattttttca tttggcttgg 2226301 ttcatttcaa tatgcagaac aatctggctg agggcggttt tacaggtatt acacttttgc 2226361 tttatgccct tttccacatc agcccctcta tatcgaacct ggtgttgaac attccgattt 2226421 tttttattgg ctggcgtttg ctcggcagga caatgtttgt ttataccctt gtcggcactg 2226481 tagccttgtc tttgttcctc agcatctttc agcgatatga aatccatatg ccccttcagc 2226541 acgacttagc gctcgccgct ttatttgccg gcgtattcat cggagccgga ctgggtatta 2226601 tttttaagtt cggcggtacg acaggcggtg ttgatatcat cgcacgttta gtgaataagt 2226661 attttgggat tccgatgggc agaacgatgt ttgctttcga tgcctgcgtc atcattttgt 2226721 ctttgcttac ttatctctcc tataaagaag cgatgtatac gctggtagct gtatttgtag 2226781 cggcaagatt aatcgatttt attcaggaag gcggatacgc tgctaaaggc gctacgatca 2226841 tctcttcgaa aaacgacctg attcagaaaa agattcttga agaaatggaa cggggcgtca 2226901 ccattttgaa aggacaaggt tcctacacaa aagaggatat agatgtactt tattgtgtgg 2226961 tgccgaaaaa tgaattggtg atgctgaaaa gcgtgattaa ctccattgat ccccatgcct 2227021 ttgtagcggt aagcgatgtt cacgatgtgc tcggagaagg atttacgctt gatgaaaata 2227081 aaaatccgct tccgcgctga catgtaatag aaaaaaggcg gctgaccgcc gcccctcatc 2227141 cttatttagg gtagtccctt tttttcagct tgtttttttc cgccttgtac tttctgtaac 2227201 cgacataggt aagagcagta atgatgatac tgccggttgt aatgatcacc cagagtaaag 2227261 acggatcggc atcatcctcc tccaccctgt caaacacatt tttcaggtca tgctgaagaa 2227321 gggaaagccg ttcaagcttc gtgctctctg tcatttgctg aaattcctct tgctcaataa 2227381 catctatatg ttttccgact gtttcaagct gatcctctga tacatcgatt gtaagactgg 2227441 ggtaaatcaa gtcatataaa ctgataaatt cattccattt ttcatgaaag cttgtgcttc 2227501 cattcttttg gacatctcgc ttcagttcag taaaagcttc cataatcggt ttttccagtg 2227561 agccccaaag cgggtcagac cgattgtcaa ccgcatccat cagcattctg aactgcgcgg 2227621 ctgctctgag tttttgtgtg tctgatgtat cagcttgctt taaactccga accatatcat 2227681 tatagcccaa tgtgatttga cgaatttggg ctcccgttag catggggtct tgctgttttt 2227741 tctcagcgga ttttaatgtt ttttcaaaat actccaagac ttgaagcgcc tcttcatatt 2227801 tcgcctgtcg ggtcatttga aagactgtat cggataaatc attcaattcc tcgaggcttc 2227861 cccgctctgc agccttggca tttccattat aaaaaataag tgcaatcaac aaacagatcg 2227921 tcagctttcg tttcatgcag gtccctccca ctctctctcc ttacagaata tgaagaaagg 2227981 gacaaggata gaccaacatt gtctttacat cagctcaagc ttcgtttgct tttttgagac 2228041 cacaagaaag taagcaagcg cgattgaaaa gatacttagc caaaatgttc cgtatcctat 2228101 ttcagtcata taatcagaaa gcatagagta ttgcggcatc atatcaaaca agtagtcaat 2228161 gacatcgtta tgcagtgtcc agactgcagc aattgcaaga tgccaaaatg aaaaacgaaa 2228221 atacggactg tataatacgc cttgaactgc cattgcaaaa tgcgaagcaa ttagcatgta 2228281 gccctcccac ggcaagtcac cagttactgc aagcacaaga aaattcatag ccaccgccca 2228341 taggccatac tttacgaggg taactagcgc aagcgcctct aaaagcggag cattccgttt 2228401 catgagaaag gcaagcagca caaacagaaa gaaaaacgtt gctgtcggac tgtccggaac 2228461 aaaaatcagg aaacgggccg gtgtctccaa aagctgcggc aagtaccaat agtagccgta 2228521 aaccgttccc agaaaattaa tggctaagac aagaataagc atcggccgct gccctaatac 2228581 atattgaaac catttcacat cgaatcaact ctcagtctgt aaaaataata tgtccatata 2228641 aaaaagctga cgccgggtca gcttttgata ataaaagtat atccttccat ttgacaattc 2228701 acaatacgtt attttgcggt tgtttcagaa ataaattttg caagttcttc gagctgctta 2228761 tcatttcctt tgaacacacc cgccggcatt ttgcctttcc cttctacagc gatttttttg 2228821 atttcatccg gtttcagccc gctgtcaacc aatgaaggcc cggccgctcc tccctgaagg 2228881 ttatccccat ggcaagaaat acagccctgt tccttaaaaa ccttatatcc ttctgcattg 2228941 gtgtcaatgt cggcttcttt tgtaattttc ccctgttctt ctgccttggc ccagtcatga 2229001 gtagcaactg actgccacgt caaaaataca gcagcggaaa tggccagaag catcataccg 2229061 acagcgaccg gacgcttcca cggccttctt tctgtccctc tgtctaggaa tggagccaaa 2229121 agcagggccc caaaagcgag acctggcata atcatggcgc cgaccactgt aaagcttccg 2229181 gcggcgtatt catacttcaa cagctggtat aagaaaagaa aataccaatc cggcagcgga 2229241 atataaccag tatcagtcgg gtccgccatc cgctctaaag gcggctgatg cacaatcgtc 2229301 aaaacgagaa aaccgatgag aaagacagct ccaaccatcc attcctttaa caagaaattt 2229361 ggccagaaag cctctgtttt acccggatac tccgaataat ccttcggtat attcggcttt 2229421 ttttcagccg gtatccttga gtcgcctaca aatttcatcc ctttgccccg gtgcatgtca 2229481 tcccctccct tttattcgca gatcaagagt ttaaagcggt cctgaaatcc cctgcttccg 2229541 gatcataata aaatgtgcag ccatcagccc gaacaatgcg gcaggaagaa aaaatacatg 2229601 gatcgcaaaa aacctagtca gcgtttgggc gcctacaata tccggatgcc ctgcaaggag 2229661 cgttttaact tgcgttccga tcaaaggcgt ggcttcggcg atctgcagtc cgacttttgt 2229721 tgcaaacaga gccttcatat cccaaggaag caagtagcct gtaaagccaa gaccgagcat 2229781 aacaaaaaag atcagcacac cgacaatcca gttcagctcg cgcggttttt tatacgcgcc 2229841 ttggaaaaag accctcagcg tatgtaaaaa catcatcaca atgaccaggc tcgcacccca 2229901 gtggtgcatc cccctgacaa tctggccgaa tgccacttca ttttgcaaat aatataccga 2229961 ttcccaggca tttttgatat caggcacata atacatcgtt aaaaacattc cagataatac 2230021 ttggataacg gttacaaaaa acgtcagtcc cccaaagcaa tacacaaacg cagagaaatg 2230081 atgggcggga ttcacatgtt ccggtacttc gtgatcggca atatccctcc acatcggtgt 2230141 aatatcaagc cgctcgtcta cccagtcata aattttgttc agcatgtcac ccttccccct 2230201 taggctttgc ttttccaaga tacaggaagc cgtcttttac ttcttgctca taatgatcaa 2230261 gaggcgcaag cggcggcgtg ccagggacat tggtgccgtc cttttcatag agtccgtaat 2230321 ggcatggaca aaagaattta ttcgggtttt taggatcact attccagttc accgtacacc 2230381 ctaaatgctt acaaattggc gaaagtgcta caatttcatc cccgtttttg aagacccagg 2230441 ctgatcttga ctcttctgac tcataccagg catcgacttg attaatttta aaatcaaagc 2230501 gctgcggctc ttttgtcaac tcatcaacgc tgacaacctg aaccatatcc tgcttccctg 2230561 tcgattttaa taccgggtcg agtgcgaagc gaaccatagg catgagcata ctagccgcca 2230621 taaaacctcc tacgcctgtg agcgtataat tcaaaaattg acgtctggat atatcatgtt 2230681 ttccgcccat ctcttctccc ccctctaagt cacccctgca aactgactaa aatagaaaat 2230741 attgcaataa ctctagacac cctcataata tatgaatctc tcagcaaggt caatatagcc 2230801 aaaatattgt ttataaggaa atgtaagtgt ttttataaag tgctccataa ctgtaacaaa 2230861 acgttcaaaa tttcagcagt gcgttcatcc aatatttttc tttttaaaga gtcatttaaa 2230921 tgctctaatg gaacagacga tgtaacaatc attttgccta acgcatcctc agctctccaa 2230981 ctttcgtcag atgtgagcag gacaacatgc ggaaattccg ttatcagctc ttcccgcaaa 2231041 tccttaagcc cttgaacggt tatttcattt ctatcaacat atgtataagg cggaagtaaa 2231101 tatacccgtc cctttaactg cctttcaagt tcttctgaga gaagctgcgt aaactcgcct 2231161 ttctccgccg ccattttaaa atggttatta acccttatgt taattaatgg tatgacagcg 2231221 gtatcaatgt aatccttagc ttgtaaatag tccttggcat cagtgattct ccacctcatc 2231281 gttctccccc tttacggcaa caagccttgc aattcactgc aaggctggtc atattatgtg 2231341 agctgattta attggcgcga taattgttca aatgcctctt tatcatgacg atctaacgcg 2231401 tcgtcaatgt cttttaataa tttttctctt tggaatgtgg aaatagcgtg ctctaaaatc 2231461 tgttccgcca atccctgatc ttttttattc tcaaaaaggt ttttcggaat atgcgggttg 2231521 gactccagca ccgccgcata ttcaggtgag ctgtaagccg aacggaaatt aagctggata 2231581 aacaaatcct gctgtttatt taatctaata tcatgaaaag atttttccgc gtcggtagtc 2231641 atgacattct ctttatagaa ccggaacgga acttcttcaa cacaatgtgt tgacattata 2231701 atgcctctcg ggcaaaattc agcctgctcc acaaaatgaa ccttctccat gagagaatca 2231761 tggctcatta agtagttcaa gatccaaacg cactctcggc gctttaactg ataatggttt 2231821 aaaaaccaac ggataaaatc ttttttctca ttgacagaaa caggggtctg catgtaattc 2231881 cctcctctat cgttcgtata atctatatac ttatatgttc cacatgaatg gttaatattc 2231941 ctgcttatct agaaaattca tcctcgattc gcaaaatcgt ttcttcaagc tcttcattgg 2232001 ctccgtccat ttcaagaacc tttttcaaaa gcggcagcgc ttctttttga agaccttctt 2232061 ctaataggaa gcttgcgtat tcatataaga aatctctatc ctcccggtaa tgaagatagg 2232121 cagcctcaaa ggattgtttt gcttcctcgt attgctctaa ttcagtatat gcgcttgcaa 2232181 gataccaatt gtatttagga tcttcttcac cgtagcttcg aacctcttga ataagatcaa 2232241 tgatctgatc ataatcctct tctttgtgat acacggcaag aagtgtatga agcgcctcga 2232301 caaagcccgg atcaagcgca agcgcctcct gaagcagctt cttcccctct tctgacttcc 2232361 cgattttcaa ggccattttg gcggcataaa ggaaaagttc tttgttatat tcatcatatc 2232421 tgatcccctc ttttgccgtt tttaatgcct cttcatacat tccttcagct tcatagcttt 2232481 tcgagagcgg catataaagt gaagtataag atggatcaag ctcctttaaa tcagacagct 2232541 gcttaatagc tgttttcaca agccccgcct gtaaggctgt aaaaccatag ccgaaaatcg 2232601 tattaggatc aggattctca tcgacagctt tctcatacca tggaatggca tcctcaaatt 2232661 cacctgaggc acttaacgat tctgccagtc tttgatggac attaacgccc ccgatctcac 2232721 tctgctcctc agccgttgtt ttaaaatatt gaaccgcttt tgcataggct ccctgagcaa 2232781 agtaaagttc tcccagtgca aaatcaataa caggttcatt gtccagaatg gactttgcct 2232841 ggaaaagctt ttgttcactg acttcgaata acccctgcat ctgataaaga tccgccataa 2232901 gcagcaaact ttccggatat gatggatctg tttccggaat agtctccagc acagcgaggg 2232961 ctttttcttc ttcgtcaata tctattaaaa gttcagcgta gaaattcgtc agttctgttt 2233021 catttggata taaatcatgt agatcactaa tcagtgaaat ggctttttct acatcgcccc 2233081 actcgtaata aagctgggct gcaatggctt tatcttcatc atgcagctgt ttttcagcct 2233141 tcgagagcgt gttgaggcct ttttctgttt cacctgcttc aactaatttt atggcttctt 2233201 gaatcaatgt attcaaatcg gaccggtcct ttcttttcct atacaacatc aaccatacaa 2233261 aaaaagcttt atttgttcgg gttaatctta tcataattca gacgaatgcc cccggcaaat 2233321 aagatgcttc tgtacggaag ggaattattg agtcttatta gtttaccaaa agatcttgag 2233381 atagaaaatg aaaaaaggaa gatcgccctc tgtacagtaa agcagctctt tgacctgccg 2233441 gcttgtaagt aaagcacatc cccccttttc gtttttctat ccgttctata agacaagcta 2233501 tgttttttcg cctcgaatta tgatctgcat aaaaaatcct gaagtaaaac ttcaggattt 2233561 tttcgaaagc ttatttaaat gctcgaagaa ggttggataa gaaacgtgaa tggcatccgt 2233621 gtgctcgatt tcaatcggct cctccgttat acaggaagca ataccaagca tcattccgat 2233681 tcgatgatct ccgtggctgg acactgcagc gccgcctttc aacgtttgtt tgccataaac 2233741 cttcattcca tctgctgtcg gttcaatttc agcacccagc ttgcgaagct cagaaacaac 2233801 agtatcaata cggtttgttt ctttcacttt tagctctgcc gcgtccttaa taacggtggt 2233861 tccttccgcc tgagtcgcaa gaagcgcgat gatagggatc tcatcaatta aacgcggaat 2233921 gatatctcct ccgatttcaa ctgcctttag agatgacgtt tctataatca aatctccata 2233981 aggctctgca ccgctatcag cagatggttt gatttcaagt tttgccccca tgttttgaag 2234041 gacatcaata atacctgtcc gagtcggatt taaacctacg tttttcaata caattctgct 2234101 gtttggaacc atcgcgccag cagcaaggaa aaacgcggct gaagaaatgt ctccaggaac 2234161 aaaaatatca gcagctgtca gtttctggcc accagcaatg gaaacactcg tttgatcttc 2234221 agaaagctta acgccaaaag cagaaagcat ccgctcagtg tggtcccgag atttatgggg 2234281 ctctgttaca gttgttgtgc cctcagcctg taatccggcc agcaaaacag cagatttaat 2234341 ttgcgcgctt gcaacaggtg atacataatc aattcctttt aatgaagcgc cgctcactga 2234401 cagcggtgta aactctccgc cggctctgcc gtcgatttta gcccccattt ttttcaaagg 2234461 ctcagtcaca cgcttcattg ggcgtttcgc aatgctctca tctccggcta ccgcgctgta 2234521 aaaaggacgg cccgccaata ttccgagcat caggcgaatc gttgtacctg aatttccgac 2234581 atctaaaagg ctttctggct ctttcagggc atcgattcct tttccgtgaa tcacgacatc 2234641 gctgctgctt tgctcaatgt gaacacccat ttttctaaag caatcgatcg tgctcagaca 2234701 atctgctccc ggcagaaagt ttttaactgt tgttgtgcct gccgctagcg cgccaaacat 2234761 aacagagcgg tgagaaatgg atttatcacc gggaatatgt atttctccat gtaaggtctg 2234821 caccttatct cgtttcattt tttccacctc aatcagcata aaaagtttca tattccgccc 2234881 gggcttcaat gcattgttct gcccttttgc ggtcgtcatc agactgaaaa ctgatcctta 2234941 aaatcccgtt aatatcctct cgtgtttcga taatgcggat attcgtgata ctgatgcgct 2235001 ccgcagctaa gatcgctgtt atctcggata ttacacccgg atgatcgggt acatccacat 2235061 ataaatcata aaatgcaggt atcgctccct tctgccgaag cggcagcccg tcgcgataat 2235121 ccttggctgt tttaaaataa cgaaatagat tttccgcatc ttcttgttct acatatgtac 2235181 ggatcttgtc aatttcacga atccactcat caaaacggtc taagatttta tctttattat 2235241 gtaataaaat atcccgccac attgccgggc tgcttgatgc aatccttgta atatctctga 2235301 acccgccggc agcaaaacgc ttaacaagcg gatacaggtt ttccgaatga tgggtttggt 2235361 gaacaaggct agctgctaca atatgcggaa aatgactgat tacgcttgta acgccatcat 2235421 gctcctctgg cgacatttcc acaaaatggg cattcgtccc cttcagcagg ttttttaact 2235481 gttccacagc ttgtttgtcc gttttctggc ctggcgttaa aatataaaat gcattttcaa 2235541 acaggaactc cttcgcagcg gccactcctg atttatgtga acccgccatc ggatgccctc 2235601 cgacaaattg atagcggcta ggcagcactt gatcagcgta atcaaccact ttttgctttg 2235661 tgcttcctac atccgtaatc aaaagctcat gttcaattcc tgaatgagcc agctcttcaa 2235721 gcataaccag tgtttgttca acaggtgtcg caatgattac tgtagctgcc tctttcacac 2235781 cgctaataaa cgaatcagca cgatcgtcta tcacgcctaa ttttaatgcc gctaccgcct 2235841 gttcatcaga gatgtcgatt ccgataatcc gtttgccggg atgatttttt ttgatggcta 2235901 gggcaatcga accgcctatc aatccgagac cggcgagcaa tattgtatct ttcatttgat 2235961 tcatacgtca tcacctggtt tatagactaa agaggtgata tttgatcacc tcttataaaa 2236021 tttcagctaa aatggcaagt atttcttcat tttgctcttt tgttccgatc gtaatccgga 2236081 gtgatgtcgg gaaacctaat gcgtttcctg accggacgat atagcctttt tccagcagag 2236141 cctgaaacag ttcatcagca ggacgtttaa agtcaattaa cacaaaattt gtctgtgaag 2236201 ggtagcactt taaaccatga gttttcgcaa aatcataata ctgctgaagg cctgcattat 2236261 tttgctcgac acaggaagca ataaacgctt gatcatcaag tgctgcaatc gccgcagcct 2236321 ggcccagacg gctggtatta aacggctctc tcgccggctc aatctggcga atcaggttct 2236381 cgtcagcaat tccgtatccg actctgagcg ctgccagacc gtatgccttt gaaaatgtgc 2236441 gcaaaatcat caaattggaa tacttgctta agagcggcac ggtttccggg taatcctctg 2236501 ctgttacata ttcataatat gcttcgtcaa gaacgacaag gacacgagaa ggaacgcgct 2236561 ccagaaatgc gagtaattct ccttcagatg tataagtgcc agtcggatta ttcgggctgc 2236621 atatccaaac gacttgtgtc tgttcgtcga tggcttctaa catggcgtct aaatcatgtg 2236681 agccgtcggg acgaagtgca atttcacgta cttcagcacc ttcaataacc gcattatgtt 2236741 tatattgcgg aaaagtgggg gcagcagtaa ccgtgtttgt tttatcgttt aaaaatgccc 2236801 ggcagatgat ctgtatgatt tcatcagaac cgttgccgaa aataagtgat gtttcgctga 2236861 cattgaggtg cttactgagc cttgtccgca aagcggcgct atacccgtcc gggtaaaggg 2236921 ctagctgttg aatctcatga tgaagcgcct cttttgcagc ctctgaacag ccgtaaggat 2236981 tctcgtttga agcaagcttc acaactttat ccaagccata ttctgatttc actgcttcaa 2237041 tcggctttcc aggctgataa ggcttcagct gttttaaatg ttctttgata cgcaaatcag 2237101 tcacctcatt ttaaactgta caagccgcta aacgccattg cataatcctc aaactcctgc 2237161 agcgcctgat ttctcgtttc agcgctgatg agccggtcct ttaattcttc tatttttctg 2237221 acgagcgcac ttcccactac gacaccgtca ctaatttcat tcatctttat gacctgttca 2237281 cggtttgata taccgaaccc tacagcaacc ggaacagtgc tgagattctt cacagtacga 2237341 atgaacgggt acacggatga attgaactca ttgcggacac cggtcacacc cagagaagat 2237401 acacagtaga cgaacccctc ggcttgttca ataatggttt tcaaacggct ttcgcttgtc 2237461 ggcgcaacta aagaaatata cgtcacctca tggcttttac attcctcttg aaggctgttg 2237521 ctttcttcta atggcagatc cggaacaagc agaccgtcaa tatgattttc ccgcagtaaa 2237581 gcgaaaaagt attctttgtt caattgtaac acaggattat aatacgtaaa gaggataatc 2237641 ggaatattca ctccgttttt tttcatttct ccgcctaatt cgattgcctt tacgatattc 2237701 attccttgat caagcgcccg ctttgaagcc cgctggatca ccggaccgtc tgcaagcggg 2237761 tcagagtatg caacaccaag ctccaatgct gtggcgcctg ctttttggag tgacttcgcc 2237821 agttcaatcg aaacctcagg aactggatcg cccgccgtaa taaacgggat aaacaatttt 2237881 tctgatggtt gaagatccaa tttaaacatg ggctttcacc tcttcttcca atacattcat 2237941 taatgtgttg acatccttgt ctccccggcc tgataaacag acgagaatga gttgaccgcg 2238001 atccattcct ttggcgagtt tgaatgcttt cgctaacgca tgggcagatt cgattgccgg 2238061 caaaatcccc tctttttctg acaaaagctt taatgcatcc accgcttctt catcggttat 2238121 actgtcataa gtgacacggc cgcttttatg caaatatgca tgctccggac cgattccagg 2238181 atagtcgaga ccggctgaaa tagagtaggg ctcaataatt tgcccgaact catcctgaat 2238241 gagataagtc aatgaaccgt gaataacccc tacggttcct ttcgaaatag tggcggcatg 2238301 aagaggtgta tcaattcctt ttcctgctgc ttcagcgccg atcagttcaa catcttcatt 2238361 taaaaatgcc tgaaacatac ccatcgcatt gcttcctccg cctacacatg ccactacttt 2238421 atcaggcata gtgccttcaa tacgtttcaa ctgatccttc gcttcctctc cgatcatttt 2238481 ttgaaattca cggaccactt gcggataagg atgcgggccg acaactgatc caatcatata 2238541 aaagtgatcc tcacaatgct gaacccagta ccggatcgcc tcatttgtgg catccttcaa 2238601 tgttccgttt ccgcttgtta caggcactac ctccgctcca agaagcttca tgcggaaaac 2238661 gttcagagac tggcgggcaa catcctcttc acccataaac acagtacagg aaaagccgaa 2238721 tttggctgca actgttgcag cggcaacacc atgctggccg gcaccggttt cagcaatgat 2238781 tttcgttttg cccatttttt tagcaagcag cgcttgacct agcgcattat tgattttatg 2238841 agaacctgta tggtttaaat cttctcgttt caaatagatt ttcgcgccgc ctaagtattc 2238901 agtgactcga tcagcgtatg ttaatgcagt cgggcgtccg gaatagtcct ttaacagctt 2238961 ataatactct tcacgaaaag cgggatcatc cttgatttgt ttaaatgctg tttgtatttc 2239021 atctaacggc tgcatgagtg tttccggaac aaactttccg ccaaaatcac cgtatctgcc 2239081 tatttcattc ggatatggat acatatcggt tcatcctttc ttctaaaagc ctcatcagat 2239141 tctgatcttt ttgtccgttt ttttcaattc cgctggcaag gtcaattcct tctggctgcc 2239201 atttcaatag gcgtgtgatg ctatccggat tcacgccgcc agcgataaag cagcgtttac 2239261 caatagccgc ctgctgatat tccggcacac attcccaaga aaatgcaaca ccagttccgc 2239321 ctctagaccc ttttacagat gaatcaatca caaagccgtc aacattatct ttaaagcggg 2239381 ctatttcttg agttgtgtta tcttgatggt gaagcgcctt ccatatttca cagcctgtca 2239441 gcttgcgaag agcagcagca tccgccggtt tttcatcacc gtgaagctga atgacgtcga 2239501 gcttcaagct cttggcaata cgtgacatcg tctctattga ttcattaaca aaaacacctg 2239561 caacctgttt ttcgacacga acttggttca gccatttttt cacatcttcc ggagatactt 2239621 ttcgtttgct ttcagcaaaa ataaatccta ggtaatcagc ctgtgattcc gccgcaagct 2239681 gcaaatcctt tagtgaccga ataccgcaat attttaatgc cggtttcttc acaacctcac 2239741 tccctaaaca aagcatggat tgctttacgc tgagaagttt gtctcatcaa tgattcaccg 2239801 ataagtacag ctcgcgcccc atgttcattg acaaatgtta aatgttctaa agaaccgatt 2239861 ccgctttcgc tgacaagcaa ggattctttc ggaacgagag atgcgatttg ttctgtctgc 2239921 tttacagatg tttcaaacgt ttttaggttt cgattattta cgccgagaat gtcgggtgtg 2239981 aacactttca atatttgttc tagcgttgat gcatcatgaa cctccactaa cacgtccatc 2240041 cccttttcac ctgcttcaag atataattca tgaaggtgta agggatcaag cacctcgccg 2240101 attaacaata tggcatccgc tccgattctt cttgattcct ctacttgaag agaatcaata 2240161 aaatcttttc taagtacagg aatcgaaaca gcacgcttta cgtctgataa atagctgttt 2240221 tccccttgaa aaaacggggt gtctgttaaa acggaaatcg catctgcctt cgcagcctca 2240281 tagtcttttg caatctgcac aggtacaaaa tcctctttaa taagcccttt tgacggcgat 2240341 gctttcttca cttcggcaat caacccgata aaccgattcg ggcttgccag cgcctcctta 2240401 aatgaacgtt tctcgaaagg ctgctctacc ggcagaacca gtgttttcac ttcttctttc 2240461 ttttgtttga tgattttttc aagcatagat ctcttcctct ttctgcttta gtcgttcaag 2240521 ctgcgcggca gcgcctccgc ttgtaatcgt ctctaacgcc agctccgttc cttccttcag 2240581 tgaggcggta attcccgccg tgtaaatcgc agcacccgca ttaaaagccg taatagataa 2240641 agcggaactg ctgcttttat tttcaaaaat attctgaatg agataagcgc tctctttcgg 2240701 agactgcacc tgtaaatctt caagtctgcc atttgtgaaa ccgaaatctt cgggtgaaac 2240761 ggtatactcc cggcgctctc cgtcctttaa ttcaatcacg tcggtcggtg ctgtaattga 2240821 aagctcatct aaaccgtcac ggcttgatac aaacataacg tgcttcggct gaaacgtctc 2240881 cagtgcgctt gccatcagtc cagctttttc aacagaatag accccaatca cctgacgctt 2240941 cgcctgtaaa ggattgctga gcggcccaag cagattaaat accgttctga aacctagctc 2241001 ttttctagta cctgctacat gtttcataga cgaatggtaa agcggcgcaa aaagaaatcc 2241061 catgttgttt gtttcaatgc tgcttttgac cttttcggga gtggtttgaa tagaaacctc 2241121 tagctcctct aaaacatcag cgcttccgct tttagaagag acagagcgat tgccatgctt 2241181 agcgattttc gcaccagctg ccgaggcaac aattgccgag gccgttgaga tattaaaagt 2241241 ggaaataccg tctccccctg ttccgcatgt atcaacaata tcaggaagtc catcgactgt 2241301 aagagcgtgt gcccgcattg ccttcacaaa acccgcaagc tcttctggcg tctccccccg 2241361 atgagcaaga attgacaata tcccccccat ttcagaagga gtcatttccg ctgccatcat 2241421 catattcatc agcgtttcag cctcaccggc agtaagggtt tttccgtcaa cgcacaattg 2241481 tagaaatctg ttcatcagct ttatcctcct tgctatgaaa catgtcttct gcaatatgaa 2241541 tcgttttcag cagcgcaccg gctttattac agctttcttc gtattcggct tccggaacag 2241601 aatcagcaac aatgccagca cctgcctgta tcgatgcaac accgttcttt acactcatcg 2241661 tgcgaatcgt aatacaagag tcgatattcc cgtcaaaccc aatgtaggca atacaccctc 2241721 cgtatgtctc tctcggtgtt ggctcgagtt cttgcaaaag ctgcatggca cggattttgg 2241781 gtgcgcctgt taaagtcccc gccgggaaag cagacatcag tgcatcgaca ggatgaaccc 2241841 cttttttcaa tcggcctgta accaccgaga taatgtgcat gacatgtgaa aaggaaacaa 2241901 tttttgtgaa ctccggcaca gaaacagaac catactctgc tactctgccg atatcgtttc 2241961 gggcaagatc aacgagcatg taatgctccg ctttttcttt ttcatccttc atgagctcaa 2242021 ccttcagtct ctcatcttca gctttgtctg caccgcgttt tctcgtaccg gcaatcggat 2242081 ggatttctaa gtgcccgtct tgaacgtgta ttaaccgttc cggagagctg ccgactattt 2242141 ctctgtctag cagtttcata taatacatat acggcgaagg attgacgatc ctaagcactc 2242201 ggtataactc aaaagcatct gcttttatcg gcacctcaaa tttttgtgat aaaacaccct 2242261 ggaagatatc gcctgctttt atatagcttt tgattttttc tacatcagcc ataaaagccg 2242321 atttttcata attagaagat actgtctcaa agctgggtgt cttgtatgaa tcagcagaaa 2242381 gaaacagctc ttttatgttt ttttggtcca tcattttttc aatgagattt tgaagctcca 2242441 gatgattttg atggaataca tccatttttt cgttttttgt ttcctctcca gtgagccttg 2242501 catattggat aaagtggacg tttttggttt catgatcata cgcaattaat gtccggcaaa 2242561 caaacagcat acacttttcc atgtctgttt ctttggtatg cgaaggaaca gaaggctcaa 2242621 tcagcgggat catatcatag cttaagtacc cgacagctcc gccgacaaaa ggaatgccaa 2242681 gctcaggtgt tttgattttg tatgtggtat tcatccagtt cagcacttct tttagttcat 2242741 ttcctgtgta aagagatttg ctgtcctgat cagcggccga aaaacggccc tgctcttctt 2242801 taattgtgag aaatggattc aggccgataa acgaatatct ggaccaagtg gatgtatcgt 2242861 ccttgctttc aagaagatac gtaatctccc tgtcaagctt ctctatcatt tgaatgggtg 2242921 tcagtgtatc gactgtgaag gtctccacaa tcggtatcgt gtggtgggac aagctgtcct 2242981 ctaaaaatgc ggaaatgttt gattggaaat tcattgctct cactccttat ggcaaggaga 2243041 atgagaagat ggcatgagag gataaaatac tatataacaa ataaacccaa aagaaagact 2243101 tcttttgggt agaataaaca taatgtctca gctcaactaa actcattctc tgctacccta 2243161 ttctctaact caactcattc taattgcttt atacacactc ttgtgtattt ctaagctgtt 2243221 cttatcgtat tacaattcag tattttttgt caatgataaa tcgggcctca atacgacaac 2243281 tttttctaaa tatacatgtc tgatctgatc ctgagggaca tctgtctgga ccgtcatcat 2243341 gactcttatg cactttttca gaccgcctgt tacgtccatt tcctgcatac atgttaccgg 2243401 tacatactgc catcctgaaa gctcgcgaac agcttttgcc gggaaaacag cgtgcaaatc 2243461 aggtgtagcc gacagaagca tttgaacaac atcttccggt tttgtatgat tttcttctat 2243521 gattttctct aacagctgtt tagttttttg taaaatttct tcttcagtat cccgttcaac 2243581 tgtagttgct ccgcgaattc cgcgaatcat catgatgtct cctccaatcg ccatttgttc 2243641 agccagctct caagttcatt tctggaaaat gtatgatcag caactttccc taattcgttg 2243701 agcacaataa actgaatctt cccgccacgg gttttcttat cattcatcat acggttcaag 2243761 agaaccgaag tttccgtctc ttttctgatt tgacttggat aacccaggct ttttagccag 2243821 ctgaccaaac gttttctgtc catttcacag cctacagtct tttcgcttat atataaagca 2243881 aactgcattc cgagggctac ggcatcaccg tgagtgatct gcccatatcc atattccgcc 2243941 tcaacggcat ggccgagcgt atgcccaaag tttaagtaag ctcttatccc ctcttctttt 2244001 tcatcctgct gaacgacaga cgctttaatt gaaatgcctt taaaaatcat gtcattcagc 2244061 tgatcattag tgatatcacg cagtgagtgg atattcagca gctcctccag aaacgctctg 2244121 tcatagataa aagcgtgttt aatcacttct gccattccgg acctaagctc tttttcaggc 2244181 agagaacgca ggaaatctgt atcatagagc acggctttcg gctgataaaa cgcaccgatt 2244241 agattttttc caagcggatg gttcacggct acttttcctc cgactgcgct gtcatgcgcc 2244301 aagagcgtcg taggcatttg gatgaaatca atgccgcgca taaaagtggc agccacaaaa 2244361 ccggcaagat cccctacaac accgccaccg aatgcgatga tgcatgagga gcgatccata 2244421 tgaaaacgaa tcgcttcact ctgcaatttt gtgtacatgt ccatggattt tgcctgctct 2244481 ccactcggta ccgtcacttt tttcacaggc catttttctt gcagcaaatg gagcatttca 2244541 tcaccataca ggcggtccac ttcttcatcc gtgacaaaca taatccttgt taaaggcctg 2244601 tttaaagagg ttaatagttc gcaagccttt tttctgatac cttgtccgat aaaaacagga 2244661 tatgacgagg aagcagtttg aacatgcagt gtcttcatta aaattccctc gacagttttc 2244721 tcatattctc cacattttct ctaatgcggt caatttgatc taatccgaat tgttcaacga 2244781 ctgcgttcgc aatttcccaa gcgacagccg cttcagcgac tacacttgcc gcaggaacag 2244841 cacagctgtc tgaacgttca atgctggcag aaaacggttc tttcgtttca atatcgacac 2244901 ttttcagcgg tttatacaaa gtcggaatcg gcttcatgac tccgcggaca acaatcggca 2244961 tccctgtcgt catgccgcct tccagtccgc caagtctgtt agtagcacgg gtgtatcctt 2245021 tttcctcgtc ccaaatgatc tcgtcatgga cttcgcttcc atttcgccct gctgcctcaa 2245081 atccgatgcc gaattccaca cctttaaatg cgttaattga cagaacagcg gcagcaagct 2245141 tgctatccag cttgcggtca taatggacat agctgcccac gcctaccggc attccctcga 2245201 caatgacttc tactattccg ccgatggaat ctccgtttgc ctttgcttca tcaatggcag 2245261 ccatcatttt tttgcctgcc tcttcatcgt agcatctgac aggagactct tccgttacac 2245321 gctgcaagtc ttcaattgac gtatactctg ttttttcagc tttaacagcg ccaatttgca 2245381 acacgtggcc cgccacctta atgccaagct cagaaagaat ctttttagct acagcccctg 2245441 ccgccactct gacagttgtt tcccttgctg aagaacgctc aagcacattt ctcatatcac 2245501 gatgattata tttaattgca ccgtttaagt cagcgtgccc aggtctcggt ctggaaatct 2245561 ggcgcttcat ttccttttct tcatcttctg taatcggagc ggcgcccatg atttttgtcc 2245621 aatgcttcca atcgttattt tcaactacga gagcaattgg cgaaccgagt gtacgtgcat 2245681 ggcgcacccc gctcataatt ttggcctggt ctttttcgat ctgcatgcgg cggccgcggc 2245741 cgtgtccttt ttggcgtctg gcaagctcaa aattgatatc ttcctccgtt atgtaaagcc 2245801 cggcaggtac accctcaata atggttgtca gttgggggcc gtgtgattct ccggctgtta 2245861 aatatctcat gacttcttct cccttcatcg cattaacgct tttaagtaag actactataa 2245921 catatttttc agcaaaaagt cagtctatct tttttgataa aagaatgtat cggctgggac 2245981 taggccaaat ttctcgggat tgaagatttg ctcggtgctg ccgacaaaaa gaactccatt 2246041 cttcttcaag ctatgtgcca tttttaaata cagctcttcc ttcgcgcttt ctgtaaaata 2246101 aataaataca ttgcggcaca cgattaagtc aaagtcttgt tcataacgat ccgccagcaa 2246161 attgtgcttt ttgaatgtaa tattcttttt gatttccgtt ttcacttcat aacttctatt 2246221 tgcgttttgc gtaaaataac gatctttcac agatagcggc acttcctgta aagaccgctc 2246281 ctgataaacg ccttttttcg ctttttccaa tgctttttca tcaatatccg tcgctaaaat 2246341 ctgatagccc ggaagacctt tttgctggtc caaaagcatg gcaagcgtgt atggctcctc 2246401 ccccgttgag caggcggcac tccaaatttt taaaggccta gaggtcttga ttaacggcag 2246461 aattgcagtc tcaagaactt cccatctttt ataattacga taaaattctg aaacattgat 2246521 cgtcattctg tccaatgttt catttaagag agcttgatcc ttttccaatg ccgcagcaaa 2246581 gtccttaaag ctttggaacc cctttttctc ataaagtgac gttagccttc tcttcatttg 2246641 tgcttcttta tatagtgtta aatcgactcc ggttaattgt ttccatttcg ttgtaaatac 2246701 gctgtatgta tccatctcta ctctcccagt ctcgctgtct ttttgtccta gtatagcttg 2246761 ttttatcagg aaattgtatt gtttcaataa aaaaatcagc ttttcagctg attttagatc 2246821 gttgggaaag gcagaggtct gatgcacact gccattcaac cctttattca ctttaatgta 2246881 aacctttaca aaacagaaca aaaaccggcg gcgttatatg ttgccggctc tgttgcttat 2246941 tttcacaatg attaatagat ccagcctgcc ataagctgct gatatgatac taattcttca 2247001 ttcttaaaga aaatgttaat ctcgcgttct gcactttcga gagaatcaga gccgtggatg 2247061 atgttttttc cgacaaacat gccataatcc ccacgaatcg taccaggtaa agcttcttta 2247121 gggtttgttt tcccgatcag ctgtctcgtc acttcaatga cattttcgcc ttcccacacc 2247181 attgcgaata caggtcctga agtaataaac tcaacgagct ctccgaagaa aggcttacct 2247241 tgatgttcgg cgtagtgttt ctcagccatt tgttcagtca ctctcattaa cttggcgcca 2247301 gctaattgta agcccttacg ttcgaatcta gataaaatgt ccccaatgag ctgacgttgg 2247361 acaccgtctg gtttcaccat gataaaagtc ttttccatca tattctccac cccatcatta 2247421 tgtatgtata ggctttcaca ctgcacaccg aaatcgtaac atctttctga taattaatca 2247481 atccggggcg gagaaatttc ttaatatcta caaaaattaa aattttcttt taccgatata 2247541 ttttgcgatg gctgcaagag acgagcgtgc gcgccctcga ggaagcgtgt ttaatttctg 2247601 aaaagctttc tgcagataca tttcgcttac tgccatagat gcttcaattg catctgtttt 2247661 tttgatttct tcaatgattg gttcaagctg ttcctgcgtt gtctcactgt taatcaattt 2247721 aagctggttt tttaatgcag gatttttcag ggcatacagc actggcaatg tgacgtttcc 2247781 ttgaagcaaa tctcctccta cgggtttacc cagctcttcc tcagttgaag taaaatcaag 2247841 aatatcatca ataatctgat aagacatgcc gacgtaatac ccaaaccagt acaatgcctt 2247901 atgaatcttc tcatcagctc cagacgcaat ggcaccaagc tggcagctga ccgcgatcaa 2247961 gagagctgtt tttcttttga tacggcggag atacgttctg agattttgtt ccatgttgta 2248021 tttgtctttg atctgctcaa tttcccctag acaaacttca acgatcgtct gtgacaaaat 2248081 cctatgggct ttcggttcgt taattctcgt catcatttca agagatcccg caagcatata 2248141 atcgcctgtg tacatcgcaa tacgattgtc ccactttgct ttgattgtcg gttttcctcg 2248201 gcgaagctct gcatcatcaa tgacatcatc atgaaccaaa gatgccatgt gaatcatttc 2248261 cagagtgacg gcgacatatt taatcttatt aatatcataa tcgccaaaca tgccagaaag 2248321 cagcacgaaa acaggccgaa tacgtttccc tccggcctgc agcaggtgaa gacctgcctc 2248381 gcttaaaagc gggtaatcgg aacgtacggt ttgttcaagt tctctttcga ttacatcaat 2248441 atcgtcattt aaaaaagagt aggccatttt aaatttcata tcattcaccc aaacatctgt 2248501 gttttcattt ccatccgata tgcgtggcag cgactccgcc agtaaacgaa tgatatttaa 2248561 catttttcag gcccgcctct tcaaacaggc ctgccagttc cttcattcca gggaaatctc 2248621 tggctgattc ttgaagccaa gaatattctt tatagctctt cgcaaacagt ttcccgaaaa 2248681 acggcataat atacttaaag tacataaagt aagcctgtct gaatccgaac atttccggct 2248741 gggacgtttc cagacatacc acctgcccgc ccggcttcac tacacgtctc atctctttca 2248801 gtacagtcaa gtaatcaggg acattgcgga gtccgaagcc aatggtgaca taatcaaatg 2248861 tatcatcatc aaaaggaagc tccatcgcat ttccgtgcag cagttcaatt tggctgaatc 2248921 cgccgtcttt tactttctgc tcgccgacac tcagcatatt ttcactgaaa tccaagccct 2248981 tgatctcgcc gcttttgcct gccgcttttg caagagcgat cgtccagtca gccgttccgc 2249041 agcagacatc aagtgctttt gcgccttcct ttacattcat gatgcgcatc gttttgtcgc 2249101 gccatttttt atgctgctga aaactgatga cagagttcat ttggtcataa tttttatata 2249161 ttttttcaaa tactccgtgt acgcgctgtt cttttgagtc ctgcataatg gtttaccctt 2249221 cttccacttt ctgatgatag gtttgatctt ggctgattgt cttcagacgg tttattaaaa 2249281 tgttctgaat aggtgaattt agaggcagaa gtgactcaat gctgtttttc gcttttttaa 2249341 aacaatcttc taatatctct tcttttgttt ttcccagctg tataaaactg ccgatcacat 2249401 ccagaaatgc atcatttccg ttcataagcc gcttaaatac aaaaaaatca ctcgacagct 2249461 ttttccagcg cgggaggttg aagtgttccg ccacacgatg gaataaagct gattcaacga 2249521 tgccgacact ttcgaaaaaa tcgttttcgt ccttgaaaga acggtcatac agacgaattt 2249581 tatgttcgtt gatttcttta atggctgtag caagcgtccg aatcatgtag atatccttca 2249641 tttcagatag taaagagtag tacagcccgc tgaaataatc gcccgcgaga acagtcaatt 2249701 ggcggttttt gttttcgtct cgttttatga ctctagctgt cgtcacttca tcatgggtat 2249761 caagggcgct ttgtacaagc atcgctgtta caatataatt ttctctgtcg ttgtttttta 2249821 tgtcggcttc ttcaaataaa gcatgaaaaa gaagaagctt atcctcatca attttcggcg 2249881 cagaaatatg cttcgctaaa taaggatgag acagcttttg ttttaatttc gtgttcagat 2249941 tggctaaagt tccgtagatg tcttgcaaaa atatcaccct tgtccccaaa ttcacattta 2250001 tttcttaatc tatgtatgag ttttatcttt tcattcgctt acgcaggtat cattatagca 2250061 taaaaaaaag aaattggctg tatcctcccg ctgtttgcga gcatttgctt ttaacagcgg 2250121 ggacagccag cttatttttt ttcgcttttc atttctccgt acgcggtttg aatcagtgcc 2250181 tctcctctga ctttaatggc agaagtatgc tctgtaaact gagcgatgat cacttctccc 2250241 ttgtcgagtt tttcggaatg gtgaaacttt gtgtctgttc ctcttgtcag gccgatcaca 2250301 ttcactccgt cctcaacggc tttaatgacg acaaaatcac ttgaatgctt ttggttcatt 2250361 tatagcaccc tctatcttta ttagtcctgg cgtttaatat gttccaatac ttctgcacgg 2250421 gcagcggcat catctttaaa aacgcctctg actgctgaag tcacagtttt cgcacccggt 2250481 tttcttacac cgcgcatcgt catgcacatg tgttccgctt caaccactac cattacgcca 2250541 tgcggatcaa gcgtttctac gatgctttct gcaattgtag aagtgatgcg ttcctgaagc 2250601 tgcgggcgct ttgcaacggc ttcaacggca cgtgccagtt tgctgagtcc tgtgaccttt 2250661 ccgcctcgcg ggatatatgc aacatgtgct tttccataaa agggaacaag gtgatgctca 2250721 cacatagaat gaaacgctat atcttttaca agaacaagct cctcatggtt ttcaccgaag 2250781 atagtctgga aatgttcttt tggatcttca ttcaagccgg agaatacttc ggcatacatc 2250841 tttgcgactc ttttcggagt atcaagaagc ccttctctat tcgggtcttc tccgatcgct 2250901 tctaaaattt gacgaacagc ttgttcgatt tgctctttat taacttcttt catgttctat 2250961 gtcctccacc aatgaataca tttaatttcg attctagcac atatgccccg ctaaaagcaa 2251021 agtgaatgcc ctgtcaggaa gcccatgctc ttgaaatatg aaaagcccct tagaaagggg 2251081 cttttctgtg aagaaataaa gtgtatgtaa gctagatgca tacacgatct atattcacaa 2251141 ttattttccg gcaactgcgt ctttaagcgc tttacctggt ttgaaagcag gtactttgct 2251201 tgctggaatt tcgatttctt cacctgtttg aggattgcgt cctttacgtg cagaacgttc 2251261 acgcacctcg aagttaccaa aaccgatcag ttggatttta tcaccgtttt taagtgcatc 2251321 taagatcgta tcaaaaacag agtcaactgc ttttgtagcg tcttttttag acaattcgct 2251381 tgcttctgca accgcattga taagttctgt tttgttcatg cctttcacct cctcccaaaa 2251441 ggatacattc agttcgttta ttatcatttc ttcacagttc agtctgattc taaacctgtc 2251501 tcagaaaaaa atgagagcaa gtaagagaaa gacaattaaa cggcttttta agaaaaactg 2251561 cactctgagg aatgtttgtc caacaaagtg aagaatttct gtatgtagag taacacatat 2251621 aaaaagccat atcaagcatt ttaaagcgtc aatcccttgc tcgtcaagga tttaaggtga 2251681 tttaccgaac gaatattcct ttttttcctt ttttcatcct attccttgat ccttttccat 2251741 tattaagagc aaagaaaaaa gacctcccat tctataaaga ggtctaccgg tattacagga 2251801 tgatggcgat taagccgcca gagccttcgt ttatgattct ttctaatgtt tcttttaatt 2251861 tataccgtgc gttttcaggc atcaatgaca gctttgcctg aatcccttct ctcacaattg 2251921 agctcagcga ccttccgaag atatcggaat tccagatgga gagcggatca tcctcaaagt 2251981 cctgcattaa atagcgtaca agctcttcac tttgtttttc cgttccgata atcggggcga 2252041 attcgctttc gacatctact ttgatcatat ggatcgacgg agcgacagct ttcagcctca 2252101 caccgaatcg cgagccctgc cttataattt ccggctcatc gagactcata tcagctaaag 2252161 caggcgctgc aatgccgtat cccgtctgtt tgaccatttt taaggcatca gacacttgat 2252221 catattctgt tttcgcatgg gcgaagtctt gcatgagctc aagcagatgg tctcttcctc 2252281 tgatttcgac gcccacaact tcttttagga tttgatcata tagatgatca ggcgcgtaca 2252341 aatcaatttc tgccacccct tggcccagct caattccggc taatccggca ctttcaatga 2252401 attcaaactc gctgaattgg ccgacaaccc tgtctacgtc ccggagccgt ttaatatcct 2252461 taaccgtttc cttcacggac tcctgatagc tttcacgcaa ccaatggttt tctttcagca 2252521 ccattaccca gcttgggaga ttgacattca cttctagcac cggaaactcg tagagggcct 2252581 ctctgagcac actcagcaca tctgattccc gcatgctctc tacactcatt gccaataccg 2252641 ggatatcata tttttcgctt aaatcctggc gcatggcttc cgtttccggg tgatacggcc 2252701 tgactgagtt gatgaccata ataaaaggtt tgccaacctc tttcagctct tcaatgactc 2252761 tttcttcagc ctctatatag tcacttctgg cgatatctcc aatggtgccg tctgtcgtaa 2252821 tgacaactcc gatggtcgag tgttcttgaa tgacttttcg tgtgccgatt tcagcagcct 2252881 catgaaatgg gatcggttct tcgtaccaag gcgtattgat catccgcggc ccgttttcat 2252941 cttcatatcc tttagcgccg ggcactgtgt aacctacaca atctactaat cttatattca 2253001 catcgagtcc gtctgacaca tgaacagaca tcgcctgatt cggaacaaat ttaggctctg 2253061 tagtcataat ggttttgccg gctgcgctct gcggcagttc atcctgcgct cgggcccggt 2253121 ctgcttcgtt actgatattc gggagcacca caagctccat aaatttttta atgaacgtgg 2253181 attttcctgt acggacagca cctacgactc ctaagtatat atcgcctcct gttcgttcag 2253241 cgatatcctt gaaaatatcg accttttcca agtgatcccc tcccggactt cctatccttt 2253301 tcaattttat taagctcttt caatcaaaca caggacacta tatgtgtatg acgttgtcct 2253361 atttgaatat gacatcttta gaaaatttct catcctcaat ctattaatat aaaaaaacct 2253421 ttctccctat ttgtatgcaa gggagaaagg ttcattcctt tttcatatca ttttctaaaa 2253481 aaacaggttc ctgtttgtca tttaccgtat attttacaga aaacgcgggg acaaaggggg 2253541 tttcatgcca aatcatatcc tggatttcag tcccgggttt aaacgttttt ttgctttttt 2253601 tgaggcaaga agccagctca gtccggtaat cggcatatat ttctccgtct ccgtcaatca 2253661 taagcggcaa ggaattccct gagattgggc ttgtcactgt aagagagctg ccatccccaa 2253721 gcttcttctc atcgagtgta aataaatcac gagatagcac atccttgtaa ggcggatatt 2253781 gatgctcctg acgatacatt tggatgcgca atttcacatc gcgaattttt tctgccatct 2253841 ttagatcaat taatttaaca gtcggatcgt tctctacgtc aacaagcacg tattgatagt 2253901 ctcccccgct ttcaaatgcc gtacttggag gttcagctat gtatcttggc gctaaccggt 2253961 taaagtctat cggatatttt tgatatagcg gtgtcgacat atctttggtt tgaataggaa 2254021 gcagccctcc atttgccttt tgaaattcat caacagcaga ttgaacctgc tttagctggt 2254081 cttgataagg aatggcatgc acactgcttt tccgttcatt tggatataaa catccggata 2254141 aaaacacgac tgccgcaaaa atgattgcgc acttcagttt acccatacag cacttccttt 2254201 tacagcttta ttcattgaca gggccgctaa aaaccacgac aaacacaata attccagata 2254261 tgagcataca catgtatgcg aatgatgaaa tcgcaatctt caaaaaacgg ttttggcact 2254321 taaagcggct taaatagatg gaagctacag ccagaaacat cagacccatg gaccctagag 2254381 caaaccacat tttcatcaat gccagattca atgacgtgcg cctccccgat atgtaagata 2254441 taagcgttat attatatttt aatatacagc gccggaaaag atcaaccaga ttttccatcc 2254501 attgatagaa caaaaaaact gaagcaaaga gggggacctt cgcttcagtc aacttgacta 2254561 tattcacctg cacgtttaag aaacactctc ttggacttcg atgctatagt atgcgacttg 2254621 gcatacagat gcatcctcta ttgcctaaat cggcaaaatg tttcaggaga tcccaagact 2254681 tgggtgttct tctgtttttc gggctttcgt tcaattaaga tatgcgattc accatttgat 2254741 tgacactttt acttcacttg attttcaaac gtatttacca aatcctccat ctcgtgggtt 2254801 ttccctctcg ccattaaaga ttcaacagcg gtttccactt tttgtccgtt gaataggacc 2254861 tgatggagag cttctgtaat cggcatttta acatcatatt tcttcgaaag ctgataagcc 2254921 gctttcgtcg tgcggacgcc ttcgactacc attcccatct cttcaagaac atcttcaagc 2254981 ttgtaccctt ttccgagcaa attgcccgca cgccagtttc tggaatgaac acttgtgcac 2255041 gtcacaatca gatcgcctac tcctgtcaat ccagagaacg tcaagggatt tccgcccatt 2255101 ttcgttccga gtctcgcgat ttcggcaagt ccgcgtgtaa tcaaagcagc tttggcattg 2255161 tcaccgtacc ctaaaccatc tgtaattcct gcagcaaggg caataatatt ttttaaagcc 2255221 cctccgattt caactccgat aatgtcagga tttgtgtaca cccgaaaatt gtgattaata 2255281 aatagatcct gcacctcttc tgctgccctc atgctctttg aagatgcagt aacagttgtg 2255341 gggtgccgca gccctacttc ttccgcatga ctcgggccgg aaaggacaac gatatctttt 2255401 ctgacatcac tcgggagctc aatttccata atttcagaaa tgcgcagaag tgaatctggc 2255461 tcaataccct tgctgacatg aacaaagact gcctttttcg ttataaaagg gacagcctgt 2255521 ctcagcactt cccgaattgc ttttgtcggg accgcaacga taatgacatc tgcgtctgaa 2255581 acagcctctt tcatatctgt tgttccttta atggatgtag acagcttaac attcggcaaa 2255641 taatctttgt tttcatgcaa ctcattaatt tgatgaatta aatctgcacg gtgagcccac 2255701 acacacactt catttccatt atcagttaga actaaagcca gtgctgttcc ccaactcccc 2255761 gctccaagca ttgtgacttt tttcatgttt gattcacacc tttttatttt ctagctcttg 2255821 caaatatttt gattggtgtc ccctcaaaac cgaacgcgtc tctgattcgg ttttctaaaa 2255881 accgttcgta tgaaaaatgc atcagttccg gatcgtttac aaacacaacg aagcttggcg 2255941 gctttaccga cacttgagtc gcatagtaaa ttttcaaacg agaaccgtta tgagtcggtg 2256001 tcggattcat tgccacagcg tccatgatga catcatttaa gacgtttgtt tgaactcgaa 2256061 gtgaatgatt ttcactagct ttgataatcg caggcatcag agtatggatc cgttttttcg 2256121 ttaaggcaga cataaatagg attggcgcat aatccagaaa ttgaaaatga tcgcgaatat 2256181 tttcttcaaa ttctttcatc gtgctctcat ctttgtcaac agcatcccat ttgtttacga 2256241 cgatgacgac ggccttgccc gcttcgtgtg cataaccggc gatacgcttg tcctgttcaa 2256301 taatgccttc ttcgccatcc agcacaaccg ccacgacttc tgagcggtca atcgctttta 2256361 gcgcccgcag tacactatac ttctcagtcg tttcatagac tttccctttt tttcgcatac 2256421 ctgcagtatc gacaatgaca aactcctgct ggttgtaagt aaatgacgta tcaacagcat 2256481 ctcttgtcgt tccagccacg ttgctgacaa taacgcgttc ttcgccgagc atcgcattca 2256541 caagtgaaga ctttccgaca tttggacgtc cgatcagaca gaattgaata acttcttcat 2256601 tgtatttcgt ttcaggaatg tttttaaaat gctctgcaac ggcatccagt aaatcaccca 2256661 gtccgagtcc gtgtgttccc gaaattggat acggctcgcc aaagcctagc gaataaaaat 2256721 cataaatatt cgctctcatt tctgtgttat ccagtttatt aaccgctaaa acaacaggct 2256781 tttttgtgcg gtacaaaatt ttcgccactt cttcatcagc agctgtcacg ccttcacggc 2256841 cgttcaccat aaaaataatc acgtccgctt catccatggc gatttcagct tgctggcgaa 2256901 tctgcgctaa aaacggctca tcaccgatat caataccgcc cgtatcaatc aaattaaaat 2256961 cataattcag ccattcagcc gagctgtata tccgatccct tgtcacgcca ggggtatctt 2257021 ctactattga aattctttct cccgcaatcc ggttaaagat tgtggatttt cctacatttg 2257081 gtctcccgac aatggctacg acaggtttac ccatagtacc cttcctttca atccagccgc 2257141 tttcattttt acataaattt tcaaccggtt attaaaatca tttcattcac ttttatgaaa 2257201 agaaaccctt cagaggaagg gcttaactca tttattatat cagtttttac tgggatcaca 2257261 actattctta aaaatgtttc acgatcaaat acacgtcatc tccgattctg tgagctattc 2257321 catcaaggat cgcctcaaga tttttagcga aaagctccat ctccttttgg tcattgcaaa 2257381 aaaagacagg tgctccccct gcaacccgat ttcgatttgt cgtgattaca gacaaaatca 2257441 ctttcgtaag agattcactc atcctatcac cttatcctga ttcttgataa attcagtcgg 2257501 cattctaatc gcattttcca gggttggaac attgctaata atttgaacag ccgtttcggg 2257561 atggtgaatt tgcgggagaa caaatactgc cactctccca tcatttaaat cccgttttgc 2257621 aattggtgtc aaagatggct ctcctgaatc ccgataaacc ccgagcacat tggaaacatc 2257681 aaataaaatg gcctgacgct gccctaaatt tgctatcgtc gctgctgaat taaagttttt 2257741 cggcgtcaaa ataaagccca tgccatgctt taaaatcagt tcctgtttct ctggaagccc 2257801 gatattcatc atataaatat tatcaacaaa cagtcccgga ccgtcaaagc gcggctttat 2257861 gtactcgata tctacaatat ccttcaacac actgcccgac ataaacttca tggccagtaa 2257921 aaaacaaacg acagccgcta tgactgcagc ccagatggat aaaaacacat acgcagaggt 2257981 tgtcaaaagc gctgtaaaga tcacaatata atttctgctt tcaaacgcaa tggcaatccc 2258041 ctcaatatat gtgcttcccc ttgagacaag ttcatacgaa tccatttgcg tcaatgtgtt 2258101 ccgctccatg tttcggacat ctctaaattg cgtcgctgcc aatgttaaaa atgtgatggc 2258161 cgtaaattcc tcctgcaaaa gcgccggcat aataattgca cctaaaccag ccgctatcaa 2258221 ccccagtgcg atgtgaatca ctttcccatg aacataggtc ggatactggc ggtaatccgt 2258281 tttcagcata taaagccttg tcgcaattcc ggcaatgacc ccagcaataa tcggatagat 2258341 gtaatcactc atgacatttt ggtagctcct ttgtttgatc ttttgctttt ctgaccaatc 2258401 tggcttgcga ggtgttcgta tttagatatg ccaaacagca atatcatccc cgcagaacac 2258461 gcattcagcc attgaaagcc gccgacagcc atagccccgg ccaacttctg gatcacaaat 2258521 gaatacacca gttcgccttg gcacatccct aggacaaata agacaagctg cttctcaaaa 2258581 ttcctttcaa cagaagctgt taaaagcact attaatataa cagcagccca ctcaggtttt 2258641 atgatgaacc aaaccgggtc atataatgca aaaagataaa caaacgcata cgcggcaaca 2258701 agcgtcagat agaccatgat gtaacgaaaa cgatacattc ccaaataccc ggcatagaca 2258761 catccgcaaa cgaaaaacat caaatatgca gcattcaggg aaaaatataa agcgatgtca 2258821 tgtatgctta gaataatatt agttaaaata aagacagaga cggcaattcg tcttttcgtc 2258881 ttttcaaaaa taaatgttgt cagaacccac agaaaccaca ttgaccaata gtaataaaat 2258941 tgttccattt tacttcctcc atattcccag tatggagttc aagcacattt tttaaacaat 2259001 cgatctcaca ttaaggagta tgatcatggg aaaagacaga caagagaaaa aactcaaagc 2259061 ttcaggcaga gtcgaatcag atcgcgacca gtccattcac tatgacggag cgacaagcct 2259121 tgaacaaaac ggaagattca aaaagcgaaa atcataatac aaaaagccca aaccacatat 2259181 ggttttgggc ttttatcatt tatcgcacac tatagcttga tgtattgacc cctctctctg 2259241 tgagccaatg atgggtttca cctttgatca caaggggcgc cttttgtaaa tcggcaattg 2259301 ttctggcacc cagcacggtc ataatcaact ttaattcctc aaggatcagc tgaatctcct 2259361 caagcagtcc ttcctcaccg ctgtcagtca gcgcttttaa aaaatgccct gccattccgg 2259421 tgcaagaggc ccccagcgca attgcctttg ccacgtcaag cgcatcttgc agaccgccag 2259481 aggcgatcat ggtgcttgca ggaaactcag agcggatttc cgccaaactt gcagctgtcg 2259541 aaatgcccca cgaattaaaa aaggagattt gccgctgtct tcggagattt tcgattttcg 2259601 agaaatttgt tcccccgtaa ccgccaatgt caacagctgc agcaccagct tcatacagct 2259661 ttcctgctga tgctttgctc ataccgaagc cgacttcttt cacaatgacc ggtacactga 2259721 cccggctgca aatttgttca atgcgtttca atgcgccgct aaagcttctg tccccttcag 2259781 gcatcacaat ttcctgaatc acattgaggt ggatctgcag tgcgtttgct ccaatcatct 2259841 caacggcttc ctttgcctga gcagccgttg cctcgcttcc caggttggca aaaatcagcc 2259901 cgtttgggtt ttcctttcga acaatttcat aggaaagacg ctctgatgga tcttttaatg 2259961 ctgacatttg cgatcccaca gcaaggggaa ttccagcctg agaagccgct cgcgcaagcg 2260021 atttattaat ctcatatgta agttttccgc cgccgccagt cattgcattg ataaaaatcg 2260081 gcgaactgct tgaaagttcg ccgatttttg tggaaatatc tacttgttct aatgcaagat 2260141 cgggcagact gacgtgaaca aacgtaatat catcaagacc tgtttcccgc ttctggccga 2260201 tggacaaggc atgattgatg tgttgtcttt ttcgttctgc tcgagtcacg tttatcacca 2260261 attattttag tttattcagc ttatctccga tcagatctcc aagctggaag ccagtgcttg 2260321 tttcttcctt cgcttgatat tgacggtaat cttcctggtc agctttaggc gtttcttcaa 2260381 gttcacgcat gcttaatgaa atgcgctcct cattttcatt cacatcaaga accttcactt 2260441 ttacagtctg tccttcttca aggacttcat gcggcgtgcc gatgtgttta ttggaaattt 2260501 gagaaatatg aacgagacct tcaacacctg gaaggatttc aacaaaggca ccgaagctta 2260561 caagacgctg tacagttcct tcaagcacat cgccaggctt cactttttcg ccgatttggt 2260621 tccaaggtcc aggcagtgta tctttgatcg ataaagaaat acgttcatta tcacggtcaa 2260681 ccgataacac tttcactttt acttcttgtc cctcttcaac aacgtcagac ggcttctcta 2260741 catgagagtg ggaaagctgt gaaatgtgta caagtccgtc gatgccgcca atatcaacaa 2260801 acgcgccaaa gtcagtcagg cgctgtactt tgccatcaag tacacttcca acttcaagag 2260861 actgaagaag ttcttgtttt ttattcgctt gttcactttc aacaacagca cggtgtgaaa 2260921 ggatcacgcg gtttttatca cggtcaagct ctacaacgag cagtgacagt gtttttcctt 2260981 tatagtcagt gaagtcttca acgaaatgtg cttcaacaag tgatgccgga ataaaaccgc 2261041 gaacgccgat atcaacgaca aggccgcctt tcacgacatc tttcacttca gcttcaaaca 2261101 cttcttttgt ttcaaatttt ttctcaaggt cttcccaagc gcggtctgca tcaacagcac 2261161 gtttagataa aatcaaagca tcgtcttcca cttttgttac tttcaggtca agctcgtcgt 2261221 ctactttaac aacatccgat gctttctcta catgaagact tgataattca ctgattggaa 2261281 taataccgga ttgtttgaca ttgataattt ctacatctac atgtttgtct tctacctttg 2261341 tcacaatccc tttaactaca tctccaacct ctggcacttg aacatcaatt tgattcattt 2261401 cctctgtcat ttgaataacc tccttggtcc aaacctacac agcttaatta aaacggtttg 2261461 aaagctgaac atataacatg cccgctttta gccgaatatg tattaaagaa tcatccaaaa 2261521 aagttttttg aatgatcaat aaaaagtttt attagtatta acttctaata aaaggacagg 2261581 tttgtcaagc aataacattc tatcttcgtt gaaaaattca aaaaaagtgg catttgccat 2261641 cctcagcggg acttttgctc cacagcctcg aggattttat cagctacctc ttgaatggaa 2261701 agcgatgtcg tgtcgatttc aagagcgtct tctgctttac gcagcggaga tacttcgcgc 2261761 tctgaatcaa gcttgtctct tcttgcaatt tcctcaatta atgtttcgta gttgacatca 2261821 aagccttttt tcacattttc ttcataacgg cgtttcgctc tctcttccac agatgccaaa 2261881 agaaagattt ttacttctgc atttggcagc acatgcgtcc cgatgtcacg accatccatg 2261941 acgacgccgc ctttttcccc aagctgctgc tggcgtttca ccatttcttc tctgacactt 2262001 ctgtgcttgg ccgcaattga aacttggttg ctgatttcat ctgttctgat cgcctcagtt 2262061 acatcggtgc cgtttacaaa cactttttgt ccatcttttg ttgtaatcag ctcaatgtct 2262121 gtccgcttta gcagctcagc cagtttttct tcatctgtca gatcaacgtt ttcctgtaaa 2262181 gccgcgtacg taatcgcccg atacatcgct cctgtatcaa tatatatgta cgattttttc 2262241 tcagccacaa ttttggcaac ggtgcttttc cccgcagctg ccgggccgtc gattgcaatc 2262301 gataatttct tttccataat tcctctcctt gctcttttct cctctaagga ttgtatcacg 2262361 aactttatga aaaagggtga aaaattgatg aataattaat gtttgaaggt ttcaatccta 2262421 ttgttttcct ccattttatc caccccttca tattgaatca cttttgatac gtatggttca 2262481 atatgctgat agtgaaaaag aaattggaca ccaagtaaaa tgatggcctg aatgaacaat 2262541 aatttgatca gcagccgttc aaatgttttc attggagcac ctccattaca aatagtatgg 2262601 aagtgtttgc cgatgtttat tccattcggg cctttcttct cttatttaac tggcgcctga 2262661 tgcagtattg aagcaaagcc tgctggtcac ctgctgcaat ttctgaatac tctaaagtca 2262721 tttttcgttt ttctgacttg gggtcattaa agattcgtct gacaactgct tctgtttcta 2262781 tttgacgtgt gtgctcctct tcaggaagac ggatgatcag gcgcaatgat tcccccgatt 2262841 gaaaagaaag gccatcagct aaaaccacgg cgatgccgcc tgcactgatg ttataggata 2262901 gtgtgcggat ctcttcttca tttcccggct gaatttgcac atctaatacc gcatcagttc 2262961 ttacatattg gcggcgctgg attcttttca ttttttcacg gggaggcatt tcaagacaga 2263021 tcatttgaag tttgtccttc actttacctt ttatacggct tataaagcga taaggaactt 2263081 cgtcttttcc cacaaactct accgttactt ccatatcgtt atgtaaaatc acagttcgcc 2263141 ctgtaactac atcaacagga tacgcgatca aaagttcatt gttttcgatg ctgaccgcct 2263201 tgctttttgc ctttttcaat tcattttctt ctatatattc taaaagtaca ttttctccaa 2263261 tctctatcat tgacttcact ctttcgcatt caatatactc acgtttttat taaagcacgt 2263321 aatgaaaaaa aggaaaagac atttagtcct ttcctcctgt ttttataggt ctttatatat 2263381 aggttctgca ttttttagtt tttcaacctt ttcttccgat ccgtctttgg cattgatata 2263441 cattctgaat gtgtcatttt caattgtccc aagcatttcg tagcataaca cttcttgacc 2263501 tagttcattt gtaatcaaag cgagccttgt ttctctcact tgtacatttt tatttaattt 2263561 agactttgcc tctgcttcag taattgcagg cttaggtatg gttctttttc tgtgagatgt 2263621 gaggaagtct cttgctgaaa agccgacaac ctcaccgtca tccaaggcca ctttcatacg 2263681 aattgcctcg gggtacatcc ggactttatt ttcaacagga acatatgaaa atacaccgat 2263741 tttatcatat tgggcacttt catcaatttc caaatcatct gtttcaaatc cgtttttctt 2263801 taaaaatgca agcgctcggt tcgatccgtc atttaaactg attttctgat ctttcacttc 2263861 tctgttttgg atcaagtata ccggatgccc gcccttcttc gtaatatcca tataaatcac 2263921 tgctttatgg tctgggtctt tcatgctgat gctatataca tcgcgatttg ttttttttcc 2263981 gctctttacc actttaattg aataattgtc atctggggca aagcgctcag caatttgttt 2264041 tgcttcctgt tcggaaattt gttttccctt cagatggctg aagcctttct cttctttttt 2264101 cgtactggtg aaactcgggc caagatcagt gccagtggag aatgcaccaa catttttttc 2264161 gactgtttta aagctgttga taatcgtatt atcactttgt ttttcgtcag aagccagagc 2264221 catttctacg tccatccagc gaaggttttt gctcatgaca aggtgctgaa catgacgcaa 2264281 ttcattttgt atatcttcgg actgctgata tagcttattt agtgatgtat actcgttttt 2264341 atcaagcggc ttttggtcca aatctctgac tgacgtttta tagctgaaat cgccgatctt 2264401 tgataatagc tcttcagttt tattaaacgg cattaatgta agcggcagct gactgacgct 2264461 gttatgagct tctgatgtaa tcctccacac atcgatcaat gcaggcgaca gtgatttttg 2264521 gctgttcatg gcaagtgttg ttccgatttt atcatgaagc tgatccacct gataggtaag 2264581 ctcatgaaac gcccgctgat agttattttc agcatgaaga agaactgcgt ctttttcctg 2264641 gtgttctttg tatccccagt agcctgtacc gactattgca ataccaagca cggcgattaa 2264701 aattcctctg atcatttatc acacctcttt ttatgctttc tcatatctgc tactcacaga 2264761 aaatgtgttt accgattctt ttaatctgcg gacgccccca aatccacgga cttgtagccg 2264821 tatccggatt aaagtagtaa agtgcttcct ctgatgggtc ccagccattg atggcatcca 2264881 gcactgcttc tcgtgccgtt tcattcggct gcatgtaaat ttgtccgtcg gctactgctg 2264941 tgaaggcaag cggctcaaaa ataacccccg ctactgaatt tggaaataac gggctgttca 2265001 aacggtttaa aatgactgct gcaatagcaa cctgcccctc gtacggctcg ccccgggctt 2265061 cgccataaac cgcttgagca agcagcctga tatcgttgtt ggaaaatcca ccaggcatgt 2265121 tcgctgctac cgcatcctgt tttcttgctt ttgctggtgt attgttttgc tgtttattcg 2265181 cattcgcttt aggcttctgc gttgtttttt ccgcaggctg tttctgccgt gcttctgctt 2265241 gttgtcttgc cttttgtgtt gctgcttttg atggtttcgt ctgatacttt agcggaattt 2265301 ttccgtaatg cgtgaatgta ttccctttat tgagctgttc catgacatat tcacgatagt 2265361 attttgattt acatattaag gtttgctttg ttttagctcc tacaaggccg tcaacctctt 2265421 ttaacccgaa ttgatcctga aaatttcgaa ctgcccagta cgtcccccat ccataaaccc 2265481 cgtcaatttt tccgttataa tatccgttgt attgaagacg cgcctgaagc tcgaccacat 2265541 catcccctgt tgcccctctt tgaatgacct gattcgaaaa ggcagagatc gtttcagtat 2265601 taataaacgt cgttattgta aaggaaaaaa ggatgagaca tgccataatc gatcctttgg 2265661 acttcatctt ttcaagcctc ctactgcaaa tttttaagtg taatcgtatt ttctgtaacg 2265721 aggttatttt tatacactct ttccttgtta tccctcagaa cataaaaact gcacacaaaa 2265781 aagccgcacg gttgctgtgc ggcttctata cttgcatcat attaacggaa cgggcttttt 2265841 tcgctttacg caaaccaaac caccataaaa ataccataaa tggaagcata taataaatcc 2265901 aattgctaag cgctgttagg ataaaatcat atgatccatg caaaagggat gggacaacta 2265961 aagaaagagt aagccacttt acacgcgcct tatcagcgga aaaacgggct tttccaaggt 2266021 aaaatcccat tataacgcca atcaaggcat ggcatgaaac aggcagcagc gccctgacaa 2266081 acgcatgctc cacgccgtgg ccaattaaat aaagaatatt ttcgagggtt gcaaaaccga 2266141 gtgatacact tgcaccgtac acaatcccgt cataatgctc atcaaagtgg gcgtgcgggt 2266201 aaacactgat catcagtata aaccatttta atgattcctc caaaaacccc gaagataaaa 2266261 aagaaacgaa aaagcttccg cctcctacat tctctttttc aagtacatac tggataaaca 2266321 tgatgggaaa tacaagaaca accccgagaa aaaacgaccg tagcaccata tgtacaggtt 2266381 cattatcata ctgatctttt aaataaaaat aacttaataa cgcgatgccg ggggcaattc 2266441 ctgcagagat gattgcaaac atcaggcaac ctctttcctt tatattccta catctatcct 2266501 accatgttgt ttaaaatttt acatctgtct gcacttaaaa aaacaaaaag agcatacgaa 2266561 tgcatcatat gctcctcatc tttaatggtt ttctcttttg gcgatttccg ctgcgatatg 2266621 ccccccgtga aacctgccgt tttcaataaa tatttcattt gcattgtttc ccgcagcaat 2266681 aacaccggca ataaagacac cttcaacgtt cgtttccatc gtttcttcgt tgaaaaatgg 2266741 acgccctgtt tctttatcaa tttcaacacc aattttttca agaaattgat gatcgggatg 2266801 atagcctgtc atggcaaata caaaatcatt tttaatggta atgagttctt tctctccgga 2266861 gcgaaacaca acttcattct cggtgatttt ttcgacacaa gctccaaatt ccatacggat 2266921 tgtaccgttt ctgacgagag cttcaaattc cggcagaatc cacggcttaa tgctcggaga 2266981 atactcattg cccctatata aaactgtgac acgcgcccca gatttcacga gttcaagggc 2267041 ggcgtccacg cttgaatttt tcccgccgat gacaacaaca tctttatcaa aatacgggtg 2267101 gccttcttta aaataatgaa atactttcgg caaatcctca ccgggtacgc ccatatagtt 2267161 tggatgatca taatagcctg tggcgatgat acaatatggc gtcgtgtagg tctcttttga 2267221 cgtctcaata acgaatgtgt tattttgcgt tttcgtcact ttacgcacca tttcaaacgc 2267281 attaacacgg atgtttttcc gtttaacgac ttcccggtaa tacgataaag cctgaattct 2267341 gacaggcttc ctgttctctg taataaatgc cacatctccg atttcgagct tttcacttga 2267401 actgaaaaag gtttgatgcg tcgggtaatt gtaaatactg ttaacgacat tgcctttttc 2267461 gatgacgagg gcatcaatgc caatttgttt taggtgaatg gcagcagata gtccacaagg 2267521 tcctccgcct ataataattg ctttttcttg aatcatttct gtcaactcct gcgattggca 2267581 tttcacttca tattttctat ttccgaataa aaaaatctcc tattttatca taggagattt 2267641 tttattttta tgcaaatcat caacttatat ccagcctcta aaacgcgaag cttcagccat 2267701 tttgcgaacg ccgaccatat atgcagcgag cctcatgtca attcttcggt tgttagccat 2267761 ttcgtaaata ttgttaaatg atttgaccat cattttttct aatttttctt ctacctcttc 2267821 ttcactccag tagaagcctt ggttattctg aacccattca aaataagaaa ctgttacgcc 2267881 accggcactt gccagcacgt ctggtacaag cagaatgtcc cggtctgaaa gaatttttgt 2267941 tccttcaagc gttgttggtc cgttcgctgc ttcaacgaca attttagccc ggatattatg 2268001 ggcattttct tctgtaattt gattttcaat cgcagcagga acgagaatat cacaatccag 2268061 ctccagcagc tcttggttgg taatggtatc gttgaaaagc tttgttacgg taccgaagct 2268121 gtcgcgtcgg tcgagtaaat aatcgatatc aaggccttcc ggatcataaa gtccgccata 2268181 cgcatctgag atgccgacaa cttttgcccc cgcatcatgc ataaattttg ccaaatagct 2268241 tcccgcgttt ccgaagcctt ggacaacgac acgcgcacct ttaatatcga tgcctctctt 2268301 cttagccgct tctttaatac agatggtaac accttttgct gtcgcagatt ctctcccgtg 2268361 agatccgcca agcacaagcg gtttgcctgt aataaatcca ggcgaattaa attcatcaat 2268421 tcttgaatac tcatccatca tccaagccat gatttgtgag tttgtaaata catccggtgc 2268481 cggcacgtct tttgtcgggc cgacaatttg gctgatcgct ctgacatacc ctctgctcag 2268541 acgctccagc tctctaaacg acatatccct tggatcacaa acaattccgc ctttaccacc 2268601 gccatatgga agatcaatta tgccgcattt taaactcatc caaattgaaa gcgccttcac 2268661 cgccttcacc tctttttctg ttacgttcgg gtgaaaacgt atcccgcctt tcgttggacc 2268721 gacagagtca ttgtgctgcg cacgatatcc tgtgaaaatc tttactgaac cgtcgtccat 2268781 acgaacaggt atttttaccg ttaataatct catcggctct tttaacaatt cgtatacctc 2268841 ttcgggatat cccaattttt ccagagcctt atgtattacg gtttgggttg attttaatac 2268901 atcaagtttg tcctcttctg tatgaccggt gtttcgatcg gctgccattt gagttaacct 2268961 cctagaatct tctgtttctc acatgctccc tttcagagaa tagtatacac cttcatatga 2269021 tctgtgcata gaataaacgt tatgtttttc catgtttttt aacgaaaaaa aactgctgaa 2269081 atcagcagtt ttccgttgca ttcttatgaa aaatgagttt gtatcgtttc tacggcatta 2269141 ccgtccataa tgagcttacc atactcttgc aggcgataaa tcgttaaagt tgtcggattg 2269201 ccgtattcag ccagaaccgc cacaacccct tcagccgtat gtgaccctag atcttcaagg 2269261 cttaaaaagt actgcccgtc atagtggtag acagttcccc ctgtgatacc gattcgctgt 2269321 aagctttctg aaagctgaat gatatcttca aaggaatgga attgatatat gatgtccgcg 2269381 ctttcatcaa gcttgacttg catttcgatg taatcatcat catactcatc gtcttctgaa 2269441 tcggcgtctt ggttctttgt tacaatcacg accatccctt gtgcttggag agaatacact 2269501 tccactgcaa tcggtccatt cgcttcaaag ccgagctctg tatttgcttc attcatcata 2269561 tctttaaata actggtggac tttaaatgag tccttccaga ggtcttcttt tgtcaatccc 2269621 cggtctgtca aatcatcgag ggttaaaaag attttgatct tattataatt cagacgctca 2269681 agccgcataa cgttccctcc tgcctctact tgcacacaaa tcatataaca cattatatga 2269741 gatgatgagt cataggttct taattgttat cagtttacac tgagttcact agtaagacaa 2269801 gcacaatgca gtttttattg ccatacggat ttttgctttt tagaagttat tctggcccgc 2269861 aaagagtcac aatgtgagtt tcaggctcag cacctaaacg aagaggcact tttgtcgtgc 2269921 cgtagccgtt gctgatcaga tatgccgcgt ttttaacaat acctgttttc cccagttcat 2269981 aaggaccgaa ttttccaaac ctgatctggc ctccatgggt atgtccgctg agtatcacat 2270041 caataccgtc atcttcattg atttgttcat gaatctccgg attatggcaa accagaatat 2270101 tcagctggct ttcatcaagt tctttgatgg cttcctcata atgatccatc tccatcctga 2270161 tatcatcaac ccccgcaatc gcaatcgtat gcccattgta tgaaaacggg actgactcat 2270221 ttctcagagt gatgacgccg tgcgctttaa atatggaata cagcttatgc tgcctgactt 2270281 cataatcatt attcccccac acaaacacga tagggacccc gaaatgtacg agccttttga 2270341 tgttttcctc gattctcgca ctgggcaccc cgccctcagc taaatcaccg ccgattataa 2270401 ccaagtgggg ggcatggctt cgcgcttttt ctaaaaggtc ttgatcgatg agacgtttgt 2270461 gaatgtctga aataaaaaag attgtcagag gcggcttgcc cttcatcttt gataaaggaa 2270521 acgtatgtgt cttcaaatga ttgccttttg ctgttgcata catttttgcc gtcattgccg 2270581 ctgccgcaac agttagtaca ccggcaattt tcactgatag cttcataaaa aactctccat 2270641 tctttttaga acttatcaat aagacggaca ataaaaaaag acgtttctat cgtttgagaa 2270701 aacgccccat tttatttact ttcaaaatat agattaatgt catatttgtg cttcatcata 2270761 tgaaaaacag actctctcgc cttccattta tcgggctgcg gccagagatc agtgcttttc 2270821 tgaataattt cacatctcag tttatggaaa tcagtctcgg atttttcttc ctttttcttg 2270881 aaataatatg aagtgcagta ggcaaaagcg gttgccagca tccaaaataa ataaaaggta 2270941 tggctaagta tttcttgaag tataagctga ggctccgggc ttttgatcat gatcataaca 2271001 cataataagc ctaggcagat aagtgaagcc catcgccatc tgcggcattg tgctgcataa 2271061 ttttcgaatt tttgttttcg ttttaccagc gcttggagca tctgtttggt cggcgcgtct 2271121 gtaaactgat ccagctgatt ccataaggat tccatacgct tcacaccttg tccattttca 2271181 ttgctacaat atatgaacgt aaaataaaaa taatacccta ttcatccatt aaagggatgt 2271241 ccaaaacttg tccggtgtaa acatcatttc cattcagatg attatatgct cgaatttttt 2271301 cttctcctgt ccggctttta taatacttca tggaaatgcg gtatagcgtt tctttctttt 2271361 ggacggtgtg cttgacaacg cgattcggca cattttgaac tggctcagct ggctgttctt 2271421 gctgttgtac tgttgattgg gaagaggaag cagccgcggc ggttgcttcc tccttatttg 2271481 gcgagtcttc tttttccgct acagcagtct gtttcttatc agcagctgtt tgctcttttg 2271541 gcttggaatc ttctggctct ttttttgact ccttctgcag tgcggtttct ttagtgtctg 2271601 cggtatcgtt tttatcctct gatttcggga caacctcata tttgctttgg ctgctgtcaa 2271661 taaaaacatc ttcataatcg tcatgattat ccgggtggct ctttagataa aataaggtga 2271721 ctaaaacgat aaccggcaca aatacaaata ttactgcgag tactgtgaat aatggcgttt 2271781 ttgttttgcc ttgctttttt ttctgttctc tttgattttt tacagattgt cttgtcggaa 2271841 ggctttctcc atcatcgaca taatcgtccg ccaatgcggc gttttgatct tcataaagat 2271901 tctgggcttt tcttctctct actctcgaca tgttcgtcat gtttatccct cctcacatgt 2271961 tcaaaacgaa tctgacaggc aaacacggca tcaatgataa aatgcgccgt catcggaaca 2272021 aataagttgc cggtccattc atacatcaga ccgagcaaaa agctgattgc tgtcaccata 2272081 ataaataaca gccattttga caaataccga aagtgcagag cggcaaatat aaggctggcc 2272141 gtccataaac cgatatgagt ctgcagcact cctctgaata acatttcttc cgcgaaagca 2272201 atcagaagcg ttaaaaatat aatatgaggg attgacctct tactgaatat ttttttattg 2272261 attccgccgt catcatataa atgagacgga aaccatttca ttactgccat atcggctaaa 2272321 ataacaataa cagctataga aacaccatac cagatgattc gcatatcgcg aatgtcccag 2272381 agctttaata cgtcccgtac atcctcaaaa aagaacagtc ctgctgcagc agcggcaaag 2272441 atgatgagta gctgcgtcaa atataactgc ttcagcatat catggtcagt catatgctga 2272501 atataatctt tttgctgttt cagttcagct cacctacagt ctgcaagctg aatatccggt 2272561 gcaattccga actccagctg tctaatggcg ccattttact ccgttcccct ttttgttcat 2272621 acaaggataa atcaaaaccg caatgtgaac agcacgggag gtttccgtca tcaggctcgt 2272681 atgattcatc aaagtaggtt aacagtgcct gccttaaaca gccgtcacgc tgaagcaaaa 2272741 atgatacacg gtgcattttt tccagcttca gctccatgcg atatgaaatt tctttcttca 2272801 tcagttcaac tgatgttttt ccctgcataa agagatgaat catcatacgg gcctgtgtct 2272861 ctccgacgcc atactgaagt aatacgtcac gcagccttct ctcatcccgc tcctccgtct 2272921 tctctagcac acggattacg tcggcgattt cttcagctgt gacactctcc atctggataa 2272981 tttgttcctg caattcaaaa tcccctggcg cccgcagcaa aatgctgaca ctcggctttc 2273041 cgtcgcgtcc cgctctgccg atttcctgca taaaagcttc tgccgtctgc gggagatgaa 2273101 aatgaatcac atatctgata tcaggtttat cgacacccat tccaaacgca ttcgtacaac 2273161 atatcacatc aagctggtta tgaataaact gctgctgaat taaaatcctg tcccctgact 2273221 ccaaaccgcc atggtaaaag tcggctctgc tgctcgtttt gcttttaatt tcacccgcta 2273281 attccttagc ccatttccgt gttggacaat aaacaattcc cggaccttgc aggttttcaa 2273341 ccagctgaat gaccctatct attttttcgg cagtatccgc cgcattttca accctcagtg 2273401 cgatgtttgg gcggttgact gagttgagat ggcgtacagc atgctgcagc tccagcaggt 2273461 tcatgacatc ttgcagcgtt tcctttgtag ccgtggcggt caatgccaga acgggtgggt 2273521 gtccaagttt ttttctcagc tgtccgagct ttgaataatc aggcctgaag tcgtgtcccc 2273581 attcagaaat acaatgcgct tcgtcaataa caaataggct aatcggaacg cttttcaatt 2273641 tttccaatac atatggagac tgtaaagctt caggagacaa gtacaaaaat ttatatcgat 2273701 gaatatgttc taaaacaaat tgtctttcct gcctgttaag catgctgttc aaagctgcag 2273761 cacgcttttc cccccgggct ttgagctgct gcacctgatc ctccattaaa gaaagcagtg 2273821 gagaaacgat taataccatg ccatcaagca tataaccagg cagctggtag caaagcgatt 2273881 tccctccccc agtcgggagc attgcaatgg tatccttccc gctgagtatg ctttcaataa 2273941 tgtcctgctg ccctttttta aaggaagtaa aaccaaaaaa ctgatataac gtttgctgta 2274001 atttagtcat attgctgcac ctgctttgtc aatgccagtc tgatttgaaa gtagctgaac 2274061 cgctgttcca gcccgtcgcg aatttgtttg attttattcg tccgcatccg tttggcaaac 2274121 tctgcgattt gaagctggtc ttctgctgat acatagtcat taatcataaa cgcaggctca 2274181 tggagagaaa tctcgacaat gtggtcttca atcgtcgctg ttttcagctt tctgatttca 2274241 gcaattcgct gtatcggaaa cccttgtttg accatctgcc atgttttcct cgtcgactct 2274301 gtcagggcat tatctaagtg cacatcagaa aggagatcct ttaacaaagc atcttcacac 2274361 tccggaagag aatgaataaa ataatgtacc gaagcccaaa acatgatata gacataccat 2274421 tcgtcttctt tcagcgtatc agcaagctgc ctgctcgtat aaccgatccg atggtgcgag 2274481 gttaaggagt agacaaaaat ttgcgctgct ttgttttcaa tctttttcaa atgcgcctca 2274541 agcatggcaa aaaggctttt tgccatctct atatgatccg tatgccggga caggtatttc 2274601 tttacccagt gaagtgtctt atgatccttt gtgacaggga tatactgcct gctcccttgc 2274661 tgtttatggg ataggacctg cacaagcagc gaaagccttt tccaaagcac gccggcagcc 2274721 tgctgataat gagcgccgtg acaatgaacg ggccaaggcc gctcgctaag ggcatgtctc 2274781 aaaactgctg cgccgctggc tgtcactttg tatgtatctg attcagacat tggcgcgaga 2274841 tatgaatgct tttcaagctt gtcaagcgac gcagaaatat cgcttctcga acattttgcc 2274901 gccattccaa agtattttgc agtctgaaat aagccggcat cttgaatggt ctgtgacgat 2274961 ctcttgcctt tgaataggtg aaaaacagcg cttcccgacc gttccccgtt tattttgcaa 2275021 agacaatcga gaaccataat atcgaagtaa tttaatgaca acctatccac ctacattctt 2275081 cctgacaaaa atcgttgatt tgctcttttt attttaacag atttcaaaca gaaatcgacg 2275141 tttaaagtca tcattaaggg ggatgttatg tagataaccc cttatgtgat aagcattctc 2275201 aatcattttt ctgttgaaat gtggcagcaa catcattaca ataagtaaga ggaataggtg 2275261 ttaaattgat taaatataaa gattgatcca tttgttccac caagaacaat ctgggaggtt 2275321 ttattcatgg caaagtacac aatcgtagac aaagatacat gtattgcatg cggcgcttgc 2275381 ggagctgctg caccagacat ttacgattac gatgatgaag gcatcgcgtt cgtaacgctt 2275441 gatgaaaaca aaggtgttgt cgaagttcct gaggtactgg aagaagatat gattgacgca 2275501 tttgaaggat gccctactga ttccatcaaa gtggcggatg agccatttga aggcgacccg 2275561 cttaaatttg aatagaagta actaaaaaaa gctcccgaac gggagctttt ttatttaatg 2275621 gatatgtgca cttcgctgct gctcaatcca tggcttaagc ttgataaaaa ttagtgagaa 2275681 tacaaccgta attacaatac cttttatcat gttaaacggc aggatacctg cgacgactgc 2275741 tgtttttagc gcgctgtcgg ataatgccgg tgaatgtaaa aaccacgtgt atgccggaag 2275801 aatcagaaca taatttaaaa tactcattaa aatggtcatc gctgcagttc ccaaaagcag 2275861 gctgacagcc aagccctttg ctgagttgag ttttttaaat aagaaagcag tcggtaatat 2275921 aaagagtgtt cctgcaataa aattcgcaac ttgccctaca ggaactccgg ccatgcttcc 2275981 ctgaatgata tactgaagaa cattttttat cgcttctacg gcaatacccg ccaaaggtcc 2276041 gtaaatcaga atggcaataa ttgcgggaac gtcgctaaaa tcgattttta aataatccgg 2276101 aagacccgga aacgggaaat ttaacagcat caaaacaaat gcaatgctgc tcagcatgct 2276161 gaccacaact aattttttta ctttcacttc attctctcct tttcgatcac atcttactcg 2276221 aaaacggaaa ggttcttttc cagccaataa aaaaaccgct tcatatataa aagcggggtt 2276281 tcgaaaatta ggctaggcaa agaaacgttt gaaaaattca atttcaaaac gcttatgaac 2276341 ctccatcttc tcccatccag actgtactgt cggctccgga atctcaccga atcctgctgt 2276401 aaagacagct cgcgggctta gagccattgg ctcatcaccg ccggtaggga atttcaccct 2276461 gccccgaaga ttgatcatat gaaatttaat tacattataa acgataactg gttggctgta 2276521 tagagaattg cttcaaatta aatatattac ctgcaagctg tcagatcatt gatttattag 2276581 gctttacttt tatcctttac tgcgtcaata cacgttgaca ctcttttgag aatatgttaa 2276641 attatcagat atttagtttg tcaatttagg aggaaatcta acgatgtttc gagtattggt 2276701 ctcagacaaa atgagcaacg acggtttaca gccacttatt gaatcagact ttattgaaat 2276761 cgttcaaaaa aacgtagcag atgcagaaga tgaattacat acttttgatg ctcttttggt 2276821 gcgaagcgcg acaaaagtaa cagaagacct tttcaacaaa atgacttctt taaaaattgt 2276881 cggaagagcc ggtgtcggtg tcgataatat cgatattgat gaggctacga aacacggggt 2276941 aatcgtgatc aatgctccga acggcaacac catttcgaca gctgagcata catttgcaat 2277001 gatctcttct ttaatgagac acattccgca ggctaatatc tcagtgaaat ccagagagtg 2277061 gaaccgcaca gcttatgtcg gttcagagct ttatggaaaa acgcttggta ttgtaggatt 2277121 aggccgaatc ggaagtgaaa ttgcacagcg tgcgagagcg ttcggtatga ctgtgcacgt 2277181 ttttgatcct ttcttaacgg aagaaagagc gaaaaaaatc ggcgtaaaca gccgtacatt 2277241 tgaagaagtg cttgaaagtg cggatatcat taccgttcac acgcctttaa caaaagaaac 2277301 aaaaggctta ttgaataaag aaacgattgc aaaaacgaaa aaaggcgttc gcttaattaa 2277361 ctgtgcgcga ggcggaatta tcgatgaagc agcacttctc gaagctttgg aaaacgggca 2277421 tgttgcggga gcagcgcttg acgttttcga agtcgaaccg ccagttgaca acaaacttgt 2277481 tgatcatcca ttagtcattg ccactcctca cttgggagca tcaacgaaag aagcacagct 2277541 caatgtcgcc gcccaagtgt cagaagaagt tctgcagttc gcaaaaggcc tgcctgtcat 2277601 gtcagctatc aacctgcctg ccatgacaaa agatgaattt gctaaaatta agccttacca 2277661 tcaaattgca ggaaaaattg gcagccttgt atcacagtgc atgaaagaac cagtacagga 2277721 tgttgccatt caatatgaag gcacaattgc taaacttgaa acatcgttca ttacaaaagc 2277781 ccttctgtca ggctttttaa aaccgcgcgt agactctact gttaatgagg tcaatgccgg 2277841 gggtgtcgca aaagaacgcg gcattagctt cagtgaaaaa atttcctctt ctgaatctgg 2277901 atacgataac tgcatcagcg taaaagtgac aggagaccgc agcaccttta ctgtaacggc 2277961 tacgtatatt cctcatttcg gagaacgaat tgtcgagatc aatggattta atattgattt 2278021 ttatccgact ggtcacttgg tgtatatcca gcatcaagat acaacaggtg tcatcggccg 2278081 agtaggacgt attctcggag ataatgatat taacattgca actatgcagg ttggccgtaa 2278141 ggaaaaaggc ggagaagcca tcatgatgct ttcctttgac agacatctgg aagataaaat 2278201 tgtgaaagaa ctaacaaatg tccctgatat tgtgtctgtg aagctcattg atctgccata 2278261 attaaaaaaa ctcaagctat atagcttgag tttttttatt gttctatccc cgtgtgtttt 2278321 tatgcaaaat atctaagaca ctccttagct cagaaacagg aatttggcct ggtgcggacg 2278381 cctcttctcc agctccaaaa gtacaagccg atccaaaaac ctcaccgctc agcctgctga 2278441 tgagccctgt tgcagccatt gacattgtaa taatggggcg gtctgcatat attgttttca 2278501 ttgtatacgt cgcatcaagc agtgttagga gatctccagt atcattcggc atgacagcca 2278561 tttttggaat atgcgcgcct aagtcctgca tttttcgaag tctggaaata atttcatctt 2278621 ttacaggtgt tttttcaaag tcgtgatttg acatcaccac atagacgttg ttttcttccg 2278681 ccagcgatac taacgctttt acatttgcat ctcctgaaaa taattcgatg tctatcagat 2278741 cgatgtcttt tgtttggatt gccgattcca gcaaagcaag ataggagctt tcgtccatct 2278801 ccatgctccc gccctctttg tgggttctga atgtaaatag aaatagcttg tcttctaaag 2278861 atttacgaag cttagaaatg agctttgtga ccgcttctct gtcattcgct ttttcaaata 2278921 cgtcgactct ccattcaaca atgtccggat tcagtaattt tactgcctct gcttcattca 2278981 gaatttgttt ttccgtcttt cccatcagcg gaatgatgat tttcggcatc ccttccccga 2279041 tggaaactcc tttaatcgtt aacacgttca ctcgtctcaa atcctttcaa tctttacctt 2279101 gttttattat acacgtacaa cttttttttg aaaatttcta ttatatgaat agcaactaaa 2279161 aaagagcctt aaagggctct ttttagttta aggaaatcgg atttggagca gctggcaccg 2279221 gaattgcatc tgatatgtca tatttgccga tttttttcgt tctggtttcc gtaaaggtca 2279281 cttctgtgaa gccaaactct tttgcagtca aaagtagtcc ctcaatcatt aaaataccgg 2279341 caatagaatc atcaacttct gactcctttg aaaagcggat atataagtgt ttctgtttct 2279401 tcgttacaga ttggacagca cccgcttgaa taagaggtgt cgtatcttct tggctgctcg 2279461 attccatttc cttaatcgct tcttttactg tatcaaaaga atgatttgac ggaacgagaa 2279521 agtcttgtcc ttgtttattt tggtacaagt agtaggatcg ttttgactgt ttgggaatcg 2279581 aaatttccgt aaaagtgcca tatgagccaa tccgaacccc agtctcattt tgatccgata 2279641 aaaatttgac tttttcataa ggactccatt ttaaggattc tttaagcaat ttttttaaca 2279701 gtgtatcatc ttttatagaa aatgccgtag ctggctgatg gactcgtata cttaattcct 2279761 tctgctttgg tttttccttt atttctactt catctatgaa ggttggaatt gtaatggcat 2279821 gatcaaggat gcccaattca ctactttcaa acagcatatc ctggatcgtt tggtctgcat 2279881 ttgttttttg aatgctgacg ggtatgattg cagatgtatc ggcatcagca accgctacag 2279941 tgatgtaatt gtcttgttcc ttttcaggaa cgacaaacga tgtctgatcc aaggacgatg 2280001 cagcttttgg gctgtcttct gtctcagttt tcgttactgc gttctcttgg gacgcttctt 2280061 tttgttgagg ctgtgcctga tcaaagaaat gaggagaaat aatgaaggcg atataaaccg 2280121 caattgcagc ggcacacgcg gggccaatcc acctgacagc gggcttattt ttacgctttg 2280181 ccatcgtcag ccgcttgtaa atatcctgag gcgaacgatg gtctttaact gccggaagtt 2280241 gacttaacaa ctcctttatc tgttcttcgt tccattctga cttcatcatc cattagctcc 2280301 tccctcaaaa gctccatatg tttccgaagt actttgagcc ctctgtgttg ggtcgttttt 2280361 actttgcttt ccgagaagcg cagagccttg gctgtttcct gtattgaata tccctgaata 2280421 aaccgcaaga taatcacagc tctttgatcg attgtacatt gatcaagcgc agcataaatt 2280481 tcccggacat tttcatgttg aaccgcaagt tcgtccggca gcaattgctg atccctgaca 2280541 tcctgtgtat cccagtcaaa tgtaccgagt atacgctgtc tgattgtttg ctgtttacgg 2280601 aaccagtcta tcgcaacatg gcgtgcgata gacaaaagcc atgttttttc actgcttctt 2280661 ccttcaaacg tatgataaga atttaatacc cggatataaa cctcttgaag aaggtcttct 2280721 gtctggtttt tatcctttac catataaaat aaaaattggt acaaatcttg atgatatgta 2280781 tcatataata attgaaaggt ttcttccatt tgaaacccct ccgttcactt ttttgtcgta 2280841 tgaatagctt gaaaagttac attacaacta tattacgagt aactggaatt tggaagggaa 2280901 tttatattaa catatcctta aattttatta atgttggcta ttaaaaaaac acccgctcag 2280961 tcagcgggtg tttcttatgg aacaagattc ttcggcaaat tcagactcga ttttaccgtt 2281021 ttgtcggaat ataaaaagaa aatgttgttc ctttatctat tcggctgtgc acagtaattg 2281081 atccgttgtg ggcttccacg atatttttaa cgatagccag ccctaacccg gttcctgctc 2281141 tgccccttgt ccgcgcttta tctgccttat aaaaccgctc aaagataaat ggcagatctt 2281201 cttccggtat gccagacccg gagtctttga tatcaatttt caatccatcc ttcacagaat 2281261 ggactgaaat ggagacactg ccgccggctg aagtatgccg cagcgcgtta tcaatcaaat 2281321 tggtaaatac ctgctccatc ttgtcttcat caaacataaa ttcctcttct gtgagagaaa 2281381 tgtcatgatc taaagcaata tttttttctt tcgcaacacc ggaaaacttc cgaatgatct 2281441 tttctaaaaa ctcattcaca ttgatttttt cataatgtaa gcctgtatgg cctgattcca 2281501 ttcgggctaa atcaagcaaa tcattaacta aacggcccat tcggagcgat tcgtcataaa 2281561 tgatttgggc aatttctttc cggtcttctt cagagcttgc aatgtcatcg acaattgctt 2281621 cactgtatcc ctgaagcatg gagatcggtg ttctcagctc atgactgaca tttgcgataa 2281681 agtcctcccg cagcttatca aggcggcgtt cttctgtcat gtcacgcagt acggcaaccg 2281741 ctcctctgac gtgcgattcc gcataaagcg gcgacatcaa aagcacccat gatctgcctt 2281801 gaagcgtcat ctcaatcatt tgttcttttt cagtgctgac agcgttttga aacagctctt 2281861 ttgcttcagg cggaagattg tcgccttctt tgatattcat gttctgttca taataccaag 2281921 cctgaagaaa acgttcagcc ggcgggttgg tcacaagaat cgtaccgtca atattaatgg 2281981 taataacccc gtcagccata ctgctcaaaa tgttagaaag ctgctctttt tcttgattga 2282041 gcgcattgat atgaaagtta agctgccggc ccatttgatt aaaagcggtc gccagttcac 2282101 cgatttcatc ctgagttaaa atcgggattt ttgtatcgaa cttgcccttc gccaaatcct 2282161 gcgcgccttc tctcattttt cggagagggt acgtgaccct gcttgataaa aagaatgcga 2282221 aaaatgtggt cagcacaatc gcaattccag cggcaagaaa aatatagcgg gtcgtatgtt 2282281 ttgttgtatc tttaacggca agcaaagact gggataaaaa gaccatgcct ttctttccgt 2282341 ctttttcata cgggacacct acaatcaggc gttcattatc cgtgtctgta tcgctcagtc 2282401 ccgtccgttt gcttactttt ttatggtctt tgagagcttt atttaagtct ttgtcatgct 2282461 gtatttgctc aaccgtaata gacgacaggc gatttttatc attcggagaa taccagtggt 2282521 tcttctcatc ctggatgatg gcaatgcttg ttaagttatc agcgagttcc caagtgattg 2282581 accttgccag tgcctggtcc tcgtgatttt ctaggatgac agcaacttta ttcgcaagct 2282641 gtgttaaatc attctcagct tcttccacat ggtagttttc aataaactcc agcaaaagaa 2282701 ccgttaaaat gaacaatacg atcaagacga gtgaaaggat cgtaaaccac agcttgccta 2282761 ctacgctttt ccaaaatttc attcagcgcc gacctcaaat ttataaccta caccccatac 2282821 ggtgacaatt tttttcgcag cttccggaga taccttgttc agcttctctc tcaagcgttt 2282881 gacgtgagtg tccactgtcc gtaaatcacc aaaaaactca tattgccaca cttctttcag 2282941 aagcttttcc cgatcataca ccttgtcagg cgttttcgct aagaaatata gaagctcata 2283001 ctcttttggc gtcaggctca cttctgttcc atcagctgtt acgcggtgag catcatggtc 2283061 tattgacaga tgtgaaaaca cgagcacatt tttcgtcggt gtattggcat tgaaataaga 2283121 ggtttgggat gctcttctca aaagggcctt tacacgcagc acgacttctc tcgggctgaa 2283181 cggcttaaca atataatcat ctgttcccgc ttcaaacccc tgcacccggt ttgcttcttc 2283241 tccttttgcg gtcagcataa taatgggtgt cgcttttttt tcacgaattt gccggcacac 2283301 ttcaattcca tcagtccccg gcatcatcag atcaagcaaa attaagtcat aattggcttc 2283361 aagccctttg gcaatggctt catcaccatt ttcagcttca tctatagcat aattttcacg 2283421 ttcaagatac attcttaaaa ggcggcgaat tctggcttcg tcatcaacta ctaatatttt 2283481 tgtttcgttc gtttggtcca tgttttcccc ctgctttcct tctgttactt tcattttatc 2283541 aaatcgtgag aaagtttgag aactgtgtcg ctttcaaagg actatgcata agaatgaagt 2283601 ccggcaagca caagatttac gaatattaaa ttaaacataa taatagcaaa accgattacg 2283661 gccagccatg ctgacttctc accgtgccag cctcttgaca gtcttaaatg caagtaagcg 2283721 gcatagaaca aaaatgtgat cagcgcccat acttccttag ggtcccagcc ccaaaatctg 2283781 gtccacgcga gctgagccca aatcattgca aagatcagcg cgccgagtgt aaagatcgga 2283841 aatccgattg atacggccct gtacccaacc tcatccacca gatcaagatt gacgtttttc 2283901 accagcggat gtaatagagc gctgattctt tttctgatga tcagacggag agccccatac 2283961 aacacaagac ctgctccaaa tgaccaaatg acagtgttca cttttctgcc tgagaaaagc 2284021 gcgggaagat caacaagcgg ttccattctt ccttcggtca aaagctctcc ctgatgcgga 2284081 ccgacaagcg cgggcatttc gtacaccatc acgctttttt ctttactttt gtccacccag 2284141 ttaaactccg cttcatagcc tgcaagacga aatgccgatg tgattgcaat aaaggcgacg 2284201 gttgtgacca ggataaacat aatcgcttca agccagaagg tctttttgct tggctttgtc 2284261 tggtctacat gcttcaaaag aaagatgaca ccagcgacaa agctgatggc aagtatagct 2284321 tgcccaagcg cggccgttgt tacgtgaata tacagccagt tactttggag cgaaggaatt 2284381 aaaggcgaga tatctgtcgg aaacatgctg gcgtaggcaa tcagcaataa agcaattgac 2284441 agcgtaaaca ggcctaatga aggcaatcta tagagaaaat aaagaatgat aaacgccaaa 2284501 acaagcatca tgccaaaagc ggtggtgaat tcaaacatat tgctgacagg cgcatggccg 2284561 cttgcagccc accttgtgat gaaatatcct aggtggcaga aaaaaccgac aatagaaagg 2284621 gtgattccaa tgttggccca tcggtttggc ctgccctttt tatctttatt cccgcgtatg 2284681 gccccgccga agattgggac agcgattaaa tacacaagaa aggccgcata aagaaaattt 2284741 ccgctcagct ctgccatgac atcactccct tttcgcctat ttctgtgttt tgattaattc 2284801 tttttggtcc accggttcag tcagtccgga atcagccaat ataaatgcta aatccttctt 2284861 caggccaaac cagtttttat tggtatgccc tgctaccata actgcaccgt cctgtgagtg 2284921 cagccaaatt cttcgatgct gccagtacat accttgaatg acaccgatca taaaaatggc 2284981 tccgccgaca gcaagcaccc agagtgtcag atcctttctg actgtaagtc cagtaatgtt 2285041 tttcgtttcg acatggtcaa atttcagctt gtatttatta ttgcctgatc cttcgatggt 2285101 ttcttggatg gcgacaaagc tcttttcgcc tttcggtttg tccggcgtta tgatattaaa 2285161 gacaaaagcc ggattgttag ggatctttgt ttttgtgctc ggctctccgt cctgattaaa 2285221 atagaagtca ggcaggtagc tggcgatttc caccttgtaa ccgttaccaa gatcatagac 2285281 tgaatctgga tccagaaggt tgatcttcag gctcccaaag gatttttttg tttttttatc 2285341 aatcagctgg aacaccattt ggtcaagctg attctctttg taatccacct ggtaaacgga 2285401 aaaagaatca aaacgcagcg gctgattgac acggatgtct tcttctgtta ctttttccag 2285461 cttcggcttc tcgccataaa caatttttcc ttctctcttg tagagtacgg catcagtttg 2285521 aaagttcttt gccactctac cgtccccgac tctgtcaatg gcatctgcaa ataccttttt 2285581 ttccgttttg ctgttatagg tctctacgct gaattgattg tttttcaaat aatattttcc 2285641 gtctgtaccc ggaattgctg cggtttcgcc ttctctgacc caaagcgtct catcgacgta 2285701 catgccaggc acaaatctca gcatcgcacc aatcagaaag atgatcaatc caatgtggtt 2285761 gacatacggg ccccagcggg aaaagcgtcc tttttcagca agaatgctgc cctctttttc 2285821 tctgattcta taatgttttt tctttaatag agtaactatc ttttctttcg attccccgtt 2285881 cagtacagta actgtttcac tgaacaagcg ctgccttctt aaaaaggccg ggctccttct 2285941 gacaccttgg ttttttaacg ctctatacaa cggaatgacc cgatcaaggc tgcaaatcac 2286001 gagtgaaatg ccgatcgagg caatgagcag caaataccac caagaaccat ataaatgatg 2286061 aaacccgagc aaataataaa gctggccaaa cgtgccgtac tgctccttgt aataagtatc 2286121 agcctgtgcg cccggaggca gataggcttc ctggggaaaa atggtgccga acgctgatgc 2286181 ggcaagggtt atgacgataa gccatattcc caccttaacc gaggaaaaga aattccaaat 2286241 tttgtcgatg atcgttttgt tataggtttg cgaacgtctt gcgcttccgt catatctcat 2286301 atcagcgagc ggaggttgag tttcctgaag agctcttccg cacgattcgc ataaaacggt 2286361 tccgaccggg tttatatgtc cgcattcaca tttgacttgc ttcatcccga agtctctccg 2286421 ggttttatga gattcatata atcgtgtatc atgctttctg tcatagtgcc ggtcaccacc 2286481 ttgacaactt ttccttccgg attgatcaaa aaggttgtcg gaagcggaga tacgtcatag 2286541 gcatcaagca cttggcgatc tgtatccaga acaaccggga aattgactcc gtaggatttc 2286601 ataaaattat gtactgctat ctttgactcc ccaacattta cagcgacaat ttcaacacct 2286661 tggcttttaa aatgcttata ttggtttgcc atataaggaa actctttttt gcacggttca 2286721 caccatgtac cccagaaatt caaaaaaaca cctttccctt ttaagtcact gagctcgata 2286781 cgtttcccat tcgtatcctc taggacaaaa ttcggtgcgt cggacccttc ggatatactc 2286841 tctttgccgg caaatacagc gttgtaaatg gtatagccga gtgcgcagat taaaacgaga 2286901 aggatgccgg tccgaatgaa taaacgcctt tttttcttca ttgtccactg cccccttccc 2286961 cctattgcag atccattcaa ttatatcatt gcacgttcat ttcacatttc ttactttttg 2287021 aaggttatgt gaaatttaga aagcgttttt accgtgatcc gccagtgctc tgagcctttt 2287081 tacttcgtga ggcgtaagct ctctggcatc gcccgtgtgc aggcctcgca ggtttaaaaa 2287141 cgcgtattcc tcacgcttca gcttgattac ctcatgtccg atcgcttcaa acatgcggcg 2287201 cacttgtctg ttgcgtccct catggatcgt cagctgaata atgcttgtct gctttttctt 2287261 atccaaagac agcagcttcg ctttagcagg cgctgttttg ccttcctcca gcctaattcc 2287321 gcgctccagc tttctgagca gctctttagg cgggattcct ttcaccttcg ccacgtatgt 2287381 tttgtctatt tcatacttag gatgcattag cttattggcg aattcgccgt cattggttaa 2287441 aagcaaaaga ccgctcgtat catagtccag acgcccaatc ggataaatgc gctgcggaat 2287501 atttttaaaa aagtccgtca ccactttgcg tcctttatca tcttgcgctg cggaaataac 2287561 gcctcttggt ttatataaga gaaagtaaac cggctcttcg cgttcaacct ttaacccgtt 2287621 tacctcaatc tgatcagaac cggtgacctt aacacctagc tctgttacta ctttgccatt 2287681 cacctttact tttccttctt taatcagctc ttctgccttt ctgcgcgacg caactccggc 2287741 atgagcaatc actttttgca gtctttccat gtctttcacc tcaagtatta tcttactttt 2287801 ttcaacctta acaaacaagc tttttcaaat tcctatgcca aatctaaaaa aaacgccgtt 2287861 ttcaggcgct cccaaataat aacgtaacga tgatgataga tgcaactacg ccgattaaat 2287921 ctgcaagaag tcccaccttt aatgcatcac ccattttttt aatgccgact gctccgaaat 2287981 acacagtcag tacgtaaagc gttgtatctg tagatccctg catgacggaa gccagcctgc 2288041 cgataaagga atcgggcccg tatactgcaa ttaaatcggt cgtcattcca agtgcggccg 2288101 taccggagat cgggcggatc agagcaagcg gcactacttc agcagggatg ccgatagcgg 2288161 agaaagccgg ttttaaaaga tccattataa aatcaagcgc gcctgatgat ctgaaaacag 2288221 ttatagcgac aagcattccg actaaatagg ggataatgga aaaggcaatt tctatcccct 2288281 ctttcccgcc ttcgacaaac gattcatatg tcggaacctt tttgatcgtt ccataaagaa 2288341 gaattccggc aataatgatt ggaatcatgg ctaaagacag ccagttgatg atttccatcc 2288401 gctcaccttc ccttcttttt gcggcggtaa taaaaatacc gatcaatgat aatggcaccg 2288461 attccggaaa taagcgttgc caaaatgctt ggcccgacga tatctgtcgg cgttttggag 2288521 gaataagcca ttcggacagc gatcaccgtt gtcgggatga gtgtgatgca ggacgtatta 2288581 acagctaaaa aagtaatcat cgaccggctt gcttccgatc ggtttccgtt cagctttttc 2288641 atttgttcca ttgctttaat gccaagcgga gttgctgcat ttccgaggcc gaagaaattc 2288701 gccataagat tagataaaat atagcccatc gccgggtgat ccggcggtat atcagggaac 2288761 agtttagata taaaaggtct gcacatccgg ctgaaaatat ccaaaagccc tgactgctcg 2288821 gcgattttca ttaagccaag ccagaaaaca agcacgctca tcaatccaaa tgagatcgta 2288881 atcgcttctt tcgcaccctt aaacacggct tcatttacat cttgcagagt tccgttgcac 2288941 atcgcaaaaa cgagtccgat cacggttaaa ctgacccaaa ttatattgac cattttgctc 2289001 cgcctgccgc attcagaaag attgatttaa acgtttcaaa aaattgtttc ttcggttttt 2289061 gatgccgctc attttcataa tagatcggca cttttgcgat ggttgcatcg ttgaacatga 2289121 tctccatgtg ccctacgatg tcagggattt tcgaggcatc tttttcccat gcttttttcg 2289181 gcttgagcag tgtggtatta atttttacat tttctttttc ctcttcggtc agcaaatagg 2289241 tgatatcacg tttgataaaa gccttcgatt cataaaatgt gcctttcagc tttggaatat 2289301 cccctttttt tgcaattaaa taggtttgat aatgctcaaa cacatagtta aacatcttca 2289361 tatggtcatc ccaatcatta gggtcattaa tggtgacggc tatcaggtca atgccgtcct 2289421 ttgaagccgt agagaccagt gtccgttttg caagttttgt atagcctgtt tttcctcctg 2289481 tgctgtacgg ataaagcatg gtcagcagtt tgtttttgtt tttccatacg ctttccatcg 2289541 tttccgcttt gtatattttt gtgcctgaaa tcttttgata gtctttcagc ttcatagcat 2289601 acttagttaa aatggccatg tcataggctg ttgaataatg attttcatgg tcgtccaatc 2289661 cgtgcgggtt ttgaaaacgg gtgtttttca taccaagctg ctcggctttt tgattcatca 2289721 tataaacaaa cccatcgagg ctcccaccga catgctcagc aatcgcgaca gcggcatcgt 2289781 ttcctgatct tagcatcagg ccatacacaa gatctttcag cttcactttt tgaccttctg 2289841 ttaaataaat ggcggagcct tctgttctga cagcatttgc cgaaaccgtc actgtttgat 2289901 ccattttgcc ggattcgatg gcgaggacgg cggtcataat ttttgtgatg ctcgcgatcc 2289961 gccttttttg atgctcatcc ttggcatata acactctgcc tgacgcaccg tcaataatga 2290021 tcgcgctttt tgcactgaca tctatagcag catgtgctgt attcacattt acggttgcaa 2290081 taagaaaaga aatcatgatc acgaatactg cttttttgaa aatgcgcatg tttgctcacg 2290141 tccttgtggt ggtttgtaca agtttatgcg catgtccatc agttatgaat aacaattata 2290201 tttctggaag caaacataaa aaaactctcc ctgaaaaagg gagagtaaac gttatctgat 2290261 tggcgccatg cttgatccgg acgcttcgta atgagccagc tcttccctca tcttcagaaa 2290321 ggccgcgctc aacggcaata ataattgctc aagcgacgca ggaacagcat gataaaactc 2290381 aattgcgctg accccggtat aagacgcccg gctattttca caccacgtgt cttttttcgg 2290441 cataaagaac tcttcaatgc attggtgata cacattataa agtgtttttt ccgctctggc 2290501 ttcctgaaaa ggctcctgca tcaggagacg acggcacgct tctgcgcctc cttcacaaaa 2290561 tactgccatt cttctcagag tgctaagcac atcacagcag tatccttttt caataggcaa 2290621 ttcagcctgt aaggactcaa gcgtcgtttg atttaggtaa tcgttcacgg tattgacaac 2290681 cattgataag aattcgcctg ttttttgagt ctgcgctcgc acaatcgaat gtcccatttc 2290741 gtttggtatc ttcccctcat gtatttgtct ctcacatttt gcttctttca tgatagcttc 2290801 ttccttatat cttatgatga tgaaaaagcg cgattcatta aacttctatt ttatatcttc 2290861 gaaggtttgg ttaaagtttt caaaaaataa atctgcttct tcttgaagaa cgtcttcttc 2290921 cgcattttca ggcagcggcg gaagctcgtc cagcgttttc agaccgaatt gttcaagaaa 2290981 agtcggcgta gtaccgtata aaatggcccg ccccggacca tcggcacgcc ctacttcaca 2291041 caatagcgcc ttcgcgacaa gactgtgtaa aatccgctct gattttactc ctctgatttc 2291101 ttcaatttct gctctcgtaa ttggctgttt gtatgaaaca atggccagta cttctaaaga 2291161 tgcttgagaa aggccctttg acggcacttc aatcagtttt ttcaagtaag gcgcaaagtc 2291221 ttttttggta gagagcatgt acgtatctgc atactcaata agttcaatcc ctcgtgtatc 2291281 tccgcggtat tcgtccgcca catccgccat gatcgtgttc agttcaggct cttcgatttc 2291341 aagcactgtt aacagctgct tttttgtaag cccttcatcg cctgccgcat aaagaagggc 2291401 ttccacaata gctttccaat tcacgatatc aagccccatg aatggattca ctccccgtaa 2291461 tgtaaatatc tgaaaaattg tgctcctgtt caatgaggac cagctgattt ttcatcagct 2291521 caagaacagc tagaaaggtc actactaaat gttctttttg ctcatatgga aacagatcca 2291581 taaagttaat tctcgttcct ctagatttca agctgtgcac gatttcgttc attctggctt 2291641 cgattggtat gtcctgtctt gtaattgttg tttccatcgg cctgtttatt tttttgcgtt 2291701 tcagcacttt ttgaaaagct ccgatcatat catagaccgt gacagagagc ttttgctcag 2291761 actgttttac ttcttttgca tattcactca aatcactcgg cggtttcgtg aacgattttt 2291821 gtctttcttc ttcccgttct tttaaatcct tcgccgcatc tttatatttt cggtactcaa 2291881 tcagcttttc aatcagttcc tcccgcggat cttcttcttc aagtaattca tcttcaaaaa 2291941 gctcctcctc ttgcttcggg agcagcattc tgcttttaat gctgagcagc gtggcagcca 2292001 taaccaaata ctcgctggca atgtcgagct caagcacgcg catcgtatgt acatataata 2292061 aatattgttc agtgatcttc gccacaggta tatcatatat gtcaatttca agacgattga 2292121 ttaaatgaag cagcaggtcc aatgggccct caaacgtatc aattttcact tgatattctt 2292181 ccatcatctc accattttca agtatcactc tcattgccgg aaaaactggc taccctatag 2292241 tataagccac caaaaagctc tcgtccaata ctatttcata tcctgttttg aaggagtttg 2292301 tacagaatat tcaaaacaca agaggtgttt gctcggagcg cagaagcggg agaaaaagcc 2292361 tttgcttctg gttttccttt ctaagaagca ctagaggccg ggcgttcttt tttcctttta 2292421 tcccttctat ggtacactaa aagcacatta aaggaggaag caccttgtat ccgaaagctt 2292481 atatagatta tctcgttgag tttcatgcga cacgggatta ttttgaatgc catgaaatat 2292541 tagaagaata ttggaaggaa gatccgccaa agaaacgaaa acgctattgg gtgggcttta 2292601 ttcagcttgc agtggcttta tatcatcaca gaaggcagaa tacagccggg gcaaaaagac 2292661 tgatggcgaa cagcatccgg attcttcaag cagaacaccg ggcagtcgaa gacttagggc 2292721 ttgatcatgg ccgtttgctc gaacttatgc aatcggttta cgaacaaatc gaaaccgtct 2292781 ctgcctataa aagcattata ctgccaatca aagatgagaa actggaggaa gcatgcagga 2292841 tcgaatgcag gaaaaaaaag tatacatggg ggcagcccag tgcactcagc aacatatttc 2292901 ttatcgacaa acaccgtttg cgggatcgga ctgacgtcat ccgtgaacgt gaaaaagaaa 2292961 tagaacgcag aaaaaaaagc agagactgat cacagcctct gcttaattat tgtatgaaat 2293021 gtcttgatcc tgctgacctt gacaacgttc gaaaaagctc tgcgttaatt catttggaac 2293081 cagtacttgc gttttgaata aatgctttaa agcatccatc atctgttttc cgattccttg 2293141 atggcgatga gaaggattca cactgatatg ccggatctca acctcagaat cctttttttc 2293201 gactccgatt gctccgacga tatcctcgtc ctctttccaa agaaagagct ggcggtctgt 2293261 atccgtttcg tagtccttaa ttgtctgctg aagctgctta aggtcttttt cattcggcat 2293321 aaacgaaaga agccccatcg caatcttttc aaacgatttt ttataacgaa ttaacataaa 2293381 aacccctcta tatccaaaat gtccagtctg ctattaacgg atacgaatag gtgatccgtt 2293441 ttctcacatt atatcatttt cgccatattt ttaaactgtt ttcagcaaat tattcaaatg 2293501 agcggtttaa atttgccatt tcaatggcag aaacagcaca atctacacct ttgttgcccg 2293561 cttttgtgcc ggcacgctcg atagcctgtt cgatgttttc agttgttaca attccaaaga 2293621 tgacaggtac accagtagtg tttgctgctt gcgcgatgcc ttttgcagct tcattgcaga 2293681 cataatcgta atgtgtcgtt gcgcctctga tgacagtgcc caatgtgata atagcatcat 2293741 atttttttgt ttccgccatt tttttcgcag caaacggtat ttcaaatgcg cctggaaccc 2293801 aagccacatc aatgtcattt gtgtctacgc catgtctgag cagcgcatct tctgctccgc 2293861 tcagcagctt gctcgtaata aaatcattaa atcttcctac tacgattccg attttaagac 2293921 ctgtaccaac taaatttcct tgtatgatat tcatatgatt cccatccttt tttgtgatat 2293981 ttgtgattag aaatgaagta aatgacctag cttgttcatt ttggtttgca aatatttttt 2294041 attgtgttct ttcgcctcca tttgaagcgg cactctttct gaaatactga gtccgtagcc 2294101 ttcaaggcct gcgatttttc gcggattatt cgtcaaaagc ttcatattcc ggacaccgag 2294161 gtcgcgtaaa atttgtgctc cgatgccata gttgcgaaga tccggcaaga atccaagcgc 2294221 ctcattggct tctacggtgt catagccttg ttcctgaagc ttataagctt ttaatttatt 2294281 gattaaaccg atgcctcgtc cttcttggcg caagtacagg agcactccac ggccttctgc 2294341 ggcaatttgg ttcagcgcgg cgtgcagctg cggtccgcaa tcacagcgat gagagccaaa 2294401 cacgtcacct gtgagacatt ctgaatgcac ccggaccaat accggttctt ctccgaacgg 2294461 cacatctccc atcacaaatg cgacatgctc ttttccatct acctcatttg tgtatccata 2294521 aaccttaaat gtcccaaaat cagtaggcag cgtaatgtca acttcacgct cgacaagtgt 2294581 tgtcagattg taacggtatt gaatcaaatc cttaatggtg atcattttta attgatgctt 2294641 tttcgcaatt tcaatgagct caggcactct cgccatcgtt ccgtcttcat tcataatttc 2294701 acaaatgacg ccggctcctg gagatccgca agcttcagca agatcaacag cagcttctgt 2294761 atggcccgct cttttcagga cacctccttt tttcgcaatc agtggaaaaa tgtgccccgg 2294821 acgctgaaaa tcagatggca cggatttgct gtccagcaat gcttgaacgg taaaagatct 2294881 ttcttgagcg ctgatacctg tcttcgtttc acgatggtct atgcttacgg taaatgcagt 2294941 gtggtgagag tctgtattat gctcaaccat agggtgaaga tcaagcctgt ctgcgatttc 2295001 ctcactgagc ggcgtgcaga tcagtcctct cccatgtgtc gccataaagt taatgacttc 2295061 cggcgttgca tgctcggcaa gagccacaaa gtctccttca ttttctctgt cttcatcatc 2295121 tacaacgatg atgacttcgc ctttttttaa agcgtccagt gcttcttcta tcggatgaaa 2295181 catgcaaatc ttcctctcta aaagccgttt tcgcttaaga aggcttttgt aatggtttgt 2295241 tgggtcttat tttcattggc tttatgcaaa aatcgataca tatattttcc gatcatatcg 2295301 cattcgatat tcactttaga gccgatcgtt ttttctgaaa agatcgtttc gctgatcgta 2295361 tgcggtatta aggagatcgt cactgtgtct tctgtcaggc cgaatatggt taagctcacg 2295421 ccatccacag taattgatcc ctttaaaacc aatgtttttg ttaatgacgg gtccattttt 2295481 aaatcatagt aaactgcgtt gcttttctct tcaattcgtg tgatttccgc agttccgtcg 2295541 acatggcctg agacgaaatg gcctccgaaa cggccgtttg ccgccatcgc tctttccaga 2295601 tttactttgc ttccttttgt taaatcattc agtgacgtag ctttgactgt ttcaggcata 2295661 acatccactg tgaattgatt ttttgtaaaa tcagtgacag tcagacaaat gccgttcact 2295721 gcaatgctgt cgccaagatg aacatcctct aaaatctttg agcatttaat agttaaggcc 2295781 attgcatgcc ctgctttttt catggattcg attgtgcctg tttcttcgat aattcctgta 2295841 aacatggtca ccatcctatt cctttgtcgg ttttgccgtc agtttgatat cacggccgat 2295901 ttgggttata tcagtgaatt gtaataaggg gacatctttc attgattgaa aaccttcacc 2295961 ggagattaag ctgggagcat gcgttcctcc gattagttta ggggcaaaat agaagatgat 2296021 ttcttgaaaa cagccttctt tgacaaagct tccgtgaaca gctgaaccgc cttccacata 2296081 caccgacatg atgccttctt ccgctaggat cttcaaaaca tcaggaattt gaatgcgctc 2296141 ggtttcaagt gtaaatatgt tcactccgaa agctgaaagc cgttttttct tttcctcgtc 2296201 tgcgcgtgcc gtcgtaaaaa tccatgtcgg cgctatttga tcgcaaatca ctttagcgtc 2296261 ctcaggaatc gagagtacgg tatcaagtat gacccgaacc ggctgttttg ttacattcgg 2296321 cagtctgcag gttaagctcg gattgtcggc tttcactgtg ccaactccga ctaaaatgct 2296381 ttggtgtgtt ttcctgtatt gctgagcatc ctgtcttgca gcctctgacg tgatccattt 2296441 gctgtcaccc gtgctggtag ctatcttgcc gtcaaggctg gcagccgctt ttagcgtgac 2296501 gtacggaagg cctgtcctca taaagtgcag aaatttttca ttcagcctct ccgcctggtc 2296561 tgccaggatg ccttccctta cctcaatgcc agcttctttc atcatgctga tccctcttcc 2296621 agccacaagc ggattaggat ctctcatcgc cacgaacact cttttgatac cagagttgat 2296681 aatcaattct gcacatggcg gtgtttttcc gtaatggctg cacggttcga gtgtaacgta 2296741 aatgtcggca ccctctgcat gtgctccagc catatggatg gcatgaactt ctgcatgagc 2296801 ttcaccatat tttaaatggg cgcccattcc gacaatttgt ccgtccttta cgacaacagc 2296861 gccgacgagc ggattggatt cggtctgtcc ttcgccctgc ttcgcaagat ctaaggccag 2296921 cttcatataa tactcttcca tttgtttccc tcccctcttt tgttatttac cgtcaaaaaa 2296981 gccccgaatt tataaaaaat tcggggcttt aggtatttta cgcaatagga aataacacta 2297041 tgcattttta aacattttgc atagcggctc atcatccttc tcccatccag actttcactg 2297101 tcggcttcag cttaaactga atccaccgcg tgcttatgca cacgggtcac gggctctaaa 2297161 gcaaatgtgc tttactaccg ccggtcggga tttccaccct gccccgaagg atacaatctt 2297221 tattcatttg tccttattgg ttattatagc gatccttttt aaagtacgca atgaaataaa 2297281 cttacaattt gagaaaaaca aaacatcacc cttcgatccg aaaggtgatg ttttttaatc 2297341 attcactttt gcaaccttga ttaatccgtc gatccgcttt gatttgctga agtaagcctt 2297401 aatcttgtca ccttctttta tatcagataa atcctgattt aatttttttc cgttgaagat 2297461 gattttcgtt ccgttttctg ctactccatg atactctgag ccgtcaattt tcgtcacttt 2297521 atattcctgg atggtgtatt cctcttcttc cgaggacaag gtttgtccaa ttgctgtcgg 2297581 aacatccttc agctcaatat catttatgta catataaccg cctgcaagta aaagcaaaag 2297641 cactaacaga atggtaatct tggtttttat tcttcccatt tctaaacctc cagccaatat 2297701 gaatctattc attcatatga gttattcctt tttttcatga ataaaaaacc gtaaattctc 2297761 gtaaattatt aatataacga tgcataacgg gaatatgttt cacatttctg caaaaatttc 2297821 ttttctatag atatacgaat ttatgttctg tttttagggg atgaccgtaa aaaagatata 2297881 aaaaaagcag ccccaatggg aagctgcttg atcctaattt gttttgcgca tttcgttaaa 2297941 cgggtagaaa acaaactttg acgtacccgc aatttgtttt ttcgtgaaga ggccaaggcc 2298001 gttacggctg tccatggaat tgcgacgatt gtcacccatc acaaaatact tgttatcagg 2298061 cactttaacc gggccgaaat catcggtcaa atggtcaaaa ccgtcctgtt tcgctctctt 2298121 tttattagcc gccaaataag gttcgtccac ctttttcccg ttgatataga gctggtcatt 2298181 tttcatctca accgtatcgc cgggaaggcc gataatacgt ttgacatagt gaacatcatc 2298241 tccgtttaac acgacgatgt ctcctctatc aaactcgccg atgtatttga ctgtcatatt 2298301 aacaaaaacc ctttcacggt tgtgaagtgt aggatacata gagtcaccat caacgacata 2298361 cggcgcaaaa ataaagttgc ggatgagcaa agcaagaacg acagcaatca caattgcttt 2298421 tgcccattct aatattgact ttttcttcga aacattttct gatttcaact gatttcctcc 2298481 aataaacaac ggtcttcaat ttatgttatc acgaatcgaa aaaaaatccc attaggacca 2298541 ttgaagtgat tttacaaact gttaatcttc atcttctacc cacatcatgc ctattttttc 2298601 ttgtcgatca taactaggcc tgaaaatatt gaaagaaatg aatcgcataa ttcagaagcg 2298661 atggactcag aagaaagaga gttctcatat gcaaaatctt tagatcgtat ataaagcatg 2298721 aggttacggg cagtttgttc atttactgca ttccattgat ctcccagtcc atgataccca 2298781 tggcacttga caaaacaatt aacgtcatga aggttactgg aatgtttgcg gcaacctatt 2298841 tcacaggtga taaccgcacc ccgttttttg ctttcataat atgtttaaaa tcattcaagc 2298901 tcgaaaacat ggatcagcct ccaaaaaata aatccaatat attcccggca gttgaagact 2298961 ctttattata aaactctgaa tatccgcagt tcttacagta aaccactaga aatcggttat 2299021 gctgcacgtc aaacagcttt gataatcccg tgccggttgt agctatttct ttttgtccgg 2299081 cttcagtact accgcatttt atacagcctt tgttgttcat atcgcgatct ccttttcatt 2299141 acatcacgtt tgtttgattt attttactac aaaatatcaa tcccaatgac ccgtactact 2299201 ttaaagttta cttaattttg attacatact aattgggttc gtttctcagc ttggtaaatc 2299261 ttctggagaa acggaaaagc tccatgacca aaacattcaa actcagccaa acaccgccga 2299321 aggcgtaacc cgcagcaaca tcactcggat actgctcata aagtacacac ggctcagccc 2299381 gatgaggaat aaaacgataa taaacaaaaa aatgcaacag tttgcagacg cgtcttgtga 2299441 gaatgacgaa caaaaagata agcacaaaaa ccaaaaatga caaatgccgt taaagtctgt 2299501 tcgctcggga atggatataa tacatgactt tccaaaggag cgtgaacagg atgaagggaa 2299561 tgaaagagcc gtctgattcc ctcttcataa agctccccac caatgactag gaaaaataag 2299621 aaagagagtt cgattttccg atcttgccct ctgaataccg tccaaaaaaa agttagaaca 2299681 ataacggcta acagaacacc tctcgacgca aaagctttct gaattgcagc tgggcccagt 2299741 ctatacccga tccaatacga catgctcact cccacagctc cccaatccgg ccgctaacat 2299801 gcttagcacc cagtttaact tttcttgaaa cacgagaaca ccggcaaact ctcccggtcc 2299861 aagtaaagct agaagctcta acatcaagac aataaacaag acggcatatc cgtactgttc 2299921 gagcaacccc gtcaaaactt gcatgtgatt ctccttaaac ttttttgttc ttttatcatt 2299981 cccaatccac tttttgtata atcagcacaa ttttatcttc agtcgtccaa caacattgtc 2300041 tatggcggga tcttctctca tacattcttt tttgacatag gaggagcaat agcatgaaat 2300101 gggaggaaac aaaagatacg cagggagttt gccaaaattt tgggcagttc gttctgccac 2300161 cgagtcaggt gtttgtttgc ccacctcatc ccttgtcaat tccccatttt tcccgtttga 2300221 ggttcgaaat ggtaaagtat ttcacttagt ttcttacatg aagaggtaaa ttctttgctc 2300281 accgaactag gatagcggcg tatggcgatt tctacattgc ataaccactg gttatttagt 2300341 gagccgtgag caatgtatat gcactttgag tcagcacagg atgatcctat tacattcgcc 2300401 agaaaagcag ctgccgcatt cagagtagtt aaaagaatag acagatatct gggcttccgg 2300461 aagctttaaa ggaggctctt ttttcgagca tttttataaa tcaataaaaa caggcatctc 2300521 ctaaatattt ttgccgataa gtttacgcta atcaactcta gcactaatac atataaaaaa 2300581 tagaatgata tgaaaggaga cttgatagta tgattgatta tcctattaat ataaacaacg 2300641 tttccgggaa cagtgtaatt aacgtaggcg gcgcttttat gatcaggcct ttaactttgt 2300701 ccaaatctgt gtttggctcc ggaggtttaa acacaggaat tgtctttgaa aataactttg 2300761 taagcaaagc taaaatgatt aatcatcaat ttactgatca aaacgtcacc aaaacttttt 2300821 aatgtattca atacacgggg gtcactaact aaacacctgg ttttgccaac cgccatcagc 2300881 attcggcggt tttttattga acatttttgg ccaataaaaa aagcttcctc tctaagagga 2300941 agccttttgc ctgccgatta gccttctaca cgaacttctt tcatgacatc gccattagac 2301001 atgtttttcg cgaattctaa tccgcttgtt actttaccaa atacagtgtg aacaccgttc 2301061 aaatgaggct gtggctcatg aacgatgaaa aattggctgc cgccagtgtc ttttccggca 2301121 tgtgccatag aaagtgcgcc cgcctcatgt gtatgcgggt tgccttctgt ttcacatttg 2301181 attgtgtatc ccggaccgcc tgtaccagtt ccgtgcgggc atccgccttg gctgacgaag 2301241 ccagggatca ctcggtggaa tgtaagcccg tcataaaagc cttcgttcgc aagcttttca 2301301 aagtttgcaa cagttccagg tgcagcttca ggataaagtt caaattcaat tttgttcccg 2301361 tcttctaata aaaagtaacc tgttttcaat tgtatgccta ctttctttat tttaattttc 2301421 aaaggagatt atgtataggt tatagcctgt ctctccttgt cgcggctatt ataccacacc 2301481 tttcggggga aaacgaatct cccgagcttt actaaaaaat aaaaatgaaa cctgaatctc 2301541 tttatctccg tctaacctaa cggaactgta tttttcatga ttcaggtcct cacaaagcag 2301601 cactatccag ctgcttgtga aattgaagga ggtcaaactg ctttgaagaa aatttggatt 2301661 ggaatgctgg cagcggccgt tttgctgctg atggttccga aggtcagtct cgcggatgcc 2301721 gcagttggag atgtcattgt aacactgggt gctgatttgt cagaatctga caaacaaaaa 2301781 gtgcttgatg aaatgaatgt ccctgataat gccacaacgg taaccgtgac caataaggaa 2301841 gaacatgaat atttaggaaa atatatatcg aacgcgcaaa tcggatcgag agcgatttct 2301901 tcatcgtcaa tcaccattgc caaaaaaggc tccggattga atgttgagac ccataatatc 2301961 agcggcatca cagatgaaat gtacctgaat gcactgatga cagccggtgt taaagatgcg 2302021 aaggtgtatg ttacagcacc gtttgaagta tccgggactg ccgctttaac tggattgatt 2302081 aaggcgtatg aagtttcttc tgacgaagcg atctcggagg atgttaagca ggtcgccaac 2302141 caagagcttg tcacgacatc agagcttgga gacaaaatcg gtaacgaaaa tgcggcagcc 2302201 ctgattgcaa aaatcaaaga agagtttgct aaaaacgggg tgcctgataa taaagctgac 2302261 atcgaaaaac aagtggatga cgcagcttct gatttaaacg tcacacttac agacagccaa 2302321 aagaatcagc ttgtctccct attcaataag atgaaaaacg ctgacattga ctggggacag 2302381 gtcagtgacc agctagataa agcgaaagat aagattacga aattcataga atcagatgaa 2302441 ggcaaaaact tcatccagaa agtcattgat ttcttcgtat ctatctggaa tgcgattgta 2302501 tctatattca aataagaaaa gcgccgaaaa atcggcgctt tcttttattg ctttacaccc 2302561 gttttaaatg gcagatcaag ttttacaata tcttcgtatg tttctcgctt cacgactaaa 2302621 tgagcctcac cgttttcgac aaatacaacg gcgggtctcg gaatacggtt ataattgttg 2302681 gccatgctgt atccataagc gcctgtacaa aaaacggcaa gaagatcgcc ttcttttact 2302741 tccggcaggt caatatccca aatcagcata tctccgcttt cacagcactt tccggcaatt 2302801 gataccgttt tgtcatgcgc ttctccgatc ctgttggctg ccgcagcttc atatttagct 2302861 tggtaaagcg caggacgaat attgtcgttc atgcctccgt ctacagccac atattggcgg 2302921 acacccggca cttctttttg agagccaacc gtataaagag ttgtgcctgc gtctcccacg 2302981 agagaacggc ccggttcgat ccaaatttcc ggaatgtcaa aaccgtaacg ggaagcattt 2303041 tctttcacag cttcgataat tttttcaacg tattcagtgg catgaagcgg ttcatcatct 2303101 tccgtataac gaatgccgaa acctcctcca agattcagca ccttggatac aaatgaatat 2303161 gaatctctcc attcgtctag ttttttgaag attttttccg ctgctaacac aaaaccggcc 2303221 gtatcaaaga tttgcgagcc gatatggcaa tggacaccca gcagctgaat gtgttccgat 2303281 tgtaatactt gttcaatggc ccgttcagtt tgtccgttat gaagatcgaa accaaacttt 2303341 gaatcttcct ggcccgttgt aatgtagtca tgcgtatgcg cttctactcc gggcgtgatc 2303401 cgaagaagaa catcgatgga gtgacccgtt tctttacata ggtcttcaag aagcgcgatt 2303461 tcatagaaat tatccaccac aatgcagccg atgcggtgct caagcgccat ccgcagttct 2303521 tccctgctct tattgtttcc atgaaagtgg atgcgttctg ccggaaagcc tgctgcaaca 2303581 gccgtatata gctctcctcc ggatacgaca tctaaagaaa gtccctcttc ctcagcgagc 2303641 tgaatcattg cgactgatga gaatgctttg ctcgcatatg ccacctgtgc tttcagccct 2303701 gcagaaataa acgcctgctt aaagctttta gcacgctcac gtattaaagc cacatcatat 2303761 acgtaaagag gtgtaccata tttctccgct aaatagagag catccacacc tccgatttct 2303821 aaatgaccat gttgattttg tctgcttgtg ccgtgtaaga acaatgtcat tccctctttc 2303881 tccgcttatg gatgaaagga cagttttatg gactgtccct tcataattaa gacatacatt 2303941 atcatactct tcagtcagtt tcaatgcgat tatgaattgg taggctgcct taagcgattt 2304001 ttggggtgaa cgatgctggg tcttactttt gcgccaggtt tcgctgtgcg gacaagaacc 2304061 tgccacagcg cctttccgtt aaagggaatc agcggccata agtacggtgt ctgaagggat 2304121 ttgatgcttg ccatggcaat aattagcact gtaaatccga tgacgagccc ttttatatga 2304181 aataaagcaa cgagtatcat gaggacaaga cggctcattt tgtttgccaa gcttaattca 2304241 taactaggcg tcgtaaaggt tccaatcgcc gcaagtgaga cgtacagaat cacctcagga 2304301 gaaaaaaggc cgacctcaat cgcaatctgc ccgatcagaa cagcggcaat taaacccatt 2304361 gctgtcgata aagccgtcgg tgtgtgaatg gcagccattc tgagaaactc gattcctaag 2304421 tcagctaaaa atatctgcag gatgatcggg atatgcgtat ctttatttaa accgataaat 2304481 ttcatgttgt ccgggagcag atcaggctga agcacaaaga gaaaccagat cggaagaaat 2304541 aaagtagaag caagaatacc gaaaaatctt acccatctta aaaaggtccc gactgaaggc 2304601 gcctgcctat attcttcagc atgctgcaca tggtgaaata aagtcgtcgg ggtaatgatc 2304661 acactcggcg atgtgtccac tataatgata acatggcctt ctagaacatg atttgcggcc 2304721 acatccggtc tttctgtata gcgcacgagc ggaaaaggat tatagctttg attaacaatg 2304781 aattcctcga cagttttgtc tgccattgtt aatccatcga catcaatgga tgcaatttct 2304841 ttttctacga tctcaaccag atccggatca gctatatctt ctatataaca aatgcttaaa 2304901 tccgtctttg accgctcacc aactttagtc atcttgactc gaaggcgttc gtctctgatc 2304961 cgccttctga gaagggccgt attgacgacg atattttcaa caaatccgtc tctggctccc 2305021 ctgaccacct tttccgtatc aggttcttcc gggtttctgc ccggatagct tctgacatca 2305081 attataaatg cgaagcctgc accttcaaca atgacagcga cgagcccgga cagcacttgg 2305141 tcggtggttt catccaaggt ttttactttt tcgacctggg cgttaagcag cctgttttcg 2305201 acgatgtcga ccagctcatc agggtcttct ttccgattgt taatggcaac aagctctctc 2305261 attaaatgaa taatataggc tgtatcgcat aatccattta gatagtaaag ctggatctct 2305321 ttatctaaaa tcgtgagctt gcgaacacct acatcatagc tcgtccccat cccaacacgg 2305381 tttttgaaat actcttcatt tttagctgga ttccgataaa cccgaatttt ctcttccttg 2305441 tggtccggca tgatacccgc tcctttctaa aataaactcg accgctttca tggtgattgg 2305501 cgaccctttt gagatatcgt cttttctgcc cattttgccg atatccccga taccgacaat 2305561 aagcgggaga tcaagtttat caaggcaata gactgtatct ccactcattc tgtggtcatc 2305621 aaattccctt tccccgactt tatcgacgcc gtattcagtt atttctccat tgcggtcaat 2305681 gcttacatcg accctggtcc attcagcctg atgtgttttt gacgcgaccg caatcacacc 2305741 gagcacttca atagacggat gggttgcgac ataggttaga gcggcttctc ccgggccctc 2305801 tccttgaagg ccggagtcgt caaacatgac aaatacagga tcatacggtg ctgaggcgat 2305861 cagcttgaca agctcggcgc cgctgcgggt ggaaggattc ccttttgatt gtgaaataca 2305921 tcggcctccc actttgcttg cggcgtattc aattgtttta gcggcataaa catccccgtc 2305981 tgttaccagt atgaccttgc gttttgtcgt catgtcggca ttatcctttc ggtttgaaaa 2306041 taacagctac gataaaggcg aaaagaatag cggctgagat accggccgag gtcagctcaa 2306101 aaatccccat gccgattccg ataaatccgt gtatatgcgc ctgatgcatg gcgccgtgca 2306161 gaagactgtg accgaagctg acgatcggaa cggtggcgcc tcctccggca aattcaataa 2306221 atttatcgta aatgccgaaa ccatctaata ttgcaccgat tacaacaaat gatgtcatga 2306281 catgagctgg cgtcaattta aaaatatcca agagcagctg gccgacgata cagatggccc 2306341 cgccgcagac aaaagccaaa aggtagtcca tattaagatg cacctcctgc acgctcaaat 2306401 acaaccccgt gggcgatagt cgggatggtt tctttttgct ggatcatcgt cgggcttaat 2306461 agcgccccgg tcgccacgac aaatacacgg tttagttttc cttctctcag ctgcttaaaa 2306521 atatgagagt aggtgacaac cgctgaacaa gcacagccgc tccccccggc aaagacctgc 2306581 tgatccggag tgtaaatcag aagcccgcaa tcatcatgct ttgtgccgac tggatatcca 2306641 tcttctttta aaatgtcttt tacgattgga gaaccgacgc ctgacaggtc acctgtcagg 2306701 attagatcat agtcatccgc tgtccggttg agatctttaa agtgctgctt aatcgtatca 2306761 gctgcagccg gagccatagc cgatcccata tcaaaaggat ctgtaattcc taaatcagaa 2306821 accttcccga cagtcgcact tgtgatttgg atatcacccg gtgtctgact gatgacaact 2306881 gcaccgcttc cggttacagt ggaggtagca gtgtccggtt tttggcctcc gtattctgtc 2306941 ggatagcgaa actgtctttc cgcagttgca ttgtgactgc tggtggcagc gagtgccctt 2307001 ttggcaaacc ctccatcaac taaggctgat gcgacagcca ctgtttccat tgatgttgaa 2307061 caggcgccaa acatacaaag aaatgggatt ttcaagtgtc ttgccacata gttagccgtc 2307121 acgttttggt tcagcaagtc gcctgccagc aataggtcaa tatcatcttt tgtcagattg 2307181 tttttttgaa gtgcaacatt aacagcgtct tccatcagct gccgttccgc catttcccag 2307241 cttttttgat tacaatgcat ttcgtcatag gttttatcaa ataaagagcc aagcggtccg 2307301 tctttttcct ttggtcctgc tgccgttccc gctgagttga caaatatggg atgttcaaat 2307361 acccaggttt gctttcctgt taatttcatt ttcttctcct cctatgacat cagtttctca 2307421 aaagcaaacc gaatcattcc aacgatgtat gcagctacaa ctccgaaaac aataacattt 2307481 cctgccagtt taaacatatt tgtcgctact ccaagcacta atccttcgct tttatattca 2307541 agagccgcac ttgccatact gttggcaaaa cccgtgacag gtacggctga acctgcgcct 2307601 gcgaattgtc cgattctgtc atagattcca aaccctgtaa gcagggcaga aattaatatc 2307661 agcgttgcag ctgttggatt ccccgcagtt ttttcattga aatcaaaaaa atggatataa 2307721 aaattttgca gaccttgccc gattgcacaa atcagtccgc ccactaaaaa ggcttttaca 2307781 cagttccaga cgtaaggcgg cttaggctga tatgttttca cttttgattt gtaattttct 2307841 tttatgtttg tcatcttgaa acctccttat gaatggtcaa taaagtacag ccagtgaaat 2307901 aaagatcccg cgattttccc aatcacgatg gccattaaca gaataatgat tttacttctg 2307961 agcccgattc gtttcgccaa aatcggcagg acatttaaaa cctctgtaag agcagccgct 2308021 agcatcccga cgaacaaacc tgccagaagc ccgaccggca cagctatcca ttttgttaga 2308081 taaagatgat tcatatgaag cgtctcccat cccccgcaaa ccgcgccaag aataacagcc 2308141 gcttcataag cctgaacaaa tctcattgtt ttggtgagct gcatcagccg cggaatgatt 2308201 cccattacgg ttaaaaaagc aacgaaaccc gcccccaccg ttatgcctcc gccgagcccg 2308261 acaaaaatga tgaacaatac actaacgatc atgcagatcc tttatggttt cttgattctc 2308321 atgcatggcc acatattgat cgagatcaag ctgatagtta aacatctcaa cctccagcgg 2308381 gctgggctct tcatttaggc gctttttaaa tatgtggtta aaaaacacga tcatccccag 2308441 tcccaaaccg atgctgtatg ggatttgaag caaatatgga tagtcattcc tctctccggt 2308501 tatgatttca tatagtgcga tatgaacatc tctcatgctt acatcctcat gaaagttcat 2308561 gatggcaaga cacgatccaa taaacagaag cagccagaca ccgataaata gaaccgttga 2308621 taaatttcgc tttcgatact gaatttcaac aatggtttct gctccgccta cggtttgaac 2308681 atcaattgtc gggtcttgta aatgaatggc tctgaggact tgtatgatat ccagaattac 2308741 gatattttta tctttttcgc tcacctgata aagcggcata gccgaaagtt tctttttcag 2308801 ctgaagctgc ccttctattt gcgcggcatc tccaacggta ataatatccc ctggatgtgc 2308861 cagcactcgg tggcgaagcc ggataaatat tcgtcgttcc atcattgatc accatctttc 2308921 ggtggttata tatgtagtat gtggttcgat tttgttctca ttcatccgct cgaaaagacc 2308981 ataaattacc acgcttttgc acaaaaaagc tagcctgcac tgcagactag ccatccgtat 2309041 gatccatttg aaccttgatc tgttttaata ttttcttttc aagcctggaa acctgcacct 2309101 gagagatccc gagccgctca gccacctcgg actgtgtctg gtctttataa tatctgagat 2309161 agacgattag tttttccctt tcctccaaat cgctgatcgc ttctttcagc gcaattttgt 2309221 caaaccattt ttcttctgag ttgtcagcga tttgatcaag cagggtaatc ggatctccgt 2309281 cattttcata aacggtttcg tgaatcgaag atggagccct taccgcctct tgggccagta 2309341 caacatcctc agcttcaatc tccaaatggt cagcgatctc ctgcaccgtc ggcactctgc 2309401 ccagtgtttt cgaaagctca tccttcgcgc gccggatttt gtttccaagc tcttttaatg 2309461 accgtgatac ctttacggtt ccgtcatcac ggataaatcg ttggatttct ccgataatca 2309521 tcggcactgc atacgttgaa aaacgcacat cataggttaa atcaaatttg tcaacagatt 2309581 ttaacagccc gatgcagccg atctggaaga gatcgtcagg ctcatatcct ctgtttaaaa 2309641 accgctgtac gacagaccaa acaagacgca tgtttttttc tatgaggagg tctcttgcct 2309701 gctggtcgcc attttggctt tgtttgatta attcctttac ttcatgatcc ttcagctgag 2309761 cgtttttgcc gtttttctta acctccacat ccataacaaa tctccttaat tacaaagcgc 2309821 tttgcttttt gataagtgct ttgttaagcg aatcgttgtt cccatttcag gcgatgaatc 2309881 gatactgaca tcatccatga aattttccat aatggtaaag cccattccag agcgctcaag 2309941 ctcaggctta gtcgtaaata gaggctgacg ggcttcttca agatctgtaa tgcctaagcc 2310001 ttcatcacga atagtcatat atacgacatg atcttccagc gtcactgaaa tgtaaacttt 2310061 cccttcacag ttctcttcat atccatggat aatcgcattc gtgacagcct ctgacacgac 2310121 tgttttgatt tcagtcagtt catccattgt cgggtccagc tgagctataa atgaagcaac 2310181 tgtcacacgg gcgaacgatt cattctgact gagggcagaa aactcaaggt gcatttcatt 2310241 tttcatgatg ccacccccag tgtcaggagt gcctgctgtt cagattgttc aaatcggata 2310301 attttaaaca gacccgacat atcaaacaat cgcttcaccg caggagagat agcgcaaaca 2310361 accatttctc cgccaatttg cttaatttgc ttgtatcttc ctaaaataac gccaagcccc 2310421 gagctgtcca taaaggaaag gtcctccaag ttcagcacga tatggcgaat atcatccttc 2310481 tccaatgatt gagtcacttt ttgcttcagg gtttcagccg tatggtgatc gagttcgcct 2310541 gttaatcgaa tacaaagcac agattctttg acattcatgt caattccaag gctcatgctc 2310601 attcctcctt gatatgatcg gataatgagt gtttcgattt cgacggaatg aattccttca 2310661 ccgtgacaaa actagtggtc attcggcata attacttaaa ttttgtccag tctcccatcg 2310721 tccgctttaa gaatgtgata aacccggctt tcttcatatc ttcttttgca gcaacaggac 2310781 tttcagcgag tacttctcca tcctttttca gaacaagagt gccaagctct tggccttttt 2310841 gaatcggagc actaatattg tccttcatct tgatttcttt tttcacatcg ttcatatcct 2310901 cgcctttttt cgtcaatatt gaaatcggct cagatgtagt gagttcgata aatttttgtt 2310961 tccctttttt gacctttact tttgctactg tttgatttcg tttatataaa ggatgcgttt 2311021 catattggct aaaggcgaag tcaagcattt ttgtcacttg cgcgtttctt tctttaggcg 2311081 tgctcgctcc gaatacaacc gctatggccc gcatgtttcc ttttttagcc gaagcagtca 2311141 gacaatattt cgcttcgcct gtatagcctg tttttacgcc gtctacacca ggataaaatt 2311201 tgataaggcg atttgtattt acaagccaaa actttttatc tgtattttca cgcagataat 2311261 cttcatacgt gccggtaaac ttcgtaattg attcgtattt caataattcc ttagccatga 2311321 ttgccatgtc ataagcagag ctgtagtgtc cttcctcggt cagtcctgtt gggtttttaa 2311381 aggatgtatt tttcaatccc agctcttttg cttttttatt cattttcttc acaaattctt 2311441 cttcagagcc ggaaataaat tcagccatgg cgacggaagc gtcatttccc gaagcgattg 2311501 cgatgccttt cagcatttct ttgacagtca tttcttcgcc gggctcaagg aatatctgtg 2311561 agccgcccat tgacgccgca tgctcgcttg tacggacctt atcactcatt ttgattttgc 2311621 ctttatctaa agcttccata atcaaaagca tcgtcataat tttcgtcatg cttgcaggcg 2311681 ccagtctctc attgctgttc ttgttgtaaa gcacttttcc cgtgtcacgt tctatcagca 2311741 ccgcagactt cgcttcatga gcaagctccg atgtacgttt tccgtcttgt tttgcaaatg 2311801 cagacggtgc aaatgtaagc agcattatac caatcaacaa agtggataaa agacgtttca 2311861 tctcaaaagc cctccatttc ataatccttt ttattttttc caagcgtgat ggttttatac 2311921 gccactgatg gaaaatgttt cgaattttgg gcataaaaaa agacagctgt gtgatatcag 2311981 acacagctgt cttttggtcc tgcattgatt catatttatt cgtactgagc gacgatcgct 2312041 ttaacaagct ttaagaatcc agcttttact ttttcggtca cttccataac ttcatcgtga 2312101 cttaaaggct gatccagaat tccggctgcc gcgttagaga tgcaggaaat gccaagaacc 2312161 cgcattcccg catgattcgc tacaatgact tccggaacag tagacatgcc gactgcatca 2312221 gagcccatcg ttcttaagaa acggacttct gccggtgttt cgtaagaagg tcctgtcaca 2312281 gcagtgtaca cgcctttttg aattgggata ttaaggtctt tcgcaatctt ttcagccagg 2312341 ctggacagat ctttgtcata ggctgaagac atatctggaa atctggcgcc gaaatctgct 2312401 tcgtttggcc cgattaacgg gtttgttccc ataaagttga tatgatcggt aataatcatt 2312461 aaatctcccg cacggaattc agtgttgaca ccgcctgcgg catttgtcac gatcaacgct 2312521 tccacaccga gcgctttcat cacgcgtaca gggaatgtga ctttctccat tgagtagcct 2312581 tcataaaaat gaaagcggcc ctgcattgca atgacggaaa ctccttcaag agtgccaagc 2312641 acaagctgtc cggcatgccc ttcaacagta gataccggga attcaggtat atcttcatat 2312701 ttcagcttga ccggattttc gatttcgtcc gccaaaatgc caagacctga gcctaaaata 2312761 aggccgatct ttggagattc cggcaggttt tgtttaataa aagcggctgc gcgttcaatt 2312821 ctgtccttca agaaacagtc cccctattgt aataaagata aaaagctttt cccgtatttc 2312881 ggtttatttg tttggaaatt atcagcgatc gttgcgccaa tatcggcaaa tgtatctgca 2312941 agcggcagca tttgcgcttt cttatgtttt ttgctgtaag cgagaatcgg cacatactcg 2313001 cgtgtatggt cagtcccatg atgaatcgga tcattgccgt ggtcggctgt aataattaac 2313061 agatcgtctt ctctcatttt ttcaaacact tccggaagcc gcgcatcaaa ttcttcaagc 2313121 gcgcgtccgt agccttcagg gtcacggcgg tgtccgaata acgcgtcaaa atcaacaagg 2313181 ttcgcaaagc tcagacccgt aaaatcttct cccagcgtat cgatcacctt gtccattccg 2313241 tccatattag aaaccgttct gcgtgaagaa gtaatgcctt ctccgtcgta aatatcagag 2313301 attttaccga ttgaaatcac atctaagccg cagtctttca attcattcat gacagtgcgg 2313361 tcaaacggct tcagcgcata atcatggcgg tttggcgtcc gtttgaattg acccggctct 2313421 ccgacgaacg gccgtgcaat aatgcggcca accatatatt tcggatcaag cgtcagctct 2313481 ctcgccgttt cgcaaatgcg atacagctcc tcaagcggca caacctcttc gtgagcggca 2313541 atttgcagaa cagagtcagc agacgtgtaa acaattaaag cccctgtctc catgtgctcc 2313601 tggccaagct catccaaaat cgctgtgccg gaagccggct tgtttccaat aattttgcgg 2313661 ccagatctct tttccagctc ttgaagcaat tcatcaggaa agccttccgg gaacacttta 2313721 aacggtttat caatgtataa acccataatc tcccaatggc cggtcatcgt atctttgccg 2313781 tttgacgctt cttgcatttt tccataatag gcaagcggat gttctgtttt ttctacacct 2313841 ttgatatctt cgataagacc aaggccgagc tttgccatat tcggcatatg taatccgttc 2313901 atatgctcgg caatatgacc gagcgtatga gcgccttcgt cattaaagtc agcggcatcc 2313961 ggcgcttcgc cgattccgac tgagtccatc acaattaaaa acacacgatt atatttgtat 2314021 gcaggcatct tgaaagcctc ctttttttct atacgtctat tgtatcgcta agaggtctga 2314081 caactcaagt ataaaccgtt ttcattcccg ttgacaatgt atttggaaat aatgagaaac 2314141 ttcaatattt tctgtcgctc taaacaaaaa agccgcagcc acctgcggct atgctcgcgg 2314201 atgaaactgc ttgtacacat ccttcagcct tgttttcgtc acatgcgtat aaatttgcgt 2314261 cgtggatata tccgcatgac cgagcatttc ctgcaccgct cttaaatctg ccccgttctc 2314321 aagcagatgc gtcgcaaagg aatgcctgag tgtatgcgga gtcagctctt tcttaatgcc 2314381 ggcttccaat gcgatttttt tcaggttctt ccaaaatccc tggcggctga tctgtttgcc 2314441 gtgatgattt aaaaagaggg cgtcagatac attatttttt aacagttttc ccctggcttt 2314501 tgtcatatat tcctcaatgg cggaagcagc ggcttcaccg attggcacaa tccgttcttt 2314561 tcttcctttg ccgaagcatc ggataaaccc catagataaa tgaacatcag ccgttttcaa 2314621 ttcaatcatt tcactgactc gtatgcctgt cgcataaagc agctccagca ttgctttatc 2314681 ccgatatccg aaagggctcg tcagcttagg cgtgtccaat aaccgctcga cttcattgag 2314741 cgcgagcacc ttcggaagcg cccgttccgt cttttgtgtt tcgatatgaa cggaagggtc 2314801 cttatccgtt actttttccc tgagcagaaa ttgatgaaaa gagcgaatgg atgccaaatg 2314861 ccgcgccgat gtcttgccgg atttccccga gtccttcaaa tgctttaagt attggataat 2314921 atgtatgcgg gtaacgtgat tccaatctgt aacatgaagg gtttctgtta agtagagaga 2314981 atagcttttc aagtcacgtt cataggatac gatcgtattt tgagagagcc ctctctctac 2315041 cataacgtag tggatgaaat cctttatttg atctttcact cttgatctac tccccgtttt 2315101 ggtaaaaaaa gatcaaccgg tcgaaccatc cgcctttttc atcctgatcc atttcaacaa 2315161 cttttacagc ggagccttcc ggtttatcat accgatgata gttttcatac tcttgattca 2315221 cccatatcat agcataatag aacaaagcgg taaaaccggt aaacaggatg aaaactttca 2315281 atgcatcgac agctgttttc aggaatcttc ccatgtccta atcgatcctt tccctatggt 2315341 tccagttata taaaccatat gccaaatcag aaaggtttta tacatagaaa cagcaaaaaa 2315401 ccctttcccc atgagaaaag gttcgcgctc ggcaccgtct attcagtttc ttttccgtta 2315461 cagcggtggc aaatgccgtg aaacgtcaat ctatgatctt taatcttaaa tttccaatca 2315521 cgttcaatga tttcttccac gtcttcaagc aaatcttctt caatttcatc aacggctccg 2315581 cactccatgc acaccaagtg gtgatgaaag tgagctgcgc cctctttccg aaggtcgtaa 2315641 cgggacacac cgtctccaaa gttaatttta tctacgactt ttaattcagt taataattca 2315701 agcgtacggt atactgtagc gagaccgatc tcaggagatt tctcttttac gaggaggtat 2315761 acatcttctg cgcttaaatg gtcttcttcg ttttcaagca gcactcttac tgtcgcttca 2315821 cgctgtggcg taagtttata gctggatgag tgcagttgtt tcttaatacg atcaatacgg 2315881 ttttccatgt ctttccctcc tacgccgcat tccatgactc attataacaa aatacgcgca 2315941 gagttccaac tataattatt ataaactgat aaataaaatg gttttctttt aataatgatt 2316001 ttaaaaaagt ctagatgtaa gcttttccat taaaacagga gataagtatg cttcaaagag 2316061 agatgaaatc agcgctaaaa acagaatgac cagcagcaca aaggcatacc gcccgaacca 2316121 ttgaatcggc gcgtcatgca ggcttcgttt cacgaacagc tgtctgatta actttaaaga 2316181 aaacgcaatt gcacatgtgc ccataatgag ataagccgga atcagcagca cattttgcgg 2316241 caaaacggag acaaatgata ggaaaaaccc gcttactccc atctgattga ctaggaaccc 2316301 gacagtaaag ccgacgacga tccctttcag aaagatcata atgaaaataa tcggcatccc 2316361 aatgacggaa attcccagta tccacatcag gcctaaatac tttgcattat gaaagatact 2316421 ttgcccaaac atatcagctg aacttgcctg ttttccatcc gaaagctgtc caaaaaattg 2316481 acttaagtag tagtataaat cttctttctg gctgatggtc atactgttga caataatcgc 2316541 gccaaagatg acacccatga aaaacagcac tgacacaaat atataaagag agagatgatc 2316601 tttgacatgc ctgagaaaca tgtccttata agagattttt cgcataccgt ttcctcccgc 2316661 ccgctctagt gatttgattt aatagattgt atgaaagaaa cagaaaaaca tgcccttttt 2316721 caaaaagaaa caatagagat gaatgctagg cggctttttg gggcacaaaa aaatccttat 2316781 catcaactgc tgtatgatca taaggattct tatgcttccg tttattcaaa atctcttttt 2316841 tgctttttgt cattcttcca tgtgtgctga aagatggtgt gctgcctctt gataataaga 2316901 cgtcacgtcc gccgtttctc aatcgatgcc cccgcttctt tttcgcttgg ctttttgcca 2316961 tgtgatcact ccctttttta ttttcatagt aatgataaca aaattgaaca atgataagaa 2317021 aaaaacagca cctgctacga caggtgctgt ttagctacat ttatttcact gctgtaagag 2317081 ctgcatgctc gacagctgct gctaccgcat gatggacttt tgaatcaagc ggctgaggga 2317141 caacatcacc ttgtttagtg caagctgcga tggcctctgc tgctgcgaca agcatatcat 2317201 gattaatctc cgtgcttttt gcgttaagcg ctcctctaaa aatccctgga aaaccgagta 2317261 cattattaac agaacgcccg tcagctgcat atgcggcgcc agcctgcagt gcggcctccg 2317321 gctcaatttc cggcttcgga ttcgataaag ccagaatcac ttgaccagaa cgtacaaatg 2317381 ccggttttat taaacccgga acgcccgttg tagcaatgac aatatcacat gtttccataa 2317441 gctcctcaat actggaaact gcctgtccgc cgtattgttc gagacggttc attgctgact 2317501 ctgatttgtc tgttccgtat acagcattca caccataagc catgaacatc cggcagatgg 2317561 ccacgcctgc tgcgccaagg ccgatttgcc ccactttcgc ttccttcagg tcaacccccg 2317621 cactcctgca tgccgaaatg gcagctgcca gcgtcactac agctgtacca tgctggtcat 2317681 cgtgcataac agggatgttc agctcctctt ttaggcgatc ctcgatttca aaacaatgcg 2317741 gcgaaccgat atcctcaaga aggatgccgc taaagcccgg agaaatatgt tttactgttt 2317801 tgatgatttc ttcaggatca ctcgtatcaa gcagtatcgg aatgccgcta atacccgcca 2317861 gctgatcaaa taaagcagcc tttccttcca tgacaggcat gccagccaca gagccgatat 2317921 tcccaaggcc taaaattgcg gttccatccg ttacaattgc aacagaattg ctgatcgttg 2317981 tataaataga agctttttca ggttcttttt cgatcagtcg gcacacgtcc gcaacacctg 2318041 gtgtgtagac acgtcccagc tctgccagtg aacggatcgg cattttgctt ttcatttgga 2318101 tttttccgcc ttcatgtgcg gacaggactt catcagatac ggtgtgaagc ctgatccctt 2318161 ctccgagggc ctgtacagcc gcgatcactt cctgaagctg ttcttcattc tccacttgaa 2318221 cggtaatatt ccgcattgtg taattgggtc cgacttttac cgtctccact tcaccaatat 2318281 ccccgcccag aaggccgatg gccgtagcca cccttccaag atttccggga accgaaggcg 2318341 tttcgatcat cagtgtccga atcatgtgtt tcgctatcat tcagtgatcc tcccctatta 2318401 gcctagtttt tcggctttaa ctgtattgtt tttcgtatac catataaatt ttcctgtata 2318461 accatagata attgcaagac ctattgctac aaaactgagc cacataaacg gcagataaga 2318521 gaaggtagaa acacctaaaa taccagccat gtaaatccca ttatcagacc aaggaaccat 2318581 ccccgaagtc aatgttcccc cgacctctga gttacgtgat aacactcttc tgtccagatg 2318641 taagcgatca tagctgtctt ccataatttt cggagtcaaa ataagagata catacatcgc 2318701 acagccgaag atgtttgcta aaaacgctac gatcagtgta gacaatgtga cattgccggc 2318761 tgaagttaat ttcttttcaa acgttgaaac aatgactttt aacacgccga gtttctcaag 2318821 cagaccgcca aaaccaaggc caaagatgat gacgacgaga gaatcaagca taccgacaat 2318881 tccaccgcgg tttaacaagc cgttcaaaaa ttcaacatcc gttttaatag agaagccgtt 2318941 gtacgcagtt gcaatcgcat gggcaatatc cattccttgg aaaacaacag cccagattgc 2319001 accgagtaaa gcgccaatta cgataactgg catagatggc tttttcatcg ccaataagac 2319061 tatgacgaga actgccggga tcagcatcca aatatgaatg tcaaacgtgt tttgcaaaga 2319121 tgattttaag aattcaactt tatcaagatc aatatttttc ccgccgtaca taaatccaac 2319181 aactgtaaag agtatagctg taatgacata agcaggtatt gataaataaa gcattgctct 2319241 cacgtgagcc aatacatcga cttttgatag tgaagaagct agaactgtac tgtcagacag 2319301 cggagacagc ttgtccccaa aataagcacc tgaaagaata gctcccgcta ctagaggaag 2319361 cggaatgcct aacccctctc caattgcgat catggcaatg ccggcagttc cgactgttcc 2319421 ccatgacgtt cctgttgcca cagacataat ggaacaaata attaacgttg ccagtaaaaa 2319481 gatacttggg tgaataaatt ccagtccgta ataaatcaaa gtcggcacaa cgcctccggc 2319541 aatccatgtt ccgatgagcg ccccaactga aacgagaatc agtacggctt caaggccatt 2319601 tgatatccca tgtacaatcg cattttgtaa atctttataa gaataaccga gtctaatacc 2319661 taaaagcatt gcaataaacc atgaaacaaa aagcgccagc tgtatcggca agtcgagaaa 2319721 gactgtaaac gatagaacaa gtgctaaaaa tactcctagt acaataataa tttcaaatag 2319781 tgttggcaat cttacatcct tcaaaagaag tcccccttca tgtaaaagct aaaacgcttt 2319841 caatatatag tgcaacacgt atactatact tcctcatccc tatgttgtaa acagcttatt 2319901 catccgacta ttcggagatg aataagctgt attttataca aattttattt ttctaatagt 2319961 tctttccctg cgatacctgg tttggtcatc tcatatgggt ttaaaataat atccaattct 2320021 tcttcagtca gcacatcatg ctgcagacaa agatcccgga cagattgccc tgtcataatt 2320081 gcttccctgg caattctagc tgccgcttca tacccaagat gcggattgac agctgtgatc 2320141 acgcctgcgc ttttttctac gtattgcttc atacgctttt cgttggcttc aatgcctttt 2320201 aagcagttgt cagtgaacga acggaagccg ttgttcatga tgctgatgga ttgaagcaaa 2320261 ttaaagacaa gcacgggctc catgacgttc aactcaagct ggccggcttc tgaagcaagg 2320321 cagattgtat tgtcatttcc gataacctgg aacgcaattt ggttgatcag ctccgccata 2320381 accggattga ctttccccgg cataatagat gaacccggct gacgtgcagg cagagaaatt 2320441 tccgcaagtc cggcgcgcgg tcccgacgcc attaagcgca ggtcgtttgc gatcttcgac 2320501 atgttcatca tgcagacttt taatgaagct gatacctctg tataggcatc tgtattttgt 2320561 gtcgcatcaa caagatgatc agcgccgaca agaggaagcc cgctaatatc agcaaggtgc 2320621 tttactacct gtttgatata ttcaggatca gcgttcagcc ctgtaccaac agcagttgcg 2320681 cccatgttga cttcatacag gtgctggcgc gattgcttga ttcgtttgat atcacgctcg 2320741 agaacacggc tgtaagcttc gaattcctgg ccaagacgga tcggaaccgc atcttgaagg 2320801 tgtgtccggc ccattttaat aacagagtca aactcctgtg ctttttgctt aaacacacta 2320861 tgcatatctt ccattgtttt cagcagtttt tctaagagct tcaatgtgga aatatggata 2320921 gcagtcggga acacatcgtt cgtagactgt gacatgttca catgtgtgtt tggacttaaa 2320981 tggatataat ctcccttttt atgtcccatg atttcaagcg cccggtttcc gataacctca 2321041 ttcgcgttca tgttcataga agttccggca ccgccctgaa tcggatcgac gataaactga 2321101 tcgtgccact tgccttccag aatctcgtca gcggcttgta cgatagcttg gccaattcct 2321161 tcatacagcc gtttcacgtc catgttggca agagccgcag cttttttcac aatcgccagt 2321221 gcgttaatca tttcctcatg gattttgtat cctgtgatcg gaaaattttc agaagcacgg 2321281 agcgtctgaa ttccgtaata aacatctgct tcaatttgtt tttccccaag gaagtctttt 2321341 tccacgcgat attctttttg gccgtttaac ataatcttta accttctttc tctttgctgg 2321401 ttatcgtttt tacattttac aggacaacgt catcagctat cggcgtttcc ataattctct 2321461 tgacgacagg aagatccgaa gactgaccta gcgcccacat caattttggc acaattgctt 2321521 ctgtgttcat atttcttgat cggataatta agtcttggtt gactctgcgg ccaacctcgt 2321581 aaatgctcat gtcttcgcct tcttcaagac attgagtcgt aatgacgacg acaatgccgc 2321641 tttcgatcag ttcattcact tttgacaaaa tgtctctgcc ttcaaacggc actcctccgc 2321701 tgccataact ctcaatgaca attcctttgt acatgctttt cagggcatca aacatttcgg 2321761 gctttaagcc tggatgcagc ttcagcagac atacatctgt gcatagtgaa gtgtcaactg 2321821 tgaaggtgtc gttctcaggt tccgttactt gtttgttgta ttcgatcccg tcttcattga 2321881 taaaagcgat atatgggtaa ttgatgcttt caaatgcgtc gtagcttttc gttcttaatt 2321941 tgatcgcacg cgttccctga atgactctgc cgtcaaacac aacataaacg ccgcccacgc 2322001 cttcacaggc aaatcgaatg gcatctgtaa tatttttttt ggcatcggtt ttttggaacg 2322061 tgatcggaat ctgcgagccg gtgatgacaa tcggcttttt ggcatgctgc agcatatacg 2322121 atagtgcggc agatgtatag gccattgtat ctgtaccgtg agtaataaca aacccgtcat 2322181 aggcatcata attttcctta acggcttctg ctatttccac ccagtattca ggctgcatat 2322241 tggtgctgtc tatattcata agcgactgag tttccattgt gtaatcgtta tcaagttttg 2322301 atacgtaact taataattca tcagccttga ctccgggagc cagcccattt tccccttcaa 2322361 ctgaagcaat cgttccccca gttgtcaaca tcaataattt tttcatacca tgcacctctt 2322421 cactgtatct aaagatgggt tgcgagaagg tattcgcttt tcgcatactt ttaatgcaat 2322481 tatagacacg gaaaataaaa tacgcaagac attattattc aattcgcgta cacttcctaa 2322541 tacctatatg atataatcag ctcaaggtga aaaaggagcg gaagttcatg aatctagatc 2322601 gtttaactga attgagaaaa aagaaaaatt ggtcgcttca atatacagct gaccttctcg 2322661 gtatcgcaaa aagcacatat gccggctacg agtcaggcta ccgacggcct tcacttgaag 2322721 cgcttgccat gctggctgac ctctttgaca caacctgcga tgaactttta ggccgcgaga 2322781 aacaaaagca gactgctcct caggccatag aattggccac gtggagcagc ctcgacttta 2322841 ccatttctgt tgatggccag ccgctgagtg aagatgaaat catccagctg attaccttta 2322901 tacgcacaaa aagaaaagta caggaggaac tgagttaatc tttagctcac ggtttaattt 2322961 taccgtaggt tcctcctcct ccggctttca attccagttt tccggatctc gcttttacga 2323021 taagcgccgc ggttttcggc gggacaacgc gagccaaatc ttcttctgca gcctcatgaa 2323081 gaacagccat ttctgttccg aaggcttttt ttagtttgtc cagcgttttc gggcctacac 2323141 ccggaacaaa ttgcagcggg atctgatgta catatcgcgg acgcgggacg cgaacttcaa 2323201 gctgatcact caattcacgc aatctatcgc tgactccctt ggtaaatctg gcttttccgc 2323261 aattcgcgca cgctgtttcc ccgcttacag caggctctcc gcacgcttcg caagccgtct 2323321 gataatattt ccccaataac gggtccaagc cataatttgc gataattttc ctgtcatctt 2323381 gtccctttaa tgcaagagca aattcagtaa aatcagctga ctgcacatat aattcattat 2323441 attctctgcc gattttcccc aacgaatgcg catcagaatt tgttaaaaaa ggatacggat 2323501 tcaattgcga tacgtgtgat gccatgtctg tatcacagct taatccaagc tccaccgcgt 2323561 ctatcataga tggatcaaaa acctcagtta agcttgattt aacccctttt ccatataagc 2323621 ttttatgcgg cgtaaagata tgggcgggga taaacaggcc gcccatatcc tgcacttttt 2323681 tttgcaggtt taagcccgtt tcataaatcc gctgcgagct taaatgaata tttttcagcc 2323741 gggctgacag ccagtttgaa aactgtttca tatcagccag cgtcggcata aatacgagca 2323801 catggatcgg tccgctgcag gcttcatcat aaatctccag ctcgctcccc aataaaagag 2323861 tcgtgctgcg ataacggatt cctcccccgt caagctcgcg atattttcca gatgaaatgc 2323921 cttcctcaag ctctagaatg acttccggag aatgacagtc gataatgccg aggagttcaa 2323981 ttcctttatg ttcactggct tcaaccaaaa ttctgtccag cgttaatgtt ttggcgcctg 2324041 ttattttgac agcccttcct gtaaaggtcc ggccgatatg aatgtgcaaa tccgcgtaaa 2324101 tctttttcat ttttgtgctt ggagcgcttc tttcagctga agatactgaa tcgcgtaggc 2324161 tgttttagca tcatatactt cacgcgattc aaccagcttt agcgcatctt caagcgtcac 2324221 ctccatcact tcaacaaact cgtcctcatc aagctcccgt ttttcttcaa gcacagaaag 2324281 ctcctcagca agaaaaacgt gaacgatttc atctgcaaat ccgggtgatg tataaaacgc 2324341 agttattttt gtcagttttt ttgctgtata accggtttcc tcttcaagtt cccgaagtgc 2324401 cgtatactcc ggctcctcac ctttttcaag cttaccggcc ggaatttcaa cgatcgtccg 2324461 ctcaagcggc ttacggaatt gtttgaccat gatgattttc ccttcatctg tgacggctag 2324521 taccgctaca gctccagggt gtttcacaat ttcacgttta ctggctttgc cgtttggcag 2324581 ctctacatcc tcgacataaa gatcaatgac tttacccgaa aaaatctgtt ctttggcaat 2324641 tgttttttct tctaatgatt tcatttcttc atctcccgtt ctgtctctat atgatgcccc 2324701 atacatttta tcatactaga gcaaaagggg gcttcttcgt gaaagtgcac cgcatgccaa 2324761 aaggtgttgt cttagtcgga aaagcatggg aaattcgagc gaagttaaaa gagtatggac 2324821 gcacatttca atatgtgaaa gattggatct caaagccata aaagttgaaa ctttagctcc 2324881 tttatattac ggtcaataca aagcctaaaa aaggagtgtg cacatgagaa agcgcaaatt 2324941 gggtacatct gatttagaca ttagcgaagt cggactcggc tgtatgtctc ttggaactga 2325001 aaaaaacaaa gcattgtcca ttctggatga agcgatcgag cttggcatca actatttgga 2325061 cacagcggat ttgtatgacc ggggacgcaa tgaagaaatt gtcggtgatg cgatccaaaa 2325121 cagacgccat gatattattc tggcaacaaa agcgggaaac cgttgggatg acggaagcga 2325181 gggctggtat tgggaccctt caaaagctta cataaaagag gcggtaaaaa agagccttac 2325241 acgtctgaaa acagattata tcgaccttta tcagctccac ggcggcacga tagaggacaa 2325301 cattgatgaa acgattgaag cgtttgagga attaaaacaa gaaggtgtca tccgctacta 2325361 cggcatttct tccatccgcc cgaatgtgat taaagaatat gtaaaaaaat caaacatcgt 2325421 cagcattatg atgcaattca gcctgtttga cagacgccct gaggaatggc tcccgctttt 2325481 agaggaacat caaatcagcg tagtcgccag aggtcctgtt gccaaagggc tcttaactga 2325541 aaaaccgctt gatcaagctt cagaaagtat gaaacaaaac gggtacttgt cctattcatt 2325601 cgaggaactg acaaatgccc gtaaggcaat ggaggaagtg gctcccgatc tttccatgac 2325661 agaaaagtcg ctgcagtatc tgctagcaca gccggctgtc gcttcagtga ttacaggcgc 2325721 cagtaagatt gagcagttac gggaaaatat tcaggcagca aatgcacggc gtttaaccga 2325781 agaggaaatc aaagcgctcc aatctcatac gaaacaagac atttacaaag ctcatcgctc 2325841 atagcagaaa aaccagcacc tgtacgggtg ctggtttatt tatattgatg ccaatccatt 2325901 tggctttcat ttaggagttc ttcaaagctc ttattttttt cgatctcttt tttctttcta 2325961 atctgttctg ctttttctct tttctgcctc ttttcatcct cttccttcaa ttggctcttc 2326021 atctccataa gctttgcttt gatatcggat tgaaggccgt cttttagctg gtgtttgtca 2326081 atggattttt gttttttcat gcagacttcc cccatgtttt gttttgaagc cagtttatca 2326141 cggagcatat aaactgaaca agcagactct cttctgatca ctttctcagc gtagcagtgt 2326201 ttaggtataa tgatcttaaa cacgaattgc ctatatattt cgttgaaagg tgctgtgact 2326261 tttgaagaaa atccttttgg ccattggcgc gctcgtaaca gctgtcatcg caatcggaat 2326321 tgttttttca catatgattc tattcatcaa gaaaaaaacg gatgaagaca ttatcaaaag 2326381 agagacagac aacggacatg atgtgtttga atcatttgaa caaatggaga aaaccgcttt 2326441 tgtgataccc tccgcttacg ggtacgacat aaaaggatac catgtcgcac cgcatgacac 2326501 accaaatacc atcatcatct gccacggggt gacgatgaat gtactgaatt ctcttaagta 2326561 tatgcattta tttctagatc tcggctggaa tgtgctcatt tatgaccatc gccggcatgg 2326621 ccaaagcggc ggaaagacga ccagctacgg gttttacgaa aaggatgatc tcaataaggt 2326681 tgtcagcttg ctcaaaaaca aaacaaatca tcgcggattg atcggaattc atggtgagtc 2326741 gatgggggcc gtgaccgccc tgctttatgc tggtgcacac tgcagcgatg gcgctgattt 2326801 ttatattgcc gattgtccgt tcgcatgttt tgatgaacag cttgcctatc ggctgagagc 2326861 ggaatacagg ctcccgtctt ggcccctgct tcctatcgcc gacttctttt tgaagctgag 2326921 gggaggctat cgcgcacgtg aagtatctcc gcttgctgtc attgataaaa ttgaaaagcc 2326981 ggtcctcttt attcacagta aggatgatga ctacattcct gtttcttcaa ccgagcggct 2327041 ttatgaaaag aaacgcggtc cgaaagcgct gtacattgcc gagaacggtg aacacgccat 2327101 gtcatatacc aaaaatcggc atacgtaccg aaaaacagtg caggagtttt tagacaacat 2327161 gaatgattca acagaataaa aaagcgaaag gcctcttcgg ctctttcgct tttttatgtt 2327221 acagaacgtc ggtaatgcca tccatatttt ctctgatcca ttcaatcgca agatctatcg 2327281 ttgtaaactc ctgcgtctcg aaggtcattt catcctgcaa tagccagaca tctttcttga 2327341 tggactctgc tcctccgatt gaccagtgaa gcaaggtata aggatggttt tgattcagga 2327401 aggataccca cgttttattt tgtgctgtgt tcttcattgc cttcagcttt tgttccacgt 2327461 ttcgcgtctc ctactttact aatatgctca ttctggggct gagcatttca gccgggcttt 2327521 tcagcgccaa tgttttggct ttttcattgt aatcgatcgt catttgatcg tcaaaaaaca 2327581 ctttttgcga cgattggata tacagcggaa tgccgttcgt ttccagctgc tcgcactgtc 2327641 ccgttaattc ttctgccagc cagattgtcg ggacaccgct taccgcgcag ccgcatcctt 2327701 ctgcatcgta acgaagctgg gctttttttc ccgggttggc gtcaaacgcc tgctgcagtg 2327761 cctgttttgc tgcatctgtc acatgtatgt tcataaggtg aaacccccgt tttcatcatt 2327821 ttcgctattg tagcatacaa tactgccatt cgcattgttt ctgccttttt tccaccgctt 2327881 cgcattttct tctgcagtct tgatccactc atctttccct tgtatatact gattgatgct 2327941 gtcagggtgc tgggccgcca gctgtttttt gagaacggcg tattctttcg ctatgtttgg 2328001 atgagctctg agataatctc tgaataacag atgcctttca atagcagggt ttccctgttc 2328061 gtacatatgg acatgatgag tgcgtttatt tccgcccttt tggaaataac gcctgcccgc 2328121 tataccgttc tcaccttttg gtgtatagcc gttggccttc atttgttcat caaattggct 2328181 cacggcttca atgcttctga cttcaattaa catatcaatg attggcttcg ctgccatgtt 2328241 aggtattgat gtgcttccga tgtgatgaat agcgataatc tccggcccga acacaagttt 2328301 cagccgttct ttttcttcat cgaaacattc tgcccatttt tcgttgtaga gaatgatctc 2328361 aacttttctt ttcggataca aatgaaagac cgacagcaat agaccctgcg ctgctttgac 2328421 ggtttctgcc ttttggaatc cggcctgtgt atagagtgac acagccgggg tattgttctc 2328481 ggctgtgact acttcgattt tctcagcgtc ttcattatga tcaatgacaa attgcagaag 2328541 cgctcgtcca attccttttc tgaaaccgtc aggatgcaca acaagcctgc aaatggtgag 2328601 ataatgcatg tttttctcat atgaaatgac accgatcagc ttgccgtttt tccgatatcc 2328661 cgcaaaccgt tcatgggatg cttgaatatc ctttaccttc tcttgtaaag cgggaatacc 2328721 gtcaaaaccg ataatctctg tttcctttat gtaggcgggg atctgtacgg ctaaaatctc 2328781 acgcgctata gtggcttcct tatgctggag aaattcaatc attcgtgttc tcctgaaaca 2328841 gccgctgtct gtcgactttt gcgacgcgga ctgcatacga ctcgtaccaa acgcttcttc 2328901 ctttttcttt tgctgcttga tgttcagtgt gatgcctcca atggttaatt gcgtccatac 2328961 tgtcccaata ggaaactgtg atgccccttc catccgcttc acgtacgctt tccacgccta 2329021 aaaatccagg ctgatccgcc gcaagtgata ccatccgctc cgctgtttct ccatatcctg 2329081 tgtcattttc gcttttgaca gaagaaaaaa tgactgcata gtaaggaggc tcaggtgttt 2329141 ttgataaaaa atccatcata tttccccctc atatgttttt gacaaatagt accctgtctt 2329201 ggcccgggcc atcatagttt gcaaacactg agatgccatt taccgttttg gtgccctttt 2329261 caatatcaaa ccccaatttt gtgtgatatg cgattgatac cttattcaca ggtgaagtga 2329321 cacacttcac ccgggtgcag cccctttgtt ttactgtttc gataaataca tcatacaatt 2329381 gtttcccaat ttgcattttt ctgaaatccg gatgcacacc ggaaaaatga atgtacgccg 2329441 tttcaggatc ggattgcgat tgaaatccga ttaaaaatcc cgtcatgctg ttatgttcgg 2329501 atgtaataaa gcttgtgtcc tgaaaatgct caaaaaatag tctcggcaat ttttctttca 2329561 gctgtctgcc gccccaccat tcattcagta cagacgttac catttcataa tctgaagacg 2329621 tgattgttcg aatatccatt acgatttgat ctccctccgt ctggcaaaac gaatgtcagc 2329681 tctttttctc acaatataaa aattatattt tgcctggctg gaattgtaaa tgccttcttt 2329741 cctgtatcat acgtttccag actgccgagg gaacaatgtt tgatcatttt acgcctattt 2329801 ctcccccaaa caggaggaga gactttacag cacaatatca agcacttgat caagtttcag 2329861 cttataaagc tgatcctcgt ctccttttat ccatactgct ttttcaaact cttcataccg 2329921 gcagattttc ccggtgcagc agacaatctc accgtcctga aagcagctga cagtgatatc 2329981 ctgagcaaac tccatcgcgg cgcaaagcgt ttgattcatc tcttccagct tatcggggtc 2330041 aaggatcggc ttttgcagct tctgtttaag tcgctttctc tccagcaggc tttgcttatg 2330101 ttccggcaga aacatcctgc tcccttccca cagcaggttg ccccttttta aatggtcgtt 2330161 catttataat gcccccctat tttagccgca cgttcaaatg cctggcctgc cgctgtcagt 2330221 gacgccgccc tgatgattgc tgtatcgccg aatcgatttt taatgccatc catcacatag 2330281 cctaggctca ttttctttgc ataatcctga aataaattga gctgccatat gtcatcagat 2330341 gagagctgag acagattgac accgaggcgg cggacgggtt tcccgtccca aaatgtaaga 2330401 aacagccgtc gtacagcctc atatacatcc tgcgtagaat tagtcggctc tgccagcttc 2330461 acttgccggt tgaagcccgt cggccaatca aaatcagcac cccggcagct cactgacact 2330521 gtctgcccca tgaccccggc gtttcggctt cgcctgcaca cctcttcact cagctcaagc 2330581 aatacgacct tgatttcttt gtcaaagtgt tcgtagtctc tcgggagagt cattccatga 2330641 cctatcgcct tttgcccgtc cagagacgaa gttgacacag gggaatagtc gattccgttt 2330701 gccgtcatcc acagcacgtg gccgttaatg ccccatttct tttttaaaag atcgagcgga 2330761 aaagccgcga gcccgccgat cgtgctgatg cccattcgat ttaaatgatg cttcatgcgg 2330821 ctcccgacgc caaacatgct gcccaccggg agcggccaca tttcggtttt catattttct 2330881 ttcgttaagg taaaaatacc gttcttattc tttttggcaa aattgtcaca cgcaattttg 2330941 gccagcgctt tgttagggcc gattccgacc cgtgcataaa cgccgatctc ccgcatgatt 2331001 ctgccctgaa tgcttttcgc gatctccatc ggcgtcccaa acagcttctg gctgcctgta 2331061 atgtccatga actgttcatc gatggaatac ggctccacaa ggtctgtata ctcctcgaga 2331121 atggccgtaa tttgcagtga tacatcaata taccgctgca tacgcggccg gagcacaaca 2331181 gcctcaggac acttttcctg cgcctcccac agccgtgaag cattcaccac acccttttgt 2331241 ttcgccagcg ggcaggcagc caatacgact ccgccccttt tttcagggtc acccgaaaca 2331301 atgacgggcc tatttttcaa atgtggattt tccgctttct ctacagatgc ataaaacgat 2331361 tgcatgtcaa cgagaaaaat cactttttct ttcatcatac acacctctaa aaagaactta 2331421 tgttcgcttt tcattatatg cgaaagtatg ttcgttttat actggtaaat gattcttgtc 2331481 tgacagaaaa tatgatccaa gggtttgaga gaagaaaaac atttagtaga ataaaagcga 2331541 agcataagga taggagagtc atgatggaga aatttgtcga aaaaatgctg ggacaggcat 2331601 tgcggcaata cggcagaaac gttgctatag atccgttaag cccgtatgaa aaacaaagcc 2331661 tgaaagcggc tctacaagag agacggaatg aagaaccaga tgaggatttg catgcgcata 2331721 tagaagatat catttatgac tatgtcacaa accaaggcct gttctcttaa acgcatgact 2331781 gtcagttctt tcagccgctg atgcggcttc cctttgaaaa caccgcctga aacaaataaa 2331841 cagtctcagg cttacagaaa aaaagcagga ttttctcacg ctccatagat tcatatggcc 2331901 tggcgtaaaa ttcccctcaa tgctcgcgca aaacggaata agctgtccat gatcacgcgt 2331961 atacactttt tcgaagagat gtgctctctt gttctgtcat gcggtccatg ccggttttca 2332021 gcgtacatct tgatctcata gccggtttca ctgccgatat gatccacgtt ctggcggctt 2332081 aaactaacac accctcactg accaatcgct ttgcttttca tcggacatcc cgtcattttc 2332141 cttctttcaa gatgtaaact ccgtcagcca cacgcatcct caacgcatag tatattgcca 2332201 tccatacaat caggcatact acatgtcaat aacgaaatat tttgaacgat ctattggaga 2332261 aggaaatttt ttcatatatg atagagaaag atcatacata caggagagaa tataattcat 2332321 gaagaaatgg aaagatatcc acccgatcag ctggacaatt ataatcggaa ccattttcgg 2332381 cagaatggca acatcgatga gcattccttt tttagcgatt tatttgacag ccgtccaagg 2332441 cgcatcagct tcctatgcag ggctggtcat cgccgcgagc tcatcagtcg gcatcctcgc 2332501 aagcttttac ggcggatata tctcagataa attcggcaga aaaaacatga tgcttgtatc 2332561 gattttcgga tggatgctgg tatttgcagg ctttgcggca gcatctaatc tctgggtgtt 2332621 ttttgtagta aacgcattaa acggtctttg caaatcactg tttgagcccg cttcaaaggc 2332681 cttgttgtct gatatgacag aagaaaaaac gagactgcta gtttttaatt tacgctatgc 2332741 ggctattaat atcggcgttg tcttcggacc tgtgcttggc ctatatttcg gctcatcgca 2332801 atcgactacg ccctttttgg tgcctgcagt catttacgga ctatacggaa ttgtgcttgc 2332861 cctccaattt aaaaaacatc catccttatc agcaccagcc cagtcccgaa atatgagcgt 2332921 gcgggaagcg tttatggtca cgcaaaagga ttatcttttt accattgctt tggtcggcat 2332981 tacgctatgc accttcggct actcacaatt cagttccaca ttccctcagt atatggcgca 2333041 gaaccccttg atcggcaatg gaacgaagct gtatgggctg atgctgacat taaacgcaat 2333101 cgttgtgttg gcgacgcaat ttcccattgt ccattttgca aaacggtttt cgccgctttg 2333161 ttctctgatg ctcggtaatg tgatggttag catcagcatg gccattttca ccgtatcaca 2333221 cggtgttcca tcaattgtga tgattgtcat cacatttaca atcggcgaag tgcttttatt 2333281 ctctatgatg gatttgtatg tagaccagat tgcaaaacca ggattaaaag gcacttattt 2333341 cggggcaatc ggtttttcac agctcggaaa cgtcatcggc ccttgggtcg gggggatatg 2333401 tatagacctg tttggcgctg gccggccgat ttatattttt tctgtcctga gcggcattac 2333461 cctgctcggc ctgccatttt tagcgttcgc ctatcggcaa atgaaaatgg agaccacaaa 2333521 acaccgttcc cgtctggaaa agccgcttta aataaaaaac ggaagagaat gaatctctcc 2333581 cgcaaacatg aggtgaagaa catgaatata ggtgatgtga tgtttcagct gtttgtattt 2333641 attatatttg ccgctgtcgt ctttgcggct gttacaggct tcaagtatgc gaaaaaccga 2333701 aaagcgcagc tggatcgcat tgagaaaaag ctgaacagcc tgtccgaaga tcacgattaa 2333761 cagcttgggg caacgagctc taccttaatc cggtctggat cctcacaaaa gactgcataa 2333821 tgcccgtctc ctccggcaaa aggatgcctg tctcggtaca acacacgata gccttttgcc 2333881 gtcaattttt cagtcatctg atcgacttga agcttggatt cagcatgaaa tgcgagatgg 2333941 ttcagaccga ctcggcatct atggtattcc ggctctagaa atggctcttt cgcctgcaca 2334001 atcactaggt aaaaacgatc tttcttccag ctgatgcctg agctccattt ttgatactct 2334061 ttataaccaa gttcttttaa gaaccagccc caaaaccgcc tagacgcctc caaatcagag 2334121 acatacagtt caatatgatg cacatttcat accctcctta ccaacacttc ctcgacctta 2334181 tgcccgtctc ccttacgcaa aatgagatct gacctgaatt tagttggcaa aatattttca 2334241 tataaattcg gccggttgac actctcccaa atcgaggctg ccatctcgtc agcctcctga 2334301 tcggacaagt ctttaaattt atgaaaatat gaatcaggat tttgaaaagc tgtttcccga 2334361 agcaggcgaa aacgctctaa ataccaagtg aaaatccggc tttcctccgc atccacataa 2334421 atcgaaaaat caaagaaatc ggaaacaaaa atacgcgggt tttcccggtc atcctccaag 2334481 gtgggcgact gaagaacatt aatgccttca ataatcacaa tatccgcctg ttctacaacc 2334541 tcgaacacac cttcctcgcg gtcataggtt agatgggaat acaccggggc ctttacgctg 2334601 tcctttcctg attttaagtc attcaaaaat tcgagcagcg cctttacatc atagctttca 2334661 ggaaatcctt ttcttgacat catatttttc tttttcagct cggcagtagg aaataaaaaa 2334721 ccatctgtcg tgataaggct cacttttgga cggtcaggca aacgcgaaag cagcttctgc 2334781 aagatccgcg ccgtcgtgct ttttccgact gcgacactgc cggcaatgcc gataataaac 2334841 ggaattttgg ctgaatgtgg gtgcttcaaa aaaacattga catgcttatt gcgttcagcc 2334901 gcagacttga catgtaaatg aagcaagcga acaagcggaa tatagatcgt ctccacttct 2334961 tcaacagata gataatcatt caatccttcc acagcttttg cctcttcttc agatacagca 2335021 atcgacaaat gccccccaaa accagaccaa gactcccgat tgtgctgtgt atataaagta 2335081 tgtaggttaa gttctttatt tttcactgtt tacacctgac tctctgtagg ttaaaaccct 2335141 tacaaagatt gtaacggaaa accttttcac tgtctgctta tttttcattt cgttttttta 2335201 gcaaatcagc accgattcgg ttatacgcag ccatttcatc ttttggaacc atgcttcctc 2335261 ccgttcccca gacgacatgt acggcatgtt ccatcttata tttctgagca tagcgccttc 2335321 cctcttctgt cgaaaaaagc tgaaccggcc cgaacatgcc agcaagagca gagggctcta 2335381 aatatttatc ttcagataca gccagcatat gaagcaaagt ataaagcgta ttgtcctcta 2335441 ccgtataaca gccgctcaga agcggttcaa tcagcttgcc gacaaatcct gacggcctcc 2335501 ctacggcaag tccgtcagca gccgtctgat tatccaggcc gatatcctgg acggagatct 2335561 tctcgtgaag tcctgaataa agccctaaca gcatacaagg tgaatgagtt ggttctgcga 2335621 aaaacacatg aacatcatct ccgtataaaa gcttcagccc aaatgctaca ccgcccggtc 2335681 ctccgccgac tccgcacggc agatacacaa acaagggcgt ctcaagactt ggctttatat 2335741 tcatacagtc aagctgtgtt tttaatcggc ttgcagcaac agcatatcct aagaacagct 2335801 gacgagaatg ttcatcatca ataaaataac agaatggatc ttgttccgcc tgccgtctcc 2335861 cttcgttcac cgcttcactg taatctgttt cgtactccat aacagtgact cccttttggc 2335921 ggaggagatc ctttttccac tgcttagcat cggcggacat atgcactgtc acgcgaaacc 2335981 cgagtgccgc gccgatgatg ccgatgctta aacctagatt tcctgtcgaa ccgacagcaa 2336041 tcgaatagcg ggagaaaaac ccggtaaacc gctcttcctg taagatgcgg taatcatcgg 2336101 tttcctgaag cattccttct tgaagcgcga gattttcagc atactttaac acttcataaa 2336161 tcccgcccct cgctttaatc gatcctgaaa tcggaagctc atggtcgcac tttaaaagcc 2336221 atcttccggg aaatggctgc tgatatgccg cttccagctt tcccttcata tgctgcacct 2336281 caaaaagcgg agactcgatg attcctttag cgcctttcgt ctcaggaaac acctcggcaa 2336341 tgtaaggtgc aaaccgctgc attctttttt ccgcttccgc tatctcggtt gcccactcat 2336401 ctgcacgggg taatggcccc tctttcttgc ctgaatttgc ccagaataca ggctctgcat 2336461 caatcagttt ctgaataaac ggatctttaa gcagagcatg aaggacttct gaatgaactg 2336521 acattcaaca atctctccct tccactatca aaaactgccc cgtgagaaac aagccactcc 2336581 accacaggca gttctatcat tattttttca tgagcgcgcg tcctgccagc ttttctacaa 2336641 gagctggaaa cagctgatac agcttagtgc cggcattcat taaacgcgga agattgatct 2336701 cccgcttttt cgtaaaaatt gcagctgtaa tttgagctgc cacgtcatca ggatcaagca 2336761 tccagcggcc gacatttttg gcgtagtccc cgcctttatc agcaatggaa aaaaagtccg 2336821 tctgaatcgg gcccgggttg actgttgtca cataaatgcc ggttcccgaa agctccatcc 2336881 gcaaagcgtt tgagtaacct aacacggcat gtttggtcgc ggaatacagg ctagacttcg 2336941 gtgtggcgat tttccccgct tgagaggcga tattgatgat atgtcccttt ttttgctcaa 2337001 gcatttgcgg aagcaccgct tttgtacagg cgatcaggcc gaagacattc acatcaaaca 2337061 tcgctttcat gtcatccaat gtagagtcta aaaccgtttc aaatataccg aagcctgcat 2337121 tgttaatcag tacatcaatc gagccgatct gatcgcggac ccgggcgata tcctctaggc 2337181 ggccgacatc cagaggaaaa atctcacact gtccgctcca ttcctcggtt attttccttt 2337241 tgatttctat caaacgatcc tcgcgtctag ccgacagcag gacatgggct ccttcagccg 2337301 cgcataagta tgcgattctt tctccaagcc ctcctgaagc gccggttatc caaatccttt 2337361 ttcccgctat atgtttcacc catttcacct cttcattgtt ttaaagtata cggtatttcc 2337421 ttcccaatat gacgtgatgg cttcttcagc ctccaacaca tcaaggtgac ctgccgtttc 2337481 tgacatcgtt aaaaacaatt ccttttcata tacagcagga aaaagctgct gacagacctg 2337541 aaaagcggtc atcggctttt catccagcat gcgacgcaca tcctccgtcc tgttcctctg 2337601 cttgtcaaaa cgcttctcaa tcagcgcttg tacactggtg ataggctcgc cgtgaccagg 2337661 aaatacgatt gttggatcaa gttgagacag ccttcgcaat gaccgctgat aatccactaa 2337721 aggctttgac ctgacgtctc ccgctttcgg cgcttccaaa atcggattag acgagctgtt 2337781 tgccagcagt agatcgccgc caagcatcct tccgcttttt tcatggaaca gaacaatatg 2337841 cgattcagca tgtccaggca tctccaacac agaccagccc tcaagcccat ctatgcccat 2337901 accttctctg attgattttg tcagagatct cgtacaggaa aatgcgtacg ctgatcgaat 2337961 cagcttttcc gccttccccg tatcaaatgg aacgcctaat tcaggcagca gcttttgaaa 2338021 aaaacgtttt tgccaatcca taaaggcttg attttggctg atataaggtt cgttgaatgt 2338081 atgcccaatc acttcgattt catctgaaaa gacatcaagc aagcctgcat gatcagcatg 2338141 atggtgagtc agtacaacct gctcgatatc tgacaatttc acatttacag cggcaagctg 2338201 ctcttgtaag gctctggcag cctcttttgt attcggcccg gcatcgataa gtgtcagcgc 2338261 atcacctttt acgaggtaaa cgataacatc gccgacagca aacggtgtcg ggacgcggat 2338321 cgcaattaca tcttcagttg tcatcctttc gctccttgtc ttcattcatt attcatattt 2338381 tagctttttc tcggtcttgt gtcattattg cagaatgaga acaaaccttt ttgaaaaagc 2338441 tattgacatt agcttgtccg ccattgcata atgaacaaca aactaaaacg agaaccattg 2338501 gaacgctatg acgaggaata gtatacaagg caatggccta agagagcgat acccccggct 2338561 gaaaggtgtt gcggcccgct tgtttgtaga acctgccctc aagtcgcggt taggaaaacc 2338621 taaacgtttc ccgcgttacg gggatttgag ctgagcacaa tttgtgctaa tgagggtggt 2338681 accgcgaacc ttttcgtcct ttacgtgatg aaaaggtttt ttgttgttct aatagaagga 2338741 ggatatcaat gaaaaagata ggatttgtcg gcgccgggtc aatggcagaa gcaatgatca 2338801 acggcatttt gcaaagcggc atcacaaaac cagaacatat ctatattaca aatcgctcaa 2338861 atgacgagcg tctgattgaa ttaaaggaaa cgtacagcgt gcgtccatgc agagataaaa 2338921 atgagttttt cactcacacc gatatcatta tcctcgcttt caaaccgaaa gacgcggcgg 2338981 aaagcatcga cagcatccgg ccgtatatca aggaccagct tgtcatttca gtacttgcag 2339041 gccttaccat cgaaaccatt cagcattatt ttggcagaaa gctcgcggtc attcgcgtca 2339101 tgcctaatac atcagcggca atcagaaaat cagcaaccgg attttccgta agcacggaag 2339161 caagcaagaa tgatattatt gccgcaaaag ctctattgga aacaatcggt gatgcaacac 2339221 tggttgagga gcggcatctt gacgctgtca ctgcaatcgc aggcagcggc ccggcctatg 2339281 tgtatcgtta tattgaggcg atggaaaaag cagcacaaaa agtaggatta gataaagaaa 2339341 cggcaaaagc actcattttg cagacaatgg caggggcaac agatatgctc ctccaaagcg 2339401 gcaaacagcc ggaaaagctg cgtaaagaaa tcaccagtcc tgggggcact acagaggcag 2339461 gtcttcgcgc tttacaggac tcccgctttg aagaagcaat tattcactgt attgaagaaa 2339521 cagctaaacg gagcgcagaa atcaaagaac agtttgccgg tgccgcctta gagagacatt 2339581 cttagatgta aggacaaaaa cagaaggcac agtgccttct gttttttatt tttcccgcag 2339641 cagctggccg gcagattctg attgctttaa tagcgcggag atcgtaaatg aaagcaaatc 2339701 gggaagcact tcaaaggaat aaggcatata caatctttcc gtccatttat gcgggtcttt 2339761 accagccgga ccgacattta aaactgggac atataaagcc tgatttttac cgcttggcaa 2339821 tgaataccct ctgttaaaga gcggcatatt gcttgtgtat gcatcaacct cctgtttttc 2339881 cagctgaaga taactcaagt ccgaaagtcc ggggaagtac tgaacctccc gtaatgcaat 2339941 gccgtatcgc tcagccgcat aatgctttat ctgatctgct gtatttctga tcaattgatc 2340001 atcctttgaa gaaacagctg gataaagcgg cggactataa aacagaacga tgagcggcgc 2340061 atcctcctta caaagcgaag caagctcaga aacaattttc gtcgaaaaat ccctgtctcc 2340121 aagctccccc ctgttagcaa aggcataatt tagagcccgc tctgtttccg agatccccgc 2340181 acgctttttt gcacgcgaga ccagctcatc aaatgtcaaa acagtgacgt cccgctcaat 2340241 cggctgaaat ggctcaaatt gttgaaaatc ctgtgttttc ttccgaacgt tcgacatgat 2340301 ttcctccgcc gcctgttctg ctgttttaag cagcatctga tgcagctcac tagctgagcg 2340361 tttcattgac agcacattaa ataatgtgac ggctgtatgc ggtgtctgga ctgaatatgc 2340421 ctctttcaag tccttttgca ttaagtttac cggcggcgga gtgacctcgc catcaacctt 2340481 ttcgcaataa tcagcattca gttcaagcaa acggttaatc tcagatacca ttaaatttgc 2340541 gtttagacct gaaaacggct ctccaacatg tgtctcaatc cccttgcaga aaaaacccgc 2340601 aagcaccttg ccaatgcttc ctgtataaaa atattgctgc tgatcgccgg gaaatttttc 2340661 aaacatcggt tcggcattca ggcaagcggt taatgtgata tcatgctttt tctccatctc 2340721 cttcaatgca ggaaccgctt caatcatgcc tcttgaattc acttcctcgt ccggaaccgt 2340781 tatcaacagc agattgccct caaaatgccc gttcattgcc ctctccagca tcgacagttg 2340841 aatacaaagc cccgctttca tatccatcgt ccctcttccg aacagccagt ctccgctttc 2340901 ggcatctctt ctcacacgtt ccgggagcag ctcttttttc tctaaaaagg agctcaaaag 2340961 ctcagcaggc ttgcaagcca tatgtttaaa ttcgccgtaa tcttctatgt caacgacatc 2341021 aaaatgactc agcagaagca ctgtcttttt gacattcttc tttttgacta gagccgtaag 2341081 aaaagatctg ccatcgtcca tcggatgaag tgttacatca tcagggtgct tttgaaaata 2341141 gggcttgtcc ttcaaaataa aataaagata ctctgcaagc gctacctcgc cctttgaacc 2341201 ggtgatgctt tcgtattgca caagagaagt taaaagtgcc agcaattcgt ccttcgtctg 2341261 ccaattcatt gattccgccc ctcctatgaa taaaaatgct tctatactga aaaataaact 2341321 gatttctcgt ctattataca gaaatgtttg acaaaagcgg ttcatttgag cagtttatat 2341381 gacgggaaag aaatgacttg atataatcaa tctctaaaaa ccttacggga ggcgaaagaa 2341441 atggccagaa aattatttac acctattaca attaaagata tgacgttaaa aaaccgcatt 2341501 gtcatgtcgc caatgtgcat gtattcttct catgaaaagg acggaaaatt aacaccgttc 2341561 cacatggcac attacatatc gcgcgcaatc ggccaggtcg gactgattat tgtagaggcg 2341621 tcagcggtta accctcaagg acgaatcact gaccaagact taggcatttg gagcgacgag 2341681 catattgaag gctttgcaaa actgactgag caggtcaaag aacaaggttc aaaaatcggc 2341741 attcagcttg cccatgccgg acgtaaagct gagcttgaag gagatatctt cgctccatcg 2341801 gcgattgcgt ttgacgaaca atcagcaaca cctgtagaaa tgtcagcaga aaaagtaaaa 2341861 gaaacggtcc aggagttcaa gcaagcggct gcccgcgcaa aagaagccgg ctttgatgtg 2341921 attgaaattc atgcggcgca cggatattta attcatgaat ttttgtctcc gctttccaac 2341981 catcgaacag atgaatatgg cggctcacct gaaaaccgct atcgtttctt gagagagatc 2342041 attgatgaag tcaaacaagt atgggacggt cctttatttg tccgtgtatc tgcttctgac 2342101 tacactgata aaggcttaga cattgccgat cacatcggtt ttgcaaaatg gatgaaggag 2342161 cagggtgttg acttaattga ctgcagctca ggcgcccttg ttcacgcaga cattaacgta 2342221 ttccctggct atcaggtcag cttcgctgag aaaatccgtg aacaggcgga catggctact 2342281 ggtgccgtcg gcatgattac agacggttca atggctgaag aaattctgca aaacggacgt 2342341 gccgacctca tctttatcgg cagagagctt ttgcgggatc cattttttgc aagaactgct 2342401 gcgaaacagc tcaatacaga gattccggcc cctgttcaat acgaaagagg ctggtaatgc 2342461 ccataagaga tatcctgtag aggatatctc tttttttatt tttagagaaa cgatcggcta 2342521 aggttctccg tctccctagt agaaccaatt agaggagatg actccaatga aatcagcttg 2342581 gatggaaaag acatatacaa ttgacggatg tgcgtttcat acacagcacc ggaaaggatc 2342641 aagcggtgta acgattgtct ttgaggccgg ctatggtact tcttctgaga cgtggaaacc 2342701 attaatggcg gacattgatg atgaatttgg cattttcaca tatgatcggg caggcatagg 2342761 aaaaagcggg caaagcagag ctaaacgaac agctgatcaa caagtgaaag aattggagag 2342821 tttgcttaaa gcagctgatg taaaacctcc ttatttggct gtttcacact catacggagc 2342881 tgtcatcacc ggtttatggg cctgcaaaaa caagcatgat attatcggca tggtccttct 2342941 tgacccagct ttaggcgatt gcgccagctt tacctttata cccgaagaaa tgcacaaatc 2343001 acatacgaga aagatgatgc ttgagggcac acatgcagag ttttcaaaaa gtctgcagga 2343061 gctcaaaaag cggcaagtcc acttaggaaa catgcctctt cttgtgttgt catcaggaga 2343121 acggactgag aaattcgctg ctgaacagga gtggcaaaac ttgcacagca gcatattgtc 2343181 tctatctaac caaagcggct ggattcaagc taaaaacagc tcccacaaca tccatcatga 2343241 tgaacctcat atcgttcact tggctattta tgacgtatgg tgcgcagcgt gccagcaggc 2343301 cgctcctctt taccaggcag tcaattaacg taaaaaaaga ccgggccgta agggattccc 2343361 ggtcttttat attattttgt ttcacggtga agggtatatt tctttaaacg cggtgaatat 2343421 tttttcagct ccaaacggtc tggattggtg cgtttatttt ttgttgtgat gtaatttcgg 2343481 tctcccgttt cagtgcaaag ctaaagtaac atttactctc ataattaaca tctccttata 2343541 aaacgtaatg attacgtttt attatacaac gtcatcacaa attgtcaaat aagagctccg 2343601 ccttcagcct cgcgggacgt ttacctctaa gaaatcatat gccgccacgc tattggggaa 2343661 aacgtcaacc gcttcttttt gaagctccaa agaagcatct ccctgatatc ttgcgctgat 2343721 atgggttaaa atgagctgct tcgctcttgc ttctttcgct gttacagccg cttgttccgt 2343781 tgtactgtga taataatcat aagcaagttt acggtcttcc ttagcaaagg ttgcttcatg 2343841 aacaagcaca tcacaatccc tcgcaagctc ttttagtttg tcacttactc tcgtatcacc 2343901 ggagaacaca acagatcttc cctttttagg aggctccaga aaatcattcc cattgatgat 2343961 tcgtccgtct tcaagcgtta ccgtttcgcc ttttttgatt ttctgatata caggtccggg 2344021 cgggatgttc atttctttta atacgtcagc cttcaaggaa cccggtacgt ctttttcctg 2344081 cacacggtac ccgaaggctt ccactccatg aataacagat accgctgtga caataaactg 2344141 atcgtcctca aacacgattc cttcttcaat ttcctggatc gcaagcggat atgtcaaatg 2344201 ggttttcgtg acggcaaggc ttgtttcaat aaacgccttg atccctttag gtccgtacac 2344261 tgtcagctcg tcctctccgc cttgaaagga acggctcccc agaagccccg gaagtccgta 2344321 tacatgatcg ccgtgcatgt gtgtaataaa gattttctct attttacgag gtttaatcgt 2344381 tgtatgtaaa atttgatgct gtgtggcttc cccgcagtca aaaagccata ccgaacgcct 2344441 ttcttcaagc aattttaatg ccaccgacgt tacatttctc gccttggcgg ggatgccggc 2344501 tcccgtccct aaaaaaagta attccacgtt tccttcctcc tactagaacc agatacctac 2344561 aagaatacag gatcaagcgg aaaatgtgaa tcttgcctct gaaaagaaca atcctttcgt 2344621 gctagaaaca ttttttcagc attctgctta aaaaagggct taaatgtttg ctttcgttga 2344681 attttagatt taaaatgaag gaaatatacg gggtgtacta aaataaagct tcgaataaag 2344741 tgaggtactt ttagtgaaaa caaaccaaca accaaaagca gtaattgtca tattcggtgc 2344801 aactggagat ttagcaaaac gaaaattgta tccgtctatt caccgtttat atcaaaacgg 2344861 acaaatcgga gaagagtttg cagtggtagg agttggaaga agaccttggt ctaatgagga 2344921 tcttcgccaa actgttaaaa catccatttc ctcatctgca gataagcata tagatgattt 2344981 cacgtctcat ttttactatc acccgtttga cgtgacaaac cctggttctt atcaagagct 2345041 aaacgtattg cttaaccagc tggaagatac atatcaaatt cctaacaaca gaatgttcta 2345101 cttggcaatg gctcctgaat tcttcggaac gattgcaaaa acattaaaat cagagggtgt 2345161 aacagctaca accggctggt cccgccttgt catcgaaaaa ccgttcggcc atgatctgcc 2345221 aagcgcacag gcattgaata aagaaatccg cgaagcattt acggaagatc aaatttacag 2345281 aatcgaccat tatctaggca aacaaatggt tcagaacatt gaagtgattc gatttgccaa 2345341 tgcgattttc gaaccgcttt ggacaaaccg ctacatttca aacattcaaa tcacatctag 2345401 cgaatcacta ggcgttgaag accgcgcaag atattacgaa aaatcaggcg cccttcgcga 2345461 catggtgcaa aaccatatta tgcagatggt tgcccttctt gcaatggagc cgcctatcaa 2345521 attgaacaca gaagaaatcc gcagcgagaa agtgaaggtg ctgagagcac tgcgtcctat 2345581 tgcaaaagac gaagtggatg aatactttgt gcgcggacaa tatcatgctg gtgaaattga 2345641 cggtgtaccg gttcctgctt atacagatga agataatgtc gctcctgact ccaatacaga 2345701 aacctttgtt gccggcaagc tcttgatcga caacttcaga tgggctggtg ttccattcta 2345761 catcagaacc ggaaaacgaa tgaaagaaaa gtccacaaaa attgtcgttc aatttaagga 2345821 cattccgatg aacctgtact acggtaatga aaacaacatg aatccgaact tgcttgtcat 2345881 tcatattcag cctgacgaag gcattacgct ttacttaaat gctaaaaagc ttggcggagc 2345941 agcacacgca cagccaatca aactcgatta ttgcagcaat tgcaatgacg agttgaacac 2346001 ccctgaagca tatgaaaaac taattcacga ctgtcttctt ggcgatgcaa caaactttgc 2346061 acactgggat gaagttgccc tttcttggag ctttgtcgac tctatttctg aaacatgggc 2346121 agcaaacaaa accttatctc ctaactacga atcaggctca atgggaccga aagaatctga 2346181 tgatcttttg gtgaaagacg gcttacactg gtggaacata taataagaag aaaaaagccg 2346241 aaatagttta ctaagcattt tcggtctttt ttacgctgaa caaaggtata acaatctcct 2346301 taataacaaa acccccaaag cttaagagct tcgggggttt ctattgatta cttcatccat 2346361 tcagtatgga agatgccttc tttgtcagta cgctcataag tatgagcgcc aaagtagtcg 2346421 cgctgtgctt ggattaagtt tgcaggcagt acggctgtgc ggtagctgtc atagtaggct 2346481 aatgcgcttg agaatgatgg caccggcaca ccttgggcaa ctgcaagtga aatcacttgg 2346541 cgaagcgctc cttgatagct ttctacaata ttcttgaaat agctgtcaag aagcaggttg 2346601 tcaagctcag gctcgcgatc gtaagcttct ttgatcttct gaaggaatgc cgcgcgaatg 2346661 atgcaaccac cgcggaagat catagcgatt tcaccatatt tcagatccca gttgtattct 2346721 tcagaagcag ctttcatttg ggcaaatcct tgcgcgtatg aacagatttt actcatgaac 2346781 aacgcttttc tgaccgcttc aatcagctct tctttatttt ctgtaacagg cttcacttct 2346841 ggtcctgaaa gaagtccgct cgcttttaca cgctcttcct tcatagctga gataaagcgt 2346901 gcgaatacag attcagtaat aatcggaagc ggaacgccta agtcaagtgc gctttggctt 2346961 gtccattttc ctgttccttt ttggcctgct ttatcaagaa tcacatcaac aagcggtttg 2347021 cctgtttctt cgtctttttt tgtgaagatg tcagccgtaa tctcaatcag gtagctatca 2347081 agctcacctt tattccattc agcgaaaact tcatgaagct catcagcaga aaggcccagc 2347141 acctgtttca gaatgaaata tgattcagag atcagctgca tatctccgta ttcaattccg 2347201 ttgtgcacca tttttacgta atggccggcg ccgtccggac cgatatatgt cgtacaaggt 2347261 tctccgtcaa cttttgcaga aatggcttca agaatcggtt ttacaagctc atgtgcttct 2347321 ttttgtccgc caggcatgat agaaggtcct ttaagcgctc cttcttctcc gccggaaacg 2347381 cctgttccga taaaatgaat gccgctttca gcgagttctt tgttacggcg ctgtgtatct 2347441 ttatagtatg tattaccgcc gtcaattaaa atatcatcct tctctagatg aggaagaaga 2347501 gattgaattg tcgcatctgt tgcagttccc gctttaacca ttaataagat tttgcgcggt 2347561 gtttccaagg attggacaaa ttcttcaatg ctgtaagtgc caacaacatt ttttcctttt 2347621 gcctcctgta aaaactcctc agttttactg cttgatctgt tgtaaacaga aacagaaaat 2347681 ccccggcttt cgatatttaa agccagattt ttacccatga ccgcaagtcc gataacgccg 2347741 atttgttgtt ttgacatatt ctaacgtccc ttctgcaaac gtttaatcat tttaaaattt 2347801 aaattaaaat aaaatgatat ttataataaa gaaattacca tacattcacc ctttttttca 2347861 agcgattcag cttttctttt catcttgaaa aaaatcttta ttaaagcttg ttccctttgt 2347921 tttgctctcc tcttttttta acgttgcccc ttttctgatc agtttggtac cgtacttttt 2347981 attcagcttt tccatcatct gctgaatggg ctcatccttc gcatcttcat taaagctgaa 2348041 caaatcgagc tgtttatagg cctgctcttt ttctactaaa tccgttccgg taatgccaag 2348101 cagcctgaca ggatttttat tccaatgttt aaaaaagagg tgctccgctt ctttcaaaat 2348161 gtcatttttt tgatcaatcg ggtttctcag cgtagtgctt cttgtgatgg ttctccaatc 2348221 cgcatatcta atcataataa aaagcttcga agccatgact tccttgcgct gtaaacggtc 2348281 actcacagaa gcggcaagct ttctaaaaac gcctaacagc tcttcttcat cactggaatc 2348341 atgggaaagt gtcgatgagt tgccgacgct tttaaattcg taaatgcgct ccgggtcaac 2348401 cggcgcatgg tgaatgccat ttgctttatt tttaaggcgc ggaccgttga tgccaagcag 2348461 gcgcttcagc gagtgttcat cagctgcagc tagctctccg attgtatgga tgccgagtcc 2348521 cttcagtttt tccgctgtct ttttgccgac tccgtgcatc tctccaacag gaagcggcca 2348581 caggatatcg ggcacttgcc tctttcttaa gatcgtaatt ccaagcggtt ttttcatatc 2348641 agacgccatc ttagcgagaa atttattcgg tgcaatccct atgcttgacg ggagcagcag 2348701 ctctttttgc agcctgcttt ggatttcttt tgccgtctct agagcgcggc tgctgtatgg 2348761 tgtatcggtc atgtccatat agccttcgtc gatggagaca ggctccacta ggtcagtata 2348821 ttcacgaaga atggtaaaca tcgctcgtga agagtttcta tagcggtcaa agttcggcgg 2348881 aagaacgatg agctcaggac aatggcgctt cgcttgccaa accggcatcg ttgttttgac 2348941 gccgcgcgct cttgcttcgt agctgcatgt taccacaatg ccctttcgct cctttacgtt 2349001 tccggcaact gcgaccggct ttccccggag agccggatca tatgccattt caaccgacgc 2349061 ataaaagcta ttcatatcaa tatggaaaat aattcggctc tttcccggca taaacaaatc 2349121 tccttttcgg tcattagaca acagcttgta catatagtaa aatgaagcta ttgaatggat 2349181 gtgatgacaa tgtttgtgga atcgataaat gacgttttat tcttagtcga ttttttcaca 2349241 attattcttc ctgctctaac ggcaatcggg attgcattcc tcttacggga gtgccgtgcg 2349301 ggcgagcaat ggaaatcaaa acgaacagat gaacatcaga cggtctttca cattaaccga 2349361 acagactttc ttattattat atatcatcgc attacaactt ggatacgtaa agtcttccgc 2349421 atgaattcgc ctgtgaacga tgaggaagac gccggttctc ttcttttata aaccgcattt 2349481 ataaaaagga ggagaacaaa attgttaaaa acatatcaaa aacttttggc tatgggtatc 2349541 tttttgatcg tattatgctc gggcaatgct gcatttgcag cgactaatca ggtgggaggc 2349601 ctcagcaacg taggtttttt ccacgattat ttaatcgaac cgttttccgc tctgcttaag 2349661 ggtgttgccg ggctgtttca cggagaatac ggactctcta ttatcctcgt aaccattatt 2349721 gtgcgtatag ttgtattgcc tttgtttgtc aatcagttca aaaaacagcg catcttccaa 2349781 gagaaaatgg ccgttattaa acctcaggtt gacagtatcc aggttaagtt gaaaaagacg 2349841 aaggacccgg aaaagcaaaa agagctgcaa atggaaatga tgaagctgta tcaggagcat 2349901 aatatcaacc cgcttgcgat gggctgtctt ccaatgctga ttcagtctcc gattatgatt 2349961 gggctttatt acgcgattcg ctcaacacct gaaattgcgt cacactcgtt tctatggttc 2350021 agtttagggc aatctgatat tctcatgtcc cttagtgcag ggattatgta ttttgtccaa 2350081 gcctatatcg ctcaaaaact gagcgcgaaa tattccgctg tcccgcaaaa ccctgcagcg 2350141 cagcaatccg caaaattgat ggtgttcatc ttccctgtga tgatgacgat tttctcgctt 2350201 aatgtgccgg cagcccttcc gctgtactgg tttacaagcg gactgttttt gacagtgcaa 2350261 aacatcgtcc ttcagatgac gcatcataaa agtaaaaaaa cagccgctct tactgagtcg 2350321 gtgaaataaa aaagcaaccc cgtgcaaaaa gccggggttg ttttttgtta cttgcaaagt 2350381 accgcgccaa acagtcttgt ttatcatggc tgaagcagaa atggccatcc taaaaaatag 2350441 ccgtatcgtt taaaaagaag gaaatcggga atacctttac tcacctccaa ccgaaaggag 2350501 cctatacgtt gacggaacgc tttcagcaaa aaaatatttc tgtacctgat ggaatctgga 2350561 tcatgagaca aacctggaat gatgtcttat ttgctcactg gcctgttgat gtttctatcc 2350621 ttcgcgcttt ggtaccgtcc gttttagaat tagatacata taacgggcaa gcttggatca 2350681 gcatgcttcc ctttatgctc acgaacctga gggcgcgtta tctccctgtc attcccggtg 2350741 cgcgtgcatt tcctgagctt aacctccgca cctatgtcac gtataaaggc aagcccggca 2350801 tttatttttt tagcttagat gccgatcatc gtctggcggt ccttggcgct cgcacattct 2350861 ttcatctgcc ttatttttac gcggatatga agtccgaaaa aaacggtgat gccattgact 2350921 atgtcagcaa gcggaaaaat gacaaagaag cagcattcca cgccgcatac cggccaattt 2350981 cagcgccttt tacagcagaa aaggattcgc tcgattactg gctgacagaa cgatacaggc 2351041 tctacaccac ttatcgcaat aagctctatt acgaagacat ccatcatcat ccgtggctgc 2351101 tgcaaaacgc cgaagcagaa atttcagtca atacggtgac tgatgctcac ggtattacat 2351161 tgccggagtc agaccccttg cttcattatg ctaaaaaaca ggatgtgtta ttttggccgc 2351221 ttaggaaatg gagctaaaaa aacccgatgc gggaaatcgc actcgggttt tcttttttta 2351281 ttttgccgcc tcttcaataa tggcaacaac catttctgcc gttttaacga gctcttcgat 2351341 cggcattttt tcattttttg tatggatttg ctcataaccg acagcaagat tgaccgtcgg 2351401 gatgccatga ccagcgatta cgttcgcgtc gcttccgccg ccgctcgttt gcagctcgct 2351461 tggacgtccg attttagcag ccgctttttt cgcgatttca acaacttggt cgccgtcttg 2351521 atatttaaag cccggataca taacctcaat ttcgacttct gcgcgtccgc ccatatcagc 2351581 agctgcctct tcaaaagcag ctttcatttt ttgaacctga gcttccattt tctcaggaac 2351641 taaagagcgc gcttcagcaa gaatatgaac ttcgtcgcac acaatgtttg tttgtgtgcc 2351701 gccttcaaac cggccgatat tagctgttgt ttcttcatcg atacggccca atggcatttt 2351761 tgagatggct ttgctagcga ttgtaatcgc tgaaatgcct ttttcaggtt caaccccggc 2351821 gtgagcggtt ttcccgaaaa ttgccgctct taccttcgcc tgtgtcggcg cggccacaat 2351881 gatatttccg acttttccgt ctgaatcaag agcatagccg taggatgcag tgatcataga 2351941 acggtcaagc gccttcgctc cgatcagacc cgattcttcc cctactgtga tgatgaattc 2352001 aatcgtgccg tgttcaatat tttcttcttt cagcacctta atcgcctcaa acattgcagc 2352061 caatcccgct ttatcatcag cacctaaaat cgtcgtgccg tcagttttga cgtaaccgtt 2352121 ctctacaact ggttttacgc cgtttccggg tacaactgtg tccatatgag atgtaaaata 2352181 gatcgtatct gtttgttttg tcccttttag cgtgcaaatc aggttaccgg ctccgtggcc 2352241 cgtgatatcc attgtatcgt cttctttaac gtccacacct aaatcagaaa attttcgttt 2352301 cagcactttg cagatttcag cttcgtgctt tgtttctgag tcaatttgga caagctctaa 2352361 aaattcttcc agcaggcgtt tttcattcac catttgtaag tccctccata ttaaagcggt 2352421 atgttaccgt gctttttttt cggtctctct tctgtcttat gtgtaagcat atgaaaagct 2352481 tgaatcagtc ttccccttga ttcttccggc aaaatgatgt catcgaccat tccacaagcg 2352541 gccgctttgt atgggccggc gttttgcttt ttgtattcag cagttttttc gcgtttcgtc 2352601 ttttgcgggt cagctgaagc tttgatttcc ttttcataca aaatcgatgc cgcaccttct 2352661 ggacccatca ctgcgatttc agcattcggc catgcaaaca caaggtccgc tccgatcgct 2352721 ttgctgttca tggccacata ggcgccgccg tacgcttttc taatgatgag tgtgactttt 2352781 gggacagtcg cttcagcata agcaaacaat aattttgctc catgcctgat gattccgttg 2352841 tgctcttgct gaatacccgg cagaaacccc gggacatctt cgacagtcaa cagcgggata 2352901 tcaaatgcgt cacaaaaacg gatgaacctt gctgctttat cagcagcgtc aatcgtcagg 2352961 cttcccgcca gatgcttcgg ctggctcgcc acgatgccga ttgctttttc acccagcctt 2353021 gcaaacccaa tgacaatgtt cttcgcaaaa aatggctgaa tctcaaaaaa agactgcggg 2353081 tcagccagct ccctaatcac cttccgaaca tcataaggct ttgtcgtatc agcagggaca 2353141 agacggttta ataacggtct ggacgcctct ttctctggct tcggctctgt tgtccggcca 2353201 ttcagcggca aataagacag tagttttctc acccctgtca gaacctcctt ctccgtatgc 2353261 ccggaaaagt gggcgtttcc gctgacggca ttatgtatcc ccgctccgcc taagctctcc 2353321 gcatcaacct gttcccctgt cactttttca atcaccttcg ggccggtaat aaacatccgg 2353381 ccagtctgtt cagccataaa tataaaatct gtgagtgccg gagaatatac agcgcctcca 2353441 gcgcacggcc ctaaaataac cgatatttgc ggaatgactc cggaatataa gacgtttcgg 2353501 taaaatatgt gaccgtatcc atctaatgat aacacaccct cttgaattct cgcaccacct 2353561 gagtcattca gcccgataat cggcgcctta ttttttgctg ccagatccat caaagcgcag 2353621 attttcctgg catgggtttc gccaagcgcc cctccgtaca ctgtgaagtc ttgcgcaaat 2353681 acataaactg agcgaccgtc aattgtgccg taccctgtca cgaccccatc ccctaacatg 2353741 cgctgttctc ttgttaacac ttgactttcc atgaaggggt gtaattcgat aaagctgtcc 2353801 tgatctagaa gaaatatgat cctttcccga gcagtgagct tgcccttttg ccgctgctga 2353861 gccagctttt cccgtcctcc gccttcttct gcctgcttgc gtttcgtgta aaaatgatcc 2353921 atgtgctcat tcatgctcat tgtgttggtc tcctttcggt tcacaaagct ctacaagaac 2353981 accgtttgtt tcccgagggg aaataaacgc gatctttttc ccgttcgctc cctgtcttgg 2354041 aaacctgtca atcaattgaa catgctgatc agacaatgct tgaagctgtt cagataggca 2354101 gttgcacaaa aacgcaatat gatgcagtcc ctgccctttc ttctccaaaa ataaatggac 2354161 ggggctgtca gctgtcaacg gctctatcag ctcaagtttg acgctaccag cttgaaaaaa 2354221 agcaacattc accttttgct cttcaaccgt ttcttgatga agaaatgcaa gccccaatac 2354281 attttcataa aagcttcttg catcttttat cgaaaaaacg gctatcccga tatggtcaag 2354341 cctgttcatt ttcatccctg ctttcgctaa tagatatcgc ttgtccgccc attcaaaaca 2354401 cgctaaaata tagacagatt gtttaaggag tgaaaatcat gtctcaaaaa ctgatgaaaa 2354461 gcgttttgat cgtgattttg ggagttttta ttctttcaac tgtactctca ggaatcgtca 2354521 tgtttctata acgataaaaa agcaggcgcc ttattcaatg ggaatatcct gcttttttat 2354581 cagagcttta tgctcgatgg caatctcctc aaaagagcgg ttgtcgtccg tgatcagcac 2354641 tctcgttcct actggtatcg tttgaaacaa atgaacaacc tcatcgttat gcatacgtat 2354701 acagccgtta gacacaaatt ttcctactga ttcctctcgg tttgtcccat gaattccata 2354761 aatccgcccg tccgttcctt tcgcgtcaaa tccgatccat cttgccccaa gcgggttatc 2354821 aggagatccc ccttcaatat ttttctttct gtagtaagga ttttccgctt ttaccgttac 2354881 cgaaaactct ccttcaggcg tcaaatcatc tgtttttcca gtcgccacac tatacacgcc 2354941 ttctactttg ttgtcgagga taacagcaag ttcatttgtt cgcttgttga caataacata 2355001 cggatcaccc ggcagcggat tttcgccgag cggccaaatc ggtgaaatca tcatgaaaat 2355061 cgaacataag aaaaaacgca taagctcctc ctttttcatt aggttgacca atgaaggaag 2355121 agctcatgcg aatcatccga gtgatttttg cgcttttatt cctttaaaat aacttttaat 2355181 cactaaatat tgttccattt cgccgagaag atggaagaga gcggccctcg cttcaaattc 2355241 ctctctagtc gcaggaagcg gcatctcctc aaattctttt ctcatgtcag caagtctttt 2355301 cagaaatttg tatgctgtat tcccagggtg tatcgcctcc cgcaaatcat gaataaattc 2355361 agcgatcatt tttccctgat ctaccgtgat ggagatcgat gtcactttag ggagaaggcg 2355421 ttcgataatt tcaaattgct tttctctcat tttaaaataa tgataatgca gattttcata 2355481 acgcaaaatg tggttttgca catctcgata tgccaggttt ttagcctccg taatgagctg 2355541 gtgcgtttcc ggaatttctt ttcctgacca atcttgctca ccagttaaca aataccgttc 2355601 gatttctgca aaaatgacag caaagttatc ctctatcttt ttgcggtagg caatcagttt 2355661 ccggtcaaga ctaggcatat acaagttcat caatagagcg acgccgatgc caaccgtaat 2355721 cagctgaact tcattccaga tgaaagtagg cgtaatgccg ccggacatgt ataaatgaag 2355781 gataataaca gaactggtga cgataccctc gttaattttt aacagaaccg ttatcggaat 2355841 gaatatcaaa agaagcgctc cgatcacaaa cgggtggtag ccaataagct cgaaaaagag 2355901 ataagaaaaa gcaattgcca gacagcatgc cgaaaagcgg gcccatgagg cctgaagcga 2355961 ccgtttttgt gtgatttgta tgcacaaaat ggtgatgatt cctgctgatg cgaagttttg 2356021 caaatgcaat aactggctta tataaatagc caaagctgtt ccaagcgcgg tctttattgt 2356081 gcggtaacca attttaaaca tgtcggactc catttctatt tgtttcttca ataaaaaaga 2356141 agaggcggcc agccttcttc ttttttatat tctataatat tttctctaaa aagtcctgcg 2356201 ctcttttgga ttttggcgac ataaaaaatt ccttcggatt gccgtcttcg acaatcattc 2356261 cttggtccat aaacagcaca cggtctgcca cttcttttgc gaagcccatt tcatgtgtga 2356321 caatcaccat ggtcatgccg gtttcgacca gctctttcat cacctgtagc acttctttga 2356381 ccatctctgg atcaagggcg gaggtcggct cgtcaaacag catgatgtcc ggattcatcg 2356441 caagagccct ggcaatcgcg acacgctgtt tttgtccgcc agacaaacgg tttggatagt 2356501 catttcgctt ttcaaacaaa ccgactttgc ggagcaggtc ctcagctttc tcctgtgcag 2356561 cctgttttga ttcttttttt acattgacag gcgcgtacat gatgttttcg agaaccgttt 2356621 tgtgcggaaa gagatgaaaa tgctgaaaaa ccatcccgat gttttcccgg acctttaatg 2356681 tgttggtttt cggcttcgta atctctgtgt cttttattgt aatggttccg ccgttaggct 2356741 tttccaacag gtttaaacag cgtaagaacg ttgatttgcc tgagcctgaa ggaccgatca 2356801 cggcaacaac ctcaccctca gcgattgttg ttgaaatgtt ttttaatact tcgtgtttcc 2356861 caaatgattt tgacagcttt tcaaccttaa tcattggatt tcagcttcct ttctacagcc 2356921 ttgccgataa acgttaaaat caggacaagc acataataaa tcaatcccgc gataatgagc 2356981 ggctcaaggt aattgtaagt ggcggcgcca gcttgatatg cgcgtctcat gacatcacca 2357041 agcccgatga cggtgacgat cgccgattct tttgttaacg taattaattc attcacaatt 2357101 gcaggtgata tatttttgaa ggcctgcggc agcagcagat ccttcatcat ttttccatac 2357161 gggacaccga gtgcaacagc agcttctttt tgccctttat caatggcatt gattccggct 2357221 ctgataattt ccgatacata agcggcggaa ttcaaagaca atgcgacaac cgcagcccaa 2357281 aactggtcaa tttgaaatcc gagcagctga ggaaggccaa aatagacaat cataagctgc 2357341 agcactaaag gcgtgcctcg gaacactgat gtataaaaat cagcgatcca gataaacggg 2357401 cggaatgtgc tgatcttgca taagcttagc acaataccga gtataagtcc gataatagca 2357461 gatacaacaa caatttttaa tgtaattgcc aagccttcta atataaaagg aatttggggg 2357521 atcgttgctg aaaaatccaa attcatagcc tttgtctcct tttcttacag gaaaaaagtt 2357581 tcctattcaa taaaaaggct caacgaaaaa gttgagccgc ttttttttac ttctcgccag 2357641 tgaaccattt tttcttcaat ttctcaagct ctccgttatc ttccatttcc ttgagcgctt 2357701 tattgaattt gtctgtcagt tcactgtcct ttctgaaagc aattgctgaa ccggcttctt 2357761 ccgctttcgc atcaggaatc acaaagcctt gcaggtcatc atttgatttg aaataccctt 2357821 ctgcaacaat gtcttcaata atcgcggcat cgaagcggtc agatttgatt tcctgcacca 2357881 aatcagaaat tctgttgcgg tcttctgttt taaaaccata ttccggagaa agctctttcc 2357941 ccttctcttc ctgaatagag ccaagctgaa cgccaactgt ttttcctttc aggtctttca 2358001 aagattgaat gccgctgtct tttttgctga caatcatatg gttcgctgtg taatacacat 2358061 cggaaaaatc aacttgtttt ttacgctcag gcgttggtgt cattcctgac agaacgagat 2358121 ccacctgttt tgatttaagc gctgtaatta agctgttgaa gtccatatcc tgcacttcaa 2358181 tttcatagcc tgccttcttt gccagagctt ttgccagctc tacatcaaag ccgacaatat 2358241 tatctccttc tttatattca aacggtttgt aatccgccga agtacccata attaattttt 2358301 tctttccgct ttctgaacct gaattgcttg agccgcacgc agttaatgca aaggtgatgc 2358361 aagcagccac aagtaataag agccattttt tcatgatcca tttcccccgt attcattact 2358421 tttggtgtat ttgaatattt attcgttaat ttgtatttta aacagtttct catttttatg 2358481 caatactatt tttaaaaatt atctttaggc ttatctttcc agtgatctct tctgatatta 2358541 ctagataaaa attaaatcgc tgtacaatcc gattgaataa tcccttaata tttattcata 2358601 tatccttgga aatttatgca caaaaaaacc cgggctgctt tgagcatccg ggttgttcgt 2358661 cttatacttc ttcacaatat tcttcaaagg cttcctgcag ctttgccact acagccatcg 2358721 gctcatggcc ttcaatttca tgacgctcta ccattttcat gatctttccg tctttcaaaa 2358781 tcgcaaagga cggagaagat ggtggataac cttcaaaata gtcacgcgca cgcgctgtcg 2358841 cttctttatc ctgtccggca aaaacggtga cgagctgatc aggtctttta tcatagtgaa 2358901 cggaatggta ggctgccggt cttgcaattc ctccggcgca tccgcaaaca gagtttacca 2358961 tgacgagcgt cgttcctttt ttcgtaagtg cctcatccac ctcttcggct gttttaagct 2359021 cggtgtatcc ggcagctgtt atttcttgtc tcgcttggcg gacaatatca ttcataaata 2359081 aattaaagtc catgttcaat gaagacctct cctttttcat catctgttct tatgatagca 2359141 aggaaacgtc catatcggca aatgactttg cttcgccgtg cacttttttt gctcttcgtt 2359201 tactgcttac agaaaaaggg gattatataa ccagaagtaa aataaaggag cagttgtata 2359261 tgagccaccg gaaagcgtta ctgattcata acggaaatgc cggcaacaaa aatatagaaa 2359321 aagcacttgg tgctgtggtg ccggttttat ctcaccattt agatgaggtg attattaaac 2359381 agacaaagaa aaaggatgat gcgtatcatt tttgccgatc cattgatgat tctgtcgaca 2359441 ccgtcttcat tctcggcggc gacggcacga tccatcaatg cataaatgct atcagcgctc 2359501 tagaaagaaa acccgctgtc ggaattttgc ccggcggcac gtgcaacgac ttttcaagag 2359561 tgcttggcat ccctcaaaat cttgcaaagg ccgcggaagc acttatggcg ggaaaaaaaa 2359621 ccagcgtaga cgtatgtcag atgaatgacc gttatttttt gaatttctgg gggatcggct 2359681 taattgcaga aacgtcgaat caaatcaacg aaacggaaaa agcattattg ggaaaaatca 2359741 gctattttac aagtgccttg cgaaccgtct catctgctgc atcgtttccg atgacattaa 2359801 aaattgatgg agaagaaatt aaagaagaag ccgttatgct gcttgtgatg aatggccaat 2359861 acattggaac gaatcgaatt cctctgcccg atgccagtat tgaagacggc ttacttgatg 2359921 ttctcatatg ccgcaatacc aacctcaccg cgctgcggga gctgatgagc atggaacaag 2359981 gctcaattga tcgttttact ggagagttgt cctatgtcca ggcttcccgt atcgagattg 2360041 aaacagacac tgccaaaaag gcggatatgg atggagaagt ttatacacat acacccgcag 2360101 tcattcaggt cctgccacag catatcgaca tgcttgttcc cgcaaatgaa taactgtcat 2360161 aaggctttag aaagattttg caaatccgtt gactctcccc taggaggagg tcttacagta 2360221 taagggatac acacttgaaa aaggggaagt catatggaga agaaaaatat taccttaact 2360281 atattattaa ccaatttatt tattgctttt ttggggatcg ggcttgtgat tccagtaacg 2360341 ccgaccatta tgaatgaatt gcatttatcg gggaccgcgg tcggctatat ggttgcctgc 2360401 ttcgctatta cacagctcat tgtctcacca atagccggac gatgggttga tcgcttcggg 2360461 cgcaagatca tgatcgtaat cggcctgttg ttctttagtg tgtcggagtt tttgttcggc 2360521 attggaaaaa cagttgagat gttatttatc tcccgtatgc tgggcggtat cagcgcagcc 2360581 ttcattatgc ccggggtcac ggcttttatt gcagatatca cgaccattaa aacacggcca 2360641 aaagcgctcg gttatatgtc agccgctatt tcaacaggat ttattatcgg ccccggcatc 2360701 gggggatttt tagcagaagt ccattcccgg ctgccttttt tctttgcggc agcttttgca 2360761 ctgttagcag ccattttatc aatcctcacg ctgcgcgagc cggaacgaaa ccctgaaaat 2360821 caggaaataa aaggacagaa gacaggcttt aaacgaattt ttgcccccat gtatttcata 2360881 gcttttctca ttatcttaat ttcgtctttt ggtttagcat catttgaatc tttatttgca 2360941 ttattcgtgg atcataaatt cggatttacg gccagcgaca ttgccattat gattacagga 2361001 ggagcgattg ttggcgccat tacgcaagtc gtcttattcg accgcttcac aagatggttt 2361061 ggcgaaattc atttaattcg gtacagctta attctctcga cgagtctggt attcttgctg 2361121 acaacggtac attcatatgt tgcgattctg ctggtgacag tcaccgtatt tgtcggattt 2361181 gatctcatgc ggcctgcggt aacgacttac ctgtcaaaga ttgcgggaaa tgaacagggg 2361241 tttgccggcg gtatgaattc aatgtttaca agtatcggca atgtattcgg gcctattatc 2361301 ggcggaatgc tgttcgatat agatgtaaac tatcctttct actttgcaac ggtcacctta 2361361 gccataggga ttgcactgac cattgcttgg aaagcgcctg cacatcttaa agccagcacg 2361421 tgataagaag cgcattcttt gtgtactgca aagaatgcgc ttcttcttta tactgatgat 2361481 agaaggagtg atggcatgaa ggaatcgtat tactcaattg gggaagtatc aaaactggca 2361541 aacgtgtcga taaaagcgct ccgttattac gataaaattg atttatttaa accagcctac 2361601 gtcgacccgg ataccagcta ccgctattat acagattctc agctcattca tctggatttg 2361661 atcaaatcat tgaaatatat cggcacacct ttagaagaga tgaaaaaagc acaggactta 2361721 gagatggaag aactgtttgc tttttataca gagcaggaga ggcaaatcag ggagaaatta 2361781 gactttttat cagccctgga gcaaaccatt tcattggtga aaaagcggat gaaacggcag 2361841 atggaatatc ccgcgctcgg tgaggtgttt gttttagatg aagaagaaat acggatcatt 2361901 cagacagagg cagaaggaat cgggcctgaa aacgtgctca acgcctccta cagcaaatta 2361961 aaaaaattta tcgagtcagc agatggattt acgaacaata gctacggcgc tactttctct 2362021 tttcagccct acaccagcat tgatgaaatg acttaccgtc atattttcac acctgtattg 2362081 acgaataaac agatttcatc aattacgccg gatatggaaa tcacaacgat ccctaaaggg 2362141 aggtatgcgt gtatcgcgta taatttttcg cctgaacatt attttctcaa cttacagaag 2362201 cttatcaaat atatcgcgga ccgccaatta acagttgtca gtgatgtata cgagttaatc 2362261 ataccgattc attactcccc gaaaaaacaa gaagaatatc gagtcgaaat gaaaatacgg 2362321 atcgctgaat aataaagcat agaaaaagag cattttttga aacaaaactt caaaaaatgc 2362381 tctttttgct tatttagtaa acagatgtct tctcgtcaat cgattctaaa atttgtttca 2362441 ctcgtccgag gaatcgtccg cacacgagac cgtcaagcac tctgtgatct aatgacaggc 2362501 acagattaac catgtctctg acagcaatca tgccattgtc catgacaacc gggcgtttga 2362561 cgatggattc tacttgaaga atcgcagcct gagggtagtt gataatgccc atcgactgaa 2362621 cagacccgaa cgaacctgtg ttgttgacgg taaacgtgcc tccctgcatg tcatctgcag 2362681 tgagttttcc gtctcttact tttttagcta ggccggtaat gtctttcgca atgcctttaa 2362741 ttgttttttc atcagcgttt ttaatcaccg gaacaaataa agaatcctct gtggcaactg 2362801 caattgaaat attgatatcc tttttctgaa taattttgtc ccccgcccac atgctattca 2362861 tttgcgggaa ttcttttaac gcctgagcga ccgcttttac aaaaaaggcg aagaacgtta 2362921 aattaaagcc ttctgtcttc ttaaaagaat cttttatact gttgcgatat gcaaccatat 2362981 ttgtgacgtc gacttccatc atcgtccaag catgcggaat ttctgttttg cttcgcttca 2363041 tattggaagc aattgctttt cttacacctg tgacagggat ttctttatca ccggctgcag 2363101 acgcaggata tgacgtctct tcttttggct caggttttga tgcagacttc ggtgcaggag 2363161 ctgctgtttt cagctcctca ggattctgtt cttgcacgcc gcctgtttca attaagcgct 2363221 gaatatcttt tcgtgtgatg cgcccgccgg caccagttcc tgtcacttga tcgaggtcaa 2363281 tgccgtgctc tccggccaaa cggagaacag ctggcgagta gcgcttttta ttgggctgat 2363341 cggctgctcc agcacttttt gcaacagggt tctcagcggc ttctgatgct gctggctgtt 2363401 cttgtttttg ttcagccgga ttcgcgcctt ctgtttcaat tttgcaaatc atttctccga 2363461 cttgcagggt ttggccttct tctcccacaa gctctgttat cgtaccagta aaagaagacg 2363521 gaacctctgc atttacctta tctgtcatga cttccgcgat cggatcgtat ttgttcactt 2363581 tatcaccggg ggcgacaagc catttgctga tcgtcccctc tgttacgctt tctccaagct 2363641 gcggcatcgt catttgttca attgccatga ttgtatcctc ccttacgtct ttaaaactcc 2363701 gctaattctc tcatcgccgc ttccacttta tcagggttga ccataaagta tttttccatt 2363761 gtcggcgcat aaggcatagc cggaatatca ggacctgcaa gccgtttgat cggcgcgtct 2363821 aagtcgaaca gacaatgctc ggatataatt gcggctactt cgctcatgat gctgccttct 2363881 tttgtatctt ctgtgaccaa aagaaccttt ccagttttgg acgcagcttc gatgatggct 2363941 tctttatcaa gcgggtaaac tgttcttaaa tccaccacat gcgctgaaat gccatctttt 2364001 tcgagacgtt ctgcagcttg taaggcgaag tggacacaca ggccgtatgt gatcactgtg 2364061 atgtcgtcgc cttccctttt tacgtccgcc ttgccgattg gcaggacata atcatcagcc 2364121 ggaacctcgc cctttatcag acggtatgcc cgcttgtgct caaaaaacag cacggggtct 2364181 tcgtcacgaa ctgcggcttt taagagccct ttcgcgtcat atggtgttga tggcatgaca 2364241 attttcagtc cgggctggtt ggcgaaaatt gcttcgactg attgagaatg atacagggct 2364301 ccgtgcacgc ctccgccgta tggcgctctg acgacaatcg gacagctcca gtcattgttg 2364361 ctgcggtagc ggattttagc cgcttcagaa ataatttggt tgactgccgg cataatgaaa 2364421 tcagcaaact gcatttcagc aatcggtctc attccgtaca ttgccgctcc gataccgact 2364481 cctgcgattg cagattcagc aagcggcgta tccataacgc gctcttcccc aaattgttca 2364541 tagagtcccg ctgtcgcttt aaacacaccg ccttttcttc ctacatcttc cccaaggacg 2364601 aaaacgcgag aatctcgttc catttcttct ttcatcgcca aattgattgc atcaatatat 2364661 gacattactg acatttgttc ttcctcccta cttcgcataa acataatcaa gcgctgactc 2364721 aggagctgca tatggggcgt tctccgcttc atccgtcgct tcatttacga ttgccataat 2364781 ttcatccagc atggtttgtt ctatctcatc ggacagcagg cctgtttcct ttaagtaagc 2364841 ttgataagta agcaggggat cacttttttt cgcttcctct acttcttcac ggcctctgta 2364901 gctgctgtca tcgtcatcac tggaatgtgg tgtaaggcgg taagaaatcg tttcaattaa 2364961 tgtcgggcct tctcctctgc gtgccctttc gcgtgcttct ttaaccgctt gataaacttc 2365021 cagcggatca tttccattca cagttacgcc aggcatccca tagcctatgg cacggtcgga 2365081 aatgttctca catgcgactt gcttatcgta aggcactgag attgcgtatt tgttgttttc 2365141 acacatgaaa ataaccggca gcttatggac agcggcaaag tttgcccctt catggaaatc 2365201 gccttggttt gaagaccctt ccccgaatgt aacaaaggct gcgatatcct ttttctccat 2365261 acgtcccgca agcgcaatac cgactgcgtg cggcacttgc gttgtaaccg gagatgatcc 2365321 cgtcacaatg cggtttttct tttgtccgaa atgtcccggc atctggcggc ctcctgagtt 2365381 cggatctgct gcttttgcaa acccggacat cattaagtcc tttgctgtca tgccaaacgc 2365441 gagcacgaca cccatgtctc tgtagtacgg caatacataa tccatttcac ggtcaagtgc 2365501 gaaagccgct cctacctgtg ctgcttcctg tccttgacaa gagattacaa atggaatttt 2365561 gccagaacgg tttaacagcc acattctttc atcgattttt cttgctaaca gcatggttct 2365621 atacatatca acggcttcct gatcagtcag ccctagtgct tgatgtcggt ttgtactcat 2365681 tcaagcccct cctttatgct tttaaaaatg aatggctttg ccatctgcgg caagcgcagc 2365741 ttctccaatt gcttcagaaa gcgttggatg cgggtgaatc gtttgcccga cctcccacgg 2365801 tgttgcgtcc agcactttgg caagacccgc ttcagaaatc atgtcggtga catgcgggcc 2365861 aatcatatga acgccgagaa tatcatctgt atctcggtca gccacgattt tgacaaaacc 2365921 gtcgctttca ccgtatacaa gcgcttttcc aatcgccata aatgggaact tgccgatttt 2365981 gacattatgc ccgttcgcct ttgcttcgtc ttcggttaag ccgacactgg cagcttcagg 2366041 gcttgagtaa atgcacttcg gcacaagcgt cggatcaagc ggatgcggat tgagacctgc 2366101 aaaatgctca acagcaataa ttccctcatg tgaagcaacg tgagctaact gcaggccacc 2366161 gattacgtct ccgattgcat aaatatgaga ttccttcgtt tggcagcttt cattgactga 2366221 aatcatgcca ttttcagtaa caatatcggt gttctctagg ccgatgcctt cgatatttgc 2366281 ctgtctgccg atggaaacaa gcattttctc agcagaatag gtaacggttt ctccgtcttt 2366341 ttccgcttgt atgctgatat cgtctgatgt ttttgtcatt gtgtcaggca gcacttttgc 2366401 ccctgttatg aactggatgc cttttttctt aagaagactt tccatttctt ttgaaatctc 2366461 tagatcttca gtcggcaata tgcgatccgc gtattcaata accgttacct taacgccaaa 2366521 atcatgaagc atagacgccc attcgatacc gataacccct ccgccgacaa tgatgattga 2366581 ctgtggcagc tcctccattt ggagcgcctc atctgaagtc agtacagact taccgtccac 2366641 ttcaagaccc ggaagcattc tcggtcttga tcctgttgca atgatcactt gtttcgggat 2366701 cagcatgtca ttttcttcgc catttccccg ctcaacagaa attgttcccg gcagcggaga 2366761 gaagattgac ggtccaagga tacgtccata tccggtgtac acgtcaattt ttcctttttt 2366821 cattaaatga tttacacccg ctgcaagctt atcaacaacg gcttgcttac gctgctgcac 2366881 tttttcaaag ttgagggaca cgccagccgt ttccactccg aattgatcgg cttcacgagc 2366941 tgtccggtat acctctgcgc ttctaagcag cgctttactc gggatacagc ctttatgcag 2367001 acatgttccc ccgagttttt ccttttccac aacggctgtt tttaagccga gctgagcggc 2367061 tctgatggcc gcaacataac cgccggtacc gccgcccaga atgactacgt catactcagt 2367121 tgccatggtg actcactcct gtctgtctat tcaatacgat attgtttgga ttgctcttcg 2367181 ccctgcaata ctcttagcgc cccttgggca agagactgca gttcattttc acccggataa 2367241 actaaaacgt ctgaaatcca atctatgtat gatctgatag cagaaacaaa gctttttccg 2367301 tacgcaaggc ctcccgtcag cacaatcgct tcaacttcgc cttttaacgc cgcgctggct 2367361 gccccgattt cctttgctac ctgatatgcc atggcatcat aaatgaagcg ggctttttca 2367421 tcgccccctt gaatcatctg ttccactttt actgcatcat ttgtaccgag atagcctaaa 2367481 agtccgccgg tgccaacaag ctttttcatg atttcttctt ttgtatattc ccctgaaaaa 2367541 catagatcaa caagatctcc cgcaggcact gttcctgctc gttcaggact gaatggtccc 2367601 tcgccgtgca ggccgttatt gacatccacc actcgcccgc ggtcatggac gccaattgta 2367661 atacctccgc ccatatgggt aataatcatt ttcatgttct catatcgttt gccaagggag 2367721 gctgccgctt tacgagcgac agctttttgg tttaacgcat ggaaaatgct tttcctttca 2367781 atttcaggca tgcctgaaac tttcgcaagc actgacattt cgtctacgac aacagggtcg 2367841 acgatatacg aagggatatt caggccgtca gcgatttccc gcgcgataat gccgccgaga 2367901 ttagaagcat gctgaccggc gtagccgctt ttcaaatcct caatcatctc atcattcact 2367961 acgtaggtcc cgccttcaat tggccggaga aggccgcctc ttgcgcagac tgcatcaaac 2368021 tttgaaatat tgattccctg ttcatgaagc gtttcgagaa tatggttttt acgaaattca 2368081 tactgatcaa taattcggtc aaatcgctgc agctcttcta tgttgtgtct caatgttttt 2368141 tcaaaaatgc ttctttcgtt atgaaaaaca ccgattttcg ttgaagttga gcctggatta 2368201 attgtgagaa tgcgtttttc gtcatgtagc actttcataa cctccagatc aatttcttaa 2368261 cgtctgctta atacactgtg gccgttttgc aaaaactggc ttcttgagcg gcgcatgcgt 2368321 tcaatccgtt cctctgctaa gcggtcagcc gctaaatatg caggaatgcc gtcacgctga 2368381 gaaatctcaa gtacacgctc gatattgccg taaatgcctt caactttttt caatgcacgt 2368441 tctgcattat agccgtaaag ctcatctgcc acgttgatga caccgcccgc gttaatcacg 2368501 taatccggtg cataaacgat gcccatttcg tgaatttgat caccatggcg tgtctctttt 2368561 aattggttgt tagccgcacc tgcgatcact ttcgccttca gctgtttaat ggtgtcgtcg 2368621 ttaatagtcg caccaagggc acacggcgca taaatatcgc agtcttgtga ataaatgtca 2368681 tcaggatcta ccgcacgggc gccaaaatct tcaactgcac gctgtacaga ttgtttgttg 2368741 atatccgtaa cgattaagtt tgctccttct tcatgcaggt ggcggcaaag gttataggct 2368801 acgttcccaa caccctgtac agcaatggtt tttccttcaa gagagtcggt tccgaaagca 2368861 gctttagctg ctgccttcat tcctctgtac accccgtacg ctgtgactgg ggacggattt 2368921 ccagaagagc cgaaagcagg agaaatccct gtgacatagt ctgtctcatc atgaatgata 2368981 tccatatcct cgaccgttgt gcccacatct tcagccgtga tgtatctgcc attcagtcct 2369041 tgaatatagc ggccaaacgc gcggaacatt tcctcatttt tgtctttgcg cggatcgccg 2369101 ataatgactg tttttccgcc gccaaggttt aagcctgccg ccgcgttctt ataggtcatg 2369161 cctcttgcca atctgagcgc atcttcaatt gccgcttctt cattttcata tgtccacatt 2369221 ctcgttccgc caagcgccgg accaagcgtt gtatcatgaa tggcgataat cgcttttaat 2369281 ccagattgtt catcctggca gaataccaat tgttcgtaat cgtatttctc catatattta 2369341 aaaagttcca tgttcgttcc tcctaatgtg tgtattcttc agatgcgcat attgccagcg 2369401 caatggaata cagtttattt tcagcagagt ccgctctgct tgttaaagca atcggtgctt 2369461 ttgctcctgt aatgacagcc gccacgctgg ccttggcaaa ataaatcagt gatttatata 2369521 aaatattgcc ggcctcaatt gttgggacga gaaggatatc tgcgttgccc gctacgtctc 2369581 ccgaaatttt tttctgggcc gcggcaattt gtgaaactgc gttatccaaa gcaagcggtc 2369641 catcaacaat gcagcctttg atctggcccc ttttgtacat ttgagctaga gcagctgcat 2369701 tcacggtcgc ttccatttta gggttcaccg tttcgaccgc tgcaagggca gctgcttttg 2369761 gcatattgtt ccccactgca tgggccacat gaacggcatt ttgcaaaatc tgccggagct 2369821 cttccagcga aggagcaata ttcattgccg aatctgtcac aaacatcagc cggtcaaaat 2369881 ccggtatatc gaagacagcc acgtgagaaa ggacacttgc tgaccgaagc ccctcctgtc 2369941 tgttcaatac cgctttaagc aaaacagaag tcggcacatt gcctttcatt aaaacgtccg 2370001 ctgttttatg atgcacagca cgaaccgcta atttcgccga ttcctcagga gtattggcat 2370061 ggacgatttc cacttgatgc ccttgcatgg atgatgtcag ctcgttcagt tttttgctgt 2370121 cgcccgttaa caagaaacgg gcggataggt gctcggctgc cagctttaca gcccggatca 2370181 cttcctcatc ctcagcatga gcaaccgcaa tggtcttatt tttgtgtatc gacgctttgc 2370241 cgattaaatc tttcagcttc atctgttacc acctttcttg tttcgactcc gccttttatt 2370301 atgcaagttc catgccagct cttaagggtg ctgtcatacc aggtataccg aaacattcgt 2370361 gcagatgttt gcgtttattc tgcaaattat tgcatgcctt catttgcaag gccatattta 2370421 tccattttgt aatataaatt ccgaatgctg acaccgagag cttttgctgt ttttgtccgg 2370481 ttaaaatgat gcttttcaag cgtttgctgg atcaaatgcg cttcaaattt ttctactgcg 2370541 acagacagct tttcgccttc aatatccgga aaatcaaaac ctgttccctg atctgtgtca 2370601 ttttcttttt gctcaagttc gaatacaggc aagtgatctt tttcaatcca ttccatatgc 2370661 ggattcagaa aaatcatggc tcgtccaagg acattttcaa gctcccggac attcccaggc 2370721 caatggtagg cagataaggc gcgcaaggct tgctgtgaga gcccttttac attcctgccg 2370781 taatcccggt tgatcttttg gataagtctg acgctcaatg cttcaatgtc ctccaaccgc 2370841 tgccgcaaag gcgggatgga gatcggatag cgattgatcc ggtaatacag gtcttcccgg 2370901 aatgttccgt ccgccatcgc cttttcaata tttacatttg tcgccgcgat cactctgacg 2370961 ttgacaggga tcgctttcgt gccgcccact ctgacgattt ccttttcttg aaggacgcgt 2371021 agcaatttgg cctgcatatt ttgtgtcagc tcaccgattt catctaagaa aatactgccg 2371081 ttatttgctt cctcaaataa acccttttta ccgccgcgct tcgctcctga aaacgcacca 2371141 tcctcatagc cgaacaattc tgattcgagc aggttttcag aaagggctgc acaattcacg 2371201 cgaataaatt tattgtattt ccggtcactt tcgttatgga tggcatgggc gaacagttct 2371261 tttcctgttc ctgattcccc gcgcagcaag atggttgccg gtgttttcgc accgagcttc 2371321 gcctgctcaa gcgcaaccag catttgctcg cttttgccga taatgtcgtc aaacgtgtat 2371381 ttcgcttcaa gcgtgcgaat aatttgtctg gcgcgattaa gctccgctgt cagcatttta 2371441 atttcggaaa catcgtgaat cacgccgacg ctgcctttca aaatcccgtc cacaatcacc 2371501 ggtgctacat taacgatcac ttctttttca ttcgggccga ccttcattct gacaccgcgg 2371561 acaggacgtc ttgtttcaag cacctttaaa tgcatgcttt cgccttcgga aatatcagtg 2371621 tttgcaggct tgccgatgac ttctttttca gaaagccccg tcattttcgt atacgcttta 2371681 ttgattagca ggccgatgcc gttttcatca acgacagaaa tcgcctcatc ggaggattga 2371741 ataattgcct ccagcatcgt acggacctgc tttaagttgg tcacttcctc tgccagctcg 2371801 accgcatcag tgatatcttt aaacacacaa agagccccga gcagacgtcc gccttcatca 2371861 ataatcggca gtcttgtggt cacaatttgc aaatgatcgc ctaacagctg cttctggttg 2371921 tattcaggca ctcttgtttt taaaatccgc ggcatcttag tgctcggaat cacttctttt 2371981 attgggcgcc caatgacttc ctcacgtttt tttccgacca ttttttcggc catatggtta 2372041 aagagaatga tttcttcatt gatatcaata aaaatcattc catcatgggt ggaattaaaa 2372101 attctgtcat atttataggt ttgctctttt agcatttgaa tcaggtgctg cttttcttcc 2372161 atcagctgaa aaacgatgta tgccattttt cccggcatga caatggtatc ttcatgcttt 2372221 ctttgaagga gctcgtcaaa cacggcttga tcgccggtag tatgaatgac gatatccggt 2372281 ttttgttgta tgtaaggttt ccaatcagat gatacggcaa tcccatactg ttctgcttct 2372341 ttcaatcccg gcgcctcggg gtctttgtca actacggcaa tgatatctat gatggctgtt 2372401 ttaatcagaa tatgtaataa cgccgttccc cttttgccgg cacctactat cagtaccttt 2372461 tgcatcccga tacccctttg tatgaaaaaa tttgcacacc tatttattcc gttgcaataa 2372521 tttgcacaac cctatgttac cacgttttct tctcttgaca aaatattttt tccgctggac 2372581 aataaaggaa atgaaaagat aaaggggttt tctgaagatg agccgacttc ttgcgctttt 2372641 aatattagtc atccccgggg ctatttctgc tttaggcatt aaactgatga gagatacact 2372701 tttcggccat acaatcaagc cattttcagc tctttggctc caagggttgt caggattcat 2372761 cttttttgcg atcggcctct atgtgctggc cgggttcatt ttatacagag acagaaaacg 2372821 caatcaagtc agcccgcgat tcagaaaacg atagctgaaa aaaagccgga gaatgctccg 2372881 gctttttttg ttgcattatt cgtcaggcaa aacggtcttg gcaatcgttt tgtctaacgc 2372941 ttcatagtca taataagaaa tcgtatcgta cagttctttt cgtgtctgca tatcatgaag 2373001 tccttctttt tgtgagccgt gctccttcat caaaccaaac atccgctcac aagcttttgc 2373061 cgccgctcga agcgaggtga caggatatat caccatgtga aaccccatat cttcgaattc 2373121 atcggcacga taatatggcg ttttcccaaa ttcagtcata ttcgcaagga gcggaacggg 2373181 gatacgctca gcaaactggc ggaattcatt ctccgcctgt agcgcttccg ggaaaattgc 2373241 gtccgctccc gcctcaatgt aagcctctga acgttttatt gcggcatcaa gcccttcctg 2373301 cgccctggca tcagtacggg caacaacaat aagggagggt gccgcttgtt taatggcttt 2373361 tattttttgc gccatttcct ttatcggaac tagctgtttg ccatttaaat gtccgcattt 2373421 ttttgggagc tgctggtctt ccatttgaac ggctgctacc ctggcttcaa gcatctcccg 2373481 ggctgttcgg gcggcattta agacaccgcc aaatcccgta tcgatatcca caagcaaagg 2373541 cagatcagct gcacgcacaa gatctttggc ccgttcagct atctctgccg atgtgatgat 2373601 ccctaaatca ggcagccccc tgctggctgt ataggcagca ccggacaaat aaatagcaga 2373661 aaaaccggct tctttcgcaa gcaaagcggc catcccgtca tgggcgccgg gaatttgaag 2373721 aatgtccggt gctgacatca gcttgcggaa acgcccggca agctcctctt gtgacgattg 2373781 cttattgacg atccacgaca tgaaacaaaa tccccctttt acatgcagaa catgtctacg 2373841 aattcattta cgcgcatcgt ttgtaatgtc tcatagctgg tacagcgctc ataaatgtgt 2373901 ttgtgctgtt tatcaggaaa atgggttttg agattgtcag aaaacttttc cagcagtttc 2373961 ggcactgctt cctctcttcg aaaacgatgg ccgaggggaa actcacattc caccatttcc 2374021 gtgctcgttc catctttaaa atgaacctga acggcatttg agatggagcg tttatcaggc 2374081 ttcaaataat cctcggtata tgttttattt tcagtcactt ccattttatc acgaagttta 2374141 tctattctcg gatcattcgc tgtttcagct tcataatgct gtgcggtgat atcaccaaaa 2374201 agcaaaccga ttgctgtaat gtattggagg cagtgatcac ggtctgccgg attgtggagc 2374261 gggccttttt tatcaatgat tcggatagct gattcatgcg ttctgatgac aactcggtca 2374321 atctcgtcaa tccggttctt tacctgcggg tgaagaatga cggcggactc cgccgctgtc 2374381 tgggcgtgaa attccgcagg ataagacact ttaaataaca cattttccat gacataagcg 2374441 tcgagcggac gggcaagctt gatctctttc ttattgaata aaacgtcttg gaacccccaa 2374501 cccggtgcac tcaaggctgt cggataaccc atttcccctt ttaacgacat cagcgccaaa 2374561 tgaacacctc tgctcgttgc atctcctgcc gcccatgatt tacgcgagcc tgtattcggt 2374621 gaatggcggt atgtcctcaa tgctgcattg tcaatccatg cattcgaaag cgcatttttg 2374681 atttcttctc ttccgccgcc caaaagcttt gctgcaacag cagttgtcgc aactttgaca 2374741 aacagcacat ggtcaaggcc aactcgattt aagctgtttt ctaacgccag cacaccttgg 2374801 atctcgtgtg ctttgatcat catctcaagt acgtcgcgta ccgttaacgg ctcttttcct 2374861 tcagacagcc tcactcttga tacataatca gcagcggcaa ggattcctcc caagttatcg 2374921 gatggatgcc cccactccgc cgccagccac gtatcgttgt aatcgagcca gcgaatcatg 2374981 cagccaatat taaacgctgc cctcacagga tcgagaacat atgacgttcc cggcactttg 2375041 cttccattcg gcacagtcgt tcctggaaca atcgggccaa gcagctttgt gcattccgga 2375101 taccgtagcg ccaagattcc gcagcccagg gtatccagca atacatgccc cgctgttgta 2375161 tacgcttcgg cactagtaat ctctttctca agcacatagt ctgtgatttc ttcgataaca 2375221 cgatccgttt tcggcattct accagctcct ttcatgattt tgtttgatat cgcgggccca 2375281 tgtaactgac acggggacgg aagagccgat tattggcatg ctgttcgatc acatgggcgc 2375341 ataaaccgga cgttctcgcg ctgaaaaaga tcggcgtata taaaggaatc ggtatgccga 2375401 gcatccaata cactggggca gcatagtaat ccaaattcgg gtaaagccct ttttccttct 2375461 ccatcagccg ctcacccgct tcgcacatct catataaacg atggtcaccg gctttatcgc 2375521 ataattgctg cagcgcctct ttcatcatga gtgctctcgg gtccattttt ttcatataca 2375581 cccggtggcc gaagcccatg attttttctt ttcttttcag ttttgtttgc aaaagctgct 2375641 caaaatcaga tgtcgttttt gcctccaaaa gcaaatacat cacagcttcg tttgctcctc 2375701 cgtgaagatt ccctttcagg gaagcgacag ccccagtcaa agccccataa agatctgaat 2375761 gtgtagatgc aatgaccctg gccgcaaagg ttgaattcgg catctcatgc tcactgtaca 2375821 ggacgagcga ccggtcaaaa atctgttctt ccaatgaaga cggcaatttc cctgtcatca 2375881 tgtagagaaa attcgcactg taggataggg tttgaagcgg aagaatcggt tctttcttat 2375941 taatgatcct gtagctggca gcagtgaggg caggcatttt cccaagaagc tgataggcgc 2376001 gttctttgtt tgcggaagga gaccgatcat caatttgccg atcatagcca gcaagtgccg 2376061 acaggccggt acgcagacca tccattggat gagtgtcctc agggagcagc tcaagcagac 2376121 ggagatgatc agcaggcagg cttgaggcac tgtttatttt acgttccagc gtttccattt 2376181 cactttcttc tggcagcctg ccctccagca ataaatggac aagctccaga tagctttttg 2376241 tttcagaaag ttctattaaa tcatagcctc ttatcaaaat ctggctggac tgcgtgtcaa 2376301 gataagaaat atgagtttct gccgcaatca caccgtccaa ccctggagaa taatgctgtt 2376361 tctcctccat atcctcaacc tccgtttttg cgttttttgt ctatcaggtt ccgccaagca 2376421 aatacttgga aataatcagt ctttgaatct cgttcgtccc ttcataaatt tgcgtcacct 2376481 ttgcatcgcg aagcaggcgc tcaactggat aatccttcat atagccatat cccccataaa 2376541 tttgaacggc gtctaacgcc gcctttacgg ctgcatcgga agcaaattgt ttagccatag 2376601 acgcttcttt tccacagttt aggccgcggt tatgaaggtc tgcagcgtgg tagacaagat 2376661 gtcttgccgc ctcagctcta gtcgccatat cagccagctt aaatgatatg ccttgattgg 2376721 ctgcaatcgg ccttccaaat tgcactcgct gcttcgcata atcaacggca tgctcaagag 2376781 ccgcctctgc aattccgagg gcctgtgccg caatgccgat ccggccgaca tttaaattcg 2376841 ccatggcaat gtgaaagcca tccccctctt tgccaagcaa attggcttca ggcacttctg 2376901 cattatcaaa aatcagttcc gtagtattgg agccataaag ccccagcttt ctttcttttt 2376961 ttccaacggt aaaaccgggt gtgttttttt caacaataaa agccgaaatc ccgtgcctgc 2377021 cttgatctgg agctgttaaa gcaaatgtga tatagatatc agctgctccg ccattcgtta 2377081 tgaatatttt cgatccgttt aataggtatt tgccgttctt tttgattgct gttgtgcgga 2377141 ggctcccggc atccgacccc gagtgaggct ccgttagtgc aaatgcgccc aaatggtctc 2377201 ctgacgcgag atttggtata tatttcatct tctgttcttc gttgccgaaa tacagaatcg 2377261 gattcgtgcc gactgaggta tgaacggaga gaatcacgcc gacagccgcg ctgattctag 2377321 aaatctcatg aattgccaaa atataagaaa caacgtccgc tccagcaccg ccgtattgtt 2377381 ccggcaccgg tattcccatc agtccgtgtt tacccatttt tttgatcagc tgaaagggaa 2377441 attcgtccgt tttctccatg atttccgcag cgggagcaat ttcttttcgt gcaaaatcac 2377501 gcaccatttt tcgcatcatg acttgctctt gggttacatg caactcggcc acccccggat 2377561 ggaatagact tcaggaagtc ttctcctcat agtcataaaa accgcgtccg ctctttttgc 2377621 caagccagcc tgctttgaca tacttgcgga gcagcgggca aggacggtat ttggaatcgc 2377681 caaggcctga gtgaaggact tccataattg ataaacacgt atccagtccg ataaaatccg 2377741 ctaatgcaag cggacccatc ggatgattca tgcccagctt catcacttca tctattgcct 2377801 ccggcttcgc cactccctca tacacgcaat agatggcttc attaatcatt ggaagaagca 2377861 cacggttgga aacaaaccca ggaaaatcat tgacttctac cgctgttttc cccatctttt 2377921 ccgctaatgc cataacatct aaggccgttt cttctgatgt agccaagcct cgaatcactt 2377981 ctaccagctt cattacaggg acgggattca taaaatgcat gccaataacc cgttgaggcc 2378041 ggtttgttac agcagcgatt tctgtaatag gcaaggaaga tgtattgctg gccaaaatcg 2378101 tatgaggcgg gcaaatgcga tcaagtgttt taaacatctc agtttttgcc gccatgtttt 2378161 ctgcgatagc ctcaatcaca atgtccgcat gctctgcctc ctcaagtgtt tgagaaatcg 2378221 aaatgcggtt gattacgctc ttcacttccg tctcggtcct ttttcctttc tcagcatcac 2378281 gggccagctg tttcttcagc cgtttcaatc ctgcctccgc ggcctctgga ttcacatcat 2378341 acatccgcac ataaaagccc gcgtcggcgg ctgtttgagc aattccgctc cccatctgac 2378401 ctgcgccagc taccatgatt tgtttgattt ccattcaaat cccctttttc atcatgtttt 2378461 aatgaacctg cactaagacg gcgtctccct gtgctgcccc gctgcaaata gcggcaacgc 2378521 ccagaccccc tccccgtcgc tttaattcat aaacaagcgt catgagaatt ctcgcaccgc 2378581 tcgcgccgat cgggtggccg agcgcgatcg caccgccatt cacatttact ttttcaagat 2378641 cgaaacctac gattttttca catgtcaaaa caactgaagc aaaagcttca tttacttcaa 2378701 acaagtcaat atcttggaca gttaaaccat tctttttcag gagcttgtta atagcaaacc 2378761 ctggcgctgc cgccagctcg tgcgctggca ttcccgtagt tgaaaaacca agaattgtag 2378821 ccagaggccg tttgccaagc tcagcagctt tttcctcaga catcagcacg aacgcgccgg 2378881 ctccgtcatt gactccagga gcattgccgg ctgtgataga accgtcactt gcataaatcg 2378941 gagcaagttt tgcgagctga tccagacttg tgtcacggcg aatcgcttca tctttatcaa 2379001 caacgtttgg ttttcctttt cgaccgatcc agttgacggg aacaatttca tcctgaaact 2379061 tcccttcatc ggcggcctta gctgcccttg catgacttct caacgcccat tcgtcctgct 2379121 ctcttcgtga gattgcatat tccttggcag ctgtatttcc gtgaacagcc atgtgcacct 2379181 cgtcaaatgc gcacgttaat ccgtcataca ccattaagtc cctaagctcg ccgtccccca 2379241 tccgtgctcc ccagcgcccg gcgggaacgg catacggaat attgctcatg ctttccatcc 2379301 cccccgcaac aagtatgtcc gcatcctgcg cccgaatcat ttgatcacat aaagtgacag 2379361 cgcgaaggcc ggaagcacag actttattca gtgtttctga cggcacactc caaggcattc 2379421 ccgccagacg ggcagcttga cgggaaggta tctgccctga gccggcctgg acaaccatgc 2379481 ccatgacgtt tccttctaca tcatctccag agactccagc ctgttgcagc gcctccttca 2379541 tcacaatgcc cccaagctca gcagctttca cctctttcaa aactccgccg aatttgccaa 2379601 atggagttct tgcagcactt acaatgactg ttttcctcat ggtttcacct cattcagaag 2379661 atagacagcg cttacaattt ctagttgtct tctatgaatg tatgctttga aacgggcatg 2379721 aatgaatgaa aaaagaaggc tgcgtcaaac agcctccttc taacaactat tcatttttca 2379781 gcaatgccga agccttttct ggaaagtcgg taaacatgcc gtctgctccc gcttcaatga 2379841 gacgcttcat atcttccgga cgattgactg tatacggcct taccttaatc aaaccgttcc 2379901 tcattttctt cagtacttca tctgtgaccc ctgggctgtt tatcttcggg tgatagccgg 2379961 aagccggaat agacgcgata tatcgatctg cctgataaag cacatctgaa gttaatactg 2380021 cccgttcgat atgcggtgca agccgggcgc acagcgccaa gctgtcatga ttaaacgtgg 2380081 ataggatgac tctgtcctct acattaaatc gcttcactgc ctccagcact ttttcttcca 2380141 ttccctcata gcggatcacg ctgtttttta attcaatgtt gatgagaaaa tcctttttta 2380201 ccgcccacga gagcacatct tctagcagcg gcacttttat atcgctgtac gcttgatcgt 2380261 gaccagcggc cgcattcgca gtctttacct catcataggc tgtatccttc acgaatcctt 2380321 taagtgatgt cgtgcgatta agtctttcat catgaattac aacaatgcgt ccgtctttcg 2380381 tcagctgtac atcaagctct atcccatccg ctccggcttc aattcctttt tcaaatgcaa 2380441 gcattgtatt ttcgggaaat tgacctgatg ccccccggtg ggcaaaaatc tttgtcatcg 2380501 tttcacctca aaccctaaag ttttctccat tatacttatt ttgtcggctc cactctagga 2380561 ttaaggctgt atcaatctac tgatcataat aagaatcaat gccattgaca atcgcatctg 2380621 cggccttttg ctggtattct tcacttccca gcttgtccgc gtcagagctg ttcgtgataa 2380681 acccaagctc cgccaacaca cttggcattt gtgaatatgt aatgacgtaa aagtctgatt 2380741 ctttcacgcc cctgtctctc gtttgtaagg aagaaacgag ctgtgactga atatcggatg 2380801 ccagacgccg gctgttctcc ccttcataat cagattgaaa atacgtttct gttcctgaag 2380861 ctgaagcaac ccctgaattc acatgaatgc tgacaaaaag gtcagcctga ttggcacttg 2380921 ccttagccac tctttcctcc aaggtcagaa aatgatcgtc agaccgggat gcaacaggat 2380981 tggctccctc ctcttttagt ttgtctgtca catgctctga gacagccaaa ttaatatcct 2381041 tttcaaagag cccgtttccg accgctccac tgtcttcacc gccgtgtccg gcatcaatat 2381101 acactgtttt cccttctatc ggctctgctg cctgtgcaca aggcgcgagc gtcaaagcca 2381161 atccgcacag cgccaagctc ctccataaca ttctcaactt actccctccg gtcacgagtt 2381221 ctttcgcagc tgaatatctt ccagctgtaa agttccatta tccttctttg tatatttcac 2381281 caggacatgt gtctgatctg gcagtgattc acattcatca cgtttatcct tcggaacttg 2381341 tatcatggtt tcttctccat taagagaaac cgcaatcgta tgaggatcag ccgagccaat 2381401 gtattttccc tcttcggtaa acctcggcac tgagtcatcc gcacttgcaa cactgcaccc 2381461 cgaaagaaag agcgcagtaa acagcaaaag aaccgtttgt ttcacatgac cacctcttcc 2381521 tgatgtttgg cttttatctt tgaccagaat ggagaatttg taaagacaac gcgaatgcag 2381581 gcgagcaagt tccatgattt tcaaaagggc tatacgaccc gatcatttcc tgttgttaga 2381641 aagataacga gcagatttgt ctatgaggat ggctctaatt gaggcgccaa ttagaaaaaa 2381701 ttagcggaaa gaagcaactt tttattcatt ttaaaaaatt tgagaatagg gtgagcaaat 2381761 cgtttgacgg gtgggtcagc caagcgtaac cttttaaagg atatttactt tattgaaaga 2381821 agttaaagcc atgaaaaaat tcgttctgct gctggcggca gctgtcatca catgctccat 2381881 cggccaccaa atcagtggcg gctacaaagg ccccgaaaaa gagcggccaa aacatcactc 2381941 tgcactcaag atattcagtc ggtaaagcag atcaattgca ttaattttta catataggct 2382001 agaatatgtg cgaatccaaa cgaaagaaga tgatcaaatg aatcctaagt ataagccact 2382061 ttttgaacca tttacgttta aaagcggcgt tacaatcaac aaccggatcg cagtagcacc 2382121 gatgactcat tacgcttcta atgaagacgg tacaatatct gaagcggagc tcgactacat 2382181 catcccccgt tcaaaagaga tgggaatggt gattacagcc tgcgcaaatg ttacaccgga 2382241 cggaaaagca ttccccgggc agccggccat ccatgacgat tccaacattc caggtttaaa 2382301 aaagttagca caagccattc aggcacaagg cgctaaagct gttgtacaaa ttcatcacgg 2382361 cggtattgag tgcccgtctg agctcgttcc tcaacaggat gttgtggggc caagtgacgt 2382421 gtttgataac ggcaaacaaa ttgctcgcgc attaacagaa gaagaagtgg aaaacattgt 2382481 gaaggcgttt ggagaagcga caagacgcgc cattgaagcc ggctttgacg gtgtcgaaat 2382541 tcacggtgca aacggctact taattcagca gttttattct ccgaaaacca accagcgcac 2382601 ggatcgctgg ggaggaagcg atgaaaaacg attagccttc ccgctcgcta ttgtcgatga 2382661 agtgaaaaaa gccgcttcag aacatgcgaa gggtgcattc ttagtcggct accgcctgtc 2382721 tccggaagaa cctgagacac cgggattgac aatgactgaa acttatacgc ttgttgatgc 2382781 tttaggggat aaagaattgg attatcttca tatctcactg atggacgtga actcaaaagc 2382841 gcgccgcggt gcagatccga ctcgcacacg catggactta ttgaatgaac gtgtcggaaa 2382901 caaagtgccg ctgatcgccg tcggttccat ccattccgct gatgacgcgc ttgccgtcat 2382961 cgaaaacggt attccactgg tcgctatggg acgcgaaatt ctagttgacc ctaactggac 2383021 ggtaaaagta aaagaaggcc gtgaaaagca aatcgaaaca gtgatcaaag gcacagataa 2383081 agaaaaatat catttgcctg aaccgctatg gcaagcaatt gtgaacacac aaggctgggt 2383141 gccttataaa gattaatgtg caaagactgc cgaaacgatt cggcagtctt ttttcccttt 2383201 atataaatag tttgtgtaca catctaaaca gcaaaagaaa gagctcccca ccaacttcga 2383261 aaagaaaatc caggaaaaac ccctcacgct ttcttgcttt tttctttttc attcgtacgt 2383321 ctccttttta catgaatacg ccttacttac gattttgcag gagaaaggtt tcattttata 2383381 acggacacat ctagggtcga tcatgcttcg tgatcctata agatgtatga atggaccaag 2383441 agtgcaggta ataccgccat ttgctttcct tacttttcaa acctatcctt tactatatgc 2383501 ggatacttaa tattcttctc ccatactaca aatgtcccca aaacaaaacg cctcctattt 2383561 atcagcgcaa actaataaat aaaagacgtt tgatttaatg accacttaat aagctcatgt 2383621 ttaagaagcc ttatgctcta acctcagctt atccgcaacc attgcaatga attcactgtt 2383681 ggtaggttta gcttttgtca tgctgacagt ataaccaaac aacgaggaaa tggaatcaat 2383741 gtttcctctg ctccatgcca cttcaattgc atggcggatc gctctttcta cacggcttgc 2383801 ggttgtgtta aattttttgg cgatgtccgg atagaggact tttgtaatgc tgccgagcaa 2383861 ttcgatgtca ttgtatacca ttgagattgc ttcgcgcaga tagagatagc ctttaatatg 2383921 ggctgggacg ccgatttcat ggataatgct tgtgatgctc gcgtcgagat ttttcttctt 2383981 tggttcaggc tggctgctgc gtataatact gctttgcgat gatggcgcac gatgcgtcac 2384041 actgctggca tttccgctga cctggcggat atggccgaca aggttttcca tatcaaacgg 2384101 tttgagaata aagtaggacg cgcctaaatc gacggccttt ttcgtgacat cttcctgccc 2384161 aaaggctgtc agcataatga cattcggctg ttttttcaga tctgattccc tcagcctctc 2384221 taaaaccgca agtccgtcta gatgcggcat aataatatct aatacgagca catcgggatc 2384281 tttttcttta aacagcgaca ggcattcctg tccgttataa gcaacgccga tcacttccat 2384341 gtcttcctgt ccttctatat attcacttaa caggcttacc agctctcgat tatcatcagc 2384401 aacacaaact ttaattttct ccacgtttct tcctccccaa atgtagttaa caggattcac 2384461 ccttgctaca tgtttacatt cgacaaaacc gctatatacc ctctaaaaaa atcataatca 2384521 ccaatattag tggcatatct ttgttattct atgtttttct ctgtttttcg actaaaaatg 2384581 aaatttgaca aacaaggaaa cgtgaatttg tcgaaaaatc ttcttttgta tattttaccg 2384641 tatgtattct gagaagtgaa gagggatcaa aataaaaaaa ctgccggaaa ctccggcagt 2384701 cagcttgctt tttcttttcc ataaatatcg attcctgctt ctgacagcat ccattcaata 2384761 tgaacaccgt agccgcttgt cgggtcattt acaaatacat gggtgacagc accgatcact 2384821 tttccatttt gaatgatcgg gcttccgctc atcccctgta cgatgcctcc tgtttctttc 2384881 aacagtcttg gatcggtaat tttcaacacc attccttttg tcgcagggaa tttttgcggc 2384941 gttgtgctga cgatttcaat atcgaatttt tctactttgt catcatcaat aaccgttaaa 2385001 atttcagccg gccctttttt gacttcggta gaaaacgcaa ccggcaatgc ttgatctgat 2385061 atgttgtttt gaatcggctg atgcagtgtg ccgaaaatcc caaacgggct gtttctgtta 2385121 atatccccga tcgttttgcg ttctgaggaa aatcgcgcca gtttttctcc cggattaccg 2385181 cctgtccctt tttcaattga tgttacagtg gatttaacga tttctccatt ctccactaca 2385241 attggtttct ttgtgtccat atcggaaatc acgtggccaa gtgctccgta tttttttgtt 2385301 ttcggttcat aaaaggtcat agtgccgatg ccagcagcag aatctctgat atataacccg 2385361 attctgtatt tgccttctcc ttcatccttt tctgggatca gcttcgtttt gattttctgt 2385421 ttatcacgtt tgatcagtaa gtctaaagat tcaccagttt tcccagcctt ttgaataaat 2385481 ggggctacat cattcatttt ttcaattttc tgtccattca tctcaataat gatgtcgccc 2385541 gcttcaattc ctgccgtttc tcccggagat tttttgcctt cacttgtatt gatttgatga 2385601 aatccgacga caagaacacc gacggaatga agttttacac cgattgattg tccgccaggt 2385661 ataactttta aatcaggaag aacatgcact tttgtttttt taattggaaa tccggcaaga 2385721 tcatatacca attctgactc acctgatttt ttgcccgtca ccttgatttc atgcggatct 2385781 ttctttactg taaacgcttc tgaggattct gatgtctgag cgtttaccga taaactcgtt 2385841 tcaatcgctt gtgtttgggt ttcaaatact ctcatttgcg ttggaatcag taaatattct 2385901 tttagcggtt tgcataaacc tacacttaat aacgaaacaa ggagaattaa acctactgct 2385961 tttctgatgt tatcgggcat tcactacttc actctcctcg ctcctatccc acaccttctt 2386021 tatgacttgc tgctacatca tttaattttg ccttctgacg gcttatttat aactgtcata 2386081 tgaagaaaaa cattggatat actgatgaac gaatggatgt gcacgaaaaa aataagctgc 2386141 gcttctcgcg cagcttaccc agttgttttg acttgatccg cttgttttaa aagttctttc 2386201 gcatggcgtt tcgttaagtc ggttacttcg acacctgcaa tcatgcgccc gatttccgct 2386261 accttttcct gcttagagag cggcttgaca cgtgtcgtcg ttctgccgtc ttttaactcc 2386321 ttcgcaatat aaagatgcgt atcggccatg gcagccacct gaggcaggtg tgtaatgcac 2386381 agcacttgtg atcctattga caccttatgg atcttctcag caattgcctg tgcgaccctg 2386441 ccgcttacac cggtatcaac ctcgtcaaaa atgatcgatg tcacatcctg ttgtgaggaa 2386501 aaaatgcttt ttatggcaag catcacccgt gacagctctc cacctgaagc gactttcgaa 2386561 agggatttca gcggctcgcc tgtattggtt gaaattaaaa acttcaccag gtcaatccct 2386621 tgttcagtca gctgaacggg ctggccgttt acaagcggcg cctcttcatt gcgtgacgct 2386681 gttctgacct taaattccgt atcaaaagtt gatttttcca tgtacaggct ttttaattcc 2386741 cgatgaatct catcagccag ctttttcgcc catgtttttc ggatttgtga cacatttgcc 2386801 gcttccactg cgacatcttt gccgacggag tcaagctcct ttttcaagct ttgaaggtgg 2386861 ctgtccctgt tttcaatttg gtcaatctct tcttcaattt tagaagcata ttccaaaatg 2386921 tcttcaacag tggcaccgta ttttcgtttc agctgtttga tttcattaag tcgcgtctca 2386981 atatagttca ggcgttccgg atcaaattca agctcatcca gcatatttct catctgaaat 2387041 gtggcatcct caagcaaata gtaggagttc gaaacacttt cagacatttt tttcagcggt 2387101 tcgtttatat cagatatatc ttcaagctgc gctgatgcca ttccaaccca gtccaatccg 2387161 ccctgctcac tgcgaagcgc gttatatgca ttttgcagcg actcatatat cttctcaaag 2387221 tttgaaattt gctggcgctc ttcttggagc tgttcatctt cgttaagctc aagctttgcc 2387281 gattcgattt cttcgagctg aaattgaata agatcaagac gatgggccat ttcctgttcg 2387341 ctttcagaaa gctgcttaag ctttttgagc agcttcacat accgctggta cccttcctga 2387401 tacgttttga gcgcgctttc cacttcggcc ccggcaaact tgtccaaaag ctggagatga 2387461 ttttcgtctt ccattaacag ctggttatcg tgctgcccgt gaatatctaa taaaagcctg 2387521 ccgatctctc ttagtgaagc aatcgtgaca agcttgccat tgacacggca aacgcttttc 2387581 ccgctcgtgc tgatatccct tctcatgacg atcatttcgt ctgaaacgtc gattccctgc 2387641 tcagcgcata cgcctaaaac aggatggccg ctctccaaca gaaacagccc ttcaagttcg 2387701 gcttttgctt ccccatatct aacaaattca gatgatccgc ggcctccgac taaaagagaa 2387761 atggcatcta tgatgatgga tttgccggct ccggtttctc ctgttaaaac cgtaagcccg 2387821 cgttcaaaag aaaccgtcag ttcctcaata atggcaaagt ttttaatcga tagttcagct 2387881 aacaaacagc attacacctc ttatctttgt tagattttct gttacagcag ttcaaggagc 2387941 ctgtttttta cgccttctgt atcttcagga gtccggcaaa taattaaaat cgtatcatct 2388001 ccgcaaatgg tccccatcat ttcatcccag tccaaattgt ccatcagcgc cccgattgcc 2388061 tgggcattgc ccggcatcgt tttcagcaca atcatatggc ttgctgagtc tattttcaca 2388121 aatgcgtcca tcaatgcccg ctttagcttt gacagcggat tgaaacgctg gtccgccgga 2388181 agactgtatt tgtaagaacc attatttgta ggcactttta caaggtgaag ttctttaata 2388241 tcccgtgata ccgtggcctg cgttactttg tatccatcct gctttagcat gtcgaccaat 2388301 tcatcctgcg tttcgatttc attgcttgta atgatctctc tgattttaat atgcctctgg 2388361 cctttgttca tgtaagcacc tctatttcca agcttatctg ttcttttatg ttatatgatt 2388421 ctctgcacat tgtacatgaa tgcagaaaaa aggaataata gcgccctatt attccggtac 2388481 atctgctttt ttttctttta acgtcttatg tgcttcttct acaacgcgca tgatctcttc 2388541 ttccggcagt tcctggcctt cctgtccctc tcccggccaa tgcaaatgaa ggagaaactc 2388601 aatatttccg tctcctcccg tgattggaga aaatgacaag cctttacaga tatagccttc 2388661 agcggcagaa aaactgatca ttcgcttgag cacatcagca tgcactttag gatctctaac 2388721 aatccctttt ttgccgacgg attcccgtcc cgcttcaaac tgaggcttaa ctaaagccat 2388781 gcagtcgctg cccggtacga gcaaagtcct taggacaggc aggatgagcc gcagtgaaat 2388841 aaaggacaca tcaattgtgg caaactccgg catgcccttt gtaaagtctg ccggtgttgc 2388901 ataacgaaag ttcgtccgtt ccatcacgac gacccgttca tcctgtctaa gcttccatgc 2388961 aagctgatta tagcctacat ccacagcgta tgactgttta gctccatttt gcaaagcgca 2389021 gtccgtaaaa ccgccggtgg aggagccaat atcaatcata attttatctt tgacagagac 2389081 gggaaattcc ttcaacgctt tttcgagctt taagccgccc ctgctcacat acctcagcgg 2389141 gtttcctttg acagttaacg gaaggtcgcg gtcaattttt tctccaggct tgtccaagcg 2389201 gttttcgttt gaatagacga tccccgccat aatggctctt ttggcttttt cacgcgtttc 2389261 cgccagccct ctttccacta ataatacatc taatcgttct ttctttgacg tcatgatcca 2389321 attcctttgt gtgtctttgg tggcatcagt aatctaatac gatttgccac ctgctgtttt 2389381 gtcagtccaa tttcctcaag aagcgctgtt acacttccgt gttcaataaa ccgatcaggt 2389441 atacccattc tgtcaatcgg agtatgatat tcaccttgat catgagcgaa ttctaaaatc 2389501 gagcttccga aaccgccttc taagaccgct tcttcaattg ttaaaattgg caagccttct 2389561 tttaggatac tcttcatcat cttttcatca atcggcttaa taaaacgcgc attcacaacg 2389621 cgcacggaaa ggccttcttt ctgcagctct tcggctgctt caatcgccat ttcgattgtt 2389681 gtgccgaatg ttaagatgac agcatcgttc cctggacgca gcacctccca cgtaccgatc 2389741 ggaatcgttt tcaactgttc atccattttt acgccgagtc cgtttccgcg cggaaaacgc 2389801 attgctatcg ggccttcgtc atagctaagt gctgtatgaa ccatgtgctg gccttcattt 2389861 tcgtctttcg gcatcattaa gaccatgttt ggaatgtggc gcataaacgc aatatcaaac 2389921 acgccttgat gtgtctctcc atcagcgcca acgagtccag cacggtcaat tccaataaac 2389981 acattagcgt tttggcggca gatgtcatga acaacttggt catatgccct ttgcaggaag 2390041 gttgagtaaa tcgccaaaaa cggcttcata ccctgcattg ccatagctgc agccattgtt 2390101 gcggcatgct gttctgcgat tcctacgtcg aacatccggt cagggaattc ctttgcgaag 2390161 ccttcaagct ttgaaccgac aggcatagcc ggcgtaatgg ctacaatgcg tccgtcctcg 2390221 cgcgccattc gctgcacagt tccgctgaca agaccgctcc acgaaggagc tgcggctttc 2390281 ggctttacaa agtcaccggt attaatttta tatggtccgg taccatgcca tgtcccaatc 2390341 gtatcggtct cagccggttt gtaccccttc ccttttttcg taatgacgtg cagaagaaca 2390401 gggcctttcg tttttttggc gtattgaaga ttctcaatca gctcatgata agaatgtccg 2390461 tccactgggc ccaaatacgt aaaaccgagc tcctcgaaaa acattccgga gacgagcatg 2390521 tatttcaggc tgtctttgac ccgttccgcc gtggcggcaa gcttgccccc aactgccgga 2390581 atctttttaa ataagtattc aagctcatct ttgacccact ggtatttccc cgcagtgcgg 2390641 agccgtccga gcatagagtg aatggcaccg acgtttggcg caatactcat ttcattatca 2390701 ttaaggatga caatcatgtc ttttttctcg tcgccgatgt ggttaagggc ttcgagcgcc 2390761 ataccgccgg tcagcgcgcc gtcaccaatg atcggaataa tatattcatc cgttccttta 2390821 atatcacggg cagctgccat tcccatcgcg cctgacagag aagtcgagct gtgcccggtt 2390881 tcccaaacat cgtgctcgct ttcactccgc tttggaaatc cgcaaagccc tttgtactgg 2390941 cgaagcgtcg caaattcttt tccgcgtcct gtcagcagct tatggacata cgactgatgg 2391001 cctacatccc ataaaaattt gtctttcggg ctgttaaatt ccttatgcag ggcaacagta 2391061 agctctacga cacctaagtt tgggccgatg tggccgccgg aagcggataa acttgtaatt 2391121 aaaaactgac ggatttcatc acttaatttc tctaattcat caatggacat gttttttaaa 2391181 aacgacgggt cctgtattga taaaagatcc aaagcggatc aactcacttt cagcatgaat 2391241 ttctgcaatg atacatgtct tttgcatgcc gagctgacaa taatctcaga cataaaaaaa 2391301 gacaaacgcg cttttccttt tcatttttca tataaactgc ttacatttta ccatacctcg 2391361 tgcagccgct tcaaattagg atcgttttag tgatctcttg ccgcaattaa atcacaaagc 2391421 tcatataaaa ggtctttttg aagagagagt ccgccgatca atcgcttcgc ctcttttata 2391481 tgaacatcca atttatgttt ggccccttcc aatgaaagaa gcgacgggta tgtcgatttg 2391541 tcatttgtgg tatccgagcc gacacgtttg ccgattttct cttcactgcc ttctaaatct 2391601 aaaatatcgt ctctgatttg aaatccgatt ccaatgtggc tgctgaaggt acgcagtgtt 2391661 tcaatgtctt cctcaggcgc atcagccaaa atagcaccgg cgattacaca aaagccaagg 2391721 agcttggcag ttttccgttc atgaatggat tcgagctctt caagcgtgac ttgtcggttt 2391781 tccgcttcca tatcagctac ttgcccaccg accatgcctt cggtgcctgc cgctgaaatc 2391841 agttcattca caagccgcag gcgcttttct gctgacacct cgtctgacac gtgggaggta 2391901 atcagcttaa agctttctgt gagcagcccg tcacccgcta atactgccgt cgcttcacca 2391961 aacactttat ggtttgtcgg cttcccgcgg cgcaaatcgt catcatccat gcatggaaga 2392021 tcatcatgaa ttaacgaata cgtgtgaatc atttcgacag cacagcccac cggaatgccg 2392081 tctttttcgc tttttccata tgcatttaaa acagccagta caatcagagg ccgcaaccgc 2392141 tttccgccgg cctgtagaga atatagcata gatttcttta atgagtccgg catatcaagc 2392201 ttttctgtat agacagaaag ctgattttca attgtttttt tccggtccgc cagaaagctc 2392261 gttaatttat ttgtcacctt cgtcttcctc ctgaacactg aaaggtgcca gttcgccgtc 2392321 ttcttttaaa atgaagtcca tttgcttttc gactttttgc agcttttcat ggcacatttt 2392381 tgacagagcc atgccttctt ggaaatagtt aatggcttgc tctagaggca catctccctc 2392441 ttcaagcttt gatacaatgc tctcaagccc tttcatcgct tcttcaaatg tcatgttttc 2392501 attttttttc acgtctgtca tttttcttcc cctctctttt ctaatacttc acaggtcagc 2392561 acgccatcct tcagcttgat ttcaagccgg tcctgctctt ctatttgact gacactttta 2392621 atgagtttat cttctttata agccaagctg tatcctcttt ccatcacttg aagaggactt 2392681 agtgcattca gcttgccaag aacggtttga aattgggaat gcagctgctt catttggata 2392741 ttcatatttt ttctcagctg atttgtttgt tcctggtatc gtgttctcgc ttgtttcagc 2392801 tgttcatgag gatgcaatgc ctctaatctg tacgtttcac gctccagctg tctgcttttc 2392861 cgatctaaaa gagcggtcag ctgtgcttga aactgctggt acgcgaggtc aaactgctgc 2392921 tctttttgcg catacaaacg ctttggaaaa cgaaaggcat aggacgattg cagcgtttgt 2392981 atccgttctt ttttctggcc gagatgctgc tgcattgctc ttgtcattct gacttccgct 2393041 gtttttgtcc gttcgattaa atcagtggta tgaggcacag caatctcagc tgctcctgtc 2393101 ggcgtcgcag ctctgatatc ggcgacaaaa tcactaatcg taaaatccgt ctcatgtccg 2393161 actgccgata taatcggaat attggaagca aagatggcgc gtgctacaat ttcttcattg 2393221 aatgcccaca gttcttctat cgaaccgccg cctctcccga caattaatac gtcgcaaatc 2393281 tctttttcat ttgcctcttc aatgcgcgta acgatggatc tgctcgcatt ttcaccttgt 2393341 acgagcgctg gaagaacaat gacttttaca aggggatatc ttctttttag agttgtaata 2393401 acgtctctga cagcggcacc cgttggagat gtcacaaccc cgattgtggc tggaaatgcg 2393461 gggatttgtt ttttgtagcg gtcgtcaaat aaaccttctc cggcaagctt cttttttaat 2393521 tcttcgtacg ctaaataaag cgctccaacc ccgtcaggct gcatttcttt ggcatataat 2393581 tgatagtttc cgctcggttc atatacggaa attccgcctc tgaccagcac tttcattccg 2393641 ttttcaggtt taaaaggcag acgctcgctt tgtctcgcga acatcaccga ctgcattctt 2393701 gcgttttcgt cttttaaagt gaaataaata tgccctcgtg tgtgtatctt tacattcgac 2393761 aattcgcctt taatccaaat attttcaagg tgaggatcta catcgaattt tcgttttata 2393821 tactttgtca gcgctgagac ggtcacatac gctgcttcac ccatgtctaa aaactcctct 2393881 cctaagcatt cctgcaccat aactaaagaa aacccgccct ggctttagga gcctgaagaa 2393941 gcgggtatcg tgctcatatt caaggcgggt aaacatttcg cctgtgaata tctccaatta 2394001 tctatgataa cgtacgtttc gcagatttaa cagtattatg cgcaagcatc gtgatggtca 2394061 tcggacctac tccgcccgga accggcgtta tgaaggacgc tttttccttt gccccttcaa 2394121 attcaacgtc tccgcaaagc tttccgtttt ccagacggtt aacgccgacg tcaatgacaa 2394181 cagcgccctc tttgatctgg tctgcactga tgaagttggc tctgccgact gccaccacca 2394241 ggatgtccgc ttttttcgta tgttcagtaa tattttctgt tcttgaatga cagtaagtaa 2394301 ccgtcgcgtt ttcatttaat aaaagctggc cgacaggttt gccgacaatg ttgcttcggc 2394361 cgactacaac aacctcttta ccggaaaggt caatattggt tttcttcaaa agctcaacaa 2394421 ttccatgagg cgtgcaagga agaaacgtat cttcgccaag cagcattttc cctacgttta 2394481 acggatgaaa accgtctaca tctttatcag gggagatacg ttcgatcacc gctttttcag 2394541 aaatatggtc tgggagcgga agctgaacga gaatgccatg aaactcaggg tcttggttat 2394601 attgatcaat aatggaaagc agttcagctt ctgtgaggct gctgtcaaat tgatcgagct 2394661 tgaaattcat tcccattgtt tctgccgctt ttttctttcc tcgcacgtaa gagtgagaag 2394721 caggatcatc tccaatcaaa ataaccgcca gtccgggagt gacgccttgc tttttaagct 2394781 cttctacctc ttttgccaat tgttcgcgtt tttctctagc cgtttctttt ccgtcgatga 2394841 ttgttgcagt cattttcttt cctcctatga ttgttcaata tcagatttaa tgttagaaag 2394901 aaccccgttt acaaactttg tcgctttgtc atcaccaaac cgttttgcca gctcaatcgc 2394961 ttcgttcatg gagacattca ccggaatgtc ttcggcatat gccatttcat atgctgccag 2395021 gcgcaaaatc gcacggtcaa cattggcaat ccgatcgagc ttccaattca ccagatgctt 2395081 ggagatcatt tcatccagct ggtcttggtg ttccaatacc ccgtgtacaa gctgttcaaa 2395141 gaaaggatct gttttttctt catccagtgc gtgttctatg gcttcattca ctgcaatatc 2395201 gctgacatca atttgaaata gtgcctgcaa agctttttct cttgctgttc ttcttttcat 2395261 tttctttctc ctttgatcct ctttatccgc ttgtcgttaa gccacaaaga gatcataaca 2395321 tatttttttc gtatccgcat attgaaatca aggttttttt accctattac cgaatatttt 2395381 cacacacctt aatatgatta ttcggatttc acgttcatga agaaactcgg ctatgtaagc 2395441 cggctttctt catgctttga aataaagggt aacgtgtaaa aaaaccaaag ggccgccctc 2395501 cccttggttt cgtgttaagc catttacatt tcttcgtcga tttggacttc ttgggctttt 2395561 gtgtcaaatt gaatgccgac gatgtgaata ttgatctcgt taatcgaaag agacgtcata 2395621 tttaataagg tttgacgaat gttttcctga acggatgctg caactttcgg aatcgaaacg 2395681 ccaaatgtaa cgacacagta tacatcgatc gtaattccgt catccgccag gtcgactttg 2395741 acacctttgc catgattcac tttgccaaag cgctcaacga cgcctgtcgc aaagtttccg 2395801 cgcatttcgg caactccatc aacttctgat gctgcaatgc cggcaatgac ctcaatgacc 2395861 tccggtgcaa tctcaacctt acccaaatgc gtatcttcgt gatccatttt aagcaagctg 2395921 ttgtctttca ttcaattcac ctccgtaaaa attatgagcc cattacatca tatgtttcta 2395981 aaaatttcgt attaaactct ccgctcacaa atgtttcgtg ttcaagcagt tttaaatgga 2396041 aagggattgt tgtctcaatg ccttcgatga cgaattcgct caatgcgcgc ttcatgcggg 2396101 caatcgcttc atctctcgtt tttccgtatg tgattacctt tgcaatcatg ctgtcatagt 2396161 acggtgggat ggaatagcca gggtacgcag ctgaatcgac acggacacca agaccgccag 2396221 gaggcaggta cattttaatt tcaccaggtg acggcatgaa atttttgctt gggttttctg 2396281 cgttgattcg gcattcgatg gcccagcctt caaattcaac atcttcttgc ttgaggctca 2396341 gttccattcc tgaagccact ttgatttgtt ccttgatcag gtcagttccc gtcaccattt 2396401 ctgtgactgg gtgctccacc tggattctcg tgttcatttc catgaagtaa tagcgctgtt 2396461 cattgtagtc atagataaat tcaactgttc cagcacctgt atagccaacc gctttggcag 2396521 cctttaccgc tgcatctccc atttgctccc tgatttctga atcaagggca ggagatggtg 2396581 attcttccaa aagcttttgc aggcgtcttt ggatcgagca gtcgcgttcg cccaaatgga 2396641 tcgtatttcc gtagttatca gcaagcactt ggatctcaac gtggcgaaaa tcttctatgt 2396701 atttttcgat gtatacacct ggattcccaa atgcagttgc cgcttcctgc tgtgtaatct 2396761 taatgccatt aatcagttcc tcttcagtgc gggcaaccct aattcctttt ccgcctccgc 2396821 ctgcggtggc ttttataatt acaggatacc caatttcatt agcaagcgaa accgcttctt 2396881 ccacattttc tataattccc tgtgaacccg gtacgattgg cacgccggcc tgtttcatcg 2396941 tttcccgcgc aacgtctttt gttcccattt ttgaaatggc gtcagcgctc gggccgacaa 2397001 acgtgacatt cacttcttca cataattcag cgaaatcagc attttcagct aaaaatccgt 2397061 atcccggatg aatggcgtcc gtgccagtca gctttgcaac actcacaata tttgtaacgt 2397121 ttaaatagct gtcttttgat gctttcggtc cgatacaaaa agcttcatcg gccatttgaa 2397181 catgaagggc atctttatca gcttctgaat aaacagcgac agtctcaatt ccgagctctc 2397241 tgcaggctct gatgattctg acagcaattt ctcctctgtt ggcgatcaat agctttttaa 2397301 tcatgttcag tctccttact ccgcttttac aagaaataga ggttgtccgt attcgaccag 2397361 ctggccgttt tctactaata cttcaacgat ttcgcctttc acttctgctt cgatttcgtt 2397421 gaaaagcttc atcgcttcta caatgcagac aactgtgttt tcatttactt ttgaaccggc 2397481 tgttacatac gggccagctt ccggtgatga agaagcataa aatgttccta ccattggtga 2397541 agtgatttta tgcagattct catcttgctt tggtgcttct tgggcaggtg ccgctgcttg 2397601 ctgcgcttgc ggctgaactg cctgcggagc ctgtgcttgt acaggtgctg ccggtgcctg 2397661 ctgcatgact tgaaccgtgc ctgcttcgtg ttttttcagt tttaaggata caccttcatt 2397721 ttcatatacg aattcgtcaa ttgtagactc gtcaattgct ttaatcagct cgtggatttc 2397781 tttgatattt aacattcaat cgcactccta tgtatgaaat ttcttttttt ataggttact 2397841 actaaaagta catactatgt tcatcttaca ggagcggact tttgaattca actctaatat 2397901 gacagcaacg caaaaagccc gcttgtttag cgggcttttt tccctcattc ttatttagag 2397961 ggttcaaatg tgacagcgac atctttcatt gttttgattt cttttgccac aaggtctata 2398021 atggctgtcg ccttcgattt agagtgtttg tctgatttga ctgtaatatt gattttatct 2398081 ccttcagcat taacaagcgc atcctcgtaa ccttgtgttt taatcagcgt ttccagctgt 2398141 ttttctgttc cttccacttc actgagagcc gtcattttat cgtatgcttc gcttttctcc 2398201 ttggctgttg catcatcgct tgacacaatg gcattcagct cttctctttc tttgcttctg 2398261 gcatcttcta aatcaagacg gtacgttgta aacaaatcat catcggctgt ttccgtaaca 2398321 acagttcctt tttcactggc ttcagcggat gtttccttgt ctgctgatga atctttcgtt 2398381 ccctttgttc catcttcttt tcctttttca gtttctgtac cgcttttttc cttcgtgtct 2398441 tgcttggcag gcgctttttc agttgcgacc tctccgctgt cagacgcgct tttttcactt 2398501 tgcatctgca cggcgttttt gctttccggc gacatgatat agtagacgct taacaccacg 2398561 acaagactga gcattgttaa tagccaaacg gtttgttttt taagcattta tgaatcctcc 2398621 tttatttttt taggggcaac cgcaacccgg tggcttggaa catccaggac ccgtgtcacc 2398681 gcttcgataa tggtttgttt tatttgaacg ttgtccactc cttgagcaac aacgagtaca 2398741 ccgcgtatat caggtttttt cgtttggacg acgacaggtg tttctttatc gccgtttttg 2398801 atcatgacga tttcttcctc cgatgattgg tctgtaacgc ttctttttcc gccttctttg 2398861 tcagtttctt cagtggttgt atttttgttt gatttgtttt tttcgtatac tttcagcgac 2398921 gttgcatcta cattcacgac aaccgagaca tcgtccacac caatgattgt ttcaagaatt 2398981 tctttcagtt gattttcgta ttctttttca tagtcatcga tcgagtcttt aggtttatca 2399041 gattttgagg ctttaaacac ttcggctgtt ttctctttgc tgtctgcgga atgttgtgat 2399101 gatacggccg ttatcgtttt ggcgttttca gttttctcag gtgaagaaaa cagctggctg 2399161 acaagcataa aggaaactcc gagaacaaaa acgaatagaa agtaatgata tttggtcagc 2399221 ttcggctttt cgccgtcctt cgtttgtccc ggaagaaact gctttttcaa tacattccat 2399281 aatccgtttt tattcattgc cgacactctc cccgccttcc atatgaaccg taattttctc 2399341 acttccgatt tcccaaatgt ccgcgagctg cgtttgtatc tgtttggctt ctttttgttc 2399401 ggctgcttct tttgttacgt atgcatgatc tgtatcaatg tggaccggcg cgaccgtttg 2399461 gaccgttttt tcagaagacg gggccatata cacgctgatt gttttaatat cctcttctga 2399521 atctaccttt tctcctgccg tgagtttgat gcggcctact ttatattcat catgactgaa 2399581 tctctcctcc gctttctttt ttagttggac agccatttct tctagaatat atgcgcgctg 2399641 ggaagcttgt atttctattt tttttgaatt gatttgattt tttatgtcgg cagactctga 2399701 ctgcccgttt tttgtgaggt attcaaagat gacttcgggg tctgtcttga aaagtttaaa 2399761 aatcggcgta agcatgacga caatcaagag caggctgact accatttttg cgtacttttg 2399821 catgctggag ctcggcagca gcatatcaat cacaattgca aataggataa acaacacgat 2399881 ggtggtaagc cattccgtta aaaaactcat ttgcctgcct ccttcatttc atcatcatcg 2399941 tgaggtttcc ggctgtgatt atgacagtaa ggcttaaaaa aaacatgaga gacacaatgg 2400001 cgagagctgc aaaaatataa atgacgcttt tgctgatgac gtcgaggcag gtgatgacgg 2400061 gcccgcctcc tagcggctga agaatcgcgg ctgccagctt ataaataaaa gcgagggaaa 2400121 gcactttgat tgccggaaat gccgcaatac agatcaaaat agcgacaccg agaatcccta 2400181 ccgtattttt cagcagtaaa gaggcgctga ttactgtatc tgttgcgtct gtaaacattc 2400241 ggccaagcac aggaataaaa tttccggtta taaatttagc cgtcctgagc gtaatgccgt 2400301 ctgtcactgc agctgacgct ccctgaacag agatgacgcc gagaaagatg gtaagaaaaa 2400361 cagccagtgc tccgatggcg atatttctga gcaggttagc cagctgcgtt actttgtatt 2400421 gttcagtcat cgtgctgaca atgctcagaa tcgctgataa aaaaatcagc ggcatgacga 2400481 tattctgaat caagagaccg ctcgtgttca tcaggaagag gataacagga tgaaagaagg 2400541 cagcagatac agctccgcct gaggaagcca aaagcgccaa gaggagcgga atgagcgcca 2400601 ggataaagct ggtcatcgtc tgaatcgcct cagttgcata gttaattgcc acatgaaagc 2400661 tattaagcgc aaggataatc agcaccatgt acacaattga gtaagcgacc ttactgacgg 2400721 tgctttgctg aaaagcattt tgcaaaagct gcagaatgac gcaaaaaatc gtgagcaaaa 2400781 tcaatgtgcc cagcagcttt ccgttggcaa gcacttcatg aaacaaataa gaaaagagag 2400841 ctttcagcca ttcttgcggt gagaatgatt tatcgccatt gataaactcc attaagctgc 2400901 ctttttggct ttccggcagc agtccgccgt attctgtcat aatgtcattc caaaattccc 2400961 cgatcttatc tgtttcaagc gaggctgctg tcctttccgc taattgctcg gctgtttcag 2401021 catggtcttc cgtttgttct gcattaccag ctgcttgtac aatttctgca cggcctgcta 2401081 tgatcagcac ggccaaaagc aaaacccatt gaaagcgctt caatctaccg cctcctttcg 2401141 gttatgacat agaaggtata agtccgagaa tcgtttcgat aatgacggtt aaaataggca 2401201 cagccattac gagtattaaa attttccccg ccaattctat tttcgaggcg atggctcctt 2401261 gaccggcatc ttttgtgagc tgtgccccga attcagcaat ataggcgatt ccgataatct 2401321 ttaaaatggt ttcaacatag accatgttga catttgcatt aatcgcaatt ttttctatca 2401381 ttcgaataat gtcgtagatt tggtctacca aataaagaaa aatggcacat ccggcaaaaa 2401441 cgacgattaa aaacgcaaaa gtcggctttt gttcttttac aattaaagaa aggaaggtgg 2401501 cgatcagccc taaacctaca atttgaacaa tgtcaatctg caagcccccc tatccttgga 2401561 ataaaaacac agcttttatc tttttaaata ggtcatctac aatcgtggcg accataaata 2401621 aaatatagat aaaacctaac agcgtcaccc actgagcata ttctttcttg cccatctgat 2401681 ccaatatcgt gtgtaaaaaa gcgaccacga ttcccactcc ggcgatttga aatatgacat 2401741 tcacgtctac tcccatttta tttttgctcc cctcacgttt acatcaatag aagaatgagt 2401801 aacaagcccg ctaaaaagcc caaacttttt atcatctttt cgtttttcgc ttgcgcctgc 2401861 tcagcatccg cttctgaggc ttccaaatgt gtcagcgcca gcttgatgtg cttttgctga 2401921 gagattcgat catgaatccc aagcgtctcg ccaaactgct tcagcacttc gtattcgctt 2401981 tttttcaaag acagggtgtc ccataccttc tttaagcttt gctcccacgc cgttttcgcg 2402041 gaatcacttc ccttgtccag ctgatcactg aatgcggaaa aaagagttga aacaggctgt 2402101 gcgagctgtt tggcaatctg ctgtgaagca gtatgaagcg gtgtatggcc gtacatgatt 2402161 tcagcctcga gggattgaag cgccgcacgc agctggcgga tttgccgcgg ccgttctgta 2402221 taaatcttcg ccatctcaaa acctgtccat gttgtcgcta ccacaatgaa tacagcgccc 2402281 agcagcttca gcatgttttc acgcccgtcg tcctagacag cacatttccg tctttgtcat 2402341 aaatttggct cactgtgccc ggcccttttg ctcttgataa ttccaaatag cggtcaaagg 2402401 ctctttcttc ccacaaacgc ttcaatgaag gccgcttcat caggtcggat atactccagc 2402461 catgcgccga tacgattact gaaacaccgg catgcagcgc ctccagaagt gcatctgtat 2402521 cttccatacg cccgatttca tcgacaatca tcacctcagg gctcatggat cgaatcatca 2402581 tcatcagccc ttcagctttt ggacaggcgt ctaacacgtc aattctctga ccaaattgat 2402641 gctgcggaat accgcgaaga catccggcaa tctctgaccg ttcatcgacg atccctgtct 2402701 ttacgggcag catgtttttt ttgccggtgc ttgagagcct cgcaaggtcc cggagaagtg 2402761 ttgttttgcc ggtttggggc ggtccgataa tcagcgtatt cagccagctg ttttgatata 2402821 agtatggaag cagcggctcc gcaatcccca gcttttgccg ggcaattcgt atattaaaag 2402881 atgcgatgtc acggaggcct ttcacacctc cgttttccgt aatgactctg cccgccagtc 2402941 cgactctgtg gccgcctctg atcgtgacat accctttctt cagctcttct tcaagtgtat 2403001 acatactata gttgctgagc cggctcagga tcagatgggc atcctcggcc gtgcccgcat 2403061 aggacaaata aacaggttgt cctcttcgaa tcaattcaac agggcggttg atccgaattc 2403121 tgacttcttc gatttccagc cattgttgtt ccggtatttc agaaagggcg tttttcatgg 2403181 attcagggag aacctcagcg atttcattca acagagcctc ctcctttcta ccgattggct 2403241 tctttaaaat gtatgatgtg aggcagactt tatgacaagc ctctctttat ttatgaacac 2403301 ccgccaaaat caagacaaca cccgtaaaaa tcagaatcag ctttgcatac gaaagctgcc 2403361 cggcaatttg gtagattccg acagtcattg taatgataaa aatcaacgga ccgacaatag 2403421 cgagaatgct gttaaccaca accgccttcc ggacatcgtt ggtcacaagc atgacaattg 2403481 ctgccgtcag ctcaatcata gaggataaaa ctcgtaatcc cgccattgtt aaaacagtag 2403541 aattgatatt tccaagtaaa aatttcatag cactctccca acctcccatt tttttatatg 2403601 atatgctcta gcttgctgaa gtagtcttgt cattttcgta taaaagaaag attctgtttt 2403661 tgggcacaaa aaaagcctgc tcccatttgg gaacagactt ctttttttct ttctatgctc 2403721 ttgaaacgta agaaccgtct gatgtattga caacaagtgt gtcgccttca ttcacaaaga 2403781 acggcacgtt tacaacaagc ccggtttcag ttttcgcagg ttttgtaccg cctgacgctg 2403841 tatcaccttt aataccaggt tcagtttcaa caactttcag ctcaactgtg tttggaagtt 2403901 cgataccaag tgtttcatcc tggtacatca tgatatgcac agacatgttt tctagcaggt 2403961 attttaattc ttcttcgatt tgagttgcgc tcagttcaag ctgctcataa gaagaagtat 2404021 ccataaatac gtgctgatct ccgtttgcat atagatattg cattgttttg gtttcgattt 2404081 gcgctttcgc tactttttca ccagcgcgga atgttttttc ctgaatcgcg ccagtgcgaa 2404141 ggttgcggag tttagagcgg acaaatgccg caccttttcc aggttttacg tgctggaagt 2404201 caacgacgcg ccaaatgccg ccatctactt caattgttaa tcctgtacgg aaatcgttaa 2404261 ctgaaatcat gtttaatgtc ctcctatatt ccaatcacaa aataataagt tcttttgggg 2404321 aatgggtgat tgtccggttg ccgttttctg taatcacgat gtcatcttca atgcggacac 2404381 cgcctgtttc tggtatgtaa atgcccggct ccactgtgac caccataccc ggttcaagga 2404441 tagctgaaga tctgacggat aatcccggcg attcatgaac ttccatgccg agcccgtgcc 2404501 cggttgaatg gccgaaatag tcaccgtagc cttttgcagc aatatgatcc cttgtgaggg 2404561 cgtcagcctc ttttcctgtc attcccggct taatatgtgc gacgccaagc gcctgagcat 2404621 caaatacaac ctgatagatc tccttcaatt gatcactggg ctgacctaca gcgaccgtcc 2404681 gggtaatatc agaacaatat cctttataat aagcgccaaa atcaagcgta acaaggtctc 2404741 cgctttcaat cagtttgtca ctggccacac cgtgcggaag gcttgaacga aggcctgagg 2404801 cgacaatcat atcaaaagaa gagctgtctg ctccctggct tctcatataa aactccagct 2404861 cattggcaac agcgatttca gaaatgccgg gtttcataaa cgtcaagata tgtctgaagg 2404921 catcatctgc aatcttcgca gcttcctcta atatcttaat ctcttcacta gacttaatca 2404981 agcgcaactt ttccacggat tcagccacag gcactaattc ggcatcactg ataacggcgc 2405041 tgtatgaagc gtaagtgcca tatgtcatgc tgttctgttc aaagccgaga cgcttgatgc 2405101 caaacgattc aacagtgtcg gcagtggtct gaatcaagct gccgccatgt tcaatgatct 2405161 caaaaccctt tacctgaacc ttcgcctgct cagtataacg aaaatccgta ataaacgctg 2405221 ctttgtcacc cgatataaca gccaaacccg ccgaacctgt aaaccctgtc atatagcgta 2405281 cattagtgtt gcttgtaatc agcatgccgt caattcccag ctgtccaaac aggtttctta 2405341 atttctctag cttcatcttg attctccccc ttgctggctt aataagtagc gaacagcaag 2405401 cttgtagcct tcagctccaa gaccgacaat ctgccctttc gcaacaggag cgataaccga 2405461 ctgatgcctg aattcttccc tggcgtataa gtttgataaa tgcacctcta ccacaggaag 2405521 actgatgctt gaaacagcat ccctgatcgc atagctgtaa tgactcaggg cgccggggtt 2405581 cagaacaatc ccgctgtatt gctcctcagc ctcatgtatc gcatctatca aatcaccttc 2405641 gtgattagac tggaagaaag tgagctggat atgtaaggct tcagcaaact gaaaaagatc 2405701 tgtttcaata tcggtcagtg tctggcggcc gaatacttca ggctcacgac tcccaagccg 2405761 gttaacattc ggtccgttca aaatcaaaaa atgaggcaca caatctctcc ttttcgcgag 2405821 ggtttctcat gtaaaaaatg ttcacttctc gtgaacattt tatcatactg gaaaaggatt 2405881 atacactatt ctctatgcat tcccagcgca cgtgcaagct tttccgaatt cagctcattg 2405941 tattcaaatg aaatagaata cccgacaaac agcccgtaaa gcaaataaat gcaaatggtc 2406001 gtaataattg tatctgatgt cagttcggtc accgtgcgca catctggaaa aatcggatta 2406061 aaaacaaaaa acacgagcag ccaaagcacc aagccgtata aaatacccgg ccacattgtt 2406121 tttaaacgtt tcaatagaag aaaataaaga aatgctgcgc caattgaaat tactccaatc 2406181 aaaatgatgc tgattaccgt tcccagccca tgttttttcc actctccgag tacaaacggc 2406241 tgcaatatca tattcgggct gatttcggaa aaatgaaaca aatatgcgat ataagcaacg 2406301 aaactccaaa gtacgcctcc gcaaaaacct gttgccgcca ccctgccggc cattgaaaca 2406361 ggcggctttt gcttctcatt caattcttca ttttgttctg tatctttttc gcttgtcatc 2406421 atggcacctc cagttaaagt gtgcccaaaa aatgaaatgt caataaaaaa gctcacactt 2406481 tttggcagct gcgagtaaaa tttgaaaata acgggtataa tgcatgtaga aaaagcaagg 2406541 ctatggcaat tttttcagcc tgtcaatcta gaggtttagc gctgtttcct gtacaataga 2406601 gtgaaaggaa atggttagca atcctaaaga aataggcagg ttgataatat gtcaaaacat 2406661 aaagttccgc ccgcttacgg cgggcaggct gttgtggaag gcgttatgtt tggcggaaag 2406721 catcattacg ttacagccat cagaagaacg gatggaagca ttgacttttt taagcttcca 2406781 cgcaaacaca acccgaaact gaacatcgtg aaaaagatac cgtttttacg ggggatcgcg 2406841 gccattatcg aagcgagtgc aaacggcaca aagcatttga atttttcaag cgaacgttac 2406901 gggctcgatc catctgaaga cgagacactt gagcaggaag aaaaaaaatc ctctgggctg 2406961 tctatgtatc tcagcctcgc agttataggc gtcctatcat ttttgttcag taaattcgta 2407021 tttacattgg ttccagtttt cttagcggaa ctgacaaggc cgattttttc cttgaacaca 2407081 gcgcaaatcg cgattgaaag cctgtttaag ttgattttgc tgctcggtta catctatttt 2407141 ttgtccatga caccgcttat taaaagagtg tttcaatatc atggagccga acataaagtc 2407201 ataaactgtt atgaacagaa tttgccaatt actgtggaga atgtccaaaa ccaatctcgg 2407261 cttcattacc gctgcggatc aagctttatt ttatttacga ttattgtcgg catgtttgtt 2407321 tatttactcg ttccgacaga tccgctttgg ctgcgtgtta tagatcgtgt cgcactgata 2407381 ccggtcgtgc ttggtatatc ctttgaagtt ctgcagctga caaacaaagt gcgtgacatt 2407441 cccggtctga aattacttgg gtacccggga ctttggcttc agctgttaac cacaaaggaa 2407501 cctaaggatg aacaggttga agttgccatc gaaagcttta acgaacttct cagactcgaa 2407561 gcattgtctg agcaaaatca gaagccttct cacaacgtca tctaaaatcc gttgccctgc 2407621 tattactttc ggaggtggac agttatgaat catcgtgtac aacctattat tgctgtatta 2407681 attgcgctgg gagcgttcgg tttcctctat gtgctggtaa ccaatcccgg agaaatggca 2407741 aaaatggcgg taaccgtcat cgtggcaggt atcattattt attttattgt gaaatatgta 2407801 atgaatcgaa atgcgggcag cgaaggagca gccttcaaaa aagcggcgaa acaatcacgg 2407861 cgccggatga aagaacaaaa agcaaaacac cgcgccggac ataagggacg tgtcagccac 2407921 ctgcgaagcg ttccgagcgc cagcaagcct aagccgatga ttctcaagaa aaaaagccag 2407981 actcagctga ctgttataga agggaaaaaa aataaaaaga aaaacagagc gcttttttaa 2408041 taggtccact gctttaaaaa cagctctgtc cgtcttttac ctagctcaat cagggctagt 2408101 tttttttgtt gtgttaaatg aaaatcagtg gccattacgt catcaacagg gagaaaaatg 2408161 atattttgtt catagcgtga cgcaatgtgc cttgcgtcat gagcatcctt catcgtttca 2408221 aacagggcgc cgaacagttc aaaagcgttg cggatatttt ttttcggacg ctctctttca 2408281 cgcggcgcaa gcgtgacacc gatcacaggg cgctttcttt cctttgaaaa cagccagatt 2408341 ggaaaattgc ttaacacgcc tccgtcgaca accgtggcgg tgcctgtgtc cgtttttaat 2408401 tttatcggtt caaagaaata cggaatgctg cagctcattc tgaccgctct ggcaaccggg 2408461 aacatatctg gatttaaccc gtaacgggcc aaatcgtccg gcaaaacaat catggtgccg 2408521 tttgtcagat cagaagcaat aaggcgcaga gaccctttct gcaaatcgcc gaaaaccctt 2408581 atgcctttcg ctcttaacag atcagcaatc catttttcta tcgtatcgcc tttgtataag 2408641 ccaagacgcc agtagatgga cacccactgg agcatcttta aggggagaaa tgagtacctc 2408701 tgatccagca atttctctcc gtccacttct tcaattaaag cgtggatttc cttactggtg 2408761 taacctgacg caatgaaagc ggcaataatg gcgccggcgc ttgtacccgc aactctttta 2408821 aagcggaagc ctttttcctc aagcacttca taagcgcctg cgagcgcaat gccttttact 2408881 cctccgccgg aaaacacacc gtcaatatac atctcattcc ctccccctcc atccgatcgt 2408941 ttattaccat tttaagaaaa cacgcgaaga aatagaccaa cgaatgacgg gtggcgtcag 2409001 cgtatcaaaa aagacggcct ccttcgagac cgccttttta ctgattatga tgttctgttt 2409061 tcttttggat tgatttcaga tcttttttac gggcatcatc ttcttcaaaa tattgaacaa 2409121 gatccccgat gcgatcaata ctgttccagc ttaaatgatg ttcgattcct tcgacatcgt 2409181 tatatatttt ctcttcatca acaccaatga ttcttaaaaa ctgctcaagc aattcatgtc 2409241 tgtataccag ccgtttgcct atttttttcc ctttagacgt taacacgaga ccgcgatatt 2409301 tttcataaat taaatattcg tctttatcta gtttttgaac catttttgtt acagaggagg 2409361 gatggactgc caatgcttcc gcgatatcgg aaactcgtgc atatcctttt tcttcaatca 2409421 gcatataaat ctgttcaata taatcttcca tacttggtgt tgtcatcgaa accctcccaa 2409481 aaagcacctt aactttataa accattacaa gtttacacta atgaacttga aaaaacaagg 2409541 atgctccgcg ggtcaaaagc cctgtttacc gcttataatt ccattcatct gaagcgtact 2409601 ttgtttcagc caagtgatga acaaaatcaa gctcttcctg agaaagttca tatggctcca 2409661 aatgaatgtt aagacctgtt tcaaatcctt ctttaaaggc tttacgagcc tcatccatcg 2409721 tcacccgctt ttcgatgagt tcattaatgg caaccgcttt atttttgaaa ttgcgctgca 2409781 tccgctctct tactctttca cttggatata agaacagatc gaacagcttg tcctcatcta 2409841 aatcaagaag aatggagcca tgctgaagaa tcacaccttt ttgtctcgtt tgcgcgcttc 2409901 ccgccacctt gcgcccctca accactagtt cataccacga aggcgcgtca aaacaaacag 2409961 atgaccgcgg attttttaag ctttcttttt ctttttcagt tctcgggatg gcaaagtaag 2410021 cgtccagacc gagatttcta aagccttgaa gtatgccttc tgaaataacc cggtaagcct 2410081 cagtaacagt cgccggcatc tcggggtgct cttccgaaac aattacgctg tatgtcagtt 2410141 cctgatcgtg cagcacacct ctcccgccgg tcgggcgtct gacgaatccg agattatatt 2410201 tatgtactgc ttcaaaattg atttcctttt taatattttg aaaataccct acagaaagtg 2410261 tcgccggatt ccagccgtaa aaacggataa ccggggggat tttcttttcg ctgtgccaat 2410321 ataaaagcgc ttcatcaagc gccatattga atgcaggact tgcattgcct gagtctataa 2410381 accgccaagt ttctttttgc attttaagac cttccttacc gttttaatag aatcagttta 2410441 tcaaactgtc gggaaaatga aaaatatttt agttccatta tagatgacaa tcacgctgtg 2410501 ctttactata atagtatttg tcgaaaacgg ctctatgacc ttgttttatg aagcagggtt 2410561 ttgattttat atgctaaagg agtagaatca cattgtctaa tatgatcgtt ttgattattt 2410621 ttgctgcatt tatcatctat atgattgctt catatgtcta tcagcagcga attatgaaaa 2410681 cacttaccga agaagaattc cgcgcgggtt accgcaaagc gcagcttatt gatgttcgtg 2410741 agccaaatga gtttgagggc ggacatattt taggcgcccg caacatcccg ctttcccagc 2410801 tgaaacagag aaaaaatgag atccgtacgg acaagcctgt ttacctgtac tgccaaaaca 2410861 gtgtccgcag cggacgcgcg gcacaaaccc tgcgcaaaaa cggctgcact gagatttaca 2410921 acctaaaagg cggctttaaa aaatggggcg gaaagattaa agcgaagaaa taaagcaaac 2410981 agctgtctgg tagacagctg tttttattta tctttcttcc gcctcgtatc tgagcactgg 2411041 gtgtctcgcc gcttttgttt catccattct ttttacaatc gttgtatgcg gggcctcctg 2411101 aacaagctcc ggattctcct ccgcttcttt tgcgatttga atcatagcat caataaacgc 2411161 gtccagtgtt tcctttgatt cggtctctgt cggctcgatc atgatgcatt cttcaacatt 2411221 aagcgggaaa taaatcgtcg gcggatgata gccgaaatca aggagccgtt ttgcaatatc 2411281 aagcgtacgc actcccagct ttttctgccg cttccctgat aatacaaatt catgcttgca 2411341 atggcggtca aacggaagat cgtaataagg cgcgagtttt ctcatcatat aattggcgtt 2411401 taacactgcg ttctcagtaa cagcctttaa tccgtcaggc cccatggagc gaatatacgt 2411461 atacgctctc acattaatgc caaagttgcc gtaatacggc ttcacacggc cgatcgcatg 2411521 agggcggtca taatcaaacg taaagcgccc ttcttttttg actaaaactg gctttggcaa 2411581 ataaggaatc agatcttgtt ttacgccgac agggcctgag ccggggcctc cgccgccatg 2411641 agggcctgtg aatgttttat gcaggttgag gtgcaccacg tcaaatccca tatcaccagg 2411701 tctcgccttg cttaaaacgg catttaaatt agcgccgtca taatacagtt tcccccccgc 2411761 ttggtgtaca atttccgcca tctctgtaat ctgctcctca aacaagccga gcgtgttcgg 2411821 attcgtcagc ataagagctg cagtttcttc attcactgct ctttttaaat cctctaaatc 2411881 aacaagccct ttttcattcg atttcaccgt aacggtttca aagcctgcta ctgttgctga 2411941 tgcaggattc gtcccatgcg cggaatcagg gacaatgacc ttcgtccgct tgaaatcccc 2412001 gcgagcttca tgataggcac ggatcatcat cagccccgtc cattcgccgt gcgctccggc 2412061 agcaggctga agcgtaacct catccattcc cgttatttct tcaaggtgtt tgcttaaatc 2412121 atataaaagc tctaatgcgc cttgcaccgt gtcttcatcc tgaagaggat gaatcgcagc 2412181 aaaaccagga atacgtgcga ttttttcatt gattttcgga ttatatttca tcgtgcaaga 2412241 accgagagga taaaaaccgg aatccacccc gtgattgcgt ttggacagcg ctgtataatg 2412301 gcgcatgatg tccagctctg aaacctccgg cagcgctgcg tcttcgtcac gaatataggt 2412361 gtctgacaag aggtccccca attcgatttc cggtacatcg agctccggca gactatagcc 2412421 gattcggcct tctcttgaaa gttcaaaaat aagtgcctgg tcctgattac tcatggcgat 2412481 cccccaattc ctgaatgagt gcgtcaattt cttcttttgt tctcagctct gttacagcaa 2412541 tcagcatatg gcagtccagc tctggatacg tcaacccaag atcatatccg ccaatcatgc 2412601 cttttgccag caaacgcttg ttcacagctc tcaccggctc atccagtttg atgacaaatt 2412661 cattaaacat cggcccgtca aacataacag taaggcctgc tttttttgct tcttgctttg 2412721 catagttggc ttttaagaga ttttggcggg ctatatcttt tacgccgttt tttccgagag 2412781 cagtcatggc cactgatgct gccagcgcat ttaaagcttg gttcgagcat atatttgatg 2412841 ttgctttatc ccggcggata tgctgctccc tggcttgcag ggtaagcaca aagcctcttt 2412901 ttccgttttc gtcttccgtt tgtccgacga gacggcccgg cacctttctc attaattttt 2412961 tagtaacggc aaaaaagccg caatgcgggc cgccgtatgc tgaaggaatg ccgaaaggct 2413021 gcgcatcacc gacgacgata tcagactgaa acttgcccgg cggagtgaga agacctagcg 2413081 ccagcgggtt ggctgaaaca ataaacatgg atttcccttg atgagcgata ggctcaatat 2413141 cctttagcgg ctcgatcctg ccgaaaaaat tcgggtactg aacgatcact gcggctgtgt 2413201 tctcgcaaac ggtttggcgc aatgcatcaa gatccgtaac gccatccgca gcgggtactt 2413261 caacaacatc aatatactga ccttttgcgt aagttttcag cacctctcgc gattcaggat 2413321 gcacggtttt tgacacaaca atttttttct ttttcgtgtg gcctgaagca agcattgctg 2413381 cttctgccaa ggctgttccg ccgtcataca tcgaggagtt ggcgatatcc atgcctgtca 2413441 gttcacagat catcgtttgg aattcaaaaa tagcctggag ctctccttgt gaaatctctg 2413501 gctgataagg cgtatatgcg gtataaaact cagagcgcga aatgacatga tccacaatga 2413561 caggctgata gtggtcatat acacccgctc ctaagaaaga agcgtattgt acggtatcac 2413621 gatttttaga ggccagcttt gtcagttctc ttgttaattc tgtctctgat ttcgcttttt 2413681 tgatttgatg ctctttttta tatttgacgt tttccggtat atcagcaaat aaatcatcga 2413741 tgctgcttac gccgatagta gcaagcatct cctgtttatc cttttctgtt gcgggcaaat 2413801 aacggtgctt catgtgttgt ctcctctctc caagaaaaaa tattagcgtt tataaaatgg 2413861 tgttttgaca acctttgctt tcactaattt tttgcgtatc tctacatcta caacagtccc 2413921 gatctcactc gtttccgaat caattaaggc aaggccgacg ttttttccta atgtcggtga 2413981 ctgcgtgccg gttgtcacct ttccgacaga cttgccattt tggaaaacct catatccgtg 2414041 ccgcggtatc cctttttcaa tcatttcgag accgacaagt ttgcgcttcg ctccgttttc 2414101 tttttgttca ctcaatactg acttaccgaa aaagtcagac tcctttttgt gctttacagc 2414161 aaagcctata cctgcttcaa tcggtgtaat atcccgggtc agctcctgac cgtagagcgg 2414221 gagcttcgct tcaaaccgga gtgtatcacg tgcaccgaga ccgcatggaa tcaatccgta 2414281 tgcatcccct gcatcgatga tttttttcca aatatgcata gcatcatcac tgcggcagta 2414341 aatttcatac ccgtcttctc ccgtatagcc agtgcgtgaa ataagtgctt tgcggccgct 2414401 gatatcggct tcatcaataa acgcaaacgg ctttaatgca gacacatccg catctgtcag 2414461 attttttaag atcgcttctg ctttcggtcc ctgtacagcc aagagcgcga tttgatctga 2414521 ctgattgtca atctgcacat cacctgctgc atgttctttc atccaagcca agtctttatc 2414581 tatattagaa gcattaatga caagcagata gcggttctct cctttttgat agataagcaa 2414641 atcatcgacg gttccgccat ccgggtaaca catcgctgta tattgagcac ggcctggcgt 2414701 taacgcggaa acatcatttg tcatcaatct ttgcaaaaaa gacagactgt cgttccctga 2414761 cacttcgact tctcccatat gagatacatc aaacaaaccg gctgcagttc ggacagcctc 2414821 gtgttctttt tttatagaag aaaattgaac aggaagctcc cagcctccga aatcaatcgt 2414881 ttttcctcca tattccttat acaggtcaaa taacggcgtt cttttcagca tctaattcct 2414941 cccctttatc aacggcgcag ctaaaaaaca tacaaaaaag gacagagaaa cacctcatgt 2415001 aaaatgaagg ttctctgtcc tggcacctga aagtttactt tgcatacgca aagacgtccc 2415061 ctttggtggt ttgcgcatcc gcacaaacac tctccagagt tgcgtcgagc aagagttctt 2415121 ttgcctgaga gattcactcc gcagtttgct ccttcggcgc ctgtatcccg aggttttcgg 2415181 tcaggtctct ccccttgctg tcattcgctc atattttcat gctgttatgg acatactata 2415241 gcaatatctt acatcaaata catactcata tcctaccatc atcactatat gctgggcaac 2415301 agcaatttgg gcagattttt cttatattat tcatcttaag aatcgaagaa taagaaaggc 2415361 ggtttcaaag caatgaatac agaaatgatc tacgatgcaa aatggcctga agaatttgct 2415421 gaaagactga aaaacgatgg cccttgggca aactgggaac tgtacaagct ctctgcagaa 2415481 atccagaaaa cattagcaat tccagagttt gaaggcttac gggctccttt atatctgcct 2415541 tcctttacgc cgctccccca ccagcttgaa gtggcgcaaa aagtggttga aaaaatgaac 2415601 gggaaagcga ttttagcaga tgaggttggt ctcggaaaaa cggttgaagc tggactgatt 2415661 ctaaaagaat atatgattcg cgggttagca aaaaaaattt tgatccttgt gcccgcttcc 2415721 cttgtgtcac agtgggtcaa agagcttcag gaaaaatttt tgattccggc tgttgaacaa 2415781 aagaaaagct atgtgtggga gcaatgcgat attgtcgtct catcaataga caccgcgaag 2415841 cgctcgcccc atcgagaaat cgttctgtct atcccatatg atcttgtcat tattgatgag 2415901 gcacacaaac tgaaaaatag caaaacgaag aactatgaat ttgtccggaa tctcgtaaaa 2415961 aaatattgcc tgcttcttac cgcgacgcca atccagaacc gtatcgaaga gattttcaat 2416021 ttggtgtcct tattaaaacc cggccattta ggcagtcaga atcactttca ggaggagttc 2416081 gccaagaaga aatccagttt agaagcgcat gaacatttaa aagatcttgt gaataaagtc 2416141 atgatccgta acaggcggca tgatacaggg ctgaattgga aacagcgcca tgttgaaaca 2416201 gtgccgattc aattttctcc atcagagcag gcgctttatg atgaaatttc tcgtttgaag 2416261 gacagtatca ataaaccagc cagcatgttc tcgattatga ccttgcaaag agaatgctgt 2416321 tcgagcagag aagcggtata tatgacgctg aaaaagatgc ttgatcaaaa agagaaacaa 2416381 gcacctgcca ttgatgagga tacgatttca gttttgatag atcgcatcaa tcaagtgaca 2416441 caaaactcta aagcgcttca agttgttgac ttgatcaaaa agatcgacga taaggtcatc 2416501 atttttacag aataccgcgc aacccagatt tatctgcagt ggtttcttca gcaaaacggc 2416561 atcagttctg tgccgtttag aggcggattt aaacgtggaa aaaaagactg gatgaaggat 2416621 cttttccgcg gaaaaatcca agtccttatt gcaactgaag caggcggtga gggaattaac 2416681 ctgcaatttt gcaatcacat gatcaactat gacctgccat ggaacccgat gcggcttgag 2416741 caaagaatcg gaagaattca cagactcggg caggagcgtg acgtgcatat ttataacatg 2416801 gcgacaaaac atacggtgga agagcatatt ctaaagcttt tatatgaaaa aattcatttg 2416861 tttgaaaaag tggtcggtga acttgatgat attttaacga aaattcaagt gaacaatttt 2416921 gaagagcacc ttcatgacat tttgtatcac tcagcaacag aagaagaaat gaaaataaaa 2416981 atggataact taacctcatt tttgtcttat aaaaaacagc tgcctgctga aaaaagagga 2417041 tcttagcctg taaggaggtt ttattagtga gacagcaaga ggttcacgat tttctgctgc 2417101 gtttttttca agcaaacagc tgccaaatcg tcgatcaagg cttaggctat atgacagtgc 2417161 agcttacagt tgaaatggac aaacaaatca tgaaccgccc tttctactgg cattggcgcg 2417221 agaagacagg cggtgatccg aatccaatga aaatcacttt tattacagat aaagaaaatg 2417281 cgccaaaaga cctagatggt gaatttatat attttggggc cccgcgtctt tttcaaatat 2417341 tcaaagctgt taaacaaaat gggagattta ccagaatgta tgagaaaatt gaatcagccg 2417401 gagctaaagt cccacttcag ccttggcttg gtataaatgt cacgatttca taccagtccg 2417461 acatgaaaaa ggataagtta ttgtcactag gtcttcacct agtctctgga acgataattg 2417521 aagattttca aagcaagctg acccagtttt cactgacgtc tcaaatatgt gactattgct 2417581 tcaccatttc acctatgatc aaaccagaaa gcggacttaa gcgtatggaa aactatattt 2417641 ccaaatccgc tatgcaggag ccgtccgact gggcggaaca ggcggttaac aggtggaaga 2417701 atgatatgac attgcttgat aagttttacg agcatataga agaaaaacca gaagaatacc 2417761 atctagaaaa acaggcgctg aaaaccttgt atcaaccaaa gatatcagtt gaaattgaaa 2417821 atggcggatt gttttatctg caaaataata tttcaagcta acttttttac cattcgacat 2417881 cattctcgtt ttttttgaga aaatacgatt ataataaagg tatattggaa aaaaattctg 2417941 gtgatttaat ggcaaatgac ttccagagac taatgaagca tacaataagt catggccgga 2418001 ctggctgaaa tacataaaca agtattttag gaggagaaac tgcatgaaga atgcaaaaca 2418061 agagcacttt gaattggatc aagaatgggt tgaattaatg gtggaagcca aagaggcaaa 2418121 tatcagcccg gaagaaatac gaaaatattt acttttaaac aaaaagtctg ctcatcctgg 2418181 tccggcagcc agaagtcata ccgtaaatcc tttctgaatg tgctataata tcacaaggaa 2418241 ggtgatgaca ttgattggcc agcgtattaa acaataccgt aaagaaaaag gctactcact 2418301 atcagaacta gctgaaaaag ctggggtagc gaagtcttat ttaagctcaa tagaacgaaa 2418361 tctacaaacg aacccctcca ttcaatttct cgaaaaagtc tccgctgttc tggacgtctc 2418421 ggttcatact ttgctcgatg agaaacatga aaccgaatac gatggtcaat tagatagtga 2418481 atgggagaaa ttggttcgcg atgcgatgac atccggggta tcgaaaaaac aatttcgtga 2418541 atttttagat tatcaaaaat ggagaaaatc ccaaaaagag gagtagtgcc tgagcagagg 2418601 cactaactcc tcttttgtca ataaccatcg agacggccca gtatatgaat actgggccgt 2418661 ctcttttttt tgctgttatt aatttttatc ctcgctatgc gctttttcat tttctttcac 2418721 gtaaccatct ttatcagtat ggtccttttt gattgtcaag ccgttccact gtgtagcttc 2418781 gaatgagaat tgaagcttaa tggagttgcc ttgatattta ttttgaacca taagcccttt 2418841 ttcatctttt gttttatcat ccttgaattg gatttccatt tgaacctgat cgaagtcagt 2418901 tggtgttttt ggaacaccat catattcagg agcggtttta ccatcaattg ttgctacatt 2418961 gactttaccg cttgcattta agaatttagg gtcaatttgt tttttgattt tttcagcagc 2419021 cgctgcatca tttttagcag acatcaaata caagtcttta aggttcgcat catctaaaat 2419081 aatgtttttc gggtagccat tgccgccctc ttttccaact gtcaacaatg tcacttcaaa 2419141 ctggctgagg aaatcttctg gagatgtatt gctgccgccg tttgctttaa aatctccata 2419201 attaagcgcc attagaactt ctttgatcgc aagtgatccg ttattttcaa attggaaatc 2419261 ctttgtcaac ttatctcccg gctttagatt tgataagttc acactcgctg aattctcttt 2419321 agcagataaa tcaagcgtac ctgatgcaaa agtagcatcc tttgatttaa tgtcgttaaa 2419381 tgctgcccat gttcctcctc caactaaagc taatcctagt gctgcagaag caactcctaa 2419441 actcaatttc tttttcatac ccatggtaag ctcccctttt attgaatgat tttatatcga 2419501 aacctgttgc caggtttaca actgaagtta agtagacatg gtgctgtcct ttgtatctgt 2419561 ttccaaggct tttgtctttc tttcaatttc tctaatggcg ctgctgatcg tcacaaaagc 2419621 gtaaactaac agcatcacgc cgggaacaat caataataca gccgttccaa tcggctggct 2419681 ggcaaaatga agcatatagc cggcatatgg aagctgaaaa cctgtgtatt gcgcgcgaac 2419741 attttcgtcc gatacaggcg ctgaatcagc tgctgcatta ttatcacctt ttgttttaaa 2419801 taacaaatgg tctccttgct ttgttatgtc aacaattctg tgggtgaccg ccgtatttgc 2419861 atcctgcata aatgtaataa cgtcaccttt ttggagctct ttcacatcag tgatttcttt 2419921 gaccaatatt aaggaacctg tattgaactc cggctccatc gaacctgaca gaactgattt 2419981 cagcgtatac ccaaacactg ccggctctcc cccggatgaa cgtgttgaaa tcacgacaag 2420041 tgtcagcaca ataataagag taaagatgat cacgtataaa atattactga tcagcttcat 2420101 tgcttttttc atcctcttcc ccgctttcct tctggtctga ttgagtttct ttttctttgg 2420161 ttacagcttc ttgagatgtt tcttctttca ttgttttttc cggtatatct ttttgtgttg 2420221 tttcattctc ctttttgacg tccgactttg tttctttttt agggactgtc ggtttttcat 2420281 cgcattttgc aagcctcata ggctccgacc actcaaatgt actgccgttt gccgggtagc 2420341 ctgccggttt atatacttta aatgcataaa tgccgggttt catttttttc ttggtctcaa 2420401 ttttataaag tgaatcgccg atttgattgg agacaaatcc tttttcgatc acgttcccat 2420461 cctttaacgg tttgcgggca ttttcaagct tatgaagctc ccacttccac tttgatttct 2420521 taagtttctc acctgtattt tcgagcacag caaataaggc gaaaggtgag catacagtgc 2420581 ctttcgtatc cgtttgatct gatatgtgca aatcactttg atcccagcgt ttatcataat 2420641 ggcagttttt atctgtatgc tgaaagtctt tacacgtttg aagtgagaca tcaaatgttt 2420701 caatatcatg aaaagcagcg cttgtatcat cggaaaattg taagcatatt gcggcagtca 2420761 gactgaaaat gactgaaagc tgaaagataa gcagaacttt cagtttcgtc ttcgcctttt 2420821 gctgattgtg aaacaatcga aacatatctt acctcctgta aaacactgta acttgatatg 2420881 acaatcgttc tctttaaaga acttcacaaa tagagtataa tcaacgattt atagatttaa 2420941 aaacaccgaa atcgctcatt ttgttcgttt aaaagaatgt tttcatcata ttacaaagtc 2421001 ttgctcagta ttgctcattt tttcaatttt ttagaaattt ttgggattgt tatgtgagaa 2421061 tttaaatgca tatcccatta ttatttggta ataataaaca aagaaagggt gacagcatga 2421121 tgatcaaaca atgtgtgatt tgtctatctc ttctcgtctt tggcaccaca gccgctcacg 2421181 cagaagaaac accgcttgta accgcccgcc acatgtccaa atgggaagag attgctgtaa 2421241 aagaagcaaa aaaaaggtac ccgctcgcac aggtactgtt caaacaaaaa gtatgggacc 2421301 gtaaaagaaa agatgaagca gtgaagcaat accatttaac tctgagggaa gggtcaaaag 2421361 aattcggcgt ttttgtgacg atttcatttg atccttatag ccaaaaggtc aataaaattg 2421421 ccatattaga agaatatcaa taaggtcctc cattttttga aggaccttat tcgtttattt 2421481 gcggttattt tttccgtttc agccaaagtc ggaagccata gggtaaaata ccgaaccact 2421541 gctgggaaac aggcgttttt gtttctttcc gcacctcttt tcgttctttt cgctcatctc 2421601 tcggagtatc tatatatttg acaaattgct gcgtcatata tttaacataa tcattcgttt 2421661 tcacgtgatc acctcatcat tcaattatta tgagtgttgt ctcacatgac tttttttata 2421721 ccctttacac tgttttattc tgtccatctc agcagttttt tctgtttttg gtcaaacacg 2421781 atctgtgcag ttctttctgt tcccgaatcc gttgacactc ttaagttgat ttctttttgt 2421841 tcttttatcg atgtatcatg aatgtaataa gaaacccgtc catatagaaa ttgctgcgta 2421901 ccctcctggc ctttccgttc ctctagaaca tgccgaatcg aaagaagcac cccattttga 2421961 agcaaattct ctcctatgta taactctttt gtttccttct caaacatgca gcgtgaaata 2422021 tattgagcag caacaaagtt cacgattaac agcacaagcg ctgacacaaa aagaacagct 2422081 ggataaataa accctcttgt acgatacatt cacccccctc ctaaatacga atagactgga 2422141 aaagcagttt gatacacttt ttggtcttca ctctcaattt tcagcaaaac aacaccattt 2422201 tcaatatcag ctttcatggc agtaatatga tctaaaatcg gaacatgccc tttgccatcc 2422261 actctttttc ttatcattga atgataaatg tcaaaacgga tgtcttgtcc ggaaagattg 2422321 gtgcagatta acacgctccc atgctcggct gtcttaactg cctgtgattc cttgcattca 2422381 ttcatcatct gttctatcga aatcatccat tcctgctgtg tgaaaccgtc atgttcctgc 2422441 tgtcgagaca aaaacagatg gataatcgca gctaacgatc ctgatatgag caaaaagact 2422501 gagagcgaaa ataatacgtt aagaagcgtg tagccattct gtctgcaaaa tgctgaggca 2422561 aaatgatttt tctttataag ctgcggcttt gatacatacg ttttgatatt cgccctcctc 2422621 ctcccacttc attgcataga tatgattgtt ctttgtaatc gtttttgacg cggctccttc 2422681 accactcatg acatatttgc taatgctctc attcatcatc tgatagccaa tttctcgtga 2422741 ttccgccatt ttttcatcag ccatcagctt gtcccacaag gggacgactg tcagcagcac 2422801 aaacagccac aggcttagcg cagacattgt ttctattgta gaaaaacctt tattttctct 2422861 ccacattgac tctcccgctc cctagataaa ctgttatgtc ataaacggca tggcctttta 2422921 ctcgtatttt tccgcctgca ttcgggtgcc ctttctcatt aaattccaaa cggtctttta 2422981 atgtcagcag ttctatagaa agtcccgttg catacggacg ttcaataacc gtatcaccaa 2423041 tgactaattg atattctttt ttatgaaaga gaatttttgt tctttgttga cgggaaatag 2423101 cagtctgctg tgtgagcata atatcatttt tcagctgact tgctgcctgt cggacagctg 2423161 tattgtcata agcaggagga agtgtagtga agacggccac caggaggata gaggcaaggc 2423221 ttaacacaag caaactttct aaaagggtaa accccttctc ctcgtttaat ttaatgttca 2423281 accttaactt ctccgccggt gatgataatg cgcttaccat ttggacagac agcatccttt 2423341 ttcacatagc cctctgactg taaatcggca aggctcggag tttgtccttc atgatcaagc 2423401 tcaaatgcag tcatttgtgc cttaaccatg ttttgtaagc cttcacagcc ctttttttga 2423461 atggtttgat tatgtttcgt gacgttcggt atcgtaatta aaagcaaaat cgaaataata 2423521 aagagcacga ttaacatttc aacaagtgta aatcctttct cattcatcag cctcttcctt 2423581 tcacatttga ttcatcatct gatacatagg cacaagcata gataaataca caagtaagat 2423641 catcgctgca acaaatccat aaatcattgg ctgaaggatg cctgtccatt tttgcgcttt 2423701 gtgttccagc cgctgtaata tgaattggct gtatgtgaaa agctcccgat ccaatcggcc 2423761 gctcagctgg ccgtgagata tgacttttga taaatcagtt tcataaaaaa ggcttccaca 2423821 aatagcggat tcaattgact caccggcttt tagccgttca atcaattgtt cagcctcgca 2423881 gcggtagaaa gggagaaacg tttgatgttt aaatgcatta aggctgtcat aaattgagag 2423941 gcctgatttt aaaaggctgc ttagctgcaa agaaaaaaag tagctgttaa acagctttac 2424001 aagctttcca accaaaggaa tcctgataca aatcagcatt tgccgggcag gtgatttttt 2424061 cttaaacaca agccaataat aaatcccgat acctgctgta aaaagaacaa gcaaaatgat 2424121 cacaagatca atatgctgaa aaaaagcaaa aagcatatcg gttgaacgtg aggtttccat 2424181 attcatcgat tgatagatac cggaaaactg aggaatgatg atggactgta acatataaaa 2424241 catgacagcg accgtaaaga tgaggaaaag cggatagcgc agcactcttt tcagctggtc 2424301 tgcctgtgca atttttcgtt ccagcagctc tccgctctgg atcattgaag caggcagttc 2424361 accatgtgtt tcagcaaaat aacaaatacc tacggcttcc ttatgaaatg acaaactctt 2424421 tagtacttga taaaacggag ccccttccct caaacaagtg accgaatcag tcaagtcagc 2424481 cgcctgcctc ttattcatct gaagttccat caggcgtaat ccatccagaa gtgtatatcc 2424541 gcccgcagtc atttcaccga gcctctttaa taacctggct tgatccttta acaaccagac 2424601 ttttctaatc tttttcatga taaacccacc ggtcatagtt gtttgtcgtt aaatagccga 2424661 gcgcaattcc ttttctgata atttgacgaa gcgtttgata ttggtaattt gcatgatttc 2424721 cttttgcctc ctggatacat tgctgaagat ttttcccgta tagaagctca taaacgctag 2424781 ctctcctagt atttcgtgac tgtcggcaat acactgatga acatccgttt tcacaaaacg 2424841 ggcaagccaa atcaaccaag cgctgagccg ctattgcaat gacagtctgt tcgatttcat 2424901 tcatattgat accgaattca agcagtctgt aaattgcgcc ctttgcgtct ctcgtatgaa 2424961 ggctcgttag taccagatgt cccgtcatcg ctgcccgcac cgcaatttca gctgtttccg 2425021 cgtctctgat ctcacctaaa ataatcatat cggggtcatg gcgcaaaatt gctttcagac 2425081 ctgcggaata agttacaccg gctttttcat tcacctgaac ctgaagaaca tcttcgtccc 2425141 ttgtttcaac agggtcctct aatgtgacaa tatttcgatt aaagtgtttt tttgcatatt 2425201 gaacgagaga gtataatgtg gtagtcttcc ctgaaccagt cggcccggta aaaatgagca 2425261 tgccatggga atgttttaaa aacgagagta atgtggctcc tgtcttcgga aatagcgaca 2425321 atttatcaat cgaagggata ttgtattggg gcatcactct gatcacgagg ctttcttcat 2425381 taattgtggg cagcgttgac attcttaaat gaacatttcc ctctttcaac tttaacgtaa 2425441 gcgaaccgtt ttgcggcttt cgcctttcac ctatatccat tgctgaaaga aatttaaaat 2425501 gtgaaatcag tcttacgcac tcttcttttt tcatgtccct ttttttcagc aaggcatgat 2425561 cgacccgaaa atgaatgata gcgtcccgct ccctcggcac aatgtgaata tcagaagcct 2425621 ttgttagata tgcctcttca atcaagtttt tgcttacctt ttctattgaa tccaatttga 2425681 ttccctctcc tttcaacgca tattgtagaa aaagaagaaa aggtaatcaa acagggaaaa 2425741 cgtgattttg tgagatgtta tatgctgaaa aaccaattct ttctggcaag aaaaaagact 2425801 ttcaactgaa tgtacccctg tcattataat tttccctata aataaaaaag cagacatggt 2425861 caccatgcct gctagattcc attttcatta tgctgttttc gcttattgac cagtatcttt 2425921 ctcaacggaa agatcgccta atgcaacaat accggtcatt tggtcatttt caagaatcga 2425981 taaactgcgg atttaatgct ctgtcataag ccccttgaca tcgtatccgg tcaccctgat 2426041 atgtctggtg aaaaagcggg gcacgctgca caaaatatga aacatcctat agagtccgcc 2426101 tttttcgagg tttctttttc ttcttccgct cctgcagcat atctcccgtc cagccttttt 2426161 ttctcaaata gagatagatc agaactgtag atgtgacaat caataagagg gaaaagagat 2426221 atccgtattt ccaattcagt tccggcatca ctgaaaagtt catcccccat aaggcaccca 2426281 gagctgtaat cggagtaaaa agcgtcgtga aaatggtcag cgcttttaca atttcattcc 2426341 ccctatgtga ggtaatgact tcctctgaat gcagcagatt gttaagctcc ccttcaaatt 2426401 cgctgatgta tgtaaatccc ctgtcaatct tcagttgtgt ccgctgataa tcctttttcc 2426461 cttcattttg aggtaaaaag gtttctttca acgccatttc aattttttta gcgcttaata 2426521 tcaaattttt ccaaatcatc agttcatggc gcaggagatg gacgcggttt aaaatgcttt 2426581 tgctattgtc gtctttaatt tgccatctga gctttctcag cttgacttca aattcatcaa 2426641 caccgattaa atacgcattc attagttcgc cgagaagaat taaaaacccc tctatcgcat 2426701 tgtccgctct ttccatttgc cgaacaactt ctttgccttt aatctctctc aaaattgaaa 2426761 agtcaaagtt gattgtaaaa aaatattgtc tggtgatata aaagtgaaaa acagtatggt 2426821 ctttttcttc accaagcccc tgatcataaa caatcgaccc aaatactgct tcattttccg 2426881 tttcagttgt atctactcgc aaaaaattaa cgtgatggtt attttcaaac cacttttcac 2426941 actgaggcca gtgagaaaaa tggattagat ctcttgcctt acttctttct tgaggcccca 2427001 tttggtacca aaaccaatcc tttcccgtat gtgccttcat gtcaagctcc tccaaacttt 2427061 tgttctttat tctttaattg cccaataacc gcgtcactaa accagtctgc cgcttcaaca 2427121 catgttttat gagcattttc aggtggtatg gaatgtagaa agacatcgga aaagggaggt 2427181 gcatgccttc cttggagaag gcagttgttt tggaatttat caatttacta gcagtcgcta 2427241 ttctcatttt gttaacagga tttttcgttg ccgtagaatt ttcaatcgta aaagtgcggc 2427301 gatccaaaat tgatcagctt gtcgcaaaag gaaagaaagg tgctaaagcg gcaaagcatg 2427361 tcatcactca ccttgatgaa tatttatcag cctgtcagct gggcatcaca gtcgcagctt 2427421 taggactggg atggcttggg gaaccgactg tgcaaactct gcttcgaccg ctttttcata 2427481 aagcaggctt aaatgaatcg cttacccacc tgctttcact cgtcatcgca tttttagtgg 2427541 ttacgtattt aaatgtcgtt attggggagc tggcgccaaa gagtttcgcc attcaaaaag 2427601 cagaaagcat taccttgttg ttcgctaaac cgcttatttg gttttataag atcatgtttc 2427661 cattcatttg gctgttgaac cactctgccc gattgattac aggagtgttt gggctgaagc 2427721 cggcatcaga gcatgagctg gcttatacag aggaagaact tcgggtccta ttggctgaaa 2427781 gctataaaag cggcgagatc agaaaaagtg aattaaagta catgaataat atcttcacct 2427841 ttgataaacg aatggcaaag gaaattatgg tgccgcgaaa tgaaatggtt agtttgtcac 2427901 tagatgaaga ctccatttca aatcttcagg aaacagtcaa gcaaacaaaa tatacacggt 2427961 acccggttgt aagagaggat aaagataacg tcattggcgt gattaatatg aaagaagtgc 2428021 tgttttccat gctgacgaaa gatttttcaa tcaagaagca tcaaattgaa cctttcgtac 2428081 agcccgttat ccatgtaatt gagacgattc ctatttataa actattgctg aaaatgcaaa 2428141 aggaacgcac tcatatggcg atcctcatag atgaatatgg cgggacgtcc ggtttggtca 2428201 ctgtcgagga tattatcgaa gaaattgtag gagaaatccg tgatgaattt gatgcggatg 2428261 aagtgcctca tatccgcgaa cttggaaagg atcattactt gttaaatgca aaattattaa 2428321 tcagcgatgt taacagcctg cttggaaccg atttatcaga ggctgaagta gacaccttgg 2428381 gcggctggtt tttgacacaa aacatagacg ctgagcctga aagtgccata gaatatgatg 2428441 gctactcttt taaggtaaaa gacatcaaca gccatcacat tttatttata gaagttaaaa 2428501 aagctgaata gcccgtgaaa ggctgttcag ctgctatctt tcaagataaa catggcaaag 2428561 gcatcaacac tcttttattt taaacccttt attggccagg gctttagcaa gactttgctc 2428621 tgttttcaca ttcgaaaaat ccagacccag cttcacgaca gtttgggcaa tttccggcct 2428681 gattcctgaa ataatagtct caatgccgag caatttggtg ctgtcaatca ctttaaaaat 2428741 ttgataggct accatggtat caacgatagg aacgcccgaa atatctaaaa ataaatacga 2428801 gagctttaac gctgagcact gctccagcac agactccaaa atcgtcctcg ctctgtgcgt 2428861 atcaatttca ccgacaagcg gaagaatccc aattccatca gtaatcggca taatcggcgc 2428921 actcaattca ttaatcattt ctttttgcgc gtttaattgt atcatggtca cctggtgata 2428981 ttcttccgta aacacttcga tgatctcatc aatgttttga ttcaagatcc ggctccactc 2429041 ataaaattcc tgaatgctga tgtcttgaga agaagcttcg ctgaatttat gaatccattc 2429101 aaacatgatg tgcctgaaag tgttaaactg gccgacactt tgtgtaaccg tcacttcatg 2429161 aacggcacgg tctctggcgc attgaagaga ccaccggttg agctcatcct ctacgtcttc 2429221 ttttctaagg gattttgcta cgatggtcac caataattca tgctggtctt ttaacttttg 2429281 ttctagtttt tgctgatctt tcgctgaata cagccagctg ccgtttgacg tacaaacttc 2429341 cagccattgt tgcgtaatat cttttttgtg ctctgttaag tgctgatcaa gagctatcat 2429401 cttaatgagt tacctcctgt ttttgaaaaa tgtacgctat atatgtataa cgcgtctgcc 2429461 tttacacata ctatgtttag attcaatggg ctatagccaa gcggtaaggc aatggacttt 2429521 gactccgtga tcgttggttc gaatccagct agcccagttt ctgaacaggt gaaaaaccga 2429581 agataagctg attcgtataa atcagcggat cttcggtttt tcatcatgca gattgatgaa 2429641 ccgttttctt cttcgataac ttcaacagtt ctcccgggtt ataaccaatc accagctttt 2429701 tgttgtctac tagaatcggg cgtcgcaaaa gcttcggctt ctcgattaaa agttccagca 2429761 cctcatttac cgtcatttct tcaatgttta aatttaaatt tttgaaagtc tggcttcttg 2429821 tcgccaaaat ttcatcaatt ccttctgtcg ttaacgataa aatgtacttt aattcttctc 2429881 ttgtcggggt ttctctgaat aagtgccgtt cgttaaattc aatttgatgt gctttaagcc 2429941 aatgttttgt ttttcggcat gacgtgcagc ttggatatga gtaaaaagtt aattgttgtt 2430001 ccattcgttt tttcctcctc agttaaccat ctctttgtag aataactacc cggatcattt 2430061 ttcatttaaa ccatttacag aacttttttc ggattatttt ttaaaaaaca ttcatacaat 2430121 agaaaacaca atcaaaggga caaattccat ttgtatatta ataatgaaaa tgtttacatt 2430181 tctaggtgtg atctattata ataacagtca gagggactct cgggagggga taaaaatgaa 2430241 tcgcatgttc cgggtgttag gattttggac gggaattttt gcagtcatgt tttatttagg 2430301 tgatatgaaa gatgcttccc ttttattttt tggacagacg atcttatttg tgtttctatc 2430361 gtatttgaac ttaaccgaac gcatgtatat ttatattttt ggcgcttatt taacaatttt 2430421 cttcgccggc tttacatatt actcaatttt tattatggtg cccggcggcg gaggccatta 2430481 aatgcagaaa gagacaaacc ttatcggttt gtctcttttt ttacaatgaa aacccattta 2430541 aaaacggatt ttgatcctgc tcagtcagta cgtctgtttc aggtccatgg ccgcttaaca 2430601 ccagcgtgtg ttccggaagc gtaagcagtt tttcatgaat ggacgtcagc agcgtctctt 2430661 gattgccgcc tattaaatcc gtacgtccta taccgccttg gaacaagaca tctccggaaa 2430721 tgaccaagtc tgcatctttc acgtagtaag acacactgcc tggtgaatgt cccggcgtaa 2430781 ataatgtttc caaatgaaac ggcccgatat tcaactcacc gtcgccttca attagatgat 2430841 ctgcaggctt agctgtgact tctatccctc gcagcatgcc ggagccgttt aaagaagcgt 2430901 ccgcaagcca atttttttca ttttgatgca ggtaaacagg gatatcccat ttttctctca 2430961 cttcatcaag cgccccaata tggtcaaaat gggcatgtgt aagcaaaatg gctaaaggcg 2431021 tcagcccttt ttcttttatg tattgattga ttttatgtcc ctcgccgccc ggatcaaaaa 2431081 tcagacattg atcatcactg atgagaaaat atgcgttcgc ttgaatcggc cctactggca 2431141 ttcgtctcca tttcactatt atcacctctt tcttttttat gctcttatta tgagggtttt 2431201 tgaaaaaaga ttcaaacaat cgcaatgaaa acgctatcga caaacctata aaaaacaggt 2431261 agaataaaac tggaaagaat tgcaggtttt tcaatgtaaa gggggctgtg ttatgttact 2431321 tgtcgtgatt ttcggccttg tcgctctttt cgctttatgg ggagtcttgc gttctgttag 2431381 aaataaaaat atactcgggt ttttattagc cggtgccacc ttatttgtct ttggatggtt 2431441 taccgtgatg accgtaataa acagcgggta tccaaccgca cattaaaacc tgtatccgat 2431501 cggatacagg tttattttta tggctgtaaa tgtttattga cactttctat tttgctctca 2431561 agcgtcgttt ttttgtcacg cctgtcatcg atacggatat tcgttgccac tctgtgcaat 2431621 cctttttgaa atggcgcttc gtgaattgcc tgaataactg caaaaaggtc actgagttct 2431681 ccctcgatca gcgtattcat cggtgtcagc tgatatttga ttttcccttc tgcttgatat 2431741 ccttctaata tcttttgcac atcggctacg taagcactga cactgggtgt ttccgtaccg 2431801 attgggataa tggttacatc tgcgatagcc atcgttattc catctccttt tgatcaatga 2431861 tgagttgctt cgtttcatgt gatttcaata aaataatttg ctcaaaatga aagccgtata 2431921 acgcatattt cccgttcgga gatatttgaa tcggctccat ttcccgcaga gacacaagat 2431981 cttttgtctc tcccgatgct acattgattg ctgcgagctt atatgcatcg ccgctttgtt 2432041 tgaatgtata aaacaggcct cctgcttcat catagtcata ctccattgga gccaaacttg 2432101 tatatttcgc ttggagcggc catttcgctg taacaggtga tgttgattgc ggcgttttaa 2432161 actgatacgt cccttttcct ccggaagctg atttgacagt aaaactcatt tgatggaaag 2432221 aatcgaagaa tagaacgtta tcctcaagct tctgttccgt cttagaagct gtatcgaacg 2432281 tatataaagg ccctgtttta tcgtctctac cctcttttac ataatcaaat gtatttttgg 2432341 atgtccaatg aatgaacgga acctgtactg ggcttaagaa agattcgtct tttttagcat 2432401 tcacctgata tgtatggaaa tcccagtttt cattgaattc cgtcaccatc atttgataag 2432461 gatcatactg attccaagca gcttcaagct catacgtttc gtaatctttt tcgtaaagcg 2432521 tctctccttc tgcattaagc aaaaccactg ccgtcttttg gctatgtgtg atttgcagca 2432581 gaatcatctg ctccctcgca ttgatttgaa catcaacgat ttgaccatcc gtttgataga 2432641 gctttttcgc tttgcctgta aagatgcggt acgcaaaaag ctctgttttc gtcggattag 2432701 acgcagtata taatattgtg ctgttattca gccagccttc cgccccatcc gctttttccg 2432761 cggaaagcgg tatgatgtct tttttctcat cttttgccgc cgatgcctgt ttttgctgct 2432821 gatgagatgg ttcgcatgcc gataaactaa acagcaatac cgccagcaga ataaaacaaa 2432881 ctgatctcat cagcattccc ctccgatcat ctttattctc tcatatttgc ttcggcagaa 2432941 aaaagaaaaa gtttcagtta ctcatgaaaa aataacgccc tccacaagat accgcttgtg 2433001 gcgttatata tgtgtgaaaa ctgctgaaac ggcaaaggat tttggccttt tccaagttcc 2433061 accgtatacc cttccttaaa ataatggtga ataaaccaat cacgaaatcc agcatagctg 2433121 tctatatccc ttactccctt ataaatgttc ccgcttaact cctcaaactc ctttatgacg 2433181 gcagcagatt cctcaggctc aaggccttta tagccccaat aaatttcttc tccttgagta 2433241 tgaagagcca gcagtctgtc aggcggattc tccgtgatca gccggtacat cgcaatagat 2433301 tccggctccg taagcggaga gattcccgga aaatcgcggt agctgggtgc tgtcggtttt 2433361 cggtattttt caatttccca taatgatgga aattgtttat ttaaatcaac cccgtttata 2433421 ttcgccttcc attcattaaa atttggacga tgttcattta gcctttcgag ttcatctctt 2433481 ctggctccca tgacttctga tccgtttaaa acaagatcaa cgccatccgg attgacaaga 2433541 ggaacgaggg ataaggatgt gctgttaaac agctttatgg gagaaaagcc aaagaaaggc 2433601 gaattgcagc ataatgacat acagtattcc ttaaaccatt ttagcaggac agacgttgta 2433661 atccactcat tcgcatgaaa tgacgcgttc atatggacct tttttacggc atgctcccca 2433721 ccagccttca gctcccagat aggcctgccg agtacagaac ggccaatttc ccggcatgag 2433781 acaaacggaa aaacatcaat aatcttcttt atttcctttt caacagctga atcatcatag 2433841 attttctctt gctcaatcca gctatctgaa agtttcagct gccgaggctg taaaaagcgc 2433901 tttatgtcct gaatggtttg aagctctttg ccgctatgct cctctatcac ataaccaggg 2433961 caatacaatt gatgtttttg tgcggagcga tttgcacttt taagcaattc ctcgtctatc 2434021 ttcagttctt tcgccacatt ggccaaattg ttcttgatct caggtttcac cgtaataaac 2434081 gccatcatca tccccctttt ttgttactat atgacagcgt atttaaaaaa agaaagcctc 2434141 ccgctcactt cgatgcggga gacattgtga ttatgatgcc tgatcaagca tttgtttttc 2434201 tttccgcttt gacgaattgt ccagcctttt ctggtcataa aatcgcaaca aatccccata 2434261 aatgatttca tcagaaagtg atagctcctg ttttgcttta tcagcaaatg cttcacattg 2434321 ttttgtctct tctaacggtt ttcccgtctc tttgtcataa cacgcaccgt ctgtataaac 2434381 aacctgatct gtgataaagc tcccgtcccg gagcaccgtg aagtccagtt tttcgtctga 2434441 aagcagatcg ttgccgaatt gaatttgatc tttcgtatca atccctaaaa gattcatcag 2434501 cgtcggcctg atatcaatct gcccgcctac tgtttcaatg gtttgcggct ttttatcagt 2434561 aatacccgga atatgaatga ccagcggcac tttttggagc tgtacctctt caaatggggt 2434621 tatttctttt cctaaaaact gccccatcgc ttcattatgg ttttctgata taccataatg 2434681 gtcaccatat aatacaataa cagagttgtc gtataacccg tcttccttca gcttttcgat 2434741 aaaccgtttc agcgcctcat cctgataacg cactgtcgga aaatatttat ttagcgtctg 2434801 gctgtttgaa tcatattcat caatcaattg atcctcttca tcaagatcaa acgggaagtg 2434861 gttcgtcagt gtaatcagcc tcgagtaaaa cggctgaggc agatttttca tcagctctga 2434921 ggactgctca aaaaattctt tatccttaag tccccagccg actgaatttt cgtcagttac 2434981 atcatacgag ttaatatcaa aaaacgaatc atatccaaat gagtcgtaca ttaaatcacg 2435041 attccaaaag ctcttattat tagcgtggag caccgctgaa tagtatccgc tgtttttcaa 2435101 aatttcagga gcggccatat attgattgcc cgcattcgta aaaaatacgg cacctcgtcc 2435161 aagcggatac agtgaattgt ccacgataaa ttcagaatcc gaggttttcc cctggcctgt 2435221 ttggtggtaa acattattaa agttgtagct ctgttttata aagtcattca gaaaaggcgt 2435281 gatttcttct ccattcaatt tttcattaat cacgaagctt tgcgtcgact ctaaggatac 2435341 gagaatgacg ttccttcctt ttgcagcgcc gaataagcgt ttgttggcat ccttcgcatt 2435401 agcggttacg tagttttcaa tctccgtcag gctgttgctg tctgccaacg ctctctgtgc 2435461 ggattgcttt gactgaagaa cgccatcgta aatatgaaaa ttaaacaggc taatgttttt 2435521 aacaagcatt tctctgtcaa atgagcgtgt caatagctga ggtctttccg cctcagacaa 2435581 gcccaggttg aagaaataaa cagaagcaac gaacaaaaaa taagccgccc gttcattttt 2435641 cgttgaggga atgtccgatt gaaaagcttt ttgccggatg tgaagccata ttaaaaccgc 2435701 aatatctaca gctaatagga ggtctgtcgg ctcaagaagt gttccgatgc tgcttccgag 2435761 atcacccata ttgctcgttt gaaaaagaac agggattgtt aagaaatcat tgtaaaaacg 2435821 gtaaaaaacc atatttgcca gcaatacaaa cgtgacaaga cagctcatcg cgataatgta 2435881 gcgatttctg tttttgcctt ttaaaaacag gctgaggcca aaaataagca acaaaaaact 2435941 caatgggttg ataaacagaa taaattcctg tgttagattg tcgattttaa tatgaaaact 2436001 ggttttgtaa acagcatacg ttttcagcca catcaataaa atggcaatca gcataaatga 2436061 aatcttcgaa aaaaacgttt ttcgcatttc aacctcctat gcagcacgct caaaaaaatc 2436121 agtctattcc caacattctc attaacacat caaattaaat cttaacctga gcacaacaaa 2436181 aaatcaattt catttacaca attttaacaa ttttgatgtt tcagccattc atttttagcg 2436241 atccaagcgc ctccgataac gccggcatca tttccaagtg ctgcgattga aatatcagca 2436301 gcttgggctg cccgcggaaa cgcgcatttg cggaatgttt tctcgacttt tgatctcagc 2436361 agttctccgg ctctcgatac gccgccgcca agaacgattt tggatggatt aagcgagctt 2436421 gccaaatttc cgagcaccaa accaagatgc ttggctacat aatcaaccac ctcaagggca 2436481 atttcatcat tttcacccgc cgcttcaaac acatctcgcg ctgacaattg ttcggttgct 2436541 tttaaacgtg tcgtcttttt agcatttgct attttttctt ttgcaattct tacaattccg 2436601 gttgctgacg caattgtttc gatacagccc gttttgccgc agttgcaggg cgctccgcct 2436661 tcagggatgc tgcaaatatg gccgatttct ccgccggcgc catttatacc atgtacaatt 2436721 tcaccatttg caatgatgcc gccgccaact cctgtgccaa gcgtcacgag aatgacgtct 2436781 tttgcgccat cacccgctcc cttccacatt tccccgagcg cagcaatatt cgcgtcattt 2436841 tctataacag ctgggatgcc ggtttctgtc tccagatggt ttttcaaagc ataatttttc 2436901 caccctagat ttactgtttc ataaaccact cctgccgcca tatctacagg gcctggtgca 2436961 cccattccga tgtatttgat gatgtgcttc ggtttttgca gctcatccag cttgctgtcg 2437021 attgtttttg caattgtgac agtaatcgtg tcgccggttt tatctgtcgg aacttcccac 2437081 ttatgctgaa tttcgccata ttgattaata aaagcgagtt taatcgtcgt tcctcccagg 2437141 tcaatgcccg caaaccatat ctcgtccatt tttatcacct tagcctttat aaaaatctct 2437201 tccgtttttt gtttgttcca attcttttcg aaggacagct gccgctctgg cccactgctc 2437261 cttttcaatc atgtggttca tgtataattc ctttaattca tccagcataa actcaatttc 2437321 aagctctctg tctccaaaat aaacaatgtg gccaaacgtt tttaacagct gctgcacatc 2437381 ataaaatgta ttcattttcc tcaccatttc ttgaacttaa ctatcataag cgtattcata 2437441 aggaagcggt cagtcaagaa gaaaacgctg acaaaaaagc cagcttcctt tccatattcc 2437501 acctctatga ttctttattg ttttcaattt gccgctgcag ctccttgtag cgctgctcct 2437561 tcggcttcag tttcacagcc gtctggatgg ccttttctgc ttgtgcaagc tcattttttt 2437621 ccgcatacaa taacgctaaa ttgtaatagg aagcatggtc tttaggttct tttttcactg 2437681 ctcgttccaa aagggaaacc gcctgatcat attcgccgat ttgaatatca gaaacagcaa 2437741 gaattttcaa aagatcggca gaggcatctt tttgcgctgc ttctccgttc agcaattctg 2437801 ttacttcttc atactttcct tcctgataca gctcgcttgc ctgctgaatc agcgctgact 2437861 cctggtgtga aggcgaatgc aatccgtaat ataaaaatcc aacagccaaa gcaatcagca 2437921 aaaccgctga caacaatctt tttccaaagg ctccggcttt aggcaacccc agtgctgctg 2437981 cagcgaaaaa gccgccaatc aagccgccga tatgtcctga attatcaata ttcgaaaccg 2438041 caaaaccaaa gcccagattg atgataataa tgacaataat attggttcct atagttctta 2438101 aaaacatttt tcgattagac aaagcaacat acagtaatgc acctaagcat ccgaatatgg 2438161 ctcctgatgc ccctgccgaa ggatacgggc tgaacacaaa actcgcaatc gaacccgtaa 2438221 tgccagcagc cagataaatc agcaaaaatc tccccgatcc atacatccgc tcaaccgctg 2438281 taccaaccga ccataaagcc agcgtattaa aagctaaatg cgctatgccg atgtgaagca 2438341 cgatcggtgt cagaagccgc caccattctc cttgtgcaat caggctgttt tcttttgctc 2438401 caaaagccac cagtgtctcc gtattagtgc tgcctccgtt tatttcgagc aagaaaaaca 2438461 tcaggatctg aagcgcaata aataaatatg taaaagtcgg ttttccgttt tgaaaaaccg 2438521 ccgcttcagt ttttctctgt tcttcttgtt tcagcactag cgaaaggaag cgttctcgcg 2438581 ccatttgcgc gttttcaaac gaagcgtgtt cctctgaaca atcttctgta cgaaatgatg 2438641 gaaaaaccgc ttgaagatca tctcgaagca tcgttcctct aacgatcgcc ggctcaactg 2438701 acacagttcc cttctcaaaa gttttttttg caatctcttc ccagtcatca actggggctt 2438761 ccgttgaaaa aaacacgttc agcagcttca tccttcgtct gcccaattga tgtctgactc 2438821 gttctactcg ttcggcctgc tcttcgatgt ctctaaccat ttcttgacgg aaatcaagat 2438881 cgtgcttata aagacgaact agatcatgag aggacttgtc cggcgcttcc agccatattt 2438941 catctgactc accggcttgt atgacgccat acccgctatt caccaggtgc gccgcaattt 2439001 tccaatatgt atactccagc aaaaacatgt ttaccgctcc aatagttttt tttcattata 2439061 acagctggcg ctccgaaacg cctactgaaa gcaaaaaatc ccgtttttca cgggatttta 2439121 gaaagcttgc tgtataaact tattgcggat aaatggaatt cttaaaaaca aatggataaa 2439181 agaccgcctg attcctggct ggctgagtac agtattcata agacggtagc gattttgata 2439241 aaacatgacg gcagaaaccg cgaaaatggc atatatcaaa agttttttca tgatatccct 2439301 cctgccaata gggtttgtta ttctacctta tttattctcg aataagggac aggaaagtta 2439361 tgaaaaacaa gaaataatcc gatcctctgt tatcagctta tgtaccggga tgtcatgcgg 2439421 cagacggggt acgtgcgcaa acaactggca ctccaaaagc aaagagactg tcttcccttc 2439481 atattcactt aaatagcgat cataatagcc gcctccaaag ccgaccctaa acccgttaac 2439541 atcaaaacaa acacccggaa cgatcatcaa gtcaatttgt gatgggttta cttcttttgt 2439601 tttttcaatt accggctcga gcagtccggc gtacacggtt tcgagctgat catcagtctg 2439661 atatgtgcga aattgcattt tcttcgtgtc cggatggcat tttgggatgc aaacttgttt 2439721 cccttcttcc caagcctgct caatgacagg acgcgtcggt atctctaatc ctctggaaat 2439781 agtgacggca atggtgccgg cattttgcca ctccggcaga gaaaacaagt acttatacat 2439841 acgttccgtt ttttgaagaa tatcttcatt tgataaagca gacagtgcct ccagcgtctt 2439901 ttttcttaat tgtgatttca tctctcatcc ccctcggaat agaaaaaaag ccagaacctt 2439961 tttcaaagct ctggcttttt tcttacacct caaacagcaa agctgttatt ttgtttcacg 2440021 gtgtaacgta gattttttat cacgtgggca atatttttta aattcaacgc ggtctggatt 2440081 gttgcgtttg ttctttttag aaatatagtt acgctcacca cattcagtgc aagccaaagt 2440141 aatattaacg cgcattattt tccctccaaa ctaaaatcat ttacttattc agacttatat 2440201 ataataccac tataatggac ggaatgctag gctgtttttc aatgaattgc tgaattattg 2440261 aagatacgct cataaagctg caaatatgat gacataatga gtcgggggtg gtggagcttg 2440321 aacacttgtt gtctgccagc ttcttttatc cggcgggctt tttcccggtc ttttaaaaaa 2440381 ctgtccagca gatcagcagc ttcctgtacg agcgtaaaat cagcgatgat tgccgttttg 2440441 tcatgaaccg cataatcaca aaaaccacct gactgagaaa cgacagtcag cacaccttgt 2440501 tccatgcttt cttgcgcggc aagcccaaac ggttcataag aactagggaa aacagccatt 2440561 tcacagtgag acagtaacgt tctgatatct ttcctattta gaaacggcag aaacatgacg 2440621 cgatccttca ggttatatgc cgcagccaat ttctcatagc aggacagaga cggcccctcc 2440681 ccagccagca ctagatagag gtcaggctga cgctgcttca agatggcaaa cacctttaac 2440741 agctgcgata atcctttttc cggaacaaac cttccatatg aaaagaggaa tcttctattc 2440801 atgcttctcg ggattttccc cttctcttcc tccatagatg cagggcttgg gataacggtt 2440861 attttcttat gtgccgcctt atcaagagac cgcttcataa atgtgcttaa tacgatcaat 2440921 gcatcagcgg attctataag gagccgttcg gtcatgagcc tgtatgggtg tggggcttct 2440981 cggcacacct tcttcctttc gctttcaaga ccgtggattg tcgcagcaag cggaaggcca 2441041 agccgttgtt tcaaatactg ggcggcaggg gcagttgtgt catcatgggc atgaatcaga 2441101 tcaaagcgtt tattgtgtga taacacatgg cgaaccattg taaagttagc atcagctatg 2441161 taatcttcaa acttcgcata cgaaaacagc tgcccgctcg gagtaaaaac cgtaatgttg 2441221 atatgagggt ttaaatagga aatgaggcgg tttaaatgga caccgagccc gcttttcggc 2441281 tcatcgggat gttcgggtga aagcatgaga atgttcaccg ttctttttcc cctctcccat 2441341 aacaggtgta tgcagaaaat tgcgcctccc acctggtgtg cgcttcttca atctgaaaac 2441401 tgtttatatg acgaatccca ttttcatcaa gatagatgtc gtctgtaccg gcaagcttga 2441461 gagagacatt cattgaattc acaattctgt attcagcccg atatacagca tcaccagccg 2441521 cctgtctaat cgtccattct cctttatcat acgttgtgcg ttttgtcctg acagcttcaa 2441581 tgtcttttct tttgatgaca atgcgcaatt cttttatcat atcctgcgtt ttttcgaaaa 2441641 ggaccgcttc agccagccgc attgtttctt ctgagatttc ccagcttacg gtcaaggtgt 2441701 gagcgttttg aatgattatg tcgaatgtgt ccctaaaaaa ggaaagctta tgtcgtatat 2441761 tatagggaaa tgggtgttta tccatggact cctaacattc tcctttccaa tcgttcactt 2441821 cgtgttccta ttaaaccatt acatgaagaa gaagcgaaga aagatttctc gacaaaatct 2441881 cgtttttttc gcgaattcct ttagaaacta ttggttttat ggtataaaaa agaaggataa 2441941 aaaaagaata gaaggtgatg aaacgtggaa attgctatta ttgcgttgtt tatcgtcagt 2442001 atagcgctaa ttgcattctc atattctcaa agagacccga tgaaagatgt agaacaggag 2442061 ctcgaaacac tgcagctttc tgcgatgcag gaaatttaca agctcaaaaa gaaaatgaca 2442121 gtgcttgagg aagaattact ggaaacaaac cttgtcattc gcaaatcaaa gcagaacgac 2442181 atcaatcaaa aaatcgctaa acaaatactt tctaaatata ataacggtat gtcagctgaa 2442241 gcgattgcta aagctgaaca tgtatcagtg gaagacgtga atacgattat caaagataat 2442301 gagaaggtgc tcgtatgaca aaacggggca ttcaggcatt tgctggcggc atcattttag 2442361 cgacagccgt tcttgcagct gttttttatc tgactgacga agaccaggcc gctgctgtaa 2442421 aagataataa aacagtaacc gaacaagacg tgaacaatta tcttgattct aaaaaattgg 2442481 tttctgtcaa ccgtgatgaa tatcaaaaac ttctcgattc aaaagagaaa tccttaaaca 2442541 atgacagcgg ctcagacacg aaatcagaca aagtcaaaac ctacaagctc accattaaag 2442601 acggcatgag cacggcggat gtatctgcta ttcttgaaaa agagggcatt atctcttcgg 2442661 ctcaagactt taatgactat gtcattgatg ccggctatca caaagaaatt cgtgccggcg 2442721 agtttaaagt aaaatcagac atgagtttca aaaagatcgt aaaaacgtta acacgataaa 2442781 aaaacaggct gactcagcct gtttttttca tccaaacttt cctgaaatgt aatcgagcgt 2442841 tctttggtcc ttcgggttag agaacatttt attcgtattg tcgcattcaa caagctcgcc 2442901 catgtagaaa aaggcggttt gatcagaaac ccttgctgcc tgctgcatgt tatgcgtgac 2442961 aatgacaatt gtatatttat ctttcagctc tagaatgagt tcttcaattt ttctcgttga 2443021 gattggatct agtgcagatg tcggttcatc catcagcaaa atatcaggat tggtcgcaag 2443081 tgctctggcg atgcaaagac gctgctgctg gccccctgac agcgaaagag cggacgtatg 2443141 caatcgatcc ttcacctcat cccataacgc cacgtctttt aatgactttt ccacaatttc 2443201 ctgaagcttc ttcttatttt tggtgccgtg gactctcggt ccgtaagcca cattatcaaa 2443261 aatagattgc ggaaacggat tccctttttg gaataccatg ccgatatttt ttcgcaaatc 2443321 cacgatgtcc actttatcct ttaaaatgtt gctgccatta tagttcagct cacctgcaag 2443381 ctttacattc ggcgtcattt gaatcattaa attcaatgtc ttgataaagg tcgatttccc 2443441 gcatccggat ggtccgataa tcgccgtaac ctcattttca taaatgctca aattgatatt 2443501 ttttaaagca tgatgctgcc cataccataa gttcattcca ttgacttgat atacttcctg 2443561 tttcattaca gcttcggtag caatactcat tgccgccctc ctatccgaat ttcccgttaa 2443621 tataatcctc tgtcttttgc tttttcggac tcgtgaaaat ctgttcggtc tgtccgtatt 2443681 ctacaagctc gccgtttaaa aagaatgccg tccggtcaga aacccgcaga gcctgctgca 2443741 tattgtgcgt gacaataata attgagtatt ctcttttcaa tcctgtaatt aattcctcta 2443801 tttttgcatt tgaaatcgga tcaagcgctg aagctggttc atcaagcaga agaacagccg 2443861 gcttcatcgc aagcgttctc gcgatgcata aacgctgctg ctggccgccg gataacgaga 2443921 gtgcggatga atgtaaacga tccttcacct catcccagag cgctgctttt gttaaacttt 2443981 cttccacaat ttcatctaaa acagctttat tccgctctcc ggcatatttc aatgcatgtg 2444041 tgatattcgc atagatcgat ttcggaaatg gatttggttt ttggaaaacc attccgattt 2444101 ctcttctcaa gctgacaacg ttaatattgc cgcccaatat atttaatccc tcataaagga 2444161 tttcaccttc cgctcttgca gatggaatta aatcgttcat tcggttaata tttctcaaaa 2444221 aagtagattt tccgcatccc gacggcccaa ttaaagcagt caccgcattt ttttcaatat 2444281 ccatgtttac atgatgaacg gcttgtttat ttccgtaata aatggacaga tctttgacct 2444341 caagcacgtg gttctgcttc ggaacaataa cagctcgctc aggtttttct tttaccattt 2444401 gttcagacat gtttttcgcc tctttccgtt ctaatttgcc gtaagctttt tgtagatcat 2444461 cgtgccaagc catctcgccg cgagattaaa cacaagaaca gaaatcacca gcacggcaga 2444521 accaccgttg gcaatcgctt cagcatccgg aatcattcct tgtgtattga cgttccaaat 2444581 gtggaccgca agtgtttcag cgggcctgaa aatattaagc ggtgatgttt ccgaaaacgg 2444641 gttccactcc gtaaaattaa gacgcggtgt tgtcaggcct gccgtaaata ataatgcggc 2444701 cgcttccccg aacacccttc ctgacgctaa aattgctcct gtgatgatag aaggaatcgc 2444761 acttggaatt aaaactgttt ttacggtatg ccagcgtgat acacctaaag cgagagaggc 2444821 ttccttcaga tctttaggga ctgaacggat cgcgtcttct gtcacacgca ccatgacagg 2444881 aaggttaaaa acagttaacg caagcgctcc gcctatgatc gtataacccc agcctgttaa 2444941 gttgacaaac atcaataatc caaacatccc aatgacaata gacggaagag atgaaagcac 2445001 ctctatacat gttctaatga agtcagttac tttgttatta ggcgcgtatt cagccatgaa 2445061 gactccgccg cccacaccga gcgggattgt aatcagcatt gtaataaaca aaatataaaa 2445121 ggagttaaac agctgatctc gtatgcctcc tccagctgca atggcgctcg actttgttgt 2445181 aataaattga aaactgagct gagaaacacc gtttataata atataggaaa acaaacctac 2445241 taaaatggca gcgataatgg ctgcacacaa accaaacatt ccggtcgcca gtttatctgt 2445301 tattttgcgg ttcattacac tttcctccta gatgacaagt agcgaataag caggatgaac 2445361 aagaatgaca tcaccagaag cacaagcccc attgaccaca gcgtattgtt ttcaacactt 2445421 ccgtatgtgg tgtggcccat attcagcgtg atgatcgttg tcagcgttcc cgcagtgtca 2445481 aacgggcttt ccggcaatac tcttgtattt ccaatgacca tctgaacagc caaagcttca 2445541 ccgaacgccc gagccatgcc taacacaaca gctgtcatca atgttggaaa agctgcaggc 2445601 acaagtactt ttctgatcgt ctgccatctt gtggcaccaa gcgcgtaaga accctctcgt 2445661 aaactcttcg gaagagaagc cattgcatca gcagaaatcg atgtgatcgt cggcagaatc 2445721 atgacggaaa ggacaatcgt tcccgccaat aaactgtgcc ctgttccgct cgatttgaac 2445781 tgggcgataa acggcaccaa tactgtaaga cctatgaatc cataaacaac agatggaata 2445841 ccgactaaaa gctcaatcac cggctgcagc actttctttc cccaattcgg ggcaatctct 2445901 gtcataaaaa tcgcacctgc aatgccaagc ggcgcagcga ttagagcaga aagaatcgtt 2445961 actgcaaatg agccaaaaat aaatggcagc actccgtatt tcggatcact atctgtagga 2446021 ttccaattta agctcgttaa gaattcaatt gggcttacac catttacaag aaaagattgc 2446081 agccccttaa cgccgaggaa aatggtaatc gcaacagatg ccgcaatcat aatcagtgca 2446141 caagctgtga ctatcattct tccccgaact tcatccaatt gccgattttg cctagagctg 2446201 attaagcgct cgctcacaga catattttct ctattgttta tcattgtttt acactcctat 2446261 gaatgtgtta agaggagaaa cggttgtccc cgcactcctc tttttattaa gatcagcttt 2446321 gcttcccgtt ggcatcacgt gtcactttca tatcagtaac cggaatgtag ccttggtcag 2446381 taacaatgct tttttgaatg tcttcactct ttagataatc aagaaattct ttagctaaac 2446441 ctgtcgcttc accttttgta taagaatgtt gataagccca gatcggatac tcgccagttg 2446501 ctacattttt cgcttcaggt ttaacaccgt caatagatag agcagttact ttgtcatctg 2446561 ttaaatatga gaatgcaaga tatccaatcg ctcccggagt atcagcaatg atctttttca 2446621 ccgtgttgga ggaatcttca gtaatgcctt ctgcaggctc cgctccgtca agcgcatatt 2446681 tcacaaatgt agcacgtgtg ccggaagaat cagggcggtt tacaagtgta atcttttggt 2446741 ctttgccgcc gagctctttc cagtttttga ttttgccagt gaagattttt ttcaattcat 2446801 cttttgaaat atcctttaca ccagcatcag ggtttacagc tgctgccata ccaactacag 2446861 cgacttgatg atcgacaagc gcttttgcat cgatgccttc tttttcttca gcaaaaacgt 2446921 ctgaattccc gatctgaaca gctccttcag agacttgaga aagccctgtt ccagaaccgc 2446981 cagcttgtac ctgtatatca gcatcagggt tttcttccat aaatttttcc gcggctgcaa 2447041 gtactagtgg ctgcattgcc gatgaaccag aaatggttaa agaacctgat gccttttctt 2447101 ctccttttgc agaatcgcta ttcgattttt tactttctcc tgcatttccg catgcagctg 2447161 caatcatcat aaaagcagcc atcagaagca taagcaccaa tttgtttttt ttcatttcct 2447221 gaattccccc tgcgtataat gtgtaatttg tcctacacgt atagagtaaa ggttctatgt 2447281 aaaaagggtt tgaaccgaat gttaaggttt tgtaaatcag tgcgtttttt gtataaaaaa 2447341 aacgcccaca tcatgtgagc gttttttttt agttatcaga agacgttgtg ttttctgcat 2447401 tttcttcaat tttgtcttta ttcttttgct gagtaccttc tttgtcctgc ttcgatttca 2447461 gctcaaaata tttatccatt acttccctgc cgatttcgtt tgtaattgag tatctttgat 2447521 tgtaatcaat gtaagtccaa ggaactacga cagaaatagc aatctcagga ttgtcagctg 2447581 gtgcataagc cacaagcgtc gtattataag tgtctgttcc tgtttttgat ttatccggtc 2447641 cgtcgtaaaa tgattgggct gttcctgttt ttgcagctgg tttatacgat gctgaagcca 2447701 gttgacctgc agctgtccct ttagtggcaa cccgtctaaa accggcttgg acctcttcaa 2447761 tatagctact cttcatatcg actttattca atacttcagg ctgaacagaa tcaacgactg 2447821 cgccgatccc ttttttcgca tttgaatctc tgacttcctt tacaagctga ggcttcatgc 2447881 ggtagccacc atttgctatg gtggagacat attgagccaa ttccagcggt gtataagtat 2447941 catactgtcc aatggcgaaa tcaagcaaga aaccagataa tctgcttgta cctttatatc 2448001 ccgtcatttc atttggtaga tcaattcctg tttttactcc taatccaaat tgactgaaat 2448061 aatttctgaa ggtatcaaat gcagaagtat ccaaaggcaa tgcttggtga ggtttatatt 2448121 cacctttacc aactgcaatt gctgttttaa acataaaaac gtttgatgac ttctctaatg 2448181 cagtttgaat accaaccggc cctaagtttt gccaagattt tttccctctt ttatcctggc 2448241 cgatatacaa tggttcatcc ttaaatacag tattcaaatt aatcgctcca gtttgaagac 2448301 cggtcaaaac ggttgcacct tttacagctg atcccatagc gtaggatgaa gtcatggctc 2448361 ctaatgcata atcatcaaac ttataggctc cattttctcg tttaatctgc ttccctgcca 2448421 ttgtcagcac ttcgccgttt ctagggtcca tcatgacaac gaatgcacga tccaacaatt 2448481 cggtactagg tcttgcttta gcagctttaa gttttttctc aataattttt tccactgatt 2448541 tttgcaaatc aatatcaatt gttagtacaa gatctttccc ggctttgcct tcagataccg 2448601 tttttgttcc cgtgacattg ccttttgaat ctgtgatatt ttcgactttt gctttttggc 2448661 cctgcagaag gctttcatat tggtattcca gatagctttt tccgaccctg tcatttcggc 2448721 tgtagccaag cgacagataa tggtcgagca agttggacgg caatccttca ttagagctgg 2448781 aaacacttcc gagcactgag cgaagaaggt ttttataagg atattcacgt tcccaatcgg 2448841 acgtgacatc aacacctggc agttcgtcta aatgttcact taccactgcc atttccttcg 2448901 ctgatacatc ttcgtttttg atatattgag gggtcaatgc atagcccgaa tccatctgtc 2448961 ttttgatagc aaggatctgc atatctttat ccgtcaattc attcagctgc ttatcagtaa 2449021 tccgttttag ctgaagctgg tataaatcgt catcggatat ttttttgtct tcaacctgct 2449081 gtctttcttt agagctaatg agctttttcg cttctttcgg tctagtcaaa atccaataat 2449141 cttttttatc ccgttctgtt actttttttg tatcgacttt gatcatgtca gacagctttt 2449201 ttgcgatctt taagcgctgt tcttgcgtgg tcgatttaga tctcgtgtat gtgattgcat 2449261 ttaaagcctt atttgtcaca atggcattaa agtttcgatc ataaattttc ccgcgtggta 2449321 ccgctgagct gacttcactt tgttcctgct tattcgcttg gtttttgtaa tcatcacctt 2449381 gcacgatctg cttgatgccc agttccacaa taatccaggt aaatataaca aaggcagcta 2449441 aaaataaaat attcagccgg atcggaagcg acttcttttt ctctttatga ttttgctttt 2449501 ttggtttatt tctcctcata acatcacctt ttctatttac agaaagaaaa gacactcaag 2449561 taagagtgcc agttttcatt ttaaaggttt tttcgacttt tttctacaga taaccccttt 2449621 ttggcaaaaa aattatctct cgccttttaa aagggtcggt tctgttaccc gtttttggcc 2449681 gtcttcttcc atggtttcat tttccccttc tttctcctta aaacgaatat ccttgacaaa 2449741 gtaataaatc aaaggatgtc ctatacccaa tatcgcaagt gacaaaggaa ttcccacatc 2449801 ctctttcaga agggccacaa tcaggagaaa gcacaaaatg gaaacaattc tgccggcgtt 2449861 caagaacatt tctctaagca cgatatattc aattcttgct tttctggcat gcctcgcgcg 2449921 ccctatcaca tcatatgtaa gtgatacata tggcacaagc aacagaggat agccgatggc 2449981 aataaaaacg ccgtacgtta ataatgtcga aaagctcata tggaacagaa tcaaaaacag 2450041 cgcgccatac aaaataagtc cgcccagcaa aatcgatttt tttctcgcct ttttcttaat 2450101 cagcctggat gcaaagtagt aggcaaagaa ggaaacagct gaattgacaa gaccgaatgt 2450161 accgagagca agctcgctgt ttgtctcaat aaatacaaac acactgatta aaaagacaaa 2450221 aatcccttct ctcaaaccct gaaaaaaatg cgcattcgtg attctccgcc aattcatatt 2450281 gctatggcgc tctccaaata ctttgctcag cataaaacgg ccctttgatt ctctccgttt 2450341 taagaaaaag ctcatcacga cagccagggc aaataaactg agggagagac tgaaaatcac 2450401 tgtataaccc gtattatttt caagccttga gatcacgaat ccggctacaa tcgggccgat 2450461 cattcctgca gaggaagaca gaatgcccat aaacccgttg aaaaagtctc gtgtatccgg 2450521 ctctgttatt tcaaaggtca gcacgttaaa cgctagccaa taaaagccat agccaactcc 2450581 gagcaccgcg ccgattagca cgaggcggct ggccgccgtt tctccggcta aaagcacact 2450641 taaataaaag gcagctaaaa aaatgacgcc gaaccttaaa atgaataccc tgtctatttt 2450701 tttggctaac cgtccagcca aataaaaggt tatcggctgc attgtcacaa tggataaatt 2450761 atatatcgcc aaatcaataa atttccctga ctgcttccaa agatacacat taacaaatgt 2450821 attggacagt gcaattccca gcgagtaaag cccgccaatg gtcagcagaa agagtaagcc 2450881 tttgtttacg tctacatcgc ctatcacttt ttttagtttg ctcattactg actccccttt 2450941 actatccctt agtctgtctc actcaaaccg agatatgtaa aaagaagaca taaaaaaaca 2451001 aggtcccata atgaggacct tgtttgtgcc attattttgc ttcgctgtat agacgagcca 2451061 cttcgtccca gtttacaaca ttccagaaag ctgaaatgta atcaggacgg cggttttgat 2451121 agttaaggta gtaagcatgc tcccaaacgt caagacctaa gataggcgtt ttgccttctg 2451181 aaagcggaga atcttggttt ggcgtgcttg tgatttcaag tttaccgttg ttcacaacaa 2451241 gccatgccca gccagaaccg aagcgtccag ctgctgctgc tgcgaattgc tctttgaatt 2451301 tgtcaaagct tccaaataca ctgttaatct cttcagcaag cgcgccagtc ggttcgcctc 2451361 cgccgtttgg agataaaagt gtccagaata atttgtggtt cgcgtgtccg ccgccgttgt 2451421 tgcggactgc agtgcggatg ttttcaggaa cagaatcaag atctgcaaca agctcttcaa 2451481 ctgatttgtt ggcaagagca gtgtttcctt caaccgcttt gtttaaattt gtcacgtatg 2451541 tgttgtggtg tttcgtatgg tgaatagtca tagtttcctt gtcgatatgc ggttctaaag 2451601 catcgtacgc ataaggtaat tctggaagtt cgtaagccat gataattcct ccttagtata 2451661 tatgtactga aatgccgctt cacagcgagc ctttcttcat tcaatgtaac aaaagaatgc 2451721 tttgtaatca atgaaaaagc tcacgatttg gctcatttca gcggacatat ttcactttaa 2451781 ccgataatct gccccattaa acctgccgcc agcatttctt ataggaccgt ccataaaaag 2451841 taaccgatca tcaaaagctg tatgatgccc tttgcaataa cccctgttaa aaaaccaatg 2451901 agtgagccga ggccaatttt aaacgctgac tttaagtcct tctgatggac gataagttct 2451961 gcgcaaacag ccccgataaa cggccccaat atgatccctg caaccggaat gacaaaaggc 2452021 ccgattaata aaccgatcgt gcttccccat atggcagctt tgcttcctcc gaaccttttt 2452081 actccaagca gattcgacac gtaatctgct gcgaataata ctgcggcaaa aactgcctca 2452141 acaagccaga acatataaga atacggactg aatgaaaata aaaatccgta caatacaaat 2452201 ccggcaacaa taaatactac gctaggaata acaggataca ccagcccgat aaaggcaatg 2452261 ataaaaaccg ctgcaatcaa cagccaatac aacatatcca tagcttccat cctcccattt 2452321 tactctgtct tcttcatgtc ttccttgtat tcacacgcat gcaacgatac aataagcaac 2452381 atatattagt ttagctagga agtgaagata gtgaatgtgt ttcagctttt cattaaaagt 2452441 acatactctc cccgtgatat tgcaaaaaca agatttcaag gaatcggaaa agcgattctt 2452501 tatgtatttt tgctctctgt cctgtttgca atccctaccg cttattatgt aagtacaggg 2452561 accgtaaaat caatgaacgg ctttaaaact gttttaaaca aagatttccc tgatttcaca 2452621 atttcaaacg gcaaacttca aacggatgag aaaaaagcca cggaatctca ggcaaatggt 2452681 ttcgttatcg tgttcgatcc gacagactcc tatggcactg aacaaattga agcaaagcaa 2452741 aacgcaatcg gcatccttca gaacaaattt gttttggcca ttgacggaca agcccaagaa 2452801 atgtcttact caatgatgcc gtcagagtta cagaaaaaag atgtcattgc aggtttaaac 2452861 caaaataaag cgatgattgt aactgttctc tcagctctta tttttctcgt aacagcagcg 2452921 ggaaaattta ttgaagtatc gtttttagcg cttatcgggt taatcattaa gaattcgcag 2452981 aaaaaacatt tatcctatca tcagctctgg aagctttctg cttattccat cacactttca 2453041 actgtattct ttacaatcat gcgggcacta gaagcaaccg taccaagtga atttttgctg 2453101 aactggtttg tcaattttgt catcctgttt ctcgttttaa aagagattcc gtccaaaaaa 2453161 gtaattaata aaagttaaat tatatttatt tttatccttt aagtagagag tgtgaaagca 2453221 tttgcattaa ctttttactt aagggatatt taataaaatg tatagagctt aaacagatac 2453281 atttataaaa aaagctctac aattactcaa gaacaagctc tggacaataa tatcagaagt 2453341 agtaagatgt aacatgaaag aagttcttaa cagcatttga catatgtttt taacaaaata 2453401 agaataatgt taaattttaa ctaatagact agttaaaatc atatggcaaa atattttgca 2453461 tcctttcaca acatatttac ataagatagt tgctatttaa aaagccaggt accaataggg 2453521 cacctagctt tcagaattaa atcatcaaca agttagaatt atcttctttc cttctattct 2453581 cattattgaa ctgttatctt ttttgtgggt ttatgtatac aaatgcagct cccttagctt 2453641 tccccttata tactgataaa cctactgccc aaggtgttcc tgtcggtttt ggtaatttac 2453701 tgaagtaaaa ctttttggtt ggagttctac ttgaaaagta ccctgaatat tgcgggccaa 2453761 tgtccccacc ctcaactata gatacaccaa agctcttata atttagttta ccgcattttc 2453821 catttgtttc ggcgtaagca tcaatagatg ttgcactctt agtatatgta taagcatctg 2453881 taataactct tattttacaa ccagaaatac cacttaccgg ttgccaacca ctgcttgcag 2453941 cctctgcttt ttctttaggt gcaactacca aagttaacat tagtagcaaa attaaaaaca 2454001 cagaaaattt tccttgcttc attttgtaga tcctccttta aactattaca taattatcct 2454061 aacagatcca ttgttcattg taaataatgg aatacgagtt ttatattata aaagcctctt 2454121 tttgatctaa ttttgcacta ttttctattt tctatctgaa gttaatgttt agtcgaagaa 2454181 atcctgtcaa aaaagcgcct gtataaaaac cgagcattcg cagtctcttt tcttttgtca 2454241 tgaatcgaaa tggacaagca tactatggta taaaatttcg tatgcgggag gaaaagcgat 2454301 gaagcgtctc accttagtat gcagcattgt ttttatactt tttattcttt tttatgacct 2454361 taaaattgga accataccca ttcaggacct ccctgtctat gaagcatcag caaaaacggc 2454421 tgtacaagaa ccggcttata aaacggtgaa ggtaaagccg ggtgatacgg ttatgtcgat 2454481 agtcggatca gcaggttctc cggatgacat tgtaaaggat tttgaagcac tgaatccaaa 2454541 tgtgaaagct aacgccattc aagccggaac agcgtataaa ttcccggtct acccttaatt 2454601 taacgttaat ttcttgtcag ttcggcgaag acactgttac aatgtaattt gtaaaataaa 2454661 ttcacataaa ccatactaga attgttatat ctagaagcgg caactacaat taaggagcga 2454721 ttgcaagtga gtgaaatcac acatcgtaca aaaacgcgtc ccgtcaaagt gggaccttta 2454781 acaataggcg gcaacaatga agttgtcatc caaagcatga caacaacaaa aacacatgat 2454841 gtagaagcaa cggttgcgga aattaaccgt ttggctgaag ccggatgcca aatcgttcgg 2454901 gtagcatgtc cggatgaacg ggcggcaaac gccattgcgg atattaaaaa gcgcatttcc 2454961 attcctctcg ttgttgacat acatttcgat tataaacttg cgttgaaagc cattgaaggc 2455021 ggcgcagata aaatccgaat caaccccggc aatatcggcc ggcgcgaaaa agttgaagcg 2455081 gttgttaaag cggccaaaga caaaggcatt ccgatcagaa tcggagtaaa cgccggttca 2455141 ttggaaaaac ggattttaga aaaatacggt tatccgactg ccgatggaat ggtagaaagc 2455201 gcacttcatc acattaaaat tcttgaggat cttgattttc acgatattat tgtcagcatg 2455261 aaggcctctg acgtgaacct tgcaatcgag gcttatgaaa aagcagcgaa agcgtttgac 2455321 tacccgcttc acctcgggat caccgagtca ggaacactgt ttgccggcac agtaaagagc 2455381 gcagcaggac tcggcgccat tttaagcaaa ggcatcggga acaccatgcg catttcacta 2455441 agcgcagacc ctgtagaaga ggtaaaagta gcaagggagc ttctgaaatc tttcggctta 2455501 gcctccaatg ctgccacgct catctcatgc ccgacttgcg gccgtattga gattgatcta 2455561 atcagcattg ccaatgaagt ggaagagtat atttctaaga taaaagcgcc gattaaagtt 2455621 gctgttctcg gctgcgctgt aaacggacct ggtgaagcga gagaagctga tatcggaatc 2455681 gccggcgcac gcggtgaagg gctgctgttc cggaaaggga aaattgtccg taaggttcca 2455741 gaggaaacga tggtagaaga actcaaaaaa gaaattgaca ttcttgctga ggaacactac 2455801 gcaaaacttg aagctgaaaa agcaaaatta aaagaagaaa cacaaaaagc ttgacgggaa 2455861 cccgtcaagc ttttttgtgt tagaaaaatg gaataataaa tattccaagc actaatgaaa 2455921 cgacaccgat acccattgcc caggctccaa ggccttgagc acctcttctt cttgcgatat 2455981 agccgacaat aataccagca gctcccaata aaacaggcag tacaaacaat gaaatgatgg 2456041 acaaggctaa agcgatgtac cctattcccc gtccttcatt gacattgccg ccgctgcgat 2456101 cattgtcttg gtcattgctg cggtcagcag cacgataagg ctctgcgatt tcagcagctg 2456161 tttcctcaaa aaaaccgtca ttgtcgcggg taatatttgt cccttcagat ccatgatcaa 2456221 catagtaact gttgttatca cgcttttcgt aatcgtttgc caccttcaat tcccccttct 2456281 gttttattaa aggagctttt atagtttgat ccattttgcc tgattcatgt ttgctaaact 2456341 tttctgttaa tgtcaattgt ttatgttaca cttgaaggga tgaaactgaa ggagtgtggg 2456401 catgttacgc ttaggaatag atattgacgg cacaatcacg gctcaggata cattcgtccc 2456461 ttatttgaac cgttcgttta atctttccat ttcattaaac gatatgacgg attatgattt 2456521 aacaaagctg ttaaacatta cccaggaaga attttgggat tggatgaatc aaaatgaagc 2456581 gatcatatat aaggaagcat tgcttgcaca gcatgcgaaa cagtctctcg atcttctcaa 2456641 agaggagcac aagcttattt atattacagc gagacggact catttaactg atattactta 2456701 tgaatggttt gacagacaaa acattcatta tgaccacatc gaacttgttg ggggtcatca 2456761 caaagttgaa gcggtcaaga atcataacat cgacctgttt tttgaggatc atcacgggaa 2456821 cgccatgatg attgcgaaag aagccgggat accggtgatt ttgttcaatt ccccttataa 2456881 tcagcttccg attgattcaa acatcatcag agtaaacaac tggctagaag ccgttcaatg 2456941 gatgaacaac aacaagcatc acttaatacg cgtcaataac tgaaaaagga gcccaaaccg 2457001 ggcccctttt tcatatatac gcattttacg cagtagtgtt ttcttggttt tccgctgtac 2457061 aatcagggca tgtgccataa atctcaaatt tatgcccgct gacctgatag ccatccaaat 2457121 catcacaaag cttgtccatc ggacatgatt caatttcctt tgttttgccg caggcaagac 2457181 aaataaaatg atggtggtga tgggtgaatg aacacttaaa tcggaagagc ttttcaccgg 2457241 acagctcagt tgtttccaaa atcccaagtt cttcatataa agaaagattt ctgtagattg 2457301 tatcaaagct taagcctgga taatcatcat tcagtgcaga cagtacgttt ttagcggtaa 2457361 gatatctgtc tgaatcagca aaaagctgca gcatatcctc ccgtttgttt gtatatttat 2457421 atccgttttc ttttaatagg ttcagcgctt cttggacgtt catgaagggt cccccttttc 2457481 gctttgctta agaacgtatc acatgtatga aaaagaaaat ggcagctgtc tgtccagcaa 2457541 gccattttct ttactgcaga taaaattata cccataaaat gaataaaagt aaatgaaagc 2457601 ctagtggatt gcgtttttga attttccgcc tctcgtttca tgagtattca taattgttat 2457661 gaatgcattt tgatcaactt caaacacgat cgatttgagc tttgtcactt ccagccttgt 2457721 gacaaccgcg taaattacgt ctttttcttc gtccgtatac ccgcctttcc ccttcagctt 2457781 cgttgtgccc cgaccgagac ggtgcaaaat cgcgtcggaa atctcatcat actgctcaga 2457841 cacaataatg acagcttttg tttcatcaag cccttggatc acggcatcaa tcgttttcat 2457901 cgcaatataa taagtcatga atgagtacat cgcttgctca ggaccgaaca caaaaactgc 2457961 ccaaatgaaa atgaacacat tgatgaacat aacgaactca cctacagaaa acgggagttt 2458021 tttggtcagc aaaataccga gaatttctgt accatccatt gaacctccat ttcgaataac 2458081 aagcccgacg ccaaagccga gtaaaagacc tccgaacaca gtagccaaaa taggctgggt 2458141 tgtaatggct tctacatggt gaagtgagga ttcaataacg gcaagcccga caatccctat 2458201 aaacgtagag actagaaagg tcttaccgat atatttatat ccgaagatca taaaaggaat 2458261 atttaatatg acaacgaaaa aagcgaaatt cagaaagggg tttgacataa agaggtggtc 2458321 taaaataaga gatacaccga taatcccgcc atcaataaaa tcattgggga ttaaaaataa 2458381 ttcaatactt acagccgcag atgcagctcc taccagaatc ataaagaccc tgaaaataaa 2458441 atgggtaaat gtttctttct tatgttgttt tgttggggtc ataaaatctc ctttcctgca 2458501 ataactattt taaatacatt ataaatctat tttaccatta aacactgaca cattttactg 2458561 atttgcccat acattaagtc tggaggtgga atgaccgatg attttatttc aaagaattat 2458621 tttgcagcgg cttaatcagg ctactgctga tgatttgctg aagtactcaa aacaatacgg 2458681 aatcagctta acaagatcgc aggccgttga agtagcgaac ctgttatacg ggaaaaatgt 2458741 aaacatcttt aatgagagtg aacgaatgcg gctgctgaaa caagtagaga cgattacatc 2458801 gaaagaaaca gctcaaacag ttaatgaact attcaaacaa tttacaagct aaaaaatggg 2458861 ggtgttatcc cccatttttt attgctgtaa aatcttttca agcaatgtat catcaaattg 2458921 tttttctttc agcatttcaa tctcaaaacg gtatggcggt tttttgttct ttttatcttc 2458981 accgacgtat ggtgtttcaa gaatttttgg aatgtctttt aactgctcat ggtgaacaac 2459041 atattgcagt gcgtcaaaac ctatttcacc aaagccaata ttttcatggc ggtcttttct 2459101 cgcacctttg acatttttgc tgtcattgat atgaagcact ttaatacggt caatgccaat 2459161 gattttatcg aactcattta gcactccgtc aaagtcttcg acaatgttat acccggcatc 2459221 atgtgtatgg cacgtgtcaa agcacactga cagctgctca ttgtgtgtaa cgccttcgat 2459281 aatctgcgca agctcctcaa agcttctgcc gcattctgat ccttttccag ccattgtttc 2459341 taatgcaatc tggacatttt gattcggatc aatcacttca tttaagcctt caataatttt 2459401 tttgatgccg gcttcagctc ctgcccctac gtgagcgcca ggatgaagga caatttgctt 2459461 cgctccgatg gccgctgtcc gttcaatttc tgaacgaaga aaatcaacac ccagctcaaa 2459521 agtggacgga tttgtcgtgt tgccaatatt aataatataa ggcgcgtgta cgataatctc 2459581 gtcaatgccg ttttcttgca tatgtgcccg gcctgcttct atatttaagt cttcaatttt 2459641 ctttcggcgc gtattttgcg gtgcgcctgt atagatcata aacgtattcg ccccataaga 2459701 gactgcttcc tggcttgcag ccagaagcat atgttttccg ctcatagaga cgtgtgagcc 2459761 tattctcagc aacaggttcc cctactttct tttcttagat tggtttcttc tctgtttttt 2459821 cttgattttc tccatctcat agctcatttt ctttttatac ccaggcttaa ccttcttcgg 2459881 ctttttcacg agacgatgag caatttcatc cgcttcattc ggcgtttttt tacgtttttt 2459941 gcggcgctga cggtcatcgc cttttttcca ttcgcccttt tcaagctcta agtactcaaa 2460001 ttcgatgccc attttttcaa gtcttactaa tgcatcctca tcagtaagct cataaatggt 2460061 catcgcttgt cctgatgagc cggcacgagc cgttctgccc acacggtgaa catagaaatc 2460121 gagatcatcc ggcagctcat agttgataac atggctgaca cctttaatat caatacctct 2460181 tgcggcaagg tcagttgcaa tgatatatgt gaattccaaa tcattgatct gcttcatgac 2460241 ttttttccgc tcacgtggtg ttaatccgcc gtgcagcaag ccgattttca tgcctttgcc 2460301 agtcagatac tgggcaatat ggtcagccgt atttttcgtg ttggcaaaca caatccccag 2460361 gtatggattc agatgcgaca tgatgtcaaa aaggagcttg tccttgtcac gatgtttcga 2460421 aggaatgagg atatgctcga ttttcgcagc agtcacctgt tttggctcca catgggcgta 2460481 tttcggattt tccatgtatt tcttcaagaa tggtttcagc ttttccggta tggtcgctga 2460541 gaacacaagc atttgcagat cctcaggcat gcgggaaccg atgtaatcta catctgcaag 2460601 gaatcccatg tccagcatta aatccgcttc atcaataaca agagattccg ctttatgaac 2460661 acttaacgcc tgttctttga ttaagtcagc aatccgtcca ggtgtaccga caacaagatg 2460721 cggctgtatt ttcaatttat caattgattt ttgtttatca gtgcctccga taaaacattt 2460781 cgagcgaatc tgacttcctt cttcaccctg cgtgatttta agcgcttcct gataaatctg 2460841 gttggcaagc tctcttgtcg gagccgtaat gactacctga acgacatcct tagcaggatc 2460901 gattttgttt aataaaggca gtaaataagc gtgagtcttt ccagtacccg tctgagactg 2460961 gccgatgacg ctttcttttt ttaacactgc aggaatcagc cttttctgga tatcagtcgg 2461021 ttcgtaaaaa ccaaggcgat gtactgcatc tataataaat ggtttcaatt cataaagttc 2461081 aaatttcgtt tctttcattt ttcccagctc cttaaagcgg cacattatgt gtccatcatc 2461141 acattatacc cgattttgct taaaaacacc acgtttgcaa ggcgtttgtt ttattcagtt 2461201 atgtaaagca aataccgcag cccatgcata ttctaatagc agagagagct gaaaggaggt 2461261 acaagtatgt tttcaccgca gcagccaatg agaaattacc cacagcccgg accgccccgc 2461321 cccatgccaa atcagcgaat gatgggcaga agaccgccta atatgcgagg accttcattt 2461381 ggagcacagc agcaaggttt tcagcaagcc ggacaatttc ttcctcaggc aaatgccgga 2461441 gcgagaaatg gtgcaggtgc aggcggaggc ttaaaaggaa tgctgtcaag gttcctcccc 2461501 ggcggaggag gcgctggcag cgccggggtt cccggaattc caggagcagg tgcagcagcg 2461561 agcggaggtg ctggcctgca aggcattcaa aatattgcca atcctgcatc attatccagt 2461621 atgcttggaa atgtgcaaaa agtactcggc atggcgcagc aagtcacccc tatgatccag 2461681 cagtacggcc cattagtccg caatctgcca gcaatgatga agctgtacag ccaattaagt 2461741 aaaagtgatg atactgagac agaggccaat gaggaaagtg aaaaacaatc cgtttcagaa 2461801 gaatcatcag aaaaagaaaa agagactgaa acaaaaacct cagatgggaa caaaaaatca 2461861 aaaccaaaaa gttcttctct cccaaagaaa tctaaaacaa ctgacaataa agaacaagaa 2461921 ttaaaaacat ctgccccgaa gaaaaaggaa gctgcctctc ctgctccgaa aagaacatca 2461981 ggcagttcaa aaccgagatt atatatttaa cattctttga tatcttaagt gagattggct 2462041 ataatgagat cagaagaatg caagaataga gccgtttgat tacggctttt tatattgcct 2462101 ttactcactt cagtattgga ggacaaccga aaatggacgt aattaaaatt tcaccgcgcg 2462161 gctattgcta tggtgttgtt gatgctatgg tcattgccaa aaatgcgtcg ctagataaaa 2462221 gcttgccaag acccatctat atactcggga tgattgttca taataaacac gtcactgatg 2462281 cgtttgaaga ggaagggatt tttacattgg acggctctaa ccgtctggac atcttaaagc 2462341 aggttgacaa aggaactgtc attttcactg cgcacggtgt ttctcccgaa gtcagaagaa 2462401 tcgcagaaga aaaagggtta gtcgcaattg atgctacatg tccggatgtg acaaaaactc 2462461 ataatctaat cttagagatg aaagaaaaag gatatcacgt gatctatatc ggcaaaaaag 2462521 ggcatccaga gcctgaggga gccgttggcg tagcgccgga gatcgttcac ttagttgaaa 2462581 cagaagaaga tgtaaagaac cttgatatcc aatctgagaa gttaatcgtg acgaatcaaa 2462641 caacaatgtc tcaatgggat gttcacgaca ttatggagct tgtcaaagaa aaatatcctc 2462701 atgtcgaata tcaccaagag atttgcctcg ctactcaagt gcggcaggaa gctgtatcag 2462761 agcaggcaaa aaaagcggac ttaacaatcg ttgtcggaga cccgaaaagc aacaattcaa 2462821 ataggcttgc tcaagtgtca gaggaaatag ccgggacaaa agcataccgg atcggcgact 2462881 taagcgaatt gaagctcgaa tggctgaaag gcgttaatac cgttgcagtt acagcgggag 2462941 cttcaacacc gacgccgatc acaaaagaag tcattcgctt tttagagcag tttgatcacg 2463001 aagatccatc aacttggaca actgaacata atataccgct caaaaaaata cttccaaaag 2463061 taaaagcaaa aaactgaggc tgtaaaagcc tcagtttttt tatagaaatg taaatggatt 2463121 tgtatctgtt tcagaaacaa agatattcac gccaaacttt ttatcattac acattgatgt 2463181 aagttttctc gtgacgcctt ctttcatgat tttttccgcg taatggcccg gatcaaccac 2463241 atttaggcca agcatcatcg catcatgggc cacatggaag tataaatctc ctgtgacgta 2463301 aacatcggct ccctttcgtt ttgcatgatg aatatacttg tttccatctc cgccaagaac 2463361 agctactttt ttcaccatgc tgtcagcatc cccaaccatt ctgacaccat tgacgtcaag 2463421 cttgtctttc acaaataaag cgaattcctt gagcgtcatc tcatttttaa gggttccgac 2463481 acggccgagc cctttttcgg cgggagtctg ttcgacagga tagatatcgt aagcgacttc 2463541 ttcatatgga tggcttttta tcattgcatt gataacagcc ttttcgacgc ttttaggaaa 2463601 tacagtctca agccttactt catgaacaag ctcaagctct cccacttcac cgataaaagg 2463661 cttagctccg tccaatggct taaagctgcc gattccttca gatgaaaacg cgcaatggct 2463721 gtattcaccg atatggccgg cccccgcatt tccgagcgcg gctctgacct gctcttcata 2463781 ttccttcggc acgtaaactg ccagcttttt cagaggatcc gtataagtag gtgccagcac 2463841 ttccgtctca ctcagctcta atgcttcagc aagcaaatca ttcacaccgc cgtccgcaac 2463901 gtctaaattt gtatgagctg cataaacagc aatatcatgc ttcaaacact tttcaattaa 2463961 ccttccggca ggctgatctg ttgaaatatg ctttagcgac cggaaaattg gtggatggtg 2464021 tgcaataatc aagtcaacct ctttttcaat cgcttcatcg ataacgctct ctaacacatc 2464081 aagtgtaacc atcacatttt taattggttt gtttaaggtg ccgatttgca ggccgatttt 2464141 atctccttca accgcatagg ctttcgggga aaattgttca aacagctgga tgatctgctg 2464201 cccatttaca cttttagcca tgatcgatta cctcctttaa cagctccatt cgatcggcga 2464261 gctcctttaa tttttgtttg ttttgctctg tatccgccgc ttggctgatc tgttcataaa 2464321 tgctttgagt gtgctgaagc tcttgtgtcc actttttcaa aaagacagca tttttttctt 2464381 ttgccaagaa agggccaacg agcatcccgg ctgataaaga aataccgtca taagccgcat 2464441 ccctgtctcc cgcttctgcc accagcacct catagcactt tccgtcctct tcaaggatta 2464501 cctcatctat cagcgcatat ctttctttat aaagccactc cctgatatga acagcatgaa 2464561 tattcggctg taaaatgagc cgttccttcc ccgttaattt gtctttgccc gcttctaaaa 2464621 tgtgagcgat caaagccccg cccattccgg caatcgtaat ggcatcagct tcaccttttt 2464681 taatcacttc cagtccgtct ccctgcctta cagaaatgtg cgagtttaag cctgattttt 2464741 caacctgccg ctttgcagac aaaaatgggc cgtctgttat ttctccggca atcgccccgc 2464801 tggctttatg attcagcacc gcataacaag gaaggtaggc gtggtcagag ccgatatcgg 2464861 ccatcaccgc tccattcggt atgtactccg ctactgtttg caatcgttta gataatttta 2464921 attcgttcac ttgtcatcac aacttttctc aatcattttt tcctttacta tcatataaaa 2464981 aatcagcccg gaatccaagc tgaagcaaat gattttgaaa ttatttcttt tgatgcgggt 2465041 ctgcacgcag cagtcaaaaa taaaaggctg tcgagaacat ctcggcggcc tgtgaatgta 2465101 taaagagaaa aatagttctt ttatttaatt tttgacaccc actctgccat atcatccagc 2465161 ttatcggccg gaacaagacc ggaaggcatt ccattaccgc ctttttcgat ctttgtttta 2465221 atttcagcga catctttctt atcccctaca ccttttaagc taggacccga aacaccttca 2465281 taattttcac cgtggcatgc gatgcagttt gccttgtaaa tttcttctgg tgaagcgttt 2465341 gcatctttct tttcagcaga tttgctttct cctccgctcg caatctcccg agagtcatca 2465401 agtcctttta ctgataaaaa gaaagttaga ccaattccta aaacagcgat cagcaaaaat 2465461 ggaataagcg ggttccattt catttccctt cccccttttt gatccttccc cctatgtaaa 2465521 cacttctaat tctaacttat ttttacaaaa agtaaatgga ttgctataca aaagtttttt 2465581 attcacactt tatacaaaat tgaatagaaa catgcctaaa tctctaatat cctttttatt 2465641 ctattgtata atgtattgta tacgcttaca atagaaaata tggaattaga ttttgaaatt 2465701 tttcaccaca atgttcattt gcaaatgaca tcatttttca gtaaaataaa ggcatattat 2465761 ccatatatct ttttaaaaaa agaagaacgg atcttcaaga cccgttccat cttattcaag 2465821 gaaatctttc aaacgtttac ttctgctagg atgtcttagt ttccgcaacg ctttggcttc 2465881 gatttgtcga atacgctctc tcgttactcc aaatactttg ccgacctctt ctaatgttct 2465941 tgtacggccg tcatcaagac cgaatcgaag acgcaataca ttttcttcac gatcagttaa 2466001 cgtatcaagc acatcttcca gctgctcttt caatagctcg tatgcggcgt ggtcagaagg 2466061 tgaagttgct tcttggtctt caatgaaatc accaaggtgc gagtcatcct cttcaccgat 2466121 cggtgtttcc agagataccg gctcttgagc aatctttaag atttcgcgta ctttttcagg 2466181 cgttaaatcc atatcttccg caatttcttc aggtgttggt tctctgccta agtcttgcag 2466241 taattgacgc tgcacacgga ttaatttatt aatggtttca accatatgaa cgggaatccg 2466301 gatcgttctc gcctgatcgg caatggcgcg tgtaatcgcc tgtctgatcc accacgtagc 2466361 atacgtactg aatttataac ctttgcgata atcaaatttt tcaacggctt tcatcaggcc 2466421 catgtttcct tcctggatca gatcaaggaa cagcataccg cgtccgacat accgttttgc 2466481 gatactgaca acaagccgca ggttcgcttc agccaatctg cgtttagatt cttcgtcacc 2466541 ttcttcaatc ttttgagcgt aggcgatttc ttcttttgca gaaagaaggt taacccgacc 2466601 gatttccttt aaatacatac gaactgggtc attgatttta acgccaggcg gtacacttag 2466661 gtcattaagg tcaaattctt cttcggcttt ggcaagctgc tgaatattag gatcttctgt 2466721 ttcttcattc tcactaatta attcaacacc ttgttcacct aaaaattcat aatactcatc 2466781 catttggtct gattcaattt caaagctgga catacgctca gcaatttctt catatgtcaa 2466841 aacgccacgt tttttaccag actctgttaa ttgctctttt acttggtcga atgttaattc 2466901 tgtctcgtgg gtttgtttat cagccattat ggatccctcc ttccaaagct tgcaacgaat 2466961 tctataagcg gtatgattct tattcggtcc attcaggcgt tttctatgtg aactgccttt 2467021 aacaatgtgc gaataatgaa atgacaattc atgatgaggt taagcgatct atttgctcct 2467081 ccgcaaggaa tcattgccaa taaatgctcc tcatcagttc tccagttatt ttaaagatcg 2467141 gttcaatgta acgatttctt gagccaaaga agcagctctt aaaaaatctt tttgcctttc 2467201 tgcttcggct ctttccgcct ctttttcttt tatcattgac caatttcttt gattcaacac 2467261 tttttttaca taatctgata actcggcttc gctaagctct tgattaacct gaagcattaa 2467321 tatatcggac aagagctggc ttatatgatc atccgtcacc ctggccatca gatgctgagg 2467381 cgtcagctcg gctccctctt cataaaaagc ataaagataa gcggctaatg cccggtgctc 2467441 atcaatatta aattgaaacc ctacccggtc aatcactttt ttgatgacgc tccgatctcg 2467501 aagcatgtga gcgagtaaca gcctttctgc attttcatac gccggacgca aacgtttttg 2467561 ccttgctttt gtcgtcagat gcgctcgccg cgttttagtt tcaccgctat tgtcagcagg 2467621 tttgttttgc ttgctgaaaa cagacagctg ctcagttaaa gactcctgtg aaagcgaaaa 2467681 ctctgaagca agctgcttta catagacttc ctgctctaga gaccctgaaa gcgtgctgat 2467741 ttctttcagt acgtctttaa tgtaagctag gcggtcgcct tcatcggaca ggttctttcc 2467801 ttttcggaaa tattgcattt tgaacgccat tacggtgaca cttgcgtcaa taatgtcgtt 2467861 tttaaatttt tccccgccga attttttgat gtaatcatca gggtccaatc cgtcaggaat 2467921 cattgcaact ctgactttgc agcctttttt ttgcagaagc tccgaagctt ttaaggtggc 2467981 ttcataaccg gctttatcag agtcatagca aagaatgatt tcttcgacgt ttcttctcag 2468041 gatcttgaca tgatcatctg taagagacgt tcccatcgtg gctatgcttt cctttacatc 2468101 cgagcttacg gccgatatga catcagcaaa cccttcaaat aagactgctc tttcctgctt 2468161 tctgatatga aggcgggcct tataaaaatt gtaaagcagt ttgcttttat gaaagagcgg 2468221 ggtttcagga ctgttcatat acttaggctg ctggctgcca agagccctgc ctgagaaagc 2468281 aacaacagcc ccgtgatgat catggatcgg aaacatgaca cggtttctga agcggtcgaa 2468341 atatccgctt ccgtcttcgc gtctgatcag gagacccgct ttttccattt gcgcctcact 2468401 aaatcccctc tttacaagga atttcgtgat aaagtcccaa gaatcaagag catagccaat 2468461 ctgaaattca ttaatcagct ctttcgtaaa gcccctagaa agcagataat ccagtgcctc 2468521 ttgaccttct tttgtattta ttaacaaatg atggtaaaat ttcttcagga gctcatgtgc 2468581 ctcagccatt ttttgttctc cagaagactc tggccgggct ccggaatgga ctgttatatc 2468641 atctggaaaa tcaatttggt atttgtcagc aaggtgagaa accgactcgg caaaagaata 2468701 gccttccatc tgccttaaaa aagagaaaac attgccgccc gctccgcagc caaagcaatg 2468761 aaaaatctgt ttgtcgggcg atacggaaaa cgaaggtgtg ctttctccat gaaaaggaca 2468821 gagtccaaag tagtttcggc cttgcttctt taattgaaca taatcaccta tgacttcaac 2468881 gatatctgcc gacttttgca cctgatccac aatttcatct ggtatccgat ttcccatctt 2468941 ataacactcc gtcgtacatt attcgatgct ttagtgcaaa atcccttcat cgttcgacag 2469001 gattttttgc agcagtgtaa taaatcgttc tcgatcttct ttattcaatt ttttaggccc 2469061 tttggcatat acgccttttc ttctttgttt gccggaaaaa tgacggccct ctagggcaaa 2469121 atcaatcgtg tcttccttgt aaagacgacc tctttccgac ataacagaga catttctgtt 2469181 caacagcaga gatgctaatc cgatgtcctg cgtcacaaca atatctcccg gtttcacgtg 2469241 atttgcgata tataaatcag cagcttcttt atgaggatca acatacttcc atttttcttc 2469301 attgcttctg gaaagctgat aatgttcaaa tgaagcgaca aaaagaactt gaacttcata 2469361 ctcggatgct gtttgtaaaa tttcatcttt taccggacaa gcatcagcat cgacaaaaat 2469421 cgtcttttct tgttcattaa gaagagtaat tctccatccc tccattaaac tcctgcataa 2469481 aagcaagcaa aatcgcacat cctttattat tgtggatgta tatgaatttg tcgaaaaatt 2469541 tccgggagaa attcttgaca tcttacccat aatagtttat tcgtatcaca cgatccttaa 2469601 acctaaaatt aatcatttta tcacaatttt ttattataat acaaacttca caaagatgct 2469661 attgtttttc attattccct tttggcacag ccaaaaaccc aggatagagc gtcctgagtt 2469721 atatgttttt tgttttgaga tgatggataa tatttgctgt ttcctcaacc gctttatttg 2469781 aaacatcaac aacctggcag ccgatccgat ccacaatctt ttcgaaatac tcgagttcct 2469841 ctttgattct gttgatattt gcataaatcg ctttatcatt aagcccgagt gattttaaac 2469901 gttcttttct gatatgattc agtttatcag ggctaatctt taaaccgatg cattttttcg 2469961 gatcaacgtt aaagagttct tccggcggat caacctccgg tacaatcgga acattggcaa 2470021 ccttcaggcg tttgtgtgcg agatattgag acagcggtgt tttagacgtt cttgacacgc 2470081 cgatcaaaac gatatcagct tttaaaatcc ctcttggatc acgtccatca tcgtatttaa 2470141 ctgcaaactc gatggcctcc acttttttga aataatcttc atcaagctgg cgcacccgcc 2470201 ccggttcgta tttcgctgtt aaaccgtagg ctgtttccat tttatcaatc aacgggccga 2470261 taatatcata atataaaaca tttgcttttt ccgcttcggc tatcaaatat tctctgattt 2470321 ccggcaccac gagtgtaaaa cagataatgc cgccgtctgc ctttgcaagt gaaatcactt 2470381 cattgatagt gcctatatct tcaacataag gaattcttct tacatgagta tcatccgccg 2470441 atccgttaaa ttggctgagt gctgctttta ctaccaattc agccgtttca ccgacggaat 2470501 ccgatacaac atagatgatg cggttattca tattatcccc ccgttagttt gcaatcttat 2470561 aggatttcat tttcagataa actgacaagt attttggtca tatttgtttt tgtcactctg 2470621 ccgatcactt caaagccttt atcggtgtct ttgatgacag gcagtgcatc aatttgtttt 2470681 tctattaagt gctttgcaat gtccatcaca taatcctcgc gtctgcacac cgtaatgttc 2470741 ggcatccttg tcatgatgat gtgaacaggg accgatgtaa gctcctgctg gccaatgctc 2470801 gctctgagca agtcttttcg tgaaagcacc ccgactaaaa cagcatcgcg gtccaccaca 2470861 aacagagtac ctacatcttc taaaaacatg gtgcaaatcg catcgtacac agaaacgttt 2470921 tcgtgaatca ctacggggat agattgaaag tctttcacct gaagcttttt gagtttatcc 2470981 gccaaaagct gtgtgccggt ttttcccgta tagaaataac cgactctcgg gcgcgcctcg 2471041 aggaatcctg acatggtgag tatggctaaa tccgggcgca atgtcgccct ggttaggttc 2471101 agcttttctg caatatgctc ccctgtaatc ggcccgtttt cttttacaat ctgcaaaata 2471161 tgttcttgcc gtttatttag ttcgatcgta ctcaccacct tttcacttca tagctatgta 2471221 aagaaataac aatccatatt ataacgtaaa tatcttgtaa tcaaacaaaa aacttataaa 2471281 tggggaaaag acgattaccg atcacacagc aaccgccttt tctctcttta ttttacaata 2471341 agggcattca tattcgcaaa ggacttgatc tcatccgcca agcttaccat ttgcgctaaa 2471401 cgatttgcct ttaatgactc attatccgct ataaccattg tatgatcgaa gtaagcatcg 2471461 atcggttctt ttaaggctgc aagtgaagca agcgccgcct cataatcttt tttgctgaag 2471521 ttttcctgca gattttgctt cgctgtttgg taggcatcaa acagttttgc ttcgtattca 2471581 ttttcaaaca gatcaggctg aatgtctccg cggactcctt ttttgctgat agagatcact 2471641 cggcctaacg cttcggctgt ttccttaaag ccaggtgcac caagcttttg ctccagtact 2471701 tgtgctttat gcagcgcaga gtacggctca agctcagagc tttccagcac ggcgtcaatg 2471761 acatcatgtc tgatttgttc agcattcaag acatatttca agcgctgagt gaagaaatcc 2471821 agcagttcat tttctttatc ggtttgaacg aaagtaagca gctcttcaaa tgaaattccc 2471881 cagttgcggt caagaagaat cgcaacaata ccgcttgctt ggcggcgcag tccgtaaggg 2471941 tcctgggaac cggtcggaat tacgccgata gagaagaatg aagcgattgt gtcaagctta 2472001 tccgccattg ctacaacagc tccggtgaaa gtagaaggcg tttctccgcc cgctgatcta 2472061 ggcatataat gttcattaac tgccgcagcc acagcttcat cttcgccaag cattctcgca 2472121 tacttttcgc ccataattcc ttgaagttca gggaattcat atatcatatg cgtcacaagg 2472181 tcgaatttag aaatttcagc agcccgcttc acatgtttta atgtatcttc atcagcctga 2472241 agacgaacgg caagtttctc tgcgattgat gtgactctcc taaccttatc agcaagagaa 2472301 ccaagctctt catggaaaac gatattttca agcttcttca catttgcatc aatgtttagt 2472361 ttctgatctt ctttgtagaa gaatgaagca tcagataaac gtgcgcgcag cactttttca 2472421 ttgcctcggg ccacattttc aatcgcgtgg ctgttgccgt ttcggactgt gataaagtga 2472481 ggcagcaggt caccgttttt gtctttgaca gggaagtagc gctgatgctc tttcattgtc 2472541 gtgacaagca cttcttcagg aattgacaga aactcggatt caaatgaacc gtaaagagct 2472601 gtcgggtatt ctactaaatg attcacttca tcaagaaggt cttcgtcaac tggaatgctc 2472661 caattgtttt cagcagccat tgtttccagc tgagattgaa tcatttgctt tcggacgcta 2472721 ggatcagcaa taacatgctg tcctttgagc tgctcttcat aagctgaagg tgattcaatt 2472781 gacacttcat gtccgaggaa acggtgtccc tgtgttgtcc gtccagactc aacgtttgtg 2472841 atcgaaaatg gaatgacatc ctgtccaaat aatgcgacaa tccatttgat cggtcggata 2472901 taacgcaaat cttcatttcc ccagcgcatg tttttcggga aatgcaagct tgtaattaaa 2472961 ccgctcaatt ctggcagaag cgacttcgtt tcttggccgg cttggaattt ttgcacgaat 2473021 acatactcta tgccttttac ttctttgatg tacaggtctt ccacatttgc gccttggcct 2473081 tttgaaaagc cgattgccgc ttttgtccag ttcccgtccg catcaagggc aatttttttc 2473141 gcaggccctt ttgcttcttc ttttatatca tcctgctttt ctgcgacatc cttaacgaac 2473201 acagcaagac gtctcggtgt attgaagagt ttcacttcac cgtgagtaat atttttttct 2473261 ttaagccagc ctgtcagctt gtcgccaagc tgaaccatgc tttcattcaa aaagcgcgcc 2473321 ggcatttcct ctaatccgat ctctaaaagt aaatcctgtt tactcatgag aagaaccctc 2473381 ccctttaagc attgggaacc ctagtttttc tcgttcctca tagtaggttt ttgctacttt 2473441 tctagctaaa ttccgcactc ttgcgatata gcccgtccgc tcggtaacag agatcgcacc 2473501 tttggcatca agcaggttga aagtgtgcga gcatttcagc acatagtcat atgctggatg 2473561 aacaagtccg ttgtccattt gcttgatcgc ttctttttca tatgtgctga acaattggaa 2473621 cagcatatcg acgtctgatg tttcaaacgt ataaacagaa tgctcatatt cagccatcat 2473681 gaataaatct tttactgtaa accctgacgt ccattccaag tcaaacacgt tttctttatc 2473741 ctggatataa gacgcgagac gctcaattcc atacgtaatc tctacagaaa cgggtttaca 2473801 ctctaatccc ccgacctgct ggaaatacgt aaattgtgtt atttccattc cgtcaagcca 2473861 aacttcccag cctagacccg cgcagcctaa agacggattc tcccagttgt cttcaacaaa 2473921 gcgaatatcg tgctcaagcg gatcaattcc aagagcacgc aaggaatcca aatacagctc 2473981 ttgaatgtta tcaggtgacg gtttaataat gacctggaac tgatgatgct gatacagtct 2474041 gttcgggttc tccccgtagc ggccgtctgc cggacgtctg gaaggctcta cataagccac 2474101 tttccacggc tcaggaccga tactgcgcaa aaatgtatac gggctcatcg tgccggctcc 2474161 tttttctaca tcgtaagcct gcataagcac acagccctga ctggaccaat gcttttgcaa 2474221 ggttagaatc atgtcttgaa tattcatttc aagcacctcc acttttcttt cataagttga 2474281 ctgcggcagc aaccaaaaaa ctcccgtctc tatgcttgcc agccgcaaac atagggacga 2474341 gagttctccc gcggttccac cctagttgct gagaacaaaa tcccagcctc ttttttaaaa 2474401 ttgctcaaga atgcctttcg ttgcgtgctc atccttagct tacaccgccc taaggtcgct 2474461 ttcatgaggt aaacgcaagt acttctttct ctcactgcaa catattttat aataaatgat 2474521 catataaaaa gatggaccaa atgtcaactt ttgttttcac ccataagatg tttcatgctt 2474581 tccatttgat ctaaaaagcg ctttgatttt aaatacaatc ccgaatattc ttcgtaatat 2474641 aaatcaatca cttgctttaa ttcagctttt gtttcctctt ttaaggacac attgccgagt 2474701 ctcgacagat caaaatagta aaagagcctt aacagccttg ccgtttgcgg tttaatcggt 2474761 atcctgtaag gatctttttc aaaacagcgg tggcatataa aaccattatc acgaacagag 2474821 aaatgaaagg ttccgtcttg gcttttacaa tgtacacaat gattcagctc aggatacagg 2474881 cccatgacac cgagcatctt catttgaaca atgaaggtga taacatccgg atctgttcct 2474941 tcattcaact gttttaatga ttctaatatg aattcaaata aataaggatt tggctttttt 2475001 tcttctgtgc ctctgtcgac taactcagca acataggcag catatgctgt taaaaacaag 2475061 tcttccctga tgcctctcat gctgaggatc atttccccct gctgaagcgt tccgaggccc 2475121 gatgtttttt gcattaagaa agaaccatac aaaaagggct ggctgactgc tgataaacgg 2475181 ctgttcggtt ttttggcgcc tcgtgccata acacctattt ttccgtgttc tcttgtcagt 2475241 aatgttacga ttttattcgt ctctccgtaa tcatttgtgc gaagaacgat cccttcacat 2475301 tttgtcagca tttccgcacc ttcctcaagc aggagcggcc aagaggttta taaaattgga 2475361 taatcaaatc gggctagctc atcttctagt tcttcgggtc tttccatgtt ctctttttcc 2475421 agttctttaa aaagaagata cgtatcaaca tttcctgttt gagaaaatac gttccaggta 2475481 aaattcaaca caagaaaccc acctttctgt agttaaacta gcttacctaa actccaaatt 2475541 cttaccttta tcttgaccag atgtcctcca tttcatgtta aacaaaattt gctaatgtat 2475601 ccctgttcct gtgagataat gacacacacg ggaagagatt aatattcgtc ctctttaaag 2475661 ccaaaatcgc gaagctggga cattttatta cgccagtctt tctgcacttt cacccacaat 2475721 tcaaggtaga cacgggagcc caacagtgct tcaatatccg ctctcgctct ttttccaacc 2475781 tcttttagaa ggcttccttt tttaccgatc acgatgcctt tctgggaatc ccgctcgacc 2475841 acaatcgttg ccgctacgtg cacagaaccg ttgtcctgcc ctttgatgga ttcgatggcc 2475901 accgcaatgc tgtgcgggat ttcttctctc gtcaaatgca gcaccttttc cctgattaat 2475961 tcagaaatga taaatcgttc agggtggtca gttacctggt cactcggata gaattgcggc 2476021 ccttccggca aatacgcttc gatctgcgcg agcaaggttt cgatgttatt tccttctaaa 2476081 gcagaaatcg gaacaatttc cttaaaagga taacgtttgc ggtattcgtc aattagcaga 2476141 agcaattggt cgggatgaat tttatcaatt ttgtttacga ttaagaatac aggcgtagac 2476201 atcgtctgca atttctcaat gatgaattcg tcgcccttcc cgtagccttc ctcagcattg 2476261 atcataaaca agatcaaatc gacttctttt aatgtatttt gcgccacttt catcataaag 2476321 tccccaagtt tatgcttagg tttatgaatc cctggtgtgt caataaaaat ggtttgtgat 2476381 gtgcctgtcg tcagtactcc ttgcaccttg tttctcgtcg tttggggctt atcgctcatg 2476441 atcgcgattt tttgtccaat gactctgttc aaaaatgtag attttcctac gtttggtctt 2476501 ccaataatgg atacaaatcc tgatttaaag ctttcgttcg tcatgtaaat cctccgatga 2476561 aaatgcgcct ggcaataatt cttccacagt catttctttt atttgtcctt gtaaattagt 2476621 cagtacgaca ataacgtctt ttgtgcaaag ctcagaaatc acctgtcggc aggctccgca 2476681 cggagatact ggtccagggg tgtcagccgc aacggccagc atctgaaact ctgtatcccc 2476741 ttcagaaaca gctttaaata aagcggtacg ctcggcgcaa ttgcacatgc tgtatgccgc 2476801 gttctcaata ttgcagcctc tgtacacttt tccatccttg gtaagaagag cggctcctac 2476861 ttggaatttg gaatacggcg catatgccat atcacgcgct tttaaagctt ctgttattaa 2476921 ttcttgtctg ttcatgtgta cattcctctc ttacctataa tggtaccgct atcactttat 2476981 attttacata atcgcgcgct ttttttcacg cccatttcta aaaatgtaaa ataaatgtaa 2477041 gaattttcag ccattacagc tttggcaaaa aaataagtaa accaatgata cacgaaatca 2477101 cggcaaaaac gcaaacagcc ccggcggcag cgtccttggc cgctttagca agagggtgat 2477161 gtttgtcagt tattaaatca accgtatgtt caatggctgt atttaaaagt tcaagcgaaa 2477221 acataccacc tatcaaaagg aatataatca tccactcaat aatgctgagc tctacaagga 2477281 agccgcaaat gagaacagcg caggcggctg cggcatgaaa ttggaaattc cgctccgtcc 2477341 gcgctgtttc ccatatgccc cggcctgcat gcacgaagct tttgaagaat cgattcagct 2477401 catttctatg atcttttgag tccataagcg tccagcaatt ccttttgctt agtaaacatc 2477461 tcctcttctt cctctttcgt catatggtca tatcctaaaa ggtgcagaaa tccgtgtaca 2477521 gctagaaatc cgagctctct tttaaaagaa tgattatact cctctgcctg ctctcttgtg 2477581 cgatcggcac tgatgataat atcacctaaa accggaggca tttcggcgcc cacgatttcg 2477641 atctcgcctt ctccctcttc ttcaagagca aatgagatga catctgtcgg agcatccttt 2477701 ccccggtatt ctttgttaat ctgatgtatg tcatcattgg aaacaatcgt gacagaaact 2477761 tcagcctgat cctgaacgcc ttcacgctca gcggcaaatt gaagcagatt ttctacttct 2477821 ttgagcatct cttctgagac gcttcccgtt tcatcaacga tatcaatcag taaactcatc 2477881 tatttcacct tcttagtagc ctccggatat tcaatccggg agtggaaaat tccttttaat 2477941 gttgcacaga gcgtttttgc gattgtatcc agctctttaa atgtcaaatc gcattcactg 2478001 aactgtccgt cctgaagctt atcggatata ataccccgga caagcttttc aattcgttca 2478061 ggatttggat tgtgcatgga tctgacggcc gcttcaacac tgtcggccac tgatataatt 2478121 gcggcttcct ttgactgcgg cttcggtccc ggataacgga actcttcctc tgtaatctgg 2478181 tcgccttttt ccttcgcttt atagtaaaaa aactttaaaa gcgaggttcc atgatgctgc 2478241 tcagcaatat cgacaagctc tttcggaaat ttatagcttc tcagcatatt cgcaccgtct 2478301 gtcgtatgcg agataataat atttttgctc aactgaggtg acagcttgtc atgcggattg 2478361 tcaatattca tttggttttc aataaaatat tgcgggcgct ttgtttttcc gagatcgtga 2478421 taatatgcgc cgactcttgc aagcaaacca ttagccccaa ccgcttcaca ggctgcctct 2478481 gataaattgg caaccattac actgtgatga tatgtacctg gtgtttccgt cagtattttg 2478541 cgcaatagcg gatggttagg attagacagc tcgagcagcc tcatggtgga taaaatgcca 2478601 aagcccgtct caaaaaacgg catcagaccg atgatcaata cagatgaagc aaaccccgac 2478661 acaaccccca tgagcattaa cgtgccgatt tcaagacccg acagcgcagt gttctggatc 2478721 aataataagg atagaacgac aaccatatta ataaacgcca cgaaaagtcc ggtctgcaaa 2478781 atctttgatc ttgcattgtg ttttcctaaa aataatacac ctgaaatgcc gctgatcaaa 2478841 taataaatcc ctatgacata attgaatgtt cctgtcacac cctgattaaa catcatactt 2478901 ccgcaaatcg caagaatgat acttcccaaa atggcaatgc gttcattcat cagcagtttg 2478961 attaagatgg cgccggccgc aatggggacc agatagccga tattattata ctccatcttc 2479021 tgaaacaaac tgacaacctc catgatcaca agcaaaagtg ttgtgattat ggagaataac 2479081 agaatggatt ggtttttaaa cttcagattt tgtttctgtt tttcaaaata atatacaagt 2479141 gttgcaatga aaagtccgat cataatcaat agcccgctga tcggtttaaa gagatttgag 2479201 ttatttaata acccggtcag ctcaagtttc ctgtacactt cccgatcaat gaggtcattt 2479261 tcttccacga gcacttgccc ctgtttgatt tgaacctgct ggacattatc tgaggcttcc 2479321 tgccgttttg cctctgttgc tttcggatcg aagacgtaat tcggaataat agcaaaacgc 2479381 ccgatttctg tcgcggctcc caagtattta gacggaatag aattgctctt tagctctttt 2479441 tctaccttat cctttgcatc agatagttta tccgaaggga tttcactgct catgaccgta 2479501 tttaccgcgg taatgaccgt atctctgaca aaagaaaagt cttcactgtc tgctttcagc 2479561 aatgtcttga tggaatcctc cgatatagaa tcattcacat ctgatgtcaa tttgtccttt 2479621 acagatttga ccattgattt ttccgatggt gatttactgc cttcttccga tgattttttc 2479681 acttcactaa tactgtcgaa tattgatgac acaaggtcaa tccgattgtc tgtatattct 2479741 ttttttaatg tatattgatc ttcaaccgcg tcctcagcgg cttgcttttt ttcctctgtg 2479801 gctttttgat cttctacggt tgccggagcg taaatggtct tgtcgctgac tgaaaacagg 2479861 tctaaatcaa gtgtttccgg cttaacatgt acaaagagca aagcaaacat aatggcagcc 2479921 agcagaagat acagcagtac atgcatggag cgggcatttt taaaactgct ccattttttt 2479981 gagctgcttt tggtcttagc cttctttttc aacacaagaa cctcctcttg aaacatcaag 2480041 cccataagca atcataaaaa tgacccgata acgcgcgatc gggtcattca gcattaattt 2480101 tgcttatcgt atgcttcaat aattttcgca acaagcggat gtctgaccac gtctgtctgg 2480161 tctagctcaa tcatagaaat gccgtctatt cctttcagca tctccttcgc tactgcaagt 2480221 cccgatttga cgcctttcgg cagatcaatt tggctaacgt cacctgtaat gatcatttta 2480281 gagccaaaac ccagtctcgt caaaaacatt ttcatttgag caggcgtggt attctgtgct 2480341 tcatcaagta taacataagc atcatcgagc gtccgtcccc tcatatatgc gagcggagca 2480401 atttcaatga tgcctctttc catcagacgt tctgtatgat ctgccccaag cacatcatgg 2480461 agagcgtcat acagcgggcg caaataagga tctacttttt cttttaggtc acctgggaga 2480521 aaaccaaggc tttcaccggc ttccacggca ggtcttgtta aaatgatttt tttgatatgt 2480581 ccgtttttta aagcatggac tgcttttacg acagccaggt acgttttccc ggttcccgcc 2480641 ggaccaatgc cgaatacaag gtcattccgc ttcatagcgg ccacgtattc ccgctgtccc 2480701 attgttttta cacggattga tttgcctttt gcgttttttg taatttcttc ttcatacatg 2480761 ctttcaaagt attcaagttc attcttcttt gccattttga tggcgtaaat cacatcacgt 2480821 tcagagatct ctatcccctt gcgaattaaa gcgaggagcg atcccagcag cctgtctgca 2480881 atctgaaacg attcatcatc gcctgaaaca taaatcgtct cgccgcgcgt aatgatattt 2480941 aaattcagat ctttctccat caatttcaaa aaagaatctt ggttcccgaa gagtgaaagc 2481001 gcctcgtccg ggtttttcag tttttgattc atcgcaagta aatgttctgt cattcttcag 2481061 tctccctgac aataggtgtg gtttgaacga tatcttctat aacttggtag agaataatca 2481121 actttacttt accattctca acagtctggt gcaaaacttt ttcacttttc acctcgccgt 2481181 tttcgcctat tttatcctct acatcctgtt tacccaattt aatgccttct tgaactgctt 2481241 cttcttttgt atattttcgc aaagcctctt cactttctct cgtttgctct ttgacatagg 2481301 atacagggag cttaaatccg agaaaatgaa gcgaatgctt ttcttgttct gtttttggat 2481361 gcttcaattc ctctttttta aacgtcatcc cccagatcgg gattgccaaa gaaccaaaag 2481421 aaagcttgtg ctttgtcctt actttgcccg tatagacgtt aaataatgtt tcaagcggga 2481481 ctgtcacttc tgatctatac caggtttctc cataaatttc tgcttttgag gcgacttcct 2481541 gctgatggtc ttcgctgccg atcagtcccg aaacaagcag ctgtcccttt tcaacatgat 2481601 cgtgtatggc ggccatgggc tgtccttttt gcacaaacat tctcgtaatg gttgctttct 2481661 ttttggcgac aatattgcgc gggctaacat atttttcttt ttcgggctca tttttctcca 2481721 caactttcat atgaatggtc gtccccttca gatcaactcc gacccaagtg atattgtcta 2481781 ttccattggt taatgatttc tgtatttttt cgggcgacat cattaaaaac tgcagacggc 2481841 cctttttgac gccgatttca ttaagatgct gcctcatttg atgttctgtt tcaggcttag 2481901 cgcctgtcac atcaattttc cacaccatat tggacagcaa aaacaaaaga atgaaaaaaa 2481961 tcgcaaaacc gatcgtaaac cctatattca gctttgattt cagcaacagg aagggaaatc 2482021 ccttccgatt gataaatcgg gctttacatt taaatttact tcttacccgc cgaaaggcat 2482081 gtacatcctg aagctgtata tataacgata cggcttcttt cttttttttg acatgaaaga 2482141 ccggaatccc ctgtcttgtg cattcattaa ggagccgctc aatccctctt cccgtcaatt 2482201 caagctggac cttacccgaa aaaaaagaca gccatttatt tttcacaaca tttccccctc 2482261 ggctttatga ctcaacatat cgaacgacat caatcgtacc ctccaaaagt atctcttccg 2482321 gaagaatcgc cttgatgaca aaatttttac cagatatgat gcactggccc tgcttcagca 2482381 tcagccgcac ttcattctca ctgaaaagca aaaggcctct gtggttttct atgtagatat 2482441 gaagtctgcc aaccattgta atcctcggca gatccatcat aacgtccggg ggaatttcca 2482501 atgctcttgt cagccaagct ttcatacgat tctttctttg ccccatacaa aaagaacccc 2482561 ctttcatctc atatgtatga tttgaaagga ggttctaaca ctttaatttt tacgggccgg 2482621 gcgcatcgta cggtgaggtt ttttcgcccg tggaggtccg aacacctctc ctagaacgat 2482681 cccctgtacg acggtgtctt tattcacctg aagcattttt tgttttgtgt atactgtttt 2482741 ttgtttggca gcagcaagat ctcgttccag ccctttcagg tttcttgctg tttccctgcg 2482801 tctttcttcc gcttcccgtc ttgcctgttc catacggtta gggataggtg caggggcatc 2482861 ttcttttgac tgcttctttt gaggagaagc agattgcacg tgttgaggtt tttttctttt 2482921 ttggctgttt tgcttttctt ctttgctctt tttgccgaaa atcgcagaaa tgattccgat 2482981 gatcgctgca ataataagcg gattggtcag taaatcttcc atcagcgttc tcccttctta 2483041 gagagattat gatttgcggt cttcatccga agggtctttc gtcagcttgc cgaatgaatc 2483101 acgcatttct gtgtcagcat cgatgttctt gatattcatg taatccatga cgccaatatt 2483161 cccttcacgc aaagcttctg ccatcgcaag cggcacttcc gcctcggctt ctactacttt 2483221 cgcgcgcatt tcttctacgc gggcacgcat ttcctgttct tgagcgacag ccatcgcacg 2483281 tcgttcttcc gcttttgcct gcgcgatgtt tttatcagcc tcggcctgat cggtttgtaa 2483341 aattgccccg atgtttttgc cgatatctac atctgcaata tcaattgaga gaatttcaaa 2483401 cgcagttcct gagtccaatc cttttccaag gactgtctga gaaatcatgt cagggttttc 2483461 aagcactttt ttatgattat cagatgaacc gattgtagaa acgattccct cacctacacg 2483521 agctacaatg gtttcttccc ctgctccccc gacgaggcgc tcgatattcg ctcttactgt 2483581 gattctcgct ttcgctttca cttcaatccc gtccattgcg acgccggcaa tgaacggtgt 2483641 ttcaatcacc ttaggattaa cgctcatttg aacagcttcc aacacgtccc ggcctgcaag 2483701 atcaatggca gcacagcgct cgaatgtgag ttcaatgtta gctcgctgag cggcgataag 2483761 cgcgttgacg actctgtcaa cattacctcc agccagatag tggctttcaa gctggtttgt 2483821 tccaacatta agtcccgctt tatgcgcttt aatcagcggg ttaacaaccc gattcggaat 2483881 gacgcggcga agcctcatcc caactagagt gaaaatgctg attttcactc cggctgccaa 2483941 agctgaaatc caaagcatta caggcacaaa tgtaaaaaat actgccaaaa caatgatcgc 2484001 tactgcgaca attgccagaa tcataagtgt tgacggatcc atataacttc tcctcgtttc 2484061 tatttaaatt tctctcacga caatgcgtga gccttctact tttatcactt ttactttttt 2484121 atctttttct gtaaacgatc cctccgatac aacgtcaagg cgttcatcat caataatcac 2484181 ggtaccggaa ggacgcagcg gtgtaaaggt tatacccact tttcccatta agtccgtgcg 2484241 cgtttgattt gaaacgtagc cgctctccgt gtttgtagaa tcatttaata tcaatttctt 2484301 aaagaatttc atacgctttc ccaacaccct tgtcagtaaa ataaaagctg taatcgaaac 2484361 agctgaggcg atcaagagag aaaccgccat gacagtgaag ctccccgcgg ctaaaaacag 2484421 gctcgcaata atcgctccca agcccagtaa tccaatgatt cctccgggaa gaaaaatctc 2484481 aagcagaatg agaatcaccc ctgctataaa gaggagaacc gtctcatacc cggcaaggcc 2484541 ggctgcaaga tgcccgtaaa agaacagcaa taacgcaatg agtccagccg ttccagggag 2484601 gccgacaccc ggggaaaaaa gctctaccgt cagacctaaa aaagcgattg tcagcagaat 2484661 agggacaatg accggattcg tcagccatct tgccgtcttt tccgcaaagc tctcctttgc 2484721 atagctgatc tgcgcctttt cgaacccaag cttctttacg agcgtggaca aattgtcagc 2484781 agtgccttct gaatagccta cctcaatcgc cttgtctgcg ttaagtgtca gcagatctcc 2484841 cttaggcgcg ccaacttcct tggcatctat atctgggtca gccattgcga gcgcatattt 2484901 tggatcgcgg ttatttttca ctgcggcatc ttccatctct gccagccaaa gtgattgagc 2484961 tttttggtca gcggcattgc cttggccatc aacaatcgcg gcggctccca tttttccgcc 2485021 aggcgccata taaatgtgat ctgcttgaag tgcaatatat gcaccagcag acaacgcgcg 2485081 tttgttgaca tatgcagtta cggggatctc gctttcggtt atcaaatcgg ccatatcaat 2485141 agcagatttg accaatcccc ccggggtatt gatatcaaga ataatatggt ctgcatgtgc 2485201 atcctttgcg tcttgtaacg aacgggacaa aaacgaggcg agaccctgtt cgacattttt 2485261 ttcaaccggg atcacataaa cagtttgttt ttctgctttt gcgttcagct gtacgcctaa 2485321 taaagaaagt aaaaatatac ccaaaagagc agcacggaat cctttgattt gaagcaaggg 2485381 cggtgtatcc ctccttcctt ttataataag tgccttctct tcatacgtaa caaatgtatc 2485441 aaaggtttca tttttttatg tataaaaaaa gacatctctc ttagaaagat gtccttttct 2485501 ttgccattta agacagttga ctgctcacaa gcttattaat taaacttccg tcagctttac 2485561 cttttacttt aggcataatt gcccccatca ctttgcccat gtccgctttt gagctcgcac 2485621 cgacctccgc gatggtttca tttacgattg tacgcagctc ttcttctgac agctgctcag 2485681 gtaaataaac ttctaaaatg tccagctctt tttgaacttt atctactaaa tctaaacgat 2485741 tagcgtttga aaattcctgg agggagtctt tacgttgctt aagttcacga gaaaggacag 2485801 tgagttcctc atcctcggtc aaactgtctt tcttaagctt aattgcttca ttttgaagtg 2485861 aagccttaac cattcgaacg acagtcagtt tgtctttctc acggtttttc atatacagct 2485921 tcatatcctg gttgagacgc tcaagaagac tcataaatcc accctctttt agaatttgcg 2485981 ttttctagca gcttcagact ttttcttgcg ctttacgcta ggtttttcat aaaattcacg 2486041 ctttcttgct tcttgcaaag tacctgtctt tgatacactg cgtttgaagc gacgaagagc 2486101 atcttcaagc gattcgtttt ttctaacgac cgtttttgac attctctttc cctccctccg 2486161 aatacaccaa tcgactacct ttaagttaca catataaaca tgtactttga cattataata 2486221 taagccatca gtcaggtcaa ctaagtgagt tcacttttcc gtcatgagtg cgactgcctg 2486281 tctatataat gaaagaaagg ggttggtgaa taggatgtta attctgatta gctttactgc 2486341 tcttatatta ttctttctcg caggcatgaa catgcttcga aagggcttaa tttcaatggc 2486401 gtactcaaaa attgaagaac gtttgctttt atttacagac catccgttaa aagcgtttct 2486461 tatcagtatt gtatttacgg ggatacttca gagcagctca gcctttatgg tcattgtcat 2486521 cggctttgta agtgcgggcg ttctttcttt taagcggacg atcccgatga ttctggggac 2486581 aaatgttggc tctactttta caactgaatt tattgctatc aaaatggata ttgtgatttg 2486641 ggttctttta ataggaggtt tattgttttt tctgactggc aggtatcctt tgaaacagct 2486701 gggaacaagc ttccttggac tgggcatcat cttcttttgc atcagcggat tcagccatct 2486761 tgccgggccg ctgacaaagc tgaaaacggg cgccgacgtt ctataccatg ttaacgattc 2486821 aaactggtcc gctttgctca tcggcatggt gttaactgcc atcattcact ccagttctgt 2486881 ctgtatcggc attttgatga gttttatgaa tgaagggatt atcggactga cacaggcgat 2486941 gagcgtcgta ctcggatcaa atatcgggac atgcattaca gctgtcatgg ctgctgtatc 2487001 cggcggatat gcggcgaaac agacagcata tgcccatgtg gtatttaacg tgctaggggt 2487061 ggctctagta ttgccttttc tgaccgcagc gaccggcttt gtagagcagt tatcacctga 2487121 tcccgcacaa aagatcgcgc atttcagcct tttatttaat gtggtgacag ctcttttatt 2487181 tcttccgctt acaaacttgt tttaccgatt gattcacctt cttatcccgg ctaaataaaa 2487241 aaatcggtac attttaatgc accgattttt taggttaaga agacaaacgc atgtgttcag 2487301 ttatttcatc ctcaaccaca cggacaaact gtccttcgtt gtaaggataa cctgctttta 2487361 ggattttgac ttttacgatt ttgccgatca tatcttccgt acctttgaaa acaaccttca 2487421 tataattgtc tgtgtaaccg acaaacatat tttcttcttc tgtttcctta aacgcttcct 2487481 cagggataat ctcaagcact tcattttcat actgagaagc gtattctttt gcaagctggt 2487541 cagaaagagc aatcaggcgg tgcacacgtt cgtttttcac gttttcatcc acttggtctt 2487601 ccattcgtgc agctggtgtt cctgtacgct tactgtaagg gaaaacatgc agctcagaga 2487661 atttatgttc tttaataaag ttataggttt ccataaattc ttcttctgtt tctccaggga 2487721 acccgacgat gacatcagaa gtaacagcta agcctggcag tgcttttttc aatttattta 2487781 aacggtctgc aaagaattcc attgtatatt tgcgtctcat ccgtttaagc actgtgtttg 2487841 atccggattg gataggaata tgcaaatgat tcactatctt atctgagcgg tctaagacct 2487901 cgatcacttc gtcagtgatt tggctggctt cgattgaaga aattctgatc cgtttcacgc 2487961 cttccacacg ggtgtctaat tcgctcaaaa gcttcgcgaa gttgtaatct ttcatatctt 2488021 cgccgtagcc gcctgtatga atacccgtaa gaacaatttc cttatatccg gcatcgacaa 2488081 gctgctgcgc ttgtttaatg acttcttcag ggtcgcggga gcggagcagg cctctcgccc 2488141 acggaatgat acagaatgtg cagaaattat tgcagccctc ctgtattttc aatgacgctc 2488201 ttgtgcggtc cgtgaaagca ggcacatcaa gctcttcata tactcttgct ttcatgatgt 2488261 tgctgacgcc attaatcggc tggcgttctt ctcggtattg gtcaatgtag ccaagcattt 2488321 tttcacggtc ctgtgttccg actacaatgt cgacaccggg gatcgccata atctcagcag 2488381 gtgaggtttg cgcgtagcag cctgtgacac agatgacacc gtcaggattt tgacgaatgg 2488441 cgcgtctgat cacttggcgg ctttttttat ctcccgtatt tgtaaccgta catgtattaa 2488501 tgacatatac atcagctgtt tgttcaaagt ctcttctttc atagcccgct tctttgaaaa 2488561 gctgccagat tgcttctgtt tcataatggt tgactttaca gccaagcgta tggaaagcaa 2488621 cagttgccat tactgatcac ctcttaataa ctctgtttga taagaaatcg cactcaacgc 2488681 gtatagcgga gcggtttctg tccttaaaat tctcggtcca aggccgcacg tcacaccgtc 2488741 ttgctctgtg agccgttcaa cctccgcttc tgttaaaccg ccttcgggac caaatacgat 2488801 caatagagat gatcctttcg gaaggctgct tacaatcgcg ctgaatgcgc ttatttcccc 2488861 ttgcttcgat gactcctcgt atgcaacgac acatttatcg aaatcctgca tcctttgaag 2488921 aagctgctga aaagaatgga catccatcac tcgcggcact tcgttacggt acgattgctc 2488981 agccgcttcc ttcgcaattt tcgtccatct ttcccgcttt ttctttgcct ttttgtcatc 2489041 cagcttgaca acagaacgcg cggcttggaa aggaataaag gcatgagctc cgagctcagt 2489101 ccccttttgg ataatccatt caagcttatc tcctttcgga aggccgctcg caatatagac 2489161 ctttatcgga agctctctgt tttcattcgt ccattctatc acaaggcagg acactttatc 2489221 tttggaaaca gattgaagtt cacattttgc ctcgaagccg tcttgagagc agcagataat 2489281 ctgatctccc tcattcattc tcatcacgtt cacaatatga tgaacttctt cgccggtaat 2489341 cgaaaaagtc ggcgcttcct ctatttgctg cttcgtgagc tcgataaaat atcgttgcat 2489401 acgctgtgac acctactaac tgttattttt tcgcaataat gctgacccaa tcttccattg 2489461 aaaggatttc tacaatggta aagccagctt gttccagtgc ttcttttact tcttgttttt 2489521 tatgaccgat gattcctgac gtaataaagt gaccgccttc ttttaacagg ctgtacgctt 2489581 gtgaagtaaa gcgaagaatg acttcagcca aaatgttggc cacaatcaca tcatgttccc 2489641 cttcaatccc gtctaacaaa ttgttttgct tcacttgagc aatatcgctg actttgttca 2489701 gcttgagatt gaggcgtgca ctttctacag ccacgggatc aagatcgtag gcatgaaccg 2489761 attcagcctc aagcattgca gccgcaatac ttaaaattcc cgaaccagtg ccgacatcaa 2489821 tcaccttatc acccttttgc acaaagcgtt caagcgcctg aatgcagagt acggttgtcg 2489881 gatgtgtccc tgtgccgaaa gccattcccg ggtccatttc aataatcagt tcatcagtat 2489941 ggaccggcgt atattcctcc cacgtcggca caattgtaaa cttttcagaa attttcacag 2490001 gatgataata ctttttccag gcagtcgccc actcttcttc atttacttca gaaatagtga 2490061 tgtggtttct gcccaaatca atattgtaaa gaaggagatt attaatcgtt tctttgatgc 2490121 cgtctacagt ttcgcccaga aaactgttaa ccggcagata tgctttgaca atgacaccct 2490181 catctgggta atcattgggg tcgagctggt agatttcccc gtacacattc tcacgttctt 2490241 taattaaatc aagcgggtcc tctatcacaa ccccacttgc accagcttca tgcaatatat 2490301 ttgagatagg ttcgaccgct tcatgtgttg tgtgaatgct taattcggac catttcaaaa 2490361 ctaccaactc ctcatccaat aattaatcgc ctttaaacgc gcgttttacc ttgtcaaaga 2490421 aactcatttc ctgttcgtca ggcaggtttc cgctgacttc ggcaaattcg cggataatgt 2490481 ctttttgttt atcagtcaga tttgtcggcg taacgacgcg gacgacgata tgctggtcac 2490541 cctgtccata gcctctgaca ttttgaacgc ctttgcctct taatctgaat ttcgttcctg 2490601 tttgtgtacc ggccggaatt ttcaatttca cttttccatg cagcgtcggc acttctacct 2490661 catctccaag agcagcctga gcaaacgtta acggcatttc acagtaaata tcatcgccgt 2490721 cacgctcgaa gaactcgtgt gcgcgtacat ggaacacgac aaataaatcc ccggcagggc 2490781 cgccgtttat tcctggttca ccctgtcccg agagacgaag ctgctgcccg tcatctacac 2490841 cggctggaat tgtcacattg attttcttgc gttttttgat ttttcctttg ccgccgcagt 2490901 ccgcacattt gtttttaatg attttgcctg taccttcaca gtggtggcag acccgtctgt 2490961 taacgacttt tccaaacggt gtattttgct ccacgtttaa ctggccggag cctccgcagt 2491021 gggagcatgt ttctggattt gttccaggtt tcgcacctga gcctttacat gtttcgcacg 2491081 tttcctcgcg gggaatttcg atggttgttt ctttaccgaa agccgcatcc tcaaacgaca 2491141 gggtcatcgt atactgtaaa tcagcaccct ggcgcggagc gtttggatct cttcgtcttg 2491201 tgcctccgcc gaatatactt gagaaaatat catcgaaacc aaaaccgccg aaatcgccgc 2491261 cgccaaaacc tccgccgccg aagccttggt tagggtcagt gtgaccaaat tgatcgtaat 2491321 gcgcacgttt ttggtcatct gacagcgttt cgtatgcttc ttttacctct ttaaattttt 2491381 catctgatcc ggcttctttg ttaatatcag gatgatattt ttttgacagc ttccgataag 2491441 cttttttaat ttcatccttt gaagcgctct tacttactcc cagcacttca tagtaatcac 2491501 gcttactcat ctcgcttcac tctcccgaat ttctcacata aattagattg tatcattttg 2491561 aattatgatt tttcaattcc ttttatcccg ggcaagaaaa aaagtcaaag ccaagagatg 2491621 cctgactttg actttctaat cattgaatca gattatgaaa tgtgttcttt tcggtcagct 2491681 ccggaagcgg ggctgacact aaaaagaact tattttttgt tttggtcgtc gtttacttct 2491741 tcgtattcag cgtcgacaac gttgtcatcc gctttgcctt cagcgtttgc tccgccttga 2491801 gcttgctgtg ctttagcagc ttcttcataa agcttcatag aaagctcttg aacgattgtt 2491861 tgaagctcat cttttttcgc tttgatctct tcaaattcgt ttttctcaat cgctgctttt 2491921 aaagcgtctt tggcatcgtt ggcttttttc acttgttctt cgtccacttt gccttcaaga 2491981 tcttttaatg ttttctcagt ttggaaaaca agctgatctg cttcgttgcg gacttcgatt 2492041 tcttcttttt tcttcgcatc agcgtcagca ttttcttccg cttcttttac catgcgttcg 2492101 atctcttcat ctgagagacc tgaagaagat ttgattgtaa tgttttgttc ttttcctgtg 2492161 cctaagtctt ttgctcttac gtttacgata ccgtttttgt caatatcgaa agaaacttcg 2492221 atttgaggca cgccgcgcgg tgctggcggg atatcagtaa gctggaagcg gccgagtgtt 2492281 ttgttgtcgg cagacattgg gcgctcacct tgaagaacat ggatatcaac agctgtttgg 2492341 ttatcagcag cagttgagaa cacttgagat ttgcttgttg ggatcgtcgt gttgcggtcg 2492401 atcagttttg taaacacacc gcccattgtt tcgataccga gagaaagcgg tgtaacgtca 2492461 agaagaacaa catcttttac gtcacctgtg ataacgccgc cctgaatcgc agcaccaagc 2492521 gctacaactt catccgggtt tacgccttta tgcgcttctt ttccagtttc ttttttgatt 2492581 gcttcttgta cggcagggat acgagttgat ccgccgacaa ggatgacttt gtcgatttcg 2492641 cttgcagaaa gtcctgcatc ttgaagcgct tgacggacag gacccattgt gcgctctact 2492701 aaatgagaag aaagctcttc gaatttagcg cgagttaatg taagttcaag gtgaagcggt 2492761 cctgcttctc cagctgtgat aaacggtaaa gaaatttgcg tagaagatac gccggaaaga 2492821 tcttttttcg ctttttcagc tgcgtctttc aaacgctgaa gcgccatttt gtcttttgac 2492881 aaatcaatgc cgttttcttt tttgaattca gacaccagat gatcgatgat aacttggtca 2492941 aaatcgtccc cacccagacg gttgtcgccg gcagttgaac gaacttcgaa tacaccgtcg 2493001 ccaagctcaa ggatggaaac gtcgaatgta ccgccgccaa ggtcgtatac taggatcgtt 2493061 tgatcttcat ctgttttatc aagtccgtat gcaagcgctg ctgcagtcgg ctcgttgatg 2493121 atacgttcta cttcaagacc tgcaatttta ccagcgtctt ttgttgcttg acgctcagca 2493181 tcgttaaagt atgcaggaac tgtgataact gcttttgata ctgtttcgcc aagatagctt 2493241 tcagcgtatg atttaaggtg ttgaaggatg atagcagaca cttcttgtgg agtgtaatcc 2493301 tttccttcaa tttcaacttt ataatcagta cccatatgac gtttgataga cataattgtg 2493361 ttagggtttg taatagattg gcgtttagcc acttccccta cttgacgttc gccgttttta 2493421 aatgcaacaa ctgatggcgt tgtgcggttt ccttcagcgt tagcaataac tttaggctcg 2493481 ccgccttcaa gcactgccac acatgagttt gttgttccta agtcgattcc gataacttta 2493541 ctcacttgaa taacctcctg ctatgtaatt attgattcac tttgaccatg gaagggcgaa 2493601 tgacgcgatc cttcagctta tagccttttt gcatttcctc aacaacaatg ttggagccgt 2493661 agttttcgtc ttcagcctgc ataacagctt ggtgcagatt aggatcaaat tcctgcccta 2493721 cagcttcgat ggcttcgacg ccttcttttt tcaaggcttc tacgagctga cggtggacca 2493781 tttccattcc ctggagcaaa cttttcgtct gttcattgtc ggcttcaacc tgaagcgctc 2493841 gttcaaaact gtcaagagcc ggcagcaaat cagtcacgat attttgagaa cggtattttt 2493901 gggacgcttc catctctaaa cggctgcgtc gtttatagtt ttcaaagtct gcttgaacac 2493961 gcaaaagttt gttttctttt tcctcaagca aaccttgcaa ttcgttaatt tggttttgaa 2494021 gaagttcgct ttcatttgtt tcttcctgct gttcatcagc ggcagcttgt tcttcaatga 2494081 tttcttgctc ttctgtttcg ttttgttcaa cggtttgttt ttcttctgac attgtgttca 2494141 cctccctcaa agtgtaagga gaaggacagg tgctgccctt cgataaaatt tgccaaaatt 2494201 cccttattca tcatacagac ttgttaatgc ttttgacaag tccgaagtca catgctgaag 2494261 caggctgaca accctggaat aattcatgcg ggtcgggccg ataatcgcaa ttgagccgat 2494321 ctgcttctgg tctacggaat aagaagccgt aatcagactg caattttcca tctcttcata 2494381 gtcgttttct tttccgattt taatcgaaat tcccgtgtgc ggggattgaa ccagctttaa 2494441 aacatcctgt tctttctcaa ttaatgaaag cagcgaccga actcgggtga tatcatggaa 2494501 ctcaggctgg ttcagcatat tgattttccc gccaaaaaac aacttttcaa cgtgatttgt 2494561 ggaatgaaag gttgaacgaa gcgcgtcgag tatattgtca tagtttttaa tgtgctgtct 2494621 taggtacatg acaacttctt taaatatgcg ctcattcagt tcatccattg gaacgccgct 2494681 taaacggtcg ttcagtatat ttaccagttt ttcaatatca gacagatcca ttttggtcgg 2494741 aaagttaatc gttttgtttt ccacatgccc cgtattggta acgagaatcg ctaccgccat 2494801 atcaggctga atcggaatga tttgaatctg tttaaggtaa ttctcactca acttcggccc 2494861 gagtacgatg gatgtgtaat tcgtcagatc ggacaaaatt tgcgctgatt tttgaactgt 2494921 cttctccagc tcgaaaattt tctctttgaa gatcgagtgg atttggtcca ggtcgctttt 2494981 cgtcaatttg acgggtgaca gcaaatggtc aacatagtac cgataccctt tttctgacgg 2495041 aacacgtcct gaggatgaat gggttttttc aataaagccc aattcctcca agtcagccat 2495101 ctcgtttctt attgttgcag agctaaatgt gatttcatct tttttcgaaa gagttcttga 2495161 tcccaccggc tgtgccgatt taataaaatc gttgattata acctgaagga tcagcagctg 2495221 acgatttgtt aacatcatca tcacctctgt tagcactctc aataagcgag tgctaattct 2495281 ataacaaaag tatcaaacca caagaaaaat gtcaattata actcacccaa aaaagcgcca 2495341 aaaacttcat tgcctaataa tttcccttga tgagtcaaat aaacggcaga ctccgaattg 2495401 tgaatcagcc ctttttcagc gaggtctttt aacacgcttg ggaaaagtcc atccagggaa 2495461 cggccgtatt tttctgcgaa tcgttttttg ctgacaccgg ctgtttttct caaacctaaa 2495521 aacatttctt cctcaatctg ttcttctgtt gtcacttcat gtgtatctct gtacggaaaa 2495581 cccttttcag ctatcaggtc aatgtaatgc ttaacaggtc cgacgttcac tgttcgtgtg 2495641 ccgccaatat atccgtgagc gccagctccg aaaccgaaat attgttcgtt gctccaatac 2495701 gttagattgt gcttagattc catgcctgcc ttagcaaagt tgctgatttc atattgatga 2495761 atgccgtgag cttccatctt gctcatcact atttcataca tttcagcttc ctgctcctgc 2495821 ggcggaagat gaagccgccc tttttgcatc aaattataaa ataccgtttt cggttctaca 2495881 ataagggagt aaacggaata atgctcagcg tccaatgata aagcagtgtt tatggaatgt 2495941 tccagatgct tgagggtttg ccccggaagc ccgaacatga gatcaagact gatattctca 2496001 aaaccgattt cccgcgctct ttcaaaagag gtgaatacat ctttttgctt gtgcactcgg 2496061 ccgatttttt ctaacagatc gtcttcgaac gtttgcacac caaagctaag gcgatttacg 2496121 cctgcttctt ttaatatttt taatttctct gcggacaaat cgtccggatt cgcttcaacc 2496181 gcaaattccg ataagtcgct tgagggcttt agcacgcggt tgatcatatc catcagcttt 2496241 ttaagctgtt cctcagacag ggaggtcggc gtgcctcctc cgataaagat tgttttgaga 2496301 tcaggctgcc cggtttttgc tattgtattt atcatttcct gttcgagtgc gtttaaatac 2496361 tcgtcgactg gctgactttg aataaaatat ttattgaaat cgcagtagtg gcaaatatgc 2496421 tcacaaaatg ggatatggat ataagctgat ttcaacggat tcaccttctt tacagaaaga 2496481 agccgcagta caagactgcg gcggcttcta ttgttttttc ggactgtcgt ccattttcag 2496541 aactgccata aatgcttctt gcggcacttc aactgagccg acctgcttca tacggcgctt 2496601 tccttctttt tgtttttcaa gaagtttccg tttacgcgag atgtcccctc cgtaacattt 2496661 agccaatacg tttttacgca ttgcttttat ggtggagcgg gccacgattt tctggccgat 2496721 tgcggcttgt accggaactt caaactgctg gcgcggaatg agttctttca gtttttcaac 2496781 gatcactttt ccccgttcat atgcgtaatc acgatgcacg ataaaggaaa gggcatcgat 2496841 tttttcacca ttcagcataa tgtccatttt cacaagcttg gacggtttgt agccgatcag 2496901 ttcataatca aaggacgcat agcctttagt gcttgatttc agctgatcaa aaaactcata 2496961 tacgatttcc gctaatggca tatcataaat gatgctgaca cggtttgcgt ctaaatactg 2497021 catatcaatg aaattgccgc gttttccttg gcaaagctcc attacagcgc cgacatagtc 2497081 attcggcacc atcatcgtcg cttttacgta tggctcctca accctttcga tcttttgagg 2497141 atccggcatg ttggacgggt tgtcgacaac gaccttttcg ccgtctgtca tatacacgtc 2497201 atagataacg cttggcgctg tcgtaatcag gtcgatgttg aactcacgct caattcgctc 2497261 ctgaatgatc tccatgtgaa gcatgcctaa aaatccgcag cggaacccga atccaagcgc 2497321 ttgcgaagtt tccgcttcat attgaaggga ggaatcattc agctcaagct tttcaagagc 2497381 ttcccttaaa tcattatact tcgctgtatc aatcggatac aaaccacagt acaccatcgg 2497441 gtttagcttg cggtatcccg gcagcgcttc ttctgcagga ttggcagcgc tcgttattgt 2497501 atcaccgaca cgtgtgtcac caacattttt gattgaggca gtcaggaagc ctacatcacc 2497561 gaccgtcagt tcatttgtcg gagttgcttt cggcgtgaac acgcccacct ctgttacttc 2497621 gaattctttg ccggttgcca tcattttgat tttttgtccc ggctttaccg ttccttcaac 2497681 gactctgata taagccacga caccgcggta ggcgtcataa agcgagtcga agatcagcgc 2497741 tttgagcggc gcctccggat ctccggtcgg agctggcacc ttttctacga tttgttctaa 2497801 aatctcctca atcccgatac cggcttttgc tgaagcaagc acggcttctg atgcgtcaag 2497861 gccgataacg tcttctacct cttggcgcac acgttcgggc tcggcgctcg gaaggtcgat 2497921 tttattgatg accggaagga tttcaagatc gttgtcaagc gctaagtaga cattggcgag 2497981 cgtctgcgct tcaatcccct gggctgcatc cacgacaaga atcgctccct cgcaggcagc 2498041 aaggcttcgg gatacttcat acgtgaagtc gacgtgtccc ggcgtatcga ttagatgaaa 2498101 gatatattct tctccgtctt ttgctttata tttaagctga acagagttta atttaatggt 2498161 tatgccccgc tcacgttcaa gatccataga atcgagcaat tgttctttca tttctcgttg 2498221 agtgattgcc gacgtttttt ctaaaatacg atccgctaag gtcgattttc cgtggtcaat 2498281 atgggcaatg atagagaaat tccgtattct cgattgcctc tctaaacgct tttctttatc 2498341 tgtcacaatc tatcactcct actattaaac gcaaaataca ctagcttaga ttatatcaat 2498401 aggattgtaa agattcaatg taaaacaaga aagagaaaag ttccctatca tatctgggtt 2498461 gcttttctct ttcacgtact tattgattca tatcccgtat ccattcatac attgactggg 2498521 cagtattggt tacggtgtcc gaaagcgctt ttccggcttt tgaaaacata ttgaatgtct 2498581 ccaccttttc cagctctttt tgtttttcta ctaaatcttt tgccgtgact gtttctccta 2498641 ggattgaggc ttctttttca ttatcttttc cgtcggtgag cgtaaacgcc cccttcagtg 2498701 aagggtcatg atagcctttc atactcagca tcccgtggtt tgcctgctgc atgccgaaca 2498761 gaacgcctaa aaacatgatc gtgacaagca gtaagcactt tccaaagtat gcaatcaaat 2498821 caaccaccta tttcttattg ttttttcgtc tccccgctcg ctgcgttgac cttttcagca 2498881 tcccagtaca tttcgctgaa tacgtccgcg gccgcgttag ccgcacgctg cagctcttcg 2498941 agattattat ccactccgcc aaactcgagc aaaagcgctc tatcggttaa atcctgattg 2499001 taaacaccat tatcgcctgg cgagcctttg gaaaagacac ctgtgctaag tccggggtat 2499061 tttttctcca tcagtttatg aagctcactc gcaattttat agttttcttc gaagtttttg 2499121 ctttttttcc cgacgacaaa ggctaccctg gcatagcttt tccctttaat cgttgcggtt 2499181 gtgtcttttt tgcgccgaga gtctctgtgg atgtcaatga tatattgcag atttttgttt 2499241 gaagcgaggg cgtctttcac gaccggcctt gattcatcat aggacctggc atagtttaag 2499301 ccttttttat tcaattttga ctgtatatcg gttttattca ctgtggctcc gattccctgg 2499361 gattcaagcg cttgtccgaa catatctcct acaagcgtga cattggcttt agaatggcgc 2499421 gccatgtcag gatcggtctc gccttttaat agagggagat atgattccgt attgtgcgtg 2499481 tgatagataa acacgacctt tttatcacct gttgtttgtt tcggcggatc tttttgcgca 2499541 ttatctgatt gcgtttgctg tttttcaatc tctgccaaat tcgcttctct ttcttcctcc 2499601 atcaccttag acggcggcgg cgattccgca ggcatattcg tataatccgt tccttgtcca 2499661 gctaacaaaa tctcggtatc aaattgtgca aatcctggca gctcccgacc gagaaagctc 2499721 cgcggatctt cgaggttaat gctcgtcgcc agctttaaag aaagacgaga aagatgaaat 2499781 gagctgtctg tttgagagag gtcagaagcg aaataatggt tttccatctg cagcaaatgt 2499841 gcaaatacgt cacccggcaa ttcttcagca atcccataaa aagagtcaga cgacggccta 2499901 agttccggcc ggagagacgt cagcacaccg gatagaacaa aaatcacgat aaggcttacg 2499961 ataaatagaa agatggcttt taccgctttc cctccattta ccgcaacaac aatctgtctg 2500021 tttctgcgtt tatttctcat tgaatccctc cagcgcttgt ctagtaatta ctctatgaac 2500081 aagctagagg aagtagaact gtttagtgat tgtaggagcc tttgttttct tgtgacactt 2500141 tttcatgaag cgctgtgttt aatccgttcg ctaaaacatt tgccatatcg tcgataaatg 2500201 aatcgacttc cttcggtgta accattaagt tgtgccctaa aggcgaaagc acctcgtgaa 2500261 tgagctgccg tttttcatct tcttgaaggg ttccgacaat acctaggaac gattggcgct 2500321 gcttttgatc gggaagatcg tcttcagtga gcactttctt tttcccaaac gtcatgcctg 2500381 ccggaacaag cgatcttgat ggcctgttat ccttcatttc tctgccaaaa tgttttaata 2500441 tgtagtccac cgtgtcgctg gcaattgtca cggcatcaac tactgtcgga acaccgatag 2500501 caatcaccgg aacaccaagc gtgtctttgc ttaaatcttt tcgtttattc cccactccag 2500561 accccgggtg aatgcctgta tccgatattt gaatggttgt gttgaccctt tccaccgccc 2500621 gcgccgccaa cgcatcaatg gcgatgacaa aatcaggctt cgattgctca atcacacctt 2500681 taataatgtc acttgtttcg attcctgtta tccccattac acccggtgca aaagcactga 2500741 caggcctgta accctcctgt acgttttccg gctgaagctt aaacaagtgc cttgttacca 2500801 acagattttc tactgccatc ggtccaagcg catcaggtgt cacgttccag ttgccgagcc 2500861 caacgatcaa acagctcgca tcttttgaga tattaaggtt ttcaagaaaa gctgagaatt 2500921 cctccgcaaa gacagcagag accttctcct gcatttccga atcattctcc ctgattccct 2500981 gtgcttcaag cgttaaatag cgcccttctt tttttcccga aagctctgcg ccttcctttg 2501041 taacatcaac tgtgcggatt ttaatgccgc cgtgatcacg ctctttttca ataaagcctt 2501101 taatttcttt tgtcggcaca gcctgctgat tggccattgc ttccttcgtt tccactgcca 2501161 aatcggtccg tatcaaatac tgattcacat ccagctcact ctttttcata caggggcctc 2501221 cttcacatta agtacctata ttgttgccat ttgctgaata aatcatgcta aaaagagaac 2501281 cttcaatgaa aaatacttta catttatatt gcaatctaaa ggtgtgtttg atagaataca 2501341 atttgttcta ttgtgaagaa gatttaacct taagacactg tgctacaggt tgtatcttag 2501401 gaggtgaaac acatgccaaa cattaaatca gcgattaaac gtacaaaaac aaacaacgaa 2501461 cgccgcgttc ataacgcgac aatcaaatct gctatgcgta ctgcaatcaa acaagttgaa 2501521 gcttctgttg ccaacaacga agctgacaaa gcgaaaactg ctcttactga agcagctaaa 2501581 cgtattgata aagcagtgaa aacaggtctt gtacacaaaa ataccgcagc tcgatacaaa 2501641 tcaagactag cgaaaaaagt gaacggactt tctgcataat ataaaaacga tcctcaataa 2501701 tggggatcgt ttttttcatt tctttttaac agctgtaaaa ggaacagttc gagcaggagc 2501761 tgcttgtcct ttttcccggt tttcatctca tagtccatga cggcaagctg ttcaataatt 2501821 aaacggagct cctcctctga aaaaagcctt gcttgatcca tcgccagctt tacccgaaat 2501881 gggtgaactt ttagattaga agcgatttgt ttttgtccgt atccctgttc cgcgaagtac 2501941 ttcgtctgca gaatcagccg gaactgattc gaaataagcg ccataatttt gatcggttct 2502001 tcattttgtt ttagcaaatc ataaaaaatt tgcagactct ctgttcgttt tcggttgacg 2502061 attttattga tcagctcaaa aatattttgt tcaaggcttc tagcaacaag catttttaca 2502121 tcatccagcg taatttcttc acgatctcca ataaacgtgc agagcttttg aatctcctga 2502181 aaaatcgatg acagatgacc gttcacaagc agaaccaaat gctccgccgc ttccgtgccg 2502241 attgttttct gctctgtttt tgcaaggttg acagtaaagt ctgtcgtttc ctttgcattt 2502301 aattccttcg cctccatcat aaacgcgtgc ttctttaacg ctttcgtcag cttttttcgc 2502361 tcatcaagct tttcatacgg agcaagcagg acaaagactg tgtaaggcgc aggtgattgt 2502421 atatatgatt caagcgcact gacgttgtgc tcaatttttt cttttttctt ttcacctgtt 2502481 aaaaaatatg gatttttcac aatgacaaga cgccgctccc ccataaacgg aaacgtttca 2502541 gcatctgcaa tcgcttgatc cagcgggtcc tcttccagat caaaaacgga cagattgaaa 2502601 tcctttgtct cctgatcaac gaccgtctgt ctgatcctgc tgacggtttc ttgcagcaga 2502661 tatgtctctt ttccgtataa acaataaacc ggatggacct ctcctttttt caggcttttc 2502721 cacacatcaa ataccattgt tgtacgactt cctctctttc atcatcccct tctatcctaa 2502781 attgagtttg caaaatagta aagaggaagc ctgactgctg cttccccatt tatattaaac 2502841 gcctgttcgc aagcccccgg gacagcttgt aaaaaggcga taatcaccag aacagaaaac 2502901 gttaccttag cttctagatt tttcaaaaca attccattat acttaagtca gtcaggaggg 2502961 ataaagttga atgattttga aaaaaacgtt caaagcaaac gaaatgatgc tgtagattca 2503021 gctgttggtt ttgttgtgtc cttcggattt ttcgccttct tgtttgtcat ggcaacggtt 2503081 attcacctag ttggttcata acagcgactg cccgggctgc tgatttctcg gcagtctttt 2503141 ttagttcgtc tctgttatat ctgatgtatc atatggagga tagacagaaa aggttccaac 2503201 tctgtttttg tatctatatt ggatcgttcc gttttgatct gttcgcagca cgcggataga 2503261 atgtctctgt aatagttgca gaactttttg atgaggatga tggtaccgat tgtttttccc 2503321 ggctgagata atggccgttt tcggctgaag ctgttggatg aattcttcac cggtagagcc 2503381 tttgctccca tggtgcccca cctttaacac atctgctttt atattcggaa acacgttcat 2503441 cacctcttgt tccccttctt tctccagatc acccgtcaag atccagctca taccgcccgt 2503501 ctccatccac agaacgagag atgaattatt tttgcttgcc ggatcaggtg cttccggtga 2503561 cagtacatgg aactgcaaat cctttatttg caacacatcg cctcgcttca cctcttcaat 2503621 tgccactccc tcttccctgg ctgcctgcag cactttctca tctttaggtt cagaaacgaa 2503681 ccctttcgga atcacgaggc gctttacttt atgatgcttc agcagaatct ccgcctctcc 2503741 gatatgatct tggtcagcgt gcgtcagaat taaagcgtca agctgcttga ttcccttagc 2503801 agttaaaaac ggaatcagca ccttttcccc cagtgaaaac ggatgctgtt tttcgcgcca 2503861 aggctctgac gagtaagaca aagtgccgcc ggtatcaatt aagacacgac cccgctgatg 2503921 cggagcacct acaaacatgc tgtcaccctg tccaatatct atcatatcca cttctccttc 2503981 ggaactaaga cacggatata taaagagcag aaacatcacc gtgcagcaaa tgcctccggt 2504041 taccatcaac tgcgacaagg agcgtttttc aatcgccata agcaatagga tgatcgtgac 2504101 tgtgaataaa aaaagcaaaa caggtgcagg atgtgcgatc ataatcgtga acacatcaac 2504161 atctgcaatg tttgtgatta acctattgat ccagcttatc aataaatcaa accagctgaa 2504221 aaacaatctc ccaaacgaag cggaaagact taatagaaga acacctgcta cagctcccgg 2504281 caaaatacag aaggtataaa atggtaccat caacatattc atcggtacgc tgatgataga 2504341 aaactgatga aaatgatata ggagaatcgg aagcgagccc agctgagcga tgagtgatac 2504401 aattgtcagc tgccccaagg aggttttaac ctgctgaaaa atagaagagg atagaattaa 2504461 agaaaaactg acggcgaacg atagctgaaa accggcttca aagagatgat aaggattgaa 2504521 gagcagaagg acgatgtacg aaaggcaaat tgcagttgca gagcggacac gccatttgac 2504581 aagacttcca gctaagtaaa cacccgacat gagagcggcg cgtagcactg aaggagcagc 2504641 gccggtcaac atcacataga gcggcagaaa taacagcaac agaattgacg ccttttctct 2504701 agttatacca aggcggatca tgatataaaa caaacctgct gtcaaaatcc ccacgtggag 2504761 tcctgatatt gccaagagat ggacaacacc aagcttttga tacgcggtaa gcacttcatc 2504821 ctccacgtaa aatctgtcac caactgtaag tgcctgtaca atccctgtcg aatcaggagg 2504881 cagaaggctg tttgtgaatg atatgatatg ttttctcaag ctgagcacct tgtacttgaa 2504941 attttcaggt tcgctgcagt tttggataga cgtgacagag tagttccaat gaatatgctg 2505001 ccgataaaga tactcgttat aatcaaatgc acccggcaca gttgcgtgat tcggttcttc 2505061 caatgtacca gtcaactcac atgacattcc tggttctatg tataacagct gttctttttc 2505121 accagcagac tgaatgcgat acgcagcagc ccatttttcc ttatcaggtg tctcaaccat 2505181 catagacata cggtcgccgt caattttggg aatagtgtca atcactgcct tgaattgata 2505241 ggttccctgc cgataggaag agacattctg agaatctgtg actgcataca gtacaaaaaa 2505301 caatataaaa gagaagaaac aaacaataat aagaaaagcg tgcctcgttt tgattaaaat 2505361 gatgaggaga aagaggatga aaagaaaaat agcggggaaa taagcggcgg cagtaattcc 2505421 agccgttgcc gaagctgccg ccataggcaa taataagcgc gaattacgca ttcatcacac 2505481 gtagctcgtg aaaagtgtat tcgcctgttc atgtatcttt ttcaattctt cctccgctaa 2505541 accggcatca gccaatttcc ctattagacc cgctacaaat gaaagctttt ctctgttttt 2505601 cagatcaacg atcatttcat cgagttcaac ctgttcaaca gttacacccg cctgttcaaa 2505661 taattcctgc gcatacggat gtgttttgta atcctcagca taataaaccg ttttgatacc 2505721 agcttgaata atagatttgc agcattgaat gcacggataa tgcgtcacat aaatctcggc 2505781 tccatcagtc ggcaccccaa acttagagca ttgaagaatc gcattcattt cagcgtgaat 2505841 ggttcttgcg caatgatcat ctatcattaa gcatccttca tctgcacaat gtacgccgcc 2505901 cgcgattgac ccattgtagc ctcctgctat catgcgtttg tctctgacta tagtagcgcc 2505961 gacagataat ctcggacatg tgctgcgcag cgccaataaa tggctttgag ccataaagta 2506021 ttgattccat gaaattcgtt ccacgttgtt ccctccaaat gttgtgttgc ctgaccttta 2506081 gtttacctat cataatgcat gaccgtcaaa tcactttact gtaatggaag actttatttt 2506141 ctcaaatgac ttttcaccta ttcctgaaac cttagtgata tcttcaattg tttggaaacg 2506201 accgttttcc tcccggtatg caataatagc ttcagctttg gatggcccca cccctgagat 2506261 gccttgtaac tcctctaagg ttgctgtatt gatattcacc agcgctccct tccctccatc 2506321 gctttggaca gaccctccgc caccttgctg cactgctgtt tcctctccct ttttcgggat 2506381 gtacaccact gtcccgtcct gcagaatctc cgccaaattt acttgcgctt cgtctgcttg 2506441 ttcactggtc ccgcccgctt tctcaattgc ctgagatact ctgtcccctg ttcgcatttc 2506501 ataaacgcca ggatgctgaa cagcaccttt gatgtctatc acaattgttt cgtttgactc 2506561 gtcgttgttt gcttcctgct ttaccactgt attttctgtc tctgttggta cagcttgctt 2506621 caccggctct ttatttttcc ctgtggccag aaagatcata atcgctgtga aaacagccgc 2506681 agaagccgct aaaataattg ctttcttatg ctgattcaac caattcatcg tgcatgttcc 2506741 ccgctttcgt catattttat tttcataaca catatggttt agaggataat agctcaaagg 2506801 aggggaaacc attgaagata ggctttatcg gcacaggaaa tatgggtacg atccttatcg 2506861 aatcatttat tgaatcaaaa gcggccgatc cctcaaacat gacaatcaca aaccgcacaa 2506921 ttgaaaaagc gttgcacata aaaaaccgct acaacagcat aaacgttacc gaaagtctcg 2506981 aaaagctcgt ttctgaaaac gagatgattt ttatttgtgt taagccgctt gatatatatc 2507041 ctttactggc aagagcgtta ccttatttaa gaaaagatca tattctcatt tcaattacaa 2507101 gccccgttca aaccgaacag ctcgaacaat atgtgccgtg tcaagtggcg cgagtgatcc 2507161 caagtattac gaacagagcg ctggcaggtg tttctctcgt cactttcggc acaagctgcg 2507221 gcgaatctgc aaaagcgaaa atcaatgagc tgatgcagca tatctctcat ccgctgcaaa 2507281 ttgaaagtga catcacgagg gttgcatcag acatcgtaag ctgcggcccc gcttttatga 2507341 gctatctgat tcagcggttt atagatgcag ctgtttcgga aacatcagtg tctaaacagg 2507401 acgcgatttt gatgtgtaag gaaatgcttg tcggaatggg aaaactgtta gaaaccgaat 2507461 tgtataccct gcctgcatta caggaaaagg tttgcgttaa aggcggtgta acaggagaag 2507521 gcattaaagc gctggaaagc ggtgtgcagg atatgtttca ccgggtattt caaaatactc 2507581 atatgaagta cgaggaggat atttccgcag tgaaaaagca gtttcatgtg tagacgagta 2507641 tgtcatacgt tcgtctgtac tgcaaaagca taaaaaagca ttttaaaaaa ccatcgtttt 2507701 aggaaacgat ggtttttgat ttctgcgcct tgaaaaagag gcgttctgat tgtgctgatg 2507761 gctcggtatc cgtaaaatca gctgtcacgc gatggagctg aaagccgcag ttcttaagca 2507821 tttcttcgta ttcttccacc gggaacgttc tttgctcgtg tgtctcatca aaacgatcat 2507881 acgcttctcc gttccacaca aaaaacgaca tatcatgaat gacagaaagc tcgtcacttc 2507941 cggcaaagct ctgccaaata tagctgatat cttcgtcctg gtcagcaaat gtgctatccg 2508001 gaaagacttc cgcaatttta aaagatgaat gaacatcaaa cagcaggatg ccttcaggct 2508061 ttaatacccg aaaaacactt ttaaaggttt cgatcacatc attttttgtt tttaaataat 2508121 ttaatgagtc acagcatatc acaacagcgt caaattgacc gtcaaagccg gtaatctctc 2508181 tcatatcctg ctgaagaaat aaaataggct ggctactcga taccttttgc tgggcgaaag 2508241 aaagcatctc ttcgctgaga tcgatgcctg taacctcgaa gcctttttcg gcaagccgga 2508301 tggagatttc ccccgtgccg catgccagat cgagaatacg gcctttttcc gggagagatg 2508361 cttcaatcca ttttgtccat tgatcgtaag gcgcgtgtga cattagctcg tcatacacgc 2508421 ttgcaaagcc ttgataaatc attgattcat tccaaagtca agatctgcga gcggagcgtc 2508481 tccccacagc ttttcaaggt tgtagtagct tctttcatcc ttgtggaaga catggacaac 2508541 tacatcgcct agatcaacga gaacccatct tgcttcatca aagccttcca tctttttgac 2508601 ttgaatgccg ttttcatcag cttgatcctt gatttcacgg gcaatcgcct gtacctgttt 2508661 atctgaattt ccgtggcaga tcagaaaata atcagcaacc agagaaatac cttccatatc 2508721 cagtgctaaa atatcctctg cccgtttatc atcgcaagcc gcagctgcga tctttaaaat 2508781 ggacttttgg ttcattcaca aattcctcct gttcagctgc cagacacaag ccagttatac 2508841 gttaaaaatg tgtctggaaa aaccggttga ttttttttca taagaaaaac cattgtattt 2508901 ttaatggact gaatcagcgc ttgattcaaa tctgtctcag caagcttacg cacctcatcg 2508961 acaccgggaa atgcccggtt tggctcaatg taatcggcaa cgtaaatgac tttttctaaa 2509021 agtgtcatgc cggggcggcc tgaggtatga tacctaatgg cgtcaagaat gtcttcatct 2509081 tgaacccctg cctctctttg gaccaaataa gcgccgaccg gagcgtgcca gagctccgga 2509141 ttatgatcca ataaatgcgc aggcattttt tcacgcgcaa taatttgttt catttcttct 2509201 ttcgggcgga atttggcgta atcatgaaag attgccgcta tttccgcttt tttagaatcg 2509261 gctccaaaac gctccgcaag ttcgatcgcc gtgttcatca cgccaaccgt atggatatat 2509321 cggtgttcgg tcaattgctg cttcacgcat gcaagtgcct cctcacgatt catataaacc 2509381 attctcctct acatacttct tcactttatc agggattaag tagtcagtgg gcttcttgct 2509441 tttaaaccgt tcccttatca tagttgatga tacctcaaat tccggaacgt ctgcaaagag 2509501 aagcggataa ggggtttcaa catgaaaacc ggggcgcttt actccaataa attgaatgag 2509561 gttcagcagc tcgtccagct tataccattt cggcaaatat tcaatcatat cagcgccgat 2509621 aataaagaac agctgatcat ttggataacg ctgcttcagt aaagaaacgg tatcaaaggt 2509681 atatgatggc ccttctcttt ccatttcaac aagctccagc ttaaaggacg gattagattg 2509741 aattgcaagc tttagcattt ccacgcgatg aaagctgtcg gtatagtctt cgttctgttt 2509801 atgcggcgga atttgattag gcataaacca aatttcatca agccccgcct ggtacagcac 2509861 ctcattcgcc attaagaggt gaccattatg cggagggtca aacgtgcctc cgaaaattcc 2509921 gattttcttc atttcaacca cctttaagga agctcgattt gtttattttc ctttgattcc 2509981 ttatataaca caatcgtatt gccgattgtc tgcaccaatt gagagcggct tccttttaca 2510041 agagcttccg ctacatcgtt tttatcctct tcgcaattct gaagcacgct gactttaatc 2510101 agctctctcg cttcaagcgc ctcagcaatt tgtttaatca tgttgtcgtt tactccgcct 2510161 ttacctactt gaaaaatcgg cgttaaatga tgcgcttttg aacgcaaaaa acgtttttgt 2510221 ttacctgtta acattctgtt cctcctaatt ttcctattac aatagatctc attttttcaa 2510281 tattaggctc ttgtccagtc cacaattgga aagacaatgc tgcctgttca acaaacatgc 2510341 ccacaccatc gagtgttttc aagccttttt ggcttgcttc ttttaaaagt gccgtctgta 2510401 ttggattata cacgatatca catacgacgg cactgctcgc ggcacgctgt aatgaaagcg 2510461 gcacatcgtc cacgttcgga tacatgccca cagacgttgt atggatgata acatcatact 2510521 gctcaagacg ttcttctgct tcttttatgc ttaatacttc tttattgtga aacgagggag 2510581 tagcttctgt aagccgcttt gctttttcta acgtccggtt gcaaatgtca aattttttcg 2510641 gggtatttcg gacaattgtt gtaaaaatgg ctctcgccgc tccgccagcg ccgatcatta 2510701 agaatgacag ttcagagatg ggcttgtcta ataccttcat taatgacttc acgaagcctt 2510761 ccccatcggt attgtatccg acaagcttat ctccctctct tctgaccgtg tttacggcac 2510821 cgagcacttt tgcactctca tcaatatgat ccaaataatc cataatggaa accttgtgcg 2510881 gaacagtcac attgattcct tgtacgccta gagctcttat tccttttacc gcatcctcca 2510941 gatcattctc ttctaccttg aaggcatgat aatgtccgtc aagcccgagg tctttcaatg 2511001 atgcgttatg aatatcaggt gacatagaat ggccaatagg atttccgata accccgtaca 2511061 gctttttcat acacctctcc ccttttctta aattaatgaa cgccgaacaa atacatgaac 2511121 gccttttggc gcgtatgcag ttaccttttt atcagcgtca tggacagtaa cccagcctaa 2511181 cccagagaaa acgatatctg tctttttgtc ttttatcgta aacgtatggg cgaccaattc 2511241 aggaaactca tccatttcat ctttacccgg aggtgtgagc aattcccctg catgcttttc 2511301 ataaagcgcg tctgcatttt caagttttgt tctatgaatc atcagctcat tcggcatata 2511361 gcaaataaaa ggagatcttt ccccagacac ataatcaaac cttgcaagtc cgccaaaata 2511421 cagtgtttgc tgatcattaa gctggaatgt gcgaggcttc agctcctttt taggagataa 2511481 tattttcagg tcctttttat tgacataatg cgccatttga tggttgttga taattcccgg 2511541 tgtatcataa agcgatgaac cgtcatccag cgggatttca atcgcatcaa gggttgtgcc 2511601 aggaaattgg gatgttgtaa taatatcttc ttcacctgac acttctttaa taatccggtt 2511661 aataaaggtt gactttccta catttgtaca tccgacaaca tagacgtctt ttccgttgcg 2511721 gtaatgctca atcgcgtcaa ttacttctct gattccctgg ccgcgacccg cactgaccaa 2511781 aaatacgtca accggtttta agccaagctc tttcgcttca cgcttcatcc attggatcag 2511841 acgctctctt ttcagtgact taggcaaaat atccgcttta ttgccaacta ataagatagg 2511901 gtttcccccc accaagcgct gcagcccatt aatccagctg ccgttaaaat caaaaatatc 2511961 aacaattttt acgaccagag agtccgtttc tccaataccg tgaagaatgt tcaaaaaatc 2512021 atcatcagtt aaggagacat cttgtatttc attatagttt ttcagtctga agcaacgctg 2512081 gcaaatcaca ttttctttcg taagcgatgc aggcggcgcg taccccaaac ctgttttgtc 2512141 ctcggtttgg atcgtaactc cgcacccgat acaaacaacc ttttccattt cttactcctc 2512201 ccactgaatg tgcccttttc gtttgagagc actcagtatt ctgcgttcga cctggcggtt 2512261 aaagcgcgta atgaatccgt cagaggaagc gactggcacg accaaaatcg tatggtagcc 2512321 gtttcggttt cccccgagta catcggtcag cagctggtct ccgatgacaa cgcagtcctc 2512381 ttttttcagc tccatattgc gcaccgctct attaaaggct ttacccatcg gttttcttgc 2512441 tttatagatg aatgggattc caagcggttc tgagaaaagt ttcactcttc tttcgttatt 2512501 attagagaca attgtcactt taatgccgtg ttccttcatt tcttcaaacc actcgatcaa 2512561 tcgcggcgtc gcgttcggcc tgtcccattc aacaagcgta ttatccaggt cagtaataat 2512621 tccttttaca tttcgttcct ttaatttctc aggtgtaata tgaaaaatat tttttacaaa 2512681 ctcgtcaggt aaaaaaaact tttttaacaa aacccgcacc cttccctttt tctttctttc 2512741 aaaatgattg tcgaaaaaaa tcgaacttgc gcctaaagaa aaactgagca aaaaaatttc 2512801 gacaaaaatt gggtttcttc accaggtgtg gataaattta cacacactat ccactcttat 2512861 tacatcactc tttagacaaa ttataaacac gatactcaca agttatccac tttttggtgt 2512921 ggataacaga acgattgttc ttatatgcat ttcatggtag attaaagata acttcaacct 2512981 cagatgaatg caacttatca ttgtatgcgt taaaatcatg aatgattcca acttttaagg 2513041 aggtgcctct cccattaatt gggttcctag catgagaaaa ctgtctgatg aattactaat 2513101 agaatcttat ttcaaagcca ccgaaatgaa tttaaaccgt gactttattg agttaattga 2513161 aaacgaaata aaaagaagat cgctcggaca tattatttcc gtatcttctt aataggaatt 2513221 tgtctatttt ttccgggcgt atttcctttt tttactcaga tgactgatat tatatcactt 2513281 tggctgcgcg ctttactact attttcagca aaaaacaccc ctaaaaagag gtgttttaaa 2513341 gggccggtta ttatgctaac cagtatatgc cgcccacaac aaggagaaca acaactaaaa 2513401 caacaataaa agcgtatcca tatgctctgc ctgcgccata catgtgaagc gcctccttaa 2513461 taaggtttta taacagccta tgtaggagaa ataaatcgga ctaggcggtt gtccggctca 2513521 acgctgcagg atctgcccat cttgtattcc ttcatatacg atccttgccc ctttaggtgt 2513581 catatgattt ccagaaggat ctataagacc agattggata agcgcttcat cagttgcttt 2513641 tccgccgtct gcttctataa aatgcttcca gttatctaca agagggacat ccaggcgctt 2513701 cgacacatct cttgtaatat cgttatatga gttgtgccat ttccttgctc cgccttttgg 2513761 ttcaaaagca gctgcttgat atctggaata gtaaaacaaa tgatgcttcc cattaccttc 2513821 tataattggg atacacgtca ttaagattgg cttgatcccg tgttttctgc tttcttcaat 2513881 aaaataaacc agattttctc taaaacgctg cttcgacact ctcggtttcc cctcagtcag 2513941 tatggcagcg tcattggttc cgaacataat aaacaaatac ttcggttttt gatccagcac 2514001 atctgtctga aatcggagac gggcatcctc tgtcgtctgt ccgccgattc ccgcattgag 2514061 tatatcaagg ttaccgcgct cagctgtttt taatatattg acccactgct gtgcttttgg 2514121 ataatcgcga taatcccaat tagagccacg cgtattactg tcaccaaatg ctacaacgtc 2514181 ttcgtatccc cttccctcgc atcctgctgt aacgaacagc agaaggaaaa ggatgataaa 2514241 atgtttcatc tttacacccc caaaagcctc actttaatgt tatacctctg tttctcttcg 2514301 ttcaatgaag agtttttcgc tatcactgtt ttttcctata gttaacgtgt ccccctcagt 2514361 gaatatcatt ctgctttcat tgcggcgcag ctgatgattt tttaaaattc ccttctttcc 2514421 aatctgaaaa acacacaaac caaagaaaag aaaataacct gaatccgcac tggaaacagg 2514481 ttatccgtta aatcctgcat ttactttaac ttcgatttaa gcttggcctt tgtttttggc 2514541 ccataaatcc cgtctgcagt taatccgttc atgagttgaa aacgcttgac ggcattcgct 2514601 gttttcggtc cgtaaactcc atctatgcca ttgtttttgg ctcccttatc agggtaaaag 2514661 tgaagtacag ctaaagcctt ttgcagctgg agaatgtttg tgccctttcg ataaggcgaa 2514721 gtgagcttta taaccccaga cggcagagga tatgatggtg aagtttcttt tggaggtgta 2514781 tccgaggaag aaattccgtt tagaaaagag ttccagtggt ccaagagttt ccgcggacat 2514841 tctttcccgg accacttttt gtggggaaca acacgattta acggaatatt gttttccttc 2514901 atcagctttc tgatcagcca ctgggcattt gatgttgctt tttcaaaatc gccgtcagca 2514961 ttttcacaga tttcaatccc gatcgatttg cggtttcctg tcccgtttgt accgtctccc 2515021 gcatgccagc cgttttcatc tatcgggaga tgctgataaa tgactgaatc gtcaactgta 2515081 aaatgccagc tttcggatgt gttcgggttt ttcacaaact tggcgtgcat tttcgcatca 2515141 gcgcctttgg ctgtattcgc tgtattatgc accgtaatat aagcaggcgc catcgcatag 2515201 ccaggacgat tatcatttga taccggtata aaatcctttt ttatggttac catttctatc 2515261 cctccctatt aataagaatg cagaaaacag agagatggac agcctttttt atgaggtaaa 2515321 aaagaattgt gttcttaacc tggttttcag ttgaacagct gaaatggcac cagttatact 2515381 aatttagatg acggaggttt tgactcctga catcacctaa gttgggagtg accatagaca 2515441 tgttaaaaaa agtaataggt atacttgtga ttatcgctat catttcagtt ggtttttttc 2515501 agaaagaagc ttggcttgat gcaatcaaag caggagggat gttttccgtt ttatttagta 2515561 tgctgctgat tgctgccgat gtttttttcc caatagtgcc gtttgctttg attgctgctt 2515621 taaatggcgc agtgttcggg actgcaaatg gaatttggat tacactgacc ggctcaatgc 2515681 ttggtacaat attgctgttt tttctcgcca ggtacagttt tagagattgg gccagaaaaa 2515741 aagttcaggc ctatcctgcc atacaaagct acgaggcttc cttcaacaaa aacgctttta 2515801 ccgctgtttt attaggaagg ctgatacctg tcataccttc acttgtaatg aacgtgatct 2515861 gcgggctgag ccaggttcgc tggcatgttt ttttctttgc gtctttaata gggaaaatcc 2515921 ccaatattgt tgttgtcact attgcaggtg ccaatttcac cagcaataaa ttattgtcta 2515981 tcagcattta cggtacatat attctgatca tcatgctggt catttataaa aagttccctc 2516041 atcttctgaa ggtgccaaaa aaataaggag gcttgttggc ccccttactt tttttctgtc 2516101 gcatggcctc caaattcatt tcgaagcgca gcaaccacct ttcctgtaaa cgtatcgtct 2516161 gttaaagaac ggtatctcat cattagtgac atggcgatga ccggcgttgc cgtctgcaga 2516221 tcaagcgcgg tttccaccgt ccattttcct tcacctgagg aatgcataat gcccttgatc 2516281 tgatccagtt tcgcatcctt agcgaaagct cgctcagtca gtcccataag ccaagaacga 2516341 atgacagaac catgattcca cactctggca accttctcgt agtcaaaatc aaattggctg 2516401 ttttcaagca cttcgaatcc ttcaccaatc gcggccatca ttccatactc aattccatta 2516461 tggatcattt ttaaaaaatg tccgcttccc gcttcaccag cgtatagata accattttcg 2516521 acggcagtat cacgaaaaag cggttccaca atctcccatg cttcatgatc gccccccacc 2516581 ataaaacagg ctccatgccg tgcgccttcc attccgcccg acgttccggc atcgagataa 2516641 tggatacccg cttctttcat ttgattgtag cggcgaattg attctttata atgagagttt 2516701 ccagcttcga taatcatatc gcctttactt aataaaggtg atacatcacg caaaacagca 2516761 tcgacaatgc catgcggtac cataacccat aggatgcgcg gcgggtgtaa taaagaaatg 2516821 aactctttaa gatttgttgt cccctcagcc ccgtatgctt tcagttcatc aacagccgct 2516881 tgatttacat catatccaac cacttgatga ttgcggtcaa tgaattgctt tcctatgttt 2516941 atgcccattt tccctaagcc gattaatccg attttcatat ctgttcctcc tgattgtcta 2517001 aaaagccttt actctttatg ttccctatgg attgtattgt gatacgcaga aaacaaatgg 2517061 ggcttacatc gtctgcgcat gtaaatttta tttttcatga ccgacggcgc ctgccagttc 2517121 tattactgaa tctctttata tccataatta tcgctttatc cttgatttac catcagttta 2517181 agttaaaata tgggaaggaa ttcgattttt tcagtaaaaa gaaggtgaca tgttgcagaa 2517241 tcaatctcat actcttattg gagttacgaa aaccgctgta ttctttttat acgctgcact 2517301 tgcaatcatc ggttttgcaa tcgggtattt tattccgcag attgcgaaat gggcattatc 2517361 cctcccctgg atccctcttg aaggaccact tcggctcatt acctcttttc agggatctac 2517421 agcttcattt atcactgctc ttctcggtat gtgtgcgggg atttggttcg ctcattctgt 2517481 tattgcaatg ctgctgtctg tcaaaattac agatcacaca gtggaattca tcaaaggaaa 2517541 aaaagtgcaa acaattcatt ccgatgacat cgctcttgta tttatggatc acaaacggct 2517601 tgtcctcctg ggaacagccg gatatgaatt ggtacgggaa gaaattgatg aaaaaccagt 2517661 aaacgttgag aaggccttta gacagcatca ttacgaatgg gcaacagatg gtgatccgtt 2517721 taaagatcaa tttcgccgat ggattcctga tgcaccagac ctatcgcaag gcgcccatgc 2517781 cttattaaaa gctcgtcaca aagcactgca ggacgaagaa aaagacgata ttgaagaatt 2517841 ccgtctcgaa ctggcacagc tgggcatcgt tgtacgggac gaaggcacac gccaatattg 2517901 gcgaaaagca gaaacctatc ccccgaaaat tcagctcggc gaaggattgt aacaacagag 2517961 gctcaagaaa gagcctcttc tttactactg cacaataaac agcactctgg taccgtcagg 2518021 atagctgctc atttgattcc ctacccacga gccggcgccg cgattatcag aaggcgtcac 2518081 atatcggaca tcagcccctg caccgccttc ctcgcagacc gccatcggcc actcatcccg 2518141 gtcatagccc ggcttggtcg ggattccctt taaagattcc tcccgccttt tgtctgctcc 2518201 atctctgtca atggtacaaa tatctggatg tccctctgca atcgcatccc taatatgact 2518261 gccggtttcc ggataacgag acagcggaaa atataacact ttgtcatacg aagatgcgcc 2518321 ttggatctgt tgcggaacca ttaaacaaag aagaactgct gcagcaagaa acaggcctgc 2518381 catccatttt ttcatcccca tccccccata cctttgttca tttcaatgta tgggcgcttg 2518441 atgaagaata tttttaacat ttgaagttag tatgctgctt accaaagccg gactcccccg 2518501 cgagaaattt cccggtacag acacagacag cctcccggtc acatacattt acatataggc 2518561 ttttgcctac atacttttgt ggaggtgacg atggtgacag gtgttttcgc agcgctcggc 2518621 tttgttgtta aagagcttgt ctttttagta tcttacgtga aaaacaatgc ctttccacaa 2518681 ccgctctcaa gcagcgaaga aaaaaaatac ttagagctca tggctaaagg ggatgaacat 2518741 gccagaaaca tgctgattga gcataatctt cgcttggtcg cccatattgt gaaaaagttc 2518801 gaaaatacag gtgaggatgc agaggactta atctccatcg gaacgatcgg gcttattaaa 2518861 ggaattgaaa gctattccgc tggaaaaggg acaaagctgg cgacgtatgc agcgaggtgt 2518921 attgaaaatg agattgtaat tacaaaaggg gggtgcatac acccctcttt aatacgtttc 2518981 aatatatatg gtgtcagaat ccacaatggt aacttctttc acgataaagt taacaattgt 2519041 ttttttatct tcaagagtta agttatctgc accgattgat tgaaaatagt cgatggctct 2519101 ttttagagca ttttcacttg agctcgtatc atctaggact ttcatttttg actggatttc 2519161 gttacacttt tcagtaagct gattttgctt tttttgcagt tcaataattt gtgctttgat 2519221 ttcatctatg tctaaatcat cgtcatcgct taggctgatt agcgttaaaa gacgcttgcg 2519281 gccttttttt gttttctcta tctctttttc aataagttct aattcatcag acaggtgatt 2519341 tgattgttca gcctctttaa aagaaacata cttttgagga tttgtgatga atttaaaaat 2519401 ttcaccccat acatgccggt tcaatttatt ctcagacatt tcttttccgc agccgcggtc 2519461 ctttgcgcca gaataatttt tccggcaagt atatacatag tagtctttac catgtgattt 2519521 tcttttcttc cctgtcatgg tatttccgca ttttccgcat ctaaccaaac ccgataacaa 2519581 gtaattgtga gggctgatac tcaagtgttt tcttttactt tgacctaaga gttcttgagc 2519641 ataatcccat tgttcagctg gaacaattgc tggaattgtc acagtgattt gttcttcttc 2519701 aggccttatt ttaattatag atttgttccc tgcctgcttt gaaacatagg aaccctctgt 2519761 atcatattta tactgtctat gttcaccctt ataggaagag ttcattaata tttgccgaac 2519821 aacctgcctg tgccatactt tggcgccttt ttttgtttta acccccatct gagttaaatg 2519881 tagagcaata ccatttactc tgccgaaaaa agggctttta tgatcggtga aatagttaaa 2519941 aatcatccga atgatttttg cttcctcttc taatatctca agagttcttt tctctttaac 2520001 aaatttatag ccatatagtt tagaatcttt aatgatcatg ccttttttca ttttttgaag 2520061 tcggccgctt gatgtccgtt ctttgatttt ggctttttca aattctgaga ttgccccgcg 2520121 cattgcgaaa aacaattgac cttctggaga attggcgtat tcaccattta caaaaatcaa 2520181 aggtatgttt cgctttcgca attcgtcatc aatgattagc tgattcatta atttccgaga 2520241 aagacggtca ggatcgtaac aaatgacttg acttataagt cccttgcttg catcctccct 2520301 caagcgattc aaagccggac gttctaaaag ctctcctgaa aatccttcat ctgcatactt 2520361 cagcacatct ttagtccctg ctttctttat acaggcctcg atttggctgt cgatgctcga 2520421 tcccttgatc gcttgttcct cggtcgatac ccttacatat attgctatca ccctgaatct 2520481 ccttcctata aagttttatt aaataatgat agcaatcgtt aatgcatttg tcagcttgcg 2520541 gtccctcgat gattatcact ttcataaaat gcatcacccc ttgggtaatg ctatgtaaca 2520601 gctgtttgtc caaatgagga gattttaaat taaactatag tgttattaaa cgtttcaatg 2520661 aatatgcaaa aaatttaaaa aaagttgttg tgacttttct acactccttt aggtcctcaa 2520721 tagaaaagat tttattttct atgcctcaac attcgcttat tatagttttc aatgatttat 2520781 tattatttga gagtacaatg gagtagtgtt tttcattgtt agatagttaa tgacatttca 2520841 ctggtgtcaa gttcgtatag ctagacatta ataaaaaaag gacacatata aatatgcatc 2520901 ctttaacaaa agagtttatt tatttccctg tttcagcaaa ttccttcaac ctattcccta 2520961 tttcatcacg aactctttgg aaaaacgccc atttttcttc ttctgtccct tgtgctcttg 2521021 ccggatcatc aaaaccccaa tgctcacgtt ttacatgtgg aggcgtcatc gggcatttat 2521081 cagcagcatc tccacaaagc gtaacaacta aatcagcatt gttcagaata tcagaatcga 2521141 ttatatctga cgtttgatta gagatatcta taccaacttc cttcatcgct ttaacagcat 2521201 tcggatttaa tccatgtgct tctatccccg cgctatacac tttccactca tcacctaaat 2521261 attgtttagc ccatccttca gccatttggc tccggcaaga gttccctgta cataaaaagt 2521321 aaatgatttt attctccata tattccacct ctacatcgag tgacttccaa agtattttcg 2521381 ttgaaaccat aaagcaacct taacaagtgc tatcatgact ggcacttcta caagcggacc 2521441 aattacggcg gcaaatgctg cacccgaatg aattccaaat acaccaacag ctacagcaat 2521501 cgctaattca aagttattgc ttcctgctgt aaaagctaaa gtagtagtta cagcatagtt 2521561 tgccccgatt ttcttcccta aaaagaagga aacaaagaac attaaaacaa agtaaatcaa 2521621 taatggaatc gcaactcgga caacatctaa cggcaagcta acaattacat caccttttaa 2521681 ggaaaacatg acgataattg taaatagcaa agcaattaac gtaattggac taatcttagg 2521741 aatgaacact ttttcatacc attctttgcc cttcactttt acaaaaatat aacgtgtcac 2521801 cattcctgca ataaaaggaa ctccaaggta aatgaatact gattttgcga cttctgccat 2521861 cgtaatattc actactgctc cttccatccc taaccattgc ggaataactg ttacaaaaat 2521921 gtaagcataa actgagaaaa aaagcatttg gaaaattgag ttgaaagcaa ctaatcctgc 2521981 cgcgtattcc gtatcacctt ttgataagtc attccaaaca ataaccatcg caatacagcg 2522041 agctaatcca atcataataa gcccaatcat atactccggt ttatctggca aaaagatgat 2522101 agccaaaata aacatgagag tcggtccgat gatccagttt tgcactaaag ataaaattaa 2522161 cactttaata tctttaaata cccgtccaat ttcttcatat cgaacctttg ctagtggtgg 2522221 atacatcatt aatactaatc caatagctaa agggatagat gtagttccta cttgtaattt 2522281 gtttaatcca ccaacaaaac tcggaaatat aaaacctaat cctatcccca atgccatcgc 2522341 aagaaaaatc cagatggtta aataacggtc taaaaaagat aaacgtttca ttactttatc 2522401 ctcacctttt ttactaacag caagagttcg ttgtaatatc acttggcggt gttacacaac 2522461 aagaggagga atcttgtttt tgaacctcgc tgttcgattt ggtatagaaa aattcccact 2522521 cgttcccatc tggatcagta atccaaaatt tatcttggac tgcataacaa caagtcgtat 2522581 ccatttcttc acgtgcaaaa aacccttctt tttcaagcct tttcttgtgt ttcaaaactt 2522641 cttccaaact atctacttgg aatccaaaat gattcacttg atttcccttc acctcatctg 2522701 cgacatttaa agtgaaattc agtccaggag tctctaatag aaactttgca tagtctgttt 2522761 ttacttttac agcctttact ccaaaaactt tttcataaaa attgatcgat ttctctaaac 2522821 tgacaacgtt aacccctaca tgaacatatt tcattttaat tccccctctt atatattaat 2522881 caaaaaaatt tgatataata cctaaaaaat ttttttagca gcaatctcct tcaccttttt 2522941 ttctaaatat acaacaaagc tcttctgata ataaaccatt tacttcctca tcatttagat 2523001 cataataact ccatgttccc tttgtctctt tcgttattaa gttggcatcc aataaaattt 2523061 ttagatgata agaaagttta gattgcgtca cctcaaaaat ctcagtcaga tcacaaacac 2523121 aggtttttcc cctttgacaa agttcataca tgatctctaa tcgtttctga tcagcaagag 2523181 ccttaaattt ttgttcatat ttccgtagca gttctgattt cgtctcatcc attcatatcg 2523241 ccttctttaa tcaatttttt ttgatgtatt tattatactc atgattttta aattaatgca 2523301 agcaaataaa tcaatttatt ttgattaatt gtaaaacccg ctaaaagctt gtgtaaccag 2523361 atagaggttt tccattttta ttatttcctc catcgctact ttgctactac agcaacggag 2523421 atcataaacg ctaatttcta atttcaagaa aaaaacatta aataattttt gtgaatatgt 2523481 agaatcgata ataattcgag ataatacgta tttagtcaga gcacacagat ttatcatcaa 2523541 ttaaaacctt atgtgaagat ataagccatt caatccatcc ttccacataa ggttttaaac 2523601 aatttaatca gaccttttct ttttgaataa gttcttcatt ttcataaaag ggcattgtga 2523661 cacttgattt tcatcatctc gcaagaagta ctgtttccac tccagattgt ctttttttcc 2523721 ataccatcct aaatgcggat ggataggtac ttcatcatat gcctcaagcc tttttcgaat 2523781 ttgcttactc atatttcgtc caaatgcagt agtatcattt agatcctcaa aaacccatct 2523841 aggctgaaac gtcaacataa aataaggaaa acttctgctt tttcttttgc tgtgagccgg 2523901 tgtagcacac agaacaaaat atggttctcc attaaaacag tattcccatt gaaagttatc 2523961 tggattttct ggtatatcat ctggccaatc agctggatct tccatactca atgaattgag 2524021 caactgccaa aacaacgatt cgtaatcctc aattttgtaa tcagtcagta attcttctgg 2524081 tgtatgaaat attacagtta atgatgcata ctttcctgtc tctcgtgaaa tagttccata 2524141 ccgagtaagc aatggcgcta attccttcgc agtctcggga ttcctaggat caccgacaaa 2524201 agcaattcgc agctggtcgc ttaaaaatgc ttgccttccc ggtatacaag gaaatttatt 2524261 ttctttatca cctatttttt cattcaaata gttaaacgaa tctaattgcc aaccaggtag 2524321 cgtttcttta attttttcaa gatcactttt agcatataac tcagtcaata aatccacctc 2524381 cgaaggcatt tatcataatg tattgcggga gcacgaagga ggtgaatgtc taattacttt 2524441 ttcatatatc caaatgaata ttaattaatt aattggttaa gttttagtgg gtaggtaagt 2524501 aattttctta tcaagaaaaa tccagaatca gttctgcgtt tagctgtaca tgcacactca 2524561 gccctcaaaa cgactaacgc tggactttct ggatgttttc aattttaaac tatcacaaga 2524621 atgaccgaaa ttccctgttt tttgatgcca agtcatggta ctcccaggag ggaatttcat 2524681 aactctctaa agcaaaaagt tattgcggtc tcaccgaaaa tttaaattgc ggtgccctat 2524741 ttcctttttc tgcgaacgaa aacttgttaa tatttacagt actagtagag ttaagggaag 2524801 ggtgaatatc ttgatatcaa tcacatcagc tgaagtggga atgaagatta atgaatggca 2524861 taggcatatt caaaaattca acgtaactga tgctgaaatg ttaaaagctg aaatagaacg 2524921 tgatatagag gttatggaag aagatcaaga cttgcttatt tattatcaac taatggcctt 2524981 tcgccataaa attatgttgg aatacacgct gccatctgat gaaaaccgaa tggaactttc 2525041 agaatattta aataaaattg agggccataa gaaaaaatta gacaatatgc gggcatatta 2525101 ttataacttc ttccgcggga tgtatgagtt tagaaacggt gaatacacaa gagccattac 2525161 atattacaaa aaagctgaac gcaaaattcc tacaatctcc gacaagattg aaaaagctga 2525221 gttttatttt aaactgtctg aagtctatta tcatatgaaa atgacacaca tttcgatgca 2525281 ttacgctgag ctttcataca acatttataa gaaacacgag ctttactctg ttcgtcgtat 2525341 tcagtgccat tttgtcattg ccggtaacta cgatgacctt gaaaatcatg aaaaagctct 2525401 cccccacctt caagaagctt taaaaggtgc cgagctgctt aaaagtaaaa atactcatat 2525461 ctatgccact gcgtttttca atctcggcaa ttgctatcac aaaatggaca acttaaataa 2525521 ggctgctcgt tacatcgaac aagccttggt tcaatacaga aaaattaact ctgacgtact 2525581 tccgcaagct tatcatgacc tagcgttgat ttattttaaa caaggcaaaa aagaacaagc 2525641 aatggattgc ttccgcaaag gaatcagaag tgctgtagat tttaaagacg aactatttat 2525701 gaacttattt gaagcattag acgttcttta tataagaaat ggcgatacac ctaaacttct 2525761 caacattttt tctcgtttag agaacggcaa aggataccct tatctggaag agctggcatt 2525821 gttaggaggc aaccttttcg attataatgg aaaaatagag gatagtatca tctgtttcaa 2525881 gaagatggta tatgctcaaa agcaaatatc gaaaggggaa tgcatgtatg aaatctaaat 2525941 tgtttatcag tttatccgcc gttttaattg gacttgcctt tttcggatct atgtataatg 2526001 gcgaaatgaa ggaagcatcc cggaatgtaa ctctcgcacc tactcatgaa ttccttgttt 2526061 aattcgataa acaacattag ttctgattcc ctttagccgt ttcataacgg ctttttctta 2526121 tttctaatac tgaaaaaatc tatcatactt aaagcttttg aggtgaacat tttggactta 2526181 tttgatgaat gcttagaagc tctagggaaa aacaaagaaa tcttatcaga agaattaacg 2526241 gcaaaatatt atgaactgct ttcaaacagt tttcccttac atcttgggga cgaatcaagt 2526301 gggaagaagt ttgttgtcat caatctatag attacgagga agagatttac gattggctag 2526361 ctaaacacca ttttaaagat aggaacatta ttattctttg gggttacgga gaacagccag 2526421 cattaaaaac cagtcttgag catgcattaa acgtaattga tgatgtaact gccgttggat 2526481 cggatacttt tatgtttagt gaatctggct acgttatcga attttttcat gatggcgatg 2526541 ttacaattgg aaagtcccct ttcattgaaa ggattaacaa ataggtaaaa tgacacagat 2526601 cgaatgattc atttccacca tttgatccac ataacagtta gtttcatcat tcttccatgg 2526661 taatattttg ttatgacgat taaatgaaag gatatgatca tgaaagtatt tgaagccaaa 2526721 accttgctca ccgaggctga aaagcgagca caggaataca aagatttaaa aagtaaaatg 2526781 gtcaaattaa agaaagcgtt caaagctgtt gcagatttag atgatagcga gttttcaggc 2526841 aaaggcgcta ataacattaa atcattttat gaagatcaag ctggcattgc tgaccaatgg 2526901 attgatttaa ttgagatgaa aatttctttc ttaacgagta ttcctggttt tttagaagat 2526961 gccaacttat cagatgccta catagaagaa acctttttag cgcatgagct tgctaacgcc 2527021 tacaccaaat caaaatccat tatgtctgaa cagaaaaaag ccatgaaaga tatattaaat 2527081 gatatcaacg atatactgcc tttggatctg ttctcgacag aaacttttaa aaatgaactt 2527141 tcgtctgccg aaaagaaacg aaaagaagcc attgagaaaa tggatgaagt tgaccaaaac 2527201 ttaacatcag aatacggact atcagaagca aatgaacaaa tgattcaagc tgattatcaa 2527261 gctttaatga atgcgacagc aaaaggcaaa agcgcctctc ctattcacta taatgcgaag 2527321 gcttatagag acagtgagat tcacaagatg actgaggatg taaagaaaca atcaacagac 2527381 tacatctctt ttaaggacca acaggcggaa caaagaagaa ttgcaaaaga acaagaagaa 2527441 ctggcgaaca gaccatggta tgaaaagtct tgggatgctg tttgtaattt tacaggagag 2527501 gtctctggat attatgatta taaaagagcc gctgatgggg ttgatcctgt taccggcgaa 2527561 aagctaactg ctggacaacg ggtcgctgcc ggtgcaatgg ctgcggcagg atacatccct 2527621 atcgtaggat gggcaggtaa attagctaaa ggtggaaaag ctgtttattc aacaagtaaa 2527681 gcattgtata gagcagacaa agctctcgat gtatataaaa cacctaagac attccatgcc 2527741 cttcaaaact ccagcaaagg actttatgga cttgcttctg caaatggttt tagtgaagct 2527801 ataacaggac gcgatatgtt cgggaataaa gtctccaaag agaggcaaga acagagcctt 2527861 agtggtgcaa tggcaatgtt ggttcctttc ggagctcgcg gaattaacaa aaagcttaat 2527921 gcaaaatcaa gttctcgagt tagcgaagca tcgactaaca ccagcaaaaa acctaaagtt 2527981 cctaaaacgt acaaaagacc aacttatttc cgtaaaggcg ttagagataa ggtttgggaa 2528041 aatgctaagg attcaaccgg atctgttaaa gacccgttaa caaaacaagt aatgaaaaaa 2528101 gatgaaccat gggatatggg tcataaacca ggttatgaat ttagaaaaca tcaacaaagt 2528161 gcgatggaaa gaaatattag tcgaaagcaa tttttagatg aacataataa tccagaccac 2528221 tatcaacccg aattaccttc ctccaatagg agtcataaag gggaagatat gacggatgat 2528281 tactttggag attaaggaga gattgtctaa tgggcgtaac acaagaaaat aaagtaattg 2528341 ctagaacagt tttaggagct tttgggggga aaccgaaggt tacgaaatat tgggatgata 2528401 acaagaatag cagcatagat attttatcgg ttagtgacca gcctcaggaa ggtatcacgt 2528461 catattcaac tctaggtttg tcggatcatt ctattaatta tgaggtgaat ggcactccgt 2528521 tgcggataga aatcgtagct gcaatggagt cagcttcaga catatatgct aatgttttat 2528581 caacttgtgc ctttaatata atcaactcaa atttcacttg tgcaccaggt gttattttta 2528641 aaaatgtgat tagtatgtat gatcaggaaa ccgacatgaa acatattatg ttcgttcccc 2528701 catttttatg ggaggaagat ttagaactac ttgaatttag taacaaaaat gttacttggc 2528761 taatggcttt acctatatcc gaaggagaat tgcaagtagc tgaaaaacac ggctcagatt 2528821 atttacaaga tcttctggaa tcaaaacaga ttgatatttt tgatataaag agagaatctg 2528881 ttgtttaatg actttaataa agaagagtca ctttataagc ccctctcaat gagaagggct 2528941 tattttattt aatttgaaat cagctgcaaa taatagaaga aaatgactga ggtaaggaga 2529001 attctatgat taatgaagaa aaacacacaa accctcaagc taataacaat atatttggaa 2529061 ggatagatac ctggtattct gttcatagga gttcgaactt gagggaaaat aaagaaagac 2529121 cagcttatta tgtggctggt ccttatcttt aattaaagaa atggttatgt aaagctttag 2529181 aaaatccaaa accttcttct ggtcccttta accagagaga aataaacttt tcgaaatcca 2529241 cttctttttc aatatctttc aaaattcttt taaattcttc agtaaagtta tgaagagaga 2529301 cctcttcgcc atttttaatc ttatcagtgt actggctcgt taactctctt aattcttgat 2529361 actgtttttc acttaaatca taggccaaaa cttgatcaaa taagccaaac cgatcataat 2529421 cagctgctaa ttgttggact aaccttagtt gaaaagcctg cttctcgact tttttttcta 2529481 ggttgtcaag cctttcttct actgttacca attcaaatca cctcaattaa aaagctaaga 2529541 aagtaaatac acttgcaata gttctagctg tagaagattt tacaccagca tcaattagat 2529601 atgaggaaac cgtgtcaata attgcgtcct ccacaacgtc acctcgttta actaactcgt 2529661 ccaaagcatc tgctacatca tcagtatgtt ttgcgaatgt ttttcctgct gatccaccta 2529721 actcatcgac tacctcacca acaattctcc caccatgtcg aagcgcactg gctgttgcct 2529781 tcattgcttc tttagcaatc cattttttaa taccatttgt gtgaaattca ccagattgtt 2529841 cagttgtatt agttggtaat tcggatagtt taacgggagt ttgataagtg acttcctgct 2529901 gtgcctgtaa tgttacctct tgagctttgg catgtccatc caacggaaga actaatgata 2529961 aagagaatgt taatgcagat gttgctaaaa gtaatttctt aaacatgaaa tcaatccctt 2530021 tcttttaaat tatttacatg taaatgataa cattatgttc agactagaaa aataatactt 2530081 tttactcaaa tattagaata attttgaact atctgtaaca aaataaacat aagtatctcc 2530141 ttgagaaaga tactcaagga gactatttat ttacttcaag agagcttcaa gtttcgcttt 2530201 cgtttttggt ccgtaaatac cgtcttgagt aagcccgtac atagactgga atcgtctaat 2530261 tgcatctgct gttttcggac catacacgcc gtcaatgccg ttgttttttg ctcctttatc 2530321 cgggtaaaag tatagtgcag ccagtgcttt ttgaatttgt gttacctttt cccctctcat 2530381 cattgggctc ttcactttaa aaataccgga tggtagcgca tatgacgttt ttttgctgct 2530441 tgtgtttgtt gttttctttt tagctacact tgctttgctt gagtttgttt ttccgcccaa 2530501 ctttttcaat tctgcttcaa ttgcagtctt aacttgaatc catcttccct ctgacaaaat 2530561 gcggtgcggg caatacttac cattccagtc ttgatgtttg cggactcgat caatacccca 2530621 tccacgttct ttaagtagct gagccacaaa cttaatagca agcttttccg ctgccttata 2530681 tcgtacccct cctgacttgc tataacaaat ttcgacacca atagacttgc gattccctgt 2530741 accgtttgtt ccatctcctg tgtgccaagc gttacgattc gttggaatac cttgaatgac 2530801 ttgtttatcg tctactgcaa agtgaaaact tgttgagcta gagttattct tcatgtaaga 2530861 aatctcattg gctgctgaag catcattcgc agtgttatga atagtgatat attcagcttt 2530921 cattggatta ggacatttca atccatactt tgatttagag actagattct ttacaacttt 2530981 aatggccata taccctctct ccttctgtca gtaagataaa aaaagccact ggcttagcca 2531041 gcagctttgt ctgcgttatt cttactctgt tctttttcgt tctcaattgt ttgtaatcga 2531101 tctgttattg atgatggtat tttaacacca atctgtgcta agttttcagt tattgacaaa 2531161 ccttcattag cgatataaaa aagaacggta ccaaaggtta agacaccgtt caaattgagt 2531221 actgtatcaa tcacgtttgc taaaatgacc gcaaagaaat tgagtagctt gcggacatag 2531281 ccaaaccatg cgcttcgact tcgcagtttt ttgaatttcc atgccttgat tactcctgtt 2531341 aaaacgtcaa ttatgctaag tactagaagt aaatcaaggt acttcacccc tccaaataaa 2531401 tatactcttg ctaaatctaa tgtttcaaaa ttgataaaca aacttgtctc ctccattcta 2531461 atcacctcct ccgaggcaaa taaaaaagga cagccggatc ttatgagacg gccgtccctc 2531521 taactgaaaa gtttccattt gttaaagctg taagctccat aacaatttct ttaaagccag 2531581 taatgctaaa agaccaagct tctgattttc cttttgtgct agtggcaaac gttccgtcat 2531641 ccactttctg ccctctaagg gctctttttg ttcccgataa ggatttaccc cagaacttca 2531701 attcacttgt ctcagccgtc ccataaacct caatgagcaa cgttttgaat gatccaacgg 2531761 tgaatgggtt accctcacct atggtttctg ttttatcgtg aaagacaata tccattgttt 2531821 ttgattgagt gtctaatgag ctaagattca agccttcagt ttgaactttt aaacgaccat 2531881 cattagttaa cccgctttta tctaactgga ctgagaacgg agcaactgct gtaataggaa 2531941 cagtatggtt aatgtttata tcctcttcac ctgcgcccaa tgactggtaa agtaagaatt 2532001 cagattgctg caggttacca tttgcgtatc tgaaacggaa atatcgttta gttaaatgaa 2532061 tccactcagt ctcgccaagc gtatttgctt taacaaccaa tgaagagatt gtggtccatg 2532121 aattcatatc gttactttct tcaatgaata aggtaccttc acgatcagaa taagcgtgac 2532181 cttttacttt tgaaattaaa acctgaccta atcgatcttg tccatattgc gtgtagactt 2532241 cagtggcttt taaaactgcg ttcgtcagca gctctgaatt accggagatt gaagctaccg 2532301 gcacaacaaa atctctgttt ccttctctgt atggcttggc tgcccccggc ttaccagttg 2532361 catctgttga aaattgaaaa ctatatgatg ccattataaa tcctccttgc tattgtagat 2532421 cattagtggt gagcatgggt ttacaacgga accacctcct ttaaggaaaa ataaaaaagc 2532481 cctaaatggc ttctcctgtg atctctttat actgttcagc tgtaatgagt tttttctcta 2532541 ttccttcctg taaatcttcg ggcgaacaat ctttgagatg aattgcctgt ttcaccattt 2532601 cagaagaagc ccagttataa tgcaaagcca gcacccaata attcatgaac cttgccctcc 2532661 ttgtagagta agcagttgca actttatttt tgaaagctcg cttcccaaag tttggtttaa 2532721 ttcttcaagc tgtttacgag ccagtttttc ctgtgacaac tctcttgcaa gtagatccac 2532781 ttgaactggt ggttcatatg cagatgtact ctgaagctct tcccaccaag tttttaactc 2532841 tgcttccgtg ggtataggtg ccctaatatt ccactctgct atatatgagg gagttccatc 2532901 accattattc tggacaataa aatcctttgt gggatcagct gttgggtatt taaaaagaat 2532961 agcttcacct atattcatcg ttacctccta aaatcttgga tagtttcggc ctccaagttc 2533021 ttgtatatca aaaaagttaa atacaccatt tttatcatct actgcccttt tcagtgtttc 2533081 gtctcctccg taattacagt agcaccagat ttcaacgtaa tctcctttat tcatgggtac 2533141 agtcgcattg ccgtttaaac caagattcat cccattatcc ttttcctgaa agtctcctct 2533201 tacatggtgc agtgttttat atgcttttcc atttaggtaa accttcaaat gaaagtttat 2533261 ataagatgta taatttaagg tatatatact tgccccgatt aagtacattc catcgttcgg 2533321 agcaataaat cgattgtttt tagtatcaaa agcattatgg ctatccttga tgaccctgtt 2533381 aaatgcaatt ttagtgtgat caatcttttt taaatactga acacctgtag ttccaatatt 2533441 cgcatgagca aaacctgata tcttttgcca cggagtccag cctgaaccac tccaccagtg 2533501 tctaatccaa actcctgtac tgtcatagta agtcccagac tcattccctg ttccgtaaaa 2533561 gtattgagtg aaacggtaat tattatattt ttcatttttg acaatgccat aacccaaggg 2533621 gtagcctgta gtatttccct gcccaatgtc cattaaggtc agtcctaaag gatattcttc 2533681 ccctcctgtt cttgcatctt gaatagcatt gtctccagta attaacgtca gattgttatt 2533741 tttatagttg gtatccacgt aatattttgc atccgataaa gccttatccg ctttttcctg 2533801 agctccgaca attgtttctt ttgcattcca attctcccgt tccactggtg taatgtgccg 2533861 ttgtaaatca ttacgatgct cttcaaattc ttttttcgaa gcttgctgta cattatcaac 2533921 gttccctagc ccgatttgcg cctttgttgt attgtgaggg ttgttcatgt catttttatg 2533981 tacagctaaa tctttatgcg catcttgaat gcctttctcc caacggttca catcatcttc 2534041 attaatcgga tcgtccggga gccaatctgt ttttgcatca taagccattg ttaaaccacc 2534101 tcaaaagtaa tcctaaaatc tagcgttcta ttattactaa cgtctaaatc tgttgttctt 2534161 tccgtaatca cgttgttttg atcatcaagt atctgaacac tcttaatatg tttgatgtct 2534221 tcctctcgtt gagtaagcac cgtgacaacg gcaccctgaa tggtgagttc cacaatttct 2534281 gtttcatttc cattcagcag cactttcgat attctatttt tcaaatctgc agctgtacgc 2534341 tctctataaa gctgtgtaat catacaagga ccacctcgtt attattgagc gtgacggaat 2534401 aacctacctt tagctcactt gcttttcgat accttctgtt attcaaaatg acagtatctt 2534461 ttatttggag tggctcattc aaagcagctc gcaaggtata tgccaaatga gctggcttca 2534521 tattctccaa tgtttctatg agctcgctca tatgctgcat atcatctata tcaatatcaa 2534581 ccttaaaacg gtactctccg ggaagcagcc gaacctgagc tgacggattt ttcaggaacc 2534641 ggttcaacgc gtgttcaatg gccctatatg ttgccggcgg tatattggac attttagaga 2534701 ttaggcgcaa tcggcggatc tcatcggtgt cacctgattc ccgcggtacg ttcaaaatct 2534761 tttcccatcg ttcaagcccc caggttgccg tagtaacaaa cagctgatct gtcagatcaa 2534821 agatgctgtt attttgcttc tcaaattccg gagcttccgc tttaagaagt tcagccattt 2534881 cctttaactt ggtaaggaac ggcggcaggt aagcagtcat ttcatcgagt ttgctcaatg 2534941 atgttcacct gccccaattt agggatttcg acggcactca gaaccaaatt ttcggccacg 2535001 ccgttgattt taatatctgc gtaatcactt actgaaggtg aattgtagac gatattatta 2535061 atctgcgata aacggatgac gttatcttca aaggcaatct ttttaaaaag atttaaaaca 2535121 cctgattcaa tttcttgctt tacctgatcg atagagctat tgacctcggg aagtacctcg 2535181 gctgaaatct caacctcttt ccataccgca ctctccactg tgacaaaggc acctattggc 2535241 gcttgtccct caccttgtcc gggttcagga tcaatatagt ttttcacctt tgatattaaa 2535301 atatcggaag caggttccaa gttagcattg gtcacgacaa ttttgactgt accgtccccg 2535361 ttccaaagcg gaaagacctt taccttcccc actccgtcta cttcttcagc ccattgttta 2535421 tagtgtgctt tattggcact gacagcttct cgacgcacgc gggtaaaata tctagctctt 2535481 aaactgtcat catcctcttc ttcacgtcca ggaatcagaa tctctttcac aatcgctttt 2535541 tgaagcccag gtatagtgtc taatgacaat agattctgac cggatatgtt tgcgttccct 2535601 gcttcccccg ctgtttcaca ctccaacgtc ccgtcagctg tgtattgaaa ataaagatta 2535661 tcaacataaa agcgagaccc tacaggaatg gtcacgcctt cagtaaactc ccctgccctg 2535721 actgcttttg tggcagcagt ccgctcaatg cctgcttcag tagctcgtcg atctaaaaat 2535781 tccccttggg ccgtgtctga gaagacaagt tccagaacag tatcgagcca aatataagac 2535841 ttggccaatt ctgcggctac aggagctaac gcgttataaa tcacgctgcc ttccctttta 2535901 tcaatgtccg ctgaaatgct gttcaacatt cgatccataa tcgattcata ggtttgatct 2535961 tcaaacatcc tcgccaagca cctcctcgat ctccaatgtt ccttcgtcag tctcgactgt 2536021 aaaggagaca cggaacgatt cgccttgttt ttctatttca aaatctgtaa cagcagaaat 2536081 ccgatcgtca tagatcagtg cttcctctat cagccgaggg atctccattt tcttatatgc 2536141 gtctgttgtt tcgttatctg ccagcacgtc ttgaagttca tttccaatgt catgactgta 2536201 aacagaatat gcgtatcgct cagtatggag agacaaatat acaaactgct tgatcgcttc 2536261 aaggcctgtg atgatttcat ttgtgatacg gccattttca aaatctattt tgtaggtttg 2536321 cgaggtctct atgacttcgc tgtcatcttc tatatcctca aactcgattt ccggagacaa 2536381 agccattcca aacacctcct atattttgtc gagaataaaa aatgattgcc cgccttttaa 2536441 ggagacaatc atcacacgct cacctgtatt taatgcttct tcaccggccc gcagccgctt 2536501 tggaacaata atcaaatcag caggtattat taatttgtca ttttcattaa gccttatttc 2536561 aacaggggaa acggaaacca cttcagccgg tagaatatcc actggcgact cagaatcaac 2536621 tgcacggaca gccaaatgtt tgattgcttc acttaatctc atgaggaaac accatcaggg 2536681 atagaatttt tctcaaccac atcaatggtc atcgtgtgtg tcgatccttt aaattcgtgt 2536741 ttgtctgtat cgatccagta tgttttctta accccgactt ccggaattga gatatagatg 2536801 ggcaacccgc tctgaagatc cggaatgcca atcgcttgaa tactcttgag ttctttttta 2536861 acaccttttt tctgtgcctg tttgactttc gcacgctcct gaagctgcgc ctggttaatg 2536921 ttatcagaaa ccgtttcgac atactgaagc acaccatatt tactgatccc tgagctgtca 2536981 cttgcagtgg ctgtgtatgt tttattgtct ttctgccggc ggagctttac ttttgtggcc 2537041 gtgtcattaa ttgaagtgct gtattgatag ccggtgatgt tcacacccgt ctccaacacc 2537101 catacttctg acagatctgg ccaagcgcga aggccaagct tccccttcgc agaatataat 2537161 tgataattcc ttccggtttg gcttttcgtt tgtttcaagg cttttagaat catgtcataa 2537221 aggctcgtat catctttaaa cactaatgat ttaatggtgt aacctgtatt tgcaatggat 2537281 gtagtcggaa tctgaaaatc tcgcgccaac cgttttataa tctcgtctgc acgttgattt 2537341 gagaaaacat aaacatcttt gttcttgacc aaatattgca gcatatcata agccgtaaaa 2537401 gtcatccagt gttcttccgg attgcgagaa aacacaatgc cccggaacag ttctttgccc 2537461 ttccacttaa ataaaactgt atccccttca gatacgctgt aatatgaatg ggttccctgt 2537521 ttcgtaatga tcttggccgt aatcgatcgc ggcgcctgat accgttgccc ttcgagggaa 2537581 acactttcag ttaccagctc aagccattcc gtttctttaa tgacgaaaag ttctatcatg 2537641 tcatcacctg cttactgcgg tatttttaat ttttgcccag gaaagatcca gtgtcctggc 2537701 tgtcttatat tccgtttgct tcgtttgatc atagcctttt tattgacttt ccatatcttg 2537761 cgccattttg tactgtctcc ataaaatttg ccggcaaggt cccacagtgt atcgcctttc 2537821 ttaacggtgt atgttttagg agctgattta gatggccgtt tcttcttcgt ctttttcttc 2537881 tgcttgatct tccgcggcga agcagttttg tattccttca gctttatttc ataatcacga 2537941 tcacctatat ctttttggcc ctctgtataa gaaaaaacct cgatactgca agttaaatta 2538001 attttcgttc cagtaattaa gaattgaacc ggctttttag atttcaccca tttctcgatc 2538061 tttgcaatag cattttcagg agaaggaaat cccttatact cagcaagcgg gctgtgtttc 2538121 tttggaaaaa aagaagagaa cgaaatttct ttcgctcccg gtttatcaat aaaagtgatc 2538181 tccccaaaac tagccacttt tactgattca ttttgaattg tgttggatat atcaatttgt 2538241 tcaggaagga ccggaagccg cagcttgtcc ttcccttgtg aaatccagaa ttcatatatg 2538301 gatttagtca aaagcaacga ctcccttcgt tccaatgttg atatcctgtt caagctcatc 2538361 gacaagggcc tgcttaatct tagctacaag actgttcatg tcttggtcat tgtgaaaatg 2538421 ctgatcgcca ttaaactgaa taatgacctc tttgccacct gcagctttaa acgttgtttg 2538481 attacgaccc gttgtggcag ctgttacctg acctgaagat aattcagttt gacctttttc 2538541 agatgggtct gtgacttcca ttccgagtgc cttagctgct tgggctaata aataacgtcc 2538601 acggatgcct cgctcctccg gaatgatcca ttcccttttg tttccttcac cgacacgggc 2538661 aatctgctct ttggtaataa gtccgccgtt agcgtagcca acatatggac ctccatgtct 2538721 catgcttcta atgcctggta cattattaat tgatccatat ctgcttttga tatagccaat 2538781 cgcagcagca gcgttgtgaa tcgggttaag aatgttattc atgcccggca atttgtgtgc 2538841 gttgaaggta cttgggattg tctgcatgag cccctgagat ggatgtcctg ctttcgcatt 2538901 actatcccat aagttgattg ccttcggatt accgcctgac tcatgctgag caattgtcat 2538961 cagccctgga agccagctca tcggtgtctt tgtagccatg atagcagcca tgagccattg 2539021 cttcacattt ccgcttactg cgcccattcc agaataagcg gcagctagtg agcctgcttg 2539081 tttttcagca aactttttta catcaacaga atccagacct tttacaatac ctatagaggc 2539141 aaaacgccca agactcatca tgacacggga aggtgaatga atatccagct cttcacgaaa 2539201 tgccttctca acttttttcg ccagttcctt ggcagcctca ttgacttcac ttgccttaga 2539261 agtcatgcct gaaacaaaat taccgatcat accgcttccc catccgtttg atgattcttt 2539321 agagcggata aacggcttgt taatatgagt gctgacgtat tgatcagtac cagtttgtga 2539381 gctattttgt ccggaagcaa aacctttgat cgttccgctt ccccatgatg aagatttatt 2539441 aacagtgttc tgaaatggca ttttaacctt cgtctgcaag aagccatctg taccggtcga 2539501 agtgctgttt tgacctttag cataaccatt gaccacttgc tttccgtaat tcggagaata 2539561 agagattaaa ttgttcattg gttgtccaac gtttttctgt ttccatgctt ccatagaaac 2539621 aacattatct ctaattcctt gatcaaagct cttcgtgaac tgttgaccaa atgatgttgc 2539681 ttgttcatca agactggatg tgtcaataat aggagataca gaagcagtca ccgccgcact 2539741 acggactagc ggggaagttg ccggttcacc tcctgcagat gaagcagacg ctatatcatc 2539801 aaccacactc atccctaatt tcgaagcagc ttgagaaagg agcattttgc cgcgaccttt 2539861 attattctca acagggataa cgaattcttt accagcttca ccaatccaag atattgttgg 2539921 cttcgtaatg taaccaccag tagcatgttt ctttggcttt tcttttcccg aaccaaataa 2539981 ataatttacg ccactcttca catatcccca cgctttacca gcagtttttt tcgcacttga 2540041 agctacttta ccaccaactt cttttacccc gcctaaaata ctgcttccca attcctttac 2540101 actctgccac ttttcagacc accacttctt actaaaaagg gtttctgaga tggaactctt 2540161 aacacttttc catattgatt tagcattgtc ccatttattt ttggaccagc tttttacact 2540221 ttcccatttt cctgaccacc acttctcgct aaatagagtg gatttcagct ttcctttaac 2540281 tgattgccaa acagaagacg cgctgtccca cttactttga gcccaacttt ttacgccttc 2540341 ccatttacct gaccaccact tctcactaaa caaagtggat tttatttttc cctttacgga 2540401 ctcccaaaca gatgatgcac tattccattt gttttgtgcc cagcttttaa cgccagacca 2540461 cttttcagac caccattcac tattaaataa agtggacttc accttttctt ttacattaga 2540521 ccatgtatca cttaacccat tgatggaagt cttcgcatta ctcttaatgc ctgaccattt 2540581 ttcagaccac catttttgat caaataatgt actgtttagt ttcttcttta cttctgaacc 2540641 atcaaacgct ttacctaaac ttgagccgcc catggtgcct gctataccac caactaatcc 2540701 accaatagct gttcccactc ctggaataac actgccaata gctgctcctg tagccgctcc 2540761 agcaaggcca ccgccagctg atccaatttt ttcaccaaca ttatctttat tcatcccaat 2540821 taaatcggtt gccgctaacg ctgttcctaa tagagggact ccctttgcaa acttgccaac 2540881 acttttcaga ggacttaaga ctttcccgaa cttcgatgta ccgcctgcag ctctaccagc 2540941 tgagtatagc tccgatctcg tagtgattat tgctgatctt gaatctctag ttggattagt 2541001 acctacagtt ctaccggaac gccttctctc caaccgttca gatgacacag caattgaact 2541061 atcagaaggg ttcattcggt ttggattacc gcgtcgacct aaaactcttt tccctcgtct 2541121 tctacgaatg cgatcatttt tacctccatc gctacaacag caatatgtca agctgccgct 2541181 tcgaggtaaa ctcgttggac ctgtggcagt tttggattct ctgccccttg tgctagcatt 2541241 acgattactg tttctattcc tcctttcact ttgcgtatta gtaccagctt taggagtacg 2541301 ttttggaatt aattttcgga ttacgcctgc tgcatcactt ccgacagtac ctatgccttt 2541361 taacagcgga cgaagtattt tcaaataacc aatcaatcca attaaagagg ggatcacaac 2541421 tttaatcgct gttttcaaat catcccaatg gttgacgctc cactcaatgg ctacgtttaa 2541481 cttatcacct atctcctcac ctagatcagc aatatctttt ttgatctctt taagtttttc 2541541 ctgaccttct ttactgttaa tgaacgagct gattttatca aaggccggtc ctaatccagt 2541601 tagcagagag gttcccatat ccttagatat gctttcaaaa tctctcatgg catcattaac 2541661 cggtgtcatc gggttattat cccgaagttt cgtaaagctt cgttccaatt caccgcttgt 2541721 tttggcactt gtaccaatac cctcagccat atctaaaata ggctgcttaa ggtcttcata 2541781 ttgtgtcccg ataagctcag tcgcaatagc agcccgcttt gttttgtctt tcactttaga 2541841 aagggctttt gccaccctaa ataaactttc ctctccgctt attgaaccat ctttgaagcc 2541901 cttgaacatt ttcttagttt ccttggctcc gaacagtgtt ttaaatgcgt ccacttgact 2541961 atcagacatt tcggttcggc ggatgttaaa ctcacgcata ctatcggcta ggttatcgaa 2542021 gtttctggct ccaccctttg ttccttttat catcgcgttt gcaatttggc cgcctgtgag 2542081 cttcaagtct ttaaaggtgg aactgtattc attcatcgtg tctaataaat catcagcctg 2542141 gtcaccggca ttccggtata cataagcaat taagtctccg ctttgtttcc cagacaattt 2542201 caagttgtta tacattgaac tgaaagcacg atctacctct gcctgatcag cattcataag 2542261 ctgggcaatc ttacttgatg actcagtcaa ttcagccaga gcttttttag acgcccctgt 2542321 ctgttgcgat aagtttctta gagataaact gacttcttcc cgagaactgc ccgctttatt 2542381 gttgaaatag atctgatccg tcatttttgc aacatctttc ttattaacgt ttgaagttgc 2542441 tgacacataa gcatcctgag acattgtgct tttaccagaa cccataattg aacctgcaga 2542501 aaaaccacct gcaactgcca gagtaatggt agcacccttc aagctgtcta ttttcgcttc 2542561 aatagcatcc agagccgctg aagctctatc cttaatagaa acagttggct ctgcatgttc 2542621 gctatctaca tcagtcacat gacgacggat ctcatctaat tggttagaag catgatcacg 2542681 tactgaaaca gttggctcag cgtgcgagct attcaaatca gtgagacctc cacggatcaa 2542741 acgaaaacgt ggtgtagctt gatcatttac ggaaaccgtc acctcatgac tgccttcggt 2542801 aagatcctct gcttgctggc gtatagaatg taagccattc gaaactcgat catctaaacc 2542861 catttcaagc aatcgagccc gagccgtcaa acggttggct gatcgatcaa tttgccgcat 2542921 aactctttca gtccggtctt cagcctcaaa aataagaggg ccattagcag ccctcttaag 2542981 tctttcagca ttgccttgta tcattcgaag cttgcgggaa atcttatcat gtaattcaaa 2543041 cgtggctgtt agtttagcca tagttaatta cctcccttct tcgcttcttt ttctaacagc 2543101 tcaagcttaa aaccgattaa tccatataag agcgccttga atgctttcgg agcctcatat 2543161 agttctctta attctgacgg ggcgtatttg agctcatgca tagcatagta aaggtataca 2543221 gcctctttgt ccccgtcttt tactagtttt ttgctgcttc ttcaaggtct tcgagatcat 2543281 catcaaaacc gttgatttca attgctttgt tcagccaatt tgcatattca ccgccgactg 2543341 aaagaacacg tttggcgact tccactggat cttctgtttt gtaagcctca cgtagttcct 2543401 tagctttaaa gttcggataa acagtcgttt caaccgcaat acgagcataa aagcgttggc 2543461 tgtccaactc cttcacacgg ccgcggcctt ttacattttt gtaagtggtg ttctctttct 2543521 caagttcgtc aattcgttca gtcgtaattg ctttgaaaat gaatggaaca acattgcctt 2543581 ctttgtctac aaaccgttta gaaatcggaa cttctacctc ttccgcttca attgtttgtc 2543641 ctggcataaa gaatgaaaga tcgtatactt tttcgttttg tttttcactc atgtttatta 2543701 actcctttta ctttttagtt ttggacaaga aaaaaagcac attcatactt tttgaatgtg 2543761 ctttccatat aattcatgta taatagattc ttgaagctac cttagcttat cctccgaata 2543821 tgaaaggagg tgaaattatg tcgacctatg aatctctaat ggtcatgatc ggctttgcca 2543881 atttaatagg cgggattatg acatgggtaa tatctctttt aacattatta ttcatgctta 2543941 gaaaaaaaga cactcatcct atttacatta ctgtaaagga aaagtgtcta cacgaggacc 2544001 ctcctattaa agggtagttt cttttttaaa agctagagtg ctgccacact ctggctttta 2544061 tattttagca tttctcatga aagtaacaca cattaacaag tggtaatgtg gtaatgtggt 2544121 accaactata agcttacgcc agtagttgca atacttttgc ttggcaccat tataacatga 2544181 atatatattg attatataat tatttgtatc ttttatttgt tacttttttt atctatgagt 2544241 tcaaaatgac ctgatcatag aagccttaac cctttttctt ttattaaaaa ccctcggatt 2544301 atgaaagtgt tatggtacaa tatggtttag tataaatgaa tattggcttt caacatctca 2544361 agggcggtct ggctcactcc ctcatgaaag ggggtgatgc acgtgtcaac atttcaagca 2544421 ttaatgctta tgcttgcttt cgggtcattt ataattgccc tgttgactta tataaagaag 2544481 aaatagaccc accccttgag ctcggcaaag taaaagggta aagtctatcc taaatacttt 2544541 catgaagttg ttaagccagc cctcttgatg ggccaacatt tatactgacc cggcggcaac 2544601 cgggtctctt ttattttatg catttctttt gaaagaaata catgtttcca tttggtacgg 2544661 ttgaattact tctaaagtaa tcttaccaca ttttttcgta aatatcttcg ttaaagtcgg 2544721 cgatttttcg tgaaagtgat tagaatgtgg attttaactg ttcaggcaca tcaaaatcct 2544781 caaaggtaaa cggcacttct tcttccaatg cttcagaatc aacatcaagc ccagcgattt 2544841 tcgcagaatc aaagttcaca tcgtacaagg tgactcgttc agtcccacga cctgaagagg 2544901 cgtcatctag aacagcttgt aaggtgaaat aaggatcact tccctttttc acatagtcca 2544961 tcataataag aacaaattga gaagtcactt tataaaaagt ggctgttccc gttccatttg 2545021 ctccggtcgt tttgtgcccc gtcatccgac gacccatgat attgacctcg gatttgtttt 2545081 tctctacatt ggcttcaaac gttttgatat gggccatttc ttctccatca agaaacaacc 2545141 tgccctcttt acctgaaatg gtgttttgcg cttttaatgc cattcctatt tcacctcaac 2545201 attaaagtag aatttttcag ctgcatccac cggttgaact gcaagatcaa tcaggaagcc 2545261 gtcacgatca ttattcagag caattgtaat gtcattctct gaatcaaaat cagtaatgcc 2545321 ctcgttatct tgaagaacac tcaagtattg agtaattagc gtttttacaa actgcagtcc 2545381 gtcatttgta gcgggaacat cactgccgct cgcttttcga gacttgatca atgctttcaa 2545441 ttgtgatgtc aggtcattat tgattgcatc aagtacacgg acaattttgt ttttctggaa 2545501 catcttattt ttctctgctg ttaggcttgt gagtgaatta atgtcctttt caaccgatac 2545561 tgatttatca cgagaatcat aagtaaacaa gaattcccca tttgacaatc gttcaacgat 2545621 ttcgtcgttg tcaattcggt taaggacatc tacagctccc tcgtattcta caaatgtaag 2545681 tgattgatta aatgtagccc ccgcacttgc accggcaacc caagctgtag ctttttcagg 2545741 agtgatctcc gttccatcct caagtaggac accacctgtt acattgataa taccctcatg 2545801 gtctcccttg taatttgaaa gaacaccttg aaccttttgc ccttggttgt ctctcagccg 2545861 tttgataaac gcaacaaacg ttgcttttaa ttgctcgtta tcctctacag gtaaagcgat 2545921 tgtgtcaaag tattccgttt cagccgcttc caagaaagct gtataatcgg catttgtcgg 2545981 tgttttgtct gttccgcctg acaagcggat tccggaagtt gcagggagag caccgctaac 2546041 atcttcaggg gccgtaccgg ttaacggaat agtaactgtt aaatctcctt tccccgtaaa 2546101 cgtgacatat ttattcggtt taagttcttc agctttagac actgtttgtt tatccacttc 2546161 agattgatca aggtaggtag tgacatcaac tttcgaagag tcaataacgt tctccgtaat 2546221 actaataatg atgtcattac ctttagtgcc gccataaaga gcagtagcct ttacaccttc 2546281 gctaatgtct gctgaagcac gaagaccttc cgttaggcga taaagcaaga ctgtattcgc 2546341 cttcttcatc gcctcacgta aaagcaacag cgaaggatca tcaatgttca accccacttt 2546401 tttattcaag tcctcgattg aagagataga aatgaatttc ttaacctcac cccagctgga 2546461 cgctatcggc agcgccactg ttccacgttc tccggcagaa acacggttct ccgcggtcgt 2546521 tttgaagtta aagtaaatac cggcacgctc tttttccttg ccaggtgtga aagttccgcc 2546581 gttcatctat ttgacctcct tttgaagaaa ctgagaaatc aacttcttcg cttccgattt 2546641 tgtaatactc attttatgaa catgaaaaag agcaccgtca aacacctcgg gttttacccc 2546701 aaagagctct cgactgtgct ctcgcaaatc cttaatataa aaagcatttt ctgctttctc 2546761 ttttttagtg gccatcattt caccccactt ttaaatttaa aaccatctat tgaacgctga 2546821 tcttcccgct cataccaata gcggctcgtc cagtttaaga caatggtcgc ataatcgtct 2546881 gatacccgcg tttctattcg agataggcga ataaaatccc cagtatcctc gccagattct 2546941 tgtataagcg gaattatgcc tcttctgctt ctaagtgtat ccgcaattcg ttccgcttcg 2547001 ttatgagcct tctgtacgtt ttcgtgaaag agttttacgt ttaaaacata tgctttctga 2547061 aacgtggata ctgtgtccac cccatcgacc gtggaagccg gtggaaagta aagagacgga 2547121 acagcaaagt cctgcggtat ttcttcttca tacacttgaa caggatacag tttgtataga 2547181 tagcccataa ttgaacctac ttcttgattc atggcagcac cgccttaaaa ttcttcataa 2547241 atccattgct gcagcttccg ctcaaggctt ctctcaaaca tcaactgaaa aatggccatg 2547301 gcgttatccc aaaaccccga accgtctacc catcggaact tcagcagcat gccggaattt 2547361 ttttcagcag ggtcatattc gaaacggtcg cctttccacc gacctggaac ccatcgtcta 2547421 tcctgatttt tagacggatc gatagtaaag tgcccgtcat tgacgtatga ggcgtaatcc 2547481 agatttgttc caacatccaa ctttaagctg ccttctgtca ttgaaaagat attatcctgg 2547541 tcacctttct gaaaggaatt gagcaagcgg cgagtgtcca cggtcttcgt cctaatgatc 2547601 tcatcttgga tgatatctaa gaactcaaaa cccattgatt caagccactg ctcatatttc 2547661 ctcttcagtc ccccacgaga agcccggtct aatgattgta tgaactgatc gagaccccga 2547721 attttcataa gtattcaacc tcccgtactg ccgtcacttc ccaatgatga ttcctgattt 2547781 tgcggggctt ctgtaattta taagcagtac catcccaaac cgccctgtca tttactcgaa 2547841 tatcagcagt agcagggaaa tgcacaagga aagattgata aatagataca tttgactcct 2547901 gttggataat ggactgactc ttctctgtaa aataacacgg ctgattttct atgtccggct 2547961 catcagggta cgaaaaaacc ggttgaacat cttcaaccgg caccccgaat ttttgctttc 2548021 tattttcttt tttctcctgc agatggtaaa tgtcacatct gtgagtcaat aaggattgat 2548081 aactcatatt gatctcatcc gcactttcgc ttcaatccct tctaaatcag ggtcagccgg 2548141 tttcacataa tcttttatta atgcatacac atcaggtttt tgaagagaac tgccatcccc 2548201 tagagtataa gaatagtcac caattttttc agttgtatat cctttaataa ttgactcgtc 2548261 gccatttata agagcataaa actgagacaa ctttaataga gccagtcgaa ccgtttcagg 2548321 caaagggata tactctgcat ctgaaaaatc atgtccaact ttaagaatga tatcggcagt 2548381 tgcctcaagg atatcctgtt ttaacaactc gtcaggtctg gtctttacag actcaaaaac 2548441 tgaataactc tttaattcat cgggagtgat taacagcata ggtcactccc ctttgttatc 2548501 tatttgctta aggatgtagg caattctttc atctgcgttt ttgaagtcag acggattgcg 2548561 accaagatta gaaataatgg attcatgctc tgctttattc atacctttca attccgattc 2548621 agtataattt atcggatcat ccttttgatt attaagctct tgggttagta taaaatatgg 2548681 attttcattt aaatactcat agagcttttt cggtactgtt tgactgacac ctgctcgaaa 2548741 ggttattccc atcacattgt atgttttgcc tttaataagc tttgcagtaa acacaccaga 2548801 ccacctactc cttcactttc acgatcttgg ctacggcgtc ctcttcttca aaaacactat 2548861 ccaatttcgc tgtcaaaaca atgataaaca tacggcgacg gatgtcctta tctacttcaa 2548921 tccgaatgtt acgagagaat ccgagaataa tattcttcgg atgagttagg atgatatcag 2548981 aaacatcggc tgcagtatct ccctctccaa tcgtataagg ctgtaaattt gcaatacctt 2549041 tgattggaac accaaaagca gatgaaaggc caccttgaac agctgcatcc cctaaatttg 2549101 tttgacgatc agctacacga tctttccatt cgacctcaat accaggcgat gtatagaaac 2549161 ggaactcctg cggaattcgc aaatatttag gaggtacagc tttgtatcct cgtttaaatg 2549221 tttgacgtgt cagttcctca cctgcagcat cgacaatatg agatgtagct tgttttctga 2549281 tgccatctaa ttgtgcaaga tatgagtcgg aggaagatgt atccccattt acaagcaact 2549341 cttcaatatc aaccgcagca cgctcagcta tcatttgcat gattgtattc tgaaggccat 2549401 ctttttcgat gttgttttca agtgtgtcat aggtaatgtt aacttcagca attacttctt 2549461 ttgtgcttaa gttaactgtg ctagttgatg gaactgactt ttgatcttta gttagcgcaa 2549521 ctccctcttg ggctgccctt aaaatacgct gaccaaaacc gatcttctcg attttctgtg 2549581 tgtcatggtc catttgaata actcgcgcat ctcttaaaat ggttggcgta tcttgtacca 2549641 ttcgaataaa agttgaagcc tgagtaggat tcataatccc gccgctctct aaagtagaaa 2549701 gcgtcatttc tgctttatta ataacctctt gatttctcat tcgtatcctc cttatccatt 2549761 aaaacaaccc tgaccagatt gatttttgaa cttgttcgga acccgattct tcagtttgct 2549821 tagatgttcc gcgacttttt tcgattgctt caatacgatc agcgagcggt tgaacagctt 2549881 ctgaaattgc ctttttcaac ttctcgccct ctttttcagt ctcttcttct ttttctttat 2549941 ctttcttatt aagctcttcc tctttttcta atgtctcgag ccgcttctta attggctcta 2550001 atgcttcttg aatggattta gttacttcct ccgaagtcat ttcttcttcc ccctcttttg 2550061 tttctacctg actcagtaaa ttaccaaggg cagcatgagc attcttaatt tcttgcaggt 2550121 ttgaagcgga aaattttctg cccgcctttg caactggctc ttcatatgat tgctgttgtt 2550181 ttccaacaaa aaagtttttg agcaaattaa atagcccttt ctcatctgtt ttctcttgag 2550241 aaacgggctt ttcttgtttt tcaatcgtct cagcagttcc tgccattgaa taaccggtaa 2550301 tttcgccttt tttgatttgc tcccatactt cctcagaagc ctttgtgaca aggacccatg 2550361 atcccttttt aatggtttcc ccattcattt caaagtctgc cggtgcgaca taggactcaa 2550421 ccacctcacc aacaccaccc tgaaagtcat gttgcttgtc gatttgacga gcatctttca 2550481 ggaatccatg agcggccttt tcgatttctg cagctgtcat gaaatctccg tgggcgtcca 2550541 ctgtatcagg ttcatacacg ataccgtaaa caagtttttg ctcgtctgcc tctttcgcaa 2550601 ggattctgac ttccttttga aaatcaggtt gtttttctga tttcacaata aagaactgct 2550661 tttgattagc agccttatcc acataagaaa catgtgtgat ttttgcgttc accaattctc 2550721 ttggcatgtt attcacctcc ttaaaataag aaaagacttc taattagaag tctcaccagc 2550781 tgtattctca gcaacataat tgcttgttat ctccattaac ctttttacac tcttatctac 2550841 attccagaaa aatttattca taatgtagct ttgtgaaata tgacttttct ctaagtcatg 2550901 aactatattc attatatcaa gtaagctttc cgcaaatgaa tcattaagaa ttttatggcg 2550961 tttcaaataa tcaaccatgt ataacatgcc tataccttga gatttatctg ccgcatcatc 2551021 tttttctgat actttttcat aaagattttt cactgctcca tataaacgaa tcatttccat 2551081 ttttagtagt aagtcattat cccctttaat gcttgtcttc tcattataat gggaatgtgt 2551141 ttcctcagtg atttcagaat tactttctaa atttaatgaa tcttttagat tttgatcatc 2551201 agttccatat tgattctctt tattcaattg gaaactaatc ttatctaatt tttggtcaat 2551261 agtgaattca aattcccaat ccttatattt aattttcgcc aaggtactga tcaaatttga 2551321 aaccggttgt tttaatttaa aaaccaagat aattattgct accggccaaa tgattgattt 2551381 gactattgaa gagataaact ccatccaatt catattttcc ccacctaata tgtaatgagg 2551441 acattatact attttattcc atgtttgcta agacttctct ttgaatctct tctttttctt 2551501 cgggtgataa gcctaaaatc ttactatcta ccacaggcga tagaacacaa tggcagttaa 2551561 cccgctccct tgttgatagt ttaggatccc tcggaaacat gcaggtttcg ctactgcccg 2551621 gtatctgaaa ttcttcatct actccaatga ctgtaccgtc aagatcaatg tgattttcac 2551681 gaggattgtt cttcttccct ccgctgtgcc gccatttctt tttctttact gccggcgatt 2551741 gtgcatatga ttcatgctgc gcggcagagg aagcggcaag cacttctgtg atggctgtgg 2551801 tacgcgcccg ctccctatca aattgtggca tgtctttgag agtcaactca atgtcctgga 2551861 ttgatgaacc gttctcgata gcattagtta gcacgtcctc caccacttca tgtgtgttta 2551921 acttcatgat ctcagccagc ttctttgacc aatccttaat ccaattaatc gtacgattgg 2551981 ataagacttt aaaaggcacc tctggatcta ttgaatccat gattacttca gccatttctt 2552041 caatagtctg ttgcaggaat ccctcagtca gttcctgaaa ttcttcctcg aagtcatcct 2552101 ccgcgaatag gttctgagta aaaaacacta gaagggcttt taacgtctct tctgagtctt 2552161 tgcttacaaa acctttgaga ccatctaaaa acttcttatg ctggcgtctg agcaatctgg 2552221 caatgccttt ttcatattcc tccacatatt tggggatatt agatttgcca ggaaagtcag 2552281 gtaccatctc ccccaattgc ttatactgat tttcctcggc tttttgaata aagacattta 2552341 aactctccaa tagcttatcc gttttgttca tctcttcaaa tcctccagaa catcccgcat 2552401 atcttttaat aacccgatca tattaggagt accgttctta gatttaaaca gtgcagccaa 2552461 aggatcggaa acggacgact cgttagtttt accaagcggc ctgttgtatt cttcttctgg 2552521 ccattcttca agcgtcttac caagtacccg tccagccaaa tcgcgtaaat cattcggaga 2552581 aactgcacct gctgttataa acggtgttag aaccttagca atttctaaag gatctctaaa 2552641 gtctggccct tttagttgga gtcggacttt atgaatttca agatcattta gaaataaagc 2552701 attcagttta cctgtgatta attttcgttc aggctgaaat acttgttcct cagtaatctt 2552761 tcttgctgtg tcagctgtcg ctctgttgta atcttgagct tcacctgtat aaagtggggg 2552821 caaacgaaaa gccgatctaa ttttatctcg gttcttttgg tcatattcaa gaaacaaagc 2552881 atcttcttga aggatttcag caagtgactt aatatcaact ttcactggtg caatctcttc 2552941 atcaccatga atgtttttcc ccttcgctat cccttctgct tcaagtaata gaaacttatg 2553001 agcgttctcc actccttcaa gcccattcat gtaatcctgc aattgtgtgt atgagtcctc 2553061 agacaacatt ccattttcta ttgtgatggc agcgggaata tgtcttcctt gtttgaagta 2553121 cataaagttc agctcttcag ctttacgagc accatacaaa ttaacaatat ggccaatcca 2553181 tcgcggtttc ccataaatac cgcttcctat tttgaaatgg accacttcat ttgctcgttt 2553241 ctccaatggg gtctgttcat catattgacc tgtctctaaa tttaaagtgc gaggatcacc 2553301 atattcttta aaataaacca tacggccgtc aatcatctga acatactttc ggaatcgttt 2553361 ctctcttttg attgatttca tttgtccttg ttcgaagtac gtaaaatcaa cttcgattgg 2553421 ttcagacagt ttgcaaactc gtacattttg aacgtccatg tattcaatgc cggctggctt 2553481 attttcaccg tttcgaatga cctcaataaa gccattgccc gtcttttctc tatcttcaat 2553541 aacaaatccg agtaaagtct cagctgactc atcaaagtga agatatttaa cgaactcttc 2553601 aagctttgtc cattcacttt cagcttctgt tttttcttca tttgtcacat ctggcgaatt 2553661 cacatcaaaa gaatactcga aatcaaatcc aaagcccaca atatttgtcc tgtaggcatc 2553721 aacacattgc tgtaagattg ttgaatactc agcaatcatt tttaattcct ttaggttata 2553781 cggaggaggc aaaatattgc tgtcatagct gtcagcaaat tcatcttcat aaatttgttt 2553841 cgttgattca gtaggtggag aggctttgat cactcgtgct ttaacagatt tttttgacat 2553901 gctttacctc cttcctggtc ttgatctttg cggtcttcct tttgattctt ctttcaaatc 2553961 ggttacctca taatcatcga gagcgtacca gatagctgac agtgtatgcg ggtctatggt 2554021 gaactcgtct tctatgatgt tccccagctt atcggtagca taagcaagcg gcttaagctc 2554081 ataaatcgtg ttctcgcaac gatcagagca aatgatcttc ctgaaccgct tgattttctt 2554141 tgtatactga aggcgtgatc cttgatattt acgggcaccc accatattga aaccgtgttg 2554201 ctgaaaataa cggattgtct ttggctctgc tgaatccgcc ttgattaatt ccttagtctc 2554261 tgcaaattcc ttaagttctt cggctgtctt atcatccgtt aatccatttt tgtaatactc 2554321 ccagtagata tagagatatt tcttttcatg atccacagca accctaacga cggcgttata 2554381 cgattccaca aaaccaaagt ccatgccaac ccgtttaagc gggcggttaa tattagagat 2554441 tgcagtcata acctcttcat gcggtcgctc ttcaaactgc ggcagaaccc gaattccatt 2554501 cacgccaaaa tgacctttcc gcgcaattcg gtaaaggtct ggatcgtatt ccttcaattc 2554561 ttcaagttgc tggacatagc tttctggcag gaaaagatta tcatctgccg ttgagtgatg 2554621 ataataggtg tcgttgctaa cgattatccg cttttcataa agttccttat catccagtac 2554681 aaagcgcttc tccctatcat ccttgaagaa atgcttaaaa gtccaattgt cctctccaac 2554741 tggatttgtt gaaagtatca tgtgaagcgg caatgtcggg tgacgaagac gtccaagaag 2554801 ctccttgaac ccctcatatt ttacttcaga gcattcctca atccaaatga gggaaatatt 2554861 attgattgat ttcagtttgg ctggcttatc catcccttta aagatgattc tgctgccatt 2554921 tgaaaatcga atctgcatcg gagaagatac acatctaacg atatgatcta attttagatc 2554981 acttacaagt tcatcaaaaa gtgaaaatgt tgagtcccta tgtgtgtcgt acacttctct 2555041 gataacaagt gcagtacgct tttctctgag caatttcaga acaatcttga gcgccacatg 2555101 atagcttttg gatgatccat aaccacccac aagaaactga aacttttgat tccagtcaaa 2555161 gagaaattct ttaaaatgtg gatttacctg tttaatcact gtcatcacct ttgtttacaa 2555221 tggtgatctc aaaaggttta tcttcttctg taagttcttc gatctctatt tttttcttgt 2555281 tgatatttaa gcgcatatgc tccaatttaa ggcgtcgttc gtcttccgaa tgggctaatt 2555341 catcaaactg tttaattaaa ttcctgagct ctgccattgc acgagattga gcgttcaaga 2555401 acgttgcatg acgatcccaa gaaaattgaa attcgaattc ttcctcttcg acttcgtttg 2555461 tctcagatag cacagacttt ttctttttca gttctttaat catttcctgc ttatcagaaa 2555521 cgaacatgat cttttgcgcc cttattattg cggcatattg gatctgtatc tgatcccata 2555581 tcatatcgac aggcgaacgt tcttgaatcc cttccatgat ggatagcgtt tcttctggca 2555641 ggaacttaga gaagaatcca tgagtcacag cgttttgatt tcccttaggt gcgccgccat 2555701 tattacctaa cgcattcttg ttaccgagtg gtgcacctac tttttttgtg tgcacacctt 2555761 tttttaaggg tgcacccttt tttctttgcc aaccatggcg ttgtttccac gatttaatgg 2555821 tgttcacaga taccccatat ttctcggcaa ggtccttgta tttcatacct ttggcgtaat 2555881 ccttatacgc ctgtatgtgc ttatcaacca tctacattca ctgccgcctc cttttagatt 2555941 gagttgtttt gaaaataaaa aagctcctca aaagaagctt aaatatgttt ttttattaaa 2556001 ttagttattt catcaatcaa ccgctcaata tattcttgat tgaagttcac ctcaattatt 2556061 ggatcatcgt tcataaaacc tcttaatgcc acttcaactt ctcttaaata atttatatat 2556121 tcctgtaact tgatattcag ttctttatca aagagtattg aaaatttctt aacaatcagt 2556181 tcaaatgccg atagctcttt aaaataatca gtatgtaatt tttctaagta tccttctggg 2556241 tgattataga acggtacaaa ggcagcagcg gtttcaattc ttttattgtt aatattataa 2556301 atctcatcaa ttagtatata gccttttgtg aaaatttcat ttccttttct attcttcttt 2556361 tgtaaaacat aattagttcc acctgtaaaa aaaactgctg ttatagcact agtaatgact 2556421 gtaccaaaat ctatttgaat caatttcatc ccctcctttt actaattatc ggcaaaagag 2556481 agcgatacag gtactattcg caaaatttgt cgaacgaaac tgttgtataa aacctaaatt 2556541 tagtggtgac gcaggaataa ttcgccgcgc cgacctgcct cccattttac actacagatt 2556601 ttttcagatt caacaaacgc tcaaagtggc aatcttggca taattggctg atgaactcat 2556661 ctttcatttt gcgtacagtt tcccttgaaa tgccaaggtg aagacttatt gcgcggtagc 2556721 tcataccctc catcatgcaa tcataaatga ctttatgctg ctcaccatgg atcttttcag 2556781 cccctaattc aactgcatat actcgctctt cataatactt aagacgtttg aaaagacgtt 2556841 cctctctcat atccatttgc cttagctcag cctgactctt cccaggactt ccttttggca 2556901 tagtagcttc taatccatat tgagcaacac cccaattctt catgggaatt actgaaccat 2556961 agagtaccct ttgcaatcga cgaacctctt tcaccatcca gtgatagcta ttgattagat 2557021 tttcaatttc ttttcgattc atgaaagtat cctccttttc aaaataaaaa cggacaccaa 2557081 acatacagcg taatactgta agttcagtgt ccgcaggctt tccgtcttgg actaactgga 2557141 tattttatgc tttaatgaat tcacattacc taaggaaaaa aattcaactc cctccttaaa 2557201 tatggtaaaa ttttattata aagtagtgga ggttgttata tgagagttag agaaataaaa 2557261 aatttactcg acaattataa taaacaaatt ggagttagtg tttcgcacgt accgcacagc 2557321 aacagaaaga ctgttcttaa tttacaaaag tctttagatg caattaacga gttgtctaaa 2557381 cttggttttt tagatgatga tattgagaga tttaaagatc taggaagtat atattattca 2557441 cgtgtacctg aagataagat tgaagtggat aatcacatcg ctaatcaaat tactaatcat 2557501 ataaaaattg taaaagaaaa attacgtggt tttggaattt taattgatca gtcagtttct 2557561 gatcaaaatg agaacgtaat tagcgtaaaa ctccctcaat acaactcatt agaagaacta 2557621 gaaaaattca tcaaaaaatt aaataatgca tttcagaatg gtattaccct tgaggaaatt 2557681 aatggacatt ataaattaca gggttttgac acaggttcaa tgtggattga catcttagta 2557741 aacagttcag ctgcagtaat atttgttgga caacttatag atgcagctat aaacatttca 2557801 aagcgatctc aagaattact cattactaag gcaaacatcg aaaagctagc tcttcaaaat 2557861 gagcaattaa agctacaagt cgaaacttcc aaagctttgc tagatggaat tgaaaagggt 2557921 attgacacaa taacagatgc cgaaataaaa aatgttactg aaggagcaaa ttattcaaca 2557981 gaatcaatag gacatataaa acaatcggtt aaaatctttg cagaattact ccatgaaggt 2558041 acccaattcc acccatcttt agatgcacct tctgaaacag ttgaagcctt tcctgaaccc 2558101 caaaagaatt tagaagagcc tcaacaatta ttagaaacat tagctgacaa tttacctgaa 2558161 caggaataac ctgcacatcc aagccgaagg aggagatatc ctccttcttg tttacctttt 2558221 tataaagtat tatatcttct tctcatttca ccttaaaccc tatctcatga tcaacccttg 2558281 caaagctgcc ctttacagtt tgaatcactg ttttgccgtg ctccggagca tctaaaacat 2558341 gtgcagttcc ctgattccca tctaaaacaa tgatctgaac ttttcctggg tcaattttct 2558401 gctgaatagt gaagtctttt ttgatgttta tttctcttgg attgtacact caaagcgccc 2558461 cctatgttat gatagaagta ccagttcata tcaagaacac tgaggctaag cgcttcggtg 2558521 ttttttattt ttaggcagaa acctctctta tcatgacttc cacccttggc tcttcgctat 2558581 aaaacttact gactttcaaa tccacaacct gactatcatc tttgtatatc agatgattca 2558641 aagcatcttt cacgcccttt acataattat caacgtcggg ctttgtagtc ggccgcagaa 2558701 ggcccttttc agctttctct ttcttctttt ttgagtttga aactgactta ggcattggtc 2558761 tgtacacttt gacatccatt gagacaggac cagtaataat tgtttctggt cgatgctgag 2558821 acgcaaccaa tgccacatac tgtttgaaat actttgattt cgctggatca cgcatatgca 2558881 ccttcccatt tcgtattgat ccacgcggcc ttccttgtgc gactggctca ccataaacag 2558941 tgaacttaat gcaatccaac tgttctttac ctcccgtcaa gctgttccca taacttaatt 2559001 tctttttcta ttctcggtgc agaaagtaaa attatcagca gagacacgac tgctttaagc 2559061 actcagcatc cgctccattt gctttatttt ttcctcaagt aaacggattg ttggtgtaag 2559121 atctttacct tcatttcgat ttgaagggcc aaatatataa agtccaccag ttgcttttat 2559181 attcgttttc tttttcattc ccaatcacct aacctatgat ttaattgcat tcgatcgcct 2559241 ctaataatca ctatgtaatc acggcacatc tggtgaattc gtgaaccaag agcctcgtct 2559301 atatccaaaa tctcatcgat tgttaactcc gaagaaatca gcaaaggttt gtgatttaaa 2559361 taccggtagt tcaagactga ctggatttgt tcaacctgcc agtctgttgc ccttggttga 2559421 ccgtttattg gtttaaataa atcatcaatg aatagaactt cgacctttct catggcatcg 2559481 agttttgctt ctaagttatc aaagttagct ttcaaatcac ccatgccctc tacataaggg 2559541 aaatacatgc agtgtactga ttttttcttg atcagattat tcataatcgc cgtgagcaaa 2559601 tgagttttac cgctacctgg ctgtccaagt aatgcgatac tgttttgcct ttctcctttg 2559661 atcttttgaa aatctttata gtattccact gcacactcat aagcgtcctt gatcatgtct 2559721 ggcttaccgt ccgttatgaa gttaccaaag agaagctttt caaactcttc tgtaatgcca 2559781 ctagctgcca tgagtctggc aattttcttt cgtcttacac attcacactg ttttgaataa 2559841 gtatctttcc attcgctagc tttatccggc gtacaaacct tacctaacag aaaatcatct 2559901 tccgacacca tatcgtccgg aaccataagg tctaactgtt catctaaatg ccaagaagtg 2559961 tccttatgga ctcgataaac gacaattcca cgatccttac aataaggaca atcaaattca 2560021 gccttttctt ctgatacggc ctgttttgtt cccaaaaagc gggctgacct ttcccgaagt 2560081 tcctgcatga tcgtttgaaa tgcggtgtct atactgactg ctttgtttat agccatattg 2560141 tttctccttt ctcttttgag tgaatggatt tgataagatg gcttgaacat atgacaaact 2560201 tgcagctttc ccctttaatt gaaacgctgt cttgatagcc tccatcactt tttcctcacc 2560261 ataatcgtcg accatgtagc cgatccgctg tgcctccatc gggccgactg accgagcaac 2560321 tttgttttca tatagctcaa aggcattttt cattttgtca tcgacctcct gatgttcaat 2560381 ctgagctggt tccaaagctt tgttcttcat gtaatttcct agttgtatgt agtctgcata 2560441 atgaagtatg gtgacgatga gccctctttt ttgtggaaga cggtgcaatt tgatatatcc 2560501 ctgtttctcc attcggtcta gtgagtattt gatctgtgca gctgaccagt taaaatcttt 2560561 tgctagttcc acaactttga taatggtctg cccaagttct agctcttgat ttggcctgta 2560621 ttcagctctt ttgaacaagt gatcataaat tttttcatcc ctaaactctt tgaatggtag 2560681 tcggggtatg accacatacc ccattgcttt tatgtccaag tcaatcacct acttcctttc 2560741 acagagtgca gttatgtcag agatgccggc tcaatcaaac ggaagttcat cgtcttttat 2560801 atctacaggc ttgccgtcaa aaggatcggt ttcttgggcg cttggttttt ccgtttcatc 2560861 tttgtttgaa ggctcggaat cgataatttc tgaactgtct gcctcattgg taatgtcaat 2560921 ccgttccctt gtttcatctt cctcaataac tgctttttgc atttcaacag agagaatccc 2560981 ccacttgctc aaaactgctt ttaatacagt cttaagagcc atcgcatccc agtcattttt 2561041 ccatccaaaa tcagacttac tgaatttctt tttgtgcttc tctacttgtg cctttgtcca 2561101 gtacactgtt tttcggaagc catttatcaa ctcaaaataa gctgcataac caattaccgc 2561161 gtctgattct cgtttttcaa aatcaatctc gatctcctca gtcaacggat tccacttctg 2561221 caattcgcct tcatgaatcg gtatgcaatt gatggattta tattggcctg ttcgtaaggc 2561281 tagctggata tatcctttgt atccaagctg aaattgagcc ttacctccgt aaggaacaat 2561341 ccaggcatac cctaagtttt tatctatagg taaatcgagt gtagctgcca ccattgctga 2561401 ggatatgacg ctcataggat ctgttttctg tagcatctgc tcgctgttat aaaggcttaa 2561461 gatagaagca gtaaactgtg tagccctctt ccctaacact tcctcaaatc gtttaataac 2561521 agatggtgag gaaagtagcc ctttcattgt tgctccttgt tgttgcacag gtacgttttt 2561581 ttgtttcttt tggatgttgt ttttaattga ttgattagta gccataatca gctaacctcc 2561641 ttgattccaa aacgtctgaa atgagtttcc tttttaactt tctcgtatac atccggaaac 2561701 tggtctttga gctttttcgt gtcaattcga tttgagacaa caggcttcca gcaagcttga 2561761 tagttaccga taaacccata ctctgcatcc ttcatttcat gtttgatttg gttctctaat 2561821 tcttttgcct ggctttgaag ctctgagatc tgttctttaa taagcaagta ttgttgaata 2561881 cgttctcgat tagccgcagt taaatcaata gctttgttat tttccgtttc ggcatatcgt 2561941 tttttgaggt attcctccgc agcacttgaa ccatctaaag caggagcttg tccacctaag 2562001 accttgtcat tccagaactc aatctctgct ttaaagatca tgtcaattaa ctcgtcgtct 2562061 cgctcaatct ctttccagac aaatttgttc ccgccaatca gcacagcaaa ataagctttc 2562121 cgatattcag gtccaagcac acccagataa tgctggacct gaacgatata gctctcgggg 2562181 atttcttcgt cctcccattc ttttaagttg taggctgatg ttgttttaca ttcaaggatc 2562241 gctttttcac caacgatcat tcgatcaaca ttagccaaaa tgaaattata ttctggatgt 2562301 ctgagtattg cttttttacg tctaaccttc ttgccactac gtatctcaaa ttcttttgca 2562361 acaatatctt ctagcaatga tccaaagtaa gcagcttcac tttgcgattc actaacaggg 2562421 acctgtcctg ttttgtctaa ccataattca aaaggtgtct tccacttgtt cagccccaag 2562481 ataatggatg catctgagcc gccaattcct tttcttcttt caataagcca ttcatcacgg 2562541 ctcatttcag aattcttagc aagaacctca gcccgtttgc ttgtcattcc acctaacccc 2562601 cattgttttt attgaggcta tctgataaaa tatttgcaca tgagtttttt tagatagcct 2562661 ttaaagaagt ccactttgcc gagtgggctt ttttattgcg cgtttttaaa ttcaaaacca 2562721 agttgctccc ttagatacct ttccaagttc tctctgagaa tgatttcgcc gccatcaatt 2562781 acataatcat caactggtgt tacttcatca ccgtaaaaat ctatttgtac atccgtttca 2562841 gtcagcttat cgtgccagtt gtttatgacc attggatttt cgaccattct tattctcctc 2562901 tctgaatttg tctgcacgtc tatcccataa cagatggaat tcactattgt tacgaatcat 2562961 cacacaccat ttacgaactt ccagagcagt tgccggttta tgaacaaaat gaaccatcat 2563021 cctatacacc tgctcactac agttaagttg ataccttgct gttgcatttt caatgccgtt 2563081 tcataaaggc gtcctttgtt tgcaagccgg ctaatatcct cagtaagaac cttgatgctt 2563141 ccagcaagac taatcgcttc ttcataatca ccatcacgta atgcctctga cagcatgatt 2563201 gatagctctt ctgctgattc gatttttctt tttgcgatag gaacatctgc cttcaagaaa 2563261 tgattagtat tcatactgaa accgcctgcc ttccttcttg ttttgccata gcaacttgat 2563321 caactagagc tttccgcgtc catctatctg caagttcctg cattttcaac ccgtgagtac 2563381 gaacaagtga ataaatcaat gttttgttag ccgcaatcaa atcaaaaatc tgcttaatat 2563441 cggccatcgg cagctcctct gttttacctg gtcggttatc cgtgagccaa cgggctaaat 2563501 gtttggttgc ttgcagtgct tcctccaatt ggtgaaccat attaatcacc gcattacttg 2563561 cacattcatt gagtgccgga tcaataggag cagcggctgt aggatgaagt ttgaataagt 2563621 aatgtacaag atcaatatgt tcataggcag cgcacttctc aaaccattta atacataact 2563681 ctggagtaag cttggcaagt ccattttcaa catctgaaac atacctttga tccttacctc 2563741 cgattaactt gccgatttgg tattgtgaaa gacctgcagc cttacgggca ctacgcataa 2563801 tctgcggtaa attacgcata ttgtatgggt tgttctccat atgtttgcct cctgttatat 2563861 taggttttta gttttaaaat tgaagttgaa agaccatgct gtttataaat gacttaggct 2563921 gattcctttt tatttttttg cgcaagcttc tcttggtgtt cattcatacg ctgaacaagt 2563981 atgccactga ggtatttgta ggctttggcc tctgcctgtt caaacagtgg tccttttttc 2564041 aagatgactt tcataattaa aaggcctcct ttgtgaattc taatcatgct gaatccttag 2564101 aattatgttt cgtttcgtta catacatcct caaaaaaaat agtccagtca aagcctaatt 2564161 tctctcctat tttttttgag acaataacac taggcttcct agtaccattt tctatcatgg 2564221 tgtagtatgc tctaccaatc tgtgcagctt tggcaacttc ttcttgagta aacccttttt 2564281 ctaagcggtt tttcttaagc cattttctca tcatttttca cccccttaat cagaaaatgt 2564341 aacgtttcgt tacttagata atagtatcga ttcgttacat tgtcaacaca ttttcataaa 2564401 aaaagtatcg ttttgttacc aaaacttata tgtaaccctt tgttacgtta caatgagata 2564461 tagaataaaa acaaaagtca ggtgattaat atgttctccg agaacttgaa aaagtgcaga 2564521 aaacaaaaga aactaaccca acaaaatatg gctgataaac ttggaattac tcggcctgcc 2564581 tacaccgcct atgaactagg tagtcgtgag cctgactata aaaccttaat taatatttca 2564641 aacatacttg atgtttcttt ggattatctt cttaaaggag aaagcaatga aaaagtattt 2564701 caggatgaag caaaaaaagt gttaaacgat cctgaaacat tccttgcagc aaaagacggt 2564761 gaggtaacag atgagatctt acaggctgct ttggagatta taacggagca attaaaagaa 2564821 agacggaaat cagataaata aacgcagtta gtttattatt atttatttct gtttattatg 2564881 tttaattctg tttactaata agatttagat tctcatttat atttcattca taccctcatt 2564941 taaaaagtga ttttgaatcc tttacaaacc cttacgtgac aagggttttt gttgtttttc 2565001 tcatttatat tttcatttat gtttctttta tattctcatg taaaaaaatt gagcgtttat 2565061 tgtgagggaa attgcagagt atcgaaatgg gaaaagaggg cttcttgtta aaaaccttgc 2565121 aaagtgtatg tgaaaaaaat aaacaataca attatcgtaa caacaataat tgtttcttta 2565181 ataaaatttt tattatcttc attcttttgt ttcttttttt taatctcttc tctgtatttt 2565241 ctttgaacct ctttcttctt atcattattt ttcatgatta aactcctttg aagtccattt 2565301 attcccttgc ccctatcatt tgcaattgta ataattcact aatgattaca ccaacaaaaa 2565361 aggatcggca agtgcttttc actcaatggt aaccaacata agcactagct ggacaggttt 2565421 taggatgtat ctaatcgttg aggttccatt tcctgcaact gatccaaaaa cttccttatg 2565481 aagaacaatc tcttctctgt tgtggggatg ctaccaaaaa tagtaggcaa attgatagcg 2565541 gtattaaaaa aacagctcat taaatgccat actggaactg tctttgattt ttggatttat 2565601 tttctgatgc agctattgct atccgttagt ttaattagaa ctcagataat ccaagacacg 2565661 gtcaactctt tcattgactg agcagtcgtc ttcaatcttt aacactggac aagataaatc 2565721 tgccatccaa tgttcatgca aagctctact tctaacttcc attccagcat tatcatataa 2565781 agaagcccac tctaaaaatg tttttgattg ttcatattta ctgccaccgg ctaacacttc 2565841 gtttccataa cgctgaaatt ccctgtgcct tagtctctca agccgtatat cttgtggaat 2565901 ccataagaag acgacaaggt caaaataact ttttagatta tcgccccagc cacacactgc 2565961 accagaaaga atccattttt cattgattgt taagtctttt tcaagcaact ttcttctttc 2566021 aggaatttct ctttttttag tgaatttgtc taaccaatag taattatcag tatcaagatg 2566081 cgtatgaggc aaacgctttg ataatgcagc acccaatgtt gaagttccga caccagaggc 2566141 tcccaatatg tgaatatttt ttttcatact tcccctcctt attaagcaac caaactccct 2566201 gtttgttgca taacgtactt actattattt tgacataaat ccctaaaaga cctttacttt 2566261 tcgagggaaa tccagatgcg tgttaaaatc ataatactta cgaaaacagt catgattaaa 2566321 cggattcata ttccatctcc ttagacgcat tttcctatga aaaaagtctt gatttccata 2566381 taatatttaa acgaatccaa tttttagatt gtcgtcttta aggaggtttt tcatcttgag 2566441 gtatacaaac agtcatttag aggattggat tgaaaactta tacaagaaga ttgatattac 2566501 agaaccagaa caaattaatt ttgaacggat tgccgaggct ttagatatca ggctttcgtt 2566561 taaacctgtt acaagcttcg cacttaaaca cagcggaatt tataatatat gcttggacag 2566621 ccgtaaaagc cgaactgaac aatggtatga ttttgctcat gaattttgcc atatatatag 2566681 acatgaaggc gataaaaaaa caatgcctgc aacttggact gattatttgg attggcagtc 2566741 caattatttt acatatcact tttgcattcc aacttgcatg ttgcgtaata tcaaccttcc 2566801 gtacatacaa tcacatgcaa ttgaaaatgt agcttggtta tttaaggtat ccccttcatt 2566861 cgctaagaaa cgtttaagca tttattacag gaaactgact caacatttat ttagtcaaac 2566921 tgttacggga aatttatgcc cccccttttt gtaatgaata atgaaatcct catgcatttg 2566981 cgcgcattga aaaaaacaaa aaaagacgtc tcccttcacg atccgatcgg gcaggataag 2567041 gaagggaatg aaataagcct gattgacgtt ttgaaatcag aaaacgaaga cgtgatagat 2567101 acgatccagc tcaatatgga gcttgaaaaa gtgaaacaat acattgacat tttagatgac 2567161 cgtgagaagg aagtgattgt cgggcggttt ggacttgatt tgaagaagga aaaaacgcag 2567221 cgagagattg ccaaagaact cggtatctca cgcagctatg tatcgcggat tgaaaagcgg 2567281 gcgctgatga agatgtttca tgagttttat cgggcagaga aggaaaagcg gaagaaggcg 2567341 aaggggaaat aatgcagaag aagccggatc tcatactccg gctttctcta tttgaaagag 2567401 ttatgaaaat catttttttc atcgctgata agctctccga gaaagacagg caggatcgta 2567461 acaaataact tgacttataa tcctcccgca ggcattcaaa gccggacgtt ctaaaagctc 2567521 tcctgagaaa atccttagat cggtatactt cagtacatct ttagtccctg ctttctttat 2567581 acaggcctcg atctggctgt cgatgctcga tcccttgatc gcttgttcca cgatatattg 2567641 ctatcaccct ggatctcctg cctataaagt tttattaaat aatgatagca atcgttcatg 2567701 catttgtcag tttgcagtcc ctcgatgatt attaccttca taaaatacat caccccttgg 2567761 gtaatgctgc gtaatacctg tttgtcctaa tgaggtgatt ttcaatgagt atgaaaacaa 2567821 ataaaaaaac cgatggtttg taccatcgat ctgttttcta tatcactagg ccctcaatat 2567881 agtaaatcta gctcattggt tatgaaagct tattttcatt acacactata tattcatttg 2567941 ttatcatttc tatacgttta tatcaattat ggtaaaaaat ggttacaaaa acccaataaa 2568001 cgtccaacct aactttttca tcttatttat taagaatttt aacctcttcc ttgtgaaata 2568061 aagaagcgat tttcatctcc aaacagttaa tgctatttca tcgggacatg tctgttaaag 2568121 tagccaataa atacattcgg atatccactt acaaccacga ttcaatttga tccactacag 2568181 atttctgagc tgacattaaa cagatagagt tataaaaatc tgtaccagtt ccctttcaca 2568241 attaggacat ttcggcggcg tttcggcata atgcgaacta atttattaat gttcaacaac 2568301 agaatttcgt ctattggcaa taaagaatcc acaaatcatt gcaagaatgg ccatcgccca 2568361 ccagaacgtt gagatcgcct gatcatgatc gatgataatc aaacgaatga cagctgtgat 2568421 gccaatataa atgaagtagc gaagcggaaa atgaaagtct gatttgaagt atttgataat 2568481 caaagcaatg aactcaaagt acatgaagaa tataagcagt tctccaagca tctcataata 2568541 gctgtccact ttgttgaaca gtgacttgta tacgaatagc acaatgtacc aagtctcgct 2568601 gatcagaagt gcgcttaagg ctaacgccag aaagaacaga cagacgttga gaagcgcttg 2568661 taacaggtaa ggcacctttt tgaatttgtt agaaaatctc atcatgttgt ctcctatttc 2568721 aatatattcg tggtttttat tctcagccta catcttggtg ttccaaaatc gtagcacaat 2568781 gtagtactta gaattctttt gtatactgtg aaactgtccc tgcatgcggg acatcattcg 2568841 cgcaatgctt ctttcaccga gtccgttgct ttccggtgtt atatctgcaa gtttaatcgt 2568901 attgctaaca tggatctcaa atatctcttg atccgataca aacgtgatac tgattttttc 2568961 ttccggatct gcgtatttca ataagtttga catcacatta tcaaatacac gaccaagctc 2569021 ctccaaattc acgttaatat aggtttccgg cagctcgcct gaaatatgga cccgaaaatg 2569081 ctcctgatga aggatagcaa tctgatctga tattagatcg tagatcactt ctttcactgc 2569141 aacggtctcc agatcggcct catattcctt gttcagcagg aaatacgcaa acagattgtc 2569201 agacaagctt tttaattgca gtgctttacc ataagcattg gctacatacc gatctttgct 2569261 ggcacccgct tcgcctccct cttttttggc aaactccaga ttcatgatca gcgacgtcag 2569321 cggtgtgcgc atatcgtgcg acatttcggt aaccaggctg cggctctcag cttgcaattc 2569381 ctcgatagct ttaagtttat ccaggaaagc tttccgcaga tcctcaatgc tctttgcaat 2569441 catcgctaat tcatcatgcc cttttatcgt catctcgtag tccagttcgc ccccttcaag 2569501 aatatgaatc tcttgatgaa tcgttttaag gtagcgaaga ctttggcgaa ttccgaagag 2569561 aacaatgatt aaaaagatga gggttgcccc gagcaaatcc aatgcaaagg ccagatcata 2569621 atatcgggaa gagtagaaac cgtcgataat gactcgtcct tcaccatcgc taaacttgac 2569681 aggatgtgaa tgattttgag cgtactgagt cagcttttcc tttccataat ccgattcgga 2569741 ataaatagaa tcatattgca gctcctgatc cttgaatatg gtgaggttaa tgtaattttc 2569801 ttttttgacc cactcgccaa acgcttttct atctgatgta gacaactcat tttctgaaac 2569861 gtacttgctg aatttttgaa tgtatcttgc tgactcctcg tgataatact cttccgaact 2569921 cagatatccc tcgatcagat catctgtgat cttttgcaac gtcagaaaga tcacaccact 2569981 cacaatcgca gcaaccatta tcagcaaagc cagttttttg gttagcgtaa atttaagatg 2570041 cgccaaatcg atatcctctt ccccattcag tttttatata aaccggacgt gccggatcat 2570101 cctcaatttt ggagcgcagc ttccgtatat gcaccatcac cgtattgttg gaacagtaaa 2570161 agtaaggctg tccccacaca ctctcatata tattttgggc agaaaatatt ttgttgcgtt 2570221 tgttcatcag aagtttcagg atacgatact ccagatctga caacttgatt tgcttctcct 2570281 ctttccacac ctcattaaat tcttcgctca ctcttagttt gcccccgata agaaatgttt 2570341 cttcctgttc cttcttttcc tgatagatag tatatctgcg taattgagca atcactctag 2570401 cgtgaagttc ctcttccgag aatggtttag tcatataatc atcgccgccg gcgagtaatc 2570461 cctcagtttt atcgagtgta ctcgatctgg ccgtcagaaa cagaatcggg acgttagagg 2570521 atttcctgat gtgctgacat gtttcaattc ccgaaatgcc tggcatcata atatccaaaa 2570581 taaccaaatc aagcgagtca ttcacaagtt gcaatgctcg ctttccatcc ttggctctta 2570641 gcacctcgta acctgcacgt gtaagggatt cctccaaaag atcaccaata tcctcatcat 2570701 cctctacgac taatattcga taggccatgt ctctctcacc tcatgattct tgttgttatt 2570761 tctcgtgtgt ccttactata tatcgttcat agtaataagt acgttataag atactacgta 2570821 aatcttaaca atttatgaaa gctgatgctc gccacaaatt tgtcacattt tctaaaaaaa 2570881 atgatgactc ttcataaatt gttaagattc ggtctttata tttatccatt gtaaggctca 2570941 agtttttcag atccgcacta cacattgccg tgataaatgg gaaaggagta ttgatatgat 2571001 tgtacaaaaa gaaggacgcg ggcaaccggt gagtctgcgg gaacgggttc attttctgga 2571061 catcgtacga ggatttgcct tgcttggcat tattattgtc aattattttc tgatcgtaga 2571121 ttcagtaaag ggattcgaaa tggcctccga tgacgtactg cataagctgg tttcctggtt 2571181 tgccgaaggg aaattcgtta cgttattctc cttcctgttc ggagtcgggt ttatgatctt 2571241 tatggatcga gccgcgcaga aggtagagag tcccaacaag ctgtttgccc gcaggttatc 2571301 tatcctgttg ggatttggca ttttgcacat cacatttgtt tgggtcggtg acatattggc 2571361 cttttacgcc gtaagtggct tcctgttact cgccttctat aaacgcacgg ccaaaacggt 2571421 gcttagatgg attatcgcac ttatcgtgtt tcaattcctg actcctgttt tcacaatgtt 2571481 gtacaatgtc atcaatactg cagggtcaaa aaacccgaat ttttcagagt ttactttgtt 2571541 tagccacagc agccttacct acatggaatc catcagcact cggtggacag atatggtcac 2571601 gatggctgcc ggctctttct ctatgatcta ttccatgttt ctcatgtttc tgctgggcgt 2571661 gtactttgtt aagatggaat ttttcaaaga catggaagcg aaaaagccta tatggaagcg 2571721 tatctggatc attagcacaa tcgcttttct aataacacaa agcagtatat tactagacat 2571781 gtttaatctt tctgagaata tgctgtggaa ggacatttcc tctgtcttgg gtcaaaatgg 2571841 cggcttaacc ggaagtatgt tttatatgag cacttttgca atgctgtttc tataccttcc 2571901 tcagctgcga ggccctatga tgatattcac caaagtcgga cggatgtcat tgacctgtta 2571961 tctgcttcac tctatcattg gaacagttct gttcctcagg tacggattcg ggcttgcgga 2572021 tcatattcaa tccgccggca cgttcatgtt cagtctggcc gtgtacttcg ttcttatgag 2572081 ctttagtaca ttgtggttga aacggtttag gtacggtccg atggaattag tatggcgcaa 2572141 gctgacgtac ggcaaagtaa acgggagtcc caaagcaact ccgctgcatt cggaaaaatc 2572201 tattcagaaa taaccccctt gcacagattg catgacttca aattagtgtt gttgaatgaa 2572261 gcgggcatta aacggacaga tttgatatat ggactagtta tttttatatc atttaggctt 2572321 ctttgggcta ataaatccac cagagtttac tcaatgtgca ttgctcatga tcgaatctaa 2572381 attgaatctt ttacgcatgt tcatagtcaa aggcgcctca ttcgactatt tttgtaactt 2572441 ttcgcaggaa aaattcgaga atgatgacaa atcccgcata cgacacttaa tacggtagtg 2572501 aacaatagta aattagggtt acatgcagct tgttttccaa tgaaacaaag aaaaagaatc 2572561 atacaaaaag acaggagaaa gcttttgaag tattttaacg ccaaatttac cgcggaagaa 2572621 agagcgatgg aatcactttt ttgtgaaaag gcctcgcaga gcagctcgaa tgttttactg 2572681 aacgactgaa ctctatattt tagcaactga gggagtgaac aatcatgaaa actaaaaatg 2572741 aaccaaaagt tattctggaa ctagcaaagg aatctgatct gccagaattc caaaaaaaat 2572801 tacaagaagc ctttgcgatc gccgtgattg aaacgttcgg tgattgcgaa gatgggccga 2572861 ttccatcgga caatgatgtt caggagtctt tcaatgctcc cggagcagtg gtatatcata 2572921 ttcttcagga tggtaagaat gtcggtggtg cagtagtacg tatcaacagc caaacaaatc 2572981 ataattcgct agatttattc tatgtatctc cagaatatca cagccaaggg attggtcttt 2573041 ctgcttggaa agccattgaa gcacagtatc cggatactgt gctttgggaa accgtgacac 2573101 cttatttcga aaagcgaaat atcaacttct atgtgaataa gtgtggattt catatcgtag 2573161 agttctacaa tgaacatcac tctaatccgc atatgcatcg caatggacgt gaagatgaca 2573221 agcccctact gaatgatgat gactttttca gatttgtaaa gattatgaaa aaaaaggact 2573281 aaacaattga acacggcgag atgccgcaga gagttgctgg taactttttt atatttcatt 2573341 atcagaggaa ggtaataatg atgtttaaaa ggtgttttga tccctgtctc ataaacaggg 2573401 gtcaaaacac ctttgaatca tcggtttctt ttctgacata taccacgccc actagtccct 2573461 caacatagta aaaacatatc atgagttaca aaagctttta ttcaaagcat atgtttattt 2573521 tatttatact tattttcatc atttttcaga attctggaca caaatcgggt acctattaga 2573581 ggccaaggaa ctctacattt cattaagaaa tacgtactca ttgccctgct ttaattaatt 2573641 ttaagccctc gcactatgcc cccccctgaa ttaagtattt gatgtaactt tgaaattaag 2573701 tttatgaaaa tctgtcacaa acccttattt cataacacat catttgtttc agcttccctc 2573761 gcgaataccg gattaatgct cggctttaag atagtcaacc aatctctccg cactgttctt 2573821 aacatcttct tttgaaagat gaagtgtccc atattgtgta aacgcaggaa gaaaacgcat 2573881 tcctatatag ttagcagtga cttgaaacgg tctgataagc tcgctgatcg tgatattata 2573941 ttctccgcct gcttgataat cagattcctg tgcgcctaag gagatagcta agagtagttc 2574001 ttttccatgc aatttagttc ctccagttcc ataagcccag ccatgtgtta acacatcatc 2574061 ttcccattgt ttgagtaacg cgggactgct gtaccaatac attgggaact gaaaaacgat 2574121 acgctcatga tctaacagga gctgctgctc tttttctaca tcaatgataa aattagggta 2574181 ttcaccgtac aggtcatgaa ccgtaatgtc tttctcttgc tttaaacgat tcatccaggt 2574241 tttgttgaca acagacgttt ccaaattagg atgtataacg ataactaatg ttttcattag 2574301 actgattatc ctttctttgc caattagtta ttatttttta cgataatgaa ttgattctaa 2574361 ttttaaaata gcaactttat ttacacctat tttatccttt ttcatgaatt cagggcaact 2574421 aattgggcac caaaatcaat gatgacttaa gacattgttt tgtagaaatc cgatatacag 2574481 aataatccat tatttagaaa atttctacct tttccctcaa tccttaccaa tttaaactca 2574541 ttaaggagat actttatcac caactttaaa taataatgga ataagtgcta ataaaataat 2574601 tcctacaacc aacgtagata ttattaactc cttccataca atcaaattct ttaaaaacat 2574661 ttgataaata actaatgagt ttactggaat gttaagcaat aagcccgtaa gaagtccagg 2574721 tgcatacttt ttcattacaa cagttgcgat aagatgtgga aaaatagcgt tgataaccat 2574781 agaacctaga aagccaatga aaatccattt tgcaatatct gattctggca tatataaaaa 2574841 accaaatgca gataaataag ccaacatagt tataacaatg acagcaaaat gaaattcatt 2574901 tgaagttact ggcttttgaa actttgaaga ttgttgtgac cactcaggta accaaatagc 2574961 ttcctcaata ttatgaagtg taatagcaaa acaaaaaaat gctacgaaat aaaccaccta 2575021 tcatttcctc ctcggtgcca caaccaatat ggtttggcaa cattatatta catttgaggc 2575081 tgattggata tggtgttaaa agagagaaga atctgcctta gtagttgctt cttaattata 2575141 tgtgcaataa cgtgttgtta cgtggcatgt catattcaaa tataataact ctaaagcaaa 2575201 caaagatacc tatatagttt ggcatcctct tttttagttc gagtccctct atttattttg 2575261 ggcacaaaat agacataatt tatattgact cattataccc atcacatacc atacccctta 2575321 aaccaatcag gattaaaatg ttttaaaaaa ggtgatcaaa gattaagtta tggtctcttt 2575381 tattttatgt atgctgtctt aatgcaaaac aacactggac accactaagt caaatgcatt 2575441 tcatggtact atagtcaaga cttgtccaag tcaccattat caaaatgaat ttcatcaaac 2575501 acttgaaaca tttattgaac gcggccaagt gtcataacat taataagaaa ccaacgagtg 2575561 atgaatcttt taatctttca ttttacccgc tggctcatat caaaggagct ctaaccaaat 2575621 tttaatagct gtcgcaccta ttaattgcgc taaaacccat tgcaggaatt ttgtatttac 2575681 tttttgccca actgatgcgc caataggaga agctattaaa ctagtaatca taagaaccag 2575741 agctggtaca aaaagaacct ggcccgtgat tacttttcca actgttgcgc caatggatga 2575801 aagaaatgta atcgcaagag atgaagcgac tgtgactcta acaggaatat ttaaaatcga 2575861 taacataatg gggactagga taaaggcgcc gccagctcct aaaatacctg atacgccacc 2575921 aatgataaac gctaaggaag aagccaacca tttattaaat atcacttcct tatcttcgct 2575981 atgttcttgt cctttctgtc cttttttagg tataaacatt aaaataactg ctataatagc 2576041 cagaattccg tatataaagt taattccttt ttcagatata taatgagaaa agtaactccc 2576101 caatacactc cctaaaagga tgctgcttcc catgtaaata attaatgttt tatttataag 2576161 accactctta cgataagccc aaacaccgcc gagtgtcgca aaaaaaactt gaatagcccc 2576221 tatccctgaa acttcatggg cagttaatga catcactccc actaaagaag gaatgtacaa 2576281 tagcattgga taattaataa ctgctccgcc aataccaatc attccggaaa taaaggcacc 2576341 aataaaccct ataatgaaaa gagttgtgat aaaggcaata tccattttat ttgcctcctt 2576401 tcataggaaa agggtatctt tctattcgat accctttcac attcattagc ctttttgaat 2576461 ccaaaatttc aatatatcgc cctcgtccgt ttgctctaaa aggtcatgtc cgcctgattt 2576521 agaccaggct gtaagatcat ttttggctcc cttatctgtt gcatgcactt ctaatatttg 2576581 acctgattcc agttcattca tcgctttttt tgttctgaca attggcattg ggcatgccaa 2576641 gccttttgcg tctaatactt tatctgattt catgttcttc tctcctcttt ttagcagaaa 2576701 cttgtgttac cgtattgcac agcggtttgg gccaatctcc atttcacgct gtttttcttc 2576761 atctgggctg attttcccca tgtttgtttc tcgaatctct tggtatgcat ttggttgcgg 2576821 aggcaaatga tctgttacta ggtgtctaaa ttctgtttca tccgcaatgt tcaaaccatg 2576881 gttctcgcta aataatgtac ttagttgttt accaacactt ccattctcat ttagctcgtc 2576941 aatgatcata aagtgtgccg gtaatacaat taaatccttt gataacgctt tgtaacggct 2577001 ataaagcgtt tttcttaaat ctcctaccca atcttctgcc ataccggcta agtctggtct 2577061 gccgattgaa tcaataaaca agatatcacc tgaaagaaga tactggtcat cgacaatgaa 2577121 agaagtggag ccaatcgtgt gccccggaga ataaatcggt tgaattttaa tcgttgtatt 2577181 tccaataata atgtcatttc cttcttccaa cggctgataa tcgaattcca cttcttcagc 2577241 atctttaggc ggtaaccagt aggttgcttt tgttttttca gcaatgactc tgccgcctga 2577301 aatatggtcc gcgtgaagat gtgtatcaaa tacgtgagta atcgttgcac ccttcccctt 2577361 cgcaaaatct ataaagaaat tcaccatacg tgtcgcatca ataattgctg cttcaccatt 2577421 ggaaatgacc atgtatgaca agcagccttt accgattcga acaaactgat acatctcacc 2577481 gccatctttt aaatccccga cttttaccgg ctctaaatgt tcgctccatg ctttcattcc 2577541 acccttaagg taggatacag aatgacctgc ttcagaaagc atttcggata ccatgacgga 2577601 tgaaccttct tttgcgcaaa cgaccagcac ttctttatca gaaggaattt tctccaagat 2577661 atcttctacg ccatctaaaa gatcaaaata aggaacattc aaatggtcaa agtcatgccc 2577721 ttctatcttc caatcactaa aatcattttc attacgcaca tccaaaataa ataaaggttc 2577781 tttgttaaag atttttttgt cacttctttt ggggtcattg cctttacggt catgtttcaa 2577841 tacctcctat atcaaatctt ttagcgggac taaaacgtta aggatacatc agcatctttc 2577901 gtaaaaccaa aaaaggtaac agccccgcct acttcgattc cttccataaa atcatctttt 2577961 gttaaaccca taacgtccat cgttatttga caaccaaatc atgcaactcc catttcaatc 2578021 agttaagaat agaaggcaca tttgcgttcc tacaaccttc tgcgacatgc tcttttcctt 2578081 gtcgcaatat tacagacttt ataagcatca aacagaccgc tatttgccgc aataatcgct 2578141 actcttgtac tcatctgttc atcatgcttt ttatttattc ggttttacct gtccaatccc 2578201 gcatacccgg gacaacatta ataacctttt taaaaccttg ttttttcatg gtgcgggccg 2578261 ccatttcact ccttcttccc gaatggcaga taatataaat ttcatcattt tcgtttaatt 2578321 cgttagcgcg cttttccact tcaccaagag ggatatgcac aactcctggg atatgagctt 2578381 tttcatattc ctctatctct cgaacatcta aaatgttaag agactcgtca ctatctactt 2578441 tctgtttgaa agcttctaat gaaatctcag gaattgaaga tgcattttct gatgaatgct 2578501 ctcctccttt tcgaagaaaa tgacgaagta tttctccctc tgcttcagta cccagatatt 2578561 catggcctgt actttttgcc catgcttcca gatctgctgt agaaccttta tctgtcgcat 2578621 gaatttccaa tacttcacca gcttttaaat ccttcattct cttcttcgtt tttacgatag 2578681 gcattggaca cgccaaacct ttagcgtcta gtacaatagt tgctttcatc attttttcct 2578741 ccttttctta tataggggtg ggggtataca aatatacaaa aagtttctca ctgtaagtta 2578801 acaccatgta ttcatacccc cttttatatt tgtgatgttt ttaaatcctt gtttcttcaa 2578861 tatttttact tgcctttaaa cttctcattc cgcttagcaa tgagtaaatg agtaacatta 2578921 gataaataag ttgacactgc cttcctcagc atctgccaaa taagctgcta caccagcata 2578981 gtcaatatca tctaatagtt ctttttcctg taaaccaaga agatccattg tcatcgtaca 2579041 agctacgagc tttaccccct gttcttgagc catctcaatc aactgaggta aagtaagtac 2579101 attatgcttt ttcatcacat ttttaatcat tttagggccc atacctgcaa agttcatttt 2579161 agataaaccc atcttatcag caccacgagg catcatcttt ccaaacattt tttcaagaaa 2579221 tccttttttc actggaatca gctcttcttt acgtaaagcg ttaaatcccc aaaaagtatg 2579281 gaagatcgtc acttcatgat cgtaggcagc tgcaccattt gcaataatat aggctgccat 2579341 tgctttatca taatccccgc taaataaaac aattgttgtg cgttttgttt gttctgtcat 2579401 gtttattctc ctaactaatt acccctgcgg gtatattaaa gtcaaaaaat tttttcgaaa 2579461 gatctgcttt tattcaactc tttaaatacc atagggggta taatataacg catataaaaa 2579521 ttcgtcaacc ttaggttgat gaatttttat cggctcttta ccaataagtc gactgcttct 2579581 tttactaaat tttgtgtgtc ttcgcctttt tctaaacttt cacgaacaca atgttcaagg 2579641 tttgtgctca caattaaacc catcgctcga tcgatcgcat tacgggaagc tgctaattgg 2579701 gtcacaacct ctctacaatc ttttccttgt tccatcatag tcaatacacc tttaatttgt 2579761 ccttcaatcc gtcgtaagcg gtttttaatc ttttgatcat actccatata tcaatgaaat 2579821 cctttctttc atttattttt acatttacat gttgccagtt cataactgtt tacatggata 2579881 cctttgcgct ttagaaaacg cactcctaaa tttaattcca cccggtcacg agctattatg 2579941 tgtattttat cacgtggaat ctctaaataa aaacgtttta gatacgcata tgggatgttt 2580001 aaaataatat tatccgaaaa attggctaca tcgttataat gacgaatatc taatattgtg 2580061 atgtccatag cctctaattt atctttatgg atacaagaga ttccggttat aggataataa 2580121 cgtctatacg ttgcaatgat aatcacaaaa ataagcagga atgcaataac taaataattg 2580181 atactattta caccacctta ttaactcttt gtttattcac aaaacaataa tataccccca 2580241 taggtatata gtcaagtgtg aaagttactt tctttgagct gatagattca tttcgatatc 2580301 cgcggattga aaaaatactt acattcgata atgccaattc tgctaaaagg aactcgaata 2580361 aagcaataag ccgatttaat tttaaatcgg ctttatttat caattactta aaattagcac 2580421 aagacacgct gcttggatat taaatggggt ttcattagca tggtactggt tccccatgtt 2580481 tcatgctgga tgtgacttta attattctag aattctccag aatatctgtg ctaatcttcc 2580541 gcagccactg catctgcttt ggtttcatga actgtaccaa atggatggtt aggaggagca 2580601 taaatggagt aaagttttaa tggcgtattt cctgtattaa ttacgttgtg ccaagtgccg 2580661 gcagggacaa caatggcaga atcatcatag acatttcttt gaaagttcaa atgatctttg 2580721 ctctttccca ttttgacgat cccacgcccc tgctcaatcc gtaagaactg gtcaacgtta 2580781 ggatggattt ccaaaccaat gtcttctcca ataccaagac tcatcaaagt aacttgaaaa 2580841 tgctttcctg tccataaagc agtacggaac gtattgtttt gttttgtggc tctattgata 2580901 tttacaacaa atggttttgg tccataatcc ttcaaaagaa ggtttctatc ttcatatgaa 2580961 gagcgcaaat cggcacctct gtgtactttc tccatctcat ttggaatagt ccaataaaca 2581021 gatcttccat cattatacat cggcacagtc acataataat aacattgagg cgaaaaaggg 2581081 ttatagtaca ttttttgatc cccgcaatta taaatttttg tgatagtatc ctatgcattt 2581141 attaagggag tgtgctaaat caagaaaact catattaaac acaaaaatga atgttcgatc 2581201 accgtttgat tcatggatga ataatttatc accgaccttg taatcgtttt ctagatgttg 2581261 aatttcacta gcctttgtta acaagacatc gaatgacacc tttatatgat ggattatcaa 2581321 aggtcgacga tcctaaatgg cttttgaaca tttacatagc acaacaacag agtatacgga 2581381 attctgttgt ttgtcccccc tatcccagct cttttagatt tatctctttg gatgcgcctt 2581441 gatggccagt ttttcagcag catagaattt atcccctcct gaatcgttat agcatatttc 2581501 aacgccgata gacttgcggt tcccagtgcc gtttgtaccg tctcctgtat gtgggctcgc 2581561 ttttagtaaa ccagtttata ttctttttgg gcacacaaca gaaacaattt tccatatgaa 2581621 aatctcgtaa ttttacacct ctttaacttg aaggaggatt tttgcatatg tattttcata 2581681 cccgtcaact accatctcat ccagcatata ttcctcatat gcattttccc ctatttgcat 2581741 tccatttctt tcaatgaact caatgattct ccggtacgcc tcttcagtat ttccgcctat 2581801 ttcatatcca actgcataca ggccttttgg ccgtacatga taatttatgt tctctgcccc 2581861 atcttttact tttatataaa agtaactgta attgtagaag tctttttcta agatttgttc 2581921 ccgtgcaaag attccgccta tcggatatcc ttcatctaat tcatattgct gaacttcatg 2581981 aatgagttct gaaatggctg ccacatattt tcgttctggt aagtttaatg tttttcggct 2582041 taacatgaat gtttcttcat ttaaatattc aaaagaaatt gaggaaaaat cagtctcaag 2582101 tgcttgttct gtaagcgtca cttttgtttg taagatcgtt tgcaactgct taagctcatt 2582161 tattttttta tcaatctcaa tagacttttc ttttagaaca tgcaggatct tgtctggtgt 2582221 ttttcctttt attagacact ttatttcttt taatggaacc ccaagctctt taaatagact 2582281 gatgacttga aaagtctcaa attgatgata ggaataatat ctatacccat tttctttttt 2582341 tatttccggc gagaaaagac caatctcatc ataatgaaat aaagtttgtt tttttacacg 2582401 gcagagcttc gaaaactccc ctgttgtgaa atacttctta acatcttcgc tcataaaaac 2582461 ctccttgact atacggtaac catatacctt atgatttgat tgtacttgaa aaaagcttca 2582521 agcgaaaagg ataggtaaaa agggttcaat tgagtaaaag gggaattcag atgaaaaaat 2582581 caataaatga gcaaaaaacg atattcatta tactattaag caacatcttc gtagcatttc 2582641 ttggtatcgg tttaatcatt ccagttatgc cttcttttat gaaaatcatg catttatccg 2582701 gcagcacaat gggttatctt gttgcggctt ttgccatttc tcagttaatt acttcacctt 2582761 ttgcaggtag gtgggttgac cgtttcggga gaaaaaaaat gattattctc gggttgctta 2582821 tattcagttt atctgagttg attttcggat tagggaccca tgtttcaata ttttatttct 2582881 cgaggatatt gggtggtgta agtgcggctt ttatcatgcc cgcggtaaca gcatatgtag 2582941 ctgatattac aaccctaaag gaaaggtcaa aggctatggg gtatgtttct gctgcaatta 2583001 gcaccggctt tattattgga cctggtgcgg gaggatttat tgccggcttt ggtatccgca 2583061 tgccgttttt cttcgcctcc gccatcgcgt taatagcagc tgtcacttcc gtttttatac 2583121 taaaagagtc attgtcgata gaagaacgcc atcaactctc atctcataca aaggaatcaa 2583181 atttcattaa agacttgaag agatccattc atcctgtcta tttcattgca tttattatcg 2583241 tctttgtaat ggcttttggt ttatcagctt atgaaacggt attcagcttg ttttctgatc 2583301 ataaatttgg cttcacacca aaagatattg cagccattat tacgattagt tccattgttg 2583361 cggtagttat tcaagtttta ctattcggga aattggtcaa caaacttgga gagaaaagaa 2583421 tgattcagct gtgcttaata accggtgcga tcttggcttt cgtgtctact gttatgtcag 2583481 gatttttaac tgttttgctt gtaacttgtt ttatttttct ggcgttcgat ttgctacgtc 2583541 cggccttaac cgctcattta tccaatatgg ccggtaacca gcagggtttc gtagcaggca 2583601 tgaactccac atacaccagc ctgggaaata tatttggacc tgctctaggc ggtatactat 2583661 ttgatcttaa cattcattat cctttccttt ttgcaggttt cgttatgatt gtcggccttg 2583721 gtcttacaat ggtttggaaa gaaaaaaaga atgatgctgc agctttgaat taattcattt 2583781 tctataaagt taagtcattt ggatgcaggg aatgcccctg gttaggcaca ataagaaaag 2583841 gtacttaatt tgataggcta catgttgctt gacgtgaata tagtataagc tgagttttag 2583901 caatatcagg ataccgggat aagaaaaaag gagaatgtag tatgagtata aacataaaag 2583961 cagtaactga tgataatcgt gctgcaattc ttgatctaca tgtcagccag aatcaattat 2584021 catatattga atctacaaaa gtatgtttag aagatgcaaa agaatgtcac tattataaac 2584081 ctgtcgggct ttactatgaa ggagatctag tcggttttgc aatgtatgga ttgtttcccg 2584141 agtatgatga agataataaa aacggacgag tctggcttga ccgatttttt attgacgaac 2584201 gctatcaggg aaaaggatta gggaagaaaa tgcttaaagc cctcattcag caccttgctg 2584261 agttatataa atgcaagaga atttatttaa gtatatttga aaataatatt catgctatac 2584321 gcctttatca aaggtttggt tttcaattta atggtgaact cgactttaat ggtgagaagg 2584381 taatggtaaa agagctatag atatccaagc ctccttgttt gctgagaaac gtttgaactt 2584441 cgataatgat tacctactta aactgcaaga tcattgttta aaaaagcctg gatgaaaatt 2584501 tcatctcagg ctttaagcat cttattagtc aaaatctcat gtgttttatc cagatgttat 2584561 tcttttttcc ggacaatttc taaataatta atatgccggc caactgtttc gtgcacttta 2584621 aaaatatacc catcggcttc tataacggac ccaactgcag cgtctatttg ttgagtcata 2584681 aaccagccgc ctattgtatc cacttcgtca cttgctaacg tcgttcccaa taaatcattt 2584741 acatcttcaa tgagcacttt cgaatctaag atatagtgat tatcatttac ttttctaata 2584801 ttaggcactt catctttatc aaattcatct ctgatttccc cgacaatttc ttcaagaata 2584861 tcttcagcag tgactaaacc tgaagtgccg ccatattcat ccacaagaat agcgatatgt 2584921 gttcgctctt tttgcatttt taccaataca tcatgaattg gaacggattc aataacatgg 2584981 ataacagggt tgatatgatt ttctaacttg aaatcctctt ttatcttctg gtctgtgtca 2585041 atataagctg acaaaaattc tttagcattg ataaaaccaa tgattgaatc tttatctcca 2585101 tttaggactg ggtaccttgt atagctctct gtcttaatga tcttaacaat agtttcataa 2585161 gaatcctcac tagaaatcgc tacgatctct cttctcggaa tcataatttc tttggcgatt 2585221 ctttcatcaa attcaaaaat attatttaca tatttcaact cattttgatt gatttcaccg 2585281 ctcttatagc tttcagacag taagatgcgc agttcttctt cagaatgagc aagttcatgt 2585341 tctgatgcag gtttcaaacc gaagagtcct actataaacc gggctgaacc atttaaaaac 2585401 catataaaag ggaacaggat gcggtaaaac caaataattg gctttgcagt caaaagagtg 2585461 atggtttccg ctttttggat agcgagtgtt ttaggagcaa gctctccaac tacaacgtgc 2585521 aaaaaagtcg ccatcacaaa agcaatcact aagatcaata catgtgagac tgtttcactt 2585581 acatgaaaat gagcaaataa ggggtgcaaa atcacttcaa aagtcgattc tccgacccag 2585641 ccaattccca acgctgtaac cgtgatccct aattgacaag ctgacaaata ttcgtccaaa 2585701 tgagtaatga cctttttggc tgatatggca cctttttttc cctctaatat gagttggtca 2585761 atttttgatg acctgatctt tactatcgca aattcagtcg caacaaaaaa tgctgttaag 2585821 acaattaaaa gagtaaagat tataaggtta atggttgtca atgatttgcc ttacctagta 2585881 aggcgtacac ctccgatgta aatatttatt gaataaacaa aaaacagtat atataacatt 2585941 ataagttcaa aagaacctaa aatcaactct gaatgatgta aataatcatc tttttccgta 2586001 tggagagtgg ttcccatagt cttcaactaa cgattagtgg cgttttaagg cttaaaaaag 2586061 aaagcaaaat aaaaacacac ctgaattttc tggtgtgttt caataatacc caaccgtctt 2586121 gatttattta atgtctttat aaagattttc ttttaaaatt tgaatcaatt cggcctgttg 2586181 ctttatattt ttgcggccat ttctattaat tgcagcaagt tcacagacaa ttccagctga 2586241 aatgaaaaac aataaacctt caaacatttt aaatccccca ctgtctaagt gatagtcaaa 2586301 tttgtttttt ctttttgcaa tacctgctta taatcttcct tacgctgata tatgttattt 2586361 aaaatgagtc caataatgac aaacagtgtt cctactatat caaaagcagt tatgttatat 2586421 cctttgatca ccatgattaa caatgtagta atggggacaa agttaataaa taaaatccca 2586481 ttaatggatg ataggatttt aatgccatag ttccaactaa ggagggctat gatacctggt 2586541 aaagtaatca taaataaaaa atcatactta attgctgcaa tcactttaat actcggtacc 2586601 gacacgtaac cttgcgcggt aagtatagct gtcatgattc ctgttatagc tgtgccgaat 2586661 aaacatgtca aagttgaata acgaagtgtg gaccactctc ggaatatctg tccccccatt 2586721 gtgtagacaa cccaccctaa aacaccaatg aatataaaga gtatcgagaa tagatgatcc 2586781 cctaatgaaa aaaagaaact tatattacct ttggttatga ccatcgaagc ccccaaaaag 2586841 gcaatcaata tactgatcat tgtgtatttt ttaggtttca catgtttata tccccataga 2586901 ataacaattg aaagcatcgg catgagtgcc tcggcaatgg atgctgtcat aattccagac 2586961 ttccccatca acctttgacc taaaaaaata agaacattgt atatagtaaa cgccatcacc 2587021 ccaaataaaa tgatccattt tgctttaccc tctaaatgaa atgatttctt tccttctctc 2587081 accaataata aaatcactaa cataatcgtt accacaccgt agcgaataaa tgaaaaataa 2587141 aacggatcaa caaattctaa tgcatgatct gcaactggaa acatcgcgcc ccaagacata 2587201 cttgctacta aacatgtaag ggcaccaatg aataattgac cttttttcat tgaattcccc 2587261 tccttttctt taaaattaca atgagaatta taaaaagaag taagcatcaa gtaaaatgaa 2587321 caaaagtgat gaaaaacatc attgataatg atactttaat gaagggggga tcttcatgga 2587381 actgcgagac ttacaaattt tcaaatgcgt agcccatcac aagagtatta ccggtgctgc 2587441 aaaagagtta aattatgtac aatctaatgt aactgcgcgg attaagcaat tagagaatga 2587501 gctcaaaaca cctcttttca atcgccataa aaaaggggtt tcactaagcc cagagggccg 2587561 aaaaatgatt gaatacgtta acaaaatttt gaaagatgtt gaagaactgg agcaagtctt 2587621 tctagatact gaaataccgt ctggaatatt aaaaatcggt acagtggaaa cagtgaggat 2587681 actgccgacc atcatagctt cctattataa aaagtatcct aatgtggatt tatcattgca 2587741 ggctggtcta acagaggaac ttattaaaaa ggtcatgaat cacgaattag acggagcttt 2587801 tatttcaggc cccttgaaac attctattct ggaacagtat gatgtttata ctgaaaaact 2587861 tactcttgta accagtaaca aaacgtttaa tatagaggat ttttcaacga ctccgattct 2587921 tgtttttaac caggggtgcg ggtatcggtc taggcttgaa caatggctca aagatgaagg 2587981 tgtgctccca aacagaatga tggaatttaa catcctagag acaatcttaa atagtgttgc 2588041 acttggactc ggtataacag tggtaccgga atctgctgtt atgcatctag ctgtacaagg 2588101 taaggtttat tgccacccat tgcctgagaa agacagctgt atctcaacaa tttttatacg 2588161 ccataaagat gcgtacctga caaattcaat gcgcagcctc ctaaagacca ttgttgaaca 2588221 taaaaatatg agtatggctt aaagtgattt ttctctttct atattctaac ttcttaaata 2588281 aaagagaagg ctcatctcca cttcgctacc cttattcacg caaaaaatag agcagtaaac 2588341 atgtgagtta ctgctctgct tcgtttattc accgttcatt tgttttacaa tgtattcagc 2588401 atcatttcct acgccttgaa gcaacgctga acctcgctta tgctgccaag gcaaacctat 2588461 aaagtacaat ccttctacag gtgaaacacc tctatgatgt atgattcgac cttcttgatc 2588521 caaaacacct tttatattta tccaacataa gggattcctg aaaccagtag cccaaataat 2588581 attgtttact tctaatgtag atgaatcttt aaaaatgatt tcattttgct ttgcggcaat 2588641 gactcttttt tttaagatga tctccttctg ttttattgca tgttttaatt catgcccaaa 2588701 tactggatca cctttctttt gaatgaattt gcctactatt gatgtatgac ttgcatgtaa 2588761 aactcctagt ttatcaaacc accaaaagat gcttcttttt ccgatcatta aagggaaata 2588821 aacaagttta ttactacaag ctaaatatgt aactctttct ttggataatt caacagctat 2588881 ttgagcacca ctattcccac caccaactac tagtacattt ccatatgcca attgttttga 2588941 attcttatat tgtgatgagt gtagttgatt aatattatcg gataaatcct ttgatattga 2589001 tggaatatta ggggtatgaa aaggccctgt agcaatgaca agattcttcg tttgatattc 2589061 ttcccgattt gtttttatta agaaataatt ctttattttt aggacactta ttacttctgt 2589121 ccgtaattgg attggaattt caaatttttt aacatacttc tttagataag caacaatttc 2589181 attttttgaa ggaaatccat gtttttctcc ttcaagatgc attccaggca aagagctata 2589241 cattcgagaa gtaaataaaa ctaatgagtc ataccgatct ttccagctct cccccacctc 2589301 atgactttta tccaaaatga taaacttttg atcggactgc ttaagataat atcctattga 2589361 gatccctgct tgaccagccc cgattactat agtgtcgtac acattatcac cccgccaatt 2589421 tcaaattgtc agtagacaga atctgcaaaa tcctagttga tctcctcact ataaagttag 2589481 ataaaaaatt taatggtgat ggtggtcacg ctgcttctcc attttgggct gacaaaggat 2589541 cgcattgtcg tggttatgcg cttcggtttc catttgaatg gttacgtgcg taatgccttt 2589601 atgctcaagt tcatgttcaa ttttgcgtaa aatattttca ctttctgaaa tggtcagttg 2589661 atcgtcaaca actgcgtggc aagaaagagc attcaatccg cttgtgatag accatatgtg 2589721 taaatcatga atgttttgaa ttccctctgt cccttcaatt gtacgaatga tatcagagac 2589781 atcgatattt tctggagttc cttccattaa gatgtgaatg gaatctttag tcacattgta 2589841 accgcttctt agaacaagaa tagccacaat gatactagcc aatggatctg cccagcccca 2589901 tccaaagaag atgataagta tggcagctaa aatggcacct acagagccga gcatatcgct 2589961 tattacatgt aaataagctc ctcttatatt cagattattc tttgtatctc cgccactcat 2590021 cataatccaa gcgaccaata gattcacaac taacccgatg atactaattg taagcatgcc 2590081 ggttgttgct acttttggtg gattagagaa gcgttcgatt gcttcataaa tgatataaag 2590141 agaaataaga attaaggcag caccgtttat cacagctgca agaatctcaa atcgtttata 2590201 gccgaatgtc ttattgtgat ttgccttttt ttcagctaat gtaaaagcaa tcagggcaac 2590261 cattaatgaa attgaatcac tcagcatatg gcctgcatca gataaaagcg ccaggctatt 2590321 tgttaaaaat ccacctatag cttctataat catataacct gtaatcatga taaaagagat 2590381 caataaaacc tttttatttg ctccttcatt atgattgtga cccataaaaa actcctcctt 2590441 acctaaagtt tttaatacat atgtatttat tatttcaaat ctgttatgaa gcattctaac 2590501 atgatacaaa taatatttat atatgagcat gtgttcatat ataaatatat ctgctcttta 2590561 ctgaaatgtc aaaatatttt tatagaaatc cacaatacct ccttaattat tcttttataa 2590621 acataaaaaa gcggagcaaa cacatggttt gctccgctac cctagtttct ctatcctttt 2590681 cttcaatcaa gcatttgagg gtagtattca actacaattt acctgttaaa aattgggcct 2590741 caccaagtcc aaaactccag tcagcattat cattttcaac aatagataca attaaatcag 2590801 ttgatgcgat accacactca gattccagtc tttcagctaa cagcctgtaa aatttttgtt 2590861 tcttctcttc cggtcgggat ttacttgtaa ctgaaagaac aacaagattt ttagttcggt 2590921 taaatcctaa cccagtatcc tcaataatca tatgattttc tggatgttca tgaacaattt 2590981 gataacggtc ttgttgaggc acatcaaaag cctctactac aacattgtga gcgacatcta 2591041 aaagtttttt caaacttgat tgatctcgcc cttctattaa gtcaaaacga agtaatggca 2591101 taaaatcccc tccttctact acaacagtct ttttaatttc attcgttaat gtgtcagcta 2591161 tttccaagca gctgctacat ttagaaaata aagtaatttc ccaataaccc cttcattctg 2591221 gtgttagtca agcctatgtt atgatgtgta tttccatagg caatatacag aatcaacttc 2591281 gagtaattaa ccattttttg aaatagcttt atcacttact ttagaaatca tttattcttc 2591341 taagctttag tttacatgaa gctctgctat catatataat tcaaaattaa gatggaagac 2591401 atctcaaaat cagatatcaa ctatggagga ctagatgaat attcagttgt tacaggtttt 2591461 tctcactact gctcgtgaag gcagtatttc caaggctgct ctgactttaa attatgcaca 2591521 atcgaatgta acgaataaga tacaacaact agaaaacgat ttacagacaa aattattcta 2591581 tcgtcatagt cgaggaatca cacttactcc cccagggcaa attcttgttt cttactcaga 2591641 gaaaattcta catactattg aagaagctag agcagccatg ggcgaatcat ccgcgccttc 2591701 tgggccactg cgtataggat caatggaaac aacagctgca gtttggcttc ctcaactcct 2591761 tgcacattat aataacctct atccaaatgt tgatttgaac ctagtaaccg gccctacgga 2591821 acaacaaata caagcagttt tacattatga gttaaacggc gcttttattt cagggcctat 2591881 tgaacaccct gatttagttc aagaaaaggt attggatgaa gagatggttc ttgttacaag 2591941 tgcttcacac cctgtgattt cttccattca ggatgttcaa acacaaacaa tgcttgtatt 2592001 ccgtaaagga tgctcataca gagcaaagct caatcatatc ctgcaagaag aaggtttatt 2592061 acctataaaa ttaatggaat ttggcatact tgaagcgatc attggctgtg taagcgccgg 2592121 cttggggatt tcactgctgc ctcgttcaat cattgcttcg catgaaaaag aaggccgcat 2592181 ccgcagccac actatctctg acaaatattc ttttgtatca actatgttta taaggcggaa 2592241 agacacttta attacccctg ctttatctgc ttttttaacg catatgaggg atcattttca 2592301 gataaagagg ccagatcaat cgtaaataaa tggatggaag gcatgcttcg cctcaaaata 2592361 cccctgatca gttgtctgat ataaaaatat aggcgcatct caatgtttgt atagagcaaa 2592421 aaagcaaact tcggtatgta gtttgctttt tcttcgtgat tttgcactct gaatcgtgaa 2592481 acctagtcga tattaggatg tagattttcc tcattcaaag aattttgaac gaaggtcatt 2592541 gccctagaca cttggttgcg tcttgaagtt aaaggctgac tatttcctaa agcgtcaatc 2592601 gctctcacaa ctattaaata ttcacctaca gatttcgggt gacaacggga agattgatat 2592661 tttcggttgg acaggggcag aacatccaat tgtaacagtt gaagtatcca ctgatggagg 2592721 agatcctgca gatctgagtg atattgctgt tgattgatca acttgttttt gttcggaata 2592781 tactcagtat atagccgcat attcctcctg caatagctgg aatgagccac cccagcccta 2592841 tgttatacat aggaagaatc tgagtgaaaa tacgattcac aacttcaatt tttattccag 2592901 ccgccttcaa accgtcaaat aggctgatga tgaatgcgaa taataaactg ccttgataca 2592961 cttctgtctt ccctttaaat acagaatgca aaaacgttaa aaatattaag gaaatcgcga 2593021 taggatacat cgtcagtaag acaggcattg acaccttaat gagctgggtt aatcctatat 2593081 ttgcgacaag cgtactaaac actgataaaa cgacagcaat ttttttataa gaaatgttcg 2593141 gaaataattc atgaaaaaat gaagaacacg ctgtgatcag cccgacactt gtcgtcagac 2593201 acgccactgt aatcattaag cccaataaga ttgaaccata agatccaaaa taataggatg 2593261 aaaccttagc caaaacctct gctccatttt ctaaaatccc cagttcttca acgctggaag 2593321 cccccatata ggaaagggct gtatacataa ctgctaagag tacagctgca atcgcggctg 2593381 cttttgcaca aacaactatc agctgttttt tggtagaagc tccttgttct ttcaatgcat 2593441 tcacgatgat aattccaaaa acaaatgcta caagggcatc cagagtgagg tatccttcct 2593501 gaaatccttt aaaaaacgct tgtgatgtgt acccttttga tggtgcttga atggttccaa 2593561 ttgggcgaat aagagctacg gctacaagca atccgataaa tgtcagctta attggcgtca 2593621 aaaatttacc aactatatca atgatttttg aaggattgag tgataacaag catgccaatg 2593681 cgaaaaataa tattgtaaat atgatcaatg agacagggct tgcatcattt gataaaaaag 2593741 gttttacccc aatttcaaac gatacgtttc ctgatctcgg gatagcgaaa aaaggcccga 2593801 ttgccaaata gagaatcgtc gtaaatacaa tgccaaacac cgggtgaaca cggctggcta 2593861 acgactgtaa gttttgttta cccgaaaaaa caaatgctgt tatagccagt aatggcaatc 2593921 caactccggt cactaagaaa cctgcattag cgacccatac atttttcccg gccaattgac 2593981 caagcatagg cggaaaaatg agatttcctg ctccaaaaaa caatgcaaat agcattaatc 2594041 ctataatgat gatataggaa gcagacactt tttttgacat tatatatcct ccgattaaag 2594101 tagacacttc ttgaatagcc aggaaacatt acagatgcta tttgcactgg cacagtgttg 2594161 attccaaaat aagcttgtgt cagttttata tatttttatc aagttaaata aaagcatgat 2594221 cattttgatc gtttccgata tcggttaaaa aaccaattgc accaaaacca tataaacaac 2594281 ggttcccccc gctatggaaa gaagcatatt tttcttccac aagtgaagca gtacaacagc 2594341 agctgctcca accaattcag gaatgccatg acttccagaa agtagactca catctttcaa 2594401 acaataaatg actaaaagcc cgattaccgc tgatggcagc actttaccaa gatactgtac 2594461 atatttcggt gtcggtttgc cagacgggaa aatcatgaat ggaaggaacc gtgtcagcat 2594521 tgttccaagc acgaccattg cgatggtgat catttgctgc gtcatagtca tcgtcatacg 2594581 gaaacctcag ctttctccaa tggttttctc agaacagtca gtacccctaa aatggcgagc 2594641 atagcaggaa taataaattg gtttccgcca aaaaggataa gactggctac tgaaagtcca 2594701 agtcccgtga gagcactgta atgctttttc tctttcatcc attgttctat gaatatcaca 2594761 ataaacagag cagtcatcac aaaatcaagc ccttcggtat taaacttcac gtacgaccca 2594821 aaaatacctc ctatcgctgc ccccgcgacc caatataaat gattaagcag tgtcacaaaa 2594881 aacataaacc agcccttatc aacattcgcc ggaacattag cggtataatt gatagaaaat 2594941 gattcatcgc acattccgaa aatcagataa agctttttct ttccagtccc cctgtactta 2595001 tccaacatgg aaattccata aaacaaatgc cgggcattga ccattaacgt caaaaaaaga 2595061 gcattcatag ggttgaacgc accaagtaaa aaattcgctg caacaaactc cattgagccc 2595121 gcaaatatca taaaactcat gatgattgga tagattgcgc taaatcccaa agaatgcata 2595181 aagatcccat aagctatccc caaaaataaa aaccccgcaa aaatcggaat ggtatatggg 2595241 aatgcagaac gaaatgcagc ccatatttga cttctcttat tcatatgagt gtttatagca 2595301 ggagagctta aatgtaacga ttctttattt ttattcaaat caacaacctc ctacatttca 2595361 tcaattggca cactgacagt tcttttttct gtactcatga ctatgcttgt gtcaactcca 2595421 ctaatagcag ggttctgcat taatgaatca atgataaaat tccgataact ctccatgtcc 2595481 ttcgccacaa tcttaagcat atagtcatgg cttcctgtaa gtgtgtagca ttcttgaacc 2595541 tgtgggaatt tgtttatatc ctctaaaaat gaatgaattg tctccctatt taagggtgat 2595601 aagttgatga gagctagtgc tgtgacttcg attccaagtt ttttctcatc aacaatagtc 2595661 gtaaactttt taattatacc tgcttctact aggttctttg ttcttgcaag gcaagctgat 2595721 ggtgaaagcc caattttctt agataaattt aaatttgata ttgaagcatc ttcctgcaaa 2595781 tctcttaaga tggccttatc agtttcgtca agcataatac ccatttcaca acccccaata 2595841 caacttaaca gaattatatt tcatacaatt taaataataa cgaattttta ttcgttaatc 2595901 aaatattatt taaatttaaa tccttttaaa gtattattca cagaataaaa ttatcctcgc 2595961 gattaactca taatgaaatt aacttacatc agaaagaagt catgggagag ttatgtactt 2596021 gtgtgacttg ataccaacat cataagaaac ttatcagaag ccaaaaagtt attgcggtct 2596081 caccgaaaat tgaatttgcg gtgccctatt gcctttttcc gcgaacgaaa attgttaaaa 2596141 ttcgcaaaac agaaagtcta ctctattatt attttaaatt cgtcctttag ttcttcttga 2596201 gcctcttgta taacttctaa tacatcgtca gcgtatgaac ctaaaaatgt attgctgaac 2596261 tcaaaatttt tcaagactaa agtgagcggc aaatccaccc accctgtcag gcaatcccat 2596321 aaagcgtcta aatttctccc atagtagtct gggaagtcta gtttatcttt taaatcatca 2596381 tgtaaaactt ctatattttc aaagtctctt ccatctatta ttatttttct cattagaaac 2596441 tatgccctcc attattttat cttaacaaac gtttactatg taacagctgt ttgtccaaat 2596501 gaggctgaaa acaaataaaa aacaccgata ggatgaaact attggtgttt gcaagacatc 2596561 ttcatacccg gtaggcataa ataatgctaa actttgtttt taaaaagcta tcatatcaaa 2596621 tttttatgtt acagctttta ctatcgttta atctaattga ggagtaaaac aagatatgtt 2596681 tgaaaatcac atatccccta aaaattaaaa actaatcggc agttcttcga gtgctctcat 2596741 cagaaaattc cctttccatt tcatttgttt cttttcgcct tttaactgta tatttggaca 2596801 gcggcgtaat aaggtggaaa tcgcaatctt tgcttctaag cgggctagct gtgcaccaag 2596861 acaaaaatga ttgccatggc caaaagcaat atggcggttg ttctttcttt caatatcaaa 2596921 tatgtcggca tttggaaata tcttttcatc acggtttgct gatgctaaag aaatgatgat 2596981 cacatctttc cgtttaatct cctgcccatg cagtataaac ggttcagccg tccagcgaat 2597041 tgtcgttagc tcaacagggc tgtgaaaccg caatgcttct tctatggctg aattcatcaa 2597101 gtccggctgc tggcggagct tttctagttg atcatggtga cacatcagag catatgtcat 2597161 attggtgatt aagtttacgg ttgtttcatg acctgcaacg ataagcagca taatcatcga 2597221 gtacaattct tctgtactta attgtgtgcc ttcactttcc gcttgaatta atgcactgat 2597281 taaatctcct gcaggttctc tccttttttt gcgaactaag gattccagat attcaacaaa 2597341 ctcccctaac aagtggtcat tctcctgaag tctttcaggg gcatctgaaa aatcaataat 2597401 tgcttgcgac catactctga atttttgacg atcttccaag ggaatgccga gcatttcact 2597461 tatcacgata atcggcaatg gaaacgcata atcgtctact aggttcatga atttgttggg 2597521 ctgcacttta tccaataaag aatctgcgat atgctggatt ttgtcttcca actgcaaaat 2597581 catccgatgc gtaaatgctt tttgaacaag agttcgcaag cggttgtgat cagggggatc 2597641 tgaattaagc atatgttttg ttaaagtctc ttcattcttc aatagagcag gacgtttttc 2597701 ttttgcggta aatacatttt catagttttt ctttaatttt tcattcttta ataaatgtat 2597761 tgcatcatca tatctcgata tgagccagcc tttccccaga gctcctaaag ataatgggta 2597821 gagagcctgt gattttcgca attctttata aaattcatac gcttcatctt taaatgctct 2597881 cgaagacaat tgactttccg tcaaaatggt tacactcttt ttttcttttg aagacattca 2597941 ttcgacctcc atctttgaaa ggttatgata atctttaaat ataaaatcag gacgatttgt 2598001 aaaatgatcc attgagatca gtattcatga taagggccaa aatgccgtcc ccgcattttg 2598061 aaataaaaga tatgagacag tcattaatca ttttgctgcc taaactcttt ccctgataaa 2598121 atggcgaaac tcctaatact tctatgccgg ctcttttaag gatttggaaa attttttagc 2598181 cccattttga ttaatgttat cccccctgct gctatataat cgatcaagtt taatgtcggg 2598241 tttatcacga tgttttaata gagcggcaac aaccatttca ccattctgaa tgccaacaaa 2598301 aaagaaatgc tttttaaaat atgctcttgt cagtacttta tgcatttcaa aaataaatga 2598361 atgatctttt tttcgcgttt tacgagtaaa tccataaaag gatattgatt gaaagattga 2598421 tggaatagct ttgccacttt gcttacttca tctgctcttg cttgtcgata aagaaacatt 2598481 gatgcacctc ctctgagcag taaagcagga aatcgaatta aagcgccctt cctattggaa 2598541 aggcgcctgc cgttttactg tgccaaaatg tttttcatca gtgagttttt ataaaatcat 2598601 ttattaattg atcagttgtc aatattgtgg caaattcatc atgcaatgta gctagagata 2598661 tattatgaat agtcgccgca tcataatatg tatcattttg gtctctcatt ccgaaggctg 2598721 ctgttgcatc tgaaatcagg tatgtatcaa accctaaatt accactcatt cttgtggtgg 2598781 ttgatacaca gtgaggcgtg gttaaaccag ttatgactac agtggttatt tcatttaatt 2598841 ttaagaattc ttctaaattc gtaccaataa agctgctatt tactgtcttg gttataatga 2598901 cttcttcatc cataggctta actatttcct ttattgcaaa cccttcattc tttggatgga 2598961 ataaagaatg aggtttatca gaagtgtgtt gtatgtatat gactgtccat cctttttctc 2599021 tccataattc tagtatttta ctaatgtttt cttccgcctt tacgttattc cgttcccccc 2599081 attttttatc atcgaaggct ttttgtacat ccacaatgat taaagctttc ttttcttcca 2599141 caagataccc tcctacgtag aatttctatt tattactaca ttctaaatac aaattttact 2599201 tttgtacaat tgtttaatga tgaatttcaa atgagcgcct tctttattgg aaaatgcgtt 2599261 ctatactgca actgtgccca agccgttaac cttcaaatct aatctgagaa tcactggctc 2599321 tacagagaat aataaaaaac actctaataa cgagtgctga aatgaaaaac tattgattta 2599381 gaagccattt gatacgctca gctgaaatga tgtagtggag tattataaga cataaaaaga 2599441 caatactaac tggttttaaa taactaaaat aaagcgctgc aacagccatt gcaaagatca 2599501 ataattcaat aactaacctt gttactccgt ttacagctat tacagtttgt ccgcttcgac 2599561 taggatcatg aggtactgca aatacagacc agacaatcat aactgcaata ggtaaaacca 2599621 aagttaaaac atatttaaaa taaccattaa agcttatcca agcatacacc cctaaggaga 2599681 ttagtgcagc aatttcaagg gtgaatctta aaagtaaatt agtctgattc agtttttcca 2599741 actcctctat aaaaaacacc cccgcaggag atgctctttc tctgctttat ttcagcgtat 2599801 aaaaactttt ctgttcttcc tctttagatt ctattgtagt tttcggcgag attacctcta 2599861 cttttgaaga gatgataccg actgctgctg ttaccaatgc tccgataata gaacgatgat 2599921 aagtataatg aaatatgaca acttttcccc tcctattcag ttaattatcc aaataatcag 2599981 gaagttgtct acaatttgca gaatttgtcg aacgaagtaa agattatacc tgggaggctt 2600041 tactcattgt atgaattaca gtaaataaat tgccttccct tttgagaaga cgttccaact 2600101 cagctagact cttccaatag gcttcctttt ggcgcagctg cttttattca aaaattgagc 2600161 aacacctgaa tgtttcattg gaatttctga accatcgatc gctgctgaat ttgttgcaaa 2600221 tgcatacgta ggagtagtcg aatggtggtt gaaaaatgaa atgccttccc cacctcgagt 2600281 gatggcagaa aaagcggggg ttttgttaga gaggaatcta tagatatgtg tatcgaagat 2600341 ttgacagcat taaaaattat acttacatcg ttgggaacag gccaacaata aagcggaaga 2600401 acgttgtcat ttgaagtggt ttggaataaa aatgattcga atatgttctt atcattgtaa 2600461 acgaacaaaa aaagaacatg ttttgaaaaa agattgatca aaacatcttc ttatatgttg 2600521 tcatagcgta actttttata aaaaggttaa ttacattttc ggggcttcca aaccaaattt 2600581 tgcccattct tcttttgctg gaccataaat acctggaaca gttaaacctg cttgtctcat 2600641 aagaacagtc atttgtcccc gatggtggtt ttgatgttga attaaaaaca tcaaaagtga 2600701 accgttaggc atttgttgtc caataaagtt gatacgttct tgaagtgtat ggtcagtcca 2600761 ttgggttttt aatgcctgta caaatgcatt actggcttga tgatagctgt cagctataaa 2600821 ctgagcagaa gttggaacag gataatcttc agctggggct tggaacgtta agtctgtgtt 2600881 tgaggtaatg atgccaatgg cagcaacagt atgccaagca atacggccta gagtccaatt 2600941 ttgtgaagtt atttcttgtt taagtgattc atcagtcaga ctatttaata gtttctgtgt 2601001 agcatctgct tcgaactccc aagatttcaa aaaatggtct aaggtttgaa acacaaaaat 2601061 cctccttttc attcttttgt tttttcaatg tgcttatagg ttaattataa tgcctccttt 2601121 cgttaaaaag aacaaaaatt tcggacaaga ataatcatag taaaatgcgt agacattctt 2601181 aaacgtaacg atttacgcat ctttttacaa acatctgact acttggtctc cattgtcagc 2601241 gagaatcaaa tatcatatga agacaatcct atattcttat cactttactg agcaataaat 2601301 accttccgta tacttagtaa taccttcatc gtaatcagga tacttatatg caagaccttc 2601361 tgatacagct tttgaatact ttctaaataa tgcatagcaa gtaaataaag acttccacat 2601421 ttcctgatac ccattcacag aatatgtaga catgagttcc tcccattctt tatttgaaag 2601481 gtaccgcttc ataaatttat agttcttccc catactaaat gaataccctt tctgagatgc 2601541 gatatgccag gccatcattc tcaataaatt aggacgtaca atttcattta aatggtcaat 2601601 ggcaaaaagg atttcatttc ttgctagtcc ttttactacg taagtcgaaa ccatccagaa 2601661 ctcattacag caatcatcaa attcccttgc agtcggcctt tttatccagt attggcgatc 2601721 atttggggtc actttatagt tgatgaacga atccttatca agcaatacct taaccaaacc 2601781 atcgttatta gcaaaataat cttctgcttc acgaattgga ataagggtta gatctaattt 2601841 gttgccatcc tcaaaaagaa taatgtatga aaaccaatta cctaattcgg gaggaaaaag 2601901 ctccatatct tctggttttt gcatcataat gcgcttccca aagatttcga gccactgatc 2601961 attttcttta aaagattcta catcagttac aaaatacgag atgtcataat cttggaagtt 2602021 gtcaggaggg atatttctgt ttgtacgtga cccttccaaa gtgaccaatc ggattctctc 2602081 atcgttcaaa gcaaagtcca aaaaaatgtc catcatttcc tgctcacttc gcattacatg 2602141 ttcctccgtt tcagccttaa tatctaactg taaaacgtct tatagatttt tttactcttg 2602201 aatgtgatgt attcttctaa gctttatttt acatgatgtt ctcctatata tcattcaata 2602261 ttaagatgca agacatctca aaatcagata tcaactatga cggactacat gaatattcag 2602321 ttttttgtag agccgccatg ggacgacact atctttgaca cactttaatc ccccctgctt 2602381 tatcgacatg ttaactggta tgagagattg acaaaaagaa ggaaaacgat atatttaagc 2602441 gaatacgagt ttttgagtaa attttaaaat gacacttttt tcaaaaatca tgtcttaacg 2602501 ggaggattcg gtatgaatga atttatgaaa aagttttctt taacaaaacc gattattcaa 2602561 gctccaatgg ctggcggtat tacaaagccc cgacttgcat ctgcagtttc gaatcaaggt 2602621 gctcttggca gcttagcatc ggggtatctt acgccagacc tcctagaaca acaaataaaa 2602681 gaaatatttg agctgacaga cgctcctttt caaattaatg tgtttgttcc gctaggtcta 2602741 gagatgccac caaaagatca gattaaaaag tggaaagaaa acataccgtt agctaatcaa 2602801 gtaaatcaat tcacatctgt acaagaagag tgggatgact tctatcaaaa aattgatcta 2602861 attttaaaat acaaggttaa ggcttgctca ttcacttttg atctgccgcc tgaagacgca 2602921 gtaaaggagc taaaaaccgc tggatgctgt ttaataggaa ccgcttcaac agtagaagaa 2602981 gcattgttaa tggaagaacg gggaatggat atagtagtcc ttcaaggaag tgaagccggt 2603041 ggacatcgcg gagcattctt accttccaaa ggtgaatctg ccgtaggttt aatggctctg 2603101 attccacaag cagcagatgc actgagcgta cctgtcatag ctgctggggg aatgatagac 2603161 cacagaggag taaaagcagc tttaaccctc ggagcccaag gcgttcaaat cggttctgcc 2603221 tttttaattt gtcacgagag taacgcacat ccagtgcata aacagaaaat actagaagca 2603281 aacgaagcag atacaaagct tacgacatta ttttcaggta aagaggccag aggaatcgta 2603341 aataaatgga tggaagaaaa tgaacagttt gagacacaaa cccttccgta cccttatcaa 2603401 aatacactaa cgaaggcaat gagacagaag gcttcacttc aaaataacca tgatcagatg 2603461 tctttatggg caggtcaagg gatacggtca ttgactgagg aaatttcggt taagcagctt 2603521 ttaaatcagc tttgccaaga ggatataaaa atataggcgc acctcattga tagagcaaaa 2603581 agcaaacttt gacaggcagt ttgctttttt tttcgtaatt tcatccactg actctggaaa 2603641 tctaaatact cctacatttt caaagctaat ttgaatcggg ttatcaatca tcacattgat 2603701 acgatgcgat cttgataatt tcaccacaac cacaatacat taccaacatt tcgatcttat 2603761 ctccccttct caagttttgc tccctattcg aataatcgat agctcccata ttaaatttga 2603821 atagtaaaat ggttcttttt cgtttgattc agatgatata aagtcatatg ataaaaaaag 2603881 aatgagacag aaagcgtgag aagtgatgaa aataggattt tttgattcag gaattggtgg 2603941 catgactgta ttgtatgagg ccataaaagt tcttccttat gaagattaca ttttttatgc 2604001 agatacgtta aacgttccat acggtgaaaa atcaaagggt aaagttaaag aatatatttt 2604061 caatgcagct gaatttctgg ccagtcaaaa tatcaaagct cttgttattg cgtgtaatac 2604121 agctactagc attgcgatag aggatcttcg gagaaacttc gactttccga taatcggaat 2604181 cgaacccgct gtaaagcctg ctataaataa atgtacagag gaaagaaaaa gagttctggt 2604241 agttgctact aatttgacgc ttaaagaaga gaaatttcat aatctagtta aagaaattga 2604301 tcaccatgac cttgttgatt gcttagctct tccaggacta gttgaatttg ctgagaactt 2604361 tgattttagt gaagacaaaa tcattaaata tctaaagaac gaactatctt cttttgatct 2604421 gaaacaatat ggaacgattg tgttaggatg cactcatttt ccgtttttca aaaacagttt 2604481 tgaaaaactg tttgggataa aagttgatat gatttcaggc agtgtcggta ctgcaaaaca 2604541 gttgaaaaaa gttcttgcag atcgtaacca gcttggtaaa ggatcgggct caatcacctt 2604601 tttcaattct ggccataaaa ttgtggacca agaagtcata tcaaagtaca aaagattgtt 2604661 tgaaatatta gatgaaactc aaaggagtca tgttggacat tgaatgtaaa tgaaaaagac 2604721 aatctcctga agagaaacat gaactaagaa gcgggcttaa aaagcccact ttttttctaa 2604781 caaacaattg agttatacac acatatctga ttacagtgtt ttctctcttt cccctcttat 2604841 ttctcccccc tctctatagc ttttctattt caataaaaca caagtctcga ttgaaaagtt 2604901 atcgtaacat ttacacttca caggagattt ttcacgattg cgaatcgacc gtttgccaga 2604961 tgcacaaagt cataatgtgt aaattctgta tctatgtgca tgtttattat ggaattattt 2605021 tcataatgtt ttataataca agatgatagc gttttctaat tataatgata gggggaaata 2605081 atgatgatga aaaaaggtct gcttgcgggt gcgcttacgg caaccgtgct ttttggcaca 2605141 tgtgcagtag atgtaccggg tattattagt ccaaaaaccg cagaagctgc atcacagcta 2605201 actgatggaa tcggcgggag ggcttacttg aacagtaatg gtgccattct tgttacgaaa 2605261 atccagcttc ctagctccac tcaggtttca aatgggacag cctacatcta ctctggtttt 2605321 agcggaggca cagaatccga tatcgggttt cagtacagtg ataaatataa tgtatggaaa 2605381 ccatatatga aagtcggttc aaaaggacag gatcaggttc agtacctcga aggaggaagc 2605441 caattcacga atacgaaagg cttccgtccc ggcagcaccg tacaacttac catctacaaa 2605501 aaccttaacg gcaatacccg cgctacatac tggggcacga acaatgccgg atacaacggc 2605561 cgtctcattt cagaaatcag caaaacaaat gtcggctcca tctcaaaatg gaaagcgctc 2605621 gctacagttg caacaacagg gtcacgccaa tctatcaaat caaacttttc aacatctttt 2605681 acaaacatca ccatcgacaa caaagcaata acacctgtaa ttgatacaca agacttcgct 2605741 aaagtaacag tctcaggcaa cagtgtcagt ttatccgttg tcaaaaatta aaacatgtta 2605801 aacatacaat gcgttaggct attgagaagc tctcgatagt cttaaagggg gcttaacatg 2605861 cccctttttt catttcaatt taactttcag ttagcttcgg tacatgccgt ctatccccgt 2605921 cttttatctg ggtgaagtaa gggcagctcg ccccttctga acctgttcca tttgctcaac 2605981 gcaaaaggtg tgcatcactg tcttaaaaat gttaaaacaa atagcagatg gtgcacttta 2606041 tttttagatg aggcatgctt acgctcgata tgcaagtcaa atgattaagg gtctgcaaga 2606101 gagagaagtt ttgggtgtac tttcataaaa gagggatggc ttcatatagc tcgattgcat 2606161 caggaagatt agccaacgat tggccgagaa caacacatca ctttgaaacg gattcattcc 2606221 aaaatcataa gtatgatcca ataactaata aagatcagtt agcagtccag ccttaaaaat 2606281 atttttacat caattaaact agcatcacta tcgaataagc tcgatctgca tatcatgtac 2606341 tatcctcttt taaggaaggt gatgttatga ggtcatttcc attaatcgta gttctattca 2606401 tcctattaat catcgttggg acatctttct ttggtggcta ttaagaacac accttacctc 2606461 atatccatca gacgccataa gaaatcttta tggcgtctgt tttttattag atttaaacaa 2606521 aaccattaaa gtgggccatg caaacacacc tatggagatt actgccacga cttctttgtg 2606581 agggaattat tcttcccttt atggactatt gtcgatcaaa agagaaagtt gaaatgcatt 2606641 tttatggtga gatgaatcga ggcttagaca tataaaaaac cgcaaagctt tcttgaagaa 2606701 gctttgcggt ttttgggtct cttctttgct tcatataagc caatagattt caagcgtaat 2606761 ccactgccat acatccaatg attttttatt ttgaaatagg tttcttctac tcttcatgtg 2606821 agatgactca aggtatgcca cgtcacaata atatggcgga tactgaatgg tctcaatcag 2606881 ttttttcccc attctatcaa ttctccacag aaaaaatggc tatggcagaa caactttcat 2606941 agagtaatca tcatttaatg agccatcatc tcatgggcaa tatcgtgtcc atccattttt 2607001 gacgggtagt aagtaggcca gtttttgact tcatcaagta aagcttcacg gtcgtccccc 2607061 caatagagat ggtaatgact agctttagtc gggtaaatac tatgatcact aaactgaata 2607121 tactgaggca gcccttctgc ttttttagct agtttgaata tgtatcttac ccctctattg 2607181 cccgcatcat aggttagaat ttcgtatccg tcatacgtat acttaccaga atattctttt 2607241 ccatttttga agaacgttac agtatctttc tggattacaa tacggtcaac atctgtttga 2607301 tagccttttt tataatactc tttatattct tcagctgtct tgccgccttc gtgttctgat 2607361 ttatatgaaa acacttcgtc aagagtacca tcttgcaggt atggatatac agattgccaa 2607421 tctccttccc aatcagaaag taagcgatcc tttacttggc tgtttttaaa atagccttca 2607481 tatatttttt ctgtttcttc atcatgcgca tgactatgat cgtgagaatg ttcgtgtgta 2607541 tgactgtcag atgtttgctc ttgcgttttg gaagagtctt cttcaactgc tgaggatgat 2607601 gttgtttgat tagactcacc tgcagaagaa ccggaagtct gacatcctgc caaaactagt 2607661 aatgaaccaa tcgttaatat gcctagccgt tttgaaaata aaatgttcat tccaacactc 2607721 cttttttatt aaatcgaaaa cattacgatt tattatacat acatctcttg caaacatcaa 2607781 aggaaaaatg ctcttcatgc ggatggccta ttttaaagga ataactgact atgttcatca 2607841 gttattcctt taaaatacga aagtctacga tatttccata tcgatccgct tcaatgtgac 2607901 agcacccctc aagcagctgt tttaattttc cacgtccgcg ttgtaccctt gattttgctc 2607961 cggagtaaga aatgccgagc ttttcactca actctttttg tgataacccc tggaaatcag 2608021 ttaactcgag cgcctctcga tacttttcag gcaaccgttt gatggtcgat cgaatacaca 2608081 cagttgcttc cttggtgaaa ttttcttcct ctgcactgtc attaaaatgt agaacatcag 2608141 gcaatatttc gcttgttttt tttgtacggt aaaaatcaat aatcgtattt ctagtgatcc 2608201 gataaatcca gctgtcgatc ttttgttcat cgatcagatt tgggagatgc acttgtattt 2608261 tcataaatac gatttgcaag aggtcatcaa cgatagattg atcgttaacc ctatgtgaaa 2608321 tatatgtttt taacggctga tgaaattgat cccatagatc ctctatattc atttgaaaaa 2608381 acctcctata attttgcgtc tgctttacat ttgcttcgtc tttttaatcg taacaaagag 2608441 caaacaattg ttgaatcaat tgtattgcag ctgttgccaa aaataatgat aaaggagagg 2608501 tttgttgtgg agtataccta tttagggaga acaggattgc gggtgagccg tttatgttta 2608561 ggcacgatga attttggagt tgatacagac gaaaagactg cgttccgtat catggatgaa 2608621 gcacttgata acggcattca attttttgat actgccaata tttacggctg gggcaaaaac 2608681 gcaggattga cagagagcat cattggaaaa tggtttgcac aaggaggaca gcgccgcgag 2608741 aaagttgttc tggcgacaaa agtatatgaa ccgatttctg atccgaatga cggaccaaat 2608801 gatatgaggg gcttgtctct atacaaaatc agacgtcatc tggaaggatc actgaagcgg 2608861 cttcagacag atcatatcga attgtaccaa atgcatcata tcgataggcg gacaccgtgg 2608921 gatgagatat gggaagcttt tgagactcag gttcgctccg gcaaagtaga ctatattgga 2608981 tccagtaatt ttgcaggctg gcatttagtt aaagcgcaag ctgaagctga aaaacggcga 2609041 ttcatgggac tcgtcactga acagcataag tatagtttat tagaacgaac agctgaaatg 2609101 gaagtgctgc cggctgcacg ggatcttggt ttaggagtag tggcgtggag tccccttgca 2609161 ggagggcttc ttggcgggaa ggcattgaaa agcaatgccg gaactcgtac agcaaaaaga 2609221 gcagatttaa ttgaaaaaca tcgtttgcaa ctcgagaaat tttcagattt atgcaaagaa 2609281 ctaggagaaa aagaagcaaa tgtggctttg gcatgggtgc tggcaaatcc agttttaact 2609341 gcgccgatca tcggaccacg aacggttgag cagctgcgtg atacgataaa agccgttgaa 2609401 atcagtctgg ataaggagat tctccgcatg ttaaatgata tctttcccgg acctggagga 2609461 gagacacctg aggcatacgc ctggtgatac attcattact caatactgac atttttctta 2609521 aatatttata ctgaactatc atattaagaa agacaagagc atgtttgtct cttgtctttt 2609581 ccacatcgtg ctgaaaatgc tggctaaaca tcgacaaaaa tgctgccgct taaaaaagaa 2609641 ccctaaacaa tagagtaact ggaaagacaa ctggcttgat cagcttggga cccctttcag 2609701 ctgtatttaa atcaatcaaa ctaatgattc attggcagtc taaatattat tattgtttct 2609761 ttacaaaata gtaatagccc ctgtaatgat tgctaacaac gtaataacta atgatgtaat 2609821 tacagcccac ttaacggcaa acctttgaaa tgaccccaag tccattttaa gcatgcttac 2609881 tagcaatact gttgacgcaa ccaatggact catcagatga accggctgcc ccattataga 2609941 agcccttgca atttctactg gttctatacc atatgctgag gcagcttctg caaagatagg 2610001 taccatacca aagtaatatg catcatttga taaaacaaaa gtaaacggaa tactagtgag 2610061 tgctacaata acggggaaaa accctcccat tgatgagggg atgatggata ttaatgatcc 2610121 tgctatggca tccaccatct ttgtcccgga taatatacca gcaaatactc ctgctgaaaa 2610181 taccaataat accacggtta tggcattacc agaatgctcg gcgattcgct ccttctgcat 2610241 ttttacattc ggataattta tagtaagggc aagaacaaaa ccaattaaaa ataaaactga 2610301 cggatgctta gttccaagca caataaacac catgatactt ataacgagga ataaattaag 2610361 atatattaag cgtggccttt tcaattgttc gctctccaaa gtagcagcca tataagattg 2610421 agagctgtcc tttgttatat gtctaggctc taattgaacg atgcctattc gattcctctc 2610481 tttccttccc attagaaaag ccagaaatat cacacaagca atacctccaa gcatggtcgg 2610541 aagtaatggc acaaagaaat ctgaaggatc caaacccagc actgaaatcg ctcttgtagc 2610601 tggtccgccc catggagtca ttccgctaac gatactcaac gacagcattg ctaatgtcgc 2610661 cataaccatg ggattcatac caattctttt atacaaaggt aacattgctg agactgttat 2610721 catataggtt gttgtaccgt ccccatctaa agcgataagc attgccaaga cggcagaccc 2610781 tatcgctatt ttcacagggt ctccctttac tatagataaa attttttcta ttagcggatc 2610841 aaataaacct gcatcaatta aaattccgaa aaaaagaata gcaaacaata gcaatgccgc 2610901 tgaacttgca actgtttgaa ttccttctaa aatcatgtcg ccaataccct taccaaaacc 2610961 tccaataaga gcaaaaacaa tgggagtgat ggtcaaggca acaataggcg agactttctt 2611021 tgtcattatt aatattgtaa aaacagttac catcgaaaaa cctaaaatag taagcatatt 2611081 acacctccaa gaatgcgctt tcaaatgact tttgattaac atatcttata cggtgtaata 2611141 agttaaataa atattttttt actgtgtttc aaaaaaaatt ctatcataac tttaaatggt 2611201 taccatttgt tcacccttta aaaaatcaat gaatgcttta acgagtttga ttcctaatga 2611261 tttttgatcg tacattagcc aagtatctct cattagaggc ttacccttag cattatacag 2611321 ttccattgtg tacaaatgat cagattcctg caggcaaatt tctggtgcta tggagtaacc 2611381 aagaccatgc tttaccatct ctttgcaagt ctcttgtcga tccacttcca ttgcaataat 2611441 gggggcttgt tttagattcg tatgcatcca atcttctata atcgttttta aagaagcatc 2611501 cgttttatat ttgataaaag gtaaaaaagg aagttgctct atcgttattg gtttttttga 2611561 gatgatatgt aatttttccc gtgtcagccg ttcctccacc cctttccagc gatggcttcc 2611621 tctcagtata ccgacttgta caataccagc atctaataat ttcatgacat ctgtgctcca 2611681 gcctgtttgt acactatatt ggacattagg atacatagtg gaaaattccc ttaataactt 2611741 agggagctta tattgagcga aattgcttga tacccccagc cttagatgtc cttgcacctc 2611801 tttgcttaga ttagagatat gatctttggt atcttgaagt tcctgtagca ttcttcttgc 2611861 ataagcaacc aagtgttctc cttccgcagt aaaggtaatt cctttatgcc ttttggtgaa 2611921 taattcaatt ccgaaaatct cctcaatctt tttcaaccga taagtgatgg aaggctgtga 2611981 tgtaaataat cgttctgctg tttttgttac actttgttct tcgtgaagaa ttttcaataa 2612041 aatccaatct ttctcatcca ttttcatctt cctttctagt ccttctttca caattataaa 2612101 agttttttta tcgaatatta agaaaactta tattttattt ttattttttt accttctaca 2612161 ctaaaaaaca taaaaaatac tacctttaag atgaggatga tgacgatggt caagacgaat 2612221 gtaacaatca tgagaggcgg aacaagcaaa ggcgtttttt tccacgaatc agccatgcct 2612281 aacaataaaa acgaatggga gccctttttg cttgatgtca tgggaagtcc tgataaaaga 2612341 caaatagatg gtttgggtgg cggtaattcc cttactagta aagtggcaat aataaagaaa 2612401 gcatatactt cggatattga tgttcactat actttcggtc aagtcagcat ttcggaagaa 2612461 aaggtggact ttaaggggaa ctgcggaaat atctccgctg ctgttggtcc atttgctatt 2612521 gaagaaggac ttgtaaaagc gaaagaacca atgactgcgg taaggatcct gaataccaat 2612581 acgaataaaa tgatcattgc ggaagtagaa gtggaagacg gtcaggtcaa atatgacgga 2612641 gatgttacga tatctggagt acctggatct ggatctccaa tctatttaaa ctttcatgat 2612701 gccgctggtt cagttaccgg tcatttattg cctactggaa atagttcgga gtttttagat 2612761 acaagtcaag gccaaataga ggtgtctatt atcgactatg caaatccatt agtttttgtg 2612821 gaagcgagca gtatcggcct ggatggaacg gaacttgcag aagaatttac tgatctacag 2612881 ttggctcaat ttgaagaatt aagatccatt gcggcagaga aatgcggctt tgccagtcga 2612941 ttttcagcta caaagttatc gccggctgtc cccaaactgg ctatagtagc aaaaccagag 2613001 aaatataaag atagtacagg tgcttggcat tcaagcgttg agatggactt acacatcagg 2613061 atgatgtcca tgcaaaagcc acatcaagca ctggctgtca ctggagcgat atgtacaaca 2613121 agagcccttt cagtggaagg tgcaatccct gcaagaatag caaaaaacca ctctacaaag 2613181 gttcggctag ctcattcttc tggtattatt gaaacaatgg tggagcccac tggtataaag 2613241 atcgtccgta ccgcacgacg tattatggac ggaacagttt atacgcatgg agactatcaa 2613301 atgatgtaga tggactgtgc aaaaagcctc ccccctttcc atcgttaata gatggattga 2613361 atgcgccttc ttgcacagat ccattgtaat cttgcatggc tttaaaaaag cctctatatt 2613421 gttttttatg aaatcgccaa ggtcctttca tgtatctgcc tcaagcatga cataatcatt 2613481 atagagaaaa ttgaatactt tttactgcaa ataaaaagat accaacatca ttggtatctt 2613541 ttagattgag ttcatctgca gcggtttctt ttcctcactg cttatttgat tacaaaatta 2613601 ccgtactcgt ttgaacgaac atgaatcggt ccgtttagat tatagttgtt ctccttggcg 2613661 atagagcgaa gcacgtccac acgggcaact gattctctcc attcgtcacg ggtgtcatga 2613721 ttggccggat tcatcagatc gtcatagcgt acgtccaaga atttattcaa ccacttcttc 2613781 tcgtctattc cgtctttagg tgatccgccc gcttttttgt tcgtacgttt aatcaaggca 2613841 taaaaagagt cagggtcatc accatcgcca tgctgaataa ccgtatcgta catcacagct 2613901 cttgccaatg ctgtttttag tccggcatta tccgatcgtt tcatggcagg ctgataatac 2613961 aaatggtcat ttactttgtc ttgagcggcg cgaaattcct tatcatttgc aagcgacttc 2614021 caggcagaag cgaatccctt gagattgctt gtatcatcgc tttcttcctt ggccagacgg 2614081 cgcaattcag gcagatactt tttcagtttg ttattcggaa ctgcctttgt gtatacttcc 2614141 actacttcca atgcatcccc ggtagccgtt gtaaagcctg cccgtccgca tgtatagcct 2614201 cgcccgtcat ccaatcgctc tacatatcca tattggatct ccgttgtgcc gttttcaaag 2614261 atacttgtca gctgttccgc ccggcgcttt tgatctttat tcagtcccgc cgcaaaaacc 2614321 gtttcgctca tcatcagggt aaaaaacatg gtgaaaacaa gtaatgagat cgctgctttt 2614381 ttccaaaaat ctgctttttg catactgatt ttcatttcac ttcccctttc taaatattgt 2614441 aaatacagac tcagtataca tgaagaaact gccctattgt tgaaaataca tcaatttgtc 2614501 aatattttga atctaaagta atatagcttg aatcttactc tattcattgc caatcagcct 2614561 tagcccctct cactgggaag gtcccttgat tttcatactg cttcaacttt cattaacaag 2614621 atgccataag gctttactct attttataat ggaagtgatc atcgaaaatc gttagggagg 2614681 tgatgtaatg gcaagcaaga tgagaatgcc agattccgca acgtcccatg caaagcctac 2614741 tattgggaag gcgatacttt gcatggggta gactttctaa aagatcgccc aagtaagctt 2614801 ttctgatata gtggctttgc accttatttg acataaaaaa ataaggagct ggcagaaatg 2614861 gcatatgtaa aagcaaccgc tattttacct gaaaagctga tatcggaaat tcaaaagtat 2614921 gttcaaggaa aaacaatata tatccctaaa cctgaatcct ctcatcaaaa atggggtgcg 2614981 tgttcaggaa caagaaagct gatcgatgac agaaacgctt ctattaaaaa agcatttaaa 2615041 aacggcaaaa ccattcatca attatctgat gaatatcacc tctctattga aacaataaaa 2615101 aaaattgtct actctaaata aacaaaacgg aagcactgat aaaaaataat cagtgctttt 2615161 tatatggcga gtttgtttct tagttatttc ctgcatatga taccattggc caattgtgta 2615221 aagttaaggg agatgagaag aaaggaaggt cctacaaatg acgataaaca atggaacgtt 2615281 gcaagtaccc ggcgcgaaca tccactatca ggtgcgtggc tctggtccaa tcattctttt 2615341 ggtccacgga ggaggcggtg atgccgacaa gttccatcat gttgccaatc atctggctaa 2615401 ctggtacacg gttgttactt atgatcgccg cggccattcc cgcagcaatc tcgccaatca 2615461 gattgagggt taccgtgtgg aaacacacag tgacgatgct caccgtcttc tagccaaaat 2615521 caccaataag ccggcctatg tatttggaag cagctccggg gctgttatcg ggcttgatct 2615581 gtgcatacgc catcccgaac aagtacatgt catgatccca cacgaaccaa tcttattgca 2615641 gcttctgcat ggaaatgagc tgaaacaagc cgagcaattc atggaagacc ttaagaaaaa 2615701 tcatcgaagt gaagtcatta aattaatgtc aagattagag acagacgaac aatcaaaggc 2615761 tgtcctgaca aagcggcttc tcggcaattc aacgtatttc actgagtatg aaattcaagg 2615821 aattctcagc tatacattag atttcgaagc attaaaaact gtgtttacat cttcaccgat 2615881 gaagatactc ccagctggcg gaagtgcttc tcgggagctt tttccttatc gttgcgcgaa 2615941 cgccctagcg gaacaattgg aaacagaatg ggttgaattc cccggaaatc atacggggta 2616001 cacaatgtac cataaagaat tttctgagag gttacacgac atgttagaaa aagaaaagaa 2616061 acatacgtgt taaggattga ttaaaatttt caaaatagga caggtgaaac taactatgga 2616121 attggagaag atttcacgaa gcgtaaaaag aacttttcac taacgagaac gcaatgtgag 2616181 atgtttaacc aaagtgatat tagggatttc atcgaaaaat aggtttgtac attacgttct 2616241 cctattgatt atttcctatc ttaattccgt attttatacc attagataca actctaaagc 2616301 ggctcgttat tttgtcctca acaacaacca gtgtctaaca tcatgaatct cttttgaaaa 2616361 tcaccacaaa tgcaggtatg gaagacttca tcgcagcaaa aaccatacca actattgttg 2616421 ttggtatggt tcgtcctaga taggccctta agaagagatt ctattgtacg gagtatttag 2616481 ctaattgcat ttgtaaccga cagggccgtc tgaacctgtg tacacatatg tgtcagacac 2616541 atatccaata ttcacgacac cccgggaatc tttccactgg atttggtccc agatattact 2616601 cgttccatac ttccctgtaa cagtcgttcc ataagcgtaa caataataag gaacacggga 2616661 gccactcgga atggaaagca taataggata atttgtacca ggaccgctgc gcatattgac 2616721 aggcgcaccg ctgcttgttg agacagtaaa gtactgaacg gcaagtgcct gactggaaaa 2616781 aatgaataaa gatgcaatca tcacggttaa catactcagc attttcagtt tagtcaatgt 2616841 catccctctt tcttcaattc cttcatttta agaaacgata gaacataggc taccagctgc 2616901 atttaggaac aaccggaccg tctgagcctg tatacatata tgtatcagag acaaatccag 2616961 gaacgatctc cccgctggca agcgtccgct ctgtgtaatt ccaaatattg ctcgttccat 2617021 actttccagt tacagttgta ccggttttgt agcaatagat cgggatgcgg gttccgctcg 2617081 gaatggtcgt tacaattccc caacttgtac ctgggccgct gcgcatgttg acaggagcac 2617141 cgctgcttgt tgaaaccgta taatactgag ccgcaagtgc atggctagaa aaaatgaaca 2617201 cagatgcaat catcaccgtt agcatactta gcctctttaa cttattcacc ttataccctc 2617261 cccttataaa tgccgtacgt ttgactttct tacatccagt taaggattta ctttcagata 2617321 ccatgccccc tcccctccca tatatttatc aatgtaccat aaactagatc tttcaaaagt 2617381 ggaattattc ctatgttttc gacaattaag gatacaaaat aaatggtagt caggcttgat 2617441 attgatggtg tgttacattt ggctcttaat catttgtcca gtcggtaatc acgattgaca 2617501 atcaggaaaa aggacatgga tcaagcggct tcgtttccac caattaactc aatcagtgta 2617561 ctgcttcctt gtatccacgc ttcttctcga ttcatagata ctccaccttt ttcaccaatc 2617621 aaaaacggac accatacaaa tcagcgtaaa tgctgcaagt tcagtgtccg caacctatta 2617681 tgactttgct ttcttttacc agggcgtgta aaaatgatta ggtacgttat caaacgttat 2617741 tctatgattt tgcgagtcaa aaaatcataa cattttatat atttcaatca gattatgatc 2617801 tggatctctg aagtgagcaa ctcgggcact ccattccttg cgatcatgcg gtttattctc 2617861 acatttaact cctttttcgt gtaaatcgtc atacgtttta tcaacatctt ctaccttaaa 2617921 ctgaagcaaa aattttgatt gagcttctcc ttccaaggac tttttttcct ctccaacgat 2617981 ttcagccatc gtttctcgag ataaaagctc tattttcgtt tccccattat caaagagtgc 2618041 atattccatt tcattctcta accaacttat tggaagtcct aatgaatctt tataaaactc 2618101 gacgcttttc ttaaaatcat tcaccaacag tctaatttgt aacagcttca tatcgagtgc 2618161 ctcctataaa accatacttt tactggtcat ccaatttaat gataccaaag aaacctgaca 2618221 gcactatgtc aagtttccat acttcaccct tatttcagat ttaagtgcag tttagtccat 2618281 gtcataagaa cgagcaaaaa cagcgattct taaaacaaaa aatgataccg agtgtatttt 2618341 ctgtatgctt caacttcatt tcgggaaatg taacgttgat aaaaggaggt tacatcaata 2618401 tggatcatca aacattggca gctcatgagg ctgttgactt acatgaaatc gtgaacttta 2618461 aaacactttg tatagcgaaa tcaaagttaa tgcaagggct tgtgtttgac caagaactga 2618521 aggacttgat ggaaaaagat gtacagcaat ccattcaaga ccttactgaa ttacaagcgg 2618581 tttatgagcg tgcctcattt caggcccctg tccctcaaag ccgcccaacg ccaatcatca 2618641 attgaaaggg aggtaagcct ctttgaataa tgatcattta gaccccatta attcgctgaa 2618701 tgtgcctgaa ctagcagaca ctacattcgc gatggatttt cttatacgag ctaaggaagg 2618761 cgtaaggaat actgctgtag ctttgacaga aaccgcttca ccagatgtaa gagcactgct 2618821 tcggaaacag ctgatgcaag gaattgcgat gcaccaagag attacggaac tgatgatcag 2618881 caaaaagtgg ttccatccat atgagctgag cgaacagtat aagctggatc agctctctgc 2618941 aaaaaacacg atcatggtcg gcaatatgaa cctctttcct gatgaaacaa atcgcaaagg 2619001 gatgtttgac cggacacctg atgaacacta acactggagg ttttacagca tgaaggcagt 2619061 aacgtatcaa ggcattaaaa atgttgttgt caaagatgtc cccgatccaa agattgaaaa 2619121 atccgatgac atgattatca aagtcaccag tacagccatt tgcggatcag atttacattt 2619181 aatccatgga ttcattccga atatgcaaga agactatgtc atcggccatg aaccgatggg 2619241 aatcgtcgaa gaagttggtt ctggggtgac taaactaaaa aagggagatc gggtaattat 2619301 tccctttaat atagcatgcg gggaatgctt tttttgtaaa aaccagctgg aaagccaatg 2619361 tgatcagtct aatgacaatg gggaaatggg tgcttatttc ggctattcag ggcaaactgg 2619421 cggttatcca ggcgggcaag ctgaatattt aagagtgccg tttgcgaatt ttacccattt 2619481 taaaatccct gaatcttgtg aggaacccga tgagaaatta agcgtgattg ccgatgccat 2619541 gaccaccggc ttttggagtg tggataatgc cggcgtaaaa aaaggcgata cagttatcgt 2619601 tctcggctgc ggaccagtcg gcctgtttgc tcaaaagttt tgttggctaa aaggcgcaaa 2619661 acgcgtcata gcagttgact atgtaaacta tcgcttacag catgcgaaac gtacaaacaa 2619721 agtagaaatc gttaattttg aagaccatga gaatacaggg aattatttaa aggaaatcac 2619781 gaaaggcgga gcggatgtag tcattgacgc tgttgggatg gatggtaaaa tgagcgatct 2619841 cgagttcctt gccagcggct taaagcttca tggcggaacg atgagtgcat tggtcattgc 2619901 ttcccaagct gttcgcaaag gaggaaccat acaaattaca ggtgtgtatg gaggcagata 2619961 taacggtttt ccgttaggag atattatgca gcgaaacgtc aatatacgct ctggacaggc 2620021 tccagtgatc cactatatgc cgtacatgtt tgaactagta tcgacaggca aaattgatcc 2620081 gggagatgtt gtcagccatg tcctgccgct tagtgaagcc aagcatggct atgacatttt 2620141 tgattcaaaa atggatgatt gtatcaaagt tgtgttaaag ccttaaaaaa cggaggttac 2620201 agaaatggaa tacgccttac acgaagtgct tgaggttcag gaaatgactg catttaagac 2620261 actttgtttg acgaaatcta aaacaatgaa agcactggta tctgatccga agctgaaaga 2620321 aatcatgcag caagatgttg atatcaccac acgccagttg caggaatttg cctctatttt 2620381 atctaatgca aagcaagaat gaggagatga ataaatcatg aatcctatca tagaatatct 2620441 gactggcatg aatgttctaa cagaccaaat cattgctatg gacttattaa tttcagcaaa 2620501 gaacggagtc agaaattatg cgatggcagc cactgaagcc ggaacgcctg aagtaaaaga 2620561 ggtccttatc cgccatttgg aagaagcact cgatatgcac gaacaactct caagctatat 2620621 gatggaaaaa ggctggtacc atccttggaa ccctgacgaa caagtcaagc tgaatttaaa 2620681 aaatattgat acagccattc aattgccaac cctttaacat acaatgactg atttgctgag 2620741 gaacagtatt gattggccac aactgttcct cagcttcaaa atgagcactg tttgttcggg 2620801 tcctatgacc gtaaatagat taaccgcttt tctccatctg atctccgata atgtttgcaa 2620861 attctccaat ccaaataagg aatcgtaacc acctcttttt atgcgatctc ttgatggaga 2620921 aaacaggcca gaaacaaaat ccttcgtttt tgacctgccc tcttcacacg caaagaatgc 2620981 taccttcttt gctccactga tccgtgaaga ctttccgttt taggcctgct tttgagcttt 2621041 gcctcatttt cacgcaattt cccatcataa tctttaattt ttgtgtctaa tctcttaatt 2621101 gtttcatcaa tttctttccg cttctctatc agccgctgtc gttcgtcagc caggatattt 2621161 tttcgagctt ctaccgtacg gtcaccttcg gtaaataatg ttgtatattc aattagcgct 2621221 tctatcgata gtcccgcatt tcgcatgcat ttaatgaatt caatccattt gatatcttct 2621281 tcatcatagt cgcgaatgcc gctgtctttt cgttttacag gcgggattaa tcctacacgt 2621341 tcgtaatatc ggagtgttgc ggctgtcagg ccaaactgct ttgccacctg agcaatattc 2621401 atgatcttca cctctctatc ctgtatgttg tgaaggtaac acttaaagtt aactttaagt 2621461 caagctcaaa acaagtggtt agctgctgaa tctgggttta tatattcggg acttgcctta 2621521 aagcacactt taaactctat acttctccat gcactaaaaa cagtgtagtt ggagggattg 2621581 ctgaatggca aataaacaca ctgccggaag agaacaatta ggagaatttg cgccaaagtt 2621641 tgctgaactt catgatgatg ttctattcgg tgacatttgg gcaagagaag aagaactttc 2621701 atcccgggat cgcagcatga ttacagtttc tgcattaatt actgactgtt tctcagctta 2621761 taaatcaggt tcattttaaa tggttttttt aaaaaaccct tgccttaaag cagactttaa 2621821 ggtttatcgt tatgttgaag acaccataaa acataaataa gtgcatgttt ttatttacaa 2621881 cacttatgat gaagaaagga taggttcgta tgtgtaatca acatcaaacc cgtgtattaa 2621941 gcgtgtcaca tgcaaaagcc aaatttgaac aaacgacgat tgagcgaaga ggattacggc 2622001 cgcacgatgt cttaatcgat attaaattca gcggcatttg ccattcagac attcatagcg 2622061 cttttgatga atggggcggt ggcatcttcc caatggtgcc tggacatgaa atagccggtg 2622121 ttgtaacagc cgttggaaca aaagtcacca agttggctgt cggggaccgc gttggtgtcg 2622181 gctgttttgt tgactcttgc ggagaatgcg aatactgtct caacgcagag gaacaattct 2622241 gcacgaaggg tgttgttcaa acgtataact cagtagacta cgacggaaac cccacttatg 2622301 gcgggtacag ccaaaaaatc gttgtcactg acagatttgt tgttcgcata ccagatcgtt 2622361 tggaaatgga tgttgccagt ccgctgttgt gtgcaggtat cacaacgtat tccccgctga 2622421 aacactggaa tgttggccct ggtaaaaagg ttgcgattgt aggcgtaggt ggccttggac 2622481 atttggcaat tcaatttgca catgcgatgg gtgcagaagt aaccgtcctg agccgttcca 2622541 tgaataagaa agaggaagct ctggaactcg gtgcaaatca ttactttgca acaagtgacc 2622601 cagccacatt cactgcattg gccgggcgtt ttgacgtgat cttaaatacg gtatcggcaa 2622661 atctcgatgt agatgcctat ttatcaatgc ttcgtataga cgggacactt gtaagcgttg 2622721 gagctcctgc caagccggac acatacagtg tgttttccct aatcatgggg cgccgcagca 2622781 ttgcaggttc tctagtcggc ggaattcaag aaactcaaga gatgctggat ttcgcagctg 2622841 agcatggcat cgaacctaaa atcgaagtca tcggagctga ccaagtggac gaggcatacg 2622901 aacgtatcct ccgaagcgat gtccgttatc gatttgtgat tgatatttcc acattgtaat 2622961 aggttagtcc ttatatgggc tgccgctttt attgaaactc acgaaaaatg atctctttaa 2623021 gcaaatattt tgaaggccgg tcaatcttcc tgttattcta tgaatagaga gttattagga 2623081 gggtttttta tgagcaaaaa aattgcagtt cttgttacag accaattcga agacatcgaa 2623141 tatacaagtc cggtaaaagc atacgaagaa gctggctaca gtgttgtggc tatcgatttg 2623201 gaagccggca aagaagttac cggtaagcat ggcgagaaag taaagattga caaagccatc 2623261 tctgatgtgg atgcaagtga ctttgatgca cttttaattc ctgggggatt ctctccggat 2623321 ttgcttcgtg cagatgaccg tccgggtgaa ttcgcaaaag catttgtcga aaacaaaaaa 2623381 cctgttttcg caatttgcca cggcccgcaa gtactgattg atacggatct tctaaaaggc 2623441 aaagatatca caggctaccg cagcatccgc aaagatttaa tcaatgccgg tgcaaactac 2623501 aaagatgcag aagtagtcgt cagccacaac attgtcacaa gcagaacacc tgatgatttg 2623561 gaagcattta accgcgaatc tttaaacttg ttaaaataac aagaaggcac agactgttcg 2623621 ggtctgtgcc ttttttaaaa ttaagactcc ttcgttacat tctgaaagac agcagtcgcg 2623681 tcccacacat tcaagccaaa ttggccttct gaaaatacgg aatcatgtgc atcaatcaca 2623741 agacgatcat ctaaatagat tttaaagcga tcgccctcgg cctctgtttt cagatgatac 2623801 tttttattaa cgtctatcgg tgttttgtat tcagcaatga cagaagcagc accgttctca 2623861 aatttaaaga atttcactag gtcatgcttc gcatccacat tggcaaggta accgtttttg 2623921 gcatctttgt cagagcgaaa cattagtgct cctgcccctc ttccgtttcc atccttaatg 2623981 gtgatatcag attcataagt gaagtctgac ccggatgctg aagacaagat aaaggaatcg 2624041 ccgtccgacc tcccttgttt cccctcaatt gtgtctgccc acgtgccatt tacagtcgtc 2624101 cagccagtca tattggacat aaaaggtgtc gttccccata ccttttttaa agggtgtatc 2624161 gttaaagatt ttacctttac accgccattt gcagcatata attcaagccc tttgcttgat 2624221 cggtctggga gaataatatc cgttatgacc tgctttccgt cattcccaaa tacttcaacc 2624281 gaggagcggt caacaaaaat gcgcaactta accttcccat ttaccggctt caacggggct 2624341 gtttcttttc cggtgttaaa ggccggatta aaggtgtcgt tgcctgactc gctccggtca 2624401 acgaacaatt tggcgttcct tcggtcatag ccgaccttcg taaattgatt ttcacctgtt 2624461 cggaccttaa aaccaaattc agcagctgaa ccagggctta ctttaaattc tgcatttatt 2624521 tcataggcat ctccagattg ccccgctaac acattatgac ttgcaggcga tatggtcaga 2624581 ttcttccact tcttagaggt tccgcgaatg gtttccagct ctttcaccgg tgtttggacc 2624641 actctaaccc cttcggtaaa cgctttcaat tttaactctc ttggaatgga cgttgcactt 2624701 ctccatgggg atgtcggaac atcattcgca tattgccaat tgctcatcca ccctaaccat 2624761 agccggcggc tgtctgtgga tggaatatca gaccaggata cagccgcata aaagtctctg 2624821 ccgtaatccg tccagagaac tttgtttggc gggttttcat ttttaaaatg agttccatca 2624881 aagtccccta caaaatattg catgcctgat cctcccgaga ccgctccgtt tccgacactg 2624941 acctgcatga cccatttctt ttgattcgga ttgccgtcta ccggaagctc aaataaatcc 2625001 gggcattccc atactccccc gtggcttcct tgatcctgtc caaattcact tgcatacgtc 2625061 cactgcttca gattttttga tgtataaatg aggattcggt caccggccgc aagcaccatc 2625121 acccactttt tttctttctc ataccaaaag acttttggat cgcgaaaatc ttttttaccc 2625181 gggtttggaa tgacagggtt gccagcgtac ttcgtccatg ttcttccttt gtcgttgcta 2625241 taggcaatac tttgcacttg atggccttcc cgatcctgtg tataaatggc cacaagcggc 2625301 ttctctttgc ctgtttgaaa accgcttgtg ttatttttat ctacaactgc gcttccagaa 2625361 aagatcgtgc ctttttcatc cggatacagc gcaacaggaa ggtgttccca tgtaaccaaa 2625421 tctttgctga cggcatgccc ccaatgcatg ggcccccact gaagcccgta tggatggtat 2625481 tgatagaaca agtgatattc cccagcataa tataccattc cgtttgggtc attcatccag 2625541 tttgcctccg gtgtgaagtg atattgagga cggtaatcct catcatagta gcttgaatcg 2625601 gctgcatctg ccgaaaatgc catagtcaac agcagggtga acatgatcat gacttgaatc 2625661 agtctctttt tcatttgttc cttcgctcct ctcttcatgt ttgaacactt tcaaaagaga 2625721 ctgctgcgca agctggtccg tttctggcaa ttctcctctg tttcactgtt atccgaatga 2625781 tttatatatg aaaagactgc tgcagtttct ctctctttcc ttcacacacc ttatgctaag 2625841 aatccagccc aatacccgag aatcccgatg acaaagatgc cgcaaataat gagaagtgga 2625901 ttcacccctt tgcgaagcat ccatgccacc aataacgtta atccgagagg cagcgccccc 2625961 ggcataatgc tatctagcac gttttgtacc gtttgaacat ctacttttcc gctttcatcc 2626021 ttaatcctgg atacaacgat tggaatgttg atggtggtcc atttggacac gagagccccc 2626081 ataacaaata acccgagaat cgaagcgccc tctgtaagct tttgaatgcg attccccgct 2626141 aaatcctgaa gaatctccat tcctttcaca tagccatact ttaatccgta atattttgtg 2626201 cttaatctta tggcattcag caagaaaaag aatagcaaag gaccggcaat gtttcctcct 2626261 aaagcaaggg aggctcctag cgcagctaag acaggacgaa tcgttcccca aaaaattgga 2626321 tcgcctacgc ccgctattgg tcccatcaaa ccgattttca ttccgcttat cgcttttccg 2626381 tcaattcctt tattgttcgc catttcttct tccatggctg ccgtcacgcc aaatataggc 2626441 gctgtcagcc acggatgtgt attaaaccat tccaaatgcc gctgtaaggc ttcgtttctt 2626501 ttcgctccgg gaccgtacaa ttttttgatc gccggtatca tgacataaca atatcccatt 2626561 gcctgcacac gttcgaagtt aaaggaaccg agtaaaaaat ttgaacgaat aaacatgctg 2626621 aaaatttctt tcttcgttaa tcgtttttct ttctccattt tttcttcccc ctcatcgttt 2626681 aggcatcaag atcatcatca tcgtcatcat aaacagcaac actgccactg tctgatgcgg 2626741 ccgcgactgc tccgtgagcg ctttgttttt gcatcacctg ctggtataaa agcgccagac 2626801 agagaccaag ggctccaaat cccactaagt taaaatcggt aaacgccgct aataagaaac 2626861 caatatagaa aaatggcttt aaataaggaa tattcatcat attgatcacc atggcatacc 2626921 cgacaaccac aataatgcct ccgcctattt gcagtccttt tgtaatgaca tcaggaatat 2626981 ttcccaggaa cgcctgaaca gcgctgacac taattaaagc aacaatcaat gtaggaatca 2627041 tgacgcgcaa agcttgaaac accatcgcgg taatatgcat aatttcaatt ccttttatat 2627101 ttcccgcttt tgcatattga tcagcgcggt ggatgaaaaa gacagtgatc gtccgaacaa 2627161 aaatcgtcag cgcctgaccc gcagctgcta aagcaacagc gacagcaatc ccttcgccaa 2627221 ttccttgatc agcggtaata actaaaatgg ttgagatgac agaggcgatc gctgtatcag 2627281 gtgccatggc aagcccgacg ttcatccagc cgagcgccat cagctccagt gtgcctccaa 2627341 gaataattcc cgtttttaag tccccgagca ccaagccaac caacgtacag gccactagcg 2627401 gccggtgtgt ctgcccttca tccaatacac ttgcgattcc ggtgattgct gcaatgatta 2627461 acaacaaaat aatttgtaat gaagacatat tctcatcccc ttgattattt tgttacgttc 2627521 cgtaaaatct gtacaaaatc ctcactggca tctgaaggca gctgcctcaa ttccagtttc 2627581 acgcccttgt cacttaatgt ttcaaatgcc tttatatctt gttctgtgac actgactgat 2627641 tttgtgattt gcctgcgatg attttcaaaa cgcattcccc cgacgtttac ggttttgatc 2627701 ggtacacctg cttctataag agatacaata tcggacggat tttcaaacaa gagcattgcc 2627761 gttacccctt cgtagcgcgg actatgaaat gcttttgcca ttttagaaac cgagacggca 2627821 ctcgccttta catttgaagg cgcaacagaa aggatcagcg tttttctcat ttcgtcctga 2627881 gcaatatcgt cggagacaac gatgattcgg tcggctgcat ggacttttat ccaccttgtc 2627941 aggatttggc cgtgaataaa gcggtcatca attcttgcta acacaatgtt catcataatt 2628001 catcctctct tgtatcttga ttggctgttt ttactttttc taaatgttca ctgcacactt 2628061 gaaagctttg ctgactcatt gcttttaagt tgttcagcaa atctttgaga gccagatgtt 2628121 ctctcaggct taatacctcc agcagaatcg gcaggtttac gccggcagcc atatccattc 2628181 tttgatcctc agcaataaag gaagctgccg cgttatatgg cgtccctcca aaaatatcga 2628241 ctaaaaaaag cacttcatgt tcttccggga tatccttgag cgcctgatga tatttttctt 2628301 gcagcgtttg tattccttcc cctttgaaaa acggcactgc aatcaggtta ttttcttcac 2628361 cgaatatcat ccctgaagac tcttttaatg ctatgggaaa atctccatga ccgctgataa 2628421 taactgaaat catatctatt gctcctttcc tgttttgtac atccatatat aatgcaagga 2628481 tcgtgccaac acagttgtgt taagcgtttt cattgttatt tcagccaata gcaatttgtt 2628541 gttgaaacac ttaaaacgaa aaaaataaac ctgtattaaa atggtgttcc atttaataca 2628601 ggttcatatg aaaaaactgt ttttaaaaca gctggccatg cacttcttca gcaaatatgg 2628661 cggctataaa taatttttca tcatcactta tgcgaagtcc gagcttttct tcataagggg 2628721 ctaatgttcg ctctgtcacg tacaccattt ccttcagctg atcattgatc tcttcttcct 2628781 ctgagaaagc gatcggattc tgcttaatta ccctttcaaa ggcgaaagcc gtgtgcataa 2628841 tgactttgat caaaaccgca ttattgaaaa tgacccccag ctcatcctga acggtttgca 2628901 gccactccaa taacatgtcg atcacatggt ggggattcaa gaagacaagg tattttttca 2628961 ggctatcctc gcaaagctcc ctgacaataa tatttgcttc gttcaatcca ttgctcaagg 2629021 agatgcttcc ttttgtaatc gcctgttgaa tcagcttctc tccctcccct tcaattaaca 2629081 cttctaaaga tacatgcgga gcattgattt tagggtcttt cgttccgact gtcgcaagga 2629141 tttcatactc tttttcgatt tcttttatgc tgttggccag cttaatcgat gatacggtca 2629201 atatgtgaat gggggtatcg gaggccttgt ttacgatcgt ggttagaatg tcttccagct 2629261 ttttggccgt tccgctaccc gtcgtgcaga tggataccaa tgccttcttt ttgccggatg 2629321 ccgctggctg acgctcccac aactcgataa aatccttcgt gaccgattga tagatcgcat 2629381 gcaaatttaa attcaaatag ttgacctttc tgacagcatc cagcaccatt gaagtcgtaa 2629441 cattgctgat cgttttaata gaaatgcctg tcttttcctc cagcctgctt tccagcattg 2629501 caagcgaccc catatctacc agcattaaaa caccttcacc ttcatcaacc tgtttcattt 2629561 tttctgctac gcattcaaga atgtccgaag gtgaaacagt aagcggcatg tcaactgctg 2629621 caatcggcgt actccctagc agttctgtcg cgacttcaac cattgaactc gccgtgctgt 2629681 ttccatgagc tgccacgata ataccgactc ttttgttctc ctttaacgat ttgatggaat 2629741 gaattaacat cgttaagtag atgacttcta tttcaggaat agccacttta aaatattcct 2629801 gaattttatc tttaaaaatc atcgccaccc gatattcttt cacatgggta tcacgaattt 2629861 catctgtctc ctgtgtattc aaaacatcaa tttgctttcc tcgctttaaa aatgcgtcaa 2629921 tatgcatact caagaaataa ataaacttac ggtcaaatgt gcaatccagc tcatgttcag 2629981 ctatttcttt taactgtttt gtcatttgaa tcacatcgtc ttcaacgaat gtcagcaggt 2630041 tgtctttttg aaaagcttga tgatgaaaaa aacttctgac atgcaaatgg acatcagtca 2630101 agatgtactg gttaatatcc tttttggata aaccttcttt cataagcgtt ttcacttttt 2630161 cctcaatcaa atgatataag ttaaatgaga ggtcttcgtc aatttttgtt gtttcatctt 2630221 ctacaatcgg agagataatc gttgtaatat tgacatattc agaaatggct ttgcttcttt 2630281 gcatgttttt gctgctggac atccattctt gcttgatttc atcaggcaga tcgcgaacag 2630341 tcagttcaat aacttcattt ctgtcaaggt tatgcaaaaa tccgtgtgcg caaactaact 2630401 gaacatttga tttcagctgt ccgacattcc caaatttcgc agagtgaata agcgcattat 2630461 agacatcgat atgcacactc agattcttct taattcgctc tgcttctttc cctaataaaa 2630521 acgtcgtcag atccactctt tcattaagcg atcgttcttc aagcgaagga atatgaatgg 2630581 tcattgggat tcttcgcaaa aacgttttca atagtgcaga actcggattt tctgtagtcg 2630641 cacaaataaa caatacgttc gatgttcgtt tatgttcaga ttctccaagc ctgttataag 2630701 aaccgctgtc aataaaataa aacagcattt cttgtccctc gggagggaga cggtggattt 2630761 catccataaa aagaatgccc ccattggcct gttcgactaa acccgcctta tcctcggcag 2630821 cacctgtaaa tgaacctttt ttgtgtccga ataattgaga aagcaataat tgagggttgt 2630881 tgtagtagtc tgcacagtta aatgtaataa atggtgcgcc ggccttcaat atgtcagagt 2630941 aaatggcaaa ctggtaaatt cggttcgcaa aaagggattt accggaacca gtcggcccta 2631001 ggaggagcat atgcagaccg ttcggcggat aaaagacagc tgcttttgcc tgggagatcg 2631061 ctttcttcaa actccctttt gcccctatca taagctctag gggattcgtg gaaatgtgtt 2631121 gatgattttg ctttgaattt ccggaaaacg cctgaaggtc tttcacttcc atcatctctg 2631181 tatcccattt cttgttgaat aatttttctg ctatctcgac tgggatgtat cttacaggaa 2631241 atgttttaat tttgatgacc tttttggacc ggacgagatt gttcaattca aagctgacat 2631301 tggaccgctc cattttcagc tgctcggcaa tctcctttgc tgaattccct tgtattttta 2631361 aaagatgatc taaggttgaa tcatgaaaat tatgcttgag ctgatggtat attttatcta 2631421 ttcttctcac gtctatcatc ctttgtcctt attagataag ccattaacaa gaatatttcg 2631481 aaactttata gtccgcgttg agatttacac gtttaaaaag gtctctatag cagattgaca 2631541 aagctggctt ttatgcgtat atgtttacat gttgaatcat ttgcacctca tattagtatg 2631601 atagatgctc agttctggag ggccagtccc cttcaaaagt aataatcagt aaacagttta 2631661 tcattctcgg ggaatgtaat gatgtcaaaa taatcaatga caaaaaatga atcttataga 2631721 tcatgacaaa ttacccaaat ataacccctt aagttcgttc acaactaaaa agacggacac 2631781 tctatgtgac cgccacagta ttacaatttg caaaacttcg tcatttttgc aatccacatt 2631841 ggaggttaag gaatctgtaa gcttaaaaac tttatctccg atcctatcga tttgatcccc 2631901 ctgccggcct caatcatagt gggtatgcaa ttatacaaat cgttaccgat taaaactagc 2631961 ctgtcagatt gtccaaatga ctttcctgtt ttactctgct attcaggtag aatcacgagt 2632021 gaaaaataga gccacaagac atgtaacagc acttaaaata gttttaaaat ttaaaaataa 2632081 aagtatctat tcttttaaat gttataatat ccgataaaac tttactcatc tttttattac 2632141 tggaggaaaa taaaattgat aggcaattct agcaaagaca attttggcca gcaacagaaa 2632201 ttgtctagag gccttaaaaa caggcatata caattaatgg cgattggagg tgcaatcggt 2632261 acaggtttat ttttaggttc aggtaaatcc atccattttg caggaccatc cattttattt 2632321 gcttacttga tcaccggcgt attttgcttt ttcattatgc gttcgctcgg agaactgctc 2632381 ttatcaaatg cgggatacca ctcttttgtt gattttgtaa gggactattt aggaaacatg 2632441 gcagcattta tcactgggtg gacctactgg ttctgttgga tttccctcgc gatggctgat 2632501 ttaacggcgg tcggcattta tacgcaatat tggcttcccg atgtgcctca atggctgccg 2632561 ggtcttcttg cgcttattat cctgctgatc atgaaccttg ccaccgttaa acttttcgga 2632621 gaattagaat tttggtttgc attgatcaaa gtcattgcca tactggctct gatcgtaact 2632681 ggtattctcc tgattgcgaa aggtttttcc gcagcttccg gccctgccag cctcaacaac 2632741 ctttggagcc acggcggcat gttcccaaat ggatggcatg ggtttatcct atctttccaa 2632801 atggtcgtct tcgctttcgt gggtattgaa cttgttggac tgacagcagg tgaaacagaa 2632861 aatccccaaa aagtgatccc taaagccatc aatcaaattc ctgtccggat tttacttttt 2632921 tatgttggcg cacttttcgt gattatgtgt atctatcctt ggaatgtgtt gaatccaaac 2632981 gaaagcccat ttgttcaggt cttctctgca gtaggcatcg ttgtggctgc cagtttgatc 2633041 aattttgttg tattaacatc agccgcatca gctgcaaata gcgctttatt cagcacaagc 2633101 cgaatggtct attcacttgc aaaggatcat cacgcacctg gactattaaa gaaattaact 2633161 tcttctaacg tgccaagcaa tgcgctgttc ttttcatcca tcgccattct gattggcgtt 2633221 agtctgaatt atttaatgcc cgagcaagtc ttcacgctga ttacaagtgt ttcaacaata 2633281 tgcttcattt ttatttgggg catcacggtg atttgccatt tgaaatatcg aaaaacaagg 2633341 cagcatgaag cgaaagcaaa caaatttaaa atgccttttt acccattatc caactattta 2633401 acacttgcat ttctcgcgtt cattcttgtc atattggcac tggcgaatga tacacgtatt 2633461 gctttgtttg tcaccccggt ctggtttgtt ttattgatta ttttgtataa ggtgcaaacc 2633521 cgcagaggac ataaggtgaa ataaaaaaaa gacaagggat actcactccc ttgtcttttt 2633581 atatgtgtca aacactaaat taaactttgg tttcaaattt cattcacttc atttaagtgt 2633641 taactcaaac cagttttgat gccgaaacct actaatatta ttccggtaat tttttgaaac 2633701 actttctgga acttcgagtt tttcatccat ttttttgcgt aatcaataat ataaacaaga 2633761 aacaggaacc acaacaccgc taataaggtt aggattgaag ctaaaatgat gagctgctgg 2633821 tttatatttc cgttcaaatt gataaattgg ggcatgattg taacatacac caaaacagtt 2633881 ttaggattga gaatgttact gagtgatccc tgcataaagg aagttttata ataacgtttc 2633941 ggagaacttg ccatattttt tgcttgggat tgcatgtcat ctaacgaaaa catactttta 2634001 gcaaaaaaac tttttacacc taaataaatt aagtatgccg ctcccaaata tttgatcgtt 2634061 gtgaaaagaa tcactgactt tgcgattacc actgataatc ctaaaatggc aatcaccgtc 2634121 caaaaggaaa gtcctgtcgc caatccgaga atgttataac ggccggcttt cggaccatac 2634181 ctaagcgtat ttttcatcac aagcatcgta tctgcccccg gtatgataac catcatggca 2634241 gcgatcggta tgtatgcgag taagctgtgc attgttctct ccccctttaa aaatcccctc 2634301 aatcatatag tgactacaaa agtaactact tataaaagtg tatcaatgcg tttggaataa 2634361 atcaatatga tttgttaaaa tagcgattac taaggcagcg attgctcttt atattggagg 2634421 atatatgaaa gaaaatatgt tagacatttt aaaaaacctc aattttacag aatatgaatc 2634481 gaaagcgtat ttagcattat tgcaagaatc acctttaaca ggctatgccg ttgccaaaaa 2634541 atccggagtg ccccgttcta aaatttatga agtattggaa agtcttgtca taaggggaga 2634601 tgtttttgtc agtcatggaa atacgcctca gtatgttcca gtccccgcaa aagaactgat 2634661 taaaaaccgc cggctcaaag cggaagagca ttttgatcag gctgagaaat attttgaaaa 2634721 gttcgagcag accgcaaatg accgggaaaa catctggaat atcaccggcc gcagtgaaat 2634781 tcttgaaaag gtgaaggctt gtatcttatc tgccaaaaaa agaatcctct tagaaatatg 2634841 gaaagaggat tttaaggaga tagaagcaga gctcaaacag gcggcagaac aaggcgttat 2634901 tgtcaccatt attgcgtacg gagacatcgt atctgatttt gccaatgttt accttcatga 2634961 tatgagcagt gaaattacag aagagtatga cggacggtgg cttgtctata gcggagatga 2635021 ttcagaagta gtagcgggca ttgtctcact tggcaacgac agccgtgctg catggacgat 2635081 gcatgtaggg ttagtcatgc ctattactga agtgatcatt catgatctgt acctcatgga 2635141 aattctgaaa aagcatagag agcttttaga agagagcttc gggaaaaatc tcatccagtt 2635201 gcgccgtaaa ttttctattc actcagattt caaaaaacat tatttggaat aatgtttgtc 2635261 atctcttacc ccaaaaacaa ggcttgtaca aaacaagcct tgttttttta tgcataaacc 2635321 ccccatgctg atttacttct ctcttttaaa aaatgtgatt ctgcgcaaac tatttttcag 2635381 cctgccgcgt ctatcctagg taacagccta cgatatacgt atattcaaaa aggagccctt 2635441 tattgcaatg aagaaaaaac aaacaacaaa agcgttgctt gtcacatgca taactgacca 2635501 taagcaagat ttctacaggt tggctttcag ttatgtgaaa aatcaagatg acgcattaga 2635561 tattgttcag gaatctataa aaaaagcgct gagctcagtt gaaacggtca ggaaccctga 2635621 gacgataaaa agctggtttt ataaaatttt agtacggaca gccattgact ttttgcgcaa 2635681 acaaaaaaag ataagagtga tggacgacga aacgatagaa tttttaagca aaggaaagga 2635741 agaccattac aaggatactg atctccatga agcgcttgac gaattgccgt accgctataa 2635801 aaccattatt attttacgtt tttttgaaga cctcaaatta gaagaaattg cggaaattac 2635861 aggagaaaac acgaataccg tcaaaacgcg cctatacaga gcattgaagc tgatgcgcat 2635921 tcagttgacg aaggaggatc tttcttaatg gataagagat tacagcaatt aagagaagaa 2635981 tataaaaatg ttcagattcc taaagaattg gatatcattg ttgaaaaagc ccttcagcaa 2636041 gaaccaaaaa agaaaagaat cgttatgtgg ccgacatcag cagcaatcgc tgcagctatt 2636101 ttattcactg cgcttgttaa tatcaacccg gacgccgctc aggctatgtc aaagatccct 2636161 gtcatcggca aaatcgtcaa agcgatcacc tttattgaaa tcaaagagga aaaagaccaa 2636221 tcaagcattg atgtcaaaac acctgctttg tccgggcttt ctaataaaga gcttgaaaac 2636281 agcattaacg agaaatactt gaaagaaagc cagcagctgt ataaagagtt tatacagtcc 2636341 acatccaaaa acaaaaaagg gcatctcagc atctacagtg attacgagac ggtcacagac 2636401 acgccagatt tactctctat ccggcgcaat attgaaacaa cacaagcatc ttcctacaca 2636461 caaagccgtt atattacaat tgacaaaaag aatgatattt tacttacatt aaaaagctta 2636521 ttcaaagatg agcgctatat caaagtcatc agtcaaaaca tcaaagaaca aatgaaacag 2636581 caaatgaagg aagatccaaa taaaatatat tggctcactg acgaagatgc agaaccgttc 2636641 aaaacgattc ttcctgatca gacgttttac attactgaag accataaact tgtgatctca 2636701 tttgacgaat atgaagtcgc ccccggctat atgggcgtta cagagtttac aattccaacc 2636761 ggcgtcattt caaacttgct cgtgggagaa cgttatattc gataaaataa aaacatccat 2636821 ctaagattat ggatgttttc tctcttctct attcgaggtc gtaaccccgc tatcaaaaac 2636881 aacgagaata tttgcatact attggaggaa tacccatgta tcacaagaca cagcatcatc 2636941 gatacattcc tggacttgat ggccttcggg ctttcgccgt cctgtcagtt atcacttatc 2637001 acctaaattt caattgggct aacggtggtt ttatcggggt tgatatcttt tttgttttat 2637061 ccggatattt gattacatct attctattac cggcatatgg aaatgatatc aatcttgatt 2637121 ttcgggattt ttgggtgcgc cgcattcggc ggcttctccc ggcagcgtac cttatgatct 2637181 tttccactgt tgtgtgggtc gtattgtttg atcgagaact attgcacact gtacgtggag 2637241 atgcgatctc ttctctcttt tatatgagca attggtggtt tatttttcac aagctatcat 2637301 attttgatag tttcggttcc ccatcacctc taaaaaacct ttggtcgctg gcgattgaag 2637361 aacaatttta tatcatatgg ccgatgtttt tagttgttgg aatgtacata atgaaaagcc 2637421 gcgccagatt ggctgcggtg atatcattgc ttgtgctttg ttcagccgtg atgatgagcg 2637481 tactgtatga acctggcgga gatccgagcc gcgtttacta tggcacagac actcgttcgt 2637541 ttgaacttct catcggatgt gccttggctt tggtatggcc gatgaaaagg ctgtcttcca 2637601 acaggctgcc aagcaaactg aagcacactt tgcacgccac tgaatttttg gcattttgta 2637661 ttttagtgtt gtgtgtctat ttcacagatg aatacgagcc ttttctttac agaggcggaa 2637721 tgctattcat tagcgtgact gccgcaatcc ttattgcatg tgtttgccat ccgagcagct 2637781 ttttaggcaa tctgctttca tggaggccgc ttcggtggct tggaacgagg tcttacggaa 2637841 tttatctttg gcactaccct gttattgtgt taagcacgcc agttcaagaa atcggaaacc 2637901 ctgttttttg gcatatcgtg ctaaaggtca ttgtgacatg tatacttgcc gagctctcct 2637961 accattttat tgagaagccg atacggacac agggatttag gtcattttcc cgccgtgttt 2638021 ttatacatag aatcaaggaa tggaaaacga catctgtcat cagcaaaatg tcaattggtt 2638081 tcattatttt cgctatactt atttttgcag gcgggctgtc agggctagcc ggcgagcaaa 2638141 agcaccctac caaatggacc tatagctcac aagaaacaaa tgctgacacc agccaggctt 2638201 ctggggataa aaagaacgct gcagcagata aaaaacacaa tcctgaacaa aagacaacag 2638261 attccaatca gggtcaaaag gaaaacaaag atagtgggca agagactcat aaaaagaaag 2638321 acacgcaatc ccaacagttg aaaaaaccag cagacactgc gaaagaagtt ttagctatag 2638381 gagattccgt catgcttgat atttcttcac acctgcgtca gtcattttca aatgtgacga 2638441 ttgatggaaa ggtagggaga caaatgtctc aagctttgga actcgcaagg gaatacaagt 2638501 cttttaatca gccgaacaag gctgtcatca ttgagcttgg aaccaatggc tattttacaa 2638561 acagccaaat cgaacaactg cttcaatctt tctcaaaagc tcatatttat cttgtcaata 2638621 cacgggttcc ccgccaatgg gaaagcaagg taaatgaatc tttgcagcaa caggcccacg 2638681 cacatcaaaa tgttacgtta gttgactggc atacagaagc tcttcagcat ccggaatatt 2638741 ttacccctga tggtgttcac ttggttccta aaggggcaaa aactttgact gctcttattg 2638801 ttcaggcgat gaaatcgtaa aaaagagatc ctatacagat cactttttta ctttagtttc 2638861 tgatcgttga ttatgtcttc tttcagcaag gcagccctta tgtttacatg ccgtttacgt 2638921 aagggtaagc caaaattgaa tggagggatg ataatgaaag gaaatgaaga acatgacatc 2638981 caaaaagagt tgaaacgata tgagcttttt ttcaaaaaac gatataaggt tctttataca 2639041 gtaaacgatt ttatcatcgg tgctatgttt ctcgttggaa gttttttctt tttttatgac 2639101 cggttaatgt cggcagggat atggctgttt gcgatcggaa gtttgctgct gttaatcagg 2639161 ccgaccattc ggctgattca tgactttcat taccgtaagc atgtggaaca gcaattcaag 2639221 catcaatctt caacagatga ctgatcttaa ggaataagaa agaacaaaat gccaaaagcc 2639281 tgagtcgaaa atcaaaaaca agactttcag actatttatt tttaaaaaca aggtaaaaag 2639341 aactaaactt ttgcctctgc atgccgatat gaataataag gccggcgcga tactccctat 2639401 aacatccttt tcagtagatt tcattatcgt gccggttttc tcatatgcaa agcaatcccg 2639461 ccaatcagat tggcgggatt ttatatttta cattcctgtc caaacgtctt tcacataacg 2639521 tctttgatct tgcagctttt gcagccatac agctgattct tcctgacttg ctgctttttc 2639581 agcttcatat gccaatcgca aagttctctc tacatcagga gccatttgcg atccatcacc 2639641 gcatacgtaa atatgagccc ctttttcaat gagtgtcatc aatttctgcg tatcttgctt 2639701 gagcaagtgc tggacatatc cttttggttc gttttcgacg cgcgagtagc atcggcggat 2639761 tgtgaccaaa ccgtcctgtt ccgcttgatc cagctcttct ctgtaaaggt cgtcatggtc 2639821 cgggcggcgg cagccgaagt ataaaagtgc ttcaccaagg gtgcttcctt ccttcttcaa 2639881 aaccgatctt gcctgaataa agcctctgaa tggcgcaatt cctgtgcccg gcccgaccat 2639941 aatcataggc gtttcaggat cattcggcat ctgaaatccg gactgcggcg tacgaatgaa 2640001 gcaagctgct gcatcacctg tattcaattc tgctaaataa ttagaggcga caccccggta 2640061 ttcacctcgg ccgctccatg ctgaggcttt cacaactcct accgtcatgc tcacgatatt 2640121 tgcatgaact ttcggtgagc ttgaaatgga atagtatctc ggttttagtg atggcaaaag 2640181 tgctaaaaac cgttcaaacg gcatttcgca agcaggataa tcctctaaaa aatcaagcat 2640241 ggtaagacgt tttgcaagta cctgctcttt gtaaatgcca tcatctgaaa cgagctgttc 2640301 cagctctttt tgatgcggcg gacaaactgt ataagaggcc agctcccgaa gctgaagcct 2640361 tgatgccggt tcctgcagct ctacatagga cgacaataaa tccactactt tgattggccg 2640421 atccatcggc agatgagcca tatgagcgct tccgcttact tttatcacat gattggactg 2640481 caaaccgaat cggctgagaa cccgctgaac aagctccctg ctgttctttg gcaggattcc 2640541 gatatgatcg ccttctttat atgttttacc agccggaatt tccaattcaa tatggcgggt 2640601 tgaacgcgtg ctggcagctg tctggagttc tcgattctct aacacaatcc cttcaaacgc 2640661 gccatatgct ttagcaaccg gcgtttccgt cgcttcactg agaaaagtaa tcgataatga 2640721 aggcctgtct tctttctggg ctatttcgtt aatatcaaat gcgtccatcg tttccttcca 2640781 gaagcggttt tcccaagact cgcggtggct ttcaaaatca tcggcggcgt caccttcccc 2640841 aatcgctgtt aaacgcgatg ccccctttgc tttcatcatg tcatcaatca ggcggggaat 2640901 ccgctgatac gtgctggccc agctccggtt tccgcagccg aataccgcat aggaaacacc 2640961 tttcaattgg ccttcctcaa gctctttcag ccactctaca aatccggcag cattatcagg 2641021 cggcgcccca ttataagaag ccgttacaat gacgactgcc ccttcttcag ggagcttgcc 2641081 gatataatca tcaagcggag ccgtttcagc tgtaaagccc atctggcggc cttgagcagc 2641141 cagttcaccg gctattccct cagctgtccc aagatttgaa ccaaaaagaa caagtaaagg 2641201 tgtgccgtgt ttaggtttgg tttcttttgg ctttgtttct gctttgatgt ctgcctgttc 2641261 ttttctctgt acattgattg ccgctgtttt tcgcggtttc acagtaattt taaaatcatc 2641321 cggcttgatc gttaatgctt ctttgatttt tagttcgtag ccagtatggt ttatcaattc 2641381 aaaatgcttt aatacaagac cgagaaccat tgtcgcttct tgaagagcaa actgcatgcc 2641441 aatacaagcg cgctgtccgt ttccaaacgg cttatacgca tggtgaggga tacttgaagg 2641501 atcctcaaac cgttccggac ggaaatcttc cgcatccggt ccccaagcgt tttgatcccg 2641561 gtgcagtttt ggaattaaaa cagtgactgg ctgccctttg ctgatcggat attccccgcc 2641621 tagaacagta tcctccttcg catatagaga aaaagccgga gctgttggat acagtctgag 2641681 ggtttcattt aaaaccatcc gaatgtattt gagctgctgg atttgtttat attcaggcgt 2641741 gtcatccgtt aacacgcgat ccgcttcctc ctgagctttt ttcagttttt ccggatgtgt 2641801 aagcagacaa taaatcgcaa aggatagcaa cccgcttgtt gtctcatgtc cagcaattaa 2641861 aaatgtgatg atttggtatc gaatgttttc gtcatccagc gtttcacccg ttactggatc 2641921 tttggcataa agcatgagag acaagagatc cttaatgttt tcatccggat tcgcctttcg 2641981 ctccgctatc attctatcaa ccagggagtt catgacttct atatcctttt ggaactgcag 2642041 cttcgttttc accatcattt tatcttgcag gcccagtctt ttcgattgat tcatcgcctc 2642101 ttttaaggca cggagcatac tggtgataaa cggatgctgt gaatcacggt aaaagctgtt 2642161 gaatcgatag ttaaacccgc ataacccaat cgtatcaagc gtcagacgtg tcatatcgtc 2642221 cgctacatca atttcttcat tagggtttaa ccggctccac ttttgaatca gctgggttgc 2642281 gatatccagc atcatagaat gatagccttt catcgctttt tgactaaaac tcggcagcaa 2642341 aatgcggtgg gctttttgcc agttcggttc gtgcgtccag cttgtaaata agccatctcc 2642401 cccgaactca cgcacctttt gcaagccttt gccaaggttc ttgtcaaagc gtttttcatc 2642461 acacacttca gccacaagat tgtggccgga cacaaaaaca ctggatactc ccggaaaatc 2642521 aaaacggaaa atcggtccca attcatcagc tatccgccat aaggattgag aaagctgttc 2642581 tttttccaga tgcggaagat tttttaaagg tccgtatgtt ttgggctgag gtattgcgct 2642641 tgcctgtttc attaacatct ccctttccta tttttgtgat gaatgaagct taatggcgtc 2642701 ccagcagcat tgttccaatt cagtaattaa atcagtgtcc atctctatat cacctgtttg 2642761 aacgagctga tatatcttga gaaacgcccc taatacaatc gcaattaaca cattagaggg 2642821 caggctgcga atcacgcctt ccgcttttcc cttattaaaa tagtcatcaa gcatttgagt 2642881 cagattttct atcatttttt tgcttgtatg atttaagtaa tgagcgtctt ttttggtttc 2642941 aagaaaaaaa agcgcatagt cgctctcttt cgtaaactga acgagacagc aaaatacgtg 2643001 gtgaaagcct tctctgacag gcaattctga aacgtcttgc ttcagttttt ccgtaaatcg 2643061 ctggatgctt tcttgaaaca gtacgttaac gagtgtttct ttgctgtcaa aataacgata 2643121 gatcgttcct gtccctacat gagcacgttc agctatcata ggaatagtgg tagcgtcaaa 2643181 acccctttcc gtaaaaagtg agactgacgc tttcataatc atgtcgtatt tactgctgga 2643241 tgcggatatc atgtaatctg acaacctccg attcgtttac ggaatgaata ttcattcctt 2643301 ttgttcacaa agaatgtctg ccctgtctga tatcacctct ttgttctttc ttctgttata 2643361 agtttatatg aaaaaaactt tttttaatat aaagtatatg caaaaaataa aaaattaaga 2643421 aaatataccc aaatcctaat acgaggatct tggatatatt tcccgagaaa ttttttattt 2643481 aacagccaca atacatagac aggaagcacg cctgataaca gaaagatccc tgaaatgctg 2643541 gtctttcagc agttgaatat acgttttctc tttttcaccg gtatttgtgt caatactgat 2643601 ataaaaccgg ccgtcaattt gaagcaccct gtaaatttct cttaatgcaa gcctaatatc 2643661 ggtgcagctt tgaaccgtat gtaaagaaaa gactttatta aaggtacggt catcaaaggg 2643721 aatgtcctct ggatagccat gaaaaacctc cccgttcccc atgttctttc gattcgcacg 2643781 tgatatctgt cttacctttc gttttgaagg atcaatgctt tttaggctac ccttttttag 2643841 tttcttggtt atgcttttaa agacagtgcc gtttccaatt ccaatttcta aaattctgtc 2643901 attttcttgt atatctatag agtcaatcat catatgctca attgttttgg ttagcttata 2643961 tttccgagaa aataatttcc aaaaatccga tcgtttatag agtctatttt ctagcatttt 2644021 aaacacctgc ttttggtttc ctatgtttat ttattatctt aaaaaaataa acatcatctt 2644081 catttctaaa agtgaaggaa ggtaccaact agacggcaat gtattgaaaa atgtttcaat 2644141 agaactaaac tttttcattt ttttccgaaa aaaaagcaga aaacataatg ttttctgccc 2644201 tctttctaat gccaatgata agggaataca tacagccttt gctgctgcat tgccatcagc 2644261 ctctgctgtc ggaatggatt tccataacca tgtttgaagg aatgcggcat ggacgcataa 2644321 ccatggccaa tcgacggcag tcttttttga taatcgttca tcatgccatc acctgcctca 2644381 caataacgtt gatttactat atgcaggcgc gcattttctt gacagctatt tcgctaaact 2644441 tggtccttct ccattgtata atgcatcaat agttccattc taagcatatg ccattccccc 2644501 ttcagttttt ttcgttgctt ttagcgccag tttgttaaat aaagatgctt taactgagac 2644561 tctttcattt catcataaat ttgttcaatc tgctgttctc gttcgaattc ttccaggctt 2644621 ttaaaccgtt ttttaatcgt taacgttaaa aagaataggt taatcgtcat atcgctcacc 2644681 ccctttcaaa gtccgcatca agcgaaataa cccgcggcac aacccttctg ccgcgggcaa 2644741 ataaaaaccg cagacaaaag aagacaccaa tgcctctact gcctgcgggg agttgcgtat 2644801 gtccgactat tccgaattta atgcgtgcga taagcatcgg ttaaggaagg acacgaactc 2644861 ttccacaggc tgaataaacc atgaactttt acatgtgtat cacgtacagg ttgacgtcgt 2644921 tgtctcattg tcattttggt tcagcctcct ttgctttttt cttactttgt aagtatatcc 2644981 accaaattcc attttgtaaa catctttttc taaaaatgga cggaaattgt gcaaatcatc 2645041 gaatggattt gcccgttggt catgacacct gcttcatttc ttttctggag cggtctttct 2645101 tatgatatgc aataaaataa atgagaccga caaatacagc tccgccgatg acattaccga 2645161 taaaagccgg aatgatgttt ccgatgaact gcccccacgt gaatgagcct gcaaaaatgg 2645221 cagcaggaat cacaaacatg ttggcgacaa cgtgctgaaa tccgatagcc acaaaagcca 2645281 tgattgggaa ccagatgcca aggatttttc ctgctgcgtc ttgggcgccg aaagaaagcc 2645341 acactgcaag acatacaagc cagttacagc cgatggcgga aatgagaacc ttgccaaagc 2645401 tcatatcaag ctttccttgg gcaacggcaa tcgttttttc taaataagga cctgtttcag 2645461 tcaatccaac caaatgcccg aaaaagtaag caacaaacaa tgcgccgatt aagttcataa 2645521 ttgtgacgat tccccagtta atcgctaact cttttactga tatttttctc gaaaataacg 2645581 ccatcgcaac tgacatcata ttgcctgtga tcagttcagc gccagcgaga acgacaagga 2645641 tcaggccgac tggaaatact gctgcaccaa tcaaactgga caggctcccc cattctttcg 2645701 gaagatcgcc aattaccctg atatcaagca aatacccaag cgcgataaat gcaccgccta 2645761 aaaaccccag cacaagcagt gacggcagcg ggagctttat ttttttcatc cctgcttcaa 2645821 ttgctgcttc cgctatttca tccggttttc gaaaagccat aataaaacgc ctccattact 2645881 tcttcttttc tcacagttat gcaagaaagg caataaaaaa ggcagcactc aaataacctg 2645941 tgtcaaacca ggcgtttgaa tgctgcctaa cttgtatgca tacccataca acaatatcaa 2646001 gcagtatata agatattgaa agagaatata tacagttcgt gcatacattc cattgcttta 2646061 gccttctata actgtagcaa catcatatca aatgtgacaa atttgtgtca atgacaaata 2646121 tactagcttt gcagagcttc tttttgctca tctatttttc ggtcaaaaac aaatacagat 2646181 acagcgatgt tttcctcaat tttaatatca gaaaacaaat ggactagctt agctcccata 2646241 agttcctcca ttccttccgg tgtttgtttg gaataaaggt cttgaattag gcttgtccgg 2646301 gccgcatgta ccatctctct tccttcaggc gtgcgggcaa taaactgctc gcttgcactc 2646361 agatttccgt atagtgttga aactgccatg ttttctacaa atacagtatg aattctctca 2646421 ggcccttttc cgaacaattc tttgcgaagt tttcgaataa tatcattgaa ttcatgaatt 2646481 tttttagaca tgctgattac cccttccgat attgccttat aaaggctttt cccggttccc 2646541 ctcaggacat ttcacttggt taaaattttc ctgccatatt gtattataat aaatatcaca 2646601 ttataataaa agcagtgttg atggatttgt aataggatct tgttatgagt ctatcgtttt 2646661 ataaaaatca aggattggtc tgttagtaag acttgctagt gaactattcc gccatgtgtg 2646721 tttacacctt cttagaatta agggcaggtg tatctataca tggctttttt tgacttcttg 2646781 aaagaaagat ggaggggaat atgaatatga tggacgttaa gtcgatcagt gtccgtgtag 2646841 acggaacaga aattcaagca cgagcagggg ccacaatttt agatatttta aatgaaaacg 2646901 gaattgagta cccgcagatt tgccacgtac cagaggttga cccgattcaa acttgtgata 2646961 cttgcatagt agaggcaaac ggcaagctgg ttcgttcatg cgcgacggtt gcagaaaacg 2647021 ggatgtctat tgatctttca ggaaatcgag tgaaagaagc gcaaaccgaa gcgatggacc 2647081 gccttcttga aaatcatttg ctgtattgta cagtttgcga taacaacaat ggaaactgta 2647141 cgctgcataa tacagcggaa atgatgggga tcgagcatca aaaataccca tacacgccaa 2647201 aagaagatcc ttcttgcgcg gttgatatgt ctcatccttt ttaccgctat gatccaaacc 2647261 aatgtattgc ctgcggccag tgtgttgagg tctgtcaaaa ccttcaggta aatgaaacac 2647321 tctcaatcga ctgggaacgc gaacgccctc gcgtcatttg ggatgaggga gttccgatca 2647381 atgaatcttc ctgtgtcagc tgcggtcagt gtgtaacagt atgtccatgt aatgcactga 2647441 tggaaaaatc aatgctcggg caggctggtt ttatgacagg cattaaagag gacgtcatgg 2647501 aaccgatgat tgatctcgtg aaaaatgttg aaccggggta tggcagcatt tttgccattt 2647561 ctgaagtcga agcggcaatg cgtgaaacga gaacgaaaaa aacgaaaact gtatgtacgt 2647621 tctgcggtgt cggatgttca tttgaagtat ggacaaaagg acgggatatt ttaaagatcc 2647681 agcctgtttc tgatgctccg gttaacgcaa tttccacatg tgtcaaaggg aaattcggct 2647741 gggattttgt caattcaaaa gagcggatca caaagccttt aatccgtaaa aacggagcct 2647801 ttgtggaatc ttcttgggaa gaagccctcg atcttgtcgc aagcagatta ggatcaatta 2647861 aagagcagta cggtaaaggc tctgtagggt ttatttcttc ttctaaaatt acgaatgaag 2647921 aaaactacgt cattcaaaaa ctagcgcgtc aggtatttga aacaaacaac gtcgataact 2647981 gctcacgcta ctgccagtct cctgctacag acggattgtt ccgcactgtc ggcatgggcg 2648041 gtgacgccgg cacgattaaa gatattgcca aagcaggcct ggtcatcatt gtcggtgcca 2648101 atccggcgga aggacaccca gtgctcgcaa cacgcgtcaa acgggcacac aagctccacg 2648161 gtcaaaaact gattgttgct gacctgcgta aaaatgagat ggctgagcga tctgatctgt 2648221 tcatcagccc taaacaaggc acagaccaag tttggctgat ggctgttacg aaatatatga 2648281 tcgaccaagg ctggcacgat caggcgttta ttgatgagaa cgtcaattac tttgaagatt 2648341 ataaagaaac ccttaaaacg tatacgcttg attatgcaga acgcatcaca ggcctttcaa 2648401 aagaaaacat cattcaaatt gctgaaatga ttcgtgatgc tgacggcact tgtgtccttt 2648461 ggggaatggg tgtcacacaa aatacaggcg gttctgatac atcagcagcc atttcaaacc 2648521 tgcttctcgc tacgggcaac tatcgccgtc caggtgccgg cgcttatcct ctgcgcggac 2648581 acaataacgt gcaaggcgca tgtgatatgg gaacattgcc tggctggctg ccgggatatc 2648641 agcatattac agatgacaaa gcacgcgcta aatttgaaga ggcatatggt gtcgagattg 2648701 atggaaagcc tggtttagat aatattcaaa tgcttcatgc cattgaagaa ggaaaaatga 2648761 aagctatgta tcttgtcggt gaggatatgg cactggtcga ttcaaacgcg aaccatgtgc 2648821 atgatatttt atcaagcctt gatttcttcg tggtacagga catcttcctg tcaagaacag 2648881 ctcaatatgc tgatgtcgtc ttgccggcca ctccttcact tgaaaaagac ggaacattta 2648941 ccaacacaga acgccgtgtc cagcgattgt atcaggcgct tccgacgctt ggtgacgcaa 2649001 aaccggactg gtggattatt caagaggtgg caaaccgttt aggagcgaat tggaattaca 2649061 gccatccaag tgacattttc tctgaaatgg cgagtctttc tcctctgttt gccaaagcaa 2649121 gctatgaggt gcttgaaggc tggaacagct tcctatgggg cagcttcaca ggtgaaagca 2649181 caccgcttct gtatgaagac ggatttaatt tccctgacaa aaaagcccgc tttgcccttt 2649241 ctgattggac cgagccagcg gcatttccgg aggaatatga ccttcatatc aataacggcc 2649301 ggatgctgga gcatttccac gaaggaaaca tgacaaataa atcgaaaggc atccaagcga 2649361 aagtgccgaa tgtattcgtt gagatctcac ctgagcttgc acaagagcga ggtgtttgtg 2649421 acggttcgct tgtacggctc gtttctccgt tcggagcagt caaattgaac gcgctgatca 2649481 cagaccgggt acggaaaaat gaactctatt tgccaatgaa ctcgacagac aaggagtcag 2649541 cgattaactt cttgacgggc cctgcagctg ataaacggac gaacacgcct gcttataaac 2649601 agacaaaggt ccgcatggaa gtgcttggcg gctgtgaaac agcgccgctt ccaaaaacaa 2649661 atccgcgcaa caaaaaacgg catccgcaaa acggagtcga agcagaaaga aaatggaacc 2649721 gccctggcta tgtacatctg actgattaaa cgataggagg aaaacgaatg gccactccga 2649781 ttacgacgat caaaaaagaa acaaaaacag ctgagcaaat taagcttgaa aaaatagaag 2649841 aactgaaaga gctgctggcg gaaaatgagg acgccgtctc taaaacgatg acgttaatga 2649901 atgaactcaa tgatcttgga atttttgatg cggcaacaag catgctcaga gcgaaggaag 2649961 acattgccaa gattgcgctt ggccaagttt cccgcgagcc tgtcaccaac ctcatcaaca 2650021 cgatgatggc cgccggaggc gcattgacaa aagccgatcc tgagtttaca gcaaagcttt 2650081 tagaaagcgt aatggctggg actgaacagg cacaaagctt tttaaaagaa gacaagaaag 2650141 tcgggattct cgacctgtta aaagcaatga acgatcctga catcaacaga gccgtcgggt 2650201 tcggccttca gtttttaaaa ggcatgggaa aagaacttcg agaacaataa cagaaaaaca 2650261 gccatctctg atgatggctg tttttttatt cgtcggcttc ttccagacgc ttcttgtaaa 2650321 taagtgaacg gtcagcgcaa aagaaggcac cggctaaaaa tacgcaatcc gctaaaaaca 2650381 tcgtcgattt ctggcctaat gttaagcctt gatcagggag aactgcgcct atatataaaa 2650441 aagtgctgac tgcaagcaat gtaaaagcaa aatgcttgta gtcttctttt aaagatttca 2650501 ttctattttt gttcaaaaga atcacctgcc agattcatag tatacgacta ttataatata 2650561 atccggcggc ttacagagaa agtaattcta tccatttgtt atatattttc aagcgcttgg 2650621 ccgatatctt ccaacaagtc ttccgcatct tcaattccta cagaaattct gatcaagccg 2650681 tccgtaatgc cgagctcaag ccggcgttct ctcggaatag aggcatgtgt cattcttgca 2650741 ggaacagaaa ttaagctttc aaccgccccc aggctttcag caatggtaaa cagtttcaga 2650801 tttcctaaaa acgcatcaac ccgttcttca ctgccaatat caaaggagat catgccgccg 2650861 aagcccgctc cttgcgtttt tgcaagctca tgtccgggat gatttgaaga accagggtaa 2650921 tataacgttt ggacagcagg gtgattctca agaaagcttg cgattttccg cgcattttga 2650981 tcgatcgctt ccattctgag tcccaacgtt ttgattcctc tcattaacag ccaggaatct 2651041 tgagggccga gcacgccgcc tgtggagttt tgcacaaaat gcagctcttc tccaagctct 2651101 ttcgaagctg tcacaactaa acctccgacg acatcactgt gtccgccaag atattttgtc 2651161 gcactgtgca gtacgatatc agcgcctaaa gtaagcggct gttgaaaata aggagtatta 2651221 aaggtattgt ctacgataag cagaacaccc gctttttttg cgatatcagc catgagcgtc 2651281 aggtcggtga ttttgagcaa cgggtttgtc ggtgtttcaa tataaattgc ttttgtatta 2651341 gggcgaatcg ctttttcaac ttcttccctg ctgctcgtat caacaaatgt tgattcaatg 2651401 ccaagacggt taagcacctt tgtcatcacg cgatatgttc cgccgtacac atcatcagtc 2651461 aacacgacat gatctccgct gttaaacagc atcataaccg ctgtaatggc agccattcct 2651521 gagctgaacg catagcctgc ttccccgctt tccagttctg tcacaagtgc ttcgagagcg 2651581 gttcgagtcg gattggccgt tcttgaatac tcgtagcctg tatgctgccc tgctttcggc 2651641 tgcttgtacg tgcttacttg ataaatcggc acggaaactg cgcctgtttt ctcatcacct 2651701 gtgattccgc catgtatcat caatgttttt ttcttcatat cagatgcctc cttcgtatat 2651761 ttgtttgctg atatatcgat cgctgctgtc aggaaatact gtgacaatgt tagttccagc 2651821 ggatgctttt ttcgcttcct ccaatgccgc ataaagcgct gcacctgaag agcttccgat 2651881 cagcaggcct tctttttctg ccgcttcttt cacaagtcta aacgcattct catctgttac 2651941 ggtgtagatc tcgtcaaaat ggctcttatc catataatcg gggataaact ccatgccgat 2652001 gccctctgtt ttatgagcgt ggggctctcc tccgtttaaa atcgagccca ccggttcaac 2652061 aatcaccgtt ttgactgctg gatttttttc ttttaagaag gaagctgtcc ctgcgaatgt 2652121 gcctcctgat cctgcccctg cgacaaatgt atgaatattc ccgtcaagcg cttcccacat 2652181 ttcaggtcca agcgtcttat agtaagtcga tggatttact cggtttttaa attgcaaaac 2652241 gcaataagaa ttttcaattt cagtctccag ctgaatggct ttttgaatgg ctccctgcat 2652301 tccgtcttga cgcggtgtat gaatgattga tgcgccaagc gcttgcataa tttgctgttt 2652361 ctctctgctg aaatgttcag ggacacagaa aatcgctttc agcccatatt ttctggcact 2652421 taacgcaagg ccgatccctg tattgcctgc cgtagcttct ataatcactc cgccgggttt 2652481 cactttgcct gaatcgagcg cgtcacgaat cagcatatct cccagtctgt ctttgatgct 2652541 tccccctgga ttcatcattt caagcttggc atacaccgcg actccttctg gaacatcaaa 2652601 gttcttcaag cggagaagcg gtgtattccc aatcagctcg gtaatgtccg taatcactgt 2652661 catatatgtc ctcctcctta atagaggttg tttttagaga aaaacggagg agaacgttct 2652721 ccccgtttta atgaattcgt ttgatcacct ttaacacaag ctctgttgaa tgaacagccg 2652781 cctgctctaa aaattggtca aatgaaacat gtgattcttt gcctgcgata tctgataacg 2652841 ctctgatgac gacaaacggc gttttaaatt gatggcatac ttgagccact gccgcagcct 2652901 ccatttcaac cgcgtacaga tcagaaaatc tcgcacgcac ctcttcaacc cgcttcggat 2652961 cgttcatgaa agaatcgcct gttgcaatcg ttccttttgc aacctgaatg ccgtcgagtt 2653021 cagataccgc ttcttcagtg atgctgatca gcttttcatc cgccgcataa gcagccggaa 2653081 gacccggcac ttggccgtat tcatagtcaa aagccgttac gtctacatca tggtggcgaa 2653141 cgtcagtgga aatgacgaca tcccctacat tcaatgtatg atgaaatccg ccggctgagc 2653201 ctgtgttaat gacataatca ggcttgtaac ggtcaagcag aagcgtcgtg ctgatagcag 2653261 catttacttt tccaattcct gattttaaaa gaatcacttc agttccttca tattcgcctg 2653321 ttgtaaattc acagtgtgcg atcgtttctg tttttgcatt ttcaagtttg tttcttaaga 2653381 tggtaacttc ctcttccatt gctccgatga ctgctagtct catctattca cattcccttc 2653441 actttaccgt ttgatcgcct ccattatcca cacgaagtcg ttttgctgag tgaatcggac 2653501 tgcaaaacct tcagctgtaa acatttcttt caacgcatcc aatgtaggat aatgctctgt 2653561 ctctaaatca tttgcaagct gataaaagcc ttgagaacgg gctttatcga tagcctgttg 2653621 atacgcttgc gcattttcaa agacggtatc ggcaaacact attttatcat gcaagtgaag 2653681 gtatttgcca tattgcttta tggcagcccg cttttcttcg tcagtcaaat gatgaaaagc 2653741 atatgaactg acaatcgtat cagcctgaaa tggcggctca gggaatgtca ggaagtctcc 2653801 atcaacgatt tccgtcctgc ctgagagctt gtcagaagcc agtttacgca ttgctggaga 2653861 aggttcgatt ccaaatacag ttttgcctgc atcgagcagc ttagctgtca aattcccggt 2653921 ccccgggcca aattctaaca catgcgttcc agattttctg acgatggcat caaggatatg 2653981 atcgtagcct ctgaacgctt ctttatactg aatatctaaa ccttgtactg tttgatcata 2654041 agttgctgcc caatcttcaa agagagggat aaattcacgg cccatatttg tcacactcca 2654101 tatttaataa ttcctataag tatactatgg attaatgatg gaacagttcc tataatacca 2654161 catattctga aaagcaggta ctaaaacact ttgtgtattt tatgccatct catattgcgc 2654221 attgaccgca aaaaagctta tacttcatat gacttgtgaa agctggaggg tcaagacatg 2654281 aattttcaat tagatctgat taaagacaaa gtggaatttt ttgaagcggc ttcattgcag 2654341 gagcttgaaa agaaaatcaa tacacaaatt gaaaacaata aagccatcat gctccgggtg 2654401 aaatctgttt cacaccaaac tcttgtggca gaaggaagaa tattgtacag cgcggtggtt 2654461 catttctcag ctgaagccta aaacaaaagc agccggtttt aacccggctg cttttgttta 2654521 ttttagcttt tctacttttg tcggcttcca gcctttttca tcgacccatg taatcgtgac 2654581 ttgatattta ttcccagtcg ccttgtccaa aatcttgcct ttggcatcct gagggctgcc 2654641 gttatttcca agccagagca ccgtcatgtt atctgttgag acaccagttg cgtacgaaat 2654701 ggctttcagc atctcagccc agtcttgtga gcttgaatca taagtagcgg catgctcgcc 2654761 agtctgctca gttccgactg ctttccagtc aggattttca tacgtttttt ccacatcgct 2654821 cgatgagccg ccttctgtta cttttgcatc tttaagcccg tcaccggctg aatctgagct 2654881 tgaatctgaa tcagagtcat cttttttaga agaagaatca tcttttttgg aatcagagtc 2654941 agaagacttc tcagaatcct tttcgctgtc agatgtatct ttcttgctgt cttttatatc 2655001 ctcatccgat ttcttttccg tctttcctga agccggagat tcctgttttt gcgccgtttc 2655061 agaatccttg ctgacatctt tgctagaagg actgttaatg aagagattcg ctgctactac 2655121 gacaattagt atggatacga ttgcgattaa aatgttaagc actaaattgg cttttctgcg 2655181 tttatcacga ttttcataac gagattgatt attgctcaat aattctgcac tcctttatcc 2655241 ctcttggctc agcatatatt ttaacatgtg ctgagaagtt gttctatttc tgattgattt 2655301 caatttcgtg tactttttta acaatatcat aaaacaccga atttgtcaga gccttatctc 2655361 ccggtgtatc catgtgtaaa acaactagag cgtatttcgg cttatccgcg ggaaaatatc 2655421 cggcaaacca tttttcgtag agcgtttcct tctcttttga aagcttgcct gtctgggctg 2655481 tgcccgactt ccctgctaca gtatacggaa gatcttgaaa ccttctgccc gttccggaag 2655541 gagattctac tacccgccgc agtatttttt gaagctgctg tgacgtatat ttgtctatcg 2655601 tttccccttt gagcttctga tctttaaacg taacgagcgt tgtgccgttc ttatactcaa 2655661 tttgttcggc aattttcacc tgccgttttt ctccgccgcg ggcgattgtc gccatcatat 2655721 tggctacctc cagcggcgtt acctttacat ttttctgccc gattgctgtt tgcgcaatgg 2655781 cttttttgac tgatttgtct ttttcatccc cccaaatcac gccgcttttt tcgttataca 2655841 gctggcggaa atcggtttcg tggtacagtt ttccctccca gcctgcccga tcagtgagag 2655901 ccagcttctc ggacatatct tcaataaccg agctgtcttt tttcattaat tgttctgcaa 2655961 gactcgtaaa tgtgtaatta cagctttggg caaaactttc atcaaaagac aaggtgcctt 2656021 tgtcgtcccc cggttccccg tacaggttta aattgcaatt aaaggtttga ctaggcttca 2656081 ccatattatt ttcgattgca gctgcggcaa tgactgtttt aaaaactgat ccgggataga 2656141 ttggcgtcag catataattt tgaagtgtgt tttgccggga cacgtctgca tctggtttgc 2656201 ttacaattcc cagaacactg ctattttcga tgtccagcag cacagctcct ccctttttca 2656261 gcccctgttc atccaatacc tcctccatcg ctttttgaat gctttgatcg atcgttgttt 2656321 tgatctggag cggataaaat gtattggctt cagctgtata tttgacgtcc atgccaaaca 2656381 aagggtttcc ttttccgtcc acatgatata aaagctttgt gtcttgttcc ggaagcaaaa 2656441 actcgtcaaa tgtccgttct aaaccggttg ttccgatttc tgttgtaatc ggaaggctct 2656501 ccttgtcagg atatttcttg cgaagcagcg ccggatcttg gttcgtgctc cctatcgtat 2656561 gtgaagcaag gctgggcttg tcttcattct ccatatatac gccgtaaatg ccgggatatt 2656621 tcaaagaatt gatttttgtg atagattgtt ttgaaagtgt tttgattttc ttttgctgca 2656681 aaatgaccgg tttttttgcc tgacctagtg tctggcgcaa atcatcttca gacatgccga 2656741 ggatgtccgc aacttttttg atcggccaat cctgcgtcag cagaaaaggg aacaaaacaa 2656801 ccgcaggctc gctttgtcct gtcagcgccc gcccgtttcg atctaaaaaa gagcctcttc 2656861 catctgaaat gagcacttcc tccgtccgct gtttcacact ttcttgaatc aaattaattt 2656921 tctttttaga aaatgattct gtgaaaaaca gctggatttc tgcaagtctc agcagaagca 2656981 gaaaaaatac aatcaaaaaa gcgatgactg ccagcttcat tcgtttcgat atcttcataa 2657041 aaaaacacct cacccacatt gtggacgagg tgtttcgctg ctaaacagat attatgaaat 2657101 tttcacaatt ttcacgagca tttctccgcc cggtgtttgt actgtgactt cttcatctac 2657161 ttttttgccc aagaggcttt ttgcgatcgg tgaatcgttt gagattttcc cttcaaacgg 2657221 gtcagcttcc gcgcttccga cgatcgtata tgattcttca tcaccgtcag gcagttcgac 2657281 gaaagtgacg gttttaccca aaccgacaac gttagagccg ccgtcatctt caatgatttt 2657341 cgcattgcga atcatatttt caagagtcgt cacgcggccc tctacaaatg cctgctcttc 2657401 tttcgctgaa tcgtattcag agttctcgga aaggtctccg aagcttctcg caattttgat 2657461 tcgctctact acttcttttc gtttaaccgt tttcaaatat tctaattctt gttcaagttt 2657521 ttgttttcct tctgcagtca taggaaaaac tttctcttgt gccatgtccc ttcactcctt 2657581 ctggttgtcc ctcaacatct tcgattatgt atgagagcat aaactaaaaa atacaagaat 2657641 gagaacacag ggcagtcctc gttcttctct cccatatagg tactgtttat cttaaactga 2657701 atcgtgtcgt tctgcaaata tttcgcgttt ataaacaggg aaagaaggga attcgcacat 2657761 tcccttcctg cctatacata atatggtcag agttatttat gtctatgcta tggtattaca 2657821 aaatcgcgtt ttgttcaaga atggtttgaa tttttgtgac catcagatca attgcgacgt 2657881 gattctgacc gccttccggg ataataatat cagcgtatcg tttcgtcggc tcgacgaatt 2657941 ggttatgcat cggacggacc actgacacat attgttcaat gacagaatca atagagcgtc 2658001 cgcgctcatt aatatctctc ataatccgtc tgatgatacg caagtcagcg tccgtatcaa 2658061 cataaagctt gatatccatc agatcacgaa gccttttgtc ttcaagaaca agaatgcctt 2658121 caaggataat aacatccttt ggctctacgt gaaccgtttc ttctgaacgt gtgtgaagct 2658181 tatagtcata aatcggcttt tcaatcgggc ggtaattcaa tagatcttga atatgctcga 2658241 ttaaatagtc attatcaaac gcaagcggat gatcatagtt tgtgttcagc ctttcttcaa 2658301 acggaagatg gctttggtct ttataataaa ggtcctgctg gatcattaaa attgagtgtc 2658361 ctttaaactg ttcataaatg gaccgtgtga cactcgtttt tcctgaaccg gaacctcctg 2658421 cgattccaat gactactgga ttcttaccca tgggctgtta cttccccttt ctcatcatgt 2658481 tgctcggata aatctttttg tctagtttga atttgacaat ttgcagggga tggcgggcag 2658541 catctagctc atttccgtct tcgtcccaaa tggtttcaat cgtatgtgta aagttttcga 2658601 tttctggacc gaaaaattcc acttcgtcgc cttttttgaa gaaattgcgc tgctgaagcg 2658661 tgaccatttg tgtatcttca tcataattca gcactaagcc gacaaaatca tatgtcgttt 2658721 tcttggcgtg ttcgccgaac atttgctctt catagcctgg cgttccttca aagaaagctg 2658781 tcgcagtgtc cctgttggcg cacttatcaa gctcttcaag ccattctttt tgaatcacaa 2658841 agttttctgg atcagcgcaa taagcatcga ttactttgcg gtatacgctg acaacagttg 2658901 ctacatagtg aatggatttc atgcggcctt caatctttaa gctgtcgatc cccatttcaa 2658961 tcatttttgg aatggattca atcagcttca aatctttcgg gctcatcgca aatggtgcat 2659021 cttcttcacc atacaaagca acggcgttgg caccgtctgt ttggtagaga tcataatccc 2659081 agcggcatga ctggcagcag cctccgcggt tggaatcccg cgctgtcatg tgattgctca 2659141 gcacgcagcg gccggaatat gcaatacaca ttgcgccatg aatgaaggat tcgatttcga 2659201 tatctacctt ttctttcatt tctctgattt caagagcgct agtttcacgt gccagcacga 2659261 cgcggtcgag accttcttcc ttccagaact ggacagcctt ccagtttgaa agagactgct 2659321 gtgtgctcaa gtgaacctca acattcggcg ccactctgcg gcatgtttca ataataagcg 2659381 gatctgccac aataataccg gcaacgttgg cgtctccaag cgcttttaaa tagtcttcaa 2659441 gcccgtccat gttttcatta tgagcgaaaa tattcgttgt tacgtagatc ttcgcgccat 2659501 atttctttgc gaattcaacg ccttctgcaa tttcttcgat cgtaaagtta tcggcattcg 2659561 agcgaagccc gtattcctgt cccccgataa agaccgcgtc cgctccgtaa tgaacagcga 2659621 ttttcagctt ttcaagatta cccgcaggtg cgagaagctc cggctttttc gtaatcacac 2659681 gctttccatt aacgattgtg gatattttat catttacggc agtcatagct taacctcctt 2659741 ttgattaata aaccgtttcc ttgaagaaga atccggtatc aatttttctg tttactggct 2659801 ggatgctttc aatgcgttcg atccagtctt cttttttcgc ttcgtattcg tcacggtttt 2659861 ccacgcacaa atcaattgct tctctgtaca ttttggtgac ttctattagg tattcaggca 2659921 ttttcaaaac accatcgatt ttgaaagaat caattccggc atctatcaat tcctcgagct 2659981 catcaatgat gcacacatcg ttcgggctca tgatgtgagt gccgttttca tcttcgaaaa 2660041 tcggatattt attatcgcgt tctttatcgt gtaaaaacat gcctgattct tttttctttc 2660101 tttcaatgtc catgactttg ccctgatatt caaaatagtt tccaatcaaa gaacgcttcg 2660161 attggaacat gcacgtcatt ccatgcacct ggatttcaat ttcgacttca gcattttctt 2660221 taatctcaac aatgctgtcc atgtttaatt ctctggcaag cacagaacgc gccgcaccct 2660281 tgcgtcccca gtagttgcat gtataatagt tggtgcctgt cgtttctgtg ctccaatgaa 2660341 gcttcagatc aggcgcagat tcacgggcag ccatcagcac ggcaggatcg ccgaataccg 2660401 ctgcatcgac accggcttct gctaagaaag ccagatattc gccaagctca cccactttat 2660461 cattatggaa aattgcattt acagcaacgt atacttttgc cccttctttg tgagcaatct 2660521 ctacggcttt tgttacatct tcacgagaaa attctccggc taatctcaag ccgtatctct 2660581 gttccccaac taaaaacgca gttgccccag cctgtatgag cggcaaaatg tccgctgtac 2660641 tcgtcggcgt cactaagagc tctggttttt tcatgacgtt cacctcttct ttttactaat 2660701 cgcaagtccg tccccgacag gaataatcgc agtttgataa tccggatgat tcatcagcca 2660761 atgattatat tcatcaattt tggctacaag cctgcgcctt ctcttcggtt ctattttgct 2660821 gtaatcctct gccaccagac ctttaaacag cacgttgtct gttataatca ccccgtccgg 2660881 tgaaagcatc ggttcatata aatgaaaaaa gttttgatac tgaccttttg cagcgtcaat 2660941 aaaaatgaca tcgtaaggcg cggttacatg aacggcgtcg gctaattcaa gcgcatctcc 2661001 gtaaaaaaca tgaatccggt catcaagctg aaattccttg atattgttta ccgcttcttc 2661061 atgccgtttc tcattgcgtt caattgtata tatttcagca gacggcagtt ccagagccat 2661121 tcgaatggct gaataaccaa tggccgttcc gatttctagt atttttttcg gctgtttcac 2661181 agacaaaatt tgaagcagca cctccatgcc cgctttttcc ataatcggga catgatgttc 2661241 ttctgcatat gcttcaagtc tcttcacgtt atccggccga ggctttaata atgcttctat 2661301 atagtcattt atttgttcat accggtcagt cactacaaac agcctcccgt tctaaaaagg 2661361 agtgccccag tcttatgcgc aggacactct ctgaatacat catgatacat cggtaaacaa 2661421 cccgatatat tttatcataa aaccttgcgg aaagcgaaca aaaggagagc tttttgctct 2661481 ccttttattt ctcatttttt gaggaaatgt atttttcttt tgctttatta tgctctttta 2661541 gcgtttttgt aaatacgacc tcaccatttg atttggccaa gaaatacaga tagtccgttt 2661601 tatccggatg cagcgctgct tcccatgatg acatgccggc attggcaatc ggccctggcg 2661661 tcagccctgt gtttttatac gtattgtatg gtgaatcgat ttccagatcc ttataaagaa 2661721 cccgatcttt atgcttgcct gccgcgtaca ggacggtcgg atctgtttgg agcggcattt 2661781 tctttttcag gcggttataa aagacgctcg caattttatg gcggtcggct ttttcagtcg 2661841 cttcttcttc tatcaaagaa gccattgtca gcagcttatg cacagaaact ttgtttttct 2661901 tcatttctga tttatatgtt tccacataag aatttgtctg cttaatcatt gccttgataa 2661961 tgtcttcaag tgatgtgtcc ggatcgttaa aagggtatgt agccgggaat aggtaccctt 2662021 caagcgggtg cttaatgttt ttattgaaaa catcatttgt cacagtgtcc gggaattctt 2662081 tcttcagctg attgataaat gtttcatcgt ccagcttcgc tatgacttgt tttttagagt 2662141 attttgtttc atcagcaata gcagccgcga tttgggtcag ctgtgctccc tcagtcactg 2662201 tgatttgaaa agcgtaacct gtagccccgc ttgtcagctt ctgaataatg gcatctaaat 2662261 ccataccttt attcagatgg tagaatccgg cctgaaaccc ggaagcacct ttatatttca 2662321 catagtactg aaacgccttc tcgcttttta tgacatcatt tttctttaat atcgatgcga 2662381 tggctgaaac agacgaaccg ctcggaatgt taatattaac tgtcgtttta ctgtcttttt 2662441 caacaggttc aagcaatgat ttcccatata aaaatgcccc gccaatgatg agaaacagca 2662501 caacaatgga agacagtatg attctttttt tattaaaaaa cgattttttt tgctgattga 2662561 tatacattag gtctcctccc atcagctctt atactacatg attcattgta tttcggcaat 2662621 ttattacaaa aagaggcctg cataaagcag aaaaaagccg gagcagtata gctccggctt 2662681 tggtttggcg cgatgtttta ctcttcgtct tcgtccgcta agaatgtgtt tagtgtttct 2662741 tcgatcatat cccattcttc gtcagtttca atcgggaata gctcaccgtt ttcaccgtct 2662801 tcgtttggcg tgaagctgga agcaagaatt tctacttctt cgtcatcttt tgattcgatt 2662861 ggatagtaca agacataaga tttgccaaac tcttcatttt caaatgtaaa cagcacttca 2662921 caaagctgtt catttccttg atcgtcaaca attgtaatat ttttttcgcc gtgttccatt 2662981 ttcttcacct ctggctttaa tttaagctgt caagatatcc ttgtaaaatc ataacagccg 2663041 ccattttatc aatgactttt tttcgttttt gcctgctgac gtcagctgca atcagcattt 2663101 tttcagccgc cattgtggta agacgctcgt cccacagcac aacaggaaca ttgtacgttg 2663161 tttcaagcac tttcgcaaat gtttggctgg cttcgcctct cgggccgact gttccgttca 2663221 tgttcttagg aaagccgagc acgattttat ctatagtata gtcctttatc agttcagata 2663281 aacgggataa accataatcg ccttctgctt catttatctt tatggtctca atgccttgag 2663341 cagtccagcc catttcatcg ctcagagcta caccgagtgt tttggttcct aaatcgagtc 2663401 ctaatattct cattctttat ttacgcctct ttatgctgtt ctaaataaga ctttaccaat 2663461 tcctcgatta attcgtctct ttcaagtttg cgaattaaat tgcgagcgtc acgatgccta 2663521 ggaatataag cgggatcacc tgacagcaag tatccgacaa tctggttgat tggattgtag 2663581 cccttttcct gaagcgcgtc atacactgta atcagcacct catttacgtt agtctcagca 2663641 gaatcatcgg agaaattaaa tttcatcgtt ttatcaaacg agctcaccgt tttgcacctc 2663701 tttcccaaat tcgcaggcaa agttcagcct ggggtcctaa tcttaccatc attctacact 2663761 acatgggcga attataaaac ggatttcacc caatcttcta cagaagccaa agcttcttct 2663821 aatttttccg gctgtttacc gcctgcctgc gccatgtccg gacggcctcc gccgcctccg 2663881 ccgcaaactt ccgcagcttg tttaaccagc ttgccggcgt gaagtccttt ctcaatgagg 2663941 tcctttgtga ctccggcaga gatattaact ttatcgtttt gtaccgcacc aagcacgatc 2664001 accgcagagc caagctttgc tttgagttca tcgaccatag tgcggagatg attcatgtct 2664061 tttgcattta cttttgccgc aagcacgttt acgccgtcaa cttcttttac tttcgacagg 2664121 attgctcctg cttccacgtt gcctagtttt gcaagaagag attcattttc tctttgtgca 2664181 tccttcagtt cagcctgcag agccgcgacc cgtttcggca cttctttgat atttgttttc 2664241 agctcgtcag cggtctgctt caatacagaa atctggctgt tcatttcgac gtaagcgcct 2664301 tgtcccgtta cagcttcaat ccgtcttgtg cctgctccga ttccggattc agaaacgatt 2664361 ttaaacaagc cgatttctgc tgtatttctg acgtggcagc cgccgcacag ctctaagctg 2664421 taatctccaa cttgaacgac acggacaata tcgccatatt tttcgccgaa cagtgccatc 2664481 gcacccattt cttttgcttc agcgatcggt ttcaaatcaa tgctgaccgg gatgctcgcc 2664541 cagatctttt cgtttacgat tctttcaatt tgttcgagct cttcttttgt cacttggcca 2664601 aagtgcgaga agtcaaaacg aaggcggttt tccgttacaa gagagcccgc ctgattgaca 2664661 tgagttccaa gaacatcttt tagagcctga tgcaataaat gcgttgccgt gtggttttta 2664721 atgacgccgc ttctcatatg gtcttcaact tcagccgtaa catgcaggcc tttttgaaca 2664781 gtaccgctct ccacaacacc ttcatgcaca tgctggccgt tcggcgcttt ttgaacatct 2664841 ttaattctta caactgcctg ctcgcttcgg agatagcctt tgtcgccgat ttggccgccg 2664901 ctttctgcat agaacggtgt ttcatcaaga atgatttgaa cgctttctcc ttcatgagcc 2664961 tcttcgatta attggccgtc ctgaagaagc acaatgatat tggcatcagc tttggtttga 2665021 gagtagccga caaatgtgct ttcaactgtc acgtcgcgca gtgcgccgcc ctgcacctgc 2665081 atgctgccga catcctggcg ggcgtttctt gcccgttcac gctgctggtt catttcctcc 2665141 tcaaagccct catggtcaac cgtcatgttc tcgtcttctg cgtattcttc agtcaattca 2665201 accgggaatc catacgtatc atacagttta aacacatcag cacctgagat aacgctgctg 2665261 cccttgtctt tttctttttt gatcatttct gacaggatcg caagcccttc attaagggtc 2665321 tcatggaagc gttcttcctc ggttttaatg acttttgcga tgaaatccgc tttctctttc 2665381 acttcaggat agaaatcagc catgatttct gcgacaaccg gcactaaatc aaacatgaac 2665441 ggacgatgga tgttgatcgt tttggcataa cgcacggcac ggcgtaataa gcgtcttaat 2665501 acatagccgc ggccttcatt tgacggcagc gcaccgtcac tgacagcaaa ggcaaccgtt 2665561 ctgatatggt cagcaatcac tttaaacgca gtgtctttca cattgtcttt gccatatgtt 2665621 tcaccagaaa tcgattctgt tgctttaatg atcggaacaa acaaatcggt gtcaaagttt 2665681 gtcggaacat tctggatgac agacaccatt ctttcaagac ccatgcctgt atcaatattt 2665741 ttctttggaa gcggtgtgta cgtgccgtca gggttatggt tgaactctga gaacacaagg 2665801 ttccatactt ccaggtaacg gtcgttttcc ccgcctgggt aaagctccgg atcttctgga 2665861 tcattaccgt atgcttcacc gcggtcgtaa aagatttccg tattcggtcc gctcggccct 2665921 tcaccgatat cccagaagtt cccttccaga cggataattc tttcttcagg aataccgatt 2665981 tttttcgccc aaaactcata tgcctcttca tcttcaggat gaaccgtaac agagagaagc 2666041 tctttgtcga agccaatcca cttgtcgctc gttaaaaact cccaagccca tgtaatggct 2666101 tcttctttga aataatcgcc gatggaaaag tttccgagca tttcaaagaa agtgtgatgg 2666161 cgcgcagttt tacctacatt ttctatatcg tttgttctga tcgctttttg agcgtttacg 2666221 attcttggat tttccggcac gacacggccg tcaaaatatt ttttcagcgt cgcaacaccg 2666281 ctgttgatcc aaagcagtga aggatcctca tgaggcacta atgacgcgct tggctctacc 2666341 gcatgtcctt tttctttaaa gaaatccaaa aacatttgac gcacttccgc agaagttaag 2666401 tgtttcattg tatttcctcc tctataaaaa tcgaaattct cttcagtgac agcaaaaaag 2666461 ccctccccct atgcaaacca acgtttacac agggacgaga gctgtctcgc ggtaccaccc 2666521 tgattacggg cattcatgcg cccgtcacct ttaaccctgt aacgcaggat aagcggcagt 2666581 gattaactgc actcaggatt agcttcctcc gatcttctga taaagctcct ttcagcttat 2666641 ggagcttctc tctttaacag ggcttcggcg tactcagatc cgtcactcga gattcgtatg 2666701 tattctacga gaaattatag acaagcggca cgccgatgtc aatgctccgt cctcatccgc 2666761 aaaaaatgga tcatcattac ttttaaaaca gccgtcgcag gaacagccag aatcatcccg 2666821 acgatacccg caagctcccc tccggcaagg agtgcaagca tgataacgac cggatgcatt 2666881 ttaaggcttc tgccgacaat gaacggactg aggatatttc cttccataaa ctgcagaata 2666941 aacaccgtaa tcaccacaac aagaaccgcc ttgactgaga tcgtcatcgc aattaacaac 2667001 gcaggaacag ctccgatgaa agggccaaaa tacgggatga cattcgttac cccagagata 2667061 aggccaagta tcagcggata cggaagccca aatacccaga acgaaatgcc tgcaatcacg 2667121 ccaagaatca agcagaccaa aagctggccg cggatataat cgccaagcga atcatccaca 2667181 tcccgcaaaa aggcgctgcc ccgctttctc cacgacttcg gagtcaagta ccatactgtc 2667241 tttttcatta actcaatgtc cttcaccata taaaacacga gaaaagggat tgttgcagca 2667301 attaagaagt aatcaagcac attgcggatc ccgctgatcg caccctcgat cgttcccgca 2667361 aaaaacgcct ccgtctggcg gatcatttta tctatacggt gatgcatacc atcaggccag 2667421 tcatccgtat ggttatgcac atgaagaaga agcccgttat acgtttcggc aaacatgggt 2667481 atattttctg acaaatccgt cagctgcacg attaaaacag gcaccccttt atacaacgcc 2667541 cagccaatcc cgccaaaaaa aagaacataa atgaccaaga tgctcaaagt cctaggcaat 2667601 cctttgccat gcagccattc tgtgaccgga agcaataaat aagatataaa aatagaaatg 2667661 atcaagggaa taaagatcgt ttttatgacg agccaaaagg gtgaccataa catatcaagc 2667721 ataaaaaaga catagactgt taacagaacc agcaaacaaa tagccaccca caacaaaagc 2667781 tgcaccggtt tttggagcat ctgctttcac ctcacctata tcttttgagg tttacaagga 2667841 attattcttt atgtttcttt agtcagtcag aagtcatgga cattttttca cttttaattt 2667901 tcagaaaagt ttgatcattt actttttggt caaattttct gataggagga ttgcgatgat 2667961 cacatttcaa aatgtaaaca agcattacgg agattttcac gtgttaaaac aaattaatct 2668021 tcaaatcgaa aaaggtgaag tcgttgttat catcggccca tccggttccg gtaaaagcac 2668081 attgctcaga tgcatcaaca gacttgagtc gatcaatgag ggagtgctta cagtaaacgg 2668141 caccgccatt aacgacagaa aaactgatat caatcaagtg cggcaaaata tcgggatggt 2668201 gtttcagcac tttcatttat atccgcataa aacagtgctg cagaacatca tgctggctcc 2668261 ggtaaaagtg cttagacaat cacctgaaca agcaaaggaa acggcgcggt actatcttga 2668321 aaaagtcggc atcccagaca aggctgacgc ctatccttcc cagctttccg gcgggcagca 2668381 gcagcgtgtt gccatcgcaa gaggactggc gatgaagccg gaggtcatgc tgtttgacga 2668441 gccgacatca gcacttgatc ctgaaatgat cggtgaggtg ctagatgtca tgaaaacact 2668501 cgccaaagaa ggcatgacaa tggttgtcgt gacacacgaa atggggtttg ccaaagaagt 2668561 tgccgaccgg attgtcttca ttgacgaagg aaaaatttta gaagaagcag tgccggctga 2668621 attttacgcg aacccgaagg aagaacgggc ccgcttattc ttaagccgta ttttaaatca 2668681 ttaaaacaga aatgggggag cttgtatgaa aaagattttt tctttagcat tgatttcttt 2668741 attcgctgtc atcttgcttg ccgcttgcgg cagcaaggga tcaaacggag aagcctcaaa 2668801 ggagagcaaa aaagatacgc tagccgccat taaagacaat gacaaaattg tcttcggcgt 2668861 aaaaacggac actcgactgt tcggtcttaa aaatccaagc tcaggtgaga ttgagggttt 2668921 tgatattgat attgctaaac aaatcgctaa agacatttta ggtgatgaga aaaaagctca 2668981 atttaaagag gtcacctcaa aaacaaggat tcctatgctg caaaacgggg atatcgacgc 2669041 cattgtcgcc acaatgacga tcactgaaga acgaaaaaag gaagttgact tttctgatgt 2669101 ctatttcgag gccgggcaat cgcttctcgt gaaaaaaggc agcaaaatca agagtgtcga 2669161 gaatcttggc aaaggctcaa aagttcttgc agtaaaaggc tccacctcct ctcaaaacat 2669221 tcgtgaaaag gcgcctgaag catctgtttt agaatttgaa aactacgcag aagcctttac 2669281 agcccttaaa tcggggcaag gcgatgccct caccacagat aatgcaattt tatatggaat 2669341 ggctgatgaa aataaaaatt atcaattaac aggaaagcct tttacagatg agccttacgg 2669401 gatcgccgtg aaaaaagggc aatctgctct cgcgaaagaa atcaacgctt cacttaaaaa 2669461 gatgaagtcg gatggcagat acgatgaaat ttataaaaaa tggatcaaag aagacccagc 2669521 tgaataacaa ccatcccggg atgagcaggc gatgctcatc ccaatttgat aaggagtgaa 2669581 taggcagatg aatgtgtcaa ttcttttcga taacttcagc atgtatatgg acggttttta 2669641 ccataccttg ctcgcaagtg ttatcgcgct ggccggcagt tttgtcctcg gcgttgctgt 2669701 agcggttatg agaataacag tctttaagcc gctgcaatgg ctcgggaccg catatgtaga 2669761 attcatccgc aacatccctc ttcttttaat tacctttgtt ttctatttcg gacttccaaa 2669821 cgcaggcctg aggcttgacg gttttcaagc gggaacggtt gctctcacca tttatacctc 2669881 tgcgtttatc gctgaagcca tcagagcagg catccagtct gtttcaaaag ggcagatgga 2669941 agcggcacgc tcgtcaggct ttacctacag ccaagccatg ctccatatca ttttgccgca 2670001 ggcaatcaaa atcgtcattc cgcctttagg caatcaattt ttaaacttag tcaaaaactc 2670061 ttcgattctt ggggttgtgg ccggattgga tcttatgtac caagccgatt tagtttcgtc 2670121 gagcacactc gttgtatttg atgtttatat ttttgtggcg cttttttact tagtgctgac 2670181 gattccgctt agcatcggtg ttaactatct ggaaaaacgg ctggaaaaaa gctattgata 2670241 aggagtgagt tacattggat ttcatcggtg cttattcaca ggagcattta gcgtttttat 2670301 gggatggctt tctcgtcacc ttgtacgttg ctttcatctc catcattctg agctttttct 2670361 tcggtttaat cgcaggcacc ctgcgttatg cgaaagttcc cgttctttct caattgattg 2670421 cagttctcgt tgaaacgatc agaaacctcc ccttgctgtt aattattttc tttacgtttt 2670481 ttgcccttcc ggaaattggg attaagcttg aaattacagc tgctgcaatt acagcactaa 2670541 cgatttttga atccgctatg ctatctgaaa ttatccgaag cggactgaaa tcaattgaca 2670601 aaggacaaat tgaagcggcg cgctcctccg ggctgagcta tacacagacc ctgttcttta 2670661 tcgttatgcc gcaagcgctt cgccgcatgg ttccgcccat cgtaagccag tttatttctt 2670721 tattaaaaga tacatcgctc gctgttgtga tcgccctgcc tgaactgatt cacaacgcgc 2670781 aaattattaa cggccaaagc gctgacggca gttatttttt cccgatcttt ttacttgcgg 2670841 cccttatgta tttcgcagtc aactacagcc tttcactcgc agcaagacgc ctcgaggtcc 2670901 ggcaaacata gaaaaggata ctctttggag agtatccttt ttgcattaaa acattttcgt 2670961 aattcttctt ctcatccgct tcatgcttcg attattcagc atgtcagatt gagtcgccat 2671021 tcggtacacg agagctccgg ctcccattgc caaaagagaa gtcatcgtcc gattcatcct 2671081 gcgcatctcc tttcatgatt aaaaattgat gctgcgttca tcctcagaaa acaaatcatc 2671141 caagctgctt aacgttccgt cttcttccac ctgatgagtt gcaatcttcc ctttcgccac 2671201 tgtcagttca ataaaacagc cccagcaata atattggttc acgccgattt tgccgatatc 2671261 cttacttttg caattcgggc atataagcat acctcacacc tctatccgtt cagaacgatc 2671321 tcgtctttcc gcacctcgac aagcgaatcc gctctttgga tctggcgctt gcttcccgcc 2671381 aggtcagaaa agaaaccgtc cgagagttca tatgctacga ttatgcccct gtccaaacaa 2671441 aagtatacat cttccagcat ccccaatata tccccctctt gcgatttcac aagcttcatc 2671501 ttcatctgct cgtatgtgaa gcatgatttc ggaagaggca aaagctgttc tgaactgacc 2671561 gaagccaata tgcggtcatc aaaaatggaa gagatatcac acgcccgtaa tagcgcatga 2671621 tgatgatgca aaaagcgttt ttgtgcaaga ataaacccaa gacaatctcc tttcagagaa 2671681 aaacaaatat cggaaattgt cccgagataa ctagaagttc gttctgagta tactgggaat 2671741 ccttctactt catggcatgt tctcaaagtg tgatcaacca ccttttgttg aacaggctta 2671801 ggttttgctt tgcgccttag actcatacga tgaaatcaat tccactgcaa atgaaaaaaa 2671861 actcccgctt gcacgggagc attttattgc tgttcttctt tcataaaatc gaatggtgta 2671921 atgccttcca tgccaatgtt ggcgtcgtgt acgctgaacg ggagctcttt ttgcaaagct 2671981 tcaagctcgg catccatttc ctcaacctgt acggacagcc tgtttttcaa ggaggtctgt 2672041 ctgacagttg catcattatt tttcacgccc cactccagcg cctcctcttc cccgcataaa 2672101 atgagaaatt tcttcgctct tgtaatcgcg gtataaagaa ggtttcttct gagcattcta 2672161 taatagcctt tcacaacagg caaaaccaca atcggaaatt cacttccctg cgatttatga 2672221 atagaacagc aatacgcatg ggtaaattga ttaaaatctt ttttcgtaaa tgtcatttca 2672281 ttgccgtcaa aagaaacgac ggccatgtct tctttttctg tattttcctt tgcataaaat 2672341 atcgacgtga tttcgccaat atctccgttg aacacattgt tttccggctg attgacaagc 2672401 tgcaaaattt tatctccggt tctgtagaca acatccccga acttcaattc tctccgtttt 2672461 tctttaggag gatttaaaat gtcctgcagc atcacattca attcattaat gccggctttt 2672521 cctctgtaca tcggagcgag gacctgaatg tcctttgctg tatagccttt tttcaatgca 2672581 ttggcgacaa ccttctcaac tacttctttg atttgcgacc cgccgcagcg aataaaggaa 2672641 cggtcctttg tcggggcagt caaattgttc ggcagcaatc catttttcat ctggtgggca 2672701 agctcgacga ttgatgaccc ttctgcctgg cgatagatgt ctgtcagtct cacagtcgga 2672761 atcacctggg atgccagcag gtctctgagc acttgtcccg gaccgacgga aggcagctgg 2672821 tcttcgtctc cgacaatgat gatttgtata tgatcaggga tcgccttgaa caaatgattc 2672881 gccagccata tatcaagcat actggcttca tcgataatta acagcttccc ttcgatcggc 2672941 tgatcctctg tatgagtaaa gccttcagcg ccgttccagc caagcagcct gtgtatcgta 2673001 actgcaggga gtcccgttga ttcactcatc cgttttgctg ctctccctgt cggagcggcc 2673061 aaaacaatcg gaaaagcttc atccttttta taagctgacg ggtctagtga cacaccgtga 2673121 agctctccgt agagctcgac aatccctctg attaccgtcg tttttcctgt tcccgggccg 2673181 cctgttaaaa gaagcatcgg cgaggaaagg gctttttgaa tcgcttcctt ctggctgggg 2673241 gcatactgaa cgtccatccg ttcttccagt tctcccaacg cgagcaaaaa ctctgattcg 2673301 ggaaactggt tctcatattc ggtttggcta gcgatatgtt tcacacgctt tgcaacgttt 2673361 tgttctgcgt aaaacagcga aggaaaataa cagcggccat cttctatgac aatgtcttta 2673421 ttttctccaa gggcaataat tgcgttagcg gcatccattt ctgtaatgcg ctgcccttcc 2673481 cttgctgact ggtttaacag tgattgagtg tcgatgatca gctgttccgt ttctatgtac 2673541 gtgtgcccct ctgacagaca agtcgtttca agcgtgtaca aaatagcagc ttttacccgc 2673601 tcaggatgat tacccgaaag acccattctg ctgcccagct catccgcttt tccaaacccg 2673661 atgccttcta catccttcac aagctgataa ggattttcct gaatcttttc aagcgtctcg 2673721 gattcatagg cttgatagat tttcatagac agctgcgggc caaagccaaa ctgattcaag 2673781 gaaatcatga tttgctccag tccctgatgc cgctgcaatg cgccagccag cgtgtctgct 2673841 ttcttttttg agagtctggg aacatcataa agcactgaag catcagccaa tattttatta 2673901 atggcgctgt cgcccagctt tttcacaatt tcttcagctg tttttttgcc gatcccctcg 2673961 aataaatcac tcgataaata ttgaatgatg ccttccttag tcgttggaat ctcctttttg 2674021 aaatgctccg cctgaaattg gagcccgaat tttggatggg ttacgatctt tccgtaaaac 2674081 gtgtaggtct cttcttcttg aagcgcaggg aagtagcccg tcacggatac ggctttatct 2674141 tcaatggctt cggaggtctc tgtgactttc actttcagaa ccgtatataa attggtgtca 2674201 ttatgataga tgactgtgtt gactgtccct tttaaatagg gctcttcctc cagtttaagc 2674261 tgatccggat gctgctgcac gagctgtccc tcctcctgtg cctgttatga tggatcaatc 2674321 agttttttag catgaagcgc aagcatatga tctggctgga tatcgattgc cttgtccagc 2674381 atttccagcg ctttttctcg gttttcttta taagcataag tgacaccggc attataaaat 2674441 gcatctgcat gccccgggtc ttgctctgtc acagctgcga attggctgag cgcttcgtcc 2674501 agcatgccct cgttggctaa gcacatcccg aattgaaaac gcgcttccgt atcgttttca 2674561 ttcagttcga ctgctctttg taaatatggc agtgcaagct taggctgttc gagcttgaca 2674621 agtaccgttc cgagcatgta aaacaggtcg ccgttttcca tccccgcacg tagcgctttt 2674681 tcaaacatgt ctttcgcttc tttgtacatt tcttttacaa catagacatt tcctgctcca 2674741 taataagcag tggctgcgct actgtctaat tcaagcgctt tatcataaaa cgcaagcgca 2674801 cgttccagct cgtttacgga tgaaagaagg ttggcaaaat tgatatacgg aatcgcgtct 2674861 tctttatttt cttcaatcgc ttttgtaaat gcctctgccg ctttctcgta atcgccttcc 2674921 tgcatcgcct ctataccgag ttgattataa tccaccgatc atcttccttt cattaaaaaa 2674981 ccccaactca gtgttgaggt ttttcatctt ttatacgtac cacaattttg ttccgtcttt 2675041 gtacacatca tcaattgtcc cgccgccaag gcattcttcg ccgtcataga agacaacggc 2675101 ttgtcccggc gttacagcgc ggacttgttc atcaaagatg acttccgctt caccttcgcc 2675161 agtcatgcgc actgttactt tatgatcctc ttggcggtaa cggaatttag ccgtgcagga 2675221 aatctcttcg cccttcatga tatccgaacg tacccagctg atatttgttg ctgtgatttt 2675281 gtcggaatat aaaagcgggt tatggaaccc ttgatctacg tagaggatgt tcttttcaag 2675341 atctttgcct accgcaaacc acggctcgcc gcttccgccg atgccaaggc cgtgacgctg 2675401 tccgatcgta tagtacatca acccgtcgtg gcggcctttt acttcgccgt ccatcgtcat 2675461 catatcgccc ggctgtgcag ggagatattg gctgagaaac gttttgaagt tgcgttcgcc 2675521 gataaagcag atgcctgtac tgtctttttt cgtcgctgtt gcaagttctg cttctttggc 2675581 aatttcacgc acacggcttt tttgaagttc gccgatcggg aacatgactt tgctcagcgt 2675641 atcttctgtc agctgattca ggaagtacgt ttgatccttg ttttcatcaa tgccgcgcag 2675701 cattctgact tttccgccgc ttctgtctac tcttgcatag tggccagtcg ctaaatagtc 2675761 ggcgccaagt gacaatgcat gctccaaaaa ggccttgaat ttaatttctt tgttgcacaa 2675821 tacatccggg tttggtgttc tgcctgcttt atattcatca aggaagtatt gaaatacctt 2675881 ctcataatat tgcttttcaa agtttacggc ataatacgga attccgattt ggttgcagac 2675941 gcggatcaca tcttcataat cctctgtcgc cgtgcaaaaa ccgttttcgt ccgtatcatc 2676001 ccagtttttc ataaagattc cgattacatc atagccctgt tcttttaaca gcagggccgc 2676061 cacagatgag tctactccgc cggacatgcc gacgacgact cttgtatcct ccggccgttt 2676121 ttccatttca ttcactccaa ttactacgcc gccttattat gtcagccgtt tgacaacgtc 2676181 ggccacatgt ttggcagcag ttttcacttg ctcagccgta ttgccgaggc cgaagctgat 2676241 tcgaatagag gacgtcagcc ggtcactctc ttcgccgaac atagcagtca gaacatgtga 2676301 cggcaggact gaaccggccg tgcacgctga accgctggag acagcgacac cagccatatc 2676361 aagattaacc agcagcgctt ccactgacac accggggaaa taaagattca gaacatgcgg 2676421 cagactatgc tctttgtccc cgttgacctc gaatgccaca cctgcatctc taagcgtgtc 2676481 ggcaaagatt gctttaaacg attgatactt ctcgtttttt tcgtcacgtt cttcacttga 2676541 cagcttgatc gcttctttca gcccgacaat gcctggaaca ttttccgttc cggcacggcg 2676601 ttttctttct tgctctcctc cgaataaaag gggtgaaagc ttcacatctt tactagcata 2676661 taaaaagcct gtcccttttg gcccgttgag cttgtgcccg gaaacagaca gaaggtcaat 2676721 atggctgttt ttcacatcaa ttggcagcaa cccgaatgcc tgaacagcat cggtatgaaa 2676781 ataagctttg tgttccttta acagctcacc gatttcttcg atcggctgca ctgttccgac 2676841 ttcattattt ccatacatca ctgtcacaag gattgtatca tcacgcagtg cttctttcac 2676901 ctgttttgca ctgactcttc cattttggtc aacgtccaga tacgttatgt caaatccgtc 2676961 tccctcaagt ttttcacatg tgtgaagcac ggcgtgatgc tcaatttttg ttgtgatgat 2677021 atgtctgcca agatcttttc ttgcaagtgc ggttcccatg atcgccaagt tatcagcttc 2677081 cgttcccccg cttgtaaaaa tgatctcctg ctctgccgct ccgatttctg ctgcgatctg 2677141 cgctcttgct tcatccaccc attttcgaga ttctctgcca aatgaatgaa tactggaggg 2677201 attaccgaaa ctgccggaga agtgcggtat catttgttcc agcacgcgct catccatcgg 2677261 agacgttgcg gcatgatcta aataaatccg ttccattatg tttacacctc tgatctaaat 2677321 atagaacata taagcttctt gctctccgtc tgtatagctg gcaagatcct ctaatgttgt 2677381 actgtctaaa acctctttta cagcatcccg gatgcgaatc cagagctcac gcttggcagg 2677441 ctcctcatct tccagcactt caacagggct gatcggcccc tcaagcacac ggataatatc 2677501 tcccgcagta atggcatccg gctcactgcc taatacatat ccgccatatg cgcctctgat 2677561 gcttttcact aaaccggcat ttctgagcgg cgataccagc tgctccaaat aatgctcgga 2677621 caaattattc gtctgtgcga tgctttttaa tgaagtcggg ccttcaccgt gcttttttgc 2677681 aagctcgatc ataatggtga gcccgtatct tcccttagtt gatattttca acatgaacac 2677741 ctctgttatt tcatgatttt ccacatttat aatggtaatt tctatatgtt tcgtccgttt 2677801 attatcttat agaccaactg ttattataac ataccttcag cgaattttca ttgaggcaga 2677861 aggaaagggg cctttaccct tttctaatgt acggttttcc gttaccctgt aattaagtaa 2677921 ggagagatga tagatgaagc cattggcata tcggatgcgt ccgacaaaaa tagaggatat 2677981 tatcggccag cagcatctgg tggctgaaga taaaattatt ggcagaatgg tccaggcaaa 2678041 acatttgtca tccatgattt tgtacgggcc gcccggaatt ggaaaaacat caatcgcaac 2678101 agcaatcgcc ggttcaacaa gtattgcttt tcgaaagctg aatgctgtca ttaacaataa 2678161 aaaagatatg gaaatcgtag ctcaggaagc caagatgtcc ggccaagtga ttttgattct 2678221 ggatgaagtc cacaggctgg ataaaggaaa acaggatttt ctattaccct atttagaaaa 2678281 cggaatgatc attttgatcg gagcaacgac ggctaacccg tatcatgcca ttaatccggc 2678341 gatcagaagc cggacccaga tttttgagct tgaaccgtta acacctgaac tgattaaaca 2678401 ggcactggaa cgtgcgctcc atgatgagca tcggggcctt ggcacctatt ctgtatccat 2678461 tgatgatcag gcgatggagc attttgccca cggatgcgga ggagatgtcc gctccgcttt 2678521 aaatgcgctt gagcttgccg tgttgtcaac gaaggagtca gcagacggtg aaattcacat 2678581 tacattagaa accgcggaag aatgcttgca gaaaaaaagc ttttctcacg ataaagatgg 2678641 tgacgcgcat tatgatgtac tgtccgcttt tcaaaaatca atccgcggct ctgatgccaa 2678701 cgctgctctt cactatttgg ctagattaat tgaagccggt gatctggaga gcatcgcaag 2678761 acgattgctt gttatcgcct atgaggatat cggtttagca agcccgcaag ccggccctag 2678821 agtgctgaac gctattcaga ccgctgagcg agtcgggttt cctgaagcgc gaatcccgct 2678881 ggccaacgca gttattgagc tttgcctctc accgaaatca aactctgcca ttctggcaat 2678941 cgatgaggcc ctggcagata tcagagccgg aaaaattggg gatgtcccga agcatttaaa 2679001 agacgcgcat tataaaggag ctcaggaatt aggaagagga atcgactata aatacccgca 2679061 caattacgac aacggttggg tcgaacaaca atacctccct gatcctctga aaaataagca 2679121 atactataag ccgaaacaga ctggaaagtt cgaatctgcc ttaaagcagg tgtacgataa 2679181 attaatgaaa agaaaataaa acaaaaaaac agccttgatc atcaaggctg tttttatgca 2679241 ttatttatcc ttcacacgtt tgatttcaat gtctttcaaa agatccatga caacatgtcc 2679301 gcccataatc aaacctgcaa ctgacggcac aaaagcatta gaggaaggcg gcatttttgc 2679361 tttacgtatt ttcgcttcgt cattccccac ttcttttctg acatcttccc gaataacaat 2679421 cgggctttca tcagagaaaa tcacttgaac gccttttttg ataccctcct tgcgtaattt 2679481 cgtacgaacg accttcgcaa ttggatcagt gtgcgttttt gagatatcag cgatttggaa 2679541 gcgtgtcgga tccgttttat ttgcagcacc catgctggag atgagcggaa tatcccgttt 2679601 tagacattct ttcattaaat gaattttata acaaatggtg tctgacgcat caatgacata 2679661 gtcaagacca tagtcaaaaa actgctcata cgtttcctcc gtatagaaca tttttaacgc 2679721 gatcacttca cactccgggt taatgtctgc gatccgcgcc ttcattaaat caactttcgg 2679781 ctgtccgaca gttgaaagca gcgcgtgaag ctgacgattt acatttgtaa tgtcgacatc 2679841 atctttgtcg acaagcagaa tgcggccgac gcctgaccgc gcgagagctt ccgccgcgaa 2679901 cgacccgact cccccgactc caagcacagc aactgtgctg tttttcagcg tttcaaggcc 2679961 ttcttttccg atagctaatt cattgcgtga aaactggtgt aacaagaacc tcactccaca 2680021 ttcgtattct ggtttcatct ataaaatggc tgatccatga gcagccgttt tttctgcgca 2680081 caaaaaataa agtcccaata gtgccgttgc agctttcctt tgttttgaac ccgctctcag 2680141 caggtgggtg ccctctttta aatcttgtaa gtcctcttta ccgaatgaaa agaggcatgt 2680201 acgccattta aaaatgcggg ctcccaaatc aaaaaaatgt tcggtcaaaa ctaggtgtac 2680261 aactaacaca tcaggacttt atttaacttg tcaaaatcat atcacagacg attttgattt 2680321 tcaagaatcg aactgcaaat tcagttctta acttttttct tgatagaaag atgaagctcg 2680381 tcaagctggg cgtcgcttac ttcgcctggc gcttctgtca tcaggcagct tgcacttgcc 2680441 gttttcggga atgcaatcgt atctctcagg ttcgtacgtc cagcgagaag cataacgaga 2680501 cggtctaagc cgagtgcgat tccgccgtgc ggaggagcgc cgtattcaaa tgcttccagc 2680561 aggaatccga actgttcagc cgcttcttct ggtgagaagc cgagaagcgc aaacattttt 2680621 tcctgaatat ccttttcgaa aatacggatt gaaccgccgc caagctcata gccgtttaag 2680681 acgaggtcat aagcttgcgc tttcatgtct tcaggcgctg tttcaatcag ctcaaggtct 2680741 tctcggacag gcattgtgaa cggatggtgc gctgcgtaaa aacggccttc ttccggatca 2680801 tgctctaata gcggccagtc gatgacccat aagaaattga acaatttttc gtcaatcagt 2680861 ccgcgttctt tcccaagctt taagcgcagg gcgccgagtg atgcggccac aacttcgaat 2680921 tgatccgctc cgaacagcag caaatcacct tcagcagcat caagtgcttc aatcagctta 2680981 gactgctttt cttcatcaaa gaatttagcg atcgggcctt tcactccgtc tgcctcaacc 2681041 ttcacccagg caagcccttt tgccccgtag tttgcagcaa aagcgccaag agcgtcgatg 2681101 tcttttctgg agtaatcgcc ggcaccgcct tttacattga tggctttgac cacgccgccg 2681161 tttgctacag ctgatgagaa cactttaaat tccgtatcct ttacaatgtc agacacatcc 2681221 gtcaaaagca tgtcaaaacg cgtatccggt ttatcagacc cgtacttgtt cattgcttcg 2681281 tcatacgtca ttcgaggaag aggaagctga agttcctcac cttttgtttc acgcataacc 2681341 tttgccatca tctcctcagc caatgacata atgtcttcct ggctcataaa ggacatttca 2681401 atatcaattt gcgtaaactc aggctgacgg tccgcacgca agtcttcatc gcggaaacag 2681461 cgggcaattt gataatatcg ttcaatgcct gataccatca gaagctgttt aaatagctgc 2681521 ggagactgcg gcagcgcgta gaactcacct tcgtgcacac ggctcggcac caagtagtca 2681581 cgtgcgcctt caggcgtgct tcctgttaaa atcggcgttt caatatcaag aaacccattt 2681641 tcatctaaaa agctgcgaac agctttcgtc acgttatggc gcagctgcat cgtctggaac 2681701 atagccggtc tgcgcaaatc taagtaacgg tgttttaaac gaacgtcctc tgacacttct 2681761 tcagcttgat cagaaatcgc aaatggaggt gtctttgcag catttaatac gttcactcca 2681821 tcagcatgta tttcgatcgc gcctgttttc aaattcggat taactgttcc ctcttcacgc 2681881 gccaccactt ttccttgaat atcaagcacg tattcatttc tgatgccttc cgcaatagca 2681941 agcgcttctt ttgacacatc agggttaaaa acgacttgaa caatgcccgt acggtcacgc 2682001 aagtcaataa aaatcaatcc gccgaggtct cgtctttttt ggacccagcc tttcagcgtt 2682061 acagattcgc caattgcttt ttcagttata tcaccgcaat aatatgttct tccaaacaat 2682121 gcgtttcact ccttatccct tttggtttgc cttcatcaca tgtataaatt catcaagtgc 2682181 cacttcaatc tgttcgcccg tctgtgcatc ctttacattg attttgtttt gggcaagctc 2682241 atcttcaccc aaaatcgcaa taaatctggc ctttaagcga tcagctgttt taaactggcc 2682301 tttcattttc ttattttcat aatcgatttc actggaaatg cctgcttctc tcagtttgta 2682361 caccaatgaa acagaataat cctttgcttt ttcgccgagt gtgacgatat agcagtcgat 2682421 tcccttatca acaggcagct ctcttttttc agcatcaatt gcggcaagca agcgttcgat 2682481 gctcatcgca aatccgatgc ccggtgcttc aggtccgccg atctgttcga caagcccgtc 2682541 gtagcgtccg ccgccggcaa gtgtcgtaat cgcgccaaag ccctccgcat tgctcataat 2682601 ttcaaatgcg gtgtggttgt aataatccag ccctctcaca aggttcggat cgatttcata 2682661 cgaaatgcca agatcattta agtattgttt cactttttca aaataagcgg ctgattcttc 2682721 atttaaatat gtcaaaatcg aaggtgccga tttcatcagc tcatgatcac ggtctttttt 2682781 gcagtccaaa attctaagcg ggttcgtgtg cagccgggac tggcagtctg aacaaaattc 2682841 ttcgatgcga ggctcgaagt gtttcacgag cgcttctctg tagcttttgc ggctatcttg 2682901 atcgccgaga ctgtttatga caagcttaac gttttctaaa cctgcttttt cataaatact 2682961 catcgcaagc gccattactt cagcgtcgat tgcagggtct ttcgaaccaa tcgcttcaat 2683021 tccaaactga taaaactggc ggtaacggcc cgtctgagga cgttcataac ggaacatcgg 2683081 cccgacataa taaagctttg tcggctgtac aggatttgcg aacagcttgt tttcattaaa 2683141 agcgcgaacc gcagcagctg ttccctccgg acgaagcgtc aggcttctgc ctttgcggtc 2683201 ctcgaaggta tacatttctt tttgtacgat atccgttgat tctccgacgc ctctggcaaa 2683261 cagttctgta tgctcaaaaa tcggtgtgcg gatttcttta tattgataag tgcggcaagt 2683321 gtctctcata atttgttcaa caaactgcca gcgatctgat tctccaggca gaatatcctg 2683381 tgttcctctc ggaatgttat atcccatagg tagacctcct tatgtattcc ttataaaata 2683441 tccaatgatc gttaatgatg aaaatgaaaa aaactcccgc ccctactata catgatagta 2683501 gggacgagag ttatacccgt ggtgccaccc tagttggaat acgttcatat tcccgctcga 2683561 tcctttaacg caggttcacg ttcactgcct aatggcgtta ttcacgcgtt cagcaggaaa 2683621 cctccggagt gttgtttcga gaaagacgca atgggatccg ctttcagcct ggggcgggtt 2683681 cctctctaat catgcaatct gacctactct tctccattat tggttcaaat ctttcatcat 2683741 ttgctatgta ctcaatttct attataataa tgggattggg gttctctgtc aagctttatt 2683801 ccggttgttt ttcctcagcg ctgcttcttt ggacataaga ccaaattcag atgctgtttc 2683861 cgtaagataa ccagtcgtat cgggatctgc gtgatcgctg taatgcagat tcgcttcacc 2683921 gtcgtgaaat gcacgtccca tttttggatg atatttcatg atttgcacac ctttttgatt 2683981 gtatttacgc ttagtataaa caaatcattt tatttttatt taaaaatcag aaaggacttt 2684041 acgatattaa acaagaatgc ttttttaatg atcatcagaa aggaggacac aatgaacaag 2684101 aaatactttg tccttattgt atgtattatt ttcacctcag cgctattccc gaccttttca 2684161 tccgttacag ctgctcaagg agaagcggtc atcgcaacag atgaaatgaa cgtcagaagc 2684221 ggcccagggc ttagctacgg cattacagcg gaagtaaaaa agggagaacg ctatccaatt 2684281 ttaaaggaag atggagactg ggtgcagata cagcttggtt ctggagaaaa gggctgggta 2684341 gtctcctggc ttattacaaa ggaagaccag gccagcacaa gctcctcagg aagcagtgac 2684401 actgtgacat caacagaccc cgatctgcgg atgagaagcg gcccgggcac ttcctacgaa 2684461 gtcatcggca aattcccgca aggcagccaa gcatctgtca ttgataaaga ttcgggctgg 2684521 atcaagatat cctatcacag tgccaccgga tgggtatcat ctgaatatgt cacatcagga 2684581 ggcagcagtt cagcgtctga tgagagtgac caaaccgagg attccggtgc gtcaacgacg 2684641 ggcacagtcg gtgtttcttc gctaaatgta agagcctccg cctcacatga cgcggcaatt 2684701 ataacaaaac ttgatcgcgg aacgaaactg acggttctca acgagaaaaa tggctgggct 2684761 cacattgagg tgaacgggct aaaaggctgg gttgcaagcc attacctttt gactagttct 2684821 gttccagctg atgattcagc aaatgccggc agttcatcct ccgctaaaaa agcctatatc 2684881 atgtacggag gaacgaatct aagaagtgat gcgtcaacat cagcttcgat cgttgagcgc 2684941 gctgccaaag gagattcata caccattacc ggttcaaagg gaagctggta tgaaataaag 2685001 cttgataacg ggcagactgc ttatgtagcc aattgggtgg tccaaacgtc taaaagcgca 2685061 gaagaagcag gtgaaccgcc agtctctgat tccccgtctg gaaacggctc tctaaacaat 2685121 aaaacgatta ttgttgaccc gggacatgga ggaaaagaca gcggaacgat cgggtattcg 2685181 gggaaattcg agaaaaacct gacgatcaaa acggcaaaac tgctcgccag caaacttaga 2685241 tcggctggag cggatgtata tgtgacacgc caggatgata cctttgtcag cctgcagtca 2685301 cgggtctcta cctctcacta ccgtaacgct gacgccttta tcagcattca ttatgacagc 2685361 tatgcggata cctctacaag aggcagtaca gcatattact acagtcctgc caaagatcag 2685421 gaactcgcat cagatgtcca ctcagaagtg gtgaagcgtt cttccattcc agaccgcggc 2685481 gtattattcg gagattatta tgtgctccgg gaaaacagac agcccgctat gctgtacgag 2685541 ctgggatatg taagccatcc gcaggaagaa gccattgtac atagcaattc ataccaagaa 2685601 aaagtaacag atgggatcga aagcggatta gagaaatact tccaataaaa aaagctgcct 2685661 tttggcagct ttttttattt tgaatccata atgagcgtga ccggtccgga gtttgtaagc 2685721 tgaacatcca tcattgctcc aaacgttccg gtctccactt tgattccttt ttcacgaagc 2685781 aggtcattcc atttttcata aagacctaaa gctttatcag gtttggccgc gttcatgtag 2685841 ttcggccggc gccctttttt cgtatctcca taaagcgtaa actgtgagac ggataaaatc 2685901 tctcctccta tatctacaag agacagattc attttccctt cactgtcatc gaaaatacgg 2685961 agattgacaa ctttatcggc taaataagct gcatcatctt ctgtatcatc gtgagtgatg 2686021 ccgaccagca ccataaggcc ttgtccaatt tggccgacga cctcttcgtc cactgtaacg 2686081 cttgcttctg ttactcgctg aacaactaat ctcttttcta acccctttag ttcatgacgc 2686141 ggcgcacaga atagatatct ctaatctgtt taatacgctc gacgacttta tgcaagtgat 2686201 tgatattctg gataaaaatc gccatatgga tggttgccac tttattgcga tccgatttgc 2686261 cagagacaga tgaaatattg gttttcgttt cattcactgc ctggagtacc tcgttcagca 2686321 atccgcggcg gtcataccca agaatctcta tctcaacatt gtattccttg cgcttttgaa 2686381 cttgtgactc atgttcccac tctaccggga tcagccgctc ttgggcttca ttcgttttga 2686441 cattcggaca gtcttcgcga tggaccgaaa cccctctgcc ttttgtgata aagccgacaa 2686501 tatcatcacc tggcacagga ttgcagcatt ttgataaacg gacaaggagg ttgtcaatgc 2686561 ccttgacacg aacgccagct tcccgttttc ttccttgcgg gtatggctta ggttccccag 2686621 tgacttcctg aacgatcttt tcctgttctt cctggtcgcg ctgctttctc tctttttctg 2686681 ttaggcggtt cgccacctgc agagctgtga tgccgttgta accgaccgcc gcgtacatat 2686741 cctcttcatt tgagaaatta aatttgtcag caaccttttg aatattctcc ggcgttaaaa 2686801 catccttcaa ttcaaaatcc aagtttttaa tttctttttc gaccagctca cggccttttt 2686861 cgacattttc ttcacgccgc tgtttcttaa agaattgacg gattttatgc ttcgcttggg 2686921 atgtttgggc aagcttcacc caatcctggc tcggaccgta ggaatgctta gaggtgagaa 2686981 tttcaacgat atcacctgtc cgaagcttat ggtcaagcgt aaccattttt ccgtttactt 2687041 tggcaccgat tgttttattg ccgatttcag agtgaatccg gtaagaaaag tcaatcggaa 2687101 cagaaccgga cggaagctcg attacatctc cttttggcgt aaagacatac accatgtcag 2687161 agaacaaatc aattttgagc gattccataa attcttctgc atctgtcgat tcattttgaa 2687221 attctaaaat ttcacggaac caagaaagct ttttctcaaa ggttgcacct tcattggctg 2687281 ctttcccttc tttataagcc cagtgagccg caaccccgta ttccgctatt tcatgcattt 2687341 caaaggtgcg gatctgcact tcaagcggat cgcctttagg cccaataacc gttgtatgaa 2687401 gcgattgata catattcggc ttcggcattg cgatataatc tttgaatctg cctggcatcg 2687461 gtttccagca tgtgtgaatg atgccaagca ccgcgtagca gtcctttatg ctattcacaa 2687521 gaatacggac agccaacaaa tcgtaaattt cattgaattg cttattttgc agcaccattt 2687581 ttcgataaat gctgtaaata tgtttcgggc gtcccgagaa gtcagccttg atatttactt 2687641 cttcgacacg tttcttcact tcattgacaa cctcatcgac ataaagctct cgttctgcac 2687701 gtttcttctt catgaggttg acaattctgt aatattgctg agggttcaaa taacggagcg 2687761 ccgtatcttc caattcccac ttaatttttg aaatcccgag acgatgcgcc aaaggagcaa 2687821 aaatttccag cgtttcattg gagattctcc gctgtttttc ctgaggcaga tgtttcagtg 2687881 tccgcatatt gtgaagacga tccgccagct tgatcaatat gaccctgata tcttgagcca 2687941 tagcgacaaa cattttgcga tgattttccg cctgctgttc ctcttgagat ttatatttaa 2688001 ttttgccgag tttcgttacg ccgtctacaa gcattgccac ttcttcggaa aatgcttctt 2688061 tcaggtcatc gagcgtcaca tctgtatctt ccacgacatc gtgcaaaaat ccgcccgcga 2688121 ttgtggaagg gtccatttca agatcaacga gtatccccgc aacctgaatc ggatgaataa 2688181 tatatggctc gcccgatttg cggtattgct cgcgatgagc atcttcagcg tacagatatg 2688241 ctttttcgac aaatgcgata tgctcatcag atagatagct gcgtgcttta tctataactt 2688301 gctcggcagt caatacttgt tcgttcgcca tggaatcacc ttttttaaaa tgtaaactgt 2688361 attgtagttt attatcaaga aaaaaacgaa agatgtaaag agcagaagtt caaatagcca 2688421 aatattatat aaaataaatg caaaacaata ggaaaaaagc accctgacat ggagtgcttt 2688481 ttcgttatgc ggttatcctt agtatttcat caatgttaag atgtcgtaat cttcgagctt 2688541 atttctgccg tcaaggtaag aaagctcgat taagaaagcg ataccagcaa caacgccgcc 2688601 aagttcttca acaagtttga ttgtcgcttc aattgtgccg cctgtcgcaa gcaggtcatc 2688661 tgtaataagc acacgctgac caggcttaat cgcatctttg tggatcgtta atacgtcttt 2688721 tccgtattcc aagccataat ccactttgat tacttcacga ggcaacttgc cttctttgcg 2688781 gaccggcgca aaacctacgc caagcgcgta agcaacggga cagccgataa taaagccgcg 2688841 cgcttcaggg ccaacgacca aatcaatttg cttttctttc gcatattcaa caatttgatc 2688901 tgtggcatag cggtatacat cgcctttatc catcagtgtc gtaatatctt taaattgcac 2688961 gccctctttc gggtaatccg gtacaattgt tacgtattgt tttaaatcca tctgttttat 2689021 gtcctcctcg tactttcata agcctctgaa tcttgtttca tcagcttatt cagccattcc 2689081 ttcagctctt cagcagaaga ataattcagc ttttgatcca gttccatcag ctgctgtttc 2689141 gcctgatatg tttgtgagtc tgttaagtcg cgtttctttg ctccgctcac aacagacagc 2689201 acaccattct ctattttaac aaaaccgaga tcaaaaaaca cctttgtcat gaaattgatt 2689261 gtttcaacgg accagccttt atgttttgca agctctgaac cgtgtttttt cacgtcaaaa 2689321 gcgcctcttt tcagcaagaa cgcataatac catttaaagt ggtctcttgc gggaaaagtt 2689381 gataaaaagt ggtcctcatg attgagaaaa ataaaatata tccgctcggg cgcctttcct 2689441 tccagcaaac gtgcgagcat gtccagcgaa ggcggcggat ccagtaatac aatatatgca 2689501 ccatcgaggt caaacgcctt tgcttgatct ttagaactga tgacgtgcac ttctcggcga 2689561 aggtcttcag tttgaagtaa tgttgttgag tcttctttga aagagacaat ggcccgttta 2689621 gcagatggaa gggcggaaac tgtgtcttcc cacgtccgtt ttccccttaa atcaaacagc 2689681 tgccattcag aaacagcggc atcctttatc ataagctgcg gcttttttcg attgttccat 2689741 tcgttgattg acatctcacc gacaatggaa attcttgaac ccggtacgat gccttcttga 2689801 agctcgcctt tattaaaacc gacgcaatca agctgggacg actcgtttct gatcgtcatt 2689861 ttgacatgag ttttatttgc ccctatcttg cggacatctt ccagtactgc attttctacg 2689921 agaacgtgcg gtttcgggtt cagcatgcca aaaggagaca gcatgttcat ttctgcgatg 2689981 ctttcaactg taatgtcttc gacgccgcag acaaggtcga cttcctgtac gggaataaaa 2690041 tcctcttccg taagcgtatt gtccgctatt tcattcagcc tgcttcgcaa atccggcaca 2690101 tcttcggctt tcagcgtcat ccccgcagcc attggatggc cgccgaaatg aggaagaata 2690161 tctctgcatt cagaaaggct ctcaaataaa ttaaatcctc tgatgcttcg ggccgaacct 2690221 ttagcgattc ccttttcttc atcaatacca agaacaatgg ccggtcggta gaaacggtcc 2690281 acaagctttg aagccacaat cccgacgact cccgggttcc atccggcttt ggccacgaca 2690341 attgcagttt gatcgagccc ttgctgttca accatttcaa tcgcttcatc cgtcattttg 2690401 ctgaccattt tttggcgctc tttgttcagc tggtcaattt ctgcggcaag ctcttccgct 2690461 tcaaacgaat cctctgacat aagcaaatga acagcgggat ccgcctgttc gattcttccg 2690521 acggcattca gccttggtgc gagctgaaat ccgactgttt cttcgttcgc ttctccgatg 2690581 tctccgcctg acagcttaat cagctctttt aagccgagcc gatttgtccg tcgaagcctt 2690641 tcaagtccta gtgttgctat taatctgttt tcgtcatgca gcgggactag atcggcaatg 2690701 gtgccgatag ccgccaggtc aagcagttca tcaggaagtt cacccaataa agcgtgggca 2690761 agcttaaacg cgactccaac cccggcaagc tctttaaacg ggtaagtgca gccaggctgc 2690821 ttcgggtgga cgatcgcacg gacatccgga agctccggtc ccggttcatg atgatcggta 2690881 atgatgacat ccagtccgag ttcctttgcc accttcgctt catgcacagc ggcaattcct 2690941 gtatcaaccg taatgatcaa agagaagccc cgttctttaa tcgaacgaaa cgcctgttca 2691001 ttaggtccat atccttcttt aaaacggtca ggtatataaa aatcaacttg agccgacagt 2691061 ttttgcagcg tgtgaagcat cactgacgta cttgtaaccc catcggcgtc ataatcgcca 2691121 tatatcataa tcttttcttg ttgtgaaatc gcctgtttta ttcgatctgc cgcttctttc 2691181 atgcctttca tttcaaaagg atcataaaaa tcggcatcct ttgtatgtaa aaacagccta 2691241 gcgctttctg ccgtatcaaa gcctcttttt acaagcaggg acgcaacaag aggtgttata 2691301 tgcaattgtt ctgtgagtga tttgacctta tcctgatctg gtcgctggat ttcccatcgc 2691361 atttttgacg ctaacataaa ttcacccctc aaccacccta ttatactaga gcaggctgag 2691421 gggtttcaaa taatattcga aaactagtct tttttctcaa tcatggctga tgcatcctgt 2691481 gtgtcagtct gatcagcaag atgagtatcc tcttgtttat gtattgctgt tctattttct 2691541 ttccgcaagg tttttatttc ccgcttcaat ttcattacct gaaaaatgcc gacagaaaat 2691601 acgatcagtg ctcccattaa aactgagccc aaaataacaa gaatgagcgg ccattctgat 2691661 cttccaaaca ggtaatcaac ttctacggat cgaacattaa tgactgcgaa aatagcgaca 2691721 attaaggtga aaataagtgc gaaaataatg gtccattgtt tattcattct cttttccccc 2691781 aaacttctta ttgaggtaac tttcccaatc aagactggtt ttaaacatgg cttaacacta 2691841 ggttaagctc cctttgctgt taatttttcc cggatcagcc tcttcagtcc ggttccctca 2691901 ccggaaatca caagtgtatc gccttcgtca atgactgttt cagagctcgg attcagttgt 2691961 ttatcctgat tctttttaac aattgcaatg accgtcacat gatattcctg acccacattc 2692021 aaatcaccaa tcgtctgatg aatggcaggc gctcccgcct ctgctttaca ccactctata 2692081 atcaaatcat caagggctga ctcgacctgt tctaatgctt tcggtttata tgccattccg 2692141 ccaagaattg cagacatttg ccttgcttca gcgtcatcaa actgcacgga ggcaacacat 2692201 tcctcatggt cgttttcgtc aaaatagtaa agctctctcc gtccgtcatg atgaatgata 2692261 attgaaattt tatcacggtt tctagtaatc atttcaactt tttgtcctat gcccggcagc 2692321 tctgattcgc gaaccctcat atataaaccc tcctacatat ctgaaaacca gccataaaca 2692381 cttttaacac catatatatg tttaaatgta agcgtatgtc attatagcaa atgtctattt 2692441 taagttcaat gaaacttcaa aaaacaggct gccctgcaga ggacagcctg atatttttta 2692501 ttgcgccgaa tcttttttca gttctcttcc tttccatgca agccaaattt gtgcggcaat 2692561 gtatagagaa gaataaacgc ctgttaacag cccgaccaat aaagcaattg agaagttagt 2692621 aatagaagat gctccaaaga tcagcaatgt cacaacaaca atcacaacgg ttaatacagt 2692681 gttaattgaa cgtgtaaagg tttgctgcag gctcaggttt acaatatggt tcagatcggc 2692741 aaaggttttc ggcttacgct ttttcatatg ctcgcggacc ctgtcaaatg taacgattgt 2692801 atcgttaatg gaatacccga ttatcgtcaa gatggccgcg atgaatgtaa catctacctc 2692861 aagccttgta atactgaaga acgtgacgat aaagaatgcg tcatatagca atgaggcgat 2692921 ggcagcaatc gccattttgt attcgaatcg gattgaaacg taaataatga tgccaataga 2692981 agctatagca actgcgtaca gcgcatttct cgccagctcc ttaccgactg tcggtgaaac 2693041 tgtgctgaca tttggatcag atccgtattt gtctttaaaa tacgttttta cttttgcaat 2693101 ggtttcttta tctggcaccc cgacaaaacg ggcaacaccg atattgctct tttcgcctga 2693161 cagaactaca gtatcagggt ccatacccag agattcaaaa tccttctcaa cttgctctgt 2693221 cgtcagctta tggtcgcttt gcacttcaat ccgtgcaccg cttgcaaagt caatgccaag 2693281 attcagcctg aacacaagca ggataataat cccggcaacc gtgaccgcac tggagaaaat 2693341 aaagaagtat ttgcgtttgc tcgtgaaatc ccatttttgg aatggcgtat gcggctctgt 2693401 attttcatcc gtatcctgaa tatccatgat atgtttctta ttgacaccaa accagccttt 2693461 tttccgatca agccatctgc tttccacaag gagagcgagg agaaatctcg ataagaaaac 2693521 ggcagtgata aagcttgtca aaatcgatag gatcagcatt gtcgcaaacc ctttaacaga 2693581 gcttgtccca aagataaaga gcacaaccgc tgcaataatg gttgtaatat tcgcgtcaaa 2693641 aatcgtcgca aatgaccgtc tgtttcctga acggaaggca gagcggactg actttcctag 2693701 cttgagctct tctttaatcc gctcataggt aataatgttg gcgtcaacag ccatcccgac 2693761 acctaaaatg agagcggcaa ttcccggaag cgtgagtacg gcattcatcc agtcaaagat 2693821 ctggagtgta atgtagatat aaacagacag cgtaatcacc gcgattaatc ccggcagacg 2693881 gtaatagaaa agcataaata agaaaataat tgcgataccg acaataccgg caaacaccgt 2693941 atcatggaga gcctgctggc cgaattgcgc gcctactgat gtcgaatact tttcagtcag 2694001 tttcacagga agtgcgcctg cgtttaaaat gctggctaaa tctttcgctt cttgagctgt 2694061 gaaatgacct tcaattttta catcagttgt atttagttcc tgacttacat ttggagcgga 2694121 tacaaattta ggatgctctt tttgaacttc tttcttaaag gaatcacctt tatcataatc 2694181 caaccaaatg acaagctggt tgtttggcgc cattttcatg accttcttgg tcacttcacc 2694241 aaatttatca gcgtctttca gcttaatcgt gacaattggc tcatttgttg tgctatcata 2694301 agtttgttta gcgccgtttt cgactagatc agcaccgttt aacagttcct tatcatttgc 2694361 atctctgaaa gaaagctgcg cttcagtcgc caaaatttca cgcgctctgt tttggtttgt 2694421 cacgccagcg agctgaacgc gaatccggtt attcccttca atttggatgt tcggttcgct 2694481 gacaccgaga acattggccc ggcggttcag tgcctctact gtgctgacca gaacgtcttt 2694541 tgtgattttg tcaccttttt ttacaggctg tacatcatac agcacctcaa atccgccttg 2694601 caaatccaat cctaacgtaa tattgttagc ggcaggcttc gtaaagtagc ccaagcccgt 2694661 gccgatcaat agaacgaaaa ggaaaaacgc aatcaagcgt ccttttttca ttatgtatat 2694721 cctcccttaa acctgtgcga atcaacctgc tatctcagca gttcttccaa tgcttcctgg 2694781 ccctcttcac tgcccagcca attagacgtt ttaaatgact caacggttgc atagttcata 2694841 aattcgccaa ttttcactga taaaatatca ctcgccagtt cataaatgct cagttccgtt 2694901 ttctttttcc acttcttatc tgttaagtat gaccacaaac tttcgagttc aacatcatca 2694961 tacccgagaa tcttaaactc ttccagtttg ctgtaaagaa acggcctgac gtggtcttta 2695021 tatagatcgg ctggatgctt ctccacgaat tccacgctcc ttttttattg tttttcaaga 2695081 agacttgtca tgcttggacg acatatacgc atatctttat tgtatatgat tccaggtagt 2695141 ttgagaaggc agggggtaaa aatggcgaaa cagacgtttt taaagggcac tcttatcctt 2695201 atcgcagcag gaatggttac aagaatgctc gggtttgtca accgggtggt tatcgcccgt 2695261 tttatcggtg aagaaggagt cgggctttac atgatggcag cgcctacttt cttcttggcc 2695321 actacattaa ctcaattcgg tctgccggtc gcgatcagca agctagtcgc tgaagccagt 2695381 gcgcgcggag atcatcaaaa aacgaaaaat attttagtca tgtctctgac cattacggga 2695441 gtgctcagcc tcatctttac accgctgttt ctgtttttcg cccctgttat ggctgaaacg 2695501 atgctgacag ataagcgaac actgtatccg ctcttggcca ttacgcctgt tgtgccgatt 2695561 attgctatat cgagtgtgct gaggggatac tttcaaggaa aacagaatat gaacccgctt 2695621 gctatgtcac aagtccttga acaggttgtc cgcatttcac tcgtggctgt ctgcacaacg 2695681 atttttctcc cttacggaat tgaatatgct gcagcggggg caatgctatc ctcagtggca 2695741 ggggagctgg catcacttct ttatttattc gtttgcttta agtataaaaa gacaattaaa 2695801 atcagaaagc attttttaca gtcaattaaa aacggaaaac aaacctttac ccaattaatg 2695861 agcgtgtccc ttccaacaac cgggagccgc tttatcggaa acctctcttg gtttttcgag 2695921 ccaatcgtcg tcgctcaaag ccttgccatc gccggtgtgg caacagttgc cgcaacaaag 2695981 caatacgggg aactaaccgg ctttgccatg acgctgctga ctctgcccag ctttattaca 2696041 tattctttgt cgaccgcgct tgttcctgcg atcagtgaag gaatggagca gaaaaaattg 2696101 caggtggtgg aataccgctt agaacaggcg atgcgtctct gtctgctcag cggaggcatt 2696161 tcagttgtta ttttatttgt atttgcggat gagctgatga gagtgatgta cggttcctca 2696221 ggcgcagctg tatttataaa agtgatggcc ccgttttttc tgctttatta tttccaaggc 2696281 ccgcttcaag ctgtgctgca ggcgcttaat ttggcaggag ctgcgatgat gaacagctta 2696341 atcggagcgc ttgtcaaaac aggccttatt tttgtccttg ccacaaggcc ttctcttggc 2696401 attatgggcg cggcattagc cattgtgaca ggcatggtgc tcgtcacgct attgcacgca 2696461 gcaaccgtaa gcaaagtgct gccgatcagc atcaaaatca aggagtacgc gctcagcttc 2696521 gctgttattg taatttgcgg attcatcagc tccgccatca aacaatatat aagctttgga 2696581 gcatctgagg ctgtcaatct agccggatgg attgcggcga gcgccgccat ttatatgatc 2696641 ctcctgctcg ttttccgttt aattaaaaaa gatgagcttc gccgcattcc cattatcgga 2696701 cggttgatca tccgataatg gtcacgtgcg gtgcccatct ttttcatcaa tatatatttc 2696761 tccgtctgta aacgagcaaa atgaaatatc tgaagggttt gtgtatccgt gtttttgcaa 2696821 actttcaagc agccattttc tatctttact gattctggac aggttttctg tttgaatgaa 2696881 gccgtctata atgagcggca tttcgagctg ccgatgctct ccgctgtttt ctttcttaac 2696941 aatagtcagt ttgcccgacg gctctaaaat agcaaatgat acgtcagcta ctctgtcgat 2697001 gctattttct ctgagctgaa ccattaaatc atcaaaatta taacgctgtg atttcatggc 2697061 ttcttcgtca atttttccat atttgataat tatggtcggc ttaccgtcaa gaagctggcg 2697121 gacttttcgg ttttttaaag aaaagtatgc caaagtcact tgaatgatca ttaatacaag 2697181 cattggcaaa atggtatgaa atagatgatc gtctacgttt tctatggcta aaacggcaat 2697241 ttcagccatc atgataaaga caacgagatc taaaatacta agctctccga tctcccgttt 2697301 gcccatgaaa cgaaaaatga ccaatatcac aaaatacaat acgactgtgc gaaacgcaat 2697361 agtgagaagc tcttccatta tgcacctcca actcattata ggttgcaaca aaatgatcaa 2697421 tttatgtaag aaaaaccgat tgcatttcac aaagctttta cgtctaattc atgggataag 2697481 ggaatacatt tttacaaaga cgagccatca gcatgtctga cggttttgaa caaaaagaac 2697541 agaagccttt taatacaggc agagaggaga caatcatgga ggaaacgaaa caagttggaa 2697601 aaggcattct ttacggctta atcgccatat tttcagccat gctcctgaca agtttagcgg 2697661 tttcactttt attgaccgca acctcgctgg aagaatcatc atttaactgg ctgatcaccg 2697721 ctatctcatt tctctcttta tttatcggcg ggttcatttc aggcgggaaa ggcaaggaaa 2697781 gaggctggat gattggcgca ttgaccgcct taagtttttc tctgattatc ttattgtttc 2697841 agtatttagg attcggaaag acatttacag cagaacagct gatcttccat ctgggatttt 2697901 taggggtgtg catgctgggc gggattttcg gcgtgaacat gaggggaaac aggtcttcca 2697961 cataaaaaag agcgggctca cttgcccgct cttttttgtt tgctatgtat agctcctgct 2698021 gttattcagc agcagaaact tctctgatcg cgcggcggtc gaacgtaaga cgtgtgttat 2698081 caccagtctt aattacgact ttgctttcgt cgatagagtc aacagtaccg tgcaatcccc 2698141 cgattgtcac tactgaatcg ccttttttca gttcctcttg catttggcgt acagcctttt 2698201 gctgcttttg ctgaggacga atcagcaaga agtaaaggac cgcaaacatt aaaataatag 2698261 gaaccaatgt acctaaagtg ccagtcatca ttttcacccc tttctgtaag cctgttatgt 2698321 ttatttagaa gcttttcgca tttggcttgt tatagccgta acgctcaaag aactcttctc 2698381 tgaaatcacc cagacgatcc tcgcgaatag cctgtcttac ctgctccatt aagtgtaaca 2698441 gaaaatgaag gttatggtaa gttgttaatc gaaggccgaa tgtttcattg cagcgaatca 2698501 agtgcctaat gtacgcgcga gtgtagtttt tacatgtata gcaatcacac tcttcatcaa 2698561 tcggacggaa gtctctttca aatttcgcat ttttcatatt gagtcgtcct tcagcagtaa 2698621 acactgtgcc gtttcttgca atccgtgtag gcagcacaca gtcaaacata tcgaccccgc 2698681 ggatcgctcc gtcgatcagt gcgtccggag aacctactcc catcagatat ctcggtttat 2698741 ccttcggcaa gagcggtgtt gtgaattcga gtacacggtt catgacatcc ttcggttcac 2698801 ctacagacaa tccgcctata gcatatcccg gaaaatcaag cgaaatcaag tccttcgcac 2698861 tttgtgtccg cagatcttca tattctccgc cttgtacaat accaaacagc ccttgttcat 2698921 cctgacgatt gtgggcattc aggcagcgtt ccgcccagcg gcttgtccgt tcaactgacc 2698981 tcttcatgta gtcgtactcc gccgggtatg gcgggcattc gtcaaacgcc atcataatat 2699041 cagagccgag tgcgttttgg atctccatcg ctttttccgg agataaaaac agcttgtctc 2699101 catttagatg attgcggaaa tggacaccct cttcctctat attacgaaac ttgcttaaag 2699161 aaaagacctg aaaaccgcct gaatctgtta aaattgcgcg gtcccagttc ataaatttat 2699221 ggagcccgcc cgcttctttg acaatgtctt ggcccggacg aagccataga tgataagtgt 2699281 tgctcaaaat gatgcctgca tccattgctt tcagctcttc aggcgacatt gttttgactg 2699341 tcgccagtgt gccgaccggc ataaaaaccg gcgtttcgaa ggagccgtga ggcgtatgca 2699401 ctttgcccag ccgcgctcct gtttgtttgc attcttttat aaattcatag cgtattggtt 2699461 gttcagccac ttttgatgag gcctcctgtt ctcaaattat ataatcagca tcgcgtctcc 2699521 gaagctgaag aaacggtatt cctcttccac tgcatggtta taggcacgca gaatgttttc 2699581 tcttccagca agcgcgctga ccagcataat caatgacgat ttcggcaaat ggaagtttgt 2699641 aatcattccg tcaatggctt taaattcata gcccggataa ataaaaatag atgtccagcc 2699701 gcttgatgct ttaaattgcc cgtcatgttc tccggcaatc gtctcaagcg tgcgtgtcga 2699761 ggtcgtgccg acagaaatga tccgaccgcc attttctctt actttgttta aggctgcagc 2699821 cgtttcttct gacatttgat aaaactctgc atgcatatta tgctcttcca cttcatcggc 2699881 actcacaggg cgaaacgttc caaggcctac gtgcagtgtg atgaactcaa tttgcacgcc 2699941 tttgtctttc agctgctgta agatttcttc cgtgaagtga aggccagctg taggcgcagc 2700001 agcagagcca atttcttttg aatacactgt ctggtagcgc tctttgtcat caagctgttc 2700061 tttgatatat ggagggagcg gcatctctcc aagggattca agcacctcgt agaaaatacc 2700121 gtcatattga aattccatct ttctgccgcc gtgctcaagc tcttccgtgc agattgcctt 2700181 caatcttccg tctccaaatg tgacaacagt tccttttttc acccgtttcg ccggtttggc 2700241 aagtgtttcc catttatcac cggtttcctg tttcaacaaa agaagttcca ctttcgcgcc 2700301 ggtatcctct tttgtgccga ataaccgcgc aggcagtacc cgggtattgt tcaggactag 2700361 acaatcgcct tcgttaaaga agctgataat gtgtttaaac gagctgtcag taagctctcc 2700421 tgtatgttta tcgagcacca tcagccttga agcatcacgc tgctccaacg gtacttgtgc 2700481 aattaaacgt tctggtagtt caaaatcaaa taaatcgact ttcatgatga tttcaccttt 2700541 attctagtct tttgttattt cattctgcca aaaagattaa gcaaaattga taataccaca 2700601 cttataataa tacaagtgac aaccgggaag aaaaacgtaa catttccttt ttttacaaaa 2700661 atatctcccg gcatcttgcc gacaaaatgc aaaactgctc cgataataag caaaacagca 2700721 ccaagaatca taatgatctt aggaaattca gtcatatcgg ggagcctcca tttggaaatg 2700781 atgataaacg gccggtgtca cgatccttcc acgcggcgtt ctttgtataa atccaatttg 2700841 cagcagatat ggttcatata cgtcttcaat cgtatgcgat tcctcgccga tggtagctga 2700901 aatcgtatca aggcctactg ggccgccgtt gaatttttcg atcatgccca tcagcagctt 2700961 atgatcaata tgatccaaac cgaggcggtc aacctgaagc cgctccagcg cattctgaga 2701021 aatgtcttcc gtaatcctgc tgtcacccag cacttgggcg aaatcgcgca cccttctcag 2701081 caggcggttc gccacgcggg gcgtccctct cgatcttctt gcaatttcaa gagccgacgg 2701141 tttatcaatc tcaacctcga atacatcagc ggttcttgtg acaatatccg ccagttcttc 2701201 ttgtgtatag tactcaaggc gagacattac gccgaatctg tctcttaaag gagccgtcaa 2701261 aagccccacc ctcgtcgtgg ctcccaccag cgtaaaaggc ggaaggtcga ggcgaaccga 2701321 gcgggcagat gggcctttgc caatcacaat gtccaggcaa aagtcttcca ttgcaggata 2701381 aagcacctct tcgatcgatc tgtgcagcct atgtatttca tcaataaata atacatctcc 2701441 cggttccagc gccgttaata tagcagccaa atcaccaggc ctttcaatcg caggccctga 2701501 tgtcgtccgc aattccactc ccatttcatt agcaacaatc gaagcaagcg ttgtttttcc 2701561 gagtccgggc ggcccgtaca gaagaacatg atccagcgtc tcctgtctca ttttcgccgc 2701621 atctataaac acgcgcaaat tttcttttac cttatgctgc ccgatatact gtgccagatt 2701681 ttgcggcctc aggctttgct ctatcactga ttcatggttg tctgcttcac ttgagacgag 2701741 ccgttcatcc atgaacatca ccttacttta atagtttttg taatgctttt ttcacatatt 2701801 ggtctgttgt cagcccaatt tcttctttaa ggtgaggaag cacctttttg atttcttttt 2701861 cagcatatcc gagaaccctg agggcttcaa gtgcttcttc aagagccgtt tccgctgttt 2701921 gcttttcaag cctttcttca tgattaaaca gattttcaat catttcaggc acaacatctg 2701981 ccagctttcc ttttaaatct agaataatct ggcgtgcggt tttctttcct actccaggaa 2702041 acttgaccaa aaaagcttca tcttcatttt caattgcttg gatgaccgct ccgggatcac 2702101 ccgagcccaa gatggcaagt gctcctttcg ggccaattcc ggtcacgttt aacagctttg 2702161 taaagagcgc cttctcctct cttgttgaaa aaccataaag cgaaaaagca tcctctctga 2702221 tatgatggta tgtaaaaatc gtttcttggc ttctctcctt atatataaac ggattcggcg 2702281 tgaaaatctg atagccgatg ccgccgttct ctatgacaat atattgggga gatacataat 2702341 caatcgtccc tttaacaaat tcaatcacgc aaattcacct ctttgactgt tcttcattgt 2702401 accataaaaa cagccaaagt cttatagaaa agttaacata tgttcgcttc tctctcattc 2702461 tttcacgaaa aaaaagacat gaatacatgt cttcaatcag cggacgctac ccgctgtatg 2702521 tcttcatatg ttcgatgaca tcctcaaact ccgcttttgt ccgaaatgga atgcctttca 2702581 gcagattttt ttgcatatgg ctttccagcc tttctaaatc aatttgaaaa aaagactgaa 2702641 ttggttcgga agctggctca ggccgcccat gaaaagtgga aatcactcca ttatccgata 2702701 caccgatata cccgttgacc ttgctgagcg gagaaatatc gtccatttgc ttccggaaga 2702761 gcacatatcc ctttttttgt tccactagcg tccatccggc ataagctgcc caaaaatcat 2702821 ccatagaaaa cactttttca tgcttatgct caatgctgac atcgccgtcc aaatacacct 2702881 tttcaagctg cacatgcacc tgcagcggct catagtgctc cacttccgcg ccaagtgcgc 2702941 gggaaggagc tcctattaaa aatactgccg ctgagcaaag aatgcccagc aaaagatacg 2703001 ccgtgctgaa tcgtttcacc ctctacacct ctttgcacac gtttatgatt agtttgacca 2703061 aagaggctac tgcttaaccg ttttatcaaa atttgtctgc acattttccc tgacaaaccg 2703121 ttcctccgta tacacatctg tgctttgctc agaaattgtc aagaatcgcg tcagaaaggc 2703181 actgaaaaaa tacaatgccg caaagatcca aatcacgcca cctgcaccga gcggcccaat 2703241 gaaaagactc acgatgcccg gcgcgataaa cgcacataaa ccagatccca aattcaacac 2703301 tgacatggca gcacctttat tatcaggtgc aagcgtcggc aaaagcgcgc ttaatgggac 2703361 gtaccctgct aaagccgcgc cgtagcagca ggcgataatc atgagcaccc aatactgatg 2703421 cccgatcagc tgaggcgtgt aatacagcgc cagcgtaaaa ataccgcatc cgacaccgcc 2703481 aaaccacatg accgtattgc gccagcctag tttatctccg actgcaccga aaatgatatt 2703541 aaacacaata ttcacaaaaa acagcgtccc ccatatttgc agccattccg aaaccgaata 2703601 cccgtatcgt gctaaataag taggaagaaa gatggcaaat ccaaattgtc ctatcgcatt 2703661 aatcgtcttg accactccgc cgatgcctac cttagggttt tcaaacataa tcgtaaatgc 2703721 cttcgacagt tctttccatt tcggctgatc ttgtttttgt atcggagtaa atttatcttt 2703781 gttaaaaaat aaggcaagaa ttccgcctgc cgccacaaac agtaaagcgc tccaaagcgt 2703841 attgatttct ccaaaggccg gaactgcata gctggaatag aacggaccga gcacgttaag 2703901 gccgcacgta aacataaacc aaaaccagcc gacggctttt ccaagaatat tttgagaggt 2703961 gctgtatgac acccatacga gaaaagagta tgcaaacagc ggatatccca agcctctaag 2704021 agcatagctg cccaagagag ccggataata catatgagga atcgcccagc cgataaaagc 2704081 ggccgaaccg aggataaatg caagcaatcc gacagtcatc gtttttctcg gcccccaagt 2704141 ttggacaaac gttcctgaaa gccaagctga gatggtgaca gcaatgccgt acatggtaaa 2704201 taacgatgcg gattgctgca tactgagacc atgatcaacg agaaaaggag acagccagcc 2704261 ttgttcgagg ccgtctccaa ccataaagat gacaacgcca atataacccc aaaccatgtg 2704321 agaaggaatt ccgattttgt tcaaaacatt tcctttagca tgtactgtat tcattttctc 2704381 caccgcctac ttaaagtatc aatggagtat atacccaagc ttgctgaatt gtaatcctgt 2704441 tagattaaaa agcgattttt tcagtgtgct caatgctaac aggcatgcca aaagcaagcg 2704501 attgctgtgc tgctctggcg atcctcccgg cctgtaaacc gtcattgccg gtgcagggag 2704561 tctcctggtt tgtgccgatc gcttctgcaa aacggagaat ctcctcctca tatgaatcct 2704621 tatagcgttc aaggaaaaag aaatgcggtt tatccttcat cacaaaatca gctgttgaca 2704681 cctcaaccgt tgtcggcctg ctattgtcag ccgctgcaga gcctttcgtc ccgaaaacct 2704741 caacccgctg gtcatatccg tacacagctt ggcggctgtt atcaatcaca gccatggcac 2704801 cgttttcaaa agtcagtgta ataacagctg tatcaatatc acccagctcc gcaaaagaag 2704861 gattcaccaa agccgcccct ttggcataca cttccgtcac ttcgcttccc ataatatatc 2704921 tggccatatc aaaatcatgg atcgacatat ccataaacaa tccgcctgac gtacggacat 2704981 aatctatatt cgggggttct gggtcccggg acgtgatttt taataaatga ggtgtaccga 2705041 tttcaccatt ttcaacaatc gttttgattt tcttaaaatg aggatcaaag cggcggttaa 2705101 atccgacttg aagtgttacc ccgtgtttcc ggacagccgc aagcgcttca ctcgtttcgt 2705161 ccagagagaa actaacgggc ttctcacaaa atatatgctt tttcgcctcg gctgcttctt 2705221 tgatcatctg tgcatgtacg gctgtaggag agcaaataaa aatagcatca atatcaggat 2705281 catgtaataa atcacgataa tcagaggtta tgtattcaat ctgatgactg tcggcccagc 2705341 tttttatacg gctcgcctga atgtcagaga ttgcttttat tttcatgtga ggaatccggc 2705401 ttatattttg aacatgaagt ttgccgatgc ggcctgcacc gataatccct gtcacaatct 2705461 gttttgtcat ggcttcttcc cccttgatca ttcacgaaag cgctttattt aaaattaata 2705521 ctatcccatt tgtaagcgct tttcaagaat ggaaattaaa cgttctatgt ctcttttatc 2705581 acaattcatg cttataagta gccttcttct tcaagaccag atacactaga attaggctct 2705641 ttttcctgaa cagtttatga ttttcctata aacagctgca taaaatagag caaagaaggt 2705701 gaatgaaatg ctgacaaaag cagaggcact ggcccatacc gtcatatacc gcaagaacag 2705761 cagatttgat aaagtcaaag agaaatccga ggaattaaca ctaatcggca agggaagaag 2705821 cgcctatgtg tttgccttaa cagaaggcgg tcgaaaaatg gcgctgaaag tattttttcc 2705881 ggaatatcaa gcgacagcag tcaaagaagc agcgatctat gaaaaattag ccgggtccgc 2705941 attctatcct gacatttacg aaactggcga ttcatttatt ctcatggaat atattaaagg 2706001 tgaaaccttt tataactgtc tgaagaaagg cattgcaatc agtgatgaca tgattcagca 2706061 ggttgaagaa gcgctttctg acgcccgggc agccggactg aacccgtcag atattcattt 2706121 gcggaatctg atattgacag aaaccggggc ggtgcgggtg attgatgttg cgagatttga 2706181 gcagacaaaa acatgcacgc agtgggacga cttaaaatcc gcatatcatg cactctacaa 2706241 aaaaccgata ttccccaaaa agattccggg tttttggctg gagatcatcg catttttata 2706301 taagaaagat tggtttcaaa agcatttcgc acagcggaaa agaaaatatt cttaaatcaa 2706361 aaaggcagcc gcacaagcgg ctgcctttat catgtatttt ttactttctg acggcagaaa 2706421 tcagtttcat ttgttcaggc gacagcttaa ttcgatagcc tctcacagtt aagtagaccg 2706481 cttctgggtc cttctcgccg gaatgacaat acgttttttc catttctgtc tcccctcacc 2706541 ctttattggc tttatttcat cttatcattg ctttattgag gtaattttaa agaaatgtaa 2706601 agattatatg aatccgatat atagtaaaat gagagaaaaa aagggagaga gtcacattaa 2706661 gaccgaaaac accttgagct tagatgcagc cagaggtgaa cttgtaaatg aaaaaacact 2706721 tgtcaagaga acaatctact ggaattaccc ggacagccgc ccagcagtga cgtggatcaa 2706781 tcacaataca gtgaaaatcg gcaatcagac tttacatctt gatactgatg aaacgtatga 2706841 ttggcgaaaa gatgatcatt ggatccgtga agaaccgccg caggcgtcag tgaggtgatg 2706901 aaacatgaat aagatgaacg gaacaaatga tgaaaagcat ttcaatcatt ttgtgattgc 2706961 tttatccttt atatacggtt tgactgaact aggctatttg ttgctgaagg attttataac 2707021 aattgccata agtttgcctc tgtagaaaaa cgcagcgtag tcgatacgcc gcgttttttc 2707081 tttttccctt cctcttctta ttgataatta caggtcatat aatgtgacaa atcgattgta 2707141 gaaatagttc gattagacca aaatcctttt tatacatgta ttcgaatttg aagtgagggg 2707201 gaagcttgat ggcagatttt gttgctagtt tgaatgcggt cttatggagt acgcccgtca 2707261 tttatatttt attgggaatt ggattcgcct tttcaattat gacccgtttt ttacaagtcc 2707321 gacatttaaa agaaatgatt gttcagatgt tcaaaggcaa gagctctgaa gccggcgttt 2707381 catctttcca agcgttatcg attgcgctgt ccggccgtgt gggcacagga aacatcgcgg 2707441 gagtggcgac agcaattgca ttcggcggac ccggtgcagt gttctggatg tgggcgattg 2707501 cctttatcgg ggcggcgagt gcctttgtag aatcaacgct tgctcaaatt tacaaagtga 2707561 aacaagacgg tcaatatcgg ggcggccctg cttattatat agaaaaaggc ttaggcatta 2707621 agtggtttgc cgtcttattt gccgctgctg cccttattgc aatggccttt ctaatgccgg 2707681 gcgtacagtc caactccatt gcggctggga tccaaaatgc attcggcatc tctcctttcg 2707741 tcacagggtg cggtctggtt ttattattag ggttcattat ttttggcggc gtcaaacgaa 2707801 ttgccaatgc ggcgcaaatg attgttccat ttatggccat tggatatatc ctgctgtctt 2707861 tgattattat tgtcatgaat gtgtctgaat tgcctgctgt gatctcatta atattcaaaa 2707921 gcgccttcgc attggattcc gcttttggcg gcttgatcgg tatggcgatt tcctggggcg 2707981 ttaaacgtgg catttactca aacgaagccg gccagggaac aggcccgcat ccggcagctg 2708041 ctgcagaggt ttctcatccg gtcaagcagg gactggttca ggcattttct gtttatattg 2708101 acaccttgtt tgtatgttcc gctacagctt tcatgatctt gtttaccggc atgtacaata 2708161 cccaggctgc agatggttcc tttatcgttc accagcttaa aggcgtagaa gcaggacctg 2708221 gtttcacaca agcggcaatt gacagtgttc ttcccggatt cggtgcaggc tttgttgcca 2708281 tcgctttatt cttcttcgct tttacaacaa ttatggcgta ttactacatc gcagaaacaa 2708341 atatcgccta tttagcacga ggcagagaaa gcaaatgggc gatgcttggc ttaaaactga 2708401 ttattttagc cgccacgttc tatggtactg tgaaaacagc ttcacttgct tgggcattag 2708461 gggatgcagg gcttggcatt atggtatggc tgaacgtcat tgccattgtg ctgcttgcca 2708521 agccggcgct ccttgcttta aaggattatg agcgccaaaa gaagcagggc ttagacccga 2708581 tctttgatcc aaaagcgctg ggtatcaaaa acgctgattt ctgggagaaa gaatacactc 2708641 atgaaagtga acgtgtctcc tgaacatact aaaaccggcc cgatatgacc tcgtgccggt 2708701 tttttatgaa cgatagtttg tatacacttc ttgaacatca tcgtcatctt caaggacgtc 2708761 tattaatgtt tccagcttct caacagcctg atcatcggct tctgcatagg tattgggaag 2708821 catggtcacc tccgccgaag aaattagata tttcgattcg agggctgttt tcacctcttc 2708881 aaaatgctca ggctctgtga aaacctcata taggtcttct tcaattcgca gctcttctcc 2708941 tcctgcttca agcacatcaa gcatgagctc atcttcttct atttgccgtt cagtacggtc 2709001 tatcgtaatg aacccctttc gttcaaataa aaaggctaca catccgcttt ctcccagact 2709061 tccgccattt ttattaaagg ctgtccgcac atttgacgcc gttcggtttt tattatctgt 2709121 tacgcattca accatgacgg caatccctga agggccgtag ccttcatagg tgatttcttc 2709181 atagctgctt ccgtcttggc ctcccgcagc ttttttaatg gcccgatcta tattttcatt 2709241 cggcatattg gcgccttttg ctttttcgat gacaagacgc aatgctgaat ttgcttctgg 2709301 atccgctccg ccttctttcg ctgccacata gatttctttt gccagcttca taaatatttt 2709361 cccgcgcttt gcatcctgtg cattttttct tttttgaatg tttttccact tggaatggcc 2709421 tgccatgttt tcaccttctt ttacattttc tatgtacact ttaatgggaa atgttcgctg 2709481 atgcaaagaa aaaggctgcc gaatatcact tccggcagcc cttccttcct agcggttgtt 2709541 cattttatga agttttctga acagcccttt atctgttgat acttggacgt cacggccatt 2709601 tgcatagttg cgcgctgctt ttacaacatt atctctgtca gactttgtga actctctgtg 2709661 gcttttgact gcgataacta ctcggtcatc cgataccata acttgtgtgt cattgacgtt 2709721 tttcacttgt ttcacacggt tggcaatttt tgcagccagt cttctgtttt cttggttgtc 2709781 atacccgttg ttcgctgcat tccgattcat gtttcggtta ttcgtgttgt tatatgttcc 2709841 gtcagttgcc aaaggaacac gatcgtcagc agtaacacgg tcacggttat ttacattcgt 2709901 ggtgtttcgg ttaccgtcgt tctgatcctc cattaattca gaaacaggac catcgtggtc 2709961 gattccgtct ccctgtctat cggcgtcatt ttcatttgta taatatccga ttggacgggt 2710021 attgccgtta ttgcgcgtat cattcatagc attatcgttt gctccgcatg ctgttaagcc 2710081 ggctgtcatt agaatcaggc tagcgatcgt cattttttta cccaatggaa aaaccccccg 2710141 tggacgaatt gagcatgttt gctcgctttt atcatgtgcg tatggggggc atgttaagcg 2710201 tgtcagttct ctccatttgg cagtgatctg cttgaaaaca aaaaaaggaa cgatttacat 2710261 cgttccgaac gatcactcat tttcttcttc cggacggcca aacatttggt ttacagaagg 2710321 ctggttcgtc attggcatag aaactcctgc cgaatatggg tttggatttg ggttagctgt 2710381 gccatatggc atattagggc ttccataagc tcccattccc gaatggccag gtgcagagaa 2710441 atatggctga tgatcaccgt cacagccgca gtcgtcatga tctttgtatg gcatgtaacc 2710501 atgagccgca gcaggctggt atgctcccat tacttgggga gtgccgtaat aagggccata 2710561 cggcatatgt ccatacggag atccataagc cggagatgcg tattgcggcg caccgtatga 2710621 accgtaatgt ccgtgatggc tgttttcatg atgctggttt tcataacccg ggtcatactg 2710681 aggcgataca aagcctggct ggtatccatg catcggatgc attggataag cttgtgccgg 2710741 atagtacgga tagcataatc ctgatcctgg aagaattggc gaaacaggca ccggacacgg 2710801 tacgaaatga gccggataat gataataagg ctgaacagcc ggcatcggca tattcggaac 2710861 tgtgtgatga acgttttcct cttctatacc gcctacctct ggcgcctttg gcatattagg 2710921 catattcgga taatttgcat tttccatatt actcatagcc tcctgttgtg gaaattggtc 2710981 ttgcatatga tacatatgat ccatatttcc gtcatgatgt tttttcggct cctccggttt 2711041 aggaggcgac caaggctgga aaagctgttt catatcataa taatcgttca catcagcttc 2711101 agggtacaca ttttcctgca aattaggcat cggcgggaca tacggcatgg acttcttttc 2711161 tttcggcttt gtgtcttcta catcgacaac ggatttaggc ttctctttcg catatggatg 2711221 ttcttgcttc acactcccgg ccgcaggact tttgcccgct tttggctctt ttctgaccgg 2711281 gactccttct gacggcactt ttattttcat tccaggcatg attaagtctg gattgctaag 2711341 ctgtgtattg agttttttca cttcctcaac atcgactccg tacttttcag ctattttcca 2711401 gagcgaatcg cctttttgaa cgatatggat tttcaacgtt ttcccctcct atgcaaaacg 2711461 tgaacagttc agctgtgatt acaatatgtt tcttcacaac atatgcctga acaaaagaag 2711521 ttatgagtaa aggaagggaa aatatttctg atctacgtga tcgaaagcat tcgattcagg 2711581 gcaaggagtg catcttcctg aatggctttt ggcaccttga tgacgcctga aggttctcct 2711641 ttttcaattt gttccagcga ccacaacaaa tgcggcaaat caattcggtt cattgtcagg 2711701 caagggcaca tgtcagggtt gagtgattcg atttgtttat ctggatgctc gtgaatgatc 2711761 cgctgaacaa gattcatttc tgtcccgatt gcccacttgc ttcccgccgg agcctggttg 2711821 attgtgtcga taatatattt cgttgatccg ttatcatcgc ttagtgtcac gacttcgtgt 2711881 gaacattccg ggtgcacaat gatctgaatg tcggggtctc gctctctcat atcatggata 2711941 tttttagtgg tgaatttctc gtgaacagag caatgccctt tccacaaaat cactttcaca 2712001 ttcgtatgcc cggattcagc tactaattca tctttcatcg gatcccacac agccatatct 2712061 tcaagcgcaa tgcccagatc ataagccgta tttctcccta aatgctgatc aggcaaaaat 2712121 aaaattcttt ttttctgtgt aaacgcccat tcaagcactt ttttcgcatt cgaagaagtt 2712181 acagttgctc cgccatgctt tccgacgaat gccttgatct ccgcagtgga gttcacataa 2712241 gttaaaggta tgatcgtatc tccaaatata tgctgaagct tcttccatgc cctattggtc 2712301 tgctgcatgt cagccatgtc agccatagaa catccagctc tcatatctgg caggacgacc 2712361 gtttgctgct cgcttgtcag catatcggcg gtttctgcca taaagtgaac gccgcaaaat 2712421 acgatataat ccgcttcttt gtttttttcc gctacttggg ccaattgcag ggagtcgcct 2712481 gtttggtcag caaattgtat cacttcatcc ttttgataat gatggcctgg tataaagagc 2712541 ctgctgccga actttttctt aatggcggca acgcgcgttt ccatatcctt tctcgatagt 2712601 tctttataac tttcgggcat catatcattc gattgtttga tcacatcaag aattgacata 2712661 acagcattcc tccacagatt catttgataa cgtaacatcc atgctgatat ctaaactttt 2712721 gacggaatga gtcagaaatc ctaatgaaat ataattcaca cccgtccctt taaaagcagg 2712781 caaagattct aacgtaatcc cgccagaggc ttcagttttt atattagccg gtgtgagctt 2712841 tgcaaaatga cggaccgtat caggcggaca gttgtcaaac ataataacat ccgctccagc 2712901 tgcaattgct tcccgcagct gttcctccgt ttcaatttcc acctcgatat ttaccatgtg 2712961 ccctgcggcc tgacgggctt ttttgcacgc ctctaaaata gagccgcatg ctgcgatatg 2713021 attatcttta atcatgatgc cgtcatacaa accgaatcga tgattatacc cgccgccggc 2713081 tctgacagca tatttctcca gcattctgag ccccggtgtt gtttttctcg tgtcacaaat 2713141 tttaatctgt tcatcatcca gacaccgaac agcctctctt gtcattgtcg caattcctga 2713201 cagcctctga ataagattta atacgacccg ctctcctgaa aggagcgcag ctgcgggacc 2713261 gtgtaactcg gcaatcactt cacctttatg caacatgtcc ccatcttttt tgtgtaaaat 2713321 gctttgaaca ttttcgtcca ataacgaaaa gccttctttt atgatcgctg ctcctgcaaa 2713381 aataccctct gactttgcaa caatctccgc ttcacagctc tgttctccaa aaatagactg 2713441 cgatgtaaga tcccctgtcc caatatcctc aagaaaaaag tgattcagta attttttcag 2713501 ctgtaaatga ttcattgttc caaatcccct cgttttttct gatcttcgtt cctttttttg 2713561 tatggacaat ttgtcttcct tgccagctca cctcagcatg aggaaaatcg gtgcggaagt 2713621 gagcccctct gctttcctcc cgcaaaagcg cagaaaacgt catcagcttt gcagtttgcc 2713681 atagatgaga aagttccatc tgccgaattg tgatatcctt cacatttact tcctgaaaag 2713741 gcagcgtatg aagccagatg ctaagctcaa tcaaactgct ttgttcccgc agaatagaca 2713801 tgtggcttgt cattttgctt tgcagttcat gcccctctat atccggcacc tcgtagaaga 2713861 cactggtttc tagccctgat tgatattgcc tgttataaac cggtttttgg ataatatgct 2713921 ctgctgccct ttttccaaat accagcgctt ccaataaaga attgcttgca agccggtttg 2713981 ctccatgtaa accggagcat gctgtctcgc caatcgcata aagccccggc actgtcgttt 2714041 ctccccagcg attaactgaa acacctccca ttaagaaatg cattcccgga gcaacaggaa 2714101 tttttccgct gtggatatca atccctgctt tttcacaaat agcggtgatg gtagggaaac 2714161 gcgtttcaaa atcagaaatc gcactgaagt ctatataaac gcgatttcct tttgccattt 2714221 cttcgtgaat aacccgtgag acaatatctc ttggagccag gtcacctaaa ggatgccgtt 2714281 cagccataat cctgcggccg ttttcgtcta ctaaacatcc gccttcccct ctgacagctt 2714341 ctgaaacaag cccgtaggaa acaccatttt tcacaagcag tgtcgggtga aactgagtaa 2714401 actccaaatc cgttaattcc gccccggccc ggtaagccag agaaagaccg tcacctgtga 2714461 cagtgagatc attcgtatgg tgaagaaaca ggtttccaca gccgccggca gccagcacaa 2714521 cttcgtctgc gtgccttacc ttgagccgcc ctttgctgtc ttttgtcatg acgccgatac 2714581 atcgtccgtc ctctataagc aaatctgctg ccgtttcatt ctcgattaac ttgattttgc 2714641 tgttgatccg tttgagcaaa taatcgataa gcagcctgcc tgttgcgtct ccgcctgcat 2714701 gaaatatgcg gttgtatgag tgggcccctt ctcttccaag acaaacaccg cctcgttcat 2714761 tgcggtcgaa tggaaatcca cgctccaata ggctttgaac catcattttt ccatcatgta 2714821 atacgtctgc tacaatagct agattattat ggccgcaccc tgcgtataac gtatcctcca 2714881 gatgggcttc aatcgagtca tcttttgcat aggccgcagc aatcccgcct tgtgcataga 2714941 cagaattgct gtttttgacg cttttttttg tgataacagt cacttcgtat gagggcggga 2715001 aagctgcagc taaggaaagt gccgccgccc ctgaaccgat gactgcaatc gtctttttag 2715061 acatatgcca tcctcctgtt gtttacacct gtcttgacac ctatatttac acaaggataa 2715121 aataaactca agagtttttt atggagaacg gatggaggaa gaccggatga tttatttaga 2715181 ttatgcagcg acaacgccta tttgtgagga agcccttact gtatatcaga agcttagtat 2715241 ggatatgtac ggaaatgcca gcagcctgca tgatgcagga ggaaaagcaa agcacatact 2715301 ggagtactgc cgtgaaaaaa tcgccaacat cattggcgga gaagcaagcg gcatctattt 2715361 tacaagcggc ggcactgaat ccaattttct ggccattcaa tcattgttaa acggcctgcc 2715421 aaaaacgaaa agacatttta ttacgactgc catggagcat cagtccattc ataattgcgc 2715481 tgcttttttg gaacagcagg gatatgatgt aacagtcatt gaaccgaatg aatacgggct 2715541 tattaccgag gaaatattac taacccatat ccggccggaa acaggccttg tatctattca 2715601 gcatgcaaat tctgaaaccg ggatcattca gcccattcaa cacctgtctt catacctgca 2715661 caataagggg attcttcttc attgcgacgc tgttcaaacg tttggaaaga tcccgatcaa 2715721 tacaaaaaat ctgggagtag atgcactctc aatgtccagc cataaaatcc acggtcctaa 2715781 aggagtaggg gcggtctata tccggccgga tgtcccttgg aaacccgttt atcctctgac 2715841 tactcacgaa tacggattca gagccggcac cgtaaatgtt cccgggatcg gtgccttcac 2715901 tgccgctgca gaattgatcg taagcgaaat ggaaaaacag atatcccgca atgaggcatt 2715961 aagaacatac tttctagacc aaatccgtat tcggtctctc cctgtaaccc ttgcagcaga 2716021 cacttcgaaa gcagaatgtc ttccgcatat tatagggtgt ttttttcact catttgaagg 2716081 acaatatgtt atgttagaat gtaatcggag taatatttgc atttcaaccg gcagcgcttg 2716141 ttctgcaggt taccacggtc cgtctgaaac aatgaaagca ttaagaaaaa ccgaacaaga 2716201 agctctgcaa tttatccgca tctcttttgg caggcataca acagctgaac agctggaaca 2716261 gttattacat acgtttacag tgctttggga acaaaagaaa ggagaatttg atattgaccg 2716321 aagaattaaa gctaatgggc gccaacaggc gtgaccagct tcttctgtgg ctgaaggaat 2716381 ctaaatcacc gctgacagga ggagaactcg caaaaaaagc gaacgtctca agacaggtta 2716441 ttgtacagga tatatcgctc ttgaaagcga aaaatgtacc gattatcgcc acaagccaag 2716501 gatatgtata catggatgca gccgctcagc agcaccagca ggcagaaaga atcatagcat 2716561 gtctgcacgg tcctgaacgg acagaagagg aactgcagct catcgtcgac gaaggcgtta 2716621 cagtaaaaga cgtaaaaatc gagcatcccg tatacggaga tttaactgca gccatccaag 2716681 taggcacccg gaaagaagtt agccatttca tcaaaaaaat caattctacg aatgctgcct 2716741 acttatcaca gctgaccgac ggcgtgcacc tgcatacact gacagcacct gatgaacatc 2716801 gcatcgatca agcctgccaa gccctcgaag aagccggcat tttaattaaa gactaaaaaa 2716861 agccctctag tgggcttttt ttataattgg taagactggt atgcacccag aagcctcact 2716921 ttgcagccga gtgcttcaag ctcctgcatg gcccctggaa tcaatacatc atcaaacgct 2716981 ttctcaatat caataataaa gaaataatgg cctaatccgg ttttagtcgg acgtgactca 2717041 atttttgaca ggtttaaatt tctccaagaa aatgcagaca gcactctatg cagcgccccg 2717101 gactgatcat cctgcggcag catgaccatt aaggtcgttt tgggcctaga gctcaatttt 2717161 gaattcactt caaaagatat gttttcatcg ggagacagga taacaaatct tgtatgattg 2717221 tccctataat cctgtatatc ccgtttcacg atttttaatt cgtatgtaga agctgccata 2717281 tcattggcaa tgaccccgat attcagctcg ggatggtcac tgacaaactt tgctgccgcc 2717341 ccggtagaat tggcgtattc atatggaacg gaaggaaaat gtcgatgaag aaatttatgg 2717401 cattgcgcaa tcgcgtgtga atgtgagtaa attttgtcga gctctttcca tgcattctct 2717461 cttgagggat ggacgagcaa gtgctggtga atcggcaacg tcatttcacc cacgattggc 2717521 aaaggctgtt catgtattaa atagtctatt gttagattaa cagatccttc taaagcattt 2717581 tccaaaggaa caaaagcaaa atcaacttcg cctgcaacgg ctgcatctat acactccgga 2717641 atggtgcggt aagcaacatg ttcggcgccg ttttgaaaac aagaactgac tgctagatgt 2717701 gtaaatgtag ctgctggacc taaataaccg actttcatga cgattttctc tcccttatgc 2717761 acctgaacct aatatttcaa ccttttctac aaaatcaaac ttcctgagct tattcattaa 2717821 tgtatgaatg tcttcttcca ttgccgacgt actgatagac agtgtcacat ttgctctgcc 2717881 ttgaagcgga atggtctggt gaatggaaag aacgttgctt ccagaatcag ctaccgcctg 2717941 aagaagctga gataacgcac ctgacctatc ctccaaatga aagaaaagtg tgataatttg 2718001 ttcttttacc atggtgtaga atggaaaaac agcatccctg tatttataaa acgcacttct 2718061 acttaaatcg accttttgaa cggcatctgc tactgaatct gctttttttc gatcaagcag 2718121 ctttttgact tctaatgttt ttctcattgc atcgggcaat acatcttcac ggacaagata 2718181 aaatgtctcc tctttcattt gcatcccccc tttaaaatag agagcctggc accaggctct 2718241 cttttcagcc aacattgatt aatcaataaa ttcaaattca aattccagaa gcctgattat 2718301 atctccatcc ttggctccgc gttctctgag tgcttcatca acacccattc cgcgcatctg 2718361 tcttgcaaac cgtttaaccg attcatcacg tgagaaatca gtcatcttga ataaccgctc 2718421 aaggctgtct cctgaaagca caaatacacc gtctggatcg cgtgtaatgt taaatggcac 2718481 ttcttcattt tccatcgtgt acatgacacg gttttgtgta agctcttcct cgtcatacag 2718541 cgggaattcc ggtgtgttct caagctgatt ggcaacctca aacagaagct cacgcagacc 2718601 ttctcttgtc accgcactga tcgggaatac cggataatca tccgtcagct tttctttaaa 2718661 ggcttcgaga ttttccgcag cctccggcat gtccatttta tttgcaacga taatttgcgg 2718721 acgctcagtg agacgcagat tgtactcgct cagctcctgg ttaatcgtaa gataatcatc 2718781 atatggatca cggccttcta agcctgacat gtcaatgaca tgaacaataa ccctcgtccg 2718841 ttcaatatgg cgcaaaaact ggtggcccag tccgacgcct tggtgtgcgc cttcaatcag 2718901 ccctggcaaa tcagccatga caaagctgcg tccgtcatcc gtttcaacca tgccgagatt 2718961 cgggacaagc gttgtaaagt gatagtccgc aattttcggt tttgcagatg agacaacaga 2719021 cagcaaagta gattttccca cactcgggaa cccgacaagt ccgacatctg caagcacttt 2719081 taattcaaga acaatgtagc gttcttttcc cggctcgccg ttttctgaaa gctgaggcgc 2719141 gggattagcc ggtgtagcaa agcggctatt tcctcttccg cctcttccgc ctcttgcaat 2719201 gacagcccgc tgtccgtgct ctgttaaatc agcgatgacc tgttttgtat catcgtctgt 2719261 cacaacggtg cccggcggaa ctttaatgac catatcatca gcatttcgcc cgtgctggtt 2719321 tttggacatg ccatgctcgc cgcgaatcgc tttaaagtgt tttttgtatc taaaatccat 2719381 cagggtgcgg agaccttcat ctacttcaaa aacgacgtct cctccctttc ctccgtcacc 2719441 gccggcaggg ccgcctttcg gcacatattt ttcacggcga aacgcaacca taccgttgcc 2719501 gccgtcgccg ccttttacat atactttgac ctgatctaca aacataatgt cctccgttct 2719561 aaaccgttaa aaactccgct agtccaaccc aatttcaatc agacattcgt gactcgtgat 2719621 ttcaaaacgc atgatatcaa cgtcctcata tccattctgc cgaatatcat caaaagcaga 2719681 tggatcggca aaggcgccgt gaaaatcaag gtacagaatc agctgtctgt caggatgatc 2719741 cgtttgaagc gaaaccgtta aatgattttc actctctctg ctgactgctt gatcaaacag 2719801 atgaaacagc tttctcatca gtttcgccag cttttgatca taagccgaca aatccttaat 2719861 ttctccgaga acttcatatt caagcgtcat ataatgggtt ttccaattaa acgtaagaaa 2719921 atcaaacgcc aaatgcggtg ttttcaggtt tgagagcttt gattcgtgct ttgcgtctat 2719981 aaccatttct tcaatcattt caaagacacg gtcatacttc tgtaagctta agtttccttt 2720041 aatcagctgc agcttattca tccaatcatg ccgggaatgg ccaagcagat gaatcagttc 2720101 gtttgttaat gccgtgtcgc ttatattttc ttcttgattt tttgaaacat ccttcatttt 2720161 cgcactccca atcatttaat ttcttattta ggagtctgta taagtgtgta ttatgaatta 2720221 taacagagaa ggctttgtta gaaaaacaat tgtttttccc agaaatatca tgttcctttt 2720281 ttctggcttt ggttgatttg cagccaggca gaacatttta tgtattactg cttggggaac 2720341 atatccagtg ggtttgagat gtttattctc attcttggcg gggtctgctc gcacatactc 2720401 tgcatttcat tctaggtgtt tactccgcat attgcaaaaa aaactccagt catcatcgac 2720461 cggagttttt tgaatcatta ttgagctaca ggatatacgc tcactttttt gcggtcacgg 2720521 ccgaaacgtt cgaatttaac agttccgtcg attttcgcaa atagagtgtc atctccgccg 2720581 cggcccacgt tttcacctgg gtaaattttt gttccgcgtt gacggtaaag gatagaaccg 2720641 cctgttacga attgaccgtc agcacgttta gcacctaaac gtttagcctc agagtcacgt 2720701 ccgttctttg tagaacctac tcctttttta gaagcgaaaa actgaagatc taatctaagc 2720761 atgtagctca cctcctatat tatgtttgtg gtcacacgca agttgtcttt gtaatcccgt 2720821 tcgattgtct ccagcgaaac aatcatgcct tcaatcagca gctgagcttt ttggcgtgcc 2720881 tctggatcaa gagattcagg gaattcaaaa taaaaataac ccccgtcctc tcctatatca 2720941 agaagcggct cgaagcccgc gagcacaatg accgcgttaa cggccccaaa cacaacggct 2721001 gtcactccgg cacaaacaag atcttgtcca tgttcagcaa aattcgcatg gcccgtcatt 2721061 tcaaaagaca atatgccttt atcatgagac cttctgattg ttgcctgaat catgcttacg 2721121 cgttgatttt ttcgatcgtc actttagtgt aaggctgacg atgaccttgt tttttatgaa 2721181 cgtttttctt tggtttgtat ctgaaaacag tgattttttt cgcgcggcct tgtttttcaa 2721241 ctttagccgt tactgttgcg ccttcaactg tagggttgcc gactttcacg ttgtctccgc 2721301 caacaaacaa aacgtcttca aaagtaactg tttcacctgc ttcagcagca agtttttcga 2721361 tgtaaacagt ttggccttct tcaactttga tttgtttacc gcctgtttta atgattgcgt 2721421 acattctctg cacctcctat tagactaaga ctcgccagat accagggggc tgtaaaagct 2721481 cttaacacct gtactgagcg gttgtagcaa tggtgctaca tccataacat taaaaaatat 2721541 accaaaatac aaggcgtttg tcaatcagtt ttagtagggc agaagcagtt cctccatgga 2721601 agaattcgtc cgcttatcgg caaagtaagc gtgcagcact tcattctcgt caagctggct 2721661 gagcttttgg cctgattttt ctataataat cggatgctta cagccacgtt tgaactcggc 2721721 catcacatga tagactttat cctccgcctt tactgtcagc ggcagaagtt tctcaagctc 2721781 cctgtttttt ccgtaatacc tttcgaggag aaatctcaca tggatatagt gcctttgccg 2721841 atattcctca aacaaggaaa cagccagaaa gacaaacaaa acccatgcgc tgatttgcag 2721901 aggaatcacg aataaaaccc agcacccgag cagcaggcag aagcagagcg acgtttttag 2721961 attaagccgg tgagcctttt gaaaaggcag ctgtttggaa aacaacaaaa ataacagttt 2722021 tcctccatcc agcggccaga tcggcagtaa attgacaaat aagatagaaa gattataaaa 2722081 ggtgaagagt tcaaaggtat gctgatgaat cactgagact tctgcaagca tccaggcggc 2722141 aaactgaagc cagatgtgct gaagaggtcc ggcaataatg accgcaaact cttcctttaa 2722201 cggccgattc ccgtgctctt ccacttcgac cgttccgcca aacggcagca aaaaaacacg 2722261 cttgattctc caagaaaaaa acacagccag agcagcatgc cccagctcat gaatcaatac 2722321 aatcaggagc agacataata atgctttcat atggcctgtg agcaagccca gcgccgcaat 2722381 aatccaaaga aaaggatgca catggatctt taagataagg tcgagccatt tattcaaatg 2722441 aaatcacctg aatcggatca ataaatttat cgccgtcttt catggcaaaa taatagaccc 2722501 ctttattatg atcatcaagc ttaatcgaac cgagcttttt gcctttatcc acaaaatcat 2722561 ataaagcaac atccacatct ttgagctcgc catagatact ataggtgttg tcagcatgct 2722621 gcaccttaac cgtcagtccc gtttggctgt ctttgctgac ttcaaccaca tagccttctt 2722681 ttacgctatc aatcttatca ctgcttgttt cgactttaat tccttcccca ttgtcctgaa 2722741 aatcctgctg tactttcccg gatgcaggcg cgatcagatc tttgcctact tcaatctgct 2722801 gttccttatt tttgtgttca ggagccagga aagcaagcgg atttccgaat ttggtttcga 2722861 accaatggct tgctgaagca aattgaaatt cagtttcaaa ggttttggct acggcgggtt 2722921 taatctgact gacgggtcca atgtttgttt tataggctat agctgaaacg agaacaaggc 2722981 aggccgacag aagacatttc aggataattg aatctgtttt caccaatggg tgttttccgt 2723041 tgaatgttgg catgttatct tcgtagaccg gaagtgttcc atgcttttcc tgatccgtta 2723101 ccatcaccca ggacgggggt ttctgctttt cagaaactgt ctgagtagag aaacgttttg 2723161 agccggaaag ctgctttctt cttttctcta atcgttttct gatttcatct gctctgtgac 2723221 tcattgccat catcctttgc attcgttggg tttgtacatc atatgtcttg tccatggcaa 2723281 atattcggtt tagtcaagaa caaagcaggc aaaaacaaaa aaaacctgac acagcatatg 2723341 ctttgtcaga ttcttctctt tgattctatc acattaagat cttactccga aaaatgactt 2723401 aatcttagcc atcattcctt tgttttgctc ttcaagcacc tgtaaaggaa cagattcacc 2723461 taagatgcgg cgggcaatat tgcgatatgc aatggaagcg cggtttttag ggtccatcgc 2723521 aatcggttcg ccatgattgg aagctttaat gacttcatca tcatcagcca cgattccgag 2723581 caaatcgatc gacagatgct gtacgatttc gtcgatatcc atcgtgtcac cgtttttcat 2723641 caggtgattt ctgattctgt taacaacgag ccgcggcggt tcaatatttt cctcttgctc 2723701 cagcagtcct ataatacggt cagcatcacg aacagctgag atttcaggcg tagtgaccac 2723761 aatcgcttta tcagctccgg aaacggcatt tttgtaccct tgctcgattc cggcaggaca 2723821 gtctatgatg acatagtcaa attcctgttt gagctcttgg accatgtttt taatttgttc 2723881 aggagcaaca gctgtcttat cgctcgtttg agcagcgggc attaaataga gcagatcatc 2723941 gaaacgtttg tcttttacga gcgcctgatg cattttgcat ctgccctcta caacgtctac 2724001 cagatcgtaa ataattctat tttcaagacc cattacaaca tcaaggttgc gcagtcctat 2724061 atcagtatct actaagcata cgcgcttccc taaaatggct aaggcggtac cgaggttcgc 2724121 agatgttgtt gtcttaccta ctccgccttt tcccgaagtt attacgatag cctcacccaa 2724181 ttcacattcc tccctcaagc cttgttagat caggtcttaa atgagccaaa tgttgaaggc 2724241 gttcaatgac catatttccg tctgtatcta aataagcaca ttccatttcg ttcccttttt 2724301 gaatgtggtc tggggagcga tttaacacat gattgattct taattgtgtc ggaagcattt 2724361 cagaggcggc gatgaccgct tgattatttc cattgaatcc agcatgcgca attcctttca 2724421 gtgagcccag aacaaaaatg ttccctccgg ccctgactgt tccgccggga ttcacgtcac 2724481 cgatcaggag caagtcgcct tttacctgca gcacttggcc tgaacggaca atttttgaaa 2724541 cagaaataat ttcggcttcc tctcttatct gctgtgcttc ttttttagta atgacttcac 2724601 tgtcaataga atgaacaaac aaatctttct ttgacgcaat caattcggtt agctgttcct 2724661 cttgctcctt atataaaaag cgatttccca gcttaacatg aacgctgatt ttctggcctt 2724721 ttccatcggt atattgttca attgacagca tattctgaag accatcgaga agctcatcaa 2724781 aagaacacgc atcatccaga tgcaatgtta gtccattctt tgttcctttt attgttacat 2724841 attgctgctt tttggtcttc acaatattca cctcaacaac atactcattt cgtcaaaaaa 2724901 agataaaatc ctttttactc atctctcaat tctttcttta gactcataaa aaacaatcta 2724961 aatggcagaa caagaataag agctgctgca atatttaata aaattgtcgg tataaaccgg 2725021 tcaagcacaa atccgttaaa cgtcataatg tctttatgaa tcaaagactg aatgccgaat 2725081 acgtaaaatt cgagcagaca gacagccaga actgctatca atatcactac aaatgcgttt 2725141 gtatgcaaca ctttaaacgc ttttgaagcc aaatagcata gccctgcaaa accaaacatg 2725201 taaacgccta atagacttgt atagttcatg tcatatagaa agccaaaaat aaatccgtaa 2725261 atcatcgcgt gtttttggtt gataaaagcc gacatgaata tcaatacaag catcaaaaaa 2725321 cgcggggcga gcacttggtc atctgtaacg aaaggaaaat gcaccaaatc tgtaaaaatg 2725381 ctttccgcag aaaaaacaag catcataacg aaagggagaa ggaaacgttt cacgatcctt 2725441 cctcctctgt atcgacagtc ggcacgtcac ggttaacaac gatcacatta tttaaatctg 2725501 taaggtcagc cgcaggtttt acataagcaa ccttcgttaa tccataggaa tctgactcga 2725561 tatcagtcac ttcaccgatt gtcagccctt ctgggaaaac accgcctgtc cctgatgttt 2725621 caataagatc gccttttttc acgtcttgtt tatccttacg ctcaataatt gtcatcttaa 2725681 gacgtttttt ctctttgtca tatccttcga tcaagccgta gcctttgctg cctttttttc 2725741 cggaaatttt tgtcgcgact ctgttattgc ggtcagtatc gcttaaaagc tgaacagcag 2725801 acgtaaaatt gttaagtccg gagcttttga tcttgccgat taatgcgcct ttttcgtttg 2725861 taacggccat atctttcgct acgttttgct gagtcccctt gttaatggtg acctgtttcg 2725921 cccaattatc agggcttctg gcgatgaccg ttgctaaaat cggcttgtaa tctttaatcg 2725981 atttgacatg gccaagctcg tcacgcaagg atttgttttc ttcttcaagc tcttgaagct 2726041 tggcttcata ttgtgtctgt ccgtcaagtt tttctcttag acgctcgttt tctttgtatg 2726101 tgttttttaa atcattgatg ttctcaaata ttcctgcaaa aaattcggca ggcgtatgaa 2726161 aaatattttg aaatactccc gtcgtatcgc cgatcacttt ctcaggccag gtggtattgc 2726221 ggccgccctt cagcgaaaat ccaatcatag ccaccaatat gataatacac agaagtaata 2726281 gcattaaccg cttattcggc atcgtgttac acctcttcta ttgaactccc gattatctag 2726341 ttttcccttt gaaaagatgg atgtgctcca gtgctttccc tgttccgatc gctacacaat 2726401 caagcggatc ttcggcgata aggaccggca tttttgtttc ttcgctgatg actttgtcca 2726461 aattgcgcaa aagcgctccg ccgccggtta acactatacc tctgtccatg atatctgctg 2726521 caagctcagg cggtgttttt tcgagtgtgc tcttcactgc ttcgacaatt gtagatacag 2726581 tgtcgcgtag agcgttagaa atctcttttc ctgtaatttc aattgttttc ggcaaacctg 2726641 tgagcaaatc gcggccgcgg atttccatgt tgtcggattc ttcaggagct tctgcagatc 2726701 cgatttccat tttaatcgct tcagccgtac ggtcaccgat catcagattg tacgtttttc 2726761 tgatgtagtt gataatcgcg tcatccatct catcaccggc tacacggatt gactgagacg 2726821 ttacgatgcc tccgagggaa ataatcgcaa cttctgtcgt accgcccccg atatcaacaa 2726881 ccatgcttcc agtcggttcc caaactggca gattggctcc gattgctgcg gcaaaaggct 2726941 cttcaatcgg atacgcgtca cgcgctcccg cctgtcttgt cgcatcgata acagcgcgtt 2727001 cttcaacagc tgtaatgcct gatgggacac ataccattac atatggtttt ctggcaaaca 2727061 tgcctttatt ttttatggcc tgattgatgt aatatttcat catcgtcgcc gttgtttcat 2727121 aatcagcgat aacgccgtct ttcatcgggc gaagagccac cacgttgccc ggtgtccgtc 2727181 caatcatatt tttcgcatca tttccgacag cgacaatcga tttcgtatcc gtctgcaaag 2727241 cgacaactga cggctctctc acaacaattc cttttccttt tacaaaaaca agcgtattcg 2727301 cagttccaag atctatacca aggtctctag caccaattcc aaacatatgt atgtatcttc 2727361 ctttcttaaa gcaaaaatac cctaaaggga aaaactcata aactctatta tagcttaatt 2727421 cgacgaaaaa aaaagtgtta caaatatcct ttttccttta aactcacaaa ttttttatcc 2727481 ccgatcacca aatggtcaag cagctcgatg ccaatcaggt ttccgcattc aaacagccgt 2727541 cttgtcactt caatatcttc cctgctcggc gtcggatctc cagaaggatg attatgaaca 2727601 cagataaagg aagcggcaga tcgtttaaac gcttctttaa acacctctcg cgggtggaca 2727661 atagatgaat tcaggcttcc gataaatacg gtgcgtttat ggatgacttg attttttgta 2727721 tttaagtata aacagacaaa atgctcctgg gttaaaaagc gcatatcctc catgacaaga 2727781 ttagcgccgt cttccgggga gcgaataacg aaatgttctt cgttggctaa tttatgaatc 2727841 cggcttccaa gctcaactgc tgccagtatt tgaatcgctt ttaccatacc gattcccggg 2727901 atgcttgaca gctcttcaac cgatgcttcc ttgagcaggc gcagcccgtc aaatgagcgc 2727961 agcagccggt ttgacaggtc caaaacagat tcgtgtttag tccctgtccg caataatata 2728021 gccaaaagtt catgattcgc taagttctcg gctccgactt tcaggagccg ttcccttggc 2728081 ttttctttca ttgggaaatc tttgagtttt aatggcagat cgtgtatgac caagcactcc 2728141 ttttctttcc cttcccgttt atagaaccgt catgccctta tatcaaaatg gcgaagagct 2728201 ctcattgttt ttgatatagg aaggcccatg actgaataat aatctccgtc tattttcttt 2728261 acaaaaagcg cgcctcttcc ttggatgccg tatgcacctg ctttatccat cggctctttt 2728321 gtttcaatat atgtccaaat ctcttcttca ctgagggacc aaaacgcaac ttctgtctta 2728381 tcataaaaag tctcgctgtg attttcagct tgaatgctga ccgcggttat tactgagtga 2728441 cttcggcctg aaagcctccg cagcatagaa gcagcttctt cttgatcctg cggtttgcca 2728501 agacattcgc cgtcaaggca taccattgta tcagcaccga taacgattgc atgcgggtgg 2728561 agatcagcta cagccttagc tttttgtttt gccaaccatt ggacgttttc ttctggtgaa 2728621 aagtttcgat ttaatttttc ttctacttca ctgacaataa tggagtaggg cagctggaga 2728681 agatcgagga gttctttcct gcgcggagat tgtgatgcaa gtattagcgg ttttgtcatg 2728741 ttcgtcatcc tttcagggtt tgcttaagaa aaaaagatac tcgtttatcc taccaaatca 2728801 cgaggcttgt cacaatttca gaaaaataac tttttcatga caaaataaaa aaagcctgtc 2728861 actaaaggac gaaggctcag ggcactatct cttattttac gacggctaac agctcctgct 2728921 gagccttcca cccggcttca gcacttggat cctctaattc ctttaaagcc tgcaaaatcg 2728981 cttttttctc tcctgtttct gacgcttttg tttcaccaag cgacttttct attttctcta 2729041 cactcgcttt tgtaatgtct tcgtcgagaa tcgcctttgc tgcaagctcc gctgtttcct 2729101 taaaagaatc tgtcatatct gactctattg ataaggaaag ctccttgcct ccccaggctt 2729161 caaaatcact gtcgattaaa acctgtccta actgctgtga gacctccttt tcacttgcta 2729221 agcctgcaat aacatacgta tacccgtcat cctttgacag tgacacggcg gaatatcctt 2729281 tttcggtcaa ttgttctgtt aacgtttcgg cgcccttttc atttgaaaat tttccggctt 2729341 gcacagcgta tgttttgtat gtaccttcag tttgtgccgc ttgtttttct gcgcctgagg 2729401 tttgtttatc agcagaagta tcccctgctt ttgccgtttg gctgcctaaa gaatcctcta 2729461 aagaggccgg tgctgacgct tctttattcc ccgatatgtt taacgcgaat aaccctaatc 2729521 cagtgccaat gacagccgcg aaggcaatcg tcgcggccac tctttttacc ggtttggcag 2729581 ccccggtctt tccttttgcg taaagctttg tttttttctt ttgaaaagga ggaacaactt 2729641 tagggtcctc tttaaacacc ttgtcctcct cggaatccca attgaattca tcttcatcag 2729701 ggtgttcctg ggatgccgca acctcttgtt ctgcctgtct tttttcctcc caatttgaaa 2729761 atgtcatgct tttattcgcc tctgtctcag gcgtctcttg ttcgtaaacc gtctcttctt 2729821 ttccattaat cgtcaccttg agggcttttt ctgcggcttt actgtttttt ttattctttc 2729881 tttttttcaa ttccgcttcc tcccttcatt tgcttgaccg ttcttgtcgg cttttcatgc 2729941 tacacacttt agcacaggca aagaaaaaaa gaacaagact tttgtcgcct tgtccaaaaa 2730001 acgttcgtca aatttttcag cagtcagccc aatgccattt tgatataaaa agaaatgata 2730061 gagtcaccgt ataaataggc taaaatgctc cctgcggcta tagcgggggc gaagggaagc 2730121 ggctgccttt tagcgagtct accagtcaga acagctgccg ctccatataa tgcacctatc 2730181 aaaactgaaa agaaaaaggc agctgccagc attttcacac caagcacaaa gccaatcacc 2730241 gcaaataatt taatatctcc tccccctact cccccatggg tgattgcggc aattacagcc 2730301 agaaacaaaa atccggctgc cgcacctaac aggcctgcat accaggaatc aagcggagaa 2730361 atcaatctcg cggccgccaa aaagggaaga aagaaaatca atattcgatt tggaatcagc 2730421 ataaaatgaa tatctgtcac tgcaacaata atgagaagag agataaacac cacagcggga 2730481 aacagttcca gcgatatgcc aaagcgtatt cctgcggcgg caaataaaca cgctgtcaca 2730541 agctctgctg cgggatacat aaaagaaatc ctatgcccgc agcttttaca tttacctttt 2730601 tgaaatagga atgacaggat gggaattaat tctgcaggag ttaatgttcg ccggcaaaac 2730661 gggcatgatg aacggggcgc aataatagat agatgtaagg ggatacggca cccggccgta 2730721 tagtaaaaag aaccaaggat aagcccgaag ataaaaagaa tggatagcat agacaacaca 2730781 cctttactca ttgagttctg gtatggattg tagcaaaatg gacatcctga gctccaattg 2730841 ggaatattca attttacaca tgaaaaaaac ggcagaatct ttttttgatt ctgccggagc 2730901 cggatgcttt tatttcaacc tttttcgaat gtcagaaata aagtaaagag atccggtaat 2730961 cagcacaatt tcatttgagc cctttttact ttctatgaat ttgattacat cgtctggatc 2731021 ttcactccag cttttattgc tgatttcact tgcatcatag agatcttttg caagggaagc 2731081 acgcgggaaa tcaaaagaag caaaatgaat cgcatgagca atggtttcca gtcttttaat 2731141 catgttctga tacggtttgt cctttaacgc gctaaacacc acagaaatgc gtgaattggc 2731201 gaaacgctgc ttcatcgttt ccgccagctt ttcaacacct tcttcgttat gcgcaccgtc 2731261 taaatatacc ggaggatgtt cctgaacaag ctctaaccgt cccggccaag cagccttcac 2731321 aagcccgctc cttaacgctt cgtcactgat atgggcgata ttctccttat tgagccactc 2731381 cgcagccaaa atggacaaag cagcattttg tctttgatgg gtgccaatca gagatgtccg 2731441 aatatcttca tagcatttct cttccgtttt gaatgaaaac tgttctcctg caggcagagc 2731501 ctcttcattg aaaataacac atgcatcatg caatgactgg aacggcgcag catgccgttc 2731561 ggcttcatgg cggatgacct gtaaagcttc cggctgggta actgctgtaa cgattggaat 2731621 accttcttta ataatgccgg ccttttctcc tgcaatttct tcaatggtgt ttcccaaaat 2731681 gttcatatga tcgtgtccga tgcttgtaat cacagttaag agcggttcaa ccacattagt 2731741 agaatcgaat ctaccgccca gacctgtttc aaaaataaca aaatcgacct tatgaaactc 2731801 tgcaaaatat aaaaatgcac aagctgtcat aatttcaaat tctgtcggct gtccgtattc 2731861 cgtttgatca agggcttcaa cgtgcggttt catttgattg acgagtgctg tccattcctc 2731921 atctgaaatc ggtatcccgt ttacgctgat ccgttcatta aacgtaataa tataaggcga 2731981 tgtaaatgtt ccaaccgtat atccggcttc ctgcagcata gaacggataa aagcgacagt 2732041 tgatccttta ccgtttgttc ctgcgacgtg gaacgctcgg attttttttt caggatgtcc 2732101 taaccgcgcc atcagctgtt tcattcgacc aagtccgggc ttcaccccga atttcagcct 2732161 cccgtgaatc cagctgcgcg catcttgata tgcagtaaac aatgataatc ccctctttta 2732221 taagacaagg cggtttctct agaaaccgcc ccggcttttc attaaccctt cagctcagcc 2732281 attcgttttt gaacagcgtc acgcttcgcc acataatctt tttctttttc acgttcttca 2732341 tcaattacgt gtgcaggcgc ttttttcata aatccttcat ttccaagttt cttttggaca 2732401 cgctcaactt cttttgtcag tttatcaaat tctttttgca gacgggcaat ttcttcatca 2732461 atattgatta agccttcaag cggaagaata acctctgctc ctgagacaac ggccgtcatc 2732521 gccttatcaa cagcctcaat atcggtgccg attttaagca cgctcggatt cgtaaagcgt 2732581 tcaacatatg aacggttcgc ttcgaggcgg gacgctattt cgtctgtgct tgttttaatg 2732641 tacagttcaa cctgcttgct cattggcgta ttgacttcac tgcggatatt gcgcacagaa 2732701 cggatcagct caacaagaag cttcatgtca gctgccgctt cagtatcggt atgctccggc 2732761 actactgcag gccattgact tactgtaatc gattcccctt ggtgaggaag gtgctgccaa 2732821 atttcctccg ttaagaatgg cataaacgga tggagcagac gcatcgtttg atcaagtacg 2732881 taagcaagga tggaacgggt agttttctta gccgcttcgt cttctccata aagcggaagc 2732941 ttcgccattt caatatacca atcacagaaa tcatcccaaa taaagttata taaatggcgt 2733001 cctacttcac caaattcata tcggtcagca agctgggtca cgtgctcgat cgtttcattt 2733061 aatcgcgtta aaatccactt gtcagcgact gacttttcac ctgacagatc aagctcatcg 2733121 tacgtcatgc catccatatt cattaatgca aaacgggagg cgttccaaat tttattggca 2733181 aaattccagg tcgattccac tttttcatag ctgaagcgca gatcctggcc aggagagctt 2733241 ccagtcgcaa ggaaataacg cagagaatcg gctccgtact tgtcaatcac atccatcggg 2733301 tcgacaccgt tgccaagaga tttactcatt ttccggcctt gctcgtcacg gattaagccg 2733361 tggattaaaa catctttgaa cgggcgctcg cctgtaaatt caatgccttg gaaaatcatg 2733421 cgtgataccc agaagaaaat gatatcgtac cctgtcacga gaacatctgt cggatagtag 2733481 cgtttaaagt cttcagccgt tacatcaggc cagcccattg tggagaaagg ccatagcgca 2733541 gaactgaacc atgtatccag tacgtctgta tcctgttccc aattttcgct gtcttccggc 2733601 gcttcaagtc cgacatatag ctcgcctgtt tctttatgat accaggcagg aatacgatgg 2733661 ccccaccaca attgacggga gatacaccag tcgcggatat tttccatcca gtgtaaatac 2733721 gttttttcga aacggtcagg cacaaagttg accttttctt cttttttttg cagctcaatc 2733781 gctgcatcag caagcggctg catgcgcaca aaccattgtg tagaaagata aggctccaca 2733841 acagccccgc ttcgttcact atggccgaca gagtgcatat gatcctcgat cttgaagaga 2733901 actcccgcct cctgtaaatc tttcacgagc tttttgcggc attcaaaacg atccatacct 2733961 tgatattgga gcgcattttc attcatcgtg ccatcttcat tcatgacaag gatgcgttct 2734021 aaattgtggc ggttgccaag ctcgaagtcg ttcggatcat gagcaggcgt aattttcacg 2734081 gcacctgaac caaattccat atcaacatag tcatcaccga caatcggaat ttcacgattt 2734141 acaatcggca ggatcaccgt ttttccgata aggtgtttat agcgctcgtc ttcagggtga 2734201 acggcaacag ctgtatcacc gagcattgtt tcaggacgtg tcgtcgcaat ttcaattgag 2734261 cctgaaccgt cagcaagcgg atagctcata tgatagaatg cgccttgaac atccttgtaa 2734321 atcacctcaa tgtcggatag ggctgttttt gtcgctgggt cccagttaat aatatattcg 2734381 cctctgtaga tcaggccttt ttcataaagc ttaacgaata cttcccttac cgctttgctc 2734441 aagccttcat ccagcgtaaa acgttcacgg gaataatcta ggccaagacc taatttcgcc 2734501 cactggctgc gaataaagtc agcatattct tccttccact tccacgtttc ttcgaggaat 2734561 ttttcacggc ctaaatcgta gcgggatttg ccttcttcac gaagtttcgc ctccacttta 2734621 gcctgtgtcg cgatgccggc gtggtccatg ccaggaagcc acagcacatc atagccctgc 2734681 atgcgtttca ttcttgttac aatgtcttgc agcgttgtgt cccatgcgtg gccaaggtga 2734741 agtctccctg ttacgtttgg cggcgggatg acaacagagt atggctcttt tgtctggtca 2734801 ctgcccgctt caaaaaattt gccttttagc caaaaatcat atcggtcttt ttcaaccgct 2734861 gccggatcat atttcgtcgg cattgtttgt tcattcgttt ccatcataac cctccagcat 2734921 gtttaaaaat ggctgagaac gaaaaaagag ctcttcatcc ctgtaaaagg acgaaaagct 2734981 ctttcgcggt accacctttt ttcatgaact caatcagttc atgcacttat aacggataac 2735041 gggtgtttcc cgaatttctc tactcttctt tcaagaaatt atgctcccgg gcgaccttcc 2735101 aatcagacaa cataagaagc ctttcagcaa acggcttctc tctctgcatg cgcctttttt 2735161 gtactcttcc cgttctaagc aggtgtattt atcagctcat tgtatacatt atttatgttc 2735221 tttattatag taaaagtgtt tttgattcgt caatcatctt ttccaaaaac accgctttct 2735281 atacagatgg gcaggcacct attgcccaag tttacatatg atgcttgtaa atgcgtagag 2735341 gaggatgcac cgtgaagaaa cgtttcagct cttattcgct gccgccatgg gtaaggcaaa 2735401 ttcggcttgt atccgcacaa gtgattattc ccattacgat ttttcaagga atcagaacca 2735461 ttttctttcc gacaaccttt gatgttttgc tgctcgcaat cctaatcttt ttagcttgcg 2735521 cccttcattt agaatggata taaacaaaca agtccgcgcc attaagacgt ggactcgttt 2735581 tcagcctgaa attttttctc ttgttcaatc tgatgaattt tcatcacaaa cggctctatg 2735641 tttttcattt gccaataagc ctttaataat tgtgtacatt cctctttttc atgctgtctt 2735701 ttcccagttt gataaccgtt cagcaccttg tacatggctg ccggatatgc catatagctg 2735761 agaaaaaggc tgacttccgc ttcacgcaaa gggaatgatt tcgtatatcc ataaaaccat 2735821 tcgacgcatt ccggacaagc tttcggaaag cctctgaaca tttttgtata aaagccgagc 2735881 aggtcgtttt gcggcggacc gacagatgct ctttcgaagt ttgtaaaata tccggtcccg 2735941 gcatcattat acagaaaatg gtgtatagac aggctgccgt ggttcattac aacccttgaa 2736001 acgtcctttt cctttgcgga ctcataccag tcctccagcc gttccagcgc aaagttcacc 2736061 gcggaaatgg tttcagaaaa ataggttatg gcctggagtt caaagggaga aaggtaccat 2736121 tccttctccg ctctatccac aaactgctca tagaaaattt tatcttgttc ccactttttt 2736181 ttcgtttgcc cgtaataacg ttcaatctca tcacgtctaa cctttagttc ctgcgcggtt 2736241 ctctcgtgaa gacgggctgt ttctctaaat aaataagcat gtttttgatc ccgttcttcc 2736301 tcttggtcaa attggagcca aggcattaaa tagtagatat ctccgtattg tatgcctgct 2736361 gagaaaaact caccgctatt tgttctgtaa acgggaacga atgaacgaaa gcctttttcc 2736421 tcaatcgcca ccatatgatc tgtaaaatgc ttgccgcgac cttctttcaa ttttttcagg 2736481 gcaaatatgc cgtagtctgt atacactttc caaacaagag gactgacagg ctcaataaat 2736541 tgagcagtca gtccgtattc ctgaagaacc gattgggtat cttccatttc attcaccaca 2736601 ttttccgatc acttacggtt tacgcatggc tatttttata ttgaggaata tagagaatct 2736661 gtcctgcttt taattcatca tccaaggcta aagaattcat cctgatcagc tgctgggatg 2736721 taatttcata ccgttcgcat aaacgctcga tcgtatcttc ctgctgcaca atacaaattt 2736781 tcattctcga aaactcatcc gcttcttttg taaagagttt tgttaaataa agagaattat 2736841 cactttcctt tgtttgaggt tccttcgttt cagcagcagg agcaacccta ggaacagcat 2736901 ccgtttcctt cctttcagtc tcagaagatt caggcagctg gaaggattga aaaggtgttt 2736961 cttccttagg ctcttcagct gatggtgttt ttctcacttc aatttcgaag ctctcttcct 2737021 cttgttcttc ctcctccagc agcttaggcg ctgaataaaa agaatcctcc tcttcttgtt 2737081 caggcaggaa ggtacggtat gccggttcag gcaattcttc ttgagatgcc tcctccgagc 2737141 ttgttttttg attgaaatgg aaatgtaaat cggcattgtc attctccata tatacagctg 2737201 aagctgtttc tctgctatct tctatggaga gagcggcctc tgatacactc tccaaagctt 2737261 catccggttc cgcctcttct tggcaaagcg caggatcagc ctgatccgat tgagctgctt 2737321 cttcattttg agcctcttgg cgcagcgcat attcatgatt aggagacact gttgtttcct 2737381 ctttttcctt tgcaatcaca gtctctgaat gaagctcagc ttccaaagca ggcgattctt 2737441 ctgctccaac gtgttcacga agctcagtct ccgctggaga gtctgcttct tcacgaacat 2737501 ccgctattgc agctgccggc tctgccgttt ctttttttgc tttaacgatc tcttgaatct 2737561 ctatttctga aggatcaggt tctggctcag attcttctgt ttccgattca gcacgaacct 2737621 ccgtttccgg cacagcaagc tcttctgact cttcttcctc tttcacatct tctctggcct 2737681 ctggttctga agcaaccgat tcaggcggct cagattctgc tttttctgtc tccagttctt 2737741 cacggagccc cgctttcgag ataaaaagtt ctggcggttc ggctggcggt tcatgctgaa 2737801 gaactgcttc ctctgccgat gatgcacccg gttcttctac tacactatgt gccggcggct 2737861 ctgaaagctc ttcctccctg aatgccgcag gagcttcata taaaggtatc tccggctctt 2737921 tgtcttgcgt atcgtccaaa agcccttcga tcgctaaatc agcttgaatt gttaaaatgc 2737981 gcgaatccgt caattgatag tcaaatgcgt caataaagac gaagacatcc tgtaaatggc 2738041 tcactttatt tttcggaatg gtaatatcca caggaaaaca gtgagtcagt tccgcacttc 2738101 catcctctct ctttctgact tgttcaacaa accgcttatc tgtataaatc tcttcggtat 2738161 gtttgttttg atctatgttg tactcacctg taagttcaag cgatcctatg attgatacat 2738221 aatcatttac ttcctgaacc ctaatatcag gatctaatga aatagaaagc agttcagaaa 2738281 cttcctgtcc tttttggaaa cagatcgatt cttctacaga aaattgcaat cgatgatttt 2738341 gcggcaagtt catatcctcc tttcatctaa tccttaaaat tagatgtcac taaaggtgta 2738401 tgtatgaact ggagaaaata tgagtgggag agcacgaaaa aaccggcaca aggagtcctt 2738461 gataccggtt ttcactctta tctgcggctg atctcagcaa atactttctc agctgcctgg 2738521 attgtgtttt caatatcttc atcagtatgg gccgttgaga ggaaaagacc ttcgaattgt 2738581 gatggcggaa ggaatacccc ttcatttgcc atccctttat aatagcttgc gaacagcttc 2738641 aaatcagatg atttcgctgt ttcataattg atgactggtt cgtttgtaaa gaagaaaccg 2738701 atcatcgaac ctgcacggtt aaaggtatgc ggaatgccat gagccccggc ggtttttgaa 2738761 attccttctt ccagtctgtc gccttttttg atgaaattct tgtaggattc aggtgtcagc 2738821 tgtttcaatg tctctaagcc agccgtcatc gcaagcgggt tgcctgacaa tgtaccagct 2738881 tgatagatcg gaccgcttgg agcgatctgc tccatgattt ctgcctttcc gccataagcg 2738941 ccgacaggaa gtccgccccc gattactttt cctaaacaag tcagatcagg cgttacgccg 2739001 aagtagcctt gagcgcagtt ataatcgacc cggaagccag tcatcacttc atcaaaaatc 2739061 agcagggagc cgtactgctc agtgatatca cgcagaccct gaaggaaacc ttcttgcggc 2739121 ggaacaacac ccatatttcc ggcaactggc tctacaatga ctcccgcaat gtcttcaccg 2739181 aattgctgga aagcaagctt tacactttct aaatcattgt acggaacggt gatggtgttt 2739241 ttcgcaatgc cttcaggcac ccccgggctg tcaggcagac cgagagtggc aacacctgaa 2739301 ccagctttaa tcaagagaga atcgccgtgt ccgtggtagc agccctcaaa ttttaaaatc 2739361 ttgttgcggc ccgtatagcc ccttgccaaa cggagggcac tcattgtagc ctctgttccg 2739421 gagcttacca ttcgtacaat ttctacagat ggcacacgat caatgacgag cttagccagt 2739481 tcattttcta cttcagtcgg agcaccaaag cttgtcccgt attcagccac ttttttgagg 2739541 ctttctacga cgcggtcatt tgtatgccct aaaattaaag gcccccatga caagacgtag 2739601 tcaatatatt cattcccgtc aatatcaaag attttcgagc cttttccgcg ctccataaaa 2739661 atcgggtcca tgtctaccga tttaaatgcg cgaacgggac tgttcacacc gcccggcatg 2739721 agtttttgcg cttctttaaa agccgttttt gatttttcat agcttctcat ctgcctcaac 2739781 tcctgtcaac tgaataaaat tactccgcaa gccatttcgc tgcgtctttc gcatgatacg 2739841 taataatcag gtcggcaccc gcgcgcttca tgcttgtcaa aatttccaac acaatttctt 2739901 tttctttgat ccagccgttc tgcgctgcag ccttcaccat tgaatactct ccgcttacat 2739961 tataagcgac gagcggcaaa gtaaactcat tttttacgtc acgcatgata tccatataag 2740021 aaagcgaagg tttgacaatc aaaaagtccg cgccttcctc aacatctgat tgtgcttcgc 2740081 ggagtgcctc catacggttg gcagggtcca tctgatatgt tttgcggtct ccgaattgcg 2740141 gtgtgctgtt tgctgcatca cggaacggac cgtaaaactc acttgaatat ttaacagcgt 2740201 aagacatgat gggaatattg acgaatcctt ctttatcaag tgcttctctg atcactgtaa 2740261 caaatccgtc catcatgttt gatggcgcaa tgatatccgc acctgctttc gcttggctga 2740321 cagctgtctg cgccaaaagc tccagcgatt catcattgag aatgactccg tctttgacaa 2740381 gtccgcaatg gccgtggtct gtatattcgc acaggcacgt gtcagcgaca acaaccattt 2740441 cagggaagtg ttctttaatt tctgtgatgg ctttttggac aattccgtga tcatggtacg 2740501 cttgtgttcc gcaatcatct ttttcttccg ggatgccgaa cacgataaca gattgaatgc 2740561 ccagtttgac cagctccgct acttcatcct tcaataaatc taatgataca tggtgaacat 2740621 caggcattga cggaacagct tttttgcctt ccagcccttc aacgacaaaa atcggatata 2740681 taaaatctga tggatgcaaa cgtgtttcct ttaccatttc tctcattgct tttgatgtcc 2740741 gcaggcggcg gtgtctatta aatgattgac tcatattctc tcttcctctc ttgacatgct 2740801 gcacattaac tcaagcatgc catctattgt aaatgtatca ggcgtatgcg atgtgatgcc 2740861 gtacgtcaga agggcatcat ttgttaaagg cccaatgctg atacaggccg tcccattcgc 2740921 cttccacttt tttaattctt ctcccaagac atgcataaac gtatgtacgg ttgatgaact 2740981 cgtaaatgtt acatagtcaa aggaatattg acccgcagcg tctttcaatg cctcaatgcc 2741041 ttcttcatcc ggaatcgttt cgtagagaac ccattccttt acttcaaaac cgagcgggac 2741101 aagctcttgt tttatcacat cacgtgacaa attccctttc atcacggtaa tggtctcccc 2741161 cggttcagca tgctgcttaa gagcgtcagc caattgttca gcaatatact cctgtggcat 2741221 cacatcaacc gatacgttat gcatttttaa acggcgcgcg gttttttcac cgacggctgc 2741281 aattttttta tgcgcaggga gaataagctg attttccttc agataagaaa aaaagaagtc 2741341 tgccccgttc acacttgtaa aaacaagcca gcctggcgcg gcaagatcct ctcttacctg 2741401 ttccgcaaca tcattcggca aagcgcggcg aaacgtaatc aaagaggtta aaaccgcttt 2741461 accgccaagc gcctccactt tttgctgaaa tgatgctgcc tgtgccttat tccgggtgac 2741521 aagcactgtt tttcctttca acggaaaatc attttccatc ctcgtcaagc tcccgtttta 2741581 cacgatcaat taaatctttt gctcctttgt cagccataag agcggcacag cgctttccta 2741641 cttcctccgg atcgtttccg gtgacggttt ctttaaaaat gattttgccg tcaggtgaag 2741701 cgacaagacc tgtcatttca atttcatcct gtccatttaa cacggagtag cccgcgatcg 2741761 gaacctggca gccgccctcc atcgcgttta aaaaagcacg ttccgctaag acagtccgtt 2741821 ttgtatattc atctgtaaac tgagaaaaca acgccaacag ctcttcatcc gattctcggc 2741881 actcaatcgc cagggctccc tgccccacag caggcaaaca gcgctcaggc tcaaggaatt 2741941 cggttacgac atcttgcttc caacccattc tggaaaggcc ggcagccgct aaaataattg 2742001 cgtcataatc ctctgtttcc agcttttgaa gtcttgtatc tatattacct ctaatccatt 2742061 taattgtaag gtcagggcgc tcaatcaaaa gctgcgcgct tcttcttaaa ctgcttgtgc 2742121 caatgacagc acctttcttc atttctgaaa gctttacgcg attctttgaa ataagggcat 2742181 cacgcgggtc ctcccgttca ggaatacagc cgatcacaag gccttcaggc aaaacagcag 2742241 gcatgtcctt catgctgtgc actgccatat caatctcttc gtttaaaagc gcctgttcaa 2742301 tttctttgac aaaaagccct tttccaccca cttttgagag tgtaacatcg acaatccggt 2742361 cgccctttgt cacgatctct ttaatttcaa aagcaaacga aggattgatt tccttcagtt 2742421 tttgaataac ccattttgtt tgagtcatag cgagtttgct ccgtctggaa cctactttaa 2742481 tcgttctcat catttctttc ctcccgaatc tgcttgggac atcgtttaac tgaaccaatg 2742541 gaattgcgac aggcttccaa gcaggaaata attgatcatc agcaccagaa aacaagccgt 2742601 attccacagt gcagcgacct ttccttgcag ctccttaatc agcctgatat aaagataata 2742661 gctgtacagc agcaggacga caaacgaacc aagcactttg gcgtcaaacc aatacagcgt 2742721 ttctagtgag acatacgccc aaatgacgcc gagaatcaaa ctcagcagca gcatcggaac 2742781 cccaatgaca tttaaaacat acgccatata atcaagctta gataaatctt ctattctcaa 2742841 cagccatttt ccccactttt tctttttcag cagatgatat tgaaacatat atagcacaga 2742901 aaaaacgaaa gaaagggaaa aagcgccgta tgaaagaatc gccattgtaa tatgaatcac 2742961 caaaagctcg gatacaagct gcccggaaaa agcagctgac tgctgctctg tcggtgaaaa 2743021 tgtgtgaatg gcgatcatag aaaatcctat aacatttgta aaaaacacga taaagtcaac 2743081 acgtaaaagc tttgtcagta caagtgacag cgtgacaagc acccaggcat aaaaataaag 2743141 tgcctctgtc acatttaata ccggaaaccg ccccgtcacc cacataaaat aggccaaata 2743201 cacggtttgc agagtccaga caatagaaag caaccagaag gccatttttc cagccttccg 2743261 gttgtgttga agaaaatcta taaaataaaa gagtacactt aacgcgtaaa tgacgattgt 2743321 cccctcatta agtcttgcca ttgcagtatc aatcattcag ctttcactca cttacaagtg 2743381 ggctaaagcc cgcttttgat tcagccttct taaaagagtg gaccttctgg ctgctttcaa 2743441 cggttttcat catttgacgg cccgcagctt cttcaatatc aaaaatctgc ataaacaacg 2743501 cgagcttttc ttcagaatca gcatctgccg caagctcttt cacctttaaa atcggatcac 2743561 gaagcatttg gttaataata cttttggtgt gtttgttcaa cagttttttc tctcttgtgc 2743621 ttaagtgagg cagcttacgc tcaatgctgt ccatcgtttc tgactggatg gcaagcgcct 2743681 tttcgcgcaa tgcagaaata acaggcacaa caccaagtgt attcatccat tgtttaaatt 2743741 ccacaatggt ttcttcaatt aacagttcaa ctttttcagc tgtttctctc cgctctttca 2743801 tgttcgcttc tacaatgcct tccagatcgt cgatatcata aagaaaaaca ccttcaagat 2743861 cattcagcgc cggatcaaga tctctaggca cggcaatgtc gaccataaac agcggacgtc 2743921 ccttgcgaag cttattcgcg ttttccatca tctctttgga cacgacaaat tcacttgcac 2743981 cggttgaact gattaaaata tcagcctccg caagcgcgct ttcaagctga ttcaagcttc 2744041 tcgcttcacc tgaaaaacgg tctgcaagct ccttcgcttt caagtatgtt cggttaatga 2744101 cagtgacctt gccgattccc tgtccgtgca ggttttccgc agcaagctcg cccatttttc 2744161 ccgcaccgag aatcaatatg tgcttgcttg aaagatttcc gaagattttt ttggcaagtt 2744221 caactgcagc atagcttact gacaccgcat ttgagccaat gtctgtttcg gcgtgagtcc 2744281 gtttgcccac tgtaactgcc tgcttaaaca gctcattaaa aatagtcccg atcgtttttt 2744341 cttgctgagc tgttttaaag ctgtcgcgta cctgtccgag aatctgcgtt tcgccaatca 2744401 ccatagaatc aagtccgcag gctacacgga ataaatgctc aacagcggca tcgctctcat 2744461 aaaacgttaa gaacggtgac agctcttctt tgcttaattg aaaccaatca gctaaaaact 2744521 tttttatata ataacggccg gtatgaagct ggtcgactac cgcataaatt tcagtgcggt 2744581 tgcaggttga gacaatgatg ttttcaagaa tgcttttctc ttctttcagc tgcaccattg 2744641 cttctgccag ctcattcggc tgaaaactta ctttttcacg tatctcaata ggggcggatt 2744701 tataatctac tcccacaaca agtatatgca tcgctctaat tacaccccca acacccaatc 2744761 ttaatttata atcattctaa catagaactc attatttata ataattataa catagtttct 2744821 ttcacaaaat gtgaacagat tttaaaattc ttatgctata ttagaaaaag cttcagggaa 2744881 aagaagcatt cctattgaca ataccaaaaa cagcagaaat ttactacaca tcagctctaa 2744941 aaaacaagaa ggtgatatgc atgaaacaaa aatcaatttt attcccttgt ctgctgcttg 2745001 ccgcttctgt atatgcatgg ctagaaagcg gccaagccga actgttttca gggcaggatc 2745061 aatggcctgt tctcctcatg ctgttaggcg cagcctttgt atatcaagga aaaaaagaag 2745121 ccgtcacacc ccattttttt atcggtttgc ttctcttcgg gatcggttta cacttttttg 2745181 ccaagccgaa atgggtatgg tggccggatg attttgaaat gctcctcttt atgatcggct 2745241 tctcacttct cgtttcaacc gttcaaaaaa aagaatatgt atatgaagct gtgtcgatga 2745301 tttgtttttc cctgtttttg tactttttca aacaaattat ggcatggctt gagtctgcgc 2745361 atattccaac agcgcttctg aaggagtatt ggccgtttgt ctttattgga atcagtttat 2745421 tgttattatt gataaaacga aaaaaatcta tacgataaat aaaaccggta gaggatcctc 2745481 taccggttta tcattttttt gatcgctccc caagcttcgt cttttccctt tttcgtttct 2745541 gaagaaaaga ggatcagctc gtcttccgga tcaatattta atgtttgtcg gacaaccttc 2745601 gcgtgtttgt cccatttacc tttcgggatc ttatccgcct ttgtagcgat aacaataaca 2745661 ggaatgccgt aatactttaa aaattcatac atctgtacat catcattaga tggcgcatgc 2745721 cgcaaatcaa cgatctgcac cacagctttt aattcctcgc gtgtcgtgat ataggtttca 2745781 atcattctgc cccatgcttc acgctcagac tttgacactt tggcaaaacc gtagcccggc 2745841 acatccacaa aatgcagctc atcattgata atgtagaaat taagcgtttg tgtttttccc 2745901 ggctttgatg acgttctcgc aagatttttg cgattgatta atgaattgat aaaagacgat 2745961 tttcctacgt tcgatcttcc ggccaatgcg atttccggaa gccccccttc agggtactgt 2746021 tccggtttta ctgcactgat cacgatttct gactttgtga ctttcatttc ttctctccta 2746081 ctaaggcatg ttccaaaacc tcgtctaagt gggacgccaa tataaatgtc agcccctccc 2746141 tgacgctttc cggaatatcc tctatatctt tttcattatc tttaggcgca ataatggtcg 2746201 ttaatcccgc tctatgtgcg ccaagcgctt tttcctttaa gccgccgatc ggcagcacgc 2746261 gcccgcgaag cgtgatttcc ccagtcatgc cgacttcacg cgaaaccgcc cgtcccgtta 2746321 aagcagaaac aagcgctgtt gccatcgtaa taccggctga cggaccatct tttggcaccg 2746381 caccctctgg tacatgtata tgaatatcat acttctcatg aaagtcaggt tcaatgccaa 2746441 gttcttctgt tttggatcgc acatagctga atgcagcctg agcagactct ctcataacat 2746501 ctccgagctt tcctgtcagg attaatttcc cttttcccgg tgaaagcgat acttcaatcg 2746561 aaagcgtatc tccgccaacg gttgtatacg caagccctgt cactacacca acttgatcct 2746621 ctgtttcagc ttgtccatat ctgaaaatgc gttttccgat aaaatcttga aggttcttct 2746681 cagtaaccgt aattcgtttt cgctcttcag caacaatggc ttttgcagct ttacggcaaa 2746741 ttgcggcaag ctggcgttca aggcttctta cacccgcttc tctcgtatag taacgaataa 2746801 tatcaagaat cgcctgatca cgcagctgaa gattgctttt cttcagcccg tgttctttga 2746861 tttgctttgg aagcaagtga tcctttacaa tttcaagttt ttctatttct gtgtagcctg 2746921 cgatattaat aatttccatt ctgtctctga gcgggcccgg gattgtggcc aaattgttcg 2746981 ccgttgcgat aaacagcact ttggataaat caaaggtttc ttcaatatag tgatcactga 2747041 agctgctgtt ttgctctgga tcaagcactt caagcatagc ggatgatggg tctcctctaa 2747101 aatcagatga cattttgtca atttcgtcta ataagaagac cggattcagc ttgcccgctt 2747161 ttttcatccc ttgaataata cgtccaggca ttgctccgac ataggtccgt ctgtgtccgc 2747221 gtatctctga ttcatcccga actcctccga gtgagattct gacgaatttg cgtcccaagc 2747281 tttttgcaat tgatttggct aaagacgttt ttccgacacc tggaggtcct gccaaacaga 2747341 gaatcgggcc tttcagggat tttgtcagct tctggacagc caaatattct aaaatacgtt 2747401 cttttacttt ttcaagcccg tggtgctctt cgtccaagag acgtcctgct tctttcaaat 2747461 caagcttatc atctgtttca tccgtccacg gaagagcaac cagccagtcg atatagttgc 2747521 ggatcacaga gctttccgca gaacttgacg gaattttttc atatctgttc aattctttaa 2747581 gcgctgtttc tttcacatga tcaggcatgc ctgcttcttc gattttttcc gtcagcgtct 2747641 gaacttcgcc agttttgcct tctttatcgc caagctcttt ttggatcgcc ttcatttgtt 2747701 cacgcaagta gtattccttc tgcgtacgct ccatcgaacg tttgacgcgc tggccgattt 2747761 ttttctcaat ctccagcact tctttttcat tattaataaa atcaatgacc ttgttcagcc 2747821 tgtctttgac atcagccgtt tctaaaatat cctgcttatc ctttagttta aggggcagat 2747881 gagaagcaac gatgtctgcc attctccccg gctcttcgat atcagtaacc gcagcgtacg 2747941 tttcggccga gattttttta gaaattttta tgtactgatc aaagtggtct agcaaagtcc 2748001 gcatcaatgc ttcgtcttct gtatcttttg aatcatcttc atgaataagt tgaatgtcaa 2748061 ccgacgtgta atcctcgtgt tcattgtatt tgacgatatg ggcgcgcttg aggccctcca 2748121 ccaacacacg aatcgtaccg ttcggaagct tcagcatttg cttaattttt gtataggtgc 2748181 cgacagtgaa aatctcgtct tcaccaggtt cgtctatcga aatatcctgc tgagtggcta 2748241 aaaatatcat atgatcatgc atcattgcct gttcaagagc ctgaaccgac ttgtcacgtc 2748301 ctacatctaa atgcaaaacc atcgtcgggt acactaataa acctcttaaa gggaggagcg 2748361 ggatgctgcg ttttaattct tctgccatgt gactgacacc tccgtgactt tagtatgaac 2748421 cattataata caactttttc atccttgtac aataaacggc atggttccat tttctataaa 2748481 acagtctcct cgtagtatac cctttctttc tgatatgaaa aaggaaaaga tgtccttcat 2748541 gaaaaaaacc ctattatcaa aatagggttt aaacggattc tttattgatt tcgatatgaa 2748601 acggtttttg ttccgttggc ggattcacca aaatttcatc aagcacttct tggaacgtct 2748661 tcactgcaat aatctcgatc ccgtcaatct gctttaagat ggcctgctga ttttcatatg 2748721 ggataatcac ctttttcgca ccggactgct tggccgcttt tattttcgga atgacgcctc 2748781 cgatgggttt cacaagaccg ttcaggctga tttcgcccgt catcgcaacg gtattgtcaa 2748841 taggaatttt gtgtatcgcc gagaaaatcc ccgccgccat cgcaatgcct gctgacggcc 2748901 catcaatcgg aatccctcct gggaaattga tgtgaatatc ataatcagaa ggcttcattc 2748961 ccattgtccg gagcacggtt aatacatttt caaccgaacc cttcgccatg ctttttcgcc 2749021 tgatcgattt tgattggctg ccgatgcttt cttcttcagc tattcctgtg atgttaattg 2749081 atcctttatc ttgagccgcg gttacactta cttcgatttc cagaagcgat ccgctgttag 2749141 gcccatagac tgcaagccca tttacaatgc caacctgtgg ttcaacaccg attttttgct 2749201 cgtgctttgg agtaagctga ctggagtgaa tgacccattc aatatcctca atcgtaatgt 2749261 cctttcgatt ctccgttaca gccatccccg ctgcgatttg aatcatattg acggcttccc 2749321 gcccgttccg cgtgtagctg gtcaaaagat ccagtccttc ttcggagata tttttttcaa 2749381 ttttatccgc tgctgttttg gcaaccgttt tcagctcgtc cttttcaagc tcgcggaaaa 2749441 aaacctccaa acagcgggac cggatagctg gcggaatttc gtttggcatt ctcgtggtcg 2749501 cgccaatcaa gcgaaaatca gccggcagcc cattttgaaa aatatcatga atatgattcg 2749561 gaatttgtgt attttcctca ctgtaatacg cactgtctaa aaagactttt ctgtcctcaa 2749621 gcaccttcag cattttattc atttgaatag gatgcagctc ccctatttca tcaataaaca 2749681 gcacaccgcc atgggcatgg gtgacagctc cctgcttcgg ctgcggaatc ccagcctgtc 2749741 ccatcgctcc ggccccttgg tatatcgggt catggacaga gccgatgagc ggatcggcaa 2749801 ttcctctttc atcaaaacgg gctgttgtcg catcgagttc cacaaagaca gcctgctctt 2749861 taaacggtga ttgtttatgt ttttttgctt cttccaacac aagccgcgca gcagccgttt 2749921 tcccaactcc cggtggccca tagacaatca catgctgagg atttggcccg cataaagccg 2749981 cctttaatgc tttaatgccg tcttcctgtc cgacgatatc tttaaagctt ttggggcgga 2750041 ccttctcaga taatggctcg gacaagctga tagcgcgcat tttccgaagc tgctccattt 2750101 ccttctttga ttctttatct atcgtgacct tttgtgtcct ttgattttta agcaaattcc 2750161 aaaaatacaa accgatgatg atcccaaaaa acagctgaat aaataacgcg atccctgtcc 2750221 aactcatggt ggtccctcct gaaaaacaat ttatgtatcc aattcattcc tctgattgct 2750281 agtatctccc atagaagacg ggaataaacg tttttccgga agagttgcat gcaaaaaaac 2750341 ctcctgagtg ttaccactca ggaggtttgt gcttatcttt atgcagatgt tttatcttgg 2750401 cttacctcag tgccgtcttt taataagagg cgaggaggct ctccgtgtgt cacagttgcc 2750461 ccggtgatta cacatttttc aatgtcatca cgagaaggca gctcaaacat cacatcaagc 2750521 atgatgcctt caatgataga acggagtccg cgtgctccag tcttgcgttc aattgctttt 2750581 ttagcaattt cagaaagcgc ttcttcttca aactcaagct caacgttgtc aagctcaagc 2750641 attttcttga attgcttaac aagagcgttt ttcggttttg ttaagatcgc aaccaatgct 2750701 tcttcgtcaa gcttttcaag gcttgcaata accggaagac gtccgataaa ttcaggaatt 2750761 aacccgaaac ggagcaaatc ttctggaagc acttttgaaa gaagatcttc tttctcaaga 2750821 tcagcagctt tattgtcggc accgaatcca atcacttttt ggcctaaacg gcgtttgatg 2750881 atttgttcga taccatcgaa agctccgccg caaatgaaca aaatatttgt tgtgtcaatt 2750941 tgaatgaatt cttgatgagg atgcttacgt ccaccttgag gcggtacgct tgccactgta 2751001 ccctcaagaa ttttaagcaa tgcctgctgt acaccctcac ctgacacatc acgtgtgata 2751061 gacgggtttt cagattttct agccacttta tcgatttcat caatatagat aatgcctttt 2751121 tcggcttttt ccacatcata atcagcagct tggatgagct tcaagagaat attctctaca 2751181 tcttcaccca cgtatccagc ttcagtcaaa gatgtagcgt ccgcaatcgc aaacggcaca 2751241 tttaaaatgc gagccaatgt ttgcgccaga agggttttac cgcttcccgt agggccgatt 2751301 aatgaaatat tactttttga aagctcaaca tcatcaactt tgctgttgga gttaatgcgc 2751361 ttatagtggt tatacacagc aacagcaagt gatttcttcg cttgatcttg gccgatgaca 2751421 tattcattca aaatttcgcg aatttcctga ggctttggta cgtctttaaa ttctacttct 2751481 tcttctgttc cgagttcttc ctctacaatt tcagtgcaga gttcgataca ttcgtcacat 2751541 atatatacac caggtccagc tacaagctta cgaacctgat cttgtgtttt tccacagaac 2751601 gagcatttta attgtccttt ttcctcgtta aatttaaaca ttctttcacc ccttaatctt 2751661 gtctcacttt ttcttttacc ggcagagcaa aagaaaatga ttcttgaaac gaacgagtat 2751721 gtattgcatt ttaccatact ttccaaaaag acggtaacaa tgtgtttctg acttgcacat 2751781 tctatatgta tgacaaaaaa cagccctgca ttaactatat tgccccaaga aaaagagata 2751841 actcataatt gtacaaaaca aggcacgaat gattcgcgcc ctgttttatt agtactatta 2751901 ttatgcacca tattaacggt tttctacaag aaaatcaatt gctttgcgaa cttttaaatc 2751961 ttctttcatc gcgtcagtag aaccgatggc ttgtttaata ttttcaacag gcatgttgta 2752021 tgcttcagcc atttttgtaa gctcagcatc aacttcctca tctgatactt caaggttttc 2752081 cgctttcgca atcgcctcaa gagtcaggtt agattttacg cgtttttcag catcttcttt 2752141 catttgctct ttaagcgcag cttcatcttg gcctgagaat tgagtgtaaa gctcaaggtt 2752201 catgccttgc atttgcagac gctgttcgaa ttctttcagc atgcggtcaa gctcagtgtc 2752261 gaccattgct tgaggcacat cgatttcagc attttcagaa gctttcagaa caagctcttc 2752321 acgcaattta gcgtcagctt cgttttcttt tgcttcttct aaacgtttct ttgttttttc 2752381 agttaattca gcaagtgttt ccacttcttc atcgatatct tttgcgaatt catcgtcaag 2752441 ctcaggaagc tctttcgctt tgatttcgtg aattttcact ttaaacacag ctggtttgcc 2752501 tgcaagatct tcagcgtggt actcctcagg gaatgtcact tcaacatcct tctcagcacc 2752561 tgcttcaagg ccaactaatt gatcttcgaa gccagggatg aatgaaccag aacctacttc 2752621 tagagagtag ttttcagctt ttccgccttc gaaagcttcg ccgtcaacga atccttcgaa 2752681 atcaagaaca actgtgtttc cttcttcaac ggcgccttct tcttttacaa caagctcagc 2752741 ttgacgctct tgaagggctt ttagttcgtt ttgaacatct tcgtcagtta cagttgtgtc 2752801 gtctttttca atgcccaggc ctttgtattc gccaagcttc acttcaggtt ttactgttac 2752861 tttcgcagtg aagattaagc tttcgccttt ttcgattttt tcaacatcga tttcaggacg 2752921 gtctacaggc tcgattccag cttcttcaac cgctttaggg tattctacag gaagaagaat 2752981 atccaaagca tcttggtaaa gagcttctac gccaaagcgc tgttcgaata atccgcgagg 2753041 aattttacct ttacggaatc caggaattga aacttgtttt actacttttt taaatgcatc 2753101 atcaagtgct gttttaaacg tttcagcatc aacttcaacc gttaaaacgc cttcgttgcc 2753161 ttcttgtttt tcccatttta cagacatgtg tttccctcca aaaatctatt caggttgtgt 2753221 cggtcttcca ttctaaagca atcattcggc ttcgtccaac aaaaacaaag ctgccaaaga 2753281 tcagaatcat tatgtataga tgttaataat gaactgcaaa gcctgtccaa ccgtatttct 2753341 tataacccgt tatacacaaa tacaaccact atattataac ataacacata gcgctttcaa 2753401 ctatatggcg cgatttacaa ataagaaatt tcttcaatat cttttaacat tgtgcaagct 2753461 tcatcgagtt ctctgtctgt aaattcatac atcatatgaa gttcttcgct ttcaatttca 2753521 atcccgtgca tctcgtaacc gactttatga agggcagccg cccaaaggtc agccgacagc 2753581 aatttcggct ggaacggata taaaacgtac aaatgtcttc tccacaattc ttctactgct 2753641 gcatataagg ttggattttc atttccaagt gtctcatcta gcaccctgag aacacggtga 2753701 agaatcggcg cggcatcagg cggaacaatc tctgacggtt caattgtcaa cgactcgcca 2753761 aatttactaa tgtgtacagg tttactgtac tcatgctcag ccaacagcat gacaatcatc 2753821 gttttgataa tcggatgggc tgaggggtct tggaggattg ttttgagcaa tcctgtatac 2753881 tttgctacgt tacggtcttt taaggaatga atgagattca tttgctcctc agggcttgcc 2753941 agcactttct cggtgtcaat tgtatcctca tattcttcgg cccaagcctc gtcctcacga 2754001 tccggatcgg tcattttccg gctgaaatcc agcagcttat aaaattgctc ggcactttct 2754061 gccggcagct gattttcttc caaaacggct tcaatggtgc ttttgacttc ttcgtacttt 2754121 ttgagctgaa ttaagatggt catgtacacc tgcaaaaccg taaaataatg gccataacct 2754181 tctttgagca tcttctcgca cacgctttct gcctcttcca gctcgcccag ctctaaaaag 2754241 cagatggcca tccctaagtg aagatcggat tcagtatcat catatttcat cgcttctgaa 2754301 aacagttcaa gcgcttcttg atactttttt tccttgagtg atgacatccc tttttccaca 2754361 aggcggtctt tcagatgagg aaaaggaata atttttgcgt ttttcttgtc atgcgtcata 2754421 cctatattcc tttcaggcat ttattttgtt caagtgtatc aacacctgtg aacaaaaaca 2754481 agaaatgaaa ggtttcacca ggcaaaaaaa gccgccggac aaataccggc cgctttttca 2754541 ggcttgaagc caagagcttc tttgtgattc aaattgcttg atttcatctt ccagcagcag 2754601 cgttaatgaa atttcatcat atccgttgat cagcatctct ttccaatgcg gatcaacttc 2754661 aaatgaaatt tgattgcctt cactgtcatg aatcagctga ttttcaaggt caacagtcat 2754721 ttgcaatgac tggttttcat actggccgac aagctgtttc caattgtcat atggcatgcg 2754781 gatcggaagc atgccgtttt taaagcagtt ctgatggaaa atatcagcga atgacggcgc 2754841 aatgataatt ttaaacccat aatcatcaag tgcccacgga gcgtgttcac gcgatgaccc 2754901 gcagccgaag ttttctcctg ctattaaaat ggaagctcct tgataaacag gctggtttaa 2754961 ttcaaattca gggttcggtt caccattcgc atcatatctc cagtcaaaga atgcaaaacg 2755021 tccgtagcct gttctttcaa tcctcttcaa aaattgctta ggaataatct ggtctgtatc 2755081 cacattgatc cgatttaata cggctgcttt ccccgtatgt gatttcaaag gttccatctc 2755141 gcgcactcct tacacaactg ttttttcctg ataaaacttt ctgacatcaa cgaagtgtcc 2755201 gtgaatggca gccatcgcag ccattgccgg gctgacgaga tgtgttcttg caccttttcc 2755261 ttgtctgccc tcgaagttgc ggttagaggt tgatgcacag cgctctccct caggaacaac 2755321 atcattattc atactcaaac acatgctgca gcctgactct ctccattcaa atccagcttc 2755381 caagaaaatc tggtcaagcc cttctttttc agcctgaagc ttcacgcttt gggatccggg 2755441 cacgacgatg gcccttacgc tgtcagctac cttcttccct ttgatcatgt cagcagcctg 2755501 tcgaaggtca gtcatgcggg aatttgtgca ggaaccgata aatacgtgct ccactttaat 2755561 gtcttcaatt ttttggtgag gagtcaatcc catatattca taagcacgaa tcgcttcttt 2755621 tttatcgtct tctgcagaaa agctttccgg cgcaggaact tcagaatcga caggaagaac 2755681 cattcccggg ttaatgcccc atgtcaccat aggggaaatt ttgttgccgt caaggacgat 2755741 agatttatcg taaacagcgc ccgggtctgt gcgcagcgcc ttccattcct ctacggcctt 2755801 gtcaaattct tcgccttttg gcgtgtactt gcgatttttg caatattcaa acgtcacctc 2755861 gtcaggtgca atcaaacctg ctcttgctcc tgcttcaatt gacatgttac aaacagtcat 2755921 tcgttcatcc atcgtcatat ttctgaatac ttccccagtg tattcaatga cgtagcctgt 2755981 gccgaatttc acaccgtatt tgccgatgac agcaaggatg acatcctttg ccgttacccc 2756041 tttttgaagc gttccatcta cgcgcacttc aagtgttttt ggacgctgct gccaaagtgt 2756101 ctgtgtggaa aggacatgtt caacttcact cgtcccgatt ccaaatgcaa gagcgccgaa 2756161 agcgccatgt gttgatgtat gactgtcacc gcacacaatc gttttccctg gaagcgttaa 2756221 gcctagttca ggtccgacga catggacaat cccttgatcc acactgtgaa gatcggcaag 2756281 gcgcacgcca aattcctcac agtttctttc aagcgccgtt acctggcgtt tcgcaacttc 2756341 atcctttatc tcaaaacgat tgacagtcgg gatgttgtgg tccattgtcg caaatgtgtt 2756401 ttggggtctt ctgacctttc ttcccttttg tctcaagcct tcaaatgcct gaggagacgt 2756461 cacctcatga atgaggtgca aatcaatata gagaagatcc ggctttccct caccatgttt 2756521 tacaatatgc tgatcccaaa tcttttcgat gattgttcga ggcatcatct tttatttcct 2756581 ccctctacct agagctaaga ccgcttaacg taagctgtca cacattagaa attgtatttt 2756641 cactcatgat tgctgcctta acttcctctg taatggcctg agtgctgctg aactcttcac 2756701 tccgtgccaa gtctcttgtt ctttttccag aagccaagac tttgtttacc gcatcttcta 2756761 cagctttcgc ttcctcttca agcccgaaag atgttctcaa aagcattgcc gctgacaata 2756821 tggctgcgaa cggatttgcc atccctttac cggcaatatc aggcgcggag ccatgaacag 2756881 gttcaaacag atgaaggcca gagcttgata ggctggctga cgggagcatt ccgagcgagc 2756941 ctgtaagcat ggacgcttca tcgcttaaaa tatcaccgaa catattttca gtcaccacga 2757001 catcaaattg attcggtgca taaattagct gcatggccgc gttatccaca agcatgtgct 2757061 caagcttcac atcaggaaat tcttgtgcaa cgtcctcagc cacttcacgc cacagccggc 2757121 ttgattcaag aacattcgct ttatctacag aggtcacttt gccttttctg gctgccgcca 2757181 ttttgaagcc ctctctgatc actcgttcaa tttccgttcg cttataaaac agtgtatcta 2757241 ctgcttcctg ctcaccttca gtgtttacat aacgtttgct cggctggccg aaatacaagc 2757301 cgcctgtgag ctcacgaacg ataacgaaat caacattatc tatatattct tttttcaaag 2757361 gcgaagcgtc agaaaggctt tcaaatacct tcacaggccg caaattcgca aacaaatcaa 2757421 gctgttttct gatgctgagc agcccttttt ccggtctcag ttccgaagga ttttgatccc 2757481 atttcggtcc gccgacagca ccaagcaata tcgcgtctgc atttttacaa gcagcaacgg 2757541 tttcctccgg gagggggtta tgatgttcat caatagccgc ccctccaatc aggccatatt 2757601 caaattcaaa ttcatggtta aagcgttcgg caacactttt cagtacgtct gtcgctgatt 2757661 ctaatacttc agggccgatc ccgtctccgg gcaatagagc aatacgtttc ttcaagttaa 2757721 ccgttctcct ttcttttatg atccgacagc tgtgtggttt ttcaatccgc tcatattcga 2757781 ctggaaaacc aattgacggt ttactgcgtt caaataggct ttcgctgatg cttctaatac 2757841 gtcttgcgct atgccccgcc ctgctgattc ttttccgttc accaaaactc ttacatacac 2757901 ctgggcaaat gcatcttcgc cttttctatt agactgaatg cggtagtcta agagctccac 2757961 atccttatcg atgcagcgct caagcgtatt gtagattgct tccacgcttc cagctccagt 2758021 tgcagcttcc tgaataagct gtgcgttttc ttgatttttc aaagatagag tagccgtagg 2758081 gacctgactt gttccgtaat gtacttgcag agaaagaaat tcatacccaa tcttgcgatc 2758141 tgttactttt tcttctaaaa taagagaaac aagatcctca tcagtgattt cttttttctt 2758201 ctcagtcaac tctttgaaca tcgtaaagaa tttattaatc tcttcactgt caaattggaa 2758261 tcctaaagca gtcagccggt ctttaaatgc gtggcgtccg gaatgtttac ctaggacaag 2758321 cgcatctgcg gttacgccga caagctccgg tgaaataatt tcataagtcg atttttcctt 2758381 taaaaagccg tcctgatgga tgcctgattc atgagcaaat gcattatctc caacaaccgc 2758441 tttgttgcgc gggacagcca tgcctgtcag tttgcttact aaatcacttg ttctcttaat 2758501 ctcgttcagc gtaatacctg tttcgacttg gtagaaatct tttctggtat ggagggctac 2758561 ggcaatttcc tctaatgccg cgtttccggc tctttcaccg atcccgttca cagcgcattc 2758621 gatttgatca gcgccatttt caatcgcagc aagagagttt gcgactgcca ttcccaaatc 2758681 atcatgacag tgggctgaaa gctttgcttt gtgaatgttc ggaacgtttt ctttcatata 2758741 tttaaagata tttccgtatt ccgccggggc caggtagccg acagtgtccg gaagattgat 2758801 aacactggcg cctgcgtcaa tcactttctc gacgatttct gctagaaacg gcagttcagt 2758861 gcggcaggca tcttcagctg accattgcac aatcggaaaa cgttcttttg cgtatttcac 2758921 cattccaact gctctttcaa tgacttgttc acgtgtcatt ttcagcttgt gcttcaaatg 2758981 aatgtccgat gtcgcgataa atacatgaat tcttggttga gcgccatcct ttaacgcttc 2759041 ccaagcagca tcaatatcac cttttacaca acgggccaga ccagttactg aacaattttt 2759101 aatggttctt gcgatttcct gaacagctaa aaagtcacct cgggacgaag cgggaaatcc 2759161 cgcttcaatg atgtctgccc cgagtctttc gagctgctta gctatggcaa gtttctcctg 2759221 tgtattcaag ttcactccag gggactgttc accatcacga agcgtcgtat cgaaaaaatt 2759281 aattttgcgc aacggagacc accgcttcct tcttcttgcc ttgtttcaca aacggcatca 2759341 tttcacgaag ctttcttccc actacttcga tttgatgttc gttctcgctt gcattgatag 2759401 cgttgaaacg aggacggttt acttggtttt cgacgatcca ctcttttgcg aatgtaccgt 2759461 tttggatatc ttttaatact tctttcatag attcttttac tttggcgtcc acaacgcgag 2759521 ggcctgatac gaaatctccc cactgtgctg tgtcagagat tgaatatctc attcctgcaa 2759581 gtccttcttc gtacataagg tctacgatta atttcagctc atgaagacac tcgaagtatg 2759641 caagttcagg ctgataacct gcttcagtta aggtttcaaa tccggctttg acaagcgcgc 2759701 ttaatccgcc gcaaagaact gcttgctcac cgaacaaatc tgtttctgtt tcttctttaa 2759761 atgtcgtttc taatacgccc gctcttgcgc cgccgattcc tttagcataa gcgagggctt 2759821 tgtctcttgc ttctccagtc acatcttgat agattgcgaa caatgcaggt acgccagctc 2759881 cttgctcata tgttcttctt accaagtgtc ccgggccttt aggggccact aagaatacat 2759941 ctacatccgc cggaggaaca atttgatgga aatgcacgtt aaatccatga gcgaatacta 2760001 atgattttcc tgctgtcaat tcatctttga tttcagcttc gtatactttt tgctgctgct 2760061 catccggaag cagaaccatg atgatttcgg cttgggctgc cgcttctttt actgaaaata 2760121 ctttatgtcc gtcttcttgg gcttgagtga aagattttcc ttgtctaaca ccgacgatca 2760181 cgtctactcc gctttcttta aggttcaggg catgtgcgtg gccttgcgaa ccgtacccga 2760241 taaccgctac tgtttttcca gccaatacgt tctctttgat atcaccgtta taatatactt 2760301 ttaccatttc aatctctccc ttgttatgtt ttatacaata gatattgttt tattggatga 2760361 cgccttttgc tgggttcccc tcgcaaaagc cgttgtacct gttctcgcga tttctttaat 2760421 gccataaggt tttaataact caataagcgc ttcaattttg ttagattcac ctgtcacctg 2760481 aacaacgatg ctgtctctgc tgacatcaac gacagaggct ctaaacggtt ctatgattcc 2760541 attaatctct gttcttgttg aaggtgcgga gacaaccttg attaaggcca gctccctctg 2760601 gacaatcgat tgatttgtga tgtctgtgac tttcagcaca tcaatctgtt tgttgagctg 2760661 tttcgttaac tgttcaacat cattttcacc ttcaacatga acgacgaagg tgattctgga 2760721 aacgccggct gtttctgtgt gtccaactgt aatgctttca atgttgtaat gcctttttgt 2760781 gaatagaccg gtgatccggt ttaacacccc ggagcggttc accacagtca atgtgataat 2760841 tcttttcaag gtttcacccc caccatttca tgcagccctt tccccggagc caccatcggg 2760901 aatacttttt cttcgctggc aacccgcacg tcaatgacaa caggttctct tgatgttaat 2760961 gcctcttcca gcttttcctt tgcttccgct tctgatgaaa ttctgatgcc tttaatgccg 2761021 tatgcttcgg acaatttgac gaagtcaggc tgagaagcga atttagattc tgaataacgt 2761081 tcttcataga aaatttcctg ccactgtctg accattccga gacaagcgtt atttaaaatc 2761141 actaccttga ccggaagatt taattcgcga ataacatcga gttcttgaag cgtcatttgg 2761201 aatccgccgt ctccgacaac cgcgacaaca gtagcatctt tttcggccag ctgtgcgccg 2761261 atcgccgccg gaagaccgaa tcccatcgtt ccaagtccgc ctgacgtgac ccatttatct 2761321 gctttttgga acggataaaa ttgcgctgac cacatttgat gctggcctac atccgttgcg 2761381 acaatggcct ctccttttgt aaattgatga atatattcaa tcaatttctg aggtttaaaa 2761441 ccttcttctt cattatctac ataccagagc ggatactctt ctttccattc tgcgagctgt 2761501 tttttccatt cgcttgaatc gctttgtttg ccgtcttgtt tgatcagctc ctgcaggaca 2761561 attttgctgt ctccgactac aggaatctgt gttttcatga tttttccgat ttcagctgga 2761621 tcaatatcga tgtgggctat ctttgcgttt ctggcaaagt gtttcaggtt tcctgtgaca 2761681 cggtcatcaa aacgggcgcc gatactgatt aatagatcac attcatgaag ggccatattg 2761741 gctgtataag taccgtgcat tcccgccatc cctaggaaaa gcggatggtc agccgggaag 2761801 cctccgagcc ccaaaagggt gtgtgccaca gggatttgct gctgttcagc ataatttttt 2761861 aattcttctg acgcttttcc gtgcagtacg cccgcacccg ccaggatcac cggttttttc 2761921 gcactgctca cggcttccac aagcttgcgg atctgcaaat aattcggctc tgttgtcggc 2761981 tggtatcccg ggagattcat ctcatgatcg tagctgaatt ctccttcaat tgttgctaca 2762041 tctttcggaa tatcaatcaa tacaggtccg ggtcttccag ttgttgcaat atggaacgct 2762101 tctttaatga tgcgcggcag atcttccggc tggcgaacct ggtagctgtg ttttgttact 2762161 ggcatcgtaa tccctaaaat gtctgcttcc tgaaatgcat cgctcccgat tacagaggtt 2762221 gctacctgcc ctgtaaagac gactaacggc aatgaatcaa tcatggcatc agcaaggcct 2762281 gtaacaaggt ttgtcgctcc cggccctgac gtggcaatga cgacacccgg ttttccggag 2762341 acccttgcgt atccctccgc tgcatgaatt gctccttgtt cgtgacgggg aaggatatgt 2762401 accaaccctg aattgtatag cttatcgtaa atcggaagca cagccccgcc cggataaccg 2762461 aagatcattt ctactttctc tttttttaat gattcaatca gcattaatgc tccgctcatc 2762521 gtctgtgtac attcggcaga tgctgaatcc acctgtacat tagtccccat tttagttcct 2762581 ccttttggat tttcatcctt taaagatcat cttttcatta gctagatagc tgattattca 2762641 ataaaaaaag cccttccgcc cacaatcagc cgcgcagtaa ctgcgatagc taaaaggggc 2762701 gaaaaggctt ttctttccgc ggtaccaccc ttgtttacgg cctgttaatc ggccgtctca 2762761 tggatatttc tatccgcttt agtaacgagt gaatcaagtt cacccggcca agtcctactg 2762821 tcatttcaga ctggcactct gaggcgagtt caccttgtaa agcttcgccg gttctcagct 2762881 aacccggttc tctgtggaaa actttatcaa ggctacttat cctcatctgc gcttttcata 2762941 ttcagccttc ggaacggctt tccagctgtt caagaaggtc gtttgttttt cattttttta 2763001 gaatcatact gcgatgattt tcgcttgtga agcttgcatt tatcttttgt tgaactcata 2763061 ttacgccgct ttggacgcag tgtcaacagc attttttaaa attattagac aattttgatt 2763121 aatcaatcta tattgtatac gctttcatta ttggtacaaa aggaattgca aatgttaaaa 2763181 gtttttataa tttttttatt aatctatcaa gaatacacca gaattattta attttatata 2763241 aacatggaag attttataac acgatatggt tcgtatatgg attgagtctg acagatcatc 2763301 ttgcaatcca tttcaatttc ggataggcac ttctcttgtt ccctcggcat acattaatga 2763361 tatcttgcaa agaaaaggtg atacgatgaa taaatcattt gcagacatgc aaggatttcc 2763421 tgcgggcttt ccaagcttcc ccaactttcc gcagcagtac tatcctgctg tccctccctt 2763481 ttaccagcaa agccagcagc catttggagg ctacggatac ggacagccgt tcagtcaggc 2763541 atacagcccg ttaaccactc cctctggaat gtactcctca ttcccatacg cttcaggatt 2763601 ttacggacag caattttcag gtgcaggctt tagcggccat ggcggcagct taagtgctcc 2763661 agcgatacat gccggcggat tcagcggggc gccaggcgta cacggaggct ttagatatta 2763721 aagaatacca caagggccga acatctattg cggtcctttt attgttttaa aacgacttca 2763781 caagtacagt cacattttct gtctttatat ttggaaacag gatggaatat gattaagatg 2763841 aattgaacga tattctgcac aatccgtaag ttttcgagga ggaataaaat tgcatataaa 2763901 aatagacgat ttaactggac gtcaggtggt ttcactggtg aatgagcatt tacatagcat 2763961 gacgcttatg tccccgccag aaagcattca tgccttaggt ctagaaaaac taagagggcc 2764021 tgaaataaca ttttggagcg catgggaagg tgatgaacta gctggctgcg gagcgctaaa 2764081 agaactggac acccggcatg gagaaatcaa atcaatgcga acatctgcat cacatttaag 2764141 aaaaggcgtt gccaaacaag ttctccagca catcattgaa gaagccgaga agcgaggcta 2764201 tgagcggtta agcttagaaa cgggttcaat ggcttcattt gagccggcaa gaaaattgta 2764261 tgaaagcttc ggtttccagt attgtgaacc gtttgcagac tacggtgaag atccaaacag 2764321 tgtgtttatg acgaagaaat tgtgagacgg ctttataagg atagataagt gcaggggaag 2764381 gtctgtctta tctatctttt tttatattca cacatttttc acctttatga tacacgccaa 2764441 tgttttcaat tttgtttaat tcaaagaaca gcgggaatta caaacgacat gaacgatatc 2764501 atgcaaattc ataaaggagg agattgatat gaaaagcata gttggtgtat atgaaactcc 2764561 gcaggaaacc atcgcagcga ttgaaggctt acttacaaaa ggctatgatt ctgatgacat 2764621 ttctgttgtg acaagccggc gagatacaga ttatttggag tcacgtacag gaacagaagt 2764681 caatcaagct atcgatgcac atcaggacga atctgaatct tttttcgata aactgaaaga 2764741 ttatttcaca atggatgata ctgctacaca cagcaaagca ttatccgact tggatattaa 2764801 aactgatgaa atagacaagt atcaagaaga tttggatgac ggaaaacttc tggtagccgt 2764861 cgatacagat gcagatgtaa ttgctcctat tgataacggc aatgcccttt caggcggctt 2764921 ttcaagcaca aatgaattgg attatacaac gaaagaagaa aaaacgatgc cgctccggga 2764981 agaacagctg aaggtcgata aggaagacgt tcaaaccggc gaagtagaaa taggaaaaga 2765041 agtgaaaaca gaaaaaagag atatggacat tccggtgaga catgatgaaa tttatgtcga 2765101 acgccgtcca gtggatgaaa ataaaacgga cgctgctccc gtcaacgatt cggaagagat 2765161 cagagttcca atcgttgagg aaaagctgga agtgactaaa aaaccggttg tcactgatga 2765221 agtggttgtc ggcaaacgca ctgttgaaga aaatgaacat atttctgaaa ctgtgaaaaa 2765281 agaagaacct cgtctgaata aagaaggaaa agttgacggc ttggatgatg atccgttaaa 2765341 taacaaatga aaatcataga ccgacaacaa aaaacctcaa atcctaaatg gatttgaggt 2765401 ttttcttttg gtacgtccca ggagagattc gaactcccga ccgacggctt agaaggccgt 2765461 tgctctatcc agctgagcta ctgggacacg ttttgttttt ttgtttttcg ctttaactat 2765521 cagcgacaag atttattata tatgggatgc aataataagt caacggtttt ttagaatttt 2765581 tttcatgagg aagaaaattt tcttcctcat gacattttca tagtgtgact cgattttgca 2765641 gatcctcaat ttcattgcct gcttggtcgt aaaaacggac tgtcgcagca tcattttcta 2765701 atgtcagtat agcatagctt tctgtcctgc gcaccctcgg aagccggatg ctgcctgggt 2765761 taatcatcag ttttccgcgc agcacttcgc ttcccgcgat gtgcgaatgc ccgaagcaga 2765821 taacatccgc cccgagctcc tctgcacgat agtatacgtt taacaaggtc tgttttatac 2765881 cgtgaaggtg gccgtgtgtg actagtattt ttcttgagcc ggcagtcaga agaagctcgt 2765941 ccttaaaatc gccggcaaaa tcgcaattgc cttttacaac cgcataaggc tccaatgcag 2766001 gatgcctcgt ctcaagctca gagtccccgc aatgaatcat gagatcaact tctgcctcat 2766061 gccgtttcgc aatggtttgg agttcttctt caagcccatg gctgtcactg ataatcagca 2766121 cgttcatgta caagcttcct ccttatgcct ccaaaagctt agacagcttt ttaagcgcgt 2766181 cagccctatg gctgatttta tttttttcat cacttgtcag ttcagccatc gtcttatctt 2766241 tatctttcac gataaaaatt gggtcatagc caaagccata ttctcctctc ggttcttcag 2766301 caatataccc ttcaacatgg ccttcgactg tttttgtttc ctctccggga atactcacgg 2766361 ccagtgcgca gcggaaacgg gcggtgcgct gttctttttc gatacctttc agctcgctga 2766421 gcactttttc gatatttgcc tggtcgtctt tctgttcccc tgcatagcgg gctgaataaa 2766481 ccccgggtct gccgccaaga ttatcgatgg atagtccgga gtcatccgca atcaccattt 2766541 tgttcactgc tttggcaaca gcttccgctt tcataatggc attttcttca aatgtatggc 2766601 ctgtttcttc aatttcctct gtgaatccaa tttcagctaa agatttgaca tcatagcctc 2766661 ttggctcaag aatttctttg aattccttca cttttcccgg attatgtgtt gcaataattg 2766721 cttctttcat gatgatcaag cctttctgtc tttatttcag ttctggcaga gaatcaccca 2766781 gcacttcttt ttgcttgtca atcagctctt ggattccttt ttccgcaaga cccagaagac 2766841 cgttcagatc ctctctagaa aaagttgcct cttccccggt tccctgcaat tccacaaaac 2766901 ggccgctgcc tgtcatgatg acattcatgt caacttcagc agaggaatct tcttcataat 2766961 ttaaatctaa caaaattccc tgttccttat caattccaac agagattgca gcaagaaaat 2767021 cagtgatcgg atttgtcttg attgttcctg ctttgatcag cttgccaatc gcaatcgcca 2767081 tagcaagaaa tgcgcctgta atggaagctg ttctagttcc tccatcagct tgaatgacat 2767141 cacagtcaat ccaaatcgtc cgttcaccga gcttttccag atctacaaca gctcgaagcg 2767201 cgcggccgat caggcgttgg atctccattg ttctgccgga aattttcccc ttagaagatt 2767261 ctctgattgt tctttggttt gttgcccgcg gcagcatgct gtactctgct gtaatccagc 2767321 ctttccctcc gccccgcaaa aacggcggta cgcggtcctc aacagacgcg ttgcagatta 2767381 cctttgtatt tcccgctgtt attagaacag aaccttccgg atggctgata aaatccaaat 2767441 cgaatgtgat tggacgcagc tcatcgtgtt gtcttccgtc atgtctcatg ttttacctcc 2767501 gattgtatgt acataaacca tttttgtccc ggaattgaat aaagaaagag gcagccggaa 2767561 cgctaacctc tttcttccta gtatatcaaa aatcccaatt taaaaactac ccgtattcac 2767621 ttgagatggt ctggagaccg gttctgtgag cttttcgcct ttttcattta ccagctctga 2767681 ttttccgttc actttaacag agacgctttt tacatccggc tgctccgtta acgtcagcac 2767741 aatgctgttc agcacttctg aagaaatcat tttcgtcttc tcatcggcgc tgccgaatat 2767801 agattgattg aaatccaacg tcacgcgccc gtctttgatt ttcggtttgc tgaccagctt 2767861 tacatcttca ctgaagtctg ttaacagccc gctcaccttg ctcggccctt tagccaattc 2767921 attaatggct gctgtgatgt cgtctttttc cgaattgtcg attcgtttgg tcaccggcac 2767981 gtagtattca ctgtcttcat tttccgccaa atagtagact gtcagcggat gggtagcagt 2768041 gagatcattt acaccggctg tttccaaatt aatgccgtct ttgcggctta aatcatctga 2768101 gatcggcgtc cctcctacag gcatctcctt cagttcatgc ccgtttattc tcagcttcac 2768161 tttatctatc gaactaaatt gcgtcagcgt ccacgtcaca gattgaacga ttttctgttc 2768221 gtcttctttc ttataatttt tgaactcatt agagaaatca gctatcgccg ttccatcttt 2768281 tttgatgtca acgttaacgg tggtgtcagc cggcaataca gctctgaagc cattcggaag 2768341 aatttcagac acaggcccgc cctgtacgag gtattcaagc gcctgcttag ccgtgctctc 2768401 acttttagga agaggcagcg tttgcgcaac aacatacccg tttttatcaa tgagataaag 2768461 ctccctcata acagtagatg aggcttgatc cgcttttgcg gtatcgcttt tttcactttc 2768521 tgtttttttg gctgctgttg tatttgaatt ggcacccgct tcatcgttca cgaatgtaac 2768581 gtcttgaggc ggatcaattt cctcggctgc cttatcagat tgaaacaaac cgcatccgga 2768641 taaaagcaag gcagaggtga gacaagtggc accaatgact gcaggtcctt ttttcagcat 2768701 acttttccct cctaaggatg tttgtactat tatgtatacg agcctcttta ggaaatagac 2768761 cgaagaattc cggcaaaaca gaaaaaaacc cgcaacatac cgttgcgggg aaaactatct 2768821 tttaatcggt tcttgcagtg agatacattc cacatgcccg acttcatggc caaaccaatc 2768881 gtctgcgatt tttgcaaact gatcacgcgc ccctgttgtc aggaactgat gatccggggc 2768941 aatcggagac tggttcagca gccctttata agagagaatt gtgctgactt cccgggctgt 2769001 ttcatcgccg gacgaaataa tgtttacgtg ctctcccata tatctttgaa tggcttcttt 2769061 taaaataggg taatgggtgc agcctaaaat cagcgaatca attgatgtgt cttttaacgg 2769121 atacagcgag gttttaacaa tctcgtctgc tgttttgtcg agaaacttcc cgctttccac 2769181 aaaaggcaca agcagcgggc aggcaaggtt ttcaaccttc aaatcagggt ttaatgccaa 2769241 aagcgcttct tcgtatgcat tgctcttaat cgtattctct gtgccgatga caccgatatg 2769301 ctgattatcc gtcactttta tcgctgctct cgcaccaggc tggatgactc cgaccaccgg 2769361 tataccgacg ctgcgctgga tgtcatccaa agcgatcgct gttgctgtat tacaggcgat 2769421 cacgagcatt ttgatgtggt ggttttcgag taaataattc gtcagctccc acgtatattg 2769481 aagcacctct tcttcagggc gcggcccgta aggacaccgt ttcgtatccc cgacgtagat 2769541 aatattttct ttaggtagct gtctcatgat ttccttcgca acggttaaac cgccaacccc 2769601 ggaatcaatg actcctattg gttgttccaa caaaatcgcc tcattttctc ttcatttcat 2769661 gctgcagttt catcaaagat ttttcgaaga tggctatttc ttcatctgta aacgattcga 2769721 acatatcacg cagatattcc tgtctttttg taatgacctc ttggataatc cgttctcctt 2769781 caggcagcag atgtatcctg acaacacgtc tgtccgccgg gtccttgacc cgctcaacaa 2769841 gctcattttt ttgcatgcgg tcgattaagt ccgttgtcgt gctgcatgcc agatacattt 2769901 tgcccgataa ttcaccgatt gtcatatctc ctaattcata aagccattgc aagccgacaa 2769961 attgcggcgg cgtaatcgca tattggttaa ggatttctcg tcctttttgc ttaatgatcg 2770021 cggcaatgtg gcggagtgac ttttcaatat ccgcaacatg ctccaaaggt tttgatgtca 2770081 tttgtccatc cctcactcaa ggatctctta cgcacaaaag cgttccgtgt ctattttcct 2770141 tcttttttga agaaaatgca agactcgcag gagagaaata gaggacttta gtcaaacaac 2770201 atcaagaaat aaaatttaat ttatgacttg cctacgtttt gcacagcatt ccaaatatgg 2770261 tttcgaatgt tccaaacaaa cagcaataac cggctccttc caaaagaagg aataccggca 2770321 aggattaaag ctctagctca cccattctaa gaagctcaac aacggcttgc gaacgccctt 2770381 tcacacccaa tttctgcatg gcatttgaaa tatggtttcg aacggttttc tcactgataa 2770441 atagctcgct tgcaatctcc tttgttgtct tatcttgaac gagcaattcg aacacttctc 2770501 tttctctttt cgttagcagc ggcttcgatt gaaattcttt ctccttcaag tattgtaacc 2770561 ctccttgcta aggtgagagc gaatcagaaa cgaatgggtt ttgatatagt cgagatatca 2770621 tatgtaagaa gggcgcagga ggtgacgttt acaagataat tagtttatcg tgtatgaaga 2770681 agcgtttctt tctcctcatc cgtccagctg acagccttgc cgctttcctt tgagacttga 2770741 accatcacga ctgccccggt gaagcagggt tcgccttcga ggttctctcc gagatagtgc 2770801 aaggtaagag atgaactgcc gactgcgctt gttttcacat agatgcgcaa ctcttcataa 2770861 ggcatgactt ggcgcaaata atcgcattgc tggcttgcca cgactgtcat ggtctgtttg 2770921 ttttcactca tcatattcag ctttttaaaa taagaaatcc gcacctcctc aaaatatata 2770981 aaaggggtta cattattcat atgcccaaac atgtctgtct cggaaaatct tacggatacc 2771041 ttattgaaaa aagaaaagga tgttttccat tcttgaaacg gcatatcaat ataagcggga 2771101 agcttcatct tttttcatct ccttattgtt taaaaaaacc tctcccatgc ggaagaggtt 2771161 ttttcttctt atactctgtc gcttccgaag aaattgcgga acgcttgtaa gtttgtatct 2771221 ctattcaagg ctgcaatcga agtggtaagc ggaatcccct tcggacagga ttgaacacag 2771281 ttttgcgagt tgccgcaatc tgcaaggccg ccttcatcca ttaatgcttc taatcgttca 2771341 gatttattca tggcgcctgt cggatgcgcg ttaaacaggc ggacttgcga catcggtgca 2771401 ggccccatga acttcgattt gctgttcaca ttcgggcaag cttcgaggca gacgccgcat 2771461 gtcatgcatt ttgataattc atatgcccat tgacgacgtt tttccggcat tctcggcccc 2771521 ggtcctaaat cgtacgtacc gtcaatcggt atccacgctt ttactttttt caatgaatca 2771581 aacattctgc tgcgatcaac ctgcaaatca cgaacgactg ggaatgtttt cattggtttt 2771641 aaacggattg gctgttcaag ctggtcaata agcgccgtac aagactggcg gggttttccg 2771701 tttataacca ttgaacatgc gccgcatact tcctcaagac agttcatatc ccatgtgaca 2771761 ggggttgtct tctcaccttt gacattaacc ggattccggc ggatttccat cagagcggaa 2771821 atgacgttca gattcgggcg gtatggaatc tcaaattctt catcataagg cgtgctgtca 2771881 gctgtatctt gacgtgtgat aataaatcgt atggtttttt gttcactcat gattatttcg 2771941 ccaccttctt cttcgagtaa tcccgtttcc gaggcgttat cagtgataca tcgacatcct 2772001 gatactcaaa ttccggcgct tcatacgggc ttacatgttt agccattgtt gttttgagcc 2772061 attcatcatc attacgttca ggataatccg gtttataatg ggcgccccgg ctttcattac 2772121 ggttgtatgc gccaagggta atcaccctcg caagctgaag catgttcgag aactggcgtg 2772181 tgaacatcgc tccctggttg ctccattttg tcgtgtcatt gatgttgatc tttttgaagc 2772241 gctccattaa ctcctgaatt ttgtcatccg ttttcaaaag cttgtcatta tggcggacaa 2772301 ccgttacgtt cgccgtcatc cactcaccga gctctttgtg aagaacatag gcattttcgg 2772361 ttccgtccat actcataata tcagcccatt tttcttcttc tttcttaacg tgagcgtcga 2772421 ataaagatga agacatgtct tccgctgaag attctaagcc gtttacatat ttcaccgcat 2772481 tcggaccggc caccatgcct ccgtaaatcg cagacagcag ggagttcgct cccaagcggt 2772541 tgccgccgtg catagaataa tcacattccc cagccgcaaa cagtccaggg atatttgtca 2772601 tttgatcgta atccacccat aaaccgccca tagaataatg gaccgccggg aagattttca 2772661 ttggaagctt acgcgggtcg tctcccatga atttctcata aatctcaatg atgccgccaa 2772721 gcttaatatc aagctctttc ggatctttat gagacagatc gagatatacc atgttttcac 2772781 cgttaatacc gagcttctgg ttcacacaca catcaaatat ttcgcgtgtc gcaatatcac 2772841 gcggcaccag gtttccgtat gccggatatt tttcctccag gaaataccat ggtttgccgt 2772901 ctttatatgt ccacacgcgc ccgccttcac cacgcgctga ttcactcatc agtcttagtt 2772961 tgtcatcgcc cggtatggct gtcgggtgga tttgaatgaa ttctccgttt gcataatacg 2773021 ctccctgctg ataaacgatt gacgcagcag atcctgtatt aatcatggag ttcgttgatt 2773081 ttccaaagat gattcccggt ccgcccgtcg ccataatgac agcgtctgaa cggaaggatt 2773141 caatttgcat gtttgtcagg ttttgtgcaa caattccgcg gcaggttctg tcatcatcta 2773201 aaacagcgcc aaggaattcc cagccttcgt attttgtgac cagacccgca acttcgtatc 2773261 tgcgcacttg ctcgtccagt gcgtaaagca gctgctgtcc cgtcgtcgca ccagcataag 2773321 cagttctgtg gtgctgtgta cccccgaatc ggcggaaatc aagcaggcct tcaggcgtcc 2773381 ggttaaacat gacgcccatc cggtctaata agtggatgat cgaaggcgcc gcttcacaca 2773441 tcgccttgac cggcggctgg ttggcaagaa agtctccccc gtataccgtg tcatcaaaat 2773501 gttcccacgg agagtcacct tccccttttg tattgaccgc tccgtttatg ccgccttgcg 2773561 cacaaactga atgagaacgt ttgacaggaa cgatggaaaa caatttaacc gccattcctg 2773621 attccgctgc tttaattgtc gccatgaggc cggcaagacc cccgccgact acgataatgc 2773681 ttgattgact catgatagcc cctctccctc tagtaatcta gtactcttaa acaaatgcaa 2773741 aaatcgcttt taagcctacg tatgacagtg caacaaaaat aatcagcgta acgtatgtcg 2773801 aaattctttg agaacgaggc gttaccgtga tgccccatgt aacagcgaaa gaccataaac 2773861 cgttcgagaa gtggaaaatt gttgataaaa caccgacaat gtaaaaacca agcatagccg 2773921 gagagctcaa aatattcgcc atcatgtcga aattgacctc agcacccatt tgtgcggcaa 2773981 tgcgggtttc ccacacgtgc cagctgacga aaatgagggt gatgataccg gttacacgct 2774041 gcaggacgaa tagccagttt ctcatgtagc tgtattgacc ggcgttattt ttcgcagtaa 2774101 acgctatgta cacaccataa actgcatgat aaattaatgg taagaagata ataaaaattt 2774161 ccaaggcata cctgaaaggc aggctatcca taaaatgagc agcgctattg aatgcttcag 2774221 cgccccttgc ggcaaactgg ttgacgacta aatgctgaat aagaaagatg ccgaccggta 2774281 tgacgccaag caaggaatgc aatcttcgaa aataaaactc tctgttccca gacattactt 2774341 taccccctgt ttgataagtg cgaaatgtgc taaatctctt cccccacttc tttcaattgt 2774401 aagcacttta ttaagattta ttgacaattt cattttactc ctccctcaaa agggcgtcaa 2774461 gaaaacgcgt acataaatta taattttccg aattgattag ttgattgaaa aattttattt 2774521 tatcaatata tatttcttgc ttaatttttc ataagaatta caggatcatt ctgtaatcct 2774581 cccccctgtt tgagctataa tatacgcagg agagagggga gacagatatg aagtctaaat 2774641 ttgaagcatc tattgacaac ctaaaagaaa ttgaaatgaa cgcttatgcc tacgaactaa 2774701 tacgagagat cgttctccca gatatgcttg gccaagatta ctcttccatg atgtattggg 2774761 caggaaaaca tctcgcccgt aagtttcctc ttgaatcatg ggaggaattt ccggccttct 2774821 ttgaagaagc gggctgggga accctcacca acgtaagcgc taaaaaacag gagcttgaat 2774881 ttgaacttga agggccgatc atttccaacc ggcttaagca tcagaaagaa ccttgctttc 2774941 agctggaggc tggttttatc gctgaacaaa ttcaattgat gaatgatcag attgccgaat 2775001 catatgaaca agtgaaaaag agagccgata aagtggttct gactgtgaaa tgggatatga 2775061 aagacccagt gtaatcaaaa aggcggtgac tgcatagtcc cgcctttttg attgtcatta 2775121 cacagctgaa gggtgttttg aaagctcaaa tgcatcgtga agcgactcga ctgctttcac 2775181 catgtcattt tcgcttacga ctgttgacac tttgatttca gatgtgctga ccattttgat 2775241 taaaatgttt ttttgcgcca gtacagcaaa catttcagcc gctacaccgg gatttgagac 2775301 catgccggat ccaacaatag atactttagc caatttgctt tctgtctcga ttttctcaaa 2775361 ttccagcgcg tctttatact cttcaagcac cgcaacggtt tggtctgcat cttctgtttt 2775421 gacagagaag gaaattccag tcttgtcctc ggcctgcgtt tggataatga tatccacgtt 2775481 tatgtttctt ttggcaagtg ttgtaaaaat agtagacaaa gttgtcaggc cgctagtcag 2775541 cccgtaaatg gttactcttg tgatttgatc ttcaaatgca atgcctctga caattaaatt 2775601 ctgttccatg gatgattcct cctcaattaa tgttcccgct tcggtttctg tacttgaacg 2775661 cacttctaac ggcacttggt aatttttcgc gaactcaact gctctcggat gaagaacacc 2775721 ggcgcctaaa ttggcaagct caagcatttc atcgtatgag atgccctcaa gttttctcgc 2775781 tgatttcaca tagcgcggat cggttgtaaa cacgcctggc acgtctgtgt atatgtcaca 2775841 tttatcagct tttaaagcgg cagccaaagc aactgctgtt gtatctgaac cgccccggcc 2775901 caatgtcgta atttcacaat cctctgtcat gccttggaat cctgcaacaa tgacaatttt 2775961 tcctttttca agctggtctg ctaaaaccga agtgtcgata tctgtaattc tggcgtttcc 2776021 gtgaatggcc tccgtacgga ttcccgcctg ccagccagta taagacacag cgtcatagcc 2776081 tttttcctgc aatgccattg aaaggagtga aatcgtgacc tgctcgcctg tcgccagcag 2776141 catatccatt tcgcgtttgc tcggctggtc agaaatagct tttgcaaggc tgaccaattc 2776201 gtcagtggat tttcccattg ctgaaacgac gacaacgact tgatggcctt tctgtttttc 2776261 tgcaattgcg cggtttgccg cattttgaat tttttcgact gagccgacgg aagtgcctcc 2776321 gaatttttgt acaataagac ccatgtatta ccacccttta cattttggtt cgtgcgggtg 2776381 aggagaaaga gcgctttgtc cacaataaaa aaagcaatga gaggaatact ctcattgctt 2776441 atcaattaat catcataaat gattatgaac aacgagatag ccctccaaga aaatgatttc 2776501 ttgacagcct tacatttatt caatgcacgg ccagcaaata ataccgatgg ggttttattt 2776561 gcttcggcga cgctcccctt tcagcctttt tcacagaatc catctttctc caaaggcata 2776621 ctcttgaagt tcgcacctct atcttcacca tataacacga tctaactatg aaattagttc 2776681 acattttatc agatcttatt taaaaggaca acattatttt tgcaatttgt cgtaaaggag 2776741 ctgagccgcc gctgcgggaa caccggcttt tttgatgtcc tcaaggcttg cttccttcat 2776801 ttttttaacg gaaccgaaat gctttaacag cattttcttt cttttctctc cgatacccgg 2776861 gatgtcgtcc aaaacggatt gaaacgcgct ttttccccgg atttgcctgt gaaaactgat 2776921 tgcaaaacgg tgcacctcgt cctgaatgcg ctgcaggagg taaaattcct ggctgtttcg 2776981 ttccagatac gccacctcca gcggatcacc gatcagtaaa tttgaggttc tgtgtttttc 2777041 atctttcgct aaaccggcga tcgggatatc caagccgagt tcattttcaa tgacatccct 2777101 tgctgcgttg atctgccctt ttcctccgtc aatgataatc agatcgggca gcggcagatt 2777161 ctcacgaagc actctcgtat agcgtcttct gacaacctct ctcatagaac cgtaatcatc 2777221 cggccctgta acagttttga ttttatattt gcggtattcc tttttgtatg gtttgccatc 2777281 gataaacaca atcatcgcgg aaaccgggtt tgtcccctgt atatttgagt tatcaaacgc 2777341 ttcaattctg tgcggcgtat aaatatttaa tgcctcacct agtttctgca ctgccccgat 2777401 tgaacgctcc tcgtcccgtt cgattaaaga gaatttttct ttcaatgcga ttttcgcatt 2777461 tttatgggca agcatgagca gttctttttt cgggcctttt ttcggctggt gaacgtttgt 2777521 ttccagtagc tgctcgatca tagattgatc tatgctgtcc ggaactaaaa tctccttcgg 2777581 aaggaagtgg ttgttttttg aatagaactg cccgatgaac gtgaggaact cttcatctgc 2777641 ttcctgataa agcgggaaca tgctgacatc gcgttcaatg agctttcctt ggcggatgaa 2777701 aaagacctgc acgcacatcc agcccttatc gtacgcgtac gcgaacacat cacggtcgac 2777761 tagatcgttc atcgtcattt tttgtttttc catcgttgat tcaatatggg caatttggtc 2777821 acgaagctct tttgctcgtt caaactcaag attctcagca gcttcatgca ttttctcttc 2777881 aagctctttt ttgacctcat tatagccgcc ccttaagaaa cgtgtaatgc tttcaaccag 2777941 ctctctgttc gtctcttcgg aaatatcctt tacacacgga gcaaggcatt ggcccagatg 2778001 atagtaaagg cacactctgt ccgggagctt ggagcatttt ctgagaggat acagacggtc 2778061 gagcagtttt tttgtttccc ttgctgcctg tacattcgga tacggcccga aatagcgccc 2778121 tttgtctttt ttgacattgc gggtgacaat cagccttggg tggcgttcat gggtgagttt 2778181 tatgaaagga taggttttgt cgtctttgag catgacgttg tatttcggat catgcttttt 2778241 gatcagattc atttctaaaa taagcgcttc aagattggag gacgtcacaa tatattcaaa 2778301 atcctcgatt tccgtcacaa gcctttgggt tttcgcgtcg tgagaaccgg tgaagtagga 2778361 gcgcactctg tttttcagca cttttgcttt ccctacgtag atcacagtct gctgccggtc 2778421 cttcatgaga taacaacccg gttgatcagg aaggagggcg agtttttctt tcagttgttt 2778481 gttcatatgt tacccttcct tatgtttaat cctttatttc cagtttaaca cgaacgtttg 2778541 tttttctcta tggttcacaa ttggcgaata aaaaaagcga tccctcaatc ggaatcgctc 2778601 tggcatgtaa gcagcggaaa attaaagatg tttgtttaca agctcttgaa gcgcttcttt 2778661 tggtttgaag ccgactgaag tttcaactac ttcgccgtct tttaacacaa gaagagtcgg 2778721 gatgctcata acgccgtatt ttccggcagt ttcttggttt tcgtctacat cgatttttac 2778781 gattttcagt ttgtctccca tttcttgatc caattcttca agaacaggtg caatcatttt 2778841 acaaggtccg caccaaggag cccagaagtc tgccagtacg acgccttcgc ttgtttcagc 2778901 tgagaaagat tgatcagttg cttttacgat agccattatt gaattcctcc aatgtgaaat 2778961 gatgattttt agtatagcat ctcccattcg ttcacgctat tttaatgctt acaaattatt 2779021 ttttcctgat cacagccggt ttactcattt ttatatggtt gaatgggata tgctcttttt 2779081 ttaaaacaca aatctgataa tggccccgat cactacaatt gccccaataa tcattaaaat 2779141 ggtacgaagc ataagatcac atctcctctt cactgtcatg tactttacca tgccctgccg 2779201 gagctgtttt aaaacctgaa aaagagcgcc ggcatgaagc tccggcgctc ttgcgcgatt 2779261 aagaatcagc acgcagcgta agtaagacga ctgacattgg cgggagtttt actttcagtt 2779321 tgtttttgct gagcgtgtat tgtctgaagg attccggttt gacatgatga ggatcgtcaa 2779381 acgtgttatg cgcattcatt ttttctgccg taagaatgac tccggaatgg tccgctgcct 2779441 tgtgtaggcc cctcagctcg atttccgcct ctgctttgtt ttggtgatcg atgttgcaaa 2779501 ttgtgatatt gatatcgcct tcagcttgtt tcgacgctga aatgctgatt tgcggaagcg 2779561 tttcaccgtt ccattcatag tcggcagaca ttgtctctgt ggctaaaaga gaagcgtcct 2779621 ggtgcacctt aaacatattg aatacatggt acgtcggtgt caaaagcatc cgctctccct 2779681 cagtcaaaat catcgcttga agaacattta ctgtttgggc gatgttggcc atttgcaccc 2779741 ggcggcaatg ctgatggaaa atgtggaaat gagaagccgc caccagtgca tcacgaatgg 2779801 tgttttgctg atataagaaa ccgggattcg tgcctggctc gggatcaaac cacgtgcccc 2779861 attcatcaat aatcagcccg acccgctgct ccggatcgta ccggtccata atcgtgccgt 2779921 gtttttgaat caattcatcg atgtatttgg cttttttcat cgtaataaac cattcatctt 2779981 ccgtgaattc tgtggctgat cctttgccct tccagaaatc ccccggaatc gtgtaataat 2780041 gaagactcaa cccgtccatc aggccagcgg cttttttcat aagcacgtcc gtccaattaa 2780101 aatcatccac atttgcgccg cctgcaattt tataaatgtc attcccgctg taattgcgga 2780161 cataagtctg aaaacgccgg tacagatctg cgtagtattc gggatgcatg ttgccgccgc 2780221 agccccagtt ttcattgccc acgccgaaat atttcagctt ccaaggctct tctcttccat 2780281 tttgctttct ccagtctgac atcggcgtgc cttcttcaaa tgtcatatac tcaatccact 2780341 ccgacatttc ctgaacggtt ccgcttccga cattgccgca aatatatggc tcgcattcaa 2780401 gcagctcgca aagcatcata aattcatgcg ttccgaattc atttgattca attgtaccgc 2780461 cccagtgagt gttcagcatt gtcttacggt caccgacacc gtttgcccaa tggtattcgt 2780521 ccgcaaaaca cccgcccggc cacctaagga caggaatgtg cagctgtttg agcgcctcca 2780581 gcacgtcctt tcgtatcccg ttgatattgg ggatgtctga gtccgttccg acccagatcc 2780641 cctcataaat ccctcttcct aaatgctcag caaaatgacc gtatatattt ttgttaatgg 2780701 ttccttttgc gatatctgtt tgaatcactg cttgatgttc agacatgcct ctgatcattc 2780761 ctttcatacg gatatgaaaa gcaccacagt caaatatgtg atctgtcgtt tgcctgagga 2780821 gtcagcatga atgtaagcgc ttttaaagta accatattat atatgttcgt acatgtcaac 2780881 gacattttct attgttttta tatttgtacg tatgtattta taaatatgaa aaaacccgga 2780941 cttttaaagt ccgggatttc ctttatgagt gtatattcag ctgtttgaat tcctcagtta 2781001 ataacgggac aacttcaaat aaatcaccga cgatgccgta atccgctatt ttaaagatat 2781061 cggcttcggg gtctttattg atggcgacga tcaccttgct gtttgacatg ccggccaaat 2781121 gctggatggc gccggaaatg ccgcatgcaa tgtacaaatc cggagtaacg actttcccgg 2781181 tctgcccgat ttggagagca taatcgcaat aatcagcgtc acatgccccg cgagaagccc 2781241 cgactgcggc ccctagcacc tctgcaagct cctgcagcgg ctgaaatcct tccttgcttt 2781301 tgactcctcg gccgcccgca acgataattt tcgcttcgga gagatcaaca ccgtccgccg 2781361 tttttttcac gacctcttgg ataacagtgc ggaggtcagt aagagaaaca tcaatgcttt 2781421 cgatgctccc cgatctgctg gtgtcttttt ctgaagcttg aatgttattg gggcgaattg 2781481 ttgcaaagat catcggatcg gttgaaatga cgcgttcaaa agctttcccc gagtaaatcg 2781541 gccgtgtgaa cacaacattc cctccggtaa cgcttacatc tatagcatca gaaattaagc 2781601 ctgtttgcag acgggcagca agcttcggtg aaagatcctt gcccattgcc gtatgcccga 2781661 agatgactga atcaggattt tcttgctcga taacacctct catgacctgg ctgtacccgt 2781721 ctgccgtgta tgttttcagc ttcgggtcct cagcggtaag aactttatct gctccgtaat 2781781 gaataagctc ttgtgcaatg ctttgtacat tttcaccgat gagaacaccg atgacttccc 2781841 catctcctga aatggttctt cctgcagcta ttgcttcaaa ggtgacattt cgcaattccc 2781901 catcgcgtat ttctccaagc acgatcactt tttttcccat tctaacatcc ccctgtttct 2781961 ttgaatgtcc aagttttaaa tgactttagc ttcgctgcgg agcaatgaaa caagctcttt 2782021 tgcctgttca gcaggctcac cttggagaag cttcccggct tcttttttcg gcggcagaaa 2782081 acgttcaatg gttttcagct ttggttcagc atcctcttcg tccagatcaa gatcatcaag 2782141 ttcaagctct tcaagcggct ttttcttagc cttcataatt cccggaagcg atggatagcg 2782201 cggctcgttt aagccctgct gagctgtgac aagcaatggg agcgtcgttt tgattttttc 2782261 aacatcccct tcgacgtccc tttctgcttc tgcatcagtg ccgttgattt cgagtttggt 2782321 gatcgtagtg atacacggaa tgtccagtag ctcggcaagc cgaggcgcca cttgtcctga 2782381 tcctccgtca atggcaacat ttccgccgag aatcaaatca aactcctgat ccttcatata 2782441 gtggtataaa acttgagaaa tggaatattg gtcgggttca tcaagatcat cttctatgtt 2782501 gattaaaaca gcttggtcac aacccatggc aagcgccgta cgcaattctt tctccgcttc 2782561 ttcaccgccg accgtgacag cggtgatcgt gccgccatgc ttttccttca gctggatggc 2782621 ttcttctatc gcgtactcat catatggatt aatgatccat tccgctccgt catcctgaat 2782681 ctttcctgtt tcaatgacga ttttttcttc tgtgtcaaac gtccgtttca tcagtacaaa 2782741 tagattcatg atcatatccc cttttattcg cctttgaact gaggctttct tttttcgaga 2782801 aatgcctgga tgccttcctt ggcgtcctct gactcaaatg cttccccaaa tcgctttgct 2782861 tcaagcttta agctgccttc ataggaatac accttgttgg aataaagaag ttcaagcaaa 2782921 gatgccagcg tttgcgggct tttctctgca aacttagcgg caagtgcttt tgctttttca 2782981 atcacttctg cctcatcttt cgctccaatt gagacaagtc cgagatcaag cgcttctttt 2783041 ccggatatcg gttctcctga tccgatgagc tccagtgctt tggctgtacc gacatatctc 2783101 ggaaggcgct gtgtccccgc aaaacctgga atgataccga gattaagctc cgggagcccc 2783161 agcttagcat cttctgccgc gattctgatg tgacaggcca ttgcaagctc cagcccgcct 2783221 ccgagagcag cgccgtgaat cgctgcgata atcggttttg gaaaactttc gattctctcc 2783281 attaactgct ggccgcgctc agcgagcaat gaggaatcct cattgccttt aagcgatgta 2783341 aattctttaa tatcagcgcc ggctgagaaa aatcttccct cgccgtgaat gataatgctt 2783401 cgtacgcctg catctgtctc acattgatca agacaggaag acagctcttc taatatccgg 2783461 cttgaaagcg cgtttgccgg cggattgtga atcgtcaaga ctgccacaaa ttgatcaacc 2783521 gcaagtgaaa ttgcattcat aggacagaac tcctttactt attgtgaatt ccggatacca 2783581 ataattctaa aacgctgttt gaaagcgcaa cgagatcgta cttttggtca ttcatcaccc 2783641 aagttgtcac agtttcgtca atcgttccaa aaatcatctg ccgggcgagg cggacatcga 2783701 ggccttcttt tatttcgcct gattgtatac cttccgtcaa aatgccatcc aaaatattta 2783761 agtagccttt taatatttcg ttgatttttt ggcgcagctc caagttggat tggcggagct 2783821 caagctgcgt gacaatggcg agattatggt cacccgctaa aagggaaaaa tgctttgaaa 2783881 tcacaagcgc caatttctct ttcgctgttg ctttttcttt aatgtcctct tccatccgct 2783941 caataaattg acccattttt tctttgaaaa gagaaattaa aatatcttct ttgtttttaa 2784001 aatagagata gatggtgccg tccgctaccc cggcttgttt ggcaattttg gatacctgtg 2784061 actggtggta gccgttttct gcaatgactt ctactgctgc atcaataatc tgcatatact 2784121 ttggccgttt ttgcttcaat gttcatcgtt ccttcctata gaaatgaatg actattcatt 2784181 cataatttca tgataagaag gattttcagg tttgtcaagt ttattcatag gcgttctctt 2784241 tttttatttg atatgatgat tttcggtttc ttcttcaagt aaacgccttc ttaaaatttt 2784301 tcccaccgcc gttttcggca gctcctttct gaactcatag gctttgggca ccttataggg 2784361 agctagacgt gatctcgcaa aagcgtccag ttcttctgta tcggcttttg cgcctttctt 2784421 taatacgaca aatgctttta ctgtttctcc cctgtaggaa tcgggaacgc ctgcgacaac 2784481 aatttcctgg atggcttcat gttcataaag cgcttcttct acctcacgcg ggtaaatatt 2784541 gtaaccgccg gcaatgatga tatccttctt cctgtcagca atatagaaaa agccttcttc 2784601 atccatatag cccatgtccc cggtgaacag ccagccatct ctcagcactg cggcggtttc 2784661 ctctggttta ttccagtatc ctttcatgac ttgcggacct tttacaatga tttctccatg 2784721 ctcatacgga gcggcaagct cacccgtctc ttcagaatag atcgcagcgt ccgtactcgg 2784781 ccaaggacag ccgatactgc ccggcttgtt ttttccccag ataaagttgg cgtgcgtcac 2784841 tggggatgcc tcagacaaac catagccttc cacaagcttt ccaccagtca ccttttcaaa 2784901 tttctgcttt acctccacgg ggagcgcggc tgatccgcta agacagcttt taatggatga 2784961 cagatcataa tgctgcaatt cagggtgatg caaaaggcca atgtaaattg tcggtgcgcc 2785021 aggaaagagc gtcggtttgt gtttgtcgat gattttaagt gtttcgagcg gatcaaactt 2785081 aggaagaaga atcatttcga agcctagttt aatcgaatag ttcatgactg ccgtcagtcc 2785141 gtagacatga aaaaatggaa cgatgcccag cactttttca gcgccttctt tcacgtcata 2785201 catccaagcg gcgcacattt cagtatttgc caaaatattt tggtgcgtga gcatgacccc 2785261 ttttggagct ccggttgttc ctccggtata ctggaggaca gcgatatcat gctcaggatc 2785321 gatcttcggg attgtcagga gttcagtttt ttcctgcttc atacaggaag cgaacgtgtg 2785381 aatgttagct gttttgtcaa agtcgatatg cactttttgt ttttgcgtca gcgggtaaag 2785441 aatatttttc ggaaaaggca aatagtcttt tacactggtt atcaaaatct ggtcgactat 2785501 tgataacgtt ttcattttta ttgccttcgg gaaaagcaaa tctaaggtga tgattacact 2785561 tacctgagca tctctaagct ggtattcaag ctcatgctcg gtataaagcg gattcgtctg 2785621 caccacgatg ccaccggcaa acaagacgcc ataataagaa atcactgttt gcgggcaatt 2785681 gggcagcata acagccactc tgtctccttt ttgcaggcca ttgcactgca aaaaagctgc 2785741 aagtttaaga gcatccgtca gaatgtcatg aaaggtgagt ttttttccat aaaacgatat 2785801 tgcggtttta tcagggaatc gtgcggcgga gtctgtcagg atggattgca gggttttatt 2785861 cggcaacgga agctcatgcg ggatatcgtt gggatactcg gcaagccacg gcttttgaga 2785921 ctgcataaaa cctccccttt cgattttaga gatccacctt atcattatag cagatggacg 2785981 gcaaaaaaaa gaaaaagaaa ggtaaatctt tctttttctc ataatatgaa cagatatata 2786041 agaccaatta acaaaaagat tcccgctgcg gcgagcagta ttttcgcaag cttttccatc 2786101 tattctccgt ccccttatat tccggctgcc accacaaaag aaagcccgac agaaatgaca 2786161 aatgaaataa agccgacagc ccggttatca ttttcgattt cctgatcaat tttaaaccgc 2786221 ggagtcaaaa actcaaaaat aaagtagctg atcagaagca taacaaaccc gtaaacgccc 2786281 cagccgatca tttgcagcag cgaattatgc tgggagatgg aatgctgaaa tacgtttgcg 2786341 attcccaaaa tttttccgcc ggtcgccatt gccaccgcaa gatttccttt ttgaatctct 2786401 tcccagtttt tataagccgt caccagctca aacacagtca aaaagaggac gaggcagaga 2786461 accgcgacac tgtaatatgc cgcgatttcc acaagctcgt tttcccaaaa atcactcatg 2786521 gccatactcc cttttatttt agttcaacaa ccgtaacgcc tgatcctccc tcacctgctt 2786581 caccgaaacg ggaacttttg acgctgcggt ggtttttcag aagatcctgt acgccttttc 2786641 ttaaagcgcc ggttcctttt ccgtggatga ttgacactct tggatatccg gctaacaccg 2786701 catcatccaa gtatttttca acccggctga gggcattttc atagcgttcg ccgcgaagat 2786761 caagttcaag cgatacgtga tagtcctttc ctttgaccgc tgtaatcatt ttttcttttt 2786821 ttggctccgg agctgatttg ataaactcca gatctttttc ttttactttc atctttaaaa 2786881 taccgatttg aacgttccat tcattgccgc ctgttttttc gagcaatgtt cctttttgcc 2786941 cgaaagtgag gactttcacc tcgtcgccag gcttaaagtc gcgtttttgc gttttcggct 2787001 tttccggttt cttggacttt tcaaaagcag gcatagcgcc ttctaaccgt ttcttcgcgt 2787061 taatcagctc gtgatccttg aaggatttgt gttcttcttt tatggtgcgc aattcatgaa 2787121 taatgtcctc ggcttctttc attgccgctt ttactttttc agcagcctgc tgttctgcct 2787181 cttcaagcat tttgtctttt ttgctgttaa gctcgatgat ttgctgctgc agctctttat 2787241 gcagtttttc cgcttctttt ctgattgatt ctgtctcaga aagctcttct tccgcacgtt 2787301 ttttgctttg ttccagcgac gcaatcatcg tatcgacttc gttatgctcg gccgtcattt 2787361 ctgacttcgc ctgcccgatg atatggtccg ggagcccgag gcgttttgaa atttcgaaag 2787421 cattgcttcg acccggcaca ccaattaaaa gtttataggt cggtgacagc gtttcgatgt 2787481 caaattcaac gctggcattc atgacgcctt ctctgttata gccgtacgcc ttcaattccg 2787541 gataatgcgt cgtagctaac actcgtgcat tggtgcgatg cacgtcatcc aagatgctca 2787601 tggcgagggc cgccccctcc tgcggatctg tccctgcacc aagttcatcg aaaagcacaa 2787661 ggctgttttc attgacctgt tctaaaatgc cgacaatatt caccatatgg gatgagaacg 2787721 tacttaaact ttgctcaatc gactgttcat caccgatatc agcgaatacg tgctcaaata 2787781 ctgccgcttc tgacccttca tctgccggga tatgaagacc tgactgcgcc attaaggtta 2787841 gcaggcctaa cgttttaagg gtgactgttt tccccccggt gtttggccct gtgatgacaa 2787901 tggttgaaaa atcgcggcca agctcgatgt cattggcaac aacctgatca ggcggaagca 2787961 atggatggcg ggcttttttc aaacggataa agccggtgtc gttcataatc ggttttgtcg 2788021 ctttaaccgc ttttgcatat ctagcttttg caaaaataaa gtcaagcgtc tgcagcactt 2788081 gcaaatctag aaatagctcc tctgtatact ctgccgtttt ctctgtcagc acacgcaaaa 2788141 tccgttcaat ttcttgcttt tctttcactt tcgcctgctg aagggaattg ttcatatcta 2788201 caatcgcctg cggttcaatg aatagtgtcg caccagagga tgaggtgtcg tgcacaattc 2788261 ctccatagct ggatctgtac tcctgtttga ccgggatcac aaagcggtca ttccgaatcg 2788321 taacaatcgt atcagacagc attttcgatg cggaagagga acgcagcatc gactctaacc 2788381 ggtctctgac tcttgattcg agtgttctga gctgtgtgcg gattcctctt aatgtttccg 2788441 atgcatgatc aagcacttct ccgtgatcat caatgcagga attaatgtcc cgctctaaat 2788501 cggacagcgt gataagctgt tcagcatgct gatggatcag cggaatgtcg acaccgtctt 2788561 cagccatttg cgtgataaaa tgtttcattt gtttaactgc ataaagcagg cctgagattt 2788621 cagtgaattc agaaggactg agaacgctgc cgatttccgc ccgtcttaac gctcctctga 2788681 tatctacaag gccgccaaat ggcgcttggc ctctcagccg gataatgtca gaagcttcgt 2788741 ctacttcatc cagctgtttt ttgatttcgt ctatagaagc agaaggctta agctcgagaa 2788801 gcatttcttt tccgagcgat gaagcggcat gcccaataac ctgttctttc actttatgaa 2788861 attcaagagc tgataatact ttttgctgca cgattgtgtg agcctcctta cttaatcgtt 2788921 gcgcttcaga aatgcctcta cgtctttaag cgaccgggca ttcagaacgt ttttcgtttc 2788981 cgtccatcct ttgcgcgcgg cagtaacgcc agttttcata tcgtctaaca tctcaatatt 2789041 atgggcatca gtattaatca ccaatgtaac cccttgttcg tttgctttca ttaaatgctc 2789101 tgtgcgcaga tcaaggcgcg cagggttggc attgagttca agcgccgtat ttgttttcct 2789161 cgcaagctca atcagctgat caatatcgat ttcgtaaccg gcccgtctgc cgataaggcg 2789221 cccggtcggg tgtgcgataa tgtcaacatg cttgtttgtc agtgccgtct caagccgttt 2789281 cataatcacg tgttccggct gattaaaact ggaatgaatc gatgcaataa cgatatccat 2789341 ttccgcaagc acatcgtcat cataatcgag cgtaccgtca ggcaggatat ccatctcaac 2789401 gcctttcaaa atacggaagt tttcaaactc tgcattcagc gcgtcaattt cttttgcctg 2789461 ctgcttaagt ctttctgcag taagcccgtt ggcgaccttt aaatattgtg agtgatcggt 2789521 gatcgccatg tattgatagc cttttttgat gcaggcttca gccatctctc tgatcgaaaa 2789581 tgcgccatcg ctccacgttg agtgcatgtg gagatcacct ttgatttgcc cgagctctat 2789641 cagttcaatg ctgtcgctgt aggtttccac ttcctgtccg ctttcacgaa tttccggcgg 2789701 aatcagcggc aggccgaagt gcgcataaaa ttcacgttca ctcggaaatg ttttgatctc 2789761 tccggtttca actgtctcaa cgccgtattc actgatccgc tcgccgcgtt ctttggcgat 2789821 ttggcgcatc ttaatattgt gatcctttga tcccgtaaaa tgatggagtg ttgtcggaaa 2789881 ctgctcttcc gtcacaagac ggaaatcgac gcttgtttca tattcaaagg aaaggatgac 2789941 ggacaccttc gtatctccgc ttgcgatcac gcttttgatg tttggcagct caagaagctg 2790001 ctctcttact tcagccggat gatctgtagc aatgatataa tccagatcct tcaccgtttc 2790061 ccgcgctctg cggagacttc cggcacgaga aaatttgatg atatgcgtaa attgagaaag 2790121 atgctcctca atttcccgcg cgatccggag ggcgtagccg atcgggaacc gttcaggctg 2790181 ttttccggct tccccgagcg cctgtaatat tttttcttcc gattttttgc cgaagcccgc 2790241 aagaccctgg accttttgct gctcacaggc ttccttcaga gattctgcat cgtgtacgcc 2790301 gagctcttta tacagctttg cgattttttt gccgccgagc cccggcagct tcaataaagg 2790361 cacgagtcct tccggcactt ctttctgaag cgattcgagc gtgcttgact ttccttcatc 2790421 tatatactct ttaatgacgc tgtacgttcc ttttccaatg ccggacagcg acatcatatc 2790481 gtccatttct gataagcttc ggtcgtcctg ttccagagct gccgccgctt ttcggaaggc 2790541 ggatacttta aacgggttgt cccctttgag ttccatatag actgcaatgg tttcaagcag 2790601 ccggataata tcttttttat gcatatcata acccccagac gttcacatat gtttccatca 2790661 tacttgaaaa aaacttctcc ggacaagaga agttttttta tgccccgtac tgtgtccaca 2790721 gctcttgtaa aagccctgac aagtacggtg tatggttaat gatcacattt gcgagagacg 2790781 attgccccat catttgctgc aacgcgtcta ccggcagaac ggatgcgaca tacagcagca 2790841 caaatgtaaa taaatagact tctagaaaac cgagaacggc tcccagcatc tggttgattt 2790901 gtttaatcac cggaatgccg gctacaatac tcaggaacga gccgatgatt ctcagtaaga 2790961 ttttagcaat gataaataaa acgataaacg caatcgcatt atagtacgct gcttccaaat 2791021 tccccgtaaa aaaagaaaga gccggctgtc ccgctgaaaa atcgggtgcg ggaatccaat 2791081 gtaaatgcgg tgccacgttt ttatagaata aagccgcaaa ggcaattgat aaaataaagc 2791141 tcgtcaagcg gataaactgc aggataaaac cgcgttttaa ccccagtaaa gtccccatca 2791201 ggagcaagat taagatgatg atatctagca tagttgttca atccttttct ttaagctgac 2791261 gctccagttt ttcacatttc tcttgtaatt tgacataatc gtgcaccaca tttaccgctg 2791321 tcagcactgc aagtttattt atatcaaggt atggattttt ttcattgatt tctctcattt 2791381 tatcatcaac aattccggcg acatacctca tatgggctct gctttcttca ccgacaatcg 2791441 tgaagtgctg gccgtaaatg tcaacggttg tttttgtttt tttgccgtca gacaacgttt 2791501 ctcctccatt ccgcgagaat cctagttctt atcataacac gtttattaaa tgaatggaaa 2791561 gacgagcctc ccgctgttat gatacactgg tatatacagc gaaaagtgta aaaaaaggag 2791621 attattacgt gtcccattca gtgataaaag tatcgttgtc tgctattgac caaatgaaaa 2791681 tgacgtacag cggttcactt acagcctctg ttccgcaggg agccgttttt caggcaaaac 2791741 cgcccggctg taccattaca gcatatcaat caggtaaggt cttgtttcaa ggaaaaaacg 2791801 ctgcggcaga atccgcgcgc tggggaacag cagagcctca ggaaaagaag aaaacggcca 2791861 aaaagccggc tgatccccgc tatgcccctc cggcagatat cgccggaatg tctgttatcg 2791921 gttctgacga agtcggaacc ggagattact ttggcccaat gacggttgta tgcgcgtacg 2791981 tcgacaaaac catgcttcct ttaatgaagg aactcggtgt taaggattct aaagatttaa 2792041 aagatccgca aatcatcgag attgcccgaa acctgattaa aaccattccg tacagcctgc 2792101 tggtgttaaa gaatgaaaag tataacagca tgcaggaaaa aggcatgagc caagggaaaa 2792161 tgaaagcttt gctgcacaat caggcgatca cacatttatt aagaaaattg gatggagtaa 2792221 agcctgaagc cattttgatt gaccaattcg ctgagccagg cgtctacttc aatcatttaa 2792281 agggcagaga cattgtgaag gagcggacct attttagcac aaaagctgaa ggtattcacc 2792341 tggctgtcgc cgctgcttca atcattgcaa gatattcatt tttaatggaa atggataaac 2792401 tatcacgcgc ggcaggaatg acgcttccaa aaggggccgg tccgcacgtc gatgaagcgg 2792461 ccgccaagct gatcctcaaa aaaggggcat ctgcactcag aacctttaca aaactccatt 2792521 tcgccaatac gcaaaaagcg cagcgccttg ctgataaaaa acgttcatag aaaaaagctt 2792581 gcagatttct ctgcaagctt ttttatcagc ctcttaaaac agcttgatat gtgtcttcta 2792641 acgctttcag cactttgctg tgcgcctttg tcacttcttc ttcagtcagt gtttgttcag 2792701 gattgacata ctggagtgag aaagcgactg acttcttgcc ttcctccata tgctctcctt 2792761 cgtatacgtc aaatacggtt acctctttca gaagcttgcc cccggcctct ttaatgacgc 2792821 tctcgagctg tccgcttgtg acggttttat ctgttacaag agcgatatca cgtgtcacag 2792881 acggatattt tggaatcgcc gtgtaaacaa gcggtgctgt ttctgctgcg agcaacgcat 2792941 gaagatcgag ctcaaatacg tatgtttcct ttatatccag ttctttttcc aatgaaggat 2793001 ggacttggcc gatgaagccg atcagagaac cattcaataa aatgttcgct gttctgcccg 2793061 gatgcagctg tttgcgttca gactgtacaa attcaatgct gtctaggacg ttgagtttgt 2793121 ctaacagccc ttccacaatt cctttgacaa caaagaaatc aactggtttc ttttcaccct 2793181 gccatagctg cttgcgccat aatccggtaa cagctcctgc tacgcgttct gtttcaacag 2793241 gttttgtgtc ctcttccttc gttaggaaaa cggagccaac ttcgtacagt gcaactgagt 2793301 cagtctgcct cgcaagattg taagaaacag aatcaagcag atttggaaca agactgtgtc 2793361 tgagaatgct tctttcttca ctcattggaa gcgcaagcac agtattcagt gatttttcaa 2793421 tcgcaaacgc tgtcgctttc ttctcgtttg tcagtgagta agtgatggct tgtgataagc 2793481 ctgcgccttc aaggaagcgt ctgactttac ggcgttttgc ctgatatggc gttaatccgc 2793541 ctgtagttcc cgctgtctca ggaagcgtag acggaatgtt atcgtagccg tacagtcttg 2793601 ccgcttcttc gattaaatcc tcttctattg taatgtcacc gcgccgtgat gggacagtca 2793661 caacgagaag atcatccgct tcaccgaccg taaaaccgag acgtttataa atgctgatca 2793721 gttcttcttt actgatcgtc aggcctagaa cgctgctcac tttgtcagca gatacgtgaa 2793781 tgttatttgc ttcgattgtc aggtgatctt cctcaaccgt tccagcaagc acctcaccgc 2793841 cggcatacag atggatcagc tgcgcagccc gttctgctgc aagacgtacg cgtgccggat 2793901 caattccttt ttcaaatctt acgcttgatt cacttctcaa accaaggtct ttggaagcct 2793961 tgcgaacctt ctgcccgttg aaatacgcag cctcaagcaa aatggttttc gtatcttcct 2794021 gaacctctga ctctgctcct cccatgacac cggcaacggc ctgcgctttc gttccgtttg 2794081 taatgacaag gtgatcggca gacagcttac gttcttgatc atcaagtgtt acgatcattt 2794141 cattctcagc tgcttttctt actacgactt ccttagagcc aaatctgtca taatcaaacg 2794201 catgaagcgg ctgtccgtat tccaacagga caaaatttgt gatgtcaacg acgttgttgt 2794261 gcggacgaat gcctgcattc atcagctttg tctgcatcca aagcggtgac ggagcaatcg 2794321 tgacattttt aatgattttt gcagtgtaca gcgggttcgc ttcttgatct tcaattttga 2794381 ctgaaatgta atcagacgct tgttctgaag cagccgggta atccgtttgc ggaagcttta 2794441 cctcagtgtc taaaatcgcc gcaacctcgt aagcaacacc aagcatgttc atggcatccg 2794501 cgcggtttgg cgttaaaccc agctcaagaa tcgcatcgtc aagctgtaaa gccgctaagg 2794561 catcgcttcc tgtttcagcg tcattcggga atacgaaaat gccttctgca tactccttcg 2794621 ccacaagttt gctttcgata ccaagctcct gtaaggaaca gatcatgccg tttgattctt 2794681 caccgcgaag cttggctttt ttgattttga aattgcccgg cagcaccgct ccgactgttg 2794741 caactgcgac tttttgtccc ttatccacat tcggcgcgcc gcaaatgatt tgtacagggg 2794801 cttcagctcc gatatccaca aggcacttat tcagcttatc agcattcggg tgctgctcgc 2794861 gctccagcac atggccgatg acaacgcctt tgatgccttc tcctttgtat tcaattcctt 2794921 caacctcaat accggctctt gtaatttttt cagcaagaac agccgggtcc atgcctttta 2794981 aatcaacata atcctctaac catttataag aaacaaacat ccttgcatcc tcctcttacg 2795041 cctgtttaaa ctgcgaaata aatctgacat cgtttgtata gaagtggcgg atatcatcaa 2795101 tgccatattt cagcatcgcg atgcgctcaa cacccattcc gaatgcgaag ccctgatatt 2795161 ccttcggatc aaagccagcc attttaagca cgttcgggtg aaccattccg gcaccgagga 2795221 tttcaatcca gcctgttcct ttacatactg agcagccgtt cccaccgcat ttaaagcatg 2795281 tcacatccac ttctactgaa ggctcagtaa acgggaagaa gcttgggcgg agtctgattt 2795341 cacggtcttg cccgaacatt tttttcgcaa caagttcaag cgttcctttt aaatcactca 2795401 tgctgatgtt tttgtcaacg acaagccctt caatttgcat aaattggtga gagtgcgtcg 2795461 catcatcgtt atcacggcga tatactttac ccgggcaaat gattttaacg ggacctttgc 2795521 cttcatgctt ttccatcgta cgtgtttgga caggagaagt ttgcgttctc atcaaagttt 2795581 cctctgtgat gtaaaagctg tcctgcatat cgcgcgctgg gtgttctttc ggaagattga 2795641 gcgattcgaa gttgtagtaa tccgtttcaa cctctggccc ttcctcgact gtgtagccca 2795701 taccgataaa taaatcttca atttcttcaa tgacaacagt gagcggatgg cggccgccga 2795761 ctgcaacagg gttccccggc agcgtgacgt caattgtctg tcctgcaagc ttctgtttca 2795821 tttcctcttc ttcaagcttc tcgtttttgt cagcaatcgc attggcaata cgctccctta 2795881 cttcgttcgc gagcgccccc atttttggac gttcctcagc agaaagcttg cccattccgc 2795941 gcagcacttc tgtaatcggc cctttttttc cgagatattg cacccgaata tcattgacaa 2796001 ccttcaatga gcttgccgct tctacttgtt ctaaagcttc ttgttccagc tgttttagct 2796061 tttcttccat tttgcatcct ccttttatgt aaacaaaccg tcatatgtct ttggaaaata 2796121 aaaaaaaccc gtcccttgta caagggacga gttgtggccg cggtaccacc cttatttcag 2796181 acagactgat gctgtcgtca gcttcattga cataacggaa tcagattccg gttcaccttt 2796241 acgcgcagtg tacgcggtcc cggcgacaac tcaagaggtg aagccaattt ccggctgcgt 2796301 taaaaatgct ctcagtcagc ggcattttct ccctggaaag cagttgatca gaaattgagg 2796361 tcctctgtca cggtttttga aatattatgt tctattatag agaaatccaa cgcttggcgc 2796421 aacactatcc tcgcaagtga tacacgagga tggcagccgc aaccgcaacg tttagtgatt 2796481 cagcctgtcc gtaaagcggc acgtacaggt tcaaatccgt tttttccagc aatgcagcat 2796541 ctacccctgc accttcattt cctacaatga gcgcaaagga ttcagactga ggaatctcct 2796601 ggtaaggcgc tccgttttgc agcgccgtgc cgtatacttt tacgccctct gccttcaatt 2796661 cgtccacata tgaaggcagg tttcttctca caacaggaat atggaagtga gatccttgag 2796721 cagatcgcag tgtttttccg ttaaaggcgt ccgccgtgcc gtcaccgagt acaaccgcat 2796781 ccaaaccggc cgcatcagcc gttcgaatca ttgtgccaag gtttcccgga tcttgaacag 2796841 cgtcaatcag cagcaccttg cgtgccgttg ccagcttttc ttcaggcata tggcacacag 2796901 cggcaatctg ctgcggcgtt tcggtttcag tcacagctga aaacgcatct tcactcagca 2796961 tatagcactg gataccagtc tcaagatctg aaggaatcct cgtttcatcc tttacaagga 2797021 tttctttcac aatgcccggg cttttcaacg cctcttcaac gaggtgttct ccctctatca 2797081 gaaatgtatt tgtttttgtt cgttcttttt ttgtgtgaag ctttttccaa tccttcactt 2797141 tttggttttt tgccgattct atttgtttca ctgtctatgt ggcgctcctt tttttaacat 2797201 gatgttatta tatcgcaaga acagcacata ataaaccagg tgcagggtta gaatatacgt 2797261 attacatttt agaaaaagga gcgttttaca tggatcttaa tttacgtcat gccgtcattg 2797321 ccaatgtcac cggcaataat caggagcagc ttgagcatac aatcgtagat gcgattcaaa 2797381 gcggtgaaga aaaaatgctt ccagggctcg gcgttttatt cgaagtcatt tggcagcacg 2797441 catccgaaag tgagaaaaac gaaatgctga aaacgcttga aggcggatta aaacccgccg 2797501 aataagacat gaaaccgggt gacagcgccc ggtttttttc ttatataata aaaacatgat 2797561 gagggggaac gccatgtttt tacagccgtt attagcgaaa aaaattattg ctgaagttaa 2797621 aaaaatgtac gaacgtgaag tcattattgt aaacacggac ggtcttatta tggcaggcac 2797681 aaacgatgag cgtgtcggac aatttcatga gggagcgctt atctgcgcaa aagaaagacg 2797741 cagcgtgatt attacaaaag aagatgaaac aaggttaaaa ggagtgaaag caggcataaa 2797801 cctccctgta ttttttgacc atgatgtgat tgccgtcttc gggctgacag gtgagcctgc 2797861 agagattcag ccattcggag aactgcttcg aaaaatgaca gaactgttca ttaaggaatc 2797921 gcggcactta gagcaatccc agtggcgtga gagaatgctg gagtccttta tgatcgattg 2797981 gctgcaatta aaggagtggt ctcccagttt tcttgagaaa gctcagcttc ttggtgttga 2798041 cctttcttcc cggcgccaaa tgattcttat tcaggggtat gagtggtcac ctcatgatat 2798101 tgaacaaatg gcacgcagct ggaaatcctc gtaccctgcg gatttgttca tcaggtgggg 2798161 aaatgaacgg attttgatta atcatgaagt gccgcagcat gaacaaaggg atcggctttt 2798221 gcggaaaatc cttcacattt gttcgtttgc caataccgca agcagccaat atacagcagc 2798281 tggcgccgga agggctgtcg caagctccag cctgacagat tcatacgagc aagcggaaaa 2798341 agcgctggct gtcagcctta agcgaaaaac gcccatattt gaagaggatc tgaagcttga 2798401 tatgtgtctg acggagatca gcccgggaac ccgaaacgaa tttccgcaaa gagtattagg 2798461 aaaggcgcta gagcatcagg aacttatgaa tacgatacgg actttctttc atcacgattt 2798521 gtctttgaaa caaaccgctg aagacatgca tatacacatc aatacattgc gttatcgtct 2798581 ggctaaggct gaacagctga cgggattacg ttttgaccgt accgaggacg tcgtcacgat 2798641 gtacgtcgca ctctattttt tagatcaaga tacaaaatag agagagtttc agtttcattt 2798701 tttgtatgtt tctccatgga aggctttgct ttttttcttt tacaatagat tgaaagcgtt 2798761 ttttgacagg gggatgggtg aaatgatcac caaggatgta aaggagcagc tgattcaggt 2798821 ctccggacca gaaaactttg atgactcgaa tgccggccgt ctcgtctatt catatgatgc 2798881 gacgcctcag tatcagtcta tgcctgatgc cgtgattgct ccgaggaata ctgatgaaat 2798941 atcacgcatt ttaacaattt gcagcgaaca tcgagtgccg atcgttccaa gaggatcagg 2799001 gacaaacctg tgcggcggca cgtgcccgac tgaaggcgga cttgtgcttc tctttaagca 2799061 catgaaccag attcttgaaa ttgatgaaga aaatttaact gccacagttc agccgggcgt 2799121 cattacgttg gatatgatcc gggcagttga aagcaaaggt ttattttatc cgcctgaccc 2799181 gagttctatg aaaatatcaa ctatcggggg caacatcaat gaaaattccg gcgggctacg 2799241 cggattaaaa tacggtgtca cccgcgacta tgttattgga ctggaggttg ttctcgcaaa 2799301 tggtgacatc atccgcaccg gcggaaaact cgcaaaggat gtggccggat acgatctcac 2799361 acgtcttttt gtcggctcag aaggaacact cggcattgtg acagaggcaa tcgtcaaact 2799421 cgttccaaag ccggaaacaa agaagacgct gcttgccctt tatgaaaaca tcgatgccgc 2799481 tgctcaaacg gtatcggaca ttattgccgc aaaaattata cccgctacgc ttgaatttct 2799541 cgatcagcct acactattgg tgattgagga ttatgccaaa atcggacttc cgacaagcgc 2799601 aaaagcagtt ctgttaattg aacaagacgg gccatttgaa actgttgaac gggatatgga 2799661 aaagattgag gcgatctgca aaaaaggcga cgccgtatcc gttcagaccg cacaaacaga 2799721 ggaggaagcg tttgccctga ctgaagcccg gcgttctgca ctttctgccc tagcccgcct 2799781 caaaccgacg acgattttag aggatgcgac cgttcctcgc tcagaaatcg ccaatatggt 2799841 taaagcgatt aatgatattg ctgctaaata tgatatttcc atctgcacct ttggtcatgc 2799901 gggagacggg aaccttcacc cgacatgcac gacagacata agaaataagg atgaaatgga 2799961 acgtgtcgaa caggcttttg ccgagatttt tgagaaagcg attgaacttg gcgggacgat 2800021 aaccggagag cacggagtcg gggaaatgaa agcgccttac ttggaaatga agctgaaaaa 2800081 agaaggcatt gatgcgatga aagcgttgaa agcggcattt gacccccgga acatattaaa 2800141 tcccggcaaa atgtttgcga aagatgccag aaaacgtgtg gtggcggaaa gatgacaaca 2800201 gaaaaagaaa tgaaacagat ccaaaatgaa tttaaagagc gtatggatga aggagagtta 2800261 ttaaattgta tgcgctgcgg cttctgtctt ccttcctgtc cgacctatat cgaatcggga 2800321 tttcaggaaa cacactctcc gcgtgggcgc atcgccttaa tgaaagccgt agccgacggt 2800381 atgattgaac cggatgaaga tgtcgaacgg tcgctgtcac tttgcctcgg ctgccgcgcc 2800441 tgtgagcctg tatgcccgtc tggcgtgaaa tacgggcagc tgcttgagga agccagagat 2800501 attatccacc aaaataaaaa acactctctt ggtgaacgtg tcatgcgaaa gacggctttt 2800561 cacgagctgt ttccgcatca aaaccgcatg cgctcagctg taagccttat cggtttgtat 2800621 cagcgttcag gactgcaaac cgctgtgcga aaatcaggca tgcttcgggt cctgcctgag 2800681 catttgcgga cgatggaagc tgttcttcct gatgttccaa aaagcaaaga catgaaacat 2800741 cggccgcgtt tcctgccttc cattggcccc atgaaaaaac gggtcgcctt tttttcgggc 2800801 tgcttaatgg atacaatgtt tttaccgacc aataacgcca cattgaagct tttacagctg 2800861 gcaggctgcg acattgtcat tccgcctgaa caggcttgct gcggggcgct tcatggacac 2800921 agcggtgaaa aaaacacagg gaaagagctc gcgaaacaaa atatcgctgc tttcgaagca 2800981 ttagacgtgg atgcagtcat tacaaacgca ggaggatgcg gagcctttct cactgaatat 2801041 gatcatttgc tgaaggatga ccctgagtgg tcggaacggg ctgccgcttt tgttcaaaag 2801101 ctgaaggatt tttcttctgt tttggttgaa ctcgatttcc atcaaatgga tctagcactc 2801161 gagacgcctc aggtcgttac ctaccaagat tcatgtcatc taagaaatgt gatgcatacg 2801221 tcactcgagc cccgccagct tcttaaaagc atcaaagggg cggaattcaa agaaatggag 2801281 aaagcagaca gctgctgcgg gtcagcggga atttacaaca tcgtcgaagt tgaaatgtct 2801341 atgaaaatac tggacagcaa aatggctgcc gtcaaagcaa ccgaagcgat cctcattgta 2801401 acagcaaatc ctggctgcct gctgcagatg aagctcggca ttgaacgcga aggactaagc 2801461 ggtaaagtca gagccgttca cctggctgat ttgctattag aagcagccgg gcacaaaaca 2801521 tcatgagaaa gcccaaaaca gacattgttt tgggcttttg tgcgttattc catcggactg 2801581 caaatttcga tataatgtcc atccggatca gcgatatagg cgaccgtctg cccccatggt 2801641 ttcactttcg gctccccgat aatcgatacg ccttgttctc tcatcctttt gatgaccgct 2801701 tctacatttt cagtaacaaa cccgatttca aatgtgtttg aagcagatgt atccggaatg 2801761 tccagcgccg tgatgtctct ggcgctttcc cgggtattaa gcgccaatat cgtagaccct 2801821 gtatcaaatt cgacatacgt gccgtgttca gcacgaatcg gcagtcctaa aatatcccgg 2801881 taaaaaatga atagcccgct tgctgtccga tacgtataga ataagatatt tcattgatag 2801941 attcattgcc aacccctctc agcattttca atagtccttc tagcccggta tagatgcttc 2802001 catccttaag ctcggatctt tccacatctg cgcccatttt ttcacagccg ccacgataat 2802061 gatgaagcct aacaccagca tgatgataga taatacgcca ttcaatacac tatatcctgc 2802121 tgcttcagga ttgagataca cattgcgcac catccaatag cccgcataat tgacagtgac 2802181 atataaatag gcaagcggga taaggcaagt cagaatgtac cggcgtttat cggcgatttt 2802241 cagcacgatc gtcgctccga taatcagccc cactgaagcc atcagctgat tagaaacgcc 2802301 gaagagcgcc caaatggaac cgatatctcc tgaatacagc aagtaccccc acatcaaaca 2802361 ggcaagcgcg ctggcaaata cagagcccgg aatccagtct gttttcttca gcggcttata 2802421 cacctccccg aagaagtcct ggatcaaata acgggcgaca cgtgtgccgg cgtcaatcgc 2802481 tgttaaaata aagaccgctt caaacataat gacaaattgg aaaaagtatg aggccaaatg 2802541 gctgaaaaac ggcattccgg taaaaatata agtcatccct accgcaagcg tgacggctcc 2802601 ccctgttctt ccttctaagt ccaaaccgat ttccccgctc aattcaggca aatgtacgac 2802661 attcatgcca agcgtacgga aaacctcagg cgtgctgtta atcgcaaagt aatcagcagg 2802721 ctgtaaagcg gtcgctgcaa tcagcgccat gataccgaca agacactcaa caagcattgc 2802781 gccaaacgca accggcttca tatcactcca tttattcagc attttcggtg tcgttcctga 2802841 gccgacaaag gcatggaacc cagagatcgc cccgcaggcg atggttattg agatgaacgg 2802901 ccagacaggt cctgccagca ccggccctcc gccttttacg aattctgtaa acgcagggaa 2802961 cggaatggac ggattgacga caaacacacc aacaatcaaa gcgataaaaa caccgatttt 2803021 cataaagctg cttaaataat cacgcggagc cagaagcagc caaacgggaa gcgcagccgc 2803081 aaaaaacgca taaacaggaa gcgcgattgc aagcgttttc gtatctagcg ttaaaaagtc 2803141 accgagcgcg gtagtctgta cccatggacc gataaagact cctgccatta aaaagagaaa 2803201 gccgaccgtt gaagcgagct ttaaatttcc cgttttctta taaaataagc ccacacccat 2803261 cgcaatcgga atcgtaatcc ccaccgcaaa tgttccccat ggattacgtt caagcgcatg 2803321 caagacaacc atcgacaggc ccgccattgt gatcgtgatg ataaacagca tggacagtcc 2803381 tgtacaaaat cctgcaacag ggccaagctc atccttcgcc acttccgaca gcgattttcc 2803441 gtttttgcgc atcgatgcaa acaacaccac aatatcatgg acggctcccc caattaccgc 2803501 cccgattaac agccacaata atcccggcaa atagccaaac tgcgccgcca gaattggtcc 2803561 gaccagcggc ccggccgctg cgatcgcggc aaagtggtgg ccgaacgaaa cccatttatt 2803621 tgtaggcaca tagtctttcc catcctcaag cgcatgagca ggtgttggct tgtcatcatt 2803681 cactttgaga accttcacca tcataaatgt tccgtataaa cgataggcaa tagccaaaat 2803741 acacattgat gctatcacaa ttgtaaccgc attcattttc tcccatcccc ttttctgttt 2803801 ttcataaata tatcataatt tcatggtgaa aagcggtcat tttttcctat acaaaaagcc 2803861 ggctggaatg ggccggctcg tggcagttga aagacaagcc ggagagaaat ctccggcttt 2803921 gctattctta tgactgtttt ttcaggcgga tcacattcca ggaaagcggc gtgaaatgag 2803981 cagttaagcc gttttcgctg acagacgatg atccgttgga atgcggaacg acattttttc 2804041 tgttatgctg gtttgttgct ttgatatcct gatgctcaag tacgatgtgc tctgcgattt 2804101 ggtaggattc aaagcctctg agcgaaatct ccgtctccat ctgatcctca gccttgttta 2804161 ccgcaaaaat agtgagtgtt tcttcctctt cagagtacac aacagcagca tcaacatatg 2804221 gcacatcagt gaaatcagaa caatcgtact taggagaaga aataagcggt ttcagtgact 2804281 cgccccttcc gtaaacagaa gcatgcatgt atggatagaa aatcggctgt ctccatgctt 2804341 ctccgccttt ttccgtcatg atcggcgcga tgacattaac aagctgtgca agacacgcaa 2804401 ttttcacacg gtctgcgtgc tgcagcatcg taatgagcag agagccgact aataaggcat 2804461 cttcaaaatt gtaaatatcc tctaaaatcg gacgcgcagt gatccacggc tcgacttttt 2804521 tatcagcctc atttgagtgg taccagacgt tccattcatc cagagagaga ttgatagttt 2804581 tcttgctgcg tgtttttgct tttacatagt cacaggtcgc agcgactgat ttgataaaat 2804641 gatccaaatc catagaacgt gccaagtagt ttggcagatt gttatcccgg tttccgtagt 2804701 aagtgtgaag agagatatag tcgacatgct catacgtatg ctcaagcacc ttcgcttccc 2804761 aatcgataaa ggtcggcata ccgctgtttg agctgccgca ggcaacgagt tcaattgatg 2804821 ggtcaaccca cttcatgacc tttgctgtct ctgcggcaag ccgtccgtat tcatcagctg 2804881 ttttgtggcc gatctgccat ggtccatcca tttcgtttcc taagcaccat gttttgatgc 2804941 catacggctg ttcatagcca tgcgatcttc ttaaatcact ccagtaagag cctttcggat 2805001 ggttgcaata ttcaacgaga ttacgggcgg catctatgcc tcttgtgcca aggttgacgg 2805061 ccatattgac ctcagtgttc accttttttg cccaagataa aaattcattt gttcccactt 2805121 cattggtttc tgtcgtttgc catgccaagt caagccgtct cgggcggttt tcgactggtc 2805181 cgacaccgtc ctcccagttg tatccggata aaaagtttcc gcccggatag cggatgatgg 2805241 gaacctgtaa ttctttgatc agcgactgga catcttttct aaatccatct tcatccgctt 2805301 cagggtgatc aggctcgtat atgccttcat ataccgcacg acccatatgt tcgataaacg 2805361 agccataaat ccgtttatct acttcaccga ttttatattc tttgtctaca atcattcgcg 2805421 cttttttcat cacacgtttc ctccttcatt aacctttgac tccccctacc gtcaggccgg 2805481 agataaagta cttttggaaa aacaagaaaa tgataatcac cggcaaaatc gcaaatactg 2805541 agccggatat aagcatgtcg taattatttc cataagggct cagcaagctg gacagcccta 2805601 ttggaagcgt aaacatttct ttcgaccgaa gcacaatcag cggccacaag aagttgttcc 2805661 agctgtttaa ggactgaagg ataatcatcg caccgaaagc cggtttcatc agcggtgcca 2805721 taatcctgaa aaagatgccg aattccgtac agccgtccat ccttgcagag tccagcagat 2805781 ctcttggaag gccaagagca tattgcctga aaaagaaaac agcaacaggt gaaacgataa 2805841 acggcaatat gacacccgta tatgaatcga tcaagtgcag tccgacagta agtttaaaca 2805901 gaggaagcat catcacttcc agcggaacca tcataataat cagcacaaga acaaagatga 2805961 tatttctgcc cttaaaatca taaaccgcaa gcccgtaccc gatcatcgaa gaaaaaaaca 2806021 gagtgagcac agtcgtaaaa agtccgagta caagactgtt aaaaaaccat ttgaaataaa 2806081 tgctgccgcc attaaacaga aatgtgtagt tatcaaaact catcactttt ggatcaatat 2806141 caagattcag ccccacacgc aaaagctcag atgacggctt taatgatcct aaaagcaaac 2806201 agaaaatcgg aaaaagatac aataggctca gcatcataaa aaacagggtc agcgcaattc 2806261 tataaacgct aaactgagga ctgtgccgca acatttatcc ctccccctta aacgagcctg 2806321 acagctttaa tgaaatcagg ctgacaacaa ggatcacaat caaaagcaca atgccgatgg 2806381 ccgctccgta tcccatttca ttgtaggcaa gtccctgctg atacaaatat ccgacaagcg 2806441 tcagaccaat attacccggg gaattattct gccaaaggac gtagctttcc tcaaacatcc 2806501 tgaagccgcc gatgatgctg atggtcagca catatacggt tacaggcttg agaaacggca 2806561 gcgtgatgtg cagaaatttt ttcattgtat tcgcgccgtc tatatcagcg gcttcgtaca 2806621 gctctttcgg cacattttgc aaacctgcta aaaagtaaag gatgttgatt cccatccatc 2806681 tccatgaagc aagcagcacc atcaaaaaca tgccggtatg ttcattgttc atccagttct 2806741 gaggtgaaaa gccgagttta agtaggatgg aattggccag agacgtttcc atttctccga 2806801 agatcagccg aaaaatgatc cccgcgacaa tggttgaggt caatgccggg ataaataatg 2806861 ctgatttaaa tatatttcta aatttgacca gctttgaatt caggaatatg gccagaagca 2806921 atggaacagg aatcagcacg atcagcgtcc aaaaggtgta ttccagcgta ttccaaaggg 2806981 cggtatagaa cgtcgggttg tttagcgctg tataattaga caatccgaca aaggacacct 2807041 ctcccggcaa aattctttgg aagctcatga tgaagacact aatgatgggg tatagaaaaa 2807101 atacgagaaa ggataaaacg aatggcgctg taaacagata gggcgccgct ttttttgaat 2807161 aaaacagatc tcgccagcct gattgtttcg cagctgaagg aacgggatga accgttcccg 2807221 ttttcacagg tttcatgaga acctccccgc tttcactttt tgaatgggat tctatttctg 2807281 tttcagttca cctgccgctc tgtccaaggc ttgtttaggc gttttttgct gagatttaag 2807341 cgcgtcgaac aatacgcttc tgttgacaag gtctgaagcc ttggcaaaat cctcatgtaa 2807401 ataaattgga ttgatttcat ccttgatatc gagcagcaca gaaaaaatgc ctgttccgtt 2807461 ttggaagtaa tccgtgtatt tgtttttctc tttcaattcc ttggagctcc aaacatccca 2807521 gcgaagcggg tcaaagccga gtacgctcca gagtttttta tttccttctt cagagccctt 2807581 cgcaaaggcc aaaaactctt ttgctaactc aacatgcttg gattgcttcg gtacaacagt 2807641 tgccgtaccg cccaaacctg ccgagcggtc gcccccctct ttccatgccg ggagcggtct 2807701 gatggcaatc ttccctttca gatcaggcat ataatcgata aatcttccca tataccaaat 2807761 cggcatgaga actgaagcag ctcctccttg gttcataaag ccgtagtatt cttcactgtg 2807821 atgcccgccg cccggcgcag gaatcatcgt tttatcattg atcatgtctt ttaaatattg 2807881 aagtgttttt acgttggtgt cattattgag gatcagcttg ccgtttttat caaaatagcc 2807941 tgagttttgc tgtgaaatca tagataagaa cgttgcggaa tcatttgttt ccaccgttcc 2808001 catcggcttc ccggtcactt tgcgcacttt ctgtccggct ttatggtaat catcccatgt 2808061 tttaatatcg tcaggattga cgccggcttt tttcatcaca tccatgttat aaaacatgac 2808121 cgttgtccct acatgtgtat cgagtccgta aagctttccg tttttgctgt acaatgtcag 2808181 ccgcgcctca acgaatttat cgcgatcctt ttcaatcagc ggagtcaagt cggcaagcgg 2808241 tatgtcagag cccttcaaaa agtttgaaaa acgggccaat tcgacatctg caatatcagg 2808301 aacgccttct cccgctatta gggagataga taagttatcg tgcatttgtc catatggata 2808361 aacgaccgta ttcagcttaa ttttgcggtc aggatatttt ttgttccatt ccttcaccat 2808421 ttccacatag aactgctcat gaagcccgtt aaatgtccaa aaggtcagct cagtttcacc 2808481 cgatttgccg gatgattttt ctgctgaaca cccggcaatg actaatgtca gcaacatcat 2808541 gagcacaaga aaacagacag tcattttttt catctgcgtt accccttcca ttcgaggtgc 2808601 gggctattca tatagaccat ggttgatcag cgttttgttt tcattgatga ttcttaatcc 2808661 ggtgcatcgg tctcttaagg tgtgcgcgtg tctgaaggca tttttgacgg aatcctgccc 2808721 gacaccgatt tcgtcaaaat acgcagggcc tccggctgat ctcagccaat cagccagcac 2808781 ttctcctctc gggagtgttt gataagccga ttggatggct tcccggcggc ttggtgaaaa 2808841 ttcgttcagc ccgtcatcct gagcgagctt tctgtatgtg tcagttaata aaacagcggc 2808901 acagcccacc tttgccccat gaagaatctg aggccgtttt ttctccatta actccatttc 2808961 aatccaatgt gaaatatgat gctcgccgcc tgatgccggt cgggaatgat ctaatgccag 2809021 catgacaagc cccgatacaa gtaaagactc catcaaaacc cgtatgccag tttccgtttt 2809081 catcgcaatg tcttctgtgt gttcaatgca ggcagcaagc gcctcctgaa cgatcttagc 2809141 tcctgcaggc gaataaggct caccggcaag atgccgggat atttcccaat ctgctaaaga 2809201 cgtgatttta ccgagcatgt caccaaagcc agccgccacc attgactgcg gtgccgcttt 2809261 taatagatcc agatcagcga acagcgcaga tggggccttc gtttgaatgg ttgttttcgt 2809321 gccgtataaa ataatcggcg caccggctga tgtaaaaccg tctacagatg gagcagtcgg 2809381 ataagaaata aacggcaaat ctctttgaaa cgccgcaaag cggacgatat catgaatcgt 2809441 gcccgaaccg actgcgatca tgacatccgt tggttgtttc gtatggatca gcacatgaat 2809501 gagcgatcgt tcatcagctg tcacatctcc ggcttcattt tctggaatga tcaggcactc 2809561 ggcctgaaat ccttcttgat tcagtcggtt ttctaaatca attcctgcaa tgcggtgtgt 2809621 attcgcgtcg cagacaagga caatatgttg attgtttttt cgttttacat aatccaaaag 2809681 cgaatcagct gcttgcttac cgagaacaat ttcttcaact tttataggca acgtcttttc 2809741 tccggcgttt tcaaaagcac gctgaacgtc agctgcgata cgattcatat cagaatcccc 2809801 tcctcagcca atttggttac atccttaata gaatccagca cataatccgg cgtgtacaaa 2809861 cgctgttcac cctgtttcgc agaaccagtt agcactaagg cgcttttcat gccataaagc 2809921 ttccccatcg caatgtcaga ttcaatgctg tctcctataa tcatgcattc atgtgcggac 2809981 agccccattg ctgtacaggc agcctccgcc atcagccatg acggttttcc gacaacaagt 2810041 tcagtcttcg cttgtgcaga agtctcaatt gccccgatca ttccggccac atcaatggca 2810101 tttccgtctt cgttcggaaa agagcggtct ttgtttgtag cgataatacg agcgccgccg 2810161 gcagccgctt gaaaggcttg atttaaatcg tcgtacgtga gcgtttcatg aagggagatc 2810221 acgagccaat ccgcttcctt cggttcgctc gcgttctgca caccggccag cctcagctcg 2810281 tcaaccaagc cttgctcccc aagcacccat acctttgaaa aacgataatg ttttttcaga 2810341 aaagccgctg tcacgcttga tgacagaaca atgtcgttta cgtccgtttc aatccccgcg 2810401 ccaagaagtt tttttctgca catggcacgg gagatattcc cccggttgct taaaaagacg 2810461 attttctttc ccattctcct aagcgttttg atcgcttctc ttgctccttc gatcaactca 2810521 tttcctctga atacagtacc gtccaagtca atcagaatgc cagccggtga cacaggcgta 2810581 tcatgactgg ccataatacg catttgctcc gtgttttcga taaaaatgct tttcatgcag 2810641 gactgtattg attggggtta catccttgtt cagcataatg gagtgatagg ccatttcggc 2810701 aaccgtttct aatacaactg cgttatgaat ggcatttaag gcgtcagtgc cccagcagaa 2810761 cggtccgtga ttattcacga gcacacccgg cacctgttcg taattatgat gctgaaaggt 2810821 ttccgctatg acttttcctg tattcagttc gtagtcatga atgatttctt catcgtacat 2810881 ttctcgagta catggaatcg cactgtcaaa ataatcagca tgggtcgtgc ctaacggagg 2810941 gatgtctctg cccgattgcg cccagcttgt cgcccattga gaatgggtat ggacaattcc 2811001 cccgatattc ggaaaggctt tatatagata aacatgggta ggtgtatctg aagaaggttt 2811061 aagcgagcct tcgacgacct ctccatcaag gttcaaaaca accaagtcat cggctgtcag 2811121 gtcgctgtat tcgactccgc taggtttgat gacaattctt tctttttcac ggtcaatgcc 2811181 gctgacattt ccccacgtaa aggttaccag ctgatgctct tgaagcttca ggttggcagc 2811241 cagcacttct ttttttaatg tttcaagcat gctccatcac cctttatcaa ttctttttgg 2811301 cggcagatga aaattgaaga tttttgatcg ttttcagacg cttcatgaca tggttttctt 2811361 ttccgaaata atgaaccagc tctttatatt cagcgtacaa tttttcataa accgcggcgt 2811421 tttcggcatt tggcgtataa gttatatctt tcagttttcc catgttcgcc gctgcctttt 2811481 tgatatcatc gtagccgcct ttttctttgc ctgctgcaag cgcgccgaaa atggcagatc 2811541 ctaaggctgg ggcttgcggt gaaccagaga ttttaatgtc catgtttgtc acatccgcat 2811601 aaatctgcat gacaaacggg tttttctcag ctattccgcc ggctgcgaac agttcctcaa 2811661 tcggaacacc gctttctttg aatgtttcga taatcatccg ggttccgtaa gctgtcgctt 2811721 caactaacgc tctataaatc tcttcaggct tcgtcagcag tgtcatgcca agcagcatcc 2811781 ctgttaaatc tgcatcaaca agagttgaac ggtttccatt ccaccaatct aaagcaagca 2811841 agccgctttc accaggcgct tgatggtttg ctttctcact cagcagctca tgaacgccaa 2811901 tgtttttttc ctttgcttcc tcttgataag ctggcgggac acatgttttc acaaaccagt 2811961 caaaatgatc gccgacacag gactgcccgg cttcatatcc cgcatagccc gggagaattc 2812021 cgttgtccac aacgccgcac attcctggaa cgatatgcac ctcttcacca agtagaacat 2812081 ggcacgtcga ggttcccata atcatcagca ttttccctgg ctctgtaatg ccgaccgccg 2812141 gtaccgaaac atgagcgtcc acattggcaa ccgcaacagc cgttcccggg agaagccctg 2812201 tcagctttgc cattttttca gtcagactgc cggctttttc tcctactgaa tgaatagaac 2812261 ctgacaattt gtcctttgta atcgttttca ttgaaggatt taatttctca aagaaatcat 2812321 ctgacggata ccccgctttt tcactccaca tcgctttata ccctgcggta caattgcttc 2812381 gcttgagcga gccgcacagc tggtacacga tccagtccgc agcctcgatg atccggtcag 2812441 ccgcttcata aatgtgaggc gcttcctcgg caatttgcat gacctttgga atcatccatt 2812501 ctgatgaaat ttttcctccg taccgctgta aaaaagcctc tccttcttct tccgcgattt 2812561 gattgagccg atcagcatgt ttttgggccg catgatgctt ccagagcttc acatagctgt 2812621 gcggctcctc ttcatattca ggcagcatgc ataacggctg cccgctgctg tcaataggaa 2812681 ggatcgtaca tgccgtgaaa tcaattccaa tcccgataat gtctttcggg tcaacgcccg 2812741 tctgttcgag taaagacgga atggttgttt ccaagacttc gaggtaatca gcagggtgct 2812801 gcagcgccca gtcacgcggc agcttttgac ccgtttttgg aaggacggta tcaatgacag 2812861 catgcctgta ttcttttaca gcagccgcaa gttcctcccc tgtttggaca tgaacgagca 2812921 ctgctcttcc tgataaagtt ccaaaatcaa cccctattgt gtaagccatg tgacatcccc 2812981 ctctactttt gaagccggta aagcgcctcg ttccatttta actcgtgttt cagtttatga 2813041 attgtcgtat cacgggaaat gagaacactt tcgattcccg ccatttccgc ccaatcaagc 2813101 atttgctccg ctgtcagttc ataagacagg caggtatggt gtgcaccgcc ggctaaaatc 2813161 catgcctccg ctgctgtttt caatgacggc tccggcttcc agagaacacg ggcaaccggt 2813221 aaattcggca tgtctttttc aatttcctgg ccgttgactt cattcagcac aaggcggaaa 2813281 cgcccgccaa tatcaacaat gctagcttga atggcagaac cgctgatgcc gttaaatacc 2813341 aaacgcgcag ggtcctcttt gccgccaatc gaaagcgaat gaacctcgat tttcggctga 2813401 tccaaagcga cagtcggaca cacttcaagc atgtgagagc ccagaatcat ttcatttccc 2813461 ggttcaaaat ggtacgtgta atcttccatg aaggaagttc tttttccttt agccatgatt 2813521 ttcatcatcc gtacaagggc cgctgtcttc caatctcctt caccggcaaa cccatagcct 2813581 ttctccatca ggcgctgaac ggcaagtccc ggcagctgtt tcattccgtg cagcacttca 2813641 aacgatgtcg taaacgctgt gtatccgcct tgctcaagaa aagcggttaa tccaagttca 2813701 attttcgcct gttctttaat ggacgctacc tttgcttcgt cacgttttgt ttcctcactg 2813761 atcacatata gtctgtcata ctcggcataa agcgtgtcaa cctcgtcgtc cgtaatgcga 2813821 tccatcactt caacgagatc cccgatgcca tatccgtcaa cctgccagcc aaattgaata 2813881 tgcgctccca ccttgtctcc gtccgttacc gcgacatgac gcatgttatc tccaaatctg 2813941 gcaaccttaa tatgtctgct ttcatttaat gcagccgccg tatccatcca ctgggacatt 2814001 tcttttttca cttcttcatc atcccaatag ccggcaatga cttttcggct aagccccatt 2814061 ctcgagttga tgtaaccgta ctctcgatcg ccatgcgcgg attggttgct gttcataaaa 2814121 tccatgtcaa tcgtacccca cgggatatcg cgattatatt gggtatgcaa atgcataagc 2814181 ggtttttgat aagaggaaag gccttctatc cacatttttg caggggaaaa tgtgtgcatc 2814241 catgtaatga tgccagcaca tgtctcactg tactccgctt ctcttaacag ctctctaatg 2814301 gtttccggtg aagtgacgac gggcttatga gtgattttat atctggaaga aatcccgctg 2814361 agcccctcac aaatgctttt agcatgctga tctacgagtt ccagcgtctc ttccccgtat 2814421 aggtgctggc ttcctgtcac aaaccagaat tcataatcct ttgtctgaag catgtaaact 2814481 gcccctttct cataaaataa aacgctttca aatacaaaag atacgtacta atgatagaaa 2814541 ataaacctat aaataaatat ttgtacgaac aattttatta tagtaattga ctattatact 2814601 gtcaatcttt tcttttaaaa aaagccgggg gcagagcccg gctttttaat tcaataggac 2814661 ggccagcccg agctccaatt caaatcattg atgagaagct ttggaatgcc gttgtcattg 2814721 gcatcatagg catggcgaac aagaatgttt ccgttcacaa tatcctggcc tccaggtcct 2814781 ttccattggt cattgcccga atccaaaatg gtgcctccgc cttcaagcat gctttttccg 2814841 cttttatcaa gataagggcc tgtaatgctt ttggatcttc cgtaagcaat tttgtacgta 2814901 ctgtttaccc cgtcacagca tttatcaaat gaaaccatta aatagtaata tccattttga 2814961 tacgtaagag taggagcttc taaggcacct ccattattcg gtctagctgc aatcgaatag 2815021 agcgagcctg taggcttcat tgtactctta tcgagcttag tcagcttaat gccgctccaa 2815081 aacgagccga atgcaagcca cgggttgcca tccttatcga atgtcagctc cggatcaatg 2815141 gcgttataat tatttgagct tgtcgaacgg atcaccaagc cctcgtcctt ccagcccccc 2815201 gaactgatgc ttgttgaaga tgccaggcca atggcagatg tattgcttcc aaaagaagaa 2815261 acggaataat atagccagta cttgccgtta tagtattgga tgtccggcgc ccactggttt 2815321 tggccataat tcggcacata attggaccac cacgatagcg gtgtagtgaa aatggatttt 2815381 tgtacggtcc aatttttagc gtctgaagac ttcaaaaccc gcagtccccg ttcttcagta 2815441 agccctgttc cgagcgcata ccatgagctc ccctctttaa tcatagtcgg gtcatgaagc 2815501 agctcattgg atgcacccca aaacgctgcc tctgcgggag cagcagaagt gaatatcaaa 2815561 cctgcagcca gagctgcact cgaaaagtgt aagaagcgtt tccatgtttt tttctttttc 2815621 aattttgttc aacctccttt attttagaaa gcgcttacaa attagattat ttatcctccc 2815681 ttcctgtcaa atcgactgcg tatcgtatat cgtcatgttc aggaaatttt cggtatcccc 2815741 tttattgtag tcactatgct gtaatttgta cagacaaaaa aatagaatcc acctcaatag 2815801 gcggattctt ccgtatcttt attggtacgt aatttcgtca accgtttttc ggtctaactt 2815861 cttaatgact tctgtaatta actttaccgc gttttcataa tcatcacgat gcagcatggc 2815921 cgcgtgcgta tgaatgtagc gggttgcaat ggtaatggac agcgcaggaa cgccatttgc 2815981 cgtcaaatgg atggcacccg aatcagttcc gccgccggca atggcatcaa attggtacgg 2816041 aatgccggct tcctccgcag tggctacaac tgcatcgcgc aaacctttgt gagagaccat 2816101 ggatgcatcg taaacgataa tctgcgggcc tttgcccatt ttgctctgcg cttccttctc 2816161 ggaaatgcca ggcgtgtctc ctgctatccc tacatcaaca ccaaacgcaa tatcaggctg 2816221 aatggtgtgt gcagccgttt tcgctcccct cagcccgact tcctcctgca cggttccgac 2816281 gccatacact atatttggat gatctgtgtt ttgtaagttt cttaacacat caatagcaat 2816341 cgcacagccg atgcggttgt cccaggcctt tgcgagtagg aatttttcat tgttcatgac 2816401 cgtaaattca aaatgcggaa cgatcatatc tcccggaagt acaccccact ccaaggcttc 2816461 ttcccggctt gaagctccaa tatcaataaa catgtctttt atttccactg atttttttct 2816521 tgcttcagga gacaaaatat gaggcggctt agatccgata acccctgtga tttctccttt 2816581 ttttgtgaca atggtgacgc gctgagcaag cataacctga gcccaccagc cgccaacggt 2816641 ttgaaaacgg ataaagcctt tatctgtgat ttgtgtcacc ataaagccga cttcatccaa 2816701 atgtccggcg atcataattt tcgggccgtt ttctgcacca gttttttttg caattaaact 2816761 gcccaggcga tctgttgtca cctcatcagc aaatggttct atgtatgatt tcatcacttg 2816821 ccttacttct ctttcattgc ccggtatgcc ttttgcatct gttaaatctt tcagcatggt 2816881 caatgtttca tctaattttg ccatgttcca aaccctcctt catcagtcct gcattcttat 2816941 tatacaaaac atggcgctaa ccatacgact atttcacttg aaaatcgggt atatgttttt 2817001 acagctttct tttagaaaaa gtgaaacctt tttctatgct tttcgtatta catcagatca 2817061 tcaccataag ggaggtgcct tcacacaatg tttgtcatgg ttctaaggat tattttgctt 2817121 gcactttttg cttattgtat ttatgccgtg gtcaaatatg tcgcgaatcc taagagaagg 2817181 cttaagctgg cccaatcaaa agaacatttt tatattattg atgaacaaaa caatacccgg 2817241 aagaattttc agctgacgta taaaggcgtg ctttttgagg gagaaaagca tattccttcc 2817301 aaggatcatc cgctgtttat tcacacgatc tttgtctgga cagaatctcc tgagaagctg 2817361 aaacatttct ctgcaaaaga ttttgagaac attgaagaaa aagtgctgga acgatatcca 2817421 aattgtaaga ttgactggga ccagcccatt aaactcgcaa aaaaagcaga agagcgttaa 2817481 acgcttttct gctttttata aatcaaacgg gctgtagtaa atagcgatga gaatcgcttc 2817541 tattaccaga agaagcggta ctccgtactt aaaagaagcg tgtttcgttt tatgtctgaa 2817601 ggtttgcatg ccaagccaga caccgagcgc tccaaacacg atggctatca gccacagccg 2817661 gtcttcagaa attctccact tgtgctgctg cgctttgcgt ttgtcaatgc ccatcaccca 2817721 aaaaccgcac agattaatca acaccaaata agcagcaata atcatgttgc ctcatccttt 2817781 atatagaaaa agccgctctg ctggagagcg gctctatatg attacttgtt taattgagct 2817841 ttagcagcat cagcaagctg attgaatgca gtaagatcgt ttacagcaag atcagcaagc 2817901 attttacggt ttacttcgat accagaaagc ttaagaccgt gcattaaacg gctgtaagaa 2817961 aggccgttca tgcgagcagc tgcgttgata cgagtgatcc aaagtttacg gaaatcacgt 2818021 tttttctgac gacggtcacg gaaagcatag tttccagatt tcatgacctg ctggttagct 2818081 actttgtata atgtatgttt tgaaccgaaa taaccttttg ctaatttaag aaccttttta 2818141 cgacgcttac gtgtaacagt tccgcctttt actcttggca ttgaatttcc ctcctaattg 2818201 ttccttatcc gattacttga tgttagcaag catttgtttg atacgtttga agtctcctgc 2818261 gcttacaaca gcactcttgc gaagcttacg cttttgcttt tgagatttgt tggcgaataa 2818321 gtgacttgtg tacgcgtgag aacgttttaa cttcccagaa cctgtctttt taaaacgttt 2818381 agcagatccg cggtgagttt tcatttttgg catgggattt cctccttatt gcttttcgtt 2818441 tttcggtgcg agcattaaga acatgctgcg gccgtccatt tttggttttg tttcgactgt 2818501 cgcaacctca gcacatgctt cggagaaacg gtctaataca cgctgaccga tttctttatg 2818561 agtgattgcg cgtcctttaa agcggataga agctttcact ttatcgcctt tttcaaggaa 2818621 tttaatcgca ttgcgcaatt tcgtgttaaa gtcatgctca tcgattgtcg gacttaaccg 2818681 aacttctttt aagttaatga ttttttgatt cttgcgtgct tctttttcct ttttctgctg 2818741 ctcaaatcgg aacttaccgt agtccatgat tcggcagaca ggcggttttg cattcgctgc 2818801 aactaacaca aggtcaagat ttgcgcggcc ggcgatttca agtgcttcct gacgggactt 2818861 gattccaagc tggtcgccat tttgtccgat taaacggacc tcacgtgcac ggataccctc 2818921 attaaccaat tgatctttgc taataatgag ccacctccat agtttcttcg aattgattca 2818981 caactcattt tgaatgcatt ttgcaggcaa acaaaaagtg tgggcattat aaaacaccca 2819041 cactacgaac atctgtatca ataaaaatgt acggtcaacc tgccaactac atgcatgtgt 2819101 caatcaggtg agaagcgggt gcttctgctt gtgatttata ttcaattcaa taactattct 2819161 acacaatacc ggatctttag tcaaggacga cttatccgga acaactttta cattgtaaca 2819221 tgggttttct atgagcgcaa gagagaaaaa gaaaatcttt catccccacc cagaatacaa 2819281 agaaccaaca attccccctt attacgcaat ttacaacaaa accaccgaca ggaagaaatg 2819341 taaaacaaag ttaatctctg accgatataa ggagcagaag ggagcctgac acatgaacaa 2819401 actgatacag cttgctttat ttttcacatt gatgttaacc ggttgctcga atagcagcac 2819461 atcttccgaa tcaaaagtcg aaaccactgt taagacaacg gcagcatttc ctcaaaagga 2819521 gctggagaaa gagctaaaaa aactaaaacc cgtttcattg gacatgaagt tcgagagtcc 2819581 actcgctacc gagttaggaa agcggaaggc aaaagaggaa gctgaaaagc aaagacaaat 2819641 cgccgctgag aaaaagcttg aaaaagagcg ggaggcgaaa cgaaagaaac agcaggagga 2819701 aaaagcggag agacagcgat tagcagagca gcaggctgca gagagacagc gattagccga 2819761 agcggaaaga caagctgaac ttgaaagaca gcggcaggca gcaatccaaa aagagcagaa 2819821 agcgaacgct gagaaaaagc ggcaatcgca ggcacaacgg cagcagactg aggcaccctc 2819881 atctaatagt caagatccac catcttcctc gagtcagaca gataaaacca ttcaacagcc 2819941 agcttcagag cttcctgatg acgatggtta tggttatgaa gaacgaaaaa agtggcatga 2820001 cgatcaagta gaatggggca ttaaacaagg gtatatcgat cccgaagacg caccataaaa 2820061 taaaaaaagc caaggcattc agccttggct tatcctccga tcagctgcac gaacacaggg 2820121 atgaccagaa ccgttaccac tcctactacg acaacagcaa tacttgccat cgcagcttca 2820181 acttctccca tctcaatccc gaccgctaca ccaagtgcat gtccggatgt tccaagagcc 2820241 aatcctttag aaatcggatt tttcacttta aacaccttca agaacaatgc tccgagcgca 2820301 tatacgatga cagcgttaaa gatgaccgca aaggctgtga tgtcgctgat gcccccgatg 2820361 ccttttgata aaggaagcgc aattgccgtt gtagccgcct gcggaagcat gcttttcatt 2820421 acggccgaat cgagatgaat gcctttagcg agcagataaa caatcgtgac agagcagata 2820481 gagccggcaa taatggaggc catgatttgc caccagtact ttttaagctt atctctttgt 2820541 ttgtacaaag gaattgcaaa tgcgatcgtt gccggttcaa gaaaaaactt aatgatctct 2820601 cccccgttat tataatccgc gtaggaaaaa ccgccgattt ttaaaaatgc gatccccagc 2820661 accatggcaa caaacaaagg agtgaaaagg aagaagcctt tcgttttctt aaataaaaag 2820721 gtgccgatgc cgaatgcagc aagtgatacg acaatcccaa aataaggact cattgtgctt 2820781 tccatgtgaa gaacctcctg tttcccttaa tggtgaacga gttcgttatt gttctgcggg 2820841 ctttgcactg tttttgtttt catgtccgct tcggttttgc gttttccgct cagcgacaga 2820901 atcagctgag aaaacaatcc cgtagccccc agcaaaataa tcgttgcgag cagaatgaca 2820961 agaacaattt gcaggccgta ttgctgcatc acaccaagcg aattcataac agatatacct 2821021 gatggaacaa ataaaaatcc gatcagagag gttaaagacg ttccgagcgt ctccacttgt 2821081 tccagtttaa tgactttcaa acataatagg agaaataata agaccaaccc tacaaccgat 2821141 gccgggatag gtattgggac aatagcggca atcatatttg aaaccagcat aatgacggca 2821201 aaaataaatg cttgtgttaa aaacccgtac acttttttag cactcatttt cttcacctct 2821261 ttctctttgg taccctcatt ataaataaga attccctgtt ataaagcgct tacaagataa 2821321 catgccgtat agcgggtctg agttgcagaa tcaaatggct gaaatgcaaa aagccgccca 2821381 tcaaatatgg agcagctttt tcaattcctt cgcatatgtc cggctgaccg gtattttcga 2821441 tccgtctttc atgatcagat tatacgttga attaaaccat ggctgaattt ctttaatata 2821501 ttcagtattc acgacaaagc tccgatggac gcggataaaa tcagaatccg gcagcttttt 2821561 ctcaatcaca acgagtgtat cgctgaccgt ataagaatga tcgaaggttt ttacattgac 2821621 atgaccatct tctgttccgg catagataat gtccttcgta tccacaatca caatcgattc 2821681 ccccacagat agcgcgagct tgtgctggcc ggcatggctg ttttgctctg tttctacaat 2821741 atcccgattg acttttttat attttttcag cgtttgctga attctttctt catcgaaagg 2821801 cttggttaaa taatcaagag cgtccacctc aaacgctttg agcgcatact ggtcatacgc 2821861 tgtcgcaaac acaatagcag gaggatgctt cattttcttc aatcgctttg cgatatcaaa 2821921 accgttttct ccggataaat caacgtctaa aaacagcaaa tcaggttttt gatccatcat 2821981 ttggtcaaaa gcggattcga tattttccgc ttcattgatt tccatttcat cattggtccg 2822041 cttaagcaag taagccagtt catcccttgc cagcatctca tcatcaacta ttaacaccct 2822101 gagcatgttc ttctccctct ttcatctgtt gcattggcac ttgaaaggaa acctctgtcc 2822161 ctttatgaac ctcactgctg atatgcagtg cagcctgctg tccgaataaa ccgatcagcc 2822221 gctgatttag gttataaagc gctgtaccgg ttccctcctt agacggaaac ggtttcttcc 2822281 ccagttccgg caagacgtcc ggcggaattc cgcgtccgtt atccgccacc ttcatataga 2822341 cggatgcatc atcagataag acacagactg taaccttgca tatgtcttgt tttttcggaa 2822401 acgcgtgccg aagcgcgttc tcgacaagca cctgcaaaac aaacggaggg atttcaatct 2822461 gctccagtct gctgtcgata ttaagctcaa ttttatattt cccgggaaaa cgcgcctgtt 2822521 ctaatgacaa ataggcgtta agatggttca gctcctttga gagcggaatc agcagctgtc 2822581 tcgctccttg aaggtttgaa cgaaaataaa cactgagctg caataggagc ttacgggttt 2822641 tttcaacatc tgtacggcat aacgcagaaa tcgtgttgat cgcattaaat aaaaaatgcg 2822701 gattcacctg tgcttgaagc gctttaattt cagcatcctt gagaagtttg ctttgcagct 2822761 ctgcttcccc aagctcaagc tgtgtcgaaa acagcatggc cagcccctcg gcaagttcct 2822821 cctctacctg actcaggcct gccgggcttt taaagtacat ttttaaggtg ccgattgtat 2822881 tgccgttcga tgtcagcggt aggacaattg cagcgtgcaa agggcattca gcatgcgtgc 2822941 attcaatctc ttcctgcgaa atcgccttca taatatgccc tgttttaatc acctttttgg 2823001 acaggccggt gatcaagctt ttcgatggga tgtggtgatc cattcccgca ccgacatgcg 2823061 caaggatctt ttctttgtca gtgagagaca ccgcatctgt tcctgtcagc ttatggataa 2823121 tagccgctac acttttacag gagttttcat ttaatccttg gcggaaaaat ggaagtgtct 2823181 gatcagcaat cgtaagcact cgatgcgttt cgagagccct tgcctgttct tccttgcgaa 2823241 tgatcgcttg aataatagac agaaaaataa aactgcctgt tccattgatg agtatcatcg 2823301 gaattccgat catgctgaca agctcccaag cgtcactgaa cggctttgcc atcagcaaaa 2823361 taatgatcat ttgcagtgac tccatgccga ttcccacaag agcggcgatg cgcggtgtcg 2823421 gcattcgata tcgcttcgta aaatacctgc cgatcaagcc tgcaagaaca cccgctaaaa 2823481 tagatgagac ggcacagctt aaggccgtgc tgccaccgag tgaaaaacga tgcaggcccg 2823541 caagtatgcc gatcccagcc cctacaaaag gacctccgag aaggcccccg atttccacgc 2823601 ccaaaatacg ggtattcgcg atagagcccg atggatctat cgtaaacacc cagtcattgt 2823661 ttacaatcat atttctttga atttcgatgc ctgtataatt gctgatgatg ctgaaaagag 2823721 aaaaaataga aattaaaatc gcttttcctt tatagccgtc ctgattctga agagcttgtc 2823781 tgaaaagttt cgtatgggcg agaatgaacc ctaatataac aataatcccc actctctcca 2823841 gcatcataat cattaaatga atcattcatg tcacctgttc tttccgtttt cattctagca 2823901 tgttttcgtt ttgcggctga ctgttttttt aaaatcgtct gaaaacatat ttcacaaggc 2823961 ttttatctat tgtaaaataa aacatgagcc ttttggcaga aagatttgaa tctgaagcag 2824021 aggagaagat catgaaagcc gtattttttg atttagatga tacactactt tgggacgaaa 2824081 aaagcgtcag aacaacattt gcagaaactt gcttacaggc ggagaaaaaa tatggccttg 2824141 cccctgagga attcgaagca gctgttcgcg aagcggcgag agaattgtac atgtcatatg 2824201 agacgtatcc atatacagtg atgatcggca ttaacccgtt tgaaggactg tggtccaatt 2824261 tctcagagcc aatcagtgaa ggctttcaaa agctgaacaa gattgtgccg gagtacagaa 2824321 gaaatgcatg gaccaacgga ctgaaagcgc ttgggatcga tgatcctgca tatggcgaat 2824381 acttgggaga gttttttgcg gcagagcgca gaaagcgccc gtttgtatat gatgaaactt 2824441 ttgctgtact cgatcaatta aaaggcaagt atgaattatt gcttttgaca aatggcgatc 2824501 ctagtctgca aaaggagaag cttgccggcg tgcctgagct cgctccttac ttcaatgaaa 2824561 tcgtcatctc gggcgcattc ggcaagggca agccggatgt ttcaattttt gaacactgcc 2824621 ttaagctgat gaatattgaa aaagacgatg ccatcatggt cggcgataat ttgaatactg 2824681 atattttagg cgcttcaaga gccggaatca aaaccgtttg gatcaaccgg actgataaga 2824741 aaaacgaaac tgacgtaaag cctgattaca tcatcagcag ccttcatgat ttgtttccta 2824801 tattagagaa ataaaaaaag catgatctct tcaatgagat catgcttttt tattttattt 2824861 tttcgcttca gctactgcct ttttcacaaa ctcatcaagt gaaatggttt cagagttctg 2824921 ttctccgtat ttacgcacgt ttaccgctcc gttttctgct tcttggtcac cgaccaccag 2824981 catgtacggg attttttgca tttgcgcttc acggattttg tagccgattt tttcatcgcg 2825041 gctgtcgact tcaacacgca ggccttcaca ttgcaggcgt tcctgcactt ttttcgcgta 2825101 gtctaaatgc acagccggag aaaccgggat gacttggaac tgaaccggtg caagccatgt 2825161 cggcagcgcg cctttgtgtt cttcgattaa gaaagcaaca aagcgttcca ttgttgaaac 2825221 gacacctctg tgaatgacaa ccggacggtg ctgcttgccg tcctcaccga tgtatgtcag 2825281 gtcgaaacgt tccggcaata agaaatcaag ctgaaccgta gacagtgttt cttcttttcc 2825341 gatcgcagtt ttcacctgaa catcaagttt aggtccgtag aatgccgctt caccttctgc 2825401 ttcgtaatag tcgtggccga tttcatccat tgcctctttc agcatggatt gcgctttgtt 2825461 ccacatttca tcgtcatcaa aatatttctc tgtatcttcc ggatcgcggt aagacagacg 2825521 gaatgtgtaa tcacttaaac cgaagtcttc ataaacatcc tggattaaac ggactgtacg 2825581 gataaactca tccttaattt gatccgggcg cacaaagatg tgtgcatcat ttaacgtcat 2825641 tccgcgtacc cgttgaagtc ctgacagcgc acctgacatt tcatagcggt gcatcgttcc 2825701 aagctctgca atacgaatcg gaagctcgcg gtaactgtga atgtcttgtt tgtaaatcat 2825761 catatggtgc ggacagttca tcggacgcaa tacaagtgtt tcattgtcca tttccatcgg 2825821 agggaacatg ccttcctgat aatgatccca gtgtcctgat gtttcataca gctctttgct 2825881 gcctagcaca ggtgtgtata cgtgctcata gccgaggctg atttctttat cgacaatgta 2825941 gcgctcgatg acgcggcgga ttgttgcgcc ttttggcagc caaagcggca ggccttgtcc 2826001 gactttttga gagttcgcga acagctttaa ttctttgcca agctttctgt ggtcgcgttc 2826061 tttcgcttct tctagcatac gaagatgctc ttcaagatca gcttttttga agaaagctgt 2826121 accatatacg cgctgaagca tttggttttt gctgtcaccg cgccagtatg cgcctgcaag 2826181 gcttaacagc ttaaattctt tgatttttcc ggttgaagga acatggacgc cgcggcacag 2826241 gtcaaagaat tcgccttgct catagatcga aacggtttct ccttcaggaa tcgcatccaa 2826301 tagttcaagc ttcaggtcgt cgccgatttc cgcaaaacgg gctttcgctt cttcacggct 2826361 gacttctttt cgaacgatcg gaaggttcgc attaacgatt tttttcattt ctttctcgat 2826421 tttcggcaga tcctccggtg taatcgcttc gtccatttct acatcgtagt aaaaaccgtt 2826481 ttcgataacc ggaccgacgc cgaatttaac atccttgtag atgcgtttaa tcgcttgagc 2826541 cagcaagtga gccgcactgt ggcgcataat ttgaagacct tcttctgagc cttctgtaat 2826601 gatttccact gtaccgtctt cattgatcgg cgttctcaaa tcgatttctt ttccgttcag 2826661 ttttccggct aatgactttt tctttaatcc cggactgatg gatgccgcga tatcttctgt 2826721 tgttgttcct ttcgcaaact ccttgactgc tccatcagga aatgtgattt ttaccatatc 2826781 tgacatcttt gtcactcctt tttttgcata taaaaacccc gccccctatg aaagggacga 2826841 ggttgaataa acggaatcgt ggttccaccc ttttttccgc aaagccaata cacggcacct 2826901 gcggctctaa gctctgtaac gggagttccc gtcagccatt actgttcctt ttcaagaggt 2826961 tcacagctga agttcaaagg cggtaaagcg aatggtcctt agctgggaag cttgcagcca 2827021 gggcttccct ctctttgagc cggtatcatt ccttcgtgtc cttatcaata cgtgtgtctt 2827081 tcttaatctc ctatgtatta taaattgttc aatccaaaaa atcaacacga tcgcgtttcc 2827141 ttttttttaa accgacagcc ttaaatagac aggctgccgg ccctcatcct tccgagtgct 2827201 tcaccggtat ttctgcatct gtaaaagcat gcagcgggag catttccact ctctcttgaa 2827261 atacgttttg aatggtcctt gccatcatgt gctcgggctg gtcggtataa agcacgactt 2827321 catcaggcgc aatggaaatc agcggcgcga gcaaatgaga atcaatatac ataggatgat 2827381 cccggacaaa tcttctgtct atgtatttca ttttttcccg ttccggcaca tagcgcagct 2827441 cccataatgt aaaggaacca tcatggacaa tatgcacttt tttgattcgc ggctgtttgg 2827501 cgtccacata gtctctgagt gtttgaataa agttttgata ttcctgttcc atcttatatt 2827561 catcaatcgc tgcttctgta atatctctca gctgcttata gtatgatcca agtcggaagg 2827621 tctgaaagga gcgaatgtaa aatactcctt cctctaaaca gatcgtttgg agttcatcca 2827681 aaattgattg tttccgtgaa agcttcagcg gctcaaacgg aagatcgtct gcttcacctt 2827741 caataatact gtgtgcgagc tgaaggattt gctgctgttc atcctggtcc gtgaaacaat 2827801 acgtttcctc aatcaatgac agcatatgct cgtcttcttt gcattccaaa aaaaatttga 2827861 ccagaatcgg ctccataaaa cgctgaatag gaaaagccgg attcgctttt tcaatcccga 2827921 tttttcgtat gccttcacgg acaatgatat tgttccgatc gtccgaatgc tgaatgagat 2827981 gtaaaaaagc ggctgcatca tggtcatctt caaagattat ttcaagcatg tttgtccccc 2828041 cttacggcat ctgttacaag tatatggggg atgtttttaa aatagacgta aaggtcattg 2828101 gcaaatctta atttgattct tggaacaagt tttgcatttt ctttctgaag atgaacggca 2828161 atgagataaa cacgatatac aaagcgagca ccataaagaa agcgggcaga ttgccagcca 2828221 aaaagctcgc acccagcaca ttaagcgcaa tcgtcccagg gatgattccc acagccgttg 2828281 cggcaaaata cggcagcgct ttgacattgg aaaggcctgc cgcatagctg acgaaatcaa 2828341 aattgatcgg caggattctc aaaagaaaga tatagaaaaa tccgttatcc tccatttgct 2828401 tctgtatggc ttcaagcctt tcgtaatgcc cgttcttttt cgccgaaaac aaaccagccg 2828461 caaaaaacga aacagctgaa gcgcacatcg aaccgaataa cgtataaagc gtgccgagaa 2828521 gcgggccaaa cgcaagtccg ccagctattg aaataacaga caccggaaat aaaacaagtg 2828581 gcctgacgat ggatatcccg ataaacatca gaggtgcaaa gactccgaac gacaataccc 2828641 ataccctgat ttctttcggc gatacattca aatacgtttt atttccccaa tagagtaaac 2828701 cagcacctgc aagcactgcc agccatttga cagccgtttt tcgtttcata ccctcagttc 2828761 cttccccttt gaaccacagc aattatggat gtcggcggtt ttctccgtca aggcggatcg 2828821 gagcagccaa atataatatc cgctccatta atcttgcagc ttttacttct tctttttctc 2828881 ccctctgcga atacgtaaaa tgatgcttca gctcgtcagg tgagaaatta gaagaaaaga 2828941 acgttggcag ctgctgggac attctgtgct gaagcaccgt tccgatgacc tcatccctta 2829001 cccagcttgt cattgattct gctccgatgt catcaagcat taatacgggt gtggtcttta 2829061 ccatattgag cttctcttcc aatgtctggt cttgcagcga attcttaagc tctctcacaa 2829121 attcaggcac ataaacaatc atggaggaat actctttttc cgccagctca ttggcaattg 2829181 cagcgagcat aaacgttttt cctaccccaa atttcccgta taaatataat cctttccctt 2829241 ttcccgtctc attatagctt ttcaggaagt ctgtaacatg ctgaaacatc gcgagtctgc 2829301 ttgggtcact gatatcaact tgctggaacg tcgctccaag aagatcctgc tggatataca 2829361 tgcttttcat aagagactgt tgtttcttct gctggtcgag cttccgtttg actggacatt 2829421 cgtaatactc gatatcaata gacctcccat tgacaacaag cttcggatgg tagccctcca 2829481 acaaattgtt gcagttttca tcttccgaac aataggagca attcttgctt tgttcgatat 2829541 attcataaag cttatttaag ctcttttcga tcattttttg gtcaatcact tcttcgtttt 2829601 ccttcaaaaa tgcttgaaca tcttgatctt tcatgacttt ttccttcatt tgttcaagac 2829661 gtttttggaa atccggcctg ccggttacgc cctgcaggga acggccgatt ggttccatct 2829721 attccttcac cccgcatctc tgtctttaat aggcagagta ttttttcagt ttttgcattt 2829781 cttccatcat ctttttcttc tgttcttcca aatcctgcgg atgcagcttc tgctgtccgg 2829841 attctgaatc ggacgctgtt tccttttctg tcatccaatc aggaagcttt tcttcacgaa 2829901 tcactttttg gtttcgtttc gaagactttg tttttccctc agcccattca agatactggc 2829961 ggttttcttc tattgcgagc ttcatcgctt ccctgaccgt tttcaccttt ttgcgtgccc 2830021 aatgcgaagc gattttttgg atatagtttt tcgacagctt catgtcggtt ttcagcatga 2830081 cataataaat taacacattt gtgacgcctg gctcgagctt ctgttcgaac ataatttctt 2830141 ctatgatctt cagatcagct tttgacggct ctgttccgtc agcaatgtcc tgcagaagct 2830201 tcttcgggga aatcgcctcc agcaatgcaa tcagcttccc atccagagaa tcctcttctg 2830261 ccggttgttc gccttcacgc agatgcaccg gctgtgtttt ttccaccaaa tcgggcagct 2830321 gtccgtttct ttcaatttga taccagtcgc tcgccgcttt tcttaatgcc tccgtcgtaa 2830381 tgacgtcacg ctcatcaatt gcgctcatca caacattttg catttgcaaa gggtcaattc 2830441 cgtacagata agaaagcttt ttgattgtgt cccgcacctg ctgggtcatc gcttttctcg 2830501 gtatcatcgt ctcagaaagt cccgctaaaa acaaatcaaa atcaaacaca tcctccgtta 2830561 tggtgtagga cggagactgt ccgacagaag tatactcgga cccctcggca agccttaccg 2830621 tttcctccat atcggatgtg agcttccatt cactcggctg cagcgattca aacgcatgat 2830681 taaacggacg cgtaatgtcc ttcgcatctt ctgaaatggc cgggtgcgta aaaaattgtt 2830741 ttaattgctg atatttcgtt tttccgaccc tattatacag aaaaacattc agcattccgt 2830801 cttcaaaaaa ttcatttggt ctgagcggcg gaaggagttc atatataaag aggcgctcct 2830861 gccgctcgga ttctttcata tatactttca gcaatccgat gccctcgagc ttcccctgtt 2830921 cctgatggat cgtttttaag ttggactgtg tcatccccat cagctgtcta tgtgtggact 2830981 ctccgcccca cagacggttt tgttcaagct ctccccacaa tgtcatataa agagagaatg 2831041 caacagggcc gattaagggc tggtacagtt gtgtaataat ttgtctgtca atatcctgca 2831101 gcatcgatct gcttttaacc acatacgggt ctacaggcag tacatctttc caatagtcag 2831161 ccatacattc tcaaaccttc cgaatttgtt tctacctttc attttacacc gtttcttata 2831221 tctatcaaat gccaattttg cacatgagaa aagagctaga agaatcctct tagctctttt 2831281 aacgctcttt ctttattaag tcttttaatt catcgataaa gacgtttata tctttaaact 2831341 gccgatagac ggacgcgaac cgcacatatg cgacttcgtc aatcttagcc agccggtcca 2831401 tgaccatttc tccgacgagc tcactcttca cctcggagca gccttgattg cgaagttctt 2831461 tttcaatatc aaagcacatg tcttcaagcg ttttgagtga aacaggcctt ttttcacatg 2831521 cttttatgag gccgcgcagc attttttctc tgctgaattc ctcacgcaca ccttcttttt 2831581 tcacaacgat gagcggggtt tcctccactt tctcaaaggt cgtaaaccgg tagtggcagg 2831641 attcgcactc gcgtcttcgg cgaatcgact ttccgtcatc cacaggccgt gaatcaagga 2831701 ctcgtgttcc gttatgctgg catgaaggac atttcaataa aatcagctcc caactatatc 2831761 gttccctgca atgtattttc ggcagcctcc gccttttaaa aatagatgtg acagcatctg 2831821 tcgggagagc cgttgttaaa tttgtttcta tagcattagg tggtttgtga aaatctcctt 2831881 cttattttac aaaaaaaatg aaaaaagaaa aagctgacac tctcgtttct ttataaaaat 2831941 aaaaggagca taagctaaaa agcgcataat ggctttctag cttcagctcc ctttgtgttc 2832001 gcaatttact ttatagtact ttcgcttgcg cctgtttaat ttgcacaggc cccattcctc 2832061 ttggtatttc aatgttttct cttgtatcag catgtaatgc ctctgcaatg taatcagcag 2832121 cgacattagg atctaagtct ccacaagtat aaacatcaat gctcgcatat ccgtgctcag 2832181 gaaaactgtg aatcgttaag tgtgattcag aaataatcac aactccgctt acgccttgcg 2832241 gtgcaaattt gtgaaatgca acctcgcgca cctcagcacc tgattttaga gcagcattta 2832301 caaacgtttt ttcaataaaa tccatgtcat tcagcttatc aaaatcgcat ccccatagct 2832361 cggagataac gtgacgcccc attgtttcca tagtcatgga ccccccttaa caagaattaa 2832421 aaagtgaaat tccaacaact gggtcggcca tttaccacgg gggaaagtta gtccggagag 2832481 gtcctaaccc tttaagtaat tccgaaacag tctcaagcaa gaagttcacg aaaaatagta 2832541 tactgtgttt aagtctaatt tgcaaggtgc gttttttcag aaatatgctg ttaagggttt 2832601 tttctttaaa atgtgtccat gaccttattt tatacagcag acggatgttt cattcgtgcc 2832661 gctacatggc ggattagatc aacaactctg caggagtagc cccattcgtt gtcataccac 2832721 gccagcacct ttactttcct gtcttccatt accattgttg taagcccgtc aatgaccgct 2832781 gaatgcggat tcgtattata atcagtcgaa acgagcggtt catctgagta atcaagtaca 2832841 ccgtacatcg acgttttggc agcgcgttta aatgcctcgt ttacttcttc agccgtaaca 2832901 tccgttttca gatcaacaac gagatcaacc aatgagacgt tcggaacagg gacacgcaag 2832961 gcgaggccgt gaagttttcc tttcagatgc ggcagcacaa gcgaaagcgc ctttgccgct 2833021 cctgttgttg ttggaatgat ggattcaccg caagcccgcg cccggcgcaa atctttgtgc 2833081 gggttatcaa tatttttttg gtcattcgta tacgcatgaa ctgtagtcat cagaccgctc 2833141 tcaatgccaa actcttcatc cagcactttt acaacaggcg caaggcaatt tgtcgtgcat 2833201 gacgcatttg aaataatgac atggcgctca gcgtcgaatt ggtcctcatt tacgcccatc 2833261 acaatggtaa cgtcttcatt ttttcccgga gcggtcaaaa tcactttttt tgcacctgct 2833321 tctatatggc ccatcgcttt atctttagca ttaaacttcc ctgttgcttc gacgactatg 2833381 tcaatatcat attcccgcca aggcagctgt tttggatcac ggctgtttaa caaaagcact 2833441 ttctttccat ttacgatcag gctatcttca ccagccacaa cctctttgtc gtatctgccg 2833501 tgaattgtgt catactttat taaatgagcc agcgtttctg cggaatagct ggcgttaatg 2833561 gccactactt gaatttgatc gtctaacatc gcttttctaa aaaccattct tccgattctt 2833621 ccaaacccgt tgatcgctac ttttaccttc atgttggaca ccccttatca attatgccat 2833681 cctaatttgt tactatctaa aattagtata acacattaaa acaaattcgc cagtacatat 2833741 tgataaaaat caacgattat aacgctaatt tatgatgcat cttatgtttt cttgcacaga 2833801 atatcaggcg taagaaccaa aaagcagcca gcgctccgca ctgactgccc tcatgcttta 2833861 tgattcctgt tttaacttat cattgagcac actttcttct agcacagaaa atgtatcccc 2833921 gtacactctg ttaatatgat tcgctcccca agcacacagc atatctaaaa tcccttctaa 2833981 gctgcggccg tattcgctga gctcgtattc cactttggga ggaacttgat tatatacgat 2834041 tcggttaatg acaccgtccg cttccagctc gcgcagctgc tgagtcagca ttttttgcgt 2834101 gatattgggc attaggcgtt ttaattcact tgtgcgtttt tttccgtgcg tcagatggca 2834161 taaaatgacg catttccatt tcccaccgat cacttcaaga gtcgcttcaa cagaaatgtt 2834221 atattttttc ttctccatac aatccattct cctcacaggc accaaaaagt gactatagca 2834281 cttcaaagta cgtactttta tttcttaacg atatgtttca taatcacatt tgccggctga 2834341 tttgaatctg ctctttttta tttatatagc ttactcggca gaatttcaat catacaacac 2834401 atcttacaaa ggaggaacat catgacttca gccaataaaa gcaatattcc tgcactactg 2834461 gctttggccg taagtgcatt cgcaataggg acaactgaat ttatcagtgt cggccttttg 2834521 ccgctcattg ctgatgacct ggatattccc gtcacgacag caggattgac cgtttccctt 2834581 tatgcgctcg gcgttacatt tggggcacct atattaactt cattgacctc aagcatgtca 2834641 cgtaagacac tattgctttg gatcatgttt atttttattg ccggtaatac gatggcagca 2834701 accgcttcaa gcatcgggat tttactagca gcacgtgtga tatcggcatt ttcgcacggt 2834761 gtgtttatgt cgatcggttc gacaatcgca gcggatattg tcccggagga taaaagggct 2834821 agcgcgattt caattatgtt tactggcctc actgtggcaa ctgtaaccgg agttcctttt 2834881 gggacattta tcggccagca gttcggctgg cgtttcgcct ttatggtcat tatcgccgtc 2834941 ggaatcattg ctttcattac aaatggcatt cttgtaccgt ccaaattacg aaaagggacg 2835001 aaaacaacga tgcgggatca attgaagctt gtgacaaaca gccggttatt gcttttattt 2835061 gtcattacag cgcttggata cggaggaaca ttcgttgtgt tcacgtatct gtctcccctg 2835121 cttcaggaag taacaggctt caaagccggg actgttgcag tgattctgct cggatacgga 2835181 atagctattg ctatcggcaa tatgattggc ggaaagctgt caaaccgaaa tccgattgcc 2835241 gctttattct atatgtttat cgtacaggca atcgttctat tcgtactgac atttacagcc 2835301 ccgtatcaag cagcagggct cattaccatt ctctgtatgg gattgctggc ctttatgaac 2835361 gtgcccggcc ttcaggtgta tgtcgtcatg ctggctgagc gttttgtccc gagtgcagtt 2835421 gacgtcgcat ccgcgatgaa tatcgctgcc tttaatgcag ggatcgcgct tgggtcatac 2835481 cttggcggtg tgatcaccga ttcaatcgga ttgattcata ccgcttggat aggcggatta 2835541 atggtggtcg gtgcagtcat tttaacaggc tggagccgct tgatggaaaa acgagatcgg 2835601 caggaagcct gacaatttta aaggaggaaa taaacatgac aacacattta caagcaaaag 2835661 caacacttca taatggggta gaaatgcctt ggttcggcct cggcgtgttc caagtggaag 2835721 aaggatctga actggtaaac gcagttaaaa ctgccattgt tcacgggtac cgcagtattg 2835781 atactgcagc aatctatgga aatgaagctg gagtcggaga agggattcgg gaaggcattg 2835841 aagaagcagg catttcaaga gaggatctgt ttatcacatc gaaagtatgg aatgcggatt 2835901 taggctacga agaaacactc gccgcgtttg aaacaagtct gtccaaactc ggtctggatt 2835961 atttggatct atacctcatc cactggcctg tagaaggaaa gtataaagaa gcttggagag 2836021 cgcttgaaac gctgtataaa gaaggccgta tcaaagcgat tggcgtaagc aacttccaaa 2836081 ttcaccatct tgaagatctg atgacggcag ctgaaattaa gcctatgatt aaccaagtgg 2836141 aatttcaccc gcgcctcaca caaaaagagt tgataagata ctgccaaaat cagggcatcc 2836201 agatggaggc ttggtcacct ttaatgcagg gacagctgct ggatcaccct gtattggctg 2836261 acatcgctca aacatataat aaatctgtcg cacaaattat tttgcgctgg gatctgcagc 2836321 atggcattat aacgattcct aaatcaacga aggaacaccg cattaaagaa aatgcaagcg 2836381 tatttgactt tgaattaacg caggatgaca tgaaccgaat cgatgcactg aatgaaaact 2836441 tgcgcgtcgg tcctgatccg gacaactttg atttttaatg gccaaaaaac accgttcaat 2836501 atgaacggtg ttttttgtat tatgcccagc tgttcatgat ttcatcaagc tgccttttgg 2836561 tctcttcaag cgtgccgctg ttatcaatga cttgatctgc tcttgctgtt ttttcctcta 2836621 agggcatttg agagcggata cggctgactg cttcttcttc tgtcagctga ttgcgcttca 2836681 tcagacgttc cagttgaagc tcttttgtca cactgaccac aataatttta tcaaccaatg 2836741 attccaattt gctttcgaac aatagcggga tatccaatac aacaaatgcc tcccgatttg 2836801 caacggcttc atcacggcga ttgagcattt cctgcctgac tgcgggatga acaattgcat 2836861 ttaaagcgag acgtttttgt tcatttgtaa ataccagcgc tccaagcttt tttctatcta 2836921 tatcgccatt tgagagcagt atgtcttcac cgaattcgtc aatgatttgc cggtaggccg 2836981 gcatcccttt ttctaccgct tgttttgcaa tgatatctgc atctataact gttattcctt 2837041 tttcaatcag catattggct accgtgcttt tgccgctagc tattcctccc gttaaaccaa 2837101 tgactaaggt caagagatcc actccttttt acaatttcca gagcccaatc gtgattaata 2837161 gaagccccgg caaaaacgcc attttatcga tccatttcca cttagacaga aaatggccgg 2837221 cattgattcc aattgataca aacagcgagc tcatgattgc cacggcgatg ctcatcacaa 2837281 tcggcgaaaa accgagaatg gctgcgccta tacctgctcc aaaggcatca atcgataagg 2837341 caaatcccaa taagaccgcc tcaattccgt tgatcacacc cgatttgtcg atatccgcac 2837401 tcatgggttt tctcaaaata tgaatcacaa ttcctaatga ccgaacctct agattaagca 2837461 gtgttttttc atgcaatagg tattctttat cttttgccgg tttgaaaaat tgatacagaa 2837521 cccacgcacc gattccaacc aatatcaaac cgccaagctt ctccgtcaca tatacaggaa 2837581 aaaacttcgt gagaaagctt ccgatcagca tggatataaa catgacagca ccggaacagc 2837641 aggcgataac caaaatcgct ttaaacggta ttttcatttt tctcaatccg tacgtaaatc 2837701 cgactgaaaa actgtccaag ctgacagcca acgccagcag cagtatagaa accatttgca 2837761 tatccgtttc ttcctttctg ttggtgctct tgtatcagat gtgaaatgcc cgggattcat 2837821 cacaatcata tatatgggaa agtgaaaaat ccgtgtttcg aaaatggcat ccttaatcca 2837881 gagttactga tatatgcacc gacagcttgg acaatgaagc attatgctac ttttttgtct 2837941 ggcactttgc gcaaaaatgc gtgcctcttc ctccaacgac aattttcgaa atcatcgttc 2838001 cgcaattttt gcatggctcg tctttttttc cgtacacaaa atgctgcagc tggaacattc 2838061 cgatttcccc ttgggagttg atatatgaac ggactgtgct tccgcccgca tcaatcgcct 2838121 cctgcagagt gtttttgatt tcagcgtgaa gggttttgat tgttttatct gataattgat 2838181 ttgcttttgt ctcgggatgg acacccgctc tgaaaagagc ctcatccaca taaatgttcc 2838241 cgagtccaac taccgttttt tgatccagta gggcagtttt gacagcgcgg tttgttttcg 2838301 caagccggtc ttttaaatac gcacttgtaa attcttctgc atccggctcc ggccctaact 2838361 gagaaagcgg gagctcgccc gcttcttctc ccggtttaaa taagtgcatg gttccaaatt 2838421 tccgcacatc cctgtaccgg agctgggttc catccgtcat cgtgaatatg acatgcacgt 2838481 gtttatcgtc aggctcctcg gcttgatgaa gaccgtattt tccttccatt cgaaggtgag 2838541 aaaccataac ataatgatct aaatgaaaca gtaaaaactt tccccgtctt ccgatggact 2838601 gtatcgtttc tcctgctagt tttcgcgcaa attcctccgg ttcggcaggc cgtttgatga 2838661 tattcggcca tctgatctct accgatttga ttgtttttcc ctttacaagc ccggtcagag 2838721 tgcgccggac cgtctcaacc tctggtaatt ccggcacatc catcacttcc tatctctgtt 2838781 tatttcgcat cgtaccaaga tgggcctgat gcaaagtcca cctttaacgg cacatctaat 2838841 gcaagcgcat gctccatcac ttcaggaaca agcttttcaa gaatttcaat ttcttccttt 2838901 ggcgcctcaa aaatcaattc atcgtgtact tgaagcagaa gccttgcttt caactgtttt 2838961 tctttcagct tggcagccat gtcaatcatg gcttttttga taatatcagc ggcgcttcct 2839021 tgaatcggcg tattcatggc cgtccgctcc gcaaaacttc ggatattaaa gttccggctc 2839081 gtcagctcag ggatgtagcg gcggcgatgc ataagcgttg ttacgtatcc tttttgtttc 2839141 gcttcctgta ctgaatcttc catgtacgct tttacgcctt ggaagctttc cagatagcgg 2839201 tcgataaatg ctcccgcttc cttccgggta atgccgaggt tctgtgacag accgtaatcg 2839261 ctgatcccgt aaacaatgcc aaagttgacc gctttcgcct ggcgtctcat cgcagatgtc 2839321 acttcatcct tagcgacatg gaacacatcc attgccgttt tcgtgtgaat atccatatca 2839381 ttagtaaaag cttcgatcag attttcatcc tttgaaatat gggcaagcac ccgcagctcg 2839441 atttgtgaat aatcggctgc aaaaatgagc cagtcttttt cagacggcac aaaagcttgg 2839501 cgaattttcc gcccttcctc aagcctgatc ggaatgtttt gcaggttcgg atcagtcgag 2839561 ctgagacggc cagtttgcgt taaggcctgg ttaaatcgcg tgtgcacttt atgcgaatcc 2839621 ggtctcgtca cctttaaaag cccttcgata tatgttgatt gaagcttgcc aatttgtctg 2839681 tactgtaaaa tatagtcgac aatatcatgc ttgtcagcca gcttttcaag cacatcggca 2839741 gacgtagaat agcctgtttt cgttttcttt acgacaggaa ggccgatctt ttcaaataag 2839801 atgacgccta gctgtttcgg agaattgatg ttaaacggct ctcccgcaat ctcatggatt 2839861 ttttcttcat attccttcag cttcgcaccc agttcttcac ccatccgttt taaacggtca 2839921 acatcgacct tgacgccagt tgattccatt tcgccaagaa taagcgcaag aggcatttcc 2839981 agctcttcaa acagttcaag ctggtcgttg ttttccagct cttgaacgag cttttcccga 2840041 aggctttgaa tcgctaacgc ttttcggcca aggtgctcag acagtacgtc ttctgacggc 2840101 actgcccgtt ttgctccttt tccataaact gattcatcac ttgaaacgat atgcaggccg 2840161 taatccttag ccacactcgc aacgtcgtca tatgaattgc ccgggttgat gatataagcc 2840221 gcaaggagcg tatcaaactc ggctcctttc agctcaatgc cctgccagcg caaagcgaca 2840281 acggcccgct tgctgtcgaa gacccatttc ttctgctcgt cattttccac ccattcttta 2840341 aacacctcag actcaacggc aatgtctttc ggaatgaaat aagctcccgt ttcatttacg 2840401 atcgaaaatc cgaggatcgg ctcttcatga taattatcgc caatctgttc aacgacaaat 2840461 gcggatggag aaaccaatat atcgcttgtc acgtctgtga ctgttttgac attaatgtct 2840521 tccaacgatt gatcctgttc tgcttctgca ctgtcttctc caagccgttc aagaagcgtg 2840581 ttgaagccaa gatctttaaa gatggcaatg acctgttcac gattaaagcc ttgatattcc 2840641 aggccggaaa cagatacctc aatcggagca tccgtcataa ttgtcgcaag ctccttgctc 2840701 atcaatgcct gatccttaaa ctcctcaagc ttttccttca atttctttcc gctcacctcg 2840761 tcaatggact ccagcagctt ttcaacggaa tcaaattgtt ttaaaagctt aatcgcagtc 2840821 ttttctccga cgccgggcac acccggaata ttatctgagg aatcgcccat cagacccttc 2840881 atgtcaatga tttgttcagg cgtaagccca tatttctctt tgacatgctc cggtgtgtaa 2840941 aattcaacat cggtaattcc ctttctcgta atggcaactg tcgttttgtc cgttgccagc 2841001 tgggttaaat ccttatctcc tgagaaaacc ttaacttcaa atccgtcttt ttcagccgat 2841061 ttggccagtg tgccgataat atcatccgct tcatattgtt ccagttcata gcggctgatc 2841121 tggtaggcat ccagcagctc gcggataaac ggcatttgtt cggaaagctc aggcggggtt 2841181 ttctgtctgc cgcctttata ttctttaaat gtgccgtgac gaaatgttgt tttcccggca 2841241 tcaaacgcaa ccagcatgtg cgtcggtttt tcatcctcaa gcattttcat caaaatcatc 2841301 gcaaagccgt atacagcatt cgtatgaaca cctttatcat tgcttaacag cggcaatgca 2841361 aaaaacgccc ggtaagccag actgtttccg tctacaagca ctaatttttt tcgttccgtc 2841421 attcaatttc ctcctaagaa gcctcaggct tccattcatc tcttacatag tcattagctc 2841481 ctcttatttt aacaaagttc aatttgaaag gaaaatacgt gaactataag agaagacaca 2841541 aaaaaggacg ggaacacaaa taggttcccg ccgtcaaaat tggctccttg gatgaagggg 2841601 ttctactaca tcctaccagc ataggtttaa cagtgcatga agatattgtt aaacctttgt 2841661 aaacattagg cggacttttc agcggcccgt ttcagcgtca cggtaaagac agttccccgt 2841721 ccaagctcgc ttgtgacatc aattttccct tcatgagcct ctattaaatg cttgacaatc 2841781 gctaggccca gcccggttcc gcccgaattt ctgcttctgt ctttatctac acggtaaaag 2841841 cgttcaaaga tgcgcggaat ttcttctttc tgaattccga ttccagaatc ggcaacctca 2841901 atctgaatgt ctttttctct gggctttaca ttgatagcca cggagccccc ctcaggcgtg 2841961 taggttaatg cattgtttac gagattaaga aatacctgtt tcagcctgta cgggtcacca 2842021 gatacatatt gagggtcttt cgggacattc aggtgcaagg agatgccttt ctcatccgcc 2842081 ttatgcttca gaagcgtttc aatctcacca agcattttgg ccggctcaaa cgtttcgata 2842141 ctgagcgtga aattttgctg ctcgattttt gagagatcga gcaaatcctg aaccaaagac 2842201 tgaagccttt cgctttcctt aagaataata gagagaaatt cagaaagcgc ctctttgtct 2842261 tccatcgccc cgtccaataa cgtctccgta aaccctttta tggacgtaat cggtgttttc 2842321 agctcatgag aaacattggc cacaaaatcc ttcctcatct gctctaattt cttcgtttcc 2842381 gtcatgtcat ggaaaacgag cacaattcct ttccattcat cgtccggccc cataatcgga 2842441 acgccgtcca cttcaaaata acgccgttct attttgatcg gcagtcttaa cagcttgcat 2842501 ttctttgtct ccgtcataaa aatgtcttcg acaagctgga tcacttcttc atgttcaaat 2842561 gcatcgtgat aaagacggcg cagcatatga ttcggattga tatgaaactg cttggcgtaa 2842621 gacctgttta cgagattaat aaagcctctt ccgtcgatca taatcagccc ggagccaatg 2842681 ttttcaatga ctgtcagcag ccgatcccgc tgcatttcct gcgttcgcgt catttccatc 2842741 agatcaatgg caaggctgtt catcgcatgt cctagcttat cagaacgcct aatatagccg 2842801 ccgtacgtcc gtgcatcgta gttgccctta gagagttctg tggctacatt tgtcgctgac 2842861 tcaattgacc ttttataacg tgaggtcatg ctggaataaa aataaacaat gacgataaat 2842921 gcggtacaaa gactggccgt cagcatcccc cacaattcgc cttttaagcc gtcgcttttt 2842981 tcagaggcgg aaagcagcac atatcctgtt ttttcacctt cgcttctaag tgaaagtccg 2843041 taataaagct tgttatctgt tgttgacaga ataccctcat ggccagaaac aagcgcctgc 2843101 accttttggg aatcagccga tctaccgttt gacccataca gcaccttacc gtctgtatcg 2843161 ataacggatg cgctcacatc aagcgcgccg cctgcatctt taatgatttt ctcatttgct 2843221 tgattattca gattgccggc atcaagaagc gaagccaagt attttgcttc tttttcaatg 2843281 tgttcctctg ctttcctttg atcagatgtt tcaaaaagct gctgtaaaaa cagcccgagg 2843341 acacaaaaca ccagaatcat acagacaacg aatacagaaa aaaggcgcac acggtattta 2843401 ttcattcatt tttggctcct ccagtttata ccccaatccc ctaatcgttt taatgtagat 2843461 cggttttttg gtattgtttt caattttgtc gcgaagatgg ctgatgtgca catcaacaat 2843521 tctcgtatct ccggcaaaat cataattcca gactgcgctc agcagcaggt ctcttgtcag 2843581 aactctgcct ttatgtctgc ctaaatagag cagcagttcg aattctttcg gtgtcagttc 2843641 aagctgactt tctttaaagt acgcttcata atgatcaggc aggattttca gatcgccgat 2843701 tacgatctgg ccttccattt catcgttctt catctcacta gagggcgcag ctatttccga 2843761 acgccttaaa atcgctttga ctctcgcatt tacttccctt ggactgaacg gcttggtcat 2843821 ataatcatca gcaccgagct ccagccctaa tactttgtcg aattcctcat ccttcgctgt 2843881 cagcattaaa atgggaaaca tcagtttttg ctgtctcagc tgcttgcata cttcgattcc 2843941 gtccaatttt ggaagcatca catcaagcac aatcaaatca ggtttctctg tttccgcttt 2844001 tttgagtgct tcttccccat ccgaggcggt aatgacatca tagcctgacc gttccaaatt 2844061 gtactgtaaa agagtaacaa tagattcttc atcatccaca actaaaattt tcttgttcat 2844121 gctgtgcctc cagtattata attccccgac atcctatttc tctattttat gtcatcttaa 2844181 catgtttcat gattttattt tagcgaaagc aggacattcc gacaattcgc cttttacatc 2844241 atttttaaaa gaaataaaga cgtttatgat agcgctttca tttatagtaa aaagagaaag 2844301 gctgtattaa gcaagccttt ctctcttttt attaggataa tactttcatg acatttttga 2844361 cagattcaac tgatttattc agctgcgctc tttcatagtc tgtcagttca agttcaatga 2844421 tttgctcaag accgttgccg cctacaattg taggaacacc aaggtagatg ccttcatagc 2844481 cgtattcccc ttcaagataa gcaattgtag gaaggacgcg gcgctgatct ttcaagatcg 2844541 cttcgaccat ttctgtcaga gaagccgcag gcgcataata cgcgcttccg tttccaagaa 2844601 gattcacgat ttcgcctccg ccttttctag tgcgctccac aattgcgtca atccgttctt 2844661 tcggaataag agtttcaagc gggataccgc cagcataaga ataacgcaca agcggaacca 2844721 tatcgtcacc gtgtccgccg agtacgaaac cagtcacatc tttcactgac aggtttaatt 2844781 cctctgccac aaatgttctg aatcttgccg tatcaagcac acctgactgg ccgattacac 2844841 gctctttagg gaagcctgat tctttgtaca ccgcgtatgt cattgcatca acaggatttg 2844901 tcagcaccac aataatagag tcaggagaat atttcacgat ttcctgcgta acgcttctca 2844961 taatcttttc gtttgtagag accagatcat ctctgctcat accaggtttt cttgcgatac 2845021 cggctgtaat gacaacaatg tcagagccgg ctgtatcctc gtaattggat gttcccgtaa 2845081 tttttgcgtc aaagccttga accgggcttg cttcaagcat atcaagcgct tttccctttg 2845141 tcgggttctc caattgcgga atgtcaacaa gaacaacgtc tgccagctct ttttgagcga 2845201 ttaaaaatgc agttgtagct ccggtaaaac ctgctccgat aacagaaact tttttacgag 2845261 tatttcccat gtctctcttc tcctttatgg ctagttttag gctttttcct tgcttagtcc 2845321 atgtttttga tcagttcttc tccgaactct gaacatttca cttcagtcgc cccgtccatt 2845381 aatctggcaa aatcgtaagt tacgacttta gaagcgattg ttttttccat agatttgata 2845441 accaaatcag ccgcttcgtt ccatcctaaa tgctcaagaa gcagaacgcc tgaaagaata 2845501 actgaagatg ggtttacttt atcaaggcct gcatatttag gagccgttcc gtgcgtcgcc 2845561 tcgaaaatcg catgtcctgt ttcgtagttg atgttcgctc caggagcaat gccgattccg 2845621 ccgacttgcg cagcaagagc atcagaaatg taatctccgt tcaagttcat tgtcgcaacg 2845681 acatcaaact cgtttggacg cgttaagatc tgctgaagga aaatgtcagc aatgctgtct 2845741 ttgataatga tttttcctgc tgcttccgct tcgctttgcg ctttgttggc agcgtctttt 2845801 ccttgttctt cagcaatgcg gtcatattga gcccatgtga agactttatc tccgtattct 2845861 ttttcagcaa gttcatagcc ccagtttttg aaggcgcctt ctgtgaactt catgatgttt 2845921 cctttgtgaa caagtgttac agatttgcgg ccatgctcga tcgcataatc aatggcagct 2845981 ctgaccaagc ggcttgttcc ttcttctgaa acaggcttaa tgccgatacc tgatgtctca 2846041 gggaaacgga ttttattgac gtttaactca ttttgaagga agctgataag cttttgcact 2846101 tcttcagagc cttttgcata ctcgatgcct gcgtaaatat cttctgtatt ttcacggaag 2846161 atgaccatat cagtatcttc agggcgtttt accggtgacg gcactccagt aaagtatctt 2846221 acaggtctta agcagacgaa taggtcaagc tcttgtctga gcgctacgtt caaagaacgg 2846281 ataccgccgc cgacaggtgt cgttaacggg cctttaatcg cgatgaaata ttcgcggatc 2846341 acatctaatg tttcagcagg gagccactca cctgttttat tataagcctt ttctccggcg 2846401 taaacttctt tccatgtaat tttcttttcg cctttgtatg ctttttctac tgctgcttcc 2846461 aaaaccttcg aagccgcgtt ccaaatatca ggaccggttc cgtctccttc gataaatggg 2846521 ataatcgggt tgtttggtac gtttaatact ccgttagaga ctgtaatttt ttcaccttgt 2846581 gccacaataa aaacctccca gtatgtaatt catatttaga aaacatttta tttttcttat 2846641 atagaaaata aaatgatttt tcctaacatt caatttaaag tgtaacccaa ttttgatgtc 2846701 tgaacaagag gctaacctca ttgacgcaag ccagcctcca atggttcttt aggctctttc 2846761 ttcaatcgga acgaattttt gtttgtcagg gcctgtgtaa tctgcccgcg ggcggatcag 2846821 acggttgttg tcatactgct caagaatatg agcgagccag ccggacattc tgcttacagc 2846881 aaaaatcggt gtaaacaaat catggtcaat accgaggctg tgatatacag aagccgaata 2846941 gaaatcaacg ttaggcggaa gctttttctc tgatgtgacg atgtcttcta tacgaatcga 2847001 catctcatac catttgcttt cgcctgtcag gttggtcagg cgcttgctca tttctttcag 2847061 atgcttcgcg cgcggatcac catgcttata cacacggtgg ccgaatccca tgattttttc 2847121 tttcttttca agtttagcgc ggatgtacgg ctcagcgttt tccacttcac cgatttctgt 2847181 cagcattttc ataacgcctt cattcgctcc gccgtgaaga ggccctttca gcgcgccgat 2847241 tgctgcagta atgcctgaat agatgtcaga aagtgttgcg acgcagaccc tcgctgtgaa 2847301 cgttgacgcg ttcagctcat ggtcagcatg taaaatcaat gctttgttga aggcttcaac 2847361 ttcaattggt gaaggctctt caccgtttaa tgtgtaaaga aaattctccg caataccgta 2847421 atcttctctc ggttcaacag gctcaagacc cttgcgaatt ctggaaaacg ctgcaaccag 2847481 gccaggcacc tttgcctgaa ggcggatcgc ctttctgtag ttggcttccg ggttcatggt 2847541 atcagcctcg ctgtcaagca ggcctagtaa tgaaattgct gtccgaagag cagccatggg 2847601 atgaacattt tcgagggaat aagatttgaa gtgctcaata atttcttgcg gaacggcagc 2847661 ttcctttgca agctgctgct ttaactcttc aagctctttt ttgtttggca gccttagatg 2847721 ccaaagcaag tagatgattt cttcaaaact tgcattctct gtcaaatcat cgatatcata 2847781 ccccacatat gtaagggtat catcaataat agaactaaca gatgatgttg ttgctacaac 2847841 cccttcaaga ccgcgtgtcg ctgtcatata taacatctcc ttttcaataa atttcccctt 2847901 taagagtgtt gtaaaaacat gaggcttact taaaaagcac gatgcaagta tttctctccc 2847961 ccaaaaagaa aatgcttaca ttttactggc tgctggaact aaaacccttt gcttttgaaa 2848021 gaacataaca aatttttata agcttattta agtttaagcc tattctcatt ataaacaata 2848081 atcagacatt tgttaaatgt ttacctataa tttttttttt ccattctgtg atttccccga 2848141 aaaaacgcct ttatttgcgg gtttttgcat aaaaaaaagc ggctttaagg ccgctttttt 2848201 ttatgaagtg aacagtttta cgatctgcat ggctaaataa gcaatccccg ctccgatcag 2848261 cggccccacc gcaactcctc caaaaagcgc gactgcaaga atggtcccga tcacgagagc 2848321 agttgtaata tgcggatcat tttcaagcag ggtcaggccg ttttttgcaa tcagcgccac 2848381 tgcgatcccc gctccaaggg cgatccatgc gtaggaagac cgcattgctt ctccaagctg 2848441 cttaaatccg atttctcccg tggcaatcgg gacaagaacg gcgatggtaa taatggtcac 2848501 accccagtta atgccttttg actggatggt cggaaataat ttctgatcaa gcccaacgat 2848561 tttgatgatc aaaaggacgg atacagcaaa gagcaatgat tggttttttg cgataagtgc 2848621 gatagccaag agtaaaatta aaaataaatt cgcttgtgta aacacatgcc atccctcctt 2848681 taagatgaat gtattcatat tcagccgcag cgtgaataca tataaaaaat aggacatgct 2848741 gacgagagga ggaccgtttt tgtgaatcaa tcttatatca ctattttttt cagaaccctc 2848801 tttgtcatat caatgaccgc agggtcgata gctgcggcct attattcgtt tccgttaact 2848861 tatccgttcc tgatcgccct tattctatct tcagtgattc atcctgttgt cgattatttg 2848921 gacaaagtga caggattccc ccgaacgata aatgttctgg gcgttcttgc tttttttctg 2848981 ctcgcagcct tcggcgtgct caccattctg gtagccgaaa tcgtaacggg aacagcctat 2849041 ctagcaaaaa cgctgcctcc gcatatcagc acgtttattt catattgcga aaaattgttt 2849101 accactcata ttcagccgct ctataacgag ttaactcttt tgtttcaaga attggaaacg 2849161 aaccagcagg cttccatcgt cactcatatc cagacactcg gtgattctgc cgctaaaaat 2849221 gccgggctcc tgctgtccca cattctagag atgatcccga gatttttcgc tcttcttccc 2849281 aatacggcgg cggttctgat tttttctctt ctggcaacct tttttatgac aaaggattgg 2849341 cataagctga aagccatgct tgttttaatt ctgccggatc gtgtgacagc taacagcaaa 2849401 gcaatcagca gcgaattaaa aaaagcaatg actggtttta tcaaagcaca agccgtcctc 2849461 gttttcatca cgatggtgat tgtatttatc ggcctttctc tcttaaaggt tgaacacgcc 2849521 gcaacaattg cttttttaat cgggcttgta gatcttctcc cttacttagg tgccggctcc 2849581 gtatttgtgc cctggatttt gtatttatcg attacgggcc agctgcccca agcaatcgga 2849641 attggtatcc tgtacctcgt cgttcttatt cagcggcagc tgacagagcc caagatacta 2849701 agtaaatcta tcgggatcga tccgctggca acactcatcg ccctgtttgc cggctttaaa 2849761 ttattcgggt ttttaggact gattgcggga ccggctgtac tcgtcatcat ccaagctttc 2849821 atcacaacag gcgcattaaa agaaatatgg tcctatatca ccgttcagca aaaataaaac 2849881 ggcagccgtt ttttcatggc tgccgttttt tatttgatga tgatccgctt attcttcgac 2849941 attcctctca gccatttgaa cagaatcggc ttacaccagc cgcgggtaaa cgggataaga 2850001 agacaggcgc cggccaaatc tgataaaaag cccggaagca tcagcaatag accgccaatg 2850061 aaaatgcaca gaccgtcagc aatcgcttct cccggcattt tgccatattg aagatcacgc 2850121 tgaaccttat aatacacttc ggttccttgt ttttttgcag ctgctgcgcc gataatgcca 2850181 gtcagaatca tgaatagaac tgtcggcaaa ataccaatca gatttcctaa aaataggaat 2850241 ataccgattt ctattgccgg aaacacaata aaaagcaaaa acaaaaatct catatccaag 2850301 ccccccacac gtgtaacacg ttctgttcaa caaaaggcat gataaagaga aaaggaaggg 2850361 attccccttc cattttcacc tgtaattaaa gaacgctcgc acggccttga tagactgcgc 2850421 ctctggaagc gtcaactgta atatcctggc catctgtcaa aatagatgtc gcattttcca 2850481 gacccacgat aaccgggatg ccaaggctta atccgactac cgcagcatgg ctagtcaaac 2850541 cgccttcttc tgtaataaga gcagacgctt tttcaaggga tgcaatcata tcacggtcag 2850601 tgcttttggt aacaagtacc gcaccgtcag tcattttttg ctcagcttct tttgcatttt 2850661 gtgcaacgac aaccggaccg taagctgatt tgcgtccaat gccttggcct ttagcgatga 2850721 tatcgccgac agtatgaacc ttcattaagt tcgtagtgcc ggactcaccg acagtgccag 2850781 ctgtaataac gataagatcg ccgtgtttta caattccgct gttcaatgat ttttggacag 2850841 catcctcaag catctcatct gttgagctcg cattttggcc gctttccgcg aatacgccag 2850901 atacgagggc aagctttctg gaaatagagt catttacagt aaccgcaaca atcggagcct 2850961 gcggacggta ttttgcaatc atacgtgctg tatggccgct ttctgtcggc gttacgatcg 2851021 cagcagcatt caggttaatc gccgtatgtg cgacagattg tccaattgcg tctgtaattg 2851081 tcatgcccac ttggtctctg cgttttgaga gaatttcttt ataatttaat gcttcttcag 2851141 aacgggacgc gatgttatgc attgtttgaa ctgcttcaac cgggtaactt ccggcagcag 2851201 tttcaccaga aagcatgatc gcatctgttc cgtcgaagat cgcgtttgca acgtcacttg 2851261 cttccgcacg agtcggacgc gggttgcgct gcatgctgtc aagcatttgt gtcgctgtaa 2851321 taacaggttt gcccagcgcg ttgcattttt tgatcagttc tttttgcaca agcggcactt 2851381 cttcagctgg aatttccaca cctaagtctc cgcgtgcaac cattaagccg tcagacactt 2851441 cgagaatcgc atcgatgttg tcaacgccct cttggttttc gattttaggg atgatttgaa 2851501 tatcctgagc gttgtgctct tcaagaagct cacggatttc gagcacatcc gtagaacgtc 2851561 gaatgaaaga tggtgcgatg aagtctactc cttgctcaat accgaaaacg atgtctcgcg 2851621 catccttttc agtaatcccc ggaagattga cacttacgcc cggtacgtta acaccttttt 2851681 tatttttgag tgttccgttg tttaatactt ttgttttgat ttcgcgttta gcggcatcta 2851741 catcaagtac ctcaagaccg ataaggccgt catctaacag aatcgttgaa ccttgttcaa 2851801 cgtcatggac taaaccttca tatgtcactg aaattttatc tgttgttcct acaacctcgt 2851861 ccattgaaat aatgagctct ttgcctgttt caagctcaat accgccgttt tccattgtat 2851921 gtgtgcggat ttcaggacct tttgtatcaa gcagaattcc aacgttcttg ccaagttttt 2851981 tacttgcttc gcggatattt ttaattcttg caccgtgctc ctcaaaatct ccgtgagaaa 2852041 agtttaatcg agccacgttc attcctgact ccattaattt cgtaagcatt tcaatacttt 2852101 cacttgccgg accgatggta caaacaattt tagtttttct catttggttc acttccttct 2852161 gaaatcttca gccttcagct gtacattaga tagacagttc ttttgaaagc tgatacatgt 2852221 tttgctcaac tgtgtgtttt gtctcaagta tttctataat atcatggtct acaagcttat 2852281 tgttttgtat acctacacag cgtccgcctt ttccttcaag cagcagttca actgcatatg 2852341 cgccgagacg gcttgccaac acacggtcag cagcactcgg agaacctccg cgctggatat 2852401 ggcccaatac agatacccta gtttcaagat ttgtttcttc ttcaatgcgt ttcccgaatt 2852461 caacaccgct gcctacacct tcggcaacaa taataatact gtgcttcttg ccgcgttcgt 2852521 ggccgcgttt taagcgggca atgatttcgt gcatgtcata gtctgcctca gggattaaga 2852581 tcgattctgc gccccctgca agaccggccc acaatgcgat atcgccggca tgacggccca 2852641 ttacttcgat tacatatgta cgttcatgag aagtcgctgt atcgcgaatc ttatcaattg 2852701 cgtcaattac tgtatttaaa gctgtatcga aaccgattgt aaaatcagtg cccggaatgt 2852761 cattatcaat tgtacccggt acacctacac atggaaaccc gtgttccgtt aattttttcg 2852821 cacccatata ggaaccgtct ccaccgataa caacaaggcc ttcaatacca agcttcttca 2852881 agtttgctat ccctttttca cggccttcaa ctgttttgaa ttcaggacat ctcgccgtat 2852941 aaagcttagt ccctccacga tgtataatat cgcctactga tccgagttca agcttttcaa 2853001 tctttccgct gatcaatccc gcgtatccgt tgtaaatacc gtaaacttca acgtcatgat 2853061 agatcgcttt tctgactact gcgcgaactg ctgcgttcat tcccggggaa tccccgccgc 2853121 tcgttaatac ccctattcgt ttcattctcc attcacctca gcaacatata tgattaaaca 2853181 taacatgatc attgccctaa aaacaatgaa aagggatctc catcctccct atgaaacctt 2853241 acctattata caattaaata aattgttttt aaataaaatt taaggaatgt cacaaaaaat 2853301 aaacgtgagc caaaggcttc acgtttattt agtttacccc gatatattga tcttcaaccg 2853361 agactttgcc aattgcttta tatttttcat aacgctgctg aactaattct tcttcgctca 2853421 gcttcagtaa agtttttaac gattgtttaa gggtttcgtc catatagctt gcctgcagct 2853481 tcacatcatg gtgcgctccg ccttttactt ctttaatcat atgatctata atacctaatt 2853541 cttttaaatc cggcgcagtg attttcattg tttctgctgc ttttttagca agactggagt 2853601 ccttccataa aagtgccgcg gcaccttccg gagaaataac agaataagta gagttttcca 2853661 gcatatgcaa gtgattgcct acacccagac caagggctcc gccgcttccg ccttcaccaa 2853721 tgacgatgca gataacaggc actcgaaggc cggccatctc aaacaggttt ttggcaatag 2853781 cttcactttg tcctctttct tcagctgctc gtccagggta tgcccccttc gtatcaataa 2853841 aacagataat tggtctgtta aatttgtcag cctgtttcat cagacgaagc gcttttctgt 2853901 agccttctgg atgcggcatc ccaaaattgc ggactaggtt ttccttcgtg tctttgccgc 2853961 gctgatgccc gattaccgtt acagggaggc cgtggaactt cgcaatcccg ccgacaatgg 2854021 cttcatcgtc cccgtacgct ctgtctccgt gacattcaaa aaagtcggta aacaggtgtt 2854081 cgatataatc aagagttgtc ggacggtccg ccagacgcgc gatttgaacc cggtcccacg 2854141 gcttcaaatt tttgtaaata tcatcctgaa gcttagcgag acggtcttcg agccgttcga 2854201 tttccgcact tagatccata tcggaatctt gggtgaattt ttttagttcg gcgattttgg 2854261 tttgcagttc aatcaccggt ttttcaaatt ctaatcttgg agccactcaa tgtcacctcc 2854321 tgtttgatgc atatccagca gattttctaa cgtttttttc atatcgtcgc gatgaataac 2854381 cgcatcaagc tgtccatgtt ttaataaaaa ctcagccgtt tggaagtcct caggcagttt 2854441 ttctcctatt gtctgttcaa taatccgtct tccggcaaaa ccgatcagcg cgccaggctc 2854501 agcgaaattg taatcgccaa gggatgcaaa gcttgctgat acgcccccgg tagtcggatg 2854561 cgtcattact gaaataataa gaccctgttc ttcactgaac agttttaacg cagagcttgt 2854621 ctttgccatc tgcatcaaac ttaatacgcc ttcctgcatt ctagcaccgc ctgaagccgt 2854681 aaaaataata aacggaactt tatcagcttt tgctttttca atcgcaagcg tgattttttc 2854741 accgacgact gaacccatgc tgcccattct gaatgaagag tccatgacgg cgacaacagc 2854801 cgggtgtccg ccgatggtgc ccttgcctgt cacaacagcc tcgtttaagg atgttttctc 2854861 gcgatctttt tcaagctttt ccagatatcc cgggaaacca agcggatttt ccgagagcat 2854921 tccctgatta aattcctcaa aggattgttc atccatcaag ctttcgatac gctgttttgc 2854981 gttcattggg aaatgataat cgcagttcat gcatacccgc atatttttat ccaactcttt 2855041 agtgagcatg atttttttac acttaggaca ttttgtcata atgccttccg gaacatcgtg 2855101 cttcgcttga tcagacggta cggaagcata ctttttcttt ttcgtgaata tatcctttaa 2855161 caaatgatta cctccctttt gtgaagggtt ctcttcaccg catgtcatca aacagataga 2855221 cttgctaata actttaccga aactattgta ctttttttgt caaacgctgt catcctcaat 2855281 tcgacaactt tttattcgat gacgtgctcg gaaaggcttg tatgaaatca gataaggtgt 2855341 tgaaacgaca aggttgacag cgcattcaaa aataatgtta aacccggctg aaattttttt 2855401 aaggctaacc ccctaaaaaa atttcagccg tcagtttaac ttgagaacag cgcgccggtc 2855461 tccgccaacg cgctgccatt tttggaatga attaaaatta ttcaccaata atcgtaagtt 2855521 ttcttgtttt ttctgcgact tcctcagggt caacagtgat tcttgcaaca cctgtttcca 2855581 tcgcagcttt tgccacagcc ttcgcaacag caggcgcaac acgtttatca aacggtgcag 2855641 ggatgacata gtctgcgcta agctcatctt ctgaaaccag tgaagcaatg gcttcaaccg 2855701 ctgcgatttt catttcctcg ttaatatgag tggcacgcac atcaagcgct ccgcggaaaa 2855761 taccagggaa tgcaagaaca ttgtttactt ggttcgggaa gtcagaacgg ccagttccga 2855821 caacgcttgc tccggcttca cgcgcatctt ccggcatgat ttccggattt ggatttgcca 2855881 ttgcaaagat aatcggatct tttgccatgc tttgaaccat ttcttttgtt aacgcgcctg 2855941 ctacagagac accgataaat acgtcagcat caacgataac atctttcaga gaaccgtctt 2856001 tgcgatcttg gttcgtgaac ttcgccactt catttttgac atcgttcatg ccgttcgggc 2856061 gcccttcata aatggcccct ttggaatcgc acatcacaat gtcgcgaacg ccataatgat 2856121 gaagaagctt gataatcgca atgccagccg cacccgcgcc gtttgcgaca actttaatgg 2856181 atgacatgga ttttccagac agtttcagcg cgttcacaag acctgctacg gttacaatgg 2856241 cagtaccgtg ctgatcatca tggaaaaccg ggatgtttgt ttcttttttg aggcgctctt 2856301 caatgataaa gcagtttggc gctgcaatat cttcaaggtt gacgccgcca aatgtcggtt 2856361 ccagcaattt tacagtttca acgattttat caacatcgtt tgtgtttaaa gcaatcggga 2856421 acgcatctac gcccgcaaag cttttgaaaa gaactgcttt cccttccata acaggaagcg 2856481 ccgcttcagg gccgatgttt ccaaggccaa gcacagctgt accgtcagtt acaactgcta 2856541 ccatgttccc cttcattgta taatcatata ctttgttaat gtcttcatga atatccttac 2856601 acggttctgc aacacccgga gaatacgcga ggcttaaatc tttcgcattt ctgacctcta 2856661 cttttgattt agactccagt ttcccctggt tgactttatg caggtgtaat gcttcttctc 2856721 ttaatgacat tctcctaaac actccttatg gatatttttt gattcgtata ctgctgcgtt 2856781 gattgctgca ttctgcggag taaatctatc tgaatattta aacaggatca cataattgct 2856841 ccaattgtat aacaaaaagc gaatcgttac cactgtttta aaacgacgtt tttttgaccc 2856901 aacagctctt ttaagcgata taacacctgg tgatctgcat tgatatggaa cgactcaggt 2856961 agcttaatcg tctgtttttg cctttcataa tagagataaa cgcctgtttc ccctttatgc 2857021 tccagcaaaa tgcgcttaat ctttgccagg atctcctggc tgtgctgact gctttctatt 2857081 tttatataaa ccgatggcgc tttttctgca tccatatctt ctaataattc tgcccgggac 2857141 atgatgaatt ggatcttatc ttgtctaact tcacatttcc ccgcagtgaa caaaagagcg 2857201 ccttctctta aaacgggaga aagctgtctg aattgttcag ggaagactac ggcttccatc 2857261 tcgccggttt catcactgag cgttaaaaac gccatgtttt gacctgtttt cgtccgaatc 2857321 gttttgatct tcgacagcag aacgcctagt gaaagctgcc ttttgactgc ccgctgagcc 2857381 tgcagaatgg agactgctcc ttgcgcagtg agctgttttc ggaaggcgga gaggggatga 2857441 tttgaaaaat aaatgccaag cgtttccttt tcaaacgcaa gtaaatccac cagaggaagc 2857501 tcctccgtct ccacatactt cggcttaatt gaaaacgatt catctaaaaa caatcccatt 2857561 tggtcatcgt ccgcggcgaa tagctcagca tgttccaaag caacatcaat ggatgcgagc 2857621 agcgtggccc ggttttggcc gaattcgtcc atcgcaccag aaaagataag tgcttcaagc 2857681 attttgcgat ttacgctttt tgacggcacg cgaaagcaga aatcgaaaag atcttcaaat 2857741 ggtttctctt ttcttgcttt atatatatct ttgactgctg agacgcctac actttttatc 2857801 gcgcggaggc tgtatctgac agatccgttt tcaactgtaa acggaaaact gcttttattc 2857861 actgacggag gaaggatacg aatcccgctc ccctttgctt cgtaaagata ttgagagatt 2857921 ttatcctcat tgccaatgac gcttgtcagc aatccgcaca taaaatataa cggataatga 2857981 gctttcaaat acgcaagctg gcacccgatc atgctgtatg ccaccgcatg gcttctgtta 2858041 aagccatagt ttgcgaattt gacgattaaa tcgtagacct catttgcagt gtctacagaa 2858101 tactcctttt ttaagcaccc ttcaacaaaa tggcttcgct ctctgtccag gatttctttt 2858161 ttctttttgc tgaccgccct tctcaatagg tccgcttcgc ctaaagaaaa ccccgccata 2858221 cgggaagcaa tcatcataat ttgttcctga tacacaatga cgccatatgt atcttccaaa 2858281 atgctcctta aatcttcatg aggatagtga acaggcgccc gaccgtgttt acggtcgata 2858341 aataacggaa tattttccat cggacccggc cggtacagtg cattgaccgc cacaatatct 2858401 tctaggcccg aaggtttcag ccgtttcaag acgcttctca tccctgcaga ttcaagctgg 2858461 aaaatgcctg tcgtatcccc ttttgacagc aaggagaacg ttttgtcatc gctgtaggaa 2858521 atacttgaaa ggtctatttt aatattttct tctttttcaa tcattgaagt gatggattca 2858581 ataagtgtca gattcctcaa acctaagaaa tccattttta aaaggcccaa gtcttcaaga 2858641 tggtccatcg cgtattgcgt taaatagatc ccttcatgcc cttcttgaag cggaacaaca 2858701 tctgttaacg gttcttcact caggacaacg cccgctgcgt gggttgatgc atgccttggc 2858761 agcccttcta ttttccgggc aattgaatag acttgctgaa gcaggcttga ctcccgaagc 2858821 cgcttatcca gctgcggtga ctgctgtctc gcttcatcca gcgtcattcc cggtcttgaa 2858881 ggaatgagtt ttgcaagctg atctgcctcc ttcgggctga cgccgaatac tctgccgacg 2858941 tcccggagcg ccgcctttgc cgcaagtgtt ccaaaggtga taatctgtgc gacgtgcatt 2859001 gcaccgtatt tctgctgaac atattgaatg acttcatccc ttctagtatc gggaaagtca 2859061 atatcaatat ccggcatgct gacgcgttcg ggatttaaaa atctttcaaa cagaaggtga 2859121 tgcttaatcg ggtcaacatc tgtgatatac agcacatatg ccacaagaga acccgccgca 2859181 gaaccccttc ccggtcctgt aacaatccct ttttcatggg cgtgcttcat aaaatcccac 2859241 acgatcagaa agtaatcgct gaacttcatc cgcttgatga catcaagctc atattgaaga 2859301 cggcgaaggt atcgttcatc aggcttgccg aaacggctgc ggagtccctc catacagata 2859361 tccgttaaat aatcatcagc ggacgttccg tctggggtcg gaaaagacgg tagacgggtc 2859421 tgcccgagac tgacgtcaac ccggcattgt tccgcgatct ctacagaagc ttgcagtgcc 2859481 tcgggatgct ctcgataaat gttttgcatt tcttcgagtg gtttcaaatc gagatcaggc 2859541 aaatcttcag cgggtgcatc cgtcagtttt tcccccgctt taatcgcttt caaacaacgg 2859601 taggcagcct tatcttcctt ccttatgtaa tgcacatcgc ctgtggccgt aacagggata 2859661 cccgtttctt ctgacagctt tagaatctgc tcagacaaga cttgattccc tttaaaaggc 2859721 tgataggaga aataaaaagc tccctttccg aatatagact gaaattccag cgaggcttga 2859781 gcagcctgtt cgaacagccc tccttcaaga agcgtttcaa tatatccttt ttcgccgggc 2859841 gttattgcga taatcccttc tcgataactg tgaagccatt tcggcttcag tccgcctttt 2859901 gatttagatt gcagaacgct gctgattttc agcaggtttt gatagcctgt attcgatttt 2859961 gccagcagga cgagcgggta tgcttcaagc tcgctgtcat ctgtaaaaac agaagccgtc 2860021 aaaccgatta ttgggttgat ccctctcgcc ttgcaagctt tataaaattg aatagctccg 2860081 tacatgacat gatcatctgt cagcgccaaa gacgcatatc cgagcctgtc agcttcactg 2860141 acgagttctt ccacagccgc ggcgctgttt agcaggctat acccgctatg cacttgcagg 2860201 tgaacaaaag acatgctatc acctctttct cattacgatc catttcttcc ttcattataa 2860261 ggccggtttc caaaagaaac aaatgttctt ttttgactca tcatcatact tgtcctgaaa 2860321 gctcaatatg atataaaagg tgaggtgata aagatggatc aggaagcagg atttatggtg 2860381 aattttatca atagctactt cattgcgtta ggggtgctga tcgggggcgc actcatcgga 2860441 gggctcggag catacttggc aggcgaaccc ccgcttacag ccattacaaa gcttgccaac 2860501 cggttaaaaa tatgggcgct tgtcgcagct atcggaggca cctttgatgc ggtatacagc 2860561 tttgaacgcg gcatactcga aggcaatacg agagatatct ttaaacagct tcttttaatt 2860621 atttcggcca tggggggcgc gcaaagcggc tggcttatta tatcatggct gacccaggag 2860681 catctttctt catgagggtc ccccagcatt acaaaaaacc gggatggcag cgttttttcg 2860741 cgggaatgat gtgcggagcc gtaatcagct ggttcttttt cctgtttact tacggaacat 2860801 tccaagagga gcaggtcagc ctcatcgaaa agcaaaaaga gcatgtaaaa gacttgaaca 2860861 atcaaatttc gatctatcag gaagacctcc ataaactgaa tgaagataat aaaagaaaac 2860921 tgctgattca aagcgtcagc gtcaaattgc tgaatgggga taaatataaa atatcacagc 2860981 cggataaaac gaaattcgag gagcatgtaa aggatgatat ttcagaggtg attacaaaag 2861041 acatagagag cgtctatcaa acaaaggatc tcttgaagcg gacaattgaa aataaagtct 2861101 atatgatcaa tgaaaaaaaa tacgaggcaa ccgtcagaga attgattatt tatacgaggc 2861161 tgacagtgga acttgaaatt tctttcgcca cataattatg gatttttttt aaattctcca 2861221 aacttctgtc gctttttccc attctttttt ataaactata tgtgaggctt aatggcgaaa 2861281 ggaaggagga agggaaatgg aggtttacag tgaccgtcag ttagcaaaag atcaagcagc 2861341 ccgtctcaga caaggttttt ctgcatatgc cgaaacaaac tcactcgctt ccctcatcaa 2861401 aaaagaactt caatcacaca atctccaagt ctacgaggac cttactgatt tcggctgctg 2861461 gttcatcccc gtcacagatg aacactaaga gagagggtct cccctctact cgtgttcttt 2861521 acataatgtt tccagatcag ctaaaatacg atcagcttca tcccagctgt aaatagaggc 2861581 gcctgaagct aacggatgcc ctccgccgtt atatttccgg gcaagtccgt taatgacagg 2861641 ccccttcgaa cggaatctga ctctgatttg atcgtcttct tctacgaaaa acacccaggc 2861701 gcgaatacct gagatattgc caagcgtccc gacaagctgc gacgcttcag aagccgttgt 2861761 gccgaatttt tcaagcgtat cctttttgat gaaaacagaa gccgccccgt tttcggacaa 2861821 agacacattt tgaaagataa agccgttaag cttcaccaca ttcagttttg tttcatacaa 2861881 ttgattaaat aactctgagg aagagaatgg atactgaatg agctcgcctg catattttag 2861941 tgttttttcc gtggtattcg gaaataaaaa gcgtccggta tctccaacaa tgccggcgta 2862001 gatcagctct gccgctttcg tattcagctt ccagccgtgc tcttttcctt ctaaatacag 2862061 ctcgtaaatc atttcactta ctgagctggc gcttgtatcg acccagagaa ggtcaccgta 2862121 tggatcttcg ttcggatggt ggtcgatttt cattagtttg gcgcctgaag gataacgctg 2862181 atcgtcgatt ctttcctgat ttgccgtatc gcagacaatg acaagtgcgc cttcatatgt 2862241 ttcattgtcc acctcatcaa gggaatataa gaaagagagg gacggttcag gcgtgccgac 2862301 cgcaaaaata tttttttcag gatatgtttc acgcaggatt tccgtaagcc cacactgtga 2862361 tccgtaggca tccggatcag gacgcacatg tctatgtaag ataatcgtgt catataatga 2862421 tatggttctg atcaattctg ttttcatttg atactccttt attgttttta ttcattaaat 2862481 cacattctct gccgacggaa aagaaaaata acgtcaaaac caagcccgtt tttgtataaa 2862541 atggggttgt aaacttttac gatggaggat ttcatttatg ctggttcttg tttttttgat 2862601 tgggctttca gcctgctttt atgtgtacta taaagtaaaa ggcgtacggg caaagccatc 2862661 tttggcaaaa gaaatatgtt cagcaaaatc aagcatggcc ttagggtcac tagtcctgtt 2862721 ctacgggctt aaccaaatga tattattcca ttcagtatta acgttagtaa tcggcggtat 2862781 ctttatcgtc ataggagcag gaagcgcttg ggcaggttat aaagccttca ggcattacaa 2862841 tccccttcac gccaaagaag ctgaaagaga tcacgcgtaa ggggcgcctg aacgtccctt 2862901 agcttctttc catcagctga accatcagca tcgctttaga cacgatatga ccttggctgt 2862961 gcacttccac ttccattttc ccaaactttc tgccggcctc caagatgcga ggtttgactt 2863021 cgatgactga ttccatctgc acaggcttca aaaagaagat ggtgatgctc tctatgacga 2863081 gttcgccgcg ttttttcgag cgcaaaaatc ggtttgccgc ttgcgtcaaa atggtcgtaa 2863141 atacgccata agaaatggtt ccaagctgat ttgtcatttg cggcgtgact tcatactcgt 2863201 aaaccgtttg atcttcttta tcatcaccct catctttaaa cccccttgaa acgatatcat 2863261 caagcttctc cccgacctgc ggctgctttt gaatcatttg aagagctttc aatacgtctt 2863321 ggcggctgat catgccgatg agtttttggt ggccgtcagt gacgggaagc acttcgatcc 2863381 cttcccatac catcatttgc gcagctgaag cgacagatgt tttcccaata accgtgacgg 2863441 gatttttggt catgactttt tctatagatg catttcggtc atggccagca atatcttttg 2863501 atgtcagaat gccatggatt ttcatttgat cgtcgacaac cgggaagcgg ccgtgccccg 2863561 tttcaaaatt tttctcatac catttttcaa gtttatcctt aggcgaaaga tataccgtgc 2863621 ggtcagcagg tgttaggatg tcctccacca aaacaatttc ttttttgatc agctggtcat 2863681 atattgcccg gttaatcatc gcggcaactg taaaggtgtc atagctcgtg gataaaatcg 2863741 gcagttcaag ctcatctgcc agctgcacaa tgctgtcatc cgtgttaaag cccccggtca 2863801 ccaatacggc cgcgcccgct tcaagcgcct gcctgtgtgc attgattctg tttccgacaa 2863861 tcaaaagatt ccccgctgcg gtgtaacgca tcatcgcgtc aagctccatc gcgccgatga 2863921 cgaatttatt caatgtctta tggagccctg ccctgcctcc gagcacttgt ccgtctataa 2863981 catttacaac ctctgcatag gtaagctttt caatgttctc ttttttcttt tgttcaattc 2864041 tgattgtgcc cacacgttca atcgtgctga caaacccttt attctctgct tccttgatcg 2864101 ctctgtacgc ggttccttcg cttactttca tttcctttgc aattcttcgg acagaaattt 2864161 tttcaccgac aggcagtgaa tcgatatacg ttaaaatttg ttcatgcttc gttgccaagc 2864221 ctttcacctc taaggacagt cttcttgttt ttattataag gtttcaaagg atttatacgc 2864281 aatgaggctg gaaaataaaa aagaagcccg accggcttct tacagcgttg atttcgttcc 2864341 agtcaaacgc aaggaccacg tgattccttt tacatcgtaa agcggaaaaa cctttatttt 2864401 tcttttaaat ggacatcaac cgctgtctta acaatatttc gattccctat tttagataaa 2864461 acaaataaaa ctgcggatag ccatatcgcc cctatggccg tatagatcaa tggatgaaca 2864521 gctgtgtttg cgatccattc atttattaat gttctggcat ttaccagaat aataaatcct 2864581 cctacaagca cacccatcaa ttgcggatga aacttctgca ccagccatgc tgcgataggg 2864641 gcagcgataa ttccgccggc cattagtgaa aacacccata accaattgac gtcctcccat 2864701 cctaatgaaa taagaaaacc ggcggttgca gatacggcga tggcaaattc acttgtgtct 2864761 acagtcccga caactttcct cgggctcaag cctttgcggg ataataaaat cggagtggtc 2864821 accggtcccc agccgcctcc gcctgtggca tctgcaaaac cagcgatcac tcccaatggg 2864881 atggattgtt ttcggtttaa cggcacatgc ttcttctcaa gagccggctt atattgaaat 2864941 aaaaacctga tcaatacata tccgcccaga aggagcaaaa acaaagaaat atagggtttc 2865001 gccacatctc caggtaattg gctgaggaat gccgcgccta aaaaagcgcc tatagagccg 2865061 ggaatgacaa gctgataaac ggtttgtttg tcaacattgc caaatttaat atgcgacact 2865121 cccgatgcgg cagtcgttac gacttccgct aaatggacag aagccgaagc cacagcaggt 2865181 gtgatgccaa acgccaataa caaagaagtt gaggtaaccc cataagccat acctaacgaa 2865241 ccgtctatta actgcgacaa taaaccaata aatgcaaaaa cgattaattt cttcatcaga 2865301 acaccccatc tatatcaatc agatattttt gactcttcat tcgaatctaa caatctcttg 2865361 gcgctttcat ataaaaaata agaggctttg ataattgcag tttcatctat tgtaaatgca 2865421 gggtggtgcc aatcatgatc accgtctgtt ccaaaaaacg caaaggatcc cggaatatgc 2865481 tcaagataat aagcaaaatc ttcccccgcg gttgatgggg cgggatcaat gacttgaagt 2865541 ttcgctttat gtgcagcgtc tcgcaccagc cccgtaattg cctcatcatt acaaagcggc 2865601 ggcggtccgg aatgccactt cacatttgcc tttaacgaga aagcggcaga aatctgctct 2865661 gtgactgcaa aaaaacgctg tttcacttga ttacgaacct ctgaatcaaa tgtacgaaca 2865721 gtgccctcaa tgaccactgt atccggaatg acattccaag tgctgccgcc gttgattttc 2865781 cctacggtta aaatcgcgct ttgcagcggg tttacatttc tgcttacaat cgtttgcagg 2865841 gcgacaataa gctgagaggc gccgataatt ggatcaaaac cattatgcgg caatgctgca 2865901 tgagcacctt tcccttctat ctctacttta aatcggtcaa cagcagccat aagcgggcct 2865961 gtttttaacc ctacagtccc aaccgcgata tccggtttat tgtgaaggcc aataaccgca 2866021 tcaatgccat ccagttggcc gtcctctatc acttttgtag cgcctgcacc cgcttcctct 2866081 gctggctgaa ataataaacg aatctttcct ttcagactgt cttgattttc cttcaataaa 2866141 aaggccgcac caagaagcgc tgccgtatga aaatcatgac cgcacgcatg catgatccct 2866201 ttatgtttag acgcataagg caatcctgtt ttttcttcaa ttggcaaggc gtcaatatca 2866261 gccctcaaag caatcgccgg accttctgac tcccctgcta tgtctgcgaa cacacccgtt 2866321 tttagagcag tagggcgaat ctgtatcccc ttttctttaa ggcatttttt tataaaagca 2866381 gttgtttcaa attcttcttt tgacagttca ggatattggt gcaggtgccg gcgaatgccg 2866441 atgagctgct tttctagcgt tgagagattt acgggattag actcctcttt caacgtcagg 2866501 atgtcatttc ctgtagtctg atatggatag gagccttcta tatttctcca ataatccaaa 2866561 gacatatgtt ccgctccttt ccctatccca atatattttc ttcagactct tcaacataag 2866621 atgaaataaa tcggttcaat ttatcagcaa gaccgcccgc cccaaatctt atatacttgc 2866681 tggaaacttt cggattatct tctttcaaaa agcttaaaaa agataaaata taaatgcgcc 2866741 tgtaagctac ttgtgtaatt ccgtactcaa aaaaccagtt atcaatgaca ttgtatacgc 2866801 ctcggttgac gccatatagg ttattacatt tcttgtaaaa gcagagatcc ggaagattta 2866861 actcctgatg ggaaagaagg ctttcttttt tgtttggtgc cataatccca atcagctcaa 2866921 agcgttttgc aacgcacgaa atatcctttt taatttgctt tgttaaagac tccaaagaat 2866981 caaaccttct ttcttctcta attttaaaga gaatgctgca ttcgattttt tctccataaa 2867041 tgtctctatg aaagtcaaac aaaaaaatct ccaatgtctt ttcaaggtta gagcccaccg 2867101 tcggtttcac accgatattc ataaccccta aatgaaattg atgattgact gtcgccagaa 2867161 ccccataaac tccattacgc agcccatgta tttttgcatc tacatttgcc gtggggaatc 2867221 caagctttct gcctaattgt tttcctttca caaccgtacc ggcaatgatc gtcaaaaaag 2867281 tcagcctcct ctctcagctt ccgcattcga tcagacgaaa cctaatgatg tgatgaatgt 2867341 aaaacggatt gatgctgcgg aatgccaaga ccgagatttt cccgcaatgt cccgccgcga 2867401 taatcttgac gataaagccc tctttcttga agaatcggaa tcaccttttc tacaaaagca 2867461 tcaagtgttc ccggtatatc cgacccaacg ataaacccat ccgccgcctc agcgttgaac 2867521 caagtttcaa ttaaggatgc gacacgctct ggtgttccga tgaatagagt ccgtggaaaa 2867581 gccatttcct gtgctacctc ccgcaatgtc agatttctgg cttttgcttc tctcttaatc 2867641 cggtctgttg tgctttgaaa cgcattcttt cccacatcgc caatatcggg aaatggctca 2867701 tccaacgggt aaacactcag atcataatca tcaaaaaaac gggccaaata agtaacagca 2867761 ttttcaatcg gtatcaattc tgcaaattca cgatacttct tttccgcctc ttcttccgta 2867821 tctgccacaa tcgggctgat ccctggaaaa atccgcacac ttgaaggatc acgcccttca 2867881 tcagcagctc ggcttttcac atccgcataa aacgcttttg tctcttctaa tgaattggaa 2867941 tgggtaaaaa tcgcatccgc atttttagca gcaaactgcc ggcctgtttc tgatgaaccc 2868001 gcttgaaaca ctacaggctc tccctgctta gagcgcccga tattcaaggg cccctctact 2868061 tgaaaatact ttcctttatg attcaggcga tgaagcttcg cctgatcgaa aaactgccct 2868121 gttttcttat tgtgtataaa tgcgtcatgc tcccaggaat tccacagccc gcgcacaaca 2868181 tccaaatgct cttgtgcgat ctcgtaacgt tcagtgtgtt ctggcaaatt agacttacta 2868241 tggttgcgcg ccgctccttc ctgcggcgaa gtaaccagat tccagccggc cctgcccccg 2868301 ctgatatggt ccagcgacat caattgtctg gagatagtga atggctcagt aaaagatgta 2868361 gagaacgtcc ctactaaacc aatatttttg gtaaccgatg ccagcgcaga taaaatggtg 2868421 atcggttcaa aacggtttaa aaaatgagga atcgattttt cagaaataaa taagccgtct 2868481 gcaatgaaaa taaaactaaa caaacctttt tcagctgttt gcgccttttt catgtaaaat 2868541 tcaatattcg tgctggccga gggatcaaca tcgggatgac gccagccgtc agttgttccc 2868601 ccgacaccgt gaatcatggc tccaaactga ataaaatctg cacgtgtcat ctttttgcct 2868661 cctttatctg tgcatgatta gcaagtgcaa gatcaaggtg ttcaatgccg atttcagtta 2868721 tcccttgata ctgattgccg cgcccgattt cgaccacagg cacatggcgc accccatatt 2868781 tcacctgtaa aatatcccga agcttttctt tctctgaaac atcgatattt tggaacggga 2868841 accctttttc attcaaataa ttcttgactt cctcacaata cgaacagcct tttttactcc 2868901 aaaccacaat gttcacaaca tcactcattc ttctgtccct ccttaacgtt ttgcagctaa 2868961 aactgcatcg ctcagcagct gataagacag ctgtttttct acagcatttt tgatcggtgt 2869021 aaaaataaca aaatcattga ttttgtatgt gcctgataaa cgtgttaatt cttctgccac 2869081 ttcttccttt gttccggcaa taatcccggt tttttgcacg atgatgtcat agggctctgt 2869141 gacgttttcc agataggcct cagcctgttc gcgggaaccg acgttgacct tacgcccgtc 2869201 tttcaaaacc acttttatcg attcacgcga cacaatatgt ttttccgctt cttcttttgt 2869261 atgtgccgca aaaacagcgg gggcaagatg aaattcagcc tcagatcctg gcgggagatg 2869321 cgcgtcaaat gctcggcggg cttccttcag cacttcctct tcaccgttaa taaagtaagc 2869381 aaagacaaaa gagattccca gttttgcagc agaaatggca ctctctgtgc ttcctcccaa 2869441 tagaaaaata cccggcttcc gatcaacctg cggcctagga cgcaatgcgg catagcggtg 2869501 ggtatcagga aaatcatccc gaacgaaatg agtaagctcc tccagttttt catcaaactg 2869561 acgcaccggt tttttatatt cggcctgcag cgcgtctgtg gacagctgaa acccgccggg 2869621 cgctttgccc actccaagat ctatacggcc gggagctaac gctgatagaa gatggaattg 2869681 ctccgctact ttataagagc tgtaatgctg cagcatcact ccgcctgatg ctaaacgaat 2869741 ttttcttgtg cttgcagcaa gatagcctaa aagaacctcg ggtgcagacc ctgcaatctc 2869801 atcattgttg tgatgttcgg ccacccaaaa tcggtgatat ccacattctt cagccatttg 2869861 tgccaatttc actgtatgct gtaatgtatc agctgctgtc tccccttcac caatcaagct 2869921 ttggtctaaa atacttaagc ggatcatatc accggctcct ttatgtgttc ttttggttca 2869981 aataaatatt ccggcgaaac acggcggaga aactgcctcg ttctgtcttt tttggtatgg 2870041 cggaagactt cctccggggt tccttgttca acaatgactc cttcatccat aaaaacaact 2870101 tgatcagaga cccttcttgc aaactccatt tcatgtgtaa caacaatcat ggtggctccg 2870161 gttttcacga tttccagcat tacctcaagc acttcaccga ccagctccgg gtcaagcgct 2870221 gccgtcggct catcgaacag cagcacatca ggatgaatgg caagcgccct tgctatccct 2870281 accctctgct tttgtcctcc cgataactga ctcggataag cgttcaattt atcttgaagc 2870341 ccgacctttc tcagttcatt ttccgctacg gcatacgcgt cttgttttct cattttccgg 2870401 gcaatcgtca agccctccat gacattttca atcaccgttt tgtgagcaaa caggtggtat 2870461 tgctgaaata ccattgccgt ctgttttctg agccagtgaa cctctttttt ggacggaaag 2870521 cggcaattaa tcactttgtc atgtatagaa atgatccctt cgtctggacg ttctaataaa 2870581 ttcaggcacc gtaaaaaggt ggttttccct gatccgctcg gcccgataat cgtcacaact 2870641 tctcccttgc gtaccgtgag atttatccct tttaatacat ggtggatgcc aaactgttta 2870701 tggatatttt taatctcaat cataaagtgc ctccttgaaa tctggctgcc tttctctcta 2870761 atactccatt tgcggattct aggattagag tcagcaccca atagataatc gctgctccga 2870821 taaacgcttc taaaaatgca taattatcag aagcaacgat agtcgccgtc cctgtaatct 2870881 ctgggacagc cactatagcc gcgatagagg tggtatgcaa aaagccgata cccaaatttg 2870941 tgaagtttgg gatggaaacc ttcagcgcct gcggcaatat tacacgccga aaggtttggc 2871001 tgtatgtcaa gccgattgaa taagccgctt cgacctgtcc ggtatccatc gccagaatgc 2871061 ccgaccggat gatttctgtg agataagctc cggcagttaa agacaaggcc atgatgacaa 2871121 acatggagac cggtatctca ttagcggacc agccgagatg aaaaaaactg ctgacttgat 2871181 ctgcaacagg cggtatccct aaataaatca acataatgtg aagaattgca ggtgtacttc 2871241 gaaagaaaga cacataaaac cttgagcaag ccaccaagcc cttaattcta aaaattctaa 2871301 caattatatt tccaagagcc acgagaaatc caaacacaat cggcaaaaca gccatcatca 2871361 atgtcagagg aatggtcttt accatttctt tcatggcgga aacgataaat ggaaagtcaa 2871421 attgcaatct tctcccccct catccgaaga aatatatcaa tgtatgttca tgtcaaaaac 2871481 agtaacaatc cttgtttgat tcttcttgat tcgtttttct gccactcgaa agaaccattc 2871541 gaataaaacc gctacagcat aataaacaat cgatagcgca atgtaaactt caagagaatg 2871601 gttgcttgag gtaatcagtg tttggcccct tccggacata tccataacac ctattgaaaa 2871661 ggctagagac gtatctttta aagaactgat caccatgttt cccatattcg gaaacgcctg 2871721 gacaagtgcc tggggcagaa cgattcgcct gaaggcctga ctaccgctta agccaatact 2871781 gtacgccgct tccgtttggc ctttatctac actgcccacc cccgctcgaa tgatttctgc 2871841 ggctgccgct gcattgctta acgcgtaggt tgcgacagca gcataaaacg ggtccatttt 2871901 tgatgtatca atcccgataa gccccgtaag cgccgggatc ccgtaaaaca cgatgaaaag 2871961 ctgcaccatg ataggcgttc ccctgaaaaa cgagatatac acttttgcca attgatttac 2872021 aattggaata ttatagatgc ggggcagtgc cagaaagagt cctaatacaa aaccgaaaag 2872081 caaggacagt gttaaaatgt ataatgtaac cggtaaataa gcggttaacg tcggcacaaa 2872141 atctccaatc atgttcatat caaacgcttt ttccatcact gctccctctc tttttaccta 2872201 atactgctct ttggaatagt cgtcaccaag ccatttcaaa ctgagccttt tcaacgttcc 2872261 gtcatcaatg atttcctgta aggctttatc aatatcgtca cttaacgttt gttcattttt 2872321 gttaaacata aaatacactt tggcatttga aagcacatta ccgacggttt tttctttaat 2872381 agtgctcgtc ttgttttgaa agtctactgc aaaaggcgtt gagatcgttg cgtccgcacg 2872441 ccccgatttc agctgattcg cagtctcatt tgcgccttgg ccctcatagg caatctcaaa 2872501 cggccgtcca ttatcctcat tccatttttt cagtacaagc gctccgttgg aggttgcact 2872561 cgtaatcacc cgttttcctt ttaagtcttc aattccacgg atcgtatcgt tattttgaag 2872621 cacagtaatt tttaaaggaa aatggttgta agcaaccttg ttaaacagaa attttttctc 2872681 acgctctttg cttttctcca tttgatgtgc cacgatatcg actttatgct gtccgaggct 2872741 gacaagcagg ttggaaaatt ccatcgtttt aaatgtgaat ttataatgtg gcaggcgctt 2872801 atcaagctct ttgatcagtt cgacatcata accggttaaa tcgccttttt catcgataaa 2872861 gcaaatattc ggaaattggg ttccagttcc gaccgtgatc gtctgtacct tcttttgccc 2872921 ggctcccgtc gtttgactgc ctgcaccgca agctgacaga actgttataa gcgaaaataa 2872981 tattgccatg aatgctgttt tcgttttcat ctcatcgccc catttatttt tcaaaacttg 2873041 attttgaata atctgccccg agccattttc ggcttagttt ttttagcgtt ccgtttttct 2873101 ccagcttttt aatcgcttga tccgtgtcat ccgccaaggt ttggctgcct ttattaaaca 2873161 taaagtacac ctcggtatct aataacacgt caccgactgt cttttggcgg aaggcgtgcg 2873221 ttttattctg aaaatcgacg gcaaacggtg tagctatcgt tgcatctgcg cgcccggttt 2873281 caatttgatt ggcggtatca ttgcttccct gtcccgcata tttcaaatga attgggctgc 2873341 cgtgcgtttt gttgtacttt gtaatataat ctgccgcatt tgacgtggcg ccaactatga 2873401 ctgtttttcc gtgtaagtct tttaatgtat gaatcttgtg attatcctct ttcaccgtga 2873461 tgtacatcgg cgagtagtta tatgggactt tatgatacaa aaaacgcttt tctcgttctt 2873521 tatttttggc catattgtgc gcaatcacat caattttttt atttccgaga ctcgtcagca 2873581 aatttgagaa atccatcgtt ttaaattcaa atgtatattg aggcaactcc ttatcgatgg 2873641 ctttcatcac ttcaatgtca tacccggtca attcaccttt ttcatttaaa aacgcaatat 2873701 tcggaaaatc tgttccagtg ccgactatga ccgtttgagc ctgacgatct gttttgttat 2873761 ttgtttgcga acatcccccg ccaagtaatg caaacactga cagcagcaaa accaatcctt 2873821 tacgcttatt cataggctgc ctcacatcat gcccagctgg gcgcacctaa aagcgttggg 2873881 ttaaatcgtt ccggaatcag aaccttgtgc atcatcacac ctatgtcccc gtctttttcc 2873941 tgctcaaaat acacttcata ccctctcctt ctgtacatgt cagcaagcca aggatgcttg 2874001 cgcgccgatg tgccgagtgt cagcgcagga gccttcagca tatctcgaag cactttttct 2874061 tcaacatacg taagcagctt acttccggcg ccttgccctt tatattccgg cagtgtcgca 2874121 aaccaccaca caaatggata ttttgaagga ggcgtctcac tctcccacgg gaacctgatt 2874181 gtaatcgttg aaatcagctt cccatcccgc tccagcacaa tcgctgaatg atgttcaata 2874241 ttttctgata ccatttggat atcagctctc gtggatggcc aatcaatatc cagctgccga 2874301 atgggctgaa atgcgctgtt aaccagtttc aacagctccg atgcatcttc aacagttgcc 2874361 agtcgaaaaa tatcatcact catttttgtc actcctcttc acaaaatata taattcctat 2874421 ttgtttacta agcttttatt gtttatacta taaagcatac tctgatcttt gactaatcaa 2874481 aaaaagtaaa ccttcacttc agtaatttta atgatgaaaa acaggaggga gcacattgga 2874541 gttacgctca atcaaaacgt ttcatacgat tgtaaaattt ggaagcttct ataaagctgc 2874601 agaaatactc aactactcgc agccgacgat atcgatgcgt atgaagcaat tggagcagga 2874661 tttaggcgta ctgctgtttg aaagaggaaa aagcctgcag ttgacaaaag cagggaagct 2874721 tttttatgaa cgaacaggag atcttttgat gcaatacgag gcgcttaaac acaacctctc 2874781 cgacttaaag gaagaagagg caggcattat caacataggg gtttcagagc caaccgccag 2874841 tctgatattc cccgagattt taaaggattt cttaatggat tacccaaaga taacggttaa 2874901 tatcaaggtt gatgacgcca atacctgcag tcaaaagctc ttagacggga cgattgattt 2874961 tgcagtctgc ggcgagccgg agctgattct tgaaaattac taccatccat ttttttatga 2875021 cacattaaat gtgattgtat ctgatcaaca tccgctcgct gagaagaagg ctgtccattt 2875081 gtctgattta gcagaagagc gcttcatatt tacgcccgcc aattgcccca ttcgcttaca 2875141 aattgaacag catttacata gagaactcgg gaatcgctac aaaaaaatgg agctcacaag 2875201 cagcatgtca catgaatatt acgtacgtga aaacatcgga atttcaatct ttaccagcac 2875261 cgcacattct aaaccgttca acggcactaa agtcattcca attctgaacc tggatatcac 2875321 cccgcccata gggctgttga caaatcaaaa agaagttcat tttgaccgcg ccacgaagga 2875381 cttgatcgcc cggataacca aacgttttca gcagcgcagc aaagaattgg aaggaacctc 2875441 tgataagacc attacaggat aactgaaaaa ataaaaacca cctcctgatt catcaggaga 2875501 tggtttcacg gtttaaagct cgatcgtctc accgaccgac atgactttgc cgactccgcc 2875561 cggcaggctg tcagcgaatg cttctgggtc ttgttcgatg accgggaatg tattgtaatg 2875621 caccggcacg acctgttttg cgcgcagcca ttcagcagca agcttggcgt cttcaggccc 2875681 cattgtaaag ttatcgccaa tcggaaggaa agcaaggtcg atatgattca attcgccaat 2875741 gagtttcata tcagagaaaa gtgccgtatc gcccgcgtgg aaaatcgttt tatcttctac 2875801 agtcagcaaa ataccggcag gcatgcctgt gtaagtgatc gttttgtttt cttcatctgt 2875861 gatggctgat ccatgaaagg cctgtgtgag cttcactttt ccaaaatcga actggcggga 2875921 gccgccaata tgcattggat gaacattcaa gcctttccag cctaagtaca cagcgagctc 2875981 gttcggggct ataaccagcg cgttattttg cttggcgatt tgttcagtat caccgacatg 2876041 gtcattgtgg ccgtgcgtta gtaagatgac atccgctttt acatcctccg gctttatatc 2876101 cgttaatgaa ttccctgtta aaaacggatc aaaaataata tgatggtcct tcgtttccac 2876161 tgtgattaca gaatgtccgt gatatgtcac tttcatttct ttcacctcgt cacatgattt 2876221 tgtttttttt attttccctt tttaaaaagc tgaaaaactt atgttgtttg attcttgtta 2876281 atgacattga ggcctccggt ggcttcaatg acagtccctg tcacaaggtc tgagttctcc 2876341 tcacacaaga aagcgataat cctggcaata tcctcgcctg taccggatct tcctatcggc 2876401 gttttttctt tgccgattcg cattctggct tcctctatcg atgcttcttt catgtcgccg 2876461 acaatgtctc ctgggcaaac catgttggcg gttatgccga attcggcttc ttcaatggca 2876521 attgtcttcg tcaaagaagc caagcccact ttcgcagcgc caaatgccga tcggtgaagc 2876581 cagccgggcg cgtgagccgc accttggaat ccgtacgtaa taatgcgtcc aaattgctgt 2876641 tttctcataa taggaataac cgctttgaat aaatgaaaga cggcgcttaa atttccttcc 2876701 agcatgccat accattcatc atcagtataa tcggctaact ttttacgttc aaatatgtat 2876761 ggtccagcgt tgttaatcaa aaagtcgatc cttccgaagc ggtttaaggc agcctctgca 2876821 atacgcagca gatcttcttt tttggtgaca tcacctttta caaattgcag ccggtcaaga 2876881 caatcgggac aggcttcctt caggcggctg actgcctcct catcctgtct gtaattgact 2876941 gttactgaat acccctttgc aagcaacgtt tcagtcactt tgcggcctaa acccttcgaa 2877001 ccggcagtaa ttaaagcatg tcgcacatga atacctccca aagcaacgtc gccgctttca 2877061 ataaagtgtt tcttcttcta ctttactata aaaggcttgc aatatcactt tttacacttt 2877121 ggcatacaaa aaaagctgcc tgtacagaca gcttattctg caggagatga agactcctga 2877181 tcaggcatat cgacataacc gctttgatat gcttctgaaa tgagccttgt tgtctcctgg 2877241 ctttcttgtt catcataaat atagcgttcc ggttcttttt tcatcattct gcctcccatc 2877301 attatagagg taggttggct ataatgacgg gattttatga aggaaatttt aacaaactcc 2877361 tgctgccacg caagctttcg ctttttcaag cgcctgttcc acctgtttga atccggtgcc 2877421 cccggcgctc attctttttt caactgcgta gtaagggtct aacacagtgt aaatatcttc 2877481 ttcaaatagt gtgctcgcct gctgaaactc gccaaacggc atatcgctta aatagatccc 2877541 tctttcgatg catgtgtaca caagtttccc gaccacttca tgcgcttctc tgaacggcat 2877601 tcctttttta gctaaataat cggccagttc cgtcgcgttt gaaaagtctt gttttgttgc 2877661 ttgcttcatg acgtctttgt ttacagtcat tgtttggatc atgcctgtga agatttgcag 2877721 gctgccctcc accgttttca ccgtgtcaaa catgccctct ttgtcttcct gcagatcttt 2877781 gttgtaagcg agcggaagtc ctttcatgat cgtaaacagc cccatcatat cgccgtatac 2877841 gcgtcctgtt ttgccgcgga tcagctccgc catatcaggg tttttctttt gcggcatcat 2877901 gctgcttcct gttgcgtacg tatcgtcaag ctcgatgaat ttaaactcct gcgagcacca 2877961 taaaatgatt tcttcagaga aacgggatag gtgcatcatc agcatactgc tgttgcttaa 2878021 aaactccaaa atgaagtctc tgtcgctgac gccgtccaag ctgttttcat aaatggcatc 2878081 aaagccgagc agttccgctg aataatcacg gtcaattggg aaggttgttc ccgcgagcgc 2878141 cccgcagccg agcggagatt tgttaatccg cttcattgaa tcctgaaaac gctccttgtc 2878201 gcgctcaagc atccagaaat acgcaagcag atggtgagcg aatgaaatcg gctgggcgcg 2878261 ctgcaaatgt gtgtagcccg gcagaatcgt ttcaacgttc gcttccgcct tttcaatcag 2878321 cgcactttgg aatgcctcaa tcagctcgat gatgtggccg acatgattct tcaagtataa 2878381 atgcatgtca gtcgccacct ggtcattccg gcttctgccg gtatgcagct tgccgccaag 2878441 aggaccgatt tcgtcaatga gcattttctc aatgttcaaa tgaatatcct cataatcgac 2878501 tgagaattcc aatgctccct cctctgcttt ttgcaaaagg gtattcaggc cctctcggat 2878561 tttcaactct tcttctgctg tcagaatacc gcattttttc agcatggcag catgtgcgag 2878621 agaccctgta atgtcttcag caactaaatt ttggtcaaat gatatggacg cgccgaactc 2878681 gtcgacccat ttttccggtg ttttttgaaa tcggcctccc caaagcttct tcatgcttta 2878741 atctgctcct tctttttcac gatgctgttc acttttgtcg gaagtcccca aagctcgata 2878801 aatccgattg ctgcatggtg atcaaatgca tcgtcttttg tatatgttgc aagtttttca 2878861 tcatatagag agtattccga tttacgtcct tctacaattg catggccttt aaacagcttc 2878921 acgcggacaa tgcctgtgac atgcttttgc gtttctttta agaaagcgtg cagcgcgtct 2878981 tttaacggtg agaaccataa gccgttgtaa atgatttctg acattttttg ctcgatgatc 2879041 ggtttaaagt gggctacctc tttcaccagt gtcaaatctt ctaattcttt atgcgctttg 2879101 atcagtgtca tcgcaccagg gcattcgtat acttcccggg atttaatgcc gacgaggcgg 2879161 ttttccacgt ggtcgatacg tccgacaccg tgcgcgcccg ccatttcatt cagcttcaag 2879221 atcagctcag aaagcgagta ggaaacaccg tcaatggaga caggcacgcc ctgttcaaat 2879281 gcaatttcaa tcacttccgg cgtgtccggc gttttttcca gcggagctgt taaatcgtat 2879341 gcaccttctg gcggcgccgc ccatggatct tctaaaatgc cgcactcatt ggcgcgtccc 2879401 cagaggtttt ggtcgataga atacgggctg tcaagattga tcggaatcgg aatgccgcgg 2879461 ctagccgcat attcaatttc ttcttcacgt gaccactgcc attcgcgaac cggcgcgatg 2879521 acttctaggt cagggtttaa tgatttaatg gagacttcga aacgaacctg gtcatttcct 2879581 ttccctgtgc atccgtgggc aatcgcctgt gcatcttctt tttccgcaat ttcaaccagt 2879641 tttttcgcga tcagcggtcg agataatgcc gaaacaagcg ggtattttcc ttcatacatt 2879701 gtgtgggcct gcaaagagat aagcgcgtaa tcctgtgcaa attcttcttt tgcatcgatc 2879761 acgtaggagt ttgtcgcgcc gacttcaagc gctttctgct gaacaaatgc caaatctttg 2879821 ccctcaccga catccaggca gcaggcgatt acattatatc cttgctcctg aagccatttt 2879881 attgcgacgg aagtatcaag acctcctgag tatgctaata cgactttttt ctgttctgac 2879941 atgataaaaa tcccctctca accgtgtttc tattttgtat aaaaataaat tatatttaat 2880001 aaaaatacat tttgtatgta tacactttaa caagtacgtt tcgttttttc aagcctttta 2880061 taaaaaaaac ttcacctaaa tttcaggtga agtttcatag tatttattca tttacttgtc 2880121 ttttctgatt tctctgacca catgcgcaag ttcgggaata atcagcttat tcattgccag 2880181 ctttactgcg ccgcttgagc ctggcgttga gaaaacagcg gtatgctgaa tgacgccggc 2880241 agttgctctc gacatgattg cggcagagcc gatatcctct gtataactca gcatcctgaa 2880301 tatttctcca aagccgggca gttctttcga aaacagcggc gttatggctt caattgtgac 2880361 atcccgatct gctatgcctg tccctccgtt taagagtacc gcgtctgtct gttcatccat 2880421 gcagcccgca agcactgacc gttgcaaagc atccttttcg tcttttacaa tttcatatgc 2880481 ggcaatatga tgaccggctt cttctaaaaa tgagatcatc agcttgccgc ttttatcggt 2880541 ttcatctgtc ctcgtgtcac tgacagtaat cactttgcac cgaacgatat cgggagcttc 2880601 ttgtttatgc tcttgaacgc tcattggccc acctctttta tgttttctgt ctgtcactat 2880661 catgcatcaa caaaaaagca cattcaagag aatgtgcttt catgcgattt attttgctaa 2880721 acgaacaacg tcgcgcgcaa tcatgacttc ttcatcagtc gggatgatca tgacttttac 2880781 tggagaatgc ggatagctga tgaaagcttc ctcgccgcgc acgttattaa gcgcagggtc 2880841 ccagtatacg cccatgaatt ctaaaccgcg aagaacgcgt tctctgactt ccacactgtt 2880901 ttcaccgata ccggcagtaa agatgatcgc atctacaccg ctcattcttg cagcgtaaga 2880961 accgatgtat ttgtggattc tgcttgcgaa tacttcaaga gccgtttccg cgcgctcatt 2881021 tccttctttc gtagcttcaa cgatgtcacg aagatcgctt gagaaaccgg aaatgccgag 2881081 cagtccgctt tttttgttta atgtattcag tacttcgtca gccgtttggc ctgttttctc 2881141 catgatgtat gggatcaggg cagggtcgat gtttccagag cgtgtgccca ttgctacacc 2881201 ggcaagcggc gtaaagccca tggatgtgtc aatagatttt ccgccttcaa cagcggcaat 2881261 acttgctccg tttccaaggt ggcaggaaat caggcgcaag tcttttaacg gacggccgag 2881321 aagctctgcc gcacgctcag ttacatattt atgtgaagtg ccgtggaagc cgtatttacg 2881381 gatgccgaat ttttcatagt attcatacgg caagctgtaa aggtaagact gctcaggcat 2881441 tgtttggtgg aatgctgtat caaatacagc taccgcagga acatttggaa gcacttcttt 2881501 gaacgcttta attccaacga tatttgccgg attgtgaagc ggtgccaatt cagaaatatc 2881561 ttcgatttcc ttaatggttt catccgttaa taaaacagaa tcgctgaatt tttctccgcc 2881621 gtgaacgaca cgatggccaa ttccgtcaat ttcattcaag tctttaataa tgccgaattc 2881681 cgttaactta ttcagcagca ttttaacagc taccgcatga tctggaatat cagttacttc 2881741 tgtatttttt tcgccgttca cagaaattgt gaatacgctg tcggcgatac cgattcgttc 2881801 aactaaaccc ttcgttaaaa cggtttctga aggcatttcg aaaagctgaa atttcaaaga 2881861 cgagcttcct gcgttaattg caataatttt ggacatgatt gacgctcctt tatactctgt 2881921 atcaacaact tcgtttttcg tacttttttc ccggtgaata tcaacatctt ctccgaaaaa 2881981 tatctgactt ttccatttaa acattgtcat gtcggctttt caagtcaact tgcgtattga 2882041 taacgcttac aataagaagt cgttattttc agacacattc actataggtt ttgtattgat 2882101 gaacgcttac aatttgcggt ttttccctct gtattttgtg tttcaaagct ggattcaatt 2882161 cgtcaagtcc ggtcttcaaa agcataaata aaagcagctt aggcatcgac ctcatacggc 2882221 tgtctaagct gcttttaaaa cacttacttt tcttttttaa accattcatc aaattgagcc 2882281 atcatatcaa gcatcgcctt ttgattggag aaagacggaa gattcgcaag cagaatttgc 2882341 cccggcgctt tcgtattctc tccttgtttc tgaagcacaa ggatgctttt ggcatgagct 2882401 tcgtctttaa aaatagattt tggcagctgc aacagtgcgt tgatatgaac cttatctttg 2882461 aaaaactgtt tcagcttgcc gctttgggag ctctcaaaca aatgattcgg aatcataaaa 2882521 aataagtagc cgcccggttt ggtatgcttg acgctctgtt caataaacag atgatgagcg 2882581 aaggaatggc cttcgtcagc tttgagctca aacgcttctg ctccttcgtc attcggataa 2882641 tagccgactg gcagatcaca aatgaccgtg tcaactggat cgataaacaa cggctcaagg 2882701 ctgtcctggt ggaaaagctc aagctctttt ttcagaaggt tcgcttgggc ataggcgatc 2882761 ttcaagagca catcatcaat ttcaatgcca aagctgtttg ccgttttttc agacagctgg 2882821 ttcagcacgg taaacagaag gttcccagtt cccagggctg gatcaagaat ggtcagttcc 2882881 tttttgtccg ccataaattt attcaccaaa tagctgatga aaagcccgat cgtatccggc 2882941 gtcatttgtc tgtttggatg cgagatatct ttcattcctt taaggacggc aagctgaaaa 2883001 gccttgcgta cccactcatg ctcatacgtg ccgaattccg ctttttcaag cagagcctga 2883061 agttgtttgg ttttctgatc agcaggcagt ttcagctgat ccgttttttc aagaaaatac 2883121 atttctcctg cttcggccag cgcctctata tatgaaatct gcaattcatt ctttatcata 2883181 atcgcggctt cgtttaacag ctcatacacc gcacctacat ggtctttttg catattgtgt 2883241 tcctccttgc catgaaaaaa gctccggcgg cagcctggag cttttttccc tgcttacttt 2883301 actaatgcct tagcagcctc aattggcttt tcatagttcg ggtggtttgt tgcttcgctt 2883361 acatattcag cgtaaacgac ttttccgttc tcatcaagga caaatacgga acgcgcaagc 2883421 agacgaagtt ctttaatata cacaccgaac gcttcgccaa atgacatatc tctgtggtca 2883481 gacagtgttt ccactttgtc aattccgtta gcgccgcacc agcgcgcttg cgcgaatgga 2883541 aggtctgcac tgattgtgta gacgttgaca tctccaagct ttgcagcttc ttcgttaaaa 2883601 cggcgtgttt gtgcatcaca aacacctgta tcaattgaag ggataacaga aataatcgtt 2883661 acctttcctt tcatgtcagc taacgatttt tcttcaaggc tgttagtcag cactgtgaaa 2883721 tcaggagctt gatctcctac cttcacttct tgtccgacaa gtgtaaccgg accgcctttg 2883781 aatgtaattt cagccattat aattcctccc ttttgtatgt atgtctctat catagtaaag 2883841 tttcctgcaa actgcaaagt ttatgccaaa aaaaagttaa ctgcggccag cgcagttaac 2883901 ctttttttaa taattcatat tgttcatttg gttttgattt tggccttggc tttggttttt 2883961 gttatttttc ttgaacattt gctggatgcg ctcgagtgtt tgaggggctg cgtctaaaat 2884021 tttctctatt aaatgggtat tttcatctaa atgaagcatt ctgatgcctg tcgatccgac 2884081 aattaaaaac gcgatcggcg taatggacac accgcccccg cttccgcctc cgaaaggaag 2884141 tttctgttct cttgtctcat cgtcttccga tttcttttcg gccggctttc cgccaaactc 2884201 gcttccgcct gcggcgaatc cgaatccaac tttagaaaca gttaaaatca cacttccatc 2884261 aggcgtttcc actggatctc cgatgatggt gttaacatca atcatttcct tcaagttttc 2884321 cattgcggtt ttcattaaac cttggatggg atggtctgcc atatacgctt cctccttaaa 2884381 ctgatgaatc attctttgaa gtcattctag ccgacggatt cttctttaat acggatagct 2884441 cccgtccgta tttgacgaat ttgaaagctg caagcatagc atgtccaaag cgaaaaaaga 2884501 atatacactg aaaatgggtc ttggaaacag ggacttgaaa cgacgggatc acctcataga 2884561 caggtttatt cacaaagtcc aggtggtcgt agagcattgc tgcgataccg cccttcacgc 2884621 cccatacagc accggttaac acacctgtca ctgccgcgtc ctgaattccg attactgtaa 2884681 cccattctag ttttgtgata tgtaaatgcg cgagaaaaga cgcgctgatt ttccgcagtc 2884741 tggtgacctg atgcaaaagc atttcgattt tattaatgct ttgctgcaca tcgttttgtg 2884801 taattttttt ctttccgctg ctttttttca ttttggattc agttttttgt ttgatatcca 2884861 ctgttccgtc ttctttgttc accttaatcg ccgggattgt ttttttgatc cttataaggc 2884921 caaacagcgc cgtaatcttc aaggtcaatt tgtcattatc atcggcatga agatactcca 2884981 gcgcgacatg gattttcatt ctgagaagca gtacgatccc tatgagaata agaatggctg 2885041 tcagtacata caccatattc ttcacttcct ctaggagcat tatcgccaat tcctaaaaaa 2885101 ataaacccgg acggaagtcc gggttatcgg ttatttgcgg tataattttt catgcaccac 2885161 ggtggtatcc gcgatgtaat catgaatccc ttgttttgta ggtgaaaagg caacaacgat 2885221 atataaaatc caaatcttat caatataccg tccaaccact tcacgaaaaa tcactgtact 2885281 ccatgtcagc ttgctatctt gcttcacaga aaccactttg aggccgaaca ccattttacc 2885341 aagcgtctgc ctgaagtatt ttgtcatgag tgcgaaatag gcaagataca caataagcgt 2885401 tgtcacactg taggccgaga aggtaaacat gccggatgtt ttcggcagat ccaatacggt 2885461 aaagagggga gaaacgagca aatggtttaa tccccatatc acgagccaat caagcaggaa 2885521 agcccagaaa cgaacccaaa agccagcata ggcatgtgtc agcagctccg cttcttgcgg 2885581 gcctttgatg tcattgcgct ctaactcttc atatgtcgcg tccattattg ttccctccta 2885641 cttcgcatag agatacatca ttctcggcga accggattgc gatagaattt ctctcatatt 2885701 caaaaaatca atttcacttt taaacatttt gttcgcgccc atggaaaaca gtgagcctaa 2885761 tccgaagctt tcctcataag aaatgacaga ggcgtttttc aaatccttgt gatccttttt 2885821 catggccgta atggtatcgt cataaaaacc aagctcatca acgaggttca gttttttcgc 2885881 ctgccgtccg tcatacacgc ggccgtccgc aattttcttt acctctgctt tcggcatgcc 2885941 gcgccctttt gaaatgacat caacaaagcc ttcatacgaa ttatcaacca tcgattgcat 2886001 gatgtttttt tcttctttcg tcatctcacg ggaaggagac ataatgtcct tatgggcccc 2886061 gctcttaatc gtttcaaaag aaatgccaag cttgtcggca agctttgaat aattgacgct 2886121 ttccataatg acgccgagtg acccggtcag ggtttccggt gtcgcaaaaa tcttatcagc 2886181 cgctgttgag atgtaatagc ctcctgatgc tgccatcgaa cccattgaca cgtaaatcgg 2886241 ttttttcgtt tctttcttga tttcttccag tttcttatgt atttcagcac tttcatacac 2886301 tccgccaccc ggagaattca ccttcagaac gatacctttg accgtcttgt catcttttgc 2886361 gcgctcaagg ttttttaaga acgttctgtg gttatatccg tctgcaccaa gcagactgct 2886421 tgagtcccca ttatcctgaa tggtgccgct gacctctaat acggcaattt tacttgaggg 2886481 actgccgttt tccagcgtct tctcctgcga ttcatccgtc agtgatgtga gatccgtttg 2886541 agcgcctttg acgctttcaa agaaactcat agagatgctg acgataatag acacgccgaa 2886601 aatccccaga gcaatcacta atgcaatcca tctttttgca ttcatttttt ctcctccttt 2886661 ttcctaaact ctctcattat acgattcaat atgaaaaatg tttcacttca tgagaaagct 2886721 ccggcttaac gggctgccgg caaacgtggt acacttatgg ccaaaggtat tttatcacaa 2886781 atactggatg gcagaaaaac ttaaatatga cagcaaaggg gaaatgggat atgaccgatc 2886841 aacgccgtaa tgtttatttt tttcacaaac aggatcagga aacgaacgaa caagcccgct 2886901 cgttaacaca attagcggaa gagcatggat ttaccgttgt gaaccagcac tcagacgcca 2886961 atattatcgc tagcattggc ggggacggca catttttgca ggcagtcaga aagacgaatt 2887021 ttcgtgacga ctgcttgtac gtcggcatta ccaaaaaggg gaaagctcat ttatattgcg 2887081 actttcatag tgatgagcga gaaaaaatgg tcgatgcaat gacgtttgaa caaattgaag 2887141 tgagaaaata cccgctgatt gaagtgacag tggatcaagc cagtcctttt cactgcttaa 2887201 acgaggtatc catccgctca agcatcatca aaacctttgt gatggacgtg ctgattgacg 2887261 atctgcactt tgaaacgttt agaggtgacg gaatgattat ctcaacgcct acagggagca 2887321 ccgcctataa caagtctgtt gcaggagctg ttgttgatcc attgcttcca tgcatgcagg 2887381 tatcagagct tgcatccctt aacaataata cctaccggac actcggctcg ccatttgtcc 2887441 tcagctctga ccgaaagctg acccttcgtg tggtgcagga cggcaacgaa cacccaatca 2887501 tcggcttgga caatgaagca ctcagcacga gaaatgtgaa aacgatcgaa atcaaactgt 2887561 ctaataagaa aatcaaaaca gtcaaactaa aggacaattc attttgggaa aaagtgaagc 2887621 gtactttttt atagaaaata aaaggacagg ctgctgcctg tccttttatg atttctcata 2887681 tacaatctgg ccgttaatca cggttttttt aatctctaaa agatgaagct gtgcggggtc 2887741 aatggcaaac ggatcaccac tgagaactgt aaaatccgcg tcatagcctt ccgcaatttt 2887801 tccgcgtgac ttctctttat aaatgatacc ggcgctacct tctgtataaa gctttatcgc 2887861 ttcatataca ggtaaacatt cactttcatt atagcttggc ccgttttgct catgactgct 2887921 tttccggagg accgcggact ggatccctag aagcgggtca acaggctcaa tcggggcgtc 2887981 tgaaccgccc gcgcataaaa tgcctttaga tatgagggtt ttccaggcaa atgcagtctt 2888041 catccggtct tttccgagac ggtcaatgac ccacggaaag tcgcttgcaa cgaagtgcgg 2888101 ctgaaggtca agtgcgatcg gcatgcgtgc tgctctctcg attaattcgt tatcaagcac 2888161 ttgagcatga ataagccgat catgccggcc gtttttgggc ggatgctttt ctattgcgtt 2888221 cagcactttt tcaaaagcaa gatcgccgat tgcatgaaca gcaacctcca tccctttttc 2888281 tctcgctttg cgaatgagcc ggccaagggt ttcgtcatcg tgaacctgaa caccatttgt 2888341 tgatggatca tcctgatatg gttctttcaa taaagccgtt ctcccgccaa gcgccccgtc 2888401 cgcaaagatt ttcatagcac cgaactccac atacgggccg gacagcttct ccagctgctc 2888461 ccatcgatcg acagcttcat gatgaacgag caaatggcag cgaaacggat actttccgcc 2888521 agcggcagct ttctcataag ctttcatcgg caccgaaaca tcaccataat aggacaagtc 2888581 ttccgaatga ccgcccgtca ggccttttgt ccagcaatcc tttattgcag ccgttaatgc 2888641 ctcatcaaca tagtgctggg agactggcgg gacagccttc agaatcaaat cctgcgcctt 2888701 atcaaacagg agtccggtcg gctcgccatt tgcatctttt acgatgactc cgccgtcagg 2888761 atcaggagta tttcttgaaa ttcccgctgc ttgaagagcc gcagaattga cagctattgc 2888821 atgccggcat atacgcttga gcaagacggg cctgtcagga aacaggcgat caagatcatg 2888881 cttagtcaag tagtcaggtg tctcaaactg attttcattc cagccttctc caatgagcca 2888941 atcgttttta ggaagctgcc gctctctttc cttcgcagcc tgtaaaattg aatctttcga 2889001 cgtcagtgcg gacagatcga gctgaagctg tttctcaccg tggccgatca aatgtagatg 2889061 gctgtcaaca aaaccgggga acatcactgc tccgttcagg ctgatttctt ctgtttccgg 2889121 cgacccgtac ttttccttca aacgttcata gctgccggtg ccttttataa caccatcctc 2889181 aacataaact gcctcagtcc gatcgccttc ttcgagcatc gtataaatga aaccgccgtg 2889241 ccatatcgcc ttcattcacg ttcactctct ttctttacgc ctttttattg gctttgagct 2889301 gttcttcacg ttttcttaat tccactcgtc tgatttttgc agaagccgtt ttcggcaggc 2889361 tttccacaaa ttcaatttct ctaggatatt tgtatggagc ggtaatcgtc ttcacatggt 2889421 tttgcagcat tttgacaagc tcatcactgc gtttttcatg attttgcagg acaacatatg 2889481 cctttacgat ggagcctctg atttcatcag ggcttgcgac aacagcacat tcttttactt 2889541 ctgggtgctt aacaagcgcg tcttccacct cgaaaggccc gatcgtatag ccggagctga 2889601 taataatatc gtcatttcgg ctttcaaacc agaagtaacc ttcctcatct tttcttgctc 2889661 tgtctcccgt taggaaataa tcgccgcgaa tttgtgtttt cattctttcc ggatctttaa 2889721 aatactcttt aaagagcgca ggcgtactga ggtgaacagc gatatcgcca acctcaccag 2889781 gtttgcagat ttcaccgtct tcatttatga tctccacctg atttcccggt gtcggttttc 2889841 ccatgcttcc cggtttaata ggcgtatctt tcaaaacacc aaccaaaagc gtgctttctg 2889901 tttggccata tccgtcccgt accttaatgc caaagtgctt ttggaaaaca tcaatgactt 2889961 cacggttgag cggctcacct gcggaaacag cgctgtgcag ggcagaaaga tcaaagcgtt 2890021 tcaagccttc aaccttcgcc attaagcggt attctgtcgg agtgcagcag aaaacattga 2890081 ttttgtagcg atttaaaagc tctagatatt tttctgcttt gaatctgccg tggtacacaa 2890141 aaccggttgc tccgctgcca agcaccgcta aaaacggact ccatacccac ttttgccagc 2890201 caggggcagc agttgcccag acgatatcct tttcagaaat gtcaagccaa gcgccggcag 2890261 aagtttttaa atgagcaaat gcccatccat gtgtatgtac aacacctttc ggctgacctg 2890321 ttgtcccgga tgtataagat aagaaagcca tatcatctct tgttgtgtca gctgttttaa 2890381 attggcttcc gtccgcttca attgataaga ggtttttcca gccggcatca ttttcaccaa 2890441 tagacagtgt aatcagtttg tcagccgtac tgacatcccg gaaagcgcca ataaattcgg 2890501 agtagacgat agcgcctttt acctctgcat gttcaatccg gtattcaaga tctttcgcgc 2890561 gaagcatttc ggagcacgga atgacaacca ttcctgattt caggatagcc aaataaacag 2890621 cataggcttc aagcacccgc ggaaccatta caatcagctt gtctcccttt ttaaatccaa 2890681 gatcagctaa ggccgctccg attttatttg tttcttccat cagcttttca tacgaccaag 2890741 attcttgctt gcccgactcg tcctcccaaa gaagagcggt tttttgtcca gcagcactga 2890801 acttttccat ttcattcact aaattatatt gcacaggggc aattaaatct tcacgtttta 2890861 acacgaacaa ctcctcactt tctccaccca ttatacataa atacaggctc tttccgtaag 2890921 gatatgccta aaagcaacct ctgtaaacat agattttata ggccgctggt ccttttttat 2890981 atgtaaaaaa tgaaaaagag tggggatacc cccactccta agccattatg tgaaattgta 2891041 aattagaatt gtcctccgcc catgttttgt tgagcaaaag atacaagacg ttttgtgatc 2891101 tctcctccaa cagaaccgtt agcgcgagaa gttgtgtctg ctccaaggtt tacaccgaat 2891161 tcagaagcga tttctaattt catttggtcg atcgcttgag cagctcctgg tactaaaagg 2891221 ttgttgctgt tacctgagtt attgttagcc atgtgtctca cctccttgtg agtatagaat 2891281 gtgtcaaaac acatggcttc attcagaaaa actttggtaa ttgtatacag gagctgaaaa 2891341 ttgatttaaa agagttcagc gaatttatcg ttagcttctt gttcgctata aagggtcatt 2891401 gtctcaatgt tatctaccgc ttcttgaata tacggctcga aatcaacaaa gctttcaaag 2891461 tgttcaattt tctctttttt agggcgtgtt ttcgggcttg gcggtgtaaa gatcgtgcag 2891521 cagtcttcaa acggctgaat acttgtctca tatgtgccaa tttcccgtga tttttcgatg 2891581 atttctgttt tgtccatggc gattagcgga cgcaaaatcg gtgttgacgt caccgcatta 2891641 attgcataca tgctttcaag cgtttggctc gctacctgac cgaggctttc tcccgtaata 2891701 atggcaagcc cgtttctctt ttctctgatt ctgtcggcta tctgaagcat gaggcggcgg 2891761 gttgccgtca ttgtgtaatt ttcaggaatt tgtttttgga tgagctcttg cgtttttgta 2891821 aatggaacaa tatgaagtgt catgcttccc ccaaaacggg acagacattt cgccagatcc 2891881 attacctttt gctttgcgcg ctcgcttgtg tatggcgggc tgaagaaatg aacagcttct 2891941 accgacaatc cccgtttcat cgcataaaaa ccggccacag ggctgtcaaa accgccagaa 2892001 agcatcagca tcgcttttcc tgctgaacca actggcagcc cgcctgcacc tttttcatca 2892061 cgaattgtca aaaatgttgc ttcttccctg atttcgattc tgagcgggat gtctgggttg 2892121 cgaacatcga ccgtcaatcc ttctgtattt cgcaaaatat ggccgccgat ttcagcgttc 2892181 atctggtttg tatctaattc aaattgctta tacgctctct ttgtcgcgac tttaaacgta 2892241 tcacctggtt tatactgatc tttgatagcc tttagtgcgg ttgccttaat atcatcaagg 2892301 cggctgtcac acttaattgc caggctgaag ctttgaatcc caaacacttg ctttaaatga 2892361 ggaaaaagag cctcaggatc ctctccattt aatgtaatcg tcatacgatc cctgttggaa 2892421 aagtatttta aattcggata gtctttcaaa acgagtctga tgttttgttt taagcgctca 2892481 ataaagcttt ttctgttttt gcctttggtc gaaatttccc caaaacgaat taatatatga 2892541 tcgtaattca tgttctacct catcatttcc cttaattttt tgatgccagg acgaagcgcg 2892601 ttcataaacg gttctgccac atcgcttgtc tggctgtaat ttaaactgat tctgatgctg 2892661 cttccggcaa tctgctctcc tttgcccatc tctaagagaa ccttgctggg cttatgttct 2892721 tttgccgagc aagccgatgt tgtggagacg aatatatcct gttcctcaag catgtgtaaa 2892781 agcacttccg ctttaatccc cggtacagag aaattaataa tgtgcggcgc gctattcatt 2892841 tgaggcgtgt tgataacgac gccctcaatt tcactcagcc tattcataaa caattccttt 2892901 acggcagtca tcgtgtcaag ccgtgtgtca aaatcagcag aggccagatt aatggccttg 2892961 gcaagcgaaa ccgcaccagc agtatgttct gttccggccc gtatgccttt ttgctgagag 2893021 cctcccgtta tgagcggaat aaggcgtgtt ccttctttta caataagtgc gcctgtcccc 2893081 tttaggccgt gaaatttatg ccccgaaatt gaacatagat caatgccggc cttttcaatt 2893141 gccaagggca ctttatagat gccctgcaca taatcgacgt gaaacaaaat gttcgaatgc 2893201 tctttcagca cttctcctgc cgcttcaatc ggctgcacgg aaccgacttc attgttcaca 2893261 tgcatcatgc tgacaagcac ggtatcggga cggatggctg cttttagatc ttcaatagaa 2893321 acaaatccgt cttcattcac agaaagataa gtgatatcaa acccgaacaa ctctttcagc 2893381 tgttctaacg attccgtaac ggatggatgt tcaatagaag tggcaatgat atgtttgcct 2893441 gtttttatct ttgacaaagc cgctcctttt aaagccgcat tattggcttc tgtggcgcct 2893501 gacgtaaata caatatcata tttttttagg cctaaggacc ttttgatttg atttttggct 2893561 gcttgaagca gctgttccgt ttcggctcca tatcggtgca aagatgaagg attgccaaag 2893621 tatcggctgc tcgtctgttc atatacgttc aagacttcat cgtaaggctt cgtcgttgaa 2893681 ctattatcta aatatatcat cttttttact cctttatgaa agcggtacaa ggtatgatat 2893741 ttatgttacc ataacaaaat ttaatagaaa attacgaaaa actagtattg acttctaatt 2893801 tttttaccat ataataagat ttgttcgttt cgtcatatta tctgacaatt aattgacaga 2893861 atattttaac ataattatta ggaggatttt tttcatgaaa cactcactgc ctgtcaaaga 2893921 taccattatt attggtttca tgctatttgc gttattcttt ggagcaggaa atatgattta 2893981 tccgccggaa cttggacaag cagccggaca caacgtctgg aaggccatcg gcggattttt 2894041 actgacaggg gtaggcctgc cgcttctcgg cattatcgcc atcgcattaa ccggtaagga 2894101 cgctaaaggc cttgctgaca aagcgcaccc tgttttcggc acaatcttta ctgtcgtgct 2894161 ttatttatca atcggaccat tattcgccat cccgagaaca ggaactgttt catatgaaat 2894221 tggcgctgtt ccgtttttga ctggtgtacc agaaagactt tctttattaa tatttacact 2894281 tatctttttc ggcgttacgt actatttagc gttaaaccca tctaaggttg tggatcgagt 2894341 cggaaaaatt ctgactccca tcaaattcac aattatttta atcattgttc tcaaagccat 2894401 cttcacgccg atgggcggat tgggcgccgt gacagaagca tataaaggaa caccggtttt 2894461 taaaggattt ttagaaggct ataaaacaat ggacgcactt gcttcaattg tatttggcgt 2894521 tgtcgttgta aatgctgtaa aaagcaaagg cgttacacag tctaaagctc ttgctgcagc 2894581 ctgcattaaa gcaggtgtga ttgccgcttt aggcctgact ttcatttatg tatcccttgc 2894641 ttatttaggt gcaacaagca caaatgccat tggtcctgtt ggtgaaggag ctaaaatttt 2894701 atctgcgtct tcccattatt tattcggttc attgggcaac atcgtactcg gagcagcgat 2894761 tacagtcgca tgtttaacaa caagcatcgg ccttgtcaca tcttgcggcc aatatttttc 2894821 aaaacttatt ccggcattat catataaaat tgtcgttacg attgtcacgt tattcagctt 2894881 gatcattgcg aatttcggac tcgcgcaaat tatcgcgttt tctgttccta ttttatcagc 2894941 tatctatccg cttgccattg tcattatcgt tctttccttc atcgataaga tctttaaaga 2895001 aagacgcgaa gtgtacatcg catgcttgat cggtacagga cttttcagta ttttagacgg 2895061 tatcaaagca gccggttttt cacttggatc tttagatgtg tttctaaatg cgaatcttcc 2895121 tctttacagc ctcggcatcg gctgggtgct tccaggaatc gtcggagcgg ttatcggcta 2895181 tgtgctgacc ttattcatcg gaccatccaa acagcttaat gaaataagtt aatgtcacag 2895241 aacgcctgcg ttattgcgca ggcgttttgt aataaaaaaa gagcctgctc attacactgc 2895301 gggctctttt tcatggtcgt gattatctaa gcggatatgt cagctttgat tttttcaact 2895361 gcacctggcg cagccttttc tacagcggca gcggcaattt cataagagtc gtcataatca 2895421 aaagcataaa aacgtctttc cgcttctttc agctgttcag ataaaatatg attctggctt 2895481 ctgaaccggt ttccgaactg aatgattttt tcaatgagga tgacctgctc gacaagttcc 2895541 tctgattccc ggcttgccct gttgacgata tcttctgctt gtttcaaatg ggctccggct 2895601 tcttccatat ttaatggaag ttcgtttagt tgattgaccg tttcttgaat atgatgatgc 2895661 gcgttctcca gcatctcttg aatatggctc ggaatgcctg gaatgttgct agtcttcagc 2895721 agtcttgctg tctcagaaat tgtttttttc aaattgctga gcgtctccct cgcctgaagc 2895781 tcttcttttc tcagcgcttg cagattttca cgatactcgg catgctcttt tttcacttct 2895841 tcaatttgct tctctattga agcaacttct tctactaaaa gtgagtaggc gacatgctct 2895901 gcatcaagct tatctttaac ggatgatagc agctttccaa tttcatcaag gcgcttttca 2895961 aaagcctgct gtttgccgag ctcaccggct gtcagcctgt agctttcctt caccagctca 2896021 gtttccgctt tcgtatgctc tttctcttct ttaagcttgt cgtaagcaat aatcaattca 2896081 ggcattttgc ttagtacgga ttgaccggct tcaacttcgc cctccagctg ctgataaaca 2896141 gattgaatat tttcgtcaat gagctgcagg attgcggacg cttcatcaat atccagttca 2896201 gtcatcagga catgttccgc tcgtttcagc tggtttgaca gattttctaa ttccttatca 2896261 agctggatat gctcaagctt gtaccctttt tctttcattt cgccatagcc atccttgagc 2896321 tttgcaatct gtccgggcac cgtctgttta cagtcagcta acagcttcgg cacatcatct 2896381 atgtatgact gaagccgttc aagattgcgg tcctgctcaa gcagtacttt tcgtgcagta 2896441 atatagtttc cgccttctgt ttcttcttca aattgtttga tgccgctcca aatttcgtcc 2896501 agatcctttt caaggctgtc ataaagctcc ccgtaaaggt ggctgtaagc cagcaggttt 2896561 tttcgagatt tcgaatagcg ctccctcacc tgttcaatct cttcacggct cttttcctca 2896621 cttgtgacaa gatcgctgat ttcccgaaga atcttttcaa tgcttgattc agccgctgtc 2896681 agcaggtcgt cgatatgaac gagcacttga ttggcctttt taaaccggta tttgtctgca 2896741 ttttcctcgg catcataaag gagctcttca actttcggca tgtgggctgt gacaatctca 2896801 tcccattctt cacgccactt ctcaaagaac tcttctgtct gacccgtcat ttttaaatgt 2896861 tttattttag acatttcttc cacgatcgac cgattcagaa tttcaatctt ccacgattcc 2896921 agccggtcga tttcggcgta gatttttttc ctgaaaaagt agcctgccgc aaacagcgca 2896981 agcagtacaa ttaataatcc aatgacaaac tccataatga gcccccttgc tgtttacctt 2897041 aatctgtcag ggtgttttat ttattcagaa agatttcagg atatgtattg agaaaaactg 2897101 tcgttttcat tgttattatg ataccatgta acaaacattt tttgaccaga aatcaaaaac 2897161 tttttgtgca aaatcggcag gatttgacta ttttttcatg gggtgacatc aatgcaaaag 2897221 cgagacggac atattcacac accattttgc cctcacggct ccaatgacac actcagacaa 2897281 tatgcagaag aagccttaaa aaaagggttc gaatcgatta cttttaccga acacgcccca 2897341 ttgccgccat cttttaccga tcccacgccg ctgaaagaca gcgcgatggc gcaagcttct 2897401 ttggaacgct atattcatga aatttccgga ttaaaaaaag aatatcgcgg acagcttagc 2897461 atacggacag ggcttgaagt cgattatatc gctgaatttg aagacgaaat tacattattc 2897521 ctagacacat acgggccata tttagatgac agcatcttat ccgttcattt tttgcgcaca 2897581 gactcttcct atctatgcct tgattatgac gagcatacct tcaaagagct gatttcagcc 2897641 tgcggaagca ttgaagcggt atatgaacaa tattaccgga gtatctattc ttccattgta 2897701 gcatctctcg gcgtttataa gccaaaaaga gtcggtcaca tcacactcgt ccaaaaattc 2897761 atcaagctgt ttccatacag catgtcagag catattcgcg gcctcgtttc tctgtgcctg 2897821 aatgccattg aagaaaacgg aatggagctc gacttcaata cttccggctt aagaaaaact 2897881 tacgctggcg gtatttatat cgaggattgg atgctgaatg aagcgaagca aaagaagatc 2897941 ccgcttgtgt ttgggtctga tgcccatcaa gcgggagatg tcggatatgc gtatgaggcg 2898001 tttttggaac ggtgctagtt ggtgagcgcc acgtctcctg tccggaagac gcttctgatc 2898061 caaatcttga tttcttcaaa atacatttta taaaaatacg gctcgtgcgg ctgcatgtag 2898121 agtacttctg aaatatattg aggctggaga tagggcatca tcaagagaga ttttaattgg 2898181 agaataaaat gaggcagcgg cagcgttaaa tattcacgct gtttttctcc ttcctcaatg 2898241 atcagctgga agatatactt ttccttcatt agatatgtcg acataatttc cctgattaat 2898301 gtggagtcaa ttgtgacttc ccggtagaca aaacgagtta attgacgatg attatgctga 2898361 taggataaaa tatcgaaaac caattgaaga agctgttcct gcgtgctttg agtagagata 2898421 ttgcttgccg ctgtttcaag cgttttgctg tagccttcgt aaaactctga aactaagtgt 2898481 tccatcaagc ctcctttgcc tttaaaatag taggagatgt gcgcaacatt tacatcagct 2898541 gactttgcga tttcacggac agacgtgcca gaaaatcctt tttggttaaa aagcatgaca 2898601 gcagattcaa taattttgtc tttggtgctt actttcatac ggctcactcc ttcctcttga 2898661 tactattcaa gcagaaagcc gctgttcctg taagaactta tcgacaaatg ccggcagaaa 2898721 agccggaact ttgttttata ttatagaaaa agtgagggtt ttccatgttc catgtcgaaa 2898781 aacaatctgg agataaagaa aaagactatc agcttctgct aaaacagctc gaagccatga 2898841 ccgaagacga aacagaccaa atagctaact atgcaaatgc ctcagcactg ctgtatcatt 2898901 cgctgcctga agtcaactgg gcgggtttct attttgccaa agaagaggat ggacagcttg 2898961 tgttaggtcc gttccaaggc ctgccggcat gtgttcggat tcctttcggc agaggggttt 2899021 gcggcacagc gtacgcaaac ggaaaagtgg aacgtattga ggatgtaaac gcgtttccgg 2899081 gacatatcgc ctgcgatgca gcgtctcaat cagaaattgt gcttccgatt cgtgtagacg 2899141 gaaaaattgt cggcgtcttg gacatcgaca gcccagtgaa aaaccgtttc gacgaaattg 2899201 atgaaaaata cttaactcaa tttgccgaaa cgctagaaaa agcgttagcg cagtaatata 2899261 aaagcccaaa actgatatcg ttttgggctt tttttatttt attgagtcat gaatcatcaa 2899321 gcggtttttc ccgctccgtt tcgcgctgta gagcgcttca tctgcctcat gcacaagctc 2899381 tttcagcgac ttttttgttt ctgtcgtcca gcaggagata ccgcaggaaa tggttacctc 2899441 gggtttcgta ttttttctga ccgcgtaaac cagtcgctcg gtaatccgtt tccccactgc 2899501 aaccggcaca tttggcaaat aaatcgccag ctcctctcct ccccagcggg caccgacatc 2899561 atgctttcgg atgttgcttt taatcactga agcgacttga attaaaatct cgtccccagt 2899621 ctgatggccg tacgtatcat ttacattttt aaaattatca atatcaacaa gaataaaaac 2899681 acccttttga tggattttca tgctgtattg aattttttca tctaaatacg ctcgtgaata 2899741 cagttcagtc agctgatctg ttttcacgag atgctcaagg cggtcgcgaa gcattgaatt 2899801 ggttacagcc agtgtcgcgt gatgaatcag cgcctgaaac agcttgtaca tttcaaatgt 2899861 aaaagcgtac agctcctgtt tcaataaaac cgcaaagcct aaaagccggt cgttttgaat 2899921 catcggagca gccatcagcg agccgtaccc cgccttccca aaaacagact ggccattccc 2899981 gatgaaaacc cctttttcac cttcatacag cttttctttc agctcattat aaaaatctga 2900041 cggcttcgct tctttaaaaa atgctgtgct gcctgggagc aatgttaggt tttcaaaatg 2900101 gtctatatga aaaaatccca cttcttctgc ctgaaacgat tctgccattc tcacagccag 2900161 atcattcatt gtatcagtca atgtcagccg ctgattcagg cgtcgtgatg tttcattaat 2900221 caattccaaa tttgcgatgc ttgctttgga ttgttcgtag agctgggcat tttcaaacgc 2900281 ttttcccgcg gcgtttgcta acagcgacat ttcatcaagg caggcatcag taagaaagct 2900341 gtcacccgtt ccttcagcct tcaacacccc gtatgtgccc tgctgtcctt tgatcggaat 2900401 ataggcgaca gattcatttt tccgcaaaat gtctccggac aaatacactt tgagcgcaaa 2900461 ggaatcggat ttttcccctt ccatatacag ctcttttgca ggaatcccta aacattggtc 2900521 ttgatcgtgc gatataaata aagaaaactc aaaaagagaa aatgtgcttg tcaagctttc 2900581 taaaagctgc ttcagcacat ctgtctgatc aagcagtgaa tggaacagct ctgtcatttt 2900641 gtatatcttt ttttggtaga tcgttttgtt atagagtctt tcctgtttca tcgactggtt 2900701 taaaaatgaa gcaaccacgt ccggaagccc ttcaggaatc tcttcatcct gcctgcacgc 2900761 aagatggaaa cgcctgccgg agccgtcctc aatcagataa catgaagcgt ttatttttga 2900821 agcggaaaaa cgcgcttcac catctgccag ttttgtcaca aagtctgatg gtgacggtgt 2900881 aagcgaaaca caaagggttg aaaaataggt ttgaatagcc gaagtcagcc atatgaaaga 2900941 gtcggtgaat gtgacttttt cagatttggt taataaaaaa tcgagcatat gataatgaaa 2901001 ggcggataat tgatctttag tttgttctac catgttttta tcacctaaaa gtttaccact 2901061 aatttttgtt tattatatca taaacggtga agcaataatg gaggaatggt tgacttcaaa 2901121 acaaataaat tatataatga cctttgtgtg aaatattgca gcctttttgt tcagcttcta 2901181 tgttttcatt ttgttcctta tcaataaggt gtatcgtgta actctctgct gctggagcga 2901241 ggatacatga aaacaaaatg tgcatggtcg aatagagcag acggttttta ttttccacaa 2901301 aaataaaacc aaaggaggag tcacattatg gctcgctata caggtccatc ttggaaactg 2901361 tcccgccgtc taggaatctc tcttagcggt acaggaaaag aattagaaaa acgcccttac 2901421 gctccaggtc cacacggccc aggacaacgt aaaaaattat cagaatacgg tttgcaattg 2901481 caagaaaagc aaaagcttcg tcacatgtac ggtgtaaacg aacgtcaatt ccgcactttg 2901541 tttgacaaag ctggcaaact agctggtaaa cacggtgaaa acttcatgat tcttttagat 2901601 tctcgtcttg ataacgttgt gtacaagcta ggtttagcac gtactcgccg tcaagctcgc 2901661 caattggtta accacggtca cattcttgta gacggaagcc gcgttgacat cccgtcttac 2901721 ctagtgaaac ctggtcaaac aatcggtgtt cgcgaaaaat caagaaacct ttctatcatc 2901781 aaagaatctg ttgaagtgaa caacttcgtt cctgaatacc ttactttcga cgctgaaaag 2901841 cttgaaggta ctttcactcg tcttcctgag cgttctgaac ttgctccgga aattaacgaa 2901901 gcgcttatcg ttgagttcta ctctcgttaa tcgttttaaa aacccctgcc gctatgcggt 2901961 cggggttttt ttatcggctt tcgcctcttg ctggccaaca ctatcttgcg cctgctgctc 2902021 ccaatgatcc cgctgcagcc gttcttttgc aatcgtacac atgagattca cgctttagcg 2902081 ctcctttcat ttaaaaggtg gtgattggtc gtgtttgccc tatctaatat actcttttcc 2902141 tttcattcct atgcggtaaa caaaaagatc ctttgccttc agtggcaaag gatctttttc 2902201 ttatttatac gtcacaagga agtatttttt cttcccgcgg cgcagaacag taaattggtt 2902261 ttcgatgcgg tcttcacctg atagggtata atttatttcc gtctggcgtt caccgttaat 2902321 gtaaacagct ccgttttgga tgtcttcacg cgcttggcgt ttagaaggag ataatttaga 2902381 ttgcaccaac acatctacaa gtgaaagctc ttgggtgctg tcaacttcca tagaaggaac 2902441 atctttaaag cctactttta cgtcttgagc agaaagctct ttaatattgc cgctgaacag 2902501 cgcttgggag atgttgatgg cttgctccag cgcctcgcgt ccgtgaacaa gtgatgtcac 2902561 ttcttctgcc aggcgttttt gcgcttcacg tttttctggc gccgtttctg ttttttcagc 2902621 gtatgcttca atttcctctt ttgaaaggaa cgtgaagtat ttcaagtatt tgacaacgtc 2902681 acggtcgtct gtgttgatcc agaattgata gaattcatat ggcgatgttt tttctttatc 2902741 aagccagatc gcgccgcctt ccgtttttcc gaacttcgtg ccgtctgctt ttgtgacaag 2902801 cggaatcgtt aggccaaacg cttttgctcc ttcttcttct gattttctga tcagttcaag 2902861 acccgctgtg atgttgcccc actgatcgct tccgccgatt tgcagtttac agtttttgtc 2902921 tctgtaaaga tttaagaaat cataagattg aagaatcatg tagctgaatt ccgtgtacga 2902981 gatgccggat tcaattcttg agctgaccgt atcttttgcc agcatgtaat tgatgccgaa 2903041 atttttacca acgtcacgaa ggaaatcgat cacattcatt ttgccgatcc agtcaaagtt 2903101 gttcgcgatg acagctgggt tttctgctgc ttcaaaatct agaaatctgg acagctggtt 2903161 tttgattttt tgggaccatt cggatacgat gtcagcagtg tttaatgtac gctctgcttt 2903221 ttttccgctt ggatcaccga tgaggcccgt cgcgccgccc acaagcgcaa tcggatgatg 2903281 ccctgcaagc tgaaaacggc gaagtgttaa aataggcagc aggtgtccga tatgcaagct 2903341 gtctgctgta gggtcaaagc ctgagtacaa gcggattttt tcttcattca gctgtttatt 2903401 taacccttct tcatctgtca tttgctgaat caatccgcgg aaggataagt cttcaagtaa 2903461 gttagtcata agataaagct ccttttttaa ttaaaataaa aaacgcccct tcgtttacac 2903521 gaagggacga ttgattatcg cggtaccacc ctactaataa gagaatgcaa acattcgtct 2903581 tatcactttg cctgataacg gatcaggtcc gttctttcac tactgaaagc ctggccggct 2903641 ttgtttgcaa aagcggttca tgagtgtatt cgatatatcc gtctgtgctg attttcaccg 2903701 gccatcagct ctctggaacg taaggatatt ctacttgtct caatctttac cttttcatat 2903761 gaagctatat catttttaac ataaataaaa tcctgtgtca acgccgcctt ttaatcctcc 2903821 attgttgaca gatctccagc cggcagatta agctcccatg ccttcagcac gcgcctcatg 2903881 atctttccgc ttctggtttt cggaagctta tctttaaatt cgatctcacg cggagccgca 2903941 tgggctgcaa gaccctgctt tacaaatagg cggatctctt ctttcagttt atcagacggc 2904001 tcaaatcctt ccctgagtgc aataaaggct ttaatgattt ctccacgcac cgggtcaggc 2904061 tttccgataa cgcctgcttc tgcaatagcc ggatgttcga caagcttgct ttccacttca 2904121 aatgggccga cgcgctcacc ggaggtcatg atgacgtcat caactctgcc ttggaaccaa 2904181 aagtatccct cttcatccat gtaagcagaa tccccagaca cataccagcc gcccggcatg 2904241 aaatacgatt catacttttc agggttattc caaatggtat gcatcatgga aggccagccc 2904301 tttttgatgg cgagattgcc cattcggtac ggcggtagct cgttgccttg attgtcaacg 2904361 atcgctgcct ccactcctgg aatcggctta cccattgaac ccggtttaat atccatgcaa 2904421 ggatagttgc agatgagctg actgcccgtt tcggtcatcc accaggtatc atggattcgt 2904481 ttgttaaaaa ctttatgtcc ccatctgatg acttccggat ttagcggctc accgacactg 2904541 agcacatgcc ggagtgaagt tagatcatat ttcgcagcca tttcatctcc cgctcccatc 2904601 agcatccgaa aagctgtcgg cgcgctgtac cagacattga cgccaagctg ttcaatcgtt 2904661 ccataccagc tttccgggct gaaacgtccg ccgacgatga catttgtcgc tccgttcagc 2904721 cacggtgcaa aaatgccgta taccgtacct gtcacccagc ctggatcagc cgtgcaccaa 2904781 taaatgtctt cttcctttaa atcaaggacc cactttcctg tttgatattg ctgaatcatc 2904841 gcttcatgga catgcaacac gccctttggc gtaccagtgg aacctgatgt atagtgaagc 2904901 agaaagccgt cttttttatc catccattcg atatccaatc ttgtgctttc ctgtttcgct 2904961 gcttcatcat aattgatgat attcgtgccg ctctcagcct ctcccccgac tacgaagaca 2905021 tgctgcaagt gaggcagttt gtctaccggt attctctcca gcagctcagg cgttgtgaca 2905081 acaacctttg cctcactgtt ttcaagccgg tctttcaccg ctccctccat aaatgcttcg 2905141 aacagcggcc cggcgatggc gccaattttg attgcgccaa gcataataaa ataaagctcg 2905201 ggtgatctcg gcataaaaat aaaaacgcgg tccccttttt ccacatttcc ataccgtctc 2905261 agcacattcc cggctctgtt tgattcttcc ttcatttctt taaatgtgta tttttcatcc 2905321 ctttttgcgt ctttataata aagcgctact ttgttttttc gaaacgattc ggcatggcgg 2905381 tcaatcgctt catacgccgc attcagtttc cctgtctcat gccaagagaa atgtttctct 2905441 gcctcggccc aatcaaaatg ccggtacgtt tcttcatagt tttttaagtt atgatccccc 2905501 tctattgctg gtaacgcttt caagttcatg cccaaacatc cccctttgct gaagttgtca 2905561 caattattat agtatatatt catattcttc tcaattttta aaatataaac catgttgaaa 2905621 acgctttata atttggtatt cttaaagaag gcatgtattt ttgataagaa ttgatgggac 2905681 ggtgaattag tggaacatca taaaacatac cattcagcaa acatcaaaac agcaaccggc 2905741 tctttactga tagaagggcc tgtctctcca gaggatttgg caggttatga gtttcataaa 2905801 gatttaaccg catttcgccc gcctcgcgag cagcatgaag cgctagtcga cattgcaggc 2905861 cttcccgaag ggcgcattat tattgccaga gacggccgaa ccattgtcgg ctatgtcacg 2905921 tatttatatc ctgacccgct cgaaagatgg tctgaaggaa atatggagga tttgattgag 2905981 ctcggagcca tcgaagtagc gccggactat cggggatgcg ctgtcggaaa gacgctcctg 2906041 accgtcagca tgatggatga acaaatggaa aactacattg tgatgacgac agaatattac 2906101 tggcattggg atttaaaagg gatgaaaaaa gatgtgtggg aatacagaaa gatcatggaa 2906161 aagatgatga atgcaggcgg attggtctgg tttgcaacgg atgagccgga gatcagctcc 2906221 caccctgcaa actgtctgat ggcccgcatt ggaaaaaacg tcagccaaga atcaattgag 2906281 caatttgaca ggctccgttt ttatcatcgt tatatgtatt aactgacact gacaaagggg 2906341 aaaaaataat gattgttgag caaatcatga aaagagatgt cattacatta acgaagacgg 2906401 atacgcttga aacagcaata tgcaaactga aggaattcca tatcaggcat ctgcctgttg 2906461 tagatgaaga acgacacgtg atcggcatga ttacagacag ggacatgaaa caggccagcc 2906521 cgagtatttt tgaagaaaac aaacgaagcc tatttctcac acgaagcgta gattcaatta 2906581 tgaaaaagga tgttgtctgc gcccacccgt tagattttgt cgaagaaata tcagccgtgt 2906641 tctacgagca tggcatcggc tgcctaccag tggtacacca tcaaaaatta ataggcattt 2906701 taacaaaaac cgatttgctg cggacgtttg tcaaattgac aggcgctgac cagccgggct 2906761 cgcaaattga gataaaagta aacgacatca ccaaaagcct cgctgagatc agcagtcttt 2906821 gccaagacct tcaagtgaaa atattaagcg tgcttgttta tccgcatgac gatcccggtg 2906881 taaaagtgct tgtcttccgt gtaaaaacga tgaatccgct gccgtttttg caggcattac 2906941 aaagaaatgg acaccacgtc gtatggccgt cagagcaaag ggatctgcta tgagagacag 2907001 tgtatttatc tattctccat cctaccaaac ctatatgttt catcaggagc atccctttaa 2907061 tcagcagcgg gttctgttaa catatgattt gcttaagacg atcaatgcct ttgatgatgg 2907121 agacattgtc acccccagac tcgcttcaga agaggagctt tcccttgtcc acacggacga 2907181 ttacattcag gccgtaaagc ttgcgggcgc cggaaagctc cccgctgaag aaggagaaag 2907241 ctacgggctc ggcactgaag acacacccgt ctttgccggc atgcacgaag cggcatcact 2907301 cttggtcggc ggcactttaa cggccgcaga ctgggtcatg tcaggacaag ccctgcatgc 2907361 ggcaaacctt ggcggagggc ttcatcacgg ctttcgcggg agagcatcag gattctgcat 2907421 atacaacgac agcgctgtgg ctattcaata tatccagaaa aaatatagcg ccagagtgct 2907481 ttatattgat acggacgccc accacgggga cggtgtgcaa tttacatttt acgataatcc 2907541 tgacgtatgc acgctgtcca ttcatgaaac aggaaggtat ttattccctg gaaccggtca 2907601 gatccaagaa aaaggaagcg gaaaaggata tggctattcc tttaatattc cgcttgacgc 2907661 ttttacagag gatgattctt ttcttgaggc ttaccggaca gcagcttcag aagtcgccgc 2907721 gtatttcgag cccgatgtca ttatcagcca aaacggcgcc gatgcccatt actacgaccc 2907781 gctgacgcat ttatcagcaa caatcaatat atacgaagaa atcccccgtc ttgcacacac 2907841 tttggctcat caatattgcg gagggaaatg gattgcagtc ggaggcggcg gatatgatat 2907901 ttggcgtgtc gtgccccgcg cctgggccag aatatggctt gaaatgaagg gaattgaccc 2907961 gggtcacgag atcccgccgg aatggattgt taaatggcaa aaacaatgcc ccgtggccct 2908021 tccgtcgagc tggagcgatc cggctgattt atatcctccg attccccgca agcctgaaat 2908081 tacagaaaaa aatgcccaaa ctgtcagcaa agcattatat gcgatacgtt ctgaacagca 2908141 aagaacaaag taaaaaacga cctttacgaa gaggtcgttt ttgatttttt aatcactatt 2908201 tccacacgcc gattttcctt catgtgttca tttgtcttgt tatcctttac tggctttgta 2908261 tccgcataac cgacagcaat aaagcgcttg gagggaagct tctctttaga cgtgaagtat 2908321 tgaatcactc cacttgcccg tgctgctgat agctcccagt tcgacgggta tcggtatgtc 2908381 gaaatgtttc ggctgtctgt atgtccctca acctgaatgt catttggaat tgtttgaaga 2908441 agaacggcaa tttggtgaag aagtgtttcg gcatttttca gcacctttgc ctcacctgta 2908501 tcaaacagca cagcctcctg aagaacgagc acgacaccgc gttcatcccg tttggctgtc 2908561 atttgggcct tcaaatgatt gtcttttata tatgtattta ctttcttgag aagctgatcc 2908621 tgctgatcct cttgcttctt cgtatcagat ggggatgtat tctttttttc tatggatgtt 2908681 tggtccggct gaagcccgtt gccttccttc tggatcgagt ccactgccgc tttgaatttt 2908741 tgcagatcga tttgggacat cgaaaagagt aaaataaaga acacaaggat caaggtgatc 2908801 agatctgtaa aggttaccat ccagctggat gaagattgac tgttttttcc gcttccattc 2908861 cttctttcaa aacgttctct tctaagcttc atgtacagat cccttttttg tttttacttg 2908921 ttttggctgc ttctgccatt cttcccgtga gctgaaaacg accagctggc tttcaaggtt 2908981 gcgcgggttt tttccggatt gaacaccgat aatcccttcc accattacct gcttgatgaa 2909041 aatttcactt tctgttttct cttcaagctt agccgcgatc gggttgaaga ccatatttgc 2909101 cagtaatgaa ccatataaag tcgtcagaag cgcaatggcc atgtttggtc cgagcatatg 2909161 cgggtcgttt aagtttttga gcatcagcac aagcccgacg agtgttccga tcattcccca 2909221 tgccggagcg aattctcccg ctttttcaaa aactcgccgc ccttttcggt gccgttcctc 2909281 cattgctgcg atttctgaat ccatgacgag ccgaatcgtt tcttcatccc agccgtcaat 2909341 cgctaaaagc agcccttttt tcaagaatgg atctttgatt tcccgagcct gatcatccaa 2909401 tgataaaagc ccgtgttttc gcgcgtgatc ggaaagggaa acaaaggttt tcacaagatc 2909461 tttcacattg tcttcctggc ggatgaatgc ctgctttaac acagagggcg cttttttcag 2909521 ctcacttggc ggaaaactga taaaaacagc ggcgcaaagt ccccctgtta cgatgaagaa 2909581 agaggtcaga tcaagaaaag agcggaaacc gcttactccc gatcctgaaa taatcccgat 2909641 aacaataata atcgttccta acacaaatcc aacaggtgta agataatcaa aacgtttcat 2909701 catttctccc catgaaaaaa gcaagaattc accataaagg tgaagcttgc tctttgtttt 2909761 tcttatgact tggttgactt tctaagctct atacggtgcg gcagttcgac gatatgctct 2909821 tcaaccggct ctttattcat gagcttcgtc agcagtctca tcgcaacggc gccgatatca 2909881 tatgtcggct gaacaactgt tgaaagctga ggacgaacca tgaggcttaa tcttgtatta 2909941 tcaaaaccga taatgtcgag atcctccgga atggataagc cctgatcctg agcggcatgg 2910001 ataatgccga gtgccatttc atcagttgca gaaagaatgg ctgtcggttt tttatccagg 2910061 ctcatcagat gctgcagtgc ttcgagtccg gaatcatatg tgtaatcccc ttcagctaca 2910121 aattgttcat taaacggaag gttcgcttct tcaagcgcac gtttgtagcc ttggagtttt 2910181 ttcgaacggt tgatcggttc tgccattggt ccggaaacga acgcgatgtc tgtatgtcct 2910241 ttatcaacca aaagcttcac ggcatcataa atcgcctgtt cgtaatcgat agcgactgac 2910301 ggtgtttcct cctgctcttc tacagaagcg gcaagtacaa tcggcactgg agaacgctta 2910361 aattccgcca catgctcgtc cgtaatgttt ccgcccataa acacgatgcc gtccacttgt 2910421 ttgccgagca ttgtgtttaa caagtgcagc tctttctcca tgttttggtc agagttgctc 2910481 aaaataatat tgtatttata cattgtcgcg atatcttcaa ttccgcgcgc aagctctgaa 2910541 tagaaaatgc ttgagatatc gggaatgatg acacctacag ttgttgtttt tttacttgcc 2910601 agccctcttg ccaccgcgtt tggacggtaa ccgagacgtt caatggcttc caagactttt 2910661 ttcctcgttg tcggttttac attcgggttg ccgttcacga cacgggaaac ggttgccatg 2910721 cttacattag cttctctcgc tacatcgtag atcgtaatat tgctcatcct aaaaccactc 2910781 cttttactgg atacacttat ccttatctat agcataaaca ctttatgtag agaaatgtca 2910841 taatgtccga atttatgtcg tttatgattt gtaagcgtaa gtcagtagtg tacattattt 2910901 ttcattattc atcaaattta attacttctc atgaaattat acacgttttt atagatgatg 2910961 aaaacgtata cttggttttt ataactaaat aaacgagaaa gcataaaaaa aggccgcagg 2911021 cgcggccttt tggattgttc aattaagcgt tgactttcac cattggcttc agttcattca 2911081 gccatttttc gaattcagga atcgccattt gctgagcaga gtcagaaagt gcgactgacg 2911141 gatcagggtg aacctcagcc attacgccat cagcaccgat cgctaaagcg gctttagctg 2911201 tcggaagcaa gaggtcacgg cggcctgttg aatgcgtaac atcaacaaag actggcaaat 2911261 gcgtttcttg tttcaaaatc ggcacagctg aaatatccag cgtgtttctc gttgctgttt 2911321 catatgttct gattccgcgc tcacaaagga taatttggtc atttccttgt gacatgatgt 2911381 attcagcagc attgatgaat tcagagatcg ttgcagcaag accgcgcttc agaagcactg 2911441 gctttttcac ggcgccggcc gctttcagca attcgaagtt ttgcatgttg cgcgctccga 2911501 tttgaatgac atcaatgtag tccagcgctt cttcgatatg agccggagtt acgatttcac 2911561 tgataaccgc cagatcaaat tcatccgcta cacgttttaa aatttgaagg ccttcaacac 2911621 caagcccttg gaaatcgtat gggctcgtac gaggcttaaa ggctccaccg cgcaaaattt 2911681 taatcccttg ttttttcgca gctgcagcga cttcagctac ctgctcatag ctctctaccg 2911741 cacatgggcc gacaatgaat ctttgctggc cgtctccgat tttttcgcct ttgatatcaa 2911801 caattgtatc ttcaggtttt ttcttgcggg agacaagcag cgctttgctg tgatcttctt 2911861 cctgaagctc taaaccggct ttgaatatct ctttaaaaat gtgctggatg gttgaatttt 2911921 cgaacggccc gtcattgttt tcaatgatat tgtttaacat tgtgcgttct ctgacagggt 2911981 caaatcggtt gacaccctgt gcttccttcg ctttaccgat ctcttttaca acattgccgc 2912041 gttcgttgat taattttaaa atttgtaggt ttaattcgtc tgctttctgc cttaaaagct 2912101 ctaactctgt gttgctcatt tttttcatcc tttccctgca cattcatttt ttattttgta 2912161 gttatcatgc atcttactat aagtaattcc aaatggaaat actgaaatac aaaaaatttt 2912221 ataaaaactc tactttatta cccaaacgct tttaagtgat aaagtaatct atgaagctat 2912281 cctacatgat gtgagggcaa tgttcaaggg ttttttacaa aaaaaagcgc cagatgatat 2912341 ctggacgctt ttttctatga caaatgctgc tcaatagcgg cttctgtaat ttgtgaatgt 2912401 gaggtatgcc atttcacttc accgttctgg atgatgaata tctgagggct ttcatgcttg 2912461 accccatatg tttctgcaat gaaattggac agcggccggg cttcttgtac ttgaagatag 2912521 taagccggca catcctcatg ctgatttgca aaggcatcaa actcatgaaa tgctgcctgg 2912581 ctgatcgggc atgtggtgct gtgtttcaag aagacgaaaa cgccttcctg ttctgcaatc 2912641 cgtttaaatt cttcctcaga ttgaataagc tgtttagcca tgactcaagc tcttccttcc 2912701 ctgctcagcg attcaactgc tcagcctgtt tttgtgcatc tttcagttcg tcttttacat 2912761 cttctttcgt ctggaggact tgatcttttg tttcatcagc tgcctgcatc gcttcttccc 2912821 tcatatcttg cattgcagtc gatgaatccg ttttgtcaga tttggaacgg tctctcaaat 2912881 cctttacctt gttcatgatc tgtccagact gatccgctac aagctgtgtg atgttggaag 2912941 ttttgtcttt tgcgatgctg acatattgcg tgcctttttc cttcgcatct gccgtcattt 2913001 tatcagtttt gtcccgtaag gcaacagcct ggctgccgag atcgtcgcga agttctttgc 2913061 ctgatttagg cgctagaaaa agagctgtag tggcaccgat gattcccccg attaaagttc 2913121 cgattaaaaa atctttacta ttaattccat ctttgctcat cattattcct cctcttagta 2913181 tttttttctc ttacagggct gattttttct tttgcttcca tttctcccaa atttccattg 2913241 ctgcttgact ccaagtgaca acttgattga tcttatcttg attctctcta actgatgccg 2913301 atacagaccc tgccgcttgt ttcatggatg tattgaactg ctgtacagaa gctcccactc 2913361 cttgaacagc atgaacgacc gtgttcagct tttctgattt ttcctgaata tcttcagcca 2913421 ggcggttggt cttatgtaaa agctcggctg tttcagttgt gatgcccttc atttgtccct 2913481 ccagcccttc aagagtggat gcgacgtttt ttagtgtcag ctgcagtgac ttcaatgttt 2913541 tagacaagta gatcactaat acgagaaatg caactgcgat gagtgcaacg ctcaaataaa 2913601 gaataataat catctcaaac ctccttgctg caggatatac tgctgtttac ccgttttctt 2913661 caatcataaa catgtgtact gggctgtata catactattc tccgttatgt aagaaaatcc 2913721 tttaataagc tttcccatca gataaataaa aagcagtgag atcactgctt tttattatgc 2913781 catgacgttt tcgtaggctc tcatatattt ttggatatct cctgctccca tgaagatgag 2913841 aacggcttta tcatgagctt ttaaaacaga tgtgtcatct tcttcaatca gcttggcatt 2913901 atgaattttt ccctggagat caccgatcgt cagctttccg gcattctcac gggctgagcc 2913961 gaaaatatcg cataaataca cacagtcggc gccgctcagg ctttctgcaa attcgtcaag 2914021 gaactgctgc gtccgggtaa atgtatgagg ctggaatacc gcgacaattt cccgatcagg 2914081 atacttctgt cttgccgcct cgattgtcac ttttatttct gtcggatgat gggcatagtc 2914141 atcaatcagc acttgatccc caagctgctt ctcattgaat ctgcgtttga cgcccccaaa 2914201 ggatttgaga gcatgcttaa tgatgctgga atcaatttct tcataatggc ataacgcaat 2914261 gaccgccaat gagtttaata cattgtggtg gccgtacgca ggaatataaa acgtatcata 2914321 gaacgtattg cggacaaaga catcaaaagt tgtcccttcc gtgcttttta cgatgtttct 2914381 ggcttgaaaa tcattttctt cccccgtgcc ataatacaca accgggacgt tcgcatggat 2914441 tttcggcaga tgctcatcgt ctccgcaggc aataatgcct ttgttgactt gaagagccat 2914501 ctcttggaaa gcgtcaaata catcgtcaat gcttgagaag taatcagggt gatcaaaatc 2914561 aatattcgtc ataatcgcat aatctggctg atagcttaag aaatggcggc ggtattcgca 2914621 cgcttcaaac acaaagtatt cgctgttttc atttccctgg cctgttccgt ctccgattaa 2914681 gaaagacgtc ggttttgcgt tttggatcac gtgagccagc agacccgtag tcgacgtttt 2914741 gccgtgtgcg cccgtaacgg caacactcgt gaattttttc atgtagtcgc ctaaaaactt 2914801 atgataacgt atcaccggaa ttccctcaga catcgctttt tctatttcag gatgcgtgtc 2914861 tgggaatgcg tttccggcga tgactgtcat gccgggttta atattttccg cgctaaaagg 2914921 aagaatcgta atatttcttt tttcaagcgc tgtttgcgta aaaataaatt tttcgatatc 2914981 cgatccttgg acagtatatc cattatcatg aagtatttgg gcaagcggac tcataccggt 2915041 cccttttatt ccaacaaaat gataaacagt cataattgta cctccaacaa acgtctatct 2915101 gttccccagt atatgacgct catttcaatt tgcgaccgcg gcggctgaaa agcctccctt 2915161 agcggcgtat tttatatgtt ttgttatgtt tagtatcagg ttatttcttt ccgattaaac 2915221 ccagatatca agatttgtct atgcacagct gctgtaaagc ggcatagctg ttaaatgctc 2915281 taaacactat cataccatgt ttggtgtgaa aatgaaccca tattattcgt ttattaaatc 2915341 acttgctgtg atcagcacct ctcgaggctt gcttcctttt gcctcagaga tcatgccttc 2915401 cgcttccatc atgtcgatca gccttgccgc acgattgtaa ccgattctga atcttctttg 2915461 caggcttgaa gtgctcgcac tgttttgctc tacaacaaac tcacacgctt cgtaaaacag 2915521 ttcgtcctct tctttcaggg cagatccttg tcttacgagc tcttcttgtt caaataaata 2915581 ggtcggcggc atttggcttc tgacgtggga aacgacgcgg tcgatttccc ggtctgacac 2915641 aaagttacct tgcagacgaa ccggttttcc cgagccgttt tccaaaaaga gcatatcccc 2915701 ttttccgaga agcttttctg caccggctat atcaataatt gttcgggaat caacctggct 2915761 tgagacagaa aaggcgattc tcgttgggat attcgcctta atcagacctg taatgacatc 2915821 gactgacgga cgctgagttg cgacgagaag atggataccg cacgctctgg ctttttgggc 2915881 gatccgcgca atgctttctt ccacatcgtt tggagccacc atcatcaaat ctgcaagctc 2915941 atcaataatg acaactaaat acggcagctt ttcacccatt tggtgttcag cggttaattg 2916001 attaaagcgg tcaatgtcgc ggacacctga atgggcaaaa agctcatagc ggcgctccat 2916061 ttcctcaacg acccatttca aagcagccgt agccgcttta gcatcagtaa tgaccgggct 2916121 gacgaggtga ggaattttat tgtaaggggc cagctctacc attttcggat caatcagcag 2916181 cacctttacc tcactcgggt cagctttata aagcaggctt actaatattg tattgatgca 2916241 tacgcttttt ccggagcctg tagcgccggc aatcaagcca tgcggcattt tcttcaagtc 2916301 gataacaaca ggatttcccg aaatatctaa tcccagcgca gctgtgagcg gtgacttgct 2916361 tgtcctgaaa gctgagctgc gaatcatttg gcgcaaatca accaccttgc tcgtgcggtt 2916421 cggcacttca attccgatcg tgtttttccc cggaatcggc gcttcaatcc gaatatcttt 2916481 agctgagaga ctgagtttaa tatcatcgga caagttggtg attttattca cctttacacc 2916541 cggttcagga tgcacttcaa atctcgtgac agacggaccc tgggttacat ggaccacatt 2916601 ggcgcggaca ttgaaatttt tcaaggtcaa atcaagaagc tgacgctgtt cttcgatcca 2916661 cgcagtatca tcttgaacct gcgctggcgg gacatcaagc agtgcaacat tcggaaatac 2916721 atagctgccg cggcgctcct ctgctttttg ctgtttatgc gtatctcttt tcagcatcat 2916781 cacattaaaa ggaacggatg gccctttttg agaagatgcg ctttgttcag tccttttctc 2916841 ctgtacacca ggcctttttt tcggctcttc tgaagcttcg cgaggtttgt ctgcgcgaat 2916901 ttcctgccgg ttttcaagag ttgcagtaga cgatttggaa ccctgctcca tgtgttcagt 2916961 tttctcaagc tctgtatggc tgtctggctg aacatctatc ttcgtttcct gagcctctcc 2917021 cagggtgtca taatgattat ttattatgct ttctgatggc tcttctgatt cttttgccac 2917081 agtttctgct tgagccagag cctctgatga atactcatga tcagtaaata aaggctcttc 2917141 ctgacgaatg tccatttgtt cttcttgaac gaacggggac tcagcacctt ctgccgcgtt 2917201 ttcatgatga ttgtatactg ggctgtctga cggctctttt gctttttcat cctcagatac 2917261 tgcctctgtc tgagattcag gagctgtttg ctcttcatca agttcagcgg agaaaacagg 2917321 ctcttcaaat ttctctggct gctgctccct ttgttcttcc tcagccgttg caggctcttc 2917381 gcggcctact tcactgtctg aaagcccttc agccgccgta tctgtgagca tctcaggcgg 2917441 tgtttgctct tcggcttgtt cagctgggaa gaaaggctcc tctttttccg gctgttgaac 2917501 gcctgactca aatggcactt tgttacctga cggctcggct ggccgtttcg ccagcgcctc 2917561 atcatgctcc gtatcctttc tgtttaaaac gccagaaggc tgtttttcaa attgggtatc 2917621 cgggaagaaa ggactttcta ttttggaatg cgcctgtgtg tctgaagcag gatagccgcg 2917681 ttcacgttcg atctcttctg acagcagtgt taccttctct tttaccgatt tatccggttc 2917741 gttcaatgtt tcagaaggct ttttcggcac atccttttta acagatggtt tttgattgaa 2917801 tccatagaca ggcgaaggga tatttgtcgg tttaaacggt ttcttcgccg gctctgctgc 2917861 ttgatatgta tgctgctctt cttcatttct gggacgctct ctgtaaggtg cagcacttgg 2917921 acgaggcgcg gatttcggtt cgtccgatgg tgtgcggcgc cttctcaggt catgattttt 2917981 gtatccgtca ggcacgactg gaaaacggaa tttgcctttt ggatattcat aatatatttt 2918041 aggatcttcc aatcttttta attgtccttc aggatgatgt acttcttgtt gctgcggaat 2918101 ttgagcgggt tttgtctccc gttcagcatc ctcttcgctt tcgcctaaaa acaaatcaaa 2918161 aaatttatga agccaactca taatttatct ctaactccct tatagttttc tgggacggtt 2918221 tttagtatac cactgctggt cggcccagaa aagattaagc tatcagcaga aacaaagccg 2918281 ctaaacaagg gcttagcggc ttttcacatg attcgttttt tttggcggat ttatgggagt 2918341 ctaaaactga aatgcgtctc ccgcctcata gtctccttct aacacaagga ttcctttttc 2918401 agcaggggca tccggcaaat caagctcttt cgctgagcag atcatcccgc ttgacggaac 2918461 gccacgaagc tctgcatcct taatgacaag tccgctaggc atcacagcac cgactttggc 2918521 aacgacaact ttttggcctt ggtcaacgtt aggcgcgccg cagacgatct gaagcgtttc 2918581 ttctcctacg ttgactttac atacgcttaa tttatccgca ttcggatgtt tttcttttga 2918641 ttctacataa cccacaacaa acttcggaga taaatcaacg actaatgttt cttcaacgcc 2918701 gtttctgttt aaaatctcat tcacatcttg cacgaatgtt tctgagagcg caacagggcc 2918761 gttttcatca atggtcaagt aagaagacgc attgaaaatg ttgaagcccg ttgtttcttt 2918821 tgtttcgtta ttgaaaattt tgacgacgtc gccgtgtttt tcatagccta attgttcgcg 2918881 tgtcacatct tgaagagaga tcaggagcgt gtctcccaca ccttctttat tataaaaagc 2918941 gttcataagt aaaaatcctt tctaatcctt tttcggacgg cttttcgcca ggataaacac 2919001 cggttccagc tttccttcat tgtacaaaaa tgatagggcg gtaatcggga cggtgccgcc 2919061 tgcaaagaag ctcatcgaca tttgtcctag aatatcatac cccgattcat tccggatgtc 2919121 agcaagaatc aaaacgtcct gatgaggaac agagatcgcc agctcacctt ctgcatgctg 2919181 cttatactca tttaagatcg cttcgttcaa aatccggctt gcgtcgtatc cgtcgtttgc 2919241 cctgaagaaa taaaagtaat tgccggcaac cgtatcctct ttgacaaccg tcggcaggga 2919301 acggagatta aatgcggccg tctctctgat ccgctctttt gtccagtttt ctttctcaag 2919361 catgcgctgg tcaattaaac ggtaggtttt cccgagatct agcgcgtaat aaattcttgt 2919421 ctctgcggta tgatcgtcat aaatgagcgg gatatcttcg ctggacttgt ccgggaagga 2919481 agtcgagcgg atgaccggat aaatgcgagt ttctttcccg gtcatttcct gagccttccc 2919541 ttccattgcc gtcatcgctt cggagacata gtacacgatc tcatcaatgg cttcgtcttt 2919601 tttcagttcc cattttgcaa taatcggcgg caaatcgagt gtaatccctt ttttagtcgt 2919661 ttgatcctca acacggaggg tgtctttttc tctgtcaaac agaaaggagc gattctcgtg 2919721 ctgaaggcgc tgcttcagta tatctgacag cttccttgag gtcattttca aaccgatgtc 2919781 ctcctttacg ctttagcgag agagtctgtt aaaaactgtt caatttcttc ttttgttttg 2919841 cggtctttgc tcacaaaacg atttacttct tttccttcat taaacaccac aaagcttggg 2919901 attccgtaaa tttcccactc tgcacatgta tcaatgaatt tgtcacggtc tacgtagtag 2919961 taggtgaatt cagggaaatt cgcttccagt tcaggcagga aaggctctac aaaacggcaa 2920021 tccgggcacc aatcggccga aaacataaat acagaccaat catcctttac cgctttttcc 2920081 agctcttgag ttgattcaat ttttttcatt tcatatccct ccagttgttt atgttcttac 2920141 atgtttttta tcgatactcg tccatttgga tcataccaaa ctgcttgagg caaaaccact 2920201 tatatgcaac gaatgaatat gtaagattgg ctttcccatt atcattatca tattttattt 2920261 gcattatcaa gctcgtttcg tttaacatcg tgtacatgag ggtgaaattt acagatggat 2920321 atacataagg agggattttt attatggagt ttatcgtcta tttagcagga gaaatccaca 2920381 gcaattggcg cgaggaaatt aaagaaaaaa caaaatcact gaagctcccg attacgtttg 2920441 ttggcccgat ggagaatcat gaccgctcag acaatattgg tgaagaaatt atgggcgtac 2920501 agccaaatgc cgttttaaag gatgacaaag cctctgacat caacaacttc agaaccgccg 2920561 tcctgatgaa taaagcagac tttgtgatcg ccctgtttgg cgaaaagtac aaacagtgga 2920621 acacggcaat ggatgcatca tatgcgatcg caaaaggaaa acccctgatt atcatccggc 2920681 cggaatcgct ccaccatcct ttaaaagagc tttccaataa agcgaatatt acggttgaaa 2920741 ccgttaacca agccattaag gccctttcct atctatttga aacagaataa gaaaaaagct 2920801 tgtcgatccg ggcttactgc tcgttcaaca agcttttatg aaacctacat attttcttta 2920861 atcgcatcca ctgtctgctt atcgcaggct gttacaagtt tgatgagcat ttctttagca 2920921 gcagcataat catcaatatg aatgatagta gcgtttgtat gaatatagcg ggaacatatt 2920981 ccgataaccg ctgacggcac accgctgttc gaaatatgaa ccttgcctgc gtctgttccc 2921041 ccgccggata caaaatattg atatggaata tcatgcgttt cagccatatc aagaacgaat 2921101 tccctcattc cgcgatgcat gactgtcgtt ctgtcaagaa tgcgcagcaa aaagcctttt 2921161 ccaagctggc cgaattcatt tttgtctccg ctcatatcgt ttgccgggct ggcgtcaagg 2921221 gcgaaaaaca agtccggttt aatcatatga gaagccgtct gcgcgcccct tagccctact 2921281 tcttcctgaa ccgttgcacc cgcatagagt gtattcggaa gctctttacc gtgtaattcc 2921341 ttcagaagtt caatgcttaa gccgcatcca tatctgttat cccatgcttt tgataaaatt 2921401 ttcttttcat tcgccatcgt cgtaaacgga caaacaggca cgatctgctg tcccggtcta 2921461 atgccgattt tgatggcgtc ttccttatca tccgctccaa tgtcgatcat catgtttttg 2921521 atatccatcg gtcggtttcg ctgcgcatct gtcaataaat gcggcggtat gcttgaaatc 2921581 acacccggaa ccggcccgtt atctgtttga atttcaaccc gctgcgcaag caaaacttgg 2921641 ctccaccagc ctccgagcgt ctggaatctg agcagcccgt tgtctgtaat ggatgtcacc 2921701 atgaagccga cttcgtccat gtgcccggct accataattc tcggtgcgtc ctctgcgcct 2921761 cgtctgactc cgaaaacact tcccagtctg tcctgaacga tgtcatctgc atatttggct 2921821 agctcctgct tcataaaagc acgaacctga tgctcattgc ccggcgcgcc gggaagctgc 2921881 gtcagtgttt ggaaaagcgc tttcgtttct tgattcatgt tttcccctca tttctatgta 2921941 gtccttttat tttattagaa acaatgaagt tttccaagca ctctgaccca atctgctcga 2922001 tcagccgcgt attgcttaac aggatttggc tgtttctgta taatgaaaag tacgatcaac 2922061 caggaggtgc tttattttga aattgcgtca tcttctttta ggagcaggac ttggaatttg 2922121 tacggctgtc gttgtgagac aatatgtgat gaagccttat atttcttcag aaaaagcgct 2922181 tcgaattgta aaatctgctt ttaagcagcg gggcccgatt gacggatcat ggatttacac 2922241 ccagccggag ccctacaata ttaacggaga aacggtacag gtatacaaaa ccggcattac 2922301 acgatcagct ttcggagaat tagaacagta tgaagtcatg gtggatgcga aaacgggaga 2922361 aattgttgat gtcattgata caatcgcctc ttaacaccgg acaagcaaaa aatagaagcc 2922421 gctgcctatg cagcggctct tttttattat atcgcgcgaa tcggtttgta taccggatac 2922481 cacatcgcat cctgcactgc ctgtataatg tcttcaggct cttccgtagc gacgccttcc 2922541 ttcattgcgg tttttgcaac ttcaacagca acggttgccg aaacagtgcg caaatcttca 2922601 acttttggaa gcatcggcgc cccaggcacc ccgacattga ccatacctgc gattgcccgg 2922661 gcacatgctt caaacatgcc gtcggtaatt aattttgatt ttgtaacaat cgttccaaga 2922721 ccgagaccag ggaagacaag cgcgttgttt gcctgcccga tatgatacgt aactccgtta 2922781 tattcaactg gcgggaacgg gcttcctgtc gtgatcagcg cacggccttc tgtccattcg 2922841 attaaatcct ccggctttgc ttcagaaaga gttgtcggat ttgacattgg caaaatcgcc 2922901 ggccgtttca catgtgacgc catttctttt acaatttctt cagtgaaagc gccggaaacc 2922961 gtagatgtgc cgatcaggat cgtcggtttc gcctgccgaa ccacttcaag aagatcaatg 2923021 cctccgccgt ctccgttccg ctgataatcc ttcacttcat cagccgaacg ggcatacggc 2923081 ttttggaaat caagaagctg atccatatca tctgttaaca gcccgttcct gtctatgcac 2923141 cagaagcgct tgtatgattc ttcttcactc agtccctcgc gcaccaatgc ttcccgcagc 2923201 tgttcggcaa ttccgattcc tgccgttccc gctccgaata taacaactct gtgatctctc 2923261 agcggaactt tagacgcttt tgcacaggat aagactgcgg ccaaagaaac agcgccagtt 2923321 ccttggatat catcattgaa ggtacacact ttatctttat agcgtttcaa aatgcttcgc 2923381 gcgtttttcg ccccgaaatc ctcccaatgc agcaatgcat tcggaaatgt ttctctcgcc 2923441 agcgcaacgt agtcgtcaat aaattggtca taacgttccc cgcgcactct ggaatgctgg 2923501 ttgccgacat aaagcgggtc gttcaagagg ctctcctgat ttgtccccgc atctaaaaca 2923561 acagccagca ctctgctcgg atcaatgccc gcagccgctg tataaaccgc cagcttgcca 2923621 atagaaattg cgattcctcc gacgccccag tcaccgattc ctaaaattcc ttccgcatca 2923681 gttgcaacaa ttaaatcgat cgtatcgctt tgatctttat actgtttaaa agcttctttc 2923741 ataccgtccg ggtcatcgat tgacagatag agccctcgtg gttttctgta ttcatggctg 2923801 tatctctgaa ttgccgttcc gactgtcggt gtgtagacaa tcgggagcat ttcccctaaa 2923861 tggtcattta acaggcggta aaacagcgtt tcattccgat cgtgcagcgc cgttaaatag 2923921 acatttttgc tcaaatcgtc aggctgtgcg gaatattgtt catacgctct tttcgcctga 2923981 tcatcaattg ttaatacctt gggcggcaga aagcctttta aaccaagttc ttttctttct 2924041 tcctcagtaa aagcaacacc tttgttcaaa aaaggaacag agagcacttc aaggcctctt 2924101 aatgttgttt gaatgtctcc ttcgtttgtt actctgaatt gtttcaccct gcctcttcct 2924161 ttctgagcat aatagtacta ggtttgcatt attagccgga aaacatgcag ggtaaacata 2924221 aaaatatgct atcgcttcat tcgcttaact gactttttga tgcttccgtc ctcctcccat 2924281 tgaagggcgc gatactcggc atcatggtaa aaaataaacc aagcatcttt ttctgctgcg 2924341 aacgcctgcc atttctgctt ttgcgggata gaggtcatcg gataatcatc gtaagccagc 2924401 acccatagcg gattgcggtg ggcatgtgtc ggcatcagat ctgccatatg tacggcagtt 2924461 tcacccgcat cctcgcatat caggacactg tgtccgtcgc tatggcctcc ggtgtgatgc 2924521 attgtaatac cctctgtgat cgttaaggtg tcttcaaagg ttttgacttg gccagctaca 2924581 gcctcccaat tttctttcca atacgtattt ttcgacctga tattcggatg gcgcatttcg 2924641 tcccattcaa cagctgatgt ataaatcact gcattcggaa agacagagac gagccgttca 2924701 ccttcatatt ccgttaaacc gcatgcatga tcaaaatgaa ggtgtgtcat tgcgatcaca 2924761 tctatatcgg caaccgttaa tccgagtgca gctaatgagg gtttcacatt cgactcttgt 2924821 gtcacgccat agtttcgttt ttgtttatca gtcagcttgc cgtacccaat tccggcgtca 2924881 atgatgatat tgagcccatc cttttgaatc aaaatagggt ctgttcttag ttcaatctgg 2924941 tttttttcat tgactggata ttttttagac caaagcggct ttggcacaac gccgaacatg 2925001 gcgcctccgt ccatatgcgt cacgcctccg tcaagccagg tcaacgtgat gtttccaatt 2925061 ttcattgttt ccattttcac ccccccctat catcatggta gcaaacggcc cataaaaaaa 2925121 acagactcct gtcagagtct gtctttacgt tctccattca acctcagccc gatagatcgg 2925181 ctggccgagt gcagagaatt tttcttcata ttctgtcata atattgcctt ccagattgct 2925241 gttatgcaaa tcgagactga cgtatgtcag caggaggccg tactcagaga agctcttcaa 2925301 agagtactca aataaacctc ggttgtccgt tttaaaatga atcgatccgc ctttgcccat 2925361 tacttcttca tattttttga ggaagtggga atatgtcagg cggcgttttt catgccgttt 2925421 cttcggccaa ggatcagaaa agttcaagta gacccgtttc acttcccccg gctcaaacac 2925481 atccgtcagc gtgtccgcat ctatattcag aagctttaca ttctgcgctt cgctgtcttt 2925541 tactttttgg acggctgtca cgatgacgct tttaaataac tcaataccaa tataattgat 2925601 gtcgggattt tgtttggcca taccagaaat aaattggcct tttcctgtac caacctcgat 2925661 atggatcgga ttgtcgttgc caaacactgt gttccatttc cctttataat cagcaggatt 2925721 gctgatggca atatctgcgt tttcagccaa aaagtcatca gcccaaggct tgtggcgcat 2925781 tctcatatga ttgacacctc tatctattat ttcgactaac aacataccat gaattaaaaa 2925841 gacccgcaag ctcgtttttc cagtgtatct ctcttaaggc cgagcgcata aaaaaagagg 2925901 gtcccgtctg ctggaacact cctttcccat gtataaaaac gctctgtttt gaacaattta 2925961 acccgtatga tactgaaggg atgtgtaccg ttatgggttt acattatgag catcaagttc 2926021 atttattgaa ggatatattg actgaccatc aattggactg ctgcggaaca gtcgcagagt 2926081 acgagcagct tgagcgtgtg attaaatcac tgatggcaaa caccgagctt gattcaaatt 2926141 tcaaaaacgt gcttgaagat gtttaccgct acagccaatc aggaatatcg tccaaatcca 2926201 tcgactcaca catacaagag catcagaaca gcctgtctca atgggtagag caaatggatt 2926261 cgtattcctg attaatcaac aattcgtttc atgaggatat gcagctcttc cattgcatca 2926321 tgaaattcct tatcattgcc ttttgcttta tgccaggcaa tgaaagtaat tgtttcagat 2926381 aacacatacc aagccattcg caaccgaagg ctttctgtca gctctatgcc gtacatgctc 2926441 agccagctct cccaagctgg cttttcgacg tagtggtaca gcaaaggccc gaggtccatc 2926501 gccggatcag cgatcatggc gccgtcccag tcaattaaat acagctggtt gtcttcagac 2926561 aatagccagt tattatgatt gacatcacaa tggcaaacga ctttctcacc gaaatgcact 2926621 tcatgcaggt gttcttccaa atacttgatc ccttcttgaa tcagcggcga agattgctgc 2926681 acagcaaata cagcctgctt cagctgagac aaaagagccc ccgggttcag cggttctttt 2926741 ccaagtctct tcagcatgtc cagcaaggct tttgatgtgt gtattttacg aagcaattca 2926801 gcaacgggcc gtccgctcat gtctttaggc ttcagctctc tgccggtcat ccagtgctgg 2926861 gccgtaatga cgtccccatt ttccatccgt tttgtccaaa ccagcttcgg aacaatgcct 2926921 tcggcggata aaacagctaa aaaaggtgag ctattacgtt ttaaaaaaag ctgctgcccg 2926981 ttatgtttcg cataatatgc atctcctgta gctcctccgg cggggaagat ctcccaatcg 2927041 ctacctagta attgtcccaa ccagttcata tcaatgttca acccatcatt tcttaaaata 2927101 ttttagaatt aaggctaatc gtttctagtc tatccagcga atgccttttt cgtacgaatc 2927161 gtataaaaat aaaaaagaca gctattgaga gtctcatatg ctaatcaata gccgtccttt 2927221 aaattttagc gctatagcac aaacttcgtc aagcaaaact cttaagatct gatgctaaat 2927281 ataagataac cgttccgatg ccgtttactg caaccgtttt cttgatttct gttgggtctt 2927341 cctgaaatcc tgatggatca cataaaagcc gataaggtat gtcgtttggc agcctccact 2927401 cgacggagtc tggactcgcg tgatggataa caatgatatc tttccattcg tcaacctcgt 2927461 caagatcata aagcctgtat gcgataaggt gttcttttag cgtcaagcat tcaagatggc 2927521 gctggatgtc tgcagcggac ctaagacgga atgcaggatg cgcttttctc agcgagatca 2927581 gcctgcggat atagtgaaca tcttctttga atgtttcacg gcgatcccag tcgagctggt 2927641 tgatgctgtc actggattga tagctgtttt ccactccctg cttcgtccgg aaaaattcct 2927701 ggccgctgtg aataaacggc accccttggg caagcaaaat aatcgcggct gcaagccttt 2927761 gcctgcttcg ctttcggctg tcattttctt gaggaagcgc aaagctcatt ttatcccaaa 2927821 aggtgtgatt gtcgtgtgat tcgacataat tgatggactg gcttggttcc ggaacaatcg 2927881 gtgctaatgc cttccatccg gaagacccgg caattccatg catcacagct tgtgctgatt 2927941 caccgttgcc gagcgcaaac cctgttgcct taaggtgaaa ggtgttccct tttacagcgt 2928001 cacgaaacat atcattaaaa aagccgatgc ccggcattct tggcgcgttc gccaaagcag 2928061 ctttctgttc atgcggcagc ggtgtagcca ggtcccaccc ttctccaaaa agcaggattc 2928121 cgggctttgc cttagttgct ttctctttca tataaagcac ggtgtcaata tctaaaatcc 2928181 cgaggagatc aaagcggaag ccgtcaacat tgtattcttc aagccaatag accacgcaat 2928241 ccgcaatgaa ttttcttgcc atccttcttt ctgatgcaat atcattgcca acgccggtgc 2928301 cgtttgatgg catcccacat tcgtcgtgcc ggaaaaaata accgggcact gtcttttcaa 2928361 agggggaatt ctccctctta tacacatggt taaaaacaac atccagaatg actcgcagac 2928421 cgtgctgatg cagggtattg atcatttgtt tcagctctgt ttttctcgtt tgaggatcat 2928481 gaggatttga ggcatagctt ccctccgggg caaagaaatg aagcgggtta tatccccaat 2928541 tgtatgcatc aagcggcttc tcttcatcaa ctccggcaaa atcattcacc ggcagaagct 2928601 ccacatgtgt cacaccaagc tcttttacat acgctaatcc cgaagaactg ccatttgcgg 2928661 tttgtgtatc agtttccgtc agcgctaagt attttccctt gtttatcatg ccgctgtttt 2928721 catggatgga gaagtcgcga agatgcgtct catagatgac ggcatccaca gggtgtgaga 2928781 atggtttaag aggagcagtc catttcattt gatccgggcg caagacgacg cccttctctc 2928841 catttacagt cacagccttg gcatactggt caactgtttc catccattct gaattgttgc 2928901 agatgcaaaa caaatactca tatccgtgaa ggtcacctgt gaccgtaacg gcatagacgc 2928961 ctttttccaa gcgagtcatt tggaatgtgc gcccgctttt attggggtgt gaaagcttga 2929021 cagcagctga ggttgcagca ggcgcccata ctttaaatac ggtatgatcc gcggtataaa 2929081 cggcgcccag ctctccgtca taataaaatt cgtcatcaaa cgctgccgtc cggatgaccg 2929141 cgccaatttg gagatccgtt ttgtggccgc tggatgctct gacgcaatgg atttttccaa 2929201 atgtcacagg atggtcggat acgcagacgt acttgtattt tgcttcaagg gagtattcct 2929261 ccctgacagc cagaggaaaa tctgttattt ctgtctcaag ccgaaacggc ggtgtcatga 2929321 tttccttttg ttcagcagga atcagaacag taatgatatt catgtcatcg acatacgctt 2929381 cgaagctgcg gcggatgctg accatcggaa gctctctcct ccaaacacgt ttatgttttg 2929441 attcttaggg gtgaaggact agatgccaga cgaaacgggg tagtgcccat gatttctccg 2929501 tcagcatgga acgggatttt gtccttcgtg taaaatgtaa tgtccttcgc tttaaacatc 2929561 gtaacgccat ccatctttgt atgttttcca aatgccatga gacataaaag ccaatatttt 2929621 ttcaaaaacg gctggttttc aacgattacg atatcaaatg tcttctcgcg cggatttgct 2929681 aggggcgccg ccttcatgcc tcccccgtaa aacggatggt tggatacaac ggcaaaccag 2929741 acatcatgaa attcgcgcgt ctcgtcttcc gtcgtacaag ctaatgtaaa cggcttaaag 2929801 gttgccgaag cgtgcaaatg agaaagcgga tacacaagaa atcgaaggcg gagaaaaaga 2929861 aaaacccgtc tcaacggaaa ttccatcgcc tttttattga catatgcgtc aaacccgatc 2929921 ccgatatgat tcataaaata aagaatctgt gatttatcct gaaggaaatt gacgctccct 2929981 aaatgaaagg ttcttgttaa cgggcgcttt accttcttga tttcctgtat cagatcgatt 2930041 tttttaatag agaaccctcg cgaaaaatca ttatacgcgc ccgccggcac aaagctcagc 2930101 tcaatatcgt caacatcttt cagcccgttg acaacttcat gcatggttcc gtctccgcca 2930161 atgacgatca ggcgcttcag cttatattcc tgtatcgttg aaatctgtct ggcgagcacc 2930221 tcggcgtgtc ccggatgttc agttaaaaat gaacggtgct caacctttcg tttgatcaat 2930281 tctttttgaa tggacttcca aacacgcagg ccgtttcgat gtcctgctgt cggattaata 2930341 ataaaaaacc aatggctcat ctttctcacc tgcttatgtt atgagaaaac cgctcaaatc 2930401 gttctctttt actccagcca ctcctgtctg cgataggagt cagacatgca gtaagacaat 2930461 agagcctttg cagcctttac ctgatgatgt ttgatcggag cagtgttttt cttctgccgc 2930521 tcaatccatt cttccgcgct ccgcttatcc gctatttcta agccgtatgg cggctccggg 2930581 taatcgatgt acgacgttct gctcagaagc aattttcgaa ccggaatctc agcctgtttt 2930641 tcctttacga tctttgacac aaccgagtcc gtacgaaaca ggctaagccc tggatttaac 2930701 actgatgcag tctgagaggc tgttttcttg tcccaaaaac gatttttaga ccctatgtag 2930761 acactgtctt cctcagcctc taaaaaagaa acgcaataaa tttccagagg agaaataatc 2930821 acaatgctta attcaaccgc cgcctgctga attttcagca caggcttata cataataaaa 2930881 taagaatcag gcagctgctg ggtcagataa cgcaaaatgc ggtcctgctt cacttggttt 2930941 gagagttgag atatttctga aagagtagag cttgcccatt tgagctgaaa atcatataaa 2931001 tgccttttat aaaaagaagc aagcgccacc ctgctcttcg ggagccttac atgaatatct 2931061 tcttcgtcct caaaccattg gtgtctctct tcttgtatat cggcttttat ctcttctttt 2931121 cttcttttca atgaaaattt ttttcgtttc tgcaccggtt ccggttcttc agcactggct 2931181 tgcctttctt catgctggcg ctccgctgct tctactagtg aaagccagcg ctcttttttc 2931241 aaacgtacaa actggttgat ataatggtac ggatcaagct catatctcga tatataatca 2931301 tgaattttga tgatttgtgc catgtttgtt tctccactcc gcaatgaatt aagataattg 2931361 aaatttgaat atttcctcgt attttggtga ttggttcaag tgtatttgaa agagcgaaaa 2931421 tcgttcagcc atcatcgaaa cctcgccgct ttcaaacgga acatgagctg gaaatccatc 2931481 ttcgcctgtc cattttcttg ccagcgtcat atgaggatga tacggtcttt tttccacttg 2931541 aaagccggcc tgaagtacag cctgcttcgt atgttcccgc agtctatcaa gcgttttgtt 2931601 tttctttggc tccagatgta aaacgcgcgg ctttctgcgg tcgccgaata catctatctt 2931661 gccaaactta attgaaaatg gatcaatttc tgaagcaatc tctgctagcg aaccttcaag 2931721 cttctttatt tgtgtctcat ccgccgctcc gagaaaaatt aacgtgatat gatagtcaag 2931781 cgggtgcacc catttttgaa acgtcaatat cggttcgttt ttcgcagcct ggtagatcgg 2931841 atttgcaatt ccctcaggta tgggaacgcc gatgaaataa tgaggccgta tatctggcat 2931901 ccgtctgaca ctcccttctt tgacagctat tattttatca ataaagaggc tgtgcggata 2931961 gaggaacagt gtatgaaaac actctcgcac aaacgtttat tatgttagga tattatatga 2932021 cacttgtttt attcagaaag gaatgacaat gttgaaaatc gttgcaaaca cagctgatct 2932081 gataggagat acaccgctag tgagattgaa tcggcttcag ccggaaaatg cggcacaagt 2932141 ctatttaaag cttgaatttt tcaatccgag cggcagtgtg aaagacagag ccgcttatca 2932201 aatgatcata gaagctgaac aaaacggttt actcaagccg ggatcagtta ttatagagcc 2932261 gacaagcgga aataccggca tcgggctcgc catgaatgcg gcagcacgcg gatataaagc 2932321 aatcttagtt atgcctgata cgatgacgaa ggaacggatc aacctactta aagcttacgg 2932381 tgcagaggtt gtattaactc ccggagagga aagaatgccg ggcagcatca aaaaagcgaa 2932441 ggagcttgcc gaacaaattc cgaacagcta tattccaatg cagttcgata acactgctaa 2932501 tcctgatgcg caccgaaaaa caacagcgcc tgaaatcgcc cgggcaatag aggaaatcgg 2932561 aaaaccgctc ggcgcttttg tagcctcctc tggaacgggc ggaaccatta ccggaacagg 2932621 tgaggcgctc aaagagcttt ttccggatat cacggttcat gttgttgagc cagcgggttc 2932681 gcctgtatta tccggcggaa aacctggcgc gcataaactt gtaggaacga gcccaggctt 2932741 tataccgccg attttaaatg aagacgttta tgatgaaatt atcaaaatct ctgatgaaga 2932801 cgcgtatacg acgacaagac ggcttgctgc tgaagaagga attcttgtcg gtccttcatc 2932861 aggcgctgcc tgcttcgcgg caatcgaaac agcgaaacgc ctctctcctg acaaagttgt 2932921 ggtctgcatg acagctgata caggagaacg gtacttatca actgatttat ggtcatttat 2932981 ttaaaaaaag gactggcttc agcagaagcc ggtcctttta ttttgcaagc tcgtaaatgg 2933041 cctgagcata taacgctgtc gatctcagca ggtcatcaat ttcgatatat tcatcctttt 2933101 ggtgtgcgct gtcagggcgt ccggggaaca gcgggccgaa cgcgacaccg gcttttaagg 2933161 atctcgcata agtccccccg ccgattgaga ttaaatcagc ttttttaccc agctggcctt 2933221 cataaacctt ttgcagggtt ttgactaacg gatgatctgc ggacacgtga tgcggcttgc 2933281 tgtctttgaa ttctcccagc tcaaattcag atgcgctttc gaatgtatcg cggatcactt 2933341 tgctttctgc tgtcacagga tagcggatat tgatcccgag ctcgcctcct tgcccttctt 2933401 tatagcgcag tgttccgaca tttaatgtca gctctccgct gatttcatcc tcacagtcga 2933461 tgtccagttt ttttcctctt gtatcacctg agaacttatc tgtcacaact tgcacaaacc 2933521 gctttcctgc atcgtcaagc tcagtctgct ggagaaattc gcacaataaa atgccggcat 2933581 tgatcccatt gttcggttcc atcgcatggc aggaaagacc gtacatacgc aaaatgagct 2933641 gtccgttctc tattgcagct tccccttttt ggtccgtcgt gcggagcatg tctttaaatg 2933701 aagacagaat ctcttcattt ttcggccctt caatgacagc ttccgcagcg tcgggcacca 2933761 tgtttaagcg aaggcctgat tgaaacgaga caagcactgc ctttggttca gcttgatttg 2933821 ggcggtgcgg aataagtaaa gaagcatcga tgatcccttt ttccgcatta atgatcggaa 2933881 aatcggcgtc aggcgcaaag cccattgttg gcatttcttc atgcttgaaa taatgctcta 2933941 cgcatctcca atcactttct tcatctgttc cgataatcat tctgactcgc ttggacaggg 2934001 gcaaattcat gtctttcacg attttcagcg cgtagaatgc cgccattgtc gggcctttgt 2934061 catcaatggc gccccttgca taaatccgtc cgttgcggat ttcagctgaa aatggatcac 2934121 tcgtccaccc atctcccggc ggcacgacgt caacatggca aagtacgccg ataatgtcat 2934181 cgccctcccc ccattcaata tgacctgcga agccgtcaag attttttgtt gtaaagcctt 2934241 ctttttctcc aagctccagc aatgaagtca ggctggcatt taccccttct ccaaacggtt 2934301 taccgggtcc ggcggttgtt tcgtccatga cactgttgat tctcaaaaat tcctgtgtat 2934361 cacgaattaa atcctctttt tttctgatca cttcaacttc ccagttcata atgatcccct 2934421 ttccgcaaga aatgacttgc aaaaaccaaa taaaacgaat aatattaatg gtgttttgtt 2934481 aaaacgttcg taattggagg atactatgtt tcatctaaaa gagcagcaaa catccataaa 2934541 gcaagaaatc atagcagggc tgacgacctt tttcacaatg gtctatatcg tcgtggtcaa 2934601 tccggtcatt ctggctaacg ccggggttcc tttcgaccag gttttcaccg caacgattat 2934661 tgcctccatt gtcggaacgc tgtggatggc cctggcagca aattatccga ttgctattgc 2934721 gcccggcatg ggcttgaacg cttatttagc ctttcatgtc gtaagcgcaa gcgatggcgg 2934781 catcacgtac gcaacagctt tcagcgcagt atttacagca ggggttctct tcattattct 2934841 atcgttaacg cctttaagaa aacaacttat agaagcgatt ccaaacaatt taaaatacgg 2934901 gatcacaaca gggatcgggc tgtttattgc ttttatcggt ttgcgtcaag cgggaattgt 2934961 ggcagctgat gagtcaaacc tggtcactct cggcaatctg cattcacctg gtgttatctt 2935021 aacgctggtc ggccttttga tcagcgtggt cctgatggtg ctgaatgtaa gcggcgcttt 2935081 atttatcgga atggcagcta ccgctttgat cgcctttttc accggtcagc tccatttttc 2935141 aaagggattt atgtcgcttc ctcatttgcc ggaaggattg atgatctcaa atccatttac 2935201 cgcttttggc gatgtcattc atcacggcct gtacgctgtc gtcttttctt ttctattagt 2935261 caccattttt gatacgacag gcacgatgat cggagttgcc gagcaagccg ggctgatgaa 2935321 aaacaacaag ctgccgaacg tgcgaaaagc gctgcttgct gattcaaccg cgacgacagt 2935381 aggagctgtt ttcggcacaa gtccgacgac tgcatttatc gagtcttccg ccggtgtcgc 2935441 agccggggga agaacggggc ttacggcttt gactgtcgcg gtgatgtttg cggcttcaat 2935501 gtttttcagt ccgcttgtca gcgccttgtc aggtatagcc gccatcacct cgcctgcttt 2935561 gattatcgtc ggcagcctga tgatgggctc agtttccaat atgaactgga aagagatgga 2935621 cgaggcattt cctgcgtttc tcgtcattct agccatgcct ttgacctcga gcatttctac 2935681 aggaatcgcg cttggcttta tttcgtaccc aattgtaaaa gcggcgcggg gaaaatggag 2935741 agagattcat ccgctcgtca tcgttttcgc cattctgttt ttcatccagc tgtttatttt 2935801 ataaggatag accaaaaaac ccaaacgtcg ccgtttgggt tttttatgta aacaataaag 2935861 agacagcggc cgctaaaaaa caacaggcgg caaacgcata gtgcaggatg ttgatacagc 2935921 tttttctggc ccgataatat tcatcacttt ccttatcggt gccaattaaa aaaggggcat 2935981 ccatgacctt gtcaaaaata agcgtcagga tataacggca aacccctgtg tataccagca 2936041 gcgcaatcac cttcagccaa attggggaaa caaatatgag aacagtgaaa gctgacagta 2936101 gcatgtacat ctgccttgca tactcgccat tcctcagcat aactttaaaa aacaactcct 2936161 tatagcctgt gcagatcgtt cgtcttttaa atatcctttt tgaatttcgg tataataatg 2936221 gttttcttct catcctgtct tttacttttg gcattcccgc ctcctgactc atcatcatca 2936281 caagtcctgc aagggcaagc ctgctttttt tctcttcagt cacctcagct tcaaaagccg 2936341 tgaacgaggc tgtctttttc aaactgcgga taactgagaa aaacaaaaat aaaatgccaa 2936401 aaagcgcaag caagtgccgc tcagtaaaaa caatcaggat agcagaacca gcaaaaagaa 2936461 tagctctgac aagggtatcg ccaatccatc tcgaaatgga gcgcggcttt ctgatcctgt 2936521 cttgctttaa ggataaaaag aatatatgaa ggccaaacaa ataacacaat agagcagtgc 2936581 tttctgcgaa tgtgatgaga acagaatgac tgatcaaggg aaggacaatg aaaaagagaa 2936641 gcagccattt agccagcgtg gccagaaaag aatacaaaag cgcataccgt ttgagctgat 2936701 agatgatttc cttcttttgc agcaaaaaca ctttgtccgc ttccattaaa aatgtacgaa 2936761 tcgaacctgt aaacatgatc agcacacaca cagcatacag ccatctccat tccgccactt 2936821 cagaccactc ataaagaagg cctcttccgt tcatcaaatc aatatactga tagatgacaa 2936881 aagcaatcgc cggcaaaacg atatagagag cgactgtcca gtcaatgacc gcatgcaaca 2936941 ctttaaactg atacttataa tagtcaaaca gccttcgaaa aaagagcgta cgcccgttca 2937001 tagccgatca ccttgaactg ccttataaaa acagtcaagc aatgactgcc cctctaatcc 2937061 ggtcttgtcc tgaacatctt ttaacgtgcc ttggagaaat aatgaacctt tctcaatcat 2937121 ataaaaccgg tcacagattt tttccgcggt atcgagtaca tgcgtgcaca taagaattcc 2937181 ggctccacgt tctttttcag ccttaagcat gtccacaaag cgtttcgtcg atatcggatc 2937241 aaggccgata aacggttcat caatcacata catatccggc ttagagagaa aggcctggat 2937301 aagcattagt ttttgctgca tgcccttcga aaaggtgaca ggcagctcat gtttgacatg 2937361 atctagcgaa aacgtctgca gcaggctttg ggcccgatgc gcaaattcac tctcttcaat 2937421 gccgtgaagt gtgctgatca gatccaaatg ctcccacagc gtcagttctt cgtagaagga 2937481 cggatgctcc ggaatatatg caaatgaaca gtcgttccag gcaatatgcc ctttaaaatc 2937541 ttctgaaagg ccgagtatcg ccttgattgc ggtgcttttt cctgcgccgt tagctccgat 2937601 cagtccaacc agttcccctt ttctgacttc cagaaaaaca tcggtgagca ctttttttcg 2937661 gcttgtatac ccggcctgtt ctattgaagc ttcaagcaaa tttgtcaaaa ctcactcacc 2937721 tccaaaattt actacgaaat agaataaaaa aagtttcttt aaccataata atattgagcc 2937781 gaaatacata gtaatccaac aaggatggct gcccaacgcg aaattggaaa aaattaatag 2937841 gagttatccc tagattcatc actgcaatat cgtgtataat gagggcgaat tattttaaca 2937901 attacagatg tctgcctttg ttgctatttc gtacgcagtt gatagtcgtg agttgtggtt 2937961 agtcaagtcc atccgatctt atgataggga gtggtttttt gaaaccttca acaaaccgta 2938021 tgctaactcg aatcaaatca gtttacatgt ttattcaaga aaaaggtctt gtgacaacac 2938081 aggaactggt tgacgaattc ggcattacac ctagaacgat tcaaagagac ttaaatgtgt 2938141 tggcatataa tgatcttgtt catagtccaa gccgtggcaa gtgggagaca acgagaaaga 2938201 aagtaaagat tacctcataa attgaaaatt acatagggcc gcctgagagc ggtccgatag 2938261 ataacagggc gaagaaacta ctgagccttg tttttgtgtg cttataaata aaaccccgca 2938321 ttcggtatgc ggggtttttg tcatgcttgc ggctcattta gcaaatgaag ctcttcctct 2938381 gtcagctcac ggtattctcc gggtgccaga gcgggatcta gggaaacgcg tcccatcgaa 2938441 agccgcttca gataaaccac ttcattgccg actgcctttg ccatttgctt gacctgatgg 2938501 tattttcctt ctgtaattgt cagatatata acggtattgc cactgtcgtt tgttttgatt 2938561 tccgcttttg ccggctttgt tttatagccg ccctctatgt agacacccgt ttccaaatcg 2938621 gaaatgtctt cccgagaaat ctgtgatttt aaatggactt catacgtttt tggaacatgc 2938681 tttttaggag aaaggagccg atgtgcgagc tggccgtcat ttgtgagcag caaaaagccc 2938741 tctgtatctt tatcaagcct gccggctgga aatggctcaa atctcatctc ctccggcgtc 2938801 agcagatcga ccactgtttg ctgccggctg tcctcagtcg ccgacagcac gccctgcggt 2938861 ttattcatca taagataaat gaactctcga taatcaaccg gttccccgta tacggtcacc 2938921 tcctgcgtat caggatcaac gtgctccttt acatctttgg caggtttgcc gtcgatcatc 2938981 acggctccag ccttcacaac ggctttgact tcttttctgg aaccataccc gctgttggca 2939041 agcagcttat caagtctcat tcccaatctc tcctttataa aagaaagccc gcagcatgcg 2939101 agccctcagt ttcatcatat ctagttcatc agcctgcatg tctgcctttc ctaaagaaac 2939161 ctggcaaacg gcggcctaaa attttctgca aaaatcctaa tcggtagccg caatacaggt 2939221 agacagctcc gccaacagcg gccgcgatca ccacaacaat cgcagcttgc atctggccat 2939281 cctgatagga aataaagaag cctaataccc actgcacgat tttcacggca atacccataa 2939341 tggctgataa gaccagcatc aaaacagttc gtttaacaag tatcttatac gaatagcctg 2939401 catggcgctt aatcatgata aacccatata aaagggaagc gatatatcca agcgccgtcg 2939461 ctaaaatcgc tccgtcagcc tgcatcagct tgatcagcgg aacattcagc acaagcttga 2939521 tcacgacacc gatcacaagg ctgacaaccg caaatttttg cttattgatg ccctgcagaa 2939581 tagctgcgtt gactgtaaac aaagagaaca gaattgcgac aggcgaatac caaagcaaaa 2939641 tgtttgcccc cagttcagga tgaaggctct ctgacccgta aaagaacgta tacgtcggtc 2939701 ctgacaatag agagatcccg acaacagccg gaataattaa aaacaggatc gtctgcatcg 2939761 tttgattaat ctgctgattt aacagcttat agtttccgct tgtaaacgat tcagtaatcg 2939821 ttggaattaa tgtcagtcca aaagcagttg ctagggaaac cgggatcatc acgagcttct 2939881 gaacatacag ggttagaatc gcaagcatgt cctggctgat ggcttgatga ccggcttcaa 2939941 tcatcgcttt gttaaacgta tttgtatcaa tatagttata caaagggatg gctagtccga 2940001 caaaaacgta cggagcagca tagctgaaca gctcgaaaaa cattttcttg tagcttaggt 2940061 ttgctgtcgg acccgtattc ggcatcatcg ccagcaggct gcccttccgt ttgttccaat 2940121 aaatataaag cacgaccagc cctccgaagg caccgatcag cgctgcgaag gttgcatagc 2940181 ccacagcgat gacaaggccg ccgttgaaaa ccttcaaaat caagaatgtc gcactcaata 2940241 gaaagatgat gcggacaatc tgttcaacga cttgggaaac agctgtcgga cccatcattt 2940301 ggtgcccttg aaagaatccg cggacaaggc tcataatcgg tacgaccaaa agcgctaagc 2940361 tgaccatgcg gatgacataa acgacatgat caattgtcag gccgttatta tccttgcctc 2940421 ccagcgatat ttccgcaaac atcggagccg atagatacag aatgaaaaag gctatcattc 2940481 ctgtgactag cataaccgac atgcccgcct tgagcatttt cctgcttgtc tcataatccc 2940541 cttttgaatt atatttggaa acaaatttag aaacagcggc cggaaagccc atcgtagcaa 2940601 tattcaaaaa taaagtgtat tggttgtatc cgtattgaaa taatgcaccg cctgtcgccc 2940661 cgaccataat gctgaaggga attaaataga ccatccccag aatccgcgat atatatgtac 2940721 cgagcgttaa tacaaacgtg cctcttaaca gtttgcttga catgtttctt catcaccatt 2940781 ttctacgaag attcaacttt tctattttac cacaactggg catttagacg gtaataaata 2940841 caaaagcaat cctgtgaaca ttcatgtccg cggcaaaaga cgtttaagga gcggctttct 2940901 ttcgctataa tagtactgcg gacgggtgtc cgcacacgaa atgaaaagaa agttgatgat 2940961 aaagatgaaa caatatgacg taatcgtaat cggcggaggc ccttcaggct tgatggctgc 2941021 gattgcagca ggagaacagg gcgctggcgt gttgctgata gataaaggaa ataaattagg 2941081 acggaaactc gcgatttccg ggggcggccg ctgcaatgtg acgaaccgcc ttcctgtgga 2941141 agaaattatc aagcacatcc ccggcaacgg gcgtttttta tacagcgcgt tttctgaatt 2941201 taataatgag gacattatca agttttttga aaacctcggc attcaattga aggaagagga 2941261 tcacggccgg atgtttcctg tgaccgacaa agcccaaagt gtcgttgacg cgctgttaaa 2941321 caggctaaag cagctccgcg taacaatcag aacgaacgag aaaattaaat ctgttttata 2941381 tgaagatgga caggcagcag ggattgtgac gaataatggc gaaatgatcc atagccaggc 2941441 agtcattatt gctgtcggcg gtaaaagcgt gcctcatacc ggaagcacgg gagacggcta 2941501 tgaatgggct gaagccgcgg gccataccat aacagagctg tttccgacag aggttcccgt 2941561 cacttctggc gaaccgttca ttaagcaaaa aacacttcag ggcttatcac taagagatgt 2941621 agccgtcagt gtgttaaata aaaaaggcaa accgattatc acacataaaa tggacatgct 2941681 gtttacccat ttcggcctct caggacctgc cattctcaga tgcagccaat ttgtcgtaaa 2941741 agagctgaaa aaacagcctc aagtgccgat cagaatcgac ttgtatccgg atatcaatga 2941801 agaaacgctt ttccaaaaga tgtataaaga actgaaggaa gcaccgaaaa aaaccattaa 2941861 aaacgtgctg aagccttgga tgcaggagcg ctatctccta ttcctgctcg aaaaaaacgg 2941921 catctctccg aacgtatcgt tttctgagct gccgaaggat cctttcagac aatttgtaag 2941981 ggactgcaag cagtttactg tcctcgcaaa tggcacactg tcgcttgata aggcatttgt 2942041 cacgggaggc ggggtatctg taaaagaaat tgacccgaaa aagatggctt ctaaaaaaat 2942101 ggaggggctt tatttttgcg gtgaaattct ggatatccac ggctacacag gcggatacaa 2942161 tattacctcc gcccttgtca caggcaggct tgcagggcta aatgccgggc aatacgcccg 2942221 ttcttaatca ttactcttta aatctcttgc cgccaaactc acatttgaac attccccgca 2942281 ttcatgttag ggtgagactt gttttgtttc acctgattgc ggggtaattt taagagagga 2942341 atgagctgcc atcgtacgac catactaagc ctgcgagcaa gatataggcg tacacaaaaa 2942401 attagagggt gagaaatgtt gaaacatata tctagtgtat tttggattgt gattgcaatc 2942461 acagctgcag ctgtattatg gggtgttatt tctcctgaca gcctgcaaaa tgtgtctcaa 2942521 tcggcacaag catttattac cgattcattt ggttggtatt atcttttagt tgtctctttg 2942581 tttgtcgggt tttgtctctt tttgattttc agcccgatcg gaaaaatcaa actcggaaag 2942641 cctgatgaaa aaccggaatt cgggttatta tcatggtttg ccatgctgtt cagcgcaggc 2942701 atgggaatcg gcttagtatt ctacggtgcg gctgaaccga tcagccatta cgcaattagc 2942761 tctccatcag gtgaaacaga aaccccccaa gccttcagag atgcactccg ctatacgttt 2942821 ttccactggg gtttgcacgc ttgggccatt tatgccattg tggcattatg cattgcctat 2942881 ttccaattcc gcaaaggcgc acccgggtta atcagcagca cactgtcacc gattctcggg 2942941 gataaagtaa acggaccgat cggaaaggcc attgactgta ttgcagtttt cgccactgtt 2943001 gtcggggtgt caacaagtct tggtcttggc gcaacccaaa ttaacggcgg tttgaattac 2943061 ctgttcggca ttccgaatgc gtttatcgtc caattggttt taatcattat tgtgacagtg 2943121 ctctttttac tttctgcgtg gagcggactc ggaaaaggaa ttaagtattt aagcaacaca 2943181 aacatggtat tggccggatt gttaatgttg tttatgctcg ttgtcgggcc tacagtgctg 2943241 ataatgaact catttacaga ttctatcgga caatacattc aaaatatcgt tcaaatgagc 2943301 ttcagactga caccgaacga tcctgaaaaa cgcgaatgga ttaacagctg gacgattttc 2943361 tattgggcat ggtggatttc ctggtctcca tttgtcggca ttttcatcgc ccgtgtatcc 2943421 agaggccgga cgatccgcga atttttaatc ggcgtcttgg tgacaccttg tattttgaca 2943481 tttctatggt tctccatttt cggcgtatca gccatggatc tccagcaaaa aggcgcgttc 2943541 aatgtagcaa agctgtccac tgaaacgatg ctgttcggaa cacttgatca ctatccgctg 2943601 acaatggtga catcgatcct tgcattgatt ctgatcgcag tattctttat cacgtcagct 2943661 gattcagcta cattcgtgct gggcatgcag acgtcgtacg gttctttaaa tccggcgaat 2943721 tctgtgaaac tcagctgggg tatcattcag tccgccatgg cggctgtgct cctatattcc 2943781 ggagggcttg ccgctttgca gaacacagcg attctggcag cgctgccgtt ttctatcgtt 2943841 atcctgctga tgattgcctc tctctatcaa tcgctctcaa aagaaagaag agagatcaaa 2943901 aaagcggaga aactcgataa accaagaagt ccaagagtga aaaaagcata ttaacaaaaa 2943961 agatctttcc gcgcctgcgg aaagatcttt ttatttgcga tataaaataa gggcggaaaa 2944021 acagtaaagc tgctcgccgt ctgggtcgca cgccgccgaa accgtatatt tgatatctat 2944081 cagctgctcc tccgatatcc cttttaaaaa tgaattgatt tccgtttgta agtctttttc 2944141 atgctcttca tcaaataccg ctaccttcag cattttatcc gctctccttt ctctatcaat 2944201 ctattccgtt tggaacagcg ttatgataga gaaatgatga ttatctcgtt tccggataaa 2944261 aagctttccg tatatgggat ttcctctgtg gctcgccgcc gtgctgctcc actttcagca 2944321 gcacggcata aacaatgcgc atatggcagt agctgataag gctgacgctg aaaaaaggga 2944381 caatgcccgg caggtacgca agcaagaaaa agagagcaac agtcagcgca agcatagtaa 2944441 gcgtatattg caaatacgcc acactgagca agagcgaaaa tttcacatac agacgttttt 2944501 tccagtcaaa atggacaagc agcggaaaca cataaaaaag catggatacg aacaaaaagc 2944561 caaatatcat aatggcgaag cgcaggatgt gcagaaggaa atgacttgga taaattaagg 2944621 ccaaatcaat ataaatgatc actccgatga gcgccagtac agcgccgagc agatttgaac 2944681 gaaaaaattc acccttgtat tcctgccaaa acgttttgag caccggaacg ttgtcctgcc 2944741 cctggatcca cttccgcatg acagcgaata aagccgcggt cgcgggcatg atgccaaaca 2944801 cgccgagacc gagcaacgta aaaaacagcc acagcaagtt tgtatacgca aatctcataa 2944861 tccattcgca aaaacgcagc atccgtccca gtgagccatc atgttccatg gcgccccctc 2944921 cttttttgca ttatacattc tgcatctgaa aaagctcttt catgccgatc ggcttctttt 2944981 cggcaaccga gcgccacatt ccctcaccaa ccgcgatgga gtaggctcca gcttcagccc 2945041 cggctaaaat atcatagcgg cgcagcgggt ctttccctaa aaaaagatcc tcaagcaaaa 2945101 gcggatcacc tccgccatgc cccccttcat ttttgaccac ttgtatcgtc tgctttgatt 2945161 caaaaagcgg atagtattcg attgtctgct caggaaaagc aaacggaatt ctggaaggtt 2945221 cgtgaaattc atttgattca atacgtcctt ttgtgccgtt gatcgtcagc cggtagcctt 2945281 catacggggc cgaaaaaata atcgagtagc ttaacagtgc gccgccatca tatttgactg 2945341 ccgccacgta cgtatcctcg atgtcaattt cctcgtcaaa aatacacgcg tcaggcctgt 2945401 atgcagtata taagctggac tggtctcctg cttcaagatg atcatccttt atagaagctt 2945461 tagaggaacg gggatgccac cttgaatagt agtggcattt ttctttaaca cggcacgtcc 2945521 cgcaaaaacg cccgtcttct tccggcaagg ggttccactc actgtccggc ccatagtaat 2945581 tcaaggcgcc ataagcaaat acctcttccg gattttgccc gagccaccaa ttgacgagat 2945641 cgaagtgatg tgttgattta tggacagaaa gaccgccgga aaactgtctc gacctgttcc 2945701 agcgtttaaa atagctggcg ccatgatacg tatcaatata ccaatttaaa tcaacagaag 2945761 tgaccctgcc tatttttccg tccagaatca tttcttttat tttccgatga aacgggctgt 2945821 agcgatagtt aaacgcgacg gtgacttttc cttcgctttt ggcctccgct tcaagcaccc 2945881 gattcgcatc ctgcactgtt gtcaccattg gtttttcagt aatcacatct gtattccact 2945941 gaaggctttt tacaatatat gcgacatgcg tatcgtccct gcctgccaca atgacgatat 2946001 caggctttga gacgcgcatc atctcgtcaa aagcatcttc gctaaactca ggcacgtggg 2946061 ccagctcggg aaatttcttc ttgcaaacgg caaaacgttt cggatcggca tccagcaatc 2946121 ccgtaatctc ataatgagtt gaaaaccgct ccatcagtgg tttgataaac atactgaatg 2946181 ctctgctgct caatccgcaa aagacgatgt tcttcaatat cctcacctct atcgggcttc 2946241 agttagttga gaaatcagct gcagcgcttc ctctgttttt tcagcataca cagggataaa 2946301 cgccgccata tcgcgattca attgaaaaga atagccgttc agctgttttt tccctttttc 2946361 gatctgaacg gcatagatcg ttttttctcc tgttttttta ttaacagttg tataaggaga 2946421 tgttttttca ggaggcaatc cgtttaacgg ctgaaaattt tccggatcat cgtaagcttg 2946481 aaacatgtct tcaggcacga tgaaaacatc tccctcatgg gcggtaattt cagtcagcag 2946541 tttttcctga aaagctggaa agatatcgac cttcccggca ttctgctcgg cggccttttt 2946601 tattttttcc tgtacgccag cctgcatatc agaaaagaga atgacatgca ttccgtccgg 2946661 cctgcttgag catgatgcca aaaagagcac tgagacgatc acacacaaag ccgtacgtat 2946721 cctttttgtc atttccccgc tgacctaaaa agaggctcca gctctgtcat agctaaaata 2946781 aacgcgccgg ctccgtgcag atcgtttgtg cttctttcgc ggctgacata atagtcatag 2946841 aaaccggctg acgttccgac acatatgtct ttgacgagaa acgctccgtc ttctgatgtt 2946901 tcggttttat gctgaatcaa gccttgatac gcttttagca gtgttgtttc gtaagctctg 2946961 tctagatagc ctttattgat tccttttgcg attgcgtaca tgtacagaca ggatcctgag 2947021 ctttccagcc agttatcaga cctgtctccc ttatcaacga tctggtacca taaccccgtc 2947081 tctttgtctt gatagcgaca gatgctttta atcatgtcct gcagcgtgtt tttccacaca 2947141 tgacggttcg gatgcttctt cggcagctct tcaatcatgt cagcaagaga catgacgtac 2947201 cagccgatgg aacgtgccca aaattccggt gaacagcctg tctcttcatt ggcccaaggc 2947261 atttttttcg cttcatccca ggcgtgataa aaaagtccgg tttttgcatc cttcgtatgc 2947321 tttctcatca atgactcctg aagcacaacc tgatcaaaca gctccgtctc ctgcttcaga 2947381 ttggcatatt tcagtgcaaa cggccccccc atgtataagc cgtcaagcca catttggtaa 2947441 ggataaccgt ctttgtgcca aaaaccgccc tcagacgtcc ggttcagtgt tccatataag 2947501 ctgcgcagcc tttttgccgc tttgacatac cgttcatcct tcgtctgctc gtataatgga 2947561 aaaagaatga gacctgcttg aatggcgtcc agttcatctc ttctaaataa tagattgcca 2947621 ttatcatcga ttaagagatc tgcataagcc ttcgcatact caaaataccg cttttccccg 2947681 gttgcttccc acagccgcaa tacaccgcat aagaaaacac cctgatggta gtgccagcgg 2947741 tttgcaggtg gcagctcctc gactgtgtac gtgttcataa tggtgtttgc caatgcctcc 2947801 gcgtacgtaa gaggcgattt tacagcgatt gattgatcca ttgatcccat ccctttccta 2947861 ataaattcct tcctcgccaa atttcttcgc caaacgattc gctagcatga ccaaaatcag 2947921 cccgaccgcc gctttaaata cgccgactgc tgtactgtag ctgaattggc cctgtttcag 2947981 ccctgcagta taaacatacg tatcaaaaat ttccgccact tccctgttag tcgcatttaa 2948041 cagcaaatac acatgctcga agccaagctc cagcgtgtct ccgattttca aaatcagcaa 2948101 aacgacgata acgcttttaa tggcgggcag cgtaatatgc cacatttgcc gcagccgtcc 2948161 cgctccgtcc attttcgccg cttcatacag ctgggggtca accgctgtaa tggccgccag 2948221 ataaatgatc gtcgaccagc ccgcttccct ccagataacc tgcagaatat acaggggccg 2948281 gaaccattct tcgttcagca gaaaattgat tttttcaccg ccaaaaaaca caatcagttc 2948341 attaatcaag cctccgtcta ccgttaaaag cacaaacgaa agcgatacaa caatgaccca 2948401 agacataaaa tgcgggatat aaatcagcgt ctgaacaaat tttttaaaga gagcaatccg 2948461 cacttcgttc aatagaagcg ccagcagtat cggcaccggg aaaaatatgg ccaggttcaa 2948521 agcaaataac acgagcgtgt tttttaacaa gagaaaaaat gtaggctcag taaacagcct 2948581 gataaaatgc ttcagcccca cccactcact gcccaaaatg ccgaggaacg gctgataatc 2948641 ctgaaacgca atcacaattc cccacatcgg gacatactta aaaagcaaaa aataaataca 2948701 ccccggcaaa atcatcaagt acaaatattt ttgttgaatc agcttgatta gtaagcgctt 2948761 tcttttttct tttttaaaaa tgactgcatc aacagccggc gcttgcgctt ctgctgtttt 2948821 cattttttcc tagcctcctt tcacggattc ttgcattcac tgtagcgcag caggcaaaag 2948881 tccgtctaca atcatatgat cacatcctgt tttatccctt tataatcaag ggttcagccg 2948941 gtccacctga aaaaaagaca ccgatattag aaaatgatta ttgacaatat ctatcaatct 2949001 ttggattaat tgtattaagg tgaagtggat gttatgaaat ggggggtttt atgaaaagaa 2949061 gccaatacaa gttttactac aaactgatca cgtttttctg cctgctcagc accattccgg 2949121 ttattttggt cggattattt tcgtacgagc actctcagaa aacggctatt tccaacgttt 2949181 cggaggaaaa attcgacaca ctccagcaga cccagcaaag catcgagcat atattgaaaa 2949241 ccgtcgatca ctctttaacc cactatgtga gttcgccgcc tctccttcgc acattgtccg 2949301 agcctttgca ctcagaccaa tttcaaatct ataaccaagt gaaccaagag ctcaattatc 2949361 tgcaaagctt tgataccgat ctgtccaaca tgacgttagt cagttatacg aaaaaatggt 2949421 acatgaacaa ttccggtttg taccgtttga atacagacac tcttcatgaa gcagcctcag 2949481 cgtacacgaa acaaaaagcg agccgctcct attggacgct tgaggaaaac aatcatttga 2949541 tttcaaccaa agaaggcaca gcagaaaact gccgctacaa tatcaattta attaagcagc 2949601 ttcctttgaa cagcacaaat acaaagggat tggccgccgc aagcatcccg agctgttcgc 2949661 ttgtcaaaaa tatgcccggc tattcaaacg ccaacaacct gtttatcatc gatgaaaaag 2949721 gcctcatcat ccttcataac aatatgtctg acgttggtga atctcttcat aacgacggct 2949781 ttgtccaaaa agtgctggcg caaacggcca atagcggaca gtttgaaaca gtgattgacc 2949841 ggattcatta taaagtcacc tatcaaaaat ctgactataa tgcatggact tatttttctc 2949901 tcgtttccct gcctgagtta aaaaaagaag ccaaatcaat cggctggatc acttttgcag 2949961 tatgcctcat tttgttaacg ctttcattgc tgttctcttg gcttggctcc cgccattttt 2950021 acaagccgat cagggtgctt tacgaatcat tcgcaagaca tggagccata caagagaaac 2950081 aacagcctcc tcaaaatgaa tttgagttaa ttgaacagag ctttaagcag ctgaaggaca 2950141 gaaatgacga ccttgaagaa acgatgaagc agcaggccac tcatctgcag caatatttta 2950201 tggtcaggct tatgcttgga aaactgacgg atgaggaggt tgataaccgt tttgaaagcc 2950261 tcggcttaaa gcaaaattgg cggcaccttg ccctgcttgt gctccaaatt gacacactga 2950321 atcatacgcc ttatgagaaa aaagatatgg atctgctttt gtttgccgtc aacagcctga 2950381 ttgagcgcaa catcccgacg gacaaacatc ttgcccccgc cgtagttgac aaacagcagg 2950441 cgacgatttt gatcaatcaa agcgggacaa aggaagaatt catggctgag ctgaatgaga 2950501 ctgcaaggat gattcaggaa aaagcggaag ctgagctgca gctgtctgtc agcatcggca 2950561 tcagccagcc gtttgatgtg ctgacaaaag cgaaaacagc ctatgcggaa ggctcagaag 2950621 cgttgaaata tcggctgaaa gcggaaaaca agtcgatcat cttttacgaa gaccttgacc 2950681 agaaaaaaac cttcaaaacc cattttccaa agcagcttca gcatgagctg ttcgatgctg 2950741 tcaaagcagg agacaaggag aaagcggata aatgcctgca cgcgatttta caagccattt 2950801 tcacccagaa caccaacccg tatcaatttc aaatcgccat cgcccgtttt ttgaaccatg 2950861 tgattgagct gatgcatgtg cttgggatcg aattgtttga gcttgaagaa aacaaaatgc 2950921 tgtatgacca aatttttgag ctgaaaacgt tcgaggatac cgaaaactgg ctaaagaatg 2950981 agtttattga tccgatgaca gacaaagtga acgcccgcgc ggatgcccag tacaaaaata 2951041 tttccgacaa catcattcat atcatccatc atgagtttga atccgaattg acactggacg 2951101 aaatcgcacg caggctgcat tacaacccaa attatttaag cagtattttc aaaaaagaaa 2951161 tgggaatttc attcagcgag tatgtctcaa gctaccgaca ccatatggcg aaaagctggc 2951221 ttgccgaaac cgacatggcg gtcaaggaca ttgccgaaaa gctgaaatat aaaaactccc 2951281 aaaacttcat cagatcattt aagaagctgg aagggattac accgggaaac taccgccagc 2951341 aaaaaagaag catgtaaaaa acccaaaacc gcttgcgcgt tttgggtttt tccaatgtta 2951401 ttttgcttgt ttaaacgctt cttcgtattc ctgaataatt tgttttcctc cgcttgactc 2951461 ccatttttcc acttctttat cgaactggct ttctgtgatg tctccaatca tatatttgta 2951521 ggtcgcgtca tcaatgattt tcttcagttc gtcaccccgt tccgactccg atgcggaata 2951581 caggctttca gccgggtttg agacgataat cttttcattg tcctcggtca gctcctcgta 2951641 cgccgtccga agcggatctc cagtgttttt taagtaggct ttatcaatgg caattaaagc 2951701 ggacagcggc tgaatatcag tctgccagtc ttttacctgg ctttctttgc gtgtaaacgt 2951761 tttgtcctca cctttgttgt aatgaacgcc gtcaatgcca taagtcatca ggctatagac 2951821 atcttcttcg gcaattcggt caaaaaacgc caagatccgt ttaagctcag cttccgtttt 2951881 cacactcgtt ttcgggaaag caaacacgcc gttatggcct cctgatgccc atacccgctc 2951941 tttcccatct gggcctttta tgcggttgat gatctcgagc ttcatcgatt tatcagaggc 2952001 atggtcgcgc agattgaccg catctaccat attgccaata taaattccgg cttttccttg 2952061 agaaaacagc tcttgctgct gggttttgct tgtgacggga aaatccttat tcatataccc 2952121 gttatcacgc agctttttca tatagttcat cgtgtctttg tattcctgtg tcatgaaatc 2952181 aggcgtgaat ttgccgcccg attccttcca atctgtcggc atgccttcat acgagccaat 2952241 cgttttaaac gcgccgtaaa tcaagtcatt acggtctgcc agcccgaatg tatcatcttt 2952301 cccatccttg tccgggtcgt cctccgtaaa tgctttggcc acttcataaa gctcatccaa 2952361 cgttttcggg gttttcaaat ttaaattgtc cagccagtcc ttccgaatga cgatcccctg 2952421 tctggaaagc gggcgctctc tgtatatccc gtagagcttg ccgtcaattg tcacattttt 2952481 attaatgagt ttgttcattt tgtttaagtt gggataatcc ttgatataat cgccgatttc 2952541 ccaaaacatt cctgaccgaa aggcattcat gactgacgaa tttttaatat cctggatggt 2952601 cacgatttgc ggaagattgc cggctgcaag cgctgcattc agcctgtctt ctttcaccgc 2952661 gtctggaacc caggtgatgt cgagttctgt atttgtcagc ttttcaattt ctttaatcgc 2952721 cctgtctttc ggcggctgct ggtgatacaa aatcgccatc caagacagct ttacctttga 2952781 atctgggcca gctttgcctt cagccgaaga ctgatcagtt cctttacagc ccgccagcac 2952841 tccgccgagt gccagtacaa gcacaatcaa aagcaccctc catttgtttc ccatcgtacc 2952901 cctccgtttc atatttcttt atcctttgac agatcccagc aaagctcctt ttgcaaaatg 2952961 cttttgtata aacggataga caagcagaac agggatggtc gccaccacta tgaccgccat 2953021 tttaatggtt tgctcaggcg gcgggctgcc cgaccccatt tcagacatat ccccctgcat 2953081 accgcttgat acaatgacga tttggcgcag aagcacctga attggccatt ttgctgaatc 2953141 atttaagtac aagatcgctg tcatatacgt gttccaatac gtgaccgcat aaaatagtga 2953201 aatcgttgcg atcgcaggaa gagacagcgg cagcacaatt ttaaagaata tgcccagatc 2953261 attgcacccg tcaattttcg cggactcttc caggcttgac gggatatttt gaaagaagtt 2953321 tttcagaatg atcaggttaa aggcattaat ggctgtcggc aaaataagcg cccagtaaga 2953381 atcgagcaat ccaagcgatt tgaccacaag gaaagtcgga atcatgccgc cgctaaacag 2953441 catcgtaaat acgacgagaa acatgagcgg ctgccggccg attaaatcac ggcgggataa 2953501 cccgtaagcc atcagtgacg aaagaaacat gctgaccgca gtgcctatca ctgtcacaaa 2953561 cacagaaaca agcaaactct tataaataat atctgttgaa aaaatgtagc gataagcatc 2953621 tagcgaaaaa gtggtcggta ttaaaataaa ttttttcgac acgacttctt ctactgtggc 2953681 aaaggatgct gcgataacat gaatgaacgg aagtacgcat attaaagcga acatcagcaa 2953741 gaaaccataa atcaacatat caaacagacg gtttttcagt gaatgtgcga tagctcccac 2953801 ctccctttgt aagcgttatc atatttttgg aaaccgagct cagcatgtga cgatatcgtg 2953861 tctaaaatgt agcaaatctg tgattgccat gtctataatc atttgaacag tgtccccggc 2953921 cgggcggggg ctgccgcgaa ttgagaccga taacaaaaga aaaagagcat aatcttagaa 2953981 aatgattatg ctccgttctc ctcctcgttc agaagttcag ccgtattgat ttgtggcgaa 2954041 aacccaagtt cattcacggc agattcaatg gaccatggcc ggcccggatt atcagagacg 2954101 gcgtaataag tgccataccg gatgttggtc tcaatggcgg ctttgaaaat cgacagcaga 2954161 tcggggtgag aaagcagtgt ctttttcgtc cgttcttttt catgcagcgt atccatttca 2954221 tctgtcacga ctgttccgat tcgaaggttg attactgata gcttattttc caaataaaac 2954281 aaatggccga tctgttcaga ggtcagcttt aatacaccgt acaagttttt tgacagcgga 2954341 taatcgcttg ttgtgatttc ccgtcctaag agcgagcgcc cgtctttttc atatacatct 2954401 gtgacatgat tgctgctggc gaacacgagc ttttgaatgc cgagctccgc tgccgcacgg 2954461 cacagataat agcttgccct atagaaaaca tccgtcattt tttcaaactc agcgatgtcc 2954521 ataatatcgt atttgatttt cacagcgagt aaattcaaga tggcatcggt atcttttgga 2954581 atcttcttca acagctcctc ataatttgcc gcgtcagcct gaatggaaga ggctttgcca 2954641 tcgaaatgat ctttatcaag cacagtcact tcatagtctg aaataagccc ttcagcaagc 2954701 agtctcccaa tcacaccatt tccgccggcg atcagcactt ttttcacgat gttcactccc 2954761 cttttttata gattgcccat tttcggcggg gctgacactt ttttggcact cacattctta 2954821 ggcttattca aaagtcaccg gcagctcctc aagcgcccga aatccaaaaa gcggccgata 2954881 ccgccattca aaatccgcaa gattaaggct gggcattcgc tgcagaagag tgttaatcgc 2954941 aatttgcgct tctaatcgtg ccagcgagga ccctaagcaa acatgatggc catgcccgaa 2955001 tgaaagatgc ggattaggac ttctcgtaat atcgaagaca tcggggttcg tgaatatgct 2955061 agggtctcga ttagccgctc ctaacaaaag atagacttgt tctccttgac ggatcgtcac 2955121 cccgcagatg tcaatatcct ctgacgcaac tctggctgtc atttgcgtgg ggctttcata 2955181 gcgtaaacat tcctcgactg cggtaccaat aagatctgga ttttctctca gtttcaaaag 2955241 ctgttctgga tgctgcagca gacaaaggac tgaattgctg atgagattga ccgttgtctc 2955301 atgtccggcg atcgccagca atatgcacgt agatgccgcc tcctcttccg tcagcttatc 2955361 cttttctctc cccttcaaga gcatgctgat catatcctgt tgagggtggc gttttctctt 2955421 ttgaatcagc tctttgaaat atgccatagc ctgcacagcc ataatattgc cctctgttaa 2955481 tgcctttctt gagcgggtaa aatcaatcgt ttgaatgaga ctcgcagccc actcctttaa 2955541 ttgctcccta tcttcctccg gtacacctat aatgttagct atgacaaaac ttgctaaagg 2955601 aaaagcaaag tccgaaatga cctccatctt ttttttacct tgcacttgat caagcaaatg 2955661 atggacagtt tcaatgatat acggctgata actctctgtc gttctcggcg taaacgctcc 2955721 gctggcaagc gtccgcaatc gtctatgatc aggctggttc tgaaacagca tcatttgatt 2955781 ttgcacatgt gaaaggtcct gatatttggt tgagctctca ggcagcgggg tgcggacttt 2955841 gaatctcgca tctttcaaaa tagcagccgt ttcttcatat cctgtgacat accagcccgg 2955901 gtattttaag aaactccctt tatagatagg atgaacagct cgcaatgtgt cgtaaaaaga 2955961 atatgggttt ttcaaaaact cagaagatgc agttgacgat gcaattgtca cgtgattttc 2956021 tcctttctgt tcaaaaataa aaacaatcga catcataccg attgctttta ttgattcttt 2956081 cagcttttcg cacttaaact agccttcatt tcttcgactg attcaacttc aaagcctaaa 2956141 tcactcagca ttttatgatc ctccgtctcc tcttgcccgg cagttgttaa gtagtctccg 2956201 acaaaaatgg agtttgcggc gtaaagccct aatggctgca atgtgcggag attgacctct 2956261 cttcctccgg aaatgcgaat ttcttttgat ggattgataa aacggaacag cgccagcact 2956321 tttaaacaat acagcgggtt taattcgttg acgccttcta acggcgtgcc atcaattgca 2956381 tgcaaaaaat tcacaggaat ggaatccgcg tcaagagcct tcaagctttt ggcgatgtca 2956441 atgacatcct gtttcgtctc cttcatcccg ataatggcgc ctgaacacgg agacagcccc 2956501 gattcttttg cgatttcaac cgtattgact ctgtcatcgt atgtatgtga ggttgtgatg 2956561 tttgaatggt ttctctgtga cgtattcaaa ttatgattat agcggtctac tcctgcatct 2956621 ttgagccgct tcgcctgctc tggcttcaac agtccaagac atgcacaaat cttcagtcca 2956681 tacgtctctt taatttcctg aaccgcatct acgacctgat ccacttctct gttagacgga 2956741 cctctgccgc ttgccacgat acaatatgtg ccgatattca gatcgtgcgc ccgcttcgcg 2956801 ccttcaagca gcgtttcctt attcaccatc cggtaagact caatcggcgc tttcgaaatc 2956861 gcagactgtg aacaatagcc gcagttttcc gggcagagcc cggatttcgc attcataatc 2956921 atattgagct ttactttttt tccgtaaaag tgttttctga tgtgaaaagc cccgtgcatt 2956981 aatagcaaaa tatcttcatc aggacaatgt aatattgaaa gcgcctcttc gtcagtcact 2957041 tctgctccag ccagcacccg gtctgcgagt tccatccatt gattcattct cataccccca 2957101 cttgattcat cagtaatgat agattgatat ggtcttttac catatgtaga accgtttctt 2957161 tcgtcacgtt ggcaagcttt ggcgtaaccc ctaaaatcgg cacaccgcat aagcgctcaa 2957221 tcatctcagg attggttttt tcatcttcat caggagagtc actgattcca ttgatgataa 2957281 ttccggcgat tggaagcccc atgctttctg catatttgac agttaaaaag gtatgattaa 2957341 tggttccaag gcgaggacgc gccacaataa tcatgggaag ctgcaacgct tttatgacat 2957401 gactgaccaa atagtcctct cccaatggca cagaaatacc gcctgcacct tctacgatga 2957461 agcattcatg tttttctcta atccgccccc aatggcttaa aacctcttcc atggtgacag 2957521 tctttccctc aagtttccct gcaacgtatg gtgcaagcgg cgccttgaag gcaaaaggcg 2957581 taatgtcttc atgagaaaga ctggtctgcg acatatcttt cagcaaactt gtatcactat 2957641 ctggatgatg gcgcgatatc ccgcttaaaa atggtttata caccccgaca tgtctattat 2957701 tgtctttcaa taaggcagca agaccgctgg atataaccgt tttccctact tctgtatcag 2957761 ttcccgtcac aaaaaaaccc ctcaaatgat gtgcagctcc tttccgattg aatgaaatgt 2957821 ttgcagcaaa tgatcaatat cacccatact gtggtcagac gtgattgtaa ttcgaatccg 2957881 gctttcaccc ggcgcaacgg ttggcggccg aatggcagga gcataaattc ccttgccctg 2957941 cagtttttca gcaaatagga ccgttttatg ggcatcgcca atgactacag gaataatcgg 2958001 tgtgtgatct cctttcacca cataacccat attcttcaga ctggttctga tcatgctgat 2958061 ataagaaaat aaaagctgtc gtttttccct gctggcttca atgatgttga aagcctcgtg 2958121 agcagccgca cagctggctg gcggaatagc ggtttgaaag ataaatgttc tggcatggtt 2958181 cagcaaaaag tcgatgaaga ccgctgatcc tgccgcaaaa cctccttccg cgccaacagc 2958241 tttgcttaag gtgccgataa caatgtcggg acaaacacca aagtattcac tcgttccttg 2958301 tcccgaatcg cccaaaactc ctgttgcgtg ggcatcatca acgaccacga aggcatgata 2958361 gcgtttcgca agtgagatga tctgatcaag aggggcgatt gtgccatcca tgctgaatac 2958421 tccgtctgtt acgataaaac ggcgctgata acgctgtgtt tcattcagct tgttttcaag 2958481 atcattcata tcaatatgcc gataaacaac tgtatcagcc ttagaaagtc ggcagccgtc 2958541 gatcatactt gcatgattga gctggtcact taaaatgaca tcttcctttt ctggcaagga 2958601 tgaaaggaca ccgacattgg ccaagtaacc gctcgaaaac agcagggccg cttctgtcag 2958661 tttaaagctg gcaatcttct tttctagctt ttcatgccag accgaattgc ctgtcgttaa 2958721 acgtgaaccg ctgcttcctg tcccaaattg ctgcaatgct gtttgggctg catcgatcaa 2958781 acgtctatcg cttgcgagcc ctaaataatt gtttgaggac cagaccgttt gattttcgcc 2958841 atcaatattc ctctctggaa ccggcgctcc atccattgac cgcaggttac gatgtacgcc 2958901 ggcttctttc attctgtcta accgctcgtt taaccaggaa tcaatcttca aggctcgtaa 2958961 cctcgtggat cgcttgtttc ataatggcaa ccatttccga gagctcttca gctgtgctgg 2959021 caagaggagg aagaaatgca atcacgtccc caagcggtct tgtcagcatt cctaactctc 2959081 tcatttttaa ggaaactttg tatccaatcc gccgatcagc cgggtaaggt tctttagttt 2959141 cctttgatcg tacaagctct gcaccgcaca taaagccaag ctgccgaata tccccaacat 2959201 gaggaagagc gtgcagatct tgaagaagaa aatggagctt tttacttttt tccgctactt 2959261 gttccacaat gttttcagat tcaaataatg ccagattttc aagcgcaacc gcacagccaa 2959321 gctgattgcc tgtataggaa tggccatgga aaaaggtttt taggttttca taatcatcat 2959381 agaatgcctt atagatgtct tcagtggcaa acgtaacggc aattggcaaa tagcctcctg 2959441 taatgccttt accggcagcc atcagatcag gctggacatt ctcgtgctcg cacgcaaaca 2959501 tttttcctgt acggccaaag cctgtagcga cttcatcaac gatcattaag acatcgtatg 2959561 ttgtacatag ctcgcgcacg cctgccaaat atccttccgg catcacgatc ataccggacg 2959621 cgccttgtac cattgattca atggaaagcg cggcaatttc ctcatgatgt tcctcaagca 2959681 gctgtgcaag ctctcggagg cactgatcac ggcactcatc aggatcaccg ctttcagaac 2959741 gatacacata aggaatcggg gccttgtaac tctcgaacat caacgggccg tatacgtggt 2959801 gaaaaagctc aattgaaccg acactgacgg cgccaatcgt atcaccgtga tacccgtttt 2959861 tcattgcgat gaatttttgt ttctcgggct tcccgatgtt cttccaatac tgaaacgcca 2959921 tttttagggc tatttccatc gcctctgcgc cgctgtctga ataaaagacc cgcgtgagct 2959981 tttttgggct gatgtcgatt aatgtttcgg caagctgggt tgctggaaca ttggtcatgc 2960041 ccaataacgt ggagtgcgca atttttccga gctgtttttt tatggcgtca tctagttctt 2960101 ttttgcggtg tccgtggaca ttaagccaaa ccgatgaaaa accgtcatag tattccttgc 2960161 cgtttatgtc tttgactttg attccagtcc cgctttcgat gattaagggg ttttcatcat 2960221 aatctttcat ttgggtaaat ggcagccaga ggtgcttttt acttttttct atcaaatcat 2960281 gagtcatgat cttcctccca ctctattaaa ataggctgct tctccaggtc atgtatgtac 2960341 gtgtttacat cattggatcc atcaataaaa aagactcggc agccctcttc agtcccgtat 2960401 tctttcattg ctgtaatacg ctgatagccc attttcttac ccgcaacata gcctgttatg 2960461 taatccggat cgtccgacca gcataattct gcaacgactg ccgggtgccg gcttaccttt 2960521 gaagcgagcg caagggcctc ttttattctt gaatgagctg gcacgtgact gtgaagcgcc 2960581 catttttcaa aattagcgtc cggccaatcc attctggaga cccgcacccc tttttctttt 2960641 gtttgatcca ttcgcttgcc tgtatgaata tcaaacaaca ccgcacccct gacatctgac 2960701 cattcaggga tttgttcata tgctttttca atcacgtctc gtgaaacgcc ttctttttcc 2960761 aataacaatc gggcaagctt ttgtccttct tccgggcagc tcacttcatt cgtatgcaca 2960821 ggcaatggct gaatggtttt tatcgattca tgtacctctt caaattgaat ttgcataaaa 2960881 tcaggttttc ctcttgaatg ggataaccct ttttctaata aagcattgac tgtatgcttc 2960941 atctcatgga aaggaataag ccgttctccg ccggatatat gctttccgcc gtcttcatga 2961001 gatccattca ttgaagccct cattctgaca ctataaaaag tttcttcttg catcatttct 2961061 cgccctttca ctgataactg aagaacgtgt agcgcttctc acctaaattg ttaaccaatt 2961121 atattcaaag gttaacaatt agaatatatt attctctcct gtttctgtca atagaagaaa 2961181 ggatcgattt atggcagttg gttaaaagga aacaaaaaga ccgttttcac acaaaacggt 2961241 ctttttcgat ttctttttac agtcacagcc acttttgcaa aaaccggaca gcttcatgcc 2961301 ttataactgc tgtttcgaaa tgtcccgaag cagaacggac cactcggtag caatcagcag 2961361 ctccctgtcc agcatagaca gctgtcaatt ctttttcgat tttgtccacg ccctcagccg 2961421 gcgttaaccg atcgtgtaca ccaacaagac taaggtgcgg gcgcggcgcg atcaggcttt 2961481 ggatctccga tgcggaaaaa tgctttgcaa gcgatgggac gtaataataa aagccgtgcc 2961541 tgtcaagatt ctgtgttttg atcagcacgt gatgatccac ctggctgcac aaatccacac 2961601 acaccttaat ccggtcatcg agcgccgctg tccaccacgc catcaaacct cccatagaca 2961661 tgccgatggt tccgatcctg tcaggctgaa catcagagcg tgactgcata tagtctaacg 2961721 cacttaaact gtcataaatc atcatccccc acatcacttt tccggtgaga agcatttctt 2961781 taaatatctc gctttccgct tttccccgcc gatctccaaa cccccaatga tcaatcgcaa 2961841 gaacgccgta tccgagtgaa gtaagctcat cagaaaaaga aggcgttttc aaataatccg 2961901 ctccctcaat cagctcactt tttcccctat catactggcc tccatgcgaa tgctgaaaca 2961961 atacggctgg gcacggtcct tctgttttct tcggcttcac aaaataagcg ggcgcctttt 2962021 catgtccatt taaatcgagc aggagcgttt caacgatatt ttcttctctt tcttcaatac 2962081 gtaatgtctc aacactgatt ggcctccgat caggcaaatc accaagcaat cgaaacagtt 2962141 gctttcttct ttcggctctc atcccatcac ccttccttat tcgcttactt cacatttacg 2962201 agacagatct gggttcccct ttatttttcc aacataaatc acatcattta ctaaatattt 2962261 agtaaatatt atggaatatt tcgaaaacaa ttattgtaac cgcttacttt tatatgataa 2962321 tatcaattta tcaaaaacag atgagttaat attttactaa atagatgaga gggataccca 2962381 tggttcgtat taaagatatc gccttgaaag ctaaagtttc cagcgcaact gtgtccagaa 2962441 ttttaaatga agatgagtcg ctttctgttg cgggcgaaac gagacaaaga gtcatcaaca 2962501 tcgctgaaga gcttggttat caaaccgttg ccaaacgccg aaaatcccgc gggcaaaaac 2962561 agcgggctca gccgctgatc ggtgtgctga gctgtctgtc ccctgatcag gaaaggcagg 2962621 acccttattt ttcttccatt cggaaaggga ttgaaaagga atgctttgaa caggaaattt 2962681 tcattacaaa ttcgattcat ctcggctcct ttcaggaaca tatctttcgg gaattggatg 2962741 gtgtcattgt catcggccgt gttcatgatg aagcggttaa gcatatcagc gggaggctgg 2962801 agcatgccgt atttatcaat cattcaccag atccgcaagc atacgattcg attggcatcg 2962861 attttgaatc ggcttcacgc caggcgattg atcacctttt cgacttaggc tacaaacggt 2962921 taggctacat tggcggacaa gaaaaagagc atacgctgaa ggacggccaa agcattcgca 2962981 gaacgattga agataaacgc ctgaccgctt ttttggagtc agccgccccc cagcctgagc 2963041 atgtgctgat cggagaatac agcatgcgtg agggctatcg cctgatgaag aaagcaatcg 2963101 atcaaggcca tctgccggaa gcattcttta ttgccagcga ttctatggcg atcggcgcat 2963161 taaaagcgct gcaggaagcc ggactgcaag tgccgcggga taccgcaatc gtcagcttta 2963221 acggcattga ggaagctgaa tttgccagca cgcctttaac gacggtgaag gtatacacag 2963281 aggaaatggg ccggacaggc gtaaaactgc tgcttgaccg tctcaatggc cgaacgcttc 2963341 ctcaacatgt caccctgcct acaacattaa tcgtaagaca aagctgcgga tgtacagcaa 2963401 aggaggtgac ataagcaaag attcatcacg atgataagga ggaaaagatg aaacacactt 2963461 ttgttttatt tctctctctt attctgcttg ttctgcccgg gtgttcagca gagaaaagct 2963521 cagcagatac cgcaaaaaag acgttaacca tttattctac aatgtcaacc gacagtgaaa 2963581 gagatacgtt cagaaaacta gcggcagcat tcgaaaagga acacagtgac attcatgtca 2963641 gccttcattt cccaggcaat gactatgaaa atatgatgcg tgtcagaatg gcggccaatg 2963701 atttgccaga tctattcgat acacatggct gggggaaaat caggtacgga gaatatacag 2963761 cggatctccg ggatatgaaa tggactcaag atcttgatcc caatttaaac agcatcctca 2963821 aaaataaaag cggaaaggtg tatgcctatc caatcaatca ggcaaaagac ggtctggcgt 2963881 ataatcgcaa tattttagac cgttacggca ttgctccgcc ggaaaccatg gatgacttta 2963941 tcaaagcact gagaacgatt aaagaaaaga gcaagggaag cattgttccc ttctggtttg 2964001 ccggatatga caaaagctca ttcgcccaat attacgacca attcgctaca cctcttctca 2964061 tcacagaccc tgcccataat gaaaaaaaac agctcatcaa cggcactttt caatggagta 2964121 aattcactta tttatcagaa atcctcaaac aaatgcagaa agaaaaattg atcaatatcg 2964181 acgccgtcac ggcaaaaaaa tcacagctca ttgaattaat ggcccaaaac aaaatcgcct 2964241 ttacaatgca aggcggcaca ctcggccaag acgttgccca gatcaacccg aacgtcaagg 2964301 tcggcattat cccgacacct gccatccatc ccggtgatga cccgatatgg atcggcggtg 2964361 aacgctacac ccttgcagca tggaaagatt cgcctcaatt aaaagaggca aaagatttta 2964421 tcgcatttat ggcccgcccg gccaatgcca aacaaatggc tgaagccaca tcgcttcctt 2964481 cagggctgac caatgtgaaa gctgatattt tctacgcaaa cgattatgag tattatcaag 2964541 atgtcaaagt cgagccttac ttcgaccggt tatacttgcc aaacggaatg tgggatgtcc 2964601 tgggcacggt tgggcaggag ctcgcggctg acattttggc gcctcaagac atttcgcaga 2964661 agctgggaag agaatataaa cgactccggg agcaatccga aacacaggga gctgaaaaca 2964721 atgagtgaga tcgcaaggga cgttcatgtg aaacaggtta agccaaaaaa gcagtcctca 2964781 ctttggtgga tgtacattcc tgctttgctc tccgttctgg tctttatgat ttacccgttt 2964841 gtgaaaggca cattgattac ctttacaaac tggaacggat tttcacaagt ctaccaatgg 2964901 gttggattcg cgcaatatga aaggctgttt tctgatcctg atacttggca tatcttaaaa 2964961 aacacgctgc attacgggct tggcagcacc ttttttcaaa atgtggtcgg gcttctgtac 2965021 gctctcctct taaatcaaag cattaaaacg aaagcggtaa caagaacaat tgtgtatttg 2965081 ccggtgatga tcagcccgct cattatgggc tacatttggt actttttctt ctcctatgac 2965141 ggaggcgcgc tcaacgattt gctcggggtc ttcggcatca gccctattaa tgcgctcgcc 2965201 agtccctcgc tcaatccatg gatcattgtc atgattaaca cctatcaata tgtcgggatc 2965261 gctatggttg tctacttagc cggtctgcaa agcattccga aagactacta tgaagcggcg 2965321 caaatggatg gcgcgaaaca aggccagcag ttttttacca tcacgctgcc gctgttaatg 2965381 ccctccatta ccattaatat agtcatcaac attatcggag gcttaaagct gtttgacgtc 2965441 atcattgcac tcaccgcagg cggccccgga aatgcgtcac aatccatgtc cacgtttatg 2965501 tatgatttgt atttcaaacg gcaggatgcc ggctatgccg caacgcaagg catatttatg 2965561 gcatttgtca ttttgatcat cagcttttgc gcgcttgcgt actttaaaag aaaggagacg 2965621 gaaatgtcat gagagccgcc cgtacaaaaa gcatgcggat cattacgctt cttgcagcca 2965681 ttgtggcctg tgcgcatttt attccttttt atatcctgct gaccacttca ttgaaagcaa 2965741 aaggagacta cagttcgaaa tggatatttc cagccgacat ctcctttcat aatttttcag 2965801 aggcgtggga gcgcgcttcg ctaggaaact cttttataaa caccatgatc atcacaggtt 2965861 tttctgcctt gttattaatt atattcggct cacttgccgc ctacccgctt gcccggcggg 2965921 aaacgaaact gaataaagcc gtttttgcct tgctgatttc cattatgatc atccctccgt 2965981 taacgtccat ggttcctttg taccgaatgg tcgtggacgc cggaatggtc aatacacacg 2966041 caatcgccat tttcatcaat acagcggctt acatgccgtt aaccgtattc ttatattcag 2966101 gctttatccg atcgaccatt ccaaaagagc ttgtagaagc cgcaagaatt gacggtgcag 2966161 gcatgctgaa aatctttttt acgattgtgt ttcctctgct gaagccgatc actgcgacca 2966221 tctgtatcat ttcttgtgtc tttatttgga acgactatca atttgccatt ttctttttac 2966281 aagatcaaaa ggttcagaca ttaacagtag ccatggcagg ttttttcgga gaaaacgcaa 2966341 acaaccttca tttagttgcc gcagcggcac ttatggcaat gctgccgatg gttgttctgt 2966401 ttttggcgct gcaaaaatac tttattgccg gcctgtcttc cggagcggta aagggttaac 2966461 attaaagggg gaagcaatat gaaaaagatt acatttatcg gtgcagggag cacgattttc 2966521 gccaaaaatg ttttgggaga ctgcctgtta acagaggcac tgaatggatt tgagttcgct 2966581 ctttacgaca ttgatcccaa acgcctgcag gaatcccagc tcatgctcga aaatctaaga 2966641 gaccgttata acccaagtgt ggccatcaac agctatgatg acagaaaact cgccttgcaa 2966701 aacgcaggct atgtcatcaa tgcgattcag gttggaggat acaaaccgag cacagtcatc 2966761 gatttcgaga ttcctaaacg gtatgggctg cgccagacga tcgccgatac agtaggcatc 2966821 ggcgggatat tcagatctct cagaacaatc ccggtcttat ttgatatcgc aaaagatatg 2966881 gaggaaatgt gccctgacgc atggttctta aactatacaa atccaatggc cactcttaca 2966941 ggcgccatgc tccgctatac caatatcaaa acaatcgggc tctgccacag tgttcaagtg 2967001 tgcacgaagg atttatttaa agctctcgga atggagcatg acggaattga ggaacgcatt 2967061 gcgggcatta atcatatggc ttggcttttg gaagtcaaaa aagacggcac agatttatat 2967121 ccagaaatca aaaggagagc gaaagaaaaa caaaaaacaa agcatcatga tatggtgcgg 2967181 tttgaattaa tggataagtt cggctattat gtcacggaat cgtccgaaca taacgcagag 2967241 tatcacccgt actttattaa acggaattac cctgaactga tcagcgagct gcaaatcccg 2967301 ctcgacgaat atccgagaag gtgcgtcaag cagattgaaa attgggagaa aatgcgggat 2967361 gatatcgtca ataataaaaa ccttacgcac gaacgctcaa aggaatatgg ttcaagaatt 2967421 atagaagcaa tggaaacaaa cgaaccattc accttcggag gaaacgtctt gaatacaggg 2967481 ctgatcacca accttccttc aaaagcggtt gtggaagtga catgcgtcgc cgacagaaaa 2967541 aaaattacac cgtgcttcgc cggagaactg cctgagcagc ttgcagcctt aaaccggacg 2967601 aatattaata cacagctgat gacaatcgaa gcggctgtca cacgaaaaaa agaagcggtt 2967661 taccaagctg caatgcttga tccgcataca agcgcggagc tttccatgaa ggacatcatc 2967721 tccatgtgcg acgatttatt tgcagcacac ggcgattggc ttccggaata caaataaaaa 2967781 ctaggggacc gctctcccct agttttttgg ttttgtttcg ccttcccagg ccatcatgcc 2967841 gccttcaaca ttgactgttt taaagccttg ctcatccagg tacttgcaga cgttcatgct 2967901 gcgcattcct gagcggcaga taaatacgta ctctttgtct ttatcaaggg tttccatttt 2967961 ttcaggaata tcccccatgc gaatatgaac ggcttgcggg atcatgcctt ccgctacctc 2968021 ttcatcttct ctgacatcaa ttaaatataa ttcttcgtcc gcctcaattt tttctttcaa 2968081 agcggctgtg ctgatttctt ttatttccaa agaaaacact cctattcaca gtgatcatgt 2968141 tcagtatatc aaagtcagcc gaacgattgc tattctgaga ctgatgaaaa aaaatcccct 2968201 tttggcaaag gggatttttt ctaggcttag tttgccacaa tattgacaag cttcccaggc 2968261 accgcgatga ttttccgaat cgttttgcct tcaagctgct ctttgacctt ttcatctgct 2968321 tgagcaagct gttccagctg ttctttcgtt gcatcggcag gaacctgtaa tttcgctttt 2968381 acttttccgt tcagctgaac aacgatttca acttcatcat ccacaagttt tgtttcatca 2968441 tatacaggcc aagcttcgta ggcaattgtg ccggaatggc caagcttctc ccatagctct 2968501 tccgctaagt gtggcgcgac aggagaaaga agcttcacga agccttccat atattctttc 2968561 ggcagttctg ttgctttata agcttcatta ataaagacca tcagctggga aatacccgtg 2968621 ttgaaacgaa ggccttcata atggtctgtg actttcatga ccgtttcatg atagacgcgc 2968681 tccaatgttt cacccgcgcc ttcaacgatt tttccattaa gctcaccgct gtcttcaata 2968741 aataggcgcc atacacggtc aaggaaacgg cgcgcaccgt ctaatcctga ttcagaccag 2968801 gcgattgaag catcaagagg tcccatgaac atttcgtaca atctcagcgt atcagcaccg 2968861 tgagaggcca cgatttcgtc aggattgaca acgttccctt tagatttact cattttttcg 2968921 ttgttttcgc cgagaatcat tccttggttg tacagctttt ggaacggttc tttcgtcggc 2968981 actacgccga tatcataaag gaacttatgc cagaagcggg catacagaag gtgaagcacg 2969041 gcatgttctg caccgccgat atacatatcg accggaagcc atttttccaa tttttctggt 2969101 gatgccagct gatccggatt gtgcggatca atatagcgca agaaatacca gcagcttccc 2969161 gcccattgcg gcattgtatt cgtttctctt cttccttttt tccctgtctc agggtctgtg 2969221 acttccaccc actctttaat gttcgcaagc ggtgattcgc ccgttccgct cggtttgatt 2969281 tcatccgttt ttggcaaaat cagcggcagc tcctcttccg ggacagctgt tgacgttccg 2969341 tcttcccaat gaatgaccgg aatcggctcg ccccaataac gctggcggct gaagagccag 2969401 tcacgaagac ggtacgtcac tttcttctca ccgtttttcg tttcttccag ccaagcgatc 2969461 actttttcaa tcgcttcctg tttgtgaagg ccgttcagga aatcagagtt cacgtgctcg 2969521 ccgtcgccag tataggctgc ttcctcaacg ttcccgcctt ttacgacttc cttcaccgga 2969581 aggccgaatg ttttggcgaa ttcaaaatca cgctcatcgt gtcctggaac tgccatgaca 2969641 gcacctgttc cgtatgatgc aagaacataa tccgcaatcc aaatcggcag tttttctccg 2969701 tttacaggat tgatcgcata cgctcctgta aatacgcctg tctttgtttt cgcaagatct 2969761 gtgcgttcta ggtcactctt tgattgaatt tctttgatat aagcttcaac agcttctttt 2969821 tgctctgccg ttgtgatgtt ttccaccaat gcgtgttccg gggcaaggac agtgtatgta 2969881 gcgccaaaca gcgtatctgg tcttgttgta aacactgtaa aggaatcatc atgtccatct 2969941 atagcaaaat gaacgtgagc gccttccgaa cggccgatcc agttgcgctg catatcttta 2970001 atgctttccg gccaatcaag ctcttccaag tcctcaagga gcctgtccgc ataagcggtg 2970061 attttcagca tccactgctt cattgggcgt ctctctaccg gatggccgcc gcgttcgctc 2970121 ttgccgtcaa tgacttcttc gttggcaaga acagtaccga gcgcagggca ccagtttaca 2970181 ggcacttcgt caacgtaagc aaggcctttt tcgtatagct ttaagaaaat ccattgcgtc 2970241 catttatagt attcagggtc agtcgtattg atttcgcgat cccagtcata tgagaagcca 2970301 agcgcttgaa tttggcggcg gaagttatca atattctgct tcgtaaacac agcggggtcg 2970361 ttccctgtgt caagcgcgta ctgttcagct ggcaggccga atgcgtccca gcccattgga 2970421 tgaaggacat catagccctg catgcgcttc atgcgggaca gaatatccgt agctgtgtat 2970481 ccttcaggat ggccgacgtg caacccagct ccagacggat aaggaaacat gtccagcgcg 2970541 taaaattttt gtttttcatt attatcaaga gtggcaaatg ttttgttttc aagccaatat 2970601 gtctgccatt tcttttctat ctctttgtgc tgaaaactca aagtaaaaac ctccttctga 2970661 ttgaatacgg cgtgtatggt tcaagtattg acgggaagga gaggattata ttcagaatat 2970721 tcccaaacta aaaaaaactc cctcatccca aaaagggacg agagactttc gttttcccgc 2970781 ggtaccaccc tcgttagcgc ggcatacgcc gcactcactt gatactttta acgcagttat 2970841 gcgtcagcgg cttttcaccg ctgcaactct gaggtgagtt cggaaacaaa cttgattgac 2970901 tttcaccagc cgtcaactct ctgcaacaat atctgtttct tactgctcct cttcattgtt 2970961 cttatcgcaa ccgtaatcta actgtatttt atagaattct gttcataagt gcaagcaggt 2971021 ttgtatacaa tgggaatgta ccctgaacgg gcggagattg aggacaatta ttcgggtgga 2971081 gttttggttt gacgtttgga ctcggccggt tcgccgccgc tgttcagttc tctcacaaag 2971141 tcaaaacttc tgagaacagc ttcaccgccg tagcctgaga taatggataa gatgacaagt 2971201 tgaattcctg aatcggggtc agcggataat acaagtaaaa tggaagccgt catgccgata 2971261 aaccaatctt ccaaaaatcc aaggtagata aaccgcttcg tcattctggg cttctccagc 2971321 ctgcctctct ttttcacatg accgagaatc cccatgattc ctccaattac acaagcaatg 2971381 agtacctgat gcagcatctt catcatcacc ttcctaaagc ccttatttcg taaagcgact 2971441 tcaggccatc cagccccctt aaacgattcc gatgattttc gatatctaca taccggcaaa 2971501 tctgtaaaaa gcttgtttct tccattatat gtgaacacat gatcggtaag cttgatgcat 2971561 tggattcatt tttcacccag tgacattgac ctagtcacct atttagcatg tagaaaacct 2971621 ttccgttcat atgttcaaat tctgttctta tttttagtgt atacgaggac aagccctaat 2971681 gacaaacaac aaactgcact tgcttgaatc agaacatgtg ttgtgctacg gttactgtag 2971741 aattcatttt taaaaagggg aatatcaggc tttcgcatag caagctgacg gcctaagggg 2971801 gatttatatg gctagttttc aatcatttgg gataccagga cagctggaag tcatcaaaaa 2971861 agcacttgat cacgtgcgag tcggtgtggt aattacagat cccgcacttg aagataatcc 2971921 tattgtctac gtaaatcaag gctttgttca aatgaccggc tacgagaccg aggaaatttt 2971981 aggaaagaac tgtcgcttct tacaggggaa acacacagat cctgcagaag tggacaacat 2972041 cagaaccgct ttacaaaata aagaaccggt caccgttcag atccaaaact acaaaaaaga 2972101 cggaacgatg ttctggaatg aattaaatat tgatccaatg gaaatagagg ataaaacgta 2972161 ttttgtcgga attcagaatg atatcaccaa gcaaaaagaa tatgaaaagc ttctcgagga 2972221 ttccctcacg gaaattactg cactttcaac tcctattgtc ccgattcgca atggcatttc 2972281 ggctcttccg ctagtcggaa acctgacaga ggagcgattt aattccatcg tttgcacatt 2972341 gacgaatatc ttatcaacat ccaaagatga ttatttgatc attgatttat ccggattggc 2972401 ccaagtgaac gaacaaacgg ccgaccaaat tttcaagctg agccatttgc tgaaattgac 2972461 cggaactgag ttaatcatta ctggcattaa gcctgaattg gctatgaaaa tgaataaact 2972521 ggatgccaat ttttcgtcgc tgaaaacata ttcaaatgta aaggatgccg ttaaagtgct 2972581 tccgattatg taaaaagatc ccgctcaccc agctggatct ttcagattgt tgacaaaatc 2972641 ctaaaatggt tttcatttta ggattttgtc atcttttcag cgtgattgaa aacccttgaa 2972701 gtctaggaag gacgagcata ggagcggagc gaatgttcta attcgtgagc accgaagcgc 2972761 aggcctgaca acgaatgcga gggtttgtcg acacgctgaa agatcccgct cattcggcgg 2972821 gatcttttat tatgaagaga ttgatgcctg cttatttgtt tctttagctg attttatccg 2972881 tttgtcatat agaagcgttg tggcaatact gatcagcagc aataccaaca gagataaaac 2972941 aagagcccta atgccgtaat gatcgacaag cactcctccg aacaggggac caatcattct 2973001 gccgcctgtc gccgcactgt tgacaaagcc ttgataaaag ccttctttcc ctttaggggc 2973061 aagctgattg gcaatagtcg gcacagcagg ccaaacaagc atttctccga tagtcaggat 2973121 caccatcgca gcgagaaaca tcggaaattg ctttgcagtc agcagcatgc tgaaagacac 2973181 aataaaaatg ataaagccga tgaccatttg cgcttttagc gactcggccc attttttcac 2973241 cacaaaactg acgagcggct ggccgagcac aatgagaatt ccgttaaccg tccacagcac 2973301 gctgtataag gaaagagata ttccaatgct ttgtgtgtac gaagcaattg tggttgacca 2973361 ctgagaataa gccagccatc cgagtacata gcctccgctt aaaatgatca gtgcggcaaa 2973421 ttttgctttg ctgttcacag catcataatc aagcacggat gtttgggatg catcgcccgt 2973481 ttgaatattt cgaaatccga aatatacaat aaagaaaaag atcagataca atacggcatt 2973541 tgccaaaaat acatatgaaa acgagaaaga tgccacgaca ccgccaagcg ctgaaccaac 2973601 ggccacgccc gcgttttgcg cgacatatat cgcattaaat gccttccttc ccccttcagg 2973661 ccataccgat cccgccattg cgtagcttgc cggaaaaaca acaccggagc caaagcccac 2973721 aatcgtcagc agcacaatat aggctggcca atcatgaaaa aagacaagac ccatcaggct 2973781 tgctaacgta atggctatcc caagcataat cgatttaaaa ccgccgattt tatcaaacaa 2973841 aaaacctccg cataaattgc cagccacact ggcgccggaa ttcagcatca ggacaagtcc 2973901 ggctactgtt aacgactttc ctaaatgatt atggatataa atcgtattca gcggccataa 2973961 aaaagaagca cccgtcacat tgataaacat tccaatgact aaaattttaa gagcacgcgg 2974021 catactcatc cccctttctt acctaaaaaa gctcatgaaa aaaacgaaac ctaaaacggc 2974081 tccgtacgaa tccagttatc atagcacatt cattctatct gtctctctca catttttcaa 2974141 ctgatgagcg tgaaaaaatc taacaaatat tgtttgaaaa atgtaaaata aatagaaaaa 2974201 ggggtcatat tatggaaatg gtattagcat tcttaggttt tctggcatgt ctcattgcac 2974261 tgggctatgg attatatcac cttgtcagat atgtactgaa aaaggaaaaa cgtttctcaa 2974321 agagactttt ttggccgctt ttcattggag gccttgtgct gctctttacc ggggcagcat 2974381 tggcagaacc tgacactgcc gcagcaaatg ccgagaaaaa atattcagcg ctaaacgccg 2974441 aatataaaaa cctcacaaaa gagcacgaag aacttgagaa agaatataaa tctgtcagct 2974501 ctgaagcaaa gaaattaaaa gacaacaaag aagatcaaga caagcttgag aagcttaaaa 2974561 acgaaaatag cgatctaaaa aagactcaga aatcattaaa agctgagatt aaagagcttc 2974621 aagaaaatca aaagcagctc aaagaagatg caaaaacggc aaaggctgaa aatgaaacac 2974681 ttcgacaaga taaaacaaag cttgaaaatc aattaaaaga gacggaaagc caaaccgcca 2974741 gctctcatga agacactgga agttcttcaa acaatacgag taaaagtgat gaaaccaaaa 2974801 cagctgacaa agcagaaggc tgtaatatca aaggaagcag aaacggcatc taccacacgc 2974861 caggcagtac atactacgac cggacaaccg atccggctga aatgttttgc tcagttgaag 2974921 aagctgaagc cgccggttat cgggcgccaa aacgataaac aaaaagctcc agaatgtctg 2974981 gagctttttc tgtttcacaa cgacgattta atgaccttct tataataaag aactgacaga 2975041 aaaccaaaaa tggagtagag cgcagtatat aacaccatca ccataatcat aggcgcccat 2975101 acctctgatc cgaataagaa ccagccggat tggacggcaa agtaactgtg gaagaggccg 2975161 acaacgagcg gaatgccgaa gttgtacatt tgtttgatgc gtatcccctt tatcaggtcg 2975221 ccctgcgtaa agccgagttt tcttaaaatt gtatagctcg gtttttcatc ttcactttca 2975281 cccatttgtt taaaataaag gatacaacct gatgtaatca ggaacgttaa ccctaagaag 2975341 ccgacgatga acatcaccat accaaacagt gatttttgcg cagcgcttgt atctagtctt 2975401 gataaatgct cgtttttctt gttcacctgt tgaaaaagct catttgcttt ttccatttga 2975461 tcgtcatgtt tcacattgac gccgataaat gtagattgcg ccagctgaat gcgggggtct 2975521 ttatccttgt ccagctgttt aaacaggctg tcatccacaa tgacagcggg catgcccccg 2975581 cttgtaaacg tgtaggacac aagaaactct tctcttaatc ctttatattt taatggctgc 2975641 gtctcgtgct tgctttttac tttaataaca ccagagtcct tgaaaaccat tattttttgc 2975701 agcaagtcgg tgtatcctga gaaaacggct tctccagccg ccacatcgac tccttttaca 2975761 tctttgtcgc taacaacagc aagctgcata ttgccgggat cgccctgcat ctctttcgga 2975821 gttccatcca taatatttgc aatgtcaaca tttgcttgca ggacaggtgt tgcctttttt 2975881 acaaacgaga tgttgctttc cctcaatttg ttttcaaata acttggcatc tttctcattc 2975941 atgaatgaaa aatcagccgc tacattttgt tcagcggtct tttccgacga gtaatacgag 2976001 atgtaagcaa gagataacag cccgatggcg agcgctgaaa cggttgtaat aatcgtcagc 2976061 agcagcgcat tcgatttcat tctgaacatg atcgaagaca gtgacagaac ctcagaaata 2976121 tttaagtagc cgcccttgct ttttcgaatg atattcgaga taaacgtaac tgatccttta 2976181 taaaacaaaa acgtcccgat aatgacgctc cccagaatga agctcatcgc aacaaacagt 2976241 tcattaatgg tcttaaattt tccgccaaac agctcagaag acacatagta tcctgtcaaa 2976301 atcaacacga tgcctaaagc gccgatcagc atttggaaaa atgatatttt cttcactttg 2976361 tcttcagtgg aggacgttac tttaaacaaa gataaaatac tctgtttttt gataaacgta 2976421 taattcatga tcatgatcaa aaggtaaatg ccgcagaaca caatgaccgt ttggaccaag 2976481 gcctgctcag aaaaatgcag tttcgcatcc gctttgacat cgacaatttt gaacagaatc 2976541 atcaagacaa gcttcgatat cgaaaacccg gccgctaccc cgatcgctaa tgaaccgaaa 2976601 tacagcatga cattttctgc acttaagatg cgaaaaattt tatgcttcgt cattccaatt 2976661 aattgaaaca gcccgatttc tttactccgt ctcttaataa aaatcgtatt ggcatataaa 2976721 atgaagatcg ccactacagc cacaagcaaa atcgaagcgg ttttaatagc cgcggctccc 2976781 ttgattgaag ccttcacttc gttaattgct ggatcatact gcagcgtgac aaaggcgaaa 2976841 taaagcgcca cgctaaagat gagcgcaaac acatacaaat agtaattccg gagattcttt 2976901 ttcaaatttc gcaggatgag ctgattaatg ttcatgctgc accccgccta acacgccttg 2976961 cgttttcata atatcctgga aaaacgtttg cctgtcctgg ccccctttat tcagctgtgt 2977021 atacatttgc ccgtccttaa taaaaatgac tctgccgcag tagctggcag cgacgggatc 2977081 atgggtaacc ataataatcg tcgcgttgcg tttttgattg agctggctca gcttatttaa 2977141 tagatcggag gccgatttcg aatcgagcgc gccggtcggt tcatcagcga aaataatgct 2977201 cgggtcatga ataaacgctc ttccagcgga tgttctctgc ttctggccgc cggaaatttc 2977261 attcgggtat ttatcccgca attcatatat tcccagttcc ttggcaactt cctcaaactt 2977321 gcgattggct tccttttttg atagtttcgt gatcgataaa ggcagaagga tattctcttt 2977381 cactgtcaat gtgtctaaca aattgtaatc ctgaaagata aagcctaaat gctgttttct 2977441 aaattcagcc agctgctttt ccttcatagc cgtcatgtca tttccattaa tatgaatggt 2977501 tccgtgactg acctgatcga ttgaggacag aacgttgagc aaagtggttt ttcccgaccc 2977561 ggaagcaccc ataatactga cgaattcgcc cttttcaatg tgaatatcga tgcccttcag 2977621 cacttcctgt ttattcagct tgtttccata actttttcga attttattcg cttctaaaat 2977681 caccatttac gcagtctcct ttatattgga taatctcatt ataaaaagga atgccgggct 2977741 tttccttcga tacggcgaac aaaaaagaaa agcatgtgac attttcgtca cacgcttatg 2977801 acatgttcaa attgattccg tattggaaag gttaatgtaa aaactgttcc cgcaccaaac 2977861 tccgactcaa catcaatatg gatcaataac ggcgccgctg ctttttttgc caagtacagc 2977921 cccatgccag ttgacgcttg atcatggtga tccgttgtgg atgtaaaccc tttatcaaaa 2977981 atacgcggta catcttttgg atcaatgccc ctgccacaat ctttcacttg gagctgcgtc 2978041 tgttcccctt tttgaaagct tttgatctcg atttcagagg cttcgctgta tttcaccgcg 2978101 tttgtcagca gctgcctgat gataaacgcc agccattttg catcgctcag cacttctttg 2978161 gcctcgagct gtatgtcaaa accgatccct ttttggatac accacgattg taaatctttg 2978221 atttctttaa agatcaaagg ctgaagctga atgaattcta ctgacaggtc gttttcaata 2978281 aatgaaatgc gtttttgatg aagctgctga tcaagaagca ggtgaatacg cagccattca 2978341 tatgacagct gggatttcag tgctttttct tccattctat caatgattaa atgcatcgct 2978401 gttaatggag ttttgacctc atggatccat gccatcagct catctttttc attttccaat 2978461 gctaagcgat gccgtgctgc ggtctgcttc aagtgttctg tttgcccggc aatgcttctt 2978521 tcaaccattg cttcaaacgg cgtttccggt tcatttatgg ctgtcacatc gagattgttc 2978581 tcccatgttt tcaagctttt ataaaacgct gtttctttcc gatagcggaa ccaaaggaat 2978641 atgataaaaa acaagatgca caaatacacc atataaagta cattcccaaa tgatatggaa 2978701 ggatcgacaa aagcaatgaa cagcatcaaa gcctgctgaa acaaaaacgc ggcaatccag 2978761 ctccgccttt cgataaggaa tgctttaatc atagaacttg tcctcttcct tcgcgatgta 2978821 gccctggccc acctttgtct cgatatatgc accaagctgc agggcgtcca gtttttttcg 2978881 caggcgattg acattgacgg tcagcgtatt atcactaaca aaacgctcat cgttccacaa 2978941 gcttctgatc agctcttccc ggctgacgat cttgtttttt tgctctatta attgttttag 2979001 aatgaacatt tcatttttgg tcagttcaac agatcctttg tcattgctga cgaggttctg 2979061 ctccgcgtct acagcagcgc cgcaccacgt tttaatcgta ctcggctccg tattataatg 2979121 gtgcacacgc cggaacatcg cttggatttt cgcgatcagc acatcaaaat gaaatggctt 2979181 ttgaataaag tcatctgccc cgagctgcat ggacatcacc atatcagcag gatgatcccg 2979241 ggaggataaa aagagaatcg gaacatttga ccgggagcgg atcagacggc accaatgaaa 2979301 gccgtcaaat ttaggcagct gcacatcaat aatgacacaa tcaggattaa ccgccgcaaa 2979361 ttcctgcagc acctgactga aatcctgaat gccgtataca tcataggacc atcccgttaa 2979421 acgatccttg atttcatgaa acagcgattc atcatcttca atcagcaaaa gtttaaacaa 2979481 tcgactcacc gcactttttc cttttttatc aagtgtatag caaaacgcca gcatgcgcta 2979541 tagaaaaagc cggctgtctc agccggctcg ttcgcattat aattctcttc tcaacgctgt 2979601 cagcacgttg gttttggtag cttttctcgc cgggttcatt ccggaaatga ctgcgacccc 2979661 tccgcaaatc acaacggcaa tgatcacaag gctcgccggg atgtaggaga atgtgtaatt 2979721 caaatcgccc gcatcgccac cgcttgtggc cgcaagaatc atcggaacgg ccaggttgac 2979781 aaggtagctc acgccgtaag aaatgataat cccaatcaca cagcctaaaa ttccgatata 2979841 cgcgctttcc atcaagaaca ttcggcgaat gattgacggg ctcgccccaa tcgctttcat 2979901 aatgccgatc tcttgcgttc tctctgtcac cgccatcgtc atcgtgttaa aaatgccgat 2979961 cgctgaaatg ataactgcga tacatccgac aaagatcagt ccgattttga agaccatgaa 2980021 gaaggtattg gctccctcaa gttcagtagt cactgatgtg acatagtacc cgtcatctgt 2980081 tagatcattt gtcagctgtt ccacattctc aaacttatca gcaaaaacac caatgttcgt 2980141 ttcaacattt ccgcctttga aatctaagaa ttccgaaaaa tcttttttga attgatcact 2980201 gataaaaata tttgagtcct ccatccagtc ttgagatggt ttttttgtaa taccgacaat 2980261 tttaaagtca tatgtttttg tttttgtaac atcccctgtt ttagaatctg tcttcgatac 2980321 acttagttca attgttttat ttagaatatc tttcgtatag ccctttggtt cttttatatc 2980381 ttctggattt ccttttgctt cctcgatttt tttgttatat tcttccgatt cttttttcgt 2980441 taataatctc tttgcgaagt cgtatcctac tacgatttca ttttccgact ttgcgactct 2980501 tcccttttcc aattccatat tggcctttaa ttcatcattc atattagtaa aaatgagatt 2980561 tgagctttca tttgtacgat tgcctaaagt agctttgttt ggttcataca cttgcgttct 2980621 ttctacaact gaccttacgt gatcatactt ctctaaatca gcttttttaa tcggcttgtc 2980681 tccttccttg cccattacgc tgactttcgt tacaatctgc tggctcattg tcatatctgt 2980741 aatcgtcttt tgaatcccaa atccaacgga cgacaacaca accaaaaacg cacacgccat 2980801 tgttgtcgcc agaatcgtca taaagacgcg aagcctgttt ttcttcatat ttcttctgat 2980861 aaaatgaacc tgatccttaa acctcaacgg taattcctcc ttttagcaca ccatcatgaa 2980921 gctgaaattt tgaatgtccg atagaagcga cttcatcatc gtgagtaatg atcacaaatg 2980981 taatgccacg ctcacgattc agctgctgga tcaattccag cacttcatgt tccgtttctg 2981041 aatcaaggct tcccgtcggc tcatccgcta agataatcga aggatttaaa atcaatgctc 2981101 gagcaatact gacacgctgc tgctggccgc ctgacagttc attcggataa tgagcggcgt 2981161 ggttttccag accgacgcgt ttcagcatgt cctgcacctt ttgcttccgc tcagatggct 2981221 tgattccttt taacgccagc ggcatttcca cattctcata cgtcgttaaa cccgggatga 2981281 gctgaaagct ctgaaaaata aacccgaaat ggtcaagccg aaattgcgcc cattcctttt 2981341 cattaaaccc cgtaacatca gtgccattaa tgacaatccg cccttttgtc ggcgatatgt 2981401 agccggaaat taaattcaaa agcgttgatt tccctgagcc gcttcgtccg acaatgcagg 2981461 cgatttcccc tttcgccacg ctcaatgaaa catccttcaa tactggaact tcattctcac 2981521 ggcccttttt tccgatcgtg aaagaatggt cgatatgctg aacatcaatc atatgttctc 2981581 tctcccttac aaaagtttca tttttttata aatcgcaaaa taactaatca agaaaccgat 2981641 taccgcacct gtacccatgc caatgagata accggcaaag ctctcgcttg cagtaaatcc 2981701 aaaatagccg aagcccatga ttcctatgat aataacgatg atctgcaccg ggcggttaag 2981761 cggcttccat aagaagaaat atccgtttct ttcattagac attttaacaa agctaatata 2981821 gccgatgatg taaaaaatga tagtcatgat agccggaatg actaaataat atggtgaatt 2981881 ctcagcccat ttcgagtcta cataaattat cggaatgaaa tactgcaccc atttaggtac 2981941 tggaccatgg ataaaatcta ttgatccgcc aaaaaggatc tcgaggttga tcacaggcag 2982001 gctgatgagt aaaaacggcg aaatggccac ggtaaatgag actagaagct gtgcgaaact 2982061 attgcctgtc aaagctcctc cggccataac caaagaataa gccagcatgc taacaataat 2982121 cattcccaag ctgtaattgt gaaaataaac ggcctgatct ggcttcaaaa gcatgatcag 2982181 caaaacagac aaaacataac ctatgagctg cggcaccaca atcaccattc cgccggtaag 2982241 gaacttcgca tgaaatatct gccctcgtgt atatggaagg cttaatgtaa aatcaaagaa 2982301 gctcttgcta cgttcaatcc caagctggct gaccgccaaa acgactcccc aaatccaaaa 2982361 caatgagata aatgagctat ttaaataatc aacgctgaat acgcaggggc cgacccaatt 2982421 ttcttttcca gtgacacagc cttgatagat gagatacata tttaaaattg ataatggatt 2982481 acctaatata aaaaccaaaa tggtgataac taaggcgact ttattctgcc gccactcttt 2982541 gtaaagcagt ccggaatccg gcaactcact tccctccaaa cctaaggcat ttcttacact 2982601 tttgttttct tataaataga gaagtagctc acaaagaatc cagccactgc tccaatgatc 2982661 atacccaaaa tataaccaat aatggaatgt ccggtatagt atccaaataa accaaatcca 2982721 aggatgccga aagccataac cagaatttgc accgggcgat ctaatctgtt ccataagaaa 2982781 aagtgtccgt tccgttcact tggaagcttc ttgaagctta taaagccaat caagtaaaat 2982841 agcatgctca ttacggctgg aatcaataaa agatatttac tgttaatcag ccattcattt 2982901 acaacgtaac taatcggtac taggttcgat aaattgcttg ccagagagaa ataactctca 2982961 ggggaaggga atatttccca tatattcgca ccaaaaacaa cttctaggtt tccaaccggc 2983021 aatgcaataa ttaaatacgg caatatagct gctgaaaacg ccgttaacag ttgggcaaaa 2983081 gcatttccag ttaacgctcc ggcggccatc accagtgaaa aagccataaa acttatcacg 2983141 attactccaa tgctgctgtg ctcaaaaaag tagacgtgtt cagggttata gacaagaatc 2983201 agcagccatg caagtaaaaa gccaatcaat tgtgacagca caatcacaaa accgcctaac 2983261 caaaattttg tctgaaaaat ttggcttctg ttatacggga ggcttaatat aaaatccatc 2983321 gtgcctttcg aacgctccat tccgaggaag cagaccgcca aaatgacacc cggcacccag 2983381 ttgatatcta tcagattgct tatggaataa ttcacaataa aatcacaata ttgcgggtct 2983441 tggcgatcaa gacacccttg ataagacaaa tacgtattaa cgatagaaag cggatttgcc 2983501 aatactaaaa acgcgatact taacaaaatc accacttgat tctgcttcca ctctcgatag 2983561 aggagacctc ggtctaccat ctccgcttcc ctccaaactt cgcaatgaac acttcttcca 2983621 ggttgacagg aagctcattc cacacttttg gcttcagctc tctcaaaaag ctctttttct 2983681 cctcatcgct tttcggaatc agcactgtgt aaaacacgcc ggcctgatcg agcatcggaa 2983741 tgttttgctc tctgatggcc aaattgacat ctgtatcgaa ggccatttga attttaatgt 2983801 attcttcttt taactcatca agatccatga cgttggtcag gctgttatct tcaagaaaac 2983861 caattcggtt gcacatccgc tctatgtctt caagccggtg ggacgtaatc aggatgctcg 2983921 tatcacgctc tgccacttca tcgaccatca gctgcagcac atcatgcctt gtcaccgcat 2983981 caataccatc cgtcggctca tcaaggagga tcagcgccgg tctcgccgca aacgacagaa 2984041 cgagcgatag ctgctttttt aagcctgtcg acagctcacg gtattttttc gtttccggaa 2984101 tttcgtatct gttcatcagc tcattcgcgt acgtgacatc aaatttcgga tatattcttc 2984161 tcaaaatatc gactaactgc ttgtatgtat acttatcgta aaacggattt tgaacaggca 2984221 tgtagatgat attttgtttg actttcgggt gctttttgat ttctacgccg tcaaataaaa 2984281 tcgttccgct gtcagcgaaa atgatttgct ggattaagcg aagcatcgtc gttttgcccg 2984341 atccattgcg tccaagcaat ccaaagattt ctcctttttc gattgttaat gaaacatctt 2984401 ttaatacttg attgccgtca atcgcttttg acagctgccg cagttcaatc attttttttg 2984461 cctcccttca catcagcgct gatttccttt atccattcgt gcagtttttc cagctcaacc 2984521 cctgcatagt gtgcatcgat gatgagctgt ttgagttgct ctttaatcat cgtcatcttc 2984581 ccttcaacca gtgtcgtttt tgcattctcc gatatatagg tccctctgcc ccgcagcgtt 2984641 tcaataatcc cctctcgctc aagttcttta tacgctttgc tgacagtgtt cggattcgca 2984701 ataatgatcg ttgccaattc tctgacagaa ggaagcttat caccaggctt catgatccct 2984761 ttcaaacaaa gctctttcat ttgctgaata atttgttcgt aaatgggtgt tgagcttctt 2984821 ggatcgattt gaatcattta cttccctact ttctatacga tctgaacctt ttatagataa 2984881 aaatgatcaa ttatactttt ttgccattca aaaccgatca tcacaagaac aagaaaaaaa 2984941 gaacaagcga tcacagatgc cgcaatcagc attggcacgt tacgtttgtt tcgtttttta 2985001 tgtttcataa ctgcctccct taatgtcaat atataaatga ttttatatta gtgtctatag 2985061 tgtattactt caattagtac acttaataca ataaatactt tgactcacaa agtcaatcct 2985121 ttttttacaa aaaaacggac ccttttaaaa gggtccgttt tcctacacat caagagggtg 2985181 ctgcaggatc atattatttt gcaaagattg aagctgaagt ctcattctgt acagctgttc 2985241 tctctgctga tcatttgacg acagccatag tttattcaag gcatttaccg catcttctag 2985301 ctgcatttgt gcatcactat attcttgatc gttataatgc tcttgtttag aagcgatttt 2985361 cagctgttct tcagcataat cataggcctg catacattgc tggagatgtt catctactga 2985421 ttgtcttgtt gccacagtaa cccctcctct tggtaatgga aatcatccat cattcatatt 2985481 gtagcctcat ctgactttat tcaataaagt aatttatggt cgatattcat ttgttctctt 2985541 gtgaaatgcg tgctacaatt ttaggatgca atcgtacgca aggaggcaca tgaattgtga 2985601 tgcagaacaa tccttttcct tattcaaata cggaaaaacg ctatcataca ttgaattatc 2985661 atctcagaga acatttcggc cataaggtgt ttaaagtagc gcttgacggc ggttttgact 2985721 gtccaaatcg ggatggcacc gtagcccacg gaggctgtac gttttgcagc gcagcaggct 2985781 ccggagattt tgctggaaac cggaccgatg atttaattac gcaattccat gacatcaaaa 2985841 accgcatgca cgaaaaatgg aaggacggca agtacatcgc ttattttcag gctttcacaa 2985901 acactcacgc cccggttgag gtgcttcgtg agaaattcga atccgtcctc gccttagatg 2985961 atgtggtcgg catttcgatc gccacacgcc cggactgtct gcctgatgat gtcgttgatt 2986021 acttggcaga gctgaatgaa cgtacgtatt tgtgggtgga gcttgggctt caaacagttc 2986081 atgaacggac tgcacttttg atcaaccgcg cacatgattt taactgctat gtggaaggcg 2986141 tcaataaatt aagaaaacac ggcatacgtg tctgctcgca tattatcaac gggctgcctt 2986201 tggaagaccg ggacatgatg atggaaacgg caaaggccgt cgcagatttg gatgtccagg 2986261 gcattaaaat ccatctgctt cacctactga aaggcacgcc gatggtcaaa caatatgaaa 2986321 agggcaagct ggaatttctt tctcaagatg attatgtgca gctcgtctgc gatcagcttg 2986381 agatcattcc gcctgaaatg atcgtccacc gcattacagg tgacggaccg attgagttga 2986441 tgatcgggcc aatgtggagc gtcaacaaat gggaagtgct tggcgccatt aataaagagc 2986501 tagaaaatcg aggcagctat caaggaaagt tctttcaacg gcttgaggag gaatcagcgc 2986561 tatgattttg aagaaaattc ttccttacag caaagaactg ctgaaaatgg ccgcgggaga 2986621 gggagatatt gtcgtagatg cgacaatggg caacggacat gatacacagt ttttagcgga 2986681 gcttgtcggt gaaaacggcc atgtatacgc attcgacatc caagaatcag ccgtggccaa 2986741 tacaaaggaa cggctcggtg acatgtatca agcgcgaaca acgttatttc acaaaagcca 2986801 tgataaaatc gctgaatccc tcccgcctga aacacatggc aaagtggcgg ccgcggtatt 2986861 taacctcggc tatttgccgg gcggggacaa atcaattacg acaaacggca gttctacgat 2986921 caaagccatt gaacagcttc tcagcatcat gaaagacgaa ggtctgattg ttctcgtcgt 2986981 ctatcatggc cacccggaag gcaaagctga aaaaaacgac gtgctcgagt tttgccggga 2987041 cttggaccag caaacagccc gtgtattaac atacgggttt atcaatcagc aaaatgaccc 2987101 gccatttatt gtcgccatcg aaaaaaaagc tcagatcagc aaatgatttg agcttttttc 2987161 tttgaatttt tcatccagga cattttttga aatttccggt aggctctgcc gttgatataa 2987221 aagaaaaggg aggtttttcc gctggctttg atcagcttct ttgcgagccg gcccatttcc 2987281 ttttggcctg ccactttatc atctgacaaa taaacgccaa gcaagccgcg attgattaaa 2987341 cgatggaagt tttcatgcgg aatgccttgt aaatgctcgt cggctttatg gataaagtgt 2987401 tcaagccggt ccatcatctc ttcatgagac tgataatacg agcagaaatt caagtctcct 2987461 tccagcaagt cctcctcttg atcaatcaaa taatcaagaa gaatatgaag accctgtatg 2987521 taaggaaaat aactgtctcg gattttttta gcggtgcttt ctgtgaaatc aggctggaac 2987581 gaatacgcaa ccagacagaa aatgcctaac gttgagcctg cacaggctga aaattcatac 2987641 cattccatct caggcagctc tgattcatat tgagtaaacc acttttcaag ccgcggaaca 2987701 cgctcatgct caataacgtg cttatgcacc tgcaaatcgc aataatagcc gcacagttca 2987761 agcagataag gtttaatcat gtcatagtgc tcaatggagc cgagaacacg ctggcacgtt 2987821 ttaaccagtt catgcaaata tccgctgtca tcctgttctt ccctgaattg ataatagttt 2987881 tgcagttccg ccccaactgt cagtgcgtcc tgcattgagg catggagcat ccgaaaatcc 2987941 tgcgggtcca gcgaggtgct gcggtcacac agattgtcca aataatcact aatcgtttga 2988001 tacgcgatga taaactcgac acatttctgc ttttggctgc ctgacaataa ggccagtatg 2988061 ccgccgcctt cacagtgaaa cgttttgtcc cgaatacttg cggttgcctg tgctttcaat 2988121 tcactgttat gaatcgattc tgatttttgc ttccatatgt ccagctcttg atgaacgagc 2988181 ggaaaaatat ctcgatatac ctttgccatc aatccaaaag gatgttccgg tactgtcaac 2988241 acatgcaccc cctactagtt caaatatatt gatcagtaaa cgctcttgct gctttaaaaa 2988301 catcttctct ctcgggttca ttgaagatct catggtaaag cccttcccac tctctgtatg 2988361 ctttattatg agaagcaaca ccattaaacc acttgatgac catcgttttg tcaacaagct 2988421 tgtcatcacc ggcttgcatc acaagaagcg gaactttcaa aaatgcctct gtcggcacca 2988481 ttgccgattc aattgtcttt aaaagctctc tgtaccatct gacagaaact ttcctgacgt 2988541 ataacgaatc attttggtca gcttcgatga cgtcctcatt gcgcgtcgcc atatcaattg 2988601 ataatcccga atcaacctta agtgacggag cgatgacatt caggcctttt gatgcaagat 2988661 caagcgcttt attcacttta atttgcagtc cgagacacgg tgatgataaa ataattcccg 2988721 taatccgggg atttctttgc tgtttaaccc attcaatcgc gaccagaccg cccatgctgt 2988781 gacctagaag aaaaaccgga agatcaaagg ttcgcgcttt atctatccaa gcatctactt 2988841 catcaatgta ttcttgaaac gagcgaatat gccctctcgc tcttgtcgtt gttccctgtc 2988901 caggcaaatc gcccatgaca acgtgataac ccgaagaccg ccacatttca atcagccatt 2988961 tatatcgtcc gtgatattca cttgccccgt gaatgattac aatcacggca acaggtctgt 2989021 ctgctttcca ggtccacatg atcttcacct catacgaaat ttaaatagag aaagaaggat 2989081 gaatcttatg atctaccctt ataaggaaca caagccagat atccacccaa cagcctttat 2989141 agctgataat gcaacaatta ccggtgatgt cgtgatcgga gaacagtcca gcatttggtt 2989201 ttctgttgtc ataaggggag atgttgcgcc gaccagaatc ggaaacagag tcaatatcca 2989261 agatttaagc tgcctccatc aaagcccgaa caagacgcta ctcattgaag atgacgccac 2989321 gataggccat caggttacac ttcatagcgc tgttatccgc aagaacgcct taatcgggat 2989381 gggctcaatc attttagacg gagccgaaat tggcgaaggc gcttttattg gtgccggcag 2989441 tcttgtcccg cccggaaaaa tcattccgcc tggccatctc gcctttggcc gccctgcaaa 2989501 agtcatccgc cctttgacgg aagaagaccg aaaagatatg caaagaatac ggtcagaata 2989561 tgtagaaaag ggccaatatt ataaatttct tcaacaaaca taagacctgc ttcgtcttac 2989621 tttaccattt ttcaaattat atttgaaagc aataaccatc gttaacccgg acgtcataca 2989681 gttcgggttt cgatttttcc ataaaacgtt cacatatagc atgaaacgta tgacttttat 2989741 cttatcacaa aactataaac agcctctgca aaaacacata cctattcttt cctgttctct 2989801 attttctatg agcacacaca aaaagagccc actgggagct ctttttgtca gctgatattt 2989861 cgttcgctgg cagcagccgc atttttttta tgaaaccctt ttccatagta cacagccagc 2989921 aagatgagaa accatatcgg cccgataatc acggctactc ttgtatcagg gctgtaagcc 2989981 ataagaatga cgacgaatgc tagaaatgcc aatgacacat aagacgtaaa cggaaataaa 2990041 ggcattttgt actttaattg tttcttttct tccggcttca aacttttcct gtattttatt 2990101 tgagaaagca aaatgattgc ccacgtccaa atcgctccga acgtcgcaat acttgtaacc 2990161 caagtaaata ccttcgcagg gacaacatag tttaacagca ctccgactaa taaagcgccc 2990221 gctgaagcca gaacagcttt acccgggatg ccgcctttcg tcagctgacc atatgcttgt 2990281 ggcgcctctt tctgttccgc caagttaaac agcatccgcc ctgtgctgaa aataccactg 2990341 ttgcatgaag acagcgcggc tgtcaacacg acaaagttaa tgatacctgc ggccgatgga 2990401 atgcccactt tttgaaatgt gagaacaaat ggacttcctt gagagccaat ttcctgccac 2990461 ggataaatag acataatgac aaataaagcg cctacataaa aaatcaaaat ccgccaaaat 2990521 actgtatcga ttgctttggc taacgatttt tgcgggtttt ttacttcgcc agccgtcacc 2990581 ccgatcattt caatccctaa ataggcgaac atgaccattt gaagagacaa taaaacccct 2990641 tttaatccat gagggaaaaa tcctccgttg ttccacaaat tgctgattcc ggttgcaatg 2990701 cccccattgc cgactcctgc aataatcatc aataaaccga cagcaatcat ggataagatt 2990761 gcaacaattt taatcaatgc gaaccaaaat tccagctcgc cgtaagcttt gacagccagg 2990821 aaattaacac ccgtcataat gaccagtgcc gataacgccc aaatccagtt tggcacgtcc 2990881 ggaaaccaga accccatata gatgccgaca gcagtgattt cggccataca ggtgacaacc 2990941 cataaaaacc agtagttcca acctgttaaa tagcctgcaa gcggtcccaa ataatcacgc 2991001 gcatacctgc tgaaggagcc tgcgaccggt ttttgaatgg ccatttcccc aagcgctctc 2991061 ataataaaaa acatgaccag gccgcttgcg gcatacgcta ccaaaatacc aggccctgct 2991121 aattgaatag ctgatgcgga gccgaggaac aaccctactc ctatagcagc tcctaaagac 2991181 attaaagaaa tatgcctttc ttcgagtccg cggtgcagct cttgtttttg tttttgcatg 2991241 cttcttctcc cctagaaaaa aatatcatta tatcattttt ctgaatattc cgtacggatt 2991301 gggtaaatca atgatgatgg agaaataaaa ggataacaac aaggctttcg actactcgaa 2991361 agccttgttg tctgttacac aaagatgact tctttaggct gatggctcag ctcttcaggc 2991421 atataccgtt tttcaatatt gatgctgtgc cagatcataa agattagcac agtccaaatt 2991481 ttacggctgt tatcagcctt gtccgcacaa tggtcttcaa gaagctgaag gacataatcc 2991541 ttatggatat aagcatccgt ttggctttct tgaataatat tccgcaccca ttcgttcatt 2991601 tcgtttttca gccaatgacg gatcggtaca gggaaaccaa gctttttgcg gtttaatacg 2991661 tgctcaggca caattccttc agcggctttg cgaagaagat acttcgtcgt gccgttcttc 2991721 gttttcagct catcaggaat ttttgaagcg acgtcgaata cgactttatc caagaacggc 2991781 acacgcagtt ccaaagaatt cgccatcgtc attttatccg cctttaacaa aatgtcgccg 2991841 cgcatccaag tgtggatatc gacatactgc attttgttga tatcgctgta cgagctgctt 2991901 tctgtaaagt aagtcttcgt cacatcgcga tatgaaaggt tcggattata atgcttcaac 2991961 agctgctttt tgacagactc ttcaaagatt ttcgcgttac cgatataacg atcctgaagc 2992021 ggagtgcagc cgcgctcaag caggctcttc cctctcatac cttcaggcat aacggcagca 2992081 acgtgcagaa gcatcttttt caagccggac ggaatccgtt caaacggttt aagcgaaagc 2992141 ggttcacggt aaatgttata tccgccgaag agctcatccg ctccttcacc tgataaagca 2992201 accgtaacat gtttttttgc ttcttttgca acaaagtaca acggaatcgc tgccggatca 2992261 gcaagcgggt catcaaaatg ccatacgatc ttcggaagct cattcatgta ttcctcaggc 2992321 gaaatgactt tgctgatatt ttcaatgccc agcgccgctg ccgtttcttt cgctacatca 2992381 acctcactga agccctgctg ttcaaagccg acagagaatg tttttaagct tggatgaaat 2992441 tccttcgcaa cagacacaat aaaggaagaa tcaatcccgc cagacaggaa cgaaccgaca 2992501 ggaacgtcac ttctcatatg aacgtttaca gagtcataga tcgcgtctcg gacttctttc 2992561 acaagcttgt cttcttcagt ctgaaccggc ttgaagttcg ctttgaaata cgttttgaat 2992621 gtgatatcgc cgtccgggcg gattgtgaat tgtgaacccg gctctacttt tttcacatgg 2992681 gcatcaagcg tgcttggttc aggaacaaat tggaaagaca tgtactgctg caatgcctct 2992741 ttatctattt caatatcatt ctgagcaacc attaaacttt ttctctctga ggcaaaataa 2992801 acctgatcat tgatcgttgt gtagtacaac ggtttaatgc cgaatggatc tcttgcccca 2992861 taaagcacat gatcgttttt attccaaatc agaaaggcaa acataccgcg cagtttggac 2992921 gccgcttctt ctttatagtg acggtaagtc gcaagaagaa cctctgtgtc cgaatccgtg 2992981 ttgaatgtgt acccctttgc ttcaagttct tctctcagtt cgatatagtt atagatttct 2993041 ccgttaaaga taatccaata tgtttcatct tcatatgata aaggctgtcc accattttct 2993101 acatcaataa tgctgagccg tctgaatccg aagccgacgt gctcatcatg gaaatatcca 2993161 tcactgtcag gaccgcggtg aacgatcatt tggttcattt gtttgattag ttcttcttga 2993221 tcagcggttt gagctaacgg atgcttgtta aaaaccccga caaatccaca catagtattg 2993281 cctccataat taaaattgtc atcattgaac ccctatttat agacgctgtg aatagtattt 2993341 ggtttcacag ttatgtaaaa aaataaacat gaatacaacg ataaaaaagg gaaagccgct 2993401 taaccagtaa gcggctataa aattattctc ctaacgcttc tttacgcagc tgctccgctt 2993461 tgtctgtgcg ctcccatgga aggtcaacat cgtgacgtcc aaagtggccg tacgcagcag 2993521 tttgtttata gatcggacgg cgcaaatcaa gcattttgat aatgccggca ggtcgtaaat 2993581 caaagttatt gcgaacaact tcaatcagtt tttcctcaga agcttttcct gaaccgaatg 2993641 tgttgattga gattgacaca ggctgtgcaa caccgatcgc gtaagcaagc tgtacttcgc 2993701 aagaatcagc aagctcagcc gcaacgatgt ttttcgcaac gtatcttgcc gcataagctg 2993761 cagaacggtc taccttcgtc gcgtccttac ctgagaacgc gcctccgccg tggcgtgcat 2993821 agccgccgta cgtatcaacg atgattttgc gtcctgtaag tcccgcatcc ccttgagggc 2993881 ctccgattac gaaacgtcct gtagggttga tgaaatattt tgtttcttca tcaatcagct 2993941 cttcaggaac aaccggattg attacatgtt ctttaatgtt gcgctgaatt tgctcaagtg 2994001 taatttcagg gtgatgctga gttgaaataa caatcgcgtc aatgcggact ggtttgttat 2994061 tttcatcgta ctcaaccgtt acctgtgttt tgccgtcagg gcgaaggtac ggaagaatat 2994121 cttctttacg gacttcactt aggcggcggg ctaatttatg ggcaagtgaa attggaagag 2994181 gcataagctc tttcgtttcg ttgcacgcat aaccgaacat taatccttgg tcacccgcac 2994241 caatcgcttc aatttcttcg tcgctcattg tgccttcacg ggcttcaagc gcttggtcta 2994301 cgcccatcgc gatatcagca gactgctcat caattgatgt taaaaccgca caagtttccg 2994361 catcaaatcc gtattttgca cgtgtgtatc cgatttcttt aatggtttgg cgaaccgttt 2994421 tcggaatgtc aacatacgta gaagttgtga tctctccgct tacaagaacc aaacctgttg 2994481 tcacagatgt ttcacaagca acacgcgcgt tagggtcttt ctttaaaatt tcatctaaaa 2994541 tgctgtcaga aatctggtca cagattttat ccggatgccc ctccgtaaca gattctgatg 2994601 taaataaacg acgattttta ctcatgattt gcttcctcct gcacaaggcc tcccgaaaga 2994661 ccttgtatat atgatacgga actcgctccc tcttatacaa tgtacagtta tattagagaa 2994721 tgttaattgg catatttatg aaataaaaaa accttttcca tcgaggaaag ggtttggtct 2994781 ttgtgccttt cactcttatc gctcaaggaa tcatacaacc ttgcaacagg ttagcacctt 2994841 ggttgtctca ctcagttgaa cataataaat aacagagaaa ccggttgctg ggcttcatag 2994901 ggcctgtccc tccgccagct cgggataaga gtatccgctc aatgaaatat cttatcgtaa 2994961 aagggtttgc aatgtcaata tgattcagaa gaaataggca cctatattga gggaaaacaa 2995021 tggaaatgca cacacaaaaa acaataaata gtatagacta tttgaaaata tatgttatac 2995081 taattcacaa ttagcaaaac acaaaaaacg ataaaggaag gtttcatatg aactcagttg 2995141 atttgaccgc tgatttacaa gccttattaa catgtccaaa tgtgcgtcat aatttatcag 2995201 cagcacagct aacagaaaaa gtcctctccc gaaacgaagg cattttaaca tccacaggtg 2995261 ctgttcgcgc gacaacaggc gcttacacag gacgctcacc taaagataaa ttcatcgtgg 2995321 aggaagaaag cacgaaaaat aagatcgatt ggggcccggt gaatcagccg atttcagaag 2995381 aagcgtttga gcggctgtac acgaaagttg tcagctattt aaaggagcga gatgaactgt 2995441 ttgttttcga aggatttgcc ggagcagacg agaaatacag gctgccgatc actgtcgtaa 2995501 atgagttcgc atggcacaat ttatttgcgc ggcagctgtt tatccgtccg gaaggaaatg 2995561 ataagaaaac agttgagcag ccgttcacca ttctttctgc tccgcatttc aaagcggatc 2995621 caaaaacaga cggcactcat tccgaaacgt ttattattgt ctctttcgaa aagcggacaa 2995681 ttttaatcgg cggaactgag tatgccggtg aaatgaagaa gtccattttc tccattatga 2995741 atttcctgct gcctgaaaga gatattttat ctatgcactg ctccgccaat gtcggtgaaa 2995801 aaggcgatgt cgcccttttc ttcggactgt caggaacagg aaagaccacc ctgtcggcag 2995861 atgctgaccg caagctgatc ggtgacgatg aacatggctg gtctgataca ggcgtcttta 2995921 atattgaagg cggatgctac gctaagtgta ttcatttaag cgaggaaaag gagccgcaaa 2995981 tctttaacgc gatccgcttc gggtctgttc tcgaaaatgt cgttgtggat gaagatacac 2996041 gcgaagccaa ttatgatgat tccttctata ctgaaaacac gcgggcagct tacccgattc 2996101 atatgattaa taacatcgtg actccaagca tggccggcca tccgtcagcc attgtatttt 2996161 tgacggctga tgccttcgga gtcctgccgc cgatcagcaa actaacgaag gagcaggcga 2996221 tgtaccattt tttgagcggt tacacgagta agcttgccgg aaccgaacgt ggtgtcacgt 2996281 ctcctgaaac gacgttttct acatgcttcg gctcaccgtt cctgccgctt cctgctcacg 2996341 tctatgctga aatgctcggc aaaaagatcg atgaacacgg cgcagacgtt ttcttagtca 2996401 ataccggatg gaccgggggc ggctacggca caggcgaacg aatgaagctt tcttacacta 2996461 gagcaatggt caaagcagcg attgaaggca aattagagga tgctgaaatg ataactgacg 2996521 atattttcgg cctgcacatt ccggcccatg ttcctggcgt tcctgatcat atccttcagc 2996581 ctgaaaacac gtggaccaac aaggaagaat acaaagaaaa agcagtctac cttgcaaatg 2996641 aattcaaaga gaactttaaa aagttcgcac ataccgatgc catcgcccag gcaggcggcc 2996701 ctctcgtata aaaaacaaaa gccaagagca attatgctct tggcttgttt taattgacgg 2996761 aatgcaaaga agtcagcttg tatgtaatga tggtccggcc ttcttcccat tgaagcttct 2996821 gcacttcagc tgtgcctgac ttttcgccaa actttgtttt gcgtacatcc attggaatct 2996881 ccatcggata tactcggtat ccgtccttct ctaacgtgaa tatattttca tctatgcgaa 2996941 cttcttttcc ttttgtcaca atcagtgtat taaattcaac aggcattccc aaagtgaaat 2997001 cccctttcgt tctctttttt ctttatcata acatatttca ctgtcagcgg tttttcatcc 2997061 attgtgtgag ctgccgcacg atacgccggt tttcttttgg cgggaaataa tgtgtgaatg 2997121 tactgtagta ccatgtttcc accggcttat gcagttgttt tagcttctct tctaataaat 2997181 aggaatgctg aatcgaaaca ttttggtctt tttctccatg gattaacagc acgggagcct 2997241 gaattttgtt tacttggtca aacggtgtcc tccattgata ttcctcaggc acctttttcg 2997301 gtgttccgcc gatgactctt ttcatcattc gccgcaaatc ctgccgctcc tcgtatgtaa 2997361 gaatcatatc actgacgcct ccccaggaaa caaatgaagc tgcctgcccg cccatttcga 2997421 tcgcagtgag cattcccata attccgccgc gggaaaaacc gaagatatgg attctatcct 2997481 tcttgacatt tgggtgctgc tgaagcaggc gaaaagcaga aaatgcatcc tccctgtctt 2997541 ctccggcaaa atcctcattg ccttctcctc cttgattgcc tctgtaaaaa ggagcaaaca 2997601 ccacaaaccc ttgggatgca aactggataa tccggcccgg ccgaaccatg cccacgcttt 2997661 taatcccgcc gcgcaaatat aaaaatccgt catattgtcc cggttccgcc ggctcagcca 2997721 gaagcccctt aacccgtaat ccatttgaca gatagcagat cgtatacaaa cgcacatgct 2997781 ggcttggcga cggaaatctt cttttctcta caatcaaaac agccgcctcc ttttttctat 2997841 atgctttcct tactccaaaa ttacatccgg agaacctggt taggcattca cacattttta 2997901 tacccatcat acgatatgta aagcaaaaaa ggatattaac ttgatgcgaa ataaggaggt 2997961 tgtctatgtg aacagatggt taaggctggg cttcgcctgt gtcggcagta tctttctgat 2998021 gttcgccctg gcggcttgca agcaggaaga aacgctcacc aaagtcaaag tagctgaagt 2998081 gacccattca attttttacg cacctttata tgttgctgag tctaaaggtt tttttaagga 2998141 agaagggctt gatgtcgatg tgaatacgac ctggggcgga gataaaacga tgacatcgct 2998201 tctttccaac ggctccgaca tcgcgcttgt cgggtcagaa acatctattt atgtcgaagc 2998261 gcaaggggct aaagatcccg tcattaattt cgcccagctg actcagacag acggaacgtt 2998321 tcttgtcgcg agagaagatg ttgaacactt cgactgggat cagctgaaag gaaaaacgtt 2998381 tctcggtcag cgaaaaggcg gcatgccgca aatggtcggc gagtatgtac tgaacaaaca 2998441 taagattgac ccgcataagg atatagacct catccagaac atagacttcg ccaatattgc 2998501 caatgcgttt gcttctggaa ccggtgagta tgtacagctc tttgaaccgc aggcttctct 2998561 ctttgagaaa aaaggcatcg gccatatcgt ggcttcattc ggagaagaat caggagaggt 2998621 tccttatacg acttttatgg cgaaacaaag ctatttgaag aaaaatgaag acacagccgt 2998681 caagtttaca aaagccattt ataaggcgca gcagtgggtt gaaaatcatt ctgcgaagga 2998741 catcacagat gccattaaag atgaatttga tgataccgac ccagacgtca tcgaaacatc 2998801 cattgaacgc tataaaaaac agcattcata ttcaccagac cctctgctta acgaaaaaga 2998861 atgggagctt ctccaaacca ttatggataa atcgggagaa ctgccgaagc acattccata 2998921 caatcagctt gtaaataaag aaattgctga aaaagtcacc tcggagaaat aggaggcgcc 2998981 atctatgtct ttcttacatg tcgaccatgt aacccatact tatttttcta ttaaagaaaa 2999041 aacaacggct gtgcgggata ttcatttcga tgccgaaaaa ggcgatttca tctcatttct 2999101 cggcccaagc ggctgcggaa aaacaacatt gctttccatt attgccggtt tgattgagcc 2999161 atcagaaggc agagttctga ttgaaggccg tgagccgaat caaaaagaac ataatattgg 2999221 ctatatgctt cagcaggatt acttatttcc ctggaaatct atcgaggaaa atgtgcttct 2999281 cggtttaaaa atcgccgaca cgctgacaga agaaagcaaa gccgctgcac tcggtctatt 2999341 gccggagttc ggcctcatag atgtggagaa aaaatatccg aaagaactgt caggcgggat 2999401 gcgccagcgg gctgcgcttg caagaacact tgcgcctaac cctagtctgc ttttgctgga 2999461 tgagccattt tccgcgcttg attttcagac aaagctgtct ttggaaaacc tggtattccg 2999521 cacattaaag gaatatcaaa aaacagcagt gcttgtcact catgatatag gggaagcgat 2999581 agcgatgagc gatacgatct ttttattttc aaatcagccg ggcaccatcc atcagatttt 2999641 taccattcct aaggaattgg ccgcgatgtt gccttttgac gcccgtcagg aaccttcctt 2999701 ccagacactg tttcaaacga tatggaagga gctgaattct cttgagaaac agcaaagaaa 2999761 ccattgatct gcttcacgag cagtatcaat tcaaacagaa aaaggaaaag tggaaggtcc 2999821 attcctttca gcttgccata tttattctct ttttctcggg ctgggaaatc tccagcaggc 2999881 agggctggat cgatccgctg atcttcagct ctccatcagc tgtgtggcga ttattgctgg 2999941 agaaacttgg tgacggttct ttactgtcac acatcggcgt cactttattt gaaacggtgc 3000001 ttggcttttt gctcgggacg tttatgggca cgtgcctagc cgctttgtta tggtggtcta 3000061 accgacttgc cagaatttta gatccgtatc ttgtgatttt gaacgcaatg ccgaaagtgg 3000121 ccctgggccc gatcctgatt gtcgcgctcg gtcccagttt tatcagcatc attgcgatgg 3000181 gagccatcat cagcgtcatt atcacaacca tcgttgtcta caccgccttc caagaggtcg 3000241 acgaaaacta tacgaaagtc atgaaaacat tcggcgcaaa aaagtgggtt atttttaaag 3000301 aagtcatact gcctgcatcc tcccccgcga ttatttcaac actaaaagtg aacgtcggtt 3000361 tatcatgggt tggcgttatt gtaggggaat tcctcgtttc gaaggtcgga ttaggatata 3000421 tgattattta cggattccaa gtcttcaatt ttacactcgt cttcttaagc ctgctgatca 3000481 tcgccatctt cgccactctg atgtatcagg gcgtcgagct gctggaaaag aaatggacga 3000541 aggggaggac ataaaaaacc cggcacatgt gccgggtttt ttattcaatc catccagatt 3000601 ctttcagttt tttcaagctg atcggaagaa cggaatcctt cataataaag ctgaattttt 3000661 tattgcggga aaggttctcc ggcagctcgt gaaacaaaac cgggcctttc gtttcaaagt 3000721 aatcagcctg cttttcaagc ttttctatat ctgcaaaata tatatttttt acaatcactt 3000781 tttcttttcc gagaacttta tactgtccga gatacttgag gcttttgact ctcgcgcccg 3000841 tctcttcctt tacttcccgg agcgcagcct cttctgcgca ctccatcggc tctactttcc 3000901 cgcctggaaa ctcatagcct ctgtcctcat gttctgttaa aagccatttg ccgccaaaac 3000961 ggcaaatcac ccagacatgc ttcgggctgt ccgagaaagg ctgatcgtca aaggaaagct 3001021 gaacagtatt ctgataataa tctttaaact cgtacatgtt tatccctcaa atccgttcct 3001081 agctatcttc catacatcat accacagtta cgtttcttcg gaagcctttt atcaaaaaat 3001141 aagggaaacc cagcacgccg tcaggttctg catgcagact agctcgtaca gtttttttgc 3001201 gatacttttg ccggaaagtg cgaccgacgc tctgggcttt attatgaccc gcgaacaggg 3001261 aaaagttacg gtttgcgctt aaatttattt tttaacgttt ctaaaagatc gacaagcatc 3001321 tgaggaaccg gtatgccaag agagctggct gtcacaacaa tttgcacaga ttcataaaga 3001381 atataaaaca taatagccaa gtcacgaatt gatccctgtg tattcagcag ctgatcaaaa 3001441 aagtggcata cagagatcag agccagcgtg actaattttt tgacaagccg ggcaaatacc 3001501 tttttaaatg acagtttgtg aataatggtt tccttcaaag tcgtactgat aaattcaatt 3001561 gccataagag agagcaaaat cagaaatgaa tactgaaaac ctccaaagaa aaaacccgct 3001621 gctgaaacgc tgactgctaa aaacgaaaag atgccaaagt ctctatccat ttatcccaac 3001681 atcctttcac agaaacggcc ttacgatatt ctatggtaaa caagccgaac ggattggatt 3001741 tttcagaaaa atggactggt tgtcgcctat ttttcagata caaaaagaaa agccggacgt 3001801 cttttttaag acatccggcc gttctatttt tgaacttaac ctaggtaagc ttttagcatc 3001861 cagttatgtt tttcaatatt ttgatggatc gcaagaagca tgtcccctgt tgtttcgtca 3001921 ccgacttcat cagctaaatc catgccgttt ttcagctctt ccgcgatgac tgtgaaatca 3001981 tcatatacgc tttgaaccat ttgttcagct gtttcatttc cagcagcttc tttgacagaa 3002041 gccgtttcta aggattcctt cattgttgca atcggttttc cgttcagcgc caaaagacgt 3002101 tctgctaagt catcaatata agttgctgtt tcgttgtaca gctcctcaaa cttttcatga 3002161 agagtgaaga aatctttccc tttcacatac cagtgataat tatgtagttt cacatacatg 3002221 accgtccagt tggctacttg tttgttcact gcttgaatca attgttctga catggtatct 3002281 cctccttgtt atatgactat gtataccctt aatatcgtac gctaaaacct cttttttacc 3002341 cttatctgtc acgatttctt ctattatgct acaattgtta aaaaacggga ggtggaatgt 3002401 catgacgctt ctcattacga taagtatttt gattgtgctg gctgttttgc ttgtaaccat 3002461 ttggacgact gtaaaagcct ataatgtaaa gcataccatt gatccaccac aagaaaatca 3002521 ctctgattca cacaatcaat gatgatgtga atgctcctct tctgactgat tgctggcagc 3002581 atcggcgtct ccgacttgga cttttaaggt cggcatgcta tgctgttttt ttgctgtgac 3002641 atgagattgg acagtgtata caccatcttc cttaaacgtc gtttccaatc ggtatacgcc 3002701 tttttcttgt ttcaccttaa acatttggct tgcgtctttt tccccttctt tccatacttc 3002761 aaactctact tcatcggcat ccgtcacagc ttcatcacca tatgatacag ctgcttcata 3002821 agcagcgctt tctccgggat ttactttttc aggcccggtc agcttgacat ccaaaacctc 3002881 gggcgtctca gctgtatttg ctttactttc accagatccg catccattaa gcaataaagc 3002941 agaaaaaagc agaacaacca acatcttttt catgccatca ccctttcatc gtttacctaa 3003001 atagtagcaa acgcttacag caaatggtac acaaaatatg agacgtcaca aaaaagacct 3003061 ttttgcttaa gcgcaaaaag gtcctttcta ttttagccaa atacttttag caattcttct 3003121 ttatcctgtg aaagccagaa acgcattaaa cgtttagcgc cttccagatc atgaagcttc 3003181 gcttggccgc actgcttttc attcgcagca ggtatttctg taatctctac cgcttccttc 3003241 attgtgtctt caagcagatc aacgatttcc gctgatgtcg gctctccgct cacaactaga 3003301 taatagcctg tctggcagcc cattggagaa atatcaatga tatcaaaatg atcgtatttc 3003361 tcagcgtgag aacgaatcgt aaacgcgagc aaatgctcga gtgtgtgaat ggtgtcaggc 3003421 ttcatcgcct gtttatttgg ctggcaaaaa cgaatgtcaa atttatttac aacgccgtct 3003481 gttcccactt tatgcacgcc gcaatgtctt acatatggag caacaaccgc attatgatca 3003541 agctcaaaac tttctactga aggcataatg gcactctccc cttttttaaa aatgtaattt 3003601 cattataaca tacttttccg ataagaatta ttgattaact tttcaatctg tgtttttttt 3003661 cttatacttg catcagaaag gttgctgaag aaacatgaaa accctattca tcgctctgat 3003721 cagaggatat caaaaattca tctcgcccct gacaccgcca acgtgccgct tttatccgac 3003781 ctgttcccaa tatggaatcg aagcgattaa aacacatggc gctttaaaag gcggatggct 3003841 gacaatcaaa cggattttga aatgccaccc gttccatccg ggaggagtcg atcccgttcc 3003901 tgaaaagaaa caaaaacatt aattgttata accgtttacg ataagatcca gttttccggt 3003961 tttaggatca atgactaagc catggaccgg aacgttttca gggaacagcg ggtgatgttt 3004021 aataacatct acgctgtctt tcacactcgc ttccactgaa tcaaagcttt taaaccattg 3004081 atcaaagtct acaccggagt actttattgt ttcgatgcgt tcttccggaa tccctcttgc 3004141 tttgattttt tcaagcatgc ttttgctgct gattttgctc atgccgcaat cgtgatgccc 3004201 gatcacacac acctcatctg cattcagctc gtacactgcg acgagtatac ttctcatgat 3004261 gcttccgaat gggtgtgtca caagcgcacc ggcactttta atgattttca catcaccgtt 3004321 tcgcaaattc atcgcatgcg gcagcagttc aaccagacga gtatccatgc aagaaagaat 3004381 cgccattttt ttatctggaa attttgatgt ttgatacttt tcatactctc tttgttcagt 3004441 aaatgtcttg ttaaattcga gaatatcatt tagaagactc atgttcgttg tccctttcta 3004501 ttctttttac tcttcaatat atcacaaccc ttgtttattc gtcataataa aaaaagacaa 3004561 accctcaggc ctgccttatt tccccatgtt atagcgtttt ttgaactgct caactcgtcc 3004621 gcctttttca ttgaatttct ggcggcctgt ataaaacgga tgcgtgtcag agcttacctc 3004681 tactttaatg acaggatatg tgtttccgtc ctcccactct gctgtttcat tagatgtttt 3004741 cgtagaggtg cttagaaaac ggtagccgct gttgacatcc tgaaatatca ctttgtggtt 3004801 ctttggatga attccttctt tcatgggtat ctcctttcaa taaatcgtaa taattacgtt 3004861 ttattttata accttacaaa cgttttgtca atcttcttat atccttccct ctgtttcaca 3004921 tcgtaaacct catggcattt aagaatagga agaataatct aaccgaggaa gcaaataata 3004981 aacccaaaat acatacagaa cgtctttttg gaaaggtggt ttacgattgt ggatgattta 3005041 gttttggcca gaagcctttt tggcacgacg atgggctttc atatcatttt cgcaacactt 3005101 ggagtcggtc tgccgctcat gattttagtg gcggaattga tctatcaaaa aacgaaagat 3005161 gaccattatg cgatcatggc gaaaagatgg acgaaagcac aagccgtttt gctgggggtc 3005221 gccataccga ccggaacgat cgcgggcact cagctcgcgc ttttatggcc gggatttatg 3005281 gaagtcatcg gccgggtgat gtccctgcca tttcaaattg aaatctatgc tttttttgtt 3005341 gaagccctat tcatgtcgat ttatgtatac gctgcagacc gtttgtcacc tgcaatgagg 3005401 attgttgctg ttttctttgt gttagtcggg gcagcagcat ccgctgttct gatcacgaat 3005461 gttcacgctt ttgaaggtac gcccgccggt tttaaaattt taaacggaaa aattacagat 3005521 gttgacccgt gggctgcgtt ttttaatcct agctttttta tcactgccgg ccatgtcgtg 3005581 ctgtccgcgt ttatgactgg tgcgtttatc gtggcttctg ttgcggcgta taaaatgatc 3005641 cgaacgagga aaaaggaaag ggtctatcgc tttcaccgga aagccctttt gctcgcactg 3005701 acgatcggcg gtattttttc attgctgacc gctttgaacg gacacgaatc tgcacagatg 3005761 ctgtacgaat accagcccga aaaattagcc ggtgcggaag gcctatttga aacaagatcc 3005821 cacgccccgc tcgctatcgg cggttttacc gacccgaatg aagaaaaagt aaaatgggca 3005881 atcgagattc catgggcttt aagctttttg gcagcgaacc gttttgacac tgttgtaaaa 3005941 ggattaaatg catttccgag agatgaatgg ccgccgcttt tcattcacac gctgtttaat 3006001 gcgatggttg gtgtaggcat gctgctaatt ctttattcca ttatcggtgt ggtctggaga 3006061 aaggtgctca agaaagaccg tttcccaacg tggcttttga tcattttcat gacagcaggc 3006121 ccttttagtc tcatcggcat tgaattcggc tggattttcg catgtacggg gaggcagcct 3006181 tgggtcatct atcatctgct gaaaacgtca gatgtcgtaa caacgactgg ctcgatcggg 3006241 gtgctgttct tatttttcac atttgtttat gccgtgttag gcgcagctgt cgtctacgtg 3006301 ctgctgtatt atttccgcaa gcacccggtt gacgaagatt taaatacagc ggagtcgtaa 3006361 tggctccgca aacaggaaac caaatggaag gaagatcgta caaatggaga tttcaactga 3006421 cgctctgatc gccatctcaa ttatctgggg ctttgtgttt atttacgccg tcatggcgac 3006481 aatggatttt ggagcgggat tttggtctat gatctattta aacaaggagc atatgaaggc 3006541 caccgatatt gcgaatcgct ttttgtcccc gacttgggag gtcacaaacg tctttattgt 3006601 ggccatcgtc gtggcgcttt tcagtttttt ccccggcgcg acatttgtgc tcggcaccgt 3006661 tttattaatt cccggaagca tgattttgct gcttttagca attcgaagcg gatttctcgt 3006721 gttttcaaat acagcaaagg agcggaaaac gctaagatat atttccggca tctccggctt 3006781 tatcattcct gctattttaa ttttggtgct tcctgtgaca cacggagggt ttatagaaaa 3006841 aacggatgga atctataact taaatatgtc taaaatcttt tcaagcccca acgcctattc 3006901 atttatcggg tttgcgattt taagcacctt atttttgtcc tcgctgttgc ttgcagattt 3006961 ttcaaatgtg gcagaggaac aggatgcgta ccgagcctac agaaaaagcg ccctgattac 3007021 cggcccgatt tcactgttgt ttgctgtatg cattatggta actatgcgga atgaagcaaa 3007081 ctggctgtac agcggaatga tgaatgattt ttcttggatt attgcatcgt tcattacatt 3007141 tgtcattgct ggaatcgctc tttttctgcc taacaaaagc tttggtcaaa acatcggaaa 3007201 accgcgtctc gcacttgttg cgattgggat acagtatttt ctcgcaagct acgcgtacgg 3007261 gcgggcgcat cttccgtata tgatttatcc cgatgtgaca gtcatgtcag gcttcacaga 3007321 gccagcaacg ttcagagcgc tgtttgcaac gtatatcgtt gcatttatca ttctatttcc 3007381 gggcttcttt ttcttctgga aaatgtttat gcgagataaa cgctatatcc gccaggagga 3007441 atagagggca agccagccgg ctatactaat ccagaacctt tataaggagg ggatggcatg 3007501 gagcagaaaa ttctatgtga ggtcaacaac tgttcttatt ggggcaaagg taacaaatgc 3007561 accgctgatg ccatttatgt tgtcagccat actggtgaaa cggctgaaaa cagccgggaa 3007621 acagactgca aaacgtttaa gccgcatgat ttataattaa aagaaagagc tgcatcagcc 3007681 agctctttct ttttgcatgt tgagtgttct cagcttttta gttatgaccc cgtttgcagg 3007741 tgaaaacaaa aaggcgcttg cataacatac acctgtcatg gccgccatcg ctcctgaaat 3007801 cgaaacatta agccacgttg cgaagaaata gcccatgacc gccgacagcc cgccaatcaa 3007861 cgcgctgaga atcagcatat aaagaagccg gtctgtcagc aaatgtgccg cagccggcgg 3007921 aacaatcagc atggccacaa ccaatacggc acccaccgaa tcaaaggaag caacagtcgt 3007981 caaggacagc atgcccattt gcacgtaatg aatgagcaaa accggtattc ccaaggctaa 3008041 agccatttga ggatcaaacg aagcgatttt aaactcctta tagcacacac tgatcaacac 3008101 tacgtttaaa accagaacag atgccagcat ccaaaacgct ttcggcccaa tatcaacccc 3008161 gaataccgtc accgtattcc acggcacaaa agcgatttct cccattaacg agtgctcaat 3008221 atcgagatgg acattcgctc catacacaga aagcaaaata accccgattg caaataagga 3008281 tgtaaacaca actcctatgg cagcatctga ttgaaccccc ttgctatgaa gaagctgaac 3008341 caagaaagcc gttaacagac cggttgcggc tgcgccaata aacatataaa tcccatcgag 3008401 acttcccgtc actagaaaag cgccgacaat gccaagcaac actgtgtgac tgattgcgtc 3008461 ggccagcatc gccatgcttc tcagcacaag aaatgtgccg atcaatccgc agcttacacc 3008521 gactaataca ccggtagcta taatccatgc ttcaaaactc atttgcgatc tgtcccttct 3008581 cggcatcatg agacgctttt cgacgctcag gcatccgtcc atacagcttt aagagtgaat 3008641 aaagccgctc tctcgtttct ctcggtaaac ggtccgggtc aaagtagtcc tgatcggatt 3008701 ctatattggc aagttccatt tcatgcatga gatacacttc atacatccgc tgcttcaaag 3008761 ctgtgtgata gcctttttct atccctttgc ttgtgatttg ccaaatccca ttttcgatac 3008821 gctcaatgca cctctcttgt tccaagtcat ttaatgcctt aaggcataat gaaggggata 3008881 ggcgtctttt ctttcttaca ctttcaacag ttacacaaag attattcttt tcatactgtt 3008941 cataaatcgc caaaagcact tgctccctgc ttgttctgcg ccgcagcctc atcagcctta 3009001 tggctttagc agccaatccc cgcttaggcg cgcaaatcat tgaaaaaaga aagagcagcg 3009061 ttgcagataa gatcattaat ggccctgtcg ccattccctt catcgtggtg ctaagcaggg 3009121 ttccggccac tccgctgacc ccgcctgtaa tcccggcaat gatgatcatc ccggttaatc 3009181 gttcggtcca atatctcgcg gttatggcag gtgtaatcag catagccgcc attaatatca 3009241 caccaacagt ctgaagccca atgacgacag cacagacaat cagacaagcc aaaagcccgt 3009301 ttaaaaaacg caccgggatt cctaatccct ttgcaaacgc gagatcaaaa gtaatcaatg 3009361 taaattcctt aaagaaaaca atacatagga gcagtagaac agcggatatc cctgcaataa 3009421 ggatgatatc ctgcctgacc aatgaagcag cctggccgaa taaaaaagaa tcaagcccgc 3009481 tttggcttcc cgccccctgt tgctgaatat atgtcagcag aatgatcccg acgccaaaaa 3009541 acacagaaag aacaatcccg atcgccgagt cctcctttgt ttttgaaagc cgaggaatca 3009601 gctgaataca aaacgttccg agcagtccgg cgagcgctgc ccccagcaaa aagaaaggca 3009661 gtgatttttg cccggtgaac agaaaagcga gacacactcc cggcagagct gaatgggcca 3009721 tcgcatcgcc gattaaactt tgctttctca gcagcacaaa gctgcccaaa acaccgcttg 3009781 ccgtcccgag caaaagcgta ccggccagca cccactgtgt attcggatgc tgaagctgca 3009841 gccacaaact ttcaaacatt gcgctcactc cttatgtcct tctgccagca ctttatcttt 3009901 taaaaacgta agccttcctc catatgtttt ttgcaggttt tcgatcgtaa aaacgttttc 3009961 cgtcggtccg aaagcgattt tccttaaatg aagcagtaag atccaatcga aataatcctc 3010021 ggcggtctgc agatcatgat ggacgacaag cacggttttt cctttttctt tgagttctgc 3010081 caacagcgtc ataatcgcgc gctccgtcgc tgcatcaaca cctgcaaacg gttcatccat 3010141 aaaataaatg tcagcgttct ggcagagtgc ccgggcaaga aacacccgct gctgctgtcc 3010201 gcctgacagc tggctgattt gccttttcgc ataatcatgc atcccgactt ttgttaatgc 3010261 ggccttcgcc atctccacat ccgctttctt tggcctcttt aataaaccga ttctcccgta 3010321 tcttcccatt aggacgacat cgagcgggct tgtggggaaa tcccagtcaa ccgagccgcg 3010381 ctgcggaaca tatccgattc tggtccgctg atccttatag tctttgccgt aaatagagat 3010441 gtctccggaa gctctgggca caagaccgag aatcgttttg atcaaggttg attttcccgc 3010501 gccgtttggg ccgataatgc caataagttt tccttcaggc acctgcagcg aaatgtcctg 3010561 cagtacaggc tttttatgat aagcaaccgt cacattatca agctcaacag ggaacatatc 3010621 ctccacctct tttctttatt taagcgcttt agtaatcgtg ttgatattgt ggcggaacat 3010681 tccttcgtat gtgccttctt ttgtgccctt ttcacccatg gcatccgaat aaagctgacc 3010741 gccgattgtg actgtatggc ctttttcttt agcgccttcc accactgcat tgattgattt 3010801 ttcagataca ctgctttcta cgaacacagc ttttatttgt ttttctgtca gaagatcaac 3010861 cagctcctga acatccctta atccatagtc cgaatctgtg ctgagtccct gcaggccttt 3010921 taccttaaat ccatactcat tcccaaagta cgcaaacgca tcatgagcag tcacaagcac 3010981 acggcttttc tccggaatat gtgcgatctc cttacgcgac cacttatcta aatattgcaa 3011041 atcttctttg tactctttgg catttttccg aaaggcatct gcgtgctgag gcattgcttt 3011101 gctgaattgc gcttcaattt catccaccgc atagatccat aacggaatgc tgaaccagac 3011161 gtggggatca aacgtcttgc cttcccccgc gggaataagc ttatttttcg gaatggcctc 3011221 agctactgcc gccgattgtt tttgttcgcc gattttttgg aggacatcct ccattttccc 3011281 ttccaaatgc aacccgctgt acagaacaac atcggcagac attaattttt tcgtgtcacc 3011341 ttgggaagct ttgtaaaggt gcggatcaac ccccggtccc attaaagagg tgacttttac 3011401 gtgcttacct ccgatgtttt ctgctgcatc ggcaatttga gatgttgtcg ctgtcacttg 3011461 taattgctga tcagcgcttt ttccggctga atccgttccg catcccgtta aagcaaaggt 3011521 cgcaaaaagt actgctgcca tcagcccttg tctcatattt ctcctcctct ttgccatcaa 3011581 tgtccgattg ttttatctta tgttgtcagt tcttagacat gtgacattaa attagccaaa 3011641 agcatgtttt atttacacag gacaaaaagt ttccctcatg caaaattatc gcgtttggcc 3011701 atttttgtca agctgattta cataaaaaaa ccggctgggt cagcagccgg tccaaacgag 3011761 aagggatgta ttcaacgaac acttttactg taacagcaca gtgtcattta ttcaaaatag 3011821 caaaatgctt ttttcttaac catgctgtgt gaaaacatcc attttggtca catattttcg 3011881 cataatatct tggtttacct caacccctaa accaggctgt tttgacacag aaataaatcc 3011941 attatcaata cgaatatcag gagttacaat atcttcatcc caatagcgtg aggatgaaga 3012001 tatatcgcca ggtattgtga attgaggcag tgaagcaagc gccacgttct gcgctcttga 3012061 tatgcctgtt tccagcattc ctccgcacca aacctgcata tgatgctctt tgcataaatc 3012121 atgaattttt aaggcttctg ttaagccgcc gacacgagaa ggttttatat taataatttt 3012181 gcagcttcct agctcaatcg cccgtctcgc atcatcaact gaacaaatgc tctcatcaag 3012241 gcaaatggcc gttttcaaat gtttctgcaa gtggcggtgg tcaacgatat cgtcagcttg 3012301 gagcggctgc tcaatcatca ttaaatgata gtcatcaagc tcctttaaac ggctgatatc 3012361 cttcagttcg taagaggaat tggcatcggc cataagcggg atggttggga atcggctgcg 3012421 gatggccttg accaattcca catcctgccc aggctgaatt ttaattttta ttctttgata 3012481 accttctttt tgatagctct caatttcctt cagcatatcg tcaagaggcg ccaggccgac 3012541 taccaccccg gcagggactt tatctcttgt tccgcccaat gcctcagcaa gggatacgcc 3012601 cttctttttg gcataaatat cccatacagc cgattcaagt cccgcttttg ccatccggtt 3012661 tcctttatac cgcgccaggc tgtccggcac ttctgaaggg tgattgaatt cacggccgac 3012721 gacatttggg ataaaaaaat cttttagcat atgcaaacat gttccaatgg tttcctcggt 3012781 gtaccaaggc gaagagaaag cggaaacttc tccccagcct gtgacacctg atgtatcaat 3012841 ggcttccacg atcagaaatt tacgctcttg aagcgtttcg atactgtttt taaacggttt 3012901 ctttaagttc atgctcaaat ggtaaagcgt gattttttct atttcgatca tagcagttct 3012961 cctttacgcg catccttcag ctgatttcgc aagagcttat tagacgcatt gcgcggcagg 3013021 cggtcaagca caaagaattt tgccggaatt ttatacttcg ccaagcgttc tttgcagtag 3013081 tcagtcaatt ctcctgcgct cacaggcttg tgaaggacaa gataggcgtg aggcactttc 3013141 ccccattttt tgtcctcagc ccctgaaacc ccggcttcgg ccacagcggg gtgtgaaagc 3013201 agcactgact ccacttcggc cggataaatg ttttctccgc cggatatgat cagatctgaa 3013261 cgtctgtcta atacatataa aaagccttca ttgtccaaat aaccaagatc acctgttttc 3013321 agccagccat tttgaaagga ggcttcgttt gcgctctccc ggttaaaata gcttttcatg 3013381 acattcgggc ctttgaccat gatttcaccg tgttcatacg gttcacatac ctgtccgtcc 3013441 cgctctattt tgatttcaca cgaaaacagc ggtttccccg cagatccgag cttttccatg 3013501 ctgaattccg gcgacagggt aacaatttgc gagcatgttt ctgtcattcc atatgactga 3013561 aagacaggga atcctttctc acggcattcc tcaagcaatg gcagcggtgc aggaccgccg 3013621 ccgagaagaa tgcatctgat ggattcaggg cagcggtttg tttcttccaa aagactggcc 3013681 agcatagtct gcaccgcaga tatcattgtc acttcatgcc tgttgataga atgcagcaca 3013741 tcgcttacgg aaaaacgctg gtgaagcacg acagtcattc catagatcac agatttaaat 3013801 aatgcggaca atccgctgat atgaaagagc ggcaatgcga taagccagcg gtcttgttct 3013861 gttataccca aattaagagc ggacgacacc gcactgaaat aatggtttcc gaacgtttgc 3013921 tgaactccct tgggctttcc tgtcgtaccc gacgtataca tcagcgttgc cgttgcatcc 3013981 atttgcatat aagcctcgat ctcaatttcc tctgctgctt ctttcatcag ttcatccaca 3014041 tcaatcgttt gaacgatgtg ttcatattct ttcttctcaa agcttgaatc tgtcaataaa 3014101 aagccggatc ccgaatcctc cagctgaaac agcctttcat gtgttgacag cttcgtattc 3014161 aaaagcaccg ccttaacacc aagcaaaaaa caagcgtgaa cagcgtatac catttctgca 3014221 cggttttgga gcaaaatagc tgcagtatcc cctttccgaa ccgaatgagc ggcaagctgt 3014281 tccgccattc gtttagacgc ggcaaacaat tctgcaaatg tcacggtttg gtcttcatag 3014341 atgagagcga ttctctcagg tgtcagctgt gcccgctgca tgagccagtt gggctgttct 3014401 gtcagcatgt catcatctcc gaggtaaaat gtctgtattg aaaagaaaac agcttggacc 3014461 gcaaagtctc aagctgttgg tttactagat attgctgatc acggaaaacg agggaactgt 3014521 ccgaaatcag gtttgcgttt ttccttaaag gaatcacggc cttcttttgc ttcatctgtt 3014581 gtgtagtaaa gaagggtagc atcccctgca aactgctgaa ttccagcaag tccgtctgtg 3014641 tccgcgttaa acgcagcttt aagaaagcgc agtgcggtcg ggcttttttc aagcatttct 3014701 tcacaccatt taatcgtttc ttcttcaagc tgttccaaag gaacgactgt gttgacaaga 3014761 cccatgtcca gtgcttcctg tgcgttgtac tgacggcata ggtaccagat ttcacgtgct 3014821 tttttatgtc ctacaattcg agccaggtag ccagaaccgt aacctgcatc gaagcttccc 3014881 actttagggc ctgtttgtcc aaaaattgcg ttgtccgcag caattgtcaa gtcacatacg 3014941 atgtgaagca catggcctcc gccgatcgca tatccggaca ccatcgcaac aaccggtttc 3015001 gggatgacgc ggattaaacg ctgaagatcc aatacgttaa gacgagggat ctggtcgtct 3015061 cctacatatc caccgtggcc gcgcactttt tggtctccgc cagaacaaaa tgctttgtcc 3015121 cctgcaccgg caagcacgat aaccccaacg ttttggtcgt ctcttgcgtc agcaaacgca 3015181 tcaatcattt cagcaaccgt tttaggggta aacgcattat gtacctcagg tcggttgatt 3015241 gttatttttg caatgccatt atacgtttca tacaatatct catcgtatgt ccgttttgtt 3015301 ttccattcag ccatatgatg acctcctttt attctctatg tgaatgagtc agatgcttgt 3015361 caaaaactca ctcactattt taccaaacaa tcgcggctgc tccacatgga ccgtatgtcc 3015421 tgcttttgga acaatctcta ttctactaga aggaagcatc ttatgcacct cttgattgat 3015481 ggcgcaaaat ttttcgtccc actccccgca gatcagaagc acaggaacat ctatttcctc 3015541 tacacggctc cacaaggaag gctgtgaacc ggtgcccatg ccggttaaac tgttcgcaag 3015601 cccaatctta ttgttccgca gacggcccga tcgtatcctg taccgaatat cttcagccag 3015661 cctctgctga gatgaaaaca aagggatatt ctcccaatac gcaacaaacg cttcgagccc 3015721 gtctcgtaaa ataaaatcag caagcttccg gtcccgcatg attcgttccc gccgttcccc 3015781 aagtgttttg agccccggcg tcgtgctttc aagcacaagt gccgataccc gctcgggata 3015841 tgtcatcgca aaagagtaag caagccttcc tcccatagaa tacccaatca atttcacttt 3015901 gtgaagtttt aattgatcaa aaatctcggc aaggtcagaa acttgccggg ttgtgctgta 3015961 tcttttccca ttcagcgggg catcggtttc cccatgccct aaacaatcaa ttttgatcaa 3016021 acgggaatca ggcagcattt catcaagaaa agtccatgat tgtttgctgc cggtaaaccc 3016081 atgcagacag acgacggctt cggaagcatt cggtccctcg tctgccactg catatcggac 3016141 accatctgat accgttatgt ttacagttcc cattgttttt tcacttcccg cacagcctca 3016201 ttcagcatat cgcgatgaag ctggactctt gattggcgat ccgttttgat ttcaatcaaa 3016261 tggagtccgg gcttgtctgc ctgcggcgcg taagctgttt tgaattcatc ccaagaagcc 3016321 gggcatgaat acgttccgcc gtaaagtgca gccgcatgct tgaaatcgag ccctgtcggt 3016381 gtgccgaaca aatcttcaaa gtgtgtcttc tcagaagcct gcggcaaaaa ggagaaaatc 3016441 cctcctccgt cattattgac aagaatcaca gtaagaggaa tacccagctt tttggccgcc 3016501 agcaggccgt ttaaatcatg ataaaaagat aaatctccaa tcacaagggt aacaggcgct 3016561 tttgttcctt cacatacccc catggcagag gagacgacac cgtctatccc gtttgctccc 3016621 cggtttgaat aaatccggaa agggcggtcc tgcttttcaa aaaacgtatc aacatccctg 3016681 atcggcatgc tgtttcccac aaacagcgag ctgttttcag gcacaagatg ctgaaggatt 3016741 cgatagagat tgccttcaaa cgaaacatct tcactgctga ttgtttgcag atgctcgcgg 3016801 aaccgcccat tgacaaactg ccacttttcc agccactctg aggatctggt ggcagcagta 3016861 aggcctgcca tgatctcctc agcaaaaaca gacgcattac aatgaatcat atgcgcgctt 3016921 gcctgtgtcg ggtctctcca ccctccatcc tcgtcaatca cgatttgctg aatcgtcgga 3016981 tcatccttaa gccataagaa aaccggtttt gaaacaggca tcggtccaaa ccgaatgaca 3017041 acatcaggac ggagtttccg cttcagctca tcatctttta aaaacgaatc atacgcatca 3017101 ataacagtgc ttttatcatg aacaccattc cgcagattag acagcggatc tgctaaaatt 3017161 ggatactgaa gcgcttttga cagcgcaata atgttttcct tgtccgcatc actatggagc 3017221 tctccgcaga cgatcattcc tttttcagcc tctgcgagca tctcagccac atcagacagg 3017281 gactctcggt caacagactg cgtacccgtt ttcacagaca catgacggcc tgttctcatt 3017341 cttccaaacg gctcatctga aagatccggc atcagcggtt cgcgcagcgg cacattcaca 3017401 tggacaggcc ccatcgggcg cttttgtgct tctccggcag cgcggcttgc cagcgttcgg 3017461 atgtatctca gcatttgcgg agactcttca ggaagagcag agtctgtgaa aaacttaaca 3017521 aagttaccga ataagaagtg ctgattaata gcctgcggtg cgcctacttc gcgcagctca 3017581 tgaggccgat cagcagttaa cacaataata ggcacccttg aataatgggc ttcaaccaca 3017641 gccggataaa agttggccgc ggctgttcca gatgtacaga tcaatagtac gggacgctgc 3017701 ttcgcttttg ccaaacctaa tgcaaaaaat ccggcagacc tttcatcaat ttggacatgg 3017761 acgctgatat cgggatgcgc agcacaaaga acagccagcg gtgtagatct tgagcccgga 3017821 caaacgacgg cgtccgtaat tccggaaagg gcgaattcat caataaaact tccgatgtaa 3017881 tgagtaatcg ggttgactgt caacgcctct cacctcctaa tgcagagatc atcggcttca 3017941 atttaatctg tgtttcttca tattccgaga ttggttccga gtcttccaca ataccgcacc 3018001 cggcaaacag ccttgctgtg cttccttcga tgagccctga acgaatggcg accgcgaatt 3018061 ccccgttatc ctggctgtca atccagccga taggggccgc ataccagccg cgggacatcg 3018121 gttcaatctc cctgatcacg tcaacagctt tttcctgagg tgatccccca agcgcgggag 3018181 tggggtgcag cttctcaatt aagtcaaaaa tcgaagcaga ctcgcgcagc tgtccgacaa 3018241 tcggcgtaaa caggtgctga acgctttttg ttttgtacaa aacaggtcca tcaggctttt 3018301 caacctctga acagcttgat acaaaagcat tatgaatcat acctaccaca atatcatgct 3018361 caagcaggtt tttctcatcg tttaataatt caaggcctat ccggcggtcg tcttcttcat 3018421 tcacgcctcg tttaatggag cctgccagac aggaagacat gacagtgccg ccgtctcttt 3018481 tgatcagtct ttccggagac gcgccgacaa aggttttgcc ttcttgttca attgcaaaaa 3018541 catagcttgt ctgctgatcg tccagaagcg ttttaagcac cggttcaatt tggattggac 3018601 cgtcaaacgt gagcagcagc tctcgggcaa gaacaacctt atcatattgt ttctctttaa 3018661 tttggcttgt ggccgtttcg attgctttca gccaatcatc cttatccagc tcttcggctg 3018721 ctgcaatcac agcctgatct tcttgcttga aatcgggaac cataaattcc gccgcaaaag 3018781 cttttaagcc ttctaaaaca gcttctgcgt cttctcctcc gcttacccat ctgttaactg 3018841 ttaagaacgg gccttcagca gtcatcgtca gcataagcgc aggcacaaag aaatcccctt 3018901 ccgagaaatg gtcccattgt gaacctcttt cttcgcaagg gtcaaaagaa aatcctccga 3018961 ataacacagg tcccactgca gaatgctgca gcttttcttc ttcataaata tgaaaagccg 3019021 tctttttaaa gcgctcccat tgttcaaaaa cctcacgata ccgctcgctg tttttttgat 3019081 ttgtctggaa aaccgcttct ttgccaagac cgactattgt caattcactt tcaggatctg 3019141 accaaaaaaa tcgattgcct gtatattttt ttgctccgta attgaaaaat gatagagggt 3019201 caagagactc gatttgtctc gaatagctta ttaagacagc atggttgact tctttggctt 3019261 tatgtaatgc atgtagaact tcctttcgga acgtacgctg caccgttgtc accatgagac 3019321 attcctccat aatccttaaa atgcttttaa taccatacac ctgtgtctcc tttgtgtcaa 3019381 acacagatca tgcagtccaa atggcctgcc ttacctatta taaacctaat ttcagaaatg 3019441 aaaaagaaac aaagcttaaa tttctttctc cactgatagc aaaggttgta tccgcttacc 3019501 ataaaaggaa aacctcctat attcctccac ccgccattta tgaaagttct caggcgatct 3019561 gttcatacta aaggtatgca tcacagagaa acgaggcgat cacattgctt acgaaagaac 3019621 agcttcagca tttaaaaaat gaactggaac aaacgaaaaa agatatctta aaccgtttca 3019681 aagacaatga tcattttcag cttaactcag cctttcctta tgattcgtgg ggtgagcttt 3019741 cggcatacga caaccatccc ggcgatcagg cgacagaact ttacgagcgt gagaaagaca 3019801 tcgctctaga cttgcatgag agagagcacc ttcgggacat tgagcattca ttgaaggcga 3019861 tagaaaacgg tacgtatggc atttgtgaag tcagcggaaa ggaaatccct ttcgaacgac 3019921 ttgaagcgct tccgactgcc acaaccctcg cggagtattc gtcacaggac gtggtttcca 3019981 aagaccgtcc gattgaagaa gaaacaccat tcgggcaatt tgaatttgat gatgatgaag 3020041 aaatcagagc gccatatgac agtgaggatt cctatcagga tgtcgaaaaa tatgggaact 3020101 cacaaacgcc gcaggatatg gaaaaccctc cgctcagcta tgatgatatg acgatgaatg 3020161 ccgaagagaa tatcggcaat acggagtctt acgaaaattt catcgctaca gatatcactg 3020221 ggaaagaaat taccgtttat caaagcagag cccatgagcg ctatgaagaa gaacttgacg 3020281 aagagggaat catgaccaca ttcggcgatc tccacgctga ttgaaccccc aattattggg 3020341 ggttcttttc cgttttcagc atatcgtaaa tcagcttcag ataatccttt tgcaggccga 3020401 tgtcataccg ctcgccctct agcaatttcc cgtatacggt acatgccccg agcgaagctt 3020461 ttatcgcatc cgttacctgc acttctcctc cgctatcagc ttctaatgcc tccagctcat 3020521 taaaaatatc cggtgtgaaa atataacgcc ctgctgcggc aaaatgagac ggagggtttt 3020581 gtttaggctt ttccacaata tcctgtatgc gataaagccc tttttcaaca ggctcccctt 3020641 ttatcacccc gtaatgatgt aaatcctccg tttttgtttc ttttaagccg atcacactgg 3020701 actgatattt cgtatacgct tcaatcagct gccccaaagc cggctgattg gcggaaaaaa 3020761 tcagatcatc tggcaaaacg acggcaaaag gctctcctcc tgcaaattgc tttccgaaag 3020821 aaatggcgtc gccaagaccc tttgcataag gctgccgcac atagtgaatc cgtatatccg 3020881 gaatgggatg ctctctaagt aaatgcagtt tattcttaga ggccaaaaaa gcctcaagtg 3020941 ccaaagagga atcaaaatag tcgacaatca gatttttatg gctcgataca accatcaaaa 3021001 tgtcctcaat gcctgactcc tttaattctt caacaagata atgaatcaca ggcttagatc 3021061 ctaccggaaa catttctttc ggaatcacct tcgtcaccgg cagatttctc gtgccgaatc 3021121 cgcctgcagg aatgatcgct ttttttatca tggtattttc ccctcagctc atgtttatta 3021181 catgatattc caagagcgca tcccgatgtt tgtacatctg aaattaggcg gaagcaactg 3021241 ggcagaaagc ggaatcacga accagccctt ttttaatagg atattgatat atgaccagta 3021301 atcttgtaaa ggagctcagg tgatgaaaat ttgtgtggtt ggcgccgggt atgtcggttt 3021361 aaccctatca gcggcactgg catccatcgg acatgacatg atatgcacag acaaagacgt 3021421 caaaaaaatc gggcagctga aaaaaggagt cattcccttt tacgagcctg ggctttcaga 3021481 tgcaatactt cgttgcggca atctctcgtt ttcttctgaa gtgaaatcga gcatggagga 3021541 atgtcccgtt atttttatcg cagtcggaac tccgccgcgt tcggacggat cagctgatac 3021601 gaaagccctg cagtccgtca tcggtgattt aagcgaggcg atccgatcgt ataaaaccat 3021661 tattacgaaa agcactgttc cgcccgggac aaatgaaaac atagcaaaac agctgattgc 3021721 ctccggagtg tctaaaaacc tctttaatat cgtatccaat ccggagtttc tgcgggaagg 3021781 caatgcctta tatgacatgc tgcatcctga caaaacagtc atcggtgttc aggaagaaga 3021841 tcacgtatcg gcagccatcg tcaaatccat ttacaaacac attgataccc cttttatcgt 3021901 tacaagctta gcgggagcag agctgatcaa atatgccaac aatttctttt tagcggccaa 3021961 aatttcgttc attaacgaaa tggcccgcat atgtgaagcc tatcaatcag atatctcaga 3022021 tatttcccgc gctatcggtc tagacccaag gatcgggaag cactttttgc aggcaggcat 3022081 cggatacgga ggctcttgtt ttccaaagga tctgcaggcg ctgcaatttg ctgcccagga 3022141 aaaaaacacg gagaccttcc tgctccgggc cgtgcagcac attaatgaca cccagcttgg 3022201 cctgtatatc aaaaaaatac agtcattctt cgaaacactt caaggcaaga aagcggctgt 3022261 actcggcatt tccttcaaac cgaatactga tgacatccgg aattctcagg ctgtcagact 3022321 gatggaaagg ctggcggagc tgggatgtga tgttcatgca tatgatcctg aagctgtact 3022381 tccagaacat ttgcggcaac atgtaactca gcattctcaa gcttttgatg cgatcgaaga 3022441 gagtgacttt ttatttttgg cgacagaatg gtctgagttt ttagcgtttg attggaaaaa 3022501 ggctgcagat atcatgaaag ggcgtcttgt gattgacgga cgcaacgtac taaaaaaaga 3022561 actgatcgag gcttgcggcc tgatctgtac gggagttggc cgtccatgaa aatactcgtc 3022621 acaggagcag cgggctttat cggctcccac ctctgcgaag aattactaaa agataagaaa 3022681 cataacgtta tcggaatcga tgactttatc ggtcctactc cattttcctt gaaattaaaa 3022741 aaccttaaaa acctgctgcc ggaaaagcga tttacgttca taaaggaaaa tctgctgaca 3022801 gccgatcttg cttccttact ggaaggagtg gacgtcatct ttcatttggc ggccataccg 3022861 ggtgtccgct caagctgggg caatcatttt cacccatatg ccgcacataa tatccaagcg 3022921 ctccaaaggc tcctcgaggc gtgccgggaa cattctattc aaacgttcgt ctttgcatcc 3022981 acctcttccg tctatggcga aaaacaagga aaagtcagcg aaaacacgtc gctttctcct 3023041 ttatctccgt acggggtaac aaagcttacg ggagaaaagc tttgccatgt gtataaacag 3023101 agctttggca ttccaattgt gattctccgt ttttttaccg tatacgggcc aagacagcgg 3023161 ccggatatgg cttttcaccg gctcattaag cagcaccttc agcaaaagcc gcttaccatc 3023221 ttcggtgatg ggcagcagtc aagagatttc acttatatca gcgactgtgt caaaggcatc 3023281 accgctgttc ttgggaaacc ccaccttatt ggtgaaacag taaatatcgg cggcgcagag 3023341 cgtgcctcag tcttaaaagt tgtctccctc attgaggata tttccgggag aaaagcaaca 3023401 ctgcactttt cggacaaaat agcaggggaa ccgagcaaca cgtgggcgga tatttcaaaa 3023461 gcaaaacagc tcttgcatta tgatcccgcc acatccttaa aggatggctt gaccaacgaa 3023521 atcgcctatt tatcgtcgct gtatcagggg gaataaaaat gaagcttgcc tttatctgta 3023581 cagaaaagct gccggcgccc gcagtacgcg gcggcgctat tcaaatgatg attgacggtg 3023641 tcacgcccta tttcagcagc aggtacgacc tgaccatttt ttcaatagaa gatccatcgc 3023701 tcccaaaaag agaaacaaaa gacggcgtac attatatcca tctgccaaaa gaacattacc 3023761 gcgaggcggt agccgaagag ctgcgagcct cttcctttga cctcattcat gtgttcaaca 3023821 ggcctttaaa tgtctcttta tataaaaaag cctcaccaaa cagcaagatc gttctgagcc 3023881 tgcataacga aatgttttct gaaaaaaaga tgaccttcgc gcaaggaaaa gaagtactcg 3023941 acaatgtctc catgatcaca acagtgagcg aatttattaa acaaaccgtc attgaacgtt 3024001 tccctgaagc cgaggacatc acaaaagttg tgtattccgg cgttgattta aactcttatc 3024061 cgcccgtctg gacgatgaaa ggctcggctg tcagaaaaac ataccggaaa aaatacggta 3024121 ttgaagataa aaaagttatt ttattcgccg gccgcttaag cccgacaaaa gggcctcacc 3024181 ttctcattca cagcatgaga cggattttgc agcagcaccc tgatgctgta ctggtcatag 3024241 caggcgggaa gtggttcagc gatgacagcg aaaaccaata tgtcacctat ctgcgcacgc 3024301 tggcgctgcc atacagagac cacataatct ttacaaaatt cattcccgca gacgatatcc 3024361 caaacctttt tctgatggca gatgtatttg tgtgcagctc tcagtggaac gaacccctcg 3024421 cccgtgtgaa ttatgaagca atggcggccg gcacgccctt aattaccaca aaccggggcg 3024481 gaaacggtga agtcgtaaaa cacgaagtca ccggccttgt catcgatagc tacaacaaac 3024541 cttcttcatt tgcaaaagca attgacagag cctttacaga tcaagaatta atgaacaaaa 3024601 tgacaaaaaa cgcccgaaag catgtagaag ctttatttac ctttacccat gctgccaaaa 3024661 ggctcaatac tgtttaccaa tccgttctga ccccgaaaaa caaacaattt ccgccgcctt 3024721 ttctgacgca aaattttgat ttatcatcta tcaatcagct ttttgtgaaa gcaaaaacat 3024781 aaaacctaca gctcgtgttg caaaacgggc tgttttttcg ctacagagaa cttaaaaaaa 3024841 ggcataaatg tgactttatg ccttgcgctt tacagtttga gaaaaccatg gagctggttt 3024901 agattcactt ggaagaatga tgatttccac tttagcttct tccgctaagt ctggttcttc 3024961 atcttcatcc tcttcttcat atgggggcgc tgagcgtttc gaatcacgct cctcctcagg 3025021 ctccagagtg gtttcgaatt ttgtttcttc ttcatcatcg acgattttgc gatctgtttc 3025081 cttttccttc gtttcttttt gatattcttt cggtgcattg atgtgaggga gctctcgaat 3025141 gctgcccaca tctaaatgct tctcctcttc ttccttctca gctgagattg agtcatgagc 3025201 ctgccatccc atcggtccag gcggtgtaaa tacgaattgg tcgagatcca gtttagaaat 3025261 agaggctttt tgtctcgatg acctcatgtc aattcgcctc ccgatacgct tttatctttt 3025321 tatacagttc cggcagttta tccaaaaacg aatctttaga ttcttcaaca gaaatcatgt 3025381 tttgcagcgc ccagttatac ttctcatctg accacgtttt cttttgcttc aaataatatt 3025441 tgtgcccgat tgcacagaac aaatgcggaa acgcgagatc aatccaaagt acctcgtact 3025501 gtttttctgt gagcggatac actgcgtcgt aggccgcaag cagtgcaacc atgaaatcag 3025561 tatcccatac agaaagctta accatcactt tattcagcag aatacgaagg tctcttgacg 3025621 gcaaatcgta ggtaatcgag tgaagctcct ttaaaaaagg ctccccttcg atctcagtca 3025681 aacgtgccaa tgtaaaatcc tgaaaacaga atccgccatg ctcgagtgtc tcttttgtcc 3025741 aggtttcgta ttctgagtca tcaagcgctc tgagagcttc ttttcctctt gccagcattt 3025801 tatcagcatg ttttaagaaa gtttgcgaaa atacgtcatc aggataggat gctgcgatct 3025861 gcatattccc ttcaagttcc tgcagcttcc aacggtacaa tttgtgccat tttcccagcc 3025921 tgcttctctt cttgctttca tctgtgcaaa catatccttt tgaggcatga tgaaaatggc 3025981 cggcaaatga catgactttt ttcatttgct ctgcatcata gtaaatcatt tcttttcctg 3026041 tcactttgtc atataaactg taagaaacct gatccgtgcc caagcagcta ccgccatttt 3026101 ttgtttgatg aatcggcgct atcggcagcc ctttctcttg taaatgggcg tgtgcctgag 3026161 tgataaaaag catccgctcc ggtttcattt gcgcttcttt tagcagcttt gggccatgat 3026221 cagtttcgac ttcccagatt ttgcgcccgc ttttgttcga tttcagcgcc acatggtcga 3026281 tatgaaacgg ataataactg agaatttcgg acacaatctg ttcttcatgc tctttttggt 3026341 acactctgtt caccccttct atctgttctt ttcatagacg ctgagcagat tttcagccac 3026401 cctctgccag ccaaaattgc tttctgcctc acggcggctg tatttcccaa gccgttcccg 3026461 cttttccgag ctgctcagca aatcattgat acgttcggca tattgtttag gattttcaaa 3026521 gtcatgaatg atgtagccgt ttttcccttc ctctatgacc tctggattgc ctccccgatt 3026581 gcttgtaata ataggaagtc ccgcagccat cgcttcataa tgcacccttg ctaaaggctc 3026641 ctgccattgc gaagagcata caaatacatc tgacatggta taaaggcgcg gaatgtcctt 3026701 tggcttcaca aattgaataa atgtgacatg atccttttgc atcgcaccaa gggtatgaag 3026761 atgtttgaca tagttattta attcattatc tccgaaccat tttgacccga taaacaccat 3026821 catgacatcg gggtgctcct caatgatgtc cggcaaagcc tgcaataata tgtgcgggcc 3026881 tttgactttg ctaagccggc cgacaaacaa gacgattttt ttgccgtgaa gccccagctc 3026941 gcttcgcatc tcttcgcgag ctcgctgccc ttcattcgtc cagcgagggt ggtacgtttt 3027001 taaatccaca ccagaataca ccgtttttgt ttttgatcgt gctgacggaa aacggcttgt 3027061 gatcgtctgt ccgatataat cgctgaccgt aacaatctgc gctacggagt cgatgcaaat 3027121 ctcgccttcc gcctggctga ttttatcgta agcgaacatt tcattgtgaa cgcttaaaat 3027181 aaaaacagca tccggcgcct gtttcttcaa tttcggaacc cagcttgggc gattacaaac 3027241 atgcacaaga tcaaaacggc tctttttcag ctctgctcca acggcttctt cataacggtc 3027301 ttcatccaaa tgcacataat ggacaccgtc taccttctct ctatcagcga gattcggatc 3027361 tttaatagaa aacacagtca cctcatgttt ttttgcaatt aaaggggcaa ccgcttcgag 3027421 gtagatttga atggcgcctc ctcgaaccga tgggacagga agcttctctg tggcgatcag 3027481 tgctattttc atacatagcc tccattcctg catgattttt aactagttag aatcatgata 3027541 cggctgaaca accaacttgt gcggaatggg actgccctaa aaacaaaacg ggtaaacaac 3027601 cagattcatc tattaaatat agtcaaataa ctcaatcatt ttttcctttt gattcataag 3027661 gtaggagtaa aacaggtaag gatgtgtcct ttaatggcag aaaaccatga agtcattgag 3027721 gaggggaatt catcagagct tcctttatca gcagaagatg caaaaaaatt aacggagctg 3027781 gctgaaaatg tgcttcaagg atgggatgtg caggctgaaa aaatagacgt cattcaggga 3027841 aaccagatgg cgcttgtctg gaaggtccac acagactccg gcgcggtttg tctaaaacga 3027901 atacacaggc cagaaaagaa agcgttgttt tccattttcg cgcaggacta tttagcaaaa 3027961 aaaggcatga atgttcctgg catactccca aacaaaaaag gcagcctata ttctaagcac 3028021 ggctcatttc tatttgtcgt atatgactgg atcgaaggaa gaccgtttga gctgactgta 3028081 aagcaggact tggagtttat catgaaaggc cttgctgatt ttcatacagc ttccgtcgga 3028141 tatcagccgc caaatggcgt tcccatattt accaaattag gtcgctggcc gaatcactac 3028201 acgaaacgat gcaaacagat ggaaacgtgg aagctgatgg cggaggcgga aaaagaagat 3028261 cctttctcac agctttatct tcaggagata gatggcttta ttgaagacgg gctgcgcatc 3028321 aaagaccggc ttttgcaatc gacctatgtt ccatggactg aacagctgaa aaaaagccct 3028381 aacctttgcc accaggatta cggaaccggg aatacactct taggagaaaa tgaacagatt 3028441 tgggtcatcg acttagatac cgtatcattt gatctgccta ttcgcgattt gcgcaaaatg 3028501 attattccgc ttttggatac gacgggtgtt tgggatgacg aaacatttaa tgtcatgctg 3028561 aacgcatacg aatccagagc cccattaact gaagaacaaa aacaagtcat gtttattgat 3028621 atgctgtttc cttacgagct ttacgatgtc attcgcgaaa aatacgtccg caagtctgct 3028681 ttaccgaagg aagaattaga atcagctttt gaatatgaac gcattaaagc aaacgcattg 3028741 cggcagctta tttaagacca tcatttcccc cgcatatcgg gggtttgata tttataagat 3028801 aaagggtaat taaatacatg cggaggttgc aaatatgaaa aagattgtcg gcgctttagc 3028861 cgtttttgtg attacatatg cgctgttttc agccgcaggc tacctgtttc ctgtggacca 3028921 agaatggtac aattcattga aaaaaccgga ctggacgcca agcggaactg cgatcggcat 3028981 catttgggcc atcctgtttg ccctgatctc cctttcagca gccattgtat atgctgcgtt 3029041 ttcatttaaa ggtgcgaaaa gcttttggtt tacacttttg ataaattacg tgctcaatca 3029101 agccttcagc tatttccagt ttacgcaaaa aaatctgctg gctgcatcgc ttgactgcct 3029161 gcttgtcgcc atcacagcaa tcgtattact gatcattgcc aaaaaataca gcagagccgc 3029221 aagctatctt cttttgcctt attttttatg gagtgcattt gcgacgttct tatcctttac 3029281 aatcaattca atgaatctgt gaacaaaaaa agccgcttat acagcggctt tttcacatca 3029341 tcggcttgat gccccaaatg tccttcgcat attcccggat cgtgcggtcg ctggagaaat 3029401 atccagaatg agcaatgttt acaatcgaat gctcagacca tttccttcgc tctcgataat 3029461 cagcttgaat tcgctcctgt gcatctgcat atgagctgaa atccttcagc acaaaatact 3029521 catcattatg cggaagcagc gagtcaaaga tcgattcaaa ttcatctgcc tctccttcaa 3029581 aaaaaccatt gatcaactga tccgctacct gcctgattct cctgtcatgc tgataatatt 3029641 ccctcgacct atagccgccg ttttcctgat acgatagaac ctcatccgcc tttaagccga 3029701 acgtgtaaat acagtcaggg cccacccgct caaggatctc gatatttgcg ccgtcatgcg 3029761 tgccgatcgt caaagccccg ttcatcataa acttcatatt ccctgtacca gacgcttcct 3029821 tgcttgcggt tgaaatttgc tcacttacgt ctgatgccgg aaaaattcgc tcagccatag 3029881 aaactctata attttctaaa aaaacaactt tgatcagctg tttgaccgcc ggatcataat 3029941 tgactttttc tgcgacagaa tggatcagct taatgatttt cttggcataa taatagcttg 3030001 gtgaagcctt tgccccgaaa ataaaggttt gcgggtagat tgaaaacccc gaatcctcct 3030061 tgaggcggtt atacaaatac ataatgtgaa gaacattcag cagctgccgt ttatatgcat 3030121 gaagccgttt cacctgtacg tcgaatatgc tctcagggtt cacaaccacc ccggccgtgc 3030181 aaaaaatcaa atcggcaagc tcttgttttt tcttgctttt gttgttttga aactgttcaa 3030241 taaatgcagg atcagtggcg tacggttcta aacggatcag tgattccggc tgcttgaccc 3030301 attcatcgcc gatcgcctct gtaatgatgg cagacaagcc tggattcgct tttaacagcc 3030361 agcgcctgtg ggcaattcca ttcgtcttat tgttaaaacg attcggaaac agcaagtgaa 3030421 agtcgcgcat ctccctttcc tttaatatat cggaatgtat ttttgcaacg ccatttacac 3030481 tgtagctgcc tactatggcc agatgagcca ttttgacaac accatgcgct gtaatcgcca 3030541 tgttctctat ccttttccag tctccaggat acttttccca aactgcacgg caaaacctct 3030601 cattgatctc ttcaataatc atgtacattc gcgggagcag cggcttaaac aaatgaatcg 3030661 gccatttctc gagcgcttct gacaatgttg tatgatttgt ataagaaatc gtatgtacag 3030721 tgatatgcca agcttcttcc cagctcatgt tctcttcatc gagcaaaatc cgcattagct 3030781 caggcaccgc aagcgcaggg tgagtgtcat taatatgaat gctcactttt ttatgcaggc 3030841 cggataaaga tttatgtgtt ttacggtaat tgttcacaat gctttttaag cttgcgcata 3030901 ctaaaaaata ctgctgcttc agccgtaaaa ttttcccctc atcatgggtg tcatcgggat 3030961 ataagaattc agaaaccgct tctgtttctc gcttataaga caaaatatta ccgccgtgat 3031021 aatgggcata gggctcggcg ttccaaagcc ttaacgtgtt gacagtgccc gtttcatagc 3031081 cgatgatcgg gatatcataa ggaacagcgg taacaattgt cgcttgttca tggcgaaaat 3031141 gcaggcgccc gcttttttct gtcatatgga cttcgcccca aaacggcacg tccactgctt 3031201 gatccgcatt ccttacttcc catacgttcc cgtttttcag ccattgctca ggcagctcca 3031261 cctgatgtcc gtctacaatt ttttgctcaa acaaaccatg cttataacgt atgcccatgc 3031321 cgtgcccagg caggttcaac gaagcaagcg aatctaaaaa gcaagcggcc aagcgcccaa 3031381 gtccgccatt gccgagacct gcatcgttct ctatctgaag gatctcctct aaattgatgc 3031441 cgatttcctt taaaccagct tctacaacat cacgaacacc aagattcatt aagttttgct 3031501 caaggagctg accgagcaga aattcgattg ataaataata tgtctgcttc ccggaatttg 3031561 atctgctttt ttcattcgtt tcgatccaat cagcgctgat atactctctg accatattgc 3031621 ccaacgtttt atattgatcc agcttggcag aatctttaaa gctttttccg cacgtcattt 3031681 ccagacgctt taaaaataag tctgcaaagc gttctttact cgagaacatc ccgtccactc 3031741 cttgtcacct gctcgaaaat acgctgatac tctttagccg acttccccca gctgtaatct 3031801 gcattcatag cggtcttcac gatgctcttc catacatcct gttggcaata aaacgacagc 3031861 gccctttcta tcgtaaattt cagatcatgc gcattaaagg cggaaaacgt aaagccattg 3031921 cccgttccct cttcctcctg ataggcacgg acagtgtcgt aaagaccgcc cgtttccctg 3031981 acaatcggaa tggcgccata ttgaagagca atgagctgcc ccaaaccgca cggctcaaat 3032041 ttcgacggca tcaaaaacat atcagagccc gcataaattt gatgggctag cggctcatca 3032101 aacccgatat aagcccggca cttctcatga aaagcaaatt ctgcataccg gaaataatct 3032161 tcaaattcac gttctcctgt gcctagcaca accagctgta tgtcttgctc ctcaagaagt 3032221 tcgtgcataa ttctgcggac aagatcaagc cccttttgtt tagtgagcct tgtcaccata 3032281 ctgatcagcg gaatatcgtt tttctctgga agccccatcc gctgctgaag cttcgttttg 3032341 ttttccagct tgcatgcaag atcccctgaa tcgtattgcg cctctatata agggtcgctt 3032401 ttcggctgat agaacgtatc atcaatgcca tttaatatgc cggttacatc atcttcccta 3032461 tattgcaaaa cctgttccaa ctgctcacca taatacggcg tcatgatttc atttctgtaa 3032521 gtggggctca cagttgtcac atgatcagcc gcaatgatgc ccgctttcat aaaattaaca 3032581 aatccgttgc attctaacct ttcataatga aaatgatcca tctcaagacc cagcaagtca 3032641 tgtgtgacat caggagggaa tatgccttga aactgcaggt tgtggatcgt gagcacgctt 3032701 ttcatccgtt cataaaaagg atgttttctg tactcctctt tcagcaaata attgaccatc 3032761 gctgtatgcc aatcgtgagt atgaacaata tcggcttgaa cattcacaac tttggcagcc 3032821 tccagcacag ctcttgaaaa aaaggcaaac cgctcaccgt catcataatg cccgtacaac 3032881 gaatccctgt tgaaatagta ctcattgtcg atgaagtaat aattcacatc attctctgcc 3032941 atatgttcaa ttccgcaata ttgctgccgc cagccgacag ctacggtaca ctcagcctgt 3033001 tttttcatac gctttttcca cggttcaggt atttggctgt acttcggcag catcacagct 3033061 acctcattgc ctaatcgcgc aagcgccttt ggcagagcac ctgctacatc ggcaagacct 3033121 cctgatttca caaatggggt gcattctgac acagcaaata atatcttcaa gaattcatca 3033181 gctctccttg caccaaacct tttcttaata caagcggctg ctcagctgtt cctgcagctt 3033241 ccgtcgcctt gccgatttta acatccttat ccgaaatgac ctgctcaaga agacaatcct 3033301 ctccaatctg cgttttttgc ataataatgc agtttttcag cttcgtaccc tttccgacat 3033361 ggaccgccct gaacaaaatg cagttttcaa cctctccttc aagcacacag ccgtttgcca 3033421 ccaaagaatt tttgacagtg ctgtgctttc cgtatttcgt aggcggctca tccttcactt 3033481 ttgtatagat cggctgctgc ggcaaaaaca cctgctgcca aaaacgaggc tgaatgagct 3033541 ccatactgtg ggtataatat ttttccaccg aatcaatgac agcggcataa cctgaatatt 3033601 cataagggca aatggtcagg gcggaagatt ccttttcaac agcctcctga atggttttat 3033661 agcctttttc gctatgtccg tagatcagat cctttaaaag cgttgttgac atgatataga 3033721 tttgcagcga ctggccgtcc tgaaatacct cggtgacgtc gcagccaacc tcctgatggc 3033781 gtttcagcac atattgaaat tgaatgttgc atacggtatg gctgttggag attacagcat 3033841 attgctgagt gcttctgtgg aagtaatcta gatggtccga aaactggcga aaggaaccga 3033901 attcatcgta ttcgtgatga agatggggag acgggaaaaa aaagaggccg tcctttttcc 3033961 ggtgcaaatc ccattcctta cccgccccaa ggtgatccat gagcgaacgg taacgatact 3034021 tcggaaaaat tgcaacactc ctaatatccg cattcaccat gttggaaagc ataaaatcaa 3034081 tcagtcggta cctgccggca aaagggatcg ccccgagcga ccgctgtgct gttaaatcct 3034141 gaagagaatg cttatatgtg gtttcatcta taacacctaa catttgatta ttgaacactg 3034201 actctgcccc ctcttcagta attaaatcaa ttctttttct acaaattcct ctgaaacgag 3034261 cagcacctct tcaatgtctt tttcggagcg aatcactgcg ccatccggca gcaccatccc 3034321 attaggaacg atggcatttt caatgactac atgctcccca atcgtcacat ccggcattat 3034381 gacggatgat gtaacagtcg tatgcttacc aacagtcaca ccttgaaaaa gaacggagtg 3034441 agacacattt ccatatacaa cacaaccttc gttcacaagc gaatcttgaa cctgcgcatc 3034501 agatgaaata aattgcggag gctgatttgg attgacggag taaattttcc atttgcgttc 3034561 aaacagcttc agctccgagt cctcttttaa caaatccata ttggcttccc acaagctctg 3034621 caccgttccg acatccttcc aatatccctt gaacggataa gcagaaagct tctttttctc 3034681 ttccaaaagc agtggaataa tgtctttgcc gaagtcgtgg ctagaataag ggttttgatc 3034741 gtccatctca agatactgtt tcaaaagcgg ccaattgaat atataaattc ccattgaggc 3034801 aagattgctc ttagggaatt tgggcttttc atcaaaatgt gtgatcgtcc catctggatt 3034861 ggccttcatg atgccgaacc ggcttgcttc ctcccagccc acttcgatga cagagatggt 3034921 cacatctgct ttcttttcaa tgtgataatc aagcattttg ccgtagtcca ttttgtatat 3034981 gtgatctcct gataaaatca gtacatactc aggatcatac tgattcaaat aattgagatt 3035041 ttcataaatg gagcttgccg tccctttata ccatttgact tctgatgact cggcataagg 3035101 gggtaaaacc gtcacgccgc cattatatct atccaggtcc catgcactgc cgatcccaat 3035161 ataggaattc agctcgagcg gctgatattg cgttaaaatc ccgactgtgt ctatgcctga 3035221 attagaacag ttgcttaggg taaaatcaat aatcctgtat tttcccccga aagatacagc 3035281 cggtttggcc atattttttg ttaatccgct gagacggctg cccttcccgc cggcaaggag 3035341 catggctaca cattgttttt tcatcttttt atctctcctc tttttttaac cgcccgtaaa 3035401 atcgagatgc cgtaaggggg gatggtcatc gtgatataac acggtttatg atgaagtgct 3035461 ccctttttag ccgataacgg ctttttgttg atttgccctg agcctccata tgtttcactg 3035521 tcactgttaa gcacttcaat gtattgagta aaaaaaggaa ctccaacatc atattgatga 3035581 tagaccacgg gtgtaaaatt acaaatgatg acaagcgcct caccgtgctt ttggccataa 3035641 cgaataaaag aaaagattga ttgttcgtca ttatggacat caatccattc aaacgattgt 3035701 gcacgatggt catgctcata aaggattttg cttttttggt aaaagcggag aagatcttgc 3035761 gtaaaaacgc tggctttctg atgcatgggg aaggagtcca aaaaccaatc aagctgttct 3035821 gtatctttcc attcatcaaa ttgagcaaac tctgatccca taaagatcaa tttctttccg 3035881 ggatgcactg tcatatagcc cagcaaaagc cgatactggg caaatttctg ccagtagtcg 3035941 ccaggcattt tattgagaag tgattttttt ccgtatacga cttcatcatg agaaaacggc 3036001 aatacaaaat gttcactaaa cgcatatagt aatgaaaaag agataagctg atgacaatgc 3036061 cgcctttctt cgggcggcgt ctccatgtat ttcagtacgt cattcatcca tcccatattc 3036121 catttataat gaaaaccaag ccccccttcc tcaacggcac ctgtcacttg aggccattct 3036181 gtagaatctt ctgcaatcat catcacatgg ggatatgcct ctctcatggt ttgattgagt 3036241 ttttttaaaa aatcaacagc atatggattc gtgtggcgtt catcctgatt tggccaatac 3036301 aagatattag ccactgcatc aaccctaaat ccatctatat gatagaattc cgcccagtac 3036361 aacgcattcg aaattaaaaa actatgaact tccggtttcc ccaggtcaaa gtttgccgtg 3036421 ccccataacc agttctcccg atcacgttct tctttgtatt cataaagcgg ttctccatca 3036481 aacatataaa ggccatgtgc atctttacaa aaatgtccgg ggacccaatc caaaatgact 3036541 ccgatatttt gttgatgaca ttcatccaca aacttcatca gatcatgcgg cgggccaaac 3036601 ctgcttgtcg ggctgtaata ccccgttcct tggtaccccc atgaacgatc atatggatgc 3036661 tcatacacgg gaagcagttc aatatgggta aacccatgct tcttgatata agggataagc 3036721 gtctgactta attctttata ggaataatgc ctgccatcag aatgcttctt ccaagaccca 3036781 agatgcagtt cataaatgaa aacaggtttt tcatacagcg tcttagcctt ctgtttcttt 3036841 tgccattttt gatcttgcca gctgtatcct tccaaatcgt aagtaagtga cgctgtgttt 3036901 ggtctgactt ctgaataaat agcgtatgga tctgccttca gcctgatctc accgttattc 3036961 gtcacaattt cgtatttata tcgttccttt tctcctatac ctggaataaa taacgtccaa 3037021 atgccattat cattcactct gtgcatcaca tgctcttctc cagaccagct gttaaaatct 3037081 ccagccactc gtacttccga cgcatgaggc gcccacacac agaattcata tccgcttttg 3037141 ccattcagct cgcggtaatg cgagccaaac agctgatagc ttttaaacag actgccttcg 3037201 tgaaaaagat aaacatcatg tgctgtcggg ctggcagcgg ccatgtaatc atcctttctg 3037261 acatcatagt tttcatttat agtatttatt cgaagaaata aaaaaaagcc ctttcctgaa 3037321 agcgcttata cttatagaca attaacttca ttttctgaag aaaaacgaaa tatatggaga 3037381 tttttgtagt ctgtttttaa aataaagaac aaaatctaag acatatcatg atttataaaa 3037441 acaaaaaaac cttgcaggat atgcaaggct tctggatgac ccgtacggga ttcgaacccg 3037501 tgttaccgcc gtgaaagggc ggtgtcttaa ccgcttgacc aacgggccga taattatgat 3037561 atctgtaatc atatggcgga gaaggaggga tttgaaccct cgcgccgctt acacgaccta 3037621 cacccttagc aggggcgcct cttcagccac ttgagtactt ctccatttgg ctccacaggc 3037681 aggattcgaa cctgcgaccg atcggttaac agccgatagc tctaccactg agctactgtg 3037741 gaacaaaagt catggtgggc ctgaatggac tcgaaccatc gacctcacgc ttatcaggcg 3037801 tgcgctctaa ccagctgagc tacaggccca tgacgatata gaaatggagc gggtgatggg 3037861 aatcgaaccc acgacatcag cttggaaggc tgaggtttta ccactaaact acacccgcaa 3037921 tttttatttg gggcgattga tgggaatcga acccacgaat gccagagcca caatctggtg 3037981 cgttaaccac ttcgccacaa ccgccaaagc atattgataa atggtggctc gggacggaat 3038041 cgaaccgccg acacacggat tttcagtccg ttgctctacc aactgagcta ccgagcctaa 3038101 gtatttaaat ggcggtccgg acgggactcg aacccgcgac ctcctgcgtg acaggcaggc 3038161 attctaacca actgaactac cggaccattt taaaatttgg ttgcgggggc aggatttgaa 3038221 cctgcgacct tcgggttatg agcccgacga gctaccgaac tgctccaccc cgcgatgatt 3038281 aggaatatgt atggcggagg aagagggatt cgaacccccg cgggctttga cacccctgtc 3038341 ggttttcaag accgatccct tcagccagac ttgggtattc ctccgtatag tggtggacct 3038401 tgtaggactc gaacctacga ccggacggtt atgagccgtc tgctctaacc aactgagcta 3038461 aaggtccatt ggtagcggcg gaggggatcg aacccccgac ctcacgggta tgaaccgtac 3038521 gctctagcca gctgagctac accgccaaat atttttgaaa tcaagtggag cctagcggga 3038581 tcgaaccgct gacctcctgc gtgcaaagca ggcgctctcc cagctgagct aaggccccaa 3038641 gaatggtcgg gaagacagga ttcgaacctg cgaccccatg gtcccaaacc atgtgctcta 3038701 ccaagctgag ctacttcccg atttcatata gatcatggcg cgcccgagag gagtcgaacc 3038761 cctaaccttt tgatccgtag tcaaacgctc tatccaattg agctacgggc gcaaaactta 3038821 atgccgaggg ccggacttga accggcacgg tagtcaccta ccgcaggatt ttaagtcctg 3038881 tgtgtctgcc aattccacca ccccggcgtg gatggtatag ttggagcgga agacgggatt 3038941 cgaacccgcg acccccacct tggcaaggtg gtgttctacc actgaactac ttccgcagaa 3039001 atggtgcgga tgaagggact tgaaccccca cgtctgtaaa gacactagag cctgattcta 3039061 gcgcgtctgc caattccgcc acatccgcaa catgtaaatg gtgagccatg aaggactcga 3039121 accttcgacc ctctgattaa aagtcagatg ctctaccaac tgagctaatg gctcttctta 3039181 caatagactt gaatattata tcatataaaa gtggtgccgg caagaggact tgaaccccca 3039241 acctactgat tacaagtcag ttgctctacc aattgagcta caccggcata tatgtaaaac 3039301 cgatatgtat aatgaaaaat ggtggaggat gacgggctcg aaccgccgac cctctgcttg 3039361 taaggcagat gctctcccag ctgagctaat cctccatact tgcactaacg tgcaattgct 3039421 tggcggcgtc ctactctcac agggggaaac ccccgactac catcggcgct gaagagctta 3039481 acttccgtgt tcggtatggg aacgggtgtg acctcttcgc tatcgccacc aaacaaattg 3039541 agagtgttct ctcaaaacta gataacaggt gtgacatcat tcaaaaatat ggttaagtcc 3039601 tcgatcgatt agtatctgtc agctccatgt gttgccacac ttccacctca gacctatcaa 3039661 cctgatcatc tttcagggat cttacttcct tgcggaatgg gaaatctcat cttgaggggg 3039721 gcttcatgct tagatgcttt cagcacttat cccgtccgca catagctacc cagcgatgcc 3039781 cttggcagaa caactggtac accagcggtg cgtccatccc ggtcctctcg tactaaggac 3039841 agctcctctc aaatttcctg cgcccgcgac ggatagggac cgaactgtct cacgacgttc 3039901 tgaacccagc tcgcgtaccg ctttaatggg cgaacagccc aacccttggg accgactaca 3039961 gccccaggat gcgatgagcc gacatcgagg tgccaaacct ccccgtcgat gtggactctt 3040021 gggggagata agcctgttat ccccggggta gcttttatcc gttgagcgat ggcccttcca 3040081 tgcggaacca ccggatcact aagcccgact ttcgtccctg ctcgacttgt aggtctcgca 3040141 gtcaagctcc cttgtgcctt tacactctgc gaatgatttc caaccattct gagggaacct 3040201 ttgggcgcct ccgttacctt ttaggaggcg accgccccag tcaaactgcc cacctgacac 3040261 tgtctccccg cccgataagg gcggcgggtt agaaggtcaa tacagccagg gtagtatccc 3040321 accgatgcct ccaccgaagc tggcgctccg gtttccaagg ctcctaccta tcctgtacaa 3040381 gctgtaccaa cattcaatat caggctgcag taaagctcca cggggtcttt ccgtcctgtc 3040441 gcgggtaacc tgcatcttca caggtactat aatttcaccg agtctctcgt tgagacagtg 3040501 cccagatcgt tgcgcctttc gtgcgggtcg gaacttaccc gacaaggaat ttcgctacct 3040561 taggaccgtt atagttacgg ccgccgttta ctggggcttc aattcgcacc ttcgcttacg 3040621 ctaagcgctc ctcttaacct tccagcaccg ggcaggcgtc agcccctata cttcgcctta 3040681 cggcttcgca gagacctgtg tttttgctaa acagtcgcct gggcctattc actgcggctc 3040741 tctcgggctt gcaccctaac agagcacccc ttctcccgaa gttacggggt cattttgccg 3040801 agttccttaa cgagagttct ctcgatcacc ttaggattct ctcctcgcct acctgtgtcg 3040861 gtttgcggta cgggcacctc tcacctcgct agaggctttt cttggcagtg tggaatcagg 3040921 aacttcgcta ctatatttcg ctcgccatca cagctcagcc ttatgggaaa cggatttgcc 3040981 tatttcccag cctaactgct tggacgcgga tatccaatac cgcgcttacc ctatcctcct 3041041 gcgtcccccc attgctcaaa tggtgaggag gtggtacagg aatatcaacc tgttgtccat 3041101 cgcctacgcc tttcggcctc ggcttaggtc ccgactaacc ctgagcggac gagccttcct 3041161 caggaaacct taggcattcg gtggagggga ttctcacccc tctttcgcta ctcataccgg 3041221 cattctcact tctaagcgct ccaccagtcc ttccggtctg gcttcacagc ccttagaacg 3041281 ctctcctacc actgttcgaa gaacagtccg cagcttcggt gatacgttta gccccggtac 3041341 attttcggcg cagagtcact cgaccagtga gctattacgc actctttaaa tggtggctgc 3041401 ttctaagcca acatcctggt tgtctaagca actccacatc cttttccact taacgtatac 3041461 tttgggacct tagctggcgg tctgggctgt ttccctttcg actacggatc ttatcactcg 3041521 cagtctgact cccaaggata agtcattggc attcggagtt tgactgaatt cggtaacccg 3041581 gtaggggccc ctagtccaat cagtgctcta cctccaagac tcttaccttg aggctagccc 3041641 taaagctatt tcggagagaa ccagctatct ccaggttcga ttggcatttc acccctaccc 3041701 acacctcatc cccgcacttt tcaacgtgcg tgggttcggg cctccattca gtgttacctg 3041761 aacttcaccc tggacatggg tagatcacct ggtttcgggt ctacgaccac gtactcatgc 3041821 gccctattca gactcgcttt cgctgcggct ccgcatcttc tgcttaacct tgcacgggat 3041881 cgtaactcgc cggttcattc tacaaaaggc acgccatcac ccgttaacgg gctctgacta 3041941 cttgtaggca cacggtttca ggatctcttt cactcccctt ccggggtgct tttcaccttt 3042001 ccctcacggt actggttcac tatcggtcac tagggagtat ttagccttgg gagatggtcc 3042061 tcccggattc cgacggaatt tcacgtgttc cgccgtactc aggatccact caggagagaa 3042121 cgaagttttg actacagggc tgttacctcc tatggcgggc ctttccagac ctcttcatct 3042181 acctcgttct tttgtaactc cgtacagagt gtcctacaac cccaagaggc aagcctcttg 3042241 gtttgggctg atcccgtttc gctcgccgct actcagggaa tcgcatttgc tttctcttcc 3042301 tccgggtact tagatgtttc agttccccgg gtctgccttc tcatatccta tgaattcaga 3042361 tatggatacc actccattac gagtggtggg tttccccatt cggaaatctc cggatcaaag 3042421 cttgcttaca gctccccgaa gcatatcggt gttcgtcccg tccttcatcg gctcctagtg 3042481 ccaaggcatc caccgtgcgc cctttctaac ttaaccgtta aaaagaatca ctatgtgata 3042541 tcttgtgtta ctaattgaat gtgatgtcta ctgttatcta gttttcaaag aacacgtttc 3042601 gaaggaatga tccttcaaaa ctaaacaaga cagggaacgt tctgtttata agaccttggg 3042661 tcttatattc cgtataatat ccttagaaag gaggtgatcc agccgcacct tccgatacgg 3042721 ctaccttgtt acgacttcac cccaatcatc tgtcccacct tcggcggctg gctcctaaaa 3042781 ggttacctca ccgacttcgg gtgttacaaa ctctcgtggt gtgacgggcg gtgtgtacaa 3042841 ggcccgggaa cgtattcacc gcggcatgct gatccgcgat tactagcgat tccagcttca 3042901 cgcagtcgag ttgcagactg cgatccgaac tgagaacaga tttgtgggat tggcttaacc 3042961 tcgcggtttc gctgcccttt gttctgtcca ttgtagcacg tgtgtagccc aggtcataag 3043021 gggcatgatg atttgacgtc atccccacct tcctccggtt tgtcaccggc agtcacctta 3043081 gagtgcccaa ctgaatgctg gcaactaaga tcaagggttg cgctcgttgc gggacttaac 3043141 ccaacatctc acgacacgag ctgacgacaa ccatgcacca cctgtcactc tgcccccgaa 3043201 ggggacgtcc tatctctagg attgtcagag gatgtcaaga cctggtaagg ttcttcgcgt 3043261 tgcttcgaat taaaccacat gctccaccgc ttgtgcgggc ccccgtcaat tcctttgagt 3043321 ttcagtcttg cgaccgtact ccccaggcgg agtgcttaat gcgttagctg cagcactaag 3043381 gggcggaaac cccctaacac ttagcactca tcgtttacgg cgtggactac cagggtatct 3043441 aatcctgttc gctccccacg ctttcgctcc tcagcgtcag ttacagacca gagagtcgcc 3043501 ttcgccactg gtgttcctcc acatctctac gcatttcacc gctacacgtg gaattccact 3043561 ctcctcttct gcactcaagt tccccagttt ccaatgaccc tccccggttg agccgggggc 3043621 tttcacatca gacttaagaa accgcctgcg agccctttac gcccaataat tccggaaaac 3043681 gcttgccacc tacgtattac cgcggctgct ggcacgtagt tagccgtggc tttctggtta 3043741 ggtaccgtca aggtaccgcc ctgttcgaac ggtacttgtt cttccctaac aacagagctt 3043801 tacgatccga aaaccttcat cactcacgcg gcgttgctcc gtcagacttt cgtccattgc 3043861 ggaagattcc ctactgctgc ctcccgtagg agtctgggcc gtgtctcagt cccagtgtgg 3043921 ccgatcaccc tctcaggtcg gctacgcatc gttgccttgg tgagccgtta cctcaccaac 3043981 tagctaatgc gccgcgggtc catctgtaag tggtagccga agccaccttt tatgtttgaa 3044041 tcatgcggtt caaacaacca tccggtatta gccccggttt cccggagtta tcccagtctt 3044101 acaggcaggt tacccacgtg ttactcaccc gtccgccgct aacatcaggg agcaagctcc 3044161 cacctgtccg ctcgacttgc atgtattagg cacgccgcca gcgttcgtcc tgagccagga 3044221 tcaaactctc cgataaatgg atcacaggtt aagttcaccg catcctgcgg cgacacctgt 3044281 gtgacctgcg tcgtgcaggc cctagtttga ctgactacgc acatcgcagt gcgattttta 3044341 aaaactgaat taacaggtac gttttgtctt gtttagtttt caaagatcat ttcgttactt 3044401 ctcaatgaag cagctttact aatataacat tcagcttctt ttttgtcaac aacttttttc 3044461 aagttgtttt gaagcatcta gtttgtgtcc gctgtgcatc agcgacgttt aataatataa 3044521 cacctgtatt tatttattgc aatagttttt taaaaaaaat ctataaaaca aataaactat 3044581 aatcctcgcc atgatttcta aagcgtgtgt atcatataag tttcttaaaa gaacatatac 3044641 atcagtcatg tgatcttgtt gtttttttcg ttttcttgta tagtagaaac gaactaaata 3044701 ctgatgacca caaggggagc attaaagctg agagtgagcg gtttcgttct gaccctttga 3044761 acctgttagt taacgctggc gtagggatgt ggcaaagtca aatgaattgc agatcgtaaa 3044821 gcagtgcgtg gaacttttct catccttccg cgtgctgctt ttttgttgtc cttttggttg 3044881 tctgtcaatg gaaggagata gatatgaatc aatctaagca actggttcgc cttattgaaa 3044941 ttgccattat gacagcggca gccgttattt tagacattgt ctcaggaatg tttcttagca 3045001 tgcctcaagg aggctcggtc tccatcatga tgattccgat ctttttaatt tcgtttcgct 3045061 ggggtgtcaa agcaggtctt actacaggtt tgttgacagg tctagtacaa atagcaatcg 3045121 gaaacttgtt tgctcaacat cctgtacagc tattgttaga ttacattgtc gctttcgcag 3045181 caatcggcat aagcggctgt ttcgcttctt ctgtccgtaa agccgctgta tcaaaaacaa 3045241 aagggaaatt gattgtttca gtggtcagcg cagtttttat cggcagtttg ctgcgctatg 3045301 ccgcgcatgt catttcagga gctgtgtttt tcggcagctt tgctccaaaa ggaacaccgg 3045361 tatggattta ttctttaact tataatgcga cttacatggt tccttcattc attatttgtg 3045421 caattgtcct atgtttatta tttatgacag caccccgtct gcttaaaagt gacaaagcgt 3045481 aaaagtaaca atcccccagc gaattccgct gggggatttt tcgttatctg ttaagaagtg 3045541 tttttaaagc tgaaagatcc ggccagccaa gacctacttc tttcagcctt actccggcaa 3045601 tttcaaagtt gtcctccgct actctttcag gtgaataggc ctgataaaat ataatcgagg 3045661 gattctgctc aataacccaa acaaacatac ttgaaaaacc atgttgaagc aaaaactccg 3045721 ctccttttgc taagagcgcc ctgcctgcac cttgccgctg gcgctcttcc agaagataaa 3045781 tagcgtataa ctcgccgtca tagccttctt gttcagagcg aataggtcca aatgaagcaa 3045841 agccgaatac tgaacccttt tcgtcctgag caacaaatac tccctttaac gagcgacttt 3045901 tccatttgtc ttcaaattcc ttatagttca ggctgtttaa ataatcaatc gggataattt 3045961 cgtggtatgt tgtcctccag ctgtctacat gcacttttgc aatgtccttt atatcctcta 3046021 acttcgcttc acgtacagtt accatacggt tctgcccttt ccttactctg atttttggat 3046081 cgttttggct tctttgattt catttgttaa ttcattaatg ctttgtttta cgtttccttt 3046141 tcctgaaaag ttctcaagca tttcttttac atcaattcct gaggatgctt ttaaactttc 3046201 ttgcagactt gacattaagt tcgtcgcata gctggttact ttgtttgctc cgcttgattc 3046261 accgcttcct cctgtatcga caacggtgat tttatcaata tttgaaagag gtgccgctgc 3046321 ttgtttcgcg tattccggaa gcattttgac aatcatatcg aaaatcgccg cctgcccgta 3046381 ctgttcaaag gcggccgcaa ttttctcttt tgcttccgct tctgcaagac ctttcaggcg 3046441 gataacctct gcttctgtct ctcctttcgc tttttccgct tctgcttttg ctagcccgtc 3046501 aattcttact ttttccgcct cagcctttgc cattgcttca atactgtact tcttggcatc 3046561 ggcttccgcg agctgtttgg ctttctcagc tgctgcggac tgctcaacag aataacggtc 3046621 tgcatcggct tttttcttta cctctgagtc gtattgacgt tcacggcgaa gaatttcttt 3046681 ttcttctagt tctatttgtt tttggcgttc gataatttta acctgcattt cctgctctgt 3046741 gacttgctgg cgcgctcggg cagtctctaa atcatatgct tggtcggcat tcgcttttgc 3046801 cgtatcttgt tctctgcgga attcagccat tttgagctga ttgatttttt cagcttcagc 3046861 gatttccgtc gcccgttcaa gttctgattt ttttgcgtct ttatcggctt ctgcccgctt 3046921 aattcgggtt tctttatcag cctctgctgt tgcgatatca gcatcgcgtt ttacttgggc 3046981 aattctcggt ttccctaatg attcaagata accgttttta tcacgaacat ctttaatggt 3047041 aaacgagacg attacaagtc ccattttcgc gagatcctgt gaagcgacac gctgcacctc 3047101 ttgagagaat ttttctctgt ttttatagat ttcttctact gtcattgagc cgagaatgga 3047161 acgaaggtgg ccttctaaaa cctcccgcgc ttcctgctca cggtcgtctt ttgatttccc 3047221 taaaaattgt tcggccgctg tagcgatttc tcctatagaa ccgccgattt taataatcgc 3047281 agttccatcg gccattactg gcactccttg ttctgtatag acttcaggtg tcgaaacatc 3047341 gagtttgctt gataataggc ttagcggctc tgcctgctgg aagacgggaa ggacaaaggt 3047401 tcctccgccg cggacgattt taatacggtt gccgccttca tcgacatgaa catttttatt 3047461 acccagatag ctccctgtta caattaacgc ttcatcaggc cctgctgtac gatacttcgt 3047521 aataaacaca gctattagtg caattaataa aaagaataca actccgatga tcattataat 3047581 cggcattgtc atatcaaatt cctcctttta tgttaaatgg gttcatgcgg agtaaccgaa 3047641 agaactccgt tgttaatatc tacgactaac accgttgtcc cgtaactgat ctgctgatta 3047701 tcaaaactga ccgctgactt tgaaatggtc ccgcctatcc cttctatgac cacttcacca 3047761 aacccgtcaa ccggcacagc tgtaatcact ttaccgagtc ttcctctgag atcatcttct 3047821 ctatatgcca atgattcttc tgcagatgat aatggcacca gtacaaagat gtgaagcaat 3047881 accaccagca tgatcgaaag gatgcaagat aaaagcgcaa tcagcaagct tgacagaggc 3047941 aatacaagtt cacctatata tccgcccgct gaaaaacatg taaaaaatga gagcactaat 3048001 gtcggattaa gaaacggaat gccttctgac agccctgaaa atacatctcc gaaaaacagg 3048061 aataacagcg taaggctgcc cgcaataata agcgtataaa gatacattgt ttgtataggt 3048121 actccaaata actccaactt cctcatcctt tcttcatcaa tgcattgatg aacggctgcc 3048181 gttaccattt atacgagaca cctcgggaaa agtttcaaaa ttttaagaca aataacccat 3048241 ttgaagtgct ttataaatga taattgctta tatatatggt aatgtcattt taggaggaga 3048301 tatgatgagt atctttaatg aagccagatt agaaacgtgg aacgaattga aaggactttc 3048361 tgacgaaaag ctgaatcaaa agccttctgc tgaagaatgg agcatacggg aagttcttga 3048421 ccatttgaaa aaaatcgata tgaccgcaca aaaaatgttg aaggaacgtg taaaggacgc 3048481 tccgattaaa gaaattgaag aaaaaccgct tgaagtagca caggacagaa ataataaacg 3048541 gaaagccccg agtcatcttg agcctgcgca tgattttatt tcaggcagcc aaatgaaacg 3048601 tgagcttgat gtggtaagag agcagctgac tgctgcgatt gcctctctga aagaagaaga 3048661 ttttgaaaga gtgcttccgc atcctgtgtt tcaagagctg actgtcagac agtggatcga 3048721 ttttatcggc catcatgaaa aacggcacct cagccaaatg aaagaaatta aagaaaagat 3048781 agaaagggcc tgatttaatc agaccctttc tgcttttcgt ttgacttttc gctgatagga 3048841 atgaacttct atttcatcac ctgtgtaaac agcaccaggt ctctccacaa tacagacaat 3048901 ccctctaatg cccagtgcgt ggcggacgaa agccgacgcc agcttcggtt ggtccggata 3048961 ataagactga atgacttctc ccggctggat acacggatca ttttcgccct cacacagcag 3049021 agccgctccg ctcggaaaaa taatccggct tccttctttt aatgaagtaa gatctggcat 3049081 accgctgact gccacattcg ccccgagcca ttccggcaaa attctcggca ctcccatttt 3049141 taaagcgatt tcgttgcatt cctctattga aacaattgaa atttgtctgc ggttgaaaat 3049201 ttcagtccct cttgaaaaca ttggttctct ggctcccgct tttttggtca ggccaaaatg 3049261 caagtcgccg gggatgccgc cataatcaaa atcaagcttg tccatttgct ttgttacgaa 3049321 gctttttgta tctgcgatat ataagccttc cgcttttgca gtcatacgct tccacatcag 3049381 ctggcacctt ccttcttatc taaaatttcc acctatgctt cattatccca aaaaatcccg 3049441 ctctgtaaag gagcgggatt ttgattatac cgttttaggc gtaaggttaa agcagcgttt 3049501 gtagatccag ttgtatgctt tttcatttaa atctctaggg tttccgaagg tttgcggatc 3049561 tttcattgct tctttagaca agcgttcgat catatcaggt gatactccct gctcttctaa 3049621 agtcggcact tctaaatctt cgaccagatc atacatccaa ttgacagatg ctttcgcagc 3049681 ttcttctgtt gtcatcttgc ttgtatcaat accgaacgct ttcgcaatac gcgcaaactt 3049741 ctcaggatag cccttccagt tgtattccat gacagggccc atcatcgccg ctacacattg 3049801 gccgtgagcg actgggataa taccgccaag cgtttggctc atcgcatgag cagcgcccgc 3049861 tgattcactt ccgtaagaaa gaccggcaag catcgcagcc tgcgccattc cgtaccttgc 3049921 ttccagatcc tctccatcag caaatgccct cttgatgtaa tgagcggcat actcaatcgc 3049981 cattaaggca accgcatccg tgattggctg tgcaaatttc attgtatagc actcaatggc 3050041 atgggcgagc gcatcaattc ccgtcatagc tgttacatgc ggaggcattg aaacatgaag 3050101 ctcaggatca atgattgtca agtgcgctgc aatcagcgga ccgcccgtgt tgaatttgaa 3050161 ttctctttct tcatctgtga taaccgccca ttgggttact tctgatccgg ttccagctgt 3050221 agtgggaatt gtcgtcagcg gaggaatgcg gttttccagc ggttttttcc catctgccgc 3050281 ttcataatca agcacgcttc cttcgtgagt cgcttctact ccgattgctt ttgctgtatc 3050341 catggagctt ccgcctccga ctgccaccaa accattacag ttctcttttt tgtaaagctc 3050401 agatccttca ttcaccagac ggacaggcgg gtttggctca actttattaa agagtaccac 3050461 ttcaatgcct gcttctttaa gtgattcgat tacgggatca gcaacaccgg ctttataaat 3050521 cccagggtct gtgacaagga gcgcttttga aacgcccagt gcagctactt cctcacccgt 3050581 atgcttgatg gctccgattc catgcttaat cacagtcgga atttcaaatg tgtggaattt 3050641 ctgcatgctt tctaccttca tatttaatgt catcatcaat ctccccctct tatgaattaa 3050701 accagttaac cgctgccggt tttgtattgc ggtatacatg tttgacttct gtgtattctt 3050761 caaggcctat ttttccaagc tcgcgtccga acccggattg cttatatccg ccccatggcg 3050821 cttgtgcaaa gtacggatga aaatcgttga tccaaacggt tcccattctc aagcgggctg 3050881 ctacccgttc gcacttttca atgtcttttg accataccgc tccagccaag ccatagatgg 3050941 tatcattcgc aagctcgatt acctcttctt cagagctgaa ggtttcgact gtcaatacag 3051001 gaccgaaaac ctcttcctga acgattctca tgtcagaatt acagtttgag aaaatagtag 3051061 gttcatagaa aaagccgttt tgaagctcag gatcttccgg gcgtttgcct cctgtctcca 3051121 gcttcgcgcc ttcctctatt ccgatctcta catatttttc tacctttgcc ctgtgctccg 3051181 ccgaaataag cggaccgctt tctgtctcag catgaaaacc gtttccgagt tttatgcgtt 3051241 ttgcccgttt gaccagctcc gccaaaaatt gatcatgaat ggcatcctca acaagcaagc 3051301 gggaacctgc agagcatact tggccggcgt ggaaaaatac agcgtttaag gcctgatcaa 3051361 ccgcaacttc taaatccgcg tccttgaaaa caatatttgg gtttttcccg ccaagttcaa 3051421 gggcgatttt tttgacgttt ccgcttgccg cccgcatgat ttttttgcct gtttcaattc 3051481 cgcccgtaaa tgaaatcaaa tcgacgtctt tgtttacggc aagctcgtcg cccactgtgg 3051541 ctcccggtcc aagaacaaga tttgcgacac cttttggaac accggcttct tccatcagct 3051601 taaagacttt gattgtcgtc agcggcgtaa tctcactcgg cttcatgacg attgtgtttc 3051661 ctgcggccag tgcaggggcg attttccagc tcgcttgaag gagcggataa ttccatggag 3051721 tgatctggcc gcaaaccccg attggctccc taataatttt gctttctgaa tcaggaatcg 3051781 gagatgaaat gatctctccg ccatctttgt ctgccaagcc ggcgtaatat tgaaaaacat 3051841 tggcgatatc gtccatatcg gccttgcttt cttcgagtgt ttttcctgta tcaagagatt 3051901 caagctcagc cagctcctca agatcgcgtc tgattaattc cgcaattttc agaacaattt 3051961 ttccgcgttc aagcccggat agcgatgacc attctccttt gtcaaatgct ctacgtgcgg 3052021 ctgcgattgc tttgatggcg tcctctcgcc ctccctcgct tacagttgca atttcttctt 3052081 gattaaatgg gttgataata ctgcggatct gttctttttc ggcactgatc cattctccgt 3052141 caatgaataa tgtttgactc atataagcct ccttgacgta aataaagttt gttaaataaa 3052201 aatttaatgt ttttaacaac cttaatctaa catatggttt ttaaactgtc aaagtcccat 3052261 tttgattttt ctttttgact tttcctcatg tttcgttaag ataaagaaca taaagaaata 3052321 acttaacgaa tttaattttc taaaggaaaa gagggtcagt atggatgaaa atccagaatt 3052381 tgcagctata gaacaggctc gggatcttgt tattgactcc attgctgaaa cgatggatct 3052441 ttacggaatt acccgcagtg tcgggatttt atatgggacg atgtatatga gggatgagat 3052501 gacgcttgac gaaatgcgtg aggagttgca aatgagcaaa ccaagcatga gcactggcgt 3052561 caaaaagctt caagacttaa atgtagtgaa aaaaacattt caccggggca tccgcaagca 3052621 tacatttgtg gctgagaagg atttctttaa atttttcaca aatttctttc cacctaaatg 3052681 ggagcgggag gttcaagtga atgtaacagc gatcgaggaa gctcaagctg atttacaaaa 3052741 ggttttatgc aaggaagatc tcgatgagga tatcaaaaat gaagcactgc agttatatga 3052801 tcagctggaa agctctaaag cttactatga ctggctgaaa cggcttgctg aatcggtgca 3052861 gaccggagaa atttttaaat ttataccggt cgaaacaaag taaagcagaa aacgcctggg 3052921 aaactaggcg tttttttgat gtaactacta caaatttgaa aaatacggga aaaacacccc 3052981 atttacttcc aaaatatttg atggtaattt tatgtaggta aaatttgtat ttggcctttc 3053041 agaggaggtg aaaagcgggc aggcctgttt aatttatcat tttttagggg gaattttgtt 3053101 atgaaacgca aattattatc ttctttggca attagtgcat taagtctcgg gttactcgtt 3053161 tctgcaccta cagcttcttt cgcggctgaa tctacatcaa ctaaagctca tactgaatcc 3053221 actatgagaa cacagtctac agcttcattg ttcgcaacaa tcactggcgc cagcaaaacg 3053281 gaatggtctt tctcagatat cgaattgact taccgtccaa acacgcttct cagccttggc 3053341 gttatggagt ttacattgcc aagcggattt actgcaaaca cgaaagacac attgaacgga 3053401 aatgccttgc gtacaacaca gatcctcaat aacgggaaaa cagtaagagt tcctttggca 3053461 cttgatttgt taggagctgg cgaattcaaa ttaaaactga ataacaaaac acttcctgcc 3053521 gctggtacat atactttccg tgcggagaat aaatcattaa gcatcggaaa taaattttac 3053581 gcagaagcca gcattgacgt ggctaagcgc agcactcctc cgactcagcc ttgcggttgc 3053641 aactaatgta aaagaccggt taacgccggt cttttttgcg ttttaccctc ccctttttct 3053701 ctaatccccg ttatcttttt tctggtttaa aatttaaatt gacaaacact agaaacagga 3053761 gtaaattctt gagtgttcaa tttcatacag tctcttttac cgcttaatca aacacgaacg 3053821 ggggaaccaa cgattggctg ttttattaac agccttgggg tgaatcttac taagtaagag 3053881 ggggtactct gaatccctaa tccgacagct aacctcgtag gcgtatacag agaggaggtc 3053941 tattatcggc cattctttgc aatggtcttt tttgtttcaa aaacgttaat tcactaaggg 3054001 agatatgaac attgggaaga attaaaaata agcaatttgc cgtgatcggg ctgggccggt 3054061 ttggcggcag catttgtaaa gaacttcata gaatggggca tgaggtcctt gcggttgata 3054121 tcaacgaaga aaaggtcaat gcatatgctt cttacgccac tcatgcggta attgccaacg 3054181 ccaccgaaga aaacgaattg ctttcattag gaatacgcaa ttttgaatat gtgattgttg 3054241 ccatcggagc aaatattcaa gcgagtacgc tgaccaccct attattaaag gagcttgata 3054301 ttccaaatat ttgggtgaag gctcaaaact attatcatca caaggtgctt gaaaaaatag 3054361 gcgctgaccg cattattcat cctgaaaaag atatgggggt taaaatcgca caaagccttt 3054421 cagacgaaaa tgttttgaat tacattgatc tatctgatga atacagtatt gtcgagctgc 3054481 tggctacgcg caagcttgat tcaaaatcga ttattgacct gaatgtaaga gcaaagtacg 3054541 gctgcacgat cctggccatt aaacatcatg gagatatctg tctttccccc gcgcctgaag 3054601 acatcattcg cgagcaagat tgcctggtga tcatgggcca caaaaaggat attaaacgtt 3054661 ttgaaaacga agggatgtag acaaaggtga cacttcaaaa ggataaagtg atcaaatggg 3054721 ttcggtttac accgcctcaa gtgcttgcca ttggtttttt ccttaccatt atcatcgggg 3054781 ctgtcctatt aatgcttccg atttccacta cgaagccatt gtcatggata gatgcccttt 3054841 ttactgcggc ttccgctaca actgttacag ggcttgctgt tgtcgatacc ggcactcaat 3054901 ttacggtatt cgggcaaaca gtaattatgg ggctgattca gattggcggg cttggattta 3054961 tgacatttgc ggtcttgatc gtcatgatat taggaaaaaa aatcggctta aaagaacgaa 3055021 tgctcgtcca ggaagcctta aaccagccga caatcggcgg tgtcattggc cttgtcaaag 3055081 tcctgtttct gttttcgatc agtattgaat tgatagcagc actcatttta tccatccggc 3055141 ttgtacctca atacggctgg tcatccggct tgtttgcaag tttgtttcac gcaatatctg 3055201 cttttaacaa tgccgggttt tcgttgtggc ctgataattt gatgagctac gttggcgatc 3055261 ctacagtgaa cctcgtgatt actttcttat ttattacagg agggatcgga tttacggttc 3055321 tgtttgatgt gatgaaaaat cggcgtttta aaactttttc tttacataca aagctcatgc 3055381 ttacaggaac gctgatgttg aatgcgatcg ctatgcttac ggtctttatt ttagaataca 3055441 gcaaccccgg cacgctcggc cacctgcata tagtggataa actgtgggcc tcctattttc 3055501 aggcagtgac gccgagaacc gcagggttca attctctaga ttttggaagc atgagagaag 3055561 gaacaattgt atttacttta ttattgatgt ttatcggagc aggaagcgca tcaacggcga 3055621 gcggcattaa gctgactacg ttcatcgtga ttttaacatc tgttattgct tacttgagag 3055681 gtaaaaaaga aacggttatt ttccgccgtt ccatcaaata tccgattatc attaaagctt 3055741 tagctgtgag cgtcaccagt ttgttcatcg tgtttttagg gattttcgcc ctgacgatca 3055801 cagaacaagc gccatttctt caaattgtgt ttgaaacctt ttccgcattc ggaactgtcg 3055861 gccttacgat ggggcttact cctgaactga caacagctgg caagtgtatc atcattgtca 3055921 tcatgtttat cggaagaatt ggtcctttaa cgttcgtgtt ttcattcgca aaaacagagc 3055981 aatcaaatat ccgttatcct gatggcgaag tgtttacagg gtgatatcaa aaaaatccgg 3056041 cgtgcagtcg ccggattttt tatgattcga tatgagattg attttgtctt ttttcctgtt 3056101 ccgcgatgat ttcgttatcc tccgcgttat cacgggtcac tttttgcgta agaatcgcac 3056161 caactgctac aagtatcata acagcgatgt aataaccttt ttcattgagt tccagattat 3056221 cagcattata gagtccgata ctaaacaaaa atactcccgc aaaaaaagta aaataagcta 3056281 gtactgtaaa ggcaaccgtg tttctgcgtc tatatttctg cacctttgtt ccctcccgaa 3056341 agcatagtta aaaagtgata acttccgtgg aatattatac ctcaaattcc ccggaatgga 3056401 acaaagaatt aaaaatacca gtaaaaaggg cttaggttgc ctcctttatt tcaacagctg 3056461 aatcatcaat ccagccgata agtttatcat tgatttggaa ttggtaccat acagactggc 3056521 ctttctgttt tttagacaca acctttatgt ctttgccgac gtaagattgg gcagaggtaa 3056581 gccttatgga ccgatcatca gtagaaggct tggaccatac gtcttgaacg gcactgtctt 3056641 taatagaggc gtttaaatcc acagatttga gggatggatt tacctcatcg tactcatcta 3056701 aatcgtattt ttccacaata gcgctgattt tgtcagcgta gtcagggtct gtagcatatc 3056761 ctgatgtttg cagggcggtt gccgcttcct tataattccc tgcctcaagc accggtttat 3056821 acttcttttt attccacgat gtgccacgga cgaacaattg ggcgtgatca tccatagatt 3056881 caaaaaacgt gctgtatttt cgaaacttcg cgcgaatggt ttttcttttc cctttttcaa 3056941 cttcgtccgt ttccatcgtg acatgatggc ctttataatt cccttttacg ccaaaaaggt 3057001 tgttggcctt agcagccagt tcactgttcc cccagtccga ttcgagaatg gcctgagcaa 3057061 ttgtgatgct ggggagaaca tggtattttt catacaaaat ttgggcatgt ccggacagac 3057121 tgtctataaa tacttgctgt tcatcgattt cttcagtttc tttggatatt tcaatcggtt 3057181 ttgataaagt tgtcgctaaa acaaacagag ctagcggaat cgatacaagg aaaaatagtg 3057241 aaatcaagag tttacgtttt ttaagttttt tacgggccat gaaaaccttc cttcgaatta 3057301 aaagattacg aatgtaaaag aatctacctt ttagaatttt acttgcactt ctaatatttt 3057361 tcaattcttt agggataaag ttgggaaaag attgcaaaat aaaaaccttt tcgctcaatg 3057421 aaaaggtttt taccatgttt ctatttttgt aaatttctga gtgcattccg atattccgta 3057481 tcatttatta ctttatatga tttgacagtt gccttcgaca aaccttgtgc tgagacggcc 3057541 ggtttttccg gagctgtttt cgctttatca tgtggtttat gtgccagctt gtgccccatt 3057601 ccagtggcat tcatacaaaa tgacaggcag acgagcagca cgctaaggat aaaagaaatg 3057661 aagaagagat catgataagc agtcatcata gaatcctgta ccgaaccgct ttgtctggca 3057721 gcatcttttt tcgtgaaaaa gccgatgaga atgggaactc ccatatagac aaacaatctt 3057781 aaaaactgaa cagctgtcat tctcttgacc aaatcaggca gcgggcctcc catggcagct 3057841 cccatcagcc ctgcggcgac tgtcaggcct gttcccgctg caagcatgat aaacagtgcc 3057901 gcgaacatat aaagagatga tcgatcctgt atatgcagcc attgaaaatt cacaaaaacg 3057961 agaatgagtc cgccgataat accgagcatc cctggtccga ctttatcgta taacagagcg 3058021 ctcaaaatgg ccgcgatcgc cactccgatt aaaagagtca agcttaaaag aatgagatgc 3058081 tcctgagaaa tatcatacat ttgacggagc aagccttgaa aagcagaaag gctgacagct 3058141 accgttatcg tccctgcagc tatgatcaat aagccgagca ccggttttgg cagcagcatc 3058201 agtttaatag atatgaaggg gtttttcact ttatattcca caatcaatag accaatgagc 3058261 aaacataacg tcaccccgaa accaatccat acataacccg atgacagccc ccatttttgc 3058321 agaaaaatga atgaaaccgc tgaggctgcg gcaaggaaga cagataaaag aattcccgca 3058381 cgatcaagcg gctgttcttg atccgccgct ccgtgatgct catcatgaag aaagaaatag 3058441 ctcaccgcga caccgatcag ggacaaggtg ccaaagatga aaaacagcca tctccaatgc 3058501 ccgcagcttg ttgcaatggt tcccaggatt gtaccgatga taacagaacc atagaatccc 3058561 ccgatcagca caagcagtgc atagttcctg cgttcaatcg ggaatgacag tacaagcatt 3058621 ggaatcataa tcatcagcat gacgcctgtt gccgcccctt gtaaaaagcg ccctgccgcc 3058681 atcaatgcaa tatcgcctga acatgcgatg agcagtgagc ctagtataaa gacaggtaat 3058741 gaagccagat agacgggacg agcaccgaat tttttcctca gcagcggtcc tgccggaact 3058801 aacaaggcaa aggccatatt gccgatcaat atcggattta ctgatgtaaa gacacttgtt 3058861 ccaaccgttt tctgaacaag gccttgaact gacgacaatg ccgtgttaga catcaatccc 3058921 ggcccgaccg ctaagacggc gagcaaagaa atcacccaat agtgttttgt cttcatgttg 3058981 tcatcccttc ctatatgaat acatgcgaaa cacatcattt tttgaaaaca aaagaagcta 3059041 atagattttg cataccatta gctttcattc taatattctc cctttcaggg gaaatgatat 3059101 tattttatta taattatgtg aatgaatgag catataatca aatattattt caaatcgatt 3059161 gtgttttgtc aatggagtaa atttcaagca caacatagaa agcttgaaag cttttccccg 3059221 atattgtgtc tagaactgca cttatgaatc cctgctcgtt ccctcaagcg aattaaagca 3059281 ggccgtttta atcctttcaa tccactattc caactaataa actcaaataa gttggtgata 3059341 agacaacatt ttacccccac atttttttgt gttcactggg cgtttgccgc ctctaaattg 3059401 tatatgggta aataccatga attaacctat gaaataccaa tgtaagggag gcaaaaacga 3059461 atggaactgt atgagtgtat ccaagacatt tttggcggct tgaaaaatcc atcggttaaa 3059521 gatttagcaa cgtctttaaa acaaattcca aacgcagcaa aattgagtca accgtatatt 3059581 aaggaaccag accagtacgc ttacggccga aatgccatct atcgaaataa tgaattggaa 3059641 attatcgtga ttaacattcc gccaaacaag gagacaacag tacacgatca tggtcaatcc 3059701 attggttgtg caatggtgtt agaaggaaag cttcttaatt ctatttatcg ttcaaccggc 3059761 gaacacgcag aactctccaa ttcatacttt gtccacgaag gagaatgcct tatttcaacc 3059821 aaaggtttaa ttcacaaaat gtccaatcca acatctgaac gaatggtgtc tcttcatgtc 3059881 tactcccctc ctttggaaga catgacggtc tttgaggaac aaaaggaggt attggaaaat 3059941 tcatgattga cagataaact gctcactttg acttcactca actggaggat tcagagaatg 3060001 aaaccttttc ctcaaaacaa aaaaaccctt atcgaataag ggtttaaagg tatggagcca 3060061 agggggctcg aacccctgac ctctacgctg ccagcgtagc gctctcccag ctgagctatg 3060121 gccccgtatg taacgtcatg tttattatag atgattttat tttgaaaaac aagctgtttc 3060181 ctcttgaatt gacagaaaaa ataaggctcg gaaaagagcc ttatttttcg acttacatca 3060241 tgatcaaaag taaaatcaca ccgagaataa ttcgatagat tgcaaatggg acaagtttga 3060301 ttttgttaat cagccttaag aagaaacgga cgacaaacag tgcgaccaca aaggcacaga 3060361 taaagccgac gatgaaaaac ggcatcagat ccgaacttaa gctgtcccaa tgcttcacga 3060421 ggcttagaaa gctggctccc atcatgatcg gcatcgccat aataaacgta aagtcggctg 3060481 cagctcggtg gtttaatccg agaataacac cgccggaaat ggttgaaccc gaacgcgaga 3060541 aaccaggcca aagggaaaga cattggaata agccgacggc tatcgcctgt ttataggaaa 3060601 tgcggtcgag tgtgtctgtc gctgttttcc gtttattgac ccagtcagca aaaagcatga 3060661 ggattgcccc ggcaattaaa ccgatggcca cagttttaac ggaaaataaa tattcatcaa 3060721 tgtaatcttc aaacaaaaag ccgagaacag ctgcaggcac gagtccgacg gcaatttggg 3060781 caatgcttaa tttatgtccc tgctcctggt cgcttgtaat attttttttc aagcccagta 3060841 aatttaaaat tcggtcttta aacacgatag ctactgctaa aatggagcct agctgaataa 3060901 ccaccttgaa tgagttagca gcttcttctg acatcagatt acttgatttt agccagatgt 3060961 cgtctactat gatcatatgt cctgtcgaag aaaccggcgc gtactctgtt aatccttcta 3061021 cgattcctaa aatggcggct acaaacaatt cccatagagt catgattttg attctcccca 3061081 ttagacattt atttttttac ataacgggag cttcccataa atggaaagcc cgtcttatat 3061141 aactataaac gaaaatcaca ctttatgccc cggcgtattt tcattttttt cttcatcgta 3061201 taaatgtgac tgcattttaa accagtcaaa taaatgtgtc gtaatgactt tggcaaccgc 3061261 atagccggga atcgcaagaa tgattccaac aacgccaaac agcttgccgg ctgttaacag 3061321 cagaaaaata atcgtaatcg gatggatgtg aaggtttttt cccataattt gcggagagat 3061381 cagcttccct tcaatcagct gaacaatcgt ccaaacgatc accagcttaa gcagcatgag 3061441 cggcgatgtc actatggcaa tgataatcgc aggcgtaatg gcaatcgttg gccctaaata 3061501 tggaacgatg cttgtgcaag ccgcaatgac tgcaagcaat gaagcataat ccagcccgat 3061561 aatcaaataa ccgataaaca gcaaaaaccc gatacagaag ctgacaatga tctggcctct 3061621 gatataagag cttaaccgat gattcatttc gcttaagact gtatatgtct gttctttcaa 3061681 tcgagtcggc acaaacttca gtatgtagac cggtaatttt cttccgtctt ttagcaaata 3061741 aaatagaata aacggaaccg tgacgatcga aatgataatc tcagtcagtg cgccgataaa 3061801 attcccaaca ccggtaaagg tgctgttcac gatcgtcgct gcctgatccg aaacctttgt 3061861 agcaagatca gatatattaa tgttcatcgt ttgctgggcc tgattgacga agttgctgcc 3061921 aatcagctgt ttcgtctgat tttctacgac gtccacatat ctcgggatat tgtcaatcaa 3061981 actcataatt tgttctttta agaagggaat gatcgacacg atcgtgatcg tgatcagccc 3062041 gataaccaat aggtatagca gcaatataga atagattctt cttattcttc ttctctccag 3062101 aaaatcgacg actgggttta acagataaaa aacaatgcct gtcaaaataa tcggaagtga 3062161 tatcgttttg agcagaacaa taatcggggt gaaaataaat gatgtttttg taaatactag 3062221 aatatttaaa ccaatcagca gcagcacaag caaaaataaa acaaacttat tatccaagaa 3062281 gaatcgcttg aatctgccgc tccatgtttg caacgtctcc actatcgttc ctccgtcata 3062341 catagtttaa ttaaattgta cactatcgtc cctataatga aaaataaaaa ccgttaattg 3062401 ctggaaaagc tttctcggtt ttaacattct atttatatct atcatgtgat tttgttcttt 3062461 ttaagctata atttagctat atcatgcaaa aggagcgata cgagtgatac gttttgcaat 3062521 aataggaacc aactggatta cagaccgctt tcttgagtca gcagcggata tcgaagattt 3062581 tcagctgact gctgtttatt caagatcggc tgaacgcgct ggcgagtttg ctgctaaaca 3062641 caacgctgcg catgccttct cagaccttca ggaaatggcg gcgagcgatt gctttgatgc 3062701 cgtatacata gcgagcccga acgctcttca caaggaacaa gccgttctct ttatgaacca 3062761 tggcaagcat gtgctttgtg agaagccgtt tgcttcgaat acaaaagaaa cagaagagat 3062821 gatctcagcg gctaaggcaa acggcgttgt tctcatggaa gcaatgaaga ccactttcct 3062881 gccgaatttc aaagaactga aaaaacacct gcataaaatc ggcactgtcc gcagatttac 3062941 cgcaagctac tgccagtatt cctcacgata tgacgcgttc agaagcggaa ctgttttgaa 3063001 tgcgtttcag cctgagcttt ccaatgggtc attaatggat attggcgtct attgtattta 3063061 tccggctgtt gtgttgtttg gcgcgccgaa ggatgtaaaa gcaaacggat atgctttatc 3063121 ctccggagtg gacggagaag gaactgtcat tctgtcttac gacgggttcg aagctgttct 3063181 gatgcattcc aaaatctcta cttcctatgc cccggctgaa atccagggtg aagacgggac 3063241 gattgtaatc gatacgattc accggcctga acgtgttgaa atccgctacc gggacggccg 3063301 ccttgaaaac atcgcgatcc ctgatcctaa accggcgatg ttctatgaag cagaagaatt 3063361 tgtcacgctt ataaaagaga ataagctgga atctgaagaa aatacatttg aacggtcttt 3063421 gaccaccgca aaaattatgg aagaagcaag aaagcaaatg gggattgtat accctgctga 3063481 tcaagcttaa aaaaatccgc ccgcgtgcaa atgccgcggc ggatttttta ttagacaatc 3063541 ggagaagatg ccttcctttt taaaagcacc tgttgctcat attctttgat gtcataaagc 3063601 catgcctctt ttaccggaac gcccatttgc tcacagtagg aatcccagat ggctccgaaa 3063661 ggatatgttt tgaattcctc catcagggcc agcctttctg tatagcggcc ctcttcctgc 3063721 aattgtttta aatatccgtt cgggagaagc agggcataca ataaagcttt gatcatattt 3063781 ctcgttccga tggtccaggc ggctacacgg ttaatgctgg catcgaaaaa atccagaccg 3063841 atggctacct tctcaagagc atgatttcgt acaatttcaa gagcgatttc tctcaattca 3063901 tcatccaaaa ccactacatg gtcgctatcc caacgaacag gccgcgatac gtgcaaggca 3063961 agcttgtctg tgtaaagcag catggacgag atcttgtttg ataccgtctc agtcggatgg 3064021 aaatggcctg tatcaagtaa acaaagctta tgattcgtca aagcataagc taaataaaat 3064081 tcatgagatc cgacaacata tgattcggag ccaagcccga acagcttgct ctcgattgaa 3064141 tcaagattat gttgttcact gatctcctct gagaagatcc gatccagtga ttcttttagt 3064201 cttttacgcg gtgtcagcct atcactcggg atatccttat agccgtcggg aatccaaata 3064261 ttcgtcaagc aaggtgttcc taattctttc ccgaagtatt ccccgatacg gcggcaagcg 3064321 atgcaatgcc tgatccaaaa ttctctgatg tccggatcag ggtgtgaaag ggtgagtccg 3064381 tcagccgctt tctcatgcga aaacaaggtt ggattaaaat ctaaaccgag accaaggttt 3064441 tttgcccatt tcacccagtt ttcaaaatgc tgcggcttca attcgtcacg ttctaccgct 3064501 tccctgtttg tttctgcgta tatcgcatgc aggtttacgc ggtgctttcc aggaatgaga 3064561 gaaagagcct tctccaaatc tcttcttaat tcttcaggag tttgcgcttt tccgggataa 3064621 ttgccggtca cgtcaattcc gcctgaaagc tcgcccttat ttacttcaaa gccttcaatg 3064681 tcgtcaccct gccagcagtg gatcgaaatg ggcacttgct ctaattgccg aagcgcctct 3064741 tcaacatcaa ttccccattt ttcatatgcc tgttttgcac tgtcataatt ggcttttatg 3064801 gtcatacggc tctctccctt tatcagtttt tcaatccaaa taaaaaactt cctttagatc 3064861 tatcgcaaca ggactgaaat ccgaatttgt tttcattaat ggcgccatcg atttccacca 3064921 tctttggcaa acttccgtgt ccgccatctt tctccatttc tcttcatcct ctatttctaa 3064981 atatgcaaaa agcctgcctg tttcctcgtc tagaaaaatg gaataatggt gtgctccatg 3065041 agctttgagt gcttctgcca tctcaggcca aatgtcatca tgccgctgtt tgtattcttc 3065101 gtacttgtct tgatggacaa acatgatact ggcttttctt ttcaaacctt ttcacctctt 3065161 catcatttag atagcgcttt caaaacagtt tgctgaaatg actgaatgat cgtgcttcta 3065221 tcaatgtctt taggtgtaaa cactttgatc ggaaaggaat ttctgacgac ttgccgggct 3065281 tcttttatgt ctttgacttc tttggcagca atcatttgca tcaaaagatt tccggtggca 3065341 gttgcctcta tcggccctgc atataccgct tttccactca tgtctgccgt taattgattt 3065401 aagaaatcat tccgggctcc gccgccgatg atatgaaatt gctcgatcgg tttttctgtg 3065461 attgtttcga gctctttgat ggctatcgca tagatgatgg ctaaattgct gtagatgcag 3065521 caggcaagtt cgcctgcagt acggggaatc ttttggcggg tttgtctgca ataatgttgt 3065581 atttccttta tcatgttttc tggattcagg aaacgtttat catttaagtt tataaattgc 3065641 tggaatggtt ctgttttttt ggcttcttct gcaagctgct gaaaagaata atctgcttgt 3065701 agctgctgtt tgacttcttg tatcacccac atgccgataa tgtttttgag aaagcgaatg 3065761 gtgttgtttg cgccgcgttc atttgtatag ttgttttcta aagcaagatc agttattatc 3065821 ggtgttttgt tttcaacccc gattaacgac catgttccgc tgctgatata cgcccagcca 3065881 tcatttacgc ctggcgccgc aatgacggcc gaggccgtat catgtgttgc gactgtcatc 3065941 accttgcacg ccgggagatc ataatccggg aaccactcat ttcttagctt cccgagttca 3066001 caccccggtt cagtgagcgg cgcaaattgc tgttccagaa cagacacggc ttcaagcaat 3066061 tcaggatcaa gatttcccgt tgagacgttt aaaagctgtg ttgtggacac gtttgtgatt 3066121 tccgttacag cttttccggt taaacaatag cctaaataat caggaatcat cataattttg 3066181 tctgtctttt tcagcagctc acggtcttct tcaaacaatt gatagatcgt gttgaaaggc 3066241 tgaaattgta ttcctgtttt ttgataaatt gcggcttttg agagggtatg ttccagtttg 3066301 tctattgtgt gatctgttct tctatcacgg taggagattg cttcccgcaa ccgatcgcct 3066361 ttttcgtcca gtaagacata atcgactgcc catgtatcaa tgcctacggt gcagtgttca 3066421 tacccaagcg tctttacttt ttgcagtcct tgcaggattt gttttagcaa atgatcaata 3066481 tcccataagc aatgcccgtc tctttgactg aaaccgttag cgaacctgtg aatctcttgt 3066541 atgtcaagct tcccttcatt cagttcacct accatgattc tcccgcttga tgcgcctaca 3066601 tcaatggcag tataaatcat cctttcaccc tctcttcgaa agaggaacag ctgtcacctt 3066661 cacctttttg tcctcaagag cttttaccga tgccggatca agtccagaat ccgtaataag 3066721 gcggctgaca tcttgcagcg aggcgatatg tgaaaactcg cggttccccc atttgcttga 3066781 atcggccatc aaaatggtct ggtccgacct ttcgatcatc cgttttttga gcagcgcctg 3066841 ccactcattt gaatcactca tcccgttgtg tacgtcaaat cccttacatg acagaaaggt 3066901 tttattgaca tgataggtct caagtgaacg ctctgctaac gggccggcaa atgataatga 3066961 tttttccagc aaaatgccgc ctgttgaaat gactgatatg ttttctttat tgctgagttc 3067021 aatagctgct ttcattgagt ttgtaatcac ggtgagctca atgtcaggga gtatttttgc 3067081 catgtaccaa gcggttgtgc ttgcatcgag aatgattcgg tctccgcttt ttacatattt 3067141 ggccgcttcg tgagcgatgg cttttttttc gatgacattc gtgatttccc gttcagaaaa 3067201 atgaatttct gattccttct gctgaatact gaccgctcct ccgtggctcc ggctcagttt 3067261 atgttctttt tcaagctttt caagatcacg ccgaatggtt tcctctgtga ctgaaaaaat 3067321 gtcacttaat tcggaaacgc ggatgcttga acgcatattt actatttcca ctattttttg 3067381 ctgccgttct gctactagca tcggtaacgc ccttcctcat atcgtagtcc gtcttatatt 3067441 tttatcatag catatatcta acgcgtaaaa gcagcaggga cgccgccgtc taccgtgatc 3067501 atgcagcccg ttgttttttc ggctttggaa gaagcgaaga atgcaatggc ttcggcaata 3067561 tcctccgggt aaatattgac gagcaatgct gtccgtttcc ggtaatgttc ctccagctga 3067621 tccggttcaa tcccgtacgc cgcggctcgt tcctcacgcc agcttgaacc ccagattgcc 3067681 gatccttgaa gaactgcatc aggcaaaacg gagttgaccc taatgccgaa ttctccgcct 3067741 tctgctgcga tgcatcttgc taaatgggtt tcaagcgcct taacagagct gtaggcagag 3067801 gcgttttttc ccgcataaac tgaatttttc gatccgacaa ataccatgct tccgcctcta 3067861 ttttgatgtt tcatctgttt aaacgcttca cgggctacaa ggaaatagcc tgttcctaaa 3067921 acattcatat taagattcca ttcttttaga cttgtttcgt caaatgggct tgatgtggcc 3067981 agcccggcat tattgacgac gatatcaatg ccgccgtaag caagcgccgc tcgttcaaaa 3068041 gctgactgta cgtcttcctc ctttgtcaca tccattttga cagccattgc ccgtcctttt 3068101 ccgtatgcat cgtttatttc cccggcaatt ttctgtgcgc cttctatatt cagatcagct 3068161 acgatcacgt gccctccctc agctgcaaat cggcggcatg ccgcactgcc gattccgccg 3068221 gctcctccag ttatcagcgc tacttttcgg gaaaattctg cttccggcgg ggccagcgtg 3068281 agtttatata gttcgagcgg ccaatattcg acatggtagg actcattttc atgtaaagaa 3068341 acaaattgcc ccagagcggt tgctcctttc attacggcga tggccctccg atataaagcc 3068401 ccgcttactt tagacatcgc ataacttttt cctgtattca ccattccgat tccaggaatc 3068461 aatatcaccc gcggggcgga ttcaaagatt tgatccccat cctgctgatt gcgtgtaaag 3068521 taagcctgat actctgatgt aaaggtctcg actcctgact tgatcagatc tgcaagcttg 3068581 tgcacatctt gagtttccgg attccaatca atgtacagcg gaacccgttt tgtgtgaaca 3068641 aggtgatccg ggcatgccgc accgatttgc gaaagtgctg gcgcttggac actgtttaca 3068701 aattccaaga catcgtcatg atcatcatag gaaaggatca ttttcttttc ttcacttact 3068761 gctcctctga tcacaggcat gatgcctgcc aagatttgtt ttcttttatc ctccggcagc 3068821 ggctgatacc ttttgcctcc gaatacctca tgctgattga tacgatcgtt aatatactgc 3068881 tcggcttctt gaatgatgga tatcgttttt tgataacatg tttcagacgt ctctccccaa 3068941 gtgactaagc cgtgtttctc cattaataca agctcggcgt gggggttgtt tgctacgcct 3069001 tcagcgatca ttttagacaa agtaaatcca ggacggacgt atggcaccca tacaaaccga 3069061 tttccgtaaa tgtcttcagc gatttgtttt ccattatccg cacagcatat gctgataatc 3069121 gcatctggat gggtatggtc aacatgtttg tatggcagaa aagcgtgtaa tagcgtttca 3069181 attgaagggc ggggatgttt gctgtctatc atacaatgag acaggtagtc taccatttct 3069241 tcatcgggca tttggtccct tttaatcagc gggcggatat catctaattt caaaccggaa 3069301 aagttatgcg ctttcattgt tgccaaatcc gatccgcttc cttttaccca catgacttct 3069361 atttcacggc ctctaaaatc cttttccgtt gttttcatag atgtattccc cccgccccag 3069421 ttgcagacag tgcggtctga cccgatcaga ttggacctgt acaccaattc ctctacacct 3069481 ttaggtagct gtgcagctcg ctctgaatcc catatatgtt tcaccatatt tgatattcct 3069541 ccataccctt ttatttgtat ccgttttcat tatatatgat ttctgtttgt ttttgaatcg 3069601 tttttgttta tttttgcttt ttaacaaaaa aagaaagcag cagatatgcc gctttctcgt 3069661 ttcattatga ttctatttta aatttcttcg taatgtcctg aagttcttcc gccatgtttg 3069721 ccaacgtttc cgctgaagag ctgatttctt ccatggacgc aagctgttct tccgccgaag 3069781 ctgcgatatc ctgaatgcct gctgagcttt ctttcgccac tgcagaaata tcttcaacag 3069841 cacttgacac ttcctgtgat ccggctgaca gttgttcaac cgtcgcgttc aagttttgca 3069901 attcgccgga aatttgggtt gtcatctcat agatttgttt aaagctttcc gctgtttgat 3069961 ccgtaatctg caagccttct ttcacttcat gattcacgga ttggaacatt gaaagtgagg 3070021 tgctgatttc cctgacaatc tcttgaatta atccttcaat ttccttggcg gagtctgctg 3070081 attgtacagc aagttttcta acctcttccg caactactga gaaacctctt ccgtattctc 3070141 ccgctcttgc cgcctcaatc gcagcattta atgcaagcag gttggtttga tcagcaatgc 3070201 cgttaatcac attcaagatg cttgtgatgt cttgcgattt tgtttcaagg cccttcacaa 3070261 ccgcttccgc tttttgaacg gattggtcaa ttgttttcat ctggccgact gtatgctcca 3070321 ccagcttttc tccgctgccc gctgcctcag aggactgaat cgatgatttc gtaatggttg 3070381 aagaggcttg agccactttt gaaatcccct cgttcatttg agaaagatga tttgagcttg 3070441 tttccagttt ctcgctttgt gcctcgttgc catctgagaa ctgttcgatg gcaagtgtaa 3070501 tatgttcagt tgccttgctt gtttgggctg cgcttgctgt cagctcctca gaagatgaag 3070561 cgacgttttc tacagacgtt tgaataacgc ctattacaga acgcaatgat gcagacattt 3070621 cattaaagct ttcgccaagc tggccaaact cgtttttcga gtgaatgtca atgacttctg 3070681 tgagatctcc gctgctgatt tttgcagacg ttgagacaag ttttcttaac ggcttggtga 3070741 tggcacggat aatatagagt atgagtatgc cgccgattac tattgacacg catagaatga 3070801 taaccgcagt gttcagcacc gggcttgaag catcttgcaa ttcactgaca aaatatgtgc 3070861 ccgcgatttt ccagccagtc agtttatttg tcgtaaaggc cattttcttt tctttgcctt 3070921 cgaatgtata ttcaaatgag ccttcttttt tggaatatac ttggtttgtc caatcgccgg 3070981 aaccggttgt ccccggctta atggtcggat gggcgatata ttttttgttg cctgtcgtaa 3071041 taaatgcaaa gccttctttt ccgattttga ttctttttga tgcagtaagc acttcatcca 3071101 ggtttaaatc tagcgctata acccctgaac cgtcttttaa ttgttttgaa attgtgacaa 3071161 cgatatctcc tgtcgcttca tcggtatacg gttctgagaa aacagcttgt cctttttccg 3071221 caaccgcctg tttgtaccag tcacgtcctg tcggatcgaa acctttcgga acaccgctat 3071281 ccggatattt ataaagcttc ttatcttctg aggcagcata gattgcgcct acatcgtcgt 3071341 taagtgtcgt gtactgctta aatttctctt tcagtaatgt tttgtttttg cctaacaata 3071401 tgtctttatc gactgtctca ctataataat ctattgcttt tactttatct tctaatttat 3071461 tttgcagcgt actgtttagt tcttcaacat ttcccttcgc actgcttatg agctctctgt 3071521 ctaacgcgtt ccaagctgat tgataactga aatatgctaa aaccccaacc ggcaaaataa 3071581 gcactgccag aaacgcagcg attagcggtt tgctgatcga tggctgtttg atccattgta 3071641 tgaattttcc cattctcgtt gactcctcct ttaagataaa tctaatatcg tcaaactagg 3071701 ataaaaggtt taataaaaaa actaaaaaaa acacccaagc gcaacaagct tgggtgttaa 3071761 ggcttattat tcaattttaa atcgtttggt catatcccga agctcttccg ccatagagga 3071821 aagggtctct gcagacgagc tgatttcttc catggaagct agctgctctt cagctgacgc 3071881 cgcgatatct tgtatatgcg ctgagctttc ttttgaaatc gatgcaatgt gctcagacgc 3071941 tcccgaaact tcttcggagc tggcagaaag ctgctgaacc gtcgcactca tattttgcag 3072001 ttcgccggcg atttggttcg tcatttcaga aatgcgtttg aagctcattt ctgttttatc 3072061 tgtgatgtca agtcctgtct gcacctcttg attgacagat tggaacatgc cgagtgatgt 3072121 attgatttcc ttcacaattt cgatgattaa tccttcaatc tcttttgctg aatctgctga 3072181 ctgtactgcc agttttctta cttcttccgc tacaacggag aagccgcggc cgtactcgcc 3072241 tgcgcgcgct gcttcaattg ctgcgtttaa ggcaagcagg ttcgtctggt ctgcgatgcc 3072301 gttgatcaca cgcaaaatgt ttgtaatatc tttcgatttc gtttccaatc cgcgtacgac 3072361 ttgctccgct tctttaacgg acttgtcaat gacattcatt tggccgacgg tttgatgaac 3072421 aagcttgccg ccttcacttg caatttctgt cgattgaaca gatgaatcag tgatcacttc 3072481 agaagcttga gccatattcg tcaacccgtc attcatttga taaatgtgct ctgctgccgt 3072541 ttcaatgttt tcgttttgtt tttcattgcc gttagaaaat tgttcaatcg ccaatgtaat 3072601 gtgctctgtt gccttgctcg tttgcgcagc tgatgcagtc agctcctcag aggaagcggc 3072661 aacattgtct accgaatcct ggatggcgtg tatgagagaa cgaagtgacg acgccatatt 3072721 gttaaagctt ttgccgagct cgcccaattc atcttttgaa cggatatcaa tggtttccgt 3072781 caaatctccc tcgctgatcc gcttagagga accgacaagc tgtttcagcg gtgttgtaat 3072841 cgaccgaatg atcaatgtca tgacgataat ccctatgata atagctgcgg ccaagacaat 3072901 taaagcaagg tgaaggacag gctgggctgc ctcatggatt tcatccaaat acatggtgcc 3072961 gccgatcttc catcccgtca acttgtttgt gtcaaaggcc atttttttct tatcgccatc 3073021 catggtgtat tgaaaatcgc ctttatcagc actcaacatc ttatcgagcc agtcgccttt 3073081 taattcagtt cctgattgtt cattagggtg tgcgacaact tttttgtcct tcgtcatgat 3073141 aaatgcgtag ccttgtgtgc cgatgttgac ttttttggtt gttttcagca gattttcaat 3073201 cgtcatgttg attgcgataa cgcctgaacc atcttttgtc tgctgggcga ttgtcacaac 3073261 catcgtattt gtcgacgcgg ttttataagg gtctgtgatc acgactttcc ctttatttgc 3073321 aaccgctttt ttgtaccagt cgcgttcaac cggattatag ccgcttggca tcggaagatc 3073381 cggatagcgg gtaaagtgcc cttttgtgtc acttgtataa atggattcta catccttgtt 3073441 aatgctgata tattgtgaga atttctctgc aatgcttgca ttgctttttg cattgtattt 3073501 ctcttttgtc agccattcgc tgaaataatc agcactgttt tctttttcgc cgatgctggt 3073561 gttaatgatt tcgtttaatt gctgtacatt ttccaatgcg ctccccatca tctgtctgtc 3073621 gagtgagctg ctagccgatt gatacgcaaa gatcgccaat atgacaaccg gtatgatgag 3073681 gatcgacaga aaggaaacga gaagcttccg tgtaattgat ctttgtttta tgagttggag 3073741 tatttttttc atcattcatt tctccttttt tatgctaccc ttcatatcgg ctggaaatgg 3073801 gtaaatatat acagcaaaaa agaagaaatt taacaaaagt aactaatttc ccataaataa 3073861 atagtatttt agacctatta tttgtctact ttaaattgtt ttgtcagatc acggagttct 3073921 tcagacattc tttcaagcgt cagtgcagat gaactaatct cctccatgga tgccagctgt 3073981 tcctcagctg aagcggcgat atcttggatg ccatccgagc tttccttaga aatggcagtg 3074041 atatcatttg aagctgcgga aatttcttga gctcccgctg acagctcctc aaccgtcgca 3074101 ttcatgtttt gcagctcgga agcaatttga ttggtcattt gcgatatatg tttgaagctc 3074161 tgtttagttt catccgtcat gacaagccct gtttcaactt ctttgtttac ggactgaagc 3074221 acgttcagtg atgtgtgaat ttcttttact atttcactga tcagcgattc aatttctttt 3074281 gctgagtcag ccgactgtac cgcgagcttt ctcacttcct cagcgacgac tgagaagccc 3074341 cggccgtatt cacccgctct ggcagcttca atggcggcat ttaaagccaa aagattggtt 3074401 tgatccgcaa tgccgttgat gacacgcaaa atattcgtga tatcctttga tttgatctcc 3074461 agccctttca ccacttgttc cgctgctttt acggaatggt caattgtgtt catttggccg 3074521 gctgttttct ggacgagtgt ctcccctttg cttgacactt cggttgaatc tgcggatgtt 3074581 tctgtaatca ctgctgcagc ccgcgccagc tctgccaatc cgtcattcat ttcattaatt 3074641 tgttcggttg tcgtttctat tttctcgctt tggctttcac tgccgtttga aaattgctcg 3074701 atagccatcg taatgtgctc agtggctctg cttgtctggt ctgccgatgc agtcagctct 3074761 tcagacgagg aggcaacgtg ttctactgag tctttgatcc cgtgaatgag cgagcgaagc 3074821 gagtgtgcca tatgattgaa gctctcactc agaacgccga gttcatcttt tgaattgatt 3074881 tcaatcgttt cggttagatc gccttcacta attttttcag cggatgcgac aatgcgtctc 3074941 aatggctttg tgatggatcg aatcacaaaa taaatcgccg tcattccagc tccgatggca 3075001 atcgccagaa cgattgaagc catgatcaga accctgcttg cagcatcgtg aatctcgttt 3075061 gcatacatcg tgccgctgat tttccagcct gttgtttggc ttgttgcaaa tgccattttt 3075121 ttctttttgc ctttgtacgt atattcaaag tccccgcttt tatccttgta gagcttatca 3075181 acccagtccc cttttagctc tgttcccgct ttttctccgg agtaggcgat gactttcttg 3075241 ttttggctca aaataaaagc atagccttct tttccgatat tgattccttt cgcggtagtg 3075301 actaagtcat caattttcat atcaatggcg acaacgcctg acccatccac cgtttgacgg 3075361 gcgatggtga cgaccatttt tcctgatgaa atcgattcat aaggctcagt gacaattgtt 3075421 ttgcctttat tggccattgc ttctttgtac caatctcgtt ccaaagcatt aaagtcgctt 3075481 ggcatgtcag cgtacggata acgtgtgaag tccccgtctt tgccgcttga aaataccgca 3075541 gcgacattat cattcatttg gataaattgt ttaaattcct gtttcagctc tgttttcttt 3075601 ttatcctgaa atttttctgc tgtagcccaa tcgctgaaat atgcgaggct tttttcagta 3075661 gtgctgattt tatcatcaat gatgtgatct aatatctgaa cattttcctt tgcgctttgc 3075721 gtcatctgta catcaagtga ggcaactgct gattgataag cgctaaccga aagggcggtt 3075781 atcggaacaa ttaagatcag caggaaagaa ataataagtc tccttgcaat tgatgatctg 3075841 cgaatagtgg tgagtgtttt tttcatttcc ttttgaacct tctttcaata atttacaaat 3075901 tatatcggcg gatcttcctt taaattacat tgaaaatgga ggaaaaaatg aaaaatagtt 3075961 ctaaattcac ctgttaaact aggactttat tattgtttac catataaaaa aacagcgctt 3076021 tgatagcgct gtttttcggt ttttactcga ttttaaattg tttcgtcaga tcgcgaagct 3076081 cttctgccat ctgcgcaaga gtcgtcgctg aggaactgat ttcttccatg gaagcaagct 3076141 gttcttcagc tgatgcggca atgtcctgga tgcttgccga gctttctttc gacacgtctg 3076201 caatgccgct gactgctgct gaaacatgct gtgaacggtc tgacagctgc tcgacggtgg 3076261 aattcatcgt ctgcagcttg cccgcgattt cgtttgtcat gctgaaaatg ctctggaagc 3076321 tttcttttgt attgtctgtg acaacaagtc cggactgtac ttcctgattg acctctttaa 3076381 acatgtgaag agaggtgtcg atttctgcga cgatttcttg gatcagcttt tcgatttctt 3076441 tcgctgaatc ggctgattgg acagccagct tgcgcacctc ctccgctacg acagagaagc 3076501 cgcgtcctga ctctccggca cgcgccgctt caatggctgc atttagtgca agcagatttg 3076561 tttggtcagc gattccgttg atgactctca aaatgcttgt gatgtctttt gattttcctt 3076621 ctaagccttt gacaacagct tcagcctgct gaacagattg attaatcgag ttcatttgtc 3076681 cgactgtctg ctgcacaaac ttctcacccg ttccggcgat ttccgttgat tggatagatg 3076741 cctttgtaat atctgacgat gtttgtgaga cttgctggag tccttcattc attaagttca 3076801 gctgatgaga gctggattca accttttcgc tttgctcctc gtttccgttt gagaactgct 3076861 caatcgccat cgtaatatgc tcggtggctt tactcgtctg cccggcagat gcggtaagct 3076921 gttcggaaga tgcggccaca ttgttcaccg agtcctgaat agcgctgatc agagagcgga 3076981 gagattgtcc catttcattg aagctttccc caagctctcc aagctcatcc tttgaatgga 3077041 tttcgatcgt ttcggtcaga tcccccctgc tgatcgtttt cgatgattga acaagacgtt 3077101 ttaacggttt tgtaatcgaa cgaacgataa acagaattaa aattccgcct gccacaatgg 3077161 aagcaatcag cacaatcatt cctgttgtca gcacagactt tgaggcatcc ttaatttcat 3077221 ccatatacat tgtgccggct attttccaac cagtcagttc gtttgtagta taggtcatct 3077281 ttttatcttc gttattaaga gtatactgga gttcaccgct gtcattcgca tacattttgg 3077341 ctacccagtc gcctgaaagc ttttctccag ccttatggtt cttgtgggcg acataggttt 3077401 tgttttttgt tgcaatgaaa gcataacctt cttttccgac cttgatttgt ttcatttgtt 3077461 ctaacaattt atcaatggta atatccatgg cgacaacgcc agatccgtcc ttcagctcct 3077521 gtgcaatggt aatgaccatg cttccgtcac tcgcagccac gtaaggatct gtcacgacaa 3077581 tttcaccgcc ggccttcatc gcatcctggt accaaggccg ttgtctcggg tcgtatcctt 3077641 ccggcaattt ttcttttggc gcttgtacat aagtgccgtt atctgcgccc ccataaattc 3077701 tggctactcc ttgattaata gatacatatt gtgaaaattt agctttgatc tcttcttgat 3077761 ttgatttccc tttgaatgcg gatcttttaa gagattcact gaaaaaggtg actgctttcg 3077821 ctttttctcc cagatcattt gtaacagttg tattaaatgt atcgacactg tttttcgcat 3077881 ttcccataat ttcctgatcc agctttccgc tggcgcttcg gtaagagcta aattctaata 3077941 taagaatagg gataatgaga atcgcaataa atgagacgat taatttcttt gaaatagacg 3078001 gtttcttcag ccaattgata aaagtcttca tgtcacttgc tccttcaggt ttgatacagt 3078061 atatatcggc tgcttaaaaa agttttaaaa taaaaaatgg aagaagttct ttttggctgt 3078121 cttctgcctt tttaactttc attgcccaag ctctttgcat atcttataaa aaacaagggg 3078181 ggctaaacat gattattgta tcaggacaat tgctccgtcc ccaggatatt gaaaattggc 3078241 agattgatca agatctgaat ccgctcttaa aagagatgat tgagacgcct gttcagtttg 3078301 attatcattc aattgctgaa ctgatgtttg agcttaaact gcggatgaat attgtagcag 3078361 cggcaaagac gctgcacaaa agcggggcga agtttgccac ttttttaaaa acatacggga 3078421 atacaacgta ttggagggtt tcaccggagg gcgccttgga gctgaaatac agaatgccgc 3078481 cttcaaaagc gattcgggac attgcagaga acggcccgtt ttatgcgttt gaatgcgcaa 3078541 ccgcaatcgt tatcatttat tacttggcct taatcgatac aatcggagaa gataaattca 3078601 atgccagctt tgacagaatt attttatatg actggcatta tgagaaattg ccgatatata 3078661 cggaaacagg acaccacttt ttccttggag attgtttgta ttttaagaat cctgaatttg 3078721 atccgcaaaa ggcgcaatgg agaggcgaaa atgtgatact actgggggaa gataaatatt 3078781 ttgcccatgg tcttggaatc ttaaacggaa agcaaattat tgataagctg aattctttta 3078841 ggaaaaaagg agccttacag tcagcctacc ttctgtctca ggcgaccaga ctggatgttc 3078901 cgtctctttt ccgcatcgtc cgctaaaaag ccccatcgcc tattttccgg acgatggggt 3078961 ttcaaatgcc tttcgttttc gatagaaggg ggctgtgcca aaatattggt tcgcagccca 3079021 ctccattttt tcaaggtcat ttcttgtcac gattggatcc tggctgctcc atttgataaa 3079081 gcggacaaaa tagtagcctt tgataggaac cattgtaact tttgagtgag gccagccttc 3079141 aaatacaaac tcaattttcc ctcttttttt ataagaatat tgaagaatgt tcatatctgt 3079201 cacctcagtt tatcaagtta cgttcggcaa agctcggtac gtttacatcc attgattaac 3079261 tatccctcat gcaggctttc cggaaaacaa agggtgaggc gcgtgtctct ttccctcgct 3079321 ttttatttcg catatggacg aatgccaagc acgccttcat tcgataaagc cgcagcgtgg 3079381 gcgggtgtga caagccctcc ggctatcggc gcttgttcag cgatcatgct tttgtcataa 3079441 aaaacagcct attatcccat cattttgata tagcatgtcc gggtgcgagg cccgtcaaat 3079501 tcgcagaaat aaatgccctg ccacgttcca agaataagcc ggccgttttc cacaatgaca 3079561 tgctgtgaag ctccgaccgt actcgacttc atgtgtgcag ctgtattgcc ctccatatgg 3079621 cggtccagct catgttccca cggatatacc tcatcaaacc ttctgagcat atcttttttg 3079681 acgtccggat cggcattttc attaattgta atgcccgcag tcgtatgcgg acagtaaatc 3079741 agcgctgcgc cgctcgttat acctgtttct tgaagaaacg cttccacctc ccgggtgata 3079801 tctatcattt catctcgttt ggttgttttg atttgcagtg ttttcagcat ttgtttctcc 3079861 tttcgtttgt ccgctctcat cgcttaattc gttctgtgtt cttttttttc ctgttaaacc 3079921 gctctcataa acccgataaa acaaaaaaac tccagtctaa ggctggagtt tagcaccata 3079981 gatatattct tgcttcatac ggctttaaga gtactgatgt catatgcttg tgcggctctg 3080041 tttcaatatt tgacaagacg agtgcatctg atgacaatgg caatccagag tgcctgaaca 3080101 acgccggtgt tcctgtcaga ttggccgcaa tcagtgcagt atggctctcg tttttccgaa 3080161 gatatgcaaa gatttgctga tcttccggta aaatgagctc gtatgtcccg ttaataaaaa 3080221 catcatatgt ttggcgcagc ttgatcaagc ttttgtaaaa atggtaaacg gatgttttat 3080281 cgtttttttg cgcctcggca ttcagccatt tgtaattctc attgattccg atccacggtt 3080341 tggcctcaga aaatccggcg tatggaccag cattccattg catcggcgtt cgcgaattgt 3080401 ctcttccctt tttccagaca atcttcatca catcctcgtg tgatgtgcct ttcgctgttt 3080461 ttgtttcata caggcgtttc aatgcgacat catcatagtc ctcaatagat ggaaaagcca 3080521 cgttcgtcat cccgagttcc tgtccctgat aaataaacgg tgtgcctttc atgagaaaat 3080581 aaacagcgga aagcgctttt gcactttctt tcaggtacac tccgtcgtct ccccacacag 3080641 aaactgaacg gggctggtcg tgattctcca taaacaaagc attccagccg atcccttcca 3080701 gactgtcctg ccagtcagtt aaaattcgtt taaatgcaac gatatcaata ctttcattga 3080761 tctctacatc ccacaggccg agatgctcaa attgaaaaat catgctgaat atgccgtttt 3080821 tttctccagc ccaatcagct gcttcttttg cagcgacgcc gtttgcttca ccaactgtca 3080881 taatcggata gcgggaaaat gtgttttcct tcagctctgt taacaaatcc ataatgccgt 3080941 cagcattcat atgataagga aaggaaggga catagtccag tccctttgga ttcggcatgt 3081001 caggaaaccc ttcttttttc ttaatatgcg taatggcatc cacccgaaat ccgtcaattc 3081061 ctttatcaag ccaccaattg atcatgtcat aaacggcatt cctcaccttt tcattttccc 3081121 aattcaaatc aggctgtttt ttatcaaaaa ggtgcagata atactggctt gtcttttgat 3081181 catactccca agccggcccg ccgaaaatgc tttcccaatt gttgggcgtt tttccgtttt 3081241 tgccgtcttt ccaaatatac cagtcgcgct tttccgagtg tatggatgaa cgggattcta 3081301 tgaaccatgg atgttcgtcg cttgtgtggt tcacaacgag atccataatc agcttcatat 3081361 ccagatcatg aatgtcacca agcagctcat caaaatcttc catcgtgcca aactcgctta 3081421 atatgttttg ataatccctg atatcatagc cattatcggc attcggtgaa tcatacagcg 3081481 ggcaaatcca tatgacgtca gcgcccagct cttttatgta agaaagcttg gttctgattc 3081541 cttgaatatc cccgattccg tcgccatttg aatctttaaa actgcggggg taaatttggt 3081601 aaactacggc ttccttccac caagcctttt tcatacagcc actccttccc agtgtaccgt 3081661 tcttatatat cctatgtaga aaaaggtctt tacagcattg ctttttaaga aatgacttga 3081721 tgacacaaaa aacagccgtt tgttccccgg ctgtttttta tcaaaaatca gtttttttta 3081781 tttctacaaa acggatgtgg tgatcttcgg cgtcgaggat tttaaattca cagccctccg 3081841 cgtgtatcac atcccctgct ttcagctcca ttttttgcgt tagaagccag cctgcaatcg 3081901 tatcaatttc ttcattttca atcgcaatgt cgagaaggtc attcacttcg tctattagcg 3081961 cttttccatc catcacataa tggtgctcgc cctttttcag gatgtgcggt gtttcatcct 3082021 gatcatactc atcgcggatt tccccgacga tttcctcgat aatatcctct acagtgacaa 3082081 gccccgccgt tcccccgtat tcatcgacaa gaatcgccat gtgaatccgc tccttctgca 3082141 tgcggattaa aagctgctga acaggaatgc tttcaatgac tctgataacg ggcctcatga 3082201 tttgattcag ctttatcggc tggccgagaa aataagcttt aaacatatct ttgctgttga 3082261 tgatccctaa aatatgatcc ttgtcatctt tgatgacagg gtagcgtgta taccgttcat 3082321 taatgatgtg atgaattgcc tcttcaagcg actgctccag agagataacc gcaatttctg 3082381 tccgcggaat cataatctct ctcgctaccc ggttgtcaaa ttcaaaaatc ttatttacat 3082441 agcggaattc agactgattg atttctccct tttcatagct ttcagaaagg atcagcctta 3082501 gttcctcttc gctgatgaca acctgatgct cctttaccga atgaaagcca aacaatttca 3082561 caagaaaact tgcagagccg tttaatgctt taataaacgg gtacgtgatt ttataaaacc 3082621 agatcagcgg ctttgcaatc cataagctta cagcttcagc tttttgaata gaaaccgttt 3082681 tcggggcaag ctcccccatc accacatgca aaaaagtgac gatgataaat gcaactacaa 3082741 atgtgacaat gtggttaaac ggttccggta tgcctgtcat tgtaaataag ggatgaagaa 3082801 aacgttcaaa tgtaggttca ccaagccacc caaggccgag ggctgtaatc gtaatcccga 3082861 gctggcaggc tgataaatac tcgtcaagat tggagatgat tttatgtgcg gctagtgctc 3082921 ggctgtcacc gctttcgatg agctgattga tttttgaacc tctgattttg acgatcgcaa 3082981 attccgctgc aacgaaaaca gccgtaatgc caatcaaaac aaaaatggcg atcaattgta 3083041 aaataagcaa aaaaagccct taccataaat ggtaaggggc cacctcctta acgttaattc 3083101 tcatcacgac cgtttaagaa aatcatcaca aaacgaagta gttcaaacag ggaaaccagg 3083161 gcggcggcca catacgttaa ggcagcagca ctcagcactt tatttacccc attttcttca 3083221 ttgtttcgga tgaatccttc tgacacaata atctgcttcg cacgtgaact tgcattgaat 3083281 tcgacaggca atgtaatcag ctggaaaaag acagccgctg aaaacagtat gatgccaagc 3083341 ccgatcaaat tcaggctgcc gagaagcatg cctcctaaga aaagcaaagg agctacaccg 3083401 gatgcaaaat tcacgactgg gaagatttta tgtctcagca caagcgcacc atatgactcc 3083461 tgatgctgca aggcatgtcc gacttcatgg gaagctacgg atatggcgga aattgagcgg 3083521 ccgtaataga ccggctcaga taaacgcacc acccgtcttg tcgggtcgta atggtctgtt 3083581 aaagtgcctc ttaccggttc gaccggcacg tcgtaaagac cgtttatatc taaaatccgt 3083641 cttgccgttt ctgcccctgt acgtccgctt gaggcttcca cttttgaata tttttcaaag 3083701 ttgctcttta ctttaaattg tgcccaaaac gacaatccca atgcggctat tgttaaaaat 3083761 ataaacagca ttttttcatc atcctttgtt catgatcatt tctctattac gattatttta 3083821 atgagttttc tttctcgtgt acagaaatgc gctttttctt ccggcttgga gcacacaatc 3083881 caatcagcaa aaagaacagg cctgctgaaa acaaataaaa ggcgaaactg ccggccagtt 3083941 ctttcagaaa atgaagccag gagaagcttc cggaaaagtg attatatgaa ttcaaatcga 3084001 aaataaacaa aatcaccgcg gatgccgcca gctgcgtacc gattaaaacc acgatcgttc 3084061 tttgaaagat cgtcatcttt ttcatccttt ttgttttagt ttatggagaa atccggtttt 3084121 atatgttttg tacatttttt gaaaaacatc accggaagtg ggacatactg ttagaaaaaa 3084181 gcacgggtgt gatggaagct atgaaagtga cgagtgagga aaaggaacag ctgagcacag 3084241 caatcgaccg aatgaatgaa ggactggacg cgtttatcca gctgtataat gaatcggaaa 3084301 ttgatgaacc gcttattcag cttgatgatg atacagccga gttaatgaag caggcccgag 3084361 atatgtacgg ccaggaaaag ctaaatgaga aattaaatac aattattaaa cagattttat 3084421 ccatctcagt atctgaagaa ggagaaaaag aatgaaatca aatcggatat ttatttcatg 3084481 gctcaggtgg ccgttattta tccgaatcgg ggttattatt ttatgtctga ttcttttgtt 3084541 cggccaaatc atttatatac ttgagcctaa gcagttcact tcggtattcg aaggtatttg 3084601 gtgggctgtc gttacggttt ctacagtcgg ttatggagac tatgtgccgc acactccgct 3084661 gggacaggca gccggaatac tgctgatttt gagcggagca agctttgtca cagcgtattt 3084721 cgctacgtta tcagcggccg cattcagcag acagcatcgc tacattgaag gaaaagttgc 3084781 ttacaaaggc cgggaccaca tcattctgat cgggtggaat gaaaaaacaa accggctttt 3084841 gaaggacctt cagcttgccg ccccttccaa aacagtcgta ctaatcgatg aatccttaac 3084901 agaaggcccg cttattgaaa acgttcattt catacgcggg cacgctgccg atgatgggac 3084961 actgaaacgg gccaatatta ctgaagcgga atcagtgatg attactgccg atcagtataa 3085021 aagtgaaact gatgctgata tgctgtcagt gctgactctt ttatctgtta aaggtcttaa 3085081 tccccttgct tactgcatcg tcgagatttt aactgaccgt tttgtcacca atgcggaacg 3085141 ggcaggcgca aaccaaatca tcggaacttc agaatttatc agccgggcga tgctgcagca 3085201 ttaccaagtc aagttacggc cgtctaaaca gcagaacgga atcaagctga cacttgatca 3085261 gcatgtggag cttcttgctg ttcctgacga actaaaggga gcggcttaca aaacctgtgt 3085321 tctctatttc cttgatcaca acacaacaat tataggcata caaaaaaagg aggggccgat 3085381 gctttcccct cctcttacat acaaggtgct cgaaacagat caattccttg ccatctagtg 3085441 taacagaaca tcctccaatt ctttcacgag agaggcgccg atatccaaaa atgccggatc 3085501 aatttccgcg tcccgccttt ccggttcgga aaattgatta aacagtgatt ggaaaggccc 3085561 tccctcggcg tgatcgtcaa catccgcctg aaacacctgt ctcagcataa atggcgttcc 3085621 gatccggacg gccgcccctc gttcatcgag actgccctgt accgcattga cgggaattct 3085681 taaaaataaa tagccgtctc tatcatcaat tttataatca aagtagccat gatcgtattc 3085741 ccagccgccg tttatcacat aaccgagcgg cttcatcact tgttccagtt cttgaagcag 3085801 aaaagactgc ccatctatcg cggaaggtat tggtatcatc agaatgcccc ttttttcact 3085861 tatcctgtcc cgccgaacaa gacttcattc agaggcgcct acatggaaat cgttgtttct 3085921 ttcgcgcggc caacaggaaa gaaagcgcat tcaattaaga agtaaacagc cattgccgct 3085981 gcaagccata cagctgaatc ccaagacaca taaacaaccg ttgcatagag tcctaattta 3086041 gtgaaaagag tatgggttcg ttttaaatgc aaaatccgat gtaccgcatc ggtaaaaagg 3086101 gcaagcggca aaccaatgag aagaaaggag tggatgaaaa aatgtgacag cgtgccgcca 3086161 aagcttgaag aaaaccctgt atacacggca tcaaaggaga taaggaaact taaaatagct 3086221 gcagaaaaac cggcaatgat gagatgttta accaattgtt tcatgaacat cagcaccttt 3086281 ctgattttat aaaaagccga ccggcaaatg ccagtcagct ttctcacatt aatcttccag 3086341 acgtttttca agctctgctt ttttctcttc aaagccaggt ttgccgagta acgcaaacat 3086401 attgacttta tacgcttcta caccaggctg gtcaaacgga ttgacgccaa ggaggtaacc 3086461 gctcatcgcg caggcttttt cgaagaaata tacaaggtat ccaaaagtat atgcattcag 3086521 ctcaggaatg ttaacgatta agttcggaac atttccgtct gtatgggcaa gcattgtacc 3086581 ttggaatgct tttttgttaa cgaaatcaac agttttaccg gctaaatagt tcaagccgtc 3086641 aagatcgtta tccgcttcct caattgtcag ttcatgttta ggcttctcta cgttcaggac 3086701 cgtttcgaat aaatctctgc ggccttcttg tacatactgg cctaaagaat gaaggtctgt 3086761 tgaatagttc gctgaagaag gataaatgcc cttctcatct ttcccttcgc tttctccgaa 3086821 cagctgcttc caccattccg caaagtattg aagcgccggt tcgtagttga tgagcatttc 3086881 aattgttttg cccttattat aaaggacatt gcgaacaacc gcatattggt atgctgggtt 3086941 atcttccagt tcagatgttg caaaatcttt gctcgcatcc agggcgcctt tcatcatgtc 3087001 gtcaatgttg acgccgctga cagcaatcgg caagagacct acagctgtta aaactgaata 3087061 acggccgccg acatcgtcag gaattacgaa tgattcaaag ccttcttcgt tagaaagcgt 3087121 ttttaatgcg ccgcgctctt tatcagttgt tgcataaatc cgcgctttcg cttcttcttt 3087181 accgtatttc tcttcaagaa gcttgcggaa aatacggaaa gcgattgcag gttcagttgt 3087241 cgtacctgat ttagaaatca cattaataga gaagtcaaca tcttcaagaa gatccatgac 3087301 gtctctcata taagatgaac tgatgttgtt cccgataaaa atgacttgcg gattgccgcg 3087361 ttttgctttt ggcaaagtgt tataaaacgc gtgattcagc gcttcaatcg ctgcccgcgc 3087421 tccaagataa gaaccgccga tgccgacaac aagcaagaca tcagagtcag atttgatttt 3087481 ttccgcgctt tttttgatgc gcgcgaattc ttctttatca taatgttcag ggaggtccac 3087541 ccagcctaga aaatcgctgc ccgcgcctgt tttctcatgg atattatggt gtgctgtttt 3087601 tacaaagtcc cgcaggtatg taagttcatg ttcgttgaag aaagtcaacg cttttgagta 3087661 gtcaaagcgt acatgcgtca ttgcttgtcc ctccataacg gtataatgtt ttcatctttc 3087721 actttatatg aacttatctg tgaaatcaag tcaagaagaa agggcggaat gactggattc 3087781 cgccctttgg gtttatagag acgcgcgaag gatggcaagc acgtcatctt tgttcagttt 3087841 ttggaagttg ccgaagccgc cgtgttccat ttccttggct gcgatatcag caatcagctc 3087901 aagcttttct tctccaatat tgtaatcagc aagacgagaa ggtgcaccga ggcttgtcca 3087961 gaacgcagac agtttatcga ttccttcaag cgcaatttct ttatctgttt tgccttcagt 3088021 atcaatgtca aacatgttga gcataaggtt tttaaaacgg cctacatttg tatcaagcgt 3088081 gtatctcatc caatttggga acagtattgc caaaccgccc gcgtgcggaa tatcatatac 3088141 agctgaaaca gcgtgttcca ttgtatgaga agcccagtca ccgaagtatc ccatttggag 3088201 cgtgccgttt aaagcaatag taccagcata caaaatcgtt tcacgaagtt cgtagttttc 3088261 cagatcttca agaagcttag gagctgtttc gatgaccgtc tgcaaaacag caaagcacat 3088321 tctatcctga agcggcgtgt tttcaacatt atggaagtat tgttcgaata cgtggctcat 3088381 catgtcaacc atgccgtata ctgtttgatt ttctggaacg gtgaacgtat tttcagggtc 3088441 taaaatagag aaacgcggat gagtgacatt gctgccccat acaaatttct cgtttgtttc 3088501 ccagtttgta atcacggaat cagggttcat ttcagaccct gttgcagcaa gagttaaaac 3088561 agtgccaaac ggcagcgcat cctccgctgt tacttttttg ctgaaaatat cccaagcgtc 3088621 accgtcatat ttgacgccag ctgcgattgc ctttgtacag tcaatcacac tgcctccgcc 3088681 gacagcaagc agaaaatcaa tgtcatgctc tctgcaaagt cctatgcctt tttccactgt 3088741 cgcaagacgc gggtttggct ctacacctga cagctcatga acaacagcgc cctcttcttt 3088801 taaaatgcct gtgacttgat cataaaggcc gttgcgttta atgctgccgc ccccgtaaac 3088861 aagcagtaca ttcttgccgt atcgtttgaa ttcttttctt aattgttcaa gctgaccttt 3088921 tccaaaaatc agctttgtcg gattataata agtgaaattt tccatagtaa aacctccaaa 3088981 tgatgctggt aaaaaacaga ttttccattg taacataagt tgacaaaaaa gaaaaaggga 3089041 agcagccaaa cggctatttc cccttttttt atagtgatgc tttcaaaatt gacagcacat 3089101 cttctttgtt gagtgattta aattggccga atgtaccgtt agccattgcc ttgtcagcga 3089161 ttgtgtcaag ctgctcatca ttaatatcat aatcagcaag acggttcgga gcgccaagac 3089221 ttgtccagaa tgcggacagc ttatcgatac cttcaagggc aatttcttca tccgttttac 3089281 ctgcttcttc aacatcaaac acgcgaactg caagctgttt catgcgggca gggttttcag 3089341 acaatgtgtg tctcatccaa ttcgggaaca gaatcgccag tccgccggca tgcggaatat 3089401 cataaacggc tgatactgca tgttcaatat tatgagtagc ccaatcccct cttgccccca 3089461 tagaaagcat gccgtttaat gcgattgttc ctgtgtacag gatcgtctca cgcaattcgt 3089521 aattttcgag atcattgatc agcttaggcg ctgtttcaat gactgtacgc aaaagtgatt 3089581 cacacatgcg gtcctgatac ggcgtgtttg atacatgatg gaagtattgt tcgaatacgt 3089641 ggctcatcat gtcaaccatc ccgtagatcg tgtggttttt aggtacggtg aatgtattca 3089701 ccggatcaag aatcgagaat ttagggaata cgagcgggct gccccagccg tatttttctt 3089761 ttgtttccca gtttgtaata acagatcctg agttcatttc tgaaccagtt gcagcgagag 3089821 tcaataccgt tccgaatggc aaagcatctt ttggctgatg ctttttcgta acgatatccc 3089881 acgcatcacc atcatacttc gctcctgcgg caatcgcttt tgtacagtcg attacgcttc 3089941 cgcctccgac agccagcaag aaatcaatgt tttgttcttt acagatggca acacctttat 3090001 taacagtcga cacacgagga ttcggttcca cacctgctaa ttcatgcacg gtcgctccgg 3090061 ctttattcag ctgttcaatc acttgatcat acaggccgct gcgtttaatg ctgccgcctc 3090121 cgtacacaag caatacgttt tttccgtaag gtttgagttc ctccggaagt ctttccactt 3090181 cgccgcgccc gaaaattaat ttggtcggat tccagtatgt aaagttttgc atgacatctc 3090241 ctccttagat tttttattat gcagaatgtc ctcaccacat gtaaagcaat cagctctcac 3090301 cgatcagcat accagatggt tttattttgc aaggtgctgg gaaagaagct gatataagcg 3090361 agggcaggcc agcttccctc atatggagaa tgcatgtata gattctccaa tatgtcacaa 3090421 tctataactg ttttaataat tcatggagga ggttgcaaaa catgagtacc attcaaagaa 3090481 tttgtcttgt attaaccatc attggcgcca ttaactgggg actgatcgga tttttccaat 3090541 ttgacttagt agcggctatc ttcggcggcc aagggtcagc tctttcccga atcatttacg 3090601 gacttgtcgg aatcgccggc ttaatcaacc tcggtctgct atttaagcca aacgaggaaa 3090661 gatcacgtga agaagcagca aatcctgaaa tgcgatagga tatcaatcac gctgaaatag 3090721 gattttgcat gaaatcaaaa gcaccgaaca ttcctgtccg gtgctttttt catgcttatt 3090781 ttttgataag gtctttgcgg ttggacattt cgatccactc ttcaagctta tcttttaatg 3090841 tgttgaaacc ttgtggtgta gaagcttctt cgcttacttg agcagcttta ggttttcttg 3090901 gtttgctttc ttttttctca ggcgcagctt gtgtcgcacg aattgaaagg ctgattttgc 3090961 ctttttcttc atcaacagca agtactttta cttgtacttc gtcgccaact gaaaggtgct 3091021 cgttgatatc ttttacgaaa ccgtgagtca cttcagaaat gtgtactaaa ccttgagttt 3091081 cttcatctaa tgcaacaaac gcaccatacg cttgtaatcc tgtaacttta ccagtgtaaa 3091141 cactgcccac ttcaaatttt gctgccattc ataacaactc ctaagttaaa ttaaatatct 3091201 gtttatacgc aatttaaaat tatatcacac atgtcttatt tccgcaaaga aaactttttt 3091261 ataaaaaatc aggtttatgc acagcaaaaa gggggtaaac tgaaaatacc aaaggctttc 3091321 tagtattccc cccttttatt ggatgcgaac aaaaggttcg tatctttttt tatgttgttt 3091381 tgtgcaggaa gcgtttcatt ctgactaacg cttcttgaag ctgttcaatc gaggttgcgt 3091441 atgaacaacg gatatatccc tcaccgctcg gaccaaacac acttccagga acaactgcca 3091501 ctttttcctg cgtcagtagc tcctcggcaa actgttctga actcattccc atgcttttga 3091561 tagatggaaa agcatagaaa gcgccgcccg gatgatgaca gctgagaccg atttcattga 3091621 gcgattctac aaacagattc cgtcttcttc gatagctttt tttcattttt tctacgtctt 3091681 ccatgccgtt cttcaggcct tcaagggcgg caaactgcgc cattgcgggc gcgcacatca 3091741 tcgcatactg atgaatttta agcatggcat cccgaagcaa ggatggtgcc gcggcaaaac 3091801 cgagcctcca gcccgtcatt gcaaatgctt ttgaaaagcc tgagatgact accgtccgtt 3091861 ccttcattcc cggtaatgcc gctatacttg taaattcctc atcatatgtc agctccgcgt 3091921 agatctcgtc ggctaagacg atgacatcat gttttttggc aaactcagca atctcattca 3091981 gctcttcctt cgaataaacc gaacctgtcg gattcgatgg tgagcagatg agaatggcct 3092041 ttgttttttc agtgactgcc gcttcaaaat cagcagccgt tgctttaaat cctttgtctg 3092101 ccgttgtatg aacgtgaacc gggataccgc ctgccaaaga aacaagcgca tcgtacgcaa 3092161 caaaacacgg ctcaggaatg atgacttcct cacctggatt cacaatggcg cggatcgcaa 3092221 tatccaaagc ctgacttgcc cccactgtca caatcagctc attatctggc gagtagctaa 3092281 ggtcaaacct gttgctcaaa taacggctga tttcctcccg caatgagtat aaacccgcat 3092341 tggccgtgta tgacgtatat ccttgttcaa gagagagaat gcttgcttcg cggacattcc 3092401 atgcggtaac aaaatcaggc tcgccgacgc ctaaagaaat gacgccttcc atcgttgccg 3092461 ccaaatcaaa gaatttgcgg atgccggatg gttttatttg ttgtacatag tctgataaat 3092521 acgaagtcat ttacggtgac accacgattc ttttgtcgtc gtctcctgtt tcaaacactt 3092581 tgccgtcatg cttgtatttt ttcaggataa aatgggttgt cgtagataca actgaatcaa 3092641 gcgttgagag tttatccgaa acaaaacgcg ctacgtcaga catcgaattg ccgcgaatca 3092701 cgacagacaa atcgtatacg cctgacatca ggtaaactga ttcaacctct tggaatcggt 3092761 aaatccgttc cgccacttca tcaaaaccga cgccccgctt cggcgttact ttgacgtcaa 3092821 tcatggccgt aacgccctca tgtccgtcga cttttcgcca gtcaatcata gcggaataat 3092881 cgataataac cttttctttc tccagtttgt caataattgt tttcacttca tttacaggga 3092941 tgcccgccat ctttgcgatt gtttctaaat cggcgcggct gttttcgtct aaaatttcta 3093001 atatttctgt ttctttttct gtcaatttca tttgattcac acctttgcaa tgtcaagaaa 3093061 tctcatgaca ttatatcacg ttttttgacg aatgctaaga aaaaacgagg agaaacttcc 3093121 gctagaattg acaatttcag ggcataatac aaccatcaaa aaaagggagt gacacagaat 3093181 ggaggcggtt tcaccaataa ggcggtttac ggtcgatgga gtcaatgtat actacgaaca 3093241 ttatcaaaat cccggcaggc aaacgctggt ctgcgtacac ggttttttat catctgcatt 3093301 cagcttcaga aaagtaattc ctctccttcg ggacaagtac gacatcatcg cgcttgattt 3093361 gcctcctttc ggccaatctg aaaaatcaag aacgtttatc tatacctatc aaaaccttgc 3093421 taagcttgtc attgggattt tggagcactt gcaagtgaaa caggctgtgc ttgtcgggca 3093481 ttctatgggc gggcagatat cgctgtctgc tgctctccaa aaacctgagc ttttttcaaa 3093541 ggttgtgctg ctttgcagtt cagggtattt aaaacgttca cacccgacga ttattttcgg 3093601 gacccatatc ccgtattttc atctttacat caaacgctgg ctctcgaaag aaggcgtgat 3093661 gaaaaattta ttaaatgtgg tgcatgacaa atcgctgatt gatgaggaga tgattgacgg 3093721 ctatggcaga ccgtttcagg acgagcagat tttcaaagcc atgacaaggt ttatccgcca 3093781 cagagaagga gatttagaac ccgagcaatt gaagaaaatg aacaagcctg ctctattgat 3093841 ttggggcgag gaggatcgaa ttgtcccaat ggagatcggt aaacggctgc acgcagattt 3093901 gcctaattcc gtgctgtact cacttggcca gaccggacat ctggtgcctg aagaacggcc 3093961 tgaacttatt tctgaacaca ttgctgattt tatcaaataa caaaaaaacc ggtgctgaac 3094021 cggttttttt aaggcgtgca ggagctgctg tttttaatga ataaaagctg gccagccact 3094081 tcccggcagc tggcgatcgg cagcgtttgt tcaaaagaag tttcaaatat ttgctgaatg 3094141 cttttcgcca gcaagtcggg atcgttttca tcatagactg cctgcacgac atcaacagcc 3094201 tccgtttcgt aaaactcttc tccatattta aacgggtccc atttggcaat gatcttaatc 3094261 atttccctga ccgcatgact ttcttccata ttcatcaccg cttataataa aatttgcagt 3094321 tctatcttat catagtgaag cttagaagaa taaacataca tgagggggta acagaatgaa 3094381 ctttgataaa cgagaagaac gccttggcac ccaatcggtc aaatgggata aaacaggcga 3094441 attatttggc gtgacagacg ccctcccgat gtgggtggca gatatggatt ttcgcgcccc 3094501 ggaagcgata actgaagcgt taaaagagcg tcttgaccac ggtatttttg gttatacaac 3094561 tccagatcaa aaaacgaagg atgctgtgtg cggatggatg caaaacaggc acggctggaa 3094621 ggtaaatccg gaaagcatca cattcagccc cggcgttgta acagctttga gcatggcggt 3094681 acaagctttt acggagccgg gcgatcaagt agttgttcag cctccagttt atacgccttt 3094741 ttaccatatg gtggagaaaa acggccggca cattttacat aatccgctgc tagaaaaaga 3094801 cggcgcatat gcaatcgatt ttgaagattt ggagacaaag cttagtgacc caagcgttac 3094861 attgtttatt ttatgcaatc ctcataaccc ttctgggcgt tcatggagcc gggaagattt 3094921 actgaagcta ggcgaattgt gccttgagca tggcgtcaca gttgtatcgg atgaaatcca 3094981 ttccgattta atgctgtacg gacataaaca cacgccgttc gcttcgctct ctgacgattt 3095041 cgctgatatt tccgtgacat gtgctgctcc aagcaaaaca tttaatatcg ccggattgca 3095101 ggcttcagcg atcattattc cggatcgcct gaagcgcgcc aagttttccg caagccttca 3095161 gcgaaatggt ttaggcggac tgaacgcgtt tgccgtcact gcaatcgaag ccgcgtattc 3095221 aaaaggcgga ccgtggcttg atgaattgat cacttacatt gagaaaaaca tgaacgaagc 3095281 ggaagccttt ttgagcaccg agctgccaaa ggtcaaaatg atgaagccgg atgcatcata 3095341 cttgatttgg ctcgacttca gcgcttacgg cttgtccgat gcagagcttc agcaaagaat 3095401 gctaaaaaaa ggaaaagtta ttttagagcc cgggacgaaa tacgggcctg gcggagaagg 3095461 atttatgcgc ctgaacgccg gatgctctct tgcaaccctg caggacggcc tgcgccgcat 3095521 caaagccgca ttatcgtaaa tatagctgta aacgccttta cgtcttcatt tgtaaaggcg 3095581 ttcttaataa aggaatttta tattttactt ctaatattta gtgttataat agattcatat 3095641 tttatacgaa aggatttcac acgaatggaa attctaaaag actatcttct gcacatctgc 3095701 tttattttgt ttcctattct tctttaccaa gtgttttggc ttggaaaacc tgcgattctt 3095761 gtgccaaaaa taaacagcgg tttggtcacg ctcttcgcct gcggcgcctc cgttttatgc 3095821 attattttcc cgattcatga aatggactac atacaatacg gccttcagat gattcccgtt 3095881 atcatttgtt tattttacat tagtaccgct tccggactta cagtcgccgc atctgtccta 3095941 tgttttgaac tgctttttta cgaaccttcc gcaatgtttg ttttcacttt gctgcctttt 3096001 cttatcatta tcccaatctt atttcagaaa aaatggccat tcatgtccaa agcgaaaaaa 3096061 ctgctgctgt ctttattgat cagctgcgtg gagattttcc tatttttcgc ctcaagctgg 3096121 attctttccg ccttgaatat tttaaatttt caaaaatcag gaattttcgt ttacgaggcg 3096181 gcagtctcag ggcttttccg ctccagtgtt cttctattaa gcatctatat tatcgaaagc 3096241 atcgccgaaa atatcgccct gcgttcacag cttatccatt ctgaaaaaat gacgattgtg 3096301 agtgaactgg cagcgagcgt cgcccatgag gtcaggaatc cgctgacagt tgtccgcggg 3096361 tttgtccagc tgctttttaa tgacgaaacc ctacaaaaca agtcgagtgc ggattacaaa 3096421 aagcttgtac tgtcagagct tgaccgggcg caaggcatta tcacaaacta tctcgatatg 3096481 gccaaacagc aattatacga aaaagaggtt tttgacctat ctgcccttat caaagagaca 3096541 agctccctta tggtgtcgta cgccaattac aagtcagtaa ccgtcgaggc tgaaacagaa 3096601 ccggaccttt tgatatacgg agacgcaaca aagctgaagc aggctgtcat caacctgatg 3096661 aaaaacagta ttgaagcggt tcctcacggg aaggggatga tccacatatc agccaaaaga 3096721 aacggccata cgatcatgat taacatcaca gacaatgggg tcgggatgac agaccatcaa 3096781 atgcaaaaac tcggcgaacc ttattattcc ttaaaaacga acggaacggg actcggcctc 3096841 accgtaacct tttccattat tgaacatcat cacgggacca tttcatttaa cagcagcttc 3096901 caaaaaggca ctacggtgac cattaagctt cccgctgatc ttcctcacta gcaaatcgat 3096961 tggaacttta atagaataaa tgcgaggtga tgacagatga gcacgtttga gacaggctct 3097021 atcgttaaag gattttacaa aacaggtgta tacataggag aaatcacggc ttgcaggccg 3097081 cagcattatt tagtgaaagt gaaagcggtt cttacccatc ccgctcaggg agaccttcat 3097141 catccaaaac aggcggatgt gccatttttt catgagagaa aagcgctcgc atatggtgaa 3097201 cagaccaata tcccccacca tatggtgaag ccttatgacg gtgaagtgcc ggattatacc 3097261 gaatctctgc gggaggcgac agcacagatg agagccaaat tgaatgagga tggttcggag 3097321 tgggcaaagc gctcccttca taatctggac attttagaaa aagaatattt taaccggcca 3097381 taacccagtc tgacaaaaga ttgggttttt tacgtcgcgc gcttcaacag ttcggttaaa 3097441 tcgattctct cgccgattgt gggcggtttt ggcttttcga gatactgctt atcctgctca 3097501 acaagcttaa aaagtttata tgctgtgaga gcatcatcaa gcgctttatg atgggtgccg 3097561 gttccggaat ctccatactc ttcggcagct ttccataaac ccgtcaatgt ccggtctcca 3097621 aaaaagtttt tgtattcaag cgataaatct ctcatttctc ccttaaacgg gaaagggata 3097681 tggttaaaca tacagttttg cttcagcact ttcatatcca tgtttcccca cgtaataatt 3097741 gtgctgtttt tctcaggatc cagctcgttt agtttacgga tgaaatcctc gaatctcatt 3097801 ccttcgtcta cctgtttttg ggttattttt aaaaatgatt tgcagcgttt cgtaagcttc 3097861 gggaactttt tcggtctaac atagctagaa aacgtctcaa ccacttcatc atcaatcgac 3097921 tttacaattc cggcttcaat gatttccggg aagaagtttt gaggactgta ctttccatca 3097981 ggcattgtaa attcgaaatc aataatgagt aagctgtttg tcgtcacctt ttacacctgc 3098041 ctttcctccg atcagaaaat gctatcttta tagtatatca attccccttc tcgacatttc 3098101 ttcattttct aaaaataatg aattttccca gccgcttcgt ttcttttaaa ttgtgaatcg 3098161 tttctttata attagtaagg aacccgaaat aataagaagg tgatgttatt tctatccgta 3098221 agaaaaactt tgtcattgtg tggctggcga acttttttgt ctccgctagc acaacgatga 3098281 tcgttccttt tctctcctta tacattgaga cgctcagctc tttttcaaac ggctttgtgc 3098341 aaaggtggag cggctatgtg ttcggcatta catttctcat ggcgtttttg gtatccccgt 3098401 tttggggacg gttcggagac aaacgcggat acaagaaaat ccttatggca accggaacag 3098461 gcattgccct cagcattttc ttcatgggct ttgttacatc ggtgtaccaa ttgttttttc 3098521 tgcgtatggc aatgggtctt gtaaccggat tcatcccgac atctcttgcg atgatttcgg 3098581 cacagactcc gaagagctca gctggcaaaa cactcggcac gctgcaaatg gggcaagtgt 3098641 ccggaagctt gttcggcccg cttttgggag gcatgcttgc tgatcgtttc ggctttacgt 3098701 ataccttttt tatcacatcc tttgtgattt tctcgtctgt tcttctcgtg ttatttggtg 3098761 tcaaagaaaa gcatcttgca gagaaaacag ccaaacgtac gtcttactcg agaaaagaag 3098821 tgctctccta tatttttcac catccggcgc tgtgggtcat gatgctgtta accatgctga 3098881 ttcaaacagg caatttcagt atccagcccc tgctcgcttt atatgtaaat gagctgcacg 3098941 gacctgtcaa tcttgccttt ttctccggca tggcattttc agcaacgggg ctcggaagtt 3099001 tgctgctggc tagaaaatgg ggtgatctgg gcgaccgcta cggccaccgc cgcattttaa 3099061 tcggactttt gctcgccgcc tctttctttt ttattccgca ggcgctcgcg tcctcactca 3099121 gcgtgctcct tgttttcaga tttttattcg gaatggcgat gggcggtttg ctgccatgca 3099181 ttacggcagc gatccgcgtt caggctcccg gcagcattca aggtgaagtt ctcggctaca 3099241 atgtcagctt tcgcttttta ggaaacgtgc tcgggcctct gctcggcgga atcatatcga 3099301 gccattttac catttcggcc accttttacg tcacggcgtt tctctttttc gccggcgcct 3099361 gcatgctttg gatcatgcag aaacttcgga aagattctta tgccaaagca agctgattcc 3099421 gagaaaaaac taaggaatct tctaaattta accttctcgt aatctcaaaa gaatggtacg 3099481 atatggctag aatttaggag aaaagagagt gaccatgtta cgaaaaataa tcggatggat 3099541 tttgctcctt tgcataatcc cattgtttgc atttacagtt atcgcttccg gaaaagaagt 3099601 aaaacaaatg aagtccctgg atcaggtgct tgataaaaat attgatctga aagatatcag 3099661 ccttgttcag aacagctaca tgtatgacag ggacggctcc cttgtctcgg aaatcgtcag 3099721 cgaccacgaa aaccgtgtgc tcgttccatt taacaagatt cccgaggaag tcaaacagat 3099781 tttcttaaca tctgaggacc gccattttta cgagcataaa ggctttgact ttatgggaat 3099841 ggtgcgggct actgcttcta acgtaaaaga caagaaaatt gaccagggtg ccagcaccat 3099901 cacacagcag ctttcaagaa acttgtattt gagccacgaa cgctccttca gccgcaagct 3099961 gacagagctc gcgtattcct atcagctgga gaaaaaatat acgaaaaatg aaattcttga 3100021 agcttactta aataccattt atttcaacaa cggtgtttac ggcgtcggtt cagcagctca 3100081 attctatttc agcaaaccgc tgaaatctct cacagtggga gaaatggctt ttatctgtgc 3100141 tatacctaat aaccctacat tatatgatcc tctcaagcat tttgactaca cgaaaagccg 3100201 tcaagaacgt ttacttaaag ggctaaaaga tgccggggtc attacggaca aagagctgaa 3100261 aaaagccgta aaacaaaaaa tcaaactgga tgttgaaaaa agagaagaca aatatcctga 3100321 ctacgtttcc tacgtcaatg atgaattcac tcagctggtg tctgaatcag aaggctttga 3100381 taaacgcctt caaaaagcat caggaaaaca aaaagaaaag atcgagaacg agctgtccgc 3100441 aagagtcagc acgctgatga aagacggagt gaaaatttat actgcacttg atccgtacat 3100501 gcaaaatcaa gttgtggcac aaatgaattc caagctcccg tatgcggacg tacagggcgg 3100561 agcggctgtg attaatcacc agacgcatca aatcattgct ctatccggcg ggaaaaacta 3100621 tcaaaaatat gactttaacc gcgcctacca ggcgtacagg cagccgggtt catccattaa 3100681 gccgcttctt gattacggcc cttatattga acagaccggc gcgacaacaa gcagcaccat 3100741 tgatgccagc aagttttgca gcaaagacta ctgtccgcaa aactacaata accgcactta 3100801 cggcacagtg acgcttgata cggcgtttaa aaattcatat aataccccgg ctattagaat 3100861 gctcgaccgc gtcggcatcc aaaaggcatt cagttatatt gagccgtatc attttgccaa 3100921 acttgtcgac agtgactatc ttcttccggc ggcgcttggc ggatttacaa acggcatgac 3100981 gcctcttgag atgacaaagg cttatacgac attcggaaac agcggaagct atacgccgag 3101041 ccatgcgatt acaaaggtga cagaccttaa aggaaaaaca ctttataaat ggaatgataa 3101101 agcgactcaa atattcagcg tccgcacgaa catgcagctg aaaaaactga tgtcttccgt 3101161 tgtgaaaagc ggaacaggga aaaaagcata tttcaatgcg ccttacatcg gcggtaaaac 3101221 cggaacatca aatgattatc acgatatgtg gtttgtcggc ctgactgata cgtatacaat 3101281 gggtgtctgg gtcggaaagg atacaccgac cagcgttgaa tatcttcaca gcatcagccc 3101341 tcagctttcc atctggaaag gaacgctgca agcggcttat taaaggatcg gaggggatat 3101401 ggagtgactt cagaacaaat tccaaatcgc gttttgctgt ttgacggtgt ctgcaattta 3101461 tgcaatggcg ccgtgcagtt tatcattaaa cgtgatccgg acggattgat ttctttcaca 3101521 tcgctgcagt cggaaacagg acagagcctg ctgaaaaaaa gcgggcttcc gactgatcgg 3101581 tttgacagct ttgtctttat tgaagacggc caagtgtaca caaagtcaac tgcagccatt 3101641 aaggttttca ggcatctgcg aggcccatgg cggctcttcg tccttttttt cgcagtgccg 3101701 aagcctgtca gagatatggt ctattctttc attgccaaaa accgctataa gtggtttggc 3101761 aaaaaaaatg aatgtatgct cccctcccct tccattaaaa aaagattttt accgtaaata 3101821 aaaaatggct aggaagctag ccatcacaga ttgttgacaa aatcctaaaa cggcttcgtt 3101881 ttaggatttt gtcatctatt cagcgtgatt gaaaactttt gaagttgtga aacggcggaa 3101941 acctgagaat ctagccgccg tttcattgcg tacagagcac gaagcgcaaa tctgaccacc 3102001 aaacgctgaa atggctagct tacacaggta agctagccat tatgctatta taaagcttga 3102061 taaatatgaa cagaataccg ataacaaagg taaaccaaaa cagcagttcc aatagaatga 3102121 atccaactaa tgacatgaga gaaagcgtcg aataaatccg gtatacggta aacacaaagt 3102181 aagcgagcgt gacgaccgca aaccagatca caatccaaat gacattttgc aagagcacaa 3102241 aggataaaat cccgccgccc aaataaatca tggaacccat tctgagtttt ttcaggttgt 3102301 tcccttccgg atcattagca aaaaacagca atgacagctc ggtcacggta tttgcaatta 3102361 atttcagagc ggacagaacc ataaaatata aaagtgcaaa ggcagcaaat aacgcaagcc 3102421 tgattccttt ctctgaaaaa taatcgagca ttccatcata cattccaaat gaagacagca 3102481 tcttcaacgc ataaagtgaa gttgagatgg ataaggacga actaaaaagc aggatcgcaa 3102541 tcagcggaaa atatcctgtc aaataagtat ttttcatata aaaaagtccc tttctataat 3102601 ctacctcatt tattatggag gacttaaaac acattgacaa gataaattat tccatttttt 3102661 ctccttttta cgaattacgg gcccaaatct tcacaaagca gcattttgag agtaaagtag 3102721 tacgcaggaa tcataaaacg taaggaagtt ttatatgaaa aaaacattaa aactgcaaac 3102781 cagactcacc atatttgttt gtatcgttgt attaatcgca ttgctcatta cgttttttac 3102841 agtcggtgcc caaaccacca aacgaattag agatcaggaa aaggccactg cgctgcagac 3102901 tgctgaaatg gtagctgaag cgccgatgac agccgctgct ttagaaagcg gaaaaaaaca 3102961 aaaggaactg cagagctaca caaagcgggt tcagaaaatt accggcacgg aatttgttgt 3103021 cgtcatggat atgaacggta tccgcaaaac tcatcctgac ccgagcaaaa tcggaaaaaa 3103081 attcagaggc ggtgatgagt ccgaggtatt aaaagggcat gtccatatca gcacagcctc 3103141 tggcacgctc gggaaatcgc agagagcgtt cgtccctgtc tacgcggaga atggaaaaca 3103201 ggtcggtgca gtcgcggtcg gcatcaccgt aaatgaaatt gatgaagtga tcagccatag 3103261 cttacggccg ctttacttta ttatttgcgt cagcatcttc gtcggtgtga tcggagccgt 3103321 tatcgtcgcc cgtacagtga aaaatatcat gtacggactt gaaccttatg aaattgcgac 3103381 tctgcttgaa gaacggagcg cgatgctgga atcgacgaag gaaggaatac tcgctgtcga 3103441 tgaacatggc aaaattaaac ttgccaacgc ggaagcaaaa cgcctattcg tcaaaatggg 3103501 catcaacaca aatcccattg atcaggatgt agatgacatc ttgccgaaaa gccgcttgaa 3103561 aaaggtcatt gagacaaaaa aacctcttca agacagagac gtccgcatta acgggctgga 3103621 gcttgtgttt aatgaagttc ctatccagct gaaaggacaa actgtcggag cgattgcaac 3103681 attccgcgac aagaccgagg taaaacattt agctgaacag ctttccggtg ttaaaatgta 3103741 tgcaaacgca ctgagagcgc agtctcatga atttatgaac aaactgcatg tgatattagg 3103801 tctcgtccag ctgaaagagt atgatgatct tggagattat attaaagata tagccataca 3103861 gcaaaaatca gaaacaagtg aaattataaa tgatgtcaaa agctccgtac tggccggttt 3103921 tctgcttgga aagcaaagct ttatacgtga gcagggcgca aatcttgata ttgaatgcaa 3103981 cggtgtcatc ccgaacgcgg cagacccttc tgtcatccat gaacttatta caatcatcgg 3104041 aaatctcatc aacaatggct tagatgccgt tgccgatatg ccgaaaaaac aaatcaccat 3104101 gtccatgcgc ttccataaca gcatacttga tattgaaatt accgatactg gagcaggcat 3104161 gtctgaagaa gaccaagcca aagtatttga acaaggctat tcaacaaagg gcaaaaaccg 3104221 gggattcggc ctttatttca cacagcaaag catcgaaaat ttaaaaggcc aaatgatcct 3104281 cacaagcgaa aagaatgaag gaacgacatt cagtattcgc atcccgtacg aaccgaagga 3104341 ggaaaatcat gattaatgta ctaatagttg aagatgaccc catggtgggt gaattaaata 3104401 aacgatactt aagccaaata gatggctttc agctgaaagg catcgcttct tcctttcaaa 3104461 gcgctctgca tattttaggg gagcaccata ttgacctcat tttgcttgat atttatatgc 3104521 cgggaaaaaa cgggctggaa ctgctgacgg aattgagagc ccaaaatgaa gcggttgacg 3104581 tgattgtcat ctcagcggcc agcgagcttg acgtgatcaa gaaaacactt cggtacggag 3104641 ctgttgatta tttaatcaaa ccgtttgaat ttgaacgatt ccaaacggct ctgtctgatt 3104701 acagacgaaa acaaaaggtg tattcaaccc atcgcaacat gagccaaaaa gaactggacg 3104761 ccgagctttt tcaaaagaaa gaagcaacag aaaaagtgca gcttcctaaa ggcctgacaa 3104821 aaagcacgct gaagctgatc tggtccagta tccagtcatt tgaaaatgaa tcttttacga 3104881 cagaagactt ggcaaagcac acagaaatct ctcaagtatc catacgaaaa tacttaaagt 3104941 ttcttgaaga tatacaggtt ctgaatgtag aaatggcgta cggaacgatc ggaagacctg 3105001 tgtttcagta caacgtcaac aacagtaaca ttaacggaat aaagcaatat ctataagaaa 3105061 acgcactgct tgctttgagc agtgcgtttt tctgtcatat ctcttgccaa gatgcttgat 3105121 tctattgttg ataagttata caagaataac aaagggcttt cacattttta agcaaataat 3105181 tctaaaaata gataattttt aaaaaattat gcgaaattct atttatttct tattagttaa 3105241 atgataaatt atgattggtt agttgatccc gaaaaactaa gtcataagtc ttacttcaga 3105301 aaacgatgtc acggttttcc gcccggaacg ccttccgcat ccttctcttc cccgcctttc 3105361 gaaggaaata ctcacaccac gcttattcag ggaagaatag aactgtctca gcgcattcca 3105421 tttgttatta tcagaaaatt ttatcgattc taagaaattg ttcaggacag cccatcacat 3105481 gactggccgg atcagctttg aaccaaattt ttctgggggg ttatatcttg aataaacgaa 3105541 aaatcggatt ggcgatgtca cttgtgatcg cagcaggcac catattagga gcatgcggaa 3105601 acagcgaaaa aagcagcggc tcaggcgaag gcaaaaacaa attcagtgtg gcgatggtta 3105661 ctgacgtagg cggagtggat gacaaatcct tcaaccaatc agcctgggaa ggcatccaag 3105721 cctttgggaa agagaatggg ctgaaaaaag gcaaaaacgg ttacgactat cttcaatcca 3105781 aatctgatgc agactataca acgaacttaa ataaattggc gcgtgagaat tttgacttaa 3105841 tttacggcgt cggctactta atggaggatt caatcagcga aattgctgac cagcgtaaaa 3105901 atacaaactt tgcgattata gatgctgttg tcgataaaga caacgtcgca agtattacgt 3105961 ttaaagagca ggaaggctca tttctcgtcg gagtggccgc agccctatca agcaaatcag 3106021 gaaaaatcgg ctttgtaggc ggcatggaat cagagttgat caaaaaattc gaggtcggct 3106081 tccgtgccgg cgtgcaagca gttaacccta aagccgttgt agaagtgaaa tacgcagggg 3106141 gtttcgataa agccgatgtc ggtaaagcaa ccgccgaaag catgtataaa tcaggcgtag 3106201 atgttattta tcactctgcg ggcgccactg gcacaggcgt ctttactgaa gcgaaaaacc 3106261 tgaaaaaaga agatccaaaa cgcgatgtct gggtcatcgg tgtcgataaa gaccaatacg 3106321 cagaaggcca ggtagaagga acagatgata acgtcaccct cacttccatg gtgaaaaaag 3106381 tagatacagt cgttgaagat gtaacgaaaa aagcgagtga cggaaagttc ccgggcggcg 3106441 aaacacttac ctacgggctt gatcaagacg gagtcggcat ttctccatct aaacaaaatc 3106501 tatcggatga tgtgatcaaa gcggtcgata aatggaagaa aaaaatcatc gacggattgg 3106561 aaatcccggc aactgagaaa gagctgaaaa ccttcaaagc tgaataagaa tcgcagggat 3106621 aaggaggtcg agcccttatc ccttgttttt cttttatttt gaaataaagg agcggtcaat 3106681 caatggaata tgtcattgaa atgctcaata tccgcaaggc gtttccaggt atcgtcgcca 3106741 atgacaatat caatcttcaa gtcaaaaaag gcgaaataca cgcgttgctc ggtgaaaacg 3106801 gagcggggaa atcaacattg atgaatgtcc ttttcgggct gtatcagccg gagcggggtg 3106861 aaattcgggt gcgcggcgag aaggtgcaca tcaacagccc gaacaaagcg aatgaccttg 3106921 gaattggaat ggtgcaccag cactttatgc ttgttgacac ctttacagtt gctgaaaata 3106981 ttattctcgg gaaggagcca aagaagtttg gcagaattga ccggaagcgt gctggccaag 3107041 aggtgcagga catttccgat cgatacggcc tgcagatcca tcctgaagca aaagcagctg 3107101 acatatcagt cggtatgcag cagcgcgcag aaatattaaa aaccctctac cgcggtgccg 3107161 acattctgat ttttgatgaa ccgacggctg ttttgacgcc tcatgaaatt aaggaactga 3107221 tgcaaattat gaagaacctg gtcaaagaag ggaagtccat catcttaatc acccataagc 3107281 tgaaagagat tatggagatt tgtgaccgcg ttacggttat ccgtaaagga aaaggcatca 3107341 aaacccttga tgtccgtgat acaaaccaag acgaactcgc cagtctaatg gtcggccgtg 3107401 aggtatcgtt caaaactgaa aagagagctg ctcagccggg agcggaagtg cttgcgattg 3107461 acggcataac tgtaaaggat acccgcggaa tagagacagt cagagatttg tctctttctg 3107521 tcaaagcggg agaaatagtc ggcatagcag gcgtcgacgg aaacgggcaa tctgagctga 3107581 tcgaagcggt gacaggactc cgcaaaacag attcaggaac aatcacctta aacggaaaac 3107641 agatccaaaa cctgacgcca agaaaaatca ctgaatccgg gatcgggcat attcctcagg 3107701 atcgccataa acacggtctc gtccttgatt ttccaatcgg agagaatatc ctgctgcaaa 3107761 gctattacaa aaagccgtat tcagcattgg gcgttttaca taaaggcgaa atgtacaaaa 3107821 aagcacgcag cctgatcact gagtacgatg tcagaacgcc ggatgaatat acacacgctc 3107881 gggcattgtc aggcggaaac cagcaaaaag cgattatcgg gcgggaaata gaccgaaatc 3107941 ctgatttatt aattgccgcc cagccgactc gcggccttga tgtcggagcg attgaatttg 3108001 tccataaaaa gctcattgag cagcgtgatg ccgggaaagc cgttcttctc ctctcgtttg 3108061 agcttgaaga aattatgaat ctcagtgaca gaatcgccgt tatttttgaa ggacgcatta 3108121 tcgccagcgt taatccgcag gaaaccactg aacaggagct tggtctcttg atggcaggaa 3108181 gcacgcaaaa ggaagcgggg aaagcaaatg gttaaacgac tctctcattt actcgtgccg 3108241 ctcatcgcaa tcatacttgg tcttgcggcc ggcgcgttga ttatgcttgt gagcggctac 3108301 agtgtggcta gcggatattc ggctttgtgg aatgggatat tcggagaaat ctattatgtc 3108361 ggagaaacaa tccggcaaat tacgccttat attttatccg gattggctgt cgcctttgca 3108421 ttccgaaccg gactctttaa tatcggcgtc gagggacagc tgctcgtcgg ctggacagca 3108481 gcggtttggg tcggtacggc gtttgacgga ccggcatata ttcacttgcc gctcgcattg 3108541 attacagcgg cagctgcagg aggattatgg gggtttattc ccggcatttt gaaagcgcga 3108601 ttttacgttc atgaagtcat tgtcaccatt atgatgaatt atatcgcgct gcacatgacc 3108661 aattacatca tttcaaacgt cttgacagat catcaggaca agacggggaa aattcacgaa 3108721 tccgcctccc tccgctctcc ttttcttgaa cagatcaccg attactcacg gctgcatttg 3108781 ggaatcatcg ttgcccttct cgcagcagtt atcatgtggt ttatcatcaa caaatctaca 3108841 aaaggatttg agctccgggc ggtcgggttt aaccagcacg cttcccagta tgccggcatg 3108901 agcgtgcgga agaatatcat gacctccatg cttatctccg gcgcttttgc aggtcttgcc 3108961 ggagccatgg agggcctagg gacattcgaa tacgcagcag tgaaaggcgc atttaccggc 3109021 gtaggctttg acggtatcgc tgtcgctctt ctcgggggaa acacagccgt aggcgttgta 3109081 ctggcagcat gcctgcttgg cgggctgaaa atcggcgcat taaatatgcc gattgaatca 3109141 ggcgttccat cagaggtcgt tgatattgtg attgccatta ttattctatt tgtggcttca 3109201 agctatgcga ttcgtttcgt catgggcaaa ttgaagaaaa agggggcgaa ctaagtggac 3109261 attgtgcaga ttttatctat cattgtccct gccacactcg tctatgcggc cccgcttatt 3109321 ttaactgctc tcggcggcgt gttttccgag agatcaggtg tggtgaatat cggcctagaa 3109381 ggcctcatga ttatcggggc gttcaccagc gtgttattta atttattttt tggtcaggaa 3109441 ttaggtgccg ccgcaccttg gctttcgctc cttgccgcca tggcagcagg cgccctgttt 3109501 tcactgattc acgcggcagc ggcgatttcg tttcgcgccg accagacagt cagcggtgtc 3109561 gccattaaca tgctggcgct tggggcaact ttatttatcg tcaaactgat ctacggcaaa 3109621 gcgcagacag acaaaattcc agagcctttt tataagacga aaatccccgg tttgggcgat 3109681 attcccgtct tgggaaagat cttcttttcg gatgtctatt atacgtctat tcttgcaata 3109741 gcacttgcct ttatttcctg gtttatcttg ttcaaaacgc cgttcggcct tcgtatccgt 3109801 tctgtcggcg agcatccgat ggcggccgat acgatgggaa tcaacgtata taaaatgcgc 3109861 tacatcggcg tgatgatcag cggattgttc ggcggtctcg gcggcggcgt atatgcctcc 3109921 acaattgcgc ttgatttcac gcactctacc atctccgggc aaggttttat cgccctggca 3109981 gcgcttgtat tcggaaaatg gcatccgatc ggagcactgg gggccgccct gtttttcgga 3110041 ttcgcccaaa gcttaagcat cattggatcg ctgctccctc tttttaaaga cataccaaat 3110101 gtgtatatgc tgatggctcc ttatatctta acgattctcg ctttaaccgg ctttatcggg 3110161 cgggcagatg cgccaaaagc caatggcgtg ccttatatta aaggaaaaag ataaacattc 3110221 tcccctggga agacgattct cagggatttt tttctaatcc aaaagacccc cttaatttaa 3110281 ttgtttatta gttttttaac ttaaaaaaat atgaagtgtt aacgctttct tgtagactgt 3110341 aacaaacaat acatgggggt gtatgacatg ggagcaattc caaaaacggg gacaatttca 3110401 cctgagcaaa aagactcaca ggagaaaaac ctgtttcaaa aaatttggtc ttgggaaatc 3110461 ggtgtgattc ctttgccatt atacacagta ttagctgtta ttattattct tgcagcatat 3110521 tacaatgagc tgccggcaaa tatgcttggc gggtttgcca tcattatgat tcttggtgtg 3110581 tttctcggag acataggcca acgcataccg atattgaagg atattggcgg ccctgctatt 3110641 ttatctttgt ttgttccttc atttttagtc ttttacaatg tactgaattc aacatcttta 3110701 gacgctgtaa ccaacttgat gaaaacgtct aacttccttt atttctatat cgcttgcctt 3110761 gttgtgggaa gtatcctcgg tatgaacaga attgttttaa tacaggggtt tatcagaatg 3110821 ttcgttccac tggttgcagg aacgatcgcg gccgttgcag ccggcatcct tgtcggattt 3110881 atttttggct atagtgccta tgattccttt ttctttgttg ttgtcccgat tattgccggg 3110941 ggaataggtg aagggatttt gccgctttca atcgcctatt cacaaatact gggctcatcc 3111001 gccgatgtat ttgtgtctca gctggtgcca gccgcaatta taggaaacgt ttttgctatc 3111061 atatgtgcag ccttaatgaa aaagcttggc gacaagcgtc cagatctaaa tgggaacgga 3111121 cgtctcgtaa aatctaaaaa agcaaatgag attttcaatc aaaaagaagc cgaagcaaaa 3111181 attgatttta aactaatggg agcaggagtt ctgctcgcgt gtacattctt tatttttggc 3111241 gggttattgg agaaattcat cttcatcccg ggcgcgatct taatgattat ttcagctgcg 3111301 gctgtcaagt atgcaaatat tcttccgaaa aaaatggaag aaggcgctta ccagctttat 3111361 aagtttattt cttcaagctt tacatggccg ctgatggtcg gtctcggcat cctctttatt 3111421 ccgttggatg acgtagcgtc tgtgatttct ataccgtttg tcatcatctg tatttcagtt 3111481 gttatcgcga tgattggttc tggatatttc gtaggcaagc tgatgaacat gtatccggtt 3111541 gaatccgcaa tcgttacctg ctgccacagc ggtctcggcg gaacgggtga tgttgccatt 3111601 ttatcggcat caggaagaat gggccttatg ccgtttgccc aaatttcaac ccgtctcggc 3111661 ggtgcaggca cagttatttg cgcgacagtg ctgcttcgtt ttttcacttc ataaacagaa 3111721 agagttccgt tttatgcgga actctttttt tatttattca caatccgaat atactctcgg 3111781 ggaccaaacg gcagatcctt tgattccgtc tcactcattc tggctgacag gtggtgctcc 3111841 agtaaataca gctcccactc atcacaagcc gccacaccgc tgcgcccgtc atattgattc 3111901 aacatgaatg cccctgcaaa tactgagcag aataaacctg agcacatcac gacttttgtt 3111961 ttcacatgac cagctccttt ccttcagctt gatcaggatt gattttaaat atacaaataa 3112021 cctctttttt gttagactta ttttgaggtc aaaagaactc ataaaaatcc attacagcag 3112081 ttcgaagcgt ggcagcttgc agaaaagtgc gatataattt ggactaggtc gtttgaccgt 3112141 atattttata catagcgcat ttttcaattg agaacgagaa aaggaggtct tatctttgca 3112201 gctcttacat cttgctattt tatcgccttt tttatttgct tttatcattc ccttcttggc 3112261 aaaatacgca aaaagagtgc atacgggctg gtttgtgttg atcctgcccg tcttgctgtt 3112321 tatatacttt ctcccaatga tcaggatgac gcaatctgga gaaacacttc gatcggtatt 3112381 agagtggatt ccgtcactcg gcattaactt taccgtttat atagacggcc tcgggttatt 3112441 attcgcttta ctgatcacag gcattggctc tttggtcact ctttacagca ttttttattt 3112501 atcgaaagaa aaagaacagc ttgggccctt ttatgtctac ttattgatgt tcatgggcgc 3112561 catgctcggc gtcgttctag tagacaatgt catggttctc tacatgttct gggagcttac 3112621 aagcctttca tcctttttgc tgatcggcta ttggtataag cgggaaaagt cgcgctatgg 3112681 cgcagccaaa tcacttttga ttacggtcag cggcgggctg tgcatgctcg gcggatttat 3112741 tctcctttat ttgataacgg attccttcag tattcgagag atggttcacc aggttcaatt 3112801 aattgccggc cacgaattgt ttatcccggc tatgattctc attttattag gggcttttac 3112861 gaaatcggcg caatttcctt tttacatctg gctccctgac gcgatggaag ctccgacgcc 3112921 tgtcagcgct tatctccatt cagctactat ggtaaaagcc ggcatttatg tgattgcgag 3112981 attcagtcct attttcgcct tttcagctca gtggttttgg atcgtgtccc tcgtcggcct 3113041 ctttacgatg gtttggggtt cattccatgc cgtgaaacaa actgatttaa aatcgatttt 3113101 ggcgttttca accgtcagcc agctcggcat gatcatctcc atgctcggag tcagtgctgc 3113161 ggcccttcat tacggacata cagaatatta tacagttgcc gctatggctg ccattttcca 3113221 tttgatcaac cacgcaacct ttaaaggaag cttgtttatg gcagtcggga ttatcgatca 3113281 cgaaacaggc acacgggata tccggaagct aggcggcctg atggcgatta tgccgattac 3113341 ttttaccatt tccttaatcg ggacattttc aatggccggc ctaccgccgt ttaacggatt 3113401 tttgagtaaa gaaatgtttt tcacaagcat gcttcgcgtg acacattttg acctgttcaa 3113461 cgtgcagaca tggggcgttc tgttccctct tttcgcctgg atcggaagtg tatttacgtt 3113521 tatctacagc atgaaattgc tgtttaaaac attcagagga aattaccagc ctgaacagct 3113581 tgaaaaacag gctcacgaag cgcctgtcgg tatgctcgtt ccaccggtca ttcttgtcgc 3113641 tttggctgtc agtctcttct ttttcccgaa tatattgtcg tacagcctga tagagcctgc 3113701 gatgaactca atctatccga cactgcttga cggccatgag aaattccacg ttcacatttc 3113761 acagtggcat ggggttacaa cggaattgct catgactgcg ggtattgttg tgatcggaac 3113821 aattggttat ttgtcgctga ataagtggaa aggaatctat aaactgtttc cttcgaaact 3113881 cacactcaac cggttatacg ataagctttt gactatgatg gagaaaggct cttaccgggt 3113941 cacaaaacaa tatatgaccg ggtttttaag agattatttg ctgtatatct tcgctggttt 3114001 catcattctg ataggcggag cttttgccat taaaggcgga ttttcattta aaacggaagg 3114061 catggctaaa atcggtgtat acgaaatcat tttgacgctt gtcatgatca gcgccacagt 3114121 ggcgactgtt tttgctaggt caagactgac ggcgatcatt gcactcggtg ttgtcggtta 3114181 tacgcttgca ttgttttttg tcattttcag agcgccggac ttggcattga ctcagctcgt 3114241 cattgaaacg atttctgtgg cactgtttct gctttgcttc taccatttgc cgaaactgag 3114301 gctgaaaaca aaaacgagaa cgttccggat gacgaatttt atcatttctt taggcgtcgg 3114361 tgttatcgtt acactgctcg gcatcgcatc ctcaagccag cggacaaaag acagcattgc 3114421 gtccttcttt gtcaaacaca gccacgatct cggcggaggg gataatgtcg tcaatgtcat 3114481 tctcgttgat ttcaggggat ttgatacaat gtttgaaatt acggtattaa cgatagccgc 3114541 tctcggcatt tacagcatga ttaaaacaaa agtaaaagag gaggggaaaa gcggtgaatg 3114601 aacaaaaaac aaatgacttg attcttcaaa ccgcgacaaa gcttgtatcc tttatcattt 3114661 tgcttttctc tttctattta tttttatcag ggcataacgc gcccggagga ggctttgtcg 3114721 gcggactgat cacgtcctct tccatcgttc tcttgctctt ggcatatgat ttaaaaaccg 3114781 tgcgttccct tttgcctgtc aatttcattt atgtcgcggg agccggcctt ctgctcgctg 3114841 tattaacagg cgttggctcc tttgtcttcg gggctccttt tttaacccac acattcggat 3114901 actttcagct gccgatcctt gggaaaacgg agctcgccac agcgacgata tttgatttag 3114961 gcgtttatct tgttgtcgta ggcataacga tgaccattat tcaaacgatt ggagaggaag 3115021 aataatggaa atcttaatgg ctgtattagc cggtattatt tttatggctg ctacgtattt 3115081 gctgctgtct aaaagcctgc ttcgcgtcat tatcggaaca gcactgttaa gccatggcgt 3115141 tcatttaatg cttttgacta tgggaggatt aaagaaaggc gccgctccga ttttgagcga 3115201 gcatgccaaa tcatttgtcg atccgcttcc gcaagccctg attttgaccg caattgtcat 3115261 ttcttttggc gttacgtcat tcatcctcgt catggccttt cgcgcttatc aggaattgaa 3115321 atcggacgat atggatcaaa tgaggggaaa tgatcaacat gaataatttt gttattttgc 3115381 caatcctgat cccgcttttg tcggctattc ttctgatttt catgacgaag aatcttatgc 3115441 tcatgagaat cttcagcacg gcggcatcgg ccatcgggat tgtgattagc ggcatacttg 3115501 tacagactgt cttcacaaaa ggcatccaga cactcagcct aggcggatgg aaagcgccgt 3115561 acggcattgt gcttgccgca gaccaattcg ccagccttct cgttctcaca acagcgatca 3115621 tcggtttatt ggttgggctt tattccttcc gttctgtcgg tgaaaaacgg gagcgctcct 3115681 tttactactc cggcgttcag ttcttgcttg ccggcgtcag cggagcgttt ttaacaggcg 3115741 atttatttaa tatgtacgta ttttttgagc ttctgcttat tgcttcctat atgctgattg 3115801 tattaggcgg cacaaaaatt cagctgcggg aatcccttaa atatattgtg tttaatattg 3115861 tatcgtctgc cctgtttgtc ataggggtcg gctttttata cgctgtaacc ggtacgttaa 3115921 acatggcgga tcttagcgtg aaaatcagcg aatcaggaca aaccgggctg atcactgtga 3115981 ttggtgtcct gctgcttttg gtatttggca tgaagggcgg aatcttcccc ctctactttt 3116041 ggcttccagg ctcttattac gcgccaccgg cggcaatctc cgcgttgttc ggcgctttgc 3116101 tgacaaaagt cgggttatat gcgattacga gggttttcac attgattttt attcacgata 3116161 cagcctttac ccatcagttg atgatttggc tggcggcgct gactgtgatt tttggtgtga 3116221 tcggttcact cgcttattcg aatgtcatga aaattgtgat ctataacatt attaccgctg 3116281 tcggcgtgat tttgttcggt gtggcagtac acacccccgc atccattcag ggcgcgatct 3116341 actatctgat tcacgatatg ctgattaagg gcgctttgtt catgctggca ggtacgctga 3116401 tcgcattgac tggaaccgcg agcctgcata aaatgggcgg gctgatcaaa cgctatcctg 3116461 ttcttggatg gatgtttttc atttccgcta tttctcttgc aggcattccg ccactgagcg 3116521 gatttgtcgg caaatttaaa attgcagagg gcggcttcgc agaaggtgaa tttacgatat 3116581 ccatgctgat tctgctttcg agtctgcttg tactgtactc tgtgctgagg atctttatac 3116641 atgcgttttg gggcgaagaa aaagaaacgc caaaaccaaa tcatcgaaca gctaaaggac 3116701 ttctttatcc ggcagctatt tttctcttgc tgtcccttct cttcggattg ggtacagaat 3116761 gggtgtcgcc ttacgttgat caagcggccg agacgctgct gaatccggaa aaatatatcg 3116821 aagctgttct gaaggagtag atcgcatggc atttcaaatt ttattaaatg tgtttctcgc 3116881 tttttgctgg atgttcttaa gcaacagtcc aagcgccgca ggattcatta caggctatat 3116941 tctgggaatg ctctctctct ttttcttccg gcgctttttc actcgccagt tttatctatg 3117001 gaaattgatt tctattatca agctctgttt catttttata aaggaactgt accttgccaa 3117061 tgtcagtgtg atgaaatcag tcttatctcc aaaactgaat atcagaccgg gtatttttgc 3117121 ttttaaaact gaactgacga aggactggga aatcaccatg ctttctctgc tcattacatt 3117181 aacgccggga accttggtga tggatatttc agatgacaga acaatacttt atattcatgc 3117241 aatggatatc gaggatgcgg aaaaagcgat ttttgacatt cgggagtcat ttgaaaaagc 3117301 catacaggag gtgagccggt gatgtttacg ctgatcctgc aaatcgcgct cggcattatg 3117361 gcagtgtcta cctttttgta tgtcattcgt gtcattaaag gtccgactgt gcctgaccgg 3117421 gtcgtggctc tggatgcaat cggcatcaat ctgatcgcaa tcacggcgct tgtctccatt 3117481 ttgctgaaaa caagtgcgtt tttggatatt attttgttgc tggggatttt atcgtttatc 3117541 ggaacgatcg cattttccaa gttcctggag aaaggagaga ttatcgaaaa tgatcgaaac 3117601 cgctaaggtc gttgtggctg tattcatttt gctgggtgct cttatatgcc tcattgcttc 3117661 atttggcgta cttcgccttc ccgatgtgtt tacacgcgct catgctgctt ctaaaggctc 3117721 aacattaggt gtcaatatga ttctgctcgg tgtcttcttc tatttgtggt ttgtgacggg 3117781 ggagctctcc gctaaaatcc tgcttgggat tctctttatc tttattacgt cgcctatcgg 3117841 cgggcacttg atctgccgtg ctgcgtataa ctccggcgtc aagcttgatg agagaagtgt 3117901 gcaagatgac tataacggaa tcagaaactt tgtgattaaa cgaaaagagg attcttattt 3117961 ataaaaataa gcagccggac aggcagagtt ccggctgttt ttttatttct tgatgacagc 3118021 cagcgtgcat ctggatatac agatcagcct ctcttgctcg tcatatatgt gaatatgata 3118081 gacaatcgtc gttctgccta tatgaacggg ctcggctatc gcctttaccg ttccttcctt 3118141 tacagatttt aaatggttgg cgttaatctc caaaccaaca caagcttgcg ttgtatgatc 3118201 aatcaggttc tgtgcacctg cgctcgccgc ggtttccgcc agggccactg aagcgcctcc 3118261 atgcaaatat ccgaacggct gtaccgtccg atgatccacc ggcatgaccg caacgcatcg 3118321 ttccgctgtg ttttcaacaa tctcaatacc aagcgcttca agcaatgtgt gcttcatatc 3118381 catctctaca ccccccaaca tttaaagtac accgtctgat ttcgcaatca aaaccgcttc 3118441 cgtccgtgaa ccgacattca gcttattgaa aatcgatgtc aagctgtatt caatggaccg 3118501 cttgcttaaa tgaagggcat ctgcgatttc ttggtttgta aatccctttt caacttcttg 3118561 aagaatcagg cattctctag gtgtgagcac atcttgttct ttttgagagg aaggagccgg 3118621 ctttgttttt tgctgagtca tcagctgttt aaagtaagca aaatcgacta aaatttctcc 3118681 gttgagtacg tggtatatgt attgggtgat cttttcttta gattccgttt tgctgatggc 3118741 accgtgcaga cccgcacgaa tcgcttcctc gaaataatcc tcgacctcat aaccggtata 3118801 cacgataatt ttacaatgag gattctcttg taaaatctgt ttagaaagct ccatcccatt 3118861 gacctcgccg cctagattca gatccattaa aatgagatca tatgacgaga aatcatgctg 3118921 cttgataaac tgttcgctcg gttcaggact gagacaatca acagacaaat tcgaatccgt 3118981 ttccaaaatt gtcttggtgc cttccatgac agccggatgg tcatcaatca ctagtatctt 3119041 tttcatgttt tcctcccttt tactcactct tttccatttt ataaaaaaga cttggcctgt 3119101 gccaagtcgt ttccgttata aatccattac aattcgattt caatatcagc cttaaagccc 3119161 tttccttcac ttgtttcaat ccgaaggcgc ccatctaaag ccctgactct ctccttaatg 3119221 ccagaaagcc ccatgctcat ggaatgctca gtattttttt cttgatcaaa cccaacgcca 3119281 tcgtcctcat aatgaagaac gattttgttt tgaatactga tgagcataat cagcacatcc 3119341 gtcgcctgag agtgcttgac cgcattagac agaaactctt gaatgatccg gtacaaattc 3119401 agctgcgaat ccagatcaag ggaagccgta aatctcccgg tatttaaacg gatatgaaac 3119461 ggaacccgct cctgctgctg cgccaccagc ttcgacagcg ccttcaccaa tccaagatca 3119521 tacagaagct gcggccgcag ctcatgacac gtctccctcg tcatcgaaat cacatcagac 3119581 atctgctcat tcatctgtac aagcttgtcc tgcacctctt cacggcacgg attatcatcc 3119641 ttcttgaaat cacccaaaaa cagctcacac tggcgtttta aggaaatcaa atcctgaaga 3119701 accgaatcgt ggagatcgcg ggcgagtcct gaacgctgtt tttcttcgat tgcaaacatt 3119761 agctttttca gccagatggg gttggttccc tcttgtttta agtccttcaa atgttccatg 3119821 agctcctcaa tatgcaggac attttccatg gacacacttg tataaaaaga cagtgttttc 3119881 agccacgata tttcatcacg tgttagccgg ggagtgttaa tattagataa acaaagcaga 3119941 acataagaac taccgcctcg ttcaccaact ttcataagaa agccttgatt gacttctata 3120001 attttcccaa tttctgaagt tacgttttca aattcctctt gataaaaatt ccagtccggt 3120061 ccaacttcat gcttatctaa aaatatcact ttgtgatcag gagtaacctc aaaggtataa 3120121 gctttgctta caagcaaaac atccagtata gtatttttca gttctttaaa aacttgttga 3120181 agagaagtta cacccctcat tagctgagta tatttaaaaa tactgtcctg atagttgaat 3120241 ttttcggaga aacgttttaa ccgaaattta aaatccatga cctctttaaa ataaaagaca 3120301 gcgaacatga caacgaaaaa aaatacagtt tgacgcacag ggttcatctg gatgtccatt 3120361 acatcaaaca gaactaatgc accaactatt agaagagttg gtatcatggc aagtagagca 3120421 tagtatctca ttcttcctaa gataaactct atatcaaaca tcttattggc tacaaattgg 3120481 tatactaacc cgaacggaat tagtactagt aatgacgccg aagctaatgc cgggaaaata 3120541 taattacctg taaatattat tggaagaaca aaaaatatca aaaaaggcgc aaatgaaaga 3120601 gtgtttgtta aaattagtaa tttaagaata aacgaatgct cagcatattt atatttatta 3120661 agatgtaagt atatcgctga aaaagaaaat agagtcaaag ttgcaaaaga aaccaaatta 3120721 agagttgcta aaaaatcaat atctacttgt aaatagtctt gaaaaaactc aataccaaga 3120781 ttaaatattg gtatgatata aagaaaagaa attctattca aaaaagtttt acctatttct 3120841 ccaaggtatc tttgtataaa ttgaagataa agaataggag aagatataaa agtaaacaag 3120901 ttaatatacc gattgattat atgtcctcta aatggtccgc ctgcacttat atatgctatc 3120961 gaaatgtcta ataacaatag aataagaata taggcagcaa atgatctcct ttttttattt 3121021 actttaagta tataaaaaat acatattatg cttaaaaaat aaaaaaacaa aggaagtacg 3121081 aacagaaaaa aactataagg tctatttaga gtaactaaat caaaatcttt gagatgaatc 3121141 ttttttccac ttctcaaaat atccagactg ttaatatgac tcaaatatcc ccatttcaaa 3121201 tgtttgtctg aaggtttttc tttattaatt tttaatatga tgtctccctg tctcagacca 3121261 acaaattgtc catatgaaga ttccgatatt tcttctatca taaattgact tttatcattt 3121321 ttatgaatct tagtcccaat aataattcca ttcatactga tataagttgt atagcttata 3121381 taaaggatac tcaaaacaat tacagctatt gtgaattttt ttattaagtt cttcaatatt 3121441 aatccaccta ttaatcaccc cattgacggg ttattggatc agccagataa taatcattat 3121501 aagctttaat tattgtttca gtttcttgca catcaaaacc tataaggcag gcttctttat 3121561 ttttcaattt ttttaaagcc tcaggataat ttaaaaagta gttaattagg tcttgcatct 3121621 tgtatccccc tttgtataac ttaataagca ttcctttatt agctcttttt tttctttatc 3121681 taaatttaat tgttctatag cagaaataca tttctgttta tatatttcca ataataccga 3121741 aatgtattga gtaactcccg ctttaattaa tttttcttgg aatttctctt tatcaagtaa 3121801 cgatttataa tataagtctt tatgtgaaat taagtataat aaatcttccg aagcatcatt 3121861 aaaaaggcgc ttaagatata agtaaatcag tgtatgtttg tttttttcaa tatcactgcg 3121921 atttccggat aaaagaacat aataatctcc agaaatttga gctataatcc ctttatagta 3121981 ggaatatctt tcaactgttt cattatattc tcctgtagcc aataaaacac ctgctacatt 3122041 tgctagtgca atcagacttc cacattttaa tctaattact tctaaacttt catcttctgt 3122101 tttagattta ttagtgatat cgtcatgttg accttgcatg gcctcgttta cgtattttaa 3122161 aacatattta aaaattagag gattgttatt taatgaataa atactcgtta atcctactgt 3122221 atacaaggaa agtgctgcat ttaacgactc cgagcgatta attttcatcc ataatgcatg 3122281 gtgattatct tcatcttcaa gatcatccat aatatctgat gaaagaataa gaatttctat 3122341 tcccgcgcca agccttgttg caacatctaa attctcccct ccaaaaacaa cataatgtaa 3122401 gattgtggat tcagcaaagg agaatgtttc tttagaatca ataaatgagt aaagaagttg 3122461 tgacaaatcc tcgttaaata tgttttgctc cacaatctcc ttcattttct ccttgatccg 3122521 gacagaatct aaacatatct gctcaataac gacttccccc ctcccattcc attttactaa 3122581 atgggacatt taaaggacag caggtttttc gttttttaac aatcatataa tactttatcc 3122641 atttattgta tcggtagaac gaaaaaaaag acttgtttcc aagtcttttt cacgaaattt 3122701 tcattgcata attgtattta tcgagttgat caatgctttt gttaatgttt cgtaatgaat 3122761 ctgtcgtttc tttaatatca agttcgagtc ggaataacaa ttgttttact tcttcaagtt 3122821 tcttttccat cgtttccaca ctcctttttt tgaaagatca atgaattgtg tatggtgaac 3122881 gagtcctagg tatttgatct gttactaata gtgtgtctgc tttcggctca tttttcaccg 3122941 aaaagtatgc aaaaaagtcc tgcgtgacac cgcaaatctc aataggtcct tatactcaaa 3123001 ggaatcacaa caagaacggg actatctttc tatgcgaaag agcgtttata tgtgctgaaa 3123061 ttgagaaaga ttcttaatct ccttgatttt aacgggtttc gcattttcac taagcaagac 3123121 tatagtcctt cataccgtat tttcaaaatt gaatatgcga ttcttggcgt ttcctgaccg 3123181 acaaacaccg aaaaagaccg caacgctaaa gttgtggcct tttcgctttg tcatattcgg 3123241 caattaggga tctatacata tagaaacatc cttttttgcg aggtgctccc atgagatatc 3123301 gttatccctg gttttacgtg tatccgtatg aggtacgccg tccgcccgct cctgccaaca 3123361 atattgatac ctttatccgt tcagcgaagc aggccgcagg gatatttgcg gatgcccagc 3123421 tcgttctcag ccgcattgcg ggctcgcggg agctttcgcg ccgcattctg accgcagccg 3123481 aacagtctga taaacaaact ataaggcgcc tgatcaaaca aatgggcgtc cggcatgaag 3123541 tggatacggt ctttaatccc gacggcatct atatcagcct tatcggaacg caaagccgaa 3123601 tgattcttgc tttgcggtgg tcagaggacc gcaatcattt tgcgtccata agattatgac 3123661 accattccag agcctctaaa taacattcat acgcttcttc tttgtccagt tgattgccta 3123721 attctgagca agtgtcccag ttgttgcttt caattaattt cacaagctca agcatttggt 3123781 agtagtcgtt ttgatggcct aataatgctt gcccgacttc atcttttaaa ggcaattctt 3123841 gaacaatttc ctctatttct ctatgcagga gggtgtctat gagagaaaac attccgatca 3123901 gcatataaga agcaggctgc ggccgggatg tctttctcgc cagcagttcg caaagctttg 3123961 ctcttatcag agaaatctta atgatttcgt gcttgctgga atgccctttc ctgcttaaat 3124021 ccttaaagga aagaatatat atccaccgtt tgatttcatt aaatcccagc agcataatgg 3124081 cctgttgaat gctttcaatt ttctggctca aacggctgtg ggatgagttt aaaaatttta 3124141 aaatttgata ggacagtgat aaatcccgct ctatgtactc tgtcacacgc tttatgttag 3124201 gctgctcttt actcagttcg ttaagcagtt catagtaaga atagaaatga gtcgataggt 3124261 catgcccgct gatgatgcgc ggctcgctga aaaagtagcc ttggaataat tgaaagccgt 3124321 cttggaccgc ctgtttatat tcttttcggg tctctacttt ttccgctaaa aaaatcaggc 3124381 cgcggcagcc gtaggtttgc aaaattgttc tgcgttccat tcgtgttgtt ttgagaaaat 3124441 caattttcaa tatatcaata tagctcatga gtttttccag taagtcctca tcttgcggat 3124501 ttattgcata aaaatcatca agcgccagca tataccccat ttttttcaat tctttgcatc 3124561 tagaaatgag ggccggcgtg atcggtatat cttcaaggat ttcaatgaca agctgtttcg 3124621 gattgaagga ggtgggaaga ttcgaaaaca tcaggctttc cgtaaaatta acaaaacagc 3124681 gtttcccttc cgtcagcttc tcaattccga tgtttaaaaa gctgttgatc accaaatctg 3124741 ttgttgcctg atcgccgtct ttagcgctat acacgttctc ttcgctttct ctatacagca 3124801 gttcataagc aacaacctgt tcttttctat taaaaatagg ctgtcttgca acaaacaccc 3124861 tcattgattt atccccctta caatacgcgc ggctttcacc cctaagtata tcaaataatt 3124921 tgacgaaaat tgtctaaaca tgaaaaataa tatatacata aagaaaactg gcccttcgcg 3124981 aatgaaaggc cagtttttct ttattcttcc tcaagctctt cttcaattct gcttttcact 3125041 tcgtggatcc gctgcatttt attgctccag cagtcctcgc ttaaatcaac cgggtattcc 3125101 tccggcttgc tgattctctt atattcctcc caaagcaggc tgaggttatc ctgcacatac 3125161 tgctgtatgt ctgaaatctc agggttttgg tagcaaagaa tacccttctc aaaaatcagt 3125221 tcatgaagat ccttcgcata aaaattcgtg acaaatttgc tgatgaatgt atgaaccggg 3125281 tggaacattc tgagccgctt ctgatcattc acctgctcat cataaagcgc aatatagtcg 3125341 ccttcagaat gatggttgga ctgattaata atgcggtaga ctttctttct gcccggtgtc 3125401 gtcacttttt caggattgga cgaaattttg atcgtgtcga ccattttccc gtcttcttca 3125461 atggcaacga gtttataaac tgcgccgaga gccggctggt cataggcagt gatcagcttc 3125521 gtaccgacac cccagacatc aatgcgcgct ccctgagcct ttaaattcat aatggtgtgc 3125581 tcatccaaat cgcttgaagc aatcaccttc gcatctgtaa atcctgcttc atcaagcatt 3125641 ttccgggctt tttttgacag gtacgccaaa tcgccgctgt ccagacggat gccaatgaaa 3125701 ttaatgcggt cgccgaattc cttggcaacc ctaatcgcgt tcggcatgcc tgaacgaagc 3125761 gtgtcatacg tgtcaactaa gaagacgcaa tccttatgtg tttccgcgta ttttttgaaa 3125821 gctgtatatt catcgcggta agcctgcaca agcgcatgcg catgtgtgcc ggaaaccggg 3125881 atattaaagc gctttccggc tcttacattg cttgtcgcgc taaagccgcc gattaaggct 3125941 gctctcgctc cccacatggc cgcatccatt tcgtgcgccc gtcttgttcc gaattcaagc 3126001 gcaacttcat caccgatgac gcctttaatc cgggcagcct ttgttgcgat taatgtttga 3126061 tagttcacaa tgttgagcaa agctgtttca atcagctgcg cttctaccag gggtgcctcc 3126121 accctcataa tcggctcatt gttaaaaacg agttctcctt ctttcatgga gtaaagtgaa 3126181 cctgtaaaag ataagccgcg caaatattca ataaaatctt catgataccc gagttcatcc 3126241 tgtaaataac tcaaatcgct atccgtaaac ttgaaatttt ccaagtattc aatggctttt 3126301 tccaagcccg caaatacggc atagccattt tcaaacggaa gccttctgaa aaacagctca 3126361 aaaatcgctt tcttttcatg aatgccgtct ctccagtacg tttccgccat attgatctga 3126421 taaaggtctg tatgtaatga caggctgtca tctttaaatc cgtactctaa cactgttttt 3126481 ccccttcctt actctgccac ttgcgctccg atgctgtttg caaaatggga aagagcccat 3126541 gcgtgcccct cctgattaaa gctggcaaca gcttgtttat gcacaacaat ccgaaaacct 3126601 ttgttgtatg cgtcaacagc tgtatgcaac acacaaatat ctgtgcagac accggcaaga 3126661 tgcagttcgc caatctgccg ctctctgagt ttgagctcta aatcagttcc cgcaaaagca 3126721 gaatatctcg ttttttccat gtagtaaaca ttaggttcat gttcatgttt ctgatataga 3126781 ggcaaaagct ttccgtacag atcttttcct tccgtgcctt ttatattatg cggaggaaaa 3126841 agacgggttt cagggtgata ttgatcccct tcatcatgag aatctactgc taatacgacg 3126901 taatcaccgt ttgtgatgaa ttctttagtt aaattgacga tcgcctcttc aatcattctg 3126961 ccgggctccc cgcaggtcaa ttttccgtca ctcgccacaa aatcattcgt ataatcaata 3127021 caaataagtg cttttttcat agccggcctc cccgccatca gtatgagaac attatatctt 3127081 atctccagtt gtaagtgaat tgccatgaac aaaaagacaa acggtccgtt tgtctcttac 3127141 gatttcagta ctgaccgatt ataaatgtcg tcctgaatat atatcaattc acgattcaca 3127201 gcgatatcag ccgcaatgac gatgcctaag ggcgtatgaa actggagatc agatacaatc 3127261 ttgaaaggca ctccgtaccg gctcgccatt tggatataag aagagtaaga ctgatactga 3127321 agctctccat taatcaaaag ggtgacgtta tggctgtttt tcagctcgtg ctctgcctct 3127381 ttatacggtt tgcttctaag cacctgtcct ttcgtcagtg ccaaaacgac tctttctctt 3127441 aaagagccta aaaacaaatg gcgctcgtca ggctttgtct ccaaaggccc atacattcct 3127501 tgctgcaaat agagatccat tttatcttca ctcaaaagcc tgtcctcccg tcttgtttgt 3127561 cttcattatc acctgatcag gcaggagcta aactttcaag cgccgtttac atttctgtta 3127621 cccaatgaat gatttttttg gccagctcac cagcaggggt ttcctctgta tgccggcgca 3127681 acgacgcttc cagccgttca ggcagagttg ctttatcttc ttcataggaa atgatcgtgc 3127741 tccactccag ctgcggtacc gctacaagcg tgcgcagttc ttttctgttt tcatgcagat 3127801 acacgtccgt gatcattccg gtttgcgtat tgatatttgc ttttctgatt ttcataacat 3127861 gacctctcta ttcaaagact acccatatta tacaataaaa aagcaacagc ctcttgtgaa 3127921 aaggctgtta cccgttaaac gaaactgttt catcagtgat atcggcatct ttgaagagag 3127981 ttttactcgt ttggttgtta atcttcacaa aatcaccaag ctgaaatgtg cctgaccccg 3128041 cccctgaatg agcgacgctt ttgggcgaaa tcgcaaatac gtctccaaag cttgccgcgg 3128101 cattatccgt aactgacatg atataaatcg gccccacaat tgcaggcatt tccccacctc 3128161 cgcattgatt tacagcatca tatgcaagga gccgataatg gtgcccgcct attcagctgg 3128221 ctttgcgttt tcctcgagtc gtgaccgctg gcgcagcttg atcaagcgga caatattcag 3128281 gaagaacgcc ttcactaccg cataaaccgg caccgctaaa atcatgccga gaattccgcc 3128341 gaagcttccc gctccgatta atagcaaaat aatcgtaagc ggatgggtat tcagccgctt 3128401 tccgatcaca agaggagaca gcaggtttcc gtccagctgc tgaacgatga cgaccacaat 3128461 aatcgcaaac agcgctttgg ccggcgagtc cataaaaccg acaatgacag ccggcgcggc 3128521 accgagaaaa ggcccgacat agggaatgat attggtaatc gccatgacaa tcccaagaat 3128581 cagggcatac ggcagtccgg caattaaata gccgataaaa cacgctgttc cgacaaaaag 3128641 acagattaac agctgcccct ggaaatatgc cgcaagcgta tcggataaat ctttaaaaat 3128701 ctttaagcct tctgtccgat aagaagccgg tagaattttt actgccaaat gcggaaagcg 3128761 gtgtccgtct ttcagcatgt aaaaaaggat aaatggaaca gtaataataa caagcgtgat 3128821 gtttgtcacg acaccaaaca ccgcagataa actggacgtg atattttgcg gcaggttttg 3128881 gagaaaactt gtcaatgact gttcaatttt tgatatcgat acataatcct ggttcatcat 3128941 ccaggtaaac cattgagaat gggacaaatc ctttgtcagc gcctgaatct gttttatata 3129001 atcaggaagg ttgttaaaca gccctgtcac ctgtgcggtg atgataggtc cgactgacgc 3129061 tgaaataaag gcaagcaaac cgataaacag taaatagatc aatagaatgg ataatgtccg 3129121 cggaattttt ttctcaagca ggcggacgac cggattaaat atgaaataca aaattcccgc 3129181 aattagcatc gggaaaaaca atgtcgagat aaaaacaata aacggctgaa atacaaatga 3129241 aacttttgtt gctacaaaaa taatcagcaa aacaaataaa atctgcaatg tccaaaaatg 3129301 gacttttgat ttcaacaagc tttgttcctc ctagtttttc tttgtctgtc agataaaaga 3129361 acttataccc catcattgta acaaaaatga actcatatca gaactcttaa tataatgaaa 3129421 ggagtgttgg tgatgaaggc cgtgacatac gatacagatt cagaactggc ttatatctat 3129481 gttcttcctc cgaaaaagaa caggaatgta cggactgagg agctcagagt caatgattgt 3129541 ctcctgctgg atatcagcca agatggcaaa atcgccggat tcgaatgttt tggtgaggca 3129601 gcacacctct gtgccccatt tgccgggaaa tcccggctgt atgtaaaaga ttcagacggt 3129661 tatcattttc gggtctgcca gcatgcttca gtccgttcct gctatacggt gtaccgtgtc 3129721 actttctgtt tttcagatgg tgactatcag gaatttgccg gctttgacct tgatggaaca 3129781 atgtatcata gtgcgttttt acagcgctta actgaaaaat aggacgtcct gttgtacgcc 3129841 tatttttcat gcgcaagcac tgttagaccc gctcactgta atctggggtg acggaaatca 3129901 tgtgctggat tctgatcaaa caaacagaat ttcgggctcc ttcaattgtg atatggtcag 3129961 gttttacatc gatcagtctg cctctgaccg tatctcgtac tgtctgtata acgaaccttg 3130021 agccgatgag ctttttaatg gtctgataga cataaggatc gactaaagag accagttgcg 3130081 gactaccttg gttgaccata cttttatccc ctttgtgtgt tttatctcag cttatgccgc 3130141 gcttatggat aatgacacag gcttacctga taaaacaaag gggtgcggag attttaggag 3130201 aatacgtttg gaggcgggtg taaaggaagt atcgatgaag cggagacagc gaagaaagct 3130261 ggcgctgttc cgtacttata caggctttat cacggatgcc tgggcttggt cgattaattg 3130321 gtccagcttt tctatttttt ttcgtgcggt tgaaggatca atttggcggt aatgatggtg 3130381 gccgcccggc tcttcatcca gttcgtccgc ttttttgaca atctgctgca gtgtgttttt 3130441 atctaattcg ccttcaggca aataggaatc tgtatgaagc aaaatggcta gtgcaatctc 3130501 ttttgctgct ttcggttcct cgccaagccg aatcagaagt ttatgcgccc gttccgcccc 3130561 tttaatggca tgaatgtcat ttcttttgta tttctcataa tcccactttc cgtctgtata 3130621 ccattcataa tggccaatgt catgaagcag tgccgctttt gctgctaaat caggattaat 3130681 gtcagccttc acagacagcc tgtatgcatg ataagcgcag gcaatcgcat gtgccacgcc 3130741 ggaacgctga agatattttt gtgcaattgg atgggtgaaa acatccatta atgtaacctt 3130801 tctcatggaa acccctcctt tagatatttt tagaatccta acataatttg cagagaaact 3130861 caattcttat gtcacatcat tttgatcttc ttatcatcat tgttataccc taaaagcaac 3130921 gtttcagtca gtatatgcgg ctgttcaata aaatgcgctg gctgcagcct tttgtataaa 3130981 aaaaagagca gaaaatatct gctctacaaa aactctttaa tatcataaat gcggccgttt 3131041 tccgtccctt tttctagtaa agaaagcagc gtgccggcaa taaagtccgg actgcgaagg 3131101 cttcctgttt catttaattt ccggaatcgt tcaatgtggt ggaaatcctt tttcgatgaa 3131161 gaacggatga cggcctgcat ctcagtgtcc atcactccag gtgagaacga aatcatgttc 3131221 accggcagct cttcatcctc ctgttcaaat ccgaatgtcc tcgtaaacat gtcgagcccg 3131281 gcttttgaac tgcaatacgc gctccatccc ttatatggat ttttggcggc tcctgaagta 3131341 atgttgacaa ccgtcttttt gccgctgtat gaagcaaacc gttttgtaaa cagctgactc 3131401 aaaagcacgg gcgcagtcag gttcagctga taatggcgct gaagctcgtc aagagacgct 3131461 tcgccggcac gtttgatcgg cgttaccatt ccggcgttat taataagggt aataccagaa 3131521 taacgatctg aatcgatgga tgagagcaat gtttcaaatt gctgttcagc ttcttcgaga 3131581 ttgatgaggt ctatttgatg ctgcgttagt tttttgtgag agacatctgt tttcgttctg 3131641 gataaggcat ggacttcatg ccccttttct aaagcctgta atgcaatggc ttgacccagc 3131701 ccttttgacg ctccggtgat gatataaagt tccattggaa acctcctttt ccgttattat 3131761 tgtacggcac ctcttttaca caacacaagc acgcggccta cgccttcttg ttttcctgcg 3131821 ctgtgacttt tgggatgagg aacacgatgc ctgcaattcc gagcaggatc agtacgacat 3131881 agatcatcgg cagcagcaat gatgatgttt cttgttcatc ttctgtttcc gttgatgatg 3131941 tctttgtcat tggtttttca gcaaaagtaa ttccaagctg tttcgactgg gccgcaatcg 3132001 tgttggaatc ctcggcattt gttgatgtaa acaaatcttt tatcagctcg gcgtccttgt 3132061 ccttcggttt atcaaaagtg atatcctttt gttcctcagg cagttctgtt ttttcttcat 3132121 agtaggtatc ttcatgcaaa taattcgtat cgatttcgat gtcttttttc tcatactggt 3132181 ttggcgcgac atctgtattt tcttcagttt gggcagccgc tgcagagggt atgaaaaggg 3132241 aaaaggagag catacaaatc atgatcccct tttccatgct gcgatcacgc ttcatacgtt 3132301 tcatcgcttt ctgctgtgtg ttcagccatc aaccggataa tcagcggcag agccacggca 3132361 atcaccgtaa tgatcagcag aactgttatt cccattgtaa acaagtgccc agtaccgtac 3132421 tggatgtcga tatatacttt cgaaaccgga tcttcaaatg taaagttcgg catgatcaaa 3132481 tcaataagcg gtgcgacata gaataggatc attgctgctg aagcaaccca gccagggatt 3132541 gatccgaatc tgaatgccgt ccggatgaag gcagagcttg cgaccagcaa tagaatcgta 3132601 aacaccgacc acttaatcgt ctgatcgtcc ggcagtgaat aaatattcaa gccgaacaag 3132661 ctgatcataa gtccgacaag gatattcaga attccgaata acgctccttt gacgagaagc 3132721 ggtgcgtttt ggtaatacga gctgaaatag ccgattaaca gactgctgat caacacaatg 3132781 acaaggatga caaccggagg taccgtctga attttttctt ccggaacctc tccgctgatt 3132841 ttaagcggat tcgctaagta atcatataca tagccattgt tttgcccgtc tactaatgta 3132901 tttccgagta tgccgtatac gtcatttcgc acgagtttcg tggaggcgac atttttcccc 3132961 cagttgttgt ttaaggtgtc ggctttcgct tgaacatcat taacgctttg ctgcatgttg 3133021 gttgtgtaat caatgatgcc ggactggcga tcagacaatg aacccatcat gtctgacatt 3133081 tgcagcactt cctggccgac cgtatcttgg acactcagtg ccatggtacc agacagccca 3133141 tcgttgctga acgtcgcaga ttcctgtgtt gcgcccgtta caagctgttc tgacgctttt 3133201 gcggcacttt cagagatttt cgtcagttcg tcgagaacac ctgcttgaga gtcacggata 3133261 tagccgctgt agtcgtccgc aaatttggtc atgccgtcga tgaagctgtt aatatcctca 3133321 tctgtttgca tcgtgttgtt tttgagagct tcccagctgg ctgattcttc aggtgtgaga 3133381 gccaggactg attggacgtt gccatcttgc tcttggatga cttcaccttt aataatagtc 3133441 aaagagccta gatccagatt atcatttagc gtagacttat ataaatttaa agagttgtaa 3133501 tacttcatca agttagaaat attatcagtt tcaattctac ttgaaaaaat tgaacttagt 3133561 ttttctttct gatctatata gcctctactc tgcaaagttt gtattatttc gtcttccaaa 3133621 ttgtatatta acctataagc atcattgaca ttattatcaa aatcaaccaa cttttttgtt 3133681 aagtcaccaa tttgatcatt taattttgaa actgttttat ttaactcttt aatttcttga 3133741 tttaactcat caatatgttt ctctagtttg ttgttatgtt cctcttgttt ttcttgaagt 3133801 gcattttcta tttcctctaa ttttatcgct gcttcgttca gacgtttttt tgcacctgaa 3133861 atatcagttt caccgtcagc tccgtcaccc tgtagcccat cactttgatt tgagccatcg 3133921 ttttcatctg cgagttcaat caaagagaaa tctgttttag aggttcctgt attctccgtg 3133981 tttgtatctt gttcaggaac gttttttgaa gattcttgat gtttttgtcc cgtttcaatg 3134041 ttagtttgaa catcattttg tgatccatta tcttgagtac cctcttctga tgagccagta 3134101 tcttcatttg ttggctgatc atcggatgtt ggaatatcat tcgacggttc ttcagtatta 3134161 ggagaatcat cggttgatgg ttcttcagca tcgggtgttg ttggtttttc ttgttcaggt 3134221 tcttttaacc cttcagagat atctttaatt tcagttgcaa catttttgag ctcatcccgc 3134281 tgcttctcta aatccaattt tatatcttca atatcttcct tatctgtgtc atctttatta 3134341 tcagatgtgt cttctccatc ttccttttcg tcgctttcct taggtttaag taaactaagg 3134401 cggttcttcc cgatattctc ttgcaattga tttaaatttt gatatttaat agcttcatat 3134461 tgacttttat atcgagatag aaatgcatta aacatgtcat tctcaatttt tttcataccc 3134521 atttcttgca atggcacttg attttgcctt aacttttcag cattgttcaa cgcaaggttt 3134581 gtcagtccta tttgtgtctt cgcttggccg atcccggttg ccaatccgct catgcgttcg 3134641 ctgaactgat tcgccttttg ctgtgcctgg atggcatcca gacctgtccg gatttgctgc 3134701 tgtgttgaat cctgggctgc caaaagcagc tttttctgat tctcttgata ttctttgtac 3134761 ctttcaactg tatcaatgaa ttctttcagc gtgtttttgg cttcctccgc cgtagaagct 3134821 ttttcttttg tcgtgccttg cgcttcattc attgatttct tcagctcatc gattaagtct 3134881 ttttgctgtt tgatttcacc tgctaaatca ttagagcttg gtttgtaaaa gttgtacatg 3134941 acattctgga attcagattc tttattgacg atcttgtcaa attctcctct gatgttgtcc 3135001 actttttgcg aaacaaaatt ccagtataag gccgacattt ttttgttcat tgtcttttgg 3135061 gcatcctcaa gctcacgctg aactttttct ttgttaaccg cattcaggtt atcttgaatg 3135121 ctgaattcga gcgttgcctt ttgaggatgg tctttgtcat agctcaaaat gttttttgag 3135181 aagtctgagg gaatgtagac aatcgcatcg tatttctttg aagcgagacc ggtctcggcc 3135241 gcgcttcggt ttacgaccgt ccacgaataa tcaggacgtt cacccagaac ggccgctact 3135301 tccttgccga actgggcgga tttgtcctct tcatcagact ttacctcatc actcaatacg 3135361 cctgtgtctt cattcaccac cgcgatttgc cgggtagaat tgactgcttt tttcgttggg 3135421 tcgtctccga taaatcggaa aaacaacacc ggcagcagca aaatgatgat gacggcggat 3135481 attaacttga tcaagctttt tcgttgttct gtcatctagc actctccctt tcagcagaac 3135541 ataaaggaat ttgaactttt tgctccttcc cgttttccac aacatatccg aagcccggct 3135601 gaatctcagg ctcctgtctt tggtacggga gaggaatgac attttgctca gactttttca 3135661 tcagcagaat cgcgtggcgg atttgcttca tctcagtcgt caaggagtca tagccttttg 3135721 agaattcgct gtggtttccg cccgggataa agctgaaccc aagatgagcg tatgatttca 3135781 tgaagttagc gagacgatct tgtattctcg tatcaatcgt ctgctggaat ctcgttatcc 3135841 cgtcaatcat cagcacgact tgtgagaatc gcagattttg tgcgtctcct tggcggacgg 3135901 cttctacata catggcttct cttgttttga aaatgtcttc tgctgtttca atccactgct 3135961 caatatcttc tttcgtttcc aaatatgaaa catctgattc cttcgcataa tgagataagc 3136021 cgcggtcaat cgagtcaaac aggccgatca tttcggtttc atcatcaatc agatgttcaa 3136081 gcatgacttt taggacgttt gttttcccgc gctgagtttg gcctaaaatc aggcagtgct 3136141 tatgcttgcc caaatcaaaa tagactgggc tgactgtttc ttcatgaagc ccgatcggta 3136201 cagataaagg cttgcgttcc agcttgaagc ggatagacaa ttctctcgtc gacaagctct 3136261 caggcagcat cggaatcggt gccggctgct ccattgaagc aaatcgccct tgaagtttct 3136321 gtacgtctga tttcagctcg ttgaacatgc cgatatcatc atcggcgtca acaggcagga 3136381 acatttgcgc gaaataaagc tcttcctttt gaatgatgac gcgtcccgga atcggctcaa 3136441 gattgaattt cggacggccg taaatggaat atccttctga ttgatccatg agataatgga 3136501 caatctttgt tttcaagtta tttaacaatg actggcggac agcattcacc cgcgttgctg 3136561 tcagcataaa gtagataccc aagctttgtc cgtctctgga aagctggaca aattccgatt 3136621 caagctcatg catctcatcc ttgacaatgt caaagttgtc aatggtgata aaaatgaatg 3136681 gaagctcttc ttcgctcagc gcattgtaca ttttgatgtg gctgatttct ttttcccgga 3136741 acaaacgttt acggcggtca atttcttctt tgatgcgaat catgaacttt tcaattttcc 3136801 ttgactggtc catcaggaag taatccgcgg tatgcgggag cttcgctaat ggcagcagcg 3136861 ttccgtttcc gaaatcaaag atatagacat gaagctcttc aggtgtgtat acgtccgcaa 3136921 aactcatcag gaacgttgcg gctgcaatcg attttccgta gcccgaagag ccgaagatgc 3136981 cgatatttcc atcttccatc atcttataag caattggcgc ctgtctttgc agatcaggtt 3137041 catcgacata cgcaaagtgg aaatggtctt tttcgtttga agggaaaaga gtgcgcggaa 3137101 tacgttccgc aagcggcggc agccaagggc ttggcagctt ctcgattccc atttcatctt 3137161 ggatgcgttc aatttcgtca actacagctt cgatttcggt ttgaacgtct tttttcgcgt 3137221 tatcttcggt atcaacctca gaaagcggga tcagacccgt atctgtgacg atcgcgattt 3137281 catcctcggt accgtagact tcctctaagt aaggcgcccc gctccatgca gattggaaca 3137341 gctcatacac ttcattgttt ccgacctgca aatagccgcg gcctgttacg gtaatgtttg 3137401 cggcatcgct gtttttcaaa atttctttac tgtcggtggc atcctggacc ttgagcgcta 3137461 ctttaaagcg cgagttactc cagatctggt cgtcgatgat gccgcctggc ttctgtgtcg 3137521 ccaaaatcaa atgaacgccg aggcttcgtc cgatacgcgc ggcactgaca agctccctga 3137581 taaaatcagg ctcctcgctt ttcagctcgg caaactcatc agaaattaag aacaagtgag 3137641 gcatcgccac ttctgctttc ccttgcttgt atagctttgt atagtcattg atgtgattga 3137701 cttgatactg gtcaaacagg cgctgccttt tttttagctc gcttttaatg gaagcaagcg 3137761 cacgcatact gaagtttttg cttccttcaa tatttgtgat cgtgccgagg aggtggggaa 3137821 tgttacggaa cggctgcgcc attcctccgc ctttatagtc aattagtaag aaagccgctt 3137881 catgcggatg aaaatgcact gcaagtgaca agatgtaggt ctggagaaat tcacttttcc 3137941 ctgatcccgt tgtccccgca agcaagccgt gcggaccgtg tgctttttcg tgaaggttca 3138001 gatacacaat gtcatctttc cctttatagc cgatcggcac tgacagcgac ttcgacgatt 3138061 cacttgtcag ccatctttgc tgaatgccga tttcttttac ttccttcgca tgaaaaagct 3138121 ccaggaacga taccgtttcc ggaatggaat tcgtaatgcc gacctggtgg ttcagcgtcc 3138181 gcagtgtgcg tgaaaaccgt tcgttatcct cacgctgatg atgatcgaga cggaacggaa 3138241 ttcttaccgc ttttttcttt tgtattaaaa tgtcgccttc atgctcatta atgtagcgga 3138301 caagagttgt aatgttttcc gacaagcttt cctttgtttc tgcagcgaca attgtcgaga 3138361 tgcccagatg ctcatgctgc ccttctaaat attcgagaat gacatgctca gagatcagct 3138421 gctgattcgt gatgacaaat acaaaatgcg gtttgaactg cagtttttct ttgtcatctt 3138481 cgagatcacg ctctctgatc aattcgtaaa gtgaagacag gagctgatct cgggtttgct 3138541 cattataaat aaatcctttt gcataaatat ggggcatttg aaattgcgga agccacttca 3138601 tccactccca gtctttatac tcttcttcat gaaaaataaa tacgaaacgc aaatcgtgat 3138661 agctgttaaa gaacgacagc tgtccgatta gctggtgaat ctcatttttc acaatttgtg 3138721 atttaccgac aagccccatc ggaccttctg ccaaatcgac cgtcaccggc gcattacgga 3138781 tatctttata gacgcgttgc atgtgctgcg atttctccat gaggtcatcg atatcacgat 3138841 tcgccaagtc tccgccactc atattgattt catagcttga cggaactgtt cccgtcccaa 3138901 gccgcagctg gagataatcc ttgctttcaa gtgatttttc ccagatccgg tcactgattt 3138961 cacttgttaa gtatttcatt tgttcaaatg aaggaaagtg aaattcaaga acctgctttt 3139021 gcttttcagc aagtgcctga agctctttcc gcttattgtc taagtaaagc ttatatacac 3139081 gctcccgttt ttcctcgcgt tttttccgct ggtttttatc acggaaatat tgcactgtcg 3139141 aggtaatgag agtcatcata aacatcgcca aagaaacgag tataaatatg ccgcgcggct 3139201 ggatgatggc aactacgccc atcacgatca gcatcacaag cggaggcagg atgacgagcc 3139261 acagccctct gttggtttga tcgctctcct gagagggaaa actgaaagaa acgcggtcat 3139321 ccggcagatc gtataccatc cgcggcgttc ttctgtactg cggatatttt ttctgcatct 3139381 ctgtactcgg tttgaccgtt tctgttaacg ctgtttcaaa ctgggcataa tgaacaattt 3139441 ctaaaaggtc ttgttccgtc accctcattt gcgtgaagtt ccagaatatt tcatcccccg 3139501 gcttgagcgg cgtattggcg ttgattttct ctccgttcaa gaagatcgtt ccgctttcag 3139561 ggcggaccga ccagctgccg cctgcacgga gcaaagaaaa cgtgctttgt tctgcaaatg 3139621 caaaatcttg cggattcaga taaatatctg cattcgtttt ttctgaggaa catacaattt 3139681 catcccgatt tcccgtaaaa taaacggatt tctcaggttc actgcccgtc aatatcaagc 3139741 gtatatcctg ctgatccgtt tggagagtaa atgatatatc cgtctcaatc gtgccgagac 3139801 aatcatttcc caggaaaact tcgtattggc cgccggattc ctttctttta agagaaatca 3139861 ctccgctatt aaatggaatg gtgctgatcg taacagaatc cttcacatca ggccctatgg 3139921 tcaccggatg agacgacggg aggttagaca gatttaattt ttgaacgtta ttttggtaaa 3139981 aaacccataa tagactcaaa tggcgaaccc ccttacggcc gaatggcagc atgcgatgac 3140041 ctgcgcttca tgtctcacgt tatttgtcat cttttttctc atctttcttt tctgtttctt 3140101 ttttctcgtc ttctttttcc ttctgttctt cttttttcgc tttttcctcg gctgcggctt 3140161 tttcttctgc cgctttctct tctgcttgtt tttcttcgtc tgtttgtgtc tgttcttcgc 3140221 ttgtatcgac taacgatgtt tcagaattag actgtttatt ttcttgacgt tctttttggg 3140281 ctttttcaag ctcactattt actgaatcaa gttctttttg tatgtcttca tcatttgtat 3140341 cctcagataa aagctgctgt ttatatttag ctagggcaaa gtaaatataa tcattgtatt 3140401 ccagcttacg gccgatactg atcgcttctt tgtattctcc tcgaccataa tcaatccaat 3140461 ataagaaatg ctgagggtct gattgaaggg tgactaaatt attttctata tttttggttt 3140521 ttgcactccc caggttttcg acctcaacat aggacgtcgc cagctgatac tgcaccgatt 3140581 caggcaggct ttccgcatcg tacttggaca gtgtgctgat gacttcactg tactgcttgt 3140641 ttaagaacgc acggttgctg tccactatcg cctggtgctt tggctgcgcg aaaaataagg 3140701 cgtacatcga ataaataagt gccggtacaa gcaaaacaat gagccccagg ccgatatatc 3140761 gctggatgtt ccacttcttt ctcgggatat gtatgtatgt ttttgctttg gcttcgagct 3140821 catcaatatg ggtttgaatc agctcgagca aatcatcata ggattcagca tctaatatcg 3140881 cctttgcctc tgcggagaac gtcagcgttt cattgaattt caggtagtct tcaaacgcaa 3140941 aagcgccgtc aactgccaaa gccgctgccg ctttcagctc ctgccatact ctttcctcat 3141001 cacgctcgta aggaggaatg ctttctttta ctccataatg gagaaaataa ggcgtaagcc 3141061 ctttatcgaa tacaatgttt tcaggagcga caatcaaatt cagcctcgac agattgtgct 3141121 gctgtacggc ttgaacaagc tgataggcaa actgccattt acttttttta tccttagctt 3141181 tcatgaagcg gaatgcttta taggaggagg gaggttggat tgtgatgatt acttcatcat 3141241 ccgtcacatc gatttcttta tgaaaaaatg gatttatatc tttgatcacg ttagcttcaa 3141301 gaccgtcgag aagctttatt ttttcccgtt gaaaggtaaa tgtatagccg gcatctgttt 3141361 tctcggcaac agcttctaat tggttttcta aatatgattt ttgttcacct gacattcaac 3141421 cagatccttt cataatattt caagccggtc tccgtttgta atgccgcaat cagacagctt 3141481 gcattctccg gaaaacacct tatccttgtt caccactctg atccagtgcc cttcgcgcgg 3141541 aggcatagat acgctttggg cctgccaagc aatatcaatt acttttttca ccgggtggta 3141601 atctgacaat ctgagatcaa agacactgcc gttataatgt ttcaaatcta ttgtaatatc 3141661 aatatacatt taggatcacc cttacataga aagagcgccg tcttcttttg aatcaggcgc 3141721 tccttccctt tcatactgtt atccgcggat ttgatttgcg atgtcttggt cagtagactc 3141781 aagtgtattt gctgtttgat caagctgctg attcacatct tgaagcaaat ctgacatttt 3141841 gataaatgaa ggtttgagct gctcgtattg atctgcgaac gcttcgcttg aagcaccttc 3141901 ccacatgctt ttcaaatcag agatcattcg gtttaaacga tcaacctgat ttaatacttc 3141961 ttggctttca acgccgtatt gcttcgccat cgctcttagc tcttcgggtg tgacacgaat 3142021 taatcctgcc atattcctca ttacctcctg tgccatcagc ctaaatatgg gctaattcac 3142081 ttatttttag aacgtcatta ttataaaaac agtttttcgg catagtcaaa caaatatgtt 3142141 ttaattttac aaaatgagtc caatggttta ccccgaatca ctcaaaaatg acatatactg 3142201 taaagtaaat aggtttattt tcttaatctt ctcttcattc tccgaataat ccaaaagacc 3142261 caaataactc tccaactccc aaaaaaaacc tttcagaaaa tttgatgcta cagcaccatt 3142321 tctgaaaggt tcagtttttt ctttccttaa ttagtcttgc ctccgatgac tttcttagaa 3142381 gattaatagg ataagctgtc gtattatatg agacatacac tgtcctgcaa aaaggcgatt 3142441 acaccgccaa atgtatatag aacgtttctc tcatgaaatt gtttttttgc ttctgttctt 3142501 tgttgttgat tttcacaaac aacaacaatc ataataaaag gaaggggatg agatgtcaaa 3142561 gagaaatcaa gcacgaaaag tagggagatt tatgaccatg ccgaatgatc cgtttaaata 3142621 tagttttgac agacttgaag atgtggctga tcatatcagc gacgttctgc ggtgcccgat 3142681 caccatagag gatgttaacc acaagctgct tgcctacagt acacacagcg actgcacaga 3142741 ccctgcccgg acgtctacca ttattggcag aagggtaccg gagaaggtga ttaacaagct 3142801 gtggaaagac gggacaattc ctgctctctt aaaaacggac cagccgatca gagtcaagca 3142861 aatcgatgaa gtcgggctga gcaatcgcgt cgctatttcg atttggaaaa acaagcaagt 3142921 acttggcttc atatgggcgc ttgagatcca aaaaacattg tccgatgaag atctgctgac 3142981 attgcaaatg gcagcaaaag cagtgaaaaa caagcttctc aaacttcaaa tcagaaaaac 3143041 gaaaaatgaa gaacgcagcc aagaattttt ctggaaaatg ctgaccggac acatccatca 3143101 ggaggatgat atggcggatg ggttccataa gcttggaatg gccgctcctt cagagttttc 3143161 cgttatgatc atccgcataa atggcgagct gactgaaaaa atcgaacagc agctgcaata 3143221 tttacaggaa acgacccagc aggtttacgt gctgctggcg accgtagatt ccaatgaact 3143281 tattatatta acctcaccca aaacagatca tccttttcaa gatttaaaac agtttgcttt 3143341 aagtacgcaa aaacagctga aggagcggta taaaatagaa gacgtttcta tcgcttttgg 3143401 cggaatatac aactctattt cttttgtctc ccgctcctat caggaagcat tgtccgtctt 3143461 aaaaacgaag gaacggttcg ctgaagagac caaacatctt ttcagctttt ctgagttagg 3143521 catttatcaa tacttagatg tcttaaatga aaaacggaaa caggcgggcc attataatta 3143581 ctcgctttcc aaactggaac aatatgaccg ggatcaccag tcaaatatgg tagagacgct 3143641 agagcgcttt attgaagcgg acagcaacgt gaataccgct tccaagctgt taaatataca 3143701 cgttaatacg ttgaattacc gactcaagcg gatcagccag atcgctgaaa ttgatttgaa 3143761 aaatgtgaat caaaaattca ccatctattt agatatcaaa cttcggcaca tggatttgtg 3143821 aaatttcaca aatccatgtt tttttatttt cttaatcaaa caaagaattt tccaaaatat 3143881 caagctacac taaaaatatc acatatacag gaggagacag atatgatcat aggggttcct 3143941 aaagagataa aaaacaatga aaaccgtgtc gcattaacac ccgggggcgt ttctcagctc 3144001 atttcaaacg gccaccgggt gctggttgaa acaggcgcgg gccttggaag cggatttgaa 3144061 aatgaagcct atgagtcagc aggagcggaa atcattgctg atccgaagca ggtctgggac 3144121 gccgaaatgg tcatgaaagt aaaagaaccg ctgccggaag aatatgttta ttttcgcaaa 3144181 ggacttgtgc tgtttacgta ccttcattta gcagctgagc ctgagcttgc acaggccttg 3144241 aaggataaag gagtaactgc catcgcatat gaaacggtca gtgaaggccg gacattgcct 3144301 cttctgacgc caatgtcaga ggttgcgggc agaatggcag cgcaaatcgg cgctcaattc 3144361 ttagaaaagc ctaaaggcgg aaaaggcatt ctgcttgccg gggtgcctgg cgtttcccgc 3144421 ggaaaagtaa caattatcgg aggaggcgtt gtcgggacaa acgcggcgaa aatggctgtc 3144481 ggcctcggtg cagatgtgac gatcattgac ttaaacgcag accgcttgcg ccagcttgat 3144541 gacatcttcg gccatcagat taaaacgtta atttctaatc cggtcaatat tgctgatgct 3144601 gtggcggaag cggatctcct catttgcgcg gtattaattc cgggtgctaa agctccgact 3144661 cttgtcactg aggaaatggt aaaacaaatg aaacccggtt cagttattgt tgatgtagcg 3144721 atcgaccaag gcggcatcgt cgaaactgtc gaccatatca caacacatga tcagccaaca 3144781 tatgaaaaac acggggttgt gcattatgct gtagcgaaca tgccaggcgc agtccctcgt 3144841 acatcaacaa tcgccctgac taacgttact gttccatacg cgctgcaaat cgcgaacaaa 3144901 ggggcagtaa aagcgctcgc agacaatacg gcactgagag cgggtttaaa caccgcaaac 3144961 ggacacgtga cctatgaagc tgtagcaaga gatctaggct atgagtatgt tcctgccgag 3145021 aaagctttac aggatgaatc atctgtggcg ggtgcttaat tcacaataag cttgcagaaa 3145081 gatttctgca ggctttttta ttttttaaaa ggaaaaaaga gaccatttca cgaattatga 3145141 ctatgaagtt gatcataaag gaggattcat atggctgttc agcaatatgg cgtgttaaaa 3145201 ggcatagtat tagacatgaa gcgggaaaca gatgatgaca gtcctcattt ccaagtcaaa 3145261 atgctcggtg aagagaatac gtattacagg tgcgccatca atgtgatgtc cagttctgag 3145321 gaatctgaag tattgtattt ggctgacgat cagtttgatt cgggctcaat taccatcctt 3145381 ccgaacatgc cgtatggata tacaaggatc aatgaagcaa accgtgaagt ggcactggat 3145441 tatgtgcggg gcaatttgtt tgacccgcgg gaaatgaagc ctttgcctca tgaaatcacg 3145501 ggacctgata atgatttaaa tgattttatt gaaacctata tgaagaaagc acaagatgag 3145561 aaaacgccgg tttatatatt cggttcaaaa ttcggccctg aacaggctgc agataaaata 3145621 ttcggcttta ccccgactaa cggaatgcac aatatccata tgaatcaagg gaatgcaatg 3145681 gatacccgct ggaaaaaaga caacggctct tggcatgacg ggggtattct gattcagttt 3145741 gcagatcagt gggccgctgt gtttttagcg tttttatccc aatcttggtg taccgatgaa 3145801 aacggaaacc ctgtcagaga ttgtgatcat acccaaacgt ctgcgtaaga tagaaaaaga 3145861 gactgcggca agcagtctct ttttgataag attacacatt ttcaacagtc tttaggctgt 3145921 ttggcctcat atcgctccaa tgcgattgga tatagtccaa acaagcttca cgcccttttt 3145981 gctcatgaac gactgtccag ccgctcggca catctataaa acccggccat agggaatatt 3146041 ggccttcttc attgaccagc accaaatatg tgccatccgc attttcaaaa ggatttgcca 3146101 ttctatttct cctcccttat ttattcaact cttccaattt gacagcgaga accttgccga 3146161 tttgagccag aggttcaggc tgacataaat ctttatgacg gcagtcgatg tcgatttgtt 3146221 caatctgtcc gttaatataa ggcttccacg agtcaggttc aatcgggtca aaccattcag 3146281 gaatgattgt tgatctgaaa aacaaaacat ttccgcggaa ggttttcggc ttataggaac 3146341 ctaaaatgcc gacagaattt acatacgtat tcttcaaatt taaaatgacc gtttcatcca 3146401 ggctcgcaag cgcactgccg tcacggcgaa gaatctcaat cgccgcttca aaatctagcg 3146461 gtttttcccc taagctgtct ggatcatacc cgcctaacgc cagaagggca ataagcgctt 3146521 cctcatcatc cggtgcctct tttataggaa ggaagtggtt cggataggcg tccagcatca 3146581 ccaacaggga tacttcttct ccttgatttt gcagctgggt agccatcgct tgaacgacat 3146641 tcccgcccag ggaccagccc agcagatggt acgggccttt tggctggacc gttcggattt 3146701 gtttaatgta atcggcagcc atgtcatcaa gtgttttcgg aagctcctcg cgctgcccga 3146761 ttccccgtgc ctgcaagccg tagatcggat aatctgttcc tatattggtc atcaaaccgg 3146821 cataacacca gctgagcccc cctgccggat gaacacagaa taaaggaggc ttgtctccgc 3146881 ttgttcggag cggcagcaga acgtcaagag cgctttggct tgatcccatt tcaagtcttt 3146941 cagcgagccc ggctacagta ggtgcttcga acaagttgcc gatgctgagt tcaacgccga 3147001 gcgcttcacg aatgcggctc atgagctgta cagcaagcaa ggaatgtccg cctaaatcaa 3147061 agaaacggtc atcaatgccg acacgcggca agtgaagcac ctccataaag aggtcacaga 3147121 gaatttcttc ctgcggcgtt ctcggtcctc gtcctgtcac tgccgctgcg aaatccggag 3147181 cgggcagcgc tttacgatca agctttccat tcggtgtcag cggcaattct ttcatcgtca 3147241 caaaggcagc aggcaccatg taatccggca gtctctcagc agcatatctg cgcagttccg 3147301 ccgtatcaaa tgtttcttcc gaagggatga cataagctgc taaccgttta tctcccggct 3147361 gatcctcacg aacgatcact gccgcatctt caagctgcgg atgctgaaca agcgcggctt 3147421 caatttctcc caattcaatc cggaatcccc gaattttcac ttgatggtct gcacggccga 3147481 catagtcgag agaaccgtca gcgcggaggc gggccacatc cccagtgcgg tacatccggg 3147541 tgcctggagg accgaacgga tcagctatga agcgttcaga tgttaaacca ggccggccta 3147601 gataacctcg tgctaacccc gctcctgata catacagctc tccggcaaca cccggcggga 3147661 ccggctgcag gcgttcatcc agcacgtata caccaagatc gggaatgccg cagccgatca 3147721 agctgtttgc ccgtaaagct gccatgcttc ggtctaattc gatatagctc acatgcaccg 3147781 tcgtttctgt aataccatac atattgataa gctgcggtct attttcaggg tggcggttgt 3147841 accaatcctc taaacggctg agttcaagcg cttctccgcc aaaaatgaca tagcgcagac 3147901 tgagtgcctg tccgagatcc ggctgttccc gttccgcctg cataaactga tagaaagcag 3147961 acggtgtctg gttcagaaca gtcaccccct ctttgacaag caggcgcaga aacgcttctg 3148021 gcgatctgct gacgtggtga ggcacgatta caagacgtcc gccatgcagc agaggacccc 3148081 agatctccca caccgaaaaa tcaaacgcat aggaatggaa catggtccag atatcacctg 3148141 agctgaaacg gaaccagtgc tcggtcgctg caaataaacg tgttacattt tggtgaggaa 3148201 tcatcacacc ttttggaaca cctgttgagc cggatgtata aatgacatat gccgtattca 3148261 aaggggaaag cggctgagtc ctatccttat tttttggatt acctgcaggg tacgtgttta 3148321 gtttctctgc cagctcggga tcatccagca cgattttcgg cacgttttca actggcggaa 3148381 tgtgatttgc agctttagtg ttcgtcatga taaacgcagg ctgtgcatct tttagcataa 3148441 aagcaattcg atcagccgga taatccggat caagagggag ataagctgcc ccggccttta 3148501 gcaccgccaa taggccgaca gccatttcca acgatcgggg cagtgccaat gccacaaatt 3148561 gctccggccc gacaccttca ctaatcatca ttcgggcaag ccggtttgct ctttcattca 3148621 gctctgcata gctcagttcc tgattttcat atacaacggc aatggcatca ggacgtaaag 3148681 cagcctgctt ctcaaattgc tctggcaaac atgcgtgcgg aatcttttca gatacacttt 3148741 gccaatcagt caccatgctg ctgtgttcct ctggcgcaag aatatccaga tttccgattt 3148801 gctcgtcagg atcagactcg gcagcctcca acaggcgcat caatcggtca gcaagagcct 3148861 gagcagtttc ccgtttgaaa agatcagtgc tgtattcaag cagtccttcc attccgtttg 3148921 gtgtcccgtc agcaaggcga tcttcactaa tttccagcgt caaatcaaac ttggcagaac 3148981 cgacactgtt gattcgcagg ctgctctcca tatcaggaag atgcagttca gcgtccggtg 3149041 tgttttggaa cgcaagcatg atttggaata aaggatgcgt cgcacgcgaa cgagccggat 3149101 tgagcacctc tacaagtctc tcaaacggca gatcctgatt gtcataggcg gccagattca 3149161 cttcccgtac tctgtctaga agctcacgaa agcttgggtc accggacgta tcagttctga 3149221 gcaccaatgt attaatgaac agccctacaa gatcgcccag cgcatcatca ttccgtcccg 3149281 cgatcggact gccgatcgga atgtcggtgc ccgccccgag ccttgtcaat aaagcggcga 3149341 gaccggattg aagcaccata aacaggctca ccctatttgc gcgagccagc tcctgcaatc 3149401 gcttgtgaaa ctcgggctca atacgaaaat gaatcgtatc tccatcatga ctcggctcag 3149461 ccggacgtga ataatcggtt ggcagttcaa gctgatcagg caggtttttc aaggtttctt 3149521 tccagaaagc aagctgtccg gcaatcaagc tatttggatc atcctcgttt ccaagcagtt 3149581 cttgctgcca aagcgcatag tctgcatact gcacagcaag aggcgcccat tcgggagatc 3149641 gtccgtggca gcgagccgca taagctgtcc caaggtctct ggtcagcggt gttaaggacc 3149701 agccgtcccc gacaatatga tggacgagaa gaagcagcac gtactcgtca ggaccgatca 3149761 caaaaagctc ggcacgaaaa gcaggttcag ctgcaagatc aaagctgtag cgtacagctt 3149821 cggcaagccg atcagaaagc tccttctcag caatttcagt aacatgtaac tcgggacagg 3149881 ctcgatcggc atctaaaata tgctgatagg atgtcccctg tgattcaggg aagatcgtcc 3149941 gaagactttc atgacggcag acgaggtcat aaagtgccgc tttcagcaat ccttgatcca 3150001 actcacctga caaacggaca gcaaccggaa tattataagt aggactcggt ccttccagac 3150061 aatgcaggaa ccatagccgg cgctgggcaa atgagagcgg gatcttttca ggccgctcag 3150121 ctctctgcaa agcgggacat gcactctgcg ccaaatcaag atgggcagcg agtccggcta 3150181 ctgtcggttc gtcaaagagc ttggcgatac caagttcggc tcccattacc tcgcgaatgc 3150241 ggctcatcag acgggctgca agaagagaat ggcccccaag ctcgaagaaa ctgtcatcga 3150301 taccgacgcg tgccaaaccg agaacctctg caaacaagtc acacaatatc tcttcctgag 3150361 gagtccgcgg ggcccgatca ctgacagatg tgctgaagtc tggtgccggc agtgctttcc 3150421 ggtcaagctt gccattaggt gttaacggca gctcgtccat ctccacaaac gccgacggta 3150481 ccatataatc aggaagacta gcccccatat aacgacgaag ctctgcagta tcaatagcag 3150541 catcagcgac tacataagcc gccaatcgtt tgtctcccgg ctgatcttcc cgtacgacaa 3150601 ccgcggcctg ttcaatgtgc gggtgattgg caagcacggc atcaatttct ccaagttcaa 3150661 ttcggaatcc gcgaattttg atttgatgat ccgcccgccc gatataatcc aaagacccat 3150721 cggcgcgcca gcgggcctgg tctccggtcc gatacatccg agttcccggc ggtccgtatg 3150781 gatctgcaac gaagcgctcc gccgttaaat caggacgatg gaaataacct ctggccaagc 3150841 cggttcctgc aatataaagc tctccgacaa cgcccggcgg caccggctgc aatccattat 3150901 caagcacata cacctgcgtg ttccaaatcg gtttcccaat cggaggaacg cccttcagcc 3150961 cttcttcaag aaaagctgcg gcagaccaaa tcgttgtttc agtgggaccg tataagttcg 3151021 tgactgaaca atgaaggtct tgaagttcct gcaaaagacc gctcggcagc gcctcgcctc 3151081 ctacaagcac tctaagcccc cgaagtttct caggttcact cgttaccaaa gcgtgccaca 3151141 gtgtcggtgt cgcctgcata atgttaatat cgaaattttc aatcatttga gctaatgcct 3151201 gcggctcacg gatcgtttct ttctttgcga tcacgatttg cgctccgcta atcagcggaa 3151261 gatataactc caatgctgaa atatcaaaag cgacagtcgt cacagccaac agcctgtctt 3151321 cttctcctag agaaaatgcc tcctgcatag acagcagaaa attgcttaag cttttctgtg 3151381 tcacaacgac tcccttcggt cttcctgttg atcctgaggt atagatgata tacgcaggat 3151441 ggtcaagcga aaccgataca tcctgatttt ccggcgaata gcgttttata atctcctgtg 3151501 taacagcctg atcaagcaca agctcaggta cagccaggtc atcaggcaga ctggctgcta 3151561 tttcctcagt cgttatgatg catgaaggtt tcgcatcctc cagcatgtaa gaaatgcggt 3151621 cggctggaaa ctccggatca agggggagat acgccgcacc agtcttgagc acaccaagca 3151681 ttgaagccac catctcaggg gaacgcggca gcgccaaagc gacaaattgc tccggaccaa 3151741 tccctttttc gatcaacaga cgcgcgaggc ggtttgcctc ttcattgagc tttcgatagt 3151801 tgacttgaat gtcatcacac atgagagcga tacgttctgg cgtaagaact gcctgctttt 3151861 cgaacatgtc ctgaaggctg accagcttct cggattttgc cgtctcattc catttagaaa 3151921 tgactttttc tttctcctct ggcaacagaa gctccatttg cccaatcagc atgtcctctc 3151981 cggcagaagc cgtttgcagc agctgcaaaa tacgctgctg atgaagctta atatcagact 3152041 cactgtatac ctcgggattc gcatcaacat caattcgcag cccgctgccg tctgttctgt 3152101 catatacatt gattgataga tcatcaacag gaccggctga aagattatgc gttgtgcccc 3152161 ggacgccggc aaagtcgaga ccgtaatcaa acggcataag attgatttga gggccaaata 3152221 atctatgatt ttctcctatc aatttcagat cgcgcctaag ctcttcatgg cgatacttat 3152281 gatgtcgccg aatactgcgg atttcccggg aaatttgctg aatcagttca gaaaagctca 3152341 tcgaagagct taccgtcagc cggagcggga gaaggttcat caccatagcc ggtacattca 3152401 gtgacgcgga ccctatccga cccatcatgg gcaggccgag cacaacatcc tcagagccgg 3152461 tcatacggtg cacataaaca gctgacaccg caatcatgac ttcatgccag cttcctgaga 3152521 aatagcgcgc cgcttctttt aacgcgttta catcagacgg aggcagatat gccgtatgac 3152581 gaagaaaact gttagatgtt cttggcgccc gatcagccaa gctcacaact tcaggtgcat 3152641 ctgcaaaacg gtccagccag aattgacgat ccttctcata ctgctctgat ccgcgataat 3152701 ctgtatcctc ctccaaaatg gcctggagag acccaaagga acggctttta gctgtttgtc 3152761 cttttataag ggcagtatat gtacttgcca cacgctgggc tatcagggaa aaaccgaagc 3152821 cgtcgatcgc tatatggtga atgcgctgat accaaaagaa acgatcaggc ccggcaataa 3152881 acagagcttc attgaacaaa ggggcatacc ctaaatcaac cggctttgct aaatcagctt 3152941 tcatccagtt taatgctgtt ttttccggat caggctcaga gctgacgtca atgacgtgca 3153001 gctgtacatc cggagacggg tttatcatct gccaaggccc gtccatattt tcaccgaagc 3153061 ggacatgcag cgattccgct tccttgatca cgtgccgcaa agcttcttca aaaagagcaa 3153121 tattgactgg tccattgatt tctatatatt ccgctgtatt gtagattgga ttgtccggat 3153181 caagctgctg agcaaaccat atgccagttt gcgccccggt caaagaatat tgaagatctt 3153241 ttgtatcagg catccgtttg tttaccctcc ttttataaat aatccgcgtt tggcagcact 3153301 tgctggctgc gagttgtgag caatttctgc cattcttcga tcgttgggcg ttcagccaat 3153361 tccacgaaag tcacctctgc cccttcacgg cgccattgtt ccaccaatgt catgatcctt 3153421 accgaatcaa gaccacgatc gagcaaatcc tcttgatctg tgatgtcttc cggtgtttct 3153481 tgtagaagct cagcaatttg tttacggata ttctcacatg taaacacgtt ctttttgcca 3153541 gtgtttgctg acgttttttg aacgtctgcc ggcgcattct gcagctgatc aagaagactg 3153601 tcagtcatca cggtaaacgc acagcgtcca gccgcatatt ccagcgccat ttgatgtttt 3153661 tctaatgaaa aatcagcaac tgcatctccc acaaaaaagg ctttaatatc ctccataaat 3153721 gcttcacatg ctgtaacaag acagccgata tgggcgtaaa ttcctgtaat gatcagctga 3153781 tcgcgtccct ctttgcgcat catttcaagc agattcgttc tcttaaacgc gctgtatctc 3153841 cattttgtca gcacaagatc atcatcctct ggtgccagct cggttataat tttctcctca 3153901 taaggaccgc tgtttaatcc cgggccccaa aagtctgtca gcagcgcacg gtcatccgga 3153961 ttttggcttc ccggctgtgc ggtatagaca acaggaatcc caagctgaac acattgattc 3154021 ttcagctttc gtatattcgc tgaaagctct gttaccggag acgctcccgc tgtgaaagca 3154081 tcaacaaaat agttttgcat atcgtgtatt aacaagacag cccgattcgg atcaggcacc 3154141 catgatactt tgttttgcgg catatcagat gctgtcggca tttgatacgg ctgaatggca 3154201 ggtatagcca tatgaacact tcctctcaaa ttgttgtttt attttttaaa tcctgcaaga 3154261 agcttctcgg aaatggcttc acggagcgct tttttgctga cttttcctac tcctgtctgc 3154321 gggaaggatt cgacaaattc aactcgatca gggattttat atgccgccag tccgcgctct 3154381 ctcaaaaatg ctttaagctc tgcggctttt ggggcttcat cccggggaat aatgaacaca 3154441 caagatcttt cgccaagaaa ttgatcaggc atggagacca ttgccgcatc atggacagcc 3154501 ggatgcgcca gcagatgatt ttctacctct tcagccgcaa ccttttctcc tccacggtta 3154561 atttgatcct tcgcccggcc ttcaacgaca atatagccgt ctcgtgtcag cctgacgata 3154621 tcacccgtac ggtaaaaacc gtcctcagta aatgaagcgg cgttatgctc ttctgcctta 3154681 tagtaacctc gaattgtata cggcccccgc gtcagcagat ggcctgtttc accaggtttt 3154741 acgtcgcgat catgatcatc ccaaacacgc atttcatcat atggagacat cggttttcct 3154801 tgggtgttga caatgatctc ctcaggatca tccaatctcg tataattgac gagaccctct 3154861 gccattccga acacctgctg cagcgtgcag ccgaaaacag cttttaccct gcgcgcggct 3154921 tcagcactaa acttggcacc gccgacctgc agcacttgaa ggctggataa atcatcacgg 3154981 cgtgaggatg ccgcatccat ccataccatc gcaagaggcg gaacaagagc ggttatcgtg 3155041 accttttccc gttcaattaa aggaaatgcg tcatctggac ttggagaagg agataatacc 3155101 actcttcctc cagcgtataa tacgccgaga acgccgggtg agctcagcgg ataattgtgt 3155161 gccatcggca gcgcggccaa gtacaccgtg ctgtggtcga gccagcagac ctccacactc 3155221 cgcttcaggc tgtatatgta gtcatcgtgg gtcctcggaa tcagtttcga tagcccggtg 3155281 ctcccgccag aaagctggag gaacgccaca tccgatgatt tgacttcagg cagttttaca 3155341 ggttctgcat gcaaatcctc cagcggtaaa aattcctctg cctcacctgc gacaatgatg 3155401 tttttcaaag tcggcagctt gctttgaacc tgtctggcaa gcgaacggta gtcaaaaccg 3155461 gaataagcgt cgggaatgat atatgcagcc gcttcagcaa actcgcaaaa atatgtaatt 3155521 tcactgcttc gatgagaagg cagtgcgaag actggaagcg cccccagacg gaaaagcgcg 3155581 aaaatgactt caaaaaactc tttgatattt ggcaactgca ccacaacacg atccatctgt 3155641 tgaatgccga gcttttgaaa tccggcagcc aggcgatcag cccttgtgtc aagctctcga 3155701 tagctccaat gggtgtttcc gcatgtaatg gcaatgcgat caccatattt ggctgcccgg 3155761 tcccttaaca aatctccaaa cgtctcaccg gcccagcagc cgttctttcg ataggtctca 3155821 gctaactcat caggccaagg cgtaaatcct ttcagcatgt tgtatccctc cagcaattca 3155881 ttctgttcat atgtgatcca cgcccattgc ccgcagcatt gtccgaaact ttgcggacgt 3155941 ctcctgaagc tcgtcctcag gctttgaacc ggccacaaca ccagctccag catacaggcg 3156001 gagtgagcgt tcttctgctt ctgcacaacg gatggtcacg atccattctc cgtcaccggc 3156061 atcgtcacac catccgacca tgccggtaaa gaaaccgcgg tcaaatggtt caatgctgag 3156121 aatcgcttct cttgcaagat cagtcggtgt tccgcagacg gctggcgtcg ggtggagcgc 3156181 cgccgccaat tcaagtgcgg ttacagacgg gtcggaaagc tctcccttaa tcacgctgga 3156241 caggtgccac atcgtttccg ttttgatcag tgaaggcttc tccggaacct ccagcgtccg 3156301 gcagaaaggt ctcagcgctg ccgcaaccgc gtcagcgaca accgcgtgct catgaagatc 3156361 ctttgcggaa gaaagcaatt cagctgcccg gcgctggtct tcaacaggat cattactgcg 3156421 cggtcttgag ccggctaatg ggttggaaac gacctgtgtt cccatccttg aaacgagaag 3156481 ctccggactt gctccgagca atgttctgcg gggagacgtt tcctcctgac tggacacgtc 3156541 tgcggcaaac gtgtagccat gcgagttatg ctgagccaga tggcgaagca attcatccgt 3156601 ctgaatcggt tcaggcgatg tcaaatgcag cgatctggac aggacgattt tgctgagtgt 3156661 tccatcggca atgcgtgcca gcccttgttc aacaccattt ttataatcct caggttcagg 3156721 aacaggcttt atgtggtatg tatgcccagc ctgctgttcc ttttcctcat gatcaaattg 3156781 aagcggtcct gaccagcgca cttcttcagg tacaacgagc cgcgctgctt ttacttgatc 3156841 aaaaggaacg gccccgacaa caagcggccg gctttgccct gattgttttg cctgacgtaa 3156901 cgcctctgca attcggccag aaagggtttc catttggttt tgcccgtctg cctccggtac 3156961 aatttcacat atgcctttcg ctaacagtac acgatgagga gacgctaaga aaaaggcgcc 3157021 cggctgatat tcatgaagca aatgctccgc ttttgtttct gttataacgt tttgatccaa 3157081 cattctcatg aacctccttt aaattcagtt acacgcctaa ggtcgcgccg ccatctacgc 3157141 ataaattatg catcgtaata tgccctgcct ggccagaaac caaaaagagc accgcatccg 3157201 caatatccga aggcttggct agttttttga gcgggatccc tgttttaaat gtctcaagtg 3157261 atccttttat gacttgctcc gctccattct cgtcggccca taatgaccac tgcatgtctg 3157321 tttccgttga tccgggagat acaatgttgc agcgaatatt gtattctgca agctcaaggc 3157381 caaggcattt cgtaaacatc acagccgcag cctttgaaga cgcatatgcc gccatagatg 3157441 ttcttggtac accggcagca ttcgatccga ctgttacaat cgaacccgat cttcggtcca 3157501 tcatatattt gctgactgaa cgcgaggcgt taaatacgcc agtcgaattc actgagaacg 3157561 tcgcctccca ttcctcatcg ctaagcgaat ggatcagtcc cgggcgaagg acacccgcta 3157621 cattcactaa aatatcaatc ggccccattt cacgttcgat gcgcgccgtg atctcgtcaa 3157681 tcgccgcgct gtctctcaca tccgcaggaa aagcttctgc atggcggcct tctgctttga 3157741 ggctgctcac aaccttttcc agcttttcag gattataatc aactgccgca atatgtgcgc 3157801 cttgactggc aagcgtccgc gcaacagctt cgcctattcc ttgggcagcc cctgttataa 3157861 aagcaatttt tccctctata ccctttgcat tcatatcatc aattcctttc ttcgctctaa 3157921 atgccaaaca gacatccagc gaaaaagact gctgcgcctt gaaaaacgca atctattgat 3157981 aatgattatc attatcaatt ataaaaataa tcatatccaa atgtcatgtg acagtcaaat 3158041 ataatttcag tgacaaatat ttttttaaag gcaaggctga gtatgtctca gcccattgat 3158101 agatgcggtc cgtcagggtg aagcgcaaaa cgcagcgccc tgctgaccaa aacaggaaga 3158161 actgaaatat gtccttctcc tgaaaactcg caaaattctg cccgtatacc ttgttcagat 3158221 aaaacggcca gccgctcata aagctccctt gcattatcat tcatccggct tttatgatgc 3158281 tgctctaatt ctcctgcggc aagcaggata ttgataggct gattgttttt cttggtgaga 3158341 gagacgaaat ggtccgtttt cttgagaata aacggtttat tccaatgaat ggacggactt 3158401 cccgcgatat acgtttgaaa cgcatcgggc tttgttagca gcacctgcag cacgaaaagc 3158461 cctccgagcg aatggccaaa gattgtttgt ctttttttat caatctggta atctcgttct 3158521 atctccggtt ttaaatcctc ttcaataaat ctgaaaaagc cctccgctcc gccatgctcc 3158581 ggccattctc tgccgtcggg cctttccggc agcttcgatt gggctgttgg cattgtaaaa 3158641 tcccggtggc gtgctgagga gaacggctcc gctgtctcat agccaatgcc gacgatcact 3158701 gcagggatca ccccggtttt ttcgggtcgg cgtccctgta ttcgaacggc ttccgtcatc 3158761 gttccgaaga cagaattggc atccagcaga taaatcacag gataaccagc gggtggcggc 3158821 ggcgtactag gtttcgagat aaaaatgtga taggtacggt tttcattgcg tgaagacatc 3158881 atacgcactt ccgtaccagg aatcgtaaat gcgtttgatg tcccgccatt tgtccggtct 3158941 gttgtttgtt ctttcatgca gtacgacatt cctctcctta aactaaaccg caatgtatga 3159001 taatgatttt cactatcaac tagacacctc aaataatagg ttttcttcca aagaaagtca 3159061 actttttccc gaataaaaaa ggcaccttga tcaaataagg tacctgcaga ctatcaatat 3159121 ggaagtaaaa acctaataaa gatgcgtatt gtcctatttg aaatagaacc ttaatcccat 3159181 gtaaaccttt gattttgcca agggtcgcct ctcatgtgat agccattccg ctcccaaaag 3159241 ccagggtgat tttctttcgt aaattggatg ccgcgcagcc acttggcgct tttccaaaaa 3159301 tacagatgcg gaaatacacc ccgcagcgga aagccgtgtt caggggttaa aggttcgcca 3159361 ttatgcgcat aagccagaag ggaagtttcc gctaagaaat catcaagcgg cagattggtc 3159421 gtccagccct cttcagcatg taaaatgacg tagcccgctt cttcttttac acccgctttt 3159481 tccgctatat cacaagcccg cacgccttgc cacacattat caagccttga ccatcccgtg 3159541 acgcaatgaa tgtcgttttt cgattcatac cgtggaaagg ctttgacatc ttcaaagctt 3159601 agcagcatcg gatggtcaac caaaccgtat acttgaagat tccatttcgt catatcttcg 3159661 taatatggga catctccggt atgaagcaca ggaaatgaag tggtgacgtt ttgatttggc 3159721 ggcactcttc cagattgatc ggactgtctt gtttttccga aatacatatg ggcctccttt 3159781 ttgttaacct aatttaaaat catgttgaca atctttttgt tctttattac tctatgattg 3159841 tgtatgtcaa cctaaggggg aacaacgatg aaacaacgta aacttcgtgc gggagatatg 3159901 gcgctgattg gcatgttcgc cgcacttatg gctgtcgggg ccaacattac atcagtagca 3159961 ccctttttac aagtagccgg cattccgctt tcgatgcagc cgtttttctg tctcttggca 3160021 gctttgcttc ttggcagcaa acgggcagcg attgccatga ttgtatatgc acttgtggga 3160081 ttggccggag cgcctgtgtt tgctcaattt tcagcaggct tcgcaccgtt tgcagggaaa 3160141 agcggcgggt ttattatctc atacattccg gcagcatttg cagcgggatg gtttttagaa 3160201 cgaaacattc agccaagtaa aattcgattt ctcattgctt cacttatcgg aacggcgatc 3160261 atgtatctca tcggcactac ctatatgtat cttgcactga agctgtggat tcatacgcca 3160321 gtgagctacg gcacggcttg gggctttatg atttggttta tggtaaaaga tacagcgctg 3160381 gctgtgatac tgtcgtttat cgcaccagca atctaccgct ctattcataa agcaaccggc 3160441 tttaacagaa atcacatatc atctacgtaa aaaccgttct attggacggt ttttttatca 3160501 taacgagaaa aggctcccca gtaaagggga gcctttttcc tataaaacaa gcgctgcaat 3160561 ccagccaaag atgacaagcg gaatattata aaatataaat gtcggcacac aagtatccca 3160621 aatgtggtga tgctggccgt ccgcactcaa acctgaagtc ggcccaagcg tactgtcact 3160681 ggcaggtgaa ccggcatcgc caagcgcagc agcagccccg ataatcgcaa tcgttgccat 3160741 cgggctgaat ccaagctgca tgcatagagg cacgaaaatg gttgtgataa caggaatggt 3160801 cgcaaaagaa gatccgatcc ccattgtaat taataagccg acaatgagca tcagcaatgc 3160861 gcccaaggac tgactgtgtc cgataaaacc agctgacgtt ttgaccagtg actcgacatc 3160921 tccggttttc gtcaatacgt ttgaaaatcc ggctgcaaca agcatgacaa agccgataaa 3160981 ggccattaaa accattccat cagtaatcag tgagtccgct tcatcacgct tcatcacacc 3161041 gctgacaaac agaacaatca gaccagcgag cgcccccata atcattcctt ctactcccaa 3161101 agtctgagat aagtaaagct ggacgccgag tgacacaaca atggctagaa ccgcgatacc 3161161 aatacttttt ctcgtatatg gcgatgcttc tgcacctgaa atgtcttttg tttcatattg 3161221 tttcggttta cggtatacga tcactgataa aataaggccg acaaccatac ctgcaactgg 3161281 aataatcagt gcgtacggaa tatcagcaag cggaacgttt aacccggcat ccgccatatt 3161341 gtccttcagc atgccttgga agatttggcc gaaaccgacc ggaagcaaaa tataaggagc 3161401 cgttaagcca aatgtaatta cacacgcgat cagacggcgg tccatttcaa gttcattaaa 3161461 gattttcaaa agcggcggaa tcagcaccgg gataaacgcg atgtgaaccg gaacgacgtt 3161521 ttgcgaaaaa caagatacaa ttaaaataat cagcacaatc agcaccttag acagtgcttt 3161581 ttttcgagaa tcttctttat ttccgattaa tttaacggag gcttccacca ttgcgtccgg 3161641 aagacccgtt ttcgtcaaag cggcggcaaa cgcgccaagc atggcatagc taactgcaac 3161701 ggtggcattt ccgccgagac cgtctgtgaa agctttaacc gtttcgccaa gaccgagccc 3161761 gcctgttaac ccgccggcca aggcgcctat aattaatgcg ataacaatat tgacacgcag 3161821 caggcttaat acaagcataa gcaggactgc gatgacgact gcattcatga tgatacccct 3161881 ccaaaaatcc tttagtttgc taatgtagta gataaataaa gtacgaacgt atcgtatcat 3161941 aaccgatcca ctttagtcaa ctaaagattt cggaagaaaa aatccctgcc gcatcataca 3162001 gcagggattt ttcattactc gtttttatct tcttccaatg taaatcgctc cgcaagtgta 3162061 gccagtgttc ttgccataac gccagtagcc ccggccggtc cgaagcaggt tgctttattg 3162121 gcagtcgctg tgcctgcaat atcaaggtga acccaaggtg ttgactcagc gaattcacca 3162181 agaaacgttc ctgccataat cgcatgtccc tcgcgtcccg gtgaattgct gagatccgcc 3162241 atttggctgc ttttcacgcg ttttttatcc ttctctgtta tcggcagctg ccagatcgcc 3162301 tcgccgcact cttgtgcagc atcagctacc tgctggtaaa agctttgatc atttgtcatt 3162361 gcaccggttg tttctgttcc taatgccaca acgacgccgc cggtaagcgt agctacatcg 3162421 acaagaactg atgcgccatg ctgtttcgcg tatgtaatgc catctgcaag cactagcctt 3162481 ccttcagcat ccgtattaag gatttctatt gtttttccgc ttaaagatac gatcacgtca 3162541 tccggcttca tggccccgcc ggagatcata ttatcggttg atggaataac gcacagcacg 3162601 ttttgttcag gacgaagctc tccgatcgtt tccatagccc cgagaaccgc agctgctcct 3162661 cccatatctg atttcatgcc aacaattcca gatttcgttt taatggagta gccgcctgtg 3162721 tcaaaggtaa ttcctttccc gactagtccg acgacgtctt cccattcctt tttgccctga 3162781 tatttcaaca caatcatttt cggcggttcg gtggagcctt ggtttaccgc aagtattccg 3162841 cccataccga gctcttccat ctctgatttc tccaatatct cacactcaaa atcatatttc 3162901 gccgcaagct cttcagcata cgaagcgagg tcagtcgctg tcagcatgtt tcccggcata 3162961 ttcacaagcg ttctagccga atttgtccct tgtccgtatg cctggccgac gcgaagccct 3163021 gcctgcactt cctgtgtatc ttcatctgtt acaacataca cggcttcaat ttgtttgtca 3163081 ggctcatttg atttatgctt ataatcctgc acctcatagg aagcaagcag gcagctctca 3163141 gctaaagcat gagcggcatc ggctggaggc acgtcttccg aaataaacgt atcaagcaga 3163201 acagcagttt cttgttttcg atctttatga atggcttgaa aaacatgagc aaaacgttcc 3163261 ttcgcctgtt caaacgaata atttgcttct ctccccaggc caacgaaata aatccgtttc 3163321 atacccgcag aagatggagg gaatactttt gatacttgat tcggtttcgc agagacatca 3163381 ccctctttta aaagctgtgt cagatggcct tcgagcattt catcaatttc caacgctttt 3163441 cctgtcagct ggcttttttg aaaaagcccg acaacaaggg tttctgtatg ctctgattgt 3163501 tgaaccgcat aaaacatgag gcttacactc ctaacgtaat gggtatttgt aatgaacaat 3163561 ggtataatag gaaaaacatt ctttccacta tacttatttt aacaaacaac agtctaagac 3163621 ttgctttttt cttttgaaac acgaaggatt tttcaaatag aaaggatgtc gccgatggaa 3163681 cttttaacga attttccttt attatcaagc ctggccgcaa ttatttttgc tcaggtcatc 3163741 aaagtgccca tacagtttat cgtgtccaga aaactggact ggtcgctggt cacaagcaca 3163801 ggcggcatgc ctagctctca ctccgcagcg gtcactgcgc tttctacagg cgtagccttg 3163861 gagcatggat tagactcctc actctttgcg gtttccgcca ttttcgccgt cataaccatg 3163921 tttgacgcaa ctggcgtcag acgtcacgcc ggtgagcagg caacagtcat taataagctt 3163981 gttattgatt ttaaccgttt cgtaaatgaa gcgaaggact tccctaaggc tgcagagaaa 3164041 gaaaagcaaa aaaagctgaa agagcttctc ggacatcagc cgatcgaagt ctttttcgga 3164101 ggattaacag gtattttact gacattggta ctcgcttact ttttcatgta aaaaaaacgc 3164161 tcctgctttc gctggagcgt tttattcttt caccgtttta tattgatttc tgaacacttg 3164221 caaagatttt gtttcattga gcttctcaag ctcatcctcg gtaatctttc ccgttccctt 3164281 tttaatcaca tatacatcaa gggttttttt gccccattca ttgtatacat ctttgactgt 3164341 ctcaaagtac agatcaaggc ggtttccctt aatagctgat cctgtgtcgg ccacaactcc 3164401 gagaccgtag ttcggaatga ataaaattgt tccgatcggg aaaacggacg ggtcagcagc 3164461 aaccgtggaa tataaatccc gtttcacttt cacacctgaa tatgtaagcc cgtataatgg 3164521 atcaccggga tttttgcccg tcgactcagc tcctgctgtg tagcctgttg ctgttactct 3164581 ttggactgga tattcatccc aatcaaatgc ctcttctaac ggttttgttt tatcctcagc 3164641 cgcggacgtg gtttgtgttt gtttctgctg caatgctttt aatctcagtc ctgcatgctt 3164701 caagtgcttt tcctgatgtt cctgcaccca ttttgacaag tccttcgctt caattcctga 3164761 cactgataaa aatgtcgtgc caaatgcaag cagaaataaa caggtcatca gcaaacgtct 3164821 gatcatattc aacatcattc acctctcctc cgaatcattg ttcccaagtg gagagagcat 3164881 tattcaaaat ggtgaatgag ctgaacgcat aaaaaaagct ttctttagaa gaaagcggca 3164941 tttaaaacat ttgatatcct ctttttctaa gcatgttgat cgctataccg gacacgatgg 3165001 cgccggccaa accgctgact aaaatcagca catcagcagc cgctaatgat aagacacgat 3165061 gaaacaggct ggcaaaggat tctcccggcg actggacata gctgatcagc ttttctttgc 3165121 tgataatgaa aaggcataca attggataaa tcacagccat aatccaagac attctcagca 3165181 gcatgtttaa taagaaaccg attccaaaaa acaagacaaa aaacaaaaca attgagatga 3165241 ttacgactgg cagactaatc aacctattcc acccccctgc gttgttttta gtgtaacgcg 3165301 ggggctgaaa taaagtcaac ggctggaaaa agaatgactg tcttttcctg tcccctggca 3165361 agacggacaa gtctctgaac cgccgagaat caattgaaaa tatcctttcc ctgaacaaaa 3165421 tgggcatgca tgtgaagcgg ttgtcgttgc agttttcatc taatcatcac cctttttctt 3165481 aattttctga taatatacca tatcaagctg tcaacaataa agtcagatca tgtgacaaat 3165541 cttttgatgt aagcggaaac atacttgttt tcctctcgtt ctctttttat tttggcgttt 3165601 tttaataaag aaaacccgct tccgcgggtt tttagaaaaa cttgaacttg ccttttttca 3165661 atgtcagtcc gagtccgcca atcataaaca gtgagcggtt atcaatgact tttttcataa 3165721 acgaagcggg cgtgcctttc agctttctgc cataaacaac cccaaccgcg ttatgctcgc 3165781 caagagaagc cactgttccc ttaatgtccg gcttgaattc ctcaagctct ccgcctttaa 3165841 taagcctgcc aaggttttta gcgaccgtta tgccctgctg cattgcaatt tgcgcagtcg 3165901 gcggatacgg gcgctctgta tcttcattca taaacagcga gctgtcgccg agaataaaga 3165961 cattgtcatg tcccggggcg cggagatcag ggttgacttt gactcggccg cgcatattct 3166021 caaaaccggc ttcctccaca atcggatggc cgcggacacc tgccgcccat acaacggttt 3166081 gcgatttgat ctgctctggt tcttcatctt ttttgccgac tctgactcct tctggtgtac 3166141 attcttgtac agccgttccg atcttgaact caactccgtt ttcctcaaga taatgtacgg 3166201 cgtaatcaac aagttccgga tcaaagcccg gcaaaacggt cggcgctgct tccacacaaa 3166261 tgatgcggac aaggcttctg tcaacgtcat attccttaca gagctccggc acgcgagcag 3166321 ccagttcgcc aagaaattca attcccgtaa atccggcacc gccaacaacg atcgttaacc 3166381 tgtccggccg tttttccgct tccgtattgt aagtcgcaaa ctgcagctca atatgttccc 3166441 gcagcaggcg cgacgtgttg atgttggcaa tcggaaacgc atattctttt aagcctttaa 3166501 tgccgaacgt ttcaggcacg gcgccgagcc cgatgactaa ataatcgtac tgcaattctc 3166561 cattcgcaag cacaactttt ttctcatcaa ttttgattgc ctttacggta tcctgtacaa 3166621 aattcacccg tgactggttg attacatctt ttatctgata acggcagcgg tcatgatgga 3166681 gcgtacccgc gctcgcttca tgcatccatg tcgtttcata atgataattg tgtttattta 3166741 caagcgtaat gtcagcatca ttcggcccga catacttcgt cagccttgtc accgtcatca 3166801 atccgccata tcctgcacct aaaatcacga ttttgggctt attcaatgcc atcacatcca 3166861 ccttctcttt ttttgctttt gttagaccca taataaaatc atcatttgtg ttagcttcag 3166921 cttattggcg ggattttatg aaatatattg aaaagttttt tgtgaagtcc ttacccgtag 3166981 cactattatc atgtttatcc ggctggccca agaaacattc agaaaaagat catttcattt 3167041 ggttattatc gtagcggcct gcggaaatat tttcaagaac ggatgggcac gttagatcct 3167101 tacgattttt tctgctgact cgtcaatttg aacggcaata tggtataatt aataacaatt 3167161 ttcatttagg aggcaatttt cgtatgcgag aggatacaaa ggtttatgat attacaatta 3167221 taggcggggg accggtcggc ttattcaccg ctttttacgg cgggatgaga caggcaagcg 3167281 tcaaaattat cgaaagcctg cctcagctcg gcggacagct tagcgcccta taccctgaga 3167341 agtatatata tgatgtagcg ggattcccga aaatccgcgc gcaagagctt atcaataacc 3167401 taaaagagca aatggcgaaa ttcgaccaaa ccatttgtct ggagcaagcg gttgaatctg 3167461 ttgagaaaca agcggacggc gtgtttaagc ttgtaacaaa tgaagaaacc cactactcta 3167521 aaacggtcat cataactgca ggaaacggcg cattcaaacc gagaaagctg gaacttgaaa 3167581 atgccgagca gtatgaaggc aaaaacctcc attacttcgt tgatgatctg caaaaattcg 3167641 ccggcagacg cgttgcgatc cttggcggtg gagattccgc ggttgactgg gcgcttatgc 3167701 ttgagccaat cgcaaaagaa gtatcgatca ttcaccgccg cgacaagttc cgagcgcacg 3167761 agcacagtgt ggaaaacctt catgcgtcga aggttaatgt cctgacacca ttcgtccctg 3167821 cggagctgat cggcgaagac aaaatcgaac agctagtgct tgaagaagtg aaaggcgacc 3167881 gcaaagagat tttagaaatt gatgacttaa tcgtcaacta cggtttcgtt tcatctcttg 3167941 gaccgatcaa aaactggggc ctggacatcg agaaaaattc cattgtcgtg aaatcaacaa 3168001 tggaaacaaa tatcgaaggc ttctttgcag caggtgacat ttgtacatac gaaggaaaag 3168061 tcaacctgat tgccagcggc ttcggcgagg caccgacagc agtgaacaac gccaaggctt 3168121 acatggaccc gaaagcccgc gtacagcctc ttcactcaac aagtcttttt gaaaataaat 3168181 aataaaaaaa ggagcttgtg tctgcgacac agctcctttt ttatttgaag atatttatat 3168241 aattcaatgc agttcctaca accagcgcaa tcacaagggc tgcgactacc cagatcattg 3168301 ccataataat gcggtcctga atcttttggg acttcggtgt tttttcttcg ttttgggcca 3168361 tcttattcgc tcctttccca tgtccatgcc ataaagaaag cctggtgctg aacgaccaag 3168421 ctttgctgaa cgtatatcat tcgcgttttg atccgctctc taagaccatt cgttaaaact 3168481 atgataccta aactcaccct gcatgacaag cttcggcact tgcaccacac ctgccagcaa 3168541 atcataatgt ttgacatcct aaataaaaca gagtacatta tataaggcga acatttcata 3168601 tattatactt ttaaatattc gtttttagga gtgaaaacca tggaaaacgt atttgattac 3168661 gaagatattc agctaattcc tgcaaaatgc attgtgaata gccgttcaga atgtgataca 3168721 tccgtacgtt taggcggaca tacatttaaa ttgcccgtcg tccctgccaa tatgcagacg 3168781 attatagatg aaaaactagc gatttcatta gccgaaaatg gctactttta tgtgatgcac 3168841 cgatttgagc ctgagacacg aattgatttt attaaagata tgaacgcacg cgggttattc 3168901 tcttctatca gcgtgggcgt caaagatgag gagtatgaat ttgtccgcca gctggcagaa 3168961 gaaaatctga ctcctgaata cgtgacaatt gacattgctc acgggcactc aaatgctgtc 3169021 attgaaatga tccagcacct taaaaaacat ttgccggaca gctttgttat tgctggcaat 3169081 gtcggaacgc cggaagcggt cagagagctt gaaaatgcgg gagcggatgc cactaaagtc 3169141 ggcatcggac cgggaaaagt atgtattacg aaaatcaaaa caggcttcgg cacaggcggc 3169201 tggcaattag cagcgctgcg ctggtgtgcc aaggctgcca gcaaaccgat tatcgcggat 3169261 ggcggcatcc gcacccatgg cgacatcgca aaatcaatcc gattcggcgc aacgatggtc 3169321 atgatcggtt cactatttgc cggacacgaa gaatcgccag gccaaacgat cgaaaaagac 3169381 ggaaagcttt acaaggagta cttcggctca gcctctgaat tccaaaaagg cgaaaagaaa 3169441 aatgtcgaag gcaaaaaaat gcacgtggcg cataaaggct caatcaagga tacactgatt 3169501 gaaatggagc aggatcttca atcttctatt tcttatgcag gcggaacaaa gcttaacgcc 3169561 atccgcaatg tggattatgt gattgtgaag aattccattt ttaatgggga taaatattaa 3169621 tcataaaaaa acgccaagtc agcggttctc cgcttgagtt ggcgttttct gctacttctt 3169681 cagcaaagta agcttatatt tgctttttga gtttatcttc catcagttct gccatttgtt 3169741 ttgcatttgg attttcttca ttttgcaact gttcaatgac gttcatataa tccgtttcat 3169801 ttcggttctg gcttaattta tatgccgctt gaatgtcttc caccttaatc ttaaatccaa 3169861 caataccttt caattcactt tctaagagtt ttggagaaag cttatcccat aacacaggat 3169921 tgtcacgatg tttttcgtat ttctccaaca tgattgttaa ttcttctgct aattcatctt 3169981 tctctaacat acttgctttt ccatacatgt ggacagcctg ataattccac gtcggaacat 3170041 tttcgcgcga ataccaggaa gaagaaatat aagcgtgcgg tccctgaaac atcacaagca 3170101 catcttcaca ggcttcaaac gttctccact gaggatttcc ataagcgaaa tgccccgtaa 3170161 tatagtaatg atcgtctttt ttattgaatc ctaacggcaa atgtgtggca attggttttc 3170221 cttgttctgt tgtgacaacc gtaccaaagg agttttcttg tacaaaattc caaatttctt 3170281 cagcatttgt gactttaaaa tattttggaa tatacatcat catccaccct tcgaaaaata 3170341 ttatatgagt gttttagcca tgattaaatc cgtttgttct tcatcaccca tataaaatga 3170401 gtgggcgccg gtctgaacaa accccatttt cttataaaag gcaatggcat tttcattttt 3170461 ttcccacaca cctagccaaa tgttcttttt attacgttcc agcgcaattt ctatcgcttt 3170521 attcagcaga tgtttgccaa gcccatgttt ttgaaagctg ttctttatat aaattctctc 3170581 gatttcaagt gattcagcac ccatttcttc agactgagca tcatcgatat tgacctttac 3170641 atatccagcg atttcatgat caaagtaaat aaaaaagaat tgcgaagaca tattagataa 3170701 ctctttttcc agctgctcag tgttaaatgc gctttctaaa taggctttca tattttcagg 3170761 tgagttctgt tctttaaaag tgtcattgaa tgtttcaata ctcaattgtt gaagtgtttg 3170821 taaatcttcc cggctgcatt ttttcatttt tacactcatt gttcggattc agccccttta 3170881 tttaaaattc aattgtcttg tgtccctttt atatatttaa acacggaaca catactgacc 3170941 ttgttaccat tccaaaaatc ttcttcatca ccaactccct atcgtgattt tgttgtaaat 3171001 gcaataaaat atactccgca ttaaatatat cgtaactttg ctgtatttac aacaaaaatc 3171061 aaacaacaaa gcagcgtttc tcttgccgaa gttcccggaa ctctctgcat catttcccca 3171121 taataaaaac gcctccctta acgatgattt atcgctaaga aaagcgtcag taatagttgc 3171181 tatccgtttt tagtgcttag cactcttcag gcttgcctgc attcgttgct gttctgaacg 3171241 aagaaccgca gccgcatgaa gcgatggcgt ttggattgtc gatggtgaag ccgccgccga 3171301 gcatggattg tttataatca atcacggtgc cgttcatgat gtcaaggctt tctttgtcaa 3171361 ctagaacagt gatgccgtgc tgatcaaaca cactgtctga ttcactcttt tcatgctcaa 3171421 agcccatgcc gtaagaaagt ccgctgcagc cgccgccttt gacgcctaca cgcagaaacg 3171481 cgttttcttc ttcatgctct ttcatcatat cttttatatg caaagctgct gcttctgtaa 3171541 ttgttaccgg gttgctcatc attatgaacc tccttttaaa aaccggttgc tgtcttttat 3171601 tataaacatg atcgttccaa ttctcaaaca aggtgtttta caagaaatag acaccctcac 3171661 aaacggtttc agccggccct gtcatcatta catggccgtt atctttccag tttatcacca 3171721 aatccccgcc tgctaaatgc accgtgatgt cttgatttcg ctttgatacg ccgtttaata 3171781 cagatgcgac tgccgctgca catgctcctg tcccgcatgc ctgagtaatc cctgatcccc 3171841 gttcccagac gcggaaatgc aattcttgtt cattcacggt ttcaacgaat tccacattga 3171901 tgccttccgg aaatctcgga tctttctcaa tcaccggccc cagtgtcgtt aagggtgcct 3171961 gttcaatgtc tgcgatcgga aaaacgatat gcggatttcc cattgaaacg gcagtgcctg 3172021 ttagttctac ttcaccaaat gccatcgttt cattgattgt gtgctcttcc ccgccgtcaa 3172081 gcataggaag ctcggatttt gtcaagcgcg gttcgcccat atcgacagtg accacattca 3172141 cttttccgtt ttcgacttga acctccgctt tcacaagccc ggagagagtt tcaatcagaa 3172201 aagatgtttc ctcaaccagc ttatgctcat atgcgtattt tgcgacgcag cgcaggccgt 3172261 tgccgcagtt tttcccttca gacccgtcat tattaaaaat ccgcatttta acaggcgctt 3172321 ggtctgatgg gcatatcagg atcattccgt cggatccgat ccctgtataa acagaagaaa 3172381 cctgaattgc aatctctgac agtttttctt ctggaagctg ttcttcaaat tgattcacat 3172441 aaatataact gtttcccagg ccgtgcattt tggtaaatcg aaatgagttc ataggtgcct 3172501 ccaacttttt ttctttttct tagtataaaa gctattataa gcggacacaa tacaattatc 3172561 ccccgttttt catacataaa agctccttgc actgacgcaa ggagctttta tcgtttatat 3172621 aaacatgccg gcaatggctg cgctgagcag attggctaat gttcctgcaa gaacagcctt 3172681 caggccgaga cgtgcgatat ctgaacggcg gctgggcgct aaaccgccaa gcgtaccaag 3172741 cataatcgca attgatgaaa aattggcgaa tccgcataac gcgaaactga taatggtagc 3172801 agttttctta gaaaactcgc cgatgtgcga accgaagtta gaataagcga caaactcatt 3172861 cagcaccaat ttctggccga tatagcttcc cgcctgcaat gcttcatgcc aaggcacgcc 3172921 aatcaaaaag gcgataggag aaaacacata gccgagaatg gattctaatg ttacgccttt 3172981 taaaccgaac aagccgaaag ccccgccgag aataccgttt actacagcga ttaacgcaac 3173041 aaacgcaagc agcatcgccc caacatttaa cgcaatttgc agtcctgttg acgctccctt 3173101 tgcagctgcg tcaatgacat tggctgcgcc ttcgccttca tccattttga aatcgctttt 3173161 tacggtttgc gttttttccg tttcgggtat aatcaattta ccaaagacta gtccagctgg 3173221 agcagccata aagctggccg ccagcaagta ctcaatcgga ataccgagaa gcgcgtaccc 3173281 aaacaaggta gatcccgcaa ctgccgatag accgctcgtc ataatcgtaa acaactcaga 3173341 gcgcgtcagc ccggcaatca ggggtttgat cactaacgga gattctgatt gtcctacaaa 3173401 aatattggca gcagccgcca gagattccgt tttgcttgtt ccaaggagct tcgacaatcc 3173461 gccgccaatg acacggaaaa cgagctgcat gattttcaaa tgatataaaa ctgcaatcag 3173521 tgctgagaag aaaatgataa cgggcagtac acttaatgca aatgccggac tgtctccgac 3173581 ctttagaagc ggtccaaaaa taaaactgat gccttcattc gcatagtcaa tcagaagctg 3173641 tacacggctt gaaaaccata aaaaaacagc gcgtcccgct tcccatttca acacgatgta 3173701 tccaaacgcc acctgtgtgc ataaaccaac gatgacggtt cttatcttaa tattgctttt 3173761 cttttctgaa aataaaaacg cgatagcaat gatcgcaact gcgcccagca gcccccacag 3173821 aacattcatg aatactcgta cacctcttaa attttattta aaaaaatatc ttttatacga 3173881 taacaataat attttttgat gtctacacat ttttttagtt cttttgtacg gcaaaataaa 3173941 aaagggcctg tccaggccct tttctttaaa acattggatt ttcttcaata aaggtatata 3174001 tattctcaac aagctcagca ggcgtttcac ccatgacgac ttctccgttt accagagcga 3174061 aaagcgattc catacatgtc ccgcagtagc ttaagcagcc atattcaagg acatcaaggt 3174121 tgggatcctt ctccaaaatc gcccgggctt cctgagagcc gtgagccaga ttgctgacac 3174181 aaaattcaat cattggattc atgcggtttc acctcacata tgtccattat cgcgaatttt 3174241 tcactattcg tcaaagacaa cggatgattc aaaatttatt atcgtaacat attatttctc 3174301 aaataacgtt ttactaattt gtgttttcag gctaaattgt aggttatttt gaaactatta 3174361 ttgtgatttt agatcaaatt cgatataatt ctagatgtta ttttacatag ttcgtatttt 3174421 cttcaatgta tctatcatac tcttcggatt aaaggggaat tcaaatgaaa aaattggtct 3174481 tgatcggcgg aggttacggg aacatgcgcg ttcttcatcg cttattgcca aaccagctgc 3174541 ctgatgatgt ttcaatcacg ttaattgaca gaaatcctta tcactgcttg aaaacagaat 3174601 attatgccct tgccgcaggc acaatttctg accatcatat cagagtgtca ttcccagagc 3174661 accctcgcct ggatgtccaa tacggtgata tcacatcaat tgatattgta caaaaacaag 3174721 tgctgttcca agatcgtgaa ccgatttctt acgatgacgc cataatcggg ctcggctgtg 3174781 aggataaata tcacaacgtg ccgggagcgc ctgaattcac ctacagtatt caaaccatcg 3174841 atcagtcccg cgaaacctac caaaagctga ataatctgag cgctaatgcc accgtcgcca 3174901 ttgtcggagc gggcttaagc ggcgttgagc ttgcaagtga attgagagaa agccgtgatg 3174961 acctgaacat tattttgttc gaccgcggta atctcatttt atcaagcttt cccgagcgtt 3175021 taagcaaata tgtgcaaaaa tggttcgaag agcacggtgt ccgcattatt aacagggcaa 3175081 atatcacaaa agtagaagaa ggcgttgtgt ataaccacga tgatccgatt tctgcagacg 3175141 ccatcgtgtg gacagccggc atccagccaa acaaagtcgt cagagactta gatgtggaga 3175201 aggacgcaca agggcgtatt gtattaacgc ctcatcataa tcttccaggt gatgaacatc 3175261 tgtacgttgt cggcgattgc gccagtcttc ctcatgcacc gagcgcccag ctggcagagg 3175321 ctcaagcaga gcagattgtc caaatcttgc aaaaacgctg gaatggagaa gccctgcctg 3175381 aatcaatgcc gcagtttaag ctgaaaggcg tcctcggttc actcggaaaa aaagccggct 3175441 tcgggcttgt tgctgaccgt ccgctgatcg gccgtgttcc gcgtatgctg aaatccggct 3175501 tgctgtggat gtataaacac cataacggtt aatgatagag aagaaccgct gatcaagtca 3175561 gcggttttct gtatacccat gcttctccat ttcctcataa acgtctttta attttggatt 3175621 gccttcaccg acaattttgt cttctacaag cacaagcgga taaaaatact cgtcatttct 3175681 gattttttcc gcaagctctt tcgcatgttc attgtcaggc ggctcatgaa tatcgatgta 3175741 ctgcatctca aaaggctgat ttggatattt tcttttcagc gcagcctcaa gccactcgta 3175801 tgtatccttg gctgtcggca tatttacaca gctcgcacaa acgttttctg ccccgtacac 3175861 gcttagcatg actggtttca tcacttgtag acgccccctt ctcctatgta agtcctttct 3175921 tttaagtata cagagcctaa gggcgttttt atagaaaaaa accgtttttg tgttgaagtc 3175981 tgaatgtgct ataataggga aagcaacttt gcaaaccaaa caatagattt ttattgttac 3176041 actgaatata atggttttat gacgacgaaa ggagcgaatg tcatgactga agttgaaatg 3176101 aaagaacagg tgcaggaagt actggacaaa cttcgtccgt ttttacttcg tgacggcggt 3176161 gactgtgagc ttgtagacgt agatgaaggt atcgttaagc ttcgtcttct aggcgcatgc 3176221 ggcagctgcc caagttcaac aattacgttg aaagccggaa ttgagcgcgc tcttcttgaa 3176281 gaagtgccgg gtgtcgttga agtagaacaa gtcttttaat aaagcagcca ggctgatatt 3176341 tgatcagcct ggctttttta ttagagatgt tgatcaaacc atgagctgat ataattcagg 3176401 cgcttgatcc gctgtcttgg gtgtccggtg cgtgataaat tgtgcgatgc attcggaaaa 3176461 cggacaagct tggtttcctt gcccattttt ttcagagcga taaacagctg ctccgcctgc 3176521 tcgatcgggc atcggtcatc ccgctcgcca tgcagtatca aaagcggtgt ctccacgttt 3176581 gctgcgtatt ttaaaggaga ccggtcccag agcttttctg tgtcctcaaa catgtcatgc 3176641 tcaagctgcc agtctgtaaa gaaatagccg atatcactga cgccgtgaaa gctgatccaa 3176701 tttgatatcg agcgctgggt aacggcagct ttaaagcggt tcgtctgccc gacgatccag 3176761 ttggtcataa aacctccgta gcttccgccc gtgacaccga gccgcttagg atcaatatgc 3176821 ggatctcgtt tgatagcctc atccacagcc tgcatcacat cgtcataatc ctttccccca 3176881 taatctcctc tgaccgcatt cacaaattcc tgcccgtagc cgtggcttcc tctcggattg 3176941 atataaacga ccgcgtatcc tttcgccgcc agcacctgaa actcatgaaa atatgtatgt 3177001 ccgtacatca tatgcggacc gccgtgtatg ttaagaataa gtggatatgt tgtctcacct 3177061 tccatttgtg caggcctcat cagccagccg ttcaccatca cgccgtcttc tgtagcatat 3177121 tgaatctctt caggtattga tatcgtatgc tccctgacaa acttgtcatt cgcgccagtc 3177181 agctgtttct cttcctgtcc aagcgggata ctgtaaagct cactcggtct gtccggcttt 3177241 gtcacactgg caataaagtg ctgttcatca ggtgaaagag aaaagctatt gatgtactct 3177301 ttttccagac gaatcggata cacaaggcct tcaatcgaaa tataatagat gcccgtactg 3177361 ccttgatctg tgccgatgac ataaaaccct tggctgtcct ttgtccaaat cgggcgctgt 3177421 tcagcaccac cgatcaatga atctccaatc agcgcatccg ctaaatgaac gtccagcatc 3177481 tcagtaagac atgtgaggcg gccttgttcg atatcataga gccacgcctt tgagagcgta 3177541 gcattcttat attccttttc atttccaagc aaagcaagat accttccgtc tggtgaaaat 3177601 gagcttgatc cgaatgagcc gcgatgaggt gtaacctgct taagatctcc agactccagt 3177661 gacattatgt aaacatcatg cggcttgctg gcatcatctg tttcagttaa attagctgag 3177721 aaaacaagcc atttgccgtc aggagaaaaa gcaggatcac catgatcagc tttgtgactt 3177781 gtcagctctt tcatctcacc cgactttacg ctgacaagca caagctgggc atacgcacct 3177841 ctcgtcagcc ctttgccgtc ccgtttgtag gagaggcctt gcacttcaac aggttcatag 3177901 ctgtcctgct ctgttttttc tcggtcatca atgctttccc cctctcccaa actgacagtg 3177961 accagaatcg attcaccgtc cggggaccat agcggctttg acacgccata tgggatatca 3178021 gtcagttttc ttgcttctcc gccttcagtg ctcatgatat aaagctgtgc cgcatcgcct 3178081 tctcgatcag aaataaaggc aagcgtgcgc ccgtccggag accatcttgg gtcggtgctt 3178141 cgcttttctc catgtgtcca aggaacagat cctcccgttt tcgtttcata gatccatata 3178201 tttgatgtat acgaatcttt ctcttgattt acttgtgatt ttacatatgc ggcacgggta 3178261 ccgtctgggg cgtattgagg atcggtcaca gagacaatcg ctgtgatgtc gtctgcggtt 3178321 atcagctttt tcatattcat ctcctccttt ttacatgtat ttcgtttttc taaataaaaa 3178381 ctcctttatc tccagcaaaa aaaagcgccc tccgctgacg ctgaggaacg cttggcatga 3178441 tctatacact ttttacttga tataaaggat ttcgctctat tatacttccc tctttcggaa 3178501 cggtcaaagc gtctacttca caatgaggga aatgaagcgc gagctgttct tttagctctt 3178561 ctccctttcc tttttcggtc atgacgagaa tcgttgggcc tgctccgctg agagccgttc 3178621 catatgcgcc cttcatctcg gcgacgtgct ctacttttga cagctcaggc acaagcatcg 3178681 cccggtacgg ctgatggaac atatccttct tcatgatttt cccgacaagc ggccaatcct 3178741 tggacatgat cgcagcaatg aggatattgc tgacagcact tgcttttacg gcatcggcat 3178801 atggaaactc cttcggaagc acgtctctcg cgtctcttgt cagcacttca taaaaaggaa 3178861 tgacaacgac tacgtcaatg tcagcattcg ggacgcggat catttgggtc tcgtcatcct 3178921 catgcaggcc gatcacaagt ccgccgacga gagaagcgcc agcattgtcc gggtgtcctt 3178981 cttctagact cgctaaatgc agcttgtccg cttcagacag ctttaagccg cataattcat 3179041 cagccagttc aatggccgct acaatcgctg cggcgctgct gccaaggccg cgtgcaagcg 3179101 ggatgtcgct ccacaccttc acatggacag gaggcatttc ttttccgtac aaatctgcgg 3179161 tccgtttagc cacttggtag atcaggttat ctgtacccgc cggaattccg gcgactgttt 3179221 ctgtttcagc ctcaaaagac catttgtcgc tttcaaagac ggtcagcttc aaatatctgc 3179281 tgagcgccat tccgactgaa tcaaagccgg ggcctaggtt agctgtgctt ccgggaacag 3179341 tgacagagaa cagcatgtcg gcttcgttca tacacgggcc gctcctttta catattcaag 3179401 gatgctgtct tcatcagtcg gcaatgtgac aggcttgatt tctgaaatgt cgaccgctgt 3179461 gttcggatct ttcagtccgt ttcctgttaa cacagctacg accttgctgc ctttcggaat 3179521 ttctccggat ttcacctgtt tcagcactcc tgcgatagac gcgcaagaac ctggttctgc 3179581 aaacacgcct tctacacggg cgatcagctg atatgcgtga aggatttcat catcagtgac 3179641 ttcgtcaatt ttcccattgg attcctcggc tgcctttaca gctttgtccc agcttgccgg 3179701 gtttccgata cgaatggctg tcgctattgt ttccggattt tcaatcactt cattgcgcac 3179761 gattgccgcc gcaccctcag cttcaaagcc gcgcattttc ggaaggcctg tgccgttttt 3179821 ctcatgatat tccttgaagc ccttccagta cgcagtgatg tttccagcat ttccgaccgg 3179881 gatcgctaaa acatcaggcg cttcccccag ctgttcgcac acttcgaagg cagcagtttt 3179941 ttggccttca atgcggtaag ggttgactga gttgacaagg gcaatcggtg atttctcaca 3180001 gatggaacgg acaattttaa gcgcatcgtc aaagtttccg tcaattgcga taatctcggc 3180061 tccgtacatg acagcttgag cgagttttcc aaatgcaatt tttccgttcg ggatgatgac 3180121 aatgcatttc atgttagcac gggctgcata tgctgccgca gcagcggaag tgttacctgt 3180181 tgacgcgcac ataatcgtgt cattgccttc ttcttttgcc tttgccacag ccataaccat 3180241 tccgcgatct ttaaatgatc ccgtaggatt gacgccttcc gttttgacat gaagctcaat 3180301 tccgagctgc tcagacagct tcggcaggtg aataagaggt gtgtttcctt catgtaaagt 3180361 tagcgccggt gtttgatctg ttacaggtaa aaattcttta tattgatgga taagtccttt 3180421 ccacattagc tccaaccgtt cccttctaca cgatatgtgc ttttgacttc ttgaacgact 3180481 tccaaatcat ttaggttttg caggatatca ctgaaatcag cttctgatgt atgatgtgtg 3180541 acaattacga tttcagctaa ctcatcatgg cctttaattg gcagctgaag gattttttca 3180601 aagctcacgc cccgctctga gaacacagat gtaattttcg agaatgaacc aacctcatct 3180661 tttacatgaa ttcttaaaaa ctgctgtgca taaatgtcag acggcgattt catgtttttc 3180721 tcatattgcg gtccgacaaa gctgttgccg gttacaccta ggcgcatatt tttcatgaca 3180781 gcgacgaggt cagaaacaac ggatgtcgct gtcggcatgc ttccggctcc cggcccgtag 3180841 aacatcgtct caccgacagc ctcgccgtat acataaacag cgttaaactc attatgaaca 3180901 gcagaaagcg gatgatggtc aggaagcagt gtcggctgta cgctgacctc gattttgctg 3180961 ccgtcacgct gagcaatccc gatcagcttc attgtatagc cgaggcgttt gctgaagctg 3181021 atgtcctcgt ctgtaatttg ggagatcccc tttactttga cgtcttccag atccacgttc 3181081 atcgagaagc cgaggcgcgc caatatcgcc attttccgtg cggcgtcaag cccttccacg 3181141 tcagaagtcg gatcagcttc ggcaaaaccg agatcctgcg cttccttgag cacttcctcg 3181201 tatgggcttt tctctttgat cattttggtt aagataaagt ttgttgtgcc gttcacaatt 3181261 cccatcattt ttgtaattcg atctgatgag aggccttcct ctaacgtgcg cagaatcgga 3181321 atcccgccgg caacactggc ttcaaagtag atatcgcatc cattttcctt cgcttcggca 3181381 agcagctcgg agccgtacac agccattaag tccttgtttg ctgtgacaac atgctttttc 3181441 gatctcagcg cgtcgaccaa atattgtttt gtctgttcaa cgccgccgat cacctcgatg 3181501 acgacatcaa catctggatc atcaatgaca tcatacactt ctgtcgtgag cacttccttc 3181561 ggcaaatcta cttctctctt tttctctaaa tcttttacaa gcactttttt tatcgtaacc 3181621 ggacagccga cctgatgcat aagcttatcc tgatggtctt gaataatttt aacgacaccg 3181681 cttccgacgg tacctaaacc taaaagccct acacgaatcg ctttcaaaaa aactccacct 3181741 ttcttttgat tgtcctcttg gaaaagacaa ttgttaactc aacacagaca tataagttac 3181801 aaacattata taagcccgct cctgttttga caagacatca ttaggctgaa ttttgcgaat 3181861 gtaaacgctt aacgcattga tatgacaaga ttctttattt tctaattatt tttgtcagat 3181921 tttctcctca ccttgagctg cctttgccga gccagctgac gcgtggaaca aacagcttct 3181981 gcgcccgcat attcatgaat tcctgcgctg tattgagaaa ttgttcataa cgcccacagt 3182041 cattaagaat gaagtcaagc tgttcttcaa aataatgctt ttctgattct gatgacatgt 3182101 aatagctttc tacgatttca aaataatgaa gcgggaaaag cagacggctg tataaaaggc 3182161 gtttcgaaaa tgaagacagc ggtgtgactt gctcgtattc ctgtaaaaag agaaagccct 3182221 gctgattaaa atcttgtctg tgatgcaaaa acgtatgcct catatattca gccaaatcac 3182281 gggaagcgtg gtcaaacacc caatccgccg gaatcctgat caatgattcc ggtgaccatg 3182341 tatgcctttc catccgctga tggcatatcg ttcctgaatc agcggcttgg ggcttgtcat 3182401 ccagctcagt gtccactaaa tattgtatcg cgttttctga cagtcctaaa taatatggaa 3182461 atgattcgat cattttttta tcgaatggct catgcggagg ggtctgaacc tttctctgcc 3182521 aaaatgcttc cagctgatca attcgttttc cccacagatc cttccactgg ccgattcttc 3182581 cggccgcctt cacctcatat ggatatcctc ggccttttcg gtgaaattcc gcaagctccg 3182641 ctccaatgga gaacgccctg tttgaataag ggggggccgc cttcagcaga gcgtacgttt 3182701 ttccctcatg ttcaaatgtc agttcacctt cttttgtaaa gataaaaacc gaaacgtatg 3182761 ggtcactttg ttcttgtaaa tactgactca tgtaataaag ctccgccagc tctgtttctg 3182821 agaattggga aacggggaca atcagaaagt atgaattagg cgtctgaaag cattgatatg 3182881 tgtgctggta catggaaagc tgcctgatgt gaatgccgta tttttctttt attgtacctt 3182941 tcaccatgat cacctgcctg ttgaattagg gctcatcaca tcgtagtcat acacagccgg 3183001 aattatgaat acatatttta atccgaagaa ggcgcaagaa aaagtcgtaa acttctcaag 3183061 cattttgtat aaactagtaa aaaagattgg gtgaagctga tgtcagaaaa cgaacaattc 3183121 agtcagatgg aagctaaagc aagagcacgg atgaaggagc gcggcgttga ggtatcagac 3183181 attgccgagc ttgtcttttt tctgcagaaa aaatatcatc cggatttaac cattgatgaa 3183241 tgcacgctga acgtcaatcg tgttctcgca aaacgcgagg tgcaaaacgc gattttaacg 3183301 ggcattgaat tggatgttct tgctgagcag aaaaaattgt ctgaaccgct gcaaacgatg 3183361 ctggaaatag atgaaagcct atatggagta gatgaagttc tggcattttc cattgtgaac 3183421 atttacggat cgatcgggtt tacgaactac ggttacatcg acaaagaaaa acccggaatc 3183481 cttaaacgat tgaatgataa atcaaccggt gaatgccata cctttttaga tgacatcgtc 3183541 ggagcgattt ccgccgcggc ttcaagcaga cttgctcacc gcgcgcggca tacagaataa 3183601 gggcaccctt ttagggcgcc cttttttcaa atgtatggaa tccattcagt cagagagtca 3183661 atggcgtgag tcggtttttc catatcgtct gtcatatgtt ctcttttcgt tacgcctgtg 3183721 tgaacgagca gcgtatccat acccgcgtta atgccggcca taatatcagt ggcgtagttg 3183781 tcgccgacca tgagtgtttc agacacatct gtgccgagaa cgcgcatcgc ctgctccata 3183841 ataattgatt ccggcttgcc gataaataca ggctgtacac ctgtagatac ggttaacacc 3183901 gatgtcagtg agccgtttcc cggcaggagc cctctttcag tcggaatcgc aatatctccg 3183961 ttagtggaaa taaagcgggc gccatttctg attgccaggc agccaacagc aaatttttcg 3184021 tatgtaatgg aacggtcgat gccaacaacg acaaaatccg cgttttctcc gccaaatgtc 3184081 aggccgtttt cttcaatcgc ctggcggatt ccttcctccc caatcacata cacagacgcg 3184141 tcttttttct gctgtgcaat gtgctgggca gttgccatgc tggtcgtgaa gacctgctct 3184201 tctgttgccg gaatatcaaa agacacgagc ttgtccgcta cctgcttcgg tgtgcgcgaa 3184261 gagttgtttg tcacgaaaag ataaggaacg ccgcgatctt tcagcgttct gacaaattca 3184321 cacgcctcct cgattttttc cgtgccattg tacatcgttc cgtctaaatc aattaaatac 3184381 cctttatatg ttttcatatc caacactcct gtggctttcc agttgttatt taaacgcgga 3184441 aacaggtcct agctctgttt ccaaatagct tctgatccgt ttcgggaagt cctgaagagc 3184501 tgtttgatgc gccttgatca gcctgtaaag ctcgccgctg tcagcgagca gatactgttg 3184561 aaccaacgtt ttgcggtagg cgatcaattt tttgagctca tcaccctctt tttccgtgac 3184621 aactttctca tcaacaagta tatccataat gtcgtcatag ctgcccgggt cccgcataat 3184681 aaagccgtca atcatgtcat tgcctgtatc caaaatgcat tcgattaaca gatggcctat 3184741 acgctgaagt gccaattccc cgatttcaga ctgccagtct gtttgtgagt caaatagcgc 3184801 cagctggtgc tcgaagaacc ctagtgtttt ttcgattttg cttctgtcaa caaaatacat 3184861 gacagcatcc cctttgtgta tatttatttt ctgatccgtt tcaagacaaa atacgcacag 3184921 ccgaaattgc agtattcgta aatatattca tctaatgtgc tgattttcgt ttcgaaggtt 3184981 gccttttgat tctggtcgtc aaagaagccc ttgagcctta actgaccgta tccccagtct 3185041 cccacaatat aatcgtattt atttaatata tcggagtagc gggctttaaa agcctcttcg 3185101 ttgaagccgt ctttgaaatt gtgcaccaat tcaaattcgg cattttgaat aagaatcatg 3185161 atctcacctc ttttttcact cattcctatc ataattcatt gccccgtccc catcaattgc 3185221 taaagaataa atcatgcgat ttggctaccc tacacatgag gagggattga taaatgaaac 3185281 gaaccgctgt cagcctctgc ctgctgaccg gactattatc cgggtgcgga ggcgcaggat 3185341 tggataatgc ccaaaatgtc cggaatcaga cgcagaatca aaccaaaccc attcatgtgt 3185401 cggaccgcaa cgaggctttt aacaggcata atgagaacga acaatttggc tatgtccgct 3185461 atcaaaaaga acaatttgac ggagaacagc agaaaacgcc ggtgatgaac cgggaagaaa 3185521 ccgctcacat gatatcaagt ttaacggttc agctccccca tattcaagat gctgcgacat 3185581 tggtgactga ccgagaagcg cttgtcgtat acaaaaccga ttctaaaaac cgggagctga 3185641 ccgccgatca ggtgaaaaaa acagcggctt ctgtgatacc gcgatactat cacgtgtata 3185701 tttccgataa tccaaaccat atgcaatccg tcgaaaatta cagcaatctc ggctctggtt 3185761 caagggatat tagagagatc atgtcgggga cgattcaaga aatgaaaacc tccccgcaag 3185821 gaagccctgt ctcagagaat gaaaatgcca atggagaaac gcgtcaggac atgaaaatcg 3185881 ataggaatga caaaaacgcc agatgatctg gcgttttggc attatgcttg tgcttgacgc 3185941 tttttagatg cttcgtttac ttgttcatcc gcatggtaag aggaacggac aagcggaccg 3186001 gcttcacaat ggctgaagcc tttttgcatc gcgatttctt ttaattctgc aaattcatca 3186061 ggatggtagt atttttggac tttcaagtgt ttcttcgtcg gctgcagata ttggccgatt 3186121 gccataatat ccacgttgtt cgccaagagg tcgtccatta cttcaataat ctcttctttt 3186181 gtttcgccga gtccgatcat gatacttgat tttgtcggaa tgtcaggctg catttccttc 3186241 gcacggcgca aaaattccaa tgaacggtcg tacgtcgcac gcgcgcggac tcttggcgtc 3186301 aggcggcgaa ccgtttcgat attgtgattc aggatgtctg ggcgtgtatc catcaaggtt 3186361 tttaggttat cgtagtttcc gcccatatca gacggcagca cctcaattgt tgtgaacggg 3186421 ctttttctgc ggatcgcacg gacagtttcc gcgaaaatgc ctgccccgcc atctttctga 3186481 tcgtcacgcg caacagccgt aatgaccgcg tgtttcaaat tcataagcgc gactgaatcc 3186541 gctacgcgtt ccggctcttg cagatcaagc tcagttggaa ggcctgtttt gacagcacag 3186601 aaacggcatg ctcttgtaca aacagaacct aaaatcataa atgtcgctgt acgtctgacc 3186661 gcccagcatt catgaatatt cggacacttt gcttcttcgc atacggtatg caggttgttt 3186721 tcccgcatga gttttttgag ccctgtatag ttttcatttg tatttaattt aattttaagc 3186781 cattcgggct ttctgaggtg ttcgtctttc tttgccaatt cccatcatct ccaatatcca 3186841 atatactcaa tttctgacac gaaacattct gaaaacgaga aaggtgcagg ttttagttct 3186901 gcaacaaaaa taatgttttt ctaactaaag aaagtctttt ctttagacac tttaacatag 3186961 gaaaaatttc tcgacaaggg aagatgatta ctgacatttt taagccgggt tgccgcaaac 3187021 tatgtgtatt caatatgaaa ggagattatt ttgtgaaagt tttgttatcc gctcttcttc 3187081 tccttttgtt tgcatttgag ccttctgcgt ctggaaaaaa actttcagat ccagtgctgt 3187141 cgaaacggat ggaattatat cataaaatcg aagctgtgac gcagatccct tggtatgcgc 3187201 tcgccgctgt tgatcaatac gaagaaaacg tgcggagcaa ccggaaagat ctgcctgaaa 3187261 aggcgggaat catcagcatc tatatacccg atgatatctg gagcgggcct gaaaacccga 3187321 atccgaaaga cgatgcgccg ttaagcatta aagtgtttga cggaatcgga atggatggcg 3187381 atggagacgg gaaagccgag gtcagcaacg atgaagatat cttgtatacg ttcagccaat 3187441 acttactgtc gtatggcaca gatgaagaca acatccggat cgggctttgg aattattacc 3187501 ggcgtgatca gacagtgggg attatatctg aattcatgaa gctgtttaaa gcctacggcc 3187561 atattgatct gggcgagcat gcattcccgc ttccgatcag aaccgattac agctaccgaa 3187621 gcacgtgggg agatgcccgc ggcttcggtg gaaggcggat tcatgaaggt acggatatct 3187681 ttgcccatta cggccttcct gtcaaatcca catgttacgg cgtagttgaa atgaagggct 3187741 ggaaccgctt cggaggatgg agaatcggca tcagggacat taacaatacg tatcattatt 3187801 ttgcccatct caatgggttt gccaaaggga ttaaaacagg acaaatcgtt gagcctggcc 3187861 aagtgatcgg atcagtcggc agctccggat acggcccgcc gggaaccgcc gggaagttcc 3187921 cgccgcatct gcactatggc atgtacaaag ataacggaag aaccgaatgg tcatttgatc 3187981 catacccgca tttgagggcg tgggagcgat atgaatacca aaaaaagaag taacaaaaag 3188041 ccgcctcttc aacaggcggc ttatttgctg cttttttctt tttttgaatc ggcaccgttt 3188101 tctttgctgc tcggaagctg gacagaaggc gtgacacccg agccgccgct tccattataa 3188161 aactgcggca cttcgccctg cactgcttta atcgatacag gaacattatt tgtgacgaca 3188221 gcggttttgc tggcaaatgg aatgatgacc ttcactttaa tttcgacaaa gatgctgata 3188281 tcaataagtg cgttatttat gccatacggc ttgattttgg ttttgacatc tgtaaaagcg 3188341 tcaccgatta aattgaaccg gaccgggatt ttcggcccga ggtttccaag aaggctgttg 3188401 ccggttacct gtcccagcgg aatgttgatc ataatgtttt cactggcgcc gctgtgtccg 3188461 gtatgggttt ccatctcttt caaatgagcc tgaagctgct ttgtcacttt tgttttcaca 3188521 ctgtttacaa cctgtgtatt aaaatcgatt gtcgttaagt ttccgttttc atcagaattc 3188581 atttgaaaca tatctttcat attttcactg tcagacatat agtcctcaat cgaatcctgg 3188641 atcacctctg tcgctatacg cttcgtttcc atctcgccga tgtccattaa aacaggtttg 3188701 atcgagccat tgatcatcca aaggctgacc gttgttgaca ggataaaaaa gacaacggac 3188761 aggagcatca cgtaacggaa aggcaaaggt cctctcttgc gaaaagggcc gcgatatctt 3188821 ggcaagaaaa tcccccctta catatcacaa tgtatgcttg taagagggga catagtaata 3188881 gccggggcca atttatttta tttcatcatt tttaaaagcg cttctctgcc gctcatgccg 3188941 actttgatgc caagatcttc cgcagcgtac gtgacggatt ctaaaggtgc gtctaacagc 3189001 tggtcaatgg tgcggacacc aactgcgcgt cccgccacga tgccgcgctc ctttaatttt 3189061 tcattcagca gcgccacatc aagcgcgccg cacataatgt atccgtgatc attggcgacg 3189121 gccataaaat tcgttttggg aagctttact gtcacagctg taaaaggctg tccttctatc 3189181 atgatcggtg tcaggtttac cacgtcaacc actcccttca ttcatcactt tatgatgaag 3189241 ggcacagctt gttgtgggct gactgcctta ttgtgcaagc ttccaagcaa gcagatcccg 3189301 caaaaattcc ggcataaaat attctttttc tgcagcgtcg cgaatcaacg gaaacagttt 3189361 gccgagcgta aacatatcaa gcaccgcaac ggagtattgt ttatgttttt caatatcttc 3189421 cccgttcagt gtgatccgag tgacgtgggt gatcccgtca tcgagccgtt tcgtttctac 3189481 ctcaacgccg gcatacacca ttttccccat cacttctccg cggaagccga gtcctttgat 3189541 ccggagctgc tccatttgtt cggaagcggc atggacaatg gtttccttca gttcttctcc 3189601 cgtcaggcgg acagccaccg ggttgatcgg atgcggacag atgcggtgca gatccagctt 3189661 tgtcacagga cctgctttta gcggaccgag aatgacacct gaattgacca tactgatgtc 3189721 cgtctcgcac cattccttta aggcgtatgc caaaagcaaa ggcagctctg attcttcaaa 3189781 ccacttcacc tcagcatctt gtgcaagctc tgcaacggca tcggacagtt tctcctcggc 3189841 ttcacgttct ttttcattga gaaacgcttt agtttctgcg gattctcctg tccattccgc 3189901 catgttctgc acagaagccg ttttgctgtt gatgcttcgc tgtacgctgt ccaccgtgat 3189961 ttctacacag ccgacataat gcccgtattt ctcggcgctg gccagcagta ccccattaac 3190021 cacttgtcca tcttcgagca aatgatgggt atgtgattcg aggattacat caatctcagg 3190081 caccgcttca gccactgctt gatcatcaag aatgcctaaa tgtgacagca gaacgataat 3190141 atcagcctgc cctttcactt ccagaatggt ttcctttatg ctttcaaggg catccgtaac 3190201 tgtccatccc agcttgtcat atacaggata atacggcaca gttacaccta agaaagcaat 3190261 ggacataccg tttttcaatg atttgatatg gtaaggcacc gcccaggacg gacggtttcc 3190321 atttttatca aacaggttag agacgatgac aggaaattca gcatgatcat ataaggcagc 3190381 aagctcttca tgcggaagcg taatcccttc gttattgccg atcgccgctc catcaatgtg 3190441 aaggcggttt aagagatcga cattcgcttt tccgaatgtc gcctctgtca cgaattgaaa 3190501 acgatcaaga tgatcgccaa tatcaaaaac gagcgtctct tcgccgtctg actgatgctc 3190561 ttttcttttc tgctcgatat aatctacaat tttcggccag ttttcaaaat ggctgtgcaa 3190621 atcatttgta tgatataagc ggagcttctc cttcataata tctctcccta atcgttcagc 3190681 tgaaaatgcc ttcataaatg agctggcagc cgatcaaaat caatacgatc cgcatgatca 3190741 taacgatcgt tttcgtctgc atttttctgt tgatggcggc gccaagcttt ccgccgaacc 3190801 aagcgccggg cacaagcgcg agggcgtaca gccaattgac gtgcccggaa atcatatgtg 3190861 aaacagaccc tgtcatagaa gacaggaaaa taataaacat ggacgttgcc accgcaacct 3190921 tcggcggaaa cagaaataac agcatcatcg ccggaaccat cagtgatccg ccgcctatac 3190981 cgaaaagtcc gcctaaaaaa ccgacaacaa aggcaatggc aataccgaca gaggcctgat 3191041 atgagtacgt ataaggctca ccggcatcat cctgaaatgt ccggataatt cctttgtgcg 3191101 ctttgttgat tggccgggct ttcgctttca gcattaagga taatgaaatc agaatcataa 3191161 aaatgccaaa ccaaacggaa aacgagtttg aattgaacag ctttgacacg taagccccga 3191221 tcatgctgcc gggacccgaa ccgataaaga aaatgagtcc gctcttataa tcaactgttt 3191281 tatatttaat ataagccaaa gttgaagaaa ggcccgtaaa aataatgacc aaaagcgaag 3191341 ttccaatcgc aacctgcggc gtcacatcct gaaacagctg cgtcactgtg cttaaaaaca 3191401 tcagagatgg cacaatgaca attccgccgc caagcccgat cagacttcct accgtacctg 3191461 cgattaatcc cagtacgacc aaaatcacaa acgacatcaa tcaaaacctc ttttctaaaa 3191521 taaatcgagc tgtctcggag caagtccgct gtactcgata tcaagcagtt caagcatctg 3191581 cttgccatta tccgcagcgt caccgccgga attgttgttg aacaggacaa aaacatcctt 3191641 acattgctgc tgcaattcat tcaggtgctt tttccaatcc tccagctcct gttggttgta 3191701 gcggtataag tacctgacct cccgccagtt tttcccgcca tcaggcttca tccagccctg 3191761 cttgttgcgt ccgtgaaacc tgacgagcgt tttgttttca tcggtcgcgc gcaacacggt 3191821 cggaacgctg ccttctccga tttgcggttc atcacagaca ctgtgaatcc agccttccgc 3191881 tttcataaat gaaagcgtct gctcataaaa tggcggcgag aaccaggaac ggtttctgaa 3191941 ttcaagcgcg caaggaatat ctcccatttg gtgcttacac catctcaaat aggcgacatt 3192001 ctccttcttg cagtcaaacc acggcggaaa ttgaaacagc accatggcga gcttattgct 3192061 atgtaaatat ggcgttaaag acaccttaaa cgcatcaaac atctcctctt ttgagtcaaa 3192121 gggaatttcg ccgcgctgat gccctgtcat gccctgatat gctttcacga taaattggaa 3192181 ggtttcgggc gtttccttca cccacttttc attattgcgc gccggctgaa tcgcgtaaaa 3192241 gctcgcgtct aattccacga tcggaaaatg ggaggaatag gcctgcaatt ttttctggct 3192301 ggccgttttc ggcggataga tgctgtcatg atccccccat cccgtcagtc cgatataaat 3192361 cacactcatt cacctctctt ccagtttatc acacgtgttt tcaggtttcc tcggaaatgc 3192421 tgttcatatg gcgggaaaat gcctcacgca aatgctgata ttgttcctca ttcgtatcta 3192481 aaaacgcctc ttctcttgag gaaggaatgt gctgatattc aataggcgcc tgaaactgct 3192541 cactcgtaaa atcgtacacc acaccattga tgctgttata aaaatgccag ctctcatcga 3192601 ctcttgtttt gaaaatcgtg ccgccgaaat ggtcttgaat caccaatgcc gtcacgccgc 3192661 attggccgca tgacgggcat tcttccgtcc atttagagct cgaatggcgc gaccaggatt 3192721 gcttaagtat gtatttgaca tgctccattg cctccgcctc ctttaaaaaa agataccacg 3192781 ttgatgagat tttaaaaact agaacggagg aaatcaaaaa acccggcggt aaaatccgcc 3192841 gggcttacga aggaacgacc agagctccgt caatttcagt gactttttcc ccatcattgt 3192901 acacgcaccg gcctttgctg taagtggccg aaatgctgca gggaaatgta tgtccttcgt 3192961 aaatgctttt tttatgcttt gcaaacatcg attctcttgt aacagtgtac ggctccatgc 3193021 tgacgagcac gaaatctgca tcacaccccg cctcaagccg cccttttttc tgaaggccga 3193081 atcgttttgc aggggccgcc gctgtccatt ctgcgatggt ttcaaatgga atctgatgct 3193141 caagcgccag ttccagcatt cctaataaag tgaactgccc gccgctgatt ccgccccatg 3193201 ataaaaacat gttatcctcc cgcttcaagg atggacggca aggggaatgg tctgaggaaa 3193261 ccatgtcaat gtccccggca atgagcgtct cgatcagcgt ctcttttgat tgccgtgacc 3193321 ggagcggagg cgcgcatttt gcgacagagc ccctttgccg taaatcgtca tggctgaaca 3193381 agacataatg cggacatgtt tcaaccgaaa catcaagacc ttcctgtttc gcctctctga 3193441 tcagccggac cgctttcgcc gtgctgatat ggacaaaatg aaccggacag cctgtcacct 3193501 tcgcatactg aatcgtgcga tacaccgctt caacttctgc ttcctccggg cgggaggcgg 3193561 cgtacgcatc cgcatccacc tttcctttat tggccaaaac catctgcaag tagcttgtga 3193621 tcgcgtcgct ttccgcgtgg agagcgagga tttttcctgc agccgcgatt tctgccatgc 3193681 ctttgagcaa tgtccgttca tcaacagagc ggaactcatc agtgcctgac tttgataaaa 3193741 acgctttaaa cccgatcgct cccgcttcag ccatcggacg gatgtcctcg atatggcctg 3193801 gcacaaggcc gccccatagc gcaaaatcca cggcagattt ttgcctgcct agctcagctt 3193861 ttgcgagaag atgctctgcc gtcacggttg atggaataca gttgagcggc atatcaaaat 3193921 aggtagtgca accgcctgcg gccatcattt gagaacctgt ttcaaacccc tcccaatcct 3193981 ccctgcccgg ttcattaaaa tgaacatggc aatctatcac accaggaaac acgtatttcc 3194041 cgtctgcctg gatgatttcc gtcccgcttg cttcaatgtc agaacctatc tcggcaatga 3194101 caccgttttg aactacaata tcagcttcta taacgccatc tggcgtaact gccttcgcac 3194161 cttttatcac catatcgtaa gccatattga tccccccatg tcaggatgac gattttccat 3194221 gtcagtttat gtaacacaac cagttctatt ttcaacagtt tactgctact atgatcgtat 3194281 tacatcagca aaaccgctag aattcctatt gaaaattatt caccttaacc aatgttttta 3194341 tagaaaagga gaatgcgcta tgaatattct tgatgtgatg aaaataccgg cttttgaaaa 3194401 cgccaattta atcgctggaa aagcaggagg ggaaagagag gttcagcatg tcaatatgat 3194461 ggacgctccg gatatcgtag actttttgca taagaatgaa ttgctcgtca ccaccgccta 3194521 tcacctgaag gatcacccgc atcaattatc tgaactgatt cggcaaatgg caaaacgcgg 3194581 ctgcgcgggc ctcggcatta aaacaaagcg ctatctggaa gatatcccga aggaaatcat 3194641 cgaactggcc gattcatatg cgtttccgat cattgagctt ccggaacaca tccgactcgg 3194701 cgatattgtg aatgccacac tcagccatat tctcgatatg cgttctaacg agctgcagca 3194761 agccatttac gcgcacaaaa aattcacaaa ccacattatg agcggcaagg ggctgcaatc 3194821 cctcctcaaa aaggtgtcag acatccttca gcttcccgtg ctgctgcttg accagcatgc 3194881 caaaatgctg tctgcgtctc atcagatttc agttgagacc gaaaagctga aaggcaccct 3194941 gaataccgta tccgggccat ttttcacttg tttctctaca atctcagatc agaaaacata 3195001 ttctgtcctg cctatttata atcacgaaaa aaactgcggc tacctgctga tacccgacat 3195061 ggtgcaggca ggcgacaaag gattgatcct cacgattgaa caagcggcca acgtcatttc 3195121 ctttgaactg ctgaaggaaa atgcgctgaa gcagttcagc cggcgggccc gcaatgagtt 3195181 tttcaacaat tttattgagc ggaccttttc ttcagatgac gaaatcaaaa accgggcgaa 3195241 agaattcaag ctgcgctggg atcaaaaata catgtgcatc gccggcaaac tcgatcgcaa 3195301 tgacgaatca atcagcttta cagaaaatca gctcgcttcc gacagcgtat tcgaatttct 3195361 tgaaggtgaa ttatcagcct tcccgtttcc acctcacttc tttatgaaag gaaatgtcgg 3195421 cattattcta atcgaggcga cagacagctg gagtgaaatg cacgcctcgg tgatcagctt 3195481 tttagaacag tttcaaacac aggtcagcgc tcaatttaaa cgaaccgtgt cctttggcat 3195541 cagcaatatc tgccaaaagc tcattgatgt tcccgacgct ttcacagaag cttctgatgc 3195601 tctgcaatcg gggcatttgt caagaagcac cgcatttatc caggtgtatc acgccaaaga 3195661 tgtgcctgag cttctgcgct tgctcccagt tgaggatttg aagaaatttt acaactccac 3195721 gcttcagagc ctcgctgaaa aacagcagga ggatcaaagc ctgcttcata cgctttccgt 3195781 ctatttagag acacactgcc aaatttcaga gacggcaaag cgtctgtacg ttcatcgcaa 3195841 tacggtcata taccgccttg aaaaatgcga agagcttctg gggaaaagct taaaagatcc 3195901 tgaaacaacg atgcgtttgc ggcttgcatt acgtatgcag cggctgatca gctaaagttt 3195961 gttacatttt cttacaaaac gaatcgtttt tcgtcacttt cagcaatcac acctgtcttt 3196021 ttcagctact gtatccaatg acacccctcg accggaacga tattatgtta ctaaagttca 3196081 catacaggga gggactatag tgaaaaaaag atcgtttaag gtgtttacac ttagcctgca 3196141 gcatgtgctc gccatgtatg caggtgcgat tttggtgccc ctgcttgtcg gcagggcgct 3196201 gaatgtaaca actgaacagc tgtcctacct attggcgatt gacctgttaa catgcggcgt 3196261 cgctacgctt ttgcaaacct tgcgcggaac atacatcggc atcgggcttc ccgtcatgct 3196321 tggcagttca tttgtggccg tcaccccaat gattgcaatc ggcagcaatt acggcattca 3196381 cgcgatttat ggttccatca ttgcggccgg tgtgttcatc tttttgtttg cgcgtttttt 3196441 cggcaagctg actgtgttat ttcctcctgt cgtaacaggt accgttgtga ccttgatcgg 3196501 cctttcactt gttccgacag gtgtgaaaaa tatggctggc ggcgaaaaaa taaacggcag 3196561 cgccaacccc gaatacggtt cgctcgaaaa ccttcttctc tctgtcggtg tccttgttct 3196621 gatcttagtc ctcaaccgct ttctcaaagg atttgcccga acactgtccg ttctgatcgg 3196681 catcgccgcc ggaacagcgg cagcagcgat catgggcaaa gtcagctttt cttctgttac 3196741 agaagcaccg ttcttccaaa tcccgaagcc tttttacttc ggagcccctg cgtttgaaat 3196801 cggtccgatc ttaacgatgc tgatcgtcgg aatcgtcatt attgtggaat caaccggcgt 3196861 tttttacgca atcggaaaga tatgcggcag acctttaact gacaaagatc tcgtcaaagg 3196921 ctatcgagcg gaaggaatcg ccattctcat cggcgggctg ttcaatgcct ttccttataa 3196981 tacctttgcg caaaacgccg gcttattgca gctgaccaaa gtgaaaacaa gaaacatcgt 3197041 cgttaccgca ggctgtatcc ttgtctgtct cggactgatt ccgaagattg ccgcccttgc 3197101 atctgccgtt cctgctgctg tacttggcgg cgcgaccgtc gtcatgttcg gcatggtgat 3197161 tgcctccggc gtcaaaatgc tcagcacagc ggatctcaaa aatcaatacc acctcctgac 3197221 catcgcatgc tcaatcgcac tcggcatcgg cgccagcacg gcccccggga tttttgctga 3197281 attccccgct ccgatccgga ttctggtcag tgacggcacc atcaccggaa gcctaaccgc 3197341 catctttttg aatctatttt tcagcttgcg cgacaaaaaa gaattaacag cacagcaaac 3197401 agaacttccg gtattagaac atacactcgc attagaaaaa gaggtgtaaa aaagatgaag 3197461 gaacagcaca atgccttaca gctaatgatg ctggggcttc agcacatgct tgccatgtat 3197521 gcgggagcca ttctcgttcc gttgatcgtc ggagcagcga tcgggctgaa tgcggggcag 3197581 ctgacgtatt taatcgcgat tgatttgttt atgtgcgggg cggcaactct tttgcagctc 3197641 tggagaaacc gatatttcgg catcggcctt cccgttgtgc tcggatgcac gtttaccgca 3197701 gtcggcccga tgatttccat cggaagcact tacggtgtcc cagcgatata tggtgccatt 3197761 atcgccgcag gactgattgt cgtcttagcc gcgggcttct tcgggaagct tgtccgtttt 3197821 tttccgcctg tcgtaaccgg atcagtcgtc atgatcatcg gcatcagcct gattccaacg 3197881 gcaatgaata acctggccgg aggtgaagga agcaaagaat tcggctcact cgacaacgtg 3197941 ctcctcgggt ttggcgtcac agcttttatc ttattgctgt tttatttctt taaaggcttt 3198001 atccgctcca tagcgatttt actcggtctt atcgcaggaa cagcggctgc atatttcatg 3198061 ggaaaggtcg atttttctga ggttttggag gcgtcttggc ttcatgttcc gtctctgttt 3198121 tatttcggac cgccaacctt tgagctgccg gctgttgtca cgatgcttct cgttgcaatt 3198181 gtcagcctcg ttgaatcgac aggcgtttat tttgccctcg ctgatatcac aaaccgcagg 3198241 ctgtcggaga aggatctgga aaaaggctac cgggcagaag gccttgcgat tttgctgggc 3198301 ggcttattta acgcgtttcc ctatacagct ttctcgcaga atgtcggcat cgttcagctc 3198361 tcaaagatga aaagtgtcaa cgtcatcgcc atcacaggaa tcatactggt cgcgatcggg 3198421 ctggttccaa aagcagcggc cctgacaaca gtgatcccca ccccagttct cggcggcgca 3198481 atgatcgtca tgttcggcat ggtcatttct tacgggatca aaatgctatc cagcgttgac 3198541 cttgattcgc aaggcaacct gctgattatc gcctcttccg tcagcttggg gcttggcgct 3198601 acaacagttc ccgcgttgtt ttcatctctt tcgggcgcgg cctctgtctt ggcaggaagc 3198661 ggaattgtga tcggcagttt gacggccatt gcactgcacg ctttttttca aaccaaacag 3198721 ccgaatagcg cagacataaa aacgtaaagg aagatgccaa tgttcacaat ggatgacctg 3198781 aaccaaatgg acacacaaac actgacagac acacttggct ctatttttga acactcttca 3198841 tggattgcgg agagatccgc agcactacgg ccgttttcgt ccctttctga tcttcaccgc 3198901 aaaatgactg gcattgtaaa agctgcggat cgcgagacac agcttgattt aatcaaaaag 3198961 catccccggc tcggaacaaa gaaaacaatg agcgatgact cggtacgaga gcagcagaac 3199021 gcagggctcg gcaaattaga acagcaggaa tacgaggagt ttctcatgct gaatgaacac 3199081 tattatgatc gcttcggctt tccttttatt ttagcggtga agggaaagac gaaacaggac 3199141 attcaccaag ccctgctggc aaggcttgag agcgaacgag aaacggagtt ccagcaggcc 3199201 cttatagaaa tttaccgaat cgcccgcttt cgtctggctg acatcatcac tgaaaaagga 3199261 gagacgcaaa tgaaaagaac catgtcttat ggcaaaggaa atgtatttgc ataccgaacg 3199321 tatttaaaac cgctcactgg agtgaagcaa atcccggaat catcttttgc cggaagagat 3199381 aataccgttg tcggcgttga tgtgacatgc gaaattggcg gagaagcctt cctgccatca 3199441 tttacagacg gagacaacac tctcgtcgtg gcaacggatt caatgaaaaa ctttatccag 3199501 cgccatctcg catcctatga aggaacgaca accgaggggt tcctacacta tgtagctcac 3199561 cgatttttag atacctattc tcatatggac acgatcactc tgactggcga agacattccg 3199621 tttgaagcaa tgcctgcata cgaggagaaa gagctcagca caagccgcct cgtcttcaga 3199681 agatcgcgta atgaacgaag ccgctctgtg ctgaaagcag aacgaagcgg gaataccata 3199741 acgattacag agcaatacag cgaaatcatg gatcttcagc tcgtcaaggt gagcggcaac 3199801 tccttcgtcg gcttcatccg ggacgaatat acgactctcc cggaagacgg caaccgcccg 3199861 ctgtttgtct atttaaacat cagctggcaa tatgaaaata caaatgactc atacgcttct 3199921 gatccagcac gctacgttgc ggctgaacaa gtccgcgact tagcgagcac cgtttttcac 3199981 gagctcgaaa ccccttcaat ccaaaaccta atctatcata tcggctgcag aatattagcg 3200041 aggttcccgc agctcactga tgtcagcttc caatctcaaa atcacacgtg ggatacggtt 3200101 gtcgaagaaa tcccgggctc aaaaggaaaa gtctacaccg aaccgcgccc gccatacggt 3200161 ttccaacatt ttaccgtgac aagagaagac gccgagaaag aaaaacagaa agccgctgaa 3200221 aaatgtcgga gcctgaaagc ctgatgggaa aactgacaac ccatatttta gatttaacct 3200281 gcggcaaacc agcggcgaac gtaaaaattg gattgaagcg gctgggcgaa agtattatga 3200341 aagaggtata cactaacaat gacggcaggg tcgatgtccc tctgctggct ggtgaagagc 3200401 tgatgtcagg agagtatgtg atggaatttc atgcaggaga ctattttgcg agtaaaaaca 3200461 tgaacgcagc cgatcagccg tttttaacca tcgtcaccgt ccgttttcag ctagcagatc 3200521 cagatgcaca ttatcatatc ccgctcttgc tgtcgccgtt tggttatcag gtgtataggg 3200581 ggagttaaga aggaagcccg cctcaccggc gggcttcttt ttgcacttca attaactttt 3200641 gatcctagga cagtacttga agtgatcccc acacttagtg aaacaacagc tagaataaac 3200701 attcacctat atttttcagg ataattgcct acgagaaaaa taccctgtag tcctttcatt 3200761 tataaatcga ggtttcaaac taataagtca gctcttagca gccgagctcc cttctccaat 3200821 cctataaaca gaccgcgttt tttctcgaaa aaatactctg aagacaattg ctgcgttttt 3200881 aatagttttg ataacgcgtt ctctcttaca cctttagaca aaatattcat tttttctttt 3200941 ttagacttaa atctatgtcg aaaataatcg ttggcatatc ttatcctatc tccactaaag 3201001 gaggtgacat tatgggattc tacaattctg gtggatacag tggaaactct ggttactcaa 3201061 acggtttcgg gagctccttc gctttgatcg tggtgctatt cattttgttg atcattgttg 3201121 gagcagctat ctttaattat taagtttaac tttccttgcc tccgccgtat ccaacacctc 3201181 cctgtccgac agacgccata agaagttttt atggcgtctt tgctatgtgt tcactaatct 3201241 ttttgtaatc cagaagctgt caagttctac gagatttatc gtgtgttttc ccacaacgct 3201301 tctgcgtctt gatcgcgctg tctgactgag gctaaaaaag tccggctttt aaaagccgga 3201361 ctcccgtcta cccccgttca actctcttct aatcctgcaa gctgaccgca taatcccgcc 3201421 atacccggta caccggcaca aattccccgc cagcccttct tctatatctt tgtcagaagg 3201481 ttgaggggtt tcccgaaaca atgctttaag cgcaatgatc attcccggcg tacagtagcc 3201541 gcattggaag ccgccttctt ccaggaaagc ggtttgacac atatccagct cttctttttg 3201601 aagcccctcg atggttgtga tggaatggcc gtctgcttga taggccatcg tcatgcacgc 3201661 attggccagt tttccgtcga ttaaaataga gcaggctccg cagcggccga ttccgcagga 3201721 cacctttgtc ccggtcagct gaaattcctt tctaagcagg tcactcagat gtgtcgtagg 3201781 aacggcagca acctcccacg cctgaccatt cacggtcatc cggaactgtt ccttttttac 3201841 aggaaatggc ccggcctctt ttatgtccat tgcttcagcc cctttctgtc gatcgcttca 3201901 agcaactctt ctcttgaaat tggcagcttg tttatccagc atccgaccgc atcatgtact 3201961 gcctttacaa tcgccggagt gatggcgatt gttccgattt caccaacacc gcgcggtcca 3202021 tatacgtctc ccttcattaa gtcttctatt gcaatcagct tcatgtcagg aacatctttg 3202081 attccgggaa tcaaatagtg atcgagattt tccgcagcat aacggccatc cgtcattttc 3202141 gcttcctcca tcagtgtgta gccgagtgcc atggcagcgc cgccttcaat ttgacctcga 3202201 tatccctgcg gactgacaac cggacctgcc gcaatagcgt gctcacaatc tatcaatttg 3202261 acatcgcctg ttaacagatc tacctccacc tcaacggcag ccgctccaaa tgagtagagg 3202321 aaatggccgc ccaccacagg atcaggcgtt gttggaaagt caaaggccgt ttcctctgcc 3202381 aaagggcctt tttcagccag ctccttatac gtcaccacga gcgcctttgt gtttttgtca 3202441 cgcaagcctg cagcgccggg aataagattt tccgctgaac agccgctcca ttctgccgcc 3202501 cgttttttca actgagctag aaacggcttc ttcaaacgct ggatcgcgtg ccacaccatg 3202561 cttgtgccgc gggatgctgt ggaggagcct gacttcggca cttttgcggt atccccaata 3202621 acaatggaaa tatcctctgc ggcacaaccc agctcctcca tgacaatctg ttcaatcgct 3202681 gctagaatcc cctgtccgca ttcttcaaat ccaaacgaag cagtgatttt gccttcactc 3202741 gaaagagaca aacggcctcc tgccgcatcc attcggccaa accccagccc gccgccgtgc 3202801 attgtaattg ccgctcccgt gcctctttgc agatacccgc agttccggct tgttttttta 3202861 agaatgggag atttagatat ggcattcaac acctgtgccg ctccgtcagt tggtgcaatt 3202921 cgatgctcaa gcggccccaa gtcatgcggt tttctgatat tttttcttct cagctcgagc 3202981 gggtcgatgc caagcatgcc gctgagacga tcgagatggg tttcgagtgc aaatgtgatt 3203041 tggttgccgc caaagccccg aaattccccc gccaccccgt tgttcgtaaa tactgatatt 3203101 ccttcagtcc ggatattcgg aatacggtac ggccccgcgg catgctcgac agaaaaatca 3203161 agaacagccg gtccgagcgt agcgtaagcg cctgtgtccg ccacaatttt cacgtcgtgc 3203221 gccaatagat ttcccgaatg atctgcaccc gtttttatcg taatcttcat cggatggcgc 3203281 ttaatgccag aacgtacaga ttcctttcgt gtctgatgaa ttttgacagg gcgtccgctt 3203341 ttcagggcca aaagcgcagc atacggctga atattcagct catccttccc tccgaacgag 3203401 ccgcccatcg gacttgacac aattctgatc ttctcttcag gaatatcaaa aatacgggca 3203461 agctggaaac ggtctttata gccgtgctgg gttcctgcat acatcgtaaa acccccgtcg 3203521 tcttccggaa cggctacacc tccctccgtt tccatatacg tatgcatctg ccgcggcagc 3203581 tcataggttt cttcaaagac tgtgtcagat gcttgaaacc cttcttccac atcaccgttt 3203641 gaaaaaaatg cgcggtgcag gatattcccg tcctcatgca gtctttgcgc attcggccga 3203701 agcgcttttt ctggtgaatc catgacttcc agctctttat actcaacttg aatcagctcc 3203761 agcgccgctt ccgcgatttc ttccgtttcc gcagcaactg cggcgatcgc atccccgaca 3203821 taccgcaccc tgtcctcaca taaaaccggc tgatcaggga tgacaatgcc aaatcggttt 3203881 aagccgggaa cgtctttatg tgtgacgacg gcctgcacgc cttccatttt ctcagctttt 3203941 atggtgcaaa ccgacacaat ctctgcatga ggataagcac ttctcagcac cttgccatac 3204001 agcattcctg gaaagctgag atcggtcata tatttcaatt cccctgtgac cttacccctt 3204061 ccatccggcc tgactcttga cggtttgttg atgatcattt attcccctcc ctcagccatc 3204121 agctctgcca tgatgacgtt ggcagcggct ttttttctgt atgccgctga cataaaaaca 3204181 tctgaggaaa acggcagctc atggataagt gttttgtaca gctcatgcgg gtcccaccct 3204241 ggtgccatcc atttcgcttc gctgtccaat aatctcctag gagtgatatc ggcatggcca 3204301 gcggcgaggc gaatgctgcc gtctttcaaa aaacgtccag ctgcaacagc agccgctccg 3204361 gtaaaagcct ggcgccttcc aagcttgtga taaaatacac gctctccctc cgcccgcggg 3204421 atgatgacac gcgtgacgat agccgttcta aagtcttcct cactgagcca agcgccaagc 3204481 ggcagcctga ttagctcctt ttgatatacg ataagctcag caccaagcac aagcagaagc 3204541 ggaatgaaat caccgatttt actcgctatg ttgccgccaa tcgtggcacg gctgcgaatc 3204601 cccggtgcag cgacagcgga agcagcgtca ctgaaacagc taagcgctct cttaatcaaa 3204661 gggttctttc tgcattcatt cagtgatgtg agccccccga tcgacacgtg ggtgtcactg 3204721 gtgctgatcc ctcgcatttc gtcaatccct tcaaggctga caaggtgctg tttcggtaga 3204781 gttcctttgt cccactgaag ctgaaggagc gtgcttcccg atgcggcaca cacatccgga 3204841 gcaagcttct ctaaaagcga ataggcctca tcaagcgctg ccggtctcca taattgaata 3204901 ttcatccttg cttttgtcac ttggccgttc aagacatcgc cctccttacc atgtcatatt 3204961 cctcgggtgt atcaatatcg tccaactcac cgctatcctt tgcctccaaa accgctcctg 3205021 ctccaagctg tccgcttttc aggagcctgc gagccccttc atctcccttt aatcccttta 3205081 cataaggaaa acatgtcgac gagaagtaga ttggcggggt gaacgcccct aaaaacgatg 3205141 acacggcaaa tgactcagga gccagagcca caagggcatt gagatgatcg acggaaagct 3205201 gaggctggtc ggctaacaaa atgacaatgc cgtccgcccc catgctttct gcttttctca 3205261 ccccgctgct gactgaatgc ccctgaccct tttctgcgtc ttggcaaacg tgcaggctcc 3205321 agcgtttttg aaaaggcgga gcgtgatacg gcgctcctat ccactcaagg gaggcatgtt 3205381 ctgtccgctc gacgaccagc acgtgatcaa ggcgggacga cagagcagtt ttcaaggaaa 3205441 gtgagcctat gttttctcct tttagcggca aagccagctt gttttgtccc attcttctgc 3205501 ttttgccggc agcgagaaac acgccgatca gataggggct tctcatacaa ccgccacccg 3205561 ttttcttgtt tgaatgattt ctgcaactac acttaccgca atttcctcgg gaccttccgc 3205621 accgattttc agcccgaccg gactgtaaaa gtgagacgga ggatgttttc cgctcagcag 3205681 ccgtttcgtg cggtttgccg aacccaacag tccaatataa tggaggtttt gagaaaataa 3205741 gaagttgatg atcgtttgat cgtgctgata atgatgggtt gccacaacag ctgcatcatg 3205801 cggaaaaaat tgaaattcgc taagcatttg ttccggaaaa gcggtgatca gctgatccgc 3205861 ttttggaaaa agagaggatg tacaataagc gggccgccaa tccgtcacga taacagaaaa 3205921 ccctgtgtca gccgccaaat tggccagcgg tacattatcc ggtcccgccc caaacagaat 3205981 gagacgcggc ttcggttcaa ttcgctgaat aaacatgtta gtggtttgat cgaaatgcgg 3206041 taaatgaagc gttgaaacag tacgttgaat atcttgcaga ggcgcgtccg gccagttccc 3206101 aaaatgtccg ttctccgtca gaaataaata atgggaggat tcaatcttta taacggaagt 3206161 gacagctttg cctgaatgaa ggcagtccct cactttctca tagtgccgcc ttttttcctg 3206221 agtgattcgc tctgcatgaa catgaataat gccattgcac ccggctccca tgccccaaga 3206281 aagatcgtcc tccgaccgca tgtcgtaggg aatcagcgtt gatgtgagct gatcgcccag 3206341 cgcactgatt ctttggaata catcttcttc cacacacccg ccgctcagca agccaatccg 3206401 tctgcctttt ttcttaaaga gcatagaggc gcctgctttt cgatacgcgg agccttcaac 3206461 ttgaacaatt gtcgccagta cagcctcctc ctggtcttcc aggagcgcat ctaacatcgt 3206521 gtgaaaattc cccaatgccg catcctcctc tcgaaaattg ccgtgagaaa caactagttc 3206581 agcgtgattt tataggtaac ttgtataaag aatagacgat ggaagaaaaa atgactcatg 3206641 atttgtcaga aaatgaaaca catagaaaga ggatttgtaa aaagagtcaa acgaagaaaa 3206701 tcagattgga gaaaacacga aatcatatcg ttaaaaagct tgcggagttc cgcaagcttt 3206761 tctttacacc gctgcctggc ggccagcgtt ttcatacaca tccagcgctg cttggagcgc 3206821 ttttcctgct tcgattcctg cgttatgtct gagaagcaca gcctctaacc cggcaagcac 3206881 gaatagcacg ttttcttttc tgcagctgta ccccatcgtg ccgatcctcc agatcttccc 3206941 tgcaagcggg ccgaatgagc tggcgatttc aatgccgaat tgtgccagca gcatgtcacg 3207001 gacagactcg ccgtcaatgc cgccgggaat ttcgacacag gtgacaacag gcattttgca 3207061 gctgtcatct ccaaacaatc ttagccccat tgcctttatc cctgctgcta atgcggcttc 3207121 atggtgccga tgccgctcga aacgcgtctc aagaccttct tcaagcacca gtctgactcc 3207181 ctcacgtaag gcgtacagca tcgtcgtcgc ttctgtatga tgattgagcc gtctttcgct 3207241 ccaataatcc tcaagctggc tcaaatcaaa gtagttgctt gtaattggcc gatttcccga 3207301 aagtgctgcc ctgtcagctt gtgtcgcaat cccgcgttcc acctttttgc gagctgcaat 3207361 cacgtccgcc acccgctcat tatatgtaat cggcgccatt cctgaaggca cagacaaaca 3207421 tttttgcgtt ccgccgatgg cagcgtcaat cttccattca tcgactttaa cctcgcagcc 3207481 cccaatcgtt gcgactgcat cgacgataaa caatgcatcc tcggtgcggc aggcttcgcc 3207541 gatggctttc agcgggtgaa tccgtcctgt cgatgtttct ccatgcacca tggccacaat 3207601 tttcggcttc acttttttta tctcccgtat gatgtcctcc gggtcaaaaa ccgttcccca 3207661 ttcgcactcc agcatatgaa catttgcccc atatcgctcg gcgatttcag tcagcaaata 3207721 accgaaacgg ccgtaaatgg gaatgagcac atcatcttcc ggctctatca cactagccag 3207781 cactgcttca attcccgccc gtgaagtgcc gtcaatcggg tatgcccagc ggttttttgt 3207841 ttggaacagc tcccgaagca tctccatcgt ttcattcata atacctgtaa acgccggatc 3207901 aaattggccg acaaccgggg tgctcattac tcttaataca cgcggatcaa cctcaacagg 3207961 ccccggtgtc ataatcgttc ttaacggggt gcataattct cttctgcctg acacagccat 3208021 tcctccttta tcagtaagcc agtttgtata ataaatcagt cagtgcgcgg acgccgatct 3208081 caagctgtct ggctgacgta tattccttcg gtgagtggct gacgccgcct cggctcggca 3208141 caaacagcat acaagcagga tagcgccttc cgatcatttg cgcgtcatgc cctgctccgc 3208201 tcaccatttc ctcacagctg aagccgtttt ctaatgctgt ttcaaaagcc gcagccttca 3208261 gcctttcgtc catcggcaca ggctctatcc gcatatattc atcaatcaca gcgcgaattc 3208321 ctttttgtag gcaaatgccg ttgatcaaag caaccatgtc ttgatgaaac tgttccagca 3208381 catgctgatg ctgatggcga atatcgattg aaaactggac gcggcccggt atgacattgg 3208441 ctacattggg ctctgccgtt atttttccgc atgtcagacg gagctcatcc ggcagctcat 3208501 ccgaccgcag cagcagctca tgaatgatac ggctgctggc tgcgagcggg tccttgcgcc 3208561 atttcatgga ggtggttcct gcgtgattgc attctccttc gagcgtgacg agatatcgtc 3208621 tctgccccgc aatacttgtc acgatgccga gatcccggcc tgacatttcc aacgtcttcc 3208681 cctgttcaat atgcagctca acaaacgcgc tgatatctgt cctatatgct gactgaaaca 3208741 cacctttgcc aaaaccgctc tcatgcatcg ctgtttggag ggagactccc gactcgtctc 3208801 ttggctcttt tgcatcttgt tctgaaaaaa cacccgtcat attccccgac ccccaatagg 3208861 tcattggaaa acggctgcct tcctcctcac ataaggagac cgcctcgagc gttttttttg 3208921 gcgctccgta tgtttccttg agctgcttta acgcgagcat tgccgccaga acgccatagg 3208981 cgccgtcgta ttttcctcca ttgatgacag tatcgatatg tgaaccggtt acaatgactt 3209041 catccggaga ctgggtgccc gaaagccttc caaacacatt gccgacatcg tcgaatcttg 3209101 tttcaagccc gaaagaagac atttccgttt tcacagcaag ctgtgcgtcc atccactctt 3209161 ttgtgtataa aagcctcgtt acgccgccat ccgcagacgc accgtattgg gcgagccatt 3209221 caatataatc tgtgatgctg ttttttactg aaagcttctg cttttccatg tactcccccc 3209281 tctggccgct atggtgactt cattatagaa ggagcaacat gatagttcat tgacagatta 3209341 accaaaaaaa cgtttatttt ttagccacag tatccatcca gcaaccagat acaccctaca 3209401 tgtcacaact attttgatgt aaaggtcaaa agaaaacacg gtaaggaaga gagccagcaa 3209461 gagcgaaaga gagggtcaaa atgcctttca tatgaacaag ctaagctgga gaggcgatgt 3209521 tcgcggaacg gatgaaaaca gaaatgccgg cagcccgcaa aaacaggacc taaagatatg 3209581 gaaacaggag atttccgcct cctccaaagg gactaattta caattttaat gaaaaatata 3209641 caaaatgaca cttctatcct ttatttcaat tttagataat agatatgatc tgataaaagg 3209701 agggcaagtg atgacaaaaa aagcatggtt tctgccgctc gtctgtgtat tactgatttc 3209761 cggatggctt gcgccagcag cttcagcaag cgcgcaaacc acattaagcc ttaatgaccg 3209821 attggcgtct tccccttcag gaacgggaag ccttctctca ttagccgccc ccgctgcacc 3209881 ctatgctgac acagatacct attatgaagg ggctgaaggt aaaacaggag actcgctaaa 3209941 aagcaccctg caccgtatta tcagcggaca cacgatgctg tcctacagcg aagtgtggaa 3210001 cgcgctgaaa gaaacggatg aagacccaag aaatccgaat aacgtcatcc tgctctatac 3210061 gaatgaatcg cgttccaaaa acctgaacgg cggcaatgtc ggcgattgga accgcgagca 3210121 tgtctgggcg aaatcccatg gcgattttgg tacgagcaag ggacctggta ctgatattca 3210181 tcatttgcgc ccggctgatg ttcaagttaa cagcgccaga ggaaatatgg attttgacaa 3210241 tggcggcact gaatatgcga aggcacccgg aaattattat gacggcgatt catgggagcc 3210301 ccgcgatgat gtgaaaggcg atgttgcccg catgctgttt tacatggctg tccgttacga 3210361 gggtgatgac ggctatcctg atcttgagct taatgataag acaggcaacg gctcagctcc 3210421 ttatcatggc aaacaatctg tcctgctcga atggaataag caggatccgg ttgacgaccg 3210481 cgagcggaaa agaaatgaaa tcatttatga aaaatatcag cacaaccgca atccatttat 3210541 cgaccaccct gaatgggcgg atgagatttg gccgtaagaa aaaggtgctc cttttgagga 3210601 gcaccttttt ctaatacaca gcctcttccg tttccgcatc gaaaaagacg acgtggtcca 3210661 ttttcactga gagctggatt gaatcgcctg catcgattcg cgtgtttccg tccaggcgga 3210721 ccttgagccg ctcgtcccca gccatgacat gcactatgag ctccgagccc agattttcat 3210781 tcacttccac gttcgcttga aacactgaat caaacaactg gtcatttcct gtcatttgtg 3210841 tgatgtgctc cggccgtaca ccggcaatca tctgttctcc ggcatatccc ttttccttca 3210901 gccgctttgc tttttcttca ggaatatgaa gccggatcga agaatttgtg aaaaacagct 3210961 cgccatgctg ctgttctatg atgcctttca aaaagttcat tccgggagag ccaatgaagc 3211021 ctgcgacaaa caaattggcc gggtaatgat aaatgtcatg aggtttcgcc acttgctgaa 3211081 tttccccttc attcatgacg acaatccgat ctcccattgt cattgcttcg gtctggtcat 3211141 gcgtgacata aatgatcgtt gcctctaatc gctggtgcag cttgctgatt tctgtccgca 3211201 tcgtcactct tagttttgca tccagattag aaagcggctc gtccattaaa aagaccttcg 3211261 gctccctcac aatcgacctg ccaagcgcca ccctttgccg ctgcccgccg gagagcgcct 3211321 tcggttttct cttcagcaaa tgttcaattt ctaaaattct ggctgccgca tgaacccgct 3211381 cggcaatttc ctgtttcgcc atctttctga gctttaatcc aaacgccata ttatcaaaaa 3211441 ccgtcatatg cggataaagc gcatagttct ggaataccat cgcaatatca cgttctttcg 3211501 gcggaagatc attgacccgc tccccatcaa taagaagatt tccttcagaa atgctttcta 3211561 atccagccac catccgcagc gttgttgatt ttccgcatcc tgacggcccc accagcacca 3211621 aaagctcctt atcctttaca tctaaatcaa agtccttcac ggttaattgt gagtgatatg 3211681 attttttgac gtgttcaaat gttaatgaag ccatcagaaa agtcccccta tcttttgacc 3211741 cgttatttcg tcactggaaa caacttggtc tttctgttat ttttagagta atcgattccc 3211801 atttttgcta tatttctaaa ataaaaaatg taaatttgta ttataacgtc ataatacatt 3211861 ataatataaa taataggtta aaaggaggct accctttgtt aaacaacgga agttctacac 3211921 ctttatacat tcagctaaaa caaatcatca ctgatgacat caaaaagggc gtgtattccc 3211981 caaccgccaa gctgcctacc gaaaacgagc tttgcaccaa gtataacgtc agccgcatca 3212041 ccgtcaggaa agccattctc gatttagtcg aagaaggcta tctgatcagg cagcagggaa 3212101 agggaacgtt cgttaaaagc cctaaattaa aacgagagct gatcgctgta aacggctact 3212161 cggaatttat ggaatcaacc ggcaaaaaac cgaagcatca tgtgctgtcc catgacatca 3212221 ttccagcgtc aaaacccatc gccgaaaagc ttcaaatcca acccgagagc cctgtggttg 3212281 aattaaaacg gattttatat aatgatgatc agcctctcac ctttgaagtg acgcattatc 3212341 cgcttgattt gtttcccggc attgatacct ttattgctga cggcgtctcc atgcatgata 3212401 ttttgaaaca gcaatacaaa gttgtaccca cgcacaatac gaagctatta aacgttgtat 3212461 atgcccaaca ggaggaaagc aaatacctgg attgtgatat cggggatgcg ctgtttgaaa 3212521 ttgataaaac ggcttttaca tcaaacgacc agccaatcta ttgctcattg tttttgatgc 3212581 acacaaaccg tgtcactttt accatcaaca gcccctacac ataacaggca taaaaaacga 3212641 gacactgctt atagtattct cgttttttca ctgcttcccc cgtcctccaa gcgataagga 3212701 tagccatagc cgaaagctcc gtacacaccg caagttttcg cagccgtttc agcagcctgg 3212761 cgcaaagcat acgttatatc ctgcttcacg caaaaggcag tcaaaaagcc tgctataaaa 3212821 gaatctcccg ctccaagtgt atctattata tcagcttcca caatcggctg atgatagact 3212881 cgatcacccg cagacaggat tgctccttgg ccccctcggg tcatacaaac cattttggct 3212941 ccgtacccat gagctgtttt ggcaagctca ccgcattccg actcactcaa atcgcttcct 3213001 gaaaaaaacg catacgtcac ataaggacag accctcctca aataatcatc ctcccgattg 3213061 gttgaaaaat caaatgagac cgggaccagc ccgcacagct gcggaagatc gttctcaagc 3213121 ctgctgtaca cgctcgtatg cagcagatca tgcccgctga taaaagatac atctttctcc 3213181 tgaaacgcga ggcgaagccg ggactgaatg ccgcctttat ttgatctgac aaaaatgcgg 3213241 tccccctgtt catcaagggt gacaatcgcc atcccgtttt ctccgtgcgc ctggcggata 3213301 taatctgcat tgacctgctc cagcttgaga acgttcaaca gatgcgccgc ggcttcgtca 3213361 ttgccgacga ttccgatata ggaagactca tgcccgagcc gcttggcaag cacagcaacg 3213421 tttaaggcat ttcctcccgg gtaaaatgtt tcttgatcct ggtagtaatc tacaacatta 3213481 tctccaaccg caatcaattt catagcgctt cctcctttat ccttttacac tgccgcttgc 3213541 aatcccgcgg acaaaatatt tctgcatcaa taaaaataga ataataatcg gcgcggctga 3213601 aatcgttaac cccgccagca ggacgcccca gtctgtctgc agcgcgtctc tgaactgcat 3213661 cagcccggct ggaatggtcc gtaaattctc atcatctatg aaaataatcg caaacataaa 3213721 ctcattccat gtatggtaag ccgtcaaaat gccggatgtc accaaaatcg gcacgctcat 3213781 tggtaagaaa attctgaaaa atactccaaa acttgtacac ccatccaaat aggccgcctc 3213841 ctccaattct tttgaaatag aaagaaaata agagcggatc aaaatgatgg tgaatgggat 3213901 ccgataagcc gcatacggca agattaacgc ccaatacgta ttgtacaggc ccagcgactg 3213961 aataatagaa taaagcggca caagactgac ctgcggcgtc agcatcaatc cgccaagaca 3214021 tagcaccaaa aagaatcctt ttcctttaaa ctcaaaccgg gaaaggccat acgctgccca 3214081 tgcactgata aagacagtga tcacacacgt cagcgccgta acgatgacac tgttcataaa 3214141 ataagaagaa atcccctgat tccaggcgga aacaaaattt tccggatgcc acgaagacgg 3214201 cagcgaccag ctgtgctcaa aaatatcgtc agagttttta aaggcgctca tcaccatcca 3214261 gagaagcgga taggcaatcg caatcagata aagaaacaga aaaacccaca cagacgtttc 3214321 tccgatatac cattttcgtc taggcttatc tttcacctca atgtgctggt caggcaccgg 3214381 ctccaatctg aacgaatctg tcttcttctg aggcagcatc agttactcct cctttccggt 3214441 tttaaagaac ttcatttgca tgagcgataa tgcaagcgta atgattaaca cgacagtggc 3214501 aatcgctgag gcgtagccca tcatatcctt tgtaaaggcg cttttatata aaaacgtgct 3214561 caagacttct gacgcttttc ccggcccgcc gcctgtcaaa atgtacggct cattaaagac 3214621 cgtaaaggct ccggtcagcg tcatgaccac cgcaacaaaa gacatctctt tcgtctgggg 3214681 aacagtaata tgaaaaaact gctgaatttt acccgcgccg tcaagccggg ccgcttcata 3214741 cagttcatcc ggtatttttt gaatcgacac gatgtacagc atcgcaatat aaccgacaga 3214801 ttgccactgg gacacaaaaa tgacagaaag catagctgtg ctgtcatccc cgagccaggc 3214861 cctcgtcagc tgatcaagac cgatggcctg aagcagctga ttcaaaagcc ctgtctccgg 3214921 attgtaaata aaatcaaaca aaagcgcgat caccgtcatt gagatgacaa ccggcaaaaa 3214981 gaaaacggta cgaaaaaacg gcgaccattt tctgaccagc ttatcctcaa gcaccgccgc 3215041 caaaatcaaa ccgccaaata cctggcatac aattgagatc actgcataaa gcacattatt 3215101 ggtaagtgcc tgatagaaga caggatcatg aaataattca acatagtttt ttaagccgat 3215161 aaacgttttt tccggagaaa atgagctcca ctgaaacagg ctgaggaata cattctcaaa 3215221 aatcgggata taaacgaaaa gtaaaaaaac gagagcgggc accaaaaaca aataggggat 3215281 tattttattc tgattgacca agggtatctc atctccttta taaaaagaaa aggtgcgaag 3215341 cttcaccttt tctttgattt attcagctga cgccctcacc tgctttgctg ccttttgaac 3215401 ggctttcatc acctgctgcg gtgtcatgtc gccgccaagc atttgctgga cgcccgttag 3215461 gtacgcatct gcgacttcaa catcgacatc catatcaaac catggaacca ttgatttggc 3215521 atcaacaata tgctgaacgg cttcacgctg aatggctgtt gcattttctt cagtagccgt 3215581 accttgcact gcactgtatt tcccgacatc tttcacgagc ttttcgccca ttcttttcga 3215641 cgtcaagaac tgcaaaaatt ccatcgcttc cttcggatgt tttgttcttg aggagatcat 3215701 gaatccttcc ggcgctcccg ttaacgcttc tgaagatcct ttctgcccgc tgatttcagg 3215761 aaatgggaac atcccgagat taaccggttc aaccagcttg atttccgctg tttccgcata 3215821 tatcatcgcc gactttccgc tcttaaattg ctgtctcaca tattcgtggt cgacggagtt 3215881 tacatgttta ttaaagtaag gcatcagctc ttgaagcttt tcaagtgctt ttacgtagcc 3215941 ttcatcagta aattcacccg ttttggcgtt atagtccttt tcccgtgttt tttcatcgac 3216001 catccgctga ttaagcgtgc cgatatagtg cgagattgtc caagtcgcct ttgttccaaa 3216061 gctgatcggt gtgtagccat gttctttcag cttttttgac acatcgatta attcatccca 3216121 cgtcttcggg ggatcaagat tcagcttttg gaaaatgtct ttattataga agaatgattt 3216181 agcgtccatt tgccacggta cgccatattg cttgttttca taagtaaatg gtgtaatttg 3216241 cgattgaacg agctgtgatg accaatcggt gtcatttttg tagtaggacg agagatcaag 3216301 tgctttattg cctctgataa atttaaaagc aaactcatcg ctccaagaga agtaaatgtc 3216361 aggagggctg gtggttccca gcatgacctt aattttatct ttataggagt catttaaaac 3216421 ggcttcaatt tgaatgtcga tatctgggtg atctttttca aattccttaa caacctcttc 3216481 aaaataactt ttttccggct cctttggcca tctgtggaaa aatttcaatg tcacctttcc 3216541 gtccgctgaa ctgctttggc tcgaacagcc tgcgatggtg agcatactga cagctgcaat 3216601 gatcaagaac aacaacattt tcttcaaagg gttggcctcc tctggacatt agactataat 3216661 gttatataac attatagtct aatgcataat ggttcttcat tttcagatca atactcaact 3216721 ttccacatgt atcttctatg agataaagga tgatttctct cctctgccag ctcgtctgca 3216781 tagcttctca gcacacgatt gagaacgagc ggagcaagat agcctttaac tgaatcgtca 3216841 attgcagtga agtcgtaaga tgcagcatca agcacagtga gctttttgcc atactttttc 3216901 gagaaggtaa gcgcccgctc ttcaagaggt cttgtttcat ctaaaccgag caggatgata 3216961 aacggcacgg attcatcaat aatttcaaac ggtccgtgaa aatattctcc ggcatgaatg 3217021 gcgtgggaat gaatccattg catttccatg agaatgcaga tgctgtagga gtaagcgaca 3217081 ccgtagtttg caccgcttgc catggtataa ataatgcttt ctttttcatg ggcttttgca 3217141 aattgcttgg cgttgtcagc ttcctgctta agggcttttt catatacagc ctgcaattga 3217201 tctaagcctt caattgcttg ctcaaatttc gtattgtttt ctaatacttg cagggttcca 3217261 aaaacgattt gatacaaaac gccatagttt gtattgatcg caagcgcctc atcaccccaa 3217321 tcgtactggg caacatattg cgcttcctgc gctaaaggag actccggttt aaacgtcatc 3217381 gcaatcgtaa gtgcgccctt gccccttgca aacgcagcag ctttgactgt ctccggggta 3217441 tttcccgaat gcgagcacaa aataacaaga gacttttcac caagctgaac agggttgcgc 3217501 tgaataaatt cgttggcgct gtagagatcg gagtttattg attttgactc tctgtcaaac 3217561 acatacttac tcggatacat aatggcagaa gaccctccgc atgcgacaaa gaatacatga 3217621 tcaatggttt tccctttcaa atcctgcaag aaagcttgaa cctcacgatt tacttttgct 3217681 gtggcctgac tcaaatcctt cactcctcgt ttttattata taacgttata taacattata 3217741 tattgttata ttaaagtccg cgggtaggat tgtcaatatt attttctgaa atttctcaat 3217801 aatttattcg gatgacagac aaagggtcta tatgcgaaaa aatgcccaaa tcaaaagcca 3217861 gaacttgact taagctctgg cttcgctgtt caatccgcag actgacgtct tatttaaaaa 3217921 ataccttgtc tatattgtac ttcgagtgct gtgtattgat gatatatgtt tcgtaaatct 3217981 ctctttccat tggatcatca actacacata cctcaatttt ataaacttca tctctgtgat 3218041 gtttgatcgg tgaaacagtg tcttcgaaat gcttcttaat tctctgtctt aactttctgg 3218101 ctttaccgac aaacagcagc tcgtcatgaa tgttgtaaaa cataaaaatg ccgcctttgt 3218161 cccttgggat ctggtgaaag tcgatgaatc cgtgaatcgg ttttatcttc ggctcgttat 3218221 cattagctga ctgctgtcgt tcagtgatgg tgacattcgg tgcgggtata tcaattttta 3218281 tcaaaatcag ttcacgtcct ctttttcatt aaagataaat gctaacacat acagaaaaga 3218341 aaagctagaa cagctttatt atatttgttt gtcatgctct tacttattat gcaagtgctc 3218401 cggctggatc ataaggacta aggtctaatt ctgtctgctt tccgagaact agctttgcga 3218461 gctctgcacc caaaaacggc cccatcgtca gtccagaagc acccaaaccg tttgcagcgt 3218521 acaggccttg aacattcggc acggccccta cgaccggcag aaatcccggt gtaaacggcc 3218581 tgaagcccac tcttgtttca acagcagccg catcagcaag acccggtgca acggctaacg 3218641 ctttgctcaa tacttcgtgc tggcctccgg ctgtcacacg aagatcatca agaccggcat 3218701 cgttttcgtg tgtggcgccg gctacaattc tgccgttatc aaacgacaga atgtactgat 3218761 cactcggcgg cattacaacc ggccacgatc ctgtatctgc atctgtcatt tcaaaatgca 3218821 taatctgcgc tttttgaaat gacacttgaa aatgaatgcc aagaggcttc aatatctcat 3218881 tggcccatgc tcccgccgtc acaatgaccg cgtcagccgc aaactgcttt gtatctgttt 3218941 gcacgccggt gactgttccg ttttcaaaaa gcaaggacgc atttcctttg atgaccgttg 3219001 cgccgcgttt ctctgcagcg cttaaaagcg accggcacag cgctcttccg ttcacacggg 3219061 cggcaccgct gatatgaacc gattcatagc cgtcagctaa aatcggaaac agctttttcg 3219121 tttcacttgc agacaagcgg gtaatgtcgc cgatttccgg cgcatcctcc cgtctcttat 3219181 acgccctttc ctccatttta tcgagtttag acgcgtcagt atgaatgctg atggcaccga 3219241 cacgtttgta tcctgtatcc gattcaccgt ctttttccaa ttgatggatt aaatccttat 3219301 agtaccgcgc tcccccctta gcaagctggt accaatcctg attacggcgc tgcgagagcc 3219361 aaggacagac gatccccgcc gccgcatcag tcgcttgtcc cggctctttc cgatcaatga 3219421 cagtaacgcg agcgcctgtt tttgcgagat gataagccgt cgacgcgccc agaatccctg 3219481 cgccgacgat gatgtacgat ttcatatgca aacacctttt ctattataat gtctattcat 3219541 tttaccaaat caaatgcttt ccttcgacct tttgccctaa tgtggaaaaa ccgcgaagtt 3219601 cgtccaatct ctttactctc ctatcgaata tcctgtcact atcaatagag aaaggatgat 3219661 accatgagcg aaaatcgtca tgaaaatgaa gaaaacagac gcgatgcggc agtggcaaaa 3219721 gtccaaaaca gcggtaatgc aaaagtcgtg gtcagcgtga acacagatca ggatcaggca 3219781 caggcgcagt cacaagacgg agaagactaa tgaacgaaaa catcattcct cttaacagac 3219841 atactcaaga gatacccact actgaatctg ttatcaaaaa cagcggcaac tcagaggtcc 3219901 atatcgacat tcacattgat acaatgccaa ttgcttttgc tatattatgc tctgcattag 3219961 ccgcaaagca gatgacaaaa gaggaattcg atatggctta tactcaattg cgagagatga 3220021 acagagaaaa taacagcaga tcatctgtaa agcaaattat caatcaagag acagaagaag 3220081 agtaaaaaac cgcggcccct cggccagcgg tttttcttct gcatacaaaa aggacgcgac 3220141 tgaatcggtt acttctgtac aatttgaata aggttaccgc atgtatcgtc gaagacagct 3220201 attgtgactt cgcccatttt tgtcggttcc gtcgtaaacg tcacgccttt ttcctttaat 3220261 cggttgtact ctttttgaat atctgcaacg ccaaacattg tggccgggag gccttcggag 3220321 aatatcttct tttgatactc cttggcggca ggatgttcat tcggttcgag taaaagctcg 3220381 gttccgtctt gatcatctgg agaaacaagc gttatccacc tgaatttccc catgggaacg 3220441 tcttcctttt ttataaaccc aagtttttct gtataaaact ccagtgccat gtcttgatct 3220501 tgtacaaata tactggtaac aacgattttc atactgtttt tccctccttc gatatgaatg 3220561 aagcatggta ctatgctaac aatctggcta caagcaaaac aacccacaca tttatcagag 3220621 gccctgttct gattttataa aattattcta tccatccttt cagcaaattt ttaagcggtt 3220681 cgttgttgaa tataagtact cgatattttc cctttcgttt tgatgttacg agtcctgcat 3220741 cctccagtac agaaaggtgt ttagctatcg cctgtcgcgt aatagaaagg tcgtactttg 3220801 taataagacg tatcgtaagt tcatacaacg tcagctcgtt gcgttcagat aattcgtcta 3220861 atataagccg ccgagtcgaa tcgccgagtg ctttgaatat agcgtctttg ttcccattca 3220921 tatattgagt ataagcaacc cattagttgc atgtcaagta taagcaactg tatggttgcg 3220981 tgatatagaa actgaaccta tccggcgcag gtctgaaata ttctaatcga taaggaatta 3221041 aaaccattaa aataacagtg gatatgtctc tgaaaaataa aagaagacga acttcaaaag 3221101 ttcgtcttct acaatcaaat tcggcacgcc ggccatttta aagttgataa ctatctctaa 3221161 accccttgat aaacaaagga gttttcatca ttaaccgata gaaccttcca tttcgaactt 3221221 aatcaaacgg ttcatttcaa ctgcgtattc catcggaagc tcttttgtga atggctcgat 3221281 aaagcccatt acgatcattt cagttgcttc ttcttcagaa ataccgcggc tcatcaagta 3221341 gaagagctgc tcttcagata ctttagacac tttcgcttcg tgctccaatg aaatgttatc 3221401 atttaagatt tcattgtaag gaattgtgtc agaagttgat ttgttatcca taatgagcgt 3221461 atcacactcg atgttagagc gggcgccttc cgctttgcgt ccgaagtgga cgattccgcg 3221521 gtacgttact tttccgccct gttttgaaat cgattttgat acgattgtag atgatgtgtt 3221581 tggtgcaagg tgaatcattt tcgcacctgc atcctgatgc tggcctttac ccgcaagagc 3221641 gatagaaagc gtcataccgc gcgcgccttc gccttttagg atacaagccg gatatttcat 3221701 tgtcagctta gaaccgatgt tgccgtcgat ccattccatt gttgcgtttt cttcacagac 3221761 tgtacgcttt gttacaaggt tgtaaacgtt gttcgcccag ttttggatcg ttgtataacg 3221821 gcagtagccg ccttttttca cgatgatctc aacgaccgca ctgtgaagtg agtttgttgt 3221881 gtaaacaggc gcagtacagc cttcaacata atgaacgctt gcttcttcgt caacaatgat 3221941 cagtgtacgt tcgaactgac ccatgttctc agagttgata cggaagtaag cttgtagcgg 3222001 tgtttcaacc ttcacgcctt taggcacgta gatgaaagaa ccgccggacc aaacagctga 3222061 gttaagcgcc gcaaacttgt tatcagtcgg cgggattact tttgcccagt gctcacggaa 3222121 aatatcttca ttctctttca gcgcgctgtc agtgtcttta aagacgatgc cttgtgcttc 3222181 aagatcttct ttcatgttgt ggtatacaac ctcagattcg tactgagcag aaacacccgc 3222241 aaggtatttt tgttcagctt caggaatacc gagcttgtcg aatgtttgtt taatttcttc 3222301 aggaacttca tcccaagaac gctctgaacg ctcagacggt tttacgtagt acgtaatttc 3222361 gtcaaagttc agtgagttta aatctccgcc ccattgaggc atcggcatat tgtagaaatg 3222421 ctcaagtgat ttcaagcgga agtcaagcat ccattgaggc tcttctttca tgcgagaaat 3222481 ttcttctacg atttcttttg tcaatccgcg ctctgaacgg aaaatggaaa cgtccttgtc 3222541 gtgaaaacca tacttgtatt caccaatatc aggcattttt ttagccatcc attttcactc 3222601 caatcctttt aattgccgcc ttcttctttc gcgactcctt tttcaagtgc tttccatgac 3222661 agggttgcac atttgatacg ggcagggaat tttgaaacgc cttgaagggc ttcaatatcc 3222721 ccgagatcta tagaatcatc atactctttc ccttgcatca tatccgagaa aatcttagac 3222781 atggaaaggg cagtttcaat atctttccct ttaatcgcct gagtcatcat cgaagcggat 3222841 gccattgaaa tggaacagcc ttccccttca aacttcgcat cttccacgat gtctccgtca 3222901 agcttcattg tcagtctgat gcggtcgccg catgtcggat tgttcatatc cacgacaatg 3222961 ctgtcattta aaaccccttt atttcgcggg tttttgtaat gatccataat cacctgtctg 3223021 tacaatgtat ctaagtttgc attaaaagac atttgtaaaa tactcctttg tcttttgaag 3223081 agcttccaca agcttatcaa tctcttcctc tgtattatac agataaaagc ttgctcttgc 3223141 agtagcagtt acatccagcc atttcatcag cggctgcgca caatggtggc cggctctgac 3223201 tgcgattccc tccgcatcaa gcacagtcgc cacatcgtgc ggatgaacat catcaaggtt 3223261 aaatgtgaca agcccggcac gctcttccgg cccgtaaacc gttacgccgt caagctggcg 3223321 gaagcgttca agcgcataag ctgcaagctt gtgctcatgg cgggaaatct catcaagacc 3223381 gatttcttcg agaaaatcaa tggcggcacc gaggccgatt gctcctgcaa taatcggcgt 3223441 acccgcttcg aatttccacg gaagctcttt ccaagttgat tcataaagcc cgacaaagtc 3223501 gatcatttca ccgccgaatt cggcaggctc catgttttcc agcagggctt tctttccgta 3223561 cagcacacca acaccggtag gtccgcacat tttatgggaa gaaagcgcaa agaagtcgca 3223621 atcgagatcc tgcacgtcaa ttttcatgtg aggcgtgctt tgtgcaccgt ccaccacaat 3223681 gacagcccca ttgtcatgag cgattttcgc catttcttta atcgggttga ccgtgccgag 3223741 aacattagat acatgagaca ccgcaacaat ttttgtgttg cttgtgaccg tttctctgac 3223801 gtcttctaaa gaaatcgttc cgtcttcctg caacggaata tattttaatg tggcgccagt 3223861 tgcttttaca gcctgctgcc acggaatgat attcgcatga tgctccatgt aggtgatgac 3223921 cacttcatca ccaggtttca ggttggcgcg cgcatagctt aacgccacca tattcagtga 3223981 tgtggtcgtg ccttttgtga aaataatctc agccattgac ttcgcgttaa taaacttgcg 3224041 gactttttca cgcgctcctt cataaccatc tgtcgctctg gttccaagtg tatggacgcc 3224101 ccggtgaaca ttggaattgt attggttata atacttatcc agtgtttcaa tgacagcacg 3224161 cggcttctgg gaagtcgccg cgctgtcgag ataaacgaga tcatgtccgt tcacttgctg 3224221 atgaaggatc gggaactgtt cacgaatatc tgtgatattc attacttcac tttcctttcg 3224281 ataacagaaa ctaattgttt cttaacgcct tcaatcggaa gttcatttac taccggtgca 3224341 aggaatccgt aaatgactaa gcgttctgct tcttctttcg gaattccgcg gctcatcagg 3224401 tagtaaagct gaatagggtc cacacggccg acagatgccg catgtcctgc agttacatcg 3224461 tcttcgtcaa ttaaaagaat agggtttgcg tctccgcgtg ctttttcgct aagcatcagc 3224521 acgcgtgatt cttgctccgc attcgcttta gaagcgccat gttcgatttt gccgattccg 3224581 ttaaagatag aagaagcgga atccttcatc acaccgtgct tcaagatata gccttcagaa 3224641 gctttaccga aatggatgat ttgtgttgtg aagttttctg tttgctctcc tcttccgaca 3224701 acaaccgttt tcgtatcgcc gtatgtgccg tcaccgtaaa ggtttgttgt gttttcggaa 3224761 atcgtgtcgc catcgttcat caggccgaga gcccactcga ttttgctgtc gcgtccgcgc 3224821 gcagcaccgc ggcggttcac ataagttgtc acaccgcttg acagattatc caccgcaccg 3224881 tatgtcacgc tggcattatc acctgtgatg acctcactga taatattgaa gacagcgtct 3224941 ttcgggttta cagtgctgat gtagttttct acatatgtta cagagctgtg gtcttcagcc 3225001 acaatcagca cgtggttgaa tagagctgta tcattgcttt cgtggacata aacagcctga 3225061 accggcgtct ccacctgaac atttttcgga acataaagga atgctcctcc gttaacaaga 3225121 gccgcgtgaa gtgcagttaa cttatgttcg tcaaccttca cgccgtcctt cataaagtat 3225181 ttctccacca agtcgctgtg ctcgcgtgca gcagtcagaa tatcagtgaa gatgacgcct 3225241 ttgtctttca attcttgaga aagagaaaga tgtgccggcg tctggtcacg ctgtacgtat 3225301 aatgttttat cttcgttttc aatgtcgatc agcgctttta cttcatcagt caaatcttct 3225361 aatgaagaaa gcggttcgtt atccactgta tgcttcgcga aattcgtgaa gttccagttt 3225421 gtgatttttg ttttgtcagg tttcggcatc ggcagatcct cagcttgttc aagagcctgt 3225481 aagcgcaggt tcttcagcca ggcaggttct tggtgctttt cggaaaagct tttgagatac 3225541 tcctgatcta cggatagttt tgtacctagt gtcatattaa tccccctaac gcttacgctt 3225601 cttggccaac agtttcgtct tcaatgccaa gttcttgttt gatccagtca taaccttctg 3225661 cttcaagacg ctgtgcaagc tctgcaccgc cggattttac aacgcggcct tgcatcataa 3225721 cgtgaacaac atccggagtg atgtagttta acaggcgctg atagtgagtg atcatcaggc 3225781 agccgaagtt ttcgctgcgc attttgttga tcccttttga tacaactttc aaagcgtcaa 3225841 tatcaaggcc tgagtcaatt tcatcaagga tggcgatttt cggttcaatc atcattaatt 3225901 gaaggatttc gttgcgtttt ttctccccgc ctgagaagcc ttcgttaaga tagcgctgag 3225961 ccatttcagg gtccatttca aggaactcca tgttttcgtc cattttgcgg atgaatttca 3226021 tgagagaaat ttcatcgcct tcttctctgc gcgcgttgat tgctgagcga aggaagtcgg 3226081 catttgtcac accgctgatt tcacttgggt actgcattgc aaggaataag cctgcctgcg 3226141 cacgctcgtc cacttccatc tccagtacat ctttgccgtc aagcgtgatg ctgccttttg 3226201 ttacttcata tttaggatgc cccataatag cagctgataa agtggattta ccagttccgt 3226261 tcgggcccat tactgcgtgg aattctccac cttttatttc aaggtttaca ccctttaaga 3226321 tctctttccc ttcgatttca acgtgaagat ctttgatcgt taatgttgaa gcagccatat 3226381 ctatacctcc aaaaatatat aatcattatt ctcattttat tctcattcta attttataac 3226441 aaatgaaaag taaatacaac tttttatcgt gccttgcaca ttcctcaagt ttaacaaaga 3226501 tcagcacttt attaaagcga ttgaaaaaga aaaagagtgg attcccaccc ttttttaaaa 3226561 gattgatttt ctcaataagc tcccgcagaa atccgcttgc ttttttcata atcaagctct 3226621 ctctgccgct ctactttcat tcttgtttcc agccggcgtc catattcctc gtatccaatt 3226681 ccgtgtgaca gctgcatcgc tttttccatt tctgacgtat aatcgaggtt cagtctgtcc 3226741 tggctgctgc aaataatgaa tcaatccctt catatatttg ctttttattg taccagtgct 3226801 gcgttggatg ccgcaaaaac gatttggcgt gaaatagcgg cagatgagac gaaagcatcc 3226861 tttcagaaca aatgagaatg gtttttcgga atattccttc tcttaatgcg tggtgtttcc 3226921 gaattcctca atgcactgtt gaacgactgt cacgccttgg ctgaaagctg cgccgcctcc 3226981 aaatgccgct gccacactga cggcttcgag aatgttttct tctgacgctc cctgatcaag 3227041 acagcctttt gtatgataga tcatgcaata ttcgtcctga gcattgatgg caattccgag 3227101 ggcgatcagc tgtttttctc tttcagtcag agaattcccg gcaaagcact gttcagtaaa 3227161 ttcgttaaat tttcttccca tcagcggcat cttttgttca aatgtgccta aaccatgttt 3227221 atattgtttt aacgcgtcct gcatgcttcc tctgtcttga ttcaaagaaa atccctccat 3227281 ctgtttaaca ttccttttta ttatgaacag cttttaggaa aatacgcgaa aaaaaccccg 3227341 gaattctcat ccggggtttc agtcttattc agatacagga agcacagctc cgtcgtattt 3227401 tttctcgatg aagtctttga tctttttaga gtgaagaact tccatcagcg ctttgatttt 3227461 tgcagaatct tcttcgcctt ttcttactgc gatgatgtta gcgtatgggt tgtttttcgt 3227521 tgattctact tcaattgcgt cttttttagg atttaattta ttttggatcg catagtttac 3227581 attgatgaag accgcgtctc cttctttgtt ttcatatgct tttgccgtta attcaggcgc 3227641 tacttttttg aattcaaggt ttttcgggtt tttcttaatg tctttcaatg ttgcgtcaac 3227701 tgtttccact ttagaatcaa gagtgattaa tccagcgttt tcaagcattg caagcatacg 3227761 gccttgttca gcaacgttgt ttgtcagaat gattgtcgca ccgtctggaa ggtctttcag 3227821 tgatttgtat gttttagagt aaataccgaa tggctctaag tgaacagcgc cggcattcac 3227881 aagtttgtaa tctgtgtttt ctttcatttc ttgctcaagg taaggaatgt gctggaagta 3227941 gttcgcgtcc acttctttat cagctaaagc tttattgtac attttgtaat cactaagcac 3228001 tttcactttc agcgtatagc ctttttcttt cagcaatggt tcagcttctt ttaaaatttc 3228061 cgcatgcggt gtttttgttg ccgcaacgac aatttctttc ttgccggatt cagcgccgtt 3228121 attcgaaccg caggcagcca taactcctgc aaatacaagc agtaatgcac ccaaaaatag 3228181 ctttttcaat gtaaatcctc ccttatcgtt tgtctataat atttgttatt agatcaccga 3228241 tgatttgaat aataaacacg atgattaaaa taaacacagt agcaacgaag gtaacatcag 3228301 cgttattaga ctgatatcct tctacgtacg caaggtttcc aaggcctcct gaaccaatgg 3228361 ctccggcaat tgccgttgaa ccgattaaag cgatggctgt aaccgtaatg ccagaaataa 3228421 gagcaggcat tgattccgga atcagcactt tgaaaataat cgtagacgtt ttcgcgccca 3228481 ttgatttagc tgcttcaatc acacctttat ccacctcacg cagcgcgatt tcaacaaggc 3228541 gcgcgtaaaa tggtgccgag ccgattacca gcgccggcaa tgcggcgttt ggccctaaga 3228601 tcgtgccgac taaaaatttc gtaaaaccta atagtaaaat aattaaaata aggaacggaa 3228661 tcgatctgaa tatgttaaca acggctgcaa tcactgagtt gaccgcttta ttctgccaga 3228721 ggcttccttt gctcgtcaga aagagcagca agccgaggat gaccccgatg acaaaagcaa 3228781 acagtaaaga aatcagcgtc atataaagtg tttcatatgt cgcgttccat aattcagtta 3228841 aatcaacgtt cgggaagtat ttttcaaaca ttcgtgatca cctctgcttt cacctgtttg 3228901 tcattaatga atcggatcac gttttgcact tcttcctcgt ccccgtcaat gtggatgaac 3228961 agtgaaccgt aagccccatc cttcgtctgc gaaattttcc cttgcagaat attgacgctg 3229021 acattgaagt ttctgatcat ctctgtaatc agaggctgtt cagctgactc accgacaaat 3229081 gtgagctgaa ccatttttcc tgatgctgta tcatcaagaa ggtgctgaag cgtctctttc 3229141 gtttcttccg gctctgtcac ctgttgaaca aatcgttttg tcatttgttc ctttggattt 3229201 ttgaagacat cgagaacctc gccttcttcg accaccttgc cgttttccat gacggcgact 3229261 ctgttgcaga ttttgcgtat gacatgcatt tcgtgcgtaa tcagcacaat cgtcaaaccg 3229321 agtctttcat taatatcgga caatagatcc agaattgaat ctgtcgtttg cggatctaat 3229381 gctgatgtcg cttcgtcaca aagaagaacc ttcggattgt ttgcaagcgc tctggcaatt 3229441 ccgacacgct gcttctgacc gccgctcagc tgggacggat aagatttttc ttttccttct 3229501 aaacctacca gtttaatcag ttcattggcg cgcttgatcc gctcgctctt tttcaccccg 3229561 gcaatttcta aaggaaacat gatattatct ctgacagtcc gcgaccaaag caaattgaaa 3229621 tgctggaaaa tcatactgat ctcatggcgt gcttttctta aaccgcgtcc atttacttca 3229681 ttaatcttgg ttcccgccac ttccacggtt cctgaggttg gtttctcaag gccgttcagc 3229741 agacggatta aggaactctt accagctccg ctatatccta taattccaaa aatctcacct 3229801 tttttaatgg aaagcgagac gttttggaca gcattgacat ctccatgttt cgacttgtaa 3229861 acttttgaaa catcctgaag attgatcaaa gcaatcacct gccttaacac tattctaaga 3229921 aatcttccgg ttttttctgc aaaagaaaag cctttctgca cacttgagca gaaaggctta 3229981 tataaaatgc ctttctctca tctttcaaag ctgaacgctt cgtgtgaatt ggcaccattt 3230041 caacagtgtt gatggttgcc gggcttcata gggcacttcc ctccacctct cttgataaga 3230101 gaaatatata gtctttttcg tccggaaatt cttaatgtag aatagcacgg cgaatgatta 3230161 aatgtcaata aaataaatga tgtcaacttt tactattata ataatttatt attttttaat 3230221 tttttaaaat cctctgaaaa aatccatttg tcagccagag aatggcttcc agctttaaca 3230281 gggccctgaa tgaccccttt actttgaggc ttccgctctg aataaggtgc tgaagggaaa 3230341 tgtctccgtg caataaatca ataatttccg tttggtttcc gtaaaaggtc aggttggacg 3230401 tttggggcgg agaaactttt ttcatttctc cctgttcgtt tattgagacg gttaaggctt 3230461 ctgcttctcc ttggaaggta atgagcaatg ttgaggcatt caaaaggggt tttaaaaaca 3230521 gatgctgata ctcatcttct aaaacttccg ctttctccat atgtacaacc tcctatttgt 3230581 tggtcataca tacacatttc tctctttgtc gcaagaaccc ctttataaaa cgaacgacaa 3230641 tttcattgga tatgctgaga aatatgtcat aaatgggatg cggaagatga tttttgtttg 3230701 atcagctcat ataaataaga aacggaatga aatgcatatc ctctttcgac catctttccg 3230761 cctttaaaca gcagaaaaca agggacgctt tcaatttgat acgcttttgc gaatgtcgga 3230821 gagtaattga cattgttttg atagaaggcg acatccggca gcatttcttt caccactgtc 3230881 agcattttgc ttgcaagctg gcaggtgccg caaaacggag tatataaata tagaaggtac 3230941 acatcatctt caatgtgatc aagttcgtgt tcttggagtt ctttcatgct atacacctcg 3231001 ggactttctt tcaagaaaaa tagtatggac attcagattc gcacgcagca atacagaagc 3231061 gatatggtgc ctgggcgcag ccgctacttc cttataggct ctgtcgacat ggagatggca 3231121 ggcttcatta aattcacgct tcagctgttt tctcaatttc tcacctgatt catcagcatc 3231181 aactaatata tagacgtctt tatcataaag ctcgtcagcc aattcctcga gcctcagctg 3231241 gctgattgtt ccgtttgtgc agataatgcg catcggttca ttcaggacgc tttcgatttt 3231301 ctctttatct gatttcccct cgacaatcat aaccttttcc agctcatcca tcttcatctt 3231361 gttcacctgc cgcgtcaaat ttgaaatgtt cagattgtaa aagaaggcag tgaaattcac 3231421 cgccaacatt aacaccagcc gttttcgtag tcacaatcta catattttgc gtcgtctcca 3231481 gagaccacat cggctgtctt ataaaatttc tcattttcaa aggaataacc ggacttaagc 3231541 tcatattcat tcatgcttgt catttggccg atcatctcat tatcatgata taacgagagc 3231601 cggccatttt gaaagcggcc tgtcacgtca ttggtgacat cgagcttttg tttgtcgaaa 3231661 gccatattgg acacctccca taacgttagc gtgtccaatt gcttttacgg ctatcctgtt 3231721 ttagtcttct tgtgtcatct cttcgtattg ctctgctgtc atcagttttt caatttcaga 3231781 agcgtcagat ggctcaacga cgatcatcca tgctttttcg tacggagatt cgttgacgaa 3231841 ttccggactg tcatcaagat cttcgtttac ttccacaacc gttccgttaa tcggtgcata 3231901 aagctcagat accgttttaa cggattcaac actgccgaat ggctcgtccg ctttgatttc 3231961 agcgcccact tcaggaagtt cgacaaacac gatgtcgcct agttcggact gggcaaaatg 3232021 cgtaattccg attctggctt tttctccttc aacttttacc cactcgtgtt ctcctgagta 3232081 acgcaaatct tttggtatgc tcaattgaat ccctccattt tttacagcac tacaataaga 3232141 agataccaca cttttcaaaa aaaatttaca ttaagcccag ttttcttcaa attggtcttc 3232201 tttaaatccg acagtcactt tttcgccgtc tgttgtaagc gggcgtttaa ttagcatacc 3232261 atctgaagcc agcagttcga gctgttcgtc ctctgacata tgatacagct tttccttgag 3232321 attgagctcg cggtatttca tgccgctcgt gttgaaaaat ttcttgagat ccagcccgct 3232381 tttttcataa agcgctttta attcttcttt gcttggcggc tgctcagcaa tatgtatttc 3232441 gtttatttct ttcccatgct cttcaagcca cttctttgct ttgcggcacg ttccgcattt 3232501 agggtaccag taaaaagtta acgacatctt cttccccctc aataaaataa tcgaggttat 3232561 tttaacacag tttgttttaa aaacctaaaa cagtgcttct taaaaaagag ctccgcgcat 3232621 gcggagctca tggccaatca gacagtatat ttctcagcct caaaaatgcc tgccgccgcc 3232681 tcgcgttttt tctgaatcac gtttttaggc gttacgcgtg tcagcttgcg cagagcggaa 3232741 agcatcatgc ggagtgaatc tccttcttcc attgcgataa gggattcctt tgcatgcgct 3232801 tcgatttcgt taaaggcctc ttgaacgaaa atttctgtgt acagcacctt ttgcgctgct 3232861 ttttcagcgc cttgtgcggc aatggccttt tccgttctga gcacggctga ttccattgcg 3232921 tatacattgc tgacgatatc cgctacgttc acgagaattt cttgctcacg atcgatcgct 3232981 tttccgtatt tttgcgcggc taggccggca gcaaacaacg caattttttt ggcttgcttg 3233041 acgatatatt tctcctgctc taagacgccg cttccaggct cttcaggcat aagcatcatg 3233101 agttcttcct gcagcgactg cgctttttcg aataaaggca gctcgccttt aagcgctttt 3233161 ttcaggaagg tgcttggcac gattaaccgg ttgatttcgt ttgtgccttc aaaaatccga 3233221 ttgatccttg aatccctata ggccctttct acttcgtatt cctgcataaa gccgtagcct 3233281 ccatgaatct gcacgccttc atcaacgata taatcaagcg tttcagagcc gaatacctta 3233341 ttcagagagc attcgatggc gtattccgca atcgatttgg cgatttgccg gccgtccttg 3233401 agatcttcgg ccgtgaactg gctcatattg tcttcaaaca gcccgacggt tctgtataca 3233461 gagctttcca tcgcatacag ccttgaggcc attgtcccga ttttttcctg tgtcaatgaa 3233521 aaaccagcaa tcggcgtttt aaattggcgg cgctgatttg cgtatgccgc agacagctcg 3233581 atgacgcgtt tagatgcgcc gattgtgcca accgccagtt tgtaacggcc gatgtttaaa 3233641 atattaaagg cgatgacatg ccctttgccg atttctccga gcaggttttc ctttggcact 3233701 tcagcttgat ccagaatgag ggttcttgtc gatgatccct tgattcccat tttcttttct 3233761 tccggtcccg tggagacacc cgggaactct ttttctacaa taaaggctga aaacttgtcg 3233821 ccgtctacct tagcgtaaac tacaaataca tcggcaaaag cagagttggt aatccactgt 3233881 ttttcccctg ttaatacata atgggttcct gcttcattca gcacagctgt tgtttttgct 3233941 ccaagtgcat cagacccaga gccaggctca gtcagagcat aagcggcgat cttttcgcct 3234001 gaagcgagtc caggcaaata ttttttcttt tgttcttctg acccgaaaaa gacgatcggc 3234061 aaggaaccga taccgacatg cgcgccataa gaaagagaaa agcttcccgc acgcgaaaat 3234121 ttctcagtga tgagtgccga gctgatttta tcaaggccga gcccgccgta ttcttccggc 3234181 acatcggcgc caagcagccc tagttcgccc gctttcttca acagtctgac agaatgctcg 3234241 aattgatggt tttcgatatc atctatatga gggagaacat cttgctcgat gtaatcctct 3234301 gttgttttcg caatcatttt atgctcgtca gtgaaatcct ccggtgtata catttgatcg 3234361 tatgtgacat cctcgattaa aaatccgccg cctttttgta cgtcagccgc tttttttgcc 3234421 atttgttttt ccccctttag cataattcaa atacaccggc cgctcccatt ccgccgccga 3234481 tacacatggt cacgactcca aattgctcgt ttctccgttt catttcatgg atgagtgaga 3234541 gtgtaagctt tgtgcccgta cagccaagcg ggtgtccaag cgcgattgcg cccccgttga 3234601 cattcacttt ttcttcatca attcccaatt ccctgattac ttgaatggcc tgtgaggcaa 3234661 aagcttcatt cagttcaaac aagccgatgt cctgcagctg aagtccggca agcttcaaag 3234721 cgcgcggaat cgcttccacc ggtccgattc ccatcacttc cggcggcacg ccgcctaccg 3234781 caaaggagcg gaatttcaca agcggcgcca ggccaagagc atcggctttt tcccggtcca 3234841 tcagcatgac agccgccgct ccgtcactcg tttgtgagga attgcccgca gtcaccgtcc 3234901 cgtcaacgga aaaggccggg cgcaatgtcg ataagatgtc tgcagtcgtt tgcgggcgaa 3234961 caccttcatc ctgagaaaac acaaactgtt tttccatagg cttatggtct tctccgattt 3235021 ctgtcaccgt cacttcgacg ggtacaattt catctttaaa ttttccttct gcaagggctt 3235081 tagcggcgtt ttgatggctg cgaacggcaa acgcgtcttg atcctcacgg gagacgccgt 3235141 attttttcgc gacttgctcg gctgtgtgcc ccatgctcat ataatattcc ggtgcctttt 3235201 ctgccaaagc aaggttcgga cgggtaacat gccccatcat cggaacttgc gacatggatt 3235261 ctgctccgcc ggcgatcgct gtatcgtagg cgcccagcat aattttttct gctgcatacg 3235321 caatagactg aaggcctgaa gagcaatagc ggttaactgt aatcgccgga accgtgtacg 3235381 gcaggcccgc gagcgcaccg atatttctcg ccatattaag cccctgctcc gcttcaggtg 3235441 ttgcacagcc gataatcaag tcatcaatat tgccttcgta gccgcctgcc cgtttcagcg 3235501 tttcttttac acaaatcgct cccaaatcat ccgggcgaac ggtggccaac gatccttttt 3235561 ttgcttttcc aaccggtgtt cttgcacctg acacaatgac tgcctctttc ataagctccc 3235621 tcctaattcc gtaaaggttt acctttcaca agcatatgct gcattctcgc ttgagatttt 3235681 gcctctcctg acaaactcaa aaacgcttct ctttcgatct ccaataaata ctcttcatca 3235741 acctctgtac caaacggcac ttttccgccc gcaatgacat aagcgagttt tttcgcgatc 3235801 ttaaaatcat gctcagatat atagccggac agcttcatct gctcagcgcc aagcaagagt 3235861 gccgcataac cggtttctcc cggcaccttg accttttctt ttacaggcgg ccgccagccg 3235921 gtatcgtata aagatgcggc cagctgcttc gcatcgtata acaggtggtc ttgattcacg 3235981 ctgatctgat ccgtttcttt taagatgttc atctcacgag cctcttgagc ggaagcggac 3236041 actttcgcca tcgcgattgt ttcaaatgtt ttcattgccg cattcatcgg atcatggccg 3236101 cggcgaagat ggttgatgta cagctctttg ttacctcctc cgccagggat gaggccgaca 3236161 ccggattcca caagtcccat ataggcttcg cttgccgctt gaatgcgcgc cgccggcagg 3236221 catgcttccg ttcctccgcc gagcgtcatg ccaaatggcg cggcgacgac cggtttcgca 3236281 ctgtatttga tcttcatcat cgtctcctga aaacggcgga tcacaaaatc aacttccaaa 3236341 aagttgtcat cttggacttc cattaagatc atggcgagat tcgcgccgac gcagaaattt 3236401 ttcccttgat tgccgatgac aagccccttg taattccgtt ctgtttcctc taatcctttg 3236461 tggatcattt gaatgatatc gaggccgatc gcattgcttt tcgaatgaaa ttcaagaagg 3236521 gccacatcat ctccaaggtc aattaagctt gctccgctgt ttttcgcaat cacgcctttt 3236581 gtttctttaa gtgcttgtaa atgaattcgt tttttgtttt ctttcacggc tctgtattcg 3236641 ccgcggtcat aataaaatac cgttccgttc tctttgatgt agaaggtttc atttcctttg 3236701 tccagcatct cttttatcca gccaggcata tctgctccaa gctgctcaag cttttccgct 3236761 gactgcttga ggccgatggc gtcccacatc tcaaaaggtc ccagttccca gccgaatccc 3236821 cacttcatgg cttggtcaat cgcatgaata tcatcggcaa tctcgccaag cagctcggct 3236881 gagtaaagca gggtttgaga agtgatattc cacagcaaac ggccggccct gtcatccgaa 3236941 taaataagcg ctttcatttt ggcttttgtc ccttttgcct gttttgccgc ttcaagtgcc 3237001 ggtgatttca tttttgtccg ctcgccgtaa gtaagcgtca ctgggtcaag ctcataaatc 3237061 gtttttcctt cttttttata aaagccttgg ccggccttgc ttccgatcca ccctttttcc 3237121 agcatatcgt tcatgaagct tggaatgcga aacacttctt tttcatcgcc atcagctttg 3237181 tcatacacat ttcgggcaac gtgggcgaat gtatcgaggc cgaccacatc aagcgttcta 3237241 aaggtggcgc ttttcggcct gccgatcagc ggtcctgtga tcgaatcaac ctccccgacc 3237301 tgataaccgc ctttcagcat ttcttggact gtcacgagaa gcccgtaagt cccgatgcgg 3237361 tttgcgataa agttcggtgt gtcctttgct gtaacaacgc ctttcccgag gacattttct 3237421 ccgaaagctg tcataaactt taaaatatca ggatccgttt ccttaatcgg aatgatctct 3237481 agcagcttta aatatcgtgc gggattaaaa aaatgcgttc caagaaaatg ggctttaaaa 3237541 tcatccgacc ggccttcagc catttcctgc actgatatgc cggatgtgtt gcttgagacg 3237601 atgcttccag tctttcgatg ttcatccaca agagcgaaaa ttttcttttt gacttcaagg 3237661 ttttcgacaa cgacctcaat aatccaatct gcttctttca gtttttctgc atcatcctcc 3237721 agattgccag gtgtaatata ggaggtattt ttcgctgatg tgaggggagc gggcttttgt 3237781 ttcagcagtt ttttcatcgc ctgccggctc agcctgctgc gcacctccga actgtccttc 3237841 gtcagcccct ttttttcctc ttcctttgtc aaatcgttcg gcacaatatc tagcagcagg 3237901 acaggaattc cgatgttagc caaatgcgcc gctatcccgg aacccattac ccccgatcct 3237961 aaaacggctg ccttccgaat gtgtttgtgc atgagatatc ccccttgaac attgaatgaa 3238021 tagtcattca ttttttgact aaaaaaaatg aaacccgttt cttctttcat cttaaaagat 3238081 ttccggttcg acttcaatag ctaatttgtt atttttttgt atgaagccta taaaagtcgg 3238141 gcaacttaag cccggaggtg aagggaatgg tacgagagaa aaaaaatccg tcttcagcgg 3238201 cagtcagcgc ggcgagcgta aagggagatg ccggtccgac tcagcattac ggcggcggaa 3238261 aacggacaag tcaaaatcag cagtataaaa aacataacat gggacaatca taatgcagct 3238321 gcttcccacg gctgctttca ctttttcaaa attcctttta acacaaacgc tgcattggca 3238381 ggccgttcgg caattcttct cataaagtag ctgaaccagt ccgttccata tgggacatac 3238441 acacgcattc tgtagccttc cttggcgagt tccttctgac gctccggcct gatgccgtat 3238501 agcatttgaa actcaaattg cgatgcgggg atttgatgtt cggcgacgag ctgtttcgta 3238561 aatgcaatga tgtcatcgtc atgtgtggcg acagccgtgt agttcccgct taacaactgc 3238621 agctttatta agctctgaaa atgaaggtcc gtgcctcttt tgtcgggaaa cgctacagcc 3238681 gcagattctt tataagcgcc ttttacaagt ctgagattcg gctttaagtc ccgcatcttt 3238741 ctgatatctt ctgccgcccg gtacaaatac gcctgaatga ccgtgccgag cttctcaaat 3238801 tcctgtttgc attgcctgta aatagaaagt gtctgttcat aatgagaata gtcttccata 3238861 tcaatggtca cagcaacatc atattgcttc gcaacggaaa gaatggcgcg caaatgagta 3238921 agagcaagtt cttctgaaag atcgagcccg attgaggtca gcttaagtga aagctctgaa 3238981 ttcaattgat gttcggcaat ggcttgaatg gctttcttgc attcctctgc gacttggttt 3239041 gcttcttttt ccgaagctgc atactcgcct aaataatcaa ttgttgcaca caaaccggat 3239101 ctgtttagcc ttttgacggt cttaaccgcc gattcaatcg tatcccctgc gacaaacctt 3239161 cgtgctccaa gccgcgttcc gtatgctttt gcgaacttgg taagtgtttt attttgagat 3239221 aagaataaaa acacatgtct caacatccga ctccctcccg ccgtcatctt caaaacacct 3239281 gtatataact cccagtctga aggaaactat aaaatgaaca gaaaccaaag gaggatcaca 3239341 atggataatc agcagcaatc tcaaatgccg ccttccgtta tttcgacaaa ggatcatttg 3239401 tatctcaatg acatgctgaa ctggaatttg ctcgcgatga aaaaagcgca tttcatggcg 3239461 cagcagtgcc aggatcaaac gttaaagcaa gaactcgacc gcgtcggaca catgcatcat 3239521 gatcactatc aaagaatatt aaagcacctg cagccaggcc agcagcagtc cggctacatc 3239581 caataaggag gcgccagaat gaatcagcaa aatcaaaaaa tcagcaaccc gcagacacct 3239641 gtaccgacaa catcggaaat gaatgacaga gatttcgtca acgaattgct gacaaccgaa 3239701 aaatacatga caacagctta ttgcactgcc ttgcacgaat tcagccacga gtctctttat 3239761 caggatattc aatccatttt tgatgagtca caaaaagcgc aaagaaaact atatgatctc 3239821 atgttccaat atggatggta ttctgttgaa gcggaggatt cacaaaagct gcagcagtcc 3239881 tatcaaaaat tccagcagac cattcagcag cagtctcctt atcagcaata acaacattag 3239941 taaaaaggat acgatgttct ttcgggcatc tatccttttt ttgtgtaaaa tcagttgact 3240001 tttcatttac gcttatttat atttaataag cattaactat tttgtcatta aaatatatat 3240061 acagtgtatg taacagaggg gaaatgaata tgaagagtgc ggatcagtta atgtccgata 3240121 ttcaattatc gcttcaggcg ctctttcaaa agatacagcc tgaaatgctg gaaagcatgg 3240181 agaaacaagg tgtcacccca gcgcagctgt ttgtgctggc cagcctaaag aaacacggca 3240241 gcctcaaagt ttctgaaatt gccgagcgta tggaggtgaa gccaagcgcg gtgacgctga 3240301 tggcagatcg ccttgaacaa aaaaatctta tcgccagaac acacaacaca aaagacaggc 3240361 gagtgattga tctcagtctt actgacgaag gagacataaa gttcgaggag gttttggcgg 3240421 gcagaaaagc cataatggcg cgctatcttt cctttttgac ggaggaggaa atgctgcagg 3240481 cggcgcatat tacagcaaaa ctcgcacaag cagcagaaac ggatgaaaag caaaacatga 3240541 aaagaggaaa cggatgaaaa tgagtaaaga aggcaaacaa tcaaaacgaa cgttattaat 3240601 aacaggctta attattgcca tgtttttttc agcccttgac ggtaccattg tcggaacggc 3240661 catgccgaaa attgtcggtg atctgggcgg tttgagcatg atgacctggc tgacaactgc 3240721 atatttgtta acatcaacaa ccattgttcc aattgccggt aaactggctg atttattggg 3240781 acgccgcatt gtctatgtat caggtttgat tatttttatg gccgcttctg ctttgtgcgg 3240841 aatggccaac aacatgacgg aattgattat cttccgtgga ctgcagggca tcggcggagg 3240901 catcatgatg ccgatggcga tgattgtcat cggtgacttg ttcacaggaa aacagcgtgc 3240961 taaattccaa ggtgtctttg gcgcaattta cgggctggct tcagtgattg ggccgcaaat 3241021 cggcggctgg attgtagact cgttaaactg gaaatgggtt ttctatatta acctgccagt 3241081 cggaattatt gcggttattt ttattgccag gggattacag ggacgccagc agactggtcc 3241141 gatcaacttc gatatcgctg gtattttcac aatgattgtc ggtgtggtca gcctcctgct 3241201 cgccttaagc tttggcggaa aagattatgc atgggattca tggcagattc ttgggttgtt 3241261 cgctctcgca ctgatcggca ttgtcagctt tatcatcgta gaatcaaaag caaaagagcc 3241321 aatcctgcca atgtatttat ttaaaaacag aacatttaca tttctaaact tgatcggctt 3241381 ctttatgagt atcggtatgt ttggcgccat tacgtttgtt cctttcttta tgcagggaat 3241441 tgtcggtgta agtgcgtctg aatcgggtac aattatgaca ccgatgatga tttctatgat 3241501 tatcacaagt atcatcggcg gacagcttgt ttataaaatt gggattaaac cgcaaatcat 3241561 tacaggcatg ctggttatgg ccggcggatt cctgctgtta acgacattgg atctcgacac 3241621 gagcaagctt gtcgctacat cttttatggc gattattggt ctgggaatgg gtcttgttat 3241681 gccgattctg acattggctt tacaggaaag cttttcgaag gaggagcttg gagttgtcac 3241741 ttcatccagc caattcttcc gttctatcgg cggaacattc ggcattacca tgctgggagc 3241801 cgtaatgaat gcgagatcag gaaatctatt aacagataaa ttggttccat atttagactc 3241861 tcttccggca caggcaagct cgtttgccgc ccagctaaag ggtatgattg atacaaatcc 3241921 gcaagggctg ctgcaatcac tgttcagtcc ggacgcggtc aaacaaatcc ctgcggcttt 3241981 ctcatcccat attgtgccga ttttaaaaac atcgttgatg gattcgctcc acagcgtgtt 3242041 ttatacgggc ctgatcttta tcgcagtcgg agccgtattc accttgttct taaaacctat 3242101 caagctatca aataagaaag cggaagacca acaagaaaaa gagaaggcgg caaaagccgt 3242161 tgaatcacct tcccattaat agagcacccc gcgggtatca atccgcgggg ttttttattc 3242221 aatcatctgg gctcttccat ttccgaaaga ccaatcctca tcctgatttc cggccagcat 3242281 gataaacaca tcttcttttc ttacaccaag ctcggaatga atccggctcg cgattgagcg 3242341 gtaaagtgct tttttctgtt cagttgttct tgactgtttc agtgtaaaat gaatgtatat 3242401 cagttcatca gtacgctcga cttggagata aaatggatca taaaaaaatt cgcttttttc 3242461 atattgtctg atgacttgga aatagtcatc ttccggcaca ttgatttctt caatcatcga 3242521 ttggtggata gtcctgctca gtttttgaag ccacacttcg cttcttcccg accgtaaatg 3242581 aatctgtaca aatggcatct ccccgcatcc ctttctttac agcgtctgtc cgctgtcaat 3242641 tgtgataatt tggcctgtga gtgattcctg ttcaattagt gaacaaatca atttggcaac 3242701 atcatctggt tcagcaatac actgcagcag caaagagccg atcatgcttt tcattttttc 3242761 ttcccgtccg gcccaccatc tcgttgccac agctcctggt gctacaccgc tcactctgat 3242821 ttcaggcgct aaggcgtggg ccaatgattt cgttaaaccg tgcaccgctg attttgatac 3242881 tgcgtaaggc attgatgagc cggcaccagt tatccctgcg atgctgccga cgtttacgat 3242941 cgccccgtcc ttgcttttct tcatgaacgg aaccactgcc cgcgcgcaga aaaacatccc 3243001 tttcacattg acggcataca gctcatccta gacgtcttct gtcgcagcct caagatcatc 3243061 cattggaata tgccgtgtaa tgctggcatt gttgactaaa atatcaaccg tgccgtgtgt 3243121 gttcacgatt gcttgaatca tatcctgcac gtcgctgttt ttggatacat ctgcttggat 3243181 ggcgaaggct tgcccgccag ctttttgaat catttccact gtttcctccg cttctgattg 3243241 cgagcgtgaa taattcaccg ccacaatcgc cccacgcttt gccaattcca tactggctgc 3243301 ttttccgatt cctgtgccgc cccccgttac gagagctatt ttgttcaaga cattcattgc 3243361 cgccactcct tgctgttgac taaagtatat ttctgattcc attgtaatcc agctttgatg 3243421 ttacgtataa tgattgttaa agatactaga tatcactcag attgatagta aacgaacgga 3243481 ggagttcaaa atggaaagcg gagatttacg tgtgtttcaa atggtagctc gtgaagggac 3243541 cattacgaaa gcagccctgc agcttggcta tgtacaatcg aatgtcacgg ccagaattca 3243601 acaattggaa gctgagctgg gtaccacact gtttttgcgc cataatcggg gcatgacact 3243661 ttctgcaagc ggaaaattgc tgctggacta cgcaaataaa attataggcc ttcttgatga 3243721 agcgtctaaa gcgctctcat cctccgcaga accaagcggg ccgcttatga tcggctgcac 3243781 tcagacaacc gccgcggtaa ggcttccaaa gcttctggca tcttattatg aagaacatcc 3243841 aaacgtccag ctgtctttaa caacaggaca tacgcaattt ctccttgata aagttcttcg 3243901 ttatgaattg gatggcgcgt ttatcggatg cgaatgccat catcctgagc tcgaatccta 3243961 tcctgcgttt gaggaagaac cagtagttgt ttcggctgcc tccgtgcccg atgttgagga 3244021 agccatcaca aagccgattc tcgtttacag cacaggctgt tcgtatcgag aaacacttga 3244081 aaaatggctg cgttccgtcg gtgtcacaca gccggtcatt atggaatttg ggacgcttga 3244141 agcaattatc ggcggggtta cagcaggtct tggcatctcg ttgctgccaa gaacggttgt 3244201 gcagaaacat gaagcagaag gatcaattcg attgtacccg ctgcctgaag ctctcagcca 3244261 gatgaaaaca gagtttattg ttcgaaaaga ttcgtttatc agcagcgcgc tgagaacctt 3244321 tatggattcc tttacgccag ttaaaacggc tgaatcacaa aaaagcagtc tgctataatg 3244381 aacagactgc tttttggcta ttgtttgttt cgatgcgctt catttaattc cttaatatgc 3244441 tgaatgatct ctttaatgcc ctgcttcgcg tcggggtatg tcgcattcca atgcttagcg 3244501 agcggaggca tgcttttggc tatatgggtg tacaaaatcc attgcttcac ttcttctttt 3244561 agctcatcgt ttgtttcacc aagcagaagc tcagtatact tctccagcaa tccatcaagc 3244621 tgctcctgaa gtttttgttc cattttccat cttcctttcg aaaaaacagc aaggagcttt 3244681 ctcaattgaa agctccttcg ctgcgttatt tatccatgtg atgtgaaagc cgcttcctgg 3244741 acaatgcatc tgcccctgcc atgaggaatg caaagaggcg ttccgaagag cgggtcctgt 3244801 gtaacctgac agttcataga aaacacattt tgcacaagat cacaagtgat gacctcttcc 3244861 ggacggcctt ctgcataaat ccgtttatct tttatggcca caagatgatg cgcatagcgg 3244921 cacgccaagt ttaagtcatg gagaaccata acaatcgtcc ggtcttcctt ttcattcagc 3244981 tcaaacagca aatcaagaat ttcaatttga tgcgtcatgt ctaaatacgt cgtcggctcg 3245041 tcaagaagga tgatatccgt ttcctgggca agcgtcatcg cgatccaagc ccgctggcgc 3245101 tgtccgcctg acaaagaatc aacggcacgg tcagccatgt cctcaagctt tgttgcttta 3245161 agcgctcttt caactgcttc ctcatcctct tttgaccact gcttcagcca gttttggtaa 3245221 ggatatcttc cttgcttcac cagctgatgc accgtcagcc cctctggagc cgaaggacct 3245281 tggggcagga ttgcgagctc ttttgcgact tccttcgtcg gaagcttggc aatcgctctt 3245341 ccttccagca gcactgaacc gcctctcggc ttcatcaggc gcgctaatga acgtaaaagt 3245401 gtcgattttc cgcagccatt gctgccaata aatacggtaa tttcaccttt gggaattgtt 3245461 aaattcaact catcaataat aacggcatcc ccgtatccta agctcagcgt ttctgtagaa 3245521 attgcactca tacccataac cgctcctttt tgctggcttt ttagcagcac tatgtattgc 3245581 acgttttcta tatacatgct tttaagtcaa ttgtcatcaa tgcaaatgat tccgatattc 3245641 agccatttga tatggtcata tatccctcat tgtagcagaa aacactgact ttgaaaatca 3245701 ttttcaatta gttttatgga cataattgac gtttatgggt tttttatcac aagattactt 3245761 cttgatttct ctgatggagc cgtccttcag cttcaatttt aaatcgatat gatcataatg 3245821 actgtccaga ttaaatgctg ccagcacact gtgtatcact tctgtttcag ccatttggtc 3245881 tgtcacggaa agctcgctca aaatcatttt catctcatct aacgcttctt ctccttcctg 3245941 attgacaccg gagagcttat cctgtatttc cgctttttcc tgagtcccgt tctttgtata 3246001 gattccttca taacggttat gctcaccatc cccgtagctc acacgaagcg aaaaattact 3246061 gtagggaacg gacttcagct gggtgacggc tgtattttct ccttctgcct gatgctggtc 3246121 ttcattgaaa cggcagcccg caatcagaac cactgcgaga catacagccc cggctgctct 3246181 gatcaaatgc atatgtttcc cccctgtagg attccattta ttttaggtat atccagagaa 3246241 tgaaatcctc attcagagaa gaattgaaaa agccggggca tttaacgcca cggctttttc 3246301 tttaagattc ggtcatttgt aaaaaggttt cggcgtcacg cacagccagc ttgatggcat 3246361 tctcccagaa atcgcgcttt gtgatgtcag cgcccaaatg cttcatcgcc aaatcctcca 3246421 ctgtcataga agccgtatcg cgcaatagcg ccatatactt ctcttcgaat gtgtcttttt 3246481 cttcaagcgc caacgcgtaa ataccaagag aaaacaggta gccgaatgta taagggaaat 3246541 tgtaaaacgg caccctcgtg atgtgaaaat gaagctttga tgcccaaaaa agcggatgat 3246601 attcttctaa cgcattgcag tatgcctctc tttgcgcctc ttccatcagc tcattcaagc 3246661 ggctggccgg taccactccc cgctttcgtt cctcgtagaa tctcgtttca aatagaaatc 3246721 ttgcgtgaat gttcatgaag aacgcaacgc ttctttgcac tttatcctcc agaagaacaa 3246781 gcttttcttc cctcgtctcg gcctgctgga cagtcgcgtc cgccactatc atctctgcaa 3246841 acgttgaagc tgtttctgca acgttcatgg cgtaggaacg gtttaacggc ctgacgttga 3246901 gcattgcttc ctgatggaac gcgtgcccga gttcatgcgc aagggtagag acatttgagg 3246961 cgcttcccga aaatgtcatg aaaatccggg attccccgct gtccggaaaa ctggtgcaaa 3247021 agccgccgac tctttttccg ctcctgtctt ccgcctcaat ccagccgtcc cgaaacgctt 3247081 tttcagtgaa tgaggacagc tttttgccaa acgttgaaaa ctggctggta atgatatttg 3247141 cggcttcatc atacgaatag acctttccgt cagaaccgat cggtgcctcg acatcgtacc 3247201 agctgagttt ttcaaggccg agcatggatg ctttccggtt caaaaactga acgaacggct 3247261 tcttgttttc agtgatgacc tgccacatcg tatcaagtgt ttcttttttc atcctgttaa 3247321 tttgcagcgg ttccttcagg acattctccc agccgcgcgc tttataggtt tcaagccgga 3247381 atcccgccaa atgattcagc gtgctgctga aaatatcttg cttgctctcc caagcttggc 3247441 ggaaacgttc atatactgtt tttctgacag tacggtcttg atgatccatc atattctccg 3247501 cctgaccgac agacaattgc ttgttttcac cgttttcctc atacgggatc gtcattttcc 3247561 cgacaaccat attgtataag tcactccaag cgtgatatcc gtccaccgca aggtttccga 3247621 tcagtttttc cttaccgggg ctaagctttt cggcaaccct ctgtcttctt tcatttaata 3247681 tgtaagaaac atcgcgcaat cccggttttg ttaacaattc attccacacg tcttgattaa 3247741 tgtccacaag tttatgatct aatgtaacga gcgacgattg aaaatctgcg gaaagccgat 3247801 tcatgaggcc tgatgctcta tagccttttg atcattgata ttctgggcct ggaggcaagc 3247861 aacaaaagcg ccggcctgct gaagcttgac ggatgtctgt tcgaataaat caagcaacgc 3247921 ggtcagccct tcagcctctt caggcgattc aggcacctga aacgcatcag tcctgtcttg 3247981 aaatgcacgc agactttgtg acagcttctc aatataacct ttgaattctt ccgattggct 3248041 cccgccctta aaaaatgaat caagatccca tctttggcct accccttgca gcgccatatc 3248101 acaaaacccc tttccttctt tcgttctatt atagaacaat tctgaattat tgtataaaaa 3248161 tttctattac aggcgtcatt tcgtgttcag gatagtacaa tagctgtagc agtttaatag 3248221 gagggttagg atgaataaaa aaatagccat cgtgacagga gcgtccagcg gcttcggtct 3248281 gctggcagct gtaaagcttg cccgatcatt tttcgtgata gccacatcaa gacagcctga 3248341 aaaagcggaa cagcttcgag aattggctgc agcacacaat gtgtctgatt ctattcacat 3248401 tacagctctc gatgtcaccg atgaacaatc tatagtctca ttcggaaaag ctgttagtgc 3248461 ttacgccccg atcgatttac tcgttaacaa cgccggaacg gcttatggag gatttatcga 3248521 ggatgtgccg atggaacatt tcagacaaca atttgaaacg aatgtcttcg gtgtgatcca 3248581 tgtgacaaaa accgtgctgc cttacataag aaagcatggc ggcgcaaaga ttataaacgt 3248641 gagcagcatc agcggactga caggattccc agcgctgtcg ccatatgttt cttccaagca 3248701 tgcattggaa ggtttttctg aaagcctgcg tatcgagctg cttccgttcg gtatcgaaac 3248761 cgctttgatc gagccgggct catacaagac atcgatctgg tcaacgtcat tatcaaattt 3248821 tatgtcggtg cctgctgacg attcagccta tcatcaatac tataaaaaga tcctttccta 3248881 tgttcaaaaa aacggagaag aaagcggaga tccccaagag gttgccgacc tcatttatca 3248941 attggcaaca aaacagcaca taaagaattt gcgatacccg atcggaaagg gcatcaagct 3249001 caccctgctg ttccgatcgc tttttccttg gtctgcgtgg gagtctatcc tgaagaaaaa 3249061 gctattcagc tgatctaaat tataattatt ataatttagt attgattttt atttagtata 3249121 tgatataatt aagtcaacag atcacaagga ggacgttatc ttatgaaaac tgaaaacgca 3249181 aaaacaaatc aaacattagt tgagaattca ctgaacacac aattatcaaa ctggtttctt 3249241 ttatactcta agctccaccg tttccattgg tatgtgaaag ggcctcattt ctttacattg 3249301 cacgagaaat ttgaagaact ttatgaccat gcggctgaaa cagtggatac catcgctgag 3249361 cgcctgctgg cgattggcgg acagcctgtt gccacagtga aagaatacac tgagcatgca 3249421 tctatcacag acggcggaaa cgaaacatca gcatcagaaa tggtacaagc attggtaaac 3249481 gactacaaac aaatcagcag cgaatctaaa ttcgtgatcg gcctggctga agaaaatcaa 3249541 gacaatgcga cagcggactt gtttgtcgga ttaattgaag aagttgaaaa acaagtgtgg 3249601 atgctttcct cttatttagg gtaacaaaaa agctgaacct taatcgggtt cagctttttg 3249661 ttttttctta gcttgaactg ctttctgtct gcttggtcag tgttgcgttc aacgttttcg 3249721 tttttccctt tcgcagcact tggattgttg ttttatctcc gacttttaag tctttgtaaa 3249781 ggatctgacg gatatccgca ctgctttcca cgtctttacc gtttagtttg acaatgacat 3249841 cctcagattt aatacctgct ttttctgccg gcgaatttgc ttgaacttct tttacataaa 3249901 cacctttgcc caattgatct ccaaacaggc cgagcgtatt ttcctgatag gtttcaggaa 3249961 cttgtgacat gtcaatcatc tgcacgccta aaaacggacg gtccaccttc ccgttttgca 3250021 gcagctggtc aacaatcggc tcgacatcat tgcttgggat cgcaaatcca agtgattcca 3250081 cgccgctttc gctcaccttc aagctgttga tgccgatgac ctggccgctt gcattgatta 3250141 atgggcctcc gctgttcccc ggattgatcg ctgcatcggt ttgcagcacg ttcatttcca 3250201 ccgtcccctg tgttgtatcc acatcaattg tccggttcag tccgctaatg ataccttgtg 3250261 tcactgtacc ggaaaactgc tgtccgagcg ggttaccgat agcgattacc ttttcgccag 3250321 tgcgcagctg tgaagagtca ccaaagctcg ccactttttt tacattcttg ccgctgattt 3250381 ccaaaactgc caaatcagta atggtatcgc tgccgacaag cttggcagtt tccgtttctc 3250441 cgttgtatag cgtaacagtc agcttgttcg cgccttcaac gacatggttg tttgtaatga 3250501 tatacgcttt atcgctgtct tttttgaaaa taacacctga cccggttccg ctttcacttt 3250561 ctgagctgga gcctcctccc gtgccgaatg tgttattttg agaggtttgg atatttgaga 3250621 ttccgacaat cgtaggctct aaatcctcta ccatatcagc gatgtttgat gcgttcgtta 3250681 tcggcgccgt tgtaaaatta tcagactgca cctgtttatt tgcggaagcg gtttcggtcg 3250741 cctgattttg gtctgacggc agataaggcg cgatgccaag catgaggccc ccgccgataa 3250801 taccgcctaa aatcgggctc agccatgcgg ctctccgttt cttttctttt ttcacagccg 3250861 tttcttgctt ttccatttct aaagcagaag ccgtttcctg ccgtcccgct tcatacgaca 3250921 caggcgcgtc aagcaattct tgttcagaat gtccaatcag cttctggttt tctgtattct 3250981 gctgttctgt atgtgaaggt tcagtttgat gttgatcgtt ttggccatca cgtcgataat 3251041 ccatgttctt acactccttt aacggttatt catttatcgt tacatattca tcgcatgtac 3251101 aagttcaatt gtcccaataa tgaggagaaa agcaaagcac caaaatagaa tatgtttgat 3251161 catcctacat cttcctcgct ctttttctct tcctttcttc ccttaaccat atcataaaca 3251221 aacattgtgg gataaaaatg aaaagaatat gtgaaattat gaaaattgcc tgccgtatgt 3251281 taaaactagt ttataatgac gttgaaagga tgtgaagagc cttgtcatac accatttatc 3251341 tagttgaaga tgaggataac ctgaatgaac tgctgacgaa gtatttagag aatgagggct 3251401 ggaacattac atcttttacg aaaggtgaag acgccagaaa gaaaatgaca ccgtctcccc 3251461 acctatggat tctcgatatc atgctgccgg ataccgacgg ctatacatta ataaaagaaa 3251521 tcaaggcgaa agatcctgac gtgccggtca tttttatttc cgcccgagat gcggatattg 3251581 acagagtgct tggcttagag cttggcagca atgactacat ttcaaagccg tttttgccgc 3251641 gggagctgat tatccgtgtg caaaagctgc tgcagctcgt atataaggaa gctcctcctg 3251701 tccaaaaaaa tgaaattgcc gtctcctcgt atcgggtcgc tgaagacgcc cgcgaggtct 3251761 atgacgaaaa cgggaatatc atcaatttga cgtcaaagga atttgatctg ctgctattat 3251821 ttatccatca taaagggcat ccatactctc gtgaggatat cctcctaaaa gtgtggggac 3251881 atgactactt cggaacagac cgggtcgttg atgatctcgt ccggagactg cgcagaaaga 3251941 tgcctgaatt gaaggtggag acgatttacg gtttcggcta caggatgatg tcatcatgaa 3252001 aaacaagccg ctcgcgtttc agatatgggt tgtcatatcc ggcatcctgt tagcgatatc 3252061 gattttactg cttgtgttat tttcaaacac gctgcgagat tttttcacta atgaaacgta 3252121 tacgacgatt gaaaatgagc agcatgttct gacagagtac cgcctgccag gttcgattga 3252181 aaggcgctat tacagcgagg aagcgacggc gccgacaact gtccgctccg tacagcacgt 3252241 gctccttcct gaaaatgaag aggcttcttc agacaaggat ttaagcattc tgtcatcttc 3252301 atttatccac aaggtgtaca agctggctga taagcaggaa gctaaaaaga aacgttacag 3252361 cgccgacgtc aatggagaga aagtgttttt tgtcattaaa aagggacttt ccgtcaatgg 3252421 acaatcagcg atgatgctct cttacgcgct tgattcttat cgggacgatt tggcctatac 3252481 cttgttcaaa cagcttctgt ttattatagc tgtcgtcatt ttattaagct ggattccggc 3252541 tatttggctt gcaaagtatt tatcaaggcc tcttgtatca tttgaaaaac acgtcaaacg 3252601 gatttctgaa caggattggg atgacccagt aaaagtggac cggaaagatg aaatcggcaa 3252661 attgggccat accatcgaag agatgcgcca aaagcttgtg caaaaggatg aaacagaaag 3252721 aactctattg caaaatatct ctcatgattt aaaaacgccg gtcatggtca tcagaggcta 3252781 tacacaatca attaaagacg ggatttttcc taaaggagac cttgaaaaca ctgtagatgt 3252841 tattgaatgc gaagctctta agctggagaa aaaaataaag gatttattat atttaacgaa 3252901 gctggattat ttagcgaagc aaaaagtgca gcacgacatg ttcagtattg tggaagtgac 3252961 agaagaagtc atcgaacgat tgaagtgggc gcggaaagaa ctatcgtggg aaattgatgt 3253021 agaagaggat attttgatgc cgggcgatcc ggagcaatgg aacaaactcc tcgaaaacat 3253081 tttggaaaat caaatccgct atgctgagac aaaaatagaa atcagcatga aacaagatga 3253141 tcgaaatatc gtgatcacca ttaaaaatga cggtccgcat attgaagatg agatgctctc 3253201 cagcctctat gagcctttta ataaagggaa gaaaggcgaa ttcggcattg gtctaagcat 3253261 cgtaaaacga attttaactc ttcataaggc atctatctca attgaaaatg acaaaacggg 3253321 tgtaacatac cgcatagcag tgccaaaata gactgtagat gttttgcagt ctattttttt 3253381 atgtgaaaga atagccgtta aaatctctgt aatttgtttt gagcggctgt ttgcattgat 3253441 gaacccattt tttctctgac aaggtctgct tcggatattt gactttctcc actttgattc 3253501 ctctgtttcg caagcggctg atcatttcgt ccaattctct cattctagat tcaccctttc 3253561 gcttgagctt tgaccattcg gtcatctcaa tttataatat aaataataca tgataaaaaa 3253621 acaagttaca ataaggttaa ttttataaca gacggtgtga ctatatggtc atatcctagc 3253681 aggcctccgg gctccgaaag ggtggaacca ttgaaggaaa aagaaaaact gattattgaa 3253741 acagccttaa aactatttgc ccaaaaagga tacaactcaa catcagtcca ggaaatcgca 3253801 aaagaatgca aaatatctaa aggcgctttt tatatttatt ttccttcgaa agaagcgctt 3253861 cttctctcta tgctgaacta ctattatgat aaaacgttta cccgaatttt aaatattaaa 3253921 acgaagggcg acagccccag aacggcttac cgtaaacagc tgaccgtcct ctatgaaaac 3253981 attcttgaac acaaagattt tatcagcatg cagttgaagg agggttctct gccttacaca 3254041 gaagaagtgg agcaatgcgc aaaaaaaatc cgccagtcct cacttcaatt tcatatcgac 3254101 agcctgctga acatctatgg aaaaaaagcg gaaccgtaca ctgctgagct ttgtttttta 3254161 atagagggca tcagccagat ttacctggaa tgcatgattt tgctcgggta cactgtgaag 3254221 ccgtctcaat tagctgatat cattatgaat cgaattgatg atatggtaaa aggcatgtct 3254281 gaacgaaacg ataagccttt catcacattg gaagaggcga gctctttatt cggacctctt 3254341 acgcacggac ggcctgaccc gctgactgaa tcaattgtga aaagcctacg tgacaaaatt 3254401 aacagcttaa acacaaactc ctctcttgaa ttatcggaga gcttggacat acttgaagca 3254461 gaaatgaaga aaaaaacacc gaagctggcg atcataaaag gaatgattca taatctgacg 3254521 gagtctgaag ctctcgccaa agatgcggaa cagcttaaat atttattaaa acagcaacat 3254581 atttagaaga acggctgctt aaaaagcagc cgttcttcct attacgcctt tggttttacc 3254641 atgtcttccg gcttaaccat ttcgttaaat tgctcctctg tcagcaattc aagcttcaaa 3254701 gctgcttctt tgagcgtcaa tccctcttta tgggcaagct tggcgatttt cgccgcgttt 3254761 tcataaccga tatgcgggtt cagcgccgta acaagcatta atgaatttga caggttttcc 3254821 tgaatggttt ctttattagg ctcaataccg acagcacatt tatcatggaa tgaattcatg 3254881 ccgtcactga gcagctgcac agattgcagg aagttgtaaa taataacagg cttaaacacg 3254941 ttcagttcaa agttcccctg actcgccgca aagccgattg tcgcatcgtt ccccatgatt 3255001 tgcgctgcga tcattgttaa cgcttcgctt tgtgtcggat tgactttacc aggcataata 3255061 gagcttcccg gctcattttc aggaatgacg atctccccga tgccgcagcg gggtccgctt 3255121 gcgagccatc tgacatcgtt cgcgattttc attaagtcag ccgcaagcgc ttttaatgcg 3255181 ccatgcgcat aagtgatttc gtcatggctt gtcagcgcgt ggaatttatt cggcgagctg 3255241 ctgaacgttt ggccggtcag cttagtgatc tcttctgaga caagctctcc aaactctggg 3255301 tgggcgttga tacccgttcc gacagccgtt ccaccaattg caagcgcacg cattttatct 3255361 gtcgcttcca aaatcatttc cttcgaacgg tccagcatgt gaacccatcc gctgatttcc 3255421 tgtccgaggg tcagtggcgt agcatcctga agatgcgtgc gtccgatttt gacaatatca 3255481 ttgtatgctt ttgctttttc atccagtgta ttgcgaagct gatcaagcgc cggcacaagc 3255541 tgctcgtaaa cagccaaaac agcggcaaca tgcatcgcag tcgggaatgt gtcgtttgag 3255601 ctttggcttc ggttcacgtc atcatttgga tgaatcgttt gatcagagtt cttctctttt 3255661 aataaagcag tcgcacggtt ggctaccact tcgttcatgt tcatattgct ttgtgtgccg 3255721 cttccggtct gccatacgac aagcgggaag ttgtcatcgt acttgccttt gagcacatca 3255781 tcacaaaccg ctgcaatcgc ttctgctttt tcagcgtcca gattgccgag gcgtttatta 3255841 gctagagcag tgcttcgttt taaaattgca aacgccttca caacacgcat cggcattttt 3255901 tcagaaccga tcttaaagtt ctccttgctt cgctgtgttt gggcgcccca aaatttatca 3255961 gcaggaactt ttacttctcc catggtgtct cgttcaattc tgtattccat ttatgtatcc 3256021 ctccataacg gttgcttcaa tagatcataa ttcgccaatg acacaaaaaa tcctttttat 3256081 ttttcgatct tggcagattt taattttaat tcaagatata cgcgggaatc ctttgaatat 3256141 ttgtattttg gatttgtcct gccgtactcc tttgatgtat aagagacatc ataatgctgt 3256201 tcaaatgatc taatgagctg ttcaatttct tcttgttttc cagctagcct tacctgtgcc 3256261 acttcgtatc ctccgctttc ataaaaaaac ttactccatg aaatactcta acacagtata 3256321 tcattttttt aacaggaaaa gataacctct actaaggttt tggataagag gtgacctcat 3256381 tggaacaaac agagtttaag gaatatatac acgataattt agcattggtg ctgccaaaat 3256441 taaaagaaaa cgatgatctg gtgaaaaaca aaaaaatgct tgcgaacgga ctggtttttt 3256501 actatctcta tttcagtgaa atgactgatg agaataaggt gtcagaagcc attaaaactt 3256561 tgattaaaga tgaggagacc ttaacgcttg accaggtcaa aaaacgcctt gaccagcttg 3256621 acgcaagacc tgttgaaact gcaaaaaaaa cgattgaatc gattctcaac ggcaattgtg 3256681 ctgtgtttat caacggattg gataaagcct atattctgac cacaggaaag aaaaaaacaa 3256741 gaagcctgac agagccgaca actgaaaaag tggttcgcgg cccaaaagta gcgtttgtag 3256801 aggatattga tacaaatctc gctctgatca gacaaagaac ctctcatccg aaattgatca 3256861 ccaaaaaaat catgatcggc gaaaacaagc tgaagcctgc agccattatg tacattgaag 3256921 gcaaagcaaa aaagtccgtc ataaaagaag tgaaggcgcg gcttaaaaat atccagctgg 3256981 aagatatcca ggacagcgga acgctcgagg agctcattga agataataaa tattcaccat 3257041 ttccgcagat acaaaatacg gaaagacctg acaaagtatc ttcagccctg tttaacggcc 3257101 gtgtggcaat tttggtcgac agttcaccat ttgtgctgct ggtgccggtt tctctcggca 3257161 tcctgatgca atccccggat gactactatg aacgctggat ttcagcatct cttatccggt 3257221 cgctgcgctt tgcttctatc tttatcacct tgtttttgtc atcgatttat ataacacttg 3257281 tttccttcca tcaggggctg ctgccgaccg cactcgccgt cacgatttcg gcgaacaggg 3257341 aaaacgtgcc gttccctccg atatttgaag ccctgctgat ggaagtcacc atcgagctgc 3257401 taagggaagc cggactgcga ctccccaatc cgctcggaca gacgatcggc ctcgttgggg 3257461 gcgtagtcat cggacaggct gctgtagaag cgaatctcgt cagttcgatt ttggtcattg 3257521 tcgtcagtgt cattgccctg gcatccttta ccgttcctca atacggaatg ggtctgtctt 3257581 tccgggtgct gcgttttatt tcgatgtttt ccgccgctat tttagggcta tacggcatta 3257641 ttttatttat gcttgtcgtt tatacgcact taacgagaca aacgagcttt gggtctccgt 3257701 atttttcgcc aaacggattc tttagcctga aaaatacgga tgactccatt atccgtctcc 3257761 caattaaaaa caaaccaaaa gaggtgaata atccaaatga gccaaaaaca gactccactg 3257821 aaacttaata cctttcaagg tatttctatt gttgcaaata caatgcttgg ggccggactt 3257881 ttaacattgc cgcgagcgct gaccactaag gctaatacgc ctgacggctg gatcacgctg 3257941 atattagaag gtttcatttt tattttcttc atttatttaa acacgctcat tcagaaaaaa 3258001 catcaatacc cttcactctt tgaatatttg aaggaagggc ttgggaaatg gatcggcagc 3258061 atcatcggcc ttttgatctg cggctatttc ctcggcgtag ccagcttcga gacacgggca 3258121 atggctgaaa tggtgaagtt tttcctgctg gagagaaccc caattcaagt cattatttta 3258181 acgtttattt gctgcggcat ttatttaatg gttgggggct taagcgatgt gtcgcggctg 3258241 tttccctttt atttaacggt aaccattatt attttgctga ttgtgttcgg gatcagtttt 3258301 aaaatttttg atatcaataa tttgcgtcct gttttaggcg aaggccttgg acccattgca 3258361 aactccctta ccgtcgtttc catctctttt ttaggaatgg aagtgatgct gtttcttcct 3258421 gaacatatga agaaaaagaa atacacgttc agatatgcgt ctctaggatt tctgattccg 3258481 attatcttat atatccttac gtatattatc gttgtcggag ctttgaccgc tcccgaggtg 3258541 aaaacgctga tttggccgac tatttctctc tttcagtcct ttgagcttaa aggcatattt 3258601 attgaacggt ttgaatcctt tttactggtg gtctggatta tccagttttt caccacattt 3258661 gtcatttacg gatactttgc cgctaacggg ctaaagaaga catttggatt atcgactaaa 3258721 acaagcatgg tgattatcgg cataacggtc ttttattttt ctctctggcc ggatgacgcc 3258781 aatcaagtca tgatgtatag cgattatctt ggctatattt ttgtctccct gtttctgctt 3258841 ccgttcattc tctttttcat tgtagctctc aagaggagga ttacaacaaa atgaaaatcc 3258901 ggattttatg tatgtttata tgcaccctat tgctgtccgg atgctgggac agtgagaata 3258961 tcgaggaatt aagcttagtg atcggaatag ggctagacaa gcctgacgat gaaaatttag 3259021 agctgacaca gcaaattctc gtgccgaaaa taatcagcgc caaggagggc tcttcatctg 3259081 atccgacaca gctttctatc acaaagggta aaactgtcca tcaaatgatg agaacctctg 3259141 cattaaagca taagcctacg ttttcacagc atttgcgtct cattctgctt tccaaaagcg 3259201 tgattgcgga tcaaattgga atggacgcca ttattaacca gtttgtcaga gacaacggaa 3259261 caaggaggag ttcctacgtc tttatcacca acggccgaac taaggatata tttaacatga 3259321 atgatgaagg cgaacccgca tccaacgtga tatatgatct gacagagaat aataaggtga 3259381 cgatcagaac gatggagcca gttacattgg gggagatctc agaacactta acctctgacg 3259441 attcattcct catccctcat gtcggtaagg aaaacggcaa gctcgcgata aacggagcct 3259501 ctatcataaa aaataaatta tggcaccggg acctcacccc gattgaggtt caaaatatca 3259561 gcttattttc aggcactgtc gagggaggcg tcattgactt gaagcgcgat ggccatctct 3259621 tttcttatga agtatattca agcaatcgga agatcaagac ggcatacaag gacggaaagt 3259681 tcaaattcac cgttacccgc aatattgaag gtcgtctatc tgaggactgg aatcccaatg 3259741 aagactcgtt taaggattca tatattaaaa gtattgaaaa gacagtcgaa aaacgagtac 3259801 acgaaacagt aacgtcattt attacagaga agctgcagaa agagatcaaa gcggacgtaa 3259861 ccgggctggg aaacgaggtc agaattcatt atcctcaaaa gtggaaaaag atttcaagaa 3259921 aatgggatga tgattatttc agcaatgcgg aaatagacta ccgggtcaat gtgattgtca 3259981 gagacttcgg aacgaaaggc gcaaacaaat agcagccgcc taattcacga gatgatttcg 3260041 gtgtgcgtac accgccgcct gcgtccggtc actgacatcc agctttgata aaatattcgt 3260101 aatatgtgtt ttgactgttt taatcgtaat aaacagttcc tcgcctattt ctttgtttgt 3260161 ctttccttct gcgatcaggc agagtatttc gagctcccgt tttgtaagcg attcatgcgg 3260221 gagcgcgttt tcacctgagt ggcgcagcct ggataatact tttcccgcca cttttgactc 3260281 cagcttcggc tctcccttgc ttgcggcgcg gatggcatcg gcgatttctg ccgcttttga 3260341 ggttttcaac agatagctga gcgcgccagc ttcaataacc gggtacactt tgtcatcatc 3260401 aatgaagcta gtgagcacaa taattttcgg gtcggaaagc tcccggcaaa tttgctttgt 3260461 agcttcaatg ccatccatgc cctccatgac aaggtccatt aaaatgacat caggcgacag 3260521 ttccacagca agccgaacac cttcgctgcc gtccgatgct tcgccgatga cttcaatatc 3260581 gggctgcgcc tccaaaaaag ccgcgagccc cattctgacc atttcatgat catcaatcaa 3260641 taatactcga atcacgttcg ttctctcctt tttcttccgg aaaaatcggg accttcactt 3260701 cgatttgagt gccttttcct tctactgaaa tcacttcggc gacaccgccg atttcacttg 3260761 cacgttcttt catagaattc aagccgtatg aggaggcttt cacctggtcc attttaaagc 3260821 cttttccatt atcaatcacc ttcagacgga gctggctgtt ctttatgccc agaatcacgg 3260881 ttacttttga cgcttttgaa tgtctaaata cgtttgaaag ggcctcctgc acgattctga 3260941 acaagtggtc ttcaacaccc ttggatatcg ctgtgtcctg tatatcccac tcaatatcaa 3261001 tcggctgctt ttttcggaac tcgtccaaaa gctccgtaag gccctccttc agcccttttc 3261061 cttcaagggt aacaggccgt aaatggagca gcagcgccct catctcattt tgggcttcgc 3261121 ctgccatatg ctcgaccatc ctgatccgct tgactgtttt gtcatcagca tccttgacat 3261181 gttccagcac ggctgatgtc atcatcgata tggcaaagag ctgctggctg accgcatcat 3261241 gaagatctct ggccaatcgc tggcgttctt ctgagataac cgacttcttc atttgagcct 3261301 gccattccgc acgttcattg gaaagtttct ggagggatgc gacttgaagc tccacgcgct 3261361 tcgccatttc gttcagctga tcagcagcca ggccgatttc atcatcaccg agcggcggta 3261421 tccgataagc gaaattgccg ttttcaaagg ttaaaatgga ttcaattaat gtatcaatcc 3261481 ttgtcttcaa ccggttgccg tacatatacc ctgaggcgaa accgacggtc acgctgatca 3261541 gaagcaaaat caggataaac ggaattccga accagcttga tgacagcaaa acaagcggat 3261601 cgagccgata gtaaaacatc ataaaggaaa tcaggcaaac aaaaaggagc aggctgattc 3261661 ccgttgtcat gcggatggcg cgccattgga ggctggcaag catttttttt ctcatacgta 3261721 cttcacatcc acatcaccga taaataagga aacggacact tttacccggc gctttgactc 3261781 gctaaaatca gttgacgcgg catatacctt cgtgcttaat ccgcttttct tcgagccgat 3261841 cagattaatg tctcctataa aaacagccga gctgacagcc acttcaaggt ccgatggtac 3261901 ataaatatca acgttaccaa tgactccgct aatgacgatt gtactttctc cctcgggaat 3261961 catcgcttta gataaatcga ttttgatatc accgataaaa ccagagacat ttaaatcgtt 3262021 caggtcaaac ggctgcttca tcatttgcag ctcaccgata aaaaagctgc gcatgtcggg 3262081 atgttttaca tcttttggcg gctcatgatg ttctttttta ttgagattga cctgtttctc 3262141 attcggttca aatatcggct tccctttgat aagcctgtag ccggcgtaaa tcagaaatgc 3262201 ggcaaacgca tagccgaata aattaaaggt gatgctgaag aggtttttca aaaatagaaa 3262261 cgcggcaaag atatacatga cggagccaag ccaatcacgg gaatattttt taaggaaata 3262321 gccggcaatc agaaaaaaga gcggccaaaa cagcagatcg cctattccga taatttgcaa 3262381 aaacatactg atgccgaata aagcaatgat caatccgaga agctgttttt ttgtcattcc 3262441 tggtgtccgc ctcctttctt ctgcctagtg ctaccgtatc gctagatccc cgctgtccgt 3262501 tttgatgtcg attggatgcc ggccgcttcc ttgcgtgcct gtgatgtgat gctgttcttt 3262561 atgtccttta tcagcaaatg aatacggcga actgacgtca ccgcttgctg ataaagcatt 3262621 gactgcaaag ctgccatttt ggggaaggct tacattagca tcaccgcttg tcagcgtgac 3262681 agatacggga ccggttacct ttttcaatac agcattaaaa tctcctgaag tcattttcac 3262741 atcaagagag cctgatacat gaaccagatt tgcgtcccct gaagctaaat caatgccggc 3262801 tgttttggag acggtatttg aaatggaaac atcccccgat gatgccttca ctttcagatc 3262861 ttgaatgcgg acgtccgtca cgctcgtatt tccgctcgca gatactgcgt tcagcccgga 3262921 aagcgcaaga tggtcattcc cggccacaga cacgtcaccg cttgaggttc gtactgccag 3262981 atcaccttta taatcatacg gaagcctgac gataagagtt gaacggttaa atccattcaa 3263041 aaattgaaat tctttttcct ttacggtcag ctccagtttt cttttgtttt cagtaacaaa 3263101 taactttcct gagtctcctg aaatgcctgc cgatatgtca cttcgttctt ccgctataat 3263161 ccggacatcc ttgctatccg actcaatgac catgctgtca atgtcccgcg gcgatgcgct 3263221 ggctgaatca gcttctgtgc catttatgaa acctaggcct gcagcaaaca catcttttac 3263281 gacgacggcg aaaaaaacca gaataccggc agtgatcaac agtttgccaa gcattttttt 3263341 cattcggttt catccttctc attcattcta ttataaagga aaagcttgcg aattgatacg 3263401 tgcggaaggg aaggacttga ccgcaaatcc ttccccgttc cgcttattca tttgccgctt 3263461 ttgtctggtc tgatttttgc agtgaaagtg tccgcatttt ttcaatctcc gcttccacat 3263521 cgtctgcgaa ttctttacgt gtaagttctg tgccggcttc cgctgacttt gaataattcg 3263581 cgcggatttc catttcttca atacgatttt caatacgtaa aaattcacga tacgcgcttt 3263641 cactgtcaat tttgtcaaat gtcgtattca tatgctcttt agctttcgcc gcatttgccc 3263701 gcgcaatcag cgcctgtttt ttatccttta cgtcctgaag ctttgtttca agtgcagcca 3263761 gctgctcttt cagatcagcc agctgactgt ttgcctgttc ataggaagct ttatgctcag 3263821 ccgccttccc ttctaaatac ttcatttcag tcagcgcctt tttcgccagt tcttcttcac 3263881 ctgcgtcaaa tgcgagctgt gcctgatttt tccgtttgcc agccacttca gcggcttctt 3263941 catatttttt cttaaattga taggcaatcg tgtgctgttt cacaattgtt tgctttgctt 3264001 ttgcgatgtc gctttccata tcgcgtacat attgattcag catcaccttt ggattctcca 3264061 ttttatcaag tccttcatga actgacgcaa caaacatgtc tctgattctt tttaatacca 3264121 tacctgattc ctcctaatat attgatatta ttttttcttc aaaaattctt cccattcgtc 3264181 atcaaagtga gattggtagg cagcagaagc cggttcagga tcaaaagatg atacaccgtt 3264241 atcagctgat ccgtttttca tcagcttcca gccgtaatac accatagcgg ccgccaatgc 3264301 gattccgacg acaaacggaa gtgagcagat gagcataatg gctccgatac cgcccacgat 3264361 gattcccgtg atggtttttc ccgcggcaaa ccttttgatt cctgcgtatg tcatcaagct 3264421 cccgatggcg agcgggatga taaagccgaa gcttcctcct ccaaaaaaga cggagatccc 3264481 aaatacaatt aataagaatc cgcctattgt tttcttgttt attttcatgc agatcctcct 3264541 ttcgttttcc ttgtcttcat cttatacaag ttggaagata tgcaaaacga atcagagatt 3264601 gatttttata taagaccgga gtcgtatctc gcaccggacc cattggcaca aaaaaacgcc 3264661 atgcacgagg catggcgttt taaaaccctt tacagatgaa cacttgcttc cctttcttta 3264721 attaggtcgg acctttctgc tttggccaat tttgtaaaca gcaagattcc gatacccgca 3264781 ataatttcga caatcccacc gacagcgatc actttacctg agccgaaagc attagcggca 3264841 tacccgcaaa tgacagctcc ggcagggatc gaaatatttg agatcatatg tataacggcg 3264901 taaacctgcg gctgatcctc actatccaca gacgtctgga taatcgtgta ctcaggaaca 3264961 ttaacagcac tgactgcggc accaaaggta aaagcagcga aaaagacgag cggcaaaaag 3265021 gtattcatcc cggtaataaa gaaagcaaat ccttcaataa tgccggcagt gacgaataac 3265081 aagccgtacc tgtttacctt gactttcgcc agcacaaacc ctaataaaaa cgcgcccgcg 3265141 gcggtggtgg cctttaaaag cgagtatacg atcggctggc cgtttaaatc ttccgcaacg 3265201 tatacggcag agagcgcttc ccatggggca gccgcgaaat tcataaagat acagtaaatg 3265261 gcgagcggat ataaaatctg gtgttttctg acgagcctaa agccgcgttt cagtcttccg 3265321 atatatgtgc ctctctgtgt aacaaccgca gactctgatt gagattcaac cgcagtgtac 3265381 ttaataaaaa gaacgagaaa acctgacacc aaatagagca caagtgcgat aagcatggta 3265441 taagaaggac taataaatgt aagaaaagcg ccgcataatg tgacagcccc aagccggaca 3265501 atttgagcgg aggattgcag cacagcgttt gctttttgaa tgccctgttc attgacgatt 3265561 tgaggaatca aagcgataga ggcgggattg taggcagctc cagtagctga atgcacaatc 3265621 ataagcgtca tgacaaacca cagcggagag aagcccgcaa aatgacatag agggataatc 3265681 aaaacaatcg ccgcccttgt cagatctgaa aagtacatcc aaaatttcag cgtggtctgt 3265741 ttcataaaag gccccgtcac aggcgccaga acggcttccg gcaaaaacgt gacagcaatc 3265801 aataaagcag tgccgatcgc acctttgccg tcataaatta aaaaccataa tattgaatta 3265861 aatgcgaaca tatcgccgga tatcttgact attcttgaga aaaacagata attgaaattt 3265921 ctcttccaga tgctatcact ttcaattaaa ttcaccatcc atcagagccc cccgttgcct 3265981 attttttaca tctatttatt acaatatctc atttttccat ttttcagtca ataattcata 3266041 aggttcattt tttgtcgtaa aatgggaaat tgacagagtg aaaaacaaaa aaagccggca 3266101 tgtatttgaa cacgccggct ttccttttca ctttttatga ttcgctgctg tttcggtccc 3266161 gaaacacaat ggcacttctt tcatattcta catcgccaat accgcttctt gcattcacaa 3266221 cccgggcggc ggcaaagaaa taatcggaca gacgattgag ataacgcagc actgtttcat 3266281 gaatctcctc cgatttcatc agcgccacca ctcttcgttc tgcccgcctt gtaatggtgc 3266341 gtgcgatatg gagaagcgaa gcacactttg atccgcctgg aagaataaat ttcttcagtt 3266401 ccggcgcttc tgctgtatag gcatcaatgc gcgtttctaa aaaggaaaca gattcttccg 3266461 ttagtttata gtcttttctt tctgtgacga ttgccagatc gcctccgcag tcaaacagct 3266521 catgctggat ggtcagcagc tcggctgtca gatcttcaaa gccgggctgc ccggaaagct 3266581 ctgccaaagc aagcccgata aagctgttaa gctcgtcaat cgtgccgtag ctttcgacgc 3266641 gtaggctgtc cttgtccgtt ctgcccccga ctaagcccgt ttgtccctta tcgcctgttt 3266701 ttgtatatag tttcataccc tgaatctcct ttacagactt attcaaacaa ctcagcagcc 3266761 tcttttatac attcagctgt ccctttcttt atcaattggt tcagccgctg ttctatgttt 3266821 tctgattgct gagtttgagt cgcggcgatg agaatatcac ctgtgcctcc tccgtctccc 3266881 agcactttcg tccgttctgc ttcggcagcc ataagagctt tgatgaagaa ttgatctgcc 3266941 gcatagccgt taatcaaaat ccaaatcgaa aagccggtct gaacgcatat gaaaacggat 3267001 aactctccgt cttcatatgt tcgatacacg aaacggtcaa gtctttctga agaagccatc 3267061 gcacacgtct cctgcagttg aaaaccgctt tctgaaagac aggccgtaag tccttctatc 3267121 ggatctggct gatctggcag ccgtttatgg atcagcgtcc tgctccacga aaaccctgca 3267181 ccgataggcg tggaggacaa tgttcgaagc gggatttccg tttgcagaag aatgtcatca 3267241 cgccccgctt ggagcaatgc ttcaaatggg atagactgcc gcttcacgct atctttttca 3267301 ggctgaatca caatcatcgg tttaggtgag ctttgatgaa ccaaggcggt gacatctgta 3267361 tcgtacaccg cctttatgct ttgttctgta acagcatatt ccggtttttg cttaggcccg 3267421 gcggtaccgt ttttcataaa catgagccca tcacagtaca ggcttgcggt gttcagatca 3267481 tgaaaaacgc tgacagctgc caatccgctt tctctcgtca ggcgtttgat cagatcaagc 3267541 aggtcttttt gataagccag atcgagaaaa ttagtcggct cgtccaaaaa taaaatacgc 3267601 ggctgctgcg ccaaagcttg tgccaaatac acccgctgct gttcccctcc gcttagttcg 3267661 cgaatcggct tttgcgcaaa atcggccact cctgtttgct ccattgcttc ctgtacaatg 3267721 gcttcaccct tttcagtctg ctgtctgaac agccccgttt ggaatggata tctgccaaag 3267781 gctacagttt cttcgacagt aaaggtgaag gcttgatcca ttttttgcgg caggacagcc 3267841 atgatttgcg ccagttcctt cggtttatag tccgccagca gttttccggc cagataaacc 3267901 ctgcctttct tggccggcag cgtacctgtc agcaagtgca aaagcgtggt ttttccgctt 3267961 ccattagggc cgagaattcc aagaaattct cccttctcca ctgttaagct gacattgttg 3268021 attaggcggc tgtcgccgta tcctcccgac agcccttctg ccttcatcat aagcttctcc 3268081 ccccgcgatg ctgccgaatt aaaataagag cgaacacagg cgctcccgcc aaggacgtaa 3268141 tgatcccgat cggcagttca atcggctcaa tgatggttct ggaaagcaga tcggctaaaa 3268201 caagaaaccc tgccccaagc aaggcggaca acggcagtaa atgccgatgg tccgttcccc 3268261 acaaaagcct tgtgatatgc ggaatcacaa ggccgacaaa gccaatcgta cccgatactg 3268321 ccacagcgct tcccgtcaaa agagatccgg ctattaaaat catcatcttc ctctgctgaa 3268381 cgctgactcc aagaagcttt gctttatctt ctccatatgt catcacgttc agttcccttc 3268441 cgtttataat caataaaatg gttcccaaaa gaaaaaacgg gagaaacaaa ataacatagc 3268501 tccagcccct cattgagacg ctgccaagca gccaatgcac aatcggaagc aggttgtctc 3268561 ctgtcaaggc gatgataaga gaaataaatg cgcctaaaaa agagttggtg atgacaccgg 3268621 tcaaaatgag ggtggaaaca gacatcgaag catgaacgag gcggctgaag aaaaggaccg 3268681 ccgccatcgt ggccagtgcc gcggctacac tcaaaaccgg gagtgtaaac cctccgatga 3268741 caggaaggtg caaacctaag aacagagtca caacagctcc gactgaagca ccggatgaca 3268801 cacctagcgt atagggatca gcaagcggat ttttcaacaa tccttgaaaa gcggcccctg 3268861 caatagaaag agccgccccc acaagggcgg ccagcacaac tctcggcagt ctgatattca 3268921 tcataatatt agtgtacatc ggatcatcag aaccgataga gccgccgaaa ccttgatgcc 3268981 aaaagacacg aaaaacagcg ggaataggaa tatgcaggct gccgcaagaa attcctaaga 3269041 tgatgctcac ggctaaaaat gagaaaccaa tgatatatgc ggcataacga ttattcctta 3269101 aacgtatccg ggtaaatgct ttccgcaagt tcttcgaccc cttcgatcag acggggaccg 3269161 gaacgtgtca caagatcagg gtccacatca tatacacgat gatgtttcac agcattgatt 3269221 tcgctccagc catcgcgttt ttccacagct ttcgctttca caccgtccgt tgtaacaatt 3269281 gcatcaggat tgagttttac gatcgcctcg tctgtcattt gcacccatcc tgtctgatcc 3269341 gcagctgcgt ttttagcatg gatgacattt agcatttcat tcataaacgt atcttttccg 3269401 gttgtataaa tgtcaggatc aggagaaacc tcgataaata cgcttttctc ctcgtctttt 3269461 gaaatggttt tcgctttttc ttgaatatcc tttagatctg atttcatgct tttcacgagc 3269521 tgatcggctt ttttctccgc cccgccagct tctccgatca tttcgattga tttgtacacc 3269581 tcggagaatg attgtgcatc attgacagtc agcactgtaa tgcccgcgtc cttcagctgt 3269641 ttgatggcat ccgctgatgc tgacatggaa gactcatggg ccagaacgag atctggtttt 3269701 agagaaatga ctttttcaac gtttacattc atatctccga ctttctcaac ctttttgact 3269761 tcctttggat aggtatcgtt tgtggtgaca ccgaccactt tgtcaccaag gccgagtgcg 3269821 tatgtaattt ctgtgttgct cggcattaat gaaacaatct tttttggctc ttttttgatg 3269881 gttacatctt ggtttgacgc atcatcaatg gtgacaggga acacttctgt tttttgtttt 3269941 gcctttgaat ccttctgatc cgcaggattg ccgcagcctg ccagcataac agcagccaac 3270001 agaagcgcag cccatatccc ggctcgtttt ttcataatct tttcctccta aacgaactaa 3270061 aaaagcatct ctacgacggt aaagatgctg taaacaacac aaaaaagcct attgtttaca 3270121 catcatctgt cctcgcagaa ttcgtgctga tcaaacaggc aggtatcctg gctcttggcg 3270181 cttggccaat tacagtggcg ggaccgcacc ggcttttacc ggtttccctt ttaagccggc 3270241 tgttgttcac ggaccggcac ctatttgaca ttcgtatccg tttttcggag taattatact 3270301 atatgactga caggcttgta tatgtgtcct gaatgacttt tccccatatt gtgtatggaa 3270361 gcaaaatcct cgtaaacact aaatttgatc ttgtatactt aataccatca tctatcaaaa 3270421 ggaatgattc ttatggattt acagctaaaa gaaaaactcg tcttaatcac cggctcgacg 3270481 tccggtatcg ggaaagccgc cgcaaaaagc tttctgcaag agggtgcggc agtcattgtc 3270541 aacggacgca aacaggagac tgtcgatcgc accattgaag agctttctgg ctatggaaca 3270601 gtgcacggtg ctgctgccga tttgtcaaaa acagatgaag cagcggcttt tatcgaaaaa 3270661 gtaaatgaaa tcggtgatat cgatatcctt gtcaacaacc ttggtttctt cgaggtaaaa 3270721 gacttcgccg atgtgacaga tgaagagtgg aatcaatatt tcgaagtgaa cgtgatgagc 3270781 gccgttcgga caagccgtca cttccttcca aaaatgcttg ccaaaaacag cggccgcatt 3270841 ttaaatattg caagtgaagc aggcgtcaaa ccgctgccaa cgatgattcc atactcaatg 3270901 acaaaaacgg cactgatcag cctttcaaga ggaatggctg aaatgacaaa aggcacaaat 3270961 gtgacggtca actcagtgct cccgggacct acttggacag agggcgtggc ctcctatatg 3271021 gaaggcgccg cacaagcagc cggacaggat acagatacat ttatcaaaga ctatttcaag 3271081 gtcaatgagc caacctcact tattcagcga tacgcgacag cagaagaagt cgccaacaca 3271141 atcgtattcc tcgcgtctga cgccgcatcc gccattaacg gcacggcaca gcgtgtggaa 3271201 ggcggcatta tccgttctct gtagtataaa aaaacgcatc cgtgtttcgg atgcgttttt 3271261 tttatacgtc tccagcaaat ggtaccggct gatatccgcc tgtttccagt tgtgctgaaa 3271321 acaaccctcc agcgtgaggc tgctcgtatc tctctttttc tgtcatttgt tctgttgccg 3271381 ttgtaatgta aagggttttt aagtctctgc cgccgaacgc gcagcacgtg acatatttag 3271441 ccggcacgct gattgaattg atttcttttt tctgaaacgg gtcaatgtga acaacgcggc 3271501 tgccgccaaa cagcgccacc cacagcatgc cattttggtc aattgtcatg ccgtccggca 3271561 atccgtctga ctgatcaaaa cgatagacag gttctggatt cgaaacatct ccgctttgag 3271621 gatcatagct gtaacgtaca atctcctggg tcggcgtgtc gatgtaatac atcaaattcc 3271681 gctcgcggtc ccaatccaaa ccgtttgagg tggagacttg atccttgatt ttgacaagac 3271741 tgccgtctag attcaaacgg tacagcgacg cctgtttttg ctcgccttcc atgctcgtcg 3271801 tccccgccca aagccttccg tacgggtcac atttagcatc attaaatctc aggctctcat 3271861 gcatgtcctt cggctgttta attttttcca agctgtcatc ccgaagatga tacaggtaaa 3271921 acccgtcctt catcgtcata atcagttcat cctttgaata tttcgcaagc gccgtcacaa 3271981 aggatttgaa tttgattgat cggttgattt tttcttcagg gtcaaagatg tggagctcgc 3272041 tccccaggat atcaacccaa tataagcggc cgttctcttc atcccataac gggccttcac 3272101 caatcactgc ccgagtgtct gcttccaata ctgcatccat gtgttacacc tctttagctt 3272161 cagtctatat attgttattc ccggcaaaga ggtgtccaaa ccacttgatg tttattgttt 3272221 tttaaaaagg atggtaatga ccgttccaat gttcgttctg ctgttcacat ggatcgttcc 3272281 gttatgcaga tggacaagct ccttggcaat cgcgagcccg agacccgttc cggcagttga 3272341 atcttttgtg ttcgtccctc tgtagtagcg gttaaacaaa tgggtgatcg tttcttcatc 3272401 cattcctttc ccattgtcct tcacttttaa agaaatatga ttttttgttt gctccagaat 3272461 gacttgaatc tctgttcctt tgccgttgtg cttcacggca ttcccaagga ggttttctaa 3272521 tatgcgcctg aaccacgctt catcaagggc aaattcaata tgctcttctt tggatacaaa 3272581 cgagatatca tagccttcag aaaacggatt tttcttaaaa tcctcaatga catttttaaa 3272641 aaacgggata aggctagtga gctttctctc aataggaaga gcatcatttt tcaggcgata 3272701 cgttaaattt aagtcttcaa tcagcttaga catgtattca gatttttctc tgacaacctg 3272761 ccccatttct ttcacttctt ccggcgacca gtcatactgc ttcgactcga gcatcatgct 3272821 gtagccgtaa atgctgctga gcggtgtttt taagtcatgt gacaaaccgg caatccattc 3272881 ttcccttgtc gcctggattt tttctctgtt tcttttatcc cttctcagcg tttcagtcag 3272941 ctgatccatt gattcaaata tctcaccgaa gaagcggtac ggctgtttga tttttccctt 3273001 tttatttttg ctgacaggac ggccttcccg gtttctgggc tcctcaagct tcccttttga 3273061 cagattgacc agccatctaa tcgtgtgaaa aatcggcagc ccgaatcgga acatatacca 3273121 aacggtcatc caaatgatat acatgaacaa aacggccatc acgagaaaca tcgcttttaa 3273181 tacaaccttc aggaatgatt tgttaaactc ctgatcggtt acatagactg ggttcggcac 3273241 cgtagcgacc atccatctgt ctttattgag gatcttaacg gaaatttccc gcttatagtt 3273301 ccaaggctta gagctgtatt taagcagctc cagctggttc atcgtttttc tctcgctttt 3273361 tgtgctgttg atgctgtcga gaatctttcc attgctgtct aacaggtaaa tggcgccttt 3273421 tttccgttta atatagtcga tggtactaga cttatagtgc gctagtgagt ctatcttttg 3273481 ttcacgcttt tcaacggaag tcaggagctg ttcacttttt gatttccagc cggacaatag 3273541 aagatacgac ttatcttcaa tattgatggc ccaataattc agtttatagt tatgaagctt 3273601 tttggtttta taaatagaca aaagctcttt cttggtatag gtgcccggca cgtcttttgg 3273661 cacgccgtag gaataatcag tgtttccttc cgaatcaatg atttgcatcc agccgtgctg 3273721 tttatcaaca gatttcttca ggaaattatc cacttcccat gtcccgtctt cgtttacatc 3273781 gagatatgcc tcaagtgtgt cggtcgttgc tttcgtcagc cctgaattgg attccgcatc 3273841 gctaaaacgg gcgtctaaat agaaaaacga tgcaacaagc ataaccgtaa gcagcaggat 3273901 cacaatcagc atctggccga aaaagtgaaa caaaaacttc catcttaacc tcatgaccgc 3273961 ttgccttcag gatttgggat aaaacgatag ccgagacctc gaacggttac aatatactcc 3274021 ggattgctcg gatcgcgctc aatcttctcc ctaagcttgc gaatatgaac catgacggtg 3274081 ttgttgtcac cgtaggaagg atagccccat actttttcat atatttgatc tttggaaagc 3274141 accacgttag ggtgttcaca aaaatactgc aaaagctgca gaagctgggc tgaacaggca 3274201 acggcttccc cgcctacgat caactcggca ttttgcggag aaaaagtaaa gtaatcatat 3274261 gtgtaggttt gatttgaact cgtttctttc gattgatatg tacgcttgag atgcgctctg 3274321 atccgcgccg ctaattccag cggattaaat ggttttgtga tatagtcatc agctccaacc 3274381 gcaaagcccg ataatttgtc cgcgtcggat gatcttgccg tcaggaaaaa aatcggagcg 3274441 tctgaatact ctctgatcaa tgtgcaggct tcaaaaccgg acattccgcc catcatgaca 3274501 tccagcacaa tcaagtcaac cttattggcc ttcacaacgg gaatcgcttc ttctgcgctt 3274561 gccgcatcca gtatatttcg ataaccttct ttttcgagaa cgcgtttgat catgtccaca 3274621 atcgctttct catcgtctac gattaaaatt gacgcatttt ccacttttat gttcctttct 3274681 gtcactgttt ttttcatctt atcattatat cgtttattta tggtacattt ttgaatacat 3274741 tggagccttg gcaaatcaaa acagcaaaaa aggagcaaac aagcgctccc ttttgatgtt 3274801 ttttcatatg aaaatattat gagttctcat ctaccatgta caaaataaac tcccaaaacc 3274861 ccggtacatc ctgacataaa agcatatcag ccttttcaaa cattttgatc ttcagctctt 3274921 gctctaaatc ttctctttct tgataggacg tattgctgag tttttttctg atcatcggtg 3274981 aaaagcatgc aatcaggtgc tcaatgtcat aagtctcgtc tttttgtttc tttttttgtt 3275041 caaactggcc gtccacagct tacttttccc cctttttttg cgccgctaac tgctttctga 3275101 tattctccag ccccttttta tgaatgttgg agatgttttg tcgggactcc cctaatgaat 3275161 ctgcaatctc ctgcatcgtg gcaccgtgaa gatagacttt cgtcagcaca cttttttgtt 3275221 tgtcagtcag cttctggatc gcttggtaga gctggtaatc ctgtacatgc tggctcaaat 3275281 catcctgcct gtctaaaaat tcttcaaatg catcgctacc tgtttcggaa gaaagccgat 3275341 ctcccgcctc cggatgatca accgtcagtg gataccgttt ttggtttttg cgaacccgct 3275401 tatcaaaatc aatagaaaag atgcgaatca ttgaattcat atacttgacg atgcggattt 3275461 ctttataaaa ttgcttaaat agctcgtcca atgatcttgc atctttttcg ttagggcttt 3275521 ccattacgtt tttgaacaaa cggtaatgct gaggattgct caaaaaatgc ttcacgatgg 3275581 gatgcttcat tatctcctta cattttgacc gtaaaagact ttgatagtcc atcaaaccgc 3275641 ctccctacta aattaaatga aggaaagcaa aaaaaagtaa actactactt tccgcctagt 3275701 gtcttccaaa atactttgca gcagtttacg ttttatcggt tttcctcact tacatacatg 3275761 actgcagaaa aagaagggag gtattttcct atggatcagg tttttataga ggaagtcgta 3275821 aaacagatcg gcaatttggg gtttcccgcg ctgattgcaa tgtatctgct gacccgattc 3275881 gaaaagaagt ttgatcaact aatagaacta atgacagaac tgaaagatca tgcaaaaaaa 3275941 taatttttca atcgaagttg acttttcact ggtttttttc acttaacaaa acagaaggga 3276001 aaacgaaagg cctttcacct tctctttctg ctatcacatt taaatgtaag gaggaaacat 3276061 ttcatgaaaa aacaaaatga cattccgcag ccaattagag gagacaaagg agcaacggta 3276121 aaaatcccgc gcaatattga aagagaccgg caaaaccctg atatgctcgt tccgcctgaa 3276181 accgatcatg gcaccgtcag caatatgaag ttttcattct ctgatactca taaccgatta 3276241 gaaaaaggcg gatatgcccg ggaagtgaca gtacgtgaat tgccgatttc agaaaacctt 3276301 gcatccgtaa atatgcggct gaagccaggc gcgattcgcg agcttcactg gcataaagaa 3276361 gctgaatggg cttatatgat ttacggaagt gcaagagtca caattgtaga tgaaaaaggg 3276421 cgcagcttta ttgacgatgt aggtgaagga gacctttggt acttcccgtc aggcctgccg 3276481 cactccatcc aagcgctgga ggagggagct gagttcctgc tcgtgtttga cgatggatca 3276541 ttctctgaaa acagcacgtt ccagctgaca gattggctgg cccacactcc aaaagaagtc 3276601 attgctgcga acttcggcgt gacaaaagaa gagatttcca atttgcctgg caaagaaaaa 3276661 tatatatttg aaaaccaact tcctggcagt ttaaaagatg atattgtgga agggccgaat 3276721 ggcgaagtgc cttatccatt tacttaccgc cttcttgaac aagagccgat cgaatctgag 3276781 ggaggaaaag tatacattgc agattcgaca aacttcaaag tgtctaaaac catcgcatca 3276841 gcgctcgtaa cagtagaacc cggcgccatg agagaactgc actggcaccc gaatacccac 3276901 gaatggcaat actacatctc cggtaaagct agaatgaccg tttttgcatc tgacggccat 3276961 gccagaacgt ttaattacca agccggtgat gtcggatatg taccatttgc aatgggtcat 3277021 tacgttgaaa acatcgggga tgaaccgctt gtctttttag aaatcttcaa agacgaccat 3277081 tatgctgatg tatctttaaa ccaatggctt gccatgcttc ctgaaacatt tgttcaagcg 3277141 caccttgact tgggcaaaga ctttactgat gtgctttcaa aagaaaagca cccagtagtg 3277201 aaaaagaaat gcagtaaata aaagacttgc ggcttgcaga gagcactcgt tctctgcaag 3277261 ccttcataag gagctgaacc agtgaaacat caaaaccctt caaaacgctt attgcggctc 3277321 tccataaagt acttgctggc cgcagcagca gtggtgttga cctattttgc tgtcatctat 3277381 atattgtttt ctttagcggg aacgagctac cgctcagcag ctcatgtcct gctttttgcc 3277441 gtggtattcc ttgttctcgg attatgcttt gaaccatttg aacggctgat gatacatagc 3277501 tttacatttt tcaagacagg aaaacgtcta ttcattctcc ttgctggcat cgtacagctg 3277561 ctgtttttgt ggatgactgc tcatacaaca gaccaattga tcagcgacat ctggctgtcc 3277621 accacagaag aaatgattgt cgcagccgtt tttttgattt tagacaaatg caactcggct 3277681 cttcccagct aaaaaaagaa cgcattccaa ttggatgcgt tctttttatt catagcgaag 3277741 cgcgtctaca ggctgaagct tcgaagcctt gatagacgga agcaagccga agataatgcc 3277801 gactgccatt gaaaagatga gtgctccgac aacagctgga atggagacga taaaaggcat 3277861 cggaaaaatg accgtcagca gcttggcgat gccgaagccc gccagcacac cgagtattcc 3277921 gccaatgctt gtcagcacga cagcctcggt taaaaattga aataaaatca cacgccgctt 3277981 agcaccgagc gctttcttaa ttccgatttc cctcgtgcgc tccgttacgg aaacgagcat 3278041 aatgttcatg acgccgatac cgcccaccaa aagtgaaata ctggcgatac cgccaagcag 3278101 caatgcaaat gactgattaa aggactccac ttcctgcgcg atctcctgaa gatccattac 3278161 actgtactct gctttttcca gctcagcttc tgacagtccc tgatttaaaa gatctgcagc 3278221 cattacaccc gcttcttgga tatgctcaga agaatcagcc tgcacggcaa tctgcgttgg 3278281 cgcgtcaaat ccttcaataa gcggccacac ttttttcggc acgtacaaaa ccgggttcgc 3278341 atagtcgcct tcaaacatgc tttcctgttg atttttttct ttaaaaacac ccacgacctt 3278401 aaacggcaca ccattcatct caatgctttt atgcagagct tctccgtctg gaaacagttc 3278461 atctctgaca gcttcattga tcatcactac ttggtgtgtg ctgtttaaat cgttttccgt 3278521 cagctttctc ccttcggtta ttcggattgg aaacatgtcg aagtaatcat cgtccactcc 3278581 atacacttgg ggatacgaaa cgttagttaa atgaaaaacg ctcgcgcctt ctgacaagta 3278641 atataaggat aatcctttga ccatcggatc tgatttgatc gcctttactg tttcttccgc 3278701 tacaggcggc gcggacgcat acgacacctg agggccgccg ctctcctctt ctccgccaga 3278761 cggctggtag acaacattga tggcgttgtt tcccatgccg atcatacttt gctttaactg 3278821 ctcactttgg cccttcagca ttgaaacaat cgcgatgatt gccgctatgc cgataatgac 3278881 gccaagcatt gtcagaatcg atcttaattt atgagagaaa atggattgaa aggagattcg 3278941 aatatgttca agcatggctg atatcccctc tctcatctaa taccaactct ccgtctctga 3279001 taaaaacggt tctgtcagct tttttggcga cgtccgggtc gtgggttatc ataataatgg 3279061 tcttgccttc ccgatgcagt tcagaaaaca gtgccaaaat ttgttcactt gatttggtat 3279121 caagcgcccc ggtcggttca tcagctaaaa taaacctcgg ctgattgaca agggccctcg 3279181 ctatcgccac ccgctgcttt tggccgccgg acagcttagg cggtttgtag gagaccctgt 3279241 cttttaatcc gactttttcc agcgcttcat atgcccgttg ccttctctct tttttcttca 3279301 ctttattgta gatcatcggc agctcgacat tttgcagcgc ggtgagacgc ggcagcaaat 3279361 gaaaagtttg aaacacaaac ccgattgatt cattgcgaat ttcggctaaa gccccgtctt 3279421 tccctttcaa tatatcgatc tggtcaagcg tataggttcc tgaggttggc ctgtccaaac 3279481 agccgataat attcattaac gttgactttc cagaaccgga aggccccata atagctaaaa 3279541 actcccccgc ctgaacggtc agattgatat gtttcaagat tggaacttct tcttttccca 3279601 gcttgtacga cttcgaaata ttattcagtg tcagcattga ctgtaacctg ctttccttcc 3279661 ttgaccgcgg gatcaggata gatcacataa tcttccggcg tcaggccgct cttaatttcc 3279721 accatgtcat tttcatcagt ctctccgatt tcaacaggct gcttaaccgc tttgtgattc 3279781 tcatcagctt tccatacgta cggttcgccg tcatcctgaa tgaccatgtc ggacggcagc 3279841 ttgatcgtgt ccgcatcagc attatcactc atcacttcga tgttgacatg atagccgact 3279901 tcaagacctt tatggctgtc taataaaatg gtgaaaggat agttagagga ctggggattc 3279961 atttcttcat cagcaaagct ttctgattct tcaccctcgc ctgctcccgc tggaagcttg 3280021 ccgatcgagg tgacctttcc tttccactcg ccctcaccgc ctgttttcag cgtgaccctg 3280081 actttgctgc cttttttgat cgtgtccatt aacagctcat tgatttggct tttgaccaga 3280141 tatttgcctg tcgaaacaat ctggatatac gggcctgctg cctggtcgcc tgttgcaccg 3280201 tcagcgatat cctgattgac gctttgaacg attccgtcat gcttgcttgt aatgacattg 3280261 gaacctttgt ttttcgtcag gccagccagt tctttttgat gctgcttcag ttcaagctgg 3280321 cttgttttca aatcgaaatt ggtttgatca agttcatctt gaagctggtt tttctcttct 3280381 tttcctgcaa ctttcagctt tttttccgtt tccgttattg atttttgcaa acggttgatt 3280441 tgcagatttg tcatttcaat ttgcaaattg gcttgctcca cttcatcaga atgatcctcg 3280501 ccctcatact caaaaagctt atcgcccttt ttaacctgat cgccttcttt gacgtatgtt 3280561 tttttaatgc tgcctttttc tgaatctatg tatactttct gctgtttctc aggttcaacc 3280621 tttccagaaa acgtttggcc tgattctgaa tctcctccca tgtataccgc gaccgattca 3280681 gcatagggct ccgatgatac ggcaacttgg ttcatgtgag taaaaaagta aaaaccgcca 3280741 gcgccgatcc cagccaatac aagcacaccg gcacatatcg caccgccaat aagccatttt 3280801 ttcttcttgg acacaacgat ctcctctttc tgtaaactat gtaatatttt cgaaacattc 3280861 taaccaatat tatctattaa ttcaaaaaga cttgcaatcc ttttattgaa atgacggaat 3280921 caaatagaaa aattgtattt tcaaagccga ataaaaaaaa tcccggcttc aaaccgggat 3280981 tttttcatac agtaactagc tctttttcat ttttaatcaa gtcatatgtc aagcatacag 3281041 gtttatttgt acggggatca gtcacgattt cggcatcaat ctgaaatacc tgcttcaaaa 3281101 tgtctggtgt catgacctcc agagcagttc cttccttgat gaccgtgcct tttttgagcg 3281161 cgatcatata atgagaaaaa cgagctgcat ggttaagatc atgaatgacc attaaaatcg 3281221 tccgcccttg ctctttgttg agtctgtcaa gcagctgcag aatttcaagc tgatgtgcaa 3281281 gatcaagata cgttgtaggt tcatccagca gaagcagttc cgtcccttgc gcaagcgcca 3281341 tggcaatcca cacacgttga cgctgtccgc ctgacaatgc ctcaatcggc cgttcagcat 3281401 attcagccat gcctgtttct tcaagcgccc atttgataat ccggcggtct tcgtcattta 3281461 atctgccgaa tcctgattga tgcggaaacc tgccgtacga caccaattcg tgcactgtta 3281521 ggccgctcgg cgcttcaggt gtctgtggaa gaatcgccat atcttttgca atgtcctttg 3281581 tagacatttt atgaatcgct ttgccgttta aatagacggc acctgcatgt gaacgcataa 3281641 ttctggacat tgtttttaaa atcgttgatt tcccgcagcc gttcgggcca attaaggtgg 3281701 taattttccc tttaggaatc gatatattta aatcctctac aatcaccctg tcgccataac 3281761 cgattccaag ctgttccgtt gataatgaat tcatattcgg ccccctcctc taattcgctt 3281821 tcatcaataa ataaataaag taaggcgcac ctagcacgga aatgacaagt ccgaccggaa 3281881 tttctgatgg tgccaataca tttctcgcca gcgtatcagc aagcaaaaac aggaatgagc 3281941 cgatgaaggc ggagaccggt atcagcgtct ggtgacgtgg accggtcagc cttctagcca 3282001 catgcggcgc gatcaatccg agaaacgcaa tgccccccgc agctgccacg catgaagcgg 3282061 caagagtgac cgctgccaga agaagaatcc gtctttcctt ttcaacagcg gtgcccagcc 3282121 cggtcgccaa ttggtctccg agctgcataa tgttcaaata gcgtgcctta tataaagtaa 3282181 acagaagcaa gatcacaatc caagggagaa tcgcccagat catattccag ttcgcccccc 3282241 atattgagcc ggatatccaa accgcggctt gcataaaatc atgagggtcc atcttgagct 3282301 gaaaaatcag caacagggcg ttgaatccgg cattcacccc tatgccgact aaaatcagcc 3282361 gaatcggtgt cacgcctttt ttccatgcca gaatataaat gagaaacgca gcgaggattg 3282421 ctcctgccaa agcactgaac ggcagcataa atgttccgaa aaagctaaga tctgaagctg 3282481 acccttgaaa aaagtatata aaaagcacta cagcaagtga accgccggcg ttaattccga 3282541 gaataccagg ctcggcaagt tcattttgag acacgctttg caaaatggct ccagctacgg 3282601 agatccctgc tccaacaagc aaagaaagga tgatccgggg cagcctgaac tcaaataaga 3282661 caagttcatc acgcgccgtt ccttggccga aaaagacctg aagcgtttta agcggtgcaa 3282721 ttttgataac gcccaaattg agactgataa aaaagaccac cacgataagc aaaaaggtca 3282781 cagccattac aatgagcggt ttgtttgttt ttgttttcat tacagccctc tcctttcacg 3282841 acgtgccaaa taaaagaaaa agggaacgcc gataagagaa gtcagcgcgc cgacaggcgt 3282901 ttcaaagggc gcatttacga gtctggccgc tatgtcagca aaaacaagca aaacagcacc 3282961 gagcaccgcc gagcaaggaa tgatccaccg ataatccaca ccgaccaaaa aacgggtaat 3283021 atgcggaatg atcagcccga taaatgcaat ggtgccggca atggaaaccg cagctccggt 3283081 cagaattact acaataagca tgccaaccag tttcaccgct gatgtatatt gtccaagccc 3283141 ttttgccaga tcgtcaccga gacttaacac tgtaacagac cgggcgatga aaaacgcgag 3283201 cgttaaaccg acagcccctg caataagcaa aagctggacc cccgaccatt tcacacccgc 3283261 taccccgcct gcgtaccaaa agctgatatc ctgagcgaca tcaaagcgga ttgcaatggc 3283321 agttgaaatg ccggtaaaga aataagtaac tgccgtaccc gccagagcaa gctttacagg 3283381 cgtaagtccg ccccttgaaa acatgcctat gcccattacc gtcgatgccc ccagccccgc 3283441 tcccgcaaag gaccatagca caagccccat tgcagaaagt ccgggaaaaa aggcaaacgc 3283501 aatcgaaacc gcaaacgcag agcctgatgt cacacccata atcgaaggct ctgccaaagg 3283561 gtttctcgtc atcccctgca tgattgctcc cgacactgcc aacaatgcgc ctacaagcgc 3283621 ggcagccgcc gttctcggaa gccgaagatc atgtataatt tggtgagatg tctttgtcgg 3283681 ctgataatga aaaatggcct cccatacagt gcgcaaatga atatccgctg cacctaggga 3283741 tatggataaa aatgcgccaa ggcaaagcag gcatagacct gcgataagga cgatgaccgc 3283801 gccatatgtc cttgacgtcc attggatttc ttctgatgca gtccgtatat ttttatgttg 3283861 actcaactgc cgtacttcct ttctgttact gataatgatt atcaattgct gtttcagtat 3283921 atcacttttt tcagctgatt taatagagtg ttttgaacaa aaatgaaaat gcatttgcaa 3283981 aaatatcgtg tcaaccggca cttgcagtgg tataatcaca gatgataatg attctctttt 3284041 tcatctatct tttagaaaga aggtatgaga tatgacccat atatacaaga aactcggagc 3284101 cgcgtttttt gccctgttat tgattgcagc gctggcagcc tgcgggaata actcagaaag 3284161 caaaggttct gcctctgatt caaaaggcgc agaaaccttt acatacaagg ctgaaaacgg 3284221 aaatgtaaaa atcccgaagc atcctaaacg ggtggttgtc atggcagacg gctattacgg 3284281 ctacttcaaa acactcggca tcaacgttgt aggtgcgcct gagaatgtat ttaaaaaccc 3284341 ttactacaaa ggaaaaacca acggcgtcga aaacatcgga gacggcactt cggttgaaaa 3284401 ggtcattgat ttgaaccctg acctgattat cgtctggaca acacagggcg ctgatattaa 3284461 aaagcttgaa aaaattgcgc cgactgtcgc agtaaaatac gataagctcg acaacatcga 3284521 acagctgaaa gaatttgcaa aaatgacggg aactgaagat aaagctgaaa aatggctggc 3284581 caagtgggat aaaaaagttg cggccgctaa aacaaaaatc aaaaaagcgg tcggtgacaa 3284641 aaccatttcc attatgcaaa cgaacggaaa agacatttac gtatttggta aagactttgg 3284701 aagaggcgga agcatcattt acaaagacct cggcctgcag gctacaaagc tgacaaaaga 3284761 aaaagccatt gaccaggggc caggttatac aagtatttca ttagagaagc tccctgactt 3284821 cgccggagat tacattttcg cgggcccatg gcaatcaggc ggtgatgatg gcggcgtttt 3284881 tgaaagctcc atttggaaga acctgaatgc cgttaaaaat ggccatgtat acaagatgga 3284941 tccgatcgga ttctatttca cagacccgat ttcattagaa ggacaactgg agtttattac 3285001 ggaaagcttg actaaataaa caaaagagcc gcctgcccgc ggctcttttg cttatttata 3285061 aggaacggct caatttgaat catatcggat attttctttg agccattcat attaagctgc 3285121 atcctcatca cgatcagttt ttttatgctg gagagactga aaaacgtttt ttgcatattt 3285181 aacgaacgga ttcctaacag gagaaattgt gattttataa aaaagacacc tgagcaaatc 3285241 aggtgtcttt tcattatgct tgtttttctt tctggaactt gttactcaca aatggataaa 3285301 cgattaagcc gacaaagaat aaaccgatgc cgagtataaa tgtcgttaaa tctgctgtgc 3285361 ctgttacgat aacaaacacg gagtatgcac acgccagtat cgcgatcaat ccgtctctta 3285421 cacgggagcc tttcagctgg tcatacgttt cacctttgat gactaccttc aagctgtaga 3285481 ttgcagatac cagatacgga attaaatatg cgagtgtagc cgctgtcgtt aaaaatgtaa 3285541 atgcgtcact tattgtccgg gaaataaccg agaaaatgaa gacctgtgac atgacgtttg 3285601 taataatgag tgcaatgacc ggacttccct ttttattcgt ttttgcaaaa aatgccggga 3285661 aatctcctgc tttagcggct tggtatggca cctcagagcc aagcaaaatc cagccgagca 3285721 tcgttccgaa taaacaaagg atagccaaaa gcgccataat cacgcttccc gcgtttccaa 3285781 caatcgcata gagtacatca acaaatggtt tttcagagcc gacaagctta tcatgcggca 3285841 gaacacccat cgtaattaaa gtcacaataa tatatatgct caaggcaatc agcaagccgg 3285901 taattgtcgc acgtttcaca tcacgctgag agcgcgcacg gccggacagg atcaccgcgg 3285961 attcaattcc gacaaacgcc cacagtgtag aaatcgcagc gttatgaacc tggccaccaa 3286021 ttccaatgct tgtgccgttt tctccttgaa ccgggaaata aaaatgaccg aataatgacg 3286081 tttgaaacac aaacaaaccg gcaacgataa agaagacaaa acctaatact ttagaaagcg 3286141 ttgtgacaaa gtttaattta cttgcgccgt taatgctggc aacaagaatc gcgtgcgttc 3286201 cccataacaa gatcgtacat acggcaaacg tcagtaattg gccgagtgtc acctcttgcc 3286261 cgccgatcga aaacatctca cgtttatcaa ccaagatcgg gaagaacgaa gtcaagtaac 3286321 cggcgagact tgtgatgatc gccacgttac tgatccagct cgccacccag tagccccaca 3286381 ccattgtgaa accggcagcg ttgccttttt tcgggtcaga aaacagcgct cttgcataac 3286441 tttgcggtcc cgctgtcagt tcaggcttgc gaatggacaa gtgtccgaac acaagtgcaa 3286501 tcatcagcac gccggcacct gtcaaaagcc aggcggacgt agctccaaac ggactcgcaa 3286561 ttgaagcaag cgagctcggc aaggagaaaa ttcctgatcc aaccatattt ccaacgacaa 3286621 acgccgttaa taaccaaaaa ccccattttt ttgtctgttc cattccagta cctccatgat 3286681 tctttgtacg gaccagaccc cgagatcata taaacgcaaa aaaagcctga acaaaagtcc 3286741 atgcttaaag aaacacacac ccttgatctc cggatagccc tccgcgaaaa agcacgcggc 3286801 agtcctgcac ttattcagat acagtcccag catagagaag gatcggcttt ctccacactt 3286861 cggcgctgat gccttttaca catgtttaac agcccctgtc agcctagcat gtgtgactca 3286921 tcatccgcgc aacctctacc tcactgagaa agagtgagga tttaattatt cagttactcc 3286981 cagaaggtta tcaaagaaag gatgatctgt caaagggaac agatggaaaa tacggataga 3287041 gccaagccct atccgcatgt ggttatcgat tatttttctt tttttgcaca gcttcttgaa 3287101 gcggatcatc ttttagagct gaaccagcat cttcaagagc tccttggatt acgttttttt 3287161 ctttttcgga acgttttcct ttatctttat taaagaaacc cattcgtatc acctctttta 3287221 aaaaataggt acatgtttaa gatgcctttt tcctgaaaaa ttatgcggga tattttttat 3287281 cgtccaaagt cctgttgatc aaacatacat tctcttgata tatttgtaat tcagagattt 3287341 tttgcaaaag ataaaaggag aagcggcaaa tgacaggaaa aacacacatc atgggaggca 3287401 tcgcttcttg tacggcagcg gcttattatt atggatttga tccagtgctt atggctgcgt 3287461 caggcgcggt tggagcatta atacccgata tctgccacac acaaagcaaa atcgggagaa 3287521 aatttcctat tttatcgaaa gtggtcagct ccgtttttgg ccatcgcacc tttacacaca 3287581 gcctgctgtt tatgctcatc atgtttttta tcacttctac atacattcca gataaaaaca 3287641 tatcagccgg cctgatgatc ggaatggcga gccacttgat tcttgacgct tggacggtga 3287701 acggaatcaa attattattc ccttccacga tccgcgttcg gcttccatta tatatgaaga 3287761 caggcagttt ttctgagcag ctcgtgctag ccggcctgac ccttgcttca tgttactact 3287821 tttatatgct gtttcatggc cgcatgtttt aaacatgagt gctgagactt gtctgaaccg 3287881 gctgttttta gtaggtttta cttaagaagc atttcatgca gatgatcaag aaaacgtgag 3287941 gagtcatatt gatgaaagga accttttttc acaatcagcg gtttttatgt ttttcgatct 3288001 tatttatgtg gatcaaaacg tatgtgatat ataaactcgg ctttgatttg caaatcgata 3288061 ctctgttgga ggagctaatg ctgctggtca acccgctcag ctttattctt cctttattcg 3288121 ggatcggcct gtttctaaaa gaaaacaagc agcgggcctt tttgctgatt gccaatttgg 3288181 ttctgactgt tatcttgatc tctaatacga ttttttacgg cttttatatc gattttatta 3288241 ccatcccggt tttatttcag gccagcaaca tgagcgatat gggcagcagt gtaaaagaac 3288301 tgttccatcc tctgtttatc gccctgtttg tggatttggt ttttctgctg ttgttcgcca 3288361 gaaaaaccaa acacccacag acaaaagccg ctccccacac gatcaaacgg tactatgcag 3288421 cttcctgcgg aatgctttta tgcacactgg cacttgcaga agtacagcag ccgaagcttt 3288481 tggcacattc ttttgaccgg gaaatgctag tcaaaagcat cggcctgttt cagttccata 3288541 tttacgatac aatttctcag actgttaata tcagcgcgaa agcttttgcc gatgaagaca 3288601 gtataactgc cattaaaaac tacacagagg ctgattacag caagcctgat caaagcaaat 3288661 tcggtcttgc aaaggggcgc aatgtcatct ttgtaacact tgagtcgacc caaagctttg 3288721 ttctgaatga aaaagtaaat ggaaaagaaa ttaccccatt tatgaatgat ctcataaaaa 3288781 aaagctattc ctttgatcat ttctatcagc aaacagaaca aggcaaaaca tcagattcag 3288841 aatttatcgt cgctaactca ctgtatccct cccttagcgg cgccgtcttt ttcacgaaaa 3288901 gcgaccatca atttcatacg atgtataaat cgctgaagca gcacgattat tattcagccg 3288961 tctttcacgc taaccataaa acattttgga acagagatgt catgtacgat acatttggca 3289021 ttgaccgctt ttttgatgtt gatgattttc atgtcactcc cgggacatcg acaagctggg 3289081 gcttaaaaga caaagaattt ttagagcagt ccgccaaaaa gctgaaaagc ctaccgcagc 3289141 cgttctacag cagttttatc acgttaacga atcattttcc gtttgagatt gatgaaaagg 3289201 atcagctgat agatgaattc gattcaagca gtgatctgtt aaaccgctat gtgaccacgg 3289261 ttcgctatga ggatgaagca ttgaagcatt ttatcaaaaa actgaaggac gaaggcttat 3289321 acgaaaattc gatgatcgta tttatgggag atcattacgg catttctgaa gcccataacg 3289381 aggcaatggc tgagttttta gggaaagacg aaatcacacc gtatgacaac gttcagctcc 3289441 agcgggtgcc gtttatcata catatcccgg gaatcaccga tcaacagccg gaaaccatcc 3289501 ctgatgccgg gggacaggtc gacgtcaggc cgacgctgat gcatttgctc ggcgttgaga 3289561 caaaaggcga tatccaattc ggcaatgatt tgctgtcggg cgaccgcacc ccattcgccg 3289621 ttctgcgaaa cggcagcttt attacgaacg attatgtata cacaaagaac acgtgctata 3289681 gccaaaaaac aggtgaagtg ctggaagatc aggatgcgtg cctcccttac aaggagaaag 3289741 caaacgaaga actgtctctc tctgataaaa ttttaaatgg tgacctgctc aggttttccg 3289801 aatgaaaaaa tccctctatc aagagggatt ttttacgttt ccaatatcac cttgccagtc 3289861 agcttcgttt catagccgtt taaatgagac agattcgcct tgtagtcctc agaattcaaa 3289921 atctccttca cggctttgag caactgctca ttttttttca aaacaacgat atcatattgt 3289981 tcgtcgatga gcgggataaa atcaacactg cccatatgtg ccgcgtgctg tgccccgatt 3290041 cccgcgtcag cctgtccgct tgaaacttgt gaagcggcag cgtaatgatc agtcacgata 3290101 tcgccatatc ccactacatc agccggattc acaccaagca agccaagctg ttcatcaagg 3290161 agcacccttg cgccagaacc cttttccctg ttgatgatcc ggatatcggc tcttttcaag 3290221 tctttccagc cttgaatgtt tttcggattc cctttttgca catacagtcc tgctttgcgg 3290281 agaacgacat tgatgagaca aaacggttca cctgtcaaaa tccgttttac ataaggcgcg 3290341 ttatactggc ccgtttctgc atcgtacaaa tggaggctga caatgtcaca cttgccttga 3290401 tacatatcaa tcaggctgtt taagcttcct ttgtatttac ggagcggcgt ctcctgaatg 3290461 gcattctcca aatgcttgct gaggatatcc atcgaaatgt cctgtccgct gatcatgaca 3290521 tttggtctgc cgtccggctc agcctcctgc acctgtttcg gcgcttcttt tgcagcgatg 3290581 ggctgagaca ttctcatatt cgttttatat tgctttaaat cttcttcatc cacacgcatc 3290641 tgccttccga cacggtaagc aggcagcacg ccttttttaa tcaagtcata aacggtcagc 3290701 tttgatacct tcagcagacc tgcaacttct tctatcgtat aggaagaggt ttcattcatc 3290761 atcatcactc tcctatttta ttataccttt tcgccgaatg taaaaaaacc cacataaacc 3290821 aaacataatc agttataatt agttatatct aatgataagg ggtgcaatca tgtttaagaa 3290881 gtattctatt ttcatcgcag ccttaactgc ttttctgctt gtagcaggct gttcttcaaa 3290941 ccagtcttca acggacagcg agaaaaaagt aacgttaacc atctcagctg ccgccagcgc 3291001 gcaggatgca cttgaggaaa tccaaaaaaa ttatgaaaaa gatcatcaac atataaccat 3291061 ccaagataac tatggctcat ccggcgcctt gcaaaaacag atttctcaag gagcaggagc 3291121 agatctgttc ttctcagctg ctgaggataa atttaaaaag ctggtggatg atggagatat 3291181 cgcaaaaaaa gacagcactg aattagtcgg taatgaaatt gtgctggtcg taccgaaaaa 3291241 cggagattca cctgtgacaa gcttcagcaa tctggctgaa tcagaaaaaa tcgctcttgg 3291301 cactccggaa tccgtaccgg caggagctta tgggaaagaa tcactgacaa agctgtcttt 3291361 atgggacaaa gtgaaggata aaattgtgta tggaaaagac gttcgccaag ttctttctta 3291421 tgttgaaacc ggcaatgtag acgcaggtgt tgtttataaa acagatgccc tagtctcgaa 3291481 aaaggtcaac attgttgacg aggcaaaagc agatacacac agcccaattg tctatccgtt 3291541 aggaatcgta aaagatacaa aacaccgtaa ggaagcgaag gaattttacg aatacctgca 3291601 atctgatgaa gcaatgaaag tatttgagaa atatggcttt actgccgagt agcataagcg 3291661 cttcagaatt tttcacaccc gttgtgcttt cctttcaggt ggcggcagtt gccggaattg 3291721 ttgtcattat tctcggaaca cttgctggag catggatgtc acgggcatca tttttcggaa 3291781 aaacggcact cgaaacatgt tttatgcttc cgctcgttct tccgcctact gttgtcggtt 3291841 ttattctgat cgtcattttc ggaaagcaca gcttcatcgg acaagccatc gagtggattt 3291901 tccagcagcc tgtcattttc acctggtggg ccgctgtgat cgcctcggct gttgtagcct 3291961 ttccgcttat gtatcaatca gccaaaaccg gatttgctga cattgatccc gatatacaag 3292021 gtgcggcaat ggtagacggc gctagcagat ggaaagtgtt tatccatatc tccgtcccgc 3292081 ttgcctatcc ttcgttactg accggaagca tccttagcct tgcgcgggcg ctcggagaat 3292141 ttggcgcaac actcatgttt gcaggaaaca tccccggtgt tacgcaaaca ctgccgacgg 3292201 cgatatatgt cgcattggat tccggcaaca atacccttgc ttgggcgtgg gtcgtctgta 3292261 ttgttgtcat ttcctttttg atgctgtttt tcattcaaca gaaaaaaacg cactaaaaaa 3292321 actccccata acggggagtt ttttgattaa aacagaagct catcaggatt tggaccgaca 3292381 cgctcatctt tatttaatgc gtcaattttg tccatgtctt cttgagacaa ttcgaaatca 3292441 aaaatatcag cgttttcgat gatacggtgt tctttaatgg attttggaat ggttacaact 3292501 ccatgctgca gatcccagcg caaaatcact tgagccacag atttattgtg tttttcagca 3292561 atctgtgtca gtacttcgtt atccaaaagc tgtccctgca tgagcggaga ccacgcttcc 3292621 agctgaatgc cttgcccttt gcagtaatct cttaattctt tttgcgtcaa gcgagggtga 3292681 aattcaactt ggttcaccat cggtttgatt tcagcatctt tcaacagctc ttctaaatga 3292741 tgaacttgga aattgctgac gccgatcgcg cgaattttgc cgtctttgta cagcttttca 3292801 agcgcgcgcc atgtatcttt atatttatct ttgccaggcc aatggatcaa atataaatct 3292861 aagtaatcaa gctgcagtct ttctaggctt ttttcaaagg cagcaagcgt tgtttcatag 3292921 ccttgatctt cattccacac ttttgatgtg atgaagagct cttctcttgc cacaccggat 3292981 tctttaatcc cgatgccaac gccttcttca tttttgtaga tcgctgctgt atcaatactg 3293041 cgatagccat ttttaattgc cgctttcact gattcagtcg cttcattacc attttctact 3293101 ttaaaaacgc ccagaccgaa ccaaggcatt tcaactccgt tatgtaactt tacagtatct 3293161 tttaaacttg ttggcacttg aacctccacc ctttcactga aatgtaagcg tctatattat 3293221 ctcacattcc tctcagccga taccaataat acgcttaaga ccctcttttt gcttcttttt 3293281 tcacagcaca ggcaaatcca aacactattt ttttcctatt ttaacaatat tgagattaca 3293341 aatacattga gcagggtatg cgtgtagtgt aaccaaatga aaacaaagga ggaaacaact 3293401 tgaaacgtat tcgtatccca atgacacttg ctcttggtgc cgctttgaca attgcccctt 3293461 tgtcctttgc ttccgctgaa gaaaatcctg ctccgaagat gtcgcagaca actactgctg 3293521 gaacaactgc cgctgatgta ggtttaaacg tcaacctgga tgtacttgga attgccaacc 3293581 agatcgctga tgccatcaaa tccgcacaga atagggatgg ctttgtgaaa aacctcatgg 3293641 agtcttcctt ctacgcgtcc ggccaaaaat ataacgtcat ggtctttaat ttaagccagg 3293701 aatatgaaga tcatttgaac ggtgtgcaat tttacggctc agccgtttac gacggcatta 3293761 cgtatggcat ttgggtattt gaagatggaa cctttacaaa caaaggcgat ggcggctgga 3293821 tcaactgggc cttcagaggc tggttcgacc gggatggcag cactgtcgca tttcatcgcc 3293881 cttaatataa aaaaagctgg cgctctaacg ccagcttttt ttctgcattt attcgccgcc 3293941 ttcaagcatg gcggcttcga catcattaat gtattggcga agctcatggg agatgtcccg 3294001 ggaaatttcc ctctcttcga agagcgtttg aatttcattt ctgatcgcct gcacagcctt 3294061 cagcttcact tccagcttct gattttcaaa atgggcactt gattttaact catgatggct 3294121 gtgctccagc ctgaaaatta actgcttata gaatgtaatg acagataaaa acacttcttt 3294181 atgctcatcc gtcttatgtt tttccagata ttctatcgct gcttttgccg ttttcactct 3294241 tgttgcccgt atcaatcccg cttcatttaa aatcgacatc tccggctttt tatgttcacc 3294301 gaagaaaatc caatacatca gcctcttgag ccttgttttt gataacccga ctttaaacgg 3294361 gttggcatac aaaatttcca actcgttaaa tcgttcttgc agcacatttg ctgtttcttc 3294421 cgggatgtct ccccgctcca gcattttcat cagcgcctct tgctcagcct taaccccctg 3294481 cgcacggact tttcgctcgt gcttcttaat gcgattagat gatgtatact gctgaaaacg 3294541 aagatttttc attttctcat tgtattcagc tatcaccgca agagaggccg ttttgtttgt 3294601 ctcattcatg tcctctttaa tcgtttgaag ggctgttttg atcaacttgc gtctcgccgt 3294661 cagcagcttc ttatttcgtt cctcgtcctc ttcttctttt tcagtcagaa ttggcagcac 3294721 aacggtggca atgacaagcg tgcataaaat gacgccggct gctaaaaaga gaatcagatt 3294781 tctttccgga aacggcgtac cgtcctccag gaaatacgga atggaaaaag aacctgcaag 3294841 cgttactgct ccacgcacac cggaaatcga aattaacagc gtcgaacgaa gacccggttt 3294901 atagatgttc tgatctttat taaagaacca tttgccgttc cagaagaaca gcacccacag 3294961 gaatctaagg agcattaatg taaatgtgat gactaggata tagccgatca ccttcatgtt 3295021 gctgatggca gtgtcgttaa agataacaga aataacatca gggatttgcg tgccgagaat 3295081 aacgaagacc aggccgttca aaataaataa aataatgttc cacgtacttg aggagacgat 3295141 ttgcagcttg atcatcgttg attccagacg atcctgttca accgcatggg taataccgcc 3295201 agctacaaca gctaaaatgc ccgaaacgcc gatttcttca gctgccaaat aaatcacaaa 3295261 cggcgtcaga atttgaatca gcatatgcat cgtgacatcc tgcatgccaa ggcggcgcag 3295321 aaataggcga aaacgaataa tcaaaaatga aatgacaacc ccgcacagca agcctccgag 3295381 agaaataaag acaaagctga cagccgcttg tgctaatgaa aatgcaccag tcactgccgc 3295441 tgcaatcgca aacttaaagg ccaccagacc tgatgcatca ttcatcagcc cctcaccttc 3295501 cagcaggcga agaatccctt ttggcatttt cactcttcct gataatgcgc tgacagcgac 3295561 gacatcagtc ggtgaaagaa tggccgcaag tccaaaggcc gctgccagcg gaatagcagg 3295621 aatcatccag tgaatcgtgt agccgcctac aatcacagtc gcaaatacaa ggccgagtgc 3295681 aagcaataaa atcggagccc ttaaattcca aagctctgcc cgcggtgtcc tctttccatc 3295741 attaaatagc agaggcgcga taaaaagaac aaaaaacaat tcggtgttta attcaaaatg 3295801 aagtccctgt ggaaatgagg cggcaagaat cccaagagcc acttgaatca gcggcaccgg 3295861 aataaacgga ataaaccggt tcacgatatt agaaatcgca ataatcgtta ataatacgag 3295921 cacaactaaa aatatgtcca aatgcatgac ctccttcgtc tgttgtgtgt cggcatgatg 3295981 agccaaaaaa tctgtttgtc taaaagccct tgagctaggg tggccttgca tccgctatgt 3296041 ggtttcgcag gagttctctc cacacttgtc ttcttttata gtaccctttt tagggtattt 3296101 tttctcatga tatgctcaca gtgaactttt ttgcagaaga gcaaattata gaaaaaagag 3296161 acaggaagct actccctgtc tctcgtcttt ctttctcaat catgaaaatt cgtaccgtca 3296221 gttgttgctt taataatgcc cgcgcgaatg acaaagtcac cgaaatgctc gccttcctcg 3296281 cgttctttcg catagcggga aagaaggatg cgcagctcgc ttaaaatgtc tgcttcaccg 3296341 atgttttcac ggtacatttt gcttaaacgg cttccgtcaa acgcagcgcc aagatacata 3296401 ttatatttgc ccggcgcctt tccgataaat ccgatctcac cgagtgcatg acgtgcacag 3296461 ccgttcgggc atcctgtcat gcgaatggtg atttcctgat cacgaaggcc gttttcgtca 3296521 ataatctctt caatcttatc taacagggtc ggcaaataac gttctgcttc agccattgcc 3296581 aatccgcagg tcggaagagc gacgcacgcc atcgagctgc ggcgaagcgc tgaatagtgc 3296641 ttgccgtcag ttagtccgta ctgttcaatt aaagcactga tttcttcttt tttatcgctt 3296701 gaaacgttcg caatcattaa gttctgattg gctgtcagcc ggaactcacc tgtatgaact 3296761 ttggcgattt cccgcaagcc agtcatcagc ttataatcat cgtaatccgt tatacggccg 3296821 ccttcgacaa acagcgtgaa atgccattta tcctcgatgc cttccaccca gccatagcgg 3296881 tcgccgttat gatcgaaatg atacggcttc gcttcttcca ggctccagcc gagacggttt 3296941 tccaattctt cttttacgtt ttctaaaccg aggcggtcaa ctgtgtattt gaaccgcgca 3297001 tttttacgga cagaacggtt gccgtaatca cgctgaatcg taatcgtttt ttcagcaacg 3297061 tcatacattt gctcaggccg gcagaaaccg atcaccttgg ctaattgcgg atatgtcgca 3297121 gtatcgccat gcgtcattcc cataccgccg ccgattgcca cgttaaaacc gatcagcttg 3297181 ccatcctcga caatcgcaat gaatccgaga tcttgtgaaa agacgtcaat atcattagac 3297241 ggcggaacgg caataccgat tttaaacttc cgcggcagat agagcggtcc gtacattggc 3297301 tcgacttctt cctccggcgt gccggcaact ctttcctcat caagccaaat ttcatgatat 3297361 gctctcgtcc gcggcagcag atcatcactt aattttttag accactcgta tacctctgag 3297421 tggatttcag attgataagg gtttgatgca cacatgacgt tacggtttac gtctccgcag 3297481 gctgcgatcg tatccaaaag tgctgagtgg atcgtctgaa tggttttctt catgttccat 3297541 ttcagaattc cgtgcatttg gaatgtttca cgtgtcgtca attttaatgt gccgttcccg 3297601 tatttctggg acaggtcatc catgacaagc cattgttcag gcgtcgagac gccccctggc 3297661 atacgcacgc gcagcatgaa ctgatatgcg ggctcaagct tctgcttttg gcgttcattt 3297721 cggaggtcgc ggtcatcctg caaataactg ccgtggtgtt tcatcaggcg gttatcatca 3297781 tccggaattc ccgcactgat tcgatcgagc atcacttctt tcagcgtgcc gcgcaaataa 3297841 tcactttctt ttttaatgcg ttcaacatca cttggagagc cgtccggtgc ttttagaatt 3297901 ttggtcacca tgttgaaaaa ctcctttcaa gtcaaatcaa tatacatcac gctgatagcg 3297961 tttttgctgc tgcatatcgg caagataagc ctccgcctct tcgcggctca tattgccttc 3298021 tttttcgata atttcaagca atgtgttatg gacgtcatgc gccatgtgct tttcatctcc 3298081 gcaaatgtaa acagccgctc cttcttgaag ccattcaaac aattctgcgc tatgttcaag 3298141 catgcggtgc tgcacatata ctttttcttc cgtatcacgt gagaacgcca catccatttt 3298201 tgtcagcaca ccgtctttga gccaattctg ccactctgtc tggtaaagga aatccgtgac 3298261 aaagtgctga tcgccaaaga acatccatgc ctttccttcc gctcccgtct cctcacgctc 3298321 ctgcataaac gaacggaaag gtgcgacgcc tgtcccaggg cccaccatga taatcggtgt 3298381 ttcagggtct ttcggaagct taaagttttg attgtgctgt acataaaccg gcagtgtgtc 3298441 tcccggctgc agtcgttccg cgcacaaaat cgagcagacg ccttttcgtt cacggccgtg 3298501 cgcatcgtag cggactgcgc cgattgttaa gtgcacttca tccggatttg cggataaact 3298561 gcttgcaatc gaataaaggc gggcaggcat ttttcgcaaa atcgagacaa actcctgcgc 3298621 agatacacta aatgggccat agtcacggac gagatcaagc aaatcgcgcc cttcaatata 3298681 ggcttttaca ttctcctcat ttcccggggc taaaagctct ctaagctcat cgttccctgt 3298741 cagctgggct gcctgttcaa gaagcggttt tgtgagaacg gtaatctcat agtgagaaat 3298801 cagcgcttct ttcagcggtc ggacatcacc ttgcttatta agcgtcacaa tttcttccgg 3298861 gtcccaattc atttccttaa ggagcagctc gacaagttcc ggatcgtttt ccggatagac 3298921 gccgaggctg tcaccaggct cgtaagtcag gccagatcct tcaagagaca gctccacatg 3298981 gcgtgtttct ttatttgatc ctctgccgtt taaatttaaa ttttctaaca cttcagcccg 3299041 aaacgggttt gttctggaat acgaagactc accggtttgt gacgcagccg ccggcgcagg 3299101 cgcggcgctt ccgcccccag cttcatttaa tcctttcaat acaccctcaa gccattcggc 3299161 tgccggttca tcatagtcaa gatcgcaatc aacgcgcgga gaaatccgtt ttccgccgag 3299221 ttcttctaag cgttgatcaa attctttccc tgtctggcag aaaaattcgt acgaactgtc 3299281 accaagcgcc aaaacggaaa agcgcaggtc ttcaagctta ggcgcccgtc ttccgtgcag 3299341 aaattcatga aacgacagcg cgttatcagg cggctcgcct tctccatgcg tactgacgac 3299401 gattaaaaga ttggttacct tcttcagctg attcggctta aaatcgctca tggatgagac 3299461 ggtcacttga aaaccgctct gttcaagctg cttgccggca ttttctgcaa gcccctgtgc 3299521 gtttcccgtc tgtgaaccat aaagaacggt cacttctttt gaaacggccg gtgccggtgc 3299581 ttccgctgac acagctgccg ccggcgtacc cgcagcttct tgggcggaaa cagattgagc 3299641 ggataaatat ccgctcagcc agattttctg ggattcggtc aaggtcggca gaaggcggtt 3299701 aaggagctct gcctgctcct gattaaacgg actgttcatt acctgaagtt gcaacgtatc 3299761 cacctcacaa agttataaac tgatcgaaaa ttgcatctaa ttgaacttta ccggaatact 3299821 aggcttaagt aaaatatatt tacatgatga taactattaa gaatcctaat gataaaacgg 3299881 ctatgcttca tgtaaataga aaaaagagaa ggactccctt ctcttcattc agcaatctga 3299941 tataagtgag gcggcacagc ggttacaaac ggactggctt cacctgtata aaataccgcc 3300001 agcatgtgca tcgcacgggt gcacgcagta tataaaagcc tgcggtcgtg ctctgtatga 3300061 tagtgttctt cagatgcatc atagacaagc actgcgtcaa attcaattcc cttcgctaaa 3300121 tacaccggaa tcacgcaaac acccttttga aatggttgat tttctttatg aatcaggcga 3300181 acatctgtat attcactcat gtgggcgtgc gcctgtatgc attgatgcgc agtcttgcag 3300241 atgacggcta ttgtttcgtg cccttttttc ttgagccggc caatttcttg cgcgagcttt 3300301 tggcaaaggc tctcatgtcc ttcagttttg acaacgagcg gcatttcccc gcttctatta 3300361 aacggctcaa tatccgctcc atcttgaagc atcgctttgg taaactcgac aatctgcctt 3300421 gttgatctgt atgttctctt taaacgaaca tactcagcag gctcatcctc aaagcacgca 3300481 tccatacgct gatccccgtt tatggtatgc gcgtagatgg actgattgat atcaccgagc 3300541 actgtcatgc tggcagccgg aaaaatgctt ctcatgtaag ccatctgaaa cggtgaatag 3300601 tcctgggctt cgtcaataaa tagatgtttg attttcgtat ttttctttct gccctcaatc 3300661 agatcctgca tataaagaaa cggtgccgcg tcctcataga gcaatttatt atccgtaaat 3300721 gccgaacggg tcagctcacc tatcgcatcc atcttctcat gttgaaattt tcctccccag 3300781 ccagaaaaca attgcaaata aagttgtgta acatcaagaa atgcaaggag cctgactgcc 3300841 tgtttgagcg gtttgaaagc ttttttcaca atgatggcgg caagcagctg ctgctctctt 3300901 tgataatcgt taaacgtact ctcgctgaac cgtttccttt cctgcagttt tttgtacacg 3300961 tccaagtagt cctctttgtc aagcagctca gcttcatgaa caacccaatc ctttcgccgt 3301021 tcctttttct caagcttgtt aagctcactc agcagccact tcgcggtttg ctccatccga 3301081 ttcggaatgg agtgattttg atccaatgag taaaaatagg attgaatttg ctcctttgtg 3301141 atcagctttt gtccgcggaa tataatattt ttaaaaatca tcccttcaga ggaaagccgt 3301201 gtgacgtatt cattaatgaa ttgctgaaag gataaacccg ccttccatgt gattcctgca 3301261 agccttgttg gaaaatcgcc tccctttgtt tcggtcaggc aatattcgag ctgatcaaag 3301321 gggctttcac atttgaactt gcggccaaga cgatgctcga tatattcctg aaacgtcgcc 3301381 tgctccatat tctcttctcc taactccggc aaaacagagg agacatagct gttaaataag 3301441 aagttgggtg aaaacaaaac gatttgtccg gcatcaatga caccgcggtg cctgtataac 3301501 aaataagcga cacgctgaag cgcagccgat gttttcccgc tgccagccgc tccctgcacg 3301561 atcaggatct tgcttttttc attacggata atctgatttt gttctttctg aatcgtagac 3301621 acgatgtttt tcatttgggt atcagagtga tggcttaata cctcttgcag catttcatcg 3301681 ccaatcgtca tatcggtatt aaacatcgcc ttgagagtgc cgtttttgat cataaactgg 3301741 cgtttcagca ccatttcccc ttctatcgtt tcaccgggca cctcgtactc cgcttttcct 3301801 ggggaataat tgtagtacaa acttgatatc ggcgccctcc agtcatagat cagaaagtgt 3301861 tcctccttct catccaaaca ggaagctaaa ccgatataaa ttcgctctgc ctgctcctcg 3301921 ccgttttcaa taaaatcaat ccggccgaaa taaggcgatt ttttcaattg atgaattcgt 3301981 ttgagctgct gatccatgcg ccgatgattg tgttcccgat cagacagcag ctctgcctgc 3302041 tgcttaatgc tagccatcgt ttcaatcgct tcatgggcat catcaaaatt aaccttaaca 3302101 tcctcccaaa agctttttct taatccgatg atatcatgct tcaacccgcc cgcagacgtt 3302161 tccagaaacc gctctttttt ttcgagctcc ttcagcacct catctattct cgactgctct 3302221 tccttccatt ccttatcctg ctgattcatg aacggcacct ccagaaaata gttgacaaac 3302281 atagatgaaa tactgtaaaa tataattgga tacatatatt aaatatatga tgcaaactgg 3302341 caaatacaat ttataatagc acattcaccc aataccaatc aaggtttggg ttatttatat 3302401 tatgcagaaa aaaaccgatt tcacttcgaa atcggttttt ttgctattaa ttatctaagc 3302461 gaaaagaacg gtttggcagc ttccaattaa acatatagga acaaacccgg caaacaacga 3302521 gcacgaaaaa cagaacgtat aagccgaacg agttccccag ccagcccaag ccgacgatta 3302581 aaccgccgag cgccgcccat accgcataga tttccgcttt cagcacaagc ggtttgcgcc 3302641 cggcaagaag gtcgcggatg atcccgcccc cgcttcccgt cagcaccgca gccacgatca 3302701 cggcactaag cggatggccc attttgacgg catacagtgc gccttggata gcaaaggcag 3302761 cgaggccgat cgcatctgat aaattgcccc acttattcca atgcttcagc agcagcttcg 3302821 gaaacagaaa cacaattgta atagataaaa gcgcgatttg aaagtacgct ccctgctccc 3302881 atagcgctga caccggaaca ccgatcagca aattgcggat cgctcctcct ccaaaagctg 3302941 tgacaatccc taatatataa actcctaaaa tatcatattc ctcttccatc gcaacaattg 3303001 cgccgctgac tgcaaacgca atgatgccaa tcacactaag cagctcccaa gccattctga 3303061 tgactccctt ttatgtttgt taaattttct gacgacctct agattttata atcgctccag 3303121 cgtaaaatca ataacatttt catgagaaaa aaagataaat ttagagggaa tacggctatt 3303181 gctgatggac atgagtttgc gaaattaaaa aagcgcccgg catacgcggg cgcttttttt 3303241 gttattcaga tttttcgcct ttcagcaggc acataaaaat gataatcagg ataaaagcaa 3303301 tcagggccag gaatggaatc gtaataaaac caaaccagtt aatatattgg cccgagcacg 3303361 gcacgccgct gacacatggc ttaatgccgc taaagccggg cactttttgc tctaagtaat 3303421 gcatgatcga aatgaatgcc ccaataatcg ccatcgggag cacatatttt ttcactcgtg 3303481 tgtccccttg aaaggtggcg atgcctaaaa tcaggacgag cggatacatg aggatacgct 3303541 ggtaccagca cagttcacat ggaataaact ttctgatttc actgaaatac aggctgccca 3303601 gcatagcgat aagagccaca acccaggaag catataaaaa tacgattcta tttttcatat 3303661 tgttacttcc ctttcagctc tttttctatt gtctctttga tttcatcata atccgcaaaa 3303721 tttttgatca ctttatcatt gacgtaaatc gtcggtgttg cctgtatgtt cattttttga 3303781 ttaaggtcag aatccttttc cacttgagaa gcgaatgttt ccttatcaag attttccttg 3303841 agcgtctcag gttttatctt tgtggtgctt tttgcaagat caccaaggag gcctggggtt 3303901 acccattcct gttccgtatc cggctgtttt tcgaacagct tttcatggaa atcccagaaa 3303961 gagtcagggt cttccttcca tacttcttca gatgcaagag ccgctaacct tgaacctttt 3304021 ccatggaaca tgacgttcac gaaagaaaat ttcacatcgc ccttatcaat aaagtctttt 3304081 tgtatttttg gaaagatgtc actgttaaac accttgcaag acggacattt gtaatctccg 3304141 aattctacta cagttaccgg tgcatcgtcc ttgccaagca caggctgccc tttgatagac 3304201 ggctgtccgg acaccgcatc attgccttgt tccgttttgt tattaatgat gacaatggct 3304261 gctagcaata caacaaccac aaccgtaagg atgaccgcga atttcgcaga agactgctgt 3304321 ttctttttca ctccgacacc tcatcgtttt aaaattaaaa aagaagcgga tcgcaattga 3304381 cccacttctt tattttaaca agacaagcgc tgataagaaa accccgaaaa aatgaattct 3304441 ctccgacaat ttatttgttt ttgagacgca tgacgcgcat ggcgttcgcc acagcaagca 3304501 gtgtaacgcc gacatctgag aaaaccgctt cccacatggt cgcaattcca aatgcaccaa 3304561 gaatgagaaa gatcgctttc acacctaaag caaagccgat gttttgccac acgattcgcc 3304621 gtgtccgttt cgcaatccga atcgcttctg ctatttttga cggctgatct gtcatcagca 3304681 cgatgtctgc ggcttctacc gcggcgtctg agccaaggcc tcccatcgca acccctatat 3304741 ctgcgcgtgc aagcaccggc gtatcattga tgccgtcacc gacaaaaatg agtttttcac 3304801 taggcaaaag cttagcttct aatgcttcga cctgcgcgac tttatcttgc ggcagcagct 3304861 ctgcatatac ctcaccaatc ccaagctgtt ttccgacggc ttctcccgtt tgtttcgaat 3304921 cacccgtcag catagctgtc tgtttgatcc caagcgactt cagatcagca accgcctgtg 3304981 ctgcgtcttc ctttatctca tccgctatga tgattgctcc ggcatagcgt tgatctacag 3305041 caacgtgtac gattgttcca gcattttcat ccgggacatc ctcaatttgt tctctttcca 3305101 tgagcttttt attcccagca aggatctcag ttccatttac ctttgcaaaa atgccgtgac 3305161 cggagatttc ttcgtatgac tcaatctcat cggaggaaag cattttcccg taagctttac 3305221 gcacagattc agcaatcgga tgctgtgaat gaagctcagc gtatgccgcc gcttcaagta 3305281 atctatcctt tgtaaaacct tccgcgggtt tgatttctgt cacttcaaag ctgccttttg 3305341 ttagtgttcc cgttttatca aacaccgcgt atttgacttg attcaaagct tctaaataat 3305401 tgcttccctt tacaagcact ccggcctttg aggccgctcc gattccaccg aagaaaccga 3305461 gcggaataga gacaacaagc gcacaaggac aagaaatcac taaaaagata agcgcgcggt 3305521 acacccaatc ggaaagcgcg gcgccagaaa gaacaagcgg cggaacaaag gccagcaata 3305581 ccgcaatgat caccacagca ggtgtataat acttggcaaa cttcgtgata aagttttctg 3305641 tccgggcttt acggctgctc gcattctgaa ccaagtctaa tatttttgat actgctgatt 3305701 cctgatagcc ctttgtgact tcaatatgca gaacgccgtt ttgattgata aagcctgaca 3305761 ttacatcttg tccttccgca gcttttctcg gaacggactc acctgttaaa gcagatgtat 3305821 caaccatcgc tgacccttgc acgaccttac cgtccagggg tatgctttct cccggattaa 3305881 ccacaatgat gtctcctgtc tgaacgtcct ccgacgaaac ctgttcgatg ccgttctttg 3305941 ttttgagatt ggcgtaatca ggccgtatgt ccattaacgc actaattgat tttctggaac 3306001 ggctgaccgc ggctccttga aaaagctcac cgatttgata aaacagcata acggcgaccc 3306061 cctcagggta ttgctgaatc agaaaagcgc cgattgtggc aagagccatt aagaaatgct 3306121 catcaaacac ctgaccgcgg atgatgtttt tgactgcgcg gattataatg tcaccgccga 3306181 taatcaaata agcaccgagg aaaaggaaaa attcaatggt tcccgactga accaaatatg 3306241 ccgctgcgcc gagaatgaca gccgccgcca ttctgatcag catattgacc attcgattac 3306301 gatagccatc atcagctgat ttctttatat gcttttggcg aaccgttaca tgcggatcaa 3306361 ttgatttcac ttttttctct actttattcg tgacccattg ctcttctttc ccatcggctg 3306421 agacagttaa ggtgcttgcc gcaaaattta ccgcgcatcc gttaatgcct tttatgcctt 3306481 tgactccatt ttcgattttt cgggcacaat tgctgcaatc caaaccgtcc agaacatatt 3306541 cctgtttcac tagtctcacc ttaccttccg atttagggtt ccctcttcaa agcgtatcaa 3306601 tgagtattgt atttatttta tatatatgag catatactca tatataagtt acacctatta 3306661 tatgttgttt tccaagaaag tgtcaatgaa aaacaaaaac cggcatatag ccggtttttc 3306721 attttacttt ttgcagacga agagcattca gaacaacgga aacggagctg aatgccattg 3306781 ctgctcctgc tatccacggt gctaaaaatc caagtgctgc gattgggatg ccgaggctgt 3306841 tatagccaag cgcccagaat aagttttgtt taatgttttt cattgtcaat ctgctcatgc 3306901 ggattgcgtc ggcaatgctg ttcagatcgc cgcgaataag tgtaatgtct gctgtttcca 3306961 tggcaatgtc cgtgccagtt ccaatcgcca tgccgatgtc agctgtggca agcgccggcg 3307021 catcgttaat tccgtcgcct accattgctg tctggcggcc ttctttttgc aagcgggcga 3307081 tttccgccgc cttttgttca ggaagaactt ccgcaatgat attcgcaatt cccgcttcct 3307141 tcgcgatggc ttctgcggtt ctgcgattgt ctcctgtcat catgatgaca tcaagaccca 3307201 actctttcag acgggcaaca gccttccgcg acgtatcctt aatcgtatct gcaactgcta 3307261 ctagccccgc tgcttctcca tcaatggata caagcataac tgttttccct tcggcctcta 3307321 gctcttccat ttgggcgaga agagccccat gctcaacctg ttcgctctcc attaattttc 3307381 ttgtgccgac gagaatgctt tttcctccgg cttcagccaa aatgcctgcg ccgacttttg 3307441 cttcaaagcg ggtaagtttc ggtatctcaa gccctttatc tttcacgcca gcaataatcg 3307501 cttcgccaag cggatgctct gatcccgttt ccgctgccgc tgcaaattga agcaaatctt 3307561 tttcttcaaa acggccgaat ggaatggcat ccgtcagacg cggcttcccg tttgtcacgg 3307621 ttccggtttt atcaagaaca attgtatcga gacgatgtgt tttttctaaa tgctcgccgc 3307681 ctttaaataa aatcccgaat tcagcagcgc gtccagatcc agccattatg ctcgtcggag 3307741 tggcaagacc gagggcgcaa ggacaggcaa tgacaagaac cgcaatgaac ttgctgatcg 3307801 cttcggcaaa atcgccagga gccgcccaaa gataccaaat gagaaaagtg agaaccgcaa 3307861 tccccaatac aatgggtaca aaaatgcctg aaatctggtc agcgagacgc tggatcggcg 3307921 cttttgaccc ttgtgcttcc tcaacaattt tgatgatatg agaaagcgca gtatcctttc 3307981 cgacgttgac agctttaatt ttcagaaagc cgtttgcgtt aacggttgaa cctgtcacgc 3308041 tgtcaccagg atttttgtca acaggaagac tttctcctgt aatcatcgat tcgtcaaccg 3308101 ctgaacggcc ttcaaccact tctccgtcga caggaattcg ttcgccaggt ttgacgtaaa 3308161 caatgtcatt aacaagcact tcgtcgatcg ggatgatttg ctcctgtccg tctcttacaa 3308221 cagtagctgt tttcgcttga agcttcatca gctttttaat cgcatccgag gaacggcctt 3308281 ttgcttttgt ttcaaacaac ttgcctaata aaatcagcgt cagcaaaatc gcgcttgttt 3308341 cataataaag gccgtctgta tgcccgtgag agccaatgct ttgaaaagtt agataaagac 3308401 tataagcgta agcagccgtc gtaccgaggg cgaccaatac atccatattg gcgcttttat 3308461 ttctaagcgc cttatacgca cccacataaa acggccagcc gatcagaaac tggactggtg 3308521 tcgccagcgc aaactgcatc cacggattga gaaatatatc cggtacccaa atgaatgatg 3308581 taaatgtaaa atggctcacc atcgcccaaa gcaatggaaa tgacaggaca gctgaaaaaa 3308641 tcagtctcgc cgtttgcttc cgttcttctt tctttttagc agcagcctca ctgtcctgtt 3308701 cacccttcaa ctttagctta tatccaagct tatctaccgc ttctttcaaa tcgctgacag 3308761 acgcttcttt tggattgtat tcgaccgtaa ctgtttctaa agcgaagttt actggtgcat 3308821 ttgcgacgcc ttctattttg ttaagccgtt tttcaatccg attggcgcaa gccgcacagg 3308881 tcatgccctc aatatcgaat tcagcttttt ctgtaacgac gtgatagccc agcttctcta 3308941 ttttttcctg aatcgctgca gtccctgttt cagcaggatc gtagattaca tttgatgttt 3309001 ccgttgccag attaacattt gcatccgtga caccgggcat ccgcttcagg cctttttcaa 3309061 ttctggcagc acatgccgca caggtcatac cagagacctg catcgcgatt tccttttgtt 3309121 cactcaacat actcactcct ttatatacac ctggggggta tataaaaatg aaagaaatat 3309181 cgcgcctccc taaaggcgcg ataccttgaa tcacttggct acgtcatagc cctgatcttc 3309241 tatcgcatcc gcaatatctt tgactgatac tttgtcagca tcaaacgaaa catcgacttt 3309301 acccgcttcc agattgacat gaacggcact gacgccgtcc agttctccta cgcttgtttc 3309361 tactgctttg acgcagtgct gacaagacat tccttcaact tgcaatgttt tttgttccat 3309421 atcaattcct cctgtttatt ctttctattt tcatcctacc atacccccgt agggtattac 3309481 aataaaaaac gctttatgat tttgtgaact ttttaaatac gtccaaaagc tcagaaatgg 3309541 cctgttcccc gtctccgctt ttgatggcat ctgctacaca atgatgggca tgatcctcaa 3309601 gcaaatgaag cgccacattt ttcattgccg cctgaacagc tgaaatttgc acaagaatat 3309661 ctacacaata tctgtcgttt tccaccatgt tttgaatgcc tctgacctgg ccctcaatcc 3309721 gcttaagccg gtttgtaatc tgatcctttt ctttcgagct tttatggttt aatgttttat 3309781 gttcgttatg cttttccatg cgtacacctc tgtttaatga tattaattcc cattatactg 3309841 attgtccaaa cggttgtcta agcatgccga cgcaaaaaat gaatcagtta ggttttacca 3309901 tttgatcagg agggtatata cttctgttga taacgctttt aaaggggaga agaaaagtgg 3309961 atacgatcaa ggttggaata ttaggatacg gattgtccgg ttctgttttt cacgggccgc 3310021 tgctggatgt tctggatgaa tatcaaatca gcaaaatcat gacatcacgg acagaagaag 3310081 tgaaacggga ttttccagat gctgaggttg tacatgagct tgaagaaatc acaaatgacc 3310141 ctgccattga gcttgtcatt gtcaccaccc cgagcggcct tcattacgag catactatgg 3310201 catgcataca ggccggaaaa catgttgtga tggaaaaacc aatgacagca acggccgaag 3310261 agggggaaac attaaaaagg gctgccgatg aaaaaggcgt attattaagc gtatatcata 3310321 accgacgctg ggataacgat tttttaacga ttaaaaagct gatctctgag ggatcccttg 3310381 aagatatcaa tacatatcaa gtttcctata accgctacag acctgaagtt caagcgcggt 3310441 ggcgggaaaa agaaggcact gccactggta cgctgtatga tctcggctcc cacatcatag 3310501 accaaaccct gcatttgttt gggatgccta aagccgtgac tgcaaacgtg atggcccagc 3310561 gggaaaatgc cgaaacggtt gactattttc atttaaccct ggattatggc aagcttcaag 3310621 ccattctata cggaggatca atcgttccgg caaacggacc tcgttatcaa atccatggaa 3310681 aagattctag ctttatcaaa tatggaattg acggacagga agacgcactc agagcgggaa 3310741 gaaaaccaga ggatgacagc tggggtgcgg atgttccgga gttttacgga aagcttacaa 3310801 ccattcgtgg ctccgacaaa aaaacagaaa cgattccatc agtaaatggc tcctacctta 3310861 cttattaccg taaaatagcg gaaagcatac gagaaggtgc tgcgctgcca gtcactgctg 3310921 aggaaggtat taatgtcatc cgcatcattg aagccgcgat ggaaagcagt aaagagaaac 3310981 gaaccattat gctggagcac taaaacaaaa gcctccccaa ataaggggag gctttttcat 3311041 tagaatgttt ttcctgcttc tttcgcacgc gcaatcgcgt cttctttgat ttgctgtgct 3311101 ttatcaggct ccgcattatg tccctctacg aaaatgccat cgaatgatgg tacgccgaag 3311161 aagttcatca tgatgccgat gtagcggtgc cccatttcca tctcagccgc agggccttct 3311221 gaatagtagc cgccgcgcgc ttggatatga attgcttttt tatcagttaa caagccgaca 3311281 ggaccttgtt ctgtgtattt gaatgatttt cctgcaacag caacagaatc gagatacgct 3311341 ttcatcactg gcgggaatga gaagttccat aaaggagtaa caaatacgta cttatcagct 3311401 gatgcaaatt gatcgctaag ctctcccaaa cggcctactt tcgctttttc gctttcagaa 3311461 agctcttcaa agcctgtacc tgactgaagc tttccccatc cgctaaatac atctgcgtca 3311521 atgtgcggaa tgttttcttt gtacaaatcg atatgtacaa cttcatcatt tggattcgct 3311581 tctttgtaag attcgataaa tgctttacct gttgccatac tgtacgaagt tgcttcgtca 3311641 tgtggatgag cagtgatata taatactttt gccattttta ccagcccttt cgtttttaaa 3311701 aatcacacat caattattat catacagatg cataatgatt attctgtctc tcttagactt 3311761 tattatagag acaaagaaat ttactttcaa gtaaaacatc tcgaattaaa gattatttaa 3311821 ctttcccaaa cagcttactt ttcaaaagct gttctcaagc cggaatacag cgcggacaat 3311881 tctttactga tccgaggata atgagggaca tgcggcactt gaatatccgc aggcatcctt 3311941 ttcatgataa aggattgctc agcctgttca aaaaacgccc gcagctggtt gatctcttca 3312001 tcagaaaacg gagcagacgg acggcggtga gcttgcgccg agagcaaata gtaccctaag 3312061 tgctgagcac cggaaatggc aggccagagc gcatccgcat tcgcgtgagg aaactcgcca 3312121 agcgccttgt catacgcatc ccgaagcctg acaagactca cccttaactt gtgttcgtcg 3312181 gcaatttgcc cggttaacag tttctccata aactgccctt ccagccggat gacattccgc 3312241 acaagttctg gcagccgctt ggttgaaaac cgccgccaca aaagcattgt tcccaacagc 3312301 ccgatcacgc tgccgacagc tacatcagtc agcctcgcta tcataaaata accggcgccc 3312361 gccccgccat gcatactttc tgtgataaca agcgcatttg cggttaaaaa gggaacagcc 3312421 agcgcataat tgcggacgat cagcatctca agaagacatt gcagcgctgc aatacaaaac 3312481 gcaatataaa caccgcccgg cttaaaaaac aggattgcgc ctgccagtat aacaccgatc 3312541 accgttccgg ccgaacgctg aatagccctg tgaagcgtaa aaacaacagt agtgccaagc 3312601 atgaccgctg ctgccgaaag cggaatccaa taggagcgtg caaagccgaa tgcgagggca 3312661 aacatatcgg cggcaaacag aacaattccg tactttaacg ctctaatcaa aactggagac 3312721 ttccagtcaa aggcatttct caaaaagtaa aaagaggatg gcaggcggct tggttccccg 3312781 tcaagctgct tatcaaaacg tcctgaagcg atatacaaaa cctcattgat ttcttcaaac 3312841 agcttccgcc taggctcaga ttcattttca ttaatctgaa acgtattgaa aacccgtgca 3312901 ttcgcaagca tatctccggt ttggcgaagt gccttttcaa tctgcgcggt ctctctgtcc 3312961 ggcgtttcag ctgaaaaatg aataatggca ataaatatgt cgtcagcttt ctcaaggagg 3313021 cgaaaaaatc gttcatcatg ccgcgatttt ttccgtctgt tccctttccc aagaaccgtt 3313081 tggcgggctg ttctaagcat gagcaccgtc tgatgctgtg cgttatgaaa acctggcgtt 3313141 ccgacggctg aaagacatgc agccagctga tgatatgttt tttgcagcac cgctccctcc 3313201 ggtccatgtt tgttccataa ccagccgatt aaagcgatac ccatggcgaa aatgccgccg 3313261 agaaacgtca gtcccgctct gaacagcgct tgtgaaggat cggccggcag cccggaactg 3313321 actaaaaagg caaggacaaa aaacatcggc gcagggcctt gaatgccgag cgcgctaaaa 3313381 ataaacatcg ccgctgcacc gatcagcccc aaaacagccg ccatcatcca aagcatcccg 3313441 gacaaaagcg tccctaaacc aaatgagagg gcgatcccaa tagaaaccaa gagcagcttc 3313501 aaggcgcgct ttttgtacga ttcaccgccc gcatataaat aaacaaagcc tccgatactt 3313561 gcaattaatc cgtaatccgt gtgacctgcc aatgcaccga ccagcacagg aaaccctgaa 3313621 gcgaaacctg atccgatagc ctttttccaa ggaaatggat ttgcatgaat gcgaaaggca 3313681 tccttcacga taggcatgat tctttgattg ttcgcagcag ttttgttcat ttgacaaaat 3313741 ccttttcaat gaatgtgtag aacttttcca gtttcttcgc tttagtatgc ccaaaaacgc 3313801 ggttagcttc tcaattggtg cgcacgataa aaaaacagag acttataccg tctctgcttc 3313861 attacatcag tttattataa aagcggcacc tgtcaggact gttttgtcct tctgccttcc 3313921 ttcaagagca ggtgaataaa aaataaagga taaatcaata gatacccatt aaacagccac 3313981 cacacaagat caaagtcact gctgaatgtc cagaatgata gcgcctgcag acctgaacaa 3314041 caggtcagca caagagaaat cagcgccatc agcttccagt cagcacgatt cacccgctgt 3314101 aggtacaagc tgtacaaccc tgtgacagaa atcaggatat ccagcggaaa aaaagaccag 3314161 ttccaagcga tcataaacgg atggtcatga tgtttaaaag cccagctttc cggtatgagc 3314221 gaaaatccgg ctgacagcca gtacaagata aaaccgatat cagtcacgag aaaaaacagc 3314281 ttcatatatc tcatttgtac tgcccgcttt tatgtaccgg ctcagacacc gcaacatgct 3314341 cgatcaggtt taaagacaca acaccggcaa taatcaatcc aattgaaatg actttcatga 3314401 cactcacatg ttcttgaaaa aacaaaaaac caacgactgt aatcaagaca attcccatcc 3314461 ctgaccatac agcataagca actgatacat caatggattt aagcgtaagc gtcagaaaga 3314521 aaagactccc tccataaaag aaaatcaaca gcaaactggg aataagcttt gtaaaaccag 3314581 acgatagctt catgctgaca gttcccgcaa cctcaaacaa aatcgccaag catagaaaca 3314641 cccaattcat gtggcatcag cctcctcatc agctgttata ccgttaaaca aaacatctac 3314701 aattgattca agtacctctc ctgtcgtgaa ctgatgtttc agcggatatt cagggtcata 3314761 cacttgattg atgctcccta tatacatgtg aacaaacagg tccggattga tgtttctgat 3314821 tctcttttgc tgtttgcact catttaataa tgctaggaca atcgcccatt cttccttaat 3314881 aaacgcgtct aatgtaagcc acgcatcgta atggtatttc tttagttcat ttaataatcc 3314941 catgttcagc agttccatcc cctgcggaag gctgatcagc atttgtttca ccttttcgag 3315001 cacatttaaa ctttcatttt catagatgtc tctttctatt tgcttcattt cagctataaa 3315061 ttgttcgaca accgcctcaa caagctgatc tttagatgaa taatatgcat agagcgtccg 3315121 cttgctcgtt cccagcgctg ccgccaaatc attcatcgta aatgaaaatc ctttctgctt 3315181 gatcagccgg aaggtttccg ccagaattct tttatccata ttaatccccc gctttcggta 3315241 ccaagaaaac tatttcggta ccaatattat acggcagaaa tttatggaaa tcaacaatat 3315301 ataaaaaaac ctctcctatt gggagaggtt taaaagacac tgcggaccaa accgccgtcc 3315361 gcccgaagtg ccgcgccatt gatcgcagag gaaagcggac tgcttaaaaa tgtaacgaag 3315421 tgggcgattt cttccggacg gatcagtctt tgaataatag atgtcggccg gttttctttc 3315481 ataaaacgtg cctcagcttc ttgaacagtc aggttttcac caggatacag cgagttcagc 3315541 atggtttcca caccctctgt taaggtagag cccggcatga cggtgttgac tgtgacattc 3315601 gtgccggttg ccagctccgc caaactgcgg gaaatggaca gctgcatcgt ttttgtcgca 3315661 ctgtaatggg ccatttcctg tgacggcata atcgccgctt cactggcaat gaaaatcaca 3315721 cgcccttctt ttttctctat catgttatgc aaatacctgc gtgtcagcct tacaccgctc 3315781 ataatattca cttcaaaaaa acgaaaccat tcatcgtcgg gaatatcaaa gtactccgcc 3315841 ggttcaaaaa tccctaaatt gttgaccaaa atatcaacct ctggatatgc ctgaaacagc 3315901 tcattgcagc cttcttctgt tcccaaatca aatgcagccg gataaagaac cgcttcagca 3315961 tgttgtgttt tcagttcatc tatcgtttga ttcactttct cttcccggcg tccgttaatg 3316021 atcactgccg caccttcttc agctaacgaa gaggcaatag cttttccgat ccctgatgtc 3316081 gaaccggtca ccagtgcggt ttttccttgt aaattcagct tcattattca tccctccgtt 3316141 tttgattcct cttatttatt gacagaaatc tgattggtga aacatctgct ctgcaatcag 3316201 tatgaaacag ctgggattga aatggaagta cgcacttttt ggtgcctgtg gtttggagaa 3316261 aaaataaagc agaacctctt aagaggttct gctttattgt cagtatgtat ggagacggtg 3316321 ggagtcgaac ccacgtccag aaacatcgat tacttaagcg tctacgagcg tagcctgcat 3316381 atttatggtt tcactcatct tcttgcctgc gggcgggcct tccgagagct agtctgttca 3316441 tctcttctta cgttctcaga cgggaacgca agcgtagcct acttggatgt gctcttcaca 3316501 gacacatagg caatgtcagg aagagctcgc tgcgcttatt aggcagctaa tgctacgttt 3316561 tggttaaaac tgttagtttt gccagttata tttaagtgcg tgtttacgag atcgcctctc 3316621 ggctcgcagc tcaagctcga tccatccctg tcgaatccgt aacgtcccct tggtataagg 3316681 gaaatacggg agaaaatatc aagctctcac tcaaactggc tatagtctta ttataacatg 3316741 atcacggctc ttttcaattg tcaaatcctt caaatgaatg gcgtcgtgat ctgatcgtga 3316801 acacagtata gcacaggcct gattttcgaa tcaagcacta tgcctttaga agcctttttg 3316861 actgtctctg aacgctcttt cgatttcccg cttcgcgtcc ttgcgcttca gatcttcccg 3316921 tttgtcatag ttcttcttcc cttttccaag gccgagaagc actttggcaa agccgttttt 3316981 taaatacagc ttcagcggaa cgagagaata gcctttttcc tttgttaacc cgatcagctt 3317041 attaatctcc ttgcggtgca ttaacagctt tcttgtccgg agcggatcgt ggttatagcg 3317101 gtttccctgc tcatatgggc tgacgtgcat attgtggaga aacacttctc cccgttcgat 3317161 tttggcgaag gaatccttaa ggtttacgcg gccggcgcga atcgatttga tttcggttcc 3317221 ttgcagaacg atgcctgttt cataggtttc ttctataaaa taatcgtggt tggctttctt 3317281 attttgagat aatacttttc ctgacccttt tggcatgcca gaacctcctc tctctaagga 3317341 aaaactgtcc accttttgcg atacgctcta ttttaccaaa tgtcacgtac cgctacaatg 3317401 aaaagctgtt tccgaaagaa agcaaataga gcgctgcggc cctatttgct ggttgagctg 3317461 ctatttcttc tttttccgtt tctgtttcgg agcattctgg aagccgcgtt ttttcttttt 3317521 cttcttcggc ttagtgaacc actccccttt ttcctcagac ggagctggag aaacaggtgt 3317581 attggtgctt tgaacacgtt ttctggcagg ctttccgcgt tttctgctcc ggctgctgtc 3317641 caattctctc ggacgccgcg gagtgccttt catgccgaca atttcaaagt cgatattgcg 3317701 ctcatcttta ttgacatcga caaccttgac tgtgatttca tccccgatgc ggaagacgtt 3317761 gcctgtccgc tcgccaatca ttgcgaaatg ctgttcgtca aagcggtagt agtcatctgt 3317821 cataaagctg acatggacga gtccttcaat tgtattcggc agctcgacga acattccgaa 3317881 gtttgtcaca gagctgatca tgccgtcaaa ctcttcaccg attttatcaa gcatgtattc 3317941 cgcttttttc agatcatccg tctcacgctc ggcgtcaact gcacggcgct ccatagatga 3318001 tgtatgttcg gcgatatccg gcaggcgttc agcccacttt tcctgtgtcg cttcatcgac 3318061 cttgccgttg atcaaatacg ttcggatcag acggtgaacg attaagtccg ggtaacggcg 3318121 gatcggtgat gtgaaatgcg tatagaattc cgttgacaga ccgaagtgcc ccaagctttg 3318181 cgggtcgtat ttcgcctgtt tcatcgaacg gagcataaca gtagatataa ccgtttcctc 3318241 tggtctgtca cgcacagcgt ccagaatgct ttgcagcgcg cgcggatgaa tattccccgc 3318301 cgttcctttc accacatagc caaatgtcgt cacaaattct aaaaactttt gcagcttttc 3318361 agcattcggc tcttcgtgaa tccggtatat aaacgggaca ttcatccaat ggaaatgctc 3318421 cgcaactgtt tcgtttgcta caagcataaa ttcttcaatc agcttctcgg cgacagagcg 3318481 ttctctgatc acaacgtctt taaccgctcc ttcgtcatca acaagcacct ttgcttcttt 3318541 gaaatcaaag tcaacggcgc cgcggtccat ccgcttatcg cgcagaattt gagccagacg 3318601 ctccatgtct ttgaacatcg gaacaagagg ctcgtatttt tgtttcagct cttcatcatc 3318661 atcaacaaga attttattca catctgaata tgtcattctt tccgttgttt tgatgacact 3318721 ttggaagatc tcgtgctctg tcacctgtcc ctgactgtta attgtcattt cacaagaaag 3318781 cgtcaggcgg tcaacctttg gatttaagga gcagatgccg tttgacaatc tgtgcggaat 3318841 catcgggatg acacggtcaa ccagatacac acttgtccct ctttcaagcg cttctttgtc 3318901 aatcggcgag ttttcggtta cgtaatggct gacatcagct atgtgaacgc caagcttgta 3318961 gcttccatca tcaagcttcg tcacggtaac tgcatcatcc aaatccttcg catccgcacc 3319021 atcaatggtg acaatcacct ggtcacggag atcacggcgg tctttcagat ctttttcatc 3319081 aatcgtgtca ggcgtacttg atgcctgttc catcgcgtca gctggaaatt ctcccggcag 3319141 gccgtgctta tgaatgaccg ataaaatatc aatgcccggg tcgtttttgt ggccgagaat 3319201 ggtttcaacc tcaccctctg cgttcatgcg gccttcagga tagctcgtca gcttgacaac 3319261 aaccttatgc ccttccgcag ctccattttt cccatttttc ggaatgaaga tgtcactcgt 3319321 gatttttttg tcgtccggaa tgacaaagcc gaagtttctc gtttctgtat acgtgccgac 3319381 aacccgctga atcgctcttt ctaaaatccg tatgacggtt ccttcctgcc tggagccgct 3319441 tgattgtgag ttcagacgca ccatgacgat atcgccgttc attgccgtat ttagctcatt 3319501 aggcggaata aacacatcac ttaacgacgt atcctcaggc agcaaaaagg cgaatccttt 3319561 cgcatgggct gaaatctttc cttttattaa attcatcttc tccggaatgc cgtagcggtc 3319621 gcttctcgtc cgtacgataa gccctttttc ttccaaggcg actaacgctt tgacgagctc 3319681 tttaaactcc tcggcttccg taatatttaa catctcctca agttcctgaa cggtcagagg 3319741 tttgtacgcc tcttccttca taaacgagag aagcttttcc ataaatgctt ctttttccat 3319801 tatccgacct cctgttgatt accaatcgag cttctctaaa aattcataca catcctgatg 3319861 gacgaggtca cgttctttgt cgagtgtaat gacatgccct gattcctcgt accatttcag 3319921 ctgtttatca tcagtttcca cttcgttgta aataatattg gcgctttcgg tattaatcat 3319981 gtggtcatga cgggcctgca ccacaaatgt cggtgaataa atcatatcga cattattccg 3320041 cacatcagca attaagtctt gcagcgcctt gagggtattc atcggcgttt tttcgaattc 3320101 tttcatttcc tcttcaattt gctccgggct tttcccctca aactttttgt aattgcgagc 3320161 gtatgaaaga acgccttgat acatgacctc ttcactctta atatgcatcg gtgcgcacat 3320221 tgggacaatt ccctttatgg gtacagtgta acccaatttc agcgaaaaaa ccccgccaag 3320281 cgacagtccg caggcagcaa tgctctcata accttcagat tttaaatatt catagccatc 3320341 cattacgttt ttccaccagt cttcgggccc cgtatgtaca agttcttcag gcgggacgcc 3320401 atgtccttca tattgaggcg cgtggcacgt atagccgcgt tcattcaaat atcgtcccag 3320461 catccttaca tccgctgtat ttcctgtaaa gccatgcagc aaaagcaccg ctttgtctcc 3320521 gcctttaaat gtaaatggtt ttggtgtcac aactttcatg ctcatgtctc cctttctatc 3320581 tgcacgatca ttttagtttt ccacagttta atcagaaaaa aacgttttga atatcatcca 3320641 gaaacgtgaa aaaggcctga cttcacatca gaccttatac aaacattgcc ctataggata 3320701 taagcaagcg caatcgttaa cacgaaaaac aagactgcca gcactaccgt aatgcggtgc 3320761 aaaattaaat caagacctct tgctttttgt ttcccgaaga gctgctccgc tccgcctgaa 3320821 atcgcaccag ataatccggc acttttactg gattgaagca aaacgacaat aataagtgca 3320881 atgctgacga taaccaataa ggtaatcaaa actgcgtgca tcccatacac ctccagactc 3320941 actggctaca ttacttctat tttacatgaa aagggttggc atgtcacgct gtatcagacg 3321001 ccaaaaggcc ggataagacg ttttatcttg gttaccctat tcatatgaaa aggtcaaagg 3321061 agaaaagcga tgccgcttat cagcatagac agcaggaaac atctttttta tgaagaatat 3321121 ggacagggaa tccctatcat ttttatccac ccgccgggca tgggacgaaa ggttttttat 3321181 tatcagcgcc ttctatccaa gcatttcagg gtgatttttc cggatttaag tggccacggt 3321241 gatagtgatc acatcgatca gccagcgtct atttcctatt acgcaaacga gatcgcgcaa 3321301 ttcatggacg ctttgcacat tgataaagct gtgttattcg ggtattctgc cggaggctta 3321361 atcgcgcagc atatcggctt cacccgcccg gacaaagtgt cacaccttat tctgtccggc 3321421 gcctaccccg ctgttcataa cgtaatcggc cagaagctgc acaaactggg aatgtatctg 3321481 cttgaaaaaa accccggttt gctcatgaaa atcctcgctg gcagccacac aaaagacaga 3321541 cagcttcgca gcatattaac agaccatatg aaaaaagcag accaggccca ttggcatcag 3321601 tattatctgg attcgcttgg ctacaactgc attgaacagc tgccccgcct agaaatgcca 3321661 atgctgttta tgtatggcgg cctgcgggac tggaccttta caaacgcagg ctattaccga 3321721 agatcgtgca gacatgccga atttttcaga ttggaatatc agggacatca attgccgaca 3321781 aaacaatgga aaacgtgcaa tgagctggtg acagggtttg tgctgacaca tcattcatag 3321841 gaatagaaaa cgcttggctt ccttgcgttt tttgttactt tattgacttt tgtcaacgaa 3321901 atcatagtaa aaaagatcct caaatttcaa attaaaatag tgaagcattt taccaatcac 3321961 aagctgcccc ggccttcttt ctccattcag cacgcggctc agtgtggcgg gtgagactcc 3322021 gatttccagc gcaagctgat taagggaata atcgttatta accatatact gcaagacata 3322081 atcacgtcta atctgtatct tttctactgg cactttcctc accttccatt cctgaaaaac 3322141 ttttttctat acttttacat tacggcttat gttaactttt gtcaatacat ttccagtcta 3322201 cctattccct ttagtcaata aacatactaa aatatgagta acagtgaggg acggggtgag 3322261 atatatggaa agctttggcg aacaattacg ggcattgcgt gaagagagaa agttaacagt 3322321 caaccagctg gcgacttatt caggcgtaag cgcggccggc atctccagaa tcgaaaacgg 3322381 aaaacggggc gttcccaaac ctgccaccat caaaaaactg gcagaggcct taaaaattcc 3322441 ttatgagggg cttatgtaca aggctggtta catcgaagaa gtgcatgaag ccagggcccc 3322501 ttatgaaacg aagtgcaagc tgcttgaaaa agcggaggcc tatgacctga aaaaccttgc 3322561 gcttcttgag aacgaaaagt ggcaatatct caataaagaa gatttgctca tgctggatca 3322621 ttatttttcg tttatttcag atgaagcgaa aaaacggtct gctgatgact gactcttgat 3322681 agaaatgtga ggcgatagac catgtcaccg ttcggacagc aattacggga gctgcgccgc 3322741 gcccgcaaac tgacagtgaa tcagcttgcg gtgtactcag gcatcagctc ggccaccatt 3322801 tcaaaaattg aaaacggcaa acgcgggacg ccaaaacccg ccacgattaa aaaactggca 3322861 gccgtcctga aagtgccgta cgaaaaccta atggccgccg caggccatat tcaggccttt 3322921 cctgaagaaa tccgcgaagc atctgaaggc tatcaatccg tttatgaaat ttaccagacg 3322981 gctgtcacac gcggagcgga gcacctcccg attttcaata gtcaaaaatg ggaacatctc 3323041 tcaaagcagg atattgaaaa tctcagcaaa tacttcgatt ttttgtcttc agaagcaaaa 3323101 aaacgcgcct cttcctcata atcccctgtt tctctttcta tattttatca atcacgcttg 3323161 catgccctcc ctcgttattt gcgttataat agtgacagac gaggtgaaaa gtatgaacca 3323221 atcagaaatg tgtcctagat ttgaaaaagc agtcgacatc ttaagtaaac gctgggtcgc 3323281 tttaatcgta tttcagctct tgaacgggtc gcagcgattt agcgaaattg aagcagcact 3323341 tccaaatcta agcggcagag ttctgtcaga acggctgaaa gaacttgagc ttgaaggagt 3323401 agtgaagcgg gatgtcatcc ctgaaactcc ggttcgcatc gaatattcat tgactgataa 3323461 aggaaaggca ctagcaccca tattaggtga gatttctaaa tgggcgactg aatggattga 3323521 cccttccttt cttgactaat tgctaaaatg gttctgatct caaagacgag aaaagaaccg 3323581 ttttttattt tccaggtgaa aaaaagatat ctcagccgat atatagtaca tccacacatt 3323641 acgtttttaa aggagaccac tatatgcgac tgacgatttc ccgcaaattc agcctggtat 3323701 ttttgacact gatcctgatc aatttacttg taggcggaat aggcgttctt aatatgcagc 3323761 atatcattca aaaaacagat gaaatcaaca caaaatggat tgacggcatc aaaggaatca 3323821 cttcaattaa ttatgtaacc gagcacctgt cttctaaaga aaaggacttt ctgatttata 3323881 cagacaaaag taaaatggat acacttgatc aagaaatgaa tcaaatcatg gaagacatta 3323941 accaaaagct cgataactac gaaaaaacga tctccactga taaagagcag aaactgttcg 3324001 agcagcttca aactaaagtg aatacctata tggatattca tgcgcaaatt atcgaaagcg 3324061 gccgcacgaa tgacatggac aaagcaagag gtttattggt tcagactgag gccagctttg 3324121 aggatatgaa aaaaacaatc actcagcttg ttgacttaaa tcaagaaggc agcaacacag 3324181 cggtaaaaga aacgaaggcc gtctatcata aagggctcat ttacactgct ttgcttgtgg 3324241 cagcatcaat cctcatcagc attttcatct ggctttatat cacgcgaaac attgtaaagc 3324301 ctatcattcg catgaaggaa tctgccaatc atattgccga aggcgatttg tcgaacgata 3324361 tggaggccct caactcaaaa gacgagctgg gtgatctgaa tgaagcgctg caaaaaatgg 3324421 tagggaatct gagagatatt gtcggatatt ctaaagacat atcaagccgg gttctttctt 3324481 cttcacaggt gcttgcaacc gcaacgaatg aaacaagatc cggcagcaaa catattaccg 3324541 agacgatgaa cgaaatggct gagggctctg aacagcaggc ccaagacgcg gtgacgattg 3324601 ccgaatcgat gaatgagttt accgaaagca ttgataaagc ctataatcac ggcatcacaa 3324661 tcagcgatac gtctcaaaac gttctcgaac tcgcggtaag cgggaacgaa aatatggcta 3324721 cgtcattaca gcaaatgaaa accatccatc atattgttga agaagccgtg cataaagtga 3324781 gatcactgga acagcattct caggatatta acaagctcgt tcaggtcatc aacgggattg 3324841 ccgagcagac gaatttgctg tcccttaacg ccgcgattga agctgcccgc gctggagaaa 3324901 gcggcaaagg cttcgccgtt gtggcagagg aggtcagaaa gctggctgac ggcgtttctg 3324961 attccgtgca ggacattacc cggattgtaa acgggacaca gcaggagatc cacactgtca 3325021 ttacgtactt ggaaagcagc tttacagaag tcgaaaaagg aacggaaaac ctgacagaca 3325081 ccggacaggc tatgcagcat atcaaacaat ccgtcaccca tgttgcagac agcattaagg 3325141 aagtaacgga tggcttgaag cagttaacaa accaatcgat taccatcaat caatcgattg 3325201 aaaatatcgc ttctgtatcc gaagagtctg ccgccggcat tgaagaaaca ttttcaatta 3325261 ccgagcaatc cgcccattcg atggatcaag tgcttctaaa tgctgaagag cttgagcagc 3325321 tggccaatga gcttaatgag aagatgggtc agtttacgat ttaaagagaa aaaagaggct 3325381 ggactccagc ctctttttct attctatgca gctgattgaa catgtttcgc cccggttctt 3325441 tttttcttca ccggacttaa tgcccgctcc agccaagcca tgagcaaatc cgcccctacc 3325501 gccatcaccg cagttggtat cgctccggct agaataatcg cagttccgtt tgttgcgttt 3325561 gagccgcgta cgatcatgtc cccaaggcct ccggcaccga caaatgtgcc gatcgctgta 3325621 attccgatgg caatgacgag agccgtgcga aggcccgcca taatgacaga aagtgcgagc 3325681 gggagctcaa ccattctgag cacttggaat ttcgtcatgc ccattgcttt tccagattct 3325741 aagtaggcat gttcaatact gataatgcct gtgtacgtgt ttcgaataat cggcagcagg 3325801 gaatacagaa ataatgatag aatcacggta tttgcgccga gccccataac aagcattaag 3325861 acggccagca tagcgagcgc cgggattgtt tgaataacgt ttgttacggc aaacacccag 3325921 gctgacaaac ggcgaaaatg cgcgatgagg attccggccg gaaccccgac gacagcggca 3325981 aataaaacgc cgtaagccga catgagaaag tggcggccga attcatccat gacgtaactg 3326041 ccattctgcg cgtaatacgt cattaactgt tcaagcacgt tcattgacct cttccccctt 3326101 tcacgattcg aaatagcgat gtttttctaa atattccttg gcaacgacag acggttcttt 3326161 gagattgccg tcgacttcat agttaagctc ctgcatcgtg gctgtgtcga tttttccgag 3326221 cattttcttg atgatgcctt caagttcagg atgttctttg agcacctttt ccggaacaac 3326281 cggagagcag tcgtacggcg ggaaaaattg tttatcatcc tttagcattt tgagaccata 3326341 ggacttgatt cttccatcgg ttgaatacgc aagcacaatg tccatttttc cgcttttcac 3326401 cgcgtcgtac acaaggccga tctgcatcgg atacgtgccg ccgaatgtca tgccgtaggt 3326461 tttcgtaaaa tcctgatagc cgtttccttt gagcttcatc caatagttat caacgcccag 3326521 ctttaattgc ggcgcccatt ttttaacgtc tgatacggtc tctaaatggt attggtcggc 3326581 cagctccttg ctgactgtaa aggcatatgt attatcaaac ccgtaggagt cataccactt 3326641 taaatcatat ctttttttaa actcccgctg agtaagcgcc agcgctttgt ccggatcttt 3326701 ttcaggttcc attctcaacg tgcctgtcag cgcgtctccc gtatatcttg tggccgcaat 3326761 gtcgatttcc ccgttcatta aagcctgctg ctgcaccgcg ttggagccaa gatttttaat 3326821 cgttgttgtt ttgagatcag tatggtgttc gatcaactgg ccaagcatgc tggcgatgat 3326881 ttctgattcg ctcatgcttt gcgcgccgat tttaatggtc tggtctgcag cagcgctgag 3326941 accaggaagc gaacagccgc tcagcgtcag cgttgccgca agtgctaaac ctatcattaa 3327001 tttgagatat tttcttttca tgagccgcct ccttatgaca attccttcaa tctctgcatg 3327061 ccggcaggtg tcagttttcg ttcagcaact gccagcacat aatcaatcac aattgccaat 3327121 atcgtgacag gtaccgcgcc cccgatgata tattccggct gatataaatt cagtccgata 3327181 aaaatgtaat cacccaatcc gccgcctccg ataaaggaag caagcgtggc ccagccgatt 3327241 aagtaaatcg tcgatgttct gattcccgcc atgatcactg gtgcggcaag cggcagctcc 3327301 accaagcgga cttgttcagc cggcgtcatt cctattcctt taccagactc gagcagattt 3327361 ttgttgacgc cgcgaatgcc ggtatacgtg ttgcgaagaa tcggcaatac ggaatagaaa 3327421 aacaaagcca caatggccgg aaccttccct acaccaagga gcgggataaa aaaagcgagg 3327481 atggccagac tcggcagcgt ctgaatgata ttgacaatgc cgataatggt gccggctcct 3327541 tttttcattc tggtaagcac aaccccgagg gggacggcaa ccagcacacc taagatcaca 3327601 gcaatgagcg atatcgtaat atgctcgtat gttttataaa gaagctctcc cccattggtt 3327661 tgcaaaaatt gaacaatatg atgcatgact tatcgcccct ccctatgaca atgctgcgag 3327721 ctgcttttct tctccccaga gggagtcata cacgatgtcg accagacttg ccctcgtcac 3327781 aattccgatc aggcgtcggt cttcatccac aacgggaaca tatttgacac cccgttttaa 3327841 aattttgcgg accgtgtcgc gcagcagtgt gccgcccagt actgtgtata tatcttcatg 3327901 taaaacttca ctgacgagat tggccttttt ccggcattga tcaatgattt caacatcgac 3327961 atagccttgc agaacgcgct cgtcattgac gaccagcaat gaatcgaccc gttcctgcct 3328021 catcagctga atggcctcag aaagcgtttt atccgcggtg atcgttacag gctgtgtgtt 3328081 cataatctgg tcaacccgtt caacatccgg gctggatgac tgaatcagcc gctccttgcc 3328141 gataaattcc tcaacaaatt cgtctgccgg atttcttaaa atgtcatcgg gcgttccaac 3328201 ttgaacgatt tctcccgctt ttaaaatcac aatccggtct gccagcttaa tcgcttcatc 3328261 catatcgtgg gtaacaaata cgatggtttt atgtaaggtt ttttgcagtt ttttaaattc 3328321 ttcctggagg gaatccctcg taatcgggtc gagtgcccca aacggttcat ccattaagat 3328381 aagcggcggc tccgcggcaa gtgcccgtaa tacaccaatt cgctgctgct gccccccgct 3328441 taattcatga gggtaacggt ctacatattc tggccccata tcgaccaatt ttaaaagctc 3328501 acgcgcccgc tctttccgct gctgctccgg ccatttcagc agttttggga cgagtgagat 3328561 attctgctga atggtcatat ggggaaacag gccgatctgc tgaatcacat agccaatttt 3328621 gcgcctgagc tctacaggat cctggtccat gatgttttcg ccgtcaatga aaatcttccc 3328681 ggcggaaggc tcaattaatc ggttaatcat tttcattgtt gtcgtttttc cgcagccgct 3328741 cggcccgata aagcagataa attcgccttt tgcaatctta agatttacgt tgttcacggc 3328801 ttttttgccg cccttgtatg ttttcgagac attttctaat gtcagcaaac atcgcacctc 3328861 caaaattaag tttattcaat ttgttcagtt taaatttaat ttttcagaca attgaatgct 3328921 tcccattata gaataaagtt tataaaataa aaagtttaca atttgttcat attatttata 3328981 aagtatgtgt aaacgctgat ttacccgcat tgacgtgtgt tgatctcctt attgctccaa 3329041 tttcctgcca aattctcttt tgacagcatt ttcgccgtat caaaaatgtg gtatattgac 3329101 atcggaattg ttagctgaaa ggatgaaacc gttggagaaa gatccgttaa cgatcattga 3329161 acaagccgag gaccatttta tagaaagaat cgcggaaaac atgcatgcat ttggaatgcc 3329221 ctctaccgtc ggacgagtgc tgggcattat ttatatgaat cgaaaaccga tgacgcttac 3329281 ggaattatct gaggccaccg gcatgagtaa aacacgtatg agccaggtag tgcgggaaat 3329341 gcttgatgcc aacattgccg agaaggtatt cgaaaaaggc gtgcgaaaag atttatatga 3329401 ggttgagcag gactactatc aaacatttat cacgctgttt tcagccacct ggagcaaagt 3329461 cgtcagcaaa aacaaaatga tgcataaaaa actcaatcgg gagctgctta gcgtgttgga 3329521 tgaagagctt actcctgaag cggaagaaaa agtgaatgag ctgctgaagg aattaaagga 3329581 atggctcgat tattataatt ggctcagccg tttgattgag ttttttgaga gcgaagacat 3329641 ttttaaatat gtgccgaagc cgtaaaaagt tcccaaattc aattctggga acttttttaa 3329701 gtccaatcca aatggttgaa tatcaaactt caagaaaaca aacaaaataa tgcataattt 3329761 acattaattt attaattatc cattttttgt tgattattct gactagctat tatataatct 3329821 ttttgaaatg attatattag cttagaggag gtaatctaca tcaaaaaaaa gggaattatt 3329881 actgtaatga ctatatgttt cctattattt tcttcttatt actttagcaa tatttcacct 3329941 cagaatccac tgttcaaaaa aaattttttg caacaattgt ctccccaagg ctttggcttt 3330001 tatagtaaaa gccctacaga agaaaacatt tcatttcaca caaaagaaaa tttaaagtta 3330061 cctaatgcac ttcccaataa tttttttggg ataaaaagag aaggaagagt tcaggcaata 3330121 gaattaggca aaattgtaga gaatatcgat ccaaagaatt ggaaaacttg tgaaaacaac 3330181 aactcctgca caaatttaga gaaacaaata aagcctatta aggttataaa aaatgaagat 3330241 tatatacatc ttagcaaagg agaataccta atatatcgcc aaaaaccact ctcatggtat 3330301 tggatagact ttaagcaaac tacctctttt gaaagaaagg tgctaaaaat aaaaatagta 3330361 tgaagatatt aaatagttta gaaggttata ttgacaccta taatccatgg aaaaatacat 3330421 atgcactttt tagaagttta cttggtttct caacattact agtactatta ttcaatagta 3330481 ctgatatttt atttagttat agtgcaaata atgtcacatg tgaaaatgtc tatatcccta 3330541 ccgctttttg ttttgctaaa gaatatagta tcaattttga gattataaga tacttaatga 3330601 tttttatatt aaccttagtg gttatagggt ggagacctag atttaccggt ttatttcact 3330661 ggtatatttg ctatagtatt caaacttcag ctttaactat cgatggtgga gagcaaattg 3330721 caactgttct ttcttttctt atattacctg ttacattatt agattcaagg cgaaatcatt 3330781 ggaatataaa gaaaaacaat aatgaatctt tcacaaagaa gacagtattg ttttatataa 3330841 tgacaataat taaaattcaa gtttttatca tttatttaaa cgcagcttta gagcgattga 3330901 aaaataaaga gtgggcagaa ggaacagcaa tttactattt cttttctgat ccggtgtttg 3330961 gattacctga atatcaactt aacttaatga atccactact tgaaagcaat tttattgttg 3331021 tcatcacttg gttagtaact atttttgagt tgttcttagc agcaagcata atttcaaata 3331081 tcagaataaa gagaattgcc cttgttttgg gaatattatt tcatattggg ataatattca 3331141 gcattggtat tgtaagtttt ggcttgatca tgatatcagc attaattata tatctgcatc 3331201 ctgtacaaca aaatatcact atgaattggt gttctccttt atttaaatat atatatgtaa 3331261 aaggaaagag aaatttcaaa agaataggag gtgaatcagt caagtttctt acaaaattgt 3331321 ttcatagcta acatttagat aatggagaaa taacttaatg gaggtataat aatttgaaaa 3331381 gtaaattact taggctattg attgtttcca tggtaacgat attggttttt tcattagtag 3331441 gactctctaa ggagtcaagt acatctgcta aagaaaacca tacattttct ggagaagatt 3331501 actttagagg acttttattt ggacaagggg aagttggtaa attaatttca aacgatttgg 3331561 accctaaact cgtaaaagag gcaaatagta cagaaggtaa aaagttagta aatgatgtag 3331621 tcaaatttat aaaaaaagat caaccacaat atatggatga attgaaacaa tcgattgaca 3331681 gcaaagaccc taaaaaactc attgaaaata tgaccaaagc agaccaactt atccaaaaat 3331741 atgctaagaa aaatgaaaac gtaaaatact cttctaataa agttactcca tcttgtgggc 3331801 tttatgccgt ctgtgtagca gctggatatt tatatgttgt gggcgttaac gcagttgcat 3331861 tacaaacggc tgccgcagta acaactgcag tgtggaaata cgttgccaaa tattcctctt 3331921 cagcttctaa taattctgat ttagaagcgg ctgctgcaaa aaccctaaaa ttgattcatc 3331981 aataatccat tataattgag tgtcttgcgg attgctccgc aagacacttt ttcaacgtga 3332041 accgtttaat tttttgtaat aatgatatga agctagtgtt gaaataacta atgctagaag 3332101 aactagcaca atcataataa gaattatata ttctcctgta aaaaatgaaa gaacagctat 3332161 tataaaacca cacactacaa gtactttaga ggcaaagcga tttcccagtt tccaaacagt 3332221 ctcatctttt aatgtccaag gtgtcctcaa tccaataaga tggttttgtt ctgctagctg 3332281 catagaattt ccaccaataa ttaaaaagat accaacacca agccctatta ttaaatcaat 3332341 attcacttcg tatcctaaac ttatcaatag agttgagagt tgtaaaatat ataaaaggat 3332401 taacatatta ttagaagcta ggaaaagcaa tgctttattt ttttgtgtag acttaatagt 3332461 taacatataa aaagtaagat aataaataag cataacaaca ggtataataa atattgttaa 3332521 aggtttagat acaattgcag ccggtttatt tcctgaccat tgtatcggta tttcttctgg 3332581 aaggtattga tataatataa ttgaagtcaa gaaactcaaa catacaataa ttatggaaat 3332641 tatatttttc ttcataaatc gttatcccct ttatttataa agttaagcat ccaatttatt 3332701 gagtcttgaa gtactgttgt atttagagag taataaataa attgtccttt gcgatggtca 3332761 cttatgactt ccgcttgctt taaaatattc aagtggtgcg aaatactcgg tttgctgata 3332821 ttaaaatgct cagcaatatc tcccgcagtc atatcccctc cttttaacaa atccaaaatt 3332881 tttctccttg ttggatctga tatagctttg aaaacattat tcatagcgtt ttctccttta 3332941 caaaaaaaca tttagacatt tagatatttg tataaatgta ttattttcat tataacttga 3333001 atttttttaa aaacaaccct caaattggtt ataatatctg atttttgtat tttttcaaat 3333061 actcggataa tcccaacgct ggaaaatatg tttaacagat actaacacat gttgtttatt 3333121 taaaaaaacc acctctgttg tatttaaata gaggtggttt ttctatcagc tataataaaa 3333181 tttccttttt tctttttaat cgggcttaat gctcgttcaa gccagcccat gaccaaatcg 3333241 gcaatcaccg ccatcagagc tgtggggatc gctcccgcta atataatcgc ggttccgttt 3333301 gtggcgtttg atcctctgac gatgatgtcc ccgagaccgc cagcaccgac aaatgtcccg 3333361 atggccgtaa tgccgatcgc aatgacaagc gcggtgcgca ggccggccat tatgacagaa 3333421 agcgcaagcg gaagctcgac catccgcagc acttgaaatt ttgtcatccc cattgctttt 3333481 cccgattcaa gataggcgtg ctcaatactg ataatccctg tatacgtatt tctgataatc 3333541 ggcagaagag aatacagaaa taatgacaat atcaccgtat tagcgcccag ccccatgaca 3333601 agcatcagca cggcgagcat ggcgagagcc gggatggtct gaatgacatt cgtgaccgca 3333661 aaaacccatc cgcttaatct tctgtatctg gctatcagga tgccgagcgg aattccaaca 3333721 atggcggcaa ataaaacgcc atacaccgac atcagaaaat ggcggtaaaa ttcctgcagc 3333781 acgtaaccgc cgttttgcga atagtatgtg ccaagctgct gtagtacttc catatgatcc 3333841 acctcttttc ttagtcaaaa taatgatgtt tctctaaaaa ttcctttgct acgacagacg 3333901 gctccttcag cttgccatcc acctcataat taagttcctg catcgtttcc gtgtcgattt 3333961 gcccaatcag cttattgatc acaccttcaa gttccggatg ctccttaagc accttttccg 3334021 gaatcaccgg tgaacagtca tacggcggaa agaaacgctt atcgtctttt aagattttca 3334081 gatcatatgc tttaatccgt ccatccgttg aataagccaa aaccgcatcc attttcccgt 3334141 ttttgactgc gtcatagact agcccgatct gcattggata agttgtgccg aactcaaagc 3334201 catatgtgct gacaaagcct ttatacccgt cgccttttcg tttcagccaa gcattgtcga 3334261 cgcctaattt atattgggaa gcatttttct tcaggtcaga cacggtgtta atatgctcct 3334321 tttccgcaaa cttttttgtt acggtgaagg catatgtgtt atcaaagccg taggaatcaa 3334381 accatttata agaaaagcgc ttttgaaact cgttctgcac aatgttcagc gcttttttcg 3334441 gatctttctc cgcttccttg ccgagggtgc ttgttaaatc tgttccggaa tagcgcgtgg 3334501 ctgaaatatc aatgtcaccg cccagcatcg cttggtgctg aacatagttt gagccgaggt 3334561 ttttcactaa agcagtattc aaatctgtat catgttcaat aagctgcgcg atcatattcg 3334621 ctacaatttc tgattctgtc atgctctgcg ccccgatttt gatcgtatcg tcagaagcgc 3334681 cgcctagacc cggcagagag cagccgccta gcagcatgac aaagacgaga gcaaacgcgc 3334741 caagccattt gatttttgtc attttcaaca gtgccaactc cttacgatac ttccttcatc 3334801 ccttgcaagc ctttcggcgt cacctttcgt tctgtcacag ccagaacata atcaataata 3334861 attgccagaa ttgtgacagg cacggcaccg ccaatgatat attcaggctg gtataggttc 3334921 agtccgataa aaatatagtc cccgaggccg cctcccccga taaacgacgc aagtgtcgcc 3334981 cagccaatta ggtagatcgt tgatgtgcgg atccccgcca tgatgatggg aatcgccagc 3335041 gggatttcaa cgagccgaat ctgctcccag ccggtcatgc caattccttt ccccgattcc 3335101 aggaggtttt tatttacacc tttaatgccg gtatacgtat tgcgcaggat cggcagtacc 3335161 gaatagaaaa ataaagcgac aatcgcaggc acttttccta cgccgagaag cggaataaaa 3335221 aaggctaaaa tcgccagact cggcagggtt tgcacaatgt ttacgaaacc gataaccgca 3335281 cctgcgcctt ttttcattct ggtaagagca acgccgagcg gcactgcaac gataatgccc 3335341 aatacaacgg ctatgagtga aatatataaa tgctctcctg ttttatacag cagctctccg 3335401 ccgttcgttt gcaaaaaagt catcatttga ttcatcttaa aagagctcct cccctggtca 3335461 gatcgtcatg agctggtttt cctcgtcgcc ccaaatggaa tcgtatacga tatcaacgag 3335521 gctcgctctt gtcacaatcc ctgctaaatg gttctgttca tcgaccaccg gaacatactt 3335581 gatcccctgc ttcaaaattt ttcggactgt atcgcgaaga agcgcccctt tttgaacggt 3335641 atatatatct gaacggtata catcgccaac gatgctcgct tttttgcggt tttgatcaat 3335701 catttccaca tcaacatagc ccttcagcac gttttgccgg tccacaacga gcagcgagtc 3335761 aacacgtttt tctctcatca gctgaatcgc ctgagaaagc gttttgtccg cagataccgt 3335821 caccggcgtt ctgttcatca tttgctctac ccgctcgata tccggtcttg actgaatcag 3335881 gcgctctttc ccgataaatt cttcaacaaa ctcatttgcc gggtttcgaa gaatctcatc 3335941 aggtgtgccg acttgaacga tttctcccgc ttttaatatc acaatcctgt cagcaagctt 3336001 aatcgcttca tccatatcgt gggttacaaa cacaatcgtt ttgtttaagg ttctctgcag 3336061 ttttttgaat tcttcctgaa gggaatcacg cgtaatcgga tcaagcgctc cgaacggttc 3336121 atccattaaa atgagagggg gttccgctgc cagggcgcgc agcacgccga ttctctgctg 3336181 ctgtccgccg ctgagctcat gcggataacg gtctaaatac tctgggccca tatccacaag 3336241 ctttaacagc tcgcgcgccc gttctttccg tttttcctca ggccatttca gcagctttgg 3336301 tacgagtgag atgttctgct ggatggtcat atgggggaac aaaccaatct gctgtatcac 3336361 atagccgatt tttctcctca gctcaaccgg gtcctgttcc ataatatttt ctccgtcgat 3336421 aaagatcctt ccagacgatg gttctatcag tctgttgatc atcttcatcg tcgtcgtttt 3336481 tccgcagccg ctcgggccga taaaacagat aaattcacct tttgcaatat ctaaatcaat 3336541 gctgttcaca gcttttttgc cgcctttata tacttttgac acttgttcca atttcagcaa 3336601 tccgtgcacc tccgcaggtt tcctttaaat tttctgaaaa gtataatcct tattatagtt 3336661 tgaactttgt aaaataaaaa gtttacaatg tgttgaaatt atatgttatt tatagattat 3336721 ttattgttat gaccgagacg gaaagggtgt tcttacaatt actccggata cctcccactt 3336781 cctctgcatt cagctatttt caacaccagg aagaaatatg atatattgac accatcaatt 3336841 gccatttgaa gggatgatca gctgtgaaaa aaaccgctct cgacatcatt gaacatgctg 3336901 aagagcatct cattgagaag attgccgaaa atatgcatac gtttggaatg ccttcaactg 3336961 tcggacgtgt gctcggaatt atttatatga atcgaaaacc aatgacctta agcgagctct 3337021 ctgaggcaac gggcatgagc aaaacacgga tgagccaggt tgtccgggaa atgatcgatg 3337081 ccaatatcgc cgaaaaggtg tttgaaaaag gcgtacgaaa agacctttat gacgtcgagc 3337141 aggattatta tcaaaccttc atttctttat ttgcggcgaa ttggacaaag gtcgtgagca 3337201 aaaacaaagt gctgtataaa aaattaaacc gggagctgag tgatctttta caaagggacg 3337261 ggcttacccc ggaagcggaa gagaaagtca atcagctgct gaatgaatta aaagaatggc 3337321 ttcattacta tgattggctg agcaggttga ttgaattttt tgagagtgag gaagtctttc 3337381 ggtatgtgcc gaaaacaaaa gaatgcagct ctctaaaata agagagctgc tttttgcatc 3337441 atgaagttaa gaccggaaac atgcctttca gcccggcacc aatcatcccg accgcaacca 3337501 cggctaagat taatcccatc agtctggtaa tcacattcat ctcggttttt ccgagtttgc 3337561 tgctgataaa agcagaatag tggaaaaaga gaaaggtcag ggcaataacg gcggctatgc 3337621 cgatcatgac agccgcataa tgaccaatgc cgctatgtcc ggcggaaagg ctcatcactg 3337681 ttgcaatcgt tccgggccca gcaatgatcg gaatggataa aggtgtgact gatatatccg 3337741 ctttttcctt gctttcctta tgttcatcat ggtgaagaga ttgcacgtgc gattctttcg 3337801 cattcaatag attataggca atgccgaaaa tgaatatgcc gcccgccact cggagcgcgt 3337861 gaatgttgat atcaaacagt ttaaagataa gatgaccgaa aaccaaaaaa gctgcgagaa 3337921 taaaaaagga taaaatagct gccttccggg caatcgcttt tctttccgct gcagtatagc 3337981 cttctgtcag cgtcagaaat atcggtacgt ttccgatcgg attcgatact gcgaataaag 3338041 aaatgaagac gtgaacgata aatgagaaca tcatatacct ccttgttgat agtctctgca 3338101 caggaaatag aatgattctc caccctttta cccggaggcg atttcccggt aaacctttat 3338161 agcctgtcag aaacgcgcca tgctacaatg aagtgacaaa ttgaatagga aggacgtata 3338221 cagatgttca aaaaaattgc ggcagatgcc ttgggcttat ctgatatcgg aaaaattatc 3338281 gaacctcagg actatgacaa aacagacgca gatgactatg tcatgcatga agataatgag 3338341 aaaatttatt tcttgattaa aacaaaagca gacgagtatt gctttacgaa cctggccctg 3338401 atccatgtgg acggcgaacg cgccacttcc tcaaaacgaa cgttgaaacg ctatccttat 3338461 tcgcaatata aaatctctga cgtttttctt gaaactgccg gaaaagtgga tttggatgtt 3338521 gaaattaagt tcaagctggg cggtgaacaa ttcgacattg atgtccacaa agaccagatt 3338581 gaaaagttaa aagaccttta taaagcactg cttcgcatcg ctgaaacaac ctatgaaaat 3338641 gacattttaa tcaatcaagc ggagcaaagc ttagataaag cagtgacgat tcttcaccat 3338701 acccgccctg agcacgtcaa tattgaaacg caatacaaag agctgaccga attcggattc 3338761 acttggctga catccgttcg ctcgcagtat catattaagg attttgggga tgtatttgag 3338821 aaatatatta ataactagat aaaaaaagac acagctgcta tcgtgctcgt gtcttttttt 3338881 gtatgaatat tgattacttt acaacttttt tcttttataa taaaactatt agtctatttt 3338941 ccctatatta cagataaagg agttatttta tgtattgtcc tcaatgcggc catcaaacag 3339001 atggcggaaa tttttgtgag aaatgcggat caccgctccc cggtcaatca ggccaccagc 3339061 atgcagctca aactggagcc gctgcaaagc aagcagcaaa acagttcggt tcatttgtct 3339121 tatccgtcct gaaacgccct tatcaggaat gtaaagcaac aggcggagaa cagctgatca 3339181 gcgcaatcat tacgatggtt cttttcagtt tgctgacccc tttgatgttt tatattcttt 3339241 tttcagacgg tcccggaagc gtaagcttta cagcaatctt cttagagcca accatttatt 3339301 ttattttatt tctatttggc ctgcatgcat gcatcttttt cgccctgaaa atcgcgggaa 3339361 accaagtgtc tttcaaggat tcattctcaa gattcggagc atttcttatt ccttttacgg 3339421 ctattttgat tcttgccctt ttcttctttt tattacatac agacatttgc tttaccatat 3339481 tagccgttgg tttaatcggt gcattcttcg ccattcctcc tgcgatgctg agcagttacc 3339541 agcattcata taaagggaag gttgatttca tttactcaac gattgtgatt tatctgatca 3339601 tctgcgttac atttcagctt attatcgaac actatgtcaa agaaattttc cgttatatgc 3339661 tcttttaaaa acaaccccat cacctgctgg tgatggggtt gttttattga atagacgtta 3339721 agtaaattct tccgttcttc actacgccgg tgtaggtcca gttatatgtt ctgagctttg 3339781 gactgccgcc tgattttgtg atatagaatt cttcatacgt cttaatcgtg atagccgacc 3339841 cattttggct ccagcttttc acttcatagt tattaaagtc ttctgttgtc ccctctttat 3339901 ttaatttcga cacgagatgc tgctggtcgg aataaaggga actgcctttt tcaaggctgt 3339961 cttccatcag tgagaaatta ttttgattca cggcatctgc ctgactttgc agataactgc 3340021 ccataaataa tgtcacttgt tcatctgtaa catcgccgct tgcagagctt tcactgcctt 3340081 tgtttttcga gccagcccag gcggaagtgt atgtctctgg tttatcattt ttgattttct 3340141 ttatatttgt gcctgcagat tcgaatgttg attctgcatc ttcgaaaatc cactttttct 3340201 gttttttatc atatgaaaga agatattcat aactcggact gtcgtcagtc atttcagact 3340261 ttgtatagtc gttatacgaa gaagactggt gaagttcttt tcctgttacc gatacctgcc 3340321 acgttccgtc gtttttctga gagagggcaa atgtgtccag gtcaaaatca gtttccaagt 3340381 atctatcttt taagtatgaa tccgcgcttt tcatagaatc gacggtgtcc ttcgtctccg 3340441 ccttccaatt ggcacttgcc tctgtcatct gggctgtatt cccatcagat agagctttgg 3340501 agtattgttt tgttgttttg acaattgtgt tcataatctg ttcctgtgta tcttgatcag 3340561 gaattaacgt taactccatt tctttatcat cgatcggaac gccggcagtt tttgtttttc 3340621 cccacggaaa ttctgcctcg actgaagctg tcattgatcc atctgtcagc agcggaccat 3340681 atgttacgga tttgaacgga tctttatgaa ttgatttacc gttaatcagc aaatctccct 3340741 tcccgctctt gatgtcattc gctaagctga atgtcacatc gtctgcttcc aatgagagat 3340801 caacacgaaa gctgctatcg ccaatcgcct gaatgtcttc ctttttcaca aggtcaacga 3340861 catcgttttt cagtttggct gagactgtat attcgccggg aatgtacgga ccaagggttt 3340921 gtgcttgatc tgctttcttt acagatccgg cttcctcttt attgacatat agatcggtat 3340981 ttttataatt gctgctcact tcaaaataaa caggtgctac ctttaagtca taatggtcaa 3341041 ataccagcag gcttttcccg tctttttccg catatacgat atccttctgg gctgtttcat 3341101 cacgcagcga tgcaaaaagt tcatcttttt tgtctggatg atccttcaaa tatgtaagaa 3341161 acggttttac attattttta gtgagtttaa gattgtcatt taccggtgta agcagagtcg 3341221 cgatttggtc ctgatcccca tcatttacgg cctgttcaaa cttgtctact aacctatcct 3341281 ttgaagtaaa atacgctccg gttttatatg cggcgaataa tataacgcac gccgcggcaa 3341341 tgctgctcca taaaatgatg gttttcttag ggatcggttt tcgcggagcc tgcctcgttt 3341401 ctgcagtgct agctgtttct tgatttgcct gtttgctgcc ccctccgatc ggggtgccgc 3341461 attgtttaca aaacttggct ccttcattat tctgggagcc gcaattctta caaaataaca 3341521 tgactttcct cctattctac taatttgata acatttactg cttttcatat tttataataa 3341581 aacagaatga aattgggaac gaatgaaaaa attaaatgtc tatcagacta aaaaggtgga 3341641 atgaatatgc aaaagctcag gattgaatta ggagaagaaa caaatgacga attatatgat 3341701 ctattgctgc tcgccgatcc atcgaaagac attgtagatg aatatcttga gaggggagaa 3341761 tgttacacag cttgggccgg tgatgagctt gcaggggttt atgtattgct aaaaacaagg 3341821 ccgcaaacag ttgaaattgt aaatattgcg gtaaaagaat ctcttcagaa gaaaggcttt 3341881 ggcaaacagc ttgtacttga cgccatcgaa aaagcgaaga agctgggggc ggacacgatt 3341941 gaaatcggaa cggggaattc gagcattcat cagctttccc tctatcaaaa atgcggattc 3342001 cgcattcagg cgatcgacca cgatttcttt ctcagacatt atgatgagga catttttgaa 3342061 aacgggattc aatgccgcga tatggtaagg ctttatttgg atctctgaaa gcataaaaaa 3342121 gccgccgaga gaaaatcccg gcggtctttt tattacttgt ttaagttgta gaaagagttg 3342181 ataccgtggt attgagcagt ttcagccaac tgatcttcga tgcgaagaag ctggttgtat 3342241 ttcgcaacac ggtccgtacg agacggagca cctgttttga tttgtcctgc gtttgttgcc 3342301 acagcgatgt cagcgattgt gctgtcttca gtttcaccag aacggtgaga gataacagct 3342361 gtgtagcctg cgcgtttcgc catttcgatc gcatcgaatg tttcagtcaa tgtaccgatt 3342421 tggtttactt tgatcaggat agagttgcct acgccgtttt taataccttc agaaagtttt 3342481 ttcgtgtttg taacgaagag gtcgtcacca acaagctgaa cttttttgcc aagacgctca 3342541 gtaagaagct tgtggccttc ccagtcgttt tcgtcaagtc cgtcttcgat cgagatgatt 3342601 gggtatttag aaacaagctc ttcataccag tcaaccattt cagcagatgt tttcacaacg 3342661 ccttcgccag acagatggta tttgccgtct tctttgttgt agaactcaga agatgcagca 3342721 tccatagcaa gtttaacttc ttcgccaggt ttgaagccgg ctttttcgat tgcttcaacg 3342781 attgtttgaa gcgcttcttc gttagaacca aggtttggag cgaatccgcc ttcgtcacct 3342841 acagcagtgt ttaagccttt tgcgcttaat actgatttca ggctgtggaa gatttgagcg 3342901 cccatgcgaa gtgcttcacg gaagttagga gcacctacag gcatgatcat gaattcttga 3342961 atatccacgt tgttatcagc atgctctccg ccgtttacga tgttcatcat cggtacagga 3343021 agcgtttttg agttgaatcc tccaaggtat tggtaaagag gaatctgtaa gaaatcagca 3343081 gcagcacgcg cacaagccat agatacgcca aggattgcgt tcgcaccaag tttgcctttg 3343141 ttttcagtac cgtcaagctc gattaaaagc tgatcgattg cgttttgttc agttacatca 3343201 aagccaagaa gctctggagc aatgatttcg tttacgttgt taacagctgt taacacgcct 3343261 tttccaaggt aacggtcttt gtcgccgtca cgaagctcaa ccgcttcgta ttcacctgta 3343321 gaagctccgc ttggcactaa tgcgcggccg aaagctcctg tttctgtata tacttcaact 3343381 tcaactgttg ggttgccgcg ggagtctaat acttcgcgtg cataaacatc aacaatgtat 3343441 ggcatgagtt ttgtctctcc ttttgatttt caaattattt ttgaattaaa gatgttcctg 3343501 tcatttcttt cggtttttca acaccaagaa ggtctaataa cgttggtgca aggtcgccta 3343561 ggattccgcc ttcacgcagc gtaatgcctt ctttcgttac aatcacaggg actgggtttg 3343621 ttgtatgcgc agtgtgcggt tcgcctgatt ctgtaatcag aatgtcagca ttaccgtgat 3343681 cagcggtaat gatagcgtgt ccgcctttag caaggatcgc gtcaacgact tcgcccaagc 3343741 attcgtccac tgcttcaatt gctttaattg ttggttcaac cattccggag tggccgacca 3343801 tatcagggtt tgcgaagtta agaatgatcg cgtcatgctt gtcagcttca atttctttga 3343861 caagcgcgtc tttcacttca tacgcactca tctcaggctt caagtcatac gttgcaactt 3343921 taggcgagtt gatgagaata cgctcttcac ccgggaattc agcttcacgg ccgccgctca 3343981 taaagaacgt gacgtgcgga tacttttcag tttctgcaat tcgaagctgt tttaacccgt 3344041 gctgagataa tacttctccg actgtgttat caagatttat cggtttaaac gctacatagc 3344101 cgtcaactgt ttcactgaag tgagtcaggc agacgaaata caggttcttt ggataattct 3344161 cgccgcggtc gaagtcacgg aagtctttgt ttgtgaacgt gttggaaatc tggatggcgc 3344221 ggtccggtct gaaattatag aaaatcacag aatcgccgtc ttggattttc gcaacaggct 3344281 caccgttttc ttttgtgatg acagatggaa tcacgaattc atcgtagata ccatttgcat 3344341 atgaatcatc aacaacatcc agggcgctgc ggtaagatgg gccttcgccg tacgccattg 3344401 cgcggtacgc tttttctaca cggtcccagc gtttgtcgcg gtccatagag tagtaacgtc 3344461 cggaaatgct ggcgatttca cctacaccga tttccttgat ttgatcgttc aactggttga 3344521 tgtacgtttt cgctgtctgc ggacctacat cacggccgtc aaggaagcca tggatataaa 3344581 cctttgtcag cccttctttt ttcgcaagct ttaacagtgc gaataaatga ttgatatggc 3344641 tgtgcacgcc tccgtcagat aaaagaccga acaggtgcaa ggctttgttg ttttctttcg 3344701 cgttgctgat cgcgtcaagg aatgtttgat tgcgttcgaa ctctccttca cgaatggcaa 3344761 catttacgcg tgttaagctt tggtacacaa tacgtcccgc accgatattt aagtgaccta 3344821 cttcggagtt ccccatttgc ccttcaggaa gacctacagc ctcgcctgaa gcagtcaaag 3344881 tttgatgagg atactggttc caatagcggt caaaattcgg ttttttcgct aaagcgactg 3344941 cgttccctac tgtttcgtta cgtaatccga acccatcaag aatgatgagt gcagctggtt 3345001 ttttactcat attgaccttc ctccaataat tgaacgaatg actgtggctc aaggctcgcg 3345061 ccgccgacca aagcaccgtc aatatcggac tctgccatat attctttaat gtttgcaggc 3345121 tttacgcttc cgccatattg gatgcgaagc ttgtctgcag cttcttggct gaagctttca 3345181 gcgacggttt tacggatatg cgcacacacg tcattcgcat ctttcgctgt agaagatttg 3345241 cctgttccga ttgcccagat tggctcatac gcaataacag aagcagcaac ttgttcttca 3345301 gaaagaccag caaggccttt tttcacttgg tcagcaacaa gatcatttgt tttgccggct 3345361 tcacgctctt caagcgtttc acctacacag atgatcggca caatgccgtg tttgaaagct 3345421 gcgtgtgctt ttttgttaac tgtttcatca gtttcagcga acatttcacg gcgctcagag 3345481 tggccgatga cgcagtagtc aacgccaagg tctttcagag caaccgggct gatttcgcct 3345541 gtgaacgcgc cgctttcttc gaagtgcatg ttttgagcgc cgacttttag gtcagtgcct 3345601 ttcacagcag aagcaagctt ttctaagaaa agcgctggcg cgcaaacaac agcttcagct 3345661 ttgtctgctg ctggaatgga agatttcact tcttcaacga agctgacagc ttcgccgagt 3345721 gttttgttca ttttccagtt accggcgata attggttttc tcatctgttc cacttcctta 3345781 tagcagtttt gagattattt atcgttcagt gcagctaccc ctggaagctc tttgccttcc 3345841 ataaactcaa gggatgcgcc gccgcctgtt gagatgtggc tcattttgtc agcaaggccg 3345901 aatttttcaa ccgctgccgc agagtctcct ccgccgatga cagagtatgt atctttcgcc 3345961 tctgccaatg cttccgcaac cgcttttgtt ccttgagcga acaagtcgat ttcgaatacg 3346021 cccattggtc cgttccacac gacaagtttg ctgtttttga tgacgtcagc atacgtttcg 3346081 cgtgttttcg taccaatgtc gattgcttct aaatcactag ggatttcaga gatcggcaca 3346141 attttcacgt ttgcatcgtt agagaaatca tctgcaacga gtacatcttc aggcatgtag 3346201 aagttaacgc ctttttcttt agcgcggtcc ataaatgatt tcgcaagctc gattttatcc 3346261 tcttcaagaa gagatttccc gacttcatag ccaagcgctt ttacgaaagt ataagcaaga 3346321 cctccgccga tgatcaggtt gtctacttta tcaagaagac tttcgattac accgattttg 3346381 tcttttactt tcgctccgcc gatgatcgct gtgaacgggc ggtcaggatt ggaaaccgct 3346441 tttccaagta catcaagctc tttttccatt aagaaacctg caactgctgg cagatgctcg 3346501 gcaattccag ctgtagatgc gtgagcacgg tgggcagcac cgaatgcgtc atttacatat 3346561 acatctgcaa gctcagcaaa tgcttttgca agctcaggat catttttctc ttcaccagga 3346621 tagaaacgta cgttttccaa tacaagaacg tctccgtcct tcatctcaga aatttgtgct 3346681 tttacagcat cgccgtatgc ttcatccgct tttttcactt ctttgccaag cagttcgccg 3346741 agacgtgcag cgacaggagt taaacgaagc tcctcaacca cttcgccttt cgggcggcct 3346801 aagtggctcg caagaaggac ttttgcgcct tggtctgcaa ggtgtttgat tgttggaagc 3346861 gcagcacgga tacgtgtatc gtctgttact tccccgtctt tcattggaac gttaaagtca 3346921 acgcggcaga atacaacttt gccttttacg tcgatgtctt tgagagtttt tttattcatg 3346981 cctaggagat cctccttcaa aatggtttgc atacagcacg aaaaacgtga aaccgtctgt 3347041 tcaagcgata actccgctag ggcagatcgc agtctttttc ggcacagggc agttcgtcta 3347101 aaagccaggg cagcggcctt aggcgaaagc gccggcaaag ctgcttaaaa cgcggtcgtt 3347161 tctctatcac agagcgtttt ctgaaagccg gtcttcatgg aaaaagggaa agggagtccg 3347221 tccccttccc ttgtccgctt tcattatagc gcttctattc gaaagaacca agtcaggtcc 3347281 tttttcagct ataaattaaa gacctttttt tgcgatgtaa gctgcaaggt caacaacgcg 3347341 gttagagtag ccgctttcgt tatcgtacca agagattact tttaccatgc tgccttccat 3347401 aaccattgta gaaagagcat cgattgtaga agagtttttg tttccgttgt agtcgccaga 3347461 aactaatggc tcttcgctgt agccaaggat tcctttaagg tcgccttcag ccgcttcttt 3347521 aagagctgcg tttacttctt cagctgttac ttcttggttc agttcagcaa ccaagtcaac 3347581 tagagaaacg tttggagttg gaacacgcat tgctccaccg ttcagtttgc cttttagttc 3347641 aggaagaact agagaaactg ctttagcagc accagttgat gttgggatga tgttttcagc 3347701 tgctgcacgc gcacgacggt agtctttgtg cggaagatca aggatttgct gatcgtttgt 3347761 gtaagagtga acagttgtca tcataccgcg tttgatgccg aatttatcgt taagtacttt 3347821 tgcaaacggc gcaaggcagt ttgttgtgca agatgcgtta gagataacat cgtggttagc 3347881 cgcatcgtat ttatcttcgt taacacccat aacgattgtg atatcttctt cgttagcagg 3347941 agcagagatg attacttttt tcgcgccagc ttctaagtgt ttcgcagcgt ctgcgcgttt 3348001 tgtgaagaaa ccagtagatt caactacgat ttcaacgcct tgtttgcccc agctaagttt 3348061 agcaggatcg cgttctgcag aaacttcaat tgttttgccg ttaacaacaa ggttgttacc 3348121 gtcaactgaa acttcagcgt ctaattttcc gtgtacagaa tcatattgta aaaggtgagc 3348181 cagcatgtta gcatctgtta aatcgttaac cgctactacc tcaacttcag gattgtttaa 3348241 tgctgcgcgg aatacgttac gtccaatacg accaaaaccg ttaataccga cttttactgc 3348301 catgattgtt tcctccttta aataagtgag agatatttat attgagggat tattcatccc 3348361 ttaataactt ctttgcggct ccttcgtctg tgacgagaac cgtgttgcgt ggctttttaa 3348421 agtaagcctc gatcgcttcg gcttttgatg atccgcccgc taccgcaata atatcgggga 3348481 tggcgtctat gtcatccagc tgcattccga cagaatgcac tttgtgaacc acttcgccgt 3348541 ccgcgttaaa atagtagccg aacgcttccg tcaccgcgtc gttatcatct attttcttta 3348601 aatcttctaa aggcgtgttt ctgcgctgag ccatagtttt agcttcgccg attccgtgaa 3348661 ccagcatact cgctgattta atggtgttca gcacctcttt gacagaaggc tcttcaataa 3348721 tagatgaata ggcgccttgt gacagctgtc ccggaacaaa caaaagccgg taagtgcctg 3348781 aagccttctc cgccatatgc gcgcatatgg tgttcgcctg gtttttcacg tcttcgccta 3348841 aaccgcctct tgcaggcaca aacaaaagct cgcggttttt agaatccggc gtcatcattt 3348901 cggcgacagc ttcaattgtc gtaccgccag ttacagcgac gatatttttg cctgaaaatc 3348961 tttttttcat acatgcgaca gccgctcttc ccatttcttt tttgacccat ggggattgat 3349021 cgctgtctcc ggatacgata atggcatcct ttagatttaa acgttctttt aatgtctttt 3349081 ccaaaagagt caaacctaaa acatctttca tcgtatcttc caaaacagaa agcagttcat 3349141 agccctcttc tgtcaatgtc atgccgtttg tcttaatatc gaccaggttc tgttccttta 3349201 aaaactgaac ctcgcccctc agcacacgct cgctgattcc gagactggca gacaggcttc 3349261 ttcgcccgat gggttctgtc agcctgatat actgcaagat ttcaaacctc ttttgcataa 3349321 cgagcagaag atcaggcaat aatttttttt gagcttgtat taactggttc atgactcaaa 3349381 cgttccttcc ttttttgctg gacattatat gtcccgctat gacaaaaaac gtcccgtcat 3349441 agccaaaaaa aatcatttct gctttcttta attattttaa cagggtggaa ttgtttattc 3349501 aactgttaag agccaattca tcgacaatat tcgcagagtt ttcatgccgc gtcgttttat 3349561 ccagcaatat tttatcctat atatctttat cttatacaga aagcgccaaa tggtgcatcc 3349621 caatataaac agcccttccc gtagaaaggg ctgtttcatt aaagcgtttt cattttatcc 3349681 aaagcttttc aatttcctcg agcgatttgt tcttcgtttc tggacagatc gtaacgacaa 3349741 acaggaaaca aaggatgtta atcaccgcaa agatccaaaa tgtataggcg agcccgaaag 3349801 aatcgatcat cattggcaca aactgtccga tcgcccagtt tgctccccat aaaaagatgg 3349861 tcgcaatgcc cgcggcccgc gcacgcagat ggttcgggaa gatttcagaa atcataatcc 3349921 atgtgatcgg tccgaccgag acacagaaag cagcgacaaa acctaatata aggacgatca 3349981 tcatgatccc gcttgttaac tcaaaataaa acgacgtccc gattaaaatc ataaaaatag 3350041 ccataaaagc agaaccgatg gacatcagtt tttttcgtcc gactttatca atcagcaaca 3350101 ccgcaataac ggtaaaaata acttctacaa ccccgacgat acaagtcgtc acaaatccgg 3350161 cgttttgccc gaatcccatc attttaaaga tttccggccc gtagtaagta atcgcgttca 3350221 tgccgatgac ttggttaaac agcgccagca ggattccaat gacaagcgcc tttctgagac 3350281 ccggcttaaa cagctgggag agcgacccca tttgttctat ttttaaagag ttctcaatgt 3350341 tctttaattc ttcttttgca acagtttctc cattaatacg tgtcaggatc tttaaagctt 3350401 catttgtttt gcccgctttc gccagccatc tcggactttc cgggacgacg agcaggacaa 3350461 ggaaaaaaat gacggatggc accattccat aagcaagcat ccatctccag ccggtgtgca 3350521 cgccccattc gtatgttccg gaccgctgca cagctagatt aataaagtat gttgcggaaa 3350581 tacccagtat cgtaaagagc tgatataacg aagataaact tccgcgtata gcgggcggtg 3350641 ccgcttctgt aatatacgta acagagagcg atgagcccat cccgattccc agccccccga 3350701 taatccttgc aatgattaag gtggacacgt cttgagaaag cgctgaaacg attgctgata 3350761 tcgcaaataa caaagcggct gtcattaaaa tttttctccg gccgaatctg tcacttaaaa 3350821 atccggatat cccgacgccc acaactcctc caatcataat gcttgaaatg acaagtccct 3350881 ccataaacgg actcaggctg tataaatctt tcagaaaacc gatggcgcca gaaatcactg 3350941 ccgtgtcata gccatacaat aagccgccaa gccccgccgc acatgagatc aaaatgacaa 3351001 atcccattga atggcttctt gttacaggaa catttggttc taattgagtt ggagtattct 3351061 tcatttccct gccctcccga atgttgagta aagcgttttc atttaaacct tcaattgtac 3351121 gtacttatat taaaatttaa cgaaaattac atttaattag tacgtacaaa tatagaataa 3351181 tcttgtttgc attttctgtc aatgttttct tacaaagaac gctgtgatat actgaaattt 3351241 gtccgtatac attttggagg aatggatatg ttaccaaaat acgcgcaagt aaaagaagaa 3351301 atcagttctt ggattaatca aggcaaaata ctgcccgatc aaaaaatccc taccgaaaac 3351361 gaattaatgc agcaattcgg cgtcagccgg cataccatcc gcaaagcgat cggagacctc 3351421 gtatcacaag gtctgctgta cagcgtgcaa ggcggaggca cctttgtcgc ttcacgctct 3351481 gctaagtcag cgctgcattc caataaaacg atcggtgttt tgacaactta catatcagac 3351541 tatattttcc cgagcatcat cagaggaatc gagtcctatt taagcgagca ggggtattct 3351601 atgcttttga caagcacaaa caacaacccg gacaatgaaa gaagaggctt agaaaacctg 3351661 ctgtcccagc atattgacgg actcatcgta gaaccgacaa aaagcgccct tcaaacccca 3351721 aacatcggct attatctgaa cttggagaaa aacggcattc cttttgcgat gattaacgcg 3351781 tcatatgccg agcttgccgc gccaagtttt accttggatg atgtgaaagg cgggatgatg 3351841 gcggcggagc atttgctttc tctcggccac acgcatatga tgggtatttt taaagctgat 3351901 gacacacaag gcgtgaaacg gatgaacgga tttatacagg cgcaccggga gcgtgagttg 3351961 tttccttctc cggatatgat cgtgacattt acaacggaag aaaaagaatc aaaacttctg 3352021 gagaaagtaa aagccacact ggagaaaaac agcaagcaca tgccgacagc cattctttgt 3352081 tataacgatg aaattgcgct gaaggtgatt gatatgctga gggagatgga tcttaaagtg 3352141 ccggaggata tgtctattgt cgggtacgat gattcacatt tcgcccaaat ctcagaagtg 3352201 aaactaacct ctgtcaaaca tccgaaatca gtgcttggaa aagcagccgc caaatatgtc 3352261 attgactgct tagagcataa aaagccgaag caagaggatg tcatatttga gcctgagttg 3352321 atcattcgcc agtccgcacg aaaactgaat gaataaaaaa agcaatgtat gggtctcccc 3352381 gctacattgc tttttttata gctgttatct gtttttccaa acgtcagcga tgatttcaaa 3352441 cgaacgcatt ctgtctgcgt gttcaaaggt ttctgagtta accataattt cgtcagcctg 3352501 tgtcgttttg acgaaatctt caagcttcgc cttcacttct tccggacctc cgacaatcgt 3352561 ggagctcagc tgctcattga ccatcgcttt ttcatacggg ctccagattt ggtccatatc 3352621 ctcaacaggc ggtttaagct ggttaggcgt accgcggaca agatcaagaa acctttgata 3352681 atgggaagtc gcaaggtgct gcgctttctc gtttgtatct gccgcgataa tggtgacacc 3352741 gaccatcgca tacggttcgt cgagcacgtc tgacggcgtg aaggaattgc ggtacagctc 3352801 caaagcggga accgtattcg ccggtgagaa atgggccgcg aacgcaaacg gaagaccaag 3352861 ttcgccagcc agacgggcgc tgaagccgct tgagcccagc agccaaatcg gcacatctat 3352921 gccctctccg ggaatggcgc gaacttgatt gcgcacattt cctgacggtt taaaataatt 3352981 gcgcagttcc tctaattgtt ctggaaaatc ctccccgctg ttgatgtttc tgcggagcgc 3353041 tctggctgtc aattggtctg ttcccggcgc acgtccaagc cccagatcaa tccgcccggg 3353101 atacagtgtt tccagtgtgc cgaattgttc agcaatgact aatgaagagt ggttggggag 3353161 cataatgccg ccggaaccga cgcggatttt cttcgtgcct ccggcaatat ggccaatcaa 3353221 aactgcggtg gcagagcttg caacaccttc tatattatga tgttcagcaa gccagtaacg 3353281 gtgatagccc cattcctctg cccggcgcgc caagtccatg ctgtttcgga atgattctgc 3353341 aatcgttcct ccctgaacaa ccggagataa attcaagaca gaaagcaagg tatctttgcg 3353401 ttggttgtta gacatattgt tctcctttgc aaatgtgtta tcagtaaaca gcccaaagct 3353461 gtcaggtcat gattgaaaga acttctatca caccataaca caactgcatt caggaataaa 3353521 agaatttgat tcgatgaaat tcgaacaata taaaacgaac ggtttggaac attattctgc 3353581 tccaaacaac tccttagcca tctcaataaa gagcttagcc gccagagaag cctcctttag 3353641 cgacggaaca gcaagctgca catcacggta tacctgcggg tccaattccc tggtcaccac 3353701 atgctctggc agcggcatcc ccgacatgga catttctgat aaaatggcca ggcccaggcc 3353761 ttctctgatc atactgatcg aggtgttgat gttatagacc gtgaaagctg ggtgcagcgt 3353821 agcacccgcc tgcctgaaca tatcgataaa tggtgattca tagccgccgt cacagacgat 3353881 catcggttca tggtcaagat ctttcagcgt aatggctgaa tgactggcaa gcgggtgatc 3353941 gtccctgagc acgacagcca ttttgtcttt tttcaaatga atgtactcca tctcctctgt 3354001 tggatacaga agaatcccaa catctatcat ccgcgtatga agccactcct tgacttcatt 3354061 tacagttccc tcgtgcagca cgagctcaag tttcggatat ttttgtttaa attcactgat 3354121 cagcttcggc ataaaataag ccgaggcagt tgagaatgtg ccgatatgga tcgttcccag 3354181 ttcaagccct ttttccgctg ctgctacctg ctcaactttt tcaatgcctt ttaagacttc 3354241 tctgatgtgt actaagatct gttttcccgt atccgtcagc atcaggccat tgcggcggtc 3354301 acgaatgatc agctttacat caagctcagc ttcgatcgca gaaatcgcat ggctgacagc 3354361 cggctgtgtc atgttcagcg cctgacccgc ttttgtaaag cttcccgttt cagctatttt 3354421 cacaaaaacc tttaattgag taatggtcat aacaatttac ttatgctcct tataaaaaag 3354481 attcatttta tttatcttat gttctaccgt atcatatgat ggaaaagttc tacaaggagt 3354541 gaatgaacaa tgaagcagct cccaaaaacg cggacagctc tcctgctcgc atttctcgtc 3354601 atcatgtggg gcgtcaattg gccgctgtcc aaagccgcgc tcgcctattc tccgccatta 3354661 ttgttcgcgg gcatccgaac gctgatcggc gggcttttat tagtcatagt cgcactgccg 3354721 cgtattcata aattacgctt aaaagaaacg tggccgattt atcttgtttc tgctctttta 3354781 aatattacat tattctacgg cctgcaaacg atcgggctga attatcttcc ggccggcctg 3354841 ttttctgcaa tcgtcttctt ccagcctgtt ctgatgggtg tattttcttg gctgtggctc 3354901 ggcgaatcca tgtttgtaat gaaagtgatt ggcctcatcc tcggttttgc gggagtagcc 3354961 gtcattagtg ctgcgggctt tggcgggcat atttctgtca ttggggttct gctggctctc 3355021 ggctccgcag tcagctgggc gctcgggaca gtatatatga aaaaaacagg cagccgcgtc 3355081 gattccatct ggatggtcgc tctgcagctg acgatcggaa gcgtgtttct gcttatctcc 3355141 ggcttttgga cagaaagctt ttcggcgatc caatggacag ctccgtttat tacgagcctg 3355201 ctgttcatct ccgtattcgt tatcgcactc ggctggcttg tcttttttac gcttgtcggt 3355261 tcaggagaag caagcaaggt cgcatcttat acttttttga ttccgctcat atcaatcgtg 3355321 gccagctcca ttttcctgca tgaaccgctc acccttagcc tcttggcagg gctgctgctg 3355381 attgtcacga gcatctgtct cgtgaataca aaatcaaaag cgcagaaagc tgcggcgatt 3355441 ggtataaacg agaaagctgc acaataataa aaaccctctt gccggatgcg gcaagagggt 3355501 ttcttattta ctgatgcttg cgtcctttga ccaaatatgc aactgtaatc aaaaggtaga 3355561 tcgccgcagt aatgccggta atgacaattg atgttgtcat gatgaccccg atcagaatgg 3355621 cgagtaatgc cacaatcgca aaccatgtcg tgtacgggaa ccattttaca taataggccg 3355681 gtgtttccgt ttgctgtttt ctcgatttta aatgagcgaa tccgatgatc agccaaatga 3355741 ataaaacggt atatcccaat gatcccatta aataattaaa tgtttggctt cctgcgaaca 3355801 gagaaatcaa tacgccaata tagagagaag aagtgcacat cagaatcgca aacatcggta 3355861 cgtttttcga tgaaagcttc gagaagacct ttggaagcct tccgtcactt gcctgtgtat 3355921 acaaaatgcg tgatgatccg tataaacctg aattcataga agaaatgatc gccagcagga 3355981 tgactgcatt catgatatga tccgcgcccg gaatgcctac cattttaaag accatcacga 3356041 aaggactttc cggaacggaa ttgacttggt tccatggaat caggctgacg atgatgaaaa 3356101 acggcagcag gtaaaacgcg acaatccgtg tcagtgtgct gcggacagct ttcgggacaa 3356161 ccttttccgg attttttgtc tctgcaagcg ttacaccgat aatttctgta ccgccgtaag 3356221 agtagatgac gacaagcatc gccgtgatca gccctgtgcc gccgtgcggg aaaaatccgc 3356281 cgtggtctgt caggttggaa aatccggatg ctgtatgatc accgaatgat acaaataaga 3356341 gcagcaatcc cagaataata aagataataa taacggtaat cttgatcatt gccagccaat 3356401 attcagtttc ggcgaagatt ttaacagaaa gcaagtttac aatcgtgacg ataagagaaa 3356461 ttcctaatgc caacacccag atcgggcagc ccggcagcca atattgaatg aaaatcgcag 3356521 ctacaacagc ttcagccgca atgttaagca cccacatttt ccagtagatc cagtccaaaa 3356581 agtaagcagc gtaatttccc aatacctgct ggacaagatc acggaaggtt ctggcgttac 3356641 ggtttcgaac agccatttcc gccagcccct gcataataaa cagcaaaata atcccgccga 3356701 gcaggtatgc gataatgaca gatggccctg ccacatcgat cgctgagctg ctccccttaa 3356761 ataaacctgc gccgattgct ccgcccagcg ccatcatcat aatatggcgg gacgtcatcg 3356821 tgcgttttaa cgtttgattg tcgtttttca tcctcttcta cctctccttc tcgttttcaa 3356881 aaacaaaaaa gcccgccgtc tcctacctaa tctaatagat aaagagacga cgagccttcg 3356941 gctgaccgcg gtaccactct tgttgattct tcatgaagaa tcctgctttt gacctgtaac 3357001 gaaggttagc cgttaaaaca tagggaatat tcaatctatt ccgttccgtc ttaccactcc 3357061 cgggcgagtt caaagaagaa tcaggctgcg tcgcaccacc ccgcagctct ctgttctgat 3357121 cactttcttt tactgctccc aatctatgtg ttttagtttt ctgaaaaact caaattttat 3357181 gatctgaata tattaacata atatacgtgc ttctctttta actgtcaata acttcagaga 3357241 aaaaagaaac tgttattttg tcccttttcg aatggctttc caaaaggatt ctgactcgtt 3357301 tcctaatgcg taaactgaaa cacctgctat tttatattgc tttgccagat ggcttttcgt 3357361 ttgaacggtt ttttcgtttt cataccacac gacatgttta tgcttctttt tgtcaacata 3357421 agaaaacgtc atcgagcctg attttttgtt gaatgccggc tttgcttttt gttttttgat 3357481 gagggatttg agctcattcc attcccttat tgtgctggta cttccgtctt ttacatccca 3357541 gtcatagccg tacgcaggga ttcccatgat gactttattg gctttgatct ttttgactga 3357601 aaactgcaga gagcttttga tccagtttgt gcttgccact gaccccggct caccccaaat 3357661 gccgtgttca tcgtaggtca tgacttgtac gaagtcggca tatttgccga ttttcgcata 3357721 atcatacggc cagctccagt catcattttt atcatcggcg cttttggccg gaacggatac 3357781 cattgtttta atatgtttct tattcaaagc ctgtgagaca tattgaatga agttcgagta 3357841 tgcagcgcgg tcttctggat ttactgcttc aaaatcgata ttgattccgt aatatgagtg 3357901 ctttttggcc agtgtaatta actgatctgt gaatcgtttt ttcgctgttt tattgctcat 3357961 gacccgactc gctaaatctc cgtcaaaatc ataaatggca tcattatagt ttgaaatgac 3358021 agcccatgtc ttgatttttt tctttttcgc atatgtcagc tgcttagttg gggcatcgcc 3358081 aatgatttgt ccgttttttt caaacgcaaa tgtatcggtt gcgatggcat tcatgtatgt 3358141 atgatatttc gtaagagaat tgtatgaagc cgtatcccca gtcgtgtagc ctactgtcat 3358201 accggctgcc ttcgcttctc cttttgtata cataaacaga acaatcgcaa tcgccagtga 3358261 aaccgctatg atcagccatt ttttcatcgc atttcctcct gtatcaagtc atactcttct 3358321 catcggccaa aaaattggaa gttgaagttt tttcaagcaa aaagcccggc atatgcctgc 3358381 cgggcttcct gagttcagcg gtcagagacg agaatatatg ctgcctttac tggtccatgc 3358441 acccccacaa ctaaatccat ttcaatgtcg gctgagttac tcggtccggt aatgtagttg 3358501 atacatgaag gaacagtgac accgttcgca atgttttggc ggatgatatc actggcttgt 3358561 gtcattctcg gtacaatgct tgatttcggc acgatcgcaa tataagtcgt tggcaaaagg 3358621 ctgacagagc ggccgatgtc ttttgaggag aagaggacaa ccgtccccga ctcagccaat 3358681 gtaatttcgc tgaatgtaat ccctacattg gcttgctccg cttttttaat attttcctcg 3358741 cctttgtcag catcccactc ccagaccggc gttccttcac tcggccagtc cttggtgagc 3358801 aggcttttca gtccgtattc ttcaaagcgg gggtccttcg gaatgatgac agggcctcca 3358861 gaaaagcggc tgacttgctc gcgcagggca tcgtaaaggc cggttgaatc cgtttcaatc 3358921 agctctgtat ggattttgac acaatggttt ttgagcactg tgactaagtc atccgctgaa 3358981 taaccttcaa gtgttttata ttgcggctga tgcgcccatt cagggactgc cacgcctcct 3359041 gttcttcgtt cacggcccag gctggatgcg attcggttta aaaagctctc ttgattctga 3359101 atggttccct tcgtcatcac tgctcctcct tcgtgcgttc acttgtttct ctgtccgcaa 3359161 accagtctct gaatctcgat ttatgcggtg ccgggaagtc gcgaatctgg gtccaatttt 3359221 taagcgggcc gggccctttc gaaatttttt cgtcctctgt aaaaggcgtc atggcggccg 3359281 gcgcccattt tgagcccatt ttgtaaagcg ataaggagga tgcgccaagt ccgaatgctt 3359341 tcattgcaag cttttcactg atcggcgccc tgccttcttt ttcgacgata ttctgacgat 3359401 gcttgagtag cagctcatga agcgggattt tgaccgggca ggcttctgaa caagcagcgc 3359461 acagtgaaga tgcgtacggc agctccttat aatcgtcata accgccgagc aacggtgata 3359521 aaacagctcc gatcggcccc gagtagattg agccgtatga atgtccgccg acatggcggt 3359581 acacaggaca gacattgata caggcggcac agcggataca ttgcagcaca gactggaatt 3359641 ccgttccaag gatattggat cgtccattat caacgatgac aagatggaat tcttccggac 3359701 cgtccacttc accttccagc ttcggacccg tcaaagctgt aatatagctt gtcagccgct 3359761 gtccgacagc acttctagtc agcatgctga ctagcacttc aaattcagaa aatgacggga 3359821 caatccgctc cattcccatg acggtaattt gtgttttcgg caaggtgctc acaagccgtc 3359881 catttccttc attggtcaca aggctgacgg aacccgtgtc agcgatggcg aagttacagc 3359941 cggtaatgcc gatatccgct tccagaaact ttttccggag aatggcgcgc gcatgcatca 3360001 ccagctcttc cggtttttct gtatgttgat agtccagtct ttctttaaac acatcgcgta 3360061 tctgctcttt atttttatga agagcgggcg ctacgatatg tgacggcgga tcgtgatcat 3360121 caatctgcaa aatatactcg ccgagatcgg tttctacgac ttcacagcct tccttctcca 3360181 gcacctcatt cagattgatt tcctctgtga ccattgattt agatttcaca attttcttcc 3360241 cgttcttctt ttgaatgaca tcccgaatat aggaagacgc ctcttccgct gttttcgcga 3360301 aatagacatg tccgcctctt ttcgccacat tttcggcaag ctgtccgaga tagaaatcaa 3360361 ggttttcaag gacatgctgc ctgatttcct ctgataatga gcgccactcc tcccagtttc 3360421 ccagttcttc tgctgcctct aggcgccgcg tccgcagacg ctcctgtgca cctgaaacag 3360481 cgcctctcat aaattcatta tcaatcccct gtgatacccg ctctttaaaa gcgtcagtac 3360541 cgattttcat cgccatgatc ctttccccct ctgaatccag ttttatctgc tgttgagcac 3360601 ttcggcgatg tgcatcactt tgacattctt atcttttcgg ccaagccgtc ccccgatatt 3360661 catcaaacag ccgcagtcag caccgatcag cacctctgct cccgtttcct ccacacattc 3360721 gactttttca tcgaccatct gctcagaaat ctgcgccatc ttgactgaga acgttcctcc 3360781 gaatccgcag cagttatgtt tgcccggaag ctctgtaaac tgcaggccct tcacatggct 3360841 caacagcttc atcggctcct tccgaacacc cagcagccta gtcatatggc acgacgtatg 3360901 taaggtcgct tttgtatgaa gggtcgcgcc gacatcctct accccaagga cgttcacaat 3360961 aaaatctgtc agttcatacg ttttatccgc cagctttttc gctttatcgg cccatttcgg 3361021 atcatcctga aacaggtgcg gatactcccg gaacatcgtt gtgcaggaac ccgaaggact 3361081 gacaacatat tcggaatcct gaaacgtttc gatcatccgt ttcattgctt ttttggcgtc 3361141 atgtacatag ccgctgttgt aagccggctg tccgcagcaa atctgccctt ctggaaaatc 3361201 aacctcgcac ccaagccgct ccagcagctc aaccgttgct tttccgacat ttgtttgaaa 3361261 catatcaaca agacaagtga caaaaagtga gactttcatg atgaacccct ctctcatccc 3361321 caatatatga tcaggtcatc tgatgacctg agttaaaata actatatgaa tatcgtacac 3361381 tattctgaca atggaaggaa agagttttct agggatattt tcatttgtgg catatcaaaa 3361441 acactcccga tctcccagga gtgcagtata tggttagatc cagccctttt cctcagcgat 3361501 gctggcggct tctgtccgat ttttcgcatt aagcttttgg atgatttctg agatatagtt 3361561 tcgaactgtg ccttgagata aatagagctc cagcgtaatg tcttttgttg tcttgcctaa 3361621 agccgcaagc ctcagaattt cttgctctct aacggttagc ggattttcgt ctcgcatcat 3361681 attaaacgtc agctcagggc tgaagacacg ttttcccttt acacattttc gaatggcatc 3361741 ggccagatcg tcaatttcac cgtctttcag cagatagcca tgtgcaccgg cctttacggc 3361801 gcgttcaaaa tatccggggc gggcaaaggt ggttaaaata atgaccttgc tgacgcagcc 3361861 ttttttcatt aattcctctg ccacattcag cccgcttcga accggcattt caatgtccat 3361921 aatgcataca tccggctcca gcttcaaaat agcatgtagc gcctcttccc cgtttaatgc 3361981 ttgtccgatg actgtcatat cctcttctaa atcaagcaaa gatcccaaag cgcctaaaag 3362041 cattcgctgg tcctcagcaa taaacagacg aatcattctt ttcgtcctcc aatcattctg 3362101 cttttttaat aagcggaatc gtcagtgcca caaccgttcc gttatggtct gaaaccgtta 3362161 atcccccttc aatgagcatg agccgttctt ccattcccca caggccattc ccaaacattt 3362221 tctccttcgg cgctcccttt ccgtcatccc gtattacgat cctcattttg tcagcaaatt 3362281 gagaaatggt gatggcacag tgggttgctt tgctgtgctt gataatgtta gtcacggctt 3362341 cccgcataca catactgata atattttgag tgacgggaga tatcactgaa aagtcgtcgg 3362401 ctccttcgta ttgaaaggta atgttccccg ctcttaatat gtgctgaatg tttacgagct 3362461 cctctgttat cgtgaccgtt ctcatatcag aaaccagctc tcgaacttgc ttgagtgcgg 3362521 agcgtgaact ggtttccatt tcttttgcct caagcttggt ccgttctgga tcagatgcag 3362581 ccagccgctg aatgagctgg ctttttaatg taagcagcga cagggtgtgg ccaagagtat 3362641 cgtgaagatc acgggcgatt cgaacacgtt cctccctttt agagagttct tttatctgtt 3362701 cgttggcttg tgcaagctta gcttcaagct caatcctccg aaacatagaa cgaattccga 3362761 atggagaaat gagcataatg acgagaaacg ggagaacaga aaaaagctcc cgaagcgaga 3362821 ccgaattcgc gataaattgg tataggcatg gaaaaagcag tataaagatt aaagcgcaga 3362881 acgcacggtt aaaattcgtt ttctctttgt aataaccaac aaagtttgcc ggaaaaaaac 3362941 ctaagtatat ataggtgata ttgtaaaaca cactatacat caaaataacc gccatttgca 3363001 cgataagcca atatgtaaac gaagctttgc ccacgctgca gaataactgg cgatatgccg 3363061 ctacaaaaag gagcagcata ccatatccga tcccctgttt gacccctgat tcttttaata 3363121 aagagaggaa cggcataatc gtatacacca gaaagatata agggaaaaac ccgaattcct 3363181 tcgggaaaat agatattgcc tttttcatgt attacaccgc ttcttgtttt cttcttatat 3363241 atttagatag tagcatgaag agcatcatat aagcgattaa tatcagaata tttttccaag 3363301 tcggactccc accccggaca agttcccacg ctccgctccc gaaatgataa gacggaagcc 3363361 actggccaat gctctgcatc atgtcaggca tgacctcaaa cggcatccac atccctccgc 3363421 ctaaagccag cagcatataa agcacattac tgattccggc cgctgtttct acttttctca 3363481 tgaggccgat tagtgtgcct aatgctaaaa aaggcaatgc gccaaacaaa atccacagtc 3363541 cgctcatcat ccattcaaac ggtgacaagg caatatcatt gatgattgcg ccgaacagaa 3363601 atatgacggt aattgataaa acgtgaatga cactttggcc gatcatctga gctgataaat 3363661 agatatgatc cggaagaggc gtaaggcgga taaaggcggc ccagccttgt gaccgttctt 3363721 gtaccattcg gatgccaagc gtcatgatag aggaacccat cacgctgaag actgtcatcg 3363781 acatcaggta atgggcttcc catgcacgtt gatcagggac gttggtattc actacatttg 3363841 taaagaaata ataaaaggca atcggcatga tcagagacca aagcacaaag tacttgttcc 3363901 taagcaccct tttcatttca gcgatgcttt gcttttgcag cacgttcact cacatcgcct 3363961 ccctgttgcc gtcagccagc tggcgaaatg cctcatcgag cgttgcttgc tcaattcgaa 3364021 tatcccgtgc atgtatgttt tcttgaaaga tcagcgccaa cactttgtct gtatttgatg 3364081 tctggatgat ggttctctca tgctcgtgga tcactctctc gacttccggg tgacaagaca 3364141 gcctttccaa tgattcactt gaatgaagcg taaaggaaac agactgtttt tgaattcttg 3364201 agcggatttg cattggtgag ccgtctgcaa caagctgtcc ttcagtaaaa aataggattc 3364261 gctgtgcggc atcatctgct tcctgtaaat aatgagttga aaaaataatc gtttttcctt 3364321 ggtccgacag tccgtgaatg gtctgccaga atcggtgtct tgatgaagtg tccatgccga 3364381 ctgtcggttc atcaagtata agcagctccg ggttcccggc aagagccaaa gcaaagctca 3364441 aacggcgttt ttgtccgccg gataattttt ctgctcttgt tttcaaatct tctttggtga 3364501 gtgctgttaa cgaaacgagt tctttcatgg acaatggatt cggataatag ctccggaaga 3364561 gttcaaggat ttcatccacc ttaaggcccg gcatgacact tacttcctga agcattacac 3364621 ctattttttc acgaacctgt tgatcatcgg gaacccggtt aaatagtttg atttctccct 3364681 cactcggttt cagcaatcct aatatcatcg agacgacggt cgtcttccct gccccatttg 3364741 gcccgagaat ggctgcaatt tctccttttt caatactgaa gctgatgttg tttacagcgg 3364801 tttttcgctg gaaatgtttt gtcacgttgc ttactgttac tgcttctttc atcacatgag 3364861 cacctcctga tcgtttacat tgattgtaaa atgacggaga agacgatgtt agtatggggt 3364921 gtcatgatga tggagtgaca aatgtcattt ttttctcacc ccggtgtcta ggcaatcctc 3364981 ctcctgcatc ttccaattca tccatctttt ctatctccca tgtcctcttt cttttaaact 3365041 gctgtgacat tcatagaaag atacactctt caaaccatcc gagtgttatg atagaaatat 3365101 tgaactttat attactttcc ggctgaaagg agccaatcat gaacgaagcg attttgtcta 3365161 gaaatcatgt gaaggtgaaa ggcagcggca aagcatctat catgttcgca cctggttttg 3365221 gatgcgatca aagcgtgtgg aatgccgtgg cacctgcctt tgaagaagat catcgggtga 3365281 ttttatttga ttacgtcggt tcgggacatt cagatttgcg cgcatatgac ctgaatcgtt 3365341 accagacact tgacggctat gcccaggatg ttcttgatgt ttgtgaagct ttagatctga 3365401 aggaaaccgt gtttgtgggt cactccgtcg gggccttgat tgggatgctt gcatccatcc 3365461 gccgcccgga gcttttttcc catctggtga tggtggggcc ttctccttgc tatttgaatg 3365521 atccgcctga gtattacgga ggatttgaag aggagcagct ccttggcttg ctggagatga 3365581 tggagaaaaa ttatatcggc tgggcgactg tatttgcggc aaccgttctg aatcagccag 3365641 atcggcctga aattaaggaa gagcttgaaa gccgtttttg ttctactgat cctgtcattg 3365701 cccgccaatt cgcgaaagcg gcgttttttt ctgatcaccg agaggatctt tcgaaggtaa 3365761 cggttccctc tcttattctc caatgtgcag atgatatcat cgcacctgca acagtaggta 3365821 agtatatgca tcagcatctg ccttatagca gtctgaaaca aatggaggct cgcggacatt 3365881 gccctcatat gagccatcca gatgagacga tacagctgat cggcgattat ttaaaagcac 3365941 acgtgtgata taggaacgaa agggatagag gtgaccctct tagatggaca aacaattgaa 3366001 tgatgcacca tgcggtttcc tcgctttgtc agaagagggg tcgatcatag ctgccaaccg 3366061 cacccttatc aagattctgg attatgaacc ggagcaggtt atcggccagc acatgaatat 3366121 gatgttgacc attcccgcgc agcttttctg ccagctttat ttttttccgc ttttgaaatt 3366181 ggagcatcac atcgaagaaa tatacatttc cctgaaagca agagatggag aagaaattcc 3366241 cgtccttatc aatgctattg cgagacacga tagcggggct tctgtctttg attgtgttct 3366301 gattccaatg cgaaagcgaa atgaatatga aaatgagctg ctgatagcca gaaatgaggc 3366361 tcaggaagct ttgcttgcca aacagaaagc caatgcggag ttagaaattg ccttggaaac 3366421 gctgaaagca aaacaagaag aacttcttga gatcaataaa caaaatcaac aatttaaatt 3366481 aaacaccaaa agagagcttg aactcgccag aaagatccag aaaaactcgt tgactgaacc 3366541 gattgtaaac gatcaggttc agattgactc ttattacaac gcatcgagtg aattgtcagg 3366601 tgatctttac ggatattatc aaatcgatga acaccgttac ggcattatta tccttgatgt 3366661 gatggggcac ggaatttcat ctgcattgat tacgatgtct cttcatcctt tgttccagcg 3366721 ccagatcacg caaggtctca gccccgttaa agttatgaag gaattggacc ggcaccttca 3366781 cagcttgttt caaaatgatg aggaagcaag acattattgc actgctattt atctcgagat 3366841 tgatatagca cggcaaagaa ttgattatgt caacgcaggg catccgccgg cactttggca 3366901 ggacgatagc ggaactcaac atctgcttca cgcgacctcg cctccgatcg ggatgtttga 3366961 agacttagag tttcagtcaa gcagcctttc atacacggag gacggaagat tgcttctgta 3367021 tacggatggc gtgatggatc ctacggcttc atgttattta tttgatttac taaaggatca 3367081 tcctgattcg ccaatcgctg acctgaagga gaaaatcctt acatcactgc agcatcaaaa 3367141 ggaagctcat cataagagtg atgacgaatg ttttatatta gttgatgtaa aataaaatga 3367201 tccatgagac ataacaatga tttgttacat ctcatggatt tttttgtttc agcgtttctt 3367261 tggaatatgt cctgactccg catattgaaa cacctgcaag gaaggcagcg ggtgtccatt 3367321 aaaatcaaat aaagcttgat tatctacagc acttccccca taccacttcc cggcgtcttc 3367381 agggtcgtat tcagcagcat agctggacgc ccaccctgac ccgtatgttt cccataacac 3367441 tttgtttttc tctatctgtg tcttcggccc gactggaatc cacgccggct cccagtagaa 3367501 aacaccaagt cctgctttgc ccgtattcgc cactgcctcc attacatctc ttactgcagt 3367561 tgcctggcct tgaacagaaa ttggatatgg caacgtctgc ccgctttttg gtgctgtatt 3367621 tccatgccca tcgccatcct cagcggtata ggtgtacgat gtctccgcca ccatgacttt 3367681 tttgccgtac gtattggcaa cagccttcag cacggaggtc aaattttgta atgtgccatg 3367741 ccagaaagga taataggagc tagcaaacac atcataatcc actttgtttt tgctgagtgt 3367801 ttctgcaata aatgaatacc ttccagccgt ttcaggattg gtaaaatgca gggcgaccaa 3367861 aatatttgaa tttgtctccc tgaccgctcg gcttccttca ttaaataatt ggcacatctt 3367921 cgtccaatca gtctcaccgg caaatcctcc tgttgtttca tttccgacct gaaccatgcc 3367981 gatgtcaacg ccttccttga tcatcttttg caggctttgt ttcgtatact catagagctt 3368041 tgcttttttt gcttcaaagc tgagattcgc ccaggctttg ggcacctttt gtttcgctgg 3368101 atcggcccag aaatcagagt agtgaaagtc ggccagcacc ttcattccgt tcgctgtcgc 3368161 tctttttccg atttcgatgg ctttttgaac atcattgttt cccccgccat acccgttgcc 3368221 atttgaatca tacgggtgat tccagatgcg gacgcgaaca tagttgaccc cagcctgttt 3368281 taaagttgta aagatatcct ggcgttttcc gtttgtattg taaaaggtga caccgctgtt 3368341 ttccaaagca ataacgctgg atacatctgc ccctttgata aaatccttgt tcatcccctc 3368401 tactttttta acaaaaagat cctctgcccg aagctctgac acgtgcttct ccttctcaat 3368461 ggcagcggca tatcctgttg aactacatgc actccacacg atggcagccg caaagaacat 3368521 tttcactttg cttttcatga tttcatcccc ccaagactta gcaagcgttt tcattctata 3368581 gaaaaaagaa tccgcccata tcgagcggag catcagccta atgtgtgttt acgacaattc 3368641 tcacttcata cttttccatc gtcaggtcgc ctgacaatat gtctcctgtc attatgtcct 3368701 tcacactctg atcaaacgtg accagctgtt tttcttccgt gaaattcatg acaaaaatat 3368761 aatcattgtc ctgatcctgc ctcgcttgta cggagacgcc ttttccgtgc cgaaccggaa 3368821 aaactggaga gagagacagg tctgtgatca gaccctcata gaaatcacgc tgaaattgat 3368881 cctccaaacg cgcgccgata aaatacgcct tgccctgctg atactcatgg cttgtgaccg 3368941 ctggcgtgcg cgcataaaaa tcttcttgat acaccgcttc cactgaagct gtctttacat 3369001 caatcacggt tgcataatcc ttcatttcat atatttggct gcggtagctg acagcgtttc 3369061 gatccttcgg atacagggtg tccgtttcaa gaggctcaac tccaaatata gcttgaagat 3369121 ccggatgcca tccgcctgtg tatgttaagt catgctcatt cacaaccccg ctgatatacg 3369181 tcatgactaa ggtgccgccg tcagccgtaa acgcttttaa acgggaaacg gtgtcctcgc 3369241 tgattaaata cagcatcggg acgatcagca gtttatatgg tgaaaagtct tgttctttcg 3369301 tgatgacgtc gacagggata tcgtgttccc agaatgtgcg gtaatgctgc tgaagcgttt 3369361 gcggataacg ttttgtcgcc ttcgcaaacc cctgagcatc ctcgagcgcc caatgatttt 3369421 cccagtcata taaaatcgcg gtttgagccg gcctcttcgt tccgacaact tcggacagcc 3369481 gttccaatgt ctcgcctacc ttggccactt cttgaaagac gcggttcttc gggctattgt 3369541 catgatccac aaccgctccg tgtaattttt ctgatgaccc ccgtgatttg cggtattgga 3369601 aatagagaac gctgtccgag ccgtgggcaa tcatttgcat ggatgacagc agattcatgc 3369661 ccgggcgctt tgccttgttg acgttatgcc aattgaccgc gcttggcgta cactccatta 3369721 ataagaaggg ctgctgcttc aagcttcggt acagatcatt gataaagccg accttcatcg 3369781 ccaaatcagc tgtgctttcc cagtcattgt gccagacagg ataagcgtcc cagctgatgg 3369841 catcgacatg ctttgcaaat ttgctgtagt cgaggccctg atacgggatc aaatccggtg 3369901 tgtcagccat aaaattcgtt gtgataggga tatcaggcgt caattctttc agcggaatga 3369961 tttcattttc ataaaacgaa atcgtttgat cggtgacgaa ccggcgccaa tctaaattca 3370021 ggccatgcaa gccattttca ccgatcggcg aagggctttc aatttgtgac cagtcattga 3370081 acgtatggct ccaaaaaggg gtccaccacg catggttcaa tgtcttgagg ctgttgtcat 3370141 atttcgattt cagccactcc cggaaagcat gctggcataa atcacagtgg caatctcccc 3370201 cgtattcgtt tgaaatgtgc cacattaaca gcgccgggtg atgtccgtat cgttctgcta 3370261 ataagcggtt gatgtgccgt gttttttctc ggtagacttt agatgtgagg cagtggttgt 3370321 gccttccgcc gtgcagctgt ttgacgcggg aggcattgac gcgcaaaact tccggatagg 3370381 tttgcgacag ccaggccgga cgggctccgc tcggcgttgc taatatgacc cggccgccta 3370441 tactgtgaat ccgctcaaaa atatcatcca gccattcaaa ttgatatacg ccctcctccg 3370501 gctcaagtgc gctccatgca aaaatgccga cagaaaacgt attcgtatga gaaagcttca 3370561 tcagtttgat atcgtcagct aaaatatcgg gccgatccag ccactgatcg gggttgtagt 3370621 ctcccccatg gagcataaat tttgcttttg ttacgtgcgt tttttcaagc tttgacatca 3370681 cattctcctc cttgttctct tagcccttcg ttccgcctgc ggttaatccg gacacaaaat 3370741 tcttttgcag cataataaag atgacggcaa ccggtatgct gataagcagg gctccggccg 3370801 caaatgtcgt atagctggcc cccatgacat cattcactaa attgaataga ccgacgggca 3370861 atgtatatga ttcaggcgtt ctcaatatgg ttgaggacag cacaaaatct ccgagcggac 3370921 cggtaaagcc gttcatggcc acgactgccg ccatcggttt tgataatggc agaatgatct 3370981 ggaagaagat tctggtgctg ctggctccgt caatcttggc gctttcgtct aaatccatcg 3371041 gaatggaatc catgtaccct ttcatcaaat acgtattcat cgggatcagg ccgccgatat 3371101 aaagcaagat tagcagccag tggctattga tcattcccaa gatttgcgcc agcacaaaca 3371161 aggcaattaa agctgaaaac tgaggaatca tctgcagcaa taaaaagagc gttaaagcgt 3371221 atttcctccc tttaaaccga aagcgcgaaa acgcataggc cgtaaacgtc acacagagca 3371281 aagaccctgc cattgtaaac aggctgatct tcatagagtt gacataccac tgcacatatt 3371341 gaaggctttc cttgcccgca aataattcct tgtaatgatc gaatgtcgga tgcttcggaa 3371401 tgatggatgt actgattaag ctgttgccgg gattaaagct tgcgcctgcc gtccaaagga 3371461 gaggataaac aatgatgacc gccataaagg ctagcaacaa gtaagagaaa aggagacgga 3371521 tatatcttct gactttcata tctgccagca taccttatgc ctcctcttta aaagactttg 3371581 tctgtctgaa ctgccacaat gcgatggaga taacaaatac agataataaa atggttaaag 3371641 ccgcagcaag tgaatattgg ctggactgca ttgtcaattt ataaatccat gaaacgagga 3371701 tatctgtccc gccggctgtt gatccggtta cagccggacc tccgccattg aatagataga 3371761 taatattaaa gttattaaag ttaaacgtaa actgagtaat gataatcgga gccattgcaa 3371821 tgaacaccat cggaagcgtg atgtatctca gctttgaaaa gacagaagcg ccatcaatcg 3371881 tagctgcttc atacagatcg tccgggatgg attgcaatac gcctgttgag acgagaaaga 3371941 tgtacggaaa tccgagccag ccctgcatga gaatcaatgc aagcctcgac caattggcat 3372001 ctgtcatcca cggaagcgga tctatcccga agaaagccaa gatgtcgtga ttcatcgcac 3372061 cgaagctatc attaaacagt cccgcaaaaa ttaaaatcgt cacaaaaccg ggaacggccc 3372121 atggcaaaat cagaatcgtc cgaaaaaaac gtttaaaccg aaggtctttc tggttaacaa 3372181 tgatcgcgag aaaaatcccc aaggtgactt gcagtgtgga tgcagcaagt gtccaaacca 3372241 ccgtccaagc cagtacatca aaaaaagtcg acctccaaat atcaactgtg aaaatatttg 3372301 cgaacgtttg aaaaccgacc caatcaatta attttgcagg aggagaatga tacaaatcat 3372361 agtttgtaaa cgctaatgca aagctgaata agataggaaa gatcacggcg aaaattaaaa 3372421 taaacaaaga tgggccgctg acgacataag gatagccctc agaaatgata tgctggtatt 3372481 gttcctttaa ggaacttaat ggcttatttt catcacgctg ttttccgctt tggaacgcat 3372541 cgcgaagatt tacataatac accgcaaggc caaagcaggt cacgatgaca gcaataatcc 3372601 cttccgccag cagaaaaacg gaattatccc gcggcacttc tgttcccagt gtaaagattc 3372661 cccaaaaccc catattgagc agatctccaa agaccgcaaa aaacgatgcg cctaagaaaa 3372721 gaaagacaat accttttatc cattgcttgt tataaaattg cccgagtccc ggaatgatag 3372781 aaagcaacaa agcgacttga cgatgctgca ccgttttcac ctctcttaca atacaaatct 3372841 agctttctct ttattttccg ctgtgctttg ccttaatttg tcctttggcc gtttcagctg 3372901 cttgatccaa tgcttgtttc ggatctgcct tccctgttgc aaccgtctgt aatgctgaat 3372961 cagccggcgt ccatatttca ttcatttccg gaatatttgg tgttggctct gagaaacggg 3373021 attgttcagt aacagcccgt gccgcctcgc ttttcataat agccgggtca ttggctaggg 3373081 atttcacagc aggaacttct ttcgtttctt catatcgtgt tttagaattt ttttcatttg 3373141 ccaggaaaac ggctaattct tgcgccagct cttcattctt tgaaaatgca ctgacgttgt 3373201 agcttttgac gccgataaag gagctcatgt ttttcccatt ttccagcttc ggcagtttcg 3373261 taatgccata attgattcct gcattcgaaa aggcttctac attccatgga ccagaaataa 3373321 ttgcggcggc ttttccttct gtgaacagcg attccaacac gttaatccct tgttctccaa 3373381 taatgccagc cgggaacagg ccatctttgt aaaacttctg aatcagcgcc gcacctttga 3373441 cagctccttc attattgatt ccaatgtctg acgggttata gctcccatct ttggcctttc 3373501 caaaaatgta tccgccatat ccgctcatca cactttctgc ataataaatt tgatcgaata 3373561 gggctaaaaa gccaaatttg ctgccgtcag cagtcttttt ggaatagtcg taccactctt 3373621 ccagcgtttt gggcaattcc ttttctgtga tgagatcttt gttgtaaaaa agcacagtcg 3373681 tttcgaccgc ttttggcagt ccataaagct tttgatctac catttgagac tgaatggaag 3373741 cgtcagtata aagtgattga acgtcttttt tgacatgtaa ttccttgagt aatccttccg 3373801 tgacagcggt tccgatttgg tcccctggca ttgttaacac gtcagggcct gtgccggccg 3373861 gtccatccat tcgcaaatct tcaatctgct tggcatacgg tttttcaacg actttgacct 3373921 tcacatcatg ctctttttca aatgcagcca cagcgtcttt aatgccgttg ctcttttctt 3373981 tatcctccca tacaacaagc tctgaccctt ttgaactcga tttggcgctg ctgctttcct 3374041 ttgggccgca agccgccaag gataaactga cagctgcgca gagcatgaat acggaacact 3374101 tttttgccat tttcattgat tgtcaccctt tcggtaggaa tgaaagcgct ttaaagataa 3374161 tatagcatgc ctgagaaaat gtgtaaacaa actatttact tcatagagta aattttttta 3374221 cctaaataaa aaatgactta gtgtcctaag tcatccttaa ttcatactct tcctgacgat 3374281 taattctgcg cccacatata atgtttttac cgttcttctc ttgtcctgca cttgttcaag 3374341 cagtaattga acagcgtttt tacataattc atgtatatca atatgaaacg tcgtcagagg 3374401 aggcgagaca tacttcgcga agctgatgtt gttgatactc acaatgctta ccctgtttgg 3374461 tatggcaatt cctttttcgt tcagggcttg cagacagccc actgcaatcg ggtccgctgc 3374521 aatcataaaa gcagtcggaa gctgatcgcc taatgtgtcg atcgctgctg acatcaggcg 3374581 gtagccgttt tctacagaga atccgcgatg acagaaaata tagcgctcgt ccagcatggc 3374641 tttttccctc atataggatc tgaaggtttg ttcacggatg tccatttcat cctgattggt 3374701 attcggattt ttgtatgtgc cgccgataaa accgatgctc ttatgcccct tctcagtcag 3374761 gatgtttacc gtcttccttg tcatttgtgc caaatcgggc cttaccgagt caaaatgatc 3374821 gggatcagga gttgaatcga tgaacacgcc gttttcagtg agatttctga ggaaagccag 3374881 ctcttcatct gaaaatgtgc cgacggcaat aaacccttcc gtatgttcag gaatgctctc 3374941 gattccatcc gctattttat aagtggtcat atcgacattg aatgctttcg ccagtttctc 3375001 tacttctaat ctcatcgttt taaaatagac atcttctaat tcttctttat ctgtcagcca 3375061 atataaaaac gcaatatgtt tcaccagcgg ccttactgtt tttttgcggt aattgagctt 3375121 ttccgccgct tcatagattt tctcccgtgt ctcatcagga acagaaaggc tttcatcgtt 3375181 atttaaaacg cgggaaacgg ttgagattga aaatcccgct tcctgcgcga tatctttaat 3375241 tgtcgccatt gtatctgcct ccattattca gctcgcattg ttttagtaaa atattttact 3375301 ttctttttca caaatgtcaa gtgcacaaag ccctctggct gccatgtaaa aagactgaac 3375361 catttgcggc tcagtctcag ttgttcgtat cattcggaac cggcggaatt gcccgggaaa 3375421 tgagttggtt attgcacatt ttcctcgaaa tatcccgaaa gcacatcttc cacattcgtc 3375481 aaatgcgcca gcatggcggc ttccgcctgt gcaccgttcc cggcagccac agcattgtaa 3375541 atccgttcgt gctcctcata cagccgctga acggaggtct tcttggaaaa cagccagatt 3375601 ttcctcgttt ccctcattgt ttccagcagc aatgatgaca cgtgattcat caagtgttta 3375661 agaagttcat tttgagaagc gtccgcaagc gcaagatgaa atgcaaagtc tgctttctct 3375721 cccagctccc cgtccgcttc aatgctgccc atttccttta gtgcatcctg aattctttcg 3375781 agatctgctt ctgtcctttt ttcagccgct agtgaagcca cgccgatttc aagcagtttt 3375841 ctgacctcga gcagctgctt gacgtcctct tttttcatca gaagggcggc tgagagcggc 3375901 tgagaaattt gattgagctc aaattccttc agatacgtgc cttctccctg tttcatttcg 3375961 acaagcccca tcgcttttag cgcagaaagt gcttcgcgaa ccgctgaacg gctgacttga 3376021 aagctctcag caagcgcctg aacagagtcc agtttatccc ccggcttcaa ttcgccattt 3376081 ttgatcatat ctaatagggc atccgctact tcttcatata tttttttgtt ttaatctgtt 3376141 tatatttcaa tgcaattcac cccgtaactt gtaggtctgg ctgtttacga tctattatac 3376201 tctgttttgt gggccgccaa aagattttga ctattttgtc aaaaagtctt gtactttgat 3376261 ttttttcaaa atataatgct aggtaactgg tcttattacc cagtcatcag atgatcatat 3376321 catctataga aaccgcttac atatggcgcc agtttatgtt tcaaggaggg gtttgggatg 3376381 caatggacac aggcatatac gcctataggg ggaaatttgc tattatcagc gcttgccgca 3376441 cttgtaccga ttattttctt tttttgggca ctcgcgatta aacggatgaa ggggtataca 3376501 gcaggcttgg ccacattggg gatcgccctt atcattgctg tattggttta tcgtatgccg 3376561 gcggaaaaag cgctgatgtc cgcgacacaa ggagccgtat acggattgtt gccgatcggc 3376621 tggatcattg tgacgtctgt ttttttgtat aaaatcactg tgaaaacggg acagtttgat 3376681 atcattcgca gctctgttct ctcgattact gatgaccgac ggcttcaagc tctcttgatc 3376741 gctttttcat tcggggcttt tttagaaggg gcagcaggct tcggagcgcc ggtcgccatt 3376801 tctgccgcgc tgctggtcgg tctcggcttt aatcctcttt atgctgcggg gatctgtttg 3376861 atcgccaata cggcgccggt tgcctttggg gcaattggga ttccaattac agccgtagaa 3376921 gggccgacag ggattccggc gatggagatt tcgcaaatgg ttgggcggca gctgccgttt 3376981 ttatccgtat ttattcctct ttatttaatc atcatcatga gcgggttcag gaaagccttg 3377041 gagatctggc cggcgattct cgtatccggt gtttcctttg ctgttgttca atatctcagt 3377101 tccaattttt tagggcctga gctgcccgat gttttgtcag ctcttgtttc aatggctgcg 3377161 cttgctgtgt ttttgaaatg gtggaagccg aaaacaacat tccggtttgc cggtgaacaa 3377221 gagtcggccg cctcaattga aacggcgcgc acaaatccgg cggcgcctgc atacagaggc 3377281 ggacagattt ttaaggcttg gtcgccattt ctgctgctga cggcgatgat ttccgtatgg 3377341 ggcattccat ctgtcaaatc cgcgctgacc gggcattatg aaggctctgc ggtgttcttg 3377401 aagtggctga atgctgttgg agaaaaactg actttttccc ccggtgtgcc ttttttgaac 3377461 aatcagattg tcaatgctga cggtacgccg attgaagcgg tttacaagtt ggaggtgctt 3377521 ggttcggccg gcaccgcgat attgattgcc gcagtgctgt caaaattcat cacggcgatt 3377581 tcgtggaaag actggggaac cgtttttaaa gaaacagtcc aggaattgaa gcttccgatt 3377641 ttgaccattg cttctgtcgt tggttttgcc tatgtcacca actcctcggg aatgagcacg 3377701 acactcggga tgacactcgc gctgacaggt tcgatgttta ccttcttttc gcccgttctc 3377761 ggctggctcg gcgtcttcat taccggctcg gatacttctg ccaacctgct gttcggcaac 3377821 ctgcagaaag tcaccgcatt atcagtcggc atggaccccg ttctgtctgt ggccgccaac 3377881 tcttcaggcg gtgtcacagg aaaaatgatt tcaccgcagt cgatagcggt ggcgtgcgcc 3377941 gcggtaggac tcgccggaaa ggagtcagat cttttccgct ttaccattaa acacagtctg 3378001 tttttgctgc tgctcgtctg tatcatcacc tttttgcagc atcacgtatt cagctggatg 3378061 attccttaaa aaaatcctcc cgtctaggga ggattttatt tatatcgctt tctcgctgcc 3378121 gatgacggaa tattcatttg atcgcgatat tttgccacgg tgcgtctcga gatttggatg 3378181 ccgtgttgtt catacagcaa atcgacaagc ttttggtctg aaagcggttt tgttttgtcc 3378241 tcttgattga tcaggttttc cagatgcgtt ttgactgcat aattcgacgc atctccatca 3378301 cctgaagcct cggcttttgc tgagaaaaag agtttcatct caaacagccc gtaaggcgtt 3378361 tgtattgttt tccctttaat ggcccggctc acagttgatt catgaaggct tagacagtct 3378421 gccacctctc tgagagtcag cggcttcatt gcgcttcgcc ctttcagaaa gaaatccttt 3378481 tggcgtgtga tcagttcatt gataattctc gtgattgtct gttttcgctg ccgcagcgcg 3378541 cggctcagcc agcgccactc ctgatatttc gcagataaat aggagacagt atcctgacag 3378601 gagccggatg ataaaagcgt tctgtactgc ggatgcagat cgatctcggg aaacgagcgg 3378661 gtattcagtt ccgctgcgat gtgcccattt tttacggtga taaaaatgtc aggctcaata 3378721 tacacatctt gctctggccg ggcaaacaga aggccaggtc taggatgaag agccgcgata 3378781 tcatctgaga tatcttgaat ggtatgaagc ggaattcccg tctctactga aagcgttttc 3378841 catttttttt gcgcaaaagc atcaaaatga gctgaaacca gcatttccgc ttgttcattt 3378901 ctgttcggca gccgctgtaa ttgaagaagg atgcattcct gcaaagatct cgcgccgatt 3378961 ccagccggtt ctaacgactg gagttttgcc aaaacagcct ccgcttcctt ggccgataca 3379021 gataatcgcc gtgctgcctc ctctatatct tcttccaagt acccgtttga atcaagcgaa 3379081 tgaatcagat aattaaaaat ctttttttca gtgtttgtca gattcatatc gagtgactgc 3379141 tgttttaacg catcctgcaa tgttttttgc ggattactta attgaaggcc cgcttcctgt 3379201 gcattcatcc tgtttttgtt tgttttatgg taagatagtg gcggtgtgtc tgtttccttt 3379261 cgttcaataa gagggttttc cagtgagagc tcatcaatgt actcggcgag ttctgccgaa 3379321 tgatagccaa gcagcgtgat ggcctgcctg agctcctgtg tcagttgagg ctttaatact 3379381 tgtacttgct gaagtttcat atccatcttg ctcactcccc tttcttcatt gtacatgatt 3379441 gagatcacac cgtatacatt tatgaaaaag gagctgccaa agaaatgtct gaactttttt 3379501 ccgtccctta ttttattgag aatttaaaac agcatattga aatgaatcag tctgaggata 3379561 aaatccacgc gatgaacagc tactaccgtt ccgtcgtctc aacactagtg caggaccagc 3379621 tgacgaaaaa cgcagttgtc ctgaaacgga ttcagcattt agatgaagca tacaacaaag 3379681 tcaaacgtgg agaatcaaaa taaaccttcc gctcacatgt gagcaggaag gttttccttc 3379741 tttgaggcgt gctggatgag acgggtgctt ggcacgcctt ccatccaggt atgaaagtaa 3379801 ttggcgtttt tcccgtagga attatcaatg accgtgtttt ctttttgaag aagagaagac 3379861 aggatgtggc cgtgcagcct tgatgtttcc accgattcgt aacggctgaa aaaccgaatc 3379921 gctttttgga cgatataatc cgagtatttt tcccatatat acgcaatggg caaagggttg 3379981 cctgcttttt tattcaagac gttcagcgtt tggagaaaag caatcgtccg gcggtctgaa 3380041 gctgacagca ccgtgcgcca gtcgtagctt tccgcttctg cgtgttcctg aagcgcctgg 3380101 tttgcttcat gatctgttcg gataaatctc agcttttgat tggacggctg ctgcgtggga 3380161 atgacgggaa acagctgatg agccatatca ggcagaagct gaatgtgatt tgttgtaaaa 3380221 taggcctgtg ccgtagcata ggaggctttt tcccttgtca tgatgtgaag gttcgcatgc 3380281 ttagaaaata tctctgccgt ccgcttgagg ttgtctttgt tttgaaaata aatcgattgc 3380341 ggcaggatca caattttgtg gttcggatag gtttggacga ttttctctct aaagccttga 3380401 taatacggat acagatcccc gaagtttccg cctccctggc agacgatgat gagattcgga 3380461 tcaagctttc gcccgattgg gaaattgtct ggattccagc gttttctgac ccgaatcccg 3380521 tgttctttaa agaaggcttc tgttcctttc ataataaata aatcccctac attcccatat 3380581 agaggatagt cagcatatat aatctctgat tgtttcggaa tgacgtcgag cagcccggac 3380641 agtttctgtt tcaggctgat catcgaatgc ttgctgtcca tttcttcacc tcgacagtat 3380701 ggaataagtg cagtagcact tcaatgaccc ggccttgctc atcttctgtc atattggacc 3380761 ccgatgggag acagattcct cgcttgaaca aatcttcgca tacgcttcct gtatcttcat 3380821 gagaataaaa taaagccgga tcgaacagcg gctgggtatg gagcggcttc cacagcggac 3380881 gggcttcaat gttttcttca gcaagacgtt gaactatgtc atatgggctg agcccgttat 3380941 caagtgtgag cgtggtgagc cagcgattgg atacgcctgc tgcgtactct ggcataaagc 3381001 ggacgccgtc taagtgaccg agcgcatttt tgtatctcgt gaaaatggtc cttcttttct 3381061 ccactcgctc atccagcacc tcaagctggg caatgccgac gccggctaag atattgctca 3381121 gcctgtaatt atgtccaatt tcactgtgct gataatgaac agccggctct cgtgcctgcg 3381181 aagcgagaaa tcttgctttt tcaattgcgg cttcatcatt tgaaacgagc atccctcccc 3381241 ctgatgtggt gatgattttg ttcccgttaa atgaaaaaat gccgaagcgc ccgaatgttc 3381301 cgctttgctt ccctttatag actgtgccga gagattcggc tgcgtcctca atgacaggaa 3381361 ctccgtatgc atcacacagg cttacgattt catccatttt cgcgctctgc ccatatagat 3381421 tgacggcaat taccgctttt ggcagtgttc cgtttctttt cgcttcctcc aatgctcttt 3381481 caagggctgt cggcgacata ttccacgtat caggctcaga atcaataaag acgggcaccg 3381541 ctttttcata tagaatcgga ttggcggttg ctacaaatgt gaaggactgg caaaacacgc 3381601 tgtcaccttc ttttacctca agcaaacgca gcgcgagatg aatcgccgcc gttcctgagc 3381661 cgaccgcagc tgctgctttt acaccgactc gttctgccag ctgttcttca aatgaattca 3381721 cgagcggccc aagcggcgca atccagtttg agcgaaaggc ttctgaaata tagtgctgct 3381781 ccctgccgct catatgaggg ggagataagt agattttttt atgcatagaa tcatcctttg 3381841 tttgatgttt gaatggaaga aatgatgcgt gccggagcac cggccgccgt taccctgtcc 3381901 ggtatggaac ggatcaccgc ggagccggct ccgacaatgc tccaagcccc gattatgatc 3381961 tgcggtatga cggatgcacc ggttccgacg tgagcgcctt cctgaacgga aaccgctcct 3382021 gacagcgtgg cacgcgggga cagatgaacg taatcgctga tttgattgtc gtgctctgcc 3382081 actgcacccg tattgatgat gcagtgggcg ccgatgcgcg catccgcctg aatgatcgcg 3382141 cccgccataa tcactgtccc ttccccaatg acagccgact tgctgacgat ggctgacggg 3382201 tgaatcaatg taataaaatc atctttcccc agtcccagtc gctccgccag ctgttttctg 3382261 acactgttat tcccaacagc aatcagaaac agcacatcag gaatgagcct gcgcagttca 3382321 gtaacggctt tcggcggtcc tgtgtaccat tcttttccgc cttcgaacgt tttgaattta 3382381 tcatccagca ccgcggctaa gcgcgtatct gagcgggcgt ttatcagctc tctgatcacc 3382441 tttccgtgac cgccgtcacc cacaatggcc acatttttca tgaggacaca tctccgcttc 3382501 cggtaaaccg ttccgcggtc acatgattgg tttgctgaat cccttctgaa acaaggacct 3382561 ttcgcaccgt caaacataaa attttcaaat cgagaaaaaa tgaccagttg tcaacgtacc 3382621 aaacatctaa ttcaaatttc ttttcccagg aaatcgcgtt tctgccattg atttgcgccc 3382681 agcctgtgat acccggcttc acctcatggc gccgtgcctg tttttctgta taaagaggca 3382741 gatagtccat caaaagcggc cgcggcccga caaggctcag atcgcccttc aggacattca 3382801 ggagctgcgg aagctcatca atgctcagct ttctgatcag cctgcccgtt ttcgtcagcc 3382861 ggacttcatc aggcagcaga tttcctttac tgtcccgttc atccgtcatt gtccggaact 3382921 tatatagggt gaacggtttg ccgtgcaggc ccggccttac ttgcttaaag aagacaggtg 3382981 atcctatttt cagcctgaca acggcgatgg tgaacagaat gatcacactt gtacagcaca 3383041 acaaaaaaat ggcggccgtc agatcaaaaa gtcgtttcag gatcaaagat tcacagctcc 3383101 tttcgttttt cgaaaccgtt ttaataccag ctgtctttcc tcttttgtac aaacgagcat 3383161 aaaagcgaaa acagcgtagc aaaagctgac tgtcactccc gtcgctatca atgacggcca 3383221 gctgtcaatc ttcacaatga actgaattgc cttacagacc gtccaggcaa atacagcggc 3383281 tgaaagaggc ccgattatgc ctttaaggaa cacgtgcttt ttgtagcctg taatgcggga 3383341 tacgtaaagc ggcgtaaaga tggcattttt taaaataaga gaaatggccc ctgccaatgt 3383401 tatgccgtac agaccgagat gagccggccc gctcagcgtg accgccagca ccacattcac 3383461 cgcacctaac agcagggtaa caatcgccgg tgttttttgt tgattaaaag cggtccatat 3383521 ataaaacagc ggcataaagg cgaggctgac aaccaagtat ccggcatgaa taaataaaag 3383581 cggtgctatc gttgaaaagg acggtccgag ccagattgtc agaaaaggtc ccgccaatcc 3383641 gcccaataag gcagcaggaa gtgcaagcaa aagaccattg agccttactg ccttattggc 3383701 gtaattcatc aatccttcca tatcgccttt tgaataatat gaagtcatga tgggcgcaaa 3383761 cagggatgcg accgttccgg ccaagctgcg caaaagcagc ggaaactgga taatcgccgc 3383821 gtatttcccg gatgcagacg cccccagcat caaattggcg gttaacagat caatctgcaa 3383881 aaaaagcagg acgccgattt gattgacgga gctccatgcg cccgcttgaa acagctcctt 3383941 gcttgtacgg aatgaaagat ccttcatacg aaacgaaaac cacggaatca gctttttgaa 3384001 gaaatagaaa gacagcacag acgcaataac agcaccagct aaagctgcaa gctggatctg 3384061 ccagattttc ggcgcaaagc atgcaaacag gagcagcaca gacagcaccc gtataagcat 3384121 ttgcaccgcc tgaatggaac tggtgatata aaggcggttg gcataaaatg gtgcagcgcc 3384181 gaagcccgcc atcagaaacg ttaaaataaa cagcacactg ccgattaaaa tcgacaaacg 3384241 cacatctgcc aaaagcgctt gcggcacatt catgacgcgg tcaataaaaa aagccgaacc 3384301 cgcaagcggc agcaagagca gcaaggaaat caaaacagag gcggctaaat aattgctgat 3384361 atacgcattt gctttctccc gctctcccct gtgggcagca acagaaaaga accgaacgac 3384421 aaccgagctg agcgccacgg taataaccga aaagtaatta atcacatttt gtgtcaagtg 3384481 aacaaagcca aacgcttcga caccgagcgt tttgacaata aaaggcgtca tccaaaccga 3384541 taggaaaaca gacaagagaa aagccgtgag attcgcgctg aaatttatcg tgaatttcat 3384601 gcctgcttcg cactgccttt cattgtcccc cgctgctcga aaaacagctt gatgagaaaa 3384661 gtgagccgcc atttacacag tgctaatacc aaacgctctc ctcttaataa tttctcatgc 3384721 tgaaacggtg tatgtctgac agcctgccgc accatgtcat aggataaaat ctgtctgatc 3384781 ttctttttga tgtctttcgg cgaattcgga gaagcacagg catttgccaa aagcatcgga 3384841 agctggtgcc tgcaaatgta cacattcaaa tcttctttac atgcgcctgc taagccgtag 3384901 tgattgtaga atgcgatttt agcctgatat tgtttttgaa gatgttcatc catcgccggc 3384961 ttataaggga tttctgtcag gctgttcggg ttttcacgat aaatgtacaa tccttcatca 3385021 agcattttca cccgctccgc ttcgcgaaaa gcggacaaat taaagggaga gtcttcagca 3385081 aaacggatgt cttcatcaaa cagcagattc gccctttcaa aaagctcacg acggtaaaga 3385141 taacgccata cataccagat aaatctcgtt tcgtgagcat gtttaagctg ttcagtcatt 3385201 tctggtttcg tcagcacgcg gtttgcctca agctgcggcg gcacatatgt ccgcctgtcc 3385261 gatgactgct tgtaaaaacc gcatccgacg atgtcaagct gattttgctc cgcttcttca 3385321 gtcagcctct ggaacatggc ggatgataca taatcgtctc cgtctacaaa gccgatgtaa 3385381 gtgccccgcg cggcctttat tcccgtattt cgcgctgaac taagcccgcc gtttgcctga 3385441 tgaatgaccc ggattctcgc atcccgtttt gcatagtcct ctgcaatttc gcctgaacga 3385501 tccggtgttc cgtcattcac gaggatgatt tcaatatcag aaagcgtttg acgaagcaaa 3385561 gaatcaatgc actcttctat aaatggttca acattataca tcgggacaat aatgctgacg 3385621 agcgggatca ttgcgcttca ccgctgattt tgtcacgcag acctttaaaa tacacatctc 3385681 tcggaaagcc tgcacgggat gtttcttttg ttaaaagctc attgactgcg gctgttacgc 3385741 gctctggctc cggatgttct atcagcttca tgaacgggat gtctttaagc cattgatagc 3385801 cctccatcac cttatggtca aaggagcgaa tgacaacaca cggcgttcct gtcagcgcgc 3385861 aaaaaatcat gccatgaagc ctgtcagtga cgacggcttc tgcgctttgc agcttagacc 3385921 acagtgcttc aagttcatgt tcgcgtgtat cgcggctgac ccggcggccg atcgttgtcg 3385981 taaaggattt gatctcgccg aattcctcac atagcgcagc cttgacccgg ttcctctgct 3386041 cctcctgaag cacgctttcc tgatcctcgc gcaaacacat ataaacccct tcgcgttctg 3386101 cgggagcctt gcttctgtct aaatacagca ccatgtccgg ctgcttcaaa attgtttttt 3386161 cttgaaaatg ctgtttcata aattgatacg ttgtttcatc ccgcgccatc agcaataggc 3386221 cggggtgcgc attataaatt ttctgtgccc gtttcagctc tttgcgccct tttttcgtgt 3386281 cagaaaaatg agccgttgcc ggaagctgga caacccgata gtcatggaat gttttaatga 3386341 tgaagcggcg cgtccactcc tcataacggt ataaatcccc catgtttccg ccgccgatga 3386401 taaagaccat atcctccgga tggcgcgagc ggatcaggct ttttgctgat ttgtaaatgt 3386461 ccttcatatc gacctcgacg atgtcaaagt ccgggtattc ttgctcaaga aatgccttgc 3386521 tggcataagc aattgcgtga tctcccaaat tgtcatggga cggcagcagg gtcagtatga 3386581 tttttttctg atgtgctgcg gcctttaccg gttgatctgc cgctcccagc caatattggg 3386641 acgggtattt gacctttagc agcagccatt ctgcaaaatt gattttcaac gattgtaacg 3386701 acatgtcctc accctctgtt tctcattttg tactcgatca cccgctgata cacagccgat 3386761 gccatagcga cgaacggaat cattctgtat ttcgccatca gaagcaggca tgaccgtttt 3386821 gcgtcaaaag gagcagtacc cgtttttgaa agactttctt gaaacaccgg gtccgcgcat 3386881 atcacgccaa catttctaag cttttcaaac agccggcggc tgccgctcgt tttccattca 3386941 ttcagcatac agatgctgct gtgaagaacg ataaaggtat caagctcctt gcgatactcc 3387001 tccagtttgt tgttctcctg taaaaacgcc gcattcgtct catacagcgc aagtcctgat 3387061 tcaaacaatt ttttctgata gcgctgcaca atggaggaaa ggtgaattcg ataatgatag 3387121 agcggcgttt ttacgtagga tactgagcgg gcgaaaaaat gagccctgaa gctgaaaaac 3387181 tgatcctcga catgctccag ctcgcctcgg agcggaaacg acagccgatg ggcttcaatc 3387241 atgcttcttc tgtacagttt gttccatgaa aaccctctga ccttcccttc gaataacgcc 3387301 ttgatatagt gctccttcgg ctgatcctga taggtttggg caatgtcaga gtccatggtt 3387361 ttgccagtgt cctcaaactc tgcggcgtaa ttgcaaatga ccagatcagt ttcatcgcct 3387421 gctgtccgga gcatctgctc gcaataatca ggctcaatcc aatcgtctga atcgataaac 3387481 gcgataaatt cgccgcgtgc agcttcaatg cctttattcc gaaccgcacc gagtccctgg 3387541 ttttcctgat gaatcacctt gaacctgttg tccattttgg cgtattcttc tgcgatatcc 3387601 gggctggcgt cagctgaacc gtcattgaca atgatgattt caatattgtc cattgtctgg 3387661 ttccgcagtg attcgagaca cgttctgata tatgtttctg tgttataaac agcgactaac 3387721 agactaaccg caggtgtttc cataatgacc ggctcctcgt gcataaatta ccgggaaaaa 3387781 atcgttctgt aaggcagaac cgatgaatcg accggcataa gcaaataact gtaaagaaaa 3387841 taacaaacaa cgatagcgat atagataaga gcgttcgatt tttcatcaaa tatcctgacg 3387901 aaataaggga ctaggatcat ttgatacaga ccgaaataaa tattgaatct ggcaaaaatc 3387961 acgtcctttg tggccaaaag gccgaacaaa aaacctagca ggcacaaatt gacgacaata 3388021 tcaatttgcg gccacagact ccgcagtcgt tctttatagc aaaatgcaag gaacagcggc 3388081 agaaccaaaa cagcgatttt gatcacattc attccatttg tgttcgtcat gagccatttt 3388141 tcataatggc tgtatgagct gttttcaagt acaacgacaa acacagaaat aaatttttga 3388201 tataaaaatg tcatgccgag aaataaagcg gataggccga atatcgccgg tgaccaggct 3388261 tttcttctga caataaagta cactggaatc ataatcagcg ccgacgaatg aaagagcgag 3388321 ctgaccagca caatcaggaa atatcgcttc cagttcccgc taatgatata acggatcgcc 3388381 caaaacaaaa cagctgccac catgtattgc ctgatgccgt taaaagatgc gtaataatga 3388441 aaggttccca aaaataaaaa gacactcagc tcaaacggcc tgccatagtc ggcgagtgtc 3388501 ttcataataa agctgtaggt cacgaccgcc accgtaaaat acatgatttg aggatcttcc 3388561 gtgatgaaat tcatcagcca aaggagtgcg gtaaaccccg gatctgtcgc tgttttcgct 3388621 gtgccgaaac cgaatatctg ccacacattt tgataatcgc ccgccaattc gtacaacagc 3388681 gtgtacgtct gaaaatccgt gccgactcga tagcggagac ctgacacgag cacaagtgaa 3388741 gcgagcggaa tccagatcaa aagcttattc ggccgatacc ccgtggcaag cgaatcatca 3388801 cggccgccgc acattttagc gaaccaagac caaataaata caatccccat attgacggca 3388861 tatacaatca tcggttatgg tccttttccg tgctgatgtt gtatacattc agcagcgctc 3388921 ctacattttg ctgtgcatcg tagccaagtt gagcgagtgt ttctttgatg aactcacgct 3388981 tcggcctgcc tgcggcggcc gcccttgcaa tggtttcagc ccagacgctg atcggctcag 3389041 aaagacttaa tcttgtgaca agcccgagac cggcgtcgac tttttctgta atgctgtctg 3389101 aaatgatgca tggaagcccc gacgcctgcg cttccacaag cacaaccggc aagccttcgt 3389161 acagagacgg catgacaaat acatcgaatg ttcgcatcag ttcatggatc cgttcttccg 3389221 tgcctaaaaa gaggacgtct gatagcaaat tctgctgccg cgcctcctcc tctatctccc 3389281 cgcacaacgg cccgtctccc gccagaacga gctgaaagcg aatgcctctt tccttgagat 3389341 gtgcggcaag cttcaacagg aacgcgtggt ttttcacttc atgaaaccgg gccacatggc 3389401 caatgatgag ccggtcggct gcaatgccgc gtgctgcttt ttcttcatca gccgcctgcc 3389461 catttggggc gaacaactca aggtcaatcc cgttaggaag aaggtgaaca cgctcccgct 3389521 ccatattgga ctgtccaaat aaaaacctgc ccgcatcctc tccgcaggca cacagcgctg 3389581 tcgcatttgc caaaatgagc cgcctgaaca cgagcagctg caatcgatcc ttccagttga 3389641 agccggtctt ccaagacgta ttgtgggagt ggcataccct gaccggcact ccggcgagcc 3389701 ttgccgcaag ggcgataaaa cccgtttgga aatccgtgtg cgcatgaacg gcgctgaacg 3389761 gcccattttc ttttatcgcg tttctcacat tcctcacaaa tgtaagggga ttgctttgcc 3389821 caatgctcgg gacataaaaa agccgcccgc ctaaagataa aatctcttca tcataagcgc 3389881 acggatcatt tcgatacgtt aaaaaatcaa attgcacttt gcttttgtcc atcttccgat 3389941 ataaattcat taccatggtt tccgcgccgc ccctgttcat gccgctgaga acatggagca 3390001 cgcgcttttg gctgctattc atgcttgaca agcccttcct tttggttcat cactcttttt 3390061 ttatggtagc gattcatcac agctgcaggc ataaaggcgc gaattaacgg ttttgcgata 3390121 tatatgtaat cagataaagg aagcttcaag cgtctgcacg cctgatagac aagaatggca 3390181 ttgtcgattg aatacgtaaa tgaccgccgt ttgaatgcat cgctgtcttc cctcacttta 3390241 tacaaggctt cctgaagatt atagcccctg aagccctctt caaaaaagcg aagccacaaa 3390301 tcaatatctt ccattcgtct cgtccgccgc accgaccggt agcctttcag cgtgcggtag 3390361 gcactcgctc tcatcataat cgtgccgtgg caaaatggag tcccttttgc catgatgccc 3390421 ggctccggaa cagaaggcag aatgcgggcg cctcttacgc caaattcatc aaacacaagc 3390481 atgccggtgc caaccacctg atagtgtcgg tgcttttcta aaaacgcgac ctgcttttcc 3390541 agacggcgcg gaaacgaaag gtcatctccg tcctgacgtg cgatataatc gcctgtcgca 3390601 tgcgaaagac aatgatttaa tgatgcggca agccgcttat ttgttttgtt ttgaatcagt 3390661 ttgatgcggt cgctgtaatg agcggcatac tgcttcgcga tacggagcgt gccgtctgtt 3390721 gacgcatcat cgcacaaaat cagctcccaa tttttatagg attggctgag tatggattct 3390781 atgctttctg ccaaagtgcg ttcgcaatta taaatgccca taatgacaga aactttcggt 3390841 cctgagttca tacgcttttc tcctttgtat ccatatccat gtacgcggaa taaatatctg 3390901 ccatttcttc caccgttcgc gcctccgaga agcgcaaggc tgtttttcgg ccttcctgtc 3390961 ccagctttcg gcagagctcc ggcttatggt aaagctgttc aatccggcgg gcaaaagcag 3391021 cactgtcacc gattttgatc agaaaaccgt tttctccgtc gcggatgatt tcccgatgcc 3391081 cgcgattatc tgtggcgatc gccggttgtt ctgccgccat tccctcaagc acattcatac 3391141 cgaggccttc tctaatgctg gatgcgacag atacatccgc aagctgaatc aactcatgta 3391201 tgtcgctgca aaagccgtaa aaacagacat gggcggaggc accaagcttt tcagctaacg 3391261 tttgatacgt atgttccatt gccccttccc cggcaaacac aaggcggagt gagggaattt 3391321 tttcttttag caaggctgcg gcttcaatta actgcttctg gtttttgttc agattgagct 3391381 cagccggata aaccaatata aaatcatctt cacggaaccc gtgcttttct ctgagtcttt 3391441 gctgctctat cggactgaca ggccggaaac gctcggtatt gacgccaatg ccgtgaattt 3391501 tctgcgtcct tccgcccggc ctttgaagtc ctttcgcccg tatgtaatcc tcttcattaa 3391561 tcgtaatcag gcagtctgta tatgctgaaa gccatttctc aaccggatag taaagaagcc 3391621 aatttttcat cggtgcccct ttgcagaagt gaaatccgtg cgctgtgtac agcacctttg 3391681 ttccgtgccg ccgtgcctgc ctcgccgcca gtctggcgag aacgccgccg accggtgtat 3391741 ggcaatggac aatgtcgtat tcataagtgt caatcacttt cttcagctgc ctataaacgg 3391801 ccaggttctg agggtcaaaa ggtgacctgc gaatcgggat ggagaatttc tcatccacat 3391861 acggcagctt ggtttgtccg ttcgcggcga catgaacctc ccagcccatt tgcttgaacc 3391921 atttaaaata agggaggtga aaggccttaa aatgataatc aacagtcgcg caaaacaata 3391981 tctttttcgt cattttcact ccccctaatg aacgctggca gccgtcattt cttctgatgt 3392041 attgattgcc gcaaacagcc tcgctctcag gtcggcttcc ggcagctcat gaaaatcctc 3392101 gataaagcgc atcagcaccg gccaatcgcc gtccaccgct ttaccgatgt gaatttttgg 3392161 aaagatttgt tcagcatgga cttcattttt gttcagcaat tcttcataca ttttttcgcc 3392221 cggacgaatg cctgtgaatt cgattggaac ctgctcagtc gtgtagccgg acaaatgaat 3392281 gaggtttttg gcaagatcca caatctttac gggctctccc atatcgagaa cgaaaatttg 3392341 acgccctttc gccagtgccc cagcctgaat cacaagcctt gatgcctcgg gaatcgtcat 3392401 gaaatagcgg gtcattgccg gatgtgttac tgtcaccggg ccgccttttt caatctgttt 3392461 tttgaaaatt ggaatgacgc tgccgcggct cccgagtaca ttgccgaagc gaacagcaac 3392521 aaatttggtt ctgctgactt tcccaagatt cataataatc atctctgcga atcgttttgt 3392581 cgcccccatt acgttggctg ggttcaccgc tttgtccgat gaaatcagca cgaatgtctc 3392641 agttcccgac atatcggctg cttccgcgac attttttgtt ccgataatat tgtttttgac 3392701 cgcctcttct ggattgtgtt ccattaaagg cacatgctta tgggcagctg catgatagac 3392761 aacatgcggc tcgtattttt tcatcaaggt aaacatttta tcgcggtcct gcacatcagc 3392821 gatttccgta tggaacacaa tgtgtttgcc gaatcgtccg ttcagctctg tataaatcga 3392881 atgaatgctg ttttccccat ggccgagcag aatgatttcc ttaggctgaa acgcgctgat 3392941 ctgacggcag atttccgagc cgattgatcc gcccgctccc gtgacgagaa ctgtttttcc 3393001 tttgatgcgg ttcgaaattt cgctagtgtc gagggttacc ggctttctgc cgagcaagtc 3393061 ctcagctttt acatctctga tttgtccggc agttcgtgtg ccaagcagca tttcatcaaa 3393121 atgaggcata attttaatgc ttactccggt tcgcacacat tctttatata acacctgaag 3393181 ctcatgggtg cggagtgaag gaatggcaat aataatataa ttaattttga gcttttgcac 3393241 cgcaggcatg atactttctt ttccgccgat tacgggcagc cccataattt ctaatttatg 3393301 cttcgtttgg tcgtcatcaa taaaagcgac aggtatgata tcaggttcat ctttcgaaag 3393361 cagctgcctg accatcagag tcccacctga gcccgccccg ataatcagcg cgcgggacga 3393421 ggcgcagcgt tttttcctga tgctttcgtt taatactctg gataaaatac gggtccctcc 3393481 aatagacaaa agctgaagca cccagcacgc ggttaacaga cggaagaaca tcgtgtgata 3393541 cacagcatac tgaatgacgc cggtcacagc ggctgaaagc gtaatgccct taagcaggac 3393601 aatcagctcg ccaagcccgg tgtatgtcca cacctgttta tactgattga acaggaaagc 3393661 acacacatga tagctgagga gcaagctgac agcggtaagc agtaatgctc cggagtcata 3393721 aaattgatag gaatctttta aaaattgata tcctgcaata actgaattta aaacgaggta 3393781 agtatccagc gcaataatca ttgacagtct tctccggtaa ctcaaccttt tcccccctaa 3393841 ttcttttatc ggtttagctg cggcggtttt cgtctctcca aaaaatcggc agcagctaaa 3393901 ccgacaatac gtcctatgta tatatgagat aagtgggcat ttaacccatc ctcacgcccc 3393961 gccagcgacg accagcatct aaggcagcaa cttcagctgc ccacagcaga gccgagtgcc 3394021 tccattgata caggtcagga gacatcacct ttacaaaaac tagtaggaat agtgttccga 3394081 ttttttcatt ttctttttgt ttaaaagagc gcctaacagc ttcgcattgg attgttccag 3394141 tgcatctttt gctttcagaa cggtatcggt ttttgttttt ccgcttaaaa cgacgagcac 3394201 gctgccgtct gtctgatttg ctagaatctg agcatctgca acagccaaaa gaggagggga 3394261 atcaaagatg acgaggctga attgttcata gatctcagat attaaatctc ccattgcttt 3394321 tgaagacaac agttctgccg ggtttggcgg ggtcggcccg cttgtcagta catataagtt 3394381 atcgatcggc gtcttttgca ccgtctcact gagtgaagca ttgccgacca gcacatttgt 3394441 cagcccggtt acattatcaa cctgaaacgt ctgattgatg gtcggctttc ttaaatcggc 3394501 atccaccagc agtactttct tttcctgctg ctgcgcaaag acagccgcaa gattcgctgc 3394561 actgaacgat ttaccttcac caggcacaga ggaggtgacg aggatagatc gcaagttggt 3394621 ctggacagat gagaactcaa tgtttgtccg aatggtgcga tattgttccg caacaactga 3394681 tttattgtgt aaaacagata tttgagccaa acctcgcctt gctttctttt ttctaaagat 3394741 cactcgcttc actccccgaa atgttttatc ccgcgattcc gccctttgtg gacatcagga 3394801 acggagccta agcatggcaa tccggttctc tcgctgagct gccgtgcgct tttgcatgta 3394861 tcatcgagaa aatgcagaaa aaatgccagt gtaatgccgc ccatgacagc agcgccaaaa 3394921 gccatgacca tatttcgcag cctggccggc ttgatcatcg ggctttccga agccttcgcc 3394981 tctgataata tatgtacgcc ttgtacattc attctttcat ctacttcttt ttcaaacttg 3395041 ttcactaacg tgttcgcaat ctcagctgct ttcgccggat cgtgatcctg aacggcaacg 3395101 ttgattattt ctgattcatt ttcactgctg gtaaccactt ttcctttcag cgaggaagcc 3395161 gattcagata ggtgcaattc cgccttaact tcttccatca aggcagtgct tttcataatc 3395221 gattggaacg tgctgctata ctgaagattt cgctggatgt cactgagatt cgagttttct 3395281 tcaccgtctg attcatgaac cagcacctgt gtcgacgcct ggtaggtcgg tgaaatgacc 3395341 ttaaattgca caaaacccat aataagggtg acgccgattg tgatgagcag aatcagcacg 3395401 aatctgtgtc tgacaatcgc atataattct ttgaaactca tattctcatt catgtattca 3395461 tagccttcag ccttcccgcg gctggcttcc cgcgcccctt tctgttaatg attggattat 3395521 aaaagaaaac gttattattt aaaaattgca aaataagcca ataagttctc tttagagaac 3395581 aaaatcatga ttttcctcta atttactgca cttcccttat tattttaaat tttataaaga 3395641 acgaaaaatt ccttataatg aacgaaataa cgacaggaat agaggagaat ttcatattat 3395701 gattggaaga attatccgtt tgtaccgtaa aagaaaaggc tattctatta atcagctggc 3395761 tgttgagtca ggcgtatcca aatcctattt aagcaagatt gaaagaggcg ttcacacgaa 3395821 tccgtccgtt caatttttaa aaaaagtttc tgccacactg gaagttgaat taacagaatt 3395881 atttgacgca gaaacaatga tgtatgaaaa aatcagcggc ggtgaagaag aatggcgcgt 3395941 acatttagtg caagccgtac aagccgggat ggaaaaggaa gaattgttca cttttacgaa 3396001 cagactcaag aaagaacagc ctgaaactgc ctcttaccgc aaccgcaaac tgacggaatc 3396061 caatatagaa gaatggaaag cgctgatggc ggaggcaaga gaaatcggct tgtctgtcca 3396121 tgaagtcaaa tcctttttaa aaacaaaggg aagatgatga tcggttaaag ggctaacgtt 3396181 cgcatctata ggggaaatct gtttataatg ggggaaaaag ggagagaaca caatgactca 3396241 tcaaatagta acgactcaat acggcaaagt aaaaggcaca acggaaaacg gcgtacataa 3396301 gtggaaaggc atcccctatg ccaagccgcc tgtcggacaa tggcgtttta aagcacctga 3396361 gccgcctgaa gtgtgggaag atgtgcttga tgccacagcg tacggctcta tttgcccgca 3396421 gccgtctgat ttgctgtcac tttcgtatac tgagctgccc cgccagtccg aggattgctt 3396481 gtatgtcaat gtatttgcgc ctgacacccc aagtaaaaat cttcctgtca tggtgtggat 3396541 tcacggaggc gctttttatc taggagcggg cagtgagcca ttgtatgacg gatcaaaact 3396601 tgcggcacag ggagaagtca ttgtcgttac attgaactat cggctggggc cgtttggctt 3396661 tttgcacttg tcttcattta atgaggcgta ttctgataac cttgggcttt tagaccaagc 3396721 cgccgcgctg aaatgggtgc gagagaatat ttcagcgttt ggcggtgatc ccgataacgt 3396781 aacagtattt ggagaatccg ccggcgggat gagcattgcc gcgctgcttg ctatgcctgc 3396841 ggcaaaaggc ctgttccaga aagcaatcat ggaaagcggc gcttctcgaa cgatgacgaa 3396901 agaacaagcg gcgagcacct cggcagcctt tttacaggtc cttgggatta acgagggcca 3396961 actggataaa ttgcatacgg tttctgcgga agatttgcta aaagcggctg atcagcttcg 3397021 gattgcagaa aaagaaaata tctttcagct gttcttccag cccgcccttg atccgaaaac 3397081 gctgcctgaa gaaccagaaa aagcgatcgc agaaggggct gcttccggta ttccgctatt 3397141 aattggaaca acccgtgatg aaggatattt atttttcacc ccggattcag acgttcattc 3397201 tcaggaaacg cttgatgcag cgctcgagta tttactaggg aagccgctgg cagagaaagt 3397261 tgccgatttg tatccgcgtt ctctggaaag ccaaattcat atgatgactg atttattatt 3397321 ttggcgccct gccgtcgcct atgcatccgc acagtctcat tacgcccctg tctggatgta 3397381 caggttcgat tggcacccga agaagccgcc gtacaataaa gcgtttcacg cattagagct 3397441 tccttttgtc tttggaaatc tggacggatt ggaacgaatg gcaaaagcgg agattacgga 3397501 tgaggtgaaa cagctttctc acacgataca atcagcgtgg atcacgttcg ccaaaacagg 3397561 aaacccaagc accgaagctg tgaattggcc tgcgtatcat gaagaaacga gagagacgct 3397621 gattttagac tcagagatta cgatcgaaaa cgatcccgaa tctgaaaaaa ggcagaagct 3397681 attcccttca aaaggagaat aaatatgggg aaaacaggat acattggtgc tgccattgtt 3397741 gtggcagctt gtatcattat tttgtcggcc gtggtatgtt tacgggacac agtctattac 3397801 cagcctatgc gctggactgg catcatactg tttttcgcgg gaattgtgat ggttcccgca 3397861 tactcagcaa aaagaaaacc cggaaaagag aagtaattct cttttccggg tttttatgtt 3397921 tattataatc ttcccgcgcg aatatcgtct gtcattccct cataaggagc cttcgaaatc 3397981 acttcttcgt tgtcgactcc ttcatttttc agaaatgtaa tttccgcaaa ttcaggtaca 3398041 acgtattttg gatacgtttc atatttttcg cgggattctt tcatcaaatc aatgtggtca 3398101 ttttggtagc aaaccgtaat ttcaggatgt tcatgcaccc atttcgggaa gaaaataatg 3398161 ccatgcatgc gtttttcatt tggcataaag tttaatgaaa catccgtgcc agtcggctct 3398221 gtccaagaca ctttatatac gccttctgtc agtttgacaa tattcacttc ctgatctcga 3398281 acccagcgtc cggcaaccat tccgctatga attctataat caattgtatg gtcgttttta 3398341 atataaatct cgtattccca tccgttttca tacgtataaa tcatgtggct tccgataaag 3398401 ttttccatct tacacactct ccttagtctt ttactgtact tcataaatgt ctagtagaac 3398461 gtaatcaggg gttctttctg cggaaccgat aaacaagcgg tcatggagcc attgatagac 3398521 ttcactgcct gtttcaaacg tcggtaccgt acgaaaataa acatgctccg gttcaataat 3398581 ttccccggct gccgcttgtt ttcgaaacgg cttgctgact tgccgtattc cattgttttc 3398641 aatgtaaatc agttcatgat ctgctgtttc aatcacatac ctggcagata aatctgttct 3398701 gccgttagcg cgaatcattt gtgaatcggc accgcccggc aaaatacgtc cctttacttc 3398761 cccggttatt gttcccgaac gaatcggaat gaatcatctc agtcccaggc ttgtctcacc 3398821 aatcgtgata ggcggatcaa ccttgatttc taaagaggcg aatggtttta aaaccggctt 3398881 cttcacgaga accacctcac cttcagaaaa aatcatgtaa ctatttacat gttcacttta 3398941 acaccattgc agttaactgt caaacaatag gaacataaaa aaacaaggac tgtttgaaga 3399001 cagtccttgt ctgaagctag ctttgataag caagatatgt gctgacagtg cttttggcaa 3399061 gacaggcaga ggaatctata atcggaatct cactttgaat atgatctaac accgcattta 3399121 aatccgtgca ggctgaaatg atgatgtctg catgctgact gatttcttca tatagcgtct 3399181 gccacaatgc ttgtgtatgc tgcatatgat ttggctgttt gattgcggcg ataagctggt 3399241 tcacagcctg ctgccaatgg tccttgtgaa taacttcttg tccatttccc ttcagaactt 3399301 tttggtagat ggcggattgg atggttggct ctgttcctaa aaccaccgct ttttttgcgg 3399361 gatgcggaat ctcttttatc gtttcctcaa caatatgcaa cataggaact gacaatgcct 3399421 gctgaatctc ttcatagtag acatgcgccg tattacaagg cagcgcaatg aaatccacgc 3399481 ctgttttctc gagctttacc gctccgtcga taatcgcttt tttcatctcg tcatggtcaa 3399541 ttggacgatc tgcatagaag ggcgtcgggc atgaatagat catcatgtgc ggatagtcaa 3399601 tatcgtttga agccccatac agcttctgac agtaatcaat caccttatca ataaacggcg 3399661 aggtcgattt cggccccatt ccggctaata ttccgatcat caaattcatt cctttctact 3399721 tcgtacggac cgcttcttcc tctgagccat cctcatagag gataaagctt ttcgcagcat 3399781 cctcacctaa tgtaaactcg acttcaacag acaatgctcg cagaaagaaa cgggtttccg 3399841 aggaaggaaa taactccagt ctcagctgtc cggcgatctc caaataaagc cgttcattct 3399901 cggttgtcac ctgtgcagcc gtcccatcct gcaacaggta gctgccaaca tagcggctgt 3399961 atatcgccgt atcaattgct tttttctttt tatcagcagg acgttccggg acatcatatg 3400021 gctggccaaa tagaatatgt tccgccgcct tcagaatcgc ttgttcatat tcagtatcct 3400081 cttccttatt actcaaatag atcagcgttt tacgatgatc gatatatcgg atcatcatcg 3400141 tcgaatagcc gggccatcct ccgctgtggc tgacaatccg ccctttttca ggactgtttt 3400201 gcagcaccca gccaaagcca taatcaattg tttctccatt gttgaggcgc actggagaaa 3400261 acgcagattc cttagaagcc ttgctgatga aatcgtcctg atataaagcc tgatcaaatc 3400321 gaaacaaatc gcttgtgaca gagttaaccg tcccatctcc ctgtatgcca tcgagataca 3400381 caacatagtt cgtttcctcc agctcatcag ggaggacgta tgtttcggaa tgtacatcat 3400441 acacatatcc atatgcataa tgatcaattc gctcaggcga aagcctcctg ttatacactc 3400501 ttgtttcatt catgcctgcc ggtaaaaaaa tacttgtttt tataaaatcc gcatagctca 3400561 tgccagatgc tttttcaatg ataaccgcca gcagcacata ccccgtattg ctgtacatcc 3400621 agccttcatt cggttcaaaa taaccagata gcccctcatt catcagcata tcgacaatat 3400681 cctgattcac cgcaatcttg tgtgaatccc aattggcaaa aaaccatccc atataatcag 3400741 gaagccctga cgtatggttc aataaatgcc gaatcgttac gccctgatac ggaaaaccgg 3400801 gcagccagcg atccacttta tcctcatagc caagaatccc cttctcctcc agcaagatga 3400861 ttcccaatgc tgtaaaaggc tttgacaaag acgctaactc aaacaaagag ttggttttca 3400921 acgggcgttt ttccgtcatt tccgcatagc caaaagagtg gtgatataaa atatcgccac 3400981 cctccgcagc cagaaccgtc ccgttaaact gatgtttttc gcctaatgtc tcaaataacg 3401041 tctgaagatg ctttctttta ttctgcttca ttcctccacc tcccatatct ctgtacgtta 3401101 ctaacctact aacgtttcaa atattttgaa aaatccttca gttagagatc ctttttaacc 3401161 catcacatat acctgccgtt cactattatt tagtgaaatg agatattatg atattttctg 3401221 aattgtgatt aaaaaggcaa ctttatgccc atgcaacaga aactataaaa aatacagaga 3401281 atgaaaagaa acagatagat tttttagttc tttaggcccg tagtctgcaa atccttttat 3401341 gattttctat caaacaaaag aggaaaatag accagttgca atccaaacga gagtctaata 3401401 gaatgaggtc gaaaagtaaa tcgcgcgggt ttgttactga taaagcaggc aagacctaaa 3401461 atgtgtaaag ggcaaagtgt atactttggc gtcacccctt acatatttta ggtctttttt 3401521 tattgtgcgt aactaacttg ccatcttcaa acaggagggc tggaagaagc agaccgctaa 3401581 cacagtacat aaaaaaggag acatgaacga tgaacatcaa aaagtttgca aaacaagcaa 3401641 cagtattaac ctttactacc gcactgctgg caggaggcgc aactcaagcg tttgcgaaag 3401701 aaacgaacca aaagccatat aaggaaacat acggcatttc ccatattaca cgccatgata 3401761 tgctgcaaat ccctgaacag caaaaaaatg aaaaatatca agttcctgaa ttcgattcgt 3401821 ccacaattaa aaatatctct tctgcaaaag gcctggacgt ttgggacagc tggccattac 3401881 aaaacgctga cggcactgtc gcaaactatc acggctacca catcgtcttt gcattagccg 3401941 gagatcctaa aaatgcggat gacacatcga tttacatgtt ctatcaaaaa gtcggcgaaa 3402001 cttctattga cagctggaaa aacgctggcc gcgtctttaa agacagcgac aaattcgatg 3402061 caaatgattc tatcctaaaa gaccaaacac aagaatggtc aggttcagcc acatttacat 3402121 ctgacggaaa aatccgttta ttctacactg atttctccgg taaacattac ggcaaacaaa 3402181 cactgacaac tgcacaagtt aacgtatcag catcagacag ctctttgaac atcaacggtg 3402241 tagaggatta taaatcaatc tttgacggtg acggaaaaac gtatcaaaat gtacagcagt 3402301 tcatcgatga aggcaactac agctcaggcg acaaccatac gctgagagat cctcactacg 3402361 tagaagataa aggccacaaa tacttagtat ttgaagcaaa cactggaact gaagatggct 3402421 accaaggcga agaatcttta tttaacaaag catactatgg caaaagcaca tcattcttcc 3402481 gtcaagaaag tcaaaaactt ctgcaaagcg ataaaaaacg cacggctgag ttagcaaacg 3402541 gcgctctcgg tatgattgag ctaaacgatg attacacact gaaaaaagtg atgaaaccgc 3402601 tgattgcatc taacacagta acagatgaaa ttgaacgcgc gaacgtcttt aaaatgaacg 3402661 gcaaatggta cctgttcact gactcccgcg gatcaaaaat gacgattgac ggcattacgt 3402721 ctaacgatat ttacatgctt ggttatgttt ctaattcttt aactggccca tacaagccgc 3402781 tgaacaaaac tggccttgtg ttaaaaatgg atcttgatcc taacgatgta acctttactt 3402841 actcacactt cgctgtacct caagcgaaag gaaacaatgt cgtgattaca agctatatga 3402901 caaacagagg attctacgca gacaaacaat caacgtttgc gccaagcttc ctgctgaaca 3402961 tcaaaggcaa gaaaacatct gttgtcaaag acagcatcct tgaacaagga caattaacag 3403021 ttaacaaata aaaacgcaaa agaaaatgcc gatatcctat tggcattttc ttttatttct 3403081 tatcaacata aaggtgaatc ccatatgaac tatataaaag caggcaaatg gctaaccgta 3403141 ttcctaacct ttttaggaat attgctgttt atcgacttat ttccaaaaga agaacatgac 3403201 caaaaaacaa aatcaaaaca gaagccggac taccgggcgg catatcattt tacgacgccg 3403261 gataaatgga aaaatgaccc tcaaaaaccg atctattttg atggcaagta tcattatttc 3403321 tatctatata accgggatta cccaaaaggc aacggcacag aatggcgcca tgccgtctca 3403381 gaggatttgg tgcactggac cgatgaaggc gtggcgattc cgaaatatac aaacccggac 3403441 ggtgatattt ggaccggttc cgtcgtggtg gataaagaga acacagccgg cttcgggaaa 3403501 aatgcgcttg tcgcgattgt gacacagccc tcagccaaag acaaaaaaca ggaacaatat 3403561 ttgtggtaca gcacagataa gggaaaatca ttcaaattct acagtggcaa ccccgttatg 3403621 cctaatccgg gcacagacga tttcagagat ccgaaagtca tatgggatga ccaagataac 3403681 aaatgggtca tggtcatggc tgaaggatca aaaatcggct tttatgaatc cgataatctt 3403741 aaggactggc attacacaag cggattcttc ccagaacagg cgggaatggt ggaatgtccc 3403801 gacctctaca tgatgcgggc aagcgacgga acgaataagt gggttctcgg tgccagcgcg 3403861 aatggcaaac cgtggggcaa accaaatacg tacgcctact ggaccggaag cttcgacgga 3403921 aaagaattca aagcggatca gactgaagcc caatggcttg actatggctt cgactggtat 3403981 ggcggtgtga cgttcgaaga cagcaaaagc acagatccat tagaaaagcg gtatgcgctt 3404041 gcctggatga acaattggga ttatgccaac aacaccccga caatgaagaa cggctttaac 3404101 ggcacagatt ctgtcatacg cgaactccgg ctgaaggagc aggatggaac atacagcctc 3404161 gtctcacagc cgattgaagc tttggagcag ctgactgttt caactgacga aatagaggat 3404221 caggatgtga acggatcaaa aacattgtcg ataacaggtg atacgtacca gcttgatacg 3404281 gatctttctt ggtcagagct aaagaatgca ggcgtcaggc tcagagaatc agaagaccaa 3404341 aaacgccata ttgatgtcgg cattttcgct gaaggcggct atgcttatgt caatagagca 3404401 gccacaaatc agcctgacaa aagcaatacc tatgtcgaaa gcaaagctcc ttatgatgta 3404461 aacaaacgta aggtgcattt gaaaatactt gtcgataaaa caacgataga agtatttgtt 3404521 ggcgacggga aaaccgtttt ttcaaatgaa gtcttcccaa agcctgaaga taaaggaatt 3404581 accctttatt ctgacggcgg cacagcctcc ttcaaaaata taacagtgaa acactttgat 3404641 tcgattcatg aataaaaaca ggggcggcgc aggctgcccc tgttttttta ttaggagcgg 3404701 tattctctgt tacatattgg gcattgtaag gaatataagg ctggtttcaa aggaggaagc 3404761 gaatgtctaa acaaggaaat tttcaaaaat caatgtcgct gtttgatctg attttgattg 3404821 ggatgggagc catctttgga tcagcgtggc tgttcgctgt cagtaatgtc gcttcaaaag 3404881 cagggccctc cggcgctttt tcctggatcc tcggaggagc cattattttg ttaatcgggc 3404941 ttgtatatgc ggagctcgga gccgctctgc cccgtaccgg aggcatcatt cgataccccg 3405001 tttattcaca tggccacctt gtcggctact taatttcgtt tgtcacgatt gtcgcttata 3405061 caagcttgat ttcaattgaa gtgacagctg tgcgccagta tgtggcctat tggtttcccg 3405121 gcctgaccat taaagggtct gattcgccta ccatttccgg ctggatcttg cagtttgccc 3405181 tattatgctt gtttttcctg ctgaattatt ggagcgtcaa aaccttcgct aaggcgaatt 3405241 tcatcatatc gatttttaaa tatattgtgc cgattaccat cattattgtg ctgatctttc 3405301 attttcagcc ggagaattta tccgttcaag gatttgcacc gtttggattt acaggtattc 3405361 aggctgccat ctcgacaggc ggcgtcatgt ttgcgtatct cggcctgcat ccgattgtat 3405421 ctgtagcagg tgaagtccaa aatccaaaac gcaatatccc gatcgcttta atcatttgca 3405481 tcatcgtttc aaccatcatt tatactgttt tgcaggtcac ctttattggt gcaatcccga 3405541 cagaaacact gaaacatggc tggccggcaa ttggccggga gttctcattg ccgtttaagg 3405601 atattgcggt catgctcggg ttaggctggc ttgcaacgct tgtcatttta gacgccattc 3405661 tgtctcccgg aggaaacggg aatatcttta tgaatacgac atcccgcctt gtttacgcct 3405721 gggcgcgtaa cggcacatta tttggcatat tctcaaaggt caataaagat acggggacac 3405781 cccgcgcttc gctttggctt tcgtttgccc tgtccatttt ctggacactt ccctttcctt 3405841 cgtggaacgc gctcgtcaat gtctgttcag tcgcgctcat tctttcatat gcgattgcac 3405901 ccatttcttc agctgcgctg agggtcaacg cgaaggactt aaacaggccg ttttatttaa 3405961 agggaatgag cattatcggg ccgctttcct ttatatttac agcgtttatc gtgtactggt 3406021 caggatggaa aacagtctcc tggctgctcg gttcacaact cgtgatgttt ttgatctatc 3406081 tctgtttcag caaatatacg cctaaagaag atgtcagcct tgctcagcag ctgaaatcag 3406141 cctggtggct tatcgggttt tatattatga tgctgatctt ttcctacatc ggttctttcg 3406201 gacatggttt agggattatc agcaatcccg tcgacctcat tttagtcgcg atcggctcac 3406261 ttgcgattta ttactgggca aagtataccg ggctcccaaa agccgccatt gattatgata 3406321 aataaagaag caagaggttt tcttgcttct ttattcttta caaacaaaca tacacgcgat 3406381 aaaatgaatg agagtcagtc attactggag gtgttcctca tgccaaaaca aacatcgggt 3406441 aaatacgaaa aaatattgca ggcggccata gaagtcattt ctgaaaaagg cctcgacaaa 3406501 gcttctattt ctgatattgt caaaaaggcc ggcactgccc aaggaacatt ctatttgtat 3406561 ttttcatcta aaaatgccct cataccggcc attgcagaaa atctcctcac ccatacactt 3406621 gatcaaatca aaggtaggct ccatggggac gaggattttt ggaccgtttt agatatatta 3406681 attgatgaga catttctcat tacagaacgc cataaggata ttattgtcct ctgttattcc 3406741 gggcttgcga tcgaccactc catggaaaaa tgggagacga tctatcagcc ttattattcc 3406801 tggcttgaaa aaatcatcaa caaggccatt gcaaaccatg aggtaacgga aggaatcaat 3406861 tcaaaatgga cggccagaac gattatcaac ttggtcgaga atactgcgga acgattctat 3406921 atcggatttg aacaagatga aaatgttgaa gtgtataaaa aggaaatttt cactttctta 3406981 aaacggagct taggtactgc ttaaaaaatg actgggtaac accgctcatt ttttaatgcc 3407041 ctaaaaatga ctgacgttca ttcataaaat agagaggtgt ttcatttgaa ttgggttctt 3407101 gtttttattg cagggctttt agaggttgtt tgggcctctt ccctcaaaca tgccgattcg 3407161 cttttggatt ggatcatcat ttttatctta atcgcggtca gctttatcct gttgatccgc 3407221 tcttatcaaa aaatcccgat ggccgcggcg tacactgtgt ttgtgggaat cggaaccgtc 3407281 ggaacatatc tgactggaat tgttctgggc gaatccttct cagcagccca aatgttcttt 3407341 ttagctttat tgctggctgg cattttagga atgaaattat ttacgaaaga aagcaaatct 3407401 cagccgggag gtgaaaaata atggcatggt ttttattagt gattgccggc atagaagaaa 3407461 ttatagctgc cattgccatg aaatatatag acggaacaag aaaaaaatgg ccgatcattg 3407521 tgatgactgt tggattcggc ttatcctttt actgcctgtc ccaagcgatg atcgtcctgc 3407581 ctgccggagt cgcatatgcc gtctggactg gcattggaag cattggtgtt tcggcggtcg 3407641 ggctcatctg gtttaaggag cggtttcagc tttcacaggt gatttcactt tgccttatcc 3407701 tagccggcgt catcggcctg cgtcttacgt catcttcata aaatcaaggc atatacagct 3407761 gtatatgcct ttgccattaa gcttcgtgat gtttttgaag atgaagcggc ggcgggatga 3407821 gccagccttt gttttttagc agccttaagt attttgcgcc ggttgccgct ttcgacatat 3407881 gaaattgccc aaacatcatg gcaatatcct cacgaatcga ttgccccatc attttgctgc 3407941 atgtcacaag acctgcagca ttttctgctg ccgcggaagc cgccacatcc ggatcgagaa 3408001 accgtgcacc aggcggaata tcgttaagat ctgctgtcgg cggttcagga gaagccggcg 3408061 gcagcgccac cccgttttct ttcaggatcg tgctgacctg tttgatttca tcttggcatt 3408121 tctcaataga ctcacgaagc agcttcttca ggtcgtcatc accgacatga ttcaatagca 3408181 tttggtaatt gccgaccatt ttattgcccg ccatcacata actccacaag ccgaatacct 3408241 caccgtaatg catcggttca tcctgcggat ttccgcttaa aatacccatg ctcattctcc 3408301 tcccatattc aatattgcac atttcataac gtgcccaagc ggaggaacat ttatgtttca 3408361 gcggaaaaga tttatgaaat gaaacaaaac aaaaaagaca agagtggcaa gttgccaaac 3408421 cattgtcttt cctgttgttt gattggacgc actgaaggga ttcgcacccc gacagacaag 3408481 ataccggaaa ccattcaagt gctttttagt atgagtcatt gattctgtct ttaataaact 3408541 ttaacgagat ggcgggatgc tttgcggaaa acgaaataca ttttcggggt catatttcgc 3408601 ctttatttct cgaagccgcg caaagtttgc gccataatat tcttttccga agttttcaat 3408661 gttttgatct ggaacattaa catatgaacc tgctacatat ggttgcatca gctgacgcac 3408721 tctttcaact gatgcaagat ttgaatcttc ttgtgattta tttttccaac tagccgtcca 3408781 ttccgtataa aataatggat ggcgccaaaa aaaggcagtt tcgtctttag ggactctgct 3408841 tatagcacca ccccaattga taaaaaagaa attggcttct gttccagtag catcttccaa 3408901 aaattttctc atgattgaaa tgggttcgtc agaccaaaaa tcatgacccc atgccgagga 3408961 gaatttaaca ctctgatcat ttctgccagg gatgggttcg tcagggtcta agaaatctat 3409021 agcatctgga tagtataatg ttttgatatc tgcttctgtt ggagttcccg catgtaataa 3409081 aggttttaat aatcgaatca attcagtttt cgaaccgagg aaaattcctt ctgcatgaca 3409141 caaaccattt attttgctgt aaatttcaag gtagcatcct aatcgttcat ctacaaacgg 3409201 agcccatttc tgccaagctt taaataccgt ttctaattgt tcccacggcc agataatatt 3409261 gaagacggtt gcagttttag gggcacgatg aactttgaat gtatattggg tattatatcc 3409321 aaagttacct cctcctccgc ctctagaagc ccatagcaaa tcctcattgt gagattgatc 3409381 tgcgtgaata atccttcctt ttgcatctac cgttttcagc gcgagaaggt tatcacttat 3409441 aaggccaatc gatcgtgaga gtacaccaaa tccgccgccc atcgtaattc ccccgattcc 3409501 aactgttggg ctatctccaa acggagccat aaaaccgtct cgagctaatc cctttacaag 3409561 cgggccaacg ggaataccag tttgaacggt tgcaatagcg ttttcttcat ctaagaaaac 3409621 tttattcatg tcactcacat caataacaat tcctccactt actactgaaa ggttcttatc 3409681 taaagcatgg cgaccgcttc tgacacgtaa gggcacttta ttctcacgag cccatttaat 3409741 ggcattactt acatcgtatg aattttgcgc aaaaacaaag acaagaggat agacatccac 3409801 ataagggttc caattcttaa tagcctctgt atagccgggg tctcctttga agattacacg 3409861 ccctgtcaac tgtgttgatc ccatatatta tttcactccc aaagaaattc gattcagata 3409921 ctaaaatatg caggagctgg ataatcgcat agacaaatga tctacgaact ataaatataa 3409981 tacgctaagg cctttttcgt cggtgaggtc tgctgagaaa catttttcaa acaattttga 3410041 gcaaacttcc tgtccaatcc tccaacaagc gttttttctt atcgttttta ggagcagtgt 3410101 ccagtttttt tcggagtgaa tattcgttta ggccaaaaga aaagagagat gaagaagtgt 3410161 ttagtaccag aggtatacat ccatacaaca gactctagat catcatatac tgaatgtatg 3410221 tagaaaggag acatcagctt tggcaaaata tcggattatg acctttgacg gcggcggtac 3410281 cttaggtgct ttaagtttac aactattaaa cagattggct aggcaaaacc cgaagttaat 3410341 tagtcgaacc catgtatttt cgggaaattc aatcggttca tttactgccc ttgcattagc 3410401 aagcggaaga tctccgaggg aaacacttca gtattttgag gatgaaatcc tacccgcatt 3410461 cagcatttcc cggccaggcg gacctgtttt caaccaacaa ttaccctatt ccggttttat 3410521 taaagcggta agaaattttt tcccagcaga tcttcaactt atagatttaa gaaaacgaat 3410581 tgttgtccca tcattcaaat tatactctca aaaactggac cgttggactc ctgtcttatt 3410641 tcacaatttt cccggctctc cctatttaaa tgaaaaagtg agtgatgtca tactgcggag 3410701 cagcggtgct cccgcgacgc aacgcgccta tcaaaactat gtggacggat atgtagtagc 3410761 aacgaatccc agtacagcca gtatcgcgtt tgcagttggt aaagccaacg tgccattgga 3410821 tcaaattgcg gtattgtcca tcggaacagg tgaagccccg actcggttaa gaagagatac 3410881 gaggggatgg ggaatggtaa gtgcagataa catacgtccc gaaaatctga agaaccttcc 3410941 tccaaattgg ggagtccttt tggacaggtc gcctaatgaa cctttactgc catttcttca 3411001 gatgattgct ggcggtaatg ggtactatga atccatggtc agtgcgaatc ttctgggaga 3411061 tcgttttttc cggttagatc cgcggattcc gaacttctcc aaaacggacc ctgccgtcgt 3411121 tcccgctgtc attgaaattg cgaacaaaac aaacttacag cctgcgaatc aatttataga 3411181 gaagaactgg gggagcaaat aattatttat tttaaatcaa ttctcgctta tacaattttg 3411241 tccgagagaa gattctcaaa ataaatacag gcaatgggta gaaccggatt tttttaaagg 3411301 tttgttaatc acaagctaat aagatgaatg aaaaaatcaa ttcatacttc ttcttttgaa 3411361 agtgagggtt caaactaaag aatgtaattg aaatgttact ctaaggtatg caattccctt 3411421 tttcacacaa aaaaagacaa gagcggcaaa tcgccaaacc cttgtctttc ctgttgttct 3411481 attggacgcg ctcggaggga ttcgaacccc cgacagacgt ggtaccggaa accaccgctc 3411541 tatccaactg agctacgagc gcatatagac tgcgttatga gaacgtcagc acaactaatt 3411601 atacgataat tcctttcaaa taacaaccct ctatttcgag aggccgtttt ttaaatagac 3411661 aaagcatctt aattggcaat ctgacatacg atggtttgaa cccctgtatt tttggggaaa 3411721 atgggaaaaa gagacgactt tgcatatcag gccagctttt tgtttgacct ttattgacca 3411781 aaaatgtatc atgtaactac atacttacct aaaaggtgaa ggaggagcat tatgaattta 3411841 atacctacag tcattgaaca aacgaaccgc ggggaaagag cgtatgacat ttattctcgt 3411901 ctattaaagg atcgtatcat catgcttgga tctgcgattg atgacaacgt tgcgaactcc 3411961 atcgtgtcac agcttttatt cttagcagca gaagaccctg aaaaagaaat ttctctttac 3412021 atcaacagcc cgggcggctc tattacagcc ggtatggcga tctatgatac catgcagttt 3412081 attaagccga aggtatctac aatttgtatc ggtatggctg cgtcaatggg cgcgttcctg 3412141 cttgcagccg gcgaaaaagg caaacgctat gcgcttccaa acagtgaagt catgattcac 3412201 cagcctcttg gcggtgcgca aggtcaagcg acagaaattg aaattgctgc gaaacgcatt 3412261 ctcttgcttc gcgacaaatt aaacaaagtc ctagctgaac gtactggcca gccgcttgaa 3412321 gtgatcgaac gcgacacaga ccgtgataac ttcaagtctg ctgaagaagc gcttgaatac 3412381 ggcctgattg acaaaatttt gactcacaca gaagacaaaa agtaataaca caacctgcaa 3412441 gagctgcgtc tcttgcaggt ttttttcatt tcaaggaatt gactccctta ttctatactg 3412501 ctcccattcc tcatgtaaca gctcaagcgt caaatcactc gtctgcctca caaccagatc 3412561 agcaccaagc atcggctgtc cttgaccgac accaaccgca aacatccccg cagatttgat 3412621 tgcagaaatg cctgcttctg cgtcttctat tgccgcgcaa tcagcagggg aaacatcgag 3412681 catcgctgca gctgttaaaa agatgtcagg atcaggcttc cccttcgcaa gagtcgtcgg 3412741 atcaacaatg gcatgaaaat catcgataat tgccaagcgt cttaaaatct taggagcatt 3412801 gcgacttgaa gatgctaacc cgatttttat attttcgttt ttcaattgac atagaagcct 3412861 gccaatcccc ggtaaaagat cttccggcgt caatttgctg atcagcattt gataatcgcg 3412921 atttttccga tgcataagct cttgtttctc cgcatttgta tactttgttt ccgccccgcc 3412981 aaagatcaat atgctttcaa gtgactcttc tctgctgatt ccttttagcc tttcattcat 3413041 gtctctgtca aaagggatat cgatttgttc tgcgatgtgc ttccaagcga gaaaatgata 3413101 ttcagcagta tctgttatca ctccgtctaa atcaaaaatg accgctttca tatactaatg 3413161 cccatcacag cttcataagg tttgaggcta atactcttta agtcagcccg ctcctgcgga 3413221 tagtttgaaa ttagcacttt ccaacgctca tgaatcagtt ctggaggcgc ttcgaacaga 3413281 gccttttctt ccgataaatt cacaacgaca agaagctttt cccctcgata ttctcgaagg 3413341 taagaaaaga cctgcggatc attctcctgc aacagctgat aatcgccata tatcataatc 3413401 ttatattgct ttcgtaattg aatgagcttc tgatagtaaa agaaaatcga atcttgatct 3413461 tccaaagact ctttcacatt gatatcttga tagcgggaat ttaccggtat ccacgggtct 3413521 ccggctgtga atcccgcatg ttttccggca tcccactgca tcggtgttct cgcatgatcc 3413581 cttcctttta tcatcacggc tttgacaaac tctttttctg acatcgtttt gttttcgacg 3413641 actagttcac gatatgcatt ctttatttca agatcatcat acatctccag cggcatatcg 3413701 ctgttgacca tgccgatttc ttctccctgg taaataaacg gcgttccttt catgccgtgc 3413761 agaaccgttg caaatgcctt cgcacattcc ttacgcagtt tcctgtcatt gccccagcgg 3413821 gaaataaccc tcggctggtc atggttctca aaataaaggg tattccagcc gacattcatt 3413881 aacccggtct gccaccttgt catcgtcttt tttaaagcaa tcaaatcaaa cggcttgatc 3413941 tgccatttcc catttggcga gttttgttct ttatcaatat ccatatgttc aaatgtaaag 3414001 atcatattca gctcttgcct gcttgcatct gtgtactttt tcgcctcttc aatatcagag 3414061 ccgtttgcct ctccgactgt catgcagtcg taatgagaaa gcacttccct gttcatctct 3414121 tgaataaact catgaagacg tgggccgtta gagtgataac ggccgacaat atagctgcgg 3414181 ctgtgatccg tttcgtagtc cggaaaatcg gtgtatttag aaatagagcc aatcacatcc 3414241 atccgccagc cgtcaacgcc tctatccatc cagaatctca ttacatcata aacttcccgg 3414301 cgaacggctt cgttttccca atttaaatca ggctgttttt tcgaaaagta gtgcaaataa 3414361 tactgccctg ttccttcatc gtatgtccac gctgagcctg aaaagatcga tccccaatta 3414421 ttcggctctg agccgtccgg tttaggatct ttccaaagat aataatcccg gtaaggattg 3414481 tccttcgact tgcggctttc agcaaaccaa gcatgctcat ctgatgtgtg gttcacgacc 3414541 aaatccatga cgattttcat tccgcgttta tggacttcat caatcagctg aaacatatct 3414601 tcatttgtcc caaacttttc gtacatgttt ttgtaatcgc tgatatcata tccgttgtca 3414661 tcctgcgggg aatcaaatac cggggagagc cagatgacat ccgccccgag gtttttgatg 3414721 taatccagct tttgaatcac accttgcaaa tctccgaatc catctccatt ggcatcataa 3414781 aaactgcgcg ggtaaatttg ataaacgaca gcttctttcc accattcact cattaggcgt 3414841 tctcctttca catcgtccct gtaggacaac cggttcctca taaacgttca tgtgcagcgg 3414901 ctcgcctttt acaagctcaa aaataacgcg cttttcgtca accgtcacat tgattaatcg 3414961 atttcgataa ttgatgttga atgaatattc gtcccattct ttcggcaaaa acggagcaaa 3415021 tgacagcgtc tcattcgcgg tgcgcatgcc tgcaaagcca tgaacgattg ccagccagct 3415081 acccgtcatt gaagtaatat gcaagccttc ttccgtatca tgattgtaat tatcaagatc 3415141 aagccttgct gtgcgcttat ataattcgag cgctttcttt tccagcttga gttcggctgc 3415201 gagaatcgca tggacagagg gcgataggct tgattcatga acagtcatcg gctcataaaa 3415261 ttcaaaattt cgccgttttt cttccattgt aaaacggtca ttaaaaagat aaatgccttg 3415321 gagaacatct gcctgcttaa taaaattgga gcggagaatc ttgtcccatg accaattctg 3415381 gtaaagaggc cgttccgctg gatctaattc gtcaactgtt tgcaggtctt tgtccaagaa 3415441 cgtgtcatgc tgaacgaaaa tttgcagttc ttcactaaat ggatagtaca tgtgctggat 3415501 gatttctctc cagacttcca attctacttc ctgcacatcc agatggcggc gtttctccgc 3415561 tgagatactt tcgagacttt gtagagtata ctccaacgtc caagccgcaa tgacattcgt 3415621 ataccaattg ttgttaacgt tgttttcgta ttcattcggc cctgtgacgc catggatcat 3415681 atacttattt tttcgtttcg agaagtgaac acggtcggcc caaaatctgc tgactgccac 3415741 aagtacgtct atcccgtatt cttccatata gttacggtcg cctgtataat tgatataatt 3415801 gtagatcgca taacagatcg cgccattgcg gtgaatttct tcaaaggtga tttcccattc 3415861 gttgtggcat tcatcacctg tgaacgtcac catcggataa agtgccccct tcatccccaa 3415921 ttttgcagcg tttcgtttgg cagcctccaa ctgatgatag cgatacaaaa gcaggttttt 3415981 cgtcacctcc ggctcggctg tcgccaaata catcggaacg gcgtacgcct cagtatccca 3416041 atatgcggca cctccatatt tctcgccagt aaatcctttc ggcccgatat tcaaacgggc 3416101 atcgcccccg taatatgtcg agaataactg aaagatattg tagcggattc cttgttgaag 3416161 ctcctcatct cctttaatct caatgtccgc ttttgcccat ctttccttcc atcgatcagt 3416221 gtgcctccgt tttgcatctt catagccgtt ctctaccaca tccgccaaaa gctccttggc 3416281 tttcgataaa agctcttcct cccgaaaatc acgggaagtc gtgacaatca caaacttttt 3416341 caatgatgcc ttcgtttgat aactgtagcg attctcgaca tacatttcag tcgttttaaa 3416401 gctttcatgg acaaaaccct ccgtctcgtt tgccattgcg gctaataccg tgaagcgcgg 3416461 tgttccaaat ggattttcga tcgtttttgc cgctaaatgg ccgctgtgag aatcagcacc 3416521 tttcgcttcc tcctgccaaa actgttcttg gtagttagaa tcttcatttg ccacatttcc 3416581 atccaggtaa ggaacaagcg taatgacagc atctcccgtc aagcactccg cttcataatg 3416641 aatcgcacag agttctttta cagcaaggct aagaaaccgc tctgacctga ttctgacggt 3416701 tttatcttga atgcggacaa cagcgcttcg ccgcagaatc ccctctttca tattgagttc 3416761 tacctcaaat aattcgattg ggttttgatg gagatcgatt ttttcaccgt caacatatag 3416821 gcctatgccc ataaagttca tcgcattgat cacttttccg aaatattctg gatacccgtt 3416881 tttccaccag cctactcgcg ttttgtcggg gaaccacacg cctgcaatat atgtgccttg 3416941 gtgactgtcg cctgaatagc cttcttcaaa attccctctg acccccatat agccattggc 3417001 aagagacgtc aggctttcca gcagccgtgt atgctcctta ttaaatgtat ttgttttgat 3417061 tttccattca tcaatctcaa ataaccgctg atttatcatc atttcctccc gaatgtaagt 3417121 ttccattatc acggcgggtt ttggtcaaat atctaaatgc aaaagagatc atcaaagtaa 3417181 cgccacacga atggatcatc aatacagtaa tcaaatcaaa atgaaccatg ccgatagcag 3417241 ctgccgcaaa tgccggcagt gctgatgcgc aaatcgctat agaggccgct tccttgaatg 3417301 atgcaataga gaccatgttt gatatttttg tgatccagag gccacctgca agaacaaacg 3417361 ttaacaaaag ctggatcata gaaaccaccg tatatgccag catcatgatc atcggcttat 3417421 actgtgccaa ccacaatgta tcgatcaaga cctctacatc atggacgttt ggtttctcga 3417481 gcttaacgtc cattttcgca tagccaacag aaaaccccgt ttcgttttga tcggtgatca 3417541 ccagttgatc aggttgaaat atgatggcgt tttcaaatcc agttactttc aatcgcccat 3417601 tttcaccgct tgtctcatat tcatgcttca tatcgactgc catcacattc tgcccatctt 3417661 caatcctctc agagctcttc ccgcctgtta gttttccgtt cctgatttga aaaccctgca 3417721 attgatcagc aaattgatca ttaactcctt gaatcgctga cggcatgaaa gatgaaacgc 3417781 tgaagcgatc cattttcaca aacgaaaccg ctaacggcgc cattaagcag gccgttaaaa 3417841 acagaaagag aaaagagagc tgcagccagc tgaaggtatt cccatagcgg caaacacctg 3417901 atggggatgc agccgccttc aggcagcgga tgataaagct tttattctcc agattcttca 3417961 ttggcattac ccctttgttc cgccggctgt caaaccggac acaaagttct tttggagaaa 3418021 aaagaataga acgcatatcg gcagtgcggc tagtatggca ccggctgcaa atagagctac 3418081 tttttgctgc tgcggattag aaataaagga ttgtaatcct acagcgatgg tcagcctttc 3418141 cggtgagcga agcagaaatt tcgtcagcaa atagtcgcca aacggtgcca taaacgccca 3418201 aagcgcttgt accgcgagca ttggcttaac aagcggtaga acaattgaag cgaaaatcct 3418261 cagatgtccc gctccgtcaa ttcgcgcggc ttcatcaatt tctctcggca cagtatcaaa 3418321 ataacctttc atcagccacg tgttcatcgg aattccgccg ccgatataga tcgctgttaa 3418381 aaaccagtat tgatcgagtg cgcctattag catcgccaag acataaaaag cagtcagcgc 3418441 cgccattgtc ggcaccattt gaatgattaa aaagaatatc aggctctttt ttctgcctgc 3418501 aaaccgatag cggctgtacg agtacccggc aagtgtcaca atcgtaacct gcaaaaccat 3418561 gaccgatagc gcgatgacaa gtgtattgct gtaccaattg agataaagcg tttcgtcaaa 3418621 tagccgctta aaatgatcca atgtccaaga acccgaaaaa tcgagctgaa aagccgccga 3418681 attccccaca cggaaggctg atgatgccgt aatcagcaac ggatatataa tgacaatact 3418741 taaaagcgtc aaaaataaat acgtacagat tttattaagc attctggcag tgctcgcgtt 3418801 cacctacata acctcctcat tgccaaaagc attcgatttt ttgaaagcaa tcagtgaaat 3418861 tccaatgaca atgaaagaaa ttaacagtgt cacagccgcc gcaacggaat attggggtga 3418921 tgtgcctgtt gtcagtttat aaatccacga aattaagata tcggtcgatc cggccccggc 3418981 tcccgcactg cctggccctc cctcattaaa taaatagatg atcgagaaat tattgaaatt 3419041 aaacgtatac tgagtaatca tcacgggtgc tgtggcaaat aaaatcatcg ggaatgtaat 3419101 atgccgaaaa cgctgaataa aagtggcccc gtcaatcttt gccgcttcat acaattcacc 3419161 tggaatcgcc tgaagcactc ccgttaccat gacatatata tatggaaagc cgagccacgt 3419221 ttgaatcata atgagggctg tctttgtcca gaaaggatcg gtcttccacg cgatcgcagg 3419281 cagctcgaca aacggcaggt gattgaataa tggtatcacc tgtgcattca ccgctcctat 3419341 gctgtcgtta aacatgttgg aaaaactcat gattgtaata aacgccggaa cagcccatgg 3419401 aaataagaaa atcattcgaa atatccgctt gccttttata aaatcctgat tgacgaaaag 3419461 tgccgtcaca atacctaaaa tgatttgcag cgttgttgca cagattgtcc agataaccgt 3419521 ccagcccagt acattcacaa atgtttcacg ataggagcca aggaaaaaaa tatttaagaa 3419581 atttttaaac ccgacccagt caatcagacg attaggcgga atatgataaa aatcatagtt 3419641 tgttaatgca acaaacagag tcaccaaaac cggaaaaata atcacaaaca ccatcatgat 3419701 atatgccggc agtgtaaata gatacggaaa acctttatcg cccgcatgac agatcatatc 3419761 cttggctgtt gtattgactt ccaaacccgc cgctttcata gcggcggtct tacgtgaatc 3419821 atgaatatta aagatataga acatgaggaa aatcattgtc acgatcaatt gcagcgtgcc 3419881 ttcaatcagc ataaacagcg agtgatcttc accgggaaca cttcccaatg tcatcaatcc 3419941 ggttagcgcc tgtataccga aaacgcataa ttcaaaagca aacaagcctg tgatggcaag 3420001 aaataagagc ccctttgaca actgctgatt cgcaatctgc ccaagtcctg gaatgatcga 3420061 taaaagccct gcctttcgtt tttgctttgt aagtgtgtga tgtttattca tttttccgcc 3420121 ctctattctt ccggacgcta tcccgccgtt ttatttcaca tacttttctt taatattttc 3420181 ctttatgacg tttacagcat cattcgctga tgtttgtgtc gatttttttc ctgaagctgc 3420241 atcaaaaatt aaactttccg ctcctgtcca tacttcagcc atttccggaa tatttggagt 3420301 cggcgttgct gtttcatatt gtttaatcac agctgacgtc agttcattct tttgctcatc 3420361 ggctttcttc cttgcagccg tgttggccgg aacttcgttt gtatcctcat aaaaagcgta 3420421 agcattggca tcatttgcag catactcaag ccatttttca gccagctcgg gctcttttgt 3420481 atatttcgag gcaacccagc ccttcccgcc agcaaaaggg gcgtattctt ctccatttgg 3420541 caatgtcgga atgggagccg ctccgtagtt caatttagcc tctttatagt tggcagctga 3420601 ccaaggaccg ccaatgatcg cagccgcttt gccttctaaa aacatctgct gaataaagtc 3420661 gtctgcgctt gaattgtctt gcattccttt cggccaatat gtctcaaacc atttctccgc 3420721 atatttcacc gcttctacag cccctttatt gttcaggccg atgtccccgg aatctgtgcc 3420781 gttttttcca aacacatatc cgccgtatcc agccaataag ccgtacgaca tataaaagtc 3420841 agtccatttt gctaaaaatc cggttgattt tcctttttcc gaagcaaacg cgaatcgagg 3420901 atcttccgtt aacttttcaa ggtctttaaa tgtttttggc gctgttttta aaagatcttt 3420961 gttgtaatac aaaataagtg tctcaatgac tagcggcatt ccgtacactt tgccgtcaac 3421021 tgtcacctgc tgcatttctt tatcaccaaa gctttttgtg ttagatggct taatatcaag 3421081 taaatgtcct tgttgtccca aaccgccgat ccggtcatat gcagcaagca taacatcagg 3421141 cgcattaccc gccgggccat caagaggaag cgcttctaac tgttcgaaca tttgcttttc 3421201 aacaattttt actgtgacat cattttcttt ttcgaacttt gtttttatgc tttcaatgta 3421261 ttctttatac gtttcttcga cagacacagt cagcaccttt ttgccatcag agcttgctgg 3421321 attttttgaa cttgagcagg cggcaaggcc gattgccagg aatgatgccg ccaatatggc 3421381 gaaccccttt tttaaaagaa ccatctcttt tcctccttct atttacgaaa ctataacaat 3421441 tgtattgtcc tatagaaagc ggttacaaca actttcgatt tgttaccgat aacagaatgt 3421501 tatacagggg cggcagcact caaaatcaaa aattctcccg gctgaacggc aatgacatcg 3421561 tgatgctgta gcggctgctc tgtccatgca tcacagattt tcttattcct atcaatattc 3421621 aactctcgta aactgacgtg ttgaaccaca ttcccttgat taaagaaata aatcagtatt 3421681 ttttcatcaa gagtccgcga aaagctaatg aaatcatttt tgtcgtccag cagattccac 3421741 tcaagatgtc cttcagtcaa taaagtgttt tcctgcttgc gtaaagcaat taaccgtttc 3421801 ataaattgca gcatgtcttg gttttgcttc tctttttccc aaaccataca tttccggcat 3421861 aatggatcat tttcgccgtt cagcccgatt tccgttccgt aataaatgca tggtgagcct 3421921 gtctgggcaa acataaaggc cagcaacgcg cgtgctttct tctcatcatt gcggcatctg 3421981 gtcaaaaggc gctttgtatc atggctatcc agtaaattaa acatcacctc attggcctgc 3422041 ttcattccat tcatcaaatg tgcattgaca cggtgagcca tacgtgaagc tgagatcgtc 3422101 tggtcagcaa agtattcaat cataggctct gtaaaagggt aattcatcgc cgcatgaaat 3422161 tcatcccctc taagccaggg ttcggcagaa tgccagatct cacctaaaat ataaacatca 3422221 ggcttttcag tagatacagc ctgcctaaat gtcttccaaa aaacgtgatc cacttcattt 3422281 gcgacatcca aacgccagcc gtcaatgtca aattcgcgaa tccagtacaa agcaatatca 3422341 agcaaatatt tctgcacctc gggattagcc gtgtttagct tcggcatatc agctgtaaaa 3422401 gcaaatctgt cataattgtc gtctgtgacg ggaaaagagt gaatatggaa ccagtcctta 3422461 tagcgggatt gatctccgtt tttgacgaca tcctgccatt gcggagacgc gcttcctata 3422521 tggttaaaaa ccgcatcaag cataattctc atcccccgct gatgcagctg gctgaccaat 3422581 gtacgaaaaa gctcaggatc cccgaaatgc ggatcaatag aaaagtaatc cagcgtgtcg 3422641 tatttatgat tagaaggcgc ggaaaagatc ggtgtcagat aaatgccgtt cacccctaaa 3422701 tcctctaaat aatcaagctt gtcaacaatt ccttgtaaat cccctccaaa aaaatcattg 3422761 acgtccgggt ccttgctccc ccacggcaat gcattcttcg gtgacaagtc ttctcttcca 3422821 tttgcaaaac gctccggaaa aatttgatac caaaccgttg acttgaccca ttcaggcgct 3422881 tgaaatgtat cagcctcgtg aacaaacgga aatttaaagt aataatgaat cgtttccagt 3422941 gttttttcgt tataagggca tacacccgaa cttccgaaaa agatgtcttc atgatcgtct 3423001 gttacaacaa acgcatattg taaacgccta aatggcggca ccacttcagc aaaccaatag 3423061 tcatgcattt ctgtagcagc aattttcctc atcggctgct cgtttgccga ccatttgccg 3423121 tcgttgtact catagggatc accccaaatg aatcgaatgt gatctgcatc accttttttc 3423181 gtccgaatct tgatatgcac agtccgccca tcataagaat aagcatctgt gctgaatggc 3423241 tggtgatgaa tcgctgcata ttccatcatg tttccccctt tgatttccgt tttattgaag 3423301 ccggctcata gtttgaaagt atcatgatga aattgtggga acaatccttt tcaccctgtt 3423361 accgataaca gaataaggcg cttacagcgt tgattctcgt acaattaact ctggttcaaa 3423421 aaatagactt ccttgtgcag cgccgtcttc attcattttt ttcagcaaca ttttcgcaca 3423481 ggcttccccc atttcaacaa caggctgtct gaccgtagtc aagcgcggcg aggagatgcg 3423541 atcaagaaac acaccgtcat tcccggtaac cgcaacgtct tctggaattc gctttccaag 3423601 ggattgcgcc gcacgaatga cgccgagcgc gattcgatca gatgcgcaga caaatgcggc 3423661 ctgattgtcc atggatttca gcagttctct tgcaaggcat tcacttttct tagaactgtt 3423721 gtcgatccga aacatattcg attttttaaa gcttttattc atcgcccgta tatacccctg 3423781 ttctcttgca cgttcgaaag gctcatctaa atcaatgcca aaaaagacaa cttcccgctc 3423841 ccccagcccc ataacatggc gggttgccat aaaagtgcct ttctcgttat tcacatcgat 3423901 aaagtcatag cccatttcat tttgtccaaa tacgacgagc ggcttctcaa aagcttttat 3423961 tacaccttca aaatcgttct ttctcaagcc ggtggcaata atgccgtcac attggccaat 3424021 attaagagaa tttcttgtca caagctggag agcatagtga ttgcgatcca gctccctgct 3424081 gattcctgtc agcaggttca tgtaatatgg ttctgtcgta tccatttcct caagtatcaa 3424141 tagtttcaca acctgtgttc tgttttgcac gagcgctctc gccgcataat tagggatgta 3424201 attcagctct ttcatcgcag aatgaacaag ctttttcaat tcatccgtca ccgtctcagg 3424261 gtgattgatc actcgtgata ccgtcatttt cgaaacattt gcttttttcg ccacatctga 3424321 caatgttgcc attttcatcc cctccttatc tgtgcttatt atccaaacta gtgataaagt 3424381 cctctattac tgctaaatat acgatgcagg ccaaagagaa ataaaaaaga gatttccctt 3424441 aaggaaacct cactttgtta aaaacactcg atttttcatg gattcatacg ctaggtggca 3424501 gactcattct ctccacttcc atcagaaaat ctctttttta aatttctgtc cacttttttt 3424561 ctaaaatcgg ataagaataa ttttgcattt gctcaattaa ctcatccggc cgtgacgagc 3424621 tgtgaatcag ttttaggtgc gattcgttag aaaacccttc ttgaatgctg tatttcacca 3424681 ttttcatcat tggttcaaaa tatccgttta cattgtacag tccaattggc ttttggtgga 3424741 tgccgatctg tgcccagcac agcacttcaa ataattcttc atatgtaccg aagccgcccg 3424801 gcatcgagat aaagccgtcc gccagctcgc tcattttagc ctttcgttca tgcatcccgt 3424861 ttacttcaat cagctcagtc agattctgat ggacaacctc cccgctgaac aaaccgctcg 3424921 gcatgacccc gattgcagtt ccgccgtttt ccataatcgc gtcagcaatc gtgcccatca 3424981 agcctacgcg ggagccccca tagacaaggc cgattccctg ctcagccata tacacgccaa 3425041 gctctgccgc ttttctttta tacgcttcat ttcccccagg gtttgatccc gcaaatacac 3425101 aaatggtttt catcttgtca tctccgcatc tatatatcgt gttaaacatt caaaaacaca 3425161 ctatatattg tcccatcttc atgtgataat atcaatatga aatacataaa gaatgcagga 3425221 gtgatgaggt tgcagctggc tgatgcagaa aaatggatga aagagtttta cgaaaaaaga 3425281 ggctggacag aatacggacc ttttattcgc gtcggctttt taatggagga agccggagaa 3425341 ctggcccggg ctgtcagggc gtatgaaatc ggcagagacc ggccggatga gaaagaatcg 3425401 tcacgcgctg agcaaaaaca agaattgatt gaagaaatgg gagatgtcat cggaaatatc 3425461 gccattcttg ctgatatgta tggtgtctct ttagaagacg tcatgaaggc ccaccaagaa 3425521 aaactgacaa aacgatttga gcatgcataa aaaagcggcc gcgatggccg ctttttttaa 3425581 cctgtgattt catcatggtg atcaaagaaa tgctgctttc ctattttgtg aaaaaggcct 3425641 gttttatgca gtagctcctt cggctgcgat tgcaatccta caatcatcag ctttccattg 3425701 tggcgtttaa ttcgattcat aatgttccca agcaccgctt cagctgacgt atccatatag 3425761 tgcaccttat tcatgagcag aataagggtt ttcggttttt tctgtacatg ctccagcaat 3425821 gacgattcaa gggaatcaat tgatccgaaa aacagcggcc cttctatggc atacatgctg 3425881 acagatggat cttctctctt cgccagaaca ggatgcgttt cctgattgtg gatgcgggtc 3425941 gcttcgctca ttcttctgat aaagaacacg aatgcaagca gcaatccggt tgccacaccg 3426001 atgattaagt caaacagaac cgtaagggcg aaggtcgccg ccaaaataaa ggaatcagca 3426061 tttttcagtc tcagcatgtt tgcgacttcc ttgcgctcac tcatattcca tgcgaccacc 3426121 atgagaatcg gtgccatact ggcgagcggc acatgggacg cataaggcgc aaatacaagc 3426181 aggacaagga gaacgactac gccgtgaacg acgccggaaa ctggggaaac cgctccgttt 3426241 tttatattgg tcgccgttct cgcaatcgct cctgtagccg ggattccgcc aaacaggggc 3426301 gctgccatat tcgcaatccc ctggccgaca agctccttgt tgctgtcatg ctttgagccc 3426361 ttcatgttat cagcgaccat tgcggacaaa atcgactcaa gtcctccaag aagcgcgatg 3426421 acaagcgcag ccggaaacag cataaccatt ttatccaaag taagctcagg aaactgaaat 3426481 tccggcaaat ggcgggggat ttctccataa gttgacccga tcgttgccat gcggtcaggg 3426541 aaaaagacaa ccgcgaccac tgtggaaata agaagcgcca acaaagcgcc cggcacttta 3426601 ggcatcacct tggcggatac aagcaaaatg acgagcccga tcacagctgt caaaatggca 3426661 tacacgttaa aggtgccgag ctgctgcaca atttcaaaca tgttgtgatg aaagttctca 3426721 tgtttttcaa catttctcaa tccgagaaaa ttagcgattt gttccgtaaa gatcagcacg 3426781 gcaattccgg ctgtaaaacc gacgataacg ggtttgggca cgaatttcat tatttttccg 3426841 agcttaaaca gcccaaacag taccagcatc actcctgcca taaaccccgc aatcagcaga 3426901 ttttccaagc cgtactgcat gataatgccg aataaaatcg ggacaaaggc gcccgtcgga 3426961 ccgccaatct gatattttga tcctccaaac aaagaaatac aaatccctgc tataacaaca 3427021 gtgtatagcc catattcagg ctcgactccc gaggcaatgg caaacgccat tcctaaagga 3427081 attgccacga cacctactac gatacctgca atcaagtctt tctgaaattt ctgcaaattg 3427141 tatcccttga atctccctga gaatcgcata ttttgttata acctccctta tgagtgattg 3427201 tttataagct cagtttcata accgttaatg accacatcaa gttttcctgt ttcagggtga 3427261 atgacaagcc cgtgaaccgg cacttttttc ggaagcagcg gatggttctt aatcatgttc 3427321 acactgtggg aaacgctttc ttccacgctg tgaaaaccag tcagccacgt tttcaaatcg 3427381 agtccggcac tcgtcagcaa attcaggcag ctatcctcca ccccgcgttc ctttgctttc 3427441 tcaagaatcg aggacgcatt cagccctgac attccgcatt catgatggcc gacaatgcat 3427501 acctcttcag cctgcaattc ataaatcgcg accagtatgc ttcgcatcac gcttccaaat 3427561 gggtgagaaa cgatggctcc cgcgtttttt acaattttag catcaccgtt tttaagcccc 3427621 attgcttgcg gaagaagttc tgtaagcctt gtatccatac aggtgacaat gacgagcttt 3427681 ttcgaaggaa actttgtcgt tttgtacggt tcatacttct tctcactgac aaaccgctga 3427741 ttgtgttcca aaattgatgt taaagaaacc atttgattca tctcccatcc atatgatttt 3427801 gcaagccttc ttacccagct tacagtaagg aattatagca taggaataag ccaagaaaag 3427861 gttttcaaaa aaagacacta taattggact gtagaatcaa aacataaaca tttatatctt 3427921 tcaaagataa taaaatttat atttaatgca tcctataatc cggctgcagt tcgtatatcg 3427981 atgatttgtc tgacaaaaaa tatgggtgaa ttctgataat taaaaaactt ttttaagcag 3428041 atttagctgt tcgatcttca ttttaagttc aaaagaacca gaaattaaaa aaacgcagct 3428101 atatttttaa catctattta ttttcgatat aatgaattag acaacagcca taaaggggga 3428161 gccttgttga aaccatttgt atttatcaca aaaccgattc ctgaagagat tgaagcattc 3428221 atcggtgaac attgccgtta tgaagtatgg caggaggata cgcttccgag tgacgtgcta 3428281 tttgaaaaat taaaagaagc ggaggggctt ttaacatcag ggacgtccgg accgtcaatc 3428341 aatcgtgagt tgctggaaca cgcgcctaag ctcaaagtgg tcagcaacca atcagtaggc 3428401 tacgataact tcgatataga agcaatgaaa gaaagaggag tcgtcgggac tcatacacct 3428461 tatacactgg atgacacagt tgcagatctg gctttttcac tgattctgtc ttccgccaga 3428521 cgtgttgccg aactggaccg ttttgtcaga gcaggaaaat ggggaaccgt ggaagaggaa 3428581 gcgcttttcg gaattgatgt tcatcatcaa acgttaggca ttatcggcat gggcagaatt 3428641 ggagaacaag cagcgagacg cgccaaattt ggttttgata tggaagtgct ttatcataac 3428701 cgacatcgca aacaagaaac agaagacagc atcggcgtta agtatgcaga gcttgataca 3428761 ttgctggagc aatctgattt tattcttctc attacgccgc tgactgatga aacctatcac 3428821 atgataggag aacgcgaatt taagttgatg aagaattcag caattttcgt caatatttcc 3428881 cggggaaaga cagttgatga aaaagcactg attcgcgctc ttcaggaagg ctggatcagg 3428941 ggagccggct tagatgtata cgaaaaagag cctgtcaccc aagataatcc gctcctgcag 3429001 ctggataatg tcacgctgct tcctcatatc ggttcagcaa cagctaaagt gcgcttcaac 3429061 atgtgcaaac aggccgccga aaatatgctc gcagcgatcc aagggcaaac accgaaaaat 3429121 cttacaagag aatttcaata aatcaaaaat ccggtctgat aacagaccgg atttcatatt 3429181 acatacgctg aagaacagca cgcttataaa tatgacgggt gacgatataa taaagagcct 3429241 ggaatacaaa ataaatgaag atgacaatta cggcctcaag aaataaattg gaattcagca 3429301 tattacttaa cgctgcatac gcaaagcccg cgtgaatcgt acctgcgata aatgggatga 3429361 agaataaaaa tcctatttgc tttccaagga tcgagtgaat ctctttgtcc gtaaccccta 3429421 tcctctttaa cgctaacacc tgcactcccg tatcttctat ttccgtaaac atccgcaaat 3429481 acagcatgct tccttgcacg ataaaaaaca gcacgctgac aaacagacca ataaacagca 3429541 ttaatgcaac tccctgcttc acaatttgat aactaggagc acgtgtttga aaatcagatg 3429601 tatgttcttt cggcaccatg ttttcaagct tttcagagac atccaccgtc tcctgccaat 3429661 gctcaagctc ataacctacc attctcatct gttccttcag cggcacatcc tgtgacagac 3429721 tgtcaaagct cttttcgctg acaaccaata aacggctgac tccatcgaca gacatcaata 3429781 tccctttgtt ttgctgcttt ttcatgacat aggaaagggt ttttcctgac ttcatatgaa 3429841 atgctgctgt ttccccttct ccaaatgtgt ctttcaccat catttgaaaa gaaacattaa 3429901 taaatgcttc attttcttgt aaatgaataa ctgggaaccc tttttccttt gcgacttgat 3429961 tatagacttt ttctgaaatc agcaaagctt cagcttccat cttcttattt ccatacggca 3430021 agtctgactg aaaagtgaca ggaatccctg tggcatccac cttatacgtg ataacagcat 3430081 gagctttttt caatgtattc tcagccgtct caggcttcat gacctgaaag cgggaagcat 3430141 ccttttccac ccaggaaaca gactgaggaa tgctttgctc ctcctgcctt tgtaaatcgg 3430201 aataaaacat atagatgaca cctgtagctg ttagtatgac cgctgtaatg acagaggtta 3430261 aaaacagcat gcgtgcatga tccttcagcc tgaatatcat gttggaacgc acaatgatat 3430321 ttgtgccttt gtagaagctg tgtttctttc ggtacagcat gcggaaaaat gccacactgc 3430381 tttgggtaaa aaagaaatac gtgccaatta acactaaaat caaaattgga aaaacccgaa 3430441 acatcatgtc aattgcattg gctgttgcag atagataata accgctgcca agacatagca 3430501 aagacaatac agtgagccat ttcgaataaa ctggcaaact tttcggcttt ttggctgatt 3430561 taatcagttc aatgatttcc agcttccgaa tccgtcccag tgataaaatg agcagcgtct 3430621 gaaacaggat gagaaagccg gcaattgtca tcacaaacgc tttcggcaca atggcaaacg 3430681 aaatcggcac cttcacgctg agcatccatg tcatgatcat aaaaaacagt tttgaaaata 3430741 acaggcctgc tccaatgccg gccgcaatcg ccgcaagaga aataagtgac tgctcataat 3430801 aaatcatctt gcgaagctgc tgctttgatg tgccaaacag tgtcagcagc ccaaactctt 3430861 tctttcttgc ctgcaaaaac gctgaattgg aatatgtgat gaaaaatata caaaacacaa 3430921 tgatgacgac aagagctgcg ctcaagcatg ttttgacaag gcttcctcca tatatattgt 3430981 cttcattgac atcaggatga aaaataaatg atgtgaagac aaaaaacacc gaaacggcaa 3431041 acacacagct taaaaagtag gccacatacc gttgcagatt cccaagaatg tttttacggg 3431101 cgatagttct caaattcatg aaaatcgcct cccaacacac tcaaggtatc caatatactt 3431161 tgataaaaca cctgcctgtt tgttcctctg tgaatctctg aaaagaaacg tccgtcttta 3431221 ataaaaacaa tccgtttaca gaaacttgct gctgtggcat catgcgtaac caacaaaatc 3431281 gtcgcttcct tttcctcatt cagctgagcc agtgtgttca tcacttgctt tgccgatttt 3431341 gagtcgaggt ttcctgtcgg ttcatcggca agaatgagcg ccggattgtg aataatcgct 3431401 ctggcacaag ctgcccgctg ctgctgtccg cccgacacct catatgtgcg gtgatcgaga 3431461 atatgcttta tttgcagcgt atccgccagt tcatccaatc gagcttccat ttctctcagc 3431521 tttaccttat ccaatgcgag cggcaagaga atattttcac gaatcgtcag cgtatcaagc 3431581 agattaaaat cctgaaagac gaagccgagt tctcttctgc gaaacaaagc cagctcttgg 3431641 tcctttaacg ttttcggctg aatgccgttg atcatcatct cgccctgggt cggcttatca 3431701 atggtagcca gcaaattcaa aagcgtggtt tttccgcttc ccgacggccc cataatcccg 3431761 acaaattctc cttttgacac actgagatca aaggcgctga gcgcttggta tgatattgtt 3431821 cctttatttg aatagtatgt tttcgatagg ttcgttgttt gcaacacgtt catgttctgc 3431881 tcctcctttt tctttattat aaaaaggaag tcagcatcct cccatcgaac tttcttgcaa 3431941 ttccgctccc caatcttaca atgctgtcac attcacgagg gtgtcacttg aaaacacgat 3432001 ggtcatcaca gtgccagccc cttcttttga ttccgcatac agcttatggc cgagacggct 3432061 gcacacctgt tttgctaaat aaaggcccat tccagttgcc tctttcatgg ttcgtccgtt 3432121 ttctccggta aaaaacgcgt caaaaatccg cggcagatcc tgcggcggta tgccgattcc 3432181 ttcgtcggca accgacaagc gcgtctcatg tccctgtgtt tcaatccgga ttgtaatagg 3432241 gtctcccaca ccttgctttg aatattttaa ggcgttgaaa aggatttgct caacaacaaa 3432301 ggaaagccac ttttgatcac tggaaatctg aacggcattt ggcggcacat gtaatgttgg 3432361 aaaaaggcgc cgcttgataa actgacgttt ttcctgattg atcagtgaac gaaccatttc 3432421 tgccaaatca aaggtttgcg gctttacatc aaatgcaaat tcctccagcc gggccgtttg 3432481 cagcatcata tcaagaccgt ggcgaaatct ctcattctca tcctccagct cctctaaaaa 3432541 cgtcggaaaa gaggatgagg ttccgttttt tccttcctga atcattaagg atatgacaga 3432601 taccggtgtt ttcatatggt ggacccattg gttggtgaag gtgtaatgct gtttttgctg 3432661 attgatatat tgtgagagcc tgctttcgta ttgctgcccg agtgcgttga tcatcttcgt 3432721 ccaaagcgct tgctctcctg ttcttggctt tctggctttc aaagactgtc cgatgtcatt 3432781 cgaagaagag gcttgttctg caagcttttt aacatatgtg agaaaggaaa attgccgaac 3432841 ataatcagca gcaaaacctg cggctaaaag agtaccgggc aaaatccata tgtacatcat 3432901 attttctttg gaaggttctg cgccgctctc tacaatgctt aaatacgcaa tcagcatggc 3432961 ggaccctatc cctaataatg aaaatagaat aatggctaag cggtcgatga gataagtctt 3433021 taacattccg cttcatcctt ccgattgact tgaaattgat aaccttgtcc tctgattgtg 3433081 gaaatgcaat ctgtcagtcc tgcattctcc agttttctcc gcagccgatt gacattgacc 3433141 gttaacgtat tgtcatcgac aaaatcaacg tcatcccata acgcctccaa tagttcatca 3433201 cgagagacaa tttttttatg ctccctcaca aaaatcgaga gaagctggaa ttctttttgg 3433261 gaaaacaaaa tccggacgct gttccattcg gcctcattct gatcaggata aatcgtcagc 3433321 ccgccaagct ccactattct agattcctgc ggcaaagagg gcgaatattc accatatgtg 3433381 cggcgcagga cgcttttgat tttggccatc actacctcta gatggaacgg ctttgtgata 3433441 taatcatcgc cgccattttc aatcgccatt acctgattca gctcatcggt ccgtgccgat 3433501 ataaagataa tcggcgcatt ggaaatggta cggatttgcc tgcaccaata aaacccgtca 3433561 aaaaaaggca ggttgatatc aagcagcaca agatcaggct tcatttctgc aaattccaat 3433621 tttatatcat tcagctgttc agcaattttc acttcatatc cgtatttttg aagatgaccg 3433681 cccagcaaag aagcaatccg ctcatcatct tccacaagca aaatccgata cacgttgatc 3433741 ccccttatat gtacatcacg atgatttttc tagaagattc caaaattatt atagcatgtg 3433801 cggaatagta aatcggtctt tttctttttg ttatgataga atgataaagg taaaattttc 3433861 ataataggca ggtgtcgtga tgaagaaaat catgctgttt ctggcaatga cgtcaattct 3433921 ttcagcatgt cagcccaact ataccgggaa atacatagaa attggggata cactaactga 3433981 ctataccaaa gagtgcttta aagagaatga aattccttat aaatacgaaa agggaaaact 3434041 gtatatccca gaagacgcat ttgatacagc aatctacact tgttcataag aaaaagcttg 3434101 cagataacct gcaagctttt cacgttacaa aaaatgagta tttaatttct cttcaaatcc 3434161 tgaagggccg atgtcgcttt tttgaatgtt accgccgttt tcataaatcg taaaatggcg 3434221 ctctgacatg accatccttc cgctcggcgt cagctttgag gcaagcaggg atttgttaaa 3434281 aggagatttt tcatgagagt gaatgatgtc cttcatgtta tctaaatcac cgagatcact 3434341 ctcttcaagg gtaaaggcgt acccaatttg ccagccttct cctttgtcca tcagcagaac 3434401 atagctgccc ttttctgtct cttccttttt gattcggaat gacccgactg gtgactgtac 3434461 cgtttctccg gaaagcggta tcggctggag cgccaggttg atgccgaagc cgatatcaac 3434521 gaggtaatcg ccgttttccg cagacagcca tacagcagca tgcgtccctt ctagtgccca 3434581 tccctcttga tcgcctgcat aaaccgttcc tcgaatgagc ttcacatgaa acccggcctc 3434641 acgcaagaca aaataaagga aaccatttag atcgtagcat aggccgccgt gctgatcttt 3434701 gagcagacgt cgccatagct cttcttttgt gatcttataa ttctcttttg caagtacggc 3434761 acggttttcg aatggaaaac ggtatgccat tgctttaaga aaaaggggaa gatcgccgaa 3434821 gctgacatgg tctttctccc agccgatttt ctgaaagcag tcttttagaa agtcactcat 3434881 ttttatcacc taaacttctt cttgaacgta agcagccagc ttctccagcg cctcttgttc 3434941 atcttctccc tgggcaatca aggtaacctc agtgcctgtg cttaccgcaa ggctcatcag 3435001 ccccatgatg cttttggcgt ttactttttt cccatccttc tcaagaaaca catctgacgt 3435061 aaaccggttt gcttcttgta caaacaaagc agcaggacgt gcttgcagtc ctgtctttaa 3435121 tcgaacttcc actttctgtt gaaccataag atctcccctt ttctttacgg ttattttaaa 3435181 gtgacggttt gccctgtccg cagctgttct gcgatttcgt caagttttct cagcctgtga 3435241 ttgatccctg atttgctgat tttcccgctt gctaccattt cccctagctc tttcagcgtc 3435301 acttcctgat aatcaatccg cagctgcgca atttcccgaa gtttttcagg cagcgcctcc 3435361 aggccgattc tttcatcgat gtatttaata ttttccacct gtctcagcga tgcgccgatc 3435421 gttttgttta agttggctgt ttcacaattg acgaggcggt tgaccgaatt tctcatgtcc 3435481 cgaacgattc tgacatcctc aaatcgcaga agcgaattgt gagcgccaat tacgttcaga 3435541 aactctgtaa tcttttcagc ctcttttaaa taggtaatat agcctttttt ccgttcaagc 3435601 gttttgctgt ttaactgaaa ctcatttaac aggtcacata atgaatcgtt atgctcctta 3435661 taaagagaga agatttctaa atgatacgag gaggtttccg ggttattgac cgaacctcct 3435721 gccaaaaatg ctcctctcat ataagaacgc ttgcagcatc tctttttgac cagctctttc 3435781 gaaatacttc gttcaaacac aaaattctcc ccgagtattt ttaaatcctc taagatcgct 3435841 tttgcatttt ctgaaaaacg cacaatatag acgttattct ttttcagccg cattttcttt 3435901 ctgaccagca gctcgaccga cacatcatat tgttttttca gcaatgtata gatgcggcgg 3435961 gcaatcgccg cgttttcggt ttgaacatcg agtacgagat ggcggtttgt aaatgataaa 3436021 gctccattca tccgaatgag tgcagacagc tcggcattaa tgcagcagtc cttcacttcc 3436081 agattcgtta attctttttt tgtttctgat gcaaatgaca tatagccacc tcatttcaag 3436141 gcttcattct ttcagtaaat caacaagaag agaggccact ttatgtgtat cgtgacgtat 3436201 tacgtcattt ttatacgtta caatttgatc tctgatgact tcaagcccca tcgctttcag 3436261 ctcttcgata tcaaaatcaa caggacgcgc cgattccatt tcgtacttac gttttatttc 3436321 gtcgggaatg tcttcactgt tcactaatat cgtatcaata aaaccacagc ccatatgctg 3436381 attgagcgct ttcacatgat cagcagcggt gtaatggagc gtttcgccgg gctgagtcat 3436441 cacgttgcaa atgtatactt ttttcgccgg cgcctttatc acttcttccc cgatttttgg 3436501 gacgagcaaa ttgggaagaa tgctggtata gaggcttccc gggccgataa taatcaaatc 3436561 cgcttccctg attacgtcta ttgtttccgg cagcggatca atctgttcag gcgtgagaaa 3436621 aacacgctta atgcgctgtc cgtattctgg gatcgttgac tcgcctgaga ccacgcggcc 3436681 atcttccatc tcagcatgca aaacgacact ggcattggca gccggcaaaa cctttcctct 3436741 tacattcagc accttgctca tttctgtgac agcgtgaaaa aaatcaccgg ttatatttgt 3436801 catcgctgcc aaaatcaaat tcccgagaga atggcctgtt aagtcattcc ctttattgaa 3436861 gcggtgctga aaaagatctt caacaagcgg ctccacatcg gataaagcgg caagcacatt 3436921 tctgatgtct ccgggaggcg gaattttcag ttcattccgc agacggccag agctcccccc 3436981 atcatcggca actgttacaa tggccgtgat gtcaacgggt ttatgcttta ggccccgaag 3437041 caatacagaa agacctgtac cgccgccaaa gattgcgatt ttcggctttt gtcccatctt 3437101 atttccggct tctcttttca atgtcccggt gagtaacatg agtatagtaa tcctttttga 3437161 aataatcagc taaattctcg gctaatgtca cagagcggtg ctggccccct gtgcagccga 3437221 tcgcaatgac aacctggctt tttccttctc ttttgtaaga tggaagcata aagctcagca 3437281 gatcaattaa tttctcattg aacttttgcg tttcattcca cttcatgacg taagaggaaa 3437341 cctctttatc cttgccagtc agcggccgca tgctttcgat atagtacgga ttcggcaaaa 3437401 atctgacatc aaagacgaga tctgcatcaa ttggaatacc gtatttaaaa ccaaatgaca 3437461 tcacatttac ggtaaatgtc tctccttggt ttgtcgcaaa gtgcttcacg attttttcac 3437521 gcaaatcacg cggcttcatg tcagacgtat cgtaaatgat ttgagagcgg ccttttaatt 3437581 cctcaagcag ctctcgttct agcgcgatgc cttcaagcgg caggccagtc gctgccagcg 3437641 gatgcgagcg tctcgtttct ttatatcttg tgacgagaat ggaatccttc gcgtccagga 3437701 ataaaattcg cggtgtgatc cacggatttt cggccatttc atccagcgct tcaatcagcc 3437761 ggtcaaaaaa ttcgcggccg cgcaaatcca tcacgagcgc aactttgctc attttcgaat 3437821 ttgattcctt catcagctct aaaaacttcg gaagcaatga aggcggaaga ttatcgacgc 3437881 agaaatagcc gagatcttca aagctttgga tcgcgacagt tttccccgct cccgacattc 3437941 cagttataat gacaagctga atatcatgtg attcactaac actcatcttt ctcccccctg 3438001 acttgtcttt ctatttgatg tgctgcgggt ctaaacgata actgagcagc tcaaattccg 3438061 gtgtatacgt aaatgtgccg tgcagcagcc cttgtccctt catcataaaa tcaaggatat 3438121 ggccgtctcc aggggccata ggcaggttct gaatgtcatt gacatcgtgc cactgcagtt 3438181 tgccttcctc tgattctgat acattttgtc ctgtatatga atcagcgaca aacgtaaaca 3438241 tcatccactc ggagacaatg tggtcaccgt ctttaataat aaaggtaaaa acgcctttta 3438301 attgaggatt tatgatatag ataccagtct cttctctgta ctctctgatg acggagtctc 3438361 tgactgattc tccgctctcc atcttgcctc ccggcgcgac ccaccatccg cgtctcggct 3438421 tttgaagcag aagaactttg tcatccgtct gaagcacaca atttgtcact ctttgcaagt 3438481 acgtcaccta accttcgtcc tgtcatcgtc tctttattat accgcttcaa gatgcctccc 3438541 acaatgaaga gacattgaca atcttttctt ctattttaca gcatattcat tccttaattc 3438601 agatgatttt gctgtaactg gaattctctt ttatttatgg acaaaaaaag gacacggata 3438661 actggagaat ccgtgccaaa aaagtgtatt cattataaaa agggggtcaa ttactttatt 3438721 aatcataacc gaaaagcatt acacatgtgt tacagcggaa ttaaaaccca gtaacgtaat 3438781 gtgaaactcg tatgacagcc ctttttattt taaggttttc agcgtttctt ggagctcttc 3438841 gacataatgt tgtacgcttt gtgccgcaat gcttccgtct cctgtagccg ttacgatttg 3438901 gcgcagtgat ttttcgcgga tgtctccggc agcgaaaatc ccttcaacct tagtttccat 3438961 gcggtcgttt gtttcgatat agccttcttc attcgtaatg cccaggtttt caaacggttt 3439021 agacagagga agcatgccga tgtaaatgaa tacgccgtct gttttgaatt cactttcttc 3439081 accggttacc gtatcgacaa gcgttacgtt accgactttg ccgttttcct catgaatttc 3439141 cttcacagtt ttgttccata ggaagtcaac tttttcatta tcaaatgctc tcgcttgaag 3439201 aatactttga gcacggagtt tatcacgtct gtgaacaatc gttacttttg aagcgaaacg 3439261 agtcagatat acgccttctt caaccgcgga atctccgccg ccaacaacga caagttcttt 3439321 gcctttaaag aaagcgccgt cacatactgc acaataagat acaccgcgtc cgcccaattc 3439381 tttttcgcca ggcacgccga tttttttata ttccgcacct gcagcaatga tgacagcacg 3439441 ggctttatat tcctttgaac cagctttgac tactttgtac tctttgccgt caatgacctc 3439501 tttaatatcg ccataagcgt attcagcgcc gaattttttc gcgtgttcaa acattttgtt 3439561 agaaagctca ggcccaagga tactttcgaa tccaggatag ttttctacat cttccgtatt 3439621 ggccatttgt ccgccaggaa ttcctctttc aatcattaat gtcgataaat tcgctcttga 3439681 tgtgtataca gcggccgtca tcccagcagg gcccgcgccg attataatca cgtcataaat 3439741 tttttcttct gacacactat tcactcctta aaccatcttt tcaagtttgg gctctttctt 3439801 ataagataag aatccccatc aaacgtattc cttacccata tcctataaaa tctcatggtg 3439861 atacgctatt tttttgctca acacgattaa atgtattcga aaagggtata tgttaataaa 3439921 gaaagagcct tctgtttata gaaggccctt gtcatattta ttattgaaca acacgtctta 3439981 caacaccttt aaatgctgct ttccagtaag gattgctcat agagtcaaca gatacgccat 3440041 gagatgtatt gtcgtttagg aaagtaccgt ttcctaagta gattcctacg tgtccatttg 3440101 ttttgtaagt gtcaaagaac acaaggtctc cgcgtttcat ttcagacgcg ctgacagctt 3440161 gtcctctgcc aactaacgta tcagttgttg ttccgcctac aggtccaagg ttaacacctg 3440221 cagaagcgta tgcccagcgt acgaatgatg agcagtcaaa aatacggttg ttgatatcag 3440281 actgagtgcg tccgccgcca aacttgtacg gagattgtcc tacaatgctt gaaccaacgc 3440341 tgatcgcgcc ttcaattccg ccagagttgc tgataacagt gccgcctgaa ttgctgtttg 3440401 agccgctgct cttcttagaa gatgagccgt ttgacgaact gtttgatgaa ccgttagaag 3440461 aattgtctga agaattgtct gaagaatcat cagatgagct tgcttttgat gattcagttg 3440521 tcgccgtttg actgtcatct gtttgtgttt catcagatgc tttttgtgct tcttcctgct 3440581 ttttgatcaa agcagccgct gcttcttgtt cttttttgat gcgtgcttgt tcagcttcag 3440641 tatttgcttt ttgatttgca agttcagacg cctctgattt taattcagaa atcgctttag 3440701 ccgttttctt ttggcttgct tttgcttcgt cgaaaagctt gtctttttca ttaagctgtt 3440761 tatcaaggtc tttttgcatt gtttctaatt tagccaaggc agcttgaact tctttcagct 3440821 tgtcattcaa atccgcttca gaatcttcga gcttcgcttt atcctgctct tgctgtttga 3440881 ttaaatcttt gtctgcgtcc acaatagatg aaaccgcagt cgcacgagag ataaagtcac 3440941 caaagcttgt tgatcctaaa agaacatcta tgtatccttg agatccgccg ctttcctgta 3441001 aagaacgaac gcgttttttc aggatttcat tgcgtttttc gatgcgtgct tcagtttctt 3441061 taatctcttt tttcagtttt ttgatttctt cttttgtttt atcgttttct tcttttttat 3441121 cttcaatctt gttgcttgta tcaagcgcct tatcgttaat gtctttcagt tctttttcaa 3441181 tctttgattg attttcctga agctcggtta attctttttc cttcgcttca atgctggaag 3441241 caacctcaga ttgcttgctt tcgatttttt gtttcttttc atctaatgtt tccgccgatg 3441301 cagttttact tgtaaatggg atcaaaaaac tgcttgtccc gatgacggaa gccaaaccaa 3441361 gtgtaattaa actctttctc actttttata tcctcccttt tactgtgaac ctgtcctcat 3441421 ttggaatcgt attttgaaca tcaagtttcg ttcctcatac tctacgagga atgatggttg 3441481 tttatggtta attattctgt gcatctctta ttctggttgt atagcgttta tttcacatca 3441541 tatgtaaaaa acactaattc cttatgtacg agaatcatta taccatcaag tttcgacaaa 3441601 ttagcgataa attttattac atttatgttt caaacagatg tcaagtcaca catcatttgt 3441661 catttttctt aagcgtgtaa aaaaactgtc gatattattt tcttaatata atctatctaa 3441721 caaaaaaaga gtcgattaaa taaatcaact ctttaaaatt tactattcta gaatatcatc 3441781 aatatatttc atatatttcg tcaaagttgc cggagagatg ccgaatcggg ccgctgtgtc 3441841 ttttttcgtg tcttgcttgc catgggcttc tttccaaata taacagatgg ctgctgccca 3441901 gcctttctca ttcttcaacg gagcagctgc acgaatttgc tggatgacat gaaaaaccca 3441961 gcagctcatg acttctgttt tcatctcttc tttttcagct tgctctaata gtttgaccgt 3442021 ttgataagcg aaaagtgcat cctctgaaac gtcagcagcc gcagaatctc cattcagaag 3442081 cagctttaca aaatgagttt caaaaggagc ggtaattctc tttgagcgta tcaccgcttc 3442141 aagatgctct gtttctccct ttgtgctgct gatataatag gctgcgagtc gctgctccac 3442201 agatgaagga agagcttccc tccgctcaat ccaaggcgcc gggcggtctt cgccgggata 3442261 ttgcgactcg acttttctcc agatcgtctc ggcaaagtcg gtatgtcccg taaaataagc 3442321 agagcaggaa agccagtaaa agaaggtgtc gtcaccctca aagccggttt tatataatga 3442381 tttgagccat ttatatccga tctcgtagcg gccgacaagc gccaaagtag cacccaattt 3442441 ataacgctgc tccaatagca tcggatagac attggagagc tgatcactca attccgccac 3442501 tttttcgtct tctctttcat aatagtagaa aacgagaaga ttgcataagg cgtgaagatt 3442561 tccttcatta tgagaaagca cttcataagc ggtttgcttc gcttttacaa cgtttcctga 3442621 atagaaatag gcaagcgcga gattgttgta tgctgaccaa agctccggat attcagttgt 3442681 gatttcctca agcgccgcaa ccgcttcagc aagctggccg ctttccagca atgactttgc 3442741 ccgatcctgt ttcaccagca gttcatcctg atcatacaac gaatcctcaa tgccgtcgtc 3442801 tcctaaatcg agcaaatcaa gcagactatc gttttcttcg gcgaattcac catccgggtc 3442861 cgcatcagaa taagcggccg cttctttata agcttcctgg aagagcccca gatgggcaaa 3442921 gttattcgct ttaaagtaat ggcactccgg catttcggcc tccagatttg ccatgatata 3442981 gtcaagaaga tcgttcgact cttgatactg gcccatttcc gaataaatga ccgcaagctg 3443041 tgaaagcatc tctgaatcct ccggctccaa atgaaccgcg cgctgaatca gtttgcttgc 3443101 ccgttttaga ttgcgctctt tatacgcttt caagccttta tgaaaaaaat attgtccatc 3443161 ttgaagcagc tggacaattt gtgcgtgatt tttatgttca gaagtgtgtt ttcccacaac 3443221 taccctccgt tttatacaat attaccgtca gtagtatacc ataaatcgta agcccctcaa 3443281 tagttcaaaa ggaaggattg ggaaaatccc tcctcttttt tattggctga ttcgaccaaa 3443341 atttacccgg ctttgttttc taagtccgca ttcattttca gctgctgttc agcaaaatcc 3443401 cggtaaaggc catgggaagc cattaactca tggtgtgttc cacgaccggt aatttcccct 3443461 ttttcaacaa acaaaagctg gtccgcatct acaacggtag ataggcggtg agcgataaca 3443521 atcgttgtgc ggccctccat cagcacctcc agcgcctgct gaactgattt ttcagattgg 3443581 ctgtcgagac ttgaggtagc ttcatcgagc ataagaatgc ttgggttacg gagaagcgct 3443641 ctcgcaatcg cgattctttg cctttgtccg cctgacagca taatgccgcg ttcgcccact 3443701 tctgtatcaa actgattcgg cagctccttt ataaaattga gcgcatatgc catctccgcg 3443761 gctttttcga tctcagcatc cgtcacatct cgttctaacc cgtagcaaat attttctctg 3443821 attgtcccgg acattaacgg gctttcctgt gatacatacc cgatatgctc cctccacgat 3443881 tcaagcgagt aagtatcgac cggctcgtcc cccagccgaa tggtccctgc agtcggagaa 3443941 taaaagcgtt caagcagctt aaacagcgtc gtttttcccc cgccgctcgg accgacgatc 3444001 gctgtcactt tccctgcttc aatgacggcg ctgacctctt ttaagatcag ctgatcaggc 3444061 ttatatccaa aagacacgcg atcaagctgg ataggcagat gtgcattttc aatttgtttt 3444121 cctgtcactg tatcttcctc ttcctctgcc aaaatctcaa tcattcgttc tgttgcaccg 3444181 attgattttt gcagctgtgt gaaaaacgtt gtaatctggc ccatcggcat aataatttga 3444241 aacaaatata aaataaaagc cacgagcgct ccggctgtga gctcgcctga tgagacctgc 3444301 atgccgccat atccgatcac tgcgacaagc gctgccatta acacgagtga aataagcggg 3444361 ccgacaagcg attgaacctt ggcttcacga acgccaagct taaataatga ggaaatcccc 3444421 atcttcccgc gcccatattc gacatcctcc gcatttgaag ccttaacaag tctgatttcc 3444481 gggagaattt gattaagcag gcctgtaaaa cgagccgttt catcttgcgt ttcccgtgaa 3444541 atggagaaca ttttccgtcc aatcggcacc aaaataagag cggccagcgg aacgaccact 3444601 aacacaagca gtgtcagctt ccagttcata ataaacaaga ttgtcaatga tccaatgaca 3444661 gaaatgatgc ctgtaataaa tccgctgata tgggttgtaa tcaattcttt gaccaccatc 3444721 gtatcgttcg ttacacggct gactgtttct ccggaagcat ttgtatcgaa ataagagaca 3444781 ggcagcttaa ttaatttctt ccataataac tcccgcagcc cggaaatgat tttttgtcca 3444841 ttatagttaa gcgcataggt ggcataagcg cttaaacccg cctgaacgaa aaacaccagc 3444901 gcgatcaaac cgatttgcgt gcctgacaga tttgacatag aaaaaccatc gacaagctgc 3444961 ttcgttaata atggaatgag caggctgacc agcgtggtta ctacactgag ggcaagcgca 3445021 aaggcgagct ttccataaga aggattggtc cgtcttacta aggcaaaaaa gggtttcaat 3445081 ttacttttag atttttgttt cttggttggc atatattttc ctcctgtttc agcgttcaga 3445141 aaggtgaaaa gtcatagcaa aaggatgatt tttactcttt ctcaatcata tcaatggaga 3445201 aagacttttt cagtatattt ttgccgtgat caaaataaaa atctcccact cattgtttga 3445261 ataggagatt tttgtgttag acatctttca ctggcttctt ttttctgtaa gtcaatgtta 3445321 catcctgctg tcgcaggtct tctattatca ttttgtaccg atcaactttt gcggtatgtt 3445381 cttcttttat catctgaagg gcagcttttc gtttttcgct attagactca agctcttttt 3445441 ttattttttt tacaatcaac cctttttgcc ctttgatttc ctcttttaat gaagactcaa 3445501 atttctttgt caggctgaga aagtcgttga tcggttgatt gagggtgccc gctttcccct 3445561 tcatttcatc ttgggtaaga aacatatagg tcgttgatac aatttctgtt tcactttctg 3445621 aaaataagga agtcactctt catattcctc ctaagactga aaatcaaata actgagaaat 3445681 catttcttct ttttcaaaca gcttttcaat actctcgcgg atatttttga taaaatctct 3445741 tttttctgtt gtctgttttt ttaattcagc aacaattcca tcatttgcag gaagcgcacc 3445801 tgtgtggaat gattcatgaa ctgagatttt ctccaattta tcgaatgtgt ggctgaaacc 3445861 agctgcaagc cggaattgaa gatcgaaggc ataatgcgaa gggttttctt ccatatgatg 3445921 aatagccgtg atgatcgcct gctttttgtc tatgaagtct tcatcgattt cctgactgta 3445981 aaccttctgg tacttagaaa tcgcatcttc catatcttca acgattttca taccgttttg 3446041 atagattctg acagcggatg agagattgac ttgaatcgtt tctcccgagc cactcttccc 3446101 tgtaaaataa atatcggagc ctttatagct gaagcctttt tcctttgaca aggcgttgag 3446161 catttgaacg atgctgtggc cgtcgacgat aagttttagt gcgtcttttg tttctgtgtc 3446221 gagtgttttc aatgaggaca gaattgattt tacatagtcc actatttcac caacgtcttt 3446281 taaagcttgc ataaattggc catgttttag atggtctatg aaatgttcgt accgtgactc 3446341 tatgcctcgc atactcgcat taatattcgt taattctttt ttgatgactt tcttttgcgt 3446401 ttcatcaata taaccatttt cagctaactg atctacgacc ggtccgctgt ttctcaacaa 3446461 ggtatgaaga aaacctaaaa acgacggcag ttcctctttt attcggccat acatttgctt 3446521 aacatcatca aaatgctcat ataggacact tactttcttt aaagcgccgt ctgtgttttt 3446581 cactttttca atcaggtcta tgtctatccc gctggctgcc tttataaaac cgttcaagcc 3446641 gtctttttca tagtcatcct tatatttttg aaggaatttt tgaattgacc tcacatcttc 3446701 gtcaggaacc ccatccataa tgtttcggat gccttttaca cttgtatttg tatctgccat 3446761 cttcacatca ccgaatgtaa taaaatcggc cttgccgctg actccataca gcgggtcatc 3446821 ttttgagatg cgctgagtga tgtttgttgt tacgcctttg tcttcataat atttttggat 3446881 ttcttttttt aacttttctg gcgggatgga atctatatct tcatatttat aactaaattt 3446941 cctaataaca tatctatata aactttcatc agtttcaagt aattgatcaa tattgacttg 3447001 agctccattt accccataaa cttcatcata ttctccatca atcaattgca ccataacttg 3447061 gttattattt gcaagtgaat gtcctaaggc gaatgttttt aaatcctcag agttacctgc 3447121 tgctttcttt gctttgttag taaactcctt tgtagcctca tactgactat gatcaattcc 3447181 taaaaaaaga ccaaaaaagt tatatgacca atccttatta tcggcactac cttctgaaat 3447241 aatctgaagc tgatcaatat gttttttctc atctattata tggattgccg ttccatcgta 3447301 acctgattct ctggtcgaac tttgtatact tgtattctga tttacaagtt cattggaggt 3447361 gtaaatttca attttcatat tctcaggaag atcgtggtgg gtttcctctt tataaattct 3447421 gcgtatatct gcttcgaaat ccttcttagc tttcttaact tcactcgcaa tagttgaggc 3447481 aaacttttgt ttatagtcat attctaaatc aattaacctt aactttacgt tctcattctc 3447541 aaatacattt ttatttccca tcttatttct cctttttatc tattaaaaag gtgatagaat 3447601 taattaattt ctcaacttta tttttagcct tttcttcatc taaggagcat ggttgatttt 3447661 catttttgca tccaagggta aaggcgtatt ctactcctag gttatcttcc tctgtagact 3447721 taacatatcc aaaataactg tatgaataat tatattttct atcaatatcg tcaaagatgt 3447781 cttttttctt ggcagtgtaa atatccgttt tctttttgct gctttttttg tattcgcctt 3447841 tataatcatt ttttccacta acaatatcta gcattgtctt aggttcattc gcaaaacttt 3447901 cttctttgta atatgttaca tggccatcaa acattacatt ggtgtcttta tcataactat 3447961 taaatccaat actttctttg tttttcccgg ttaacgatga tcttcttgat agatactttc 3448021 catcctccgg aaacaacatc ctaaaccctt tcagcttaga ttccagcaaa taatatcctg 3448081 gttcctcttc ttttgttgac accatgtact ctctcgtttt ctcgtcctga aacgcaggta 3448141 cttgaggcag atccttggga tccatgtctt ttggttttac cgcttctgtt ttattgtcat 3448201 ttgtgctgtt tttatcattg tcattcatac tgcatcctcc tgtcagggca agtaataagc 3448261 tgaagcaaat aaagatgatc tttttcatta cgaacctcca cgggttttgt gagaatagta 3448321 ttctattttt atatcaaaaa taattctatt gacctggtta agagatgatt atttcatcct 3448381 ttttcatgtt acatcatggc ggaatttgga taaataggaa atgagactcg gttttgatct 3448441 ccttttatta actaatcata tataacaccc aatataaatc taaataccta ttactttttt 3448501 cacaaaacaa aaagagccgt atcatccggc tctttactct tcaatctcag aatggcgttt 3448561 tttcaatacg tcaagcacat catccagcgg cagggattgt tctctgagca ggacaagcag 3448621 gtgatacagc aggtctgccg cttcccattt gagttcctca tgatcccggt ttttcgcggc 3448681 gatgatgact tcggatgctt cttctccgac ttttttcaaa atcttatcga cgccttcacg 3448741 gaagaggtac gtggtgtaag ctccttcagg catttccgct tggcgttccg cgatcacccg 3448801 ctccagttcg ttcatgatgc cgaatcggtc cgcggcctgt tcttctgttt gttcctttgt 3448861 aaaacagctg tagctgccag tgtggcatgc cgggcctgac ggttctacga gtacgagcag 3448921 cgcgtcttga tcgcagtcat accggatacc tttgacggct tgcgtgttcc ctgaggtttc 3448981 tcctttatgc cataacgctt ggcgtgagcg gctgtaaaac catgtttcct tcgtttccag 3449041 cgttttttcg tacgattcct tgttcatata cgcaagtgtc agcacttctt tgcttgccgc 3449101 atcctgcacg atagcaggaa ttaatccgtc ctcgttaaaa cgcagttcat ctgcctgttt 3449161 catctcacat tcaccccgta ctctttcaag tatgatttca cttctttaat cgatgtttct 3449221 ttataatgaa aaattgaggc ggccagcgcg gcgtcggctt ctccttttgt aaaagcctca 3449281 agcatatgct gtgcgtttcc cgcgcctccc gaagcgataa cagggacggg gacagcttcg 3449341 gaaacaagct ttgtcagcgt gtggtcgaaa ccttttttct caccgtcgga gtccatgctt 3449401 gtcagcaata tttctcctgc cccgcgtttg acgccttctt ttgcccacgc ggtgacctcc 3449461 caatctgttt tctttctgcc gccgtgcgtg tagaccttat atgtgtcaga ttctttgtca 3449521 tacttggcat caatggcaag tacgatgcat tgagaaccga aaaactcggc tccttctgta 3449581 atcagctcag ggcggagaac agctgccgtg ttcaccgaca ctttgtccgc tccggcacgc 3449641 agtatcgttt tcatatcgct gagctgattg atgccgccgc cgactgtaaa cggaatggca 3449701 agcttcgcgg caacctgctc cacaacgtca accatcgtct ttcgtccttc gtgcgaggcg 3449761 gagatatcaa gaaaaacaag ttcatccgca ccttcccggt cgtacacttc ggcgagttca 3449821 actgggtcac cggcatcctt caattcgaga aattgaattc ctttgacaac gcgtccttct 3449881 ttgacatcaa ggcatgggat aatccgtttt gtgatcattt gcgcttcacc ctttcaagcg 3449941 cctcactcag cgtaaactga ttggtataca gcgcttttcc gatgatcgct ccagagacgc 3450001 cgtccgcctc attgcgggcg agagcttcga gatccgcgac ggagctgact ccgccggaag 3450061 cgatcaccga tttccccgtt tccttagcaa gctcgaccgt gcttttaaca ttggggcctg 3450121 acagcattcc atctgtcgcg atgtcagtaa aaataaagac ttccgcacct tcattggcta 3450181 gctctttgcc cagttcagtt gccttaaggg ttgatgtttc aagccatccc tctgttgaaa 3450241 caaaaccgtt tctcgcatcc agtccgattg caattttctc gccatattgt ttcagcattt 3450301 ttttgacaaa cggagggtta gaaactgctg agcttcccag gatcacccgc tcgactcctg 3450361 ctgataaata ttcatagacg tcattttcag aacggatccc accgccgatt tcgactttca 3450421 ggttcagctt ttgcgcaatc tcaatcacat ggcggtcatt cactcttttc ccttctttgg 3450481 ccccgtcgag atcaacgaga tggatccatt cggcaccctc tttctcaaat aactcagcca 3450541 tgtcgtacgg tgaatcgcca tatatcgttt ccttattata atccccttga acaaggcgaa 3450601 cacatttgcc gtttctcata tcaattgccg gatataatgt aaaagcactc attttttcac 3450661 cttctgttct gctgccattt tcgtaaattg ggttaaaata gacattccga ccgtgctgct 3450721 tttttccgga tgaaattggg cgccgaagac gtttcttttt ccgactacag caggcactcg 3450781 tacaccataa tcggcgcttg ccagaagcgc gttctcctcc atcccgtcaa tgtaatagga 3450841 atgaacgaag taagcgtagc cttgttctgt tttagtcagc agcggagatt cattatgaaa 3450901 agaaagacga ttccagccca tatgcggaac cttcagcttg tttccttttt catcttctgc 3450961 tttcagcctg actgcttttc cttttaacag cccgagtcct gaagcggtgc cgttttcttc 3451021 gctttcttca aataaaagct gcatgccgag gcagatcccg agaagcagcc ttccctctga 3451081 gaccatatcg tgaatcaatt gatcaagctt cgtgtagccc aaattgtcca tcgcgtctcc 3451141 aaatgaaccg actcccggca aaatgaaagc atcagcttct ttcagctcct ccggcttttc 3451201 agaaacaaaa tacggcacgc cgacacgttc aagcgccttt gagacactgt ataaattccc 3451261 cattccgtaa tctatcacgc cgatcattta cagcatccct ttcgttgacg gtattccttt 3451321 aactcgcgga tcgatcgttg tcgcttcatc aagcgcacgt cccagtgctt taaaaacggc 3451381 ttcaatcatg tggtgggtat ttgttccata atgaacgatg acgtgcaggt tcattcgagc 3451441 ttcgagcgcc agcttccaca aaaattcatg tacaagctcc gtatcgaaag ttccgacttt 3451501 agcagccggg aaatcagcgc gcatttctaa gtgcggccgg ttgcttaaat caatcacaac 3451561 ttgagcaagt gcctcatcca tcggcacaaa cgccgatccg tagcgtttga ttcctttttt 3451621 atcgcccaac gcttcgagca gcgcctgccc taagcagatg ccgatatctt cagtcgtgtg 3451681 gtgatcatct atatcaacat cgccttttgc gttaatggaa agatcaaatt ggccgtgttt 3451741 cgtgaataaa tccaacatat gtgtcataaa cggcacatct gttttaatat ccgcttgtcc 3451801 tccgccgtct attgtaaatg ccagctcaat atctgtttcg tttgttttcc tgacgcgttc 3451861 cgcttttctc atttagaaat cctccgttct ctcgcttcaa ttgatctggc atgggcttct 3451921 aacccttcca gtctggcaaa agccgcgatg ctttcggcat gttcttcaaa ggctgattga 3451981 ctgtaagaaa taatgctcga tttcttttga aaatcagtta cgtttaatgg acttgaaaat 3452041 ctggctgttc cgtttgtcgg aagcacatgg ttcggtccgg caaaataatc accgacaggc 3452101 tcagggctgt atctgcctaa gaaaattgca cccgcatgtt tgatactgcc aagcaaagct 3452161 tccggagact gtgttatgat ttctaaatgc tctggcgcga gtgtattgac agtctcaatc 3452221 gcttctacca ttgtttccgc cacatatata caaccgtaat ctctcactga agcttccgct 3452281 atttctcttc gcggcaaggt ttccagctgc ttattcacct cggctgaaac cgtctcggcc 3452341 agcgccatgg aatctgtgac aaacacacat gagctaagct tatcgtgttc cgcctgtgac 3452401 agcagatcgg ctgcaatttc gctcggaatc gctgtttcat cagccagcac gacgatttca 3452461 ctcggtccgg caatcatatc gatatcgaca tcgccgaaca cttctcgttt ggcaagcgcg 3452521 acataaatgt tgcccggacc cgtgatttta tccaccggct caatggtttc tgttccgtat 3452581 gctaacgccg caatcgcctg agcgccgccc attttgtaaa tgtcttttat gcccagctcg 3452641 gctgcagcaa ccaaaactcc aggagacagc agaccgtctt ttcccggagg cgtgacgaga 3452701 acgattcttt caacgcccgc tacgagcgcc ggaatcacat tcatcaaaac agatgaagga 3452761 tatgcggccg ttccccccgg cacatataca ccggcggaat ccagcgccgt cactttctgc 3452821 cccagcattg tgccgtcctt tctgtgataa aaccaggagg attgcagctg tctttcgtga 3452881 tattccctaa tattttcgat tgcctgccta atcacctgaa gaagacgtga atccagtgag 3452941 gtgtatgcct cctcaaattc ttcttttgtg accagcgggc tgtctatttc gatgcagtca 3453001 aatttcgccg tgtagctgcg aaccgcctga tcaccgtttg ctttaacatc ttcaataatg 3453061 gaccggaccg tctttctttg ctcttccgtt ccggcatcga tggaacgctt gagagaaagc 3453121 cgttccgctc cgctgatggt tttgatcttc attttgccgt ctctccttcc acaacgagag 3453181 ataggcggga tgccatttcg tcaatcacat cgtctttcat gcgatagctt accgggttga 3453241 caataaagcg agaggtaatg tcacaaatgt gctccgtttc aacaagccca ttttctttca 3453301 gcgtctgtcc tgtggaaaca atgtccacta tccgatctgc aagcccaatg agcggagcca 3453361 gttcaattga accgttgagc ttaataatct cgacttgttc tccctgctct ctgaaataac 3453421 tggaagccac attcggatac tttgtcgcga ttcttggcgc tactccgctc cagtctgtat 3453481 tcggaagtcc ggcgacagct aagtggcatt tgctgatgtt taaatccagt acctcataca 3453541 catcgcgttc ctcctccagc atgacatcct tgcccgcaat tccgacgtct gccacgccat 3453601 gctccacata cgtggttacg tccatcggct tcgctaatat aaaccgaaga ttttcctccg 3453661 gcacatcgat gatcagtttt ctcgaatctt caaactcctc agggagcctg tagcctgcct 3453721 gcctcagcag ccctgccgct tcttcaaata tccggccctt tggcatcgcc attgtgagta 3453781 acttacccat tttgctcttc ctttctggca ccgataaaat aagtgacgtt tgcaaaagat 3453841 tttgtcatct ggtcgatatt ttctattccc gataaatctt gaagaaccac tttgttccct 3453901 ttcatgcgtt cttcattcgc ataagcgatg gcttgcgccc gctgctcttt gctgaaaata 3453961 acagcgtcta tttcacaagg ttcgtccttc atatgaaggg cttcaatcag ccggtcgatc 3454021 cgaagcccga agcctgttgc cggtgcaggt gaatcaaaat ggcccagcag cttgttgtaa 3454081 cggccgccgc ttccaatgac aaaaccgaca ttctcggcgt acacttcaaa taaaatccct 3454141 gtgtaatagc tcatgtggct gaccatattc agatccaggc ggacattttc cgtacatccg 3454201 taatcctcaa gaatgtccca cagcgccttc agctcatcaa ccacgctttt tccttgcgca 3454261 gaatcgacga tttcctcggc acgtccgcat acttctatac cgccccgcag ttcaaggagc 3454321 tcaagcagcc tgcttttatc aatggaggaa agcgggagag acttgacatg ctctctgtag 3454381 ccgacgtagt tcttttcata taagaacctc cgcagcacat cagctcgttc aacgtttccg 3454441 agcacctcaa caaacaaagc atccgcaatg ccggcatggc caattgcaat tttaaaggat 3454501 gccagcccag cgttttttaa tgccccgacg actaaagcaa tgacctccgc atccgcgctc 3454561 gtcgtgccgt caccgattaa ctccactccg acctgctcga actcagccgg acgtccgcct 3454621 tcacgctcct gagccctgaa tacatttgcc gcatagccga ctcttagcgg atgaccgtgt 3454681 ttcagaagct tcgatgccgc cacccttgca atcggccccg tcatatccgg gcgaagcacc 3454741 aatgtcttgc cgtcctgatc aagtagctta aacagctgct gctcttcaat tgctgactgg 3454801 acgccaacgg tatcgtaaaa ctccagtgtc ggcgtttcca taaattgata tccccattta 3454861 tcaatcaaat cggttaacga tcgtctcacc ttttttttcg tttcgtataa accgggcagt 3454921 gtatctctca tgccgtgcgg tttttcaaac ataaacatca acccgagcac ctccgctgtt 3454981 atcttatgaa ggaaaattcc gaatccttta gttcgctaat atgataatat gttagcagat 3455041 gaaagaatga aaatcaacgc ttaacttcag taaggatatt tttagttcaa atatccttct 3455101 cctcattatg aaaaaatcat gaataatgta ttaaaggtac gtaatatctc aaattcttta 3455161 tgtttggcat gctataatac aaatcaaata gagaacaagg agataaagat gaaaacactg 3455221 cgaactctat gtgtcctgat gattctttca ggcgttattt ttttcggact taaaatagat 3455281 gcaaaagata tagatattcc ttttttgaac agccttaaaa aagtggtttc tgatagcgat 3455341 acagactcag ctgcgaatag caaaaaggag ctgaagggaa gcgcaaaacc gctggatgtc 3455401 atcctttaca atcaaatgga cgcaccccgg ctctataacg gctgtgaagt aacaagcctt 3455461 gcgatggtgc tgaattatgc gggatacgac gtgacaaaaa ataccctggc aaatcaggtt 3455521 gccacagtgc ctttgacata cagcagcgga ttaaagggtg atccgaatga cggatttgtc 3455581 ggggatatgg cgaatggccc tggtctcggt gtctaccatc gaccgatcta tcagctggcg 3455641 aaaacctatg cgggagacaa agtgtctgat ctgactggaa aaagtatttc cgctgtttat 3455701 cagcagcttg aaaaaggcaa tccagtttgg gttattacga cagccaactt tacgccagtt 3455761 gacaacatgc agacatggaa aacgccaaac ggaacgatag aaattacgta cagcgaacac 3455821 agcgtcgccg ttacgggata tgatgataaa tatgtgtatc tcaatgatcc gtatggctat 3455881 aaaaacagaa aaaccgatag aacaagcttt gaaaaagcgt ggaaacaaat gggcagccag 3455941 gccgtggtta ttcaaaagta aacacctgaa gcctcactat gctctattct gagcaaatac 3456001 gacaatattc atgctttttg tatcaatcgg taagatcgat tcattttcca tttttcaccc 3456061 aaaattgtct ttactttcag gctgtctgtt tttatgatta aagcagattc agccttgccc 3456121 cgatctatgc gagagaagcc ggtgcaagtc gctgacgctt ctcttgcaaa aaatgaaaga 3456181 tatccgggga ggatttatca ttgaaaaaaa tcgtgtctat cctatttatg ttcggtttgg 3456241 ttatgggttt cagccagttt cagccatcaa ccgtttttgc agctgacaaa gtggtgcacg 3456301 aaacaattat cgtaccaaaa aatacaacat atgacgggaa aggacagcgg tttgtggcag 3456361 ggaaagaatt aggtgacgga agccagtcag aaaaccaaga ccctgttttt cgtgtggagg 3456421 atggagcaac cctgaaaaat gtggtgcttg gtgcacctgc agctgatggc gtgcacactt 3456481 atggaaacgt taacattcag aatgtgaaat gggaagatgt tggtgaggat gcgttaacgg 3456541 tgaagaagga aggaaaagtg acgatcgacg gcggttctgc tcaaaaagcg tcagataaga 3456601 tattccaaat caataaagcc agtaccttca cagtgaaaaa tttcacggcg gataatggcg 3456661 ggaagttcat tagacagctt ggtggttcaa ccttccacgt tgatgtgatc atcgacaagt 3456721 gcaccatcac aaacatgaag gaagcgatat tccggacgga cagcaaaaca agcacggtca 3456781 gaatgacaaa tacacgctac tctaatgtcg gtcaaaaatg gattggtgtt cagcatattt 3456841 acgaaaacaa caacactcaa ttttaacaaa aaaagtccgc tgatgttatt cagcggactt 3456901 tttcaatctt tcttgcattt cttccttcgt atagatgatc ctcatcggat ttccgccgac 3456961 aaatgccccg tcaggcacat ccttatggac aagcgttccg gcggacacaa ctgcgccatc 3457021 tcctattttc accccgggca gaatggtcgt gttggcacca atcatcactt cgtccccgat 3457081 cagaactttg ccgatccggt attcgtgaat caaatactca tgggccagaa tggtcgtatt 3457141 gtacccgatg attgtatttg ttccgactga gatcttttcc ggaaacatga tatctggcat 3457201 caccatgagg gcaaaggatg tctgttttcc aaccttcatc cgcagaaatg tgcggtacag 3457261 ccagtttttc atccctataa acggcgtata tctcgcaatt tgaatgacaa tgaaattttt 3457321 gacgaccttt aaaaaaggta ccgtttgata gacatgccac agtgagttgg cccccgagac 3457381 cggatgacga tctgtttttc tcacagatta cttcactcca acgatttgta atagatcact 3457441 cattttctca agcataaaat ccggctcatg cttcgccagc atttccggcc ctttaatcgt 3457501 ccatgcgact cctgccgttt ttgtaccggc gtttttccct gccagcacat catggtaatt 3457561 atcaccgacc ataatggctt ccgccggctc gcttcctagc tgtttcagcg ctaacagcac 3457621 aggctcggga tcaggctttg cattcgtcac atcatcaagg gtgacaactg tttcaaagaa 3457681 ttcgccgatt cccgtgagct tgaggcccat attgacagta tctcttaatt ttgttgtcac 3457741 aattcctaat gtaaagccgg ctttttttaa tgcatccagg gtctcatata ccgtttcata 3457801 ttcagtgacg agtgaatcat gcatgtcatg attgtacgct ctgtacatag cgatcatatc 3457861 ctcgcattta tcagggtcca tcgaagagaa cgtatcaaaa agagacggcc cgataaatgc 3457921 aaggacatct tctcgtttat acttgctcgg ataataatgc tccagtgtat gcaaaaagga 3457981 cgcgataatt aattcattcg tattaataag cgttccgtct aaatcaaaca gaatcgtcgt 3458041 tacttgtttg tcactcatat tgcttccttt ccaaccgctg agggtttcca ttttttccac 3458101 gtgtgcgcaa tagccattgt cagcagaact gctgtggtga cacgaatcaa aagaagcggc 3458161 cagaccggta tgccaagcgg aataaagaca agtgtatctt ccacgaccgc gtggcaggca 3458221 acgagaaata taaatgccaa tgtcatgtcc cgcttgctca cgccgtcatc ctcgacagct 3458281 ttgatcatga cacccgctcc gtaggccaga ccaatcgtca gtcccgtcac catcgtcata 3458341 gacgtatttt tattcatgcc aagcagctgc gtaaacggcg acagccacct ggaaaaccga 3458401 taaagccagc ctaaatctct taaaaactgg atgataatca tcagcgggat cactattgcc 3458461 gccagctgca aaacaccaag tccggctttc gttaatgctt ctgccaacat tcctagccag 3458521 ctgtctggcg ccgcgctctt cgcagcgata aaaccgtact gcgccgtttc ctttccgcca 3458581 tgccaaatga ggttgatgac gatggctgac acagcggcca aaccgatgcg cacggccaat 3458641 atgacgccaa ttctgatacc aacctttgcg gcaactgtcg attcgataat caagttatga 3458701 cagaaagaaa gcataacagc taaaataaag acttctttca cagataaatc caatgttaaa 3458761 atcccggcaa ttcccgcata cagattcagc atatttccca gtacaagcgg aatggccgct 3458821 tcaccagaaa gcccgaagag acccattacc ggtgtgatca gccgtacaag ccaatccatg 3458881 acaggggtat gctggagcaa agtgaccaat agcgttaccg ggaaaatcac tttacccagc 3458941 gtccatgttg tttgaaaacc tgctgcaaga ccggccagaa agatcttctt catccctcat 3459001 ccccctttgt tgacgtctac tccgcgtacc gctccttcga gtatcccttg acgcgtctga 3459061 agatgatggc tgccacagcc aaaacaatca atacgattga aatcacctga gcgatgcgaa 3459121 gtgaatcagt cagcattaag ctgtcagtcc gcattccttc aataaagtat cttccgattg 3459181 aataccaaat gatatagatc aagaacatct cgcctctacg caaattcgct ctgcgcagca 3459241 gcagtaaaac aatgacgccg acaaagctcc atagtgattc atataaaaaa gtaggatgat 3459301 aatattgccc attgatatac atttgattga tgataaattc aggcaggtgc aggttttcta 3459361 aaaaggctct gctgacagcc tcgccgtgcg cttcctgatt catgaagttc ccccagcggc 3459421 cgatcgcctg gccgagcaaa atgctgggcg cggcaatatc cgcaagcttc cagaacgaaa 3459481 ggtttttcac tctcgaaaac acataacccg ttaaaatggc gccgattaat ccgccatgaa 3459541 tggcaatgcc gcccttccaa atcttaatga tttctcccgg atgtgccgca taatagtccc 3459601 attcaaaggc aacataataa attcgtgcgc aaataatcgc aattggaatg gcaaacagga 3459661 caagatcaat aaacgtatct ttctgcagcc cccgtttttc actttccctc atcgctatcc 3459721 acagcccgag caaagcgccg agaccgataa tgattccgta ccagtggacg gctaacggcc 3459781 ccagctgaaa tgctatcgga ttgagtggtt ctatcgcttc attcatttaa cgccaactcc 3459841 tattcttctt gttcaccgtc ttcaatgacg tccgccagct tgttggtaaa ttgttcagcg 3459901 gcattcagcc ccatccgctt caatctgaag ttcattgctg ccacttcgat gatgactgca 3459961 agatttcggc ctgggcggac gggaatcgtc agttttgtaa tttctgtatc aatgattttc 3460021 atggtctctt cctcaagtcc gagccggtcg tattgcttgc cctgctccca gagttcaaga 3460081 ttcatgacaa tcgtgattcg tttattgctt ctgaccgcgc cagcgccaaa tagcgtcatc 3460141 acattgataa tgccaaggcc cctgatctca agaaggtgct caattaattc cggagcgttt 3460201 cccacaagag tatcctgatc ctcctgccgt atttcaacgc aatcatcggc aacaaggcga 3460261 tgccctcttt tcacaagctc tagcgctgtt tcgctttttc cgacgccgct ttttcctgtg 3460321 atcagcacgc cgacaccata tatatcgaca agaacgccat gaattgctgt ggtaggcgcc 3460381 agcctgctct caaggaagtt ggttaaacgg cttgacagtc ttgtcgtttt cagcggcgat 3460441 ctgaggacag gcaccccatt tttctcggag gcgtcaatca gctcctgcgg gatgggcata 3460501 tctctagaaa gaataatagc tggtgttaca tcagtgcaca gagaatccat tcgctgcttt 3460561 ttctcctctt caggaagctg ttcaaagaaa gaaagctctg tttttccgag aagctgcacg 3460621 cgctccctcg ggtaatatgt aaaatatccg gcaatttcaa tacctggtct tgataggtca 3460681 ctcattgtaa tcgggcggtt aattccttct tctccgctga ttaattccaa attgaactgt 3460741 tccattacgt cttttgtgcg aacctttgcc acgatatgtt cctcctgttc cgggctgccc 3460801 cgagcttgct cacaatactt tcattttatc actttcgggc ttgaacctaa aacagatttt 3460861 ataaaagggg ggaaaacacc tcagctggtc tagatcacta gtctgaaaaa gagtaaaata 3460921 aaggtattca aattccagaa aggcggatca tctatggcag agagtcttct tatcaaagac 3460981 attgcgatcg tgacagaaaa tgaagtaatc aaaaacggct atgtcggaat caatgacgga 3461041 aaaatcagca cagtttcaac agaacggccc aaggagccat attcaaaaga gattcaagca 3461101 cctgcggatt ccgttttgct tcccggcatg attgacattc atatccacgg cggctatggc 3461161 gcagatacaa tggatgctag cttttccacg ctcgacatca tgtcgtcaag actgcccgaa 3461221 gaaggcacga cgagcttttt agccacaacg attacccaag agcatgggaa catttctcaa 3461281 gctttggtga acgcaagaga gtggaaagcg gctgaagagt cctctttatt aggtgcagaa 3461341 ctgctcggca ttcatttaga gggccccttt gtttcgccta aaagagccgg agcgcagcca 3461401 aaggagtgga ttaggccttc ggatgttgag cttttcaaaa agtggcagca ggaggcgggc 3461461 ggactgatca aaattgttac acttgcgccg gaggaggatc agcattttga actgatccgc 3461521 catttgaaag acgaatcgat tatcgcatcc atggggcaca cggatgccga ttccgcattg 3461581 ctgtcggatg ccgcaaaagc aggggcgagc catatgactc atctgtacaa cgcgatgagc 3461641 ccgtttcatc accgagagcc cggagtgatc ggaacggcgc tggcccatga tgggtttgtg 3461701 acagagctta tcgccgatgg cattcactcc catcctttag ctgcaaagct tgcttttttg 3461761 gcgaaaggca gcagcaagct cattttaatt accgattcca tgagggcaaa aggactgaaa 3461821 gacggcgtat atgagttcgg cggccaaagt gtgacggtaa gaggacgaac agcacttctt 3461881 tcagacggaa cccttgccgg ttcgatcctc aaaatgaacg aaggcgcacg gcatatgcgt 3461941 gagtttacaa attgctcttg gacggatata gctaatataa cttctgaaaa cgcggccaaa 3462001 cagctgggca tctttgaccg aaaaggcagt gtgactgtgg gaaaagatgc agatttggtg 3462061 attgtcagca gtgattgcga ggtgattctc accatttgcc gcggaaacat tgcatttata 3462121 tccaaggagg ctgaccagat atgaaagtaa tggaatgtca aacgtatgaa gagctaagcc 3462181 aaatagcagc cagaataacg gcagatacaa tcaaagaaaa acctgatgct gttctcggtt 3462241 tagcgacggg cggcacaccg gaaggcacgt atcgccagct gatccgcctg caccaaactg 3462301 agaatctctc atttcaaaac atcactacag ttaatttgga tgagtacgcc ggactttcaa 3462361 gcgatgaccc gaacagctat cacttctata tgaacgaccg tttttttcag catatcgaca 3462421 gcaagcctag ccggcatttt attccgaatg gaaatgcaga cgatttggag gccgaatgca 3462481 gacggtatga acagctagtc gattccctcg gcgacactga cattcagctt ctcggcatcg 3462541 gccgaaacgg acacatcggc tttaacgaac cgggaacgtc tttcaagtcg cgaactcatg 3462601 ttgtgacatt aaatgagcaa acccgccaag cgaatgccag atattttccc tccatagaca 3462661 gcgtgccgaa aaaagcactg acaatgggaa ttcaaacgat actctcaagc aagcgcattc 3462721 tgctgcttat ttctggaaaa agcaaagcgg aagctgttcg taagctgtta gaaggaaaca 3462781 taagcgaaga ttttcccgca tctgctttgc acctgcattc cgatgttacg gttttgattg 3462841 atcgtgaagc cgcgtcatta agaccttgaa aggaacatgc tgacttatga atatcaataa 3462901 acaatcgcct attccgattt actatcagat tatggagcaa ttaaaaaccc aaattaagaa 3462961 cggagagctg cagccggata tgcctcttcc ttctgagcgc gaatatgccg aacaattcgg 3463021 gatcagccgg atgacagttc gccaggcgct ttctaattta gttaatgaag gcttgctcta 3463081 tcgcctgaaa gggcggggca cctttgtcag caagccaaaa atggaacaag cacttcaagg 3463141 gctgacaagc tttaccgagg atatgaaaag ccgcgggatg acaccgggca gcaggctcat 3463201 tgattatcag cttattgatt caactgagga gctcgcggct atattaggct gcgggcaccc 3463261 ctcctctatc cataaaatca ctcgggtgcg gctggcaaat gatattccga tggcgattga 3463321 gtcctcacat attccgtttg agcttgcggg tgaattgaac gaatcgcatt ttcagtcgtc 3463381 gatctatgat catattgaaa ggtacaacag cataccgatt tcccgtgcaa aacaggagct 3463441 tgagccaagc gctgccacca cggaagaagc gaatattctt ggtattcaaa agggagcgcc 3463501 tgtcctatta attaaacgaa caacatatct gcagaacgga actgcttttg agcatgcaaa 3463561 atccgtatac agaggcgacc gttatacatt tgtccactat atggatcgtc tttcataaaa 3463621 aaagcctcca acccttttta aggattggag acatggcgaa aatcaaactg gtctggtgcc 3463681 ggacgatatg tttctttttt cgtcttgaac ttccagatcg gtgatttcgt tttgccgtta 3463741 aaactgtctt ccactataat gtaccaataa taaacagact gcggttcaag atgatcccag 3463801 cggaattcag ctgtgtcccc gctcttcact tgctcccgtt ttccgagctc ttcattggta 3463861 tatacgttac attcaaaata atcggtttcc acctttttga ttcttggctt caaatcaagc 3463921 gaaagggaaa attcatcctt gttgccatag gtatccgtat catagtagtt cttatccttt 3463981 acatacggag agtacgtcga tacgtgcacc atgtcattgg cttggtcaaa ttgaagcaaa 3464041 cgcaaatacc cttggccgcc ttctggcccg ccctgataat cggccagcat ttgatgcaca 3464101 agacgatccg gtttcccatc accatcatca tccagctcat ctgtttttct catcgcacta 3464161 tgataatgcc cgctcaacac catcacgaca ttcgggttcg gctttacgat ttctttgaat 3464221 attttctctc cgattgggct tctgtttccg ctgaccagca aatactcatg aaaagctaaa 3464281 atggccatcc ggtcaggatg cttcttcagc acctgattca tccacgcgat gtcttcatcc 3464341 gtaatgcccc atcccatgta cagcatgata taatcattgc cgttgctaga aatcaggtca 3464401 taatgtccgc ggttattttt ataggaaccg ccataatgaa attttttatc aaaacgatcg 3464461 ctgccaaaat atttgccaaa cgccctgtag gagccgtcct tatgtccgac atcgtgattg 3464521 ccggccagca cgccgtaagg aattccgctc ttatccagaa cggacattga ccgatcagcg 3464581 tttttccact gtctgatatc ggcggaatca tctacaatat cacccgtgtg gaacacatat 3464641 ttgatattga gctgcttttg attatctttt atccattcgg tctgtttatc aaaaatatgc 3464701 ggatagcttt cggcgtaata ctgtgtatca gacatccaga caaatgtgta catatccttc 3464761 gcaggaggaa tttcatcctg tacaatcaca ttcattttcg actcccgtac aaaatcggcg 3464821 gcaatcacag acgctttcag cgtaaacggt ttgtcatcct tcgcgacgaa gctgtcaaca 3464881 ggctgccatt cgtttgtccg ataattccaa gcatacatcg tcacctttct ccccggcaaa 3464941 gaactgccct tccagactga ttctgccaga tcattctcat caattgatgg atcaaccgtc 3465001 acttcaaagc gatgataagg gaaaagctct ttgttttctg tcgatactgt ttttccatca 3465061 gcagctgata cccgctccaa ttctttattc gtaaatgggg tctccctttc cggcacaaag 3465121 cttttcggcg gttcagtcag tgacgcgtgc ttaaatattt tcacatgatt gcgcgctgta 3465181 tattgaaatc ccctataaaa accaacatcc atggcatcat tcgtcggatc tttcacccgt 3465241 acagaaagct tggccttatg cgtgtcggct tcgctgtcta taacctccgg ctggtccgga 3465301 tgctctcgtt cggttttaaa tatcctctca atcactgttt tattgcccgc gagatccgtt 3465361 gctgtcactt ttagagaatg ttttcccggc aaaaggtcag aagatgacgt atgatatggg 3465421 agtgtaatgc tttctccatc taacgacgcc tccgcttcct caattctgct ccatttatca 3465481 tacatatccg cctgcaggat aaggtttcct ttatacgttt gcccctcggt gatattcggc 3465541 tcaatgtgag gtcctgaatt atctacccgt acaaccaggc tgacattttc cttcccgtcg 3465601 cttgcttgaa tatggtgagc gccttcagaa agctttgatg tatcccactc cagcagctgt 3465661 gatgtaaata gtccgtcagg cagattgaac tgaaattgcc agcttttatt cgagcgctga 3465721 ttatcgccaa taaagagttc cttctcagga gacaccctct gatctctgat caccgttcca 3465781 tccgataaca ccaatcgggc gtttttgact aagaagtcat cacggttttc agccgtatca 3465841 aacggagaca ccttcgaacc tgaacgtatc gtaatacgct gcagctgctt ccctttccga 3465901 agcagtgtct ctggcaatgg aacagaatag gtgcggtatt tatttgttgt atcatcgaac 3465961 accttcagca ctttgccttc catcgttacc gcgtttttaa aataaaggtt cgttttcctc 3466021 gtatcgaatg caaaatatac ttctttttcc atcgcgggct ctgtcacttg ttttttcccg 3466081 tcaatccata gcttaatgct gtcagctcgc ccttctgtcg tggctttgag aaattgagtt 3466141 cccgacagcg tgtctctgtt ttcaatattc atccgcagac cgtgcgcctt gcttgtttgt 3466201 ttaatatcaa tcattttgac cggcgttctc gcttcattga tcccgtcccc ggccgccaca 3466261 taatactcta gctgatcctt cccgatcaat tcaggcgaat acacaatata atggaagaga 3466321 ttatcgttgc ggtctttttc agcaagaatt cgcttaaacg gtttgttctc atccgtccgg 3466381 tagtaaaagg ccactgtttt cactaggctt cggtcccgta tgtcagcccg cagctcaatg 3466441 ctttcagcag ggcggacagg cttgcggtca gtcaaatcct caatgaccgg cttttcttta 3466501 tcgagcttga ttttccgttt ctggtcgggc acctgtgcct gtaatacggt tccgggagac 3466561 ggattctttt ccccgattga aatgttcaga agttctgctg ttccgttcag tggatactta 3466621 taaagcactg atgacagccg gcgcagcgca tgtttccgat aatgcgcaac cgaaatgtcc 3466681 tttcctgtat tcgttgatat cacaacggcc cgcggcctcg tattggccat accctctgtc 3466741 tcgtctatca ccgcaagatt ttttccttct tttagttgtg tctgataata acgattgaaa 3466801 tccgctgacg tcaattctgg atgcccggca ggcttcagcc agacgacaaa cgtttcgccg 3466861 gatggtatca agatcctttc atcaggtctc caaatcagat cggagtcagg cccttctttt 3466921 gggtagcggt aacggatatg gtagtcttta aaatcaatcg ttctgtcagt cgtattaaaa 3466981 atctcaataa attcataacc gtctgcgcgt cctatattct tcgtatcaac cgccagctct 3467041 gtgatcagaa gctccggaat atgggcaagg tcagcctggt atccttcaag cttcagtttc 3467101 ttcgtctccg actcaacccg ctgcttccca ttcgacatca caatgtaata ctcaagctcg 3467161 ctgttccaaa tcaaacgttt cggaatttgt gccaaaaact tgcggaccgc tccgggggtc 3467221 gggtccatcg gcaccatttt gtagcccagc tcattacttt gtttataaaa aagaaaggcg 3467281 gaaaatgctt gatacgaatt atcgcgaact tgagcctcaa tcattagatt gcttctcatt 3467341 tcagctttca catcaatttg aggaggattt tcaagcaagg gtatgtaatg aggcgtttga 3467401 aatagttcct gctgtacaac aggaaaagct ttcgattcat gatggccgcc agacaaaacg 3467461 gaaagaaaag acagtaatat agaagcaata accgtgtatt tcctcatcaa agcacctccc 3467521 ttttcatgta ttttgcgtct gaacagggaa gcttatgagt tcatttttgt gcataaagaa 3467581 caaaaaaacg tctgtctctt gaaaattcca ctattaccca gtaaactaag gatagttaac 3467641 cagttaacaa ttaaatcaga gaggcaaatt gatggacaac agcattcatg atgaattatt 3467701 tcaagctata caacaattcg cattaaaaag ggataaacgc gtctggcaaa aggtgcagat 3467761 accatccatt ggcatatcct cacaacatca cgatcacctc aaaaaagact ggactttgac 3467821 ccagcttcac attgtttcct gcatacatac cagccaaaat gtgaacaaca gcttcttagc 3467881 atcccgttta cacatctcaa aagccgctgt ttcaaaagcg gttcatgctt tgttgaaaca 3467941 caatatcatt acagtgacaa aaaagcctgg caacaaaaaa gaaatttttt atacgctaac 3468001 tgatagcggc agaaaattgg cggcattaca tgaacagctt catgagaaag caaaggagca 3468061 atataaacag cttttcaatg aattttcaat tgatgattta aaaacagtga ctgcgttttt 3468121 caacttgtgg atcaaatata tgtaaaaaga gtctcacccg catgggagag acctttggaa 3468181 ttctattatg ccccgtcaaa cgcaacgaga agtgaaacag gtccgcgtgt atacagaccg 3468241 gactcagcat aacaaaaatc ttcctctaat ctgatattcc gcatcttatc cagcacaata 3468301 ttagctacaa tttcgatttc gtttttggca aaagctgctc ctacacagtt atgaatgccg 3468361 gatccgaaag cgagatgccg ggcggcgccg ctaaaagcgc tcttgatacc aagatcttcc 3468421 cgatgaatat taaacacgtc aggctgttca aatgcttcag ggtcccggtt agccgcaccg 3468481 atcatacaaa aaacaatcgt atcttttttg atttccatac cgccgaccac tgtatcttgg 3468541 gacagctgcc gcggaatcag ctgaaccggc ggtttataac gcaatgtctc cgcaatggct 3468601 ctcggaacta acgaacggtc agccaaaaca tcattcatct gctcaggatt gttgagcaaa 3468661 tggtagatca tcagtgccag cgtcttatca gccggttccg ttgcggctaa cagcacatta 3468721 agaatcagtg cgagtatatc cttgtccgac agcgccatgc cttcatattc agaagtacat 3468781 aggatcgaaa ttaaatctga tcccggattg acgcgacgtt ctttaatgac cggcatcaag 3468841 tattgggaaa gctgttcgct gcaccataac gaatgtgccc gcgcttcagg agattgagag 3468901 atactcgtga taaaatcggc aactccgctg tgccactcag agattttttc atggtctctt 3468961 ttatccagcc cgagcatgtc catcgtgacg cacaccgcaa acgtctttcc aaaatcattg 3469021 acgagatcac ttttccctct ttcaagataa ggcgctaaca agttttctgc attttgttta 3469081 atcaatggag acagatgatc cagtgcgtca ccgataaagc ttctcactac aattcttctt 3469141 ttggcagagt gttcttttcc atgcatttgg gccagcacag ggcctcgcat gactggttcg 3469201 gcacgctcaa caagtgattt cgtcgtgaag atatccggat gctgaaggat atagcggaca 3469261 tcatgatagc ggctgataaa ataactgtct atcgactctt cataatgaac cggatcttcc 3469321 tcccgcagtt gtgaaaaata agcatatgga ttgttttgaa attgatcaga aagcacacta 3469381 aacaatttaa tcgattggct catgttttac tccccctatc atccttcaga tgtgatccgt 3469441 ttctcagaaa gcatctgcgc catttcctgt acaatgagat acccttgatt cggccgcata 3469501 caaatagaaa attcatggtt actgatcttc tcacccagct tccacggacg atgataagca 3469561 aggagtgtct cttccacctc taaaatatcc ggagctccga taaaaaacgg cagctcagct 3469621 atgacatatt ccacagccaa attcagcata tcctcactga cttcttccat catcaaactg 3469681 acgccccgcg cacgcccgat tatcgcttca cgagacatgt ccaaacaagc atgtcgaaaa 3469741 tgaggctgct caaaaaatgc atgttcaact tcttgtctca acagctggta ggctttgtta 3469801 tctataaaat cagaaaatgt atgaatcgcc ttcggatccc cgccatgagc cacaagggct 3469861 ctttctgcaa atctcctgtt tcgtgatacc tctttcctta cttttcgttc agcctttcct 3469921 ctcggagttc caagcgcttc tagaagatta gccgcctcat gccctgcaag taaaactgaa 3469981 acgcttttaa attgagcttt cgcccatcca attaatctgt aaatataatc ctctgaaaac 3470041 ctgctgttaa atgggctgat ccccaccaaa acatgcctgc gccgttcaaa tatttctctg 3470101 cagttttctg ttaatgcctc agcaataaaa tgcacagacc ttctttccgt taccattccg 3470161 gtcatctcat tcacccctaa aacttatccc gctttaagtc atcaccctca aatacaagat 3470221 ggaatagcta gaacaactga acaagacgaa tggcaggcat cacttaaagt ttccaaatgt 3470281 tttttaagat tttaataatc attttcaata cccatatcat gataaatgtt tactagtaaa 3470341 cattagtcat tttatccctt ttccttccaa acgtcaatat gatctgtgcc caaatatttg 3470401 aaaataaatg taaacatcac attttccaca cactttttac acgcatattc agcatgacat 3470461 atcaacaaat agtctaaaca ccaacaattg acaacgaaaa caagaaaaga taaaataaaa 3470521 ttgttcacca gtaaacgatt tgttttattg tttcatcgta aactattatt cctaagaaag 3470581 aaggtagcct atgtctgatt tgacaaaaca gatgatatac gacatatacg tgagactgct 3470641 gcaccttaat gaacaaaaag cgaacacttc acttcagcaa ttttttaagg aggccgcaga 3470701 agaggatgta gctgaaattc ccaaaaatat gacaagcatt cacgtcattg actgcatcgg 3470761 ccagcatgaa cccattaata atgccggaat tgccagaaaa atgaacttat cgaaagcgaa 3470821 tgtaacgaaa atcagcacaa aactgatcaa ggaagaattc attaacagct atcagctgac 3470881 agataacaaa aaagaagttt attttaaatt aacccgtaaa ggcagacgga ttttcgactt 3470941 acatgagaaa ctgcataaaa aaaaggagct ggctttttac caattcctcg attcattttc 3471001 acaagaagaa caaaaggctg tattgaagtt tctagagcag ttgacgtcaa cacttgaagc 3471061 agaacaaacc gatgggactc cagacaaacc tgtaaagtaa acaaaaaggc ggtgtacact 3471121 ttggctcata caaaatcaaa ggcagtattg atcttataca ctgtttgctt cagtgcattt 3471181 tttgcatctt taagccagaa catttattca cctattcttc cgatcattaa agaatcattc 3471241 catgtttcca cagctatggt gaacctgtca gtctcagttt ttatgattgt gacagcaata 3471301 atgcaaatta tattaggagc gatcattgat tttaaaggcg ctcggatcgt cttgattacc 3471361 ggtattctgg caacggcagc agccagcatc ggctgtgcgg tgactactga ctttaccttg 3471421 tttctgatat tcagaatgat acaggcagcc ggttccgcag cactgcctct tattgctgcc 3471481 acaacgatcg gacagctgtt tacaggaaat gaacgcggga gtgcaatggg aacgtatcaa 3471541 atgctcctgt ctgtcgcacc ggctattgct ccagttctag gaggattcat aggcggagca 3471601 gccggatacg aagggatttt ttggatactt gcggccatct ctatcgtttt gctggtgaca 3471661 aacagcatca cctttcctaa agattctcca actgaatcta tgcagcaagc caaaggcaat 3471721 gtgttcgctc attataaatc aatatttaca aatcgaacag ggaacgtcat tttgacttta 3471781 agttttgttc tctttttcat ttattttgca gtaattgtct acctcccaat attgctgaca 3471841 gagcattacc atatagatgt gggtatagca ggactgttat atttgccgct ggcgctgagc 3471901 acgattgcag gtacgtttct gtttaaaaga atacaggcaa aaatcgggct gcacaccttg 3471961 tttatcggaa gcaatgtgat tgccgcctgc agcatcattt tatttgctgt tacacattcc 3472021 gtttctctcg ttctcatggc tctgacgctg gcactgtttg gcatctcgat gggggttatt 3472081 cctcccttgt actctacaat gattactaat gaatttgagc acaacagagg gagtgcaatc 3472141 ggaatgttta actttatccg atatacaggc atggcagcag gtccgatggt atctgcctac 3472201 ttgctcacaa tgatgccgtc tgccatgtcc tttagcctcc taggccttgg atttgccgca 3472261 ttgagctttt gccttcttcc gccaatgttt tcgccgcaga agcgcacgaa acaaaaaaag 3472321 caccacatgt aaaaaagctg cctttgcggg cagctttttt tatttttttc taagcggctc 3472381 taaaatgcct ttttgaatca gcaaatggaa gaccgacagg ataacggatg cccatatcgc 3472441 tgtgccgaag ccgtcgattt gaaagctgtc acccataatg gacgcggtca tcataagcgt 3472501 gatggcgtta atcacaaaca agaagagtcc aagcgtcacc atggtgaccg gcagtgtaaa 3472561 tataattaaa agcggtttaa tcagcacgtt taagatcgat aaaatgaggc tggcgataat 3472621 cgctgcccca atgctgctga tatggatgga gtcaatatat ccatcaatga cgattaataa 3472681 caatgcattg actaaaatgc tgactgccca ttttaccatg tcatttcata tccctttctg 3472741 acgggacgat aaaaatccaa atgatataaa tgagcaaaac cggcaagaca cttgtcataa 3472801 tggctaagat gacagttatg actctgagga gtgatgcgtc ccaattgaaa tattccgcga 3472861 gacctccgat aacaccggcg attttcttat ttttttctga gcgataaagc ttattcattc 3472921 gatcacctct gtgagtactt tagtttgatg gcgcctgtta gtgattctga gaagacggtg 3472981 atgttttgat catgtgcctg atttgaagtg aacatcattt ctttttgaat cgtatcattt 3473041 ttttccttca gcatctctac atccattaat tcatgggaca gcgtaccaag attgcttttc 3473101 agctctgcct tcactgcgag atcgtccgga attgcaagct ctacatttcc agtcgttgtt 3473161 tttgcataaa tggagcggca gtctgattct gttacgttaa tcgcaatatt tccgttaaag 3473221 ctttgaacgt caatggattc gcttttccct cggagatcga tcaatccgtt aatggtttcc 3473281 gcttctatcg taccgcagct gtggcttgcg agcttaattt gcccgttggc cgtttcagct 3473341 atggcttttt cggctgttaa atacgagaac gacagcacgc cgtttgtcgt tttcgctgag 3473401 aactctttta catgtaaatg ttcccctctg actggaccgt taaacagctt cacccgaatc 3473461 ttatcatact ccttctgagg aatatacaaa gtgacattcg ttttcatcgt ctttttctca 3473521 gtacggataa aaaacttatt acctttgatt tcacattcaa tatgctgaag aaatgcgtgt 3473581 ctcgccgcat cctggctgtc agcgcgatat accttcgcct ggcattccgc tctgatatcg 3473641 tcatcttccc aagggacgat atttacgctg ccattggcaa tttgcagctc aacactggaa 3473701 aagtcagtat ctttaaattg aaaaatgtgc tgaacatcat acgcatggcc aaagtttaaa 3473761 tcaaggtcaa cttccttgac ctttttcaca gcagaatcaa tccagtcaaa cagcttggct 3473821 cctaaagacg gtttgccgct ttcttttttt gccgttgtaa atggctcttc ctcgtcatga 3473881 acgtgaactg agagcgctgt gattttctct tctttttcct tgtagtcgct gtcaagcttt 3473941 tcaatcagtg tcaaagcttc ttgtgctgta agctttcctt cctcaacaag cttaaggatt 3474001 cgttcctttt cttgcttcat tacgatctcc tccccattgt ctacttatgc tgcacgcagg 3474061 accttaatgc cctgaatcac attccaaatg ataatgccaa tgacaactaa gaaataaata 3474121 accgctcccc cgatgattac aaatacagga agcaagctgt ctccatcaat cgcaacggct 3474181 ccgccaagta aagcaataaa aaggaacagc cagccgacaa acggaacaat gtgagaaata 3474241 agagagcgta tcgcatggcg ttttgtttct ttctcattta caacaaaata tgcgacaatc 3474301 ggcacaatga ttggcgcaat gaacacactg aaataacaaa gtgatgcaat aatagcttga 3474361 ttacggttca attcattcca cactcctatt gtgaattgtc catgacaaaa gatcagggac 3474421 gttttactta tttatacgtt taaaatctct tcaggtttca aattcattct ttagacatgc 3474481 tccgatttac ggaaattgga ttttaaaaag ttttagaagt agaatcttcc ggctataccg 3474541 attacaatat gtaaaaagct tacggcaacc aaggaggctg gacaagcaat ggagaaagat 3474601 cccagtgact atacagtaac acaagaatca gtgttaaagc tgattcagga acaaaaaaga 3474661 atgaatcgtg aaatgatcac cgagcttgag cagattcacg gacccttccc gatctctcac 3474721 gatatccaat atataaaagt gctgctcgac agcagcaaca cacatattgt tcaagattta 3474781 atgagtgtaa gtaagcagct gtataagaag actttgtaat tgcggaaaac atatcattca 3474841 ttataactga aacaaagcta aaggttagat gacaatatct tgcctttttt gttttgaaaa 3474901 aacaagtgat tccctggctg tcacaaaatg attgtaacaa aaaaagcctg ccggcacatc 3474961 cagttaatgg actctgtcgg caagctgtaa ctatcagaaa gagatagccg ttcaaaatta 3475021 acgtaacaat tgaagcacgt tttgcggctg ttggtttgct tgagcaagca tcgcttgaga 3475081 agcttgagaa ggaatgttgt tctttgtgaa ctcgctcatt tctttcgcca tgtcaacgtc 3475141 acggatacgg gactcagcag ctgtcaggtt ttcagaagaa gcaccaaggt tgttgattgt 3475201 gtgctctaga cggttttgta ccgcaccaag tttagcacgt tggtttgaga cattgttgat 3475261 tgcagtatca atactttcaa gttgtgtatc aaaaggagta ttagcaaaat ctgttacatt 3475321 aagtgcgttt actcctaaag cagttgatga catgctgtca atgttaactg taagctgctg 3475381 gccagcattt gctccaattt ggaaagtgaa accatcagtt tcagtaccat ctaataactt 3475441 tttgccgttg aattcagtac gatttgaaat gccatcaact tcctcaataa gcgcatccat 3475501 ttcatcttta attgcaccaa gatcttctgc ttgttgtgta cctgtgtttc ctgcttgaac 3475561 agtaagttca cttctaaacc tattatgccg taaagaaaaa gcttgcctgc taagcccaag 3475621 gatggacttg ccgacaagct gtcccctctt aacagagggt tttaagatgt agctgtttct 3475681 tttgctttca agagcgattt catgcgtgtt ttgtcacgtt cgataacagg ctttaaataa 3475741 cggcctgtat acgattcttc aacttcagtg atttcctcag gcgttccaga cgcgacaatg 3475801 gttccgcctc cggctccgcc ttccgggccc aaatccacaa tgtaatcggc cgtcttaatg 3475861 atatcaagat tgtgctcaat aaccagtaca gtgtctccgt tgtctaccaa ccgttgcagc 3475921 acgacaagaa gcctggcgat atcgtcgaca tgcaaacctg tcgtcggctc atctaaaatg 3475981 tagagcgtac gtccggttga gcgtttgtgc agctctgacg cgagcttcac gcgctgcgct 3476041 tctccgcctg acaaggtcgt cgccggctgg ccgagcgtaa tataacctaa accaacatca 3476101 taaagggttt ggagcttgcg tttgattttc gggatatttt caaagaaaga aagagcatct 3476161 tcaaccgtca tatcaagcac atcagagatg ctttttcctt tgtacgtcac ttcaagcgtt 3476221 tcacggttat agcgtttgcc gtgacacacc tcgcatggaa cgtatacgtc aggaaggaag 3476281 tgcatttcaa ttttaataat cccgtctccg cggcaggctt cacatcgtcc gcccttcacg 3476341 ttgaagctga aacggccttt tttatagccg cggaccttcg cttcatttgt ctgcgcgaat 3476401 acatcacgaa tgtcatcaaa tacaccggtg tatgtcgcag ggttggatct cggcgttctt 3476461 ccgattggcg cctggtcaat gtcaatgact ttatctaaat gatccaaacc tttaatctct 3476521 ttatggctgc cgggcttcgc tttcgcttta tgaagctttt gcgccagcgc cttatgcaaa 3476581 atttcattaa cgagtgtact ctttcctgaa ccggaaacac ctgtaactgc tgtaaacgtc 3476641 ccaagcggga acttggcatt cacttttttc aggttgtttt ctgatgcacc tttaatttca 3476701 atgtaacgtc cgtccggctt tcttctttca ggaggcaatg ggataaactt tttccctgat 3476761 aaatagctgc ccgttaatga atttggatct tccatcactt cttccggcgt acccgcagat 3476821 atcacctgtc cgccgtgaat gccggctccc ggtccaatat ctattaaata atctgctgcc 3476881 atcatcgtgt cctcatcatg ttcgacaaca atcagcgtgt tcccgaggtc tctcatattt 3476941 ttcagagcgc tgatcaagcg gtcgttatca cgctgatgca gaccgataga cggctcatct 3477001 aaaatataaa gcacaccgga taaacgcgag ccaatttgag tcgccagcct gatgcgctgc 3477061 gcctctcctc cggacaatgt acccgctgcc ctgctcaatg tcaggtaatc gaggccgact 3477121 ttgtccagaa agcttaagcg ctccacaatt tcgcgcaaaa tcaaattggc gatctgcata 3477181 tccttctcag aaagggtaag atctttaaag aaggcaagtg cgtcggcgac agacagctcg 3477241 gtaattttcc caatgtggcg gccgtcaatc agtacggcaa gcgcctcttt ctttaaccga 3477301 tagcctttgc acgtcggaca agacttctga gacatatact gctccatttg ctcacgtatg 3477361 aaatcggagc ctgtctcctt atagcgtctt tcaatgttgc gcaatacgcc ttcaaattga 3477421 atttcacctt cgcggatttg tccaaaatca ttttcatatc ggaaataaat caggtcatcc 3477481 ccgctgccgt acagcacttt atccagttga tgcttcggca aatctttgac cggcacatcc 3477541 atatcaatcc cgtagtgggt gcagactgcc tcaagcagct gaggataata ttgtgagctg 3477601 atcggtgtcc aaggggcgac cgcattctcc ttcaatgaca aatcttgatt ggggatgaca 3477661 agatcggcat ccacttcaag cttcattccg agaccgtcac acgtcggaca cgccccgaac 3477721 ggactgttaa acgaaaacag acgcggctca agctcaccaa ttgaaaatcc gcagtgcgga 3477781 caggcatgat gctcgctgaa catcagctct tcctcaccga tgacatcgat cataacccgt 3477841 ccttcaccta aacgaagcgc cgtttccaat gaatctgaca gccgggctgc cacgccttct 3477901 ttcacgacaa tccggtcaat gactacctca atggaatgct tcttgttctt ttctaattcg 3477961 atatcgtcgg aaagctcagc catctcgccg tcaattctga ctctgacata gccttgtttc 3478021 ctaatctgtt caagcacttt gacatgagcg ccttttcggc ccgagacaat cggcgccagc 3478081 acctgaagct tcgtccgttc cgggtattcc agaattctgt ccaccatttg ctcgatggtc 3478141 tgggatgtaa tctcaattcc gtgttccgga caatgaggct tccctactct cgcatataaa 3478201 agacgcagat aatcataaat ctcagttacc gtaccgacag tagacctcgg attgcggctc 3478261 gttgttttct gatcaatgct gatggcggga gagagcccct caattgcatc cacatccggc 3478321 ttatccattt gccctaaaaa ctggcgggca taggcagaca gcgactcgac ataccgtctc 3478381 tgtccttcag catatatcgt gtcaaaggca agggaggatt tacctgatcc ggacaaaccc 3478441 gtgacaacga caagctgatc tctcggaatc gttacatcta tatttttcag gttatgcgcc 3478501 ctggctccct tcacctctat ccgatccata gccatttgtt catcatcctt ccgcttttag 3478561 ctctaaaagt aaatcgcgaa gctccgcggc tctctcaaag tcaagcgcct tggcggcttc 3478621 cttcatttca tgctccatct gttcaacgac tttctggcgt tctttcttcg tcattttcga 3478681 cagcttcggc gcggcttttg ttttgtattc cgctttatcc tcagctgcta ctgtggcacg 3478741 aatgacatcg cgaatttctt tatttatcgt tttcggcgta atgccgtgct cttcgttaaa 3478801 ccgctcctgc tgctcgcggc ggcgttttgt ttcattaatc gcaatttcca tagacttcgt 3478861 tattttatcg gcgtacataa tgacgcggcc ttccgcattt ctcgctgccc gtccgatggt 3478921 ctggatcagc gaccgctccg aacgaaggaa accttcctta tccgcatcca aaatcgcaac 3478981 aagggatact tcgggaatgt ccaaaccttc cctcagcagg ttgatgccga caagcacatc 3479041 gtacttgcca aggcgcaggt cgcggataat ttcaatccgt tcaagcgtct tgatctcaga 3479101 atgcagatag tttactttaa tgccgatttc ctttaaataa tcggtcagat cctctgacat 3479161 cttcttcgtc aaagttgtca caagcacccg ttcattccgc tcgattcttg cttgaatttc 3479221 gccgatcaag tcgtcaatct gaccttcgat tggacggacg tcaataagcg ggtcaagaag 3479281 ccccgtcgga cgaatgatct gttcgaccat ttcatctgta tgttcaatct cgtacggccc 3479341 tggtgttgct gatacataca cgatattgtg catatgcttt tcaaattcct caaaacgaag 3479401 cggacggtta tcaagcgctg atggaagccg gaagccgtga tccacgagca cctgtttccg 3479461 cgcctggtct ccgttaaaca tgccgcgcac ctgaggaatt gtcacatgcg actcatccac 3479521 cacgatcata aaatcgtctg ggaaataatc aagaagcgta tacggcgttg aacctggagg 3479581 ccgcagagtc aaatgtcttg aatagttctc gatgccggag cagaaaccca tttcacgcat 3479641 catttcaaga tcatatcttg tccgctgctc taaacgctgc gcttcaagga gctttccgtt 3479701 ttcatgcatg accttcagct gctcctcaag ctccttctcg atattttgaa tcgccttctc 3479761 cattttctcg gcccgcgtta cgaagtggga tgccgggaaa atcgcaacat gatctcggtc 3479821 gccgagaatt tctcctgtca gcgcatctac ttcccgaatc cgttcgattt cgtcaccgaa 3479881 aaattcaact ctgacacaat gctcatcacg ggatgccgga aagatttcca ctacatcccc 3479941 gcgcacacga aatgtaccgc gctgaaagtc gatatcgttg cgggcatatt ggatgtctac 3480001 aagttttctg agcagctcgt tgcgctcaat ttccatttca gtccgcagtg acacgaccat 3480061 ttcccggtat tcctcaggcg aaccgaggcc gtatatacaa gacacactcg caataataat 3480121 gacatctctg cgctcaaaca aagctgatgt ggcggagtgt ctcagtttat caatttcatc 3480181 attaatacta gcgtctttct ctataaatgt atccgtttga ggcacatacg cctccggctg 3480241 ataataatca tagtagctga caaaatactc gacagcattg ttcggaaaaa attccttgaa 3480301 ctcactgtaa agctgtccag caagggtttt gttatgggca atcacgagag tcggcttatt 3480361 gacttcttta atcaaattgg acaccgtaaa tgttttccca gttcctgttg cacccagcag 3480421 agtctgatgc ttcttgccct cctgaattcc tttcacaagc ttttcaatgg ctttcggctg 3480481 atctccctgg ggctgatatt tcgagactaa ctcaaagcga tctttcacaa aaataagcct 3480541 ccgtttcttt aacgaaatct tcctatagat atagtaacac aatggaaagc aaaatcacta 3480601 aaaatacgaa ctaaagttcg gtggtttttt atttccagct gtttttgtgt ataaaaaacc 3480661 tgcttttaaa acgtaaaagc aggtattcag tctttatatt cattatgtcc gatttattct 3480721 tcttttttct ctgcagcttt tttggccata tacagtccgc cagccacaag agacacaaca 3480781 tccaatccta caataaaata cgtttctgta tagcctttta aataagaggc aaacagcaat 3480841 gcagctgtta aagcgatcgc cacataatga ttaaaggtga ctctagtaaa tagaacaaca 3480901 agcataaaag ggaaaaacaa tgcaaaaacg gcttttgtaa tcaacaaaaa ccctcctcag 3480961 ggattcttca tctgatctga ttatagtaaa aaatgaagaa tcggacaatc gtgcattcgc 3481021 tccctctact tacaccatac cccttttcag ccaaaatcaa tcaccatatt tgcattttgg 3481081 tgccggtcaa aacttattcc atggtgccgc tgttctaatc agcggcactt tttttattac 3481141 atcatcaagt ccgccgccag attccgagaa taaaagaaaa taggcataca gtaccagtac 3481201 ggccgcattt ttcaggataa tataaccaac ttaactattc attttattta ggactttctg 3481261 cgtttgacag cattttcctg aaaacctaca attaaatgat agtgtttact atcatttttt 3481321 aaacacaggc tccgcaataa aaagactaga gagaaaaaca aaatgaatga agaaaagagg 3481381 ggtttcaaat atgtattctg ttttatttcg ccaggcagaa gagtccagcc agctggctgg 3481441 agcaaaagga atgaatttga ttaaattgac caaacacggt cttcctgttc cggacgggtt 3481501 tattattcaa acgaatgcgc tcgcacgttt tatggaggac aaccagcttc aagagactag 3481561 tgaaaacgtc gaaggcggga tcatttccgg aacattttcg gatgagctga aagatgagct 3481621 gactagttcc ttttataagc ttagagaatc atatcgatcc gtagccgtgc gttcttcgtc 3481681 tgcttcggaa gatttagaag gcgcctcatt cgcgggtcaa tatgaaacct acttaaatat 3481741 caaaacagag gaagagtttc tggctaaagt gaaagaatgc tgggcctcat ttttttctgg 3481801 gcgggtcagc agctataaga aaaaaatgaa caatcaaatc gcagagccgt taatgggaat 3481861 agtcgttcag gggctgatcg attcagaaat gtcaggtgtt atcttcagcc gcaaccctgt 3481921 tacccatgat gatagagagc ttttaatcag cgccagctac gggttgggtg aagctgttgt 3481981 ttcaggaaat gttaccccag acacgttcat tgttaataaa tcttcgtttg agattcagaa 3482041 agaaataggt gcaaaggaaa tctacatgga gtctgcggca gaaggaattg ctgaaaaaga 3482101 aacgagtgaa gacatgcgca gccgtttttg ccttacagat gaacaagtga ttgaattggc 3482161 tgaaatcaca aaaaaaaccg aagacctgta cggatatcct gttgatatag aatttggaat 3482221 tgctgatcat caaatatacc ttctgcaagc tcgcccgatt acaaccattg atcaggacaa 3482281 aaaagcggca gaagaaaaac gcagcttcat gattaccgac actgatatga atgatttctg 3482341 gcttaacatg gagtctaata ttgaaggtcc ggtgagtccg ttattttcat ccttcatcgt 3482401 gccggcattg gaatatggct tgaagaagag catgcaaaag tttccgattg gtgtagttgt 3482461 tgatgaagta aaactttatc gcggacatat ttattccaaa aaccaaggcg gacagcagcc 3482521 tccttctgaa gactgcggca aagagctttt cccgatttta tcggagcata tgtatgacat 3482581 catcaatcac acatacctcc ctttttaccg gacactggac cagctcgcac aaactgagca 3482641 taccgcagaa agcgcactgg aagcttttca aaaactaaag gccttttatc tcacggctta 3482701 tgaagagcac tttaatatcg ttttcccgca aatcctttta acaaacaaac tgcaagcgat 3482761 gtatcaggac attcaaggag agtccgaaaa cgctcatttt tacgagatgc tgacaggaaa 3482821 aatgaacaaa tcactggaaa cggaccgttg cttatggcta ttttctgtgg aagttcagga 3482881 gaacccgaac cttctggcca tttttgaaaa caacaagcct gaacagctcc aggagaaatt 3482941 ggaacaaaca gatgagggaa gacacttcct gaagaacgtc catgaattct tgcaagaata 3483001 cggatggaga tctgttaaaa gtcatgatct gattgaacaa atctgggtgg aaaatccgta 3483061 tttcgctctg gccaatattc aaaattatgt ccgtaatggc tatcattttg acaatgaatt 3483121 tcagaaaaca aaagaaaaac gagagaaatt atacaatgaa ttcttggaaa gcatagaaga 3483181 tcccggttta cgcaccgaat ttgaccgcta ttatcaatgg acactgaact ctgcaaatat 3483241 aaaagatgat caccactttt atattgacgc catgctggat gccaaggcga gaatctttct 3483301 gctgaagata ggtgaattgc tggcggaaaa cggtgtcatt caagatcggg aggacctttg 3483361 gttcttatat gacgacgaag tggaacaagc gcttcttcac cctgtatccc tgcaagaaaa 3483421 ggctgaaaaa cgcagacaga tttttcatga gtatgagctg gcccaagccc cggcctacct 3483481 cggcaccccg acaaaagaac agctcaaagc agctgaagaa attgtcggcg ctgtgataga 3483541 ggatgaaaaa aacacagaga atcatatttt tggcattgcg gcatcaagcg gcattgcgac 3483601 aggtccggtg aaaatcattc gggacgccaa tgaattttct caattcgcgc ctggagacgt 3483661 actcgtttgc aagatgacca caccgctatg gaccagcctg tttcaagacg ccaaagcgat 3483721 tattacagac acaggcggca ttttgtctca cgctgcgatt attgcccgtg aatacggcat 3483781 tccagccgtt ctcggcacac gcacggcaac cgaaagactg cgagacggtg acatcatcac 3483841 tgttgacgga agcagcggca aaatcacagt tgtcagccgg tcctgatgcg tccccctctt 3483901 tcttatacaa gcggggcggg tgtatacttg tcctgccagt atattcgtga ggtgaaacgt 3483961 attgagaccg acaaacaaga gaatccttga tgctgccatg cagctgctcg tcaaaaaagg 3484021 atatcgcgca acgactacaa aagaaattgc agaaaaagca aatgtaagtg aagcgacgat 3484081 tttcaggaac tttaaaaaca aacaaggact agttgaggct ttgctttctc agcattcttc 3484141 aaacagaggc agcattttgg aacaaacaga aggggatttg tacaaagacc tgcttcatat 3484201 cggaacctgt ctcttggagg agctcgaaca tagaaaagat atcattaaaa tcagctttcg 3484261 tgaaccggcc atgtttcagg atgtcattaa ccacgtcact gaatatcccc aatctatgaa 3484321 acagctattg gttgattatc tcaaaacgat gggtgagaaa ggggttattc agacaggaaa 3484381 tgaagcggaa catgccgacg tgttcatgtc gattatcttc ggttatttca ttcaccgtct 3484441 ccacttagga gaccgggtca tatcaatgcc ccaggaaaaa atgctggagc atagcacagc 3484501 tctatttgtc aaaggaattt ctgctgatta actccttggc ataataaaaa ggaggatccc 3484561 aatgagctca agaaaagaat gggcgctgat cgtctcgcta ttattggggg ccattctggt 3484621 tcccattaac tcaacgatga tcgcggtcgc gctctcatct atttcccata cgtataacga 3484681 gtccatcgca agcatcactt gggtggttac cgtttattta atcgtgatgg cagtcacaca 3484741 gccgattgca ggaaagctcg gtgacatgta cggcaataaa acaatgtact tatggggagt 3484801 cggccttttt ctaatcgcat ctctaggctg cgccctttca ccgagtctgc tcctgttaat 3484861 tgtctttcgg gcattgcagg ctgtcggcgg ggcattgctt acgccaaaca gcattgccat 3484921 tatccggcat gttgtttctg aaaaacgcct accgaaagtg tttggatttt tcggactggg 3484981 cgcgggactt ggtgcagcac tcgggccttt tatcggctct atactgattg acagcttcag 3485041 ctggcattcg attttttggg tcaacatccc gttcctcgcc attgctttat ttacggcatt 3485101 aacgatgttt cctcaatata aagaaaataa atctgacgcg ccgctggata tcatcggctc 3485161 tctcttgctt gcaggcagca tcgtttccat tatcctgctg acgaaaaatg aggctccatg 3485221 gggatatact gtatacagtg tattgatact tctttttgtt ccgctttttt tcagaagaga 3485281 aaaacgtacc cagcacccca tcattgactt tgcactgttt aaaagctcaa cctttacaaa 3485341 tgcgaatcta tcagtcttgt taagcaattt gatgatgtat gccgtcttat tgattatgcc 3485401 gttatttatg acgaaccaat ttgggcttaa tacatctaac agcgggatgg cgctttctgt 3485461 attttcgatc ttcatgtcag ccagcaactg ggtgggcgcg cagctccatc acaaatgggg 3485521 agccaaaaaa atcatttttc tttcatttgc catgatggct ggtgcgaatc tattattttt 3485581 gctgttaagc agctcgcatt ctgtcttgtt cctcatgctc tctcttatcc ttggcgggct 3485641 cgcttccgga gtcggtctga ccagcatgca ggtttcatcc cttgccacag tagaccccgg 3485701 tatgtcagga gtggcatctg ggattttctc gaccttccgt tatttcggaa gcatcatttc 3485761 atcagcctta attggcctga tttcgggata tcacacccta tttatgattc tctttgctgt 3485821 atccatcatc ggcgtttttg tttcattggg catcaaatct gatgaaacgg cacggataga 3485881 aaaaaactca gcgtaacaca aaacagcccg gcatcgcatc atcctgcggt gccgggctgc 3485941 cttttatgat cccgaagcga ctgcttcgtc ttcacggtca tcctttacga agaggatgcc 3486001 caattcatga tgttctcctt cataagaagc tcgctggtca aaacgaattt ctccattcaa 3486061 accgataatt tcaagcttta catatgcacg gttatgctga agcgcttcat agaaatcaga 3486121 aacgttctta accggtatgc cattgacttt cgttatgatt tccccgattt tcaattccag 3486181 atcctcagcc ggcgtattgg ggataatccc aagcaccatt aagccctgat cccttttcga 3486241 gaaataaaac ggagccgcgt tatcattcac tctttgcttt atggacagaa aaatacgccc 3486301 taacaaagcg gtacagaccg ctgcacccgc aagcggcgtc cacagtaagc tcgctgcacc 3486361 gagaactgcg acggcaagac cgagaataca aacgcgtttc gctgtgatcc ttatactcgt 3486421 ttcaggcagc gatccctgta ccctttgtcc aaatccgaca aagtaaggaa tccatagaaa 3486481 atggaatgag ccgccgggaa ccgtaaacac gggccaccag ctaaggtgcg attctaaacc 3486541 attaccgggc acgagaagga acagcggcaa aagccaaacc cggtttgcca gctgctgtcc 3486601 gatcggcaaa ccgcggctgc ttacgacaag tgccggtgat gttctcacat gcgcagaacg 3486661 ataagcaacc gctccttcag tgataatcag caaacctaga aacacagcca cagccggcca 3486721 aacaactgca aatccttgcg gaaatctctc cagaaagggc tccgcctgat atatttgcag 3486781 tccaaaacct atcagcatac tcacactgac gatatatgca gcagacatcc agtttgcgcg 3486841 aagagtgaac gctgccgctg cagtgataac ggcaataatc gcaagtaaac cgagaggaat 3486901 cgatattccg agtccaccta aaataactga caaaagaaga cctggaatca gtccctttgt 3486961 atatgtaaat ttcagatcat cataaatatc tgctattctt gtatgaaagg tttttcgttc 3487021 ccgtttgatt cttacatagc cgaaagccaa ggttatgatg ataaaaaacc agaaaagcgg 3487081 gtgtaagaag aacaagcccg cgctttttaa cagttcaatt ccccattgaa cagacactat 3487141 ctctcaccgc ctcaagccaa acatgttact catattctat caaatattaa atggcttgga 3487201 tatcctcagg agagtttatc tctcttgcgt catccacagc gtgacattcg atagtgaaaa 3487261 atcctttaaa tagtggttta catccacatc caataacccg ctgattagat gcatcgacct 3487321 ttttatatct gtcagattaa ttcctaatcg cttatggttt ttcattaagt agttaaaata 3487381 atgtttggcg cattcctcat taatgtcatt tactgattcg acattggtgt aattgaccaa 3487441 atatctgctg aacagcataa gaagacttag tgcttttgta gctgaaaatg ttacgtcttg 3487501 tgttctgtct tttaattgtt ccactaattc ataatatttt tttttcacgc acaatacttg 3487561 ccctcttcaa ttgtgaaccc ccattttctt tatacagata agcacgggcc agtataagca 3487621 gcagtactgg agtgctaaca agcattctcg ctaacgttac tctttaaata cctgtcgttc 3487681 agctgccatt aacctgatta ctgttctttt tagaaccttc ttatattgta tgaagtaaac 3487741 aaagactagg caacttgcaa aagtttcatt ttaaatgcat attaactcgt tagaaagtct 3487801 ctctcatata ttgatatcgg gtaataacag tcctttataa atgtttattt gtgaaaattt 3487861 ttttaatttc ttgtcaaaaa ctcatttttt atgtgactta tgatccataa tctctttaag 3487921 cacaaagaaa caggagatga aataccatct cctttaattg acaaataatg atttcaatgc 3487981 tgtttgaagc tgcaaatcat ttttttcatc tgattttttc ttttctatct gctgatttaa 3488041 tgtctctgca gtgcgagtgt cgatcacacc ggttttattc agcttgtttt gatcctgaaa 3488101 agccataacc gcttttttca tgtctttgct gaaatagcca tcctcacgtc ccggatcaaa 3488161 gctgagacct tttaacaata cctgcgcatg cttgacgtct tcattgttca tgtccacttt 3488221 aagcggctct ttcagctgta agggcccggc ggaaaaataa tcgggctgct taatcgcaat 3488281 ggtcggttca attcctttct tatgaatcca gtttccattt ggcgtcagcc acttgtaaag 3488341 cgttaatttg atgttgctgc cgtcccccat tggcacagcc tgttgaaccg ttccctttcc 3488401 aaaagacgta tcgcctacaa catcataatg gccagcttcc tttaatgcgc cggcaagaat 3488461 ttctgatgca gaggcacttc ctttatccgt aatcacattg acagggtacg cttttttatg 3488521 ggtcaatgtt gaaaaataac gttttttatc tccattgcgt tcagcaatct gaatatacgg 3488581 ctgatccttt gtaacgaaat gcttaagaat ttcttccaca ctttgaagat atccacccgg 3488641 gttgccgcgt acatcaatga caagtccttc tatttctttt ttctcaagct ccctcagcgc 3488701 ttttgcaaaa tcctctgcgg tgtgctcaga aaaagtagag atggcaatat atccgacaga 3488761 atgcccctgt acttttttct ctgatgcaaa aaccgtttcg agcggaatct cagctctctt 3488821 gatccggaat gacaactgct tcttcgttcc aggccgctga atcttcattg aaacgctgga 3488881 cccttttttt cctcttattt ttaacacagc gtggtttaaa tccttgccgg ccatcgattc 3488941 tccattgatg ctgataattt catcattagg cttcaacccg gctttttccg ctggcgattt 3489001 cttgaatgga gaaacaataa taattttgcc gtcttccatt ccaacctcag ccccgatgcc 3489061 ttcaaatgag gaatcaagag aatcagaaaa ttgcttagct gtctgcttgt ccatgtaaac 3489121 agaataagga tcatttagcg tagacagcat tccctggatg gctccctcga gcagcttttc 3489181 tctatctact ttttctacgt actcattcga aattaactca tacgcttttt cgattttgtc 3489241 catagcttta tcccgttcag agtcagcttg tgccgtcgcg ggaactgctg cagtctgggg 3489301 cttatccatc tcaagcaggt tgattcccgc atatacaccg gcgcctccga acagcatgct 3489361 ccctgctgct atcacagcca ttattttttg attcatcctt tactcctcct gtatgccaga 3489421 ctgtctttac caaaacctag agatagtata tgtaaaggat ggagatttca tgtaatcata 3489481 gaagaaaaag aaggcaaatg aaaagccgtc ccgaaaacgg aacggctttt tcactttata 3489541 ctcgcagaaa cttgcggatg gaagtcagac ttccccatac tccaattact gcgccgattg 3489601 caatcagcac tagcgaaact tggaatacaa atggattata aggaagaaga gagacaaatg 3489661 atccttgaac ctttggaacg acccatccga tgacgtattg gtaagtgctc agcaccagtg 3489721 caatcggaat cacagaaccg aatacgccta gcagcaatcc ttcaaggaaa aacggccagc 3489781 ggataaacca gtttgtcgcg ccgacaagct tcatgatttc aatttctttt cttcttgcga 3489841 aaattgtaat tttaatggtg ttggaaatta agaacatcgc cgtaaatacc aggccgataa 3489901 ttaacgcgat tccgatgttg cgggaaacgc cgaccacttt aaacaaacgg ctgacctctt 3489961 cttttccata agtgacttta taaacatgat ccattttttc gatctttttc gccacgttcg 3490021 gcgtatcatg cggatctgtc gttttgacga caaacgcatc attaagcggg ttttcctgat 3490081 ccttcattgt cagggatttt ccgctgtcac caaaactgtc aaccagctgg tcaagctctt 3490141 tttctttaga tgaaaaagtg acactctgaa tgcccttcag ttccttaata tcgttctgaa 3490201 gcttgtcctg tgccttctga tctgcagtca gatcaatcag cactttgatt tcgacttgtt 3490261 tttctgcatt cgtggccatg ttattcaaat tcagcataat cactaaaaac acgccgacta 3490321 aaatcagcgt aacggttaca gcactaatgg atgcaaatgt catccatgtg tttctcccga 3490381 gagatttaaa actctcacgc aagtggcgcc cgagaatttt aatcatatga accatactcc 3490441 cctcttgact catcacgcac aatgatacca tcttcgattg caatgacacg tttcttcatg 3490501 gtgtttacga tttctttatt atgtgtcgcc atcacgactg ttgtcccgcg gttgttaatt 3490561 tcctccagcg tcttcatgac ttcccaggac gtatccggat caaggtttcc tgtcggttca 3490621 tcagcaatga caacatcagg gttgttcaca attgatctgg caatagatac acgctgctgc 3490681 tccccgcctg aaagctggtc aggaaattgt cgcgctttat gcttcagctg cacgagatca 3490741 agcacttcaa gcacccgttt cttaatgaca gacggctgtt ctccaatcac ttcaagggca 3490801 aatgccacat tttcaaaaac agtaagtttc ggaagaagct tgaaatcctg aaagacaaca 3490861 cctattttgc ggcgcacgaa aggaatctct ttttctttaa ttgtcgcgag atctttatga 3490921 ttgattaaaa tttgtccttt tgtcggtttt tcttctctgt aaatcatttt aataaaagta 3490981 gatttacctg ctccgctcgg accaacaaca tacacaaact cgccgggatg aatggtaaca 3491041 gaaatcccat tgagtgcttt tacgccgttc ggataggctt tatatacttc cttcatctct 3491101 atcatgaaat cacctaatct tttatatcat tttatctatc acacggtcat actcttcgaa 3491161 tgcattcgac aatttatgac ccattcattt gtaaaaagat gaaaaatctg aaagttccct 3491221 ttttcaatac acttcattat acgtcaaatt tagacataat actattacag tttcttttca 3491281 ttcatattgt caaggcataa aaacatcctt gccagcactc ggcaaggatg tttttatctt 3491341 actttttttc tgacagccat ttggcaataa cagcggcttc gttatcatct acaagcccct 3491401 ttggcatatt gccgcggccg tttttaataa tgctttcaat tttgtgttca tcgtatttgc 3491461 ctccgacctc ttggagatta ggccctgaca caccttctaa atccttgccg tggcagccta 3491521 cgcagctttg ctgatataat tcttcccctt cagatgcagt ggcttccgtc ttgctgccag 3491581 tgtctgtctt ctcttctttt gcatcgtttg atccgcaggc agccaacaga acagaaagcg 3491641 caaatccaat cattagtatc gataactttg atttcatgtt gagaagcaca actcctttac 3491701 gatctcttcc atattataac ctcgtttaag cgcgtttgaa accctcgccc agcacctcgc 3491761 tcgcgtctgc tacaattaca aaagctgact catcaatctg tttgacgatt tgtttcaatt 3491821 tggtgaattc agtttgccca accacgcaca ttaaaatcgg acggtcatcg tcagtatatc 3491881 cgccgactgc agaaattttt gtcacgcctc tgtcaatctt ctgtaagaca gcctccttga 3491941 cagcctgctc ctgctttgta atgatgagcg ccatttttga acgattaaag ccgacttgca 3492001 caacatcaat ggttttgctg gacacataga cgccaagcat ggcatataag ccttgctcaa 3492061 tattaaatac aatcatagcc gtaacaacga tcattccgtc aatgatggcg agacacttcc 3492121 ccaatgacag accggagtac ttatgaatga tctgtgcagc caaggctgta cctcccgtcg 3492181 aacctttccc taagtacaca ataccaattc cgatacctat cccgacaccg ccaaaaatcg 3492241 ccgccaggag ttcatgatga gtggcgggct gaatatccct tgtcagaaac actactagcg 3492301 gcaaaaacac agaacctgca agcgtcttta gtccaaattt cccgccgagc aaaatgacgc 3492361 cagcaataaa taaagggata ttaataatcc actgtacata cgctgcttca aaaccatatg 3492421 attgtaaaat cgtactgatc ccgctgaccc cgccggcggc aatcttattc ggaagcaaaa 3492481 atacattaaa ggacacggcc gtaatcgctg ctcctatcaa tatgtataca taatcccgca 3492541 aaatccacaa tgttttattc cgtacgtcca tcatatatcc tccgtttctt ccaatgctct 3492601 ccgatagcat tttaatcctt ccctgattag atgtaaataa cacccaaata cagtggtaat 3492661 atgctaaagc agcagtgaaa tcaaggatat aagaaataaa aaaacacacc cgtatgcatc 3492721 aggtgtgttt ttcagcttat gaaagcttag aacgcaggta ggcatcaata aacgtatcaa 3492781 tgtcaccatc cattacagct tgaacgttcc ccatttctgt attggtccga tggtctttta 3492841 ccatggaata cggatggaat acataagaac ggatttggct gccccagccg atttcttttt 3492901 gttcaccgcg aatttcatcc agctctgcct gctgctcttc aattctgcgc tgatacagct 3492961 tggccttcag cattttcatg gctctttcac ggtttttaat ttgtgagcgc tccgtttggc 3493021 atgtcacaac tacgttcgtc ggcaagtgag taatccgaac ggctgaatcc gtcgtattga 3493081 cgtgctgtcc gcccgcgccg cttgcacggt acgtgtcaac tttaatatcc tccgtacgaa 3493141 tatcaatatc aatttcatcg ttaaattcag gcatgacttc acatgaaacg aaagatgtgt 3493201 ggcggcggcc tgatgaatca aatggtgaga tccgcacaag acgatgaaca cctttttctg 3493261 ctttgagata cccgtaagcg ttgtgtcctt tgatgagcaa tgtcactgac ttgattcccg 3493321 cctcgtcacc tggaaggtaa tcgagagtct ctactttaaa gccgcggcgc tctccccatc 3493381 ttgtatacat tctaagaagc atagagcccc agtcctgtga ctctgtaccg ccagcaccag 3493441 ggtgcagttc taaaatcgcg ttatttttat catacggctc gctgagaaga agctgaagct 3493501 caaactcatt gaactctttt gttaatgact ttagttcttt ttcaagctca agctggagat 3493561 cagtgtccgg ctcttctttc aaaagatcat gagtcatttg taattcttcg tgggattcat 3493621 tcaatttttt atacgaattg acataatcct ttaaaccgtt tgcttcattt ataaccgttt 3493681 gagctttttg ctgatcattc cagaattccg gatcagccat ttgttcatct agctcagcaa 3493741 tgcgggcctc ctttgattcg aggtcaaaga gaccccctaa agtccgctaa acgagaagcc 3493801 atattttcga gctctgctct aatttctgat aattccattt cattcacctc attaaaagat 3493861 ccgcaggcgc ctgcaggcgc cgcggtcagt aaacttgccg gggcgaacta ttcagtacgg 3493921 ccgcagcaat ttttatattt tttcccgctt ccgcagtggc atggggcatt tcgtccgata 3493981 tcaaccactt tgcgaaccgg tgctttcttt gcttttttgt tatcgtcgcc ttcttgcggc 3494041 tgatgagctg ttgtttgacc ttgtacaacc tcttcacgct ccagattgtt ttcaatctca 3494101 gctttcatca caaattttgc gacttcgtcc tcaattgatt caatcatatg ctcaaacatc 3494161 gcaaaacctt ccatttgata ctcacgaagc gggttcgtct gcgcgtaagc acgaaggtga 3494221 atcccttggc ggagctgatc catcgcatca atatgatcca tccatttaga atcaacggca 3494281 cgaagaacga taactttttc gaattcgcgc atttgctctt tgccgaattg ctcttccttc 3494341 tcattatatt ttgtgatgat gcgatccata atgagctcaa gcatttcatc cggttctttg 3494401 ccgaagatat cgctcttctc aagtgcacct tcatcaagat aagttgtgtt gataagatca 3494461 actagaccgt caagcttcca ctcctcagga agctcttctc ttggcgtata ggctgcaatt 3494521 gcgcgttcga gagaagactt gatcatattt tcaacgattt cacgcaggtt ttcagagtca 3494581 atgacttcaa agcgctgctt ataaatgacc tcacgctgct ggcggagaac atcatcatat 3494641 tgcagaagct gtttacgcga atcgaagtta ttgccttcga cgcgtttttg agacgattca 3494701 accgcgcgag ataccatttt gctttggatt ggagtagagt cgtccatgcc gaagcggtca 3494761 agcatcgcca ttgtccgctc agctccgaat ctgcgcatca attcatcttc catagaaaga 3494821 taaaattgag taatccccgg gtctccctga cgtccggaac gacctcgaag ctgattgtca 3494881 atccggcgtg attcatgtcg ttctgttccg actacagcga gcccgccaag ctcttttaca 3494941 ccttcgccaa gcttaatgtc cgttccgcgc cccgccatgt tagtcgcaat cgtaactgcg 3495001 cctttttggc cggcctcttc aatgatctgc gcttcacgtt catggttttt ggcatttaac 3495061 acttgatgcg gaattccttt gtttttaagc agcttagaaa tcaattcaga tgtttcaacg 3495121 gcaaccgtac cgactagaac aggctgtccc gtcatgtaac gctgtgcgac atcctccgca 3495181 actgccttaa actttccttc catcgtgcgg taaattaaat ccgggcggtc atcacggaca 3495241 acaggcctgt tggtagggat cgtgacaacc tgcatgttgt agatgttgcg gaattcttct 3495301 tcctctgtct tagctgtacc cgtcataccg gcaagttttt cgtacattcg gaagtagttt 3495361 tggaacgtaa tcgtcgccaa ggtcatgctt tcgttttgaa tctcaagccc ttcctttgct 3495421 tcaatcgctt ggtgaagccc ctcactgtag cggcggcctt tcatcagacg tcccgtgaag 3495481 gaatcaacaa taacaacctg tccgtcttcc actacatagt caacgtcctt ttgcatcgca 3495541 acgtgagctt ttaaggcctg gttgatatgg tggttgagcg cgacatgctt cacatcaaag 3495601 aggttatcga tgccgaatgc tttttccgcc ttcgtcattc cttcttcagt aagctgtaca 3495661 gcttttgttt tgatatcgta cgtgtaatcc ttctccgctt ttaacgtgcg gacaaaagca 3495721 tttgcctgta cgtacagctt agtggatttt gcagcttgtc cagaaatgat aagcggtgtt 3495781 cttgcttcat caattaaaat agagtcaact tcatctatta ccgcaaaatg aagcgggcgc 3495841 tgaaccatct gctctttata aagaaccata ttgtcacgca aatagtcgaa gccaagctcg 3495901 ttgtttgtgg agtaagtaat atcagcggca taagcttccc gtttttcgtc ttttgacatt 3495961 gagtttaaat tcaaaccgac agtcaaaccg agaaactcga aaattttccc catttgctca 3496021 gcgtcacggc ttgccaagta ttcgttgaca gtcacgacgt gtacgccttt accggttaac 3496081 gcatttaaat aaacaggcag ggtagacgtt aatgttttcc cttcccctgt tttcatttcc 3496141 gctatatttc cgtcatgaag cgccacgccc cccatgagct ggactttaaa cggaaacatg 3496201 cctgttacgc ggcgtgaagc ttctcgaaca acagcgaaag cttcaacaag aagatcatcc 3496261 gttgtcgccc ctttttcaag acgctcttta aattcaattg ttttatgttt caatgcgtcg 3496321 tcagagagat tttcatagtc tccgcgaatc gcatcaatat cgttagcaat tttttcgtat 3496381 ctattcagcg tacgttttgt tggatcaaac attttattta aaattccaag catttataac 3496441 gctcctctat catcacacgc ctattttaga ggcatgtata aataatttac tagtccatgt 3496501 atacctctca ttatcatatc ataccttttg ttatttccaa agaatttgca aataagaaaa 3496561 acaaaaacct tccgcggaca tcacggaagg cttctcttca ttattcagtc ggttcaatta 3496621 agccatattt cccgtcattt ctgcggtaca cgacatttgt aaggtttgtt tccgcatttg 3496681 tgaaaacaaa gaaattatgg ccgagcatat tcatttgcaa gatcgcttct tcactatcca 3496741 tcggctttaa attaaagcgt ttctgacgga cgatgtccaa gctctcctcc tcttctatgt 3496801 catcctgaac cgcaatatct gtatcagagc caagaccgtt tgccaataaa tattttggag 3496861 agccctgctc acggaattta cggtttactt tcgttttatg cttacggatt tgacgttcca 3496921 gtttgtttgt tgcgagatca attgcgttgt acatatcctc gttatgcacc tcggaccgaa 3496981 gcgccagatc tgtcatcgga atcgtaacct caaccttaga ctccttgtca ttgtaaaact 3497041 tcaagttgac gttcacatca gcatccacgc tatggtcaaa atagcgctcc agcttgccga 3497101 tcttcctctc gacatgatcc tttaacgcgg gtgtcacttc aatattttct cctctgatgt 3497161 tatagttcat caaagaacgc ctccctttta ttaaggatat gtatctattt ctcttttacc 3497221 ctttacaatt cctgctgaaa cataaatctt ttgtgaaaat tcagtgaact ttgtcgaatt 3497281 ttgtttgtat ttgctctgtt attggcggtt cggaggtata tgtatatgct gattgaacga 3497341 aacaaatacc tcacacacgc ctaattgatt aaaaagggtt ccatacattg atgaatagac 3497401 agcatccatt ttctataatg aatcagaaaa tgttccttta aatactcaca gaactcatga 3497461 gagggaaaag agaaagagac caattgatca aactccgcaa aaatttggtc aaatgctttc 3497521 acacaaattt cagcacaccg cgaatccata atgaagagaa gtgttgaatg tgttgaatcc 3497581 aaataaaaaa aggcttggat cagatcttgg tagatccgat ccccttctgt ttttgataaa 3497641 ttctcttcag cctctatcaa ataacacaac ccctcttcga tggtaaaaag aagatgataa 3497701 taagctgata aaagcgtata atcttcaatg ctcttcaagg cactcaccta tttacgcttg 3497761 tcataatatg tgccgtcaat cgtaatgttg ttataagggt ttaaatacgt cgtatgcatc 3497821 acacgttttc ttttcatctg ctgaagttct gttgcgattg actgcttcag tctttccatt 3497881 tccttcacaa tcagctgatc ccatgtcaaa ataagtttca tctgctttcg ctcttcttct 3497941 gaaagcggca gagatatctc ctgaatcagt tcagaccgtg tagccacaaa gtcttcaatt 3498001 tgctttaaaa gttcatcgct ttccggcgta ttttgtatgt gtgacagcat actcttcgtc 3498061 tcagtgtata gttgatctat attattcatg cgatcccgcc tgatccgtgc cggtccttcc 3498121 gctcactttg aatggcttgt ttccaagcat cgcgaaaatc tgttacataa ccttcaacct 3498181 cagccagcat gcccgtatca tttttgatat ttgcctgtac caatctgcga tacatataat 3498241 cgtacatcgc acccatagaa gcggaaagct ctatgttacg gttaagtgta aaatttaatt 3498301 cctgaataat attttgcgct ttaatcagat tttcattttt acgttccata tcatcattct 3498361 caatggcctg agcggcaagt cttataaatt tcaaacagcc attatacagc ataagcgtca 3498421 gctccccggg tgtagccgta ttcactgaat tttgctgata ggctgtatat ggattttgga 3498481 tcgccatgtg tcatcctcca aattacattt attgtacaag aagctgtgat aaataggacg 3498541 cttgttcgtt cattttttga atcgcagaat ccattgcact gaattttgaa taatagcggt 3498601 tttctatggt attcaatctg tcctgcatat cagttatttc agtacttatc gagtttaaat 3498661 tttttccaat ggaatagcta ctagctccca ttgtcgagtt cccagcttta gcttcaatac 3498721 ttttcacagt acttctaagt gtattagtaa tccgcttcat aataccttta tcgctatagt 3498781 tactatcatt tgttccactt gtaaaaagat tagcaactcc ttgaggatct tctgctattt 3498841 ttgctttcaa tttctcttcg ttaatctcta agtgccctcg cagttggtaa gcacttgaag 3498901 ttgtgatgcc aaattcagtt aattgatagg ttttcccatc cgcattcact tgagtataaa 3498961 agtcagtccg catttggttc gtgccagtgc tgatgcttga atcgtttctc agcaatccgc 3499021 ttttcgcctt ctcctcccag agctctacct ctttatcgga catggcttct ttttgttcac 3499081 tcgtgagtgg cgtatagtct cggtattttt cttctttcag cttttcattc aggctgtcaa 3499141 ccagttcatt gtatttatct acaaactctt tgatttggtt ataaatccca tcaacatcag 3499201 tagaaacaga tgtggtaaca gggcctgtgg ctgcagttgt atttttaatc gaataagtaa 3499261 caccattcac cgtgaaattg tttgtcagct tctccatttc aaagccgttg attgtgactt 3499321 tggcatttgt gccttctttg taagcagtaa gcttattatc agcatccaaa gaaaaaccaa 3499381 gctgaccgga cataaagtca gctgtagcag agtctgctgc ctgtatgctt cctcctgcac 3499441 ctgttgcttt agaagaaaac gcaatcgttt ctacgtactc tgtaccattc caaattttat 3499501 ctttaaatgc tgatactcct agatctgagc tgttaagttt agaaatcaca ttatcaatcg 3499561 tatcggcact cgtcacacta atgttcactg tttttgctgt tgtttcgcca ggcgcaacaa 3499621 cgttaaatgc caaattgtaa tcgccttgtg tgtatcccgt ataattgttt gccttatacg 3499681 ttgctgcagt tgccaagctc gccacttcaa cagtagacga agaatttggc gcacttacgc 3499741 ttcctgtagc agttaacaca gactcattag agcttgtcac agttttgctc tgatacgtgc 3499801 tcggatatgt caacgtattt ttagacatat aatcttgcaa ttcttttatt tttgagttta 3499861 cttcacgata gctgtcacgc tgccattcaa gagtctgctt tttttgtgtc agcttatcaa 3499921 gcggcgctct ttctgtctgc atcagctttg atacgatatc atctatatcc attcctgacg 3499981 ccagacctgt tattcttgtg accatctcaa accactccta ttctactttt tttcatctac 3500041 aaataaccca agaaattcag tcatagccgc ataaaaatca agccaccgtt ttggtggaat 3500101 ttcgcggatc acttcatttg tagagtcctc tattaccttt acatagtatt catttaactt 3500161 gtcatgaagc tcgaacttca gatgaacttg cgaaggttcc aaaagcttgt tcatttcccc 3500221 caccatttca gcaagattgg tatatgaaac ttgatgaaca ggaacctcgt tatcattatc 3500281 tttctgatta tgtatttgag tatcataacg atcccaaaca ggttgtaacg tagtgagcct 3500341 ttcaatgttc aattgatcat cccctatgcc ccaatctatc gtttatatcg actaagtcga 3500401 gataagatta cacatatttt tggaaaaaaa tcttctgttt tagatttctt gtatggaaat 3500461 acatttataa aaagttagtg gagaatccgg ttattatatc atgagttagt gacaggatga 3500521 ggaatgatta ggagatagaa atttaaatta aaagaccctg gcaacgccaa ggtctttttt 3500581 aaaattaacg taataattga agtacgtttt gcggctgttg gtttgcttga gcaagcatag 3500641 cttgagaagc ctgagaaaga atgttgttct ttgtgaattc gctcatctct ttagccatgt 3500701 caacgtcacg gatacgagac tcagcagctg tcaagttttc accagaagcg cttaagttgt 3500761 taattgtgtg ctctagacga ttttgtaccg caccaagctt agcacgttga gaagaaactt 3500821 ggttgatcgc ttcatcaaca actttcaatt gagcatcgaa accgatatca gcagtatctg 3500881 ctgcattatc tgcgaatttt gttacgtcaa gatcattaac tgaatgaaga gctgcaattg 3500941 aaccatcagc ttctttaatt ccaagagcgt cagcacccat atcctcaata tttacagaga 3501001 tttgctgtgt agcatttgct ccgatttgga ataccaagtt cttttgattt gcaggagtag 3501061 ctgtgtcaac tttgtaagtg ccatcgagca atttcttacc attgaattct gtacgatttg 3501121 aaataccatc gatttcatct gttaaagctg aaatttcatc ttgaatagat tgcaaatcag 3501181 ttgctttgtc ctgagttcca gtgtttccag cttgaacaac tagctcacga acacgttgaa 3501241 ggatcgcatg agtttcagtt aatgcaccct cagctgtttg gataagagag attccgtctt 3501301 gagagttttt agaagccatt tcaagacctc tgatttgtcc tctcattttt tcagagatcg 3501361 caagacctgc tgcgtcatct cccgcacggt tgatgcgaag acctgaagaa agtttctcca 3501421 tgttcttttg gctcgcactg ttgtttgaag acaaacggtt cagtgtgtta agcgctgcaa 3501481 tattgtggtt aattctcatt gttttgttcc tccctgaata tgttgttaag gcacgtcctt 3501541 gtgcccttat tttgtaactg gctgagtctt ttgcgcctcc tcccggctac atcattaata 3501601 tcggattgtc tctgattttg ttaatacaaa aataaaaaaa tcctcacttt ttttgtgagg 3501661 ataatgcgga gatcacatcg ctggataacg ctgctgcacg gttattttct tcctgaatgg 3501721 tcaagtaaat ttctttcctg tgaatatcaa tatgctttgg ggcgtcaatt ccaagcttca 3501781 cttgatcccc ttcaaccgca atcactttta cttcaatatc agcacctatt tgaatcgctt 3501841 cgtttatttt ccgcgataaa actagcatga ttctcctcca atcggatgct ttgtcgtata 3501901 tgaggagtcg tgtaaaacga cttgcttagc catcatgttc ttgcgattca caataatggg 3501961 agccaataaa ttcgcagtag acttttcaaa tggctctgcc atagtcaata ttgtcatgac 3502021 ttctacgtct tgaatattat cgatatccaa aagttcagca gttgattcat caagatcaaa 3502081 ttcataattc ttaaaaaaga taaacggact tacgacgata aacgcaagat tttctgaagt 3502141 gacggactgc agtgccacga atggagagtc ttctgaaagc ggaagtatga cgaactgttt 3502201 ttcttctaaa aagcctggaa tcccgctttc aaaaagaatg atttgttctt cttttatgtt 3502261 catttggcca tggtacttcg tatgaatgat cattgttcac gatccttttc tttttacttt 3502321 tcgggtgatt ctttcgggta ttctacatct atatttaaat cagggtattg aagcatgtca 3502381 accttaacat ttcctggcgt atattcaaca attggcttat gcggctcagc ctgaataaca 3502441 ggctttcgcg gcgtaatctg cacatcaagc tgtgacggag tatattgtat tttcaccctc 3502501 gaaagagaag gagcataatt ttcgcctaat tgaatttggt gcatttcaga gttcctcctt 3502561 gcttgtgaag cgattgggtt ccccttattt tcaatcttca taagctcgtc gccttcttct 3502621 gcagtgcgtg ctattccctc cattacatcc tcatgccctt gttgggcggc ttcttcaatt 3502681 ctcttgaaaa catgctttct gtctaattct tcccatgctt gtgtctggtc aatcgtgagt 3502741 tttccaggtg tcaccgatat ttccatttcc gcactcggct gttcgatctc tagatcagct 3502801 tgaggctgct ccatttttaa gctggcaggc gtcgttgtta aaccaatttt tccttgaaca 3502861 ctatgcataa tcaatctggg aatctgcatc actctacctc ctgaactata aaaaaagcga 3502921 actcctaaga gccgcttact ttaaaaagtc aatcaatgta ggctgaacaa tttgcgcatt 3502981 aacggccaga gtagccctgt gcacactttg ctgcgcaata aattcagtta ttacttcttc 3503041 cagttctaca tcttcattgt ctgataacac tttggtagct gtttcttctt gcgctgacag 3503101 tcttgtatta accagttcaa gacgattata tctcgctcca agatcagatc gttcagcgct 3503161 catgccgtca gaaaaatgat caatatcatt taaaacactg tccatgccat ctagcgaacc 3503221 agaatttagt gctttctcaa aagaatcaag catttcaaat acattctgcc cgctttcaga 3503281 agtgcctcca aaagctgact ttggatctga attcactttc aatgacatat tatttgatat 3503341 attgactacg acatcagctg tatcagaaat tgtataagtt ccgtctccgt tatctgtaac 3503401 cggaggctta tctgaatttg tgccattaaa gatatatctg ccgttcactt gtgtattcgc 3503461 aatatttaaa agctgttcct ttaactgctt tacctctacg ccaatcgctt gccgctccgg 3503521 ctcgccgttt gtatcatttt gagcttcaac cgctaattct ctgacctttg acaagatgtc 3503581 aattccttct gtaatgtttg tttctgtgtt ttcgagccag gtaaaggctt gagaagcatt 3503641 gcttttgtac tgctgcactt gagacagttg cgtattatac tttaagcttt tcattgctac 3503701 tacaggatcg tcggaagctt ttgagatttt ttttcctgaa gaaatctgcg actggagttt 3503761 atccagcttc gagtagcttg aaccgatata tctcagtgag ttttgctgta tcatgccttg 3503821 tgttactctc atgtgactct acctaccttc ctccaacacc catgccgttg atcactttat 3503881 caagcaattc gtcttgtaaa gtcaccattc ttgcagctgc attgtatgcg tgttggaatt 3503941 gaatcatatt cgtcatttct tcgtctaaag aaactgcgct catttgctga cggtttatgt 3504001 cagcatcatt cagctgtgtt tctgtattag acgccagtcg attagcctct tgagcttcga 3504061 tccctagctc gccaatcaga cccgcataat aatctaaaac actagtttct ttaccgttaa 3504121 tggttatttt accggttaaa acatttgcta attttgtagc atttgcgtta tcgttggctg 3504181 cgccagtcag tgagaaagca atgtttgcgc cttttgaatc tattatgctg tcagccactt 3504241 tgatcttgcc cgccgcgccc ttggcaggtt cagtttcacc gccagtaaaa tcaaaaaagt 3504301 ctccgccttg ttcaccgctc ttggtcacac catttctgtg cacttcattg aaagctttcg 3504361 cgaattcaag cgccatattg tcaagatcag aaagcatttc cgggtatacg cccttttctt 3504421 ggccatctgc tgttatatac ccataagact ctataaaccc taaaagggat cccttgctgc 3504481 taaaggactc cgcctgtaca gctgtatccc cgattgaaat acttgatact aacccagttt 3504541 cattatcata gttggctgca agttctgaaa cctcgtaatt tttaccgtcc aaaacagttc 3504601 ctagcgactg tttattttta tcaaggattt caattgatac agttccttca gcagatgcaa 3504661 gtgcattccc gcctgatttg ttgtagctga ctttgatatc aaccattgag gataatttat 3504721 cgatcagcaa atctcgctgg tcatataagc cattcggaag aagcccgacc ggctctactt 3504781 gtgcaatttg cttatttaaa ctgtttaact gagaaagcag agaattgaca tccaacacag 3504841 ttgtatttag ctctgctttt aaattcgatt ggacatttgt aagtgattca gaaatataat 3504901 taaacgtttc agctacagct tgtccttttc gagcaacaac agaacgtgca ctttcttcat 3504961 ttgtattatt cgataattcc tgcagggaat tccaaaacga attgagcaca ctgttcaagc 3505021 cgctgtcatc cgtttcattt aaaacgcctt ccatttggga cagcgctttt gccttcgtgt 3505081 catagtatcc ggcactgttg ttttgaagac ggtattggta gtcaagaaag atatctctta 3505141 ttctctcaac tgattttcct tgaacgcccg tacccatttg tcccgctgtt ttttctgcat 3505201 ttttagatac agcagggaaa tagtcagttg cctccaatga gacccgctgt cttgtataac 3505261 catcagtatt ggcatttgcc acgttatttg cagtagtgct taacgctgcc tgctgagcgc 3505321 ttaacgcccg ccttgcagtt tcaagcccca taaaggtaga tgtcattttc tgaattcctt 3505381 tctgctaagc ttttgaatca aacagtttca ttttgctact tttcggcagc tcagctttaa 3505441 ttgatttgct gtaattgaag ttattttcct taggaaccag catatcgtac gaaatagaga 3505501 tgaattgcag cgcgtctctt gtcagctgcc tattcatctc atttactttt ttcagacgtc 3505561 cgagaacttg agaaagagat tcgtatagtt gttccagctc ttccttttca ctgcctgagg 3505621 ttttggcgat acatgcggaa atagtattat tttcgctata tccgagaaag gccgaagttg 3505681 ttttgatccg gtcatcttct gtctgcgtga ttgcttgaat atatttttgc tcttttgtca 3505741 aaatgttaga aagctctttt gttttgccgg ctttgagcgc ttccgtcttt tcttcagaca 3505801 gcgtgagcag gtgctcatgc agaacgcaaa gtcgcttcaa ttgttcaata attgccttcg 3505861 ctgacatggg ctttctcctt ttttattgct ttttataaaa attaatcata tttttcgcaa 3505921 tatgatttgc gtctactttg tatgacccgt tttcaatttg cgctttaagc tgcgcaattt 3505981 tttcctgtcg tgaaccagtg actgcgtcgg atgcatgttg catttcttta gcctgtgatg 3506041 aaatttcaat tttatcttga ggttgtgcaa cagttttttg caccgcttgc ttatcataat 3506101 ttttttgata tggattaacg gattgtgttc caaattgatt gattttcata ggattcctct 3506161 cgctttccgt tgcagtcttt aaacaatctt aaccctttta tcgactgcgt tttcagttag 3506221 tttagggaat cagctgtttt tggtattata ggcatagtat gtgtcttttt tactattttc 3506281 tttctcgatt ttcagagcat cctcgtggtt caaatgatcc atttgatcct taatatcaga 3506341 ctggcaagcc ttgcagaact tgccttctct aatcgatgtc ccgcaccttt cacaagggta 3506401 tgccaaatta ggaagatgag tgatctgaat tcgcttctgc ctgatgaatt tcaatatcag 3506461 ctcttcttcc acacctgttt cctcagttat ccggctcaaa gttgattgcc ggttttcctg 3506521 ttttcttaaa aatttataga cagtctcaaa tgatttttct tcttccttaa tacacgcctg 3506581 acatacggtt tgcagctttg tttttaaaaa taaagcattg catttcggac aattagccag 3506641 ttctcccatc tttttttctc cttattagat aatatgcctg tgtcaatttc tagtgattat 3506701 atcggcataa aaacagaatc atttagcttc tgatcaaggt aaaagatgac actgaagcgg 3506761 cttttccttt ttctaataag cagcgggctg cgaagtgcaa ggtggcgcct gttgtataaa 3506821 gatcgtctat taaaatgata ttcatacctt ctgctgaatt attttttgta tcaaaaatgc 3506881 actctgacag caggcgttct gttttctttt tctttgactg tttctcatta ttcaggcgaa 3506941 tgaggggatg gtgggaaggc cggtctaaac attctgccaa gagatgtgcc tggttaaatc 3507001 cgcgctcttc ttcccgttcc ttgctcagcg gaataggtac aagaacaaaa tgcttatcgg 3507061 ggtaaacctt agaaaaggtt gaagaaaaat cacttttaaa tgcatttatg atttctgcat 3507121 ctcctctaaa tttaaaacgg gagagcgttt ctttcatcat atcattatat gtgtaaactg 3507181 aacggttttg acgcaatagc aaactgtctc tgatccttgt tctccacacc tcgcaatccc 3507241 tgcatacggc atgaacagat tgaggtctgc cgcacagggg gcagatatgt cctgtgattt 3507301 tctttaattt gcttctgcaa gaataacaaa ccttttcatc aggctttagt aaaaaaaggg 3507361 ctctccatgt aacatcttga gaaaattgcg aatcacataa taaacagatc agtttatgaa 3507421 tgcctcctcc tgcttcgttt gacataaatc gcttggactc tctgaaacta ctgcagcaga 3507481 ttcagccaaa atgacaagca ttgctgtgtt tttttgttta tctaccagct cagctttcgt 3507541 atatgcgatc tttttaaaat cagtaacgta ggatggactc actttgttta aagaaagtgc 3507601 caatacatcg ttttggcata cttggcaagt acaggccata tgaagctggt ccatatatcg 3507661 gtcgagcagt tctttcatta cgatttcttt tgaattgaca agcattttta cagctcctca 3507721 tcatcggtta tatgagtata ctgtaccacg ttttcaaata atggctagtc tgtacattca 3507781 acttttgctg ccaattcatt catttctttt atatgctttc ttgcatcgag catactcttt 3507841 gttttgccga agtgaaagta aatgacatcg ccgtccgcat attctttatg ccggccggtt 3507901 cttcctgcaa tttgaacaag tgcgctttcc gtaaagatag acgattccgc tcctagtaca 3507961 cccgtttgca ccttggggac tgtgacgcct ctttccagta ttgttgttgt gattaataga 3508021 tcgagctgac catctctgaa ttgctgcact ttctcctttc tatgcttgtc ttccgcgtgc 3508081 acagatgcgg ttcggcaatg aacaccttta aagcacgcag cagccttttc cagaatagaa 3508141 acggaaggaa cgaataaaaa aacaggcctc ccttctttta catgaaactc tatccatctt 3508201 ttcaccgctg gcggaatttt atttcggttt aatttcttct tccagtttcc acaccataca 3508261 aagcgcggtt cgggtaaagg tttccggtgg tgtcttgcgg ggatgcgaac tgaatgtaac 3508321 tgtccgttca gtgcttttct ttttaattct ttaggaggtg ttgcacttaa ataaacgagg 3508381 gtgctgtttt tctttcttgc tttttgaaca gcgaattgaa gggtttgatc agcagaatat 3508441 ggaaaagcgt caacttcatc aatgatcata acatcgattg catctttata tcgcaaaagc 3508501 tgatgcgtag tggaaatcat aagcggagat agccgccctt tgtcatcgct tcctccgtaa 3508561 agcgctgaaa tgtcagcacc ctgaaaggca gccttgagtc ttggagcaag ctctaataca 3508621 acatcggtgc gaggtgttgc aatacataca cgcagtcctt gatttaacgc tgattctata 3508681 ccaggaaaca gcatttctgt tttgccagcg ccgcaaaccg cccagatgag gagctcttct 3508741 ttttttgata ttgcttcaat taaaacattg gcggcttttt gctgtccgct tgaaagcttg 3508801 ccatcccatg tcagcttaat agacttccag tttgattcat tttcctcttt ccatgaatat 3508861 aaaggaacct cctcactcac tctgcccatc atgacacagg aacggcaata cagcttattc 3508921 tttccagatg agtgataaaa agaaaaatac cgctgatcag tttgtccgca cctattacat 3508981 ctatatctcc gtttatttat ggatatagaa ttttcagcag tgatatatcc attcttgata 3509041 tgccattcaa tcatctcatc ggaaaatgag agctcagtcc tgagcaaatg acggcttcga 3509101 agcgtctgct gcaattcttt tgaaaaggaa ctgttttttt caactggcac attcacatag 3509161 cacgcctcct ttcgaaacag tatgcctgaa tgaatatttt ctgtccaact attaaaataa 3509221 gaatataaaa aaatctccgc tctaaaaacg gagatttggc cttatttaaa acaccagcaa 3509281 attcctaacg caccttcacc caaatgagtg ccgattaccg cgccaaaata gctgttataa 3509341 aattcaacat gaggatattt tgcagaaagc tcttcaatga ttttcgctgc ttcttcctct 3509401 cgattagcgt ggataacagc agctcgcata ggcaaccctt tactcgcatc ttcgtctaaa 3509461 agctcataaa ttcgcgaaat tgctttttta cgtgtgcgaa tcttctcaaa aggcacaatt 3509521 accttattgt caaaatgaag gataggcttt acctttagaa gactaccaat gaaggcttgg 3509581 gcgctgctta atcgcccgcc gcgctgaaga tgggctaagt catctaccat aaaataagct 3509641 cgaactgttt ttttcatttc ttccagttct tttataatat cttccggcga tgatgctccg 3509701 tttttgatta attcagcagc tttaagggca taaaagcctt gagccaagca gctgatctct 3509761 gagtcaaatg gatacacatc aatattgtcg accatcgaat cagccgctgc tgcactgctg 3509821 aatgttccgc tgatcccgct ggaaagatgg atactgataa ccgcatcata agacttgcca 3509881 agctcttcat acaacgcaac cagctcgccg attggcggct gagaagtcgt cgggagctca 3509941 ttatgttttt tcacttcttc ataaaagctt ttccagtcca actcaatttc ttcacggtaa 3510001 gtctcctccc taaaaacaac ctggagaggg atcatatgta tctgatgttg ttcacgcatt 3510061 tctttcggaa tatatgccgt gctgtctgtt acgactgcaa tattcatagc ttcgatacct 3510121 gccttattgc tttataactc tattgtaagg gaaacggcag cctaaaaaaa gacctgccta 3510181 gtaaaaggca agtctcctat tatactatct catttctacc cagccatttt taatggcgac 3510241 cacaacggct tgcgtccggt cgtttacatt cattttttgt aaaatattgc tgacatggtt 3510301 tttaacggtt ttctcactga taaacaatga ttcaccaata ccgcggttgc tttttccgtc 3510361 tgcaagcatc tgcagcactt cacattcccg cctagttaaa atatgtaatg gtctgcggat 3510421 ttcagggtaa acctcatgtt gagggtgtgc agaaactccg cttgttgcaa ggcggcggaa 3510481 ttcgttaacg aggttgtgag taaccttcgg atggaggtaa gatccgccct cagccactac 3510541 tttaaccgct tcaattaatg tatcagcatc catctctttc agcagataac ctcttgcacc 3510601 tgttttcagg gcatgtgtta cataattttc gtcatcgtga attgatagaa taattacttt 3510661 agattcagga tacagctcta caagctgttt tgtagcttcc acaccattta cgtttggcat 3510721 attgatatcc atgatcacaa catcaggatg atagtgctca acaatacgag ccgcttcgtc 3510781 cccgtcatca ccttcggcta ccacttcaaa ggtaggttca aaatccaata tccgtttaac 3510841 accttcacga aataactgat ggtcgtcgat aataacaatg tttactttag tcacaagcca 3510901 cgcctccttg tattattgtt ctatatactc tagcattcgg tcaatatgcc ttttggctct 3510961 attttacaaa tcatagtcaa agagataacg gaaccttaat cataataaat gtcccaagac 3511021 ctattttcga atctattgtc atcgttcctt ccaataaatc tactctttct ttcatgccca 3511081 gcaagccgaa tgatttgttt ttcttctctt tcgcttcctt caggtcgaac cctttaccgt 3511141 tatcttttat cattaaaatc acaaaatcct ttgtgatctc aactttgact gtaatttctt 3511201 cagattcaga atgctttagc gcattagaca cagcttcctg tgcgagcctg aagagcgcaa 3511261 cctcaaactg aggcgctagc ctctgatcct ctgtttctcc aatgcactga aaatgtattt 3511321 tgaccttccc gttatattcc tcggttgtat atagatattt tcttaaagtt ggaatcaggc 3511381 ctaggtcatc aagggccatc ggtcttaaat catatataat ccttctcact tcgtaaaggg 3511441 cattccgaac attttggcgg agatttttaa tttcttggaa tccgtcctct gcgccccggt 3511501 cacggaaaat ccgctcgatt aattccgatc tcatcataac attcgccagc atttgagcgg 3511561 gtccgtcatg gatttctctt gagactcttt ttcgctcttc ttcctgcgcc tcaataattc 3511621 ttaagccgaa atcctgtttt gcctgagcat cagcaagaag cagtccaact tcgcgcaaat 3511681 cctgattcaa gtagttgagc acaactgtaa tttggcttac taatgattct gaccgctcaa 3511741 tgatttcctg aagccctagc aatctgcgct ccaaatcgtc ccgccgttcg cgcaattgct 3511801 tctcacgctg ctggatcatc gtcaattcta cctgcagctt atgggctttt tcataagcat 3511861 tgcggatttc ctcttcactg aatctatgaa aattacggct gacctcggat aaacggtttc 3511921 tcgcatggcg agtttgcact tcaagtttat cgccaagctc aatcacttca tacacctgct 3511981 gtttaatttg tttcagttct tcgaccagct gttcatactg ctggcgtgac tgctccccga 3512041 tttgaaaaac ctcgtccttg ctcccgtcaa cggttttcag catcttcatc aaaatagaat 3512101 ccagcacttt ggaatccatc tttgttttat tcataatttc cctccgtcac ggcgttgtca 3512161 tatattttta ttataaatgt aattgatctg caaattatgt cgaattataa tgaaagaatg 3512221 cgtatattct agaaaaaaac atttttatat actatctact ctttatgata ccaaaatacg 3512281 cacaaaaatt ctaaagactg tacgaatttg tataggcagt cttttatgct tagcaggagg 3512341 gtcagctagc atgctgcaca gctattttac tgtgaaagaa gcgggagaac acgagattgt 3512401 tatagaaaaa tcgcgtttta tctgtcattt aagccgtgtt tctaccgaac aagaggcaca 3512461 ggaatttata cagaaaataa agaaacagca ctggaatgcg actcataatt gctcggctta 3512521 tgttattggc gagaatgatc atatccaaaa agccaatgat gacggggaac caagcggtac 3512581 agcgggagtg ccgatgctcg aggttttaaa aaaacgcagg ctgaaggata cttgcgccgt 3512641 cgttacacgc tacttcggag gcattaagct tggtgctggc ggattaattc gcgcttatgg 3512701 gaaatcagtg tctgaaggat taaatcatat aggtgttgta gaacggaagc ttatgcgaat 3512761 catgcatact tctgcagatt acacatggct tggcaagatt gaaaatgaat taagggagtc 3512821 acaatttctg ttaaaggaaa tccattattc agaaaatgtt gaattcgaaa catacgtgga 3512881 agaaaaagaa accaacgctt tttctgaatg gatgacagaa ctgacaaatg gaaagagtga 3512941 tattaaagag ggagagttga cgtatcttga aaaagccgtc aatcacataa aggagactga 3513001 ataatggctg aacgcgttag agtgcgtgtg cgaaaaaaga aaaagagcaa acgtaggaaa 3513061 attttaaaaa gaataatgtt attgttcgcc cttgcactat tggtagttgt agggcttggc 3513121 gggtataaac tttataaaac cattaacgct gcggatgaat cgtacgatgc cctatcccgc 3513181 gggaataaat caaatcttcg caacgaagtt gtagacatga agaaaaaacc attttctatt 3513241 ttatttatgg gaatagagga ttacgcgact aaaggacaaa aagggagatc agactctctt 3513301 attgttgtta ccctggatcc caaaaataaa accatgaaaa tgctgagcat tccgcgtgac 3513361 acacgtgtgc aattagctgg tgacacaacg ggaagcaaga cgaagatcaa tgccgcttac 3513421 agcaaaggcg gtaaagatga aacagttgaa actgttgaaa acttcttgca aatcccgatc 3513481 gataaatatg tcacagttga ttttgacgga tttaaagatg tgattaatga agtcggcggt 3513541 attgatgttg acgtgccttt cgatttcgat gaaaaaagtg atgtagacga aagcaaacgg 3513601 atttacttca aaaaaggcga gatgcatttg aacggcgaag aagccttagc atatgcccgg 3513661 atgagaaaac aggataaacg cggagacttt ggccgtaatg acagacaaaa acaaatctta 3513721 aacgcgctga ttgaccgcat gtcaagtgca agcaacattg ctaaaattga taaaatcgca 3513781 gaaaaagcca gcgaaaacgt tgaaaccaat attcgcatta ctgaaggttt agcgcttcag 3513841 cagatttaca gcggctttac cagcaaaaaa atcgacacat tgagcattac aggttctgat 3513901 ttgtatttag ggcctaacaa cacatattac tttgaacctg atgctacaaa tctcgagaaa 3513961 gtcagaaaaa cgcttcaaga gcatttagat tatactcctg atacaagcac tggcacttcc 3514021 ggtaccgaag acgggactga cagctcaagc agttctggca gcactggcag cactggcaca 3514081 acaactgacg ggacgacgaa cggaagcagc tattcgaatg acagcagcac aagctcaaac 3514141 aacagtacaa cgaattcaac aactgattca tcctattaaa aaatgcccgg tccttttaga 3514201 ggatcgggca tttttgcgca gaaaaaaact ccggcacata agccggagtt tttaattcct 3514261 tttcaccagc cgtttataaa actttgtaaa cggcttaaat ttttcattca cgagtcctgt 3514321 cacttctgct atgatttgca taaaaataat caaaatgaag ataataaaca aagaaagcca 3514381 aattgtggca cttttaagta caatcgcact gatactgaaa ataaatccaa ttaaataaat 3514441 aactaagacc gacatccgat gtgaaaggcc aaaggccatc agtctatggt gaatatgcga 3514501 cttatcaggc gctgaaatcg gctgtttgtt taatattctt ctgatgatag caaatgttgt 3514561 atcaaaaatc ggtacgccta atataataat cgggataacg atactgaaca atgtgacact 3514621 tttatacagg cctaataatg aaagaatcga gatactatac cctaaaaaca gtgatcccgt 3514681 atctcccata aagatttttg ccggatggaa gttgtaaaac aaaaacccca gcgtgctggc 3514741 aataacgact aatgagagtg acagaatgag cacttttccg ccggatagcg ccatgacagc 3514801 aatcgttgac aggccgataa cagaaagacc ggcagcaagg ccatccaatc catcaatcag 3514861 gttaattgcg ttcgtgatgc cgacaatcca taataccgtc agcggataag ccatccatcc 3514921 taactcaaat cgttctgtta aaaaaggtac tgagaaaaag tccattttta agccagtgct 3514981 tacaatcata atggctacac ctaattgaat caaaaactta acttttgcac ttaattgata 3515041 tttatcgtca agaataccta acacaataat gatgaatgct ccgactgtaa ttgccgtcat 3515101 ccttgtttct gtgtaaatac cggatgcaag cacgcctgca accaccccga taaatatggc 3515161 cagcccgccc atgcggggca tgattttgtc atgtactttt cgattgctgg gctggtcaac 3515221 tgcacctatt ttaatcgcaa tcctttttac gattggggtt atgattaaaa ctgtcagcag 3515281 cgagacaata aacgcaacaa caatgcgaat catgcgttcg tcaagcataa agaagtctcc 3515341 tttggaatta aatgaagtct ttatttatat agagaaccgt tccttccatt ataccttctc 3515401 cttagttatt ataacaagct tcatcaaaaa gaaacacgta taatcaaaaa acgcgcatcc 3515461 caatttatag gactacgcat gtttttgaat ccctgtatat ttcataattt gtctaaataa 3515521 gcaattccaa tcttgtgtcc gggcgatgtt tcggcgcatt tctttatagg tctcgtctcc 3515581 gttttgaccg agaacttttt cacaagcggc tataaaatca atcggatgat cgccctctac 3515641 atattcgtat acatacggct tttgcatttt tgaggttgac ggaagattag tgcctacaac 3515701 aggttttcct gccgctaaaa attcaaatag tttcagcgga aacacagctt gattatacgg 3515761 tgattgttta tatggcataa tgccaatgtc gataagctcc atataatgag gcacttcttt 3515821 tggatctgcc ggaccggtcc atatgacatt gggaagcctc agcagctctt gaaacgaaac 3515881 atcaccattg gtggcatccg ggccaaccca taaaaatgtc caatcaggct tttgcagtgc 3515941 cgcttcttta atcattttaa aatcgagctt cggtttaatc ccgccaataa aacctaacac 3516001 tattccttct ctcccctgca gtatactgcg atcgggagct tgtttatttg cagaaaacag 3516061 ctcatactcc acaccgtttt ccacagtatg aaccttttct cgtcctgcag tcagtttttt 3516121 gtctacttcc ttgtgaagat aatctgatga acaggttatt gaatctgctc gttgtataat 3516181 tctcagctct gccgatttaa tgacttttcg ccggaattca gacagcagat ttgatcggcc 3516241 gctgatcggc gcagcccata ggtcactgca gtcataaatg acctgatccc aagaatacag 3516301 cgaagacagc agcgggaatc cgggaaacgt gtaccataaa cagcagcgtt caccgtttgc 3516361 agaagcaggt gtaagctcat cgagtaatgg ggagagctta tgtctgtaaa agacatctgt 3516421 atatcgtccg aaacgaaaca tttttttctg cagcaggtct ttgacagcga attgcctgat 3516481 gccagaatgg acttcctgaa actctttccc ttgggcacgc ggagccggac atacccaaat 3516541 aacttccttc gtttcctcct gagcagctaa aaattctgcc agccggtgcc ttctgtatct 3516601 caattggtct tttccccatt cagcagtggc aacgatgaca tgaatgattg cttcttttgt 3516661 ttccaccttc atcacctttt ctctctgttt gcagctataa tctttttttc accgcgtttt 3516721 ttgcatattg aacaaaacac catgttgctt tcataaaatg aagccgttcg atctccctgt 3516781 agacaaacca cgtttttttc gcagccttcc atttgttgct ggaaattgaa ttattgacaa 3516841 gccgatattc agccaggcat tcattcattc cataggcagt aaatcctttt tttaaaagag 3516901 acagccatgt ggctaagtcc tgtctcgttc tgatattcgg catttggatc tgtcccgttt 3516961 gctccctgtc aatcatcacc gtcaagcagc cgataattgt atttttcagg gcgtcatcgt 3517021 acgtcaggct ttccggcgca tgaataaatt tatcgagcgg ggtcccgtcc tgcgccatta 3517081 agctgtagcc cgtgaaagag aacgcacagg agcgctccat cataaactca agctgctttt 3517141 ccagtttgtc ttttttccat ttgtcatcac tgtccaaaaa tgctacgtag cgcccttgag 3517201 cgcgttccaa cgctttgttg cgagcaaccg cagctccgga gttctcttcc agatacacca 3517261 catgaattct ttcgtctatt ttttcatact gctgtaaaat gtcgcgggtc ccatccgttg 3517321 agcaatcatc cacgataatc atttcccaat gaggatggct ctgatctaat accgaatgaa 3517381 ccgtgtcttc aatatagtca cgcgcattat aggaaggtgt aatgacagat acgagaggtt 3517441 tccaattggt catgatcaca tctccatcgt atgattttaa aaggattctc tgaaaaattc 3517501 aggaatgaca acgaacataa aggcaatcgt aaggccaatc ataacgccga gaactgcttt 3517561 ctttttcgga gacataccgc cgcctgctgt ctcacttacg gtttcggaat cagtaacact 3517621 tgccgctttc aggttaagct gtgtgttttt gagttcatat aaaaatctct ctttatccac 3517681 tttggaatcc tcgctcaccg actcgccttc aagcgcgtct atgctgctgc ggatgacggc 3517741 ttctctttct gcatacagct tttgatcgtt tttgaggaag gtggaggata tggcgtttaa 3517801 gacagattcc gttctatcct tatcctcgtc actatagctt aaagtcagta acgatttgga 3517861 ttccgtattg attgtaagct tctctttgat ctctgctaca tcttcatcct tttcatcagg 3517921 aagcgcctcc ttcaaaaagg agtcgctctt taatagaagc ggaatctctt ctgtgctgtt 3517981 ataaaccgga tgatcatagc tccccacagc caaagtatct tcagctgtat agctcttttg 3518041 atcagcgatc tgtgacggca ggatataccc cgccgcacct aatataattg gcaccgctat 3518101 gatccaaatg atattttttt ttatgcgacg ggctattctt atcaatatat cgttcatata 3518161 agtctccctg ctttttgtag tctgtttatc tgtacatcgg ctcaggcatt tgtctggatc 3518221 gccttaacac attcacggcg gcgatgacga gcgccataaa cacccaatgg aaaaataaat 3518281 ttgaaacaga gcttgggctg atacttgata ccaggaaact gaccatagcg gtaataagtc 3518341 cttctgtgat cagttttgac tgattttcta attttctttc ataaaacttg taaagcaccc 3518401 atatgaggta ggcataaacg gacaaatatc ccagcatgat gaacaaacca aaattagcaa 3518461 gaatttcaac aagccagtta tgcacctctg ccacattgtc agtatcatat acagcataat 3518521 gctcaagata ataggataca tttcctgccc cgactccgaa tccgtatgaa tcaaggaaaa 3518581 aatgccaagc gtttttcagc agatttgccc gagccacatt tgatggaagc ctgtcatgaa 3518641 atgaatgcag cgtctgcggg gccagaaaca gctcccaaaa ctttgaatag attttgctgg 3518701 cgaaaagaac tgcgaaaaga gcaattcccg ccgccgacag ccatatagcc attctcttta 3518761 aaacaggcgg caatacaatg aagatgtaga cagcaatacc tgcaaaaatg cccagaaggc 3518821 tggctcttga accagtggca aaaattaaat acaacgcaca gagcgagagc acaaggccaa 3518881 ttgccttgat gtatccattc ttaatgtttt tcatcatcgt gatgtaaaaa aagaagctga 3518941 tggataaaaa ggtcgcaaag tcattttgat taaaaaagac cgatgtcgga taatgctgct 3519001 tgtactccgg tccgctgtac aatgtggaac tcgcaagatg atggtgggtg atatgattgt 3519061 aaaaaccaat gatcatcaga aataccgtca tcaccagcca aatggcataa acaatcatca 3519121 gccgctccat tttttgcacg tacatgacaa taagataaat gaagaagatc cccattgcca 3519181 ataaggctaa atacttgagg ccaactgtta ccgacttggc ccacagcaga gaaacaaggc 3519241 catatataaa ccaaaaggcg aaaaagagta aaatcccttt tacttgcagc ccatgccatc 3519301 tttcaatatg ggttcgattc cgaaccatgc cgaaaatatg aaggcaaccc gctgcaatga 3519361 gcagaagccg gtaaaggaac aaactgaaaa atccaagatg aatggcaaaa aatgcattat 3519421 ttaaaaaagt gcaggcgatc aaaatataga ttacagccat aaagagccgt tcttttgttg 3519481 taaatgcggt tgcaagcgtc agtaaaaaca ggccaattgc caacaccgca agcacagcag 3519541 ccatctgcat gaaacctata tctttatgga tggctcccag caataggacg actccaaata 3519601 tagcagcggc cagtaacgct agcgtatgga ccgctgatcg tttgatactc acatgtttaa 3519661 cccctttcct gatgtttcag gagccggcgg ccgagcctag cagccggcag cttcaaccaa 3519721 gtaacacttt ttctttttat aaattgacgc ttcccaagtc tttagccaat tcttcaagcg 3519781 gcaagcccgg aaaatacttg tcagagggtt ccgttccccg aacagcggga cggccgatag 3519841 agtgataaat gtatccggct gcctgcatct cttcaagtga aaataaattt ctgccgtcaa 3519901 tgatgactgg ctgttttaag agggttttca cttttacaag ctccatttct ttcacttccg 3519961 gccaatccgt taaaatcagg catgcatcag tgtcttccat cgcagcatac acatctgtgt 3520021 aatactcgac ctgttcgcca aggatcgctg aagcttcagg aatagcaatc ggatcgtatg 3520081 cttttacatg ggcgcccagc tgctgcagca ttgggataat atcaagcgct ggagcggatc 3520141 tcacatcgtt cgtattcggt ttgaaggcta atcccaggac tgaaatggtt ctccctttga 3520201 cgcttcccat aacagtcaaa agtttatcta caatatgaac acgctgcttt tcgttcgttt 3520261 caatgacagc ttcgatgagc ttgaatggat agcctgccga ttttgcgatt tgaagcagcg 3520321 cggttgtatc ctttggaaaa catgaaccgc cgaatccaat accagcttta aggaactttc 3520381 tgccgatacg gctgtcaaga ccaacaccat cagcaacttt tgaaacgtct gcgccgactc 3520441 gctcacaaat gtttgcgata tcgttgataa aggaaatctt tgtcgccaga aatgcattcg 3520501 cggcgtattt aatcatttct gcactttcta ggtttgtttt aatgacagga gcatggaatg 3520561 gctgatgaag ttcctcaatg atggcagcgg ctttatgact tgttgaacca atcacggcac 3520621 gctccatatt catcgtgtca tgaatcgctg acccttcccg aaggaattca gggttagata 3520681 caacatcaaa tgagtatctc ccctttgagg ctttttgaac gatagattgc accagtttcc 3520741 ctgttccaac cgggactgtg cttttattta cgatcacttt gtagccgtta agatgctcac 3520801 cgattgtttt cgccgccgct ttgacgtacg ttaaatcagc ttcacctgtt ttggacatag 3520861 gcgttccgac tgcaatataa ataatatctg aggcccgaat ggcagacggg atatcgttcg 3520921 taaaggtcag gcgctgatcc agcacatttt tttcaactaa gtctgcaagc cctggttcat 3520981 agattgggat taccccattt ttcaggcttc tgatttttga ttcatcgata tcacagcaaa 3521041 caactttatt gccgatctcc gcaaagcaag tgcctgatac gagtcctaca taacctgttc 3521101 caatgacagc tatttttttc acagcgctca accctctcct gtaaaatgat cttccaattt 3521161 ataatggtcg cagtgtctta cgattaaacg gacgttttcg tgaccgtctg atactgatga 3521221 tgcaaggcct tggcgttttt tcctgcgtca aattgagcct gcacggtttc atacaagtca 3521281 tctgctactt ccggcttcca tatttgctca tgttcgtacc gagtgatcgc ttccgccaag 3521341 gcttgagcgg atttcggttt aatcagcaga tgttggtgct ttccgaataa agacgacact 3521401 ccgccaacat ccgtacaaat aacaggaacc cttagcgcca gcgcctcaat cacaacagtc 3521461 ggcatcccct cactgtaaga aggaagtacg aatagatctg ccgcaagtaa atagtctctt 3521521 acctgatgat tcgggacttg gcctgtgacg atatgcccct tctgcgtcag cgtcgatttt 3521581 gcgggaccat ccccgacaaa gactgcctta ggagagtcct gcagcgattc gatcgcttca 3521641 gacagttcaa aaatgccttt ctctctgacc agccggccga catagacagc cagacgctga 3521701 tcgagcggga gtccgagtct ttttctgatt tcctctttcg tctcctcatt cccctgaaaa 3521761 cggctgagct gtatgccgat tggcaaaacc gagctgtcaa agcccgaaag ctttttggct 3521821 tcttcctgaa gcttgtggct gactgctaaa acaactgacg cagaacctac ggcacgcttg 3521881 aaggctttaa acgcaccttt gctgtaatgc ggatagacat tcacatcact gccatgcaag 3521941 gtcaggacat aaggaatttg cgctgactct gacacgactg ccgcagcccc gcccgatggc 3522001 atggcaaaat gcgcatggat cagatccgga tataggtcgc gctgtttcat tgtttttaaa 3522061 acggctgatg cgattctccg atgaggctgc gcccacttca gctggccggg aactgcccga 3522121 tagaaaggcc ggtaaaccgg tatccccttt ctaatctcat actccggtct gacatccttt 3522181 tttcgatatg tctttttcag catgcggaca ggtgctgaat gaaaaggccg tgggcatatc 3522241 acagtgatat caagcccgag tttttgcagc tcttgcacct gtgtctcatg aaacacaccc 3522301 tctccgggtt tcatactgct cggatatacg cttgtgatcc acaaaatctt catgacaaac 3522361 gtccttttct tagtagtttg cttttcgttt gagggtacgc ttttaccaaa agaaagagat 3522421 agcacagcgc cccagccgca actgaaatgg ccagccgcat ttctgcctgc atactgaagt 3522481 gttcggtact gaggcttaca ccaaacgcga tgatgcccat cgccgcagta atcagaaatg 3522541 gcttcataat cgactggaaa taagctgaaa ggttaagctt gatgacatat gccaaaagcc 3522601 agcgcccaat caggaaatta acaacgctga taatggcata cacccatgcg actgtcagca 3522661 ggcttcccgt ctgtacagct gcaaacagtg ataatccgta cagcagcagc acgccggaat 3522721 cccaataaaa cgctaagtca gctcttcctt tagccagcaa cacagatcca tttggattca 3522781 tgagcactct tagtattccg acaatcgcaa gaacatttag gatcggaaca gcagcaagcc 3522841 atttttctcc gaaaaccgct gtgataaagg cgtctgacac agacacgagc ccgattaaca 3522901 gcggaaacga aacaagcgcc agcatttttg tcatattcag aaagccttct ctgatcacgc 3522961 tgttttcata tttgtttttt gcgaaaatag ggaatgccac ccgtgtgaca atcggattga 3523021 tcttcaaaac cggaatggtg acaatctgat aagcgaggtt ataaatcccc aatgcttcag 3523081 caccaataaa ccggccgatc aaaatcatgt cgatatttgc tcccagcctg ttcacaagac 3523141 gggatgaaag ctgaaaggct ccaaaagaaa agaaatcctt catgcctctc aaatcaaaaa 3523201 caaaagcagg atgccacttt tttcggtata cagcccaata taaaatccct ttactggact 3523261 gcagcaggac ttgagaaatc acgtacgcca aaatcgcatc catcataaaa accgctatcg 3523321 ctaaatatcc gaatgacaat acatttgaaa aaatctctat tttgcttaac gtattaaaat 3523381 gcagctgctt ttgcagcata tactgatatt gctgtccaat tggcgcgatc aaaaacataa 3523441 tcgccagaat ccgaaccaga aacaccagct cttctctttg ataaaatccc gcaatgacag 3523501 gactgctcac atataaaaga acaaacagca aaacgcccgt cataatgtta agccaataca 3523561 atgttgacag ctggcgctcc gtcgcgtcgt ctctctgaat taatgctgcg ccaaaaccca 3523621 tatcgagcac aatctgggcg aaaactgtaa ccgttgtgat catgccgaca agcccaaatt 3523681 ctgttaaggt catcatattt ccaagcaggg caaactgaac aatttgtatg attgtaatac 3523741 acatggttga aatacttgtc cactttgcac cgctcatgat ttgttttgta atacttggca 3523801 tcatattccc tacttctttt taagctcaga ttgatggtga ataatggaat cccgttttat 3523861 cttgcaccat cacccgtcca aactacttta caagttttta acataatttt taattctaaa 3523921 gtgaaagtca gattgcgaat gtaatataaa tcaaatatca gcttttcctt cggcgtcata 3523981 tcgtaaccgc cgttcacctg agcccagacg ctgtgtaaag cctggaatct cattctggaa 3524041 tttttccgta aatacgggcc gttccggacg agggccaatc atactcatat cgcctttcag 3524101 cacattaaac agctgaggaa gctcgtcaat tctcgttctt ctgataaaag ctccgatcct 3524161 tgtcacccgc ggatcttgct tctgtgccca aaccgcccca gacttctcgg catctatttt 3524221 catggaacga agcttataaa gcttaaatgg cttcccgcct ttccctacgc gttcctgcgt 3524281 ataaatggca ggccccggcg tctccaaaca aatcaaaatt gaaaataccg caatcattgg 3524341 cagcgcaatc gccaatccaa tgagcgcaaa ccaaatatcc attacgcgct ttattgccaa 3524401 ataacgagcc gtcttttcag ataatgtaaa agaatgtatt tgttgaactg agaattcacg 3524461 actcacattc atgcttttct ctgcactcac tgacacacac ctcacgattt gtttgggatg 3524521 ttatgatgac ctatgccagt cagtttagca gacggatgtt aattggatgt aaatggtatg 3524581 ttaagaagtg tgaattacgt gttttttctg ataaatgttg ttaatactct tttactattt 3524641 tatatacaag tcctatttgt tttaatcatt tcatataaaa aagagacaaa tctgtgatta 3524701 gatttgtctc tttcgattat ctgtaataag atactgtgcc gtcatgaata gcttgtgcag 3524761 ctttatcttt ataaaccgct tgcttcaatt tacttgcatc tgatgcatta gtgataaagg 3524821 cagtttcaac taaaacactc ggcattttag aatatttaat aacatagaaa gcagctgttt 3524881 ttactccccg gtctctcgtt ccaagattag ccgctaactt tggttgaatt tgttcagcca 3524941 gtctcttgct atttgcagct tgatatgttg tatcgtagta cgtctcactt ccatttggtg 3525001 atgagctatc attagcattt gcatgtatac tgagaaataa atctgcttgt gcagaagctg 3525061 ctttatttac tctctcctgt aaagaataaa aagtatcatt agatcttgac agtactggaa 3525121 gagcacctga agcatttagc tttgtattga ctcttttcgc tatatcaagg ttgacttctt 3525181 tctcaaggag tccattgccg attgctcctg aatcttgatc accgtgaccc ggatcaataa 3525241 agattgtttc acctacaact ggattcttta gctgattagc aacctttgtg cttacggcag 3525301 gagtgtttcc gataatcata aagtttgaca tgtttttact tccaataatt ttacgggctc 3525361 ctgtagataa attttcacca tttgtaagaa taagagattg cttcttctta gctgccagtg 3525421 tagctcctgc aatagagtca gggtagctga atccattgct tacatatacg gtgcttgttg 3525481 ataaattaag tttttgtacg atatttgcag caagctcata tctgtttgaa ccgctaattc 3525541 ttgtaggaga aggtaacttg ttgtataccg tattgctgat acttccagtg cctcctacaa 3525601 caacggtact cgaaattccc ttatctttta tcacagacgt agtcgcacta tttatagatg 3525661 ttttatttgt aaaaagaatt ggatacccgt ttttcgctgc ataagggatg acggccggag 3525721 cgtctgcata taagaagccg ttcaaaataa cagcttttga agtcgcaccc atcgcttttg 3525781 ccacccgtgc agccgtatca taacggttgc ttcctgcaat tcgtttaata cttatcccca 3525841 agcttttaat ctggttagca gtgttagaag aaacagcagg tgttccgcct acaataatta 3525901 catttttagt ctgcatctct ttcaatcttg ttttcgtttc atatgaaagc ttatcagaat 3525961 tagtgtaaag caatggcgca ttcttctggt aagcaagagg tgctgctgaa atagcatctg 3526021 cataggaact cccaccaaca attacagctg tacttgctgt tgaatacatt tgctttgata 3526081 tttgtacagc agtgccgtat ctattgcttc ccccaactct tttcactgag ttatcggcca 3526141 aagctgttgg cacaaaaagt atgagcccca gaaaacacat tgttaggact tttatataag 3526201 aacgcaattg atttcctcct taaatggcgt tatatcctaa aataatcaat aacttgtcag 3526261 agttgtacct ggatagtaaa atttcaaaat tgaactatat gaatctccag cttctgctct 3526321 tgcttttgct ccatattgac tcattccgat cccgtgacca tatcctttac cgctgattgt 3526381 gtactttgaa gtatcttttt ttacagtcac ataagtactt ttaaatacag tcgctccaat 3526441 cattgttctt aactcacttg ttggtacact aatggttgta attttgctca agttatagga 3526501 gccagtactg cttttaacaa aatacttcac tttcatcgat gctgtttttg cacgctgccc 3526561 ttgtgtcgtt ccactaaagc ttaaatcgtc aatacttgca attttgacag aatcagcgct 3526621 tgtttcttta tttttcaaga tccagttctt aactccggaa agtcttgcag aatcagtttc 3526681 agtcgctgaa gaccaccaag aagaaggctt cgttaagtcc aaagatttcg tatctagctg 3526741 ttgttttgac aaagtaagcg tccagcctat ttgaggatcc tttgtatctt tttttgcaat 3526801 caagtaaggt acacttgacg accacacttc attactagct tctgtgtaac caccattact 3526861 ggaagaataa gctgcagtta taagagatcc attatatttc agaactttcc ccttcgtttg 3526921 ctctaccgct ttattggtat tcgaattcca actgtagcca ccataaactt gaaaagcggt 3526981 tgtatcaggt acagtagttc ctgtttttgt tattgagtag gttcttgcag cgacagtctg 3527041 tgctttaaga gcctcaagtg accagctagc aggcatttca ttcggaatta ctccttttaa 3527101 gtaatcctca aatggaatat tctcatttac cggtcggata tatttagtag actcaataga 3527161 gaaattaacc gtgccaagat actgctttcc atcaagacta attctgtttg aagtagaata 3527221 gttttctggt ttaattctta gggagtttcc gtaagttttg atgttttcaa ggtttaattt 3527281 tccgctgttg atttttagat tataggtgcc accgtcagct aaataaaatt catcagcaag 3527341 tgaattctca acttcagcag aaattgaact ggtacttcca ataaagtcgt atgcatatgt 3527401 ggctttatct ttcgttatac ttttagccgc agccggaacg ctatcttgtt taacaaataa 3527461 aatttggctg tttttcttcg aggcaagcga agcgcctatc aatacgtctg catattttgt 3527521 cccgttcgtc attacgactt tatcagcctt caactttagt tgcttaatta tatttgccgt 3527581 aagttcatat ctggttgatc caggaatcct ttgcacagtt gaagtttttt taatttggtt 3527641 ttctacacta tcactgacgc taaatgaact gcctataatg atgacttgtt ttggcaaatc 3527701 ataatccgga agcttgtctt tctctgtaag caaaataggg tatccgtgtg ctgctgcata 3527761 tggagcaatg gctaaagcgt cttgaaatac tcttccggtt acaacgatcg ctttatcata 3527821 gctgcccatt tgctttgcaa tattttctga taagacatat ctattttttc cgcttatcct 3527881 tttcacagcg ccatatgatt tcagcttgtt ttctacgtct tttgaaatgc ttcgcgctcc 3527941 cccaatgatt aaaatattat cagggttaaa cttagcaatt tgtctttcag tagtttttgt 3528001 taacgtgtca ggctgagtaa ataaaactgg tgcgttcagt tttttcgcca atggaataac 3528061 aggcaatgca tcaataaaaa tatctcggtt caccaatatc actgtattag gatttttcca 3528121 ctggctgttg gatgcaagag tcgcagtttc gtatcgtgaa gcgcctgcaa aacgatccgt 3528181 aacagcaaca ttatctccag ttactttata aaatcctgtt ggcgatagac tgatgctaga 3528241 tttatttcca atataattta acaatttaac tgagatgttt gagtctgctg caaaagaaac 3528301 tgatggaatc aataataaga ttgcagcaag tgaacacact atcaattgtt tgcaagattt 3528361 caaaatttca ggttcctccc tatatcttag ttggcacgtt caatatcttt taacagaagc 3528421 tgaccctcat catttttttc atatgtaatc gtgaccttat ctccactgtt aaacttatca 3528481 agatcacttg tcgattcttc agtgatatca agactaaccg gctcattatc tactgttact 3528541 tctattgtat gagtatcagc taaccctaca taagtacctt cttttgtttc aatgttactg 3528601 tctggcgata catcttcacc ttgactcttt tgactattaa ccccgcaacc cgaaagaagc 3528661 aatataaaga acagtaaagc aataaatttt ttcatttttt tcacctcatt atattttatc 3528721 gtcaacctat tttatatttt aaagaaaaat taagaaacaa tgaaactttt ttttataaaa 3528781 aacgactatt ttaggatttc attcttgtat taaatagagt tgtatttatt ggaaatttaa 3528841 ctcataatga aagtaattta acagacgagg tgcaaaggat gagaaacgaa cgcagaaaaa 3528901 agaaaaaaac tttattactg acaattttaa cgataatcgg acttcttgta ctcggaactg 3528961 gcggctatgc atactactta tggcataaag cagcttcaac cgtggcaagt attcatgaaa 3529021 gcattgataa atctaaaaag agggataaag aggtcagtat caataaaaaa gatccttttt 3529081 ccgtcttaat catgggtgtg gatgaacgcg acggcgataa gggccgtgcc gatacgctca 3529141 tttatatgac cgttaaccca aaaacgaata caaccgacat ggtcagcatt ccgcgtgaca 3529201 cgtatacaaa aattatcgga aaaggcacaa tggataaaat caaccattca tacgctttcg 3529261 gcggcacaca gatgacggta gacactgttg agaacttcct cgatgttccg gttgattatt 3529321 ttgtgaaagt gaacatggaa agctttagag acgttgttga tacacttggc ggcattacag 3529381 ttaacagcac attcgcgttc agttatgacg gttattcgtt cggcaaagga gaaatcacgc 3529441 tgaacggaaa agaagcgctc gcttataccc ggatgagaaa agaagatccg agaggcgact 3529501 tcggacgcca ggaccgccag cgccaagtca tccaaggtat tattaataaa ggcgctaata 3529561 tttcttccat cacgaaattc ggagatatgt ttaaagttgt tgaaaataat gtgaaaacga 3529621 acttgacctt cgataacatg tgggatatcc agtccgatta caaaggtgcg cggaaacata 3529681 ttaaacagca cgaactaaaa ggtacaggca cgaaaatcaa tggaatttac tactaccaag 3529741 ctgatgaaag cgccctttcc gatattacaa aagagctgaa ggaaagcctc gaaaagtaaa 3529801 acaaaaagaa gcttcgcaca atgtgcaaag cttctttttt atttgcctgt aaatgaatcc 3529861 ggttgttctt ttcgataccc gtaatgaaac agcaattctt ccacaatccg gcgggaagcc 3529921 tctccatctc catacggatt agaagcctgg gacattttct tgtactcatc aggatcagtt 3529981 aacagctgtt ttgcaagctg ataaatgttt tcctcatccg tacctgcaag tttcagcgtt 3530041 cccgcttcca ctccttcagg ccgttccgtc gtatcacgca gaacaagaac cggtttcccg 3530101 agagatgggg cttcctcctg cacgccgccc gaatcggtca atataaaatg cgatttcgct 3530161 gcaaagttat ggaaatcgat cacctctaaa ggttcaatca gatgcactct gtcagaatca 3530221 ccaaaatgct tatgagccgc ttcccggaca acaggattca ggtgcacagg gtaaacgact 3530281 tgtacatctt caaattcccc tacaattctg cggatggcct taaacatgtt ttccattggc 3530341 tcacccaaat tttcccggcg gtgagcggtc aagagaatca ttttatcctc acccacctga 3530401 tcgagaacag gatgtgagta accatcccta accgttgtgt tgagtgcgtc aatcgctgta 3530461 ttgcccgtta caaaaataga gtcggccttt ttgttttctt ttaataaatt gtctttcgcc 3530521 tggcctgtcg gagcaaaatg caaatcagca atcgcccctg tcatctgtcg attgagctct 3530581 tccggaaacg gggaatactt attccctgta cggagccccg cctccacatg accgacagca 3530641 atttgatggt aaaaagcggc taggcttccg gcaaacgtcg tcgtcgtatc accatggaca 3530701 agcacaatat cgggtttgat atctttaaac aactcatcca atcttacaag tgcgttagac 3530761 gtaatctctg ccagtgtctg ccgctccttc ataatgttca aatcgaagtc aggcttgatg 3530821 tgaaacgcat ctaacacctg atcgagcatc tgtctgtgct gtgcagttac cgttacatag 3530881 gaatctattt caggatattt tttcaattca agcacaagcg gtgccatctt gatcgcttca 3530941 ggcctggtcc cgaaaacggt catcactttt agttttttca tatttgtcac ctggttttct 3531001 gctatagtaa ataaattcat actacatatt ctacatgaaa atgcatcatt ttaaatcatt 3531061 tcattcttga ttcaaataaa atgatataag ttttaatatt aaggataaag cttgtttaaa 3531121 aatggtttat ccgatatcat aaaaatgtgt aaaaacatat tgaaaagggt aaatagagaa 3531181 tagtttaacc ataaattttt tcgatcataa ggaaggtgcc ttttaaatga aaaaagtacg 3531241 taaagccata attccagcag caggcttagg aacacgtttt cttccggcta cgaaagcaat 3531301 gccgaaagaa atgcttccta tcgttgataa acctaccatt caatacataa ttgaagaagc 3531361 tgttgaagcc ggtattgaag atattattat cgtaacagga aaaagcaagc gtgcgattga 3531421 ggatcatttt gattactctc ctgagcttga aagaaaccta gaagaaaaag gaaaaactga 3531481 gctgcttgaa aaagtgaaaa aggcttctaa cctggctgac attcactata tccgccaaaa 3531541 agaacctaaa ggtctcggac atgctgtctg gtgcgcacgc aactttatcg gcgatgagcc 3531601 gtttgcggta ctgcttggtg acgatattgt tcaggctgaa actccagggt tgcgccaatt 3531661 aatggatgaa tatgaaaaaa cactttcttc tattatcggt gttcagcagg tgcccgaaga 3531721 agaaacacac cgctacggca ttattgaccc gctgacaagt gaaggccgcc gttatcaggt 3531781 gaaaaacttc gttgaaaaac cgcctaaagg cacagcacct tctaatcttg ccatcttagg 3531841 ccgttacgta ttcacgcctg agatcttcat gtatttagaa gagcagcagg ttggcgccgg 3531901 cggagaaatt cagctcacag acgccattca aaagctgaat gaaattcaaa gagtgtttgc 3531961 ttacgatttt gaaggcaagc gttatgatgt tggtgaaaag ctcggcttta tcacaacaac 3532021 tcttgaattt gcgatgcagg ataaagagct tcgcgatcag ctcgttccat ttatggaagg 3532081 tttactaaac aaagaagaaa tctaaacaaa aaggctattg gacattcatc caatagcctt 3532141 tttttatttc aacatcaaag tcaatgtatg ctcttcatta tcaactgcga agacctgatc 3532201 aacggcctgc cgcaaaaatt aataatccca gacaaacaca ctgattgtag agttaaacaa 3532261 actaaatgaa aacataaata caaacatgca gattaaatag taaatatctt gtattcaatg 3532321 caagctaagt aaacaccact tgctaaaaga acaatgacta aacaaccagc attacaaaat 3532381 aattaaataa atttgaagca attacaacag aaggcagtga actgtcggaa agttcatttt 3532441 ggctaccata ttaatccctt taactacgct gttggattta tcaagaattg tcgggctaat 3532501 agaaaaccac ggaatcaaac cagccagcat tcaaacgata aaaggcactt ctccgatacc 3532561 tgttatgacc agcttactgt tgcgcatccc aaatacaaac cagtacgcca tcattagaat 3532621 aaggggattt aaaacctgcc ataatacacc aaaataattg attttttgga tctttcggtt 3532681 aaagaaattt aaaagtacca gtgaatattg taacaaatgt tgagtttttt tcacttttaa 3532741 aaagtaaaga gaagtctcgc agaacttctc ccaacatttg aagtgtcaat ataaaacaaa 3532801 ccaacctcat ttagcaactt tattattatc taattccaaa atagcattat aaatacgatt 3532861 cctattattt ttatcagtat atgcaaaaaa gttatctact ctttttctat acttatcttc 3532921 catacgacta ttgtttttca tataatagat aactttatcc actaagctat tatgattttc 3532981 taatacatca ccaaacccca tttttttata atcataataa tcaagtttaa aatggtatga 3533041 cttttcgtat tgataataaa taacaggttt tttctcatat gcaaaatcaa acgcaacaga 3533101 tgaaaaatca gtaatcatta tattagaaga attaaatagc atttgatagc tgctgttata 3533161 gtcggcaaac tccacataat catgcttttc aaagtctaca atctgttgct gaatatctgg 3533221 gtgaggaaaa aaagttattt tataattatt tttcttagca aattcgatta gccgttcatc 3533281 attaatcaaa gcattatacc tagaaaaata ttcactatct ttaaatttcg ggttgtacgg 3533341 tcttactcct tttgcctgat ctttcggtaa tacaatatct tttctccaag tcggcattat 3533401 tagaagttgc ttttctccct cactcttctt aagattatcg tatctcggaa atccacccaa 3533461 caaaatattc tcttttttat agttgtaatt ccctttcaca atagaccgat attcaggttt 3533521 ggcagaagtg actaataatt tgatattctt gttgtatttg tttaaccatt cagaatgatc 3533581 tgccattgtt attccgtgct gtaaaaagat aaactcaaag ttaaataaat ctctaaaata 3533641 aatctccata ttaaaaaatg gatttacaac ccatatatct gcatgtgtcg atattacttt 3533701 ggaagaggat aaggttaaaa ttttatgtct aaaagatctg tatggtatga cctttccata 3533761 ttttttgatt ctgtcgtaat ccttgctatc tttttttatt ataaagtatt tttttacccc 3533821 atcattcttg ttgattgcat atttaaagag gtgctcggca ttatcatcag ctttgtcttg 3533881 tctgtctatg aataaccata ctggttttct attaaaaata gtgaaaacat ggtgtaccat 3533941 tcttgccatc agtgccttct taatcgctga ttttcgtttt tttgattttt cccctgattt 3534001 atgtagggat tttaagaaac gaaactcttt tataaatcta tttttaaaat tgtttttttt 3534061 gaacattaat tttttataat tataataaaa aatataatct tttttagcca cataagtatt 3534121 atataaatcg tttgacaaac ctgaatactt gaaaaaacga agttttgtca acttcctttt 3534181 tttaccctta gttataaaaa actcaatatg atgattatct gctagatgac ctttgggaat 3534241 atctattgaa aaaccgggat atttttttat tacttctcct aaacttatat aatcattatg 3534301 ctgtcttttt atattctttg cttttatttt tgtttcgcca attttagcat aaaacttaaa 3534361 acctttagaa ttaaacagcg agctccaaaa gccttctatg tgaatggaat cctcattttc 3534421 ttctaaaatt tcaatagtta aagtttgatc cgataatttc gaaacaattt taccttctct 3534481 gtataaataa taatcctgtt cagtttctct ttcatataca tacctactat aattttcacc 3534541 gtgctttatt tttaaagcat gatataaata gaaatggctg acactttttg tttcaatgat 3534601 gacatcgtcg tcaatatacg acaatacttc tcgaatcaat gttaaaaatt cactgtattc 3534661 attttcgtct aaaggtgttt cactgatatc cttaatcaat aatttccact tcaaatcatg 3534721 cataaccata tattgaagaa ataaaggtat tttctgttca tgatttttta taatatcgat 3534781 taaattcttt gagaaagtga taagtgaatg gttaaaccaa ttcttatttg ctttagcagt 3534841 ctgcatggca gatgatccat cttctctaac tctataatgg tattttgcct ctttaaccag 3534901 accatacttt ttcttttgcg atatgattaa attaactagt ttggcatctt cacctatttt 3534961 acaattttca tcaaacctga tatttttcaa ggcatctttt tttataaatg tagaacaaca 3535021 atgagttaat atatgatgcg gttctttttc tacatccaaa attcttgtag aagaaaactt 3535081 attatttaga ttatgttctc cagttcttcc ttctgcaaaa aaaataggga ttgctacaat 3535141 atcaatttca ttcttatgtt cgtcaaagaa gtttaaaaca ttttcgaatg ttccttctga 3535201 aactaaatca tccggatcca aaaattgaat atatctacct tcagcatact ttaaaccata 3535261 atttcgagca ctgctcactc cgccattctg tttctttgca tagacaatgt tattgggata 3535321 tttctgagca tattctttac aaatgatttc acttttatcg gggctatcat cattcaccag 3535381 tattaactga atattctcaa aaccaatagt ttggttaatg atactttcta tagcttcagt 3535441 gagatacaac tcaacattat aaatcggcat tataacactg aaatcatagt taaaactttt 3535501 ttcgttcata aaagattact cctaacataa tgtttatatg aataagaatt cgggtaaata 3535561 aaattaagaa acaagagagt actaattttt gcaaaacaat tttaatttag taaaatgtat 3535621 gaaaagcatt ccttaccttt ttttaaaaac ccttgtaagc aaacttttaa aaatgttcac 3535681 atggttaagt tctaaagaat catttggtgt ttttagtaca aagtcaaatg caaaggccca 3535741 aatcggtatt tcgacaacaa aaccagcata tctaaaatct cttaatttat atccccatac 3535801 ttcaattgtt tttttcagtt cttttcgttt gcattttttt aatcttttaa aatattttat 3535861 atatattctg tcattttctt tcatctcata atactggtta ataaagtgcc ctgttaattc 3535921 aagtctaagc ccttttattt ttgccgaagt aacagtacat gaactatgca gtactctttc 3535981 tttttttata ttttcaagag cttctgtatt ttcttttaat aagtgaaaca taaattcttt 3536041 atagtacatc ggcatatctt gttcttttat aaattgcggg tcaataaatt ttaaaacttt 3536101 aataaaatca tcaacaaaaa ctctttgttc ttgttgatct aaaacagact tataaacatc 3536161 tctatagttc ggatataaaa acagttttat atgatataca attaaaaatt gcaaataagg 3536221 caaaactata tcatatttgt tgaatgaatc catcaacaaa gtcatgtaac attcattcaa 3536281 caaatatgtg tacctttttt tgttaaacca tgaacgatca actaaagaat cctgttcttt 3536341 ccgttttcta taaaaatact ttccttctgc aactgctccg tatctttttt ctttcagtaa 3536401 taactggtta aaaaagatag cgtcttccca aaactttata gattcatcaa aaaggacggt 3536461 actagttagt gtatgtcttc tgtaaaaagt gccgccaata taaaaatgaa tagctttata 3536521 atcgttgaga atatttataa ctcttgttcc tttttcaaat ctattattta atttatgtcc 3536581 cccttctttt tcacctgtgt aataaacagg taataccgca atatttacat gttcggaatc 3536641 acaaaaaaaa tcataaacac tttgcagcgc attttgagag aatgcatcgt cagaatcaag 3536701 aaaaccaata aatttagatc tttcgcttac atttgataat ccacaatttc ttgcagcaga 3536761 aggtccagag ttttcaattt tcatgatttt aatattatta ggatatagat ttttaaagga 3536821 ttcacaaatt tgaggactgc tgtcaacact accatcatct attaatatca gttctatatt 3536881 ttccttaaat ccaattgact ggttaaggac actctctatt gaatatctta aataattttc 3536941 agaattatat attggtataa ttatagaaaa catgtttgta cctctttatt tagaagttaa 3537001 aggatcgttt caattactct tttagaagcc ttgcctcttc taaattacaa aatttattat 3537061 aaaaatcctc atagttatga tctatataag gattatgtaa caactctttt accgtatcta 3537121 taagttcttc acttgtttga agcaagtttc ctggcgtttt ttgctgaaaa ttaaagtaaa 3537181 aacctctgat acagtctcta taagccggga gatcatacac aaaaaataca aggttttttt 3537241 aaaaattcat attatcaaaa aagacagaag aataatccat aatcaataaa tcactaatta 3537301 aatataaatc tcgaatatct ttatttaaag aaacatcgtt cacaaaatat ttatatttcc 3537361 ctaattaaat tgttctgaaa ctggataata ccattcttac aagaataacc atagagtctc 3537421 caaggttccc tcttcatttc ctctaatcaa attaaagtta aatttatact ggccagcttt 3537481 cttaaaattc attatcccgc aaagttggtg catataaaat tatttttctt taattcctta 3537541 tttgataatg tagaattggt aggggattgt agctaaactg tttccagaat agctttcaaa 3537601 taaaattaat ttattgtttc ttggcagaag gacaaaaatt ttaaacaaaa ctgaataaac 3537661 tctaactagt aaacttctgc aattggttat aataaaaatt tcatcagtga actccttaaa 3537721 gagtgaagat taatatttac gcaaacaaga aaaaaagaag caactgaatt tacttcaagc 3537781 ctcttttagt tagtgcttct ataaactagc catatctttt ctgatttggg tagttgaaat 3537841 gcctgctatt cttgtaaggt aaatggcctc atagtattcc tttgtagaca atcgtacgat 3537901 taagtaatcc caggttcttt tgctctttcc agtagcttca tatgtccata gtgaaataaa 3537961 tcaaacattc cgtacgtatc actttcttca ttagataaca tcaccttcca accttttcca 3538021 acttagaaaa aacaaaaatc cttaactgat tgtttatcat ttcgacatat tttttacgtt 3538081 ccattaataa taaacaataa tagcatatgt tcctataaaa gttaaggctc tttaaaaatg 3538141 taaatcatca gcactttttg acaatatcgt tgcattgatg tgtatttttt acagatctga 3538201 tatcttatct atactcatta caacaagttt tctattccgg aagagtcaat tctttttgtc 3538261 gcgttttcaa gtgtaatgat tttctttctg ctgcgtcatt tattttgtac gccctcctca 3538321 tattacttca tcgtcaaaac gtgaaggaat tgtaatacgt agttcctaaa aattttcgtg 3538381 gtaaaattta gtgaagtctt tatcaggcta agggacttta tctaaactac gaattacata 3538441 tggagatata tagatgaaaa ggagggttga tatgatataa acgaaaatca attagataaa 3538501 ggaaaaactg aacacttctg aaaaaagtga taagtttctt tcactatatc ctccaaaaag 3538561 aacctaaagg tcttggacat gctgtctggt tcgcgcctaa ctttatcggc gatgagccgt 3538621 ttgcgtttct gcttggagac gatattgttc aggctgacac accagggttg cgccaattaa 3538681 cggatgaata tgaaagaaca ctttcttcta ttatcggtgt tcagcaagtg cctgaagatg 3538741 aaacacactg ttatggcatc atcgccccgc tgacaagtga aggccgccgt tatcaggtga 3538801 aaaacttcat tgaaaaaccg cctaaagaca cagcaccttc taatcttgcc atcttaggcc 3538861 gttacgtatt cacgcctgag attttcatgt atttagagga gcagcaggtt ggcgccggcg 3538921 gagaaattca gcttacagac gccattcaaa aactgaatga aattcaaaga gtgtttgctt 3538981 acgattttga aggcaagcgt tatgatgttg gtgaaaagct cggcttcatc acaacaactc 3539041 ttgaatttgc gatgcaggat aaagagcttc gcgatcagct cgttccattt atggaaggtt 3539101 tactaaacaa agaagaaatc taaacaaaaa ggctattgga cattcatcca atagcctttt 3539161 tttatttcaa catcaaagtc agtgtatgct cttcattatc aactgcaaaa acctgatcat 3539221 ctgtattcac aagaaaacgc ttcttgctgc tgtcatacaa tacatcgcta tcacttaagg 3539281 atagtgacgc cgggttgata ggagaaatgt tatgaaaaat aagctctgtt gctttatcat 3539341 tctccagtac ataactgatt ttttcataat caaaattcag cgtttttctg ccgtcagcct 3539401 tatttccttc agtataacca ttcaatttcg attgaatgct ggtgctgctg tctcctagga 3539461 atttcagaaa gtattcatag gaagatgctg cgttttgcga gacataagac gtaaatgcag 3539521 tggcatgcaa ttcagcgtgt ttcatgttag ttgcaacagc gctctgtttc acataataag 3539581 agtgcccgtc aaactttatt ttcgctgctt gtttgccttt tgcagctacc gttacttttg 3539641 taccgaatgg cagtgtaacg tcagccttct gtttcaaacc ctgatcctta taagcagccg 3539701 ctttttcatt tgctataaac ccttgcttat tgattgcagt taagcgttcc tctgacttgc 3539761 cctttgcatc gccatgatgg ttcttcactt cattttgcgg aatagcgcca aacgaagcaa 3539821 ttgtacgaag cggggcatta aagaacatcg ttcccgccat gaagacagtc agaatagaca 3539881 aaatagcaat ttgaatggca ttggccagtg atttcggctt tttcttcttt ttgcggaaac 3539941 gggcaaacgc ttcaggatct tctttcttcc tctcttctgt ctgctctttt ttatatgtct 3540001 ctttttcttt tttcgatagc ttattaaacc agtcaataaa cgctttgtac tctttcacaa 3540061 ccgtttttgt ttcatcaaac atacgaagct cgccatagtg catccaagca acacggtcac 3540121 acatcttttc aatctgaccg attgagtggc tgacaaagaa aatcgttttt ccttgctttt 3540181 taaactcatt tattctgtct acacacttct gataaaacgt ttggtccccc acagaaagag 3540241 cttcgtcaat aattaaaatg tcaggatcaa tatgcacgga gatcgcgaaa ccgagacgcg 3540301 acttcatccc gctggaatag tttttaaccg gctgattaat aaaatcgcca atctcggcaa 3540361 attcaacgat gctgtcatac atatcatcaa tttctttatt ggttaacccc atcatcaaac 3540421 acttgagccg gacattgtcc cggcccgtta attggttatt caaaccggca gcaatcgcaa 3540481 tcagcgacgg ctggccgttc atttcaattt caccgctggt cggcggaata attttagcca 3540541 gcaggttaga catggtcgat tttcctgacc cgtttattcc tacaaagccg attgtctccc 3540601 cttcatacac gtcaaaggag acattccgca cagcaaaaaa accattatcc ttagccggaa 3540661 aaaacaatcc tttaatcttg tccgattgtt ttttatacaa atgatactgc tttgaaacat 3540721 ttcgaaacga aacttttagt ttcatcgtaa aatctcctta cgtattaaag aaagtcaaca 3540781 aacttgtctc tgaatttcat atgcaggata gaacctacta acaataaaag gaatgtgaac 3540841 aaccaaaagt acagcgtgta cttcatgtca tggaaaaacc atgctccatc taagaagctg 3540901 ttccggaatc cttcaataat atagaatagt ggattcaact tcagaacagg cactaattcg 3540961 gggtggcttt gaccgagttt cgcattaaca tcccaaaaaa ttggcaacaa gaaaaacaaa 3541021 agtcttgtta cggcctgcag caaaaattga taatctctaa tcagcacact gatcgttgag 3541081 ttaaacaaac taaacgaaaa cataaaagca atcatacaga tgaagtaata aatatattgt 3541141 aaccaatgca cactcgggaa cacaccatta actaggagta caatgatata aatcaccatc 3541201 atgatcatat aactaaataa gttagatgca attgccacgg acggtagaga actaatcggg 3541261 aagttcattt tagccaccat attaatgcgc ttaaatacac tatttgatcc atcaagtata 3541321 gttggactga tgaaaaacca tgggattaat cctgccagca tccaaataat aaaaggcact 3541381 tcgcccgctc cggttgtcac aggaccgccc tttctaatcc ccataccaaa tacgaaccag 3541441 taggccagca tttggataag cggatttaag aactgccata agacacctaa ataattcatt 3541501 tgatatttag acttggtttc ataagccgcc aatcttaaaa ttaaaggaaa tgacgttatt 3541561 tgctctctga gtatacgcaa caaatcattc attttttatc ttccttagac ttaattgttt 3541621 ttgggaatct ttctgtttaa aatttgaaag caccgctgat tattgtaaca gatcctgcat 3541681 tttttttcac ttctcaacaa gtatctaaaa agctgccgaa aaatcgacag ctatacattt 3541741 tataaaataa cctaaattat tcagctttaa atacagtatt aacaaccttt tcagatgaac 3541801 gtcctgactc taaatagcaa aacttatcat agaaaggacc aaaagaaacc ggaagcttat 3541861 aatcaggcga tgagatctgc ttgatagcct caatcgtttc ttcagtagtt tttaccaaag 3541921 gaccaggagc ttctttttca aaatcaaagt agaaaccacg caacttgtcc cggtaggttt 3541981 cgatgtcagg gacaaagaat agcattggcc gttttaaatt tgcaaaatca aagaatactg 3542041 aagaataatc agtaatcagc aaatcagaaa ccatatacaa ttctcgaata tcctcataag 3542101 cagaaaaatc atatgcaaat ccttcaaaag gacctaaatc aaaattctca gctaccagat 3542161 aatgcattct taagattaca atatattcat ttccaagttc ttgtctaagt tgatgcaaat 3542221 ctaaatcgag atcgaactta taacgccctt ttgcatagaa ctgatcatct ctccatgtag 3542281 gggcatataa aataaccttt ttatcacgag gaatatttaa cctactcttt atcaatgata 3542341 ttgtttcctc attattatca ttatgaagaa aatcatttct aggatatcca gattcaatca 3542401 ttgtcttgtt aaactgaaac gcccgtgtaa agatctcagt tgaataacca tttggggaaa 3542461 tcaagtaatc ccaattagaa gcttccttga taaaattcct tttatatttt ttggtgtttg 3542521 taccaggcat atggacttct tccatatcca ttgcaagtct ttttaaaggt gtgccatgcc 3542581 atgtttgtaa atatgttgta tgactaggtt tcggaatcca taatggaagc cggctgttaa 3542641 caacccaata ctcagctctt gccatagcga agagccattt taatgagagg cgattaatgt 3542701 aaggaattcc cttttcatca aaaggcgctg aatattgttt atttacactc caatacattt 3542761 tatactcagg gtggttttcc cgcatatatt cgtaaatcgc tctcggatta caactgtatt 3542821 gtttcccatt aaaactttca aaaatgactg ttttcctttt aactggcatt ctgctagcca 3542881 tcatgaatag agatttgtat gttttagtga ttaacttgtt tctcattttt gtgatctttt 3542941 ttatttttga tactaatctc ttcttctttc ctttaataaa gtatttcatc cttgttttca 3543001 ggctatagtc gtttactctg atacctagag tctgcttttt ctttttctta aagacttcat 3543061 aacgaactgg tgcgttgttt gttttaataa tacttactaa tccttttaat ttgttttttc 3543121 gatctcctaa aacaagagca gtgctgttga actgaatatc cgttccttca tcgtcattgc 3543181 atatatactc cataaaaaga cgataaacat aacgtttttc atttgagaaa ggaatttctt 3543241 tcaaaggcac tttcacttca aaatcataca gttccggaac aaaaccatct gctctcatgt 3543301 tttccaggcc atgtgttttt ctttctagct tgattggaaa tttttcctca ataggtgttt 3543361 ctccaccctt ttttaaaata aggttcaagt tttttatccg atattgattt tcggaactca 3543421 ggtaccccgc ataacctgtt atgcttattt cttcagagct aatctcgatt tgatcaaatc 3543481 tgatgatttt ggcctctctt ttcaccttaa tagaaaagtt gcctttatca gttgtataag 3543541 gtaaaatcaa aagttctgtg gtttgatcga catgaaaggc gcgctcaatt gaatttactt 3543601 cagcagaaag acgcttcaag agtggttcct gctccgcatc ttcatatttt tttcgaaatt 3543661 cgacataaaa atcatatgtt tgtcccattt caacaggcat aggcaaaaca tgagcattta 3543721 tctcagtttt atactctaat gagccagtgt tttgaagcgg aaattcagat tccgttcctg 3543781 aacgtctctc tttcagcttt aaaaataact ggtaatcctc taaaaattgg tgttctgaat 3543841 caattgagat taacaattca agacttccta aattgttttt caagcttttc aaaatacatt 3543901 taatcacagt gttttcaatc attacttttt tctgctcctc tgtataaaag ctctttcctt 3543961 tttgcttcct tttattagtg tcaactacta aggacattaa ctctctttta tttccgtgac 3544021 cctccaagag aaattgcctt taactgttgt atagggctct actctatagc cattattagt 3544081 atctatactg tttcctgaca attttgtttc ttcactcgaa agtcttcgca ttgttttaat 3544141 atggccattt gcattgaaaa caatataaaa atcaataact tgggttttat tagcagctat 3544201 cttttcaata tttacatctt tttcgagatc aattacaaac agttgatcat tttgtaagtt 3544261 tgttgaaata atttcagcct tattctttct gtccaagccc actaaacgta tttttttaat 3544321 atcattatga tcaaaattct caatgtcaat ttctatttta gttttatcaa aatcctcagt 3544381 ataggaacta atagaaggat ctttttttcc aaccttttta gagaacttct ctctttctat 3544441 tcgcacctca atcatctgat taagagcaaa agcccaattt tcaatatagt tgggtcttga 3544501 atatttttca gccattttaa aagcttgttc tgaaaatttt tgatgagtac tttcatcttt 3544561 catcaaagag ataatagctt gacccaattt ctctatatta tactgttcaa tgacatatcc 3544621 atttgctccg tcagtaacta agctccttgc tccgtaatca taatcgtatg ttacaactgg 3544681 acatccattg ctcagtgcct ccatatttga tagaccgaac ccttcaaaat gagaggttga 3544741 aatggttagc caagcttttt gaaactctga gtcagggtta tccgtatagc ctttcaaaaa 3544801 gacattgttc tgcagtttgg tatcttcaat ttcttttttt attttttcga aatcttcacc 3544861 cgatccgaat atatcaagtt ttgcttcagg aatttctttc acgactaaac taaatgcttt 3544921 tactgcatgt atcagatttt tcatagatgc aagtcttgaa ataatgacag ctttgtattt 3544981 ttcactcggc acattcaata cagcgggatc aagaggctta tcaattgtat gcggagtaaa 3545041 gaaaaacgtc tcttgttccc ctgaaatcaa tttaaaatct tctagctgct cctcagttat 3545101 aaaaaagaca gcatccaaat tatacatctg actaaatact tctttatagc gacccttaat 3545161 ttgatattta ttgctgccgt aatgcttgtt atgaataatt gctccataat aggaagaagg 3545221 tgattttttc actttaaaga catgtttgtc ttgcggtctg ctgtccacta aaaacaactt 3545281 aggtttatca ttttgttttt gcagatattc tatccaatat tgacgcagtt ccgattcatc 3545341 ttttactttt atctcaccct caagggagta ccaaataata tgagataatt gaacatcttt 3545401 ttcttcattg ttccatacat agagtttgtc taaatatact tgattttggt cattaatata 3545461 ttcctgcaga tacatcttgt ttagctgcac atcataatga gtaacgagaa ctaagtttcc 3545521 gttcttcgta tattcctctc tctttatgag ctggttttta tcattccaat agtcgacgta 3545581 ccggatagtt tctccatctc cgtagtaaac tacagacatt tcattgttct tcttaccaaa 3545641 caatctcaac agagtttttg caaatttccc cattccaact tgctttttta tctggtcaag 3545701 gcctatcctt tcttcgtatg atcttttccc atttgttcta acacttaaaa aatcatcgaa 3545761 tagattaata acacttgtga attttttatc aatcttaccg ttgctgtaca attcatcaat 3545821 ttttgaagac aactctaaat caaaacgaaa cgttaagaaa aaggtgtttt ggttacactc 3545881 ttctccaaat aattttgaac gcaataataa tgatttcgtc agaccgccat aattacttgg 3545941 cagtccacca gagataaaat aataatccat gtcaggaatt tgttttatat tagattcact 3546001 caccgcatgt aaagacaatt ttttactccc tttcggcatc tagaatatat gatcattgaa 3546061 atttatatct acccggatac tttagtcaca aaaatcaatg taagcatcaa aaagtacttc 3546121 ttatttcaat aagaagtact ttaattagat attgaaccaa tgatatcagg atcctaaatt 3546181 ataaaccagc aatttcctct ttgatctttg ttgtagagat gccttctgtt cttgggaggt 3546241 aaacaacctc acactgatct ttgagaaagt caaatttacc ttcccagtca tcccccataa 3546301 caaaaacatc aatattatga tcaataatat cttgcttttt ttgctcccaa ttcttttcag 3546361 gaattacttc gtccacatat cgaatggttt ctaaaattaa tttacggtgc tcatagctgt 3546421 gataagcttt tttttgcttt tgtaaattga attcatccgt tgaaatagca acaactaaat 3546481 aatcaccaag ctgctttgca cgctcaagca atttaatgtg accccaatgc agtaaatcaa 3546541 aagttccata tgtgataact tttttcattt aaagaaacgc tccttcctaa tgttaaacac 3546601 tattaaaaac actactgacg ttagcgatta aattctaaaa acctgtttgt attccttata 3546661 tcgacatatt tctcgtatgt cttcactgat cattaattat agcataccgc ctaaaaaagg 3546721 ttaagtactc atgaggagaa aaacattcca aaatatgtaa ttacactcag actccattgg 3546781 caccaaggtc tgttgttcat tcgttcattc aattgtaaaa ttggaaacat atttaaattt 3546841 aatgtaaaga taatgttaat cctttgttga agatttatgt taaaatataa ggtagcttga 3546901 ttttgctttt agaaactctc ggtttttaac tatataaata gaatcttaaa ggaaggagga 3546961 gccagacatg caaacagaga ctattcacaa tattccttat gttaacagta acttaacatc 3547021 atttatcgat tacctagaga aacattatat tgatcaaaag attggtgctg tcatttccac 3547081 agtcaaccct gaaattgcat ttgcagctat taaagatcgg gactactttg atgtactatc 3547141 ttcttcaaac ttcattttgc ctgatgggat cggtgtagtc atgatgtcac gtttgactaa 3547201 caacaggctt cagtcccgaa tcgcaggtta cgatgttttt aaagaacttc tgggcgttgc 3547261 taacaaaaag aaaaaacgca tatttctgta cggtgcgaag aaagatgtta taaaaggtgt 3547321 tgtatccaaa atttcttctg aatacccaaa cattaaaatc gcaggttatt cagacggtta 3547381 tgttcaagat cgcaccctag tggcaaaaca aattgcaaga gcaaatcctg acatggtatt 3547441 cgtagcttta gggtatcctc atcaagagaa attcattcat aactacagac acttgttccc 3547501 taaagccgta tctataggtc taggaggaag ctttgatgta tttagcggta atgtcaaacg 3547561 ggccccttcc tggatgatac gtttaaattt agaatggttc taccggttaa tcttgaatcc 3547621 atggcgatgg aaaagaatgc ttagcatccc aaaatatgct ttaacggttt taaaagaaga 3547681 aaaaaacaaa aaaactttct atccaaagcc tgaaaaagat catacaaaac agatttaaaa 3547741 acaaaacttt caaataaatg gatgataaaa atgaaaataa gatcactact ggcgaattgc 3547801 tatttgtatt ttttatcagc aatcgccttt tttctgcaat gggtgaaacc tgaaagcaaa 3547861 gtgaccctcc tgatctcatt cgaagcaaac gcaaaagcga ttcttgagga atatgaacaa 3547921 ggacaatact cttataaact taacatcctg tatacccagc aggcctctgc tattgccgag 3547981 agcttcccga atgtagatgc atatttatta caagaaaaaa accctatcca tctcattaaa 3548041 gctgtatacc taatgtttaa cagtaaagtg atcataacag ataattactt tctattaaca 3548101 agtgtgttaa ataagcggaa gcaaacgaaa tgtatccaag tatggcacgc aaatggctca 3548161 ctcaaaaaat ttggtttgga agacattaca aacatgcaac ggacgaaaac tgatattaaa 3548221 aggttccaaa aagtatacag ttcgtatgat tatttaactg ttggctcaga agagatggca 3548281 aatatcttca agaaatcatt tggaataaag gataaccaat tattaaaaat aggtgtacct 3548341 ttaacagacc cttattaccg agaaaacaag aaaaaaattt cagatactct aaacatacaa 3548401 agaaaaaaaa taatcctcta tgcaccgacg tttagagatt ataatatgca atcaattcaa 3548461 ttgcctttta cagaagaaca attaattcat cagttaaaag aagaatatgt tttatttgtt 3548521 aagctgcatc ccgccattca gaacaatatt gatattaaat attccagtga ttatattaaa 3548581 gatgtttcta actatgcctt gtttgatcta ctcatggctg cagacatatt aatcactgac 3548641 tattcttctg ttccctttga attttcgatt ttaaataaac ccattctttt ttatacttac 3548701 gatttaaaac tttatcaaca gaagcgggga ttggttgata attatctttc cataatacct 3548761 ggaagagcct gctatgacag tgaatcatta ataaatgaaa ttcaaacccc atttaattat 3548821 tccaaaataa aagttttttc cgatagatgg aataagtatt ctgatgggaa ttcaagccaa 3548881 aatttattga atttcatcga aaatttaata agctaaatga tgacacttgt tcaaaacaga 3548941 acaagtgttc ttttttctat tgaataccga acgtatgttt gctttaatgt aattagttgc 3549001 ttatggcagc aaataataat agaggtggta aatttatgag aaaaaaagaa ctgtttgatt 3549061 tcaccaacat cacgccaaaa ttatttactg aactacgtgt agcagacaaa accgtacttc 3549121 aatcattcaa tttcgatgag aaaaaccacc aaatttatac aacccaagtc gcaagtggat 3549181 taggaaaaga caacacccaa agctatcgca taactcgtct atctcttgaa ggtttacaat 3549241 tagacagcat gctgttgaaa catggaggtc atggtacaaa tattggaatt gaaaaccgta 3549301 atggcaccat ttatatttgg tctctatacg ataaaccaaa cgaaacagat aaaagtgaat 3549361 tagtttgttt cccatataaa gcaggcgcga ctttagatga aaattctaaa gaacttcagc 3549421 gattctcgaa tatgcctttc gatcataggg ttacacctgc tcttgatatg aagaatagac 3549481 agttggcaat tagacaatac gatacaaaaa ataataataa taaacagtgg gtgacaatct 3549541 ttaacctgga cgatgcaata gcaaataaaa acaatcctct ttatactatt aacattcctg 3549601 acgaacttca ttatttacaa ggtttctttt tagatgacgg ttatttatat tggtatacag 3549661 gagatacaaa cagcaaaagc tatccgaatc tcataactgt atttgattcc gataataaaa 3549721 tagtgctgca aaaagaaatt actgttggca aagacttgtc caccagatat gagaataact 3549781 tccgtgaacc ggaagggatc tgtatgtaca ccaatcctga aactggggca aaatcattaa 3549841 tggtgggaat tacaagtgga aaagaaggaa atcgtataag cagaatttat gcataccatt 3549901 cttatgaaaa cttcatgaat catgtaccta tgcttcgatc ccctttatta aaaaccgtgg 3549961 ggcaccaaga tacacctcca gaaagatttc aaccatttat tcaaaccttc attttagagt 3550021 ataatgctca aaacaaaaaa tggatggttc cgacttcagg ttatttacca tcttacacat 3550081 caaatttagt ccgaaatatt actatcaatg cagatggaaa cttgcaagtc acattaaatg 3550141 aacgctatat tagtttactg catcaatcga tagaaggaga tttccgctta aaacaaaagg 3550201 atatccgaat gggatcctgg tattttgccg gcggagaaaa atcaaatgtg cttgaaatag 3550261 gttttatgaa agggagtaca aaaatcagac ccgatgatgc agccatctca aatgcttcaa 3550321 gaatgagtat ttttatgatt gttgcggaca agattgaggt gtgataatca aataggctgt 3550381 agctatttaa tagctacagc ctatttgcaa ctttctaagt tttttatcga tattccggaa 3550441 catcaaaata aagtgtataa ccgtccagca atgaatacag gctgtacatg cggtttactt 3550501 gtttgtacgc ccagccgatg tctgttgcgt attgatgtgt cgctgtagct gaccatctca 3550561 ttttgtacag tgtgtcttga ttgtaagctg tgttgtggat atacgatgag cctatgaatt 3550621 tagctccgcc gataatggcc gcttctggtg tgaaccagcc ctgctcgtac gcatatttgg 3550681 ctccgtagta attcggattg ctgtcgtatg ctccaattcc atacatgttg tatacggttt 3550741 ttccgttata ggttaatcca ttggctaaag cggatgtccc gtttcctgtt tccagaagag 3550801 cgtgtgagat taaatacagt tcgttgatgc tatattgatt ggcggcatcg ataaatgcct 3550861 ttgctctccc tgtcaggatg cctttacccg caagcacttt ctgatttacc tcagtaacgc 3550921 tgagacccgc tgtctgtgac agcttgagaa attggaagta gtatttgctg tctctggaaa 3550981 agttattcgg atccacgtat tgaactactt catcactgct tgcgtttcgc cagcccaaat 3551041 tgatcttagc ccagccgttt atctgtccga tgactttcac tttatcgcct tttttaaact 3551101 ggccgatcac gtttgtcggg ctgacttccg gcgttgaccg gatatttagt acatcagccg 3551161 taacagttga tgttgctgta ttaatgtacg tgagcgatac gtaagccgct ccgtctgttt 3551221 gcggacttac tgtcatttgt ttttggacca tatcacgaag cgagagattg tagtttgttt 3551281 tcatgatttg cgggccgttt ttgatcttca cgatagatga tgtccatccg tataattgtt 3551341 ttagcttcgt tgatgccgca gcagctgtat cattgcctgt gaactgctca tttacgctga 3551401 ttttataaag cgtattgctt ttcgttgtat agctcggggt tacacttttc gatttaagat 3551461 aggttaaccc attgttcaat gcggttttgc tgctaagctg tgttgtcacg attttgtatt 3551521 gtgtatatgc agtctggcct gtttttgatg ttgtgactgc gatatgattt tgtttgaaaa 3551581 atgttaaaac gcggtcaatc tcttcttggc tgatgatagc ttcagttgtg atttgatagc 3551641 tgctcgcagc tgtctgaccg gttttctggc ttgctactga tatatgattc gatttgaaaa 3551701 acgtgagtgc ctgattgact ttcgtttgat caagcagaga ttcggttgtg attttaaacg 3551761 tgtcagctat ttgttttttg acggatttcg cagaagcact tagctgattt ttctttaata 3551821 tgttcaaacc ctttgtgact tttgcttgat ctgatgtttc ttctgagatg agctgatatt 3551881 gattttctgc tgttgatcca gctgctgttt ttgcagcttt tacttttttc tgagcaaaga 3551941 aggctgctgc tttgtttgct tgctgctcgc ctaaaatctt tgccgtcgtg atttgataag 3552001 ctgcagacgt tgtcgttttt ttgacgctgg atgacgtgta atgccatttt ttctttttaa 3552061 agaaagtgtc tattttttgg agctgctgtt ttgttatacc cttcatattc acggtatatg 3552121 atgtgctttt tccaacctgt tgataactgc cggatacgcc agtgtttttc ttgatttggc 3552181 tgatggcgtc ctttactgta ctcagccctt tgaaataagc tgattggaca ttgtatgact 3552241 caacggttgt tttttgattg atggacttgt agctgcctgt gatgccagtg ctctgtttca 3552301 gctgctgcaa tagagttttg gcattggctt cacctgaaat ggcggcagtt gtgaacgtat 3552361 aataggcttg ccctttcact gtttccttta atgatgcctg cagcccagat tccttttgga 3552421 aggcgttttt gatctgcgct gctctgctgt ctcccacgat tgtgccagac tgaatggttg 3552481 tgacagacac cgtgtgtgtg atgggctgat acgagctttt aatccccgtt tgcttggcca 3552541 ggctctggat aagcgccttg acttttgtct catcagcaat gtctgatgtc atgacgttca 3552601 tatagggctg agctgctccg taagctttta cagcgccagc cactcccgtc tcctgtttca 3552661 gctttgctag gatagtgttg gcctgttttt ctccggagat ggcacctgac gagatggtga 3552721 catatggctg tttgcttcca acaggacttg acgttcctgt aattgatgtc tgtttggcga 3552781 gtccgctcag tattgctttc gcttctgatt cgctatgaat gcctgaggcg gaaatttggt 3552841 aggtcgttgt tgtgcctgaa gcctgatagg atgcatccca gccagtatct ttttccagtt 3552901 tggcgacagc ttgtgaggct tggctttctg tactgaacgt attcgacggc tctactttat 3552961 atagtgagta gtcggtatac gcggctgcct gggcagaacc agacatggca aaaaaggcaa 3553021 gggacgcggc ggatagaagc ataggtgcga ttagtctctt tttcattcct tctcctcttt 3553081 cttattctat gagtatataa aactagttta tttatcggca cgcgcatgct tcatttatag 3553141 gtgaatcact tccattttct aataaaaaaa cttaacctcg aagtgagatt aagtttaaat 3553201 atgagacacg ataagggtac aagttccttt tatcgtaaaa tcgggcattt gagccggcaa 3553261 aataaagtga tcaccttttt tgagcggaca tgttttgtcc tcatacttga gcaaaccgct 3553321 tccttctatc acgctgcaaa tcagaaagga ttcatcctga gccatttcag cttcgccatt 3553381 gatgtcccat ttataaaccg aaaaatattc cccttggaca aatgttttaa tggttattcc 3553441 ttttcttgat tctgtcgatt catctatata cccgtccaca tggggaaccg tggcggcatt 3553501 gaccgctttg gcaaaatgaa gctctctcgg acttccgttg ctatcaagac ggtcataatc 3553561 gtacacccgg tatgtggcat ctgaattttg ctgagtctct aaaacaaggg cccccttgca 3553621 caatgcgtgc agcgttccgc tcggcacata atagaaatca cccggtttaa ttttgattct 3553681 tcgcagcagg ccctcccagt caccgctgtt gatcattgtg acaagttcgg tttttgagcg 3553741 ggccgtatgc ccgtaaatga tttctgcgtt ttccttacag tcgataatgt accagcattc 3553801 cgtcttgccg agttctccct cttcgttttc tccggcatag taatcatcag ggtgaacttt 3553861 aattgacgta tcttccttca catccagcag ctttgtcaga agcggaaacc gatccccctc 3553921 tacgccgccg aatacttcac ggtgctcttc ccaaagctcg atcaatgtct ttcctttata 3553981 cgggccattt gcaacagtgc tcggtccttt tggatgagcg gaaatggccc agcattcccc 3554041 cgttgattct gaaggaatac tgtatccaaa tctatctcgt aaagcggttc cgccccagat 3554101 tttttcttta aacacaggcg ttagaaaaat cggtgattgc gtcatgatcc gtacccctcc 3554161 cctgtaaata actgatcatc attttcccgg tgcgcccctc ttacaaacgc ccgtataagc 3554221 tgcctttttc ctatgacaac atatgtacaa agcatcatct tttcattacc ccttcaaaga 3554281 aaacgcttcc tatctattat atcacgtcga aaagaagctt tgtttcagcc ttttcctcga 3554341 taagaataat tctccttttt tgatacaaat taataaaaac cgtcaatatg tttaagaagg 3554401 agagaaacta tgcaaatcga ctctgatctc cagaacaatt tagacacact gaaaaaaaca 3554461 ttgggacaaa acgacgatat gatgttttat acatttgctt tcggagatag cagacaaaag 3554521 gcgtgtttac tgtatattga cggtctgaca gagaataaaa tgctggcgca atacgtcatt 3554581 tctcctttac aaaaagaggc gttggcccat aaggaatgct cgattgaaga cttatccgcc 3554641 ttttttttcg gctttcacca cagcgttgtt tctacaatga aagaaataga gcagctcgtt 3554701 ttttcagggc aagccatttt gctcgctgat ggctatcgcg gaggattagc tttcgacaca 3554761 aagtcagtcg caacacgcag tcttgatgaa ccctcctccg aagtcgtgga acgcggccct 3554821 aaaataggat ttattgaaaa gctgcggaca aacacggcgc ttttgcgtga acggacgagt 3554881 gatcctaatc tcgtcatcaa agaaatgaca ctcggaaaaa ggaccaaaaa gaaaatcgct 3554941 gtcgcttata ttcaggatat cgccccagat tatgtcgtca aagaagtgtt taaaaggctg 3555001 aaatcagtca atatagataa tttgccggaa tcggggacgc ttgaacagct gattgaagac 3555061 gaaccatttt caattttccc cacaatatta agcacagaac gaccggaccg ggtcgaaagt 3555121 tctctattag aagggcgagt gtccatatta gtggatggta cgccgtttgc tttgattgta 3555181 ccggctacgg ttgacgaatt tattcattcg cccgatgatt acagccagcg ctggatccca 3555241 atgtcacttg tacgccttct tcgttattcc agcatcctga tcaccattta tttgcccggt 3555301 ctgtatattt ctctcgtttc ttttcacacc gggctattgc cgactagaat ggccatttcc 3555361 attgcaggca gcaggcttaa cgtaccattc ccgccttttg tagaggcctt tatcatgatc 3555421 tttacgatcg aattgattcg agaagccgga ttaaggctgc ctaagccgat tggacagaca 3555481 attggcctta tcggcggcgt tgtcatcgga caggcagctg ttcaggcgca aattgtcagt 3555541 gcgcttatgg tcattgtcgt ttctgtcaca gcactggcat cctttaccgt tccttcatac 3555601 gcctataact ttccgctgcg gatcattcgg atcggggtta tgataagtgc aacagcgctt 3555661 ggcatgtacg gcgttataat ggtttatctg tttgtgatcg gccatctcat gcgcctgaaa 3555721 agctttggcc aggattacat tatcccgatc atggcgcagc ctggacagga tttgaaagac 3555781 acagtcatcc gtattcccac gatgttttta aaaagaagac cgacacgaaa cgatcccgaa 3555841 gataacatca gacaaaggtg atggctatga ggaaatcaga gcataaactg acatttatgc 3555901 agacgctcat tatgatcagc agcacattga ttggtgccgg ggtgctgacc cttccccgct 3555961 cagccgccga aaccggcagt ccgagcggat ggctaatgat actgctccag ggcgttattt 3556021 ttattatcat cgttctgctt tttttgcctt ttcttcaaaa aaacagcgga aaaactcttt 3556081 ttaagctcaa cagcattgta gctggaaaat tcatcggctt tctattgaat ttatatatct 3556141 gtctatattt cattgggatt gtttgctttc aagctcggat tttgggagag gttgtcggat 3556201 tctttttgtt gaaaaatacg ccaatggcag ttgtggtgtt tatatttctt gcagttgcca 3556261 tctatcatgt aggcggaggc gtttattcaa ttgcaaaagt atacgcttat atttttccta 3556321 taacccttat tatttttatg atgcttctga tgttcagctt tcgcttgttc cagcttgatt 3556381 ttatccggcc ggtatttgaa ggaggctatc aaagcttttt ctctttattc ccaaaaacat 3556441 tattatattt ctccggattt gaaatcattt tttacctggt cccctttatg agagatccaa 3556501 agcaagtgaa aaaggctgtt gctctgggca tcgcgacttc cacattgttc tacagcatta 3556561 ctttgctcat tgtgattggc tgtatgactg tggctgaggc aaaaacggtg acatggccga 3556621 ccatttccct tattcacgca ttagaggttc cgggtatttt tattgaacga tttgatttgt 3556681 tcttacagct gacctggaca gcccagcaat ttgcctgtat gctcggatcc tttaaaggcg 3556741 cccatatcgg gttaacggaa atctttcatc taaaaaataa aaacaatgca tggctgctga 3556801 ctgcaatgct ggctgcgacg tttttcataa cgatgtatcc caaggacttg aatgacgtgt 3556861 tttattacgg gacgcttctt ggatatgctt tcttaattgt gattacaatt ccattcttcg 3556921 tctggttttt aagctggata cagaaaaaaa tagggagggg gcagctgcaa tgaaaacagc 3556981 atcaaaattc tccgtcatgt tttttatgct gctggccctc tgcggctgct gggatgtcaa 3557041 agatatcgag caactatcct tcgccagagg gctggcgatc gatgagacaa atgatcacca 3557101 gtacaaactg acgtatcaaa atcttcttcc ccaaagcgaa gacagccaag catccggaaa 3557161 acccgaattt gttaatgtaa cgtcccacgg gaaaacgatt ctggaagcag tcagtgatgt 3557221 atccatcaag gaccctcctg tttatagcga tcatttaaaa gtgatccttc tgggagaaaa 3557281 actgatgagg aatcaaaatg tagaccaagt cctcaaccac tttatccggg atgatgagct 3557341 gcggcgaagc agctatttga tggcagccag agggaatgca gctgatgttt tcacaaaagg 3557401 aaaccccaat cagcagcagc cgatgccctc cgaaaaactg attgatttga caactcacag 3557461 cggatataac ggtaagatta tgataccgct gcgcatcgga agagcttctg tctactctca 3557521 gaacgggtac agttatctta ttcaagccgt gaaaaacgaa aagggaaaag ccaagtatga 3557581 cggagcaggc attatcaaaa ggggcagcaa taaactcgtt gggtttcttt cagctgatga 3557641 aacccaaaca ctgtcatggg tcatggggac gatccaaggc ggtgtcatgc cgacgacaga 3557701 taaaggacat ccgattacgt ttgaaattaa aaagtcgaaa acgaaaatta agcccgtcat 3557761 tgaaaacgga aagcctgtct ttcatatttc tgttaaaacg aagggcatcc tgacagaaga 3557821 ccaaaacccg aatgaaaact cctttagcaa aagttatttg cacaggctgg aaaacatttt 3557881 tgaaaaaaag cttgaacgag atgtaaagca ggtgatggat aaactgcagc acgagtataa 3557941 aaccgatccg gtctttttat cagaccacat aaggattcaa caccctgact actggaataa 3558001 agtaaaaggg cattgggatg aaatattttc tgagactgat tttaagtacg atatttcttt 3558061 taaaatcatt aactttggca cggtgggaaa gtaagcaatc aaaagggtgc gcatgatcgc 3558121 gcaccctttt ttatgttccg acagtctgct gttttccggc cgctcctccc tgtccgtttt 3558181 tgtcccgtaa atcctgctca atttcttcaa ggcttcttcc ctttgtctct gtcactttaa 3558241 atcggacaaa taagaacgcc atgataccga tcgcggcata aatcaggaat aaataactga 3558301 ttccgatcgc ttccattaat attggatagg ttaatgaaac aatcagtgtc ccaacgtgca 3558361 acattaaggt cgaaacaccg gtcccgattc ctctgacgtg aagcgggaac aattcaggaa 3558421 gcatcaccca cacaaccggt ccccagctga ccgcaaagac aacgataaac acgcctaaac 3558481 aaatgacggt cgtccatgag gcagccggag tgttatcgaa aaagagattt actaaagcga 3558541 gaacgatcaa gctgatcacc atgcccgcat tcccgaatag cagtaacggc tttcttccaa 3558601 tcttgtcgat gattttaatc gctactaatg tcatgagaac attgactgtg ccgattccga 3558661 ccgtgcctaa aatcgaagcg gagtttccga atccgacgtt tgtaaaggtc tttggcgcat 3558721 agtagatgat cgtattcgtt ccgataaatt gctgcaaaaa agcgagtccc aaacctgcaa 3558781 taagcgctgg gcgcacccat ggatcgaaca gctccttcag accgccttca tcctgctttt 3558841 ccgcttcttt tatatcatgt atttcctgat caatatcttt tgtgccacgc aatttttcaa 3558901 gaattttctt cgctttgctt tcttcgccat tcgtgaacag ccagcgcggg ctctccggca 3558961 taaacaaaat gccaataagc aagagcaatg acggcacagc agccaatcca agcatccagc 3559021 gccacgcttc ggcatcggca aatatgtaat tgacaatgta agaaagaagg atgccgaccg 3559081 tgatcatcag ctgattcagt gatgacagcg ccccgcgttt atgttttggc gccagttcag 3559141 ataaataaag gggtacgatt gtcgtcgatg ttccgactgc aagtcccaaa atgatgcgaa 3559201 acagcaccat gactcctgta tttggggcca gtgccacacc aagaccgcct atacaaaaca 3559261 gcagcgcggc tgccataatt gctttttttc ttccgaaacg gtcagtcagc ttgccggccg 3559321 ctcctgagcc caatatcgcc ccaaccagca aggagctgac aacaagacct tctgtaaacg 3559381 cgtttaagcc taactccttt ttcataaata aaatagctcc ggaaatcact ccggtatcat 3559441 agccatataa cgcgcctcca agagctccga aaaaataaag ccatatattt gactgctttt 3559501 tcataaagat gactcccttt ctccatcagc tgcaatgaca ttgtctgtgg gattttttta 3559561 gaaatctttt agcctctttt tccggccatt aaaccttttt atttttctga tcataagttt 3559621 tccaatcatt tacttgtatt tttttcaatg tcgccgaaac attttacctg ctgcggcgtc 3559681 caatataagg tgattcagta cattatcgtt atcaattttc aaaaacaaga acttataaat 3559741 ataggaatat ttatcgaaaa atgtctttcg agtagttgcc ccatggcaaa tagaatggta 3559801 cgcttcaaat attaaagaaa cgtgaggtat tgatatatgg aagaacgatc acagcgcaga 3559861 aagaaaaaaa gaaaactaaa aaaatgggtg aaagttgttg ccggattaat ggctttttta 3559921 gtcattgcgg caggctctgt cggcgcctat gcttttgtaa agctgaacaa tgcttctaag 3559981 gaagctcatg tcagccttgc acgcggagaa caatctgtaa aacggatcaa agaatttgat 3560041 cctggaaaag attctttttc tgtattgctc ttaggaattg atgccaggga gaaaaacggc 3560101 gagaccgtcg atcaggcaag aagtgacgcg aatgtgctgg ttacatttaa tcggaaagaa 3560161 aaaacagcta aaatgctgag cattccgcgt gacgcctatg taaacatccc aggccacggg 3560221 tatgataaat tcacacatgc tcacgcttac ggcggcgttg acttaactgt gaaaacagtt 3560281 gaagaaatgc tggatattcc agtcgattat gtcgtagaaa gcaatttcac ggcttttgaa 3560341 gacgtcgtaa acgagttaaa tggcgtcaaa gtaactgtaa aaagcgataa agtcattcag 3560401 caaatcaaaa aagatacaaa aggtaaagtc gttcttcaaa aaggaacaca tacgcttgat 3560461 ggggaagaag cgctcgctta cgtaagaaca cgtaaagcgg acagtgacct tttacgcggg 3560521 caaagacaaa tggaagtgct gagcgccatt atagataaat caaaatcatt gagctcaatt 3560581 ccggcttatg atgatattgt ggatacgatg gggcaaaatt taaaaatgaa cttatctctt 3560641 aaagatgcca tcggcctgtt cccgttcatc acttcattga aatcagttga gtctattcag 3560701 ctgacgggtt atgattatga acctgccgga gtctattatt tcaaattgaa tcagcaaaag 3560761 ctgcaggaag ttaaaaaaga gctgcaaaac gatttaggtg tataatgaac gggatggcga 3560821 ttacgccatc ccgttttaca tatttccttg ttgaaaatta tcaaagtaac gtttagcctt 3560881 aatttatatg gattatgttt cacaggcaag ctgaacatac tacacgaagc agcttcattt 3560941 ttaaggaggt tcccctacat atgaaatgta ttgcgattga tctagacgga acattactga 3561001 ataaagaaag cgtcatttct gcggaaaaca gagaggcgat caagcgggcc gttgatgccg 3561061 gcatcctcgt caccatttgc acgggaagag cgacatttga tgtaaaagcg ctgctggatg 3561121 acttggacat ccctatcatt gcagctaatg gcggtacgat ccacgacacg ggttaccgtt 3561181 tgatcagccg gacattaatg gatcaggaag ccggtaaagc gattgctgat tacttacttt 3561241 caaaaaacat ttactttgag gtatatacag atgaccatct gctttctcct tttgacggcg 3561301 aagctaagct gcacgcggag cttgacattc taaagagcgc aaacccaaac gagcagacgg 3561361 atgacttgtg gcaaggagcc atgactcaat tcaaacagtt tggcattaaa ccaatccctc 3561421 atatcgaatc ggtttttgac ggcggtgaaa acatttataa gcttctttgc ttctcctttg 3561481 atatggacaa gctgaaacaa gcgaaggaag aactgaagca tcataaaaaa ctggcgcaaa 3561541 cctcttcagg aaaacatatt atcgaaatcc tgccggcctc gtcaggaaaa ggacgcgcgt 3561601 taacaaagct ggctgacata tacggaattg aaacacagga tatctatgcg atcggcgata 3561661 gtccaaacga tttgtccatg tttgaagtcg ccggacaccg tatcgccatg gaaaatgcga 3561721 ttgatgaatt aaaagaaaaa agcacctttg tcacaaaaag caatgacgaa aatggtgtgg 3561781 cctactttat agaccagctt ctttcggggc aatatgcata aagaaaagac tccagagatt 3561841 ggagtctttt tcttttattg cacccgtata cttcctgcgt atttatcctt ccaatatgtg 3561901 ctcgtgttca tattggtaat ggtcacgccg tttgataatg tgacatgaac aacttgtccg 3561961 tttccgatat agatggaggg atttaagctt gttgattgaa agaacacaat gtctcccggc 3562021 ttcaggtccg ccttctcaat cttagttccg gcattgtact ggcttgttgc gtatcgaggc 3562081 agggaaatac cggctgcttt ctggtataca tattggacaa atccagctgt atcaaatccc 3562141 gtctcaggtg ttactccgcc ctgtttgtaa ggcacttctc cgacataaag cgtcgcttcg 3562201 gaaacaatcg gattttcttt cgggattgtc aggttgtcaa atcggcgaat acccgtcatc 3562261 ttcgatttcc agtaatcctc tgacaaatag gaaatggtta ctttttctga ccggcttgcc 3562321 tgaatgaacc tgcctgcgcc cgcataaatg cctgcatgtg aaattcccgt tttatacgta 3562381 ttgctgaaat agacgacatc accaggcttt atgttctgag gggctacctt ctcgcccact 3562441 gcccactgct gttcggctga tcgcggtaga taaatgccga gtgcctgttg aaacacatat 3562501 tgcacaagcc ccgagcaatc aaagccctct gacggcgtgc ttccgccaaa cacatatggg 3562561 acaccgatat atttttcggc ctcctgaacg acaggaacat cagccgttgc cggatcggca 3562621 gcgattcgtc tcgccccgat ataagttccg ctccaatagc tgcttttttt gtaattggtg 3562681 atgataaccc cttttgactg tgtactgtga accatttggc cgtctccgat ataaagggcg 3562741 tcatgtgtcg gaacagtgcc ggtgcttccc tctttcttga aaaacaaaat atcacccggc 3562801 ttcaggtttt ccggttttac agctgttccg attttatact ggtcgtttac agatctcggc 3562861 agatgaatat cagccttact gaacacatat tgtatcaatc ctgatggatc gaaaccctct 3562921 ttcggcgttt ccccgccata tttatactga tatccaagca ggttttttgc ttcgctgaca 3562981 atcaattctg atgatgtatc agcttccgca atctccgctt ttgtcataat tggaaccaaa 3563041 aaacaaatga taaccgccac aagcaaaaac ttcttccagt ttgccagtgt gttcactttt 3563101 attatctcct cctctttttg cagttttaac atcggtattt ttttgaatat gttaagagac 3563161 tttttaatat ttttacagaa tgaatatgct gggcaaataa aaagagagtg tctcatcaga 3563221 cactctcttt tttgaattat ttattggcgt ttaccggttc ttcctgctgc tggattttat 3563281 tcatttccat atcaatcttc tgtttttcct gatctgtcag ctgatcattg aatttaaaag 3563341 ctgacataaa catgaacacg atggctacgg caacaaacgg ccagatggct ttgacaaatt 3563401 tcatctttat cactccgatt atttagattt tagtttgtca ctatgatcaa tatcaaacgt 3563461 cagttttccg tcttctactt tccaagcgaa attagagtct ttcgtcagtt cgcgaataat 3563521 ggttttctgt ttaaggctgt cttttttcac aggcgcaggt gtcgcttcat ggatatcgat 3563581 cggtgtcact tcaaagcgtc ctgttccatt tttcttcagg tgatactgaa ccagtgcact 3563641 gtctcttgtt ctcgtccagc cttggtcaaa gacaaagttg ccgaggctgt agaaaatgac 3563701 ggttccgtta tatacttcaa tcggttctaa gacgtgcggg tgatggccga cgatgatgtc 3563761 agctcccgca tcagacatgg ctcttgcaag ctggcgctgg cggtcatttg gatcattgtc 3563821 atactcttgt ccccagtgtg actgcacaac aacaatgtcc gcatgttttt tcgcttctga 3563881 aatcataggg atgaagattt caggatctgc gggcagcacg cccggcgtat tctttttagc 3563941 cgcgaaacct ttcccggaca catcggtaaa gccaagcgtc gcaatcgtta ccccgttgac 3564001 tttctggtac gaaattttct ttttcgcatc acttaagctg tatcccgctc caacgatatc 3564061 aagattttgc ttcgcaaatt ctccaagcgt atctttcatg ccctgaacgc cgtaatccat 3564121 tgcgtggttg ttggcgctgt tgagaaccgt gaaattcata tccttcaaga ctttcactga 3564181 ttccttattc gtctgcagat gaatctcttt atctgcttgt ttataattct tttgataggt 3564241 taccgggttt tcaaagtttc ctgctacata atccgaggct ctaaagatcg gttcaacata 3564301 ttgaaaaata ctgtctgccc ctttttgctc cgttactttt tcaacatagc gtcccatcat 3564361 aatatcgcct acaaatgagg ctgagagtac gtcgtcagaa tacgttttga ccttcggcgt 3564421 ttccgctttt cccgcccaca tgaaagcgaa cataaggaca aaaacgatcg gaatggcaat 3564481 aaatacgtgc ttattggttt tctttttttg ctgttttgtc agctttagca gcttttcatg 3564541 aaagctcagt tcttttttca tcgtttgaca caccttacat taaattaagt agtaaacaaa 3564601 catgatagca aaggtcgctc cgctcaatag cagcgtgctt ccgaacgtaa tggttaaacc 3564661 ttgtttctga atggtattgg caattaaacc tggcacgatg atgccgattc ctcgaaattc 3564721 tgcgatttca aatggtacaa tcgggtatag aaaatcaaac gcgattttta ggacgatccc 3564781 tgttatcagc atggcagcga attttctgcg tccgtacaaa atcataaatt tggataaacc 3564841 gtatttcaca atgacatacg tgagcaagct cactagcaaa acaagtaaaa taaagaccgg 3564901 ctgattaaac acaagtccta aatatcccgg tacaacaagt cctgccggca cgatccctgt 3564961 tttttccgca aaaattaaac tgagtagtac acctaaaatt agtgcgatgt ataaatctga 3565021 tccgaacatg tctgcatttc cccctagctt acgagctgct ttaccttgta ttcgtggatt 3565081 ttttcaatta aaggctctgc ggcaccatga atattgccga cgccatatat gacacggttg 3565141 tgcattcttt tctttaacaa ttccataatt tcatctgttg acttatactc tagatcatgc 3565201 agtttgtctg caggaatttt gccttcttcg taggctttta cgatcggttc tgttgtttca 3565261 ccgattaaga tcagttcact tgcttcaata taaggcaata cgtcatttgc gaattgctgt 3565321 gtccgatcga cacggtctgc gcggcagttc atgatgatga tcggatcatc ggtcgggtaa 3565381 ccgatttctt ttacacgttt ccatatattc aaagtagaag aagcgtcgtt tgcggcaaac 3565441 ccattaacaa agtgcccagg ctcgctcgga ctgatcagcg gaagaattct cattgctccc 3565501 ggatctggcg gcgcattcag cattccctta aatgctgttt cttcgtcaat gccgagtgct 3565561 tgagccacac ccagcgccag agaagcgtta tcagggaata ccatgtattc aaatttacgt 3565621 aaatactcat ctgtaatttt tgagttatca gcaatgatga cttttgtgtt tcgttctttt 3565681 gctttttgtt taaagaactc ggtatattca ctatctgtaa tgacaagatg gccattataa 3565741 ggaattgtag cagtaaacgc ttctgcaatt tcatcaagcg tcggccccat gacatccata 3565801 tggtcttcca aaacattcac aatgacgccg atattggcct gcagaagttc ttcctgaaag 3565861 atgatttgat aatctgggtt aacagccatg cattcactga caatcgcgtt agcccctctt 3565921 tctactgttt ctctcatgac ttctttttgc tctccgatat tcggcccctg aggtttccgt 3565981 ttaatcggct tttcctccgg tgtgtcccag taaatcattc ttgcatctgt tcctgttgtt 3566041 tttccaacag tcttgtaacc ggcttctatt aatattccgg ttgtcagcct tgtcacagtc 3566101 gattttccgc ggatgccgtt aatattcacc cgaacaggga gggcatcaat gtttttctga 3566161 tgtcgtcgtt tttctaatat tccgatgacc agtatgacag cacaggctat aatgagtaac 3566221 cacattgctt ttcgacatct ccttctatat tgttgtaaat tcattcatca gtatatagaa 3566281 tcactatgaa ttctcaatcg gcattatgta acataatctt ccctaatcga ctaagccaaa 3566341 cttctctttt gaaagagatt ttatacctac aaactgtttt ctatttttgg aaaacagcag 3566401 gacttatacc ttatcacttt ttaaaaaaat caaagagaat gcgctttcat ttttctcctg 3566461 atatccttct ggacgtatag tcacaccctg ctgtttgtat ttaatatgca tttcaaatca 3566521 atcttttttt cagcctttgt tatcaagcat ttcctgctat catgcgtgtt tccggttctt 3566581 atgaacacaa aataatttta tcctgtttct taaggacaag gtcataatgt catcctttct 3566641 gcatggaata agcaatatga ggcccattcc aaaatgacta aggaggttcg agatgaaaac 3566701 gctaaacata cgagtccgaa ttctctaaca taattaaaca ttttctggga tgatagtctt 3566761 ttctgtttct ccccatttac aggtctaaac gcatgacttt gaaacaattt taataaaact 3566821 taatatttgt tcaagaaatc ttcatccata tttgtgaaga ctttgtcaaa aaaagagtga 3566881 aaaccttaaa tttttcaatt atatatacaa tttacaatta gatttctttt gatattttta 3566941 ttgctaactt cggattgttc atgataatct atctatgtaa acggttacat aaacaaggag 3567001 gagctgtttt ggctacaatt aaagatgtcg ccggagcggc gggcgtttca gttgcgacgg 3567061 tttcccgcaa cctgaatgat aacggctatg tacacgaaga aacgcgaacg cgtgtcatag 3567121 cggcgatggc gaagctgaac tattacccga atgaagtcgc cagatctcta tataaaagag 3567181 aatcccgact gatcggactt ttgctcccgg atatcacaaa ccctttcttc ccccagcttg 3567241 cccgcggtgc ggaggatgaa ttgaaccggg aaggctatcg ccttattttc ggcaacagtg 3567301 acgaggaatt gaaaaaagaa cttgaatacc ttcaaacctt taagcaaaat catgtcgcag 3567361 gcattattgc cgcaacgaat tacccggatc tcgaggaata cagcggcatg aattatccag 3567421 ttgtttttct ggacagaacg cttgaagggg ctccttctgt gtccagtgac ggctatacag 3567481 gagtaaagtt agccgcccag gctatcattc acggaaaaag ccagcgcatt acgctcttga 3567541 gaggacccgc tcacctgccg accgctcaag accgatttaa cggcgctttg gaaatcttaa 3567601 agcaggctga agttgatttt caggtcattg agacagcttc attttcaatt aaagatgcac 3567661 aatcgatggc gaaggagctg tttgcctctt atccagcgac agatggtgtg atcgcgagta 3567721 atgatattca agccgctgcc gttttacatg aagcattgcg gcgcggaaaa aacgtgccgg 3567781 aggacattca aattatcggc tatgatgaca ttccgcaaag cggacttctg ttcccgccac 3567841 tttctacaat taaacagccc gcatatgata tggggaaaga agctgccaaa ctgcttttgg 3567901 gtatcattaa aaaacagccg ctggcagaaa cggcaattca aatgcctgtc acctatatag 3567961 gaagaaagac gacaagaaag gaagattaag atgcgtaata tttgtgtgat tggtagctgt 3568021 tctatggatt tagtggtcac ctcggacaaa cgcccaaaag ccggtgaaac ggttcttggc 3568081 acgtcatttc agactgtgcc gggcggcaaa ggagcaaatc aggccgttgc cgcagccaga 3568141 cttggggcgc aagtgtttat ggtcggcaaa gttggagacg atcattatgg aacagctatt 3568201 ttgaataatc tcaaagctaa cggcgttcgc actgattata tggaaccggt tacacatacg 3568261 gaaagcggaa ccgctcatat tgtgcttgct gaaggcgaca acagcattgt cgttgtcaaa 3568321 ggcgcgaacg atgacatcac cccagcgtat gcgttaaacg cgctcgaaca gattgaaaag 3568381 gtcgatatgg tgctgattca gcaggaaatc ccagaagaaa cggttgatga ggtgtgcaaa 3568441 tactgccatt ctcacgatat cccgatcata ctaaacccag caccggcccg cccgctcaag 3568501 caggaaacaa ttgatcacgc tacctatctg acgccgaatg aacacgaggc ttcgatttta 3568561 ttccctgagc ttaccatttc cgaagctctg gcgctttatc cggcaaagct ctttattacg 3568621 gaaggaaaac aaggcgtccg ctattcggct ggcagcaaag aggtgctcat cccgtccttc 3568681 cctgtagaac ccgttgatac aaccggagcc ggtgatacgt ttaacgcagc atttgccgtg 3568741 gccctggctg agggaaaaga cattgaagcc gcattgcggt ttgccaatcg tgccgcttcc 3568801 ctttctgtct gctccttcgg tgcccaaggc ggaatgccga caagaaatga agtagaggag 3568861 ctgctgtcat gaaaaaacac ggtatactga acagccatct tgccaagatt ttagccgacc 3568921 ttggccacac tgataaaatt gtcatcgcgg atgccggact gccggttcct gacggcgttt 3568981 tgaaaattga tctttcactg aagccgggcc ttccggcttt ccaagataca gcggcagtac 3569041 tggctgagga aatggcggtc gaaaaagtca ttgctgcagc tgaaataaaa gcatccaatc 3569101 aggagaatgc gaaatttcta gaaaatcttt tctctgaaca agagattgaa tacctttctc 3569161 acgaggagtt taagctgctg acaaaagatg caaaggcagt cataagaaca ggagaattca 3569221 caccatatgc caactgcatc ctgcaggcag gtgtactttt ctagaaagga agatgaaaca 3569281 tgcagattga aatgaaagac attcataaaa cattcggaaa aaatcaggtg ctgtcaggcg 3569341 tttcctttca gctcatgcct ggcgaggttc acgcattaat gggagaaaac ggcgccggca 3569401 agtccacgct tatgaacatt ttgacaggcc tgcacaaagc agataaaggt caaatcagca 3569461 taaacggaaa cgaaacgtat ttttccaatc cgaaagaagc ggaacagcat ggaatagcct 3569521 ttatccatca ggaattgaat atctggccgg aaatgaccgt tcttgagaat ctatttatcg 3569581 gtaaagagat atcctccaag ctgggcgttt tacaaacaag aaaaatgaaa gcgctagcaa 3569641 aagagcaatt tgacaaactt tccgtctctc tttctcttga tcaagaagcc ggcgaatgtt 3569701 ccgtcggaca gcagcaaatg atcgaaattg caaaagcgct tatgacaaat gccgaggtaa 3569761 tcattatgga tgaaccgacc gcagcgttga ctgaacgtga aatcagcaag ctctttgagg 3569821 tcattacagc gttaaaaaag aacggcgtct ccattgtcta tatttcgcat cgcatggaag 3569881 aaatttttgc gatttgcgac agaattacca tcatgcgtga cggaaaaacg gtagatacaa 3569941 caaacatctc agaaactgat tttgatgaag tcgtcaaaaa aatggtcgga cgggagctga 3570001 ctgaacgata tccaaaacgc actccttctc tcggtgacaa agtattcgag gtgaaaaatg 3570061 cttccgtaaa agggagtttt gaggacgtca gcttttatgt gcgttccggt gagatcgtcg 3570121 gtgtttcagg attaatggga gccggccgga cagaaatgat gagagcgctg ttcggcgttg 3570181 acaggctgga cacgggtgag atatggatcg ctgggaaaaa aacggctatt aagaacccgc 3570241 aggaagccgt gaaaaaaggt ctcggcttta ttacagagaa tcgcaaggat gaagggctcc 3570301 tgctcgacac ctcgatccgc gaaaatattg ccctgcccaa tctgtccagc ttctcaccaa 3570361 agggtctcat tgatcataag cgggaggctg aatttgtcga tctgttaatc aagcgcctca 3570421 ctatcaaaac agcatcaccg gaaacgcacg cacgccattt atcaggagga aaccagcaaa 3570481 aagtggtgat agccaagtgg atcggcatcg gaccgaaagt gcttatcttg gatgagccaa 3570541 ccagaggtgt ggatgttggc gccaaacgag agatttatac gctgatgaat gagctgaccg 3570601 aacgcggtgt cgctatcatc atggtgtcat cagagcttcc tgaaattctg ggaatgagcg 3570661 atcggattat cgttgtccat gaaggcagaa tcagcggcga aatccatgcg cgagaagcaa 3570721 cacaagaacg aattatgaca cttgccacgg gagggcggta atatgaaaac ggaacaactg 3570781 caaacagaac aaaaacggat tcacttcgac ggagtcatgc aaaaactcgg cccgtttctt 3570841 ggtttattta ttctcgttat cattgtatct attttaaatc ccagctttct tgaaccgctg 3570901 aatattttaa acctgcttcg ccaggtcgcc attaacggat taatcgcgtt cgggatgacc 3570961 tttgttattt tgacaggcgg cattgatctt tctgttggcg ctattcttgc cctgtccagt 3571021 gctttagttg cggggatgat tgtgtccggt gtcgatccgg ttctcgcgat catccttggc 3571081 tgtatcattg gtgccgtact aggcatgatc aacggattat tgattactaa aggaaaaatg 3571141 gcgcccttta tcgccacgct tgcgaccatg actgtgtttc gcggactgac gctagtgtat 3571201 acagatggaa atccgattac cggacttggc acaaactacg gttttcagat gttcggacgc 3571261 ggttactttt taggcattcc tgtaccggca attacgatgg ttcttgcctt tgtcatcctt 3571321 tgggtgcttc ttcataaaac accattcgga cgccgaacgt acgctatcgg cggcaacgaa 3571381 aaagccgcgc tcatttcagg catcaaagtg acgcgcgtga aagtgatgat ctattcttta 3571441 gccgggcttt tatccgctct tgcaggtgcc atattgactt cccgcctgca ttcggcccag 3571501 ccgactgcgg gagaatcgta cgaacttgat gctatcgcgg cagtcgtctt aggagggaca 3571561 agtctttccg gcggccgagg acgcattgtc ggcacgttaa tcggggtgct gatcatcggc 3571621 acacttaata acggacttaa tctgcttggc gtctcatcat tttatcagct ggttgtcaaa 3571681 gggattgtta tcttaattgc ggtattgtta gaccgcaaga agtcagctta ggagggtttt 3571741 acatgaaaaa ggctgtatcc gtcattttaa cgttatcatt atttttgtta accgcctgtt 3571801 cgcttgagcc tccccaatgg gcaaagccat caaactcggg gaacaaaaag gaattcacca 3571861 ttggcttgtc cgtctcaacg cttaataatc ctttttttgt ctcattaaaa aagggtatcg 3571921 aaaaagaagc taaaaaacgg ggaatgaaag tcatcattgt tgatgcacaa aatgattcat 3571981 cgaaacagac gagtgacgtg gaagatttaa ttcagcaagg tgttgatgca ttattaatca 3572041 acccgactga ttcttcggcg atctcaacgg cagtagaatc tgcaaacgca gtcggtgtgc 3572101 ccgtcgtaac aatcgatcga tctgcggaac aaggaaaagt tgaaaccctc gttgcttccg 3572161 ataatgtaaa aggcggtgaa atggccgcgg cgtttattgc cgacaaactt ggaaaaggag 3572221 caaaggtggc agagcttgaa ggcgtccccg gcgcatctgc cacacgggaa cgcggctcag 3572281 gattccataa catcgcagac caaaagctcc aagttgtcac aaaacaatca gctgactttg 3572341 accgcacgaa aggcctgact gtcatggaaa acctgctgca gggacatcct gatatccaag 3572401 ctgtttttgc tcacaacgat gaaatggcgc tcggtgctct cgaggcaatt aacagctcgg 3572461 ggaaagacat attggtgatc ggttttgacg gcaataaaga tgcgctcgct tccattaaag 3572521 acagaaagct gtcagccacc gtcgctcagc agcctgaatt aatcggtaaa ttggctacag 3572581 aagcagcaga tgatattttg cacgggaaaa aagtgcaaaa aacaatatcc gcgcctctca 3572641 aactagaaac acaaaaataa ttgtctgatg tttaggaacc tgcgataacg tgaatagaga 3572701 tatagaatga attatttctc ttacgtgagg agaggaacgg catgaacaaa ccaacaaaac 3572761 tattttcaac attagcactt gcggctggaa tgactgcggc ggctgctggc ggcgctggca 3572821 cgatccatgc tcaacagcca gaaacaacgg taagcattga tgatttatac agttatccga 3572881 ttgattctta tttggtatca gcagaggctc taaatgtcag aacgaagcct tccgcatcaa 3572941 gccagaaagc cgatacgctg cacttaggag atagcctaaa gctgatttcc ttctcaaatg 3573001 ctgactgggc aaaggttaag tataaaaatg gaaaaacagg atttgtatcc actcattaca 3573061 ttgttaaagc agcgacaacg gtaaaaacca aaacaaaaac aaaagtgtat acatccgctg 3573121 acggaaagag cattaagact cttccagcag acacaagcgt ttctttttta ggctggagta 3573181 aaacgaataa aggcggtttt gattttgatt gggtattcgt tgattacggc ggtacgacag 3573241 gttatatgaa aacaaaggat ttacacatga caaaataact gagagggatt ccgcataaat 3573301 gcggaatccc ttttattatg aattgatttg tcacattccc aagatatttc tcaggaaata 3573361 ttgtcgtatg ctgtgtcgaa accttacatg atcatcgaca tttttgttca cgctaaaaag 3573421 cggaggtgta aatatggatc aatttgaagc agcatatgaa tcgtataaag cccggcaaac 3573481 aactgccgat caagaaaatg ttccatctgg aaaagaagaa attattgcgg ttagaagaaa 3573541 tgaggaagac aatattatcg cagtgaaaac caatacagga agagagctcg actaccctac 3573601 tgcgctgtca gaagcaaaat caggaaaact cgctcatgtt gatgtcttcc ataaatacgg 3573661 gcgtgacatt ttgcgaagtg aaccggacgg catcaaggaa aataacctgt ctgagctgcc 3573721 ggatttttaa acaaatacag ccctgccgta tgttggacag ggctgtattt taaacaaaag 3573781 gctgctggat gtattcggct aaccgttttg cactgtgaga aatatcctct gcagctgcat 3573841 aattcacgcc atagaacaca tatggaggca gatacttcat gccgatcaga ttactcgtgg 3573901 cctgaaatgg tttcaatagc tcactgatcg agtaatgatt tgctccgccc gcttgatatt 3573961 tttccgcttc gctccctgtt gatacagcca gcatcagctc cttgccatgc aaggcatttc 3574021 cttctgaacc aaaagcccag ccataagtca gcacaagatc ctgccatttt ttcaagagcg 3574081 gcggagagct gtaccaatat agcgggaatt gaaagacaat ccgatcgtat tcctcgcaca 3574141 gctgctgttc cttcgcaaca tctatcgctt catccgggta ttccttataa agatcccgta 3574201 ctgtgatatt gtcatgttta ctcaattcct cagcccacgc cttattaaca actgaggtct 3574261 ccatatgagg atgcactgcc aaaaccaata ttttcatcag accacacctt tactgttttg 3574321 atgttatttt atctaaaatc aggaaaagag ccaaataaaa agaaagccct gctaaaaggg 3574381 gctttctttt tttcttttat tcagggcttc cttcagttgt ttcgatatct ttcgcaaaat 3574441 cagggttatc cagattcgca ttaaagaaat ccgctgtgtt cggaagtctg agattcatgt 3574501 tcattttttg agaaatcgta accgtgcaat cctcaagcac atagtcaaaa acgtgtccgc 3574561 ctgaattgcg tccttcgtca atgaagtgca ggtgatagcc agaaacggcg attccgtttg 3574621 cataagctgg tgtcaagaaa cctacaatcg ttcctctcac gttgtcgaag ttgaaaatcg 3574681 gctgtgtttt gaccgcttca accattggca cgtaaggttt ttcttgaagt tctactgttc 3574741 ttgtctgcac ctttttaaac aatccgtcaa tgcgaattgc ataaaataag tttctgcttg 3574801 gcagcatgct gttgatctct ttttcaaagt cttcgcgtgt cattttcgca tcaattttgt 3574861 gcgtcatgtc cggtgtaaag aacgtaaatg aacagaacgg tgaacggtct ccattttgga 3574921 ccggtgtcgc ggttccgtct gagcgaagac ggtaaaattc gccgtcaaac ccaatcagct 3574981 ctccgtcaag cttgttaaag gttccgatac cgaagtctcc atatttcgga atctctgaca 3575041 gttcaaaatc tccgtcatat actccgtcta atagagaagt cattgttgat acttgataaa 3575101 tctggctcac aggctgatct ttttgaccac ggctgagcac ttgaatgttg ctttctcgtt 3575161 tcatatttcc cttcactcct tttatttagt gctgttcata aaacagtgtc gtgatgcgca 3575221 gagtgctaga gagctttcgt tttcatgagt tccccgaatt ctttcggaag cttgtcactt 3575281 gctaaattaa tgttatcact gtagtcaacc gggacatcga tgatgacagg accttcagcg 3575341 ttcatgcctt gacgcagaac atctgccagc tggtctggtg attctacgcg caagccagtt 3575401 gctccgaagc tttccgcata tttcacgata tcgatatttc cgaaatcgac cgcagatgta 3575461 cggttatatt ttttcaattg ctggaatgca accatgtcat atgtgctgtc gttccataca 3575521 atgtgtacaa ttggtgcttt tagtcgaact gctgtctcta attccattgc tgagaataag 3575581 aaaccgccgt caccagagac agaaaccact ttttctcccg gtttcaccaa tgaagcgccg 3575641 attgcccaag gaagcgcaac gccgagtgtt tgcataccgt tactgatcat taatgttaac 3575701 ggctcgtagc tgcggaaata acgtgacatc caaatggcgt gcgaaccgat atcgcaagtt 3575761 actgtaacat gatcatcgac tgcattacgc aactctttaa cgatttcaag agggtgcgct 3575821 ctgtctgatt tccaatctgc aggcacctgc tcaccttcat gcatatattg ttttaaatca 3575881 gaaaggattt tctgctcacg ctctgcaaat tccactttca cagcatcgtg ttcgatatga 3575941 ttgatcgtgg acggaatgtc accgatcaat tcaagatcag gctggtaagc atgatcaatg 3576001 tcagcgataa tctcgtctaa atggataatt gtccggtctc cattgatatt ccagaatttc 3576061 ggatcatatt caatcgggtc atagccgatc gtcagaacaa catctgcctg ctctagcagt 3576121 aaatcgccag gctggttgcg gaacaaaccg atacggccaa aatattgatc ctctaaatct 3576181 ctagaaaggg taccggcagc ttgatatgtt tcaacaaatg gaagctgaac ctttttcaaa 3576241 agcttgcgaa ccgctttaat tgcttccggt cttccgcctt tcatgccgac caaaacgaca 3576301 ggaagttttg ctgtttggat ttttgctatg gccgcactga ttgcatcatc tgctgcagga 3576361 ccgagttttg gcgctgcaac agcacgcacg tttttcgtat ttgtgacttc attcacaaca 3576421 tcttgcggaa agctcacaaa agcggcccca gcctgccctg ctgacgctat cctaaatgca 3576481 tttgtaacag cttccggtat attttttaca tcttgaactt ctacactgta ttttgtaatc 3576541 ggctggaata gcgccgcatt atccaaagat tgatgtgtcc gttttaaacg atctgcacgg 3576601 atcacgtttc cagcaagcgc aacgacaggg tctccttcag tgttcgctgt cagcaggcct 3576661 gttgccaagt tagaggcacc cggtcctgat gtgactaaca cgactcccgg ttttccagtt 3576721 aaacggccga ctgcttgggc catgaatgct gcgttttgtt cgtgccgggc aacgataatt 3576781 tcaggtcctt tatcttgtaa agcgtcaaat accgcatcaa tttttgcacc tggaatgcca 3576841 aatacatgtg tgacaccttg ctccactaag caatcaacaa caagctccgc ccctctgttt 3576901 ttcacaaggg atttttgttc ttttgttgct tttgtcaaca ccctcactcc ttattatgca 3576961 ttttaaacgt aaaattttaa atatcttgtg ataagtttca ctatacactc tttggaaatt 3577021 gacctccaat atcgattcgc cttatgatta atatgtaata cgaattatta acctatggaa 3577081 aggaatgcat attgaatgga gcttcgccat cttcaatact ttatcgcagt agccgaagag 3577141 cttcatttcg gaaaggctgc ccggcggctg aacatgacgc agcctcctct cagccagcag 3577201 atcaaacagc tggaggaaga agtcggagtt acgcttctga aaaggacaaa acgatttgtc 3577261 gagcttaccg cagcaggaga aatcttttta aatcattgcc gcatggcatt gatgcaaatc 3577321 ggacaaggaa ttgaactggc acagcggacg gcccgcggcg agcaaggcct tctcgtaatc 3577381 ggttttgtcg gatcagctac atatgaattt ctgccgccga ttgtccggga atatcgtaaa 3577441 aaattcccat ctgtgaaaat agaactgcgt gaaatatcct cgtctaggca gcaggaggag 3577501 ctactaaagg gcaacattga tattggtata cttcatcctc ccttacagca tacagcttta 3577561 catatcgaaa ccgcccaaag cagcccttgt gttttagctt tgcctaagca acacccattg 3577621 acttctaagg aatcaattac gattgaggat ttaagagatg aaccaattat tactgttgct 3577681 aaagaagcat ggcctactct atacatggat tttattcagt tctgtgaaca agcgggcttc 3577741 agacccaaca ttgtccagga agccacagaa tatcaaatgg tgattggttt agtcagtgcc 3577801 ggaattggta tgacatttgt tccttcctcg gccaaaaaat tatttaattt ggatgttact 3577861 tatcgaaaaa tggaccaaat acagcttaat gcagaatggg ttatcgctta ccgcaaagac 3577921 aatcataatc cgcttataaa gcattttatt catatttcaa attgtcagca gacaagaact 3577981 aaagagagtg atgcaggtac atgaacaata cttgcaatct cttttttctt ttgggattct 3578041 tatggaattt ttattaattt aatataatcg cttagtacaa ctttatatca gtatacgtat 3578101 acatacagta caaatagttg gcaaggacat cagtaagcgc aggacattag tttgatttta 3578161 aaaatgaaag atagagaggt gaagtaaatt attgagttca ccggcatatt cacattgctc 3578221 gcttttttcg taacaatgat ttttattttc tggagaccaa aaggactaaa tgaagctatc 3578281 cccgccacat ttggcgcttt aatggtttta ttgtgcggaa gtgtgtcatt ggcagactta 3578341 ggggaaatcg gaacaaaagt cacgggtgca tcggttacaa tccttgccac tatgattatg 3578401 gccattgcac tagaaagctt tggtttcttt tattgggtgg ctgcaaaact gctccaacaa 3578461 tccaagggtt caggcatcaa gcttttttgg ctaaccaatt tgctctgctt tctcatgacc 3578521 attttcctta ataatgatgg gagcattttg atcacaactc caatcctttt gcttgtacta 3578581 aaatatttag gtttaaaaaa acatcaaaaa gccccatatt tattaagcgg tgttttaata 3578641 gccacagcct ctagcgcacc gattggcgta agtaatattg ttaatttaat ttctctcaaa 3578701 atcattggaa tggatctata tcttcacacc gccatgatgt ttgtccctag tatgatggga 3578761 ctcattttta tgacttgtct actgtttatg ttcttttata aacgtcttcc caaaagcctg 3578821 ccagatatac cgggccattt tcagtctctg cggcatagaa ggtaccatcc tcttcattcg 3578881 ccatcagctc ctttaccaga acgaaatcaa acaaaaatca tgttgtttgt gcttgcattt 3578941 gtttttctcg tcagaatgag tctatttgca gcatcatata ccggtatttc tgttcctcta 3579001 gtcgctgtca tcggatcttt tatcctgttg agctggagat ggatttattt caaaacctcc 3579061 ccaagagact tgttatataa atcgccttgg cacattttta tattcgcttt tactatgtat 3579121 gtcttaattt atggtctgca taatattgga ttcacagagt tacttgtgag ttattttgaa 3579181 cctgtggttt ctggaagcct cgcccatgca actttcgcat caggtatctc tacttcagtt 3579241 ttttctaatc tctttaacaa ccatccagcg ttaatgatca gtacttttac cttaactgaa 3579301 atgaccctga atccttcaac aacaaaaatc atctacttgg caaatattat cggcagtgat 3579361 atcggttcat tattattacc tatgggaacc ttagcaacgc ttatttggat gcatatatta 3579421 aaacagcatg atgaaagtat ttcatggggc gaatatataa aaacgaccat tatcatcatt 3579481 ccgctgactg ttctttttac gttaacatgt ttatattttt ggatcagttg gttatttctt 3579541 tagcacagta tgaaacgaaa aactgccttc tgcttttcaa gagggcagtt ttgtatacac 3579601 tagggaagat gcattgtctt tagatgattt aacttccaaa tgactggctc tccacttgcg 3579661 ttaataagct caatgatatt attagagaca ccctttaata gtccgacttt ttctggcacc 3579721 tctcccatat caaatatgac caattcacca atattttttt tgatctgctc ctcaaaatta 3579781 cgcacaagag gaactttgga aggcacgacc ggcaattgtg agttgtcaag agtatacggt 3579841 gtttgttcag ttgaataagg ggtaaaccat tttaaatgat gcatagatat aaaaagtatt 3579901 ttaaatacgg gtgagaaaaa tacaatataa tcgtttaaaa catttgtaac atatccatgg 3579961 atcgatcgac ccccagttac ataaacttca ataaactggc ctttgacctt gtttaatgta 3580021 tttctatatg aaaaagcttg agtttctgcc tctatcattg gatcttccgg attgatcaaa 3580081 aatggcttct cagtactggt cactattttc gccttgttta tttgatgaag atgcaacaag 3580141 ggaatataaa gataattgca gccatcaaaa ataacaaaaa tatcctgtcc gatatctatg 3580201 agggtgccga caaaccttgt atctcctgaa atgacaacct caacatctgt gttaaggaat 3580261 tgattcaaac ctttcacgat tctcctcctt taactgaaaa agggcatcac tttatctgat 3580321 gctcctccat tatctattaa aatttacgtt tccagtgata gtctatcgtt ctgacaatcg 3580381 tttcatagct ataatcttcc ttttgttttc ctgaactttt tattgaactt gaatagcctg 3580441 gtgatcttga tgattgataa tctgaagatc ttggtgatcg tttagatgat tttgatgatt 3580501 gataatctga agattttaat gatcgtttag atgattttga agaacttttt gaacgtgacg 3580561 aacggccaga tttggatgat tgataatccg aagattttag tgatcgttta gatgattttg 3580621 aagaactttt tgaacgtgac gaacgaccag atttggatga ttgatcatct gaagatttta 3580681 gtgatcgttt agatgatttt gatgagctat atgattttga agaaatgaac gaattgctgt 3580741 ccttatcatt attgtcttcc tggttttgtt catttttttg atcctctttt ttgtacgacc 3580801 cttttggacc taagctgatg ctttttatgt gaaaaggata gatgcgaagc acctcttgat 3580861 ttttcactat agtataatgg ccgtcggcat tatctacaag gataccctca atggcttccg 3580921 gacctccacg attaattgaa acccatttat gagtcagact cttaaaaacc tcgcttaaat 3580981 catcagcttc caaaactcca actggcgtct gctcttctat tttcaaatca ggctcgtgtt 3581041 tacttatact tttgatgtga tggatattaa aatacactac cccatcctca tttgtgttta 3581101 acgcagcgta atcatctccc agccagacca atcttccttt tttagattcc ggaccccctt 3581161 ggttaaattg aactgattgg tttattaaat gtccgattaa gctatgaaaa tcatcagcat 3581221 cgagcatttc ctcagtctca attgttgtgg tgctattatt ggtatcctca gtaatacttt 3581281 tcacatgctc caactgataa taaattattt ttttttcagc ttgtaaagct atataatctg 3581341 attttacagc tgttaatttt ccttttttag attccggacc tccacgatat acagtaacaa 3581401 ttttatcttt cattgagtgc aaaaagttat aatacgatat ttcattattt gaatgatatt 3581461 tcattctcct cttgctcatt caaattcctc ctagtcactt atacatagat gataaacata 3581521 ctgcatatat acgtgtcaca tttatttgtt gaactaattc aatagcctaa ttgtcgcttt 3581581 ttccgcgaat acccattttc acgcattcat aaaatactta aatgatcttt gaggtattgt 3581641 gaacggtttt taatatactc gcagatcaca tccggctcac ggtcaaaacg ctcaatatca 3581701 ttctttttat acgggtccat gaggacaaac ggcctaatcc gttcatacat cgccatgatt 3581761 ttcggttcca tatattctat tgtaaaaaga gattggagcg ttttttctaa caggcgcttg 3581821 taggacttgc gaaactcgga ttcatccaat atccgggcgg ttagtgtatt aaatccttga 3581881 attcttacat aatcggcagc catccgctct ccatggatat ccctgcccca agtcgcatca 3581941 taatcccaag gaatcacctc aaataatccg gtttccccgc ttctgtataa tgcgtagttg 3582001 tggacaaacc cgtcatagtt cgaggtgaat acaataccag caagccagcg caaatactta 3582061 tcgacatcca cgtgttttgt cacttctgac ttaaactgag ctttagggac cgtattaatt 3582121 ttaaaaatca tatcttgtaa ataaaaatca tcttcctcag tccctgtttt cttttcatat 3582181 ccaagctcca gcgatgtttt cgtttccctt tctaaatcgc tcatcagaga aaagttggca 3582241 tcatcatcca ccgcataaaa aatcgcgcca tcagccagct tccttttcgc caaataatat 3582301 tcatctacgg attcaagttc aagataaacc ccttcattct tcccattcat ctttacaaac 3582361 gcaaactctg cctttggaga cagtgtccct agctccgaga aaaaatccag agacaatttg 3582421 tttctcatca aggaagggtc tttatactcc gcatttaagt gaatctctcg cgcgccgcgg 3582481 aatgttttcg gctgataaaa ggaaatatgg tatgacttct ttttgaagtc tctgatatgt 3582541 gatccccgat aagcgatatc aatatccagc cttttttgat ttaccttcat cacagctggc 3582601 accggatcat cgtcccatat atcctttttt aattcacgca agtcttttgg atgaacaaac 3582661 agctgataaa gcggtaaatt ggattgattc ttcatccata atcctcctta caaattttag 3582721 gcttttattt ttataagatc tcagcggaac acttatacac tttttaaaac cgcgcgtact 3582781 atgagggtag taaggatctt catccttaac atatttttaa aaggaggatt tcaaattggg 3582841 ccactattcc cattctgaca tcgaagaagc ggtgaaatcc gcaaaaaaag aaggtttaaa 3582901 ggattattta taccaagagc ctcatggaaa aaaacgcagt cataaaaagt cgcaccgcac 3582961 tcacaaaaaa tctcgcagcc ataaaaaatc atactgctct cacaaaaaat ctcgcagtca 3583021 caaaaaatca ttctgttctc acaaaaaatc tcgcagccac aaaaaatcat actgctctca 3583081 caagaaatct cgcagccaca aaaaatcgta ccgttctcac aaaaaatctc gcagctataa 3583141 aaaatcttac cgttcttaca aaaaatctcg tagctataaa aaatcttgcc gttcttacaa 3583201 aaaatctcgc agctacaaaa agtcttactg ttctcacaag aaaaaatctc gcagctataa 3583261 gaagtcatgc cgcacacaca aaaaatctta tcgttcccat aagaaatact acaaaaaacc 3583321 gcaccaccac tgcgacgact acaaaagaca cgatgattat gacagcaaaa aagaatactg 3583381 gaaagacggc aattgctggg tagtcaaaaa gaaatacaaa taatctaagt tttcattgtt 3583441 tcaataggct gccggcggag gtacggaagc ctattttttt atttgccctg tattagatat 3583501 atgtcatgac ataacatatg caacccgcat catttggttt cctttaaacc atttcgttat 3583561 aatcaaggta tcctaacgat aaaggcggtt gttgctatgt acatatttca agctgatcag 3583621 cttagtgcca aagacacata caagctattg tcaggtaccg ttattccccg ccccattgca 3583681 tttgtgacaa cactttcttc aggaggagcg gtaaatgccg cgcctttcag tttttataac 3583741 gtcgtcagct cagatcctcc gcttctcagt atttctgtta acaggacgga aggacgccaa 3583801 aaagatacag cacgaaacgc agtggagaac ggagaatttg tcgttcatgt cagtgatgaa 3583861 gccatcattg aagatatcaa tgaaacagct gcaagcttaa ggccggatga aagcgagctt 3583921 acacgcacct cgcttcatcc tgttgaaagc aaagctgttt cagttcccgg cattaaggaa 3583981 gcccgcgttc gctttgagtg caaattagag cggcatatta cctttgacaa tgatcaaggc 3584041 atcactacag cagatctgct catcggaaga gttgtctgct tccacctaga tgaaaaggtg 3584101 tatgatgcag aaaagggata tattttaacg gatgaattaa agcctgcctc acgattggcg 3584161 ggaaatcact atgccaagct gggggaagaa ttcacactga ttcgtcccag ctgaagagaa 3584221 ggactattta aatagaagaa actagtcaaa aagaccttat gattacaaaa tatcgcctgt 3584281 aaataactga aaaaatatca aaaaaaagaa cacccagagc aagctcgggg tgttctttta 3584341 tgaaacgttt ttcctttttc ttcgtataaa ggtagattag gaggaattgg aatgacaaac 3584401 ttttggattt taatgctgat cgctattacc atcagtctcg cctctcaatt ttttataaag 3584461 aaaaaatacg gtattgataa atccggctgg cgatataagc atgtcagcaa tacacacaaa 3584521 tggatcgaaa tcactttact tattttgttt gtgttttcac tctccttttt tccagttgaa 3584581 tatttgcttc ttttattttt tattgtgatt gactcaatac gtatttttat ggagtggcat 3584641 tatagacctg aagataaaca gtatatgtac cacattgtag aggtctccct tatgtttatg 3584701 cttttgattt atgtttgtac cctatagtta tttaaatccc cacagccgct ccgtctcccc 3584761 gaggatcggc tccgccttgg agaaagcctt cttcatcaac tttgattgca gccgcttgtc 3584821 ccatcagcgg atcatagtca ccgacaacct ccacgagatg cccgctgtct ttcagttttt 3584881 ggattgtttt gtctgtgaat ctgccctcga ctctgagacc ttcgtattcc tctccccacg 3584941 ttctgcccca tacccagcgc ggttcgctga ttgcctgctg tggatgcatt ccgtagtcca 3585001 gcattcgggt aatgatggcc gtctgggtct gcggctggcc ttcgccgcct tgtgtgccgt 3585061 acagaatttt tggctttccg cctttacaga ccatagccgg catcaacgta tggaaggtgc 3585121 gctttctcgg ttcaagcgtg ttgacatgat tttcatccag tgagaaaaac gatccgcggt 3585181 tttgcagtaa tatgcctgta tcaccggcag tgactgccga gccaaattca aagtacaggc 3585241 tttgaatgaa tgacactgcg ttgccatccg catcgattac ggccgcatat gccgtatcac 3585301 ttcccaccgg cctgctttct gccggtattg cgagatagcc gatttcttct gccaattgtt 3585361 ttgcataacg tttgtccaaa agcctttcaa gcggaatgtc tgcaaacgcc ggatcagtca 3585421 ggacggcatc ccgatctaga aaactctttt tcaatgcctc cacaagcacg tgataatact 3585481 caaatgaacc gtgttcgatt tgggtgaaat catagttttc caaaatgttc agtgttaata 3585541 aaccggtaaa tccctgagaa ttcggcggcg cctgatacac actgtatcct cgataatcac 3585601 ttgatacagg cgctgcccac tcaccccgat gcgctttaaa atcatcgatt gtcatgtaac 3585661 tgccgttatt ctgtaaatgt gagacaatcc gctgagcgag atctccttca taaaatgcgc 3585721 ttcttccttt ttcagcaatc aagttcagac tgtctgcaag ctctttttgc acaaaccgct 3585781 ctcccgggac aggtgctttg ccccttctcg tgaagatgtc agccgtgtaa ggcgtggaag 3585841 ccagcagttc aatattcttt tctgtgtgac gacactgatc agctgataca ggaaacccat 3585901 tttgggcata atcgcgtgcg ggctccaata catctgcaag agacagacgc ccgtactcct 3585961 tcaggaccgc atcccagcta tcaaccattc ccggcacggt aatagcactg tcaattcccc 3586021 gcagcggaat cgcgcttttt cccttatata catctctcgt tacgtttttt cctgaacggc 3586081 cgctgccatt gtagactttt actgcctttg tttcctggtg aaaggtcagc caaaaggaat 3586141 ccccgccaag tccggtcata tgcgggtaca caaccgcaag acaagcactc accgcaacag 3586201 cggcgtcaaa cgcgttgcct cccttatcca gtatgcggtt tccggcttga gaagcgagat 3586261 aatgcggact gacgaccatt tgctttgtac cgatgacaga tttgttcatc acaagtcccc 3586321 ttttttaaga aattttcttc agtataggga gcctgatttt tcacatctac tgatccggca 3586381 gaaaaactga cgaactttct tcttttcgca aataataaga tattttcgca ttcatttcga 3586441 aaacaaatga aaaattatta tttctatacg taacttttat gataaaatga ttgctaaaag 3586501 gctacgaaag caggtggagc aattgagtca tgaatatcaa atccccaacc ttgtacttga 3586561 tgagactgat aaacaaattc tcacgatttt gcatgaagaa ggcagaattt cttatacgga 3586621 tcttggcaaa agagtcgatt tgtcacgggt cgccgttcag gcccgtatca accaattaat 3586681 tgaagccggt gttattgaaa aattcaccgc tgtcatcaat cccgctaaaa tcggcatcca 3586741 tgtttccgtg tttttcaatg tcgaggtaga accgcaattt ttagaagagg tcgctcttaa 3586801 gcttgaggaa gagcctgcgg tcaccagcct ttatcacatg acaggcccga gcaagctgca 3586861 tatgcatggg atctttacca acgatcaaga aatggaagaa ttcttaacaa aacggctgta 3586921 tccattgcga ggcgtcgtca gtgttgattg ccagatgctg atcaaacgat acaaaagccg 3586981 tatgggaatg aagctgtaaa ggagagaaac aaatgaaaaa ccatccttat cgggatatga 3587041 cggccgcaat ggttcgcacc ggcatattag ggttcggcgg cggaccttcc gtgattccgc 3587101 tgatccgcca tgaagcggtc aataaatata aatggattga cgatgatgaa ttcggagaaa 3587161 tattagcaat cgctaatgcg cttcccggac cgattgccac caaaatggct gcttatctgg 3587221 gctttaagct aaaaggcaca ttaggtgcaa ttgtggcgat cctcgcccac attctgccta 3587281 catgtcttgc gatggtgggc ttgtttgcgg ctgtaaatgt gttaagccat tcagcaattg 3587341 ttgcaggtat gattggtgcc gtcacgccgg taattgcggt catgctcgga atcatggcgt 3587401 acgagtttgg ccaaaaagcg cttaaaggtt tcggctgggt taccggcatc ctgtttttta 3587461 tcatcgcttt tatcggcctg caaactttac agattaatcc cggcctggtc attatcattt 3587521 tcttagctta cggggcgttt cattttaaac tgaaagacaa aatcacaaat aaacattcaa 3587581 aagataaagg aatgtcagcc tcatgatatc gatctattta tttatggcgt tttttatcgc 3587641 aaacctactg ggatatggcg gcggacctgc gtctatcccg ctaatgtttg aagaagtcgt 3587701 aaacagatac agctggctct caaacgatca attctcaaat atgctcgcac ttgcgaacgc 3587761 attgccgggc ccgatcgcca cgaaaatcgc tgcgtatgtc ggctacagcg caggcgggtg 3587821 gcccggcttc ctaattgccc tgatcgcaac cgtcgtaccg tcggcgctcg cattgatcgt 3587881 cctgctgcgc atcatccagc gcttccgcca atcacctgtc atcaaaggca tgacgctgtc 3587941 cgtccagcct gtcatcgcgg tcatgatgct cattcttacc tggcaaatcg gcgcagacgg 3588001 catcaaagcg atcggctggg tccaatcgat cgtgattacg ggaatttcgc tccttgccat 3588061 gacaaaattc aaaatgcatc cggcattttt gattattgcg gcgtttttat atgggggcct 3588121 tgtgatccct tatttataga aaaaagcacc tggacaggtg cttttttatt ttagcccaga 3588181 aatgccgttt gatatgacag ctgtttcttc tcctgcgtca ctcttgatca tgtgcttgac 3588241 ttgcagcgtg gttcctgcca ttctcacaga ttgcttcaac tgggacgaat tggtttcaac 3588301 ttgtatccaa acaggaggct ggaccttcca aaataaatag agtgcaagaa tcagcaagcc 3588361 agcaatgacc gacagcaaaa acttcatatc gcatcgcttc ttttcagtaa gcggctcgca 3588421 gcggacagcg cctgatgatc acgaagaata tcgcctggac gattgccttc tcccagcaca 3588481 tagcctttaa aggacattcc cataaaatga aaaatatgtt cgaattgctg aatcagcggc 3588541 agccctttta tttttggatt gtctccgccc actgctatta catatgcctg tttcactgac 3588601 atttgctgtt taaaatcagg aaatctcgga tctctcaacg tctgtgacca gcgatcaata 3588661 aacagcttta atgtccctga catgccaaac caataaattg gggtggcgaa tataagaata 3588721 tggcactgca atatccgttc aatgatagaa tcgtagtcat cttgaacagg acgaaagccg 3588781 ccttgggcgt gacgcagatc ttcaattggt tgaattggat atttctgcaa ataaatgtgc 3588841 tccgcatcga atccttgaac agccttctcc gcaagaacat ccgtatttcc gccagaccga 3588901 gttccgccgt taataaccgc aattttcatg atgcatctgc tcctttgttt acgaatgatt 3588961 ttcttcatca tataatggat tcatcaatca atacagatga ttatttcgat taatccaatc 3589021 gctaaaaccg atttagaaag gaagagaaca agtggaattg aagcagctga tcacctttat 3589081 tacggcggct gaacatgtaa acttcaccct aaccgccaaa atgcttaatt atgcacaatc 3589141 aagcgttacc tctcagatca aatcacttga agaagaaatc ggaacgcctt tatttgaacg 3589201 gctcggcaag cggcttatct tgacagaagc aggaaaaacg ttcaaatctt atgcacagaa 3589261 gatcattgcg ttaacagaag aagcgaaaat ggccacaaat caagtaagag aaacaaccgg 3589321 aaccttaaaa atcggggcga cggaaagcca gtgcacatac cgcctgcccc ctatcataaa 3589381 agaatttaaa caggcttttc cccaagtaaa gctcatattc aaaccatata tctccaatga 3589441 acaagcgaaa gaacagctct tacagggcca gcttgatatc accttcatct tggatgtaaa 3589501 ccggatggaa gacgcactgc acgttgaatc tttgattcag gatgagatca aaatggtggc 3589561 tgctaatgac catccttttc ctgcggattt accagtaaca ttgaaggatc ttcaaaacga 3589621 aactcttctg ctgacagagg acggctgctc gtaccgcacg ctctttgaga acaatttgca 3589681 tgactccggt atctatccta acaaattgga attcgtcagc atagaagcca tcaaacaatg 3589741 cgtgatggcc ggacttggga ttggaatctt gcctgaaatg acagtaaaag atgatattgc 3589801 agcaggccgg atgaaagaac tcaattggca gagcgattgc cccgttttca ctcaattagc 3589861 atggcataag gacaagtgga tgtctgcgcc attaaaggct tttatcgatt tgacacggaa 3589921 aacattcaaa taaaacctct ccacaaggac gacaaggttt ttgagaccag ggcacacaca 3589981 tacaaaaaaa acacttgatg acttagagcc ccaagtgtta cacgtgattt ttctgataaa 3590041 acgttcgcaa aacatgcgtc tcaaggtcag ccaggcggac agggatcggc agcctgcttt 3590101 cttgattgat caagctcatc gtgatctgat agctgctgtc taaatcaata taattaccgc 3590161 aagacaagaa aataggcttc acgtcccgcc gcgttcgcag cgcccgtcca tatacctcgc 3590221 cgtcaatgat aatatcggtg tatgcgccta cttcaatttc aggcgtcacg aaatcgcagc 3590281 ctttgatttt gagataggtt ttcgctatcc caatcgtcgg cttgcccaga aaaaaagccg 3590341 catgggtggc aacgcccata tgattgtaat gcagatatcc gttgccatca aacaagaaga 3590401 catccggctc cgtctccagc tttttcgccg cctcgatgat caagggcagc tcgcgaaacg 3590461 caagaaaacc ggaaacatac ggcacgctga ttctccccat gctgtgcact ttttcaatga 3590521 cttcttttgt atcagcgtca attacgataa tacagcacac tccgtatggt tctccatcct 3590581 gctcccaata ggccaggtcg acgcctgcgc aggtgttgat ggagtctgga tggatcgtgg 3590641 gggataggtt gatacgattt ttaaggttaa attgcacttg taaaaagtct tgttcctttt 3590701 tcatatcaaa tttatgcaca tcaaatacct tcataacgat tgctcactct cgacctaaat 3590761 taatgtgagt ctctcttctc gattctagta tttcaaaatg aggactatct gtatctatct 3590821 cgtacttatt taatagattg ccttcttcat cccaattctt ttcagaaatt agtatggaat 3590881 gctcatactg ttgctcactt tttttcctgc cattttcaaa ccaaattatg cttataccgt 3590941 gcaattgccc atatcggtat tctttttcac tttttttatt cccgttttca taaaattcac 3591001 atgttaaacc atgggccaga ccattcttat atttagtaaa atagatgatt tgaccatttg 3591061 gatataattc gtaagccagc cctgtaaacg gctggccatt ttcgtcttca ggattatcta 3591121 aaatctcatc acttaccgaa gagaaccata aatcctcaaa gtccactccc ttttctttta 3591181 tactcttcat atcatattca ttttccatac tttaaagcct ccggtatata atttgtattt 3591241 tgagttatat attcacaatg tggacatcta ggcattggga caccttctgg catcttttta 3591301 tttattttcc tagcacttac tacatatacc attaaatctt ttaaatccgc atcaggtctt 3591361 tgaagtaacg cttcatttag agcattaact tcggcatgag aacccgcccc tgacgtcttt 3591421 atataacctt ctttaagttc tgtaggcata tttacaattc tatcatgaat aagtggatgt 3591481 agtaccttag gtggcttccc atctatattg tttattccaa aataataatt gcctgttttt 3591541 ttgtccaata caccagctac cgcagggcct ctttgttttt tagttagacc agaagattta 3591601 attctactaa gttcgtttag tacttctgcc cttagattta ttcgatggtg aagatcttct 3591661 ttagacaata caccatgctt atttcttaaa tattgaagcc tagtttgttt ttcttcagta 3591721 gtcttagcaa tattgctaat aaggctttca ttactcactt tattgacata tggagcattt 3591781 ttttggtaca accgatcaaa gtagtgtgcc aatcctgctc caccaataat agtaatagct 3591841 tccagcgccc cttgcttccg cttctcctca gacactttgt ttccgaacat atcccggcct 3591901 gtgacagctt ctgagaatcc gtttgacgca acaaggccgt atgcgcccat ttctgtcatt 3591961 ttgagaatgt ctaaggattt gcctgttttg taggcgtcta atgcgtgttc agcagcgata 3592021 gctgcttttc cggttttgta gatggctttt ccgcctttga aggcccggcc tgcccagccg 3592081 acgactggta tgaatccggc agcggccata gctcctgctg tcacacgctc cgcggtggag 3592141 agtttttctc cggtaaccgg atcaacgcct tcggttgctc ttttataatc ataatagcca 3592201 gtgacttctc cagtaaagtt gcaaactcca tcccatgttt tttcgtacca cggtttgttt 3592261 gcttcttcct cggctttttc ctggagccgt cttgcttctg cttgctgggt ttttgcatcg 3592321 atataggttg ttccttgatt ttctacttca atgacgcttt tgtagacttc attgctgtgg 3592381 aaggcttttt tgtcatagta cataggggat gcgctcttcc cattgctggt ggcctgcatg 3592441 agaacagaat atttggtgag cactgcgttg tccagagatt ctaaattttg atattcagtg 3592501 gtcagggatt catcaagctt atcgacagct gtgattgtat cacgtctgat tttttgggca 3592561 tcgcccatct tatctgcata gtcgtcaagc gtgtacatgt cgagatcaat aatatcgctg 3592621 atgcctgaca aaatagaatc gatttcttct ttatgagcgg agacaatctc tgaggctttc 3592681 aggtctccat tgggcagctc atgatccaaa aaagaagttt ccacatatga atcattcagt 3592741 tcttgatctt taatatctcc tgaaatgccg tttaaaaacg caatttgagc agagacaagc 3592801 gtcagccagc tgtctacgat ttctgcctgt ccctgaaaaa aatctttaat attgtccgcg 3592861 ccatttcctt taaaattatc gcctaaatcg gcaactccct gaaacgcttt tttcagcgta 3592921 ttcagctgct cttcaagcgt ctcatattgc ttttttctgc tcttcgcttc ttcgattaaa 3592981 gattttgatt caaatacttt actcatcgca ctgccctttc tgttctattt taccgctatc 3593041 gcctcgtcct gctctttgag tgaatctacg ttatcctttg tatcctcgat atttttctgt 3593101 accgcttttt tgtaatctcc gagcatggtt ttgatgttct cctcacgctc atggtatttt 3593161 ttcgtataat cgaggctgtt ttttccgttg gatcctgcgg cgccgattga tacgtcagca 3593221 agcgcatctt tgacagaatc taatgttttg atgactgtgt cgtacttcag cttaatttct 3593281 gacataaaaa aagatcacca ccattttagt ttactaattg tatttccgac ttcttccgcg 3593341 aactcttctc cctttttaag aagatctgct gcaccatttg ctatgaacaa ttccgatgca 3593401 tatttagctt tatcccattc aagatcaaaa attttcccgt taatcgaagc catatactcg 3593461 ttatatttat cattcacaat cttagatgct tccgatttcg cctcttctct tcccttgtcg 3593521 aaatcatcgg cttttgttcc cgtccaatgc ttgcccaatt ccggtttcac aatttctttg 3593581 atttcagtga ttgcctcttc ttgcagtgtg tctatgtcct tttttgcttt tttcagcttt 3593641 tcgatcttgt cttccacgtc tgaaattttt ccgttgagcg aacttttgat atccgctagc 3593701 atactttcat aacccatctg aatcacctct taatactcaa aaagtcgtat ggaggggctg 3593761 atgaagatag acttttccat actttatttc catatattat attttaaaat agccagaagg 3593821 cggcttaaat agggtaaatg gcttaattta ggcatataac gctcttgaaa tgtaggtatt 3593881 tgatcttgtt tttgttcgtt atacagctaa taaaagcgtt ttataaaatg aaatcaccta 3593941 atgtcatagt tataaaggca cttgaaagag gcagatgttg ttgatctgcc tctttcggcg 3594001 ctgagcttat tgttcatgtt tatgttcttc atctggtcgg ccatgtctga ttttgtcatt 3594061 tggcttctat tattcccccc ttctgaccct ttggatcaaa agcttgtatt agctgcagtc 3594121 ccagttgtac agaacgtttg aaaagtcttt tttccttaga tcttcaggtg tgatgaaaaa 3594181 attggcgatg ccgacgtctc cccacattga atcgatatca tcgtctgaat caatttgtaa 3594241 cagcatgatg gtgtgttctt tatatgcgta ttcccgggga tcatgctggg taaaagaagc 3594301 gtatccgcca attttatggc caaatccgtt ttcagccagt tcattataaa tgtcttcttc 3594361 atcctcgccg aactgaccaa agaactccat tgtttccatg cccgtatact gctcaaattg 3594421 aaaatctgta ggcagcaccc attccgaaga tttcacaggc tcgactgccg cttctgataa 3594481 aatcggaaaa tcacattcgc ctgtgccaat aaatgaaaaa tcagaaacaa gctcgtcatc 3594541 gttttctacg atattttcaa aatagatcac tctgaaattc ttttgttcac atcgatcgtc 3594601 aaaattcaat ccatagacgt catcatgaac agaaatgtag aactgcagga tacctgaaga 3594661 agggtagccg tcaagctggg gaatgtgcga gaaattaatc tgcgccagaa gtttcatcgg 3594721 ctgtccattt tcgtcagtcg gatatgtttc atgcttgggg aaatagggat caccggcaat 3594781 tttgctgtca tatcgtcctg ttttcccctt tctcacattc agtttcacgt attctttcgc 3594841 tgatttctcc agcaagtcgc ggtacggtct cattttttcg ggcagatgat tcatcagatt 3594901 ctctcctttt ccggcatctc caaggtttta ttttctggtt ttcttctaat gtttttcaaa 3594961 cgaatgttta aagaagccct acttctgcat aattttccaa acaatagtta aatagtagca 3595021 aatgtattca gcaccccgca atagatgaaa aaaagactgg tgcgcaacca gcctttcttt 3595081 ttcatctatt gaattgcacc tgacggaaca accgccttcc gtccgacaga ataatactcc 3595141 actcctgcag ccaaagcctc atccaatgtg tagcagtttc tgccgtcaaa tatgagcggc 3595201 gtttccatca aatcctgata agccgctaac gggaattgtt taatgtcagc ccagtcggtt 3595261 aaaatcatga cggcgtcaga ccctttgaca gcttcctcga tcgtctcttt atattcaaca 3595321 gcttgcggga gaacatgctt tgcatggcta actgcaatgg gatcgtaggc tctgatacgg 3595381 gcgtcgagcg cagcgagacg gtctgcaata acaattgacg gcgcttctct catatcgtcg 3595441 gtattcggtt taaatgacag gcctaaaagg gcaatcgttt ttcccgtcac cccaccgagc 3595501 ctgttcagcg ctttatcaac cagcatcgcc tgctgattgt tgttgacttt gataacggat 3595561 ttcagcagtt caaaatcatg ctcgacattg ccggcaattt gcacgagggc gtttgtgtcc 3595621 tttggaaaac aagagccgcc gtagcctatg cccgctttta aaaactggct cccgatccgc 3595681 ttatcctgtc ccatcccgta tgcgactgct tcaatatcgg cgccgacctt ttcacatata 3595741 ttcgaaattt cgtttataaa actgatctta gtggccagaa aagcatttga ggcatatttg 3595801 atcatctcgg cgcttctgat atccgtttgg taaatcggga tttgaaacgg acggaagagc 3595861 tcctccagcg tatttgctgt tttctcatcg gccgtcccga tcacgatcct gtcaccatga 3595921 aaggtatcat agatcgccga cccctcacgc aaaaattccg gattggatgc gaccgaaata 3595981 ctgacaggct ccgctagatg ttcagtaatc agtccattaa tcaaatcgtt tgtcccaacg 3596041 ggcactgtgc ttttcgttac cacgactgta tctcgtttga catgctttgc gatgcgtttg 3596101 gccgcatctg taatttgctc cagattggcg tgcccgtcgc ttttctgcgg tgtgccgacc 3596161 gctataaaaa tgatgtctgc ctgtgccaag cctttctcat agctcgtttc aaagttcagc 3596221 cgtccatcag ctgtattttt tctcatcagc tcttcaagac ctggttcaaa tatgggggaa 3596281 atgccctttc tcatttcatc aatcttgtga gcgtcaatat caatgcaggt tacatgatgt 3596341 ccaatctcag aaagagaaac acctgtcaca agaccgacat agcctgttcc gatgactgtt 3596401 atattcattg tttccctcca acagttaaat tgctgctttg cagcttccgt aatatcgtat 3596461 gagaacatcc tatcatgaat gcgaatgatc tcccgcatag cctgtcgggt acagcctgta 3596521 cagatttctg aaatgtgatt caaccataca atacactatt atatcgctct caaaaagaaa 3596581 gtggtgaaat gagaatcggc tgttaaaaaa aaccaaacaa ttttcttctt ttgaccggct 3596641 gcggaggctg tctgaagatg gtctgattcc gcaggagaag ctctgcattt tccgtcagca 3596701 tataaggaag ttccgagccg aattctttct ctagaacata aagagcctct tgagtgtgaa 3596761 aatttctcgt tttcacatta tgggcatctg aggctacgaa atggatcaaa ttggcttcaa 3596821 ccagccggag agaaaatgct ttcagctgct tgccgaagat ccccgcaaga cttcctgaag 3596881 taatctgaga tgctgctcct ttttccacaa gatgatacag caaggacggg ttttcgcgaa 3596941 tttccctgtt gcgttcagga tgggcgataa ccggaatata tcctttcagc tgcaaatcat 3597001 aaaaaagctg ctccgcatat cggggaacgt gatcaaacgg aaactcaatc aagatgtatt 3597061 ttgtatcatt cagcgaaagc agctgacgtt tggcaaggtc ttgttccacc tcgccgtaga 3597121 ttctgatttc ctgtcccgga agcacatgta aaggaatgtc ttctttgatt aaacgtttgt 3597181 ttaactgatc tgctgcttct ctgactgcgg ctggctcgtt tttatacaca ccgttgttat 3597241 gatgaggtgt cgcaatgatc gtccggattc cctgacgaac agctgctctt gccatttcta 3597301 tgctgtcggc cgaatcacct gccccgtcat ccattgcggg aagaatgtga cagtgaatat 3597361 cgatcatgtc ctagccccct tttttcgcaa aaataaataa cgggcacgat gcacgttatt 3597421 tatttttgca tgaaattgtc cttggttccg taatatccgt attcagagtg cttcgaaagc 3597481 tttttgccgt tcataatcgc cccaaggagc ttgcttttgc acgttgcaag cgcctctttc 3597541 gcttttgcgg cttgttcttt ttctgttttc ccgcttgaaa taaccagaac agaaccgtct 3597601 gccacgttgc ctaaaatctg tgcatctgct acggcaagaa taggcggcgt atcaaaaatg 3597661 accatatcat atgccgcaca cgcttcgtat gcaagctcct tcatccactt cgaggagaga 3597721 agctcggccg ggtttggcgg gatcgggccg ctcgtcagca cgtcaagatg tttttcattc 3597781 gatgcttgta cagcctgctc catagagctt ttctttaata aaacagatgt taagccaacc 3597841 gtattttcaa gaaaaaaagc cgtatgtact gttggttttc gcaaatcagc atcaatcagg 3597901 agcacttttt ttccctgttg ggcgaatacg acagccaggt tggcggccgt tgttgatttt 3597961 ccttcccccg gacaagccga tgtaatcatg actgatttca tttgccggtc cactgaagca 3598021 aattctatat tcgtgcgaat cgtccgatat tgttcagagt tcaaggattt cggctctgtc 3598081 attgcaatga catttctctg catccgcgag cctctgtttt ttctaagcgc caaaatgtcc 3598141 actccccgtt ttttcagatt ggaaaccctg taaggtcttt gctgttttct gctcattcgc 3598201 aatggtggaa actgtcccta aaacaggtat gtccagcaag gattcgagct gctcttccga 3598261 tttgatcgta ttatccaaat gctcaagcag gaaggccagt ccgatgcttc ccgccaatcc 3598321 ggccgcaaac gcgatggcaa tgtttagtag cggctttggc gatacagggg acgggtgttc 3598381 tgaaacctcg gcttttgaca gaatgctgac attgtcaaca ttcataatgg atgtgatttt 3598441 gtcttgaaaa acagatgcta tagtattggc aatatgagcc gctgtttccg cgttttcatc 3598501 cctgactgat atgttgacca cttgggagtc ctgttcgctg gatacggtaa ttttgtcatt 3598561 cagttcttgg gatgtcatcg acaggcccat ttctttaatg acttcatcta agatggcagg 3598621 gctcttaatg atgacattgt acgtattgat taactgaaga ttggtttgga catcgttaaa 3598681 ttggacttct tttcgttcat ttttcgattg gttgaccaga atctgagttg aattttcata 3598741 gatgggtgta agtgcgaaga aactaatgag tccgccggca gcagtggcag ccgcggttac 3598801 aatcataatc aaaagtatgc gttttgttaa cgttgataat atctctttta agcttgtaga 3598861 ttctcccatg atacctccaa atctcttata acatcctttt ccatctacga ttatacaacg 3598921 ttgaaaccgc atttctccag cttttcacgt gacataattc gacatttttt tacaatgcgt 3598981 tatgttagta ctttttatgt aagcgctata tttactgtgt tgacagtgct gtctcatttt 3599041 ctcttattcg ggcagtcacg ttctctcgca taaaaaaatc ccgctaaagg cgtgcgggat 3599101 ttttatgttg catatccatt tttaatatga gaaatcaaat tttcaagcat ttccttcgtc 3599161 gtcatctcag atgactgctc accaatttca tgtgcatgca tcaaaatttt cagaaattct 3599221 tcttgattca atttcttttc actcatcttt tttttccttt cagcttccat taagttgaaa 3599281 acacgattat tatatgatgc tggttatcaa tttgcaatct ctaatacatc attcgacaca 3599341 tcctattttt tatgtccttt tttaggaaaa actttttaag gccgatgtgt tgcgatataa 3599401 tagagaaatt ggatcttttt attacgtgac tcggttagga gcgataatca tgcttcagaa 3599461 tatgatttcc aaagacgatg tgctggcatc tgctgaacag ttaaaagaac ttcttcctta 3599521 caatgaggaa aatgttcagc tgatcaaaaa agcccttatt ttatatcggc aggattcagt 3599581 ctatcgttta caagcagtga gtccgacgga agttacggct tacgtgcagg atgttgtgcc 3599641 tgtgcgggtc acattgaact tgtttgtcat agtcaaaagc ggctgttcat gtccgtccgg 3599701 aagaatctgc cgccatatgc tggctgtgtt tttatatgta tatgcaatgt tcgagcgagt 3599761 gggtactttt acagagtatt ggctggagag ggaaaagctt gaggaaagca aagagctcgt 3599821 ccgccgccag tttcaggaaa aggtgctgcc taatgaagaa tcactttcaa gctggcttgc 3599881 tttttttgat tcagagtttt ctctctggca ggcacgtacg ccagaaggca gccaaaacat 3599941 gcagggcctc tattacggct acctgtccgc attaaaaaaa catgcgccga acaagccgga 3600001 gctgaaaagc ctgtatcaga ttcattccgc gattgcggtt tggcttcgca tgttcacatt 3600061 gattgaagcg ggcaagctaa accccgaaca agatttttat tccctcaatc cgtacgttga 3600121 acagctgatg gatacaatct acagctctat tgataaatta aaaacgtacg cgctgtcttt 3600181 tgcgcttgat ccgtttttgg ataaaacacc ggatgttatc cggcatttgc tgttgaaaga 3600241 agaaattttc caatatgaac gcatccgcgt cttcggtgaa atttggagtg cgctgctgtc 3600301 gcggccaaaa tgggtggcac gcgaacagga gatattgaaa aaagaagcag gacggcgttt 3600361 ttctcccgaa ttgcaattcg ggcgcctgca tttggaattc ctgcaaaaaa atgatgacgt 3600421 tatttttgag gaagcggatc aattcccgcc ggaagcgctc ccttatacat tccaatggct 3600481 gagtgaaatg actgccaaga aggactggaa acggcttaaa acatggtacc agcaaattga 3600541 accaattgcg atgggttata cgaagctgga taagccgttt aaagagattc gcgatgtgat 3600601 cggcgagctg ttccttctgt tgaatgccta tgtgcagcaa accaatgatc aagcgctgtt 3600661 tgagcgcttt gccgcgggct gtctgccgta tacgttcaca gaatacagcc atcatttata 3600721 tgaaaaaaaa cgctatgccg agtggattga aattcatagc cttgtcggct tttccatcaa 3600781 tgaaatggat aaaatgatgc tcaaggaaat tgcagcgagc gaccctgagg cgcttatacc 3600841 ggcttaccat agagaagtgg cttttttcat tgatcagaag aaccgtagct cgtacaagga 3600901 agccgcccgg tatttgaaaa aattgcgcac cctgtacaaa aaagcgaaaa agcagaaggt 3600961 gtgggagcgg tatattcagc tgctgagctc gcattacaag cgcctgcgtg cgcttcaaga 3601021 agaactgcag aaaggaaagt tgattgatgg cgagtcttaa agaaattctc atccacgtcg 3601081 aacaaatgga agatgggtca tttacgctct cagcctttga tgagaatgag cagcctcttc 3601141 cctacagcca tatgaaaaag catttgttcc aatggcatga atcctcattt tacggaacct 3601201 ttctagagga tgtcagcttc atcgggacga ctgctgtcct tctatctcca tggatgactg 3601261 tagagcttct cggcaaaaac tcgttcaact cattcagctc cgtgcagctt acagaagaaa 3601321 cggagccgct gatcgaggcg gcatcgacca tctatgaatt tatcgcggac ggcgatttta 3601381 tgcctgacta tgacgcatgg acaaacggtg tttttcgctg gaaggaccgc gataatatac 3601441 tggaaggctt tactgcggaa tggttttccg ctgccgtaca ggattacatc cagtacgacg 3601501 atgacctgcg ggagaaatgg gaacatatca aggaaaaatc gcctgcggtt acgacattcc 3601561 gtggccattt tcttgatgaa gaggattttc tggaaggcat tggctggatt gacgatcaat 3601621 ctccatttac tgtcggcttg cgcttaaatg aaccggactt tgacggagac gaatggaaga 3601681 tcgagatgtt tttacgcgat aaaaagagcg gtgctgtaga attctttgac ggactgaaga 3601741 gcctcaaaaa atcgtggcag gcgtacagcg ataaaatcgc gcgtgagcag gaccgctttc 3601801 acagaacggt tccgtggctg tcgtttgatt ccgggacaac gctgatctcg gaggaagaag 3601861 cctggatctt cctgtcagaa gcaagtgaga cgcttgtcga tatgggggta gaaatcctcc 3601921 tgccgtcctg gtggcagatt gtcagagaca gcaacatgat gctgaaagca aaggtgtctt 3601981 cctccccgcg cggcgagtca tttgtcggca tgaatgcact gcttgatttc aactggcggt 3602041 ttgcgacaaa tggaattgaa ctgactgagg ctgaatttaa tgagcttgtc gccagcaaca 3602101 ggcgccttgt taatatccgc gggcaatggg ttaaaatcga tccgcagttt atcaaacaga 3602161 tgaaacgcct gatggaaaaa gcagaatcag agggactcca catgtctgat attctggcgc 3602221 gggagctaat ggatcagcag gatggcggac ttgaggattc ggacctgatt gatacatctg 3602281 cttttgccgg cattcagttt gatctgtcta aacagctcag gtcactgatt cgaaagctca 3602341 ctgccgcgga aaacctgccg gagcacaaag tcagtccttc tttcaaagga acgctccgcc 3602401 cttatcagaa atacggcatg aactggctgc tgtttctgcg ggaaagcggt tttggcgcct 3602461 gtctggctga cgatatgggg cttgggaaaa cgattcaaat gatcgcctat ttccttcacg 3602521 tgaaggaaag cggccgacaa aaaacgcctc atttgattat tgcgccgaca tccgtacttg 3602581 gcaactggca gcgggagctt caaacctttg cccctgatct gtctgtcgcg ctccattatg 3602641 ggccgcgccg gccaaagggt gatgatttcg ccgcgcatta tgaaaacgca gacgtggtgc 3602701 tcacttcata cggtctgtca catgccgata ctgaagagct ttcttctgtg acatggaaca 3602761 cgatctgcct tgatgaagcg caaaatatta aaaacgcgca tacgaagcaa tcacgcgcaa 3602821 tcaggaagct gaaggggctt caccatatcg cgctgagcgg cacgccgatg gaaaaccgac 3602881 tgactgagct gtggtctatt tttgacttca tgaataaagg ctacctcggc agtttgaccg 3602941 gcttccataa acgctatgtg ctgccgatcg aaaaagaccg ggacgaaaag agaatcggac 3603001 agcttcagca attaatccgg ccattccttc tccgccggac gaaacgggat gaagaggtcg 3603061 cgcttaatct tcctgagaag ctggaagaaa aagaatttat ccctctgtca gccgagcagg 3603121 catcccttta tgagcagctc gtcaaagaca cttttgacca tatgacatcc ctgaccggca 3603181 tgcagcgaaa agcgctgatc ctcagcatgc ttggacggct caagcaaata tgcgatcatc 3603241 ccgcgcttta tttaaaggaa gagcaaaccg agctgctggc cggcagatca gtcaagctcg 3603301 aaaaattgct ggaactgatg acagcgatcc gcgcccaaaa cgaaagctgc ctgattttca 3603361 cgcaatacat tcagatgggg aacatgatga agcggctgct tgaaaaaacg ttcggggaac 3603421 ctgtgcaatt tttaaatggg agtctctcca agcaagagcg ggatacactc gttgagaaat 3603481 ttcaaaggaa agaatatccg acactgattc tttcactcaa agctggaggc accggactta 3603541 atttgaccgc cgccaatcac gtcatccatt atgacagatg gtggaacccg gcggttgaaa 3603601 atcaagcgac tgaccgtgca taccgcatag gccaggagcg ctttgtccac gttcataaaa 3603661 tgattacgac aggaacaatc gaagaaaaaa ttgatgtcat gcttgaatcc aagcaaaccc 3603721 tgaacgatca aattatccaa agtgaaaact ggattaccga gctttccaca caggagctcg 3603781 aagaattgtt tacattaagc gctacagcgc aataatcatg actaaaaaag ctggctctaa 3603841 aagagccagc ttttttccgt tcatagccgt cacgccgaat ttccaaaaaa tccgttacgc 3603901 cggttatcaa cagggtgcgc ttttgtggca gcacatatac ttacaacaaa tgtttcatca 3603961 tatgtgcgac accgtgttcg tcattggtta aggtgacagc atcggctatc gatttgatgt 3604021 cttcccgggc attgcccatc gctacacctt ttcccgcagc ctccagcatc gatttgtcat 3604081 ttaaactgtc acctacagca gcagtttcct cgagcggaat attcagctgt tttgcaagcc 3604141 tcttcagcgc ctgccccttg gaagctttgc gggaagaaag ctcaaagttg tgctcagccg 3604201 aactgacaag cgtcaaatct tcggcatgct catatctttt ccagcctgcc tcaagctttt 3604261 ctttgaagaa agaaaagccg agaatattgt aaaaatcgat tggctcatcg gcttcaaaca 3604321 gctcttgaaa ggagttaatg taagcaaagc ccgattggct gtattgcacc tcggccgcct 3604381 gcttaaggac agaaagatcc gcttccggat ttgcgcttct gaatctgtcg agctcaacat 3604441 caagaagttc tctgccgttt tgcggcgtat aaatcgctga acctgtgaat acctcataat 3604501 aatagttttc cgactcaagc catgagagaa tgtcatacgc ccgtttctta tcaatcgttt 3604561 cgtgatgata aagcctgccc tcgggatcgt gaatgacggc gccgtttgca ctgatgaccc 3604621 atgttttgat ccccagcggt tcaaagattg acatgacgtc aaaatgagcg cgcccagttg 3604681 acaccaccac ttcaatgccg tcccgctgcg cctgccgcag tgcgttttca ttttccaagc 3604741 ttacctgatg cttgctgttg agtaaggttc catctaagtc aatcgcaatt aatttcacgt 3604801 ttgtcagtcc tttccttcat cctgctctgt cacgagaagc tcaacgccgt ttcggtcaag 3604861 caagtcacaa aatgcctgat tcggcagcct gtctgtaatc aagaggtcga tttcattcag 3604921 ctccgcatac tgataaaaac tggtgctgcc cagcttagaa tggtctgcaa gcgcaattac 3604981 ctgctttgcc tgctgtatca ttttccgctt caccatgcca tcctcttcat gcgcaattgt 3605041 aatgccatgt tcggaaatgc cgaccacacc aatcagcgct ttatcaacat ggtagcttga 3605101 gagcttttca atcacagagg acccgtacag aaagcggtgc tccttttcca gcttgcctcc 3605161 cagcagataa atttcaattc cctctttatc ggacagcaca tccgcaagat taatcgaatt 3605221 ggtgattacg gtacaatcaa ccgcattcaa atgctttgca catgcctgaa cagttgtaga 3605281 ggcgtctaaa atcacccggt ctccatcatg aataagcgat gctgcaagcc tgccgatctt 3605341 atttttttcc tcagacactg ttttcaggcg gccggaatag ctttgaattt tctgatgcac 3605401 agtcggtaaa atggcgccgc ctcttgtgcg gatgatggca ttctgttcct caagtttcac 3605461 aagatctcgt cgcgctgtat cccttgacac ttgcaggagc gtacagatct gctccgttgt 3605521 aattcggtta tgctgtttta aaaaatccaa aatcgctact aatctttctt cttggtacac 3605581 gccctcattc cttttctcag caatcattta taagtaatta taagttttta tttgatttta 3605641 ttcaacatta ataagtgatt ttaagtaaaa atgcgtcgag agaaccaatt tttcctaagt 3605701 aggcaaaaag aaagaaccag tctggtcgac tggtcaattt tgaggggatg atgcgaagat 3605761 ccggataata gtgaatggat agataacggg aggagcaggg gtgtcaatca gcagcttttt 3605821 cccggggttt agggtccata aaacgaacag tgtcagccaa cacttctgtt acatacacgt 3605881 taacgccttc ctcgttttca tagcttcttg tctgaatccg tccgcttacg ccgacgagag 3605941 aacctttttg gcaatacaac gccgtgtttt cagctgtttt tctccaaagt gtgcaattga 3606001 cgtaatcagc ttcgatttca cctgaagcat tcttgaagct gcggttcacc gcgagcgtaa 3606061 catgtgcaac tgccgcaccg gcggaagtgt agcgaagatc aggatctttt gtaagacgtc 3606121 cgacaagcat gacctgattg aacatgcgat tcctcctctc cttgcggttg tatgtattgt 3606181 aaatgatgca acaagaaaag aaaaacgctt aaaaatggct ttcagcctct gtttttatct 3606241 ttcgttttca tttttccttc agctaaaaac atcttttgct tttttccttt gaagaaatat 3606301 gtacttttta aaaaacggaa aaagatttgc tttgtcagcc agttttgcgt attcatgcgc 3606361 acataggaag agccatccca cgcaaaccac tgaaagctca attttttttc cggcattgac 3606421 agcttgattt tatactgctc catgccatct tgtgtttcgt ataaaaaact tattcttcct 3606481 tttttgttca gatgaacctc aaacacttct ttacggctta acatatatgt tacttccttt 3606541 tgaatcaaat gactttcaga aggaacgccg tcaatataaa tttcttttaa acgaaattga 3606601 ttcataccac atctctccgt aatccatagt cagttacagt ataatgaaaa aatagaaatt 3606661 attaaatgtt tcgctcatac aaaattcttt agccccaaca ttgcaggatt ttttcctcga 3606721 aaacgtttat gttataatgg aaggcaagaa aactttggaa gtaatcgggg tgagaagaaa 3606781 tgaaaacctt taaactggtt gacctgaatg tggaacgagt ggacaaggaa gaacaatcaa 3606841 ttgaacagtt tccccttatt gacggactga ttataaataa agaagacggt gaaaatcact 3606901 ggctgattga ggcgcttgta cagaaagaac atctgtcttt ttttgaacag cttcaaaaca 3606961 gccaatctga agccaaagta tttgtaacga tcacgaaaaa aagcaatcgc cccgcccagc 3607021 tgacagcagc agtgaaaaat atcgtcaagc tggaagaaag cattcaggtt ttactctacg 3607081 gacaaatggt cacaagaaaa cagcagggca ctgaaaccat tctcgagtcc cttgtaaaag 3607141 agggctatac aggaacaaaa ctcattgagg catttaagca aaaattataa atatgagggg 3607201 gcatgttccc caaaacagac tcagaaccga agagcatcac aatagacatt tagaatagat 3607261 atgttctgca tgaaaaaagc tgccgttttg aacggcagct tttctcttcg tgctttcact 3607321 cttgcatatt taatttgtat ggccaaaaga atcaaccaat tcccctttca caacgaggcg 3607381 cccttcggtt ttgaccgcct tgtcacatgt gattaacgta atctcctttt tgtttgtctc 3607441 ctcaactaca tctgcatcca tttccgatat gatgtctttc gatgttacag aatagatata 3607501 atccttttta aaatccgtga tgacaatttg ggcacctgtt tttatgtttt ccagaggtcc 3607561 gaacagaaga ttcttttgct tcaaatgatg gcccgccaac ggataatttc cctcacccat 3607621 tttttgatcc cggcgcattg ttgccgcccc tatcaaaaga ttttcattgg ttgtgccttt 3607681 tacgatcgga agctccagat cgacactttt aattgttatc cgccgccttg attgtgaagt 3607741 aaaaataagt atatttcacg tgctttcgac gttctccact tgactggaat gctttaatgg 3607801 cgatcccggc atctgtagct tcaggctttc cttcagagga atcagaaatc tcaaactcta 3607861 ttttctcagt gttcagcaca taaccggctg gcgctttcgt ttcaacaaaa gcgtattgtc 3607921 ccggtgcaag gcctgaagct gtgacttgat gatgccggat atgactggtt tcgaagtctg 3607981 tatgaaaatt cgcgaacgat tcagcatggt tgatcttccg gttctgatca ttacagctgc 3608041 cattatcggc catgacaaat acaaggcttt tcatgccgga gcgaatgaca ttttgcaaaa 3608101 accctatcat tactctgaat ttatggcgcg tattcaaaac ctgataatga tgaaacatac 3608161 agcaaatcaa gccacaagaa tggaaatggc gtttctccag tcgcaaatca agcctcattt 3608221 tctttataat gtattaaaca cgattatttc tctcactcat ttggatattg aaaaggcccg 3608281 ggaggtaaca gaggaattta ccaactattt aagaatgagt tttgactttc aaaatacatc 3608341 agccatcagt tccttcagac atgagctttc gattatcaat tcctatcttt ctatagaaaa 3608401 gacgcgattc agtaatcggc ttgaggttct tttcgatata gatgaagaca ttgactttat 3608461 ccttccgcct ttaatgattc agcccttggt ggaaaatgcc gttcttcacg gtgtcagcaa 3608521 gaaaagaggc ggaggatgga tcaaactgac agctaaaaaa caaagcaaaa atgagtatca 3608581 catcaaagta gaggataacg gtcccgggat aactccggaa aaacaaatag atctcttatc 3608641 aacggatttt gatcgcagcg tcggattgaa aaatatcaat cagcggctga aacatttttg 3608701 cggaagcgag ttgatgatca gcagcactcc ggatgcaggc acctctgtct caatgctcat 3608761 tcatctcgct gaaacaacag gaagccctaa agaactgaag gacacagaac gaacctaaac 3608821 gaaaattgag ataaaaaaag acgccgtttc taacggcatc ttttttattc cggcgacttt 3608881 gcttgctgct tcagcaggtc tctgatttct ttcagcagct cctcctgcgc atccaccgct 3608941 tcctccgcag cctcttcttc tgcttctttt ttgcgcctta acccattcaa agtccgaatg 3609001 acgataaaaa tggagaacga tataattaag aagttcacaa tcgtctgtat aaagctgcca 3609061 tatttcacta cagcatcgcc aaacgtaaac gacaggcctg aaaagtcaag ccctcccagc 3609121 agcaaaccga ccaaaggcat aatgatatca tttactagag atgtgacgat ctttccgaaa 3609181 gcgccgccta tcacaacacc aatcgcaagg tctacgatat tcccccgcat ggcaaaggct 3609241 ttaaattcat tccacataca atcacctgct tttctatatt tgtaaagaaa aaaagacaaa 3609301 tgtgccgctg gccatctgcc ttttttcaat tattctccga gggcaaaagt cagttctact 3609361 tcgcaaacga cttcgccatc aactgtggca acgccttttc cgcgcccgat tgtgccgcgg 3609421 gcacgaatga tttcaacctc aaggtgaagc tggtcaccag gcttgacttg ttttttaaag 3609481 cggcagttat caatgcctgc aaaaaaagcc agtctgccgc ggttttcttc tttaatcaac 3609541 atcgcaacag ctccgacttg agcgagtgct tctacgatta atacgccggg cataaccggg 3609601 tactgaggaa aatgtccgtt aaagaactct tcattagcgg ttacattttt atagcctttt 3609661 gcccgtttgc cctcttcaac ttccgtaatc cgatccacaa gcaaaaacgg ataacggtga 3609721 ggaataattt ctttaatttg ctgagtatca agcattgtct tgacatctcc ttcatctgca 3609781 ttagtatgta tagcaatcat caaagatcca atctgtacat ttgaaaagta tattatgaat 3609841 taatctcttt ttcaaccgcg ctaaaatgta accaactgtc aatgagagcc gtcaaaagtt 3609901 atgatatgat aattatagat tttaccaata gcaaagaggt aggaaaatga tttcgaagtt 3609961 tattgaaaaa agaatgctaa acatgttaga cgagtggtat tccgcaatga gcaaacgcaa 3610021 aatgaatcac gtttgcacac tgaaagagaa aattgatcag caccttccaa agatcaaaaa 3610081 gaacacaaaa ctttggatgc gttatcaatt gtttcaggcc cgccatcagc tgctttttga 3610141 aaaccagaac ggactcgatt cattgttcga tggcctatat ggcctggaag acaaaatgga 3610201 tgatgaattg aaatattatc tgtatttttt ctctgggtta tatgagatgg taaaaacagc 3610261 tccgaaacat gcagtacatc attttaaaaa agctgaacag tacctggccg ccattcacaa 3610321 tacgtttgaa gccgctgatt tatattatca aaccgccggc gcctattact tgatgaaatc 3610381 accgccgctt tccgtccaat acgtcaaaaa agcattacac atctatttgc accaattcgg 3610441 ctatatcaaa aaggtaatca cctgtaaact tttgctcgcc gtgaattata ttgatcaaga 3610501 acgctatgaa aaagctgaac agcttttcaa agaaatcatt aagaaaaccc agcaactaca 3610561 tgacgaaaac ctgctatgcc acgcttatta taaccttggc tttttaaaag cgaccgagaa 3610621 aaaagaccag gaagcgcttc tttactttag aaaagtatta aagaatcaag aatttgaaat 3610681 gaattcacca gtctcatatc ttcattgtgt gtacgagtct gtcagagcgc tttttaaaac 3610741 agggaacatc acagaagcta aagccgtcct tcaaaaagga aaagaattat ctgaaaaggt 3610801 agacattcaa accatttatt taaaattaaa aacgcttgaa gccctctaca catcagccga 3610861 agacccttat gagcagctgc tcgaatatgt gcttgaatta gaaaaaatcg aggcgtgggt 3610921 ggatttagaa gtgctgttag aagatattac ggaatactac aaaaaaaagg acgatttcga 3610981 aaaagccgct ttttttatca tgcgcggctg attgaaaaac gcccattttc ttattatctg 3611041 actgaattga ttaaaccgag catttgatct cccattgtga tcgttctgct gttcagctga 3611101 tatgaacgct gggacgtgat caaatctgtc atttgttctg aaatatcgac attggacatc 3611161 tcaagtgagc cctgctgcat gccgatgttt tgtctattag cgccgttcag ctcttcaaaa 3611221 gctgccgcat tatcaataga gaaaaggtta ttcccttcgg atttcagctc ttgagggtta 3611281 ttcacttgga caacgccaag attaaaccgc tgaaccgcgt ttccgtcaga tgcggttaag 3611341 gtgccgttct tattaatggt gatattcttc attgagctgt cgatgttcac tgtattgccg 3611401 ttctcatcaa gtacgggata cccatttcca gtgacgagct gcagctggtt ggcattcgca 3611461 gcggacggcg ttacatacag cgccccgtcc ctcgtatact ggcggtttcc atttacattt 3611521 acctgaagat actggtatgg agacgtaaat gcgatatcca gatcgcgatc ggtcttctga 3611581 atgcttcctt gatcagagac taggcgtgaa ctcatcatcg ctccgacgcc aaggcgcaag 3611641 ccgggcggcg tttttcgggc ttttgccact tcctcgtttt tttcatcaac ctgatcgaat 3611701 tgctgtctga caagctcaga aaaattcgta tcttttgcct tatagccggt tgtgttgctg 3611761 tttgaaaggt tgctgctgat tgtgtcaatc tgctgctgca gctggtttaa ggttgttgat 3611821 gccgttagca ttgacctgag catagttgat gtcccccgtt tttttcttcc gttttcttaa 3611881 atttttccaa tttcatttgc tgctttatcc atacttttat cgtaagcctg aataaccttc 3611941 tgattcgcct caaacgatct gtacgcttca gtcatttctg tataggcgct tgtcacatcc 3612001 acgtttgaaa gctctgagac gccttgtttt aatgaatagg ctacctgatt atttccggct 3612061 gcgcttggca gatcattacc gtccgccgtg ctgtacaaat catttccgtc ccgtttgaga 3612121 ttgcggacat cttccgccat tctgacatca atctggccgg ctgtgcgtcc gttcgttgtc 3612181 acagtaccgt tttcagacac agtgaaattc tcattatcaa cagtgattgg ctggcgatcc 3612241 gtcgataaaa tagggcgtcc gttgatcgtc agctgattgt tctcatttag tgaaaatgtg 3612301 ctgctttttg aataacggat tccatccgct gtttgaaccg gataaaaaag agcagctttt 3612361 tcattggttt ccgcactcat cggaacttga ttttcgatca atgcaatgtc tgtaggctgg 3612421 tctgtggact tcaggcttcc ctgtgtaaag agaggcttga gctcctgcat atatactccg 3612481 gtattcacgg aaccgatttc cgtccttgat gtcccggccg gagattttga ttctattctg 3612541 ctgagcagca tctcagggaa cgcgcgcata gagccttgat cagctttata tcctgatgta 3612601 tttgcgttag caatattatt tgaaagcatt tccgttcttc gctgctgggc aatcattgcg 3612661 gatgttgctg tatataatcc ttttaacaaa tttcccacct ctaaaaatgg cattttttcc 3612721 agttgtcata taggaacgtt cgttctataa taaaaactca gtattttatc ctattatcgt 3612781 catttaacat cttttcgtga aggctttttc ataaaaaaac ctcattcttt ttcagaatga 3612841 ggtttgtgaa atcagcttag tttgcgttta ggaagcttgt ccatattatc aagcatgaca 3612901 cctgtgccga tggctacgca atccatagga ttttcagcaa cgaggaccgg taccttcagc 3612961 tcttcagcaa gcagctggtc aaggccgttt aagagcgcgc ctccgccggt aataataacg 3613021 ccgcggtcaa taatatcagc agaaagttca ggcggtgttc tttcgagcac ttgttttgca 3613081 gcctgaacaa taacagcgac agattcacga agggcttctt caacttcttt actgtttact 3613141 gtaattgttc ttggaagacc ggaaaccatg tcccgtccgc gaatggaaat ttcctcgtga 3613201 cgtgcgtctg ggaaaacagt tgcgacttta atcttaatat cctccgcagt acgttcgccg 3613261 atcagcagct tgtactcgcg tttgatataa tttaagattt ccatgtcaaa cttgtcccca 3613321 gccattttaa tagaagagga ggtgacaata tcgcccattg aaataaccgc gatatccgtc 3613381 gtcccgcctc cgatgtctac aaccatgtta ccgcttggct ggaatatttc catacccgcg 3613441 ccgatagcgg caactttagg ttcttcttca aggtacacat gtttcccgcc gcttttttct 3613501 gcagcttctt taattgcttt ttgctcaacg gatgtaatat tcgtcgggca gcaaatgagc 3613561 atgcgcggct ttgagaacag gccttttaca ttcagcttgt taataaaatg tttcagcatt 3613621 gcttctgtta cttcaaagtc agcaataact ccgtctttca gcgggcgaat cgcaacaata 3613681 ttcccaggtg tacgtccaac cattcgtctt gcctcttcgc caaccgccag cactttgccg 3613741 ctgtttttat caagtgcaac aacggaaggt tcattcagaa caattccttt acctttaaca 3613801 tggatcagta catttgcagt accgaggtca ataccaatat cccttgcaaa catctattta 3613861 tatcctcctt gaaaatctgt ttcacagtaa atatccacat tgtgccctaa ttatatatat 3613921 tatcataaaa tatagaaaaa aagttggaag cacaataagt tctttacaaa tttttgcgga 3613981 tgttttatga acgatttcaa gaaggcaatg ccaggtgatt acgattgctg aacaggctct 3614041 ccttcgagaa tttcatcttt tttatatttg agctttgtcg cttctcctcc tcttaaatgc 3614101 ctgatggatt tatgataatc gagtatttct ttcacttcgt ttgccaagtc ggggttaatt 3614161 tcaggcagac gctctgttaa atccttgtgt actgtacttt tggaaacacc aaattccttc 3614221 gcaatgacac gaacggtttt ctttgtctcc acgatgtact tccctatctt gattgttcgc 3614281 tctttgatgt aatcgtgcac accactcgac ctccctaaaa tggatgtgag aagtgtgaaa 3614341 tgagatccgt attctgtaaa gagtcgttca ttatgccgct tcttcgttgt atggttttaa 3614401 aagtaagttt gtgaaatatg cccacgatcc ctcacctcaa acactctctt tgttaggttt 3614461 gtaacagtgt attagcattc ttttgggaat atgctaaaaa ctcaataagg acaaggggtg 3614521 aaacgaactt tttcagattc agcaaactat ttcgcgtcac taaattttca tctttacaac 3614581 tattgatcgc tcctgtaaaa tgaaataagc aattagttac ttaggtaagt tttttagaag 3614641 gagaccgaca tgtcctacgt caacagacac ctcattcatc aaatcaacca aagcgcccgc 3614701 ctgattgcca agaaagccaa tgaacagcta gagccattcg gcctttattc atctcaatgg 3614761 tcagttttat attgtttgcg tacgatcgga ccaatgactc aaaaagagat ttggtcctat 3614821 ttaaatgtgg aagcgccgac tgtgactcgg acgatcaaac gcctggagga gaacggctgg 3614881 gttcagagac ggcaaggtga agacaaacgg gaaaaacttg ttgtcctcac aaaagaagcc 3614941 gagaaaaaat acgaagaaat caatgtgaaa atgttgaaat tcgaggaaga gctgcttgca 3615001 gatttccggg atgaagataa agaagctttt tctcatttat tccgcatgtt tttacaacaa 3615061 tgaaaataag gaagtgacat acatttgaaa aaagcggatg cgatatggac caaggatttt 3615121 attatggtcc tgcttgtcaa tttatttgtg tttgtgttct tttatacatt tttaactgta 3615181 ttgccgatct atacactgca agagcttggc ggcacagaat cacaaggcgg gcttttaatc 3615241 agcctgttcc ttctgtctgc gatcattaca cggcctttct ccggagccat cgttgagcgt 3615301 ttcgggaaga aaagaatggc gattgtatca atggcgctct tcgccctatc atcttttctg 3615361 tatatgccga ttcataactt ttccctgctg ctcggattgc ggttcttcca agggatttgg 3615421 ttcagcattt taacgactgt tacaggtgca attgccgctg atattattcc agccaaacgg 3615481 cgcggtgaag ggcttggata ctttgccatg tctatgaacc tcgctatggc gatcgggcct 3615541 ttccttggcc tgaatttgat gagagtggta agctttcctg tattctttac agcctttgcg 3615601 ctgtttatgg ttgcgggctt acttgtttcg ttcttgataa aagtgccgca aagtaaggac 3615661 agcggcacga ctgtattccg ttttgcgttc tcggatatgt ttgaaaaggg cgcactcaaa 3615721 attgcgacgg tcggtttgtt tatttctttc tgttattcaa cagtcacatc atatctgtct 3615781 gtattcgcca aatcagttga cctttcggat atcagcggat atttctttgt ttgttttgcg 3615841 gtgacaatga tgattgcacg cccgttcaca gggaaattgt tcgacaaagt cggaccgggc 3615901 attgtcattt atccatcaat cctgattttc tctgtcggac tctgcatgct gtccttcaca 3615961 catagcggct taatgcttct gctttcaggg gcggttatcg gtcttggcta cggatcaatc 3616021 gttccttgca tgcaaacatt ggcgattcag aaatctccgg ctcaccgctc cggttttgcg 3616081 acggcaacgt tctttacctt ctttgacagc ggaattgctg taggatcgta tgtattcgga 3616141 ttgtttgtag catctgccgg cttctctgcc atttatttaa cagcggggct gttcgtttta 3616201 attgctctgc ttctctacac gtggagccag aaaaaacctg cagaggctga aggaaaagtg 3616261 tctattgcag aataacttgt cagactgccg ggaaatcccg gcagtctttt ttccattaaa 3616321 acacggcgcc ctctcggttg aacgagagaa cgccgcttat agcaattatt caatgacagg 3616381 ccgcgcaggt gaatcaggat ctaacgaaaa atcataggac gcttcatcac gaaacatcgg 3616441 atcggcatat atggattgtt gatcgttttt tgttgctttt cgatacgaag aaaatgaatc 3616501 atattctttc tttttccaca tccatatgcc gtcttgatcc gcttccttgt ggtacacgtt 3616561 atgattgacc gtattacctt cgttttctgt aaagtcgttt ccgataaata atctggaatc 3616621 accggccgtc aatatattct tttcaattgt gttgtttttc gtatcgtact gcagcagcag 3616681 ctgtccgccg tacagtccct ttgtgtcatt ccggtacata atattgcggg caatcagaga 3616741 attgctggtg ccgccccgct ttttgtcata tcctccgatt gaaataccgg tgtacgcatt 3616801 gttgtacact ttgttgtctg tgatctgaat ggcatttgca tactttcctt tgtgttcaga 3616861 cgttgcttca atcccaatat cgttatcgta aactgtgttg ttcttaattt cgatatcgtg 3616921 tcctccatcg acataaatcc cgcccgctga gtattcatct ccataagcag gattgccgta 3616981 agtcgagttt tgataaactg tattgttttc tacgactccg tttcgcacgt aatcgttttt 3617041 atccgcggtt ccctcataac caattagatc aatcccgatg ttattattgt tgcggaccac 3617101 attgcctgca actgtgaagc cgtcgatatt accgttcagc acaactgctt cactcgctcc 3617161 aagcgtcagt ttctcaactg tattgtcctc gattcggatg tctttcatgc tgccagtccc 3617221 ataaactgcg attccgtgag catttccttc atccgctgtt gtcttaatcc cccggatgtg 3617281 attatcctta atggcgatat gactgctgga ccctgataca taaatcccta tagcagttgc 3617341 ttcctcagat gaaacagaaa gatcttgaat tgttaaaccg ctgatggcaa tgtcatgttt 3617401 atcgtgaata cgaataagcg gtgtttcata ttcagcgttc gcaacggatt caccgctaat 3617461 cacgacgttt tcattttcat agtttcggaa tgtgataggc tttccgtccg taccgctgtg 3617521 ctttacatca agggtctcat gatacgtgcc ctcccgaatc atgacagttg tgccggcagc 3617581 agccttctca gatgcgtgtg ccaatgtacg aaacggcttt tcttttgttc cttcattttg 3617641 atcactgcca tttggcgaaa catacagata atccccagat ccttcctcat tcgcttttgt 3617701 cttatcataa acgaaagcga ggatgacaga cgttaaaaca cccgccaaaa gaataaaata 3617761 ccattttctc attttcgatt cccatttcgt tttagaatag atttctaaaa ccattataaa 3617821 tgttctattt atggaaaacc atttcaaaaa tatgaaaata taccgtctaa atagatctta 3617881 ttcagcctgg cggacctgcg catgttcaac tgtttcaatt gccaatgatg caggcgggtg 3617941 aacacgcatc agaacaatgt agaaaagaaa ggaaatcagc acacctacaa accaagaaat 3618001 atcgtataag ctcttcaata caggaacata catgccaatc agcgaaatca gcgctcctaa 3618061 cattgtggct gcaaacgcac ggtaattgta gcccttccaa tacacatacc gtcctgtttc 3618121 ggaatacagg tcatctaccg agagctcacg tttgcgaatg ataaaatagt cggccatcat 3618181 cacgcctgcc accggtccaa gcatgccgcc tattaagcca agaaacgcat acacgcttgt 3618241 cgcgctctcc atcagcttcc acggaaccgt aaataaagcg agcaacgctg tgataaagct 3618301 gccacgtttg aaattgatat atttcggcag ggcattcgct atatcataag cgggtgatac 3618361 gatattcgcc gcgacattta cagagatcgt ggcgatgcag agtgtgatca cggacaagac 3618421 gatgacataa gggttatcaa accgcgccaa aatatcgaca acatcccaaa tcggctctcc 3618481 gaacgcgacc tgcgagccgg aggtcaccgt aatacttgcg aatgcgaaca gcgcaaacgt 3618541 tcccggcaaa ccgtaaaatt gtcctttgat ttgctctttt tgtgtttcag caaaccgtgt 3618601 aaaatcaggt atatttaaga tcaatgtcgc ccagatgccg atgatgccag taactccggc 3618661 agcaaacggc cagaatgttt ctgaaaacgt atgaaacttt cctggttgag agtatatcgg 3618721 gcccaatcct ccagcaatat caacggccca ccataccatg ccgccaaata ccagatacac 3618781 taaaggccct gcccacacct caaaacgttt aatcgactcc atgccgtgat gcaatacgag 3618841 taaatgaatg gcccaaaaga atacaaagga aagcaaaccg gacaagtgaa tgccgagaat 3618901 gttccactcg ccgccaattt ctccccaacc tggccacata ttcaaaagca aaatgttcag 3618961 tgccgtgcta cccgcaaagg tctggatgcc aagccacatg atagctgtaa acgcccttag 3619021 aagcgcgggg atattcgcgc cgtatatccc gtaagaagcc cgaatgatca ctggaaacgg 3619081 cagcccgtat tttgtccccg catggccgtt taaggcaaga gcgccaaata ggataagtga 3619141 tgccgtaata atgatcgcca gcacctgcca aggcgaaagg ccgatcgcaa ttaatcctcc 3619201 cacggtcgcg taggtcggta tgttatgtat acatcccatc caaatggagg caaagttcat 3619261 tgctttccac gtccgttttt cctgtcccaa aggcaccaga tcttcattgc tcagcctgtt 3619321 ggattgctgc tgactctctt ttaatttcat agccggctcc cctttccata ttgtctatat 3619381 gtcgtcacac gttatgtttt ttgacattag atgtcactta atataactga agagtcagac 3619441 aataacactg gctatgatat acaattttcc cgtttgtatt tgaacagctt aaacaagaaa 3619501 aagagacaga cctcagagcc cgtctctttc ttaagatgca gttttcatta atgcagcaaa 3619561 tctcacagcc attaacaggc ttgctccgcc cgctataatc ataatgattc ccatcatatc 3619621 aaaatgggct gccgtgattt ctttaccaaa aagaatgcca aggatcaccg aagacaaaat 3619681 cgatcctagg taacggcagg tttgaaacag gcctgaagtc gttcctacca tgttggaagg 3619741 actcgtttcc agcatcgctg cctgaagcgc gacattgccc agtccgtagc ctatacccaa 3619801 gagcgacaga atgaggcctt taccgatggt ctggacattg ataaaaaaga tggttaagag 3619861 cacggctcca gccgtcatca aaagcgctcc cgcaaagatc ggcttgacga caccagatcg 3619921 gtcgatccat ttgccggtta gaggtgacac aacgatgctc attccagaca taaacagcat 3619981 aaacaggccg ctcgtttgaa cagaaagatg catttcatcc tgaaagtaac ttggcaaacc 3620041 aaaaaataaa caatagaaga aaacattcaa taaaataaac tgaacataca cggctgacag 3620101 gtttcgctgt gttttaaaca gacggacatc aataaacggc ttatccgttt tcagctcgcg 3620161 ccagacaaac gcacagagca gaagcaagcc aagcacacct tcaaccgcat gcggcgacgt 3620221 gctgaacgac agcaaaaagg atagaaggaa aatgattccc ccggcaaata aaacaattcc 3620281 aagaatatcg agctgccgaa taatggtttt gattcctgcc ccttttttct gatctttcgg 3620341 gaacatatac aggcccaata agaagctgag gataataaac ggcaaattaa cgataaagat 3620401 cgccggccag cctccccata caatcaaaaa cccgccggct gtcggcccca gcgccgtcat 3620461 ggcggacgca aaaatagaga gtacagccaa ggctgaagct tggcgctcat gaatatgatt 3620521 ccgaatcaag ccgacacctg acggataaat cgcactgctc cccaccgatt gaaacagccg 3620581 catgaccaat aatgtcataa acgtcggcgc aaacggcgcc ccgatggcag aaaccgcaac 3620641 aagaataagc ccgaataaaa acaagcgttt ccgcccaatc aaatcaccga gctttcccgt 3620701 tacgggctgc gctacggcac tcgccaagta aaacgaggaa atcagccagg aaaccgttgt 3620761 aaacgagagg tgaaactcat gctggatgct atggagcgca agagagatca tagacgagtt 3620821 cagcggattc agcattgttc ccgaagccac agctgttaaa aaaacagctc ggcttttttt 3620881 cgataacatc atttcacttg ttccagaaac tcttccgttg tccgcgattt accgattctc 3620941 gggaaaataa agcgcagtgt ggcttcatgc tcttcatcgc taaatgtgga catggcatct 3621001 gtaataaaaa tctgctgata gccaagctga aatgcctccc gtgctgtgct ttccaccccg 3621061 atattcgttg cgatgccgca caatacaatc gtatcaatgc cgcgacgtct cagctgcaag 3621121 tctaaatctg tgccaaaaaa agcaccccat tgccgttttg tcacagtata atcgccatcc 3621181 tgcacaccga tttccggaac aaattcggcc cagtccgccg gcatttcccc tgaacctccc 3621241 tgcgcaggct catccgtttg cggcttcagg gcgtccgctc catcatgaaa ggctacattt 3621301 acaaagctga tgaacccgtt atgtttccga aattcatcta cgagcttttt cgcgttcggg 3621361 acaacctggc cgctttgatc aatcggcaca attccctttt gtaaatcaat gataaccaat 3621421 gctgtttttt gaaaatcaat gttgagtgta ttcatcatac gtctcctcct gatactgtta 3621481 gtgtttctca cattgcatat tttactcttc acactgccta agttctttta tgatgcttgt 3621541 gaaattctca gaaggagcgt tttctcatga tttttctttt atgtagtagt aacaggttgt 3621601 gcatacgaac aaaccggcaa gcactgtaat cataaagggc gtcatcgctt catcacctgc 3621661 ctgctgtcta tcggttcctg cctgaaaatg cccatgaatt tgcggcggtc catccaaagc 3621721 aggataagac acataaccat taatatcgtg ctaagatcct gcacgccaat atcaaaacaa 3621781 tagttaatca agacgatgtt cacaataatg ggcataaaaa taaccgcccc taatgcagcc 3621841 gttcgcggaa tcagtaataa aacagctgcc aggatttcac caaaacctat aaacagttca 3621901 tagacatgag aataaccgaa aaatgtccac gcgatcgtaa accccttccc ggcagccgcc 3621961 tcgatttcag gcgtcacctc gccaaactgg ccaattacca ctttcgccag accgtacacg 3622021 aaaaaattaa aggctaaaaa caatcggaac gtcgcgggaa tcgacttgcg taccgctttc 3622081 ctcagcctgc cgcctttatt catcatacat ccccctcagt gtattatttg atgtagtaca 3622141 cttaatacag tatagagtat tctaattaat gtcaattccc ttttcagctc atatgaatag 3622201 tttcttttat agatacaaag tcttatatcg caaaaaatgc cattctcctt cctttccatc 3622261 cctcgataac atttctcaaa aaccatgtca ggaaatctta catgaaaatg ttttatcatt 3622321 cttttttctc tataatgaag aaatataata attgcttttt attctgaaag atacggagga 3622381 atgagacatg caaatgggcg atacagtttt tatgttcttt tgcgctttac tcgtgtggct 3622441 gatgaccccg ggattagcgt tattttatgg aggaatggta aagagcaaaa atgtgctgag 3622501 cactgccatg cacagtttct cttccattgc catcgtttcc atcgtttggg tgctgttcgg 3622561 atatacactt gccttcgcac caggcaattc aatcatcggc gggctggagt gggcaggcct 3622621 caaaggggtc ggatttgatc cgggagatta cagcgatacc atcccccact cgttatttat 3622681 gatgttccaa atgacgttcg ccgttctgac tacagcgatt atttccgggg ctttcgcaga 3622741 gcggatgcga ttcggcgctt ttcttttatt ctcggtttta tgggcctctt tggtttacac 3622801 acccgtagcg cactgggtat ggggcggcgg ctggatcggc cagcttggag cgctcgattt 3622861 cgctggcggc aatgttgttc atatttcctc cggggtggca ggacttgttc ttgccattgt 3622921 gctcggcaaa cggaaagacg gtacagcgtc ttctccgcat aacctcattt acaccttctt 3622981 aggaggagct ttgatttggt tcggctggtt cggctttaac gtcggcagcg cattgacctt 3623041 agatggtgtg gccatgtacg cgttcatcaa cacaaacacc gcggctgcag ccgggatcgc 3623101 cggctggatc ttagtagaat ggatcattaa caaaaaaccg acaatgctcg gagcggtatc 3623161 tggggcaatc gccgggcttg tcgccattac gccggctgcc ggatttgtca caccgttcgc 3623221 ttccattatt atcggcatca tcggcggagc tgtttgtttc tggggagtat tctcgcttaa 3623281 aaagaaattc ggatacgacg acgcgcttga cgcctttggc ctgcacggga tcggcggcac 3623341 atggggcgga atcgcaacag gattattcgc aacaacctct gttaactcag cgggcgcaga 3623401 tgggttattt tacggtgatg caagcttaat ctggaaacaa atcgtcgcca tcgccgccac 3623461 ttatgttttt gtatttattg tcactttcgt tattattaaa attgtaagcc tcttccttcc 3623521 ccttcgcgca actgaagaag aagagtcact tgggcttgac ttaacgatgc acggggaaaa 3623581 agcatatcaa gattctatgt gaggagtgac gctatgagcg gtcaaatgtt caaggtagaa 3623641 attgtaacgc gtccggcaaa ttttgaaaag ctgaagcagg aactcggaaa aatcggagtg 3623701 acctctctga ctttctccaa tgtacacggc tgcggccttc aaaaagcaca tacggagctc 3623761 tatcgagggg taaaaataga aagcaatgta tacgagcgtt taaaaataga aattgtggtc 3623821 agcaaggttc ctgttgatca agtgacagag accgctaaaa gggtgctgaa aacgggatca 3623881 ccaggtgacg gtaaaatatt tgtctatgaa atcagcaata cgatcaacat ccgcacaggc 3623941 gaagaaggac ctgaagcact ttaatatcgg tacgagattc ggacactccg gatctctttt 3624001 tttgtgcaca gaatcccccc agaaaccgcg attcctcttc gaattctctt caagcgccgt 3624061 tatttcagac aatctctatt tttatttgaa acttttcatg agtaagatta gtctactaaa 3624121 tataaaaatg taaaaggtga ttatttgaac tacgaaattt ttaaagcaat ccatggacta 3624181 tctcatcaca attcagttct cgattccatt atggtcttca tcacggaata tgccattgtc 3624241 gcctatgccc ttatcctatt ggcaatctgg ctgtttggga acacacaaag cagaaaacat 3624301 gtgctatacg caggcatcac aggaattgca ggccttgtga tcaactattt gattacgctt 3624361 gtttatttcg aaccgcgccc gttcgttgcg catacagtgc atacactgat tccgcatgct 3624421 gcggatgctt catttccaag tgaccatacg acaggtgcat tagcgatttc tattgcgatg 3624481 cttttcagaa accgcaaaat cggctggccg cttgtcattt ttgggctttt gacaggcttt 3624541 tcgagaattt gggtgggaca tcactatccg gtagatgtat tgggcagcct cgttgtcgcc 3624601 atcattatcg ggttcctttt ctttagattt tcagatctgc ttcgcccgtt cgtcgatttg 3624661 gtcgtgagga tctacgaagc cattatcaat aaactgacga aaaaaccaac cgatcaaaat 3624721 ttctaagaaa gacaaaagcc ggcgtctgaa atcaagacag ccggctttaa tatttctcat 3624781 acatctcttg ttttcttcgc ttcgccaaca catataaacc ataaaacaac ccaattccaa 3624841 cagcatcgat gagcacatcc cggatacaac cattcctgct gaagaagagc tgaagaactt 3624901 ctgtgaaaaa agcaaacgca aatgagccgg ctgcagctga tcttatgctg ccccgctgtt 3624961 tccacagcaa atatgtcagc acaaagaagg aaaacgcgtg tccgattttt tgaataaacg 3625021 cttcaggtac agtaagctca gtaaaatcca taactaaaaa ttgagacaga tcagggtgcg 3625081 gctgaaaatg aaaagccacc gtttgcgata cgaccatgcc gctgaagctt tccgtacaga 3625141 cagaaagcag gataaaaaag atccagcctg cgagcaatag gcggttcatg acataacctc 3625201 ctttataacg tacgtgccta catgtaacta catagacggt aaaacaaagc aaaaagtaac 3625261 agaaaaaaac gcccatcaca aggatagacg ttttcttcat taagactgtt cagtgtcttc 3625321 tgttgtgctg ctttctttag aaccagattt gtcagttgaa tcatcctttt tctcaccgga 3625381 tttttcttct gttccttttt cagttgatcc gtcctttttc tcggaagatt gctgaatgga 3625441 ttcttctgtt tcttgggtgg cagctttttc aatagaagaa actggtttgt ccataaagtt 3625501 taacggattc attgcaaccc catctttacg gatttcaaag tgcacgtggt ttccgctgtc 3625561 ttcactgtaa aggttcttgc cagattttcc gatcacttga ttttgtttta ctttgtcacc 3625621 ttgctctacg cttacttcgg aaagagattg atacacagtc gataaaccgt cggcatgttc 3625681 tacttccaca acatatccca gcactggatc tttttcagct ttaacaaccg taccgctcag 3625741 agaagcagag acatcgaaat cttttccgtc tttctcagct aagtcaattc ctttgcttag 3625801 gctgtacgtg ttattatagg taacgagtgc tgcttctttc tcttcttttg cggcatcggt 3625861 ttcatagaac tttttcacaa cagaaacgtt ttcagaatca acaaccggca ttgcgacatt 3625921 ttccattgac tttcctactt caactgcatc gtcgttgttg tcatatgcgg agtttccgcc 3625981 gttatcagcc aactgatcct ttacctcatc atttgatact gattgatacc aaaggacagc 3626041 tgttaaaatg acggccgcac tgactaagta aattgcaggg aacacccagc gtttacgaaa 3626101 aaactgctga agttttttga cttgagaagt tttcttttct tcctctctca ttgtttcatc 3626161 acctcagcaa cattctgaac acttttctga aaatatatac aacctatcca aaaaaacttt 3626221 tttagatgta gtttgcacag actgaacgaa aatatgtatt tttttgagag gagtgccaaa 3626281 aacgtatgaa catgacattg cgtcttgctg aacatagaga cttggaggct gttgtggcga 3626341 tttataattc aacgattgct tctcgaatgg taacagccga taccgaaccg gtaactcctg 3626401 aagaccggat ggaatggttt tcgggacata cagagtcacg tccgctctat gtggccgagg 3626461 atgaaaacgg aaacgtcgct gcctggatca gctttgaaac attttatgga aggccagcct 3626521 ataataaaac agcggaagtc agcatataca ttgacgaagc atgccgcggc aaaggtgttg 3626581 gatcatattt gcttcaagaa gcgctccgca ttgccccgaa tcttggcatc cgctcactta 3626641 tggccttcat tttcgggcat aataaaccaa gcctgaagct gtttgaaaag cacgggtttg 3626701 cagaatgggg actattcccc ggcatcgccg aaatggacgg gaaaagatac gatttaaaaa 3626761 ttttagggag agagctttca tgattagtct ggataaagat gaaaacgaaa ttgaacatca 3626821 taatgaagaa aatagccttg ttgaacagga gactgcacct gttggacagg agagccgcca 3626881 gctgagcgcc tccgctgtca agtcgctatc cgacattgcc aagtggggca aaatttctgg 3626941 catcttgtta atcattatgg gatcgcttgt cactctgtct gttttgatga cagtgattgg 3627001 cgccatcccg ggcgtactgc tcattatttc aggcgtattt ttgatgcgct cagcaaaagc 3627061 agccgcggaa gccgaaggaa atctaaccgg cagcgctggc gaaagcatgc ttgaaaatta 3627121 cgggacattt ataaaaatgc agctgtttta tgcagcatcc agtatcgtta ctgtcctgat 3627181 cgggatcatt gtagccattt tcgtgctggt ggtaatcggc attgctgctt ttgagaacac 3627241 gccttcgtat gatgatccgg attcttatta ttatgaggat gatccggtgt ttgaataatg 3627301 atgagacagg acagggcatg agttccatat aaacggaacc atgcctattt tatttgacta 3627361 ttcaaagcag gccggcgtaa acaccaaatc ctgaagcaag catacaatag acatctctag 3627421 tagaggaaat caacaaagca acgctgttac ccagaaatga atatcaaaaa aacggatgaa 3627481 gtcggaatca atccgaaacc gcacttttta tttcgggtgt ctgcatgcaa aaaaacacac 3627541 ccggatcgtc tggaaaatct caacaatccg ggtgcagatc ttctttaata catttttttg 3627601 cgtctgtctt cctcagtcaa aaattcaaca aaactccgca tcgcaaaagg ctcttccttt 3627661 atttgtcgtg cgtaggagct tttccgctct tctgaaagga tttcgctctt tttgatcctg 3627721 ttcagcatat agatgtgaac cgttttttgg atttgtttat gctgatagcc tgcctcttta 3627781 aaaaatgcga gcccgagcgc cgccaaaagg gcgaatatgc ctgcgctgat cagggactcc 3627841 ctgtcagctg aagcatgaaa tagaaaagca gctaaattaa agagagagaa tgcagcaagc 3627901 ggaatagcaa gaaaacggta aatgacggtt tttttcatga aaggctgtac ggccttttga 3627961 attttttgca tttctgtttt gatgaacccc ggcatttgtt cgactctgta aaagttcata 3628021 taatcctccc cctttatttg atgtttcaag cttcacgaac gttatcatat gtgtttattt 3628081 taacgcaggt gcaagctggt tttaaagaaa tctgcccgta tttttcacga agaatctgga 3628141 tcgccgctct ttattctttt aaaatgtgag tgttataatt tgtaatggga atcagatcac 3628201 tgttattcat ggaatactaa tggcaatctt cttgataaat atgaatgagc ggggttacaa 3628261 agtgagtatt tcttccatcc ttttatcact ttttttcatt ttaaatattc ttttggccat 3628321 cattgtcatc ttcaaagaac ggcgcgatgc cagtgcatct tgggcgtggc tgcttgttct 3628381 tttctttatt cccgttttag gctttatttt atacttatta ttcggccata atctcagacg 3628441 caagcatttg tttcaatggg aagaccggaa aaagattgga attgaaaggc tgctgaagca 3628501 tcagcttgaa gatttagaaa ccaagcaatt tcagtttaac aaccgggcaa cctttgataa 3628561 caaagattta atttatatgc tgattatgaa taaccatgct gtgtttacag aggataattc 3628621 agttgacgtc attacagatg gacgggataa atttcagcgg ctgctgagtg acatttcaaa 3628681 ggctaaggat catatccatt tacagtatta tatttataaa ggcgatgaat taggcaaaaa 3628741 attgcgggac gctctcatcc aaaaggcgaa agaaggtgtt caggtcagag tgctttatga 3628801 tgaactcggg tccagaacgc tgagaaaaaa gttttttaaa gagcttcgcg aggctggcgg 3628861 gcatgtggag gtctttttcc cgtcaaagct caggccgatt aacctgcggc tgaattaccg 3628921 gaaccatcga aagcttgtga tcatagacgg tatgaccggt tatgtcggag gctttaacgt 3628981 cggagatgag tatctagggc ttaatccgaa attcggttat tggcgggata cgcatatccg 3629041 gctgcaagga acggccgtgc acgccatcca aacacgattc atccttgact ggaaccaagc 3629101 ttctcatcac catacgctga catatattcc aaatcacttt cctgattacg gcccaaaagg 3629161 caacgtcggg atgcagattg tcacaagcgg ccctgattcg gaatgggaac aaattaaaaa 3629221 tggctacatc aaaatgattt cgaacgccaa gcgttccatt ttgatacaaa caccttattt 3629281 tatcccagat gcaagcctgc tggatgcttt aaggatcgct tgcctttcgg gcattgacgt 3629341 taacattatg attccgaaca agcccgatca cgcctttgta tactgggcga cactttcgta 3629401 tatcggcgat ctgctgaaag ccggagccac tgtctatatt tacgataacg gctttattca 3629461 cgcgaaaacc atcgtggtgg atgacgaaat cgcttcagtc ggcacagcga acattgatgt 3629521 ccgaagcttc aggctgaatt ttgaggttaa tgcatttatt tacgatatca ccattgctaa 3629581 aaaactggtt tcaactttta aagaagattt gctagtatcc agaaaattca cctatgagga 3629641 gtatctgcag cgcccgttgt ggattcgaat aaaagaatcc gtctcgcggc tgttgtcgcc 3629701 gatcttataa gatgcgtaaa cccccggcct ttacggccgg gggttttcct gatggtcaca 3629761 gtaaatgatg attgcctccc gcaaaaaagc ggcaagacct tctccatatt gattgattga 3629821 atcggtaaat cgctcgtcag tgatatacac ttccccgagt cctctgaaaa tgtcgagtgt 3629881 gcaatcgtaa tgatattggc aaatatgatc gcgaaatgcc cccacagcgg cctgaatctc 3629941 tgcatcatcg ggcccatgct tcattcgcgc cgcaattcgt ctgtaaatcg aatcaaattc 3630001 agccatgatc gtgcgccaat catctgccga gtatgcagat gtccttttct ctgtttcttc 3630061 tgcgatttcc tttccataca gctttctgac ttcatcagcg tatgtctgct ggtgctcttc 3630121 aatgtctttc atgcttaatc cggcaaataa atccctctta ttcatcgttt cccctccatc 3630181 aacggacaaa agcgtcctgt caattgtttg aatcatctca tccattcttt gttttttctt 3630241 catcaatatc tccttttgcg actgaagtgc cgctttccgg tcaaaattcg gatgatccag 3630301 catctcttta atctcatcca gacgaaaccc gatttccttg aaaaataaaa tctgttgcag 3630361 tctttccagg tctgcgtcac tgtacaaacg atacccagca tcagtaagcg ctgaaggatt 3630421 cagaagctca atattgtcat agtgatgaag cgtccgaatg ctaacgcctg atatctccgc 3630481 cacttgttta acttgatatt tcatacataa cacctcctct tttttatcgt aaacaatcac 3630541 gcaacgttag ggtcaatccc caaaatgtta ttttctatat acaaaacttc tcacaaatag 3630601 tgtataaaag aaaagtgagt atttttttgt aaaggggagc cagtatacat gaatcctgaa 3630661 acaatgaaca aaaccctcat cagcatttcg aaatggggaa aagctacagg cattttattt 3630721 attattatgg gcgcaattac cgcgctttca ggcgcgttct tttttctaat cggtgccgtg 3630781 ccaggcgtac tgcaaattat ttccggtatc tttttgatga ggtcagctag ggaagcaggc 3630841 caaatggctg aacacaatag cggacagtct gaagacttaa tgctggagaa ttacgcgaaa 3630901 ttcgtaaaga tgcaagggat ttatttgatc gtaagcattg ctgtatccat tcttgcgatt 3630961 atcgccttct tcatcttttt aatgcttggg attgctgacg gccttttcag cgatacgtac 3631021 agcacttatt aatgagaaaa acccggagct ggctccgggt tttttattat tccgcttcgc 3631081 ttaccactgt gaagcgttca tttttgtgtt cgggatgttc aagctcgtcc aacacggcaa 3631141 tggcataatc tgcatagctg atatagctgt ctccttttgc atttacgatg acattgtctt 3631201 ttcctttttg gtaagagcca gtccgttttc ctgctggatc aaaaaatgcc gcaggactga 3631261 ggaacgtcca ggaaatggag tctgtctgct gcaaatcttt caggttctcg ccttgatttg 3631321 atgcagttgg caaatattct ttcggaaatt ccggcgtatc cattaaacgg gttgttttgg 3631381 cttcatcaac aaacaggctt cccgctccgc caacaacaag caatcttgtg tgcttcgcgt 3631441 cctttaaaat gctgatgagt gctcttcctg cttcaacatg aagatgttct tggccgggtg 3631501 ctgctccaaa agcgtttacg accgcgtcga aaggcttgat gtcttccgca gtcagttcaa 3631561 acacatcttt ttccaaaatc gctacgtctt gctcctgcac ttttgaagcg tttctgacga 3631621 tggctgtcac ttcatggcct ctttttttcg cttctttcaa aatctcgttt cccgctttcc 3631681 cgcttgcgcc tataatacca attttcattt ttcatttcct ccttatttgt aacaatttta 3631741 gttacatgtt agcggtgaga agtcatccct tttgattaaa agagatgatt cataacatct 3631801 tttaatgact tgcttgccag ttcattttcc atcgctcttt gcacactttc aaacgtttca 3631861 tccagagcgt tctgaatttt tttccctacc ggacatttcg gattcgggtt ttcatgaacc 3631921 gcaaagagtt cttcttgctt ttggacagcc cggtacactt ctaaaagaga aatatcagca 3631981 ggatcttttt tgaggcttgc acccggcacc ccggcgcgtg atgtgagaat atcagctttt 3632041 ttcagcaggc tgatcattct tcgcacaact accggattcg tgttgacact gtctgcaatg 3632101 atttctgaag atgttttttc atccatcgag atgagggata aaatatgaat ggcaacagca 3632161 agacggctgt taatcatgtt ttttcaccac cgttgtaact ataatagtta catttgattc 3632221 gtttgtcaac atctaatata cactaaatac atgggttttg tgcaccgttt ttagtcaata 3632281 gaacggccgg atgcactccg gccgcgtctt atcaaaataa gaaatatctt tgtccaagtg 3632341 ggacataatc gacaggctgg caagacaatt cctccccgtc agcaaagacc tgataggttt 3632401 ttggatcaat ctcaatcttc ggcaaagccg aattcagctt catatccagc ttgctcagct 3632461 ttctgatatt tttgactgga gaaatccttt tttccagccc taagctttcc gccacaccac 3632521 gctctatgct tgcctgagac ataaatgtaa tcgaggttga gcggttggct tttccgtaag 3632581 acgcatacat ttggcgcatg aaaaccggtt caggagtcgg gatggacgcg ttcggatctc 3632641 ccatttgcgc acgtgcaatc atgccgccct ttaagaccag ttccggtttc acgccgaaaa 3632701 ataccgggtc ccacagaacg agatcagcaa gcttcccttt ttccaccgag ccgacctcat 3632761 ggctgagccc gtgcgtaatt gccggattaa tcgtgtattt ggcaatgtac cgttttgcgc 3632821 gcacattgtc attcccgttt tcaccggcaa gagcgccgcg ctgttttttc attttatcgg 3632881 ctacctgcca tgttcggatg atcacttcac cgacccgccc catcgcttgg gaatccgatg 3632941 atgtcatgct gatcgcacct atatcatgga gaatatcctc cgcggcaatc gtcgccgccc 3633001 tgattctgga atggctgaat gccacatctt caggcacttt cgcatctaaa tggtggcaga 3633061 ccatcatcat gtcaagatgc tcatccatcg tattaacggt ataaggaatg gttggcgttg 3633121 tagatgacgg cagaatgttc gcgtaagagg cgagcttcat aatatccgga gcgtgaccgc 3633181 cgcctgcccc ttcaatgtga taagtatgaa taacccggtc cccgatcgcg tcgagcgtgt 3633241 tttccaaaaa gcccgcttcg ttaatcgtat cggtatggat ggcaacttga atatcagcct 3633301 cgtccacgac ttccatacac gttttaatgg cgcttggcgt cgttccccag tcttcatgga 3633361 gcttaagacc gatggcgcct gcttccacct gctcgatcag cggcgcttta tcggatgcat 3633421 tcccttttcc taagaagccg acattgatcg gaaactcctc ggccgcttcc agcatcctcg 3633481 ccatatacca cgccccggac gtacatgttg tcgctttgct tcctgtagcg ggtcctgttc 3633541 cgcctcccaa aagggtcgtc acacctgaag aaagcgcaac ttccatctgc tgaggacaaa 3633601 taaaatgaat gtgcgtgtcc actcccccgg ctgttaaaat tttgccttca ccggaaatca 3633661 cctctgtccc cgctccgatg accatgtgcg gatcgactcc atccatgata tcaggatttc 3633721 cgctttttcc gacaccgaca atccggccgt ctttcacacc gacatccgct ttgacaatgc 3633781 ctgtgtaatc caatagcacg acgttggtga taaccaaatc caaagcgccg tccttccctg 3633841 tgattctgcc gttttggccc atgccgtctc ggatagtttt tccgccgcca aagatcattt 3633901 cttcaccgta tactgtgaaa tccttttcga cttcgatcca taaatccgtg tcgcccaatc 3633961 tgattttatc gcccgttgtc gggccaaaca gttccgcata ttcctcccgt gacattttca 3634021 tcggattaca ccctccatcc agccggcttg ttttaagttg gccaacgttt tttctttgcc 3634081 gcgttcatcg ataaacgtgt cggccattcc gttcagccct ctaattgtct tgcgtcctct 3634141 gatttccact agtgagaccg ttttctgctc tcccggctca aaacggaccg acgtgcctga 3634201 tggaacatca agacgcatgc cgatcgccag ctcacggtca aataataaag ccccgttggc 3634261 ctccgcaaaa tgaaaatgcg aaccgacttg aatggagcgt gatccggtgt tttttaccgt 3634321 tacctcccgt atctcacggc cttcattaat cgtaatggtt ccctcagcaa tttgaaatgc 3634381 tcccggcttc atgacttcac ctccgcagaa attggctgat gtaccgtaac aagctttaca 3634441 ccatccggaa atgtggcctc cacctgaatg ctgtccagca tctcaggcac accctccatc 3634501 acatcttttt ccgttaatac atggcggccg gcttccatca gctctgctac tcccttccca 3634561 tcacgtgcgc cttccataat aaagcaggtg atataagcag cagcctcagg atagttcagc 3634621 agaacgcccc gcgcctttcg ctgtttggct aattcccccg ctgcaaaaat gagcaatttc 3634681 tcttgttcaa ctggtgtcag tttcatctgt agtcctcctt cttttgtcat ataaagcaga 3634741 tgcggctact acgaatttgc ggaacagtca ggcgggacat cacctccctt tcttcgagaa 3634801 tgggggtcat acggtaagat gcctttcaaa gcggcatgcc gtttcttcat cagccttgcc 3634861 atggtcaaca accgttcccc tgtcgatcac ggaaagatca gattaacgcg ttttccagac 3634921 tgcgctcgac taagataaca aatgtctttt tttctggaaa tttctataat aacttgtctg 3634981 actagttcga caattaaaat ctgaattcct tccaattgtt tattaagtaa aatatttttc 3635041 agatttacca tcagcgctct ggtgattgca agctgctgct gttgaccgcc ttttcgtttt 3635101 gaacaaacgt ttgattaaaa caaatagccc cctctgttta gccggagtcg gcctaataca 3635161 gcgacaatct gccccgggcg aagctaaggc tgtgcaaaac catcgattga tcataaccag 3635221 acgttacatt cctgatggca gcccgttgtt ttgctccgca accggaagca tggcatggag 3635281 gccagtctga ggcgccgacc tccacgatac cgagaacccg actattgcca ttaactccgc 3635341 atcatggacg gtcacttcgc tgatcgccac cgttcctctt aatgagtgaa gaattccggc 3635401 cttcactgaa tccccgcttg tgtcgatatc aactgttttc tcgcactccc gtggcttccg 3635461 acactttctt cggtgcagta cattccgtca tcaaaacccc tttgtttgat ttcttcaaat 3635521 gatgttataa aagtttacaa cttatgtcat cattatatag aagaggccta ttaattcaaa 3635581 gaatatttaa aaaatttagt taccttgacc aaatcagctt ctttttttgt tatatttatt 3635641 cacatcagaa aaagcgaaaa aaaagacaag aaacatttcg tttcctgcct cttccgtacg 3635701 attaatcttt atctgaaaat ttatccttgg ctttcccgat atccttttgg atttcgcctt 3635761 ttgccttatc ttttttgcct tcagcctgca tgtccgttct gtcagccata tctccgactt 3635821 tatccttcac ttctcctttg gctttattga agccgccctt cattttgtct tttacactat 3635881 cgttacccat gttaattctc ccctctcaat tatgtgtgta cttgttaact tcccgatctg 3635941 agaggcaata aacattctaa tgttatttat cgatttcgta gcgctctccg taacggagca 3636001 ccttgtatat cgccagcccg tctgatgact ttttctccga atatcggacc ggcagcaggg 3636061 caaaaaacac ataatacgta gaaaaataga caaactgata gaaaaacaca ttcggcttta 3636121 atacactgtg tataatcagc agattgattg caaaaatcgt gatgaggtta aacaagcagc 3636181 cccctgcata cacgagtgca tttgagaatc gattgtcaat tttcaactcc ccgtaccggc 3636241 aaaaagaatc gataaaataa atcgttctga accgtatggg tccaatttta agcagcgttt 3636301 ttcccatgcc tatatccaac gatccctttc cgccaaaaat aaaagccata aagctgtgcc 3636361 ctgaaacatg tataatctgt acaagcggca gaacaatgag gaaagaccac agaaacttca 3636421 ccatatcatt aaaaccaaac attgaattcc ccctcacatg catatctgca tcccaaaacg 3636481 gcttttgttc aaaaaacagt gctgtagcga tttttcctgt tctccccgga aataaacgtt 3636541 ccgatgctcc cctttttttg cataaaaaaa aaccatctgc cagcagatgg ttttgtctca 3636601 tacttcatat aaacaatcgt tcctttgaat catctctctc atgctgaccg ctttttcata 3636661 aaaatacacc gcttctttat attgttcgcg atgactgaaa taagaggcag catctaaagc 3636721 aaattcttca atatatacat acaggccctt ttcttccata taatcaaata cttcttgaat 3636781 catattcaaa ttgacagatt ccacatataa tgcctgcaga aatttatatt ttgccagact 3636841 gaagaagtcg tttcgttttt gggcaatggc aatccctttt tcatagtacc gtatcgcggc 3636901 ttcgctatct tgttttttga aaagaacgcg agtcaggctg aagagcgctt ttggaagctg 3636961 ttccagctga taatcctcga agacaggaag cgctttttca aagtattcgg cggcctgatc 3637021 cagctccccc ttgtcatcat agcaattacc aatattataa agggctgatc cgatcaaacg 3637081 gggctgtcct tccaataaag caaggcgata cgcgtcatct aaatgttcaa gcgctttttc 3637141 ataatttctg tagtcaatgt agtttcctga tatgacgaaa tggcattgaa ttcttctgac 3637201 tctgtaaaaa tcgtgagcct tatacgtctc cagcgcctgt acggcatggt tcatggaaaa 3637261 gtgcgtctgc ttcataatat aaaagacttc cgccacttta aaatgaaatt ccgctctttc 3637321 aatttcatct tctacaaacg caagcatctt ctcagctttc cgataaaagg atatagccga 3637381 gatgtaattg ttctgttcaa attcgtacat tcctctaaac aagtgaaaat aatactcaga 3637441 taatccggag atgctgtcct gattgctttc cagcgttttg atcaattcac gatattgaag 3637501 ctgagattcc tcgtgcaggt caggctttac ataatccagc ataatttggt gccggtagct 3637561 gatcagctga taatacagga gaagcagctg atcctcttcc atctgttcga tatctagatc 3637621 aatttcttct ttcagtttta cggcatcagc cacttgaaat gctaaaatgt gcttatacca 3637681 cttattgatt ttcactccta cttgagatga cgggatctcg tacgcggcca tgcccctcca 3637741 accctttcta ttttctaatt ggttatattt tatcataatg tatggctttg gaattaaatt 3637801 ttcttacaat gattccttct ttatgcctat ccttatatat ttcggttttt ctacgtattt 3637861 tttgcactcg gattctaata aaaaagctta ccggacagtg ccgataagct tttgacttca 3637921 aattaaccgc caatataaga catttccact ttctttttgc cagatgcttt tgatagcgta 3637981 cgatcgactg aatactgatc gatccgattt ttccatactg tcccgatcat ttctgatagt 3638041 tcgtcatcac ttaattcctg gcgaaccgga gctctgaggt caaatccgct tgaagcgaat 3638101 aagcaggtaa acagctctcc tctcgcagaa agacgggctc tgttgcaaga tccgcagaat 3638161 gcatcagata cagatgatat gacgccaatt tctccggagc cgtccaagta gcggaatctg 3638221 gaagccactt cgcctatata attaggcgct atcggctcaa ccggcatgtg tttattgatc 3638281 aaatctatga tttccgcctt tgtcatgacg tctttctttt cccattggtt ggtgttgcct 3638341 acgtccataa attcaatgaa tctcaggata tgcccttttt ctttaaaata acgggccata 3638401 ggcagtatat ctttttcatt gacgcccttt tgaacgacca tattgatttt aacaccgagc 3638461 cccgcttgct tcgccgcttc aatgccttcc agcaccttgc tgacagaaac accgcgcccg 3638521 tttatcttct taaaacgctc gtcttctaaa gaatcaaggc tgatcgtaac ccttttcagc 3638581 ccagcctcct tgagcctctt agcataaaca ggcagcagtg atccgtttgt cgtcatcgcg 3638641 atgtcacgaa tacccggtat gcgggccagt tttttgatta attccggcat atcctttctc 3638701 atgaggggct ctccgccggt caagcggatt ttttcaacgc caaatcttgt gacaaacaat 3638761 gtcgcaagcc gttccagctc ctcaaatgaa agcagctcct ctttctttaa aaaaggataa 3638821 tccgggccga ataattcggc gggcatacag tacgtgcatc ggaagttgca gcggtctgta 3638881 acagaaatgc gaaggtctct cagcggtctg tttcttttat ccaacatctg acgcgactct 3638941 gtaatcatag ctacagcccc ttcctactcc ctgattctct cagggtgtgt atatacatta 3639001 aatgatccgt ttctgacaaa tccaatcgct gtgatattca attcttcagc catttgaatc 3639061 gcaagctccg tcggggccga tttggaaatg acaatcgaca cgccgatttt ggccgctttt 3639121 aacaggacct ctgatgagat tctgccgctg aacacaatca gtttgtcgcg tacggacatc 3639181 ccgtttagaa ggcagtgtcc gtatagttta tcaagtgcgt tgtgccgacc gatatctgtg 3639241 cgcatcaaca gaagcttctc tgtgtcgcaa agcgccgcat tatggacgcc tcccgtatcc 3639301 tgaaacgtcc cgctcccttg ctgcatgtct ttcataagcg ccagacatgc ctcaggcgat 3639361 atcttgattt ggctgacagc cgtcttggct gttttgacat cctgctgaaa ataaaaatga 3639421 cggccctttc cgcagcatga gccgatcacc cgtttcgtat aatccttttg atccaatgtc 3639481 tcagggtgaa cgaggtcgac atatacaaaa ccgagacttt catctattgt aaacctttta 3639541 atttcttttt gaaatcgtat aacaccctct gatgcgagaa atccgatgac aagctcttcg 3639601 atatgctcag gcgtacaaac gagcgtcaca aattcactgc cattcagtat cactgtcaaa 3639661 gggaattccg tcaccatccg gtcttctact ttgcttattt ccccttgttc atagcgccat 3639721 acatccctga ccgcagttac tttatcgttc aatgtctctt cccctccgca atgttcctgc 3639781 ctttatattt tttcacactc ctcggatttt gtcgaattct gagacacaaa aagagccctc 3639841 tatataaagg gcttttacag gatgtgatga cggcggtgtt taggcaggac gcctaagcat 3639901 ttagccgccg ttccttttat aacacgtgag caccaatgtg cattgacaac gaacgcgggg 3639961 tttgtcgaca cgctgagaca cctctgtata aaggactcta tgtttgatta tgctgattct 3640021 ttttcagaac cgtaaacagc acaatagctg cgatcaaggt gagaatgctg acaaaaaaga 3640081 aggctgccag ttttagaaga acaccaagca atataaatgc aacggtggct ataagaaaaa 3640141 tcattccgaa taatttcata tgttcaaccc ctttttaggg tatcattccc gcccaaactg 3640201 tttttaaacc aataaaaaag gcgcctgggg gagcgcctga tctttaggtt ccttactcag 3640261 taaatttttg tgcttctttt tcccaagcct gttcgaactc atccgcactg ttcgctgaaa 3640321 tatattctcc gccgccagcg acagctgctt gtttcatctc ttcattaccc ttgacatcaa 3640381 agttgaagcc aatgatgttt acaatcgtat ccacatttga tgcacggagc ttttcgattt 3640441 ccgccgcagg gtctccgccg cacgtttctt caccgtcagt gattaaatac accacgtttt 3640501 tcccgtctgc gtcaaatgct tcaaattctt ttcttgtgtc tgcaagtgct ttggcaatcg 3640561 gtgtccatcc agtcggcttg agctcactca atgaattgtc aaacagagac ccttcatatg 3640621 gatgaaggcc gtaaatggtt tccgtcgtac tgcacgaaag ggctttaccg gacagtttat 3640681 tgttccctgc atgcccgaaa acgcgaagca taagatttgt atcctttgga agaagttcgg 3640741 caaaagattt tactgatttt ttggcaatgt ctattttgcg ctctcctcct gttttttgaa 3640801 ccatgcttcc gcttccgtca aacaaaacag ctacatttgt atcagcctgt ttctcagcgg 3640861 caaaagacgg ggaggcaatg gaaacagtca acaatccaat gataccggca gccagcaatt 3640921 ttttcatatg attacttcct ttctttttca tattttccaa ctatatgttg gattcttctt 3640981 tatgctagaa tacgaaaatg caaaaagata taggacatgc tgccttttgt gctgctttca 3641041 cgatctgtcc aaaatcgctt gaaatgccgt tcatttttag ccatttccgc ccagaaagca 3641101 taaacagctt gtgtgatcat tcattctttt ttcgccttga ttatgacaga aaaacggaaa 3641161 tctgctacta tgctacaggc agacagctaa ttagttttga agtttttgtt acatacaaaa 3641221 agaggctgac catcaccagc ctcttttttc ttatttagat aacattagtg attgctgagt 3641281 gaaaattttc tcaacatctt tttgggtata agccgggaag tattcaccgc cgcctacttt 3641341 cgcaattgcg ttcagctggc ctttgtatcc ctctttataa tcaaagccga tcacattaac 3641401 agtgatattg tctttttgca gttcctttgc tgttttaatc gggtttcctc cgcacgtttc 3641461 ctcaccgtct gtcaacagat acaccacttt ttcccctttt gcatcaagct ggtcaaaaga 3641521 agatttcgcc tcgttcagcg ctttggcaat tggcgtccag ccagtcggcc caattgtatt 3641581 gagagaattg aggaagcttt gctcgttaaa gctttggaag ccgtatacgt tgcgaatggc 3641641 ttcacatgac tgaacttttc cggaattttt attgtttcct tcagagccaa acacgctcat 3641701 tttcacctga gttccttctg gcaatgagct cgcaaacttt gaaatttctt ttttggctga 3641761 attaaattta gatacaccat ctattctttt cgccatactt ccgctggcat caagcaagac 3641821 cgccacgttc gccggcgctt tagcctccgt ttctgtcttt tcagctgcaa aagcaggtga 3641881 agttaatcca aaaagcaatc ctgtcatcat gatcagtgaa aatcttttct tcatgttcgt 3641941 acccctttac caatttgttt ctgcgtgcag atgttcaacg ctgaacataa tctatcgtaa 3642001 tcaacaaaaa ccgagaaata aatagggcgg gcttccccat tgctgttgtt tacttttgca 3642061 tagaaaccta tgtttttatt agtgatttcc acctaacgcc cctatgaaaa gagaagattg 3642121 tccgcctttc ggctttcgtt atatgagtct gtcgaagtct gtcgacaaat gtggatgact 3642181 ttaccacaat ctcaaagcct gaaatcagga aaaaaggact gatccttaaa gacggtcaga 3642241 agctcctcta aaccgtttca gctactctta gataaaagat attcaggaac agaaaaagac 3642301 gcccaatgag cgtctttttc tactttttcg ccatatattt attcaaaaac gcatctgcct 3642361 cagaaatttg tgtgccttgg taatagtact ttacaatgtc atcaaccgtt ttgccttctt 3642421 tggccataaa attcgctccg tattggctca tccccacacc gtggccaaat cctctcgtcg 3642481 tgactgtaat tgtgtctcca tttcgcttcc attcaaaatc ggcggagttg agacccaact 3642541 tttcacgtat gtctcttcct ttcagcgtct tgccgttaat gacggcagtt gcgacctggt 3642601 ggcccggtgt ctcgccggta atcttcccta ctgcgctaga tccatccagc ttgacgccaa 3642661 gcttttgctg aaattctgcc gctgtaaagg ttttcgttgc cttatatttc ggagactttt 3642721 tatcccatgg gcttttgacg ctttttaaat atgggatagc acttgtccaa taagcttctg 3642781 cattctctgt gtagccgttg cttgtggaga aaaaggatgc ttcaatcggc tggttgttgt 3642841 acgttaagat tttgccttgc gtactggcta ccgcatctgt gattttcttc agttttgtct 3642901 catagcttgt gccccactgt tttttcagct ccgctttgct tttatacacc tggaacatct 3642961 gtgtatcatc caccagtgag cctttaggag cttctaccgc tgaatttgac accatcagtc 3643021 tgacaataaa tgttctggcg gcaagcgcct gggctttcag cgcttcaggt ttaaaggttg 3643081 ccggcatttc ggaggcgacg actccaatca catactcttc aagcggaatg ttttctacgg 3643141 attgatttgc ggttcgatag acgggaatag aaacaggtga tgctttcaat gtttctgctc 3643201 ctttcgatgc tggtttcgtg ctgactgctg tcttttctga ttctacgctg gcccccgctt 3643261 ccttattatg ctggaatggt ataaccaaga gtgtgggaac caagagaatc aatgcacata 3643321 gtacggatag tgtgattgcg aattgtttca tattcagctg cctcctgctc gggattcgac 3643381 tctagtctag tctatgggca gggacaagct aatatgactc tcgttttgga cagaaacttt 3643441 atttgtcatt tacgtattct tttttgctat tttgcgcata atgatgataa tacacaaaaa 3643501 ataaaaaacc agtatgccag agtgacatac tgattttcaa gtaagtttat gcatttaagt 3643561 cagaaacgac ttctttattc tcttgctcag aagcagactc atcatttaca cgttcgatgt 3643621 ctgcgcccag agcggcaagc ttctgatgga aatcaacgta accgcggtct aagtgcttca 3643681 attcagtaac acgtgtgtga ccttcagcca ctaaccccgc aagaatcagc gctgcacctg 3643741 cacgcaaatc agtcgctgca acttcagctc cctgaagctg tacaggaccg ttaatgatga 3643801 cagaacgtcc ttcaatcttg atatcaccat tcatacggcg gaattcttcc gcatgcataa 3643861 aacggttttc aaaaacggtt tctgtaatca tgcttgtgcc gcttgcacga agcagaagcg 3643921 ccatcatttg tgactgcata tcagtcggga agcccgggtg aggcattgtt ttgatgtcaa 3643981 tcggtttaag ctctttcggg ccgatgacac gcagaccttc accttcatcc ttaattgtta 3644041 cacccatctc ttccattttt gcaattaaag aggtgaggtg ctcaggaacc gctcctttta 3644101 ctaatacgtt tccttcagtg attgcagcag caaccataaa tgtgcccgct tcaatacggt 3644161 caggaataat atggtgtttt acgccgtgaa gcttttcgac tccttcaatt ttgatggtgc 3644221 cggtgccagc tccgcggatt tttccgccca tgccgttgat atagtttgct aaatcaacga 3644281 tttcgggttc ttttgccacg ttttccagcg ttgttgttcc ttcagctaga gcggctgcca 3644341 taatcaggtt ctctgtagct cctacacttg ggaagtccag ataaattttt gcgccttgca 3644401 gtcggccttt tacttcagct tcaatgaagc cattaccgac tttgatttct gcgcccattg 3644461 cttcaaaacc ttttaaatgc tgatcaatcg gtctggaacc aattgcgcat ccgcccggaa 3644521 gtgcaactct tgcatgacct gtacgcgcaa gaagcggccc catgacaagc acagacgcac 3644581 gcattttacg aacatattca aaaggtgctt cagtttgcaa agcgtatgaa gcatttacag 3644641 tcacttcatt attttcaaaa tgcacatctg ctcctaaatg acgcaacact tcgttaattg 3644701 tatatacatc ggagagcgta ggtacatcac aaattacgct tttttcttca cttgctaata 3644761 aagatgcagc gataacaggt aaaacggcat ttttagcgcc ttcaactttg actgtgccgt 3644821 ttaacttctg accgccgcgg acgatgattt tttccaaggt attcccctcc gcgtccctaa 3644881 attctctata ttaatattca gtcgtaacga ttggtgtgcc aaccgtaacg gtatgttttc 3644941 cgcccattcc tgcacttcta agtgcaattt gcaaattcat tttatgtttc gaggtcataa 3645001 tgtactcttc ccactcatct gtaaacgcag aaatagaaac gaaatttggc tcaactacat 3645061 gttctactga tcttgcttga aattcattta ataactgatt tgcttttttt tgcaaaacaa 3645121 tattcatatt atcatctaag tgaccattta gacaagtaaa aataactact ttttcttgga 3645181 atatcccaag tgtctcccgt tcaaactgtt catatgtatc attccagcta tccggtgtct 3645241 ctagactcat ttgctcatat aataaatacg aagttggatt gtgttttttg agggttgtga 3645301 caagctgcag tctaaaagaa gtacgatttt ttttgtcagt atatgtgcca attgccttta 3645361 tcattttatc ttcccgtgca atcacccaat catattgacg atactcttgt tttaaacgtt 3645421 gcactttttg ataaaattct ttttcggtca gtgacaagtt ttgttttgca tgcaatgtcc 3645481 acttatctat tgacacatct tgacgttcca tcccctctgc catctgtgct aacggcgtta 3645541 attcactcgc atgaatggta tggaaaacag caatgacgaa gcttaacatg acggaaatga 3645601 taatagcgtg gcttacttgt tttttcttca tgttcatctc tcccccttat ccccagtttt 3645661 accggaggca agaggcgcca tacgtaaaaa tcttcgtcaa aactcgagct attcgcttca 3645721 acccgcttct cccaaccatt taataatgtt caaaacctat taaaatagat agggaagctg 3645781 ctgtgaataa ttgaggtaat ctaaaaagaa attggcaacg gccgttccaa tggcgattgt 3645841 cagcaaaatc atcaggagtc ttgcctgcac gactttgcct tttttgatta acggatctat 3645901 attgacggct tgcaacgccc accaagtcac tgctataaaa atcaggtgaa cgacaatgcc 3645961 gattgcagcc tgctgtccca atacactcat ctattacact cctttctctg cgttcatacc 3646021 ctttcttatt atataagaag cacagataaa gatgatacat tttatacaga acggaataat 3646081 cagccaaatc tagggctaat ccccgcttaa agtgcgattc ttttacatgg tatactttat 3646141 tggaaaggag ctggcaaatg tgaatcattc tttttttcag cctgaaaagc aatatggtga 3646201 ggacctgcca atttttgatc aggaatggga agcaattgca ttctattatg attatagaca 3646261 gtcacagatt gaagaactga atgaattgtg tcagtttttt aacatttctc ttacctatac 3646321 gagagaaagc cttgaagagc ttgaaaacct ctattttcaa agtatacaag aacttttgct 3646381 tgctgattgg aatcttccta ttgaagaatt cgagaaaatg atcagtgttt atcttataga 3646441 ttgtgtgatt gcccgccatg aagatgctga atgggttgta aaaccttatc cctataaaga 3646501 cggcgcttat acacttggct ttagaagaca tcgcaaatcg tggcatacaa tgaatgcctg 3646561 tgatggttta tacctgcgtc caaaagagga tcgcccgttg ctgtcgctgt ttgattctct 3646621 tgtgcgttca taaaaaaatc cttctcataa agagaaggat tttttcttat ttccctgcta 3646681 catccaatct gttcaaagcc cgctgtaacg caagctcagc ccgacgaatg tcagtatcat 3646741 ctgattgaga attcaaacgc tcctgcgccc gctggcgtgc agcttcagcg cgctctttat 3646801 cgatgccttc cgctgtctcg gcagcctggg caaggatggt gacatgatca ggacggactt 3646861 ctacaaaacc gccgctgacg gcaaccattt cagtctgccc gtcttttttc agacggacag 3646921 cgccgatttt aagaggagcc acggttggaa tatggcctgg caaaataccg agatcgccgc 3646981 tttcggctct cacactcacc atttcgatat ccgcatcgta tactgggccg tcgggagtaa 3647041 cgatattgac tttaacggtc ttcatgcttt taccctccta ggaccagatt aaacttctac 3647101 acccatttct tttgctttct caacaacttc ttcgatacgg cctacaagac ggaatgcatc 3647161 ttctggaaga tggtcatatt taccggctaa gatttctttg aagccttgta ccgtctcttt 3647221 tacaggcacg taagaacctt tttgtccagt gaactgttca gccacgtgga agttctgaga 3647281 aaggaagaac tggatacgac gtgcgcggtg aacgacaagt ttgtcttcct cgcctaattc 3647341 atccataccg agaatcgcaa tgatatcctg aagctctttg taacgctgaa gcgttgactg 3647401 tacttcacgc gcaaccgcat agtgctcttc tccaacaatt tcaggagcaa gggcgcgtga 3647461 tgtagatgcc aacggatcaa ccgcagggta aatacccatt tcagttaatt tacgctcaag 3647521 gtttgttgtc gcatccaagt gagcgaacgt tgtcgccggc gccgggtcag tgtagtcatc 3647581 ggcaggcacg tagatcgcct ggatagatgt aactgatcca acgttcgtag acgtgatacg 3647641 ctcttggagc tgacccatct cagttgcaag cgtcggctga taaccaaccg ctgaaggcat 3647701 acggccaaga agggctgaaa cctctgaacc cgcttgtgtg aaacggaaaa tgttatcgat 3647761 gaagaacagt acgtcctgtc cttgtacatc acggaagtgc tcagccattg taaggcctgt 3647821 caaagcaaca cgcatacgtg cgcccggcgg ctcgttcatt tgtccgaata ccatggctgt 3647881 tttgttgatt acgccagagt cactcatttc gtagaaaagg tcgttccctt cacgagtacg 3647941 ctctcctacg ccggcgaata cagagatacc gccgtgctct tgcgcgatgt tgttgattaa 3648001 ttcctggatt aatacggttt tacctacacc ggcaccaccg aacaatccga ttttaccgcc 3648061 cttaatgtaa ggagcaagca aatcaacaac tttaatacct gtttcaagaa tttcaacttc 3648121 tgttgaaagc tgatcgaatg aaggcgcctg tctgtgaatc ggatcctttt tcgcatccgc 3648181 aggaaccggc tcattcaaat caatattttc tccgagaacg ttaaatacac gtccaagtgt 3648241 tacatcacca accggtactg agattggcgc tcctgtatct acagcttcca taccgcgctg 3648301 aacaccatct gtagatgcca ttgcgattgt acggactgta tcatcaccta aatgaagagc 3648361 gacctcaagc gttaaatcaa tacctacttc gttttcactt gcagctggct gtgaaatttt 3648421 aatcgcatta taaatttcag gcaagtgacc gtcttcaaaa cgcacgtcga cgaccggtcc 3648481 taatacctgg ctaacgcgtc ctttcttcat cgctatccct cctgacaaaa tctttctatt 3648541 ctaaagcggc tgctccgccg acaatttccg taatttcttg tgtgatggct gcttggcgag 3648601 cgcggttgta agaaagcgaa agtgaatcga taagttcctt cgcgttgtct gtcgcgtttt 3648661 tcatcgccgt cattcttgca gcgtgctcac ttgctttact gtcaagaagc gcaccgaaga 3648721 ttaagctttc tgcatattga ggaagcaaaa cctccagaac ctcctcttca gatggttcaa 3648781 attcataaga cgccgttctt tttccgccgc cgctgcccaa atcagataac ggcagaagtt 3648841 ttttctccgt tacttcttga gtaatggcgc tgacaaaatg gttataaaca aggtgcaatt 3648901 catcaaacgc accgtctata aacatttgaa tcgtttgacg ggcaagatct ttaatttctg 3648961 taaacgttac ttcatctcca agtcctgtta actcggaaat gatcggaatc tcccgtttct 3649021 taaagaaatc acggcccact cttccgatgg caatcaccgc atactcatcc ttagactgat 3649081 gacgttcttg catggcctga taagcactcc gtaaaaccga actgttaaaa gcgccggcaa 3649141 gaccgcggtc agacgtaatg acaaggtatg ccgttttttt cacttctctg ctgagaagca 3649201 tcgggtgctt cacgttgccg gaaactcttc cgacgtttga cacaacctct tggattttat 3649261 ccatatatgg cacaaatgat tttgcattgt tttcagcacg attcagctta gccgcagata 3649321 ccatctgcat ggcttttgta atctgacttg tttttttcgt tgacgtgatc cttgacttaa 3649381 tatcgcgtaa tgaggccaaa gatttcacca ccttttctct tcatctgcgt aaaaagagag 3649441 aaaaagagaa cctttttctc tcatcagcat tcgagttagt tgcttggtgc aaatgtgcgt 3649501 ttgaagcctt cgattgcagc tttgaagtct tcatcagcag gaaggtttcc tgttttcgca 3649561 attccgtcaa gcaggtcttt atggttttgg tcaaggtaca tgtagtactc ttcttcaaaa 3649621 cgtctgatat ccgccacagg aatatcatcg agatatcctt ttgtcagcgc ataaagaata 3649681 gctacttgct tttcaaccgg aagcggcttg ttcagatcct gcttcagcac ttcaactgta 3649741 cgcgcaccgc ggttcagttt tgcctgagtc gcttggtcga ggtcagaacc gaattgagcg 3649801 aatgcttcca gctcacggta tgacgcaagg tcaagacgca aagtacctga tacttttttc 3649861 atcgctttga tttgcgctga gccgccgaca cgggatacag acaatccggc attgatcgct 3649921 ggacgtacgc ctgagaagaa caaatcagat tgcaggaaga tctgtccgtc ggtgatggaa 3649981 atgacgttcg tcggaatata agcagagata tctccggctt gtgtttctac gaacggcaga 3650041 gctgtaattg atcctgcgcc tttcgcgtcg ctaagctttg ctgcacgctc aagcagacgg 3650101 gaatgaagat agaatacatc cccagggaac gcttcacggc ctggcggacg gcgaagaagc 3650161 aaggacagct cacggtaagc ggccgcttgt ttagaaagat catcgtatac aacaagaacg 3650221 tgcttgccgt tgtacataaa ttcttctgcc attgtaaccc cagcatacgg tgccaggtac 3650281 agaagcggtg ccggctgtga cgcagacgcc gttacaacaa ttgtataatc aagcgcgccg 3650341 tgtttacgca atgtttctac tacgccgcgg actgttgatt ctttttggcc gatcgcaaca 3650401 tatacacaga tcatgtcttg gtctttttgg ttcaggatcg catcgatcgc aacagatgtt 3650461 ttacctgttt gacggtcacc gatgatcagc tcacgctggc cgcggccgat tggaatcagt 3650521 gcatcgatcg ctttgatacc ggtttgaagc ggttcatgaa cggatttacg gtccataacg 3650581 cctggtgcag ggctttcgat cggacgagtt ttgcttgtca gaatcgggcc tagtccgtca 3650641 accggctggc ctagcgggtt tacaatacgg ccgattaact cttcaccaac aggaacctcc 3650701 atgatgcggc ctgttctttt tacttcgtct ccctcacgga tctcactgaa aggtcctaag 3650761 atgacgatac ctacgtttga ttcctcaagg ttttgagcca tacccaaaac accgtttgaa 3650821 aattcgacaa gttcaccggc catacagttg tcaaggccgt gcacacgtgc aataccgtca 3650881 ccgacttgga tgactgtacc tacgtcttga acttcaatat cagattgata attttgtatt 3650941 tgctgtttta tcagcgtgct aatctcttca gctttgatgc tcacttaggt ttcacccctt 3651001 ctatcgattt tccccggcta attgacgttc aatgcgctga agcttcccgc ttacgctgcc 3651061 gtcataaatc cggtttccaa tgcggacttt aataccgcct attaaatccg tctgcacttc 3651121 atttctgatt ctcagtgaag cgactccggc tttttttgca aacacttgtg ataatggtaa 3651181 catttctgca tccgtcagcg gtttcactga atatacgatt gcgtcttctg tttgacgggc 3651241 cacatttgcg agtttgataa actcatctgt gagctcaggg acaatcgcgg cacgatggcg 3651301 gtcaatcaaa agaaaaatcg tattgagtac ggactgtgac aaagagccaa atgcattttg 3651361 aatcagctct tttttcttcg cagccggcac cttcggatgg ttcaacacat cattaagcgc 3651421 tttttcattt tgaaatactt gttttacaac aattagctct tcttctactt gattcagctg 3651481 agcggactca ttggctatat caaaaagagc tgatgcatat cgtttagaga cagctgatcc 3651541 actcatcggc tttctcctac ctctttaaga tagtcctgga tcaatttctc ttgcgcttgt 3651601 tcatccagtt ctttttcgat cactttcgac gcaatcatga cagaaagaga cgctacttgc 3651661 tcacggagag cagaaaccgc ctgttccttt tccttcacga tttcagttct tgctgcttct 3651721 ttcagacgtt cagattctgc acgtgcagcc tgaataatct cttctttttg cttctctccc 3651781 agtttctttg cgttttcgat aagagtttgg gattcctgtc ttgcttcttt taaaagaacg 3651841 cgctgctctt caatcagctg ctgcgcttct ttattttttt cttcagcaga cgtaatttct 3651901 ccagcgatgt ggtcttcacg ctgtttcatt atgtttaata gcggccctaa agcgtatttc 3651961 ttcagaagcg ctaataagat taacatagct aacagttgga acaggatatc tccgccgtta 3652021 aacgacaatc ctagttcaag tggtaattga gacatctact acggcaactc ccttctgcag 3652081 gtttttcttt gctgatccag cagccgcact tgtctctttt cagccggcaa ggcgggatgc 3652141 ttatcagaca taaagcaatg gcgaaggttc tcttggaatg atcttcgcca tttttagttc 3652201 atataaggct tttatgctta gccaaagaac gctaagaatg cgataacgac agcgataata 3652261 ggaagggctt caactaatgc gatacccatg aacataagag ttctcagttc tttacctgct 3652321 tccggctgac gggcaatccc ctctaccgta cgtgaaacaa tcaaaccgtt accaatacct 3652381 gcaccaagtg cgcctaaacc aattgcaatc gcagctgcta ttaaattcat gaaaaagttc 3652441 ctcctttaaa atgttatccg tttggatata atgttttaat gatcatgact gattttatga 3652501 gacatgtaca ccatcgtcag cattgtaaag ataaatgcct ggatagcacc aataaataaa 3652561 ctgaatgctt gccatgccag catcggcaga atggcaccga ttgtaccgac aagaccgaga 3652621 gccacgcttt gcgaataatg gcttgttgct aatcccgcaa gcaggccgag aagaatctca 3652681 ccggcgaaga tgttaccata cagccgcaaa cctagagtca gcgtattcgc aaactcttcg 3652741 atgattttca tcgggagcat gaatggaaca ggtcttaaat agtctttgga atattccttg 3652801 agccctttca tcttcacacc atagtagtgg gttaaagcaa caaccatcac ggctagcgtt 3652861 aatgtaatgg caggatcggc tgtcggagac ttccaccaga gctcatgtcc gattgtaata 3652921 gagaacggca gccccagcat attcgacaca aatatgtaca tcagcaatgt gacaccaagt 3652981 gccaagaagt tagcccctgt ttttaaatcc attgtactgc caataatatt gcggacgaaa 3653041 tcaacaatcc attccataaa gttctgggct tttccgggac ggatcgaaag cgttcttgtc 3653101 gtcaatatag caatcaataa aacaatcaca ctcgccacag taatcatcag aatgtttgtc 3653161 agattaaaag taagacctag aaattctata gttctgtaac catgattcaa agggttttca 3653221 cctctcttcc attgatgaac gtttaagctg gataaaggaa tctatcataa tgacagggta 3653281 tattgtcatt aatccaataa ctgtacttgc catatgaaag tattcgggat ttttataggc 3653341 aacagccaca gcaagaatcg cattgcacca ccgcgctgcg ctcccgagag atcgtatgga 3653401 ctttcctttc tctacagctc tgtcaaaagc attcattctt ctgacgagca gtaaaaaatt 3653461 aaacaaactg aaaacagttc ccagaataag gcctaaaaaa acggttttat acgctgttaa 3653521 accataaccc agtacataca ctgccaaaat gaacaataaa tatttgcgtt gtctgctaaa 3653581 tgtaagcttg ggatcgtcca tcaattatct gtctcctgat gaaaaaataa tgtatagctt 3653641 ggatacggca aaaatcagcg gttaaccctt agtagaagac cttttttgac cggcaaaacg 3653701 ggcctgttcg aaaaaatcat tcatccgcaa gccttgcagg gatgctgttt cattcgctta 3653761 aataaatcct cataatacgg gtttgctgag aggatttaca ttgaggatga ggactataat 3653821 gaaagctatg aaaaccttct cataataccc tcgtttagca tacaatagcc cctaacatgt 3653881 gtcaatctgt ttaaagttaa aaaacttttt atactttacg tctccacaga atgttcacat 3653941 tttcacctat aattgtatac agattcaccg aatagcaaaa aactggataa aaaaatgaaa 3654001 cccccttttg gggatttcat tttttatttt gttccaaaca tgcggtcacc cgcatctccg 3654061 agacctggaa caatatatcc tttttcattt aatttttcat ctagcgccgc aatgtaaata 3654121 tcaacgtccg aatgatgctt ctgcaattct tccacaccct ccggcgctgc tacaagacac 3654181 atgaaacgga tatttttcgc accgcgtttt ttaaggctgt gaatggcttc aactgcggaa 3654241 ccgcctgtag cgagcatcgg gtcaaccacg atgaattcac gctcttccac atcagaagga 3654301 agcttgacat agtattccac gggttttaag gtttctggat cacggtaaag gccgacatgt 3654361 cccacttttg ccgcaggaat cagctttaaa atgccgtcaa ccattcccaa tcctgctctg 3654421 aggataggaa ccactccgag ttttttccct gagatgactt tcgatttcgc agcctgaacc 3654481 ggtgtattga tatccacttc ttccagagga agatcgcggg taatttcaaa tgccatgagt 3654541 gtagccactt catctactaa ctctctaaaa tccttcgtac ctgtattttc attccgtata 3654601 tatgtcagct tgtgctgaat taaaggatga tcaaatacat aaacctttcc catactgtgt 3654661 ttcagctcct tttttattgt cccatcaaca attacacact tctattgatt ctacaaaaaa 3654721 agacattgag tttcaagaac atcgtcaaaa aacccgccgg gcataagccc aagcgggttt 3654781 taggatctta ataatctaat tctttatata aaggaaattt atcagtcaga gcagctacac 3654841 gctgtcttgc ttcttcaagt tttccttcat cttcgtggtt tttcaatgca agcgcaatga 3654901 tagcaccgac ttcttctaat gcgtctccgt caaaaccgcg gctggttaca gcagctgtac 3654961 caagacggat gccgcttgtt acgaaaggtt tttcaggatc atatggaatc gcgtttttgt 3655021 tagacgtaat accaatttca tcaagtacat gctccgcaac cttaccagtc agtccgagcg 3655081 aacgaaggtc aacaaggata aggtggttgt ctgttccgcc tgaaacgagc tggatgccct 3655141 ctttcgttaa ggcttcagcc agacgtttcg cgtttgaaat gacgttttgt gcatatgttt 3655201 tgaaatcgtc ctgcaatact tcaccgaatg aaacagcttt tgcggcaata acgtgcatca 3655261 gagggccgcc ttgaattcca gggaagatcg atttatcaat tttcttgcca aactcttcac 3655321 ggcaaaggat cataccgccg cgaggaccgc gaagtgtttt atgtgttgtt gttgtaacga 3655381 aatcagcgta aggaaccggg tttggatgaa ggcctgccgc aacaagtcct gcgatatgtg 3655441 ccatatccac catgaagtaa gcgccgactt catcagcaat ttcacggaat ttcttaaagt 3655501 cgattgtacg aggatacgca cttgctcctg ctacgataag cttcggttta tgagcgaggg 3655561 ctttttcacg cacgtcatcg taatcaatat attgagtttc tttatctacg ccgtactcaa 3655621 caaagttata ttgaacaccg ctgaagttga ctgggcttcc gtgtgttaaa tggccgccgt 3655681 gggagaggtt catcccaagt acagtatcgc cttgctccaa aatcgtgaag tacactgcca 3655741 tgtttgcttg tgcgcctgaa tgaggctgaa cgtttacatg ctccgctcca aagatttcct 3655801 tcgcgcggtc acgggcgata tcttcaacga catcgacgtg ctcgcatccg ccgtagtagc 3655861 gtttgcccgg atatccttct gcgtacttat ttgtcaaaac agatccttgt gcttccataa 3655921 ccgcttcact tacaaagttc tcagaagcaa tcaattcgat cttagtctgt tggcgttcac 3655981 gctcattttt aatggcgtta aacacttgtt cgtcttgcgc aggtaaatgt ttcatcagcg 3656041 agatcctctc ctatccgtat cctgttcttt gtttttacca tcactattgt acatggtttt 3656101 taaggccgat gtaaaagatt atttttaaaa aatctaaatt tttattggta aaaacgaata 3656161 ttaataactt aaatttaatt taaagttcgg aatttatttc actatcttaa aataaaagaa 3656221 aagactggct atgcagtcct ttcattcgca ctcataaacc gcccgcactc cgccgattag 3656281 tttcggccgt gtacgcgcca atgtcacatg agctgaaccg aggctgtttt gagagacacg 3656341 cacagggaca gccaccggtt tcagatgcat gccgataaac gtatcgccta tatcaattcc 3656401 ggcgtcagcc tgaatggttt caacaagaac aggagacttc atctgcttaa acgcataaga 3656461 cgccatcgct ccgcccgctt ttggaacggg cacggcagaa acggttggaa gcctgaacag 3656521 cttggctgtt tctgcttcga cgacaagcgc tctgtttaaa tgctcgcagc attgaaacgc 3656581 cagatggatt cccgtttttt cccggagctc agcaagtccg ctgtagatgc tttcagcgat 3656641 atctacactg cccgatgtgc cgatccggct gccggccact tcgctcgtgc tgcatccaag 3656701 gacgaagagc tgatcttgtt tcaattccgc ttggtcctga aactcagaca gcatcgtctt 3656761 ccacgtttgt ttcaactcat tcattaaaca gcacccctac aggtttttct cttcataatc 3656821 ggagattttt ccaatacgcg tttggtgtct tcccccggta aactcagtag tcagccagat 3656881 ttttgcgatt tcccgagcca aaccaggtcc gatcacccgt tcacccatcg caaggatgtt 3656941 tgtgtcatta tgctccctcg tcgccttcgc gctgaaggta tcgtgcgcca gcgcgcagcg 3657001 aatccctttt actttattag cggaaatgct catgccgatg cctgtcccgc aaattaaaat 3657061 gcctctgtca acttcgccgc taaccacttt ttcggccacc ggaaaagcat aatccggata 3657121 atcgacagag ccgctgccgc agtcacagcc catatcaata tattcaattt gcaattcgtc 3657181 cattaactct ttgatttcat ttcgaatgtg aacgccgcca tgatccgatg caatggctac 3657241 tttcatctgc ttttcctccc agcgtgtgtg atgcggcccg cccgctttat tgaccgcgca 3657301 gcctgtccgc tctttgattc acaccatatg atgtgctttt cactatattc tactccttca 3657361 cgcaggattt gcaaatgacc tgtttgcaga ttttctgaca acttatctac ggtctttttt 3657421 cagctgtttt gccagctgcc gaagaagctc ttcaagctca tctcgcgttt gtttatagat 3657481 gtcaattgag ccgccgaacg gatcgaggac atcaccatgg ctgcctgtga catattcttt 3657541 taacgtaaac actttatcac gataacgtcc aaattggctg gcaatgatct gtttgtgctg 3657601 atgggtcata gccagaacca aatcagccga ttccataagt tcttcagtta atggagaaga 3657661 cacatgatta agggcaatgt gtttttcaaa cagcgcttcg actgcatgag gcgtcgcttt 3657721 cccattaggt gaagcaaaca cgcctgccga gcggacattg acattcagcc cttccctttc 3657781 tgcaattgat ttaaaaagcg cctcagccat tgggctgcgg cacgtatttc cagtacagac 3657841 aaaaataata tccatgtcag tcacccctta tttttctcta ttatatatga agaaaaaaga 3657901 aacggcgact tcgtttcttt tattggtata ttaaattggc aaaagcagct ttaatccaaa 3657961 cacgattaat atgatgcccc cgagcgcttc gctgtatgtg ccaagccatg actgcacttg 3658021 ttttccgacc agcaggccca gccatgtcaa catcatgctg aacagcccga acagggtaat 3658081 tgtgaggagc ggatgcgagc cgtatatccc caagctcaag ccgacggaaa agctgtcaag 3658141 gctgacgccg atggcaaaca gcaataagcc cggccctgcc ggtgacatga atcgttcttc 3658201 tgactgttta aaagaggcca taagcatttg aaccccaaga acaaaaagca gcgccccacc 3658261 gatataaacc gctaacacgc cgaggagccc tgacagcatg ttaccggccg ccatccctgc 3658321 gagaggcatg atgacgtgaa agaggccgat gatgaaacca atatagaata tctgcttctt 3658381 tctaagtttg accatgccca ttccaaggcc gacagaaaaa gcatccatcc ctaaagcaaa 3658441 cgccatgatg cttaatgtaa tcagttcgcc tataaacaaa tccgacatac ataaataacc 3658501 cccttggaca cgccccgctt ttttagccta tgcgtgtcca aaaagggtta gaacatctga 3658561 ctgctttcag cgaatcactc ttcctccggc ggctttcatc agcctgttca taatagcaag 3658621 accgacacct gtatccggaa aggattccgc tataatgaaa tccaccttat tctcatcaaa 3658681 gctgcgcaaa gcatcataca gccctgccgc aacagtctca agctgagccc gtcttccgca 3658741 gctcttcaca taatcagcgg aataaacgcc cgctttttct tctgtcgtca ggacaccgac 3658801 ccgtcttcca ccctgttgat attcttgaat gaggtgctga atgcgctctg ggctgccttc 3658861 gcaaatggca agaggcgctg tcggcgcata atgtgtatat ttcatccctg gagaaatcgg 3658921 cttctcgttt tggtcgctga gccctttatc cacatggatc ggcccgatca ccgcttcaat 3658981 ttgttccttc gtaatgccgc caggacgcaa gagaacaggg atgtcgtccg cacatgaaag 3659041 cacagttgat tcgaccccga ttccggtagg gcctccatcc acaataccgg ctatgcggcc 3659101 atccaagtcg tgagccacat gctccgcttt tgtgggactt ggcttgcctg atagattggc 3659161 gctcggtgct gcaatcggca gtcccgattc gcgaatcaat gcaagggcaa gcggatgatc 3659221 cggcattcta atggcaaccg tttcaagacc tgccgttaca cgaggtgaaa gcgcatcagg 3659281 tttgcaaggc agaatgagcg taagtgctcc cggccaaaac cgtttcatca atgttttcgc 3659341 cttttccggc gccgggcccg ttaaatcctc aagctggctg atatccgcaa tgtggacaat 3659401 caggggatta tcgctcggcc gccctttcgc ctcatatatt tttttgacgg catccgtatt 3659461 ttttgcgttt gcgcctaggc catatactgt ttctgtcgga aaggcaacga cctcattttc 3659521 tcggagcaaa gcggctgctt gtgcaatttg tggatcattt gtggataact cgtcagttac 3659581 atccacaaac catcttttcg ttttcatttc tgaccaaact ccttattcac aacaataaaa 3659641 cgattgtttt acgcgtgtaa tccttttgaa agtataaaag atgtcctgta ataaaacaag 3659701 cgttatccac aaattgtgga caacgctaat aaagaagtgg ataagtatgt gtataaactg 3659761 cacttatcca gacgcttttt tcatcaaaac ggctccttct gtttgccgcg attcacagaa 3659821 gtgatcagaa gaaaacagct cctccggtac actctcagct ctttcaaaac ccatggccgt 3659881 cagaaagtcc gcagaggaat gctgatttgc tactaggtac acggttttga tctgatgctt 3659941 ttcgcacagc acctccatgc tttgaaaaag cgtgacgatg tggccttggt gaagcttgtc 3660001 cgatatgaca agtgatcgca gcagcccctg gtcacagctt attttttcaa taccgaggca 3660061 tccggcaatg tttttctcac tgtcctccag cataagaaat tgagtgaagc cttctttcac 3660121 gccttcatag ctggtttttg cctgttttaa aaatgcctcg agcacatctc cgtctttttc 3660181 ccttgccacc cgcagttgat aaaacatccg ttcaccccgt ttttgcgttc tttcttccaa 3660241 tctatgaggc aaatctattt ttagaccaga tgattaggaa aaaaggtcgg aaatccattc 3660301 gactaaaaag aatttcactt ctgtgccgtc ttctttttct tcgttctctt cttttttggc 3660361 tttttccgct ttagcggtta cgtcctcaag cactttttca gtctgctttt ttgaggcttc 3660421 tttatcttct tgttctttga cggcttcccc gttagaaaaa tcaagaaagc agaggggcgg 3660481 gaacagcaca caccaccagt tggcgccgtc tccgtttcca agcgtaatca aaatcgcttc 3660541 atactcacca gcgggatata ccatgttgcc gtaaagcttt gtcggaaacg agattttgtc 3660601 aaaatcaacg gatatcgact gattcgctcc ttctttctcc attgtttcct ttgcaattgc 3660661 tttgatttca ggcagctttg aacgaatcac gcgacgcgct tcttcaatag aagtaatatc 3660721 ctttacccaa gttgtgattt ctttattcac cgcgtctctt atatgacgtt ttaattgctg 3660781 gtcttgatca ctatcgctgt ttgccagtat tctcaaacga atcgcctgat caggtatgac 3660841 caccggctga ttttccgatt tttgtgccgt ctcttctttt gccagcccta cgagcgctcc 3660901 ggataataaa agaaagatat atatacaaat gattactgtt tttttcatcg gtccccaccg 3660961 ttcctctccg tgctttgttt ctagccctat tatggacaag gagagcctgg gataaacgtg 3661021 cagggtgaaa aaaatctagc aagctgttaa tcttatttat ggtacgatag tgttttagga 3661081 ggtttaagat gaaatacaat tatacagtgc tgttatcagc attcacgatg tccgttcttt 3661141 attcagtaat ttatattcat tcatttatca ttgccgctct catcacaatg gcattttatt 3661201 ttctgtttcc ttatttgatc ttcgcactgc cgcttcaaat catgatgaat aaaaagccga 3661261 aacgtttcag ccctttgtat ctgctgtatt accttgccgc tgcttttatt gccaacgcga 3661321 tcattttcgg catgcttcag ccttcgggac aatctctgtt tcaaaataca gccttttatc 3661381 ttttcgctgt attaacagct cttatctatt ggatatggga ttctgtttta ctgcaaaaaa 3661441 aggaagccta agaggcttcc ttttttatta aaacaaaatc gtcagtaaat aacatagaat 3661501 ggaaggtatc gccgcaacaa agaaagcggc cgccattttc atgcgagatg tacggccttc 3661561 tttggtttct gaatggtagt ttgcccgctg atcgcttccg cttacagcca aacccgatgt 3661621 aatgatcgcg agccccacta aaacgagaga cgcaacgcca aaaatcgctt catatgaaag 3661681 agcctgcgga aaaatggtgc caatcatgct ctcaatcgca atgagcagga ttcctgctgt 3661741 cagggccttt ttcatgttta catccccttt gctggtgtta aacagcttga tccattcact 3661801 cgccagcaag ctgcttattt atttttatga atcagagcgc atatggttct gtcttttcca 3661861 ttaatatctt tcagcacttc cacttccgcc cccttaaacg ccttgaggat caggtctttg 3661921 accgccgctc cctgtttcca gccgatttca aaaacgacaa atactttatc cttcataaca 3661981 agcggaatgt cttccataaa ccgcttataa aatttcagcc cgtctccgcc atcggtgagt 3662041 gcgtgcagcg gctcatgaaa acggacaatt tccgataaat cagccatttc ttcctctgaa 3662101 atatatggcg ggtttgagac aatgatatcc gctttttttc ccgccttaat aaaaggctca 3662161 agcagatcgc cctgataaaa gcgcacattc gctccgagtt tttctgcatt ggcagaggcg 3662221 acttgcagcg cctctttcga aatatcgacc gccgacacag aaaagctttg gttttcaagc 3662281 gcaagcgtga cggctattgc gccgctccct gtaccaacgt caacaacttc gagcttgccg 3662341 tcttcagaaa aaacactccg atatttttca agcaaatgaa agacaacttc ttcagtttcc 3662401 ggccgcggga tcagcacatc atcattcacc ataaattccc gtccataaaa aaactctttt 3662461 cctataatgt attgaaccgg cacgccctct ttatgcatct caacgtgacg cttaaagcga 3662521 tacagttcgt cttcaccaat cggttcctgt aagcttgcga gcagcttgct tctctccatt 3662581 ccggtatcat aaagcaatag gagctcggcc gcattttctt ctcttcccgc ttcggttaaa 3662641 taagaagaag cccatttcag ggcttcgaat atcgtcttca tcttaacctt ccgactgctg 3662701 aagcttgctt gcctgatctt caacaatcag cgcttcaacc acttcgtcaa gttttccttc 3662761 aagaatctga tcaagctttt gaatcgtcaa accgattctg tgatccgtca cacggttttg 3662821 cgggaagttg tatgtgcgga tacgttcaga gcggtcacca gatccgactg ctgatttccg 3662881 tgtttgatca tattcagcct gggcttcctg ctgaaattta tcatagattc tggcacggag 3662941 aaccttcatt gctttttctt tgttcttaat ttgagatttt tcatcctggc atgatacaac 3663001 aacacctgtc ggcaagtgag tcagacgaac cgcagacatt gttgtgttaa cgctttgtcc 3663061 gcccggtccg cttgaagcaa atgtatcgac acggatatcc ttctcatgga tgtcgacctc 3663121 tacctcttct gcctcaggaa gacatgccac tgttgcagtg gatgtatgga tgcgtccgcc 3663181 tgattctgtt tccggaacac gctgtacgcg gtgggcgccg ttttcatatt tgagtttaga 3663241 atacgcgccg cttcctgtaa tcataaagat gatctctttg tagccgcccg ttccggttac 3663301 attcgcttcc atgacctctg ttttccagcc ctgaagctca gcataacggg aatacattct 3663361 gtacagattg cccgcgaata aagcggcttc ctcgcctccc gcagccccgc ggatctccat 3663421 gataacgttt ttgtcgtcat taggatcttt cgggatcagg agcaccttca gccgttctga 3663481 cagtgtttcc gtttccttct gaagttcaga aatctcttcc ttcaccatgt cgcgcatctc 3663541 agcatccagc ttctcttcaa gcatcgcttt tgcatcagcc agctgttctg acgcatctct 3663601 gtattgtcta tatacgtcaa ctgtttcttg tatatcagat tgctcttttg aatattctct 3663661 tagctttttc ggatcgttga ctacttctgg atcgctcaaa agctcattta atttctcgta 3663721 tcgttcttca attgatttta aacggtctaa cacggtcttc acctctgttt tcctgtgcgt 3663781 aacattctca ttatagtata gtgattaacc ccagtcaaaa gcatttcaat cccagctgga 3663841 aaagctccct ctgctatact ggaattcgag gagggatgat gttgctgaaa tccatacatc 3663901 atattgcaat catatgttca gattacgaaa agtcgaaagc tttctacgta cataagcttg 3663961 gttttcaggt gattcaagaa acgtaccgcg aagagcgcgg ctcctataag cttgatttgt 3664021 cgcttaacgg ctcgtatgtc attgagctgt tctcgtttcc cgatccgccc gaacgacaaa 3664081 cccggcctga agccgcaggc ctgcgccacc tcgcctttac agtcggcagc ttggataaag 3664141 ctgttcaaga gcttcatgaa aaaggaatcg aaacagagcc aatcagaaca gatccgctga 3664201 ccggcaagcg tttcaccttc ttttttgatc ctgaccagct tccattagaa ctgtatgaac 3664261 aataacagtt tttgaagaaa aaaaggagat acccactttc tttgccgaat cttttcttgt 3664321 tttgtctaac gggaagggaa ccgcattcta tggtcgaata cctagcttaa aaggaggtat 3664381 gggatcatga atacaaatat ggtagcaagt gaactcggcg tctccgcaaa gacggtgcag 3664441 cggtgggtga agcagctgaa tcttccggcc gaacgcaatg agctcggaca ctattcgttc 3664501 acggcagaag acgtgaaggt tctaaaatcc gttcaaaaac aaatctctga aggcacggcg 3664561 attcaggata ttcatctgcc gaaaagcgct aaaaagcgca caggcttcct tgtccaaaaa 3664621 acaagtagcg acacagaacg aagaatcgag cagcttgaac aaaagctgga caccctttta 3664681 cagcaaaggc aggacgaaag cgaattgatg gcaaggatgt cggaactgga acgccagctg 3664741 aaacaaaaag ccgatgaagg tgtatcttac cagctgcttc agcaccgcag agaaatcgat 3664801 gatattcttg cagatctgca atcactgacc tcacaaatga aagaattcac cgctcattcg 3664861 atccccgaga ctgctgctgc ttctgaaaaa accaaaacaa gaaaaaaacc gctgctgtca 3664921 ctgttcaaat ttcaaaccta aagcaaaaag ctcccttaaa gggagctttt tttgttacgc 3664981 agtaagcgcg ataatgattg gaagtgaaat caatgacaga atcgcactga ccacaaacgc 3665041 agttgcagtt tcttcttctt gtttctcgaa acgagtcgca atcatggctg caacggcaga 3665101 accagggaat gcaacaagaa ggattgcttt tgttgtttgg tcagctggaa gtccgatagc 3665161 aagagcaatc aggaacatta acgcaggctg aaccgcaact tttagtaacg caataccgat 3665221 agccggcata ctgagtttaa ttttacgaat accaacggta acaccaacag cgaagagagc 3665281 aacaccagat gttgtgcttc caagctgatc aagcatttta acacccagct caggaagagt 3665341 gaaattgaaa accagcacca agatcatact gattaacgga gcagctgcaa gcggctcaca 3665401 aagaccatgc aggattgatt ttcctgtcat cttccagaag ctgtcgccac tctcttcgtt 3665461 tttcttagaa gactcaccaa cagtagcgat aatgatcgcg agcggatcaa gaatcgcgtt 3665521 aaccacgata cctgtgaccg cgatcggaat cgcaacttca ttcgctccga ataagcttcc 3665581 caataccggg atacccataa atgcgaatgt cggctgtgca gagttcaaag aaaatacaga 3665641 tgagttcgtt aaatcatact tgaatataaa tctgcaaacc aaaagaatga tgatatagaa 3665701 accaacaatc ccaataatta aagaaatcat taaaggtact tgtgataaaa attcacttct 3665761 ggaagttgtc aaaataccag cgataaagtg agctggaagt gcgtatttcg ttactaacgt 3665821 acttacccct tttgccgact tggcatcata acttccaaaa tgtcctgcaa accaacccag 3665881 cacgataaca aagaagatcg gcgccaggag gattaagata tctaagatgc tcaaaatatt 3665941 ctcctccaaa tcctatgtcc gtatacttta gctttacaaa aagctttccc tcggacagaa 3666001 aaatttactc gctaattatt tcgcgatgac ttttttgtat tcaggtgtcc acattgcatc 3666061 aagtaccgct tgtttcacat cttcaggctg acgatttgcc acgccgtctt taattgctgc 3666121 ttcagcaacg gcaatcgcaa cttggataga aacctcttga agcttatcaa tgcttggaag 3666181 caatcctgct ccaggtgttt caagatcaac catttcagca atcgcatcag cagttgcagc 3666241 aaacatagca ggtgtaatga tacgcgcttc agctacaatt gaaccaagtc caagaccagg 3666301 gaacgcgaat gcgttgttag attgtccgat ttcataagaa acaccgttgt attctacatt 3666361 gtcaaatggg cttcctgttg caataagcac ttttccgtca gtccatttga acagatcttc 3666421 aggaacagct tcagcaaggt gagtcgggtt agacatcggc atgataaccg gacggtctac 3666481 gtgagatgcc atttctttta caatttcctc tgtgaatgca cctgaaaccc ctgaagtacc 3666541 aatcaagatt gttggtttcg cttgacgaac aacttcatcg aatggaattt gacctttttc 3666601 atcgcgcttc cagtctttca cttcatccgc attgcgaagg taaggttttt ggaaatcaag 3666661 gatgccttcg atgtcttcag tcagcaagcc tctgtaatca agtgtgtaga aacgtttgtt 3666721 agcttcttct tcagataatc cggctagcac cattgtgtca cggatttggt cagcaatacc 3666781 gataccagca gaaccagcac cgaagataac aacacgctga tctttaatag aagcgccggt 3666841 tttcttcata gcggcaagca cacctgcaag tgtaatcgcg ccagtacctt gaatatcatc 3666901 attaaatgtc aggatttcat gattgtattt tttcatgatg ttgcgtgcat ttttgttgcc 3666961 aaggtcttcc cagtgaagaa gcgctttagg gaagaatttc aatgcagctt ttacataagc 3667021 gtcaatgaaa gcttcgtagc gttcaccttg aacacgttca tgcttgttac caatatataa 3667081 aggatcgttt agaagttttt cgttgttcgt accgacatca agcacaaccg ggataacacg 3667141 gctagggtca ataccagctg cagcagtgta gacagccaat ttaccgattg caatattaat 3667201 accgcctaca ccccagtcac cgataccgag aatgctttcg gagtcagtag caacgataag 3667261 atcaatatcg cctgctgtcg catgaaggtt ttcaaacgct ttttcaatac cgtcaatgtt 3667321 atcgattgac aagtagattc cttgaggtct tctatattca tggctgtatt cctgaatcgc 3667381 ttcaccaact gttggcgtgt acacaacagg aagcatttcg cgaagatggt ttttcagcaa 3667441 tttatagaaa agaacttcgt tacggtttgc aagatcactt aagtaaacat tttgacgaag 3667501 gcggtcaggc tgcgcttgga attgctcgta cgcgcgttgt gcttgttgat caagagaaag 3667561 tacagttggc ggcagaagcc cttctaagcc gagttcttgt ctttcttcta gtgaaaaagc 3667621 aacgccttta tttaaagtag gaatagataa aacttctttt cctctaagag ttgtttctaa 3667681 gtggccttct ttcgtttttt ttatgttatt caagcaaatc tccttctttc ttgaaatagt 3667741 taaccaagtt aagtaataac ccatctaaaa tatgaccgat catgatcttt atgcgacttt 3667801 gtgacaatta ttcgaacaat gtctcaaaac tatttacatt acgtaagcta ttgtatgcct 3667861 gtcaaaatca aaattcaaga gaagaaaatt acttaatttt ttaatatact tatttaaatt 3667921 ttttaattga atattatcag aatataaaaa aaacaccggt gtttttagcc ggtgcattct 3667981 atctttatac ccatgttttg gactattttt tagatttacc tgggacttcg tgatgatgtc 3668041 tgcatcttgc ttcatatgat tcagctgcac caaccaaaat gaccggatca tcgtaagaag 3668101 caggtttgcc gtcaatgagg cgctgtgttc tgctcgccgg tgatccgcaa acagaacaga 3668161 cggcttgcag ctttgtcaca ctttccgcaa tcgccatgat attcgggacg acaccgaacg 3668221 gctctcccct aaaatccata tcaaggcctg ctgctatcac acggtagcct ttatcggcaa 3668281 gagatgataa aacctcaaca atttcctgat caaaaaactg cacttcatca accgcaacca 3668341 catctgtact ttcactgatg tgatcccaaa tgtccgcagc agacgaaatg gcatagctcg 3668401 tcatcgatgt tccattatgg gagacaacag cagcttcgct gtatcggtta tcaattacag 3668461 gcttaaatac cctgacttcc tgcttggcat aagttgctct cttcactctt ctgatcagct 3668521 cttcagattt ccccgagaac atgctgccgc aaatcagctc aagccacccg ctttgtttca 3668581 ttatgtacat aggcttcgct cccctctctc tgccagctgt gttttagaca atataaaaaa 3668641 caggcaagac tgctgcttgc ctgttgagaa atctattatt acttaagacc gtattttttg 3668701 ttaaagcgat caacacgacc atcagcagaa gcgaattttt gacggccagt gtagaatggg 3668761 tggcattcag agcaaatctc aacgcgtacc tcttctttta ctgagcctgt ttcaaattca 3668821 tttccgcaag cgcatttaac tgttgctttt ttgaaattag gatgaattcc tgctttcatt 3668881 gtatccatct ccttccgccc tgaatcccgt gtggaaacag agttattatt tcggagcatt 3668941 gtccgaaacg catatgagaa aattatatca gtgatttact tcttttgcaa atacaattta 3669001 ccttcttgca gatgatagat ttgcctgttt ccattcttga ttgagaatat cgaaaaattc 3669061 ctggtttgtt ttggtttttt tcatttttct catgaacttt tctgcgaaat caggtgaatc 3669121 agacatcgtt ttgcggatag accataaacg atcaagatgc tctttaggca caagcagctc 3669181 ttctttgcgc gttcctgaac ggcggatatc gatggcaggg aagatgcggc gctcggcaag 3669241 agagcggtca agatggagct ccatgttgcc tgttcccttg aattcttcat aaatgacatc 3669301 atccatacgt gaacctgtat cgaccagagc cgtagcaagg atggttaagc tgccgccctc 3669361 ttcgatattt ctcgcagccc caaagaagcg tttcggacgg tggaacgccg ctgggtcaat 3669421 ccccccggaa agcgttcttc cacttggcgg aatcactaag ttgtaggcgc gggcaagacg 3669481 tgtgatgctg tccatcagga taatgacgtc ttttttgtgt tccacgagac gcatcgcacg 3669541 ttcaagcaca agctcggcca ctttgatatg gttttccggc acttcatcaa acgttgagct 3669601 gacgacatcc ccagctacag agcgctcgat atcggttact tcctcaggtc tttcgtcaat 3669661 taaaagcacg atcagctctg cttcaggctg gttcgctgta atgctgttgg caatttcctt 3669721 cagcaacatc gtttttccgg ctttcggcgg cgcaacaatc aatccgcgct gcccaaatcc 3669781 aaccggcgcc atcatgtcca taattcttgt agacaagaag ttcggctttg tttcaagcac 3669841 catttgacga tccggataaa gtggcgtaag agccgggaaa tgcacacgct cttttgcaga 3669901 ttcgggatca tccccattta ctgcttcaac gtgcaaaagt ccatagtaac gctcattttc 3669961 ttttggcggg cgaaccttgc cagatacttt gtctccgttc cgcaaatcga aacggcggat 3670021 ttgtgaagct gagatgtaaa tgtcttctga gcttggagag tagttgatcg gtctcaggaa 3670081 tccgaaacct tcagactgga tgatctcgag aacgccttcc ataaacagca gatcttcctg 3670141 ttctgcattc gctttcagaa tggcgaaaat gagttctttt tttgtcagtt tgctgtaata 3670201 ggagatttta taatgtcttg caagttcata aagctctttc aatttcatat tttccaaaga 3670261 ggaaatagat acgtctttca taaaaacacc acgcttttca tagtcaatat cttactctga 3670321 acatgtcatc tgctgctttt gcacaacatc cgccaaagca cattcttttt ttaacataaa 3670381 ggaacttcta tcggtaacac ttccacccat gatcggcgct tttgttaaaa ggattgtctt 3670441 aatgagtttt gaaggaagcg aggacaaaaa catgagaaga tcaatactta tatcgtctgt 3670501 atgcggtaga aattgaaact ttcctagtgc ttaaaagaag gtattacgca gtaaaattcg 3670561 cagcactctt tatttttacc ttatttcaaa aaattattca actgaaataa ggttttgaca 3670621 cggaattgat agagttgacg cttttctgca aaagttaaag cgggctcaca cccgcttttt 3670681 ctgtttgtta tggacggatt acaagatttg gtttcttttt caagctgtgt ctgccgtcaa 3670741 cgaaacgaac agtgcccgat tttgcacgga taactaagct ttcagttgta ccgacagagc 3670801 ctttgaattg aactcctttt aacagctcgc cgtcagtaac ccctgtagct gcaaaaatcg 3670861 cgtcatcacc cttcacaagg tcttccatgc gaagcacttt gcttaaatca aggcccattt 3670921 tgtgacagcg agtgatttct tcttcgcttt gcggaagaag tttaccaatg atttctccgc 3670981 cgagtgcttt tagcgcaaca gcggaaagca caccctcagg agcgccgcct gatccgaaca 3671041 ggatatcaac gcccgtgtgg tcgaaagccg tgttgatggc gcctgcgaca tcgccgtcat 3671101 tgatcaattt gattctggcg ccggcctcac gaagctcgga aatgattttt gcgtgtcttt 3671161 cacggtttaa aattgtggca acgacgtcct caacgtcctt gtttttcgct tttgccaccg 3671221 ctttaaggtt gtcaatgaca ggtgcttcga tgtcaatgca gcccaccgct tccggaccga 3671281 ctgcgatttt ttgcatatac atgtcaggag cattcagaag cgtgccatgg tctgcgaccg 3671341 cgataaccgt cagcgcgttc cagccgccgc ttgctaagat gtttgtgcct tcaagagggt 3671401 caactgcgac atcaacgcga gggccgtacc cgtttccgag tttttccccg atatacagca 3671461 ttggcgcttc gtccatttcc ccttcaccga ttacaacggt ccctttcatc ggcactgtat 3671521 caaaaacgtc tctcattgca cttgttgccg cttcatcagc ctcatctttt tttccccggc 3671581 ccatccatct tgctgatgcc aatgccgcag cttctgtcac acgtaccaat tccattgata 3671641 aacttctttc catttcaaca cgatctcctc tcacaagaaa ccattatgaa ttttgaagct 3671701 gttctatttc ttcgtcagtc attctttcac gccaaattgt cgctccaagc ccctcaagct 3671761 tcttctcaag gctgctgtat cctcggtcaa tatgctccag tcccgtaatt tccgtgacgc 3671821 catcagccat cagtccggct accaccaagc aggctccggc acgcagatca ctcgccttca 3671881 cttttgcgcc ttgaagctcg acaggacctg tgatgatggc agatctgcct tctactttca 3671941 tattggcacc cattcgtctc agctcatcaa tgtgcttgaa tcttgccgag tagatggtgt 3672001 ctgtgacgac actcgtccct ttcgcccttg tcaggagcgc cgtcatcggc tgctgtaaat 3672061 cagtcggaaa ccccgggtat acgagggttt tgacgtcaac cggctttaag ttcttctgcc 3672121 cgccgacaat gaggagctgg tcgtcgcttg tttcgatatg atagcccatt tctctcagct 3672181 ttgccgttaa cgactcaaga tgagtaggga tgacgttatc gataatgact tccttgccca 3672241 ttgcagcccc tgcaatcata aatgtcccgg cttcaattct gtccggaatg atcgtatgct 3672301 tgcagccgtg cagttccttc acgccgtcga ttcgaatcac attggtgccc gcacctttga 3672361 ttttggcgcc catgctggta agcaatgtcg cgacgtcaat gatctcaggc tccttggcag 3672421 cgttttcgat gatcgttttc ccttctgcca aaacagcggc gagcataatg ttaatcgttg 3672481 ccccaacgct tacgacatct aaataaatcc gtgcgcctct cagcctttca gctcgcaaat 3672541 aaatggcgcc ttgttcattg gttacttcag ctccgagtgc ttcaaagcct ttgatatgct 3672601 gatcaatcgg acggggccct aagtgacagc cgccaggcaa tccaatgacc gcctgcttga 3672661 agcggccgag catcgccccc attaaataat atgacgcgcg aagctttttt actttcccgt 3672721 taggaagcgg catgctgatc atcgacgtag ggtcaacaac catttcccca ttctcaaaat 3672781 gcacgttgcc gccgatttcc tttaacaggt cacgcagcgt ttcaatatct gaaatctctg 3672841 gaagcccttc aattgtcacc tcggaatttg ccaaaatggt tgcaggtatt aacgcaacag 3672901 cgctgttttt agcgccgctg atatgtactg taccgtttaa cgagtcaccg ccggcaatat 3672961 tcaacttttc catgatagtc tccttccata agaagatagc tgcggagcta aataaaatgt 3673021 cattttattc tgtctctgca aataaagctc atgtccaaaa tctagccaat tcgaagagaa 3673081 agaatacaac acattgtaaa atatcaggaa gaaaatagcg aagctttggg gggtacaggt 3673141 ttcaaaagat gcacagagac ccgccggctc gagagacatc gtcgtcatcc ggcaaaagca 3673201 gtacgcatac ccttcattcc gatatcagct tctgcagccc aatgattcct tctctgtaaa 3673261 gcggcgtcag catctgaaga tccgctgtat caggtcggtg aaatacaaag gccgcggcaa 3673321 acaggcataa agctgtttgc cgcccctttc attatttgtt ccagtctgcc aggaattgtt 3673381 cgattccttt gtctgttaac gggtgtttag tgagcgcatg aatgactttc agcggcattg 3673441 tgccgatatg agcccctcta agagcagctt ctgtcacgtg ctgcggatgg cggattgacg 3673501 ctgcaatgat ttgcgtgtca aggccgtgaa tgtcaaaaat ctgtttaact tctgaaatca 3673561 ggtcaagccc gttgtggccg atgtcatcta aacgtcccag gaatggagat acatatgttg 3673621 cccccgctct ggcagcaaga agcgcctggt tggcattgaa gatcaatgta acgtttgttt 3673681 tgatgcctaa gtcagtaagt gctcttaccg cttttaaacc gtcagacgtc attgggattt 3673741 tcaccgtaat gttcggagcg atcttcgcca gttcttttcc ttcctcgatc atttcctcag 3673801 ctttcaaaga aataacctct gcgcttacag accctttcac gacgtctgtg atctcgcgaa 3673861 gacggtcgtg gaatgatacg ttagcttcct ttgctactaa actaggattc gtcgttacac 3673921 cggcgagaat tcctaattca ttcgcttctc taatttcatc gatattggct gtatcaacaa 3673981 agaataacat tttcaaaaag cctccctgat taagaaattt tctgaactgc gaatatgatt 3674041 gcgctttcta aagatagacg gaaaaccgcc tgtcaagctg tcaggcggct ataaaaagtt 3674101 ccaattgaat taagcttggt ttgaagaacc aaattcacgc attttaccga taactgtttc 3674161 tttgatcgct tcacgagctg gtccaaggta tttacgtgga tcgtactcgt caggcttagc 3674221 tgccaatgtt tcgcgaacag cttttgcaga agaaatttgg ttttcagtat tcacgttgat 3674281 tttagctgta ccaagtgaaa ttgatttttt gatgtcagca gtcggaattc cagtaccgcc 3674341 gtgaagaact agcggaaggc cagttgattt tccgatctct tccatttctt tgaagccaag 3674401 gtttggctca cctttgtaag ggccgtgaac agaacctaat gcaggtgcaa ggcagtcgat 3674461 gccagtgcgc tcaacaagct cttggcactc tttaggatca gcgtagatta cgccttcagc 3674521 gataacgtca tcttcttgtc cgcctactgt tccaagctca gcttctacag atactccgtg 3674581 gaaatgagca agctcaacaa ctttagcagt tgttgctacg ttttcttcaa atggatggtg 3674641 agaagcgtcg atcattacag atgtgaaacc tgcatgaatc gctttcgcac aagattcaaa 3674701 gcttgaaccg tggtctaagt gaatcgcaac aggaactgtc actttgtact cttccataag 3674761 tgcttttacc atagcaacga ctgttttgaa gccgcccatg tagcgtcccg caccttcgga 3674821 aacaccaagg atcactggag atttttcttc ttcagctgct tgtaaaatcg cttgagtaaa 3674881 ctcaaggttg tttaagttaa attgtcctac agcgtaccct ttttctttag ctgtattcaa 3674941 catttccgtc atagaaacta aaggcatgtc gaatgtcctc cttatgtagc ctgattgtct 3675001 tctagcgaaa aaagctttcc accctagcat gacccatata ttgctgtcat atgtaaatac 3675061 tcagatcgct ttttctccat aactaggata ccaacttttc gacaaatcgg caacataatg 3675121 acatgattca tttgtttctt ctttttgtca gttagacttc aggggcagat attttttgac 3675181 ggcgtctctg atttcgtcga tgtcaaacgg cttggcaaag tgcgtcagag cgcccaattc 3675241 cttcgattcc tggatcatgt cgagctctcc gtatgccgtc atgataatga cccggatgtt 3675301 ttcgtcaatg accttcatcc gttttaagat ttcgattccg tccatgccgg gaattttcat 3675361 gtccaacagc acaaggtcgg gccgttcttt tgtcacaatg tcaagcgcct gcaggccgtt 3675421 cgcagcctga aacgtctggt agccttcttt attgaacact tcatttagca aaatacgaat 3675481 gccgtattga tcatcaacga ttaaaatttt ttcattcatc attttacacc ccaatattat 3675541 gattttcgtc aaaagtaagc agtattgtat gtattctgtt tgattttcct atttccttta 3675601 attataatag tctactttac gacattttct gagcattttc tcttttgttg tatactgata 3675661 ttgtacgtta taaaggagga ttcacttatg ttgaaaatat tcacgacgca gttaacaggt 3675721 attttttccc gcattcagga taaggaatct gacgcgattg aagatggggc gcggctgctt 3675781 gctcaagcgg tgatcagcgg gcattccatt tatttatacg gagcgaatga gcttcagggc 3675841 gtcttttatg aggccaccga aagcaaagaa cccttcccat ctgtcaaagc ctttccagaa 3675901 aacgctgagg aagtgacaga aagcgacagg gtgctgatgt tttgctcagg gacgggcaca 3675961 gccgaagaac aggagctcgc aaaagagctt tatgaaaaag gtgcgggagt cgtatgcgta 3676021 tcgcccgcag ccaaagacag tgcgggaata gaacagtatt gtgatgtgca tattgattct 3676081 aaattaaaaa tgccgcttgt tcccgatgaa gacggcaccc gttacgggtt tccctcttta 3676141 atgacagcac tgtatgtcta tcacgcttta tcgtttacac taaaagaaat tctgcaagag 3676201 tatgcataat atcttattgt acatgctgga acttgccgga aacaaataaa aaagacttgc 3676261 ccgcttttga caaacggcaa gtctttttta ttacttctga tttgcagctt cgacagacgc 3676321 tccgataaag cctttgaata gaggctgagg tcttgtcggt cttgacttga actctgggtg 3676381 gaactgagaa gccacgaacc aagggtggtc tttcagctcg atgatttcaa caaggcgtcc 3676441 atcagggctt gtgcctgaga atacgaagcc ttgctcttcc atttgctgtc tgaattcatt 3676501 gttaaactca tagcggtggc ggtggcgctc gtacaccact tcatcctgat acacttcaaa 3676561 ggctttcgtg ccttcttcaa gcttacaagg gtaaaggccg agacgaagcg ttcccccaag 3676621 atcctcaaca tccttttgtt caggaagaag atcaatgatc gggtattgag ttgacggatc 3676681 aatttccgct gagtgagcgc cttttaagcc caatacgttt cgtgcgtatt caatagacgc 3676741 cacctgcatg cccaagcaaa tgcccaagaa cggaatgttg ttttcgcgcg cgtattttgt 3676801 cgcgacgatt ttcccttcaa caccgcggtc tccgaatccg cccggcacaa tgatgccgtc 3676861 tgttccgctt gtgagttctg cgatattgtt ttctgtcact tcttccgcgt tgatccactt 3676921 cacttttaca tctgtgtcaa acgcatagcc cgcatggcgg agagactcga caacagaaat 3676981 gtatgcgtca ggaagctcaa cgtatttgcc gacaaggccg attgtaatcg tttgagacag 3677041 gttgctgact ttgttaacaa gctctttcca ctcggacatt tccgcttctt tgcatgccaa 3677101 tttcatgtgc tcgcaaacaa gcttatcaag cccttgtttt tgaagctcca gcggaatgga 3677161 gtaaaggttg tccgcatctt cacattcaat aaccgctttt gtatcgatgt cgcagaaaag 3677221 cgcgatttta tctttcatat cttgagaaat cggcatttct gtacgaacga cgatgatgtt 3677281 tggctgaatg cccaagctgc gcaattcttt tacgctgtgc tgtgtcggtt ttgtttttaa 3677341 ttcgccagca gctttaatgt aaggcacgag cgtacagtgg atgtacatta cgttttcacg 3677401 gccgatgtcg ctcttcattt ggcggatcgc ttcaaggaat ggcagtgatt cgatgtctcc 3677461 gacagtaccg ccgatttctg taatgacaac atctgcgttt gtctctttcc ctgcgcggta 3677521 aacacggtct ttcaattcgt ttgtgatgtg cggaatgacc tgtacggttc ctccaaggta 3677581 atctccgcgg cgttcttttt taagaactgt tgaatagatt ttacctgttg tcacgttgct 3677641 gaatttattc aggttaatgt cgataaaacg ctcatagtga ccaaggtcca agtctgtttc 3677701 agcgccgtca tccgttacga atacttcacc gtgctggtac gggctcattg ttcccgggtc 3677761 aacgttgatg tatggatcga atttttgaat cgtcacgttc agtccgcggt ttttcagcaa 3677821 acgccctaat gaagctgcta caataccctt tccaagtgag gatacaactc ccccggttac 3677881 aaaaatatat ttcgtcattt cgtttgctcc tctcttcgct cttagctaca tttttaaaat 3677941 gtactatttt ataaaaaatc atttagcctt ttaaatgatt tataagaaaa atgaggggtg 3678001 aaaataagaa agctcccttt caatttcttg aaagggagca taacgtacta tgttctctct 3678061 tcgtttttga agagcccaaa atacatacta catagttcga ctatgaaagt caagatcgtt 3678121 ttgaagatga aatctgatac tatttaattt cctcttcttc atcatcatag tcttcatcat 3678181 cttcatcaat aatatcttct tcgatctcaa gatcatcgtc gtcttcatca agatcttctt 3678241 cgtcaaaatc gtcggcttca agatcgagtt cttcctcaac ttcatccaaa tcaaggtcgt 3678301 cttcgtcgat ctcttcaaac tcgtcaagat caagatcttc ttcgactgct ttcttcgctt 3678361 ttttcttttt cgccttgact gtcggctgag tttcttcatc aagctgatca taaggatacc 3678421 agctgcgaag cccccacgtc tggtcagaaa gcgccaggaa gcggccgtca atgtttaaat 3678481 ctgtataaaa ttgagcaatg cggtctccaa gctcttcttt tttcacgccg agcaaagatg 3678541 cgatttcatt taaaagctcc tgaaaaggaa ctggtttttt atgttcttca aataattcgt 3678601 gagcgatttc aactaaagcc atttccttta gctcttcctg tgaatattgt ttgataccca 3678661 aggtcggaca ctccctttct attacttata tgtatctgtt ttatcaataa tgaaagcgat 3678721 tttgtatcgt tcttatacaa accatacctc tcattataaa caaaataaaa cagaatatgc 3678781 tacccttaac agcgttaatt taaataattt tacaagagtg atccgactga gagatgtttt 3678841 ccgttaatcc gcgagcattc tggagatgac cagtctttga atttcttgag tgccttcata 3678901 gatttgcgtg atttttgcat cacgcatata gcgttctacc ggataatctt ttgtatagcc 3678961 gtagccgccg aaaatctgca cggcttcggt cgttaccttc atcgccgtat ccccagccat 3679021 cagtttggac atggcggaag cttttccata tggaaggccc gatgattcta accatgcagc 3679081 ctgataggtc agtagccttg aagcttctat cattgtcgcc atatccgcga gtttaaaagc 3679141 gatgccctgc tgctcggcga tcgattttcc gaattgcttt cgctcttttg catattgaag 3679201 cgccgcatca agcgctcctt gggcgatgcc tacagcttgt gcagctatgc cgtttctgcc 3679261 tccgtcaagc gtcttcatcg cgattttgaa gccttctcct tcttctccga gacgctttga 3679321 tgcgggcact acacaatctt cgaacatgat ttccgttgtc ggtgaagaac ggatgcccag 3679381 cttcttttct ttcttgcctg taaaaaatcc ttcaaaatcc ttttctacta taaaagcggt 3679441 aacgcctttt ttctttttct cgggatcggt gacggcaaaa acaatgtaaa tatcagcaac 3679501 gccgccgttt gtgataaaca ctttggaacc atttaacaca tagtcatcgc cgattcgttc 3679561 agcagttgtt ttcatgctgc cggcgtcaga gccagaccct gcttcggtca aagcgaatgc 3679621 gccgattttc tctccgagag ccagctgtgt taagtactct gtcttctgtt cctctgtccc 3679681 aaaggcaaac agcggccagc tgcaaagaga gatatgggcg gaaagcgtca caccggtgga 3679741 ggcgcacact tttgacagct cttccaccgc gatgacgtag gctaaatagt cacttccaat 3679801 tccgccgtaa tcttcaggcc atggaattcc cgtcaggccc agatttgcca tttcccgaaa 3679861 cagctcgcga tcgaagcgtt cttgttcgtc ccgttcagcc gctgtcgggg ccacctcatg 3679921 cttcgcaaaa tcgcgcacca attttcgtat catctcatgt tcttctgata atgaaaaatt 3679981 cattgcttct cccccatttt cagatcagcg cctaaaacgg attgagccag aagctcgacg 3680041 acgtcgtacg ttttgacttg gtcttcggct tccttcgcct ttgtgccgtc cccaagcatc 3680101 gtgagacaat acggacagcc agaactgatc accgatgggt tgactgcgag cgcttgctct 3680161 gtcctggcga cgttaatcct gttgcctgtt tcttcctcca tccacattaa tcccccgccg 3680221 gctccgcagc acatgccggt ttcccggctt ctctccattt caacaagctg cacgcccgga 3680281 atggctttca aaatctctct cggcggatca tagacttcat tgtaccggcc caaatagcac 3680341 gaatcatgga aggtaatcgt ctcatgaagc gggtgctgcg gtcttaattt tccgtttttc 3680401 acaagctcgg ccagcacttc tgtatgatga taaacctcgc cttcaaatcc gaaatccgga 3680461 tattcgtttt taaataaatt gtatgcatgg ggatcgatcg taacgatttt tttgacatca 3680521 tttttttcaa attcagaaat attcttctca gccagctctt ggaacaaaaa ttcatttccg 3680581 aggcggcgcg gcgtgtctcc tgaatttttt tctttattgc cgagaatcgc gaaggacacg 3680641 cccgcgtgat tgagcagctt ggcaaaggaa attgcgattt tctggcttct gttgtcgtaa 3680701 gaccccatgg agcctaccca gaaaaggtac tcaaattctt ttccttcttt tttcatttct 3680761 tttacagtcg gaatctcagc atccggcgcc tcgtcacgcc aattttcacg ttccttgcgg 3680821 ttgagtcccc acggattccc ttgccgctca atacttgtca ttgcgcgctg ggcgtcactg 3680881 tccatttttc cttctgtcag tacgaggtag cggcggaggt cgatgatttt atccacgtgc 3680941 tcattcatga ccgggcattg atcctcacag ttccggcaag tggtgcatgc ccaaatttct 3681001 tcctctgtga tgacgtcgcc gatcaagctt ggattgtaat caagcgccgc tgcggcttcc 3681061 tgcgatccgc tgcccgctga cgccgcagcc agctgattgc ctctcgtatg ccgaaacgct 3681121 gctgcgggca cccatgggga gcgcgaggtg acggcagcgc ctttttccgt gagatggtct 3681181 ctgagacgca aaatcaagtc catcggagaa agcatttttc cggtgcctgt tgcaggacac 3681241 atattggtac agcggccgca ctcgacacac gcgtatagat caagcagctg agactgtctg 3681301 aaatcctcaa tttttcccgc tccgtagctt tctttcgttt cgtcggtaaa atcaattttt 3681361 tcaagttttc cggcagattc cattcgattg aaaaagacgt ttgccgggcc ggcgattaaa 3681421 tgggcatgct ttgactgagg cacgtacact aaaaagctaa gcaagaatag gagatggatc 3681481 caccatgcga tatagaaaat caccgccgcg cctgttttcc cgacaccgct aagcataaac 3681541 gcaatacctg aggcaattgg ctcgctccaa gaaagcccat gctcatgcca aatcagattc 3681601 atcccgttcc caagcagaac ggtcagcatt aatcctccga taaaaatgag aacgagtccg 3681661 gctttgaaac cgcgtttcag cctcacgagc ttttcgatat aacgtctgta gaatgcccac 3681721 ccaacagcaa ttaaaatgag aaacgtaaca atttcctgaa aaaaggtgaa ggcgggatag 3681781 accgggccaa gcgacagatt ccggccggga gccagtcctt tgatgataaa gtcaattgct 3681841 ccgaactgaa ccaatataaa tccgtagaaa aacatgacgt gaatgattcc gcttttcttg 3681901 tccttgagca gttttttctg tccgaataca ttcacccata tggcgtgaag ccgttccttg 3681961 aaccgttgat caaattgttc tttctggccg agcttgatgt aggccagtct cgttttgacc 3682021 aagtaaacaa acaaatagac agcgtaagcg gttacaatca gaaataataa tgcatttgcg 3682081 atgagaaagc cgctcattcc aattccccct ttttactgat aaagaccgcg atcccctacc 3682141 cccgaatctg tataagatta tctttatgat aaataatgaa tgagtgttca gtcaataatt 3682201 aaattcctgc tgttcgggca cactaccttt actacggaaa ggagtgccgg tatgaaggta 3682261 tttatcgtga ttatgatcat tgtcgttatt ttctttgcct tgattctgct tgatatcttc 3682321 atgggccgtg ccggatacag aaaaaaggcg tacgagcctg ttttttcaaa aaagaagagt 3682381 gacatcgaat tgatccactg cggcgctgat ctcgttgagc ggatgatgaa tgatattcgc 3682441 caggccgcct cttctgttca catgatgttt tttattatga aaaatgatga ggtcagccac 3682501 aatatgtata ccttgctgaa aacaaaagcc caagctggcg tatccgttta tttgcttctg 3682561 gattgggcgg gctgccgggc aattaaaaaa acggcgcttc agacgatgaa aaatgccggc 3682621 gtccatgtcc atgtgatgaa tcgtccccgt tttccttttt tcttttttca catgcaaaaa 3682681 cggaatcacc ggaagattac ggtgatagac ggaaaaatcg gttatatcgg cgggtttaat 3682741 atcgccgaag aatatcttgg aaagaaggcg aagttcggca attgggagga ttatcatctg 3682801 cgcatgatcg gagaaggcgt acatgatctt caaacgcttt ttgcttctga tctaaaacga 3682861 aataccggaa tcgaactggg ttcggatgtt tggccaaagc ttcagcaagg gactatttct 3682921 cacaagatct atgcgaccga cggttattcc cttgaaaaca tatacttggc caacattgcc 3682981 caagcgaaga atcgccttac ggtttgcacg ccttattaca ttccatcaaa accgcttcaa 3683041 gaggccctta ttaacgcaag aaaaaacggc gtatccgtga gaatcattgt accgatgaaa 3683101 tcagaccatc cgctggtacg agaagcggct tttacgtatt attcggagct cttggatgcc 3683161 ggctgtctta tttatcgtta ttatcaaggg ttttatcatg taaaagccct catcatagac 3683221 gaccatctca gcattatcgg aacagccaac ttcgataaac ggagcctgtt cttaaatgaa 3683281 gaggtgaatg ttgaaattga tgacgaagcg tttacaagtg aagtctatgc cacaattgag 3683341 gaggatatga aaaagtcgga gctgctgacg atggaggatt tcagcaagcg cacattcagg 3683401 cagcgcccgg cggaatggct cggcagggca ttatcttatt tcttataaag gagagttcct 3683461 atgattttca gattcgggtt cgtttcaaat gcgatgagcc tttgggatgc gtctcccgct 3683521 aaaacattga cattcgcgcg ttattcaaag ctttcaaaga ctgaaagaaa agaagcgctt 3683581 ctgactgtga caaaagccaa tttgcgcaat acgatgagaa cccttcacta tatcatcggc 3683641 cacggcattc ctttgtaccg tttttccagt tcgattgtgc cgctggctac gcatcccgac 3683701 gtgatgtggg attttgtaac accgtttcaa aaagagtttc gggagattgg agagcttgtt 3683761 aaaacccatc aactgcgaac aagctttcat ccaaatcaat tcactctgtt tacgagcccg 3683821 aaggaatccg tcacaaaaaa tgcggtaaca gatatggcgt atcactaccg catgcttgag 3683881 gccatgggca ttgctgatcg ctccgttatc aacattcata ttggcggcgc ttacggaaat 3683941 aaagacaccg ccactgcaca atttcatcaa aatataaaac agctgccgca ggagatcaaa 3684001 gagcggatga cacttgaaaa tgatgataaa acatatacaa cggaagaaac gcttcaggtc 3684061 tgtgagcagg aggatgttcc gtttgtcttt gactttcatc atttttacgc caatccagac 3684121 gatcacgccg acctgaatgt agcactgccc cgcatgatca aaacgtggga gcggatcggc 3684181 cttcagccaa aggttcactt gtcttcccca aaatcggagc aagcgatacg cagccacgcc 3684241 gattatgttg acgccaactt tttgctgcca ctgttggaac gctttaggca atggggaact 3684301 aatattgatt tcatgattga agcaaagcag aaagacaagg cgcttctccg cttgatggat 3684361 gaattaagct ccatccgcgg tgtcaaacgc atcgggggcg gtgcgctgca atggaagtca 3684421 taaatgtgca aaaataggtt tacgacttgt cagctttggg aacttaggct atataagaca 3684481 acaatcgatg gaggagaaag atcatgaaaa atatcaagtc tctgaaagta gccgcacagg 3684541 cctttacttt aagaaatttg attcatcttt ataaaatgtg ccattccgga agccacgagg 3684601 tttatattta ttcaaagaaa acgatgtgca aaatcaaaag cttaattgag cttgaaacgt 3684661 tccgcatggc tcataatgaa aaggaatatc tgatcgtagt tgaaggaaca aaagcatcac 3684721 agctcattga aaaattccaa aatctcatcg agcctgctga gagagaagcg ctctaactta 3684781 catacaaaaa aggatagaca tctgtctatc ctttttctta tgctcttaca taatggagct 3684841 gaaccgcttg tccaaattgt tttgtccctt ttaaccgcag ttttgtttca tttgttagtt 3684901 cgtgaaacag cgggatgccg cttcctaaaa cgacgggaat aacagtgatg atgaattcgt 3684961 cgatggcatc ttctttcata aagtcattca caagctctgc cccgccagct atccagatgt 3685021 ttgagccttt ttcctgtttc aaacgggcag tgaaggctct ggctccctca ttgataaacg 3685081 tcacatgttc atcttgataa ctgtcgggcg atcctgtaaa aacatagcag gttttatcct 3685141 gatacgggaa aaccggtgtt agcactttaa cgtgctcata tgtgctccgc cctaaaatga 3685201 ctgtatcaac agtctgataa aaatcactgt agccgttgtc accttcacct tcaaattcat 3685261 ccagccaatc gatgcttcca tcttcttttg cgatcatccc gtccaatgaa acagcaatgt 3685321 acagcacagt ttttctttcc atgttctcct cctatcgatg caccatttgc ccgaattgcg 3685381 cttgatgcag cctgctgtat aggcctccgg cttcgatcag gtcttgatga cggccttgtt 3685441 cttcaatacc gttgtttgtg acgactacaa ttctgtccgc gtctttgatt gttgccagcc 3685501 tgtgggcgat gacaagcgtc gtgcgcccct cagacaactc ttgaagcgcc ttttggatcg 3685561 ccgcttccgt ctctgtatca agggctgagg tggcttcgtc gagaatcaag atcgacggat 3685621 ttttcaagaa catccttgca attgacagac gctgtttttg cccgccggaa agcttcacgc 3685681 cgcgttcgcc aatcatagta tccaacccat cgggcatgtt atggacgagc tcttccagat 3685741 gcgcctgctt cacagcttgc caaatgtctt cttctgatgc gcctagtcgg ccgtaggcga 3685801 tattttctct aagcgtgccc gagaataaga aaacgtcctg ctgcacgacg ccaatctgcc 3685861 cgcgcaacga agaaagcgtc atgtctttta tactgatgcc gtcaatcgta atgtcgccct 3685921 ccgatgcttc ataaaaacgc ggaagcagac tgcaaagcgt tgatttccca gcacctgacg 3685981 gaccgacgaa cgccaccgtt tcccccgctt gaatggatag gttgatgtca ttgaggacat 3686041 tgtgatggtc atcatagcca aacgaaacat gtttatagcg gatattgccc ttcaggccgg 3686101 aaacatcttt cgaatcaggt gagtcctgaa tatccggctc tgtctccatg agctccatat 3686161 agcttttgaa acccgcgatc cccctcggat acatttcgat aatggcatta attttgtcaa 3686221 taggcctgaa cagcacattc gtcaagagta caaacgccac aaattccccg tacgataagg 3686281 agccgcgaat gacaaaccac gtcccgcaca aaaggacaaa cagcgtgaca aaccgggtca 3686341 gcatatagct gattgaaccg tttttcgcca tgattttgta ggaagaaagc tttgtgacac 3686401 gaaaacgctg gttgttgacg gcgaagcgtt ctttttcaaa tgcttcattt ccgaacgcct 3686461 gcacaagccg gatgccgccg atgttatttt ctacacgcgc gctgaagtct ccgatatcct 3686521 tgttcagcgt ggtaaatgct ttggtcattt ttttgttgaa ataaagcgct agccaaatga 3686581 cgatcggcat aatgataaac gttaataaag caagctgcca gttaataaac agcatcactc 3686641 cgaacgcccc gagaatggtc atgaccgcaa tgaataagtc ttccggtccg tgatgggcga 3686701 cttcaccgat atacattaaa tcgttcgtga gcttcgacat cagcgttccc gtcttgttgt 3686761 tgtcgtaaaa tttgaacgag agcttttgca aatggtcaaa aagcgacttt ctcatatcag 3686821 tctcaatatt gataccaagc atgtgtcccc agtaggtcac gatatactga agagccgagc 3686881 tgagcgcgta caccgcaaat aacccgattg aggtcgcgat gatcagtccc cagtccctgc 3686941 ccggcagcaa ggtatcaata aaataattga cgatcaaagg aaaactcagc tccattaaac 3687001 ctcccgcgat cgctgagaaa aagtcgagaa agaacaacgt tttatatggt ttataatatg 3687061 aaaaaaattg ccgcagcacc ctatcttccc ccaatgtata aataactgat aatatttctc 3687121 aattatacta tacacgggct gttttgtaag atcagatttc ttttttctta cagaacacct 3687181 gaaaacaggc gggcaaacga ctcttttgtc cggtcagcca cacctctttt ataaaagccg 3687241 acagggctga gcttttcact ttcctgcata tcctcttcaa aatgggcctc aagggttcgg 3687301 atcgcttcgg catccgtgaa gaacacattc acttcaaagt tgagctgaaa gctgcgcatg 3687361 tccatattcg cggtaccgac ggaggcgaga tcgccatcaa tgatcatgac tttttgatgc 3687421 atgaagcctt tttggtagga gtacacttca atgccctcaa ggagcagctc cgggaaatag 3687481 gacctcgacg cgtattgggt caaaaagctg tcgttcttct ccggcaccat aacccttacc 3687541 tctaccccct ttgtcgccgc tgcttttagc gccgtgcgaa tggattcatt ggggacaaaa 3687601 tagggcgtgg cgatccatat tgatttctgc gctgaagaaa tcatttcata ataaaggtcg 3687661 ctcatgcttt ccttcatgtc agggcctgtc gcgacaattt gataaatgcc tcctccttcc 3687721 acgggaaccg gggtattgta ctcctcttga tcaattagca cttcattgga gacatattcc 3687781 caatccagca taaagatagc gtggagcgtt tgcacaattt ccccctcaag ccgcaggtgt 3687841 gtatctctcc aaaatccgat gtacggatct ctgctgatat attccttccc gacatttaat 3687901 ccacccacaa aaccggtttt cccatcgatg atcacgattt tccggtgatt tctgaaattc 3687961 agcttctggt tgaaaaaccc gtatttcagc ggagaaaacg ggacgatgtc cacccccgct 3688021 tgtttcattc tcataatatc tcttcttgcc agcttcatgc ttcctgccgc atcgtataaa 3688081 aacctcacct cgacaccctg gcgcgctttc tccatcataa tatccatcat gccgcgtccg 3688141 agcatgtctg atttaaacat gtagtattca atatgtatgt aagattccgc ttttctcatt 3688201 gctttgaaaa tgtccgggaa ggtttcttcg ccgtttttca gcactttgat gttgcttttc 3688261 gtattgatat tcatatgggc agccctgatg gaatatgtaa agaacctctc ttgattgtcc 3688321 ttcagccctg tcacttcggg cgtttcctcc ttgtcaaaca gcttcctgag cttttccctg 3688381 ttgtacattc gttttgtctt aaacagcttt ccctttacat aaagctgtcc cgaaaacaga 3688441 taaaacacgt agccgacgat tggaaaaaag acaagaatat ggatccatag cagcgtgtgc 3688501 tgcgaggtgc ggttttcaag aattaatgaa tagatgctga acaaaataat gcttatatag 3688561 caaagcaatc ctccgtaaaa ctcaagtctg gaaaccggaa aaaaccaaat gacatatgcc 3688621 ccgatgagca tcatatataa aaagaaaaat tccagtctcc ttttcagcat cctgattctc 3688681 tccaatctga ttcaattacc tctgtattac ctcttttttc taatcgataa accttgtaag 3688741 taaaaaacct ctccgccaaa ggaggagagg tttagagaaa actaactgtc acggaattca 3688801 tccgcatcgt ttctgcagaa ataaagcaag actattggca acgccgagtg acaacatgag 3688861 cggcaagctg aacccgctca gcactccggc aagcgccgaa aagaaggcgg cgctgtgact 3688921 gcaaatacgg tggatagagt aaatttgata cccattctga tgagagaaaa tatataaaac 3688981 gggaaattga tcagaaagat ataaggagtt agtcaggctg aatcataatc tggctgttcc 3689041 gccggtttaa aatgagtaaa atccttgatg ttatttccat atacaaacat aacaggattc 3689101 ccggcagccc agccattacc ttggcagaaa aaaccccctc ttgcaagggg gattttcacg 3689161 agcgtttccg atatacaacg tagctgcggg tcagatactt gagcggcaga ctgaacacat 3689221 gaaccaatct cgtaaacggc cacaggataa aaacgacgta tcctatcaca atatgaaact 3689281 taaaccatag cgggacactc tccatcaaag aggcgtcagg cctgaacaaa acgatttccc 3689341 tgaaccaggg cccgactgtg gtccggtaat caaatccttt cgaatcaatg ttgagaaacg 3689401 tggccgcaac gcctgacagc atcatgaaca gcagcaggag gagcgtaagg atatcggatg 3689461 gcgagctcgt tttgcggatt cttttgtcaa acagccttct gtacgtcagg atgacaagtc 3689521 cggtacatgc cgcaatgccc gccggcaagc cagcgccaat cgccattttg tgatacatat 3689581 gctctgaaat gccaagggaa gcatacacgc cttctgggat cagaatcccc atgacatgcc 3689641 cgccgacaac gcacagcagt ccccagtgaa aaagtgtgct gccagccgca agttttttct 3689701 tttctaacag ctcgcttgat ttcgccgtcc agccaaattg gtcatgctga tagcggtaaa 3689761 tatggccgcc gataaagatt gtcaatacaa tgtatggcat aataccccag aggatctgcc 3689821 cgctcatgcc tgaacagccc cttcaacgct ttcacgtacg ccaatgtttt caagcgcggc 3689881 cagcagcacg tgcagcagtt cagcgtatat actgtcattt ttttcgagac gggatgccag 3689941 ctccctcaca ttggacagat atttctcaaa cacgcttctc gctgcttcaa tttctgcagc 3690001 cgcagcaaat tccagcatca gcggcagata atcaggcagc tctttctctg tcggcaggaa 3690061 accggattgc tcgtatgtgt tttttaaatg cagcaattca atgccgcgtt ccctttgctc 3690121 gcctgagtta aagtaggtga catacatatt tgtttttttc ccgaagtcga atgtatagac 3690181 atagtgttca atcagcgctt ccggagaata gctggctgac gtctcgaaaa agtgcagcag 3690241 cttctcccgg atttgccggt tgccgatttc ttggataaga gccttccaat cgggaagctc 3690301 ggctctccac tcttcatccg gataagagag aagacaggaa agagcagaga acgtgatttg 3690361 ccggtctgtg gtgttcatct tgttacacct catttatcaa aagttagaaa caggagccgg 3690421 ggccgcctga aaatgataag ccgcagcttc cttgttcagc gtataaatct gatacttctt 3690481 ctcgatggct gctcggaatc acaaagcggt catcatattt ggcaatcgca agcagccgat 3690541 acatatcttc aatttgctgt tctgttaagc cgacactgga gatcagttcc ggatcgattg 3690601 atttattcgt ctggaccgct ctcatatact ggcgcatgac agacattttc tttaatgttg 3690661 accgaatatg atccgtatca ccggctgtta acagctgcgc caaataatct atcgggattc 3690721 tcatttggtc gatagccgga aaaatatctt ccgccgtttg ccggctgcct tttccttcaa 3690781 agagattcat aatcgggctg agcggcggaa tgtaccacac cattggcagc gtgcggtact 3690841 caggatgaag cggcagcgcg atcttccagt caatgatcat tttatagatc ggtgattgct 3690901 gcgcggcctc tatccattca gccggaatgc cttgttcttt tgccagtttg gcaacctcag 3690961 gatcattcgg atcaagaaaa acgtccaatt gggaatggta gagatccttt tcattttcaa 3691021 cagatgccgc ttcctccact ttgtccgcgt catatagcat gacgccgagg tagcggattc 3691081 tgccaacaca cgtctcagag cagatggttg gcagtcccgc ctccaaacgc ggaaagcaga 3691141 gtgtgcattt ttccgctttg ttcgtttgcc agttaaaata gactttttta taaggacagg 3691201 atgagacgca atatctccat gaacggcatg cgttttgatc cacaagcaca atgccgtcct 3691261 cctcgcgttt gtacatggcg ccggatggac aggatgagac gcatgccggg ttgatgcagt 3691321 gctcgcaaat acggggcaaa tacatcataa agacgtcatc gaattctgtt ttgatcgatt 3691381 cctccatctt ttgtacgttg ggatcttcaa gtcccgtaat gtggccgcct gcgagatcgt 3691441 cctcccagtt cggtccccat tcgatattca tgaaatcccc cgtcaaggac gatttcgggc 3691501 gtgctaccgg ctggtgtttt ttctgcgggc tgttcgttaa tgtttcataa tcatagttcc 3691561 aaggttcata gtaatcatca attgacggct gattcggatt atagaaaagg cctgcaagcc 3691621 gattggtttt cgagcccgat ttcagctcga gctttccttt tttcaatgtc cagccgcctt 3691681 tatatttgtc ctggtcctcc cattgcttcg ggtagccgat gcccggcttt gtttctacat 3691741 tattgaagta catatattcc gcaccggaac ggtttgtcca cgtgtttttg caggtgacgc 3691801 tgcacgtgtg gcagccgatg catttatcca agttcatgac cataccgatt tgcgctttaa 3691861 tcttcaagcc aatcgacctc cttcagcttg cggatgacga cgttcaggtc gcgctgattc 3691921 cccgttggac cgtaataatt aaagccgtag ctgagctggg cgtagccacc gatcatctgt 3691981 gtcggcttga cgtgaatcct tgtcgggctg ttatgggtgc ctccgcggtt attcgtcagc 3692041 tttgtgccgg gcacgttgat gtggcggtcc tgggcatggt gcataaacgc cattccttta 3692101 ggaatccgat gagacaaaac ggctctcgcg acgacaacgc cgtttcggtt gaagcattca 3692161 atccaatcgt tgtctttgat atccgtgtcc tctgcatcat ctttattcat ccacacggtc 3692221 ggcccgccgc ggaacagcgt cagcatcggc agagaatcaa aatacatgct gtggacagac 3692281 catttattat gcggcgtcaa ataattgagg acgatttctt ttccctcttg atcaggccgt 3692341 ttgctcagaa acgggcgatg ctggaggatc ggtttgaatg tcgccatcgt ttcaccgaat 3692401 tccatcatca gttcatgatc gacataatag gattgtctgc ctgtcagcgt ccgccacgga 3692461 attaattttt caacattcgt tgtaaacggc gaatacctgc gccctccttt ttcagagccg 3692521 gtaaacgctg gagacgtgat caccgttttc ggctgggctg taatttgttc gaacgtaaag 3692581 cattcttcct cgcgttcttc cgccaggtct ttcagcttca ggttcgtgat gttttcaagt 3692641 gattcccatg cttttactgc gacctttcca ttcgaagtgg atgatagggt taaaatcgct 3692701 tctgcagcct gctttgcttc acttatattt ggacatccct ttgccacgct gtccgaggtg 3692761 atttctccca gtctctgttt gagtgattca tattcatcgg ctattgacca gctcatccct 3692821 tttgttccgc tcggctttaa agcaacgttc ggaccaagtg cagtcatttt atgaaaaatg 3692881 tgtttgtaat cccgttcaac gacttggatg ttcggcatcg tttttcccgg aatggcttca 3692941 cattcgcctt tgctccagtc attgattttg ccgaatggct gggccaattc ctgcatggtg 3693001 tcgtggagca gcggtgtcgc aaccacttct ttcaccggct ccatatcgac ttcttctgcc 3693061 agatcggaaa cggcttttga cagcgccttg aaaatatccc agtctgactt cgattcccac 3693121 ggagccgaga tcgcaggagc aaatggatga atgaacggat gcatatctgt gctgctgaga 3693181 tcgtgttttt cataccatgt cgccgccggc agcacgatat cggaatacag cgccgtaccc 3693241 gccattcgaa aatcaagatt gattaataag tcgagctttc cttccggcgc ctgctcccgc 3693301 catttgattt cttctgggcg gatgctgtcg ctgtcgtcat tcattaaacc gttcgttgtc 3693361 cccagcaaat gcttgagaaa atattcatgc ccttttcctg agcttgagat cagatttgcc 3693421 cgccatacaa agagattcct tgggaaattc acttcattgt caggatcttc aatcgcgaat 3693481 ttcagttttt tctcttggag ctgtgaggcc acgtacgcac ctacgtcttc aggtgttgct 3693541 gcccctgctt tttcagcttc tttatacaga tcgatgccat tttgattgaa agtcgggtaa 3693601 gacggaagcc accctagccg cgccgccagc acattgtaat cagcgtggtg cttgtagcgg 3693661 gatgaagcag caatcggtga tgccaaatca ctgatcggct ggtcctcata acgccactga 3693721 tctgtcgcaa agtagaaaaa tgaggtgcca ttttgcagct tgggcacgcc ttcccagtcc 3693781 tttgcagttg caatcgtctg ccacccttca gcaggtcgga gcttttcctg ccccacgtaa 3693841 tgggcccagc ctccgccgtt tacgccttgg gcgcctacaa gtaaaacaag atttaacact 3693901 gctcggtaga tcgtgtcgga gttgaaccag tggttaatgc cggcccctac gataatcatg 3693961 gaccggccgt ctgtatcgat cgcattttgg gcaaactctc tggcaatctt aacgacagct 3694021 tcttttttga ttcctgtcat ttgttcctgc caggcaggcg taaacggctc agggtcatca 3694081 taggagacag ccgatcgttc gccgatgccc cggttcacgc cgtagttagc cagtatcaag 3694141 tcaaacacgg tcgtgatgta cgtttcttca ccgttcaggt tcattttttt aataggaaga 3694201 tcccgctcga gcactttgtt tccgtcattt gaaaaatacg ggatgcgcac cgtgccgatt 3694261 tcgtcctcta ttcccagcac agagagacgg ggttcaatcg gttccccggt ttcttcatca 3694321 atcatgtgca ggttccattt ctgctgcccg tcccagcgcg agcccattgt cccttggggt 3694381 atggcaaatg aacttgtctg ttcatcccaa accgcaggct tccactgatc atgctttgtc 3694441 ttccgcccga tgtccttcgc atgcagaaac cgtcccgctg tgtatacgcc attttctttt 3694501 gacagagtga cgagaaatgg aaaatcagtg tattgcttcg cgtactcaat aaaacgttca 3694561 gtttcttggt tcacgtaaaa ttcctgcaga ataacgtgac ccatcgccat cgcaagcgcc 3694621 ccgtcagtcc cttggcgaat actcagccag tcatccgcga actttgagga ttccgcaaaa 3694681 tctggactga tcgaaatgac cttagcgcct ttatagcggg cctccgccaa aaaatgcgcg 3694741 tcaggcgttc tcgttaacgg aacgttggag ccccatgtga taatatagcc ggaattgtac 3694801 caatcactgc tttccggaac gtccgtctgg tcaccccaaa tttgcgggga tgctggagga 3694861 agatccgcat accagtcata aaaactgagc atagggcctc cgattaacga cataaaccgg 3694921 gagcctgatg cgtggctgat catggacatg gccggaatcg gagaaaaacc gacgtttcgg 3694981 tcaggcccgt atttcatcac tgtatacagc agagaggctg aaatcagctt cagcacctcc 3695041 ggccattcag cgcgcacaaa accgcctttc cctctcgcct gtttatagga cttcgctttt 3695101 tcagggtttt cgacgatcga tttccaggct tccaatggat tttgatgcgt ctgcaatgcc 3695161 tcccgccaca aattgatcag cacaccgcgc acgtatggat atttcacacg gagcgggctg 3695221 tagatatacc atgaaaaact ggccccccgc gggcagcctc tcggttcaaa atcaggcata 3695281 tccgggcctg ttgatggata attcaaattt tgcccttccc acgtgactat tccgtttttc 3695341 acataaatat tccagctgca agaccctgta cagttgacgc cgtgggtgga gcgaacgact 3695401 ttgtcgtact gccatctgtt tctgtataca ttctcccaat cgcgatcctc gcgggtagtt 3695461 tggctatgtt tatttgaatg gtgttcgata ggagagaaat aattcaatct cctaaacaac 3695521 ggactccttt tctttttctt catgagagtt cactccttcc gagtcaggtg atgctaagtt 3695581 cactataaac agagacagcg tgtttccttg tgaactatgt cacacactct gcttttttca 3695641 caaaatgttc acacaaagga gaaggaaggc tgcgttcagg caggacgctt gggtcattag 3695701 ctgcctttca ttcaaagatc aaaaaaaacc ggctctattt aagaaccggg ctcagcgttt 3695761 tcatcctgtg atgtatgcag ataccgcaaa aataattgat aggaacaaaa aacattttgc 3695821 tgaagcatag ccaaaaagtt catttgcagc tgcggatgat aagacatcat tttcttaaat 3695881 atgtaatatg ggatgttgag aatcagaatg tctgaagtgg cattgactga gataaagggc 3695941 gataaataaa gcccgccttt ttcatcaatc ggaaacacat cgcctttttc ccacagcgca 3696001 acggttttcg acccttcagg gagccttgtg tccataaaac ggacactgcc ttttaataca 3696061 atataaacag attgagaatg aagaaaagat ggagactgat cacatgaacc gcggataaac 3696121 gtgccgtttt tcagcaaggt ttcgacaatg gatagaggca cttcattaaa cataggaagt 3696181 tgtttcagaa ataataaata gtcacactga ttcataggaa aacctcctgt gctaaggata 3696241 gctttagtgt agctcgactg agcctgtaca gcagtgatgt atttcacagc ctgtatgatg 3696301 aatgtcactt atcaggaggg tgaatgcatt tataatgaaa gaaaaaagga ggatttcgat 3696361 gaaggcgctg attccgaagc agcacggggc gtgggcgatg ctgctgatcc catttttact 3696421 cggcatggtc aagggaggcc ccgttatttg gcatattccg ctcttccttg gttggctttt 3696481 cctatactta gcggtttatc ccgttacgct tgccttaaaa aagaaacaaa gcaaaccata 3696541 tcaaaagtgg atgtgttatt acggttttcc cacctgctgc tttttgatga tctcggtctt 3696601 tcataagccg cctctcatct gggtgggcgt ttctttactg ccgctgtttc tcatacatat 3696661 gtattttgcc cgcagaaaaa acgaacgagc cttattgaat gatgttgcag gtgtcttgtt 3696721 cttttgttcg ggcgggtttg cgagctgctg gctggggatg ggaacccttg acggctgggc 3696781 ttggtttatt ttcttgcagt ctgctttatt ttttatcggg agttcctttt atgtgaaatc 3696841 ggtgatccgc gagagaaaaa acagggcatt tgcatactgg tcatggggat atcacctgct 3696901 gctccccttt ttatccgctc ttttcggagc aggatgggcg tttctcgctt ttatcccgag 3696961 cagcttgcgg gcatggtttt ttcatggaag ggattggccc gtaaaaacga ttggcattct 3697021 ggaaatcgtg aatgcctgct tctttcttgc cgtcatgtgc ctgtttatca caaggtaaaa 3697081 aaacaaggac accgctgtcc ttgttttttt cagtcaatat tgcaaatctc cagcgggcaa 3697141 ttttcacact caatctcaca tcgtaaatag tcccgcttgt gcaaaataat ttttccggat 3697201 tcgtctatcg aaataacccc ttttttgcgg agatctccga gcatacgatt gacgctttcc 3697261 cgtgcagccg cgcaaaactt tgccaaatcc tgatttgtca ggacaatgtt aatcagaatg 3697321 ccgtcgcttc gctccactcc gtagctgttt gataagcgga taagggtaga atagagcgcc 3697381 ccctttttgc catgaagaag cagatccctg attttggact gaatcttccg gaggtgcgtg 3697441 ctcatccatt tcatgaactc aaatgtcaaa gcgccgtttt ggattaattc tttttccagc 3697501 ttatttttat taatgacgag cacctcgcca tcctctagta cttttgcact gagcatatac 3697561 cttggttctt cagtgaaaag tgttaattct ccgacgatat catgcttttg gcagattcta 3697621 agcgtcaggt cttttccgtc agatgtcagc ttgccgattt caatgagtcc tgattgaatc 3697681 agataaagct cttctgcatc cattccttcc cgaaacaaat acgtgtgttt ttccattttt 3697741 cttttcgtgc tgatcgattc cagcaattca tacagatcgc tggatataag atcactatca 3697801 gatggtcgaa cagagagaaa attcatgagc tcacctcgaa gaaagtcacg ttgtgtgttt 3697861 attgtaacgt gaattgattt gtacccatcg agaaaaaact aacaatcttg tgaatgcccc 3697921 agtgttagtt gatgctctgg ctgtttctct ccgtgtgtgt tttcattctt tcctgccaat 3697981 acatccatat gacaaggaca aaactggcta acgccacctc tgaaagcgcc ataaacccga 3698041 tcgcgtactg gcctgttgcc tgaaatacac tcgccaatat gagcggagga aaaaagccgc 3698101 ctaaaccgcc catggcagac acaatcccat tggcaatccc cgcttgcttc gaaaaataga 3698161 aaggcaccag tttaaaaaca gttccgtttc ctatgcctga gcagacggcc acggttaatg 3698221 atccaaacgt ataaaggccg attgtcggcg agaacgatag gataatgcct gataatgtaa 3698281 gcccggcaaa aacaaacatc aagatgcgga gcgggctcat tttatcagcc aggaatccgc 3698341 ccgcaggcct gagcagcgta gaaaccgcaa taaagccagc cgtccgcaag ccggcatctg 3698401 caggattcag cccaaaatgc tccaccagaa agttcggcag atagatagtg aaggcgacaa 3698461 aggcaccgaa cgtaataaaa taaaacaggc tcagaaacca tagcacatga tttcggtaaa 3698521 cagctttgat ttgagtctta acagaaactt tgaccttctt ctcatgcctg tcgccaaaca 3698581 atacgtgcag taaggcaaag acagccagca aaatcagata catttgcacg gttgatttcc 3698641 acccgacggc ttgagcgata accggcgctg caaatgtcgt aacggctgtc ccgatatttc 3698701 ctgcaccgta aatcccattg acgacaccgt gcttttcttt cggataatat ttcgggaggg 3698761 aggtcacccc aatggaaaac accgctcccc cgatccctaa gaaaaagccg cctgcgatta 3698821 aatcaaacag agaatccgcg atactgatcc aaaatacagg aaataaaagc aggatgaagc 3698881 tgaccataaa catgagccgc gcgccaaacc tgttcgttaa ataccctaaa ggaatgcgga 3698941 gaagcgaccc gaggatcaca ggaatcgcgg tcactaaaga aatctcaccc ttgcttaaat 3699001 gaatatctaa tgtgatttgg gaaatgagtg atgaaatcag cacccaaacc ataaaccctg 3699061 ccaccaagct taatgactgt aacgataatt gaatgtgttg acggttgatc atttggcttg 3699121 cccctttcaa tgattcaata atcagtctta tcatacaaaa actagccaaa caggattgtg 3699181 aattacatca cacgtttttc tcataaaaaa aggacaaagc ccgaagactt tgtccttttg 3699241 atcgtgatta cattttttcc ggagccgata cgccgatcag ctgaagcgca ttgttcagcg 3699301 taatttgcgt tgccttcatt aaagccaggc gcgcgcggct tttctcttca ttttcagggt 3699361 cgatgacttt ctctgcgttg tagaagctgt gcagagcaga agccagatca taaatatagt 3699421 tagtgacacg gtgcggaatt cgtttttccg ctgcttccgc cactgcctct gggaagccgc 3699481 cgatcgtttt cagcagatcg tattcttttt ctgattgaat atggctgaaa tcaagatctg 3699541 ccgccggttt aagcccctgc tcttcccctt ggcgaagcat gctgcaaata cgggcatgcg 3699601 cgtattgtgc ataatacaca gggttttcgt tagatgttga tacagcaaga tctaagtcaa 3699661 aatccatatg ggtgtctgca cttcgcattg caaagaagta acgcacggca tccaagccga 3699721 cttcttcaat caggtcacgc atcgttacgg ctttaccggt ccgtttgctc attttcattt 3699781 tctcgccgtt tttgtaaagg tgaacgagct gaatgatttc tacttcaagc gttccttttt 3699841 catagcccag cgcttcgatt gccgctttca tacgcgggat gtagccgtgg tgatcggcgc 3699901 cccaaacgtt gatcagctta tcaaagccgc ggtcaagctt gtccttatga tacgcgatat 3699961 caggaagaag gtacgtgtac gtgccgtcct tcttgatcaa tacgcggtct ttatcatcgc 3700021 cgaaagtcgt ggaacggaac caagtcgcgc cgtcttcttc atagacgtgg cctttttcgc 3700081 ggagcgcttc aagcgccttg tcgatttttc cattttggta cagtgaagtt tctgaatacc 3700141 acacatcaaa cggcacacgg aagttttcca agtccttgcg aagcttttcc agctcgtatt 3700201 tcaggccgta ttcacggaaa aacgcgaggc gttcactttc ctcttcgtta acgaaacgat 3700261 caccgtattc ctcagcgaga cgctttccga tcgcaatgat atcctcaccg cggtagccat 3700321 cctccggcat cggtttttcc aatccgagtg cttcaaagta acggacttca acagaaagcg 3700381 ccagattgtt gatttggttt cccgcatcgt taatgtagta ttcgcggctt acatcgtaac 3700441 ccgcttttga aagcacgttg cacaaggaat cgccgacagc cgccccgcgc gcatgcccga 3700501 ggtgaaggtc tcccgtcgga ttcgctgata cgaattctac ctgaactcgt tcaccgtttc 3700561 cgatgttcgt ttccccgtat gcttcccctg cttccagtac agacggaatc agctttgtta 3700621 aatattgatt gttcatatag aaattgataa aacccgggcc ggcgatatcc agtttttcaa 3700681 tcgaagcctt ccctttatca aaatgggcga caatctcttc agcgatttga cgcggcgctt 3700741 tttttgccac tcttgccaac tgcatcgcca tattcgttga gtagtcgccg tgtgttttat 3700801 ctttcggtgt ttctaaaaca acattgggaa tctggctttc ttcagccagt cccgctttca 3700861 gaacggccgc tttgatttct tctttcagca cgtccttcat ttgttccgca atgttcatgc 3700921 gtgagttcct ccctcatacg tgatcgtcat attatgtaaa tgctcctgct cgtctccgac 3700981 atgcatgtca tatgcgatgc tgatacggcc tttttcttca tcgagatcag attgaatcga 3701041 ttttgtgctt gttttcagct caagctcacc aaatgacatt ttatatttag caattgtgga 3701101 agctcccgtt acgaaacgct gattcatttt gacagcgcct gacctcatga ccaggacttc 3701161 gccttcgctt actttcacaa tcgttttgac tttgcctaag tcgtgttctt cataataaga 3701221 tagatacact ttattttgtt ttacatagta aaatccggtg gtgcggaatt cgatgacttc 3701281 ttggtttccg tcatcctcga tcacagactt cacatggagt gttatcggtg tctcttgctt 3701341 cattctgaca cgtccttttc atcattccac tttgacttga atagtataat cattcggttt 3701401 gtaaacttca actgcttcta tcttaccatc attgctcatc agatttgaag ataaacctca 3701461 taaaaagcat ttccttatat agaagagaaa atcatatcac taattacctt taggaaatgt 3701521 tacatttttc cgaaatctat catttccttt tcacattttt ttcaaaatat atgtattgaa 3701581 ttagtaattt gatagtttta agataaaagt acaacataga tctgctagaa aaacaaaaaa 3701641 agggaggatt caattatgaa aaaagctgtc attgtagaaa acaaaggttg tgcaacatgc 3701701 tcgatcggag ccgcttgtct agtggacggt cctatccctg attttgaaat tgccggtgca 3701761 acaggtctat tcggtctatg ggggtaagga tctcccaaaa gggcatagtc attctactat 3701821 gcccttttta agtaaattac aatttttaac taaaatctac ctcttggata tacatacaca 3701881 accgtttttc atttgaatca tatgtatagg ggatggtatt ttgtttatag agcagatgtt 3701941 tccatttatt aatgaaagtg taagagttca ccagcttcct gagggcggcg tgttagaaat 3702001 cgactacttg cgcgataatg tctccatttc tgactttgag tatttggatc tcaacaaaac 3702061 ggcttacgag ctctgcatgc gcatggatgg ccaaaaaaca gctgagcaga ttttagctga 3702121 gcaatgtgca gtgtatgatg aatcaccgga agaccataaa gattggtatt acgacatgct 3702181 caacatgctc cagaacaagc aggttattca gcttggaaac cgggccagcc gccatacaat 3702241 caccacgagc ggaagcaatg aatttccgat gcccctgcac gccacctttg aactgacgca 3702301 ccgctgtaat ttgaaatgcg cccactgtta tttggaaagc tcacctgaag cgctcggcac 3702361 cgtgtcgatt gagcaattca aaaaaacggc tgatatgctg tttgataacg gtgtattgac 3702421 atgcgaaatc acaggtggag aaatttttgt ccatccaaac gccaatgaga ttcttgacta 3702481 tgtgtgtaaa aagttcaaaa aagtcgctgt cttaacaaac ggaacactca tgcgaaaaga 3702541 gagcctggag cttttgaaga cttacaagca aaaaatcatc gtcggcattt ctctagatag 3702601 tgtcaattcc gaggtccatg actcctttag agggagaaaa ggctcttttg cccaaacttg 3702661 taaaacgata aaattgttga gtgaccacgg tatatttgtc agagtcgcta tgtctgtctt 3702721 cgaaaaaaac atgtgggaaa tccacgatat ggcccaaaag gttcgggatc tcggggcgaa 3702781 ggcgttttct tacaattggg ttgacgattt cggaagaggc agggatattg tccatccaac 3702841 gaaagacgcc gagcagcacc gcaagtttat ggaatacgag caacatgtga ttgatgagtt 3702901 taaagatctg attccgatta ttccctatga gagaaaacgc gcggcaaatt gcggcgctgg 3702961 ctggaagtcc attgtgatca gtccgttcgg cgaagtacgt ccttgcgccc tctttccaaa 3703021 ggaattttca ttgggaaata tttttcatga ttcctatgaa agcatcttta actcccctct 3703081 cgtccataaa ctgtggcaag cgcaagcgcc gcggttcagc gaacattgca tgaaagacaa 3703141 atgcccgttc agcggctatt gcggaggctg ttacttaaaa gggctgaact ctaacaaata 3703201 tcaccggaaa aacatttgct cttgggcgaa aaatgaacaa ttagaagacg tggtccagct 3703261 tatttaggag ggaaacgatt tgtcaccagc acaaagaaga attttactgt atatcctttc 3703321 atttatcttt gtcatcggcg cagtcgtcta ttttgtcaaa agcgattatc tgtttacgct 3703381 gattttcatt gccattgcca ttctgttcgg gatgcgcgcg cggaaggctg actcgcgatg 3703441 agcattttgg atatacacga tgtatccgtt tggtatgaac gggacaacgt catcttagaa 3703501 caagtggatt tacatttaga aaaaggcgcc gtttacgggt tacttggggt aaacggcgcc 3703561 ggaaaaacga cactgattaa tacgctgaca ggcgtgaacc gcaatttcag cgggcgtttt 3703621 acactgtgcg gaattgaagc ggaggccggc atgccgcaga aaacatcaga tcagctgaag 3703681 actcaccgtt acttcgccgc cgattatccg ctgctattta cagaaattac ggcgaaggac 3703741 tatgtgtctt tcgtccattc gctttatcaa aaggattttt cagagcagca gtttgccagt 3703801 ttggccgagg cctttcattt ttcgaaatac atcaatagga gaatttcgga gctgtccttg 3703861 gggaacaggc aaaaggttgt attgatgaca ggcttattgc tgcgcgctcc cctgtttatt 3703921 ttggatgagc cgctcgtcgg tttggatgtg gaatcgatag aggtctttta tcagaaaatg 3703981 cgtgagtact gtgaagcagg cggaaccatt ttgttttctt ctcatctgct cgatgtcgtg 3704041 caaagatttt gtgattatgc ggctattctt cacaacaaac agatccaaaa ggtcattccg 3704101 attggagagg agaccgatct gcggcgggaa tttttcgagg tgatcggcca tgaataacat 3704161 aatccctatc atgtctttgc tgttcaaaca gctttacagc cggcaaggga aaaaggacgc 3704221 catccgcatt gccgcaggcc ttgtcattct ggccgtgttt gaaatcgggc tgatccgcca 3704281 ggccggcatt gatgaatcgg tgttgcgcaa aacgtatatc atactcgcgc ttcttttgat 3704341 gaacacatat atggtgtttc tttccgtgac atcacaatgg aaggaatctt atatgaagct 3704401 gagctgcctg ctgccgattt cttcacggag cttttggctc gcccagagtg tcgttttgtt 3704461 tgtcgatacc tgtttgagaa gaactttatt cttttttatt ttaccgctgt tcttatttgg 3704521 aaacggaacg ctgtcagggg cgcaaacatt gttttggctc ggcaggtttt cgttttttac 3704581 cgtttactcc attattttcg gagttgtgct aagcaaccac ttcgtcaaaa agaagaactt 3704641 gatgtttctg ctgcatgcgg cgatattcgc ctgtgtatgt atcagcgccg ctttgatgcc 3704701 ggccgccacg attccgcttt gcgcggttca tatcctgtgg gcggtggtca ttgactttcc 3704761 tgtctttctg caggcgcctc cgcagcaggg caagatgcat tcatttatgc ggcgatctga 3704821 attttcgttt tacaaaagag aatggaaccg atttatctct tctaaagcga tgctgttaaa 3704881 ttacgcggta atggcggtat tcagcggctt cttttcgttc cagatgatga acaccggcat 3704941 cttcaatcag caagtgattt atatcgtgat ttccgcgctt ttgctcatct gctcgccgat 3705001 cgcccttttg tattcgattg aaaaaaatga ccggatgctg ctcatcacgc ttccgatcaa 3705061 gcgaaaaacg atgttttggg cgaaatatcg cttttattca ggcctattgg caggcggatt 3705121 tctccttgtc gtgatgattg tgggtttcat cagcggccgt tcgatttcag ttctcacttt 3705181 tttgcagtgc attgagttgc tgctggcggg agcgtatatc aggttaactg cggatgaaaa 3705241 aaggccctcc ttcagctggc agacggagca gcagctatgg agcggtttct caaaatatcg 3705301 gtcttatctg ttttgtcttc ccctattctt agccatatta gccggcaccg ctgtatcctt 3705361 ggcggtcatt ccgatagccg gtctggtcat agtctattac ctgcaaaaac aggatggtgg 3705421 tttctttgat acaagcaaaa gagaacggct tggaagttaa cctgctgaag actcatcaat 3705481 tttcaactat ttcaatcgcc gcgagctttc tgaaaccgat cgaaagcgcg gcggaacctg 3705541 aggaagaaac gatttatttt tacggcgccg ccgcatacct gaaggagcaa atcattgacg 3705601 cttttggtta tgctgccggc agccgtttca tgtactcagc gaatctcttt tttgatcagc 3705661 agctgaaaac ctgcgggacc cgtttgattc acccattata taacgggaat cttcatgttg 3705721 acgccctgat gaaaactttt gcagacttgt ctttcccttc ttctctttca ttcgaagcat 3705781 ttgaaaaggc caggaatgag ctgctgctga aaatcgaaaa gaaattcact gatcccttct 3705841 cctactcggc ggctcgcttg gctgaggagg tcttcggaaa cccgatgtac ggcacaggca 3705901 tgtttggccg gagagacagg ataaaggcga ttcatcctaa acggtttctc gacgcaacgg 3705961 actttatcgt tgatttagtg tcccagcaaa aacagctgaa catattggga caagtacaag 3706021 catgtgatgt tcggggacat gccccgcaaa cgtccgctgt aacgtccgga agaatacccg 3706081 taaaccggca tgtttttgaa acagagacac gcagcgctgc aggtccttcc gtcttgacac 3706141 tcggatttga ctgcggagag atgaaagatg ccagcgatta tatcaaaata cagctaatag 3706201 acggattact gggaaagtac ggccattccg ctttattcaa gcacttcaga gagaaggatc 3706261 tggcagtcta tcacgttatc acccgttacg atgtcatgaa caatttgctg cttgtttcaa 3706321 tatgtacaga tcagcttcat gagaaagaca ttcccccgcg cgttttggaa gctgtctcag 3706381 cttttcatac agatgagcgg gaactagaac aggcaaagca gtttttacgc aatgaattgc 3706441 tgctgcaatt cgattctccc gaaggtctat tggcctatat gggggtcctg cgccgcttct 3706501 cctgcacgaa agaagccttg ctggatggca tctcagcggt tacatgccgt gatgtattgc 3706561 aattcatagc gaccatcaat tatatcggag ctcatgtagt aaggggatga agagatggaa 3706621 aagaaagcct tttttcaaca gctggatgaa cgaaccgata tcagatacac agacagcgga 3706681 ctaaaaatat tcagattgaa attcccccgc gcccacctgc ggctgtgcaa tgtaaaaatc 3706741 gattttggaa gccgggatgt atgtatacgg gcagaatccg gtgatacact gcttccgtat 3706801 ggcacagcac attttttaga gcatcttctc ttctggcata acggccgcaa tctgtacagt 3706861 gatttttttg cgcatggcgc gcttttaaac gcattcacta cctacaccga taccaatttc 3706921 atgtttacct cattaccgga tcggctcaga caaacgattc ccatcctgct tgatgcttta 3706981 tggaaccact catttgacaa gaagattgtc gctcaggaaa aagctgtgat tacaagcgaa 3707041 attcaaacag cacaccttaa ccatcagctc tcatatcatt atcagctgat cagcatgctt 3707101 tctccctcct caccagctgc cgttttcccc gcaggcagaa tcgaagatat tgaggcgctg 3707161 gacatcagtg atttacaaaa agcctataag gctgcctacc aagcccatcg gatgacgctg 3707221 tttttgattg ggggctcaga aaatacagaa acgcttttgc ctcctcacct ccagctggaa 3707281 aagcgtccgg attatcatgc tgaaagaaaa atcatcccgg catgccctcc agtcctctca 3707341 caaaaaatga tgctgggtga tgaggagcgg atggaagata cctggaccgg attacagatc 3707401 ggcgcacttc ccgggcaaaa cgatctgttg tcgataaagc tttattggga tatcgcggct 3707461 cgtattctat ttcaattaga ttcaccgttt tttcaagaga ttcagcaaac gtaccgcctg 3707521 gaaatcgatc gcttgtcagc cgagacttat atatatgagg atggcggttt cttgatcctt 3707581 cacagtcaag ggacccattc ttcagcttat atcgatgtgg cttcatacta tgtcacacag 3707641 aagaaagaac aggttgccgc ctggcttcaa tacggcaagg actctttgac agacgcgatc 3707701 atttatgaca gcgattatgt gcgtaaatgc ttcgagtggg cagccgagtg tgacaggtgc 3707761 gattgctcgt ttcttgacat gtaccacatc attcaagata tggatgcgca ggttttcttg 3707821 tctctcattg atgcaatggc atcttctaac aaagcgatca ttcacgtttc tcagaaagag 3707881 gcgatcagac aatgaaacaa agcactgtct ttaccctttt attgctgctt ataggtatgg 3707941 cggcttattc cttcggctgg gttcaggccg ttgccgaagc cgccgcccaa tatgtacaga 3708001 tgatcaacaa tgatgctgtg cggctcggac tgctggcttg taccgctgcc ctcctgatgc 3708061 tgcctgcttt tctctatctt cactatgtca cccaatccgt gaaaaacatg acagcagctt 3708121 ttcagaaact cacacagtct catcaaagct gctgtgactt tcagcaacac aacttgtgca 3708181 gccgatatgc agaagacgtc aaatcgctgc gtgacagcta taaaaacgtc cgccaaacat 3708241 acgtgatggc tgccgtgttg tgccaagtca tcatattcgg ctgcatgttc gaaatcgtta 3708301 aagccgtccc tttccgcctt catacgcccc ctgccttttc aatgggactt gcgatgctac 3708361 tgatcctgta tttattgttt tgcatgcgaa cgtatttgcg gcagcttttc cggcacggca 3708421 gcctgttcag aaaagtgttt gcgggagcac tggcagcagc cgggatttgg tggatgctca 3708481 gtttctctat aagtgaactg ctgtttctga ttatcctggc tgccattcag caaatcggat 3708541 catttattta taaacgattc tcttatcaca gcaccgcttc tcttgatcta taaaatagct 3708601 acatcgcaat cgcagacgga cccgcgccaa ccggaatcac cgtcacggct gtataatcac 3708661 ttgtgcggta cacggtcaca gcattgtcgt tgggctgtgc cgcataaata tactgtttgt 3708721 ccggcgttac ggcgaggtca aaggcgccgg ggagagacac gtttgcaatg atcctctgtc 3708781 tggccgtatt aactacgtat aagttattaa tgagaaacgg ttcactatat ggctctagaa 3708841 aataagctct agtactatcg agagaaaata caatcgtcct cagcgtttca aataaacggc 3708901 tgaagtcccc tcccctgctt aatggtgaca aactaatctc cgttacacct ttcggccaca 3708961 gctcaccatt caatacgtac gcaaaatttc cagcgtaagg agttgtaatt aaactgggaa 3709021 attcaaatgt atctatgata ctttctacca actgcccagt atttacatca tatttatcaa 3709081 ccgaccaact gcttccatta gcggtataga catactgtcc attcggatca agagcaaagt 3709141 ctaaagcgcc gggtatcgga atgacatcaa tgaccgattg agaggccgtg ttaatcacat 3709201 atatagatcc ggcggccatc acgtatgcga actcatctgt tggatcaaat tcgatttttc 3709261 tcggccctcc tccaacagta atggtattta tgatggttaa tgttttatta tcaatcactg 3709321 agacaaggtt ggtatttcca tggaggacat acgtgaatgc tttatcgaaa gtaacgccta 3709381 gattagttgg cacgtcagaa aaagggattg tttttacaac agtgtttaaa tctgcatcaa 3709441 taaccgaaac cgtgctgtct ccagtattgg cagtaaacac atacgattga gggtctggtg 3709501 atggcggtaa aacaagtgtc ccggccaccg taagcggact gccgtagaaa ggcggtacaa 3709561 tgagcagatc ttccactgtt atttgactga aatcaggaca gcggccagac tgtgctgcat 3709621 aataaacaac ttgatcaatc tcttcagtat gaatcacaga aacagccccg tctccttgtc 3709681 catattgatt tcgtacaggc gacacactga caagaagcgt aatggtccct tgtactctca 3709741 cagcatatcg aacaccgata tcttctggtt ccggcccagt ctggattaag caaggctcac 3709801 tgatacagga caaattgtct gtactccatg taacagccgc tgacgcttcg gccgtatcaa 3709861 ccttgaagcc ctcagggaaa tctatcggca cttgaaacgg cgcttcccgg ctaatttcct 3709921 catcacaaaa acagaaacaa ttttcctgta aagcagaaag atcattcttt ttcatgattt 3709981 cacgtccttt tagaaatgca caacatgcag cggttaaatc gtaatggcac ccggtgaaac 3710041 cccaagagat atcacagttt cctcagaata atcatctgtg ttgtaaacaa tgatgctctg 3710101 ctctataaaa cgagttgcat acagaaaatc gccattcggg gtaaacgcat agtctgttgc 3710161 tgattgcgga acatttccta taacgcctgc tccatttgga ctgacagaat ataaattgcc 3710221 agtgaagccg tcatataaat acacctctgc tccactcgta aacattcgat attccccttc 3710281 atactccagc tcttgggtgc tgctgatggt aaacgtattt aaatcaataa ccgtcaaata 3710341 attaaaaaag aattcttgtt ctaatacata ggcataccgc tccggccaat ttgtttctat 3710401 ggttgatacg ataagctctc gttcaattgt tcctgtgact tcaccggtag ttaggtccac 3710461 tttttgcact attccaaaat tcagaacata ggcgaataac ccattgggat cgattgcaac 3710521 atcatatcct tccacaggaa tcgacctatc cacagttaac gtatcaattc caatcacata 3710581 aaccgcagta ccggtgaaaa cataagcaaa ctcatgatta gggataaatc taatcaatcg 3710641 aggcggctga tccagcaata tagttgctgt cactgttaat gtgtcataat cgatgacaga 3710701 aatcacatta ttgttgggat gtaagacaaa cacagcgctt ttatctggcg taatttcaat 3710761 acctgccgga ttgtacggaa gagcaatcgt tgtcacaaca gtatcggtgt ttgtatcaat 3710821 cacagaaact gattgatcat ttggattcgc tgtaaacgcg tagacgggtt ccggctccgg 3710881 tacaagcaca attgtccccg tcaccgataa aggactgccg taaaacggcg gaacaacaac 3710941 aaggttctca atcgtgatgt cactgatatc cgggcaatca tccgattcat cggaataata 3711001 gacgacttga tcgatttctg cattgtgaat gacggaaaca gccccgtccc cttgtccata 3711061 ttgatttcgg acaggtgaga cactgacgag tagcgtaacg gttccctgca ggcgcactgc 3711121 aaattgaaca ccgacctcat caggctcagg ccccgtttga attaagcaac ggtcactgac 3711181 acaagaaagg ctgtctgcat tccacgtcac gtttgcaaca gcttcagccg gatcaacgac 3711241 aaacccttca ggtaattcaa tcggtgcttg aaacatggct tctcggcttg cttctccctc 3711301 acaaaaacat aagcactctt cttgttctgc tcctgctttt tctttaaagg aaagcttgtt 3711361 ttttctcatt ccttcacttc cttttcagac atacactgct cacgcagata taacagaata 3711421 tggaagggta acgtgtttgc ttgtacaaat tgctgagggt aaacgcttct ttttgaaaat 3711481 atatctccaa acatgcggtg taacgaaaga aaaaattgcg gtttttttgc gcttctcaca 3711541 agaatgttga tgataaaata tgacatatat agaattatga agggagggat ttgcaaacgt 3711601 gacaggtgtc atatcttctt cttccatcgg agaaaagatt aacgaatggt atatgtacat 3711661 acgccgattc agcatacccg atgcagaata tttgcgacga gaaatcaagc aagagctgga 3711721 tcaaatggaa gaagatcaag accttcattt gtactattca ctgatggagt ttcggcacaa 3711781 cctaatgctt gagtaccttg aaccgttaga aaaaatgagg attgaggaac agccgagact 3711841 gtctgatctg ctgcttgaga ttgataaaaa acaggctcgt ttaactggtc tgcttgagta 3711901 ctattttaac ttcttcagag gcatgtacga gctggaccag cgggaatatc tgtcggctat 3711961 taaatttttc aaaaaggccg aaagcaagct gatattcgtt aaggatcgga tagagaaagc 3712021 tgagtttttc tttaagatgt ctgaatctta ttactatatg aaacaaacgt atttttcaat 3712081 ggactatgca cggcaagcat atgaaatata caaagaacat gaagcttata atataagatt 3712141 gctgcagtgt cattctttat ttgccaccaa ttttttagat ttaaaacagt atgaggatgc 3712201 catctcacat tttcaaaaag cttattctat ggcagaagct gaaaagcagc cccaattaat 3712261 ggggagaact ttgtacaata tcgggctttg taaaaacagc caaagccaat atgaggatgc 3712321 cataccttat ttcaaaagag caatagctgt ttttgaagaa tcaaatattc ttccttcctt 3712381 acctcaagcg tattttttaa ttacacagat ccattataaa ttaggaaaaa tagataaagc 3712441 tcatgaatat catagtaagg gaatggctta ttcacaaaag gccggagatg taatatattt 3712501 atcagagttt gaatttttga aatctttata cttatcaggc ccggatgaag aagcaattca 3712561 aggatttttt gattttctcg aaagtaaaat gttgtatgct gatcttgaag atttcgctat 3712621 tgatgtggca aaatattatc atgaacgtaa aaattttcaa aaagcttctg cttatttttt 3712681 gaaggtggaa caagtaaggc aacttattca aggaggagtg agtttgtatg aaattgaagt 3712741 ctaaactatt actctcttgt ctggctctaa gcactgtgtt cgtggcaaca actattgcaa 3712801 atgcacctac acaccaaatt gaagttgcac aacgaggaat gatttaaccg ccgtccatcg 3712861 gcggtttttt cgtcccctct ttaccaaagt ctcccaatcc atgctatgat cttttcaata 3712921 atcttgaaga gagtggaaat gcagcatgtc tctaaaaagt gtgagaaccc actttactca 3712981 atggaatcga gaaaatgatg tgacggagtt cgaaacgtcg agtgcgacag ttgaacaggc 3713041 agctgagaca atcggcgtaa gcctgtctag aatcgccaag tccctgtcct tcagagggga 3713101 aggagatcag gtgattctga ttgtggcagc cggcgatgcc aagatcgaca acaaaaagtc 3713161 caggcaaaca tttggcttta aagcaagaat gctctctcct aatgaggtgc tggagcagac 3713221 aggccatgaa attggaggag tttgcccatt tggattggct catgatcctg aggtttatct 3713281 tgatgtatcg ctgaaacggt ttcagactgt tttccccgca tgcggcagca gaaactccgc 3713341 tattgaatta acaccgaaag aattatccga attttctttc tcaaaagtgt ggattgatgt 3713401 ttgtaaagac tgggaataaa aaaacatcca gacatcgtct ggatgtttac ttatttcaca 3713461 aacccaagca gcatttcacg gatgattttg ctggctgtgt ttgccgtttg ctctgagtgg 3713521 tcgtataccg gcgcgacttc cactaaatca gcgcccttta cgtttacctc tgaacgcgca 3713581 atttcatgga ccgatgcaag cagttcttta gacgtgatgc cgccggcgtc aaccgttcct 3713641 gtacccggtg cgtgtgcagg gtctaatacg tcaatgtcaa ttgtgacata aaccggacgg 3713701 cccgccagct tcggaagcac ctctttcagc ggttcaagca cttcaaattt tgagatgtgc 3713761 atgccgtttt ccttcgccca ttcaaactct tctttcatgc cggaacggat tccgaatgaa 3713821 tacacattgt gcggtccgat caattctgcc gccttacgga tcggcgtgga gtgagaaagc 3713881 ggttctccct cataatcaac acgaagatct gtatgtgcgt caaaatggat aatcgcaagg 3713941 tctgggtatt tcttgtacat cgctttaatg acaggccatg acacgaggtg ctccccgccc 3714001 atacccattg ggaacttccc tttttctaaa atgctgtcca cgtactcttc aatcatatcc 3714061 aggcttcgct gcggatttcc gaacggcagc ggaatgtcgc cagcgtcaaa gaagttcaag 3714121 tcagccagat cgcggtctaa atatgggctg tattcctcaa ggccgattga cacctcacgg 3714181 attctgcttg gaccaaagcg tgagcccggg cgatagctga ctgtccagtc catcggcatg 3714241 ccgtaaagaa tggcgtccgc ctcttcccac tcgggacggc tcgcgataaa tacttttcct 3714301 gaataagctt catcaaatct catctataat accctcgctt tcctgtaaaa aagcgcaaga 3714361 ttcgctcctg cgccatacct tcattattta atcaggtcac tcacaaattt cggcagaaca 3714421 aacgccgctt tatgaatatc ttttgtgtaa tatttcgtct caatatcgaa gaaacggctg 3714481 tcttccactg caagcggatc atattttttc gagccaattg taaatgtcca caaaccgctt 3714541 ggatatgtcg gaatgttcgc cgtatacagc ttcgtaatcg ggaagatttc cttcacgtcg 3714601 cgctgtacat ttgtgattaa ttccggtgta aaccatgggt tgtccgtctg cgcaacgaaa 3714661 ataccgtctt ctttcagcgc ttttgcgatt cctgcgtaga atccttttgt aaacaggttt 3714721 acagccggtc cgactggttc agtcgaatct accatgatga cgtcatattg attttcagat 3714781 tttgcaatgt gcataaatcc gtcatctacc tgcacgtcaa cgcgcggatc atccagtttg 3714841 cctgcgatag aaggaaggaa ctttttagag tattcgataa ccttgccgtc aatatctaca 3714901 agtgtcgctt ttttcacgct tgggtgcttc aggatttctc tgataacgcc gccgtcaccg 3714961 ccgccgacta cgagaacgtg ctccggattt gggtgcgtga ataatgggac atgcgccacc 3715021 atttcgtgat aaacgaattc gtctttttca gatgtcatca ccatgccgtc caaaaaaagc 3715081 atgttgccga actcttctgt ttccaccatt tctaaatgct gaaactccgt ttgttctgta 3715141 tgtaacgtct tgttaacctt catcgtaatg ccaaagtttt tcgtctgctt ctctgtgtac 3715201 caaagttcgc tcaattgtca tctccctttc gaggctgtat tcatttattg taagcgtctt 3715261 atcagctttt attctcggtt gaaatctcat tttcacctaa ggaaaaagta tagaggatgg 3715321 cggggaaaaa gtaaagatgc gtcctgttct gcgatgttta aaaacgatct ttttttctca 3715381 taatagtaga aacataaaaa aagggggaac ccgttgtgga tgcaatgaca aataaacggc 3715441 tgagactgac gctgaaaacc gttcgcgcct ttatcttttt aggggctttt gcggccttgg 3715501 cggcagctgc tgtgtttatg actgtcattt tgatagccaa ataccagggc gctccctcgg 3715561 tgcaagtgcc gcaatccacg attttgtacg cgagtgacgg ctcaaagctc ggggaaacga 3715621 actacggcga aaagcgctat tgggtcccct taaaggacat gaatccgacg atcgtaaaag 3715681 cgacagtggc gattgaagac cagaatttct acgatcatca cggctttgat tataaacgca 3715741 tggccggcgc ggcgcttgct gacctgaaag catttgccaa ggttcagggt gcaagcacca 3715801 tcacccagca atatgcgaga aacttatacc ttgaacacga caaaacgtgg aaacggaaat 3715861 ggaatgaggc gttctacacg atccgtctgg aacaaaacta ttctaaggac gagatattag 3715921 aaggctattt aaatacgatt tactacggcc acggcgccta cggcattgaa gcagcttccc 3715981 gcctgtattt cggcaagcat gccaaaaacc tgacggatgc ggaggcggcg cttttggcag 3716041 gaatcccgaa aggcccttcc ggctattcac cgtatgtcaa tgagacgaag gccaaggaac 3716101 gccagaaaac gattgtgcgg atgatggaaa agcagcagat gatcagccaa aagaaagcgg 3716161 atgaattgat caaggaacct ctttcctatc agcctttgaa taaacaagtt tccaagagaa 3716221 aggctcctta tttctacgac aatgcgatga gagagctgga aaaaaagctc ggcatgacac 3716281 gggagcaaat tgaaacgagc gggttaaacg tctatacaac ggtagataaa cggatgcagc 3716341 gcatcgccga ggagaccatt accgaaacgg ttaacgcggg ctctgacatt caagtcgggt 3716401 tttcagccat tgatccccgc accggaaacg ttctcgccct tgtcggcggc agggattatc 3716461 aaaaaagccc gtttgaccgg acgacacagg cgaagcgcca gcctgcttcg acgatcaagc 3716521 cgttgctgta ctataaagcg attcagagcg gatttacgcc agtcactttg atgaaaagcg 3716581 aagaaaccga gtttcaaatt gatgcaaagg gagaaaccta ttctccaagc aactataacg 3716641 gatactatgc caacaagccg attacgcttc tgcaggcgct ggcgctttcc gacaatattt 3716701 acgctgtgaa aacgcatctt tttctcggca cgaacaaact tgtaaagacg gcaaaggaat 3716761 tcggcattac cgcccatctt caagcactgc cgtccctggc actcggcacc gaacccgtac 3716821 gtccgattga gatggtcaac gcctatgcca tgctcgcaaa tggcggaaag aaaatcgaac 3716881 cgacttttat ttcaagagta acggacgcag ccggccacgt gctgtacgaa aacccgaatc 3716941 agcataaaca ggtgcttgat gaaaaagccg cttttgtcac agcgagtatg atgacaggca 3717001 tgtttgatat cgatttaaat ggatatacgt cggttacggg gcgaacgata gccaaccgcc 3717061 tgacaagaac gtatgccgga aaatcaggaa ccaccagcgc agacagctgg atgatcggct 3717121 tcaatccgaa gctggccgcc ggtgtttgga ccggctatga caaaaacagc accatcgact 3717181 cggtcgaaga aaaaagctat gctaaaacca tttgggcgga cttcatggag gacgcgctca 3717241 aaggcgaacc ggaaaccgcg ttcaagccgc caaaaggcgt aaccggtgtg tacattgatc 3717301 cggaaacagg ctactcatca ggtcccggct gcgccgctaa gcattacaca tattttgtga 3717361 aagggacaga acccgcaaac gtgtgctacg gggcagaacc cgcaaaacaa acaaaagacc 3717421 ggcttccatc caaagaaaag cccgcttccg agaaaaagtg gtgggacaaa tggctggggc 3717481 gacatcattg aaaataaccc ggctcctcgg aggccgggtt attcgtatgg ttccttcata 3717541 atcgatggaa gaatgttaga caatcgagct gaacaatcag ttttgggata aagtggtgaa 3717601 tttctcattt cttcggcgct ggctttcatc tcccagtcgc cgactcatat ccccctaaaa 3717661 atgaaaaacc ccgagtcttg tttcggctcg ggattttcca tgtcctattt ctgtatcacc 3717721 agtttactca atgtttacga aaaatatctc aaatacttta aaagttcaca aaaaattcat 3717781 aaattaattg ttttctggaa gcaggctcgt ttttaactca tctgaggaac ggtcccatag 3717841 gccctgatca tgctttttca gaaattcgcc tagtacacgc ttcgagctgt cgtccatttt 3717901 atcaacgatg attttccgtt tcatggattt atccatcaga ttcacatgct caggcagtga 3717961 cttgtagcct cttctgatgc ttctgtcgac cgtcatttca caggctgtca caccagcgta 3718021 ataaggcccc tcttcttttc tgtcaatcgt tacccacaca agccagtatg gttttccgtt 3718081 cggcacttct tctttattcg ggagaaattt aattcctttt tcaacggtgc tgcgggcatg 3718141 catagcgccg atgtctacga acgcttcttt ttcctctaca tcaacgaata cgggagaaat 3718201 gttatcaagg ctgagtgccc ctacgccaaa accgccgtgt ccgtctgtcg gatcactttt 3718261 gataatatta aacccgattg attttttctt tttttcttcc atgaagttct acctcctaca 3718321 aaagcggttg aaatatcgct gaaaacagct ttaaaatcga atctcttcct gcattgagca 3718381 tcggccacag cacgtaagat cctagcggtg tcacaaacag caccaaaaat acgataaagc 3718441 cgtagctctc cgcctgcgtc attttggcac gcacgcccgg cggaacgaga tcttctataa 3718501 ttcgatagcc atcgagcgga ggaagcggca gcagattaaa taaaaacaag acaagattca 3718561 gctgtatcca aatagaaaaa aactgatcca gccccgtgct gaacgccgca agcatttcca 3718621 ttccgtacgc atgcatcaac actaacaaaa agaaaccaat aaacgcaaga atcaggttac 3718681 tgacgggccc ggctatagat acgagcacac cagcaagccg gggtttctta aagaaacggc 3718741 gattcacggg aatggggcgc gcccacccga atccggccac cagaatcaaa atggttccga 3718801 acggatcaag gtgtttaatg ggattcagcg tcagtcttcc ttgttttttc gccgtatcgt 3718861 caccgaattt gtatgcgaca taagcgtggg caagctcgtg catcgtaaac gacacaatta 3718921 gcgtgatgac gaggtatggc attaaagata acggataata taaaaaacgg tccaagtgag 3718981 atatccctct ttctcaaaat gcaagaattt actttattca gtatactata agaagcctct 3719041 ttttctaaag agaggaaacg agataaagga ggattcagca cccatgccat acgtaactgt 3719101 caaaatgctc gaaggccgta cagacgagca aaaacgcaat cttgtcgaga aagtaacaga 3719161 agccgtaaag gaaacaaccg gtgcttctga agaaaaaatt gttgtcttta tagaagaaat 3719221 gagaaaagac cattatgccg tcgcaggcaa acgcctgagc gatatggaat aatctctata 3719281 aagccggcgc ttcgcgcacc ggcttttatt atccctattg agccagcttc gcaataatcg 3719341 ccaagaacgt ctttttctct tcggctgtta aacgttcaaa catgccatca atcagctgct 3719401 ggcggttttc gatcatttgt tcagccgctc cccggcccga ttcagaaaga gtaatccata 3719461 cagtgcggcg gtcattgtta tttctggatc tctcaataaa cccttcctgc tctaaatgat 3719521 tcagagctgt ggtcgtggca gagggagaca gtgtgacctc cttcaaaata tcctttatgg 3719581 tgcagctccc atgtctgtat atgatccgca gaataaaccc tcttacatta ttcacgtgtt 3719641 tcggaacggt ggcttcatct aattgcttcg tgcttttcaa atactttgta agtgcgtgat 3719701 ccagcaaatt tgcttccagt ttgtcatggt ccatgtcaat ttccccattt cgagatgcat 3719761 tcataacata cgaacgatat gatttactta ttattttact gattccgaat agggaaagtc 3719821 aaaaaagcaa aatgtgaatt cacagctttt atcctacatg cctcgatttt ccacctgttt 3719881 cacaagttta tctttaaaag tttggaaagg aacgtgttca ttctgctgat gtccgaatcg 3719941 gcggacgttt accgcattct cctgctcctc atgatctcca agcaccagca cgtacggaat 3720001 tttttgcacc tgcgattctc tgattttata gccgagcttc tcattgcgct catcaatgcc 3720061 ggctcttatc cccgcctgct tcagctccgc ctgcactttt ctgcaatagt ctaagtgaac 3720121 gtgcgaaacc ggtatgattt gaacctggat cggtgcgagc cagactggaa aagccccacc 3720181 gtaatgctcg atcaaaatgc cgaagaaacg gtcgattgag ccgaaaaccg ctctgtggat 3720241 gacaacggga cgaaccttct cattgagttc gttgatatat gttaaatcaa atttttccgg 3720301 catttgaaaa tcaagctgaa ttgtcgcgca ttggtggctc cgtttcaggg catcttttat 3720361 atggaaatca attttcggcc cgtaaaacgc cccatcgcct tcattgatct cataagagag 3720421 gccaagctcc tcaaggacgc gtgctaaggc acgttccgac gcttcccaaa ggctgtcatc 3720481 gcctaatgaa tcctccgggc gagtcgaaag ctcaacagaa tactcgaaac caaatgtccg 3720541 atatacctca tcaatcagcc gaatcgcttc tttgatctca ctctcaatct gatcctcccg 3720601 aacgaaaata tgggcgtcat cctgacagaa cgtccgaacg cgaagcattc cgtttaaagc 3720661 gccgctgtat tcatggcggt gcacctgtcc gaattccgcc atgcgaatcg gcagatcccg 3720721 ataagaatac aggctgtttt taaagatgag catgtggccg gggcaattca tcggcttcat 3720781 tgcgaatctt gtatcatcca cttctgaaaa gtacatattg tcgcgataat ggtcccaatg 3720841 gcctgactgc tcccataacc gctgattcat cataaacggc gtacgcacct catcgtagcc 3720901 ggcatttgtt tgcagctcac gcgagaagcg ctccagctca ttgcggacaa tctgcccttt 3720961 cggcaaataa aacggcatcc ccggcgcttc ttcagaaaac ataaacagcc ctaactgttt 3721021 gccgagcttg cgatggtctc gttttgccgc ttcttctagc atatgcaggt gcgcatccaa 3721081 atcttttttc ttttgaaacg caaccccgta cacccgctgc aggacttcat ttttgctgtc 3721141 tccgcgccaa taagcgcctg atactcttgt cagtttgaac gccttgatca tccctgtaga 3721201 aggaagatgc ggccctcggc acaggtcaac gaattcccct tgctggtaca gtgtgatatc 3721261 ctccccgcgc ggaatatcct ttaaaatctc aagcttgagc cgctcgtctt tttgtgcaaa 3721321 cagctcttca gcttcttcgt aagaaacctc tatacgtttg atttcaaggt tctcatttat 3721381 tatgtttttc atttcttttt cgatggcctc taagtctcct gatgccaagc ttttccccag 3721441 cttcatgtca tagtagaagc cgtctaaaat cacaggccct acccccaatg acacttcgcc 3721501 gtacagccgt tttactgctt gggccagcac gtgcgctgtt gtgtggcgaa gcacctgcaa 3721561 gccttcttgt gaatcgagtg tgacaatcga aagctcagca tcctcctcca gcttgaaact 3721621 gagatcaaca agcttgccgt tgacctgacc tgcggccgcc ttcttttgca gactggaact 3721681 gatcgaacca gccgcttctt tgattgtgat gcctttcgga tattcctgga tctgtccgtc 3721741 cggaagctga atgtgtacat gtttgctcat tttagaacac tccttattca ttgttgtata 3721801 taaaaaaaca cacccgtccc gcagataggg acgagtgtgt gattaacccg tggttccacc 3721861 caagttcccg acaaatacta tgttgtcggc tcggtgctgt aacgcagcat agacggcatt 3721921 ggttacttca gttccccaat gctgctccaa ggcggtaaat gatattccta agctgggaag 3721981 ctctcacctt tccttccctc tctgaaaacc gtaactatca ttcatgtcct tttcatcgca 3722041 tgtattcaat tcataaaaaa acacacccgt cccacagata gggacgagtg tgtgattaac 3722101 ccgtggttcc acccaagttc ccgacaaata ctatgttgtc ggctcggtgc tgtaacgcag 3722161 catagacggc attggttact tcagttcccc aatgctgctc caaggcggta aatgatattc 3722221 ctaagctggg aagctctcac ctttccttcc ctctctgaaa accgtaacta tcattcatgt 3722281 ccttttcttc gcatgtattc aattcaaata aaaaaacaca cccatccctc taaaagggac 3722341 gaatgtgttg atcatccgtg gttccaccca aattcccgat caattacaca tgatgatcgg 3722401 cttaaagatg ctgtaacgca gcatgacggt atcagatact tgttttccct gatacggctc 3722461 aaaggcggta agctgctttc cctgcgttag gaagatctca gctgtccttc cctctctgga 3722521 aaccgtaaaa agcatctcgt gtccttatca gtgcctgttg tttcaataat tttttatatc 3722581 ttactatata ttcccacaaa gcgcaatcag tgatttacat tttttctgac gcggcagtcc 3722641 cgttatgggc agccagaaac agccatacaa gcaatgcagc gaggctgtat gccgctccca 3722701 tcatcaaaaa cgcaaacccg gcaccagcat accaagtggc ggacagatga atgatcaccc 3722761 cggttatcgc tacgccgacc aaggctccga tttgccggtt tgcatttaac gccgcaccgg 3722821 cgatattcgt atgtctttgc ccggcagcct gcatgatcac agttgtcatg gcaggaactg 3722881 taataccggt acagaggttc ataacagaca tcaacaccgc cagctgccaa taaggaaaat 3722941 ccggagaaat cagcacaaac aacagcaatg caatgataca gctgaccgcc attgatacaa 3723001 acataagctg accggcttca aaccgattcg ccagacgggc aaacagcaga ttgccgatca 3723061 cgaagaccgc catcatcggc agcagctcca ctccagccat aaaggaactt gcccctcctg 3723121 cttcctgcaa aaaaaggctg agcataaaca tgccgccaaa aagggcgaaa ttcagcaaaa 3723181 acccgataaa ttgggcagct gagaagcggc cgtttttgta taaggacgcc ggcaggatgg 3723241 gtgtttttgc agaaatttcc cgcagcaaaa acagcacaaa tgccaaaacc gctgcagtaa 3723301 atgctacaag aatcactggc gagcgccagc ccgctgaagg cccctgtatc aaagcatagg 3723361 aaagaaaccc gagagccatc atgccaagca gatgcccgat gatgttcacg cggctgcttt 3723421 tcccaggaac gcggctgagg attcggtaag ctgaaatgag cgcagcagcc cctattggca 3723481 cattgatcag aaaaatactc tgccagcccg ccaactgtac cagcacgccc ccgataaaag 3723541 gcccaagggc tgaagcggcg gaaacaagcg cggcccacag tccaaacatt ctcgcccgcg 3723601 cccgctcatc aaggtaagag gcagccaaaa ggctgagtga gcttggcata aacaaagctg 3723661 ccccaattcc ctgtatgaga cgtccggcaa tcagcatctg cccatttata gatgcagcgc 3723721 atagacagga ggccataaca aaaacggcta gacccaagat atagatcgtc ttcgagccga 3723781 aacggtcagc caaggctccg cccgccagca gaagcgacgc aaaagtaaga atgtacccgt 3723841 ccacaaccca cgttacacct gaaagtgaca ttgaaagagt gtttttcata tcagccatcg 3723901 ccacattcac aacggtcaca tcaagagttg ccatgaggaa accaagtgcg agcacgatca 3723961 gcacggatat gcctgttgat gatgttgatt cttgtataga cccgctattt ttcattacaa 3724021 ttgccctttc acttgcttga ttacccaatc atctattttt tcaagatcat acaattcccc 3724081 gactctgtcc ataacatgct gcaaggattc ttctctcata agattggacc atttatcctc 3724141 gatttccgcc atgactgtct ccagcacaca gtgactttca ccctcaaata cagattgcag 3724201 caagcctttc ccctgataca tcgaacctct gccttcgacc gcttgataaa catcataaag 3724261 cgtaatgtca gccaaaggct tcgtcagggt aaaaccgccc ttcgtccctg gtaaggattc 3724321 tgccaaaccg gcttgaacca atgttctcat cagcttcttc aagtaagacg gagacacgcg 3724381 caatcgctgg cttatagcct ctgacgtcaa agaagcctgt accggcagcc gtgacagtaa 3724441 cagcagcaca gaaaccgcct gctccattcc tgatttcatt ttcatcctat tcactcctga 3724501 ttcattatgg ataactatta tccataatga atctcttagc agcttttgtc aataaaaaaa 3724561 gcaaaagaaa cggatcattt cttttgcttg gtatggttaa caaatctgct tcagttcctc 3724621 tatgtattga agcgcttcgt catattcttc atttgtatat ttttgcttgc ttttgatggt 3724681 aaagactttt tctttctttt cctcatcctc aagcccgtca aagtaaagga tcgtggaaac 3724741 cagctctaaa aaccgtgatg aacggctgtt tacactgtcg atatagcctt tcatatccgg 3724801 catgtccaga tcagcatggt ctaaaaatgc ggagcctgtc tcagtcagcg aataccggta 3724861 ttgaaagtag ccgccctttt tttccttcac ctcatgcaga aatccaaggt tgcacagctc 3724921 ttcaatctgg agcgtcagtt cctctgaata tggtccgtaa aagtgaaaat catatttctc 3724981 atagaaagga aactgcattt tcttggcgat ataaatcatt ttctgcagct tctttcgccc 3725041 gatgatttct ccagaatccg agaacacctt catcagtttt gcatgttctt tcaacaaatt 3725101 cccgacatct cctttttcct tctttccaat ttctatgtca gtcccagcag ctgccggatt 3725161 ttcattttcg cttccggatg tttagtgccg tcacaaatca agtcctttgg atagtacagc 3725221 ttgtggtccg tccgccgttt acctgagatg gattccacaa tagccgactg tctggacagc 3725281 tctttaattt ggccgttttg cgtcaagaga tggatcggca gacgctcctc ttcctctcct 3725341 ggtcggtaaa aatcgtatgg cagatctgat gaagaatcaa cgaccaaata atagctcgga 3725401 tcgatccccg cctctttgaa caatgaagtc agctcaaaat aagccgacat ttcttcattc 3725461 ggattgaatt caacgtattg gaaaagctgg cggttaatga atctgcggca caagtcggat 3725521 aaaatcgcgt cttcttcatc ctcccaggcc tggaagtaat acaaaataat agattcatcc 3725581 agctttacat aatcctccag tgtcaatttt ccttcaaaaa tagaatagaa atgaaccgga 3725641 gcgtgagtga agacatagcc ttcatcgtgc agctgcttcg ccctgtgaag aatcttcgtt 3725701 aaaatgacct ctgcacttct agtcacagga tggaagtaga cctgccagta catttggtaa 3725761 cggctcatga tatagtcttc gacagcgtgc attccgcttt ctttaatgac gatctgatcc 3725821 tcgcgcggcc gcatcacccg aagaatccgc tccatatcaa aatggccgta gctgacgccc 3725881 gtataatatg cgtcgcgctg gaggtaatcc atgcggtctg cgtcaatctg actcgaaatc 3725941 aggctgacca cttgcttgtt tttatatgtt ttggcaatga cttcagcaac atcctgaggg 3726001 aaacccgggc tcacctttct gagcacctga ttaacctccg tgtctcccaa aatgatacct 3726061 cttgtaaaat cctcgtggtc aaggtgaaag accttttcaa atgaatgcga gaacggcccg 3726121 tgcccgaggt catgaagcag cgccgcggcc aaacagagtt cgcgctcact gtcatcccat 3726181 tcagggcggc ctttaaagac gtcatcaacc attcttctga caatttcata gacaccgaga 3726241 gaatggttga accggctgtg ctcagcccca tggaacgtca aataggtcgt tccgagctgc 3726301 ttaattctgc ggagacgctg aaattcacgg gttccgatca aatcccatat cagcttgtcc 3726361 cgaacatgaa catagcggtg caccggatct ttaaacactt tttcttctga taattttcca 3726421 tttggatacg ccatcgtcat tccctctttt ttttagccgt gtttctatta tatcgactct 3726481 attctttgaa aacatccttg aatttgcccg gcgatttgtt ccatcttcat gaaaaacaca 3726541 tcttgtgaag caaaaaagcc tgacctgagg gccgaggcta agaaaaaata tgtttttact 3726601 tttttatttt cttttttact ttgtcaatca gctcatcctc tgtcggagct gacagcgggc 3726661 gattgttcac aaaagcaaat gattttttcc gtccgggccc gcaataagat tggcatccta 3726721 cctcaacctt tgcgtccggg tccacttctt tcaaacgcgg cagcaatgtt ttgatattag 3726781 tggcttggca atcatcacac actcgaaatt cattagccat gacgtacgct tcccttcatt 3726841 tctatgttca tctatgtgaa taacctaaaa tcacgtttca aaaaaaatca catcacactt 3726901 cattttacaa ggattcgact gttcctgcaa gccgctccat ccttcgtatc tcctattctt 3726961 tcagccaatt tgtataaata ttttccaacc tggacattct aataccatga aaagaaaaat 3727021 gggagttgag ataaatgaca aaacagcgac aagacgcttg gtcagaggaa aacgatctgc 3727081 ttttagccga aacagtgctt cggcatgtga gggagggcag cactcagctg aacgcctttg 3727141 aagaagtcgg cgataaatta aaccggacat ccgcagcctg cggattcaga tggaacgcag 3727201 tggtccgcca tcaatatgaa aaagcgcttc agcttgcgaa gaaacaacga aaacagcgga 3727261 tgagagcgct cggaaacggg cagcccgcga aaaaaagatt attatatcag cctcctgccg 3727321 ttgatcctga aatcattcaa gaaaccgctg cagaagagcc ggttaaaacg gaaacaccat 3727381 ctgtcgaaaa tgagcaacct ttaatgtctg gcgaacacat gccttttgtt gatgaaagct 3727441 ttaaggaaga gttagctagt ctatcacact tattgtctcc tcaaacgcct gcagctgcgc 3727501 ctgagatgac gatgaatgat gtgatccgct tcctgcagaa ttacgaaggc aatcacgagc 3727561 aatcatcagc attaaaaatg gaaaacgagc gtttaaagaa agaaaatcag gaattgcaaa 3727621 acaaaacaga gcagctagag gcagaagttc aaaagcttga aaaagaccaa aaaacgatcc 3727681 aagaagatta tgaaaccttg gtgaaaatta tgaacagagc cagaaagcta gttttatttg 3727741 aagaagatga acatgcctct ccgtccttca aaatggaccg gaacggcaat ttagaaaaat 3727801 tagcggaatg acatagaaaa atcccaaaac gggcagctgt tttgggattt tcgccatgtg 3727861 caaaatcccc ttttctattg agaaaagaga atttcctcat tttgcagccg gatcagctat 3727921 tcttgtaaaa tgaggccaag cttatgtgaa tctattaaga catgtgagct gcctcggccg 3727981 ttttttgttt ccgaggcgca gcagaaatga ccaaaagccc cagcatcata agcgcaatgc 3728041 ccagccacga ggaaggcgaa agcatttccc ctatgaaaaa cacgccaagc aatgaagccg 3728101 tcagcggttc agctaaagac agcgtgaccg ccgccgaggc cggaaccccg gtaagccctt 3728161 tcgcaaacaa aaagtatgcg gcacatgttg caattaaccc gatgtaaagg cttgttccca 3728221 gtcctctagg ggtcaatatc cacgagatat ctaactgcca taatagcggc gtcagcaaga 3728281 tggcgctgat catgaataca acggcggagg tcgctcgcgg aggctgggtt ttcatcatcg 3728341 ctttactgat gagcgtatag cctgcaaaag aagcacccgc tccaagcgcc ataagaacac 3728401 cagccacatc aatccgaaca ttggaactgt cggaaaacag aagccagcaa cccgctaaag 3728461 ccagcacagt cgcaatccac caggagtttc gcgggcgttt cttcaataca gcccattcga 3728521 gggtcccggc aatgataggc gcactgccga tggcaatcac agttcccact gcaattcccg 3728581 tttctttaac cgctgtgaaa aacagcggct ggtaacacgc catacaaaca gcggctaaaa 3728641 atacgagcgg ccatgcccaa tttttcacgt gaagctcccg gctgatccaa accgcaagca 3728701 gcatggcgct tcctcctatt aataacctga acgctccaaa tgccagcggt gtggcgcttt 3728761 ctggagccaa tgcctgaacg gttcccgtgg tcccccagaa aaaagccgca atcaatacaa 3728821 aaaggctgta aatattcccc ttcatctgcc tctccccttt aatatggatg ctgatgtcat 3728881 tttatcgttt ttctttttgt cgtggttatc tgtatgtaag aaggacttat ctgaaaataa 3728941 gattattgag gtaaaatgcc gcttgagata aaaaatgcat gccggcatat acagccggca 3729001 tgcgaagaac gttcacccaa atacctttgc attccgctca gccatccgga cgaggttttt 3729061 ctcaaattcc atttcctcat caatggacag tccagctgaa taaagatggg tgcttaacgc 3729121 ttttaattcc gtcaataaag cgaacattaa gtcttgtacg gagatgtctt tttgaagaag 3729181 ctcacttaag gacgccatcg tttccggacg tatttccgga tagacgcctt ttttatcgtt 3729241 ttgtttgtct ttcagcgccg cttgatagaa tcgtctgatc aagtcggccc tttcactgcc 3729301 gcttttatct gcacagagat aaatttgaac agcgactccg ccgcgaacgc gtctctgaga 3729361 gatgccggcg aactttttgc catttatact gaggtcatag ctgccgggac aataagaccc 3729421 ttcaatttca taggcttcga tctttgcgtt gtacggtctc agcattcgtc tcatcagctc 3729481 gaccatcgct tcatatcctt tgtctatatc gatgcctttc ttttcgtcct cgaatatgag 3729541 agagatattt aaaacaccgt catccaatac gacggcaaga ccgccggaat tgcgtacgat 3729601 cacacggtat ccttcgctct ccagcaagga gataccatcc tgcaaaaacg ggaggcgtgt 3729661 atcctgtatt ccaaggacaa ttgtatcgtg gtgcacccat gagcgcgctg tcgccggcga 3729721 cacgcctttt ccgacggaca tgcatagcgt atcatccatt gcgaaggatt gcttcgcatc 3729781 aaataaaggg ccgagactgg attggtcaat gactctccat ttcggctgca tcagtaaatc 3729841 aatcggttgg tttgccatct atgtaaaacc ctttcatgtt aggcttattg aacgaaaact 3729901 attatatcat ttcagcagct gtgattgata attgcttttc agcatcgtaa taaaaatttc 3729961 tttatttttt gtattctcca tgagaggaga atgaatgtaa gacagcttgc gctttaacga 3730021 gaaattatta atatgcagaa ttgaaatttc gcggtggatc aaatccttac gcagcacgct 3730081 tctggataga accgaaagtc ccatgccgtt aatcaccgct tcctttacac cttgattgct 3730141 gctgatggta aacattgatt tcggccgaag tccatttgaa ctgagtacat gatcgagata 3730201 ttctctcgtc ccggagcctt tctctcttgt cacccacgct tcgttctgca aatcgctgat 3730261 cgaaatctct ttccgcccgg cgagcggatg ctgatttgga gcggcaatgc acatttcatc 3730321 ctccatgaac ggttcaattt ccagctcatt ctcgtttgta tgtccttcaa tcagcccgat 3730381 atcagcctga agcatccgca cacgctcgct gacctcctct gtattgccaa tcatgacatc 3730441 tagattcagc tctggataca gcttttgcag ctgggccaat agcggcggaa gaatatactc 3730501 accgattgta aagcttgcag ctattttcaa ttcacccttc acatagtgat gatgcgcata 3730561 gatttcagcc ttggcttgtt cgtagagaaa caccatttgc tttgctcttt gatataaaat 3730621 gtctcctgtc ggcgttgtcg taaagtgttt tggcgacctg ttcagaagag ccgtttgaaa 3730681 ttctttctca agatttttga tatgcagact gacgctgggc tgggagatca tcagcttttc 3730741 cgccgctttt gtgaagtttt tttcttctac caccgctata aacgttttca gcacgtcgta 3730801 atacaaaaac cccacccctg tcattaatga aatatatggt tatgattagt tttctttatt 3730861 gtactcatat catccgtctt ggtaaagaag ggctatacag aagcgcaaaa aaggcagccc 3730921 tcggtcgaga gctgccattg tcttcaattt tattacagtg cttgcgccgc tgtaattaat 3730981 gcgagattgt aaacatcttc agcgttacat cctcttgaaa ggtcgtttac aggcatattt 3731041 aaaccttgca ggattggtcc taccgcttca aagttgccca aacgctgagc gattttatag 3731101 ccgatgtttc ctgcttcaag acttgggaat acgaatacgt tagcgtcccc tttgatctcg 3731161 gaatccggcg cttttttctc agctacagat ggaacaaatg cagcatcaaa ttggaattcg 3731221 ccgtcaagtg tcagttcagg cgctttttct ttcgcgattt tcactgcatc cgctactttt 3731281 tctgtttcat cagattttgc tgagcctttt gtagagaagc tgagcattgc cacgcgaggc 3731341 tcaatgtcga acatttttgc cgtattggca ctttcgatcg caatctcggc aagatcttgg 3731401 ctgtcaggtg caatgttgat cgcgcaatct gcgaatacgt attgctcttc tccgcgagcc 3731461 atgatgaaca cgcctgaagt ctttttcacg ccttcttttg ttttgatgat ttgaagagcc 3731521 gggcggacag tgtcagcagt tgagtgagca gctccgctta caagtccgtc tgcaagtcct 3731581 ttatacacca gcattgtacc gaagtagttc tcgtctaata atgctttacg agcctgttct 3731641 tcagtcgctt tgcctttgcg gcgttctacg aatgcttgta caaggtcttc catgccttca 3731701 tatgtatgag gatcataaat cttaacgccg cccagcgtaa ggttcaattc ttttgctttt 3731761 gcttggatct cattttcatt gccgatcaca atcggattca gcactttgtt tcctgcaagc 3731821 ttgctgaccg cttctaaaat acgctcgtct aagccttcag gaaatacaat tttaacgtct 3731881 tttccagcta ctttttcttg cactgttgaa aataaatctg ccacaataaa acctcctcaa 3731941 aaagttacaa aaacgctttc ttttactagc atactcttct tccaatcaaa ttcaaacagc 3732001 caactttcat tatagcgctt tcataaaaaa atcttatttt tctaactaat ttaagtgact 3732061 caatcttccc ttataggttc ttctattttg atggagttat acggaaggga tgttcaaggt 3732121 ttctccacag tagaatcgga taaactatgg tatagtgaag gcaatcatga aaagataatg 3732181 ggagtgaaga taaatgagtg aacagcaaat gacgaatgaa gcggcaaaaa cgcttgacgg 3732241 ctggtatgcg cttcatgatt tccgcacaat ggattgggct tcctggaagc ttctgtccag 3732301 tgatgagcgc caatctatca tacatgaatt caccgggttg cttgaaaaat ggggcgtagc 3732361 ccaaaaagaa ggaaaaggat cgcaaactct ttacagcatc gtcggccaaa aagctgattt 3732421 tatgctgatg atccttcgtc ctacaatgga agaattaaat caaattgagc ttgaattcaa 3732481 caaatcaaga cttgctgagt tcaccattcc ggcatactcc tacgtatcag tggtagagct 3732541 gagcaactac ttggcaagcg gtgacggcga tccttatgaa aatccgcatg tgcgcgctcg 3732601 cctttaccct gaactgccgg aatctaaata tgtatgcttc tatccaatgg ataaaagaag 3732661 atctggcaac gacaactggt atatgctttc aatggaagaa cgcagaaact tgatgagaag 3732721 ccacggttta atcggccgca gctatgcggg caaagtcaaa cagatcatca ccggctctgt 3732781 cggctttgac gattacgagt ggggcgttac attatttagc gatgatgtcc ttcaattcaa 3732841 gaagctagtg tacgaaatgc gttttgacga agtcagcgct cgctatggcg aatttggttc 3732901 attctttgtc ggcaatcacc tttcgcttga tacacttcct caattcttat atgtataata 3732961 tcccctcccg ccctatccgg cgggagtttt tcaattctcc tttatcagaa tttaaataaa 3733021 atttgctatt ttcttcgttt tttcttacga tgtagataat aatccatttt tttcaaaggg 3733081 gtgcagttat ttgtcaaaac gaaccgcatt tgttatggga gccagtcaag ggatcgggaa 3733141 agcaatcgct ctgaaattag cagaccagca cttttccctc gtcattaatt cgcgaaattt 3733201 ggataatatt gaatctgtca aagaagacat tttggccaag catcctgagg cgagcgtcat 3733261 tgtccttgcg ggcgatatgt ctgaccagca tacgagagcg ggcatttttc agaaaatcga 3733321 atctcaatgc ggacggcttg atgttctgat taataatatc ccgggcggcg cgcctgacac 3733381 atttgataac tgcaatatag aggatatgac ggccacgttc actcaaaaga ccgttgccta 3733441 tattgacgca atcaagcgtg cttcctcact gatgaaacaa aacgagtttg gcagaatcat 3733501 caacattgtc ggaaatctgt ggaaagaacc cggcgccaac atgttcacaa acagtatgat 3733561 gaatgccgct ttaattaacg ccagtaaaaa tatttccatc cagcttgctc ctcacaacat 3733621 tactgtcaac tgtctgaatc ctggttttat cgctacagac cgttatcatc aatttgtgga 3733681 aaatgtgatg aaaaagaaca gcatatccaa acagaaagca gaagaacaga ttgcttccgg 3733741 gattccgatg aaacgggtcg gatcagccga agaaaccgca gcgctcgccg catttcttgc 3733801 ctctgaggaa gcctcctaca tcacgggaca gcaaatttcc gctgacggcg gcagcatgaa 3733861 aagcatataa aaacatcccg ctttttagcg ggatgtttct tgtaatgacc cgaacggcag 3733921 gttcagcttt tgaatccgcg tgacaaattc ccgcagatcc tcctgcttcg acaccattga 3733981 gattctgaca tgcctttttc cgttgcttcc aaaaatttcg cccggtgtga ctacgacatg 3734041 ggcatgctcc agcaagtaat cggaaaattg gtgagatgtc tcaaacgtat tcggaatttc 3734101 agcccatacg taaaaggttc cttttggctt ttccatcttc cagcccagtt ccttttcaca 3734161 aagcgccgta aaaaagtcaa ttcgttcctt ataaattcgt ttcaacgatt ccgtatgctc 3734221 cggatctcca gaaagcgccg cactcgctgc ctgctgcagc ccgccgaaca tgccgacaaa 3734281 tacatgatcc tgaaattcat tgacggcctg aatgattttt tcgttcccaa ccgcaaacgc 3734341 cattctccag ccggccatgt taaatgtttt tgaaaatgaa taaagctctg ctccgacagt 3734401 tttggcatcc tctgcctcaa gaaagctggc cggtttttga tcgaattcaa acgccccgta 3734461 tgcaaaatca tgaatcaaat ggatgttatg ctctttcgca aaagcagcag cttttgcata 3734521 aaaagccgca tcagccacag ctccagtggg gttgttcgga tagtttaaaa acataagctt 3734581 cgctttttcc agcacggctg gatcaatctt ttcaaaatcc ggcagatagc cattttcttc 3734641 atacagcggc atttcgtaaa gctcagctcg cgccatcgta atccctgata aatattcagg 3734701 atagcctgga ttcgggacta aagcgatgtc tcccggattg agcaggcatt gtgtcagcac 3734761 atacaatccg gctttcccgc ctccgaaaag cgcgacttcc gtttcaggat tgattgtcac 3734821 tccgtattcc cttttataga aagcggcgat cgcttccttt aaaaaaggat agcccctgaa 3734881 agggccgtat ccatgaaacg aaggattcag agaagcctcc cgcaaagcct cgacaatatg 3734941 cggcggagtg ggaaggtcag ggttcccctg tccgagatta atgatatggg ctcccgtttt 3735001 ttccatttcc tttacctttt gaaaaacgag agaaaactcc tgccttggaa gtgtcttgat 3735061 gacatcggac ggtgttattt ccatctaaaa gactcctttt tgctccgttt tgttatcccg 3735121 ttccaaaaac gatttgttga cgagcttcgt atgcaaaaac aaaccgcata cgatcacgac 3735181 aatcagcccc ataatgaccg gagcgcttag gatgttaatg aacattgaac caatagaaat 3735241 gcataatccg atagacgctt cggccactga aaaaatgcgc ccttgaatct ggtttgccgc 3735301 attttcctga accttcactt ttgcaagcac ttccccgtat tccatcgcga tgaaaaagag 3735361 gatcgccgcg atgacagaaa cagcgaatat cggtgtgaat aaaaacagcg ccagcgagac 3735421 aatggataaa acggtaaagt acgtcaggcc tctattgttg ttaaagcccc atttgctgac 3735481 aagcgccgct ccgataaagc cgccgaagcc gatgcagaac gtgagaataa agttgccgat 3735541 ttccccgtca cccagaaagc ggctgacaat cggaaaatag ctgtacacaa ctccccacag 3735601 caaagccatt gtaatcatcg taaacatggc gtttaatacg aatgaattgg ttttgatttc 3735661 cttgagtcct tccttaaaag actgaaaggc ctctttaatg ttttcagatt gaatcggcac 3735721 aaattgcagc ttgatgcggc tgataaaaaa tgccgaaacc aagtatgtca caccgttaaa 3735781 ggcaacagcc agctctacag atccgcctaa cagaaagagc cctccggcag ccgccccgac 3735841 gataatggag atggttgtcg cttttgcaaa taacgtgttg atgcttttaa tatctgattc 3735901 caaggacgac atgacagcga gacgggcggg attaaaaaac acgccgcttc cataagtaat 3735961 aaacagcagg gccagaaaaa tcagcggata ctcgcctttt ggaagaaatg tgagccccaa 3736021 aaagatgatg cctctgatga tatccgtcca cagcatgatc ttaattctgt ctaaccggtc 3736081 gaccagaaca cccaaaaacg gctgaaacac catcggaatg cttctgacca cgatgacccc 3736141 ggacgtcacc caataatcgt gataatatgt agacaaaatg agcagggcag ggagaacaca 3736201 atagtctccc atgaacgata gcgcctgccc gtaaagcaag tatttagagt tgggtttcag 3736261 ctgtttcata ctggcagcac atactttgcc gtcagcttcg catgctgctg aatttgtctg 3736321 attgattcag ccacatcctg tgaattactg cctttcagtt caaatgcagc aatggaattg 3736381 aaagcttcaa acaatgtcaa atcaactgaa gtgcctggtg ctgcggccga aaaagaaacg 3736441 atttcagtat ccccttttaa aagcccgtcc ggaatatcga tcgcttcaat gaccaaatcc 3736501 tcagcagttt caggaatttg gccattttgt ttgaaatgct gcgggtacaa atggcagtcg 3736561 gcaacataat aaggctcttg atccaataat ccgtccggca gatcggcgtc ttttccgaaa 3736621 cagaggacat ctaataataa ttgcgccata tcaaggccaa agaccttttt aatattgggg 3736681 atcatattcc agccggcaaa tctggctgcc gactctatta aacccggttc tctgtttttc 3736741 attagcttga tctctgtatg tgttgcgcaa ttttgcagtc caagcccttc atttgccttt 3736801 ttggcagctt cgacaatttt cttttttgcc tcttcatcca gaatggacgg cgtaatgtgg 3736861 gatgtctctg taaacccgat ttgcggcgtt ttatcatgaa tggcgatcgg gaaatactca 3736921 ccgtcagcca tgatgccttc tatactgata tagtcggagt acccttctgt ttgataccag 3736981 tctccgtact caccctgtaa aaattcttca gcgataaacg gcgcttcaaa cgtaaccgcc 3737041 tttggcacgt taattgattt cagatagtca ttgactctgt taaattcatc ttctgccgtc 3737101 tcagtgtccg taatcagcgt tacaccgata gaactcgcta agtatgtagg ctttaagata 3737161 agaggtgtgc cgatctcttc aagagcagca cggaaatctt caagagttgt gactcgtttg 3737221 tttttgatcg atttgactcc ggccttatta aaagcgtccc tcattttatt tttatctctg 3737281 gcattttcgg ctgcctgcac gccggcacct ctcaagccca gacgttcaca ggctttcgcc 3737341 atcggagcaa tgaataattc attgtttgtt gtgatggcat ccgccccaaa catttcggca 3737401 accttgacga tttgctcgac gacctcttcc tcaggcttgt tatgatcttc atgcgcccaa 3737461 taaatggaat cagggtgttc aaaatcagct aaactcttaa aatagtcttt atcttttatg 3737521 accgcgaccg agtatttttc aatcaatgct gcatgggagg ctgtaattgc aaaaggtctt 3737581 ggaataaagc tgaccaggtt atatttttca gcagcgcttt tataaaacat gtgcggcggg 3737641 cagcctccaa gatcagcgat gaccaatact gtttttctct ccatatgtaa aacactcctt 3737701 ctctattgtg cggtgtatcc tccgtctgcg gtgatggcgc ttccggtcat atagcttgat 3737761 aaatccgagg ctaaaaacag catcacattt gcgatttctt caggtttccc aagcctcagc 3737821 agcggattta ccttcgcttt ttctttttta atctcttcaa gtgtgccttc attattttca 3737881 aggaatgatt tttcattcag cggtgtgtcg atgatccccg ggcatacgca gttcacccga 3737941 atttgatgtt tcgcataatc aacggccatt gatttagtca gctgcaaaac cccgcctttg 3738001 ctggcgttat aagcaggaat atcaggccat gccacgagtc cgccgacaga gcacgtatta 3738061 atgatgttgc ccttgccggc ggccagcata tgcttgagtg catgtttgct cattaaaaac 3738121 atgccggtca aattgacttg cagcaccttg ttccaatcgc tgagctccat ctcgtgaata 3738181 ggcgccacga tttcgatgcc tgcattatta atcaagacat cgagcccgcc aaatgtatga 3738241 accgccgatt caactgcgtg ctggcaggca gcttcgtctg tgatgtccgt ttgcacaaag 3738301 tgcagcctgt cattattttc ttttcgtacc attgcttctc cttgcgcttc atcaatatcc 3738361 gccacaacca cattggcctg ctggcccaaa aaagcctgaa ccgcagcata accaatgcct 3738421 gatgcgcctc ctgtgatgag gacggtttta tcggtgaggt tcatgatcat tcatccgcct 3738481 tcattttttt tgcttttgcc ctgttatagc gcggcgggaa gaagatatta atcgattttg 3738541 attctttttc tgaacggttg atggcaccat gatcttcgcg aggctcacag aaataggctg 3738601 tgccgaattt catctcgact gtgcagcctt cgaccgtcat gtcatagccg ccgccgatgc 3738661 agatgcctat ttgttcattc cgatgtttat ggaaaggcat ttctccgcca tttccaggga 3738721 ttttggcaag cataatttct acccaatcct caacaaagaa cgtgacttcc atgcccggca 3738781 gcaggtctct tgttttgaaa atatccaaaa agtagtcctc aggacttgta tatgtttcat 3738841 cagctttcag ccgcttgata tcaatagcaa tcacttcttg gtctgtgtcg tttcttgccc 3738901 cgtgaggcac atgcggcggc gcgatatagg cagattccaa ggctgtcatt tttcttgtca 3738961 catctccgac agtcatcatc agctcgccag aaacgaccat gccgatttgg acctccttat 3739021 gctgatgggg ttcaacattg gtatgcggcg ggacgtaaga cattaatact tcagtatccc 3739081 ctcgtacggt tgaatactgc ctcactccgt tttcccattc aattaatttc ggtgtcggga 3739141 aataaagctc ctgcatatct tctttagttt tcatcatcaa cgtctccttt tccaaataat 3739201 gaccagctca ttggaatgct tttgaatgtt tttacaaagg ttagcccgta cttttgccgt 3739261 gcaagctcat tggttaaggc aatgtcatac aaaccttctt ttacttttct tgcggcttga 3739321 ctggttgaat tgactagttt gaaacgaaca tctttgcggg taaaatattt tattaaatta 3739381 ataggtgaag gatgtgaaac aataacagat gtatcaagca tatcgtctct gaattcaaaa 3739441 tcaggacgaa cagccaggcc gtacatcggt gtatcgcacc tgaagatctg caatagctgc 3739501 aaatccggcc tcatgtagaa atgcttaatg ccatcgtaag catgtgggac gatggtatat 3739561 tccagcgggc tttggagcgt cctttcgatg cacgattcaa aagtatcatg caaggacaat 3739621 ttactgttca gcccttgtag aagagtaaaa ttggaaatga aatgctttgc tgcgtactca 3739681 ctgcttgtcc cctcagggcc gagcgtgttg actgtaatga gtttggatag tgaatcagtt 3739741 cttttttttg tctgaatgct attatccaat ataatcatga gcaccaacca atcttttaaa 3739801 attttaagta aattttatcc agtggaaatt gaactgtcaa tgttttttga aaatattgat 3739861 aattattccc atacaaacaa aaaaaccctt taaaaagggt ttttaattat aggaatttag 3739921 aaactttgtt tattgagata aggactgatc ggccttctgc tcaagtttgc cgtacttttt 3739981 atatgcgaat acactgagca caaatccgag gactgtgatg gcggcgcaaa tcaatccgac 3740041 agctgcatag ccgtatgcca catatacggg tcccattaaa gcagaaccta atgtcacggc 3740101 cagattcgag gcgagactgt aaaacaccat gacttttcct cgatgacgct ctgagcagtc 3740161 actcaaaatg gtgctgagca gcgtcaccgt caaactttgc attaatcccc aaataaatag 3740221 gctggcgatt aacagaaaca tagacgccgg cgcatatggt aaacacgcca gcagaacgct 3740281 gatgaccccc agcgcaatca aaagggagcg catttttccg atgcggtcgg ctatctttcc 3740341 tgtaatcaca ctcatggaaa acccgattcc ataaatcatg ataaataagc ccgcagccgt 3740401 gtttcctccg gtaaaaacgt cctgaagata ggtgcctaaa aaggaataca taccgtaaaa 3740461 accaatcata ttacaaaagg ttattgtgat ataaacaggt acacgaggga ctttcagcgc 3740521 atcccggaat gttcctgcgg gctcttctat ttcttccttg ccgctgtttt tatgttgggc 3740581 atggcggcgc atttcaagga gaatcagcag aacaactaaa acacccatca gggcgaaaat 3740641 ccaaaacgtc catctccaat gcaggacgcc gccgataaat gatccgagcg gcactccgaa 3740701 aatcagcgcc agcgaccagc ttgaaacgat cagtcccatc accttgcccc ggtatgtata 3740761 aggaacacga tcaccgacaa ctgcgtaagc ggtcggaaca aacgctcccg cagccaatcc 3740821 cgaaagcgcc cggcctaaaa agaagaaaaa aatattttga gctaaagcgc atatcaccgt 3740881 tcctatgata aaaatcataa gcccggccaa taagctcagt tctctggagt atttatcgcc 3740941 taatggaacc aaaagcggcg caccgataaa aatcataacg ccgtaaatac tgatagataa 3741001 cgcaaggacg ctgacatctg agctgaaggc ttttgctaaa tccggcagca gcggtgagat 3741061 cacaagctct tcagatccgg ctgcaaatac ccccatcgtt aaagccagtg ccaacaataa 3741121 cggaaaatga tgttttgttt tgatgtcatt gttttgattg ctgttcattc tttctcaaac 3741181 acctcttcca taatcttctt atcataaagt tgtattatag tttagcattg ttttttctct 3741241 atttacaatt cgaacgaaat atttataagt tttattattt tcatttaaat cccattatat 3741301 atttctatat ttcattctaa aaatacatga ggatgtaaca cgtaaaaaaa gctctccggc 3741361 ctcccggaga gctttttcta ttgcgcctct gtctgctttt tttcaatcgt ttcatgattt 3741421 atacgctttt tgatgcttag atgatagtat gcataacaga aaataatgat cggcacaccg 3741481 cagtataagc caattctttg atccggaatg aaaataaggc tgatcaacac gcagccatat 3741541 aaacaaaatc cgagaatcgg gactagcgga taaagcggcg ttctgaactc cagatcattc 3741601 acatttccgc cttctgccag gaaacgcctg cgaaagaaaa attgcgacgc acaaatggac 3741661 atccacgcga caactgtcac catgcccgag attgagatac accataaata cactgtttct 3741721 gcagccatga cacttgtcag cagcgaacag cctgaaatgc ctagcgtaat cagcagggca 3741781 ttcatcggca cgcctttttt tgtcagtctg gtgagaaagg agggacccat ttgatttgat 3741841 gaaagtgacc acatcatacg cgacgccgca tacaatcccg aattagcaac agataaaatg 3741901 gccgttaaga tgacaaagtt catgatatct gccgaaaatg ggatgccgat ttgatcgagt 3741961 actgctacaa acgggctttc aatcaccccc gccgttttgt acggaaggat ggcaaccaag 3742021 acgaacatag cgagcacaaa gaaaaacagc gtgcgccaaa taacatttcg aatggacttt 3742081 ggcagtgttt tttccgggct ttcactttcc cctgccgcaa tgccgacaag ctccgttccc 3742141 tggaacgaga agtttaccat gaccagcgta aacataacgg ccagcacccc attagggaaa 3742201 agccctctat cagtcataaa gttagacaaa aagggtgtct cctgtccgcc tttaaagtca 3742261 atcaagccaa acacagcggc tccgccaatc acaataaata atatgatcgc cgccactttg 3742321 atgcttgaaa accaaaattc catttccgca aagcttctga cagagagcgc attaatcaaa 3742381 aagatgacga tgccgaacac gaggcaccat atccagatcg gaacggaggg cagccacctt 3742441 tgcatcaaaa tgcctgctga cgtcagctct aaccctactg tattggccca gctgaaccaa 3742501 tacagccagc caatcataaa gcctgtcgac tgtcccagaa atttagtggc gtaggcctga 3742561 aacgatccgg ccaccggcat ggcaacagcc aattctccta aacaaagcat gacgagatac 3742621 attaaaaatc cgccgatgat atacgcggca atggcgccga gcggtcccgc ctggctaatg 3742681 gtaaagccag agcctagaaa cagcccagtg ccaatcaccc ctcccaaagc aatcataaac 3742741 aaatgcctgc ttttcatgct gcgctgcaat tcatttttat gattctgcat catccttccc 3742801 cctttggttc ttttgccgtg atggtcatcc ggtagctttg caaaagatga acggtggttt 3742861 gctgtatgag gagaggcaat acatgaaatg tgtacggttt atagactcgt tctgtccatt 3742921 tatggccgtc ttttccgtac acgcccatat taatggatgg aatattcagc ttgcgtatgt 3742981 ctttgaacgg aatggtccca atcatattcc acccagggaa gttcctgata aaagaatcaa 3743041 tttcgccatc ggtttcgtgc agtgataaaa aactgccgtc tgccaagtag gggaaaaact 3743101 ttttgaagac aaatgtttcg cctgtcgatt cagcggtttt gtcagccgct tctttaatca 3743161 catgctgcaa aagctgatct cttgcgctat cttctttcaa atagttatgc ggcaggtaag 3743221 gaggtgcgta aaatagaatg acttttgcgc cttgatcggg gtcaagcttt tgaagctctt 3743281 cgattgcctg aaagcatctc atgcgaagtt caaggtgctc gttggctttg aatgtctgct 3743341 cgatacactg ctcgggatct attccccggt ttctcagctt ttctaagtat tgctccaggc 3743401 tatacacttg aatgccccat gataaatgtt tctttggcag gttggctctt tttacatatt 3743461 cttcgtaata atctgataat ttttgttctg tctcccggca tgcttcctca gtgacttcaa 3743521 taagcaaatc catcatttct tttgctgttc tttcataaat aaaacaattg aaatacaagc 3743581 tggtgctgac agccgtttgc acattatagg attccttgtt atcacgctga tacaaacagg 3743641 atgggggcag aaccaactcc ccttcaacct tttctgccag atggatgtta ttgtggagac 3743701 ggcttgtgat ttcagatgaa atgaaatttg ggtcaatccc tgccagtgta tcgccaacat 3743761 ggacttcacg cccgtaaatg taaaagcaag gcaacagttt tcccgcggct ccggtataga 3743821 tatatcttgt ctgatcacca tcgtaaagcg gggtaataaa atccgtatta atagcagcca 3743881 aatagtgaag ctgtttttct ttttttagcc ggttcagctc tgaaatgctg gcgagaatgc 3743941 ccgaatgctg gctctcctca tcgggattgg ccataaacaa tacatttccc ggcaacgtct 3744001 caaggttctc cgaaaaatgc aggagattgg ctaaatgcac ggcgatgccg ctttgcatat 3744061 cgacagatcc tcttccgaac atccactcgc ctgatttggc atcccgctga acatcctgat 3744121 cgaactcata gcggctgaaa tactcggcca atttctcaca atcaaaagcg atatccttta 3744181 aagggccgaa atcttcaatt ccaactgtat ccagatgggc atggtaaatg actgtatttc 3744241 ggctttctcc atgtccttta ataaacgcaa aaatattttt gcgtttgtat gggtcattgg 3744301 gaatggcctg ttcccacaca tgactggggt tttcctgaaa ataaggatag ctcgtgatca 3744361 cttctttgat gaaatctgct tttgtccctt ctccaacggt gccgttcacg ctgctgaggc 3744421 tgaccagaga tgctgtcagc gcctccactc tttcagccgg attcatgtga ctgatttttg 3744481 tatactgcat aaattgtcct cctgatcaaa aagttgaaat cgtgcgatcc gctaaagaat 3744541 cgcacgattt tatttctctc aaatcaaaaa gcttcggacg ttgttttggc ttgcatatga 3744601 agaattaagt aatcgggacc gcctgctttt gagtctgttc ctgacatatt aaaaccgccg 3744661 aacggctgat agccgacaat tgctccggta catcctctgt taaaatatag gtttccgaca 3744721 tggaaatcct cgcgcgcccg ttcaatgtgc gcacggtttt tcgtcagaag cgcacctgtt 3744781 aatccgtatt ccgtgttatt ggcaatctcc agcatatgat cgaaatcacg cgctttgcaa 3744841 atcgcaacaa ccgggccgaa aatttcttcc tgcatcaagc gggcgttttc atcaacatct 3744901 gcaaagatcg tcggctgaat aaagtagcct tttgaatcat cgccttctcc gccggccaat 3744961 agcttgcctt cagatttgcc gatttcaatg tatttcatca ctttgttgta ggatgcttca 3745021 tgaatcacgg gacccatata cgtatcagga tcttctggat tgccgacagt cagcgttttg 3745081 gtcagcgcca cagctttttc caccacttca tcatacacat cctgatgaat gaccgcgcgg 3745141 gagcccgcag aacacttctg tcctgaatat ccaaatgctg aatacacgat agaggatgca 3745201 gcaaggtcaa gatcagcgtc cttgtcgaca agcactgtgt cttttccgcc catttctgca 3745261 attacccgtt tgagccattt ttggcccggc tgcactttgg cagctcgctc ataaatccgg 3745321 cagccgactg cacgggaacc tgtaaatgag acaaaccgtg tcttcggatg ctcaactaag 3745381 aaatcaccga tctccgcacc atctcccgga atgtaattca gaacgccgtt tggcagaccc 3745441 gcttcctcca tgacctcgac aaattttgct gccactaccg gggctgcgtc agccggtttt 3745501 aagagaatcg tatttcctgt cacaatcgct gccaccgctg ttcccgccat aatcgcgagc 3745561 gggaagttaa atggagaaat gacgatgccg acgccaagcg cttcgtaatg atattgattg 3745621 acctcgccag cacggctctt caccggagcc ccttccttga gctttaacat ttggcgcgcg 3745681 tagaactcta aaaagtctat cgcttcagcc gtgtccgcat ctgcttcctt ccacggtttt 3745741 cctgcttcct tcacaagata gcttgaaaat tcatgctttc ttctgcgcaa aatagccgct 3745801 gccttaaaga gaatatttgc gcggtgctcc ggtctttgtt ttttccagga atcaaatgcc 3745861 tgcaatgcgg cttgcatcgc tttttcagca agctcttgat ccgctgtaga cgcgtaccca 3745921 atgatctctt ctttatttgc cgggttaata gaaatgattt tgcggtccgt ttcaattttt 3745981 tctccattta tgacaagcgg ataatgcttg ccgagctgag tgtttacaaa ggccaatgac 3746041 tccccaaatg cagttttatt ctttgcttcc gtaaaatcgg taaatggttc gtgcgcgtat 3746101 gtgactgtca tatgtagtcc ccctcgtgtt atgaaatata tcttcgcata tgaataaaaa 3746161 tgcaagaatc atgccatttt cttgtctttt gctgaaaaaa cttgttgaat cgaacagaaa 3746221 tttgtctaac aggtgatcac ctttctcttt ttccgatctt gaacgcaaat ttattttgcg 3746281 ttttttgctc tttacgcaaa aaacaaatgc aaaattattt tgcggaggct tctcaaatta 3746341 gacccatccg cggaaacgcg atgcttctgc cgattttctg atgcccgtca tgtaagccgc 3746401 caaacgcata tccactttat gtgttgccgc tgtttgataa attgtttcga acgagctgac 3746461 catgacgctt ctcagttttt ctgcaacctc ttcttccgac caataatatc cttggttgtt 3746521 ttgcacccat tcaaaataag aaaccgtgac gccgccggca ctcgctagga tatccggcac 3746581 aagcagcacg cctctttcat tcaggatctt agtggcatca atggttgtcg ggccgttcgc 3746641 cgcttcaacg acgattgacg cctgaatgtt atgtgcgttt ttggctgtga tttgattgga 3746701 gatcgcggca ggcactaaaa tatcgcaatc cttttcaagc agctcctcat ttgtgatgac 3746761 gtcagtaaat aaattggtga ccataccaaa gctgtcccgt ttatcgagca aataagggat 3746821 atcaaggccg tctgggttgt agagcccgcc attggcatca gaaatcccga tcaccttcgc 3746881 gcccgcatcg tgcatgaatt tggccaggaa gctacccgcg tttccaaagc cctgtatgat 3746941 gatgcgcgcg ttttgcagct tgatcccttt tttcttcacc gcctcttcaa tacaaatcgt 3747001 gacgccctgt gccgtcgctg tttcccgtcc ttgcgatcct cccaaaacaa gcggtttacc 3747061 tgtaataaag cccggagaat cgaattcccg cagccggctg tactcatcca tcatccacgc 3747121 cataatctgc gaattggtgt acacatcggg agctggaata tcctttgtcg gaccgacgat 3747181 ctggctgatg gcacggacat accccctgct cagcctttcc agttctccaa atgacattgt 3747241 ccgcggatca caaataatac cgcccttccc gccgccgtaa ggaagattgg caatcccgca 3747301 tttgagcgtc atccaaatgg ataatgcctt tacttcctct tcattaactt ctggatggaa 3747361 gcgaacgccc ccctttgtcg gaccgacagc atcattgtgc tgtgaccggt agcctgtgaa 3747421 cactttgacg ctcccattgt ccattttgac cggaatgcgg acagtgagca ttctctgcgg 3747481 ctctttcatg agttcataca tatctcccgg ataacccagc ttccgaaggg cttccttaat 3747541 gattgtttgg gtagacagaa ataagttaag agcttctttt tcttcatctt tcgagacttg 3747601 ctttgctgac atctttttca cctcattgtt tttttggccg gctgtaatgt aagcgcttta 3747661 aaaaatcagc ccgccaattc ctttcttcat tggattcacc cttatcatca tgcaagatcc 3747721 gtaccagctt ttgaatccac aaaaaaagag actgaaaaca tctcagtctc tgactacaaa 3747781 tctatcgatt aacggggatc aatcaccagc tgcgtttcag cataaaaact gccgattccc 3747841 aaaccgttta ctacatcgcc tttaatcgtg taagtgcctg cgcgaggaag agttttacgc 3747901 accatgacaa ggtcaaattc ggatgcgcct aacaaatcaa gcgtaagcgg gagtctgact 3747961 gtttttccat cgtttaaaat ctgtgtttct ttcagtgttc ttccattcac tgaatctctt 3748021 gtcgtagcat gaaacccgtc aggaaattga aattctaccg ctccaagaga aagcaccgca 3748081 tttggtttat atgtcacttc aatatcagaa atggtccact ctttcgtgct gttaactgtt 3748141 tttgcctcga ttgatgcaga ctgtgcatga gcttggcccg aaggaagtaa gattgatagt 3748201 aaaacagctg aactgatgaa taatgaagat acgaatgaag ttctttttag catgacattt 3748261 ccccctaatt gattgttgaa atttggccag agcgtcctct gcagaaaaag cgctttttca 3748321 taattcgcga attaccagtt ctttttctta aaaattaatc tatcatcatt ttccatggaa 3748381 gtaaatgttt tttaaggaat attaacactt ggaattcaat gagaattcct tcctgtttat 3748441 acaaggttca aatggacgat ttccctctct ttttctagta acatctgcct gacattttat 3748501 atcttttatc ctattttaaa aaagggcaaa aaaagtcgaa gatgcctctg ctcttcgatt 3748561 gatcacgttc ctatttttat ctgaattcag tgttccagtt aaaaccgatc gtctcatcat 3748621 cccacggaat tcttttttca tcaggctgat ccgggttata cgacatggtg gtaaaataga 3748681 taattgtcag cggcgtctct cccagcactc tatatccgtg agccacccct tttgggatta 3748741 ataacagcat cgggttgtct tcgcccatat aatagacgtc cgtttctcct tttgtctttg 3748801 aatcctctcg aagatcgtat aggacaacct gagcgtggcc ggttgggaag aaccagagat 3748861 catcctgctt ctcatgataa tgaaatgcct taatcacacc cggatagctt ttcgaccaag 3748921 aggcctgccc aaaatgctca aggagattct catcgtcccg gaccagctca gcaaaaaagc 3748981 ctctgtcatc gctatgcttc atcaattttt tcaccttgac tccatcaatc acacgcactg 3749041 ctcctttcct gcaaatactc tcgtaacgct tcccgccagt ggcgggggcg gatgccggct 3749101 tcttcaatag cccgatggct cagcacagag tatgccggac ggggcgtttt gttcccgtat 3749161 tcctctgtcg ttacagacaa aatggctgtt tccagcccgc tttcttccat aattgccgtc 3749221 gcaaactcat accagctgca tatgcctgaa ttgctgacat gatagatgcc cggcggatgg 3749281 ctgaacagct tgatgaccgc ttctgctaaa tccttcgtat aagtcggcga accaatttga 3749341 tcgctgacaa cccgaagctc ttgtttcgtt tcagcaagtt tcagcatggt ttcaacgaaa 3749401 ttactgccgc catgtccgta cacccacgat gtcctgatga tcgtgctgtc ttttgtcgtt 3749461 aatcgtatca gttcttctcc gagccttttg cttttgccat aaatggtttt cggatcgagg 3749521 ggatcgtctt ccctatatgg ctgggttcct ttcccattga atacatagtc cgtgctgata 3749581 tgaacatatt gagctccgat gcgggttgac tcaagcgctg tataataagc gccgattccg 3749641 ttaatcaagt acgctttatc aagctctttc tcgcattgat caaccgacgt aaacgcggcg 3749701 ctattgacca cgatatccgg ctgataatgg ccaaacgaat gccgtactga gcgctggtca 3749761 gcaatgttca tcatcttctt tgttaacgca atgacctcat atccggcttg cttcagctgg 3749821 cggcatagtt ccaagccaag ctgtcctccc gccccagtca ccaatacctt tgtcaatcag 3749881 atcaccttct catcggtcat tgtctgtata ccactgaatc gtacgcgcaa tgccttcttc 3749941 aaacgtcact tcctgccgcc agcccagttc gtttttcagc tttgatgcat tgatcgcata 3750001 gcgccggtca tgcccttttc ggtcttccac gtgggcgaac aattcctcac agcccagatg 3750061 cttcaaaatg acactcgcca gctctttatt cgtgcgttca tttccgccgc cgatgttata 3750121 cacctcgccg tcggtccctt tttctaaaat cagcttgatc gcgcggcaat gatcctccgc 3750181 aaacagccag tctcggatct ggagtccatc gccatacagc ggaacaggca ggccctgctt 3750241 cgcatgacgg ataatcgtcg gaatcatttt ttcgctgtgc tgataaggtc cgtaattgtt 3750301 gctgcatcgt gtaatgatgg ccggaagctt gtgggttttc acataagaca acacgagcaa 3750361 atcagagctt gctttgctgg ctgagtatgg gttattagga gaaagcggcg tcgtttctgt 3750421 aaacgcggga tcatccgctt ttaaatcccc gtatacctca tctgttgaaa tatgaatcag 3750481 cttcttggct tttcctttca agaccgcttc cgccaatcgg tatgtcccca tgacatttgt 3750541 ggtgataaac ggctccgctt gggaaatgct tctgtccaca tgcgattctg ctgcgaagtg 3750601 aatgacgcca tcgtaggtct cgtcaaaagc gcggtcgata tcctcctgaa cgctgatgtc 3750661 cccttttaca aagcgaaaac ggctgttttg ctttaatttt tccatttcct ccgggtggct 3750721 ggcgtacgtc agtttatcta aaacggtaat gcgcgcatcc gtttccctca gcatgagctt 3750781 tgtaaacgtg agcccgatga agccggcccc gcctgtaatt aaatatgatt ttgccatcac 3750841 ttttcgtcct gtcctttccg taaagcctgg tgtacaagct gggaagcgag ataaagcgat 3750901 tcgtgagttc cggcatctac ccaccagcct gataacacat catacgtaag ctggctgttt 3750961 tcgatgtata gattattcac atcggtgatt tccagctcgc cgcgctttga tggtgatatt 3751021 tgttcaatat atgaaaacac ctctgcatca tacatataaa tgccggtaac acaaaggttg 3751081 gtcggtggct gttcgggctt ttcgatgatg gaacgaatcc gcttgttttt ctcatcaatc 3751141 tcagcaatcc cgaaacgttc cgggtcatca acttctttca gaagcacttt tgctcctttc 3751201 ccctgctgtt caaagcgttc tgtataaggc tttaatgaat cttcaaatat attatcacct 3751261 aataataaaa tgaaagactc ttttttcgta aagcgctttg cataagacag cccatccgaa 3751321 atgcccgatg ctgccggctg tacttgataa gtgatagtaa cgccaagctc ttccccgttc 3751381 ccaagcagtt tgtaaaattg cggcatatgc tccttttggc tgatgagtaa aatgtctttt 3751441 attccggctt cctgcagctt cataatcgac cagtatatca tcggatacgg gcctacagga 3751501 agcaaatgct tgttgacggc tttcgttaag ggcataaggc gtgagccgtt tcctccggct 3751561 aaaataacac ctttcacatt aacacttcct tacatgcatt tttatatctc ttgttcatat 3751621 aaatcttgaa gaatagctgt tacccgtata atgcctttgc catccacgag cggccttcct 3751681 cccttgtgca aagaaaggcg aagaggatag ctgctcataa tgcgtgacat ctgatagatg 3751741 agtgtttcat ccggtacaag ctcacccaat ccaagatcaa gagcggcgcc ttggtcagca 3751801 aatgttttgg ctgtagccgt ttgatgctca acctgagaaa gaacaaggca cggcacgccg 3751861 atgcaaatgg cttcatatag agagatgccg ccagcgacaa tggctgcgtc cgcttgtttc 3751921 atcaaacctg ccatatcatt tgtctgttcg atcatcttgt actgcggctt cttttcgatc 3751981 cgccttcgga ctgcctcttg atgcggtgaa gcgctcccca tcacaaacat catgtttttg 3752041 tcttttatgt cggggacttg atcagcggca gccagcactt taaaaataag ctgcttcgga 3752101 tcacttcctc ctaatgcaac aaggatattg cggcagtctt tcttaagtgt gtaatcctct 3752161 cttgcggcct gaaaggcggg gtgaagaata agatagtccg gaccttcata gatgcgtgtg 3752221 tttccctgaa cgtacaccct gcttctgatg tcaccgtaaa ttccgttaat gactgcgtca 3752281 ctatattgaa tcgatttacc gtttttctct tcaaaaagaa caattttcgc atctgtctcc 3752341 gtctttattt tctttaacag ctctgcaggc gcgcctagaa tatcaaacaa aagcaaatca 3752401 agcttcttgc tttttatttc ccggagaata aattcgtgct gctgcagctc cggctttacg 3752461 atgacctgcc aatgctcttc atgaagaaac gcttcagaat cctgattcgt ataaaacgta 3752521 atcaagcatc gctgtttgag cccctccgca agcctcttca tccggacaac atggcccatt 3752581 cccttttcat agccgccgtc tgcgaagatc ccaacatgca tggctagtca gcctctcgtt 3752641 cggttgccgc atcggggttc cggttcagaa gggtgataag ctctgaggcg gatacatcgg 3752701 ggcgctcgcc tgctttttga tagagggcct ttatcgattc atagtcttcc tttgtatcaa 3752761 tggtcagccg atattgaggg gcgcgaaatc gttccggcgc ctctaaaaac tgaacacgat 3752821 aaagagctgg atgattcctt atatataacg tgacatgctc ctgatattga tcctccaaag 3752881 cctgaatacg gctgatgtca attaacaggt tggcgttgac cacttcgccg caaatcccta 3752941 atggggcatt caggatatac gtataatccg agccttgatc aaaatgcgcc tgaatcatta 3753001 catcgagcag ctcaggatcg acaaacggat tatcacctgt taaccggatg atgactgacg 3753061 gtttaacagc ttctatgacc ttcacaaacc tatcgaggac acgttcttcg ctcccgcgga 3753121 aaacacgaaa gccttgtttg atacagtgcg cctctaatat gtcgtcagtt tctttgtcag 3753181 acgtggcgat gacaagatta tcccgatcct tttggtaaaa cgcgctttgc cggacacggt 3753241 gaacgagaat atcaagtaaa cgattcgatc cgagcggccg aagcactttt cccggaagcc 3753301 ttgttgaacc cattcttgct tgaatgataa agagaatatc attcatgaaa cgggctgtcc 3753361 ttcagtaaaa tgtcatccca gacaatgcct gtgtcggctg gaatgtctct tacagcccga 3753421 acaccgctgg tcagcagttc aaaaaatctc gggtgcagcc cctgcggctt ttgtccgggc 3753481 cgaagcactg cgatattgtc ttcactaaag gcttcacctt tttgaatcgg agctgttgta 3753541 aaaatgcctc tgtatgcaaa gtttctgatt tctccttcga tggcggtcgt tgttttgtat 3753601 gaactgccaa gcagtttttc agagaccggc tttgtgatcc cctgtttcag ctcagcttcc 3753661 gttttcctga tgccatcgac catttctttc aattcatccg gatttaatgc aaacgagtgg 3753721 tcagcacccg gcagattttt atcgatcgta aaatgctttt ctatcagttt tgctccgagc 3753781 cgaaccgcgg cacacggcgc ttctgtcgga tgctcgctat gatcggagaa gccgattacc 3753841 gcctcaggaa aagcggcggc aagcatcgga atgacgctga ggttgctgta ctccggcggt 3753901 gctgggtatt tcgccacaca atgcattatg gcaatttgat tgtttccctc tgccctgatg 3753961 gtgcgccaag cttcgtgaac atcagagatt tcagctccgg ctgtcgagaa aatcatcggc 3754021 ctgttcagcc gggcgacata tttaagcagc gggagatggt taatttcata ggatgcgatt 3754081 ttaaaagcgc tcggcgaggt agactgaagc agatcagctg acccctcgtc acataccgta 3754141 cttaaaaaga tcacctgctt ttcgcggcag taatccaata gcggtaaaat ccactcagca 3754201 ggcatttcca tagattgaac caaagaaaaa atagagacgt ccttgcccgc tgccgtcttg 3754261 tacaaaccag gatctttctg gtacatccta tcagcttgga acatttgaaa tttcacggca 3754321 tccgctcccg cttccgccgc ggcgtctatc agcgcaaaag cctgatcaag cttcccgtca 3754381 tgattaatcc ccgcctcagc aataataaaa acaggagcgt ctttgcctac agttttattc 3754441 gcgatctgaa acgctgccat tatttcgcct ccttgcccgg ccaaatatga taatagtaat 3754501 acgattgttc agcggtgaag cccattcgtt cataaaggcg gatcgccctt acattgtgaa 3754561 gctgcgtccc cgctgttacc gttctatgct tctgggtctc cggttgttct atgagattcg 3754621 ccaataaatg aaacgcaata cgtttccctt caaatcccgg ctttacagcc atcaaatcga 3754681 gaatgcactc atcatctctt gataagccct gaagatagcc gatgacctcg ccattgtgtt 3754741 tagcgacaat attgaccgcc gcccttccat tcagattgtt tcgtgtccac tcctgaaata 3754801 tttcgtttgc tgcatcgcgg ctgagatgag gatcctgaaa atatctgctt tttgtaaacg 3754861 agtctcgggc cagctcacat atcgcttctg tgtctccggg ctcaggcggg cccagttcaa 3754921 aaaatggcgg tgttttgtca taaaaagacg gaggcatcgc cagcttcagc aaactcccga 3754981 caaagtaaga ggatggctgc tgttgtatca catgcgcggc tccgatatct tcagccggaa 3755041 cacggacaaa gataaaatcc gtttcatcca tttggcgtac agtataaaaa gcttcaaaca 3755101 gcctctttag ctgcccggta ctatttgccg caagaagttt gacgttcatg actttcttct 3755161 gaagcacctt gctttcccac aaagaatctt cgtaaagcaa tacgccttgg agcctgctgt 3755221 tttcaaaaag gccgagggaa aattgatacg gaacatccaa tgtaagcttt ctgctttgga 3755281 gaaattcctc aattgcctct ttggagacat tttcttttac cgtatacact taatcagccc 3755341 cttttacgat atcccgcaca gcttcaatga catcatctac atcatcgtca gacattgatg 3755401 gatagagcgg gagagaaagg gttcgtttat agtaattcat ggcattcgga aagtccgctt 3755461 ccttatatcc aaattgcttt tgataatacg gatgaatgtg tactggaata aaatgaacgc 3755521 tagtgccgat attgtattca tcctttaaag ccgtaatcat ttcgctgcgc gtaaccccgg 3755581 cctttttttc atcaacttgc agaacatata gatgccaggc gtgcctgccg tcatcatgga 3755641 caaacggcgt gatcagccca ggaatctgct gaaaagcggt ttgatagcgg ccggcaatct 3755701 cttctctccg tttctgcata tcatccagcc gtttcagctg atgaagtccg agggccgcct 3755761 gcaaatcaaa catattcatc ttatagccgg gcgattcgac ttcatagtac cagctgccat 3755821 ttgaagaata acggttccat gcggctttac tcatgccgtg aaggcttagc acccgtatct 3755881 tatcggcaag ctcctcatca tcagtcgtca gcatgccgcc ttcccctgtc gcgaggtttt 3755941 tggtggcgta aaagctgaat gccgttgcat ccccgataga accgatcatt ctttgcttat 3756001 aagtcgtata taccgcatgt gccgcatcct ccagcacgaa taaaccatga ttttgggcaa 3756061 cagccaatat tgcatccata tcgcaggact gcccgccaaa gtggacgggc acaactgctt 3756121 tcgttcgcgg tgtgacggcc gcctcaagct ttaccgggtc aatattgagc gtgttttcgt 3756181 caatatccgc aaacacaggc gtcgctcccg tatgaataat cgtattggcg gtcgagctga 3756241 acgtaagcgg agaggtaatg acctcgtccc cgggcccaat cccttttgct ttcaaagcca 3756301 aaaataaagc tgcggtacat gaattcaccg ccacggcgtg cttcgccccg acaaacgcgg 3756361 caaactcttt ttcaaactgc tgaaccttcg ggcctttaga gagccatccc gattcaagcg 3756421 tttctgtaac ctcctgaatt tcttccttac cgattaacgg caatgagtaa gggagaaaat 3756481 gatttctctt ttgcaccatt tctttgcgct cctatcattt tattcagtat cttcccgcct 3756541 gtaatcaacc cctgttttgg ctttcagttc cgcaaataaa gcatttgttg attctgccac 3756601 cggataatta gccgctatga atgccaggcg cgcctcttct gctttttgat gcacgtcggg 3756661 acttcgaaga acctcaacca aggtgtgcgc cagttcatcc ggctggtcaa acataaaatc 3756721 gccaagagac tcataatacg gatacgagcg atttccggac gattttccta tcagcacagg 3756781 cttttgaaac agcatggctt caagaccgac tgtcgaggtt tgcgtcactg cggcatcaac 3756841 atacggcagc aaatcataaa gctccagctc ctttttgatg actctgcatg cttgatgttt 3756901 tttcgccgcc tcgtgataca gatcaagctt gttttttccg atttcccacg ggtggggttt 3756961 gataatgatt tgcagctgct tctgatcaga aagcccctgc agcacaccgg aataaaagtc 3757021 ttctgaaaag ggctgagtgg caatgagcac aattttttta gtcggctgaa aagcaagttt 3757081 tcgatagaat atggacatat ccataggcgt tctgttaaaa atctgatcga agcggggatg 3757141 tcccgttacg agaatctgct cgggtttaca gccttttcgt atgaaccact ctgcttcata 3757201 cgcaccaaaa acagcttgat aggttgtaaa aacaggaatg aaggcttcat ctcccatcaa 3757261 tgcgccatgc tgaagacaaa tgctgacggc cccttttctt tgacacatga gagcgagcac 3757321 cctgctgtaa atgtcttctg ccgttccgac aataacagct gaaatctttt cctgttcaaa 3757381 cagcgcatca actgtatcaa tggcctctat aaataaagga atatctttga aaagccggtc 3757441 gcgaaacgct tgatcaccaa atgccgggtg atcatcataa ggggcgagaa gcgaacaggc 3757501 tgtttcgaga tactgcttcg aatcgccttt ttggcatgaa tccgcaatct cccgcttgct 3757561 aattacaggc agatcacaat aatgcggcaa actccatctg gccaaaacag ccgttttttc 3757621 aggatcaaat tgatagtaat tttcgtttga aaaacgcagg taatcaaagt gcaaaatgac 3757681 tttcccttta acaggttcgt catttgtttt aacgatgttt tggattcttt cttcaaaaaa 3757741 cggctgaatc tgtccctcat cgatatgctg atccaccgat ccgaataatt ccggttcttc 3757801 ttccatcatc accctcagtt cagggctgat gtattgataa aaattactga taagcccaag 3757861 cggaatccct ttgtagcgaa gtttgtcaaa aagctccacg tacttccggt acagcaccca 3757921 ataattgctt aaataggccg acaagctctc accccattcc aagctttttt aatgattcac 3757981 gcagctctcg gcaatttcgc tgcggaggaa ggttcctgac aaattcattt ttttctaatt 3758041 caaacagctg aaagtgaatc gattggtcgg taatataatt caggtccagc tcctcatcca 3758101 gtgggtaaaa cggataaaaa tgattgactc tccaaaagaa ccgggcatct cctatacggt 3758161 aaaacgccgg gctttcatcc caataggagc caaacttctc ctttaccttc tcaagcaccg 3758221 aatacctgtg catcaccgag caatgatcaa ttgcgcacgg cgcgttccat gtcacttgag 3758281 cggcaggcct gacagtttct tttacaatgt cacgattctc gtttaaatga taggttttgg 3758341 aggctgagta aatcacagcc ttttcaggat gggtatcgag ctcccgcacc attttcagga 3758401 ggcggtccgg catatagatg ttgtcatccg tcgcataggt gatatattca ccctccgcca 3758461 tctcaatcgc ctgattgatc agtgccgcgt atctcgtttt ttctgttctt tccttcactc 3758521 cagatatatc gctttgataa aaacgcactc ggttatcatt caaaaaagga cggattacat 3758581 tcagcgtctc ttcattggag ttgtcatcca taataaacaa ttcaaaatct gaaaacgttt 3758641 gtgagagtat gctagaaatg gactttgcca cataatcgct tttgttatag ctcgtcataa 3758701 tgactgatac tttaggcaaa tcctacacct ccttcttgga acttcacacc tgaaactatc 3758761 gttatcttat gttgcttatg ctcaagttgc gctagggata caaaccaata tgcgaaaagt 3758821 ttgtgtatgt ttctgaaaaa cagcggctgc ccagagcgaa atctgatcgg tccgctgttc 3758881 tttttcagca taatccaagc atcagcctca taaggtgaaa gagataaaaa tcgcaccagc 3758941 gactaagatc gttttccatc ggaggtgagt catcgcggag cgttcaccta tacatccaga 3759001 acatgttttg aatggttttc ataaaaagga ggaacgatat gaaaccgaaa aaaaatcaat 3759061 atcagcaaat gcaggcattt gataatatgc aggggtatca gcctcagttt ggcgccaacc 3759121 cgtacccgca gcaaggccaa ggctcacaaa tgcagacaat ggggatgcag ccaatgatgc 3759181 caatgcagca gggacagcaa ggacaacaag gacagcaggg atttggattc ccgggccagc 3759241 agcagggcgg cggttttcaa attccatcgg ggcctacacc gtcaggaccg ggccaaagcg 3759301 ttcccggcat gctgcctgtt gaggaatctt acatcgagaa tattttgcgc ctgaatcggg 3759361 gaaaaacggc caccatttat atgacatttg aaaacagcaa ggaatggggc tcgaagattt 3759421 ttcgcggcgt catcgaagct gcgggccggg atcacattat tatcagcgac ccgaaatcag 3759481 gaacacgcta cctgctcctg acaatctacc tcgattacat tacatttgat gaagaaattg 3759541 cttatacgta tccatattcc atggcgtcct attcgccaag ataagaaaaa agccaatcac 3759601 tcatatgatg aggattggct tttttgttta tagatatttg acggctgcga caacgatcat 3759661 aatccaagaa ataataaacg ccacaccgcc gagcggggtg atcgctccaa gaatggagat 3759721 ttgcgtcaca cttagaatat ataagcttcc ggaaaacagc acaattcccg caaacatcag 3759781 ccagccggct gtcgtgacac tgcctatgcc ggataattta tcagccagaa acgcgacaac 3759841 gaataaccca agggcgtgat acatatgata ctgcacgcct gtgtgccaaa cctgaagata 3759901 cttatcaggt attttccctt ctaatccgtg agcgccgaat gctccgagtc ccacggcaag 3759961 cagggcgtta atggccccta atatgataaa aactttcatc tatctctccc gccttttcgt 3760021 taaactcata tcatttatct tatcgcacct gcaccaaaat tcaatgtttg ttctccgttg 3760081 acacgagatt gtcggatttt ctcctgcgcc aaagctggaa ctggtcagct gctattgcag 3760141 caagcgtccc taatacgagc ccgttgctta atagagaaat aaataccgga tgcaatccct 3760201 ttaacgcagt ttcaggaaca aacatgatac cgacccctgt cagcagtgag ataccgatga 3760261 tagacctcac cctttttgat tcttctttct catatgaatc aaattcggca aaggccagac 3760321 cgcccattgc ggagaacaca acaaaattca ccgcaaatcc aacgggtgac ggcaggctcg 3760381 caaacgtatt cataaaaaac gggatcacgc tgatcacgat aaccagaata ctgccgagca 3760441 taaacggttt tttagaaggc atcttggtcg tttcaataaa acctgcggct cccgaaatcg 3760501 gaacaggcgc aatagctccc gtcaaaccgc taagcagatg gctgaatgaa gctgcaaaac 3760561 cggcatggcg ttcatgatgc tttccatcag gctgtttgct gaattttttc atggcgatgt 3760621 ccacgacctt catgctcgcc agcatattca cgatcagcaa gatggtaata aaaatagaag 3760681 tgatgatcag gccgctgtta aataacgggg tcccaaaagg aaacagggaa ggcagctgaa 3760741 acagccggtc cggcatttca atcggctttg cggctccggc agccgcaaac agcacccacc 3760801 cgccgaacaa ggctaataaa atagaatatt gcttaaaaaa catgatgttc gaatttgtca 3760861 ttataaaagc ggcagcgatc acaacaagcg ccaggccaaa tacaagaccg tccaccccgt 3760921 cctgtcgata accgattccg agaattcctt ttataatggg ctgactcagc tgcatgacaa 3760981 gaagcaataa atagacgccc gttacaaccg gagtaaacaa ttttgcaagt ctgtcaatga 3761041 ccttgaaaac acttaacaaa aagaaacata cagcgcttac aagaagagct ccctgcaaac 3761101 cccgcagtgt gtctccatat gtcgcaaaca cagttcccgt cagccctgcg taaatcgtat 3761161 acactcccca ccacaagccg gctgggcttt cattgatcgg cagtctgtgg cctttcaaac 3761221 actgaatgac ggcggcaatt cccagtacaa aaaaagtgct ttgaatcaat cttgcagaat 3761281 ctgagtgatc cagatgaaac gactgggcaa ccgccaccgg aacaacaatc gccgcagcaa 3761341 taataaacgc tgtccattgc agcgcgccaa gaaccaattt cacgtaagct caacctctct 3761401 ctttaaaaat caaataaaga ctctccgttt ccatcctctt cctgcttctc tttttcttgc 3761461 tttcgatatt tgtttaatcc cgcgctcccc atcatttttt ccatcatcag ctggtctgtc 3761521 gatggcggcg cggcgggact tggcgtaacg ctcggctgta tgcggggcgc gctcgcgttc 3761581 tccggctgat caagcacgac atcacacaga gaacggacaa ccgctacata acgcttcagc 3761641 tcctcatccc gttcagccgt ttttgctttt tttagctctt cttccatctt ttgaatcaaa 3761701 gcagatatat gaatgttcat gaagcaccct ccaaaaaaat aaatgttgtc ttcctgcatt 3761761 ttatcaaatt cctgctgaaa acgcagatat gagtttgtta ttttttctga caaaccttgc 3761821 gcgattgaca agcagaagag atttttcaca taataaatca ccatacctta caaaaaggag 3761881 aaacggaatg aacagcatcc cctctatcat cagcaagcat aaagcctatt ttgcggcggg 3761941 acatacgaga ccgcttgaat cgagactgaa cattttgcga aagctgaaac aagccgtcag 3762001 aactcatgaa gccgatctca tagccgctct ctaccaggat ctccataaat ccgagcaaga 3762061 agcatactca acagaaatcg gaatcgtctt ggaggaaatc agctttgtca tgaaacggct 3762121 gagaaaatgg tccaagccga aacgagtcaa aacgccgttg actcatctag gctccaaaag 3762181 catcatcatc cctgagccgt atggaaccgt tttggtgatt gcgccttgga actatccctt 3762241 gcagctggcg ctttctccgt tgattggcgc cattgcggcg gggaacacgg tcgttctcaa 3762301 gccatcagaa tatacgccgg ctgtttctgc tattctttcc aaactcatca gcagcgtttt 3762361 tccaactgat tatgtcgcta tggcagaagg cgggcccgat gtcagcacag cattattaca 3762421 gcagcccttt gactacattt tctttaccgg cagtgtagct gtaggaaaaa tcgtcatgga 3762481 ggccgccgcc aaacaattaa ttcccgtaac cttggagctc ggcggcaaaa gtccctgcat 3762541 cgtccataaa gatgctgaca ttcagcttgc cgccaaacgc atcgtcttcg ggaaatttac 3762601 aaatgcggga caaacctgca tcgcaccgga ttatttattt gtccacgagg acatcaaaac 3762661 gaagctcaca gaagaaatga agcgtgcgat cagagaattt tacggccctc agccggaacg 3762721 gaatccacag tacggcaaaa tcgtcagtga gcgccactat cagcggctgc tcagctttct 3762781 gaatgatggc atcccgctca caggcggaca atctgatccc aatcatcaca aaattgcgcc 3762841 gaccattctc gaacaagtga gagatgactc tccagtgatg caggaggaga ttttcgggcc 3762901 gattcttccg ctctttacat accgcaatat cggggaagtc attgagaaag tccaatcgcg 3762961 ccctaagccg ctcgccctgt atctcttcac cacaaacaaa gaaattgagc gcgctgtttt 3763021 aggaaatctg tcgtttggcg ggggctgtgt caatgatacg ttaatgcatg ttgcgacgcc 3763081 gtatttgcca ttcggcggcg tcggggaaag cggcatcggc agctatcacg ggtttgacag 3763141 ttttaacaca ttcacgcaca aaaaaagcgt cgtcaaacaa acgaaccgtt tcgacttcgc 3763201 atttcgttat ccttcctcca aaaacgggct gcgaatgatt cgaaaaatac tcaaataaaa 3763261 aagcgcagat cacctgcgct ttttacaaat ccttaataca ccaatcaatc ggcgcctctc 3763321 ccattttctc caaataggca ttcgcccggg aaaacggtct gctcccgaaa aatccgtttc 3763381 tcgcagaaaa cgggctggga tgcgtcgatt caatgataaa atgcttggag gtgtcgatcc 3763441 gttctttttt catttgagca tgccgtcccc acaaaataaa gataaccggc cgctctcttt 3763501 cactcagcac gtcaataatt cggtccgtca gtcgctccca gccttttccc ttatgggaat 3763561 tcgcctgtcc gcgccttact gtcagcacag tattcagcaa aagaacgcct tgctttgccc 3763621 agctcacaag cgacccgtga ttcgggatgc tgcacccgat gtcctgctgc agctcaagaa 3763681 agatattttt taacgaaggc ggctgcttta caccgggctt gacagagaag cttaaacctt 3763741 gagcctgtcc cggcccgtga tacggatctt gacccaaaat gacgaccttg acatcatcat 3763801 atgatgtata atgcagcgcg ttgaaaatat cccggctgtc cggataaatc gtttgctccg 3763861 cgtattccct cttcagcatc tctctgagct cttgataata cggtttctca aactcttcct 3763921 ttagctgatt ccaccagctg tcttgtaaaa gctgtttcaa gattcaggcc tccttacgaa 3763981 cgatgaagtc tggaatagac aggctcgcca tcccaaacca tttcactttt tgcttcccgc 3764041 ctcttcatct caggctcttc aagcaggacg gcaaagtttt tcgtcggcag ctccccgagt 3764101 ccgtgctttt cacttaaacg atccaaatat tgcttccgct tggcgccaag gtcagcagac 3764161 tgattgtctc ccgcgtcact gaaggcataa atcacgctgg cgcaagggac acgcttcacc 3764221 cggtaatcct tggccgcgcg caaataaaaa tcccagtccc agtaattgtg cacatcagca 3764281 tcgaaatacc cgatttcatc atgcagaaaa cgtctgtaca tgctgcccga cggcacgtat 3764341 gtagaaaaca ctctcatatc ctcatagtca gcggtataag caaacaattt ccgtgacact 3764401 ggataccttg ttccgttttt ctcttcaaac gaaactattt ccgcatcaga atgaacgaag 3764461 tctgccgttt ctatttcctt tgccattttc tcgatatgcc ctggcgtaaa gaaatcatcg 3764521 tcatcacaca gcataatgca atccccagac gcctctttta caccggcatt tctcgcagcc 3764581 acatgccccg agttcttttc taaattgatg acagcaatcg gcagctccgg ataaagtgct 3764641 ttgaccggca cgaccgattc cccggcatca ttcacaataa taatttcata cggcatcaag 3764701 gtctggcggg aaatcgactc caaaagctca cacaaagccg gaatccgatt ataggtcaca 3764761 attacgatag aaatcttcat gatgctctcc ttctcatttt catagtcatg tactattaaa 3764821 acatatattg gacgggagat cagtgggaat atcctactga aacggcatac tacaatgata 3764881 gaaacagcaa agtggctccg atcagaagca ccatgatcag catcagatct ccaaagacat 3764941 gaaagatatc tttcatgcgg acgccattcg gaaggataag acgccacagc ttagattgat 3765001 agaccggcag cagcaccagt gcataagaaa gacacaaaaa tgtaaaagcc ggcggcacaa 3765061 aagcacagcc tgcatcgtcc caattcatca tgatgtcttt catactagat ccatccaata 3765121 aaaacaaaga tatcatgagg gctagcaaca caaaggaccc caattgaacc tcaaacaggc 3765181 gcattttctg gttatatgca aatcggaccg cccaaaacca gacataagca tatgaacata 3765241 gcagcgtaag aatggcacct gctgtaaaga cgacatcagg cagccgatca agcagaaaaa 3765301 caaaaggcaa gctggctgcc atagccaaga gcatgcagcc accagtaaac aaaaatactg 3765361 ccccatgagc tacaaaacca tataaacaag agctaatcct cacgacatac acctccttta 3765421 catagaaatt ctatgtatat acctaaaaaa tcagacaagc tgacgcctgc caatataaca 3765481 gcccattcgg ccaaataacg gaaataacag cgttgcaaaa gcacaagttc caacaaacca 3765541 aggtgtcaac aaggattgaa acagcgcagc aggaattaca ttgaatagaa aaacaagcat 3765601 aaaaatgacg tttggcacca ttgagatcag aatcgtatgt agaacaagct tttctccgcg 3765661 ttttccaaac tccttcacgc cttgataccc aatcagcacc cagtagatca tatatgcagc 3765721 taagatcagc caaacagaaa cagaaatgcc tttccatact gcttgaacaa acggtgattc 3765781 aagccataca tgcattattg taatcgcaat gccgacagcg aatagggcac tgttacagaa 3765841 aagatggaac atcaaaaacg cacgaaacgt tactggctgt attttcttaa acgaagaaac 3765901 aatgtcagtt ggtgttccaa acgcctgcaa taaagtctgc atagcttcct cctcactctt 3765961 tccttcctga aaagagcgaa acagatgatg ttcaatatgg ctctcaatct cttctatcat 3766021 cgcctcaccc tcaggaagcc ctttaagccc gcttttgatt tcggatacat atgtttcttt 3766081 atccattttg tccgctccac ttcagtattc ggtccatcat ggctgaaaat acgctccatt 3766141 ccttcgtgcg ttccgccagc acttctttgc cctcgtctgt aatccggtaa tatttgcggt 3766201 ccggtccttt ctcctgcttc tcccagtagg aagaaatata cccttggcgt tcaagcttgt 3766261 gaagagaagg atacaaggtc ccttctttca tctgcagttc atttccgctg cggcttccca 3766321 tttcttttac aagctcatag ccgtacatcg gccgctcgtt cagaagcgtc aataccaata 3766381 taaccgtgct tcccttaacc agctcacgat ttaacatctc aaaaccccta cctagttttc 3766441 ttatgtagca ttttacgaaa gcccgttgag attgtcaaat gattcctata gatcttctat 3766501 attgtgatac agagaaaatc taactataat gaaagacaaa acatgatgga ggttcaagac 3766561 atgtctatgc ataaagcact caccattgcc ggctcagatt ccagcggcgg tgctgggatt 3766621 caagctgatt taaaaacatt tcaagaaaaa aacgtatacg ggatgaccgc cttaacggtg 3766681 atcgttgcga tggacccaaa caacagctgg aaccatcagg tattcccgat cgatactgat 3766741 acaatccgcg cccagcttgc aacaattacg gacggcatcg gcgtggacgc catgaaaaca 3766801 ggaatgctgc caaccgttga cattatcgag cttgcggcaa aaacgatcaa agaaaaacaa 3766861 ttaaaaaatg tggtaattga cccggttatg gtttgcaaag gtgctaatga agtcctttat 3766921 ccggagcacg cccaagccct gcgtgagcaa ttggctccgc tagccactgt cattacgcca 3766981 aacttgtttg aagccagcca gctcagcggc atggatgaac taaaaacagt tgacgatatg 3767041 atcgaagccg cgaaaaaaat tcacgcactc ggcgctcaat atgtcgtcat tacaggcgga 3767101 ggcaaactca aacacgagaa agccgttgat gttctctatg acggagaaac agcggaagtc 3767161 cttgaaagcg aaatgatcga tacgccttat acacatggcg caggctgtac attctcagca 3767221 gccgtgacag cggagcttgc caaaggtgcg gaagtcaaag aagccattta cgcagcgaaa 3767281 gaattcatca cagcggccat taaagaatcc ttcccgctaa accagtatgt tggtcctacg 3767341 aagcattctg cactgcgcct gaatcaacaa tcataaaaaa aggggctgcc ttacagagag 3767401 gcagcccttt ttaaatcacc gaagactttt cacagaaaaa actgccgatc ccatcggcag 3767461 cctgtttatt tgatttttaa attgtttgca gatttcctca aaaatgtttc tatcgactga 3767521 acaaaaagtg catattcctt catttgttca tatgcccgcg tgagaatttc cgccgtttca 3767581 ctgtgcggcg ttgttccgcc aagcattttt ttcagctgaa gcagcacatc cttatattct 3767641 tctcgcttat cttcaacttg gttagcagcc ttttccaaac attccggtgt tatcttctgt 3767701 tcatgtatat tcaagaaaac aactcctttt acagaaaaaa atagtaggtt atcgttgaag 3767761 aatagcacag atggctcaga tttcacataa gaaaatagaa ggattttcta cataagtgtc 3767821 caaattccga cattcatttc agatttcccg gtcgcactgg ctgttacttc atgatttccc 3767881 gggaaaggaa aatatcttgc actcaagacc tcttctccgt tattgataaa gatttccaca 3767941 gatgacgcgt cgagaaacat gtgtacggta tgcaaatcct tgatgcggca atgtctcgct 3768001 tctgttcttt ttccgtcaaa gctctttcgt tccagcgtaa caatcccctc gtctttatgg 3768061 aaggaaaacg tagccgttcc gcggatactg attgaaaagc cagactccgt atgaatgtct 3768121 tccagtagaa tctcagttct ttcaggtttt tccactggaa gcgcaccaga tgatccatgc 3768181 atgttgatgt gtattttttt ctcatttctg cgcatggctt ttagctcagg cagcggctgc 3768241 tgaatcagct tctgtcctga aagcgtcagc tgtctcggca gcgtcatgca gtgaatccag 3768301 tggcagtcaa tggtcggatg ggacccttca tcctgatcag gcaccgccat ccatgcaaat 3768361 aaaatccgcc ttccctgatc gtcttcaagt gtttgcggcg cgtaaaaatc aaaaccttga 3768421 tcaagctccg taaattcacc atgcttcagt tcaggcttgt tataatcgag gcggccgaca 3768481 aaataacctg attgatatac gttctgataa cggaaaccgt cagcctcaag cccttgaggc 3768541 gaaacaatca gcacatccga tccttgaagg gaaaacaaat cagggcattc ccacatgtat 3768601 ccaaaatcgt ccagcccgtt gaagcccgcg ccggttatcg ggccaagaaa tctccactct 3768661 gtcaggttat cagaagcaaa caacacagcc tgccctttca aattctctgt ttgcgcacca 3768721 atcaccatat accatgtgcc ttcatgctcc cataccttcg gatcgcgaaa atgcgccgta 3768781 tatccttccg gaaggcgggc gacgacaccc tttttctcaa aggacagccc gtcgtcagaa 3768841 acagcaaggc attgatacgt ttcccgattt ccatcctgat ccctgacatt tcctgtgtaa 3768901 aaaagataga gccgatcgtc tttcgtgaca gcgctgcccg agtagcagcc gtttttatca 3768961 aaccaatcac tcggagccag cgcaatctct tcccgcttcc aattcacaac atcctgtgtc 3769021 gtataatgcc cccaaaattt tgcgccgtgc cccgtctgaa acggctgcca ctgaaagaat 3769081 acatgatagc tgcccttcca ataaatcacg ccattcgggt cattcagcag cccaaccggc 3769141 ggcatgatat gaaaatgctg gcggtgcgga tcgctgttag cgatgggctc ttttttctcc 3769201 acttcttcat aagcccggcg acgaagctcc tggtcatgtg ctgtcatttt ttcctctcct 3769261 catcctcatt aatcttcatg acaaatgctg caatgaacgc tgacactgcc gcaatcgcca 3769321 tgccaatcag atagtgaatc aagttgctga agccaaacgg agccgcaatg gcgatcatcg 3769381 gaattcccgt taacccgtaa gcgtttgcag ctacatgtgt aaagacgaca tatgccccac 3769441 ccaatgcgcc tccgatcatc gcggcgataa acggttttcg gtagcgcaga ttgactccga 3769501 atatgacggg ctcagtaatg ccgagaaaag cggaaaatgc tgccggaagc gcgatttctt 3769561 ttgtctttgc ctttttcgcc ataaagaaga cggcaagacc tgccccgccc tgtgcgacat 3769621 tcgccattga ccagatcggc agcaagtagt ttttgcctat atctgcaatt agccctgcct 3769681 caatcgcatg gaagctgtga tgaacgcctg tcagcacgat gagtgaatac gtgcccccga 3769741 aaatcagacc tgcgacaaaa ccggcatggt catatacata agttaaagca accgtaatgc 3769801 cggagccaag cgctctgcct agagggccaa tcgcgataaa agcaacaaac ccggtgacaa 3769861 tcacagtaac aaatggtgta acaagcaaat ccaccgcatg tggaaccact tttctcgtcc 3769921 atttctctac cttgctcatc acatacaccg caagcaggac agggataaca gttccctggt 3769981 agccgagaag agcgatatca aatccgaaaa gatgcatgta atcaggtgtc gcttccgcca 3770041 atccccatgg atttaaaaga ttcggatgaa tcatgattcc cccgatgacc gctcccaagt 3770101 atggattgct gccaaactct tttgaagcgc tgaccccgat tagaatcggc aagaaaatga 3770161 atgctgcact tgaaaacata tcaagcagct gcaaaagcgc agaatccttg ctcatccaat 3770221 gaaacgcatt gatcataccc agcaatccca ttaataggcc gctggctaca atagctggga 3770281 tgattggaac aaaaatatta gaaagcgttt tcgcaaatct cgcagcggga ttcagctttt 3770341 cttttgccgc atcctgatga ttgacgtgtt cttcacgctc gatatcagct tctttagaaa 3770401 aggcatcgaa tactttattc acaaggcctg ttccgaaaat gatctggtac tggccagagc 3770461 tgctgaaagc ccctttaacg ccatcaagct cttctacttg tgcttgatct atctttgatt 3770521 catctttcat cactaaacgc agtcttgttg cacaatgagc cgcgctgata atattttctt 3770581 tccctccgag aagctcaatg aggcgttttg cagtctcttt gtaatccatc tatttctccc 3770641 ccttttattt aaacaaaaaa gacctaaaat tcgccaacga ataaaggaca cagcgatcct 3770701 ttttcattta cgcaaatttt aggtcttgcc tgctttacca gtcacaatcc cgcttattca 3770761 gattaagaat acgctttcat cataaatcat gatagcgttt tcgtcaacta tttttttagt 3770821 taaatagttt gatataacat gtagacaaaa attcgtaaaa attaattgtg aaatacttca 3770881 caatatcgtg ctatactatg ctcaatcatg aaagaaagca ggaaaagaca atggaaactc 3770941 aagcattaca aaaggttgaa cagtatgctt tgaaaaaaca aaacatattc gcttcaagca 3771001 aaatccgtta tgtgcttcgg tccattttgg ccagtatatt tattggtttt ggcattacag 3771061 ccgcaagcaa aacaggcagc tatttcttta tggctgattc tccgtttgcc tttccggcag 3771121 ccgctgtcac tttcggggcc gctattctga tgattgctta cggaggcgga gatttattta 3771181 ccggcaacac cttttatttc acctataccg cgctccggaa aaaaatcagc tggcgcgaca 3771241 ccctatactt gtggatgtca agctatgccg gcaatttaat cggcgccatt ctgtttgcca 3771301 tcctgatcag cgcgacggga ctttttgagg agccttctgt tcattccttt ttgattcatt 3771361 tggcagagca caaaatggag ccgccggctt ccgaattgtt tttcagagga atgctgtgca 3771421 attggcttgt gtgcctcgcc tttttcattc caatgtctct caaaggggaa ggagcaaagc 3771481 tttttaccat gatgcttttc gttttctgct tctttatttc cggctttgaa cacagcattg 3771541 ccaatatgtg cacattcgcc atctcgcttt tgatcgagca ccctgataca gtgacactga 3771601 tgggagcagt cagaaactta atccccgtta cgctcggcaa tctgaccgcg ggaatagtta 3771661 tgatgggctg gatgtactac acactgaatc ctgatcaata aaaaaacttc cagagatcac 3771721 tccctgcaag tcaaagcggt tattccgaga gatcttgaag acgctggaca tgcagcgtga 3771781 tatagccggc ctcggattcc ggcaaatgta attgatattc atttttcaaa aactccgcca 3771841 gctccagcgc acattgatag gcgaatgaat actttttttg gatgaaataa agcatctcct 3771901 cgtccatacg atggagcgct tcatttgatt ccaaccggct gaccgcgtat cgcaaatgcg 3771961 tgacaaggcg ttgataggaa atgctgtttt catccacctt tcgattaaag tattgtttta 3772021 ttttctctat catttctttg atcatggtcg tatgcttcag cgctgaatac atgctctccg 3772081 catccatctt cgccgtatgg atgtgaaggg caatataacc cgcttcatct tcaggcagag 3772141 acacgcccaa tgtctctttt acatgtccga tcgcccacag gccgatctca tattcttttt 3772201 tatagagcgc ctttatctca tgcagcaatt tattctgcac aagcagccca ttttgaatcc 3772261 tttcgatcgc aaaggacaaa tggtcggaaa gcgcgatatg aatgtgatcg ctcagcggcg 3772321 ccgcgagctc tccttccgca tagctgatga tatcctcagc tatttctata tgctcctccg 3772381 gcagtgtttg caggatttgt ttgaactttt cattctcgtc gcgcacgaca aagatctttt 3772441 ccactttatt catagggatg agatcatttt tctttttttg aaaagcgatt cccggtccca 3772501 tcacgatttt ttcctgatca tcctctttta ttaaagccgc attgttgttt aatactttat 3772561 agattttcaa gaggttatct ctcccgccaa tttgcttttg actgggattt tacctccttt 3772621 tgaccgccat gtaaagatgc gggcccgctc tctcctgctt tggcgattcc ttgaaggctt 3772681 gcaaacatct tcttttataa agcgcggcgg ctttcgcttt ctgcttttct tcctcattca 3772741 cagccatccg ccattcataa aacgaaacga gtcctgcggc ctgcacagcc gcctttcttt 3772801 ggtatgtacg ctgagccgaa tagaccgcgg cagccgcagt ttttctgtcc ggcgtcaccc 3772861 agttcatcaa aaagaccatc cacacccgta aagatacaag caaacgtttc atagaaaaac 3772921 atccctccgc ttctttttgg caggcagcct ttttagcagc ccgttttctc agccgcagcc 3772981 cgcaagaaaa gacggccgat ttcttttctc gcaaactagc ggctctagca aaactcatga 3773041 ctctatgata gaccgtggaa agagaattct ttgtcacaat atgagtgaaa aaaccaacta 3773101 gtttttagaa gttttgttga aagctgaaag aattgaaatg aaaattggag aaccgctttg 3773161 aaaactttat acacaagtta tcccaaagat aagaacaact taatcacaag agatatccac 3773221 atgtccacaa actctatcta tattttgtat acgaacgtat attcctaact atatatatac 3773281 acaggtttat tcacttatac acagggttct gtgtataact ccttcgttat acacaaacaa 3773341 aatccaataa atggtccaaa tgacacaagg atttttttga attttcaaga aatatatact 3773401 agatctttca cattttttct aaatacaaag ggggaaacac attgaaaaag gggatcattc 3773461 gctttctgct tgtaagtttc gtcttatttt ttgcgttatc cacaggcatt acgggcgttc 3773521 aggcagctcc ggcttcttca aaaacgtcgg ctgatctgga aaaagccgag gtattcggtg 3773581 atatcgatat gacgacaagc aaaaaaacaa ccgttatagt ggaattaaaa gaaaaatcct 3773641 tggcagaagc gaaggaagcg ggagaaagcc aatcgaaaag caagctgaaa accgctcgca 3773701 ccaaagcaaa aaacaaagca atcaaagcag tgaaaaacgg aaaagtaaac cgggaatatg 3773761 agcaggtatt ctcaggcttc tctatgaagc ttccagctaa tgagattcca aaacttctag 3773821 cggtaaaaga cgttaaggca gtgtacccga acgtcacata taaaacagac aatatgaagg 3773881 ataaagacgt cacaatctcc gaagacgccg tatctccgca aatggatgac agtgcgcctt 3773941 atatcggagc aaacgatgca tgggatttag gctacacagg aaaaggcatc aaggtggcga 3774001 ttattgacac tggggttgaa tacaatcacc cagatctgaa gaaaaacttt ggacaatata 3774061 aaggatacga ttttgtggac aatgattacg atccaaaaga aacaccaacc ggcgatccga 3774121 ggggcgaggc aactgaccat ggcacacacg tagccggaac tgtggctgca aacggaacga 3774181 ttaaaggcgt agcgcctgat gccacacttc ttgcttatcg tgtgttaggg cctggcggaa 3774241 gcggcacaac ggaaaacgtc atcgcgggcg tggaacgtgc agtgcaggac ggggcagatg 3774301 tgatgaacct gtctctcgga aactctttaa acaacccgga ctgggcgaca agcacagcgc 3774361 ttgactgggc catgtcagaa ggcgttgtcg ctgttacctc aaacggcaac agcggaccga 3774421 acggctggac agtcggatcg ccgggcacat caagagaagc gatttctgtc ggtgcgactc 3774481 agctgccgct caatgaatac gccgtcactt tcggctccta ctcttcagca aaagtgatgg 3774541 gctacaacaa agaggacgac gtcaaagcgc tcaataacaa agaagttgag cttgtcgaag 3774601 cgggaatcgg cgaagcaaag gattttgaag ggaaagacct gacaggcaaa gtcgccgttg 3774661 tcaaacgagg cagcattgca tttgtggata aagcggataa cgctaaaaaa gccggtgcaa 3774721 tcggcatggt tgtgtataac aacctctctg gagaaattga agccaatgtg ccaggcatgt 3774781 ctgtcccaac gattaagctt tcattagaag acggcgaaaa actcgtcagc gccctgaaag 3774841 ctggtgagac aaaaacaaca ttcaagttga cggtctcaaa agcgctcggt gaacaagtcg 3774901 ctgatttctc atcacgcggc cctgttatgg atacgtggat gattaagcct gatatttccg 3774961 cgccaggggt caatatcgtg agcacgatcc caacacacga tcctgaccat ccatacggct 3775021 acggatcaaa acaaggaaca agcatggcat cgcctcatat tgccggagcg gttgccgtta 3775081 ttaaacaagc caaaccaaag tggagcgttg aacagattaa agccgccatc atgaataccg 3775141 ctgtcacttt aaaggatagc gatggggaag tatatccgca taacgctcaa ggcgcaggca 3775201 gcgcaagaat tatgaacgca atcaaagccg attcgctcgt ctcacctgga agctattcat 3775261 acggcacgtt cttgaaggaa aacggaaacg aaacaaaaaa tgaaacgttt acgattgaaa 3775321 atcaatcttc cattagaaag tcatacacac ttgaatactc atttaatggc agcggcattt 3775381 ccacatccgg cacaagccgt gttgtgattc cggcacatca aaccgggaaa gccactgcaa 3775441 aagtaaaggt caatacgaag aaaacaaaag ctggcaccta tgaaggaacg gttatcgtca 3775501 gagaaggcgg aaaaacggtc gctaaggtac ctacattgct gattgtgaaa gagcccgatt 3775561 atccgagagt cacatctgtc tctgtcagcg aagggtctgt acaaggtacc tatcaaattg 3775621 aaacctacct tcctgcggga gcggaagagc tggcgttcct cgtctatgac agcaaccttg 3775681 atttcgcagg ccaagccggc atttataaaa accaagataa aggttaccag tactttgact 3775741 gggacggcac gattaatggc ggaaccaaac ttccggccgg agagtattac ttgctcgcat 3775801 atgccgcgaa caaaggcaag tcaagccagg ttttgaccga agaacctttc actgttgaat 3775861 aagaaaaagc cctgccgatt cggcagggct ttttaaagat cagtcagcaa acgcctcctg 3775921 caataagcga tacgatcgga gcttatcttc aaaatgatgc gtgatggtca ccaccatgat 3775981 ttcctctgtt tcatacgcgt tactcaaagc taacagccgc tccttaacct gttctttcgt 3776041 accaacaatc attcgatttc gattatcagc aattcgtctc tgttcataag gagaatacgt 3776101 atttttccga acagcttcat acgaaggaac tccctctaaa ggaataccct gctctcccgc 3776161 caaaagtgta aaatcaagca cagccccaag ctcctctgcc ttctcctccg tgtcagcaca 3776221 aagaacaaaa acagcaactg ccgctcgagg cgtatctcct aacacagacg gtttgaatcg 3776281 cctcttatac tgtctgacag taccctctcc gccctctcca ttgataaaat gggcaaacat 3776341 atagccagcg ccagattcag ctgcgagcag cgcgctttct ccagatgagc cgagcagcca 3776401 cacatccgga gccgttgaaa tatgcggcgc agcggtcaga ttcggaaaac ggtgtttgtc 3776461 atccgccaaa tcatgcaaat acatggtcag ctccttaatt tgctgcggat actgatcagc 3776521 attgcgctta ccaccgtcat tcagcgccca tgatgcaatc ggcattcccc ccggtgctct 3776581 gccaagcccc aggtcaattc ttcctggtgt cagcccctcc agaacacgaa agttttcagc 3776641 tactttataa gcactgtaat gcggcagcat gactcctcct gatccaacac gaattcgctt 3776701 tgttttcgct gctatatgac tgattagcac ctcaggactg gaccctgcca gccgttttga 3776761 aaagtgatgc tcagaaaccc aaaatctctt atatccaagg tcctcagcag cttgggcaag 3776821 cgcaacggtt tgctgtaagg ccgtttctgc attgctgccc tctgatactg gagattgatc 3776881 taatatactt aatgaaacca tccctaccac ctcatcctca tcgtatcact gatcccctat 3776941 tttttctcca aagccgctca cactgcttat cagtgtcccc tatcattcgc catttatttg 3777001 tgaaagcatg tccctatttg tcggaatatg ttacacgtga aacataaaaa cccctccaga 3777061 cggagaggtt tgctttagtt tttattaaag cccttttctt tcacgtagtc atttaaatac 3777121 gtacgcggct tttgcttcat aaagttcagt atttgatcgg accacgtttc ttcccgcttc 3777181 ccgtttgttc tttctctata gtaatcagaa atggttttgt catacgtatt catagtatga 3777241 cggaaatcgt ctgtgttcac attatacgta ttttcatgat aaacggcctg ctttggcaat 3777301 ctcggttttt tgccggaaag gttcgcagga tggcctactg ccagtccgaa aagcgggagc 3777361 acatggtcag gcgtttgcag cacctctgtc accttgtcca attcattccg aatgccgccg 3777421 atatagcaaa tgccaagccc catggattca gcggcaatgc tcatattttg cgctgccagc 3777481 gccgcatcaa tcaagctaac cataaacatt tctgtattct cgagcagctc agaaatatgt 3777541 tcaccttttt cctcagccag ttgttgatgg cggtacaaat ccgcacaaaa tacaaaaaag 3777601 tgtccgttct tctcaacgta aggctgattc ccagcaagca cggacagctc acgttttttc 3777661 tcaggatcag aaaccccgat aatcgaatat gcctgcacat agctggatgt agacgcagcc 3777721 tgcgcacttt tcactaatgt atcaatttct tcagctgtca aaagctgatc agtaaaagac 3777781 cggattgacc gatgattcaa aatggtttcg attgtgttat tcatcacaaa aacctcctta 3777841 tcacttttta tcatatccga aaaaaagtga tctcaaaagt gaaatgctct gcacaaaaaa 3777901 agacagcctc tgtaaaggct gtctgcatat caagaattaa aaagataact tctgtatttc 3777961 gtcagctgca cacttgcatt atatacaatc ccaaatccga ttaacgtgga aagtgtcgag 3778021 cttcccccat agctgacaaa cagcagcgga atcccggtaa caggcataat gccaatgttc 3778081 attccgatat tctggaatgt gtggatcaca attaacgccg tatagccaac gcaaaagaaa 3778141 gaagcgaaac ggttaaacgg atgtattttg tctatcagaa caacaagcct gtagattaaa 3778201 aagaagaaca tgatgacaac aattgcacag cctataaagc caaatgactc acctattata 3778261 gaaaagataa agtcagtcgt actctctgga acataaacct tcaaattaga aataccatta 3778321 cctaaaatac caccagatcc tattgccatg atggcctggt caacttgcca gctgtcattt 3778381 gaatcttcct gtgtctcatt tgaagcagac acccaagaag tgacccgctt aatttgataa 3778441 tcctgtattc caactgattt agcaacgtca ggaaagttta tcattactaa taaaattaat 3778501 gaaatgagta agatacctga accagctatg atcgcaatca atttccaatt tatccctgac 3778561 ataaaaacca ttacaagaac gataaacata catattcccg cagtcccagc atcctgcatc 3778621 aggataagac ctacaggaat aactgcgaca cccgcaatct ttaataacaa gtggatatca 3778681 tccctaagcg tccgaactcc tttaggattt gcttttccaa taactgaagc aagcatcata 3778741 atcaaaccaa ccttcataaa ctctgacggc tgtattgtta ttctaccgat cctaaaccaa 3778801 ctttttgccc ctttaataac aggtgcaata gactcgggac tgattttaag aataatcaaa 3778861 gataaaatac caatgataaa aatatataaa cttaactttt caagctgttc taaatcaaag 3778921 tacaaaagaa ctgtaatggc tacagccccc aaaagataaa acacaatttg ctgaatccaa 3778981 tccgtgttcc catactgccc aaactgaccg gcagcatata ttgatactac gcttataata 3779041 aaaaacacac caaatataaa aatcaaatcc ccctggtaaa aggggctttg ctgtttctta 3779101 tatcgactca ttctatcccg ccttacattt tcatcggaaa atcactaatg tttattatac 3779161 atgaaccacg ttcaagatga cacgtgaagc tcgcttcctt ttatgttttt tcagcatttg 3779221 cggcgctttt tcagctacac gaaatatgac gtatcataaa ccgaaatgtt tcgattgaca 3779281 caaaactttt caaatgaaaa aaacgccata ccaatagaat ttgttaaaaa acgaatgcga 3779341 taatgtgtta tgttcccaaa taatgtgata cctcatatag aaatagctaa aaattcagag 3779401 ccccatgccc atacattctc ctagcacatt aaacgaaaaa ataagacgat agatccagtc 3779461 catttctgca aaaacacgta tcaatttctg gaaaacatgg tataataatt gtaacagaat 3779521 gttcaaaaaa caatcacaaa acagacacaa ctcagttcct ctatttcatt tttgtaaacg 3779581 ttatcacaaa atgaaaggag acgggtatga tggacatgtt ttttgcttac ttattggttg 3779641 ccagcgcaac gcctctcttt atttggcttg ataacaaaaa agtcgcactc tcagctattc 3779701 cgccaatcat tttaatgtgg gtattcttct tcttttacgc aacagaaagc ctttctccac 3779761 ttggacacac tctcatgatt atcttgtttg ccgttaacgt cattgtcgct catatcgccg 3779821 catttatcat ttacggcctt ccgtatcttc gcagaaagcg aagcagctga agacagcaaa 3779881 aaaccctctt ccactgaaga gggttttttg tattattcgt tatggcctga atgctctgag 3779941 tgttcagcgc ctccaggagg atttccgtcc atatggtcac catggtgata gtgagccgcg 3780001 aaaatccaga tggatccaag tacgataacg atcgcgccaa agaatccgaa cagcgtgttt 3780061 ccgacttgga tcgtgccgtt ttcgctctct gtcatatgca tgaacatgag aagctgcagc 3780121 gccgcctgaa tgaaggcgaa gccgaagata atccaaagtt ttgctgatga gctcaggtca 3780181 gtatacactg caacccatag agccagcagg gtcaaaacga tagacaggat aaaacctaca 3780241 atgtgtttcc atggaaagtg actgtgttca gcagatttgt ttgccatttt acagaccccc 3780301 caatcccatg agatagacac ctgtaaagat gaaaatccat acaacatcta agaagtgcca 3780361 gtacaagctt gagataaaga ttttagatga agtttgcgga gttaagccgc gtttcttcaa 3780421 ctgaatcaga attcctgtga tccagaaaat cccgattgtt acgtgagttc cgtgagttcc 3780481 aagtaaaaca aagaatccag accagaacgc acttgtactg agagccgctc cttcatgtac 3780541 atagtgaaca aactcgttga tctcgcatcc gacgaagccg gcaccgagaa gaagagtgat 3780601 aattgtccaa atgactacgc cttttaaact tccgcggcgc atttcatgaa cagcgatccc 3780661 gcaggtaaag ctgctgatca gcagcaagaa cgtcataatc attaccagat tgacttcaaa 3780721 tagttcgtct ggcaagacac ctccagctgt tctgttttta agaacgaaga aggttgcaaa 3780781 tagtgttgag aacaacacaa tttctgcccc taaaaagatc caaaacccga gaatattaag 3780841 tctgccggtt tcagattgat attccatagg cgcgttagaa ttgccgtgtt ctgcatgttc 3780901 cataactcac gcctccttat tcggaaatct ttctttccgt ctcttttatt tcatcaacac 3780961 taatgtagta gccgttgtcg tattcgaatg aacgcagaac catgcagagc aggactccga 3781021 tcaatccgac tacgcccatc cagtaccatt caaagacaag tccaaagcct gcgagaccga 3781081 aggcaacaga cataaagaac ggtctgcctg agttgcttgg catatggatt ttcttgaatt 3781141 tgctttcagg gtataattca gttttttctt ctttcatatg caggaatgca tcttgagatt 3781201 tgacttcagg aagcaccgca aagttgtaat gcggcggaat cgcagaagaa gtcgcccaat 3781261 caagcgtacg tcccacaccc catgaatctc cgctgatttc acgagtagag taacggaagc 3781321 tgtagtagat gttatagcaa aggattaaga atcctacacc catcatgaaa gctccgactg 3781381 ttgagataaa gttcaatgtt gtccagccgt cattcggtcc gtatgtgtaa atacggcgcg 3781441 gcatgccttg aagccccaag aaatattgcg ggaagaaaca aatattgaac ccgatcataa 3781501 agatccagaa gaaccatttt ccgattcttt cgttcagctt gtggccgaac atttttggat 3781561 accagaaaat aaatccggcg aaacaagcaa atacagtacc cgcaatcagc acatagtgga 3781621 agtgagatac aaggaagtac gtattatggt attgataatc cgctgctgcc atcgcaagca 3781681 taacccctgt aaccccgccg ataacgaagt taggaatgaa cgcaagcgcc cacagcatag 3781741 gtgttgtaaa gctgattcgg cctttataca ttgtaaagag ccagttaaag attttaaccc 3781801 cggttgggat tgagattgcc attgtcgtaa ttgagaagaa tgagttaacg gacgcactgt 3781861 tccccattgt gaagaagtgg tgagtccaaa ctaagaaact caatacagag atggcgataa 3781921 tagaaccaac catcgctttg taaccaaaca attgttttct tgcaaagctt gagatgattt 3781981 ctgagaaaat accaaacgcc ggaagaataa cgatatatac ttcaggatgt ccccaaatcc 3782041 agaacaagtt agcccaaagc atcggcatac cgcctgcttc caatgtgaaa aagtgagcgc 3782101 cgaacaaacg atcaaatgat aaaagtgcta atgctactgt aagtacaggg aacgcaaaca 3782161 cgataataac cattgtgatc agtgttgtcc atgtgaacat cggcatacgc attaatgtca 3782221 tgccttttgt tctcattttt aagattgtta ccataaagtt gatccctgtc atcagggtac 3782281 cgataccggc aatctgaagt ccgaggaggt agtagttctc acccggccca gggctcatgt 3782341 cgttacttgc aagcggcata taactcgtcc agcctgcgtt cggagaacct ccgataacga 3782401 aagaaatatt gaaaagcatc gcccctacaa agaacgtcca gaagctcagg ttgttcaagt 3782461 aagggaacgc aacgtcgcgg gcaccgattt gaagaggcac aacaacgttg ataagaccga 3782521 ttaagaacgg catcgccatg aagatgatca tgattgtacc gtgagttgta aaaatttcat 3782581 tatagtggtt tgagtctaaa aaactgttat tcggaagcgc tagctgggca cgcatcatca 3782641 gaccgtcgac accgccacgg aataacataa ttacagcaga tataatatac atgattccga 3782701 gttttttatg gtcaacagta gttatccatt cagaccacag ccatttccac tttttgaagt 3782761 aagtcagaac aaaaataatg gcaatggttg aaagcgcaat ggaaacttgt gcgcccagaa 3782821 ttaatgggtc accagttacg aaaaattcgt cccatttgaa tttcatgcag gcttcctcct 3782881 ttcctgatca atatcattct tctgtatcat cagacttctt aaattcgttt ttctttacgt 3782941 tttcaaacgg atctgtttta gaatgcggtg aaacggcttg atagccaagg cgtttgcgcg 3783001 cctccatcgc gtactcagcg tcttgtccgt gatcaacgta tttcaagtga gtagaagaga 3783061 acgttaattc gtccacattt tcaggaagca tcaattcatc atacttctct tttgtcagct 3783121 taggagcctc gttctgagtc tttttcaccc agctgttaaa gtctttttct gtgactgcat 3783181 tcacatcaaa ctcttggtct gcaaaatgtt cacctgtgaa gttcgcgttg cggccttcgt 3783241 aagtacccac tttgtcagcc tgtaagtatt gatccatcag cattcctgcc atcgcatatt 3783301 tttgccctcc aagctgagga atccatagcg aagccattga atctgcagat gagattttga 3783361 acaagatcgg gcggtcgaca ggaatgttta agtagttgac cgtttcaata tcctgttcag 3783421 ggtagctaaa tacccatttc cagtctaccg aagtagcata aacaacaaga ggctctttgt 3783481 cttttgttgc ttcaggagct ttttctaacg aatatatcgt ctgtactgtt ggcacagaaa 3783541 gtgcaatgac gattaaaatt gggatcactg tccagactac ttctaaaaac gtgttaccgt 3783601 gaatttctgg gttataagat ccattatctt tgcctttacg gtcgcggtat tttactaaaa 3783661 taatggtaaa tagaacaaag acgaccccga cgataaacag cataaatccg atagataaca 3783721 ggattaaatc actttgctgt tcagctacag gtcctttcgg atctagtact gaagcattgc 3783781 tgcatccccc aaggacgaaa accacagtta acagcgctaa tacaagcaac ggttttaatg 3783841 ctctgaacaa gaagatcacc atccttccta ttgatgtaat aaatctgaag tgcatacttc 3783901 ctcaaaatct tttctctact ttgttatgct atcaaaaact tcacttatta gctttatttt 3783961 tttataaact tcatcccatt ttcgcttaaa tgtcataaaa tcgacaaaaa ttgctccaac 3784021 tttattcaca tctatcgctt aagatgaaaa gtttctagtt atttccgcat ataaagtaaa 3784081 gaaagatgat gaagaactaa ttctgacaaa ttaaggttta ccacaataaa aaacttaggt 3784141 caatcaaaaa tttcattttg ttaaactttc tagataggaa ttattttttc ctcgtctagc 3784201 atcttttcac acggttacca ttttaacgca tcaaatattg aaagaaaagg cgcaatgaag 3784261 agccaatatg ctctgaattg tccgtatttt tttatgagag catccagttg tttatcttat 3784321 acaaaaaaga ggaatgatat aagcaaataa ataaaaaata ggatgtgttg catgatgagt 3784381 tttcttattt cacttatcgt cgctattatt atcggatggc ttggaagcct gtttgtaaaa 3784441 ggagatatgc ccggaggaat tatcgggtct atgatcgcag gtcttatagg cgcctggatc 3784501 ggacacgggc tgcttggaac atgggggccg cacctagccg gatttgccat tattccagcg 3784561 gtaatcggcg cagccattgt tgtctttcta gtaagcctgt taaccagaaa aagaggataa 3784621 aagcagcagc acccgaagcg tcagcgcttt gggtgtttgt tttgccataa aaatcgaaaa 3784681 agcctcaacc ctagcggttg aggcttttga ctggtttggc gcccaactga tcgatgaacc 3784741 ttctgaaggc ctgttttccc tctgctgtct gcttaaatac accggcgtgt tcaaggatgc 3784801 gcgcgaatac atgtcccagc tcttctttta tgactagatc tacgttctct tttgttatgg 3784861 ttcttttttc catcgtccga agagcccact cactatgctt tgcagtgagc ggattttgtt 3784921 ctaaggctgt tttcggatca gcagaacata gcgccgctgc cgtttctttc atttcctcct 3784981 gtaagcggcc aggcaatatc gccaatccca tgacctcaat caggccgata ttttcttttt 3785041 taatatggtg gacttcttga tgaggatgaa atattcctaa tggatgctcc tcatccgtcc 3785101 ggttgttcct cagtacgata tcgagttcgt acaagtctcc cctgcgccgc gcaatcggtg 3785161 tgaccgtatt atggggcgta tcgcctgtat aggcggcaat gccggctttt tcatcggaat 3785221 acgtctgcca cgtgcggaag atatggtcag cagcttcggc gacatgaccc ggttcgtctc 3785281 cttggagcct gagcacagac atcggccact tcactaagcc cagcgacacg ccgggataat 3785341 catttaattc ataaacgtct tccgcttctg cacgtgccat tggaaaatca tgcgcgccgc 3785401 cttggaaatg atcatggctt aggatgctgc cgccgacaat cggcagatcc gcgtttgaac 3785461 cgataaaata atgcggatat tggccaagaa atgacagcag cctttcaaat gtttttttgc 3785521 tgatctccat cggttcatgt tcacctttta agacaatgca gtgctccgga taatagacat 3785581 atggcgagaa ttgcaggaac cattgttcgt cctcaaggat gaccggaatg attctgtgat 3785641 tttgccgggc tggatgattc acgcttccct cgaagccgac attttcttta cacagcaaac 3785701 acatcggata atttgtctgt tcctgctctt ttgcagccgc aatcgctttc gggtcctttt 3785761 caggctttga taggttaatg gtcatttcca gctcgccata ttcggtcggc accgtccaat 3785821 gaacattttt ggcgattctg tcagtccgta tataatagac atcctctgaa tattgataga 3785881 attcctttgt cgcctgtttt gggccgtata atgcttttgt ctcttcaaat ttgcgaatga 3785941 cctcggacgg ggcaggcaca aaacagccca tcagctttgc gctgagcagg tcacggtacg 3786001 tatctgtatc cgcttccatt cggccggttt cggcagccca tttatagatg ggagctagca 3786061 agtccggcag gctttgtgac tgcttgatgc tggtgctgga gttcggctcg ggatgtgtga 3786121 tgcccagcgc ttcataaaga cggtttctcg tatattcccg atcccagatc gaaatcaatt 3786181 ttcgttccag gccatactca agcagctgtt ccagatgttc aataatactc atatgtcact 3786241 ccccctttag ttctctcgct ccctctccga tatccgcgac ataaaagtcc gctcggagcc 3786301 ctgttttttc ttgatatctg tctccaacct tctgaataaa atcatcaacg aactcatctt 3786361 ttacaatgct gatggtgcag ccgccaaagc ctgctcccgt cattcttgat ccaattacac 3786421 cttcgtgatc ccatgccgca aacacaagct catcaagttc agggcatgtt acttcatagt 3786481 catccttcaa tgaaaggtgg gattccttca ttaactgccc gatttcatct atattgttct 3786541 ctttgaacat atgggccgtc ttaatagcac gatgattttc gtatacagcg tgctttgccc 3786601 ggcgtctgtt cgtttcattt tggatcaggc tggaatgcgc atcgaaatca gaaggcttga 3786661 tgtcgcccag tgcggcaata tcgaggcctt ttttcagatc aagcaatgca tcattgcatt 3786721 cttggcgtct cgtattatag ctggagtcag ccaatgtcct ttttttgttc gtgttcgcga 3786781 tgaccagcgc gaggcctgag acattgagtt tgctatattc atagtcaagc gtgtcacagt 3786841 tcagcagcat cgcatgatgt tttttcccca ttccaattgc aaattggtcc ataattccgc 3786901 aattgacgcc gataaaatgg ttttccgcat gctgcgccat tttcacaagc tcaagcgcat 3786961 ctacttcagg atgaaaataa ctttggagca cgacccccat cagcagttca atagaagcgg 3787021 aagacgacag tcccgccccg tttggaatat tccctgaaaa tacaatgtca aagccatggg 3787081 gaactgcata tcccctctgt tgaaattcat aaatcacgcc ttttgggtag ttcgcccagt 3787141 cgtcttcttt ttgatagcga atgtcgtcaa ggctgcattc cttgatgcct gcgtttctaa 3787201 agttatctga atacatccgg acaagcccgt cgtttctttc tgcaacagca gcatatgtac 3787261 ccattgtcag cgcgcacgga aagacatgcc cgccgttata gtctgtatgt tctccaatca 3787321 gattcactct tccaggtgcg aaaaaaaacc gtaacccctc tttttctccg aatacacttg 3787381 caaatatccc ctttagctct tcccgcatgt gcaatcacct ttctggtttt tattttttat 3787441 tccccttatt tcttcataga aaacggcaga tcatatgctg cagtcctctc ataccccttc 3787501 ttcttttgtt tttttaaaga cgagccattt gctcgcaaca tagttgacga caacaatgac 3787561 cgcgttgtcg agtattttgg ccaaggtttc atttgtattg aactggccga caagaatgat 3787621 catcatgcct aaatctatgc cgagagacag gacccgaacg ctgaaaaaag cagtgagctc 3787681 tttcagcagg ctctgcagat catgtgtttt ttgctgaaac acatataatt tatttgttat 3787741 gtaagcaaac agcacggaca aaatccaagc ggcaacagtg gcggctttgt aatccacatt 3787801 catgatctct accaatatat aaaagctggc gatattcaca atggttgtga aaacccccat 3787861 aatgatatac ataattattt ctctatactt cactgatgtt cctcgctttc tgaaaaactt 3787921 ttcaaaattc ttggcctctc gtgctctctg tctaaagtaa aaaataccga gagtgcgtct 3787981 aaaaagctgc ggaaggtggc tggctggccc aatacatatg attgtttgat gattccgtcg 3788041 aggactgcac atattatttt agccgtatat tcaggatcaa tacaggcgtc aatcagcttt 3788101 ctctccttca gccacttaat atataacaca ttttcttcca cccacaattc gtacagccgg 3788161 acataggcct tgcatttctt taagacttta tatgtcggca tgttcatggc aaacgaggtg 3788221 atgtcccacg acggcttatt tatgtaatag gaataaagca gttctgcagc gtgttttgca 3788281 gcctcgtcca atgtcagcga tttcactgac tcccgctcca tttgatcaag ataccctata 3788341 atgatctttt ttttcatctg acgtttttcg agaaggtaca gcagaaaatc gtccttgctg 3788401 acaaaatgaa cataaaatgc tcctttgctg tacccggcgg ctctgctgat atcttctaca 3788461 gaaaccggat catacgctcg gtcaatcaac aaattcacgc cagcgtctat aaaactttca 3788521 aatgttgctt ctcttttaat ttgaaatttg ttttttttca tatttttctc ctggcggtaa 3788581 tgattaccct tatcttacac cggatcaatc tttagcggta tttatttctt taaacggtta 3788641 tgctattcgg tttcccaggg gtcattttta ataggctaaa tgatttattt tcatttacat 3788701 actatccagt cagtatttaa ttgtttatta ttataaataa ggtccattgg ttatattagt 3788761 cattttttta gggaataggt aggtggtttt tccttcagtt tgtgaacacc gagcaactat 3788821 gtgtgaaatt tgttgtactc gcctccatca tcgcgctggc ttgtctttta ttgcccgcat 3788881 gttgcaggaa aacattttat acaattggag gttactatga aaactcatgt taaaaaagat 3788941 ttggacaaag gttggcatat gttaattcaa gaagctagat ccattggatt aggcattcat 3789001 gatgtgaggc agtttttaga atctgagaca gcatcaagaa agaaaaacca caaaaaaacc 3789061 gtccggcaag actagtccga acaggcggat ctatttacct ctggcttttc tatcacctga 3789121 tctgagtttt caccatatcc tctattcaaa agcaaatcgc tgcgctgagc ttgaggacaa 3789181 acggtgtgtc agctaactac gacagacagc cggtgatgcg atcacctctt ggcacatgca 3789241 ttgtcataaa gaggtgatgc gaacatgata accgtgctct ggtaaacagc agctttgctg 3789301 agaacaagct gcattcggtg aggttttgaa agcaaactcg tttatacacg gccgagcttg 3789361 aaaaccttcg cctgtcttta gaccactgtg ttcacctctt cacgacttcc ttcttttttc 3789421 atcctccagc tattgtacaa cgcataaatc ggactttcag tacataccta ttggtgtacc 3789481 tttttgctta cgtttagcga ataaaaggag gaaagccatg tacaaagctg attataaaca 3789541 gattgctgca acgccgtctt ttcaagcttt tttaaagcag aaacgcgctt ttattgttcc 3789601 ttctgcgatt ttcttttttg ttttttattt ttcactccct gttttgacat cttatttcac 3789661 ctttttgaat gcaccggcca ttggagctgt ttcatgggct tggctgttcg ccatcgccca 3789721 attcgctatg acctggatac tgagtactgt gtattcccgg agagccgccc atttcgataa 3789781 gtatgtaagc gctttaaaag aggatctgaa gggtgaacag acatgaatat gactgctttt 3789841 ttattatttt tggcgattgt tggcctgacg cttattatca cgtattttgc cgcgaagcgg 3789901 acgaaaacga cgagtgagtt ttatacggcg ggcggcgggc tcaccggcgt tcagaatgga 3789961 ctggcaattg ccggtgacta catgtctgcc gcctcgtttc tcgggattgc cggaatgatt 3790021 gcgttatatg gatttgatgg cttcttttac agcatcggtt ttctggtggc ttatctcgtt 3790081 gtcttgtaca tcgtggcgga gccgcttcgg aatcttggaa agtacacgat ggcagacatg 3790141 attgccgctc gctttaaaga aaagaaaatc cgcggtgtcg cggctctcaa taccattgcc 3790201 atctctactt tttatatgat cgcccagctc gtgggggcgg gcgcgctgat caaactgctt 3790261 ctagggctgg attataccgc ggctgtcctc atcgtcggag tgctgatgac catttatgtc 3790321 gtgtttggcg gcatgatcgc gacaagctgg gttcaaatta ttaaagctgt tttgctgatg 3790381 gccggcacac tcgtgatttc gattatcgtg ttttcgaaat tcggctttag ccttaatacc 3790441 atgtttgaac agatgaaaac ggctactccg cttggcgctg attttttgaa ccccggaaat 3790501 aaatacaagg tgccgcttga gaccttgtcg ttaaacttgg cactcgtgct gggaaccgcc 3790561 gggcttccgc atatattgat ccggttttat accgttaagg atgccaagac ggcccgtaca 3790621 tccgttgtgt cagcgacatg gattatcggt gtgttttaca ttatgacggt atttctcggc 3790681 tttggtgccg cggcatttgt cggttttgac gcgattacgg cggctgatca agcgggaaat 3790741 atggcggctc cgcttttagc aaaagcgctc ggaggagact ttctgttcgc gtttgtatca 3790801 gccatcgcct ttgccaccat tttggctgtc gtgacagggt tggtgctgtc tgccgcctca 3790861 gcatttgccc atgatattta cagccagatc atcagaaagg gagaagcaac tgaaaaagaa 3790921 caaatgaaag cggccagatg ggcttctgtc gccgtgtcag tgctctcgat tctccttgcg 3790981 atttttgcac aatccttaaa tgtggcgttc cttgttgcac tcgcgtttgc ggtagccgcc 3791041 agcgcaaacc ttccgctgat tgtgtttaca gtcttctgga aacgattcaa tgcctcaggc 3791101 gctttatggg gcagcctgac aggcctgatc agcgcgcttg tgctggtatc gatgagccct 3791161 agtgtgtggg acccggccgg aggtgctatt tttaccggtg atccgctcat tccgctatct 3791221 aatccaggaa ttatttccat cccgctcggc tttctcggcg cgtggctcgg aacggtgctg 3791281 tcgtctgata aaacaattga tgaagatacg tttgcagaaa ttcaggtgaa ggcgcatact 3791341 ggcgtccata tggaacagga ataaaaaaag ctctctttat cgagagcttt ttccttactt 3791401 tttcttctgc tcgtcagaaa tcgctttttc aaatacatcc ttgccggcag cacccggaat 3791461 tacagtgtca ccgataataa aggttggaac ggctgtgatg tcagcctctt cataggcgtg 3791521 cttcaaggct tggcgctgca cgtcctgata tgttcttgtt tccagtgctg atttgaatga 3791581 tgcaccgtct aatcccactt cctcggcgag cttcgtcaag atgtcaatat cgccgatatt 3791641 ttggtcctcc tggaaaaatg cctgaaagac acgggtgttg tattcatgtc ctttattgta 3791701 ttccttcgca aaatggaagc cttcaaacgc gaggtctgta tacggatggg gcgagacgtt 3791761 tggaaaattg atctcgactc ctaatttctc cgccattggc tgaattgatg tctgccacat 3791821 gtactgttta gaaggatcat tgaccggatc aagctgagga gatgggcttg ggcgcagttc 3791881 aaacggcatc cactcgactt caacatcctt tccttttatc gcttcttcaa aagcggcttt 3791941 tccaacaaaa caaaatgggc agacgtaatc tgaataaact ttaatgtgta ctgtcatgat 3792001 aatctccttt catactaaat tgattttaaa ctgtaacaat taaagttaca actgtttttt 3792061 aataaagaag ccgatttagg cttctttcag attgatgaca aaatcctaaa aagttttagg 3792121 attttgtcat cctttcagcg tgattgaaaa cccttgaagt ctaggaaagc cgagcattgg 3792181 agcggagcga atgctctaat tcgtgagcac caacgcacag gcttgacaac gaatgcgagg 3792241 gtttgtcgac acgctgaaag aagcctgtaa aggcttcttt tatgattcca gcaaacgctg 3792301 ggcaatatat tctccttttt tgcagccgcc tgggcatgcg tataaagcag aaccgattgt 3792361 ttgtgtatat tcgtttaacg catcctttgc tgaaagagcc ttcagcatcg ggataaactg 3792421 attgtcggga tttttttgaa aactgataaa caggagacct gcatccatat agccggtttt 3792481 cggatcaagt ccttctgtgt aagagaaagc tcttcgcaaa atttgtttcc cagtagattt 3792541 cgctagactg acgtgtgaat tagacggaat ttgattcagc ttcacgggat ctgtttcctt 3792601 tttctgccca aaaggcgccc ccgagctttt tctgcggccg aaggtatcct cttggtcctt 3792661 gagggaagag cggtcccata cctcaaggaa cattttgatt ttccgaaaag ccatataggt 3792721 gccgcccgtc atccagtcag gctcaccaga ctgaatccac acgatcgagt tcatcaacgt 3792781 gtcatccttc gtgctctggt tgcctgttcc atctttaaac ccgaagaggt tgcgcggtgt 3792841 ttcaccattt tttccaccgc ttaaaaagcc tttgttcaca aaacggacct cacaagtgcc 3792901 gaccgcttga tttagcaggt tacgcagcgc gtgaaacgcc acttgctcgt cgtctgcaca 3792961 cacttgaatg cagatgtccc cgcctccctg cttttcatcc aggttgtcat tgggcatcgc 3793021 tggaagagcg gctaggtgct tcggtttttt gcttttcagt ccgaagcggt cctttccgtc 3793081 tttttcaaaa aagccaggcc cgaatccgaa tgtgaccgtt aagttggaag gggataaatc 3793141 agcagactca cctgtatcct gcggcggcag atactgattt ctctgctccg ctgacatttt 3793201 cttgccagac gtcagcatct gtgtgagact tgtccagttt ctaaataacg taatgatgtc 3793261 gcttttgtct tttgctgtta catccagtgc agcaaaatag acatacgtct gatgggcagt 3793321 tgtgattccg gcctgatgct ttccgtaaaa cggaacaatc tgctcctcct ctttttcatc 3793381 ctttttcgat ggcttagccg cagtctgaac aagcggagcg agaccgccga gaccgctggc 3793441 accgatcgca acggctgccc ccgccatcgc tccccatttt aaaatgtccc gtctgtgaat 3793501 ttgttctggc tttttctgtt catcgctcat gatgttacaa aactcctttt atagcacatt 3793561 cgcaatcttc gacatggttt cagaaagagt cgtcagctta gtgctcagct ctctgatttg 3793621 cttttcactt aatttatcat aagacgtata ggactgatca tttgttttgt attttgccat 3793681 taaaacttca aattcgctga actccgtatc cagtttttcc gtcaagtcgg agtgatcttt 3793741 tacaagcgcg cttttcactg tttgataaac ggcttcggag ccttccacat ttgccataag 3793801 gtcaactaaa tcaattcgtg agtagcgctc ttcttctccc gtgattttcg aaattccggc 3793861 ttcgttcaga agctccatcg cgcctgcaac aatttgttca ggtgttaatt tcagtgattg 3793921 aattgaaccg tcaagctctt ttacatcctt gagaagctgg tcagctgttg ccttttcccc 3793981 ggaaatatct tgatccttcc aaatggcctt ctcaagctta tggaagcctg tccatttgtc 3794041 tccttcttca acatcgtttt ctcgtgcgtc aattttcgga tcaagatctc cgaggctttc 3794101 agcgatcggt tcgattcgct cgtaataaac acgcgctttc gcatataacg ttttggactt 3794161 ttcgatatcg ccggatttca cagcacccgt aaatgcttca gtcgctttga caagctggtc 3794221 actctgctct ttgacatagc ctttatactc atccgctgct tttgccagct gatcgctagc 3794281 ctttttgccg ctcttcttcg cttctgtcag gtcttctaag gatgctttca atgactcgga 3794341 ttctgtcttg atttttcctg catccggttt gtctttttgc gcttctgtgt agattggctg 3794401 aagatgcttt tcgatttctg tatattcgaa tggatagtcg ctgcgaatat cgttttcaaa 3794461 ggaaagccag tagctgttta actctttccc cttcttttca atctcttttt ggtctccttt 3794521 ttccactgag tcattcagct tagaaatgat ggtttccatt ttatttacgg atgcggtgat 3794581 ttctttagtg accccgcttt tttcagatga agctttttct ttggttgaag atgtgtcatt 3794641 ggctccgcag cctgcgcaca gcgcaaggat gcatccggct gatacagcga tttttgtgaa 3794701 attcattttg tcagttcctt tccgtttgta aaatgttttg ccgcttctga aacaagcgca 3794761 atcagtaaaa agagtaaaat caacatttgc ggaatcgtgc tgtacacaga cggataaatt 3794821 cctagcaccg atacagacgg cagccagctt tctgcatcag acggaagaat gcccgccagt 3794881 tgaaggctgt gaacgccggt tccgagaaat ttcacgcaca tatacaggac aaccgccatt 3794941 gatagaagaa aaaacggctt caatggaatg cgcattccga gcttgatcat cagaacaccg 3795001 acgatgacga gaacgataag ccctgcggca gttccgccga tcagttcagt gagcgggagc 3795061 ttcccgacaa gcccgatgaa aaagatgacc gtttcgagac cttctcttac aactgccaga 3795121 aatgcaatga gcgcaaagga aagcaggctt cgttttttta gtgcctgtga cttctggata 3795181 ttgatttttt ctctccattt atccattgag gcgtttctgt gcagccacac cccgacatac 3795241 aaaagcatga cagcggacag tacgccggta acgccgccaa gcaagaaatt gttttctccg 3795301 aatacactgg aggagaacag aaccgtgaca ccgatgccgg ctgctaagga aacagccatg 3795361 ccggcggacg ccccgcccca gatccatgtc gaggaacgcg taacccgcgc tttttttgtc 3795421 atggttaata gcgctccgat gacaaggagg gcctccattc cttcacgaac cgggatcagc 3795481 gccgcatccc accagctgta gctgcttgaa gcgatcggct cgagcaattg aatcatttcg 3795541 tcaatttgct ttgatacctt ttcaggatgg ctgccgatct ccgccttcat cagcgccaga 3795601 ttttcctccg atgtcgtata ggcttctttc gattgggaca cgacatctcc ctcaacagcg 3795661 agccaggatg taactaaatt gtcgattgcg gatgacgctt catccaattg ttttttttct 3795721 atgaactgtt ttgtgtcttt caagctttgt atataggctg ttaaggacgc ccttgattga 3795781 cctgaggatg tctttttcag cacgacagcc tgctgatagg tttctaaatg agacgcaagc 3795841 tcttcaagct gtgttttgag cttacgtgcg tcttgattga taaaagaaag agaaatcatc 3795901 gcgatattcg cgtccatttc actgtgagaa gaaaggtttt ctttcttaat agaaggttct 3795961 tcttttttcc acttcgcctt gaaggtgtca aacgtttgtt gtgccgaatc catatccccg 3796021 tcttttacgg atttgatcat ttgcttgttt aattgaatta atgcggcgat cggatcatct 3796081 tccgcatgtg ccgcagaacc gaaaaccatc aacaagctga atagaataag tgccagcccc 3796141 cgagccatca tgttcctcct ataattgaaa atgattatca ttgtataaca taatcatagc 3796201 cagttcctgt cctttgtcaa ttaaaatttg aaggtctgaa aaccttgatg gacagcaaaa 3796261 aagctgtcct tttacagaac agccctttga aggaaaatga acgattatct tcctgtttta 3796321 tacgtttgaa tttcctcacg aaacttgcgt gcagcactct caggatcctc cgcctgactg 3796381 atggcgctga tcatactgac gccatcggcc cccgcttgga taacaggtgc ggcattatct 3796441 attgtgattc cgccgatgcc gacaattgga atgctgatgc cttggcggcg cactgcttcg 3796501 ataagagata caccctgtac cgctctcgta tcttttttcg tttcagtcgg atagatcggc 3796561 ccaagcccga cataatccgc tccgtcttct tcggcttgct tcacctcaga catcgtatgg 3796621 gcagaaacgc cgagaatcat atcacctatg gcagctctta cctctttcgc atttgcgtct 3796681 tcctggccga tgtggatacc atcagctttc agattcagag ccaattccac atcatcattg 3796741 acaatgaacg gaacaccagc ttcacggcaa gctgcctgcg ctttttcagc aaatttaatc 3796801 cgagcctctc ctgtcagcgc atccccgcct ttttcacgga actggtacag ggtggcaccg 3796861 ccttttaacg ctttttgtac aactgtaaca ggatcggctt tcgtattgtt tgaccccata 3796921 atgaagtata cagataataa ctctttcatc atttcccgag aaatacgagt catgagacag 3796981 tcaccctttc tatagtcgcc cattcttgga cgtcttgttc agtaacagtt gaaagcttgt 3797041 tcagcaattc aatctgaaag cttccagggc ctttgtcagc cgtctgctgt gcggcaagct 3797101 gagcggcgac cccatacgaa gaaatggccg caatagcagc aaacaatgga ttttcttcca 3797161 cagcgcaaaa cgcaccgacg acggaagtca gcaggcaacc ggcgcctgtc acttttgtca 3797221 gcagcttgtg gccgttatga agggtgtata catgtgacgt gtcggctatg acatcaactt 3797281 caccagttat cgcaatgacc gtgtttagct tttgtgccgc ctgctgagcc agccggatga 3797341 tgtcgcctcc accttcaccc gcatcaacac ctttgatcag ccaatcggtc acgccgacgg 3797401 tatgggcaat ttccgccgca tttcctctga ttgcagcaag gcgcacctca cgaatgatgt 3797461 cacgtgccga ttcagtgcgg aacggtgttg ctccggcacc gacaggatca agaatgacgg 3797521 gaacgccatg ttcattagct gattttcccg cgatgatcat cgcttcgact gactccttgc 3797581 tcagtgttcc gatatttaaa acgagtgcac ccgcaatttt cgccatatcg gcgacctctt 3797641 cttttgcgta cgccataacg ggcgatgcgc cgagcgcgag caggccgttt gctgtgaaat 3797701 tcgttacgac attgttggtt atgctatgca ccagtgggct atgccggcgg acagccgtaa 3797761 gacattttgc tgctgattgt gcatccatat ttgcatcatc ctttactatc ttttttcggg 3797821 tcccataaat acgatttcgt atgttcgagc caagctctgg cggcaaacga caagtacctg 3797881 tcctttctcc aaataatggc gaggtgccaa gggatgaccg gatcgacaag cggaatgact 3797941 ttcacttttt ccgggtcaag gccgcggcag atccgttccg gcaaaagccc gatcccaagg 3798001 ttggcggata ccatctcact aataaaatcc cattgtgatg tttcataaat gatatggggc 3798061 cggaacccag ccttgataca ttccgtcata attcggttgt gcaggacaaa atcctctctg 3798121 aagaaaataa aaggctcgtc cttcaactca cgcagctgac attctttctc atcagccagc 3798181 cggtgggaag ggtgaacgac aagcattaag gtttctttta cgattgtaaa cgaatgaaag 3798241 atatcttcgt ttgcgggaag gaccacaacg ccgatatcaa gagagccgtc cccgacacct 3798301 tcttggactt ttatagaacc gtcttcgact agctgaaagg tgacattcgg atagttttca 3798361 cggaaatcgc cgagcactct ggggaaaaac cccgatccga tcatcggcgg cagtccaatc 3798421 cgtacgtgcc ctttcttgac ttccataata tcatttaatt ctgacgtcag gttttgaaat 3798481 gatttaatga tttcctgcgc ctgcacatac atgctatgac cggcatcagt cagttccacc 3798541 tgcctgccgt ttcggtaaaa cagttcaatt ccgagctctt cttctaaatt tttgatcatt 3798601 tttgatatcg tcggctgaga aacataaagg gattgggaag ccttcgtaaa actttttaaa 3798661 cgggcgactt ccaagaaata tgttaaatgg cggatatcca tgcgcttcac cctttctata 3798721 gacaaaagga atacttctta ttcttaatat atattttacc tatagagaga ccttatgtac 3798781 aataagtata taagggaggc atcaatatga aaaaactgtt gctaaccgtt attcaaatcg 3798841 ctctgttatt tatatttgct cggctgatta attgggtgac agcccttctt catataaata 3798901 ttcccggcag tataataggg attgtgattc ttttcacatt attgcacttt aacattatca 3798961 agcttgaatg gatcgagctt ggtgcagcgt ggcttctcgg ggagctgctt ttatttttta 3799021 tcccgtctgc cgtcggagtg attgaatacg gagacattat gtcgaaattt ggtgtcagca 3799081 ttctgcttgt tgtcatcatc agcacgtttg tcgtgatggt gtctacagga acgcttacac 3799141 aactcatcgc aaagagaaag gagaaaaagc atacgtgttc atcggaattg taagtttgtt 3799201 tttaacggtt ttggtgtatt taggagcaaa aaaggtatat caacgctttc cgcgtgttta 3799261 tacgtcgccg ctattggtga cgcccgctgt attagtcggt ctgctgctgc tggtgaatgt 3799321 cccgtacgag tcctataatc tcggcggcgg attgctgacc gatatgctac agccggccac 3799381 cgtggcattc gcgatcccgt tatataaata tttccctgtt ttaaagaaat acgcagtgga 3799441 aattattttg aatgtggccg tcggttcatg catcgcgatt atttctaccg ctcttattgc 3799501 gaaatggctt cacctcggca ccggcttaat tgacagcctc gtcccaagat cagtgacaac 3799561 gccgatcgcg atgaacgtat ctgaaatgat cggcggtatg cctgccgtca cagccgtgtt 3799621 tgtgatttta accgctttgc tcggcacagt gatcggcccg atggtcatcc gttatttccg 3799681 cattgataac gaaattgcgc ggggcgtgct gcttggcaca agcgcgcacg gagcgggaac 3799741 gtcaaaggca tttgagctca gctctgtgtc cggcacgatt tccagcgtgt cgatgatctt 3799801 agctgcgatt atgacgcttt gcgcggcgcc gtttttgctt tcatttatgt aaaaaactgt 3799861 cctctcgagg gcagtttttt ttatgtgctt ccccttattg aaaagctggc gaattccaat 3799921 ataatgtatt tgtggatacc aaaggaggca ccctgatgca caacttgcag gtgaggcggc 3799981 attatgccgc gttaaaagga ttttatttgt ttgcttttct cggtacgggc agcataattc 3800041 ccttactcag tatgtattta acgaaggaac agcatttaag cggatcacag gtcggcttga 3800101 tcatgtcact gggcccgatt gtgatgattt tctttcagcc gttttggggc atgctgagcg 3800161 actatacgca aaaaacgaaa ggcctgctgg cggtttgcac atcaatcaca ggcatcattg 3800221 gattagccta tattgcattt gacagtttcc ctctgtttat tttgattgcg gcctgttttg 3800281 cagcctttca aagcacgatt attccacttt cggacagcat ttcactaagg tacacacaag 3800341 aaacaaacgg caactacggc ggaatccgcc tgtttggttc tctcggcttc ggtgtcgcgg 3800401 tgtttgccat gggacaggtg acgaaccagc tgtaccccat tcacgtgatc tttatctttg 3800461 gctgtgcctt tctgtgcatt gctgccatat tggcttcaca agtgcccggc cagcagaaaa 3800521 caacaaaggt caatatccgc aaaggattcc gggagcttat cagcaacaaa actttcctca 3800581 tctttatgat catcaccttt acgacatttg ctccaaactt agcgaacaat acgtatttca 3800641 gtctttttct ggacaaaagc ggcgcgtcac tttccgctat cggcatttta tttttcatcg 3800701 gtgtcatttc agaaattcca tttatgagat tcgcccaaac atttatagat aaaatggggc 3800761 tgctcaacgt cattatgctg tcaggcggag tctcattatt caggtgggcg ctctatttca 3800821 cggcgccttc actatggatc atttatgcga cggtctttct tcagggagtg gccatcggtt 3800881 tatttatccc ggcggcgctt caatatgtga aaaagattac cccaagacac gttgaagcga 3800941 cggcgctgac catgtacgcc gccattggca acgggttcgg caactggttc tgcacatttg 3801001 caggcgggta catttttgac tacgtgtcga tcttcgcagt ctacttgctt tttggcattc 3801061 tgagcatagc aggctttggc ctgacattat atttaatgaa ggctgaaaaa aacaaacata 3801121 cacttcatca gccggctgtt acttttaaac cataatgact ataatgaaca aaagaaagga 3801181 tgtgcgttat gaacgggcaa gagcgaaaca gcatttcgaa agggttgcag gttgatattg 3801241 tattgaaagc agatcaaaaa acaggaaaac tgacgagagg gacagtgaag gatattttga 3801301 cgaaatcaaa ctttcatccg catggcatta aagtccgtct tgaagatggc cgcatcggcc 3801361 gcgaccagca gatcgtttct acataaaaaa aagctgcccc tgaacagggc agctttttca 3801421 tttatttttt ctgcagaagg accactttca ggtagttgcc ttccggaaat gccgaaatcg 3801481 ttttgaaatc ctccggcagc gtaaattcct caatgatcgt gtagcgttca tttgtttctt 3801541 taaaggcggc atcaataaag cctttgaact tcttcatgcc aaaggcgctg ctgtttgtag 3801601 aggcaacaat gacacccttg tcagcagtga tggcgatcgt ttccttcagc aggtttttat 3801661 aatccttggc cgcgctgaag gtgcgttttt ttgtgcgcgc aaaggaaggc ggatctagaa 3801721 taatcagatc aaagcgcaaa tccttttttg cagcatatga aaaatagtta aaaacgtcca 3801781 tcactttaat gtcgtgcgct tcgtaatcca gcttgttcac gctgaattgc tcgatcgttt 3801841 tggcaagact tcgatttgcc acgtcgacgc ttgttgtttt ctccgctccg ccaagcgccg 3801901 ccgccacgga gaatgcaccc gtataagaaa acgtatttaa aacggttttc ccttttgcat 3801961 agcggtctct gatcgccttg cgcacatgtc tctgatccaa aaagatgccc gtcatggcgc 3802021 cttcattcag atccaccgcg tattgaatgc cattctcttg gatgatgatc gggaactcgc 3802081 cccttctccc tttcacgaag tcatcatctt caacgtattg tccagccgtg tcgaagcgtt 3802141 tcttctcgta aatcgcttta taatcaagat ccatctcatc caatgcggaa atcagcatgt 3802201 ctttaaaggt gtaaattccc ttgctgtacc attgaatcag caggtagccg tcataatagt 3802261 cgatggtgac gccgccgaca ccgtcaccct caccgttgaa caggcggaaa gctgttgtat 3802321 cttgagcctc aaatagtttg gcgcgcgctt gggccgcttt tgttaatttg ctgagaaaaa 3802381 atgcttggtc aatctgttca tgtttattgc gggtaagcgt ccagccaacc cctttgtttt 3802441 gcaggccgta atagccccgc gcgagaaact cgccgccgct ctcagacacg atatcaacga 3802501 ggtctccttc tttcatgtgc cccgcactcc ctgcgagagc ttctttttca ataaggggat 3802561 agcctttttt tattttggca gcgtgtgctt tttttagggt gagtagcttc atatatgtcg 3802621 tcctctttcc gtttgctttc tcttatggta ccacaaaacg ccaagatgtc tgcattgaca 3802681 gaaaggaaag gtttttctac gatagacaaa aagagttacg aggaggagca gcatggcaaa 3802741 acgaattgac catacaggca tcatggtaag agatattaac gcgtccatca cattttatga 3802801 agaggtacta ggcatgaaat tgaaggatcg catcactcac acgaacggtg taatcgagct 3802861 tgcttttctt ggctttgaag acggcccgga aacagaaatt gaactgattc aaggctacag 3802921 cagcgagctt cccgctgaag gaaaagtgca ccacattgcc ctgctgacgg atgacatcgc 3802981 ggctgaatat acaaaagcgg aaaaaatgaa cgcaaaattt atcgacgagg agatcacaac 3803041 acttccaaac ggataccgtt atttctatat cgaaggccct gacggtgagt ggattgagtt 3803101 ctttcagcgg taaaaataaa gaacgtacat tttgtgatgt acgttctttt ttatctatac 3803161 caactgatat acgttgactc atcgcaaatc atagcttccc agcccatacg ctcaaccaat 3803221 tcatggatgt ttttatcttt ggctaaaaag acattaatga atgagtcata tacactcata 3803281 aacacaaaat ccattttctc atcagttaaa acgagctctg ttgcggcttc atcaagaacc 3803341 gtccgcaagt tggcttcagt tatgtccaaa acgccgcggt tttccacaat cggttctgcg 3803401 taataaaacc gattggatcc gttcgcacct aataccttta ccaaactcgg aatatgaaaa 3803461 tttgaaatat gatcctcact gggataatag aggtctccat ttatgttttc atgtaacacc 3803521 tcagccaaat cctctctcgc gaactcgtcc cttaaagcgc ctatcgacgt cattaaagcc 3803581 agcgccagct cagcatgtgt ttgaaagccg caagaagaca taaccttctt ccaggaaaca 3803641 gccttgccta ttcctcttat ttcattatcg tttggataaa tatgttcata atcatttttt 3803701 ctttttgcat tctcccatcc ttcaggcatt tggataaaag gagaaaagat aagagcagca 3803761 gatgagtatt caactggtac ttgttgtaag attggtgatt cgtcatctaa ccatatataa 3803821 tctagcatgc gcacctcctt tacatattct aacattcctt tcgtttgaaa gagatgatca 3803881 gccctatgac aggctgatca tctatcacat cacattttta tccccagatt caaccgcact 3803941 ctcttcccgc catttttgat gatcccatat tctgaaaaac ggatagtaga tagcacaggt 3804001 gatcagcaga tttaccagct gcataactgc gcccgacacc tttccgcctg tcgccaggta 3804061 acctgatatg agcggcggca tcgtccatgg caccgcgatt ccggccggtc ttgccaccag 3804121 cccggtgctc atgccgatat aagtcgcggt aatcgtgagg agcggtgcga tgataaatgg 3804181 gacaataagg aggggattca tgacaatcgg catgccgaaa atgatcggct cgttgatatt 3804241 aaatagcgca gggccgattc ctaatcgtcc aagctgcttc atttgtttgc tgcgggagcg 3804301 cacaagcatc gtcaggacaa gcgccagcgt cgccccgctt ccgccgacat tgatccaaat 3804361 ttgaaaaaac tgagtcgtaa aaatactcgg cagcgcctcg cctgcttgga aggcgagacg 3804421 gttggcatcc atcgcgccgt accaaatcgg cgccatgatt ccgccaatga tggaagcccc 3804481 gtgaatcccg cacgaccaaa gcagcatctg cacaaattca gcgatcaggc ttccgccgag 3804541 actgccgcca aggatggaaa gcggtgtgcc aagcaggtct cctacgacat tgtgcagact 3804601 ctgaaaaggt gtcatttcaa tcagaagacg cgccagccat acgagaagca caatgataaa 3804661 gccgggaatc agcgcgacaa atgatttgct taccgcaggc ggcacaccgt ctggcatttt 3804721 gaagacgata tttttttgaa taatgtaccg atagatttcg gttgaaaaca aggcgatcag 3804781 catggcgaca aataagccct tgctgccgag cagcgtgatc gggattccgc cccctaccat 3804841 gatggactcc gttgagccat gcggtgtaaa cggcacctca aacggtgttg ccagcagaaa 3804901 tgcggcaatt gaaatcgctc cggcagaaag ggcatcgaca ccatagcttt ctgccagccg 3804961 ataggcgatc ccaaaagcgg caatcatcgc cataatatca aacgaagcgt taacaggata 3805021 tccgagctta tcggcccact cgttcccaaa cacactcgcc atgaaatcag cataccccgg 3805081 aatcggcaag ctcgttaaaa tcaagaagac agacccgata ataatcagcg gcatggtcag 3805141 gataattccg tcacgcaaag cgctgagatg ccgctgcccg gcaattttcc cggcgacagg 3805201 cattattttt tcctccatca cccgagtgaa tgtgctcatc ttaaaaaccc ccttttctca 3805261 ttgctttgtg aacaacctcc gcaatgtttt ctttatctta ttttgaaaac gcttacaaat 3805321 tcatttggaa aatttcctct tcatgcggaa aaaatctgca ttttgctaaa caaccctgcc 3805381 catgaaaaat tttttccttc ttactattaa tctctctttt tttctccgat atatatatca 3805441 aacatcatag aaaaaggaga tgaatcatga aaaacatgtc ttgcaaactt gttgtatcag 3805501 tcactctgtt tttcagtttt ctcaccatag gccctctcgc tcatgcgcaa aacagcagcg 3805561 agaaagaggt tattgtggtt tataaaaaca aggccggaaa ggaaaccatc ctggacagtg 3805621 atgctgatgt tgaacagcag tataagcatc ttcccgcggt agcggtcaca gcagaccagg 3805681 agacagtaaa agaattaaag caggatcctg atattttgta tgtagaaaac aacgtatcat 3805741 ttaccgcagc agacagcacg gatttcaaag tgctgtcaga cggcactgac acctctgaca 3805801 actttgagca atggaacctt gagcccattc aggtgaaaca ggcttggaag gcaggactga 3805861 caggaaaaaa tatcaaaatt gccgtcattg acagcgggat ctccccccac gatgacctgt 3805921 cgattgccgg cgggtattca gctgtcagtt atacctcttc ttacaaagat gataacggcc 3805981 acggaacaca tgtcgcaggg attatcggag ccaagcataa cggctacgga attgacggca 3806041 tcgcaccgga agcacaaata tacgcggtta aagcgcttga tcagaacggc tcgggggatc 3806101 ttcaaagtct tctccaagga attgactggt cgatcgcaaa caggatggac atcgtcaata 3806161 tgagccttgg cacgacgtca gacagcaaaa tccttcatga cgccgtgaac aaagcatatg 3806221 aacaaggtgt tctgcttgtt gccgcaagcg gtaacgacgg aaacggcaag ccagtgaatt 3806281 atccggcggc atacagcagt gtcgttgcgg tttcagcaac aaacgaaaag aatcagcttg 3806341 cctccttttc aacaactgga gatgaagttg aattttcagc accggggaca aacatcacaa 3806401 gcacttactt aaaccagtat tatgcaacgg gaagcggaac atcccaagcg acaccgcacg 3806461 ccgctgccat gtttgccttg ttaaaacagc gtgatcctgc cgagacaaac gtccagcttc 3806521 gcgaggaaat gcggaaaaac atcgttgatc ttggtaccgc aggccgcgat cagcaatttg 3806581 gctacggctt aatccagtat aaagcacagg caacagattc agcgtacgcg gcagcagagc 3806641 aagcggtgaa aaaagcggaa caaacaaaag cacaaatcga tatcaacaaa gcgcgagaac 3806701 tcatcagcca gctgccgaac tccgacgcca aaactgccct gcacaaaaga ctggataaag 3806761 tacagtcata cagaaatgta aaagatgcga aagacaaagt cgcaaaggca gaaaaatata 3806821 aaacacagca aaccgttgac acagcacaaa ctgccatcaa caagctgcca aacggaacag 3806881 acaaaaagaa ccttcaaaaa cgcttagacc aagtaaaacg atacatcgcg tcaaagcaag 3806941 cgaaagacaa agttgcgaaa gcggaaaaaa gcaaaaagaa aacagatgtg gacagcgcac 3807001 aatcagcaat tggcaagctg cctgcaagtt cagaaaaaac gtccctgcag aaacgcctta 3807061 acaaagtgaa gagcaccaat ttgaagacgg cacagcaatc cgtatctgcg gctgaaaaga 3807121 aatcaactga tgcaaatgcg gcaaaagcac aatcagccgt caatcagctt caagcaggca 3807181 aggacaaaac ggcattgcaa aaacggttag acaaagtgaa gaaaaaggtg gcggcggctg 3807241 aagcaaaaaa agtggaaact gcaaaggcaa aagtgaagaa agcggaaaaa gacaaaacaa 3807301 agaaatcaaa gacatccgct cagtctgcag tgaatcaatt aaaagcatcc aatgaaaaaa 3807361 caaagctgca aaaacggctg aacgccgtca aaccgaaaaa gtaaccaaaa acctttaaga 3807421 tttgcattcc aagtcttaaa ggtttttttc attctaagaa caccacacac aacctttttc 3807481 ccatccattg tacaggcttt tcatactatt gctatacagc catgaacagc ataaaatgaa 3807541 cgttattaca gttatcacca catatggcgg gattgtgact gggcaggcag gcaagaccca 3807601 atgatgcaaa gggagtatta atgcctaaaa aacagggcat tttaactctt cttttcgtgt 3807661 tgggctcata acggcgcctt ggacaacccc ctattctcat gctccgtcgt cgacgcgggc 3807721 atttttgtca ttttcagccg gtatttctca cttttttcat tttgattgtc aacttttcat 3807781 ttgatacgat gaacaagccg acttttcttc agcaaaggag gttttaattg cttgcataaa 3807841 gagattgcaa aagaattact gctgctcgca ggaggaaaaa acaatattat cagcatcagc 3807901 cattgtacga cccgtcttcg ttttgatgta aaggacgaga cgaaaattga tatacatgcc 3807961 attgagaacc tgcaaggtgt gcagggcacc tttttccgct atgggctttt ccagattatc 3808021 ttcggagcag gcgtcgtcaa caaaatatat aaagaagtcg ttcatgtatg ggagaccgcg 3808081 ccttctgaag agcctgtcca ccagaaaaaa gccagccgga agctgaaccc tgccgcagct 3808141 tttgcgaaaa cactgtccga tatttttgtg ccgattattc cggcaataac agcaagcggc 3808201 ctgctcatgg ggctgatcgg catgattaag gtgtttcatt ggttcgctgc cggcagccca 3808261 tggattaaaa tgctcgacct cgtgtccagc acagccttta ttttactgcc gattttagtc 3808321 ggcttcagtg ctgcacggca atttggcagc aacccatacc taggggcagt gattgcaggg 3808381 cttttgacgc atcctgatct gctggacccg tctatgctcg gcagcaaaac cccgtcttct 3808441 ttagacatat gggggcttca tatcccaatg atgggctatc agggttccat gataccgatt 3808501 cttctttccg tttttgtcat gagcaaaatt gagaagctat taaaatcgat tgtgccgaag 3808561 tcgcttgatg tcgtgatcat tccctttatt acggtcatgg tgacagggtg cctcgcgctg 3808621 attgtgatga atcccgccgc gtccatcatc ggccagatca tgacacaatc gatcgtctat 3808681 atttatgatc acgccggcat tgctgccgga gctcttttcg gcggcatcta ctccaccatc 3808741 gtcctatctg gattgcatca tagcttttat gcaattgagg caacgctgct tgctaatccg 3808801 catgtcggtg tcaacttttt agtgccgata tggtcgatgg cgaatgtggc ccaaggcgga 3808861 gcggggcttg cggtattcct caaaacgaaa caatcaagcc tgaagaaaat tgcgctcccc 3808921 gcttctctga ccgcgttttt aggcattgtt gagccgattg tattcggggt aaatctcaaa 3808981 ttgatccgtc cctttatcgg agcagccatc ggcggtgcta ttggcggagc atacgtggtt 3809041 gcggtacaag ttgtggcaaa ttcctacgga ctgacaggca ttccgatgat ttcaatcgtg 3809101 ctgccgtttg gcgccgctaa ttttgttcat tatatgatcg gtttcttgat cgcagccgtc 3809161 tctgctttta tagctacatt gtttctcggg tttaaagaag agacagaata actggattta 3809221 ttcgatttca ttcataaaac gggggatgaa aggacaaaaa agctatgaaa attaaaagaa 3809281 tcttaaatca taatgctatc gtcgtaaagg atcaaaatga agagaagatt ctcttgggtg 3809341 caggaattgc gtttaacaaa aagaagaatg atattgtcga tccgtcaaaa atagaaaaaa 3809401 cctttatcag aaaagataca cctgactata agcagttcga agagatttta gaaacattgc 3809461 ctgaagacca cattcagatt tctgagcaaa ttatctctca tgccgaaaaa gagctgaaca 3809521 tcaaaatcaa cgagcgcatt catgtcgctt tttcagacca tctttctttt gcaattgaac 3809581 gcctgagcaa tgggatggtt atcaaaaatc cgctgctgaa tgaaatcaaa gtcctttatc 3809641 caaaggagtt ccagatcggc ttatgggcca gagcactgat taaagataaa ctggggattc 3809701 acattcctga tgatgaaatc ggcaatatcg ccatgcatat ccacacagca agaaacaatg 3809761 ccggcgatat gacacaaacg cttgatatta caacaatgat ccgtgatatt atcgagatta 3809821 tcgaaattca actgtctatt aatatcgttg aagataccat ctcttatgaa aggctcgtga 3809881 cccatctccg ctttgccatt cagcatatca aagcaggcga atccatttac gagctggacg 3809941 cagaaatgat tgacatcatt aaagagaagt ttaaggatgc cttcctgtgt gccctaagca 3810001 tcggcacctt tgtgaagaag gaatacggct ttgagtttcc tgaaaaagaa ttgtgctaca 3810061 tcgccatgca tattcagcgg ttctaccaac ggtcagtcgc acgctgagac aaacaaaaaa 3810121 cgcttttgat catctcaaaa gcgttttttt atctgattta ttggttgatc gccggattcc 3810181 caatcgtatt ccacttcgta taggacatgt aatggaaata ctcatcgcga tacggatgtt 3810241 ttgtattgga gttccaaggc ttttctccgc cgcagaagtg cacgattgcc gggttttctc 3810301 ttgtttcatt atattgcttc cgccctaaca gagtcgatgg ggttttcagc tttaacatga 3810361 tataggtttg agcgttccag cgcggatgaa gttcatacca ctgatcatac aagatcgcat 3810421 tcagtgcatc ttggtcatgc agcacaagaa agtcttcgtc tgggtgttca ttgataaagt 3810481 tgatgacttt ttctgtgatg ttttgctttc tccaagactc aaaatcaata atcatgatac 3810541 ctgagttaaa atacttccct gtatcagtga cgttcatttc tttcaggcgt tcatgctgcc 3810601 ccgcatcctc aacagcggct acggtgtatg gcgcaatgtc taagtcccat agcttagaaa 3810661 tatcctctag gacaagcgca tcacaatcga tgtaaatcat tcgtttgatg ctttcatcct 3810721 taattaagtc gggaatcgaa atgcggtaat acgcggcttt tgtaatatgg ctgctctcaa 3810781 ccgcatgttc atacatgttg gtatccactt ctaaaaactc aatcggcact ccgaatttca 3810841 aagtggtttc ttccagtctt tttttgttat caggcttaat tccgccatca atgacgtata 3810901 attttacctc tctctcctga tccatgttag tcaataaaga aacgaacatc ccacctaaat 3810961 gacgagcata attatcatct gcgcatgata cgatatgcat gatttcatct ttcctcaatg 3811021 gtattcatct ccctttttgt tgtacaagtt acataccctt tttcaaaaaa ataaacacgt 3811081 tctccgacat ttttttaaac agaatgtgtg atacaacaaa aaaggtgtca ttttttgaag 3811141 atgcgataaa gccaataaag aatgaaaaag cttgcgattg tgatggcttc agccgagacg 3811201 atataccacg gccatggccc gagaacatct aagagagagg aaccgcccgg ttttttcgtc 3811261 aaatacatat aattcgcgcc aagccagcga tcaatcagaa aaatacagac gccgtacaca 3811321 ttaacaagca ggactgtcac ccataacgag cgctggccca ttctgtaggt gccaatcaca 3811381 gccatcagca gacaggataa aaacacagac ccgtgagaaa taaaaaagag gatatatcgg 3811441 atatgcggaa atgaaaacat accgaggtca ggagtggcaa gagcctgaat cgaactgccg 3811501 atgccgacaa aaaacaaaaa cacaaacagc tttctgcttt ttgtcactaa cataatagct 3811561 gacaaataca ccgacaggtc actaagctgg agaggcaatg aagtgcgcac cgaccacctg 3811621 tccgtggcga ccatccatat ttgatagccg atttgcgaac caagcaaaag aaacacaaac 3811681 agagaacgca aaaaccggct ggccctcggc tgcttgacct catcttggaa caaaaacaac 3811741 agaatggcca aaagggagat aatcgctaac gtcactacat gctctgtcga aaacagatga 3811801 aacggatcat gcttatagtc ggattgaaca tatttttgca aaactgcacc cccgttttcg 3811861 ggtttttgtt tattttggcg ttgtttgggc tttttttatt caaccgatat atgggcttga 3811921 agttcacacc agactctgtt aaaattcgtt tcatagctaa tgattctgat aatttaaggc 3811981 aggcctaaaa aatggaacgt tcacatcaac atcagcagct tcggaaggaa gaacacgata 3812041 cactttctaa gctcaaacaa atgcccgtcg agtcactcaa cctggaagcc atttcgatcg 3812101 ctacgaatct gtatcggtct gcacaaaggc tccgtgtcaa aatggagact gaggttcttt 3812161 ctacctataa cctttcttgg accgctttct ccattcttta tgatctatgg gtatggggag 3812221 cgctcgaaac gagaaaaatc gctgagctgt cagggatatc tacagctaca gcaagcaacg 3812281 tgatcaaaac gctcgaaaaa aagagttttt gccgtaaaag catcgacaca agagatcggc 3812341 gactcgtgtt tgtctcaatc accgattccg gcaaacaagc gatcgaagaa ctctacccgg 3812401 agtttcacaa aggggaaaca gagctcattg cgggaatgac gaaggacgaa cagaaaatat 3812461 tgacagggct gcttagaaag gtagctgaca atcttcatac aacataagct ttgacgggaa 3812521 tccagtagcg gtttgtctcc ctgtttcaga gagccggcgg taggtgcgag ccggcgcaca 3812581 ggcaaacgtg aattacctcc ccaagctttc tttgtgaacc ttagtagcaa agaacgggaa 3812641 accgttattc gaatgagcgg aagacaatgt cttcaaccag ggtggtaccg cgtgcattga 3812701 gccacgtccc ttattgggat gggctctttt ttgtgtttgt aaaaaaggag gaaaaatgat 3812761 gagaacattt gagcagctca cagcgtcaca acaaaaagag gtagaaagac agcttcagct 3812821 atacatgaca ggcgcccacg aagtcatacc gccggaggaa ttaaaggcaa agctcgtgaa 3812881 atcaatttcc acgggcacgc cgcttaaaat taagctcgga ttagatccgt ctgcaccgga 3812941 tgtacatttg ggccatacgg ttgtgttaaa taagcttcgc caatttcaag aaaacggcca 3813001 cattgtccag ctgttaattg gggatttcac aggaaaaatt ggtgatccga ccggaaaatc 3813061 ggcagccaga aagcaactga ctgatgaaga agttcagcac aatgccaaaa cctactttga 3813121 gcaattcgga aaagtgcttg atccagaaaa agtcgagctt cactataact caaaatggct 3813181 gaaaacattg aatctagaag atgtcattga attagcaggg aaaataacgg tagcccgcct 3813241 gatggagcgc gacgactttg aagaacgcat cgccatgcaa aaaccaatct cactgcatga 3813301 attcttttac ccattgatgc agggctatga ttctgtcgtt ctcgaaagtg atattgaatt 3813361 aggcggaacg gatcagcatt tcaatgtcct catgggacgg catttccaag aacgatacaa 3813421 caaagaaaaa caagtcgtca tccttatgcc gctcttggaa ggcttggatg gcgtcgagaa 3813481 aatgtcgaag tcgaaacaca actacattgg cattaacgaa catccaaacg acatgtacgg 3813541 aaaaacgatg tcactgcccg acagcctgat gaaaaagtac atccacttgg cgacagactt 3813601 agagcttgaa gagaaaaaac agctcgtaaa agacttagaa accggcgccg ttcatccgcg 3813661 tgatgccaaa atgcttttag ccagaacaat cgtccgaatg tatcacggag agaaagcagc 3813721 agaagctgcc gaacactcgt ttaaaacagt ctttcaggaa aacagcctgc cggaagatat 3813781 accggccgta aactggaaag gcgaaaaaac gatagcgatg attgatctgc tcgtcaagct 3813841 aaagctcctc tcttcgaaga gcgaggcgcg ccgcatgatt caaaacggag gtgtacgcat 3813901 cgacggagag aaagtaacag atgttcacgc caaagcagag ataagagaga atatgatcat 3813961 ccaagtcggc aaacgcaagt ttttaaagct ccaataatct gatattccga aacgcttatg 3814021 acccttcatt cataagcgtt tttttgcagg tataaagcac tgtcttttca aaaacgctct 3814081 ccatcttgca ggaaactcct ttagcatccc gaaatattcc ccaaccatac atttagggga 3814141 ggtttatttt tgatgaaaaa gcttttgact gtcatgacga tggctgtttt aactgccggc 3814201 acactgctct tgccggcaca gagtgtcacc cctgccgcgc acgctgtaca aatatcaaat 3814261 agcgagcgcg agcttccatt caaagcaaaa catgcgtact ctaccatttc tcagctaagt 3814321 gaagcaatcg gccccagaat agccggaact gcagctgaaa aaaagagtgc cctattgatc 3814381 gcctcatcaa tgagaaaatt aaagcttgat gtgaaggttc aacgattcaa cattcctgac 3814441 cggcttgagg gtacactgtc ttcagcagga cgcgatattc ttctccaagc ggcgtcgggc 3814501 tcagctccga ctgaggaaca agggctgacg gccccgcttt acaatgcggg attgggctat 3814561 caaaaggact ttaccgctga cgccaagggc aaaatcgcct tgatttccag aggagacctg 3814621 acttattacg agaaagccaa aaatgccgaa gccgccggag cgaaagctgt catcatttat 3814681 aacaacaaag aaagcctcgt gcctatgacg ccaaacctgt cgggaaataa agtcggcatt 3814741 ccggtcgtcg gcattaagaa agaagacggc gaagcactta cccagcaaaa agaagccacc 3814801 ttaaaactaa aagcattcac aaaccaaacc tcccagaata tcatcggaat caaaaaacca 3814861 aagaacatca aacatccaga cattgtgtac gtgaccgccc attacgacag tgttcctttt 3814921 tcgcccggag caaatgacaa cggctcaggt acctctgtta tgctggagat ggcgcgtgtc 3814981 ttaaaaagcg ttccatctga taaagaaatc cgctttatcg ctttcggcgc cgaagagctc 3815041 ggcctgctcg gctcctctca ctatgtagat catctatcgg aaaaagagct gaaacgaagc 3815101 gaagtgaact tcaacttaga tatggtaggc acaagctggg aaaaagcgtc tgagctgtat 3815161 gtcaacacat tggatggcca atctaactat gtttgggaat ccagccgtac ggctgctgaa 3815221 aaaattgggt ttgacagcct gtctctgaca cagggaggat catctgatca tgtgccattc 3815281 cacgaagccg gcattgattc cgctaacttt atttggggag acccggaaac agaagaagtt 3815341 gagccgtggt atcatacccc tgaagactcg atcgaacata tcagcaaaga acgcctccag 3815401 caagcaggcg atcttgtgac agccgctgtc tatgaggctg tgaaaaaaga gaagaaaccg 3815461 aaaaccatta agaaacaaat gaaggcgaaa gcatctgaca tttttgaaga tatcaaataa 3815521 aaaaagacgg cacttgggtg ccgtcttttt taatccactt ctttcttaat ccccagcatt 3815581 ttctcatcta ggtaatgggc aatctccgcg gcttctttca gctcatctgt taattgctta 3815641 ggaacgtcat tgttcaattt ataataaatt ttatgttcaa ggctcgccca gaaatccatc 3815701 gcgattgtcc ggatttgaat ttctgctttg acgtattcca cacggttcgt taaattcaca 3815761 ggcatctcaa tgattaaatg caggcttcga tagccattcg gtttgggtgt ctggatataa 3815821 tcctttacct ttacgattct caaatcttca tgctgcttca acacattcac gacattataa 3815881 atgtcagaaa taaaggaaca gatgatgcgc acgccggcaa tgtcgtgaat atgctccttc 3815941 atttccttcg tcgtaatctc acagcccttt ctcattaact tattcacgat gctttcaaag 3816001 ctttttacac gggattttgt atgttcaatc gggttgtgtc cgtgaatgag gttatattcc 3816061 tggctgataa ttgagaactt tgtatcgagc gcatctagcg caaatttata aactaataac 3816121 tcatttttcc aatcttccat tactgttttt aaatcgtcca tatgtgttac agataaatcc 3816181 atgttcgtca tctcctttaa cggaacttta tccgctgtcc atgtactaga cgtccctgtc 3816241 tgctgcaagg ttctatgaat ttttttacaa aatgcggtcg attgtaacaa aaaaagaccg 3816301 catgaaacga gcggtctttt ttattatcgg aaatagctga tcaataatcc gatcgagagc 3816361 aggaatccga aaaatgtatt tgtttgggct gttgatttca ttgcgacaat catattcatc 3816421 ggcatttcgt tctggacgaa gcccttcact gcctgaaccg gcttaggcac gctcaaaaag 3816481 acgacaaaca gccatgggct tgcggcaccg gtaataacca agccgacaac ccagatataa 3816541 gcgacggcaa acgacgcagc taacagagta acagctccct tatgccccat caaaatcgcc 3816601 aatgttttgc gtccgccttt tttgtcctct tcaatatcac gaatgttgtt cgacaggtta 3816661 atcgcgccga caagaatcgc aatcgggatg gaaatcaaaa tgctctgcat attgatctta 3816721 tctgtctgaa tgaaaaacga aatcagcaca aacaccgaac ccatgcaaat gcctgagaat 3816781 aattcaccga acggcgtgta cgcaatcggc agcggcccgc ctgtatacag gtagccgatc 3816841 gccatgccga caaggccgat cagcgcaagc caccagctgc tgctggcaca aatatagaca 3816901 ccgagcaaaa tggcaatccc gtatgaggca agagctaatt gcaaaatcgt tttaggcttc 3816961 attccgtggc gtacaatggc ccctccgatt ccgactgatt ctgctgtatc taatccgcgt 3817021 ttaaaatcat agtattcatt aaataagttc gtcgcgatct ggatccatag gcaagaaaac 3817081 agcatagcca aaaacagcag cagatcaacc ttcacataaa acatcgccaa aacggttccg 3817141 agcagcacag gcacaaacga tgcggttaac gtatgaggac gggttaactg ccaaaggatc 3817201 tgccccatgc tttctttttg cggcgctgtc tgaccctcac ccttatttgt ttggttcatc 3817261 ttcctcttcc tttctattaa aaggcttact ttttttcagc cggcagctta ataaaaaact 3817321 ccttttgctt ccttatctat cataatgact tctcccttat ttcacaagat accgcaagaa 3817381 ggcgttttct ttcttattat acgcttctcg ccctgatttc attaggtttc tgctttcact 3817441 tgaacgaaca ggtacagaaa aattttttta agtacattac actttttaaa agttaaaaag 3817501 atcttttgac tccaggtatc ttttccttta ttatgaatca gctcgaaaca ttccattctt 3817561 gcccttgcag gtataaagat tcattttcaa aaacatacgc cgatatatta atttgaggga 3817621 gattagggaa aaaatgaaac tttttgagca tctgatcgtc aaataatcat gtgattgtcg 3817681 aaaaaacggg aagggaattt ttgatatgct gcaattaatg aaacagctgt atgaaaaacc 3817741 cgctgtcaag tggacatgtc atacaggctt ttatttgatg atactgcttg ttttgttttt 3817801 tatgtatggt tttcacaccg cgaataccgg ttcatatatt tataacgatt tctaattgga 3817861 gagagaataa ctatgaaact tttacatgct attcaaacac atgcggaaac ttatccgcaa 3817921 accgatgcct tccgctctca aggccagtcg ctcacgtatc aggaattatg ggagcagtct 3817981 gaccgcgcgg ctgccgcgat ccaaaaacgc atttctgggg aaaagaaatc tcctatcctt 3818041 gtgtacggcc acatggagcc gcacatgatc gtttccttct tgggaagtgt caaagcggga 3818101 catccttata ttccggttga cctgtctatt ccgtccgaac ggattgcgaa aattatcgaa 3818161 agctctggag cagaattgct gatccatgca gcaggactct caattgatgc agtcggccag 3818221 cagattcaga cagtttctgc ggaagaactg ctggaaaacg aaggcggctc tgtcagccaa 3818281 gatcaatggg tcaaagaaca cgaaacgttt tatatcattt acacttccgg gagcacagga 3818341 aatccgaaag gcgtgcagat ttccgctgcg aaccttcaaa gcttcacaga ctggatttgt 3818401 gcagactttc cagtcagcgg aggaaaaata tttttaaacc aagcgccgtt ctcatttgat 3818461 ttgtctgtca tggacctata tccgtgcctt caatcaggcg ggactttaca ttgcgtgaca 3818521 aaggatgctg tgaataagcc gaaagtctta tttgaagagc tgaagaagtc cgggctgaat 3818581 gtgtggacat caacaccttc ctttgtgcaa atgtgcctga tggatccggg tttttcacag 3818641 gatctgctgc ctcatgcgga cacatttatg ttttgcggag aggttcttcc ggtttctgtg 3818701 gccaaagcgc tgcttgagcg ttttccgaaa gcgaagattt ttaatacgta cggcccgact 3818761 gaagcgacag tggctgtcac atcggttgaa attacgaatg acgtcatcag ccgcagcgaa 3818821 tcgcttccag tgggcttcgc caaaccagat atgaacattt tcattatgga tgaagaggga 3818881 cagccgcttc ctgagggaga aaaaggagaa atcgtcattg cagggccgag tgtaagccga 3818941 ggctaccttg gtgagccaga gctgacggaa aaagcgtttt tctctcatga aggccagtgg 3819001 gcataccgaa ctggcgatgc cggctttatt caagacggtc agattttctg ccaaggacgt 3819061 ttggattttc agattaaact tcacggctat cgaatggagc tggaggaaat cgagttccat 3819121 gtcagacagt cacagtacgt tcgttctgct gtcgtgattc cttatcagcc aaacggaaca 3819181 gttgagtatc tgatcgctgc tattgtgcct gaggagcatg agttcgagaa ggaattccag 3819241 ctgacaagcg ctattaaaaa agagcttgcc gcttctcttc cggcatatat gatcccgaga 3819301 aaatttatct atcaggatca cattcaaatg acggctaacg gcaaaattga ccgaaaacgc 3819361 attggcgaag aggttcttgt atgacgcctt acagctcgtt tttattcttt atactgcttg 3819421 gcattcttct tctgccgacg atcattctcg gcttaaacgg aaaaagattt caagcataca 3819481 acatgttcat atctatcatt atattggctt taattttttc gcacgactta cacggggtca 3819541 tcgcgctgtg cctgtttaca atatggcagg tgctcctgat cagcggctat ctggcatacc 3819601 ggcagaaagc gaacagcggc tttgtctttt gcggagctgt tatcgcgtct attctgcctt 3819661 tatttctgtc aaaaatatgg ccgtttcttt cacacccgca gccgcatcat ccgccgcata 3819721 acctgatcag ctttttaggg atttcatatt taacctttaa aggcgttcag ctgattatgg 3819781 aagcaagaga cggactgctg aaagaacagc tgccattgca ccgtctgctg tatttcatcc 3819841 tgtttttccc gacgatttcc tccggcccga tcgacagata ccgccggttc gtcaaggatg 3819901 aacagaaggc ttggacgaaa gaagaatacg ccgacctgct gtatacggga atccataaaa 3819961 tcttcatcgg tttcctgtat aaatttatta tcggctacgc gatcaatacg tacttcatca 3820021 tgaatcttcc cgcaatcacg cacaataaga ttcttgggaa cctgctgtac atgtacggct 3820081 acagcatgta tttattcttt gatttcgccg gctacacgat gtttgccgtc ggggtcagct 3820141 acattatggg cattaaatca ccagaaaact ttaataaacc gtttatcagt aaaaatatta 3820201 aagatttctg gaatcgctgg catatgtctc tgtcattttg gttcagagat tatgtgttta 3820261 tgagattcgt attttggatg actaagaaaa agtggatcaa aaaccgtatg gccgtctcaa 3820321 acatcgggta tttcctgctg tttatgctga tgggggtttg gcacgggctc gcgccgcaat 3820381 atatcattta cggcctctat cacgccgttc tgatgacgtg ttacaacttt ttcgagaagt 3820441 ggaataagaa atataaatgg ctgccgtcca accgctggac aaccattctc gctattgtga 3820501 tcacattcca tttcgtttgc ttcgggtttt atattttctc aggaaaacca tttcatcacc 3820561 accattaaag gagattagaa agctatggat tttaaacaag aggtattaga cgttttagca 3820621 gaggtttgcc aggatgacat cgtaaaggaa aatcctgata ttgaaatttt tgaagaaggt 3820681 ttgcttgatt cttttggaac agtagaattg ctgcttgcga ttgaaaaccg ttttgatatt 3820741 ttagtgccga tcactgaatt tgaccgggac gtttggaata cacctaacaa cattgtaaat 3820801 cagctgtctg agttgaaata atgaaaaagc gttttttcgg tccaattatt ttggcgttta 3820861 ttctattcgc aggcgccatc gcaattccat cttcatggct gacaggcttc atcaccgata 3820921 agcgtgtgaa agagtcagca acagccttga atccgagtat gtttcaaggg ctatatttac 3820981 aagatcagat gctcaaagat ccgacatatc ttccgattta cgggtcttct gagctttctc 3821041 ggctggacga gttccaccca tctaattatt ttcaggtaaa caatgaggga ttcacgccat 3821101 accttgtcgg caaaggcgga tcccagtcat tgattcattc tttaaacttc gctgcccaca 3821161 tggatcagct gaagggcaaa aaaatcgtat tcatcgtgtc tccgcaatgg tttattaagc 3821221 gcgggtctga tgaacagcat ttcgcgccga actattctgc gctgcaaggg cttgatttgg 3821281 catttaacga tcagatcgat cctgaaatta aaaagaaaat gatgaaacgc atgcttcgct 3821341 ttaaggctgt gcaaaacgat gccattcttt ctgagctgta caaagcaatg gtaaacggtc 3821401 agacgtggaa agtgaacgcg ctgaagccgg cggcgaaagt gtattacagc atgctggaaa 3821461 agaaagatct gtattattca acgacagaat catccgggcc aaagcgctat atctcgcagt 3821521 cagtaaagga taagtcatgg tctgaattga ataaactagc ggatcaatcg ggcaaacgcc 3821581 actccggttc taacgatttt cacatcgaca accctgtcta taaaaagctg aagccgaaag 3821641 tgcctaagct gaaagggaaa aacaaaggaa gatcgtatgc ggtgtcaccg gaatatggcg 3821701 actttgaaat gatgctcgat atcctgaagg atgcgggcgc agagcctatg tttgtcacca 3821761 ttcctgttaa cgggaaatgg tacgattaca cgggcttccc gaaaaaagga cgcactgact 3821821 attacaaaaa ggtaaataaa caaatcagag cgaagggctt ccaggttgct gatttctcag 3821881 ggcatgaata tgacccgtat ttcatgaaag acaccattca catcggctgg aaaggctggg 3821941 tgtatgtcga taaagcaatt gacgaatttt ataaaaccgg aaaagtcact tcatcctgag 3822001 catctcatag gacgcggctg catatttcct gctaagattt gtaatagtaa aggaatcaca 3822061 gccaacttaa ttaagaggtg ttacatccaa tgaagatgac aaataatacg gttttaatca 3822121 cagggggttc tgctggcatc gggcttgaac tggccaagcg cctgctggaa cttggcaatg 3822181 aagttatcat ttgcggacgc agcgaagcac gtcttgcaga agcgaagcag cagctcccaa 3822241 acatccatac aaagcaatgt gatgttgcag accgttcgca gcgggaagca ttgtatgaat 3822301 gggctttaaa ggaatatccg aacttgaatg ttctcgtcaa caacgccggc attcaaaagg 3822361 aaattgactt taaaaaaggg acagaggagc tttttgtgga cggtgatgaa attgaactta 3822421 atttccaagc gcctgtccat ttatccgccc ttttcacacc tcatttgatg aagcagcccg 3822481 aggcggcaat cgttcaggtc acatccgggc ttgcgtttaa cccgttagct gtttatccgg 3822541 tgtactgcgc aacaaaagcg gcacttcact cgttctcgct tacgctcaga caccagctcc 3822601 gcgacacgag cgtggaagtg attgaaatgg caccgcctat ggtggacacg ggcttaaacc 3822661 aaaaatcacg cgataaacaa ggcctgacgt accggggcat ttcatctgaa gaatatgttc 3822721 aatatttctt ggacggcttg aaggaaggca aacaggagat tacaaatgaa cgtgttgaag 3822781 gtcttcggga tgccactcgc gccgattatg acaggttatt cgagcaaatg aacacgcagg 3822841 agaattaatt tctcctgctt ttttcatatg aatttcttac aaatttgagc aaacctattg 3822901 cgattatttg ttgaaggtat acaatagaat ataattattt tcaaataagt ttgataatat 3822961 aaacaattta acagcaggga gattgaccat gactaaacaa acaattcgcg ttgaattgac 3823021 atcaacaaaa aaaccgaaac cagacccaaa tcagctttcg ttcggaagag tgtttacaga 3823081 ccacatgttt gtaatggact atgccgcaga taaaggttgg tacgatccaa gaatcattcc 3823141 ttatcaaccc ttatcaatgg atccggctgc aatggtctat cactacggcc aaaccgtgtt 3823201 tgaagggtta aaggcttacg tgtcagagga tgaccatgtt ctgcttttca gaccggaaaa 3823261 aaatatggaa cgcctgaatc aatcaaacga ccgcctctgc atcccgcaaa ttgatgaaga 3823321 acaggttctt gaaggcttaa agcagcttgt cgcaattgat aaagactgga ttccaaatgc 3823381 ggagggcacg tccctttaca tccgtccgtt catcatcgca accgagcctt tccttggtgt 3823441 tgcggcatct catacgtata agctcttgat cattctttct ccggtcggct cttattacaa 3823501 agaaggcatt aagccggtca aaatcgctgt tgaaagtgaa tttgtccgtg cggtaaaagg 3823561 cggaacagga aatgccaaaa ccgcaggaaa ctatgcttca agcttaaaag cgcagcaggt 3823621 agccgaagag aaaggatttt ctcaagtact ctggctggac ggcattgaga agaaatacat 3823681 cgaagaagtc ggaagcatga acatcttctt caaaatcaac ggtgaaatcg taacaccgat 3823741 gctgaacggg agcatcctgg aaggcattac gcgcaattca gtcatcgcct tgcttaagca 3823801 ttggggcctt caagtttcag aacgaaaaat tgcgatcgat gaggtcatcc aagcccataa 3823861 agacggcatc ctggaagaag ccttcggaac aggtacagca gctgttattt ccccagtcgg 3823921 cgagctgatc tggcaggatg aaacactttc gatcaacaac ggtgaaacag gagaaatcgc 3823981 aaaaaaacta tatgacacga ttacaggcat tcaaaaaggc gctgtcgcag acgaattcgg 3824041 atggacgacc gaagtcgcag cgctgactga aagcaagtaa gaaaaaagcc ggcccattac 3824101 aggccggctt tttttacgct tcaattttgt tgaaaaactg cggcagatac gctttgtgcg 3824161 cctctagcat ttcgtctaaa atctgtttgg ccacagtatc ggacgggaca agcgggttaa 3824221 tcgtcatggc aaggagcgca gtttgatagt cacctgtaac tgccgcttct gccgcgacac 3824281 gttcaaagga tttgatttgc tggacaaggc cgcggacaga caccggcaag tcgccgacag 3824341 caattggctt agggccggtt ttcgtcatca cacagttcac ttcaactgcg gaatcgtctg 3824401 gaatactcgc tattgcacca ttattgatcg tgttcaccgg ctgaatgtca tgtttatcat 3824461 tataaatgga gctgattaag ttacatgctg catcactgta gtaagctccg ccccgttttt 3824521 ccagctgcgg cggtttgatc gcaaggtttg gatctttata aagctcgaac agctcttttt 3824581 cgaccttctg tacgacttca gcgcgggtgc cctccgtttg tgatgcttcc agttcgtgct 3824641 ccagcatctc ttttgtttta aaatagtaac ggtgatagcc gcaagggatg acattgagcg 3824701 cttttaagaa atccggttcc cattcggcgc ctgagatatt tttcatcgtc atcgcgtttt 3824761 tcgggtcgcc catcgcctcg atgacttgct ccttcacact tacgccgtcc aagaaaacat 3824821 ccagcccgaa taccatatgg ttcagtccgg caaattggac ttctacgcgg tccacatcta 3824881 catcaagcgc tttggctacg cccattttga tgccgattgg aacattgcaa agaccgacga 3824941 ctttcttcag gttggagtag cgaagcaagg cttctgttac catgccggca gggtttgtga 3825001 agttaacaag ccaagcgttc gggcaaagct cttctatgtc ctttgcgatc tcaaggatga 3825061 ccggaattgt gcgcaatcct ttaaacagac ctcccgggcc gtttgtttcc tggcctatca 3825121 ctccgtattt tagcggaatg cgctcatcct ttgctcttgc ctgcaaaagt ccgacgcgga 3825181 attgggtcgt gacaaagtct gcgtctttca gcgcctttct ccggtcgagc gtaagatgaa 3825241 tgtcaatcgg gacgccagct ttttcaacca tccgtttggc gagtgtgccg acaatattca 3825301 gcttttcttc gccctcgggg atatcgacaa gccataattc acggacaggc agctcatcat 3825361 accgtttaat gaacccctcc actagctcgg gcgtatagct tgaacctccg ccaatcgtta 3825421 caatcttcaa tccttttgtc atatgcttgc tcccctttgc tcggtgattt tttcatataa 3825481 ctcaatgatc tctgcagcca tatccttcac tgtcattgca ttcattaaat gatcctgtgc 3825541 atgaaccatc agaagcgtca tttccgtctt ttctccgccc gcttcatttt ggatcagctc 3825601 tgtctgataa tgatgggctt ttgacaattc ttcagcagcg tcttgaagct ttttccgcgc 3825661 ttcttctgcg tcaccgcttt tcgcagcggc aatggcctcc attgcggagc tcctaccgtt 3825721 tcctccgtga aggatgattt gaaaaatgat ttgttccatt tcctcattca cgcgattcac 3825781 ttcctttctc tacagagccg cttctttgtc atctgttgct gcaggcgttt ggaccagctc 3825841 cagatcgttt tcttctttca gcttctgctt atcccacatt ctgaagaatg gatagtagac 3825901 aacaaaggac acggcaatat taatggcttg catgaccgcg cctgagactt ttcctcctgt 3825961 cgccaagtag cctgaaaaga tcggcggcat ggtccacggc actgcgatac ccgccggttt 3826021 ggcgacaagg ccggtgctca ttccgatgta cgtgagtgtc actgtgacaa gcggcgtgat 3826081 gataaacgga agtaagagca ttgggttcat gacgatcggc attccgaata taatcggttc 3826141 gttaatattg aagatggccg ggccgaccgc aagcttcccg agctgcttca tttgtttgct 3826201 tcgggcgcgc aggaacatcg tgacaaccag tgccaatgtg gcgccgcttc cgccaatatt 3826261 gacccagata tcgaaaaatt gctgggtgaa aatcttagga agctcctcac cggcttggaa 3826321 tgcgatccgg ttggcatcca ttgcgccgta ccaaatcggt gccatgacgc cgccaacaat 3826381 gtttgcaccg tgaaggccgc aggcccataa aagcattttg acggcttcgg cgacaaggct 3826441 tcctccaagg cttcctccca gaatggaaag cggagtcccc aataaaacgc ttacaatatt 3826501 atgaaggctt tcaaacggtg tcgcttcaac aatcagccgg gctgcccaaa ttaggaagat 3826561 gacggcaaag ccggggatta acgcgacaaa tgacttgctt accgccggcg ggacaccgtc 3826621 cggcattttg aagactaaat tgcgctggat aataaggcgg taaatctctg tggacaccat 3826681 tgcgataatc atggcgacaa ataagccttt gcttcccatg agcgaaagcg gaatcccgcc 3826741 gccaaccatg atttctttcg tcgcgccatc cggcataaac ggcacttgat aaggtgttgc 3826801 taataaaaat gccgcaaggg aaatggctcc ggccgacaag gcatcaacac cgtatttctc 3826861 ggcgagccgg taggcaatgc cgaacgcggc gacaagaccc ataatttcaa aggtcgcgtc 3826921 gactgggtag gccagttttt cagaccagga gctgccaaac gtttttgcca taaactcagc 3826981 gtatcccggg atcgggaggt tgccaatgat gaggaaaaag gaaccgatga taatcagggg 3827041 catcgtgagg atgataccat cacgcagcgc ctgcaaatga cgctgtcccg caattcttcc 3827101 cgctataggc atgacctttt cttctaagat ctgattgact ttattcacat agcccgcccc 3827161 tctctatgac acatgtccaa gctgttcagc tgatttcagc acttccgccc cattgcacgt 3827221 tccataatgg acggtattaa tgacgtctac cggaaccccc tttgactctc ctaatttttt 3827281 gagctgcgga agcatgtaac ggacttgcgg accgagaagc aatacatccg ctttatcgat 3827341 atgattttgt acagaatcgc ctgaaactgc ccaaatggta tagtcttttc cctgttcctg 3827401 cgcacttttt tccatcttgc tcaccagtaa gctagtagac atgcctgctg cacaaacgag 3827461 taatatattc atgtaaaaga ccccctagag tttgatcaat tttgtaatgt cctgctgttg 3827521 ctatcatcat attatgaaat cgctttcata aacactcagg gtttttccgc aggcaacgga 3827581 aaaaaggtat atacaggctg tcagctcagc attttttggt caaacacatc cgaaagctct 3827641 tgatatgaac ggcatttgat cagctggttc atcgccgccg ggtcatccaa aatgctgcca 3827701 agcagtttat acatgctttg taaatccgct ttgttctcct tttcgacaca aagcagacag 3827761 acaaattgaa ctcgctgact ctcccaatcg atcggttttt tgagcgtaca aacggcccaa 3827821 aacgttgttt tcgtctgcgg aacaagcggg tgcgggatgg caacaagatt gccaaaacac 3827881 gttggcgaca tgtcttctct ttcaaaaatg gaatctatga tttcttcatc ggcaaagccg 3827941 cattcgacca ctttctgccc taaaaattga atcacttctt cttttgagcg cagatcctcc 3828001 tgaaaaaaaa cgagttcttt ttttaggtag cgattggctt tttccttttc atcactcaga 3828061 atagattcta tttttgtaaa gtcagttccg cctaagatgg tgttaacctt cagtactggt 3828121 acagggagct cttttttaat cggaatggtg ctgatgacaa aatcaattga ttcgtaggac 3828181 atttgatcaa gactataata ctcagccgtt ccaagaatat cgagccgctt gccgaaatgg 3828241 gaacgcagtt tttcgcgcag aagctgggcg cttccggctc ccgatgcgca tacaatgata 3828301 cagcgtttcg gcgggctttc tgtttttttt cgttcaatcg cggcgccaaa gtggagagcc 3828361 aaatatccaa tttcgttttc atgaatctca atacccgttt gttcctttat cacgattccg 3828421 gcaatgatcc cggcttcaaa agcgagtgga taatgttcct tgatcgctgc cagcatcgga 3828481 tttcgaagat tcatgccgta tcggttgcgg ctgatcgccg gcttcatatg cagtgccaag 3828541 ccgattttca gctctttgtc atgcaggatg ccaagcttca gttcacgatc aacagctttg 3828601 atcatggcaa gtgtcagctg atcggtttcc tcttctattg aaaatgtgtc ctctccgcat 3828661 tgtgattgtg tcattcgttt tgtgccaagg agatgcatgg tgatgtaggc cgtctcgtct 3828721 ttcggaaacg taacggaaag ctttgattcc agctctttta cgatggcttc tgcagcctgg 3828781 tactcctttt gatgcaggat atgatccata tctttcggga aaagagaaac atagttttcc 3828841 gttctgatcc gtttacaggc gatagcgata tggataatga ggttattcag tcccatgttg 3828901 gacagaggga tgcggtcgtt tttcattttt ttcaagatgg cggaacggat gatctcaatt 3828961 tcttcttttg gcaaaatatc agccttttca tttaaaacat ctatctccgt ttctctttca 3829021 tcaacaatgt actccgccat gcagtacctc atctgcacct cgtccccgcg cagcttgaag 3829081 ccgtaattcg gacgtgtttc catgacgatg cggtaaggca gcagacgttt ctttacttcc 3829141 tttaaatccg tttggagtgt agattttgag ataaatagtt cttcagcaag ttcatcgagc 3829201 ttgagataat ggtccgccag cagcagacgt ttcataagat aggccattct ctcctccggc 3829261 aataccggca ggcccttttt ttgctgaaat tcatcttgca gcagtgttct gaatacttgc 3829321 tcgtcatcaa tgcggagctt gtagccggag cctcttacag attgtacaaa ggcaccgtgg 3829381 ccgcttagca caccttgaag ttcctttata tcattgcgga ctgtccgcgt cgttacgttt 3829441 aattgcgcgg caaaaaacga acttgtcacc ggggcttcag ccgccatcag caagcgcaga 3829501 atatcacgta gtcgcccatg aagcatgaga aaaacctcct aactagtaga tgcagggatt 3829561 cagtgaatag gcagaaagga tgatgaaggg atgcgaaatg tatataaatt ctataatgga 3829621 gagaatggca agtcaatgaa catccggagg actagaggga aaactgacct ataaaaaaac 3829681 agccgggatc agccggctgt tctagatgcg gacatattct tttgtttaga cgccttgcgg 3829741 tccttcatga tttttcgaac aatcgggtaa atgaccggcg cccatttgat aacggttttg 3829801 atcatctttt tcaaagctcc gattctccct tcttttttct caaccattcc cctgattgcc 3829861 tcttccttaa acatgctaac gcgacacgta cctgtttccc gtcacccaga aacgccatgg 3829921 ataatcgcgt gcctccccgc tgttgtcaat gccgatgcgc gggccggttg aaattgcttc 3829981 cggtgtgtac ccgctttcga tgtaaagcgg ctgttccgtg atccagcgtc cgtagtcatt 3830041 catcgtgacg ccaagcgctt tcgtcagctt tcctggtccg tttgtccatt ccctcggact 3830101 cctgcccggc cttctctcct ccattaacag ctggccttca tgcggctcaa tcgccctgat 3830161 taatactgct tgcgggacat cctcttccgc cgcaacgaca ttcagcaatg tatgggtgtg 3830221 catcacgtat gtatataccc gcccagcttc tgcaaacatg atctcagtcc gcttcgtccg 3830281 gcggttgtta aagctgtggg ccgctctgtc tccagccccc atataggcct ctgtttccac 3830341 aatatagcct gacgctgtgc cttcgtctgt ttcttttaca agaaggcagc ccagaagcga 3830401 tggggcaagc tcaagagcgg ttttttgata aaacgtgatg ggcagcggat ttttttctct 3830461 cgtcacgaat cgacctctcc ttttaccgat ttttgtacat tgtaccattc ccgaagcaga 3830521 tcaaaaaaaa cggctgtttt aaaatctttc cattcaggga atattgttac cgttcaaaaa 3830581 aggagggcca accattgaaa gatgatcatc aaaacaagca gcaccaatca aatgcccaag 3830641 ggagcgagga agcgttttct cataagacat ccgggaaaaa cgagtcagag gataccttaa 3830701 cgaataggca ggggcatcct gttactgaca accagaatgt gagaaccgtc gggaatagag 3830761 ggcctacaac acttgagaac tatgattttc tcgaaaagat cagccacttc gaccgggaac 3830821 gcatcccaga gcgggttgtt catgccaggg gagcaggtgc acatggatat tttgaagcgt 3830881 acggaagctt cggagacgaa ccgatttcaa catacacaag ggccaagctc tttcaggaaa 3830941 aaggcaagaa aacaccggca tttgtccgtt tttcaactgt gaatcatgga aaacactcgc 3831001 ctgaaacatt gagagacccg cgcggttttg ctgtaaagct atatacagaa gacggaaact 3831061 gggatttggt cggaaacaac ctgaaaatct tttttatccg cgacccgctg aaatttccgg 3831121 atcttgtaca cgcatttcag cctgatccag tgacaaacat ccaggatggt gaacgtatct 3831181 tcgatttcat ttctcaatct cctgaagcga cacacatgat caccttcttg ttttcgcctt 3831241 ggggcattcc ggccaactac cggcaaatgc agggttcagg cgtacatgcc tataaatggg 3831301 tgaatgagga gggcaaggcc gttctcgtga aataccattt tgaaccgaag cagggcatcc 3831361 gcaacctgac acagaaggaa gcagaagaga ttcaagggaa aaactttaac catgccacac 3831421 aggatctata tgacgcgatt gaaaatggcg attatccaga gtgggaagta tatgctcaaa 3831481 tcatgagcga tgatgagcat cctgaactgg actttgatcc tcttgatcca acaaaactgt 3831541 ggtataaaga cgatttccca tggaaaccga tcggcaaatt ggttctgaac aaaaatccgg 3831601 aaaactacca tgcggaagtg gagcaagctt catttggaac gggagtgctt gtcgacgggc 3831661 ttgatttttc agacgacaaa ttgctccagg ggcgtacgtt tgcctactct gatacgcagc 3831721 gctaccgtgt aggcgcaaat tacctgcagc ttccgatcaa ctcgccgaaa aagcatgtcg 3831781 ccaccaacca ggaaggcggg caaatgcaat atcgggtcga tagagcagaa ggacaaaacc 3831841 cgcacgtcaa ctacgagcca tccattatgg gcgggctgaa ggaagcgaag caagacggaa 3831901 aagaccatac gccgcatgtc gaaggtgatg taaagcgtga agcgattgac agaacaaaca 3831961 acttcggaca ggctggagaa acgtaccgga gatttactga atttgagcgg aacgaattga 3832021 ttacgaattt ggtgaatacg ctttctacgt gccgaaaaga aattcaggat caaatgattg 3832081 agaatttcac aaaagctgat cctgactacg gaaaacgcgt agcagaaggg ctaaaaaagg 3832141 tctccgaaaa caacagcaac gggccgatcg gcacaactga aacggaacag gctgcaaagc 3832201 aggctgaaca ggagagtcat ccgtctgatc cgtattaaca acagcgaaca gggctttttt 3832261 agaagccctg tttttttatt tttctattga aacgctttca ataattgtgt tgtacttgga 3832321 aggaaagggg tggagagata cgatggaatt acagcaggac ttgattcctc agaaaaaaac 3832381 aatcggcgct ttagatcacg ccgttttttt atgcatggta ttttgtttct ggttttcagg 3832441 ctatatttac gttcctgtat tcagtctgta tttggaggat ctgcactttt catatggcgc 3832501 aatcggcatc attctcggca gctacggggt cacgcaaatc cttctgcgat tcccgctcgg 3832561 ccttttgtca gacatcctgt tttccttgcg caagcaattg ttaattgccg ggttcggctt 3832621 ttccgtcctc agcagcctgc tttttctgat gtttgattct ttcttcttcg tgctggccgc 3832681 ccggcttttc gcgggaatca ctgcttctac gtgggtgatg gcgaccattt tatacgcaca 3832741 ttatttcaac aatggcaatg catcaaaagc aatgggcatc atgcagtttt ttaccgtcat 3832801 gcctcagttt gccagcattg tgttctgcgg gctcgccgca gcccatttag ggaggcaggt 3832861 tcctttttgg atggcgctgg cagcttctgc cgcaggtctg gtgatctgct gctttattca 3832921 ggatccgtct gctcctcccg caaaccgtgg caccattcgt gtcaatcagt acatcaaaga 3832981 tacattgcgg ctgccaaagc tgaagctttt caccatcctg tctatgacgg cccatgccgt 3833041 attatttatc acagtgtttg gttttacgcc gctttacatg aatcagctcg gaatgggcga 3833101 cgcggagctg ctttgggtga tgagcgcctt tttcctccca cacgcagccg ccacattaag 3833161 ctttgtgttt ctgcgcttta caagccgtat cgcttactcc gtgatgctca ttagtttcgc 3833221 tgtcaccggg gtctgtttgc tatatgttcc ttttttagct gcattgttca cggtttgcat 3833281 cacacacgcc tgtattgggc tggcgctcgg cttcgttttt cctctgctgc taagccatgt 3833341 cgtcgaaatc agttctgccc gtttaaaaat gtcagtgatg gggttttacc aatcatttta 3833401 tgcgctaggc atcttcctcg ggccccttct tgccggaaaa atcgcacagc ttatcgggct 3833461 tgcgggagtt ttttatggag ccggttctct ggcatttgcc gccttttttg tgatgctcgc 3833521 gcaaaaacgt aacatgatca attaatagct ttcataccgc cggaagcgcc acacagaaaa 3833581 cacggccaga agcatgatgc acagaatgga gaaagtgagt gaccatccga aaaaatctgc 3833641 ccgctctcca tgaagaagga tatgctccgc ctgcttgcaa atctcagccg gaagccactt 3833701 cgcaccatct ggaaatagtg aaacagcaaa ggaaacggct gctgtgagcc cgatcccgca 3833761 agccgcagct gctccgacag accggaatat cgtacttccg gcaaggccgg cggtcacaat 3833821 aaatatcacc caaagagcgt aaaggccaag gcttgcggca aagcggctga atgatgcgtc 3833881 ctcaaacagc agccggacgt aatagtaagc aagcccgtat ccagctgcaa acgacataat 3833941 gccgatcacg ctttggatga gccatttact cacgatataa tgggctgccg tcacaggccg 3834001 cgacataatc agcgctgtta ccccttgatt tctttcattg gctacactgc ccatcacgct 3834061 aaagatgacc agagccatgc caagcgtgtt gaattgagaa agcgtgctga ccatcacttc 3834121 agacccggag ggcatcgtaa aactgatttt catgccgtca ggaaggttcc ctccatgtgc 3834181 gatgatttcc ggcatataat aaatggtcag cggctgtgtc agcccgacga tcatcatcgc 3834241 aatcggcagc caaatcagct tgccgctttt ccatccttcc agccactcct tctgcaatag 3834301 cgccatcatc accttcatgc gtgcaccacc tttagataga cgtcttctag agactccgtt 3834361 ttctgttcaa agcgggtgac ggtcaatccc tttcggatac agtcacttaa taatgaccgg 3834421 ccagcgtgta tatcaggcag ctcgaaaacc gcttgggacg gattcttata gacaatagct 3834481 gagacgtaag gcttctcttc aagccaacct tccagcttct ctttcactga aagggtaaaa 3834541 acgttcgttt gctgctgttg tttcagctcc tgtaactcgc ctttccatga aatctcaccg 3834601 tttttcataa tcaccacttg atcacacacc tgttctgcat cgtgcaaaac atgtgtagaa 3834661 aacagaacgg ccatatgctt tttcagctcc cgcatcatgt ccagcacctc gaaccgtcct 3834721 gtcggatcaa gcgcagacac cggttcatcc aatatcaaaa acttcggttt atggagcagt 3834781 gcctgtgcca gaccgagtct ttgtttcatg cctcctgaat agcccccgat ccttttgtgc 3834841 gccgcttcgt gcaaaccgac aaattccagc atctcgccga ttttctcttg gcattttctc 3834901 ttcgaaaggc cggacagtct ccccgcaaat gtcaaaaatt catttgcggt catccacgaa 3834961 taaaaagcag gatactgcgg gaggtaccca atcaaacgcc gatccagctt tttctctcct 3835021 aacagcttta tggttccaga ggttggcgaa agcagtccgg ccagcatttg cagagtcgtg 3835081 gttttgccgg ctccattagg tcctaatagt gcgacacact cattttcatt cacgtgaaaa 3835141 ctgacattct ttacagcttc atggtgcctg tacgatttgc ataatgattc aatagacagc 3835201 atatcggctt acctttgctt tctgccgacg gtgaaaaata aaatcggccc gataatattg 3835261 atacatacga tgattgcagc ccacatccac tttggcccgt tcgtccgctc ttcttttata 3835321 cagctgataa gggcaaacac cgccaaagcc agctgtaata caatcagcgg caaaatcatt 3835381 tcccaagaaa tattcattgc ttgatccccc ttttcttccg atccggccta atgacaaaaa 3835441 agtaataaca aatcagaggc atcggtgctt gaatcaatcc gacaatcccc caaacccatg 3835501 ccatgtgatt acgttttttc gcatcaataa ataaaaagat tccctgcgcc aatacgatga 3835561 gacaagccgc aaccgttatg ataatttctg tttgtgtcat ccgcgtttca cctcgcattc 3835621 gccgagatgc ctttttttct cagccgcaat caaaatcggc agcaccgcaa gcacacaaac 3835681 ctgaagcaca ataaacacag caggagcttg agtgaaagct aagattgcag cactcacaac 3835741 catcagcgcg cagaatacaa ataaaatgat ctcttgaaga agtttttttc tgtattcagc 3835801 tttcatttgt gacagctggt gaagcagttc tttttgattc ggtatagagg gattggctgt 3835861 ttgatcaatt tttttccatt ctgactttaa atgatcagaa agcttttctt tattcatcat 3835921 cccactcctt tctgatttgc tggagccctt tatgaactct ggactttaca gtgccttctt 3835981 tgatttgaag catcaccccg atttcagcgt aggtatagcc gtagtaatgc cttaataaaa 3836041 ccggtgtgcg cagtttaggg tccagctttg aaaacagatc gagcgtttcg ctccactctg 3836101 cccctttcgc cgacacgtcc cacttgatct tgcggattgt ttcctccgta actgtctgat 3836161 tccgtttcca ttctctcttt ctctttttct ggtgatcgag atagagccgc gatgcaatgg 3836221 agatcagcca tgtggagaat tttgaacggc cctgaaagct tcttaaatgg atgtaccctt 3836281 tcagaaaggt ttcctgaaca agttcctcgc tgagatcggg gtgaagggaa agctttaaca 3836341 agtatttata taagaaagaa tagtgatagt ggaaaagggc tgtaaacgcc tcgtcgtttc 3836401 cctctttcgc ctgctggatc agccgctgtt cttcttgtgt atccaatgac cgtgatcccc 3836461 ccttttttgt ttttctgcct tatgagacga caccggattc aaaagcgttc atctttttta 3836521 caattctttt cagccattga cagatcaggc ttcccggccg tttggctgca tatccttatt 3836581 tgtaaacccc cttatagtct gttaagctat gactttatgt cgatttcaaa aaaacatcca 3836641 atatggagga cgatgcattg aaagtagaaa ggcgaacgat tgaatatatt ccgaatgaag 3836701 aaagacatgg taaagcgaaa gatttatttc ccgtatggtt cggggctaat atgcatatca 3836761 ccacgttagt gaccggcacg attcccgttg caatgggact taatctgttt tggagtgttg 3836821 ccgctattat ttgcggaacc ttaatcggtg ccatatttat ggcttctcat tccgcgcaag 3836881 gccctcagct aggcatcccg caaatgattc aaagccgtgc ccaattcggc gtaatcggag 3836941 cgattcttcc cctcttctta gtcatgttta tctaccttgg tttcttcgca agcagcacga 3837001 ttctggcggc cggaacctta agcagctttg ttcccatccc gggatcatgg agcattatag 3837061 gcttaagtgc cgtatgtttt ttactcacca ttttcggcca tgatttgatt cacaaaatgc 3837121 aaaaaatcct ttcttggacc tcttttgctg tattttttgc tgcaacgatt ctcatttttc 3837181 aattgccgat tccggcaggc agctggatac ccggagcgat tgatctgcca attttcctag 3837241 tggcagtcag cgcagttgcg acgtggcagc ttgcctacgc gccgtatgtt gccgattatt 3837301 caagatatct gccagttaaa acaccggctt caaaaacatt ttggtacagc tatgcaggta 3837361 catctgtcag ctccatctgg atgatgctgc tcggcgcatt gctgacaacc tcacttcctg 3837421 actttacggc aaactcaggc agccagattg tccaattgtt cggtcccttc tcgtttatta 3837481 tgctgatcat tgtgctattt gggcaaatgg caatcaatgt ttttaacctg tatggggctt 3837541 tcatgtccac gacaacaacg ctggagccgt ttctgaaatt aaaagtcacg cccaaagtca 3837601 gaatcatcat gatcctgggt gtcacgcttg tcggcacagt cttaagccta ctgggacaga 3837661 gcaattttat ggaactgttt ttgaatttta tctttttcat cagttatttc ttaattccgt 3837721 ggacggcaat caatttagtc gattactact tcgtccgcca cggaaagtat caagtcaaag 3837781 ccatgttcga cgtaaacggg ccttatggaa aggtcaattg gatcaccaca attgcgttcg 3837841 ttctgtctat cttgctggaa attccgttta tcaacacaag cttttacatc ggaccgcttg 3837901 ccaaaatgtt tggcggcgga gacatcgcat ggattatcgg cttggccgtg ccttctgtgc 3837961 tttactatgt attaatgaaa ccgcgtctga aaaaacgggc ggggtatcaa gaaaagctgt 3838021 cttctctctg aagacagctt ttttatcatt caaatcgttt ccacacgcgg ggcaggatgt 3838081 cagatagctc atgagcgagc aacgtatgag cggagtgctc gtccgtccag agctcggcgc 3838141 acgcaccatg caaatagacc gcgtttaata cggcgtgctt tggatcttca tggcagcaga 3838201 gcatccccaa tatcatgccc gtcagcgtgt caccggttcc gcccttggcg agcgccccgt 3838261 ttccggttgg attgagccag cagtctccat caggaaacgc gatgacggtt tggtttcctt 3838321 ttaacacaat gacagtctgc agctgagccg cccattcctt tgcatattcc gctctttttt 3838381 tctgcaattc gttcacgggc acccctgtca ttcggaaaaa ctcgcccggg tgcggcgtga 3838441 ggatgacggg gccctcccgt ttcggatatg tgcgcttcgc cagcgctccg gcatccaaaa 3838501 taacaggaca atcagccgta agcacatgat cgactgcctg ctgtacgctt tccgtttgcg 3838561 gaaggcccgg tccgatggca atggcccggt acgtctcttc aagctgagca tccgccgcct 3838621 ttttccagcc gtcacgccaa taggtcgcct cgggcaaaac aggaacaatt agcgggatta 3838681 cgttttctga tgtaccgatg acaagcttgc cgagaccgct ccgcatggcc ccaagccctg 3838741 caagcagcgc tgctcccggc atgtcgtcac ttccagccag cagcaaagcc gtaccgtacg 3838801 tgcctttatg gctctccgca tctctttcag gaagcgtggc ccttacatgc tcttccgtcc 3838861 aaaatggaac attcatctct atccctcctc tgctttcttt tcctattttt cctgtccctt 3838921 ttctttttca aacaaaaaag acagcctttt agggctgtct tttattttac aggaacatca 3838981 aggtgataca ggcggcgata tcgttcgttt gccgccagca gctcctcatg ggttccttcc 3839041 atttctgttt tgccgttttc gagaaatacg attttatcgg ctgcttccac tcccgcgaga 3839101 tggtgtgtaa tccataaaat cgtttttcct ttcagcacct caaacaccgt ttccatcaat 3839161 tcacgttcgg taataggatc gaggccgact gttggctcat cgaggatgat gatcggtgta 3839221 tcctgcagca aaatcctcgc aagtgcgatc cgctggcgct ctccaccgga aaaacggatg 3839281 ccggtttctt gtacagaggt atgatatccg tcaggcaatg actcaatgta gtcatgcagc 3839341 ttgacctgct ttgcggcgcg gcgcacatcc tcgtcgcttg cttctccgtt tccgagcctg 3839401 atgttgttca aaatgcttgt atcaaacagg tgcggttttt gatttaacac ggccaccgca 3839461 tccgcaatct gatcctttaa cagcgctgtc tccactccgt ttaacgtcac agaaccggag 3839521 tccggtttca aggcgccttc gattaatgca agcgatgttg atttcccaga gccgcttcgg 3839581 ccgagcagcg ccattttttc tccttggcgc agcgtaaagg aaaagttgtg cagcacttgg 3839641 ctgctgttgt cataagaaaa cgtcacatca cgaaaggcca aggtgacatc ttgaagatcg 3839701 agaatttgat cccctgattc agtttgtgac gcctccggct gaggagccac attgttcatg 3839761 cgtctgatag aatcctgata gcccggcact tcgcctaagg catccgaaag cggcaaaaag 3839821 gcttccgtca acggaaacac cactagcaca aaagcggcaa tcatcgtttt agcgagctcg 3839881 ccgtccgctt gctgtcccgc tgtccaaaac agcatcagca aaataaggcc agcgacaagg 3839941 cattgcgcag caaagtcccg ccatcttgta aagcgttgtt ttttccgttc aagctcaaac 3840001 caatcacgtt cctctttttc ataagcatca ataaaagcat gccggcgtcc gctgaacatc 3840061 cagtcgctga cacccatcac agcatctgtc agacggctgt acagcacatt ccgtccgctt 3840121 ttcagcttcg cattcttcgc tctcgtcacg agcaaagaca caaccggaaa caatacaaca 3840181 agaacaaaca aatacagcgc aagcaatatg gcaaacggcc aagagaagaa gccgagcgct 3840241 atcactgaca cagcatacag gagcaaggct gagatcgcag gaaaaatcgt ttttaagaaa 3840301 gcatcctgca aatgctcaat atcctcagac aaaatgccga gcatatcccc cgtgcgaaaa 3840361 cgggaacgca gcatcaaagc acccggctca agcatattgt aaaggcggac gcgcatgtca 3840421 gatacgattt tcaaaatgat gtgatggccg acgagccgtt ccacatatcg cgacacagag 3840481 cgcgcaatcc caaaggtgcg cacagcgaca atcggcacat aaatgagcag aatgttttcc 3840541 ggccttgtcg ccgctttaga aatcaaaaaa cctgaggtga acatgagaaa agcagcagaa 3840601 aaaatcgtca ccgcacccaa aaagataacc agaacgaaca ggcgggcatt ttgcttgata 3840661 tacggcaaaa tccattcttc tttcttcatg ctctttcccc cagttgtgcc ttcacgagtt 3840721 tggtatacac accgtttttc tccagcagtt cattgtgagt cccaatttcc gcaaccctgc 3840781 ccccgtcaag cacgataatt tcgtccatat cgagcatcca gtgaaggcgg tgagtcgcga 3840841 gaaagacgag cttatcctca aataaatcca gcatcgtttc ttttatttca tattctgttt 3840901 cgatatcaag atgggcggtc ggctcatcca gcagcaggat cggacggttt cccaaaaagg 3840961 cgcgggccag cgcgacacgc tgtgcctggc cgccgctgag cgcccggccg ccttccccga 3841021 tccgcccctc taatccgtca ggaaggttgt tcaccagctc cgtcagtccc gctgaggcag 3841081 cagcacgtgt tgtatcctct gccgaagcgc ttggatggta gaagcgaatg ttgttgccaa 3841141 gcgtatcatc aaaaatgtac ggatgctggg gaatgtaaag aaggttcttc tgccagctgc 3841201 cgtcctgcaa atgggaccgg cttgtaccat taacctcaat catcccgcca tccggctcta 3841261 aaaatccgcc gagaatatca attaatgttg attttccggc gccgcttgca ccgataatgc 3841321 cgattttttt cttgcctttg aatgagagat gaatatcaga caccgaacgg ccgactgaca 3841381 cgcctgacag cttcagctca tcctgatcgg accaagcttc gagctgaagc ggcgtctctt 3841441 ctttaaaacc aggctgcgac aaaatctctt gaatggtttt tcctgcttcc tggccgttca 3841501 gcgttgcatg ataatcattc cccacttccc gcaccggcaa aaaatactca ggcgccagaa 3841561 taagcgccgt taaagcaggg ccaagcaaaa tatcgccgtc aatgaggcgc aggcccagaa 3841621 atactgcgac tgtcgccacc gacagcatcg tgaaaaaatc gagggcgaat gatgacaaaa 3841681 acgccacccg gagtgtgctc atcgttgcct tgcgataccg ctcactcaca tagaaaatat 3841741 ttttgctgtg tgacttgctc aaacctagga aacgcaatgt ctccagcccg cgaagagaat 3841801 caacaaaatg attggaaagt ctctgatagg atttccactg acgatccgct tttctctgcg 3841861 cgacaaggcc gaggagaatc ataaagatga tcagaatcgg catagcagcg actaaaatga 3841921 tggctgatgt ccgatcctga aaaaacacat aaatgacaac tgccgcaggc acaatcgcca 3841981 tgctgaccat tttcggcaga aacagctcca ggtagcggcg gaactggctg atgccttcca 3842041 tcgccagcgt caccatttgc cccgtcccct ctttctttgc aaagcggggg cctaatcgga 3842101 acagctgatc aagaaaactt ttcctcaaat ctgctcctgt ccgggcggcg tattgataga 3842161 cgattttctg tcgcgccacc gtcatcccgt gccgggcgat aaaagcgatg aggaaaaagc 3842221 cgatcaccgg taaaagggag gtaatgccct tcccgttgaa cagtccggtt acggcctcac 3842281 tcagccactc tgcctgcata ataatggcgg ctgtctgaat caacgttaaa caagtaatca 3842341 aggtgagaat ccgcttcatt cctttatatc gaaacaggtc ttttcccatt aataagtcat 3842401 aggctcctta tggctgacgc gcttccggaa gacataatag ctccagatct ggctgccgat 3842461 gacgaacggc aatagcgtta atgctgcaat tgacatgact ttaagcgaat aatctccaga 3842521 agaagcgtta gctactgtta aatcgtatgc gctatgaagc gagctgacca ttacacgagg 3842581 gaatagggaa ataaagatca ttcccacggt cagcgccaga ccagcgcctg tcatcccaaa 3842641 tgtccagccg tcttttttct tacgaataaa tacagccgcg agcataaagc agatgacaat 3842701 caaaacagcg agcggaatgg taatctcgcc gcggcgtgta aacatgtctg tctgatacgc 3842761 agaaagggcc gcgaaggcaa gaaccgctac aaaaacaaca cccattatct tttgcgccat 3842821 tttccgggcg cggttttgca aatcaccaat cgtacgcagc gtgataaaca ttaatccatg 3842881 ctggaagcaa agaagcgtta ccgtcacacc gccaagtata gaatatacat tgatataatc 3842941 agatacatgt gcgtgaatgt tcatgtcggc atcaatcggc atcccgcgga ataatgtcgt 3843001 gaacagcaca ccaagcacaa acggaggaat tagactgccg aaaaaaacga cccagtccca 3843061 aacctttacc cattttaaat gatccacctt gccgcggaac tcaaacgcga ccccgcggcc 3843121 cattaacgca agcagcacta tgacaaacgg aatgtaataa ccgctcagca tcgttgcata 3843181 ccagtttggg aatgccgcga aaatggcgcc tgcgccagtc aaaagccaca cttcattcgc 3843241 gtcccagaac ggcccgatcg tgttgatcag cactctgcgt tctaattcat tatggccaag 3843301 aaaacgggtc gccatgccga ccccgaaatc aaagccttcc aaaaagaaga atcctacaaa 3843361 caatacagca acgagtataa accaaagatc atgaagagat gccatggtat acctcctgac 3843421 taaatggatc tgttgataca ggcacatcat gatgattatc atgctccgca ccttttttaa 3843481 tctcacggat aaacaagaag acaagcagtg caccaagaat catgtacatc acaccgaatg 3843541 cgatgattga gaataacaag gaacccgctg ttacgttagg cgacacagat tgagcggttg 3843601 tcattaaccc cataaccgtc caaggctgac gtccgatttc tgtcataatc cagcccgcgg 3843661 agtttgcaag aaacgggaag gaaatcaacg cgatcatgat gcgcaaatac catttgctgt 3843721 tttcaagctt tttacggcgg tttaaccaaa ggccgcctaa cgcagcaaga atcatgacaa 3843781 cacctgctcc taccatgatg cggaagctcc agaatgtcgt tttcactggc ggaatgtagt 3843841 cgccttttcc gtatattttt tcgtactcag cctgaagggt tttcatccct ttgacacttc 3843901 cgctgaattt ctgataagcc aagtagctca aggcataagg aactttgatt tcatttgagc 3843961 ttttttcatt ttttgtatcg atcgtcgcaa aagcggtcca agcagcaggg tcaccgctgt 3844021 cttcccatag gccttcactg gcagccattt tcatcggctg tgattccatc aagtgctcag 3844081 cctgcatgtg tccgctaagg ccgacgccaa gaccggcaca aagaccgacg atcattgcga 3844141 gtttaaaaga ttgcttaaag aacggcactt cttttttctt cagcagttta aaagcactca 3844201 ctccggcaat aaagaaagct ccagtggcaa gcgcaccgaa aataacgtgc gggaattcaa 3844261 cccaaagctg agggtttgta atcaacgcgc caaaatcatt catttccgcg cggccgtttt 3844321 tgatcgtaaa gccgaccggc tcctgcataa aggagtttgc tgttaaaatc cagaaagatg 3844381 acatgatcgt tccgaatgat acgagccata tgcagagcgc gtgaattttc ttcggcaggc 3844441 ggtcccagcc aaaaatccat aatccgataa aaatagattc catgaaaaac gccaataatg 3844501 cttcaatcgc aagcggagcg ccaaatacat ctccgacaaa acgggagtaa tctgaccagt 3844561 tcagtccaaa ctggaattct tgcaaaatcc ccgttacaac accgactgcg aaatttatta 3844621 agaataagtg tccccaaaac tttgccattt tgagatacag ctcatttttc tttacaagat 3844681 aaagagtctc catcaacgca accataaaca caagcccgat agacatcggc acaaacaaga 3844741 agtgaaacaa cgttgttgat gcaaattgta tgcgggctaa taccaattca ctcatgcttt 3844801 ctcctccatt tccggttaaa actgttaatt tgctcactac ttcacaaata gaaccgagac 3844861 tttgatcagt aattcacaaa atagacgaaa aaaatattgc tcaatatttc acaaatgtgt 3844921 caaaaagtca tccaatatga tgcaagattg ccagactgac caaatgacac aatctctgac 3844981 tggttcatat taagtacttt acaacgattc atttcaaaaa taaagcctaa aatacctaaa 3845041 aagtcccgca ctatgtgacg gatttttgtc tattttgttg cttatttatg tcggctgcta 3845101 ggataaatga ccctttatta tcgtacatca acacatcgtt ccttgcgaac aaaatgcttg 3845161 cccccgcccc agcactcgag tctcagcatt ccgtcttaaa ccgattttag tcagaatgcc 3845221 tcttttcatt tgaaccggta agaggagaaa agttgaatag taaattttta atatattaat 3845281 aatttcaatt ttttagtata cttaacatag tgaacaattt cactgcatca agaatagggg 3845341 aggtttttca atgggagagc ttcaaacaca catgcaattg caaacggata caattcacga 3845401 aggggttcga aaagagaatt ggtttgcgaa agccatgaat ataaaagtag gcatcatacc 3845461 gcttcctgtg tatgccttgc tgtttatatt aatcactgtt tttgttatgc atcacgatgt 3845521 aaaaagtgac attttgacat ccattgccgt catggcgttt ttcgggttta cctttgccca 3845581 aatcggcaaa tcgataccga ttgttcgttc tatcggcggc ccggccatcc tagctacttt 3845641 tattccgtcc gctgtcgtgt actatcacct gctgcctaat gatatcgtca aatccaccac 3845701 agaatttaca gaaaactcaa actttctata tttgtttatc gccggtattg tcgtcggaag 3845761 cattctcggc atgaaaagag aaacactcgt aaaagcattc atgaaaatct ttattccgct 3845821 tattgtcggt tctgtcacag ccgctattgt cggactggct gtcgggacat tgctcggact 3845881 cggatttcag cataccctgc tgtacattgt cattccgatc atggctggag gagtcggaga 3845941 aggcgctatc ccgctgtcca tcggatattc tgacatcatg cccatttctc aaggggaagc 3846001 gtttgcactt gttctgccat cgattatgct gggcagcttg tgcgcgatta ttctagcggg 3846061 attgctgaac cgaatcggaa agaaaaaacc ggaatggaca ggcaacggca aagtggaccg 3846121 ctccgaagaa gagtcccctg cgctggagga atctcaaagc ggacagcaaa tgttcaacct 3846181 ttctttattt gcgtcaggcg gtatccttgc tgtttcttta tacttagtcg gcatgctcgc 3846241 tcacgatttt ttcggttttc cggcacccgt tgccatgctg ttactggctg ttctaatcaa 3846301 gctgttcaga ttggtgcctg cctcaattga aaatggcgcg tttggagtgt cccgcttctt 3846361 ttcaacagct gtgacctacc cgcttctctt tgcgattggg gtatccatga cgccgtggga 3846421 caagcttgtc gccgctttta acctcagcaa tattatcacg attctgtctg tcgttgtgac 3846481 catgatggcc gttggcttct tcactggaaa atggctgaac atgtatccga ttgaaaccgc 3846541 cattattaat gcatgccatt ctgggcaagg cggcacgggt gacgttgcca ttttaagcgc 3846601 cgctgaaagg cttgagctaa tgcctttcgc ccaggtgtct acccgcatcg ggggcgcgat 3846661 tacagtatcc ttaaccttat tgctgctgca ccagttttat tgatccccgc aagcaagttc 3846721 ttcgtcaaac gaaagagctt gcttttttgc atgtccatgt ttttgcaagt tcccatccca 3846781 tgctatagta atagttggaa atactagata gaaaggaatc tggcatgcct atgggaactc 3846841 atctatttct ctttatgctt ctcgggctgg gattttattt gatatcagcc ctagctgcaa 3846901 aactcattcc ggccatagac ttctggattg atattgttct atgggtcggc gctgcggctt 3846961 acatcttctc tcatctctca ttcatggacg gcattgtctc actcgcgaca atgttctact 3847021 gctattggac cgcaatggat ctcattgttt cagagcgtgt ggaaaaacct tcgggagact 3847081 ggcaggaaat cgagcttgcc aaaaacaaaa cacgcctcct gtcagacatt acgctgaccg 3847141 ccattgtgtt tgcaggggct gtcatttttt tcatctatgg acctgacaca agccctctca 3847201 aatatgtgat ccttctcgga atgatctccg gcggaggggc acttgtgaag cgaatactga 3847261 atgtttttag cgtaaaggtt ttttattcag cagccttaga aaaattgcat atcagctcac 3847321 actatgaaac ccgtacatac ccgctttccg atttgaagaa cattcagctt gaatcaacag 3847381 cagatctctt aaagctccat ccgcttctga cgatgtattc atcccgttta gatttgacaa 3847441 caagctttca gcaagtcatt aaactgtctc ttcccggcga aacactgttt ctgacggtga 3847501 aggaaccgca aaaatggaaa acaattcttc aggaatacac agatgcagaa aacaatgtgg 3847561 acaatgtgat ttctgttttg ccgttttatc atcgaaaaaa tgtgaagcgg ctgctcggta 3847621 agctttattt tgccgccagc gtaaaagggg tatccgctta cgccttattg gtgctcgcgt 3847681 tatacgcatt acacgcctct ccatgggtca tggctgttgc cgtaatccta tattgggtat 3847741 tcaacatgta tatgtcagac cgtgtgttgc gggcggcgat ggacgccaag tcttgtcatc 3847801 atccgcatgt acaggccgcg gccgataaga ttttcagatc ggccggcatt tcccatgtcc 3847861 gcatatacga aacggagagt gatgattaca acggaatggc agtaggcatg aatgtcggga 3847921 ggtcaatggt catcctgaca agcgccacac taacacttcc acagcgtgtc attgaaggca 3847981 ttctggccca tgaggcgatt catatcaaaa aacgtgacgt tctgtcatca cagcttttgc 3848041 gttttctata tcttggagct gtcgtgggga ttttcctctt gtttgagcag catatcaccc 3848101 atcccgaggc ccacaaaatt gcgctttggg ctttcattat ggcaatcatt atcctattcc 3848161 agctctatca atccttttgt tcacaatgga tggaggtgcg tgctgacaac cttggcgcat 3848221 cattgctgga cggcggttac aaacaaatgg ctgaagcctt gagaatcttg gcggttcggc 3848281 aagatgagga tatacagaaa caaagtgcct atagctctga agcaggtgaa gacgagcttc 3848341 aaattgattc tctcacccgt gataaaagct ggtttttcag attgattgat tttcagttcg 3848401 ctcctcatcc tcctatgtat tggcgtgtcg gcactttatt gtcaaacaaa ggacatgggg 3848461 tgctaaagcg ctggctcaga gaccgactga aagaatcgat cactttgaaa tgaaaccggt 3848521 cagcgtttca tccgtataac agatatggtg aaaaaaggga gtgacgcgaa gtgattgtga 3848581 tcatcttatt gtttatatct attattgttt ttctttcagt cattcagccg cagccctcga 3848641 aaaacaaaag ccgccagcag gcggacagcg ggtatttcgg ttattcagat catagctcac 3848701 accatgatgg atgcagcagt gacggaggtt tcagcgattc cggctgtggc ggcggagggg 3848761 gcggcgatta aacgccgcct ttttttattt cattgattcg atgtacgcac caaaagccga 3848821 gcctgacatg cctggggaca cgcgcacacg atggagggca tacattccct ggtctctcga 3848881 agccgcgccc ggttctgtcg tcacgcccat ttgatagcct gttttttcag cggccttcag 3848941 cgtctcctca ttgtagcgcc ctaccggata gctgatgatg gtggtttgct gatgaaacat 3849001 gttgtcgaac agctttttcg aatcagccat ctcactttgc tgctgttgag gcgttaatcc 3849061 gttcagctca aggtggtcaa tcgtatggct ttcaatcgat atgccgtgct gtgccatttc 3849121 cttcatttgt tcctctgtca gatggtgctt atgtccgatc gatttgccga tcataaaaat 3849181 cgttgccttc atcccgtact ttttcagcac cggatacgca tcttgataat tgtcggtgta 3849241 cccgtcatca aatgtgatca gcacgcactt ctcactcggt tttttatcct gcgtcagcat 3849301 gagagatgcc tctttcggcg ttaatgtctg atagccgtta tcatgaagcc acttcatatg 3849361 cgcctcgaat tctttctttg gcacacggag gctgtttcct gaagaaatgc tgtggtacat 3849421 caaaatcggc agctttgccg gtttctctgt tttgatccat gcggatgtat cgtcttcttt 3849481 tttctgaact tgtactgcct ttttttccgg tttcttttgt tccgcttttg gcatcggctg 3849541 ctctgcattc gcctcttgat cagcacaagc cgcaagagcc aaacagctgc ccaaaagaaa 3849601 gatgcttaaa aacaatcgtt tcatcgttct cctgctttct gtctatttct tcctcctttt 3849661 tcatcggttt gattctgaga ttttcaatag caaaaaaccg gacatgtctc catgtccggt 3849721 ttttttgatc ttatcggatt ctcacttctg tctcactgtc aaagaaatgg cctttattca 3849781 tatcaaatgc aaccgtcagc tcatcgcccg attgaatatc gaggcgggcg tcgatccgcg 3849841 caataaagtc ttggttgtct atctgcgaat aaatcataat ttcagaaccg agcagctctg 3849901 caacattaat tttcgcctta atcgaagagt tcttatatga ttccacgaca atcaattcat 3849961 catgtatatc ctcaggacgg atgccgaaga tgacctcttt gccgatgtag cctttttcac 3850021 gcagcacttt catttttcct tccgggacgg ttaatgccgc agaaccgatt ttgattaagc 3850081 catccgtgag ctttcctttg aaaaaattca tcgccggtga tccgataaac ccgccgacaa 3850141 agacgttttc agggaattca tatacatcct tcggcgtccc gatctgctga attttcccat 3850201 ctttcatgac tacaatccgt gtcgccattg tcagcgcttc tgtctggtca tgcgtcacat 3850261 aaatcgttgt agtctgcaat ctctggtgga gcttaatgat ttccgcccgc atttgcaccc 3850321 tcagcttcgc gtccaggttt gacaaaggct catccatcag gaacaccttt gcatcccgca 3850381 cgattgcccg gcccagcgca acccgctgtc tctgtccgcc tgacagcgct ttcggtttac 3850441 ggtgcaaata ttcctcaagc ccgagaattt tagcggcttc ttcgactctt tttttgattt 3850501 caggcttcgg cattttccga agcttgagcc cgaacgcgat attatcgtag accgtcatat 3850561 gcggataaag cgcgtagttc tgaaatacca tcgcgatatc cctgtccttt ggcgctacat 3850621 cattgacccg ttttccttca atataaaaat cacctttcga aatttcttca agtcctgcga 3850681 ccattcgcag cgtcgttgat ttcccgcagc cggacgggcc gacgaatacg ataaattcct 3850741 tatcggcaat atgaaggtta aagtcatcaa ccgccggttc cttctgatca taaaatttat 3850801 aaatgtgctc catccgcaat tcagccatct aacatccccc tttgttattg taaacgcttt 3850861 cttatattga gtgtaacagc aattccctct cgctaaaatg ggcagcgttc ataaaatcac 3850921 ccagccattt ttcgtgcata tttccaattt attctgaact ttcattttgc aggcagataa 3850981 aataggcaag aagcgcgcct ttgtacgatt tgatatctat ccctgaccgc tcaataaatt 3851041 tatcaatccg atattgcagg ctgttgcgat gcagatgcag ctttttcgct gttaatgtga 3851101 cgtttgagtt gttttcaata aacagcttaa tggtcttcct tagctcagat tcacttccaa 3851161 ataaaagctc agcttcttca gagagcagtg tttccagttt ttctttttct gtttctaata 3851221 atagaaaagg aaagatcatc tcaaaggtca cactctgcac ctgaggcagc cgtttttcag 3851281 caaacaggaa atacgcctgt tcacgagcgt aatgttttcg cagacactca tccggctcgt 3851341 aaaatcttcc ggcgtaaaaa cggacactga agtagaaatc actttcaaga accttagcga 3851401 gcgattccag ttcgtccttc tccgccgccg cttcactttc ctgctcgaca atcacacctc 3851461 tgtcctcatg gatccacaca atcacaaaag acaccggcca aaaatggcga accgcttccg 3851521 taaaggacgt cctttctatt ttgccgaata aatgaaagtg aacaaatctc gtccgtttct 3851581 ttatatacgc cggcaattcc cctctggaaa aaaggaacga aaaccacttg ttttcctcag 3851641 gtgatttcat agacagttga ttgccctcat ccgcaggcgt caaaaatgac tgcagcacca 3851701 atacttcttt ttcactgatc tctgttttcg gaatggagat atatctctga ttgctctcat 3851761 caaaaaaaca tagacagcct tcccttatgc aaagctcctc agacacaatc gaaccgggat 3851821 aaatagccag cagcgatttc atagagtctc ctctcttatg taaggatctg tatattcagt 3851881 ataaggcgaa acacacatgt tctccactaa aaaagagtat atccggtata gatagacgag 3851941 aaactgaaag ggaaacctca ttcgtttaca tattggcttc agcggaaata gaagaagaca 3852001 tgcaggacca aaggagggtc atcttatgag tttcgaaacg ttaaacaaaa gttttatcaa 3852061 cggaaaatgg actgggggag aaagcggacg tacggaggac attttgaatc cgtatgacca 3852121 gtctgtgatc acaacagcat ctttggcaac gggcaaacag cttgaggatg cgtttgacat 3852181 tgcacagaaa gcccaaaaag agtgggccaa gagcacgacg gaagaccgaa aagccgtgct 3852241 gcaaaaagcg cgcggctatt tacacgaaaa ccgtgatgac atcattatga tgatcgcccg 3852301 cgaaactggc ggaacgatca ttaaatcaac aatcgagctg gaacaaacga ttgcgatttt 3852361 agatgaagcc atgacgtata ctggtgaatt aggcggcgtc aaagaggtgc catccgacat 3852421 tgaagggaaa accaataaga tttaccgcct tccgctaggt gtcatttcat cgatttctcc 3852481 atttaatttc ccaatgaatc tatccatgag atccattgcg cccgcaattg cgctgggtaa 3852541 cagcgttgtt cacaagcctg atatccaaac tgctatttcc ggcgggacca tcattgcgaa 3852601 agcgtttgaa cacgccggtc ttcctgccgg tgtccttaac gtcatgctga cggatgtaaa 3852661 ggaaatcggg gacggcatgc tcaccaatcc aatcccgaga ttaatcagct ttacagggtc 3852721 aacagcagtc gggcgccaca tcggtgaaat cgccggtcgc gccttcaaac gaatggcact 3852781 tgagctcggc ggcaacaatc catttgccgt tctttcagat gcggatgtcg atcgtgctgt 3852841 ggatgccgcg attttcggaa aatttattca ccagggacaa atctgtatga ttatcaacag 3852901 gatcatcgtt catcaagatg tatacgatga gtttgtagaa aaattcaccg cccgtgtcaa 3852961 acagcttccg tacggcgatc aaaccgatcc gaaaaccgtt gtcggcccgc tgatcaacga 3853021 gcgccaaatc gagaaagcgc tggagatcat tgagcaggca aagacagacg gcattgagct 3853081 tgcggttgaa ggaaaacgcg tcggaaacgt gctgacgccg tacgtctttg tcggtgcgga 3853141 caacaacagc aaaattgccc aaacggagct gtttgcccca atcgcaacca ttattaaagc 3853201 tggcagcgac caggaagcga ttgacatggc aaatgatact gaatacggcc tcagctctgc 3853261 ggttttcact tctgatttag aaaaaggcga aaagttcgcc ctgcaaattg acagcggcat 3853321 gacccatgtc aacgaccagt ccgtcaatga ttcgccgaat attgcctttg gcggaaacaa 3853381 agcaagcggt gtcggccgtt tcggcaatcc gtgggtcgtc gaggaattta ccgtgacgaa 3853441 atggatttcg atacagaagc aataccgcaa atatccgttc taaatgaaaa aatccctctg 3853501 tttcaagtac agagggattt ttctttattt agatatatcc acaaaccctt cgccaaacac 3853561 atcgcgtacg tcatgtacga tcacaaacgc ttttttgtcg cagcttctaa tgattttttt 3853621 cagcatagac agctcctgtt tgttaatgac gatatacaaa atctcttttg actggcccgt 3853681 ataatttccc ttccctgata aaatcgtcac gccccgatcc atcaaggtat ttacctgctc 3853741 tgcaatctca ctcttatttt ctgaaatgac cgtaatggct tttttcgtat tcaaaccttc 3853801 aataatgaag tccatcactt tggtaccgat atacagcatc acgatcgtaa acatcatttt 3853861 ttctgcacca ataataaaat aagagctaaa tactacgatt aaatcaaaaa acaagagtgc 3853921 atagctgata ttccagtcta aatatttatt agcaattctg gccagaatcg cggaaccggc 3853981 cgtcgtcccg ccgacccgga taatcatgcc gatcccgact ccggcaaata cacctgcgaa 3854041 aatcgtatta atgatcaatt catcagacgg aatgctccac ccatgtgtca gatgaagaaa 3854101 aagcgaattt gccgcaaccg caatgatcgt ataaaccgtt gtttttccat caagaaactt 3854161 gtagccgatt aaaagcaaaa acgcatttaa gataaagttc gtgacaccag gagaccattg 3854221 aaacagataa tacaaaatca gcgtaatccc agtgactccg ccttccccaa gatcattggg 3854281 aatcgcaaat aaattaaccg caagcgcgaa gaaaaaagcg ccaatcacaa gcataagtac 3854341 atccagcatt ctctttttca tcacgaaaac actccttttc attgttctgt tctagcaaat 3854401 aaaaaaaccc aggagaacgc tctcgaaaaa gagcagaaac tcctgggctt ttatcccacc 3854461 gtgtcataac agccaagctg ctatgtgttt tctctcggtc acagtccaat ttgcattgcg 3854521 gaaccctaga aaaccactgt ttttatcata tccttttcac tttccaatat tagcattata 3854581 agggacggtt cgaattggtt caaggggtat ttgcggagtt ttcatcagat aagctggaaa 3854641 aaaatacgat ttatctatta aaaaagaaca gatataaccg ataagaaaaa aagcatatat 3854701 tttacaagcg aatgtaacta taaatgataa taattataag aaattcataa ttttatattg 3854761 actaagagaa ataatatagg cattatagta catatgtttc gtacatttta ttacatagga 3854821 ggaaatataa tggcaggaaa actagtaccc tgtaaagctt gcggtcaaga aattgcaaag 3854881 ggtgtaaaaa aatgtcctaa ctgcggtaag gatcaacgta acttttttat gcgacataaa 3854941 atcattacgt ttattctcgc agttgttgtc atcattatta tcggtaatat gattggcggc 3855001 ggaggcggct cagaagccac ttccaaaaca tcaagcagca gcaaagcaga aactgaaaaa 3855061 acatacaata tcggtgatac cgtaaaaact gaaaaaactg aagtgacggt tacgaaggta 3855121 gaggacagag atactgtcgg tactcaatat gttgaaaaga aagcatctga gggaggtaca 3855181 attgtagctg ttcaatatac aattaaaaac gtatctaaaa agccgattag ctctttttca 3855241 attccaactg ttaaattagt tgatgctgat ggtacttctt atgattctga tattgatgct 3855301 tctgtaaact atgcaactga gacaaaagtt gataactcta aaattttgag tgatctaaat 3855361 cctaatatta aagtaacagg tgtaaaagca tttgaagttg acaaggaagc ttatgcaaaa 3855421 ggcacttgga aactaaaatt cagtaatgat gttattgtga aaatcaaata acagctaaca 3855481 agggtgcctg tttaggcacc cttgttcttt aaaaaaggcc ttctcaattg agaaggcctc 3855541 cattcttatt ccgcactctt atacccattc acattagaag actgccatct ccaggaatca 3855601 gcacacattt cctcaaggcc gcgtttcgct tcccagccta gttctcgctt ggctttcgca 3855661 ggatctgcaa agcatgtggc gatgtctccc ggacggcggt ccgcaaaacg gtatggaacc 3855721 tctttccctg acactttttc aaaggctttg accatttcca gcacgctgta gcctgtgcct 3855781 gttccaaggt tgtatgcatc ggctcctgta gagttcaata ctttttccag cgccttgacg 3855841 tggccttctg cgagatcaac gacgtgaata taatcgcgta cgcctgtccc gtcttttgtc 3855901 ggatagtcat ttccgaatac gcttaattgc tcgagcttcc cgactgctac ctgtgccaca 3855961 tacggcataa ggttatttgg gattccgttc gggtcttcac cgatccgtcc gcttggatgc 3856021 gcgccgaacg ggttaaagta acgaagcagc gcaacgctcc actcattgtc ggctgtatgc 3856081 aaatcacgca atatttgttc aagcatgagc ttcgtctgcc cataaggatt tgtcgcgcct 3856141 aatggaaagt cttccgtaat cggcgatgtt tccggaacgc cgtatactgt cgcagatgaa 3856201 ctgaatacga ttttcttgac gccgtatttc tccatggcct cgcataaaat aaacgttcct 3856261 gtcaaattgt tatgataata tttgagggga atcgccacag attcgccgac tgcttttaac 3856321 cctgcaaaat gaatcacagc ttcgatttca ttttcagcaa aaacggaatc taccgcttcc 3856381 cggtccaata aatccgcttc gtagaacgtt aaatcttttc ctgtaatctc cttgacacgg 3856441 ttcagcgctt cagctgaact gttggacaga ttatcaagaa caacaatctc gtagccgctg 3856501 ttcaatagtt caacacatgt gtggctgcca atgtaaccgg caccgccagt aacaagtatt 3856561 gccatgatgt aaaccctcct aaaaaatgac ctgttttcat tatatagtgt ttagaaccgg 3856621 tccacatcca tttttaagaa gtttaatcgt ttattaatag ttttttcata ttttttagct 3856681 taaacccttg ccagcaattc gatagaggtt tcagcaagaa tgtgctcttt catttcttga 3856741 tagagctcat tcaagtaaaa gcccggctga agattcagct cagcatctaa agcatagacc 3856801 gtcaatgtat acgcatgatc cttgtcaggc ggtgtcggcc cgcaatactg gtgaatcacc 3856861 tttggatcgt tgcttcccgc aagcggtgaa gcaaagctgt tttgcccttg tatcatcaag 3856921 tcctgtcttt cctcactcgc atgttcagga agctctccga tgtaagccgg aatattagcc 3856981 gctgtccagt gaatccagct gaatccgcat acgggaatgg cgtcatgatc gatgaaagta 3857041 agtgcgagcg tctttgctcc ggacgggatg tcatcaaaat gaattggaaa ggatacaaat 3857101 gggtttcctt ctctcttata tttttcatcc gcgtattttg aatacttgtc atgtaaatat 3857161 ggatttgctt ctacgtatat gttcatatga atccctctct ctattttctc gttctatagg 3857221 tatactaaac gaatcgatgt ataatcagtg ataaacaaat acgcatgtaa acgtaacaat 3857281 ttgttatgga taacttgcag tgaaggagat atttcatgga tttaaaatgg ctgcaaacct 3857341 ttattgccgc agcggaatca gagagcttca gggaggcggc tgagcatctg tatctcacac 3857401 agcctgccgt ttctcagcat atgaggaaat tggaagatga actggacatg aggttgtttt 3857461 tgcatagcgg aagacgagtc gtactgactg acgaaggcag gctctttttg ccttatgcca 3857521 aagaaatgat ccatgtttac caagctggaa agcagaaagt cagtcaatgg aaacaggggt 3857581 acagccgatc actcacgctg gccgtacacc cctacattgc gtcctatatc ttgcctcgct 3857641 ttctgccagc ctatatccaa aaacatccgc atgtcgagct ttcaactcat gtggctggat 3857701 ctgacgctat taaacaagcg gtggaacaca atgaagctga tattggtttg tcgcggaaag 3857761 acccgaacac caacactctt tattatcagc atatatgcga aggtacgctt tgtctggcgg 3857821 ctcctttcca agaaagcaga ccggatgctg catccgtctt aacccgctat cggctgctaa 3857881 cgcatgatca tccgtcatat ggggatgcct ttttagataa catccgatca cattacccgt 3857941 atcttcaaat gatggctgtc gggcagacgg atacggctgt ccacatgatg aaagcgggaa 3858001 tgggggcatc tttcctccct acctacatta tcaaacagga agaagccgaa aaaaagctga 3858061 tggctgtcag cacgcctgca catctagaat tgcctgcgtc ccaaacgttt atgatgtgga 3858121 aaagaaacag cgaagacatt cagcattttc acgccatgtt acatgacttt atgcagcgcg 3858181 aacaagtata gagctgaaaa atcaatctgc cggttgacgt ttttctttcc tattttcgct 3858241 atgcttaatg cagaaaggat ttgatgacat ggcgatgagc ccttatattt ttattgtatt 3858301 gattcttatt attttatcga tgtatcgaga aagaacggta aagcccggga agttgctgat 3858361 cattccactg ttgctcttat ggggcgtatc tgcatcgttt cagccggcgt attttcattc 3858421 cgtattacat gtggcgatca gcggcatttt attactgatc gggctggcct gcgggtttgg 3858481 cattgggaag atggtaaatg tacggattca cccggaaacc ggaaaggtca cttcacgcgg 3858541 ctcacttggg agtgttatcc tcattctagt gatactttct ttgcgcatgg ccgcgagaac 3858601 atggctgcct gagagcaacg agatgtttat tgccattatt cattctatgt tcttcgttcc 3858661 cctcggcacc atcacagccc gcaacatcat gctttacaaa gcatacagac gactgaccgc 3858721 tggcaaagta tccattcaat aaccgaaaga aggaccagca tgaacggaca aactccggct 3858781 cggcactact acaagaagct tgtgccgagc cttattctca ttttgaattg catacaattt 3858841 ttatctcatc caactaaggc tgatcccatt ttgttagcat ttgtatttgc ggtatactta 3858901 gcattcattt ggatcattcc ctatgtggca tccactgctg ttagtttgag catattcatc 3858961 ggactctggc tcctgaccga tttcttttgg gctgtttccg gccaagagca gggtgccgcc 3859021 tattttttga ttgtattttt aatgatatat gccgccttta gactcccttc acggctatcc 3859081 ttgatcttca cagcatgttt aattggaggc aacatattac tcctatcctc acaaggggga 3859141 agcttgaata ccatcatcag caacatctcg atcatgctcg gtctgtacgt cctcttctcc 3859201 tccatgcgtt tcagacgaga agcgagaagg gaggctgaac ggaatcatgc tgaattggca 3859261 aaaatgcatg tgcagctgga gcatgctcat aaagaactcc agaaagcgca tgcagagctg 3859321 caggaggctt ctgttctttc attaaggtac gcggtccttg aggaacgtac aagaattgcc 3859381 cgcgacattc atgacagcat cggtcacgag ctgacttctg tgattgttca gcttcaatcc 3859441 cttccctata tccttaaaag cagcaaggag gattcagaaa aagtcattca aaatgtactg 3859501 agtgtcgcca gggagtgtct tcaagaagtg cggtctgttg ttcaccaaat gggccgtagt 3859561 gaatcgatgg tggggcttac cgctttgcgg gggctcattc atcaagtgga ggaacggagc 3859621 ggcttgcacg tttctttaga tactgccgga ctgtcagaag agtcttggcc tccaaacgtg 3859681 agcgaaacga tctaccgcat cttgcaggaa gcgctgacca atatcattcg tcacgctgac 3859741 gcttctcatg cggcggccgt catttctaat gacaagtccc atctctatgt cacaatcacc 3859801 gacgacggac aattcaccgg cagccttact tatggatttg gcctgacagg aatgaaagag 3859861 cgcgcagaaa aagcaggcgg ttcccttact ttcagtgccg tacagccgag cggcctgaaa 3859921 attgagctgt cattgccgct catgacaacg aataaggagc aaaaagatga acaaagataa 3859981 aatacgcgta gcgcttgccg atgatcagcc gcttgtgcgt gaaggcttcc gctacgtcat 3860041 caacgcacag acggatatga cggtttctgg cgaggccggc gacggtcacg atattatagc 3860101 actcgcaaaa caaacaaaac ccgatgtcat cctcatggat gtccagatgc cgcgttgctc 3860161 aggcatcgaa gcggcgaaag acattatgtc cgcacttcca aatacaaaga tagtcatttt 3860221 aaccaccttt gacacggaag aatacgtatt tgaaggcatc cgtgcgggcg cagtcggcta 3860281 tctgctgaag gatacacttc ctgaggagtt gatagatgcg attcgcgctg cggccagagg 3860341 cgaggcgatt ttccgtacag tcacagctgc taaaatcatc agtgagacat ttcgggcgaa 3860401 acagcaaact catgccgaag aactggcaga gccgttcacc aaaagagagc ttgaggttct 3860461 tcagcaaatg gcctacggac tgagaaatga ggatattgct gaaaagcttt tcgtcagtga 3860521 aagcactgtg aaaacccacg tgcaccgcat cctgcaaaaa tgcaatgccc aagaccggac 3860581 acaggcagtc gtttttgcca ttcgaaacgg tattgtgcaa tagaaatctc tcatcccgcc 3860641 atgctaaaat aagacaaagg agatgattgg aaatgaaaga agaaatcatt gaacggttta 3860701 ctacatatgt aaaagtcgat acacagtccg atgaatccgt tgacacttgt ccttccacac 3860761 ccggccaatt gacattagga aacatgctag ttgatgaatt gaagtccatc ggcatgcagg 3860821 atgcagccat tgatgaaaac ggctatgtca tggcaactct tccctccaat actgaaaaag 3860881 acgtgccgac aatcggcttt ctcgctcacg tcgacaccgc tacagacttt accggcaaaa 3860941 atgtgaatcc gcaaatcatc gaaagctatg atggaaaaga catcgttctt aacgaacagc 3861001 tgcaggtcac cctgtcacct gatcaattcc ctgagctgtc cggctataag ggccatacac 3861061 tcatcaccac agacggcacc acccttctcg gcgcagacaa taaggccggt atcgctgaaa 3861121 tcatgacagc catggattac ctcatcaaac accctgaaat caagcacggc acaatcagag 3861181 tcgcctttac gcctgatgaa gaaatcggaa gagggccgca caaatttgat gtgaaacggt 3861241 tcaatgcatc ctttgcctac acggttgacg gcgggccgct cggcgagctt gaatatgaaa 3861301 gcttcaatgc cgctgccgca aaaattacga ttaaaggcaa caacgtacat cccggaacag 3861361 ctaaaggaaa aatgatcaac tctgcgaaaa tcgcgatgaa gctgaacagc ctgctgccgg 3861421 cagacgaagc gcctgaatat acggaaggtt atgaaggctt ctaccacctg ctgtcgattc 3861481 aaggagacgt agaggaaaca aagctccact acattatcag agactttgac aaagagaatt 3861541 tccaaaacag aaaagaaaca atgaagcgtg ccgttgaaga acttcaaaac gaatacgggc 3861601 aagaccggat tctgctggat atgaacgacc aatactacaa catgagagag aaaattgaac 3861661 ctgtcatcga aatcgtcaac attgccaagc aagcgatgga aaacctcggc atcgaaccga 3861721 agatttcccc catccgcggc ggaaccgacg gatcacagct gtcctacatg gggcttccga 3861781 cgccaaacat ctttacaggc ggggaaaact tccacggcaa atttgaatac atctcagttg 3861841 acaacatggt caaagccgta aatgtcatcg ttgagattgc aaagcagttt gaagcgcaag 3861901 cataacgcca aaagccagtc caaaaaagga ctggcttttt tgtgtgaaaa tgaaacattt 3861961 taaacacgtc ctccgtaaaa caagtatcaa caaatgagga ggaaaaacaa tgacaaaaca 3862021 tgcaatcgct gccaagagtc tcttgaaaaa atggatcatt tccaggccgc ttaacatgaa 3862081 aaagaaatcc agcccatttc aaaaaatcag aaaaatgttc aaacgcttct tcaaataaaa 3862141 catcaaatcc cctaaataca atccgtattc acccgtaccg cccaaatgct ccgtaatttg 3862201 ggttttttgt gttcaattcc gcaaaatagg gtataaacca aacaagcaag aaaacagcac 3862261 ccaaaaacag gtaattcgaa ttacgtaaac ttaggttaaa agttatataa aggaatttat 3862321 tttatcgtcg atagtaacta tagaaccaat catcaacaag agcaaacagc gtaattcaag 3862381 actattttca ggtcatcagg taatactgtt ttagagggac agtttcttgt tatttattga 3862441 tttagaattt tttgaatact ttttggcatt ttatccgtac aatagagagt accaaaactt 3862501 tttttgggag gtatgtaata tgatcctatt tattatcatc gcattatgcg gctatcttct 3862561 tttttctttc agcaaggaca atcgccgcaa accgcaaaag acaagccctc tgccagcagc 3862621 cgcacctcat cacaacaacc taatcgacct tgacgccatc cgccaaaaac gccggatgca 3862681 tctttcctaa ttctatattt caaacgaaaa ggctgctgaa tcacgcagcc ttttaaaatt 3862741 gttttgattt agagcctgaa accttttcgc cacctatccg taatttcata caaggcaaac 3862801 ccaaaggaga cttcagcaat gatcgagtta tttatgaaac aaaaaatgtt ctcatttaaa 3862861 gatgcatttc acatttatga ccgggatgaa caagaaacat tcaaggtgga ggggcgtttt 3862921 ttctcgttag gagactcatt acaaatgaca gactcatctg ggaaaacgct cgtttccata 3862981 gaacaaaaac taatgtcttt attgccgcgc tatgagattt caattggcgg gaaaacagtt 3863041 tgtgaggtaa cgaagaaagt aacgttttcc aaaccgaaat ttgtgatttc cgggcttaac 3863101 tgggaaatag atggtgattt atggagggat gaattccaac tgacggacgg ggaaaatgtc 3863161 cggatgtcag tgagcaaaaa gtggctcagt tggggtgatt cctatcactt gcagattgca 3863221 tacgaggaag atgttctgat ttgcactgcc atcgctatcg tgcttgatat ggttttatat 3863281 aacgatgaag atgaaagtat tttctaaaaa gcattgacaa ttgatccaaa agtaataata 3863341 ttaagataat tgaaatctga atatgaagtt gtaccttatc aagagaggtg gagggactgg 3863401 ccctatgata cccggcaacc gctgtttcaa acagaatggt gctaaatcct taagaacatt 3863461 gcgttcttgc agatgaggcg gagatttgat cgttcaagct cttccttaca caaaggaaga 3863521 gctttttaca tgcttaatat ttcagaaaag aggcgaataa catggctcaa caaacgaatg 3863581 ttgcaggaca aaaaacagaa aaacaacgca aagcaccttt ccgcgccgat catgtcggca 3863641 gcttgcttcg ttccgttccg gtaaaggaag cccggcaaaa aaaagcggct ggtgagatga 3863701 cagcggaaca gcttcgtgat atcgaaaatc aagagatcac ccgcatcgtg gaaaaacaaa 3863761 aagaaatcgg tctcgatgtg gtaacagacg gggaattccg gcgttcctgg tggcattatg 3863821 acttcctgga agggcttgac ggtgtggaac cgttcatccc ggctgagggg attcagttcc 3863881 ataacacaaa aacgaaagcg cgcagcatca aagtgacggg aaaactcgat tttacgagcc 3863941 acccagcgct cggtgattat caatttttac atgagattgc cggtaacgcg acgccaaaat 3864001 tgaccattcc cagtccaaat atgctgtttt ttggcgaaaa ggcggataaa gggatttatg 3864061 acgatcaaga ggaatacttt catgatatgg cccaagcgta caaaaaagca atcaaagcct 3864121 tctatgatgc tggctgccgt tatctccagc ttgatgatac gtcatggtct ctcttctttg 3864181 aggacaaagg cagagaggtt gtccgggcgc tcggcggtga tccagaaaca ttgccagcca 3864241 tatttgccaa aacaattaac gatgccgtcg cagaccggcc tgacgattta acgatcacaa 3864301 tgcacatttg ccgcggcaac ttccgctcaa cctgggcggc atcaggaggg tacgacgctg 3864361 tagcggaaac gattttggac ggcttaaacc ttgacggcct tttcttggaa tacgatgatg 3864421 accgctccgg aaactttgat ccgctccgtt ttgtgaagcg caaggatctg caaattgtgc 3864481 tcggcttgat cacatcgaaa tacggcgagc ttgaaaatcc tgaggatgtg aaacgccgta 3864541 tcaatgaagc cgcgcgtttt gtcagcttgg accagctatg cctgagcccg cagtgcggtt 3864601 tcgcctctac agaagaaggc aaccttctga cagaggagca gcaatgggca aagctgcgcc 3864661 atgtcatcga cattgccaac gatgtgtgga gataatctat cattgacaga aatagaaaat 3864721 gtgtgaataa tagatactat cagaaaattt aataaaaagg ttttccttat caagagaggt 3864781 ggagggactg gccctgcgat acccggcaac cgctgtttaa cagaatggtg ctaaatcctt 3864841 tagagcaatg attgctcttg aagataaggt tgagattgtc acgcaagctc ttccttatcc 3864901 aaaggaagag cttttttata tttgaatgga aagaaggaat ggacaacatg tcacaacaaa 3864961 caacacccgc agaacaaaaa tcacttcaaa gaaaaaaacc gccgtttcgc gcggatcaag 3865021 tcggaagcct gctaagatct gagcccgtca aaaaagcgcg gctgcaaaaa gcggccggcg 3865081 aaatgaccgc tgagcagctt cgccaaattg aaaacgacga aatcatccgc attgtggaaa 3865141 aacagaagga aaccggcctg aacgtcgtga cagacggtga attccgcaga gcatggtggc 3865201 actttgattt cctggaaaac ttagatggcg ttgagccgtt tactcctgag caaggcattc 3865261 aattccataa cgtacagaca aaagcacgcg gcattaaagt cacaggcgat atcgactttt 3865321 caactcaccc aatgcttgaa gattactcat ttctccatag cattgccggt gacgcgacgc 3865381 caaagatgac gattccaagt ccgaatatgc tgtttttccg cggaaaactg gaaaaggatg 3865441 aatacaaaaa cgattatcaa cttttccagc acgatgtatc caaagcatat aaaaaagcga 3865501 ttcaagcgtt ttatgacaga ggctgccgct acctccagct tgatgataca gcgtgggccg 3865561 ttttcttatc agaaaaaggc ttaaaacaaa tcgaagcgtt cggaacaacg cctgacgagc 3865621 ttcgccagct gtttgcgaaa tccattaacg acgcgattgc agaccgcccg gatgacttga 3865681 cggtaaccat gcatatttgc cgcggcaact tccagtccac ttggacagcg gaaggcggct 3865741 atgacgcagc agccgaaacc atttttgacg gcttgaatct tgacggactt ttcttagagt 3865801 atgatgattc acgctcaggc ggatttgagc cgctccgtta cgtaaaacgg tctgatcttc 3865861 agcttgttct tggcttagtg acatctaaat tcggtgagct tgaaaatccg gatgacgtga 3865921 aacgccgtat cgaagaagcg tcccgttatg taagcttaga ccagctttgc ctcagccctc 3865981 aatgcggatt cgcttcaact gaggaaggca acaagctgac tgaagaacag caatgggcga 3866041 agctccgcca tgtggttgag atcgctaatg atgtttggaa ataagcaaag aaaaaaacac 3866101 acttgattcc ctagcggagc aagtgtgttt tttatgtcat tgtgcggtgt agcccccatc 3866161 aaggacgaca gcctgcccag tgacgccctt cgccttctcg cttgccaaaa acacggcata 3866221 atccgcaatt tccttgacgg aaagcagtcg cttttgcggc acaagcggaa aaatgacttg 3866281 ttcaagtaca gagtcgtaag ggacatttct agttttcgat agatcgctaa gctgattgcg 3866341 tacaagctgg gtatcgacat aacccggaca gagcgcattg actgttatgc cgtggggcgc 3866401 gccttccagc gcccctactt ttgtgagtcc aatgacgccg tgcttggcgc tattataagc 3866461 ggatttccct gcaaagccca ctaatccatt aacagacgca atattaatga ttctgccaaa 3866521 ctgctgtttt ttcatgatcg gaaaaacatg cttcattgca ataaagggag ccgtcagcat 3866581 gaccttgatc agctgttcaa aggtgtctgt cggaaactct tcaatcggag cgacgtgctg 3866641 aataccggca ttgttcacca gaatatccaa gcggccgtat tgtttttgga tgacgttcac 3866701 cgtatcagca acttgcgctt cctttgtcac atcatacgga atggccgccg cgtcaaagcc 3866761 ttcttctgca agcttggagg ctgctttttc acatgcttcc ggacggaggt ctgaaacgat 3866821 gacgctggca ccttcccggg cgaattctct tgcgatttcg aatccgattc cgccggcagc 3866881 ccctgtcacc aaagcgactt gttttctcat gtcaaacacc ttcccattaa gaattgagta 3866941 cagactggct tacagcgaaa tcagcttctg ttttttcata aacctcttca attgtgacac 3867001 catcctgaag ctccgtcagt gtcatgcggc cgttcacaaa atcaaataca gccaaatccg 3867061 taatcagcct gtgtacgact ttctggcctg tcagcggaag ggagcatgtt tttttcacct 3867121 ttgattcacc atgcttattg acgtgctcca tgatgacaac gattcgtttc gccccgttga 3867181 cgagatccat ggcgccgccc atccctttta ccattttgcc cgggatcatc caattggcca 3867241 aatccccctg ctccgaaacc tccattccgc cgagaatagc taaatcgata tgcccgcctc 3867301 ttatcatcgc gaatgactca gcgctgtcaa aataagaggc gcctgtcact tcagtgatcg 3867361 tttcctttcc cgcattgatc aaatccgcgt cttccgttcc ttccagagga taggggccaa 3867421 ttccgagcaa gccgttttcc gactgaagca tgacgtgaac gccatcgggt atctcatttg 3867481 cgacaagcgt cggcattcca atcccgagat tcacattcat gccgtccttg atttcttgta 3867541 cagcccgttt gaccattcgt tttctcgctt ccttcacttg gcctcaccct ttcccgatgc 3867601 ttgctgaact gttcgttttt caatccgttt ttcttggctc gcgccaagca cgacatgctg 3867661 tacgtaaatt cccggcgtat ggatgtgatc tggatcgagc tctcctgctt ccacgatttc 3867721 ttccgcctcg gcaatcgtga tcttgcctgc catggcggca atgggattga aatttctcgc 3867781 cgttttccta aaaatcaaat tgcccatggt gtccgctttc cacgctttga cgatcgccac 3867841 atcgccggta atgcctcgct ccagcacata agtccggccg ccgaatgttt tatgttcttt 3867901 tccctcggct atggaggtgc cgacgcctgt cgccgtataa aatcccggta tgcctgcacc 3867961 gcctgcacga attctctcag cgagcgttcc ttggggaaca agctctacct caagctctcc 3868021 gcttaaaaac tgccgctcaa aaattttatt ttcaccgaca taggaagcga tcattttctt 3868081 gatttgcttg ttagccagaa gcaaaccaag cccccagtca tcgactccgc agttattgct 3868141 gacaacggtt aaatccttta ctccctgatc tcttatagac aaaatgagct gttcagggat 3868201 gccgcacagc ccaaaccctc ccgcgatcag cgtatcccca tcatgaatca gtttcgcagc 3868261 ttccttgctt gatgacagca cttttcccat attgatgccc ctttcgtttt cttctacact 3868321 agaccagtca ggctgtaaat cgcgatcaca gcaaatacgg cagccgtttt aatgagcgtg 3868381 atcgcaaaaa tatcgcgata ggattgccgg tgggtcaaac ccgtcacggc cagaagcgtg 3868441 ataacggcgc cattatgcgg cagtgtatcc atcccgcctg atgccattga aatgacccga 3868501 tgcatcacct ctggcggaat attgtaagcc tgaatcgcct gtaagtattg ttctgacatc 3868561 gcgcttaacg caatgcccat tcctcccgaa gccgagccgg tgattcccgc cagcgcagtt 3868621 gtcgtaacgg cgccatttac aagcggatcg gtaaaagtat gtgaaattcc gctgctcagc 3868681 ttatgaaacc ccggcagcgc ggcgataatg ccgccgaacc cgtactcagc acccgtattc 3868741 atagatgcca gcaaggcgcc gccaattcct tcattcagcc cttccttcaa ttgggcaaac 3868801 acacttctcc aatcaaataa tatcgttgtg atgatgccaa tcactaaagc aatctccacc 3868861 gaccaaatag cagccgctga agaaatatca agcctgccga actcctttaa tcctatggaa 3868921 gaaaaatcaa atccattcgg ataccacttt ggcaggtaaa tggtgaaata tttattcact 3868981 gcaccgacga gaataagcgg gacaaaggca agcgcgtgcc gaatcgggct tttgtccggt 3869041 tcagccgcgg actcaatcga ttcaggagca ggagcattct gcgaatcaaa accgccatag 3869101 ccttcgccag atgcctgcgc tttcttccgc cttgattcca aatagagcat cccagctgcc 3869161 agcacaatca ctgcgcccat caaacccagc caaggggcgg cataaatgtc tgttttgaaa 3869221 aacgacgtcg ggatgacatt ttggatttgc ggcgttcccg gaagtgcgtc catcgtaaac 3869281 gtaaaagctc ctaaagcaat cgtacccggg atgaggcgtt ttggtatgtt tgcttcttgg 3869341 aacatgtttt tcgcaaaagg atatacagca aatacgacaa caaacaggct gacaccgctg 3869401 tacgtcaaga cagcacccat cagcacaatg gcaagtatcg ctctttttgc cccgacaagc 3869461 cggacaattg ttttcgcgat tgatgccgca agcccggcca tttcaacgac ctttccaaaa 3869521 atagcaccga gcaaaaacac tgggaaatac agcttaataa aacccgccat cttctccata 3869581 aaaattgatg aaaaaaaagg aagcacatgg cttggatctg tcagcagcac cgcgaataac 3869641 gcgcaaatcg gcgcaaacaa tatgacagaa aatccccgat acgccgtaaa catcagcaaa 3869701 cctaacgcca atagaatgat gatcagttcc acacacacat cccccgtttc cgcgaactag 3869761 aaagcgttta caaaaacctg tccgcatcgg ctgtttccgt cccctttcca tatgtacgag 3869821 aagcgtgggc caactattcc gattaaaaaa ggaaagctcc ttttttcgga gctttcctct 3869881 accattcatt tcattcctat taggatatca acatcaaccg taatatcggc tgatttcatc 3869941 tctttcagca ggctgactcg atctttcggc gccgaccagg caagcggcgt catcttgaga 3870001 agccagtgga tcgcctgctg gtcaagcgtt ttaacatagc gcagcctgac aggacggctg 3870061 tgtgctgcat ttgctgtaaa acgctcaact gctgccgtat tggaatacgt gcgccttggt 3870121 gaatcagtat ataaaaattg ccttaattct attaaatagt cgcttcgcgg cactactttt 3870181 atgagcatgc catcattctt cagcagtcta tgaaactctg cataattgga cggcgaaaaa 3870241 atagacagaa caacatcaaa ttggcgatca tgaaaaggag cacgcgccac atcggcaacc 3870301 gcccacatca gatctttgaa tgccttagaa gcttttaaga tcccgtcctt cgaaagatct 3870361 atgccggttc ctatcgctgc tttccctgca taatcaaacc cgcaaagcgc attcaaatga 3870421 gaaccctcac cgcaaccgct gtccaagatg gtgaatgcct catgaccaga tttgggatga 3870481 ctgatgagct ctgcaatcgc atcatggagc gggtcaaaaa aaccacattc tccaatcagc 3870541 ctgctcctcg cttcaaaaag ctcggcaccg taactggttt tgaccggctt cgtcagaaag 3870601 ttcacgtagc cgtgccgaga tagatcaaat gtatgtcctc gttctgtaca aatcaagctt 3870661 ttccctgatg ccgcatccat agaagaatcg cagagcgggc atcgaaacat gctgaaatca 3870721 actgttcgct tcatgataaa aaacacccca ttcattcatt tttagataaa tgaaaaaggc 3870781 atagacaaat aaacctaggc ctatctcaaa aattggccag gtctggcagt ttgtctacac 3870841 ctgtcattat ctataacgaa tgaattggat aatcatgaaa aaaactccct ttctgctgta 3870901 tgggtttccc cgtttccatc atacaacaaa tatccaggag ctggaacctt atagtgaaga 3870961 aaaatcagta ctgacatgct ggtatcccgc caacatcata tcagcatagc aatccagcat 3871021 gtttttcctt tattttctca ttttagaata taaattttat tattgtgaaa atagttaaaa 3871081 aggttgattt tcaaaaagtg aaaggataaa atactgctat catcttagaa aaagacattc 3871141 ttgtatatga tcagtaatat ggtctgattg tttctaccta gtaaccgtaa aaaactagac 3871201 tacaagaaag tttgaataaa tttgaacgag ttgaaaagga caagttcttt tctgtttgct 3871261 cttatttttc acactttctg cacttccaga atttgtgaag gataagagct ttttttgttt 3871321 ccataataac cctcatagga gttgctatca tgtacttttt actaaacctt gtcggtctca 3871381 ttgtgattat ggcagttgta ttcctatgtt ctccgcagaa aaagaaaatc aagtggcgcc 3871441 cgatcattac gttaattgtt ctggaattgc tgattacttg gtttatgctg ggaacaaaag 3871501 tcggaagctg ggccatcggt aaaatcggtg atttcttcac ttggctgatt gcttgcgcca 3871561 gtgacggtat cgcgtttgcc tttccgtcag tgatggcgaa tgaaacagta gactttttct 3871621 ttagtgcgct tcttccaatt atctttatcg tcacattctt tgatatttta acgtatttcg 3871681 gcattttgcc ttggctgatt gataaaatcg gatgggtgat ttcaaaggct tcccgcttgc 3871741 cgaaattaga aagctttttc tctattcaaa tgatgttcct tggaaatacc gaagcacttg 3871801 cggtcatccg ccagcagctt acggttttaa gcaacaaccg cctgctcaca ttcggtttaa 3871861 tgagcatgag cagcatcagc ggctccatta tcggatctta tctttcaatg gtgcctgcga 3871921 catacgtgtt tacagccatt cctttgaact gcttaaacgc gctgattatc gcaaacctgc 3871981 tgaatcctgt tcacgtgccg gaggatgaag atatcatcta tacaccgcct aaagaagaga 3872041 agaaagactt tttctctacg atttctaaca gtatgcttgt cggcatgaac atggttatcg 3872101 ttattttggc aatggtgatc ggatatgtcg cattaacgtc agcagttaat ggcattcttg 3872161 gcgttttcgt acatggcctg accatccaga caatttttgc ttatctgttc agtccgttcg 3872221 cattcctgct tggactgcca gtgcacgatg cgatgtatgt tgctcagctg atgggcatga 3872281 aattagcaac gaacgagttt gttgcgatgc ttgacttgaa aaacaatctc aaatcccttc 3872341 cgcctcacac cgttgcggtg gcgacgacat tcctgacgtc ctttgcaaac ttcagtactg 3872401 tcggcatgat ttacggcacg tacaattcga tccttgacgg agaaaagtca acggtcatcg 3872461 ggagaaacgt gtggaaactg ctcgtcagcg gaattgcggt atctttatta agtgctgcga 3872521 ttgtcggcct gtttgtgtgg tagaaacatt gagccatatc ccttttcgga tatggctctt 3872581 ttcattattg ataaatagag gctggcacct gcacatcccg gattcccgct gcataaggcc 3872641 ccaagtcata ctggccgaag acgatggcga tcccgtttgc cgtaaagtaa aacattgtgt 3872701 ctctgtttag ggttatatcc tctttcttta catcagagaa aaacagcaca tcgtgttttt 3872761 tgatatagct atataggtaa tctctcgttt tgctgacttt tgttttggtg ttcagaatct 3872821 gatccagcgt cacccgcttt tgtgctttca agtcatagtt gaaggactgg acagacgtta 3872881 gaccgtgggc gccccctgaa tagatataat tgagtgtttg aatgctgagc ttgcctgccg 3872941 cattgtattt gacgctgaag gatgtttgat attcccgttt taaagccctg ctgttcgcct 3873001 gcttttttgt ttttcaggta ttcctgatac gattgttcat gtaggctttc agctcttgat 3873061 tgattttctt ttcaaacgcg gcattcccga cgtgatgcac ttgtggatac gttaactcct 3873121 tgatcttttt gtacgtatgg gtgctgacag tcggtgtttt cgcttgaact gcttttaaag 3873181 atggggccgc atatgcaaat acagaaaaaa gcaagactgc aatgcccgcg gctttcagca 3873241 tgttattcca tttcatacaa tctactcctt tgatgtcgtt gtttatcatt cccttattta 3873301 agcaatacac acttttatag actgattaaa tcgaaagaag tttctaggtc taacagcatg 3873361 atttttccaa taaaaaaaga gacacaggat gtctcttttt ttactgtttg cgcccagaaa 3873421 tcgcttcatg aagggcttgt gccaaatctg tatttccgaa catctctaat accgcaatga 3873481 cagtctggtc cggaatgtgc tctgcttcgt gttttggcac gaccagatcg tccatggttt 3873541 ttttcaagct ttcattcagc ttttgctgcg gatacgcttt ggcgtacagc tccatcggat 3873601 caagatcatg gttcacgcac cactgggcaa acaccaaaat catcatattt tcatcgcgtt 3873661 cgtaagcttc agtgagctgt ttttcgttca tttgtcatgc tccttatgaa aagtatcttc 3873721 cttaaagata caggagccga tcaaattcgt ctatcccaat ggcgatgagc agcaaccgca 3873781 tcgataaatg ccttgctgaa agcggtgtag tcaggttcat ctttagccgt tacgatgcct 3873841 agcccctctg ttgtcccgac agaggattga agaaggtcaa ttccttcatt tgccgcaccg 3873901 atcgccttgt agtgattgta agcttctctg ataaacgcca tcgcttgttt gttgtctttt 3873961 aactccagtc ctcctgcggc atagacggca tcatacagaa cagaatcaac cgtcaggaac 3874021 gtgccgctgg cctcaagctg ctgtccgctg ccgcttgtca tataccccag attttgactg 3874081 atgatatcca ctgtgattcc ttcttgcttt aaggcttcca gtactgtttg cagctctttt 3874141 tcatgaaatc cgtttccggc gagtacagcg acttttcttg ttgacgcggt tttcactgta 3874201 cgggcttggc ttaacgcagg cgaagtaaga atttctttag atgctttacg cttcgcgggc 3874261 gccgccacgc ctactccttt ggcgatttct tctgctaaat ctgcatcgac attgctgaag 3874321 acatcaacga cctgccgctg tacgtctttg cttttgacct tcccgacctc gaagcagaaa 3874381 gcagaaatga tgtgctgttt ctccacagga gacatgctgt tccagaaaag cttcgcctgt 3874441 gagtaataat cgttgaagct gtcgcttcgc tggcggattt ttttgccctc gactttttcc 3874501 tgatagtgga cgtagccgcc ttcttcagct gtcgcaggcg acggatcatt gttttgcagt 3874561 gagtttttat gataagcgac aggtccctta ttgatcgtca tccggtgata gccgtcgtat 3874621 tggttgttat ggaatggaca gaccggccgg ttaatcggaa tctcatggaa gttcgggccg 3874681 ccaagacgga tgagctgtgt atccgtataa gagaaaagcc gcccctgcaa tagcgggtca 3874741 ttggtaaaat cgatgcccgg cacgacattt cccgggtgga atgcgacttg ttctgtttcc 3874801 gcaaacacat tatcctgatt gcggttcagc gtcatttttc caatgatctt caccggcaca 3874861 agctcttccg gccacagctt agttgggtca agaatatcaa aatcaaactt gaattcatct 3874921 tcctcatcaa tcatctgcac gccgagctcg tattcaacct tgccgccgtt ttcaattgtt 3874981 tcccacaggt cacggcggtg gaaatctgga tctttcccgg caattttttg cgcttcatcc 3875041 catacgagag aatgcacgcc gagcaccggc ttccagtgaa atttcacgaa acgtgccttt 3875101 ccttgttcat tgacaaaacg gaacgtgtga acgccgaagc cttccatcat tctgtagctg 3875161 cgcgggatgc ctctgtcaga catcgtccac atcaccatgt gggcagactc agggttattg 3875221 gcgacaaaat cccaaaatgt atcgtgagca gtcgcagcct gaggcatttc attgtgtggc 3875281 tcaggcttaa acgcgtgaac caaatccgga aatttgattg cgtcctgaat gaaaaacacc 3875341 ggaatgttat ttcccacaag gtcatagttt ccttcttcag tataaaattt tgtcgcaaag 3875401 cctctggcat cccgcaccgt gtctgcggag cctttagaac ccgcaaccgt agaaaaacgg 3875461 acaaataccg gtgtcttcac cgaagggtcc tgaagaaatt tggcccgtgt gtattccgtc 3875521 attggttcgt aaacctgaaa aaagccatgc acgccaaatc cgcgcgcatg cacaacgcgc 3875581 tccggaatcc tctcatggtc aaagtgcgtc attttctccc ggaaatgaaa atcctccatc 3875641 agcgtcgggc cgcgaacccc ggcttttaac gagtgctcat cctctgacac tcgcaagcct 3875701 tggtttgtcg tcattttctt cccgctgtta tcggtcctgt actgctcaag ctgctcgtcc 3875761 tttgagtgtt catttacacg tttgttttgg tcatcactca tgtctgctcc ccctttttaa 3875821 aacgaaacat tctacagcac atttacccgt ggcgttcttc atataaactg ctaatccgct 3875881 cattaggatt tttggtctac atataaatat gcggtcatac acatttgaaa taagccttct 3875941 tcacagaaag aaaggatgga agcgcttacc aaaaaagctg ttgaataggg gaggtcatat 3876001 catgcttgcc atactcggtt ttgtgatgat gattgtcttt atgtacctta ttatgtctaa 3876061 ccggctttcc gctcttattg ctttgattgt cgttcctatt gtgtttgccc tgatcagcgg 3876121 atttggcaaa gatctcggcg agatgatgat tcagggcgtt acagacctcg cccctaccgg 3876181 tatcatgctg ttattcgcca tcctgtattt cggcattatg attgactcag gcctgtttga 3876241 tcctctcatt gccaaaatct tatcgtttgt caaaggagat ccgttaaaaa tcgccgtagg 3876301 cacagcggtt ctgaccatga ccatttcgct ggacggagat gggacaacaa cctatatgat 3876361 taccattgca gcgatgctgc ctctctacaa acggctcggc atgaaccgtt tggtgttagc 3876421 gggaatagcg atgcttggtt cgggggttat gaatattatc ccgtggggcg ggccgactgc 3876481 gagggttttg gcttccttaa aattggacac gtcagaggtc tttacaccgc tgattcccgc 3876541 tatgatcgcc ggcattctct gggtgatcgc cgttgcttat atcctcggaa agaaagagcg 3876601 gaagcggctc ggcgtcattt cgattgatca cgcaccgtct tccgacccgg aggccgcacc 3876661 gctcaagcgt cccgctcttc aatggtttaa cctgctgctg actgtcgctc tgatggccgc 3876721 actgatcacc agcctgctgc cgctccctgt tctttttatg actgcgttcg ccgttgcctt 3876781 gatggttaac tatccaaatg tcaaagagca gcagaaacga atctcggcgc atgcgggtaa 3876841 tgcgttaaac gttgtctcaa tggtgtttgc tgcgggcata ttcacaggca ttctctccgg 3876901 cacaaaaatg gtggatgcca tggcgcattc tctcgtttca ctcatccctg atgccatggg 3876961 cccgcacctg ccgttgatca ctgcgatcgt cagcatgccc ttcacctttt tcatgtcgaa 3877021 tgacgccttt tacttcggtg tccttcccat catcgccgaa gccgcttccg cttacggaat 3877081 agacgccgct gaaatcggga gggcctcctt gctggggcag cctgtgcatc tgctcagccc 3877141 gcttgtgcct tccacctatc tattggtagg aatggcaggc gtcagctttg gcgaccatca 3877201 aaaattcact attaaatggg ccgtgggaac aacgattgtg atgaccattg cggcgctttt 3877261 gattgggatt atttctttct aaatgtatga gcttgatcgt agcattgagt gagtacgtga 3877321 tttacagagg ggagaagatc aaataggata ttatgagtga atagaagatt catgccaaca 3877381 acttctcatt acaatcataa gagcctgcta tattgcagca ggctctttca catttggcat 3877441 tatttttttg tatagcgcac ccagtcataa tgagcgtata gcggatttac accattgtag 3877501 gagccaagcc attcatcgac acccgtgcca ttccacaagt tcatcatgat ctttccaggt 3877561 gttgtcggaa tttggtttgt tgcagtatgt tttaattgcc cgtcgacata ccatttaata 3877621 gagtttggct gccaatcgaa tgcatacgta tgataggcat tggctgcatc aaacccgaga 3877681 tcaacaatct tctcatggtt tcctgcacca tttgtataat agttaaattg aaccttcgtt 3877741 gtgtcttttc ctaaaaattc gatatcaatc tcatcccaag gagttccatc tgttggacct 3877801 gtgtaagtga agaacgatga aacgatccct gtgtttttag ctggtttcat tctgacttca 3877861 taaagtccat agccatatgt ttgaacagaa cggttttccc cgcagtcaaa cttgttataa 3877921 gctgggcttg ttagcgctaa acgcatttca cccaatgacg tcattgatac gttattagcc 3877981 cgccacgtgc agttgaacat atttccattc gaataaccat ctgctttttg ccaaaaaccg 3878041 gagttatagc cgttaaaagg gtcaaaaaac gatccacctg tttgagctga ggcagtagca 3878101 gtgactgcaa acaaactcat aaacaatcca gtgacaagaa gcagcaacac tcgtttcaga 3878161 taaggcatat tggcattccc ctttcattga aagcgttttc tatgttgatc ttacatgatt 3878221 cttttaaaag ggaacatcgg tcaaaataat gataatatcg aatcttacta acttgaatcc 3878281 tgtaactatc atcatcttcc ctctgaaaaa aataaaaacc taaattacca tcagcacaga 3878341 cagagatgat ccgcactcat tgcaatttag gttttgcctg ctttatcagt aacaatccta 3878401 ccattttcat atgtgaatgt aagaaaaagt gaacacaagg aaacacaaat gtcagcgctc 3878461 tcattatgct tgtttaacta ccctttctat gtgaatggtt aaatacagca gctcgtcact 3878521 tgtgagcttg tgctcatact cccgctcaat gtaggtttgg attttcttcg tgcattcata 3878581 cgcgcgatga tacttttctt tcactgtatc cagcaaaaaa tcgtcctggc tttccatgtg 3878641 agtgccgtta aatagacgct gcgcgaaaaa ctttaagtgg gtgacgaacc gataatagtg 3878701 aagcgattct tcgttgaatt caatcttaaa atggtatttt acaatactca aaatctcttg 3878761 catgactttt gtaatgttga taatattggg catctcttca ttcagctcgg catttacaat 3878821 atgcagagca ataaagcctg cttcatcctc tggcagagac acaccagtct tgttttttac 3878881 cataaccaac gcttctttgc cgatcgcaaa ttcgtctttg tagagccgtt ttgtttccca 3878941 cagcaaggcg tttttgatat caagcccttt ctggttgcgc tggatggcaa agttaatatg 3879001 gtcggtcagc gacacataga tgctgtcgtt gagctttttg ccgagctgta attttgcgta 3879061 gctgataatc tcttcggata cttccataca ctcgatcggt atatcataca aaagggtttt 3879121 gaacttttct gatacatcct tgttatcgag cgtgaacact ttctcaatgc gggcttcatc 3879181 gacatcatcg ccggactttt tctgaaacgc gagccccctg cccatgacga ccaattcttt 3879241 cccctgttca ttgaccacgc tgatcacatt attgttgatc accttcgcaa ttttcatggc 3879301 atgtccctcc aaatctacta agaacagact atatcttgat tgtacattct ttttgtacta 3879361 ggtcaatatc atcagggaaa gacggaagct ggtcagtaca attcactccg tacctgctgc 3879421 ccgggctgtt tttgaagcag cgcctccaga tggcgttcaa atgatgcctt gtcagctttc 3879481 tgctttttga caatgctgtt catgatttta atgctttcag cactgtattg tgtatattgt 3879541 tttttcagct gatccagctg ctgtcttgtc ttcttcgcgt ttttcggtgt gacttggttg 3879601 atgagtttga tcatactgtc tgcggtctca aaaaaaccgg ctctattttc tgtcagctgc 3879661 tgaatttcga tgcggctcat atcttgatta cgcgtttttt gaagcaaggc aaccgcctcg 3879721 ctgttttgtt ttttgagcga tttgttctca agcttaatcg attcgagatt ctccttcgca 3879781 atgtctgctt cttcttcagt catgctgatt cgcacgaagt attctggatt gccgattcca 3879841 taatcaaatg cttcgctcac ttgtatcatg gaactgaaca caatggccag ctgcctgtcg 3879901 cttgcgaggg cttggaaatc ctgctttttc ttactgctca tcggtttggc tgcggtttgt 3879961 tttactgtct tttgatcaca gtctgcgaac atctgagcct caccttcact ttcgcatgcg 3880021 ctcatcacaa gaactgtgac cagcaggctt atacacaagc ctattcgcct catgctctgt 3880081 ctcctctctg ctgaatccct tctggaaaat accataaaat atagttaaat ggtaccagat 3880141 gcacctaacc ccagcaataa atcaaaagta tgatttgaag cgaaaaaaca taaatatttt 3880201 gtaaaaattg acgtgcattc cattcttttc aggcccattt ctcgtacaat agaagtatcg 3880261 ttaccggaga ggggctctga tgatgaaacg ttttacgaaa caagaaaaca gctgggtgtt 3880321 atatgactgg gcaaattcag cttactcaat tgtcgtgacc accgcggtat ttccgttatt 3880381 ttataaatca gcagctgcgg aaagcggtgt cagcgccgct caatcgactg cctatctggg 3880441 ctataccatt gcgatttcaa cgtttattct tgcgatgctc ggccctattt taggcacaat 3880501 cgccgactat gaagggtgca agaaaaagtt cttcggtttc tttgtgtcag ccggtgtcgc 3880561 cagcaccgcg atgctcgcct ttatccctag tgaacattgg ctgctattgt tgctgtttta 3880621 tacggtatcg gctatcggtt tttccggcgc caatgtgttt tatgatgcct ttctcgtgga 3880681 cgtcacgcct gagaagcgga tgaatctcgt ctcggcacgg ggttttggct taggatacat 3880741 tggaagcacg attccattta tcatcagtat tgctgtcatc ctgctcgcac aagcagagac 3880801 tattccagtg tctgtatcgg ccgcaagcca gctgtccttc ttcataacgg ctgcctggtg 3880861 ggggctgttc accatcccaa tgattaaaca tgtccatcaa cgctattaca tcaaaaaaga 3880921 acctcatatt gtcatcaaca gctttaagcg gctcggccaa acgatgaaac ggatcaggca 3880981 ataccgggca cttttcctct tcttgctcgc ttatttcttt tatatcgacg gagtcggcac 3881041 gattattacg atgtcgacat cctatggatc agatttaggg atcggctcct caagccttct 3881101 gatcatccta tttgtcaccc aggtagtcgc cgcgccgttt tcgattatat acggaaaact 3881161 ggcagaacgc ttcacgggga agaccatgct gtacgtcggg atcgtcattt atatgatcgt 3881221 ctgcgtgtat gcctatttta tggagacaac gcttgatttc tggatactgg ctatgcttgt 3881281 cgccacctcg caaggcggta ttcaagccct aagccgttcc tatttcgcca agcttgtgcc 3881341 aaagcgccac gccaatgaat tctttggctt ctacaacatt tttggaaaat tcgcctcaat 3881401 tatggggccg ctgctcattg ccgttaccgc ccagctgacc ggtaaatcct cgactgcggt 3881461 gttcagcctg atcattttgt ttgtgattgg tattgtgatt cttgcctttg ttcccgagga 3881521 aaccagcaca gatgtcagcc agcagcaaaa tgacctgccc ctttaactgg gagcaggtca 3881581 ttcatcattt attcgcttta ttcaccttca gctgtttccc tttgacggtt gtgttcttca 3881641 tcactttgag aacatgaggg cctttaccat ttaaaatctc aacgtatgag gcgttatcca 3881701 tgatcgtgat gatgccgatg tcgtcagctg acacaccgtc aattttggca atcgttccta 3881761 caaaatcaac ggctctgatt ttctttttct ttccgccgtt aaaatacagc ttcataatgt 3881821 ctttattcag ctcttcgctt ttgtcctttt tgctttccgg acggtcattc agtttagcta 3881881 gaaattctgg tttcttcctt gccacttcct cttgagaagg tgcttctatt ttttggattt 3881941 caaatccgat atattcttca atgtcggcta aaaaccgttt ttcgaaggcc gtgacaaacg 3882001 aaatggcctt tcctttgttc cctgcgcgtc ccgttcggcc cgtgcggtgg acatagcttt 3882061 ctttttcaag cggcagatca tagttgatga caagggagat attttcaata tcaatcccgc 3882121 gcgcggcgac atccgtcgcc actaagtaac ggtactcgcc acgtttaaat tcattcatga 3882181 cgtcgaatcg gtcttcctga atcattccgc cgtgaatttt atcgcatgga tatcccaagt 3882241 catccaattc atcggtcagc tgattgacgt gctccttcgt tcggcagaaa atgatgcagc 3882301 tgtcgggatt ctccgtcatc agcacatctt tcagcaatga aaacttattc tcttctctta 3882361 cttgaatcac cgcatgttca atatttcttg tggttaggcc ggccgctttg acctcgatat 3882421 gctcggggtt ttgcatatat tgacggctca gcttctcgat atcctgcgga agcgtcgctg 3882481 aaaacagcat cgtcgtacgc tcagtcggca gatgcttgat aatcgcctcc acctgctcaa 3882541 tgaagcccat attcagcatc tcatccgctt catcaatgac caaataagag agacgatcca 3882601 acggcagcgt gcctttttcg atatgatcca gaacacgtcc cggcgtgccg acaacaatgt 3882661 ggcttttttg cttaagctca gctttttgtt tatcaaagga ggattttcca aatacggctg 3882721 tcgctttgat ccgtttaaat cgtccgatgt tcgtgatatc ttcctttact tgcaccgcaa 3882781 gctcacgggt cggtgttaaa ataagcgcct gcggcttgtt ttcatcccaa ttcgccagct 3882841 cacagagagg aatcccgaac gaagccgttt tcccgcttcc tgtctgtgat ttgacgacaa 3882901 gatcctttcg ttcaagggca gcggggatca cactctgctg caccttggtc ggttctgtat 3882961 atcccagtcc ttccaatgct cgtaaaatgt catgactgat ttgatagttt ttaaaatgac 3883021 tcatgtataa actcctgtct cttgcagatg ttctcattat actctaattg accaaggcat 3883081 atgtgttttg tcgaaaaatg atgtattaaa agccagcgat tccctggcgt tttagctcct 3883141 gaacagccaa tcgcgccagt gcgtcggccc ccgcgcgatt cgggtgcagc gtatctccat 3883201 ccatataaag cccgagtgtt ctttccggac cgatcgatgt aaagtatgcc gagctgagga 3883261 catttaagtc aatgagatat gttttttcct cttcggccaa agctaaaata gaggccctgt 3883321 accatctgtt tacagacgaa tggatgcctt cagaagtaaa atcggttgcc cggccctgag 3883381 gcgttgatag gatgacgtcc gctcctttcg cttttacctg acgaatcata tcacgcatca 3883441 cctctttaaa ctccgcttca gattctttat gcttcggatt tgtgtcatta atgccaagct 3883501 gcaacataaa ataatctccg ggtttaatat acttcagaat cgcctcaagc tgtccatcat 3883561 ttctgaaccc tctcgcgatc tgcccgccag acgccatgtt tctcacttga aaggtgtgtt 3883621 tatcgatata gtgaggcagc atctgccccc agcccgcctg cttgctgctg ttgagcggat 3883681 aataattgca caccgtcgag tcgccgccga cataaatggt tcgattcgtt accggctgat 3883741 cagacaattt ctttattttc aaggcgctga gcgtaaaagc ggtgcctgcc tttccctctg 3883801 tcaccagcag attcagctgc ccgtcggtga cgggaatttg gaacgtatcc tccgcgccat 3883861 cccctgtcat attgatgacc tgaaacacgc cctccgctgc cacactggcc cttgccgtat 3883921 tgccaagcgt caccttcacc tcataaaggc cattcgggag atcaacatta aacgtgttat 3883981 tgcttttcgt cccatacgct aaaaactgaa ccgcatcact cttcacacca gccccggatg 3884041 ccgccacatc cctcatattc tccggtgttt gaaaaccgta gccctttgac cggtcatacc 3884101 gatcagacgc cctgacacca atataaccag gctccatcga accgcttcca aagtcaaact 3884161 gatacacctt cggctccgcc gccttcacat tctcaatccc gccaaaacac agcatcagca 3884221 tcatcacaaa aaccgctgcc atccattttt tcatcaagac tccccctcta tgaaaacgaa 3884281 tacattaatg catactcggt gattgtttct ttatgatgac tgaattaaga aaaaaattgc 3884341 gttgaggaat aaaaatgagg ggagagtctc aagaagggga aaatcagtgt gacttcttgt 3884401 cacacttgat cacatcccaa cctccgcaat agaagcttat ttggttttct tcgtcataca 3884461 cataataacg gagtctttcc cattgatcgt cagtcggtac aatctccaat gcaaccgaat 3884521 cgatggattc aaggtcatcc agctttgatg cactaatgtt ttcaaaccgc aattgaatgt 3884581 cacaggtttg agcagatcgt tttcattcaa acacaggaat atgaatataa cgatcatctt 3884641 ctttcatata gaaagaaaac tcgtttaatg taaatggacc tgtatcctca tcagaaagat 3884701 gctgtttcaa tttctcgtat tgtgtgatat tcaaatgaat tccctctatt tatatgattc 3884761 accgccaatc atataaatgt ccacagcatc gtattcaaac catatgatcc gttcgcctga 3884821 gtccgttagg cattggagct tcccttctga aaaatagctt ttatccggtt gaggatcagt 3884881 gatcagaaaa acatcatcat tgatggaagc tagcagaaag agaaaatctg caatatcccg 3884941 gtctgcttcc tgtaatatgg attggaaatg gaattccctt ttggccagct tcgtcacctt 3885001 gtaagcatga ccttcaaaat actcggacag gtcttctata aatgaaccag tcgttattac 3885061 ctgtatcatg attcgatcgt aggcaagccc tgcccaaaaa cgataaaacg actctgcatc 3885121 ttcaagttcg catgccataa cggtttggtc aggcttaagc tcgatcatgt ccaaattgcc 3885181 aatactgctt atagaggtta tttccataaa atcttcccct tatcagttgg atagcgcaac 3885241 gcaaatctct tgtctgactt gttcatacaa gagaatgtga tgatacagat ccttatcgtt 3885301 tttgatcata tccggaagta tgtcaggata cagctcaaaa aagcttttct ccaacgaacg 3885361 ccgctgatgc cggggtatcc ttttattcgc cagcacataa tccaaactgc cagcaacaag 3885421 cataaaaaac tcatagattt ccgcttcaaa gccgtacaat tcatcagggt actgcttttc 3885481 ttcaagctct cgctgtcttt ttctcagttt ttgaagcacg ttgatcctct cccttccgca 3885541 ataatctcat ttatttcgaa acagaatagg cggatcatta tctatcgcct ccaacagctc 3885601 ttcaccaaac acagtgattg cacatttcca cgggtctccc aaaagtcccc aggagaagtc 3885661 ctgatgaaaa aagaaataat agtctccatt tggaaatacg ggaacaggcc attcgccaaa 3885721 ttcatcctta ggcattgcct gatgaggact aaaggtatat ccgtcatgct gccaatctag 3885781 tgcgtacatt acatcgttct ttccagtacc taattgaaat gcttttaaaa tagaagtctc 3885841 taaatcactt agcactccgc tcacatcatt atgaccagct ttactgctca tcgcgcttga 3885901 gatatcaaac actcgatatg gatcaggcgg gatgatgtga tgacatctgc ttccgggctt 3885961 ccattttatg atcttgttca cttctgacca gatgcggtct tgttttgtct gacttaaagc 3886021 gcgccaattc atcataatct catccctaca ccttattgga tatcctgctt ataaacacca 3886081 gaagaggcca ctgcgtaaac agcgtaactt gtcagtttca gctgttgaac atctaggcct 3886141 tcaccgttcg aatcacagca tgttatctct tccatctctt gactcacatc ggcagaaatc 3886201 aaataaagag acgacttaag gtctgcactg taacaattga acgtcccaac caaaaaacct 3886261 tcttcggata tcgcgagctg atcaaatgct tctgagtccg gctctttatc cgacagaatc 3886321 cacacccgtc tcacgaccgt ttcatcaaat gcggcaatga ctgcatctcc gtaatacagc 3886381 atataaatca agccgttttt ttctgcaagt ccataacaat catctacagc aggcgcatcc 3886441 atttcttcaa gctttctatc aatgtgtatt tccttctgct gaccatctaa cgtaaaacac 3886501 cacacactat ggccgttggg attctcatca tgataaatcc cttcatcaca taaaccgacc 3886561 caaagctgtt gtttctaatc caaaagacag caggaaaccc ctgaaggcaa gtgaaaaaca 3886621 cttttcaccc ttccctcttc tgaaaaaacc tttaccttcg gctcgtacga ttcgtaataa 3886681 acgaagacat agccatctgc acattgttga aagagcagaa tatcactgta tgaaatctgc 3886741 tctttcactc taaaatcccg aacatcaccg gaaggatcat agattgtaat ggtgatacca 3886801 cctttcaacc cttttccaat gtagacacgc ccctgtggat cagcatggaa aaaacaatct 3886861 tgggtgttct cgttgatgat tttattcaat tttaattttt tcattggtta tgctcctagg 3886921 ttcgaaatga aatgataaga ataaaccatt tattagctat tagtaacgga caacctagtt 3886981 tcattaatcg ttttgggata aatctacttt ccaattcagc cttaaatcat ttagtgttta 3887041 attggtatgc ataaaacgat tgatcatcaa agcgaactgt ttcagcttct atagcaatca 3887101 gcattctgtt catgtcaata agaaagttag catttgattg atactccgga attatagaat 3887161 ttgatagatt cccgattcct tctggatgat aactcatctc aaatacttgc caattgtatt 3887221 cttccggatc tattttttcc aatctcatgt cgccaacatc tgcactataa taagcggatg 3887281 ccacattttg aaatgaaatt ttatgcgtat attcaccttc atcttcaaaa accttaatat 3887341 caagtgagag ttctttttta aacacattaa aatctaaatg aaggacactg caccccttat 3887401 ctatataatc aacccattca ttaatcgttt gatacattgt catcccctgc ctctttttaa 3887461 acaataacgc cttgccacca agcagaaaac aaattactcc gtatattgtt tgatccaatc 3887521 atttaaatca tctgttgaat gcaaataagt ttctgatgaa tctttcaaat caatcccact 3887581 tagaaggatt aacatatccc agactctatc gtcttctact tcggggtcat ccgcataaac 3887641 ataagttcca gcccaatccg acacttcttc tcttgttgtt tgtccattta agacactttt 3887701 gattttattt atgcattcta ttagatttgt ctcgctcaat ttgatcacca cgtattcaag 3887761 tactaaatga ttttttatta gtatgcaaag caccgtactg atatttagat attgaagctt 3887821 tttccgtaaa agatatgttc caaaaggttt ccaatctacc aataaacaag ctcacatccg 3887881 tattccgtgt gcaatataca taaaccaaac tggcacttag gctcaaccaa aataaaacta 3887941 tgattgagaa tcccttcatc gaactcaata cactccaata agcagtcaag gtgctcgaga 3888001 cattttccaa aagaacaaac taacgcacca atttcgctgc tgtattgatg aaacagcaga 3888061 acgtcccggt catcgtaagc aacatatgac tgagatattt tccagatcag ctgtttcgct 3888121 tccgtttttt cgagggcatc aacctcacgg gtgttggctg gtattgaatt tgataaaacc 3888181 agctcaagca attgcctgct ttgcgccaga tcagcaaaac gataagtgaa gcctctttct 3888241 gcacaaggga ctagtttttc tttgatttcg ctcatcaata aacgtctttt attctcggcg 3888301 agtttttcga tcaatctttt ttgcatgagc cgcattccct ccgctgtcaa tttctcaact 3888361 tcttttaaat tgattcatca ttctcttgtt ttcgttgtcg ttcatgttta gatttgttct 3888421 aaaaaagctt gtatcgctta tcgatacaag ctttatcttc aactgcttaa aactcaccca 3888481 gtgggctttt cacaaaacgc tgggaacctt tttggcaaat cctcttcatc ccaatcaatt 3888541 ctatattttt agattctttt gtcatacaaa taagagagga tggtaacatc tcttatttaa 3888601 tgttccatca ataaatgccc catttttatc caatgcagaa attatttata attaaggaag 3888661 tttagaagga ttttttgtat tttcaagatt taattttaaa gcggtcacaa aagactctag 3888721 cttttcttca ttacaattaa tttcgaacaa gttggagttc gacttacttt ctttataatc 3888781 atcaaatata attttaatct taattctgta atttccgttt tcttgatcaa tactaagaaa 3888841 taagaatggt tcaatagtct ctaaactgat actgtcttga tttcctttta tcatagtttc 3888901 gatcccagat atcaacacct tatattcact ttctaataaa acagcagaaa aatcgcgaac 3888961 gacggctttc ttattttcca acaattcaaa tacagataaa ataaatggat catcgtccaa 3889021 ctcttgatac cttctcggtg ttaattcaag ttctatacaa tcatctttta ttttggccat 3889081 atttcctcct catttaaagt ttaagtgagg gtagttgtca tccccccctc gcttaacctt 3889141 attaacgcct tctcttagat ttatttcctt ttccgtgtgt atggaatacg tgtttagaac 3889201 ccttagctct tgaacttcca taagctgtga ttactttacc ccttttattt aaaacaactg 3889261 tagctttttt tccaacatat ttcgttgccc cattaggttg ttttattact tttttagggc 3889321 ttcgcacagc attcagtttg gcccttaaat tgactccacg gcctccattt cttcctatag 3889381 attgattaag tccatgtctt gtatgacctg tgattttaac tgccttcttc gtaaacttat 3889441 aggcgcgact agcaccctta aatatcttcc caggaccaaa attagaagca gctgcccaag 3889501 cagcaccttt ccatccttta cctgatttat atgccttata tccatcatag gctgcaaatc 3889561 cggcatttac cacaagccat acccaatgcc cgtccggatc aacattcatc actgggttat 3889621 tatttccata agcataccca ttctgatcca atgaatctcc gtcgctgccc gggtctgggt 3889681 cgagcgatag gaacacgccg tttcttggct cgtagtagcg ggccatgaga tagtacaggc 3889741 cggtttcttc gtcgtattgg tagcctgcgt agcggtagcg attgtctttt acttcgtcgc 3889801 ttgcttcggt ttttgttgga tttccccatg cgtcgtattg atacttggca acggtttttc 3889861 cagtgctgtc tgagatcgcg atgatgtcgc cgtgagcgtt gtagtgatag aaatatttct 3889921 taccattttc tgtgtaggat aacagctggc cgctgtctcc gtacgtgtat gattttgtga 3889981 cgttgttgtc cgcgtctgtt tcatacaaga cgttcaagct gtctccgtcg tagaagtagt 3890041 tcgtgacttt tccgttgacg gttttttgga ttctgtttcc tttttcgtca tacttatatg 3890101 ttgcgaatgg cttgtcttcg ccttttttgg taacggcggt caggttatct tctgcatccc 3890161 acgtatatgt gaatttgccg tcggatgtgc ggttgccgtt tttatcgtaa gagatgcttt 3890221 catcattgac ttttgtcagc tggttcatga tgttgaagga agcgttcacc gttttgcttg 3890281 agccgtcttt tatagttgta acggttttcc ggtttccgaa tccatcatat gtgtattcaa 3890341 taacagtacc gtcttcatgg gtttctttga caagctgatt cagcttccca tactcatatt 3890401 gcaccttgcc gcttgctgag ctgtttatcg ttgtgcggtt gccgttggca tcatattcat 3890461 agctttccgt cagaatgtct ccgccgtttt tgtcaccgat atgcagcgag cttacaaggt 3890521 ttctttcgtc atatgaaaaa cttgttccgc cgccgttgcc cgtaataaag gtttggacgt 3890581 ttccattttc atcataatca aatgaatatg aggatgtact gtctttcatc tcaatcattt 3890641 gatccagctt gttatacgta aattgattcg ttcctttttg gtccccatga atccacgaga 3890701 aggttttcag cttatcggag tcactaggat atgtccaagt ttggctgccg ccgcggtctg 3890761 tcagttcggt taaacggttt ttgttgtcaa atgtccgttt ctttgtggtg ttctgctctt 3890821 tattgacgac cgacgtttca tttccatttt tgtcatacgt gaaaatgtac ttttctgtac 3890881 cgttatacga ctttgatttc acccggtctg ttccatcata agaaagagac acttcgttgc 3890941 catttggtga aatggttttg gtcaggttgc tgttggcatc atattcgctt gctaacacat 3891001 tgccgagagg gtcagttgtt ttgacaagct tgcccatgac atcatattcg aatttatagg 3891061 tttgatctgc tcctgcccgg atggttttgc ttacctcatt gccttcctta tcatagctgt 3891121 gaaggataga cgtgccgtta gagagcgtca tgtttgtcaa ttggtctgcc tgatcatacg 3891181 tataggttgt tttttcacct tttgcatctg tttcagacgt tttcttacca gtttcatcgt 3891241 aatcagttga agtggcgtaa cctagttcgt cctcttcctt ggtcacatag ttgccattac 3891301 tgtcatacgt gcttttagtc agaaggcttc cttcaatcaa acggatatca tcaaaccaga 3891361 ctgtgcctgt cgcactcttt tggaacagaa tactgatatc gactttattg atcggctttg 3891421 ttttagggat gacgacagct gctcggttcc attcctgtgt tccagaaggg aatttcgcat 3891481 tgtagatgcc tgtgctgccg tcagcgtaag tgacattcgc ctgcagagaa tagtcttttt 3891541 catctgtaaa tttgacgctg cttgctttcg acattcctgt cagtgtgaga taaaccggtt 3891601 tgtcatttgc gctttgccct aagacaacgg tttgttttgt tactgatccg gcttgggacg 3891661 cactggtccg ggcagctttt aatgatacat catcattaaa gccttcttca gaatcaacgg 3891721 atgctccgct tacattccag ttttccgttg ctgatgtgaa gctgctgttt tgaactgggt 3891781 tatagcttga tgatacttcg cctttttcca gctggacttc atcaaaccat gcttttcctt 3891841 tgccatcttt atctttatga tcgacttcca tatacacaac agctttgcct gcattcgctg 3891901 gagtcgtaaa agtgatttgc cgttttgtcc agtcattttt tccggctaat gcactgtatt 3891961 cattgtgaat ccattgaatt cgtttttgat ctttgtctcg caaatcaatg ttaaaatagg 3892021 ctcttgattt cgcaagatct gttttgattt tcccgcttaa tgtataggtt gtattcggct 3892081 ccagctcaac tgtttgtgtt gctgacgaat acccatgatc tgttccggca gacgttgatt 3892141 ggctcaagac ctccaatgcc tttgatccgg aaagaactcc gcttttatcg gcgatgactg 3892201 aaattttgcc gctgtcttta gaggcagtca gattccagcc ggatttttga gcttcaaagc 3892261 ttccatcttt caaaatatta gttgaagctg ataaatcttt gctcgattga atctggtttc 3892321 catatttatc ataaacagct gctgacgatg attttccgct ctgatcggtt tcggatacag 3892381 catccagtcc gtcataagca atatccgtga cattgccctc ggtatccttc atctttgtga 3892441 catcgttgtt tttgttgtat tcgtatgtct cagttccata tgcatcttta accgacgtaa 3892501 cgttgccatc tttgtcatat tgatagcttt ccgttgcttt tccggtgccg acgtcatttg 3892561 gatctacatc ttctacaaca ttgttgcctt catactttgt attcgttgta atttttaacc 3892621 cttccgcatc atcaatgacc tgaatcggat ttcccgcttc attatagcca tactgtactt 3892681 tccggccatt tggctgtgtc atgagaagcg tctttttatc agcatcatag ctgtagacat 3892741 atgtttcttt tttagcgttg atcgcttttt cgagacggtg accgctatac tgatattcgg 3892801 taaagacagg ctttgcttcg gtactgttag ctgaatattg tttgacaagg cgcccttcac 3892861 tatcgtagtc atagcttgtg acagtcccgt ctgtatctgt aaccttcttc agcaaatcat 3892921 tctcatatga gtaggtgact ttcttattct taggtcctgt gatggacgtc acatggccgt 3892981 tttcatcata ggtaaatgta agcttgcggc ctgatgcatc tgtaatggcg gtcagttgat 3893041 ttttgtcatt gtaagtatag acagttgcat tgttatggcc atccactacc ttttggagtt 3893101 tgccgccttt tttattgaaa taagcgttgg tttgatcctt tgtttttaat atgaactgat 3893161 cagctgtttc tgttaattca agatatacac cggtcggcgg ctgatacgtg ccatcggctt 3893221 ttttcgtgaa tcgatgtgtc gtagcgtctt catcgatata cattgccccg ccatccgttg 3893281 agatgacaga tgtttctgca tcagcatacc agccttgtcc aaataagtga tcagagctgt 3893341 caagactgtt gtaggttctc gataagccaa gtcccggacc gcgtccatca attgacaaat 3893401 cttcttcatt cacaatgaca ttgcctgtcg caccatttaa ctggccgctt gggatatcaa 3893461 tgatagacca gtactcttct gtacctagga attctgcgcc ttcatggaac gttgggttaa 3893521 agggcgccgt tggaatcgtt tcaccattcg catcataggc gacaagcgtg aaagaataat 3893581 tcttcttccc tttgtaattc ccatttgcat tgttatagac aggtgatgga tcgagggcta 3893641 attccccgcc ttttccatct gtatgaagct tatagcttcc ggctttgatt tcctcagaag 3893701 tcggccagat gtttttattt tgggttgtcc aatgatcagc atcaccaaca tcaaaggact 3893761 gatattcttt accgttgtaa atgttaactt tatagccctt cgcattttga accttttccc 3893821 atatcaaatt cacataaccc gtttgactcg attttgtatt tgtatacaaa tagccagtta 3893881 cattctttgg cctagcgata tcaggaagtg ccggggtagc agccggggat gcaatggctt 3893941 cgccgtcttt gttgtatgcg ataattttaa acgagtaatt tcttttggct ccatctcccc 3894001 cggcgttttt ataggttggt ccgggattga tcggcagctc tgctccgctt ccgtccttta 3894061 ggtgaagagc atattttccc gccttgattt ctgcacttgt cggccagatc tttttccctt 3894121 ttgtggtcca agacgtctga tttccgagat caagtgtctc aaagcctttc ccattgaaca 3894181 cctgaacctt atagccggtt gcaccggata cagctttcca agaaaggtcg aagtatcctg 3894241 tggcattccc attattgtag ccctttgctg acggtgcttg tgcttttcct acattaggga 3894301 taacgggctt tgccggtgcg gacatcgctc cttcaccttg gtcaaatatc gcactgacgc 3894361 caatccaata gtttttgctt gtagcatagc ttccgccgga attcttatag accggggatg 3894421 gatctaatgc caattcagct ccatccttgc cgtccagatg cagtttatat ctcttggagg 3894481 caatttctgc gctcgtaggc cagatttttt taccttttgt gctccacgac gtgacgttgc 3894541 ctgcagaaat cgcttgatat tccttaccat tgtaaatcca taccttatat ccttttgcgc 3894601 cttcaacctt tttccagctg atatcgaaat aaccagtgga atcgccgttg tgataggctt 3894661 tgattgtagg tgtgtttccc tttggaatgg tatacgtcac ttcaatatat ggtttattgg 3894721 cggagttcgc tgaagaaatt agttttttcc aatattcctt gccgtttccg tttgtatgaa 3894781 gcttaaatcc atagttggcc ccgccggagt tccatgactt tacagcagcg gtcacatcat 3894841 aactcgccca ctgtccttta tggacgtcgg cttttccgat atttttagat gccggtttgg 3894901 tgttccatgt cacttttgca ttatcataat tgctgttgac cgtatccagc caaaggccgg 3894961 ttgcctttgt tccataatag gaatgggcta cgtatgtttt taatgtagct ttagtgacag 3895021 tcatattttg aattggcttt aggttgttaa atttcatgaa cgcatagttt gtgcctgttg 3895081 ttttgtcata atagcccgtt ttcagtacat aggcctttaa attagcatcc catttttgtg 3895141 aggaggccga atagttcgtc gtcgggtagg cactcatgac aaacgtatcc gatgaaacag 3895201 ataaagaagt tgacgggtcg atagatactg gatatacgcg ttctgggtct ttcagccagt 3895261 tctcgtctgc cgtaagatga agcaaatacc cttcttcatt cttttccagc ttatagctga 3895321 ctttgtctga ccgttcaacc tcgccggaaa gctcatctag ttttgaatcc gtcataaaag 3895381 gcttaggcac agaaaaaaca acttttcctt tttcatcaga aaaatcaatg gatccatcct 3895441 cttgttcttt agcctgcaaa tcggttttta actgaaatgt aaatgtgttg tatccattat 3895501 actgatgaag gactaaatct tcttttatgt tttcattgaa tgtgaaagtc tgaagatcaa 3895561 tattcggaaa cacatccgga tacacaatct cattactgtc agtcttataa tctgctgagg 3895621 tatctttcgg agtaagtgaa gttttattcg ggcctttcgc ttctgctagt gaatatgtaa 3895681 ccttatggtc attatgctca aaagtcgcat aaagcccgtt cttcatttgc ttttgaaaat 3895741 ctgaattcaa aatagcgttc tctgtctcga cttgtttgct tgtcgactct tttaactcag 3895801 gagaaatgtc ttcccagtcg gcatccggtg tttcctttgt atgaatagga tcaaggtata 3895861 cttcctgttt atagacaccg tcaccttcat aatagagttt tgtattttct gttctttcag 3895921 aggtgatctc accctctttg tttatatctt ttggatcaaa aggtacagct tcctcagttt 3895981 gttctttctg aagagtttct tctggatcat cggcagcaat acggtttcca ttctcttctt 3896041 ctgtagattt tgctagtaca tcggctggca ctaatgaaat cattaaagcc aacactaaaa 3896101 atgctgcaat gaacctttta aagtttcgcc tctttctttt tttcatttcc tctctccttt 3896161 tgtaataaaa gtaatattta ctcaataatc ttaactagac tgaaatatca ttacaatatt 3896221 tttctagaaa atttatctta ttttaaggat tagcgagagt caattgacct aaaacaaaaa 3896281 aaggccgcat aggccttttt acatttttta ttgtatttgt tcaatatccg taccctcagc 3896341 tgtcacattc gccttcccct gcctcctgac aagcgtcaag gccatgcccg caaagatcat 3896401 tacgatgcca agcgtttgat agaggtcagg gcggaagcct gtgaagacgg tatcgagcac 3896461 gatcgcgaca gcggggtcga gaaatacaat gattgaaata aatttcgttg ataaaaatcg 3896521 taaactgtca aaaaacagca aatatacaat acccgtatgg atgatgccgg tagataccac 3896581 cataatccag tttccctgag ataggtccgc aaaagcgcca aagtgaataa acggaatcag 3896641 gatgataacc cctaaacctg tctgcaagaa ggtggtcgtg taaggactga gattgtgaat 3896701 gccttttccc aataaagtgg tgaacgcata aaacagtgcg gcgagaactg cccatatgat 3896761 ccctgatccc atcagctgtg tcaatgatgt gctgccgtta atcccggaaa tcagcgcagt 3896821 cccaagaaag cagatgataa tggagctgac ggagatcaca tttaatttct ctctgtagaa 3896881 gaagctcccc agaagaagaa caagcaccgg cgctagatga taaacagaga tggcaattgt 3896941 aacggacgtt tcttcaaaag acttaaataa gaacacccag ttgaatacaa gaaagaaacc 3897001 gcacgccaat gtttgcagca cgtctctctt gctccatttt tcagttttat actggccgga 3897061 cgccagccag caaaagccta aaaacagcgt cgcgcaaagg cagcggacaa agaccaattc 3897121 aaatgacggc agattggtat gctctgagaa aaagccgatg gagccgaaaa tcaccataga 3897181 gatgaccatt ttgattacgg ctgttgattt ttgttttgac gatatggaag gatcctgttg 3897241 catcaaacgt attctacctc caatactgca tagcataaac tgttttttgt gaattcagaa 3897301 atctacacat agaattcctc ttttttacat gtagatatta taacacttct attctaaata 3897361 aaaaaaagcg cccaagggcg ctttttttac aaatctatcg aacaatcaaa accgggcatg 3897421 ttgataattg agacacttta tggctgacgc ttccaagcat catttctttc aggccgctga 3897481 tcccccggct gccaactaca atcaggctga cgcctttctc ttttgcgtga tttagtatct 3897541 catgcgccgg ctcgccattc gcgtaaatgg tttcagcttg aacgcctttt tcggctgctt 3897601 tttcttttgc attctcaagg attttcaggc cctctttttt aacctcgttc ctgatttcat 3897661 caataaagtg ttcaggcaca tagacaattc ccgtcagaga agaagtcgtg acgacggctt 3897721 ctctccccac atgaagaatg cttagttccg cttgttgctc ttttgccaaa tgcactgcgg 3897781 catcaagcgc ttttgcactc atgtctgatc cgtcaatcgc tactaacatt ttgttaaaca 3897841 tgctcttccc gcctttcgga ctgtgggtgg ttcatctttc tcttttattg tccgcctgca 3897901 tttcgttatt gtcaattgaa gcgcatgagt tttcaaaaaa ttgtcagaga ctctctccgt 3897961 ttgtggcgat aacctgctga taccagttga agcttttttt cttgatgcgg ttaaatgttc 3898021 catttccttc attgtcccgg tctacataaa tgaagccgta gcgctttttc atttccgcag 3898081 tagatgcgct gacaaggtca attggccccc atgatgtgta tccgattaat tcaacgccgt 3898141 ccgcaatggc ttcgcgcgct tcaattaaat gatcacgcag atagttgatt ctgtaatcgt 3898201 cctgaatcgt gccgtcctct tcaaccttgt ctacagcgcc aaggccgttt tcaacgatga 3898261 acagcggctt ctggtaacgg tcgtataagg tgttgagcgt gatgcgcaag cctttcggat 3898321 caatctgcca gccccattct gatgatttga ggtaagggtt tttgactccg cccagcaggt 3898381 tgccccctga ttttgcaagc tcttccggat ctgtgctcgc cgccatcgac atgtagtagc 3898441 taaatccaat ataatccacc gtatgttctt tcaagagctc ttcatcgcct tcagccattt 3898501 caatttcaat attgttttct gccagatagc gtttcatata tcccgggtat gcgcctcttg 3898561 cctgaacatc tgagaagaaa agtgttttgc gctcattctc cattgccgcg aagacatcct 3898621 ccggcttaga agtcatcgga taggttgtcg ttgccgctat catacagccg attttcgaat 3898681 caggaatgat gtcgtgaccc gctttgacag caagagcact ggccacaaat tggtggtgtg 3898741 ccgcctggta catcgcgttt aatttgtttt ctccttcttc aaaaacaaga ccgcctccgg 3898801 taaatggcgc atggagcact acgttaattt cattaaacgt catccaatac ttcactttgt 3898861 gttgatagcg tttgaaaacc gttttggcat agcgttcata aaactctatg actttgcgat 3898921 tcttccagcc gccataattt ttcactaaac cgagcggcat ctcataatga gagatggtta 3898981 cgacaggctc aatatgatgc tttaacagct catcaaacag atcatcataa aatctgaggc 3899041 cttcttcatt gggctcctct tcatcgccat tcggaaaaat tctcgtccac gcaatcgatg 3899101 tgcggaacgc cttaaatccc atttctgcaa ataaggcgat atcctcttta taacgatgat 3899161 aaaagtcaat cccgttgtga tacagattca aggaagtcat tgattcatca aatggagaca 3899221 tgatcccgtt cggcgatacg tcagctgtcg aaagcccctt accaccctcg ttataagcac 3899281 cctccacttg gttggcagca actgcgccgc cccataaaaa tccttctgga aatcgttttt 3899341 catttgaact catattgatc accccattag ttttttcaag ataaagcaag cagcgcttct 3899401 tttggctgca ctttaccgat ctctttcacc ggcgaaaacg aatattggtc tgtgttggtc 3899461 acaatcaccg gggtaatgac gtcatatccc gcggctttga tttgctccag atcaaaggac 3899521 acgagcggat ctcccggtgc gaccttgtcg ccttctttga tgtgagccgt gaaccattgt 3899581 ccctccagct ttaccgtgtc caatccaatg tgtatgagta tttcagctcc ctgatcactc 3899641 gtaatgccaa ttgcgtgttt tgttttaaaa atggtggtaa cgcttccacg aacaggcgaa 3899701 acaacttctc cttcttcagg ctcaatggca aatccttttc ccatgacccc agcagaaaac 3899761 actccgtctt tgacttcact taaggctttc acttctccct taatcgggct gtgaatgatc 3899821 tctctgctgc cttcatgcac tgccggctgc tggctgccgt cagaaggcac atcctcgaat 3899881 ccaagcaaat acgcagctgc tgttcccgcc gcaaacgcaa tcacaaggcc gatcatcgcg 3899941 taaataaacg ttgggccgat aaagacaggg atgctcggca gacctgcatt ccccccgacg 3900001 atataggaag caacacccgt catgccgtaa aacgcgccac cggctgcacc gccaatcaaa 3900061 gcggccgcaa acggcttttt caatcgcata ttcacgccgt acatcgcagg ttctgtgatc 3900121 cccatcagcg ccgtgatgct tgtggtaagc gcgagtgatt taaatttttt gtttctagag 3900181 cgaaggaaga cggcaaatga tgctcccgcc tgccccatat tcgccaaaaa catagccggc 3900241 agtaaataat cgtggccgtt ttgagcgatg ttgttgatca tgatcggcac aaaggcatag 3900301 tgcatgcccg tcataatgat taaagagaat gtacccgcca gcaaaatcat tgccacaagc 3900361 cctgcatgat caaacaaata attgacccca gaagacaagt attctcctaa aatagcgcca 3900421 agcggaccga ctgtaatcaa tgtcagcggc acgacaatca atagcgtgaa tgtcggaacc 3900481 acaatcaatt tgagagatgc gtgtgtaaaa cggtcaatcc atttttccac gtatgaagca 3900541 atccaaatcg acagcaaaat cgggatgacc gttgacgaat aagtggcagc ggttacagga 3900601 agcccgataa aggaaatcgg tttccccgca ccgagcaggg ctgtcaaatc cggatgcagg 3900661 atcgccgccg caatggcagc cgctacgtac ggattgcttc cgaattttct cgccgcactc 3900721 atcgctagca ggagcggcag gaagtagaac gcaccgtcac cgacagccgt caaaatgaca 3900781 tgaacctggc tcttctccgc catccagcca aacgtgactg ccagcgccac aagtcctttg 3900841 atcatccccg ctcccgcaat cgcaggcaga ataggggtaa acaccccaga aatcacatca 3900901 aagaccgcac tcagcacatt ctttttctga gaggatgaac cagcgctctt ttcatcactg 3900961 agattgctgt gccgcacaat cgcctgatac accttcggca catcgtttcc gataatgatt 3901021 tgaaactgct cgccgctgat attggtgccc atcactccag gcagctgctc cagctgactg 3901081 cgatccgcct tcgcgttgtc atgaagatta aaacgcagcc tcgtcatgca gtggatcacg 3901141 cgctgaacgt tttcttcacc gcctacgagt tgtaatatgt ccttcgataa tttatcataa 3901201 tccatgtgta tacctccttt ttatgggggg actgctggat gaaaggtggc cgcctttcac 3901261 cagctttttt tgtatcaaat gctgcatcac ctcctaaaag agaataaaaa aacctaaatg 3901321 acacagattg cgagagtctc ctcctgcacc tgcaccattt aggttttgcc tgctttcgca 3901381 gtaacaatcc tgacgggtcg ttttatttgt ttgtaggtat actttagcac tagattcgtg 3901441 agatgtcaac gctttcattt ttggtgttga ctatcgtttc tagaacaaaa gtaatcataa 3901501 agatttgaac ttagtattaa cttcaataaa aaattattgt aattaaaaac cttgaaaggc 3901561 attttttcca atcaaggtta tgaatcgtta ccgtttaaat ttttttaaag acttctttat 3901621 ctgtactatt acattcttta gccaatctat tggttctaaa ttaaacgcag gaagatacac 3901681 gccatctgcg caagattgaa tgtaatcgtt tttcttattg tctgaatgct cactttcaat 3901741 aaaatccgtt aaaaagacaa tagcatcctc caaatattcc ttactttcct ctattaataa 3901801 ctcttgtata gcgtcatcag gagtttcaat atcttgatgg aatgttccag ctaaaaactg 3901861 aaaaacaggg tccttctgtt tattgatcaa taacatgtca tcttgctcct ttaagggaga 3901921 ggtaacggga taatgttaaa atcattcatc atctaataaa tcaagataat actgatcatt 3901981 ctcttctatt tttcttaaga actcggtaag agaagttgca atttgaatat cataatagta 3902041 aatcggattt ttattattat catttaattc aattgacatt aatgccgatt cactaccttc 3902101 aaaaaatatt aatttatcat tctcaaactc atcatatatt tctatgtcag gataaaattc 3902161 aaagtcattt atcctcaatc gaaagtctct tacagaatat ggatccaaaa tgcgattagt 3902221 attaaactct gatcctttaa taaacccata gccaacttct aaataaaaat tcactaattc 3902281 actaggtaat tttaagttta aatttttttc aacctcttca atctcacttt gattcactgg 3902341 ataaaaatca ttttctttgt ttgattttat aaaattataa ctcatttttt tttgcctcct 3902401 ttaaataatt catttgctgg tgagcctgta ccatgaatcc cagcttgatg ctcgttagga 3902461 aattttgctg gatgcatatt ccaccattca tgttctccgc caaaagtatt ttcaattata 3902521 tggtgagcat catacttatc cccttttttt ctaataattt tacctgtttt ttcagataca 3902581 acattttcct tataaacagg ccatttttgt ccagtgtttt cttcccattc ttttataact 3902641 ttatttttta ctttatcaaa tttagtcctg tgttttgcag tctctattgg tgacattttt 3902701 ttatattctt tatttcttaa tgcttccttt aatttatcta tttgattttt aggtaattct 3902761 ctacctgtgc gttgttctat atctctagca tactttttta ttaaatcaga attaatttta 3902821 ttagcagatc cacttacatc attcgcaatt ttccctttat ccttagcaac gtttttaact 3902881 tccgaagcct tcttagcctt tttcccatta ttaataagtt tattaatatc tattaacttt 3902941 tctaacttag ctattttggc aaatggtact gagtttatgg aggcaacaac acggtctttc 3903001 cctgtgactt tttcgcctga taccggatct ctgcccgtgg ctgctttaaa tagatcatac 3903061 acgccggtaa gttctacagc cgtctctaaa attttcacat atccattctc atccacttta 3903121 atgtccgaaa gcgagacgac aggttcaagc ttcatgtcat taccagatat gtatacattg 3903181 taaagtgtat cattataaac gacttgctta acctctgcat ttgagaaatc agtttttata 3903241 tgttctctat gttcactcgt attatacact ttaccattga taacgatgat atttttactt 3903301 acctttttag aatcacccgt tttgacaact gaatccactt tagacttttc attctcggct 3903361 aatttcttca gcatcatctc catcggtgaa tcatccgcct gcttcatttg cgggttaatc 3903421 gcgccgaaga tttggttgat gttttcttct tcctgtgatt tcaggatgga gccgcttttg 3903481 tagcctgtga tttcaatttt cgggccggtg tacatggttt cgagctgatc aatgtatttt 3903541 ttcatcgttt gaaaatctga ttttgcggct tctagtgctt gggtttgctg gccgtcaaat 3903601 tgaaagagct tattcagggt gtctgaaatc agccgctcag cctgttctgt ttccatccga 3903661 aaaaaggaat cattgactgt cggcaggctg acgatgtgat ctatggctga tgtctggcga 3903721 ttgactgcgt cagtgagctg ctctgtcact tctcgtgcat gcttgacccc atgtctcgca 3903781 tcgtgtgaga gaaaagcctc tgcgatcatg ccgtgggagt tagattctac agaggaaatc 3903841 gcatgctgtg tttgtttcag cacttttttg tattcgtcga taaatatgcc aaagaaaagg 3903901 agaaaaggct tgtggcactc ctcgtaaaag gtccggatgg catctccgcc ttttcctttc 3903961 agcgcatcct tcatgcctgc cagatgctca acgctttttt ccagcttctc cagctgttgt 3904021 ttttgcttgt ccagtttctc aatcgtatgc tgaatgccct cgtgaagagc gtggacatct 3904081 aatgttttca atcccttgtc ctcccgcgct ttatttcatg gaagatgata tgttttcgtc 3904141 cgtttccttc atggcgttta ccgcgctttc cgtttgtgcg atatgcttgg ccagaacaga 3904201 cgcatatgct tcagtgagct ctttgatgtc cttatttaat tgctcgatgg acttcacaac 3904261 attcaaatgg tttctgcctg agagatgacc gggcaatgag gacttgagtt cagctgaatt 3904321 cttgagctga gaaagccctt gcttcactgt gtcatacacc attttaattt cctgtgccat 3904381 ttgtgctcac ctcacttttt atgtttttcc ttctctattt catgctctat cctcgtgatt 3904441 tggcgtctta tagaatacac atcgccctct aatgagtgga tttttccttc tatgctttcg 3904501 atgattccgc tgacttgatc gcttttgatt tgctgatatg ctttgttcat tccttcacga 3904561 atatcttcaa accgctcagc atgtgttcct ctccatgcct cccggttaag atgaggccgg 3904621 tgaatgagat gctgggcctc agagaaatcg tgtttgattt gcctaatttc gtgcagcact 3904681 cgttttaatt gatggatctg ttcctgcttt tcatgtaagt cggcttttac cgaatgtaac 3904741 aacatttcac tatgcatgcc gcaacacctc gtgtttctat caaactgtgt aaattcttta 3904801 caatacagac tattttcata ttacatgatg ggtcatattg gataaatagg taaaaaggat 3904861 tgtcttgaga ggtatagaac tggttctaaa ttgctaaaaa tacgatctca tcaccctatg 3904921 aaaggagaaa acaatcatag tagggacttt ttatttaagc ctttaatctc tcctccagtt 3904981 ctaatttttc ctcccactta actgtttctt atagtcaata aagctcataa aaaaacacct 3905041 tccctcgaag gcgcttctcc atcttattta gatccccata cagcctcacc gctggtattc 3905101 agcacactaa acgtcatgac gttcttctct ctcaccgaat cccactggcg taaaaatacc 3905161 ccgttatact tcttgcctgc taacgtgatg tcggcggtgt tttttccggt tttcctccat 3905221 gttccggtca tttccccgga aatggtgtgg tttttgttga gctggatgtt gatggtttgt 3905281 ttgatgtcgg ctgagatgtc ttttccgtgc tggataagtt tgtatgttcc tgtgatgtct 3905341 ttttgtttta cttctttcaa tgtttcgccc gcataacgat atggtgctgc taccggccag 3905401 ccgtctttgt tcatgaacaa ttggtggact ctgacttcgt gttcttcacc cctgcccggg 3905461 aagcgggtgt ggaagattaa ataggaacgc ccggtttttt catcatagta tgcggagttg 3905521 tggcctggtg agacgtaccc ggtgcctttt tcattttctg tttcaaaagt gtagctgccc 3905581 atgagtttga cgccgtatgg ttcgatggaa cggtcgtcga agaatgtgcc tcccttgccg 3905641 cggacgtcga gcattggatt gccttctgca tcatagtaag ggccgtccgg tttcttggag 3905701 cgggccacac ggatgttgta gccgcctgtt gcatcgagac cgccatatga taggtataag 3905761 tagtagtatt gggtgtctgg attgtagaga acatacgggc cttcgattct gctgtggttg 3905821 ccgccgagca gttttttccc atatccctgt ccaggaagcg ggaagcccgt tttcggattc 3905881 atttcaagta tgaaaatgcc gcctgagtat gatccgtaca ccatccacag cttgccgtct 3905941 ttatcaaaga aggtatgcgg gtcgacgaca ttcggatgtt tggttgcatc atacggtgtt 3906001 ccatcgctgc ttgtgccttc cattcctgat ttcaaaaaga tgcctttgtt tttgtatggg 3906061 ccttcgatgt tgtcagcaac ggcaacaccc atggcggatc ttggcgaatc gccgcggcag 3906121 gcgttgtagt acatgtagta tttgccgtcc gccagctgcg tgacgtcagc cgcccaaaga 3906181 gtatcggatt gcgcccattc gaaggtttct tttaattctt catagacatt cgggataagt 3906241 gggttgtcat tgcttacgct ggtggtcagc tgctgccatt gcatgaggtc attcgattta 3906301 gctgaagcga gatgagatcc aaaaacataa aaagtgccgt ttgtttcaat gatggaaggg 3906361 tcatggacgc tgacttcttt aaatataggt ttttgtgcat agacggagtt tgggagggtg 3906421 aaggccatga taagagctgc aagaaaacat acacggaaca atcggttgaa catctaaaca 3906481 attcgcctct cttttttatt aaattttaaa cgcttacatt tctctatgaa gataccccgg 3906541 cctattaaaa cagccgaatg ttttcatatt catccagata ggtgatttct cacttcactt 3906601 acatagtcag actgatgtct gtctgttttg cgcagaactt gttgcttgca tatcctctcc 3906661 ttcatagttc aactcttttg ctgtttctcc ttcttgcatc acgtctgttt ttctttcgcg 3906721 tacatgtaat aactgctttg tcaggttttg catcaactgt gatacagcca tttcgttgtc 3906781 ggcgtttttt aagatgatgc ctgattgccc gtcaacacca gagtcattcg gctggctctt 3906841 tataaaacgc cttgcgaaaa atacgactta gtaaacgcat attgagagtt agacagcggc 3906901 gcttgcctcc ttgtctggat atcgtgtgca atcgctgaaa aaacctgttc tgctttctgc 3906961 gtcacgctat tacaatagca atctaacttg ttaaagacta taaaaaaacc ttttgacttc 3907021 tgctgctgaa ccaattaata taatactcag ttaatagtta tcagaatttt taggaattga 3907081 gtgattcata tgacactgca taaagagcgt cggatcggcc ggctgtctgt tctcctgctg 3907141 ctgaatgagg cggaagaaag tacgcaggtt gaggagctgg agcgagacgg atggaaggtc 3907201 tgtcttggca aggtaggatc aatggacgca cataaagtag tagccgcaat tgaaaccgct 3907261 tccaaaaaga gcggtgtcat tcaatctgag ggttatcggg agtcacatgc gctttatcat 3907321 gcgacgatgg aggctttgca tggcgtgacc agaggtgaaa tgctgctggg atcgctgctt 3907381 cggacggtgg gattgaggtt tgccgttttg aggggaaatc cttatgaaag tgaagcggaa 3907441 ggcgattgga tcgctgtctc gctttacgga acaatcgggg cgccgattaa aggtcttgag 3907501 catgaaacat tcggcgttgg aattaatcac atatgaaaca gcccatagat cttagacgat 3907561 agggggctat gcgtgaaaac agaagttcac agcatagctc ctttttgtat gggcgcttta 3907621 ccaaagtaaa gaaaaaggag ttgggcttat ggtgacttta gacggttctt cattgacaac 3907681 agccgacgtc gctcgtgtgc tgtttgattt tgaggaggca gcggcttctg aggaaagtat 3907741 ggagcgcgtg aaaaaaagca gagcagcagt ggaacggatt gtacgcgacg aaaagacaat 3907801 ctacggcatc aacaccggat ttggcaaatt cagcgatgtc ctgattcaga aagaagactc 3907861 ggcggcgctg cagctgaatt taatcctttc tcatgcctgc ggagtcggcg acccttttcc 3907921 tgagtgtgtt tccagggcaa tgctgctttt gcgcgccaat gcgctgttaa aaggcttttc 3907981 cggtgtacgc gctgagctga tcgagcagtt gcttgctttt ttaaataaac gcgtccatcc 3908041 tgtcatccct cagcaaggat cacttggcgc aagcggagat ctggcgccgc tttcccactt 3908101 ggcgcttgcg ctgatcggac aaggagaagt cttttttgag ggggaaagaa tgccggcaat 3908161 gacaggcttg aaaaaagcag gtattcaacc ggtaacgctg acatccaagg aagggcttgc 3908221 cttgattaac gggactcagg ccatgactgc aatgggggtg gtcgcctaca tcgaagctga 3908281 gaaactagcc tatcaaacag aacgaattgc cagcttaacg attgaggggt tgcagggaat 3908341 tatcgatgca tttgacgagg atattcactt agcccgcggc tatcaggagc agatcgatgt 3908401 cgcagaacga attcgctttt atctatctga cagcggcctg acaacctccc agggagaact 3908461 gcgggtacag gatgcctatt cattgcgctg tattccgcaa gtacacggtg cgacttggca 3908521 gacactagga tatgtcaaag aaaaattaga gattgaaatg aacgcagcta cagacaatcc 3908581 actcattttc aatgacggtg acaaagtgat ttccggcgga aactttcacg gacagccaat 3908641 cgcctttgcc atggattttc tgaaaatcgc aatatcagag cttgcgaata tcgcagagcg 3908701 taggatcgaa cgacttgtga atccgcagct gaatgacctg ccgccgttcc tgagccctca 3908761 tcccggtctg caatccggtg caatgatcat gcagtacgcc gcggcctcac tcgtttctga 3908821 aaataaaaca ctggcccatc ctgcaagtgt ggattccatt ccgtcatccg ccaaccaaga 3908881 ggaccatgtc agcatgggaa ccatcgccgc tcggcatgct tatcaggtga tcgcaaatac 3908941 aaggagagtc attgcgatcg aagccatttg cgcattgcag gctgttgaat acagaggcat 3909001 agaacatgca gcgtcctata cgaaacagct ttttcaagaa atgagaaaag tcgtgccgtc 3909061 cattcagcag gaccgtgttt tttcctatga cattgaacgc ttgactgact ggctgaagaa 3909121 agaatcttta atacctgatc atcagaataa agaactaagg gggatgaaca tatgactgat 3909181 gtaaaaaaat caatccgtgc caacagagga acagagcttg aatgcttagg atgggagcaa 3909241 gaggcagtgc ttcggatgct tcgaaacaac cttgatccag aagtcgccga gaagccggag 3909301 gacctcatcg tatatggcgg gattggcaaa gccgcacggg attgggacgc ttttcacgcc 3909361 attgagcatt ccttgaaaac attaaaaaat gatgaaacat tgctcgtgca atccggaaag 3909421 cccgttggca tgttccgtac acacccgcag gcccctcgcg tgctcctagc aaattctgtt 3909481 cttgttccga agtgggcaga ctgggagcat ttccacgaac ttgagaaaaa agggttaatg 3909541 atgtacggac agatgacggc tggcagctgg atttacattg gctcacaagg catattgcaa 3909601 ggaacctatg aaaccttcgc tgagctggcg cgacagcact tcgggggcag cttaaaagga 3909661 acgttgacgc tgacagcggg tctcggcgga atgggaggcg cccagccgct gtcagtcacg 3909721 atgaatgaag gcgtcgtgat tgccgtcgag gttgacgaga aacgcatcga caagcggatc 3909781 gaaacaaaat actgcgatcg aaaaacagca tcgattgagg aagccttagc ttgggctgaa 3909841 gaggcaaagc tggcaggaaa acctttgtcc attgcacttc tcggaaacgc agctgaggtg 3909901 catcacacac ttttgaaccg aggcgtcaaa attgatattg tgacagatca gacatctgcc 3909961 catgaccctt taatcggtta tgttcccgag ggctattccc ttgatgaagc tgaccgtttg 3910021 cgtcaagaca ctccagagct ttacgtgcgc cttgcgaagc aaagcatgaa aaaacatgtc 3910081 gaagccatgc tggcctttca gcaaaagggc tctattgtat ttgactacgg caacaatatc 3910141 cggcaagtcg caaaggatga agggctggag aatgccttcg attttccggg gtttgtccct 3910201 gcctacatcc gccccttatt ctgtgaagga aaagggccgt tccgctgggc ggcgctttcc 3910261 ggagatccgg cagatattta ccgtacggat gcgttattaa aagagctgtt cccgacaaat 3910321 aaagcccttc accgctggat tgatatggca caggaaaaag tcaccttcca aggcttgccg 3910381 tcccgtatct gctggcttgg atatggagaa cgaaaaaaga tgggcctcgc cattaacgag 3910441 ctggttagaa ccggggagct aaaagcgcct gtcgttattg ggagagatca tttggactgc 3910501 gggtctgtcg cctctccaaa ccgggaaaca gaagcgatga aggatggaag tgacgctgtc 3910561 ggtgattggg ctgtgctaaa tgcgcttgtc aacacggcgg cgggtgcaag ctgggtttcc 3910621 ttccaccatg gcggcggcgt cggaatgggc tattcccttc atgccggcat ggttgcagtg 3910681 gccgatggaa gtgagctggc tgacgagcgg ctcgcgcggg tcttaacgag cgacccagga 3910741 atgggcatta tccgtcatgc ggatgcgggt tatgaacgtg ccgttgaagt agcgaaggaa 3910801 caggacatta tcgtgccgat gcaaaaataa aggagtgatg acatgccaaa gcaaattgat 3910861 acgattctca tcaacatcgg tcagcttttg acgatggaaa gcagcggtcc gcgggcaggc 3910921 aaaagcatgc aggatcttca tgtgatcgaa gacgctgttg tcggcatcca tgaacagaaa 3910981 attgtgttcg ccggacaaaa aggggctgaa gccggttacg aggcagacga aatcattgac 3911041 tgttcgggac gccttgtaac gcctggcctc gttgatccgc acacccatct tgtatttggc 3911101 ggatctcgtg aaaaggagat gaaccttaag cttcagggca tttcatattt ggatattctg 3911161 gcgcagggcg gcgggattct gtctacagtc aaggatacca gggcggcttc agaagaagag 3911221 ctgctgcaaa aagcccattt tcatctgcaa agaatgctgt cctacggcac aaccacagca 3911281 gaagtgaaaa gcggctacgg cttggaaaaa gagacagagc tcaaacagtt gcgtgtcgca 3911341 aagaaactgc atgaaagcca gcctgttgac cttgtttcca catttatggg agcccatgcg 3911401 attcctcccg aatatcaaaa cgatccagat gattttctgg atcaaatgct ttcccttttg 3911461 ccggaaatca aagagcagga gctcgccagc tttgctgata tttttacaga aacaggcgtt 3911521 tttacagtca gccaatcccg ccgttattta caaaaagcag ctgaggcagg cttcggatta 3911581 aaaatacacg cagatgaaat cgatccgctt ggaggtgctg aattagcagg taagctaaag 3911641 gccgtctcag ccgaccattt ggtaggtaca tcggacgaag gcataaagaa attggctgag 3911701 gcaggaacga tcgccgtcct cttgccgggc acgacatttt atcttggcaa aagcacatac 3911761 gccagggcaa gagctatgat tgatgaaggt gtatgtgtca gcttggcaac ggattttaat 3911821 cctggcagct cgccgactga aaatatccag ctgattatgt ccattgccgc gcttcatctg 3911881 aaaatgactg cagaagaaat atggcacgcg gtcacagtca atgccgcata tgccatagga 3911941 aaaggagaag aagccggtca gctcaaagct ggccgctcag ctgatcttgt catttggcaa 3912001 gccccgaact atatgtatat tccgtatcac tacggggtca atcatgtaca tcaagtcatg 3912061 aaaaatggaa caattgttgt caacagggag ggagccattc ttggataagt acccttttct 3912121 cagagaggcc ggatcttcgt ttaaagaccg ggatgtcaca aaaatgagcg acctgatcgc 3912181 aacatgggac ggccaggaca ttaagggacc ggcgttgata ggtgtccccc tatcaaaatc 3912241 ctccatcagt cattcaggcg cttcctttgc acccggaaca atacgccagg ctctgaaaca 3912301 ttcatcagcc tattctgctg agcttggaga gcacgtcgta tcagagcttc tatatgacct 3912361 gggggatatc gatattcatg tcactgatat cgtaaagtca catcatcaca ttttccaaac 3912421 catgcacgct ctgctttcgg atcatccgga ttgggtgccg ctcatacttg ggggagataa 3912481 ctctatcagc tactccacaa taaaagcgat agcacaaaca aaaggaacga cagcggtgat 3912541 tcaatttgat gcccatcacg atgttcgcaa tacggaggac ggggggccga caaacggcac 3912601 ccccttccgc cgccttttgg atgaagagat cattgaaggt caacatttga tccagctggg 3912661 tatcagagaa ttcagcaaca gccaggccta tgaagcatat gcaaaaaaac ataacgtgaa 3912721 cattcacacg atggacatga tccgggaaaa aggactaatc ccaacgataa aagagatttt 3912781 gcctgttgtt caagataaaa cagatttcat ttttatatct gttgacatgg atgtcttaga 3912841 ccagtcccat gcacccggct gtccagcgat tggcccgggc ggcctctata cagacgaatt 3912901 gcttgaagca gtcaagtaca tcgcacaaca gcccaatgtt gccgggattg aaattgttga 3912961 agtcgaccct accctcgatt ttcgagatat gacaagcaga gctgcagctc atgttctgtt 3913021 acacgcatta aaaggaatga aactctcccc attcaagtga tcttctggca ggttgtattt 3913081 tgggtataag aaactcatct gcctaaggaa tggcagctaa aaggagggcg agacagtgaa 3913141 tcttcaggag aacagcagcc aacagctaaa acgcacaatg aaaagcaggc acctatttat 3913201 gatctcattg ggaggcgtca taggcacagg acttttcctc agtacgggct atacgctaca 3913261 tcaagccgga cccggcggta cgatactcgc ttatgtaatc ggcgggttga tgatgtacct 3913321 cgtcatgcaa tgtctcggcg aattgtcggt tgccatgccg gtgaccggct cttttcaaaa 3913381 atatgctaca acatttatcg gtccatctac cggttttatg gtcggcatca tgtactggat 3913441 caattgggtg gtgacggtag gctctgagtt taccgcatcc ggtattctca tgcagcgctg 3913501 gttccctgac agcagtgtat ggatgtggag tgcgattttt gcagcccttc tttttatatg 3913561 caacgcattt tcagttaagt tatttgcgga aactgaattt tggttttcca gcgtaaagat 3913621 tgtcaccatt attttattta tcattttagg aggagccgcc atgtttggcc tgatctcttt 3913681 aaacggaacg gcggatgctc ctatgttgtc aaacttcaca gatcatggcg ggttgtttcc 3913741 aaatggcttt ctcgccgttt ttatcgcgat gatatctgtg agcttcgcct tttccggtac 3913801 agagttaatc ggcgttacag caggagaatc agcaaatcct caaaaggata taccgcgatc 3913861 catccgtaat gtcgcatgga gaaccgtgat ttttttcatt ggcgctgtct tcatattatc 3913921 cgggttgatt tcatggaagg acgcaggcgt gattgaaagc ccgtttgtcg ccgtatttgc 3913981 ggagatcgga attccttacg ctgctgatat tatgaatttc gtaatattaa cagccttgct 3914041 gtctgtcgcc aactcaggct tatatgcttc gacccgtatg atgtggtctt tagcaaatga 3914101 aaacatgatc agctcccgtt ttaagaaagt gacatctaaa ggcattcctt taaatgcctt 3914161 aatgatcagt atggctgtat cttgtttatc tctcgtttcc agtatcgtgg cccctggaac 3914221 tgtctatgtg gtgatggtcg caattgctgg atttgcagga gtcgtggtct ggatgagcat 3914281 tgccttgtcc caactcttgt ttcgaaagag atttttgaaa aaaggggggg atgtaaaaga 3914341 tctgacattt cgcacgccgc tttatcctct tatgcctata gccgctctct tattatgttc 3914401 tgcttcttgt atcggtcttg cttttgatcc caatcaaaga atcgcacttt tctgcggagt 3914461 tccttgtatc atcctttgct atctcatcta ccatttcaaa agaaatgtta caaaagcgaa 3914521 aaaaatcagc caagaggaat atccagccga tcacatccta taattaaaaa agcacacccc 3914581 gctcagcatg ggatgtgctt tattttttat tctgtaatta acgtatgaat cagcttcggc 3914641 gccttcgctt ccgcggcgat gcggatgttg tcatagactt ttgcgatgac ttcatcgacg 3914701 ttttctcggt tagcgtaaag cgttacgagc ggttcccctt tttctacttt gtcgccgacc 3914761 tttttgcgga gcatgatgcc gacggctaaa tcgatttcgt cttcttttgt ggcgcggccg 3914821 gcacctaaca gcatcgccgc gacgccgatt tcgtccgcga cgatttcaga gacgacaccc 3914881 gcttctttgg caggcacatc aatttgatat gcggcttgcg gaagcttaga cggatcgtca 3914941 acaattgagc tgtcgccgcc ttggtttttc aggaaatcct tgaatttctc aagtgctttg 3915001 ccgtttttca tgacttcttc cagcttcgct ctcgcttcgt ccaatgtatc ggcttttttc 3915061 gcaagcacaa ccatctggct gccgagcgtt aagacaagct catgaagatc ctcaggcccc 3915121 tcgcctttga gcgtgtcgat cgcttctttg acttcaagcg catttccgat cgcaaagccg 3915181 agtggctggg acatgtctga aatgacagcc attgtttgac ggccgacgtt atttccgatg 3915241 cgtaccatcg ctttggcaag ttcagctgcg tcttcttctg ttttcatgaa ggcgcccgct 3915301 cccgttttta cgtcaagcac gatggcgtcc gccccggcag cgattttttt gctcataatc 3915361 gagcttgcaa tgagcggaat ggaattgacc gttcccgtta catcacgaag cgcgtacagt 3915421 tttttatcag ccggcgttaa attgccgctt tggccgatga ccgcaacctt gtcgcggttc 3915481 acaagtttaa taaattcatc cttcgtcagt tccacgtgga agcccatgat tgcctctaac 3915541 ttatcaatcg tgccgcccgt atggccgagg ccgcggccgg acatcttagc aaccggcaca 3915601 tcaagagccg caacaagcgg agcgagaacg agcgttgtcg tgtcgccgac gccgccggta 3915661 gagtgtttat ccactttaat tccttcaatg gcagaaagat caatcgtttc accggagttc 3915721 accatagcca tcgtcaagtc cgcgcgttca cggtcactca tatcctggaa gaaaatcgcc 3915781 atagcaagcg cgcttgcctg ataatcagga atgcttccat ctgtatagcc gttcacaaaa 3915841 aattgaattt cttcagtggt gagttctttt ccgttttgtt ttttgatgat gatatctacc 3915901 attctcatgt ttggtcaccg atccttttcg attaagttca gtaaatcaag cccacaattg 3915961 ctgctgataa aaagctgaca agcgtagcac cgtataataa tttcaagccg aaacgagcga 3916021 cgacatttcc ttgcttttca ttcagtcctt ttacggcacc ggcaatgatt ccgattgagg 3916081 agaagttcgc aaatgacaca aggaataccg atacgatcgc tgttgtacgg ccgctgaaat 3916141 ggaaaccgtt ttgcgtaagc gacgtcatgg cgacaaattc attcgatacc atttttgttg 3916201 ccataatgct tcccgcatta acagcttcat tccatgggat accgacaaga aaagcgaatg 3916261 gagcaaacac atatccaaga atgccttgga acgaaatacc gaatactgca ttaaaaatgc 3916321 cattgatcaa tgcaataatc gcgacaaatc caatcagcat cgcagcgacg acaaccgcta 3916381 ctttgaaacc gtcaagaatg tattctccga gcacttcgaa gaaggattgt ttttcttctt 3916441 cctcaacacg aagcatatcc tcttcttttg caacctcgta cggattgata atagaagcga 3916501 taatgaaacc gccaaataag ttcaaaacaa gcgctgttac aacatattcc ggtttcagca 3916561 ttgtcatata cgcaccgaca atcgacattg atacagttga catcgcagat gcgcaaagcg 3916621 tgtacaagcg ctgctgattt aaaagaccga gttctttctt caaggagata aatacttctg 3916681 actgccctaa aatcgcagaa gccactgcgt tatacgattc caatcttccc ataccgttta 3916741 ccttgctgag ggcaaggccg atatatctaa tgataaacgg gaggactttc cacttttgca 3916801 gaatcccgat cagagcggaa ataaacacga ttggcaagag aacattcata aagaatgtcg 3916861 tttggtccgc attcaccaag ccgccaaaca caaagttaat tccctctgcc gcgtattcaa 3916921 gcaggtaacc gaatcctttt gcaaatcctc ccacgaggaa attccctatt ccggtattga 3916981 ggagaatgta gccaagaata aattgcaaaa tgagcataac aacaattggg cggatcttaa 3917041 ttcttttttt gccgctgctc gcgatccacg cgaggcctaa aaacacgatt aaaccgataa 3917101 tcccaatcaa atacttcata tgtgtttctc ctttatttgt attcgcttac aattactgtt 3917161 tcctcagaaa acggaaagca gtctgccttc cgtcagctct taatagttgt ctccgcctga 3917221 tgcattttct ccttttacga tagaaacgcc tgcgctggcg ccaattcggc ttgctccggc 3917281 ctctaccatt gtgtctacat cttctttcgt tctgacgccg ccagatgctt tcacgccgat 3917341 atcaggccct actgttttgc gcattaaggc gatatcttcc ttcgttgcgc cgcctgtaga 3917401 aaagcctgtt gatgttttta cgaaatccgc tcccgcagac accgctaaac ggcatgcacg 3917461 ttctttttct tcatcagtca gaaggcacgt ttcgataatg actttgacaa gcgcttttcc 3917521 ggctacagct tccactacac cgcggatatc agcttccacc acatcgtctt ccttgtcttt 3917581 taaagcggca atattaatga ccatatccac ttcagtggcg ccttttgaaa tggcgtcttt 3917641 tgtttcgaac gcttttgttt cagttgtatt ggcaccgagc gggaagccga tgaccgtaca 3917701 aacgtcgact ccagttccct taagctcttt tgcagcaagc tccacccatg tcggattgac 3917761 acatactgaa gcaaatttgt atgttttcgc ttcttcaatt agttttagaa tgtccgcttt 3917821 ttgtgtatgc ggtttcaaag ctgtatgatc aattatgttg gctaatgaca tccttcgcac 3917881 acttcctttt ttgttaagat attttttagc ataaccgact tttgaacata tgtaaattgg 3917941 taattgaaat tttgttcaat gaaaggtttg aacgtgtcac aaatcattaa caagcgccct 3918001 cgcggtatgc tggtcaatga ttaaaacgtt ggcatatttt ccggttaatg ctccgtgaat 3918061 ggaagatact tttctgcttc cgccggcaac taaaatggag cgttccttca gtctaaggtc 3918121 ttgaagctca acaccgatgg tccggtcatt gatggcgctg ctgcaaatat tccctttcgc 3918181 atcaaaaaag cgtgaacaaa tatccccgac ggcctgtttt ttcagcaggg ctttctcttc 3918241 ttcgttaaaa tatccgagcc gaaacaacag cgcttcatca cggacagtcc cgaccgtaaa 3918301 gagagcgata ttcgcctgct tgcccatctc aatgatccgt tcaatatgac ggtctttctc 3918361 caccattcgc ttcacatccg cattatcaaa cacgacggga agcgggagat agcgcggcat 3918421 cgtttgaaaa gcctctgcaa acagctgaat cgtttcagcc gaatacgtgt ttacccggga 3918481 atggctgatg ccgcctttca gctggacgac ctcgacgcct tttacctgct tcggctgcat 3918541 gttttgcgcg atttgataca tggtggttcc ccagctgacg ccgacaatgt cgccgtcttt 3918601 taccgtttca tgcatatatt ctgcaccata gcggcttagg tcatgtgtaa ttcctgcata 3918661 atcgggtgtc ggggaaaaca caacatgcgc ctcaaggagc ccgtatttct cttcaagtat 3918721 ggaaccgagc gcatccaaat cctcaaaagg gtccatgacg cgaatctgga catacccttt 3918781 ttcctttgca tattgcagca gccgggaaac ggttggcctt gaaatgttga gctgctcagc 3918841 aatttgctgc tgactgtagt cagactgata gtaaagcctt gccgcttcta tgcttaattg 3918901 ctgtttttcc cgatccattc tgcacctccc tgtggatcag tcctgataaa actgcttttg 3918961 atttgctttt attatacagg ctggcgccgg ctttcatcca cctgatttct aagaaactga 3919021 aaaacgctct gggcgcggac ctgcccagag cttacttctc ccaagtcata tgctgataaa 3919081 tgcctttcat aatggcgtac attccatata ggatcaggcc taatgccaat atagacagaa 3919141 tcaatttgcc atgcggctgc tgcgcgagtt ctgcgagcgc gccgtcaaag cctcttgtgt 3919201 cgtcgggatc agcggtcatg gctgtcttga tgagaaaata gccgatagcc gagaaaataa 3919261 tggcccgggc gatattgcct gcgcgtcctg tgtttttcgt gatgcatatc atctgtttgt 3919321 tcatttttga tgtatcgaat tctttcataa aagcagcccg aacgcctttc ataaattgaa 3919381 caatcgcaaa tacgataaaa cccgcacccg taagccctgt gagccattgg ccgaacggct 3919441 gcgccaatac ataagcggac cacgtctgtt ctgaagtgcc gccgtcccct tggccaaaca 3919501 caaatcgcaa ggcattccaa gcgatggatg tgtaaacagc ggcactgaaa aagtttccta 3919561 ttctccgcga caggcctcgc ctgctgtttc cgtgcccctc cgtgtccttg atcgcgctta 3919621 acaccatcca gatcacatag ccgataaggc cgatgcctat aaaaaaaagc aatagtgacc 3919681 catacggcat gcgtgatagc gtttggagag ctccgctcga atctttggcg cggcctgccc 3919741 cggcagccgt cataaaagcc aaaaccccaa gcagaataaa aacgccgccg aatgcaaaat 3919801 aaccaagcct cccgaatcgt ttgatccaag gcttggtttc ctgttttatt tttgacatgt 3919861 accggtcttt caccgccatg tgtccaaccc tctttcacag aaatctttac tgtaacattc 3919921 ccgattgaac aaagttgaaa cagctcctgc ctcagctatg gctggctgag atacgttttt 3919981 gctgtttagc tgattgtgca ggtgtcatcc aagcagccgc tgcggcagct gtgactccgc 3920041 ctgctaattt cccaatgatc atggccgccg ccatttcttt tttcattcca gctacaaaac 3920101 cgagatggct gccgagtaca aaggcgccgc tgaccgcaaa cgcgacattg atgacctttc 3920161 ctctcggcgt catatccttt aatgaagcca gcattgggat atgatgcgcc aaagaggtca 3920221 ctaagcctgc tgttgctgtc tcatctaaat gaaggcattt ccccagagcc tgaagcggtt 3920281 ttttaaaggt ttttgtaata aatgccgtca tcgggaacgc ccctgccaga gcaatggcga 3920341 tggtccctgt cgtttgtatc cctgtctcga cattctccat tcccggaatc agcacaatgc 3920401 cggtcatcgt ttcaacagaa acagctgcaa gcccgataat cgcaaccata ctgaccgctt 3920461 tcccgaagag atgaaacaac tgaatcattc tgtcggtgta tcgccataac ccaaaagcga 3920521 tgacagcaga taacagactc gggatcagaa gatttttacc tatcatgccg atgtcaaagc 3920581 ctgcgcataa tccgccgatt aagcaaccga tcggcactgt gcacagcccg attaatatgc 3920641 ctttcgcaaa atacggatga tcctcttttt cgatgatgcc aagagcgacg ggaatcgtga 3920701 agacgattgc cggccccatc attgttccta aaaacaccca tgaaaacagc ccggcctgcg 3920761 gatctttcgc catttctcca gccagcgcat atcctcccat atcaatcgcc aaaatggtgt 3920821 tcgcaaagga agaaggatcc gcgccaatcg ctgtgtaaaa cggagcaaca atgggaatca 3920881 agattgctgc cagcacgggc gccagcgata caattccgat catggacagc gccagcggcc 3920941 ccatagcctt aaagccgtcc gcaaaccgct cgcctagccc ccatctgttt cccaaacaat 3921001 aatccgctgc tccccatagt aaaaaggcag ccaaaatgaa tacaaccgcg tcattcaccg 3921061 tcatggtttt ctcctttttc aaacgtatga ttggttttat catatcatct gaaatcaccg 3921121 aatagagttg atcttattca atatgagcta aaaattcttt tatatcggct ttttcaacgg 3921181 ctgttataat gcgtcgcgct ttttcttgcg ggaccgttaa tgtcaatttt tctattatgt 3921241 cttcttcaga cagctcattt cctggtgccc cttttgggca gtccacacgc gcttcgcaaa 3921301 tccggccgtc tgataaatag gcccggacaa tcgtgaaacg gccttttgga acggcatgag 3921361 gagccggctg aatagcattg tcatatacgc gctgaattcg ccccattgtc gtttgaaccc 3921421 cgtttgggat cggctggctg ctgaaatgtt caacggtcag gccgtgtcca tgcaaagcaa 3921481 gagcaatcac atattcaacg ctgaaacggc cttcctctcc agcttttgga gatctttccg 3921541 tcaatgcagc atctccgcct ggcggaaata tcacttcaat acgttcggta ttggcagcag 3921601 aaatggtttc ttcggagata agctgtcgta ccgcatctgc agcatggtgt gccgcggaac 3921661 aaaatggata gattttaaac catagacccg gctgcacaat tctccacggt gccccccaat 3921721 cgtttagcaa agtgtgttgt gctttctcaa cgtcaccgta cagactgaag aaaccagttt 3921781 ctccatcaag tgccgtgcgg gacccgccaa attctgattg ggccagctta acggccagca 3921841 agccagcctg agccgccaaa ccggcgtgca gcggtttcat ttctgttcca aattgcaccc 3921901 tcatcccagc agattgcgta gccgcaaaac caattgcttt ttccaactct tcctgagtca 3921961 gctcctcagc ataacctacg gcgcaggcag cagcgatggc accaagcgta cctgtattat 3922021 gccagccctt ctcatagtgg cggctgccaa ttgattctcc cagccgtgcc atcacttcaa 3922081 caccaacaac ataagcgcca agaagccgct cgtcatgtcc gcgagcggca gaagcaataa 3922141 gggccggtac gatgactgca ctggggtgtc ctcttacatc ggagtggaca tcatcaaaat 3922201 ccaatgcatg ggcgataaat ccattgagca tcgcggattg taatggcgcg gcctttttgc 3922261 cctgtccgat aacaggaaca aggggccggc ctccttcatc ctctatcaga cggaggagct 3922321 tttgaattcc tttatcttct cttcctgcga atgaagcggc agtaaaatca agtaatccct 3922381 tttttgcttc gtgaatcgcg tcaactgaat gctcaggttg tgacgttctc acagcctctg 3922441 caagacctgc tgtcagccct tgtttgctca tttgatggtc tccaatacaa taaccgccag 3922501 ctccgcaaag tattgagagg caaccgtaag ggcttcttca tccagtgtaa aggccggatg 3922561 atgccactcc tccgtcccgt tcgttcccat ccagacaaaa aatcccggaa tcttctcttg 3922621 atacagagcg aagtcttctc cgcccggaga ctgctcagcg tgaacggttt gatagccaag 3922681 ccgtgccgca gcttcggatg ccgcattcaa aaatgtgccg tcattctgaa cggaaggcaa 3922741 ataaggaaac cacttgaatt ctgcttgtgc cccatagccc gctgcaattc cttcagccac 3922801 tcgtctcata tgctcgggaa cagcctgcct cgcttctttt tgaaaggttc gaaccgtccc 3922861 ctccatttca gcttggtctg gaattacgtt ccacgaggtg cccgcctgta ctcttgtgat 3922921 actgacgact gcgttttgca gtgagctgat attgcggctg accacagatt gcagcccgct 3922981 gatgatttgt ccggctgcag cgattggatc aatactgtta tttgggatgc cggcgtgccc 3923041 gcctttccct ttgatgacga tctcaaatcg gtcaacactt gccatgagcg gaccttcctt 3923101 tacaccaatg gtcccgacag gcagatccgg cttattgtgc atgccgaaaa tcgcagaaac 3923161 gccattaagt acgccagctt ctagaacctt tcttgctcct gcggcaattt cttcggccgg 3923221 ctgaaagata aagcggactg tacctttcag ctcggccctt ctttgattca gcaacatcgc 3923281 tgtgccaata atagaagcag tatgaaaatc gtgtccgcac gcatgcattg tgccatcaac 3923341 cttagatgca aatggaagat tcgtctgttc ttggatcggg agcgcgtcaa tgtccgctcg 3923401 tattgctatc acggggccgt cttcccgtcc tttgatttct gcaatcacac cagtcttcaa 3923461 ttgagggaca tcaagtattt cgatttgctc ctcctcaagc caacggcgga tttttttcgt 3923521 cgtttcaacc tcttgaaatg acagttcagg atgttcatga agatcacgcc gcatattgat 3923581 taaacgggta tgaaacgctt tgtcggccat tgttcttctc cccttcttat ataagctctg 3923641 caggctctcc cacctgcttg ataaatcgtt tcgtccgttc gtttttcgga tggtcaaaca 3923701 gttcctctgg cgttccctgc tcgataatat ggccgtctgc cataaaaatc acttgatcag 3923761 caacctcttt tgcaaacgcc atttcgtgtg taacaatgat catcgttgtt tgtttttccg 3923821 caatggactt gatgacctga agcacccctg tgacgagctc agggtcaagc gctgacgttg 3923881 gttcatccag caaaatcgca tgcggattga ccgcaagcgc ccgcgcaatg ccgattcgct 3923941 gctgctggcc gccggacatt gtgattggat agctgtcagc cttatgctcc agaccgactt 3924001 gtttcagaat ctccattcca atacgtttcg cttcgtcgcg tggtttatgt tgagccacga 3924061 ttaaagcttc tgtaatgttt tgcagagccg ttttattttt aaacagattg tagttttgaa 3924121 agaccatggc cgtttgctgg cgaagccgat gtgcttcctt gcgtgtaaac ttttccgcat 3924181 tcagtttggc ttctccgatt tcaataaggc cttgatccgg acgctctaat agatttaagc 3924241 accggagaag cgttgatttt ccggaaccgg acggaccgat gattgccacc acttctccgc 3924301 gtttcacttc tagatcgatt ccgtcgagca cgacgagatc tttaaacgct ttgcgaatat 3924361 tttttactgt tatcaactga tttcacctct aagtccggta tggcttgctc atggcacgtt 3924421 caaacaagtc ctgcaaaatg ctgtagataa tggtaagaac ccaatagacg atcgcaaccg 3924481 ccaaatacgt ctcaaaatat ttgaggtttc ctgaagcgta catcttccct tgggcgaaca 3924541 tctccatgac ccctaatgta aaggccagtg acgtttcttt caggagcccg ataaatgtat 3924601 tgcccgttgc cggaatcgca tttcggatcg cttgcggcaa aataatccgt ctgtatgcct 3924661 gaaattttgt cataccgaca gacaggcacg cctccagctg cccgtcatca acagaattga 3924721 gggcggcccg gaagatttct gccaaataag ctgcgttttt taagcttaac ccgatgatgg 3924781 cagctgtgag agctgtcatt ttgctcatct ctggaaatag ctgcggcagc ccgtaataga 3924841 ttaagaacag ctgtacaagt gtcggcacgc ctcggaaaaa ggatatatac agctttgaca 3924901 gctgatgaag cactggaatt ttgttttttg taatgagtgc gagaataagt cctccgataa 3924961 tggcaaaaat catagctgct attgccataa acaaggtgat cggaagggcc tgaattaaag 3925021 tcgggaacgc tgatatcatg aattcccaat caatcgtgtt cattctggtg agtcaccgcc 3925081 gtttcttaat gcttctgttc tactgtgata tcttcattaa agtatttttc agagagtttt 3925141 ttcagtgttc cgtctttacg caattcatct agggccttat tgactttttt gcggagcttg 3925201 tcgtgcgcat cgtccttggc aaatgggaat gcaacctgtt cgtaaacaat cggatctcct 3925261 gcaagcttta atggcaaacc ggtcttcttg atttgcgcga tcaatacagt tcggctgttg 3925321 acataagcgt ctacacggcc gtacgcaaca tccttcagcg taccctcttg tgtttcgtac 3925381 gttttgatat tgattttttt atcaggatct ttgctttcaa ggtttttcgc gtggtttgaa 3925441 ccgagaacgg ctgcgactgt cttgcctttt aaatcgtcta ctgatttgat gtctgtattg 3925501 tcttttttga cgacaatctg tgttcccgca taagcgtatg gtttcgtaaa gttatacgtt 3925561 tccttacgtt cgtctgtcac agctacctgg ttggaaatgg tgtcaagctt gcctgtttga 3925621 agctctccca tcagcccgct gaattcaagc agcttccagt ccagtttcat gtcaattttc 3925681 ttagcgactg cttccatcac ttccacgtca aagcctgtca gctttccgtt ttctttataa 3925741 gcaaatgggt aactttgtcc tgtcgcaccg acatgaagca cattgtcatc ctctttactg 3925801 ctgctgtttc cattgccgca agctgagagc accgctaata atgcagcaac gaccagcact 3925861 gtccattttt tcatcttcat ttgattttcc cgccttttct atttttatag atcatgtcgc 3925921 aattgttttt tcatatagac tgtgatatgc ccttttccaa ggtcttgttc acctgagcgg 3925981 acatatcctt ttcgttcgta catctcaatc agccacggat gcttatccgc tgttccgagt 3926041 gagacaaacg gaacctttaa cgtatcgcga aggattgttt cctccagcca ttgaagcagc 3926101 tttgttccga ttcctttttt accggtgtcg gggtccacag caaaccacca gatatgcgga 3926161 acgccatacg gtcccggctg ttttccccaa ggcattctca aggtgatggt cgcgatgatc 3926221 cgcccgtctt cttccatgac gtagcaagca ttttcccgaa tatttttcag caccaaatcc 3926281 aaatccgcat gagcagcagc aaaacgaatg ccgagctttc gaatcggttc ataagcccgc 3926341 aatgtcagct cgagaagctg ttcggcatca cgttcaactg caaggcggta tcgtggcttc 3926401 atctagcgtt cctccttact ttgcatagcg gtttaccggc ttttccaaac cgaagtgctc 3926461 tcgtaatgtt gtgccttcat attcttttct gaacacgccg cgctcctgta aaatcggaac 3926521 cacttgatca acaaacactt caattccttc tggaagaagc ggaggcatga tgttaaaccc 3926581 gtcacacgct ttcgtatcca cccattcctg catcttgtcg gcgagctgct ccggcgtgcc 3926641 gacgaagata tggtggcctc tggagcctgc aacgtatttg taaagctctc gtatcgtcat 3926701 attgtcacgt tcagccatct cctgaacaag cttgaagcgg ctcttcaccg cattggaagc 3926761 ttcggcgtca agcttcggca gcggcccatc aagcggatat gccgacaaat caattccgcc 3926821 taagtaattt tggagaattt gcagaccgac agatgggata atcagatctt ggagctcctt 3926881 gtatttggct tgcgctgctt cttctgtatc ggcaatgatt gggaaaatac ccggcataat 3926941 ggcaattttt tctggatcac gtccgaattc cgcagcctgt tctttaatgg attgataaaa 3927001 ttcttgagct gattccaggt ggttttgtgc tgtgaagatc acttcggctg ttttggcagc 3927061 cagcgctttt ccgtctcctg atgatcctgc ctggataatg accggctggc cctgcggggt 3927121 tcttgaaacg tttagaggtc cgcgaaccga gaaatattct cctttgtggt tcagctcatg 3927181 cattttttct ttgtcaaaga attcacccgt ttctttatta cggataaagg cgtcctcttc 3927241 ccatgaatcc caaagcccct ttacaatctc gacaaattcc tctgcccgct gatagcgcaa 3927301 atggtgttca aggtgctttt caccgctgaa attcagcgct gttgattcaa tagatgaagt 3927361 gacgacgttc catccggcac ggccattgga cagatgatcc aatgacgcaa actgtctggc 3927421 aatatggaat ggctcgctgt atgtagtgga ggctgttgct gtcagtccga tttttgatgt 3927481 gacctgcgcc aaagcagaga gcagggtgaa tggctcaaac cttgttaata catttggatg 3927541 tgatttgctg tcaattgaaa ggctgtccgc taaaaacagc atatccagct tgcctcgctc 3927601 cgctgttttc gcaagctctt taaaataatc caaattcatg ctcgcatctg acggcgcgtc 3927661 cgggtgccgc caagacgcaa catgatggcc tgtacctgct aaaaataccc ctaatttgat 3927721 ttgtttcttt ttgcttgtca tggcgatact ccttttatca tgtttttagg ctgaataatc 3927781 cgaaaaataa actcctatat tcctagtcgt ttaatatgaa taaatcaaaa tgtacctttg 3927841 tcttggacgt ttgtcaatga gttaagatta attttttcta ttcaagcgaa aagacccttg 3927901 cgtgaccatg agggaacggc attgattcat tcaactagtg caacctctat atcggcaaga 3927961 aaactgagtc taatgaagca aagactcagt tttcttccaa taatttcata taagatttcg 3928021 ccatttcctt tgccttttct tcgcttttgc aaaccgccta tccattcaga cgccgtaacg 3928081 attgtataaa aaaacagctg actccagata ttcaaaccgg aatcagctga ttgatgtgaa 3928141 ttaattaagc tcatgaatac tctcttctgc tttagcggaa aacactttag gctccaaaca 3928201 gtcaaggtct tcatgaaata aatttacttt ttggatttgc cgattgtcat agtggtggaa 3928261 atagtagttt ccagtttcgt tgcacatcac ggaagtatat tgcgtataat gaatttcgtc 3928321 ttcttccgtt atcactgcgc cctttggtat cgtcatattt gccaaaattt gaaaagcggc 3928381 tgttacacct ttcgtttcat cggccgccgg ctctagatgt tctttcaaat aaacagctct 3928441 gacaaaccgg gaaggcggtg tataatcccc cggcagacca acagttccta agccttggcc 3928501 aaaagcagaa agggctaatc cgcccatctc tttgctctct aattgcttcg gtctgattcc 3928561 tgtatattgc tgcagattgg ttacatgcca tataaagtcg gggctgttcg tcatgacacc 3928621 aggttgatta tcatagactt tgaggccgtc tgctcttggt tctatcgtca ggtttcggcc 3928681 cgtccggtct gacaatatcc agtgaagcgg taaaactgta tccaatagat ctaatttttt 3928741 ctctacaatc gttaaagatc gaatcttttc ttttacgtct tccaaagact gacagactga 3928801 cagcacccat gtcacaaact catgcgggac aatgtgaacg gtatcttccc gtatcgtttt 3928861 ttcgtactcc gcatagcccg gaaaataaag cgccgcacaa gataaaccgc tttcattaat 3928921 gccgtcggca aataatatat ttccaagttt tctccccata ccgataaacg cgtactgtgt 3928981 ctgatgggcc cttccgtcag cttcactgtt ccagctgtaa cggcgcggat agagaatcac 3929041 ctctgtcccc agctgaaatg caaaatccat tgttcttgct aatacatgtt tacggtcagc 3929101 agtttccaat gtaagacttg tgcacatttg atcagtcccc ttttcaattc agattaatat 3929161 catacatatt gtgaacgaat tggttttatc agcataacga aagtcaaatc gattcgtcaa 3929221 agaattgaca ttacatcaaa taaaacgaaa aaatccagcc tttagaaggc tggatttttt 3929281 attatttagc caaaacaagc tcgtgaatcg catgtgcaac gccatgttca ttattggagc 3929341 gtgtttgaaa gtttgctgct tccaatactt ctgggatggc gtttgccatg gcaaccccgc 3929401 agcccgccca ttcgatcatt gtcaggtcgt tcccgttgtc gcctatgcac atgacttccg 3929461 cctgttcaat tccaagcagc tgagccagct ggcgtacagc atttcctttg ctggcttccg 3929521 agtgcagaat ttcataaaag aaaggcgcgc ttctgaccat tgtatatttt tctctcacgt 3929581 cttttggaat cgatgtaatg acgcggctta agttctccgg tttatcaata aacatcactt 3929641 tcgggatgag gatatctttt ggcacctcgt caatcttgcg gaaatgaagc ggcacctgtg 3929701 tcacatagga ttcgtatacg gtaaattcgc taatatcccg gttaggcgta tacaaattag 3929761 atgagtcaaa gaaatgcatc ggcgtcttca gctctaagct caggtcatat aatgaagtca 3929821 aatcatcata accgagagac agctctgaga ccacttcatt tgtatgcgta ttttgaacaa 3929881 gtgctccatt atacgcaata acatagtcgc cttcttcaat taaattcagt tcatctaaat 3929941 atctctgcac acccccgata ggccggccgg tgcaaagcac aattttgaca ccttccgctt 3930001 ttgccgcgtg aagggcgtcg cggacctcct ctgttacttc atgatgatca tttaaaagtg 3930061 ttccatccat atcaattgca attagtttgt acatcctgca tctccttcat gtcgttttca 3930121 ggctatagtc ccatcatatc gttttttctt tttgatattc aaccggaaga gatggttttc 3930181 tccggattct gtttagacgc cgcccttgtc ttcggatacg caagcgcggt ttccgctttc 3930241 tttctgcctt gacgccgttt tctgcttttt tctgtttcat cagcagaaag ccggcagcta 3930301 gaaaaggaat gccggttata ttcaagatgg caagcttcac acccgccgcg atgaaaaaga 3930361 acccccatga agatgatgga ttccgtctga tcatgacgta agccgccatt tccagaacga 3930421 tcaggatggc atgaagcact atgccataaa tcagcaatac aagggcaaaa aacaaaacat 3930481 aattcacgat tgcccctgag tacatcatag cgcgcatcat ttgtataaac gataaggact 3930541 gcatggagcc gctgatgaca ttagggttat agatcgtata gtcactaaat aaatgtttga 3930601 ctttgagaaa agcccataat ataaatatcc attgaatgat atgtaaaaca agccccgctg 3930661 ccaccagtct ttcagctttt tgatttctca tctttctcct ccctgccggt ctttgattcg 3930721 attcttgtca tcgtttttct ctgtccattt tgctcccata tcaatgtccc gttttctcct 3930781 cttttcagcg tgcttttgag cggataataa gggccgaggt actgaatctc gatagacccg 3930841 tcagtgcttt gggaaatcac cttgtatgcc ataaaaggca gctgtacctc tcctcttcct 3930901 tccatcactt ccgtttccac aacctcgtct tcggtaaatg tgactgttgc tgatttcaca 3930961 ccgtccgttg gcccgggggc acgcccctca tcccacgttc cgtaataaaa cggcgtctct 3931021 tctttttgct gctggcagcc cgataccatg atgcatacag caattaaaaa caaaatgcca 3931081 tatttgtttc tcaaggggat caccattctt tcctcctttt ttgggcgaat gccgtgccac 3931141 tgtgccaatg actacataag ttataaggaa ttcacccaca aggagactga tcacatgaac 3931201 ccttatcaat attacagccc tcagctgcct cagcaggaac cttactatag ccactatgag 3931261 tacaatcctt atccgcagca ggatgtatac gatccatacc aaatggacag acagccggca 3931321 ttggaaagaa gaatcgcagc acttgaacgg caaaatgaac agcagtcaag agaattaacc 3931381 cgtctgacaa acgaagaccg ccgtcaaaat cgggaaattg cacggattgc cgaacaggtc 3931441 aatcagttaa gccaggctgt tgaacgccat acacgccgcc taaatcggct caatcagcgc 3931501 ctccgtacag tagaaaaccg gctgaatatc ccatttactg caggggaagg cggtttctga 3931561 gcgaaacaaa gaaaaaaagc ggaatacgat tctcccatct cagggtttcg ttttccgcat 3931621 ttcttatatg ttaaaacgga acatttacat aaaaagggtt tgtacccagt atacaatctt 3931681 taccgttttc attcaaagat agaggggctg aggaaaataa ttgtagttcc tctttgacgg 3931741 aatttctttt cattcaagtt gcatgataat accgactcac gtcaatcgat acatggaggg 3931801 atcattcatg cataatacac aacacggctt gcagcagctg aaccaatgcc gccaaactgc 3931861 tcagcagctc attcagcaaa cacagcaaag cagccagcaa tatcgccaaa tgcttcatca 3931921 ggaacagcaa aacatccaaa tgctgcagca gattctaaac cacgaacaac aagctgcaca 3931981 taccattcag caagcactgc acgggcatga catggcgatt caaaagtgcc agcaggttgt 3932041 caacatgtgc aaccaaatgc aacaggaact tactggacaa tccagcgtca tgaatacgaa 3932101 tgtgtctaca cttccattcg gccaaaacac gacatttcag cagcaatcct accagcagta 3932161 acatataaaa agctcaacac aatgcgagtg ttgagctttt tttcttactg ttctttgcga 3932221 atatgtatat cctgaataga ctgtttcggt gcatgaaatc tgctctcggc ttcacttctt 3932281 gcctcggcaa aagcccgcgc ctccacatga tctttgtaga catccagctg aatcaaatac 3932341 agcgggcgca ctttaaatcc atgaataatg gttaccgccc ataacgggac cacaataaaa 3932401 acaccgggca gatcgggcaa aacaaaacca aacgcaaaaa tgaaaaaata aatgatgccg 3932461 tacatgatcc actttctatt tctaaccttg atgccaataa ataaaaaggc aaaaaaactg 3932521 gtaatggcaa aaggcatgaa aataaacagc atccaccagc tatgcagcca ttcccaagcg 3932581 gcacctcttt ttgtaattcc catatttttc tcctcctatt tacctataat aatcgattag 3932641 gcacaccgcg tcacccataa acgggaaaaa ctttctccct taaaaatagt gatagacgga 3932701 gaacaggttt cttgctatat tattaattga taatgataat cattactaat ctattgagat 3932761 acatagtggg agggttcttg atgaaaaaga acatattgct cgtgggcatg cttgtgctgc 3932821 ttctcatgtt tgtcagcgct tgcagcggca cggcttctaa agggagctca agcgattctg 3932881 cttccgaaaa aacagaaatg agaacataca aatcaccaaa agggaacgtc aacattcctg 3932941 cacatccgaa acgcatcgtc actgattttt atgccggtga attgctgtct gtcggggcca 3933001 atgtggtcgg ctcaggctca tggtcatttg ataatccgtt tttaaaatca aagctgaaaa 3933061 atgtgaagga tgttggtgat ccaataagcg ttgaaaaagt gatggagctt cagcctgact 3933121 taattgttgt catgaatgaa gagaatgttg ataaattaaa gaaaatcgct ccgactgttg 3933181 tcatacctta taacacagcg aaaaacgtag aagacacagt cagcatgttc ggagatatcg 3933241 ccggagcgaa agaccaagca aaatccttta tggctgactt taacaaaaaa gcggaagcag 3933301 ctaagaagaa aattgccggc gtcatcgaca aagatgcaac cttcggcatt tatgaaaaca 3933361 cagacaaggg cgaattctgg gtgttcaatg acaatggcgg acgcggcggc caagctgtat 3933421 acaatgcact tgggttaaaa gcgcctgaaa aaattgagca agatgtcatc aaaaaaggag 3933481 agatgaaaca gctctctcaa gaggttattc ctgagtatgc cgcagattat atgttcatta 3933541 cggattacaa cccgaaaggc gaaagcaaaa cactcgacaa gctggagaat tcctccattt 3933601 ggaaaaatct tgacgctgtt aaacataatc gcgtgtttat caatgacttt gactcgttct 3933661 acccgtacga cccgatttct gtcagcaaac aggtggatat catcaccgac atgctgatca 3933721 aacgggccga agaaaataaa aaataaaaaa acggcacagt catgacgctg tgccgttttt 3933781 tatgattcac tttaattttg actgtacgga gtccggcata tcttcaaact tgacttcttc 3933841 ccaagtctcg acatactttc ctttcgcctt caccttcaaa tacgcgttct tccgaagctc 3933901 tttgccggcg aaaaaggtca cttcttcttt tttcccggat gcattatatc cgtctaatgt 3933961 atattcagta ccgcccggac taagatgtct gccatctcga tcaatctgaa catagacatc 3934021 ttgctggtga ataaacggat taaatctgtc tgtaacatcg ttatgaaaaa agagaagccc 3934081 gcatattacg gcagcagccg ccaagacggc caggattgcc attgcttttt tcatctttgc 3934141 actcccctta cttgttcatt tttttcaaat agcttgaccg caccgcgagg aagaatagaa 3934201 gctgaaaaat gaaaaaccct ccgatggtga gactgagcgg ccccgctaca tcggaatatc 3934261 cttccacagc caatgttctc aaggcaaaca gtgtatgcat gacggcaatg acaaatggaa 3934321 agaagaaaag aatcgccaat tgtattgtca cgctttgcgc catttctcgc tcactcaggc 3934381 cgattttggc cagtgaacgg tagcgctccc ggtcttcatc taaatcagtg aacagcctga 3934441 aatataagaa acttgctgcc gcgacaaaga atacaattgc gataaacagg ccgataaata 3934501 gactcaggct cggcagctgc accgtatcat agtaagtccc cgcttttgaa gcaaaatcag 3934561 aatgcacgtc gatataattg ccgtaaatct cattttgcaa ggattggctg atctcaagac 3934621 tgtctttcca atgatcatag ctgtagccgt ataatgacgc tttatcaccg agtgatttca 3934681 gctgatcaaa ggtttgatca ttcaccgcga tgatagcatt caatgagatc agcggttttt 3934741 tgacttcttt taccgacagt ttttgatcag acagctcccc tttttggttc agcagcttca 3934801 gctgatccgg cgcttcgttt ttgaaattgc ggtcatacgt tcccgggaaa tagacagcct 3934861 cgtcttcttt caggccgttc actttgacat ggaagtattt tgccgcatcc gattcactga 3934921 tcatgtaaac agggggaaca gtttctcctt cctgatagcg aacataggaa acatctattt 3934981 tgtctttcgt atacgtaaaa ccgtgtgttt tcagttcatg gtcaatatct ttcaaatgag 3935041 tctgttcttt tggattgttg ctgtaagata aatactccat ttcataagcg gactcttccg 3935101 ctccgacggt cgatttgtac attgcgagca cgcctgtcgc agtaaacgca accgcggaaa 3935161 taatgctgac aataaagaac aggcgggcgt tgtcttttag acgatagaca aggtcagaaa 3935221 cccaaatgat gtttttcccg cgcagataaa aggttttcca cttcttcagc gcgcgcagaa 3935281 tccatatgct gctttggctg aaaaagaaat atgttccgat aacggtgagc agtaaaatga 3935341 taaacggttc ggccccgtgg acattgcctt taagaaccat gccgtacccg ccgcacagac 3935401 aggcgatgcc gaataaggac agaagcacgg acggcttagg ctccggttta accttgccag 3935461 tgccctttat taatttgata accgtatttg atctgacaaa aaggatcgta aactgcgata 3935521 aaaagaaaaa taagagcaga aatccgcagg ccgtaatacc gagcgctttc caaggcatat 3935581 acaaaggcag cgcgtccatt tctaaaatat aagcgccgac cgtaaagaac gtctttgaaa 3935641 aaatgaatcc tccgataata ccggctgcaa ttgacatgac gccgatgatc atattttccg 3935701 cagtaatgag ctttctcagc tgccccggcg tgatgccctg catgagcaga atgccgaatt 3935761 ctttatttct cgatttcaaa aatgcattaa ccgaatacag aacaaataag aaagaaaaaa 3935821 caaagatcat ccattccgcg gcggttaagc cttttttggc gatgttattc aggtagcctt 3935881 cctttaatgc cggatgaaac aggaacatcg caaaggtaaa gaaaatcaaa acggaaaagg 3935941 cgctgcttaa aaagaatgca agataggccc ttttgtttct cgtgacgttt ttataagcga 3936001 actgaagaaa ggtcatttgc gtttcccccc agcatagaca gcacatcgag aatttgttca 3936061 taaaatactt ggcggttttc cccgcggtaa atctcattaa acagttcgcc gtcttttata 3936121 aagatgacgc ggcggcagta gcttgccgaa accggatcgt gggtcaccat caaagccgtg 3936181 acatgatcat cccgattcag gctctgcaac gtttccatga cgtcttttgt cgctttggaa 3936241 tcaaggtttc cagttggttc atcggccaga atgagtgacg gcttatgaat gaccgctctt 3936301 gcgatggcgg cccgctggcg ctggcctccg gatacttcaa acgtccgctt gttaagcagg 3936361 ttttcgatac cgagctttgc cgcgatgccg tgcagttttt cttccattac agacggcgct 3936421 tctttttcaa gcgttaacgg cagcatgata ttttcaccga tcgtcagcgt atccagaagg 3936481 ttgaaatcct gaaacacaaa tccgagctgc ttgcggcgga aatgagcgag ctttgtccgc 3936541 ttcaggcgat gcgggttttc tccgttaatc aggatatcgc ctgaatctgg acggtcaatc 3936601 gttgaaatga tattcaaaag cgttgttttt ccggacccgg acggccccat caccgccgtg 3936661 aactcgcctt cttctattga aaatgaaatt tgctttaagg cctgatagga cacttgtcct 3936721 ttataggttt tatttatatg tttgacttca agcatattcg ccatgaaaat cctccttatg 3936781 gttttattct tgttgatctg ggctgctttc atgtagtgcc gggacgttca acataaaaat 3936841 ccccttgaca taaatccatg ttatcaaggg gaaacaaagc gggctatgtt gttttcttaa 3936901 cgcagcctta catttttgta agaaatgaaa atcgaactga tgtcccttca ccgggagacg 3936961 agctgatgtc caccgtatga ttgagcttat ctgtaatttc tttgacgaga tggaggccga 3937021 ttcccgtaga ttcttggaaa cgccgcccgt tttcacccgt gtaataaggg tcaaacaccc 3937081 gcttgatgtc ttgtgaggga atcccgacac cgtaatcttt gacttcaagc accgtcctgt 3937141 cttcatcgca gaagacattc agctcaagtc tgtcactctt gcccgctgaa tacttgaccg 3937201 catttgtgac cacttggcca atcgcaaatt tgagccattt ggcatcggtg taaatctgat 3937261 gatcatcgca aacgttcatt ttcggataaa cgcgatattg aataaaaaat cgtttatagc 3937321 tttgaataac tgattggaga agctcggaca gggaaaccgc ttcgatttta aaatcccgtt 3937381 caaacaggtc gagccttgaa gaataaagaa gcgtctccag cccgaattca atctgccgga 3937441 cttctttttt gatttgttca aaaacgggct catcctcttc ttgaatgatt aaattaatga 3937501 ccgacagcgg cgtctttact tggtgcaccc attgattcat atacgtcacc cgcgcgtcaa 3937561 gcttggcttc ggtctcatgg agcttctggt gctgcagccg gatcagctcc atctgctttt 3937621 catacagctc tgaacagaac actgaagaac cgagatacgg gatatccgtc ccttcctgcc 3937681 ccgagctgag ccaatgatac acgccgcggt ctttgtacca gcgataggca agatagcccg 3937741 ccaaaataag aagctgcacg cccaatatgt aaaacaagtg agaaaaagaa tgaagacccg 3937801 caaaccagta ataaaagaag acaaacagcc cttgaaggag aaaaagcaga atcagcactg 3937861 catgagaccg gagaaacagc ttcatgactg cgccctcagc tggtagcctt cgccccgcac 3937921 cgcttcaata gaaacaggcg cattcagctc ccgcagtttt tttctgagcc gcgtgatata 3937981 cacgttaagt gtattatcat cgatgaatat gtcggtgtcc cacgtctttt ccatgagacg 3938041 gtcccgactc gtcacctttt ctccccgctc aagcagcact tccaaaagct tgctttcttt 3938101 tttagaaagc tcactttttt catcctgaaa acgcagttca aaccgttcca caaagagctg 3938161 aacgccggca tattcaacca ctttctctcc ctgctttgcg gcgtactccc cgtacgccct 3938221 ccggatctgg cttttgattt tcgcaagcac aatatcataa gaaaacggtt tttcgatata 3938281 atcgtctccc ccattttcaa tcgccatcac ctgatccatt tccccgcttc tggcagaaat 3938341 aaagatgatc gggcttgtgg agtgctggcg gatctgccgg caccaataat atccgtcata 3938401 tgccggcaaa ttgatatcaa gcagcaccac atcgggcttt tcccgcaaaa agacatcaag 3938461 aacagctgta aaatccgcgg cgaccactgt ttgatatccg tatttttcaa ggtaattctg 3938521 caatagtccg cgaatgtctt cactgtcttc cacaatcatg attttattca aactgaacca 3938581 ctcccgtttc ttacactgct gccatcatca taatcgtttt gggcgtatgg acgcaacacc 3938641 gcacaaaaaa accgccatct cggcggtttc tggtctcttt agccgacctg ctgcttagct 3938701 gctttaccgg ctgatccgaa ctctctcatt ttgcttcgca ctgtctcttc cacggcttca 3938761 atgccgggtg tcaaatagcc gcgcggttcg tacagatcgc tgttttcctg aaacatgcgg 3938821 cgtgtttcgt ctgtccacgc taccatacat tccgtattga tattgatctt cgcgtggccg 3938881 agcgtgatgg cttttttgat ctgatcctgc ggaatcccgg atgccccgtg aagaacgagg 3938941 ggaatatcag tcatgcggga gatagcctcc atttccttaa atccgagatt cggctcaccc 3939001 tgatatttgc cgtgtacaga gccgagggcg gcggccagcg cgtcgatatt ggtttcttta 3939061 acgatccgct cacattccgt gatatccgca tagcggaccc cgccgaccag tccgtcttcc 3939121 attccgccga ccgtgccgac ttcggcttct actgacacgc cgtgttttgc ggcataatcg 3939181 gtgacttctt ttgtcatcgc gatattctcg tcaatcggct gatgggagcc gtcaatcatc 3939241 actgagctga atccggcatc aatggcctgt ctgcagcgtt ccgcactgct gccgtgatcg 3939301 agatgaagca cgaccggaac ggtaatcgcc atgtcctcta ttaacgcgcc gaccatggcg 3939361 gcaatcgttt taaatccgcc taaatagtcg accaggcgat cggaagccgc ggcgatgacc 3939421 ggtgattgct ccttttgcgc cgcctgcaaa atcgccttcg tccattgcag gccgttgata 3939481 ttaaactggc caattgcata ttgctcccgc tttgcatctt caagaagctc tttcatcgat 3939541 acaaaagcca tattcacccc tcctttatcc attacatgct gaagtatttt gatacgacat 3939601 ccactgttgt ttttttcgct gtttgaatgg cttcctcagc agtcagctta tagtattcag 3939661 gccggaagag ctcaaccgaa acaacatcag agaagccgat ttccttcagt gctgataagt 3939721 gggcatctaa gtcaattgcc ccttgtcccg gccatacacg atcctcatct gttaaaaagc 3939781 cgattgggaa atcttctgta tcatcaatat gatagatgaa gattttcttt ccgtccgcct 3939841 gctttaagct ctcaatattt gaacccattg catggaagtg aaaactgtca aggacaagcc 3939901 cgacattgtc acggttaact gtgtttacaa tctcatacgc ctgttcaaac gtattgaccg 3939961 tacattgcgg atggccgaca aactcaagcg cgatttttac gccgtacggc tccgcgatat 3940021 ctgacagctc agtcagcacg tctacactgc tctttttgat ctcttctttt acaatcttct 3940081 gctctgtcac aagcggaacg gccaccacat atttcacacc gagggttttg catgtttcca 3940141 tcatgccttt aaattcagtg atgatctcgt tgtgaccctt ttcatcacgg ttgttgaaga 3940201 aaacgagtgc gtttaaggca agcggtttga tgtggtgggt ttgaaaatat tccgcaaggt 3940261 catccaatga atgatctttt aagtactccg gcagcttatc catagtacgg atttcaatat 3940321 aatcatagcc atgcttttcg catagttcta aatccagttt aaggtttgag ttttccaatg 3940381 ttgtcgcttc attaaaacaa agtttcatgc cagactcccc catctgcgtt ttagatatga 3940441 agggagttcg gcaggaaggc tgtcgccata tcccgccgaa ctccatgctc agcttatgcc 3940501 agacctaatt cttctttcat tttcttaagc ataaatcggc ttgattcatc cgctctttca 3940561 tcgacccaag caaatacggc attcgtcgca attccgtcga acttcatctc tctcagtttt 3940621 ctgaaaatcg tatcaaaatc aacctcgcct tggccaatgt ccaaatgctg gtgaaccgtt 3940681 actttcgcgt caggcggatt gacgatgtag cgaaggccat gagccgcttt atgattatag 3940741 gtatctgcaa ataaaacatg tgtgaggcgg tcgccggctt cgtcaaacat ggtctcgatg 3940801 tcgcctttgc cgtcatcata gaagaacgta tgcgcagtcg agtagacaag attgatccaa 3940861 tccttgtcaa gcgcgcggat catatccatc gcacctttgt gcgtttcgat aaaatcatat 3940921 ggatgggctt gaagattgag tttaatgcct tctttttcaa agactggcag aagctcatcc 3940981 atggatttga taaatttttc ttcacttgtt aaaggatcat attttgaacc gctgaattcg 3941041 ctgttcatca aatccacttc aagttcaacc gcaatttcga ttgcccgttt ccagttgcgc 3941101 actgctgcct ggcggcggtc ttcatcgggt cccgcccagt ggtaaagagg aagaagcgat 3941161 gaaagcttaa cacctgtatc tcttaaaagg cgctttaatt gtttgatctt tgctgaatcg 3941221 actttcggat atttataaaa cgggcaaaaa tcctcgcgcg gcgataattc gatatattca 3941281 tagccgagct ctgccgtttt atagaccatt tcctctaaag ttaaatcatc acgatacatg 3941341 gatggatcca atgctaactt catattttca ctcctctgtt ttttagtttt gaactgttgt 3941401 aaaagattga tagaattccg gtttttcctt caattcaacc ttttcttttt gtccagattc 3941461 ctgggctttt acacacgcgt cagtcgtgac agcagcaata tagccgtccc atgccgtcgg 3941521 tccgctgacc tcgcctttct tttgaatcga atcaataaag tcttggattt ccacatcata 3941581 cgcagcgaca aagcgtctct gccaatccat caaaatatca gtgctgaatc tgccttcttt 3941641 tctcaagctg atgcttgatg gctcgggaag cttgatgatg ccgtcttctc cgacgatttc 3941701 acattgaatg tcatagccgt atttacagtt cacatagatt tcagcattga tgacgatacc 3941761 gccttttgtt tcaatcacga cgatttgcgg atcttttaaa tgtggaagcg cgttttttga 3941821 ttttttcgga tagatgactt gaacggactc gtagtcatca ttgacgagcc agtggagcac 3941881 gtcaatttca tgaacaagcg tgtcgactac agccatatcc gttgtatagt tatctcctac 3941941 agtcgggttg cggtgcgcgc agtgaatcat aagaggctcg ccgatgacat gattatcgag 3942001 cgcttctttc agctgtacgt aaccgctgtc ataacggcgc atgaagccga cttgaacaag 3942061 gcgtttgccc actttgattt cttcttcgac aatgcgcatg catccttcag ccgttgtcgc 3942121 gagcggtttt tcacagaaca catatttctg ggctttaatc gctttcagca cgcttgactc 3942181 atgcgcaggc ccccagcttg tcactaaaac agcgtctaca ttttcgtctg caagcaagct 3942241 gtcatcattc ggataaaccg tcgcgtttaa ttggtattgc tcaacgacct tttgtgcagc 3942301 ttcttgatta acatccgtta cagctacaat ttccgcgcct gacagcttgt tcgtgatacg 3942361 gttaatatgt tcttttccga ttgctccagt tccaattacg ccaatacgta aactcattga 3942421 cagccactcc ttctgttggt tacatgattt tgctttctgt tcctttcttt acttggctct 3942481 gaggagaccc gtagagttcc tcttgaattt gttcaagcga cttgccagac gtattcggcg 3942541 caaagagcag cccgatgatc atactggccg tcacacatcc gagaagaatt gcagccatcg 3942601 ttccaatgcc gaaattggtg ataatcattg ggacaaacag actccaaatc cctattgaaa 3942661 tacggacaag gaaaaacatc agtccttgtg cggaagcacg atattgcgta ggaaagattt 3942721 cgctggccca taactgatag ttcgcttgct gcccggctcc gttattgatg ccgatcacga 3942781 caataaacag gagcagaatc ggcaggcctt caactggcag cagaaacagt gtccacccga 3942841 tcaccgccat gaaagcggcg attccaaata cggtttttct atatttgtcg gcaaagggca 3942901 tgaagatcaa ggcgaccccc aatcctgtga agataaacag ccccatttgc aaaaggttgg 3942961 ccatgttggc agatacaccg ccgacctgct gataaatgta tggcataaag aagcccatga 3943021 ccccggcggc taggttccaa accaagtaca cacccatcaa aaacaggatg ctttttagat 3943081 acataggctt gagcaaatca aaatacgatg tcttattcaa tacagccggc ttctctgcct 3943141 gagcttcctc cggctgattt tttgtctgcc aggcgtctga ttccggaagc ctgattctca 3943201 ggatgtacgt aatcagcgca atcacaagca gatgggcaaa tacgatttta ttccccaaga 3943261 gtcccaagtc accggccagt acggagagga gcagtacaac gacagcgccc gcggcccaag 3943321 cgacttgtgc tacgccgcaa tgcctggccc gattcttctt tggcgcattt tccgcaataa 3943381 tggtccatga cgcggttatg tcagccccta ctgataaacc gataatgatg taaccgctta 3943441 acaacatggg gaaattaacc ccgaacaaaa ccaaacaaat ccctagtgca taaaccagca 3943501 tactattggt ataaacagcc ttccgtccga ctttatcagc cagaaacccg ccaagcagcg 3943561 cgccgacagc ggcagaaatc gcatttgcgc tcaacgcgcc gagcagcccg atttgcgtat 3943621 cggatagctt aaggtaactg acccataatg ataaaccggc ggagcctgcc acaattgaac 3943681 cggcatcaat atagttggcc aatgctgccg cgattgtccg tttattgaag gctgaatctc 3943741 cattggtatt gcccatatgt tcattcccca ttaagccaga tccaacaact gctgatcaat 3943801 atagtttctc gcaatcaatg catactccag cgggtttgca acatcggggt cttgttcagc 3943861 ttcaatgaca atccatccgg aataactgtg cttcaacagc agctgatata cttctctaaa 3943921 gtcaatgcag ccgtcaccgg gaaccgtaaa catgcctttt aaaaatgatt gccggaacga 3943981 ttgtccttcg agcctgcatt gttccatgac attcaggcgg gcatccttaa agtgcacatg 3944041 cttaatgcgg ccgatatgct tctcaagcat ccccatgtaa tcgccgtcag aaatatacgc 3944101 atggcctgta tcatagagga ggtgtacatg cgcagggtct gttcctgcca tcaggcggtc 3944161 cacttcttcc gctgtttgga caccagtgcc gagatgatga tgatagacaa gcttcaagcc 3944221 atgctgagcg gcaatttcgc caaggtgatt cagcccttcg caaagccgct cccattcatc 3944281 atccgtaaag tgcggcttct ctgtgaacac atttttctcc aagctttgca cgctgtacgt 3944341 ttgttcagag acaactgcga catccgcgtt tacttgctgc aaatactcac aatgcagggt 3944401 aaatgtcttt gccgcttcac caagtccgtc acgcaaaata aaactgctga accattttcc 3944461 tgcaatgcgt aagttccgaa gcttcagctc tttgttcagg atggcaggtt cggggaaaaa 3944521 gcccccgacc tccgtgcctt gaaaacgtgc gacaacgata tcacttaaca aatgctgaag 3944581 tgtatttccc gctccaattt caggcatgtc atcattccgc cacccaatgg gagcgattcc 3944641 ccacaggatt tcatttttgc ccatctatgg tgcctcccct ctaatactgc ttcgcagatt 3944701 ccagcttttt ctcttttgct tcgtatgctt tctgaacgct ttcttgttca gatacctctg 3944761 ccaccccgac atgccaccag ctgtcatagc cgtccgtcat tgttttaggc agcaccttca 3944821 tttcaattaa tgttgataca tcctgtttct tcgcatcctc taacgcagct tttaattctt 3944881 ctactgtgtt tgcacggtag gttttcgcgc cgtatccctc agcgactttc gcgtaatcga 3944941 cattcaggat ttggttgtca tctgtgcgga actcgcaata gtagctgccg ctgccgtgat 3945001 ccatttgcag gttgttgatg catccgaatc ctgagttgtc aaagagcagc acattgattt 3945061 tcttgttgta ctgaatcgcc gtgatcagtt cagaatgaag catcaggaag ctgccgtctc 3945121 cgacgattga atacacttct ctgtcagggt gggccagttt aagaccgagt gtcccggaca 3945181 cttcatagcc catgcaagaa tatccatact ccaggtgata cgtattcgga acattagaat 3945241 gccacagacg ctgcaaatct cctgggagtg agcctgctga acagatgatg acgctgtctt 3945301 caggaatcgt ctcgttgatt gtcagcaatg ccgttgtttg cggaagctcc gtattcaacg 3945361 cgtcagcata ttcattcagg acctcttgag aaaagtgatt tttgatttcc ggatcaaatg 3945421 cttcccgctt aaacgtcact ttgctgagac gctcgcgttc agctagccat tcgtccttca 3945481 gctcccggat cgttgtgccg aactcgctct catagccttc aagcaagccg tgcagtttgc 3945541 caagcgtcac tttcgcatcc gccaccactt ggaatgcatc aagtttatac gcctgcattc 3945601 ggctgacgtt aatgttcaaa aacttcgctt tatcaaaatc aaaagcggtc ttagaggatg 3945661 tcgcaaaatc tgtatacctt gtgccgatgc cgataatcaa atcagcttgg cgggccgctt 3945721 tgtttgccgc aagtgtacct gtgatgccca ttccgccaag gttgttcgca aaatctgcct 3945781 caacggtaga ctttcctgcc tgcgtttcaa ctaacggaat gttataggct tcagaaatgg 3945841 caaccaattc atcgcgcgca ccggaatatt ttgcgcctcc gccgacgaga atcacaggtt 3945901 ttttgctgga tttaatcagc tccgccgcac cttgaagctc gcgctcgctc ggctgcatgc 3945961 gatcaatata gtgaacccgt ttgacgaaga aactttcatc aaaatcgtat gcttcccctt 3946021 caacatcctg agaaatacaa atcgttgccg gacctgcttt tgccggatca gtcatgactt 3946081 caaacgcgcg cagcaaactg ctcatcagct gctcagggcg cgtaatgcgg tcccagtatc 3946141 tcgatacagg cttcaatgca tcgtttgtcg taatcgccgc actgtattct tgctccattt 3946201 gctgcagtac agggtctggc tgtcttgtcg caaatgtgtc tgccggaatc aagagaactg 3946261 ggatattatt tgccaatgca gtgccggctg ccgccaccaa gttagccgct ccaggtccga 3946321 cggatgtaga caccgcatat atttttcttc tcagcatttg cttgctgtac gccatggccg 3946381 catgcgccat tccttgttca tttttccctt gatagacttt caaatggcct gcatcctgct 3946441 caagcgcctg cccgatccct aatacgtttc catgaccgaa aatcgtgaag atcccttcga 3946501 caaaaggctc ttcctttcca tctacatgga tgtactgctg gtttaagaat ttaatcagcg 3946561 cctgcgcagt tgttaagcga attttcttac ccacaaacga tcccaccttt actcgatctt 3946621 tttcaattat gactgtgctt caataagctg ttcgatttct tccgcagtcg gcatcgcttc 3946681 tgacgaactg tgcttgctca ccacaatgga ggctgaagca ctgccgtatt tcaatgccgt 3946741 ttcaatgtct tttccgctga caaggccata gataaaggct gacgcatagg agtcaccggc 3946801 cccaaaggtt ttcagcactt ttgtcttgta cgcttgagcg cggaatacct cgccggattt 3946861 gctgtatgcg taagagcctt cgacgccgtg tttgatgaca acgaggtcgg ctgaatggcc 3946921 aaataaatga ttgacggatt cttcattgct tccgcctgtg cggttttcca tcacatcaaa 3946981 ttcatcgcgt gtgccgatga cgatatcaga ctgctcggca accaaagaat aataaacggc 3947041 tgtttcatct gatgactgcc acgtatatgg ccggtaatcc agttcgaata ccaccttaac 3947101 ctgatgcttt ttcgcgtatt gaacagcttt taacaccgct tcccgtgacg ggcttttggc 3947161 gagcgctgtc ccggagacaa gcagcatttt cgcatttgcg atatagtcct cacttacctc 3947221 tgaaggctca agataaagat ccgccacatc atcgcgatac attaagatgc tgcattcttc 3947281 agggctgagg atttctgtaa atgcaaggcc tgctttgtgt ccatcttgat caacaatcat 3947341 ctgtgtagta tccacgccgg tctttctcat ataggactct atgaatcttc catgctggtc 3947401 atccggaatt ttgccgatga agcccgcttt taagccaagc ttcgcgctgc cgatcgcgat 3947461 attcgcaggt gaaccgccga catatttcga aaatgtcatc gtttcttcca ttgggcggtt 3947521 gtattcgact gcgttcagat caatacatgc ccggccgatg gcaacaatat caaaagcctt 3947581 ctcttcattg aatgtatact tcatcgtaaa cagccactcc tcacttgtta gcgttctaaa 3947641 atccattcat gcgccgggtc gttataaaac ttccattttc gcgtcggccc tgccatgaca 3947701 tttaaatagt aggatgtgta tccgtccgga acgcctaccg ggtggtatcc cgcaggaacg 3947761 atgacaacgt tttcatttcc cacagtcatt gtctcgtcaa tagaacggtc atctgtgtat 3947821 acgcgctgaa acacaaagcc ctgtcccggg tctaactcat ggtagtacgt ttcttctaag 3947881 aaagattctt ccggcaagtt gtcttggtca tgtttgtgag gcgggtagct ggaccagttg 3947941 ccgctgtctg tatagacttc aactactaat agactgttag ctgaagggtc tgaatccgga 3948001 agaatgttat gaacagtacg tttgtttgaa aattgcccgc gatgctcaat tccgttgtct 3948061 tccgctttga tcagctttgt cggaagctgc ttttccgatg gagaatagca aagcgccact 3948121 cttgcgtcgc tgaccgctgt gatctcaaat gcacggtcat ttgaaatata gacgctgtct 3948181 gtcggttttc gttcaaatac gctttcgcgc gtgccgatat tctcaaaagt cgactcatga 3948241 tctgtcactg taattttccc cgttaccgcc acaatacaga tttcttgttt tttcaattct 3948301 tctgtatagc ttgaacctga tgcaagatct aacactttaa actctacata agtgagatca 3948361 gagttggatg tcgttacttc gtgcacgagt ttgaccccat tagacacttc atgcgactgc 3948421 ggcttacgca acaaataact catagagaag ccctcctctt tctattggca gaatgagtcc 3948481 gaacagcgca catggacgcc gttcggctgt tcgtcgttta gttgaaatca ggtgccggat 3948541 atcttgccgt caccactttt ttacgtgtat agaagtcgac gctgtctttt ccgttcgcat 3948601 gcagcgttcc aaagaatgaa gatttccagc ctgagaatgg gaagaacgcc attggagccg 3948661 gcacaccaag gttgatgcct agcattcccg catcaatgtt ttcacggaag tagcggattg 3948721 cgtttgagtt ggatgtgaac aagcaggcgc cgttcgcaaa ctcagactta ttggcgattt 3948781 caatcgcttc tttcaggttt ttcacacgga tgacagataa gaccggagcg aaaatttcat 3948841 ctttccagat cgtcatttct gttgtgacat tgtcaaagat cgtcgggccg acaaagtagc 3948901 cgtcgtcaga cacattttca cgtccgtcac atacgagtct ggcaccttct tcaagacctt 3948961 tttcgatata gctgagcgtg cgcttcttgt tgtcttcgcg aatcaccggt cctaagaaca 3949021 cgccgtcatc aaggccgtta ccgattttaa tgtccgccac tttttcctgc agcttcgcca 3949081 taaattcatc ggcgattcct tcttcaactg tcacaaccgc acaagccatg cagcgttcac 3949141 cggcagaacc gaaggcagct ccaacgatgt ttgtaaccgt gtcttcaaga ttcgcatcgt 3949201 tcaagacaat cgtatggttt ttcgcgccag tcagagattg aacgcgtttt aagttttcgc 3949261 ttcctttttt gtagacgtat tcgcctactg gcttggagcc tacaaatgaa atcgctttaa 3949321 tttcgggatg ctcgaggatg ccgttcacaa cgtcatgcgc accgtatacg acgttgaaca 3949381 cccctttcgg aaggcccgct ttttcaaaaa gctcaaccaa tttctctgtt aacagcggag 3949441 tccgctcaga tggctttaaa ataaatgtgt tgccgagcgc gatcgccatc gggaacatcc 3949501 agcaaggaac catcatcggg aagttgaatg gcgcgattcc gccgacaact ccgattgggt 3949561 aacggtagtt cgccgcttca acgtccgttg cgatggaagc aagtgagtca cccatcatca 3949621 gggaaggtgc tccagcggcg aactctacgt tttcaatccc gcgtcccact tcacctaaag 3949681 cttctttcgt gttttttccg ttttcaatgg taattagatg agcaagttct tctttatgct 3949741 gagacagcag ctgctggaag ttaaatagaa ttctggcgcg gcgaggaacc gccacctttg 3949801 accatgtttt aaatgcttca gccgctgttt gcgctgcgta atcaatatcc tcttttgtag 3949861 aaatcggcac ttggcatagc acttctttcg tcgccggatt gacgacatct tcatattgat 3949921 ctgttttgct ttcaacccat tcaccgttga tgtagttttt taattttctg atttctgcca 3949981 ttcttattgc ctccttcatt agtaaacaca tacacttgta tggatggttc cggatagatt 3950041 catatcaata tccacttttc agcaagccaa gaattaaacg ctttcaaaaa caccaaaaaa 3950101 ataaatggcg gatgcatatt tacatacaag caaccatttc atgcacaaca ggttactttt 3950161 tggtcatttc ttggttatat tctaatcgca taatacccat aagtcaatca taaacactac 3950221 attttttcat tatttttatt atattaatct tttaatcaag taagagaagt aagagaaggc 3950281 cgtccaatct tgcaaaagat atacaccgat gttatcattt ttaagcaact attgattaac 3950341 ttttggtttt tattatatat ttatgttacg taaagattca agaaggagtt ttttatatga 3950401 aactgatgcg gattcaggaa atggaggagt acattttatc gcatggcact gtttccttag 3950461 atgagctgtg ccaggtgttc aatgtctcca aaaacacagt cagacgtgat atcaacaagc 3950521 taacagaaaa gggtgcgatt gaaaaagtat acggcggcgt aacatctatt gaaaaaaccg 3950581 cattagttcc ttttgaaaat cgcaccattc agcaccagga tgaaaaaaca aaaatcgccc 3950641 attatgcttc ccgatttatt gaagatcacg atttggtctt cattgattca ggaacgacga 3950701 caaagtctat tcttgatacg cttgatccag ccaaaaatgt caccatctta accaacagtt 3950761 tagacattat caatgcggcg tcagctttga agaatatcaa cttaatcatt atcggaaaca 3950821 actataagag aaaaacccgc tcctttgtcg gcatggacga cccggctatg cttgataagt 3950881 acaatatcaa caaagccttt atgtccgcta ccggaacgac gctgactcac ggattgacca 3950941 attcggatct gctggagtat gaaattaaaa agaggatttc agaaaaagca aaagaagtgt 3951001 atctattggc tgaccattct aaattcggaa aatcaacgct tctgacgtat gcaccgtttg 3951061 acaggctgca ttgcattgtg acctctcagc cattagacga cgagtacacg cagtactgca 3951121 atgagcatca aatcggcatt catctggcct aacgtttaca atagtgttga gagtctatca 3951181 tccattttat tctaggaggc agatcatgaa aaaagcgaag ctcggaaaat cagacttgca 3951241 ggtattccct atcggattag gaacaaatgc tgtcggagga cataacctct acccgaacct 3951301 aaatgaagaa accggaaaag aattggtgcg cgaggcgatc cgtaatggcg tgacaatgtt 3951361 agacaccgct tacatttacg ggatcggccg ttccgaagaa ttaattggtg aagtgctgcg 3951421 tgaattcaac cgtgaagatg ttgtcatcgc gacaaaagcc gctcacagaa aacaaggcaa 3951481 tgactttgtc tttgataatt caccagattt tcttaaaaaa tcagttgatg aaagcctgaa 3951541 gcgcttgaat accgattata ttgatttgtt ctacattcac ttccctgacg aacatacgcc 3951601 taaggatgaa gccgttaacg cgctgaatga gatgaagaaa gccggaaaaa tccgttccat 3951661 cggtgtatcc aacttctctt tagagcaatt gaaagaagca aacaaagacg gtttggtaga 3951721 tgtattgcaa ggcgaataca acctgttaaa ccgtgaagcg gaaaaaacat tcttcccgta 3951781 tacgaaggag cataatattt catttatccc ttacttccct ctcgtatcag gtttattggc 3951841 aggaaagtat acagaagata caacgttccc agaaggcgac ctgcgaaacg aacaggaaca 3951901 cttcaagggt gagcgtttca aagaaaatat cagaaaggtc aacaagcttg cgccgattgc 3951961 cgaaaaacac aacgtggata tccctcacat cgtattggcc tggtatttag caagaccgga 3952021 aattgatatt ttaatcccag gagcaaaacg tgccgatcag ctgattgata acatcaaaac 3952081 agctgacgtg acgctttctc aagaggatat ttcatttatt gataagctgt tcgcataaga 3952141 agaaaacagc cttctccaat ggagaaggct gtttttttgt gcgataaatt cctaaataac 3952201 tgattttgaa gcaaaacctt acaaaatgag ccataaatcc gataaaataa aggtagttta 3952261 tctcagaaag aaagtgattg agaaagcaaa agtatgaaac gttcatatca tctagctcat 3952321 atgaaataaa gctgacccag cttcttttat ttgctggtca gaatagcgga ccgtttcgat 3952381 ggtctatgga ggaaacagaa tgaaacttaa atatgtaaaa gccttagttg cagtaaccgt 3952441 tgctttaggt gtactgctgc catcaacgat ttctcatgca aagagcttta gcggccgctc 3952501 atcatctagt tacagcagcc gaagttcaag ctcatcatac agcggaagct ataaatcaag 3952561 cccgaaatca agctacagct caggatcaag ctcttctagc aaaaaatcca agacgtctga 3952621 cgattcatca tcatcgattt cgcttaaaaa gaagccttcg gaaaaggcaa gttcatcaag 3952681 ctctaaaaaa tcgtcaggca ccttttccgg cgctacatca aaagtaaccg gaaagacata 3952741 cagcggaaaa acgtctaaag cctatgttgg cggacgttat gtttcagtca atcattacta 3952801 tcacgcaggt ttcgcgccat caggatggtt tggatattat agcggattta caatgggtat 3952861 gttcatgatc agcatgatgc acccatgggg ttacacctat catccagtcg gaggccccgg 3952921 ttatgtttct tatggcgctt cacccattgc ctggatcgtt gatatcatcg ctttgattat 3952981 tattttaatc attgtcatcg cattgattcg cgcatttaaa gcaccgaaga cgtacagaag 3953041 gagattttag gcaatgagat taatattaaa tgagcaagaa attgtagacg gaatttgcgt 3953101 gtatatttcc aatgaagaag atatctaccc tgaagacgtt gaagtaaaag aactatcgta 3953161 caacaagcgt acagggttct tcgctgaagc tacatttggc ctgcaccaca agcagcttat 3953221 gtcagatgac atttcagaag gcattattca gttcttagag gaataccaca acttcaatcc 3953281 ggacgttacc gtcgttgaat tgcaatttga taagaaaaaa ggcttctccg ccttggtttt 3953341 tgtcaacgaa gcagaagaat aaaaatgtct taatcaaacc ttactccgcg cgggtaaggt 3953401 ttttttaatg gtttctctga gcataaagtt atttcgtttt tcctaaactc agcggatctg 3953461 tgatcatctc ttttggctat aaagtttccg ttttttcaaa acaaatgttt caaatgagat 3953521 aggaaatggg tactaatcta ttaactttgt tacatatttt tagatactca ttggctcaac 3953581 aactgaggag gagacatttg tgaagaaaga cacaaggaaa tatatgatct actttttcgg 3953641 cgctttaggg ggactgctat atggttacga tacaggtgtt atctccggag cactcctgtt 3953701 tatcaataac gatattcctt taacgacatt gacagaagga ttggttgtca gcatgctgct 3953761 ccttggcgcg attttcggtt ctgccttgag cggcacatgc tcagaccgct ggggcaggag 3953821 aaaggttgta tttgtccttt ccatcatttt tattatcggt gcgctcgctt gcgcattttc 3953881 tcaaacaatc ggcatgctga ttgcatctag ggtgatactc gggttggccg tcggcggttc 3953941 aacggcactt gtgcccgtgt atctttccga aatggcaccg acgaaaattc gcgggacact 3954001 cggcacaatg aacaacttaa tgattgtcac cgggattttg ctcgcctata tcgttaacta 3954061 cctgttcaca ccgtttgaag cgtggcgctg gatggtcggt ctggctgcag tgcctgccgt 3954121 gcttctatta atcggcatcg ccttcatgcc ggaatcgcca agatggctcg tgaagcgcgg 3954181 cagcgaagaa gaagcgagac gcatcatgaa catcactcat gaccccaaag acatcgaaat 3954241 ggaattggca gagatgaagc aaggggaagc ggagaaaaaa gaaacgacac ttggcgtgct 3954301 gaaagccaag tggattcgcc ctatgcttct gattggcgtc ggccttgcca ttttccagca 3954361 ggcagtcggc attaacacgg tcatctacta cgcgccaacc atttttacga aggccggtct 3954421 tggcacatca gcttcggcgc tcggcacaat gggaatcggc atcctcaacg tcatcatgtg 3954481 tatcactgcc atgatcttaa ttgaccgtgt cggccgcaaa aaacttctga tctggggaag 3954541 tgtcggcatc acactgagcc ttgctgcttt atcaggcgtg ctcctgacac tggggctttc 3954601 cgcatcaaca gcgtggatga cagtagtctt tctcggtgtc tatatcgtct tttaccaggc 3954661 gacatggggt ccggtagtgt gggtgctcat gcctgagctc ttcccgtcca aagcacgcgg 3954721 agccgcgaca gggttcacga ctttggtgtt atcggcggct aacctgatcg tgtcgcttgt 3954781 cttcccgctg atgctaagcg cgatgggcat cgcatgggtc tttatggttt tctcagtcat 3954841 ttgtcttctc tcatttttct tcgcgttcta catggtaccg gaaaccaaag ggaaaagctt 3954901 ggaggaaatt gaagcaagcc tgaaaaaacg gtttaaaaag aagaaaagca cccaaaacca 3954961 agtgctgaat gagcgtacat tataaaaaaa ggaatcgtct ccttatgaga cgattccttt 3955021 ttctgtttac accatgacct tgcaaatatt gttcgtaaat tccacagggt cctgaatcgg 3955081 caggccttcg atgaggagcg cctgattgta cagaaggttt gtgtacaggc tcagcttctc 3955141 tttatcttgt tcaaacgcgt cctgcagtgt ttggaatacc tcgtgatttg ggttgatttc 3955201 cagcactttt tccgccttca cattttggct gtcaggcatc gcatttaaga ttttttccat 3955261 ctcaattgtc acttcgccgt cagcagcaag gcagactgga tgtgatttaa gccgttttga 3955321 gattctgacg tttttcactt tgtctgacag aatgtttttc atttcctcaa acagatcctt 3955381 atacttgctt tcctcttcct cggactgctt ttgatcctca tccgtgtcta tgccaaggtc 3955441 tccgcttgat acggacttga attctttttc ctgataagaa gccagcattt taattgcaaa 3955501 ctcatcgatg tcctcagtaa agtagaggat ttcatagcct ttgtccgcca ccatttccgt 3955561 ttgcggcagt ttctcaatgc ggtcgtaaga atcaccggtc gcgtaataaa tgaatttctg 3955621 ctcctctggc attctggaaa catactcgtc taagctgacc agttttttct cttttgaaga 3955681 gtagaataag aggagatcct tcaattgatc cttattcgcg ccaaaatcat tgtacacgcc 3955741 gaatttcagc tgtctgccga acgacttgta gaacgtctcg tatttctcgc ggtctttttt 3955801 caacaggctt tgcagctcgc ttttgatttt cttgctgatg tttttcgcga tcagcttcag 3955861 ctggcggtca tgctgcagca tttctctgga aatattcagc gacagatcct cagaatcgac 3955921 catgcccttc acaaagctga agtggtccgg tagcaggtct gcgcacttat tcatgatcag 3955981 cacgccattg gaatacagct ccaagccttt ctcatattcc ttggaatagt agtcaaacgg 3956041 catgttttca gggacgaata gaatcgcgtt gtagcgaacc gctccatcca cgctgatatg 3956101 aacgtgtgtc agcggtttat caaacccgta atgcttttca gcatagaatt tttcataatc 3956161 ctcatctgtc agctcgcttt tgttttttct ccagatcggc accatgctgt tgaccgtctg 3956221 ctcttcctgc acctcttcaa attcattttc gctgccttcc ttcggcttat taatggttgt 3956281 atccattttg atcgggtagc gaatgaagtc ggagtacttc ttgatgatcg cttttaaacg 3956341 atattcctct aaaaactcgt catagctgtc atcttctgtg ttctctttga ttttcaggat 3956401 aatgtctgta ccgacagaat ccttttcaca cggctcaatc gtatagccgt ctgcacccgc 3956461 agactcccat ttataagcct cttcgctgcc aagcgcttta ctgatgactg tcacgacatc 3956521 ggcaaccata aatgccgcgt aaaaaccgac accgaactgc ccgataatgt catgtccgtc 3956581 tttcagctcg ttttcctttt taaacgcgag ggaaccgctt tttgcaattg ttccaagatg 3956641 ctgttcaagc tcatcctttg tcattccgat ccccgtatca gagatggtta atgttctcgc 3956701 atctttgtca gctgcgacct ttatgtagta actgtcttta tcaaacgtaa gcgcatcgtc 3956761 cgtaagcgct ttgtaataga ttttgtcaat cgcatcactc gaattggaga ttaactcgcg 3956821 caggaaaatt tctttttggg tataaatgga gttaatcatc atatccagca agcgtttaga 3956881 ctctgcttta aactcttttt tcgccactct tgatcgctcc tttaccatta tgtaaaccct 3956941 tttcagcatc tatttatcac ataagatgac aattgtcaat tagattgata gatgcatata 3957001 tatgtaaatt taacattagt tggatttgtt ttcactcttt ttctcactca ttctcataaa 3957061 aaagagaggc ttcatcatcc tctctttttt tctgtgtcat tccaacggcc aaactcccgc 3957121 ttcatccata tatgcaccgg gtagaaaaac aaaccgaacg gtatcaaaaa caaaagatta 3957181 tgccatgaag cattcagaaa tgcgcttgca gtcaccggga acgtaatctc ttgcaataaa 3957241 aaagagatga cagtcagcac aacaaatgca gatggaatgg tcacgatgca ataaaacttg 3957301 agctccttct tatgctgtac cttcaaacat acaaacctcc caacaatttc taattcatct 3957361 taacatatgc tggcctttct tttctcgcat gtttatcact gcacatagcg ggaagacaaa 3957421 tagaaaaagg aggtctcgta tcatgggaag acttgaaaac aaaacagcag ttatcacagg 3957481 cgccgcgaca ggcattggtc aagcgacggc ggaggttttt gccaatgaag gcgcgcgtgt 3957541 gatcatcgga gatatcaata aagatcaaat ggaagaaaca gttgacgcaa tcagaaaaaa 3957601 cggaggacag gccgaatcct ttcacctcga tgtgtcagat gaaaacagtg tgaaagcatt 3957661 tgctgatcaa atcaaggatg catgcggaac gattgatatt ctgtttaata atgccggcgt 3957721 tgatcaggaa ggcggaaagg tgcacgaata tccggttgac ctgtttgacc gcattatcgc 3957781 cgtcgacctg cgcggcacat tcctttgcag caaatatttg attccgctca tgctcgaaaa 3957841 tggaggctcc atcatcaaca cctcctccat gtcaggccgt gccgcggacc ttgaccgctc 3957901 cggctacaac gccgcaaaag gcggtatcac caacctgaca aaggcaatgg caatcgacta 3957961 cgcacgaaac ggcatccgcg tcaattccat ttcaccgggc acgatcgaaa caccgctgat 3958021 tgacaaatta gcaggcacaa aagaacagga aatgggcgaa caattccgcg aagccaacaa 3958081 atggatcacg ccgctcggac gtcttggcca gcccaaagaa atggcaacag tggcactgtt 3958141 cctcgcatca gacgacagct catacgtcac aggagaagac atcaccgcag acggcggcat 3958201 catggcgtac acatggcctg ggaagatgct gattgaggag aaatggaagg aagaaacgaa 3958261 ataagagagg gagccccctc tctttttgtc ttttaaagca atacaacctt atatttcttc 3958321 acatccaaaa actgcaaaaa ctccctcgcc agcacttcag gcggatgcgc ctttccttca 3958381 tccagccgat acaaaagcaa cccgataatc attgcggata cataatgggc ataaagcttt 3958441 ttctctgcgt gaatatcagt ttgctgatgc agataaaacg attccagcgc tttgaacata 3958501 tcaggtatca catgaggaac accccattcc cgattgagaa aatggacaat gggcatgttt 3958561 gacaaagcag aaagcagaat ggcgagcgcc ttctccgctt cctttaagga aaattcattc 3958621 gggctggagg caatcgtcag gtgatcaatg atctccgcac atgatcgctg tatcatggtt 3958681 tggagcaatt cctccttatt ggcatagtga tcataaaagg ttgcacggcg gatattgctt 3958741 ttacgcgtaa tatctgaaat cgtgatgccc gcgtagtctt gtttctccgc caatacatcc 3958801 agaaatgcct tctgcagcgc ctctctcgtt cgaaccaccc gcctgtcgat ttgcttctcc 3958861 ttctctcgct ctcctggcac agcttttcca aacagccaat aaaaccgctt ttgagaaaca 3958921 agctcccata ccttctggct gatggcttca ggagacgcgg ccgcatcctc attcagccaa 3958981 tacaggataa tcgcgtacgt gtacaaggcc cgataatgtc cataaatgtc ccgttcaatc 3959041 ggcgttaaat tcacatggat cggagccagc agcacatcct gctgaaacac atccttaaaa 3959101 aaacgatgaa aatgtcctct gttcatcatc acagaaaaaa aggaacgatg ctcatgaaca 3959161 aaggacagcg tcggatgcac cgtttgccgt tttttgttca aatgaagggt atccatatga 3959221 ctgaaggcgt caaaaagcgc tttgcccagt ccttccttca tgtcttcgat cacatcctca 3959281 atgattgaaa acttatcctc ataataaagg tagagcgatc cgcggctcac tttggccttc 3959341 tcagcgattt ctttcattgt gatgtgttga atatctctat ctttcaataa agccagcagc 3959401 gcctctttca cttgagcttc ggcagattcc ggcacaaaag acacctccaa tcattagaca 3959461 gatcttagat atatgtacgg taacgtatag atggttcacc gttgtctttc ttacagaaaa 3959521 ggtaccacct tataataggt ccgagaaaag aagaaagcaa atgaggggga ttttacaatg 3959581 gaacagcaag taaaggacga catccagcgt gtctttcagc ttcagaaaaa acagcaaaaa 3959641 gccttgcgcg cttcaacagc ggaacagcgg agagaaaagc ttcaacgctt tttagattcc 3959701 gtcatcgccc atgaagaaga aatcatcgaa gcgatccgca aagacgtccg caaaccatat 3959761 cacgaagtca aaaaagcgga aatcgaagga acaaaaaaag cgattagaga taatatgaat 3959821 aacctggaac aatggatggc gcctaaagaa gtcggttcat cgttaagccc tgacgcaaac 3959881 ggaattctta tgtacgagcc taaaggcgtc acactcatcc tcggcccgtg gaactatccg 3959941 tttatgctga cgatggcgcc gcttgccgct tctctcgcag ccggaaacag cgcgattgtg 3960001 aagctgtccg atttcacgat gaacacgagc aacattgctg ctaaagtaat aagagacgct 3960061 tttgatgaaa aagaagtcgc gatttttgaa ggagaggttg aggtggcaac cgaactactt 3960121 gatcagccgt tcgaccatat tttcttcact ggaagcacaa atgtcgggaa aattgtcatg 3960181 acagcggctg ccaaacactt ggcatctgtc acacttgagc ttggcggcaa gagcccgacg 3960241 atcattgaca gtgaatacga tctgatggac gcagcgaaaa agatcgccgt cgggaaattc 3960301 gtaaacgccg gccaaacctg catcgcacct gattacctgt tcattaaaaa agacgttcag 3960361 gacaggttcg cggggatttt acaaacagtc gtcaacgctg gatttatgga ggatgatcat 3960421 accccagacc gcagcaaatt tacgcagatc gtcaatgacc gcaacttcaa ccgcgtcaaa 3960481 gatctgttcg acgatgccat cgaaagaggg gcggaagtgg tgttcggcgg cgtattcgat 3960541 gccagcgacc gcacgatctc gccaaccgtt ttgaaaaacg tcacgcctga catgaaaatc 3960601 atgcaggagg aaatcttcgc atcgatcctg ccaatgatga actatgaaga catcgacgag 3960661 gtcatcgatt acgtaaatga ccgcgataaa ccgcttgcac tttatgtgtt cagcaaaaac 3960721 caagatctga ttgacaacgt ccttcagcac acgacatcag gaaatgccgc catcaatgat 3960781 gtcgtcgtcc atttcagtga cgtcaacctg ccattcggcg gcgtcaacac aagcggaatc 3960841 ggctcctatc atggggtata cggattcaaa gagttttctc atgagaaggg tgtatttatt 3960901 caggccgctg aataatcgca tgatcaaaag gcgcttcctt agaggagcgc cttttattgt 3960961 aactccttga ccaaaagcaa ttcatcacgg ataggtattt tattatctgc cagtaaagga 3961021 atttcgggct tcatctttct ggccgtctcg actgcattca caaatagtcg atccaaccgg 3961081 taccctctct tctgataaaa cgctaatgca tgaatattat cattggttgt gatcagtttt 3961141 atttgtttga tatttctctc tctgcatgct tcctcggctt tctctagcag agctgttccg 3961201 atccctttat tctcaatgac actatccagc gaaatgattt cacaggcatc ttcttcaaat 3961261 atgtatgtaa taaggccaac aatctggtta tcatcgttga gcattccata accatctaat 3961321 tcatcgcagt tataaatacc gctagaaata accatttgcg gactgcccca gtgtttttga 3961381 aaaaacgcgg aaacaagatc tttaggtacc tggcatgtcg gaataatatt catattttcc 3961441 tccttttagc tgaacaaaaa taagagaatt aacaacctat tttatgtcat taatcccctt 3961501 atctagtatt tactagaact tataacttgt caaaagctgt ctgaatacca attgcgtgga 3961561 ttgataagga tcaaaatctg aatcctgaga ttggaagatt tgctctgggg tcaatgtctc 3961621 tgcgttctct gataacgttt gaatcagact ttccaaatat ccatttaact ctgatttgga 3961681 cgattcatgt agggattgat gatttacagc gagttctcta aatctgttat cactgattaa 3961741 tttttttcga agagctgcta gcatcaagtc aagccatgca ggctggccaa atgtaatatt 3961801 taaagctaac gttgcttgat cagatttggt ggagtgccat aaacctcttg gcaaatacag 3961861 catggttccc ggtgttaaat taacgatttc tgcatctggc agatcctctt ttggcggatc 3961921 tcctttccaa tatgactgta aatcatcagg atagtaagga gcctctgata aatcatagtg 3961981 ctgcattgga ttgctcacat tttcattctt ggcaagcttc catgttttct caccttgaat 3962041 ttgaaaaatc aagttggtgt aggcgtcaaa atgggctttg aatcccccgc catttttcgc 3962101 cgcgtaaaca atggctttgg aagaagtacc cgcaggcagt cttaattccg ctttgagttt 3962161 ttctatccac cttctgactt ggggaataaa taggtcggtg aaatcaaact ctaatgcagc 3962221 ccctttttca taccactcta aagcctctgc aggtgacaca agaaatctgt ctgtgatccc 3962281 ttcagattct tcaatcacag catcaccaac gaccatgact ggattattgt agatagccaa 3962341 tacgttttct agcgttctaa ccttttcaaa ccccggtatg cttgtaaatc tctccacttc 3962401 tcctctggct accaaaggtt ttacaggcca atattcttct aaaaactcac tcatcgttac 3962461 aggactgatg atagactcca aaaccgattc ggttacagca ctcatattat ccctcccaaa 3962521 aaaagtaact tcaccacaaa gatataacat ttttttctaa aagtaaatat tgacagaatt 3962581 atcagaggat tataatattt agttgtgcgt gatagcctat ttttttacaa ggaaggaggg 3962641 aaaaggatga aaaaggctta taagaaacct cgtctttttg aactgcgccg tgctgtagca 3962701 gctggcggcc attaatctca tatagcattt gacatctagt actctatttt aggagggatg 3962761 ctcaatgaaa aaagcttata agaaacctcg cctttttgaa ctgcgccgtg ctgtagcagc 3962821 tggcggccat taatctcata tagcatttga catctagtac tctattttag gagggatgct 3962881 caatgaaaaa agcttataag aaacctcgcc tttttgaatt gcgccgcgct gtagcagctg 3962941 gcggtcatta atcttatcca aaacgattaa cgtttgaggc tatcacgcca acttgataag 3963001 gaggatgctg aagatgatta cggctgaaga atgcagaacg tacaaagaat ttgttgatct 3963061 ttaccaatcc tatctttacc ccttgcttgg cgccagactg tcccggatgt attcccccaa 3963121 aaacaaagtc attatcgata tgggcacagg tccaggttat ttaagcattc agttggctaa 3963181 aagaacaaat gcgcacgtgc atgctgtcga tattaacccg gccatgcatg aaatcgctca 3963241 agaagaagct aaaaaaagcg gagtaagcag cctgatttca tttgatttgg aagatgtcca 3963301 ccatttatct tacgctgacc aatatgctga cttcatcgtc tcctactctt gcctgcatca 3963361 ttgggaagac gttgttaaag gacttaaaga gtgctataga gttctggctc cgggcggaaa 3963421 aattgtcatt ttggatacat ttaatcccca aggaagccat ttagagatta tgcgaaaaca 3963481 aatcaaagaa ccggaatact tcaggtttgt aagagaggca tttgaagaaa gttattcctt 3963541 tgaagacatt caccagtttg ttcaggatgc cggcattccc aattattcat tagaaacctt 3963601 tcacttttta ccggaggatt ttatagaaag cttagatgag ctggaggatg ctcccctgtg 3963661 ggaacaaaat gatcaaagta ctgatcatga aattgagtct gtcacatgga tgttaacgat 3963721 agaaaaagaa aaggaaggtg cattgtaatg atcaatgaat caactgtttt atccaaaaat 3963781 ccagaaatgc catcaagaaa atatttgaaa agcattatta tagagccggg catcacttta 3963841 aatgaaatgg catcagatat ttataaccat atcgacggca aggtcagcat acatgatatt 3963901 tgctcaaaaa tcgtcaatga atatgatgtt gattatcaaa cctgcttaga agattgtatg 3963961 gagctgtttg agttgcttat tgatcatgaa gcaatcaaag ttaagcaggg ggcatgagaa 3964021 ttggaaaaac aaaaagtgct tgctttacca gacgatgtac atgagctgag tacacaccgt 3964081 tctaaatcaa tcgtaaatta catcatcact ctgcttgcct ttgccaaaaa acaaggattg 3964141 actcatcaag atattgtaag ctggattcac gagcaatatg aggaaagagg atattatgat 3964201 gagtggagac acattaacag ccaacaacca gttggatcat ttgtggaact ctttataaaa 3964261 ggaagacgtt tactttatga caaaattgaa ttgtttgaaa cagaagataa atatgtcgta 3964321 aatacccaca cttggtatga aaaagaacct agtgaggcct ttttttattt tgaaattgat 3964381 cccgaagaat tttctgcgta cgcttccatt ctcgcaatcg aaaacgcaaa acgtctcgga 3964441 attaaaatcg atattgtaaa agaaacagat gtagagacag cttatatcta taaacatcaa 3964501 taacgctatt gggagggaga catatgtgcg ggctcgcggg tattataaat ctggctgctc 3964561 cccgttctca ggaatgtacc tttcatatat tgaaaggcat ggcagatgcc atcagctata 3964621 ggggaccgga tgatgaacaa tatcatattg attccaaagt cggctttgca tttcggcgat 3964681 tgtccattct tgaccttgta aatggacagc agcccttttt aaatgaggat ggatcaatcg 3964741 tcgttatggt aaatggagaa atttataact ataaagaact gaaggcttct ttacacaatc 3964801 atatgtttaa aacgacatct gattgtgaag taattgttca tttatatgaa gaaaaaggga 3964861 ttggatttgt agacgacatc atcggaatgt tttcaatagc catttgggac aaaaataaaa 3964921 acaaagtatt tttagttcgt gaccgctttg ggattaaacc gcttttttac acagagctaa 3964981 aacacgagct tatatttgcc tctgaaataa aatccctatt ttctcatcct cactgtcccc 3965041 gccaatttaa ttggaaagaa gcactctcag acatttggct aagcggggaa gcagccagta 3965101 atcataaaga aaccacttcc ttttttgtaa acatccaaaa tctcgatgct ggccattatc 3965161 tcgaaattaa tttgacaaca aatgaacgaa aaacagcaag ctattggtct ttacaggata 3965221 ttttgctcag gcaaggctat cgtgagaatc tccatcccga tgacctgatt gaaggatata 3965281 gagaactgct ggcagattca gtccatagat gtttacaaag cgacgttgaa gtcgggttgt 3965341 ttcttagcgg tggcattgat tcagctgcag tcgcacattt tgctgcagaa aaacaggatc 3965401 tccatacgtt tacagtatta agccaaagta catttacaaa tgaagatgca aaatatgccc 3965461 attggctggc taaagattta caccttccaa atcatcaggt tctctatcaa ttagggaacg 3965521 atgagttatt acaaccagag tcatataaac atttgttatg gatctgtgaa acaccgtttt 3965581 gcggaccgga acaattatat aagtttcatt tacataagta tgccaaagcg ataaggccaa 3965641 acctgaaagt catgctgacc ggccagggca gcgacgaatt taacggcggt tacagcacga 3965701 cactttcacc agccgagaac ccaagttggg aaggatttat tgaatcggtc aatacgatgg 3965761 agatgaaccg gctgcatcgg ctgcagggaa atatctttag agtgtgggag gagcattttg 3965821 gactttctcc tataaacctt tcttatttaa agagcaatga ttccagccaa gcagatcctt 3965881 ggcaatcgta tgtcctgaca aaataccgtg atctgcaaat gtataattgc tggcatgaag 3965941 atcggatcgc cgcggctaat catatcgaaa accgtgtacc gttcttggac catcggcttg 3966001 ttgaatgggt ttgcggaata cctgatggac tccgtaaaga cttgttatgg gataagtcgg 3966061 tattgcgaaa atcattaaca aatgagctgc atacaagcta tacccaccgg ccaaaggttc 3966121 cttttttcta tggtaaggac gtgagatata cacataaaat gatgtttcat cttctgaaga 3966181 aaaacaatta tcagcttata gaggaggcct tctctcacag cgatgcctcc agcataatac 3966241 aggttgaaca cattcatgcc atcatgacat atttggagga tgatcctgag tttacaaatt 3966301 ttgaattttt attaagactg gtgaacatgg gacttttatc aaaaatgact aaagaaaccc 3966361 cttctgttca attagacata accagccatt tagaatcgat aacaataaaa gactggcact 3966421 cacaggaagg tgatattgcc agtcgtttaa atatctcagc caataagtgt gaaggacaag 3966481 atattttggc gctaaaccct ggcgtcactc tgttaaggcc ggaaagcgat agtgagcatt 3966541 gcatctacat tgcggaagaa ggatttattc agtttattgt ttcggaggaa gacgtcggag 3966601 cttggctgca tattctctgc gatattaatg gaaaagacac acttcatacg attttagaca 3966661 gacatggtgt cagccttgaa gaagtggcca aatatattca agaagccatc gaacacaata 3966721 tcattttgat caaacaaaaa aatctgccag aaggagcata tagatgagca tcttttattc 3966781 gttttccgca cttaggggat tagcaatggg gattttttcg cctatttgga ttctttatct 3966841 gatatctaaa gattatgatt tccttcagat tggattaatg ggagcggtac ttgaaattgc 3966901 taagcttata tttgaagttc cttccggcgt ttttgctgat cgttatggaa ttaaaatttc 3966961 aattgccagt tcattctttt tctccatcct tacatgggcc ttcttccctt ttatcgattc 3967021 agctgctatt tgcatactgg ctatgatcat atgggcttta tcagattcct taatttccgg 3967081 ttcttttgaa acttggatga gccgtgtcgc aggggaagat cgattcggca aagaaatgat 3967141 gaaaaacaca caattgctaa tcactttttt aattattgga agtattgcca gcgggtattt 3967201 gtattcatta aatatctatt ttcctttcct gctcgttatg gtgatctact tattactatt 3967261 tatttggatg tctgtattta ttaaagtccc ttctgtttcc gaaacaaatc atggggatca 3967321 gaaccaacat gattcgataa agattatcaa agaaagttta aaaattatct ttaacaaaaa 3967381 aagggttctt ttaatcgtca tagccggttt ctttacagcc acagcctatg acacaatttc 3967441 ccgttactgg cagccttttt tgagtgattt aggcttttca gaaaagtcac tgggatatat 3967501 ttttgcccta ggagggttta ccgctctcgt tcttttgaca ttaaccatca ggttcgaaaa 3967561 gaagatcgaa aaaaatccat atctcgcttt aacctcattg gattccatgg gcatggtcat 3967621 gacttttcta ttgtctagag cattcaggcc gctgggcatt ccatgtacag cgtttttgct 3967681 tgcaattgaa gatattcatc atccgatcgt aacaagttac ttaaataagt ttttccccga 3967741 ttcatacaag aacacacttt tctcgttaaa ctcaggggta ggagcaattg gagaaattct 3967801 ttccggtgtc attttcggca tcatttccgc agcctttggg ctctctgcca tgtttgttgt 3967861 tgtagctgta tttctattaa tccctattat cctttatacg atagtgccta agattaaaga 3967921 caatgatatg aaagttcaga ttgaaaaatc ccagcaagtg taaatgtttt gtatcacagt 3967981 aagaagacct tcttattaaa agaaggtctt ctgctattct attcagttat ttcccaaaag 3968041 ccatcagctt cgtataactt ccaatataaa gtgttccgtc ctcagcgagc tgaggagaag 3968101 acacgacgtt gctgtcggtt tgatagctcc ataattcatt gccgtttgcg tctgccgcat 3968161 aaaccttcat atcatctgac ccgaaataaa ccgttccctt cgcgtcaatc agcggcgccg 3968221 ttctgacagg gccgtctgtg tagaatgacc agttcatatc cccgtttttg ctgatggaaa 3968281 acagctcgcc gcttcctgag ccgatgtaga tattgccatt atgatcaatc gcaggagatg 3968341 agctggagaa cccgtttagc gggaatgtcc atttcaaact gcctgttgat gtataagcat 3968401 acagctgtcc atcttggttg ccggcataaa tgtttccgtc cttatcaatc accggatatc 3968461 ctttaaacgc atttgacgtc gttctggacc atttcacctg tccggttccg gagttgatcg 3968521 cataaaacac gtaattatat gtgccgacat acacggtgcc gtttttggca agcaccggca 3968581 cagagctgac gaccccattt gttttcaact tccagcgctc tgtccaggtt gattttgacg 3968641 tcggtttgat cgcgtgaaca taattatcaa gtgttgagaa atacaacgtc ccgtctgaac 3968701 cgatcaccgt ttcagagctt ggcccgccgc ttaacggaac cgttgttaaa atttctcccg 3968761 tttctttgtc aataaaataa atctttttgt cataggatgc caaatagata acgccgttgg 3968821 tcccaagtac aggagattgc gtatatgttt ttccaagatt gcccgtcacc catttgactg 3968881 agccgtctgg attaaaggct ttcatttccc cgtctctgga atgaagatat actgtgccgt 3968941 ctccgtcaat cacagccccc gctccatttt gcggagtcgt tctgatgtcg ttttgccatt 3969001 tcagcgtccc gtctgtattt ccggcgaacc ggctttcgcg tgaccagtta aacatggcag 3969061 gcgccatcgc ttgtacatca tatcttcctg gcaaaaagcc agatgctcca ttattttgag 3969121 aaaacaccgt ttccgccgca taagcagctg tcggctgaag cactttggca gcgggcacat 3969181 cagaaacagc gccggccgaa acagccgccg ccaccgcagc tcccgcaatc aaagctttca 3969241 tacgaaatga cttgaccatc attgagaccc ccattatatg taacttctaa tttgtgacca 3969301 tcataacata ttcatccatt ttataaatct atttcacaaa aacatcacaa actagaaaac 3969361 tatgtaagag tattcacgga cgttttttca gcacccgatc gaaatgcagc cacaaaccaa 3969421 atgacgttga cagcagccgc agcgagacta actcccaaaa caaagatcac ctcagaaagc 3969481 agatggtcac taaagaaact aaacatcaag ataaaaccgg ccgaagacaa atgaatcaaa 3969541 agcccgaagc cgcaaagcac cgccatgaca tacctcattg catcgactcc gagcatataa 3969601 acgagaaatg gaatgaaata caagacaagg atcataccga cagctgacca catgccagct 3969661 gaattaaact gattggccgc cgctcccgtt ccggccagcg gcgaaagtga agccgccaca 3969721 atcacggcgc aaaaaagaaa cgcagaaatg gttgtcatga tcgccacgct attttttttt 3969781 gacatcaaac tcctccttta atagaaatat taaccttttt tattataagt aagttgaatg 3969841 ttatattcat tatattttta aaaaattcca gaatacatac acaaatgcta tgcttctttc 3969901 tagtatattt atatagtaaa aaacaaagga taaaagactc atttttctgt aatatcagga 3969961 ttttatcacc ataccatatt gcatgtacat gtttttcaaa gtatactatt ccagattaat 3970021 tcagaggaga gagaaaaata catggaaaaa ccagcaggat tttggattcg ttttttagct 3970081 tattttattg acggcattat tgtatctgtt cctagttata ttattctatt tattatcaat 3970141 tctgtgtttg tagctggggc tgtggcaaca aacccttaca tgacggaaga agagtattta 3970201 gtgaaataca tgacgcttgc atttttgcct actatgctga tcatgatcgt catcagcgtg 3970261 ttatattacg ggctgctcac agcttctaaa atgcaaggca cacttggcaa aaaaattctt 3970321 ggcctgaaag tggtcaatga acaaggtgaa cgggtttctg tcggacaggg aattggccgt 3970381 tactttgcct atatcttatc tggaatcatc ttttatatcg ggtttatcat gatcgccttt 3970441 ggagagaaaa aaggcctgca tgacatcatt tgcaaaacac gtgtcgtgta taaataatag 3970501 aaaaaagtct agacgccaat aggcatctag acttttgttt tctttgcaat aggctgccac 3970561 gacagatacg tagcgcttct ccacaaccac tcaaacggcc ccatccgaaa gacacgaagc 3970621 caaaggtggc tgaagaccat ttgaacggca caaacagcaa ttgtaatgag cacaccggca 3970681 gcagggtaca cttttccata caggcccaag ccgtaatgat aaaaaatcca agtacacaca 3970741 atagactgca tcaaataatt ggtaaatgcc atcctcccaa cagcggagaa tgattgcagc 3970801 actgttctca ctcttgtttt atgataaaga tagacaaccg ttgtaacata gaaaaacatg 3970861 aggaaaggcg cgccaatcag caaacatatt tctttatccg ttacactgta cagcacctgg 3970921 gcgccgatgc cgatgacaag cccagccatc cataatcgtt ttaatccttt gcgatgcttt 3970981 tccggttcat gcaaataccg tgattttgct gccgcagctc ccagcaaaaa catgctgaaa 3971041 tatggaatgg atgcaaagaa gtagttgagc ggattatacg taagcatgcc attcgaagac 3971101 atgtaaacaa gacggtcgtg gatccgctgt tctgcaatat ccttcaggct gccgcttcca 3971161 taaacatgaa tcgcttgttt tgcctgctgt gttaccgctt gtacccattc ctgtccgttt 3971221 gattgatcaa aacttgtcaa catgaacgga atggaaaaca gaagatacaa agagaccgcc 3971281 catatcagca gtgttttcgg ctttgctttt cgaaacaaga gcaggacaaa tccgagcagg 3971341 gcatattctg ttaaaatatc cccgtcccat atcaaaaagg catgaatcgt tccaaacaag 3971401 agaagcgcca ttaaccttct cacatataac ggaacaaacc gtttcccttt gttttctgct 3971461 ctctccatca tgacaaccat gccaaatcca aataaaaagg aaaacaataa aatacatttt 3971521 gtttgaatga agaatttcag tatgtctgcg gcggcaaaat cagcttcaga ccacttatcc 3971581 atgaaaaaat tctcttttcc aagcatagac aaatacatat ccggataact gaaatgtgcc 3971641 agattgacaa ataagatgcc gaaaatcgcc attcctctca gcacatcaag cacaccgatc 3971701 cgctcatttg ttaaagtcgg ctgtaatgaa gacatagcca tcacgctcct tttttctgta 3971761 ccttaagggt aggaaaaaat gaagcgcggt aacatcgatt taggtgtcag gccggcatga 3971821 aaaccttaca atcttgtcat ctttatggtt tcatcacctt taaatctaat gcttcgatat 3971881 tctgcaaaat gcgatcaaag cgcaaagcct gaggctcaca tgggaagatg tggccttcat 3971941 acgggtcgcc taacgtccgg aaaaacggtt caaataaacc aggaaccaat acgcccacca 3972001 tctttgtata gtgagaatca aggcgatagg agtgaacggt atttgcaggg acatgcagga 3972061 aatctcccgg attcagctga atttcctggc catctgtcca catcgtcatc tggccttcaa 3972121 ggcaataaaa tgtttctgta tgatattcat ggtagtgatc aacgattcgg tcacctttag 3972181 ggccttcaga tgatacgacg ataaactggc catctgtatt tttttgtgca gccacaatgc 3972241 ggtgaagctg atctccagtc aacagacgat ctccttctcc agattcaaga acgtatggaa 3972301 ccgctccatc tggcagctct gtaagttccg ctaatttggc cgaacatgca ggctttgctt 3972361 catctagaaa tacaatgtcc gctacagcgg ctgcttctgc aaatcgctcg tttgagactt 3972421 cttcgcttgc gtacggcgga tgttcagcgt gatcatacgg attcccaata acggaataca 3972481 agtgcgctac gtttcctttc atcgtgtaag acaccagtct tgttctgtgg ctctgcatcc 3972541 ggtagctgtg cggtgttccc gccggaatgt tggcataatc acctgatatt aataaatagc 3972601 gttcaccatc aagtgtcagt tccagtttcc cgtccaaaac gagaattcct tcatgtgtgt 3972661 ccttgtggac gtgaagcgga aaggcatctc cttttccccc ggaaagaagc acgatctcaa 3972721 acaaatcacc tgtgctcctc ccattcgcca tcaccgtggc aacctgtctg ccgaacagat 3972781 agcgctcgcc ttctccgctc cggagcaaat aaggcatttt ttctttaggc aatgaatgtg 3972841 tacataatgt tttcatatta tcgcttcctc caatttagac cagtctatat attatcattc 3972901 atttgtctag accgttctat ataattgtag gagaaaggat aacaaaatgc tacccttttt 3972961 ttctcaccag cactggtatt tgttcggcaa tgagaagaag aggcgttttg tctttattcg 3973021 ttaacgaaag catgatgccg ccctcaatca tcgaattaat cagcgttcca agctgatttg 3973081 cttcttcttc tgcaaatccg ttttccatta attttctggc aaaaaccgct tcccagcttt 3973141 taaacacctt catgcaaacc gtccgcagcg gttcactgat taacgctgtc tcactcgcca 3973201 gcaaaccgac tggaatacct ttaatgcttt ctgtgttgtc aaattggctg gctgtttttt 3973261 tgataaaaag ctgaatcgct tcaacaggat cagaggattc atccatgctt tgctgtatca 3973321 gatgttcaac gatcttacct gtatatgtaa ccgcttcaat tgctagttct tctttgccat 3973381 tcggaaaaaa gtgataaagc gatccttttg gagcaccgct ttcttttaca atctggttca 3973441 aacctgtcgc gtgatatcct tgcagctgga acagacgtga cgccgtgtga aggatttttt 3973501 cacgtgaatc tcctctgcta gtcattaaaa cattccctcc taggtatggt agagcgactt 3973561 atataatata aaaaagaacc ctgtgattgt caaaaggggt aagacccttc cggatggggt 3973621 aatgtacaaa aacagcgtct aggagggatc tctcaatgac aatcgatcat tcagtcacaa 3973681 atacagagca gcttgaacaa cagaaccccg ccataaaaac aaagctcaaa ctgaaaaagc 3973741 ttaaggatca ggtgatcgtc attaccggcg cttcaagcgg tatcggactt gtcacggcga 3973801 gaatggcagc tgaaaaaggc gcaaaggtcg tggcagcagc gcgaaatgaa gaggcgctga 3973861 aggagctcac tgatgaactt aaggaaaaag ggcacgacgc catatgggta aaggcggatg 3973921 tcggaaaaga agaggacgtc aaccgcatcg cagaaaccgc gatcagcaca ttcggccgct 3973981 ttgatacatg ggtcaacaat gcggccgtct cgactttcgg acacgccatg gacgtcaccg 3974041 tcgaagacat gaagcgcatg ttcgacacaa atttctgggg acctgtttac ggaacaagag 3974101 cggctgtcaa acactacacc ggcagaggtg tgccgggcgc actcattaat gtaggaagcc 3974161 tgttcggaga caggggaacg gtcattcaat ccacatatgc atctgccaaa tttgcgcttc 3974221 acggctggac ggaaagcatc cgaatggagc ttgaaaagga acaggcgccc gtctcggtaa 3974281 cgctcatcca cccgggcaga attgacacac catataacga gcatgcgcac agctacctcg 3974341 acaaacagcc ggctcattac cgctccatga tctatccgcc ggaagcggtc gccgaagcga 3974401 tcctgtttgc cgccgaacac cctaagcgcg acatgtacat cggctcacag gccaaagcca 3974461 tcgccatgct gggcgcgctt tttcctcgtc tgaccgacag actgatggaa aaaatcatgt 3974521 atcacagcca gcatgccgaa agaccgtcca atccgagaga agaaagcgct ctttatgatg 3974581 ctggctgcgg tatgcatgac agaggcacaa ataaaggatg gatgaggtca agaagctact 3974641 acacaaaagc gacgaagcgc ccaattgtat cggcggctgt tgttgccgga ctagtggctt 3974701 gggctgccgc caaacgatgc agataatctc tgaccataag aaaaacccat gctgttccag 3974761 cgaaccatgg gtttttcagc tgttaatcga taaaagcctt gttcatacgc tgcagcagct 3974821 cgccgaacat ctctttttcc tgtgttgacc attctttcag catctgttca taacgttcaa 3974881 ggcgcttttg ctgatcggct tttaatagtt gtttgccgag ttttgtaatg gtaaacaggc 3974941 tgactctccc atcagacggg tctgagaaac gatagatgag ctcctttgcc tctaatgcag 3975001 ctgcttgtct tgaaagagta gaaatatcaa gcttaaacga ttcagccaat tccttaacac 3975061 gagcaggccc aaactcatcc aattgtctca gtaataagta cgaagatctc tccaaattcc 3975121 ctgttctttt ctccgattga tccagataaa cagctctcct gataaaagtc gtcagctcat 3975181 attcaattaa ttcaactgga ttttgatttt gcaatcgctc tcgctcccta ttccaatctc 3975241 cggcattgac aacatcatat atacttgtat aatacaaatg tacattaact gaataaatac 3975301 aagtcgttat atgactaaat caattattat acttgtatag tacaatcata taaaaagaaa 3975361 gtaaagcgat tcctcagaac catcctagaa gcaagcacca gaaaggagga agctgttctg 3975421 attggagagc agcacttgat gtgaaagtca tacgaattat tttgcaagtg ttgatattat 3975481 atgtattttt tatgatcggg gaagccattc agcatctgtt tcatttaccc gtgtcaggaa 3975541 gcatcgttgg attggtattg cttctgatct gcttgggcct ccgtattgtt cccgtctcca 3975601 tcattgaaga cggagcaggg tttttattat ccttccttcc attgttgttc atcccggcaa 3975661 tgacaggagt gataaactat ccgtctctca tttcattcaa tggcctgatg ctgctgatta 3975721 cagtcgttct cagcaccatc gtcacgatca ttgcggctgg attcgccagc cagctattag 3975781 agaaaaaagc aaaaaaacgg gaggagaaag agaaatgcag caagcatgta tcgcgatcat 3975841 tataattctt ttaacagttg ccgcttattt agcgatggtc aaactctata agcgattccc 3975901 gcttccattt ctgatccctg ttctgacaac gacaattttg attgtagcgg ctttgatgat 3975961 gtttcatgtt tcctatgaag gctatatgat cggggggaaa tggatcaatt ctttgcttgg 3976021 gccggctgtt gtggcgctgg cctatccgct ttataagcaa tggcatatca ttgtcaaaca 3976081 ttgtgttccc attttaggcg gcgtcctggt cggcttatgc atgggaatga tcagcgggct 3976141 gatcttcgca gaagcattcg ggattgatca tgatctctta ttatccattc tgccaaaatc 3976201 gatcacaacc cctgtcgcta ttcagatcgc cgccggtctt ggcggcgtcc cttccatgac 3976261 agtcgtattt gtcatgattg cgggcttttc aggcgtcatc ctcgggccgc ttttcctaaa 3976321 atggcttcgc atacgcagct ccctaggaca aggcattgca ttaggcagcg cctcccatgc 3976381 actgggtacc tccaaagcgt tggaatatgg ggaattggcc gtatccatga gttccgtctc 3976441 catgacgctt tgtgcggtgc tcggctcatt cttcggcccg ctcgtcgtct ggctgtttca 3976501 tatttaacaa agaaagactg ccccggggga gggcagtctt tttcgtttaa gaagcaaaaa 3976561 aatcaatcaa cggctgaaag tccttagata aatcaacgtc attcggttct gcttgaagca 3976621 ggcggtcaat catacgctcc agctcctcaa catcattctt atccgtatat tcaatgaagt 3976681 ttaagctttc aagccaatcc cgatatgaat gtttggcttt gccatagctg tttccaaaga 3976741 caaggcaagg tgttttggtg ataatcgaga aaatcatcgc gtgaaggcgg tcggtaatca 3976801 ccaatttact ggagccgatg cggtccagca tctccataaa atgcttttca cgatcagcgt 3976861 aatcgatggt gtctaccgta tccagcaccg tatcggtacg ctctgtgtaa gttgtttttt 3976921 ctgcccattg cttcatctgt gaaataaaat cttcgtcagt cactttctcc ttatccgctc 3976981 ttaaaataaa gagaacgccg tcccgctcga gctctcgcgg cacaatatcc aaggaaagca 3977041 ccatgtccgg tgtaaagatc acattggagt tgaaggtctc tttcacaaca tccagtgttt 3977101 gcgtctcacg cgcagcaatc gttaagtttg tattttgatg gtacgcatcc tgtgtttttt 3977161 tcttttcctt ctgtccttcc tctgtatcct caaaataaac ggattgtggc agagaaattg 3977221 atttgtagtc tttaaacgcc gaaaagacct ttcttctgtc ttcctcaata tcgagataaa 3977281 ggtttcctaa attccctccg cctgtaaagc agacaatatc gtcttcacga atgatctcct 3977341 tcaccagttc aatgccctca tccgtcgcat aatccataat ctcaatgtat tcataatacg 3977401 gaaaatgatt tttgataaat ttctcttccg catacgcaat cgcttggtcg ccaatgtttg 3977461 tgtagctagg ggaaccaaac aaaaatactt ttcgtttatc atttaacaga gcttccggct 3977521 ccacatttgg cgcaatgcct tttactagtt ttttgccttt gatttcttgt acagtcatat 3977581 ctgcgtcctc cttctgggat gaattcctca ttgtgtgtta actgtctcta cccaaaaaga 3977641 aggatggcta tgcattggca tgtgcatcgg ctatatcaga aacatcgttt tcgccaattt 3977701 gatagacgct gcaatgtccc gcgccgttct ttccatatat tccgcggcat gttcaaacgc 3977761 gtcttctagt ggcacggctc cggggacgat gctgaaaagc gcatcgattc cgtgttgata 3977821 gacggcatta ctgtctcggg aaattgatcc cgcaatgccg ataacgggca catcgtatga 3977881 tttagcggcc ttggccaccc cgatcggtgt ttttccatga accgtttggc tgtcgattcg 3977941 tccctcgccg gtaatcacaa ggtctgcatc ctgaacgata ctttcaaaat caaccgcttc 3978001 aaggacaata tcaatgcctc ttttcaggtc agcctgaaga taagttagca ggctccatcc 3978061 aagaccgccc gctgcaccgg cgccctctgt atctcggaag gttgatccga gcgctttttc 3978121 tgccatatca gcgaaatggc ttacgttctg gtctagtaca tccaacatgt cggccgtcgc 3978181 gcctttttgc ggcccgaaaa cagccgtagc accctttggt cctgttaacg gattgtccac 3978241 gtcacaggca acttccagtt tgacattccg caatctggaa tcaagcccgc tcacatctat 3978301 tgatgcaagc tgagataacg cgccgccccc tgggccaatc tcgctgcctg agttatcaag 3978361 aagccttccg cccaatgcct gaatcatccc ggctcccccg tcgttcgtgg cgcttccgcc 3978421 gattccgatg atcaatcgct ccgctcccgc atcaagagct gctccgatta attctcccgt 3978481 tccccttgtt gtagtgatga gcggatttcg cttatctaca ggcaccagat gcagccctga 3978541 agcagcagcc atttcaatca cagctgttct cccatctccc atcatgccaa agaaagctct 3978601 caccggttcc cccagcggcc ctgtgacaac ttgctctatg atccttccat tggtcgcatc 3978661 gaccagagat tgaacggttc cctcgccgcc atccgccacc ggcaattttc tgtaatcagc 3978721 acccggaaag accgatttga aacctctttc tatcgcttcg gctgcctcca gagctgataa 3978781 gctttcctta aaagaatcag gtgcaatgat gattttcatc caaatcgcct ctttcaaaac 3978841 atgattcact taacctattg atctccaatg taccataatt gatctggaaa tacataccat 3978901 gcaatatggt aaaaatttaa ataaaaatta gaaatgaaag tgtttgcata aaagaaatat 3978961 tcacgttatc atacttgtat acaagtatac tccttgagtg aggaaggtga gtgtatgcta 3979021 gactccaaag acctgttgta tcccgcaaaa tggctctcaa aagcgtcaac cggagttcgt 3979081 gtcgcatacg agctgagaat gcggatcgtt tcaggtctga ttgaaagcgg taccatttta 3979141 tcagaaaata caatcgccgc cgagttttca gtaagccgtt cgccggttcg cgaagcgcta 3979201 aaaatactcg catccgaaaa aatcatccgc ttagaacgaa tgggagcggt cgtaattggt 3979261 ttaactgaga agaaaatcgc ggaaatttat gatgtgcggt tactattaga aacatttgtc 3979321 tttgaacggc ttgtcaaaat agacattgag cctttagtta aggatctcag caaaattctt 3979381 gaaatgatga aagtctcaat caaatatgag gatgctgacg aattttcatt tcaagatgtg 3979441 ctgttccatg aaacgattat ccgagcgatt gatcattcat acattcagat gatctggaac 3979501 aatctaaaac ccgtcatgga aagctttatt cttttatcga tgcgggtacg gttaaaggaa 3979561 aagtatgaag acttcacaag gattttagat aaccacgagc tttatattca agccatcaaa 3979621 acaaaggata gggcgctgat gattcagtct cttcaccaaa actttgatga tgtgcaggat 3979681 aaggtagaag acctatggct ctcacaacaa atgctggcaa aaggagctga atacaacaat 3979741 gactagttat atgttaggaa tcgatatcgg cacgacaagc acaaaagctg tgctgttcag 3979801 tgaaaacgga gatgtggtac agaaagaaag catcggctac ccgctctata caccggacat 3979861 ctcaacagct gaacaaaatc cggaagagat ttttcaggca gtcatccata caacagcgag 3979921 aattacaaaa cagcatcccg aaaaacggat ctctttcatt tcgttcagca gcgccatgca 3979981 cagcgtcatt gcaatcgacg aaaatgacaa gccgctgacg ccatgcatta catgggccga 3980041 caacagaagt gaaggctggg cgcataagat caaagaggaa ttgaacggac atgaggtgta 3980101 caaacggacg ggaacaccga ttcatccgat ggcaccgtta agtaaaattg cctggatcac 3980161 gaatgaaaga aaagaaatcg cttccaaggc aaaaaaatat atcggcatca aagaatacat 3980221 ttttaaacag ctgttcaatg agtatgtcat cgattactca ttggcatcag cgacaggcat 3980281 gatgaacctg aagggcttgg attgggacga agaggcactg cgcatcgcag gcatcacgcc 3980341 ggatcactta tccaaactcg tgccgacaac cgagatcttt cagcactgca gcccggaaat 3980401 agcgatccaa atgggaatcg atccggaaac gccttttgtc atcggcgcca gcgacggcgt 3980461 gctgtccaac ctcggcgtca acgccattaa aaagggtgaa atcgccgtca ccatcggtac 3980521 aagcggtgcc attcggacga ttattgacaa gccgcaaacc gatgaaaaag ggagaatttt 3980581 ttgctatgcc ttgacggaca agcattgggt tattggggga cctgtgaaca atgggggcat 3980641 cgtccttcgc tggatcagag acgagtttgc ctcctccgaa atcgaaacag cgacacggct 3980701 gggcattgat ccatatgacg tgctgacgaa aattgcccaa cgcgtcagac ccggttctga 3980761 cggtctgctg ttccacccat atctcgccgg agaacgcgct ccgttgtgga atccggatgt 3980821 acgcggctca tttttcggct tgaccatgtc gcataagaaa gagcatatga tacgcgcggc 3980881 attggaaggc gtcatttaca acctgtacac ggtgttcttg gcgttaactg aatgcatgga 3980941 tggcccggta acccgcatcc aagcgacagg gggttttgca aggtcggagg tttggcgcca 3981001 aatgatgtcg gatatcttcg aatcagaggt tgtcgttccg gaaagctacg aaagctcatg 3981061 tctcggcgcc tgcattttag gcctgtatgc aacaggaaaa atcgattctt tcgacgccgt 3981121 gtccgatatg atcggcagca catacagaca tacgccgatc gaagactcag ccaaggaata 3981181 cagaacatta atgccgattt tcatcaatct atcaagatta ttagaaaatc aatatacaca 3981241 aattgcagat tatcagaggg gcttaatcac acacaaatag tacatgacat gaaggggagg 3981301 gcattaccat gccgttaatc atcgttgcac ttgggatctt agcattacta tttctgatta 3981361 tgggcttaaa attaaacaca tttatttccc tgctggtcgt atcgttcggc gtggcactgg 3981421 cactcgggat gccgttcgat aaagttgtca gctccatcga agcaggaata ggggggactc 3981481 ttggccacat cgcgctcatc ttcggactcg gtgcgatgct gggcaaactg atcgcggatt 3981541 caggaggcgc acagcgcatt gcgatgacgc tcgtcaacaa attcggtgag aaaaatattc 3981601 aatgggccgt tgtcattgcc tcattcatta ttgggattgc gttatttttt gaagtaggac 3981661 tggttctatt aattccgatt gtctttgcga tttcaagaga attgaagatt tctattttat 3981721 ttctcggaat cccgatggtc gcggcactat ccgtcacaca cggtttcctg ccgccgcacc 3981781 cgggacctac ggcgatcgcc ggtgagtatg gcgcaaacat tggagaagtg ctgctgtacg 3981841 gctttatcgt tgctgttccg acagtgctca ttgcagggcc gttatttaca aagttcgcga 3981901 aaaaaatcgt tcctgcatca tttgcgaaaa acggcaatat tgcatcactc ggcacacaaa 3981961 aaacatttaa ccttgaagaa acacccggct ttggaatcag tgtctttact gcaatgctcc 3982021 cgattatcat catgtcggtc gcgaccatta tcgacctgct tcaagaaaca atcgggtttg 3982081 cagataacgg agttttagct tttatcagat tgattggaaa cgcatcgact gctatgatta 3982141 tttcgttatt ggtcgcagtc tatacaatgg gcatcaagcg caacattcca gtcaaaaccg 3982201 tgatggattc ttgttcaact gccatttcac aaatcggcat gatgcttttg atcatcggag 3982261 gaggcggcgc cttcaaacaa gtgctgatca acggcggtgt cggcgattac gtagcagact 3982321 tattcaaagg aacggcatta tcgccaatca ttctggcatg gctcatcgca gcgatcctgc 3982381 gcatttctct aggatcggcg actgttgccg cactaagcac aacaggtctg gtcattccgt 3982441 tattgggcca ttctgatgtt aacctggcgt tagtcgtact cgcaacagga gccggaagtg 3982501 tcatcgcttc acacgtcaat gacgccggct tctggatgtt caaggaatac ttcggattaa 3982561 gcatgaaaga aacattcgcc acatggacat tgctggaaac cattatttcc gttgctggac 3982621 tgggattcat tttattgtta agtttagttg tatgaaatta agaaggagct gtaacacatg 3982681 ttcaattcga ttggtgtcat aggcttaggc gtaatgggaa gcaacatcgc cttaaacatg 3982741 gcaaataaag gcgaaaacgt cgctgtctat aattacacca gagatttaac ggaccagctt 3982801 atccaaaagc tggatggaca atctctcagc ccgtattacg agcttgagga ctttgttcaa 3982861 tcgttagaaa aaccaagaaa aatctttttg atggtcacag cgggaaaacc cgtagattcc 3982921 gtcatccaat cattaaagcc tttgcttgaa gaaggcgacg tcatcatgga cggaggaaac 3982981 tcccactatg aagacacaga aagaagatat gacgagctga aggaaaaagg gatcggctac 3983041 ctgggagtcg gcatttccgg cggtgaagtc ggtgcgttaa cagggccttc catcatgccg 3983101 ggcggagatc gcgacgtcta tgagaaagcc gctcctatcc tgacgaaaat cgcagcccaa 3983161 gtcggagatg acccttgctg tgtctatatc ggaccaaaag gggcagggca ctttacaaaa 3983221 atggtgcaca acggcattga atatgccgac atgcagctga ttgcagaagc ttatacgttt 3983281 ctaagagaaa cgcttcgtct gccgctagat gaaattgcat ctatttttga aacatggaat 3983341 caaggtgagc tgaaaagcta tttaatagag attacagctg agattttacg caaaaaagac 3983401 gaaaaaacag gacagcctct gatcgatgtc atccttgata aaaccggcca aaaaggcacc 3983461 ggaaaatgga cgagcatgca ggcgattgat aacggcatcc cgtccacgat catcacagag 3983521 tccttgttcg cccgctactt gtcatcttta aaagaagaac ggatggcagc tcaagatgta 3983581 ttagcaggcc cggaagccga agaaaaacac ttggataaag acacttggat tgaatacgtc 3983641 agacaggctc tttacatggg gaaagtatgc gcctatgcac aaggctttgc ccaatataag 3983701 atgtcatctg agctttacgg ctggaatctg ccgctcaaag acatcgcctt gattttccga 3983761 ggcggctgca tcatccgcgc tgatttccta aacgtgatca gcgaagcatt cagtgagcag 3983821 ccaaatctgg ctaacctgct gatcgcgcct tatttcacag ataagctcca tgcctatcaa 3983881 acaggcctgc gaaaagtcgt ttgcgagggt atcagcaccg gaatctcttt cccatgctta 3983941 actaccgcgc tctcttatta cgacggctac cgcacagggc gttccaatgc gaacctcttg 3984001 caggcacagc gcgattactt tggcgctcac acgtacgaac ggactgatat ggacggcgtc 3984061 ttccatacga attggtctga ataacctgta ttaaaaacac ggtcagtttc aactgaaccg 3984121 tgtttttttc ttctatccca aacaacagaa gacataagtt atgttttaaa tatcataaac 3984181 agtgatacaa taatagctag aaacaatccc caagatcatc atgtgacagc agattgctgt 3984241 tccgttctat tctgcttttg gccattgtcc tttgcccttg accatggtgt cataaaatgt 3984301 tcaaatgcca aaacggcctg gcattctgat ttacaaaagt ccctgaaaac cttatctaat 3984361 tgagaatcag cctctcattt attataaaag aaatgcctaa atcctacctg tcacaccttt 3984421 attaagatga aaaaaagtag gttatggctt gacaaaaaat atatattaat taataattca 3984481 tatataatta gaattattat tgaaagcgat tatgctttct aatacatttt taggaggaat 3984541 atacattatg tctttaatcg gtaaagaagt acttccattc gaagcaaaag cattcaaaaa 3984601 cggtgaattc atcgatgtaa caaacgaaga tttgaaaggc caatggagcg tattctgctt 3984661 ctacccagca gatttctctt tcgtatgccc aactgagctt gaagatcttc aagaacaata 3984721 tgctgcactt aaagaattag gtgttgaagt atactctgtt tctacagata ctcacttcgt 3984781 acacaaaggc tggcatgaca gctctgaaaa aatcagcaaa atcacttacg caatgatcgg 3984841 tgacccatct caaacgatct ctcgcaactt cgatgttctt gacgaagaaa ctggccttgc 3984901 tgaccgcgga acattcatca tcgatccaga cggcgttatc caaactgttg aaatcaatgc 3984961 aggcggtatc ggccgtgacg caagcaacct tgtaaacaaa gtaaaagcag ctcaatacgt 3985021 tcgtcaaaac ccaggtgaag tttgcccggc taaatgggaa gaaggcggcg aaactcttac 3985081 acctagcctt gatctagtag gtaaaatcta aggagtgcat tcaattggta cttgatgcaa 3985141 atatcaaagc acaattaaat caatatatgc agctaattga gaatgacatt gttctcaaag 3985201 ttagcgcagg cgaagatgac acttctaagg acatgctggc tctcgttgat gagctggctt 3985261 ccatgtcatc gaaaatttca gttgaaaaag ctgaattaaa cagaacgccg agcttcagtg 3985321 tcaatcgtgt cggagaagac actggcgtga ctttcgccgg tatccctctg ggccacgaat 3985381 tcacatcatt agtgttggcg ttgctccaag tgagcggcag accgcctaag gtagaccaaa 3985441 aagtcattga tcaggtgaag aagatcagtg gtgaatacca cttcgaatct tatatcagcc 3985501 tgacatgcca caactgtcct gatgttgtac aagctttaaa catgatgagc gtgctgaacc 3985561 cgaacattac gcacacgatg attgacggtg cagcatacaa agcagaagtt gaaagcaaaa 3985621 acatcatggc agtgccgacc gtttacctga atggcgaatc cttcggaagc ggccgtatga 3985681 cgcttgaaga aattcttgcg aaaatgggca gcggcacaga tgcatctgag tttgctgaca 3985741 aagagccgtt tgacgttctt gtggtcggag gcggacctgc tggtgcaagt gcagcgatct 3985801 acactgcacg taaaggcatc cgaactggtg ttgtcgctga gcgcttcggc ggacaggttc 3985861 tcgacaccat gagcatcgaa aacttcatca gcgtcaaagc gacggaagga ccgaagctag 3985921 cggcaagtct tgaagagcat gtgaaggaat atgatattga tgtcatgaac cttcagcgtg 3985981 cgaaacgcct tgagaagaaa gatctgttcg aacttgaact cgaaaacggc gctgtcctga 3986041 aaagtaaaac agtgatcctt tcaacaggtg cacgctggcg caatgtcaac gtccccggtg 3986101 aacaagagtt caaaaacaaa ggtgtcgcat actgcccgca ctgtgatggg ccattgtttg 3986161 aaggcaaaga cgttgcggta atcggcggcg gaaactctgg tatcgaagca gcgattgatc 3986221 ttgcaggtat tgtcaatcac gttactgtac tagaattcgc gccggaactg aaagcagacg 3986281 aagtcctgca aaaacgtctc tacagcctgc ctaacgttac tgtcgtgaaa aacgcacaaa 3986341 caaaagaaat cacaggtgat cagagtgtta acggcatcac atatgtagac cgcgaaacag 3986401 gcgaagaaaa acacgttgaa cttcaaggtg tattcgtcca aatcggtctc gtgccaaaca 3986461 cagaatggtt agaaggaacg gttgaacgca accgcatggg cgaaattatt gtcgacaaac 3986521 acggcgcaac aagcgtacca ggcttatttg ctgccggcga ctgcacagac agtgcgtaca 3986581 accaaattat tatttctatg ggatcaggtg caactgccgc cctcggcgcg tttgattacc 3986641 taatccgtaa ctaatataag aaatccgcta tattgccaga ttggcaggat agcggatttt 3986701 tctttttcta cagaaaaaaa ccgaaccagg cactacggta aaagtgctcg attcgagcgc 3986761 ttcttatagt tcctcaccat tcgtttgaat gacattttta taccactcaa aggagtcttt 3986821 cttatatcgt ttcatggatc cgtttccttc attgtcacga tcaacataga tcatgccgta 3986881 gcgttttttc atttcgccag ttgtgaagga gacaatatca ataatgcccc acggcgtgta 3986941 gccaattaaa tcaacaccat cgtacgtgac cgcttttttc aatgcttcaa tatgcgattt 3987001 taaatattga atgcgttccg gatcatgaac cttgccgtcc tcctccagcg tatccactgc 3987061 gccaaagcca ttttcaacga tgaataacgg gatttggtat cggtcataaa aacgatttaa 3987121 cgtatatctc aacccggttg gatcaatcgc ccatccccag tcactcgaag tgatgtacgg 3987181 attttcgaca ccattcggca agccgccatt tacaatatcg ccagtgttat catttttcac 3987241 atcgcttttc acagttgttg acatgtaata gctgaagcct aagtaatcga cggttccgtt 3987301 tcttaaaatc tcatcatcgc cgtcttcgaa tgtgatgttg tagccttcgc gttcaaattc 3987361 cttcaacgcg tagcttggat aataaccgcg aacctgcaca tcagggaaga aatagcgctg 3987421 cctcatttct tcttcagcca gcatcacatc ttcaggattg gaggagaaag gataaatcgg 3987481 cacgtgtgat accatggccc caatctggaa ctctggattg atgtcttttc cttttgccac 3987541 tgctaaggcg ctcgccacta attcatggtg cgccgtttga tacatgactt ccttggcgtt 3987601 ttcgttttcg ccaaccacaa cacctgaatt cgtccatagg aacagcggat tgttcacatc 3987661 catttggttg ttaatctcgt taaatgtcat ccagtacttc actttatctt tgtaacgggt 3987721 aaagcaagcc tctgcgaagt tgacgaagaa gtccacgact ttccggtttc tgaagccgcc 3987781 atattctctt gccaggtgca gcggcatttc aaagtgagac agggtaatga ccggctcgat 3987841 cccatgcttc agcaattcat caaacacatc atcataaaac tgcaaaccag cttcgttcgg 3987901 ttcagcctca tcgcctttcg gaaaaatccg gctccagccg atggacgtcc gcagacattt 3987961 taatcccatt tccgcaaaca aagcgatatc ttccttgtat ctgtgataga aatcaatggc 3988021 ttcatggttt ggataaaatt cgttttcttc aatcgtgtca gtgatttttc tcggcacgcc 3988081 gtgcgcaccc gctgtcatca catcgacgac actcggccct ttaccgcctt gattccatcc 3988141 gccttcaaat tggtgggcag ctaaagcacc gccccataaa aaatcctttg gcatgtttcc 3988201 catgtttaat tcctcctcag cttacgactg taaatatttt ttgatgtaat gcactttcct 3988261 caatgtcttc aatgaaagct ttatcaaact caacaagcac ttcgcctttt ttgacggtat 3988321 cgccttcttt taccttcaag gaaaaaggcg tgccgtcaaa tgtcaccgta tccagcccga 3988381 tgtgcgcaag caattcgacg ccggacgctg aacgcaggcc aatcgcatgc tttgtaggcg 3988441 taaccatgac aaccgtaatg acgccgggat ggtagcatcg atttcacgat atccttcgct 3988501 ttaggggtag accgcttcag caccaatcga agtctggtag cgcagcgaga agccccaatc 3988561 acattctctt ccccgcctac ggcctctaaa atgtcttttg ctagtctcgt ataatctctc 3988621 actttccccg acatttcacc caccccttcg ttttggttac gctttcatta taattgtaac 3988681 ggtataattt atcaattccg aaacaaaata tttacgcact aactatcatt gtaagcggtt 3988741 tatgctataa ttttgacaag tgaaactaaa cgaataaatg aggaatgcgt atgttaaaat 3988801 accagcaaat cgcaacggaa attgaaacat atatagaaga acaccagctt cagcagggag 3988861 acaaactgcc agtcctagaa accctcatgg cccagtttga agtcagcaaa agcaccatca 3988921 caaagtccct cgagctatta gagcaaaaag gcgcgatctt tcaggtcaga ggaagcggca 3988981 ttttcgtcag aaaacataaa cgaaaaggct atatcagcct tctgtcgaat cagggattta 3989041 aaaaagatct cgaggatttc aacgtcacct caaaagtcat cgaactggac gtgagaaagc 3989101 caacaccgga agcggcggaa aacctgaaca tcggaatgga cgaggacatc tactatgtca 3989161 aaagggtccg ctacatcaac ggccagaccc tttgctacga agaatcctat tacaccaaat 3989221 ccatcgtgac gtatttaaac aacgaaatcg tctcccactc catcttccat tacatccggg 3989281 aaggactggg gttgaagatt ggtttttctg atttgtttct gcacgtgggc cagcttaatg 3989341 aggaagaagc ggaatatttg ggattagagg ctggactgcc gaagctgtat atagaaagta 3989401 tttttcacct gacaaatggg cagccgtttg attactcgaa gatttcgtat aattatgagc 3989461 agtcgcagtt tgtggtacag gctaatagtt ttttattata gggctcttca ctacggtagg 3989521 tggtcgacat gtacaaaatt atcattcctg ccatactagc catctttgcg ctctggatac 3989581 tcttacagat ttcactagag atgagcatcg ttaagaatcc aatgaactac tttatcgtat 3989641 tcattatctt tttcctcttt gtaaagatgg tgaaagaaaa acaataatag tttgggcgat 3989701 gcaaacagaa aaacatcctt cccttaacaa actcagccag tcacatgcat taatcttgat 3989761 gttaatgata tataggtgca cataaaaagc tacttcattg tgaagtagct ccctttatta 3989821 aaggcccatt ttgatccatc tagttttaga aaagcgaagg acaatcgcat ttatgataat 3989881 aattgaaact aaatacaaaa taataaataa aacatcatta ctcccaagtg tcatgttatc 3989941 agattgcagc actctttcta ttcgggggta catagtgtta cctgcctcaa aaggagcaat 3990001 gaaaccaaac gttttattgc ttatagctac taagataaca gaagtcatcc aataaacgat 3990061 actgacacct atactaatta atatattagg acataacacg cttatagttc cgataattag 3990121 aatatactgc agtataactg cagaaaataa aaaaagtaat aatgcaaaat gcgaaaaatc 3990181 atggtacatc aacgatatga ttagcaggcc tagcgttata aatgcaaaac attctaaaaa 3990241 taaaacagct atctttttat aaaagaaagt atagatgttc tctccaatta acttgtaaaa 3990301 gagaatattt ttgtttgaat actctctatt aataaagaaa gctataacaa atgaaaataa 3990361 catcaaacca aactgggtcg caacagtata ggagctaaag aaaaacattt caggtgtaac 3990421 attactgact ttatcgattc caacaagtaa aaaataaccc agcaaaaata aaaatacaaa 3990481 cattgctcct aaaataatga taactttgtt gctaatactc tttttaaact ctaatttcat 3990541 ctcaagcccc cactgtttta ttactcattt atatacactt caattaattt atccactgaa 3990601 tgatattgtt gaatttcttg gtgattaaat atataataat ccccttctat cgcctttaaa 3990661 tcagacaaat catgtgtaat gttgatgata atcttctcgg ggttctcctg aatatacttg 3990721 tttaagaagc catgaatctc tataaccgtt tttttgtcta atgaattcgt tatttcatct 3990781 aaaacaataa tatttttatc ctctaataag aaactgagca attttaattt ttgcttttgt 3990841 ccatcactca aatttttgat cagaactttt ccatcaatat tatccagatt aagtaaatat 3990901 gcgattttat ctatcatttt tgcatcaaat tttttactca aaaagtgtaa taaaaagtcc 3990961 ttagaaacat cattaggtat attcgacgag ctggatatta aagaaacatt ttgacgaata 3991021 tctctgccga ttcttttgct attattcaac aaaaagtctt tagcaagctg tgatttaccg 3991081 actccatttt ttccgacaac gtgattaatt ttcccgctcg aaaaatgcaa gtcggtgtcc 3991141 tgaagtaacg ttttgccttt cacttttaaa gtgtaattcg ctatattcat atacatactc 3991201 ctaggaaata tttgcataat aataaaatgt tctgccttgt gatttgttac taatgtctaa 3991261 gcttttgagg tacctctttc gtttccgatc cggaagcgaa agaaatgttt ttagatggct 3991321 aatttggaga tcttttactc tagtttacaa tatataatat ccaatgtaca actgaattca 3991381 ctgcaaggcc aatccctata atttgaatcg taagaactaa ccaatgattt gtcttaaaac 3991441 ggctatattc atctaagctc agaaaagcta aaagaatttt gtaaccatca gaattcaata 3991501 ttgggattaa gttccacaat aaagtagacg agaaaagcat aaatgccata gttaatgctt 3991561 cactggaaaa tgtaaattga tttattaatt ctaatgtatt tattaaaaga taattgataa 3991621 acaagccaaa taaatgaacg attatctttt catttcttga tagcatgtag gtttcattca 3991681 attggacata aaaagcagga aatacataaa aattcagttt gaatcccact ttatcaaagt 3991741 ttttcccgaa aaattttaag gaataaatat gtcccagttc atgaagcact atattcatta 3991801 taaaataaat aactataatt atccacattt tccagccgta aaatactgag gacaatccat 3991861 tttgcaattt tattaaatga atataattta atatgaacat gagagccgta aaggataaga 3991921 acagataaaa aaactttggt gatactttct ctttatacat tttaaaacgt aataattgtt 3991981 tatctgacag agaatttaaa ctatttttat agtattctcc gctttttttg tcttttataa 3992041 atacgttgtt ttgcacaagc acttcatatt tttcatcttc atactttaaa attttcatta 3992101 tagtattttt ccatataagg atagaagtag tttatttttt ctgcagagtt gaataaggaa 3992161 ccacaaactc cacaaataga ggaaaattca taaggaatgt caaattcctc tattttgtta 3992221 ttttctttta aaatattcaa aaaccatttg aatccttctt ttctaagaat aaataatagc 3992281 aaattggaat ttaacttttc cacggttctt tcgaaacttt ggttatattc ttcccttagg 3992341 gttattttcg tttcaaaaat agcaggggaa caacatggat aaatttctcc atcatgatga 3992401 tatacaatgt catatccggg acaatgtaag gaatcttcat cttcaagact gtaaaattta 3992461 tgtatgtttt cttgcttaat tctagtttta gcagcgccaa ctgatatcat tggaaatttt 3992521 gttatcttta cacctaagat tgaatccccc aattcctcta aaatgtggtt ggacattttg 3992581 tctttggtaa ctgccatatt aagagaaata tcgatatcag ggtatttcct gctatgttct 3992641 aatatgtttt taatactgga agacttgaca aatggagcat ggtactcatc ataacttata 3992701 gtcagtgcta tcacatttaa agaattcata tcatgaaagt actcctggac ctttttcttg 3992761 ctcaaacccc aaaatccatt agagatcaac gttatttgtt tttcatatgg tttaatgatt 3992821 tccattagtt cttttaaaaa tttataatct aaaaaaactt ccccacctgt aaaagaaatc 3992881 acttgaatgg ttttgttttt tgcaaattca gttactaact ctcttatgta ttctttttcc 3992941 atcctggttg ttgaagttgg tgaactagaa aaacaacaat ggtcacagga tgcattacac 3993001 cttgaatcta aattgattga tactgtttta ttatacatga aatatccccc aacaaatggt 3993061 aaaggagagt tagactctcc tttgtacccc tctaattaat gaccacttcc aagaatccag 3993121 cgattttctt ttgattttac aaaataccaa agatcattca cttttgctaa cttttgtgat 3993181 tcatctaata gacccttaaa ttctaagttt ttcacagtct cattgttagt gatttccttt 3993241 ttcatattat ccctcctcct tttctaatat aaaccaatta ttctatatca ttcaatacat 3993301 gtcaatatat tgtacctaaa aaatctgaaa aatgtcacta ttcttggtat ataaagccta 3993361 tagtcctcta gcccctctaa gctataccga atgaaaggcc atagtttgat ttaaagcttc 3993421 gtaatgaaaa gtaaaacatc aatattgact acactagtta agggatatac agattttaag 3993481 tggaagaaat gaggcaaaca atcttaccct aaaccaacct gtactgaaaa gctgttttaa 3993541 gctcttgctt accccatttg gcacctcttt ctctcgtttt aattgtctct aaaagcagtt 3993601 atgcggtact atcatataaa ggtccaatgt ttaaaaataa tgtcatactt ttaaattcac 3993661 cttatcatgc acatgctcat aaagaggggt ttattctaaa aaggggatgg acggttttgg 3993721 aaagcaagta cctagatcta ctcgcacaaa aatacgattg tgaagaaaaa gtggtaacag 3993781 aaatcatcaa tttgaaagcg atattgaacc tgccaaaagg caccgagcat tttgtcagtg 3993841 atctgcacgg agagtatcag gcattccagc acgtgttgcg caatggttca ggacgagtca 3993901 aagagaagat acgcgacatc ttcagcggtg tcatttacga tagagaaatt gatgaattag 3993961 cagcattggt ctattatccg gaagacaaac tgaaattaat caaacatgac tttgatgcga 3994021 aagaagcgtt aaacgagtgg tataaagaaa cgattcatcg aatgattaag ctcgtttcat 3994081 attgctcctc taagtatacc cgctccaaat tacgcaaagc actgcctgcc caatttgctt 3994141 atattacgga ggagctgtta tacaaaacag aacaagctgg caacaaggag caatattact 3994201 ccgaaatcat tgatcagatc attgaacttg gccaagccga taagctgatc accggccttg 3994261 cttacagcgt tcagcgattg gtggtcgacc atctgcatgt ggtcggcgat atttatgacc 3994321 gcggcccgca gccggataga attatggaag aactgatcaa ctatcattct gtcgatattc 3994381 agtggggaaa tcacgatgtc ctttggatcg gcgcctattc cggttccaaa gtgtgcctgg 3994441 ccaatattat ccgcatctgt gcccgctacg acaacctgga tattattgag gacgtgtacg 3994501 gcatcaacct gagaccgctg ctgaacctgg ccgaaaaata ttatgatgat aatccagcgt 3994561 tccgtccaaa agcagacgaa aacaggccag aggatgagat taagcaaatc acaaaaatcc 3994621 atcaagcgat tgccatgatc caattcaagc ttgagagccc gattatcaag agacggccga 3994681 actttaatat ggaagagcgg ctgttattag agaaaataga ctatgacaaa aatgaaatca 3994741 cgctgaacgg aaaaacatat caactggaaa acacctgctt tgcgacgatt aatccggagc 3994801 agccagatca gctattagaa gaagaagcag aagtcataga caagctgcta ttctctgtcc 3994861 agcattccga aaagctgggc cgccatatga attttatgat gaaaaaaggc agcctttatt 3994921 taaaatataa cggcaacctg ttgattcacg gctgtattcc agttgatgaa aacggcaata 3994981 tggaaacgat gatgattgag gataaaccgt atgcgggccg tgagctgctc gatgtatttg 3995041 aacgattctt gcgggaagcc tttgcccacc cggaagaaac cgatgacctg gcgacagata 3995101 tggcttggta tttatggaca ggcgaatact cctccctctt cggaaaacgc gccatgacga 3995161 catttgagcg ctatttcatc aaagagaagg aaacgcataa agagaagaaa aacccgtatt 3995221 attatttacg agaagacgag gcaacctgcc gaaacatcct ggcagaattc ggcctcaatc 3995281 cagatcacgg ccatatcatc aacggccata cacctgtaaa agaaatcgaa ggagaagacc 3995341 caatcaaagc aaacggaaaa atgatcgtca tcgacggcgg cttctccaaa gcctaccaat 3995401 ccacaacagg catcgccggc tacacgctgc tatacaactc ctacggcatg cagctcgtcg 3995461 cccataaaca cttcaattcc aaggcagaag tcctaagcac cggaaccgac gtcttaacgg 3995521 tcaaacgatt agtggacaaa gagcttgagc ggaagaaagt gaaggaaacg aatgtgggtg 3995581 aggaattgtt gcaggaagtt gcgattttag agagtttgcg ggagtatcgg tatatgaagt 3995641 gaggggtgtg gggttcaggg atggtgatat gctgctcccc taaaagtaga tagatgaatt 3995701 ttagaaaatc tgtttgcctt ggggagtttt ttcatggctg gacaattata ctacaaggaa 3995761 gaaatactaa tacttataga atgtaattgg gtaatgattc ggagaaagag gttgcgaaat 3995821 aatatggtat tacactgaaa caattatcaa tggagaacat gcacgatata gccgttctat 3995881 attctccctc tattatggca ctcattagta gacataaccg taaaaaaatg cactcaaaaa 3995941 aagtccattc tatataactc tcgctagggt ggaccttttt caacattcaa agtactagat 3996001 tttttctagt gaaagaataa gaaaagacat aagttctatt ttatcactct gttataggtt 3996061 aagttattac ggtgtttcat tatatactga atttaaacac ccttgacatt atgggaattt 3996121 ttaaaacagg ttaaaaggaa gttctataag aactccctag tttaatatta tttggtcaaa 3996181 atctaaaacc aaaaaatcta tttttatctt cattgtttct atctaatttt gcaacaatca 3996241 tacctttcga ctctaattct tgaaggtcat ctaataataa ttcattttta tttattgtta 3996301 caaaatattg tccgatccta ttctctaaca gacttgaatt gatatgtttt aataatgtac 3996361 cttttacatg aggatcagga ttagaataag atccgtcatg aattaaaata ttcaaactac 3996421 acttatttat acacctgtat aaaaaccaag taagatcaaa tatatttatc ttcatatgga 3996481 gtctaccatg tgaacgttca tccggtatag aacaagaaat tttgatcctt cctgtagttg 3996541 attgttttgc gttacttatt ctattatcat attcaaaatc taaaaatcca tgttggttgt 3996601 atgtaacatc cattagatta ttaaaaagct tctttaactc actaactata gcgctataag 3996661 attgaaactc atcataatac attgaattaa ctcttaatat ttcatgttga agttcattaa 3996721 tcttatcaaa aatatggttt tttttatcgt agtcactaat tctcaatctt acttccgcta 3996781 actctatttc tttccttctt tgttcttcca tcacaatgga aatatcctca atgaaattgt 3996841 tactctttaa aattctggca cttgattcca gttgttctgt taatccttgc tttttgatat 3996901 taagtttttt taaatcggct tgtattttaa caattttatc tttaaaataa ctccctctac 3996961 tttctaccat gaaattatag aactcttgga ctttattata attctgtttt acttcctctg 3997021 gaaaaaaacc tacaatatct tcatagaatt tttctatatt ttctaattct ttaatcttag 3997081 ttactttttt atttaaatca tctatatttc tttgatattg tttacaaata tgttcatttt 3997141 caaatatttc attttgtatt ttattaagtt cacttttaat ttctgagtac ctatttgtat 3997201 cattattata tttattggca gtcttagttt gatagataac tctattgtaa tcctctatct 3997261 catttattaa ttcatcttcc ttaactttta aatcgccaat gttaatattc attgattcaa 3997321 tcaattttat ttcactattt aatttttcaa tcttatcccg aaaaaccttt atgttttttt 3997381 ctgtatgagt tggtaaagta aaaagatagt taagtaattt atattgtttt aaccctcccc 3997441 tattcggtaa aactatatca ttaaaccctg tcttttcgtc tcttataata tactccctta 3997501 acgccgcaaa agttatatcc tctttctcac cctttaaaat ttccttttca ataaattttt 3997561 tatatacact tatactaact tttttccatt cctccaaatt aaaagttaaa gaagtatcat 3997621 gtaatgtata accatgttta ggagaattaa aagatctagc aaggaatact tgatttccat 3997681 caatttccac attcaaaaca ataaaaacgt ttttattgag aagaatttca tttgtcgtat 3997741 aaaaatttga tatagtcttc cctagtaaaa aggagatgca ttcaatcatc gttgacttac 3997801 ctacaccatt agtctcttca tgatcttctc tcttttcacc aagtattata tttactccta 3997861 cagcattaaa tttatactct ttcaaaattt cttgggaatt gcaaacaaaa agatttttta 3997921 taatcataac aatcactaac tctccgttct gctaatcata ttttgattaa aagaaacttt 3997981 acctaatgaa tataaaaaag ttaacgataa atacagtatc cgttcaatat tcaaatttat 3998041 tataatacct tgactcttag cataatcaag aaaaagttga tcaatatgtt tttccttctc 3998101 taacagttca taaagtatct ttgatgagta taaaatattt tcttccacag cattatattt 3998161 agttaataaa aaatgattca tttctggcct ctccgccttt tcctttttta aaggagaatt 3998221 attcactaga ggaataagat catttccaat ttgaatgttt ttaaactcat tttctaataa 3998281 aacataagag tatttgagaa tattttcagc tgtttcaatt ttaagatcaa tcattcttaa 3998341 cacttctttt gttatcatta aaaatctcac attcataaat gcaccaacat gttaaaatct 3998401 taatgtattt tttcgttaaa gcctttgaat atggtaaaac tgaatgacat tctagataaa 3998461 tctcattaac aatttttaca aatatctcat ctccattatt atattgatta tgaaactcta 3998521 gatatttgtc tactatcgtc tcagcaatca attccttttt atcagcactt acatacgaag 3998581 tggaatccat tatatggttt atcacaccaa aatactcaga ataactatcg aatttccgtt 3998641 taaaagtttc cccacttttc atatcataaa attttttatc taaaccaatt tgattatcaa 3998701 aattactagt aaatgtttta taactttctc tatactcatg aaaatctata ataaagctct 3998761 taaactcatc ttcatcaatt ttatcatcgt tatcttctat ttctttttca ataaggctct 3998821 ctaatctatt aatcttataa tttaacttcc cttcctgtag tctccttcct ccttggttgt 3998881 tttttgacca gtatttatat tcggtattcc aaatgtagta tgttacttct gtctcgccat 3998941 tatctaaatt cacatccacc gaaataaatt ctggagtagc atactcatcc tttataatgg 3999001 ctccacttac taattctaag aatggatttt catttgtatt tgcagtaata ttaaatgaag 3999061 aatcatgtac atgtcctgcc aaatatagat caataaagta atcatcaaaa tgtgccttta 3999121 ttgattctct ttcggaagat tcaatacaac ctaacgtatg gtgcccaata gctatattta 3999181 ataccttgcc cttatttttc tctttgttca tcttccttat tgctttatat aatttcatct 3999241 gtgcagttaa taacgttcct tcttcacctt ttttatctga taacagacat gtatttattg 3999301 ataaaacatt atacttctcc gattgataca aaaaatgcaa atcttcttcc ggatatttaa 3999361 cacccataaa atcttcataa aaatcgaaaa atttcctttg accttccact aatatatttg 3999421 tagctttttg atctagttta tccaacattt ctgaggggtt aggagatttc ataatactat 3999481 caatcaaaag tgtcctcgtc atgtctctag atatatcgtg atttcctggc actaagtgta 3999541 cgttattctt acttaatccc atacttttaa taattccatt aagatattct ttaacatctt 3999601 cgttatacac atcacctttg tgtgctatat ctccagttaa taataaaaaa tcaaaatctg 3999661 actctcttct taaaacttct ataaaatcta ataatttatc tctcattaca atagtgtcat 3999721 aattttgaaa ctgaaaatgc aaatcagaaa tttgtaaaaa acgtaccttc aatacaaaca 3999781 tcctctcata agtatattta tcccctatat atttctagaa aactttttat tctatatcat 3999841 ctttactctt taatatatta agactctttc cacaccatca aataaattat aacctaaaca 3999901 taactcttta ctcattttag tattgtattt aagtcaaaca ttgcattggt tgctgaaata 3999961 ttatattcat tgaattattc cattaaatag cttttagttg aactttagtc tttctgtaat 4000021 ggtggagatg ctcttactta tgataaggct ccccacgatt aatccgaaaa gcccgataaa 4000081 tctgctccac taaaataagc cgcatcaact gatgaggaaa tgtcatcttc gagaacgata 4000141 gcttctcgtc cgctcgcttc atcaccgtgt cactcaatcc gagtgatccg ccgatgacga 4000201 aggtgacttt gctttttcca taagtagcca gcttatctat tgtatcggct agttcttcgg 4000261 atgttttcat ttttccttcg atggcgaggg cgatgacgtg ggcgtcgggg ctgattttgg 4000321 ataggatgcg gtcgccttct ttgtctttta tgattttcat gtcctggtcg cttaggtttt 4000381 ccggcgcttt ttcgtccggg agttcgatga tgtcgatttt tgcgtaggcc gaaagtcgtt 4000441 tggtgtattc ttcaatgcct tgcttgaggt atttttcttt tagttttccg attgtcacaa 4000501 tattgatatt cacaggtcat ccccacttta aaaacaagtt attcatatat gttgtccaca 4000561 attgtggata tcttttctgt attttgtgta agatcattcg ttccccacta tatatactgc 4000621 ggggtctcca cataattcac aggctgtgga taaactgtta gtatgttcga tttttctgat 4000681 ttcgggcggc agctcgtggt cgtctatgta catatccagc accgtttcga tgtgttcttc 4000741 acaagaataa tacgcttgtt tcatgttcaa atcctccgat gttttcttcc atttttacaa 4000801 atgttctctt ctcaatataa cctatttatt cacatgttag tagtgcttcg ggctgagttt 4000861 tatccacaat tcgacaaaca agctgttgat gactctattt cgctcgtgtg ttagtttgga 4000921 tgtaaccgat gtgtggggag gtctgcattt gcgctttaga tgggtttggc tttttgtgat 4000981 tatgttgctg cttgctgagt gtcagccatc ttattgggtg ttggagaagg atcgaatcgg 4001041 tgaaggcagt ccagacttag aaatatacgc taattatctc caaatgcatg atgacgtgaa 4001101 aggatatcaa gtcttcacca tatcagaagg caaaaaaatg gtcgtcgtgt ctctcggaag 4001161 cagcgagaaa gataagaagc ttgaagtgtc ggacgtcaaa ttctcatcta aagaaacgat 4001221 tgtaactgtg gagcgaaaac ctgctcctac ggcaaatgag aaaaaccctt ttattttgat 4001281 tggactggac aaaattgaag gggatttaat tgttcaagac gaaacaggag atcgctttga 4001341 agaaacggat taccagcaat aaagccggcg ttctgagaac gtccggcttt ttcttttact 4001401 tcaatgtccc atgcgggtcg atgacgaatt ttttggctgc gcctttgtcg aagtcgctgt 4001461 agccttttgg cgcgtcgtcc agagaaataa cggtggcatt gacggctttt gcgatctgcg 4001521 ctctgccgct caggatcgct ttcatcaaat tgcggttgta tgtcatggcg ggcgtttgtc 4001581 cggtgacgaa ggtgtgggct ttggcccagc cgagtccgaa gcggattttt aatgagcctg 4001641 ttttggcgtc cgcatccttt gcaccgggat cttcggtcac gtataagcct ggaatgccaa 4001701 ggctgcctcc gacctgggtg acgtccatga ttgagttcag cacggcggct ggcgcttctc 4001761 cttgattgcc gtgcccagat gcttcaaagc cgacacagtc cactgcagca tcaacggttg 4001821 gttcacctag tatttgttca atttgctcgc cgaggcggtc gtgtttttgc acgttgaccg 4001881 tttcacagcc gaagcttctg gcctgtgcca gcctgtcttc gttcagatcg ccgacaatca 4001941 cggtagaggc gcctaggagc tgagcggagt gtgcagctgc caagccgaca ggacccgctc 4002001 cagcgatata aacggttgaa cctgtttgca cgcccgctgt ataagctcca tggaagccgg 4002061 tcggaaaaat gtcggacagc atggtcaaat cgagaatctt ttctagcgcc tgttctttat 4002121 cagggaatac caaaagctga aaatcagcgt atggcaccat gacatattca gactggccgc 4002181 cgacccagcc gcccatatcg acgtagccgt aagccgatcc cggccggtcc ggattgacat 4002241 tcaggcacac atgcgttttc tgcgttttgc acatcacaca gcgtccgcag gcaatattga 4002301 aaggaacgga tacgatatct ccttttttga taaattcaac atcacgcccc gtttcaatga 4002361 cttctcccgt aatttcatgc ccgagcacca agccttctgg cgccgttgtg cggcctctga 4002421 ccatatgctg gtcgcttccg caaatgttgg ttgtaatgac tttgagaata accccatgct 4002481 cacattttcg attcacattc gccttcggga cgccgggccc gtccctcaag attaactccg 4002541 gataaccgat atcctccacc gctacagtcc ctttgccttt gtacacaacc gctttgtttc 4002601 ctgtcaacgc cattcctccc attcatgtgt ttggactctc cgtccttgaa catgacttcg 4002661 gttcggcatg actctttccc tttttcacga ctgttttttc tgtattctta caacaacaaa 4002721 tatgccaaga aagcatccaa taatggttcc gccgatgtct aagaagtcga ctttacatcc 4002781 atttaacaag aacacagtaa tggccgaaac caggcagatc ataactgcca gaagaataac 4002841 ccgatttgtc tgcatgtaat tcctcctttg gattcgtttc taaaccatac ccaaaatcct 4002901 ctgcaaactt cggttcaaca aaaaaagaga cttcacacca gtctcttcat aaacagagat 4002961 cactcaaaaa atttcctgag aaataatgtg gcaacactcg ttactaacgc aattgccgta 4003021 tacataacaa cccaaaatat gaatgagcta ttccccgaag ctaacgtaac taacaatatc 4003081 aagctcgtga taagaacgat gagcggtgcc acccaaaatc ttttaaataa aaaatgaccc 4003141 gctataccaa atacacctgc gacgatcgga aaaccaaaaa cgataaataa aacggcgatg 4003201 gctcccatac taccctcctt gccttaaaac ctcttcatca cctcaacatc atacagcttc 4003261 aaatgactct tcggcgtcac gacatccttt accttcccaa tctctttttc tttcattttc 4003321 tttccggttt tcaggctgta ctgttcaatg taggcaggct tgtgatacgt gtatgtgaag 4003381 aaatagaggc tgctgccttt ttgggtgatt tctttgaatt cggctttcat tttgtccggg 4003441 gaaagggtga agacgatgct tgtttttcct gtcttggcat cgattttgtg tacctttccg 4003501 aagccgtcaa tgaaatacag gttcccgtca taagggaaaa agctgttttt aaagctgaag 4003561 ggcatggagc tgtatatcgt ttgttcgtcg tttttgtatt cggcgatatc gtgcagctct 4003621 acttcgccgc tttttttgtt gatcttgacc atttgataga gatcgtgggc tttttggccg 4003681 cgaaccataa catacacagc ttggtcgtcc acggcaagtt gggattcgac tgaggctcct 4003741 tcccggtact gccattccgt tatgctgaga taggtaagct tcttctgatc tgcttgaatc 4003801 tgaaggagct gatagccttt tccgtcatct gtcgggacga gtgcgtaaat ggcgccatca 4003861 tggaaaccgg aggctcggat gtagtagggg atgacgtctt ttttccactc tccgtccatt 4003921 tggcggtaca gctctgagcg gtatccgtct ccctttttgt cgtagccgga gttgtataag 4003981 gtgtaaaagc cgtccgtgtt ttgcagaaag cccgcgctgt cgcctgtgtg ctgataggtt 4004041 cttttatggg agcgcaggcc gtttttgatc gtataaatcg tgtttttgtc ctccagcatc 4004101 acgctgtcac cgtgaacctt tgctgagccc agctcaaggc ccttcatctg aaaggaagac 4004161 agcgtcccgt catggctgat aaacagggcg tagcttttcc cgccgccaaa tgcatcttga 4004221 tccgcagagg atgagaaata cagcaggact tctttgtcat ccaggaaatc gggatttctg 4004281 agatcctgct gactcacggt tttatggctt ttgagaggag aaatgaagac aaatagtgcg 4004341 attcctgcga gaatcagcat ggcgatggta atcatccact ttttcatagc cttctcctta 4004401 gtaaatggtc ataatggttg tcgtataaga agaactagtg atgtcgcgcg gatacacgcc 4004461 taagcctccg ttgctgtcta tatcaatccc tgctttcagc aaaaaggcag accataggag 4004521 ctttgaacag tttttggcgc cgtcatggcc ggtatttctg ttattgacga agttaaatga 4004581 gtatgggtcg ccgacttttg ataccgccca gtcggcagca gctgtttttt gagatgagga 4004641 tacgctgacg gtttgcacaa tggagttgtc ttccacgtct ctggcattat acgcgatctg 4004701 cctgacgccg tcgctcggga cagattcaac aattttgtca gcggcggagt acatgccgac 4004761 atggccgtga ttgtagtagg ctgtgtagga gttcgtgtaa tagatattgc ctttcgcgct 4004821 tgtcgggagt tttttcgtgc cggacgagcc gcccatgata gacatgccgc tttccttggc 4004881 gagccggtcc ccctctgctt tatcagccgt gatctcctta tagaactgtt ttaggataac 4004941 gtcctgcttt acgtgctgct gtttggcaat ctggctggca gatttcatga tttcttccgg 4005001 tgtcgtgcct ggctgcagtg cggcgatttc ttcagcataa tttgtggtct ttacggcttt 4005061 ggcgggagta acaaacaggc cgccgcacat tgtgagcgct accaaaaaca tcgacactcg 4005121 tttcttcaac ttcattacat ctcctctttt cttgtgagtg taggaaaggt aatttcctca 4005181 cccacattat attaggaaaa taaggaaagt aactaggtta tttacagaat ttttagaaat 4005241 cgtttacaga aaaaggcctt tatcaggccc ttttcgttaa agcttcttgc tcatcactac 4005301 gtctgtttct tgaaatccgg tttgctcata tagctttcga gccgtctgat tatgggcaaa 4005361 gacatgaagg gacagcttgc ggattcccat actgcgtgcc gcttgatcta atgccgccaa 4005421 tgcttgcttt gcgtagccct ttccccgata cggttcatat aacccgaaat cataaataaa 4005481 cgcttcctgc tgcggatgct ccggttcagc atgtatccag agccagccaa cgatatcctt 4005541 ttcattcagc ttgaggctcc acaaatggtg atggggtgtt tcgagccctc tcggaagcag 4005601 atcagtaaac acctgcttag acaaaagctg ggcatcttca ggcagccatg ttcccgcttt 4005661 taccttttct tccgcgtaat gctttgttgt gtacgtgaga taagaccgaa attcttctgt 4005721 ctgcataggg gttagcataa ttgtcatatc atctctcctt catatattga ctagaggatt 4005781 ttacataaaa tagaaagagg tgttactatc agaataagca actgagattg ataagtcact 4005841 agagaaagga gtttcacatg aataagatcg cacccgcaga aatcgctagc atgctcaacg 4005901 attggtacct tgccatcaag aaacatgaag ttgaagaatc ctcccgttta tttgaagaag 4005961 tgaagccttt attggatgac atggaagagg atcaggaggt gcttgcctac ttctccttat 4006021 tggaactgcg ccacaaggtt ttgcttcacg aggcgagagg acagggcttt cagcatgagg 4006081 agccttctca tatgaatgct acgtctgaca tgctgaaata ttactttttt ctgtttgaag 4006141 gcatgtatga ggcctataaa aataattatg acattgccat tgggctgtat aaagatgcag 4006201 agcagtatct cgacaacatt cccgatccga ttgaaaaagc cgaatttcac ctgaaggtcg 4006261 gtaagctcta ttataagctg ggacaaaata ttgtgtccct caatcataca cggcaagcag 4006321 tcaaaacatt cagagaagag acagattata aaaagaagct ggcttcagcc ctgattacca 4006381 tgtcaggcaa ttttacagag atgagccagt ttgaagaagc tgaggcttat ttggacgaag 4006441 caattcggat cacgagtgaa ttagaggatc atttttttga agcccagctt ttgcataact 4006501 tcggccttct acatgcgcaa agcggcaaat cagaagaagc ggtttcgaaa ttagaggagg 4006561 ctctacagaa cgatgagtat gcccgctccg cctattatta tcattctgcc tacttgctga 4006621 tacgagagct gtttaagatc aaaaagaaag aacaggcctt atcttattac caagacgtga 4006681 aggaaaaatt gactgctgag ccgaatagaa tatgtgaggc aaaaatagac attttatatg 4006741 ccatttatgc agaagggggt catgcggaaa cgtttcactt atgcaaacaa catatggatg 4006801 acttgttgtc cgagaaagag tatgacagtg taagagaact ttccattttg gctggcgaac 4006861 ggtataggga acttgagctt tacaaagaag ctgcccactt tttttatgaa gcattacaga 4006921 ttgaagaact gattaaacga acggaggtta tataaatgaa aagatttctg attggcgcag 4006981 gcgtcgcagc ggtgatttta tcaggttggt ttattgcgga ccatcaaacc cactcacagg 4007041 aaatgaaagt cgctgagaaa atgattggat aaatgaaaaa cccccgcggg atgcgggggt 4007101 tcaatttaac gaaagaatcc taaaacggtt tgtagtttta ggattctttc atcttttcag 4007161 cgtgattgaa aacccttgaa gtctaggaag aacgagcatt ggagcgcagc gaatgtttgg 4007221 aattcgtgag caccgaagcg caggcctgac aacgaatgcg agggtttgtc gacacgctga 4007281 aacccccgcg ggtgcggggg ttttcttatt acagcagctt cttccctaac agggattcta 4007341 cgagctctac tgctgttttg cccgttttgt ttttgtgatc aaggatcggg ttaacctcaa 4007401 cgaattcggc tgaggtaatg atgcctgcgt catacagcat ttccatagcc aaatggctct 4007461 cccggtagct gatgccgccg acgacagggg ttccgacacc cggtgcgtcg ttcggatcaa 4007521 gtccgtccag atcaaggctc agatggacgc catcacatgc tgataaataa tcaagggttt 4007581 cttcaatgac ctttgtcatg ccaagacgat cgatttcgtg cattgtgtac accttcatgc 4007641 cgctttcctt aatgtacttg cgctcccctt catcaagtga ccgggcgcca atgatgacga 4007701 cgttttccgg tttgatttta ggcgcgtagc cttcaaggtt aaccagtgac tcgtggccaa 4007761 tgcctaggct gaccgcgagc ggcatgccgt gaatattgcc cgatggtgaa gtttcaagtg 4007821 tattcaaatc gccgtgcgcg tcataccaga tgacgccgag attatcgtaa tgcttcgctg 4007881 tgcctgcaag cgtgccgatc gcaatactgt ggtcaccgcc caggacaagc gggaattttt 4007941 tctcttcaat gactttgttg accttttgcg cgagtttttc atttcccgcc aaaacggaat 4008001 tcaggttttt cagttcctcg tcatttttga ttttttcgcg attgatcgga atgtcaccga 4008061 gatcttcaac cgtatacccc atgtctgaca gcctctcgat cagatgagcg taccggatgg 4008121 cactcgggcc catatccact ccgcgtcgtg cttgtcctaa atccattggc attccaataa 4008181 ccgaaatcgt tttatccatc tgtgattcca cctcaacatt taagataatg tcctatgcgg 4008241 gttataacaa agatgacttg cggacaacgt ttttaaagct ctagctgacg atttgcctgc 4008301 tggcgttttt taatgacgac atgataaatg atgtagcaaa tgatcataaa cggtacgccg 4008361 caatacagcg cgatacgctg ctccggatca aatgcaagac tgatgagcac gaccgtattt 4008421 aacgttaggc cgatcagcgg aagcaccggg tacagcggtg ttttaaattt caaatcttct 4008481 atcttcccgc cctcacggat atatttgcgt ctgaacatga tttgggaaag cgagatcgta 4008541 atccagccga cctgcgcgct catgcccgcc aaagataaca gtaccatata tacggtttca 4008601 gcctgcgcaa actttgtcag aagtgatagg caggccacag ccatcgttac gattaacgag 4008661 tacatcggta caccgcgctg atttgttttg ccaagcgctt tgaaggcttg tccttcattc 4008721 gccatcgcgt acagaatacg tgttgatgcg tataaacctg agttcgcaac agataacagt 4008781 gcgattaaaa taacaaagtt catgatatca gctgcatatg ggattccgat ttgctcaaat 4008841 acggcaacaa atggactttc cacgacaccc gcctgtttcc acggaatcat gccggcaatg 4008901 acaatgattg aaagcacaaa gaacacaagc gttctccata ctgtctgttt gatggaccgc 4008961 ggaatcgttt tttcagggtc ttcactttct ccggctgcaa ccccgatcag ctcagtcccc 4009021 tgaaacgcaa agttcacagt aatcatcgta atcagcattg cctttatgcc gttcggaaat 4009081 aacccgtctt cataaaaatg tgtcaaaaac ggcgcctgct ctccgccctt cagatcaatc 4009141 aggccaaaca tggcagctcc gccgagaata ataaataaaa ggataatcaa aattttaatg 4009201 cctgagaacc agaattcaga ttccgcaaag gcttttgtgg tgatcgcatt taaaataaac 4009261 atcagtgccg caaagaccag acaccagatc cacacgtcta tatgcggaaa ccagcgttgc 4009321 atcagctgcc ccgctgataa aaattcaatg gcgcatgtaa ccgcccagcc gagccagtac 4009381 agccagccga acgcaaaccc gaaggccggg ctgataaatt tcgtggcata ggtctggaag 4009441 gaccccgaca caggaaaggc gactgccagc tctcctaagc agagcatggt caaaaacatg 4009501 ataaagccgc ccactaaata ggacagaacc gcgccgagcg gtcccgcttg gttaatggta 4009561 aacccggttc caaggaagaa accggttccg atcactccgc ccaatgaaat catgaacaaa 4009621 tggcgtgatt tcattgtccg ctggagctga tttccgttat cttggtttgt attcacattc 4009681 tgcacccctt cagcaacttg tattggatct aagctggaac atctgcatgg tgctatccca 4009741 gtttgctgtc caaagagtct ctatctattt aatataaaat tcacttcttc tcataaagat 4009801 acattatact aaaatactgt agctgagcaa atagggagtg ctgatttttc tgttgtaaat 4009861 ttatacaaac gaagtgaata tcccgccatg gtgcggattt atgcgtttcg cagcacgtgc 4009921 ttaattttct ctatcgccca atccaagtcc tctttggaaa tgattaatgg cggtgcaaaa 4009981 cgaatgactg tatcatgcgt ttccttgcat aaaagtccct cttccttcaa acgctcacaa 4010041 tacggacgtg ccgcttcagt caattccaca ccgataaaca gccctctgcc gcggacttct 4010101 ttaatgacag ggctgtcaat actctcaagc tcgcttttaa agtattcacc aagttcaaga 4010161 gaacgatccg ccagcttttc atcctccagc acttctaatg aagcgataga cactgcacat 4010221 gcaagcgggt ttccaccaaa tgttgagccg tgtgagccag ggttaaacac gcctaggatc 4010281 tcgcggtccg ccgcaatgca agagatcggg aacacaccgc cgccaagcgc tttgcccaag 4010341 atatacatat ccggaacaat gccgtcccag tcacaggcaa acgtcttgcc tgtacgtccg 4010401 agacccgtct gaatttcatc cgcaataaac aagacattct cttccttaca aatcgccgcc 4010461 gcttcctgta aaaatccttc aggcggaatc acaatgcccg cttcgccttg aatcggttca 4010521 aacaagaatg ccgctgtatt cggcgtaatg gcctgtcgaa gcgcttccac atcgccgtaa 4010581 ggaatgagtt tgattcctgg aagcatcggg ccgaatcctc gtttatattc ctcttcagaa 4010641 gaaagagata ccgccagcat cgtgcggccg tggaagttcc cgacacatgc gataatttcc 4010701 gcttgattgt cagctacgcc cttcacttca tacgcccagc gtctcgccgc tttcaccgcg 4010761 gattcaaccg cttcggctcc tgtattcatc ggcagaatca tctctttgcc tgtcagttta 4010821 gctgtttttt cgtaaaacgg cccaagctga tcgttatgaa acgcgcgtga cgtgagggtg 4010881 attttatcag cctgatcctt taatgcctga atgattttcg ggtgtctgtg cccctggttt 4010941 accgcagagt aagcactcag catatccata tattcattgc cttccgggtc ctttacccaa 4011001 gcacccagcg cttcagaaat aacaatcggg agcgggtgat aattgttggc tccgtaatga 4011061 gacgtctgat caataatttc tttggattta gataaagctg tcatatttga attccccctt 4011121 gttttctgtt tcaacatgtt atcctgcttt ccctttatat aaatgcaagt tctgtgccaa 4011181 atcaagaatt cgtgtgtttt ctacaatttt cgaggacaag gtgcaaaaac attctgatat 4011241 ttcgagcgaa aatttcagca agtgcaaaat tcttttgcat atcctctccg tttttttata 4011301 aaatagaagc aatattaaga aaataattga gggaggttca tacagtggtc aaagacagcg 4011361 aattcctcac attggttttt cagagtattt tagatgaaat cgatgttggc ctgcacgtgg 4011421 tagacgagca tggaaacaca atcgtttata acaataaaat gatgcagatt gaagatatgg 4011481 agaagcatga cgtcttgaat aaaaacctga tggatgtgtt tatgttttca aagcagcagg 4011541 acagcacact ggtacaggct cttcaggaag gcaagacgat taaaaacgtc aaacagagct 4011601 atttcaataa taaaggccag gaaattacga cgatcaatca tacatatccc atcgtccaag 4011661 acggcaaaat caggggcgcc gttgaaattg ccaaggatgt gacaaagctg gaacggctga 4011721 tcagggagaa tatgaacaaa aaaggcagca caacctatac gtttgacagt attctcggca 4011781 ccagtccggc cattcaagac gtcatcgaaa acgccaagcg ggcaacccgt acgtcatcat 4011841 ctgtccttct agcaggcgaa accggcacgg gaaaagaact gttcgcgcaa agtatccata 4011901 atggaagcga tcgttctggc ggcccgttta tttcgcaaaa ctgcgcggca ctgccagaca 4011961 gccttgtgga aagcattttg tttgggacga aaaaaggcgc gtttaccggc gctgtcgacc 4012021 agcccggcct gtttgaacaa gcccacggcg gcacactgct gttagatgaa atcaactcgc 4012081 tgaatctcag ccttcaggcg aagctgctgc gcgcccttca agaacggaaa atcaggcgca 4012141 tcggttcaac aaaggataca ccgattgacg tacgtattat tgccacgatg aatgaagacc 4012201 caattgatgc aattgcaggc gaacgaatgc ggaaggactt gtattacagg ctgagtgtcg 4012261 tcacactgat catcccgccg cttcgggaac gaaaagaaga cattttgctt ctcgcgtcgg 4012321 agttcatcca gaaaaacaac catctgttcc aaatgaatgt tgaacacatc agcgatgacg 4012381 tgaagcaatt tttcctttct tatgactggc cgggaaatat tcgcgagctt gagcatatga 4012441 tcgaaggcgc aatgaatttc atgacggacg agcaaacgat tacggcttcc catctgccct 4012501 atcaataccg catgaaaatc aagccggctg acatcccaga gccggaaaca ccaagacacc 4012561 agccagccgc ggacttaaaa gaaaaaatgg aaagcttcga aaaatatgtg atagagaacg 4012621 tgttaagaaa acacggccat aacatctcga aagctgctca ggagcttggc atcagcagac 4012681 aaagcctcca atatcggctg aagaaatttt ctcactcgtc taacgaataa tccggagcag 4012741 gaagcctgat cagaaaaaca gtgcctctgc cgatttcact tttcacttca atcgtcccat 4012801 tgtgattgtc gataatcgat ttcgttatgg caaggcctaa tcccgaacct ccatatttcc 4012861 gggagcggga tgggtctgcc ttgtaaaacc ggtcaaacac taaaaaacgt cacttcttat 4012921 gcattgaaga aagaaaatgg cacctatgtg tatcacagcc agcaaccaca cggtacaaac 4012981 cattaaagtc catgcaaata acggaagtat ttgcagctaa ctgccatttg ctgtttcacg 4013041 tgtaacatcc atcttgtatt tttcttcata ttcgatatat cctttttcaa ctgaacgggc 4013101 gtgacccctg ttcagttttt tttgcatatc aaaacagcct ggcaacgatg ccagactgct 4013161 tttattaact gcctaattgg tctgcggagg acagcttgat atcaacagat ttttcttttc 4013221 cgccgcgata aaacttcacc ttcacccggt caccgacttt tttctgataa agccgttttc 4013281 gcaggtcaac aatatcattt actttgtatc cgtcaaattc cgtgatgaca tccagttcct 4013341 tcagccccgc ttttccggca ggtgaaaagg cgtctacacc catcacaacc gctccattgg 4013401 tgacgttctt aggaagcttt aatgtttcat cccaatgata gcttgcgatg tcacttagcg 4013461 atttcatctc aatgccaagg aacgggcgtt tgacctttcc gtatctctct aaatcctcta 4013521 tcacagggat cacgagctta gacggaatgg acaggccaat cccttcaacc gctgactcgg 4013581 caattttcat tgaattgatg ccaatgacct tcccatccat atttaacaaa gcgccgccgc 4013641 tgttcccagg gttaatggcc gcatctgttt gcaggacttc agcgttccag tcaggctgtc 4013701 catcaccgtt tgaatctact gggatcgccc tctccgtacc cgagatgacg ccttgtgtga 4013761 cagagcctgc aaactcaagg cctaacgggt tcccgatcgc aataaccggc tccccagact 4013821 tcactttatc tgaatttccg aaatcagcga ctgctttaat cttatcgctt ttcacccgta 4013881 aaacggcaag gtccatcagc tggtcgctgc cgacaagatc agctgataca cgtgagccgt 4013941 ctttcaagct gatttcaatt tgggaagcgc cttcgatgac atgatggttg gtcacgacat 4014001 aagcggaatg gtcatttttc ttatagatga cgccagagcc gctcccagcc tcgccgctct 4014061 ctccccaaat atctgatttt tggatgttca caacaccgac aacggcgggc gacatattgc 4014121 tgacaatctt ggtgacggca ttgttgacac tgacattcac cgtcctgatt gattcccggc 4014181 cattgttgtt ttgctgctga tctaaggcgc ctgtatccag cccttcattt gaaaggtacg 4014241 gcatgataaa cgccattaat acggcaccga caatcacgcc aatcagactc gaaagaaaat 4014301 atcctttttt gcttctcttt ggctgttcag gagtagtatg ttcttcctca cgttcgtaat 4014361 ccaccatatt ccatcctttc caagaacgtt aatatggtta tattgtgggt tagaaactcc 4014421 tagaatagtc atgatttaca tagaaaaatt atacagcgca aagcggagtg gccttcttcg 4014481 gatcggtgtc gtataagtca aatgtctcac ccgtcacaaa tcctttagaa gccaatgtct 4014541 gctgcacaga cattcttgcc agctccttca tgttgttgtc ctggctcaaa tgcgccaggt 4014601 aaatacgaga cgtctcatcg ccaatgacat ccgtcatcgc caaggcagca tcttcatttg 4014661 acacgtgccc gacgtcactt aaaatccgcc gcttaatgct ccatgggtat cttcccattt 4014721 gcagcatacc gacatcgtga ttgctttcaa acacaaatac attcgctgaa cggataatgc 4014781 ctttcatccg gtcgctgaca tatcccgtat ctgtcattaa cgcgagcttt cggccgctat 4014841 aatggaatac ataaaacatc ggttccgccg catcgtggga aacgccaaac gattcaacat 4014901 caagtccgcc gaacgacttc accgtctcca ttggaaatac aaacttttga tcggtgtcaa 4014961 ttttgccgat ttgattctcc atcgctttcc aagtcttctc attcgcatag atcggaagct 4015021 tgtactttct ggcgacgaca ccaaggccct taatatggtc actatgctca tgcgtcacaa 4015081 aaatgccgtc tacatcatcc agcttacgcc cgatctgcgc catcagccca tccatggctt 4015141 ttccgctcaa accggcgtcc actaaaaatg cgtgatcctc tgtttcgagg taaaacgcat 4015201 ttcccgtact cccgctcgca agtacgctaa attgcaagct catgtttgtc tcactccatt 4015261 attttcattg atctgtatct aaaatcgtac tctccaaagc attcacagta aaatactctt 4015321 gtactgtctt tttctcaccg ttcacttttt tctcgtactc gaccgtaatt ctccataccg 4015381 gcgccagcac ctgcgtactt gtcagcggat attgtgctac atagccgaat ttacagctct 4015441 tcacagtgct gtattctttt aattgatttt gatagtacaa tagctcaacc gcatccattt 4015501 cagtaattaa gctttctttc tggatttgct tgaaggtctc aagcgtagtc tggtcgtatg 4015561 acacaacctc gtttttaccg tttaagtgca gcaccacttg cccgatcata ttagagggat 4015621 tgtcggtctt ttggtaaata taatgacctt cgtacgtttg gaagaaaata atttctttct 4015681 tcgatttatc aaccttccaa agcttatatt tttcgccatc ttgaattttc gaagaaacaa 4015741 gtgcctgagc atcgtcctcg atatccttct ttgatagtgc gattggattt gcaaacttca 4015801 ttttcaggct cgttacttta tgatcatcac taggcatgtc catcaaaggc ttttgatcct 4015861 tcagcgcctc aatttcctcc ttggagaaag acttttgatt tgccgtgatc cgatagcctt 4015921 ctgttgcttc cttattcaag ccttcatacg tgatatgatc ggccttcatg tcatgctcga 4015981 catcattttt aatgacttca tattctttgc cggtagcctg ccatttttga aaaaactgat 4016041 agcctaagaa aatatctaaa atgaggaagg caacgatgaa gattgatttt gtcttattcc 4016101 actccactgt tagccccctc cttcctcaat aaatcctttg taatcggcac aatttttcca 4016161 tttactttca tcgcccaaac cggttccagt tcaacgagag gatcatcgtt ggttgatgtt 4016221 gataccaatt gataagcaag gaagatctga tcaattttgt ccgtatcata agcggtttgt 4016281 ttcgaaagca gcatcttcac ttcgctgccg cccatgagct ctgtttcact tgttttaatc 4016341 ggattcgttc cgagactgta attcggccgc ttatagctga gaatatcatc attcgcccat 4016401 tgcaccgtaa tcgccgatgt cgccccgaaa ggtttggcgg tgctgttaat gaccgggatc 4016461 tgatccataa aaatatagaa gctcaactgc tggctgtcat tgatattgaa aaattgatag 4016521 tgatccgtcc agcttccggt atcctcaagg tatttttggc tctttttgat taattcacct 4016581 gtttgatagg atgtgctctg caccaaattg cgctgctgaa attgcacctg tctctggctt 4016641 agattcacat ctaaccggct gatcccatct gtcagcacat ttctgttgtt gtaattcgaa 4016701 tcttctctta caatgctcgg atcactaaac aaagcctgct taaaggtatt tgttttaatc 4016761 gattctgtga caaattcttt tttgtccatc gtaagcggtt tgttcggcag caagaactct 4016821 ttctttgagc caatggagaa caaactgaac gccggcatat ttgattgcct gtttttcaag 4016881 tcgttcataa tgttccggta gtttgctgat tcaaccgtca cttcaagaat gagctgcttg 4016941 ctgtatgaca ccaaatagat tttcttgttc gcttttgttt cattgaacgg gatcagaata 4017001 tggtcaaacg aactgtattc aaacgactga ttagaccatt taaacagcgt ttggaaaata 4017061 tcaatcggga tcgtatcgct gaattgcaag tcaagcttgg cttcagaacc gcctattcca 4017121 taaaaccagc ttttgaatcc agccttgtca tactgatccg aaatatcttt aattcctttc 4017181 acatcccaat gcggcaagtc agaccaaatt tcttcataga gggcattgtc atccactttg 4017241 taatgagcgc cgtcatcatg gataaacatg tcccttggcc ttaccgtttc agacagcttt 4017301 tgggtggttt tttcgatttt atgtttcaca cgaacagtag actctgttga ggatgagcct 4017361 tcagaaaagt ttggctggaa cgtccatatc ccccatgtaa aaacaagact gatgacgacg 4017421 agtaccgtaa gtaatatcgt ttttatattt tcacgcttca tcccaatcat cctcttgttc 4017481 ctctttatat ggaagagtaa atgtaatcgt cgtgcctttt ccttctatgc tgtccgccca 4017541 aatatctcca ccgtgcgcct gtaccatttc cttggcaatc gccaatccca gaccggtgcc 4017601 gccaagcttt ctcgttctcg ctttatccac cctgtagaag cggtcaaaga ctttttcgac 4017661 atcttttttc ggaatgccga tcccttcatc cttcacgctg atatagagaa gttcttcctc 4017721 ttcattgaca tcaatcgaga acgtgacatg tccgccttcc ggtgaatatt ttaaagcgtt 4017781 agaaataata ttatcgagca cctgcgttat tttatcctgg tcaatctcga catacagatc 4017841 tctgtccggc agattgcgga taaactccac atgctgctct tttgtcattt caaaacggtc 4017901 aataataagt gacataaacc ggacaatctg aatccattcc cggttaaatt gataatcttt 4017961 actgtcaaat ttcgacagct gaagcagatc attgacaagc cggatcatac gctctgtttc 4018021 attttgcgtc accattaaga agcgcggagc aatgtcttta ttttcccacg cgccttcagc 4018081 taacgcttct aaatagctgc gcattgtcgt aagcggcgtc cgcagctcat gtgatacatt 4018141 cgcaacgaat tctctgcgtt cctgatccat tttctcttgt tcggttacat cgtaaatgac 4018201 agcgattaaa ccatcaattt tgccgtgttc cctttgaatc acagagaaat tcacgcgaag 4018261 caccgttaat tcatcatcgc gctcaatttc aagcagcata gaatcctgct gttccactaa 4018321 atcttcaaaa gtataattct cttgaagccc cagcaaactc gtaatcggca tttctaaggc 4018381 tgtttcacgt gaaacgttca acagttccag cgccgggctg tttaagagaa taatcgctcc 4018441 gtttcggttt gtggcgataa cgccgtctgt catataagca atgacagagg ctagctttct 4018501 gcgttctcct tcagtcatcg cctgggcatc ttcaagctct ctcgttaagt ggttaaacgt 4018561 tgtggccagc tgcccaattt catcatgtcc atacttttta accttcctcg agaaattccc 4018621 tttcgcaagc tccatcgcct gctttcgcat atctgaaagc gggtgggtaa tggttcttgc 4018681 cagaaaaata ccgagaagag ccgtcaaaac aagtgccaaa cctgtgccgg acgccagtat 4018741 cgtgttgatc gtcttcattt gattaaagac atcttccata ctcgcgacaa cgtagatcgc 4018801 gcccacaacc tcttggtttt cagtcatgac gggcttcgcg gaaataagaa ctctgatttt 4018861 gcttttcggg tcataatatt ttcttaaata cgactgtttg gtagaaaaga ttcttttgaa 4018921 aatcagatcg gtcgtttgtt tcccagccac ttcctcaccg tacggctttg aagaaccgac 4018981 cacttcatag cttttatcta caaagctaat ttcccgaacc tcatcacttt tcgtgaagtc 4019041 attcaaaata cggctgacgt catcctttat gacggtactg tcgttatcgc tcttatattc 4019101 ttgttcgata taataagaaa ggttgtcgat tcgctgattc agcgattgtt cataagagct 4019161 gatcagcgac ttctctacct gattgacaaa atacacacca atgatttgca tggcaatgat 4019221 aatcaaaagc acataaatca aggtaatctt aaattggatc gaccgaaaaa aaccaacctt 4019281 attcatatgg gcattagtcc tgttctgggt ttctcaagta ataacctaca ccacggcgtg 4019341 tgacgatcca atttggatgg ctcgggttgt cctcgatttt ttcacgaagc cggcggactg 4019401 ttacgtcaac cgttctgaca tcgccgaagt aatcatagcc ccaaacggtt tgaagcaaat 4019461 gttcacgggt catcacttgt ccgatatgtt ttgctaaata atgaagcaat tcgaactcac 4019521 gatgagtcaa ttcgattgtt tcgtctcgtt ttgatacaac gtacgcgtca gggaagatga 4019581 cgagagagcc gatatgaatc tcgttagagg aaggctcttc ctccgcaggc gctgttgtca 4019641 gctggcggcg caggttcgct tttacacgcg ccaagagctc gcgtgtgctg aatggttttg 4019701 tgacatagtc atcagcaccg atttcaagcc cgataacctt gtcaatttct gaatccttag 4019761 ccgtcagcat aatgattggc atatcgtatt tctttctgac ttcgcggcat acttcaacgc 4019821 cgtctttatt tgggagcata atatctaaaa gaattaaatc aggctgaagc tcttctacca 4019881 tttcaacggc ttcgtttccg tcgtgggcac agtgcacttc atagccttct tttcttaagt 4019941 taaattccaa tatatctgca atcggttttt catcatctac tacaaggatc tttttatcca 4020001 tcattttgat tttcctcctg ccgaatgact tcatttcatc tatataacat tcgtttcatc 4020061 acttatggcc catgtaaaga atgggtcctt gtctattata acggtttaag gtcaaaagat 4020121 aaaaaaaata aaggtttaga aaaaaaacac atgtttcacc tttatcgcca gttgtttatc 4020181 tattgtcatg ctggtcaact ttttttaaaa aagataactt tattgaaacc tcccctcacc 4020241 ggagtgcgtc tttatcaatg acgtcttctt ctttgaaccg gccgcagggc cggttctccc 4020301 tttttcttct attataacac tcctcatgtt tgcctttttc ctaaaagaaa aaacgcacct 4020361 acgattgcag atgcgtttgg taagtggctc gggacggaat cgaaccgccg acacacggat 4020421 tttcagtccg ttgctctacc aactgagcta ccgagccaaa tgttttattt ttctctacta 4020481 agtaaagtaa aatggcggtc cggacgggac tcgaacccgc gacctcctgc gtgacaggca 4020541 ggcattctaa ccaactgaac taccggacct tacagtaatt gcccggagag ctgtcgtgtc 4020601 agctctcaca gacaaataag gaatttagca ataacgctaa agtaaatcaa tgacccgtac 4020661 gggattcgaa cccgtgttac cgccgtgaaa gggcggtgtc ttaaccgctt gaccaacggg 4020721 ccttcacgaa atggtgagcc atgaaggact cgaaccttcg accctctgat taaaagtcag 4020781 atgctctacc aactgagcta atggctctta aagatgtcgg aatttctata gagcaaacga 4020841 cttaaatcta gttctcatct tgtactctat tgaagcagtt tccgtaacaa cgagatttat 4020901 aatatcacga acaaatagaa gtggcaataa cttttttggt tttttttcat atttttttct 4020961 cagaccaact tatatgcggc tttcaaacaa aaacaagccc cttaaatagg ggcttgcaga 4021021 catattctat ttagttcgca cggtacacac tgcgaaggac atttgtttgt gagcggtctg 4021081 gaccgacaga gaaaatagaa agcggaatgc ctgtcagctg agacacacgc tcaagataat 4021141 ggcgcgcatt ttccggaagc tcgctcaagc tcttcgcacc tgtaatatcc tcagtccagc 4021201 ccggcatttc ttcatatacc ggctcacatt cagcaagtgc cttaagactt gctgggaatt 4021261 cttcaatgat ttcgcctttg tagcggtacg ccacacagat tttcaacgtt tcaattcctg 4021321 ctaggacgtc aattgagttc agagaaagat ctgtaattcc gctcacacgg cgggcgtggc 4021381 ggacaacaac gctgtcaaac cagccgacac ggcgcgggcg gcctgttgtt gttccatatt 4021441 cgcgtccgac ttcacggatt tgatcgccga tttcatcttt cagctcagtc ggaaaaggac 4021501 cgtcgccgac acgagtcgta tatgcttttg atacaccgac aacgtgcttg attttggtcg 4021561 ggccgacacc agaaccgatc gtgacaccgc cggcaaccgg gttagatgac gtaacaaacg 4021621 ggtatgttcc ttggtcgata tcgagcataa ccccttgtgc gccttcaaat aatacacggc 4021681 gcccttcatc aagagcatcg tttaagacaa cagatgtatc gcaaacatac tttttaatct 4021741 gctgtccgta ctcataatat tcgtctaaga tatcctcaag tttaaaccct tctgtctcgt 4021801 acattttctc gagaagacgg tttttttctt caagattgcg ctcaagcttt tccgcaaacg 4021861 cgtcacggtc taacagatcc gcgatgcgaa ttccgatgcg ggctgcttta tccatgtaag 4021921 cagggccgat tccttttttc gttgtgccga tcttgttagc ccctttacgc tcttcttcca 4021981 cttcatccaa tttcaaatga tacggcagaa tgacgtgagc tctgttgctg attctcaggt 4022041 tatctgtact cacgttgcgc tcatgaagat acgcaagctc tgtgactaat gctttcggat 4022101 ctacaaccat tccgtttccg attacacacg ttttatcctt atagaaaatt ccagacggga 4022161 ttaagtgaag cttatatgtg attccgtcaa acttgattgt atgccctgcg ttatttccgc 4022221 cttgataacg ggcgatcact tctgcatttt ctgataggaa atctgtaatt ttaccttttc 4022281 cttcatcgcc ccattgcgta cctactacaa ctactgaaga catgtccgtg cacctccgtt 4022341 aacctttcaa aacgattcta ttcaaacaaa tcaagtttat cagtgaagaa acagaaagtc 4022401 aattgtaaat ccgaacatta atttattgta aatctatatt cgttcgcttc cattcgtttt 4022461 ataagcgttt tctcactgct ttgtcataaa aagcttgcga aactttcatc ctttagcata 4022521 agaaagaatc acttgcctga tatccctttt gaattcataa aaacgatccg ccagccgtcc 4022581 gggtcctcta tcgtcacgcc cccattgctc cagtacgggt tctctgattc gacctcttga 4022641 tagcccatgt gctttagctt tgaagtgatc gctgccagtt caactgcatt cggcacataa 4022701 aaaacaagaa ggctgtcggg atggggaacg ggggcagtgc ttcccccttc atactgggtg 4022761 aattccaaat gataatcggc atgaggaagg ccgaacatga caccgtcata cccgttatgc 4022821 tgtgaaaatt ctcctattcg tttcaaacac agtccctctt cgtaaaaacg aataatctca 4022881 tcaagctggc ccgtaggacg cgcaattcgg atttgtgctg cttgaaaaga cgaaaaacgt 4022941 tttcccatat tgttaccatc tcctttttgc accattttat taaaacgctt tcaatttttc 4023001 atccgctgag cgaacgtcat ttcttccatc tttcgaatga aaaaaacccc aagagcagct 4023061 cttggggctt atgcgccggg cggaacgcct gcgtcatcaa aacgccgttc caggttgacg 4023121 aatttgttgt attcttttac gaacgcaaga gacacggttc ctaccgggcc gttacgctgt 4023181 ttggcgataa taatttcgat aatattttta ttctcggttt ctttgtcata gtagtcatca 4023241 cgataaagga acgcgacaat atccgcgtcc tgctcgatac ttcctgattc ccggatatca 4023301 gacatcatcg gacgtttatc ctgacgctgc tcaacacccc tggaaagctg agaaagcgcg 4023361 ataacaggga cttgcagctc cctcgcaatc gacttcagtt cacgggaaat ttcagatact 4023421 tcctgctgac ggttgtcctt tgaacgaccg cttccctgaa tcaattgcag gtaatcgatc 4023481 aaaatcatgc ccagcccgct ttcctgcttc aagcggcggc acttggcacg gatttcactc 4023541 actcgaatac ccggtgtatc atcgatgtaa atcccgctgt tcgataggct tcccattgcc 4023601 atcgtcagct tgccccaatc ctcttcggtc aggttacctg tacggagatt ctgggcattg 4023661 atatttccct cggcacagag catacgcata acgagctgct cggcacccat ctcaagactg 4023721 aaaatcgcta cgctctcatc ggtcttcgtc gccacgtttt gtgcgatgtt cagggcaaag 4023781 gctgttttcc ctactgaagg acgggcagcc acaatgatca agtcgttgcg ctggaaaccc 4023841 gcagtcatcc ggtcaagctc cgtaaaccct gttggaattc ccgtgatatc accttttcga 4023901 ttgtgaagct gttcgatatt atcataggtc tggacaagga cgtccttaat attttggaag 4023961 gcactcgtgt ttttgcgctg tgccacttcc ataatcgttt tttccgcttc actgagtaaa 4024021 tcctcgacct catcctcacg ggtatacccg tcttgagcaa tcgttgtcgc agttctgatt 4024081 aatcggcgaa gaatcgattt ttcctcaacg attttcgcgt aatattctat gttagccgct 4024141 gtcggcaccg agtttgcgat atctgtcaaa tatgaaatac cgcctacttc ttccagcagg 4024201 tctgtgttcg caagctctga tgtaactgtc accagatcaa ccggttcacc tcggtcaccg 4024261 agcaccagca tcgcattata gattttttgg tgggacattc tatagaaatc atctggaatc 4024321 aatacttctg aagccagtgt taaagcagac ggctgtaaaa aaatagcgcc taacacggct 4024381 tgttcggctt ctatattttg cggaggaagc cggtcattca gaaggtctgt catgctaagc 4024441 accgtcctct cattaaaaaa tctccaacct ccattctacc atttctacag aaaaaaaata 4024501 gaaaaattgt ctgtttcctg tttttttcag ttagcagatt ggatcgtttc ggacagtaac 4024561 aaggcgggaa aaatgcaata aaacataagg gaggaatgaa agatgataaa gaaatatgcg 4024621 attacaccta atgttgatgc ggacggctgg tttattgagg tggagaatgt agcgccgaca 4024681 gctttgtata cgtctaaaga cgccgctatt gaaaaggcca aacaggtggc taaggaaaac 4024741 agtccgtcta agcttgtaat ttatgaccag tttaaaaatg tggaagaaga acactcattt 4024801 taatgaatga aagccttcgc tgcagcgagg gttttttagc ggttatcggt ttatttcatc 4024861 cattggatgc ctatgtgcat catcaaatct gccgcttttt gatacagatc ccactccccg 4024921 atcgaagcaa atttccccat cagctcctga agctttaacc tcattgctat atattcttcg 4024981 aaagtgacag ctttttcagt gtctatttgg tgttccttca gcatttgttt taataaggat 4025041 aacggtgcgt gcataagaac cctccttacc tcttttataa cggtcatttt ccgattgctc 4025101 tattcctttg tgacatcttc ttacatttca catctgattc ttgtacaatg gacagaagag 4025161 aggagggatc ttttgtgaga cctttgcaaa tttctgccga aactgcacaa aagcttgcag 4025221 agtccttgaa tctgccgctt gaacagatca tgcatatgcc tcagcatatt ctgcttgcca 4025281 aaatggctga actgcaaaaa gaggacaaat catagccttc attcacatac ttgcttacct 4025341 gtttcgggat aatatcatgt atatgttaga aaagaggagt aactgctttg ccacatccac 4025401 ataataaaaa aatccaatca ttttggctga tcaccggcat tatctttatc gcctttaact 4025461 tacggcccgc gatcacttca gtcggtccgg tcatcagctc tatccgggca gagctgcaca 4025521 tgtccaatgg ggcagccggt tttttgaccg cactgccgct gctttcgttt gcagttcttt 4025581 ctccgcttgc acctaagctt ggacagcgcc tcggtaatga gcgaacttta tggctaggtc 4025641 tcgtgatact gctgatcggt gttctgactc gttctaccgg ctatactgcc gctttgtttt 4025701 tcggaacagc acttatcggc gtcgggattg cgattggtaa cgtacttttg ccaagcttaa 4025761 tcaaacataa ataccctgaa aagccaggga tcatgatcag cctgtatacg acatcaatga 4025821 atatattcgc agctttagca tcgggtgtca gcgttccttt agcgacccag atgaatggcg 4025881 gatggaaaca agcctttctc ttatggggcg ggctggcttt acttgcattg ctaatctgga 4025941 tacctcagct gcgccatcga gatacggcaa accagacaat gaagctgcaa tccagttcca 4026001 tttgggcttc caaaatggca tggtatgtca ccatctttat gggcctgcaa tcgtttttat 4026061 tttacagcag catcgcttgg tttcctgaaa ttctccgttc acacgggatt gatacggcaa 4026121 cagccggatg gatggtatca ctcatgcaat ttgcgagtct gccttccact tttctgacgc 4026181 cagttttagc tgaccgtgtg aaacagcagc gcggtatcgt tgcggcgctg gcctcagttt 4026241 atctgatcgg cctttgcgga ttattagcgg gcggaagcca tacattgctt gccatctgga 4026301 tgatcattat cggtatcgga caaggctcca gcattagtct ggcccttact ttgattggtc 4026361 tccgcagtga aaatgcccaa caggccgctg cgctgtcagg catgtctcag tcattcggct 4026421 acctgctggc agcagtcggg ccaatctttg tcggctatct ctttgaccag acgcattctt 4026481 ggacgatgcc gattgtgctt ctcattgctg ccctgatcgt aatgggagca gccggacagg 4026541 gagccggacg agatcgatac attttccagt cagaaaaaca aagaaattca gcataaagcg 4026601 gggaagatat ctccgctttt ttctttgaat atttatggtt tattcataag tttttcatat 4026661 ttgtttttta caatgagaca ccataaagag gtgaaaaacg atgaaaacca aacgattcga 4026721 cgcagccctt attcttattt tgctagcagc agcttttttg aatacgtatc acatttggca 4026781 ggatgataca gcaaaccagt actatttggc ggctgtaaaa agcatgacgc aaagcttcca 4026841 taactttttt tatgcgtcat ttgacccttc tggatttgtg acagtagata agcctcctgt 4026901 cgtgttatgg attcaaacga ttttcgcact gattttcggt gttcacacgt ggagtgtcat 4026961 cattccccag gctcttgccg gagttggatc tgtcttcctt ctctacagaa tggttaagcc 4027021 gacttttgga gttggagcgg cccgcattgc cgcacttgtc atggcactga cccctatcgc 4027081 agtagctgtc agccggacaa acaatatcga cagcatgctt gtttttacct tattgctcgg 4027141 ttcaacttgt ctgcttaggg cagtaaaaca aggcaagctg gtttggctgc tgacggcatt 4027201 tgccctgatt gggctcgcct ttaatatgaa gatgatgcaa gcgtttatgg tattgcctgc 4027261 atttgtgtta ttctacctga ttgcatctcg ggtttctctg aagaaaaaaa tcgggtccct 4027321 gcttctgtct cttgtccttc tgacaggcct ttcactctca tgggcgattg cagtggattc 4027381 agcctcttcc tcaagccggc cttatgtagg aagcagccag actaactcag tgctagaact 4027441 ggcctttggc tacaacggca cagagcgtct gtttgggcaa actacgggcc ttgcaaaggg 4027501 tgatatgaat gctgctggcg gagggaacat gcagaatcaa gacaacatgc aagcgccaaa 4027561 tggcaacggt tcatcttttt ctcagaacgg taatcaatca ttcggaaacc attcacaggc 4027621 gcctcagccg cctaacggac aaaccggcgc tctcaatgga ggcggaggca cacctcccac 4027681 aggtggcaac ggacctggaa atggagggcc tggcggcgga ggcggaaaaa gcgtgaatat 4027741 gttcggcacc ggtgatcctg gaccgcttcg tctcttccaa tcagcacttt ccggccaaat 4027801 cagctggatg cttccattct cattgatcgg attactgggc gcaatcatca gctggtaccg 4027861 tgatcgccgc ggacatgctg ctaaaatgaa agaaacgcta ttctgggcgg cttggcttgt 4027921 tcccgtggct ggtttcttca gcatcgcagg attcttccac cagtattatt tgattatgct 4027981 ggcaccgccg attgccgccc tttctggtat cggatggtat acgatgcacc gcttatacaa 4028041 aaataataaa gactggtcca gctatcttct gccggcagcc gtcttgatca cagccgtgtt 4028101 tcaggtgtat attctgagcg cttatacaag ccaaatcggc agtgtatgga tgtatgtcct 4028161 ggggctctta ggactgggca tcacccttgc acttctgatg cttaaacgca gccatccgtt 4028221 cagtaagctg ctgaccatca tcagcttgtg cgttctgctt ctcacaccag tttactggtc 4028281 agcaacgccg cttctatacg gtggcaacag cgtccttcct gaatccggcc cgcagctcaa 4028341 aggctcagca aacggcggga acatgttctc ttcagaggtc gacagcgggc tcctgtccta 4028401 tctgagaaaa cacaataccg gcgaagagta tttatttgct actttgacaa ccgtaacagc 4028461 tgcgccatac atcatttacg aaaatgaatc tgttatggca atgggcgggt ttaacggcac 4028521 ggatcccatt ctgactgtgt cggaactgaa aaaactgatc aaagaaggca aagtgaaata 4028581 cttccttctg tcagaaaaca actcaggcaa cagcgaactt gtttcctgga ttaagaaaaa 4028641 cggaaaagaa ataacatctg acgagtacag cggttcctcc agcagcacaa acagcgtgca 4028701 gggaatgcga agaggacctg gcggagaaag ccagcaaact ctttatctcg tggaataaaa 4028761 aaagaggctt ggatgaatcc aagcctcttt tctattaagc ttcttctttt acatgtacct 4028821 ttaacacagc ctgcacttca ggatgcagct tcacaggcac gtttgtatat cctaatgcac 4028881 gaatgccgtc cggcagttca agcttccgct tatctacttt aatgttatgg tctttttgga 4028941 gctgttcagt gatttgcttg cttgtcactg aaccaaataa acggccgccc tcacctgatt 4029001 ttgcgctaag ctcaacagtc agtttttcta atgtctcttt caagctctta gcctgctcaa 4029061 gctcagcaat ggcttctttt ttctctttct gcttttgtcc gtttaacgcg ctgatgtttg 4029121 acgcgttcgc ttcaaccgcg aggccttttt taattagaaa gttatgcgca taaccgtctg 4029181 ctacgttttt gacttcgcct ttttttcctt ttccttttac atcttgtaag aaaataacct 4029241 tcatctctgt acgcctccct caaaatactc atctatggcg tgcttcagcc gttccagcgc 4029301 ttcagaaact gaaatgccgg acaactgagt cgccgcattt gttaaatgcc ctccgccttc 4029361 cagggcctcc atgatgatct gaacatttac ctcgccaagc gaccgagcac tgatacaaac 4029421 cgtttgttca tcccgtctcg ccaccgcaaa tgaagcctca acctcactca tcgatagcag 4029481 cgaatcggca gcctgcgcaa tcagcacttg atcgaagtat tcctcttcat tttcaggaag 4029541 agaagcaatc gcaatgttat ctttatagag gaccgtatgc tggatcagct tcgcccgttt 4029601 aatataggaa tcaacggttt ctttcagaaa cttctgcacc agcaccgtgt cggcgccttt 4029661 tgcccttaaa taagaagccg catcgaaagt ccgcgagccc gtgcggagag aaaagctctt 4029721 tgtatccact attataccag ctaatagggc tgttgcttca atcatattga tttttaagcg 4029781 cttcggctga tattcaagca gctctgtcac caattccgct gtggaagaag cgtatggttc 4029841 catataaacg agcagcggat ctctgataaa ctcctcacct cttcggtgat ggtcgatgac 4029901 cacgatatgt tcaattttat tgaccagccg ttcctccatg acgagtgacg gcttatgtgt 4029961 atcaacgatc acaagcagtg tgtcatcatt ggaaatctcc attgcttctt caggcgtaat 4030021 aaatcttgac cacagttctt catatttttt gatttcccca atcaaacgct gcacacttga 4030081 tccgatttgg tttgggtcaa tcacgataaa accatctttg ttatttgcct gagccacctt 4030141 taaaatcccg atcgctgcgc cgatagaatc catgtcgggg aatttatgcc ccatgataat 4030201 cacattgctg ctttcggtga cgatttcctt taaggcgtga gaaatcacgc gggcccgcac 4030261 ccttgttcgt ttctccattg ggtttgtttt accgccgtaa aacttcacct tgccgtttgg 4030321 cagcttaatg gctacctggt ctccgccgcg tcccagtgct aagtccaagc tggattgcgc 4030381 caaatcgcca agttctttca gggaagagac tgaagccccg acaccgacgc ttaacgtcag 4030441 cgctacaccg tcaaacgagg ttttttcccg cacttcatca agaatcgaaa acttcgaatt 4030501 ttcgagttca gttaagatat gttcattaag tacagcaata aagcgttctg aagacgtcct 4030561 tttcaagaag atcccgtact cctgcgccca agcgttcagc aaagatgtca cctggctgtt 4030621 catcgtgctt ctcgtctggt catccaatcc ttgtgtcaca tcatcatagt tatcaaggaa 4030681 aatatatgcc aggacggttc tttcgttttc atatagcttt tcaatctgga tttgttctgt 4030741 tacatcaaag aaatataaga gacgctcatc ccgtttgatg acaaccctaa acttgcggtc 4030801 attcaatgta accgtttccg attccacctc ttgtttgata agcggcacta ccgattcaca 4030861 agtatcgtaa agtgatctcc ccactaaagt gctttcatta aaacaagagg aaagaaacgg 4030921 atttgcccat tctatataat attggtcatt aaaaagcatg attccaatcg gcatttccat 4030981 caatgcctct tcaccgactt ttttcaacct gtaggacaac gtagaaatat aagcatcaat 4031041 ctcttgtcga ataagagaat cagcacgctt aataaaaaac aaaataactg ccagcagcag 4031101 cacttcgacg gttcctaata tccagttaaa ataaaagctg atgaggattg taataattga 4031161 cagagcaatc aatgcataga tgggataccg aaacagcggt ttttcataaa agcttggcat 4031221 ttctatcact ccccaccatg tgagtaaaac tcatgttcac ttcaccttat tccttatatg 4031281 aaagcccata tctaaaacgc ctaaaatgcg aatggccgcc atgaagaccg gatgcacaaa 4031341 cccaagtatg acagcaatca cagccgcagc ctttggatat tgtttcttat ggcaatagaa 4031401 aaagataaat gataaacctt ggatgaaaat cagaaacccg agtataaact ccccatttaa 4031461 agcgatagag tacagcattt ggcctttttc taaaggcaaa aatgaaagca tgacaataat 4031521 caaatacagt actacaacac tttgcggaaa cttcaactct ctaaaaggct ttagattagg 4031581 aatatcgggg gagaatcgcc ttaagagcgg cttagcgata aggtaactga ggaaagaaaa 4031641 aataactcct accatcacaa tagctgttgg aaaaagatat tgaacgatac ccaattgttc 4031701 ttccatcagt tttaattgct tctcaaactg cccagcattg cccgactgct tcgctacagt 4031761 ttctacaata tcaagagatt gccggtattg tgtcattgcc tcatcaatga tattgatacc 4031821 caaaaactga atgcttatca caaaatagaa gacaatacta agcatataaa taagagcgcc 4031881 cgaaataatg gcgtgcccgg gctctttcct tttgaaaaaa tgtcccatgg caatgccggc 4031941 gcaagctgac ataaaagcta caataagccc gttaaaggac ccgacaataa aaacaaccgg 4032001 aagactgaca gcgcccatcc atatccctag cttcaatcca tgtctgatcg tatacaagat 4032061 cattggcagc ggcagtgcaa ataacagaat tgttccaatc acaggaacat aaacgaccag 4032121 aagcgtaatg atcgcaaaca gactgattaa aatagcacct tccattaaag ctctcgtttg 4032181 tttcacttag tcacctcgta tcatcctgaa catacgaata gaaaagagca gcataaacga 4032241 ctgctctttt gttcatcgct gcaacatgct ttgcaccgaa tgtttttata tcatctctaa 4032301 attttacttt tatattttaa cataagtcca aatcgcaagt aaaatgacgc taatgtttca 4032361 tgtgaaacat gaaaaaggaa aagacattct ttgaaaagaa tgcccatcac aattaatgtt 4032421 tatcatccat aaagccagaa gattccttgt ttttcttttt cgtttttctg acatacataa 4032481 aaattaagat caccagtaaa agggttgttg cttgcagaac gccgctgcta aacaagaaaa 4032541 agttctttat catgtcccac attgtgtttc acctctttgt gcatgttctc aacccgtatc 4032601 ctatataagg tgaatttccc tttttaaaaa cttcaaaaca tcatgaacaa cattgagcgt 4032661 tgggcatatg ctgatatgga atctgatcga taaaggagaa ttttcacatg gatgaacgca 4032721 gaacattggc ttggcatgaa acattagaaa tgcacgagct ggttgctttt caatcaaacg 4032781 gactcattaa actgaagaaa atgataagag aagtaaaaga ccctcagctc agacagcttt 4032841 ataacgtgtc tattcagggt gttgagcaaa atttgagaga gcttcttccg ttctttccac 4032901 aggctccgca cagagaggat gaggaagaag aacgcgcaga taacccattt tacagcggtg 4032961 acctgctcgg ttttgccaaa acatctgtcc gcagctatgc catcgcaatt acagaaacag 4033021 caacacctca attaagaaac gtactggtca aacagctgaa tgctgccatc cagctgcacg 4033081 cccaagttta tcgatacatg tatcagcatg gatattatcc gtcttacaac ctttctgaac 4033141 tgttgaaaaa cgatgtcaga aacgccaaca gagccatttc aatgaaataa aacaagcagc 4033201 aaaggagttc cctttgctgc tatttctgct gatccttcac taagccgttc gaacgataag 4033261 attccagcac gtctctgttg gattctcccc attctttcat ttgcaaaaca atcggttcaa 4033321 gcgtgcgccc aaattccgtc agagagtact ctaccttggg cggcacctgg tgataaacct 4033381 cacggtgcac gatgccgtcc gcttccagct ccctcagctg gagagtaagc attctttgag 4033441 taatactcgg gcagattcgc cgaaactcat taaatcgttt cttgccatct atcatgtgat 4033501 aaaaaagaat tcctttccac tttccgccaa tgacatctag agtgaattca actggacagc 4033561 cttctttgtt cgggtatata ttcttttttt cactcattct tgaccctcca atagtacctt 4033621 ttttgatact acattacatt ttgcaactaa tctacccagt attttacaca ccttttctcc 4033681 ttagctcaaa gaaaatgctt cttattcaca tcaattttta agggtttgca tgattacacc 4033741 tgcagcaaga cgtgttaaac tatataaaga ttacactact taaaaaagga taggagctat 4033801 catggaaaag atacttattt tcggacacca aaacccagat acagatacga tttgttctgc 4033861 gattgcttat gctgatttga aaaacaaact cggcttcaat gctgagcctg tccgcctcgg 4033921 acaagtcaac ggcgaaacac aatacgcgct tgactatttc aaacaagaaa gcccgcgtct 4033981 tgttgaaaca gctgcaaacg aagtaaacgg cgttatcctg gttgaccata acgaacgcca 4034041 gcaaagcatc aaagacattg aagaggttca ggttttagag gttatcgacc atcaccgcat 4034101 cgctaacttt gaaacagctg agccgcttta ctatcgtgct gagcctgtag gctgtacggc 4034161 taccatctta aacaaaatgt acaaagagaa taacgtgaaa atcgagaaag aaattgccgg 4034221 ccttatgctg tctgcgatca tttctgattc cctgttattt aaatctccaa cttgcacgga 4034281 ccaagacgta gcagcagcaa aagagcttgc ggagatcgct ggagtagatg ctgaagaata 4034341 cggcttgaac atgttgaaag caggcgctga tctaagcaaa aaaacagtgg aagagctcat 4034401 ttctcttgat gcgaaagaat ttacactcgg cagcaagaaa gtcgaaatcg cacaagtaaa 4034461 cacagtggac attgaagatg taaaaaaacg ccaagctgaa ttagaagctg tgatctcaaa 4034521 agttgtggct gagaagaatc ttgatctgtt ccttctcgtt atcacagata tcttagaaaa 4034581 tgattcactt gctcttgcaa tcggtaacga agcagcgaaa gtggaaaaag cgttcaacgt 4034641 tacattagaa aacaacacag ccctcttaaa aggcgttgtt tcccgtaaaa aacaagtcgt 4034701 tcctgtctta acagacgcaa tggctgaata agcaaaaagc atcccgcgtc gggatgcttt 4034761 ttcttattca cccagcttct caatttgtcc catcacatca gtaatttgct ttgcgttttg 4034821 gaccaggtct gactgctcca attctttaag cgataccttg ccttcctcgg cttgtttcaa 4034881 cacatcttca gcgcttttct gcaaggtttc gttatgctcc tgaatggttc gatgaatctc 4034941 cgctgcggca tcaggcggcg ttaattcatt aaaatcagcg gcagccttct gaatcgactc 4035001 aagctgcgct tcaagttttt ctttcgcctc ggtgtcattt acagctttct cagccaattc 4035061 aggcgcttcc tctgcaaatg tcttcacctt ctccacataa ccagctgctt cactcgtata 4035121 gttcaatccg tcgttcacct gatcaagcat gccgcatccg cctgcactca aaagtcccac 4035181 tccggcaagt actgtcaaaa tgatcttcat cttcagcccc ctcatcgttt ctttttcatt 4035241 ttttctttta agatcggaat caatttctct ttcgctaacg gcagcccttt cctcaccaat 4035301 tcacgcttca gccacttttt cagcttagac attctgatgc tcctctccct ttttgataaa 4035361 aatgaaaaaa ctccaccaat ttggtgaagt tcctgaaaca aaaagacctt caccaaatca 4035421 gatttggcaa aggtctcgct aacaatgaga ttgccagcaa agccgaggac accttgtccc 4035481 gtaatgacga ctttactgtg aaagctactc ccctttggag tgttcatttt tattactttc 4035541 attctaaagc accgatctgt tccagtcaaa ttcctgccgt ttatataaaa gcgcgctgtg 4035601 gtatttaaaa tttgaatggt ttttctatca ggagatcatg ctatgacaga ggaggttttc 4035661 atcatgagtc aagagcgcgt gaaacggcct gggcatacca gatggtacat atcttcgtta 4035721 cttagcggca ttattattct taattatttt gaccgagtgg ccatctcggt agcggcccct 4035781 gcgatacaag attcgtttca ccttactgca actgaactcg gcatcgtgtt ttccatttac 4035841 acctattcct atacactgat gcagctgcct gtcggaagtt tgctggaccg ttttggggtc 4035901 gcatgggtca cgagggttgg aatgacaata tggagctttt taacgatcct tcttgctttt 4035961 ttgcaaggaa aattgctgtt gtatctgttc cggtttctca ttgggctgac gagcgcctct 4036021 gcgttccctg ctgcctctaa agcaaccgct ctctggtttc ctccaagtga gcggggattg 4036081 gcaaactcac tgttcgattc ggccgccaag ttttcaaatg taatcggcgc gccattggtc 4036141 gcctttcttg tcacaacatt tgactggcgt gtcgcttttt tgacgattgg atgcatcaat 4036201 gtgctgttta cgatcttttt ctggcagtat tatgaacagc ctgaacggca caaacgcatt 4036261 tctaaaagtg aactaaacta tattcaaaaa cacaatgcca ttacaacaga gcaaatccct 4036321 tacaaaacgg gcccgctttt aaaaaagctt ttcaccaatc gaaaagtatg gggcttaatg 4036381 atcggattta cagggtacgg gtatacattc aacctgctgc tcacctggct tccgactttc 4036441 tttaaacata catacggtat ggatctcatg tcgtccggtt tatttacggc agtgccgtgg 4036501 ctgatctcaa ccatttccgg aattgccgtc ggcggctggc tcgtcgatta ttttattaag 4036561 aaaggctatc ctaataccaa ggtgtaccga accgtaatca tagtcggaat gagctttggc 4036621 tttttctttt taggatccat tctgacgaac aatattaccg tagccattat ttgcatttcc 4036681 atcggactcg ccggaatttc cgcaaccgct ccggtcggct ggtccatctc cgcagaactc 4036741 gcgccgatcg gttccgtatc catgctgagc tccatggtga atctcgcaaa caacctgttc 4036801 ggaggcatta ttgctgcgtc actgacaggg tatttgtttg atgtgacagg ctcctttacc 4036861 ctcagctttc tggtagctgg ttttgtgctg ttgctgggat tggtttttta tgtgtttgta 4036921 ttaggggatg taaaacgaat taaactatag aacatgaaaa agagagctgc cagttggcag 4036981 ctctcccttt acatcaaaga atcggcccgt ccccatttac cttctcctcg tcctgttcct 4037041 ctatatcaag ccccgaagct agcatttcct gctctatctg ttcgagcacc tgctcgtttt 4037101 ttccttgaag accaccttca taatgaaaag catcctgtgt gccgttttcc tctattgtcg 4037161 ctaaaatatc gtggatatca ttatggtctc ctgaaatgga gccgaatccc tggttttgtt 4037221 ttttataatt cacaaaaccg ctggggaggt tgtttccgag gtttacacat gatgcgctcc 4037281 gagtagtaat tcatcagtgt atcaaaatct tcattttgga ttgccacatc acatgcagag 4037341 atgatgtctt tcaattgctg ttccaaatga attcccctaa tcatcatgat tggatatatt 4037401 atacaatgtt tgacacgtag ggatcctttt catttttgtt tttacggttt cgctggtcca 4037461 tttccgcaga gctggcgccg atcggttccg tatccatgct gagctccatg gtaaatctgg 4037521 caaacaacct gttcgaaggc attattgcgg cttcattgac ggggtatttt gtttgatgtg 4037581 acaaggctcc tttacgctca gctttctggt agccagtttt gttctgctgc ttggattggt 4037641 tttttacgtg tttgtcttag gggatgtaaa acgaattaag cgggaataaa gagtgcttgt 4037701 agagaaaacg ttgttctttc tacaagcttt ttagttttgt gctgtttttc aagatattca 4037761 gctgtcataa aaagaaaatg agctcccaca taccggctag gtatgtggcg ttcttcttca 4037821 tgttctggca tgcagctgtg aggaggattt gtttgctcac cccctgaacc tgcgatagct 4037881 aagcccgtgc agttgttttg aacctacaaa gcttcgttct attttttctt ttcttttttt 4037941 agagatttcc tgaaatagaa aagcaatctt ttctaacctt ttctttatgg ttttgccata 4038001 cataccgagt aacgactttc tggcgtttcg ttgattttgt gtaatattct caaacatatt 4038061 tcaggatttg atttatatga ccgatagtct ttgcgatcaa ttgttgagta cgtaagtgta 4038121 tgctgattca acaaatgtat ctgtattgtt cactttataa tgaaatttcc attttggaag 4038181 caaacccctg actgggtgat aacgtctatg tgcgatggca ccaaaaactt ggaggtcaaa 4038241 tagtccttta gagatgagag ttgttaagta gccggaatct agagcgacgg cttctacttg 4038301 aaaatcaaat catgcaattt agtgatccaa tcggtcaagg tagggcttgg aacagaatca 4038361 tggacttttc tggagttgca aactattaat cgtcctcatt aaatttataa taaaaatatt 4038421 ctcaattgag caaatcgccc accctttttc ctttataaca taaaatccaa tactatcaat 4038481 aaaattcttt acaggttatt acagttaaga tataatatag ttaatctttt acgtaaaagg 4038541 aggtttttat tacttgtgtt gaagttttaa ataggagtaa ctccatctcc ccattacggt 4038601 cttcatttaa tttcatcctg agttttattt agttagatat aaaaacgaaa atttcacatt 4038661 atttttaact aaccgatagt ataaaatata tattgaaagg attgtaaaat tatgaataaa 4038721 ttcctgaaga gcaatttccg tttccttctt gcggctgctt taggcatatc attacttgct 4038781 agtagtaatt ttataaaagc cagcaatgat aactataaat tccatttact tgtaccttat 4038841 ggctatggta atgcctattc aaatgatgca tttagacaga ccactcatac agataatcct 4038901 tggaaagtaa atttacagaa atcggcagaa ggtaaaggta caatcatgac attttggttg 4038961 attaacacag ggaatagtaa aattccaaaa gcttctaaaa tacataacgt aaaacaagga 4039021 agcggagctc attattatca tgcaaatagc cagggaagcc atacatatgt agccttagca 4039081 gttgaaaaca acaattacag tgcaagttct tatggtatag atggtgtatg ggatgaagaa 4039141 acttggtaaa caagaacctt ctaaaaacgt tggcaccttt tagccacgcg aaaaaattta 4039201 gaatgataat ctttttataa gattatcatt tttatttatt ctattaagaa ttgagtgaga 4039261 acatggaaag tcatatttat cgcattatca aaaataaatt aactataata atatttacta 4039321 taatcatatt aattccttgt gttgatatat cactattgtt aatgactaac acagaatacc 4039381 atcctgcata tgcgtttttc ctttctggca cttccgtagg gcatgcttca caaatgatcc 4039441 tattatggtt tcttccgctt tattttttgt tactatgtgc tgacgattct atacaagatt 4039501 ataaaacagg atatcattac attcttataa gcaaagttgg cagaaaaaaa tattgtttgg 4039561 aaaaaatatt tacctctttt atcatttcat ttttgacaat gtttttgtca ctaatattaa 4039621 actttttatt ggttcaggtt ttctttttta aaggtacatt taaaaatgac ttagaccaaa 4039681 ttaaattccc tgataacagc ctttatactt ttagtatggc ccatccttat atagcaattg 4039741 tgttattttc tattatttgt tgtattatgt ctggatttgt tggagcactt ggttcaagcc 4039801 tcagtttact ttttcgtgat aagaagtatg cctacccagc aagttttttt atttggttcg 4039861 tacttatact aaaaaacaaa tcattaatgt ttttattcca accgtttaca gaatacggtt 4039921 ataatgtact tctccctatc ctatgtttgt ctatctttat ttttctaata ataatttcta 4039981 gtattgtttt atatgaggca aaatacaatg aaaattaaaa gactactatt aattttatgt 4040041 ttactactat ttttagttac tttatggttc aaccagaacc acacttatct tggaaagaat 4040101 tctatcgcgt cattactata tatgaataat agtacattcg gatatagttc aatatttgca 4040161 tataccttgt tttatattgt cccgtttctt atgttactta gtaacttttt tcattcagaa 4040221 aacccctaca aagtaatgag gatggttaag cgtaaaaatt actacaagtc taaaattatg 4040281 gagattgggt ttgtttcttt acttttttct tcaatacata ctgttattaa tattacgtgt 4040341 acacatattt tctttagtaa aaacttgttg gtcgaagcaa actttttatc aatttgttta 4040401 ttaaacatga ttagtttagt gtttttctac ttatcagtag gtattatgtt tagacttaca 4040461 tacgatctgt ttaattcagt agcattagca atttttattg tgtatataat tttagatagc 4040521 ttgtatttcg gcgttaaatt attacttcct aatggatatt gggaaccctt tagagacttg 4040581 gctatattca caaatatgct caatagatat tggtcaactt caaatcttat aatagtttat 4040641 attagacaga taataatagt ttttattttt tatttagttg gatcttcaat ttttttgaat 4040701 aaggattata aaaaatgagg attaaaggct ttttcataac tttagttgcg ataatatttc 4040761 aggcgtcatt atcgagttat aataataata aaaatgtctt tcctttttta gatggcatac 4040821 caataagcac ctcgggtcat tatgagtatc aaaatatttt attgtggttt gtacctattg 4040881 tttccctaag tttttgtttc tctgggagta ttagagatac atacatttcg tatgagcaat 4040941 taaagttagt aagagaacat agtagagtta aatgggtaac atctcaattc ttaataatta 4041001 cagttgtact tttaatcttt actttatctc agattgctat attttatatt tattcacttg 4041061 tatctcttca taaccttgat attaattccg ttatcaataa aagatttgtt atgatgacac 4041121 tcatgtatta tctaacctta cttaacttat ttagttttca attatttatg gagctttatt 4041181 ataaatctca aatagcacaa ttaaatataa gcgtttatat tattttttcg ttaattttag 4041241 caaagaagtt agtgcaatta aattctccga aagttattca ctacttttta attccaaact 4041301 acagtaatgg attaagaact gggttaagct attattccca atctggaact gctattattg 4041361 aaccattatt aggtttgttt attataatca ttttacagat ttcaatagtt atattatctg 4041421 tcttaaagtt caaaaaaata gatatgctaa aaagtgaggg cttacaatga ttgaggtatt 4041481 aaacctaaca aaaaaaatta aaaagactac agttttagat aatatctctt atacatttga 4041541 aaaaggaaca atttatggac tatttgggag taatggttct ggaaagacca tgctacttcg 4041601 tgcattatcc gggttaatag tccctactga agggagtata actattaaag gtgaacaatt 4041661 acataaagat atctcttttc ctaaaagtgt aggattaatt atagaaaata tgcagttact 4041721 tcctcagtat gatgctttta ctaaccttaa aattttgtca aaaattaaaa agatcgcatc 4041781 agataatgat atattagatt ctattagtag agttggtttg gaaaatttta atagtgtaaa 4041841 ggttagtaaa ttctcgttag gaatgaaaca acgattaaat attgcacagg ctatttttga 4041901 aaaacctgat atattgctac ttgatgaacc aacaaatgcg attgatgaaa aaggagttgc 4041961 atttgttcat gacattcttt tacaagagaa aaaaagggga gctaccatta ttattactag 4042021 tcatcacaag gaagatatta tatctttatg tgacattgca ttagaaatga atcatggacg 4042081 tctagaaact tcagaaaaag taatatataa gaaagatagt tagtttaaac tggctatttc 4042141 ttatccaatg atagactgca gacaagttca actgctgtaa tgctagaaaa tccaatgaaa 4042201 tgctgataat tgcgaagaga tatgatcagt cagaaaacaa atcttaaaaa gaaaaagtaa 4042261 attcatcaat atttctaata aacctggcaa acaacctgtt cggaggcatt atagctactt 4042321 cactgacggg atatttattt gatgtgacag gctccttacg ctcagctttc tggtgccggt 4042381 tttgtgttgt tgctgggatt ggttttttat gtgtttgtat taggggatgt aaaacgaatt 4042441 aaactggaat aaagagtgct tgctgaaaag cactcttttt ctgcatcgaa agaatactta 4042501 agataagtca ctcccaaaaa tcgtaacagt ctgacggtta aacataaacc tctgcccgtt 4042561 ccattttaat acggtttgaa catatcccaa tgagtcggcg ttataccttc ccgctatccg 4042621 ctggtacgcc aataattcgt atacgccgtc tctgtcaaaa tcaaccggat acaagcccga 4042681 taaaggattc acccatcctt ctatcggcat ttttaacaca ccttggctgt tataaatctc 4042741 attcaaatat tccctgccct tgtaagtaag gtcgaggata tacgtttcgt tttgctgatg 4042801 actgataacg ctcgctttat attgattttg atacctcaca ctgtacttta attcatcatt 4042861 caatacatct gaattgaaaa ttcgccggaa ctgcctgttt agataggcaa acacatatgc 4042921 ataaatagca ccgccgcttc cccctgtgtc cattactact gccacatcct caatcttgtc 4042981 gcctgtcata tcccccagaa aaagtgacgg attgtatccc atattgtttt gaagctgaat 4043041 ccgctgctcc tgatgggttc tgccatcacg gatcaccaat gtgatatttc tccataacgg 4043101 gctgccgggc atttgatttc cagttagaaa gacctcgtca ataacgccgt ctcccgttac 4043161 atcgccgcgg gtagatacaa tgattgcacg tgaggagaca ggctgccgaa atacgtatgg 4043221 atgttgaaca agtcctctgc cttcataaaa ccaataagga gccattctga tgtcatacac 4043281 attcaattgt gtcaccttcc ctaatcagct gaatgaatca ttatatgcag gaatggcaca 4043341 tcaaagacat atcttacaca ccaattaaat ccgtaccata tgaattatca attacacaaa 4043401 gccactcgcc ttgcgcattc tttttaaata cataggtcgc ccttctttcc atcgcatact 4043461 cggagtcctt tttatccgaa tcaagcagtg tctgagaaag aacgagtacc gtgtcacctg 4043521 cttccaacag gatcattttc ccttgtgtcg ggacaatatg atgattgaaa tagttcgcaa 4043581 tcgtgataaa cgcttttttg atttcttcct tgcctcgcgc gatcatgccc ggcttcacaa 4043641 ctaaaacggc atcttccgaa taataattca tcagtgtatc aaaatcttca ttttggattg 4043701 ccaaatcaca cgcagagatg atgtctttca attgctgttc caaatgaatt cccccaatca 4043761 tcatgattgg atatattata catcgctaga ccactgaaac cttgaaaaca aaatgaaaag 4043821 tatccttttt tcctatataa tcaaatagat atatttaaca aagtacccaa gtgaaggggt 4043881 gaacattatt gtctgcggaa gtaacgttac atgacaatat acattatgat ttaagtgcgg 4043941 attgccagca ctgttttggc ctgtgctgtg tcgccttgcc ttatgcgaag tcggcagatt 4044001 ttgcttttga taaagacggg ggcacgcctt gccgcaactt acaatcaaac tatcaatgtt 4044061 ctatacataa agatctcaga gaaaaaggat ttcgaggctg ctctgcatat gaatgctttg 4044121 gcgccggcca aaaagtatcc caaatcactt atgagggaaa ggattggcga aacagccccg 4044181 aaacggccaa ccagatgttt gacgtttttc ctatcatgca gcagctgcac gaaatgctct 4044241 ggtatttaca tgaagctctt tctatagata tagccaagcc gattcattct gaactgagaa 4044301 ccactttcga aaaaatagaa aggctcacca gactcagcaa agaacgcttg ctgacactgc 4044361 aggtggacga gcatcgagct gaggtcaatg aatggctgtt aaaaacaagt gaactggtgc 4044421 gtgcccaagc ccgccatcca aaactcccga aaaaggtcag ccggggaagt gtcctgatcg 4044481 gcgcgaaact gaaagggctt gatctgcgag gagcaaatct aagaggggcg ctgctcatag 4044541 ccgccgatct gagaaatgcc gatttgagaa tgacagactt tatcggtgca gatatgagag 4044601 acgctgatct cagcggcgcc gacctgaccg ggagcatctt tttgacacag gcacaggtga 4044661 acgccgccaa cggcgattcg aatacaaagc tgccgctgtc tgtacgaacc cctgcccatt 4044721 ggaaataaaa aaggacccgc taacggtcct tttttactga tcaattcaat cctttttcgt 4044781 tcctcttatc cggcattttc acacttcttg ccaagtatcc cgacagccat aacgcaacca 4044841 gcagcatgaa ggtgatcata ccgacgacgc ccagccagtg aaaaccagac cagaatagcc 4044901 ctccgattgt tccgaaaaca cttgaaccgg cgtaataaaa gaacaaatac agcgatgaag 4044961 cctgtgcttt gttgtgaagg gctctcctgc ccacccagct gctggcaact gaatgccctc 4045021 cgaaaaaacc gaatgtaaag agggcaatcc ccagaatttt cactgccagc atattgttta 4045081 tcgtaaataa cgcacctgca atgacgatga aaatattcat caccaatatt ttcggatagc 4045141 cataccgatc aaccattctt ccaatgaaag acgagctgaa aatgcctaca atcatcacaa 4045201 taaagatcca gctggaaaat gctttattaa gcgaatacgg cgggcccaac agcacataca 4045261 caatgtaatt aaacaaggca acattgcttc caagcagcaa aaaaccaatg agaaacaagc 4045321 tgaatagttt acggtccctc aagtggccga tcagagacat tcccaatttc ccgagcttca 4045381 attttcttgg cgtaaaatgc ctggatggcg gcaaatttat aaaaaatata acactagcaa 4045441 tcaaactaat gacaccaatt gtccccatcg ccatatgcca attcaagtac tcgctcagga 4045501 gcccggaaac gatccttccg aaaacggcgc cgattgcatt tccgctgata tatagcccca 4045561 tcgctgatcc aagacttccg ggttcaattt cttccccaag ataagccatc gcaatcgacg 4045621 gaaggcctgc gagcgcaacg ccttgaatgg ttctcaatac gagcagtgta tgaaagctcg 4045681 gactaaaggc cgatgccaga cagagaaccg atgcggccag catggaaata cccataatag 4045741 gcttgcgtcc ccacacctcg gataatgaac caaagacaag catgctcaca gctaacagca 4045801 ttgtggtaac agataaagaa agactcgccg cagtaggcgt tacatgaaat tcccgcgtga 4045861 attcctccat gagcggctgt acgcaatata gaatcgcaaa tgtattgaaa cccgcagcga 4045921 agaaagcaaa cgtaattttt cgaaaaaccg gtgtgccttt tcgaatgtat gtcatcggga 4045981 ctttatcggt ccctcatcat gttgtggagc actgccattc ataaacaatc atcctttatt 4046041 tcttacgaat tcaaacatcc tcgagtctgt ttatattatt atcttagcac cgttgatata 4046101 tgttgtataa tgcatataaa atatcctttt catgcttata tgtaataagg agagatgata 4046161 attggaatgg gaacaacttg aatattttca aacactggcc cggatgcagc acgtcacgaa 4046221 agccgcaaaa agcctctcca tcacacagcc tgcactttca cgctctatcg ccaggctgga 4046281 aaatcatttg ggcgtcccgc tatttgacag gcaaggacga tccatcagct taaatcaata 4046341 cggacacatt tttttacgac gggttcaggc gatgatgaag gagtataccg aaggaaaaga 4046401 agaaatccaa gccttattaa agccagacca aggcgtagtc tctctcggtt ttttacatac 4046461 attaggcacc acgctcgtgc ccgatctcat cggctccttt cagcaggaat accccaacat 4046521 ttccttccag ctgaagcaaa accactctta ttggctgctt gaacgattaa aatccggaga 4046581 tctggacctc tgtctcctcg cttcgattaa gcctgaaaat ccgatccaat ggatcaagct 4046641 gtggagtgaa gaactctttg tatttgtgcc aaatgatcac ccattagcca gtcgcgaaag 4046701 cattaccctg aatgagattg ccggggagcg ttttatttta ttgaaaaagg gctatgcgct 4046761 tcggatgacg gtcgatgagc tgtttgagaa ggccaatata cagccgaaca ttatgtttga 4046821 aggagaagaa gcaactactg ccgcaggttt tgtggcagcc ggtctgggca tatctattct 4046881 cccagacctg aaaggcttag accaaagcaa aatcaccaaa atccgcgtca gctggccgga 4046941 atgtcagcgt gtcataggaa ttgcctggat aaaaggcagg tttttatcac cggttgctga 4047001 gacctttaaa caatatgtga tcagccattt ttctgagtag gaaggattca agcatgaatg 4047061 tcaaaaaaat cacgtcagaa caggatttac atacagcgtt tgaaatcaga aaggcagtat 4047121 ttgtagagga acaaggctgt cccatttcgg atgaattcga tgagttcgat acactccacg 4047181 gtgactgcca gcacatcctg gcttatcatc agaatgtacc tgttggcact gcacgtgtcc 4047241 gtatcgttgg ccacacgggg aaactggaac gaatctgcat tctgaagtct taccgcaaat 4047301 tcggtttggg aaaagtgatc gtcgatgcat tagaacgtat tgtaaaagaa caaggcattt 4047361 ctgccttcaa actgcacggc cagacacagg cggcaggctt ttatgaaaag ctcggctatc 4047421 ggactgcatc agaagaattt atgctggacg gcattccgca tgtgctgatg acaaaacaag 4047481 acgattctgc gctatagatt gttcacaaat ttgtcactta tgagcatgaa cggttcattg 4047541 gtatactaat caccgattat ggagagaagg aatgattgta tgccagcaaa taaaaaagaa 4047601 ggccttatat ttggcgtgat gatgtgcttt ggaatggttt gcgtcatgtc gatttacaat 4047661 gccatcatca accgagccat ctacgatttt tcactgatga ccgtttttga aatggtcatc 4047721 ggttttatga tcgccctcct gttagattta ctgttagtgg gccccctcgc caagaagatt 4047781 gcattccgca tgccgttcga caagactaaa aaaatttatg tcatccttgc catgtcaact 4047841 tgtatggtga ttggcatggt actttgtatg tctgtgttcg gtttagtgac agcggttcta 4047901 gcaaatgggc tgaacgggga cagcctcttc agtgcttatc ttatgattgt gttgaaaaat 4047961 ttcatcctgg cctatccgtt gcaattactg attatgggcc cattagtcag aggagttttc 4048021 atgaaatttg taaaaccaaa gctcacagcc gcaatttaaa tagaaaagga gtgagcctga 4048081 cactcactcc ttttgctcat gaatcgaatg taaaacaagc tccgcaaaag cctctgcggc 4048141 aggcagctgc cattttttct ttttgggtgt gagtaaatcg gatcgagggc ttcaccatgc 4048201 tggagatttt tcagcttatg tttttcactt ccattaatcc ctatacctta ccacatagtt 4048261 tttatacaat tcttcgttat aaaggatttc ttcgccatgt gaagagcaaa tgagcgttgg 4048321 tttgatttga tctatgattg agccgctgtc gatgttctca tttatatcaa cactgaatct 4048381 tcttataggt gggtgtaaat cctccttact tgtgataaaa aggtcgcccg tcaatagcgt 4048441 acgatcgatt ttatgataat acacaacatg ccccggcgaa tggccaggtg ttaaatagta 4048501 tttcagaggc agatgagcaa gcgtttgctc cgtcagcggc tgtacaatat gggctacccc 4048561 tgtgttctcc acttcatttt tgttcggata tggctcttcc ccattgatgt actttagttc 4048621 tttctggtgc gcaaaaatcg gaatatcaaa tctctctaac cattttgatg cacccccgat 4048681 atgatcactg tggccatggg taagcaaaat ggcttttgga ttgccgatcg ctaacgctgc 4048741 cctaatttga gcatcagcaa aacgttctat tcccgtatca acaatataaa catcatcacc 4048801 atctttgata aaccaggtat gaaccggaat acgaagaggc acatcaagct caaattcaca 4048861 ttgaaagaca tgttctgata gttgtctcaa attcacgcaa accatctcct gtggaaattt 4048921 tttgatagtt ttaaagaaaa cagaagtgaa cggactattt tcacccacgc tcgagctgac 4048981 tggattcttg agaggaaacg ccgattttcg ccagcatcag ctcaacttgt taacgttgtc 4049041 cattaataat cccttttgtt ccccttcttc acatattccc aatcacgttc tatattcttc 4049101 ctcactctat gaaggagtgc agaaatggtt tccttttcct ctgaagtaaa accggacaag 4049161 gccacttccg tggaatgttc tccttctctt cttaacaatg gatatacctt tttccctttc 4049221 tcagtcggga acagtttttt tattttttta ttttgctcat ccggcagttt ttgaataaat 4049281 ccctgcattt ccagcttctt aatggcccgc gcggccgttg tccggtccac ttttatcatt 4049341 tccgccaatt tttcttgaat aattcccgga ttttcgtata tacgcacgag atagagatac 4049401 tgccctcttg ttaagtctaa atctttaaat tcgatgttgc ttatggaatc caacgctctt 4049461 gctatcatgc cgatctcacg caaaatatca ttcattccta aaacccctca cgtatttttg 4049521 ttgcaattac aacaaaaatg ttttaacctt actattataa gaccacatgc gtgctgtaca 4049581 gtccagacta atatcagaaa aggattgatt cataatgaat ataaaaagaa taacaactga 4049641 agctgattta catgaagctt taaagattag aagaggcgtt ttcattgagg agcaacatgt 4049701 gtctgaagcc gatgagttcg atgaatttga tacgcttcag gaacaatgcc agcatatctt 4049761 ggtatatcat gagaatcagc ctgtcggcac cggacgcgcg cgcatcgttg gccatacagc 4049821 aaagctggaa agaatctgca tcctaaaacc ttaccgtaag tacggattgg ggaagatcat 4049881 cgtaagcggg ttagaggaaa tcatgaaaga aaaaggactg acttcatata agctgcatgg 4049941 tcaaacacaa gcggcaggct tttatcaaaa actgggctac cagatttctt cacaggaatt 4050001 tatggaggac ggcatccctc acgtcttgat gacaaaagaa atatcgcgga atataacatg 4050061 aaatatatgt attacggaat aggcatactc atattaagtt tgggcatttc cttaaccata 4050121 caatcaggac tgggcacatc acccttcgat gcccttttgg ttggtctgtc aaaaaaaatc 4050181 ggtcttaccg taggaagctg ggaggtcctt atttctgtga tcctcttaat ctgcaacgct 4050241 atattaacga gaaaaaaacc tattttgctg ggcttgatta cagcattcat tactggaata 4050301 ggcattgacc tatggttgtt tgttgtaaaa aacaccatct atctaaactc gttgttaagc 4050361 aaactgattt gttttggaat tggtttggtg ctcatcggtc ttggaacagc catctatctt 4050421 cagacgaaat tcgcatcaac accgatcgat catttaacac ttattatccg agatctctcc 4050481 aaaagaacaa tattgttttc aaggacattg gtatacgctc ttttcttagt attagccatc 4050541 atctttaaag gccctatcgg catcggaact cttttaacgg tttgtttggg aggaatgctc 4050601 cttcacgttt ttatgcctat tgtggaaaga catttcttat caaagaatag aagaggttat 4050661 taagaaacct cttctcgatc caaaaaacga aacgcaaaac aagccccgtt tcgttgtcaa 4050721 ttctttatct ctggtactgt tgaggtttta taatcaatta aaatttatag taccaaaaaa 4050781 tcgcaatttc atttgctgtt ggaaagttgg aataaagcat cgtatcaacc gcacctatta 4050841 taaagtgatg tttggcataa aaatgacaag ctgaaatatt aatatcttgg gtttcaagca 4050901 taagaccaca aaaatgattc tcctttgccc actcaatcgc tttatgtaat aatgctgttc 4050961 caacaccttt ttttctatag tcttttgcca cggcaatgtc ctctattagt gcatacccat 4051021 tccagttaga acggatctta atccggccaa tgcagttgtt ttcaagataa tataaaaaag 4051081 ccgctttccc ctcttcttca acataactaa catccatgtc atcatcttca tattgtttaa 4051141 aataaggttt agaaaatcgt tcctcagtat atgtccaaac accgttttca aaagcaggta 4051201 tcattctccc aaaaacaacg aaaggttcgt ttggtttatt gaaatctttc atattcaaat 4051261 gagtcatttt catgatcata tcaatctccg ccaatcgaga taatatttag taaactcgtt 4051321 tcgatactat tcaacaacag cttccaaaag tgtactcttt aagagaacag cattagataa 4051381 ggcatccatt accttatata tttcactatc ttaatgaggt atttcaacag aggcttgtgg 4051441 tacagtaaaa aggaatagaa acaagagaaa agaagatgaa cctatgccca ctaacaataa 4051501 actcaatgag aaatatcata cttccttcaa ctcgcccaca accctgttga ctagtatccg 4051561 tggagagagg aagctttgac acagcttctg ccattgatga catctctatt gaagtatcca 4051621 aaggacaacc aaggatcgct ctttgacttt ttcaagaaga aagtagagtg aataaaggag 4051681 tgattgagta tgttaacaag agaagatatc tttaaacacg tcaaagaaaa atacggtaca 4051741 tcgcctgatt acccgtggga gaaataccca aactatgctt ctttgagaca tacatcaaac 4051801 aaaaaatggt acggtcttat catgaatgtt ctcccagaaa aattaggctt ggatggtcat 4051861 ggcgaaatag atattctaaa tctaaaatgt ccccctgaaa taagtgatcg cttaagaaac 4051921 ggggaaaata tcttacccgg atatcatatg gataaggaac attggatttc aattgtttta 4051981 gaacggacag atccagaagg cgaaatctat aacttaatcg agcagagctt tcatttaacc 4052041 aagtgaagat aaagagtgtt cctgctaatc aagctgcgaa gagtagtggg cactttcatt 4052101 ttaggatact gttcttcact ctgtccacaa acgcaactta gttcatctgg tgcgagagtg 4052161 ggagaagaat ttcaaccaac ttcttatgta aaaggatgaa tagttatgac aaataactta 4052221 aaacagagaa gaatcatttt agatttagca gttactttag atggttttat tgaagggaaa 4052281 aatggagaag ttgattggtg tattatggac cctgatatgg ggtttactga ttttttaaat 4052341 caaattgata ctattttata tggtagaaaa agcttcgatt tatggggaca atacattcca 4052401 aaaaatgaag accctgatac agaaaaggaa ctttggaaat tggttcatag taaaaagaaa 4052461 tatgtttttt ccagaacaca aaatgagatt gataatcaag ccatatttat aaatgataat 4052521 attcttgaag aagtaaataa attgaagaaa aatcctggta aagacatctg gctatatggt 4052581 ggagcgagtc tcattacaac ttttataaat ttggggcttg ttgatgaatt tagattatct 4052641 attcaccctg ttgttttggg agaaggaaaa ccgttgttta ttgatgtaaa acagaggata 4052701 aatttaaaaa tggtgaatac aagaacattt tcctctggcg ttgtgcaaat cgtttatcat 4052761 tggaatggct aacattgtaa agtaacactc gacagtaatc cttcttattg aactaaaggg 4052821 gaatccataa ataatgggtt ccccttaata tactatggaa ttatcaatat caaattttct 4052881 gtaataaaag aggattgaaa aggacgatgt ctcctcaatt aacatcatta agcattatag 4052941 tatattttct tctccctctt ttaagtaatc ggctaagttt tgtatttata aaaaaacgaa 4053001 agaaggtgat ccaatgccta ctaacaataa acccaataga ttaatcgctg agaaatctac 4053061 ttattttact tcaacatgct cataaccctg tggactggtt cccttgggga gaagaagcat 4053121 atgaaaaagc gaaacgcgaa aacaagcctg ttctcgtatc tattgggtat agctaacgat 4053181 ggctaatcta aagaacatgc tattgatgcc atgtttattc attttacaaa aaaggatcaa 4053241 ccttgaatta ctttcacaag attgatcctt tcactcattt agccatgtct ccgcgaacgt 4053301 ttatatacat tcaagattac tagccaacaa ataacaatga ttcctgcaaa aagtatgagc 4053361 atattgctat acaaataggt agagtgatca acgtcaatag gcagcagcct atgatctagg 4053421 aagccgatag ataataaacc gcctacaatc gcaatacccg ttccctctga taaaaagctc 4053481 gtgaaattaa gcaaactcat tccagcgccc gcttcctttt ctttcaaact gctagacaca 4053541 actgtagata taactgtttt tgtgaaagat agccccccaa aaacaaaaat tactataatt 4053601 gtcatgatcc atggtgctgc atctataaaa aaggcagcga ttaaaaagcc ggaagaaagc 4053661 aatgcacttc caatagttag tacatacaag gaacctttcc gatcaacaag caatccccca 4053721 atgtaaccaa agatgatgac actcattgtt ccggggaaaa taatgccgct tccaattgct 4053781 gcagtactta aatggtgaac atctttcatc atgtaaggaa ccatagagac aaatcctgct 4053841 actgtaccaa atattagtcc tccgcaaagg gttccaatca caaaaaagac gtttttccct 4053901 aattcagggt caacaaaagg gtcctgagct ttcctaatgt gttgcacaaa tatgaagaaa 4053961 gcaaggatac tgatgatcag aaaagaaaat ctataagatg ttgtaaacag cataaaaaat 4054021 acgatacctg cagacatcaa tataatccct gccatatcaa tgtgtcctct tattctctct 4054081 tcctttttca acaattttat aaggaatgga acggtgataa ttgttgcagt tggaataagc 4054141 agcaaatacg accaatggat ataatgagca accattccgc caatagctgg cccaacacct 4054201 tctcccattg ctaccaggga cccgatcagg ccaaatgctt tccccctgtt ctcttttgga 4054261 atatagcgcg caacgacaac catcacaaga gctgggaatg cggctgcacc aattccttga 4054321 ataaatcggg ctagaatgag aataggaaag aaagagtgtc caacaaatcc aatgatcgac 4054381 cctaagccat ttaccataat cccaaataga agcagatttt tgatgcccag ctggtctgat 4054441 agctttccat atagagctgt tccaatggag aaggttaaca taaaggctgt attcacccag 4054501 tttgcacttg ctggcagttt attaaactcg ttggcaatat caggtaatga gacgttcaga 4054561 accatttcat ttaatacgct gaaaaatgat agaacacaaa gccaaatcaa aacttgattg 4054621 tgccgtaaag ttgactgtga ataagacgta ttcacaattt cccctccatt aatgagggca 4054681 gacgcagttt atagggtcat tgatacgctt ccctctttta attgtaccct gttcatttta 4054741 ttgcacttca taataactcc ccctacattt gattgatatg atcttattat atatagacta 4054801 aggattaaac ttttactttt tttataaaaa tttgaccaga ttgcgaaaca aggaaaaacg 4054861 ttattcgcat ttatctcaag tggcaaaatg aaacattagt ttatattttc acatcacaat 4054921 tatcgataag cagtcagtta ttgtatttgt ttaggataac tgtggtaacc tgaatataac 4054981 caacttagga agaaggtgat cccatgccaa ataaaagtaa acccaataga ttaatcgctg 4055041 aaaagtctcc ttatttactc caacacgccc acaaccctgt ggactggttc ccgtggggag 4055101 aagaagcatt tgcaaaagca aaacgcgaaa acaagccggt tctggtcagc atcggttatt 4055161 cgacgacttg tcattggtgg cctgggataa tcaaatcgtg tggaactcca ttaaaagata 4055221 acagaagcca ttttaaacga taatactatt tgttcaaaca atacagtcta ccttttattt 4055281 cattcatttt ctaaaacctg taatccgtaa ccacgcggta gcaggttttt ttatttgctt 4055341 gacttagagt taactctaaa ttgtaaacta actttaatta aatgagaggg atgatgttgt 4055401 tgtattccat tagtaaagct gctgagaaga ctagtattag ttcgtataca ttaagatatt 4055461 acgaaaagat tgggttactt ccaccaccaa aacgaaaaaa cagtggaagg cgtttttata 4055521 cggagactga tattcagttc atgttattcc tgaaaagttt aaaggaaaca ggtatgtctt 4055581 tggaggatat taatgagttt gtcaaagacg gatgcatttt ggaaaaaatc aattcggatg 4055641 ttaaatcggc acaactctcc ccatctataa ataaacgtat tgagatttta accaagcact 4055701 tagagaaaat ggaaattaaa aaaagggagc tggaagaagt gatttctact acaaaaggaa 4055761 aactggatac atattattca attttgaaag aggaagtgga aaacaaatga aacatttaaa 4055821 tatatacata atgttacttg gcttctctat tttcacggga gctactttta atcttgcaaa 4055881 atatacagtt ggatattttt ctccatcgtc ttctgcggca tggcgtttcg gtttagcggc 4055941 tgcagtgatg ctcatcattt tgatttttac tgaaggtata aagaagagtc aattacggaa 4056001 aaacgccgtt tcatacattg ttcttggaat tataggaatc tttggattta atgccttgtt 4056061 ttttgttggt ttaaaatata catctcccgt taacggagca ttaataatgg ggctgaatcc 4056121 tttattaaca gcaattctcg ctcgaattat cttaaaggac aacatgacaa aaaaacaagt 4056181 actcggcata ttctttgcat tcatcggtgt attgttagtc attacacaag gttctatcga 4056241 aaccattaaa accttatcaa tttcaggagg agacttaata atctttacag gtaacgtttg 4056301 ttgggcactt tatggcgtac ttggacgtcg gtttgtaaag gatggtacac cgctatctac 4056361 aaccacttat acgatggtta ttggtgctgt tagtttaata gtagtttcct tatttacatc 4056421 caaacctgtt tctttatcga acatcccgat tggagtttgg ggggcaattg cttttatggc 4056481 tttttttaca agtgttttgg gttacctatg gtggaatcag gggattaaag agattggagc 4056541 tagtaaaaca tctttatttt tcaaccttgt tcccgttgta acgatgatta tttcatttgc 4056601 cgttggaaca ccaataaagg tatttcaagt tattggggct gtgctagtta tattaggcgt 4056661 tttaaccgct tcgggggtaa tacgtattcc taagtacaat actaaagaac agtcagctat 4056721 ataaagaaat agggagtatt tttgagaaaa tgtgttaagt taaatataca ctaattatag 4056781 gaagaaggtg atcccatgcc aaacaaaagt aaacccaata gattaatcaa tgagaaatca 4056841 ccatatttac tccaacacgc ccacaaccct gtggactggt tcccgtgggg agaagaagct 4056901 tttgaaaaag caaaacgcga aaacaagccg gttctggtca gcatcggtta ttcgacttgt 4056961 cattggtgcc acgtgatggc ccacgaaagc tttgaagacg aagaaatcgc gcgtcttctc 4057021 aatgaacggt ttgtggcgat taaagtcgac cgggaagagc ggcctgatgt ggattctgtt 4057081 tatatgagaa tctgccagct gatgaccggg cagggcggct ggccgctgaa tgtgtttatc 4057141 acgcctgatc aaaagccgtt ttacgcgggt acatattttc caaagacgag caaattcaat 4057201 cgtcccggtt ttgttgatgt gcttgagcat ctgtctgaga cgtttgcgaa cgaccgcgag 4057261 catgtcgagg atattgcgga gaacgccgct aaacatttgc agaccaaaac agctgcaaaa 4057321 actggtgagg gccttagcga atcagcgatt caccggacat tccagcagct tgccagcggg 4057381 tttgacacga tctacggcgg tttcgggcag gcaccgaaat ttccaatgcc tcatatgctg 4057441 atgtatttgc tacgttatga tcacaataca gggcaggaga acgctctata caacgtgacg 4057501 aaaacattgg acagcatggc gaatggcggc atttacgatc atatcggcta tgggttcgcc 4057561 cgctattcga ccgatgacga gtggctcgtt ccccactttg aaaaaatgct gtacgacaat 4057621 gcgctgctgc tgaccgctta tacagaagcc tatcaggtca cgcaaaacag ccgctataaa 4057681 gagatttgtg agcagatcat tacgttcatt cagagggaaa tgactcatga agacggaagc 4057741 tttttctcgg ctttggacgc ggacacagaa ggagaagaag gaaagtacta cgtgtggtca 4057801 aaggaagaga ttctaaaaac gctcggggac gatctcggaa cgctgtattg ccaagtgtat 4057861 gacatcactg aagaaggaaa ctttgaaggc aaaaatattc ctaacctcat tcacacaaag 4057921 cgagaacaaa tcaaagagga tgccgggtta accgaaaaag agctcagtct caaactcgaa 4057981 gacgcaagac agcagctctt gaagacacgc gaggaaagaa cctatccgca tgtcgatgat 4058041 aaagtgctta cctcatggaa cgcgctgatg atcgcgggtc ttgcgaaagc ggcaaaggta 4058101 taccaggagc cgaaatatct cagcctagcg aaagacgcca tcacatttat tgaaaacaaa 4058161 ttaatcatcg acggccgtgt gatggtccga tatcgtgatg gcgaagtgaa aaacaaaggc 4058221 tttatcgacg attacgcttt tctcctatgg gcttatctgg atctctatga agcttcgttt 4058281 gatctttctt atttacaaaa agcgaagaaa ctgacagacg atatgatcag cttattttgg 4058341 gatgaggagc atggcggatt ctacttcacc ggacacgatg cagaagcctt aatcgtacgg 4058401 gaaaaagaag tgtacgacgg cgccgtgcct tcaggaaaca gtgtggcagc tgttcagctg 4058461 ctgcgtctcg ggcaagtcac aggcgactta tcactgatcg aaaaagcgga aacaatgttt 4058521 tccgtgttca agccagacat agaagcgtat ccgagcggcc atgctttctt tatgcaaagt 4058581 gtgttaaggc atctgatgcc taaaaaagaa atcgtgattt ttggcagcgc agacgatcca 4058641 gccagaaaac aaattatagc ggagcttcaa aaagccttta agcccaacga ctccattctg 4058701 gtggcagagc agcccgagca atgcaaagac attgcgccat ttgcagcaga ctaccgcatc 4058761 atagacggca aaacaaccgt ttatatttgt gaaaacttcg cctgccagca accgacaaca 4058821 aatattgaag aagcgatcca cacattaata agcagcaggg attaagaccc ttgctgctta 4058881 ctttttgatt tcttatggta ccataaagcg atccccgcaa acacaaggtt gaccgctatc 4058941 gtaaagaaag cctcccacat cgggttcccc cgcgtaacgg taaacagaga aggaattcct 4059001 ccatacacac tgtttttttc tgtaataaac atacacaaaa acatattatt cgcggcatgg 4059061 gcgccaagtg atatttcgat gctcccagtt ttaatcgtgt aatacgtcca cacaaaccca 4059121 aatgttaagt actcaattcc tgcccagaca gcgccattgt tcatttctgg attcgcaaaa 4059181 tgcaatacgc caaacaatcc tccgacaatc agtgtcaaaa atagaggatt tttcgtcaat 4059241 ctcccgaaag cttgaagcaa aaatcccctg aaaaatagtt cctcagctga tgtctgaatc 4059301 ggaaccaaaa tgagggcagc cgctagcagc cagataaatc gtgatgcatt aaactcttgc 4059361 attgaatagc tatcaggatg aatcacaaaa tcaatcaatt gtacggcgat cattagcaag 4059421 aaataagcaa taaaaccaaa ggaaattctc cgccaattca tctttgaatt tggtgttatc 4059481 accgttcgga aaggccgctt caaaataaag cgcacagcca gccaaactcc cggaatggcg 4059541 aataaataaa tcacatggga caaataaaga tctacgaggg gatcactcag cacagcttca 4059601 tccaaatcaa acgtgatatt gggattcaca ataaccgtga acaatatagc gaaaaggtaa 4059661 gctatattcc ctaatacata taaccctacc atcaccaaaa aagcgaaaaa atatctccac 4059721 aacgtattgt ttccttctat aggacggata aatgaattca ttccttctat gtctcttcct 4059781 ttcaatgaga atattactat atatttgcat aaattggtct atgaatctac tgttttggaa 4059841 atcttttaag caaaattaaa atataaagtg tgaatttagt tcttccatct agtgatttga 4059901 actctgttgc caatgaacca agatacttat aatagtccca agaggggaat tttcagtctt 4059961 ttctactact caaaaggggg ttttttatga atacgatctt caaacaaaag aatacacatc 4060021 ctttctcaaa cgcagcgaat cgtttagacc gccttccgat ttcacgcgtt catttccaag 4060081 tgttaaccgc tctcggcatt gtttatttct ttgatctcgc agatttattt accctcagca 4060141 acgtagcgcc ggcactgatc gagcattggg gcatcccgct ttcaactatt gctaacgtaa 4060201 cggccgcttc gtttttaggc atgtttttag gcgcttcact gggcggacgg ctgtccgatc 4060261 gaatcggccg caaaaaagcc ttaaatctat ttgtctttgt tttctcaatc gcatcgctat 4060321 gcaatgctgc ggcatgggac attccatctt taatgacatt ccgtttcctc accggatttg 4060381 gcgttgcagc cgccatggtc attacgaata gctatttggc ggaatttttc ccttcaagtg 4060441 tacgtggaaa atatatttct ttttgtgcca tgattggatt gattggggtt ccgatcacca 4060501 acattgtgtc tgcctttgtc attcctcttg gttcatgggg atggaggcta gtatttgtat 4060561 ggggtgccgt cggccttatt tattttttct tcatccaccg tctggaagag tcacctcgct 4060621 ggcacgaaaa tcgcggggaa tatgcgaaag ccgatgcgat cctcacccga attgaagaac 4060681 aggttgaaaa ggagaaaggc ccgcttccgg cagcatccca gcctaaagta agcgaaactg 4060741 ttaagcagaa tgcaggttac gcaggcttat tgaaaggcag aaacctcaaa attaccatcg 4060801 tattatctgc tgtatggatt tttgaaacgt ttgggtttta cggatttgct tcatgggttc 4060861 caagcctgct aaaaagcaat ggcgtaacca tggaaaatac attatggtat aacgtattgc 4060921 attccgtcgg cgctccactt ggcgcactgc tcggctccat gatttccgaa agatttcaaa 4060981 gaaaatggat tttagctgcg agtgcgtttc tgacggccat cgccgggctc ttatatggta 4061041 tgacttttat tcccatcatg atcattgtat ttggttttat cgtgaatatc acagaacggg 4061101 tctttacctc gaacttatac gcctatacat ctgaacctta tccgactgaa taccgctcgt 4061161 ctggcagcgg tttagcctat ggtcttggcc gtttttcaaa catttttggc tcattgcttg 4061221 tcggatttat tgccgttcag ctcggctata tcagcgtctt cttatttatt gggggctgtt 4061281 ggctcgcatg ctccttgctg ttaatcttct tcggtcctaa tacgaatgca aaacagattt 4061341 aaaaaagtca gtgcggatct gccgcactga tctcattaca attgcttcaa aatccttgcg 4061401 gggtttccgc ctacaacagt attagcgggt acatccttag tgacaacaga tccagaagca 4061461 atcactgcgt tatcaccgat tgtcactccc gggttaatca ccgcccggcc tccaatccaa 4061521 acttgatctc caattgtcac aggcttaccg aactccttcc cggatttcct ttcgatcgga 4061581 tcaagaggat gaccggccgt gtagatatgt acacctggcg caatcaaaca atgacagccg 4061641 atacgcacct cacacacatc taaaatgaca cagtcaaaat taacaaatgt atgatctccg 4061701 atatgaatgt gatagccata atcacagcgg aatgtcggca aaatcgtgac ttgatcccca 4061761 accgaaccga gcagctcctt caaaagcttc gtccgcactg catcatcttc cggtgtttcg 4061821 ttgtattgtc taatcagctg tctcgcatgc ttgcgttcta gtaatagttg ttgatcttcc 4061881 gaattgtata attctccggc tgccattttt tctttttctg tcctcagcat ttaagtcact 4061941 ccagatgtca gattgtaatc tcgatcaaat ttccttcatc atcctcaatc acgctttcat 4062001 agtagccgtc tcctgttgtc ctcgggccgt ttactactgc gaaaccatcc gccttcaatc 4062061 gatcagtcag ttcgtcaact ttctcccggc tcccaacgga aaaggcaata tgtgcccagc 4062121 ctgtcattgt ttgtgagggc ggatcggtca cattcccttt tttcataatt tccagccttg 4062181 ctccggaatc aaacgtaata aaataagact taaaatcttt tttctcatta tgatacaaat 4062241 cattcgcttc gccattaaaa tacgattcat aaaaagactt cattcgctct aaatcattga 4062301 cccagaccgc tgtatgttca atctgcattt cttcctcctc cttcgccttc aatgaagtta 4062361 taaggtatga aatgcatttc agttcaagct tttttcttaa atttatgctg aattttgata 4062421 tcagcgggtt catcctgcaa aaatagagaa aatgctgcga tgccgagctg ctcaagattc 4062481 aaatcaagcg acggaaaacc aagaacacgg ctgatagaag tatttccctc gcctatgatt 4062541 tcaacatccc aattattctt tttggcaaat agatgaattc cagctgccac ttcatcacta 4062601 tttgcataaa tagcagtcgg aacccgcccg ctcatataaa aatgttcagc tgccagctca 4062661 ccatcattca tatcgttgca tccggacagc atatggcggt cttccaacct tccgcagaca 4062721 gctttatagg ccgcagcttt atcagccgtg ctcgggctcc tatcagcttc tctgacacac 4062781 gtaaaagcaa tattctcatg cccgcggctc tttaaatagc gaaagctctc tgcataagca 4062841 gtttttctgt cattaaaagc acaagggaca tcaatgtctc cggtatcctc acaagcgatg 4062901 accggcccat attcctgata agctaaaatg ctgtcccaat gattggcgcg ggaagtaatg 4062961 atgagaccgt ctattttctt cgttcttaac agctctaaat atttgatttc aatatcgggg 4063021 ttataattgg tggggagaag ggtcgttgca tactcatgct gaaaagccgc cttggtgatt 4063081 ccgttaacga ttttatcaaa gcagggatga tcgctataag gcagaatcac accgaccgta 4063141 tgggttttcc cgcgaatgag atcgattgcg gttcgatttg gtgtataatc caattccttc 4063201 atgacttgat gaacaagctt tctcttttct tcagatacat acggatgatg attcaataca 4063261 cgcgagacag tcgaaacaga tacatttgcc agtcttgcga tctcttttat atttgccatc 4063321 tctttctcct tttcatataa aaaaagcagt aagtgtaaaa tccttactgc tatctcatca 4063381 tatattgatg ataagttcaa caggacaatg gtcggaaccc atgacgtccg ctgatatgct 4063441 ggcatcttca atctgttcct taaggctttc agaaacaaca aaataatcaa tccgccatcc 4063501 aatatttctg tcccgggcgc cggcacgata cgaccaccag gaataagcgc cttcaagatc 4063561 aggataaaca tgacgaaaag aatcaacaaa gccagcttct aagaaacgag tgaatgcctc 4063621 tctttcttga tctgaaaatc cagcgttatt ccggttcgcc tttggatttt tcaagtcaat 4063681 ctcctgatgg gctacattca aatcaccgca taaaatcact ggttttttct gatccaattc 4063741 aagaatataa gacagtaaag cctcttccca ttgcatgcgg taatcaatcc gctctaatcc 4063801 ccttctggaa ttgggcgtgt aaacagtcat cacaaacacg ttttcaaatt ccagcgtaat 4063861 cactctgcct tcttggtcat gctcttctac tccgataccg tagatgacct gcagcggttc 4063921 ttgcttagaa aaaacagctg tgccggaata tccttttttc actgcataat tccagtacac 4063981 atgatagtct tcaggctgga gatcaacctg gccgtcctgt atcttcgttt cctgaagaca 4064041 tataatatct gcatcctctt ctttcaaata agagaggaaa tccatttttc tcatcacagc 4064101 ccgcaggccg tttacattcc atgaaatcaa cttcatgttt catcctcccc cctataaaaa 4064161 agagcaagaa cccgaaggtc cttgctcttt acatatcagc ttactcaccg cttacgtatg 4064221 gaagtaaagc catttgacgt gcgcgtttga tcgctgcagt caatttacgt tggtatttag 4064281 cgtttgttcc agttacacga cgtggtaaaa ttttaccgcg ctcagaaaca aactttttaa 4064341 gaagatctac atctttgtag tcgatgtgcg tgataccgtt agaagtgaaa taacacactt 4064401 tacggcgttt cgcacgaccg cctctgcgtc ctcctgccat tgtcatttcc ctcctttctt 4064461 tttcatttta ggcgataatc acattagaat ggaagatcat catccgagat gtcaatcggt 4064521 ttgccgtcgt tggcaaatgg gtcatcatta aagctgttcc cctgattgcg tctctggttg 4064581 ttttgatttc ccccaaatgg attatcattt tggcctccgc caaagtactg gcctccgccg 4064641 ctgtttcctt cgttgtatcc acctgaacca gaaccgccgc cgtttttcgg ctcaagaaat 4064701 tgaacacttt cagcttggac ctctgtcacg aagacacgct gtccttgctg gttttcatag 4064761 tttcttgttt gtaaacggcc atctacgcct gcaaggcttc cttttttcaa gaagtttgca 4064821 acgttttcgg cttgtcttct ccaagtgaca caattaatga aatcggcctc acgttctccg 4064881 gactggttcg taaatgtacg attcacagca agagtaaacg tagcaacagc cgcaccgttt 4064941 ggcgtataac gaagctctgg gtcttttgtc agtcttccga ctaatacaac tcggttaagc 4065001 ataagaaaga ccacctttta ccattatata tttcaaaatt gcttattctt cttctttaac 4065061 aacaatgtgg cgaatgatat cgtcactgat cttagctaga cggtcaaatt cttgaactgc 4065121 cgcagcgtca gattgaacgt ttacgatttg gtagaaaccg tcgcggaaat cgttgatttc 4065181 gtaagcaaga cgacgtttac cccaatcctt tgttccagtg atctccgcac cgttagaagt 4065241 cagaacgttg ttgaaacgct cgataactgc ttttttagac tcttcgtcaa tgtttgggcg 4065301 gataatgtac ataacttcgt actttctcat ctgtttgcac ctccttttgg actaagcggc 4065361 ccataatggg caaggagcaa taattctatt actcacaatt ttatattata ccaaagctct 4065421 tgtcccttta caactgcatc ctatacatta aatcggaaat gaataacatc tccgtcttgg 4065481 accacatatt ctttcccttc aaggcggact tttcctgcct ctttagctcc tgccataccg 4065541 ccgcccgcaa gaagatcctc ataagcaact gtctcagcac gaatgaagcc ccgctcaaag 4065601 tcactatgaa taattcctgc acactcaggg gctttcatgc cttttttgaa tgtccaagct 4065661 ctgacttcct gttctccggc tgtgaaatat gttgcgaggc cgagaagaga gtaagacgct 4065721 ttgatcagct gatcaagacc tgattcttga atgcccagct cttccaagaa catttgcttt 4065781 tcttcgcctt caagctcagc gatttcagat tcgatttttg cacacacaac gataacttct 4065841 gcgttttcgc cggcagcgta ctcgcgaatc ttcgctacat tttcattgcc agatggatca 4065901 gcaacttcat cttcacttac gttggccacg tacaaaatag gcttcgaagt cagtaaatgg 4065961 agctgcttca caagcttttg ctgctcttca gtgaattcta cagatcgagc aggcttttca 4066021 ctctcaaacg cttctttcag tttagataaa atctcaaact caaatacagc gtctttatct 4066081 ttttgcttcg caagcttgct gacgcgtgta atccgctttt caactgtttc catatcagcg 4066141 aggatcagct caaggttgat cgtttcaatg tcatcaatcg gatcaacctt tccggaaacg 4066201 tgtgtaatgt tgtcatcgga aaaagcacgg acaacgtggc aaatcgcgtc aacttggcga 4066261 atatgagata ggaacttgtt gccgagtcct tctcctttag atgcgccctt tacaatccct 4066321 gcaatatcag tgaattcaaa agcagtcggc acagtcttct tcgggttgac cagctcagtc 4066381 agcttttgca gacgatcatc cggcacctct acaattccca cgttcggatc aattgtacag 4066441 aacgggtagt tggctgattc ggcaccggcc tgtgtaattg cgttaaatag tgttgatttt 4066501 ccgacgttcg gcaaaccaac aattccagct gttaaagcca ttctttcatc tcctctatat 4066561 aaaaccgtca ttgtatgaac gtattttgaa cctagagcaa ttataaggag gttcactgga 4066621 aaagacaagc tgacaaaaaa gcattttcag cttgccaatc cctttgatta tgcttttttc 4066681 aagcctacta aacagtcaaa aagcgtactt cccattccat tatcagaatt tgtatcattt 4066741 gtcagtgcat tgactgaccc tccaaaagcc gcccacatgc cttcatctat attaatcgtc 4066801 ttcgcatgag cctgcttcat cactttcacc ttgcccttca tgcttccgcg gtcattaaag 4066861 atgacaactt cgtctccatc ctgaagatcc tgcccagccg ctatatctgg agaaatatcg 4066921 acctgaacgt gctgaagctt ttcaataaac ggcacatgct gtgaatgatt ggaacgctgc 4066981 ggatgaatgg ataagagcgt ataagggtac tttccagcta actcctcatt atggaaaaca 4067041 gattcttcgg gcacatttaa ttgaagcgag ccgctaaatc ctttttgctc agctagcgac 4067101 gaagtaaatt caaattttcc actcggcgtc aaaaactgat aatcatccca cggcacctgt 4067161 tttactggaa gagggaggtg gcctttttct tttaaacgct caagtgtcac atcctctgct 4067221 tccaatgaag aaagccccat ctctaaaaat tcttgagtgc tgtattcaaa cagctcgcca 4067281 aacccaagac gttttgcaag ctctgaccag atccagctgt ccgatttcgc ttcaccctgc 4067341 ggctccacaa gcttcttccc gtactgaaca taatgatgat acatactgga atagtagata 4067401 tcttcttctt caaaaacagt ggcagtcggc aaaacataat cacacagctc tgcggtatcc 4067461 gtcataatgg aatcaatcgc gaccgtcatt ggaacctttt caaatgcttg tctcacctta 4067521 tttgtattcg gcacctgagt cagcggattt ccgcacgtca caataatcat ctcaatcgca 4067581 ggatcagcag cggtcaacac ttcttcagcc tgtgtcatca ttgaaaaaga acgggatgtt 4067641 gtttttaatt ccggcagcgt cagctttgtt tttgcaaagc tctcaccaat ctggacattt 4067701 ccgaaattcg cgccgccgcc cttaattccg acatttccgc ttgccgccac aagtgcatca 4067761 atccaacgaa tcgttccccc gccgttttta tatcgctgca tgccaagccc cataaaagta 4067821 gacaccggac catcagcata caaacctgcc aaatactcca gctcctccat agaagtttct 4067881 gttttcacaa taaactcttc cagagaaacg gtcttcaaaa gctctttcac atcatcaaaa 4067941 ccgacagaat gctcagaaat aaacgtttca tccgttcttc ccatctcaat cagaaccttc 4068001 aaaacggctg ccgcaagcca gccgtccatt ccaggcttta cagagatata gcggtcggca 4068061 agcttagcag tcgggttgaa gatcggatca atcaccgtaa tcgtggcgcc cttctttttc 4068121 acctgctgca agtgatggta taagtgcata tttgttcttg atacatttct tccccacaca 4068181 acaacatgct tgctgttgta aatatcaagc ggtccgtgac cgtacgaacg gccaaaatcc 4068241 cagctttgcg cctcgatacc ggagccccag catatgcttc cgacgatttc ggtcacgccg 4068301 ccatatccat taaaaaaacg ctgatcaagc gcttttaaca gaccgttatt cgcataatca 4068361 tggctgtgca aaacagcagt cgtctccgac gtttccttga tttcccgaag tttatcggca 4068421 atttcatcaa gtgcctgctc ccaagaaatc cgcacaaact cgccattttg ttttttcatt 4068481 ggatagcgaa gccgatcagg cgaatttgtt tttgtctcaa gcattctgcc gcggccgcag 4068541 attttacctt ccgtaatcgg atggtttgga tctccgtcca cttttgttac ctttccatca 4068601 tcaacagtca ccaaaaagcc gcagctgtcc caacaattca gcggacatgc cgactgatgc 4068661 actttgctca tcgccgtctt ctccttacct tctatatgaa aaagcatgag tgtcggccta 4068721 tttatgaagt aggctcctca tgcttgacta gtactttttt tagttttctt tcaaattctc 4068781 ttctcggaat cataacactg tgagagcatc cctcacactt aattcgaata tccattccca 4068841 tgcgtataat tttccagctg ttcgctccgc atggatgcgg ttttttcatt tctacgatat 4068901 cattcaggcc aaagtcttta tccgccaaga cccttcacct cttttcctaa actgctgtat 4068961 ctattgtaca aaaaaactga tcataagagc aatcaagata cccgaaaaga aatacatcct 4069021 cttatttcca tttactcaaa ataggatata agagcagaca aactaacaaa tacaaattga 4069081 gcatcccata tatcggatac aagaacgcga tcaaatcaga aaatccgaaa gaagtaaaag 4069141 gtaccattaa cactaacaaa atcaacacaa tcatccatct cggcatatga ataaacgcca 4069201 tcagccggct ggacaaaccc agcaaaccag ctaccgtcgt cgtgtaaatc gccaggcaca 4069261 gcaccgccgt catacataaa aaaaggaaat aaggcgcacc ctccagaacg gcaaacagcg 4069321 gtatttcaaa ctgagaaagg gagcccgcca gctccaccaa cgtttcatta taaacaaatg 4069381 agatcacgcc aaaaataaga ccgcttgcca cacttgcgat ttttgcttct ccgagccctt 4069441 tcatctcttt cccaacagag gataaaatcg caacaactga aaggatgttt aaagaggtaa 4069501 acgtaatgct cgcaggccag ttatactgct gggacaaatc aatcgtccac gtatggtgat 4069561 gtgtgctctg aaaggagatc agcgcatata aaagccccgc tactaacaca ggaatcaaaa 4069621 tactatttat agataatatt cctttcacat cccacaaaaa caagcacact gtcacgatgc 4069681 aaatcagcgt gattccccac cagaaaggaa gcttgtacat ttgcagggtc acaccgcctc 4069741 cggcaatcat caccatagtc gtcgaaaaca aataaaaaat gatgaggaca tcataaattt 4069801 tcgccagcca tggccccatt aaatgctcca gaaccggcag aaaatgagtg gattgaacct 4069861 taaaactgat tttcatcaca atataagacg agaaaatgaa cataattgta aacagcacaa 4069921 tagcaagtcc gctttccgcc ccaaaaaact gccatatctc ctgaccgctc gcatatccgg 4069981 ccccgatcag gctccctaat atgagcagca tccacttcat tccggctctc cacaacacta 4070041 tcacctcata gacaaagttc agcttgttcc cgttattgtt actatataaa taaaggaaag 4070101 caaacatgcc atattttcat agacatttga acacaagctg aaattatcat acgaaataca 4070161 cataaaaaag actgctaata cggcagtcta aaaagagata tttatttgtt tgtccgcgga 4070221 atgaagaagt gaacttcact cttcactttt ttctaaccat tcctacctat tcaagtgttt 4070281 cataagcaga ccattgcttg atcatgatcg aggcaatggg ggacaatact tgtaatcgcc 4070341 cactaaccat tcatatcatg ccctctactt ttttaaaatc tctggtgcca tacacaaagc 4070401 ataaaaaatc atactgctgg atatactgta aacaacctta cataactaca cacaccatag 4070461 caattctgtt acctactata acaaggaagt gaaacccatg aatcgaaaag gcgggctttt 4070521 ttcttctcag gaacgagtaa agcaatatgt ttcacataca gatgctgcag cggcaaaaca 4070581 aatccaaacc atcctttctt catccttacg taaagctgct ggcaaaccaa ttgtcgtggt 4070641 ttgtatcgga acagaccgtt caaccggtga ctcattaggc ccgctcgtag gaatgaaact 4070701 caaacagatg cagctcacca gattccatgt ctacggaacc ttatctgacc ccgtccatgc 4070761 tgtgaacatg aaggataaaa tcaatgacat tcataaatta cataaaaacc catttgttat 4070821 agcagtcgat gcatgcttag gccgcgttaa gagtgtgggt tcatttcaaa tcggggacgg 4070881 gccattaaag cccggagccg gtgtacaaaa agaccttcct gaagtgggag atcttcatat 4070941 taacggaatc gtgaatgtga gcggttttat ggaatatttt gtattgcaaa atactagact 4071001 caacttggtc atgaatatgg caaatgttct agcggaaggt ttgagtttaa cagatcggac 4071061 agagtggagg caagaacgcc ttaacccgtt gcaaaggctc actgggcgca tataaaataa 4071121 aaaccatctt cgtttgaaag atggtttttt catttatgat tctcgttcag acaaaagctc 4071181 taaaatccgg tcaaggtctt cattagagaa aaattcaatt tcgattttgc cttttttctt 4071241 ctgtctttta atattaactg ttgttccaaa ataattttgg agataggatt cccgttcttt 4071301 tagaaccgca tctttcacag gttctttttt ctttgtttca cgtggaacat tctgattcaa 4071361 ctgctgaatc agctgctcaa gttggcgaac attgagctgc tccgcaatca ctttttgtac 4071421 cagcggttca agcttatttt tgttttttaa gccaagaagc gtgcgtccat gtcccataga 4071481 aagcgtgcct tcggcaataa gctgttgaat attttctggc agtgtcagca gtcttaaatg 4071541 attcgcaata tgcggtctgc ttttcccaag acgtttggca agctgctctt gtgtgagatc 4071601 taagtgtttc aaaagggagt catatgcctg agcctcttca agcggagata aatcttcacg 4071661 ctgaaggttt tctaataaag caatttccct cattaacgcc tctgataatt cacggacaat 4071721 ggccggaact gtatctaaac ctgccagctt tgccgctcga aaacgccgtt cacccgcaac 4071781 aatatcatag ccttttaaag attttctgac gataagcggc tgaagaatgc catgctgcag 4071841 cacagattct tttagttcag ctaatgcctc gtcatcaaag tgttttcttg gctgataagg 4071901 attagggcgt aaatcggcaa ttttaatttc ttcaactgtc tcttcagaca aatctacctg 4071961 attaaataac gcattaatcc cttttccaag gcctttagcc attcgcagcc acttcctttg 4072021 ctaaatctaa atatacttcc gcacctcttg accgcggatc gtataaaatg atgggttttc 4072081 cgtgactcgg tgcctcactc agacggacat tacgcggaat aactgtctta tatactttat 4072141 ccctaaaata ctttttaacc tcttcaatca cttgaatgcc aaggtttgtc cgggcatcaa 4072201 gcattgtcag caatacacct tcaatcatta aatcagtatt caaatgcttt tgcacaagac 4072261 gtactgtatt taataactgg ctgagaccct ccaaggcata atattcgcac tgtacaggaa 4072321 tcacaacgga atccgaggca gtaagggcat taatcgtcag caagcccaat gacggcggac 4072381 aatcaatgat aatataatca taattttgct ttactgcttc aagcgctctc ttcaatctca 4072441 cttctcttga tattgtagga accagctcga tctcagcccc tgcaagctga atcgtcgcag 4072501 gaatcacatc caagttctct actgtcgttg ctttaataat atctattaca tctgcatcat 4072561 ctactaaaat atcgtacaca cactgctcta catcggcttt ttcaatccct aatccgcttg 4072621 tcgcatttcc ctgcggatca atatctacca gcagaaccct tttccctatg taagccaaac 4072681 atgccccaag gttgacagac gtcgttgttt tgccgacccc gcctttttgg ttcgtaattg 4072741 ctatgatttt tcccacgatg tcacctactt tcacatgaac atgtactatc ttgcttctat 4072801 tctatcaaaa aaagattaaa gcgtttcatt tttttcatca ttttgttccg aatcagaagg 4072861 gaaataattg aaaattcaag cacgctttat gctttctctt ataaattctg caatttctat 4072921 gtttttttga cttaaaaaag gaatttctta aagaaaaaaa gaagaagtca cagtacagaa 4072981 cgtggaaaca ggatggtgag aaaatggttt atcaaacgaa gagagatgta cccgttacgc 4073041 tgatgattgt gtttctcata ttactgatac aagcagatgc cattgttcct tttgtgctgg 4073101 gaaatatgag agtttccggc tggatcattt ttattctgct gactctttta aatggactca 4073161 tcatttggag ctttattgac ctaaaatatg tattgaagga acaccatctg atcattaaag 4073221 ccggattgat caaacatcaa attccttatg aaaacatcga taaagtcgtt caaaaaaaga 4073281 aactatggtc cggttttcgt ctgatcggct ctcgccatgc catcacaata tattatcagg 4073341 ggggatgggg acatgcagta atttcaccgc aaaaatctga agaatttatc cacaagctca 4073401 aagaaaagaa ttctaatata ataatattca ctaaaagtaa gtgattacct tttgttaaaa 4073461 atataaaaag ctctcctgct tttcaggaga gcttctattt tggtatgcga atcgttaatt 4073521 gaatatattc ttcaaattct tcttcttccg tattcaattt tacaccgctg tcttccacca 4073581 ttgatagtga ctggcgaatc gtgttcatcg caattcttgt atctctgctg aatgctttgc 4073641 gtctcggctt tggctttctc tggccttgct ccagcatttt caccacgcgg tcttctgtct 4073701 gctttacatt taaacttttc tcaataatct ctgtgagcag tgtgacttgg agctcaggct 4073761 gtttcagcgg aatcagtgct ctggcatggc gctcggtgat tttcttctcc ataatcgcct 4073821 cttggaccgg ctgaggcagc tttaataacc gaagcttatt cgcgattgta gactgccctt 4073881 ttcctaagcg ctgtgcgagt gcctcctgtg ttaaatcatg cagctcaagc agcctagcat 4073941 aagcatgcgc ttcctcaata gaagacagtt cttcccgctg caagttttcg attaacgcca 4074001 cagaagcggt ttccgtgtcg gaaaaatcct taataattgc cggaatcttt tcccactcaa 4074061 gcgattgcac cgctctccag cgtctttcac ctgcaatgag ttcgtattgg ccttcttctt 4074121 ctgtatgcct aacaacaatc ggctgaataa tgccgtgtgt atgaatggtc attgctaact 4074181 ctttgatttt ttcatctgag aaaatggtgc gtggctgaaa acggttggga acgatagcat 4074241 ttaccggtat ttccagaatc tcttctttgt ttgtatcatg ttcagcaatc tccggctcct 4074301 gttccttctc accaagcccg aagaaacgag agaatgaatg cttcatgtac ctacaccacc 4074361 tttaaaaact gccattttta taattctatt ttctcatggt ttttcctgct gtacatccat 4074421 caattttgat gaaaatatga tggtattgtc atatcaggct gtctaaatta cccttcaatt 4074481 ggcgatttat taggagttcc cggttttctt ggatacttct taggtgtatt ttttattttg 4074541 cgtatcacca taatattacg atcgctttct tcaataggca gcttaaaaga atggatattc 4074601 tcaagttctc ctccaagcgt cgtgattgct tttttgcctg cattcagttc ttcttcagct 4074661 gatgcggctt ttaaagcaac aaataaaccg tttttcttca ccagaggcaa gcaaagctca 4074721 ctcaaaacag ataatctcgc aactgcgcgc gccgtcacaa tatcatagct ttcacgcacg 4074781 tctttccgtt gcccgaacgt ttcagctctg tcatggcaga atgttgtatt ctccaattgc 4074841 aaagcttcag acaacttttc taaaaacgta atccgtttgt ttagtgaatc cacgattgtg 4074901 acatggaggt gcggaaagca tatttttatc ggcagacttg gaaaacccgc tcccgctcca 4074961 acatcacaaa tcgtgttcac ctgattgaag tcgacataaa aagcagctgt aatggaatca 4075021 taaaaatgct ttaaatacac ttcttttttc tctgttattg aagtcagatt gattttttcg 4075081 ttccattcaa ccagcatgtc gtaatacagc tcaaattgct ccagctgacg gggagaaagg 4075141 gagatccctt tttccgccaa accagaagtg aattcttcaa tattcatgcc gtcatccttt 4075201 ctactcggct atcttcgcaa tgcgtccctg ctctaaatac accaatagaa ttgaaatgtc 4075261 cgccgggttt acaccggaaa tgcgggaagc ctgggcaaca gacaaaggcc gtacattttt 4075321 cagtttttga cgcgcctcgg tcgcaatccc cttaattgcg tcataatcaa ttcggtctgg 4075381 aattttttta ttttccatct tcttcagttt ttccacttgc tgaagagatt tttcaatata 4075441 tccttcatat ttcacttgga tttctacttg ttctgccacg tcttgaggaa ccggcacttc 4075501 tggcggcgcc agttttgtga ctgtttcata gttcatttca ggacgtttca tcaagtctgt 4075561 gccgcgaact ccatctttca attcgcttcc gccaagagaa cggatatatt cttgattttc 4075621 cggagacggc ttgataatta cagaatgaag acgttttttc tccgcctcga tcgccgcttt 4075681 tttcttctca aaagccgcat agcgctcatc agaaatcaat ccaatgcgat gtccgatttc 4075741 tgtcagacgc aaatcagcat tgtcatggcg aagcagcaat ctgtattccg cacgtgatgt 4075801 caaaagacga tatggctcat tggtaccttt tgtcacaagg tcatcaatca gaacaccaat 4075861 ataggcgtca gaacggctta gaattacttc ttcttttcca agcgcttttc gtcctgcatt 4075921 gattcccgcc ataatccctt gtcccgcagc ttcttcataa ccggatgttc cgttaatttg 4075981 gcctgcagta taaaggtttg tgattttttt ggtttcaagt gtcggccata gctgtgtcgg 4076041 tacgattgca tcatactcga tcgcatagcc ggctctcatc atttgcacgt tttcaagtcc 4076101 aggaatcgtt gcaagcattc tttgctgtac gtcttctgga agacttgtag ataaaccttg 4076161 gacatagact tcctgtgtat ttctgccttc cggctcaagg aagatttggt gacgcggttt 4076221 atcattaaaa cggacaactt tgtcttcaat ggatgggcag tatcttgggc ccgtaccttt 4076281 gatcataccg gaatacatcg gtgaacggtg caggttgctg tcaataatct catgtgtctc 4076341 agggcttgta tatgtcagcc agcaagggag ctgatctgtg atatattcca ctgtttcata 4076401 tgagaaagcg cgaggcacat cgtcaccagg ctgaatttcc gttttgctgt aatcaatcgt 4076461 gtcgctttta acgcgaggcg gcgtacctgt tttaaaacga acaaggtcaa aaccgagttc 4076521 ctccaaatgc tcagaaagct taatagaagg ctgctggtta ttcgggccgc ttgagtaaga 4076581 cagatcgcca agaatgatac gtcctcttaa atatgtccct gtcgtcatga caactgcttt 4076641 cgcacgataa tgtgcgcctg tttgtgtaat aacgcctcgg cattcgccgt cttcaacgat 4076701 cagccgctcc acaattcctt gcagcaatgt taagtttggt tctttttcaa gcgtattttt 4076761 catttcgtgc tgatattgga atttgtctgc ttgcgcacgc aatgcacgaa ccgcaggacc 4076821 ttttcctgta ttcagcattc tcatttgaat atgtgtttta tcgatgtttc ttcccatttc 4076881 tccgccgagc gcgtcaattt cgcggacgac aatccctttt gcggggccgc cgacagacgg 4076941 attacatggc ataaatgcaa ccatatctag gttgatggtc aagacaagcg ttttggcgcc 4077001 ttggcgtgca gatgcgaggg cagcctcaac accggcatgc ccggcgccaa tcacaatcac 4077061 atcgtattgg cctgcttcat accccatgat tctagttcct cctttaatta ttttcctaaa 4077121 cagaattgag aaaagagctg atcaattaag ctttcgtgga cagaatctcc aatgatttcc 4077181 cctaaaagct cccagcatct tgtaaggtca atttgcacca tgtcgatcgg gacatcctgt 4077241 tcgatgccgc taagcgcatc ttcaatggcg cgttttgctt gctgtaaaat agtgatgtga 4077301 cgtgtgttgc tgacataagt cagatcaccg ctttcaatgg cacccgtgta gaacagtgat 4077361 tgaatcgctt cttccagatc attgatgcct tcctctttta aaagagatgt cgtaacaact 4077421 ggacgtccat tggcaagctc acggacacgt tcagtgtcaa tcttcggctc aaggtcagtc 4077481 ttattcaaaa tcacgataac atccatgccc tcaacggctt caaaaagctt cacgtcttct 4077541 tcagaaagct cttcactata attaagcaca agtaaaatca ggtccgcttc ctttaggacc 4077601 tggcgagaac gttcaacacc gattcgctca acaatatcct ctgtttcacg aatacctgct 4077661 gtatcaacca gacgaagcgg aacgcccctt acattcacgt attcctcaat cacatcccgt 4077721 gtcgttccgg gaatatcggt tacaatggct tttgcctcat gaacgaggct gttcagaaga 4077781 gatgattttc ctacgtttgg ccggccgata atgacggtag aaagaccttc acgcaagatt 4077841 tttccttgct cagaagtcct cagcagcgtc tcaatttcct ttttcacggc ggttgccttt 4077901 tcgactaaaa tctgatgcgt catttcctct acatcatcat actccggata atcaatattc 4077961 acctcaacat gggccagtgt ttctaaaatc tcactgcgca aacggcgcac caaagcagaa 4078021 agacgccctt ccatttgatt catagcaacg ttcattgccc ggtccgtttt cgctctgatt 4078081 aagtccataa ccgcttccgc ctgtgaaaga tcgattcggc cgtttaaaaa cgcacgtttc 4078141 gtaaattcac caggctctgc cagtctcgct ccctctctca atgcaagctg aagcacttgg 4078201 ttcacagtca caattccccc gtgacagtta atctcgatga catcttctcg tgtaaaagtt 4078261 ctcggcgctt ttaacactga taccattact tcctcaacga cacgatccga aggtctgtct 4078321 acgatatgac cataatgaat cgtatgtgat tcgaccgagc tgagtgtttt ccccttcggt 4078381 cccttataaa ttttatctgc gatttgaatg gcttctggtc cgctcaaccg tacaatcgca 4078441 atcgcgcctt ctcccatcgg tgtggaaatt gccgcaattg tatccatgtt gttcacctct 4078501 ctttacttat acttcatcta tataaaaaaa tttttattat gccaaaacta aaagataaca 4078561 tagtttggtt cgaagtggaa gatttgttat ccacagaaat agaaattcgt cccttattac 4078621 tttaacttat ccacatgtga ataacaatta attttatttc ctgaacttcc tttttatcaa 4078681 caggatacac ctaaaaagaa aaaacttaaa cggcaaaacc ttgatattac taggaaaagt 4078741 agatttttcg gatacaaaaa aaccgaaatc caatttttat cggacttcgg ttttatgcta 4078801 tcttttatgg gaaataacga gatgacgatt ttcgccttca cccattgaat atgttttgat 4078861 ctggtggttt gcatatccag aaagagtatc gtgaataatt tttctttcgc tggacggcat 4078921 gggctcaagc tggatggatt ttttcgtttt caaaacctgg tcagcaagct tgatggccag 4078981 ctggctcagt gtttcttttc ttttcaaacg atagttttct gcatccaccg tcacattttt 4079041 atattggcct ggataacggt taagggcaag ctgtgtcaaa gtttcaaggg cgtttaaagt 4079101 ttgtcctctt ttcccaatca acaatgctgc cttttcacct gttatatgat atctcactgt 4079161 ctttttgctt tcttgaacag tcacatcaga cttcccggca atggcttcgg caatcgtttg 4079221 aagatataac ttcgcttgct gaatcggatc aatcttttca accagcttta cgatcgcagg 4079281 ctttttaccg aaaataccga gaaacccttt gtttccctct tcaataacag taatttctac 4079341 cttatccttc gttaatccca actcttgcaa tccggactgt actgcttcat cgacatttcg 4079401 ccctgcagca gtcacattcc tcactttttc tttcctccgg ctttttgcgg ctcaggattt 4079461 tttttaatat caggtccttt aatgaggaaa gtttgcgcaa tcataaacaa gttaccaact 4079521 acccaataaa gagaaagagc cgccgggaag ttgatcgcaa atacgataat cataattggc 4079581 ataatccaaa gcatcatcgc catttgcgga ttttgctgcg cattgccagc catcatcagt 4079641 ttttgctgaa caaatgtagc gacaccggca acgataggaa gaatatagta aggatctttt 4079701 tctcctaagt caaaccataa gaagctatgc tctgaaatcg cctgggttct catgatcgca 4079761 tgatagaatc caattaaaat cggcatctgg atcaaaatcg ggaaacatcc cgccaatgga 4079821 ttgacaccat gcttttggaa taaagccatt gtttcctgtt gaagcttttg ctgcgttttt 4079881 tgatcctttg agctgtattt ttctttaagc ttttgcattt ccggctgtaa agcctgcatc 4079941 gctttcgaac ttctcagctg cttaatcatc agcggtaaaa ttaataaacg aattaaaatg 4080001 gtaactagaa taattgaaag cccgtagtta tctcccgtca atttcgctac atacgtaatg 4080061 agctcagaca atggatatac tacgtacttg tcccagaaat gcggactatc tgcagtgatc 4080121 ggctctttca cactcgagca tccagccaaa agcatgaata cgccaaccat acttaatagc 4080181 aaccctattc tccttttcaa caacatttcc tcctataatt aatctttaca ctcttttatt 4080241 gcaaagcata cttgtatgta ttttagcatc tttcagtttt aaatggtgtc tttttctgat 4080301 caaccagaaa ggaagcgctt ttaaaagttg taagaaagca gtggtgatgc ctactttgac 4080361 gaagatttct tatataatga agactttctg aatagatgct gcagactttt tttcgtttcc 4080421 tcatatgtca gctggctcgc cggttttctg gcaataatga tgtaatcctt ttccttcagt 4080481 ctctctttct cttcaagaaa ggcctgccga atcaaacgtt tgatccgatt tcgcatcaca 4080541 gcattgccaa tttttttgct gacggaaagc ccgacacgca gttcatcatt ttcaggctga 4080601 tcaagcgtat ataagacaaa ctggcggttt gcaactgatg tcccatgttt aaacactttt 4080661 tgaaaatctt catttttctt taaacgattt cgcttcttca aatgactcac tccgatactg 4080721 gctggcagaa acttttaaaa tttattatga acatgagatg catctgaacc aggaagcatg 4080781 ccccggttca ttacgcatca catctatctt ttcccataac gtgaaaaaag accactgaca 4080841 ttattcagtg gcctaagctg ataatacttt tctgcctttg cggcgacggc gtgctaaaac 4080901 tagacgaccg ttttttgaac tcatacggct tctgaagcca tgaactttgc tgcgtttacg 4080961 gttattcggt tggaatgttc ttttcattta tgacacctcc ctcgaggaat agctgttaaa 4081021 gacagtctta cttattatat ttgcgttacc tattcattgt caacttcact agtgctttta 4081081 tttcttgcaa ccataatagg ataccatacc ttttcaactt tcgaaacctt attttttaga 4081141 ttccttaatt ttacggaaaa aagacaaatt caaacaattt gcccctaaaa tcacgcatgt 4081201 ggat //